Guide to the Human Genome
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Search of human proteins with 169168202

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
         (460 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]           931   0.0  
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]           929   0.0  
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]           929   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    66   6e-11
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    66   6e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      65   1e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      64   3e-10
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             59   1e-08
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    58   2e-08
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    58   2e-08
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    58   2e-08
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     57   3e-08
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       57   5e-08
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       55   1e-07
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          55   1e-07
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                55   1e-07
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    54   4e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    53   5e-07
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    53   5e-07
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    53   5e-07
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          52   1e-06
gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                52   1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        52   1e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   1e-06
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   1e-06
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     52   1e-06
gi|40807477 retinoic acid induced 1 [Homo sapiens]                     52   1e-06

>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  931 bits (2405), Expect = 0.0
 Identities = 460/460 (100%), Positives = 460/460 (100%)

Query: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60
           MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR
Sbjct: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60

Query: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120
           ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE
Sbjct: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120

Query: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180
           RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN
Sbjct: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180

Query: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240
           PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG
Sbjct: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240

Query: 241 GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300
           GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP
Sbjct: 241 GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300

Query: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360
           CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD
Sbjct: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360

Query: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420
           AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL
Sbjct: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420

Query: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460
           LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL
Sbjct: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460


>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  929 bits (2400), Expect = 0.0
 Identities = 459/460 (99%), Positives = 460/460 (100%)

Query: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60
           MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR
Sbjct: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60

Query: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120
           ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE
Sbjct: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120

Query: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180
           RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN
Sbjct: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180

Query: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240
           PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG
Sbjct: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240

Query: 241 GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300
           GKGQRAAGAERVL+NGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP
Sbjct: 241 GKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300

Query: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360
           CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD
Sbjct: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360

Query: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420
           AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL
Sbjct: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420

Query: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460
           LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL
Sbjct: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460


>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score =  929 bits (2400), Expect = 0.0
 Identities = 459/460 (99%), Positives = 460/460 (100%)

Query: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60
           MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR
Sbjct: 1   MTLRAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGR 60

Query: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120
           ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE
Sbjct: 61  ARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGE 120

Query: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180
           RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN
Sbjct: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180

Query: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240
           PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG
Sbjct: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240

Query: 241 GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300
           GKGQRAAGAERVL+NGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP
Sbjct: 241 GKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARP 300

Query: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360
           CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD
Sbjct: 301 CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSD 360

Query: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420
           AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL
Sbjct: 361 AARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGREL 420

Query: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460
           LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL
Sbjct: 421 LGSEPRNGTLESICSLHVGNGARAHVLELHPRSLSQYSHL 460


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 97/350 (27%), Positives = 119/350 (34%), Gaps = 29/350 (8%)

Query: 48  VTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAG 107
           + GA   +  PG A A    G  G    + A   LG +  T  P   G +    P    G
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474

Query: 108 PLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGR 166
           P       G AGE G  GA G+   V    PPG         F    G  + P+ +PG R
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDG-LAGPKGAPGER 533

Query: 167 RGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFG--AP 222
               L   +G   +PG    P L   RG  + R  D   +       AP      G   P
Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARG-LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 592

Query: 223 RGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGL---AGGVEPPGWSRER 279
           +G+R  +P    FP   G  G+     E+ L    G R  LPG     G   PPG     
Sbjct: 593 QGARG-QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG-LPGKDGETGAAGPPG----P 646

Query: 280 AGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFV 339
           AG    R     P       P   QG P       P PP        +  PG A  PG V
Sbjct: 647 AGPAGERGEQGAP------GPSGFQGLPG-----PPGPPGEGGKPGDQGVPGEAGAPGLV 695

Query: 340 TLAFRSRLPLLR-SPGPEGTSDAARAP-APGLRDRDLRAAPPRPRPSQRP 387
                   P  R SPG +G       P  PG       + P  P  +Q P
Sbjct: 696 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 745



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 100/383 (26%), Positives = 126/383 (32%), Gaps = 62/383 (16%)

Query: 45  SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRR-GGLRSRTDPA 103
           +P + G       PG   A  + G  G + E  +    G+    +GPR   G R RT PA
Sbjct: 280 TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP-MGPRGLPGERGRTGPA 338

Query: 104 FGAG------------PLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFV 150
             AG            P   V   G  G  G+PGA G+  P  A  P G           
Sbjct: 339 GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG-------- 390

Query: 151 FPPGKTSAP-RPSPGGRRGRP----LGAARGTGLNPGLS-----PRLQEPRGHQSAR--- 197
            P G+   P  P P G  G P    +  A+G+   PG++     P  + P G Q A    
Sbjct: 391 -PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449

Query: 198 ----RTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEAS--GGKGQRAAGAER 251
               +T     AG+   + P        P+G+     + GK       GG G      ER
Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509

Query: 252 VLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGL-----SRDSPQVPRSGSWARPCREQGH 306
                RG     PG  G   P G   ER  +GL     +   P  P            G 
Sbjct: 510 GAPGNRG----FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 565

Query: 307 PAVLALQSPAPPSLARAAARRRGP----GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAA 362
           P     Q    PS A     R GP    G   +PG   + F         PG  G     
Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG--VMGFPGPKGANGEPGKAGEKGLP 623

Query: 363 RAPA----PGLRDRDLRAAPPRP 381
            AP     PG       A PP P
Sbjct: 624 GAPGLRGLPGKDGETGAAGPPGP 646



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 106/369 (28%), Positives = 122/369 (33%), Gaps = 69/369 (18%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSAT--LGPRRGGLRSRTDPAFGAG 107
            GA  +    G    A Q+GD GA   +  + + G Q  T   GP+  G R    P    G
Sbjct: 840  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK--GARGAQGPPGATG 897

Query: 108  PLPLVSRLGHAGERGSPG-------AGDVNPVSA---SSPPGRPDPLLLTTFVFPPGKTS 157
                  R+G  G  G+PG       +G   P  A   S PPGR     L     PPG+  
Sbjct: 898  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957

Query: 158  AP-RPSPGGRRGRP----LGAARGTGLNPGLS-----PRLQEPRGHQSARRTDTASRAGW 207
             P    P G  G P    L   RG    PG       P L  P G    +    AS    
Sbjct: 958  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGAS---- 1013

Query: 208  ATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLA 267
              R  P        P G   L   AG+ P   G  G              GP    PG  
Sbjct: 1014 GDRGPP-------GPVGPPGLTGPAGE-PGREGSPG------------ADGP----PGRD 1049

Query: 268  GGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARR 327
            G     G  R   GA  +  +P  P S   A P  +QG       Q P  PS    A   
Sbjct: 1050 GAAGVKG-DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108

Query: 328  RGP-------GGATEPGFVTL-AFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPP 379
            +GP       G A EPG   L   R    L   PGP G S    A  P        A P 
Sbjct: 1109 QGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP--------AGPS 1160

Query: 380  RPRPSQRPV 388
             PR    PV
Sbjct: 1161 GPRGPPGPV 1169



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 97/368 (26%), Positives = 117/368 (31%), Gaps = 87/368 (23%)

Query: 71  GARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG----A 126
           G   E+A    LG     +GP   G R    PA   GP          G +G+PG     
Sbjct: 185 GGFDEKAGGAQLGVMQGPMGPM--GPRGPPGPAGAPGP---------QGFQGNPGEPGEP 233

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKT----SAPRPSPGGRRGRP-LGAARGTGLNP 181
           G   P+    PPG            PPGK      A +P   G RG P    ARG    P
Sbjct: 234 GVSGPMGPRGPPG------------PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP 281

Query: 182 GLSPRLQEPRGH-----------------QSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
           GL P ++  RG+                 +S    +  S      R  P  R   G P G
Sbjct: 282 GL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG-PAG 339

Query: 225 SRRLRPDAGK-----------------FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLA 267
           +   R + G+                 FP A G KG+      R     +GPR   PG  
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE-PGTP 398

Query: 268 GGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARR 327
           G   P G S      G+          G    P    G P       P  P   + A   
Sbjct: 399 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP----GFP------GPRGPPGPQGATGP 448

Query: 328 RGPGGAT-EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAP----PRPR 382
            GP G T EPG     F+        PGP G    A  PA     R  R  P    P   
Sbjct: 449 LGPKGQTGEPGIA--GFKGEQGPKGEPGPAG-PQGAPGPAGEEGKRGARGEPGGVGPIGP 505

Query: 383 PSQRPVSG 390
           P +R   G
Sbjct: 506 PGERGAPG 513



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 97/382 (25%), Positives = 120/382 (31%), Gaps = 69/382 (18%)

Query: 24   PGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARR--------- 74
            PG+  +     + G A A    P + G       PG   +   QG  G R          
Sbjct: 674  PGEGGKPGDQGVPGEAGA----PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729

Query: 75   ERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA-GDVNPVS 133
             + A+   G   A   P   G+      A  AGP      +G  G  G+PG  G      
Sbjct: 730  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 789

Query: 134  ASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEP--R 191
               PPG          V PPG   +      G RG P    RG    PG +     P   
Sbjct: 790  PIGPPGPAGANGEKGEVGPPGPAGS-----AGARGAP--GERGETGPPGPAGFAGPPGAD 842

Query: 192  GHQSAR-RTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAE 250
            G   A+     A + G A    P        P+G   +          +G KG R A   
Sbjct: 843  GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV----------TGPKGARGA--- 889

Query: 251  RVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG----LSRDSPQVPRSGSWARPCREQGH 306
                 G    +  PG AG V PPG +      G      +D P+  R  S   P    G 
Sbjct: 890  ----QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS--GPPGRAGE 943

Query: 307  PAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEG-TSDAARAP 365
            P    LQ PA P   +      GP GA  P                PGP+G         
Sbjct: 944  P---GLQGPAGPPGEKGEPGDDGPSGAEGP----------------PGPQGLAGQRGIVG 984

Query: 366  APGLRDRDLRAAPPRPRPSQRP 387
             PG R    R  P  P PS  P
Sbjct: 985  LPGQRGE--RGFPGLPGPSGEP 1004



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 90/360 (25%), Positives = 112/360 (31%), Gaps = 41/360 (11%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G       PG   AA   G  G + +R      G + A   P + G R  T P   
Sbjct: 740  PGAQGPPGLQGMPGERGAA---GIAGPKGDRGDVGEKGPEGA---PGKDGGRGLTGPIGP 793

Query: 106  AGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPG 164
             GP       G  G  G   AG      A    G   P     F  PPG    P      
Sbjct: 794  PGPAGANGEKGEVGPPGP--AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 851

Query: 165  GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
            G  G+   A       P  +P  Q P G    +    A     AT   P      G P  
Sbjct: 852  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT-GFPGAAGRVGPPGS 910

Query: 225  SRRLRPDAGKFPEASGG-KGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
            +    P     P    G KG R        ++G   R+  PGL G   PPG   E    G
Sbjct: 911  NGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 963

Query: 284  LS-RDSPQVPRSGSWARPC-------REQGHPAVLALQSPAPPSLARAAARRRGPGGATE 335
             S  + P  P+  +  R          E+G P +           A  A+  RGP G   
Sbjct: 964  PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023

Query: 336  PGFVTLAFRSRLPLLRSPGPEGTSDAARAP----APGLR----DRDLRAAPPRPRPSQRP 387
            P  +T            PG EG+  A   P    A G++    +     AP  P P   P
Sbjct: 1024 PPGLT-------GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1076



 Score = 33.1 bits (74), Expect = 0.54
 Identities = 49/154 (31%), Positives = 55/154 (35%), Gaps = 28/154 (18%)

Query: 49   TGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGP--RRG-----GLRSRTD 101
            TGA      PG   +    G  G + +R  A + G    + GP   RG     G R    
Sbjct: 1061 TGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS-GPAGARGIQGPQGPRGDKG 1119

Query: 102  PAFGAGPLPLVSRLGHAGERGSPG-------AGDVNPVSASSPPGRPDPLLLTTFVFPPG 154
             A   G   L    G  G +G PG        G   P   S P G P P      V P G
Sbjct: 1120 EAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP------VGPSG 1173

Query: 155  KTSA---PRP-SPGGRRGR--PLGAARGTGLNPG 182
            K  A   P P  P G RGR    G A   G NPG
Sbjct: 1174 KDGANGIPGPIGPPGPRGRSGETGPAGPPG-NPG 1206


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 66.2 bits (160), Expect = 6e-11
 Identities = 97/350 (27%), Positives = 119/350 (34%), Gaps = 29/350 (8%)

Query: 48  VTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAG 107
           + GA   +  PG A A    G  G    + A   LG +  T  P   G +    P    G
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 405

Query: 108 PLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGR 166
           P       G AGE G  GA G+   V    PPG         F    G  + P+ +PG R
Sbjct: 406 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDG-LAGPKGAPGER 464

Query: 167 RGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFG--AP 222
               L   +G   +PG    P L   RG  + R  D   +       AP      G   P
Sbjct: 465 GPSGLAGPKGANGDPGRPGEPGLPGARG-LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP 523

Query: 223 RGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGL---AGGVEPPGWSRER 279
           +G+R  +P    FP   G  G+     E+ L    G R  LPG     G   PPG     
Sbjct: 524 QGARG-QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG-LPGKDGETGAAGPPG----P 577

Query: 280 AGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFV 339
           AG    R     P       P   QG P       P PP        +  PG A  PG V
Sbjct: 578 AGPAGERGEQGAP------GPSGFQGLPG-----PPGPPGEGGKPGDQGVPGEAGAPGLV 626

Query: 340 TLAFRSRLPLLR-SPGPEGTSDAARAP-APGLRDRDLRAAPPRPRPSQRP 387
                   P  R SPG +G       P  PG       + P  P  +Q P
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 100/383 (26%), Positives = 126/383 (32%), Gaps = 62/383 (16%)

Query: 45  SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRR-GGLRSRTDPA 103
           +P + G       PG   A  + G  G + E  +    G+    +GPR   G R RT PA
Sbjct: 211 TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP-MGPRGLPGERGRTGPA 269

Query: 104 FGAG------------PLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFV 150
             AG            P   V   G  G  G+PGA G+  P  A  P G           
Sbjct: 270 GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG-------- 321

Query: 151 FPPGKTSAP-RPSPGGRRGRP----LGAARGTGLNPGLS-----PRLQEPRGHQSAR--- 197
            P G+   P  P P G  G P    +  A+G+   PG++     P  + P G Q A    
Sbjct: 322 -PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 198 ----RTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEAS--GGKGQRAAGAER 251
               +T     AG+   + P        P+G+     + GK       GG G      ER
Sbjct: 381 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 252 VLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGL-----SRDSPQVPRSGSWARPCREQGH 306
                RG     PG  G   P G   ER  +GL     +   P  P            G 
Sbjct: 441 GAPGNRG----FPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 496

Query: 307 PAVLALQSPAPPSLARAAARRRGP----GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAA 362
           P     Q    PS A     R GP    G   +PG   + F         PG  G     
Sbjct: 497 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG--VMGFPGPKGANGEPGKAGEKGLP 554

Query: 363 RAPA----PGLRDRDLRAAPPRP 381
            AP     PG       A PP P
Sbjct: 555 GAPGLRGLPGKDGETGAAGPPGP 577



 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 106/369 (28%), Positives = 122/369 (33%), Gaps = 69/369 (18%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSAT--LGPRRGGLRSRTDPAFGAG 107
            GA  +    G    A Q+GD GA   +  + + G Q  T   GP+  G R    P    G
Sbjct: 771  GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPK--GARGAQGPPGATG 828

Query: 108  PLPLVSRLGHAGERGSPG-------AGDVNPVSA---SSPPGRPDPLLLTTFVFPPGKTS 157
                  R+G  G  G+PG       +G   P  A   S PPGR     L     PPG+  
Sbjct: 829  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888

Query: 158  AP-RPSPGGRRGRP----LGAARGTGLNPGLS-----PRLQEPRGHQSARRTDTASRAGW 207
             P    P G  G P    L   RG    PG       P L  P G    +    AS    
Sbjct: 889  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGAS---- 944

Query: 208  ATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLA 267
              R  P        P G   L   AG+ P   G  G              GP    PG  
Sbjct: 945  GDRGPP-------GPVGPPGLTGPAGE-PGREGSPG------------ADGP----PGRD 980

Query: 268  GGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARR 327
            G     G  R   GA  +  +P  P S   A P  +QG       Q P  PS    A   
Sbjct: 981  GAAGVKG-DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039

Query: 328  RGP-------GGATEPGFVTL-AFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPP 379
            +GP       G A EPG   L   R    L   PGP G S    A  P        A P 
Sbjct: 1040 QGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP--------AGPS 1091

Query: 380  RPRPSQRPV 388
             PR    PV
Sbjct: 1092 GPRGPPGPV 1100



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 97/368 (26%), Positives = 117/368 (31%), Gaps = 87/368 (23%)

Query: 71  GARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG----A 126
           G   E+A    LG     +GP   G R    PA   GP          G +G+PG     
Sbjct: 116 GGFDEKAGGAQLGVMQGPMGPM--GPRGPPGPAGAPGP---------QGFQGNPGEPGEP 164

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKT----SAPRPSPGGRRGRP-LGAARGTGLNP 181
           G   P+    PPG            PPGK      A +P   G RG P    ARG    P
Sbjct: 165 GVSGPMGPRGPPG------------PPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTP 212

Query: 182 GLSPRLQEPRGH-----------------QSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
           GL P ++  RG+                 +S    +  S      R  P  R   G P G
Sbjct: 213 GL-PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG-PAG 270

Query: 225 SRRLRPDAGK-----------------FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLA 267
           +   R + G+                 FP A G KG+      R     +GPR   PG  
Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE-PGTP 329

Query: 268 GGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARR 327
           G   P G S      G+          G    P    G P       P  P   + A   
Sbjct: 330 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP----GFP------GPRGPPGPQGATGP 379

Query: 328 RGPGGAT-EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAP----PRPR 382
            GP G T EPG     F+        PGP G    A  PA     R  R  P    P   
Sbjct: 380 LGPKGQTGEPGIA--GFKGEQGPKGEPGPAG-PQGAPGPAGEEGKRGARGEPGGVGPIGP 436

Query: 383 PSQRPVSG 390
           P +R   G
Sbjct: 437 PGERGAPG 444



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 97/382 (25%), Positives = 120/382 (31%), Gaps = 69/382 (18%)

Query: 24  PGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARR--------- 74
           PG+  +     + G A A    P + G       PG   +   QG  G R          
Sbjct: 605 PGEGGKPGDQGVPGEAGA----PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660

Query: 75  ERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA-GDVNPVS 133
            + A+   G   A   P   G+      A  AGP      +G  G  G+PG  G      
Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 720

Query: 134 ASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEP--R 191
              PPG          V PPG   +      G RG P    RG    PG +     P   
Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGS-----AGARGAP--GERGETGPPGPAGFAGPPGAD 773

Query: 192 GHQSAR-RTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAE 250
           G   A+     A + G A    P        P+G   +          +G KG R A   
Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGV----------TGPKGARGA--- 820

Query: 251 RVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG----LSRDSPQVPRSGSWARPCREQGH 306
                G    +  PG AG V PPG +      G      +D P+  R  S   P    G 
Sbjct: 821 ----QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDS--GPPGRAGE 874

Query: 307 PAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEG-TSDAARAP 365
           P    LQ PA P   +      GP GA  P                PGP+G         
Sbjct: 875 P---GLQGPAGPPGEKGEPGDDGPSGAEGP----------------PGPQGLAGQRGIVG 915

Query: 366 APGLRDRDLRAAPPRPRPSQRP 387
            PG R    R  P  P PS  P
Sbjct: 916 LPGQRGE--RGFPGLPGPSGEP 935



 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 90/360 (25%), Positives = 112/360 (31%), Gaps = 41/360 (11%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G       PG   AA   G  G + +R      G + A   P + G R  T P   
Sbjct: 671  PGAQGPPGLQGMPGERGAA---GIAGPKGDRGDVGEKGPEGA---PGKDGGRGLTGPIGP 724

Query: 106  AGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPG 164
             GP       G  G  G   AG      A    G   P     F  PPG    P      
Sbjct: 725  PGPAGANGEKGEVGPPGP--AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQ 782

Query: 165  GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
            G  G+   A       P  +P  Q P G    +    A     AT   P      G P  
Sbjct: 783  GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT-GFPGAAGRVGPPGS 841

Query: 225  SRRLRPDAGKFPEASGG-KGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
            +    P     P    G KG R        ++G   R+  PGL G   PPG   E    G
Sbjct: 842  NGNPGPPGPPGPSGKDGPKGARG-------DSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 894

Query: 284  LS-RDSPQVPRSGSWARPC-------REQGHPAVLALQSPAPPSLARAAARRRGPGGATE 335
             S  + P  P+  +  R          E+G P +           A  A+  RGP G   
Sbjct: 895  PSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954

Query: 336  PGFVTLAFRSRLPLLRSPGPEGTSDAARAP----APGLR----DRDLRAAPPRPRPSQRP 387
            P  +T            PG EG+  A   P    A G++    +     AP  P P   P
Sbjct: 955  PPGLT-------GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSP 1007



