Guide to the Human Genome
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Search of human proteins with 98985806

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98985806 alpha 1 type XI collagen isoform A preproprotein
[Homo sapiens]
         (1806 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...  3879   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...  3786   0.0  
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...  3782   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]     2921   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...  2474   0.0  
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...  2246   0.0  
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...  2243   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]  2115   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...  1229   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...  1226   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]     1199   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]    1193   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                   1117   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]    1102   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   991   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   986   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   984   0.0  
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              947   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         936   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    920   0.0  
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              913   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        906   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   902   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   902   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   902   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   902   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               871   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   830   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   830   0.0  
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       825   0.0  

>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 3879 bits (10060), Expect = 0.0
 Identities = 1806/1806 (100%), Positives = 1806/1806 (100%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEA 300
            PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEA
Sbjct: 241  PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEA 300

Query: 301  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 360
            NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY
Sbjct: 301  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 360

Query: 361  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 420
            ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG
Sbjct: 361  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 420

Query: 421  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 480
            AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP
Sbjct: 421  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 480

Query: 481  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 540
            GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP
Sbjct: 481  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 540

Query: 541  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 600
            GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR
Sbjct: 541  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 600

Query: 601  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 660
            GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP
Sbjct: 601  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 660

Query: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720
            GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP
Sbjct: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720

Query: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780
            GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK
Sbjct: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 781  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840
            GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP
Sbjct: 781  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840

Query: 841  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900
            GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP
Sbjct: 841  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900

Query: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960
            GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT
Sbjct: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960

Query: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020
            GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD
Sbjct: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080
            GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ
Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080

Query: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140
            GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK
Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140

Query: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200
            GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200

Query: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260
            GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA
Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260

Query: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320
            GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP
Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320

Query: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380
            GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380

Query: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440
            GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP
Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440

Query: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500
            GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP
Sbjct: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500

Query: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560
            GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG
Sbjct: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560

Query: 1561 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1620
            MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG
Sbjct: 1561 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1620

Query: 1621 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1680
            EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL
Sbjct: 1621 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1680

Query: 1681 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1740
            LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE
Sbjct: 1681 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1740

Query: 1741 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1800
            EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG
Sbjct: 1741 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1800

Query: 1801 PVCFLG 1806
            PVCFLG
Sbjct: 1801 PVCFLG 1806


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 3786 bits (9819), Expect = 0.0
 Identities = 1770/1820 (97%), Positives = 1781/1820 (97%), Gaps = 16/1820 (0%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQ--- 297
            PDCDSSAPKAAQAQEPQIDE    +  +          ++++  T  P  +E+  ++   
Sbjct: 241  PDCDSSAPKAAQAQEPQIDEKKKSNFKKKMRTVATKSKEKSKKFT--PPKSEKFSSKKKK 298

Query: 298  -----------TEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGE 346
                        +ANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGE
Sbjct: 299  SYQASAKAKLGVKANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGE 358

Query: 347  DYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP 406
            DYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP
Sbjct: 359  DYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP 418

Query: 407  AETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPG 466
            AETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPG
Sbjct: 419  AETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPG 478

Query: 467  DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA 526
            DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA
Sbjct: 479  DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA 538

Query: 527  LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 586
            LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG
Sbjct: 539  LRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG 598

Query: 587  GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 646
            GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG
Sbjct: 599  GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPG 658

Query: 647  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706
            EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG
Sbjct: 659  EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718

Query: 707  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766
            PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG
Sbjct: 719  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 778

Query: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826
            ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG
Sbjct: 779  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838

Query: 827  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 886
            PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG
Sbjct: 839  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTG 898

Query: 887  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 946
            PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG
Sbjct: 899  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 958

Query: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1006
            HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG
Sbjct: 959  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1018

Query: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066
            AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG
Sbjct: 1019 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1078

Query: 1067 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126
            TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG
Sbjct: 1079 TAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138

Query: 1127 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1186
            DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG
Sbjct: 1139 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1198

Query: 1187 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG 1246
            ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG
Sbjct: 1199 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG 1258

Query: 1247 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1306
            SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG
Sbjct: 1259 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1318

Query: 1307 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366
            NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG
Sbjct: 1319 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1378

Query: 1367 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1426
            AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG
Sbjct: 1379 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1438

Query: 1427 QDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1486
            QDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG
Sbjct: 1439 QDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1498

Query: 1487 DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1546
            DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL
Sbjct: 1499 DGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1558

Query: 1547 PILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPART 1606
            PILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPART
Sbjct: 1559 PILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPART 1618

Query: 1607 CKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKE 1666
            CKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKE
Sbjct: 1619 CKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKE 1678

Query: 1667 KPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSG 1726
            KPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSG
Sbjct: 1679 KPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSG 1738

Query: 1727 SYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMIN 1786
            SYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMIN
Sbjct: 1739 SYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMIN 1798

Query: 1787 DFGDQNQKFGFEVGPVCFLG 1806
            DFGDQNQKFGFEVGPVCFLG
Sbjct: 1799 DFGDQNQKFGFEVGPVCFLG 1818


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 3782 bits (9807), Expect = 0.0
 Identities = 1767/1806 (97%), Positives = 1767/1806 (97%), Gaps = 39/1806 (2%)

Query: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60
            MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF
Sbjct: 1    MEPWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGF 60

Query: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120
            CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN
Sbjct: 61   CTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYN 120

Query: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180
            EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV
Sbjct: 121  EHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIV 180

Query: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240
            DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS
Sbjct: 181  DCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYS 240

Query: 241  PDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEA 300
            PDCDSSAPKAAQAQEPQIDE                                       A
Sbjct: 241  PDCDSSAPKAAQAQEPQIDE---------------------------------------A 261

Query: 301  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 360
            NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY
Sbjct: 262  NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLY 321

Query: 361  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 420
            ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG
Sbjct: 322  ENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 381

Query: 421  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 480
            AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP
Sbjct: 382  AYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLP 441

Query: 481  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 540
            GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP
Sbjct: 442  GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRP 501

Query: 541  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 600
            GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR
Sbjct: 502  GPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR 561

Query: 601  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 660
            GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP
Sbjct: 562  GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP 621

Query: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720
            GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP
Sbjct: 622  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681

Query: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780
            GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK
Sbjct: 682  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741

Query: 781  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840
            GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP
Sbjct: 742  GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801

Query: 841  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900
            GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP
Sbjct: 802  GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861

Query: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960
            GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT
Sbjct: 862  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 921

Query: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020
            GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD
Sbjct: 922  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 981

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080
            GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ
Sbjct: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041

Query: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140
            GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK
Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101

Query: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200
            GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161

Query: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260
            GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA
Sbjct: 1162 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1221

Query: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320
            GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP
Sbjct: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281

Query: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380
            GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1341

Query: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440
            GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP
Sbjct: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1401

Query: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500
            GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP
Sbjct: 1402 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1461

Query: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560
            GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG
Sbjct: 1462 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521

Query: 1561 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1620
            MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG
Sbjct: 1522 MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDG 1581

Query: 1621 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1680
            EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL
Sbjct: 1582 EYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKL 1641

Query: 1681 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1740
            LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE
Sbjct: 1642 LSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDE 1701

Query: 1741 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1800
            EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG
Sbjct: 1702 EMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVG 1761

Query: 1801 PVCFLG 1806
            PVCFLG
Sbjct: 1762 PVCFLG 1767


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 2921 bits (7573), Expect = 0.0
 Identities = 1371/1844 (74%), Positives = 1503/1844 (81%), Gaps = 53/1844 (2%)

Query: 6    SRWKTKRWLWDFT--VTTLALTFLFQAREVRGAAPVDVLKALDFHNSPEGISKTTGFCTN 63
            +RWK +  L      +  L L  L+     R A P D+LK LDFHN P+GI+KTTGFC  
Sbjct: 5    TRWKARSALRPGAPLLPPLLLLLLWAPPPSRAAQPADLLKVLDFHNLPDGITKTTGFCAT 64

Query: 64   RKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHG 123
            R++SKG D AYRV+K AQLSAPTKQL+P   FPEDFSIL TVK KKG Q+FL+SIYNE G
Sbjct: 65   RRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVKAKKGSQAFLVSIYNEQG 124

Query: 124  IQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCK 183
            IQQIG+E+GRSPVFL+EDHTGKP PEDYPLFR +N++DGKWHR+A+SV KK VT+I+DCK
Sbjct: 125  IQQIGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGKWHRIALSVHKKNVTLILDCK 184

Query: 184  KKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDC 243
            KKTTK LDRS+  ++D NGI VFGTRILDEEVFEGDIQQ L   D +AAYDYCEHYSPDC
Sbjct: 185  KKTTKFLDRSDHPMIDINGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAYDYCEHYSPDC 244

Query: 244  DSSAPKAAQAQEPQIDEYAPE-----DIIEYDYEYGE----------AEYKEAESVTEGP 288
            D++ P   Q+Q+P  DEY  E     +   Y+Y Y E             K  E+  E  
Sbjct: 245  DTAVPDTPQSQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETT 304

Query: 289  TVTEE-TIAQTEANIVDDFQE------------YNYGTMESYQTEAPRH--VSGTNEPNP 333
             V EE T   TEA  + +  E            Y+Y   E Y T +P      G  E NP
Sbjct: 305  EVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYDDLTYGEGEENP 364

Query: 334  VEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGE-----YDFYEYKE 388
             +   T+     E   S    S  +       +G D    ++G+  E      D   Y  
Sbjct: 365  DQP--TDPGAGAEIPTSTADTSNSSNPAPPPGEGADD---LEGEFTEETIRNLDENYYDP 419

Query: 389  YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAG 448
            Y D PTS P+E  GPG+PA  D     I G    GEKGQKGEPA++EPGML+EGPPGP G
Sbjct: 420  YYD-PTSSPSE-IGPGMPANQDTIYEGIGG--PRGEKGQKGEPAIIEPGMLIEGPPGPEG 475

Query: 449  PAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG---SK 505
            PAG+ GPPG  GPTG  GDPG+RGPPGRPGLPGADGLPGPPGTMLMLPFR+GG G   SK
Sbjct: 476  PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSK 535

Query: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
            GP +SAQE+QAQAILQQAR+ALRGP GPMGLTGRPGPVG PGS G KGE GD GPQGPRG
Sbjct: 536  GPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRG 595

Query: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625
            VQGPPGP GKPG+RGR G+DG RGMPG+ G KGDRGFDGL GLPG+KGHRG+ GP GPPG
Sbjct: 596  VQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG 655

Query: 626  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
            PPGDDG RG+DGE+GPRGLPGE GPRGLLGP+G PG PG PG+ G+DG PGPKGN+GPQG
Sbjct: 656  PPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG 715

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            EPGPPGQQGNPG QGLPGPQG IGPPGEKGP GKPGL G+PGADGPPGHPGKEG  GEKG
Sbjct: 716  EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775

Query: 746  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805
              GPPGPQGPIGYPGPRGVKGADG+RGLKG+KGEKGEDGFPGFKGDMG+KGDRGE+G  G
Sbjct: 776  GQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG 835

Query: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
            PRGEDGPEGPKGR GP GDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGANG
Sbjct: 836  PRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG 895

Query: 866  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925
            EKG RG  GKPGPRGQRGPTGPRG RG RG TGKPGPKG SGGDGP GPPGERGP GPQG
Sbjct: 896  EKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQG 955

Query: 926  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG 985
            P GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP GVVGPQGPTGETGP+GERG
Sbjct: 956  PTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERG 1015

Query: 986  HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG 1045
            HPGPPGPPGEQGLPG AGKEG KGDPGP G+ GKDGP GLRGFPG+RGLPG  GA GLKG
Sbjct: 1016 HPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKG 1075

Query: 1046 GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105
             EGP GPPGP GSPGERG AG AGPIG+PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG
Sbjct: 1076 NEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135

Query: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG 1165
            +QGPVGLPGPAGP G PGEDGDKGEIGEPGQKGSKGDKGE GPPGP G QGP+G PG +G
Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195

Query: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225
             DGEPGPRGQQG+FGQKGDEG RGFPGPPGP+GLQGLPGPPGEKGE GDVG MGPPGPPG
Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255

Query: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1285
            PRGP G  GADGPQGPPG +G+ G VGEKGEPGEAG PG PGE G  GPKGERGEKGE+G
Sbjct: 1256 PRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESG 1315

Query: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345
            P GAAGPPG KGPPGDDGPKG+PGPVGFPGDPGPPGEPGPAGQDG  GDKG+DG+PGQ G
Sbjct: 1316 PSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375

Query: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405
             PGP+GE GP GPPGKRGPPG AG EGRQGEKGAKGEAG EGPPGKTGP+GPQG  GKPG
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG 1435

Query: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465
            P+GLRGIPGPVGEQGLPG+ G DGPPGPMGPPGLPGLKGD G KGEKGHPGLIGLIGPPG
Sbjct: 1436 PDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPG 1495

Query: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525
            EQGEKGDRGLPG QGS G KG+ GI GP+GP+GPPGPPGLPGP GPKG KGS+GP G KG
Sbjct: 1496 EQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKG 1555

Query: 1526 DSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADAD---DNILDYSDGMEEIFGS 1582
            ++G PGPPG PGPPGEVIQPLPI +S +TRR+ +  Q   D   +N +DY+DGMEEIFGS
Sbjct: 1556 EAGHPGPPGPPGPPGEVIQPLPIQAS-RTRRNIDASQLLDDGNGENYVDYADGMEEIFGS 1614

Query: 1583 LNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFT 1642
            LNSLK +IE MK P+GTQ NPARTCKDLQL HPDFPDGEYW+DPNQGCS DSFKVYCNFT
Sbjct: 1615 LNSLKLEIEQMKRPLGTQQNPARTCKDLQLCHPDFPDGEYWVDPNQGCSRDSFKVYCNFT 1674

Query: 1643 SGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLL 1702
            +GG TC++PDKKSEG RI+SWPKE PGSWFSEFKRGKLLSY+D EGN + +VQMTFL+LL
Sbjct: 1675 AGGSTCVFPDKKSEGARITSWPKENPGSWFSEFKRGKLLSYVDAEGNPVGVVQMTFLRLL 1734

Query: 1703 TASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG 1762
            +ASA QN TYHC+QS AW D ++GSYDKALRFLGSNDEEMSYDNNP+I+ L DGCA++KG
Sbjct: 1735 SASAHQNVTYHCYQSVAWQDAATGSYDKALRFLGSNDEEMSYDNNPYIRALVDGCATKKG 1794

Query: 1763 YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1806
            Y+KTV+EI+TPK++QVPIVD+M NDFG+ +QKFGFEVGP CF+G
Sbjct: 1795 YQKTVLEIDTPKVEQVPIVDIMFNDFGEASQKFGFEVGPACFMG 1838


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 2474 bits (6413), Expect = 0.0
 Identities = 1171/1785 (65%), Positives = 1358/1785 (76%), Gaps = 89/1785 (4%)

Query: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYG 274
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +P+          
Sbjct: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQ---------- 249

Query: 275  EAEYKEAESVTEGPTVTEETIAQTEANIVDDFQEY----NYGTMESYQTEAPRHVSGTNE 330
                 +  S    P   E     TE+   D    Y      GT   YQ   P       E
Sbjct: 250  -----QQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTP------GE 298

Query: 331  PNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDF-YEYKEY 389
               + E      L  E  D Q   + D     +  +G       D   G YD+ Y Y + 
Sbjct: 299  EEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGG-----TDPPEGPYDYTYGYGDD 353

Query: 390  EDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 449
              + T     E GP + AET    +    HG  G KG+KGEPAV+EPGMLVEGPPGP GP
Sbjct: 354  YREET-----ELGPALSAET--AHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 406

Query: 450  AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG-GDGSKGPT 508
            AG++GPPG+QG  GP GDPG+RGPPGR GLPG+DG PGPPGT LMLPFR+G G G KGP 
Sbjct: 407  AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466

Query: 509  ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 568
            ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G KGESGD GPQGPRG QG
Sbjct: 467  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526

Query: 569  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628
              GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+KGHRG+ G QG PGPPG
Sbjct: 527  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586

Query: 629  DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG 688
            +DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+DGP GPKG++GPQGEPG
Sbjct: 587  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646

Query: 689  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 748
            PPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPPGHPGKEG  G KG  G
Sbjct: 647  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 706

Query: 749  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 808
            P GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+G+KGDRGEVG  G RG
Sbjct: 707  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 766

Query: 809  EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 868
            EDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGA+GEKG
Sbjct: 767  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 826

Query: 869  ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928
            ARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP GPPGERG  GPQGP G
Sbjct: 827  ARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG 886

Query: 929  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 988
            FPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQG  GETGP+GERGHPG
Sbjct: 887  FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 946

Query: 989  PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1048
            PPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGERGLPG  G PGLKG EG
Sbjct: 947  PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 1006

Query: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108
            P GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDGVQG
Sbjct: 1007 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 1066

Query: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168
            PVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPPG  GPVG PG AG DG
Sbjct: 1067 PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG 1126

Query: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228
            EPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE GDVGPMGPPGPPGPRG
Sbjct: 1127 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1186

Query: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288
            P GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV GP+GERGEKGE+G PG
Sbjct: 1187 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1246

Query: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
              GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  GD+GEDG+PGQPG PG
Sbjct: 1247 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1306

Query: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408
            P+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKTGPVGP GPAGKPGP+G
Sbjct: 1307 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1366

Query: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468
            LRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEKGHPGLIGLIGPPGEQG
Sbjct: 1367 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1426

Query: 1469 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1528
            EKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPKG KG+TGP G KG+ G
Sbjct: 1427 EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG 1486

Query: 1529 LPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYS------DGMEEIFGS 1582
            + GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +          G+EEIFGS
Sbjct: 1487 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGS 1546

Query: 1583 LNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFT 1642
            L+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT
Sbjct: 1547 LDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFT 1606

Query: 1643 SGGETCIYP-DKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKL 1701
            +GGETC+ P D  ++                         SY+D EG+ + +VQ+TFL+L
Sbjct: 1607 AGGETCVTPRDDVTQ------------------------FSYVDSEGSPVGVVQLTFLRL 1642

Query: 1702 LTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRK 1761
            L+ SA Q+ +Y C         S  + D  LR  G+N++E+S + +P++K   DGC +++
Sbjct: 1643 LSVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQ 1693

Query: 1762 GYEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1806
            G  +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+G
Sbjct: 1694 G--RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1736


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 2246 bits (5819), Expect = 0.0
 Identities = 1032/1424 (72%), Positives = 1161/1424 (81%), Gaps = 49/1424 (3%)

Query: 396  PPNEEFGPGVPAETDITETSI------NGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 449
            P +++  PG   E +I E+S+        HG  G KG+KGEPAV+EPGMLVEGPPGP GP
Sbjct: 263  PQSQDPTPG--EEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 320

Query: 450  AGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG-GDGSKGPT 508
            AG++GPPG+QG  GP GDPG+RGPPGR GLPG+DG PGPPGT LMLPFR+G G G KGP 
Sbjct: 321  AGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 380

Query: 509  ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG 568
            ++AQEAQAQAILQQAR+ALRGPPGPMG TGRPGP+G PGS G KGESGD GPQGPRG QG
Sbjct: 381  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440

Query: 569  PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628
              GP GK G+RGR GADG RGMPG+PG KGDRGFDGLPGLPG+KGHRG+ G QG PGPPG
Sbjct: 441  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500

Query: 629  DDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG 688
            +DG RG+DGEIGPRGLPGE+GPRGLLGP+G PG PG PG+ G+DGP GPKG++GPQGEPG
Sbjct: 501  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560

Query: 689  PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG 748
            PPGQQG PG QGLPGPQG IGP GEKGPQGKPGL G+PG+DGPPGHPGKEG  G KG  G
Sbjct: 561  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620

Query: 749  PPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRG 808
            P GPQGP+GYPGPRGVKG DG+RGLKG KGEKGEDGFPGFKGD+G+KGDRGEVG  G RG
Sbjct: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRG 680

Query: 809  EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKG 868
            EDGPEGPKGR GPTGDPGP G  GEKGKLGVPGLPGYPGRQGPKGS GFPGFPGA+GEKG
Sbjct: 681  EDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKG 740

Query: 869  ARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928
            ARG++GK GPRG+RGPTGPRG RG RG TGK G KGTSGGDGP GPPGERG  GPQGP G
Sbjct: 741  ARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNG 800

Query: 929  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 988
            FPGPKGPPGPPGKDGLPGHPGQRGE GFQGKTGPPGP GVVGPQG  GETGP+GERGHPG
Sbjct: 801  FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG 860

Query: 989  PPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1048
            PPGPPGEQGLPG AGKEG KGDPGP G  GKDGPAGLRGFPGERGLPG  G PGLKG EG
Sbjct: 861  PPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEG 920

Query: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108
            P GPPGP GSPGERG+AG+ GPIG PGRPGPQGPPG AGEKG PGEKGP GP GRDGVQG
Sbjct: 921  PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG 980

Query: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168
            PVGLPGPAGP G  GEDGDKGE+G+PGQKG+KG+KGE+GPPGPPG  GPVG PG AG DG
Sbjct: 981  PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG 1040

Query: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228
            EPG RG QG FG KGDEG RGF GPPGPIGLQGLPGP GEKGE GDVGPMGPPGPPGPRG
Sbjct: 1041 EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100

Query: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288
            P GPNGADGPQGPPG VG++G  GEKGEPGE+G+PG  GE GV GP+GERGEKGE+G PG
Sbjct: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1160

Query: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
              GPPG KGP GDDGPKGNPGPVGFPGDPGPPGE GP GQDG  GD+GEDG+PGQPG PG
Sbjct: 1161 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220

Query: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1408
            P+GE GPPGP GKRGP G+ G+EGRQG KGAKG+ GA G PGKTGPVGP GPAGKPGP+G
Sbjct: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1280

Query: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468
            LRG+PG VG+QG PGA GQ GPPGP+GPPGLPGL+GD G+KGEKGHPGLIGLIGPPGEQG
Sbjct: 1281 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG 1340

Query: 1469 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSG 1528
            EKGDRGLPG QGSPG KG+ GIPG +GP+GP GPPGLPGP GPKG KG+TGP G KG+ G
Sbjct: 1341 EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKG 1400

Query: 1529 LPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSD------GMEEIFGS 1582
            + GPPG PGPPGEVIQPLPI   KKTRR  +G +   +D  +          G+EEIFGS
Sbjct: 1401 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGS 1460

Query: 1583 LNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFT 1642
            L+SL+++IE M+ P GTQ +PARTC+DL+L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT
Sbjct: 1461 LDSLREEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCARDAFRVFCNFT 1520

Query: 1643 SGGETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLL 1702
            +GGETC+ P                     ++F      SY+D EG+ + +VQ+TFL+LL
Sbjct: 1521 AGGETCVTPRDD-----------------VTQF------SYVDSEGSPVGVVQLTFLRLL 1557

Query: 1703 TASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG 1762
            + SA Q+ +Y C         S  + D  LR  G+N++E+S + +P++K   DGC +++G
Sbjct: 1558 SVSAHQDVSYPC---------SGAARDGPLRLRGANEDELSPETSPYVKEFRDGCQTQQG 1608

Query: 1763 YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFLG 1806
              +TV+E+ TP ++Q+P++D   +D G   ++ G  +GPVCF+G
Sbjct: 1609 --RTVLEVRTPVLEQLPVLDASFSDLGAPPRRGGVLLGPVCFMG 1650



 Score = 1025 bits (2649), Expect = 0.0
 Identities = 613/1446 (42%), Positives = 749/1446 (51%), Gaps = 149/1446 (10%)

Query: 35   GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
            GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28   GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95   FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
            FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80   FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155  RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
            R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140  RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215  VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYG 274
            VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +P+   +      
Sbjct: 200  VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQ---QQPSRLH 256

Query: 275  EAEYKEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSG-TNEPNP 333
              + +E +S    P   EE +   E++++   +E  +G         PR + G   EP  
Sbjct: 257  RPQNQEPQSQDPTPGEEEEIL---ESSLLPPLEEAAHG---------PRGLKGEKGEPAV 304

Query: 334  VEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKP 393
            +E     E   G +           L     I G    +   G+ G          +  P
Sbjct: 305  LEPGMLVEGPPGPE-------GPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAP 357

Query: 394  TSPPNE-----EFGPG------------VPAETDITETSINGHGAYGEKGQKGEPAVV-- 434
              P         FG G              A+  + +  +   G  G  G  G P  +  
Sbjct: 358  GPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQ 417

Query: 435  --EPGMLVE----GPPGPAGPAGIMGPP---------GLQGPTGPPGDP---GDRGPPGR 476
               PG+  E    GP GP GP G+ GPP         G  G  G PGDP   GDRG  G 
Sbjct: 418  PGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 477

Query: 477  PGLP---------GADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIAL 527
            PGLP         GA GLPGPPG         G DG  GP     E+  + +L       
Sbjct: 478  PGLPGEKGHRGDTGAQGLPGPPGE----DGERGDDGEIGPRGLPGESGPRGLL-----GP 528

Query: 528  RGP---PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA 584
            +GP   PGP G+ G  GP G  GS G +GE G PG QG  G QG PGP G  G  G  G 
Sbjct: 529  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGL 644
             G  G+PG PG+ G  G  G  G PG KG++G  GPQGP G PG  G++G DG  G +G 
Sbjct: 589  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648

Query: 645  PGEAGP------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698
             GE G       +G +G +G  G  G PG  G DGP GPKG  GP G+PGPPG  G  G 
Sbjct: 649  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708

Query: 699  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGY 758
             G+PG  G  G  G KG  G PG  G  G  G  G  GK G  GE+G  GP G +GP G 
Sbjct: 709  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768

Query: 759  PGPRGVKGADGVRGLKGSKGEK------GEDGFPGFKGDM------GLKGDRGEVGQIGP 806
             G  G KG  G  G  G  GE+      G +GFPG KG        GL G  G+ G++G 
Sbjct: 769  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 828

Query: 807  RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP---GYPGRQGPKGSTGFPGFPGA 863
            +G+ GP GP G  GP G  G +G  GE+G  G PG P   G PG  G +G+ G PG PGA
Sbjct: 829  QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888

Query: 864  NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP------KGTSGGDGPPGPPGE 917
             G+ G  G+ G PG RG  G  G  G +G  GP+G PGP      +G +G  GP GPPG 
Sbjct: 889  PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR 948

Query: 918  RGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974
             GPQGP G     G PG KGP GP G+DG+ G  G  G  G  G  G  G  G VG  G 
Sbjct: 949  PGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQ 1008

Query: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034
             G  G  GE G PGPPGP G  G PGAAG +G  G  GPQG  G  G  G RGF G  G 
Sbjct: 1009 KGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGP 1068

Query: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094
             G QG PG  G +G  G  GP+G PG  G  G AGP    G  GPQGPPG  G  G PGE
Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP---NGADGPQGPPGGVGNLGPPGE 1125

Query: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP--- 1151
            KG  G +G  G+QG  G+ GP G  G  GE G  GE G PG KG  GD G  G PGP   
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1185

