Guide to the Human Genome
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Search of human proteins with 98985808

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98985808 alpha 1 type XI collagen isoform C preproprotein
[Homo sapiens]
         (1767 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...  3801   0.0  
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...  3782   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...  3777   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]     2902   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...  2480   0.0  
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...  2444   0.0  
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...  2243   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]  2109   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...  1229   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...  1226   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]     1199   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]    1193   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                   1117   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]    1102   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   991   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   986   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   984   0.0  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              947   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         936   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    920   0.0  
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              913   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        906   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   902   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   902   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   902   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   902   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               871   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   830   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   830   0.0  
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       825   0.0  

>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 3801 bits (9857), Expect = 0.0
 Identities = 1767/1767 (100%), Positives = 1767/1767 (100%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFT 300
            PDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFT
Sbjct: 241  PDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFT 300

Query: 301  EEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNE 360
            EEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNE
Sbjct: 301  EEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNE 360

Query: 361  EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ 420
            EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ
Sbjct: 361  EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQ 420

Query: 421  GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAI 480
            GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAI
Sbjct: 421  GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAI 480

Query: 481  LQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKR 540
            LQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKR
Sbjct: 481  LQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKR 540

Query: 541  GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 600
            GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI
Sbjct: 541  GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 600

Query: 601  GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660
            GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ
Sbjct: 601  GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660

Query: 661  GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP 720
            GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP
Sbjct: 661  GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYP 720

Query: 721  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA 780
            GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA
Sbjct: 721  GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA 780

Query: 781  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR 840
            GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR
Sbjct: 781  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR 840

Query: 841  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 900
            GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP
Sbjct: 841  GQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPP 900

Query: 901  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960
            GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP
Sbjct: 901  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960

Query: 961  GAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1020
            GAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP
Sbjct: 961  GAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1020

Query: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1080
            GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA
Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1080

Query: 1081 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1140
            GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF
Sbjct: 1081 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1140

Query: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200
            GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ
Sbjct: 1141 GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200

Query: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
            GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP
Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260

Query: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
            GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP
Sbjct: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380
            GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ
Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380

Query: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
            GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ
Sbjct: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440

Query: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500
            GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP
Sbjct: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500

Query: 1501 GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT 1560
            GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT
Sbjct: 1501 GEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGT 1560

Query: 1561 QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR 1620
            QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR
Sbjct: 1561 QTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR 1620

Query: 1621 ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA 1680
            ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA
Sbjct: 1621 ISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAA 1680

Query: 1681 WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVP 1740
            WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVP
Sbjct: 1681 WYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVP 1740

Query: 1741 IVDVMINDFGDQNQKFGFEVGPVCFLG 1767
            IVDVMINDFGDQNQKFGFEVGPVCFLG
Sbjct: 1741 IVDVMINDFGDQNQKFGFEVGPVCFLG 1767


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 3782 bits (9807), Expect = 0.0
 Identities = 1767/1806 (97%), Positives = 1767/1806 (97%), Gaps = 39/1806 (2%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDE---------------------------------------A 261
            PDCDSSAPKAAQAQEPQIDE                                       A
Sbjct: 241  PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEA 300

Query: 262  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 321
            NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY
Sbjct: 301  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 360

Query: 322  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 381
            ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG
Sbjct: 361  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 420

Query: 382  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 441
            AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP
Sbjct: 421  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 480

Query: 442  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 501
            GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP
Sbjct: 481  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 540

Query: 502  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 561
            GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR
Sbjct: 541  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 600

Query: 562  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 621
            GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP
Sbjct: 601  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 660

Query: 622  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681
            GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP
Sbjct: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720

Query: 682  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741
            GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK
Sbjct: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 742  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801
            GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP
Sbjct: 781  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840

Query: 802  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861
            GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP
Sbjct: 841  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900

Query: 862  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 921
            GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT
Sbjct: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960

Query: 922  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 981
            GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD
Sbjct: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041
            GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ
Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080

Query: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101
            GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK
Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140

Query: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161
            GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200

Query: 1162 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1221
            GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA
Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260

Query: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281
            GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP
Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320

Query: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1341
            GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380

Query: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1401
            GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP
Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440

Query: 1402 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1461
            GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP
Sbjct: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500

Query: 1462 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521
            GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG
Sbjct: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560

Query: 1522 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1581
            MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG
Sbjct: 1561 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1620

Query: 1582 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1641
            EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL
Sbjct: 1621 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1680

Query: 1642 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1701
            LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE
Sbjct: 1681 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1740

Query: 1702 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1761
            EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG
Sbjct: 1741 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1800

Query: 1762 PVCFLG 1767
            PVCFLG
Sbjct: 1801 PVCFLG 1806


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 3777 bits (9795), Expect = 0.0
 Identities = 1767/1818 (97%), Positives = 1767/1818 (97%), Gaps = 51/1818 (2%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDE---------------------------------------- 260
            PDCDSSAPKAAQAQEPQIDE                                        
Sbjct: 241  PDCDSSAPKAAQAQEPQIDEKKKSNFKKKMRTVATKSKEKSKKFTPPKSEKFSSKKKKSY 300

Query: 261  -----------ANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDY 309
                       ANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDY
Sbjct: 301  QASAKAKLGVKANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDY 360

Query: 310  DSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAE 369
            DSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAE
Sbjct: 361  DSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAE 420

Query: 370  TDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP 429
            TDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP
Sbjct: 421  TDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP 480

Query: 430  GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 489
            GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR
Sbjct: 481  GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 540

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
            GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR
Sbjct: 541  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609
            GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660

Query: 610  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 669
            GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI
Sbjct: 661  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 720

Query: 670  GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729
            GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD
Sbjct: 721  GPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 780

Query: 730  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789
            GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS
Sbjct: 781  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 840

Query: 790  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 849
            GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR
Sbjct: 841  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 900

Query: 850  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 909
            GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP
Sbjct: 901  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 960

Query: 910  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 969
            GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK
Sbjct: 961  GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1020

Query: 970  GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1029
            GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA
Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1080

Query: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089
            GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK
Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140

Query: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149
            GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR
Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200

Query: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209
            GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV
Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260

Query: 1210 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1269
            GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP
Sbjct: 1261 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1320

Query: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329
            GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA
Sbjct: 1321 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1380

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1389
            GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD
Sbjct: 1381 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1440

Query: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1449
            GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG
Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG 1500

Query: 1450 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1509
            GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI
Sbjct: 1501 GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPI 1560

Query: 1510 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCK 1569
            LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCK
Sbjct: 1561 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCK 1620

Query: 1570 DLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKP 1629
            DLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKP
Sbjct: 1621 DLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKP 1680

Query: 1630 GSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSY 1689
            GSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSY
Sbjct: 1681 GSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSY 1740

Query: 1690 DKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDF 1749
            DKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDF
Sbjct: 1741 DKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDF 1800

Query: 1750 GDQNQKFGFEVGPVCFLG 1767
            GDQNQKFGFEVGPVCFLG
Sbjct: 1801 GDQNQKFGFEVGPVCFLG 1818


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 2902 bits (7522), Expect = 0.0
 Identities = 1358/1839 (73%), Positives = 1489/1839 (80%), Gaps = 82/1839 (4%)

Query: 6    SRWKTKRWLWDFT--VTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGFCTN 63
            +RWK +  L      +  L L  L+     R A P D+LK LDFHN P+GI+KTTGFC  
Sbjct: 5    TRWKARSALRPGAPLLPPLLLLLLWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCAT 64

Query: 64   RKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHG 123
            R++SKG D AYRV+K AQLSAPTKQL+P   FPEDFSIL TVK KKG Q+FL+SIYNE G
Sbjct: 65   RRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQG 124

Query: 124  IQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCK 183
            IQQIG+E+GRSPVFL+EDHTGKP PEDYPLFR +N++DGKWHR+A+SV KK VT+I+DCK
Sbjct: 125  IQQIGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCK 184

Query: 184  KKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDC 243
            KKTTK LDRS+  ++D NGI VFGTRILDEEVFEGDIQQ L   D +AAYDYCEHYSPDC
Sbjct: 185  KKTTKFLDRSDHPMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEHYSPDC 244

Query: 244  DSSAPKAAQAQEPQIDEANIVDD------FQEYNY----------GTMESYQTEAPRHVS 287
            D++ P   Q+Q+P  DE     D      + EY Y           T      EA +  +
Sbjct: 245  DTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETT 304

Query: 288  GTNE---PNPVEE-----------------IFTEEYLTGEDYDSQRKNSEDTLYENKEID 327
               E   P P E                  I   +Y+  EDY +     + T  E +E  
Sbjct: 305  EVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENP 364

Query: 328  GRDSDLLVDGDL-------------------------GEY--------DFYEYKEYEDKP 354
             + +D     ++                         GE+        D   Y  Y D P
Sbjct: 365  DQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYD-P 423

Query: 355  TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM 414
            TS P+ E GPG+PA  D     I   G  GEKGQKGEPA++EPGML+EGPPGP GPAG+ 
Sbjct: 424  TSSPS-EIGPGMPANQDTIYEGIG--GPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP 480

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD---GSKGPTIS 471
            GPPG  GPTG  GDPG+RGPPGRPGLPGADGLPGPPGTMLMLPFR+GG    GSKGP +S
Sbjct: 481  GPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVS 540

Query: 472  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531
            AQE+QAQAILQQAR+ALRGP GPMGLTGRPGPVG PGS G KGE GD GPQGPRGVQGPP
Sbjct: 541  AQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPP 600

Query: 532  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 591
            GP GKPG+RGR G+DG RGMPG+ G KGDRGFDGL GLPG+KGHRG+ GP GPPGPPGDD
Sbjct: 601  GPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDD 660

Query: 592  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPP 651
            G RG+DGE+GPRGLPGE GPRGLLGP+G PG PG PG+ G+DG PGPKGN+GPQGEPGPP
Sbjct: 661  GERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPP 720

Query: 652  GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP 711
            GQQGNPG QGLPGPQG IGPPGEKGP GKPGL G+PGADGPPGHPGKEG  GEKG  GPP
Sbjct: 721  GQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPP 780

Query: 712  GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGED 771
            GPQGPIGYPGPRGVKGADG+RGLKG+KGEKGEDGFPGFKGDMG+KGDRGE+G  GPRGED
Sbjct: 781  GPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGED 840

Query: 772  GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831
            GPEGPKGR GP GDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGANGEKG R
Sbjct: 841  GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGR 900

Query: 832  GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891
            G  GKPGPRGQRGPTGPRG RG RG TGKPGPKG SGGDGP GPPGERGP GPQGP GFP
Sbjct: 901  GTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFP 960

Query: 892  GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP 951
            GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP GVVGPQGPTGETGP+GERGHPGPP
Sbjct: 961  GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPP 1020

Query: 952  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1011
            GPPGEQGLPG AGKEG KGDPGP G+ GKDGP GLRGFPG+RGLPG  GA GLKG EGP 
Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080

Query: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071
            GPPGP GSPGERG AG AGPIG+PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG+QGPV
Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140

Query: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131
            GLPGPAGP G PGEDGDKGEIGEPGQKGSKGDKGE GPPGP G QGP+G PG +G DGEP
Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191
            GPRGQQG+FGQKGDEG RGFPGPPGP+GLQGLPGPPGEKGE GDVG MGPPGPPGPRGP 
Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS 1260

Query: 1192 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251
            G  GADGPQGPPG +G+ G VGEKGEPGEAG PG PGE G  GPKGERGEKGE+GP GAA
Sbjct: 1261 GAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAA 1320

Query: 1252 GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPS 1311
            GPPG KGPPGDDGPKG+PGPVGFPGDPGPPGEPGPAGQDG  GDKG+DG+PGQ G PGP+
Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPT 1380

Query: 1312 GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371
            GE GP GPPGKRGPPG AG EGRQGEKGAKGEAG EGPPGKTGP+GPQG  GKPGP+GLR
Sbjct: 1381 GEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLR 1440

Query: 1372 GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEK 1431
            GIPGPVGEQGLPG+ G DGPPGPMGPPGLPGLKGD G KGEKGHPGLIGLIGPPGEQGEK
Sbjct: 1441 GIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 1432 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP 1491
            GDRGLPG QGS G KG+ GI GP+GP+GPPGPPGLPGP GPKG KGS+GP G KG++G P
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHP 1560

Query: 1492 GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADAD---DNILDYSDGMEEIFGSLNSLK 1548
            GPPG PGPPGEVIQPLPI +S +TRR+ +  Q   D   +N +DY+DGMEEIFGSLNSLK
Sbjct: 1561 GPPGPPGPPGEVIQPLPIQAS-RTRRNIDASQLLDDGNGENYVDYADGMEEIFGSLNSLK 1619

Query: 1549 QDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGET 1608
             +IE MK P+GTQ NPARTCKDLQL HPDFPDGEYW+DPNQGCS DSFKVYCNFT+GG T
Sbjct: 1620 LEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFTAGGST 1679

Query: 1609 CIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASAR 1668
            C++PDKKSEG RI+SWPKE PGSWFSEFKRGKLLSY+D EGN + +VQMTFL+LL+ASA 
Sbjct: 1680 CVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLLSASAH 1739

Query: 1669 QNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTV 1728
            QN TYHC+QS AW D ++GSYDKALRFLGSNDEEMSYDNNP+I+ L DGCA++KGY+KTV
Sbjct: 1740 QNVTYHCYQSVAWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALVDGCATKKGYQKTV 1799

Query: 1729 IEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1767
            +EI+TPK++QVPIVD+M NDFG+ +QKFGFEVGP CF+G
Sbjct: 1800 LEIDTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG 1838


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 2480 bits (6427), Expect = 0.0
 Identities = 1161/1756 (66%), Positives = 1353/1756 (77%), Gaps = 70/1756 (3%)

Query: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGT 274
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +        +   
Sbjct: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQ 259

Query: 275  MESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENK---EIDGRDS 331
             +  Q++    +    EP P  ++ T    T  DY       E+ + E+     ++   +
Sbjct: 260  NQEPQSQPTESLYYDYEP-PYYDVMTTG--TTPDYQDPTPGEEEEILESSLLPPLEEEQT 316

Query: 332  DLLVDGDLGEYDFYEYKEYEDKPTSPPNE-------------EFGPGVPAETDITETSIN 378
            DL V      +   EY E    P   P +             E GP + AET    +   
Sbjct: 317  DLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAET--AHSGAA 374

Query: 379  GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 438
             HG  G KG+KGEPAV+EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR 
Sbjct: 375  AHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA 434

Query: 439  GLPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL 497
            GLPG+DG PGPPGT LMLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG 
Sbjct: 435  GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 494

Query: 498  TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 557
            TGRPGP+G PGS G KGESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG 
Sbjct: 495  TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 554

Query: 558  KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 617
            KGDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP
Sbjct: 555  KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 614

Query: 618  RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677
            +G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGP
Sbjct: 615  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674

Query: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737
            QGKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG 
Sbjct: 675  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734

Query: 738  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797
            KGEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGK
Sbjct: 735  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794

Query: 798  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857
            LGVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG 
Sbjct: 795  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854

Query: 858  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917
            TGK G KGTSGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GF
Sbjct: 855  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 914

Query: 918  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977
            QGKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G 
Sbjct: 915  QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974

Query: 978  SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
             GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGR
Sbjct: 975  PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 1034

Query: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097
            PGPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQ
Sbjct: 1035 PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 1094

Query: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157
            KG+KG+KGE+GPPGPPG  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGP
Sbjct: 1095 KGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGP 1154

Query: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217
            IGLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGE
Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277
            PGE+G+PG  GE GV GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGD
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGD 1274

Query: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337
            PGPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG 
Sbjct: 1275 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1334

Query: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1397
            KGAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GP
Sbjct: 1335 KGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP 1394

Query: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP 1457
            PGLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP
Sbjct: 1395 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1454

Query: 1458 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRR 1517
            +GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR
Sbjct: 1455 IGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRR 1514

Query: 1518 HTEGMQADADDNILDYSD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDL 1571
              +G +   +D  +          G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL
Sbjct: 1515 SVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDL 1574

Query: 1572 QLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGS 1631
            +L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGETC+ P                   
Sbjct: 1575 KLCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD---------------- 1618

Query: 1632 WFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDK 1691
              ++F      SY+D EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D 
Sbjct: 1619 -VTQF------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDG 1662

Query: 1692 ALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGD 1751
             LR  G+N++E+S + +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G 
Sbjct: 1663 PLRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGA 1720

Query: 1752 QNQKFGFEVGPVCFLG 1767
              ++ G  +GPVCF+G
Sbjct: 1721 PPRRGGVLLGPVCFMG 1736


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 2444 bits (6333), Expect = 0.0
 Identities = 1152/1741 (66%), Positives = 1332/1741 (76%), Gaps = 126/1741 (7%)

Query: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGT 274
            VFEGD+Q+  I    +AAY+ CE    +C+       Q + PQ  + +      +     
Sbjct: 200  VFEGDVQELAIVPGVQAAYESCEQKELECE-----GGQRERPQNQQPHRAQRSPQQQPSR 254

Query: 275  MESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLL 334
            +   Q + P+    + +P P EE   EE L                         +S LL
Sbjct: 255  LHRPQNQEPQ----SQDPTPGEE---EEIL-------------------------ESSLL 282

Query: 335  VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 394
                                  PP EE   G               G  GE   KGEPAV
Sbjct: 283  ----------------------PPLEEAAHG-------------PRGLKGE---KGEPAV 304

Query: 395  VEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 454
            +EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR GLPG+DG PGPPGT L
Sbjct: 305  LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 364

Query: 455  MLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAK 513
            MLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G K
Sbjct: 365  MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 424

Query: 514  GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
            GESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+K
Sbjct: 425  GESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK 484

Query: 574  GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633
            GHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+D
Sbjct: 485  GHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 544

Query: 634  GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693
            GP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPP
Sbjct: 545  GPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 604

Query: 694  GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753
            GHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+
Sbjct: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 664

Query: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813
            G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPK
Sbjct: 665  GVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPK 724

Query: 814  GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873
            GS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP 
Sbjct: 725  GSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPH 784

Query: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933
            GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQ
Sbjct: 785  GPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQ 844

Query: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993
            G  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGER
Sbjct: 845  GAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGER 904

Query: 994  GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053
            GLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG P
Sbjct: 905  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964

Query: 1054 GEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113
            GEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPP
Sbjct: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024

Query: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGEN 1173
            G  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE 
Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084

Query: 1174 GDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233
            GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV 
Sbjct: 1085 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVK 1144

Query: 1234 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293
            GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  
Sbjct: 1145 GPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAK 1204

Query: 1294 GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353
            GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKT
Sbjct: 1205 GDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT 1264

Query: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413
            GPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEK
Sbjct: 1265 GPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEK 1324

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473
            GHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPK
Sbjct: 1325 GHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK 1384

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDY 1533
            G KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +  
Sbjct: 1385 GAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPT 1444

Query: 1534 S------DGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDP 1587
                    G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DP
Sbjct: 1445 GGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDP 1504

Query: 1588 NQGCSGDSFKVYCNFTSGGETCIYP-DKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLD 1646
            NQGC+ D+F+V+CNFT+GGETC+ P D  ++                         SY+D
Sbjct: 1505 NQGCARDAFRVFCNFTAGGETCVTPRDDVTQ------------------------FSYVD 1540

Query: 1647 VEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD 1706
             EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  LR  G+N++E+S +
Sbjct: 1541 SEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPE 1591

Query: 1707 NNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766
             +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+
Sbjct: 1592 TSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFM 1649

Query: 1767 G 1767
            G
Sbjct: 1650 G 1650


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 2243 bits (5813), Expect = 0.0
 Identities = 1025/1395 (73%), Positives = 1148/1395 (82%), Gaps = 41/1395 (2%)

Query: 380  HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 439
            HG  G KG+KGEPAV+EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR G
Sbjct: 269  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328

Query: 440  LPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 498
            LPG+DG PGPPGT LMLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG T
Sbjct: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388

Query: 499  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 558
            GRPGP+G PGS G KGESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG K
Sbjct: 389  GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448

Query: 559  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 618
            GDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+
Sbjct: 449  GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508

Query: 619  GTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 678
            G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQ
Sbjct: 509  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568

Query: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738
            GKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG K
Sbjct: 569  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628

Query: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798
            GEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKL
Sbjct: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 688

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 858
            GVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG T
Sbjct: 689  GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 748

Query: 859  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918
            GK G KGTSGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQ
Sbjct: 749  GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808

Query: 919  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978
            GKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  
Sbjct: 809  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868

Query: 979  GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038
            GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRP
Sbjct: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928

Query: 1039 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK 1098
            GPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQK
Sbjct: 929  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988

Query: 1099 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1158
            G+KG+KGE+GPPGPPG  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPI
Sbjct: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048

Query: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218
            GLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEP
Sbjct: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108

Query: 1219 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1278
            GE+G+PG  GE GV GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDP
Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168

Query: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1338
            GPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG K
Sbjct: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 1339 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1398
            GAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPP
Sbjct: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288

Query: 1399 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1458
            GLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+
Sbjct: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348

Query: 1459 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1518
            GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR 
Sbjct: 1349 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408

Query: 1519 TEGMQADADDNILDYSD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQ 1572
             +G +   +D  +          G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+
Sbjct: 1409 VDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLK 1468

Query: 1573 LSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSW 1632
            L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGETC+ P                    
Sbjct: 1469 LCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------- 1511

Query: 1633 FSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1692
             ++F      SY+D EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  
Sbjct: 1512 VTQF------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGP 1556

Query: 1693 LRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQ 1752
            LR  G+N++E+S + +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G  
Sbjct: 1557 LRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAP 1614

Query: 1753 NQKFGFEVGPVCFLG 1767
             ++ G  +GPVCF+G
Sbjct: 1615 PRRGGVLLGPVCFMG 1629



 Score = 1021 bits (2639), Expect = 0.0
 Identities = 606/1410 (42%), Positives = 734/1410 (52%), Gaps = 137/1410 (9%)

Query: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGT 274
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +        +   
Sbjct: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQ 259

Query: 275  MESYQTEA---PRHVSG-TNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRD 330
             +  Q++A   PR + G   EP  +E     E   G +           L     I G  
Sbjct: 260  NQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE-------GPAGLIGPPGIQGNP 312

Query: 331  SDLLVDGDLGEYDFYEYKEYEDKPTSPPNE-----EFGPG------------VPAETDIT 373
              +   G+ G          +  P  P         FG G              A+  + 
Sbjct: 313  GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372

Query: 374  ETSINGHGAYGEKGQKGEPAVV----EPGMLVE----GPPGPAGPAGIMGPP-------- 417
            +  +   G  G  G  G P  +     PG+  E    GP GP GP G+ GPP        
Sbjct: 373  QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432

Query: 418  -GLQGPTGPPGDP---GDRGPPGRPGLP---------GADGLPGPPGTMLMLPFRYGGDG 464
             G  G  G PGDP   GDRG  G PGLP         GA GLPGPPG         G DG
Sbjct: 433  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGE----DGERGDDG 488

Query: 465  SKGPTISAQEAQAQAILQQARIALRGP---PGPMGLTGRPGPVGGPGSSGAKGESGDPGP 521
              GP     E+  + +L       +GP   PGP G+ G  GP G  GS G +GE G PG 
Sbjct: 489  EIGPRGLPGESGPRGLL-----GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQ 543

Query: 522  QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581
            QG  G QG PGP G  G  G  G  G  G+PG PG+ G  G  G  G PG KG++G  GP
Sbjct: 544  QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 603

Query: 582  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGP------RGLLGPRGTPGAPGQPGMAGVDGP 635
            QGP G PG  G++G DG  G +G  GE G       +G +G +G  G  G PG  G DGP
Sbjct: 604  QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGP 663

Query: 636  PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695
             GPKG  GP G+PGPPG  G  G  G+PG  G  G  G KG  G PG  G  G  G  G 
Sbjct: 664  EGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 696  PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK------GEDGFPGF 749
             GK G  GE+G  GP G +GP G  G  G KG  G  G  G  GE+      G +GFPG 
Sbjct: 724  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783

Query: 750  KGDM------GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGL 803
            KG        GL G  G+ G++G +G+ GP GP G  GP G  G +G  GE+G  G PG 
Sbjct: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843

Query: 804  P---GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 860
            P   G PG  G +G+ G PG PGA G+ G  G+ G PG RG  G  G  G +G  GP+G 
Sbjct: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903

Query: 861  PGP------KGTSGGDGPPGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQ 911
            PGP      +G +G  GP GPPG  GPQGP G     G PG KGP GP G+DG+ G  G 
Sbjct: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963

Query: 912  RGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 971
             G  G  G  G  G  G VG  G  G  G  GE G PGPPGP G  G PGAAG +G  G 
Sbjct: 964  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1023

Query: 972  PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
             GPQG  G  G  G RGF G  G  G QG PG  G +G  G  GP+G PG  G  G AGP
Sbjct: 1024 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP 1083

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091
                G  GPQGPPG  G  G PGEKG  G +G  G+QG  G+ GP G  G  GE G  GE
Sbjct: 1084 ---NGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGE 1140

Query: 1092 IGEPGQKGSKGDKGENGPPGP---PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148
             G PG KG  GD G  G PGP   PG  GP G  G  G DG  G RG+ G  GQ G  G 
Sbjct: 1141 PGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGP 1200

Query: 1149 RGFPGPPGPIGLQGLPGPPGE------KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  GPPGP+G +G  G PG       KG  GD G +G PG  GP GP GP G  GP G 
Sbjct: 1201 TGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGL 1260

Query: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262
             G  GSVG  G  G  G+AG PGP G  G+ G +G+ G KGE G PG  G  G  G  G+
Sbjct: 1261 RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320

Query: 1263 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGK 1322
             G +G PGP G PG  G  G PG +G  G G      G PG PGP GP G  G  GP G 
Sbjct: 1321 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPG------GPPGLPGPAGPKGAKGATGPGGP 1374

Query: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1352
            +            GEKG +G  G  GPPG+
Sbjct: 1375 K------------GEKGVQGPPGHPGPPGE 1392



 Score =  699 bits (1803), Expect = 0.0
 Identities = 417/920 (45%), Positives = 471/920 (51%), Gaps = 149/920 (16%)

Query: 726  KGADGVRGLKGSKGEKG-------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKG 778
            + A G RGLKG KGE          +G PG +G  GL G  G  G  GP G+ G  GP G
Sbjct: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 779  RA---GPTGDPGPSGQA-----------GEKGKL--------------------GVPGLP 804
            RA   G  G PGP G +           G+KG +                    G PG  
Sbjct: 326  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385

Query: 805  GYPGRQGPKGSTGFPGFPGANGE---KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861
            GY GR GP G  G PG  G +G+   +G RG  G  GP G+ G  G  G+ GARG  G P
Sbjct: 386  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445

Query: 862  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD------GLPGHPGQRGET 915
            G KG  G DG PG PGE+G +G  G  G PGP G  G  G D      GLPG  G RG  
Sbjct: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505

Query: 916  GFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972
            G +G  G PGP GV    GPQGP G  GP GE G PG  G PG QGLPG  G  G  G+ 
Sbjct: 506  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565

Query: 973  GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032
            GPQ   GK G  G+ G  G  G PG +G PG KG +GP GP GP+G PG RG  G  G  
Sbjct: 566  GPQ---GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR 622

Query: 1033 GL------------PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1080
            GL            PG  G  G  G  GE G PG +G  GP G  G  GP G PGP G  
Sbjct: 623  GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682

Query: 1081 GS------------PGEDGDKGEIGEPGQKGSKGDK------------GENGPPGPPGLQ 1116
            G             PG  G KG +G PG  G+ G+K            GE GP GP G +
Sbjct: 683  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742

Query: 1117 GP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170
            GP       GA G +GGDG  GP G++G+ G +G  G  G  GPPGP G  GLPG PG++
Sbjct: 743  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802

Query: 1171 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA------GNP 1224
            GE G  G  GPPGPPG  GPQG  G  GP G  G  G  G  GE+G PG A      G+P
Sbjct: 803  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP------ 1278
            GPPG  G  GP G RG  GE G PG AG PG K   G++GP G PGP G PG+       
Sbjct: 863  GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK---GNEGPSGPPGPAGSPGERGAAGSG 919

Query: 1279 ---GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335
               GPPG PGP G  G  G+KG  G+ G  GP G  G  GP G PG  GPPG AG +G +
Sbjct: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979

Query: 1336 GE---------KGAKGEAGAEGPPGKTGPV---------------GPQGPAGKPGPEGLR 1371
            GE         KG KGE G  GPPG  GPV               GPQG  G  G EG R
Sbjct: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039

Query: 1372 GI---PGPVGEQGLPGAAGQDGPP---GPMGPPGLPGLKGDP---GSKGEKGHPGLIGLI 1422
            G    PGP+G QGLPG +G+ G     GPMGPPG PG +G     G+ G +G PG +G +
Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099

Query: 1423 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482
            GPPGE+GE G+ G PG QG PG KG  G  G  G  G PG PG PGP+GP G+ G  G  
Sbjct: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159

Query: 1483 GQKGDSGLPGPPGSPGPPGE 1502
            G  G  G PGPPG  GP G+
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQ 1179



 Score =  240 bits (612), Expect = 1e-62
 Identities = 145/355 (40%), Positives = 165/355 (46%), Gaps = 86/355 (24%)

Query: 1227 PGEAGVGGPKGERGEKGE----------AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276
            P      GP+G +GEKGE           GPPG  GP G  GPP   G +GNPGPVG PG
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPP---GIQGNPGPVGDPG 319

Query: 1277 DPGPPGEPGPAGQDGV-----------------GGDKGED-------------------- 1299
            + GPPG  G  G DG                  GGDKG                      
Sbjct: 320  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 379

Query: 1300 ---------------GDPGQP------------GPPGPSGEAGPPGPPGKRGPPGAAGAE 1332
                           G PG P            GP GP G  GPPG  G+RG  GA GA 
Sbjct: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439

Query: 1333 GRQGEKGAKGEAGAEGPP------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386
            G  G+ G KG+ G +G P      G  G  G QG  G PG +G RG  G +G +GLPG +
Sbjct: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 1387 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446
            G  G  GP GPPG+P   G PG +G  G  G  G +GP GE G  G +G PGTQG PG +
Sbjct: 500  GPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556

Query: 1447 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
            G  G  G  GP G PG PG+PG  GP G+ G  GP G KG+ G  GP G  G PG
Sbjct: 557  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611



 Score = 36.2 bits (82), Expect = 0.29
 Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 13/56 (23%)

Query: 1464 PGLPGPQGPKGNKGS-------------TGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            P      GP+G KG               GP G +G +GL GPPG  G PG V  P
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP 318


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 2109 bits (5464), Expect = 0.0
 Identities = 1023/1748 (58%), Positives = 1213/1748 (69%), Gaps = 51/1748 (2%)

Query: 36   AAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTF 95
            A PVDVLKAL       G+ +  GFC  R  +   D A+R+ + + L  PT +LFP G F
Sbjct: 29   ADPVDVLKALGVQGGQAGVPEGPGFCPQR--TPEGDRAFRIGQASTLGIPTWELFPEGHF 86

Query: 96   PEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR 155
            PE+FS+L T++ +   QS LLSIY+E G +Q+G+ +G +   L     G P     PL +
Sbjct: 87   PENFSLLITLRGQPANQSVLLSIYDERGARQLGLALGPALGLL-----GDPFR---PLPQ 138

Query: 156  TVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEV 215
             VN+ DG+WHRVA+S++ + VT++ DC+ +   P+       +   G+TV GT+ L E+ 
Sbjct: 139  QVNLTDGRWHRVAVSIDGEMVTLVADCEAQP--PVLGHGPRFISIAGLTVLGTQDLGEKT 196

Query: 216  FEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQ--EPQIDEANIVDDFQEYNYG 273
            FEGDIQ+ LI+ DP+AA+  CE Y PDCD+ AP A  A   EP+          +    G
Sbjct: 197  FEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPRPRRKGKGKGRKKG 256

Query: 274  TMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRK--------------NSEDT 319
                 +         T+ P P     + E  T  D                     S  T
Sbjct: 257  RGRKGKGRKKNKEIWTSSPPPD----SAENQTSTDIPKTETPAPNLPPTPTPLVVTSTVT 312

Query: 320  LYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSING 379
               N  I  R  D     +LG  +    +E E+   S      GP   A    + T    
Sbjct: 313  TGLNATILERSLDPDSGTELGTLETKAAREDEEGDDST----MGPDFRAAEYPSRTQFQI 368

Query: 380  HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 439
                GEKG KGEPAV+E G   EGPPG  GP G++GP G  GP G PGDPG  GP G PG
Sbjct: 369  FPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPG 428

Query: 440  LPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG 499
            +PG DG+ GPPGT++M+PF++ G   KGP +S Q+AQAQA+LQQ +++++GPPGP+GLTG
Sbjct: 429  IPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG 488

Query: 500  RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 559
            RPGPVG PG  G KGE G  GPQGPRG+QGP GP G+ GK GRPGADG RG+PG+ G KG
Sbjct: 489  RPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKG 548

Query: 560  DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRG 619
            DRGFDGLPGLPG+KG RG+ G  G PGPPG+DG RG +G  GP G  GE GPRGLLGPRG
Sbjct: 549  DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRG 608

Query: 620  TPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQG 679
            +PG  G+PG+ G+DG PG KGN+GP GEPGPPGQQGN G QGLPGPQG IG PGEKGP G
Sbjct: 609  SPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPG 668

Query: 680  KPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKG 739
             PG+ GLPG+DGP GHPG EG +GEKGA GPPG  GP GYPGPRGVKG  G RGL+G KG
Sbjct: 669  NPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKG 728

Query: 740  EKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLG 799
            EKGEDGFPGFKGD+GLKGD+G+ G  GPRGEDGPEGPKG+AG  G+ GP G AGEKGKLG
Sbjct: 729  EKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLG 788

Query: 800  VPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859
            VPGLPGYPGR GPKGS GFPG  G  GEKG  G  G+PG  G+RGP G RG RG  G TG
Sbjct: 789  VPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATG 848

Query: 860  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919
            +PGPKG  G DG PG PGE+G  G QGP GFPGPKGPPG  GKDG PGHPGQRGE GFQG
Sbjct: 849  QPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQG 908

Query: 920  KTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979
            +TGPPGP GV+GPQG TGE GP+GERG PGPPGPPGEQGLPG  G+EGAKG+ GP G  G
Sbjct: 909  QTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLG 968

Query: 980  KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039
            K+GPAGLRGFPG +G PG  G  GLKG +GP GP G  GSPGERG  G AG IGLPG+ G
Sbjct: 969  KEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSG 1028

Query: 1040 PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKG 1099
             +GP GPAG+KG+ GE+GP GP G+DG+ GP+G  GP G AG  GE+GDKG++G PG KG
Sbjct: 1029 SEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKG 1088

Query: 1100 SKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG 1159
            SKGDKG+ GPPG PG++GP G PG  G DG  G RG  G+FGQKGD+G RGF G  GP G
Sbjct: 1089 SKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPG 1148

Query: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219
            LQGLPGPPGEKGE GDVG MGP G PGPRGPQGP G++G  G PG VG  G VGEKGE G
Sbjct: 1149 LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERG 1208

Query: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279
            +AG+PGPPG  G+ GPKG+ GEKG++GP GAAGPPG KGPPG+DG KG+ GP G PGD G
Sbjct: 1209 DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLG 1268

Query: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339
            PPG+PG +G DG  G+KG+ GD G PGPPG SGE G PGPPGKRGP G  G EGR+GEKG
Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG 1328

Query: 1340 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG 1399
            AKGE G +GPPG+TGP+G +GP G+ GPEGLRGIPGPVGE GL GA GQ GPPGP+GP G
Sbjct: 1329 AKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSG 1388

Query: 1400 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1459
            LPGLKGD G KGEKGH GLIGLIGPPGE GEKGD+GLPG QG PG KGD G PGP G LG
Sbjct: 1389 LPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLG 1448

Query: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1519
             PGPPG+ GP G KG+KGS G  G +GD+G  GPPG PG P E       L   + RR  
Sbjct: 1449 HPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE-------LHGLRRRRRF 1501

Query: 1520 EGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFP 1579
              +     +       G+EE+  SL SL  ++E ++ P GT   P   C +L  +HP  P
Sbjct: 1502 VPVPLPVVEG------GLEEVLASLTSLSLELEQLRRPPGTAERPGLVCHELHRNHPHLP 1555

Query: 1580 DGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRG 1639
            DGEYWIDPNQGC+ DSF+V+CNFT+GGETC+YPDKK E V+++SW KEKPG W+S F+RG
Sbjct: 1556 DGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKFEIVKLASWSKEKPGGWYSTFRRG 1615

Query: 1640 KLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSN 1699
            K  SY+D +G+ +N+VQ+ FLKLL+A+ARQNFTY C  +AAW D ++G Y  + RFLG+N
Sbjct: 1616 KKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQNAAAWLDEATGDYSHSARFLGTN 1675

Query: 1700 DEEMSYDNN--PFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFG 1757
             EE+S++      +    DGC  RKG  KT+ E ++ +   +P+ DV   DFG  NQKFG
Sbjct: 1676 GEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSSRAGFLPLWDVAATDFGQTNQKFG 1735

Query: 1758 FEVGPVCF 1765
            FE+GPVCF
Sbjct: 1736 FELGPVCF 1743


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 1229 bits (3179), Expect = 0.0
 Identities = 685/1442 (47%), Positives = 808/1442 (56%), Gaps = 65/1442 (4%)

Query: 358  PNEEFGPGVP-AETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416
            P   FG   P   TD+   S    G  G KGQKGEP  ++  +  +GPPGP GPAG  GP
Sbjct: 78   PEIPFGECCPICPTDLATAS----GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP 133

Query: 417  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
             G +G  G  G PG RG  G PG PG  G PGPPG     P   GG+ +        E  
Sbjct: 134  RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG--PPGLGGNFAAQMAGGFDEKA 191

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP 533
              A L      ++GP GPMG  G PGP G PG  G +G   E G+PG  GP G +GPPGP
Sbjct: 192  GGAQLG----VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP 247

Query: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 593
             GKPG  G  G  G  G  G PG +G RGF G PGLPG KGHRG  G  G  G  G  G+
Sbjct: 248  PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307

Query: 594  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 653
            +GE G  G  G PG  GPRGL G RG  G  G  G  G DG PGP G  GP G  G PG 
Sbjct: 308  KGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367

Query: 654  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 713
             G PG +G  GP G  GP G +GP+G+PG  G PG  G  G+PG +G  G KG+ G PG 
Sbjct: 368  PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 714  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 773
             G  G+PGPRG  G  G  G  G KG+ GE G  GFKG+ G KG   E G  GP+G  GP
Sbjct: 428  AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG---EPGPAGPQGAPGP 484

Query: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG---PKGSTGFPGFPGANGEKGA 830
             G +G+ G  G+PG  G  G  G+ G PG  G+PG+ G   PKG+ G  G  G  G KGA
Sbjct: 485  AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544

Query: 831  RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 890
             G  G+PG  G  G  G  G  G  GP GK GP G  G DG PGPPG +G +G  G +GF
Sbjct: 545  NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 891  PGPKGPPGPPGK---DGLPGHPGQRGETGFQGKTG---PPGPGGVVGPQGPTGETGPIGE 944
            PGPKG  G PGK    GLPG PG RG  G  G+TG   PPGP G  G +G  G  GP G 
Sbjct: 605  PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 945  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1004
            +G PGPPGPPGE       GK G +G PG  G  G  GP G RGFPGERG PGAQG  G 
Sbjct: 665  QGLPGPPGPPGE------GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718

Query: 1005 KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGP 1061
            +G  G  G  GP G+ G  G  G  GP GL G PG +G     GP G++G  GEKGP+G 
Sbjct: 719  RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778

Query: 1062 AGRD---GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1118
             G+D   G+ GP+G PGPAG  G  GE G  G  G  G +G+ G++GE GPPGP G  GP
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGD 1175
             GA      DG+PG +G+QG  GQKGD GA G  GP   PGP G  G+ GP G +G  G 
Sbjct: 839  PGA------DGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1235
             G  G PG  G  GP G NG  GP GPPG  G  G  G +G+ G  G  G PG  G  GP
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 1236 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP---GPVGFPGDPGPPGEPGPAGQDGV 1292
             GE+GE G+ GP GA GPPG +G  G  G  G P   G  GFPG PGP GEPG  G  G 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 1293 GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1352
             GD+G  G  G PG  GP+GE G  G PG  GPPG  GA G +G++G  G  GA G PG 
Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072

Query: 1353 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE 1412
             G  GP GP GK G  G  G  GP+G  G  GA G  GP GP G     G  G+PG +G 
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD---KGEAGEPGERGL 1129

Query: 1413 KGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP 1472
            KGH G  GL G PG  G  GD+G  G  G  G +G  G  GP+G  G  G PG  GP GP
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189

Query: 1473 KGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILD 1532
            +G  G TGPAG  G+ G PGPPG PGP  ++     +   +K     + M+AD     L 
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1249

Query: 1533 YSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCS 1592
              D   E+  +L SL   IE ++ P G++ NPARTC+DL+L HP++  G+YWIDPNQGC+
Sbjct: 1250 QHDA--EVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCT 1307

Query: 1593 GDSFKVYCNFTSGGETCIYPDKKSEGVR--ISSWPKEKPGSWFSEFKRGKL-LSYLD--V 1647
             D+ KV+CN  + GETC+YP+  +   +   SS  KEK   WF E   G    SY D  +
Sbjct: 1308 LDAMKVFCNMET-GETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNL 1366

Query: 1648 EGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD- 1706
              N+ N VQMTFL+LL+    QN TYHC  S A+ D ++G+  KAL   GSND E+  + 
Sbjct: 1367 APNTAN-VQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEG 1425

Query: 1707 NNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVC 1764
            N+ F  T L DGC    G + KTVIE  + K  ++PI+D+   D G   Q+FG ++GPVC
Sbjct: 1426 NSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVC 1485

Query: 1765 FL 1766
            FL
Sbjct: 1486 FL 1487



 Score =  709 bits (1831), Expect = 0.0
 Identities = 421/961 (43%), Positives = 472/961 (49%), Gaps = 163/961 (16%)

Query: 705  KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE-------------DGFPGFKG 751
            K  L P  P G      P  +  A G  G KG KGE G+              G  G +G
Sbjct: 73   KDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG 132

Query: 752  DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP----------------------- 788
              G +GD+GE G  GPRG DG  G  G  GP G PGP                       
Sbjct: 133  PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192

Query: 789  -------SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR---------- 831
                    G  G  G  G PG  G PG QG +G+ G PG PG +G  G R          
Sbjct: 193  GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG 252

Query: 832  --GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 889
              G AGKPG  G+RGP GP+G+RG  G  G PG KG  G  G  G  GE G  G +G  G
Sbjct: 253  DDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESG 312

Query: 890  FPGPKGPPGPPGKDGLPGHPGQ---RGETGFQGKTGPPGPGGVVGPQGPT---------- 936
             PG  G PGP G  GLPG  G+    G  G +G  G PGP G  GP GP           
Sbjct: 313  SPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG 372

Query: 937  --GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 994
              GE GP G RG  G  GP GE G PG+ G  GA G+PG  GI G  G AG  G  G  G
Sbjct: 373  AKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432

Query: 995  LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE----- 1049
             PG +G PG +G  GP GP G  G PG  G  G  GP G PG  GPQG PGPAGE     
Sbjct: 433  FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492

Query: 1050 -KGAPGEKGPQGP------------AGRDGVQGPVGLP---GPAGPAGSPGEDGDKGEIG 1093
             +G PG  GP GP             G+DG+ GP G P   GP+G AG  G +GD G  G
Sbjct: 493  ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 552

Query: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP---RGQQGMFGQKGDEGARG 1150
            EPG  G++G  G  G  GP G  GP GAPG  G  G PGP   RGQ G+ G  G +GA G
Sbjct: 553  EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612

Query: 1151 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG 1210
             PG  G  GL G PG  G  G++G+ G  GPPGP GP G +G  GA GP G  G  G  G
Sbjct: 613  EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 672

Query: 1211 GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA---AGPPGAKGPPGDDGPKG 1267
              GE G+PG+ G PG  G  G+ GP+GERG  GE G PGA    GP G  G PG DGPKG
Sbjct: 673  PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732

Query: 1268 NPGPVGFPGDPGPP---GEPGPAGQDGVGGDKGEDGDPGQPGP----------------- 1307
              GP G PG  GPP   G PG  G  G+ G KG+ GD G+ GP                 
Sbjct: 733  ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792

Query: 1308 ----------------------------PGPSGEAGPPGPPGKRGPPGA---AGAEGRQG 1336
                                        PG  GE GPPGP G  GPPGA    GA+G QG
Sbjct: 793  PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852

Query: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396
            E G KG+AGA GP G +G  GPQGP G  GP+G RG  GP G  G PGAAG+ GPPG  G
Sbjct: 853  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912

Query: 1397 PPGLP------------GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
             PG P            G +GD G  G  G PGL G  GPPGE+GE GD G  G +G PG
Sbjct: 913  NPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972

Query: 1445 AK---GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
             +   G  GI G  G  G  G PGLPGP G  G +G+ G +G +G  G  GPPG  GP G
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG 1032

Query: 1502 E 1502
            E
Sbjct: 1033 E 1033


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 1226 bits (3172), Expect = 0.0
 Identities = 677/1415 (47%), Positives = 799/1415 (56%), Gaps = 60/1415 (4%)

Query: 384  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA 443
            G KGQKGEP  ++  +  +GPPGP GPAG  GP G +G  G  G PG RG  G PG PG 
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 444  DGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP 503
             G PGPPG     P   GG+ +        E    A L      ++GP GPMG  G PGP
Sbjct: 92   PGPPGPPGPPG--PPGLGGNFAAQMAGGFDEKAGGAQLG----VMQGPMGPMGPRGPPGP 145

Query: 504  VGGPGSSGAKG---ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 560
             G PG  G +G   E G+PG  GP G +GPPGP GKPG  G  G  G  G  G PG +G 
Sbjct: 146  AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 205

Query: 561  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620
            RGF G PGLPG KGHRG  G  G  G  G  G++GE G  G  G PG  GPRGL G RG 
Sbjct: 206  RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265

Query: 621  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680
             G  G  G  G DG PGP G  GP G  G PG  G PG +G  GP G  GP G +GP+G+
Sbjct: 266  TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325

Query: 681  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740
            PG  G PG  G  G+PG +G  G KG+ G PG  G  G+PGPRG  G  G  G  G KG+
Sbjct: 326  PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385

Query: 741  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 800
             GE G  GFKG+ G KG   E G  GP+G  GP G +G+ G  G+PG  G  G  G+ G 
Sbjct: 386  TGEPGIAGFKGEQGPKG---EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 801  PGLPGYPGRQG---PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857
            PG  G+PG+ G   PKG+ G  G  G  G KGA G  G+PG  G  G  G  G  G  GP
Sbjct: 443  PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 858  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK---DGLPGHPGQRGE 914
             GK GP G  G DG PGPPG +G +G  G +GFPGPKG  G PGK    GLPG PG RG 
Sbjct: 503  QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 915  TGFQGKTG---PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 971
             G  G+TG   PPGP G  G +G  G  GP G +G PGPPGPPGE       GK G +G 
Sbjct: 563  PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE------GGKPGDQGV 616

Query: 972  PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
            PG  G  G  GP G RGFPGERG PGAQG  G +G  G  G  GP G+ G  G  G  GP
Sbjct: 617  PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676

Query: 1032 IGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRD---GVQGPVGLPGPAGPAGSPGE 1085
             GL G PG +G     GP G++G  GEKGP+G  G+D   G+ GP+G PGPAG  G  GE
Sbjct: 677  PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGE 736

Query: 1086 DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1145
             G  G  G  G +G+ G++GE GPPGP G  GP GA      DG+PG +G+QG  GQKGD
Sbjct: 737  VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA------DGQPGAKGEQGEAGQKGD 790

Query: 1146 EGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             GA G  GP   PGP G  G+ GP G +G  G  G  G PG  G  GP G NG  GP GP
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850

Query: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262
            PG  G  G  G +G+ G  G  G PG  G  GP GE+GE G+ GP GA GPPG +G  G 
Sbjct: 851  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910

Query: 1263 DGPKGNP---GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGP 1319
             G  G P   G  GFPG PGP GEPG  G  G  GD+G  G  G PG  GP+GE G  G 
Sbjct: 911  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970

Query: 1320 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379
            PG  GPPG  GA G +G++G  G  GA G PG  G  GP GP GK G  G  G  GP+G 
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 1380 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
             G  GA G  GP GP G     G  G+PG +G KGH G  GL G PG  G  GD+G  G 
Sbjct: 1031 SGPAGARGIQGPQGPRGD---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1499
             G  G +G  G  GP+G  G  G PG  GP GP+G  G TGPAG  G+ G PGPPG PGP
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147

Query: 1500 PGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMG 1559
              ++     +   +K     + M+AD     L   D   E+  +L SL   IE ++ P G
Sbjct: 1148 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA--EVDATLKSLNNQIESIRSPEG 1205

Query: 1560 TQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGV 1619
            ++ NPARTC+DL+L HP++  G+YWIDPNQGC+ D+ KV+CN  + GETC+YP+  +   
Sbjct: 1206 SRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETCVYPNPANVPK 1264

Query: 1620 R--ISSWPKEKPGSWFSEFKRGKL-LSYLD--VEGNSINMVQMTFLKLLTASARQNFTYH 1674
            +   SS  KEK   WF E   G    SY D  +  N+ N VQMTFL+LL+    QN TYH
Sbjct: 1265 KNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTAN-VQMTFLRLLSTEGSQNITYH 1323

Query: 1675 CHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD-NNPFIKT-LYDGCASRKG-YEKTVIEI 1731
            C  S A+ D ++G+  KAL   GSND E+  + N+ F  T L DGC    G + KTVIE 
Sbjct: 1324 CKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEY 1383

Query: 1732 NTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766
             + K  ++PI+D+   D G   Q+FG ++GPVCFL
Sbjct: 1384 RSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1418



 Score =  858 bits (2218), Expect = 0.0
 Identities = 501/1163 (43%), Positives = 580/1163 (49%), Gaps = 133/1163 (11%)

Query: 337  GDLGEYDFYEYKEYEDKPTSP--PNEEFGPGVPAETDITET-SINGHGAYGEKGQKGEPA 393
            GD GE      +  + +P +P  P     PG P    +    +    G + EK    +  
Sbjct: 69   GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 128

Query: 394  VVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------GDRGPPGRPGLPGADGLP 447
            V++  M   GP GP GPAG  GP G QG  G PG+P      G RGPPG PG PG DG  
Sbjct: 129  VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 448  GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 507
            G PG                                 +   RGPPGP G  G PG  G P
Sbjct: 189  GKPG---------------------------------KAGERGPPGPQGARGFPGTPGLP 215