 Score = 33.1 bits (74), Expect = 0.54
 Identities = 49/154 (31%), Positives = 55/154 (35%), Gaps = 28/154 (18%)

Query: 49   TGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGP--RRG-----GLRSRTD 101
            TGA      PG   +    G  G + +R  A + G    + GP   RG     G R    
Sbjct: 992  TGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS-GPAGARGIQGPQGPRGDKG 1050

Query: 102  PAFGAGPLPLVSRLGHAGERGSPG-------AGDVNPVSASSPPGRPDPLLLTTFVFPPG 154
             A   G   L    G  G +G PG        G   P   S P G P P      V P G
Sbjct: 1051 EAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP------VGPSG 1104

Query: 155  KTSA---PRP-SPGGRRGR--PLGAARGTGLNPG 182
            K  A   P P  P G RGR    G A   G NPG
Sbjct: 1105 KDGANGIPGPIGPPGPRGRSGETGPAGPPG-NPG 1137


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 65.5 bits (158), Expect = 1e-10
 Identities = 99/322 (30%), Positives = 116/322 (36%), Gaps = 58/322 (18%)

Query: 56   PTPGRARAAP-QQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSR 114
            P P     AP Q G+ G + ER A    G          GG      P  G+GP      
Sbjct: 806  PGPAGFPGAPGQNGEPGGKGERGAPGEKG---------EGGPPGVAGPPGGSGPAGPPGP 856

Query: 115  LGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPGGRRGR--PL 171
             G  GERGSPG     P +A  P  R  P        PPG    P  P P G  G+  P 
Sbjct: 857  QGVKGERGSPG----GPGAAGFPGARGLP-------GPPGSNGNPGPPGPSGSPGKDGPP 905

Query: 172  GAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAP--------SRRRNFGAPR 223
            G A  TG  PG SP +  P+G  + +  +  S        AP        +  R    P 
Sbjct: 906  GPAGNTGA-PG-SPGVSGPKG-DAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPP 962

Query: 224  GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGP--RSRLPGLAGGVEPPGWSRERAG 281
            G     P     P   G KG+        L+  RGP     LPGLAG    PG       
Sbjct: 963  G----MPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018

Query: 282  AGL-SRD-SP----QVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATE 335
             GL  RD SP        +GS   P    GHP       PA  S  R  +   GP GA  
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAP-GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPG 1077

Query: 336  PGFVTLAFRSRLPLLRSPGPEG 357
            P        SR     +PGP+G
Sbjct: 1078 PA------GSR----GAPGPQG 1089



 Score = 63.5 bits (153), Expect = 4e-10
 Identities = 98/355 (27%), Positives = 114/355 (32%), Gaps = 46/355 (12%)

Query: 45  SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
           +P   G A  +  PG    A ++G  G    R AA   G      GP   G+R       
Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP---GMRGMPGSPG 543

Query: 105 GAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPG 164
           G G        G  GE G PG     P   S P G+P         FP  K +   P   
Sbjct: 544 GPGSDGKPGPPGSQGESGRPG-----PPGPSGPRGQPG-----VMGFPGPKGNDGAPGKN 593

Query: 165 GRRGRP--LGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP 222
           G RG P   G     G N    P+           + DT        +  P      G P
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT----GGP 649

Query: 223 RGSRRL------RPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWS 276
            G          + DAG  P A GGKG   A  ER    G    +  PGL GG  PPG  
Sbjct: 650 PGENGKPGEPGPKGDAGA-PGAPGGKGDAGAPGER----GPPGLAGAPGLRGGAGPPGPE 704

Query: 277 RERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEP 336
             +  AG           G    P    G      L SP P           GPG    P
Sbjct: 705 GGKGAAGPPGPPGAAGTPGLQGMPGERGG------LGSPGPKG---DKGEPGGPGADGVP 755

Query: 337 GFVTLAFRSRLPLLRSPGPEG-TSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSG 390
           G      R     +  PGP G   D     APGL       A PR  P +R  +G
Sbjct: 756 G--KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG----IAGPRGSPGERGETG 804



 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 96/357 (26%), Positives = 120/357 (33%), Gaps = 45/357 (12%)

Query: 46  PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
           P   GA       G    A   G  GA+ E     S G   A   P   G R        
Sbjct: 434 PGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP 493

Query: 106 AGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRP----DPLLLTTFVFPPGKTSAPRP 161
           AGP  +    G AGERG+P  G   P  A+  PGR      P +      P G  S  +P
Sbjct: 494 AGPNGIPGEKGPAGERGAP--GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551

Query: 162 SPGGRRGR-----PLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRR 216
            P G +G      P G +   G  PG+      P+G+                  AP + 
Sbjct: 552 GPPGSQGESGRPGPPGPSGPRG-QPGVM-GFPGPKGNDG----------------APGKN 593

Query: 217 RNFGAPRGSRRLRPDAGKFPEA--SGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPG 274
              G P G     P  GK  E    G  G    G ++      GP+  L GL G   PPG
Sbjct: 594 GERGGPGGPGPQGP-PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQG-LQGLPGTGGPPG 651

Query: 275 WSRERAGAGLSRD--SPQVPRSGSWARPCREQGHPAVLALQS-------PAPPSLARAAA 325
            + +    G   D  +P  P     A    E+G P +            P P     AA 
Sbjct: 652 ENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAG 711

Query: 326 RRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAP-APGLRDRDLRAAPPRP 381
               PG A  PG   +        L SPGP+G       P A G+  +D    P  P
Sbjct: 712 PPGPPGAAGTPGLQGMP--GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGP 766



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 86/293 (29%), Positives = 104/293 (35%), Gaps = 47/293 (16%)

Query: 94  GGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTF 149
           GGL     PA   GP       GH G  GSPG     G+      S PPG P        
Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGA------ 220

Query: 150 VFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLS-----PRLQEPRGH-----QSARRT 199
           + P G   A +    GR GRP    RG    PG+      P     +GH     ++  + 
Sbjct: 221 IGPSG--PAGKDGESGRPGRP--GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 200 DTASRAGWATRRAPSRRRNFG--APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGR 257
           +T +         P      G   PRG+   R   G  P A+G +G   A          
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG-LPGAAGARGNDGARGSDGQPGPP 335

Query: 258 GPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAP 317
           GP    PG AG    PG   E   AG S  S   P       P   QGH    A   P P
Sbjct: 336 GP----PGTAGFPGSPGAKGEVGPAG-SPGSNGAPGQRGEPGP---QGHAG--AQGPPGP 385

Query: 318 PSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLR 370
           P +  +   +   G A  PG   L   +R P    PGP G +      APGLR
Sbjct: 386 PGINGSPGGKGEMGPAGIPGAPGL-MGARGP----PGPAGANG-----APGLR 428



 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 84/337 (24%), Positives = 108/337 (32%), Gaps = 50/337 (14%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
           GAA     PG A     QG  G R    +    G +    GP   G+  +  P    GP+
Sbjct: 708 GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 110 PLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP--RPSPGGRR 167
                 G  G++G  GA  +  +  + P G P     T    P G   AP     PGG+ 
Sbjct: 768 GPPGPAGQPGDKGEGGAPGLPGI--AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG 825

Query: 168 GRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRR 227
            R     +G G  PG+                  A   G +    P   +     RGS  
Sbjct: 826 ERGAPGEKGEGGPPGV------------------AGPPGGSGPAGPPGPQGVKGERGSPG 867

Query: 228 LRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRD 287
             P A  FP A G  G   +      N G    S  PG  G   P G +      G+S  
Sbjct: 868 -GPGAAGFPGARGLPGPPGSNG----NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGP 922

Query: 288 SPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARR--RGPGGATEPGFVTLAFRS 345
                + G    P   QG P      +P P  +A     R   GP G   P         
Sbjct: 923 KGDAGQPGEKGSP-GAQGPPG-----APGPLGIAGITGARGLAGPPGMPGP--------- 967

Query: 346 RLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPR 382
                 SPGP+G      +  PG         PP P+
Sbjct: 968 ----RGSPGPQGVK--GESGKPGANGLSGERGPPGPQ 998



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 89/343 (25%), Positives = 111/343 (32%), Gaps = 66/343 (19%)

Query: 58  PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
           PG A      G  G      +  S G Q     P + G      P    GP     + G 
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232

Query: 118 AGERGSPG-AGDVNPVSASSPPGRPD-PLLLTTFVF-----PPGKTSAP----------- 159
           +G  G PG  G   P     P G P  P +     F       G+T AP           
Sbjct: 233 SGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGE 292

Query: 160 --RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRR 217
              P P G RG P     G    PGL P     RG+  AR +D     G      P    
Sbjct: 293 NGAPGPMGPRGAP-----GERGRPGL-PGAAGARGNDGARGSD-----GQPGPPGPPGTA 341

Query: 218 NFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSR 277
            F    G++     AG  P ++G  GQR     +     +GP    PG  G    PG   
Sbjct: 342 GFPGSPGAKGEVGPAGS-PGSNGAPGQRGEPGPQGHAGAQGP----PGPPGINGSPGGKG 396

Query: 278 ERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPG 337
           E   AG+                    G P ++  + P  P+ A  A   R  GGA EPG
Sbjct: 397 EMGPAGI-------------------PGAPGLMGARGPPGPAGANGAPGLR--GGAGEPG 435

Query: 338 FVTLAFRSRLPLLRSPGPEGTSDAARAP-APGLRDRDLRAAPP 379
                   +      PGP G    A  P  PG +  D +   P
Sbjct: 436 --------KNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 93/354 (26%), Positives = 117/354 (33%), Gaps = 64/354 (18%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
           GA      PG   AA  +G+ GAR         G       P   G +    PA   G  
Sbjct: 303 GAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG-- 360

Query: 110 PLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGR 169
                 G  G+RG P  G      A  PPG            PPG       SPGG+   
Sbjct: 361 ----SNGAPGQRGEP--GPQGHAGAQGPPG------------PPGING----SPGGK--- 395

Query: 170 PLGAARGTGLNPGLSPRLQEPRGHQS-ARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL 228
             G     G+ PG +P L   RG    A         G A     +  +    PRG R  
Sbjct: 396 --GEMGPAGI-PG-APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGE 451

Query: 229 RPDAGKFPEASGGKGQRAAGAERVLNN--GRGPRSRLPGLAGGVEPPGWSRERAGAG-LS 285
               G  P A G  G+  +  E   N   G       PG  G   P G   E+  AG   
Sbjct: 452 AGIPG-VPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510

Query: 286 RDSPQVPRSGSWARPCRE--QGHPAVLALQ----------SPAPPSLARAAARRRGPGGA 333
              P  PR G+   P R+   G P +  +            P PP  ++  + R GP G 
Sbjct: 511 APGPAGPR-GAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG-SQGESGRPGPPGP 568

Query: 334 TEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRP 387
           + P       R +  ++  PGP+G        APG      R  P  P P   P
Sbjct: 569 SGP-------RGQPGVMGFPGPKGNDG-----APGKNGE--RGGPGGPGPQGPP 608



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 83/307 (27%), Positives = 99/307 (32%), Gaps = 42/307 (13%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
            SP V+G    +  PG   +   QG  GA      A   G +     P   G R    P  
Sbjct: 916  SPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975

Query: 105  GAGPLPLVSRLGHAGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP--RP 161
              G        G +GERG PG  G       +  PGR            PG    P    
Sbjct: 976  VKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG---------NPGSDGLPGRDG 1026

Query: 162  SPGGRRGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF 219
            SPGG+  R    + G    PG    P    P G    R    +  AG A    P+  R  
Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDR--GESGPAGPAGAPGPAGSRGA 1084

Query: 220  GAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSR-----LPGLAGGVEPPG 274
              P+G R  + + G+   A+G KG R            GP  +      PG AG   P G
Sbjct: 1085 PGPQGPRGDKGETGE-RGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143

Query: 275  WSRERAGAGLSRD----SPQVPRSGSWARPCR-EQGHPAVLALQSPAPPSLARAAARRRG 329
             S      G S       P  PR     R      GHP       P PP          G
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPG-----QPGPP----------G 1188

Query: 330  PGGATEP 336
            P GA  P
Sbjct: 1189 PPGAPGP 1195



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 74/296 (25%), Positives = 91/296 (30%), Gaps = 31/296 (10%)

Query: 46  PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
           P   G        G    A   G  GA  +R      G   A   P   G+         
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGE 397

Query: 106 AGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPG 164
            GP  +    G  G RG PG     P  A+  PG      L      PGK  A   P P 
Sbjct: 398 MGPAGIPGAPGLMGARGPPG-----PAGANGAPG------LRGGAGEPGKNGAKGEPGPR 446

Query: 165 GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
           G RG         G+ PG+     E     S          G A  R     R    P G
Sbjct: 447 GERGE-------AGI-PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498

Query: 225 SRRLRPDAGK--FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGA 282
               +  AG+   P  +G +G         +  G G R  +PG  GG   PG   +    
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG-MPGSPGG---PGSDGKPGPP 554

Query: 283 GLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAA-ARRRGPGGATEPG 337
           G   +S +    G    P   +G P V+    P     A      R GPGG    G
Sbjct: 555 GSQGESGRPGPPG----PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 43/151 (28%), Positives = 52/151 (34%), Gaps = 43/151 (28%)

Query: 55   SPTPGRARAAP----QQGDGGARRERAAAE------------------SLGTQSATLGPR 92
            +P P  +R AP     +GD G   ER AA                     G Q A   P 
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134

Query: 93   RGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA----GDVNPVSASSPPGRPDPLLLTT 148
              G R    P+   GP       GH G  G PG     G+     +   PG+P P     
Sbjct: 1135 PAGPRGPVGPS---GPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGP----- 1186

Query: 149  FVFPPGKTSAPRPSPGGRRGRPLGAARGTGL 179
                PG   AP P  GG     +GAA   G+
Sbjct: 1187 ----PGPPGAPGPCCGG-----VGAAAIAGI 1208


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 63.9 bits (154), Expect = 3e-10
 Identities = 99/370 (26%), Positives = 126/370 (34%), Gaps = 64/370 (17%)

Query: 57  TPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLG 116
           +PG   A  Q G  G   ER    + G   A       G      P   AGP      +G
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVG 350

Query: 117 HAGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPG-GRRGRPLGAA 174
             GE G  G  G   P      PG            PPG   A  P+   G  G+P   A
Sbjct: 351 AKGEAGPQGPRGSEGPQGVRGEPG------------PPGPAGAAGPAGNPGADGQP--GA 396

Query: 175 RGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGK 234
           +G    PG+                  A   G+   R PS  +  G P G    + ++G+
Sbjct: 397 KGANGAPGI------------------AGAPGFPGARGPSGPQGPGGPPGP---KGNSGE 435

Query: 235 FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRS 294
            P A G KG   A  E      +GP    PG AG     G   E    GL    P   R 
Sbjct: 436 -PGAPGSKGDTGAKGEPGPVGVQGP----PGPAGEEGKRGARGEPGPTGL--PGPPGERG 488

Query: 295 GSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLR--- 351
           G  +R     G P    +  P  P+  R +    GP G+  PG       + LP  +   
Sbjct: 489 GPGSR-----GFPGADGVAGPKGPAGERGSPGPAGPKGS--PGEAGRPGEAGLPGAKGLT 541

Query: 352 ----SPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSA 407
               SPGP+G     +   PG   +D R  PP P P  R  +G+         +G    A
Sbjct: 542 GSPGSPGPDG-----KTGPPGPAGQDGRPGPPGP-PGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 408 CEVAVPTTAG 417
            E  VP   G
Sbjct: 596 GERGVPGPPG 605



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 117/424 (27%), Positives = 140/424 (33%), Gaps = 69/424 (16%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF--GA- 106
           G A    +PG A    + G  GA+    +  S G    T  P   G   R  P    GA 
Sbjct: 515 GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 107 ---------GPLPLVSRLGHAGERGSPG-------AGDVNPVSASSPPGRPDPLLLTTFV 150
                    GP       G AGERG PG       AG      A  PPG   P       
Sbjct: 575 GQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634

Query: 151 FP---PGKTSAPRPS-PGGRRGRP--------LGA-----ARGTGLNPGL-----SPRLQ 188
            P   PG    P P+ P G  G+P        LGA     ARG    PG       P   
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA 694

Query: 189 EPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP--RGSRRLRPDAGKFPEASGGKGQRA 246
            PRG   A   D A         AP    + GAP  +G    R  AG      G KG R 
Sbjct: 695 GPRGANGAPGNDGAK----GDAGAPGAPGSQGAPGLQGMPGERGAAG----LPGPKGDRG 746

Query: 247 AGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGH 306
               +  +   G +  + GL G + PPG +      G S  S     +G+   P  ++G 
Sbjct: 747 DAGPKGADGSPG-KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP-GDRGE 804

Query: 307 PAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSP-GPEGTSDAARAP 365
           P       P P   A        PG   EPG       +  P    P GP G        
Sbjct: 805 PG-----PPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPG--PIGNVG 857

Query: 366 APGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAGRELLGSEP 425
           APG +     A PP         +G       V   GP  +A     P  AG+E  G  P
Sbjct: 858 APGAKGARGSAGPP-------GATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE-GGKGP 909

Query: 426 RNGT 429
           R  T
Sbjct: 910 RGET 913



 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 98/337 (29%), Positives = 118/337 (35%), Gaps = 68/337 (20%)

Query: 45  SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
           +P   GA      PG   AA   G  G R +       G + A   P + G+R  T P  
Sbjct: 717 APGSQGAPGLQGMPGERGAAGLPGPKGDRGDA------GPKGADGSPGKDGVRGLTGPIG 770

Query: 105 GAGPLPLVSRLGHAGERGSPG-AGDVNPVSASSPP---GRPDPLLLTTFVFPPGKTSAPR 160
             GP       G  G++G  G +G   P  A   P   G P P     F  PPG    P 
Sbjct: 771 PPGP------AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP- 823

Query: 161 PSPGGRRGRPLGA-ARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF 219
               G +G P  A A+G    PG                   A  AG      P    N 
Sbjct: 824 ----GAKGEPGDAGAKGDAGPPG------------------PAGPAG-----PPGPIGNV 856

Query: 220 GAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRER 279
           GAP G++  R  AG  P A+G  G  AAG  RV     GP     G AG   PPG + + 
Sbjct: 857 GAP-GAKGARGSAGP-PGATGFPG--AAG--RV--GPPGP----SGNAGPPGPPGPAGKE 904

Query: 280 AGAGLSRDSPQVPRSGSWA-----RPCREQGHPA----VLALQSPAPPSLARAAARRRGP 330
            G G   ++    R G         P  E+G P       A  +P P  +A        P
Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 331 GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
           G   E GF  L   S  P     GP G S     P P
Sbjct: 965 GQRGERGFPGLPGPSGEP--GKQGPSGASGERGPPGP 999



 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 87/328 (26%), Positives = 105/328 (32%), Gaps = 31/328 (9%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
           GA   +  PG A A    G  G    +      G +  +  P   G +  T      GP+
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454

Query: 110 PLVSRLGHAGERGSPGA-GDVNPVSASSPPG-RPDPLLLTTFVFPPGKTSAPRPSPGGRR 167
            +    G AGE G  GA G+  P     PPG R  P    +  FP     A    P G R
Sbjct: 455 GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGP---GSRGFPGADGVAGPKGPAGER 511

Query: 168 GRPLGAARGTGLNPGLSPRLQE---PRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
           G P G A   G +PG + R  E   P          +    G      P+ +     P G
Sbjct: 512 GSP-GPAGPKG-SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPG 569

Query: 225 SRRLRPDAG--KFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGA 282
               R  AG   FP   G  G+     ER           +PG  G V P G   E    
Sbjct: 570 PPGARGQAGVMGFPGPKGAAGEPGKAGER----------GVPGPPGAVGPAGKDGEAGAQ 619

Query: 283 GLSRDSPQVPRSGSWARPCREQGHPAVLALQSPA-PPSLARAAARRRGPGGATEPGFVTL 341
           G    +      G         G P    L  PA PP  A     +  PG    PG    
Sbjct: 620 GPPGPAGPAGERGEQG----PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGA 675

Query: 342 AFRSRLPLLRS----PGPEGTSDAARAP 365
                 P  R     PGP G   A  AP
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAP 703



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 109/425 (25%), Positives = 131/425 (30%), Gaps = 75/425 (17%)

Query: 64  APQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGS 123
           A ++G  GAR E       G      GP   G       A   GP       G AG +GS
Sbjct: 463 AGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522

Query: 124 PG-------AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPGGRRGR------ 169
           PG       AG       +  PG P P   T    P G+   P  P P G RG+      
Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582

Query: 170 --PLGAA--------RGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF 219
             P GAA        RG    PG      +     +      A  AG    + P+    F
Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF 642

Query: 220 GAPRGSRRLRPDAGK-----------FPEASGGKGQRAAGAERVLNNGRGPR-------- 260
               G      +AGK            P  SG +G+R    ER +    GP         
Sbjct: 643 QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGA 702