Query: 1152 PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE--- 1208
            PG  GP G  G  G DG  G RG+ G  GQ G  G  G  GPPGP+G +G  G PG    
Sbjct: 1186 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR 1245

Query: 1209 ---KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1265
               KG  GD G +G PG  GP GP GP G  GP G  G  GSVG  G  G  G+AG PGP
Sbjct: 1246 QGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGP 1305

Query: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325
             G  G+ G +G+ G KGE G PG  G  G  G  G+ G +G PGP G PG  G  G PG 
Sbjct: 1306 VGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGA 1365

Query: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385
            +G  G G      G PG PGP GP G  G  GP G +            GEKG +G  G 
Sbjct: 1366 SGPIGPG------GPPGLPGPAGPKGAKGATGPGGPK------------GEKGVQGPPGH 1407

Query: 1386 EGPPGK 1391
             GPPG+
Sbjct: 1408 PGPPGE 1413


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 2243 bits (5813), Expect = 0.0
 Identities = 1025/1395 (73%), Positives = 1148/1395 (82%), Gaps = 41/1395 (2%)

Query: 419  HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPG 478
            HG  G KG+KGEPAV+EPGMLVEGPPGP GPAG++GPPG+QG  GP GDPG+RGPPGR G
Sbjct: 269  HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328

Query: 479  LPGADGLPGPPGTMLMLPFRYG-GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 537
            LPG+DG PGPPGT LMLPFR+G G G KGP ++AQEAQAQAILQQAR+ALRGPPGPMG T
Sbjct: 329  LPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYT 388

Query: 538  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597
            GRPGP+G PGS G KGESGD GPQGPRG QG  GP GK G+RGR GADG RGMPG+PG K
Sbjct: 389  GRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 448

Query: 598  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
            GDRGFDGLPGLPG+KGHRG+ G QG PGPPG+DG RG+DGEIGPRGLPGE+GPRGLLGP+
Sbjct: 449  GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508

Query: 658  GTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717
            G PG PG PG+ G+DGP GPKG++GPQGEPGPPGQQG PG QGLPGPQG IGP GEKGPQ
Sbjct: 509  GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568

Query: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777
            GKPGL G+PG+DGPPGHPGKEG  G KG  GP GPQGP+GYPGPRGVKG DG+RGLKG K
Sbjct: 569  GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHK 628

Query: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837
            GEKGEDGFPGFKGD+G+KGDRGEVG  G RGEDGPEGPKGR GPTGDPGP G  GEKGKL
Sbjct: 629  GEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKL 688

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 897
            GVPGLPGYPGRQGPKGS GFPGFPGA+GEKGARG++GK GPRG+RGPTGPRG RG RG T
Sbjct: 689  GVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGAT 748

Query: 898  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957
            GK G KGTSGGDGP GPPGERG  GPQGP GFPGPKGPPGPPGKDGLPGHPGQRGE GFQ
Sbjct: 749  GKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808

Query: 958  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017
            GKTGPPGP GVVGPQG  GETGP+GERGHPGPPGPPGEQGLPG AGKEG KGDPGP G  
Sbjct: 809  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868

Query: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077
            GKDGPAGLRGFPGERGLPG  G PGLKG EGP GPPGP GSPGERG+AG+ GPIG PGRP
Sbjct: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928

Query: 1078 GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK 1137
            GPQGPPG AGEKG PGEKGP GP GRDGVQGPVGLPGPAGP G  GEDGDKGE+G+PGQK
Sbjct: 929  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988

Query: 1138 GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197
            G+KG+KGE+GPPGPPG  GPVG PG AG DGEPG RG QG FG KGDEG RGF GPPGPI
Sbjct: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048

Query: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257
            GLQGLPGP GEKGE GDVGPMGPPGPPGPRGP GPNGADGPQGPPG VG++G  GEKGEP
Sbjct: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108

Query: 1258 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1317
            GE+G+PG  GE GV GP+GERGEKGE+G PG  GPPG KGP GDDGPKGNPGPVGFPGDP
Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168

Query: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1377
            GPPGE GP GQDG  GD+GEDG+PGQPG PGP+GE GPPGP GKRGP G+ G+EGRQG K
Sbjct: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 1378 GAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPP 1437
            GAKG+ GA G PGKTGPVGP GPAGKPGP+GLRG+PG VG+QG PGA GQ GPPGP+GPP
Sbjct: 1229 GAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPP 1288

Query: 1438 GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPL 1497
            GLPGL+GD G+KGEKGHPGLIGLIGPPGEQGEKGDRGLPG QGSPG KG+ GIPG +GP+
Sbjct: 1289 GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348

Query: 1498 GPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1557
            GP GPPGLPGP GPKG KG+TGP G KG+ G+ GPPG PGPPGEVIQPLPI   KKTRR 
Sbjct: 1349 GPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRS 1408

Query: 1558 TEGMQADADDNILDYSD------GMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQ 1611
             +G +   +D  +          G+EEIFGSL+SL+++IE M+ P GTQ +PARTC+DL+
Sbjct: 1409 VDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSLREEIEQMRRPTGTQDSPARTCQDLK 1468

Query: 1612 LSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSWPKEKPGSW 1671
            L HP+ PDGEYW+DPNQGC+ D+F+V+CNFT+GGETC+ P                    
Sbjct: 1469 LCHPELPDGEYWVDPNQGCARDAFRVFCNFTAGGETCVTPRDD----------------- 1511

Query: 1672 FSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1731
             ++F      SY+D EG+ + +VQ+TFL+LL+ SA Q+ +Y C         S  + D  
Sbjct: 1512 VTQF------SYVDSEGSPVGVVQLTFLRLLSVSAHQDVSYPC---------SGAARDGP 1556

Query: 1732 LRFLGSNDEEMSYDNNPFIKTLYDGCASRKGYEKTVIEINTPKIDQVPIVDVMINDFGDQ 1791
            LR  G+N++E+S + +P++K   DGC +++G  +TV+E+ TP ++Q+P++D   +D G  
Sbjct: 1557 LRLRGANEDELSPETSPYVKEFRDGCQTQQG--RTVLEVRTPVLEQLPVLDASFSDLGAP 1614

Query: 1792 NQKFGFEVGPVCFLG 1806
             ++ G  +GPVCF+G
Sbjct: 1615 PRRGGVLLGPVCFMG 1629



 Score =  699 bits (1803), Expect = 0.0
 Identities = 417/920 (45%), Positives = 471/920 (51%), Gaps = 149/920 (16%)

Query: 765  KGADGVRGLKGSKGEKG-------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKG 817
            + A G RGLKG KGE          +G PG +G  GL G  G  G  GP G+ G  GP G
Sbjct: 266  QAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 818  RA---GPTGDPGPSGQA-----------GEKGKL--------------------GVPGLP 843
            RA   G  G PGP G +           G+KG +                    G PG  
Sbjct: 326  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 385

Query: 844  GYPGRQGPKGSTGFPGFPGANGE---KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900
            GY GR GP G  G PG  G +G+   +G RG  G  GP G+ G  G  G+ GARG  G P
Sbjct: 386  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445

Query: 901  GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD------GLPGHPGQRGET 954
            G KG  G DG PG PGE+G +G  G  G PGP G  G  G D      GLPG  G RG  
Sbjct: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505

Query: 955  GFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011
            G +G  G PGP GV    GPQGP G  GP GE G PG  G PG QGLPG  G  G  G+ 
Sbjct: 506  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565

Query: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071
            GPQ   GK G  G+ G  G  G PG +G PG KG +GP GP GP+G PG RG  G  G  
Sbjct: 566  GPQ---GKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR 622

Query: 1072 GL------------PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1119
            GL            PG  G  G  G  GE G PG +G  GP G  G  GP G PGP G  
Sbjct: 623  GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682

Query: 1120 GS------------PGEDGDKGEIGEPGQKGSKGDK------------GENGPPGPPGLQ 1155
            G             PG  G KG +G PG  G+ G+K            GE GP GP G +
Sbjct: 683  GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742

Query: 1156 GP------VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209
            GP       GA G +GGDG  GP G++G+ G +G  G  G  GPPGP G  GLPG PG++
Sbjct: 743  GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802

Query: 1210 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA------GNP 1263
            GE G  G  GPPGPPG  GPQG  G  GP G  G  G  G  GE+G PG A      G+P
Sbjct: 803  GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP------ 1317
            GPPG  G  GP G RG  GE G PG AG PG K   G++GP G PGP G PG+       
Sbjct: 863  GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK---GNEGPSGPPGPAGSPGERGAAGSG 919

Query: 1318 ---GPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374
               GPPG PGP G  G  G+KG  G+ G  GP G  G  GP G PG  GPPG AG +G +
Sbjct: 920  GPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDK 979

Query: 1375 GE---------KGAKGEAGAEGPPGKTGPV---------------GPQGPAGKPGPEGLR 1410
            GE         KG KGE G  GPPG  GPV               GPQG  G  G EG R
Sbjct: 980  GEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTR 1039

Query: 1411 GI---PGPVGEQGLPGAAGQDGPP---GPMGPPGLPGLKGDP---GSKGEKGHPGLIGLI 1461
            G    PGP+G QGLPG +G+ G     GPMGPPG PG +G     G+ G +G PG +G +
Sbjct: 1040 GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNL 1099

Query: 1462 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521
            GPPGE+GE G+ G PG QG PG KG  G  G  G  G PG PG PGP+GP G+ G  G  
Sbjct: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159

Query: 1522 GQKGDSGLPGPPGSPGPPGE 1541
            G  G  G PGPPG  GP G+
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQ 1179



 Score =  240 bits (613), Expect = 8e-63
 Identities = 113/230 (49%), Positives = 166/230 (72%), Gaps = 8/230 (3%)

Query: 35  GAAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGT 94
           GA PVDVL+AL F + P+G+ +  G C        +D AYRV++ AQLSAPT+QLFPGG 
Sbjct: 28  GAPPVDVLRALRFPSLPDGVRRAKGICP-------ADVAYRVARPAQLSAPTRQLFPGG- 79

Query: 95  FPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLF 154
           FP+DFS+L  V+ + G+Q+ LL++Y+  G++Q+G+E+GR   FL+ED TG+P P   P+F
Sbjct: 80  FPKDFSLLTVVRTRPGLQAPLLTLYSAQGVRQLGLELGRPVRFLYEDQTGRPQPPSQPVF 139

Query: 155 RTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEE 214
           R +++ADGKWHRVA++V+ ++VT+IVDCKK+ T+PL RS R ++DT+G+ +FG RILDEE
Sbjct: 140 RGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEE 199

Query: 215 VFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPE 264
           VFEGD+Q+  I    +AAY+ CE    +C+    +  Q Q+P   + +P+
Sbjct: 200 VFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQ 249



 Score =  240 bits (612), Expect = 1e-62
 Identities = 145/355 (40%), Positives = 165/355 (46%), Gaps = 86/355 (24%)

Query: 1266 PGEAGVGGPKGERGEKGE----------AGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315
            P      GP+G +GEKGE           GPPG  GP G  GPP   G +GNPGPVG PG
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPP---GIQGNPGPVGDPG 319

Query: 1316 DPGPPGEPGPAGQDGV-----------------GGDKGED-------------------- 1338
            + GPPG  G  G DG                  GGDKG                      
Sbjct: 320  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 379

Query: 1339 ---------------GDPGQP------------GPPGPSGEAGPPGPPGKRGPPGAAGAE 1371
                           G PG P            GP GP G  GPPG  G+RG  GA GA 
Sbjct: 380  GPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439

Query: 1372 GRQGEKGAKGEAGAEGPP------GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425
            G  G+ G KG+ G +G P      G  G  G QG  G PG +G RG  G +G +GLPG +
Sbjct: 440  GMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES 499

Query: 1426 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485
            G  G  GP GPPG+P   G PG +G  G  G  G +GP GE G  G +G PGTQG PG +
Sbjct: 500  GPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 556

Query: 1486 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
            G  G  G  GP G PG PG+PG  GP G+ G  GP G KG+ G  GP G  G PG
Sbjct: 557  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPG 611



 Score =  234 bits (598), Expect = 4e-61
 Identities = 147/342 (42%), Positives = 164/342 (47%), Gaps = 28/342 (8%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV-------EPGMLVEGPPG 445
            P  PP    GP  P   D  +    G G  G  G+KGEP          EPG  V+GP G
Sbjct: 1071 PPGPPGPR-GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPG--VKGPRG 1127

Query: 446  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505
              G  G  G PG  GP GP G  GD GP G PG  G  G PGPPG         G DG+K
Sbjct: 1128 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGE----GGPRGQDGAK 1183

Query: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
            G     ++ +             GPPGP+G  G  G  G  G  G KG  GDPG  G  G
Sbjct: 1184 GD--RGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241

Query: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625
              GP GP G  GK   PG DG RG+PG  G +G  G  G  G PG  G  G  G +G  G
Sbjct: 1242 KTGPVGPAGPAGK---PGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAG 1298

Query: 626  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
              G+ G  G  G IGP G  GE G RGL GP+G+PG  G+ G+ G  GP GP        
Sbjct: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGP-------- 1350

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727
              GPPG  G  GP+G  G  GP GP GEKG QG PG  G PG
Sbjct: 1351 -GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 13/56 (23%)

Query: 1503 PGLPGPQGPKGNKGS-------------TGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            P      GP+G KG               GP G +G +GL GPPG  G PG V  P
Sbjct: 263  PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP 318


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 2115 bits (5479), Expect = 0.0
 Identities = 1025/1771 (57%), Positives = 1224/1771 (69%), Gaps = 58/1771 (3%)

Query: 36   AAPVDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTF 95
            A PVDVLKAL       G+ +  GFC  R  +   D A+R+ + + L  PT +LFP G F
Sbjct: 29   ADPVDVLKALGVQGGQAGVPEGPGFCPQR--TPEGDRAFRIGQASTLGIPTWELFPEGHF 86

Query: 96   PEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR 155
            PE+FS+L T++ +   QS LLSIY+E G +Q+G+ +G +   L     G P     PL +
Sbjct: 87   PENFSLLITLRGQPANQSVLLSIYDERGARQLGLALGPALGLL-----GDPFR---PLPQ 138

Query: 156  TVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEV 215
             VN+ DG+WHRVA+S++ + VT++ DC+ +   P+       +   G+TV GT+ L E+ 
Sbjct: 139  QVNLTDGRWHRVAVSIDGEMVTLVADCEAQP--PVLGHGPRFISIAGLTVLGTQDLGEKT 196

Query: 216  FEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGE 275
            FEGDIQ+ LI+ DP+AA+  CE Y PDCD+ AP A  A + + +   P          G+
Sbjct: 197  FEGDIQELLISPDPQAAFQACERYLPDCDNLAPAATVAPQGEPETPRPR-------RKGK 249

Query: 276  AEYKEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVE 335
             + ++     +G    +     T +   D  +      +   +T AP        P P  
Sbjct: 250  GKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAPNL-----PPTPTP 304

Query: 336  EIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTS 395
             + T    TG                N  I  R  D     +LG  +    +E E+   S
Sbjct: 305  LVVTSTVTTGL---------------NATILERSLDPDSGTELGTLETKAAREDEEGDDS 349

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455
                  GP   A    + T        GEKG KGEPAV+E G   EGPPG  GP G++GP
Sbjct: 350  T----MGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGP 405

Query: 456  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
             G  GP G PGDPG  GP G PG+PG DG+ GPPGT++M+PF++ G   KGP +S Q+AQ
Sbjct: 406  SGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQ 465

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575
            AQA+LQQ +++++GPPGP+GLTGRPGPVG PG  G KGE G  GPQGPRG+QGP GP G+
Sbjct: 466  AQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR 525

Query: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGE 635
             GK GRPGADG RG+PG+ G KGDRGFDGLPGLPG+KG RG+ G  G PGPPG+DG RG 
Sbjct: 526  VGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGA 585

Query: 636  DGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGN 695
            +G  GP G  GE GPRGLLGPRG+PG  G+PG+ G+DG PG KGN+GP GEPGPPGQQGN
Sbjct: 586  EGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGN 645

Query: 696  PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 755
             G QGLPGPQG IG PGEKGP G PG+ GLPG+DGP GHPG EG +GEKGA GPPG  GP
Sbjct: 646  HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGP 705

Query: 756  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGP 815
             GYPGPRGVKG  G RGL+G KGEKGEDGFPGFKGD+GLKGD+G+ G  GPRGEDGPEGP
Sbjct: 706  PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGP 765

Query: 816  KGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK 875
            KG+AG  G+ GP G AGEKGKLGVPGLPGYPGR GPKGS GFPG  G  GEKG  G  G+
Sbjct: 766  KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQ 825

Query: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
            PG  G+RGP G RG RG  G TG+PGPKG  G DG PG PGE+G  G QGP GFPGPKGP
Sbjct: 826  PGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGP 885

Query: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995
            PG  GKDG PGHPGQRGE GFQG+TGPPGP GV+GPQG TGE GP+GERG PGPPGPPGE
Sbjct: 886  PGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGE 945

Query: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055
            QGLPG  G+EGAKG+ GP G  GK+GPAGLRGFPG +G PG  G  GLKG +GP GP G 
Sbjct: 946  QGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA 1005

Query: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115
             GSPGERG  G AG IGLPG+ G +GP GPAG+KG+ GE+GP GP G+DG+ GP+G  GP
Sbjct: 1006 NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP 1065

Query: 1116 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQ 1175
             G AG  GE+GDKG++G PG KGSKGDKG+ GPPG PG++GP G PG  G DG  G RG 
Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125

Query: 1176 QGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGA 1235
             G+FGQKGD+G RGF G  GP GLQGLPGPPGEKGE GDVG MGP G PGPRGPQGP G+
Sbjct: 1126 PGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS 1185

Query: 1236 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1295
            +G  G PG VG  G VGEKGE G+AG+PGPPG  G+ GPKG+ GEKG++GP GAAGPPG 
Sbjct: 1186 EGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK 1245

Query: 1296 KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGP 1355
            KGPPG+DG KG+ GP G PGD GPPG+PG +G DG  G+KG+ GD G PGPPG SGE G 
Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305

Query: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415
            PGPPGKRGP G  G EGR+GEKGAKGE G +GPPG+TGP+G +GP G+ GPEGLRGIPGP
Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGP 1365

Query: 1416 VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL 1475
            VGE GL GA GQ GPPGP+GP GLPGLKGD G KGEKGH GLIGLIGPPGE GEKGD+GL
Sbjct: 1366 VGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGL 1425

Query: 1476 PGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1535
            PG QG PG KGD G PGP G LG PGPPG+ GP G KG+KGS G  G +GD+G  GPPG 
Sbjct: 1426 PGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGP 1485

Query: 1536 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKF 1595
            PG P E       L   + RR    +     +       G+EE+  SL SL  ++E ++ 
Sbjct: 1486 PGAPAE-------LHGLRRRRRFVPVPLPVVEG------GLEEVLASLTSLSLELEQLRR 1532

Query: 1596 PMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKS 1655
            P GT   P   C +L  +HP  PDGEYWIDPNQGC+ DSF+V+CNFT+GGETC+YPDKK 
Sbjct: 1533 PPGTAERPGLVCHELHRNHPHLPDGEYWIDPNQGCARDSFRVFCNFTAGGETCLYPDKKF 1592

Query: 1656 EGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQNFTYHCH 1715
            E V+++SW KEKPG W+S F+RGK  SY+D +G+ +N+VQ+ FLKLL+A+ARQNFTY C 
Sbjct: 1593 EIVKLASWSKEKPGGWYSTFRRGKKFSYVDADGSPVNVVQLNFLKLLSATARQNFTYSCQ 1652

Query: 1716 QSAAWYDVSSGSYDKALRFLGSNDEEMSYDNN--PFIKTLYDGCASRKGYEKTVIEINTP 1773
             +AAW D ++G Y  + RFLG+N EE+S++      +    DGC  RKG  KT+ E ++ 
Sbjct: 1653 NAAAWLDEATGDYSHSARFLGTNGEELSFNQTTAATVSVPQDGCRLRKGQTKTLFEFSSS 1712

Query: 1774 KIDQVPIVDVMINDFGDQNQKFGFEVGPVCF 1804
            +   +P+ DV   DFG  NQKFGFE+GPVCF
Sbjct: 1713 RAGFLPLWDVAATDFGQTNQKFGFELGPVCF 1743


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 1229 bits (3179), Expect = 0.0
 Identities = 685/1442 (47%), Positives = 808/1442 (56%), Gaps = 65/1442 (4%)

Query: 397  PNEEFGPGVP-AETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455
            P   FG   P   TD+   S    G  G KGQKGEP  ++  +  +GPPGP GPAG  GP
Sbjct: 78   PEIPFGECCPICPTDLATAS----GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGP 133

Query: 456  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
             G +G  G  G PG RG  G PG PG  G PGPPG     P   GG+ +        E  
Sbjct: 134  RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG--PPGLGGNFAAQMAGGFDEKA 191

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP 572
              A L      ++GP GPMG  G PGP G PG  G +G   E G+PG  GP G +GPPGP
Sbjct: 192  GGAQLG----VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP 247

Query: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 632
             GKPG  G  G  G  G  G PG +G RGF G PGLPG KGHRG  G  G  G  G  G+
Sbjct: 248  PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307

Query: 633  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 692
            +GE G  G  G PG  GPRGL G RG  G  G  G  G DG PGP G  GP G  G PG 
Sbjct: 308  KGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367

Query: 693  QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 752
             G PG +G  GP G  GP G +GP+G+PG  G PG  G  G+PG +G  G KG+ G PG 
Sbjct: 368  PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 753  QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGP 812
             G  G+PGPRG  G  G  G  G KG+ GE G  GFKG+ G KG   E G  GP+G  GP
Sbjct: 428  AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG---EPGPAGPQGAPGP 484

Query: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG---PKGSTGFPGFPGANGEKGA 869
             G +G+ G  G+PG  G  G  G+ G PG  G+PG+ G   PKG+ G  G  G  G KGA
Sbjct: 485  AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544

Query: 870  RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGF 929
             G  G+PG  G  G  G  G  G  GP GK GP G  G DG PGPPG +G +G  G +GF
Sbjct: 545  NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 930  PGPKGPPGPPGK---DGLPGHPGQRGETGFQGKTG---PPGPGGVVGPQGPTGETGPIGE 983
            PGPKG  G PGK    GLPG PG RG  G  G+TG   PPGP G  G +G  G  GP G 
Sbjct: 605  PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 984  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1043
            +G PGPPGPPGE       GK G +G PG  G  G  GP G RGFPGERG PGAQG  G 
Sbjct: 665  QGLPGPPGPPGE------GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718

Query: 1044 KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGP 1100
            +G  G  G  GP G+ G  G  G  GP GL G PG +G     GP G++G  GEKGP+G 
Sbjct: 719  RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGA 778

Query: 1101 AGRD---GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1157
             G+D   G+ GP+G PGPAG  G  GE G  G  G  G +G+ G++GE GPPGP G  GP
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGD 1214
             GA      DG+PG +G+QG  GQKGD GA G  GP   PGP G  G+ GP G +G  G 
Sbjct: 839  PGA------DGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGP 1274
             G  G PG  G  GP G NG  GP GPPG  G  G  G +G+ G  G  G PG  G  GP
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 1275 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP---GPVGFPGDPGPPGEPGPAGQDGV 1331
             GE+GE G+ GP GA GPPG +G  G  G  G P   G  GFPG PGP GEPG  G  G 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 1332 GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGK 1391
             GD+G  G  G PG  GP+GE G  G PG  GPPG  GA G +G++G  G  GA G PG 
Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072

Query: 1392 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE 1451
             G  GP GP GK G  G  G  GP+G  G  GA G  GP GP G     G  G+PG +G 
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD---KGEAGEPGERGL 1129

Query: 1452 KGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP 1511
            KGH G  GL G PG  G  GD+G  G  G  G +G  G  GP+G  G  G PG  GP GP
Sbjct: 1130 KGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGP 1189

Query: 1512 KGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILD 1571
            +G  G TGPAG  G+ G PGPPG PGP  ++     +   +K     + M+AD     L 
Sbjct: 1190 RGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLR 1249

Query: 1572 YSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCS 1631
              D   E+  +L SL   IE ++ P G++ NPARTC+DL+L HP++  G+YWIDPNQGC+
Sbjct: 1250 QHDA--EVDATLKSLNNQIESIRSPEGSRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCT 1307

Query: 1632 GDSFKVYCNFTSGGETCIYPDKKSEGVR--ISSWPKEKPGSWFSEFKRGKL-LSYLD--V 1686
             D+ KV+CN  + GETC+YP+  +   +   SS  KEK   WF E   G    SY D  +
Sbjct: 1308 LDAMKVFCNMET-GETCVYPNPANVPKKNWWSSKSKEKKHIWFGETINGGFHFSYGDDNL 1366

Query: 1687 EGNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD- 1745
              N+ N VQMTFL+LL+    QN TYHC  S A+ D ++G+  KAL   GSND E+  + 
Sbjct: 1367 APNTAN-VQMTFLRLLSTEGSQNITYHCKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEG 1425

Query: 1746 NNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVC 1803
            N+ F  T L DGC    G + KTVIE  + K  ++PI+D+   D G   Q+FG ++GPVC
Sbjct: 1426 NSRFTYTALKDGCTKHTGKWGKTVIEYRSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVC 1485

Query: 1804 FL 1805
            FL
Sbjct: 1486 FL 1487



 Score =  709 bits (1831), Expect = 0.0
 Identities = 421/961 (43%), Positives = 472/961 (49%), Gaps = 163/961 (16%)

Query: 744  KGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE-------------DGFPGFKG 790
            K  L P  P G      P  +  A G  G KG KGE G+              G  G +G
Sbjct: 73   KDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG 132

Query: 791  DMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP----------------------- 827
              G +GD+GE G  GPRG DG  G  G  GP G PGP                       
Sbjct: 133  PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192

Query: 828  -------SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR---------- 870
                    G  G  G  G PG  G PG QG +G+ G PG PG +G  G R          
Sbjct: 193  GAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG 252

Query: 871  --GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG 928
              G AGKPG  G+RGP GP+G+RG  G  G PG KG  G  G  G  GE G  G +G  G
Sbjct: 253  DDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESG 312

Query: 929  FPGPKGPPGPPGKDGLPGHPGQ---RGETGFQGKTGPPGPGGVVGPQGPT---------- 975
             PG  G PGP G  GLPG  G+    G  G +G  G PGP G  GP GP           
Sbjct: 313  SPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG 372

Query: 976  --GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERG 1033
              GE GP G RG  G  GP GE G PG+ G  GA G+PG  GI G  G AG  G  G  G
Sbjct: 373  AKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPG 432

Query: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE----- 1088
             PG +G PG +G  GP GP G  G PG  G  G  GP G PG  GPQG PGPAGE     
Sbjct: 433  FPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492

Query: 1089 -KGAPGEKGPQGP------------AGRDGVQGPVGLP---GPAGPAGSPGEDGDKGEIG 1132
             +G PG  GP GP             G+DG+ GP G P   GP+G AG  G +GD G  G
Sbjct: 493  ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 552