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP 567
            G  G +G  G  G +G  G  G  G +G PG+ G PG  G RG+PGE G  G  G  G  
Sbjct: 216  GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 275

Query: 568  GLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQP 627
            G  G  G  G  GP GP G PG  G  G  GE GP    G  GP G  GPRG PG PG P
Sbjct: 276  GNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP---TGARGPEGAQGPRGEPGTPGSP 332

Query: 628  GMAGVDGPPGPKGNMGPQGEPGPP---GQQGNPGPQGLPGPQGPIGP------------- 671
            G AG  G PG  G  G +G  G P   G  G PGP+G PGPQG  GP             
Sbjct: 333  GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392

Query: 672  --PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 729
               GE+GP+G+PG AG  GA GP G  GK G  GE G +GP GP G  G PG RG  G D
Sbjct: 393  GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452

Query: 730  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR---GEDGPEGPKGRAGPTGDP 786
            G+ G KG+ GE+G  G  G KG  G  G  GE G  G R   G  G  GP+G+ GP+G P
Sbjct: 453  GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512

Query: 787  GPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA---RGVAGKPGPRGQR 843
            G  G+ G  G  G  G PG  G  GPKG+ G PG  G  G  GA   RG+ GK G  G  
Sbjct: 513  GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 572

Query: 844  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903
            GP GP G  G RG  G PGP G  G  GPPGPPGE G  G QG  G  G  G  GP G+ 
Sbjct: 573  GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632

Query: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963
            G PG  G  G  G QG  G PG  G  GP+G +G  GP G +G PG  G PGE+G  G A
Sbjct: 633  GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

Query: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSP 1020
            G +G +GD G +G  G  G  G RG  G  G PG  GA G KG  GP GP G     G+P
Sbjct: 693  GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 752

Query: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK------GPQGPAGRDGVQGPVGL- 1073
            GERG  G  GP G  G PG  G PG  GE+G  G+K      GPQGP+G  G QGP G+ 
Sbjct: 753  GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 812

Query: 1074 -----------------PGPAGPAGSPGEDGDKGEIGEP---GQKGSKGDKGENGPP--- 1110
                             PG AG  G PG +G+ G  G P   G+ G KG +G++GPP   
Sbjct: 813  GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRA 872

Query: 1111 GPPGLQGPVGAP---------GIAGGDGEPGPR---GQQGMFGQKGDEGARGFPGPPGPI 1158
            G PGLQGP G P         G +G +G PGP+   GQ+G+ G  G  G RGFPG PGP 
Sbjct: 873  GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932

Query: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE- 1217
            G  G  G PG  G+ G  GP+GPPG  GP G  G  G+ G  GPPG  G+ G  G++GE 
Sbjct: 933  GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGET 992

Query: 1218 -----PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272
                 PG  G PG PG AG  G +G+RGE G  GP G +GP GA+G  G  GP+G+ G  
Sbjct: 993  GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1052

Query: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332
            G PG+ G  G  G  G  G+ G  G  GD G  GP GPSG  GPPGP          G  
Sbjct: 1053 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP---------VGPS 1103

Query: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392
            G+ G  G  G  G  GP G++G  GP GP G PGP G  G PGP    G+  +A     P
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP----GIDMSAFAGLGP 1159

Query: 1393 GPMGPPGLPGLKGDPGSKGEKGH 1415
               GP  L  ++ D  + G + H
Sbjct: 1160 REKGPDPLQYMRADQAAGGLRQH 1182



 Score =  380 bits (977), Expect = e-105
 Identities = 218/502 (43%), Positives = 248/502 (49%), Gaps = 97/502 (19%)

Query: 1091 EIGEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146
            ++ +PG KG KG+ G+     GP GPPG QGP G  G  G  G+ G +G  G  G+ G+ 
Sbjct: 27   DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 1147 GARGFPGPPGPIGLQGLPGPPGEKGE---------------------NGDVGPMGPPGPP 1185
            G  G PGPPGP    G PGPPG  G                       G +GPMGP GPP
Sbjct: 87   GTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 1186 GPRGPQGPNGAD---------------GPQGPPGSVGSVGGVGEKGEPGEAGNPGP---- 1226
            GP G  GP G                 GP+GPPG  G  G  GE G+PG+AG  GP    
Sbjct: 144  GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 1227 -----PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281
                 PG  G+ G KG RG  G  G  G AG PG KG  G  G  G+PGP+G  G PG  
Sbjct: 204  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP------------GPPGKRGPPGAA 1329
            G  GPA   G  G +G DG PG  GPPGP G AG P            GP G RGP GA 
Sbjct: 264  GRTGPA---GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP------------- 1376
            G  G  G  G+ G AGA G PG  G  G +G AG PG  G  G PGP             
Sbjct: 321  GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 1377 -----VGEQGLPGAAGQDGP---PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ 1428
                  GE G+ G  G+ GP   PGP GP G PG  G+ G +G +G PG +G IGPPGE+
Sbjct: 381  GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 1429 GEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---------PGPPGLPGPQGPKGNKGST 1479
            G  G+RG PG  G  G KG  G  GP+G  GP         PG PGLPG +G  G  G  
Sbjct: 441  GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 1480 GPAGQKGDSGLPGPPGSPGPPG 1501
            GP G+ G SG PG  G PGPPG
Sbjct: 501  GPQGKVGPSGAPGEDGRPGPPG 522


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 1199 bits (3103), Expect = 0.0
 Identities = 670/1436 (46%), Positives = 785/1436 (54%), Gaps = 99/1436 (6%)

Query: 384  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP---PGRPGL 440
            G KGQKGEP +V     + G PGPAGP G  GP   +G  GP G PG RGP    G PG+
Sbjct: 110  GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP---RGERGPKGRPGPRGPQGIDGEPGV 166

Query: 441  PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA--------QAQAILQQARIALRGPP 492
            PG  G PGPPG     P   G DG   P  SAQ A         +Q  L    +   GP 
Sbjct: 167  PGQPGAPGPPGH----PSHPGPDGLSRP-FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR 221

Query: 493  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 552
            GP GL G+    GG G +G  GE GDPGP GP G +GP GP GKPG+ G PG +G  G  
Sbjct: 222  GPQGLQGQQ---GGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV 278

Query: 553  GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 612
            G  G+ G RGF G PGLPG KGHRG +G +GP G  G  G +GE G  GP G  G  GPR
Sbjct: 279  GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338

Query: 613  GL------LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQ 666
            G+      LGP+G PG  G  GM G  GP GP G  G  G PG PG +G  GP G  GP+
Sbjct: 339  GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPE 398

Query: 667  GPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVK 726
            GP G  GE GP G  G  GLPGA G  G PG +G +G  G  GPPG  GP G PGP+G  
Sbjct: 399  GPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458

Query: 727  GADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD---RGEVGQIGPRGEDGPEGPKGRAGPT 783
            G  G+R      G+ G+ G PGFKG+ G KG+    G  G IGP GE+G  GP+G  G  
Sbjct: 459  GPQGIR------GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512

Query: 784  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 843
            G PGP G+ G  G  G PG  G P   GPKG+ G  G  G++G KG++G  G+PG  G  
Sbjct: 513  GPPGPVGERGAPGNRGFPGSDGLP---GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP 569

Query: 844  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903
            G  G  G+ G +GP GK GP G  G DG PGPPG  G +G  G +G PGPKG  G PGK 
Sbjct: 570  GARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK- 628

Query: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963
                 PG+ G  G  G+ G PG  G VGP GP G  G  GERG  GPPGP G QGLPG  
Sbjct: 629  -----PGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 964  GKEGAKGDPGPQGISGKD------GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1017
            G  G  G PG QG+ G        GP G RG PGERG PG  G PG KG  G  GP GP 
Sbjct: 684  GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743

Query: 1018 GSPGERGSAGTAGPIGLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQ---GPV 1071
            GSPG  G+ G  GP GL G PG +   G PGP G++G  GEKG +G AG DG +   GP+
Sbjct: 744  GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPL 803

Query: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131
            G PGPAGP G  GE G +G +G PG +G+ G +GENGP G  G  GP G  G  G  GEP
Sbjct: 804  GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL------PGPPGEKGENGDVGPMGPPGPP 1185
            G  GQ+G  G  G +G  G PGP GP G+ GL       GPPG  G  G  G +GPPGP 
Sbjct: 864  GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 1186 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1245
            G  GP GP G  G +GPPG  G  G  G  G+ G AG PG PG+      KG+ GE G+ 
Sbjct: 924  GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD------KGDPGEDGQP 977

Query: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305
            GP G  GP G  G  G  G  G  G  G PG PGP G PG  G  G  GDKG  G  G P
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365
            G  GP GE GP GP G  G PG  GA G +G++G  G AG    PG  G  G  GP G P
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL---PGSQGAPGTPGPVGAP 1094

Query: 1366 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1425
            G  G RG PG  G  G PG AG+ G PGP GP G  G  GD G +G+KGH G  GL G P
Sbjct: 1095 GDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP 1154

Query: 1426 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK 1485
            G  G  G++   G+ G PG  G  G PGP GP G  G PG  GP GP G +GS G AG +
Sbjct: 1155 GPPGPNGEQ---GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE 1211

Query: 1486 GDSGLPGPPGSPGPPGEVIQPLPILSSKKTR-------RHTEGMQADADDNILDYSDGME 1538
            G  G PGPPG PGPPG +   L  +               TE   A  D N  D      
Sbjct: 1212 GPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTD-----P 1266

Query: 1539 EIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKV 1598
             +  +L SL   IE M+ P G++ +PARTC DL+L H     GEYWIDPNQG   D+ KV
Sbjct: 1267 GVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKV 1326

Query: 1599 YCNFTSGGETCIYPDKKSEGVRISSW-----PKEKPGSWFSEFKRGKLLSYLDVEGNSIN 1653
            YCN  + GETCI  +  S  V   +W     P  KP  +  +  RG   +Y D +  +  
Sbjct: 1327 YCNMET-GETCISANPSS--VPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTA 1383

Query: 1654 MVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIK- 1712
            + QMTFL+LL+  A QN TY C  S  + D  + +  KA+   G+ND ++  + N   + 
Sbjct: 1384 ITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRY 1443

Query: 1713 -TLYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766
              L D C+ R G   KTV E  T  + ++PI+D+   D G  +Q+FG E+GPVCF+
Sbjct: 1444 IVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV 1499



 Score =  690 bits (1781), Expect = 0.0
 Identities = 398/880 (45%), Positives = 450/880 (51%), Gaps = 98/880 (11%)

Query: 355  TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM 414
            T PP     PG+P        +I   G  G KG  G P          GPPG AGP G  
Sbjct: 407  TGPPGPVGSPGLPG-------AIGTDGTPGAKGPTGSPG-------TSGPPGSAGPPGSP 452

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQE 474
            GP G  GP G  G PGD G PG  G  G  G PGP G    +    G +G +GP      
Sbjct: 453  GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG-PPGEEGKRGP------ 505

Query: 475  AQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT 534
                    +      GPPGP+G  G PG  G PGS G  G  G  G +GP G  GP G  
Sbjct: 506  --------RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQ 557

Query: 535  GKPGKRGRPGADGGRGMPGEPGAKGDR---------GFDGLPGLPGDKGHRGERGPQGPP 585
            G PG+ G PG  G RG+ G PG +G           G DG PG PG  G RG+ G  G P
Sbjct: 558  GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLP 617

Query: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGL---LGPRGTPGAPGQPGMAGVDGPPGPKGNM 642
            GP G  G  G+ GE G  G+PG+ G  G    +GP G  G PG  G  G  GPPGP G  
Sbjct: 618  GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQ 677

Query: 643  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702
            G  G PGPPG+ G PG QG+PG  G +GP G +G +G PG  G PG  G P         
Sbjct: 678  GLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLP--------- 728

Query: 703  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD---MGLKGDR 759
            GEKG  G  GP GP G PGP G  G  G  GL+G  GE+G  G PG KGD   +G KG  
Sbjct: 729  GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788

Query: 760  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819
            G  G  G RG  GP GP G AGPTG+ G  G  G  G  G  G PG  G  GP G+ GF 
Sbjct: 789  GTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFA 848

Query: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGTSGGDGPPGP- 875
            G  G +G+ G +G  G+PG +G  G  GP+   GS G  GP G PG KG  G  GPPG  
Sbjct: 849  GPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT 908

Query: 876  --PGERGPQGPQGPVGFPGPKGPPGPPGKDGLP---GHPGQRGETGFQGKTGPP-GPG-- 927
              PG  G  GP GP G PGP GP G PGK+G P   G PG  G  G +G  GPP GPG  
Sbjct: 909  GFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDK 968

Query: 928  ------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 981
                  G  GP GP G  G  G+RG  G PG  GE+G+PG  G  G  G  GP G +G  
Sbjct: 969  GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL------P 1035
            GP G  G PG     G  G PG +G  G  G PG  G+ GERG  G  GP GL      P
Sbjct: 1029 GPPGPVGPPGSN---GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAP 1085

Query: 1036 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1095
            G PGP G PG AG++G PG +GP GP GR G +   GLPGP GP G  G+ GD+G+ G+ 
Sbjct: 1086 GTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKR---GLPGPQGPRGDKGDHGDRGDRGQK 1142

Query: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1155
            G +G  G +G  GPPGP G QG  G PG  G  G PGP          G  G  G PGP 
Sbjct: 1143 GHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP---------VGPSGKEGNPGPL 1193

Query: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1195
            GPI      GPPG +G  G+ GP GPPG PGP GP GP G
Sbjct: 1194 GPI------GPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  145 bits (367), Expect = 3e-34
 Identities = 99/242 (40%), Positives = 109/242 (45%), Gaps = 53/242 (21%)

Query: 354  PTSPPNE-----EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPA 408
            P  PP       E GP  PA  D T       GA GE+G +G+P          G PG  
Sbjct: 1033 PVGPPGSNGPVGEPGPEGPAGNDGTP---GRDGAVGERGDRGDPGPA-------GLPGSQ 1082

Query: 409  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD-GSKG 467
            G  G  GP G  G  G  GDPG RGP G PG  G  GLPGP G     P    GD G +G
Sbjct: 1083 GAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG-----PRGDKGDHGDRG 1137

Query: 468  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527
                                 RG  G  G TG  G  G PG +G +G +G PGP GPR  
Sbjct: 1138 D--------------------RGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPR-- 1175

Query: 528  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 587
             GPPGP G  GK G PG  G  G PG  G+ G+ G +G PG P         GP GPPGP
Sbjct: 1176 -GPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP---------GPPGPPGP 1225

Query: 588  PG 589
            PG
Sbjct: 1226 PG 1227


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 660/1394 (47%), Positives = 762/1394 (54%), Gaps = 71/1394 (5%)

Query: 406  GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 465
            G  GP G  GP G +GP GPPG  G  G PG PG PG  G PGPPG              
Sbjct: 109  GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL------------- 155

Query: 466  KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQ 522
             G   + Q +          I++ GP GP G  G PGP G PG  G +G   E G+PG  
Sbjct: 156  -GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGAS 214

Query: 523  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582
            GP G +GPPGP GK G  G  G  G  G  G PG +G RG  G  GLPG KGHRG  G  
Sbjct: 215  GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 583  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 642
            G  G  G  G +GE G  G  G PG+ GPRGL G RG PGAPG  G  G DG  G  G  
Sbjct: 275  GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 643  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 702
            GP G  GPPG  G  G +G  GPQGP G  G +G +G+PG  G  GA GP G+PG +GQ 
Sbjct: 335  GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 703  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 762
            G KGA G PG  G  G+PG RG  G  G  G  G KG  GE G PG KGD G KG+ G V
Sbjct: 395  GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454

Query: 763  G---QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819
            G     GP GE+G  G +G  GPTG PGP G+ G  G  G PG  G  G   PKG  G  
Sbjct: 455  GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG---PKGPAGER 511

Query: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879
            G PG  G KG+ G AG+PG  G  G  G  GS G+ GP GK GP G +G DG PGPPG  
Sbjct: 512  GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571

Query: 880  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 939
            G +G  G +GFPGPKG  G PGK       G+RG  G  G  GP G  G  G QGP G  
Sbjct: 572  GARGQAGVMGFPGPKGAAGEPGK------AGERGVPGPPGAVGPAGKDGEAGAQGPPGPA 625

Query: 940  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK------DGPAGLRGFPGER 993
            GP GERG  GP G PG QGLPG AG  G  G PG QG+ G        G  G RGFPGER
Sbjct: 626  GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685

Query: 994  GL---PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1050
            G+   PG  G  G  G  G  G  G  G+PG  GS G  G  G+PG  G  G PGP G++
Sbjct: 686  GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR 745

Query: 1051 GAPGEKGPQGPAGRDGVQG---PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN 1107
            G  G KG  G  G+DGV+G   P+G PGPAG  G  GE G  G  G  G +G+ GD+GE 
Sbjct: 746  GDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEP 805

Query: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1167
            GPPGP G  GP GA G  G  GEPG  G +   G  G  G  G  GPPGPIG  G PG  
Sbjct: 806  GPPGPAGFAGPPGADGQPGAKGEPGDAGAK---GDAGPPGPAGPAGPPGPIGNVGAPGAK 862

Query: 1168 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1227
            G +G  G  G  G PG  G  GP GP+G  GP GPPG  G  GG G +GE G AG PG  
Sbjct: 863  GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922

Query: 1228 GEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP---PGEP 1284
            G  G  GP GE+G       PGA GP GA G PG  G  G  G VG PG  G    PG P
Sbjct: 923  GPPGPPGPAGEKGS------PGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK--- 1341
            GP+G+ G  G  G  G+ G PGP GP G AGPPG  G+ G PGA G+ GR G  GAK   
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036

Query: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1401
            GE G  GPPG  G  G  GP G  G  G RG  GP G  G  G  G  GP GP GP G  
Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096

Query: 1402 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1461
            G  G+ G +G KGH G  GL GPPG  G  G++G  G  G  G +G    PG AG  G  
Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP---PGSAGAPGKD 1153

Query: 1462 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521
            G  GLPGP GP G +G TG AG  G  G PGPPG PGPP        +    + + H  G
Sbjct: 1154 GLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213

Query: 1522 MQADADD-NILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPD 1580
                ADD N++   D   E+  +L SL Q IE+++ P G++ NPARTC+DL++ H D+  
Sbjct: 1214 RYYRADDANVV--RDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKS 1271

Query: 1581 GEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR---ISSWPKEKPGSWFSE-F 1636
            GEYWIDPNQGC+ D+ KV+CN  + GETC+YP + S   +   IS  PK+K   WF E  
Sbjct: 1272 GEYWIDPNQGCNLDAIKVFCNMET-GETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESM 1330

Query: 1637 KRGKLLSYLDVEGNSINM-VQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRF 1695
              G    Y     +  ++ +Q+TFL+L++  A QN TYHC  S A+ D  +G+  KAL  
Sbjct: 1331 TDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLL 1390

Query: 1696 LGSNDEEMSYDNNP--FIKTLYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQ 1752
             GSN+ E+  + N         DGC S  G + KTVIE  T K  ++PI+DV   D G  
Sbjct: 1391 QGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAP 1450

Query: 1753 NQKFGFEVGPVCFL 1766
            +Q+FGF+VGPVCFL
Sbjct: 1451 DQEFGFDVGPVCFL 1464



 Score =  651 bits (1680), Expect = 0.0
 Identities = 383/853 (44%), Positives = 427/853 (50%), Gaps = 93/853 (10%)

Query: 358  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV----EPGMLVE-------GPPG 406
            P+   GPG P             G+ G+ G KGEP  V     PG   E       G PG
Sbjct: 417  PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476

Query: 407  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466
            P               TG PG PG+RG PG  G PGADG+ GP G         G  G  
Sbjct: 477  P---------------TGLPGPPGERGGPGSRGFPGADGVAGPKGP----AGERGSPGPA 517

Query: 467  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
            GP  S  EA              G PG  GL G  G  G PGS G  G++G PGP G  G
Sbjct: 518  GPKGSPGEA--------------GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563

Query: 527  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586
              GPPGP G  G+ G  G  G +G  GEPG  G+RG  G PG  G  G  GE G QGPPG
Sbjct: 564  RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623

Query: 587  PPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTPGAPGQ---------------PG 628
            P G  G RGE G  G    +GLPG AGP G  G  G  G PG                PG
Sbjct: 624  PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683

Query: 629  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAG 685
              GV GPPGP G  G  G PG  G +G+ G  G PG QG     G PGE+G  G PG  G
Sbjct: 684  ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 686  LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745
              G  GP G  G  G+ G +G  GP GP GP G PG +G  G  G  G  G++G  G+ G
Sbjct: 744  DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 746  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 805
             PG  G  G  G  G  GQ G +GE G  G KG AGP G  GP+G  G  G +G PG  G
Sbjct: 804  EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863

Query: 806  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865
              G  GP G+TGFPG  G  G  G  G AG PGP G  G  G +G RG  GP G+PG  G
Sbjct: 864  ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 866  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925
              G   PPGP GE+G  G  GP G PG  GP G  G+ G+ G PGQRGE GF G    PG
Sbjct: 924  PPG---PPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL---PG 977

Query: 926  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985
            P G  G QGP+G +   GERG PGP GPPG  G PG +G+EGA   PG +G  G+DG  G
Sbjct: 978  PSGEPGKQGPSGAS---GERGPPGPMGPPGLAGPPGESGREGA---PGAEGSPGRDGSPG 1031

Query: 986  LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1045
             +G  GE G  G  GAPG  G  GP GP G  G  GE G AG AGP+G  G  GP GP G
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 1046 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKG 1105
            P G+KG  GE+G +G  G  G     GL GP GP GSPGE          G  G+ G  G
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFS---GLQGPPGPPGSPGEQ---------GPSGASGPAG 1139

Query: 1106 ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP----IGLQ 1161
              GPPG  G  G  G  G+ G  G PGPRG+ G  G  G  G  G PGPPGP        
Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFS 1199

Query: 1162 GLPGPPGEKGENG 1174
             LP PP EK  +G
Sbjct: 1200 FLPQPPQEKAHDG 1212


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 1117 bits (2890), Expect = 0.0
 Identities = 648/1396 (46%), Positives = 753/1396 (53%), Gaps = 102/1396 (7%)

Query: 409  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG-SKG 467
            GPAG  GP G +GP GPPG  G+ GP G PG PG    PGPPG       +Y G G   G
Sbjct: 33   GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGP---PGPPGLGGNFAAQYDGKGVGLG 89

Query: 468  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 527
            P                 + L GP GP G  G PGP G  G +G  GE G  GP G RG 
Sbjct: 90   P---------------GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP 134

Query: 528  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 587
             GPPG  G+ G  G+PG  G RG+ G  GA   RGF G PGLPG KG RG  G  G  G 
Sbjct: 135  AGPPGKAGEDGHPGKPGRPGERGVVGPQGA---RGFPGTPGLPGFKGIRGHNGLDGLKGQ 191

Query: 588  PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 647
            PG  G++GE G  G  G PG+ G RGL G RG  GAPG  G  G DG  GP G  GP G 
Sbjct: 192  PGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS 251

Query: 648  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 707
             GPPG  G PGP+G  G  G  GP G  GP+G+ GL GL G  GPPG+PG  G +G KGA
Sbjct: 252  AGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGA 311

Query: 708  LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP 767
             G PG  G  G PGPRG+ G  G  G  G++G  GE G  G KG+ G KG+ G  G  GP
Sbjct: 312  AGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGP 371

Query: 768  ---RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
                GE+G  GP G AG  G PGP G  G  G  G+PG  G  G  GP GS G  G  G 
Sbjct: 372  PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431

Query: 825  NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 884
               +G  G AG+PG  G  GP G  GS G  GP GK GP G  G DG PGP G  G +G 
Sbjct: 432  ---RGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGE 488

Query: 885  QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 944
             G +GFPGPKGP G PGK+G  GH       G  G  G PGP G  G QGP G  G  G 
Sbjct: 489  PGNIGFPGPKGPTGDPGKNGDKGH------AGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542

Query: 945  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1004
            +G  GPPGPPG QGLPG +G  G  G PG +G+ G+ G  G  G  GERG PG  GA G 
Sbjct: 543  KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602

Query: 1005 KG---GEGPQGPPGPVGSPGERG------SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055
             G     GP GPPGP G+ GE G      +AG +GP GLPG  G  G PG  GEKG PG 
Sbjct: 603  TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL 662

Query: 1056 KGPQGPAGRDGVQGP---VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1112
            +G  G  GRDG +G    VG PGPAG  G  GE G  G  G  G +GS G++GE GP GP
Sbjct: 663  RGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGP 722

Query: 1113 PGLQGPVGA---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169
             G  GP GA   PG  G  G  GP+G+ G+ G  G  GA G  GP GP      PGP G 
Sbjct: 723  NGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP------PGPAGS 776

Query: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG------EAGN 1223
            +G+ G  G  G PG  G  GP GP+G  GP GPPG  G  G  G +G+ G      E G 
Sbjct: 777  RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836

Query: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283
             GPPG AG  GP GE G    AGPPG  GP G  G PG  G  G+ G  G PG  G  GE
Sbjct: 837  VGPPGFAGEKGPSGEAGT---AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGE 893

Query: 1284 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
            PGP G  G  G +G  G  G PG  G  GEAG  G PG  GPPG  G  G +GE+G  G 
Sbjct: 894  PGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGN 953

Query: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
             G  G  G  GP GP GPAGK G  G  G  GPV      G AG  GP GP GP G+ G 
Sbjct: 954  IGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPV------GPAGAVGPRGPSGPQGIRGD 1007

Query: 1404 KGDPGSKGEKGHPGL---IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1460
            KG+PG KG +G PGL    GL G PG  G  GD+G PG+ G  G +G  G  GPAG  G 
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067

Query: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTE 1520
             G PG  GP G +G +G  GPAG       PGPPG PGPPG        +S        +
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGP------PGPPGPPGPPG--------VSGGGYDFGYD 1113

Query: 1521 G--MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDF 1578
            G   +AD   +         E+  +L SL   IE +  P G++ NPARTC+DL+LSHP++
Sbjct: 1114 GDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEW 1173

Query: 1579 PDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSW---PKEKPGSWFSE 1635
              G YWIDPNQGC+ D+ KVYC+F S GETCI    + E +   +W    K+K   W  E
Sbjct: 1174 SSGYYWIDPNQGCTMDAIKVYCDF-STGETCI--RAQPENIPAKNWYRSSKDKKHVWLGE 1230

Query: 1636 -FKRGKLLSYLDVEG--NSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1692
                G    Y +VEG  +     Q+ F++LL   A QN TYHC  S A+ D  +G+  KA
Sbjct: 1231 TINAGSQFEY-NVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKA 1289

Query: 1693 LRFLGSNDEEM-SYDNNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDF 1749
            +   GSND E+ +  N+ F  T L DGC+ +   + KT+IE  T K  ++P +D+   D 
Sbjct: 1290 VILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDI 1349

Query: 1750 GDQNQKFGFEVGPVCF 1765
            G  +Q+F  ++GPVCF
Sbjct: 1350 GGADQEFFVDIGPVCF 1365



 Score =  753 bits (1943), Expect = 0.0
 Identities = 470/1092 (43%), Positives = 532/1092 (48%), Gaps = 166/1092 (15%)

Query: 348  KEYEDKPTSPPNEEFGPGVP-------AETDITETSINGHGAYGEKGQKGEP-AVVEPGM 399
            ++ ED PT PP     PG P       A+ D     + G G  G  G +G P A   PG 
Sbjct: 52   RDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGL-GPGPMGLMGPRGPPGAAGAPGP 110

Query: 400  L-VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP------PGT 452
               +GP G  G  G  GP G +GP GPPG  G+ G PG+PG PG  G+ GP      PGT
Sbjct: 111  QGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGT 170

Query: 453  MLMLPFR-----YGGDGSKG----PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP 503
              +  F+      G DG KG    P +  +           +   RG PG  G  G PGP
Sbjct: 171  PGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGP 230

Query: 504  VGG------------------------PGSSGAKGE------SGDPGPQGPR------GV 527
             G                         PG+ G KGE      +G  GP GPR      G+
Sbjct: 231  AGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGL 290

Query: 528  QGPPGPTGKPGKR---------------GRPGADGGRGMPGEPGAKGDRGFDGLPGLP-- 570
             GP GP G PG                 G PG  G RG+PG  GA G  G  GL G P  
Sbjct: 291  SGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350

Query: 571  -------GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 623
                   G+KG  G  GPQGPPGP G++G RG +GE G  G PG  G RG  G RG PGA
Sbjct: 351  AGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGA 410

Query: 624  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 683
             G+   AGV GPPG +G  GP G  GP G  G PG  GL GP+G  G PG  GP GK G 
Sbjct: 411  DGR---AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGP 467

Query: 684  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV------------ 731
             GLPG DG PG  G  G  GE G +G PGP+GP G PG  G KG  G+            
Sbjct: 468  VGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGN 527

Query: 732  ---------RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ---------------IGP 767
                     +G++G KGE+G  G PGF+G  G  G  GEVG+                GP
Sbjct: 528  NGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP 587

Query: 768  RGEDGPEGPKGRAGPT---GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
            RGE GP G  G AGPT   G  GPSG  G  G  G PG+ G  G  GP G +G PG  GA
Sbjct: 588  RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647

Query: 825  NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 884
             G  G +G  G+PG RG+ G  G  G+RGA G  G PGP G +G  G  G  G  GP GP
Sbjct: 648  AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707

Query: 885  QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 944
            +G  G  G  GP GP G  G  G  GQ G  G +G  GP G  GVVGP GP G  GP G 
Sbjct: 708  RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP 767

Query: 945  RGHPGPP------GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 998
             G PGP       GPPG  G PGAAG+    G PGP GISG  GP G  G  G RG  G 
Sbjct: 768  NGPPGPAGSRGDGGPPGMTGFPGAAGR---TGPPGPSGISGPPGPPGPAGKEGLRGPRGD 824

Query: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1058
            QG  G  G  G  GPPG  G  G  G AGTAGP   PG PGPQG  G  G  G PG +G 
Sbjct: 825  QGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGP---PGTPGPQGLLGAPGILGLPGSRGE 881

Query: 1059 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1118
            +   G  GV G VG PGP G AG PG  G  G +G PG  G+ G+ G +G P        
Sbjct: 882  R---GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNP-------- 930

Query: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP 1178
             G  G  G DG+PG +G++G  G  G  GA G PGP GP+   G  G  G +GE G  GP
Sbjct: 931  -GNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPV---GPAGKHGNRGETGPSGP 986

Query: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1238
            +GP G  GPRGP GP G  G +G PG  G  G  G KG  G  G PG  G  G  G  G 
Sbjct: 987  VGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGS 1046

Query: 1239 RGEKGEAGPPGAAGP---------PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289
             G  G  GP G +GP         PG  GP G  GP+G+ GP    G PGPPG PGP G 
Sbjct: 1047 VGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPA---GPPGPPGPPGPPGV 1103

Query: 1290 DGVGGDKGEDGD 1301
             G G D G DGD
Sbjct: 1104 SGGGYDFGYDGD 1115



 Score =  477 bits (1227), Expect = e-134
 Identities = 279/626 (44%), Positives = 319/626 (50%), Gaps = 100/626 (15%)

Query: 957  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016
            Q L     ++G  GD GP+               GERG PG  G  G  G  GP GPPGP
Sbjct: 23   QSLQEETVRKGPAGDRGPR---------------GERGPPGPPGRDGEDGPTGPPGPPGP 67

Query: 1017 VGSPGERGSAGT----------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066
             G PG  G+              GP+GL    GP+GPPG AG  G  G +GP G  G  G
Sbjct: 68   PGPPGLGGNFAAQYDGKGVGLGPGPMGL---MGPRGPPGAAGAPGPQGFQGPAGEPGEPG 124

Query: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL------QGPVG 1120
              GP G  GPAGP G  GEDG  G+ G PG++G  G +G  G PG PGL      +G  G
Sbjct: 125  QTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNG 184

Query: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1180
              G+ G  G PG +G+ G  G+ G  G  G  G PG  G  G PGP G +G +G VGP+G
Sbjct: 185  LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG 244

Query: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1240
            P GP G  GP G  GA GP+G  G+VG+ G  G  G  GE G PG  G     GP G  G
Sbjct: 245  PAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPV---GPPGNPG 301

Query: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP---PGEPGPAGQDGVGGDKG 1297
              G  G  GAAG PG  G PG  GP+G PGPVG  G  G     GEPGPAG  G  G+KG
Sbjct: 302  ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361

Query: 1298 EDGDPGQPGPPGPSGE------------AGPPGPPGKRGPPGA---AGAEGRQGEKGAKG 1342
            E G  G  GPPGPSGE            AGPPGPPG RG PG+    GA+GR G  G  G
Sbjct: 362  EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 1343 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP------GPVGEQGLPGAAGQDGPPGPMG 1396
              GA GP G  GP G  G  G+PG  G RG+P      GP G++G  G  G DG PGP+G
Sbjct: 422  SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481

Query: 1397 P------------PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
            P            PG  G  GDPG  G+KGH GL G  G PG  G  G +G PG QG  G
Sbjct: 482  PAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQG 541

Query: 1445 AKGD---------GGIPGPAGPLGPPGPP---------GLPGPQGPKGNK---------G 1477
             KG+          G+PGP+GP G  G P         GLPGP GP+G +         G
Sbjct: 542  GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 1478 STGPAGQKGDSGLPGPPGSPGPPGEV 1503
             TGP G +G SG PGP G+ G PG V
Sbjct: 602  PTGPIGSRGPSGPPGPDGNKGEPGVV 627



 Score =  145 bits (366), Expect = 3e-34
 Identities = 98/279 (35%), Positives = 108/279 (38%), Gaps = 106/279 (37%)

Query: 1329 AGAEGRQGEKGAKGEAGAEGPPGKT------------GPVGPQGPAGKPGPEGL------ 1370
            A  +  Q E   KG AG  GP G+             GP GP GP G PGP GL      
Sbjct: 20   ATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAA 79

Query: 1371 -------------------------------RGIPGPVGEQGLPGAAGQDGPPGPMGPP- 1398
                                           +G  GP GE G PG  G  G  GP GPP 
Sbjct: 80   QYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG 139

Query: 1399 --------------------------GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432
                                      G PG  G PG KG +GH GL GL G PG  G KG
Sbjct: 140  KAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKG 199

Query: 1433 DRGLPGTQGSPGAKGDGGIP------------------------GPAGPLGPPGPPGLPG 1468
            + G PG  G+PG  G  G+P                        GPAGP+G  GPPG PG
Sbjct: 200  EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259

Query: 1469 PQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
              GPK      GN G  GPAG +G+ GLPG  G  GPPG
Sbjct: 260  APGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPG 298


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 1102 bits (2849), Expect = 0.0
 Identities = 635/1397 (45%), Positives = 739/1397 (52%), Gaps = 125/1397 (8%)

Query: 479  AILQQARIALRGPP---GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG--- 532
            A+  Q   A   PP   GP G  G PGP   PG  G  G+ G PG  G  G  GPPG   
Sbjct: 86   AVCPQPPTAPTRPPNGQGPQGPKGDPGP---PGIPGRNGDPGIPGQPGSPGSPGPPGICE 142

Query: 533  --PTGKP------------------GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572
              PTG                    G  G PG  G  G PG PG  G  G  G PG  G 
Sbjct: 143  SCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGP 202

Query: 573  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP---RGTPGAPGQPGM 629
             G  G+ GP GPPGPPG  G  G  G+ G  G PG  G RGL GP   +G  G PG PGM
Sbjct: 203  PGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262

Query: 630  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--- 686
             G  G  G  G  G  G PG  G+ G PG  G PGP GP G PGE+G  G PG AG    
Sbjct: 263  KGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322

Query: 687  ---------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737
                     PG  GPPG  G  G  G KG +GP G  G  G PG RG  G  G  G +G 
Sbjct: 323  DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382

Query: 738  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK------------GRAGPTGD 785
             G  G +G PG KG+MG  G  G  G +G RG  GP G              G+ G  G+
Sbjct: 383  PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442

Query: 786  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA---------RGVAGK 836
            PGP G+ GE G  GVPG  G  G+ G  G  G  G PGA GE+GA          G+ G+
Sbjct: 443  PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502

Query: 837  PGPRGQRGPTGPRGSRGARGPTGK------------PGPKGTSGGDGPPGPPGER----- 879
             GP G+RG  GP G RGA G  G+            PG  G  G DG PGPPG +     
Sbjct: 503  KGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562

Query: 880  -GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 938
             GP GP GP G PG  G PGP G DG PG  G+RG  G  G  GPPG  G  GPQGP G 
Sbjct: 563  PGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622

Query: 939  TGPIGERGHPGPPGPPGEQGLPGAA---GKEGAKGDPGPQGISGKDGPAGLR---GFPGE 992
            TGP G++G  GPPGP G QGLPG     G+ G  G+PGP+G +G  G  G +   G PGE
Sbjct: 623  TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682

Query: 993  RGLPGAQGAPGLKGGEGPQGP---PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
            RG PG  GAPGL+GG GP GP    G  G PG  G+AGT G  G+PG  G  G PGP G+
Sbjct: 683  RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109
            KG PG  G  G  G+DG +GP G  GP GPAG PG+ G+ G  G PG  G +G  GE G 
Sbjct: 743  KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169
             GPP   GP G PG  G +GEPG +G++G  G+KG+ G  G  GPPG  G  G PGP G 
Sbjct: 803  TGPP---GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
            KGE G  G  G  G PG RG  GP G++G  GPPG  GS    G+ G PG AGN G PG 
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS---PGKDGPPGPAGNTGAPGS 916

Query: 1230 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289
             GV GPKG+ G+ GE G PGA GPPGA GP G  G  G  G  G PG PGP G PGP G 
Sbjct: 917  PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 1290 DGVGGDKGEDGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGE---KGAKGE 1343
             G  G  G +G  G+ GPPGP    G AG  G PG+ G PG+ G  GR G    KG +GE
Sbjct: 977  KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE 1036

Query: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
             G+ G PG  G  GP GP G  G  G RG  GP G  G PG AG  G PGP GP G  G 
Sbjct: 1037 NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGE 1096

Query: 1404 KGDPGSKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1460
             G+ G+ G KGH   PG  G  G PG  G++G  G PG  G  G  G  G PG  G  G 
Sbjct: 1097 TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH 1156

Query: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP--PGEVIQPLPILSSKKTRRH 1518
            PGP G PGP+G +G +GS G  G  G  G PGPPG+PGP   G     +  +  +K    
Sbjct: 1157 PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK---- 1212

Query: 1519 TEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDF 1578
              G      D  +D+    +EI  SL S+   IE +  P G++ NPAR C+DL+  HP+ 
Sbjct: 1213 AGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPEL 1272

Query: 1579 PDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSW----PKEKPGSWFS 1634
              GEYW+DPNQGC  D+ KV+CN  + GETCI  +  +  V    W      EK   WF 
Sbjct: 1273 KSGEYWVDPNQGCKLDAIKVFCNMET-GETCISANPLN--VPRKHWWTDSSAEKKHVWFG 1329

Query: 1635 EFKRGKL-LSYLDVE-GNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1692
            E   G    SY + E    +  VQ+ FL+LL++ A QN TYHC  S A+ D +SG+  KA
Sbjct: 1330 ESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKA 1389

Query: 1693 LRFLGSNDEEMSYD-NNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDF 1749
            L+ +GSN+ E   + N+ F  T L DGC    G + KTV E  T K  ++PIVD+   D 
Sbjct: 1390 LKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDI 1449

Query: 1750 GDQNQKFGFEVGPVCFL 1766
            G  +Q+FG +VGPVCFL
Sbjct: 1450 GGPDQEFGVDVGPVCFL 1466



 Score =  934 bits (2415), Expect = 0.0
 Identities = 527/1136 (46%), Positives = 586/1136 (51%), Gaps = 96/1136 (8%)

Query: 404  PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 463
            P  P  P    GP G +G  GPPG PG  G PG PG PG+ G PGPPG     P    G 
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPT---GP 148

Query: 464  GSKGPTISAQEAQAQAIL-----QQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD 518
             +  P   + + ++   +             GPPGP G +G PG  G PG  G  GE G 
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 519  PGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG- 574
             GP GP G  G   P GP GK G+ GRPG  G RG+PG PG KG  G  G PG+ G +G 
Sbjct: 209  AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268

Query: 575  --HRGERGPQGPPGPPGDDGMRGEDGEIGPRG------------LPGEAGPRGLLGPRGT 620
                GE+G  G PG  G++G+ GE+G  GP G            LPG AG RG  G RG+
Sbjct: 269  DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328

Query: 621  ---PGAPGQPGMAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGPQGLPGPQGPIGPPG- 673
               PG PG PG AG  G PG KG +GP G PG    PGQ+G PGPQG  G QGP GPPG 
Sbjct: 329  DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388

Query: 674  --------EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725
                    E GP G PG  GL GA GPPG  G  G  G +G  G PG  G  G PGPRG 
Sbjct: 389  NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 726  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785
            +G  G+ G+ G+KGE G+DG PG  G  GL G  GE G  G RG  GP G  G  GP G+
Sbjct: 449  RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE 508

Query: 786  ------PGPSGQAGEKGKLGVPGLPGY---PGRQGPKGSTGFPGFPGANGEKGARGVAGK 836
                   GP G AGE G+ GVPG PG    PG  G  GS G PG PG+ GE G  G  G 
Sbjct: 509  RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP--- 893
             GPRGQ G  G  G +G  G  GK G +G  GG GP GPPG+ G  GPQGP G  GP   
Sbjct: 569  SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGD 628

Query: 894  ---KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950
                GPPGP G  GLPG  G  GE G  G+ GP G  G  G  G  G+ G  GERG PG 
Sbjct: 629  KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL--------------- 995
             G PG +G  G  G EG KG  GP G  G  G  GL+G PGERG                
Sbjct: 689  AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 996  PGAQGAPGLKGGEGPQGP---PGPVGSPGERGSAGT------AGPIGLPGRPGPQGPPGP 1046
            PGA G PG  G  GP GP   PGP G PG++G  G       AGP G PG  G  GPPGP
Sbjct: 749  PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 1047 AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1106
            AG  GAPG+ G  G  G  G  G  G  GP G AG P   G  G  G PG +G KG++G 
Sbjct: 809  AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP---GGSGPAGPPGPQGVKGERGS 865

Query: 1107 NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1166
             G PG  G  G  G PG  G +G PGP G  G  G+ G  G  G  G PG  G+ G  G 
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925

Query: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP-- 1224
             G+ GE G  G  GPPG PGP G  G  GA G  GPPG  G  G  G +G  GE+G P  
Sbjct: 926  AGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985

Query: 1225 -------GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277
                   GPPG  G+ G  G  GE G  G PG+ G PG  G PG  G +G  G  G PG 
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045

Query: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337
            PG PG PGP G  G  GD+GE G  G  G PGP+G  G PGP G RG  G  G  G  G 
Sbjct: 1046 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1397
            KG +G  G  G PG  GP G QG  G PGP G R   GPVG  G PG  G  G PGP+GP
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR---GPVGPSGPPGKDGTSGHPGPIGP 1162

Query: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-KGDRGLPGTQGSPGAKGDGGIP 1452
            PG  G +G+ GS+G  GHPG  G  GPPG  G   G  G     G  G K  G  P
Sbjct: 1163 PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218



 Score =  834 bits (2155), Expect = 0.0
 Identities = 494/1119 (44%), Positives = 553/1119 (49%), Gaps = 170/1119 (15%)

Query: 358  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLV---EGPPGPAGPAGIM 414
            P +   PG P    I E+   G   Y  +    +   V+ G+ V    G PGPAGP G  
Sbjct: 126  PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYD---VKSGVAVGGLAGYPGPAGPPGPP 182

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQE 474
            GPPG  G  G PG PG +GPPG PG  G  G PGPPG +          G  GP  + ++
Sbjct: 183  GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI----------GPSGP--AGKD 230

Query: 475  AQAQAILQQARIALRGPP---GPMGLTGRPGPVGG---PGSSGAKGESGDPGPQGPRGV- 527
             ++    +     L GPP   GP G+ G PG  G     G +G KGE+G PG +G  G+ 
Sbjct: 231  GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290

Query: 528  -----QGPPGPTGKPGKRGRPGA---------DGGR---------------GMPGEPGAK 558
                  GP GP G PG+RGRPG          DG R               G PG PGAK
Sbjct: 291  GENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 559  GDRGFDGLPGLPGDKGHRGERGP------QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 612
            G+ G  G PG  G  G RGE GP      QGPPGPPG +G  G  GE+GP G+PG  G  
Sbjct: 351  GEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLM 410

Query: 613  GLLGPRGTPGAPGQPGM------------------------AGVDGPPGPKGNMGPQGEP 648
            G  GP G  GA G PG+                        AG+ G PG KG  G  G P
Sbjct: 411  GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470

Query: 649  GPPGQQGNP---------------GPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693
            G PG  G P               GP G+PG +GP G  G  GP G  G AG PG DG P
Sbjct: 471  GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530

Query: 694  GHPGKEGQSGEKGA------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 747
            G PG  G  G  G        GPPG QG  G PGP G  G  G  G+ G  G KG DG P
Sbjct: 531  GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 748  GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP------TGDPGPSGQAGEKGKLGVP 801
            G  G+ G  G  G  G  G  GE GP+GP G  GP      TG PGP G  G  G  G P
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 802  GLPGYPGRQGPKGSTGFPGFP------GANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 855
            G  G PG  GPKG  G PG P      GA GE+G  G+AG PG RG  GP GP G +GA 
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710

Query: 856  GPTGKPGPKGT---------SGGDGPPGP---------------PGERGPQGPQGPVGFP 891
            GP G PG  GT          GG G PGP               PG+ GP+GP GP+G P
Sbjct: 711  GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 892  GPKGPPGPPGKDGLPGHP---GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 948
            GP G PG  G+ G PG P   G RG  G +G+TGPPGP G  G  G  GE G  GERG P
Sbjct: 771  GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 949  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008
            G  G  G  G+ G  G  G  G PGPQG+ G+ G     G PG  G PGA+G PG  G  
Sbjct: 831  GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP---GGPGAAGFPGARGLPGPPGSN 887

Query: 1009 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA---GEKGAPGEKGPQGP---- 1061
            G  GPPGP GSPG+ G  G AG  G PG PG  GP G A   GEKG+PG +GP G     
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 1062 --AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1119
              AG  G +G  G PG  GP GSPG  G KGE G+PG  G  G++G  GP G PGL G  
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1179
            G PG  G  G  G  G+ G  G KGD G  G PG PG  G  G PGP G  G++GD G  
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067

Query: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239
            GP GP G  GP G  GA GPQGP G  G  G  G  G  G  G PG PG  G  GP G++
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127

Query: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1299
            G  G  GP G  GP G  GPPG DG  G+PGP+         G PGP G  G  G +G  
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI---------GPPGPRGNRGERGSEGSP 1178

Query: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1338
            G PGQPGPPGP G  GP       G  GAA   G  GEK
Sbjct: 1179 GHPGQPGPPGPPGAPGP-----CCGGVGAAAIAGIGGEK 1212



 Score =  381 bits (978), Expect = e-105
 Identities = 239/593 (40%), Positives = 271/593 (45%), Gaps = 142/593 (23%)

Query: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102
            P  P GE  A   + P  P      QGP G  G  GP G PG +GD G  G+PG      
Sbjct: 77   PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS----- 131

Query: 1103 DKGENGP---PGPPGL--------------------------------------QGPVGA 1121
                      PGPPG+                                       GP G 
Sbjct: 132  -------PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP 184

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI------------------GLQGL 1163
            PG +G  G PG  G QG  G+ G  G  G PGPPG I                  G +GL
Sbjct: 185  PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244

Query: 1164 PGPPGEK------------------GENGDVGPMGPPGPPGPRGPQGPNGADGPQGP--- 1202
            PGPPG K                  G NG+ G  G PG  G  G  G NGA GP GP   
Sbjct: 245  PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304

Query: 1203 ---------PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1253
                     PG+ G+ G  G +G  G+ G PGPPG AG  G  G +GE G AG PG+ G 
Sbjct: 305  PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364

Query: 1254 P------------GAKGPPGDDGPKGNP------GPVGFPGDP---GPPGEPGPAGQDGV 1292
            P            GA+GPPG  G  G+P      GP G PG P   G  G PGPAG +G 
Sbjct: 365  PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424

Query: 1293 GGDKGEDGDP------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346
             G +G  G+P      G+PGP G  GEAG PG PG +G  G  G+ G  G  G  G AG 
Sbjct: 425  PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE 484

Query: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406
             G PG  GP GP G  G+ GP G RG PGP G +G  G  G+DG PG  G  G+PG  G 
Sbjct: 485  RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGG 544

Query: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP-------GPAGPLG 1459
            PGS G+ G PG  G  G PG  G  G RG PG  G PG KG+ G P       GP GP G
Sbjct: 545  PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP-G 603

Query: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP------PGSPGPPGEVIQP 1506
            P GPPG  G  GP+G  G TGP G KGD+G PGP      PG+ GPPGE  +P
Sbjct: 604  PQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656



 Score =  156 bits (395), Expect = 1e-37
 Identities = 105/286 (36%), Positives = 116/286 (40%), Gaps = 80/286 (27%)

Query: 1298 EDGDPGQPGPPGPSGEAG---PPGPPGKRGPPGAAGAE------------GRQGEKGAKG 1342
            +D +   P P  P GE     P  P     PP   G +            GR G+ G  G
Sbjct: 68   DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127

Query: 1343 EAGAEGPPGK-----------------------------------TGPVGPQGPAGKPGP 1367
            + G+ G PG                                     GP GP GP G PG 
Sbjct: 128  QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187

Query: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL---IGLIGP 1424
             G  G PG  G QG PG  GQ GP GP GPPG  G  G  G  GE G PG     GL GP
Sbjct: 188  SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGP 247

Query: 1425 P---------------------GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGP 1463
            P                     G  GEKG+ G PG +G  G  G+ G PGP GP G PG 
Sbjct: 248  PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE 307

Query: 1464 ---PGLPGPQGPKGNKGSTGPAGQKGDSGLPGP---PGSPGPPGEV 1503
               PGLPG  G +GN G+ G  GQ G  G PG    PGSPG  GEV
Sbjct: 308  RGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  991 bits (2562), Expect = 0.0
 Identities = 597/1300 (45%), Positives = 673/1300 (51%), Gaps = 211/1300 (16%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 441  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 496
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 497  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 546
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 547  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 602
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 651
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 652  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 698
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 699  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 748
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 749  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 795
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 796  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 852
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 853  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 891
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 892  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 946  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1003 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1114
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1115 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1166
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1167 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1209
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1210 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1258 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-------- 1306
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG        
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV--------GP 1358
             PG SG+ G  G PG  G PG  G +G  G  G  G  G  GPPG  GP         GP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1359 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL 1418
            QGP G+PGP G +G+PGP G  GLPG  G  G  G  G PGLPGL   PG KG++G PGL
Sbjct: 1257 QGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL---PGLKGDQGPPGL 1313