Query: 261 ---------SRLPGLAGGVEPP---GWSRERAGAGLSRDSPQVPRSGSWARPCREQGHP- 307
                    +  PG  G    P   G   ER  AGL    P+  R    A P    G P 
Sbjct: 703 PGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL--PGPKGDRGD--AGPKGADGSPG 758

Query: 308 --AVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAP 365
              V  L  P  P     A   +G  G + P   T A R        PGP G +  A  P
Sbjct: 759 KDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA-RGAPGDRGEPGPPGPAGFAGPP 817

Query: 366 A----------PGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAV--P 413
                      PG       A PP P     P   +  V     +   GS+    A   P
Sbjct: 818 GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP 877

Query: 414 TTAGR 418
             AGR
Sbjct: 878 GAAGR 882



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 81/294 (27%), Positives = 97/294 (32%), Gaps = 49/294 (16%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
            SP   G A    TPG    A Q+G  G   +R      G    +  P + G    +    
Sbjct: 936  SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995

Query: 105  GAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPG 164
              GP+      G  GE G  GA       A   PGR           P  K       P 
Sbjct: 996  PPGPMGPPGLAGPPGESGREGA-----PGAEGSPGRDGS--------PGAKGDRGETGPA 1042

Query: 165  GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
            G  G P GA       PG +P    P G +S  R +T   AG A    P   R    P+G
Sbjct: 1043 GPPGAP-GA-------PG-APGPVGPAG-KSGDRGETGP-AGPAGPVGPVGARGPAGPQG 1091

Query: 225  SRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGL 284
             R             G KG+     +R +   RG      GL G   PPG   E+  +G 
Sbjct: 1092 PR-------------GDKGETGEQGDRGIKGHRG----FSGLQGPPGPPGSPGEQGPSGA 1134

Query: 285  SRDSPQVPRS--GSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEP 336
            S   P  PR   GS   P    G   +  L  P  P   R      GP G   P
Sbjct: 1135 S--GPAGPRGPPGSAGAP----GKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGP 1182



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 26/88 (29%), Positives = 30/88 (34%), Gaps = 10/88 (11%)

Query: 66   QQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG 125
            +QGD G +  R  +   G       P   G    + PA   GP       G  G  G PG
Sbjct: 1101 EQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPG 1160

Query: 126  ----------AGDVNPVSASSPPGRPDP 143
                       GD  PV    PPG P P
Sbjct: 1161 PIGPPGPRGRTGDAGPVGPPGPPGPPGP 1188


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 109/403 (27%), Positives = 148/403 (36%), Gaps = 101/403 (25%)

Query: 29  RRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSAT 88
           RR+     GS+ +  LS H + +  RSP+    R +P+  D G  R+  +  S G++S +
Sbjct: 250 RRSHRHSSGSSHSPSLSSHYSDS--RSPS----RLSPKHRDEG--RKTGSQRSSGSRSPS 301

Query: 89  LGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGER-----GSPGAGDVNPVSASSPPGRPDP 143
                        P+ G+G      R G +G+R     G PG+    P   SSP  R   
Sbjct: 302 -------------PSGGSG-WGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRD 347

Query: 144 LLLTTFVFPP--GKTS-APR--PSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARR 198
                   PP  GK S +PR  PS  GR GR   AA G G            R  +  RR
Sbjct: 348 KAAAAAPTPPARGKESPSPRSAPSSQGRGGR---AAGGAG------------RRRRRRRR 392

Query: 199 TDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRG 258
              +  +  A RR   RR     PRGS R    A    ++  G+G    G E     G G
Sbjct: 393 RRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHG 452

Query: 259 ----------PRSR------LPGLAG--------------GVEPPGWSRERA-GAGLSRD 287
                     PR+R       PG  G              G  P  WS  R+     SR 
Sbjct: 453 GHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRS 512

Query: 288 SPQVP----RSGSWARPCREQGHPAVLALQSPAPPSLARAAA--------RRRGPGGATE 335
           + + P    RS S  +P          A  S A  + AR  +        RRR      E
Sbjct: 513 AEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRDSPSFME 572

Query: 336 PGFVTLAFRSRLPLLRSPGPEGTSDA----------ARAPAPG 368
           P  +T A +  +P  R P P  +S            +R+P+PG
Sbjct: 573 PRRITSARKRPIPYYR-PSPSSSSSCLSSDYSTRSHSRSPSPG 614



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 46/195 (23%), Positives = 61/195 (31%), Gaps = 4/195 (2%)

Query: 4   RAAAESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARA 63
           R    SR   +  R     RP     R  S     A +   S    GA    P PG  R 
Sbjct: 391 RRRRRSRSSASAPRRRGRRRPRPAPPRGSSRSLSRARSSSDSGSGRGAPGPGPEPGSERG 450

Query: 64  APQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGS 123
               G     R   A  +  + S     RRGG   ++  +   GP P       +  +  
Sbjct: 451 HGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSS-SRSPGPHPRSWSSSRSPSKSR 509

Query: 124 PGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGL 183
             + +  P S S  P    PL          + S    +   RR R     R    +   
Sbjct: 510 SRSAEKRPHSPSRSPSPKKPLSRDKDGEGRARHSEAEATRARRRSRSYSPIRKRRRD--- 566

Query: 184 SPRLQEPRGHQSARR 198
           SP   EPR   SAR+
Sbjct: 567 SPSFMEPRRITSARK 581


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 86/332 (25%), Positives = 105/332 (31%), Gaps = 39/332 (11%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
            G A     PG A      G GG + ER      G   A   P   G      P    GP+
Sbjct: 1270 GEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 110  PLVSRLGHAGERGSPGAGDV-NPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRG 168
                  G  GE G  G   V         PG+P P        P     A  P P G+RG
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP--------PGPSGEAGPPGPPGKRG 1375

Query: 169  RPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL 228
             P GAA   G   G      E        +T      G A +  P   R    P G + L
Sbjct: 1376 PP-GAAGAEG-RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1433

Query: 229  RPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL--PGLAGGVEPPGWSRERAGAGL-- 284
               AG+     G  G         L    G +     PGL G + PPG   E+   GL  
Sbjct: 1434 PGAAGQ----DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 285  SRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRG----------PGGAT 334
            ++ SP     G    P    G P    L  P  P   + +    G          PG   
Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 335  EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPA 366
             PG V       LP+L S      ++  +A A
Sbjct: 1550 PPGEVI----QPLPILSSKKTRRHTEGMQADA 1577



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 100/381 (26%), Positives = 130/381 (34%), Gaps = 70/381 (18%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-----------RG 94
            P + G       PG      Q G+ GA         +G      GPR           +G
Sbjct: 732  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP----GPRGVKGADGVRGLKG 787

Query: 95   GLRSRTDPAFGA--GPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVF 151
                + +  F    G + L    G  G+ G  G  G   P   + P G P P   +    
Sbjct: 788  SKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP---SGQAG 844

Query: 152  PPGKTSAPR-PSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATR 210
              GK   P  P   GR+G P G+    G  PG +       G + AR        G A +
Sbjct: 845  EKGKLGVPGLPGYPGRQG-PKGSTGFPGF-PGAN-------GEKGAR--------GVAGK 887

Query: 211  RAPSRRRNFGAPRGSRRLRPDAGK-FPE-ASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
              P  +R    PRGSR  R   GK  P+  SGG G      ER     +GP    PG  G
Sbjct: 888  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG-FPGPKG 946

Query: 269  GVEP------PGWSRERAGAGLSRDS----------PQVPRSGSWARPCREQGHPAVLAL 312
               P      PG   +R   G    +          PQ P   +   P  E+GHP     
Sbjct: 947  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET--GPIGERGHPG---- 1000

Query: 313  QSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRS-PGPEGTSDAARAPAPGLRD 371
              P PP            G   +PG   ++ +     LR  PG  G   A    APGL+ 
Sbjct: 1001 -PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA--QGAPGLKG 1057

Query: 372  RDLRAAPPRP--RPSQRPVSG 390
             +    PP P   P +R  +G
Sbjct: 1058 GEGPQGPPGPVGSPGERGSAG 1078



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 89/334 (26%), Positives = 111/334 (33%), Gaps = 63/334 (18%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG-------AGPLPLVSRLGHAGE 120
           GD G R ER      G Q     P   G+R   D   G       AGP  L+   G  G 
Sbjct: 622 GDKGHRGER------GPQGPPGPPGDDGMRGE-DGEIGPRGLPGEAGPRGLLGPRGTPGA 674

Query: 121 RGSPGAGDVN----PVSASSPPGRPDPLLLTTFVFPPGKTSAP----RPSPGGRRGRPLG 172
            G PG   V+    P     P G P          PPG+   P     P P G  G P  
Sbjct: 675 PGQPGMAGVDGPPGPKGNMGPQGEPG---------PPGQQGNPGPQGLPGPQGPIGPP-- 723

Query: 173 AARGTGLNPGLS--PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR------G 224
             +G    PGL+  P    P GH    +   +   G      P     +  PR      G
Sbjct: 724 GEKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG 781

Query: 225 SRRLRPDAGK-----FPEASGGKGQRAAGAE------RVLNNGRGPRSRLPGLAGGVEPP 273
            R L+   G+     FP   G  G +    E      R  +   GP+ R  G  G   P 
Sbjct: 782 VRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR-AGPTGDPGPS 840

Query: 274 GWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGA 333
           G + E+   G+    P +P       P    G P             AR  A + GP G 
Sbjct: 841 GQAGEKGKLGV----PGLPGYPGRQGPKGSTGFPGFPGANGEKG---ARGVAGKPGPRGQ 893

Query: 334 TEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
             P     +  +R P    PGP+GTS     P P
Sbjct: 894 RGPTGPRGSRGARGP-TGKPGPKGTSGGDGPPGP 926



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 89/373 (23%), Positives = 117/373 (31%), Gaps = 76/373 (20%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-RGGLRSRTDPA 103
            SP   G+A  +   G       QG  G   E+ A    G Q    GP  R G++      
Sbjct: 1070 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ----GPAGRDGVQGPVGLP 1125

Query: 104  FGAGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS 162
              AGP       G  GE G PG  G       + PPG            PPG        
Sbjct: 1126 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG------------PPGLQ------ 1167

Query: 163  PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQS--ARRTDTASRAGWATRRAPSRRRNFG 220
              G  G P G A G G  PG       PRG Q    ++ D  +R G+     P   +   
Sbjct: 1168 --GPVGAP-GIAGGDG-EPG-------PRGQQGMFGQKGDEGAR-GFPGPPGPIGLQGLP 1215

Query: 221  APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL-----------PGLAGG 269
             P G +    D G      G  G R        +  +GP   +           PG AG 
Sbjct: 1216 GPPGEKGENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274

Query: 270  VEPPGWSRERAGAGLSRDSPQVPRSGSWARPCRE--------QGHPAVLALQSPAPPSLA 321
              PPG +      G   +  +    G+   P  +        +G+P  +       P   
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334

Query: 322  RAAARRRGPGGAT----EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAA 377
               A + G GG      +PG               PGP G S  A  P P  +     AA
Sbjct: 1335 PGPAGQDGVGGDKGEDGDPG--------------QPGPPGPSGEAGPPGPPGKRGPPGAA 1380

Query: 378  PPRPRPSQRPVSG 390
                R  ++   G
Sbjct: 1381 GAEGRQGEKGAKG 1393


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 86/332 (25%), Positives = 105/332 (31%), Gaps = 39/332 (11%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
            G A     PG A      G GG + ER      G   A   P   G      P    GP+
Sbjct: 1219 GEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 110  PLVSRLGHAGERGSPGAGDV-NPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRG 168
                  G  GE G  G   V         PG+P P        P     A  P P G+RG
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP--------PGPSGEAGPPGPPGKRG 1324

Query: 169  RPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL 228
             P GAA   G   G      E        +T      G A +  P   R    P G + L
Sbjct: 1325 PP-GAAGAEG-RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1382

Query: 229  RPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL--PGLAGGVEPPGWSRERAGAGL-- 284
               AG+     G  G         L    G +     PGL G + PPG   E+   GL  
Sbjct: 1383 PGAAGQ----DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 285  SRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRG----------PGGAT 334
            ++ SP     G    P    G P    L  P  P   + +    G          PG   
Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 335  EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPA 366
             PG V       LP+L S      ++  +A A
Sbjct: 1499 PPGEVI----QPLPILSSKKTRRHTEGMQADA 1526



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 100/381 (26%), Positives = 130/381 (34%), Gaps = 70/381 (18%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-----------RG 94
            P + G       PG      Q G+ GA         +G      GPR           +G
Sbjct: 681  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP----GPRGVKGADGVRGLKG 736

Query: 95   GLRSRTDPAFGA--GPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVF 151
                + +  F    G + L    G  G+ G  G  G   P   + P G P P   +    
Sbjct: 737  SKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP---SGQAG 793

Query: 152  PPGKTSAPR-PSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATR 210
              GK   P  P   GR+G P G+    G  PG +       G + AR        G A +
Sbjct: 794  EKGKLGVPGLPGYPGRQG-PKGSTGFPGF-PGAN-------GEKGAR--------GVAGK 836

Query: 211  RAPSRRRNFGAPRGSRRLRPDAGK-FPE-ASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
              P  +R    PRGSR  R   GK  P+  SGG G      ER     +GP    PG  G
Sbjct: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG-FPGPKG 895

Query: 269  GVEP------PGWSRERAGAGLSRDS----------PQVPRSGSWARPCREQGHPAVLAL 312
               P      PG   +R   G    +          PQ P   +   P  E+GHP     
Sbjct: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET--GPIGERGHPG---- 949

Query: 313  QSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRS-PGPEGTSDAARAPAPGLRD 371
              P PP            G   +PG   ++ +     LR  PG  G   A    APGL+ 
Sbjct: 950  -PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA--QGAPGLKG 1006

Query: 372  RDLRAAPPRP--RPSQRPVSG 390
             +    PP P   P +R  +G
Sbjct: 1007 GEGPQGPPGPVGSPGERGSAG 1027



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 89/334 (26%), Positives = 111/334 (33%), Gaps = 63/334 (18%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG-------AGPLPLVSRLGHAGE 120
           GD G R ER      G Q     P   G+R   D   G       AGP  L+   G  G 
Sbjct: 571 GDKGHRGER------GPQGPPGPPGDDGMRGE-DGEIGPRGLPGEAGPRGLLGPRGTPGA 623

Query: 121 RGSPGAGDVN----PVSASSPPGRPDPLLLTTFVFPPGKTSAP----RPSPGGRRGRPLG 172
            G PG   V+    P     P G P          PPG+   P     P P G  G P  
Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPG---------PPGQQGNPGPQGLPGPQGPIGPP-- 672

Query: 173 AARGTGLNPGLS--PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR------G 224
             +G    PGL+  P    P GH    +   +   G      P     +  PR      G
Sbjct: 673 GEKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG 730

Query: 225 SRRLRPDAGK-----FPEASGGKGQRAAGAE------RVLNNGRGPRSRLPGLAGGVEPP 273
            R L+   G+     FP   G  G +    E      R  +   GP+ R  G  G   P 
Sbjct: 731 VRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR-AGPTGDPGPS 789

Query: 274 GWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGA 333
           G + E+   G+    P +P       P    G P             AR  A + GP G 
Sbjct: 790 GQAGEKGKLGV----PGLPGYPGRQGPKGSTGFPGFPGANGEKG---ARGVAGKPGPRGQ 842

Query: 334 TEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
             P     +  +R P    PGP+GTS     P P
Sbjct: 843 RGPTGPRGSRGARGP-TGKPGPKGTSGGDGPPGP 875



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 89/373 (23%), Positives = 117/373 (31%), Gaps = 76/373 (20%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-RGGLRSRTDPA 103
            SP   G+A  +   G       QG  G   E+ A    G Q    GP  R G++      
Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ----GPAGRDGVQGPVGLP 1074

Query: 104  FGAGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS 162
              AGP       G  GE G PG  G       + PPG            PPG        
Sbjct: 1075 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG------------PPGLQ------ 1116

Query: 163  PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQS--ARRTDTASRAGWATRRAPSRRRNFG 220
              G  G P G A G G  PG       PRG Q    ++ D  +R G+     P   +   
Sbjct: 1117 --GPVGAP-GIAGGDG-EPG-------PRGQQGMFGQKGDEGAR-GFPGPPGPIGLQGLP 1164

Query: 221  APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL-----------PGLAGG 269
             P G +    D G      G  G R        +  +GP   +           PG AG 
Sbjct: 1165 GPPGEKGENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223

Query: 270  VEPPGWSRERAGAGLSRDSPQVPRSGSWARPCRE--------QGHPAVLALQSPAPPSLA 321
              PPG +      G   +  +    G+   P  +        +G+P  +       P   
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283

Query: 322  RAAARRRGPGGAT----EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAA 377
               A + G GG      +PG               PGP G S  A  P P  +     AA
Sbjct: 1284 PGPAGQDGVGGDKGEDGDPG--------------QPGPPGPSGEAGPPGPPGKRGPPGAA 1329

Query: 378  PPRPRPSQRPVSG 390
                R  ++   G
Sbjct: 1330 GAEGRQGEKGAKG 1342


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 57.8 bits (138), Expect = 2e-08
 Identities = 86/332 (25%), Positives = 105/332 (31%), Gaps = 39/332 (11%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
            G A     PG A      G GG + ER      G   A   P   G      P    GP+
Sbjct: 1258 GEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 110  PLVSRLGHAGERGSPGAGDV-NPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRG 168
                  G  GE G  G   V         PG+P P        P     A  P P G+RG
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP--------PGPSGEAGPPGPPGKRG 1363

Query: 169  RPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL 228
             P GAA   G   G      E        +T      G A +  P   R    P G + L
Sbjct: 1364 PP-GAAGAEG-RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL 1421

Query: 229  RPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL--PGLAGGVEPPGWSRERAGAGL-- 284
               AG+     G  G         L    G +     PGL G + PPG   E+   GL  
Sbjct: 1422 PGAAGQ----DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 285  SRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRG----------PGGAT 334
            ++ SP     G    P    G P    L  P  P   + +    G          PG   
Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 335  EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPA 366
             PG V       LP+L S      ++  +A A
Sbjct: 1538 PPGEVI----QPLPILSSKKTRRHTEGMQADA 1565



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 100/381 (26%), Positives = 130/381 (34%), Gaps = 70/381 (18%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-----------RG 94
            P + G       PG      Q G+ GA         +G      GPR           +G
Sbjct: 720  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP----GPRGVKGADGVRGLKG 775

Query: 95   GLRSRTDPAFGA--GPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVF 151
                + +  F    G + L    G  G+ G  G  G   P   + P G P P   +    
Sbjct: 776  SKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP---SGQAG 832

Query: 152  PPGKTSAPR-PSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATR 210
              GK   P  P   GR+G P G+    G  PG +       G + AR        G A +
Sbjct: 833  EKGKLGVPGLPGYPGRQG-PKGSTGFPGF-PGAN-------GEKGAR--------GVAGK 875

Query: 211  RAPSRRRNFGAPRGSRRLRPDAGK-FPE-ASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
              P  +R    PRGSR  R   GK  P+  SGG G      ER     +GP    PG  G
Sbjct: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG-FPGPKG 934

Query: 269  GVEP------PGWSRERAGAGLSRDS----------PQVPRSGSWARPCREQGHPAVLAL 312
               P      PG   +R   G    +          PQ P   +   P  E+GHP     
Sbjct: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET--GPIGERGHPG---- 988

Query: 313  QSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRS-PGPEGTSDAARAPAPGLRD 371
              P PP            G   +PG   ++ +     LR  PG  G   A    APGL+ 
Sbjct: 989  -PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA--QGAPGLKG 1045

Query: 372  RDLRAAPPRP--RPSQRPVSG 390
             +    PP P   P +R  +G
Sbjct: 1046 GEGPQGPPGPVGSPGERGSAG 1066



 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 89/334 (26%), Positives = 111/334 (33%), Gaps = 63/334 (18%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG-------AGPLPLVSRLGHAGE 120
           GD G R ER      G Q     P   G+R   D   G       AGP  L+   G  G 
Sbjct: 610 GDKGHRGER------GPQGPPGPPGDDGMRGE-DGEIGPRGLPGEAGPRGLLGPRGTPGA 662

Query: 121 RGSPGAGDVN----PVSASSPPGRPDPLLLTTFVFPPGKTSAP----RPSPGGRRGRPLG 172
            G PG   V+    P     P G P          PPG+   P     P P G  G P  
Sbjct: 663 PGQPGMAGVDGPPGPKGNMGPQGEPG---------PPGQQGNPGPQGLPGPQGPIGPP-- 711

Query: 173 AARGTGLNPGLS--PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR------G 224
             +G    PGL+  P    P GH    +   +   G      P     +  PR      G
Sbjct: 712 GEKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG 769

Query: 225 SRRLRPDAGK-----FPEASGGKGQRAAGAE------RVLNNGRGPRSRLPGLAGGVEPP 273
            R L+   G+     FP   G  G +    E      R  +   GP+ R  G  G   P 
Sbjct: 770 VRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR-AGPTGDPGPS 828