Query: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGP---RGQQGMFGQKGDEGARG 1189
            EPG  G++G  G  G  GP G  GP GAPG  G  G PGP   RGQ G+ G  G +GA G
Sbjct: 553  EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612

Query: 1190 FPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG 1249
             PG  G  GL G PG  G  G++G+ G  GPPGP GP G +G  GA GP G  G  G  G
Sbjct: 613  EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 672

Query: 1250 GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA---AGPPGAKGPPGDDGPKG 1306
              GE G+PG+ G PG  G  G+ GP+GERG  GE G PGA    GP G  G PG DGPKG
Sbjct: 673  PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKG 732

Query: 1307 NPGPVGFPGDPGPP---GEPGPAGQDGVGGDKGEDGDPGQPGP----------------- 1346
              GP G PG  GPP   G PG  G  G+ G KG+ GD G+ GP                 
Sbjct: 733  ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792

Query: 1347 ----------------------------PGPSGEAGPPGPPGKRGPPGA---AGAEGRQG 1375
                                        PG  GE GPPGP G  GPPGA    GA+G QG
Sbjct: 793  PPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852

Query: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435
            E G KG+AGA GP G +G  GPQGP G  GP+G RG  GP G  G PGAAG+ GPPG  G
Sbjct: 853  EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNG 912

Query: 1436 PPGLP------------GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
             PG P            G +GD G  G  G PGL G  GPPGE+GE GD G  G +G PG
Sbjct: 913  NPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972

Query: 1484 AK---GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
             +   G  GI G  G  G  G PGLPGP G  G +G+ G +G +G  G  GPPG  GP G
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAG 1032

Query: 1541 E 1541
            E
Sbjct: 1033 E 1033


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 1226 bits (3172), Expect = 0.0
 Identities = 677/1415 (47%), Positives = 799/1415 (56%), Gaps = 60/1415 (4%)

Query: 423  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA 482
            G KGQKGEP  ++  +  +GPPGP GPAG  GP G +G  G  G PG RG  G PG PG 
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 483  DGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP 542
             G PGPPG     P   GG+ +        E    A L      ++GP GPMG  G PGP
Sbjct: 92   PGPPGPPGPPG--PPGLGGNFAAQMAGGFDEKAGGAQLG----VMQGPMGPMGPRGPPGP 145

Query: 543  VGGPGSSGAKG---ESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGD 599
             G PG  G +G   E G+PG  GP G +GPPGP GKPG  G  G  G  G  G PG +G 
Sbjct: 146  AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA 205

Query: 600  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659
            RGF G PGLPG KGHRG  G  G  G  G  G++GE G  G  G PG  GPRGL G RG 
Sbjct: 206  RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265

Query: 660  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719
             G  G  G  G DG PGP G  GP G  G PG  G PG +G  GP G  GP G +GP+G+
Sbjct: 266  TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325

Query: 720  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779
            PG  G PG  G  G+PG +G  G KG+ G PG  G  G+PGPRG  G  G  G  G KG+
Sbjct: 326  PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385

Query: 780  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 839
             GE G  GFKG+ G KG   E G  GP+G  GP G +G+ G  G+PG  G  G  G+ G 
Sbjct: 386  TGEPGIAGFKGEQGPKG---EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 840  PGLPGYPGRQG---PKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896
            PG  G+PG+ G   PKG+ G  G  G  G KGA G  G+PG  G  G  G  G  G  GP
Sbjct: 443  PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 897  TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK---DGLPGHPGQRGE 953
             GK GP G  G DG PGPPG +G +G  G +GFPGPKG  G PGK    GLPG PG RG 
Sbjct: 503  QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 954  TGFQGKTG---PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 1010
             G  G+TG   PPGP G  G +G  G  GP G +G PGPPGPPGE       GK G +G 
Sbjct: 563  PGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE------GGKPGDQGV 616

Query: 1011 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070
            PG  G  G  GP G RGFPGERG PGAQG  G +G  G  G  GP G+ G  G  G  GP
Sbjct: 617  PGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGP 676

Query: 1071 IGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRD---GVQGPVGLPGPAGPAGSPGE 1124
             GL G PG +G     GP G++G  GEKGP+G  G+D   G+ GP+G PGPAG  G  GE
Sbjct: 677  PGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGE 736

Query: 1125 DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1184
             G  G  G  G +G+ G++GE GPPGP G  GP GA      DG+PG +G+QG  GQKGD
Sbjct: 737  VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA------DGQPGAKGEQGEAGQKGD 790

Query: 1185 EGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241
             GA G  GP   PGP G  G+ GP G +G  G  G  G PG  G  GP G NG  GP GP
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850

Query: 1242 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1301
            PG  G  G  G +G+ G  G  G PG  G  GP GE+GE G+ GP GA GPPG +G  G 
Sbjct: 851  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910

Query: 1302 DGPKGNP---GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGP 1358
             G  G P   G  GFPG PGP GEPG  G  G  GD+G  G  G PG  GP+GE G  G 
Sbjct: 911  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970

Query: 1359 PGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE 1418
            PG  GPPG  GA G +G++G  G  GA G PG  G  GP GP GK G  G  G  GP+G 
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 1419 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
             G  GA G  GP GP G     G  G+PG +G KGH G  GL G PG  G  GD+G  G 
Sbjct: 1031 SGPAGARGIQGPQGPRGD---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP 1087

Query: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP 1538
             G  G +G  G  GP+G  G  G PG  GP GP+G  G TGPAG  G+ G PGPPG PGP
Sbjct: 1088 AGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP 1147

Query: 1539 PGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMG 1598
              ++     +   +K     + M+AD     L   D   E+  +L SL   IE ++ P G
Sbjct: 1148 GIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA--EVDATLKSLNNQIESIRSPEG 1205

Query: 1599 TQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGV 1658
            ++ NPARTC+DL+L HP++  G+YWIDPNQGC+ D+ KV+CN  + GETC+YP+  +   
Sbjct: 1206 SRKNPARTCRDLKLCHPEWKSGDYWIDPNQGCTLDAMKVFCNMET-GETCVYPNPANVPK 1264

Query: 1659 R--ISSWPKEKPGSWFSEFKRGKL-LSYLD--VEGNSINMVQMTFLKLLTASARQNFTYH 1713
            +   SS  KEK   WF E   G    SY D  +  N+ N VQMTFL+LL+    QN TYH
Sbjct: 1265 KNWWSSKSKEKKHIWFGETINGGFHFSYGDDNLAPNTAN-VQMTFLRLLSTEGSQNITYH 1323

Query: 1714 CHQSAAWYDVSSGSYDKALRFLGSNDEEMSYD-NNPFIKT-LYDGCASRKG-YEKTVIEI 1770
            C  S A+ D ++G+  KAL   GSND E+  + N+ F  T L DGC    G + KTVIE 
Sbjct: 1324 CKNSIAYLDEAAGNLKKALLIQGSNDVEIRAEGNSRFTYTALKDGCTKHTGKWGKTVIEY 1383

Query: 1771 NTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1805
             + K  ++PI+D+   D G   Q+FG ++GPVCFL
Sbjct: 1384 RSQKTSRLPIIDIAPMDIGGPEQEFGVDIGPVCFL 1418



 Score =  858 bits (2218), Expect = 0.0
 Identities = 501/1163 (43%), Positives = 580/1163 (49%), Gaps = 133/1163 (11%)

Query: 376  GDLGEYDFYEYKEYEDKPTSP--PNEEFGPGVPAETDITET-SINGHGAYGEKGQKGEPA 432
            GD GE      +  + +P +P  P     PG P    +    +    G + EK    +  
Sbjct: 69   GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 128

Query: 433  VVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP------GDRGPPGRPGLPGADGLP 486
            V++  M   GP GP GPAG  GP G QG  G PG+P      G RGPPG PG PG DG  
Sbjct: 129  VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 487  GPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 546
            G PG                                 +   RGPPGP G  G PG  G P
Sbjct: 189  GKPG---------------------------------KAGERGPPGPQGARGFPGTPGLP 215

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP 606
            G  G +G  G  G +G  G  G  G +G PG+ G PG  G RG+PGE G  G  G  G  
Sbjct: 216  GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGAR 275

Query: 607  GLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQP 666
            G  G  G  G  GP GP G PG  G  G  GE GP    G  GP G  GPRG PG PG P
Sbjct: 276  GNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP---TGARGPEGAQGPRGEPGTPGSP 332

Query: 667  GMAGVDGPPGPKGNMGPQGEPGPP---GQQGNPGPQGLPGPQGPIGP------------- 710
            G AG  G PG  G  G +G  G P   G  G PGP+G PGPQG  GP             
Sbjct: 333  GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392

Query: 711  --PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD 768
               GE+GP+G+PG AG  GA GP G  GK G  GE G +GP GP G  G PG RG  G D
Sbjct: 393  GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452

Query: 769  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR---GEDGPEGPKGRAGPTGDP 825
            G+ G KG+ GE+G  G  G KG  G  G  GE G  G R   G  G  GP+G+ GP+G P
Sbjct: 453  GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512

Query: 826  GPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA---RGVAGKPGPRGQR 882
            G  G+ G  G  G  G PG  G  GPKG+ G PG  G  G  GA   RG+ GK G  G  
Sbjct: 513  GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAA 572

Query: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942
            GP GP G  G RG  G PGP G  G  GPPGPPGE G  G QG  G  G  G  GP G+ 
Sbjct: 573  GPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGER 632

Query: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002
            G PG  G  G  G QG  G PG  G  GP+G +G  GP G +G PG  G PGE+G  G A
Sbjct: 633  GFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIA 692

Query: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSP 1059
            G +G +GD G +G  G  G  G RG  G  G PG  GA G KG  GP GP G     G+P
Sbjct: 693  GPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP 752

Query: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK------GPQGPAGRDGVQGPVGL- 1112
            GERG  G  GP G  G PG  G PG  GE+G  G+K      GPQGP+G  G QGP G+ 
Sbjct: 753  GERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 812

Query: 1113 -----------------PGPAGPAGSPGEDGDKGEIGEP---GQKGSKGDKGENGPP--- 1149
                             PG AG  G PG +G+ G  G P   G+ G KG +G++GPP   
Sbjct: 813  GPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRA 872

Query: 1150 GPPGLQGPVGAP---------GIAGGDGEPGPR---GQQGMFGQKGDEGARGFPGPPGPI 1197
            G PGLQGP G P         G +G +G PGP+   GQ+G+ G  G  G RGFPG PGP 
Sbjct: 873  GEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932

Query: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE- 1256
            G  G  G PG  G+ G  GP+GPPG  GP G  G  G+ G  GPPG  G+ G  G++GE 
Sbjct: 933  GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGET 992

Query: 1257 -----PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311
                 PG  G PG PG AG  G +G+RGE G  GP G +GP GA+G  G  GP+G+ G  
Sbjct: 993  GAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEA 1052

Query: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371
            G PG+ G  G  G  G  G+ G  G  GD G  GP GPSG  GPPGP          G  
Sbjct: 1053 GEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP---------VGPS 1103

Query: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431
            G+ G  G  G  G  GP G++G  GP GP G PGP G  G PGP    G+  +A     P
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGP----GIDMSAFAGLGP 1159

Query: 1432 GPMGPPGLPGLKGDPGSKGEKGH 1454
               GP  L  ++ D  + G + H
Sbjct: 1160 REKGPDPLQYMRADQAAGGLRQH 1182



 Score =  380 bits (977), Expect = e-105
 Identities = 218/502 (43%), Positives = 248/502 (49%), Gaps = 97/502 (19%)

Query: 1130 EIGEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185
            ++ +PG KG KG+ G+     GP GPPG QGP G  G  G  G+ G +G  G  G+ G+ 
Sbjct: 27   DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 1186 GARGFPGPPGPIGLQGLPGPPGEKGE---------------------NGDVGPMGPPGPP 1224
            G  G PGPPGP    G PGPPG  G                       G +GPMGP GPP
Sbjct: 87   GTPGNPGPPGP---PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 143

Query: 1225 GPRGPQGPNGAD---------------GPQGPPGSVGSVGGVGEKGEPGEAGNPGP---- 1265
            GP G  GP G                 GP+GPPG  G  G  GE G+PG+AG  GP    
Sbjct: 144  GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 1266 -----PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320
                 PG  G+ G KG RG  G  G  G AG PG KG  G  G  G+PGP+G  G PG  
Sbjct: 204  GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP------------GPPGKRGPPGAA 1368
            G  GPA   G  G +G DG PG  GPPGP G AG P            GP G RGP GA 
Sbjct: 264  GRTGPA---GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP------------- 1415
            G  G  G  G+ G AGA G PG  G  G +G AG PG  G  G PGP             
Sbjct: 321  GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 380

Query: 1416 -----VGEQGLPGAAGQDGP---PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ 1467
                  GE G+ G  G+ GP   PGP GP G PG  G+ G +G +G PG +G IGPPGE+
Sbjct: 381  GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440

Query: 1468 GEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---------PGPPGLPGPQGPKGNKGST 1518
            G  G+RG PG  G  G KG  G  GP+G  GP         PG PGLPG +G  G  G  
Sbjct: 441  GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500

Query: 1519 GPAGQKGDSGLPGPPGSPGPPG 1540
            GP G+ G SG PG  G PGPPG
Sbjct: 501  GPQGKVGPSGAPGEDGRPGPPG 522


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 1199 bits (3103), Expect = 0.0
 Identities = 670/1436 (46%), Positives = 785/1436 (54%), Gaps = 99/1436 (6%)

Query: 423  GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGP---PGRPGL 479
            G KGQKGEP +V     + G PGPAGP G  GP   +G  GP G PG RGP    G PG+
Sbjct: 110  GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP---RGERGPKGRPGPRGPQGIDGEPGV 166

Query: 480  PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA--------QAQAILQQARIALRGPP 531
            PG  G PGPPG     P   G DG   P  SAQ A         +Q  L    +   GP 
Sbjct: 167  PGQPGAPGPPGH----PSHPGPDGLSRP-FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR 221

Query: 532  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 591
            GP GL G+    GG G +G  GE GDPGP GP G +GP GP GKPG+ G PG +G  G  
Sbjct: 222  GPQGLQGQQ---GGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEV 278

Query: 592  GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 651
            G  G+ G RGF G PGLPG KGHRG +G +GP G  G  G +GE G  GP G  G  GPR
Sbjct: 279  GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338

Query: 652  GL------LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQ 705
            G+      LGP+G PG  G  GM G  GP GP G  G  G PG PG +G  GP G  GP+
Sbjct: 339  GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPE 398

Query: 706  GPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVK 765
            GP G  GE GP G  G  GLPGA G  G PG +G +G  G  GPPG  GP G PGP+G  
Sbjct: 399  GPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGST 458

Query: 766  GADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD---RGEVGQIGPRGEDGPEGPKGRAGPT 822
            G  G+R      G+ G+ G PGFKG+ G KG+    G  G IGP GE+G  GP+G  G  
Sbjct: 459  GPQGIR------GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTV 512

Query: 823  GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQR 882
            G PGP G+ G  G  G PG  G P   GPKG+ G  G  G++G KG++G  G+PG  G  
Sbjct: 513  GPPGPVGERGAPGNRGFPGSDGLP---GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP 569

Query: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942
            G  G  G+ G +GP GK GP G  G DG PGPPG  G +G  G +G PGPKG  G PGK 
Sbjct: 570  GARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK- 628

Query: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002
                 PG+ G  G  G+ G PG  G VGP GP G  G  GERG  GPPGP G QGLPG  
Sbjct: 629  -----PGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 1003 GKEGAKGDPGPQGISGKD------GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1056
            G  G  G PG QG+ G        GP G RG PGERG PG  G PG KG  G  GP GP 
Sbjct: 684  GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743

Query: 1057 GSPGERGSAGTAGPIGLPGRPGPQ---GPPGPAGEKGAPGEKGPQGPAGRDGVQ---GPV 1110
            GSPG  G+ G  GP GL G PG +   G PGP G++G  GEKG +G AG DG +   GP+
Sbjct: 744  GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPL 803

Query: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1170
            G PGPAGP G  GE G +G +G PG +G+ G +GENGP G  G  GP G  G  G  GEP
Sbjct: 804  GPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEP 863

Query: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL------PGPPGEKGENGDVGPMGPPGPP 1224
            G  GQ+G  G  G +G  G PGP GP G+ GL       GPPG  G  G  G +GPPGP 
Sbjct: 864  GEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 1225 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1284
            G  GP GP G  G +GPPG  G  G  G  G+ G AG PG PG+      KG+ GE G+ 
Sbjct: 924  GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD------KGDPGEDGQP 977

Query: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344
            GP G  GP G  G  G  G  G  G  G PG PGP G PG  G  G  GDKG  G  G P
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404
            G  GP GE GP GP G  G PG  GA G +G++G  G AG    PG  G  G  GP G P
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL---PGSQGAPGTPGPVGAP 1094

Query: 1405 GPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPP 1464
            G  G RG PG  G  G PG AG+ G PGP GP G  G  GD G +G+KGH G  GL G P
Sbjct: 1095 GDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP 1154

Query: 1465 GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK 1524
            G  G  G++   G+ G PG  G  G PGP GP G  G PG  GP GP G +GS G AG +
Sbjct: 1155 GPPGPNGEQ---GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE 1211

Query: 1525 GDSGLPGPPGSPGPPGEVIQPLPILSSKKTR-------RHTEGMQADADDNILDYSDGME 1577
            G  G PGPPG PGPPG +   L  +               TE   A  D N  D      
Sbjct: 1212 GPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTD-----P 1266

Query: 1578 EIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKV 1637
             +  +L SL   IE M+ P G++ +PARTC DL+L H     GEYWIDPNQG   D+ KV
Sbjct: 1267 GVHATLKSLSSQIETMRSPDGSKKHPARTCDDLKLCHSAKQSGEYWIDPNQGSVEDAIKV 1326

Query: 1638 YCNFTSGGETCIYPDKKSEGVRISSW-----PKEKPGSWFSEFKRGKLLSYLDVEGNSIN 1692
            YCN  + GETCI  +  S  V   +W     P  KP  +  +  RG   +Y D +  +  
Sbjct: 1327 YCNMET-GETCISANPSS--VPRKTWWASKSPDNKPVWYGLDMNRGSQFAYGDHQSPNTA 1383

Query: 1693 MVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIK- 1751
            + QMTFL+LL+  A QN TY C  S  + D  + +  KA+   G+ND ++  + N   + 
Sbjct: 1384 ITQMTFLRLLSKEASQNITYICKNSVGYMDDQAKNLKKAVVLKGANDLDIKAEGNIRFRY 1443

Query: 1752 -TLYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1805
              L D C+ R G   KTV E  T  + ++PI+D+   D G  +Q+FG E+GPVCF+
Sbjct: 1444 IVLQDTCSKRNGNVGKTVFEYRTQNVARLPIIDLAPVDVGGTDQEFGVEIGPVCFV 1499



 Score =  690 bits (1781), Expect = 0.0
 Identities = 398/880 (45%), Positives = 450/880 (51%), Gaps = 98/880 (11%)

Query: 394  TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM 453
            T PP     PG+P        +I   G  G KG  G P          GPPG AGP G  
Sbjct: 407  TGPPGPVGSPGLPG-------AIGTDGTPGAKGPTGSPG-------TSGPPGSAGPPGSP 452

Query: 454  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQE 513
            GP G  GP G  G PGD G PG  G  G  G PGP G    +    G +G +GP      
Sbjct: 453  GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG-PPGEEGKRGP------ 505

Query: 514  AQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT 573
                    +      GPPGP+G  G PG  G PGS G  G  G  G +GP G  GP G  
Sbjct: 506  --------RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQ 557

Query: 574  GKPGKRGRPGADGGRGMPGEPGAKGDR---------GFDGLPGLPGDKGHRGERGPQGPP 624
            G PG+ G PG  G RG+ G PG +G           G DG PG PG  G RG+ G  G P
Sbjct: 558  GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLP 617

Query: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGL---LGPRGTPGAPGQPGMAGVDGPPGPKGNM 681
            GP G  G  G+ GE G  G+PG+ G  G    +GP G  G PG  G  G  GPPGP G  
Sbjct: 618  GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQ 677

Query: 682  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741
            G  G PGPPG+ G PG QG+PG  G +GP G +G +G PG  G PG  G P         
Sbjct: 678  GLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLP--------- 728

Query: 742  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD---MGLKGDR 798
            GEKG  G  GP GP G PGP G  G  G  GL+G  GE+G  G PG KGD   +G KG  
Sbjct: 729  GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788

Query: 799  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858
            G  G  G RG  GP GP G AGPTG+ G  G  G  G  G  G PG  G  GP G+ GF 
Sbjct: 789  GTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFA 848

Query: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGTSGGDGPPGP- 914
            G  G +G+ G +G  G+PG +G  G  GP+   GS G  GP G PG KG  G  GPPG  
Sbjct: 849  GPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT 908

Query: 915  --PGERGPQGPQGPVGFPGPKGPPGPPGKDGLP---GHPGQRGETGFQGKTGPP-GPG-- 966
              PG  G  GP GP G PGP GP G PGK+G P   G PG  G  G +G  GPP GPG  
Sbjct: 909  GFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDK 968

Query: 967  ------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD 1020
                  G  GP GP G  G  G+RG  G PG  GE+G+PG  G  G  G  GP G +G  
Sbjct: 969  GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL------P 1074
            GP G  G PG     G  G PG +G  G  G PG  G+ GERG  G  GP GL      P
Sbjct: 1029 GPPGPVGPPGSN---GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAP 1085

Query: 1075 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP 1134
            G PGP G PG AG++G PG +GP GP GR G +   GLPGP GP G  G+ GD+G+ G+ 
Sbjct: 1086 GTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKR---GLPGPQGPRGDKGDHGDRGDRGQK 1142

Query: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPP 1194
            G +G  G +G  GPPGP G QG  G PG  G  G PGP          G  G  G PGP 
Sbjct: 1143 GHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGP---------VGPSGKEGNPGPL 1193

Query: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1234
            GPI      GPPG +G  G+ GP GPPG PGP GP GP G
Sbjct: 1194 GPI------GPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  145 bits (367), Expect = 3e-34
 Identities = 99/242 (40%), Positives = 109/242 (45%), Gaps = 53/242 (21%)

Query: 393  PTSPPNE-----EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPA 447
            P  PP       E GP  PA  D T       GA GE+G +G+P          G PG  
Sbjct: 1033 PVGPPGSNGPVGEPGPEGPAGNDGTP---GRDGAVGERGDRGDPGPA-------GLPGSQ 1082

Query: 448  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD-GSKG 506
            G  G  GP G  G  G  GDPG RGP G PG  G  GLPGP G     P    GD G +G
Sbjct: 1083 GAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG-----PRGDKGDHGDRG 1137

Query: 507  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 566
                                 RG  G  G TG  G  G PG +G +G +G PGP GPR  
Sbjct: 1138 D--------------------RGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPR-- 1175

Query: 567  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 626
             GPPGP G  GK G PG  G  G PG  G+ G+ G +G PG P         GP GPPGP
Sbjct: 1176 -GPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP---------GPPGPPGP 1225

Query: 627  PG 628
            PG
Sbjct: 1226 PG 1227


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 1193 bits (3087), Expect = 0.0
 Identities = 660/1394 (47%), Positives = 762/1394 (54%), Gaps = 71/1394 (5%)

Query: 445  GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 504
            G  GP G  GP G +GP GPPG  G  G PG PG PG  G PGPPG              
Sbjct: 109  GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGL------------- 155

Query: 505  KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQ 561
             G   + Q +          I++ GP GP G  G PGP G PG  G +G   E G+PG  
Sbjct: 156  -GGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGAS 214

Query: 562  GPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621
            GP G +GPPGP GK G  G  G  G  G  G PG +G RG  G  GLPG KGHRG  G  
Sbjct: 215  GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 622  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 681
            G  G  G  G +GE G  G  G PG+ GPRGL G RG PGAPG  G  G DG  G  G  
Sbjct: 275  GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 682  GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741
            GP G  GPPG  G  G +G  GPQGP G  G +G +G+PG  G  GA GP G+PG +GQ 
Sbjct: 335  GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 742  GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEV 801
            G KGA G PG  G  G+PG RG  G  G  G  G KG  GE G PG KGD G KG+ G V
Sbjct: 395  GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454

Query: 802  G---QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858
            G     GP GE+G  G +G  GPTG PGP G+ G  G  G PG  G  G   PKG  G  
Sbjct: 455  GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG---PKGPAGER 511

Query: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918
            G PG  G KG+ G AG+PG  G  G  G  GS G+ GP GK GP G +G DG PGPPG  
Sbjct: 512  GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571

Query: 919  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 978
            G +G  G +GFPGPKG  G PGK       G+RG  G  G  GP G  G  G QGP G  
Sbjct: 572  GARGQAGVMGFPGPKGAAGEPGK------AGERGVPGPPGAVGPAGKDGEAGAQGPPGPA 625

Query: 979  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK------DGPAGLRGFPGER 1032
            GP GERG  GP G PG QGLPG AG  G  G PG QG+ G        G  G RGFPGER
Sbjct: 626  GPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGER 685

Query: 1033 GL---PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1089
            G+   PG  G  G  G  G  G  G  G+PG  GS G  G  G+PG  G  G PGP G++
Sbjct: 686  GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDR 745

Query: 1090 GAPGEKGPQGPAGRDGVQG---PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGEN 1146
            G  G KG  G  G+DGV+G   P+G PGPAG  G  GE G  G  G  G +G+ GD+GE 
Sbjct: 746  GDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEP 805

Query: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1206
            GPPGP G  GP GA G  G  GEPG  G +   G  G  G  G  GPPGPIG  G PG  
Sbjct: 806  GPPGPAGFAGPPGADGQPGAKGEPGDAGAK---GDAGPPGPAGPAGPPGPIGNVGAPGAK 862

Query: 1207 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1266
            G +G  G  G  G PG  G  GP GP+G  GP GPPG  G  GG G +GE G AG PG  
Sbjct: 863  GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922

Query: 1267 GEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP---PGEP 1323
            G  G  GP GE+G       PGA GP GA G PG  G  G  G VG PG  G    PG P
Sbjct: 923  GPPGPPGPAGEKGS------PGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK--- 1380
            GP+G+ G  G  G  G+ G PGP GP G AGPPG  G+ G PGA G+ GR G  GAK   
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036

Query: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440
            GE G  GPPG  G  G  GP G  G  G RG  GP G  G  G  G  GP GP GP G  
Sbjct: 1037 GETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096

Query: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500
            G  G+ G +G KGH G  GL GPPG  G  G++G  G  G  G +G    PG AG  G  
Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP---PGSAGAPGKD 1153

Query: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560
            G  GLPGP GP G +G TG AG  G  G PGPPG PGPP        +    + + H  G
Sbjct: 1154 GLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGG 1213

Query: 1561 MQADADD-NILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPD 1619
                ADD N++   D   E+  +L SL Q IE+++ P G++ NPARTC+DL++ H D+  
Sbjct: 1214 RYYRADDANVV--RDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKS 1271