Query: 1419 IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP 1472
             G  G PG  G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G 
Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1373

Query: 1473 ----KGNKGSTGPAGQKGDSGLPGP------PGSPGPPGE 1502
                KG+ G  G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1374 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413



 Score =  919 bits (2376), Expect = 0.0
 Identities = 577/1313 (43%), Positives = 644/1313 (49%), Gaps = 227/1313 (17%)

Query: 354  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 402
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 403  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 444
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 445  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 498
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 499  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 546
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 547  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 597
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 598  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 622
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 623  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 670
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 671  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 722
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 723  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 773
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 825
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 880
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 881  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 937
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 998  AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1108
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1109 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1158
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1219 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1262
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1263 ---DGPKGNPGPVGFPGDPGP------PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
               +GPKGNPGP G PG PGP      PG  GP G  G GG KGE G+PGQPG PG    
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL--- 1301

Query: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI 1373
               PG  G +GPPG  G  GR G  G KG+ G  G PG  G  GP G  G  GPEG  G+
Sbjct: 1302 ---PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 1374 PGPVGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1429
             GP G  GLPG +GQ     G  GP G PG PGLKG PG +G +G PG      P G  G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG------PTGPPG 1412

Query: 1430 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482
            + G  GLPG  G+ G KGD G+PG  G  G  GPPG  G QGP G  G++  A
Sbjct: 1413 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 544
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 545  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 603
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 604  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 663
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 664  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 710
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 711  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 767  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 827  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 868
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 869  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 907
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 963
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 964  GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1018
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1062
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1063 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1115 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1172
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1173 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1232
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1233 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1289
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1290 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1326
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1383
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1431
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1432 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1487 DSGLPGPPGSPGPPGE 1502
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 625  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 678
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 789
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 790  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 845
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 896
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 897  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 942
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 943  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1000
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1001 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1031
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1092 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1120
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1121 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1165
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1166 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1205
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1248
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1300
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1301 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1358
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1359 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1413
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  399 bits (1024), Expect = e-110
 Identities = 259/620 (41%), Positives = 292/620 (47%), Gaps = 117/620 (18%)

Query: 357  PPNEEFGPGVP-AETDITETSING----HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 411
            PP E   PG+P A   I      G     GA G  G KGE  ++ P     GPPGP G  
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGPLGIP 913

Query: 412  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG---- 467
            G  G PGL+G  G  G PG  GP G  G  G  GLPGPPG M   P   G  G KG    
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD--PNLLGSKGEKGEPGL 971

Query: 468  ---PTISAQEAQ-------AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517
               P +S  +          Q  L   +  L GPPGP G  G PG  G  G  G KG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLS-GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 518  DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK--------GDRGFDGLPGL 569
            D G  GP+GV+GPPGP+G PG+ G PG  G +G  G+PG          G +G  GLPG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 570  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            PG+ G +G  G  G PG PG  G +G+ G  G  G PG  GP+G+ GP G PG PG+PG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 630  AG------VDGPPGPKGNMGPQGEPGPPGQQG--------NPGPQGLPGPQGPIGP---- 671
             G        GPPG KG  G  G PGP GQ+G        NPGP GLPG  G  G     
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 672  -----PGEKGPQGKPGLAGLPGADGPPGHPGK-----EGQSGEKGALGPPGPQGPIGY-- 719
                 PG  GP+G+PG  G PG  GPPG PG      EG  G  G  GPPG  GP G+  
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQG 1270

Query: 720  -PGPRGVKGADGVRGLKGSKGEKGEDGFPGF------------------------KGDMG 754
             PGP G  G  G  G+KG KG  G+ G PG                         KGD G
Sbjct: 1271 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG 1330

Query: 755  LKGDRGEVGQIGPRGEDGPEGPKGRAG------PTGDPGPSGQ-------AGEKGKLGVP 801
            L G  G  G  GP G  G  GP+G  G      P G PGPSGQ       AG  G  G P
Sbjct: 1331 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1390

Query: 802  GLPGYPGRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 849
            GL G PG QGP+G              G PGF GA G KG  G+ G+PG RG  GP GP 
Sbjct: 1391 GLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD 1450

Query: 850  GSRGARGPTGKPGPKGTSGG 869
            G    +GP G PG    + G
Sbjct: 1451 G---LQGPPGPPGTSSVAHG 1467



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1377
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1498 GPPGEVIQPLP 1508
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1445 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1489
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1490 LPGPPGSPGPPGEVIQPLP 1508
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  986 bits (2548), Expect = 0.0
 Identities = 593/1291 (45%), Positives = 670/1291 (51%), Gaps = 199/1291 (15%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 441  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 496
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 497  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 546
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 547  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 602
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 651
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 652  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 698
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 699  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 748
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 749  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 795
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 796  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 852
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 853  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 891
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 892  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 946  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1003 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1114
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1115 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1166
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1167 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1209
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1210 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1258 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-----PPG 1309
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG     PPG
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGP 1367
              G +G  G  G  G PG  G  G +GE G  G  G +GPPG  G  GP  +GP G PGP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1427
            +G  G PG  G +G PG  G  G  G  G PG PGL G PG KG++G PGL G  G PG 
Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1316

Query: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP----KGNKG 1477
             G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G     KG+ G
Sbjct: 1317 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAG 1376

Query: 1478 STGPAGQKGDSGLPGP------PGSPGPPGE 1502
              G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1407



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 544
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 545  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 603
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 604  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 663
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 664  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 710
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 711  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 767  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 827  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 868
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 869  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 907
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 963
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 964  GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1018
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1062
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1063 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1115 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1172
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1173 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1232
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1233 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1289
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1290 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1326
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1383
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1431
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1432 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1487 DSGLPGPPGSPGPPGE 1502
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  892 bits (2306), Expect = 0.0
 Identities = 559/1291 (43%), Positives = 624/1291 (48%), Gaps = 236/1291 (18%)

Query: 354  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 402
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 403  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 444
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 445  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 498
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 499  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 546
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 547  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 597
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 598  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 622
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 623  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 670
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 671  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 722
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 723  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 773
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 825
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 880
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 881  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 937
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 998  AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1108
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1109 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1158
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1219 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1262
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1263 ---DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGP 1319
               +GPKGNPGP G PG PG PG  GP G  G GG KGE G+PGQPG PG  G  G  GP
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1304

Query: 1320 PGKRGPPGAAGAEGRQGE------------KGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
            PG +G PG  G  G +G+            KG  G  G+ GP G+ G +GP GP G PGP
Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGP 1364

Query: 1368 EG-------------------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1408
             G                   L+G+PGP G QGLPG  G  G PG  G PG  G  G  G
Sbjct: 1365 SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKG 1424

Query: 1409 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
              G  G PG  GL GPPG  G +G  G PGT
Sbjct: 1425 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 625  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 678
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 789
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 790  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 845
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 896
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 897  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 942
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 943  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1000
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1001 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1031
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1092 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1120
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1121 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1165
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1166 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1205
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1248
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1300
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1301 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1358
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1359 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1413
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  553 bits (1424), Expect = e-157
 Identities = 336/797 (42%), Positives = 389/797 (48%), Gaps = 151/797 (18%)

Query: 364  PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPG----- 418
            PG+P +           G  G  G KGEP +  PG+ + GPPGP G  GI GPPG     
Sbjct: 683  PGLPGQP----------GLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 419  ----LQGPTGPPGDPGDRG--------PPGRPGLPGADG---------LPGPPGTMLMLP 457
                L+GP GPPG PG +G        PPG PGLPG  G          PGPPG     P
Sbjct: 731  GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----P 786

Query: 458  FRYGGDGSKGPTISAQEAQAQAILQQAR---IALRGPPGPMGLTGRPGPVGGPGSSGAKG 514
             R G DG  GP            +       I ++GPPGP G+   PGP+G PG  G  G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPG 843

Query: 515  ESGDPGP-----------QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE--------- 554
            E GDPGP           +G  G+ G PGP G PG  G PG  G  G PG          
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 555  ---------------PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-----GMR 594
                           PG KGD G  G PGLPG  G +G +G  G PGPPG       G +
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 595  GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG---PP 651
            GE GE G  G+PG +GP+G  G  G PG PG  G  G+ GPPGPKGN G  G+PG   PP
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 652  GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP 711
            G +G  G  G PGPQG  GPPG  G  G+PG  GLPG  G  G PG     G  G  GP 
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPK 1082

Query: 712  GPQGPIGYPGPRGVKGA---DGVRGLKGSKGEKGEDGFPGFKG---------------DM 753
            G  G  GYPG  G+KG+    G+ GL G+ G KG+ G PGF G               + 
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE------------------- 794
            GL G+ G VG  G  G+ GP G KG+ G  G PGP+GQ GE                   
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202

Query: 795  -KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKP--GPRGQRGPTGPRGS 851
             KG  G+PG+PG PG  GPKG  GF GFPG  G  G  G  G    GP+G  GP GP G 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 852  RGARGPTGKPG---------PKGTSGGDGPPGPPGERGPQGP---QGPVGFPGPKGPPGP 899
             G  GP G PG          KG  G  G PG PG +G QGP   QG  G PG  G  G 
Sbjct: 1263 PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1322

Query: 900  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER-------GHPGPPG 952
            PG  G+PG PG +G +G  G  GP G  G++GP GP G  GP G+        G PG PG
Sbjct: 1323 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1382

Query: 953  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012
             PG +GLPG  G +G  G  GP G  G++G  G  G  G +G PG  G PG +G +GP G
Sbjct: 1383 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1442

Query: 1013 PPGPVGSPGERGSAGTA 1029
            P G  G PG  G++  A
Sbjct: 1443 PDGLQGPPGPPGTSSVA 1459



 Score =  399 bits (1025), Expect = e-110
 Identities = 258/614 (42%), Positives = 291/614 (47%), Gaps = 111/614 (18%)

Query: 357  PPNEEFGPGVP-AETDITETSING----HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 411
            PP E   PG+P A   I      G     GA G  G KGE  ++ P     GPPGP G  
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGPLGIP 913

Query: 412  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG---- 467
            G  G PGL+G  G  G PG  GP G  G  G  GLPGPPG M   P   G  G KG    
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD--PNLLGSKGEKGEPGL 971

Query: 468  ---PTISAQEAQ-------AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517
               P +S  +          Q  L   +  L GPPGP G  G PG  G  G  G KG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLS-GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 518  DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK--------GDRGFDGLPGL 569
            D G  GP+GV+GPPGP+G PG+ G PG  G +G  G+PG          G +G  GLPG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 570  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            PG+ G +G  G  G PG PG  G +G+ G  G  G PG  GP+G+ GP G PG PG+PG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 630  AG------VDGPPGPKGNMGPQGEPGPPGQQG--------NPGPQGLPGPQGPIGP---- 671
             G        GPPG KG  G  G PGP GQ+G        NPGP GLPG  G  G     
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 672  -----PGEKGPQGKPGLAGLPGADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRG 724
                 PG  GP+G+PG  G PG  GPPG PG  G +  G KG  GP GP G  G PGP G
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG 1270

Query: 725  VKGADGVRGLKGSKGEKGEDGFPGF------------------------KGDMGLKGDRG 760
              G  G  G+KG KG  G+ G PG                         KGD GL G  G
Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1330

Query: 761  EVGQIGPRGEDGPEGPKGRAG------PTGDPGPSGQ-------AGEKGKLGVPGLPGYP 807
              G  GP G  G  GP+G  G      P G PGPSGQ       AG  G  G PGL G P
Sbjct: 1331 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1390

Query: 808  GRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 855
            G QGP+G              G PGF GA G KG  G+ G+PG RG  GP GP G    +
Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG---LQ 1447

Query: 856  GPTGKPGPKGTSGG 869
            GP G PG    + G
Sbjct: 1448 GPPGPPGTSSVAHG 1461



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1377
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1498 GPPGEVIQPLP 1508
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1445 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1489
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1490 LPGPPGSPGPPGEVIQPLP 1508
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  984 bits (2545), Expect = 0.0
 Identities = 595/1297 (45%), Positives = 673/1297 (51%), Gaps = 208/1297 (16%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 441  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 496
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 497  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 546
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 547  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 602
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 651
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 652  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 698
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 699  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 748
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 749  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 795
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 796  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 852
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 853  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 891
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 892  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 946  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1003 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1057
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1058 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1114
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1115 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1166
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1167 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1209
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1210 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1258 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-----PPG 1309
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG     PPG
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGP 1367
              G +G  G  G  G PG  G  G +GE G  G  G +GPPG  G  GP  +GP G PGP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1368 EG------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1421
            +G       +G+PGP G  GLPG  G  G  G  G PGLPGL   PG KG++G PGL G 
Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL---PGLKGDQGPPGLQGN 1313

Query: 1422 IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP--- 1472
             G PG  G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G    
Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1373

Query: 1473 -KGNKGSTGPAGQKGDSGLPGP------PGSPGPPGE 1502
             KG+ G  G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1410



 Score =  917 bits (2371), Expect = 0.0
 Identities = 576/1310 (43%), Positives = 644/1310 (49%), Gaps = 224/1310 (17%)

Query: 354  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 402
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 403  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 444
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 445  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 498
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 499  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 546
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 547  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 597
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 598  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 622
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 623  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 670
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 671  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 722
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 723  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 773
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 825
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 880
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 881  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 937
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 938  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 998  AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1108
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1109 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1158
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1218
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1219 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1262
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1263 ---DGPKGNPGPVGFPGDPGPPGEPGPAGQDGV---GGDKGEDGDPGQPGPPGPSGEAGP 1316
               +GPKGNPGP G PG PG  G PGP G  G+   GG KGE G+PGQPG PG       
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL------ 1298

Query: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376
            PG  G +GPPG  G  GR G  G KG+ G  G PG  G  GP G  G  GPEG  G+ GP
Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1358

Query: 1377 VGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432
             G  GLPG +GQ     G  GP G PG PGLKG PG +G +G PG      P G  G+ G
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG------PTGPPGDPG 1412

Query: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482
              GLPG  G+ G KGD G+PG  G  G  GPPG  G QGP G  G++  A
Sbjct: 1413 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 544
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 545  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 603
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 604  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 663
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 664  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 710
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 711  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 766
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 767  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 826
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 827  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 868
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 869  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 907
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 963
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 964  GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1018
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1062
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1063 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1115 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1172
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1173 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1232
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1233 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1289
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1290 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1326
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1383
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1431
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1432 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1486
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1487 DSGLPGPPGSPGPPGE 1502
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 625  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 678
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 789
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 790  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 845
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 896
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 897  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 942
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 943  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1000
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1001 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1031
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1092 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1120
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1121 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1165
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1166 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1205
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1248
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1300
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1301 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1358
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1359 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1413
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1473
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  401 bits (1030), Expect = e-111
 Identities = 246/565 (43%), Positives = 280/565 (49%), Gaps = 85/565 (15%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413
            PT     +  PG+P      + ++      G KG+KGEP +  PG  + G  GP G  G+
Sbjct: 936  PTGEKGSKGEPGLPGPPGPMDPNL-----LGSKGEKGEPGL--PG--IPGVSGPKGYQGL 986

Query: 414  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 473
             G PG  G +G PG PG  GP G PGLPG  GL GPPG    L    G  G  GP     
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG----LKGTIGDMGFPGPQ---- 1038

Query: 474  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD-----PGPQGPRGVQ 528
                          + GPPGP G+ G+PG  G PG  G KG+ G      PG  GP+G  
Sbjct: 1039 -------------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEP 1085

Query: 529  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG----- 583
            G PG  G PG +G  G  G  G+PG PGAKG  G  G PG PG  G +G  GP G     
Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145

Query: 584  -------------PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--LGPRGTPGAPGQPG 628
                          PGPPG+ G  G+DG  GP G  GE G  G    GP G PG  GQ G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205

Query: 629  MAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGPQGLPGP--QGPIGPPGEKGPQGKPGL 683
              G+ G PG  G  GP+GEPG    PG QG PGP G PGP  +GP G PG +GP G+PG 
Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGF 1265

Query: 684  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
             GLPG +GPPG PG  G  GEKG  G PG  G  G  G +G  G  G  G  G  G KG+
Sbjct: 1266 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1325

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-------AGEKG 796
             G PG  G  G+KG  G  G  GP GE G  GP G   P G PGPSGQ       AG  G
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG---PPGLPGPSGQSIIIKGDAGPPG 1382

Query: 797  KLGVPGLPGYPGRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRG 844
              G PGL G PG QGP+G              G PGF GA G KG  G+ G+PG RG  G
Sbjct: 1383 IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1442

Query: 845  PTGPRGSRGARGPTGKPGPKGTSGG 869
            P GP G    +GP G PG    + G
Sbjct: 1443 PPGPDG---LQGPPGPPGTSSVAHG 1464



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1377
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1498 GPPGEVIQPLP 1508
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1325 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1445 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1489
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1490 LPGPPGSPGPPGEVIQPLP 1508
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  947 bits (2448), Expect = 0.0
 Identities = 613/1598 (38%), Positives = 758/1598 (47%), Gaps = 226/1598 (14%)

Query: 355  TSP--PNEEFGPGVPAETDITETSINGHGAY--------GEKGQKGEPAVVEPGMLVEG- 403
            TSP  P++    G PA+T +    ++   A         G   +   PA  +P   +   
Sbjct: 303  TSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITAT 362

Query: 404  ------PPGPAGPAG----IMGPPGLQG-----------PTGPPGDPGDRGPPGRPGLPG 442
                  P  P+ P+     I  P   Q            PT     P  R  P R   P 
Sbjct: 363  KIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPA 422

Query: 443  ADGL---PG----PPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ---ARIALRGPP 492
               +   PG    PP +   LP          PT++  EA+  +   +   AR +   PP
Sbjct: 423  EKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPP 482

Query: 493  GPMGLTGRPGPVGG------PGSSGAKGESGDPGPQGPRGVQGP-PGPTG--KP-----G 538
                L+  P P  G      P ++     SG   P+    V  P   PTG  KP      
Sbjct: 483  PFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEAS 542

Query: 539  KRGRPGADGGRGMPGEPG-AKGDRGFDGLPGLPGDKG----------------------- 574
            K+  P +   + +P  PG A  D     L   P  +                        
Sbjct: 543  KKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602

Query: 575  ----------HRGERGP----QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620
                      H     P     GPPGP GD G+ G  G  G  G+PG  GPRG  GP G 
Sbjct: 603  RPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662

Query: 621  PGAPGQPGMAGVDGPPG---PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677
            PG PG PG  G  G PG    K + G +G+ G PG  GNPGP G  G +G  GP G  G 
Sbjct: 663  PGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGE 722

Query: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737
            QG+PG  G PGA G   +PG++G  G  G  GP G +G IG PG  G+ G+DG RGL G 
Sbjct: 723  QGQPGPEGSPGAKG---YPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779

Query: 738  KGEKGEDGFPGF------KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 791
             G++G+ G PGF      +G  GL G+ GE+G  GP G  G  G  G  GP G PGP G 
Sbjct: 780  PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839

Query: 792  AG------------EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGP 839
             G            +KG+ GVPG+ G PG QG KGS G PGFPGA G+ G  G  G  G 
Sbjct: 840  KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899

Query: 840  RGQRGPTGPRGSRGARGPTGKPGP---KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 896
             G  GP GP G  G  GP G  GP   KG  G  G PGP G+ GP+G +GP+G PG  G 
Sbjct: 900  IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 897  PGPPGKDGLPGHPGQ---RGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH------ 947
             G PG+ G PG PG    +GE G  G+ GP G  G +G  G  GE G +GE+G       
Sbjct: 960  EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP 1019

Query: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007
            PG PGP G  G PG  G  G  G+PGPQG  G  GP G+RG  G RG  G  G  G +G 
Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGS 1079

Query: 1008 EGPQGPPGPVGSPGERGSAGTAGPIG------LPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061
             G +GPPGP G PG  G  G AG  G       PG PGP GPPG  G  G PG +GPQGP
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121
             G  G  GP G PG  G  G PGE G KG++G  G  G +G  G+ G PG  G  GP+G 
Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE------------ 1169
             G+ G  G+PGP G+    G+KG EG  G  GPPGP G+ G+ GP G+            
Sbjct: 1200 DGLKGDRGDPGPDGEH---GEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256

Query: 1170 ---KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1226
               KG  G +G MG PG PGP G  GP G+ G  GP G+ G +G  GE G  G  G+ G 
Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316

Query: 1227 PGEAGVGGPKGERGEKGEAG-PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-------- 1277
             G  G  GPKGE+GE+GE G   G  GPPG +GP GD G +G PG  G+PG         
Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376

Query: 1278 ----------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1327
                      PGP G PGP G  G  G KG+ G  G PG  G  G  G PGP G  G  G
Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436

Query: 1328 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1387
              G  G  G  G  G+AG +G  G  G  GP GPAGK G  G+ G+P   G QG PG  G
Sbjct: 1437 LEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLP---GAQGPPGFKG 1493

Query: 1388 QDGPPGPMGPP---------GLPGLKGDPGSK------GEKGHPGLIGLIGPPGEQGEKG 1432
            + G PG +GPP         GLPG +G+PGSK      GE G PG+ GL GP G  G+ G
Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG 1553

Query: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1492
             +G+ G +G PG  G  GI GP G LGP G PG  G +G +G+ G  GP G  G  G PG
Sbjct: 1554 FKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPG 1613

Query: 1493 PPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILD--YSDGMEEIFGSLNSLKQD 1550
            PPG PG P + +Q   + ++ +T   T G       +  D    D   EIF +L+ L   
Sbjct: 1614 PPGPPGGPIQ-LQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQGGEIFKTLHYLSNL 1672

Query: 1551 IEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCI 1610
            I+ +K P+GT+ NPAR C+DL        DG YW+DPN GCS D+ +V CNFT GG+TC+
Sbjct: 1673 IQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVSCNFTHGGQTCL 1732

Query: 1611 YPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQN 1670
             P   S+                 EF              +I+ VQM FL LL++   Q+
Sbjct: 1733 KPITASK----------------VEF--------------AISRVQMNFLHLLSSEVTQH 1762

Query: 1671 FTYHCHQSAAWYDVSSGSYDK-ALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-YEKTV 1728
             T HC     W + +  +  K A+RF   N +          +   DGC  + G + +T+
Sbjct: 1763 ITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGCKVQDGRWHQTL 1822

Query: 1729 IEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766
                T    Q+PI+ V         +++  EVGP CFL
Sbjct: 1823 FTFRTQDPQQLPIISVDNLPPASSGKQYRLEVGPACFL 1860



 Score =  345 bits (884), Expect = 3e-94
 Identities = 216/514 (42%), Positives = 264/514 (51%), Gaps = 59/514 (11%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGPAGPAG 412
            P  PP     PG+P E           G  G+ G  G P   E G++ + G PG  G +G
Sbjct: 1148 PKGPPGAVGEPGLPGEA----------GMKGDLGPLGTPG--EQGLIGQRGEPGLEGDSG 1195

Query: 413  IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG-TMLMLPF-RYGGDGSKGPTI 470
             MGP GL+G  G PG  G+ G  G+ GL G DG PGPPG T +  P  + G  G KG T 
Sbjct: 1196 PMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTG 1255

Query: 471  SAQEAQAQAILQQARI----ALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
            +      Q  L +  +       G PGP G  G  GP G PG  GA+GE G  G  G +G
Sbjct: 1256 AKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKG 1315

Query: 527  VQGPPGPTGKPGKRGRPGADG-GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 585
            + GP GP G  G++G  G DG   G PG PG +G  G  G  G PGD G+ G+ G QG  
Sbjct: 1316 IVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLR 1375

Query: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG---APGQPGMAGVDGPPGPKGNM 642
            G PG    +G+ G  GPRG PG  G +G  GP+G  G   APG+ G+ G+ G PGP+G +
Sbjct: 1376 GKPGQ---QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV 1432

Query: 643  GPQ------GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP 696
            G Q      G  G PG+ G  G QG  G  G  GP G  G +G PG+AGLPGA GPPG  
Sbjct: 1433 GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGF- 1491

Query: 697  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 756
              +G+SG  G LGPPG             +G +G  GL G++GE G  G PG  G+MG  
Sbjct: 1492 --KGESGLPGQLGPPGK------------RGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537

Query: 757  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 816
               G  G  GP+G  G  G KG  GP G PG  G+ G  G LG+ G  G PG +G KGS 
Sbjct: 1538 ---GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGS- 1593

Query: 817  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 850
                     G+ G +G  G PGPRG+ GP GP G
Sbjct: 1594 --------RGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  107 bits (267), Expect = 1e-22
 Identities = 140/512 (27%), Positives = 174/512 (33%), Gaps = 101/512 (19%)

Query: 1034 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP------------GPAGPAG 1081
            LP   GP+G   PA     P    P  P     V GP   P             P  PA 
Sbjct: 282  LPAGRGPRGTVAPATPT-KPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPAS 340

Query: 1082 SPGEDGD-KGEIGEPGQK--GSKGDKGENGPPGPPGLQ-GPVGAPGIAGGDGEPGPRGQQ 1137
              G     +    +P QK   +K  K     P  P     P+ +P        P  +   
Sbjct: 341  VGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSP-------HPTQKTAP 393

Query: 1138 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1197
              F +      +  P    P+  +     P EK    + G   PP PP  R P  P  + 
Sbjct: 394  SSFTKSALPTQKQVPPTSRPVPAR--VSRPAEKPIQRNPGMPRPP-PPSTR-PLPPTTSS 449

Query: 1198 GPQGPPGSVGSVGGV-GEKGEPGEAG---NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1253
              +  P    +   +     +P  A    +  PP  A    P    G      PP    P
Sbjct: 450  SKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVP 509

Query: 1254 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
            P +    G   P+  P  V  PG   P G   P G +                    S +
Sbjct: 510  PTS----GTSTPRTAPA-VPTPGS-APTGSKKPIGSEA-------------------SKK 544

Query: 1314 AGPPGPPGKRGP--PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1371
            AGP   P K  P  PG A  +    +   +       P  +T P     PA     + L 
Sbjct: 545  AGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPA-----QFLS 599

Query: 1372 GIPGPVGE-QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1430
              P P      +   AG    P  MGPPG          KG+ G PG  GL G PG  G 
Sbjct: 600  SSPRPTSSGYSIFHLAGSTPFPLLMGPPG---------PKGDCGLPGPPGLPGLPGIPGA 650

Query: 1431 KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---------------------PGP 1469
            +G RG PG  G+PG      +PGP G  G  G PGL                     PGP
Sbjct: 651  RGPRGPPGPYGNPG------LPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGP 704

Query: 1470 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
             G KG+KG  GPAG  G+ G PGP GSPG  G
Sbjct: 705  PGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 52/231 (22%), Positives = 102/231 (44%), Gaps = 21/231 (9%)

Query: 17  FTVTTLALTFLFQAREVRGAAP-VDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYR 75
           F  + + ++F       +GA   VD+L+ L    +  G     G    +       + + 
Sbjct: 23  FLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQ-------SGFI 75

Query: 76  VSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEV--GR 133
            +++A+L APT  + P     E  +++ ++   +   +FL ++ ++    Q+G++   G+
Sbjct: 76  FTQRARLQAPTGTVIPAALGTE-LALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGK 134

Query: 134 SPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRS 193
           + V     H G      + L    ++ DG+WH +A+ +  +TVT++  C ++    L   
Sbjct: 135 TVV-----HLGSRRSVAFDL----DMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPF 185

Query: 194 ER-AIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDC 243
            R   +D  G  +FG        FEG + QF I    + A++YC H    C
Sbjct: 186 HRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQC 236


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  936 bits (2418), Expect = 0.0
 Identities = 569/1328 (42%), Positives = 664/1328 (50%), Gaps = 215/1328 (16%)

Query: 383  YGEKGQKGEPAVV----------EPGML-------VEGPPGPAGPAGIMGPPGLQGPTGP 425
            Y  KGQKGEP  +          +PG+         +GPPG A   G  G PG  G  G 
Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGS 1309

Query: 426  PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG-PTISAQEAQAQAILQQA 484
            PG  G+ G PG PGL G+ GLPGP G     P   G  G KG P    Q    +      
Sbjct: 1310 PGRAGNPGTPGAPGLKGSPGLPGPRGD----PGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365

Query: 485  RIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD--PGPQGPRGVQGPPGP------TGK 536
            R   +G PGP G  G  GP+G PG  G  G  G    G +G RG +GPPGP       G+
Sbjct: 1366 R---KGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGE 1422

Query: 537  PGKRGRPGADGGRGMPGEPGAKGDRG--FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 594
            PG  G PG+ G +G  G PG KG++G   DG PGLPG  G  GE+GP+GPPG  G  G R
Sbjct: 1423 PGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482

Query: 595  GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 654
            G  G +G  G  GE GP G  G RG PG  G+PG  G +GPPGP G  G +GEPG PG  
Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 655  -----------------GNPGPQGLPGPQGPIGP-----PGEKGPQGKP---GLAGLPGA 689
                             G  GP+G  G QG  GP     PG+ GP+G P   G  GL G 
Sbjct: 1543 AVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGR 1602

Query: 690  DGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV---RGLKGSKGEKGEDGF 746
             GPPG  G  G+ G+ G  GPPGP GP G  G  G KG +G     GL G  GE+G  G 
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGA 1662

Query: 747  PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK-LGVPGLPG 805
            PG +G +G KGD+G+ G+ G  G  G  GPKG  G  G PGP G+  + G      G PG
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722

Query: 806  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP-------- 857
              G++GP+G  G PG PGA GE+G  G  G PGP+G  G  GP G +G RGP        
Sbjct: 1723 DRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 858  -TGKP---GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK---DGLPGHPG 910
              GKP   GP G +G  G  G PG  G  G +G  G PGP GPPG PGK   DG PG  G
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 911  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK----- 965
            + GE G  G+ G  G  G  G  G  G  GP GERG PG  GP G  GLPG  G      
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902

Query: 966  EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA------------------------ 1001
             G  G  GP+G  G+ G  G +G PGERGL G  G+                        
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962

Query: 1002 ---------------PGLKGGEGPQGPP---GPVGSPGERGSAGTAGPIGLPGRP----G 1039
                            G KG  G QGPP   GP+G PGERG  G  G  G  G P    G
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALG 2022

Query: 1040 PQGPPGPA---------------------GEKGAPGEKGPQGPAGRDGVQ---GPVGLPG 1075
             +GPPGP+                     GE G PGE+G +G  G  G Q   GP GLPG
Sbjct: 2023 ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPG 2082

Query: 1076 PAGPAGSPGE--------DGDKGEIGEPGQKGSKGDKGENGPPGP------PGLQGPVGA 1121
              GP G PG          G  GE G PG KG+KG+ G NG  GP      PG++G  G 
Sbjct: 2083 TPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
            PG  G DG PG  G++GM G +G  G +G  GPPGP+G  G PGPPG  G  G  GP GP
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202

Query: 1182 ------PGPPGP--RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1233
                  PG  GP  RG  GP GA G  GPPG  G VG  G  G PG+ G  G PG  G  
Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262

Query: 1234 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP--VGFPGDPGPPGEPGPAGQDG 1291
            G  G+ G++G  G PG+ G PG  GP G+ GP G PG   VG PG  G  G PG    D 
Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322

Query: 1292 VG--------------GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQ 1335
            VG              G+KGE G  G+PG PG  G+ G PGP G +G PG    G+ G  
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPP 2382

Query: 1336 GEKGAKGEAGAEGPPGKTGPV------GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1389
            G  G KG+ G  G PG  G V      GP+G  G+PGP G RG+ GP G +G+PG  G  
Sbjct: 2383 GPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP 2442

Query: 1390 GPPGPMGPPGLPGLKGD--------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1441
            GPPG +GPPG  GLKGD        PG +GE+G PG+ G  G PG++G +G  G PG++G
Sbjct: 2443 GPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRG 2502

Query: 1442 SPGAKGDGGIPGPAGP-------LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1494
              G KGD G  G  G        LGPPGP G  G  G +G +G  G  G +GD+G PG  
Sbjct: 2503 ERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDK 2562

Query: 1495 GSPGPPGE 1502
            GS G PG+
Sbjct: 2563 GSKGEPGD 2570



 Score =  921 bits (2381), Expect = 0.0
 Identities = 560/1305 (42%), Positives = 643/1305 (49%), Gaps = 221/1305 (16%)

Query: 381  GAYGEKGQKGEPAVVEPGMLV--EGP--------PGPAGPAGIMGPPGLQGPTGPP---- 426
            G  G +G KGEP    PG ++  EGP        PGP+GP G  GP G  GP GPP    
Sbjct: 1338 GERGPRGPKGEPGA--PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 427  -------GDPGDRGP---------PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 470
                   GD G+RGP         PG PGLPG  G PGP G +       G  G KG   
Sbjct: 1396 TAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPV-------GPPGKKGEKG 1448

Query: 471  SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP---QGPRGV 527
             +++               G PG  G  G  GP G PG+ G KG+ G PGP    G +G 
Sbjct: 1449 DSEDGAP------------GLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE 1496

Query: 528  QGPPGPTGK---PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP--------GDKGHR 576
            +GPPGP G    PG  GRPGA G  G PG  G +G++G  G PG P        G KG +
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 577  GERGPQGPPGPPGDDGMRGEDGEI-----GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG 631
            G+ GP GP G  G  G RG  G +     GP+G PG+ GP GL G  G PG  G PG  G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616

Query: 632  VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP------GPQGPIGPPGEKGPQGKPGLAG 685
              G PGP G +GP+G  G  G++G+ GP G P      G +G  G PG +GP G+ G  G
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 686  LPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----------------GYPGPRGVKGAD 729
             PG DG  G PG  G  G++G  GPPGP G +                G  GPRG KG  
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 730  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 789
            G+ G  G +G +G  G PG +GD G++G  GE G  GP G DG  G  G+ G  G  GP+
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 790  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 849
            G AG+ G  G  GLPG  G QG  G +G PG PG  GE       GKPG  G+ G  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGED------GKPGLNGKNGEPGDP 1850

Query: 850  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP--PGKDGLPG 907
            G  G +G  G  G  G  G DGP G  G  G  GPQGP G PGP GPPG   PG  G  G
Sbjct: 1851 GEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTG 1910

Query: 908  HPGQRGETGFQGKTGPPGPGGVVGPQG--------------------------------- 934
              G RGETG +G+ G PG  G+ G  G                                 
Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSF 1970

Query: 935  ---PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG----ISGKDGPAGLR 987
               P    GP G+ G  GPPG  G  G PG  G +G +GDPGPQG      G+ GP G  
Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPS 2030

Query: 988  GFPGERGLPGAQGAPGLKGGEGPQGPP---GPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044
            G  GE G PG  G PG  GG G  G P   G  G  GERG  G  GP GLPG PGP GPP
Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090

Query: 1045 GP--AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS-- 1100
            GP  + ++  PG  G QGP G  G +G  G  G  GP G  G  G KG+ GEPG +G   
Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150

Query: 1101 ----KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE---------- 1146
                 G++G  GP G PGLQGP G PG  GG G+PGP G  G+ G  G +          
Sbjct: 2151 NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG 2210

Query: 1147 -------------GARGFPGPPGPIGL---QGLPGPPGEKGE---------------NGD 1175
                         GA G PGPPGP GL   QG PG PG+ GE               +GD
Sbjct: 2211 ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGD 2270

Query: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPGS--VGSVGGVGEKGEPGE-----AGNPGPPG 1228
             G  G PG PG  GP GP G  GP G PG   VG  G  GEKG PG       G PG  G
Sbjct: 2271 RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG 2330

Query: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGEPGP 1286
            + G+ GP+GE+GE G AG P         G PG+DG KG PGP GF GDP  G PG PGP
Sbjct: 2331 DRGLPGPRGEKGEAGRAGEP---------GDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381

Query: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1346
             G  GV GD G  G PG PG  G  G+ GP G  G+ GP G  G  G  G +G  G  G 
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP 2441

Query: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406
             GPPG  GP G  G  G  G  G+ G+PGP GE+G PG  G+DG PG  GP GL G  G 
Sbjct: 2442 PGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500

Query: 1407 PGSKGEKGHPGLIGL----------IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG 1456
             G +GEKG  G  GL          +GPPG +G KGD G  G +G  G KG  G  G  G
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG 2560

Query: 1457 PLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
              G  G PG  G  G  G +G  GP GQ G +G+PG PGSPG  G
Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605



 Score =  914 bits (2362), Expect = 0.0
 Identities = 560/1281 (43%), Positives = 647/1281 (50%), Gaps = 191/1281 (14%)

Query: 381  GAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIMGPPGLQGPTGPPG-----DPGDRGP 434
            G  GE G+ G+PAVV P +   +G  G  GPAG  G  G+QG  GPPG     DPG +G 
Sbjct: 1531 GEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGD 1590

Query: 435  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494
            PG  G  G  G  GPPG         G  G KG                      GPPGP
Sbjct: 1591 PGDRGPIGLTGRAGPPGDS-------GPPGEKGDP-----------------GRPGPPGP 1626

Query: 495  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---PTGKPGKRGRPGADGGRGM 551
            +G  GR G VG  G  G  G+ G PG  G RG++G PG   P G+ G +G PG DG  G 
Sbjct: 1627 VGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS 1686

Query: 552  PGEPGAKGDRGFDGLPGLPG----------DKGHRGERGPQGPPGPPGDDGMRGEDGEIG 601
            PG  G KGDRG  G PG PG          +KG  G+RG +GP GP GD G+ G  GE G
Sbjct: 1687 PGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746

Query: 602  ---------PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPG 652
                     P+G PG  GP G  G RG PG  G+ G+ G  G  GP G  G  G+ G PG
Sbjct: 1747 IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG 1806

Query: 653  QQGNPG---PQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG------ 703
            + G PG    QGLPGP GP G PG+ G  GKPGL G  G  G PG  G++G+ G      
Sbjct: 1807 RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASG 1866

Query: 704  ---------EKGALGPPGPQGPIGYPGP-----RGVKGADGVRGLKGSKGEKGEDGFPGF 749
                     E+GA G  GPQGP G PGP     +G  G  G  G KG +GE G  G  G 
Sbjct: 1867 REGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGL 1926

Query: 750  KGDMGLKGDRGEVGQI------------------------------------GPRGEDGP 773
             G+ GL+G+ G V  +                                    GP+G+ G 
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE 1986

Query: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY-------PGRQGPKGSTGFPGFPGANG 826
            +GP G+ GP G PG  G  G++G  G  G PG        PG  G  G  G PG PG  G
Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046

Query: 827  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP--------PGPPGE 878
              G  G AG+PG RG+RG  G RG +G  GP G PG  G  G  GP        PG  GE
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 879  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG-PG--GVVGP--- 932
            +GP G +G  G PG  G  GP G  G+PG  G RGE G +G+ G PG PG  G+ GP   
Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166

Query: 933  ---QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP-----QGISGKDGPA 984
               QGP G  GP+G  G PGPPG PG  G  G  G  G KG+PG      +G++G  G  
Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAV 2226

Query: 985  GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG------------SPGERGSAGTAGPI 1032
            GL G PG  GL G QG+PGL G  G  G PG  G            SPG  GS G  GP+
Sbjct: 2227 GLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPV 2286

Query: 1033 GLPGRPGPQGPPGPA--GEKGAPGEKGPQGP-----AGRDGVQGPVGLPGPAGPAGSPGE 1085
            G  G PGP G PG A  G  GA GEKG  G       G  G +G  GLPGP G  G  G 
Sbjct: 2287 GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346

Query: 1086 DGDKGEIGEPGQKGSKGDKGENGPPGP--PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143
             G+ G+ GE GQKG+ G KG  G PG   PG  GP G PG+ G  G PG  G  G+ G  
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFP 2406

Query: 1144 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1203
            G  G RG  G PGP G +GL GPPG +G  G   P+GPPGPPG  GP G +G  G +G P
Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPG---PLGPPGPPGSVGPPGASGLKGDKGDP 2463

Query: 1204 GSVGSVGGVGEKGEPG---EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG-- 1258
            G VG  G  GE+GEPG   E G PG  G  G+ GP G RGE+GE G  G+AG  G KG  
Sbjct: 2464 G-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522

Query: 1259 -----PPGDDGPKGNPG---PVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGP 1310
                 PPG  G KG+ G   P G  GD GP G+ G  G  G    KGE GD G  G PG 
Sbjct: 2523 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG---SKGEPGDKGSAGLPGL 2579

Query: 1311 SGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1370
             G  GP G PG  G PG  G+ G+ G  G +GE   +G  G  GP G +G  G  G  GL
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE---KGDVGFMGPRGLKGERGVKGACGL 2636

Query: 1371 RGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG---EKGHPGLIGLIGPPGE 1427
             G  G  GE G PG  G  G  G MG PG+PG  G PG +G    KG  G  G  GP G+
Sbjct: 2637 DGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGD 2696

Query: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1487
            QGEKG+RG PG  G PG  G+    G AGP GPPG  G  GP+G +G KG  GP G++  
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGN---DGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGER-V 2752

Query: 1488 SGLPGPPGSPGPPGEVIQPLP 1508
             G PG PG+PG  GE  +P P
Sbjct: 2753 VGAPGVPGAPGERGEQGRPGP 2773



 Score =  882 bits (2280), Expect = 0.0
 Identities = 541/1248 (43%), Positives = 627/1248 (50%), Gaps = 256/1248 (20%)

Query: 489  RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548
            +G PG MGL G+ GP   PG  G  G +G PGPQGP G     G  G PG  GRPG+ G 
Sbjct: 1256 KGEPGEMGLRGQVGP---PGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR 1312

Query: 549  RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD------DGMRGEDGEIGP 602
             G PG PGA G +G  GLPG  GD G RG RGP+G PG PG        G+ G  G+ GP
Sbjct: 1313 AGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGP 1372

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP------PGQQGN 656
             G PG  GP G  GPRG PG PG           G KG+ G +G PGP      PG+ G 
Sbjct: 1373 SGPPGPRGPLGDPGPRGPPGLPGT-------AMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425

Query: 657  PGPQGLPGPQGPIGPPGEKGPQGK-----PGLAGLPGADG------PPG---------HP 696
            PG  G PGPQGP+GPPG+KG +G      PGL G PG+ G      PPG          P
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 697  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD---- 752
            G  G++GEKG  GPPGP G  G PG  G  GA G  G  G  G +GE G PG  GD    
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 753  ----MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGY 806
                 G KG++G+VG  GPRG  G +G +G  G    GDPGP G  G++G +G+ G  G 
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 807  PGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP------------RGSRGA 854
            PG  GP G  G PG PG  G  G RG  G+ G +G  GP G             RG+ G 
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 855  RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP--------------------- 893
            RGP G+ G +G  G DG  G PG  GP+G +G  G PGP                     
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 894  -KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952
             +GP GP G  GLPG PG+RG  GF+G   PPGP G  G +GP GE G   +RG PG  G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRG---PPGPQGDPGVRGPAGEKG---DRGPPGLDG 1779

Query: 953  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012
              G  G PGAAG  G  G  G  G  G+DG  GLRG   E+GLPG  G PGL G  G  G
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG---EQGLPGPSGPPGLPGKPGEDG 1836

Query: 1013 PPG---PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069
             PG     G PG+ G  G  G  G  G  G +G  GP GE+GAPG  GPQGP G  G  G
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 1070 PVG-----LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD--------------------- 1103
            P G     +PG  GP G  GE G KGE G PG++G +G+                     
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASAL 1956

Query: 1104 ------------------------KGENGPPGPPGLQGPVGAPG---IAGGDGEPGPRGQ 1136
                                    KG++G  GPPG +GP+G PG   + G  G+PGP+G 
Sbjct: 1957 REIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP 2016

Query: 1137 QGM-FGQKGDEGARGFPGPPGPIGLQGLPGP---------PGEKGENGDVG--------- 1177
             G+  G++G  G  G  G PG  G+ GLPG          PGE+GE G+ G         
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076

Query: 1178 PMGPPGPPGPRGPQGPN--------GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
            P G PG PGP GP GP         G  G QGPPG  G+      KGEPG  G+ GP G+
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA------KGEPGSNGDQGPKGD 2130

Query: 1230 AGVGGPKGERGEKGEAGP------PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283
             GV G KG+RGE G  G       PG  G  G +G PG  GP+G PGPVG  GDPGPPG 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 1284 PG------PAGQDGVGGDKGEDGDPGQ-----------PGPPGPSGEAGP---PGPPGKR 1323
            PG      P G  G+ G+ GE G PG+           PGPPGPSG  GP   PG PG+ 
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 1324 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG-------------- 1369
            G  G  GA GR G  G  G+ G+ G PG  G  GP GP G+PGP G              
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 1370 -----------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG---LKGDPGSKGEKGH 1415
                       L G PG  G++GLPG  G+ G  G  G PG PG    KG PG KG KG 
Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 1416 PGL--IGLIGPPGEQGEKGDRGLPGTQGSPGA---------KGDGGIPGPAGP---LGPP 1461
            PG+   G  GPPG  G KGD GLPG  G+PG          +G+ G PGP+G     GPP
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 1462 GPPGLPGPQGPKGNKGSTGP---AGQKGDSGLPGPPGSPGPPGEVIQP 1506
            G  G+PGP GP G  GS GP   +G KGD G PG  G PGP GE  +P
Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEP 2477



 Score =  860 bits (2223), Expect = 0.0
 Identities = 519/1219 (42%), Positives = 607/1219 (49%), Gaps = 149/1219 (12%)

Query: 355  TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM 414
            + PP E+  PG P             G  GEKG +G P   +PG+     PG AG  G+ 
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPR-GRDGEVGEKGDEGPPG--DPGL-----PGKAGERGLR 1660

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGL---------PGPPGTMLML--------- 456
            G PG++GP G  GD GD G  GR G PG+ G          PGPPG ++           
Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGE 1720

Query: 457  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 516
            P   G +G +GP          A  ++     RGPPGP G  G  GP G  G  G  G  
Sbjct: 1721 PGDRGQEGPRGP--KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD 1778

Query: 517  GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 576
            G  G  G  G  GP GP G  GK G PG DG  G+ GE G  G  G  GLPG PG+ G  
Sbjct: 1779 GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKP 1838

Query: 577  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMA 630
            G  G  G PG PG+DG +GE G+ G  G  G  GP+G      +LGP+G PG PG  G  
Sbjct: 1839 GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898

Query: 631  G--VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG------------------ 670
            G    G PG  G  G +GE G  G+QG PG +GL G  G +                   
Sbjct: 1899 GQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALRE 1958

Query: 671  ---------------PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQG 715
                           P   +GP+G  G  G PG +GP G PG+ G  G++G  GP GP G
Sbjct: 1959 IVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPG 2018

Query: 716  PI----GYPGPRGVKGADG---VRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768
                  G PGP G+ G  G   + GL G  G  GE G PG +G+ G KG+RGE G+ GP 
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078

Query: 769  GEDGPEGPKGRAGP---TGDPGP--SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823
            G  G  GP G  GP     +PGP  SG+ G  G  G  G PG  G QGPKG  G PG  G
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 824  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 883
              GE G RG  G PG  G+RG  GP G  G +GP G PGP G  G  GPPG PG  GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 884  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 943
            PQGP G  G  G  GPPG+       G  G TG  G  GPPGP G+VGPQG  G  G +G
Sbjct: 2199 PQGPSGLKGEPGETGPPGR-------GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVG 2251

Query: 944  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER--GLPGAQGA 1001
            E G PG PG  G  G  G  G  G  G PG  G  G  G  G  G PG+   GLPGA+G 
Sbjct: 2252 ETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGE 2311

Query: 1002 PGLKGG--------EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG-- 1051
             G  GG         G +G  G  G  GE+G AG AG  G PG  G +G PGP G KG  
Sbjct: 2312 KGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDP 2371

Query: 1052 ---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108
                PG  GP GP G  G  G  GLPG  G  G PG+ G +GE+G+PG  G +G  G  G
Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431

Query: 1109 ---------PPGPPGLQGPVGAPGIAGGDGEPG-----PRGQQGMFGQKGDEGARGFPGP 1154
                     PPGPPG  GP GA G+ G  G+PG     PRG++G  G +G++G    PG 
Sbjct: 2432 REGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR---PGQ 2488

Query: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG-------PRGPQGPNGADGPQGPPGSVG 1207
             GP GL G PG  GE+GE GDVG  G  G  G       P GP+G  G  G +GP G  G
Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG 2548

Query: 1208 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1267
              G  G+ G+PG+ G+ G PG+ G  G  G RG  G  G PGAAG PG  G PG DG  G
Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPG 2608

Query: 1268 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1327
              G  G  G  GP G  G  G  G  G  GE GD G+ GPPG  G AG  G  G+ G PG
Sbjct: 2609 IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668

Query: 1328 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1387
             +GA G++G  G KG+ G +G P   GP G QG  G+ G  G+ G PGP G     G+AG
Sbjct: 2669 QSGAPGKEGLIGPKGDRGFDGQP---GPKGDQGEKGERGTPGIGGFPGPSGND---GSAG 2722

Query: 1388 QDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1447
              GPPG +GP G  GL+G  G +            GPPGE+      G PG  G+PG +G
Sbjct: 2723 PPGPPGSVGPRGPEGLQGQKGER------------GPPGERVV----GAPGVPGAPGERG 2766

Query: 1448 DGGIPGPAGPLGPPGPPGL 1466
            + G PGPAGP G  G   L
Sbjct: 2767 EQGRPGPAGPRGEKGEAAL 2785



 Score =  856 bits (2212), Expect = 0.0
 Identities = 537/1275 (42%), Positives = 628/1275 (49%), Gaps = 277/1275 (21%)

Query: 467  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
            GP++    +     L QA    +  P P        PV  P     KG+ G+PG  G RG
Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPC-------PVYCP-----KGQKGEPGEMGLRG 1266

Query: 527  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586
              GPPG  G PG+ G PG    +G PG   AKG+RGF G  G PG  G  G       PG
Sbjct: 1267 QVGPPGDPGLPGRTGAPGP---QGPPGSATAKGERGFPGADGRPGSPGRAGN------PG 1317

Query: 587  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------PGMAG------VDG 634
             PG  G++G  G  GPRG PGE GPRG   P+G PGAPGQ      PG+ G        G
Sbjct: 1318 TPGAPGLKGSPGLPGPRGDPGERGPRG---PKGEPGAPGQVIGGEGPGLPGRKGDPGPSG 1374

Query: 635  PPGP-----------------------KGNMGPQGEPGP------PGQQGNPGPQGLPGP 665
            PPGP                       KG+ G +G PGP      PG+ G PG  G PGP
Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGP 1434