Query: 274 GWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGA 333
           G + E+   G+    P +P       P    G P             AR  A + GP G 
Sbjct: 829 GQAGEKGKLGV----PGLPGYPGRQGPKGSTGFPGFPGANGEKG---ARGVAGKPGPRGQ 881

Query: 334 TEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
             P     +  +R P    PGP+GTS     P P
Sbjct: 882 RGPTGPRGSRGARGP-TGKPGPKGTSGGDGPPGP 914



 Score = 39.3 bits (90), Expect = 0.008
 Identities = 89/373 (23%), Positives = 117/373 (31%), Gaps = 76/373 (20%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-RGGLRSRTDPA 103
            SP   G+A  +   G       QG  G   E+ A    G Q    GP  R G++      
Sbjct: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ----GPAGRDGVQGPVGLP 1113

Query: 104  FGAGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS 162
              AGP       G  GE G PG  G       + PPG            PPG        
Sbjct: 1114 GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG------------PPGLQ------ 1155

Query: 163  PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQS--ARRTDTASRAGWATRRAPSRRRNFG 220
              G  G P G A G G  PG       PRG Q    ++ D  +R G+     P   +   
Sbjct: 1156 --GPVGAP-GIAGGDG-EPG-------PRGQQGMFGQKGDEGAR-GFPGPPGPIGLQGLP 1203

Query: 221  APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL-----------PGLAGG 269
             P G +    D G      G  G R        +  +GP   +           PG AG 
Sbjct: 1204 GPPGEKGENGDVGPMGPP-GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262

Query: 270  VEPPGWSRERAGAGLSRDSPQVPRSGSWARPCRE--------QGHPAVLALQSPAPPSLA 321
              PPG +      G   +  +    G+   P  +        +G+P  +       P   
Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322

Query: 322  RAAARRRGPGGAT----EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAA 377
               A + G GG      +PG               PGP G S  A  P P  +     AA
Sbjct: 1323 PGPAGQDGVGGDKGEDGDPG--------------QPGPPGPSGEAGPPGPPGKRGPPGAA 1368

Query: 378  PPRPRPSQRPVSG 390
                R  ++   G
Sbjct: 1369 GAEGRQGEKGAKG 1381


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 101/384 (26%), Positives = 126/384 (32%), Gaps = 75/384 (19%)

Query: 105 GAGPLPLVSRLGHAGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP---- 159
           G GP+ L+   G  G  G+PG  G   P      PG+  P        PPGK        
Sbjct: 89  GPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPG 148

Query: 160 RPSPGGRRG--RPLGAARGTGLNPGLSPRLQEPRGH-----------------QSARRTD 200
           +P   G RG   P G ARG    PGL P  +  RGH                 +     +
Sbjct: 149 KPGRPGERGVVGPQG-ARGFPGTPGL-PGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGE 206

Query: 201 TASRAGWATRRAPSRRRNFGA--PRGSRRLRPDAGK--------------FPEASGGKGQ 244
             +      R  P  R   GA  P G+R      G               FP A G KG+
Sbjct: 207 NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGE 266

Query: 245 RAAGAERVLNNGRGPRSR--LPGLAGGVEPP------GWSRERAGAGLS--RDSPQVPRS 294
             A          GPR    LPGL+G V PP      G +  +  AGL     +P +P  
Sbjct: 267 IGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGP 326

Query: 295 GSWARPCREQGHPAVLALQSPAPPSLARAAARRRG-PGGATEPGFVTLAFRSRLPLLRSP 353
                P    G      L     P+ ++  +  +G PG A   G    +           
Sbjct: 327 RGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE-----GKR 381

Query: 354 GPEGTSDAARAPAP----------GLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGP 403
           GP G + +A  P P          GL   D RA    P P  R  SG   V+      GP
Sbjct: 382 GPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGP-PGSRGASGPAGVR------GP 434

Query: 404 GSSACEVAVPTTAGRELLGSEPRN 427
              A     P   G   L   P N
Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGN 458



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 92/331 (27%), Positives = 106/331 (32%), Gaps = 64/331 (19%)

Query: 58  PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
           PG   A    G  G R E  AA   G       P   G      P   AGP     + G 
Sbjct: 678 PGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGA 737

Query: 118 AGERGSPG-------AGDVNPVSASSPP---GRPDPLLLTTFVFPPGKTSAPRPSPGGRR 167
            GERG+ G        G   PV A+ P    G P P        PPG T    P   GR 
Sbjct: 738 KGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGF--PGAAGRT 795

Query: 168 GRP-LGAARGTGLNPGLSPR--LQEPRGHQS----ARRTDTASRAGWATRRAPSRRRNFG 220
           G P      G    PG + +  L+ PRG Q               G+A  + PS      
Sbjct: 796 GPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTA 855

Query: 221 APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERA 280
            P             P   G +G   A     L   RG R  LPG+AG V  PG      
Sbjct: 856 GP-------------PGTPGPQGLLGAPGILGLPGSRGERG-LPGVAGAVGEPG------ 895

Query: 281 GAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVT 340
             G+             A P   +G P   A+ SP        A R   PG    PG   
Sbjct: 896 PLGI-------------AGPPGARGPPG--AVGSPGVNGAPGEAGRDGNPGNDGPPG--- 937

Query: 341 LAFRSRLPLLRS----PGPEGTSDAARAPAP 367
              R   P  +     PG  G   AA AP P
Sbjct: 938 ---RDGQPGHKGERGYPGNIGPVGAAGAPGP 965



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 100/398 (25%), Positives = 131/398 (32%), Gaps = 56/398 (14%)

Query: 58  PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
           PG        G+ G   +  A    G +     P   G R         GP   +   G 
Sbjct: 195 PGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGP 254

Query: 118 AGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARG 176
            G  G+PG  G++  V  + P G   P      V  PG  S P   PG      L  A+G
Sbjct: 255 PGFPGAPGPKGEIGAVGNAGPAGPAGP---RGEVGLPG-LSGPVGPPGNPGANGLTGAKG 310

Query: 177 TGLNPGL--SPRLQEPRGHQSARRTDTASRA-GWATRRAPSRRRNFGAPRGSRRLRPDAG 233
               PG+  +P L  PRG         A+ A G      P+  +     +G        G
Sbjct: 311 AAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQG 370

Query: 234 KFPEASGGKGQRAAGAERVLNNGRGP--------RSRLPGL---AGGVEPPGWSRERAGA 282
             P  SG +G+R    E       GP           LPG    AG + PPG       A
Sbjct: 371 P-PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPA 429

Query: 283 GLSRDSPQVPRSGSWA--------------RPCREQGH---PAVLALQSPAPPSLARAAA 325
           G+   +    R G                  P  ++G    P +     P  P+ AR   
Sbjct: 430 GVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP 489

Query: 326 RR---RGPGGAT-EPGFVTLAFRSRLPLLR-SPGPEGTSDAARAPAP-GLRDRDLRAAPP 379
                 GP G T +PG       + L   R +PGP+G + A   P P G++       PP
Sbjct: 490 GNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPP 549

Query: 380 RPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAG 417
            P   Q    GL          GP   A EV  P   G
Sbjct: 550 GPPGFQ----GL---------PGPSGPAGEVGKPGERG 574



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 119/442 (26%), Positives = 144/442 (32%), Gaps = 75/442 (16%)

Query: 46  PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
           P   GAA  +   G        G  G    +    S G Q         G R     A  
Sbjct: 330 PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS 389

Query: 106 AGPLPLVSRLGHAGERGSPGA-------------GDVNPVSASSP---PGRP-DPLLLTT 148
           AGP       G  G RG PGA             G   P     P    GRP +P L+  
Sbjct: 390 AGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP 449

Query: 149 FVFP-------PGKTSAPRPSPG--GRRGRPLG--AARGTGLNPGLSPRLQEPRGHQSAR 197
              P       P     P   PG  GR G P+G   ARG   N G  P  + P G     
Sbjct: 450 RGLPGSPGNIGPAGKEGPVGLPGIDGRPG-PIGPAGARGEPGNIGF-PGPKGPTGDPG-- 505

Query: 198 RTDTASRAGWA-TRRAPSRRRNFGA--PRGSRRLRPDAGK-----------FPEASGGKG 243
           +      AG A  R AP    N GA  P G + ++   G+            P  SG  G
Sbjct: 506 KNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAG 565

Query: 244 QRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCRE 303
           +     ER L+   G    LPG AG     G   E   AG +        SG    P   
Sbjct: 566 EVGKPGERGLHGEFG----LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGP-PGPDGN 620

Query: 304 QGHPAVLALQSPAPPSLARAAARRRG----PGGATEPGFVTL----------AFRSRLPL 349
           +G P V+     A PS        RG    PGG  E G   L            R     
Sbjct: 621 KGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGA 680

Query: 350 LRSPGPEG-TSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSAC 408
           + +PGP G T D   A A G        A PR  P +R   G      F   +GP  +A 
Sbjct: 681 VGAPGPAGATGDRGEAGAAG----PAGPAGPRGSPGERGEVGPAGPNGF---AGPAGAAG 733

Query: 409 EVAVPTTAGRELLGSEPRNGTL 430
           +       G +  G +  NG +
Sbjct: 734 QPGAKGERGAK--GPKGENGVV 753



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 68/271 (25%), Positives = 82/271 (30%), Gaps = 37/271 (13%)

Query: 126 AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSP 185
           AGD  P     PPG P          PPG    P P   G         +G GL PG   
Sbjct: 35  AGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG-PM 93

Query: 186 RLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQR 245
            L  PRG   A         G+              P G+R      GK  E  G  G+ 
Sbjct: 94  GLMGPRGPPGA--AGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGE-DGHPGKP 150

Query: 246 AAGAERVLNNGRGPRS-----RLPGLAG--GVEPPGWSRERAGAGLSRDSPQVPRSGSWA 298
               ER +   +G R       LPG  G  G       + + GA   +  P  P      
Sbjct: 151 GRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTP 210

Query: 299 RPCREQGHPAVLALQSPAPPSLARAAARRRGP-------GGATEPGFVTLAFRSRLPLLR 351
                +G P          P+ AR +    GP       G A  PGF             
Sbjct: 211 GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFP-----------G 259

Query: 352 SPGPEGTSDAARAPAPGLRDRDLRAAPPRPR 382
           +PGP+G   A     P        A P  PR
Sbjct: 260 APGPKGEIGAVGNAGP--------AGPAGPR 282



 Score = 34.7 bits (78), Expect = 0.19
 Identities = 48/173 (27%), Positives = 62/173 (35%), Gaps = 23/173 (13%)

Query: 45   SPHVTGA---AQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSAT--------LGPR- 92
            SP V GA   A R   PG      + G  G + ER    ++G   A         +GP  
Sbjct: 914  SPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAG 973

Query: 93   RGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTT 148
            + G R  T P+   GP   V   G +G +G  G     G+  P       G      L  
Sbjct: 974  KHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPG 1033

Query: 149  FVFPPGKTSAP-RPSPGGRRG-----RPLGAARGTGLNPGLSPR-LQEPRGHQ 194
                 G   AP    P G RG      P G    TG    + P  ++ P+GHQ
Sbjct: 1034 IAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQ 1086


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 56.6 bits (135), Expect = 5e-08
 Identities = 82/328 (25%), Positives = 103/328 (31%), Gaps = 48/328 (14%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
            G A     PG       +G+ G + E   + + G       P   G +    P    G  
Sbjct: 1288 GEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDP 1347

Query: 110  PLVSRLGHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS-PG 164
                  G AG+ G PG     G+     +  P G P P        PPGK   P P+ P 
Sbjct: 1348 GPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGP------SGPPGKRGPPGPAGPE 1401

Query: 165  GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
            GR+G   GA    G        L+ P G     +T      G   +  P   R    P G
Sbjct: 1402 GRQGEK-GAKGEAG--------LEGPPG-----KTGPIGPQGAPGKPGPDGLRGIPGPVG 1447

Query: 225  SRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRL--PGLAGGVEPPGWSRERAGA 282
             + L       P   G  G         L    GP+     PGL G + PPG   E+   
Sbjct: 1448 EQGLPGS----PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDR 1503

Query: 283  GLSRDSPQVPRSGSW--ARPCREQGHPAVLALQSPAPPSLARAAARRRGP-GGATEPGFV 339
            GL          G      P    G P    L  P  P  A+ ++   GP G A  PG  
Sbjct: 1504 GLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPG-- 1561

Query: 340  TLAFRSRLPLLRSPGPEGTSDAARAPAP 367
                         PGP G       P P
Sbjct: 1562 ------------PPGPPGPPGEVIQPLP 1577



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 71/276 (25%), Positives = 89/276 (32%), Gaps = 48/276 (17%)

Query: 45   SPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
            SP   G       PG    A Q G  G + +       G+   T  P   G   +  P  
Sbjct: 1337 SPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPG 1396

Query: 105  GAGPLPLVSRLGHAGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPS 162
             AGP       G  GE G  G  G   P+     PG+P P  L     P G+   P  P 
Sbjct: 1397 PAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG 1456

Query: 163  PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP 222
            P G  G P+G     GL     P+ +  +GH            G    +     R    P
Sbjct: 1457 PDGPPG-PMGPPGLPGLKGDSGPKGE--KGHPG-----LIGLIGPPGEQGEKGDRGLPGP 1508

Query: 223  RGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGA 282
            +GS             SG KG++            GP    PGL G   PPG    +  +
Sbjct: 1509 QGS-------------SGPKGEQGITGPSGPIGPPGP----PGLPG---PPGPKGAKGSS 1548

Query: 283  GLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPP 318
            G     P  P+         E GHP       P PP
Sbjct: 1549 G-----PTGPKG--------EAGHPG-----PPGPP 1566



 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 92/352 (26%), Positives = 104/352 (29%), Gaps = 63/352 (17%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPR-RGGLRSRTDPAF 104
            P   G      TPG+     Q+G  G R ER      G      GP+   G      P  
Sbjct: 891  PGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKP----GPKGNSGGDGPAGPPG 946

Query: 105  GAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRP--- 161
              GP       G  G +G PG     P      PG P     T F    GKT  P P   
Sbjct: 947  ERGPNGPQGPTGFPGPKGPPG-----PPGKDGLPGHPGQRGETGF---QGKTGPPGPPGV 998

Query: 162  ----SPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRR 217
                 P G  G P+G  RG    PG       P G Q       A + G      P+   
Sbjct: 999  VGPQGPTGETG-PMG-ERGHPGPPG-------PPGEQGL--PGLAGKEGTKGDPGPAGLP 1047

Query: 218  NFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSR 277
                P G R    D G  P   G  G         L    GP    PG  G    PG  R
Sbjct: 1048 GKDGPPGLRGFPGDRG-LPGPVGALG---------LKGNEGP----PGPPGPAGSPG-ER 1092

Query: 278  ERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPG 337
              AGA      P  P       P  E+G P     Q PA     +      GP G   P 
Sbjct: 1093 GPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP- 1151

Query: 338  FVTLAFRSRLPLLRSPGPEGTSDAARAPA-PGLRDRDLRAAPPRPRPSQRPV 388
                           PG +G       P   G +       PP P   Q P+
Sbjct: 1152 ---------------PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPI 1188



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 92/359 (25%), Positives = 117/359 (32%), Gaps = 75/359 (20%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G   +   PG  R  P  GD G      A    G +     P   G      PA  
Sbjct: 1041 PGPAGLPGKDGPPG-LRGFP--GDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGA 1097

Query: 106  AGPLPLVSR------LGHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPG- 154
            AGP+ +  R       G AGE+G+PG     G         P G P P      V PPG 
Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP---AGPVGPPGE 1154

Query: 155  ------------------KTSAPRPSPGGRRGRPLGAARGTGLN--PGLSPRLQEPRGHQ 194
                              K     P P G +G P+G    +G +  PG       PRG Q
Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQG-PIGQPGPSGADGEPG-------PRGQQ 1206

Query: 195  S--ARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKF--PEASGGKGQRAA-GA 249
                ++ D   R G+     P   +    P G +    D G+   P   G +G   A GA
Sbjct: 1207 GLFGQKGDEGPR-GFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGA 1265

Query: 250  ERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAV 309
            +       GP+    G  GG+  PG   E+   G     P +P  G    P  E+G    
Sbjct: 1266 D-------GPQ----GPPGGIGNPGAVGEKGEPG-EAGEPGLPGEGGPPGPKGERGEKGE 1313

Query: 310  LALQSPAPPSLARAAARRRGPGGATEP-GFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
                  A P   +      GP G+  P GF              PGP G    A    P
Sbjct: 1314 SGPSGAAGPPGPKGPPGDDGPKGSPGPVGFP-----------GDPGPPGEPGPAGQDGP 1361



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 84/327 (25%), Positives = 104/327 (31%), Gaps = 75/327 (22%)

Query: 67  QGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA 126
           +G+ G + E A  E         GP   G      P    GP     ++G  GERG PG 
Sbjct: 449 RGEKGQKGEPAIIEPGMLIEGPPGPE--GPAGLPGPPGTMGP---TGQVGDPGERGPPGR 503

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPR-------------------------P 161
             +    A   PG P  +L+  F F  G  +  +                          
Sbjct: 504 PGL--PGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPA 561

Query: 162 SPGGRRGR--PLGAARGTGL--NPG-LSPRLQEPRGHQSARRTDTASRAGWATRRAPSRR 216
            P G  GR  P+G     GL   PG + P  Q PRG Q          AG      P RR
Sbjct: 562 GPMGLTGRPGPVGPPGSGGLKGEPGDVGP--QGPRGVQG-----PPGPAG-----KPGRR 609

Query: 217 RNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWS 276
              G+  G+R +       P  +G KG R       L   +G R   PG +G   PPG  
Sbjct: 610 GRAGSD-GARGM-------PGQTGPKGDRGFDGLAGLPGEKGHRGD-PGPSGPPGPPGDD 660

Query: 277 RERAGAGL--SRDSPQVPRSGSWARPCREQGHPAVLALQ----SPAPPSLARAAARRRGP 330
            ER   G    R  P  P       P    G P    +      P P            P
Sbjct: 661 GERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPP 720

Query: 331 GGATEPGFVTLAFRSRLPLLRSPGPEG 357
           G    PG   L           PGP+G
Sbjct: 721 GQQGNPGAQGL-----------PGPQG 736


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 89/375 (23%), Positives = 122/375 (32%), Gaps = 47/375 (12%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
           G   +   PG        G  G  R  +A  +   + + LG + G +     P    GP 
Sbjct: 165 GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224

Query: 110 PLVSRLGHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP----RP 161
            L  + G AG  G PG     G + P+ +  P G P           PG+   P     P
Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG---------KPGEDGEPGRNGNP 275

Query: 162 SPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSAR-RTDTASRAGWATRRAPSRRRNFG 220
              G  G P   ARG    PGL P L+  RGH+            G      P+      
Sbjct: 276 GEVGFAGSP--GARGFPGAPGL-PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAM 332

Query: 221 APRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERA 280
            P G R +  + G+     G  GQR A          GP   +PG +G    PG   E  
Sbjct: 333 GPLGPRGMPGERGRL-GPQGAPGQRGAHGMPGKPGPMGPLG-IPGSSGFPGNPGMKGEAG 390

Query: 281 GAGL-SRDSPQVPRSGSW-ARPCREQGHPAVLALQ-SPAPPSLARAAARRRGPGGATEPG 337
             G    + PQ  R  +    P    G P  +    +P       +      PG A  PG
Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 338 FVTLAFRSRLPLLRSPGPEGTS-------DAARAPAPGLRDRDLRAAPPRPRPSQRPVSG 390
                         SPGP+G++              PG +        P P   Q P+  
Sbjct: 451 --------------SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP 496

Query: 391 LFKVKFFVPQSGPGS 405
             +     P+  PG+
Sbjct: 497 PGEEGKRGPRGDPGT 511



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 90/330 (27%), Positives = 109/330 (33%), Gaps = 52/330 (15%)

Query: 58  PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRS-RTDPAFGAGPLPLVSRLG 116
           PG       +G+ G + E       G Q     P   G R  R DP     P P+  R G
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPH---GIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGER-G 522

Query: 117 HAGERGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPG--GRRGRP-LG 172
             G RG PG+ G   P  A    G             P  +S P+ S G  GR G P L 
Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERG-------------PVGSSGPKGSQGDPGRPGEPGLP 569

Query: 173 AARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDA 232
            ARG   NPG    +Q P G     +       G   R  P          GS  L    
Sbjct: 570 GARGLTGNPG----VQGPEG-----KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPK 620

Query: 233 GKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG-------LS 285
           G       GK   A  A      G   +    G +G V PPG + ER   G         
Sbjct: 621 GS--SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG 678

Query: 286 RDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRS 345
              P  P  G   +P  +QG P       P  P        R  PG   EPG   L    
Sbjct: 679 LPGPPGP-PGEGGKP-GDQGVPGDPGAVGPLGP-----RGERGNPGERGEPGITGLPGEK 731

Query: 346 RLPLLRSP-GPEGTSDAARAPA----PGLR 370
            +     P GP+G+   +  P     PGL+
Sbjct: 732 GMAGGHGPDGPKGSPGPSGTPGDTGPPGLQ 761