Query: 1620 GEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVR---ISSWPKEKPGSWFSE-F 1675
            GEYWIDPNQGC+ D+ KV+CN  + GETC+YP + S   +   IS  PK+K   WF E  
Sbjct: 1272 GEYWIDPNQGCNLDAIKVFCNMET-GETCVYPTQPSVAQKNWYISKNPKDKRHVWFGESM 1330

Query: 1676 KRGKLLSYLDVEGNSINM-VQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKALRF 1734
              G    Y     +  ++ +Q+TFL+L++  A QN TYHC  S A+ D  +G+  KAL  
Sbjct: 1331 TDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLL 1390

Query: 1735 LGSNDEEMSYDNNP--FIKTLYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDFGDQ 1791
             GSN+ E+  + N         DGC S  G + KTVIE  T K  ++PI+DV   D G  
Sbjct: 1391 QGSNEIEIRAEGNSRFTYSVTVDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAP 1450

Query: 1792 NQKFGFEVGPVCFL 1805
            +Q+FGF+VGPVCFL
Sbjct: 1451 DQEFGFDVGPVCFL 1464



 Score =  651 bits (1680), Expect = 0.0
 Identities = 383/853 (44%), Positives = 427/853 (50%), Gaps = 93/853 (10%)

Query: 397  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV----EPGMLVE-------GPPG 445
            P+   GPG P             G+ G+ G KGEP  V     PG   E       G PG
Sbjct: 417  PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPG 476

Query: 446  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505
            P               TG PG PG+RG PG  G PGADG+ GP G         G  G  
Sbjct: 477  P---------------TGLPGPPGERGGPGSRGFPGADGVAGPKGP----AGERGSPGPA 517

Query: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
            GP  S  EA              G PG  GL G  G  G PGS G  G++G PGP G  G
Sbjct: 518  GPKGSPGEA--------------GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563

Query: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625
              GPPGP G  G+ G  G  G +G  GEPG  G+RG  G PG  G  G  GE G QGPPG
Sbjct: 564  RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623

Query: 626  PPGDDGMRGEDGEIGP---RGLPGEAGPRGLLGPRGTPGAPGQ---------------PG 667
            P G  G RGE G  G    +GLPG AGP G  G  G  G PG                PG
Sbjct: 624  PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683

Query: 668  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP---IGPPGEKGPQGKPGLAG 724
              GV GPPGP G  G  G PG  G +G+ G  G PG QG     G PGE+G  G PG  G
Sbjct: 684  ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 725  LPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784
              G  GP G  G  G+ G +G  GP GP GP G PG +G  G  G  G  G++G  G+ G
Sbjct: 744  DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 785  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844
             PG  G  G  G  G  GQ G +GE G  G KG AGP G  GP+G  G  G +G PG  G
Sbjct: 804  EPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863

Query: 845  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904
              G  GP G+TGFPG  G  G  G  G AG PGP G  G  G +G RG  GP G+PG  G
Sbjct: 864  ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 905  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964
              G   PPGP GE+G  G  GP G PG  GP G  G+ G+ G PGQRGE GF G    PG
Sbjct: 924  PPG---PPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL---PG 977

Query: 965  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024
            P G  G QGP+G +   GERG PGP GPPG  G PG +G+EGA   PG +G  G+DG  G
Sbjct: 978  PSGEPGKQGPSGAS---GERGPPGPMGPPGLAGPPGESGREGA---PGAEGSPGRDGSPG 1031

Query: 1025 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1084
             +G  GE G  G  GAPG  G  GP GP G  G  GE G AG AGP+G  G  GP GP G
Sbjct: 1032 AKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG 1091

Query: 1085 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKG 1144
            P G+KG  GE+G +G  G  G     GL GP GP GSPGE          G  G+ G  G
Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFS---GLQGPPGPPGSPGEQ---------GPSGASGPAG 1139

Query: 1145 ENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP----IGLQ 1200
              GPPG  G  G  G  G+ G  G PGPRG+ G  G  G  G  G PGPPGP        
Sbjct: 1140 PRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFS 1199

Query: 1201 GLPGPPGEKGENG 1213
             LP PP EK  +G
Sbjct: 1200 FLPQPPQEKAHDG 1212


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 1117 bits (2890), Expect = 0.0
 Identities = 648/1396 (46%), Positives = 753/1396 (53%), Gaps = 102/1396 (7%)

Query: 448  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG-SKG 506
            GPAG  GP G +GP GPPG  G+ GP G PG PG    PGPPG       +Y G G   G
Sbjct: 33   GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGP---PGPPGLGGNFAAQYDGKGVGLG 89

Query: 507  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGV 566
            P                 + L GP GP G  G PGP G  G +G  GE G  GP G RG 
Sbjct: 90   P---------------GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGP 134

Query: 567  QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGP 626
             GPPG  G+ G  G+PG  G RG+ G  GA   RGF G PGLPG KG RG  G  G  G 
Sbjct: 135  AGPPGKAGEDGHPGKPGRPGERGVVGPQGA---RGFPGTPGLPGFKGIRGHNGLDGLKGQ 191

Query: 627  PGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE 686
            PG  G++GE G  G  G PG+ G RGL G RG  GAPG  G  G DG  GP G  GP G 
Sbjct: 192  PGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS 251

Query: 687  PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 746
             GPPG  G PGP+G  G  G  GP G  GP+G+ GL GL G  GPPG+PG  G +G KGA
Sbjct: 252  AGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGA 311

Query: 747  LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP 806
             G PG  G  G PGPRG+ G  G  G  G++G  GE G  G KG+ G KG+ G  G  GP
Sbjct: 312  AGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGP 371

Query: 807  ---RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
                GE+G  GP G AG  G PGP G  G  G  G+PG  G  G  GP GS G  G  G 
Sbjct: 372  PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431

Query: 864  NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923
               +G  G AG+PG  G  GP G  GS G  GP GK GP G  G DG PGP G  G +G 
Sbjct: 432  ---RGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGE 488

Query: 924  QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 983
             G +GFPGPKGP G PGK+G  GH       G  G  G PGP G  G QGP G  G  G 
Sbjct: 489  PGNIGFPGPKGPTGDPGKNGDKGH------AGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542

Query: 984  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1043
            +G  GPPGPPG QGLPG +G  G  G PG +G+ G+ G  G  G  GERG PG  GA G 
Sbjct: 543  KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602

Query: 1044 KG---GEGPQGPPGPVGSPGERG------SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094
             G     GP GPPGP G+ GE G      +AG +GP GLPG  G  G PG  GEKG PG 
Sbjct: 603  TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL 662

Query: 1095 KGPQGPAGRDGVQGP---VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1151
            +G  G  GRDG +G    VG PGPAG  G  GE G  G  G  G +GS G++GE GP GP
Sbjct: 663  RGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGP 722

Query: 1152 PGLQGPVGA---PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208
             G  GP GA   PG  G  G  GP+G+ G+ G  G  GA G  GP GP      PGP G 
Sbjct: 723  NGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP------PGPAGS 776

Query: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG------EAGN 1262
            +G+ G  G  G PG  G  GP GP+G  GP GPPG  G  G  G +G+ G      E G 
Sbjct: 777  RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836

Query: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322
             GPPG AG  GP GE G    AGPPG  GP G  G PG  G  G+ G  G PG  G  GE
Sbjct: 837  VGPPGFAGEKGPSGEAGT---AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGE 893

Query: 1323 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
            PGP G  G  G +G  G  G PG  G  GEAG  G PG  GPPG  G  G +GE+G  G 
Sbjct: 894  PGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGN 953

Query: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
             G  G  G  GP GP GPAGK G  G  G  GPV      G AG  GP GP GP G+ G 
Sbjct: 954  IGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPV------GPAGAVGPRGPSGPQGIRGD 1007

Query: 1443 KGDPGSKGEKGHPGL---IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1499
            KG+PG KG +G PGL    GL G PG  G  GD+G PG+ G  G +G  G  GPAG  G 
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067

Query: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTE 1559
             G PG  GP G +G +G  GPAG       PGPPG PGPPG        +S        +
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGP------PGPPGPPGPPG--------VSGGGYDFGYD 1113

Query: 1560 G--MQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDF 1617
            G   +AD   +         E+  +L SL   IE +  P G++ NPARTC+DL+LSHP++
Sbjct: 1114 GDFYRADQPRSAPSLRPKDYEVDATLKSLNNQIETLLTPEGSRKNPARTCRDLRLSHPEW 1173

Query: 1618 PDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSW---PKEKPGSWFSE 1674
              G YWIDPNQGC+ D+ KVYC+F S GETCI    + E +   +W    K+K   W  E
Sbjct: 1174 SSGYYWIDPNQGCTMDAIKVYCDF-STGETCI--RAQPENIPAKNWYRSSKDKKHVWLGE 1230

Query: 1675 -FKRGKLLSYLDVEG--NSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1731
                G    Y +VEG  +     Q+ F++LL   A QN TYHC  S A+ D  +G+  KA
Sbjct: 1231 TINAGSQFEY-NVEGVTSKEMATQLAFMRLLANYASQNITYHCKNSIAYMDEETGNLKKA 1289

Query: 1732 LRFLGSNDEEM-SYDNNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDF 1788
            +   GSND E+ +  N+ F  T L DGC+ +   + KT+IE  T K  ++P +D+   D 
Sbjct: 1290 VILQGSNDVELVAEGNSRFTYTVLVDGCSKKTNEWGKTIIEYKTNKPSRLPFLDIAPLDI 1349

Query: 1789 GDQNQKFGFEVGPVCF 1804
            G  +Q+F  ++GPVCF
Sbjct: 1350 GGADQEFFVDIGPVCF 1365



 Score =  753 bits (1943), Expect = 0.0
 Identities = 470/1092 (43%), Positives = 532/1092 (48%), Gaps = 166/1092 (15%)

Query: 387  KEYEDKPTSPPNEEFGPGVP-------AETDITETSINGHGAYGEKGQKGEP-AVVEPGM 438
            ++ ED PT PP     PG P       A+ D     + G G  G  G +G P A   PG 
Sbjct: 52   RDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGL-GPGPMGLMGPRGPPGAAGAPGP 110

Query: 439  L-VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP------PGT 491
               +GP G  G  G  GP G +GP GPPG  G+ G PG+PG PG  G+ GP      PGT
Sbjct: 111  QGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGT 170

Query: 492  MLMLPFR-----YGGDGSKG----PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP 542
              +  F+      G DG KG    P +  +           +   RG PG  G  G PGP
Sbjct: 171  PGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGP 230

Query: 543  VGG------------------------PGSSGAKGE------SGDPGPQGPR------GV 566
             G                         PG+ G KGE      +G  GP GPR      G+
Sbjct: 231  AGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGL 290

Query: 567  QGPPGPTGKPGKR---------------GRPGADGGRGMPGEPGAKGDRGFDGLPGLP-- 609
             GP GP G PG                 G PG  G RG+PG  GA G  G  GL G P  
Sbjct: 291  SGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGP 350

Query: 610  -------GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 662
                   G+KG  G  GPQGPPGP G++G RG +GE G  G PG  G RG  G RG PGA
Sbjct: 351  AGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGA 410

Query: 663  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 722
             G+   AGV GPPG +G  GP G  GP G  G PG  GL GP+G  G PG  GP GK G 
Sbjct: 411  DGR---AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGP 467

Query: 723  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV------------ 770
             GLPG DG PG  G  G  GE G +G PGP+GP G PG  G KG  G+            
Sbjct: 468  VGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGN 527

Query: 771  ---------RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ---------------IGP 806
                     +G++G KGE+G  G PGF+G  G  G  GEVG+                GP
Sbjct: 528  NGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGP 587

Query: 807  RGEDGPEGPKGRAGPT---GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
            RGE GP G  G AGPT   G  GPSG  G  G  G PG+ G  G  GP G +G PG  GA
Sbjct: 588  RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647

Query: 864  NGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923
             G  G +G  G+PG RG+ G  G  G+RGA G  G PGP G +G  G  G  G  GP GP
Sbjct: 648  AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707

Query: 924  QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 983
            +G  G  G  GP GP G  G  G  GQ G  G +G  GP G  GVVGP GP G  GP G 
Sbjct: 708  RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP 767

Query: 984  RGHPGPP------GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1037
             G PGP       GPPG  G PGAAG+    G PGP GISG  GP G  G  G RG  G 
Sbjct: 768  NGPPGPAGSRGDGGPPGMTGFPGAAGR---TGPPGPSGISGPPGPPGPAGKEGLRGPRGD 824

Query: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1097
            QG  G  G  G  GPPG  G  G  G AGTAGP   PG PGPQG  G  G  G PG +G 
Sbjct: 825  QGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGP---PGTPGPQGLLGAPGILGLPGSRGE 881

Query: 1098 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1157
            +   G  GV G VG PGP G AG PG  G  G +G PG  G+ G+ G +G P        
Sbjct: 882  R---GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNP-------- 930

Query: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP 1217
             G  G  G DG+PG +G++G  G  G  GA G PGP GP+   G  G  G +GE G  GP
Sbjct: 931  -GNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPV---GPAGKHGNRGETGPSGP 986

Query: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1277
            +GP G  GPRGP GP G  G +G PG  G  G  G KG  G  G PG  G  G  G  G 
Sbjct: 987  VGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGS 1046

Query: 1278 RGEKGEAGPPGAAGP---------PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328
             G  G  GP G +GP         PG  GP G  GP+G+ GP    G PGPPG PGP G 
Sbjct: 1047 VGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPA---GPPGPPGPPGPPGV 1103

Query: 1329 DGVGGDKGEDGD 1340
             G G D G DGD
Sbjct: 1104 SGGGYDFGYDGD 1115



 Score =  477 bits (1227), Expect = e-134
 Identities = 279/626 (44%), Positives = 319/626 (50%), Gaps = 100/626 (15%)

Query: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055
            Q L     ++G  GD GP+               GERG PG  G  G  G  GP GPPGP
Sbjct: 23   QSLQEETVRKGPAGDRGPR---------------GERGPPGPPGRDGEDGPTGPPGPPGP 67

Query: 1056 VGSPGERGSAGT----------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105
             G PG  G+              GP+GL    GP+GPPG AG  G  G +GP G  G  G
Sbjct: 68   PGPPGLGGNFAAQYDGKGVGLGPGPMGL---MGPRGPPGAAGAPGPQGFQGPAGEPGEPG 124

Query: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL------QGPVG 1159
              GP G  GPAGP G  GEDG  G+ G PG++G  G +G  G PG PGL      +G  G
Sbjct: 125  QTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNG 184

Query: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219
              G+ G  G PG +G+ G  G+ G  G  G  G PG  G  G PGP G +G +G VGP+G
Sbjct: 185  LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG 244

Query: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279
            P GP G  GP G  GA GP+G  G+VG+ G  G  G  GE G PG  G     GP G  G
Sbjct: 245  PAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPV---GPPGNPG 301

Query: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP---PGEPGPAGQDGVGGDKG 1336
              G  G  GAAG PG  G PG  GP+G PGPVG  G  G     GEPGPAG  G  G+KG
Sbjct: 302  ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361

Query: 1337 EDGDPGQPGPPGPSGE------------AGPPGPPGKRGPPGA---AGAEGRQGEKGAKG 1381
            E G  G  GPPGPSGE            AGPPGPPG RG PG+    GA+GR G  G  G
Sbjct: 362  EPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPG 421

Query: 1382 EAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP------GPVGEQGLPGAAGQDGPPGPMG 1435
              GA GP G  GP G  G  G+PG  G RG+P      GP G++G  G  G DG PGP+G
Sbjct: 422  SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481

Query: 1436 P------------PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
            P            PG  G  GDPG  G+KGH GL G  G PG  G  G +G PG QG  G
Sbjct: 482  PAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQG 541

Query: 1484 AKGD---------GGIPGPAGPLGPPGPP---------GLPGPQGPKGNK---------G 1516
             KG+          G+PGP+GP G  G P         GLPGP GP+G +         G
Sbjct: 542  GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAG 601

Query: 1517 STGPAGQKGDSGLPGPPGSPGPPGEV 1542
             TGP G +G SG PGP G+ G PG V
Sbjct: 602  PTGPIGSRGPSGPPGPDGNKGEPGVV 627



 Score =  145 bits (366), Expect = 3e-34
 Identities = 98/279 (35%), Positives = 108/279 (38%), Gaps = 106/279 (37%)

Query: 1368 AGAEGRQGEKGAKGEAGAEGPPGKT------------GPVGPQGPAGKPGPEGL------ 1409
            A  +  Q E   KG AG  GP G+             GP GP GP G PGP GL      
Sbjct: 20   ATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAA 79

Query: 1410 -------------------------------RGIPGPVGEQGLPGAAGQDGPPGPMGPP- 1437
                                           +G  GP GE G PG  G  G  GP GPP 
Sbjct: 80   QYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG 139

Query: 1438 --------------------------GLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471
                                      G PG  G PG KG +GH GL GL G PG  G KG
Sbjct: 140  KAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKG 199

Query: 1472 DRGLPGTQGSPGAKGDGGIP------------------------GPAGPLGPPGPPGLPG 1507
            + G PG  G+PG  G  G+P                        GPAGP+G  GPPG PG
Sbjct: 200  EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259

Query: 1508 PQGPK------GNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
              GPK      GN G  GPAG +G+ GLPG  G  GPPG
Sbjct: 260  APGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPG 298


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 1102 bits (2849), Expect = 0.0
 Identities = 635/1397 (45%), Positives = 739/1397 (52%), Gaps = 125/1397 (8%)

Query: 518  AILQQARIALRGPP---GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG--- 571
            A+  Q   A   PP   GP G  G PGP   PG  G  G+ G PG  G  G  GPPG   
Sbjct: 86   AVCPQPPTAPTRPPNGQGPQGPKGDPGP---PGIPGRNGDPGIPGQPGSPGSPGPPGICE 142

Query: 572  --PTGKP------------------GKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611
              PTG                    G  G PG  G  G PG PG  G  G  G PG  G 
Sbjct: 143  SCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGP 202

Query: 612  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP---RGTPGAPGQPGM 668
             G  G+ GP GPPGPPG  G  G  G+ G  G PG  G RGL GP   +G  G PG PGM
Sbjct: 203  PGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGM 262

Query: 669  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGL--- 725
             G  G  G  G  G  G PG  G+ G PG  G PGP GP G PGE+G  G PG AG    
Sbjct: 263  KGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322

Query: 726  ---------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776
                     PG  GPPG  G  G  G KG +GP G  G  G PG RG  G  G  G +G 
Sbjct: 323  DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382

Query: 777  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK------------GRAGPTGD 824
             G  G +G PG KG+MG  G  G  G +G RG  GP G              G+ G  G+
Sbjct: 383  PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442

Query: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGA---------RGVAGK 875
            PGP G+ GE G  GVPG  G  G+ G  G  G  G PGA GE+GA          G+ G+
Sbjct: 443  PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE 502

Query: 876  PGPRGQRGPTGPRGSRGARGPTGK------------PGPKGTSGGDGPPGPPGER----- 918
             GP G+RG  GP G RGA G  G+            PG  G  G DG PGPPG +     
Sbjct: 503  KGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR 562

Query: 919  -GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 977
             GP GP GP G PG  G PGP G DG PG  G+RG  G  G  GPPG  G  GPQGP G 
Sbjct: 563  PGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGP 622

Query: 978  TGPIGERGHPGPPGPPGEQGLPGAA---GKEGAKGDPGPQGISGKDGPAGLR---GFPGE 1031
            TGP G++G  GPPGP G QGLPG     G+ G  G+PGP+G +G  G  G +   G PGE
Sbjct: 623  TGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682

Query: 1032 RGLPGAQGAPGLKGGEGPQGP---PGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
            RG PG  GAPGL+GG GP GP    G  G PG  G+AGT G  G+PG  G  G PGP G+
Sbjct: 683  RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGD 742

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148
            KG PG  G  G  G+DG +GP G  GP GPAG PG+ G+ G  G PG  G +G  GE G 
Sbjct: 743  KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208
             GPP   GP G PG  G +GEPG +G++G  G+KG+ G  G  GPPG  G  G PGP G 
Sbjct: 803  TGPP---GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
            KGE G  G  G  G PG RG  GP G++G  GPPG  GS    G+ G PG AGN G PG 
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS---PGKDGPPGPAGNTGAPGS 916

Query: 1269 AGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328
             GV GPKG+ G+ GE G PGA GPPGA GP G  G  G  G  G PG PGP G PGP G 
Sbjct: 917  PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 1329 DGVGGDKGEDGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGE---KGAKGE 1382
             G  G  G +G  G+ GPPGP    G AG  G PG+ G PG+ G  GR G    KG +GE
Sbjct: 977  KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGE 1036

Query: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
             G+ G PG  G  GP GP G  G  G RG  GP G  G PG AG  G PGP GP G  G 
Sbjct: 1037 NGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGE 1096

Query: 1443 KGDPGSKGEKGH---PGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1499
             G+ G+ G KGH   PG  G  G PG  G++G  G PG  G  G  G  G PG  G  G 
Sbjct: 1097 TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH 1156

Query: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGP--PGEVIQPLPILSSKKTRRH 1557
            PGP G PGP+G +G +GS G  G  G  G PGPPG+PGP   G     +  +  +K    
Sbjct: 1157 PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEK---- 1212

Query: 1558 TEGMQADADDNILDYSDGMEEIFGSLNSLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDF 1617
              G      D  +D+    +EI  SL S+   IE +  P G++ NPAR C+DL+  HP+ 
Sbjct: 1213 AGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGSRKNPARNCRDLKFCHPEL 1272

Query: 1618 PDGEYWIDPNQGCSGDSFKVYCNFTSGGETCIYPDKKSEGVRISSW----PKEKPGSWFS 1673
              GEYW+DPNQGC  D+ KV+CN  + GETCI  +  +  V    W      EK   WF 
Sbjct: 1273 KSGEYWVDPNQGCKLDAIKVFCNMET-GETCISANPLN--VPRKHWWTDSSAEKKHVWFG 1329

Query: 1674 EFKRGKL-LSYLDVE-GNSINMVQMTFLKLLTASARQNFTYHCHQSAAWYDVSSGSYDKA 1731
            E   G    SY + E    +  VQ+ FL+LL++ A QN TYHC  S A+ D +SG+  KA
Sbjct: 1330 ESMDGGFQFSYGNPELPEDVLDVQLAFLRLLSSRASQNITYHCKNSIAYMDQASGNVKKA 1389

Query: 1732 LRFLGSNDEEMSYD-NNPFIKT-LYDGCASRKG-YEKTVIEINTPKIDQVPIVDVMINDF 1788
            L+ +GSN+ E   + N+ F  T L DGC    G + KTV E  T K  ++PIVD+   D 
Sbjct: 1390 LKLMGSNEGEFKAEGNSKFTYTVLEDGCTKHTGEWSKTVFEYRTRKAVRLPIVDIAPYDI 1449

Query: 1789 GDQNQKFGFEVGPVCFL 1805
            G  +Q+FG +VGPVCFL
Sbjct: 1450 GGPDQEFGVDVGPVCFL 1466



 Score =  934 bits (2415), Expect = 0.0
 Identities = 527/1136 (46%), Positives = 586/1136 (51%), Gaps = 96/1136 (8%)

Query: 443  PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 502
            P  P  P    GP G +G  GPPG PG  G PG PG PG+ G PGPPG     P    G 
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPT---GP 148

Query: 503  GSKGPTISAQEAQAQAIL-----QQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD 557
             +  P   + + ++   +             GPPGP G +G PG  G PG  G  GE G 
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 558  PGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG- 613
             GP GP G  G   P GP GK G+ GRPG  G RG+PG PG KG  G  G PG+ G +G 
Sbjct: 209  AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGF 268

Query: 614  --HRGERGPQGPPGPPGDDGMRGEDGEIGPRG------------LPGEAGPRGLLGPRGT 659
                GE+G  G PG  G++G+ GE+G  GP G            LPG AG RG  G RG+
Sbjct: 269  DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328

Query: 660  ---PGAPGQPGMAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGPQGLPGPQGPIGPPG- 712
               PG PG PG AG  G PG KG +GP G PG    PGQ+G PGPQG  G QGP GPPG 
Sbjct: 329  DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388

Query: 713  --------EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764
                    E GP G PG  GL GA GPPG  G  G  G +G  G PG  G  G PGPRG 
Sbjct: 389  NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 765  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824
            +G  G+ G+ G+KGE G+DG PG  G  GL G  GE G  G RG  GP G  G  GP G+
Sbjct: 449  RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGE 508

Query: 825  ------PGPSGQAGEKGKLGVPGLPGY---PGRQGPKGSTGFPGFPGANGEKGARGVAGK 875
                   GP G AGE G+ GVPG PG    PG  G  GS G PG PG+ GE G  G  G 
Sbjct: 509  RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP--- 932
             GPRGQ G  G  G +G  G  GK G +G  GG GP GPPG+ G  GPQGP G  GP   
Sbjct: 569  SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGD 628

Query: 933  ---KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989
                GPPGP G  GLPG  G  GE G  G+ GP G  G  G  G  G+ G  GERG PG 
Sbjct: 629  KGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688

Query: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL--------------- 1034
             G PG +G  G  G EG KG  GP G  G  G  GL+G PGERG                
Sbjct: 689  AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 1035 PGAQGAPGLKGGEGPQGP---PGPVGSPGERGSAGT------AGPIGLPGRPGPQGPPGP 1085
            PGA G PG  G  GP GP   PGP G PG++G  G       AGP G PG  G  GPPGP
Sbjct: 749  PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 1086 AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1145
            AG  GAPG+ G  G  G  G  G  G  GP G AG P   G  G  G PG +G KG++G 
Sbjct: 809  AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP---GGSGPAGPPGPQGVKGERGS 865

Query: 1146 NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1205
             G PG  G  G  G PG  G +G PGP G  G  G+ G  G  G  G PG  G+ G  G 
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925

Query: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP-- 1263
             G+ GE G  G  GPPG PGP G  G  GA G  GPPG  G  G  G +G  GE+G P  
Sbjct: 926  AGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985

Query: 1264 -------GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316
                   GPPG  G+ G  G  GE G  G PG+ G PG  G PG  G +G  G  G PG 
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045

Query: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1376
            PG PG PGP G  G  GD+GE G  G  G PGP+G  G PGP G RG  G  G  G  G 
Sbjct: 1046 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1436
            KG +G  G  G PG  GP G QG  G PGP G R   GPVG  G PG  G  G PGP+GP
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPR---GPVGPSGPPGKDGTSGHPGPIGP 1162

Query: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE-KGDRGLPGTQGSPGAKGDGGIP 1491
            PG  G +G+ GS+G  GHPG  G  GPPG  G   G  G     G  G K  G  P
Sbjct: 1163 PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAP 1218



 Score =  834 bits (2155), Expect = 0.0
 Identities = 494/1119 (44%), Positives = 553/1119 (49%), Gaps = 170/1119 (15%)