Query: 666  QGPIGPPGEKGPQ-----GKPGLAGLPGAD------GPP---------GHPGKEGQSGEK 705
            QGP+GPPG+KG +     G PGL G PG+       GPP         G PG  G++GEK
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEK 1494

Query: 706  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD--------MGLKG 757
            G  GPPGP G  G PG  G  GA G  G  G  G +GE G PG  GD         G KG
Sbjct: 1495 GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKG 1554

Query: 758  DRGEVGQIGPRGEDGPEGPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815
            ++G+VG  GPRG  G +G +G  G    GDPGP G  G++G +G+ G  G PG  GP G 
Sbjct: 1555 EKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGE 1614

Query: 816  TGFPGFPGAN------------GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 863
             G PG PG              GEKG  G  G PG  G+ G  G RG+ G RGP G+ G 
Sbjct: 1615 KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD 1674

Query: 864  KGTSGGDGPPGPPGERGPQGPQGPVGFPGP----------------------KGPPGPPG 901
            +G  G DG  G PG  GP+G +G  G PGP                      +GP GP G
Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734

Query: 902  KDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPG 961
              GLPG PG+RG  GF+   GPPGP G  G +GP GE    G+RG PG  G  G  G PG
Sbjct: 1735 DPGLPGAPGERGIEGFR---GPPGPQGDPGVRGPAGEK---GDRGPPGLDGRSGLDGKPG 1788

Query: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP---GPVG 1018
            AAG  G  G  G  G  G+DG  GLR   GE+GLPG  G PGL G  G  G P   G  G
Sbjct: 1789 AAGPSGPNGAAGKAGDPGRDGLPGLR---GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845

Query: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP-----VGL 1073
             PG+ G  G  G  G  G  G +G  GP GE+GAPG  GPQGP G  G  GP      G+
Sbjct: 1846 EPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 1074 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGD------------------------------ 1103
            PG  GP G  GE G KGE G PG++G +G+                              
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 1104 ---------------KGENGPPGPPGLQGPVGAP---GIAGGDGEPGPRGQQGM-FGQKG 1144
                           KG++G  GPPG +GP+G P   G+ G  G+PGP+G  G+  G++G
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 1145 DEGARGFPGPPGPIGLQGLP---------GPPGEKGENGDV---------GPMGPPGPPG 1186
              G  G  G PG  G+ GLP         G PGE+GE G+          GP G PG PG
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 1187 PRGPQGPN--------GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1238
            P GP GP         G  G QGPPG  G+      KGEPG  G+ GP G+ GV G KG+
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGA------KGEPGSNGDQGPKGDRGVPGIKGD 2139

Query: 1239 RGEKGEAGP------PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP------GP 1286
            RGE G  G       PG  G  G +G PG  GP+G PGPVG  GDPGPPG P      GP
Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP 2199

Query: 1287 AGQDGVGGDKGEDGDPGQ-----------PGPPGPSGEAGP---PGPPGKRGPPGAAGAE 1332
             G  G+ G+ GE G PG+           PGPPGPSG  GP   PG PG+ G  G  GA 
Sbjct: 2200 QGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP 2259

Query: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG-----LRGIPGPVGEQGLPGAAG 1387
            GR G  G  G+ G+ G PG  G  GP GP G+PGP G     + G+PG  GE+G PG   
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 1388 QD--GPPGPMGPPGLP---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL-----P 1437
             D  G PG  G  GLP   G KG+ G  GE G PG  G  G PG +G KGD G+     P
Sbjct: 2320 GDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSP 2379

Query: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK------GDSGLP 1491
            G  G PG KGD G+PG     G PG  G PG  GP+G  G  GP+G++      G  G+P
Sbjct: 2380 GPPGPPGVKGDLGLPGLP---GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436

Query: 1492 GPPGSPGPPGEVIQP 1506
            GP G PGPPG V  P
Sbjct: 2437 GPLGPPGPPGSVGPP 2451



 Score =  778 bits (2010), Expect = 0.0
 Identities = 465/1082 (42%), Positives = 556/1082 (51%), Gaps = 169/1082 (15%)

Query: 581  PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 640
            P+G  G PG+ G+RG+ G  G  GLPG  G  G  GP G+  A G+ G  G DG PG  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 641  NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG-LPGADGPPGHPGKE 699
              G  G PG PG +G+PG   LPGP+G  G  G +GP+G+PG  G + G +GP    G  
Sbjct: 1312 RAGNPGTPGAPGLKGSPG---LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP----GLP 1364

Query: 700  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 759
            G+ G+ G  GPPGP+GP+G PGPRG  G  G   +KG KG++GE G PG  G+ G+    
Sbjct: 1365 GRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT-AMKGDKGDRGERGPPG-PGEGGIAP-- 1420

Query: 760  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF- 818
            GE G  G  G  GP+GP G  G  G+ G S    E G  G+PG PG PG QGP+G  G  
Sbjct: 1421 GEPGLPGLPGSPGPQGPVGPPGKKGEKGDS----EDGAPGLPGQPGSPGEQGPRGPPGAI 1476

Query: 819  -----PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873
                  GFPG  GE G +G  G PGP G RG  G  G  GA+GP G PGP G  G  G P
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 874  GPPGER-----------------GPQGPQGPVGFPGPKGPPGP--PGKDGLPGHPGQRGE 914
            G PG+                  GP GP+G  G  G +GPPG   PG  G  G PG RG 
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 915  TGFQGKTGPPG----PG-----GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965
             G  G+ GPPG    PG     G  GP GP G  G  GE G  G  GPPG+ GLPG AG+
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 966  EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV-------- 1017
             G +G PG +G  G+ G  G  G  G  G PG+ G  G +G  GP GPPG +        
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 1018 --GSPGERGSAGTAGPIGLPGRPGP---------QGPPGPAGE---KGAPGEKGPQGPAG 1063
              G PG+RG  G  GP G PG PG          +GPPGP G+   +G  GEKG +GP G
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776

Query: 1064 ---RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120
               R G+ G  G  GP+GP G+ G+ GD G  G PG +G +G  G +GPPG PG  G  G
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836

Query: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1180
             PG+ G +GEPG  G+ G  G+KGD GA G  G  GP G +G PG  G +G  G  GP+G
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 1181 PPGP--------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE------------------ 1214
            PPG          GP+G +G  G+ G QG PG  G  G  G                   
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASAL 1956

Query: 1215 ---------------------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1253
                                 +G  G++G  GPPG+ G  G  GERG KG+ G PG  GP
Sbjct: 1957 REIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP 2016

Query: 1254 PGA----KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309
            PG     +GPPG  G  G PG  G PG PG  G  G AG+ G  G++GE G+ G+ G  G
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076

Query: 1310 PSGEAGPPGPPGKRGP--------PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1361
            P G  G PGPPG  GP        PG +G +G  G KGAKGE      PG  G  GP+G 
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGE------PGSNGDQGPKGD 2130

Query: 1362 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG---SKGEKGHPGL 1418
             G PG +G RG PGP G+ G PG  G+ G  GP G PGL G +G PG     G+ G PG 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 1419 IGLIGPPGEQGEKGDRGLPGTQGSPG--------AKGDGGIPGPAGPLGPPGPPGLPGPQ 1470
             GL GP G QG  G +G PG  G PG        A G  G PGP+G +GP G PGLPG  
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 1471 GPKGNKGSTG---PAGQKGDSGLPGPPGSP------------GP---PGEVIQPLPILSS 1512
            G  G  G+ G    +G+ GD G PG PGSP            GP   PG+ +  LP    
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 1513 KK 1514
            +K
Sbjct: 2311 EK 2312



 Score =  705 bits (1820), Expect = 0.0
 Identities = 427/959 (44%), Positives = 499/959 (52%), Gaps = 101/959 (10%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP--PGLQGPTGPPGDPGDRGPPGRP 438
            G  G KG++G P ++ P    +GPPG  GP G  G   PG+ G TGP GD G+ G  G  
Sbjct: 1869 GRDGPKGERGAPGILGP----QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 439  GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA------QEAQAQAILQQARIALRGPP 492
            GLPG  GL G PG++  +       G K   +        + + +   + + R   +G  
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 493  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 552
            G  G  G+ GP+G PG  G KG+ GDPGPQGP G+          G+RG PG  G  G P
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLA--------LGERGPPGPSGLAGEP 2036

Query: 553  GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 612
            G+PG         +PGLPG  G  GE G  G  G  G+ G RGE G  GP GLPG  GP 
Sbjct: 2037 GKPG---------IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 613  GLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 672
            G  GP+ +   PG PG++G  GPPG KG    +GEPG  G QG  G +G+PG +G  G P
Sbjct: 2088 GPPGPKVSVDEPG-PGLSGEQGPPGLKG---AKGEPGSNGDQGPKGDRGVPGIKGDRGEP 2143

Query: 673  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR 732
            G +G  G PGL G  G  GP G PG +G  G  G +G  G  GP G PG  G  G  G  
Sbjct: 2144 GPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPS 2203

Query: 733  GLKGSKGEKGEDG--FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG--- 787
            GLKG  GE G  G    G  G +GL G  G  G +GP+G  G  G  G  G  G PG   
Sbjct: 2204 GLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDG 2263

Query: 788  PSGQAGEKGKLGVPGLPGYPGRQGPKGS---TGFPG-----FPGANGEKGARG-----VA 834
             SG+ G++G  GVPG PG PG  GPKG    TG PG      PGA GEKGA G     + 
Sbjct: 2264 ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323

Query: 835  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 894
            G+PG +G RG  GPRG +G  G  G+PG  G  G  G PGP G +G  G   P G PGP 
Sbjct: 2324 GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP-GSPGPP 2382

Query: 895  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP---P 951
            GPPG  G  GLPG PG  G  GF G+TGP G  G  GP G  G  GP G  G PGP   P
Sbjct: 2383 GPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP 2442

Query: 952  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1011
            GPPG  G PGA+G +G KGDPG           GL G  GERG PG +G  G  G EGP+
Sbjct: 2443 GPPGSVGPPGASGLKGDKGDPG----------VGLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQ----GPPGPAGEKGAPGEKGPQGPAGRDGV 1067
            G  GP GS GERG  G  G  GL G  G      GPPGP G KG  GE+GP+G    DG 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG---LDGD 2549

Query: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGAPGI 1124
            +GP G  G  G  GS GE GDKG  G PG +G  G +G+ G    PG PG  G  G PGI
Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609

Query: 1125 AGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG---EKGENGDVGPMGP 1181
             G  G+ G  G +G+ G++G +GA G  G  G  G  G PG PG    KGE G+ G  G 
Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669

Query: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG------------EAGNPGPPGE 1229
             G PG  G  GP G  G  G PG  G  G  GE+G PG             AG PGPPG 
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS 2729

Query: 1230 AGVGGPKGERGEKGEAGPPG-----AAGPPGA------KGPPGDDGPKGNPGPVGFPGD 1277
             G  GP+G +G+KGE GPPG     A G PGA      +G PG  GP+G  G      D
Sbjct: 2730 VGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  512 bits (1319), Expect = e-144
 Identities = 307/694 (44%), Positives = 356/694 (51%), Gaps = 106/694 (15%)

Query: 924  PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGP 983
            P P  V  P+G  GE G +G RG  GPPG PG  G  GA G +G  G    +G  G  G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA 1303

Query: 984  AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP-GPQG 1042
             G  G PG  G PG  GAPGLKG  G    PGP G PGERG  G  G  G PG+  G +G
Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGL---PGPRGDPGERGPRGPKGEPGAPGQVIGGEG 1360

Query: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGE--DGDKGEIGEPGQKG- 1099
            P       G PG KG  GP+G  G +GP+G PGP GP G PG    GDKG+ GE G  G 
Sbjct: 1361 P-------GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP 1413

Query: 1100 -----SKGDKGENGPPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFP 1152
                 + G+ G  G PG PG QGPVG PG  G  GD E G  G  G  G  G++G RG P
Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1212
            G  GP G +G PGP GE GE G+ GP GP G  G  G  G  GA GP+GPPG  G  G  
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG-- 1531

Query: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG-----DDGPKG 1267
             EKGEPG  G+P   G A V GPKGE+G+ G AGP GA G  G +GPPG     D GPKG
Sbjct: 1532 -EKGEPGRPGDPAVVGPA-VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589

Query: 1268 NPG---PVGF------------------PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1306
            +PG   P+G                   PG PGPPG  GP G+DG  G+KG++G PG PG
Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649

Query: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK-- 1364
             PG +GE G  G PG RGP G  G +G  GE G  G  G+ GP G  G  GP GP G+  
Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLV 1709

Query: 1365 -----------PGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKGDPGSK 1410
                       PG  G  G  GP G+ GLPGA G+   +G  GP GP G PG++G  G K
Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEK 1769

Query: 1411 GEKGHPGLIG---------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1461
            G++G PGL G           GP G  G  G  G PG  G PG +G+ G+PGP+GP G P
Sbjct: 1770 GDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLP 1829

Query: 1462 GPPG------LPGPQGPKGNKGSTGPAGQKGDSGL------------------------P 1491
            G PG      L G  G  G+ G  G  G+KGDSG                         P
Sbjct: 1830 GKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPP 1889

Query: 1492 GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQAD 1525
            G PG  GPPG+    +P  +  K  R   G + +
Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGE 1923



 Score =  128 bits (322), Expect = 4e-29
 Identities = 80/194 (41%), Positives = 92/194 (47%), Gaps = 22/194 (11%)

Query: 1358 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1417
            P+G  G+PG  GLRG  GP G+ GLPG   + G PGP GPPG         +KGE+G PG
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPG---RTGAPGPQGPPG------SATAKGERGFPG 1302

Query: 1418 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477
              G  G PG  G  G  G PG +GSPG  G  G PG  GP GP G PG PG        G
Sbjct: 1303 ADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV-----IG 1357

Query: 1478 STGPA--GQKGDSGLPGPP------GSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDN 1529
              GP   G+KGD G  GPP      G PGP G    P   +   K  R   G     +  
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417

Query: 1530 ILDYSDGMEEIFGS 1543
            I     G+  + GS
Sbjct: 1418 IAPGEPGLPGLPGS 1431


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  920 bits (2378), Expect = 0.0
 Identities = 584/1379 (42%), Positives = 674/1379 (48%), Gaps = 281/1379 (20%)

Query: 380  HGAYGEKGQKGEPAVVE----PGML----VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGD 431
            HG  G+KG++G P +      PGM      +GPPG  G  G  G PG +G  GPPG  G 
Sbjct: 42   HGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGY 101

Query: 432  RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGP 491
             G PG PG+PG DG PGPPG    +P   G  G +GP                     GP
Sbjct: 102  PGNPGLPGIPGQDGPPGPPG----IPGCNGTKGERGPL--------------------GP 137

Query: 492  PGPMGLTGRPGPVGGPGSSGAKGE-------------------SGDPGPQGPRGVQGPPG 532
            PG  G  G PGP G PG  G  GE                    G PGP G  G+QGP G
Sbjct: 138  PGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVG 197

Query: 533  P---TGKPGKRGRPGADGGRGM-----PGEPGAKGDRGFDGLPGLPG-----DKGHRGER 579
            P   TG PG  G PG  G +G       G  G KGD+G  G PG+PG     +KG    +
Sbjct: 198  PPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATK 257

Query: 580  GPQGPPGPPGDDGM-----RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 634
            G +G  G PG  GM     +GE G+ GPRG PG+ G +G  G  G PG PG PG+ G  G
Sbjct: 258  GEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQG 317

Query: 635  PPGPKGNMGPQGEPG------PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP- 687
            P G KG  GP G PG      P G++G  G  G PGP+G  GP G  G  G+PG  GLP 
Sbjct: 318  PQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPV 377

Query: 688  -GADGPPGHPGKEGQSGEKGALGP--PGPQGPIGYPGPRGVKGADGVRGLK--------- 735
             G  G PG PG+ G+ G++G  G   PGP G  G PGP G  G  G  G           
Sbjct: 378  PGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPG 437

Query: 736  --GSKGEKGEDGFPGFKGDMGLKGDRGEVGQI----GPRGEDGPEGPKGRAGPTGDPGPS 789
              G +G  G  G PGF G++G KG +GE   I    G RG  GP+GP G  G  G PG  
Sbjct: 438  PPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAK 497

Query: 790  GQ---------AGEKGKLGVPGLPGYPGRQGP-------------KGSTGFPGFPGANGE 827
            G          AG  G  G PGL G PG +G              KG  GFPG PG  G 
Sbjct: 498  GDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGR 557

Query: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG--ERGPQGPQ 885
             G+ G  G PG  G +G  G  G +G RGP G  G  G+ G  GPPGPPG    GP G +
Sbjct: 558  AGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDK 617

Query: 886  GPVGFPG---------PKGPPG-------PPGKDGLPGHPG---QRGETGFQGKTGPPG- 925
            G  GFPG         PKG PG       PPG +GLPG PG    +G+ GF G  G PG 
Sbjct: 618  GQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGL 677

Query: 926  ---------PG-GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP- 974
                     PG G  GP GP G  G  G+ G PG PG PG  GLPG  G +G KG+PG  
Sbjct: 678  PGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVG 737

Query: 975  -QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPPGPVGSPGERGSAG 1027
              G+ G  G  G+ G PGE+G  G  G PG  G  GP      +G PGP G PG  GS G
Sbjct: 738  LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG 797

Query: 1028 TAG--PIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-----GVQGPVGLPGPAGPA 1080
              G  P G  G PG QGPPG +G  G  GEKG  G  G D     G +G  GLPG  G +
Sbjct: 798  VPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQS 857

Query: 1081 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--GD----GEPGPR 1134
            G PG  G +G  G PG  GSKG+ G  G PG PG  GPVGAPG+ G  GD    G  GPR
Sbjct: 858  GLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR 917

Query: 1135 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP------------- 1181
            G  G+ G KGD G  G PG    + +  + G  G++GE G +GP+G              
Sbjct: 918  GDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVP 977

Query: 1182 --------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG---PPGEA 1230
                    PG PGP+G  G +G  G  G PG  GSVGG+G  G PGE G PG   P G  
Sbjct: 978  GKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSP 1037

Query: 1231 GVGGPKGERGEKGEAGPPGAA-----------------GPPGAKGP---------PGDDG 1264
            G+ G KG +GEKG+AGPPG                   G PG KG          PG  G
Sbjct: 1038 GLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPG 1097

Query: 1265 PKGNPGPVGFPGDPGPPGEPGP---AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321
             KG+PG VG+PG PG PGE G     G DG+ G KGE G PG PGP GP+G+ G PG  G
Sbjct: 1098 LKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG 1157

Query: 1322 --------------KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
                           RG PG  GA+G +G KG  G  G  G PG  G  G QG  G PGP
Sbjct: 1158 IPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGP 1217

Query: 1368 EGLRGIP--------GPVGEQGLPGAAGQDGPPGPMGPPGLPGL---KGD---------P 1407
            +G  G+P        GP G++G  G  G  G PGPMGPPGLPG+   KGD         P
Sbjct: 1218 QGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAP 1277

Query: 1408 GSKGEKGHPGLIGL---------------IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP 1452
            G  G KG PG  G+               +GPPG  G +G +GLPG QG  G +GD G+P
Sbjct: 1278 GVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP 1337

Query: 1453 GPAGPLGPPGP----------PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
            G  G  GPPGP          PGLPGP+GP G KG  G  G KG  G+ G  G PGPPG
Sbjct: 1338 GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396



 Score =  915 bits (2366), Expect = 0.0
 Identities = 582/1390 (41%), Positives = 670/1390 (48%), Gaps = 260/1390 (18%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413
            P  PP ++   G P     T+ +    GA G  G  G P +  PG   +GPPGP G  G 
Sbjct: 71   PQGPPGQKGDTGEPGLPG-TKGTRGPPGASGYPGNPGLPGI--PGQ--DGPPGPPGIPGC 125

Query: 414  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFRYGG-DGSKG 467
             G  G +GP GPPG PG  G PG PGLPG  G PG      PG +L     + G  G+ G
Sbjct: 126  NGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPG 185

Query: 468  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG--DPGPQGPR 525
            P                   L+GP GP G TG PGP G PG  G KG+ G    GP+G +
Sbjct: 186  PP--------------GLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDK 231

Query: 526  GVQGPPGPTGKPGK-------------------------------RGRPGADGGRGMPGE 554
            G QG  GP G PG+                               +G PG  G RG PG+
Sbjct: 232  GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGK 291

Query: 555  PGAKGDRGFDGLPGLPGDKGHRGERGPQG------PPGPPGDDGMRGEDGEIGPRGLPGE 608
             G KG++G  G PG PG  G  G +GPQG      PPGPPG     G  GE G RG PG 
Sbjct: 292  DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGT 351

Query: 609  AGPRGLLGPRGTPGAPGQPG--------MAGVDGPPGPKGNMGPQGEPG-----PPGQQG 655
             GPRG  GP+G PG PGQPG         AG  G PG +G  G +G PG     P G+ G
Sbjct: 352  PGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDG 411

Query: 656  NPGPQGLPGPQGPIG-----------PPGEKGPQGKPGLAGL------------------ 686
             PGP G PGP G  G           PPG++GP G PG  G                   
Sbjct: 412  LPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICD 471

Query: 687  -------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS-- 737
                   PG  GPPG  G  GQ G KG  G PG  G  G PGP+G  G  G  G KG   
Sbjct: 472  IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531

Query: 738  --------KGEKGEDGFPGFKG------------DMGLKGDRGEVGQIGPRGEDGPEG-- 775
                    KG+KG+ GFPG  G              GL G +G  G +G +GE GP G  
Sbjct: 532  EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591

Query: 776  ----PKGRAGPTGDPG--PSGQAGEKGKLGVPGLPGYPGRQGPKGSTG------------ 817
                 +G  GP G PG  P+G  G+KG+ G PG PG PG  GPKG  G            
Sbjct: 592  GFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAE 651

Query: 818  ----FPGFPGANGEKGARGVAGKPGPRGQRG-----------PTGPRGSRGARGPTGKPG 862
                 PGFPG  G++G  G  G+PG  G++G           P GP+G  G  G  G PG
Sbjct: 652  GLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPG 711

Query: 863  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK-- 920
              G  G +G PG PG +G +G  G VG PG KG PG PG  G PG  G  G  G  G+  
Sbjct: 712  TPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHG 770

Query: 921  -TGPPGPGGVVGPQGPTGETGPIGERGHPG--PPG---PPGEQGLPGAAGKEGAKGDPGP 974
              GPPG  G+ G  GP G  G +G  G PG  PPG   PPG QG PG +G  G KG+ G 
Sbjct: 771  AIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830

Query: 975  QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034
             G  G D P G +G  G +GLPG  G  GL G  G QG PG  G PG +G  G  G  G 
Sbjct: 831  PGFPGLDMP-GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQ 889

Query: 1035 PGRPGPQGPPGPAGEKGA---PGEKGPQGPAGRDGVQGPVGLPGPAGPA---------GS 1082
            PG PGP G PG  GEKG    PG  GP+G  G  G +G VGLPG  G           G 
Sbjct: 890  PGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ 949

Query: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGP------PGLQGPVGAPGIAGGDGEPG---P 1133
             G+ G+KG+IG  G+KGS+GD G  G PG       PG  GP G PGI+G  G PG   P
Sbjct: 950  KGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGP 1009

Query: 1134 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP 1193
            +G  G  G  G  G +G PG PGP G  GLPG  G KGE G  GP G  G PG RG +G 
Sbjct: 1010 KGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPGLRGEKGD 1068

Query: 1194 NGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1253
             G  G  G PG  G  G +G  G PG  G  G PG  G  G  G  GEKG+ G PG  G 
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 1254 PGAKG---------PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-----GVGGDKGED 1299
            PG KG         P G  G KG PG  G PG  G  GEPG  G+      G  GDKG  
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 1300 GD------PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353
            G+       G PG PG  GE G  GPPG +G PG  G+ G   E G KG+ G +G PG  
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATE-GPKGDRGPQGQPGLP 1247

Query: 1354 GPVGPQGPAGKPGPEGLRG------------IPGPVGE---QGLPGAAGQDG-------- 1390
            G  GP GP G PG +G++G            +PGP G+   QG+PG  G  G        
Sbjct: 1248 GLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDM 1307

Query: 1391 ----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE----KGDRGLPGTQGS 1442
                 PG  GP GLPGL+G  G +G++G PG  GL GPPG  G     KG+ GLPG +G 
Sbjct: 1308 GPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367

Query: 1443 PGAKGDGGIPGPAGP------LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1496
            PG KG  G+PGP G       +G PGPPG+PG  G  G KG  GPAG  G  G PGPPG 
Sbjct: 1368 PGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGP 1427

Query: 1497 PGPPGEVIQP 1506
             G PG +  P
Sbjct: 1428 DGLPGSMGPP 1437



 Score =  895 bits (2312), Expect = 0.0
 Identities = 550/1240 (44%), Positives = 643/1240 (51%), Gaps = 161/1240 (12%)

Query: 364  PGVPAETDITETSINGHGAYGEKGQKGEPAVVE-PGMLVEGPPGPAGPAGIMGPPGLQGP 422
            PGVP +  + E         GEKGQKGEP     PG+  +G PG  GP G  G  G +G 
Sbjct: 240  PGVPGQAQVQEKG--DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297

Query: 423  TGPPGDPGDRGPPGRPGLPGADGL------PGPPGTMLML-PFRYGGD----GSKGPTIS 471
             G PG PG+ G PG  G  G  G       PGPPG ++   P    G+    G+ GP   
Sbjct: 298  KGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGP--- 354

Query: 472  AQEAQAQAILQQARIALRGPPGPMG---LTGRPGPVG--GPGSSGAKGESGDPGPQGPRG 526
                             RG PGP G   L G+PGP G   PG +GA G  G+ G +G RG
Sbjct: 355  -----------------RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRG 397

Query: 527  VQGP--PGPTGKPGKRGRPGADGGRGMPG--------EPGAKGDRGFDGLPGLPG----- 571
              G   PGP+G+ G  G PG+ G  G PG        +PG  GD+G  G+PG PG     
Sbjct: 398  FPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEI 457

Query: 572  -DKGHRGE----------RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620
             +KG +GE          RGP GP GPPG+ G  G+ G  G RGLPG  G  G+ GP+GT
Sbjct: 458  GEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGT 517

Query: 621  PGAPGQPGMAGVDGP-------PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 673
            PG  GQPG  G  G         G KG+ G  G+PG  G+ G+PG  G PG  GP G PG
Sbjct: 518  PGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG 577

Query: 674  E---KGPQGKPGLAGLPGA---DGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGPRGV 725
                KG +G PG  G PG+    GPPG PG    G  G+KG  G PG  G  G PGP+G 
Sbjct: 578  SVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGE 637

Query: 726  KG----------ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 775
             G          A+G+ G  G  G +G+ GFPG  G  GL G++G VGQ G  G  GP G
Sbjct: 638  PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPG 696

Query: 776  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP--------KGSTGFPGFPGANGE 827
            PKG  G  GD GP G  G  G  G+PG PG  G++G         KG  G PG PG  GE
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG--GDGPPG---PPGERGPQ 882
            KG+ GV G PG  G  GP G +G RG  GP G PG  G+ G  G GPPG   PPG +GP 
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 883  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 942
            G  GP G  G KG PG PG D +PG  G +G  G  G TG  G  G+ G QG  G  G  
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFP 875

Query: 943  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
            G +G  G  G PG+ G PG  G  G  G+ G  G  G  GP G  G  G++G  G  G P
Sbjct: 876  GSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKP 935

Query: 1003 G---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053
            G         +KG +G QG  G +G  GE+GS G  G  G+PG+ G  G PG  G KG P
Sbjct: 936  GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP 995

Query: 1054 GEKGPQGPAGRDGVQGPVG---LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110
            G  G  G  G  G +G VG   LPG  G  G PG  G +G  G PG KG+KG+KG+ GPP
Sbjct: 996  GISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPP 1055

Query: 1111 GP--PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168
            G   PGL+G  G  GIAG  G PG +G++G  G  G  G+ G  G PG +G  G PG PG
Sbjct: 1056 GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG 1115

Query: 1169 EKGENGDVGPMGPPGPPGPRG---PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN-- 1223
            EKG+ G  G  G PG  G  G     GP G  G +G PGS G  G  GEKGEPG  G   
Sbjct: 1116 EKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGF 1175

Query: 1224 PGPPGEAGVGGPKGE---------------RGEKGEAGPPGAAGPPGAKGPPGD--DGPK 1266
            PG PG  G  G KGE               +GE+G  GPPG  G PG  G PG   +GPK
Sbjct: 1176 PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPK 1235

Query: 1267 GNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKR 1323
            G+ GP G    PG PGP G PG  G DGV GDKG  G PG PG PGP G+ G  G PG  
Sbjct: 1236 GDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIG 1295

Query: 1324 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1383
            G PG  G++G  G  G  G  G +G PG  G  G QG  G PG +GL G PGP G   + 
Sbjct: 1296 GSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDI- 1354

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443
               G+ G PGP GPPGL GL+G PG KG++G  GL+G+ GPP         G+PG  G+P
Sbjct: 1355 -IKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP---------GIPGFDGAP 1404

Query: 1444 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG 1483
            G KG+       GP GP GP G PGP GP G  GS GP G
Sbjct: 1405 GQKGE------MGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438



 Score =  816 bits (2107), Expect = 0.0
 Identities = 502/1140 (44%), Positives = 582/1140 (51%), Gaps = 161/1140 (14%)

Query: 499  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 558
            G  G  G  G  G +G  G PG QGP G QGPPG  G  G+ G PG  G RG    PGA 
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG---PPGAS 99

Query: 559  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD------DGMRGEDGEIGPRGLPGEA--- 609
            G  G  GLPG+PG  G            PPG       +G +GE G +GP GLPG A   
Sbjct: 100  GYPGNPGLPGIPGQDG------------PPGPPGIPGCNGTKGERGPLGPPGLPGFAGNP 147

Query: 610  GPRGLLGPRGTPG----------APGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 659
            GP GL G +G PG            G+ G  G+ G PGP G  G QG  GPPG  G PGP
Sbjct: 148  GPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGP 207

Query: 660  QGLPGPQGP--------IGPPGEKGPQGKPGLAGLPG-----ADGPPGHPGKEGQSGEKG 706
             G PGP G          GP G+KG QG  G  G+PG       G     G++GQ GE G
Sbjct: 208  PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267

Query: 707  ALGPP--GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764
              G P  G +G  G PGPRG  G DG +G KGS G  GE G+PG  G  G +G++GE G 
Sbjct: 268  FQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 765  IGPRG---EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 821
             GP G     GP G KG  G  G PGP G+ G KG  G+PG PG PG   P G  G PGF
Sbjct: 328  PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP-GQAGAPGF 386

Query: 822  PGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARGPTG--------KPGPKGTSGGDG 871
            PG  GEKG RG  G   PGP G+ G  GP GS G  G  G        +PGP G  G  G
Sbjct: 387  PGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG 446

Query: 872  PPGPP---GERGPQGPQGPV-------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK- 920
             PG P   GE G +G +G         G+ GP GP GPPG+ G PG PG +G+ G  G+ 
Sbjct: 447  IPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRD 506

Query: 921  --TGPPGPGGVVGPQGPTGETGPIGE-------RGHPGPPGPPGEQGLPGAAGKEGAKGD 971
               G PGP G  G  G  G  G  GE       +G  G PG PG+ G+ G AG  G  G 
Sbjct: 507  GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566

Query: 972  PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP--GPVGSPGERGSAGTA 1029
            PG  G  G  G  GL+   GERG PG  G PG +G  GP GPP  GP G  G++G AG  
Sbjct: 567  PGLPGPKGSPGSVGLK---GERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFP 623

Query: 1030 GPIGLPGRPGPQ----------GPPGPAGEKGAPGEKGPQGPAGRDGVQG---------- 1069
            G  G PG PGP+          GPPG  G  G+PG  GPQG  G  G  G          
Sbjct: 624  GGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGA 683

Query: 1070 ----PVGLPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGP--PGLQG 1117
                 +G PGP GP G  G  GD G  G PG+       G+ G +G+ G PG   PGL+G
Sbjct: 684  VGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKG 743

Query: 1118 PVGAPGIAGGDGE------PGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLP--GP 1166
              G PGI G  GE      PG  G+ G  G  G +G RG PGP   PG +G  G+P  GP
Sbjct: 744  LPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGP 803

Query: 1167 PGEKGENGDVGPMGPPGPPGPRGPQ-----------GPNGADGPQGPPGSVGSVG--GV- 1212
            PG +G  G  GP G  GPPG +G +           GP G  G QG PG  G  G  G+ 
Sbjct: 804  PGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLP 863

Query: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272
            G++G PG  G PG  GE GV G  G+ G  G  G PG  G  G  G PG  GP+G+PG  
Sbjct: 864  GQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923

Query: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1332
            G  GD G PG+PG   +  +G  KG+ GD G+ G  GP GE G  G PG  G PG  G  
Sbjct: 924  GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA 983

Query: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPA------GKPGPEGLRGIPGPVGEQGLPGAA 1386
            G+ G+ G KG+ G  G PG  G  GP+G        G PG +G+ GIPGP G  GLPG  
Sbjct: 984  GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 1387 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446
            G  G  G  GPPG+    G PG +GEKG  G+ G  G PGE+GEKG  G+PG  GSPG K
Sbjct: 1044 GAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLK 1099

Query: 1447 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            G        G +G PG PGLPG +G KG  G  G  G KG++GLPG PG  GP G+  +P
Sbjct: 1100 GS------PGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEP 1153



 Score =  792 bits (2045), Expect = 0.0
 Identities = 512/1195 (42%), Positives = 581/1195 (48%), Gaps = 171/1195 (14%)

Query: 336  DGDLGEYDFYEYKEYEDKP-----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKG 390
            DGD GE     +      P       P  E+   G P    I    + G G  GEKG++G
Sbjct: 292  DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI----VIGTGPLGEKGERG 347

Query: 391  EPAVVEPGMLVEGPPGPAGPAGIMGPPG-----LQGPTGPPGDPGDRG------------ 433
             P    P     G PGP G  G+ G PG     + G  G PG PG+RG            
Sbjct: 348  YPGTPGP----RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSL 403

Query: 434  --PPGRPGLPGADGLPGPPG----TMLMLPFRYGGDGSKGPT-----------ISAQEAQ 476
              P GR GLPG  G PGPPG    T  ++  + G  G +GP            I  +  +
Sbjct: 404  PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQK 463

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP---PGP 533
             ++ L       RGPPGP G    PG +G PG  GAKG+ G PG  G  GV GP   PG 
Sbjct: 464  GESCLICDIDGYRGPPGPQG---PPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGL 520

Query: 534  TGKPGKRGRPGA----------DGGRGMPGEPGAKGDRGF---DGLPGLPGDKGHRGERG 580
             G+PG +G PG            G  G PG+PG  G  G    DG PGLPG KG  G  G
Sbjct: 521  IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVG 580

Query: 581  PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 640
             +G  GPPG  G  G  G+ GP G PG  GP G +G +G  G PG PG  G+ GP G  G
Sbjct: 581  LKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 641  NMGPQGEPGPPGQQGNPGPQGLPGPQGPIG---------PPGEKGPQGKPGLAGLPGADG 691
             + P   PGPPG +G PG  G PGPQG  G          PGEKG  G+PG+ G PG  G
Sbjct: 640  KIVPL--PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPG 696

Query: 692  PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR--GLKGSKGEKGEDGFPGF 749
            P G  G  G  G  G  G PG  G  G PG +G KG  GV   GLKG  G  G  G PG 
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 750  KGDMGLKGDRGEVGQIGP------RGEDGPEGPKGRAGPTGDPG--PSGQAGEKGKLGVP 801
            KG +G+ G  GE G IGP      RGE GP G  G  G  G PG  P G  G  G  G P
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 802  GLPGYPGRQGPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859
            GL G PG +G KG  GFPG   PG  G+KGA+G+   PG  GQ G  G  G +GA G  G
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL---PGITGQSGLPGLPGQQGAPGIPG 873

Query: 860  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 919
             PG KG  G  G PG PG  GP G  G    PG KG  G PG  G  G PG +G+ G  G
Sbjct: 874  FPGSKGEMGVMGTPGQPGSPGPVGAPG---LPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930

Query: 920  KTGPPGP---------GGVVGPQGPTGETGPIGE---RGHPGPPGPPGEQGLPGAAGKEG 967
              G PG           G  G QG  G+ GPIGE   RG PG PG PG+ G  G  G+ G
Sbjct: 931  LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990

Query: 968  AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1027
             KGDPG  G  G  G  G +G  G  GLPG  G  G+ G  GPQG PG  G  G +G  G
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050

Query: 1028 TAGP--IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL---PGPAGPAGS 1082
             AGP  IG+PG  G +G  G AG  G+PGEKG +G  G  G+ G  GL   PG  G  GS
Sbjct: 1051 QAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGS 1110

Query: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG---- 1138
            PG  G+KG+ G PG  G  G KGE G PG PG  GP G  G  G DG PG  G++G    
Sbjct: 1111 PGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGL 1170

Query: 1139 -------MFGQKGDEGARG---------------------FPGPPGPIGLQGLPGPPGE- 1169
                     G KGD+G++G                     F GPPGP G  GLPG PG  
Sbjct: 1171 PGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHA 1230

Query: 1170 -KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228
             +G  GD GP G PG PG  GP GP G  G  G  G  G+ G  G  G PG  G+PG  G
Sbjct: 1231 TEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG 1290

Query: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288
              G+GG  G  G KG+ GPPG  G  G KG PG  G KG+ G  G PG  G PG PGP G
Sbjct: 1291 MPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPG 1350

Query: 1289 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348
               +       G+PG PGP GP G  G  G PG +G  G  G  G  G  G  G  GA G
Sbjct: 1351 PYDI-----IKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPG 1405

Query: 1349 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
              G+ GP GP GP G PGP      PGP            DG PG MGPPG P +
Sbjct: 1406 QKGEMGPAGPTGPRGFPGP------PGP------------DGLPGSMGPPGTPSV 1442



 Score =  677 bits (1746), Expect = 0.0
 Identities = 417/947 (44%), Positives = 479/947 (50%), Gaps = 93/947 (9%)

Query: 332  DLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE 391
            DL + GD G+  F        +  SP  +   PG+P             G+ G KG++G 
Sbjct: 536  DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH-PGLPGPK-------GSPGSVGLKGERGP 587

Query: 392  PAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 451
            P  V       G PG  G  G  GPPG  GP GP GD G  G PG PG PG  G  G PG
Sbjct: 588  PGGV-------GFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 452  TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSG 511
             ++ LP   G +G  G                      GP G  G  G PG  G PG  G
Sbjct: 640  KIVPLPGPPGAEGLPGSP-----------------GFPGPQGDRGFPGTPGRPGLPGEKG 682

Query: 512  AKGESGD--PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG-----FD 564
            A G+ G   PGP GP+GV G PG  G PG  GRPG +G  G PG  G KG+ G       
Sbjct: 683  AVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLK 742

Query: 565  GLPGLPGDKGHRGERGPQGPPGPPGDDG------MRGEDGEIGPRGLPGEAGPRGL--LG 616
            GLPGLPG  G  GE+G  G PG PG+ G      ++G  GE GP GLPG  G  G+  +G
Sbjct: 743  GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIG 802

Query: 617  PRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG--PPGQQGNPGPQGLPGPQGPIGPPGE 674
            P G  G PG  G  G+ GPPG KG  G  G PG   PG +G+ G QGLPG  G  G PG 
Sbjct: 803  PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGL 862

Query: 675  KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGL 734
             G QG PG+ G PG+ G  G  G  GQ G  G +G PG  G     G  G  G+ G RG 
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGE---KGDHGFPGSSGPRGD 919

Query: 735  KGSKGEKGEDGFPGFKGDM---------GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785
             G KG+KG+ G PG  G M         G KGD+GE GQIGP GE G  G  G  G  G 
Sbjct: 920  PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGK 979

Query: 786  PGPSGQAGEKGKLGVPGL---PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842
             G +GQ G+ G  G PG+   PG PG  GPKGS G  G PG  GEKG  G+   PGP+G 
Sbjct: 980  DGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI---PGPQGS 1036

Query: 843  RGPTGPRGSRGARGPTGKPG--------PKGTSGGDGPPGPPGERGPQGPQGPVGFPGP- 893
             G  G +G++G +G  G PG         KG  G  G PG PGE+G +G  G  G PG  
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 894  --KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP- 950
              KG PG  G  G PG PG++G+ G  G  G PG  G  G  G  G TGP G++G PG  
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSD 1156

Query: 951  --PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008
              PG  GE+G PG  G+ G  G PG +G  G  G  G  G  G  G+PG++G  G  G  
Sbjct: 1157 GIPGSAGEKGEPGLPGR-GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPP 1215

Query: 1009 GPQGPPGPVGSPGE-----RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063
            GPQG PG  GSPG      +G  G  G  GLPG PGP GPPG  G  G  G+KG  G  G
Sbjct: 1216 GPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPG 1275

Query: 1064 RDGVQGPVGLPG---PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120
              GV GP G PG     G  GSPG  G KG++G PG  G +G KG  G  G  G QG  G
Sbjct: 1276 APGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQG 1335

Query: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1180
             PG  G  G PGP G   +   KG+ G  G  GPPG  GLQGLPGP G++G  G VG  G
Sbjct: 1336 VPGAKGLPGPPGPPGPYDII--KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPG 1393

Query: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1227
            PPG PG  G  G  G  GP GP G  G  G  G  G PG  G PG P
Sbjct: 1394 PPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score =  630 bits (1625), Expect = e-180
 Identities = 408/932 (43%), Positives = 458/932 (49%), Gaps = 127/932 (13%)

Query: 736  GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 795
            G KG+KGE G PG +G +G  G +G      P G  GP G KG  G  G PG  G  G  
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQG------PEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 796  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 855
            G  G PG PG PG  G  G  G PG PG NG KG RG  G PG  G  G  GP G  G +
Sbjct: 97   GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 856  GPTGK----------PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905
            G  G+           G +G  G  G PGPPG  G QGP GP GF GP GPPGPPG    
Sbjct: 157  GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP--- 213

Query: 906  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG-----ETGPIGERGHPGPPGPPGEQGLP 960
            PG  GQ G   FQG  G  G  GV GP G  G     E G    +G  G  G PG QG+P
Sbjct: 214  PGEKGQMG-LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMP 272

Query: 961  GAAGKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGA---QGAPGLKGGEGPQGPP 1014
            G  G++G  G PGP+G  GKDG  G +G   FPGE G PG    QG  G KG  GP GPP
Sbjct: 273  GV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331

Query: 1015 G------PVGSPGERGSAGTAGPIG---------LPGRPGPQG--PPGPAGEKGAPGEKG 1057
            G      P+G  GERG  GT GP G         LPG+PGP G   PG AG  G PGE+G
Sbjct: 332  GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391

Query: 1058 PQG-----------PAGRDGVQGPVGLPGPAGPAG--------SPGEDGDKGEIGEPGQK 1098
             +G           P+GRDG+ GP G PGP G  G         PG  GD+G  G PGQ 
Sbjct: 392  EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451

Query: 1099 G------SKGDKGEN-------GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1145
            G       KG KGE+       G  GPPG QGP   PG  G  G+PG +G +G+ G+ G 
Sbjct: 452  GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGP---PGEIGFPGQPGAKGDRGLPGRDGV 508

Query: 1146 EGARGFPGPPGPIGLQGLPGPPGE-------KGENGDVGPMGPPGPPGPRGPQGPNGADG 1198
             G  G  G PG IG  G  G PGE       KG+ GD G  G PG  G  G  G +G  G
Sbjct: 509  AGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPG 568

Query: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258
              GP GS GSVG  GE+G PG  G PG  G+ G  GP G  G  G  G  G AG PG  G
Sbjct: 569  LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPG 627

Query: 1259 PPGDDGPKGNPGP-VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317
             PG  GPKG PG  V  PG PG  G PG  G  G  GD+G  G PG+PG PG  G  G P
Sbjct: 628  SPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP 687

Query: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP--------EG 1369
            G  G  GPPG  G +G  G+ G  G  G  G  G  G  G QG  G+PG          G
Sbjct: 688  GI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPG 746

Query: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL--IGPPGE 1427
            L GIPG  GE+G  G  G  G  G +GPPGL G++G+PG  G  G  G  G+  IGPPG 
Sbjct: 747  LPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGA 806

Query: 1428 QGEKGDRGLPGTQGSPGAKGDGG--------IPGPAGP---------LGPPGPPGLPGPQ 1470
            +G  G +G PG  G PG KG+ G        +PGP G           G  G PGLPG Q
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866

Query: 1471 GPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNI 1530
            G  G  G  G  G+ G  G PG PGSPGP G      P L  +K      G      D  
Sbjct: 867  GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG-----APGLPGEKGDHGFPGSSGPRGDPG 921

Query: 1531 LDYSDGMEEIFGSLNSL-KQDIEHMKFPMGTQ 1561
            L    G   + G   S+ K D+  MK   G Q
Sbjct: 922  LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953



 Score =  605 bits (1561), Expect = e-173
 Identities = 374/833 (44%), Positives = 433/833 (51%), Gaps = 97/833 (11%)

Query: 357  PPNEEFGPGVPA----ETDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 411
            PP  E  PG P     + D       G  G  GEKG  G+P +        G PGP GP 
Sbjct: 647  PPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI--------GFPGPPGPK 698

Query: 412  GIMGPPGLQGPTGPPGDPGDRGPPGRPG-----------LPGADGLPGPPGTMLMLPFRY 460
            G+ G PG  GP G PG PG  G PG PG           LPG  GLPG PG    +P   
Sbjct: 699  GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPG----IPGTP 754

Query: 461  GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG--D 518
            G  GS G  +     +  AI         GPPG  G+ G PGP G PGS G+ G  G   
Sbjct: 755  GEKGSIG--VPGVPGEHGAI---------GPPGLQGIRGEPGPPGLPGSVGSPGVPGIGP 803

Query: 519  PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 578
            PG +GP G QGPPG +G PG +G  G  G  G+   PG KGD+G  GLPG+ G  G  G 
Sbjct: 804  PGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGL 862

Query: 579  RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 638
             G QG PG PG  G +GE G +G  G PG  GP G  G  G  G  G PG +G  G PG 
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL 922

Query: 639  KGNMGPQGEPGPPGQQGN------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 692
            KG+ G  G PG PG           G +G  G +G IGP GEKG +G PG  G+PG DG 
Sbjct: 923  KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982

Query: 693  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 752
             G PG+ G  G+ G  G PG  G    PGP   KG+ G  GL G+ GEKG  G PG +G 
Sbjct: 983  AGQPGQPGPKGDPGISGTPGAPG---LPGP---KGSVGGMGLPGTPGEKGVPGIPGPQGS 1036

Query: 753  MGLKGDRG---EVGQIGPRGEDGP--EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807
             GL GD+G   E GQ GP G   P   G KG  G  G PG  G+ GEKG +G+PG+PG P
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 808  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867
            G +G  GS G+PG PG  GEKG +G+   PG  G  G  G  G  G  GPTG  G KG  
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGL---PGLDGIPGVKGEAGLPGTPGPTGPAGQKGEP 1153

Query: 868  GGDGPPGPPGERGPQG--PQGPVGFPGPKGPPGP------PGKDGLPGHPGQRGETGFQG 919
            G DG PG  GE+G  G   +G  GFPG KG  G       PG  G PG PG +GE GF G
Sbjct: 1154 GSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMG 1213

Query: 920  KTGPPGPGGVVGP-----QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974
              GP G  G+ G      +GP G+ GP G+ G PG PGP G  GLPG  G +G KG+PG 
Sbjct: 1214 PPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGW 1273

Query: 975  QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG------PVGSPGERGSAGT 1028
             G  G  GP   +G PG +G+PG  G+PG+ G +G  GPPG      P G PG +G  G 
Sbjct: 1274 PGAPGVPGP---KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 1029 AGPIGLPGR---PGPQGPPGP----AGEKGAPGEKGPQGPAGRDGVQGP------VGLPG 1075
             G  G+PG    PGP GPPGP     GE G PG +GP G  G  G+ GP       GL G
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390

Query: 1076 PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1128
              GP G PG DG  G+ GE G  G  G +G  GPPGP GL G +G PG    D
Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443



 Score =  558 bits (1437), Expect = e-158
 Identities = 340/735 (46%), Positives = 388/735 (52%), Gaps = 97/735 (13%)

Query: 850  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP---------VGFPGPKGPPGPP 900
            G     G  G+ G +G  G  G  G PG +GP+GPQGP          G PG KG  GPP
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 901  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960
            G  G PG+PG     G  G+ GPPGP G+ G  G  GE GP+      GPPG PG  G P
Sbjct: 97   GASGYPGNPGL---PGIPGQDGPPGPPGIPGCNGTKGERGPL------GPPGLPGFAGNP 147

Query: 961  GAAGKEGAKGDPGP-------QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
            G  G  G KGDPG          + G+ G  G+ G PG  GLPG QG  G  G  GP GP
Sbjct: 148  GPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGP 207

Query: 1014 PGPVGSPGERGSAGTA--GPIGLPGRPGPQGPPGPAG-----EKGAPGEKGPQGPAGRDG 1066
            PGP G PGE+G  G +  GP G  G  G  GPPG  G     EKG    KG +G  G  G
Sbjct: 208  PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267

Query: 1067 VQGPVGL-----PGPAGPAGSPGEDGDKGEIGEP------------GQKGSKGDKGENGP 1109
             QG  G+     PG  GP G PG+DGDKGE G P            G++G +G+KGE GP
Sbjct: 268  FQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 1110 PGPPGL---QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG-PI-GLQGLP 1164
            PGPPG+    GP+G  G  G  G PGPRG+    G KG  G  G PGPPG P+ G  G P
Sbjct: 328  PGPPGIVIGTGPLGEKGERGYPGTPGPRGEP---GPKGFPGLPGQPGPPGLPVPGQAGAP 384

Query: 1165 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGE--KGEPGEAG 1222
            G PGE+GE GD G  G    PGP G  G  G  G  GPPG  G   G+ E   G PG+ G
Sbjct: 385  GFPGERGEKGDRGFPG-TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443

Query: 1223 NPGPPGEAGVGGPKGERGEKGEA----------GPPGAAGPPGAKGPPGDDGPKGN---P 1269
             PG PG+ G  G  GE+G+KGE+          GPPG  GPPG  G PG  G KG+   P
Sbjct: 444  PPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLP 503

Query: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGD----------KGEDGDPGQPGPPGPSGEAGPP-- 1317
            G  G  G PGP G PG  GQ G  G+          KG+ GDPG PG PG +G AG P  
Sbjct: 504  GRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGR 563

Query: 1318 -GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGPEGLRGIP 1374
             G PG  GP G+ G+ G +GE+G  G  G  G  G TGP GP   GPAG  G +G  G P
Sbjct: 564  DGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFP 623