 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 101/401 (25%), Positives = 122/401 (30%), Gaps = 97/401 (24%)

Query: 55   SPTP-GRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVS 113
            SP P G A +    G  G    +    + G   AT  P   G      PA   GP     
Sbjct: 874  SPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP---AG 930

Query: 114  RLGHAGERGSPGA-------GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS---- 162
             LG  G+ G PG        G V     + PPG P           PG    P P+    
Sbjct: 931  PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG 990

Query: 163  -------PG--GRRGRP-----------LGAARGTGLN--------PGLSPRLQEPRGHQ 194
                   PG  G RG P           +G    TG          PG +  + EP    
Sbjct: 991  QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG 1050

Query: 195  SARRTDTASRAGWATRR----------------APSRRRNFGAPRGSRRLRPDAGK---- 234
             A    T  R G    R                AP      GAP G    R D G     
Sbjct: 1051 PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP-GDAGQRGDPGSRGPI 1109

Query: 235  ----------FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGL 284
                       P   G +G +    +R     +G R    GL G   PPG + E+  AG+
Sbjct: 1110 GPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRG-FTGLQGLPGPPGPNGEQGSAGI 1168

Query: 285  SRDSPQVPRSGSW-ARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGAT-EPGFVTLA 342
                P  PR       P  ++G+P  L    P  P   R +    GP G   EPG     
Sbjct: 1169 --PGPFGPRGPPGPVGPSGKEGNPGPL---GPIGPPGVRGSVGEAGPEGPPGEPG----- 1218

Query: 343  FRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRP 383
                      PGP G   AA     G  D  +    P P P
Sbjct: 1219 ------PPGPPGPPGHLTAALGDIMGHYDESM----PDPLP 1249



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 80/306 (26%), Positives = 105/306 (34%), Gaps = 57/306 (18%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA- 126
           G  G   ER A  + G   +   P   G +    P   +GP       G  GE G PGA 
Sbjct: 513 GPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPG--GRRGRP----LGAARGTGLN 180
           G         P G+  PL        PG+   P P PG  G RG+P    L   +G+  +
Sbjct: 573 GLTGNPGVQGPEGKLGPL------GAPGEDGRPGP-PGSIGIRGQPGSMGLPGPKGSSGD 625

Query: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240
           PG               +   A  AG      P +R   GAP     + P        SG
Sbjct: 626 PG---------------KPGEAGNAG-----VPGQR---GAPGKDGEVGP--------SG 654

Query: 241 GKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRD----SPQVPRSGS 296
             G      ER      GP +   GL G   PPG   +    G+  D     P  PR G 
Sbjct: 655 PVGPPGLAGERGEQGPPGP-TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR-GE 712

Query: 297 WARPCREQGHPAVLALQSPAPPSLARAAARRRG-PGGATEPGFVTLAFRSRLP----LLR 351
              P  E+G P +  L      +        +G PG +  PG         +P    +  
Sbjct: 713 RGNP-GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771

Query: 352 SPGPEG 357
           +PGP+G
Sbjct: 772 TPGPKG 777



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 93/385 (24%), Positives = 116/385 (30%), Gaps = 41/385 (10%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGG------LRSRTDPAFGAGPLPLVSRLGHAGER 121
           G  GA+ ER    S G + +   P R G       R  T      GP   +  LG  GE 
Sbjct: 537 GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGED 596

Query: 122 GSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLN 180
           G PG  G +         G P P   +     PG+  A      G+RG P          
Sbjct: 597 GRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGE--AGNAGVPGQRGAPGKDGEVGPSG 654

Query: 181 PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASG 240
           P   P L   RG Q           G+     P      G   G + +  D G      G
Sbjct: 655 PVGPPGLAGERGEQG-----PPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL-G 708

Query: 241 GKGQRAAGAERVLNNGRGPRSRLP---GLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSW 297
            +G+R    ER    G    + LP   G+AGG  P G       +G   D+         
Sbjct: 709 PRGERGNPGER----GEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT--------- 755

Query: 298 ARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEG 357
             P   QG P    +     P   R     +G  G           R     L  PGP G
Sbjct: 756 -GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND----GARGLPGPLGPPGPAG 810

Query: 358 TSDAARAPAPGLRDRDLRAAP-PRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTA 416
            +     P P    R L   P  R  P  R  +G      F    GP         P   
Sbjct: 811 PTGEKGEPGP----RGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEP 866

Query: 417 GRELLGSEPRNGTLESICSLHVGNG 441
           G++     P    L      H  NG
Sbjct: 867 GQKGDAGSPGPQGLAGSPGPHGPNG 891



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 51/154 (33%), Positives = 60/154 (38%), Gaps = 25/154 (16%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSA--TLGP--RRGGLRSRTD 101
            P   G A    TPGR  A  ++GD G   +   A   G+Q A  T GP    G    R D
Sbjct: 1046 PGPEGPAGNDGTPGRDGAVGERGDRG---DPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD 1102

Query: 102  PAFGAGPLPLVSRLGHAGERGSPG-------AGDVNPVSASSPPGRPDPLLLTTFVFPPG 154
            P    GP   +   G AG+RG PG        GD          G      L     PPG
Sbjct: 1103 PG-SRGP---IGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPG 1158

Query: 155  ----KTSAPRPSPGGRRG--RPLGAARGTGLNPG 182
                + SA  P P G RG   P+G +   G NPG
Sbjct: 1159 PNGEQGSAGIPGPFGPRGPPGPVGPSGKEG-NPG 1191



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 87/328 (26%), Positives = 106/328 (32%), Gaps = 42/328 (12%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG A    ++G+ G R        +G   +   P   G    T     AGP     + G 
Sbjct: 806  PGPAGPTGEKGEPGPRG------LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859

Query: 118  AGERGSPG----AGDVNPVSASSPPGRPDPLLLTTF------VFPPGKTSAPRPSPGGRR 167
             GE G PG    AG   P   +  PG   P  +           PPG T    P   GR 
Sbjct: 860  KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGF--PGSAGRV 917

Query: 168  GRPLGAARGTGLNPGLSPRLQEP-RGHQSARRTDTASRAGWATR---RAPSRRRNFGAPR 223
            G P     G    PG +  L EP +      R D  S      R     P    + G P 
Sbjct: 918  GPP-----GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972

Query: 224  GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
               +  PD    P  +G  GQR       +   RG R  +PGL G    PG        G
Sbjct: 973  EDGQPGPDGP--PGPAGTTGQRGIVG---MPGQRGERG-MPGLPGPAGTPGKVGPTGATG 1026

Query: 284  LSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAF 343
                   V   GS   P  E G        +   P    A   R   G   +PG   L  
Sbjct: 1027 DKGPPGPVGPPGS-NGPVGEPGPEGPAG--NDGTPGRDGAVGER---GDRGDPGPAGLPG 1080

Query: 344  RSRLPLLRSPGPEGT-SDAARAPAPGLR 370
                P   +PGP G   DA +   PG R
Sbjct: 1081 SQGAP--GTPGPVGAPGDAGQRGDPGSR 1106


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 96/358 (26%), Positives = 114/358 (31%), Gaps = 53/358 (14%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG    A  +G  G +  R     +G       P   GL     PA   GP  L    G 
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG---PAGPQGPSGLK---GE 2208

Query: 118  AGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-------RPSPGGRRGRP 170
             GE G PG G   P  A   PG P P   +  V P G    P       +P   GR G  
Sbjct: 2209 PGETGPPGRGLTGPTGAVGLPGPPGP---SGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265

Query: 171  -LGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP------- 222
                 RG+   PG SP L  P G +           G A    P  +   GAP       
Sbjct: 2266 GKDGDRGSPGVPG-SPGLPGPVGPKG--EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322

Query: 223  ------RGSRRLRPDAGKFPEAS--------GGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
                  +G R L    G+  EA         G  GQ+ A   +       P   +PG  G
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG--DPGVGVPGSPG 2380

Query: 269  GVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRR 328
               PPG   +    GL   +P V        P  E G P     +  A P          
Sbjct: 2381 PPGPPGVKGDLGLPGLP-GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439

Query: 329  G----PGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPR 382
            G    PG    PG   L      P +  PGP G         PG+R  D R     PR
Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG-----ERGEPGIRGEDGRPGQEGPR 2492



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 96/364 (26%), Positives = 115/364 (31%), Gaps = 71/364 (19%)

Query: 50   GAAQRSPTPGRA-----------RAAP----QQGDGGARRERAAAESLGTQSATLGPRRG 94
            GA  R  +PGRA           + +P     +GD G R  R      G     +G    
Sbjct: 1302 GADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP 1361

Query: 95   GLRSRTDPAFGAGPLPLVSRLGHAGERGSPG------AGDVNPVSASSPPGRPDPLLLTT 148
            GL  R      +GP      LG  G RG PG       GD        PPG  +  +   
Sbjct: 1362 GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPG 1421

Query: 149  FVFPPGKTSAPRPS-----PG--GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDT 201
                PG   +P P      PG  G +G     A G    PG SP  Q PRG   A     
Sbjct: 1422 EPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPG-SPGEQGPRGPPGA----- 1475

Query: 202  ASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRS 261
                       P   R F  P G    + + G  P  +G +G              GP  
Sbjct: 1476 ---------IGPKGDRGFPGPLGEAGEKGERGP-PGPAGSRGLPGVAGRPGAKGPEGP-- 1523

Query: 262  RLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLA 321
              PG      P G   E+   G   D   V    + A P  E+G         PA P  A
Sbjct: 1524 --PG------PTGRQGEKGEPGRPGDPAVV--GPAVAGPKGEKGD------VGPAGPRGA 1567

Query: 322  RAAARRRGPGGATEPGFV----TLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAA 377
                  RGP G   PG          R  + L    GP G S       PG +    R  
Sbjct: 1568 TGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSG-----PPGEKGDPGRPG 1622

Query: 378  PPRP 381
            PP P
Sbjct: 1623 PPGP 1626



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 98/368 (26%), Positives = 119/368 (32%), Gaps = 78/368 (21%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG        G  G + E+      G   A +GP   G +        AGP       G 
Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPG-DPAVVGPAVAGPKGEKGDVGPAGPR---GATGV 1570

Query: 118  AGERGSPG---AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP----------RPSPG 164
             GERG PG    GD  P      PG   P+ LT    PPG +  P           P P 
Sbjct: 1571 QGERGPPGLVLPGDPGP---KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV 1627

Query: 165  GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRG 224
            G RGR           P   P L    G +               R AP  R     P G
Sbjct: 1628 GPRGRDGEVGEKGDEGPPGDPGLPGKAGER-------------GLRGAPGVR----GPVG 1670

Query: 225  SRRLRPDAGK-----FPEASGGKGQRAAGAE-----RVLNNGRGPRSR-LPGLAGGVEP- 272
             +  + D G+      P +SG KG R          R+++ G G R +  PG  G   P 
Sbjct: 1671 EKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPR 1730

Query: 273  --------PGWSRERAGAGLSRDSPQVPRSGSWAR-PCREQGHPAVLALQSPAPPSLARA 323
                    PG   ER   G     P  P+     R P  E+G      L   +       
Sbjct: 1731 GPKGDPGLPGAPGERGIEGFR--GPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPG 1788

Query: 324  AARRRGPGGAT----EPGFVTLAFRSRLPLLRS----PGPEGTSDAARAPA----PGLRD 371
            AA   GP GA     +PG      R  LP LR     PGP G       P     PGL  
Sbjct: 1789 AAGPSGPNGAAGKAGDPG------RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 372  RDLRAAPP 379
            ++     P
Sbjct: 1843 KNGEPGDP 1850



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 76/257 (29%), Positives = 93/257 (36%), Gaps = 51/257 (19%)

Query: 114  RLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFP--PGKTS--APRPSPGGRRGR 169
            R G  GERG+PG      +    PPG P P+      FP  PG T     R   G +  +
Sbjct: 1870 RDGPKGERGAPGI-----LGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 170  PLGAARGTGLNPGLSP---RLQEPRGHQ-SARR--TDTASRAGWATRRAPSRRRNFGAPR 223
             L   RG    PG  P   RL E  G + SA R   +T   +  +    P RRR    P+
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRG---PK 1981

Query: 224  GSRRLRPDAGK-----FPEASGGKGQRA----AGAERVLNNGRGPRSR------------ 262
            G    +   GK     FP   G KG R      G   +    RGP               
Sbjct: 1982 GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI 2041

Query: 263  --LPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSL 320
              LPG AGGV   G   ER   G   +  +  R G    P    G P       P PP  
Sbjct: 2042 PGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP----GTPG-----PPGPPG- 2091

Query: 321  ARAAARRRGPGGATEPG 337
             + +    GPG + E G
Sbjct: 2092 PKVSVDEPGPGLSGEQG 2108



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 102/374 (27%), Positives = 125/374 (33%), Gaps = 54/374 (14%)

Query: 56   PTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRL 115
            P PG +      G  GA+ E  +    G +     P   G R    P    G   L    
Sbjct: 2099 PGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGER 2158

Query: 116  GHAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFP---------PGKTSAP--- 159
            G AG  G PG     G   PV     PG P    L     P         PG+T  P   
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRG 2218

Query: 160  RPSPGGRRGRPLGAARGTGL-----NPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPS 214
               P G  G P G    +GL     +PGL  ++ E  G   A   D AS      R +P 
Sbjct: 2219 LTGPTGAVGLP-GPPGPSGLVGPQGSPGLPGQVGE-TGKPGAPGRDGASGKD-GDRGSP- 2274

Query: 215  RRRNFGAPRGSRRLRPDAGK--FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGG-VE 271
                 G P GS  L    G    P  +G  GQ   G    L   +G +    GLAG  V 
Sbjct: 2275 -----GVP-GSPGLPGPVGPKGEPGPTGAPGQAVVG----LPGAKGEKGAPGGLAGDLVG 2324

Query: 272  PPGWSRERAGAGLSRDSPQVPRSGSWARPCRE-----------QGHPAVLALQSPAPPSL 320
             PG   +R   G   +  +  R+G    P  +           +G P V    SP PP  
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384

Query: 321  ARAAARRRGPGGATEPGFVTLAFRS-RLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPP 379
                     PG    PG V    ++     +  PGP G  +   A  PG         PP
Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSG--ERGLAGPPGREGIPGPLGPP 2442

Query: 380  RPRPSQRP--VSGL 391
             P  S  P   SGL
Sbjct: 2443 GPPGSVGPPGASGL 2456



 Score = 36.2 bits (82), Expect = 0.064
 Identities = 88/356 (24%), Positives = 111/356 (31%), Gaps = 48/356 (13%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P V G       PG        G  G R E       G +     P R G+     P   
Sbjct: 2385 PGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGP 2444

Query: 106  AGPLPLVSRLGHAGERGSPGAGDVNPVSASSPP------GRPDPLLLTTFVFPPGKT--- 156
             G +      G  G++G PG G   P      P      GRP          PPG     
Sbjct: 2445 PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGER 2504

Query: 157  -------SAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSAR--RTDTASRAGW 207
                   SA      G     LG     G    +  R   PRG    +  R D       
Sbjct: 2505 GEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGER--GPRGLDGDKGPRGDNGDPGDK 2562

Query: 208  ATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLA 267
             ++  P  + + G P G R L    G+ P A+G  G   +  +  +   RG +    G  
Sbjct: 2563 GSKGEPGDKGSAGLP-GLRGLLGPQGQ-PGAAGIPGDPGSPGKDGVPGIRGEK----GDV 2616

Query: 268  GGVEPPGWSRER---AGAGLSRDSPQVPRSGSWARP-----CREQGHPAVLALQSPAP-- 317
            G + P G   ER      GL  +      +G   RP       E G P V   QS AP  
Sbjct: 2617 GFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPG-QSGAPGK 2675

Query: 318  -----PSLARAAARRRGP-GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP 367
                 P   R    + GP G   E G      R    +   PGP G   +A  P P
Sbjct: 2676 EGLIGPKGDRGFDGQPGPKGDQGEKG-----ERGTPGIGGFPGPSGNDGSAGPPGP 2726



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 76/308 (24%), Positives = 96/308 (31%), Gaps = 65/308 (21%)

Query: 80   ESLGTQSATLGPRRG--GLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSP 137
            ES G+       RRG  G      P    GP+      G  G+RG PG           P
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPG--------PQGP 2016

Query: 138  PGRPDPLLLTTFVFPPGKTS-APRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSA 196
            PG     L      PPG +  A  P   G  G P    R  G+     P  +  RG +  
Sbjct: 2017 PG-----LALGERGPPGPSGLAGEPGKPGIPGLP---GRAGGVGEAGRPGERGERGEKGE 2068

Query: 197  RRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNG 256
            R        G   R  P        P G     P   K      G G         L+  
Sbjct: 2069 R--------GEQGRDGPPGLPGTPGPPG-----PPGPKVSVDEPGPG---------LSGE 2106

Query: 257  RGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPA 316
            +GP    PGL G    PG + ++   G  R  P +        P  + G+P +   +  A
Sbjct: 2107 QGP----PGLKGAKGEPGSNGDQGPKG-DRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA 2161

Query: 317  PPSLARAAARRRGP----GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAP-GLRD 371
             P         RGP    GG  +PG               PG  G +  A    P GL+ 
Sbjct: 2162 GPEGKPGLQGPRGPPGPVGGHGDPG--------------PPGAPGLAGPAGPQGPSGLKG 2207

Query: 372  RDLRAAPP 379
                  PP
Sbjct: 2208 EPGETGPP 2215


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 94/343 (27%), Positives = 113/343 (32%), Gaps = 61/343 (17%)

Query: 46  PHVTGAA-QRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAF 104
           P V G+  Q+    G   A   +G  GA     A   +G +     P   GLR +     
Sbjct: 643 PGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG 702

Query: 105 GAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP----- 159
             G   L+   G  G  G PG     P      PG P  +       PPG T  P     
Sbjct: 703 PPGIPGLLGLQGPPGPPGVPG-----PPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGP 757

Query: 160 --RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRR 217
              P P G +G P    RG    PG  P L+   G Q           G A R  P  + 
Sbjct: 758 NGPPGPPGTKGEP--GERGEDGLPG-KPGLRGEIGEQ-----------GLAGR--PGEKG 801

Query: 218 NFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSR 277
             G         P A  FP   G KG +    E  L   +G R    G AG   PPG   
Sbjct: 802 EAGL--------PGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE-KGEAGPAGPPGLP- 851

Query: 278 ERAGAGLSRDSPQVP-------RSGSWARPCRE--QGHPAVLALQSPAPPSLARAAARRR 328
                 L    P++P         G    P     QG P  L  Q P  P  A+      
Sbjct: 852 --GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAH 909

Query: 329 G-PGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLR 370
           G PG A  PG            + +PGP G   +    APGLR
Sbjct: 910 GAPGAAGNPG--------APGHVGAPGPSGPPGS--VGAPGLR 942



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 90/345 (26%), Positives = 111/345 (32%), Gaps = 78/345 (22%)

Query: 50   GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGA--- 106
            GA      PG+ +     G+ G R        LGT++A      G +R   + A G    
Sbjct: 973  GAPGLPGPPGKGK----DGEPGLRGSPGLPGPLGTKAAC-----GKVRGSENCALGGQCV 1023

Query: 107  -GPLPLVSRLGHAGERGSPGAGDVNPVSASSPP---GRPDPLLLTTFVFPPGKTSAPRPS 162
             G        G  G RG PG G   P   S PP   G P    L  F  P G        
Sbjct: 1024 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG-------- 1075

Query: 163  PGGRRGRPLG-AARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGA 221
            P GR G P     RG    PGLS  L    G  +    D  +                  
Sbjct: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSP--GDINLLAKDVCN----------------DC 1117

Query: 222  PRGSRRLRPDAGKFPEASGGKGQRAAGAE--RVLNNGRGPRSRLPGLAGGVEPPGWSRER 279
            P G   L       P   G KG +    +  R    G+   +  PGL G   PPG +  +
Sbjct: 1118 PPGPPGL-------PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG---PPGIAGPQ 1167

Query: 280  AGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQ----SPAPPSLARAAARRRGPGGATE 335
               G      +V + G       +QGHP V        +P PP     A     PG    
Sbjct: 1168 GSQGERGADGEVGQKG-------DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 336  PGFVTLAFRSRLPLLRSPGPEGTSDAARAPA-PGLRDRDLRAAPP 379
            PG               PGP+G S     P   G   RD +  PP
Sbjct: 1221 PG-----------KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 1254



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 68/284 (23%), Positives = 97/284 (34%), Gaps = 53/284 (18%)

Query: 56   PTPGRARAAP----QQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPL 111
            P P  AR  P      GD GA   R  + ++G       P + G    T P    GP   
Sbjct: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR-- 1323

Query: 112  VSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPL 171
                G  G+ GSPG+           PG P                 P  +PG +     
Sbjct: 1324 ----GPPGKNGSPGS-----------PGEP----------------GPSGTPGQK----- 1347

Query: 172  GAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSR--RRNFGAPRGSRRLR 229
              ++G   +PGL P    PRG       +   +        P +     F   RG   ++
Sbjct: 1348 -GSKGENGSPGL-PGFLGPRGPPG----EPGEKGVPGKEGVPGKPGEPGFKGERGDPGIK 1401