Query: 397  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLV---EGPPGPAGPAGIM 453
            P +   PG P    I E+   G   Y  +    +   V+ G+ V    G PGPAGP G  
Sbjct: 126  PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYD---VKSGVAVGGLAGYPGPAGPPGPP 182

Query: 454  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQE 513
            GPPG  G  G PG PG +GPPG PG  G  G PGPPG +          G  GP  + ++
Sbjct: 183  GPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAI----------GPSGP--AGKD 230

Query: 514  AQAQAILQQARIALRGPP---GPMGLTGRPGPVGG---PGSSGAKGESGDPGPQGPRGV- 566
             ++    +     L GPP   GP G+ G PG  G     G +G KGE+G PG +G  G+ 
Sbjct: 231  GESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLP 290

Query: 567  -----QGPPGPTGKPGKRGRPGA---------DGGR---------------GMPGEPGAK 597
                  GP GP G PG+RGRPG          DG R               G PG PGAK
Sbjct: 291  GENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK 350

Query: 598  GDRGFDGLPGLPGDKGHRGERGP------QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 651
            G+ G  G PG  G  G RGE GP      QGPPGPPG +G  G  GE+GP G+PG  G  
Sbjct: 351  GEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLM 410

Query: 652  GLLGPRGTPGAPGQPGM------------------------AGVDGPPGPKGNMGPQGEP 687
            G  GP G  GA G PG+                        AG+ G PG KG  G  G P
Sbjct: 411  GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470

Query: 688  GPPGQQGNP---------------GPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732
            G PG  G P               GP G+PG +GP G  G  GP G  G AG PG DG P
Sbjct: 471  GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530

Query: 733  GHPGKEGQSGEKGA------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFP 786
            G PG  G  G  G        GPPG QG  G PGP G  G  G  G+ G  G KG DG P
Sbjct: 531  GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 787  GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP------TGDPGPSGQAGEKGKLGVP 840
            G  G+ G  G  G  G  G  GE GP+GP G  GP      TG PGP G  G  G  G P
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 841  GLPGYPGRQGPKGSTGFPGFP------GANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 894
            G  G PG  GPKG  G PG P      GA GE+G  G+AG PG RG  GP GP G +GA 
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAA 710

Query: 895  GPTGKPGPKGT---------SGGDGPPGP---------------PGERGPQGPQGPVGFP 930
            GP G PG  GT          GG G PGP               PG+ GP+GP GP+G P
Sbjct: 711  GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 931  GPKGPPGPPGKDGLPGHP---GQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 987
            GP G PG  G+ G PG P   G RG  G +G+TGPPGP G  G  G  GE G  GERG P
Sbjct: 771  GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 988  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047
            G  G  G  G+ G  G  G  G PGPQG+ G+ G     G PG  G PGA+G PG  G  
Sbjct: 831  GEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP---GGPGAAGFPGARGLPGPPGSN 887

Query: 1048 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA---GEKGAPGEKGPQGP---- 1100
            G  GPPGP GSPG+ G  G AG  G PG PG  GP G A   GEKG+PG +GP G     
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 1101 --AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPV 1158
              AG  G +G  G PG  GP GSPG  G KGE G+PG  G  G++G  GP G PGL G  
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPM 1218
            G PG  G  G  G  G+ G  G KGD G  G PG PG  G  G PGP G  G++GD G  
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067

Query: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278
            GP GP G  GP G  GA GPQGP G  G  G  G  G  G  G PG PG  G  GP G++
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127

Query: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1338
            G  G  GP G  GP G  GPPG DG  G+PGP+         G PGP G  G  G +G  
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI---------GPPGPRGNRGERGSEGSP 1178

Query: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK 1377
            G PGQPGPPGP G  GP       G  GAA   G  GEK
Sbjct: 1179 GHPGQPGPPGPPGAPGP-----CCGGVGAAAIAGIGGEK 1212



 Score =  381 bits (978), Expect = e-105
 Identities = 239/593 (40%), Positives = 271/593 (45%), Gaps = 142/593 (23%)

Query: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141
            P  P GE  A   + P  P      QGP G  G  GP G PG +GD G  G+PG      
Sbjct: 77   PEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS----- 131

Query: 1142 DKGENGP---PGPPGL--------------------------------------QGPVGA 1160
                      PGPPG+                                       GP G 
Sbjct: 132  -------PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP 184

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI------------------GLQGL 1202
            PG +G  G PG  G QG  G+ G  G  G PGPPG I                  G +GL
Sbjct: 185  PGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL 244

Query: 1203 PGPPGEK------------------GENGDVGPMGPPGPPGPRGPQGPNGADGPQGP--- 1241
            PGPPG K                  G NG+ G  G PG  G  G  G NGA GP GP   
Sbjct: 245  PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304

Query: 1242 ---------PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1292
                     PG+ G+ G  G +G  G+ G PGPPG AG  G  G +GE G AG PG+ G 
Sbjct: 305  PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364

Query: 1293 P------------GAKGPPGDDGPKGNP------GPVGFPGDP---GPPGEPGPAGQDGV 1331
            P            GA+GPPG  G  G+P      GP G PG P   G  G PGPAG +G 
Sbjct: 365  PGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGA 424

Query: 1332 GGDKGEDGDP------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385
             G +G  G+P      G+PGP G  GEAG PG PG +G  G  G+ G  G  G  G AG 
Sbjct: 425  PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE 484

Query: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445
             G PG  GP GP G  G+ GP G RG PGP G +G  G  G+DG PG  G  G+PG  G 
Sbjct: 485  RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGG 544

Query: 1446 PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP-------GPAGPLG 1498
            PGS G+ G PG  G  G PG  G  G RG PG  G PG KG+ G P       GP GP G
Sbjct: 545  PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP-G 603

Query: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP------PGSPGPPGEVIQP 1545
            P GPPG  G  GP+G  G TGP G KGD+G PGP      PG+ GPPGE  +P
Sbjct: 604  PQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKP 656



 Score =  156 bits (395), Expect = 2e-37
 Identities = 105/286 (36%), Positives = 116/286 (40%), Gaps = 80/286 (27%)

Query: 1337 EDGDPGQPGPPGPSGEAG---PPGPPGKRGPPGAAGAE------------GRQGEKGAKG 1381
            +D +   P P  P GE     P  P     PP   G +            GR G+ G  G
Sbjct: 68   DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG 127

Query: 1382 EAGAEGPPGK-----------------------------------TGPVGPQGPAGKPGP 1406
            + G+ G PG                                     GP GP GP G PG 
Sbjct: 128  QPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGT 187

Query: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL---IGLIGP 1463
             G  G PG  G QG PG  GQ GP GP GPPG  G  G  G  GE G PG     GL GP
Sbjct: 188  SGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGP 247

Query: 1464 P---------------------GEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGP 1502
            P                     G  GEKG+ G PG +G  G  G+ G PGP GP G PG 
Sbjct: 248  PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE 307

Query: 1503 ---PGLPGPQGPKGNKGSTGPAGQKGDSGLPGP---PGSPGPPGEV 1542
               PGLPG  G +GN G+ G  GQ G  G PG    PGSPG  GEV
Sbjct: 308  RGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  991 bits (2562), Expect = 0.0
 Identities = 597/1300 (45%), Positives = 673/1300 (51%), Gaps = 211/1300 (16%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 480  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 535
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 536  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 585
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 586  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 641
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 690
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 691  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 737
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 738  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 787
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 788  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 834
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 891
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 892  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 930
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 931  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 985  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1042 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1153
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1154 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1205
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1206 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1248
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1249 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1297 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-------- 1345
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG        
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV--------GP 1397
             PG SG+ G  G PG  G PG  G +G  G  G  G  G  GPPG  GP         GP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1398 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL 1457
            QGP G+PGP G +G+PGP G  GLPG  G  G  G  G PGLPGL   PG KG++G PGL
Sbjct: 1257 QGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL---PGLKGDQGPPGL 1313

Query: 1458 IGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP 1511
             G  G PG  G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G 
Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQ 1373

Query: 1512 ----KGNKGSTGPAGQKGDSGLPGP------PGSPGPPGE 1541
                KG+ G  G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1374 SIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413



 Score =  919 bits (2376), Expect = 0.0
 Identities = 577/1313 (43%), Positives = 644/1313 (49%), Gaps = 227/1313 (17%)

Query: 393  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 441
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 442  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 483
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 537
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 538  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 585
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 586  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 636
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 637  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 661
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 662  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 709
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 710  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 761
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 762  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 812
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 864
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 919
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 920  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 976
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 1037 AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1147
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1148 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1258 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1301
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1302 ---DGPKGNPGPVGFPGDPGP------PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
               +GPKGNPGP G PG PGP      PG  GP G  G GG KGE G+PGQPG PG    
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL--- 1301

Query: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI 1412
               PG  G +GPPG  G  GR G  G KG+ G  G PG  G  GP G  G  GPEG  G+
Sbjct: 1302 ---PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 1413 PGPVGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG 1468
             GP G  GLPG +GQ     G  GP G PG PGLKG PG +G +G PG      P G  G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG------PTGPPG 1412

Query: 1469 EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521
            + G  GLPG  G+ G KGD G+PG  G  G  GPPG  G QGP G  G++  A
Sbjct: 1413 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 583
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 584  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 642
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 643  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 702
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 703  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 749
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 750  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 866  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 907
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 908  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 946
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 1002
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 1003 GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1057
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1101
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1102 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1154 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1212 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1271
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1272 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1328
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1329 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1365
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1422
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1470
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1471 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1526 DSGLPGPPGSPGPPGE 1541
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  793 bits (2047), Expect = 0.0
 Identities = 522/1258 (41%), Positives = 602/1258 (47%), Gaps = 192/1258 (15%)

Query: 279  KEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIF 338
            ++ E   +GP      I++ +  I  +FQ+ + G         P  + G   P   E+  
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK-- 285

Query: 339  TEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPN 398
             E+   GE    + K  +D       I G   D    G+ G  D  + ++ +  P  PP 
Sbjct: 286  GEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR-DGEKGQKGDTGPPGPP- 342

Query: 399  EEFGPGVPAE-TDIT---ETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG--I 452
               G  +P   T IT   + +I   G  GEKG++G P +       +GPPG  GP G  +
Sbjct: 343  ---GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI-------QGPPGLPGPPGAAV 392

Query: 453  MGPPGLQGPTGPPGDPGDRGPPG-----RPGL---PGADGLPGPPGTM---------LML 495
            MGPPG  G  G  G  GD GPPG      PGL   PGA GLPGPPG           +  
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 496  PFRYGGDGSKGPTISAQEA-----QAQAILQQARIALRGPPGPMGLTGRPGPVGG---PG 547
            P   G  GS G      E      +           + GPPG  GL G PGP G    PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 548  SSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-------------GGRGMPGEP 594
              G KG++G  GP+G  G+ G PG  G PG +G PG               G  G PG P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 595  GAKGDRGFDGLPGLPGDKGHRGE---RGPQGPPGPPGDDGMRGEDGEIGPRGL--PGEAG 649
            G  G  G DGLPGLPG KG  G    +G +GPPG PG  G+ G  G +GP G   PG  G
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 650  PRGLLGPRGTPGAPG-------------QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNP 696
             +G+ G  G PG PG             QPG  G+ G PG  G++G  G+PG PGQ G P
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 697  GPQG-----------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            G  G           LPGP GP G PG  GP G PG  G  G +GPPG PG  G  GE G
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 746  AL--GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
                GPPGP G  G+ G  G KG  G  G  G  G  G DG PG KGD+G  G  G +G 
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 804  IGPRG--EDGPEGPKGRAGPTGDPGPSGQAGEKG--------------KLGVPGLPGYPG 847
             G  G    GP GP G  GP G PG  G  GEKG              + G PG+PG PG
Sbjct: 813  PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 848  RQGPKGSTGFPG------FPGANGEKGARGVAGKPGP------------------RGQRG 883
              GP GS G PG      FPG  GE G  G  G PGP                  +GQ G
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 884  PTGPRGSRGARGPTGKPGPKG--------TSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
              GP G +G++G  G PGP G        + G  G PG PG  G  GP+G  G PG  G 
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995
            PG  G+ GLPG PG +G  G  G+ G  GP G+ G  G  G  GP G  G PGP G PG+
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055
             G PG  G++G KGDPG   I    G  GL G  GE GLPG  G PG+KG  G  G PG 
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSI----GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG---- 1111
             G+PG +G  G  G  G PG PGP+G  GP G  G PGE GP G  G  G  GP G    
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1112 -----LPGPAGPAGSPGEDG--DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI- 1163
                 +PGPAG  G PG+ G  + G  G PG  G KGD G  G PG PGL GP G PG  
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228

Query: 1164 --AGGDGEPGPRGQQG--MFGQKGDEGARGFPGPPGPIGLQGLPGPPGE---------KG 1210
               G  G PGP G  G  + G KG+ G +G PG PGP G QGLPGP G          KG
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288

Query: 1211 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270
            E G+ G  G PG PG +G QGP G  G  G PG  G  G  G  G PG  G  GP G  G
Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348

Query: 1271 VGGPKGERGE-------------------KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311
              GP+GE G                    KG+AGPPG  G PG KG PG  GP+G PGP 
Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408

Query: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369
            G PGDPG  G P   G DG GG K   GDPG PG PG  G  GPPGP G +GPPG  G
Sbjct: 1409 GPPGDPGRNGLP---GFDGAGGRK---GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 664  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 828
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 829  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 884
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 935
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 936  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 981
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 982  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1039
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1040 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1070
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1131 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1159
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1160 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1204
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1205 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1244
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1287
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1339
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1340 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1397
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1398 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1452
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1453 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1512
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  399 bits (1024), Expect = e-110
 Identities = 259/620 (41%), Positives = 292/620 (47%), Gaps = 117/620 (18%)

Query: 396  PPNEEFGPGVP-AETDITETSING----HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 450
            PP E   PG+P A   I      G     GA G  G KGE  ++ P     GPPGP G  
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGPLGIP 913

Query: 451  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG---- 506
            G  G PGL+G  G  G PG  GP G  G  G  GLPGPPG M   P   G  G KG    
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD--PNLLGSKGEKGEPGL 971

Query: 507  ---PTISAQEAQ-------AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556
               P +S  +          Q  L   +  L GPPGP G  G PG  G  G  G KG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLS-GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 557  DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK--------GDRGFDGLPGL 608
            D G  GP+GV+GPPGP+G PG+ G PG  G +G  G+PG          G +G  GLPG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 609  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            PG+ G +G  G  G PG PG  G +G+ G  G  G PG  GP+G+ GP G PG PG+PG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 669  AG------VDGPPGPKGNMGPQGEPGPPGQQG--------NPGPQGLPGPQGPIGP---- 710
             G        GPPG KG  G  G PGP GQ+G        NPGP GLPG  G  G     
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 711  -----PGEKGPQGKPGLAGLPGADGPPGHPGK-----EGQSGEKGALGPPGPQGPIGY-- 758
                 PG  GP+G+PG  G PG  GPPG PG      EG  G  G  GPPG  GP G+  
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQG 1270

Query: 759  -PGPRGVKGADGVRGLKGSKGEKGEDGFPGF------------------------KGDMG 793
             PGP G  G  G  G+KG KG  G+ G PG                         KGD G
Sbjct: 1271 LPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPG 1330

Query: 794  LKGDRGEVGQIGPRGEDGPEGPKGRAG------PTGDPGPSGQ-------AGEKGKLGVP 840
            L G  G  G  GP G  G  GP+G  G      P G PGPSGQ       AG  G  G P
Sbjct: 1331 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQP 1390

Query: 841  GLPGYPGRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 888
            GL G PG QGP+G              G PGF GA G KG  G+ G+PG RG  GP GP 
Sbjct: 1391 GLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD 1450

Query: 889  GSRGARGPTGKPGPKGTSGG 908
            G    +GP G PG    + G
Sbjct: 1451 G---LQGPPGPPGTSSVAHG 1467



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1416
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1537 GPPGEVIQPLP 1547
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1484 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1528
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1529 LPGPPGSPGPPGEVIQPLP 1547
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  986 bits (2548), Expect = 0.0
 Identities = 593/1291 (45%), Positives = 670/1291 (51%), Gaps = 199/1291 (15%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 480  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 535
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 536  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 585
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 586  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 641
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 690
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 691  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 737
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 738  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 787
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 788  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 834
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 891
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 892  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 930
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 931  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 985  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1042 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1153
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1154 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1205
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1206 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1248
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1249 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1297 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-----PPG 1348
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG     PPG
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGP 1406
              G +G  G  G  G PG  G  G +GE G  G  G +GPPG  G  GP  +GP G PGP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1466
            +G  G PG  G +G PG  G  G  G  G PG PGL G PG KG++G PGL G  G PG 
Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1316

Query: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP----KGNKG 1516
             G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G     KG+ G
Sbjct: 1317 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAG 1376

Query: 1517 STGPAGQKGDSGLPGP------PGSPGPPGE 1541
              G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1377 PPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1407



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 583
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 584  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 642
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 643  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 702
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 703  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 749
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 750  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 866  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 907
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 908  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 946
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 1002
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 1003 GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1057
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1101
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1102 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1154 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1212 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1271
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1272 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1328
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1329 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1365
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1422
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1470
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1471 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1526 DSGLPGPPGSPGPPGE 1541
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  892 bits (2306), Expect = 0.0
 Identities = 559/1291 (43%), Positives = 624/1291 (48%), Gaps = 236/1291 (18%)

Query: 393  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 441
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 442  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 483
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 537
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 538  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 585
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 586  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 636
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 637  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 661
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 662  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 709
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 710  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 761
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 762  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 812
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 864
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 919
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 920  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 976
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 1037 AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1147
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1148 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1258 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1301
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1302 ---DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGP 1358
               +GPKGNPGP G PG PG PG  GP G  G GG KGE G+PGQPG PG  G  G  GP
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1304

Query: 1359 PGKRGPPGAAGAEGRQGE------------KGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
            PG +G PG  G  G +G+            KG  G  G+ GP G+ G +GP GP G PGP
Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGP 1364

Query: 1407 EG-------------------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1447
             G                   L+G+PGP G QGLPG  G  G PG  G PG  G  G  G
Sbjct: 1365 SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKG 1424

Query: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
              G  G PG  GL GPPG  G +G  G PGT
Sbjct: 1425 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score =  787 bits (2033), Expect = 0.0
 Identities = 515/1246 (41%), Positives = 593/1246 (47%), Gaps = 174/1246 (13%)

Query: 279  KEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIF 338
            ++ E   +GP      I++ +  I  +FQ+ + G         P  + G   P   E+  
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK-- 285

Query: 339  TEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPN 398
             E+   GE    + K  +D       I G   D    G+ G  D  + ++ +  P  PP 
Sbjct: 286  GEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR-DGEKGQKGDTGPPGPP- 342

Query: 399  EEFGPGVPAE-TDIT---ETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG--I 452
               G  +P   T IT   + +I   G  GEKG++G P +       +GPPG  GP G  +
Sbjct: 343  ---GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI-------QGPPGLPGPPGAAV 392

Query: 453  MGPPGLQGPTGPPGDPGDRGPPG-----RPGL---PGADGLPGPPGTM---------LML 495
            MGPPG  G  G  G  GD GPPG      PGL   PGA GLPGPPG           +  
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 496  PFRYGGDGSKGPTISAQEA-----QAQAILQQARIALRGPPGPMGLTGRPGPVGG---PG 547
            P   G  GS G      E      +           + GPPG  GL G PGP G    PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 548  SSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-------------GGRGMPGEP 594
              G KG++G  GP+G  G+ G PG  G PG +G PG               G  G PG P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 595  GAKGDRGFDGLPGLPGDKGHRGE---RGPQGPPGPPGDDGMRGEDGEIGPRGL--PGEAG 649
            G  G  G DGLPGLPG KG  G    +G +GPPG PG  G+ G  G +GP G   PG  G
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 650  PRGLLGPRGTPGAPG-------------QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNP 696
             +G+ G  G PG PG             QPG  G+ G PG  G++G  G+PG PGQ G P
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 697  GPQG-----------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            G  G           LPGP GP G PG  GP G PG  G  G +GPPG PG  G  GE G
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 746  AL--GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
                GPPGP G  G+ G  G KG  G  G  G  G  G DG PG KGD+G  G  G +G 
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 804  IGPRG--EDGPEGPKGRAGPTGDPGPSGQAGEKG--------------KLGVPGLPGYPG 847
             G  G    GP GP G  GP G PG  G  GEKG              + G PG+PG PG
Sbjct: 813  PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 848  RQGPKGSTGFPG------FPGANGEKGARGVAGKPGP------------------RGQRG 883
              GP GS G PG      FPG  GE G  G  G PGP                  +GQ G
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 884  PTGPRGSRGARGPTGKPGPKG--------TSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
              GP G +G++G  G PGP G        + G  G PG PG  G  GP+G  G PG  G 
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995
            PG  G+ GLPG PG +G  G  G+ G  GP G+ G  G  G  GP G  G PGP G PG+
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055
             G PG  G++G KGDPG   I    G  GL G  GE GLPG  G PG+KG  G  G PG 
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSI----GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG---- 1111
             G+PG +G  G  G  G PG PGP+G  GP G  G PGE GP G  G  G  GP G    
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1112 -----LPGPAGPAGSPGEDG--DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI- 1163
                 +PGPAG  G PG+ G  + G  G PG  G KGD G  G PG PGL GP G PG  
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228

Query: 1164 --AGGDGEPGPRGQ-----QGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG 1216
               G  G PGP G      +G  G  G +G  G PG PGP G  GLPG  G KGE G+ G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPG 1288

Query: 1217 PMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKG 1276
              G PG PG +G QGP G  G  G PG  G  G  G  G PG  G  GP G  G  GP+G
Sbjct: 1289 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEG 1348

Query: 1277 ERGEKGEAGPPGA-------------AGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323
            E G  G  GPPG              AGPPG  G PG  G  G  GP G PG  GPPG+P
Sbjct: 1349 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP 1408

Query: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369
            G  G  G  G  G  GDPG PG PG  G  GPPGP G +GPPG  G
Sbjct: 1409 GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 664  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 828
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 829  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 884
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 935
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 936  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 981
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 982  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1039
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1040 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1070
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1131 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1159
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1160 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1204
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1205 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1244
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1287
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1339
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1340 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1397
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1398 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1452
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1453 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1512
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  553 bits (1424), Expect = e-157
 Identities = 336/797 (42%), Positives = 389/797 (48%), Gaps = 151/797 (18%)

Query: 403  PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPG----- 457
            PG+P +           G  G  G KGEP +  PG+ + GPPGP G  GI GPPG     
Sbjct: 683  PGLPGQP----------GLPGIPGSKGEPGI--PGIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 458  ----LQGPTGPPGDPGDRG--------PPGRPGLPGADG---------LPGPPGTMLMLP 496
                L+GP GPPG PG +G        PPG PGLPG  G          PGPPG     P
Sbjct: 731  GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP----P 786

Query: 497  FRYGGDGSKGPTISAQEAQAQAILQQAR---IALRGPPGPMGLTGRPGPVGGPGSSGAKG 553
             R G DG  GP            +       I ++GPPGP G+   PGP+G PG  G  G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI---PGPIGQPGLHGIPG 843

Query: 554  ESGDPGP-----------QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE--------- 593
            E GDPGP           +G  G+ G PGP G PG  G PG  G  G PG          
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 594  ---------------PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD-----GMR 633
                           PG KGD G  G PGLPG  G +G +G  G PGPPG       G +
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 634  GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG---PP 690
            GE GE G  G+PG +GP+G  G  G PG PG  G  G+ GPPGPKGN G  G+PG   PP
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 691  GQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP 750
            G +G  G  G PGPQG  GPPG  G  G+PG  GLPG  G  G PG     G  G  GP 
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPK 1082

Query: 751  GPQGPIGYPGPRGVKGA---DGVRGLKGSKGEKGEDGFPGFKG---------------DM 792
            G  G  GYPG  G+KG+    G+ GL G+ G KG+ G PGF G               + 
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 793  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE------------------- 833
            GL G+ G VG  G  G+ GP G KG+ G  G PGP+GQ GE                   
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202

Query: 834  -KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKP--GPRGQRGPTGPRGS 890
             KG  G+PG+PG PG  GPKG  GF GFPG  G  G  G  G    GP+G  GP GP G 
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR 1262

Query: 891  RGARGPTGKPG---------PKGTSGGDGPPGPPGERGPQGP---QGPVGFPGPKGPPGP 938
             G  GP G PG          KG  G  G PG PG +G QGP   QG  G PG  G  G 
Sbjct: 1263 PGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1322

Query: 939  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER-------GHPGPPG 991
            PG  G+PG PG +G +G  G  GP G  G++GP GP G  GP G+        G PG PG
Sbjct: 1323 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1382

Query: 992  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051
             PG +GLPG  G +G  G  GP G  G++G  G  G  G +G PG  G PG +G +GP G
Sbjct: 1383 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1442

Query: 1052 PPGPVGSPGERGSAGTA 1068
            P G  G PG  G++  A
Sbjct: 1443 PDGLQGPPGPPGTSSVA 1459



 Score =  399 bits (1025), Expect = e-110
 Identities = 258/614 (42%), Positives = 291/614 (47%), Gaps = 111/614 (18%)

Query: 396  PPNEEFGPGVP-AETDITETSING----HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 450
            PP E   PG+P A   I      G     GA G  G KGE  ++ P     GPPGP G  
Sbjct: 858  PPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGPLGIP 913

Query: 451  GIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG---- 506
            G  G PGL+G  G  G PG  GP G  G  G  GLPGPPG M   P   G  G KG    
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD--PNLLGSKGEKGEPGL 971

Query: 507  ---PTISAQEAQ-------AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556
               P +S  +          Q  L   +  L GPPGP G  G PG  G  G  G KG  G
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLS-GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 557  DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK--------GDRGFDGLPGL 608
            D G  GP+GV+GPPGP+G PG+ G PG  G +G  G+PG          G +G  GLPG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGY 1090

Query: 609  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            PG+ G +G  G  G PG PG  G +G+ G  G  G PG  GP+G+ GP G PG PG+PG 
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP 1150

Query: 669  AG------VDGPPGPKGNMGPQGEPGPPGQQG--------NPGPQGLPGPQGPIGP---- 710
             G        GPPG KG  G  G PGP GQ+G        NPGP GLPG  G  G     
Sbjct: 1151 VGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 711  -----PGEKGPQGKPGLAGLPGADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRG 763
                 PG  GP+G+PG  G PG  GPPG PG  G +  G KG  GP GP G  G PGP G
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEG 1270

Query: 764  VKGADGVRGLKGSKGEKGEDGFPGF------------------------KGDMGLKGDRG 799
              G  G  G+KG KG  G+ G PG                         KGD GL G  G
Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1330

Query: 800  EVGQIGPRGEDGPEGPKGRAG------PTGDPGPSGQ-------AGEKGKLGVPGLPGYP 846
              G  GP G  G  GP+G  G      P G PGPSGQ       AG  G  G PGL G P
Sbjct: 1331 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1390

Query: 847  GRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 894
            G QGP+G              G PGF GA G KG  G+ G+PG RG  GP GP G    +
Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG---LQ 1447