Query: 1375 GPVGEQGLPGAAGQDGP----PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1430
            G  G  GLPG  G+ G     PGP G  GLPG  G PG +G++G PG  G  G PGE+G 
Sbjct: 624  GGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGA 683

Query: 1431 KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGPKGNKGSTGPAGQKGD 1487
             G  G+ G  G PG KG  G+PG  GP G PG P   GLPG  G +G KG  G  G  G 
Sbjct: 684  VGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGL 741

Query: 1488 SGLPGPPGSPGPPGE 1502
             GLPG PG PG PGE
Sbjct: 742  KGLPGLPGIPGTPGE 756



 Score =  465 bits (1196), Expect = e-130
 Identities = 289/627 (46%), Positives = 320/627 (51%), Gaps = 97/627 (15%)

Query: 965  KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA---PGLKGGEGPQGPP---GPVG 1018
            +  AKG     G  GK    G++G  GERGLPG QG    PG++G EGPQGPP   G  G
Sbjct: 24   RAAAKGGCAGSGC-GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTG 82

Query: 1019 SPGERGSAGTAGP---------IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069
             PG  G+ GT GP          GLPG PG  GPPGP G  G  G KG +GP       G
Sbjct: 83   EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPL------G 136

Query: 1070 PVGLPGPAGPAGSPGEDGDKGEIGE----------PGQKGSKGDKGENGPPGPPGLQGPV 1119
            P GLPG AG  G PG  G KG+ GE           G++G  G  G  GPPG PGLQGPV
Sbjct: 137  PPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPV 196

Query: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG--------EKG 1171
            G PG  G  G PGP G  G  GQ G      F GP G  G QG+ GPPG        EKG
Sbjct: 197  GPPGFTGPPGPPGPPGPPGEKGQMG----LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKG 252

Query: 1172 ENGDVGPMGPPGPPGPRGPQ--GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
            +    G  G  G PG +G    G  G  G  GP G  G  G  GEKG PG  G PG PG 
Sbjct: 253  DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGL 312

Query: 1230 AGVGGPKGERGEKGEAGPPG---AAGPPGAKGP---PGDDGPKGNPGPVGF---PGDPGP 1280
             G  GP+GE+GE G  GPPG     GP G KG    PG  GP+G PGP GF   PG PGP
Sbjct: 313  IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372

Query: 1281 PG--EPGPAGQDGVGGDKGEDGDPGQPGP--PGPSGEAGPPGPPGKRGPPGAAG-----A 1331
            PG   PG AG  G  G++GE GD G PG   PGPSG  G PGPPG  GPPG  G      
Sbjct: 373  PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432

Query: 1332 EGRQGEKGAKGEAGAEGPPGKTGPV-------------------GPQGPAGKPGPEGLRG 1372
            E + G  G +G  G  G PG  G +                   GP GP G PG  G  G
Sbjct: 433  ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492

Query: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGL---PGLKGDP----------GSKGEKGHPGLI 1419
             PG  G++GLPG  G  G PGP G PGL   PG KG+P          G KG+ G PG  
Sbjct: 493  QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQP 552

Query: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479
            G+ G  G  G  G  GLPG +GSPG+ G  G  GP G +G PG  G  GP GP G  G  
Sbjct: 553  GMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG-YGPA 611

Query: 1480 GPAGQKGDSGLPGPPGSPGPPGEVIQP 1506
            GP G KG +G PG PGSPG PG   +P
Sbjct: 612  GPIGDKGQAGFPGGPGSPGLPGPKGEP 638


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  913 bits (2359), Expect = 0.0
 Identities = 543/1302 (41%), Positives = 675/1302 (51%), Gaps = 122/1302 (9%)

Query: 511  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL-PG- 568
            G KG++G PGP GP G+   PGP+GK G RG PG  G  G+PG PG KG +G  G  PG 
Sbjct: 489  GPKGDTGPPGPPGPAGI---PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545

Query: 569  -LPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQP 627
             +PG+KG +G  G  GPPG  GD G++G     G  GLPGE G  G  G  G+PG PG+ 
Sbjct: 546  PVPGEKGDQGLSGLMGPPGMQGDKGLKGHP---GLPGLPGEQGIPGFAGNIGSPGYPGRQ 602

Query: 628  GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---------GPQGPIGPPGEKGPQ 678
            G+AG +G PGPKG  G  G PG  GQ G  G +G+P         G QG  G  G++GP 
Sbjct: 603  GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662

Query: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738
            G  G  GL G  GPPG PG       +G++GP GP GP G PGP G+ G    +GL G K
Sbjct: 663  GLDGSPGLVGGTGPPGFPGL------RGSVGPVGPIGPAGIPGPMGLSGN---KGLPGIK 713

Query: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798
            G+KGE G  G  G+ G  GD+G VG  GP G  G  GP G+   TGDPG  G +G  G  
Sbjct: 714  GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ---TGDPGLQGPSGPPGPE 770

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 858
            G PG  G PG+ GP+G  G  G  G  G  G +G  G+ GP G  G  GPRG  G +G  
Sbjct: 771  GFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830

Query: 859  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918
            G+PGP+G  G  G  G  G+ G  GP G  G  G  G  G  G+ G PG  G +GE G  
Sbjct: 831  GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890

Query: 919  GKTGPPGPGGVVGP---------QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 969
            G  GPPG  G +GP         +GP G  GP G+RG  GP G  GEQG+ GA G++G +
Sbjct: 891  GYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQ 950

Query: 970  GDPGPQGISGKDGPAGLRGF---PGERGLPGA------QGAPGLKGGEGPQGPPGPVGSP 1020
            G  GP G+ GK G  G RGF   PG +GLPG+       G PGL+G +G  GPPG +G  
Sbjct: 951  GKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME 1010

Query: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1080
            G  G+ G +G  G PG  G  G  G  G  G PG +G  G  G +G+QG  GL G  G  
Sbjct: 1011 GPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGR 1070

Query: 1081 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP---GLQGPVGAPGIAGGDGEPGP---- 1133
            G PGEDG+KGE+G PG  G  G  G+ G PGP    G+ G  G PG  G  G+ GP    
Sbjct: 1071 GLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEV 1130

Query: 1134 --RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1191
              RG  G  G+ G +GARG  G  G +GL G  G PG  G  G  G  GP G PGP+G +
Sbjct: 1131 GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190

Query: 1192 GPNGAD----GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGP 1247
            G  G D    GP GP G  G VG  GE+GEPG  G  G  G  G+ G  G++G  GE G 
Sbjct: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD 1250

Query: 1248 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307
             G  G  G +G  G+ G KG PGP G PG PG  G  GP G  G  G  G  G+PG+ GP
Sbjct: 1251 QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGP 1310

Query: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
            PG        G PG RG PG  G  G  G  G KG +G  G PG  GP G QG  G+PG 
Sbjct: 1311 PGKQ------GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGI 1364

Query: 1368 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1427
            +G RG  G  G+QG  G  G  G PG  G  GL G +G PG KG +G  G++G+ GP G 
Sbjct: 1365 QGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGP 1424

Query: 1428 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1487
             G +G+ G  G +         GI GP G  GP G  G  G  GP+G +G  GP      
Sbjct: 1425 IGHRGNTGPLGRE---------GIIGPTGRTGPRGEKGFRGETGPQGPRGQPGP------ 1469

Query: 1488 SGLPGPPGSPGP--PGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLN 1545
               PGPPG+PGP    ++   +  L    T    E  Q + +  ++D+S   EEIF +LN
Sbjct: 1470 ---PGPPGAPGPRKQMDINAAIQALIESNTALQMESYQ-NTEVTLIDHS---EEIFKTLN 1522

Query: 1546 SLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSG 1605
             L   +  +K P+GT+ NPAR CKDL        DG+YWIDPN GC  D+ +V+CNF++G
Sbjct: 1523 YLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAG 1582

Query: 1606 GETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTA 1665
            G+TC+ P   ++                 EF  GK              VQM FL LL++
Sbjct: 1583 GQTCLPPVSVTK----------------LEFGVGK--------------VQMNFLHLLSS 1612

Query: 1666 SARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-Y 1724
             A    T HC  +  W    +      + F G N +    +     K L D C  + G +
Sbjct: 1613 EATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSW 1672

Query: 1725 EKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1766
             K     +T + +Q+P+++V         +K+  +   VCFL
Sbjct: 1673 HKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714



 Score =  733 bits (1892), Expect = 0.0
 Identities = 440/1035 (42%), Positives = 521/1035 (50%), Gaps = 81/1035 (7%)

Query: 341  EYDFYEYKEYEDKPT--------SPPNEEFGPGVPAETDITETS-------INGH----- 380
            E + Y+Y  YED  T         P  +   PG P    I   S       I G      
Sbjct: 466  ETELYDYYYYEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPG 525

Query: 381  --GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP--------- 429
              G  G KG KG+P    PG  V G  G  G +G+MGPPG+QG  G  G P         
Sbjct: 526  LPGLPGPKGPKGDPGF-SPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584

Query: 430  ---------GDRGPPGRPGLPGADGLPGPPGTMLML-----PFRYGGDGSKG-PTISAQE 474
                     G  G PGR GL G +G PGP G    +       + G +G +G P I  ++
Sbjct: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644

Query: 475  AQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT 534
                   +Q      G  GP GL G PG VGG G  G  G  G  GP GP G  G PGP 
Sbjct: 645  GFKG---RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPM 701

Query: 535  GKPGKRGRPGADGGRGMP------GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP--- 585
            G  G +G PG  G +G        GEPG  GD+G  GLPG PG +G  G  G  G P   
Sbjct: 702  GLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQ 761

Query: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645
            GP G  G  G  G+IG  G  G  GP+GLLG RG PG PG  G  G +GP G  G +GP+
Sbjct: 762  GPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPR 821

Query: 646  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
            G+PG  G  G PGP+GL   +G +G  G  G  G+ G  GLPG  G  G  G++G+ G  
Sbjct: 822  GKPGQKGYAGEPGPEGL---KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSP 878

Query: 706  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765
            G LGP G +G +GYPGP GV G  G  GL G  G +G  G  G KG  G +G  G +G+ 
Sbjct: 879  GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938

Query: 766  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 825
            G +G  G +G +G+ GP G  G +G  GE+G  G PGL G P      GSTG  G PG  
Sbjct: 939  GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLP------GSTGDRGLPGEP 992

Query: 826  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 885
            G +G +G  G PG  G  GP G  G  G +G  G  G  GT+G  G  G PG RG  G  
Sbjct: 993  GLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAP 1052

Query: 886  GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 945
            G  G  G  G  G PG  GLPG  G++GE G  G  GP G  G  G  GP G  G  G+R
Sbjct: 1053 GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112

Query: 946  GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLK 1005
            G    PG  G++G  G  G+ G++G PG  G SG  G  G RG  G  GL G  G PG+ 
Sbjct: 1113 GR---PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169

Query: 1006 GGEGPQGPPGPVGSPGERGSAGTAGPIG-LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1064
            G  G QG PGP G PG +G  G  G    + G PGP+G PGP G++G  GE G +G  G 
Sbjct: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229

Query: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGA 1121
             GV G  G  G  GP G PG+ G++G  GE G +G+KG KG  GP   PG PGLQG +G 
Sbjct: 1230 VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGP 1289

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
             GI G  G  G  G  G  G  G +G  G  G PG  GL G PGPPG KG +      G 
Sbjct: 1290 KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS------GL 1343

Query: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
            PG PG +GP+G  G  G  G  G  G  G  G++G  G+ G  G PGE GV G  G +G 
Sbjct: 1344 PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGF 1403

Query: 1242 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1301
             G  GP G AG  G  GP G  G +GN GP+G  G  GP G  GP G+ G  G+ G  G 
Sbjct: 1404 PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP 1463

Query: 1302 PGQPGPPGPSGEAGP 1316
             GQPGPPGP G  GP
Sbjct: 1464 RGQPGPPGPPGAPGP 1478



 Score =  731 bits (1886), Expect = 0.0
 Identities = 444/1022 (43%), Positives = 520/1022 (50%), Gaps = 95/1022 (9%)

Query: 403  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LMLPFRY 460
            GPPGP GPAGI GP G +GP G PG  G+   PG PGLPG  G  G PG      +P   
Sbjct: 495  GPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGFSPGQPVPGEK 551

Query: 461  GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 520
            G  G  G  +     Q    L+     L G PG  G+ G  G +G PG  G +G +G  G
Sbjct: 552  GDQGLSG-LMGPPGMQGDKGLK-GHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEG 609

Query: 521  PQGPRGVQG------------PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 568
              GP+G QG            P G  G PG RG+ G  G +G PG+ G +G  G DG PG
Sbjct: 610  NPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPG 669

Query: 569  L------PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 622
            L      PG  G RG  GP GP GP G  G  G  G  G  G+ G+ G +G  G  G PG
Sbjct: 670  LVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729

Query: 623  APGQPGMAGVDGPPGPKGNMGP---------QGEPGPPGQQGNPGPQGLPGPQGPIGPPG 673
             PG  G  G+ GPPG +G  GP         QG  GPPG +G PG  G+PG  GP GP  
Sbjct: 730  YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP-- 787

Query: 674  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 733
                       GL G  GPPG PG +G  GE+G +G  G  GP G PG +G  G  G  G
Sbjct: 788  ----------KGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837

Query: 734  LKGSKGEKGEDGFPGFKGDMGLKGD---RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 790
            LKG  G++G  G  G  G +GL G+    G +G+ G RG  GP GP+G  G  G PGP G
Sbjct: 838  LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897

Query: 791  QAGEKGKLGVP---GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP-- 845
              G  G LG+P   G  G PG QGPKG  G  G  G  GE+G +G  G+ G +G+RGP  
Sbjct: 898  VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957

Query: 846  ----TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901
                TG  G RG +G  G  G  G++G  G PG PG RG QG  GP G  G +GPPG  G
Sbjct: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEG 1017

Query: 902  KDGLPGHPGQRGETGFQGK---TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 958
            + GL G PG +G+ G  G    TG PG  G  G  G  G  G  G +G PG  G PGE G
Sbjct: 1018 ESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG 1077

Query: 959  LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG--GE-GPQGPPG 1015
              G  G  G  G  G  G +G  GP G+ G PG+RG PG +G  G  G  GE G +GPPG
Sbjct: 1078 EKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 1016 PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG--- 1072
             +G  G +G+ GT G +G  G  GP G PG  G +G  G+ GP G  G  G +G  G   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 1073 -LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131
             + GP GP G PG  GD+GE GEPG +G KG  G  G  G  G QGP G PG  G  G  
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPP------GPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1185
            G RG +G  G+KG  G  G PG P      GP G+QG  G  G  G  G +GP G  G P
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317

Query: 1186 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1245
            G RG  G  G  G  GPPG  GS G  G  G  G  G  G PG+ G+ G +G RG +G+ 
Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377

Query: 1246 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1305
            GP    G PG KG PG+ G +   G  GF G PGP G  G AG  G+ G KG  G  G  
Sbjct: 1378 GP---CGDPGLKGQPGEYGVQ---GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431

Query: 1306 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1365
            GP G  G  GP G  G R            GEKG +GE G +GP G+    GP GP G P
Sbjct: 1432 GPLGREGIIGPTGRTGPR------------GEKGFRGETGPQGPRGQP---GPPGPPGAP 1476

Query: 1366 GP 1367
            GP
Sbjct: 1477 GP 1478



 Score =  647 bits (1669), Expect = 0.0
 Identities = 375/805 (46%), Positives = 426/805 (52%), Gaps = 46/805 (5%)

Query: 734  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQA 792
            L+G KG+ G  G PG  G  G  G RG  G  GP G  G  G  G  GP GDPG S GQ 
Sbjct: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546

Query: 793  --GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK------PGPRGQRG 844
              GEKG  G+ GL G PG QG KG  G PG PG  GE+G  G AG       PG +G  G
Sbjct: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAG 606

Query: 845  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG 904
            P G  G +GA+G  G PG  G  G +G  G PG RG +G +G  GFPG  G  GP G DG
Sbjct: 607  PEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDG 666

Query: 905  LPGHPGQRGETGFQG------KTGPPGPGGVVGP------------QGPTGETGPIGERG 946
             PG  G  G  GF G        GP GP G+ GP            +G  GE G  GE G
Sbjct: 667  SPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELG 726

Query: 947  HPGPPGPPGEQGLPGAAG---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA---QG 1000
             PG PG  G  GLPG  G   K G  G  G  G+ G  GP G  GFPG+ G+PG    +G
Sbjct: 727  EPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEG 786

Query: 1001 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1060
              GL G  GP GPPG  G+ GE G  G  G +G  G+PG +G  G  G +G  GE G QG
Sbjct: 787  PKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQG 846

Query: 1061 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1120
              G+ G  GPVGLPG  G  GS GE   KGE G PG  G +G+KG  G PGPPG+ GP+G
Sbjct: 847  NIGKIGETGPVGLPGEVGMTGSIGE---KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG 903

Query: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1180
              G+ G  G  GP G QG  GQ+G  G      P G +G QG+ G  GEKG+ G  GP G
Sbjct: 904  PLGLPGHVGARGPPGSQGPKGQRGSRG------PDGLLGEQGIQGAKGEKGDQGKRGPHG 957

Query: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1240
              G  G  G +G  G  G QG PGS G  G  GE G  G  G+ GPPGE G+ GP G  G
Sbjct: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEG 1017

Query: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1300
            E G  G PGA G  G  G  G  G  G  G  G PG+ G  G+ G  G  G  G  GEDG
Sbjct: 1018 ESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG 1077

Query: 1301 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1360
            + G+ G PG  G  G  G  G  GP G  G  G++G  G KG+ G  GP G+ G  GP G
Sbjct: 1078 EKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG--- 1417
              GK GP+G RG  G VG  GL G  G+ G PG  G  G PG  G PG KGEKG+PG   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 1418 -LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1476
             ++G  GP GE G  GD+G  G  G+ G KG  G+PG  G  G  GPPG PG QG +G K
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 1477 GSTGPAGQKGDSGLPGPPGSPGPPG 1501
            G  G  G KG  G PGP G PG PG
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPG 1282



 Score =  344 bits (882), Expect = 5e-94
 Identities = 236/572 (41%), Positives = 276/572 (48%), Gaps = 76/572 (13%)

Query: 336  DGDLGEYDFYEYK-EYEDKPTSPPNEEFGP-GVPAETDIT-ETSING-HGAYGEKGQKGE 391
            DG LGE      K E  D+    P+   G  G P E     +  + G  G+ G++G  GE
Sbjct: 932  DGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991

Query: 392  PA-------VVEPG-MLVEGPPGPAGPAGIMGPPGLQGP---------TGPPGDPGDRGP 434
            P        V  PG M +EGPPG  G +G+ G PG +G          TG PG  G+ G 
Sbjct: 992  PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGA 1051

Query: 435  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494
            PG  GL G DGL G PG    LP   G DG KG     +      I    R    G PGP
Sbjct: 1052 PGEEGLQGKDGLKGVPGGR-GLP---GEDGEKG-----EMGLPGIIGPLGRSGQTGLPGP 1102

Query: 495  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA--------- 545
             G+ G PG  G PG  G KG+ G  G  G RG  G  G +G  G RG  GA         
Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162

Query: 546  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-------GPQGPPGPPGDDGMRGEDG 598
            DG  G+PG  G +G  G  GLPG  G+KG+ GE        GP+G PGP GD G RGE G
Sbjct: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPG 1222

Query: 599  EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPG 658
              G +G  G  G RG  G +G PG PG  G  G+ G  G +GN G +G PGP G+ G PG
Sbjct: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282

Query: 659  PQGLPGPQG---------------PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 703
             QGL GP+G                IGPPG+   QG PG+ G PG  G  G PG  G  G
Sbjct: 1283 LQGLLGPKGIQGYHGADGISGNPGKIGPPGK---QGLPGIRGGPGRTGLAGAPGPPGVKG 1339

Query: 704  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
              G  G PG QGP G  G  G  G  G RG +G++G++G  G PG KG  G  G +G  G
Sbjct: 1340 SSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTG 1399

Query: 764  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823
              G  G  GPEG  G  G +G  GP G  G  G LG  G+ G  GR GP+G         
Sbjct: 1400 FQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRG--------- 1450

Query: 824  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 855
               EKG RG  G  GPRGQ GP GP G+ G R
Sbjct: 1451 ---EKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  325 bits (832), Expect = 3e-88
 Identities = 196/439 (44%), Positives = 226/439 (51%), Gaps = 51/439 (11%)

Query: 1101 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160
            +G KG+ GPPGPPG   P G PG +G       RG +G+ G  G+ G  G PGP GP G 
Sbjct: 488  RGPKGDTGPPGPPG---PAGIPGPSG------KRGPRGIPGPHGNPGLPGLPGPKGPKGD 538

Query: 1161 QGL-PGPP--GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217
             G  PG P  GEKG+ G  G MGPPG  G +G +G  G  G  G  G  G  G +G  G 
Sbjct: 539  PGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598

Query: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277
            PG  G  GP G  G   PKG +G  G  G  G  GP G +G PG  G KG  G  GFPGD
Sbjct: 599  PGRQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGD 655

Query: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337
             G   + GPAG DG  G  G  G PG PG  G  G  GP GP G  GP G +G +G  G 
Sbjct: 656  FG---DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712

Query: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1397
            KG KGE G  G  G+ G  G +G  G PGP G+RG  GP G+ G PG  G  GPPG   P
Sbjct: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG---P 769

Query: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP---------GTQGSPGAKGD 1448
             G PG  G PG  G +G  GL+G  GPPG  G KG +G           G +G PG KG 
Sbjct: 770  EGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGY 829

Query: 1449 GGIPGP------------------AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1490
             G PGP                   GP+G PG  G+ G  G KG +GS GP G +G+ G+
Sbjct: 830  AGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV 889

Query: 1491 ---PGPPGSPGPPGEVIQP 1506
               PGPPG PGP G +  P
Sbjct: 890  MGYPGPPGVPGPIGPLGLP 908



 Score =  234 bits (597), Expect = 6e-61
 Identities = 154/383 (40%), Positives = 183/383 (47%), Gaps = 61/383 (15%)

Query: 358  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV----EPGMLVEGPPGPAGPAG- 412
            P  + G   P     T  ++   G  G  G+ G P       +PG    G PGP G  G 
Sbjct: 1135 PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGP--SGLPGPKGEKGY 1192

Query: 413  ------IMGPPGLQGPTGPPGDPGDRGPPGR---------PGLPGADGLPGPPGTMLMLP 457
                  ++GPPG +G  GP GD G+RG PG          PGL GA G  GPPG     P
Sbjct: 1193 PGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGE----P 1248

Query: 458  FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG------PVGGPGSSG 511
               G  G KG   S           +     +G PGP G  G PG      P G  G  G
Sbjct: 1249 GDQGEQGLKGERGS-----------EGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297

Query: 512  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGR------PGADGGRGMPGEPGAKGDRGFDG 565
            A G SG+PG  GP G QG PG  G PG+ G       PG  G  G+PG PG +G +G  G
Sbjct: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357

Query: 566  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 625
            LPG PG +G RG RG QG  GP GD G++G+         PGE G +GL G +G PG  G
Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ---------PGEYGVQGLTGFQGFPGPKG 1408

Query: 626  QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 685
              G AG+ G  GPKG +G +G  GP G++G  GP G  GP+G  G  GE GPQG     G
Sbjct: 1409 PEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP---RG 1465

Query: 686  LPGADGPPGHPGKEGQSGEKGAL 708
             PG  GPPG PG   Q     A+
Sbjct: 1466 QPGPPGPPGAPGPRKQMDINAAI 1488



 Score =  131 bits (329), Expect = 7e-30
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 29/196 (14%)

Query: 1368 EGLRGIPGPVGEQGLPGAAGQDGP---------PGPMGPPGLPGL------KGDPGSK-- 1410
            E LRG  G  G  G PG AG  GP         PGP G PGLPGL      KGDPG    
Sbjct: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544

Query: 1411 ----GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466
                GEKG  GL GL+GPPG QG+KG +G PG    PG  G+ GIPG AG +G PG PG 
Sbjct: 545  QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGR 601

Query: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1526
             G  GP+GN    GP G +G  G PG  G  GP GE  + +P +  KK  +  +G   D 
Sbjct: 602  QGLAGPEGN---PGPKGAQGFIGSPGEAGQLGPEGE--RGIPGIRGKKGFKGRQGFPGDF 656

Query: 1527 DDNILDYSDGMEEIFG 1542
             D      DG   + G
Sbjct: 657  GDRGPAGLDGSPGLVG 672



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 63/251 (25%), Positives = 110/251 (43%), Gaps = 37/251 (14%)

Query: 80  AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLF 139
           A +  P  ++ P     + F+IL  ++  +   +FL SI N++ +Q +GV++   P  L 
Sbjct: 88  AYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKLV 143

Query: 140 EDHTGK-PAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV 198
               GK PA  +Y      ++ D +WH  AI++  ++V+M V+C KK        E    
Sbjct: 144 VHIRGKQPAVFNY------SVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197

Query: 199 DTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQI 258
           D+N +   G+   +   FEG + Q  I    +A+ DYC +    C     + A   +P  
Sbjct: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQC-----RQADKYQP-- 250

Query: 259 DEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNP---VEEIFTEEYLT-GEDYDSQRK 314
                     E +        T+ P H      P P    E++ +E+  T G+   +  K
Sbjct: 251 ----------ETSIPCTTLIPTKIPEH-----SPPPKLFAEKVLSEDTFTEGKSIPNIIK 295

Query: 315 NSEDTLYENKE 325
           N  +T+Y+ +E
Sbjct: 296 NDSETVYKRQE 306


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  906 bits (2341), Expect = 0.0
 Identities = 572/1313 (43%), Positives = 650/1313 (49%), Gaps = 206/1313 (15%)

Query: 381  GAYGEKGQKGEPAVVEPGMLV----EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436
            G  GEKG+KG    +   +       G PG  G  G  G  G  GPTG PG+PG  GPPG
Sbjct: 164  GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPG 223

Query: 437  RPGLPGADGLPGPPGTMLML-PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP--- 492
            +PG PG  G PG      M  P   G  GS GPT+  +                 PP   
Sbjct: 224  QPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVE-----------------PPDFC 266

Query: 493  ---GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
               G  G+ G PG VG PG  G KGESG  G +G +G+ G PGP G PG  G PG  G  
Sbjct: 267  LYKGEKGIKGIPGMVGLPGPPGRKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPG-- 323

Query: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP-----------QGPPGPPGDDGMRGEDG 598
             + GE G  GD G  GL G  GD G+RG  GP           +GPPG PG  G  GE G
Sbjct: 324  -LKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG 382

Query: 599  EIGPRGLPGE--------AGPRGLLGPRGTPGAPGQPGMAGV----DGPPGPKGNMGPQG 646
            ++GP G PG         AG  G  GP+G PG PG PG AG+    D  PG  G  G  G
Sbjct: 383  DVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442

Query: 647  EPGPPGQQGNPGPQ------GLPGPQG---PIGPPGEKGPQGKPGLAGL----PGADGPP 693
             PG PG QG PG        G PGPQG    +GPPG +GP+G+ G  GL    PG  GPP
Sbjct: 443  LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPP 502

Query: 694  GHPGKEGQSGEKGALG------------PPGPQGPIGYPGPRGVKGADGVRG-------- 733
            G PG  G+ G KG LG            PPG +GP G PG  G  G  G +G        
Sbjct: 503  GPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVS 562

Query: 734  -LKGSKGEKGEDG---FPGFKGDMGLKGDRGEVGQIGPRGED-----------GPEGPKG 778
             +KG KGE+G DG   FPG  G  G  G  GE G  GP G+            GP GP G
Sbjct: 563  RVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPG 622

Query: 779  RAGPTGDPGPS--GQAGEKGKLGVPGLPG--------------------YPGRQGPKGST 816
            +AGP G PG    G  GE+G  GVPG PG                    YPGR GP G  
Sbjct: 623  KAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFD 682

Query: 817  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGTSGGD--G 871
            G PG  G  G +GA G++G  G +G+ G  G     G  G RG  G PG  G  G    G
Sbjct: 683  GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG 742

Query: 872  PPGPPGERGPQGPQGPVGFP--GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
            PPGPPG  G  G +G  G P  G  GPPG  G  G+PG  G RG+ G  G  GP G  G 
Sbjct: 743  PPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGF 802

Query: 930  VGPQGPTGETGPIGERGHPGPPGP---------PGEQGLPGAAGKEGAKGDPGPQGISGK 980
            +G +GP G  G  G  G PGPPG          PG+ GLPG  G  GA G  G  G  G 
Sbjct: 803  LGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP 862

Query: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPPGPVGS---------PGERGS 1025
             GPAG++G PG  G PGA G PGL G  GP       GPPGP G          PGERG 
Sbjct: 863  PGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK 922

Query: 1026 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV---GLPGPAGPAGS 1082
             G  G  G  G PG +G  G  G++G  G KG  GP G +G    +   G PG  GP G 
Sbjct: 923  PGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGD 982

Query: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPG----PPGLQGPVGAPGIAGGDGEPGPRGQQG 1138
             G  G++G+ G PG +G +G+ G  GPPG     PG +G  G PG  G  G  G RG  G
Sbjct: 983  DGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIG 1042

Query: 1139 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD-VGPMGPPGPPGPRGPQGPNGAD 1197
              G  GD+G  G PGPPG  G+ G  GP G KG+     GP GP G PG  G  G  GA 
Sbjct: 1043 FPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGAS 1102

Query: 1198 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
            G QG PG  G  G  G  G PG +G PG PG+ G+ G +G+ GE G+ GP G  G PG  
Sbjct: 1103 GEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIP 1162

Query: 1258 GPPGDDGPKGNPGPVGFPGDPGPPG--------EPGPAGQDGVGGDKGEDGDPGQPG--P 1307
            GPPG  GP G+PG  G  G  G  G        + GP G  G+ G KGE GDPG PG  P
Sbjct: 1163 GPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP 1222

Query: 1308 PGPSGEAGPPGPPGKRGPPGAAGAEGR-------------QGEKGAKGEAGAEGPPGKTG 1354
            PGP G+ GPPGPPG  GPPG AGA GR             QG  G  G  GA GPPG  G
Sbjct: 1223 PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPG 1282

Query: 1355 PV----GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1410
             V    G  G  G PGP G  G PGP G +G PG  G+DG  GP+G PG  G  G PG  
Sbjct: 1283 SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342

Query: 1411 GEKGHPGLIGLIGP---PGEQGEKGDR----------GLPGTQGSPGAKGDGGIPGPAGP 1457
            GEKG PG  G  GP   PG +GE G            GLPG  G  G +G  G+PG  GP
Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP 1402

Query: 1458 LGP--PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508
             GP   G PGL G +G  G  GS GP G+KGD+G  G PG PGPPG +  P P
Sbjct: 1403 SGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGP 1455



 Score =  896 bits (2315), Expect = 0.0
 Identities = 560/1328 (42%), Positives = 649/1328 (48%), Gaps = 224/1328 (16%)

Query: 385  EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPG---DPGDRGPPGRPGLP 441
            EKG +G P    P   + GP G  GP G+ G  G++G  GPPG   D GD+GP G PG P
Sbjct: 60   EKGSRGPPGPPGPQGPI-GPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP 118

Query: 442  GADGLPGPPGTM--LMLPFRYGGDGSKG-------------------PTISAQEAQAQAI 480
            G DG+PG PG       P   G +GS+G                   P    ++  +  I
Sbjct: 119  GLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFI 178

Query: 481  LQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPG-- 538
            L   +  ++G  G  GL G PG  G  G +G  G  G+PG  GP G  G PG  G PG  
Sbjct: 179  LGAVK-GIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVG 237

Query: 539  ---KRGRPGADGGRGMPG---------------EPGAKGDRGFDGLPGLPGDKGH----- 575
               + G PG  G +G PG               E G KG  G  GLPG PG KG      
Sbjct: 238  VKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGA 297

Query: 576  RGERGPQGPPGPPGDDGMRGEDGEIGPRG---LPGEAGPRGLLGPRGTPGAPGQPGMAGV 632
            +GE+G  G PGP GD G  G  G  G +G   L G+ G  GL+GP+G PG  G PG  GV
Sbjct: 298  KGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGV 357

Query: 633  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK--------GPQGKPGLA 684
               P P    GP G+PG PG+ G  G  G PGP G +G PGE         GPQG PGL 
Sbjct: 358  LVTP-PLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLP 416

Query: 685  GLPGADGPPGHP----GKEGQSGEKGALGPPGPQG---------PIGYPGPRGVKGADGV 731
            GLPG  G PG P    GK G+ G  G  G PG QG          +G PGP+G+KG  G 
Sbjct: 417  GLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGP 476

Query: 732  RGLKGSKGEKGEDGF-------------PGFKGDMGLKGDRGEVGQIGPRGEDGP---EG 775
             G +G KGEKG +G              PG  G  G KGD G  G +G +G+ GP   EG
Sbjct: 477  PGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEG 536

Query: 776  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 835
            P G  G  G  GP G  G KG + V  + G+ G +GP G  GFPG PG++G  G  G  G
Sbjct: 537  PPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKG 596

Query: 836  KPGPRGQR-----------GPTGPRGSRGARGPTGK--PGPKGTSGGDGPPGPPGERGPQ 882
             PGP G             GP GP G  G  GP G   PGP G  G  G PG PG RGP 
Sbjct: 597  DPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPD 656

Query: 883  G--------------------------PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGET- 915
            G                          P GP GFPGP+G PG  G DG  G PG  G   
Sbjct: 657  GLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAE 716

Query: 916  -----GFQGKTGPPGPGGV-----VGPQGPTGETGPIGERGHPGPP-----GPPGEQGLP 960
                 GF+G  G PG GG      VGP GP G  G  G++G PG P     GPPG++GL 
Sbjct: 717  IPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLS 776

Query: 961  GAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPP 1014
            G  G +G +GDPG     G +GPAG+ GF G +G  G +G  G  G  GP      +G P
Sbjct: 777  GVPGIKGPRGDPG---CPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAP 833

Query: 1015 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG---EKGPQGPAGRDGVQGPV 1071
            G  G PG  G  G+ G  G  G+PG  GPPGPAG KG PG     G  GP G  G+ GP 
Sbjct: 834  GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893

Query: 1072 G------LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1125
            G       PGP GP G PG  G  GE G+PG +G  G KGE G  G  GL G  G  G  
Sbjct: 894  GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAK 953

Query: 1126 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG-- 1183
            G  G PG  G+  +  QKG  G  G PG  G  G +G  G PG +G  G+ G  GPPG  
Sbjct: 954  GAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFH 1013

Query: 1184 --PPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
               PG +G  GP G  GP G  G  G +G  G  G+ GE G+PGPPG +G+ G +G +G 
Sbjct: 1014 RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGN 1073

Query: 1242 KGEA----GPPGAAGPPGAKGPPGDDGPKGNPG------PVGFPGDPGPPGEPGPAG--- 1288
            KG+     GPPG  G PG+ G PG  G  G  G      P G PG PGPPG  GP G   
Sbjct: 1074 KGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPG 1133

Query: 1289 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1348
              G+ G +G+ G+ G PGP G  G+ G PGPPG +GP G+ G  G  G KG KG  GA G
Sbjct: 1134 DHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASG 1193

Query: 1349 -----PPGKTG-----------------PVGPQGPAGKPGPEGLRGIPGPVGEQGL---- 1382
                 PPG  G                 P GP+G  G PGP G  G PGP G  G     
Sbjct: 1194 LHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKD 1253

Query: 1383 ---PGAAGQDGPPGPMGPPGLPGLKGDPGS----KGEKGHPGLIGLIGPPGEQGEKGDRG 1435
               PG  G  GPPGP GP G PG  G PGS    +GE G  GL G  GPPG  G  G +G
Sbjct: 1254 IPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313

Query: 1436 LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG 1495
             PG  G  G KG  G PGP GP G PGPPG          KG  GP G+KG +GLPGP G
Sbjct: 1314 FPGCDGKDGQKGPVGFPGPQGPHGFPGPPG---------EKGLPGPPGRKGPTGLPGPRG 1364

Query: 1496 SPGPPGEV 1503
             PGPP +V
Sbjct: 1365 EPGPPADV 1372



 Score =  722 bits (1864), Expect = 0.0
 Identities = 456/1126 (40%), Positives = 526/1126 (46%), Gaps = 194/1126 (17%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGH-------GAYGEKGQKGEPA----VVEPGMLVE 402
            P   P     PG P         + G        G YGE G  G P     +  PG    
Sbjct: 342  PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401

Query: 403  GPPGPAGPAGIMGPPGLQGPTGPPGDP----GDRGPPGRPGLPGADGLPGPPGTMLM--- 455
            G  GP GP G  G PGL G  G PG P    G  G PG PGLPGA GL G PG+ ++   
Sbjct: 402  GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCS 461

Query: 456  --------LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 507
                    +  + G  G +GP    +  +    L        GPPGP GL GR G  G  
Sbjct: 462  VGNPGPQGIKGKVGPPGGRGP----KGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL 517

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG------MPGEPGAKGDR 561
            G  G  G  GDPGP G    +GPPG  GK G  G PG  G +G      + G  G +G  
Sbjct: 518  GLPGWLGTKGDPGPPG---AEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPD 574

Query: 562  GFDGLPGLPGDKGHRGERGPQGPPGPPGDD-----GMRGEDGEIGPRGLPGEAGPRGL-- 614
            G  G PG PG  G  G  G +G PGPPGD      G +G  G +GP G  G  GP GL  
Sbjct: 575  GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634

Query: 615  ---LGPRGTPGAPGQPGMAG--------------------------VDGPPGPKGNMGPQ 645
                G RG PG PG PG+ G                           DGPPGPKG  GPQ
Sbjct: 635  PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 646  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD--GPPGHPGKEGQSG 703
            G PG  G  G+ G  G PG     GPPG +G  G PG  G  G+   GPPG PG  G +G
Sbjct: 695  GAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754

Query: 704  EKGA--------LGPPG------------PQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
            +KG         LGPPG            P+G  G PG  G  G  G  GLKG KG +G 
Sbjct: 755  QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814

Query: 744  DGFPG------------------------FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779
             GFPG                        + G  G  G +G+ G +GP G  G +G  G 
Sbjct: 815  AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874

Query: 780  AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG---VAGK 836
             G  G  GP G  G  G  G  GLPG PG +GP+G  GFPGFPG  G+ GA G     G+
Sbjct: 875  PGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGE 934

Query: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGT------SGGDGPPGPPGERGPQGPQGPVGF 890
            PG +G  G  G RG RGA+G  G PG +G        G  G PGPPG+ G  G +G  G 
Sbjct: 935  PGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGT 994

Query: 891  PGPKGPPGPPGKDGLPG-HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 949
            PG +G  G PG+ G PG H G+ GE G  G  GPPGP G  G +G  G  G  G++G PG
Sbjct: 995  PGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPG 1054

Query: 950  PPGPPGEQGLPGAAGKEGAKGDP-------GPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002
             PGPPG  G+ GA G +G KGDP       GP+G  G  G  G  G  GE+GLPG QG  
Sbjct: 1055 SPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPR 1114

Query: 1003 GLKGGEGPQGPPGPVGSPGERG---------SAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053
            G  G  GP G  GP G PG+ G           G  GP GL G PG  GPPG  G  G+P
Sbjct: 1115 GSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSP 1174

Query: 1054 GEKGPQGPAGRDGVQGPVGLP--GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1111
            G  G  G  G+ G +G  GL   GP GP G PG  G++G+ G PG     G +G+ GPPG
Sbjct: 1175 GLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS-PPGPRGKKGPPG 1233

Query: 1112 PPGLQGPVGA-------------PGIAGGDGEPGPRGQQG-------------MFGQKGD 1145
            PPG  GP G              PG  G  G PGP G +G             + G+ GD
Sbjct: 1234 PPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1293

Query: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205
             G  G PGPPGP G  G  G PG  G++G  GP+G PGP GP G  GP G  G  GPPG 
Sbjct: 1294 CGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR 1353

Query: 1206 VGSVGGVGEKGEPGEAGN-------PGPPGEAGVGGPKGERGEKGEAGP--PGAAGPPGA 1256
             G  G  G +GEPG   +       PG PG  G+ GP+G  G  G  GP  PG  G PG 
Sbjct: 1354 KGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGL 1413

Query: 1257 KGPPGDDGPKGNPGPVG---------FPGDPGPPGEPGPAGQDGVG 1293
             G  G DG  G+PGP G         +PG PGPPG  G  G  G G
Sbjct: 1414 DGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFG 1459



 Score =  681 bits (1756), Expect = 0.0
 Identities = 419/959 (43%), Positives = 493/959 (51%), Gaps = 141/959 (14%)

Query: 653  QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG 712
            ++G+ GP G PGPQGPIGP G  GP G  G  G+ G  GPP            GA G  G
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPP------------GAAGDKG 107

Query: 713  PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 772
             +GP G PG  G+ G  G  G  G +G+ G  G  G +GD G  G RG +G  GP G  G
Sbjct: 108  DKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPG 167

Query: 773  PEGPKGRA----GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA---N 825
             +G KG +    G        G  G++G  G+PGLPG  G  GP G TG+PG PG     
Sbjct: 168  EKGEKGNSVFILGAV-----KGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPP 222

Query: 826  GEKGARGVAGKPGP--RGQRGPTGPRGSRGARGPT------------GKPGPKGTSGGDG 871
            G+ G  G+ G PG   +GQ G  G  G +G+ GPT            G+ G KG  G  G
Sbjct: 223  GQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVG 282

Query: 872  PPGPPGERGPQG--PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
             PGPPG +G  G   +G  G PG  GP G PG  G PG PG +GE G     G PG  G+
Sbjct: 283  LPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGL---VGDPGLFGL 339

Query: 930  VGPQGPTGETGPIGERGHPGPPG-----------PPGEQGLPGAAGKEGAKGDPGPQGIS 978
            +GP+G  G       RGHPGPPG           PPG+ G PG  G+ G  G PGP G+ 
Sbjct: 340  IGPKGDPGN------RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLL 393

Query: 979  GKDGPA--GLRGFPGERGLPGAQGAPGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLP 1035
            G+ G A  G+ G PG +G PG  G PG  G  G P   PG  G PG  G  G  G  GLP
Sbjct: 394  GRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLP 453

Query: 1036 GRP------GPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLPGPAGPAGSPGE 1085
            G        G  GP G  G+ G PG +GP+G  G +G+     GP+G   P GP G PG 
Sbjct: 454  GSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMG---PPGPPGLPGR 510

Query: 1086 DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG---MFGQ 1142
             G KG++G PG  G+KGD      PGPPG +GP G PG  G  G PG +G +G   +   
Sbjct: 511  QGSKGDLGLPGWLGTKGD------PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRV 564

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD--GPQ 1200
            KG +G RG  GPPG       PG PG  G +G  G  G PGPPG      P G    GP 
Sbjct: 565  KGHKGERGPDGPPG------FPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618

Query: 1201 GPPGSVGSVG--GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA-----------GP 1247
            GPPG  G VG  G+G  G PGE G+PG PG  GV GP G +G+KG+            GP
Sbjct: 619  GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678

Query: 1248 PGAAGPPGAKGPPG---------DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1298
            PG  GPPG KG PG          DG KG PG  G    PGPPG  G  G  G GG+KG 
Sbjct: 679  PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS 738

Query: 1299 D--GDPGQPGPPGPSGEAGPPGPP--GKRGPPGAAGAEGRQGEKGAKGEAG---AEGPPG 1351
               G PG PG PG +G+ G PG P  G  GPPG  G  G  G KG +G+ G   AEGP G
Sbjct: 739  SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAG 798

Query: 1352 KTGPVGPQGPAGKPGPEGLRGIPGPVG---EQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1408
              G +G +GP G+ G  G  G+PGP G   E+G PG  GQ G PG  G PG PG KG PG
Sbjct: 799  IPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPG 858

Query: 1409 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1468
              G  G  G+ GL G PG  G  G  GLPG    PG  GD G+PGP GP GP G PG PG
Sbjct: 859  DVGPPGPAGMKGLPGLPGRPGAHGPPGLPGI---PGPFGDDGLPGPPGPKGPRGLPGFPG 915

Query: 1469 PQGPKGNKGSTGPAGQKGD------SGLP------GPPGSPGPPGEVIQPLPILSSKKT 1515
              G +G  G+ G  G KG+      SGLP      G  G+ GPPG+  + + I+S K T
Sbjct: 916  FPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE-MAIISQKGT 973



 Score =  637 bits (1642), Expect = 0.0
 Identities = 413/1006 (41%), Positives = 477/1006 (47%), Gaps = 204/1006 (20%)

Query: 351  EDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 410
            E  P  PP     PG+P      + S    G  G  G KG+P    PG   EGPPG  G 
Sbjct: 495  EPGPMGPPGP---PGLPGR----QGSKGDLGLPGWLGTKGDPG--PPG--AEGPPGLPGK 543

Query: 411  AGIMGPPGLQG------------------PTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 452
             G  GPPG +G                  P GPPG PG  G  GR G  G  G PGPPG 
Sbjct: 544  HGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGD 603

Query: 453  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGA 512
                    GG G  GP     +A     +    +   GPPG  G  G PG  G  G  G 
Sbjct: 604  HE--DATPGGKGFPGPLGPPGKAGP---VGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658

Query: 513  KGESGD--------PGPQGPRGVQGPPGPTGKPGKRGRPG---ADGGRGMPGEPGAKGDR 561
            KG+ GD        PG  GP G  GPPGP G PG +G PG   +DG +G PG PG     
Sbjct: 659  KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIP 718

Query: 562  GFDGLPGLPGDKGHRGERG--PQGPPGPPGDDGMRGEDG--------EIGPRGLPGEAGP 611
            G  G  G  GD G  GE+G  P GPPGPPG  G+ G+ G         +GP G  G +G 
Sbjct: 719  GPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGV 778

Query: 612  RGLLGPRGTPGAPGQ------PGMAGVDGPPGPKGNMGPQGEPGPPGQQ------GNPGP 659
             G+ GPRG PG PG       PG  G+ GP G +G+ G  G PGPPG        G PG 
Sbjct: 779  PGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQ 838

Query: 660  QGLPG------------PQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 707
             GLPG              G +GPPG  G +G PGL G PGA GPPG PG  G  G+ G 
Sbjct: 839  PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGL 898

Query: 708  LGPPGPQGP------IGYPGPRGVKGADGVRGLKGSKGEK-------------------- 741
             GPPGP+GP       G+PG RG  GA+G  G KG  GEK                    
Sbjct: 899  PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958

Query: 742  ----------------------GEDGFPGFKGDM---GLKGDRGEVGQIGPRG-EDGPEG 775
                                  G+DGFPG +GD    G++G RGE G+ GP G   G  G
Sbjct: 959  PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG 1018

Query: 776  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA- 834
             KG+ GP G PGP G  G +G +G PGLPG  G  G  G  GF G  GA G KG +G   
Sbjct: 1019 EKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 1078

Query: 835  ---GKPGPRGQR---------GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER--- 879
               G PGP+G+          G +G +G  G +GP G PG  G  G  GPPG PG+    
Sbjct: 1079 SHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMP 1138

Query: 880  ------------GPQGPQGPVGFPGP---KGPPGPPGKDGLPGHPGQRGETGFQG--KTG 922
                        GP+G QG  G PGP   KGP G PG +GL G  GQ+G  G  G    G
Sbjct: 1139 GLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198

Query: 923  PPGPGGVVGPQGPTGETG-----PIGERGHPGPPGPPGEQGLPGAAGKEGAK----GDPG 973
            PPGP G+ G +G  G+ G     P G RG  GPPGPPG  G PG AG  G       DPG
Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258

Query: 974  PQGISGKDGPAGLRGFPGERGLPGA----QGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1029
            P G  G  GP G RG PG  GLPG+    +G PG  G  GP GPPGP G PG +G  G  
Sbjct: 1259 PPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCD 1318

Query: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089
            G  G  G  G  GP GP G  G PGEKG  GP GR   +GP GLPGP G  G P +  D 
Sbjct: 1319 GKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR---KGPTGLPGPRGEPGPPADVDDC 1375

Query: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149
              I  PG  G+ G +G  G  G PG++GP G          PG +G+ G+ G++G +G  
Sbjct: 1376 PRI--PGLPGAPGMRGPEGAMGLPGMRGPSG----------PGCKGEPGLDGRRGVDGVP 1423

Query: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1195
            G PGPPG             KG+ G+ G  G PGPPGP G  GP G
Sbjct: 1424 GSPGPPG------------RKGDTGEDGYPGGPGPPGPIGDPGPKG 1457



 Score =  515 bits (1326), Expect = e-145
 Identities = 333/782 (42%), Positives = 371/782 (47%), Gaps = 143/782 (18%)

Query: 337  GDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAVV 395
            GD+G+  F   K     P  PP     PGV  +  I      GH G  G++G  G P + 
Sbjct: 725  GDMGDPGFGGEKG--SSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782

Query: 396  EPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD---PGDRGPPGR------PGLPGADGL 446
             P     G PG  GPAGI G  GL+GP G  G    PG  GPPG       PG+PG  GL
Sbjct: 783  GPRG-DPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841

Query: 447  PGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG 506
            PG PG+    P   GG G  G                      GPPGP G+ G PG  G 
Sbjct: 842  PGYPGS----PGAPGGKGQPGDV--------------------GPPGPAGMKGLPGLPGR 877

Query: 507  PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---PGAKGDRGF 563
            PG+ G  G  G PGP G  G+ GPPGP G  G  G PG  G RG PG    PGAKG+ G 
Sbjct: 878  PGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE 937

Query: 564  DGLPGLPGDKGHRGERGPQGPPG------------------PPGDDGMRGEDGEIGPRGL 605
             G+ GLPGD+G RG +G  GPPG                  PPGDDG  GE G+ G  G+
Sbjct: 938  KGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGM 997

Query: 606  PGEAGPRGLLGP----RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 661
             G  G  G  GP    RG PG  GQPG  G  GPPG  G  G  G PG PG QG PG  G
Sbjct: 998  QGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG 1057

Query: 662  LPG----------------PQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
             PG                P    GPPG KG  G PG  G  GA G  G PG +G  G  
Sbjct: 1058 PPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSP 1117

Query: 706  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765
            G  GPPG  GP G PG  G+ G  G  G  G  G +G  G PG  G  G+KG  G  G  
Sbjct: 1118 GRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN 1177

Query: 766  GPRGEDGPEGPKGRAG--PTGDPGPSGQAGEKGKLGVPGLPGY--PGRQGPKGSTGFPGF 821
            G  G  G +G KG +G    G PGP G  G KG+ G PG PG   PG +G KG  G PG 
Sbjct: 1178 GLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGS 1237