Query: 230  PDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSP 289
             D G  P   G  G       +      GP+  LPG  G V PPG   +    GL  +SP
Sbjct: 1402 GDKGP-PGGKGQPGDPGIPGHKGHTGLMGPQG-LPGENGPVGPPGPPGQPGFPGLRGESP 1459

Query: 290  QVPRSGSWAR-PCREQGHPAVLALQSPAPPSLARAAARRRGPGG 332
             +       +    +Q    +  L +  PP+  +++  R GP G
Sbjct: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG 1503



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 86/336 (25%), Positives = 106/336 (31%), Gaps = 66/336 (19%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P + G       PG        G  GA+ +  A  + G       P   G    + P   
Sbjct: 876  PGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS 935

Query: 106  AGPLPLVSRLGHAGERGSPGA----GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRP 161
             G   L    G  GERG  GA    G   PV     PG P          PPGK      
Sbjct: 936  VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG------LPGPPGK------ 983

Query: 162  SPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGA 221
               G+ G P     G   +PGL   L         R ++  +  G         + + GA
Sbjct: 984  ---GKDGEP-----GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV------KGDRGA 1029

Query: 222  PRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAG 281
            P             P + G +G    G         GP    PG +G   PPG       
Sbjct: 1030 P-----------GIPGSPGSRGDPGIGV-------AGP----PGPSG---PPGDKGSPGS 1064

Query: 282  AGL-SRDSPQVP--RSGSWARPCREQGHPAVLALQSPAPPS----LARAAARRRGPGGAT 334
             GL     PQ P  R G+   P  E+G P    L S   P     LA+       PG   
Sbjct: 1065 RGLPGFPGPQGPAGRDGAPGNP-GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG 1123

Query: 335  EPGFVTLAFRSRLPLLRSPGPEGT-SDAARAPAPGL 369
             PG     F+    +   PG EGT      A  PGL
Sbjct: 1124 LPGLP--GFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157



 Score = 33.5 bits (75), Expect = 0.42
 Identities = 93/372 (25%), Positives = 119/372 (31%), Gaps = 52/372 (13%)

Query: 68  GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA- 126
           G  G++  R     LG       P   G+R    P    GP   V   G  GERG  G  
Sbjct: 542 GRDGSKGMRGEPGELGEPGL---PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTR 598

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRP-------SPGGRRGRPLGAARGTGL 179
           G+         PG+P     T     PG +    P        P G  G P    +  GL
Sbjct: 599 GEKGERGLDGFPGKPGD---TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL 655

Query: 180 N-----PGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGK 234
                 PG       PRGHQ A         G    R P        P G + LR   G 
Sbjct: 656 KGEQGAPG-------PRGHQGA--------PGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700

Query: 235 F--PEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG-LSRDSPQV 291
              P   G  G +       +    GP    PGL G +  PG        G   +D P  
Sbjct: 701 MGPPGIPGLLGLQGPPGPPGVPGPPGPGGS-PGLPGEIGFPGKPGPPGPTGPPGKDGPNG 759

Query: 292 PRS--GSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPL 349
           P    G+   P  E+G   +     P  P L      +   G   E G   L      P 
Sbjct: 760 PPGPPGTKGEP-GERGEDGL-----PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPG 813

Query: 350 LR-SPGPEGTSDAARAPAPGLR-DRDLRA-APPRPRPSQRPVSGLFKVKFFVP-QSGPGS 405
           +R   G +G  +      PGL+ DR  +  A P   P     + LF     +P + GP  
Sbjct: 814 VRGEKGDQG--EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871

Query: 406 SACEVAVPTTAG 417
              +  +P   G
Sbjct: 872 EKGDPGLPGEPG 883


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 53.5 bits (127), Expect = 4e-07
 Identities = 94/367 (25%), Positives = 124/367 (33%), Gaps = 52/367 (14%)

Query: 39  AEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRS 98
           A A   +P        +P P  +   P      A R   AA ++G +   L  R GG+  
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP--LAERAGGIGG 67

Query: 99  RTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPD--PLLLTTFVFP---P 153
            T P               AG   S G    NP S     GR +  P    T   P   P
Sbjct: 68  ATIPESAP----------RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 154 GKTSAP-RPSPGGRRGRPLGA----ARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWA 208
           G+ S   RP P G++G  + A    ARG          L        ARR  +    G  
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA-----GARRDTSGPTPGTP 172

Query: 209 TRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
           +     R R  G   G  R  P A   P   G +   ++ +E           R P   G
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 269 GVEPPGWSRERAGAGLSRDSPQVPRSGSWARPC-REQGHPA---VLALQSPAPPSLA--- 321
           G++ P  SR  + +     SP   RSG  AR   R   HP+      LQ+  PP +    
Sbjct: 233 GLQRPA-SRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 322 RAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRP 381
           + AA   GP  ++               L +P P GT  A   P P      L A  P  
Sbjct: 290 KDAAPALGPLSSSP--------------LATPSPSGTK-ARPVPPPDNAATPLPATLPPS 334

Query: 382 RPSQRPV 388
            P   P+
Sbjct: 335 PPLATPL 341



 Score = 36.6 bits (83), Expect = 0.049
 Identities = 97/394 (24%), Positives = 136/394 (34%), Gaps = 52/394 (13%)

Query: 25  GDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARR---------- 74
           G  +R A  SL  SA  L  SP  +G + R  TP RA A P Q      +          
Sbjct: 232 GGLQRPASRSLSSSATPLS-SPARSGPSARG-TP-RAPAHPSQPKPKGLQALRPPQVTPP 288

Query: 75  ERAAAESLGTQSAT--LGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPV 132
            + AA +LG  S++    P   G ++R  P       PL + L  +    +P    + P 
Sbjct: 289 RKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP--LAPP 346

Query: 133 SASSPPGR---PDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQE 189
           S S+PP     P P        PP  T+ P  +P   +  P         +   SP LQ 
Sbjct: 347 SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP----HSLTSPSLQA 402

Query: 190 PRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL----RPDAGKFPEASGGKGQR 245
           P    +       +  G  T +A          +    L    RP A   P++   +   
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP-ASTPPDSPPLQAPL 461

Query: 246 AAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQG 305
           +  A   L       S  P ++    P      +A + L+  SPQ P S     P   Q 
Sbjct: 462 SLPASPPLQT-----SLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQS 516

Query: 306 HPAVLALQSP---------------APPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
             A  +LQ+P               APP L  A+A    P   T P       ++    L
Sbjct: 517 SLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL 576

Query: 351 RSPGPEGTSDAARAP---APGLRDRDLRAAPPRP 381
            +P PE  S  A  P    P L    L+  P  P
Sbjct: 577 TTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610



 Score = 30.0 bits (66), Expect = 4.6
 Identities = 73/280 (26%), Positives = 91/280 (32%), Gaps = 78/280 (27%)

Query: 98  SRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTS 157
           S+  P+  A PL +           SP A      SA+ PP  P PL       PP   +
Sbjct: 693 SQAPPSLAAPPLQVPP---------SPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 158 APRPSPGGR---RGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPS 214
           +P  SP      R  PL AA          P LQ P                      PS
Sbjct: 744 SPPMSPSATPPPRVPPLLAA----------PPLQVP----------------------PS 771

Query: 215 RRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPG 274
                  P  S  + P A   P+A        A A   L     P +  PG A    P  
Sbjct: 772 -------PPASLPMSPLAKPPPQAP------PALATPPLQALPSPPASFPGQA----PFS 814

Query: 275 WSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGAT 334
            S     + L+   PQ P   +           A L    P+PP+     A RR P    
Sbjct: 815 PSASLPMSPLATPPPQAPPVLA-----------APLLQVPPSPPASPTLQAPRRPP---- 859

Query: 335 EPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDL 374
            PG  T     RL L  +PGP      +R+P+  L   DL
Sbjct: 860 TPGPDTSVSGPRLTLALAPGP--PPPPSRSPSSTLSGPDL 897


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 93/360 (25%), Positives = 121/360 (33%), Gaps = 50/360 (13%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTD---PAFGAGPLPLVSR 114
            PG + +   QG+ G +  R      G       P   G +  T    P    GP+     
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGD 1188

Query: 115  LGHAGE---RGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP 170
             G  GE   RG  GA GD         PG P P   T    PPG        P G+RG P
Sbjct: 1189 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP---TGENGPPG--------PLGKRG-P 1236

Query: 171  LGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRP 230
             G+    G   G   +  +P    +  +T     AG A +  P   R      G +  RP
Sbjct: 1237 AGSPGSEGRQGGKGAK-GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG-RP 1294

Query: 231  DAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQ 290
             A       G  G       R     +G +   PGL G + PPG   E+   GL      
Sbjct: 1295 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH-PGLIGLIGPPGEQGEKGDRGLPGPQGS 1353

Query: 291  VPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
              + G       E G P       P  P      A  +G  GAT PG             
Sbjct: 1354 PGQKG-------EMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG------------- 1393

Query: 351  RSPGPEGTSDAARAPA-PGLRDRDLRAAP-PRPRPSQRPVSG--LFKVKFFVPQSG-PGS 405
               GP+G       P  PG     ++  P   P+ ++R V G  L +    +P  G PGS
Sbjct: 1394 ---GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS 1450



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 93/354 (26%), Positives = 118/354 (33%), Gaps = 94/354 (26%)

Query: 58  PGRARAAPQQ-GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLG 116
           PG +   P + G GG  +    A       A L   R  LR         GP+    R G
Sbjct: 360 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP------GPMGYTGRPG 413

Query: 117 HAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP-L 171
             G+ GSPG    +GD+ P     P G            PPGK         GRRGR   
Sbjct: 414 PLGQPGSPGLKGESGDLGPQGPRGPQG---------LTGPPGK--------AGRRGRAGA 456

Query: 172 GAARGTGLNPGLS--------PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR 223
             ARG   +PG+         P L   +GH    R DT +             +    P 
Sbjct: 457 DGARGMPGDPGVKGDRGFDGLPGLPGEKGH----RGDTGA-------------QGLPGPP 499

Query: 224 GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
           G    R D G+     G +G       R L   +GP    PG+ G   PPG         
Sbjct: 500 GEDGERGDDGEI----GPRGLPGESGPRGLLGPKGP----PGIPG---PPGVR------- 541

Query: 284 LSRDSPQVPRSGSWAR----PCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFV 339
              D PQ P+     +    P  +QG P    L  P     A      +GP G  +PG  
Sbjct: 542 -GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQG--KPGLP 595

Query: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSGL 391
            +      P    PG EG         PG +     + P  P   P  R V G+
Sbjct: 596 GMPGSDGPP--GHPGKEG--------PPGTKGNQGPSGPQGPLGYPGPRGVKGV 639



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 78/316 (24%), Positives = 104/316 (32%), Gaps = 69/316 (21%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG A A  + G  G +    A    GT+    GP               GP+ L    G 
Sbjct: 1033 PGAAGADGEPGARGPQGHFGAKGDEGTRGFN-GP--------------PGPIGLQGLPGP 1077

Query: 118  AGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGT 177
            +GE+G    GDV P+    PPG   P         P     P+  PGG         +G 
Sbjct: 1078 SGEKGE--TGDVGPMGPPGPPGPRGPA-------GPNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 178  GLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPE 237
                G SP +Q   G +                           PRG R  + ++G+ P 
Sbjct: 1129 PGESG-SPGIQGEPGVK--------------------------GPRGERGEKGESGQ-PG 1160

Query: 238  ASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPP--GWSRERAGAGLSRDSPQVPRSG 295
              G  G +    +       GP     G  G   PP  G  R + GA   R     P   
Sbjct: 1161 EPGPPGPKGPTGDDGPKGNPGP----VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1216

Query: 296  SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGP 355
                P  E G P  L  + PA      +  R+ G G   +PG +    ++        GP
Sbjct: 1217 GSPGPTGENGPPGPLGKRGPA--GSPGSEGRQGGKGAKGDPGAIGAPGKT--------GP 1266

Query: 356  EGTSDAARAPAP-GLR 370
             G +  A  P P GLR
Sbjct: 1267 VGPAGPAGKPGPDGLR 1282



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 89/343 (25%), Positives = 114/343 (33%), Gaps = 84/343 (24%)

Query: 67  QGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA 126
           +GD G + +R      G++    GP   G + RT P    GP  L   +G  G+ G PG 
Sbjct: 661 KGDIGVKGDRGEVGVPGSRGED-GPE--GPKGRTGPTGDPGPPGL---MGEKGKLGVPGL 714

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPR 186
                      PG P                       GR+G P G+    G  PG S  
Sbjct: 715 -----------PGYP-----------------------GRQG-PKGSLGFPGF-PGAS-- 736

Query: 187 LQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGK--FPEASGGKGQ 244
                G + AR        G + +  P   R    PRG R  R   GK      SGG G 
Sbjct: 737 -----GEKGAR--------GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 783

Query: 245 RAAGAERVLNNGRGPRSRLPGLAGGVEP------PGWSRERAGAGL-SRDSPQVP----- 292
                ER L   +GP    PG  G   P      PG   +R   G   +  P  P     
Sbjct: 784 HGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842

Query: 293 --RSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
              +     P  E+GHP       P PP            G   +PG      +     L
Sbjct: 843 PQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 897

Query: 351 RS-PGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSG 390
           R  PG  G      A  PGL+  +  + PP P   P +R  +G
Sbjct: 898 RGFPGERGL--PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 938



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 60/254 (23%), Positives = 86/254 (33%), Gaps = 42/254 (16%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G    +  PG        G  G+   +    + G   A   P + G      PA  
Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275

Query: 106  AGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRP-------------DPLLLTTFVF 151
             GP  L    G  G++G PGA G   P     PPG P              P L+   + 
Sbjct: 1276 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLI-GLIG 1334

Query: 152  PPGKTS--------APRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS 203
            PPG+           P+ SPG +    +  A G  + PG  P L  P G + A+      
Sbjct: 1335 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAK------ 1387

Query: 204  RAGWATRRAPSRRRNFGAPRG-----SRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRG 258
              G      P   +    P G        ++P   + P+    K +R+    R++     
Sbjct: 1388 --GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPK----KTRRSVDGSRLMQEDEA 1441

Query: 259  -PRSRLPGLAGGVE 271
             P    PG  GG+E
Sbjct: 1442 IPTGGAPGSPGGLE 1455


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 93/360 (25%), Positives = 121/360 (33%), Gaps = 50/360 (13%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTD---PAFGAGPLPLVSR 114
            PG + +   QG+ G +  R      G       P   G +  T    P    GP+     
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGD 1167

Query: 115  LGHAGE---RGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP 170
             G  GE   RG  GA GD         PG P P   T    PPG        P G+RG P
Sbjct: 1168 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP---TGENGPPG--------PLGKRG-P 1215

Query: 171  LGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRP 230
             G+    G   G   +  +P    +  +T     AG A +  P   R      G +  RP
Sbjct: 1216 AGSPGSEGRQGGKGAK-GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG-RP 1273

Query: 231  DAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQ 290
             A       G  G       R     +G +   PGL G + PPG   E+   GL      
Sbjct: 1274 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH-PGLIGLIGPPGEQGEKGDRGLPGPQGS 1332

Query: 291  VPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
              + G       E G P       P  P      A  +G  GAT PG             
Sbjct: 1333 PGQKG-------EMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG------------- 1372

Query: 351  RSPGPEGTSDAARAPA-PGLRDRDLRAAP-PRPRPSQRPVSG--LFKVKFFVPQSG-PGS 405
               GP+G       P  PG     ++  P   P+ ++R V G  L +    +P  G PGS
Sbjct: 1373 ---GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS 1429



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 93/354 (26%), Positives = 118/354 (33%), Gaps = 94/354 (26%)

Query: 58  PGRARAAPQQ-GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLG 116
           PG +   P + G GG  +    A       A L   R  LR         GP+    R G
Sbjct: 339 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP------GPMGYTGRPG 392

Query: 117 HAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP-L 171
             G+ GSPG    +GD+ P     P G            PPGK         GRRGR   
Sbjct: 393 PLGQPGSPGLKGESGDLGPQGPRGPQG---------LTGPPGK--------AGRRGRAGA 435

Query: 172 GAARGTGLNPGLS--------PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR 223
             ARG   +PG+         P L   +GH    R DT +             +    P 
Sbjct: 436 DGARGMPGDPGVKGDRGFDGLPGLPGEKGH----RGDTGA-------------QGLPGPP 478

Query: 224 GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
           G    R D G+     G +G       R L   +GP    PG+ G   PPG         
Sbjct: 479 GEDGERGDDGEI----GPRGLPGESGPRGLLGPKGP----PGIPG---PPGVR------- 520

Query: 284 LSRDSPQVPRSGSWAR----PCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFV 339
              D PQ P+     +    P  +QG P    L  P     A      +GP G  +PG  
Sbjct: 521 -GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQG--KPGLP 574

Query: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSGL 391
            +      P    PG EG         PG +     + P  P   P  R V G+
Sbjct: 575 GMPGSDGPP--GHPGKEG--------PPGTKGNQGPSGPQGPLGYPGPRGVKGV 618



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 78/316 (24%), Positives = 104/316 (32%), Gaps = 69/316 (21%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG A A  + G  G +    A    GT+    GP               GP+ L    G 
Sbjct: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFN-GP--------------PGPIGLQGLPGP 1056

Query: 118  AGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGT 177
            +GE+G    GDV P+    PPG   P         P     P+  PGG         +G 
Sbjct: 1057 SGEKGE--TGDVGPMGPPGPPGPRGPA-------GPNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 178  GLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPE 237
                G SP +Q   G +                           PRG R  + ++G+ P 
Sbjct: 1108 PGESG-SPGIQGEPGVK--------------------------GPRGERGEKGESGQ-PG 1139

Query: 238  ASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPP--GWSRERAGAGLSRDSPQVPRSG 295
              G  G +    +       GP     G  G   PP  G  R + GA   R     P   
Sbjct: 1140 EPGPPGPKGPTGDDGPKGNPGP----VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1195

Query: 296  SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGP 355
                P  E G P  L  + PA      +  R+ G G   +PG +    ++        GP
Sbjct: 1196 GSPGPTGENGPPGPLGKRGPA--GSPGSEGRQGGKGAKGDPGAIGAPGKT--------GP 1245

Query: 356  EGTSDAARAPAP-GLR 370
             G +  A  P P GLR
Sbjct: 1246 VGPAGPAGKPGPDGLR 1261



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 89/343 (25%), Positives = 114/343 (33%), Gaps = 84/343 (24%)

Query: 67  QGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA 126
           +GD G + +R      G++    GP   G + RT P    GP  L   +G  G+ G PG 
Sbjct: 640 KGDIGVKGDRGEVGVPGSRGED-GPE--GPKGRTGPTGDPGPPGL---MGEKGKLGVPGL 693

Query: 127 GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPR 186
                      PG P                       GR+G P G+    G  PG S  
Sbjct: 694 -----------PGYP-----------------------GRQG-PKGSLGFPGF-PGAS-- 715

Query: 187 LQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGK--FPEASGGKGQ 244
                G + AR        G + +  P   R    PRG R  R   GK      SGG G 
Sbjct: 716 -----GEKGAR--------GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 762

Query: 245 RAAGAERVLNNGRGPRSRLPGLAGGVEP------PGWSRERAGAGL-SRDSPQVP----- 292
                ER L   +GP    PG  G   P      PG   +R   G   +  P  P     
Sbjct: 763 HGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821

Query: 293 --RSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
              +     P  E+GHP       P PP            G   +PG      +     L
Sbjct: 822 PQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 876

Query: 351 RS-PGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSG 390
           R  PG  G      A  PGL+  +  + PP P   P +R  +G
Sbjct: 877 RGFPGERGL--PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 917



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 60/254 (23%), Positives = 86/254 (33%), Gaps = 42/254 (16%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G    +  PG        G  G+   +    + G   A   P + G      PA  
Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254

Query: 106  AGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRP-------------DPLLLTTFVF 151
             GP  L    G  G++G PGA G   P     PPG P              P L+   + 
Sbjct: 1255 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLI-GLIG 1313

Query: 152  PPGKTS--------APRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS 203
            PPG+           P+ SPG +    +  A G  + PG  P L  P G + A+      
Sbjct: 1314 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAK------ 1366

Query: 204  RAGWATRRAPSRRRNFGAPRG-----SRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRG 258
              G      P   +    P G        ++P   + P+    K +R+    R++     
Sbjct: 1367 --GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPK----KTRRSVDGSRLMQEDEA 1420

Query: 259  -PRSRLPGLAGGVE 271
             P    PG  GG+E
Sbjct: 1421 IPTGGAPGSPGGLE 1434


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 93/360 (25%), Positives = 121/360 (33%), Gaps = 50/360 (13%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTD---PAFGAGPLPLVSR 114
            PG + +   QG+ G +  R      G       P   G +  T    P    GP+     
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGD 1274