Query: 895  GPTGKPGPKGTSGG 908
            GP G PG    + G
Sbjct: 1448 GPPGPPGTSSVAHG 1461



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1416
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1537 GPPGEVIQPLP 1547
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1484 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1528
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1529 LPGPPGSPGPPGEVIQPLP 1547
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  984 bits (2545), Expect = 0.0
 Identities = 595/1297 (45%), Positives = 673/1297 (51%), Gaps = 208/1297 (16%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G  G  G KGEP  +    ++   PGP G  G  GPPG+QG  GP G PG  GPPG PGL
Sbjct: 147  GPPGIPGMKGEPGSI----IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 480  ---PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMG- 535
               PG  GLPGP G M  L F+ G  G KG                    L+GPPGP G 
Sbjct: 203  MGPPGPPGLPGPKGNM-GLNFQ-GPKGEKGEQ-----------------GLQGPPGPPGQ 243

Query: 536  LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG----------KPGKRGRPGAD 585
            ++ +  P+      G +G  GD GP GP G++GPPGP G          +PGKRG+PG D
Sbjct: 244  ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 586  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG----PPGDDGMRGEDGEIGP 641
            G  G PG PG  GD G+ G PG  G+KG +G+ GP GPPG     PG     GE G IG 
Sbjct: 304  GENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE-----------PGPP 690
             GLPGE G RG  G +G PG PG PG A V GPPGP G  G +G+           PGPP
Sbjct: 364  PGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 691  GQQGNPGPQGLPGPQGPIGP----------PGEKGPQGKPGLAGLPGADGPPGHPGK--- 737
            G  G PG  GLPGP GP GP          PG  GP G PG  GL G  G  G  G    
Sbjct: 423  GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCF 482

Query: 738  -------EGQSGEKGALGPPGPQGPIGYPGPRGVKG---ADGVRGLKGSKGEKGEDGFPG 787
                    G  G+ G  G PGP G +G+PG +G KG   A G +GL G  G  G  GFPG
Sbjct: 483  NCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542

Query: 788  FKGDMG-------LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG------EK 834
             KG+ G       +KGD+GE+G  G  G  G  G  G+ G  G PGP G+ G      E+
Sbjct: 543  SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGER 602

Query: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR--- 891
            G  G PGLPG PG  GP G  GF G PG  GEKG +GVAG PG  G  GP G  G     
Sbjct: 603  GPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQ 661

Query: 892  ----------GARGPTGKPGPKGTSGGDGPPGPPGERG-----------PQGPQGPVGFP 930
                      G  G  G PG  G  G  G PG PG +G           P GP+G  G P
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 931  GPKGPPGPPGKDGL------PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984
            GP G PG PG+ GL      PG PG +GE GF    GPPGP G+ G +G  G   P G+R
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-ALPGPPGPPGLPGFKGALG---PKGDR 777

Query: 985  GHPGPPGPPGE---QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
            G PGPPGPPG     GLPG  G  G  G PGP G  G  G  G++G PG  G+PG  G P
Sbjct: 778  GFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQP 836

Query: 1042 GLKGGEGPQGPPGPVG-----SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKG 1096
            GL G  G +G PGP G      PGERGS G  G  G  G PG  G PG AG  G PG KG
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 1097 PQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG--- 1153
              G  G  G  GP+G+PG +G  G  G+DG +G+ G PG  G KG KGE G PGPPG   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMD 956

Query: 1154 -----LQGPVGAPGIAGGDGEPGPRGQQGMFG---QKGDEGARGFPGPPGPIGLQGLPGP 1205
                  +G  G PG+ G  G  GP+G QG+ G   Q G  G  G PGPPGP G  GLPG 
Sbjct: 957  PNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQ 1016

Query: 1206 PG---EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPG--------------SVGSV 1248
            PG     G  G +G MG PGP G  GP GP+G  G  G PG              S+G  
Sbjct: 1017 PGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLP 1076

Query: 1249 GGVGEKGEPG------------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
            G  G KGEPG              G+PG PG  G  G KG+ G  G  G PG  GP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 1297 GPPGDDGPKGNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG-----PPG 1348
            GPPG+ G  G PGPVG    PG PGPPGE G  GQDG+ G  G+ G+PGQPG     PPG
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPG 1196

Query: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGP 1406
              G +G  G  G  G PG  G  G +GE G  G  G +GPPG  G  GP  +GP G PGP
Sbjct: 1197 LPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256

Query: 1407 EG------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1460
            +G       +G+PGP G  GLPG  G  G  G  G PGLPGL   PG KG++G PGL G 
Sbjct: 1257 QGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL---PGLKGDQGPPGLQGN 1313

Query: 1461 IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGP------LGPPGPPGLPGPQGP--- 1511
             G PG  G KGD GLPG  G PG KG  G+PG AGP      +GPPGPPGLPGP G    
Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1373

Query: 1512 -KGNKGSTGPAGQKGDSGLPGP------PGSPGPPGE 1541
             KG+ G  G  GQ G  GLPGP      PG  GPPG+
Sbjct: 1374 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1410



 Score =  917 bits (2371), Expect = 0.0
 Identities = 576/1310 (43%), Positives = 644/1310 (49%), Gaps = 224/1310 (17%)

Query: 393  PTSPPNEEFGPGVPAETDIT-ETSINGHGAYGEKGQKG-EPAVVEPGMLVE--------- 441
            P  PP     PG P          +N  G  GEKG++G +     PG + E         
Sbjct: 196  PPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEF 255

Query: 442  --GPPGPAGPAGIMGPPGLQGPTGPPG----------DPGDRGPPGR------PGLPGAD 483
              G  G  G  G  GPPG++GP GPPG          +PG RG PG+      PG+PG  
Sbjct: 256  QKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT------ 537
            G PG PG     P R G  G KG T                    GPPGP GL       
Sbjct: 316  GDPGYPGE----PGRDGEKGQKGDT--------------------GPPGPPGLVIPRPGT 351

Query: 538  ----GRPGPVGGPGSSGAKGESGDPGPQGPRG--------VQGPPGPTGKPGKRGRPGAD 585
                G  G +G PG  G KGE G PG QGP G        V GPPGP G PG+RG+ G +
Sbjct: 352  GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 586  G--GRGMPGEPGAKGDRGFDGLPGLPGDKGHR-------GERGPQGPPGPPGDDGMRGED 636
            G  G  +PG PG  G  G  GLPG PG  G          E GP GPPG PGD G++GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 637  GEIGPRG-------------------LPGEAGPRGLLG---------------PRGTPG- 661
            G  G +G                   LPG  GP G LG               P+G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 662  --APGQPGMAGVDGPPGP----------KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG 709
              APG PG  G  G PG           KG +G  G PG PG  G PG  GLPG  GP G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 710  PPG------EKGPQGKPGLAGLPGADGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGP 761
             PG      E+GP G PGL GLPG  GP G PG    G  GEKG  G  G  G  G PGP
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGP 651

Query: 762  RGVKGADGVR-GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG--------P 812
            +G  G    + G  G  G  G DG  G  GD GL G  G  G  G +GE G        P
Sbjct: 652  KGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGP 711

Query: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQG--------PKGSTGFPGFPGAN 864
             GPKG  G  G PG  G  G  G  G PG PG+PG +G        P G  G PGF GA 
Sbjct: 712  PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771

Query: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG-----GDGPPGPPGERG 919
            G KG RG  G PGP G+ G  G  G +G  GP G+PGP G  G       GPPGPPG  G
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831

Query: 920  PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---PGPGGVVGPQGPTG 976
            P G  G  G PG KG PGPPG D +PG PG+RG  G  G  GP   PG  G+ G  G +G
Sbjct: 832  PIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 977  ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1036
              G  GE G  GPPGPPG  G+PG +G  G KGD G QG  G  GP G +G  GE GLPG
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950

Query: 1037 AQGA--PGLKGGEGPQGPPGPVGSPGE------RGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
              G   P L G +G +G PG  G PG       +G  G  G  GL G+PG  GPPGP G 
Sbjct: 951  PPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG- 1147
             G PG+ G  GP G  G  G +G PGP G  G PG  G  G+ G PG  G KGDKG+ G 
Sbjct: 1011 PGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 1148 ----------PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPI 1197
                      P G PGL G  G PGI G  G+PG  G  G  G KG  G  GFPG PGP 
Sbjct: 1071 SSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPP 1130

Query: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEP 1257
            G +G+ GPPG  G  G+ GP+G  G PG  GP G  G  G  G PG  G      +KGEP
Sbjct: 1131 GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG------QKGEP 1184

Query: 1258 GEAG--NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---------PGAKGPPGD----- 1301
            G+ G  NPGPPG  G+ G KG+ G  G  G PG  GP         PG +GPPG      
Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244

Query: 1302 ---DGPKGNPGPVGFPGDPGPPGEPGPAGQDGV---GGDKGEDGDPGQPGPPGPSGEAGP 1355
               +GPKGNPGP G PG PG  G PGP G  G+   GG KGE G+PGQPG PG       
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGL------ 1298

Query: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415
            PG  G +GPPG  G  GR G  G KG+ G  G PG  G  GP G  G  GPEG  G+ GP
Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGP 1358

Query: 1416 VGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471
             G  GLPG +GQ     G  GP G PG PGLKG PG +G +G PG      P G  G+ G
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG------PTGPPGDPG 1412

Query: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521
              GLPG  G+ G KGD G+PG  G  G  GPPG  G QGP G  G++  A
Sbjct: 1413 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462



 Score =  901 bits (2328), Expect = 0.0
 Identities = 533/1156 (46%), Positives = 599/1156 (51%), Gaps = 181/1156 (15%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPG----- 583
            G  G  GL G PGP G PG  G KG+ G PGP GP+G++GPPG  G PG  G PG     
Sbjct: 54   GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 584  -ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR 642
             A G +G+PG  G KG+RGF G PG PG          QGPPGPPG  GM+GE G I   
Sbjct: 114  GAPGPQGIPGCNGTKGERGFPGSPGFPG---------LQGPPGPPGIPGMKGEPGSIIMS 164

Query: 643  GLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP 702
             LPG         P+G PG PG PG+ G+   PGP G  GP G PGPPG  G PGP GLP
Sbjct: 165  SLPG---------PKGNPGYPGPPGIQGL---PGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 703  GPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-------------HPGKEGQSGEKGALGP 749
            GP+G +G    +GP+G+ G  GL G  GPPG               G +G  G++G  GP
Sbjct: 213  GPKGNMG-LNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 750  PGPQGPIGYP----GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIG 805
            PG +GP G P    G +G +G  G RG  G  GE G+ G PG  GD G  G+ G  G+ G
Sbjct: 272  PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKG 331

Query: 806  PRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANG 865
             +G+ GP GP G   P   PG     GEKG +G+PGLPG  G +G  G  G PG PG  G
Sbjct: 332  QKGDTGPPGPPGLVIPR--PGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG 389

Query: 866  E--KGARGVAGKPGPRGQRGPTGPRGSR--------GARGPTGKPGPKGTSG-------- 907
                G  G  G PG RGQ+G  GP G          G  G  G PGP G +G        
Sbjct: 390  AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449

Query: 908  --GDGPPGPPGERGPQGPQGPVGFPGPK-------------GPPGPPGKDGLP------G 946
                GPPGPPG  G +G QG  G  G K             GPPG PG  GLP      G
Sbjct: 450  ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509

Query: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG----HPGPPGPPGEQGLPGAA 1002
             PGQ+GE G  G TGP G  G+ G  G  G  G  GE G     PG  G  GE G PGA 
Sbjct: 510  FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569

Query: 1003 GKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGAQGAPGLKGGEGPQGPP--GPVG 1057
            G  G  G PG  G+ G  GP G  G   F GERG PG  G PGL G  GP GPP  GP G
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629

Query: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------GEKGAPGEKGPQGPA 1101
              GE+G  G AG  G PG PGP+G PG                  G+ G PG+ G  G  
Sbjct: 630  PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 1102 GRDGVQGP--------VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153
            G  G+ G         +GLPGP GP G PG  G  G  G PG+ G +      GPPGPPG
Sbjct: 690  GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLE------GPPGPPG 743

Query: 1154 LQGPVGAPGIA--GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGE 1211
              GP G PG A  G  G PG  G +G  G KGD G  G PGPPG  GL GLPGP G+ G 
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGP 803

Query: 1212 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1271
            NG  GPMGPPG PG        G  GP GPPG  G +G  G  G PGE G+PGPPG   V
Sbjct: 804  NGQPGPMGPPGLPG-------IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG-LDV 855

Query: 1272 GGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP---AGQ 1328
             GP GERG  G  G PG  GPPG+ G PG  G  G PG  G  G  GPPG PGP    G+
Sbjct: 856  PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915

Query: 1329 DGVGGDKGEDGDPGQPGPPGPSGE---------AGPPGP--------------PGKRGPP 1365
             GV G KG+DG  GQPG PGP+GE          GPPGP              PG  G P
Sbjct: 916  SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975

Query: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIP---GPVGEQGLP 1422
            G +G +G QG  G  G+ G  G PG  GP GP+G  G PG  GL G P   G +G+ G P
Sbjct: 976  GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL--IGLIGPPGEQGEK---------- 1470
            G  G +GPPGP G PG PG  G PG KG+KG PG+  IGL G PG +GE           
Sbjct: 1036 GPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPG 1095

Query: 1471 -----GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG 1525
                 GD GLPG  G+PGAKG  G+PG  G  GPPGP G+ GP G  G  G  GP G  G
Sbjct: 1096 IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155

Query: 1526 DSGLPGPPGSPGPPGE 1541
              G PGPPG  G PG+
Sbjct: 1156 HPGQPGPPGEKGKPGQ 1171



 Score =  786 bits (2029), Expect = 0.0
 Identities = 519/1255 (41%), Positives = 598/1255 (47%), Gaps = 189/1255 (15%)

Query: 279  KEAESVTEGPTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIF 338
            ++ E   +GP      I++ +  I  +FQ+ + G         P  + G   P   E+  
Sbjct: 228  EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK-- 285

Query: 339  TEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPN 398
             E+   GE    + K  +D       I G   D    G+ G  D  + ++ +  P  PP 
Sbjct: 286  GEKGEQGEP-GKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR-DGEKGQKGDTGPPGPP- 342

Query: 399  EEFGPGVPAE-TDIT---ETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG--I 452
               G  +P   T IT   + +I   G  GEKG++G P +       +GPPG  GP G  +
Sbjct: 343  ---GLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGI-------QGPPGLPGPPGAAV 392

Query: 453  MGPPGLQGPTGPPGDPGDRGPPG-----RPGL---PGADGLPGPPGTM---------LML 495
            MGPPG  G  G  G  GD GPPG      PGL   PGA GLPGPPG           +  
Sbjct: 393  MGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICE 452

Query: 496  PFRYGGDGSKGPTISAQEA-----QAQAILQQARIALRGPPGPMGLTGRPGPVGG---PG 547
            P   G  GS G      E      +           + GPPG  GL G PGP G    PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 548  SSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD-------------GGRGMPGEP 594
              G KG++G  GP+G  G+ G PG  G PG +G PG               G  G PG P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 595  GAKGDRGFDGLPGLPGDKGHRGE---RGPQGPPGPPGDDGMRGEDGEIGPRGL--PGEAG 649
            G  G  G DGLPGLPG KG  G    +G +GPPG PG  G+ G  G +GP G   PG  G
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 650  PRGLLGPRGTPGAPG-------------QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNP 696
             +G+ G  G PG PG             QPG  G+ G PG  G++G  G+PG PGQ G P
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 697  GPQG-----------LPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            G  G           LPGP GP G PG  GP G PG  G  G +GPPG PG  G  GE G
Sbjct: 693  GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 746  AL--GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
                GPPGP G  G+ G  G KG  G  G  G  G  G DG PG KGD+G  G  G +G 
Sbjct: 753  FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 804  IGPRG--EDGPEGPKGRAGPTGDPGPSGQAGEKG--------------KLGVPGLPGYPG 847
             G  G    GP GP G  GP G PG  G  GEKG              + G PG+PG PG
Sbjct: 813  PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 848  RQGPKGSTGFPG------FPGANGEKGARGVAGKPGP------------------RGQRG 883
              GP GS G PG      FPG  GE G  G  G PGP                  +GQ G
Sbjct: 873  PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932

Query: 884  PTGPRGSRGARGPTGKPGPKG--------TSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
              GP G +G++G  G PGP G        + G  G PG PG  G  GP+G  G PG  G 
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995
            PG  G+ GLPG PG +G  G  G+ G  GP G+ G  G  G  GP G  G PGP G PG+
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055
             G PG  G++G KGDPG   I    G  GL G  GE GLPG  G PG+KG  G  G PG 
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSI----GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG---- 1111
             G+PG +G  G  G  G PG PGP+G  GP G  G PGE GP G  G  G  GP G    
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGK 1168

Query: 1112 -----LPGPAGPAGSPGEDG--DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI- 1163
                 +PGPAG  G PG+ G  + G  G PG  G KGD G  G PG PGL GP G PG  
Sbjct: 1169 PGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFH 1228

Query: 1164 --------AGGDGEPGP--RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENG 1213
                     G  G PGP   G +G  G +G  G  GF G PGP G  GLPG  G KGE G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG 1288

Query: 1214 DVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGG 1273
            + G  G PG PG +G QGP G  G  G PG  G  G  G  G PG  G  GP G  G  G
Sbjct: 1289 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG 1348

Query: 1274 PKGERGE-------------------KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP 1314
            P+GE G                    KG+AGPPG  G PG KG PG  GP+G PGP G P
Sbjct: 1349 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1408

Query: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAG 1369
            GDPG  G P   G DG GG K   GDPG PG PG  G  GPPGP G +GPPG  G
Sbjct: 1409 GDPGRNGLP---GFDGAGGRK---GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  744 bits (1922), Expect = 0.0
 Identities = 462/1053 (43%), Positives = 524/1053 (49%), Gaps = 188/1053 (17%)

Query: 664  GQPGMAGV--DGPPGPK----GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ 717
            GQP  A       PG K    G  G +GE G PG +G+PG  G PGP+GP GP G+KG  
Sbjct: 21   GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777
            G PG  G  G  GPPG PG  G  G       PG  G  G PGP+G+ G +G +G +G  
Sbjct: 81   GIPGPPGPKGIRGPPGLPGFPGTPGL------PGMPGHDGAPGPQGIPGCNGTKGERGFP 134

Query: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQI------GPRGE---DGPEGPKGRAGPTGDPGPS 828
            G  G  G  G  G  G+ G +GE G I      GP+G     GP G +G  GPTG PGP 
Sbjct: 135  GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 829  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRG----QRGP 884
            G  G  G +G PG PG P   GPKG+ G   F G  GEKG +G+ G PGP G    Q+ P
Sbjct: 195  GPPGPPGLMGPPGPPGLP---GPKGNMGL-NFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPP----GERGPQGPQGPVGFPGPKGP----- 935
                  +G +G  G  GP G  G  GPPGPP    GE+G QG  G  G PG  G      
Sbjct: 251  IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG 310

Query: 936  -PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-------------GPI 981
             PG PG  G PG PG+ GE G +G TGPPGP G+V P+  TG T             G  
Sbjct: 311  IPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 982  GERGHPGPPGPPGEQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG 1039
            GERG PG  GPPG  G PGAA  G  G  G PG +G  G +GP G+   PG  GL G  G
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPG 429

Query: 1040 APGLKGGEGP-------------QGPPGPVGSPGERGSAGT----------------AGP 1070
            APGL G  GP              GPPGP GSPG++G  G                  G 
Sbjct: 430  APGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGI 489

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130
             G PG+PG  G PGP G  G PG+KG +G A   G  GP GLPG  G  G+PG  G KGE
Sbjct: 490  SGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA---GATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 1131 IGE----PGQKGSKGDKGENGPPGPPGL---------------------------QGPVG 1159
             G+    PG KG KG+ G  G PG PGL                           +GP G
Sbjct: 547  PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPG 606

Query: 1160 APGIAG-----------GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG----LQGLPG 1204
             PG+ G           G G PGP G++G+ G  G+ G  G PGP G  G      G PG
Sbjct: 607  NPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1205 PPGEKGENGDVGPMGPPGPPGPRG--------------------PQGPNGADGPQGPPGS 1244
             PG  G +GDVG  G PG PG  G                    P GP G  G  GPPG+
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVG-----------------GPKGERGEKGEAGPP 1287
             G+ G +G +G PG  G PGP GE G                   GPKG+RG  G  GPP
Sbjct: 727  PGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPP 786

Query: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFP--------GDPGPPGEPGPAGQDGVGGDKGEDG 1339
            G  G  G  GP GD GP G PGP+G P        G PGPPG PGP GQ G+ G  GE G
Sbjct: 787  GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKG 846

Query: 1340 DPGQPG--PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1397
            DPG PG   PGP GE G PG PG  GP G  G+ G  G+ GA G  G +G  G  GP GP
Sbjct: 847  DPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906

Query: 1398 QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG--DP---GSKGEK 1452
             GP G PG  G+ G+ G  G QG PG  G  G  G  G PGLPG  G  DP   GSKGEK
Sbjct: 907  PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 1453 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPK 1512
            G PGL G+   PG  G KG +GLPG  G PG  G  G+PGP GP G PG PG PG  GP 
Sbjct: 967  GEPGLPGI---PGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPP 1023

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            G KG+ G  G  G  G+ GPPG  G PG+   P
Sbjct: 1024 GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056



 Score =  401 bits (1030), Expect = e-111
 Identities = 246/565 (43%), Positives = 280/565 (49%), Gaps = 85/565 (15%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452
            PT     +  PG+P      + ++      G KG+KGEP +  PG  + G  GP G  G+
Sbjct: 936  PTGEKGSKGEPGLPGPPGPMDPNL-----LGSKGEKGEPGL--PG--IPGVSGPKGYQGL 986

Query: 453  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 512
             G PG  G +G PG PG  GP G PGLPG  GL GPPG    L    G  G  GP     
Sbjct: 987  PGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG----LKGTIGDMGFPGPQ---- 1038

Query: 513  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD-----PGPQGPRGVQ 567
                          + GPPGP G+ G+PG  G PG  G KG+ G      PG  GP+G  
Sbjct: 1039 -------------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEP 1085

Query: 568  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQG----- 622
            G PG  G PG +G  G  G  G+PG PGAKG  G  G PG PG  G +G  GP G     
Sbjct: 1086 GLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLP 1145

Query: 623  -------------PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGL--LGPRGTPGAPGQPG 667
                          PGPPG+ G  G+DG  GP G  GE G  G    GP G PG  GQ G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205

Query: 668  MAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGPQGLPGP--QGPIGPPGEKGPQGKPGL 722
              G+ G PG  G  GP+GEPG    PG QG PGP G PGP  +GP G PG +GP G+PG 
Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGF 1265

Query: 723  AGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
             GLPG +GPPG PG  G  GEKG  G PG  G  G  G +G  G  G  G  G  G KG+
Sbjct: 1266 QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1325

Query: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-------AGEKG 835
             G PG  G  G+KG  G  G  GP GE G  GP G   P G PGPSGQ       AG  G
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG---PPGLPGPSGQSIIIKGDAGPPG 1382

Query: 836  KLGVPGLPGYPGRQGPKG------------STGFPGFPGANGEKGARGVAGKPGPRGQRG 883
              G PGL G PG QGP+G              G PGF GA G KG  G+ G+PG RG  G
Sbjct: 1383 IPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1442

Query: 884  PTGPRGSRGARGPTGKPGPKGTSGG 908
            P GP G    +GP G PG    + G
Sbjct: 1443 PPGPDG---LQGPPGPPGTSSVAHG 1464



 Score =  158 bits (400), Expect = 4e-38
 Identities = 88/191 (46%), Positives = 97/191 (50%), Gaps = 21/191 (10%)

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG---IPGPV 1416
            G +G  G  G  G +G  G  G  G EGPPG  G  G  G  G PGP+G+RG   +PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476
            G  GLPG  G DG PGP G PG  G KG+ G  G  G PGL G  GPPG  G KG+ G  
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536
                 PG KG+ G PGP G  G PGP G+PGP GP                  PGPPG  
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP------------------PGPPGLM 203

Query: 1537 GPPGEVIQPLP 1547
            GPPG    P P
Sbjct: 204  GPPGPPGLPGP 214



 Score =  146 bits (368), Expect = 2e-34
 Identities = 87/199 (43%), Positives = 100/199 (50%), Gaps = 39/199 (19%)

Query: 1364 PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423
            P       G +GEKG +G  G EG PG  G          PGPEG    PGP G++G  G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPG---------FPGPEGP---PGPRGQKGDDG 81

Query: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483
              G  GP G  GPPGLPG  G PG  G  GH G  G  G PG  G KG+RG PG+ G PG
Sbjct: 82   IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 1484 AKGDGGIPGPAGPLGPPGPPGLPGPQ------------GPKGNKGSTGPAGQK---GDSG 1528
             +G            PPGPPG+PG +            GPKGN G  GP G +   G +G
Sbjct: 142  LQG------------PPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 1529 LPGPPGSPGPPGEVIQPLP 1547
            +PGP G PGPPG +  P P
Sbjct: 190  IPGPIGPPGPPGLMGPPGP 208


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  947 bits (2448), Expect = 0.0
 Identities = 613/1598 (38%), Positives = 758/1598 (47%), Gaps = 226/1598 (14%)

Query: 394  TSP--PNEEFGPGVPAETDITETSINGHGAY--------GEKGQKGEPAVVEPGMLVEG- 442
            TSP  P++    G PA+T +    ++   A         G   +   PA  +P   +   
Sbjct: 303  TSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPRPAAAQPSQKITAT 362

Query: 443  ------PPGPAGPAG----IMGPPGLQG-----------PTGPPGDPGDRGPPGRPGLPG 481
                  P  P+ P+     I  P   Q            PT     P  R  P R   P 
Sbjct: 363  KIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALPTQKQVPPTSRPVPARVSRPA 422

Query: 482  ADGL---PG----PPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQ---ARIALRGPP 531
               +   PG    PP +   LP          PT++  EA+  +   +   AR +   PP
Sbjct: 423  EKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPP 482

Query: 532  GPMGLTGRPGPVGG------PGSSGAKGESGDPGPQGPRGVQGP-PGPTG--KP-----G 577
                L+  P P  G      P ++     SG   P+    V  P   PTG  KP      
Sbjct: 483  PFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEAS 542

Query: 578  KRGRPGADGGRGMPGEPG-AKGDRGFDGLPGLPGDKG----------------------- 613
            K+  P +   + +P  PG A  D     L   P  +                        
Sbjct: 543  KKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSP 602

Query: 614  ----------HRGERGP----QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659
                      H     P     GPPGP GD G+ G  G  G  G+PG  GPRG  GP G 
Sbjct: 603  RPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662

Query: 660  PGAPGQPGMAGVDGPPG---PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716
            PG PG PG  G  G PG    K + G +G+ G PG  GNPGP G  G +G  GP G  G 
Sbjct: 663  PGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGE 722