Query: 822  PGANGEKGARGVAGK----PGPRGQRGPTGPRGSRGARGPTGKPGP----KGTSGGDGPP 873
             G  G  GA G A K    PGP G +GP GP G RGA GP G PG     +G  G  G P
Sbjct: 1238 SGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP 1297

Query: 874  GPPGERGPQGP---------------QGPVGFPGPKGP---PGPPGKDGLPGHPGQRGET 915
            GPPG  GP GP               +GPVGFPGP+GP   PGPPG+ GLPG PG++G T
Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPT 1357

Query: 916  GFQGKTGPPGPG-------------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962
            G  G  G PGP              G  G +GP G  G  G RG P  PG  GE GL G 
Sbjct: 1358 GLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRG-PSGPGCKGEPGLDGR 1416

Query: 963  AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1022
             G +G  G PGP               PG +G  G  G PG     GP GPPGP+G PG 
Sbjct: 1417 RGVDGVPGSPGP---------------PGRKGDTGEDGYPG-----GP-GPPGPIGDPGP 1455

Query: 1023 RG 1024
            +G
Sbjct: 1456 KG 1457



 Score =  244 bits (624), Expect = 4e-64
 Identities = 148/322 (45%), Positives = 165/322 (51%), Gaps = 35/322 (10%)

Query: 1212 VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1271
            V EKG  G  G PGP G  G  G  G  G  GE G  G  GPPGA G  GD GP G PG 
Sbjct: 58   VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF 117

Query: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA-- 1329
             G  G PG PG PGP G+ G+ G  G  GDPG PG  G  G  GP G PG++G  G +  
Sbjct: 118  PGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVF 177

Query: 1330 --GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1387
              GA   +G +G +G+ G  G PG  G  GP GP G PG  GL G PG  G  GL G  G
Sbjct: 178  ILGAV--KGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG 235

Query: 1388 QDGPPGPMGPPGLPGLKGDP---------------GSKGEKGHPGLIGLIGPPGE----- 1427
              G  G MG PG  G +G P               G KG KG PG++GL GPPG      
Sbjct: 236  V-GVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294

Query: 1428 ---QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGPKGNKGSTGP 1481
               +GEKG  G PG +G PG+ G  G PG  G LG  G P   GL GP+G  GN+G  GP
Sbjct: 295  IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354

Query: 1482 AGQKGDSGLP--GPPGSPGPPG 1501
             G      LP  GPPG PG PG
Sbjct: 355  PGVLVTPPLPLKGPPGDPGFPG 376



 Score =  128 bits (321), Expect = 6e-29
 Identities = 89/220 (40%), Positives = 97/220 (44%), Gaps = 25/220 (11%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413
            P  P      PG+P   D+           GE G  G P    P     GPPGP G  G 
Sbjct: 1268 PDGPRGAPGPPGLPGSVDLLR---------GEPGDCGLPGPPGP----PGPPGPPGYKGF 1314

Query: 414  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LMLPFRYGGDGSKGPTIS 471
             G  G  G  GP G PG +GP G PG PG  GLPGPPG      LP   G  G  GP   
Sbjct: 1315 PGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLP---GPRGEPGPPAD 1371

Query: 472  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531
              +      L  A   +RGP G MGL G  GP G     G KGE G  G +G  GV G P
Sbjct: 1372 VDDCPRIPGLPGAP-GMRGPEGAMGLPGMRGPSG----PGCKGEPGLDGRRGVDGVPGSP 1426

Query: 532  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 571
            GP G+ G  G  G  GG G PG  G  G +GF   PG  G
Sbjct: 1427 GPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFG--PGYLG 1464



 Score =  104 bits (260), Expect = 7e-22
 Identities = 63/151 (41%), Positives = 77/151 (50%), Gaps = 21/151 (13%)

Query: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1437
            G +G PG  G  GP GP+G PG  GL G+ G +G++G         PPG  G+KGD+G  
Sbjct: 62   GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG---------PPGAAGDKGDKGPT 112

Query: 1438 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497
            G  G PG  G   IPG     GPPGP G PG  G  G++G  G  G +G  G  GP G P
Sbjct: 113  GVPGFPGLDG---IPGHP---GPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHP 166

Query: 1498 GPPGEVIQPLPILSSKKTRRHTEGMQADADD 1528
            G  GE    + IL + K      G+Q D  D
Sbjct: 167  GEKGEKGNSVFILGAVK------GIQGDRGD 191



 Score = 36.2 bits (82), Expect = 0.29
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 1484 QKGDSGLPGPPGSPGPPGEVIQPLPI-LSSKKTRRHTEGMQADADD 1528
            +KG  G PGPPG  GP G +  P PI LS +K  R   G    A D
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGD 105


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 437  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 495
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 496  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 545
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 546  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 602
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 603  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 655
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 656  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 708
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 709  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 757
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 758  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 801
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 802  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 844
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 845  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 895
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 955
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 956  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1015
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1016 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1074 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1121
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1178
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1236
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1290
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1291 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1334
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1392
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1393 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1441
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1492
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1493 PPGSPGPPGEV 1503
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  833 bits (2153), Expect = 0.0
 Identities = 510/1180 (43%), Positives = 594/1180 (50%), Gaps = 120/1180 (10%)

Query: 358  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 404
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 405  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 458
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 459  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 517
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 518  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 574  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 630  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 684
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 685  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 798
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 856
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 857  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 975  QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1087
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1088 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1144 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
             LPG+      PGP G PG PG++G+PG              GPPG  G  G RG PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPP------------GPPGNLGPCGPRGKPGKD 1396

Query: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG 1480
            G PG                      PGP G KGNKGS G
Sbjct: 1397 GKPGT---------------------PGPAGEKGNKGSKG 1415



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 561
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 562  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 618
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 619  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 668  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 717
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 718  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 764  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 806
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 807  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 857
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 858  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 879
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 880  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 984
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 985  GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1038 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1081
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1082 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1127
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1182
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1239
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1240 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1294 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1323
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1324 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1376 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1424
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1425 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1473
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPG 1498
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  780 bits (2015), Expect = 0.0
 Identities = 479/1110 (43%), Positives = 559/1110 (50%), Gaps = 113/1110 (10%)

Query: 326  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 374
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 375  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 428
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 429  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 482
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 483  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 538
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 539  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 590
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 591  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 646
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 647  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 707  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 765  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 817
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 818  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 872  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 922
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 923  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 983  PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1039
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1040 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1090
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1091 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1147 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1196
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1197 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1256
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1257 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
             GP G PGK G PG  G  G +G KG+KGE
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 673
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 674  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 727
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 728  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 774
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 775  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 887
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 888  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 938
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 939  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 981
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1092
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1093 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1203 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1252
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1253 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1295
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1404
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1405 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1448
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1449 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1504 IQPLP 1508
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 785  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 832
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 868
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 869  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 906
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 907  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 955
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 956  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1014 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1053
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1054 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1092
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1093 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1200
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1201 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1252 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1305 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1357
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1358 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1407
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1408 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1455
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1515
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1516 RRHTEGMQADADD 1528
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  494 bits (1272), Expect = e-139
 Identities = 309/729 (42%), Positives = 368/729 (50%), Gaps = 86/729 (11%)

Query: 357  PPNEEFGPGVPAETDITETSINGHGAYGEKG---------QKGEPAVVEPGML----VEG 403
            PP  +   G P     T+ S+   G  GE G          KGEPAV  PG        G
Sbjct: 704  PPGPKGDQGFPG----TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 404  PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 463
              G +G  G +G PGL G  G PG+ G  GP G PG PG  G  GPPG  +      G  
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIE-----GPR 814

Query: 464  GSKG-PTISAQEAQAQAILQQARIALRGPPGPMGL--TGRPGPVGGPGSSGAKGESGDPG 520
            G++G P ++  + Q     ++ +   +G PG  GL  +G PG  G PG  G +GE G  G
Sbjct: 815  GAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 521  PQG---PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 577
             +G     G+ GPPG  G  G  G PGA G  G PG PG  G RG    PG+PG KG RG
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS---PGIPGVKGQRG 928

Query: 578  ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637
              G +G  G  G+ G       IG +G PG  G  G  G +G  G PG PG+ G+ G PG
Sbjct: 929  TPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG 988

Query: 638  PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ---------GKPGLAGL-- 686
            P G  GP+G+ G  G  G PG +G+PG  G +G PG KG +         G+PGL G+  
Sbjct: 989  PAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048

Query: 687  ---------------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV 731
                           PG  GP G PG  G  G+KG +G PGP G +G  GP G  G+ G 
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108

Query: 732  RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 791
             GL G  G  G+ GF G KG +G  G RG  G  G  G  GP G +G  G  G PGP+G+
Sbjct: 1109 PGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 792  AGEKGKL-GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 850
             GE G L   PG  G PG QG KG  G PGFPG  G KGA G AG  GP G  G  GP G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 851  SRGA-----RGPTGKPGPKGTSGGDGPPGPPGER--GPQGPQGPVGFPGPKGPP------ 897
              GA      G  G PG +G+ G  GPPGPPG    G +G +G +G PGPKGPP      
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 898  GPPGK---DGLPGHPGQRGETGFQ------GKTGPPGPGGVVGPQGPTGETGPIGERGHP 948
            GPPG+    G PG PG RG+ GFQ      G+ G PG  G +GP GP G  GP G RG P
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 949  GP---PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLK 1005
            G       PG  G PG  G+ G +G+PGP G  G  GP G RG PG+ G PG  G  G K
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK 1408

Query: 1006 GGEGPQGPP 1014
            G +G +G P
Sbjct: 1409 GNKGSKGEP 1417



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1022 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1073 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1128 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1177
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1178 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1230 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1269
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1270 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1314
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1315 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1354
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1410
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1468
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1469 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1501
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  261 bits (668), Expect = 3e-69
 Identities = 168/400 (42%), Positives = 188/400 (47%), Gaps = 54/400 (13%)

Query: 335  VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 394
            + GD GE  + E          PP     PG+P             G  G+KG+ G+P  
Sbjct: 1049 LQGDKGEPGYSEGTR-----PGPPGPTGDPGLP-------------GDMGKKGEMGQPG- 1089

Query: 395  VEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRG------PPGRPGLPGADGLPG 448
              PG L  GP GP G  G  G PGL G  GP GD G +G      PPG  G PG  G PG
Sbjct: 1090 -PPGHL--GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146

Query: 449  PPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPG 508
             PG M +   + G DG  GP     E      L +A    RG PG  G  G  G  G PG
Sbjct: 1147 SPGPMGIRGDQ-GRDGIPGPAGEKGETG----LLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 509  SSGAKGESGDPGPQGPRGVQGPPGPTGKPG-----KRGRPGADGGRGMPGEPGAKGDRGF 563
              G KG  GD GP+GP G++G PGP G PG     + G  G  G RG PG PG  G  G 
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 564  DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 623
              + G+ GDKG  G  GP+GPPG  GD G  G  G  G  GLPG  G  G  G  G  G 
Sbjct: 1262 HVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE 1320

Query: 624  PGQPGMAGVDGPPGPKGNMGPQG---------------EPGPPGQQGNPGPQGLPGPQGP 668
             G PG  G  GPPGP G  GP G                PGPPG  G PG QG PGP GP
Sbjct: 1321 KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP 1380

Query: 669  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708
             G  G  GP+GKPG  G PG  GP G  G +G  GE  +L
Sbjct: 1381 PGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESL 1420



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1387 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1430
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1431 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1482
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1483 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1509
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1510 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1543
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 437  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 495
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 496  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 545
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 546  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 602
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 603  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 655
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 656  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 708
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 709  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 757
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 758  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 801
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 802  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 844
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 845  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 895
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 955
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 956  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1015
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1016 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1074 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1121
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1178
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1236
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1290
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1291 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1334
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1392
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1393 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1441
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1492
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1493 PPGSPGPPGEV 1503
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 358  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 404
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 405  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 458
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 459  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 517
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 518  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 574  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 630  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 684
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 685  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 798
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 856
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 857  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 975  QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1087
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1088 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1144 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1478
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 610  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 669
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 670  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 719
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 720  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 763
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 764  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 808
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 809  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 869  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 924  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 974  PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1031
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1032 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1084
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1085 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1131
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1189
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1190 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1242 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1298
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1299 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1391
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1392 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1444 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1490
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1491 ---PGPPGSPGPPG 1501
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 561
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 562  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 618
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 619  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 668  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 717
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 718  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 764  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 806
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 807  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 857
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 858  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 879
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 880  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 984
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 985  GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1038 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1081
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1082 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1127
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1182
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1239
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1240 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1294 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1323
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1324 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1376 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1424
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1425 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1473
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPG 1498
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 326  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 374
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 375  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 428
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 429  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 482
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 483  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 538
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 539  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 590
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 591  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 646
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 647  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 707  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 765  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 817
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 818  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 872  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 922
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 923  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 983  PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1039
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1040 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1090
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1091 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1147 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1196
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1197 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1256
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1257 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1372
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 673
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 674  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 727
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 728  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 774
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 775  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 887
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 888  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 938
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 939  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 981
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1092
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1093 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1203 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1252
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1253 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1295
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1404
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1405 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1448
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1449 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1504 IQPLP 1508
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 785  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 832
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 868
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 869  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 906
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 907  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 955
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 956  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1014 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1053
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1054 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1092
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1093 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1200
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1201 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1252 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1305 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1357
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1358 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1407
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1408 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1455
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1515
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1516 RRHTEGMQADADD 1528
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1022 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1073 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1128 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1177
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1178 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1230 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1269
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1270 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1314
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1315 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1354
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1410
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1468
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1469 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1501
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 381  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 436  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 490
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 491  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 532
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 533  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 593  MRGEDGEIGPRGLPGEAGPRGLLGPR 618
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1387 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1430
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1431 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1482
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1483 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1509
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1510 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1543
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 357  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 417  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 533
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 437  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 495
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 496  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 545
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 546  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 602
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 603  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 655
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 656  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 708
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 709  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 757
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 758  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 801
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 802  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 844
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 845  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 895
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 955
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 956  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1015
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1016 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1074 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1121
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1178
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1236
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1290
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1291 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1334
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1392
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1393 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1441
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1492
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1493 PPGSPGPPGEV 1503
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 358  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 404
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 405  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 458
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 459  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 517
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 518  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 574  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 630  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 684
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 685  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 798
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 856
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 857  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 975  QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1087
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1088 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1144 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1478
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 610  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 669
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 670  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 719
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 720  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 763
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 764  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 808
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 809  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 869  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 924  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 974  PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1031
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1032 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1084
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1085 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1131
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1189
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1190 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1242 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1298
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1299 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1391
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1392 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1444 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1490
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1491 ---PGPPGSPGPPG 1501
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 561
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 562  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 618
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 619  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 668  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 717
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 718  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 764  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 806
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 807  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 857
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 858  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 879
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 880  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 984
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 985  GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1038 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1081
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1082 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1127
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1182
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1239
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1240 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1294 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1323
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1324 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1376 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1424
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1425 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1473
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPG 1498
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 326  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 374
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 375  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 428
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 429  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 482
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 483  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 538
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 539  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 590
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 591  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 646
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 647  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 707  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 765  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 817
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 818  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 872  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 922
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 923  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 983  PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1039
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1040 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1090
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1091 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1147 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1196
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1197 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1256
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1257 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1372
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 673
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 674  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 727
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 728  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 774
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 775  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 887
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 888  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 938
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 939  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 981
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1092
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1093 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1203 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1252
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1253 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1295
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1404
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1405 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1448
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1449 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1504 IQPLP 1508
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 785  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 832
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 868
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 869  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 906
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 907  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 955
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 956  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1014 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1053
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1054 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1092
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1093 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1200
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1201 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1252 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1305 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1357
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1358 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1407
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1408 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1455
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1515
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1516 RRHTEGMQADADD 1528
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1022 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1073 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1128 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1177
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1178 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1230 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1269
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1270 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1314
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1315 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1354
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1410
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1468
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1469 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1501
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 381  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 436  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 490
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 491  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 532
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 533  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 593  MRGEDGEIGPRGLPGEAGPRGLLGPR 618
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1387 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1430
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1431 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1482
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1483 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1509
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1510 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1543
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 357  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 417  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 533
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 436
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 437  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 495
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 496  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 545
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 546  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 602
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 603  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 655
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 656  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 708
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 709  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 757
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 758  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 801
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 802  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 844
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 845  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 895
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 955
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 956  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1015
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1016 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1073
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1074 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1121
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1122 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1178
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1236
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1290
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1291 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1334
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1335 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1392
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1393 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1441
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1492
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1493 PPGSPGPPGEV 1503
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 358  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 404
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 405  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 458
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 459  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 517
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 518  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 574  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 630  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 684
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 685  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 743
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 798
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 856
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 857  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 915  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 974
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 975  QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1031
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1087
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1088 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1144 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1260
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1261 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1441 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1478
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 490  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 550  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 610  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 669
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 670  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 719
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 720  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 763
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 764  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 808
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 809  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 869  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 923
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 924  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 974  PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1031
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1032 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1084
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1085 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1131
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1132 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1189
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1190 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1242 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1298
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1299 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1391
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1392 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1444 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1490
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1491 ---PGPPGSPGPPG 1501
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 561
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 562  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 618
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 619  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 668  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 717
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 718  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 764  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 806
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 807  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 857
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 858  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 879
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 880  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 930  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 984
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 985  GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1038 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1081
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1082 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1127
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1128 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1182
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1239
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1240 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1293
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1294 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1323
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1324 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1375
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1376 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1424
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1425 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1473
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1474 GNKGSTGPAGQKGDSGLPGPPGSPG 1498
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 326  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 374
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 375  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 428
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 429  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 482
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 483  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 538
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 539  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 590
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 591  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 646
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 647  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 707  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 764
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 765  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 817
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 818  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 871
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 872  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 922
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 923  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 983  PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1039
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1040 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1090
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1091 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1146
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1147 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1196
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1197 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1256
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1257 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1372
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 616  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 673
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 674  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 727
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 728  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 774
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 775  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 832
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 887
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 888  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 938
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 939  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 981
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1037
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1092
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1093 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1203 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1252
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1253 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1295
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1404
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1405 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1448
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1449 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1504 IQPLP 1508
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 785  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 832
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 833  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 868
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 869  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 906
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 907  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 955
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 956  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1013
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1014 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1053
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1054 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1092
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1093 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1144
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1200
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1201 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1251
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1252 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1305 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1357
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1358 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1407
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1408 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1455
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1515
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1516 RRHTEGMQADADD 1528
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 962  AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1022 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1072
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1073 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1127
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1128 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1177
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1178 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1230 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1269
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1270 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1314
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1315 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1354
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1355 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1410
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1468
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1469 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1501
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 381  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 435
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 436  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 490
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 491  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 532
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 533  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 593  MRGEDGEIGPRGLPGEAGPRGLLGPR 618
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1386
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1387 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1430
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1431 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1482
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1483 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1509
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1510 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1543
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 357  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 417  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 533
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  871 bits (2250), Expect = 0.0
 Identities = 533/1213 (43%), Positives = 606/1213 (49%), Gaps = 174/1213 (14%)

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 473
            GP  +   T PP  P    PP RP  PG++ +          P    G+ G  GP     
Sbjct: 441  GPCQVTVVTEPPPPP----PPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM---- 492

Query: 474  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 533
                            G PGP G  G  GPVG PG  G KG+ G     GP G QG  G 
Sbjct: 493  ----------------GLPGPKGDIGAIGPVGAPGPKGEKGDVGI----GPFG-QGEKGE 531

Query: 534  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 593
             G  G  G PG DG +GM GEPG  G+      PGLPG+ G RG +GP G PGPPG  G 
Sbjct: 532  KGSLGLPGPPGRDGSKGMRGEPGELGE------PGLPGEVGMRGPQGPPGLPGPPGRVGA 585

Query: 594  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGP 650
             G  GE G +G  GE G RGL G  G PG  GQ   PG +GV GP G KG++GP G PG 
Sbjct: 586  PGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV 645

Query: 651  PG----------QQGNPGP---QGLPGP---QGPIGPPGEKGPQGKPGLAGLPGADGPPG 694
            PG          +QG PGP   QG PGP   +GPIGP G  GP G  GL G  G  GPPG
Sbjct: 646  PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705

Query: 695  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754
             PG  G  G      PPGP G  G PGP G  G  G  G  G  G  G  G PG  G  G
Sbjct: 706  IPGLLGLQG------PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNG 759

Query: 755  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 814
              G  G  G+ G RGEDG  G  G  G  G+ G +G+ GEKG+ G+PG PG+PG +G KG
Sbjct: 760  PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819

Query: 815  STGFPG---FPGANGEKGARGVAGKPGPRGQRGPTG-----PRGSRGARGPTGKPGPKGT 866
              G  G    PG  G++G +G AG  GP G  G T      PR   G +GP G+ G  G 
Sbjct: 820  DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR-MPGEQGPKGEKGDPGL 878

Query: 867  SGGDGPPGPPGERGPQGPQGPVGFPGPKGP---PGPPGKDGLPGHPGQRGETGFQGKTGP 923
             G  G  G PGE GPQGP GP G  G +G    PG  G  G PGH G  G +G  G  G 
Sbjct: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938

Query: 924  PGPGGVVGPQGPTGETGPIGERGHPGPPGP---PGEQGLPGAAGKEGAKGDPGPQGISGK 980
            PG  G  G  G  GE G  GE G PGP GP   PG  GLPG  GK G  G+PG +G  G 
Sbjct: 939  PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGL 997

Query: 981  DGPAGLRG-----------------FPGERGLPGAQGAPGLKG--GEGPQGPPGPVGSPG 1021
             GP G +                    G+RG PG  G+PG +G  G G  GPPGP G PG
Sbjct: 998  PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057

Query: 1022 ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL-------- 1073
            ++GS G+ G   LPG PGPQGP G  G  G PGE+GP G  G   +  P  +        
Sbjct: 1058 DKGSPGSRG---LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114

Query: 1074 ----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG---PPGLQGPVGAPGIAG 1126
                PGP G  G PG  GDKG  G+PG++G++G KGE GPPG   PPG+ GP G+ G  G
Sbjct: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174

Query: 1127 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186
             DGE G +G QG  G  G  G  G PGPPG  G+ G  GPPG +G  G  GP GP GP G
Sbjct: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234

Query: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG------EAGVGGPKGERG 1240
              G  G  G +G  G PG  G  G  GE G PG  G  GPPG      ++G  GP+GE G
Sbjct: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294

Query: 1241 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1300
              G  G  G  G  G  GP G  GP+G  GP G  G PG PGEPGP+G  G  G KGE+G
Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354

Query: 1301 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1360
             PG PG  GP G   PPG PG++G PG  G  G+ GE G KGE G  G  G  GP G +G
Sbjct: 1355 SPGLPGFLGPRG---PPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411

Query: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-------------- 1406
              G PG  G +G  G +G QGLPG  G  GPPGP G PG PGL+G+              
Sbjct: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471

Query: 1407 ---------------------------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
                                       PG  G  G  GL G  GP GE G  G  GL G 
Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 1531

Query: 1440 ------QGSPGAKGDGGIPGPA--GPLGPPGPPGLPGPQG--PKGNKGSTGPAGQKGDSG 1489
                  +G  GAKGD G PG    G +GPPG PG PG  G    G  G  GP G+ G +G
Sbjct: 1532 SGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1591

Query: 1490 LPGPPGSPGPPGE 1502
             PG PG PGPPG+
Sbjct: 1592 HPGLPGPPGPPGQ 1604



 Score =  854 bits (2206), Expect = 0.0
 Identities = 528/1205 (43%), Positives = 601/1205 (49%), Gaps = 164/1205 (13%)

Query: 353  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 412
            +P  PP  +  P   +E      +IN     GEKG+ G          V GP G  GP G
Sbjct: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMG----------VAGPMGLPGPKG 499

Query: 413  IMGPPGLQGPTGPPGDPGDRG----PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 468
             +G  G  G  GP G+ GD G      G  G  G+ GLPGPPG           DGSKG 
Sbjct: 500  DIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGR----------DGSKGM 549

Query: 469  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 528
                 E     +     + +RGP GP GL G PG VG PG  G +GE G  G +G RG+ 
Sbjct: 550  RGEPGELGEPGL--PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD 607

Query: 529  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP-------GLPGDKGHRGERGP 581
            G PG  G  G++GRPG  G  G  GE G  G  G  G+P       GL G++G  G RG 
Sbjct: 608  GFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGH 667

Query: 582  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP---GAPGQPGMAGVDGPPGP 638
            QG PGPPG  G  G +G  GP GL G  G +G +GP G P   G  G PG  GV GPPGP
Sbjct: 668  QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 639  KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGK 698
             G+ G  GE G PG+ G PGP G PG  GP GPPG  G +G+PG     G DG PG PG 
Sbjct: 728  GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER---GEDGLPGKPGL 784

Query: 699  EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 758
             G+ GE+G  G PG +G  G P   G  G  GVRG KG +GEKGE G P      GLKGD
Sbjct: 785  RGEIGEQGLAGRPGEKGEAGLP---GAPGFPGVRGEKGDQGEKGELGLP------GLKGD 835

Query: 759  RGEVGQIGPRGEDGPEGPKGRAGP----TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 814
            RGE G+ GP G  G  G      P     G+ GP G+ G+ G  G PGL G PG  GP+G
Sbjct: 836  RGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQG 895

Query: 815  STGFPGFPGANGEKGARGVAGKPGPRGQ---RGPTGPRGSRGA---RGPTGKPGPKGTSG 868
             TG PG  G  G  GA G AG PG  G     GP+GP GS GA   RG  GK G +G  G
Sbjct: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955

Query: 869  GDGPPGPPGERGPQGPQGPVGFPGP--KGPPGPPGKDGLPGHPGQRGETGFQGKT----- 921
              G  G PG  GP+G  G  G PGP  KG  G PG  G PG PG  G     GK      
Sbjct: 956  AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSEN 1015

Query: 922  ---------GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972
                     G  G  G+ G  G  G+ G IG  G PGP GPPG++G PG+ G  G  G  
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074

Query: 973  GPQGISGKDGPAGLRGFPGERGL---------------------PGAQGAPGLKGGEGPQ 1011
            GP G  G  G  G RG PG+ GL                     PG  G PGL G +G +
Sbjct: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071
            G PG  G  G  G  G AGP GLPG PG  GP G  GE+GA GE G +G  G  GV G +
Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194

Query: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL---------------Q 1116
            G PG  GP   PG DG  G  G PG +GS G +G  GP GP GL                
Sbjct: 1195 GPPGNPGP---PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251

Query: 1117 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV 1176
            GP G PG AG  G PGP G +G  G KG  G  G PGP G  G  GLPG  G  G++GD 
Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311

Query: 1177 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1236
            GP GP GP GPRGP G NG+ G  G PG  G+    G+KG  GE G+PG PG  G  GP 
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQKGSKGENGSPGLPGFLGPRGPP 1368

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1296
            GE GEK   G PG  G PG  G PG  G +G+P   G  GD GPPG  G  G  G+ G K
Sbjct: 1369 GEPGEK---GVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKGQPGDPGIPGHK 1422

Query: 1297 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--------------GRQGE----- 1337
            G  G  G  G PG +G  GPPGPPG+ G PG  G                G+Q E     
Sbjct: 1423 GHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAY 1482

Query: 1338 ----------KGAKGEAGAEGPPGK---TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1384
                      K ++G  G  GPPGK    G  GP G  G+PG  GL G  GP+G +G  G
Sbjct: 1483 LLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERG 1542

Query: 1385 AAGQDGPP-----GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
            A G  G P     G MGPPG+PG  G+PG   +    GL G+ GP GE G  G  GLPG 
Sbjct: 1543 AKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD----GLPGIPGPQGETGPAGHPGLPGP 1598

Query: 1440 QGSPG 1444
             G PG
Sbjct: 1599 PGPPG 1603



 Score =  684 bits (1766), Expect = 0.0
 Identities = 479/1364 (35%), Positives = 604/1364 (44%), Gaps = 249/1364 (18%)

Query: 65   KNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNE 121
            K   G+ ++Y       +   T+ +FP G  P++++ + T + +K  +    ++  + ++
Sbjct: 260  KRENGAQSSYVRMGSFPVVQSTEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQ 318

Query: 122  HGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR---TVNIADGKWHRVAISVEKKTVTM 178
            + I Q+ + +      +  +  G        +FR     ++ D  WH++A+S++ + V++
Sbjct: 319  YSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSL 378

Query: 179  IVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAY--DYC 236
             +DC    T P++  ER  +D  G TV G R+ D    + D+Q+ +I  D + A     C
Sbjct: 379  HIDCALVQTLPIE--ERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCC 436

Query: 237  EHYSPDCD----SSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTE----------A 282
            +  S  C     +  P     Q P    +  +   +  N       + E           
Sbjct: 437  DIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPG 496

Query: 283  PRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEY 342
            P+   G   P        E+   G     Q +  E          GRD    + G+ GE 
Sbjct: 497  PKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL 556

Query: 343  DF------YEYKEYEDKP--TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 394
                       +  +  P    PP     PG+  E     T     G  GE+G  G P  
Sbjct: 557  GEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT----RGEKGERGLDGFPG- 611

Query: 395  VEPGML-VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGD-------RGPPGRPGLPGADGL 446
             +PG    +G PGP+G AG  G  G  GP GPPG PG        +G  G PG  G  G 
Sbjct: 612  -KPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGA 670

Query: 447  PGPPGTMLMLPFRYGGDGSKGPT----ISAQEAQAQAILQQARIALRGPPGPMGLTGRPG 502
            PGPPG    +    G +G  GP     +  ++           + L+GPPGP G+ G PG
Sbjct: 671  PGPPGARGPI----GPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG 726

Query: 503  PVGGPGSSGA---KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 559
            P G PG  G     G+ G PGP GP G  GP GP G PG +G PG  G  G+PG+PG +G
Sbjct: 727  PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786

Query: 560  DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRG 619
            + G  GL G PG+KG  G  G  G PG  G+ G +GE GE+G  GL G+ G +G  GP G
Sbjct: 787  EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 846

Query: 620  TPGAPG-------QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP------Q 666
             PG PG        P M G  GP G KG+ G  GEPG  G+ G  GPQG  GP      +
Sbjct: 847  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906

Query: 667  GPIGPPGEKGPQGKPGLAGLPGADGPPGH---------PGKEGQSGEKGALGP---PGPQ 714
            G  G PG  G  G PG  G PG  GPPG          PGK+G+ GEKGA G    PGP 
Sbjct: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPV 966

Query: 715  GPIGYPGPRGV-----KGADGVRGLKGSKG--------------------------EKGE 743
            GP G PG  G+     KG DG  GL+GS G                           KG+
Sbjct: 967  GPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGD 1026

Query: 744  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGL 803
             G PG  G  G +GD G +G  GP G  GP G KG  G  G PG  G  G  G+ G PG 
Sbjct: 1027 RGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085

Query: 804  PGYPGRQGPKGST---------------------GFPGFPGANGEKGARGVAGKPGPRGQ 842
            PG  G  G  G +                     G PG PG  G KG +GV GKPG  G 
Sbjct: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT 1145

Query: 843  RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902
             G  G  G  G  GP G  GP+G+ G  G  G  G++G QG  G  GF GP G PGPPG 
Sbjct: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205

Query: 903  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962
            DG+ G  G  G  G  GK GPPGP G  G  G  GE G  G  G PGPPG PG+ G PG 
Sbjct: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265

Query: 963  AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP--------- 1013
             G EGA+G PG +G +G  G  G RG  G  GLPG +G PG  G  GP GP         
Sbjct: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325

Query: 1014 ------------PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE------ 1055
                        PGP G+PG++GS G  G  GLPG  GP+GPPG  GEKG PG+      
Sbjct: 1326 PGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK 1385

Query: 1056 ---------------KGPQGPAGRDGVQGPVGLPGPAG------PAGSPGEDGDKGEIGE 1094
                           KG +GP G  G  G  G+PG  G      P G PGE+G  G  G 
Sbjct: 1386 PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGP 1445

Query: 1095 PGQKGSKGDKGEN--------------------------------------GPPGPPGLQ 1116
            PGQ G  G +GE+                                      G PGPPG  
Sbjct: 1446 PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPP 1505

Query: 1117 GPVGAPGIAGGDGEPGPRGQQGM------FGQKGDEGARGFPGPPGPIGLQG-------- 1162
            G  G PG AG  GEPG  GQ G+       G KG+ GA+G PG PG +GL+G        
Sbjct: 1506 GKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIP 1564

Query: 1163 ------------LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1194
                        LPG PG +GE G  G  G PGPPGP G   P+
Sbjct: 1565 GQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608



 Score =  652 bits (1683), Expect = 0.0
 Identities = 385/876 (43%), Positives = 438/876 (50%), Gaps = 157/876 (17%)

Query: 776  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 835
            P G  G  G  GP G  G KG +G  G  G PG +G KG  G   F    GEKG +G  G
Sbjct: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPF--GQGEKGEKGSLG 536

Query: 836  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 895
             PGP G+ G  G RG  G  G  G PG  G  G  GPPG PG  G  G  G  G  G KG
Sbjct: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596

Query: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP----P 951
              G  G+ GL G PG+ G+TG QG+   PGP GV GPQG  G+ GP G  G PG      
Sbjct: 597  TRGEKGERGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQE 653

Query: 952  GPPGEQGLPGAAGKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008
            G  GEQG PG  G +GA G PG   P G  G+DGP GL+G  G++G  G  G PGL G +
Sbjct: 654  GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQ 713

Query: 1009 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP------------QGPPGPAGEKGAPGEK 1056
            GP GPPG  G PG  GS G  G IG PG+PGP             GPPGP G KG PGE+
Sbjct: 714  GPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773

Query: 1057 GP---------------QGPAGRDGVQGPVGLPGPAGPAGSPGEDGD---KGEIGEPGQK 1098
            G                QG AGR G +G  GLPG  G  G  GE GD   KGE+G PG K
Sbjct: 774  GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833

Query: 1099 GSKGDKGENGPPGPPGL----------------QGPVGA---------PGIAGGDGEPGP 1133
            G +G+KGE GP GPPGL                QGP G          PG+ G  GE GP
Sbjct: 834  GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893

Query: 1134 RGQQGMFGQKGDEGARGFPG------------------PPGPIGLQGLPGPPGEKGENGD 1175
            +G  G  G KG EGA G PG                  PPG +G  GL G PG+ GE G+
Sbjct: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953

Query: 1176 VGPMGPPGPPGPRGPQGPNGADGPQGPPG-----------------------SVGSVGGV 1212
             G  G  G PGP GP+G  GA G  GPPG                       + G V G 
Sbjct: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGS 1013

Query: 1213 -----------GEKGEPGEAGNPGPPGEAGVG-----GPKGERGEKGEAGPPGAAGPPGA 1256
                       G++G PG  G+PG  G+ G+G     GP G  G+KG  G  G  G PG 
Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073

Query: 1257 KGPPGDDGPKGNPGPVGFPGDPG---------------------PPGEPGPAGQDGVGGD 1295
            +GP G DG  GNPG  G PG PG                     PPG PG  G  G  GD
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133

Query: 1296 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1355
            KG  G PG+ G  G  GEAGPPG PG   PPG AG +G QGE+GA GE G +G  G  G 
Sbjct: 1134 KGVPGKPGREGTEGKKGEAGPPGLPG---PPGIAGPQGSQGERGADGEVGQKGDQGHPGV 1190

Query: 1356 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1415
             G  GP G PGP G  GI G  G  G+ G+ G++GPPGP GP GLPG+ G+ G +G  G 
Sbjct: 1191 PGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGK 1250

Query: 1416 PGLIGLIGPPGEQGEKGDRGLPGTQGS---PGAKGDGGIPGPAGPLGPPGPPGLPGPQGP 1472
            PG      PPGE G+ G+ GLPG +G+   PG KG  G  G  GP G  G  GLPG +G 
Sbjct: 1251 PG------PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 1304

Query: 1473 KGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508
             G  G TGP G +G  G  GPPG  G PG   +P P
Sbjct: 1305 PGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340



 Score =  229 bits (584), Expect = 2e-59
 Identities = 165/469 (35%), Positives = 194/469 (41%), Gaps = 143/469 (30%)

Query: 364  PGVPAETDIT--ETSINGHGAYGEKGQKGE---PAVVEPGMLVE----GPPGPAGPAGIM 414
            PG+P    I   + S    GA GE GQKG+   P V  PG +      GPPG  G AG  
Sbjct: 1155 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV--PGFMGPPGNPGPPGADGIAGAA 1212

Query: 415  GPPGLQGPTGPPGDPGDRGPPGRPGLPGA------DGLPGPPGTMLML--PFRYGGDGSK 466
            GPPG+QG  G  G PG +GP G PG+PG       DG PGPPG       P   G +G++
Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272

Query: 467  GPTI------------SAQEAQAQAILQQARIALR-------GPPGPMGLTGRPGPVGGP 507
            GP                 E+ A  +  Q  +  +       GP GP G  G PG  G P
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 508  GSSGAKGESGDPGPQGPRGVQGPPG---------PTGKPGKRGRPGADGGRGMPGEPGAK 558
            GS G  G SG PG +G +G  G PG         P G+PG++G PG +G  G PGEPG K
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392

Query: 559  GDRGFDGL---------------PGLPGDKGHRG---------ERGPQGPPGPPGDDG-- 592
            G+RG  G+               PG+PG KGH G         E GP GPPGPPG  G  
Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452

Query: 593  ---------------------------------------MRGEDGEIGPRGLPGEAGPRG 613
                                                   M+   G  GP G PG+ G  G
Sbjct: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512

Query: 614  LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPG--------------------- 652
              GP G PG PGQ G+ G  GP GPKG  G +G+PG PG                     
Sbjct: 1513 RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGY 1572

Query: 653  ----------QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 691
                       QG  GP G PG  GP GPPG+  P      A L    G
Sbjct: 1573 AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  830 bits (2145), Expect = 0.0
 Identities = 535/1293 (41%), Positives = 632/1293 (48%), Gaps = 175/1293 (13%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G  G+KG KG+P V+ PG       G  G  G+ G  G+ GP G PG PG  GP G PGL
Sbjct: 149  GLPGQKGSKGDP-VLAPGSF----KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGL 203

Query: 441  PGADGLPGPPGTMLMLPFRYGGD----------GSKGPTISAQEAQAQAILQQARIALRG 490
             G  G PGP G    +   + G+          G  GP  S  E +      + +   +G
Sbjct: 204  QGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKGSKG 262

Query: 491  PPGPMGLTGRPGPVGGPG--SSGAKGESGD------PGPQGP---RGVQGPPGPTGKPGK 539
             PGP G  G  GP G PG  ++G KGE G+      PGP+GP    GVQGPPG  GK G 
Sbjct: 263  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 322

Query: 540  RGRPGADGGRGMPGEPG-----------------AKGDRGFDGLPGLPGDKGHRGERGPQ 582
             G PG +G +G+ G+ G                   G+ G  G+PGLPG KG  G +G +
Sbjct: 323  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 382

Query: 583  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 642
            GP G PG   + G  G +GP+G PG  G +G  G R T GA G PG  G+ GPPGP G  
Sbjct: 383  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPP 441

Query: 643  GPQ-----------GEPGPPGQQGNPGPQGLPGPQGP------------IGPPGEKGPQG 679
             P+           G PG  G+QG  G  GL G +G              GPPGE GP G
Sbjct: 442  SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 501

Query: 680  KPGLAGLPGADGPPGHPGKEGQSGEKGA------LGPPGPQGPIGYP------GPRGVKG 727
              GL GLPG  G  G  G  G  G  GA      LGP GP+G  G P      G  G +G
Sbjct: 502  PWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRG 561

Query: 728  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787
              G +G +G  GE G+DG PG  G  GL GD G+ G  G +G  G  G KG  GP G PG
Sbjct: 562  DSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG 620

Query: 788  --------PSGQAGEKGKLGVPG---LPG---------YPGRQGPKGSTGFPGFPGANGE 827
                    P G  G+KGK G+PG   LPG          PG  GP G  G PGFPG  G 
Sbjct: 621  NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680

Query: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887
            +G  G  G+PG  G +G  G  G        G PGP+G  G  G PG PG+ G  G  G 
Sbjct: 681  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740

Query: 888  VGFPGPKGP-----------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 936
             G PG KG            PG  G  GL GH G  G++G  G  G  G  G++GP+G  
Sbjct: 741  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800

Query: 937  GETGPIGERGHPGPPGPPG------EQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---R 987
            G  G  G+ G PG PG  G      + GLPGA G  G  G PG +G  GK GP G    +
Sbjct: 801  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 860

Query: 988  GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1047
            G PG +GLPG  G  GLKG  G  G  G     G +G  G+ G +G PG PG  G PG  
Sbjct: 861  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 920

Query: 1048 GEKGAPGEKGPQGPAGRDGVQG---------PVGLPGPAGPAGS---PGEDGDKGEIGEP 1095
            G KG PG  G  GP+GR G  G         PVG+P P  P  +    G+ G +G  G  
Sbjct: 921  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 980

Query: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-DGEPGP---RGQQGMFGQKGDEGARGF 1151
            G  G +GDKGE G PGPPGL G  G PGI  G  G+PGP    G +G+ G KG  G  GF
Sbjct: 981  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040

Query: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPG 1204
            PG PG  G QG+ G PG  G +G  G  G         G PGP+G  G +G  G +G  G
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100

Query: 1205 SVGSVGGVGEKGEPG------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---PG 1255
             +G++G  G KGE G      + G PG PG  GV G +GE G  G +G  GA GP   PG
Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160

Query: 1256 AKGP------PGDDGPKGNPGPVGFPGDPGPP--GEPGPAGQDGVGGDKGEDG-DPGQPG 1306
              GP      PG  G  G PG  G  G PGP   G PGPAG  G  G+KG  G   G PG
Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1220

Query: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366
             PG  G+ G  G PG +GP G  GA G        G+ G  G PG  G  G  GPAG PG
Sbjct: 1221 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPG 1280

Query: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---IG 1423
            P G     G  G+ G PG  G  GP G  G PG  GL G+ G KG +G PG +G    +G
Sbjct: 1281 PPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1340

Query: 1424 PPGEQGEKGDRGLPGTQGSPGAKGDGG-------IPGPAGPLGPPGPPGLPGPQGPKGNK 1476
            PPG+ G  G +G  G +GS G +GD G       +  P GPLG PG  G+PG  G  G +
Sbjct: 1341 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ 1400

Query: 1477 GSTGPAGQKGDSGLPG---PPGSPGPPGEVIQP 1506
            G  G  G KG  G+PG   P G PGPPG +  P
Sbjct: 1401 GPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDP 1433



 Score =  819 bits (2116), Expect = 0.0
 Identities = 548/1326 (41%), Positives = 635/1326 (47%), Gaps = 209/1326 (15%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G+ G  G KGE     PG+L  GP GP G  G MG PG  G  G PG PG  GP G PGL
Sbjct: 68   GSTGLSGLKGERGF--PGLL--GPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGL 123

Query: 441  ------PGADGLPGPPG--TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 492
                   GA G PGP G   +L  P   G  GSKG  + A  +            ++G P
Sbjct: 124  DGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK---------GMKGDP 174

Query: 493  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK--RGRPGADGGRG 550
            G  GL G  GP G PG  GA G +G PG QGP G  GP GP G  G   +G  G  G  G
Sbjct: 175  GLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVG 234

Query: 551  MP---GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP---GPPGDDGM--RGEDGEIGP 602
            +P   G P + G+  F G P   G KG +GE GP+G P   GPPG  G+   GE GE G 
Sbjct: 235  LPGPAGPPPSTGELEFMGFP--KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGE 292

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE------PGP------ 650
            +G+PG  GPRG +G  G  G PGQ G  G  G PG  G  G +G+      PGP      
Sbjct: 293  KGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDI 352

Query: 651  -----PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG---LAGLPGADGPPGHPGKEGQS 702
                  G  G+PG  GLPG +G  G  G +GP G PG   L+G+PGA GP G PG +G  
Sbjct: 353  DGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQ 412

Query: 703  GEKGAL--------------GPPGPQGP--------------IGYPGPRGVKGADGVRGL 734
            G  G                GPPGP GP               G+PG RG +G  G  GL
Sbjct: 413  GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGL 472

Query: 735  KGSKGEK---------------GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779
            KG KG+                GE G PG  G +GL G +G  G  G  G  GP G  G 
Sbjct: 473  KGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL 532

Query: 780  AGPTGDPGPSGQAGE---------------KGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
             GP G  GP G+ GE                G  G  G+ G PG+ G  G  G PG PG 
Sbjct: 533  VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD 592

Query: 825  NGE--KGARGVAGKPGPRGQRGPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG 880
             G+   G +G+ G PG +G  GP G    G  G  GP G PG KG  G  G  G PG +G
Sbjct: 593  GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG 652

Query: 881  ------PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 934
                    G  GP GFPG  G PGP G  GLPG PGQ G +G +G+  P  PG V  P+ 
Sbjct: 653  ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE--PGSPGLVHLPEL 710

Query: 935  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----ISGKDGPAGLRGF 989
            P G  GP GE+G PG PG PG+ GLPG  G  G  G  G  G      +G  G  GL+G 
Sbjct: 711  P-GFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGL 769

Query: 990  PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
             G +G  G  G PGLK   G  G PG +G  GERGS GT G +G PG PG  GP G  G+
Sbjct: 770  TGHKGFLGDSGLPGLK---GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 826

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109
             G PG  G  G +G  G +G  G  GP G     G  G KG  G PG  G KG  G  G 
Sbjct: 827  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 886

Query: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169
             G P L GP G  G  G  G PG  G  G+    G  G +G PG  G +G  G  G PGE
Sbjct: 887  AGLPALSGPKGEKGSVGFVGFPGIPGLPGI---PGTRGLKGIPGSTGKMGPSGRAGTPGE 943

Query: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
            KG+ G+ GP+   G P PR P       G +G  GS GS G  G +G+ GEAG PGPPG 
Sbjct: 944  KGDRGNPGPV---GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGL 1000

Query: 1230 AGVGGPKG-ERGEKGEAGPP---GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285
             G  G  G  +G  G+ GPP   G  G PG KG  G  G  G PG  G  G  G PG PG
Sbjct: 1001 PGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1060

Query: 1286 PAGQDGVGGDKGE----DGDPGQPGPPGPSGEAGPPGP---------PGKRGPPGAAGAE 1332
             +G  G+ GD G+     G PG  G PG SG  G  G          PG +G  G  G  
Sbjct: 1061 ASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVS 1120

Query: 1333 GRQGEKGA---------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1383
            G  G  GA         +GE G  G  G  G +GP G  G  GP+G  G PG  G  GLP
Sbjct: 1121 GDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLP 1180

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL-IGLIGPPGEQGEKGDRGLPGTQ-- 1440
            G  G  G PGP    G+PG  G PG KGEKG+PG+ IG  G PG +G+KGDRG PG Q  
Sbjct: 1181 GTKGTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGP 1239

Query: 1441 ----------------------GSPGAKGDGGIPGPAGPLGPPGP------------PGL 1466
                                  G PG  G+ G PGPAGP GPPGP            PG+
Sbjct: 1240 AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGI 1299

Query: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP---GPPGEVIQP----LPILSSKKTRRHT 1519
            PGP+GPKG++G  G +G  G+ GL G  G P   G PG+V  P     P +  K   R +
Sbjct: 1300 PGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGS 1359

Query: 1520 EGMQAD 1525
             G+Q D
Sbjct: 1360 SGLQGD 1365



 Score =  761 bits (1966), Expect = 0.0
 Identities = 484/1121 (43%), Positives = 553/1121 (49%), Gaps = 141/1121 (12%)

Query: 489  RGPPGPMGLTGRPGPVGGPGS---SGAKGESGDPG---PQGPRGVQGP------------ 530
            RG PGP+G+ G  GP G  GS   SG KGE G PG   P GP+G +GP            
Sbjct: 49   RGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGI 108

Query: 531  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG-----PQGPP 585
            PG  G+PG RG PG DG  G  G  G  G  G+ GL G PG  G +G +G     P    
Sbjct: 109  PGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK 168

Query: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP- 644
            G  GD G+ G DG  GP+G PG  G  G  GP G  G PG PG      P GP GNMG  
Sbjct: 169  GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG------PLGPDGNMGLG 222

Query: 645  -QGEPGPPGQQGNPGPQGLPGPQGPIG----PPGEKGPQGKPGLAGLPGADGPPGHPG-- 697
             QGE G  G  G PGP G P   G +     P G+KG +G+PG  G PG  GPPG PG  
Sbjct: 223  FQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLG 282

Query: 698  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 757
              G+ GEKG  G PG       PGPRG  G++GV+G  G +G+KG  GFPG  G  G++G
Sbjct: 283  TTGEKGEKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 336

Query: 758  DRGEVGQIGP-----------RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 806
             +G++G  GP            G  G  G  G  G  GD G  G  G  G  G+P L G 
Sbjct: 337  QKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGV 396

Query: 807  PGRQGPKGSTGFPGFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG-------------- 850
            PG  GP+G   FPG  G  G  G    G AG PG  G  GP GP G              
Sbjct: 397  PGALGPQG---FPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNK 453

Query: 851  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPG 910
              G  G  G+ GPKG  G  G  G  G     G     G PG  GPPGP G  GLPG  G
Sbjct: 454  ESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKG 513

Query: 911  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE------RGHPGPPGPPGEQGLPGAAG 964
             RG+ G  G  GP G  G+VGP GP+G  G  GE      +G PG  G  G QG  G  G
Sbjct: 514  ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 573

Query: 965  KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG-----GEGPQGPPGPVGS 1019
            + G  G PG  G+ G  G  G +GFPGE+GLPG  G  G  G     G G  G PGP G 
Sbjct: 574  EPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGL 632

Query: 1020 PGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1076
            PG++G  G  G  GLPG  G   P   PG  G  G PG  G  GP G  G+ G  G PG 
Sbjct: 633  PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 692

Query: 1077 AGPAGSPGEDG--DKGEI-GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG------ 1127
            +G  G PG  G     E+ G PG +G KG  G  G PG  GL G +G+PG+ G       
Sbjct: 693  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 752

Query: 1128 -----DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182
                 +G PG +G QG+ G KG  G  G PG  G  G  GL GP GE+G  G  G +G P
Sbjct: 753  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 812

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242
            G PG  GP G  G  G  G PG  G  G  G+KG  G+ G PG   + G+ G KG  G  
Sbjct: 813  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 872

Query: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302
            G  G  G+ G PG  G P   GPKG  G VGF G PG PG PG      + G +G  G P
Sbjct: 873  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG------IPGTRGLKGIP 926

Query: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ---------GEKGAKGEAGAEGPPGKT 1353
            G  G  GPSG AG PG  G RG PG  G    +         G+KG++G AG+ G PG  
Sbjct: 927  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 984