Query: 115  LGHAGE---RGSPGA-GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP 170
             G  GE   RG  GA GD         PG P P   T    PPG        P G+RG P
Sbjct: 1275 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP---TGENGPPG--------PLGKRG-P 1322

Query: 171  LGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRP 230
             G+    G   G   +  +P    +  +T     AG A +  P   R      G +  RP
Sbjct: 1323 AGSPGSEGRQGGKGAK-GDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQG-RP 1380

Query: 231  DAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQ 290
             A       G  G       R     +G +   PGL G + PPG   E+   GL      
Sbjct: 1381 GATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH-PGLIGLIGPPGEQGEKGDRGLPGPQGS 1439

Query: 291  VPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
              + G       E G P       P  P      A  +G  GAT PG             
Sbjct: 1440 PGQKG-------EMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG------------- 1479

Query: 351  RSPGPEGTSDAARAPA-PGLRDRDLRAAP-PRPRPSQRPVSG--LFKVKFFVPQSG-PGS 405
               GP+G       P  PG     ++  P   P+ ++R V G  L +    +P  G PGS
Sbjct: 1480 ---GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGS 1536



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 93/354 (26%), Positives = 118/354 (33%), Gaps = 94/354 (26%)

Query: 58  PGRARAAPQQ-GDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLG 116
           PG +   P + G GG  +    A       A L   R  LR         GP+    R G
Sbjct: 446 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP------GPMGYTGRPG 499

Query: 117 HAGERGSPG----AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP-L 171
             G+ GSPG    +GD+ P     P G            PPGK         GRRGR   
Sbjct: 500 PLGQPGSPGLKGESGDLGPQGPRGPQG---------LTGPPGK--------AGRRGRAGA 542

Query: 172 GAARGTGLNPGLS--------PRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPR 223
             ARG   +PG+         P L   +GH    R DT +             +    P 
Sbjct: 543 DGARGMPGDPGVKGDRGFDGLPGLPGEKGH----RGDTGA-------------QGLPGPP 585

Query: 224 GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAG 283
           G    R D G+     G +G       R L   +GP    PG+ G   PPG         
Sbjct: 586 GEDGERGDDGEI----GPRGLPGESGPRGLLGPKGP----PGIPG---PPGVR------- 627

Query: 284 LSRDSPQVPRSGSWAR----PCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFV 339
              D PQ P+     +    P  +QG P    L  P     A      +GP G  +PG  
Sbjct: 628 -GMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG---AIGPHGEKGPQG--KPGLP 681

Query: 340 TLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSGL 391
            +      P    PG EG         PG +     + P  P   P  R V G+
Sbjct: 682 GMPGSDGPP--GHPGKEG--------PPGTKGNQGPSGPQGPLGYPGPRGVKGV 725



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 78/316 (24%), Positives = 104/316 (32%), Gaps = 69/316 (21%)

Query: 58   PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
            PG A A  + G  G +    A    GT+    GP               GP+ L    G 
Sbjct: 1119 PGAAGADGEPGARGPQGHFGAKGDEGTRGFN-GP--------------PGPIGLQGLPGP 1163

Query: 118  AGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGT 177
            +GE+G    GDV P+    PPG   P         P     P+  PGG         +G 
Sbjct: 1164 SGEKGE--TGDVGPMGPPGPPGPRGPA-------GPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 178  GLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPE 237
                G SP +Q   G +                           PRG R  + ++G+ P 
Sbjct: 1215 PGESG-SPGIQGEPGVK--------------------------GPRGERGEKGESGQ-PG 1246

Query: 238  ASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPP--GWSRERAGAGLSRDSPQVPRSG 295
              G  G +    +       GP     G  G   PP  G  R + GA   R     P   
Sbjct: 1247 EPGPPGPKGPTGDDGPKGNPGP----VGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQP 1302

Query: 296  SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGP 355
                P  E G P  L  + PA      +  R+ G G   +PG +    ++        GP
Sbjct: 1303 GSPGPTGENGPPGPLGKRGPA--GSPGSEGRQGGKGAKGDPGAIGAPGKT--------GP 1352

Query: 356  EGTSDAARAPAP-GLR 370
             G +  A  P P GLR
Sbjct: 1353 VGPAGPAGKPGPDGLR 1368



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 89/343 (25%), Positives = 114/343 (33%), Gaps = 84/343 (24%)

Query: 67   QGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGA 126
            +GD G + +R      G++    GP   G + RT P    GP  L   +G  G+ G PG 
Sbjct: 747  KGDIGVKGDRGEVGVPGSRGED-GPE--GPKGRTGPTGDPGPPGL---MGEKGKLGVPGL 800

Query: 127  GDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPR 186
                       PG P                       GR+G P G+    G  PG S  
Sbjct: 801  -----------PGYP-----------------------GRQG-PKGSLGFPGF-PGAS-- 822

Query: 187  LQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGK--FPEASGGKGQ 244
                 G + AR        G + +  P   R    PRG R  R   GK      SGG G 
Sbjct: 823  -----GEKGAR--------GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 869

Query: 245  RAAGAERVLNNGRGPRSRLPGLAGGVEP------PGWSRERAGAGL-SRDSPQVP----- 292
                 ER L   +GP    PG  G   P      PG   +R   G   +  P  P     
Sbjct: 870  HGPPGERGLPGPQGPNG-FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 928

Query: 293  --RSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLL 350
               +     P  E+GHP       P PP            G   +PG      +     L
Sbjct: 929  PQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983

Query: 351  RS-PGPEGTSDAARAPAPGLRDRDLRAAPPRP--RPSQRPVSG 390
            R  PG  G      A  PGL+  +  + PP P   P +R  +G
Sbjct: 984  RGFPGERGL--PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAG 1024



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 60/254 (23%), Positives = 86/254 (33%), Gaps = 42/254 (16%)

Query: 46   PHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFG 105
            P   G    +  PG        G  G+   +    + G   A   P + G      PA  
Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361

Query: 106  AGPLPLVSRLGHAGERGSPGA-GDVNPVSASSPPGRP-------------DPLLLTTFVF 151
             GP  L    G  G++G PGA G   P     PPG P              P L+   + 
Sbjct: 1362 PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLI-GLIG 1420

Query: 152  PPGKTS--------APRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS 203
            PPG+           P+ SPG +    +  A G  + PG  P L  P G + A+      
Sbjct: 1421 PPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP-IGPGGPPGLPGPAGPKGAK------ 1473

Query: 204  RAGWATRRAPSRRRNFGAPRG-----SRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRG 258
              G      P   +    P G        ++P   + P+    K +R+    R++     
Sbjct: 1474 --GATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPK----KTRRSVDGSRLMQEDEA 1527

Query: 259  -PRSRLPGLAGGVE 271
             P    PG  GG+E
Sbjct: 1528 IPTGGAPGSPGGLE 1541


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 105/384 (27%), Positives = 132/384 (34%), Gaps = 94/384 (24%)

Query: 108 PLPLVSRLGHAGERGSPGAGDVNPVSASSPPG---------RPDPLLLTTF------VFP 152
           P P  +  G AG RGS   GD      +  PG         R D L ++T         P
Sbjct: 32  PSPSAAAAGAAGARGSE-TGDPGSPRGAEEPGKKRHERLFHRQDALWISTSSAGTGGAEP 90

Query: 153 PGKTSAP-------RPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRA 205
           P  + AP        P+P GRR        G  L+ GLSP   +P G  ++ R    S  
Sbjct: 91  PALSPAPASPARPVSPAP-GRRLSLWAVPPGPPLSGGLSPD-PKPGGAPTSSRRPLLSSP 148

Query: 206 GWATRRAPSRRRNFGAP--------RGSRRLR----PDAGK--------FPEASGGKG-- 243
            W     P  R   G P         GSRRL+    P A K          +A GGKG  
Sbjct: 149 SWGGPE-PEGRAGGGIPGSSSPHPGTGSRRLKVAPPPPAPKPCKTVTTSGAKAGGGKGAG 207

Query: 244 -----------QRAAGAERVLNNGRG-PRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQV 291
                       R  G++     G     +     AGG      +    GAG        
Sbjct: 208 SRLSWPESEGKPRVKGSKSSAGTGASVSAAATAAAAGGGGSTASTSGGVGAGAGARGKLS 267

Query: 292 PRSG-------SWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFR 344
           PR G       S   P    G P  L L     P+ A  AA  + PG A           
Sbjct: 268 PRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSPATAVTAASAQPPGPAP---------- 317

Query: 345 SRLPLLRSPGPEGTSDAARAPAPGL-RDRDLRAAPPRPRPSQRPVSGLF-KVKFFVPQSG 402
              P+   P           PAPGL R R+   A  R R   + +SG+F K     P SG
Sbjct: 318 ---PITLEP-----------PAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPPGSG 363

Query: 403 PGSSACEVAVPTTAGRELLGSEPR 426
           P      ++   +  RELLG+E R
Sbjct: 364 PLPGPPSLS-SGSGSRELLGAELR 386


>gi|239756562 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 235

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 53/187 (28%), Positives = 74/187 (39%), Gaps = 32/187 (17%)

Query: 163 PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTAS-RAGWATRR----APSRRR 217
           P GRR  P  + RG  + P  +  L   RG    R    A+ +AG   RR     P  R 
Sbjct: 51  PAGRR--PCASHRGRRITPATALLLLSHRGRAERRSMQAAAAKAGSPGRRRVGKGPPSRE 108

Query: 218 NFGAPRGSRRLRPDAGKF--------PEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGG 269
           ++      R    DAG+         P++ GG+   A+GA+R    G+ PR + P  AG 
Sbjct: 109 SWTRSAPQRCPSQDAGRAGSRVCRSRPQSRGGQKAAASGAKRRGVGGKEPRRQKPAAAGA 168

Query: 270 VEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRG 329
                    ++  G S   P+  R G  A P +  G           P   A A A+ RG
Sbjct: 169 ---------KSRGGKSHKKPR--RRGQKAAPAKNSGG------GGNKPQKAAAAGAKNRG 211

Query: 330 PGGATEP 336
            GG  +P
Sbjct: 212 GGGGKKP 218


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 96/346 (27%), Positives = 115/346 (33%), Gaps = 52/346 (15%)

Query: 90  GPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPG----------------AGDVNPVS 133
           G  + GL  +  PA   GP P  SR+G AG  G PG                 GD     
Sbjct: 101 GMGKPGLHGQPGPA---GP-PGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRG 156

Query: 134 ASSPPGRPDPLLLTTFVFPPGKTSAPR-PSPGGRRGRPLGAARGTGLNPGLSPRLQEPRG 192
              PPG P P  +T     PGK  A   P P G +G P     G    PG  P  +  +G
Sbjct: 157 PPGPPGLPGPSGITI----PGKPGAQGVPGPPGFQGEP-----GPQGEPG-PPGDRGLKG 206

Query: 193 HQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERV 252
                +       G      P      G P  +   +P     P A G KG+  +G   V
Sbjct: 207 DNGVGQPGLPGAPGQGGAPGPP-----GLPGPAGLGKPGLDGLPGAPGDKGE--SGPPGV 259

Query: 253 LNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLAL 312
                GPR   PG  G   PPG              PQ P SG+   P   +G P ++  
Sbjct: 260 ----PGPRGE-PGAVGPKGPPGVDGVGVPGAAGLPGPQGP-SGAKGEP-GTRGPPGLIGP 312

Query: 313 QSPAPPSLARAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPA-PGLRD 371
                P L       RGP G   PG   L  R        PG +G       P  PG   
Sbjct: 313 TGYGMPGLP-GPKGDRGPAGV--PGL--LGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAG 367

Query: 372 RDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPGSSACEVAVPTTAG 417
              R  PP P+    P  G   V       GP   A +  VP   G
Sbjct: 368 LPGRRGPPGPKGEAGP-GGPPGVPGIRGDQGPSGLAGKPGVPGERG 412



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 79/294 (26%), Positives = 94/294 (31%), Gaps = 56/294 (19%)

Query: 58  PGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGH 117
           PG A     QG  GA+ E       G     +GP   G+     P    GP  +   LG 
Sbjct: 283 PGAAGLPGPQGPSGAKGEPGTRGPPGL----IGPTGYGMPGLPGPKGDRGPAGVPGLLGD 338

Query: 118 AGERGSPG-AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRP----SPGGRRGRP-- 170
            GE G  G  G+  P     PPG P    L      PG+   P P     PGG  G P  
Sbjct: 339 RGEPGEDGEPGEQGPQGLGGPPGLPGSAGL------PGRRGPPGPKGEAGPGGPPGVPGI 392

Query: 171 LGAARGTGL--NPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRL 228
            G    +GL   PG+      P  H     T      G+            G P G    
Sbjct: 393 RGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFT-----------GRPGG---- 437

Query: 229 RPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGL---AGGVEPPGWSRERAGAGLS 285
                  P  +G  GQ+           RGP S +PGL   AG + P G    +   GL 
Sbjct: 438 -------PGVAGALGQKGDLGLPGQPGLRGP-SGIPGLQGPAGPIGPQGLPGLKGEPGL- 488

Query: 286 RDSPQVPRSGSWARP--CREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPG 337
              P  P  G    P      G P V     P  P +         PG    PG
Sbjct: 489 ---PGPPGEGRAGEPGTAGPTGPPGV-----PGSPGITGPPGPPGPPGPPGAPG 534



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 88/336 (26%), Positives = 107/336 (31%), Gaps = 42/336 (12%)

Query: 64  APQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGS 123
           AP QG             LG       P   G +  + P    GP       G  G +G 
Sbjct: 218 APGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPR---GEPGAVGPKGP 274

Query: 124 PG---------AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPLGAA 174
           PG         AG   P   S   G P        + P G      P P G RG P G  
Sbjct: 275 PGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRG-PAGVP 333

Query: 175 -----RGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF---GAPRGSR 226
                RG     G  P  Q P+G            AG   RR P   +     G P G  
Sbjct: 334 GLLGDRGEPGEDG-EPGEQGPQG--LGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP 390

Query: 227 RLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSR 286
            +R D G     SG  G+     ER L    GP    PG  G    PG++    G G++ 
Sbjct: 391 GIRGDQG----PSGLAGKPGVPGERGLPGAHGP----PGPTGPKGEPGFTGRPGGPGVAG 442

Query: 287 DSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGFVTLAFRSR 346
              Q    G   +P   +G   +  LQ PA P   +       PG   EPG        R
Sbjct: 443 ALGQKGDLGLPGQP-GLRGPSGIPGLQGPAGPIGPQGL-----PGLKGEPGLPGPPGEGR 496

Query: 347 LPLLRSPGPEGTSDAARAP-APGLRDRDLRAAPPRP 381
                 PG  G +     P +PG+        PP P
Sbjct: 497 ---AGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGP 529



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 44/134 (32%), Positives = 49/134 (36%), Gaps = 26/134 (19%)

Query: 50  GAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPL 109
           G   R   PG A A  Q+GD G          L  Q    GP   G+     PA   GP 
Sbjct: 430 GFTGRPGGPGVAGALGQKGDLG----------LPGQPGLRGP--SGIPGLQGPAGPIGPQ 477

Query: 110 PLVSRLGHAGERGSPG---AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAP-RPSPGG 165
            L    G  G  G PG   AG+      + PPG P           PG T  P  P P G
Sbjct: 478 GLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPG---------SPGITGPPGPPGPPG 528

Query: 166 RRGRPLGAARGTGL 179
             G P GA   TG+
Sbjct: 529 PPGAP-GAFDETGI 541


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 100/415 (24%), Positives = 142/415 (34%), Gaps = 65/415 (15%)

Query: 7   AESRDHRARLRTLSEARPGDWERRAGSSLCGSAEALLLSPHVTGAAQRSPTPGRARAAP- 65
           + SR   A  +T + A  G     A S   G  +A    P  T + QR  +P  A   P 
Sbjct: 275 SRSRSRSAAAKTHTTALAGRSPSPA-SGRRGEGDAPFSEPGTT-STQRPSSPETATKQPS 332

Query: 66  ---QQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLV---------- 112
              +  D   + + A   S   + ++ GP             G  P PL           
Sbjct: 333 SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVN 392

Query: 113 --SRLGHAGERGSPGAGDVNPVSASSP--PGRPDPLLLTTFVFPPGKTSAPRPSPGGRR- 167
             S      +R  P + +  P S+SS   P  P P  ++       ++  P P+PG  R 
Sbjct: 393 PPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452

Query: 168 --------GRPLG-AARGTGLNPGLSPRLQEPRGHQSAR----RTDTASRAGWATRRAPS 214
                    R  G A R    +   S R+   R   +A+    R+ T ++ G +  R+P 
Sbjct: 453 ISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512

Query: 215 RRRNFGAPR------GSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
            RR+  A R        RR R  + + P  S  +  +  G  R    GR   SR P   G
Sbjct: 513 WRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRS-HSRSPATRG 571

Query: 269 GVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRR 328
                  SR  A  G SR      R      P R +      A +     S +R  ARRR
Sbjct: 572 RSR----SRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRG---RSRSRTPARRR 624

Query: 329 GPGGATEPGFVTLAFRSRLPL---LRSPGPEGTSDAARAPAPGLRDRDLRAAPPR 380
                          R+R P+    RS  P   S  +R+  P  R R     P R
Sbjct: 625 S--------------RTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 79/365 (21%), Positives = 115/365 (31%), Gaps = 39/365 (10%)

Query: 45   SPHVTGAAQRSPTPGRA--RAAPQQGDGGARRERAAAESLGTQSATLGP---------RR 93
            +P     +  SP P     RA P++   G+  +       G+ S    P         RR
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 94   GG-------LRSRTDPAFGAG-PLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLL 145
            G         +SRT P   +    P ++R      R    +      S + P  R  P +
Sbjct: 1671 GSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730

Query: 146  LTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPR-LQEPRGHQSARRTDTA-- 202
             +       ++S  R S    R +        G +P   PR LQ  R      +T T   
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRR---GRSPSPKPRGLQRSRSRSRREKTRTTRR 1787

Query: 203  -SRAGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRS 261
              R+G +   +  R+R+    R +RR R  +G    +   +      + R     R P +
Sbjct: 1788 RDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPT 1847

Query: 262  RLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLA 321
                      P  W R R     SR SP   R      P   +              S +
Sbjct: 1848 SRKRSRSRTSPAPWKRSR-----SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRS 1902

Query: 322  RAAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRP 381
            R +  RR       P       R R    RS  P  T   +R+  P  R R     PP  
Sbjct: 1903 RTSVTRRRSRSRASP-----VSRRR---SRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVT 1954

Query: 382  RPSQR 386
            R   R
Sbjct: 1955 RRRSR 1959



 Score = 35.4 bits (80), Expect = 0.11
 Identities = 55/247 (22%), Positives = 80/247 (32%), Gaps = 56/247 (22%)

Query: 155 KTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPS 214
           ++ +  P+P  RR     A R T  +   S      R   +A +T T + AG    R+PS
Sbjct: 247 RSRSTTPAPKSRR-----AHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG----RSPS 297

Query: 215 RRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPG 274
                  P   RR   DA  F E      QR +  E        P               
Sbjct: 298 -------PASGRRGEGDA-PFSEPGTTSTQRPSSPETATKQPSSPYEDK----------- 338

Query: 275 WSRERAGAGLSRDSPQVPRSGSWARPC--------REQGHPAVLAL----QSPAPPSLAR 322
             +++     +R SP   RS +   P         R  G P  LA     Q P  P    
Sbjct: 339 -DKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEA 397

Query: 323 AAARRRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPR 382
           +  R R P  + E               + P    +  +  +P P    R   ++P  P+
Sbjct: 398 SPTRDRSPPKSPE---------------KLPQSSSSESSPPSPQPTKVSRHASSSPESPK 442

Query: 383 PSQRPVS 389
           P+  P S
Sbjct: 443 PAPAPGS 449



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 114/488 (23%), Positives = 167/488 (34%), Gaps = 105/488 (21%)

Query: 4   RAAAESRDH------RARLRTLSEARPG------DWERRAGSSLCGSAEALLLSPHVTGA 51
           R+A   R H      R R R+ + AR G         RR+ S       +   +P   G 
Sbjct: 555 RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614

Query: 52  AQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPL 111
           + RS TP R R+  +       R R+ A   G   +    RRG  RSRT    G      
Sbjct: 615 S-RSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR----- 668

Query: 112 VSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRPL 171
                                S S  P R              ++   R     RRGR  
Sbjct: 669 ---------------------SRSRTPAR--------------RSGRSRSRTPARRGR-- 691

Query: 172 GAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGSRRLRPD 231
                   +   +PR    R     RR  + SR      R+ S        R S+R R  
Sbjct: 692 --------SRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQR-RSR 742

Query: 232 AGKFPEASGGKGQRAAGAERVLNNGRG-PRSRLP---GLAGGVEPPGWS------RERAG 281
           +   PE    K + ++   R L++ R   +SRL     L+G    P         R R+G
Sbjct: 743 SNSSPEMK--KSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG 800

Query: 282 A----GLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAP-PSLARAAARRRGPGGATEP 336
           +      SR  P+  RS S   P ++   P+  +  S +P P +      R+G   + + 
Sbjct: 801 SSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQA 860