Query: 717  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776
            QG+PG  G PGA G   +PG++G  G  G  GP G +G IG PG  G+ G+DG RGL G 
Sbjct: 723  QGQPGPEGSPGAKG---YPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGV 779

Query: 777  KGEKGEDGFPGF------KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 830
             G++G+ G PGF      +G  GL G+ GE+G  GP G  G  G  G  GP G PGP G 
Sbjct: 780  PGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGM 839

Query: 831  AG------------EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGP 878
             G            +KG+ GVPG+ G PG QG KGS G PGFPGA G+ G  G  G  G 
Sbjct: 840  KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGS 899

Query: 879  RGQRGPTGPRGSRGARGPTGKPGP---KGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935
             G  GP GP G  G  GP G  GP   KG  G  G PGP G+ GP+G +GP+G PG  G 
Sbjct: 900  IGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGL 959

Query: 936  PGPPGKDGLPGHPGQ---RGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGH------ 986
             G PG+ G PG PG    +GE G  G+ GP G  G +G  G  GE G +GE+G       
Sbjct: 960  EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP 1019

Query: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046
            PG PGP G  G PG  G  G  G+PGPQG  G  GP G+RG  G RG  G  G  G +G 
Sbjct: 1020 PGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGS 1079

Query: 1047 EGPQGPPGPVGSPGERGSAGTAGPIG------LPGRPGPQGPPGPAGEKGAPGEKGPQGP 1100
             G +GPPGP G PG  G  G AG  G       PG PGP GPPG  G  G PG +GPQGP
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 1101 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160
             G  G  GP G PG  G  G PGE G KG++G  G  G +G  G+ G PG  G  GP+G 
Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGP 1199

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE------------ 1208
             G+ G  G+PGP G+    G+KG EG  G  GPPGP G+ G+ GP G+            
Sbjct: 1200 DGLKGDRGDPGPDGEH---GEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256

Query: 1209 ---KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1265
               KG  G +G MG PG PGP G  GP G+ G  GP G+ G +G  GE G  G  G+ G 
Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316

Query: 1266 PGEAGVGGPKGERGEKGEAG-PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD-------- 1316
             G  G  GPKGE+GE+GE G   G  GPPG +GP GD G +G PG  G+PG         
Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376

Query: 1317 ----------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366
                      PGP G PGP G  G  G KG+ G  G PG  G  G  G PGP G  G  G
Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436

Query: 1367 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1426
              G  G  G  G  G+AG +G  G  G  GP GPAGK G  G+ G+P   G QG PG  G
Sbjct: 1437 LEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLP---GAQGPPGFKG 1493

Query: 1427 QDGPPGPMGPP---------GLPGLKGDPGSK------GEKGHPGLIGLIGPPGEQGEKG 1471
            + G PG +GPP         GLPG +G+PGSK      GE G PG+ GL GP G  G+ G
Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG 1553

Query: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1531
             +G+ G +G PG  G  GI GP G LGP G PG  G +G +G+ G  GP G  G  G PG
Sbjct: 1554 FKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPG 1613

Query: 1532 PPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNILD--YSDGMEEIFGSLNSLKQD 1589
            PPG PG P + +Q   + ++ +T   T G       +  D    D   EIF +L+ L   
Sbjct: 1614 PPGPPGGPIQ-LQQDDLGAAFQTWMDTSGALRPESYSYPDRLVLDQGGEIFKTLHYLSNL 1672

Query: 1590 IEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSGGETCI 1649
            I+ +K P+GT+ NPAR C+DL        DG YW+DPN GCS D+ +V CNFT GG+TC+
Sbjct: 1673 IQSIKTPLGTKENPARVCRDLMDCEQKMVDGTYWVDPNLGCSSDTIEVSCNFTHGGQTCL 1732

Query: 1650 YPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTASARQN 1709
             P   S+                 EF              +I+ VQM FL LL++   Q+
Sbjct: 1733 KPITASK----------------VEF--------------AISRVQMNFLHLLSSEVTQH 1762

Query: 1710 FTYHCHQSAAWYDVSSGSYDK-ALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-YEKTV 1767
             T HC     W + +  +  K A+RF   N +          +   DGC  + G + +T+
Sbjct: 1763 ITIHCLNMTVWQEGTGQTPAKQAVRFRAWNGQIFEAGGQFRPEVSMDGCKVQDGRWHQTL 1822

Query: 1768 IEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1805
                T    Q+PI+ V         +++  EVGP CFL
Sbjct: 1823 FTFRTQDPQQLPIISVDNLPPASSGKQYRLEVGPACFL 1860



 Score =  345 bits (884), Expect = 3e-94
 Identities = 216/514 (42%), Positives = 264/514 (51%), Gaps = 59/514 (11%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVE-GPPGPAGPAG 451
            P  PP     PG+P E           G  G+ G  G P   E G++ + G PG  G +G
Sbjct: 1148 PKGPPGAVGEPGLPGEA----------GMKGDLGPLGTPG--EQGLIGQRGEPGLEGDSG 1195

Query: 452  IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG-TMLMLPF-RYGGDGSKGPTI 509
             MGP GL+G  G PG  G+ G  G+ GL G DG PGPPG T +  P  + G  G KG T 
Sbjct: 1196 PMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTG 1255

Query: 510  SAQEAQAQAILQQARI----ALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
            +      Q  L +  +       G PGP G  G  GP G PG  GA+GE G  G  G +G
Sbjct: 1256 AKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKG 1315

Query: 566  VQGPPGPTGKPGKRGRPGADG-GRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 624
            + GP GP G  G++G  G DG   G PG PG +G  G  G  G PGD G+ G+ G QG  
Sbjct: 1316 IVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLR 1375

Query: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG---APGQPGMAGVDGPPGPKGNM 681
            G PG    +G+ G  GPRG PG  G +G  GP+G  G   APG+ G+ G+ G PGP+G +
Sbjct: 1376 GKPGQ---QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVV 1432

Query: 682  GPQ------GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHP 735
            G Q      G  G PG+ G  G QG  G  G  GP G  G +G PG+AGLPGA GPPG  
Sbjct: 1433 GRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGF- 1491

Query: 736  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLK 795
              +G+SG  G LGPPG             +G +G  GL G++GE G  G PG  G+MG  
Sbjct: 1492 --KGESGLPGQLGPPGK------------RGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537

Query: 796  GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 855
               G  G  GP+G  G  G KG  GP G PG  G+ G  G LG+ G  G PG +G KGS 
Sbjct: 1538 ---GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGS- 1593

Query: 856  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 889
                     G+ G +G  G PGPRG+ GP GP G
Sbjct: 1594 --------RGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  107 bits (267), Expect = 1e-22
 Identities = 140/512 (27%), Positives = 174/512 (33%), Gaps = 101/512 (19%)

Query: 1073 LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLP------------GPAGPAG 1120
            LP   GP+G   PA     P    P  P     V GP   P             P  PA 
Sbjct: 282  LPAGRGPRGTVAPATPT-KPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPAS 340

Query: 1121 SPGEDGD-KGEIGEPGQK--GSKGDKGENGPPGPPGLQ-GPVGAPGIAGGDGEPGPRGQQ 1176
              G     +    +P QK   +K  K     P  P     P+ +P        P  +   
Sbjct: 341  VGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSP-------HPTQKTAP 393

Query: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1236
              F +      +  P    P+  +     P EK    + G   PP PP  R P  P  + 
Sbjct: 394  SSFTKSALPTQKQVPPTSRPVPAR--VSRPAEKPIQRNPGMPRPP-PPSTR-PLPPTTSS 449

Query: 1237 GPQGPPGSVGSVGGV-GEKGEPGEAG---NPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1292
              +  P    +   +     +P  A    +  PP  A    P    G      PP    P
Sbjct: 450  SKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVP 509

Query: 1293 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
            P +    G   P+  P  V  PG   P G   P G +                    S +
Sbjct: 510  PTS----GTSTPRTAPA-VPTPGS-APTGSKKPIGSEA-------------------SKK 544

Query: 1353 AGPPGPPGKRGP--PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR 1410
            AGP   P K  P  PG A  +    +   +       P  +T P     PA     + L 
Sbjct: 545  AGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPA-----QFLS 599

Query: 1411 GIPGPVGE-QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1469
              P P      +   AG    P  MGPPG          KG+ G PG  GL G PG  G 
Sbjct: 600  SSPRPTSSGYSIFHLAGSTPFPLLMGPPG---------PKGDCGLPGPPGLPGLPGIPGA 650

Query: 1470 KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---------------------PGP 1508
            +G RG PG  G+PG      +PGP G  G  G PGL                     PGP
Sbjct: 651  RGPRGPPGPYGNPG------LPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGP 704

Query: 1509 QGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
             G KG+KG  GPAG  G+ G PGP GSPG  G
Sbjct: 705  PGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736



 Score = 56.2 bits (134), Expect = 3e-07
 Identities = 52/231 (22%), Positives = 102/231 (44%), Gaps = 21/231 (9%)

Query: 17  FTVTTLALTFLFQAREVRGAAP-VDVLKALDFHNSPEGISKTTGFCTNRKNSKGSDTAYR 75
           F  + + ++F       +GA   VD+L+ L    +  G     G    +       + + 
Sbjct: 23  FLFSWILVSFACHLASTQGAPEDVDILQRLGLSWTKAGSPAPPGVIPFQ-------SGFI 75

Query: 76  VSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEV--GR 133
            +++A+L APT  + P     E  +++ ++   +   +FL ++ ++    Q+G++   G+
Sbjct: 76  FTQRARLQAPTGTVIPAALGTE-LALVLSLCSHRVNHAFLFAVRSQKRKLQLGLQFLPGK 134

Query: 134 SPVFLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRS 193
           + V     H G      + L    ++ DG+WH +A+ +  +TVT++  C ++    L   
Sbjct: 135 TVV-----HLGSRRSVAFDL----DMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPF 185

Query: 194 ER-AIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDC 243
            R   +D  G  +FG        FEG + QF I    + A++YC H    C
Sbjct: 186 HRDPALDPGGSFLFGKMNPHAVQFEGALCQFSIYPVTQVAHNYCTHLRKQC 236


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  936 bits (2418), Expect = 0.0
 Identities = 569/1328 (42%), Positives = 664/1328 (50%), Gaps = 215/1328 (16%)

Query: 422  YGEKGQKGEPAVV----------EPGML-------VEGPPGPAGPAGIMGPPGLQGPTGP 464
            Y  KGQKGEP  +          +PG+         +GPPG A   G  G PG  G  G 
Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGS 1309

Query: 465  PGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKG-PTISAQEAQAQAILQQA 523
            PG  G+ G PG PGL G+ GLPGP G     P   G  G KG P    Q    +      
Sbjct: 1310 PGRAGNPGTPGAPGLKGSPGLPGPRGD----PGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365

Query: 524  RIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD--PGPQGPRGVQGPPGP------TGK 575
            R   +G PGP G  G  GP+G PG  G  G  G    G +G RG +GPPGP       G+
Sbjct: 1366 R---KGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGE 1422

Query: 576  PGKRGRPGADGGRGMPGEPGAKGDRG--FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMR 633
            PG  G PG+ G +G  G PG KG++G   DG PGLPG  G  GE+GP+GPPG  G  G R
Sbjct: 1423 PGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDR 1482

Query: 634  GEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ 693
            G  G +G  G  GE GP G  G RG PG  G+PG  G +GPPGP G  G +GEPG PG  
Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 694  -----------------GNPGPQGLPGPQGPIGP-----PGEKGPQGKP---GLAGLPGA 728
                             G  GP+G  G QG  GP     PG+ GP+G P   G  GL G 
Sbjct: 1543 AVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGR 1602

Query: 729  DGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV---RGLKGSKGEKGEDGF 785
             GPPG  G  G+ G+ G  GPPGP GP G  G  G KG +G     GL G  GE+G  G 
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGA 1662

Query: 786  PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK-LGVPGLPG 844
            PG +G +G KGD+G+ G+ G  G  G  GPKG  G  G PGP G+  + G      G PG
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722

Query: 845  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP-------- 896
              G++GP+G  G PG PGA GE+G  G  G PGP+G  G  GP G +G RGP        
Sbjct: 1723 DRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 897  -TGKP---GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK---DGLPGHPG 949
              GKP   GP G +G  G  G PG  G  G +G  G PGP GPPG PGK   DG PG  G
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 950  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK----- 1004
            + GE G  G+ G  G  G  G  G  G  GP GERG PG  GP G  GLPG  G      
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902

Query: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA------------------------ 1040
             G  G  GP+G  G+ G  G +G PGERGL G  G+                        
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962

Query: 1041 ---------------PGLKGGEGPQGPP---GPVGSPGERGSAGTAGPIGLPGRP----G 1078
                            G KG  G QGPP   GP+G PGERG  G  G  G  G P    G
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALG 2022

Query: 1079 PQGPPGPA---------------------GEKGAPGEKGPQGPAGRDGVQ---GPVGLPG 1114
             +GPPGP+                     GE G PGE+G +G  G  G Q   GP GLPG
Sbjct: 2023 ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPG 2082

Query: 1115 PAGPAGSPGE--------DGDKGEIGEPGQKGSKGDKGENGPPGP------PGLQGPVGA 1160
              GP G PG          G  GE G PG KG+KG+ G NG  GP      PG++G  G 
Sbjct: 2083 TPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220
            PG  G DG PG  G++GM G +G  G +G  GPPGP+G  G PGPPG  G  G  GP GP
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202

Query: 1221 ------PGPPGP--RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVG 1272
                  PG  GP  RG  GP GA G  GPPG  G VG  G  G PG+ G  G PG  G  
Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262

Query: 1273 GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP--VGFPGDPGPPGEPGPAGQDG 1330
            G  G+ G++G  G PG+ G PG  GP G+ GP G PG   VG PG  G  G PG    D 
Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322

Query: 1331 VG--------------GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQ 1374
            VG              G+KGE G  G+PG PG  G+ G PGP G +G PG    G+ G  
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPP 2382

Query: 1375 GEKGAKGEAGAEGPPGKTGPV------GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1428
            G  G KG+ G  G PG  G V      GP+G  G+PGP G RG+ GP G +G+PG  G  
Sbjct: 2383 GPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP 2442

Query: 1429 GPPGPMGPPGLPGLKGD--------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1480
            GPPG +GPPG  GLKGD        PG +GE+G PG+ G  G PG++G +G  G PG++G
Sbjct: 2443 GPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRG 2502

Query: 1481 SPGAKGDGGIPGPAGP-------LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPP 1533
              G KGD G  G  G        LGPPGP G  G  G +G +G  G  G +GD+G PG  
Sbjct: 2503 ERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDK 2562

Query: 1534 GSPGPPGE 1541
            GS G PG+
Sbjct: 2563 GSKGEPGD 2570



 Score =  921 bits (2381), Expect = 0.0
 Identities = 560/1305 (42%), Positives = 643/1305 (49%), Gaps = 221/1305 (16%)

Query: 420  GAYGEKGQKGEPAVVEPGMLV--EGP--------PGPAGPAGIMGPPGLQGPTGPP---- 465
            G  G +G KGEP    PG ++  EGP        PGP+GP G  GP G  GP GPP    
Sbjct: 1338 GERGPRGPKGEPGA--PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 466  -------GDPGDRGP---------PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 509
                   GD G+RGP         PG PGLPG  G PGP G +       G  G KG   
Sbjct: 1396 TAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPV-------GPPGKKGEKG 1448

Query: 510  SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP---QGPRGV 566
             +++               G PG  G  G  GP G PG+ G KG+ G PGP    G +G 
Sbjct: 1449 DSEDGAP------------GLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE 1496

Query: 567  QGPPGPTGK---PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP--------GDKGHR 615
            +GPPGP G    PG  GRPGA G  G PG  G +G++G  G PG P        G KG +
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEK 1556

Query: 616  GERGPQGPPGPPGDDGMRGEDGEI-----GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAG 670
            G+ GP GP G  G  G RG  G +     GP+G PG+ GP GL G  G PG  G PG  G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616

Query: 671  VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP------GPQGPIGPPGEKGPQGKPGLAG 724
              G PGP G +GP+G  G  G++G+ GP G P      G +G  G PG +GP G+ G  G
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG 1676

Query: 725  LPGADGPPGHPGKEGQSGEKGALGPPGPQGPI----------------GYPGPRGVKGAD 768
             PG DG  G PG  G  G++G  GPPGP G +                G  GPRG KG  
Sbjct: 1677 DPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP 1736

Query: 769  GVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS 828
            G+ G  G +G +G  G PG +GD G++G  GE G  GP G DG  G  G+ G  G  GP+
Sbjct: 1737 GLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 829  GQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR 888
            G AG+ G  G  GLPG  G QG  G +G PG PG  GE       GKPG  G+ G  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGED------GKPGLNGKNGEPGDP 1850

Query: 889  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP--PGKDGLPG 946
            G  G +G  G  G  G  G DGP G  G  G  GPQGP G PGP GPPG   PG  G  G
Sbjct: 1851 GEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTG 1910

Query: 947  HPGQRGETGFQGKTGPPGPGGVVGPQG--------------------------------- 973
              G RGETG +G+ G PG  G+ G  G                                 
Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSF 1970

Query: 974  ---PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG----ISGKDGPAGLR 1026
               P    GP G+ G  GPPG  G  G PG  G +G +GDPGPQG      G+ GP G  
Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPS 2030

Query: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPP---GPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083
            G  GE G PG  G PG  GG G  G P   G  G  GERG  G  GP GLPG PGP GPP
Sbjct: 2031 GLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPP 2090

Query: 1084 GP--AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS-- 1139
            GP  + ++  PG  G QGP G  G +G  G  G  GP G  G  G KG+ GEPG +G   
Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150

Query: 1140 ----KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE---------- 1185
                 G++G  GP G PGLQGP G PG  GG G+PGP G  G+ G  G +          
Sbjct: 2151 NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG 2210

Query: 1186 -------------GARGFPGPPGPIGL---QGLPGPPGEKGE---------------NGD 1214
                         GA G PGPPGP GL   QG PG PG+ GE               +GD
Sbjct: 2211 ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGD 2270

Query: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPGS--VGSVGGVGEKGEPGE-----AGNPGPPG 1267
             G  G PG PG  GP GP G  GP G PG   VG  G  GEKG PG       G PG  G
Sbjct: 2271 RGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKG 2330

Query: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGEPGP 1325
            + G+ GP+GE+GE G AG P         G PG+DG KG PGP GF GDP  G PG PGP
Sbjct: 2331 DRGLPGPRGEKGEAGRAGEP---------GDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381

Query: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGA 1385
             G  GV GD G  G PG PG  G  G+ GP G  G+ GP G  G  G  G +G  G  G 
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP 2441

Query: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445
             GPPG  GP G  G  G  G  G+ G+PGP GE+G PG  G+DG PG  GP GL G  G 
Sbjct: 2442 PGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGS 2500

Query: 1446 PGSKGEKGHPGLIGL----------IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG 1495
             G +GEKG  G  GL          +GPPG +G KGD G  G +G  G KG  G  G  G
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG 2560

Query: 1496 PLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
              G  G PG  G  G  G +G  GP GQ G +G+PG PGSPG  G
Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605



 Score =  914 bits (2362), Expect = 0.0
 Identities = 560/1281 (43%), Positives = 647/1281 (50%), Gaps = 191/1281 (14%)

Query: 420  GAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIMGPPGLQGPTGPPG-----DPGDRGP 473
            G  GE G+ G+PAVV P +   +G  G  GPAG  G  G+QG  GPPG     DPG +G 
Sbjct: 1531 GEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGD 1590

Query: 474  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533
            PG  G  G  G  GPPG         G  G KG                      GPPGP
Sbjct: 1591 PGDRGPIGLTGRAGPPGDS-------GPPGEKGDP-----------------GRPGPPGP 1626

Query: 534  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---PTGKPGKRGRPGADGGRGM 590
            +G  GR G VG  G  G  G+ G PG  G RG++G PG   P G+ G +G PG DG  G 
Sbjct: 1627 VGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGS 1686

Query: 591  PGEPGAKGDRGFDGLPGLPG----------DKGHRGERGPQGPPGPPGDDGMRGEDGEIG 640
            PG  G KGDRG  G PG PG          +KG  G+RG +GP GP GD G+ G  GE G
Sbjct: 1687 PGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERG 1746

Query: 641  ---------PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPG 691
                     P+G PG  GP G  G RG PG  G+ G+ G  G  GP G  G  G+ G PG
Sbjct: 1747 IEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG 1806

Query: 692  QQGNPG---PQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG------ 742
            + G PG    QGLPGP GP G PG+ G  GKPGL G  G  G PG  G++G+ G      
Sbjct: 1807 RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASG 1866

Query: 743  ---------EKGALGPPGPQGPIGYPGP-----RGVKGADGVRGLKGSKGEKGEDGFPGF 788
                     E+GA G  GPQGP G PGP     +G  G  G  G KG +GE G  G  G 
Sbjct: 1867 REGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGL 1926

Query: 789  KGDMGLKGDRGEVGQI------------------------------------GPRGEDGP 812
             G+ GL+G+ G V  +                                    GP+G+ G 
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE 1986

Query: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY-------PGRQGPKGSTGFPGFPGANG 865
            +GP G+ GP G PG  G  G++G  G  G PG        PG  G  G  G PG PG  G
Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046

Query: 866  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP--------PGPPGE 917
              G  G AG+PG RG+RG  G RG +G  GP G PG  G  G  GP        PG  GE
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 918  RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG-PG--GVVGP--- 971
            +GP G +G  G PG  G  GP G  G+PG  G RGE G +G+ G PG PG  G+ GP   
Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166

Query: 972  ---QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP-----QGISGKDGPA 1023
               QGP G  GP+G  G PGPPG PG  G  G  G  G KG+PG      +G++G  G  
Sbjct: 2167 PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAV 2226

Query: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG------------SPGERGSAGTAGPI 1071
            GL G PG  GL G QG+PGL G  G  G PG  G            SPG  GS G  GP+
Sbjct: 2227 GLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPV 2286

Query: 1072 GLPGRPGPQGPPGPA--GEKGAPGEKGPQGP-----AGRDGVQGPVGLPGPAGPAGSPGE 1124
            G  G PGP G PG A  G  GA GEKG  G       G  G +G  GLPGP G  G  G 
Sbjct: 2287 GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346

Query: 1125 DGDKGEIGEPGQKGSKGDKGENGPPGP--PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182
             G+ G+ GE GQKG+ G KG  G PG   PG  GP G PG+ G  G PG  G  G+ G  
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFP 2406

Query: 1183 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1242
            G  G RG  G PGP G +GL GPPG +G  G   P+GPPGPPG  GP G +G  G +G P
Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPG---PLGPPGPPGSVGPPGASGLKGDKGDP 2463

Query: 1243 GSVGSVGGVGEKGEPG---EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG-- 1297
            G VG  G  GE+GEPG   E G PG  G  G+ GP G RGE+GE G  G+AG  G KG  
Sbjct: 2464 G-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522

Query: 1298 -----PPGDDGPKGNPG---PVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGP 1349
                 PPG  G KG+ G   P G  GD GP G+ G  G  G    KGE GD G  G PG 
Sbjct: 2523 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG---SKGEPGDKGSAGLPGL 2579

Query: 1350 SGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL 1409
             G  GP G PG  G PG  G+ G+ G  G +GE   +G  G  GP G +G  G  G  GL
Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE---KGDVGFMGPRGLKGERGVKGACGL 2636

Query: 1410 RGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG---EKGHPGLIGLIGPPGE 1466
             G  G  GE G PG  G  G  G MG PG+PG  G PG +G    KG  G  G  GP G+
Sbjct: 2637 DGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGD 2696

Query: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1526
            QGEKG+RG PG  G PG  G+    G AGP GPPG  G  GP+G +G KG  GP G++  
Sbjct: 2697 QGEKGERGTPGIGGFPGPSGN---DGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGER-V 2752

Query: 1527 SGLPGPPGSPGPPGEVIQPLP 1547
             G PG PG+PG  GE  +P P
Sbjct: 2753 VGAPGVPGAPGERGEQGRPGP 2773



 Score =  882 bits (2280), Expect = 0.0
 Identities = 541/1248 (43%), Positives = 627/1248 (50%), Gaps = 256/1248 (20%)

Query: 528  RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587
            +G PG MGL G+ GP   PG  G  G +G PGPQGP G     G  G PG  GRPG+ G 
Sbjct: 1256 KGEPGEMGLRGQVGP---PGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR 1312

Query: 588  RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD------DGMRGEDGEIGP 641
             G PG PGA G +G  GLPG  GD G RG RGP+G PG PG        G+ G  G+ GP
Sbjct: 1313 AGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGP 1372

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP------PGQQGN 695
             G PG  GP G  GPRG PG PG           G KG+ G +G PGP      PG+ G 
Sbjct: 1373 SGPPGPRGPLGDPGPRGPPGLPGT-------AMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425

Query: 696  PGPQGLPGPQGPIGPPGEKGPQGK-----PGLAGLPGADG------PPG---------HP 735
            PG  G PGPQGP+GPPG+KG +G      PGL G PG+ G      PPG          P
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485

Query: 736  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD---- 791
            G  G++GEKG  GPPGP G  G PG  G  GA G  G  G  G +GE G PG  GD    
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 792  ----MGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGY 845
                 G KG++G+VG  GPRG  G +G +G  G    GDPGP G  G++G +G+ G  G 
Sbjct: 1546 GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGP 1605

Query: 846  PGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP------------RGSRGA 893
            PG  GP G  G PG PG  G  G RG  G+ G +G  GP G             RG+ G 
Sbjct: 1606 PGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGV 1665

Query: 894  RGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP--------------------- 932
            RGP G+ G +G  G DG  G PG  GP+G +G  G PGP                     
Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725

Query: 933  -KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991
             +GP GP G  GLPG PG+RG  GF+G   PPGP G  G +GP GE G   +RG PG  G
Sbjct: 1726 QEGPRGPKGDPGLPGAPGERGIEGFRG---PPGPQGDPGVRGPAGEKG---DRGPPGLDG 1779

Query: 992  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051
              G  G PGAAG  G  G  G  G  G+DG  GLRG   E+GLPG  G PGL G  G  G
Sbjct: 1780 RSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG---EQGLPGPSGPPGLPGKPGEDG 1836

Query: 1052 PPG---PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108
             PG     G PG+ G  G  G  G  G  G +G  GP GE+GAPG  GPQGP G  G  G
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 1109 PVG-----LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGD--------------------- 1142
            P G     +PG  GP G  GE G KGE G PG++G +G+                     
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASAL 1956

Query: 1143 ------------------------KGENGPPGPPGLQGPVGAPG---IAGGDGEPGPRGQ 1175
                                    KG++G  GPPG +GP+G PG   + G  G+PGP+G 
Sbjct: 1957 REIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP 2016

Query: 1176 QGM-FGQKGDEGARGFPGPPGPIGLQGLPGP---------PGEKGENGDVG--------- 1216
             G+  G++G  G  G  G PG  G+ GLPG          PGE+GE G+ G         
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076