Query: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413
             P G +G AG+PGP GL G PG  G   + G +G+ GPPG MG  GLPGLKG  G  G  
Sbjct: 985  -PRGDKGEAGRPGPPGLPGAPGLPGI--IKGVSGKPGPPGFMGIRGLPGLKGSSGITGFP 1041

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGP 1469
            G P      G  G QG +G  GLPG  G PG KGD G    I G  GP G PG  G  G 
Sbjct: 1042 GMP------GESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1095

Query: 1470 QGP---------KGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
            +G           GNKG  G  G  GD GLPG PG PG  G
Sbjct: 1096 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1136



 Score =  743 bits (1919), Expect = 0.0
 Identities = 484/1132 (42%), Positives = 562/1132 (49%), Gaps = 104/1132 (9%)

Query: 364  PGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL 419
            PG     DI    I+G+    G  G  G KG+  +      + GP G  G   + G PG 
Sbjct: 344  PGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQG----LRGPSGVPGLPALSGVPGA 399

Query: 420  QGPTGPPGDPGDRGPPGRP-----GLPGADGLPGPPG----------TMLM------LPF 458
             GP G PG  GD+G PGR      GLPG DGLPGPPG          T  +       P 
Sbjct: 400  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 459

Query: 459  RYGGDGSKGPT-ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517
              G  G KG   +   +  +        +   GPPG  G  G  G +G PG  GA+G+ G
Sbjct: 460  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 519

Query: 518  DPGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGF---------DG 565
              G QGP G  G   P GP+G  GK+G P     +GMPG+ G  G +GF         DG
Sbjct: 520  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 579

Query: 566  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 625
            +PGLPG  G  G+ G QG PG  G  G+ GE G  GP GLPG   P GL GPRG PG  G
Sbjct: 580  VPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLP-GLPGPRGLPGDKG 637

Query: 626  QPGMAGVDGPPGPKG---------NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG 676
            + G+ G  G PG KG         + GP G PG PG  G  G +GLPG  G  G  G KG
Sbjct: 638  KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 697

Query: 677  PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG-----V 731
              G PGL  LP   G PG  G++G  G  G  G  G  G IG PG  G KGA G      
Sbjct: 698  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAE 757

Query: 732  RGLKGSKGEKGEDGFPGFKGDMGL---KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788
             G  G +G +G  G  GF GD GL   KG  G+ G +GP+GE G  G  G+ G  G PG 
Sbjct: 758  NGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGS 817

Query: 789  SGQAGEKGKLGVPGLPGYPG---RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845
            SG  G KGK G+PG PG+PG     G KG+ G  G PG+  +KG  G+ G PG  G  G 
Sbjct: 818  SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 877

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGP---PGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902
             G  GS G  G     GPKG  G  G    PG PG  G  G +G  G PG  G  GP G+
Sbjct: 878  KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGR 937

Query: 903  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962
             G PG  G RG  G  G   P  P   +  +G  G  G  G  G PGP G  GE G PG 
Sbjct: 938  AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 997

Query: 963  AGKEGAKGDPGP-QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
             G  GA G PG  +G+SGK GP G   F G RGLPG +G+ G+ G  G    PG  GS G
Sbjct: 998  PGLPGAPGLPGIIKGVSGKPGPPG---FMGIRGLPGLKGSSGITGFPGM---PGESGSQG 1051

Query: 1022 ERGSAGTAGPIGLPGRPGPQGPP----GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1077
             RGS G  G  GLPG  G  G      G  G KG PGE G +G  GRDG+ G +G PG  
Sbjct: 1052 IRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNK 1111

Query: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG---PVGAPGIAGGDGEPGPR 1134
            G  G  G  GD G  G PG  G  G +GE G PG  G QG   P+G+PG+ G  G PG  
Sbjct: 1112 GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFP 1171

Query: 1135 GQQGMFGQKGDEGARGFPGPP--GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1192
            G  G+ G  G +G  G PGP   G  G  GLPGP GEKG  G +G +G PG PG RG +G
Sbjct: 1172 GLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKG 1229

Query: 1193 PNGADGPQGPPGSVGSVGGVGEK---GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1249
              G  G QGP G  G+ G        G+PG+ G PG  GE G  GP G  G  G +   G
Sbjct: 1230 DRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQG 1289

Query: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309
              G PG  G PG  GPKG+ G  GF G PG  G  G  G+ G  G  G+ G PG PG PG
Sbjct: 1290 DTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPG 1349

Query: 1310 PSGEAGPPGPPGKRG-------------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1356
              G+AGP G  G +G             PPG  G  G  G  G  G+ GA+GP G  G  
Sbjct: 1350 MKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSK 1409

Query: 1357 GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKG 1405
            G  G  GK GP GL G PG +G+ GLPG  G    +G PG  GP G+PG+ G
Sbjct: 1410 GLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1461



 Score =  668 bits (1723), Expect = 0.0
 Identities = 436/1071 (40%), Positives = 516/1071 (48%), Gaps = 134/1071 (12%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAV-----------VEPGMLV 401
            P  PP+ EF      ET+      +G  G  GE+G KG   +            + G+  
Sbjct: 437  PPGPPSPEF------ETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 490

Query: 402  EGPPG---PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LML 456
             GPPG   P GP G++G PGL+G  G  G  G +GP G PGL G  G  GP G     +L
Sbjct: 491  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 550

Query: 457  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR-----PGPVGGPGSSG 511
                G  G +G   S  +     I +  +  + G PG  GL G      PG  G PG  G
Sbjct: 551  STIQGMPGDRGD--SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPG 608

Query: 512  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---------PGAKGDRG 562
             KG  G PG  G  G+ G PGP G PG +G+ G  G +G+PG          PG+ G  G
Sbjct: 609  EKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 667

Query: 563  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 622
            F G PG PG KG RG  G  G PG  G  G  G  G +    LPG  GPRG  G  G PG
Sbjct: 668  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 727

Query: 623  APGQPGMAGVDGPPGPKGNMGPQG-----EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677
             PG+ G+ G+ G PG  G+ G  G     E G PG+QG  G  G  G  G  G PG KG 
Sbjct: 728  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 787

Query: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737
             GKPGL G  G  G PG PG+ GQ G  G+ GP G +G  G PG  G  G  G  G KG+
Sbjct: 788  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 847

Query: 738  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797
            +G+KG  G    KG  GLKG  G  G +G +G  G  G  G       P  SG  GEKG 
Sbjct: 848  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGL------PALSGPKGEKGS 901

Query: 798  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP--------- 848
            +G  G PG PG  G  G+ G  G PG+ G+ G  G AG PG +G RG  GP         
Sbjct: 902  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 961

Query: 849  ---------RGSRGARGPTGKPGPKGTSGGDGPPGPPGE----------RGPQGPQGPVG 889
                     +GS+G+ G  G PGP+G  G  G PGPPG           +G  G  GP G
Sbjct: 962  MSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPG 1021

Query: 890  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-RGHP 948
            F G +G PG  G  G+ G PG  GE+G QG  G PG  G  G  G  G+ G   E  G P
Sbjct: 1022 FMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSP 1081

Query: 949  GPPGPPGEQGLPGAAGKEGAKGD---PGPQGISGKDGPAGLRGFPGERGLPGA---QGAP 1002
            GP G PGE G  G  G++G  G+   PG +G  GK G +G  G PG  G PG    +G P
Sbjct: 1082 GPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEP 1141

Query: 1003 GLKGGEGPQGPPGPVGSPG---------------------ERGSAGTAGPIGLPGRPGPQ 1041
            GL G  G QG  GP+GSPG                      +G+ GT GP  + G PGP 
Sbjct: 1142 GLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPA 1200

Query: 1042 GPPGPAGEKGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK------GEIGE 1094
            G PGP GEKG PG   G  G  G  G +G  G PG  GPAG PG  G        G+ G+
Sbjct: 1201 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGD 1260

Query: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154
            PG+ G  G++G  GP GPPG  GP    G  G  G PG  G +G    KGD+G  GF G 
Sbjct: 1261 PGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG---PKGDQGIPGFSGL 1317

Query: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG------------- 1201
            PG +GL+G+ G PG  G  G VGP G PG PG +G  GP G+ G QG             
Sbjct: 1318 PGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV 1377

Query: 1202 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1261
            PPG +G     G  G PG  G+PG  G  G+ G KG  G  G+ GP G  GPPGA G PG
Sbjct: 1378 PPGPLGL---PGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1434

Query: 1262 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312
              G +G PG  G PG  GP G PG  GQ    G         +  PP P G
Sbjct: 1435 LPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1485



 Score =  667 bits (1721), Expect = 0.0
 Identities = 420/977 (42%), Positives = 486/977 (49%), Gaps = 115/977 (11%)

Query: 622  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681
            GA G+PG  G+ GP GP      QG  G  G  G  G +G PG  GP GP G+KGP G P
Sbjct: 47   GARGRPGPIGIQGPTGP------QGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVP 100

Query: 682  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741
            G  G+   +G PGHPG+ G  G  G  G  G QG +G+PGP G  G  G  GL G KG K
Sbjct: 101  GFLGI---NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSK 157

Query: 742  GED-----GFPGFKGDMGLKGDRGEVGQIGPRGEDG---PEGPKGRAGPTGDPGPSGQAG 793
            G+       F G KGD GL G  G  G  G  G  G   P GP G  GP G PGP G  G
Sbjct: 158  GDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 217

Query: 794  E-----KGKLGVPGLPGYPGRQGPKGSTG---FPGFPGANGEKGARGVAGKPGPRGQRGP 845
                  +G+ GV G  G PG  GP  STG   F GFP     KG +G  G+PGP+G  G 
Sbjct: 218  NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPKGFPGI 272

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905
            +GP G  G  G TG+ G KG  G  G PGP G  G +G QGP G  G KG  G PG +G 
Sbjct: 273  SGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF 331

Query: 906  PGHPGQRGETGFQGK-----------TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954
             G  GQ+G+ G  G            +G PG  GV G  G  G+ G  G RG  G PG P
Sbjct: 332  QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLP 391

Query: 955  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG----------- 1003
               G+PGA G +G  G  G QG  G+    G  G PG  GLPG  G PG           
Sbjct: 392  ALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 450

Query: 1004 ---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054
                     L+G +GP+G  G  G  G+ G     G +   G PG  GPPGP G  G PG
Sbjct: 451  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 510

Query: 1055 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI------GEPGQKGSKGDKGENG 1108
             KG +G  G  G QGP G PG  GP G  G  G KGE       G PG +G  G +G  G
Sbjct: 511  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 570

Query: 1109 PPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1166
              G PG  G  G PG+ G  GDG  G  G++G+ G  G++G  G PG PG  GL GLPGP
Sbjct: 571  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGP 629

Query: 1167 ---PGEKGENGDVGPMGPPGP---------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1214
               PG+KG++G  G  G PG          PG  GP G  G  G  GP GS G  G  G+
Sbjct: 630  RGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQ 689

Query: 1215 KGEPGEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268
             G  G  G PG PG        G  GP+GE+G  G  G PG  G PG  G PG  G KG 
Sbjct: 690  PGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGA 749

Query: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG------QPGPPGPSGEAGPPGPPGK 1322
             G + F  + G PGE G  G  G  G  G+ G PG      +PG  GP GE G PG PG+
Sbjct: 750  TGDI-FGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 808

Query: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL---RGIPGPVGE 1379
             G PG  G+ G  G KG  G  GA G PG +G  G +G  GK GP G    +G+PG  G 
Sbjct: 809  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 868

Query: 1380 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
             G PG  G  G PG  G  GLP L G  G KG  G  G  G+ G PG  G +G +G+PG+
Sbjct: 869  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 928

Query: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP------KGNKGS---------TGPAGQ 1484
             G  G  G  G PG  G  G PGP G+P P+ P      KG+KGS          GP G 
Sbjct: 929  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 988

Query: 1485 KGDSGLPGPPGSPGPPG 1501
            KG++G PGPPG PG PG
Sbjct: 989  KGEAGRPGPPGLPGAPG 1005



 Score =  607 bits (1564), Expect = e-173
 Identities = 403/940 (42%), Positives = 464/940 (49%), Gaps = 161/940 (17%)

Query: 704  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            EKGA G PGP G  G  GP+G  G+ G+ GLKG      E GFPG  G  G KGD+G +G
Sbjct: 45   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG------ERGFPGLLGPYGPKGDKGPMG 98

Query: 764  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823
              G  G +G  G  G+ GP G PG  G  G +G +G PG  GYPG  GP      PG PG
Sbjct: 99   VPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP------PGLPG 152

Query: 824  ANGEKGA--------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 875
              G KG         +G+ G PG  G  G TGP+G+ G  G  G  GP G  G  GPPGP
Sbjct: 153  QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 212

Query: 876  PGE--------RGPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGF 917
             G         +G +G +G VG PGP GPP           P GK G  G PG +G   F
Sbjct: 213  LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKG---F 269

Query: 918  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE------QGLPGAAGKEGAKGD 971
             G +GPPG  G+    G TGE G  GE+G PG PGP G       QG PG  GK+G  G 
Sbjct: 270  PGISGPPGFPGL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGF 325

Query: 972  PGPQGISGKDGPAGLRGFPG--------------ERGLPGAQGAPGLKGGEGPQGPPGPV 1017
            PG  G  G +G  G  G PG                G PG  G PGLKG EG QG  GP 
Sbjct: 326  PGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPS 385

Query: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPG 1075
            G PG    +G      +PG  GPQG PG  G++G PG    G  G  GRDG+ GP G PG
Sbjct: 386  GVPGLPALSG------VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 439

Query: 1076 PAGP-----------AGSPGEDGDKGEIGEPGQKGSKGDKG----ENGPP--GPPGLQGP 1118
            P  P           +G PG  G++G  G  G KG KGD G    + G P  GPPG  GP
Sbjct: 440  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 499

Query: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG------------LQGLPGP 1166
             G  G+ G  G  G RG +G  G +G  GA G  GP GP G            +QG+PG 
Sbjct: 500  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 559

Query: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224
             G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G  GEKG PG  G P
Sbjct: 560  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 619

Query: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP------PGDDGPKGNPGPVGFPGDP 1278
            G  G  G+ GP+G  G+KG+ G PG  G PG+KG       PG  GP G PG  GFPG  
Sbjct: 620  GN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 678

Query: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQ------PGPPGPSGEAGPPG---PPGKRGPPGAA 1329
            G  G PG  GQ G  G KGE G PG       PG PGP GE G PG    PGK G PG  
Sbjct: 679  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 738

Query: 1330 GAEGRQGEKGAKGEA--------GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG---PVG 1378
            G+ G  G KGA G+         G +G  G TG  G  G +G PG +G+ G PG   P G
Sbjct: 739  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 798

Query: 1379 EQGLPGA---AGQDGPPGPMGP------------PGLPGLKGDPGSKG---EKGHPGLIG 1420
            E+G PG     GQ G PG  GP            PG PG+ G PG KG   +KG PG I 
Sbjct: 799  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 858

Query: 1421 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP------------PGPPGLPG 1468
              G PG +G  G+ GL G +GSPG+ G  G+P  +GP G             PG PG+PG
Sbjct: 859  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 918

Query: 1469 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508
             +G KG  GSTG  G  G +G PG  G  G PG V  P P
Sbjct: 919  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP 958



 Score =  556 bits (1433), Expect = e-158
 Identities = 365/885 (41%), Positives = 417/885 (47%), Gaps = 127/885 (14%)

Query: 365  GVPAETDITETSINGHGAYGEKGQKGEPAVVEP--GMLVEGPPGPAGPAGIMGPPGLQGP 422
            G+P    IT   I   G+YG  G  G P    P     + G PG  G +G  G PG  G 
Sbjct: 646  GLPGSKGITLPCIIP-GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 704

Query: 423  T------GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
                   G PG  G++G PG PGLPG DGLPG  G+        G  GSKG T     A+
Sbjct: 705  VHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSP-------GLPGSKGATGDIFGAE 757

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 536
              A          G  G  GLTG  G +G  G  G KG  G PG  GP+G +G PG  G+
Sbjct: 758  NGA---------PGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 808

Query: 537  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP------------ 584
             G+ G PG+ G  G+ G+ G  G  GF G+ G PG KG RG++GP G             
Sbjct: 809  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 868

Query: 585  PGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMAGVDGPPGP 638
            PG PG  G++G  G  G  GLP  +GP+G       +G  G PG PG PG  G+ G PG 
Sbjct: 869  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 928

Query: 639  KGNMGPQGEPGPPGQQG---NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695
             G MGP G  G PG++G   NPGP G+P P+ P+     KG +G  G AG  G  GP   
Sbjct: 929  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGP--- 985

Query: 696  PGKEGQSGEKGALGPPGPQGPIGYPGPRGV----------KGADGVRGLKGSKGEKGEDG 745
                   G+KG  G PGP G  G PG  G+           G  G+RGL G KG  G  G
Sbjct: 986  ------RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1039

Query: 746  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA-------GPTGDPGPSGQAGEKGK- 797
            FPG  G+ G +G RG  G  G  G  G +G  G+        GP G PG SG  G KG+ 
Sbjct: 1040 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1099

Query: 798  -----LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852
                 +G PG  G  G+ G  G  G PG PG  G  G RG  G PG  G +G  GP GS 
Sbjct: 1100 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1159

Query: 853  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-----GPVGFPGPKGPP-------GPP 900
            G  GP G PG  G  G +G PG  G  G  GP      GP G PGPKG         G P
Sbjct: 1160 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1219

Query: 901  GKDGLPGHPGQRGETGFQGKTGPPG------PGGVVGPQGPTGETGPIGERGHP---GPP 951
            GK GL G  G RG  G QG  G PG      P  + G  G  G  G  GERG P   GPP
Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1279

Query: 952  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1011
            GPPG     G  G  G  G PGP+G  G  G  G  G PGE GL G +G PG  G  G  
Sbjct: 1280 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1339

Query: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QGPPGPAGEKGAPGEKGPQGPAGR 1064
            GPPG  G PG +G AG  G  GL G PG        Q PPGP    G PG  G  G  G 
Sbjct: 1340 GPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPL---GLPGIDGIPGLTGD 1396

Query: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1124
             G QGPVGL G  G  G PG+DG  G  G PG  G          PG PGLQGP   PG 
Sbjct: 1397 PGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGD---------PGLPGLQGP---PGF 1444

Query: 1125 AGGDGEPGPRGQQGMFGQKGDEG------ARGFPGPPGPIGLQGL 1163
             G  G+ GP G  GM GQ    G      ++    PP PIG+  L
Sbjct: 1445 EGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQL 1489



 Score =  504 bits (1299), Expect = e-142
 Identities = 336/831 (40%), Positives = 377/831 (45%), Gaps = 164/831 (19%)

Query: 827  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 886
            E  A G      P G +  +G       +G  G+PGP G  G  GP G  G  G  G +G
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 77

Query: 887  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG 946
              GFPG  GP GP G  G  G PG  G  G  G  G PGP    GP G  G  G  G  G
Sbjct: 78   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPR---GPPGLDGCNGTQGAVG 134

Query: 947  HPGPPGPPGEQGLPGAAGKEGAKGDP--GPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1004
             PGP G PG  G PG  G++G+KGDP   P    G  G  GL   PG  G+ G QGAPG 
Sbjct: 135  FPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL---PGLDGITGPQGAPGF 191

Query: 1005 KGGEGPQGPPGPVGSPGERGSAGTAGPIGL-----------PGRPGPQGPPGPAGE---- 1049
             G  GP GPPG  G PG  G  G  G +GL            G PGP GPP   GE    
Sbjct: 192  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 251

Query: 1050 ---KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1106
               KG  G KG  GP G  G+ GP G PG  G  G  GE G+KG  G PG +G  G +G 
Sbjct: 252  GFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 310

Query: 1107 NGPPGPPGLQGPVGAPGIAG--------GD------------------GEPGPRGQQGMF 1140
             GPPG  G +G +G PG+ G        GD                  G PG  G  G+ 
Sbjct: 311  QGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLP 370

Query: 1141 GQKGDEGARGFPGP------------PGPIGLQGLPGPPGEKGENGDV------------ 1176
            G KGDEG +G  GP            PG +G QG PG  G++G  G              
Sbjct: 371  GLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 430

Query: 1177 --GPMGPPGPPGP-----------------RGPQGPNGADGPQGPPGSVGSV---GGVGE 1214
              GP GPPGPP P                 RG QGP G  G +G  G  G     GGV  
Sbjct: 431  LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 490

Query: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK-------- 1266
             G PGE G PGP G  G+ G KG RG++G  G  G AG PG  GP G  GPK        
Sbjct: 491  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 550

Query: 1267 ----------------------GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
                                  G PG  G PG PG PG PG  GQ G  G+KG  G PG+
Sbjct: 551  STIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGE 609

Query: 1305 PGPPGPSGEAGP--PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQ 1359
             G PGP G  G   PG PG RG PG  G +G  G++G  G  G   P   PG  GP G  
Sbjct: 610  KGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFP 669

Query: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---------GPPGLPGLKGDPGSK 1410
            G  G PGP+G RG+PG  G+ G  G+ G+ G PG +         GP G  GL G PG  
Sbjct: 670  GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP 729

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGD-----RGLPGTQ---------------GSPGAKGDGG 1450
            G+ G PG+IG  G PG +G  GD      G PG Q               G PG KG  G
Sbjct: 730  GKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 789

Query: 1451 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
             PG  GP G  G PG PG  G  G  GS+GP G KG SGLPG PG PG  G
Sbjct: 790  KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 840



 Score =  442 bits (1138), Expect = e-123
 Identities = 288/707 (40%), Positives = 334/707 (47%), Gaps = 143/707 (20%)

Query: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995
            T E    GE+ +  P G     G      ++GA+G PGP GI G  GP G  G  G  GL
Sbjct: 16   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 75

Query: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055
             G +G PGL G  GP+G  GP+G PG  G  G  G    PG+PGP+GPPG  G  G  G 
Sbjct: 76   KGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH---PGQPGPRGPPGLDGCNGTQGA 132

Query: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113
             G  GP G  G+ GP GLPG  G  G P       KG  G+PG  G  G  G  G PG P
Sbjct: 133  VGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFP 192

Query: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMF-----GQKGDEGARGFPGP-------------- 1154
            G  GP G PG+ G  G PGP G  G       G+KG +G  G PGP              
Sbjct: 193  GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMG 252

Query: 1155 -----------PGPIGLQGLPGPP-----GEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198
                       PGP G  G+ GPP     G  GE G+ G  G PG PGPRGP G  G  G
Sbjct: 253  FPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQG 312

Query: 1199 PQGPPGSVGSVG--------GV-GEKGE---PGE-----------AGNPGPPGEAGVGGP 1235
            P G  G  G++G        G+ G+KG+   PG            +GNPG PG  G+ G 
Sbjct: 313  PPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGL 372

Query: 1236 KGERGEKGEAGP------PGAAGPPGAKGP---PGDDGPKGNPGPV-----------GFP 1275
            KG+ G +G  GP      P  +G PGA GP   PG  G +GNPG             G P
Sbjct: 373  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 432

Query: 1276 GDPGPPGEPGP-----------AGQDGVGGDKGEDGDPGQPGPPGPSG---------EAG 1315
            G PGPPG P P           +G  G+ G++G  G+ G  G  G SG           G
Sbjct: 433  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 492

Query: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQGPAGKPGP----- 1367
            PPG PG  GP G  G  G +G +G +G  GA+GP   PG  GP+GP GP GK G      
Sbjct: 493  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 552

Query: 1368 -EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-----------PGSKGEKGH 1415
             +G+ G  G  G QG  G  G+ G  G  G PGLPGL GD           PG  GEKGH
Sbjct: 553  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 612

Query: 1416 P--------GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG---DGGIPGPAGPLGPPGPP 1464
            P        GL GL GP G  G+KG  GLPG QG PG+KG      IPG  GP G PG P
Sbjct: 613  PGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTP 672

Query: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGP---------PGSPGPPGE 1502
            G PGP+G +G  G+ G  G  G  G PG          PG PGP GE
Sbjct: 673  GFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGE 719



 Score =  374 bits (959), Expect = e-103
 Identities = 238/548 (43%), Positives = 277/548 (50%), Gaps = 78/548 (14%)

Query: 1046 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP---AGSPGEDGDKGEIGEPGQKGSKG 1102
            P G +   G        G  G  GP+G+ GP GP    GS G  G KGE G PG  G  G
Sbjct: 30   PCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG 89

Query: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1162
             KG+ GP G PG    +G  GI G  G+PGPRG  G+ G  G +GA GFPGP G  GL G
Sbjct: 90   PKGDKGPMGVPGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLG 146

Query: 1163 LPGPPGEKGENGDVGPMGPPGP-PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1221
             PG PG+KG  GD  P+  PG   G +G  G  G DG  GP G+ G  G VG  G PG  
Sbjct: 147  PPGLPGQKGSKGD--PVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQ 204

Query: 1222 GNPGPPGEAGVGGP-----KGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNP 1269
            G PGPPG  G  G      +GE+G KG+ G PG AGPP + G       P G  G KG P
Sbjct: 205  GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 264

Query: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329
            GP GFPG  GPPG PG  G  G  G+KGE G PG PGP GP G  G  GPPG++G  G  
Sbjct: 265  GPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTL 323

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGK-----------TGPVGPQGPAGKPGPEGLRGIPGPVG 1378
            G  G  G +G +G+ G  G PG            +G  G  G  G PG +G  GI G  G
Sbjct: 324  GFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRG 383

Query: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE-----KGHPGLIGLIGPP-------- 1425
              G+PG     G PG +GP G PGLKGD G+ G       G PG  GL GPP        
Sbjct: 384  PSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSP 443

Query: 1426 ------------------GEQGEKGDRGLPGTQGSPG-AKGDGGIP--GPAGPLGPPGP- 1463
                              GEQG KG+ GL G +G  G    DGG+P  GP G  GPPGP 
Sbjct: 444  EFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPW 503

Query: 1464 --PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521
               GLPG +G +G++GS G  G  G  GL GP G  GP G+  +  PILS+       +G
Sbjct: 504  GLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK--KGEPILST------IQG 555

Query: 1522 MQADADDN 1529
            M  D  D+
Sbjct: 556  MPGDRGDS 563



 Score =  103 bits (258), Expect = 1e-21
 Identities = 73/183 (39%), Positives = 83/183 (45%), Gaps = 27/183 (14%)

Query: 1343 EAGAEGPPGKTGPVGPQGPAGKPG--PE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG 1399
            E  A G      P G Q  +G     PE G RG PGP+G QG            P GP G
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQG------------PTGPQG 65

Query: 1400 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1459
              G  G  G KGE+G PGL+G  GP G++G           G PG  G  GIPG  G  G
Sbjct: 66   FTGSTGLSGLKGERGFPGLLGPYGPKGDKGP---------MGVPGFLGINGIPGHPGQPG 116

Query: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1519
            P GPPGL G  G +G  G  GP G  G   L GPPG PG  G    P+    S K  +  
Sbjct: 117  PRGPPGLDGCNGTQGAVGFPGPDGYPG---LLGPPGLPGQKGSKGDPVLAPGSFKGMKGD 173

Query: 1520 EGM 1522
             G+
Sbjct: 174  PGL 176


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  830 bits (2145), Expect = 0.0
 Identities = 535/1293 (41%), Positives = 632/1293 (48%), Gaps = 175/1293 (13%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G  G+KG KG+P V+ PG       G  G  G+ G  G+ GP G PG PG  GP G PGL
Sbjct: 148  GLPGQKGSKGDP-VLAPGSF----KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGL 202

Query: 441  PGADGLPGPPGTMLMLPFRYGGD----------GSKGPTISAQEAQAQAILQQARIALRG 490
             G  G PGP G    +   + G+          G  GP  S  E +      + +   +G
Sbjct: 203  QGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKGSKG 261

Query: 491  PPGPMGLTGRPGPVGGPG--SSGAKGESGD------PGPQGP---RGVQGPPGPTGKPGK 539
             PGP G  G  GP G PG  ++G KGE G+      PGP+GP    GVQGPPG  GK G 
Sbjct: 262  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 321

Query: 540  RGRPGADGGRGMPGEPG-----------------AKGDRGFDGLPGLPGDKGHRGERGPQ 582
             G PG +G +G+ G+ G                   G+ G  G+PGLPG KG  G +G +
Sbjct: 322  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 381

Query: 583  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 642
            GP G PG   + G  G +GP+G PG  G +G  G R T GA G PG  G+ GPPGP G  
Sbjct: 382  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPP 440

Query: 643  GPQ-----------GEPGPPGQQGNPGPQGLPGPQGP------------IGPPGEKGPQG 679
             P+           G PG  G+QG  G  GL G +G              GPPGE GP G
Sbjct: 441  SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 500

Query: 680  KPGLAGLPGADGPPGHPGKEGQSGEKGA------LGPPGPQGPIGYP------GPRGVKG 727
              GL GLPG  G  G  G  G  G  GA      LGP GP+G  G P      G  G +G
Sbjct: 501  PWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRG 560

Query: 728  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787
              G +G +G  GE G+DG PG  G  GL GD G+ G  G +G  G  G KG  GP G PG
Sbjct: 561  DSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG 619

Query: 788  --------PSGQAGEKGKLGVPG---LPG---------YPGRQGPKGSTGFPGFPGANGE 827
                    P G  G+KGK G+PG   LPG          PG  GP G  G PGFPG  G 
Sbjct: 620  NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 679

Query: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887
            +G  G  G+PG  G +G  G  G        G PGP+G  G  G PG PG+ G  G  G 
Sbjct: 680  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 739

Query: 888  VGFPGPKGP-----------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 936
             G PG KG            PG  G  GL GH G  G++G  G  G  G  G++GP+G  
Sbjct: 740  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 799

Query: 937  GETGPIGERGHPGPPGPPG------EQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---R 987
            G  G  G+ G PG PG  G      + GLPGA G  G  G PG +G  GK GP G    +
Sbjct: 800  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 859

Query: 988  GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1047
            G PG +GLPG  G  GLKG  G  G  G     G +G  G+ G +G PG PG  G PG  
Sbjct: 860  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 919

Query: 1048 GEKGAPGEKGPQGPAGRDGVQG---------PVGLPGPAGPAGS---PGEDGDKGEIGEP 1095
            G KG PG  G  GP+GR G  G         PVG+P P  P  +    G+ G +G  G  
Sbjct: 920  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 979

Query: 1096 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-DGEPGP---RGQQGMFGQKGDEGARGF 1151
            G  G +GDKGE G PGPPGL G  G PGI  G  G+PGP    G +G+ G KG  G  GF
Sbjct: 980  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1039

Query: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPG 1204
            PG PG  G QG+ G PG  G +G  G  G         G PGP+G  G +G  G +G  G
Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099

Query: 1205 SVGSVGGVGEKGEPG------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---PG 1255
             +G++G  G KGE G      + G PG PG  GV G +GE G  G +G  GA GP   PG
Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159

Query: 1256 AKGP------PGDDGPKGNPGPVGFPGDPGPP--GEPGPAGQDGVGGDKGEDG-DPGQPG 1306
              GP      PG  G  G PG  G  G PGP   G PGPAG  G  G+KG  G   G PG
Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1219

Query: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366
             PG  G+ G  G PG +GP G  GA G        G+ G  G PG  G  G  GPAG PG
Sbjct: 1220 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPG 1279

Query: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---IG 1423
            P G     G  G+ G PG  G  GP G  G PG  GL G+ G KG +G PG +G    +G
Sbjct: 1280 PPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1339

Query: 1424 PPGEQGEKGDRGLPGTQGSPGAKGDGG-------IPGPAGPLGPPGPPGLPGPQGPKGNK 1476
            PPG+ G  G +G  G +GS G +GD G       +  P GPLG PG  G+PG  G  G +
Sbjct: 1340 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ 1399

Query: 1477 GSTGPAGQKGDSGLPG---PPGSPGPPGEVIQP 1506
            G  G  G KG  G+PG   P G PGPPG +  P
Sbjct: 1400 GPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDP 1432



 Score =  819 bits (2116), Expect = 0.0
 Identities = 548/1326 (41%), Positives = 635/1326 (47%), Gaps = 209/1326 (15%)

Query: 381  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 440
            G+ G  G KGE     PG+L  GP GP G  G MG PG  G  G PG PG  GP G PGL
Sbjct: 67   GSTGLSGLKGERGF--PGLL--GPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGL 122

Query: 441  ------PGADGLPGPPG--TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 492
                   GA G PGP G   +L  P   G  GSKG  + A  +            ++G P
Sbjct: 123  DGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK---------GMKGDP 173

Query: 493  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK--RGRPGADGGRG 550
            G  GL G  GP G PG  GA G +G PG QGP G  GP GP G  G   +G  G  G  G
Sbjct: 174  GLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVG 233

Query: 551  MP---GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP---GPPGDDGM--RGEDGEIGP 602
            +P   G P + G+  F G P   G KG +GE GP+G P   GPPG  G+   GE GE G 
Sbjct: 234  LPGPAGPPPSTGELEFMGFP--KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGE 291

Query: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE------PGP------ 650
            +G+PG  GPRG +G  G  G PGQ G  G  G PG  G  G +G+      PGP      
Sbjct: 292  KGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDI 351

Query: 651  -----PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG---LAGLPGADGPPGHPGKEGQS 702
                  G  G+PG  GLPG +G  G  G +GP G PG   L+G+PGA GP G PG +G  
Sbjct: 352  DGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQ 411

Query: 703  GEKGAL--------------GPPGPQGP--------------IGYPGPRGVKGADGVRGL 734
            G  G                GPPGP GP               G+PG RG +G  G  GL
Sbjct: 412  GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGL 471

Query: 735  KGSKGEK---------------GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779
            KG KG+                GE G PG  G +GL G +G  G  G  G  GP G  G 
Sbjct: 472  KGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL 531

Query: 780  AGPTGDPGPSGQAGE---------------KGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
             GP G  GP G+ GE                G  G  G+ G PG+ G  G  G PG PG 
Sbjct: 532  VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD 591

Query: 825  NGE--KGARGVAGKPGPRGQRGPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG 880
             G+   G +G+ G PG +G  GP G    G  G  GP G PG KG  G  G  G PG +G
Sbjct: 592  GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG 651

Query: 881  ------PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 934
                    G  GP GFPG  G PGP G  GLPG PGQ G +G +G+  P  PG V  P+ 
Sbjct: 652  ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE--PGSPGLVHLPEL 709

Query: 935  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----ISGKDGPAGLRGF 989
            P G  GP GE+G PG PG PG+ GLPG  G  G  G  G  G      +G  G  GL+G 
Sbjct: 710  P-GFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGL 768

Query: 990  PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
             G +G  G  G PGLK   G  G PG +G  GERGS GT G +G PG PG  GP G  G+
Sbjct: 769  TGHKGFLGDSGLPGLK---GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 825

Query: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1109
             G PG  G  G +G  G +G  G  GP G     G  G KG  G PG  G KG  G  G 
Sbjct: 826  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 885

Query: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1169
             G P L GP G  G  G  G PG  G  G+    G  G +G PG  G +G  G  G PGE
Sbjct: 886  AGLPALSGPKGEKGSVGFVGFPGIPGLPGI---PGTRGLKGIPGSTGKMGPSGRAGTPGE 942

Query: 1170 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229
            KG+ G+ GP+   G P PR P       G +G  GS GS G  G +G+ GEAG PGPPG 
Sbjct: 943  KGDRGNPGPV---GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGL 999

Query: 1230 AGVGGPKG-ERGEKGEAGPP---GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285
             G  G  G  +G  G+ GPP   G  G PG KG  G  G  G PG  G  G  G PG PG
Sbjct: 1000 PGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1059

Query: 1286 PAGQDGVGGDKGE----DGDPGQPGPPGPSGEAGPPGP---------PGKRGPPGAAGAE 1332
             +G  G+ GD G+     G PG  G PG SG  G  G          PG +G  G  G  
Sbjct: 1060 ASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVS 1119

Query: 1333 GRQGEKGA---------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1383
            G  G  GA         +GE G  G  G  G +GP G  G  GP+G  G PG  G  GLP
Sbjct: 1120 GDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLP 1179

Query: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL-IGLIGPPGEQGEKGDRGLPGTQ-- 1440
            G  G  G PGP    G+PG  G PG KGEKG+PG+ IG  G PG +G+KGDRG PG Q  
Sbjct: 1180 GTKGTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGP 1238

Query: 1441 ----------------------GSPGAKGDGGIPGPAGPLGPPGP------------PGL 1466
                                  G PG  G+ G PGPAGP GPPGP            PG+
Sbjct: 1239 AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGI 1298

Query: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP---GPPGEVIQP----LPILSSKKTRRHT 1519
            PGP+GPKG++G  G +G  G+ GL G  G P   G PG+V  P     P +  K   R +
Sbjct: 1299 PGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGS 1358

Query: 1520 EGMQAD 1525
             G+Q D
Sbjct: 1359 SGLQGD 1364



 Score =  761 bits (1966), Expect = 0.0
 Identities = 484/1121 (43%), Positives = 553/1121 (49%), Gaps = 141/1121 (12%)

Query: 489  RGPPGPMGLTGRPGPVGGPGS---SGAKGESGDPG---PQGPRGVQGP------------ 530
            RG PGP+G+ G  GP G  GS   SG KGE G PG   P GP+G +GP            
Sbjct: 48   RGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGI 107

Query: 531  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG-----PQGPP 585
            PG  G+PG RG PG DG  G  G  G  G  G+ GL G PG  G +G +G     P    
Sbjct: 108  PGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK 167

Query: 586  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP- 644
            G  GD G+ G DG  GP+G PG  G  G  GP G  G PG PG      P GP GNMG  
Sbjct: 168  GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG------PLGPDGNMGLG 221

Query: 645  -QGEPGPPGQQGNPGPQGLPGPQGPIG----PPGEKGPQGKPGLAGLPGADGPPGHPG-- 697
             QGE G  G  G PGP G P   G +     P G+KG +G+PG  G PG  GPPG PG  
Sbjct: 222  FQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLG 281

Query: 698  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 757
              G+ GEKG  G PG       PGPRG  G++GV+G  G +G+KG  GFPG  G  G++G
Sbjct: 282  TTGEKGEKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 335

Query: 758  DRGEVGQIGP-----------RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 806
             +G++G  GP            G  G  G  G  G  GD G  G  G  G  G+P L G 
Sbjct: 336  QKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGV 395

Query: 807  PGRQGPKGSTGFPGFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG-------------- 850
            PG  GP+G   FPG  G  G  G    G AG PG  G  GP GP G              
Sbjct: 396  PGALGPQG---FPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNK 452

Query: 851  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPG 910
              G  G  G+ GPKG  G  G  G  G     G     G PG  GPPGP G  GLPG  G
Sbjct: 453  ESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKG 512

Query: 911  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE------RGHPGPPGPPGEQGLPGAAG 964
             RG+ G  G  GP G  G+VGP GP+G  G  GE      +G PG  G  G QG  G  G
Sbjct: 513  ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 572

Query: 965  KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG-----GEGPQGPPGPVGS 1019
            + G  G PG  G+ G  G  G +GFPGE+GLPG  G  G  G     G G  G PGP G 
Sbjct: 573  EPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGL 631

Query: 1020 PGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1076
            PG++G  G  G  GLPG  G   P   PG  G  G PG  G  GP G  G+ G  G PG 
Sbjct: 632  PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 691

Query: 1077 AGPAGSPGEDG--DKGEI-GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG------ 1127
            +G  G PG  G     E+ G PG +G KG  G  G PG  GL G +G+PG+ G       
Sbjct: 692  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 751

Query: 1128 -----DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1182
                 +G PG +G QG+ G KG  G  G PG  G  G  GL GP GE+G  G  G +G P
Sbjct: 752  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 811

Query: 1183 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1242
            G PG  GP G  G  G  G PG  G  G  G+KG  G+ G PG   + G+ G KG  G  
Sbjct: 812  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 871

Query: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1302
            G  G  G+ G PG  G P   GPKG  G VGF G PG PG PG      + G +G  G P
Sbjct: 872  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG------IPGTRGLKGIP 925

Query: 1303 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ---------GEKGAKGEAGAEGPPGKT 1353
            G  G  GPSG AG PG  G RG PG  G    +         G+KG++G AG+ G PG  
Sbjct: 926  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 983

Query: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1413
             P G +G AG+PGP GL G PG  G   + G +G+ GPPG MG  GLPGLKG  G  G  
Sbjct: 984  -PRGDKGEAGRPGPPGLPGAPGLPGI--IKGVSGKPGPPGFMGIRGLPGLKGSSGITGFP 1040

Query: 1414 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGP 1469
            G P      G  G QG +G  GLPG  G PG KGD G    I G  GP G PG  G  G 
Sbjct: 1041 GMP------GESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1094

Query: 1470 QGP---------KGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
            +G           GNKG  G  G  GD GLPG PG PG  G
Sbjct: 1095 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1135



 Score =  743 bits (1919), Expect = 0.0
 Identities = 484/1132 (42%), Positives = 562/1132 (49%), Gaps = 104/1132 (9%)

Query: 364  PGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL 419
            PG     DI    I+G+    G  G  G KG+  +      + GP G  G   + G PG 
Sbjct: 343  PGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQG----LRGPSGVPGLPALSGVPGA 398

Query: 420  QGPTGPPGDPGDRGPPGRP-----GLPGADGLPGPPG----------TMLM------LPF 458
             GP G PG  GD+G PGR      GLPG DGLPGPPG          T  +       P 
Sbjct: 399  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 458

Query: 459  RYGGDGSKGPT-ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517
              G  G KG   +   +  +        +   GPPG  G  G  G +G PG  GA+G+ G
Sbjct: 459  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 518

Query: 518  DPGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGF---------DG 565
              G QGP G  G   P GP+G  GK+G P     +GMPG+ G  G +GF         DG
Sbjct: 519  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 578

Query: 566  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 625
            +PGLPG  G  G+ G QG PG  G  G+ GE G  GP GLPG   P GL GPRG PG  G
Sbjct: 579  VPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLP-GLPGPRGLPGDKG 636

Query: 626  QPGMAGVDGPPGPKG---------NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG 676
            + G+ G  G PG KG         + GP G PG PG  G  G +GLPG  G  G  G KG
Sbjct: 637  KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 696

Query: 677  PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG-----V 731
              G PGL  LP   G PG  G++G  G  G  G  G  G IG PG  G KGA G      
Sbjct: 697  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAE 756

Query: 732  RGLKGSKGEKGEDGFPGFKGDMGL---KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788
             G  G +G +G  G  GF GD GL   KG  G+ G +GP+GE G  G  G+ G  G PG 
Sbjct: 757  NGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGS 816

Query: 789  SGQAGEKGKLGVPGLPGYPG---RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845
            SG  G KGK G+PG PG+PG     G KG+ G  G PG+  +KG  G+ G PG  G  G 
Sbjct: 817  SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 876

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGP---PGPPGERGPQGPQGPVGFPGPKGPPGPPGK 902
             G  GS G  G     GPKG  G  G    PG PG  G  G +G  G PG  G  GP G+
Sbjct: 877  KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGR 936

Query: 903  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 962
             G PG  G RG  G  G   P  P   +  +G  G  G  G  G PGP G  GE G PG 
Sbjct: 937  AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 996

Query: 963  AGKEGAKGDPGP-QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1021
             G  GA G PG  +G+SGK GP G   F G RGLPG +G+ G+ G  G    PG  GS G
Sbjct: 997  PGLPGAPGLPGIIKGVSGKPGPPG---FMGIRGLPGLKGSSGITGFPGM---PGESGSQG 1050

Query: 1022 ERGSAGTAGPIGLPGRPGPQGPP----GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1077
             RGS G  G  GLPG  G  G      G  G KG PGE G +G  GRDG+ G +G PG  
Sbjct: 1051 IRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNK 1110

Query: 1078 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG---PVGAPGIAGGDGEPGPR 1134
            G  G  G  GD G  G PG  G  G +GE G PG  G QG   P+G+PG+ G  G PG  
Sbjct: 1111 GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFP 1170

Query: 1135 GQQGMFGQKGDEGARGFPGPP--GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1192
            G  G+ G  G +G  G PGP   G  G  GLPGP GEKG  G +G +G PG PG RG +G
Sbjct: 1171 GLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKG 1228

Query: 1193 PNGADGPQGPPGSVGSVGGVGEK---GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1249
              G  G QGP G  G+ G        G+PG+ G PG  GE G  GP G  G  G +   G
Sbjct: 1229 DRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQG 1288

Query: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309
              G PG  G PG  GPKG+ G  GF G PG  G  G  G+ G  G  G+ G PG PG PG
Sbjct: 1289 DTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPG 1348

Query: 1310 PSGEAGPPGPPGKRG-------------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1356
              G+AGP G  G +G             PPG  G  G  G  G  G+ GA+GP G  G  
Sbjct: 1349 MKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSK 1408

Query: 1357 GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKG 1405
            G  G  GK GP GL G PG +G+ GLPG  G    +G PG  GP G+PG+ G
Sbjct: 1409 GLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1460



 Score =  668 bits (1723), Expect = 0.0
 Identities = 436/1071 (40%), Positives = 516/1071 (48%), Gaps = 134/1071 (12%)

Query: 354  PTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAV-----------VEPGMLV 401
            P  PP+ EF      ET+      +G  G  GE+G KG   +            + G+  
Sbjct: 436  PPGPPSPEF------ETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 489

Query: 402  EGPPG---PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LML 456
             GPPG   P GP G++G PGL+G  G  G  G +GP G PGL G  G  GP G     +L
Sbjct: 490  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 549

Query: 457  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR-----PGPVGGPGSSG 511
                G  G +G   S  +     I +  +  + G PG  GL G      PG  G PG  G
Sbjct: 550  STIQGMPGDRGD--SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPG 607

Query: 512  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---------PGAKGDRG 562
             KG  G PG  G  G+ G PGP G PG +G+ G  G +G+PG          PG+ G  G
Sbjct: 608  EKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 666

Query: 563  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 622
            F G PG PG KG RG  G  G PG  G  G  G  G +    LPG  GPRG  G  G PG
Sbjct: 667  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 726

Query: 623  APGQPGMAGVDGPPGPKGNMGPQG-----EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677
             PG+ G+ G+ G PG  G+ G  G     E G PG+QG  G  G  G  G  G PG KG 
Sbjct: 727  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 786

Query: 678  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737
             GKPGL G  G  G PG PG+ GQ G  G+ GP G +G  G PG  G  G  G  G KG+
Sbjct: 787  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 846

Query: 738  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797
            +G+KG  G    KG  GLKG  G  G +G +G  G  G  G       P  SG  GEKG 
Sbjct: 847  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGL------PALSGPKGEKGS 900

Query: 798  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP--------- 848
            +G  G PG PG  G  G+ G  G PG+ G+ G  G AG PG +G RG  GP         
Sbjct: 901  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 960

Query: 849  ---------RGSRGARGPTGKPGPKGTSGGDGPPGPPGE----------RGPQGPQGPVG 889
                     +GS+G+ G  G PGP+G  G  G PGPPG           +G  G  GP G
Sbjct: 961  MSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPG 1020

Query: 890  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-RGHP 948
            F G +G PG  G  G+ G PG  GE+G QG  G PG  G  G  G  G+ G   E  G P
Sbjct: 1021 FMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSP 1080

Query: 949  GPPGPPGEQGLPGAAGKEGAKGD---PGPQGISGKDGPAGLRGFPGERGLPGA---QGAP 1002
            GP G PGE G  G  G++G  G+   PG +G  GK G +G  G PG  G PG    +G P
Sbjct: 1081 GPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEP 1140

Query: 1003 GLKGGEGPQGPPGPVGSPG---------------------ERGSAGTAGPIGLPGRPGPQ 1041
            GL G  G QG  GP+GSPG                      +G+ GT GP  + G PGP 
Sbjct: 1141 GLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPA 1199

Query: 1042 GPPGPAGEKGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK------GEIGE 1094
            G PGP GEKG PG   G  G  G  G +G  G PG  GPAG PG  G        G+ G+
Sbjct: 1200 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGD 1259

Query: 1095 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1154
            PG+ G  G++G  GP GPPG  GP    G  G  G PG  G +G    KGD+G  GF G 
Sbjct: 1260 PGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG---PKGDQGIPGFSGL 1316

Query: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG------------- 1201
            PG +GL+G+ G PG  G  G VGP G PG PG +G  GP G+ G QG             
Sbjct: 1317 PGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV 1376

Query: 1202 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1261
            PPG +G     G  G PG  G+PG  G  G+ G KG  G  G+ GP G  GPPGA G PG
Sbjct: 1377 PPGPLGL---PGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1433

Query: 1262 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312
              G +G PG  G PG  GP G PG  GQ    G         +  PP P G
Sbjct: 1434 LPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1484



 Score =  667 bits (1721), Expect = 0.0
 Identities = 420/977 (42%), Positives = 486/977 (49%), Gaps = 115/977 (11%)

Query: 622  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681
            GA G+PG  G+ GP GP      QG  G  G  G  G +G PG  GP GP G+KGP G P
Sbjct: 46   GARGRPGPIGIQGPTGP------QGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVP 99

Query: 682  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741
            G  G+   +G PGHPG+ G  G  G  G  G QG +G+PGP G  G  G  GL G KG K
Sbjct: 100  GFLGI---NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSK 156

Query: 742  GED-----GFPGFKGDMGLKGDRGEVGQIGPRGEDG---PEGPKGRAGPTGDPGPSGQAG 793
            G+       F G KGD GL G  G  G  G  G  G   P GP G  GP G PGP G  G
Sbjct: 157  GDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 216

Query: 794  E-----KGKLGVPGLPGYPGRQGPKGSTG---FPGFPGANGEKGARGVAGKPGPRGQRGP 845
                  +G+ GV G  G PG  GP  STG   F GFP     KG +G  G+PGP+G  G 
Sbjct: 217  NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPKGFPGI 271

Query: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905
            +GP G  G  G TG+ G KG  G  G PGP G  G +G QGP G  G KG  G PG +G 
Sbjct: 272  SGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF 330

Query: 906  PGHPGQRGETGFQGK-----------TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 954
             G  GQ+G+ G  G            +G PG  GV G  G  G+ G  G RG  G PG P
Sbjct: 331  QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLP 390

Query: 955  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG----------- 1003
               G+PGA G +G  G  G QG  G+    G  G PG  GLPG  G PG           
Sbjct: 391  ALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 449

Query: 1004 ---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054
                     L+G +GP+G  G  G  G+ G     G +   G PG  GPPGP G  G PG
Sbjct: 450  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 509

Query: 1055 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI------GEPGQKGSKGDKGENG 1108
             KG +G  G  G QGP G PG  GP G  G  G KGE       G PG +G  G +G  G
Sbjct: 510  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 569

Query: 1109 PPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1166
              G PG  G  G PG+ G  GDG  G  G++G+ G  G++G  G PG PG  GL GLPGP
Sbjct: 570  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGP 628