Query: 337 GFVTLAFRSRLPLLRSPGPE--GTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKV 394
              ++  + R     SP PE    + +  + +     R   + PPR  PS R  S   KV
Sbjct: 861 NEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS-RSSSPQPKV 919

Query: 395 KFFV---PQSGPGSSACEVAVPTTAGRELLGSEPRNGTLESICSLHVGNGARAHVLELHP 451
           K  +    +S  GSS+       +  R    + PR     S CS             +  
Sbjct: 920 KAIISPRQRSHSGSSS------PSPSRVTSRTTPRRSRSVSPCS------------NVES 961

Query: 452 RSLSQYSH 459
           R L +YSH
Sbjct: 962 RLLPRYSH 969


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 92/362 (25%), Positives = 123/362 (33%), Gaps = 45/362 (12%)

Query: 39  AEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRS 98
           A A   +P        +P P  +   P      A R   AA ++G +   L  R GG+  
Sbjct: 10  AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKP--LAERAGGIGG 67

Query: 99  RTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPD--PLLLTTFVFP---P 153
            T P               AG   S G    NP S     GR +  P    T   P   P
Sbjct: 68  ATIPESAP----------RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP 117

Query: 154 GKTSAP-RPSPGGRRGRPLGA----ARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWA 208
           G+ S   RP P G++G  + A    ARG          L        ARR  +    G  
Sbjct: 118 GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA-----GARRDTSGPTPGTP 172

Query: 209 TRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAG 268
           +     R R  G   G  R  P A   P   G +   ++ +E           R P   G
Sbjct: 173 SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG 232

Query: 269 GVEPPGWSRERAGAGLSRDSPQVPRSGSWARPC-REQGHPA---VLALQSPAPPSLA--- 321
           G++ P  SR  + +     SP   RSG  AR   R   HP+      LQ+  PP +    
Sbjct: 233 GLQRPA-SRSLSSSATPLSSP--ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR 289

Query: 322 RAAARRRGP--GGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPP 379
           + AA   GP           + A +S+ P      P  +S   +   P      L  APP
Sbjct: 290 KDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP------LPLAPP 343

Query: 380 RP 381
            P
Sbjct: 344 SP 345



 Score = 35.0 bits (79), Expect = 0.14
 Identities = 41/163 (25%), Positives = 56/163 (34%), Gaps = 16/163 (9%)

Query: 277 RERAGAGLSRDSPQV-------PRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRG 329
           R++A AG +  +P         PR     RP       A+  L +         A R  G
Sbjct: 5   RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64

Query: 330 PGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVS 389
            GGAT P     A  +R     S G    + A+R PA G  +R    APP    S  PVS
Sbjct: 65  IGGATIPESAPRAGPTR-----SAGTSSRNPASRPPASGRGER----APPAKNTSPGPVS 115

Query: 390 GLFKVKFFVPQSGPGSSACEVAVPTTAGRELLGSEPRNGTLES 432
              +          G     ++   T  R      P+   L +
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSA 158


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 100/373 (26%), Positives = 128/373 (34%), Gaps = 74/373 (19%)

Query: 27  WERRAGSSLC--GSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGT 84
           WE+R+   L   GS  +LL S     A + +P      AA  +G GGA R  A   +   
Sbjct: 198 WEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSA--- 254

Query: 85  QSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPL 144
           Q   L             +    P PL  RLG A                 SPP    PL
Sbjct: 255 QQPPLARLLLASAVSLAASLARSPPPLQPRLGSA-----------------SPPRLAAPL 297

Query: 145 LLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASR 204
                      + AP  SP  RR R        G    L   L        ARR     R
Sbjct: 298 ---------AGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARR-----R 343

Query: 205 AGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGP----- 259
            G   RR   RR+  G   GS    P     P A G  G+R A A +    G GP     
Sbjct: 344 RGGEERRVRGRRQ--GCALGS----PPIPAGPAAPGRAGERRA-ARQWRKRGGGPGVSPR 396

Query: 260 -RSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPP 318
             ++  G+ GGV P    R R  +   R SP      +W      QG     A+ +  P 
Sbjct: 397 EGAQGEGVRGGVTP----RARGSSTCLRPSP-----ATW------QGGAPYRAIFAAGPR 441

Query: 319 SLARAAARRRGPGG--ATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLR--DRDL 374
             A +A     PGG  A+ P +  L+ R      R+  P    D+  +PA      DR+ 
Sbjct: 442 LSAPSAEAEEVPGGHTASNPTYEPLSSR------RTKAPSEGRDSPSSPATSTHYLDRES 495

Query: 375 RAAPPRPRPSQRP 387
                   PS+ P
Sbjct: 496 GLGSVNSHPSRSP 508



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 66/235 (28%), Positives = 88/235 (37%), Gaps = 41/235 (17%)

Query: 3   LRAAAESRDHRARLRTLSEARPGDWERRAGS--SLCGSAEA-----LLLSPHVTGAAQ-- 53
           L +A  +R  R   R   EA  G   R      +  GSA+      LLL+  V+ AA   
Sbjct: 216 LPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLA 275

Query: 54  RSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVS 113
           RSP P + R       G A   R AA   G+++ +L P     R R + +     LPL  
Sbjct: 276 RSPPPLQPRL------GSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPR 329

Query: 114 RLGHAGE-------RGSPG---AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS- 162
            L   GE       RG       G     +  SPP    P         PG+    R + 
Sbjct: 330 SLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPA-------APGRAGERRAAR 382

Query: 163 -----PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRA 212
                 GG    P   A+G G+  G++PR    RG  +  R   A+  G A  RA
Sbjct: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPR---ARGSSTCLRPSPATWQGGAPYRA 434



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 73/291 (25%), Positives = 102/291 (35%), Gaps = 50/291 (17%)

Query: 91  PRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFV 150
           PR  G+   +      GP PLV          +  AG++     ++P     P L  +  
Sbjct: 51  PRARGVEVASGRTRWTGPQPLVDT------PPARRAGELCEAPQTAPGFHFQPFLSLSPH 104

Query: 151 FPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATR 210
              G++    P  G RRG+      G G +P   P+               A+R    + 
Sbjct: 105 QERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQ-------------RLAARRWLHSP 151

Query: 211 RAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGV 270
           R P+      AP       P  G  P++                  R P +  PG   G 
Sbjct: 152 REPTPPGRLSAP-------PRHGPHPQSF-----------------RRPSAHPPGRGSGR 187

Query: 271 EPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGP 330
            P G   ++A     R S  +   GS A        PA      PAP +   AAA  RG 
Sbjct: 188 VPRGQPEQQAWE--QRSSHFLAPEGSVA-SLLPSAKPA--RAPRPAPRAREEAAAGSRGR 242

Query: 331 GGATEPGFVTLAFRSRLP-LLRSPGPEGTSDAARAPAPGLRDRDLRAAPPR 380
           GGA  P     A +  L  LL +      +  AR+P P L+ R   A+PPR
Sbjct: 243 GGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPP-LQPRLGSASPPR 292


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 95/359 (26%), Positives = 121/359 (33%), Gaps = 65/359 (18%)

Query: 43  LLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLG-TQSATL---GPRRGGLRS 98
           LL+P   G+  R P P    A    G  GA   +  AE  G    AT+    PR G  R+
Sbjct: 24  LLTPRPPGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82

Query: 99  RTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSA 158
              PA G G            ER  P A + +P   SSP GR               +  
Sbjct: 83  SRPPASGRG------------ERAPP-AKNTSPGPVSSP-GRA--------------SGT 114

Query: 159 PRPSPGGRRGRPLGA----ARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPS 214
            RP P G++G  + A    ARG          L        ARR  +    G  +     
Sbjct: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSA-----GARRDTSGPTPGTPSPAMAR 169

Query: 215 RRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPG 274
           R R  G   G  R  P A   P   G +   ++ +E           R P   GG++ P 
Sbjct: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPA 229

Query: 275 WSRERAGAGLSRDSPQVPRSGSWARPC-REQGHPAVLALQSPAPPSLARAAARRRGPGGA 333
            SR  + +     SP   RSG  AR   R   HP+      P P  L            A
Sbjct: 230 -SRSLSSSATPLSSP--ARSGPSARGTPRAPAHPS-----QPKPKGLQ-----------A 270

Query: 334 TEPGFVTLAFRSRLPLL--RSPGPEGTSDAARAPAPGL-RDRDLRAAPPRPRPSQRPVS 389
             P  VT   +   P L   S  P  T   +  P+P          +PP   PSQ   S
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 100/373 (26%), Positives = 128/373 (34%), Gaps = 74/373 (19%)

Query: 27  WERRAGSSLC--GSAEALLLSPHVTGAAQRSPTPGRARAAPQQGDGGARRERAAAESLGT 84
           WE+R+   L   GS  +LL S     A + +P      AA  +G GGA R  A   +   
Sbjct: 198 WEQRSSHFLAPEGSVASLLPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSA--- 254

Query: 85  QSATLGPRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPL 144
           Q   L             +    P PL  RLG A                 SPP    PL
Sbjct: 255 QQPPLARLLLASAVSLAASLARSPPPLQPRLGSA-----------------SPPRLAAPL 297

Query: 145 LLTTFVFPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASR 204
                      + AP  SP  RR R        G    L   L        ARR     R
Sbjct: 298 ---------AGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARR-----R 343

Query: 205 AGWATRRAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGP----- 259
            G   RR   RR+  G   GS    P     P A G  G+R A A +    G GP     
Sbjct: 344 RGGEERRVRGRRQ--GCALGS----PPIPAGPAAPGRAGERRA-ARQWRKRGGGPGVSPR 396

Query: 260 -RSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPP 318
             ++  G+ GGV P    R R  +   R SP      +W      QG     A+ +  P 
Sbjct: 397 EGAQGEGVRGGVTP----RARGSSTCLRPSP-----ATW------QGGAPYRAIFAAGPR 441

Query: 319 SLARAAARRRGPGG--ATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLR--DRDL 374
             A +A     PGG  A+ P +  L+ R      R+  P    D+  +PA      DR+ 
Sbjct: 442 LSAPSAEAEEVPGGHTASNPTYEPLSSR------RTKAPSEGRDSPSSPATSTHYLDRES 495

Query: 375 RAAPPRPRPSQRP 387
                   PS+ P
Sbjct: 496 GLGSVNSHPSRSP 508



 Score = 38.9 bits (89), Expect = 0.010
 Identities = 66/235 (28%), Positives = 88/235 (37%), Gaps = 41/235 (17%)

Query: 3   LRAAAESRDHRARLRTLSEARPGDWERRAGS--SLCGSAEA-----LLLSPHVTGAAQ-- 53
           L +A  +R  R   R   EA  G   R      +  GSA+      LLL+  V+ AA   
Sbjct: 216 LPSAKPARAPRPAPRAREEAAAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLA 275

Query: 54  RSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVS 113
           RSP P + R       G A   R AA   G+++ +L P     R R + +     LPL  
Sbjct: 276 RSPPPLQPRL------GSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPR 329

Query: 114 RLGHAGE-------RGSPG---AGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS- 162
            L   GE       RG       G     +  SPP    P         PG+    R + 
Sbjct: 330 SLSRGGEVVGARRRRGGEERRVRGRRQGCALGSPPIPAGPA-------APGRAGERRAAR 382

Query: 163 -----PGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRA 212
                 GG    P   A+G G+  G++PR    RG  +  R   A+  G A  RA
Sbjct: 383 QWRKRGGGPGVSPREGAQGEGVRGGVTPR---ARGSSTCLRPSPATWQGGAPYRA 434



 Score = 38.5 bits (88), Expect = 0.013
 Identities = 73/291 (25%), Positives = 102/291 (35%), Gaps = 50/291 (17%)

Query: 91  PRRGGLRSRTDPAFGAGPLPLVSRLGHAGERGSPGAGDVNPVSASSPPGRPDPLLLTTFV 150
           PR  G+   +      GP PLV          +  AG++     ++P     P L  +  
Sbjct: 51  PRARGVEVASGRTRWTGPQPLVDT------PPARRAGELCEAPQTAPGFHFQPFLSLSPH 104

Query: 151 FPPGKTSAPRPSPGGRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATR 210
              G++    P  G RRG+      G G +P   P+               A+R    + 
Sbjct: 105 QERGRSKPSPPVSGTRRGKTGQWKEGRGSHPTPEPQ-------------RLAARRWLHSP 151

Query: 211 RAPSRRRNFGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGV 270
           R P+      AP       P  G  P++                  R P +  PG   G 
Sbjct: 152 REPTPPGRLSAP-------PRHGPHPQSF-----------------RRPSAHPPGRGSGR 187

Query: 271 EPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGP 330
            P G   ++A     R S  +   GS A        PA      PAP +   AAA  RG 
Sbjct: 188 VPRGQPEQQAWE--QRSSHFLAPEGSVA-SLLPSAKPA--RAPRPAPRAREEAAAGSRGR 242

Query: 331 GGATEPGFVTLAFRSRLP-LLRSPGPEGTSDAARAPAPGLRDRDLRAAPPR 380
           GGA  P     A +  L  LL +      +  AR+P P L+ R   A+PPR
Sbjct: 243 GGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPP-LQPRLGSASPPR 292


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 72/293 (24%), Positives = 103/293 (35%), Gaps = 56/293 (19%)

Query: 53  QRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLV 112
           Q  P PG+ +  P QGD  +R  R+     G       P +GG + +  P     P    
Sbjct: 151 QGPPPPGKPQGPPPQGDNKSRSSRSPP---GKPQGP--PPQGGNQPQGPPPPPGKPQGPP 205

Query: 113 SRLGHAGE--------RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPP----GKTSAPR 160
            + G+  +        +G P  GD    SA SPPG+P          PP     +   P 
Sbjct: 206 PQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQG--------PPPQGGNQPQGPP 257

Query: 161 PSPGGRRG-RPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF 219
           P PG  +G  P G  +  G  P   P+   P+G   +R           + R+P  +   
Sbjct: 258 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR-----------SSRSPPGKPQG 306

Query: 220 GAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRER 279
             P+G  +     G  P     +G    G     N  +GP    PG   G  P G S+ R
Sbjct: 307 PPPQGGNQ---PQGPPPPPGKPQGPPPQGG----NKPQGPPP--PGKPQGPPPQGGSKSR 357

Query: 280 AGAG----------LSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLAR 322
           +                ++PQ P   +   P + Q  PA      P PP   R
Sbjct: 358 SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGR 410



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 82/361 (22%), Positives = 120/361 (33%), Gaps = 65/361 (18%)

Query: 53  QRSPTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLV 112
           Q  P PG+ +  P QGD          +  G       P +GG + +  P     P    
Sbjct: 90  QGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGP------PPQGGNQPQGPPPPPGKPQGPP 143

Query: 113 SRLGHAGE--------RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPP----GKTSAPR 160
            + G+  +        +G P  GD    S+ SPPG+P          PP     +   P 
Sbjct: 144 PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG--------PPPQGGNQPQGPP 195

Query: 161 PSPGGRRG-RPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNF 219
           P PG  +G  P G  +  G  P   P+   P+G   ++           + R+P  +   
Sbjct: 196 PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ-----------SARSPPGKPQG 244

Query: 220 GAPRGSRRLR-------------PDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGL 266
             P+G  + +             P  G  P+     G+      +  +  R  RS  PG 
Sbjct: 245 PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGK 303

Query: 267 AGGVEPPGWSRERAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAAR 326
             G  P G ++ + G       PQ P      +P   QG P     Q P P   +++ + 
Sbjct: 304 PQGPPPQGGNQPQ-GPPPPPGKPQGPPPQGGNKP---QGPPPPGKPQGPPPQGGSKSRSA 359

Query: 327 RRGPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQR 386
           R  PG    P           P    P   G     +AP  G         PPRP    R
Sbjct: 360 RSPPGKPQGPP----QQEGNNPQGPPPPAGGNPQQPQAPPAGQPQ-----GPPRPPQGGR 410

Query: 387 P 387
           P
Sbjct: 411 P 411



 Score = 42.4 bits (98), Expect = 9e-04
 Identities = 54/222 (24%), Positives = 79/222 (35%), Gaps = 19/222 (8%)

Query: 121 RGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPP----GKTSAPRPSPGGRRG-RPLGAAR 175
           +G+P  G   P    SPPG+P          PP     +   P P PG  +G  P G  +
Sbjct: 37  QGAPPQGGNKPQGPPSPPGKPQG--------PPPQGGNQPQGPPPPPGKPQGPPPQGGNK 88

Query: 176 GTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAPRGS-RRLRPDAGK 234
             G  P   P+   P+G +S        +      +  ++ +    P G  +   P  G 
Sbjct: 89  PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148

Query: 235 FPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERAGAGLSRDSPQVPRS 294
            P+     G+      +  N  R  RS  PG   G  P G ++ + G       PQ P  
Sbjct: 149 KPQGPPPPGKPQGPPPQGDNKSRSSRSP-PGKPQGPPPQGGNQPQ-GPPPPPGKPQGPPP 206

Query: 295 GSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEP 336
               +P   QG P     Q P P    ++ + R  PG    P
Sbjct: 207 QGGNKP---QGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGP 245



 Score = 32.7 bits (73), Expect = 0.71
 Identities = 31/116 (26%), Positives = 44/116 (37%), Gaps = 22/116 (18%)

Query: 56  PTPGRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGPLPLVSRL 115
           P PG+ +  P QG    +      +  G       P +GG +SR+  +    P     + 
Sbjct: 320 PPPGKPQGPPPQGGNKPQGPPPPGKPQGP------PPQGGSKSRSARSPPGKPQGPPQQE 373

Query: 116 GHAGERGSPGAGDVNPVSASSPP-GRPDPLLLTTFVFPPGKTSAPRPSPGGRRGRP 170
           G+  +   P AG  NP    +PP G+P                 PRP  GGR  RP
Sbjct: 374 GNNPQGPPPPAGG-NPQQPQAPPAGQPQ--------------GPPRPPQGGRPSRP 414


>gi|40807477 retinoic acid induced 1 [Homo sapiens]
          Length = 1906

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 107/418 (25%), Positives = 151/418 (36%), Gaps = 67/418 (16%)

Query: 18   TLSEARPG----DWERRAGSSLCGSAEALLLSPHVTGA-----AQRSPTP-GRA------ 61
            +LS  +PG    D ER  G S    A +L   P+         A++ P P G++      
Sbjct: 945  SLSHMKPGEEGPDGERAPGDSTTSDA-SLAQKPNKPAVPEAPIAKKEPVPRGKSLRSRRV 1003

Query: 62   -RAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLRSRTDPAFGAGP-LPLVSRLGHAG 119
             R  P+  D   R      + L  +S T GP +G +     P  GA   LP +       
Sbjct: 1004 HRGLPEAEDSPCRAPVLPKDLLLPESCT-GPPQGQMEGAGAPGRGASEGLPRMC------ 1056

Query: 120  ERGSPGAGDVNPVSASSPPGRPDPLLLTTFVFPPGKTSAPRPS---PGGRRGRPLGAARG 176
                        ++A S P  P P  LTT   PP K    + +    G R G+P   A  
Sbjct: 1057 ---------TRSLTALSEPRTPGPPGLTTTPAPPDKLGGKQRAAFKSGKRVGKPSPKAAS 1107

Query: 177  TGLNPGLSPRLQE--PRGHQSARRTDTASRAGWATRRAPSRRRNFGAP-RGSRRLRPDAG 233
            +  NP   P   +  P G ++ + TD+ S  G   R    R R        S+R RP  G
Sbjct: 1108 SPSNPAALPVASDSSPMGSKT-KETDSPSTPGKDQRSMILRSRTKTQEIFHSKRRRPSEG 1166

Query: 234  KFPEASGGKGQRAAGAERVLNNGRGPR----SRLPGLAGGV-EPPGWSRERAGAGLS-RD 287
            + P     K        ++L+N   P     S  P   G V +     +  AG+ LS R 
Sbjct: 1167 RLPNCRATK--------KLLDNSHLPATFKVSSSPQKEGRVSQRARVPKPGAGSKLSDRP 1218

Query: 288  SPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEP-GFVTLAFRSR 346
               + R  ++  P   +    VL  +S    S +  A+   G G    P G  TL  R  
Sbjct: 1219 LHALKRKSAFMAPVPTKKRNLVLRSRS----SSSSNASGNGGDGKEERPEGSPTLFKRMS 1274

Query: 347  LPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPRPRPSQRPVSGLFKVKFFVPQSGPG 404
             P    P       A + P P   D  L+ A      S+    G  K K   P+ G G
Sbjct: 1275 SPKKAKPTKGNGEPATKLPPPETPDACLKLA------SRAAFQGAMKTKVLPPRKGRG 1326


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,411,226
Number of Sequences: 37866
Number of extensions: 1711470
Number of successful extensions: 10224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 1159
Number of HSP's that attempted gapping in prelim test: 7391
Number of HSP's gapped (non-prelim): 3097
length of query: 460
length of database: 18,247,518
effective HSP length: 106
effective length of query: 354
effective length of database: 14,233,722
effective search space: 5038737588
effective search space used: 5038737588
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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