Query: 1167 ---PGEKGENGDVGPMGPPGP---------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1214
               PG+KG++G  G  G PG          PG  GP G  G  G  GP GS G  G  G+
Sbjct: 629  RGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQ 688

Query: 1215 KGEPGEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268
             G  G  G PG PG        G  GP+GE+G  G  G PG  G PG  G PG  G KG 
Sbjct: 689  PGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGA 748

Query: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG------QPGPPGPSGEAGPPGPPGK 1322
             G + F  + G PGE G  G  G  G  G+ G PG      +PG  GP GE G PG PG+
Sbjct: 749  TGDI-FGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 807

Query: 1323 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL---RGIPGPVGE 1379
             G PG  G+ G  G KG  G  GA G PG +G  G +G  GK GP G    +G+PG  G 
Sbjct: 808  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 867

Query: 1380 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
             G PG  G  G PG  G  GLP L G  G KG  G  G  G+ G PG  G +G +G+PG+
Sbjct: 868  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 927

Query: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP------KGNKGS---------TGPAGQ 1484
             G  G  G  G PG  G  G PGP G+P P+ P      KG+KGS          GP G 
Sbjct: 928  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 987

Query: 1485 KGDSGLPGPPGSPGPPG 1501
            KG++G PGPPG PG PG
Sbjct: 988  KGEAGRPGPPGLPGAPG 1004



 Score =  607 bits (1564), Expect = e-173
 Identities = 403/940 (42%), Positives = 464/940 (49%), Gaps = 161/940 (17%)

Query: 704  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
            EKGA G PGP G  G  GP+G  G+ G+ GLKG      E GFPG  G  G KGD+G +G
Sbjct: 44   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG------ERGFPGLLGPYGPKGDKGPMG 97

Query: 764  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823
              G  G +G  G  G+ GP G PG  G  G +G +G PG  GYPG  GP      PG PG
Sbjct: 98   VPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP------PGLPG 151

Query: 824  ANGEKGA--------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 875
              G KG         +G+ G PG  G  G TGP+G+ G  G  G  GP G  G  GPPGP
Sbjct: 152  QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 211

Query: 876  PGE--------RGPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGF 917
             G         +G +G +G VG PGP GPP           P GK G  G PG +G   F
Sbjct: 212  LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKG---F 268

Query: 918  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE------QGLPGAAGKEGAKGD 971
             G +GPPG  G+    G TGE G  GE+G PG PGP G       QG PG  GK+G  G 
Sbjct: 269  PGISGPPGFPGL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGF 324

Query: 972  PGPQGISGKDGPAGLRGFPG--------------ERGLPGAQGAPGLKGGEGPQGPPGPV 1017
            PG  G  G +G  G  G PG                G PG  G PGLKG EG QG  GP 
Sbjct: 325  PGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPS 384

Query: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPG 1075
            G PG    +G      +PG  GPQG PG  G++G PG    G  G  GRDG+ GP G PG
Sbjct: 385  GVPGLPALSG------VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 438

Query: 1076 PAGP-----------AGSPGEDGDKGEIGEPGQKGSKGDKG----ENGPP--GPPGLQGP 1118
            P  P           +G PG  G++G  G  G KG KGD G    + G P  GPPG  GP
Sbjct: 439  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 498

Query: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG------------LQGLPGP 1166
             G  G+ G  G  G RG +G  G +G  GA G  GP GP G            +QG+PG 
Sbjct: 499  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 558

Query: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224
             G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G  GEKG PG  G P
Sbjct: 559  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 618

Query: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP------PGDDGPKGNPGPVGFPGDP 1278
            G  G  G+ GP+G  G+KG+ G PG  G PG+KG       PG  GP G PG  GFPG  
Sbjct: 619  GN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 677

Query: 1279 GPPGEPGPAGQDGVGGDKGEDGDPGQ------PGPPGPSGEAGPPG---PPGKRGPPGAA 1329
            G  G PG  GQ G  G KGE G PG       PG PGP GE G PG    PGK G PG  
Sbjct: 678  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 737

Query: 1330 GAEGRQGEKGAKGEA--------GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG---PVG 1378
            G+ G  G KGA G+         G +G  G TG  G  G +G PG +G+ G PG   P G
Sbjct: 738  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 797

Query: 1379 EQGLPGA---AGQDGPPGPMGP------------PGLPGLKGDPGSKG---EKGHPGLIG 1420
            E+G PG     GQ G PG  GP            PG PG+ G PG KG   +KG PG I 
Sbjct: 798  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 857

Query: 1421 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP------------PGPPGLPG 1468
              G PG +G  G+ GL G +GSPG+ G  G+P  +GP G             PG PG+PG
Sbjct: 858  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 917

Query: 1469 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508
             +G KG  GSTG  G  G +G PG  G  G PG V  P P
Sbjct: 918  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP 957



 Score =  556 bits (1433), Expect = e-158
 Identities = 365/885 (41%), Positives = 417/885 (47%), Gaps = 127/885 (14%)

Query: 365  GVPAETDITETSINGHGAYGEKGQKGEPAVVEP--GMLVEGPPGPAGPAGIMGPPGLQGP 422
            G+P    IT   I   G+YG  G  G P    P     + G PG  G +G  G PG  G 
Sbjct: 645  GLPGSKGITLPCIIP-GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 703

Query: 423  T------GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 476
                   G PG  G++G PG PGLPG DGLPG  G+        G  GSKG T     A+
Sbjct: 704  VHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSP-------GLPGSKGATGDIFGAE 756

Query: 477  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 536
              A          G  G  GLTG  G +G  G  G KG  G PG  GP+G +G PG  G+
Sbjct: 757  NGA---------PGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 807

Query: 537  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP------------ 584
             G+ G PG+ G  G+ G+ G  G  GF G+ G PG KG RG++GP G             
Sbjct: 808  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 867

Query: 585  PGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMAGVDGPPGP 638
            PG PG  G++G  G  G  GLP  +GP+G       +G  G PG PG PG  G+ G PG 
Sbjct: 868  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 927

Query: 639  KGNMGPQGEPGPPGQQG---NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695
             G MGP G  G PG++G   NPGP G+P P+ P+     KG +G  G AG  G  GP   
Sbjct: 928  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGP--- 984

Query: 696  PGKEGQSGEKGALGPPGPQGPIGYPGPRGV----------KGADGVRGLKGSKGEKGEDG 745
                   G+KG  G PGP G  G PG  G+           G  G+RGL G KG  G  G
Sbjct: 985  ------RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1038

Query: 746  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA-------GPTGDPGPSGQAGEKGK- 797
            FPG  G+ G +G RG  G  G  G  G +G  G+        GP G PG SG  G KG+ 
Sbjct: 1039 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1098

Query: 798  -----LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852
                 +G PG  G  G+ G  G  G PG PG  G  G RG  G PG  G +G  GP GS 
Sbjct: 1099 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1158

Query: 853  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-----GPVGFPGPKGPP-------GPP 900
            G  GP G PG  G  G +G PG  G  G  GP      GP G PGPKG         G P
Sbjct: 1159 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1218

Query: 901  GKDGLPGHPGQRGETGFQGKTGPPG------PGGVVGPQGPTGETGPIGERGHP---GPP 951
            GK GL G  G RG  G QG  G PG      P  + G  G  G  G  GERG P   GPP
Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1278

Query: 952  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1011
            GPPG     G  G  G  G PGP+G  G  G  G  G PGE GL G +G PG  G  G  
Sbjct: 1279 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1338

Query: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QGPPGPAGEKGAPGEKGPQGPAGR 1064
            GPPG  G PG +G AG  G  GL G PG        Q PPGP    G PG  G  G  G 
Sbjct: 1339 GPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPL---GLPGIDGIPGLTGD 1395

Query: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1124
             G QGPVGL G  G  G PG+DG  G  G PG  G          PG PGLQGP   PG 
Sbjct: 1396 PGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGD---------PGLPGLQGP---PGF 1443

Query: 1125 AGGDGEPGPRGQQGMFGQKGDEG------ARGFPGPPGPIGLQGL 1163
             G  G+ GP G  GM GQ    G      ++    PP PIG+  L
Sbjct: 1444 EGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQL 1488



 Score =  504 bits (1299), Expect = e-142
 Identities = 336/831 (40%), Positives = 377/831 (45%), Gaps = 164/831 (19%)

Query: 827  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 886
            E  A G      P G +  +G       +G  G+PGP G  G  GP G  G  G  G +G
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 76

Query: 887  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG 946
              GFPG  GP GP G  G  G PG  G  G  G  G PGP    GP G  G  G  G  G
Sbjct: 77   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPR---GPPGLDGCNGTQGAVG 133

Query: 947  HPGPPGPPGEQGLPGAAGKEGAKGDP--GPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1004
             PGP G PG  G PG  G++G+KGDP   P    G  G  GL   PG  G+ G QGAPG 
Sbjct: 134  FPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL---PGLDGITGPQGAPGF 190

Query: 1005 KGGEGPQGPPGPVGSPGERGSAGTAGPIGL-----------PGRPGPQGPPGPAGE---- 1049
             G  GP GPPG  G PG  G  G  G +GL            G PGP GPP   GE    
Sbjct: 191  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 250

Query: 1050 ---KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1106
               KG  G KG  GP G  G+ GP G PG  G  G  GE G+KG  G PG +G  G +G 
Sbjct: 251  GFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 309

Query: 1107 NGPPGPPGLQGPVGAPGIAG--------GD------------------GEPGPRGQQGMF 1140
             GPPG  G +G +G PG+ G        GD                  G PG  G  G+ 
Sbjct: 310  QGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLP 369

Query: 1141 GQKGDEGARGFPGP------------PGPIGLQGLPGPPGEKGENGDV------------ 1176
            G KGDEG +G  GP            PG +G QG PG  G++G  G              
Sbjct: 370  GLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 429

Query: 1177 --GPMGPPGPPGP-----------------RGPQGPNGADGPQGPPGSVGSV---GGVGE 1214
              GP GPPGPP P                 RG QGP G  G +G  G  G     GGV  
Sbjct: 430  LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 489

Query: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK-------- 1266
             G PGE G PGP G  G+ G KG RG++G  G  G AG PG  GP G  GPK        
Sbjct: 490  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 549

Query: 1267 ----------------------GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304
                                  G PG  G PG PG PG PG  GQ G  G+KG  G PG+
Sbjct: 550  STIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGE 608

Query: 1305 PGPPGPSGEAGP--PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQ 1359
             G PGP G  G   PG PG RG PG  G +G  G++G  G  G   P   PG  GP G  
Sbjct: 609  KGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFP 668

Query: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---------GPPGLPGLKGDPGSK 1410
            G  G PGP+G RG+PG  G+ G  G+ G+ G PG +         GP G  GL G PG  
Sbjct: 669  GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP 728

Query: 1411 GEKGHPGLIGLIGPPGEQGEKGD-----RGLPGTQ---------------GSPGAKGDGG 1450
            G+ G PG+IG  G PG +G  GD      G PG Q               G PG KG  G
Sbjct: 729  GKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 788

Query: 1451 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501
             PG  GP G  G PG PG  G  G  GS+GP G KG SGLPG PG PG  G
Sbjct: 789  KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 839



 Score =  442 bits (1138), Expect = e-123
 Identities = 288/707 (40%), Positives = 334/707 (47%), Gaps = 143/707 (20%)

Query: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995
            T E    GE+ +  P G     G      ++GA+G PGP GI G  GP G  G  G  GL
Sbjct: 15   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 74

Query: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055
             G +G PGL G  GP+G  GP+G PG  G  G  G    PG+PGP+GPPG  G  G  G 
Sbjct: 75   KGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH---PGQPGPRGPPGLDGCNGTQGA 131

Query: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1113
             G  GP G  G+ GP GLPG  G  G P       KG  G+PG  G  G  G  G PG P
Sbjct: 132  VGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFP 191

Query: 1114 GLQGPVGAPGIAGGDGEPGPRGQQGMF-----GQKGDEGARGFPGP-------------- 1154
            G  GP G PG+ G  G PGP G  G       G+KG +G  G PGP              
Sbjct: 192  GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMG 251

Query: 1155 -----------PGPIGLQGLPGPP-----GEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198
                       PGP G  G+ GPP     G  GE G+ G  G PG PGPRGP G  G  G
Sbjct: 252  FPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQG 311

Query: 1199 PQGPPGSVGSVG--------GV-GEKGE---PGE-----------AGNPGPPGEAGVGGP 1235
            P G  G  G++G        G+ G+KG+   PG            +GNPG PG  G+ G 
Sbjct: 312  PPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGL 371

Query: 1236 KGERGEKGEAGP------PGAAGPPGAKGP---PGDDGPKGNPGPV-----------GFP 1275
            KG+ G +G  GP      P  +G PGA GP   PG  G +GNPG             G P
Sbjct: 372  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 431

Query: 1276 GDPGPPGEPGP-----------AGQDGVGGDKGEDGDPGQPGPPGPSG---------EAG 1315
            G PGPPG P P           +G  G+ G++G  G+ G  G  G SG           G
Sbjct: 432  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 491

Query: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQGPAGKPGP----- 1367
            PPG PG  GP G  G  G +G +G +G  GA+GP   PG  GP+GP GP GK G      
Sbjct: 492  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 551

Query: 1368 -EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-----------PGSKGEKGH 1415
             +G+ G  G  G QG  G  G+ G  G  G PGLPGL GD           PG  GEKGH
Sbjct: 552  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 611

Query: 1416 P--------GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG---DGGIPGPAGPLGPPGPP 1464
            P        GL GL GP G  G+KG  GLPG QG PG+KG      IPG  GP G PG P
Sbjct: 612  PGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTP 671

Query: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGP---------PGSPGPPGE 1502
            G PGP+G +G  G+ G  G  G  G PG          PG PGP GE
Sbjct: 672  GFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGE 718



 Score =  374 bits (959), Expect = e-103
 Identities = 238/548 (43%), Positives = 277/548 (50%), Gaps = 78/548 (14%)

Query: 1046 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP---AGSPGEDGDKGEIGEPGQKGSKG 1102
            P G +   G        G  G  GP+G+ GP GP    GS G  G KGE G PG  G  G
Sbjct: 29   PCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG 88

Query: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1162
             KG+ GP G PG    +G  GI G  G+PGPRG  G+ G  G +GA GFPGP G  GL G
Sbjct: 89   PKGDKGPMGVPGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLG 145

Query: 1163 LPGPPGEKGENGDVGPMGPPGP-PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1221
             PG PG+KG  GD  P+  PG   G +G  G  G DG  GP G+ G  G VG  G PG  
Sbjct: 146  PPGLPGQKGSKGD--PVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQ 203

Query: 1222 GNPGPPGEAGVGGP-----KGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNP 1269
            G PGPPG  G  G      +GE+G KG+ G PG AGPP + G       P G  G KG P
Sbjct: 204  GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 263

Query: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329
            GP GFPG  GPPG PG  G  G  G+KGE G PG PGP GP G  G  GPPG++G  G  
Sbjct: 264  GPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTL 322

Query: 1330 GAEGRQGEKGAKGEAGAEGPPGK-----------TGPVGPQGPAGKPGPEGLRGIPGPVG 1378
            G  G  G +G +G+ G  G PG            +G  G  G  G PG +G  GI G  G
Sbjct: 323  GFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRG 382

Query: 1379 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE-----KGHPGLIGLIGPP-------- 1425
              G+PG     G PG +GP G PGLKGD G+ G       G PG  GL GPP        
Sbjct: 383  PSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSP 442

Query: 1426 ------------------GEQGEKGDRGLPGTQGSPG-AKGDGGIP--GPAGPLGPPGP- 1463
                              GEQG KG+ GL G +G  G    DGG+P  GP G  GPPGP 
Sbjct: 443  EFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPW 502

Query: 1464 --PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521
               GLPG +G +G++GS G  G  G  GL GP G  GP G+  +  PILS+       +G
Sbjct: 503  GLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK--KGEPILST------IQG 554

Query: 1522 MQADADDN 1529
            M  D  D+
Sbjct: 555  MPGDRGDS 562



 Score =  103 bits (258), Expect = 1e-21
 Identities = 73/183 (39%), Positives = 83/183 (45%), Gaps = 27/183 (14%)

Query: 1343 EAGAEGPPGKTGPVGPQGPAGKPG--PE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG 1399
            E  A G      P G Q  +G     PE G RG PGP+G QG            P GP G
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQG------------PTGPQG 64

Query: 1400 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1459
              G  G  G KGE+G PGL+G  GP G++G           G PG  G  GIPG  G  G
Sbjct: 65   FTGSTGLSGLKGERGFPGLLGPYGPKGDKGP---------MGVPGFLGINGIPGHPGQPG 115

Query: 1460 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1519
            P GPPGL G  G +G  G  GP G  G   L GPPG PG  G    P+    S K  +  
Sbjct: 116  PRGPPGLDGCNGTQGAVGFPGPDGYPG---LLGPPGLPGQKGSKGDPVLAPGSFKGMKGD 172

Query: 1520 EGM 1522
             G+
Sbjct: 173  PGL 175


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  825 bits (2130), Expect = 0.0
 Identities = 537/1283 (41%), Positives = 614/1283 (47%), Gaps = 241/1283 (18%)

Query: 422  PTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAIL 481
            P+GP G  G+RG            LPGPPG+        G  G++G           A L
Sbjct: 332  PSGPKGGKGERG------------LPGPPGSK-------GEKGARGN--DCVRISPDAPL 370

Query: 482  QQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-- 539
            Q A     GP G  G +G  GP G PGS+G KG+ G+ G  G +GV G PG  G+PG+  
Sbjct: 371  QCAE----GPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEIC 426

Query: 540  -------RGRPGADGGRGMPGEPGAKGDRGFDG--LPGLPGDKGHRGERGPQGPPGPPGD 590
                   +G PG  G  G+ GEPG  G  G  G  LPG PGD G        GPPGP GD
Sbjct: 427  VIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG--------GPPGPKGD 478

Query: 591  DGMRGEDGEIGPRGLPGEAGPRGLLGP--RGTPGAP-GQPGMAGVDGPPGPKGNMG-PQG 646
             G  G  G+ GP G PG+ G +G  G      P  P G     G+ G PGPKG  G P  
Sbjct: 479  KGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVP 538

Query: 647  EPGPPGQQGNPGPQGLP--------GPQGPIGPPGEKGPQGKPG--LAGLPGADGPPGHP 696
              G PG QG  G +G P        G Q  +   G  G  G PG  L GLPG  G PG  
Sbjct: 539  ARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLK 598

Query: 697  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA------------DG---VRGLKGSKGEK 741
            G++G  GE G  G PGP GP+G  G +G KG             DG   V  L G  GEK
Sbjct: 599  GEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEK 658

Query: 742  GEDGFPGF--------KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 793
            GE G PGF         G+ GLKG +G+ G  G  G  G  G  G +G  G  GP+G  G
Sbjct: 659  GEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKG 718

Query: 794  EKGK---------------LGVPGLPGYPGRQGPKG-----STGFPGFPGANGEKGARGV 833
            EKG                 G PG PG  G QGP+G       G PG PG  G  G +GV
Sbjct: 719  EKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGV 778

Query: 834  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893
             G+PGP G RG  GP+G  GA    G PG +G  G  GPPGP GE+G QG  G  G  GP
Sbjct: 779  QGEPGPPG-RGVQGPQGEPGA---PGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGP 834

Query: 894  KGPPG-----PPGKDG---------LPGHPGQRGETGFQGKTGPPGPGGVV--GPQGPTG 937
             GPPG     PPG+DG          PG  G RGE G  G+   P  G ++  G  G  G
Sbjct: 835  VGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPG 894

Query: 938  -------ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK---------- 980
                   + GP G  G PGPPGPPG  GL G  G  G  G PG     G           
Sbjct: 895  LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKS 954

Query: 981  ---DGPAGLRGFPG---ERGLPGAQGAPGLKGGE-------------------------- 1008
               D   G R  PG   E+G  G QG PG+ G +                          
Sbjct: 955  ICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDP 1014

Query: 1009 ---GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1065
               G  G PGP G PG+RG  G  G  G PG PGP GPPG  G  G+PG  G QG  G  
Sbjct: 1015 GCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLT 1074

Query: 1066 GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1125
            G+ G  G PGP G  G PG  G  G  G  G++G  G  GE G PGPPG +G  G PG A
Sbjct: 1075 GLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPA 1134

Query: 1126 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL---PGPPGEKGENGDVGPMGP- 1181
            G  GE GP+G  G  G +G +G  GFPGPPGP G  G    PGPPG + E G  G  GP 
Sbjct: 1135 GPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS 1194

Query: 1182 -----PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1236
                 PGPPGP G QGP G DG  G  G  G  G  G  G PG  G PG  G+ G  G  
Sbjct: 1195 GLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLP 1254

Query: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG--G 1294
            G +G+ G+ GPPG+ G PGA+G PG  GP+G PGP G  G PGPPG+PGPAG   VG  G
Sbjct: 1255 GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKG 1314

Query: 1295 DKGEDGD------PGQPGPPG---PSGE------AGPPGPPGKRG------PPGAAGAEG 1333
            D+G  G+      PGQPGPPG   P GE      AG  GPPGK+G      P G  GA G
Sbjct: 1315 DRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAG 1374

Query: 1334 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-- 1391
            ++G+ G KG AG  G PGK+G +GP GP G  G  G  G PGP G  GLPG  G  G   
Sbjct: 1375 QKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMV 1434

Query: 1392 ----------------------------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1423
                                          PM     PG  G PG  G  G PG  G  G
Sbjct: 1435 NYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPG 1494

Query: 1424 PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG--NKGSTGP 1481
             PG+ G +G +GLPG +G PG KG+ G  G  G  G  G PG PGPQGP G    G+TGP
Sbjct: 1495 LPGQIGREGRQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPGYGKMGATGP 1553

Query: 1482 AGQKGDSGLPGPPG---SPGPPG 1501
             GQ+G  G+PGPPG    PG  G
Sbjct: 1554 MGQQGIPGIPGPPGPMGQPGKAG 1576



 Score =  804 bits (2077), Expect = 0.0
 Identities = 565/1567 (36%), Positives = 693/1567 (44%), Gaps = 316/1567 (20%)

Query: 80   AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNEHGIQQIGVEVGRSPV 136
            A ++ PT+++FP G  PE+F+++ T+  KK       +L  + + +G  QI +EV     
Sbjct: 82   APVTQPTRRVFPRG-LPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQER 140

Query: 137  FLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERA 196
             L     G+       +F    + D +WH++ +SV  +  ++ VDC   +++PL    R 
Sbjct: 141  SLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPL--GPRR 198

Query: 197  IVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDY--CEHYSPDCDSSAPKAAQ-A 253
             +   G    G      +    D+QQ  I  DP+   +   CE     C     KA +  
Sbjct: 199  PMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDT 258

Query: 254  QEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQR 313
            Q  ++ E N   + + Y       +  E P++               +  LTG    SQ+
Sbjct: 259  QSNELIEINPQSEGKVYT----RCFCLEEPQNSE------------VDAQLTGRI--SQK 300

Query: 314  KNSEDTLYENKEID--------GRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPG 365
                  +++    D         RDS++ +                  P+ P   +   G
Sbjct: 301  AERGAKVHQETAADECPPCVHGARDSNVTL-----------------APSGPKGGKGERG 343

Query: 366  VPAETDITETSINGHGAYGEKGQKGEPAVV----EPGMLVEGPPGPAGPAGIMGPPGLQG 421
            +P             G+ GEKG +G   V      P    EGP G  G +G +GP GL G
Sbjct: 344  LPGPP----------GSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPG 393

Query: 422  PTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML-PFRYGGD-GSKGPTISAQEAQAQA 479
             TG  G  G++G  G  G+PG  G  G PG + ++ P    GD G  GP   A E     
Sbjct: 394  STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG 453

Query: 480  ILQQARIAL-------RGPPGP------MGLTGRPGPVGGPGSSGAKGESGDP------- 519
            +     I L        GPPGP       G+ G+ GP G PG  G KGE GDP       
Sbjct: 454  LPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTL 513

Query: 520  --GPQGPRGVQGPPGPTGKPG----KRGRPGADGGRGMPGEP-----------------G 556
              G Q   G+ G PGP G+PG     RG PG  G +G  GEP                 G
Sbjct: 514  PEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTG 573

Query: 557  AKGDRGFD-----------GLPGLPGDKGHRGERGPQGPPGPPGDDGMRG---------- 595
            A GD G             G+PGL G+KG+ GE GP G PGPPG  G  G          
Sbjct: 574  ASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCE 633

Query: 596  --------EDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 647
                    +DG++    LPG +G +G  GP G  G PG+ G AG  G  G KG+ G  G+
Sbjct: 634  PCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGD 692

Query: 648  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGP---------------QGKPGLAGLPGADGP 692
            PG PG  G PG  G PG QGP GP GEKG                 G+PG  G  G  GP
Sbjct: 693  PGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGP 752

Query: 693  P--GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750
               G PGK GQ G  G  GPPG +G  G PGP G          +G +G +GE G PG  
Sbjct: 753  EGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG----------RGVQGPQGEPGAPGLP 802

Query: 751  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP--SGQAGEKGKLGVPGLPGYPG 808
            G  GL G RG  G  G +G  G  G KG  GP G PG   SG  G  G+ G  GL G PG
Sbjct: 803  GIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPG 862

Query: 809  RQGPKGSTGFPGFPG--ANGEKGARGVAGKP----GPRGQRGPTGPRGSRGARGPTGKPG 862
             +GP+G  G PG     + G+    G+ G P    G   Q GP GP G  G  GP G PG
Sbjct: 863  EKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPG 922

Query: 863  PKGTSGGDGPPGPPG----------------------------------ERGPQGPQGPV 888
             +G  G +G PG PG                                  E+G +G QG  
Sbjct: 923  LQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIP 982

Query: 889  GFPG-----------------------PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925
            G PG                        +G PG  G  GLPG PG  G+   +G+ GPPG
Sbjct: 983  GVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQ---RGEEGPPG 1039

Query: 926  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985
              G  GP GP G  G  G  G PG PG  GE+GL G  G +G  G PG  G  G  GP G
Sbjct: 1040 MRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPG 1099

Query: 986  LRGFPGERGLPGA---QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP------IGLPG 1036
            L G  GERG  G+   +G PG  G EG  GPPGP G  GERG  G +G        G PG
Sbjct: 1100 LPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPG 1159

Query: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1096
             PGP GPPG  G+ G+PG  GPQ   G +G++GP GLPG  GP G PG  G  G  G  G
Sbjct: 1160 FPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDG 1219

Query: 1097 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156
            + G  G +G+ GP GPPGL GP G  G  G  G PGP+G  G  G  G  G  G  G PG
Sbjct: 1220 KDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPG 1279

Query: 1157 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGP-----------RGPQGPNGADGPQGPPGS 1205
             +G QG PGPPG       VGP GPPG PGP           RG  G  G  G  G PG 
Sbjct: 1280 AMGPQGRPGPPGH------VGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGP 1333

Query: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265
             G  G  GE G  G AG  GPPG+ G  GP G +G+ G AG  G AG  G  G PG  G 
Sbjct: 1334 PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGK 1393

Query: 1266 KGNPGPVGFP---GDPGPPGEPGPAGQDGVGGDKGEDGD--------------------- 1301
             G+ GPVG P   G+ G PG PGP+G  G+ G  G  GD                     
Sbjct: 1394 SGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDE 1453

Query: 1302 ------------------PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
                              PG+PGPPG  G  G PG PG  G PG  G EGRQG  G +G 
Sbjct: 1454 RMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGL 1513

Query: 1344 AGAEGP--------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395
             G +G          G+ G  GP GP G PG  G  G  GP+G+QG+PG     GPPGPM
Sbjct: 1514 PGTKGEKGDIGIGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPGI---PGPPGPM 1569

Query: 1396 GPPGLPG 1402
            G PG  G
Sbjct: 1570 GQPGKAG 1576



 Score =  791 bits (2042), Expect = 0.0
 Identities = 518/1298 (39%), Positives = 595/1298 (45%), Gaps = 308/1298 (23%)

Query: 497  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPG 556
            LTGR   +      GAK        + P  V G           G  G  G RG+PG PG
Sbjct: 293  LTGR---ISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPG 349

Query: 557  AKGDRGF--------------------------------DGLPGLPGDKGHRGERGP--- 581
            +KG++G                                  GLPG  G+KG +GE+G    
Sbjct: 350  SKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGI 409

Query: 582  QGPPGPPGDD------------GMRGEDGEIGPRGLPGEAGPRGLLGPR--GTPGAPGQP 627
            +G PG PG D            G +G+ G +GP GL GE GP GL GP   G PG PG P
Sbjct: 410  KGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDP 469

Query: 628  GMAGVDGPPGPKGNM---------GPQGEPGPPGQQGNPGPQ---------------GLP 663
            G     GPPGPKG+          GP G+PG PG +G  G                 GLP
Sbjct: 470  G-----GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLP 524

Query: 664  GPQGPIGPPGE-------------KGPQGKP----------------------------G 682
            G  GP G PG+             KG +G+P                            G
Sbjct: 525  GKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFG 584

Query: 683  LAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG------------ 730
            L GLPG  G PG  G++G  GE G  G PGP GP+   GP G+KGA G            
Sbjct: 585  LPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPV---GPAGIKGAKGEPCEPCPALSNL 641

Query: 731  ------VRGLKGSKGEKGEDGFPGF--------KGDMGLKGDRGEVGQIGPRGEDGPEGP 776
                  V  L G  GEKGE G PGF         G+ GLKG +G+ G  G  G  G  G 
Sbjct: 642  QDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701

Query: 777  KGRAGPTGDPGPSGQAGEKG---------------KLGVPGLPGYPGRQGPK-----GST 816
             G +G  G  GP+G  GEKG                 G PG PG  G QGP+     G  
Sbjct: 702  PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKP 761

Query: 817  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP 876
            G PG PG  G  G +GV G+PGP G RG  GP+G  GA    G PG +G  G  GPPGP 
Sbjct: 762  GQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGA---PGLPGIQGLPGPRGPPGPT 817

Query: 877  GERGPQGPQGPVGFPGPKGPP-----GPPGKD---------GLPGHPGQRGETGFQGKTG 922
            GE+G QG  G  G  GP GPP     GPPG+D         G PG  G RGE G  G+  
Sbjct: 818  GEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECS 877

Query: 923  PPGPGGVV--GPQGPTG-------ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPG 973
             P  G ++  G  G  G       + GP G  G PGPPGPPG  GL G  G  G  G PG
Sbjct: 878  CPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPG 937

Query: 974  PQGISGK-------------DGPAGLRGFPG---ERGLPGAQGAPGLKGGE--------- 1008
                 G              D   G R  PG   E+G  G QG PG+ G +         
Sbjct: 938  LTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSL 997

Query: 1009 --------------------GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048
                                G  G PGP G PG+RG  G  G  G PG PGP GPPG  G
Sbjct: 998  ERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPG 1057

Query: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108
              G+PG  G QG  G  G+ G  G PGP G  G PG  G  G  G  G++G  G  GE G
Sbjct: 1058 AVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKG 1117

Query: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ---GLPG 1165
             PGPPG +G  G PG AG  GE GP+G  G  G +G +G  GFPGPPGP G     G PG
Sbjct: 1118 EPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPG 1177

Query: 1166 PPGEKGENGDVGPMGP------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219
            PPG + E G  G  GP      PGPPGP G QGP G DG  G  G  G  G  G  G PG
Sbjct: 1178 PPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPG 1237

Query: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279
              G PG  G+ G  G  G +G+ G+ GPPG+ G PGA+G PG  GP+G PGP G  G PG
Sbjct: 1238 LMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPG 1297

Query: 1280 PPGEPGPAGQDGVG--GDKGEDGD------PGQPGP---PGPSGE------AGPPGPPGK 1322
            PPG+PGPAG   VG  GD+G  G+      PGQPGP   PGP GE      AG  GPPGK
Sbjct: 1298 PPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGK 1357

Query: 1323 R------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376
            +      GP G  GA G++G+ G KG AG  G PGK+G +GP GP G  G  G  G PGP
Sbjct: 1358 QGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGP 1417

Query: 1377 VGEQGLPGAAGQDGP------------------------------PGPMGPPGLPGLKGD 1406
             G  GLPG  G  G                                 PM     PG  G 
Sbjct: 1418 SGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGP 1477

Query: 1407 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466
            PG  G  G PG  G  G PG+ G +G +GLPG +G PG KG+ G  G  G  G  G PG 
Sbjct: 1478 PGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGP 1536

Query: 1467 PGPQGPK--GNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502
            PGPQGP   G  G+TGP GQ+G  G+PGPPG  G PG+
Sbjct: 1537 PGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGK 1574



 Score =  761 bits (1966), Expect = 0.0
 Identities = 496/1240 (40%), Positives = 575/1240 (46%), Gaps = 246/1240 (19%)

Query: 472  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531
            +Q+A+  A + Q   A   PP   G       +   G  G KGE G PGP G +G +G  
Sbjct: 298  SQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGAR 357

Query: 532  GPTGKPGKRGRP--GADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589
            G          P   A+G +G  GE GA G  G  G  G  G KG +G+ G +G PG PG
Sbjct: 358  GNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPG 417

Query: 590  DDG------------MRGEDGEIGPRGLPGEAGPRGLLGPRGT--PGAPGQPGMAGVDGP 635
             DG             +G+ G +GP GL GE GP GL GP G   PG PG PG     GP
Sbjct: 418  RDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG-----GP 472

Query: 636  PGPKGNMG---------PQGEPGPPGQQGNPGPQ---------------GLPGPQGPIGP 671
            PGPKG+ G         P G+PG PG +G  G                 GLPG  GP G 
Sbjct: 473  PGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGE 532

Query: 672  PGE-------------KGPQGKP----------------------------GLAGLPGAD 690
            PG+             KG +G+P                            GL GLPG  
Sbjct: 533  PGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRA 592

Query: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA------------DG---VRGLK 735
            G PG  G++G  GE G  G PGP GP+G  G +G KG             DG   V  L 
Sbjct: 593  GVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALP 652

Query: 736  GSKGEKGEDGFPGF--------KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 787
            G  GEKGE G PGF         G+ GLKG +G+ G  G  G  G  G  G +G  G  G
Sbjct: 653  GPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQG 712

Query: 788  PSGQAGEKGK---------------LGVPGLPGYPGRQGPKG-----STGFPGFPGANGE 827
            P+G  GEKG                 G PG PG  G QGP+G       G PG PG  G 
Sbjct: 713  PAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGP 772

Query: 828  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887
             G +GV G+PGP G RG  GP+G  GA    G PG +G  G  GPPGP GE+G QG  G 
Sbjct: 773  PGLKGVQGEPGPPG-RGVQGPQGEPGA---PGLPGIQGLPGPRGPPGPTGEKGAQGSPGV 828

Query: 888  VGFPGPKGPPG-----PPGKDG---------LPGHPGQRGETGFQGKTGPPGPGGVV--G 931
             G  GP GPPG     PPG+DG          PG  G RGE G  G+   P  G ++  G
Sbjct: 829  KGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSG 888

Query: 932  PQGPTG-------ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK---- 980
              G  G       + GP G  G PGPPGPPG  GL G  G  G  G PG     G     
Sbjct: 889  MPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIE 948

Query: 981  ---------DGPAGLRGFPG---ERGLPGAQGAPGLKGGEG------PQGPPGPVGSPGE 1022
                     D   G R  PG   E+G  G QG PG+ G +           P    + G+
Sbjct: 949  QHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGD 1008

Query: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082
              S G  G +G PG PGP G PG  GE+G PG +G  GP G      P+G PG  G  GS
Sbjct: 1009 N-SEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPG------PIGPPGFPGAVGS 1061

Query: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1142
            PG  G +GE    G  G  GDKGE GPPG PG  G  G PG+ G  GE G  G  G  G+
Sbjct: 1062 PGLPGLQGE---RGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE 1118

Query: 1143 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202
             G  G+ G PGPPGP G +G  GP G  GE GD G  G PG PGP GP G  G  G  GP
Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGP 1178

Query: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262
            PG     G  G +G  G  G+PGPPG  G+ GP G  G  G+ G PG  G PG  GPPG 
Sbjct: 1179 PGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGL 1238

Query: 1263 DGPKGNPGPVGFPGDPGPPGE---PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGP 1319
             GP G  G  G PG PGP G+   PGP G  G  G +GE G  G  G PGP G  GPPGP
Sbjct: 1239 MGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298

Query: 1320 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1379
            PG+ GP G + A G +G++GA GE G  G PG+ GP G  GP G+PG +           
Sbjct: 1299 PGQPGPAGIS-AVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTD----------- 1346

Query: 1380 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1439
                GAAG++GPPG  G  G PG KGDPG+ G+KG  G  G  G PG  G+ G  G    
Sbjct: 1347 ----GAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMG---P 1399

Query: 1440 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN------------------------ 1475
             G PG  G+ G PG  GP G PG PG+PG  G   N                        
Sbjct: 1400 VGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYT 1459

Query: 1476 ------------KGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503
                         G  GP G+ G  G PG PGSPG PG++
Sbjct: 1460 SRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQI 1499



 Score =  684 bits (1766), Expect = 0.0
 Identities = 449/1112 (40%), Positives = 523/1112 (47%), Gaps = 170/1112 (15%)

Query: 347  YKEYEDKPTSP-PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEP-----AVVEPGML 400
            ++ +   P  P P  E G  VPA  D         G  G KG+KGEP     +VV    L
Sbjct: 517  FQNFVGLPGKPGPKGEPGDPVPARGD--------PGIQGIKGEKGEPCLSCSSVVGAQHL 568

Query: 401  VE--GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 458
            V   G  G  G  G  G PGL G  G PG  G++G  G  G  G+ G PGP G       
Sbjct: 569  VSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPA----- 622

Query: 459  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD 518
              G  G+KG     +   A + LQ   + +   PGP G  G PGP G  G  G +G++G+
Sbjct: 623  --GIKGAKGEP--CEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGE 677

Query: 519  PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDG------------- 565
             G +G +G  G PG  G PG  GRPG  G  G+ G  G KG++G DG             
Sbjct: 678  RGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTD 736

Query: 566  LPGLPGDKGHRGERGPQGP--PGPPGDDGMRGEDGEIGPRGLPGEAGP--RGLLGPRGTP 621
            + G PG  G +GE+GP+G   PG PG  G+ G  G  G +G+ GE GP  RG+ GP+G P
Sbjct: 737  MAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEP 796

Query: 622  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681
            GAPG PG+ G+ GP GP G  G +G  G PG +G  GP G PG     GPPG  G QG+ 
Sbjct: 797  GAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVS-GPPGRDGQQGQT 855

Query: 682  GLAGLPGADGPPGHPGKEGQ-----------SGEKGALG-------PPGPQGPIGYPGPR 723
            GL G PG  GP G  G+ G+           SG  GA G        PGPQGP G PGP 
Sbjct: 856  GLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPP 915

Query: 724  GVKGADGVRGLKGSKGEKGEDGF----------------------------PGFKGDMGL 755
            G  G  G++G+ G+ G  G+ G                             PG+  + G 
Sbjct: 916  GPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGE 975

Query: 756  KGDRGEVGQIG-------------PRGE----DGPEGPKGRAGPTGDPGPSGQAGEKGKL 798
            KGD+G  G  G             PR E    D  EG  G  G  G PGP G  G++G+ 
Sbjct: 976  KGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEE 1035

Query: 799  GVPGLPGYPGRQGPKGSTGFPGF---PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 855
            G PG+ G PG  GP G  GFPG    PG  G +G RG+ G  G +G+ GP G  G  GA 
Sbjct: 1036 GPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 856  GPTGKPGPKG------TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK------D 903
            GP G PG KG      ++G  G PGPPG  G  GP GP G  G +GP G  G+       
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963
            G PG PG  G  GF GK G PGP G    +G  G  GP G  G PGPPGPPG QG  G  
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023
            G +G  G PG +G  G  GP GL G PG +G  G  G PG KG  G  GPPG  G PG  
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKG-----APGEKGPQGPAGRDGVQGPVGLPGPAG 1078
            G  G  GP G PG PG  GPPGP G+ G     A G KG +G  G  G+ G  G PGP G
Sbjct: 1276 GEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335

Query: 1079 ---PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1135
               P G PG DG  G+ G PG++G  G  G  G PG  G +G  G  G AG  G PG  G
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395

Query: 1136 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG------------------ 1177
              G  G  G  G RG PG PGP G  GLPG PG  G+  +                    
Sbjct: 1396 SMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERM 1455

Query: 1178 ---------PM---GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1225
                     PM     PG PGP G  G  G  G  G PG  G +G  G +G PG  G PG
Sbjct: 1456 AYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPG 1515

Query: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPG-----AKGPPGDDGPKGNPGPVGFPGDPGP 1280
              GE G  G  G  GE G  GPPG  GPPG     A GP G  G  G PGP G  G PG 
Sbjct: 1516 TKGEKGDIGI-GIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGK 1574

Query: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312
             G   P+  D  G    E   P      GP G
Sbjct: 1575 AGHCNPS--DCFGAMPMEQQYPPMKTMKGPFG 1604



 Score =  678 bits (1750), Expect = 0.0
 Identities = 454/1146 (39%), Positives = 517/1146 (45%), Gaps = 250/1146 (21%)

Query: 602  PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 661
            P+    +A   G +  +   GA      A  + PP   G         P G +G  G +G
Sbjct: 284  PQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERG 343

Query: 662  LPGPQG-------------------PI----GPPGEKGPQGKPGLAGLPGADGPPGHPGK 698
            LPGP G                   P+    GP GEKG  G  G +GLPG+ G  G  G+
Sbjct: 344  LPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGE 403

Query: 699  EGQSGEKGALGPPGPQGPIG---YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755
            +G  G KG  G PG  G  G     GP+G KG  G  G +G  GE G  G PG  G +GL
Sbjct: 404  KGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPG-IGL 462

Query: 756  KGDRGEV-GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG---------KLGVPGLPG 805
             G  G+  G  GP+G+ G  G  G+ GP G PG  G  GEKG           G     G
Sbjct: 463  PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVG 522

Query: 806  YPGRQGPKGSTGFP----GFPGANGEKGARG--------VAGKPGPRGQRGPTGPRGS-- 851
             PG+ GPKG  G P    G PG  G KG +G        V G        G +G  GS  
Sbjct: 523  LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG 582

Query: 852  ---RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG------------------- 889
                G  G  G PG KG  G  G  GP G  GP GP GP G                   
Sbjct: 583  FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQ 642

Query: 890  --------FPGP---KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 938
                     PGP   KG PGPPG  GLPG  G+ GE G +G+ G  G  G  G  G TG 
Sbjct: 643  DGDVRVVALPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701

Query: 939  TGPIGERGHPGPPGPPGEQG-----LPGAAG----KEGAKGDPGPQGISGKDGPAGLRGF 989
             G  GE G  GP GP GE+G      P   G      G  G PGP+G  G +G  G  G 
Sbjct: 702  PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG-VGRPGK 760

Query: 990  PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1049
            PG+ GLPG QG PGLKG +G  GPPG  G  G +G  G  G  G+ G PGP+GPPGP GE
Sbjct: 761  PGQPGLPGVQGPPGLKGVQGEPGPPGR-GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGE 819

Query: 1050 KGA---PGEKGPQGPAGRDG--VQGPVGLPGPAGPA---GSPGEDGDKGEIGEPGQ---- 1097
            KGA   PG KG  GP G  G  V GP G  G  G     G+PGE G +GE GEPG+    
Sbjct: 820  KGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP 879

Query: 1098 -----------------KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1140
                              GS    G  GPPG PG  GP G PG+ G  G  G  GQ G+ 
Sbjct: 880  SQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939

Query: 1141 ----------------------------------GQKGDEGARGFP-------------- 1152
                                              G+KGD+G  G P              
Sbjct: 940  AELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLER 999

Query: 1153 ------------GPPGPIGLQGLPGPPGEKGENGDVGP---MGPPGPPGPRGPQGPNGAD 1197
                        G PG +G  GLPGPPG  G+ G+ GP    G PGPPGP GP G  GA 
Sbjct: 1000 PRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAV 1059

Query: 1198 GPQGPPGSVGS---VGGVGEKGEPGEAGNPGPPGEA---GVGGPKGER------GEKGEA 1245
            G  G PG  G     G  G+KGEPG  G PG PG     G+ G KGER      GEKGE 
Sbjct: 1060 GSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP 1119

Query: 1246 GPPGA---AGPPGAKGPPGDDGPKGN---------PGPVGFPGDPGPPGEPGPAGQDGVG 1293
            GPPG+    GPPG  GP G+ GP+GN          G  GFPG PGPPG PG  G  G  
Sbjct: 1120 GPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179

Query: 1294 GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353
            G + E G  G  GP G  G  GPPGPPG +GP G  G +G+ G+ G +G+ G  GPPG  
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM 1239

Query: 1354 GP------------VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1401
            GP             GP+G  GKPGP G  G PG  GE G  G  G+ GPPG +GPPG P
Sbjct: 1240 GPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPP 1299

Query: 1402 -----------GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG 1450
                       GLKGD G+ GE+G  GL G  GPPG  G  G+ G  G  G  G  G  G
Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359

Query: 1451 IPGPAGPLGPPGP---------------PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG 1495
              GP GP G PG                PG PG  G  G  G  GPAG++G  G PGP G
Sbjct: 1360 FYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSG 1419

Query: 1496 SPGPPG 1501
            SPG PG
Sbjct: 1420 SPGLPG 1425



 Score =  265 bits (678), Expect = 2e-70
 Identities = 169/415 (40%), Positives = 200/415 (48%), Gaps = 65/415 (15%)

Query: 1153 GPPGPIGLQGLPGPPGEKGENG----DVGPMGPPGP----PGPRGPQGPNGADGPQGPPG 1204
            GP G  G +GLPGPPG KGE G    D   + P  P     GP+G +G +GA GP G PG
Sbjct: 334  GPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPG 393

Query: 1205 SVGSVGGVGEKGE------PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258
            S G  G  GEKG+      PG+ G  G PGE  V GPKG++G+ G  GP G AG PG  G
Sbjct: 394  STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG 453

Query: 1259 PPGDDG---------PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP------- 1302
             PG  G         P G PGP G  G  G PG+ GP G+ G  G KGE GDP       
Sbjct: 454  LPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTL 513

Query: 1303 --------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK--------GAKGEAGA 1346
                    G PG PGP GE G P P   RG PG  G +G +GE         GA+    +
Sbjct: 514  PEGFQNFVGLPGKPGPKGEPGDPVPA--RGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSS 571

Query: 1347 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1406
             G  G  G  G  G  G PG  G+ G+ G  G  G  G AG  GPPGP+GP G+ G KG+
Sbjct: 572  TGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGE 630

Query: 1407 PG------SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1460
            P       S  + G   ++ L GP GE+GE G  G  G  G  G  G+ G+ G  G  G 
Sbjct: 631  PCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGN 689

Query: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1515
            PG PG PG         +TG  G  G+ G+ GP G  G  G+     P L    T
Sbjct: 690  PGDPGTPG---------TTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVT 735



 Score =  225 bits (574), Expect = 3e-58
 Identities = 158/368 (42%), Positives = 179/368 (48%), Gaps = 43/368 (11%)

Query: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1249
            P GP G  G +G PG  GS G  G +G      +P  P +   G PKGE+GE G  GP G
Sbjct: 332  PSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG-PKGEKGESGALGPSG 390

Query: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309
                PG+ G  G  G KG+ G  G PG PG  G PG   +  V G KG+ GDPG  GP G
Sbjct: 391  L---PGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPG---EICVIGPKGQKGDPGFVGPEG 444

Query: 1310 PSGEAGPPGPPGKRGP--PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1367
             +GE GPPG PG  G   PG  G  G  G  G KG+ G+ G PGK GP    G  GKPG 
Sbjct: 445  LAGEPGPPGLPGPPGIGLPGTPGDPG--GPPGPKGDKGSSGIPGKEGP---GGKPGKPGV 499

Query: 1368 EGLRGIPG---PVGEQGLPGAAGQDGPPGPMGPPGLP-GLKGDPGS---KGEKGHP---- 1416
            +G +G P    P   +G     G  G PGP G PG P   +GDPG    KGEKG P    
Sbjct: 500  KGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSC 559

Query: 1417 ----GLIGLIGPPGEQGEKGDRG-----LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1467
                G   L+   G  G+ G  G     LPG  G PG KG+ G  G AGP G PGPPG  
Sbjct: 560  SSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPV 619

Query: 1468 GPQGPKGNKGSTG---PAG---QKGDS---GLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1518
            GP G KG KG      PA    Q GD     LPGP G  G PG     LP    K   R 
Sbjct: 620  GPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERG 679

Query: 1519 TEGMQADA 1526
             +G + DA
Sbjct: 680  LKGQKGDA 687



 Score =  211 bits (536), Expect = 7e-54
 Identities = 146/360 (40%), Positives = 167/360 (46%), Gaps = 49/360 (13%)

Query: 1199 PQGPPGSVGSVGGVGEKGEPGE------AGNPGPPGEAGV---------GGPKGERGEKG 1243
            PQ         G + +K E G       A +  PP   G           GPKG +GE+G
Sbjct: 284  PQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERG 343

Query: 1244 EAGPPGAAGPPGAKG-------PPGD----DGPKGNPGPVGFPGDPGPPGEPGPAGQDGV 1292
              GPPG+ G  GA+G       P       +GPKG  G  G  G  G PG  G  GQ G 
Sbjct: 344  LPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGE 403

Query: 1293 GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP--P 1350
             GD G  G PG+PG  G  GE    GP G++G PG  G EG  GE G  G  G  G   P
Sbjct: 404  KGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLP 463

Query: 1351 GKTG-PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG------PMGPPGLPGL 1403
            G  G P GP GP G  G  G+ G  GP G+ G PG  G+ G P       P G     GL
Sbjct: 464  GTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGL 523

Query: 1404 KGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--------GTQ---GSPGAKGDGGIP 1452
             G PG KGE G P  +   G PG QG KG++G P        G Q    S GA GD G P
Sbjct: 524  PGKPGPKGEPGDP--VPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSP 581

Query: 1453 GPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSS 1512
            G   P G PG  G+PG +G KGN G  GPAG  G  G  GP G  G  GE  +P P LS+
Sbjct: 582  GFGLP-GLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSN 640


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.142    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 129,766,304
Number of Sequences: 37866
Number of extensions: 11801587
Number of successful extensions: 382039
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 709
Number of HSP's successfully gapped in prelim test: 1998
Number of HSP's that attempted gapping in prelim test: 33791
Number of HSP's gapped (non-prelim): 58908
length of query: 1767
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1651
effective length of database: 13,855,062
effective search space: 22874707362
effective search space used: 22874707362
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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