Query: 1217 PMGPPGPPGPRGPQGPN--------GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
            P G PG PGP GP GP         G  G QGPPG  G+      KGEPG  G+ GP G+
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA------KGEPGSNGDQGPKGD 2130

Query: 1269 AGVGGPKGERGEKGEAGP------PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322
             GV G KG+RGE G  G       PG  G  G +G PG  GP+G PGPVG  GDPGPPG 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 1323 PG------PAGQDGVGGDKGEDGDPGQ-----------PGPPGPSGEAGP---PGPPGKR 1362
            PG      P G  G+ G+ GE G PG+           PGPPGPSG  GP   PG PG+ 
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 1363 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG-------------- 1408
            G  G  GA GR G  G  G+ G+ G PG  G  GP GP G+PGP G              
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 1409 -----------LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG---LKGDPGSKGEKGH 1454
                       L G PG  G++GLPG  G+ G  G  G PG PG    KG PG KG KG 
Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 1455 PGL--IGLIGPPGEQGEKGDRGLPGTQGSPGA---------KGDGGIPGPAGP---LGPP 1500
            PG+   G  GPPG  G KGD GLPG  G+PG          +G+ G PGP+G     GPP
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 1501 GPPGLPGPQGPKGNKGSTGP---AGQKGDSGLPGPPGSPGPPGEVIQP 1545
            G  G+PGP GP G  GS GP   +G KGD G PG  G PGP GE  +P
Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEP 2477



 Score =  860 bits (2223), Expect = 0.0
 Identities = 519/1219 (42%), Positives = 607/1219 (49%), Gaps = 149/1219 (12%)

Query: 394  TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM 453
            + PP E+  PG P             G  GEKG +G P   +PG+     PG AG  G+ 
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPR-GRDGEVGEKGDEGPPG--DPGL-----PGKAGERGLR 1660

Query: 454  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGL---------PGPPGTMLML--------- 495
            G PG++GP G  GD GD G  GR G PG+ G          PGPPG ++           
Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGE 1720

Query: 496  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 555
            P   G +G +GP          A  ++     RGPPGP G  G  GP G  G  G  G  
Sbjct: 1721 PGDRGQEGPRGP--KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD 1778

Query: 556  GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHR 615
            G  G  G  G  GP GP G  GK G PG DG  G+ GE G  G  G  GLPG PG+ G  
Sbjct: 1779 GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKP 1838

Query: 616  GERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMA 669
            G  G  G PG PG+DG +GE G+ G  G  G  GP+G      +LGP+G PG PG  G  
Sbjct: 1839 GLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898

Query: 670  G--VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIG------------------ 709
            G    G PG  G  G +GE G  G+QG PG +GL G  G +                   
Sbjct: 1899 GQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALRE 1958

Query: 710  ---------------PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQG 754
                           P   +GP+G  G  G PG +GP G PG+ G  G++G  GP GP G
Sbjct: 1959 IVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPG 2018

Query: 755  PI----GYPGPRGVKGADG---VRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807
                  G PGP G+ G  G   + GL G  G  GE G PG +G+ G KG+RGE G+ GP 
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078

Query: 808  GEDGPEGPKGRAGP---TGDPGP--SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862
            G  G  GP G  GP     +PGP  SG+ G  G  G  G PG  G QGPKG  G PG  G
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 863  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 922
              GE G RG  G PG  G+RG  GP G  G +GP G PGP G  G  GPPG PG  GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 923  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 982
            PQGP G  G  G  GPPG+       G  G TG  G  GPPGP G+VGPQG  G  G +G
Sbjct: 2199 PQGPSGLKGEPGETGPPGR-------GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVG 2251

Query: 983  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER--GLPGAQGA 1040
            E G PG PG  G  G  G  G  G  G PG  G  G  G  G  G PG+   GLPGA+G 
Sbjct: 2252 ETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGE 2311

Query: 1041 PGLKGG--------EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG-- 1090
             G  GG         G +G  G  G  GE+G AG AG  G PG  G +G PGP G KG  
Sbjct: 2312 KGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDP 2371

Query: 1091 ---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147
                PG  GP GP G  G  G  GLPG  G  G PG+ G +GE+G+PG  G +G  G  G
Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431

Query: 1148 ---------PPGPPGLQGPVGAPGIAGGDGEPG-----PRGQQGMFGQKGDEGARGFPGP 1193
                     PPGPPG  GP GA G+ G  G+PG     PRG++G  G +G++G    PG 
Sbjct: 2432 REGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR---PGQ 2488

Query: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG-------PRGPQGPNGADGPQGPPGSVG 1246
             GP GL G PG  GE+GE GDVG  G  G  G       P GP+G  G  G +GP G  G
Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDG 2548

Query: 1247 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1306
              G  G+ G+PG+ G+ G PG+ G  G  G RG  G  G PGAAG PG  G PG DG  G
Sbjct: 2549 DKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPG 2608

Query: 1307 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366
              G  G  G  GP G  G  G  G  G  GE GD G+ GPPG  G AG  G  G+ G PG
Sbjct: 2609 IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPG 2668

Query: 1367 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1426
             +GA G++G  G KG+ G +G P   GP G QG  G+ G  G+ G PGP G     G+AG
Sbjct: 2669 QSGAPGKEGLIGPKGDRGFDGQP---GPKGDQGEKGERGTPGIGGFPGPSGND---GSAG 2722

Query: 1427 QDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1486
              GPPG +GP G  GL+G  G +            GPPGE+      G PG  G+PG +G
Sbjct: 2723 PPGPPGSVGPRGPEGLQGQKGER------------GPPGERVV----GAPGVPGAPGERG 2766

Query: 1487 DGGIPGPAGPLGPPGPPGL 1505
            + G PGPAGP G  G   L
Sbjct: 2767 EQGRPGPAGPRGEKGEAAL 2785



 Score =  856 bits (2212), Expect = 0.0
 Identities = 537/1275 (42%), Positives = 628/1275 (49%), Gaps = 277/1275 (21%)

Query: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
            GP++    +     L QA    +  P P        PV  P     KG+ G+PG  G RG
Sbjct: 1219 GPSLDQAVSGLATALCQASFTTQPRPEPC-------PVYCP-----KGQKGEPGEMGLRG 1266

Query: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625
              GPPG  G PG+ G PG    +G PG   AKG+RGF G  G PG  G  G       PG
Sbjct: 1267 QVGPPGDPGLPGRTGAPGP---QGPPGSATAKGERGFPGADGRPGSPGRAGN------PG 1317

Query: 626  PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------PGMAG------VDG 673
             PG  G++G  G  GPRG PGE GPRG   P+G PGAPGQ      PG+ G        G
Sbjct: 1318 TPGAPGLKGSPGLPGPRGDPGERGPRG---PKGEPGAPGQVIGGEGPGLPGRKGDPGPSG 1374

Query: 674  PPGP-----------------------KGNMGPQGEPGP------PGQQGNPGPQGLPGP 704
            PPGP                       KG+ G +G PGP      PG+ G PG  G PGP
Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGP 1434

Query: 705  QGPIGPPGEKGPQ-----GKPGLAGLPGAD------GPP---------GHPGKEGQSGEK 744
            QGP+GPPG+KG +     G PGL G PG+       GPP         G PG  G++GEK
Sbjct: 1435 QGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEK 1494

Query: 745  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD--------MGLKG 796
            G  GPPGP G  G PG  G  GA G  G  G  G +GE G PG  GD         G KG
Sbjct: 1495 GERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKG 1554

Query: 797  DRGEVGQIGPRGEDGPEGPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854
            ++G+VG  GPRG  G +G +G  G    GDPGP G  G++G +G+ G  G PG  GP G 
Sbjct: 1555 EKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGE 1614

Query: 855  TGFPGFPGAN------------GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGP 902
             G PG PG              GEKG  G  G PG  G+ G  G RG+ G RGP G+ G 
Sbjct: 1615 KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD 1674

Query: 903  KGTSGGDGPPGPPGERGPQGPQGPVGFPGP----------------------KGPPGPPG 940
            +G  G DG  G PG  GP+G +G  G PGP                      +GP GP G
Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734

Query: 941  KDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPG 1000
              GLPG PG+RG  GF+   GPPGP G  G +GP GE    G+RG PG  G  G  G PG
Sbjct: 1735 DPGLPGAPGERGIEGFR---GPPGPQGDPGVRGPAGEK---GDRGPPGLDGRSGLDGKPG 1788

Query: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP---GPVG 1057
            AAG  G  G  G  G  G+DG  GLR   GE+GLPG  G PGL G  G  G P   G  G
Sbjct: 1789 AAGPSGPNGAAGKAGDPGRDGLPGLR---GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845

Query: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP-----VGL 1112
             PG+ G  G  G  G  G  G +G  GP GE+GAPG  GPQGP G  G  GP      G+
Sbjct: 1846 EPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 1113 PGPAGPAGSPGEDGDKGEIGEPGQKGSKGD------------------------------ 1142
            PG  GP G  GE G KGE G PG++G +G+                              
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 1143 ---------------KGENGPPGPPGLQGPVGAP---GIAGGDGEPGPRGQQGM-FGQKG 1183
                           KG++G  GPPG +GP+G P   G+ G  G+PGP+G  G+  G++G
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 1184 DEGARGFPGPPGPIGLQGLP---------GPPGEKGENGDV---------GPMGPPGPPG 1225
              G  G  G PG  G+ GLP         G PGE+GE G+          GP G PG PG
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 1226 PRGPQGPN--------GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1277
            P GP GP         G  G QGPPG  G+      KGEPG  G+ GP G+ GV G KG+
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGA------KGEPGSNGDQGPKGDRGVPGIKGD 2139

Query: 1278 RGEKGEAGP------PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP------GP 1325
            RGE G  G       PG  G  G +G PG  GP+G PGPVG  GDPGPPG P      GP
Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP 2199

Query: 1326 AGQDGVGGDKGEDGDPGQ-----------PGPPGPSGEAGP---PGPPGKRGPPGAAGAE 1371
             G  G+ G+ GE G PG+           PGPPGPSG  GP   PG PG+ G  G  GA 
Sbjct: 2200 QGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP 2259

Query: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG-----LRGIPGPVGEQGLPGAAG 1426
            GR G  G  G+ G+ G PG  G  GP GP G+PGP G     + G+PG  GE+G PG   
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 1427 QD--GPPGPMGPPGLP---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGL-----P 1476
             D  G PG  G  GLP   G KG+ G  GE G PG  G  G PG +G KGD G+     P
Sbjct: 2320 GDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSP 2379

Query: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQK------GDSGLP 1530
            G  G PG KGD G+PG     G PG  G PG  GP+G  G  GP+G++      G  G+P
Sbjct: 2380 GPPGPPGVKGDLGLPGLP---GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436

Query: 1531 GPPGSPGPPGEVIQP 1545
            GP G PGPPG V  P
Sbjct: 2437 GPLGPPGPPGSVGPP 2451



 Score =  778 bits (2010), Expect = 0.0
 Identities = 465/1082 (42%), Positives = 556/1082 (51%), Gaps = 169/1082 (15%)

Query: 620  PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 679
            P+G  G PG+ G+RG+ G  G  GLPG  G  G  GP G+  A G+ G  G DG PG  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 680  NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG-LPGADGPPGHPGKE 738
              G  G PG PG +G+PG   LPGP+G  G  G +GP+G+PG  G + G +GP    G  
Sbjct: 1312 RAGNPGTPGAPGLKGSPG---LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP----GLP 1364

Query: 739  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 798
            G+ G+ G  GPPGP+GP+G PGPRG  G  G   +KG KG++GE G PG  G+ G+    
Sbjct: 1365 GRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT-AMKGDKGDRGERGPPG-PGEGGIAP-- 1420

Query: 799  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF- 857
            GE G  G  G  GP+GP G  G  G+ G S    E G  G+PG PG PG QGP+G  G  
Sbjct: 1421 GEPGLPGLPGSPGPQGPVGPPGKKGEKGDS----EDGAPGLPGQPGSPGEQGPRGPPGAI 1476

Query: 858  -----PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 912
                  GFPG  GE G +G  G PGP G RG  G  G  GA+GP G PGP G  G  G P
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 913  GPPGER-----------------GPQGPQGPVGFPGPKGPPGP--PGKDGLPGHPGQRGE 953
            G PG+                  GP GP+G  G  G +GPPG   PG  G  G PG RG 
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 954  TGFQGKTGPPG----PG-----GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004
             G  G+ GPPG    PG     G  GP GP G  G  GE G  G  GPPG+ GLPG AG+
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV-------- 1056
             G +G PG +G  G+ G  G  G  G  G PG+ G  G +G  GP GPPG +        
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 1057 --GSPGERGSAGTAGPIGLPGRPGP---------QGPPGPAGE---KGAPGEKGPQGPAG 1102
              G PG+RG  G  GP G PG PG          +GPPGP G+   +G  GEKG +GP G
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776

Query: 1103 ---RDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159
               R G+ G  G  GP+GP G+ G+ GD G  G PG +G +G  G +GPPG PG  G  G
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836

Query: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219
             PG+ G +GEPG  G+ G  G+KGD GA G  G  GP G +G PG  G +G  G  GP+G
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 1220 PPGP--------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE------------------ 1253
            PPG          GP+G +G  G+ G QG PG  G  G  G                   
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASAL 1956

Query: 1254 ---------------------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1292
                                 +G  G++G  GPPG+ G  G  GERG KG+ G PG  GP
Sbjct: 1957 REIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGP 2016

Query: 1293 PGA----KGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
            PG     +GPPG  G  G PG  G PG PG  G  G AG+ G  G++GE G+ G+ G  G
Sbjct: 2017 PGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDG 2076

Query: 1349 PSGEAGPPGPPGKRGP--------PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1400
            P G  G PGPPG  GP        PG +G +G  G KGAKGE      PG  G  GP+G 
Sbjct: 2077 PPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGE------PGSNGDQGPKGD 2130

Query: 1401 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPG---SKGEKGHPGL 1457
             G PG +G RG PGP G+ G PG  G+ G  GP G PGL G +G PG     G+ G PG 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 1458 IGLIGPPGEQGEKGDRGLPGTQGSPG--------AKGDGGIPGPAGPLGPPGPPGLPGPQ 1509
             GL GP G QG  G +G PG  G PG        A G  G PGP+G +GP G PGLPG  
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 1510 GPKGNKGSTG---PAGQKGDSGLPGPPGSP------------GP---PGEVIQPLPILSS 1551
            G  G  G+ G    +G+ GD G PG PGSP            GP   PG+ +  LP    
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 1552 KK 1553
            +K
Sbjct: 2311 EK 2312



 Score =  705 bits (1820), Expect = 0.0
 Identities = 427/959 (44%), Positives = 499/959 (52%), Gaps = 101/959 (10%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP--PGLQGPTGPPGDPGDRGPPGRP 477
            G  G KG++G P ++ P    +GPPG  GP G  G   PG+ G TGP GD G+ G  G  
Sbjct: 1869 GRDGPKGERGAPGILGP----QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 478  GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA------QEAQAQAILQQARIALRGPP 531
            GLPG  GL G PG++  +       G K   +        + + +   + + R   +G  
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 532  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP 591
            G  G  G+ GP+G PG  G KG+ GDPGPQGP G+          G+RG PG  G  G P
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLA--------LGERGPPGPSGLAGEP 2036

Query: 592  GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPR 651
            G+PG         +PGLPG  G  GE G  G  G  G+ G RGE G  GP GLPG  GP 
Sbjct: 2037 GKPG---------IPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 652  GLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 711
            G  GP+ +   PG PG++G  GPPG KG    +GEPG  G QG  G +G+PG +G  G P
Sbjct: 2088 GPPGPKVSVDEPG-PGLSGEQGPPGLKG---AKGEPGSNGDQGPKGDRGVPGIKGDRGEP 2143

Query: 712  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR 771
            G +G  G PGL G  G  GP G PG +G  G  G +G  G  GP G PG  G  G  G  
Sbjct: 2144 GPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPS 2203

Query: 772  GLKGSKGEKGEDG--FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG--- 826
            GLKG  GE G  G    G  G +GL G  G  G +GP+G  G  G  G  G  G PG   
Sbjct: 2204 GLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDG 2263

Query: 827  PSGQAGEKGKLGVPGLPGYPGRQGPKGS---TGFPG-----FPGANGEKGARG-----VA 873
             SG+ G++G  GVPG PG PG  GPKG    TG PG      PGA GEKGA G     + 
Sbjct: 2264 ASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLV 2323

Query: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933
            G+PG +G RG  GPRG +G  G  G+PG  G  G  G PGP G +G  G   P G PGP 
Sbjct: 2324 GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP-GSPGPP 2382

Query: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP---P 990
            GPPG  G  GLPG PG  G  GF G+TGP G  G  GP G  G  GP G  G PGP   P
Sbjct: 2383 GPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPP 2442

Query: 991  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1050
            GPPG  G PGA+G +G KGDPG           GL G  GERG PG +G  G  G EGP+
Sbjct: 2443 GPPGSVGPPGASGLKGDKGDPG----------VGLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQ----GPPGPAGEKGAPGEKGPQGPAGRDGV 1106
            G  GP GS GERG  G  G  GL G  G      GPPGP G KG  GE+GP+G    DG 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG---LDGD 2549

Query: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGAPGI 1163
            +GP G  G  G  GS GE GDKG  G PG +G  G +G+ G    PG PG  G  G PGI
Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609

Query: 1164 AGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG---EKGENGDVGPMGP 1220
             G  G+ G  G +G+ G++G +GA G  G  G  G  G PG PG    KGE G+ G  G 
Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669

Query: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG------------EAGNPGPPGE 1268
             G PG  G  GP G  G  G PG  G  G  GE+G PG             AG PGPPG 
Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS 2729

Query: 1269 AGVGGPKGERGEKGEAGPPG-----AAGPPGA------KGPPGDDGPKGNPGPVGFPGD 1316
             G  GP+G +G+KGE GPPG     A G PGA      +G PG  GP+G  G      D
Sbjct: 2730 VGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  512 bits (1319), Expect = e-144
 Identities = 307/694 (44%), Positives = 356/694 (51%), Gaps = 106/694 (15%)

Query: 963  PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGP 1022
            P P  V  P+G  GE G +G RG  GPPG PG  G  GA G +G  G    +G  G  G 
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA 1303

Query: 1023 AGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP-GPQG 1081
             G  G PG  G PG  GAPGLKG  G    PGP G PGERG  G  G  G PG+  G +G
Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGL---PGPRGDPGERGPRGPKGEPGAPGQVIGGEG 1360

Query: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGE--DGDKGEIGEPGQKG- 1138
            P       G PG KG  GP+G  G +GP+G PGP GP G PG    GDKG+ GE G  G 
Sbjct: 1361 P-------GLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP 1413

Query: 1139 -----SKGDKGENGPPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFP 1191
                 + G+ G  G PG PG QGPVG PG  G  GD E G  G  G  G  G++G RG P
Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251
            G  GP G +G PGP GE GE G+ GP GP G  G  G  G  GA GP+GPPG  G  G  
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG-- 1531

Query: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG-----DDGPKG 1306
             EKGEPG  G+P   G A V GPKGE+G+ G AGP GA G  G +GPPG     D GPKG
Sbjct: 1532 -EKGEPGRPGDPAVVGPA-VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589

Query: 1307 NPG---PVGF------------------PGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345
            +PG   P+G                   PG PGPPG  GP G+DG  G+KG++G PG PG
Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649

Query: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK-- 1403
             PG +GE G  G PG RGP G  G +G  GE G  G  G+ GP G  G  GP GP G+  
Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLV 1709

Query: 1404 -----------PGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKGDPGSK 1449
                       PG  G  G  GP G+ GLPGA G+   +G  GP GP G PG++G  G K
Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEK 1769

Query: 1450 GEKGHPGLIG---------LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP 1500
            G++G PGL G           GP G  G  G  G PG  G PG +G+ G+PGP+GP G P
Sbjct: 1770 GDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLP 1829

Query: 1501 GPPG------LPGPQGPKGNKGSTGPAGQKGDSGL------------------------P 1530
            G PG      L G  G  G+ G  G  G+KGDSG                         P
Sbjct: 1830 GKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPP 1889

Query: 1531 GPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQAD 1564
            G PG  GPPG+    +P  +  K  R   G + +
Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGE 1923



 Score =  128 bits (322), Expect = 4e-29
 Identities = 80/194 (41%), Positives = 92/194 (47%), Gaps = 22/194 (11%)

Query: 1397 PQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1456
            P+G  G+PG  GLRG  GP G+ GLPG   + G PGP GPPG         +KGE+G PG
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPG---RTGAPGPQGPPG------SATAKGERGFPG 1302

Query: 1457 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516
              G  G PG  G  G  G PG +GSPG  G  G PG  GP GP G PG PG        G
Sbjct: 1303 ADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV-----IG 1357

Query: 1517 STGPA--GQKGDSGLPGPP------GSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDN 1568
              GP   G+KGD G  GPP      G PGP G    P   +   K  R   G     +  
Sbjct: 1358 GEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417

Query: 1569 ILDYSDGMEEIFGS 1582
            I     G+  + GS
Sbjct: 1418 IAPGEPGLPGLPGS 1431


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  920 bits (2378), Expect = 0.0
 Identities = 584/1379 (42%), Positives = 674/1379 (48%), Gaps = 281/1379 (20%)

Query: 419  HGAYGEKGQKGEPAVVE----PGML----VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGD 470
            HG  G+KG++G P +      PGM      +GPPG  G  G  G PG +G  GPPG  G 
Sbjct: 42   HGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGY 101

Query: 471  RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGP 530
             G PG PG+PG DG PGPPG    +P   G  G +GP                     GP
Sbjct: 102  PGNPGLPGIPGQDGPPGPPG----IPGCNGTKGERGPL--------------------GP 137

Query: 531  PGPMGLTGRPGPVGGPGSSGAKGE-------------------SGDPGPQGPRGVQGPPG 571
            PG  G  G PGP G PG  G  GE                    G PGP G  G+QGP G
Sbjct: 138  PGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVG 197

Query: 572  P---TGKPGKRGRPGADGGRGM-----PGEPGAKGDRGFDGLPGLPG-----DKGHRGER 618
            P   TG PG  G PG  G +G       G  G KGD+G  G PG+PG     +KG    +
Sbjct: 198  PPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATK 257

Query: 619  GPQGPPGPPGDDGM-----RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 673
            G +G  G PG  GM     +GE G+ GPRG PG+ G +G  G  G PG PG PG+ G  G
Sbjct: 258  GEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQG 317

Query: 674  PPGPKGNMGPQGEPG------PPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP- 726
            P G KG  GP G PG      P G++G  G  G PGP+G  GP G  G  G+PG  GLP 
Sbjct: 318  PQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPV 377

Query: 727  -GADGPPGHPGKEGQSGEKGALGP--PGPQGPIGYPGPRGVKGADGVRGLK--------- 774
             G  G PG PG+ G+ G++G  G   PGP G  G PGP G  G  G  G           
Sbjct: 378  PGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPG 437

Query: 775  --GSKGEKGEDGFPGFKGDMGLKGDRGEVGQI----GPRGEDGPEGPKGRAGPTGDPGPS 828
              G +G  G  G PGF G++G KG +GE   I    G RG  GP+GP G  G  G PG  
Sbjct: 438  PPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAK 497

Query: 829  GQ---------AGEKGKLGVPGLPGYPGRQGP-------------KGSTGFPGFPGANGE 866
            G          AG  G  G PGL G PG +G              KG  GFPG PG  G 
Sbjct: 498  GDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGR 557

Query: 867  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG--ERGPQGPQ 924
             G+ G  G PG  G +G  G  G +G RGP G  G  G+ G  GPPGPPG    GP G +
Sbjct: 558  AGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDK 617

Query: 925  GPVGFPG---------PKGPPG-------PPGKDGLPGHPG---QRGETGFQGKTGPPG- 964
            G  GFPG         PKG PG       PPG +GLPG PG    +G+ GF G  G PG 
Sbjct: 618  GQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGL 677

Query: 965  ---------PG-GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP- 1013
                     PG G  GP GP G  G  G+ G PG PG PG  GLPG  G +G KG+PG  
Sbjct: 678  PGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVG 737

Query: 1014 -QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPPGPVGSPGERGSAG 1066
              G+ G  G  G+ G PGE+G  G  G PG  G  GP      +G PGP G PG  GS G
Sbjct: 738  LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG 797

Query: 1067 TAG--PIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD-----GVQGPVGLPGPAGPA 1119
              G  P G  G PG QGPPG +G  G  GEKG  G  G D     G +G  GLPG  G +
Sbjct: 798  VPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQS 857

Query: 1120 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--GD----GEPGPR 1173
            G PG  G +G  G PG  GSKG+ G  G PG PG  GPVGAPG+ G  GD    G  GPR
Sbjct: 858  GLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPR 917

Query: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP------------- 1220
            G  G+ G KGD G  G PG    + +  + G  G++GE G +GP+G              
Sbjct: 918  GDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVP 977

Query: 1221 --------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG---PPGEA 1269
                    PG PGP+G  G +G  G  G PG  GSVGG+G  G PGE G PG   P G  
Sbjct: 978  GKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSP 1037

Query: 1270 GVGGPKGERGEKGEAGPPGAA-----------------GPPGAKGP---------PGDDG 1303
            G+ G KG +GEKG+AGPPG                   G PG KG          PG  G
Sbjct: 1038 GLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPG 1097

Query: 1304 PKGNPGPVGFPGDPGPPGEPGP---AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360
             KG+PG VG+PG PG PGE G     G DG+ G KGE G PG PGP GP+G+ G PG  G
Sbjct: 1098 LKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG 1157

Query: 1361 --------------KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
                           RG PG  GA+G +G KG  G  G  G PG  G  G QG  G PGP
Sbjct: 1158 IPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGP 1217

Query: 1407 EGLRGIP--------GPVGEQGLPGAAGQDGPPGPMGPPGLPGL---KGD---------P 1446
            +G  G+P        GP G++G  G  G  G PGPMGPPGLPG+   KGD         P
Sbjct: 1218 QGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAP 1277

Query: 1447 GSKGEKGHPGLIGL---------------IGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP 1491
            G  G KG PG  G+               +GPPG  G +G +GLPG QG  G +GD G+P
Sbjct: 1278 GVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP 1337

Query: 1492 GPAGPLGPPGP----------PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
            G  G  GPPGP          PGLPGP+GP G KG  G  G KG  G+ G  G PGPPG
Sbjct: 1338 GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396



 Score =  915 bits (2366), Expect = 0.0
 Identities = 582/1390 (41%), Positives = 670/1390 (48%), Gaps = 260/1390 (18%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452
            P  PP ++   G P     T+ +    GA G  G  G P +  PG   +GPPGP G  G 
Sbjct: 71   PQGPPGQKGDTGEPGLPG-TKGTRGPPGASGYPGNPGLPGI--PGQ--DGPPGPPGIPGC 125

Query: 453  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFRYGG-DGSKG 506
             G  G +GP GPPG PG  G PG PGLPG  G PG      PG +L     + G  G+ G
Sbjct: 126  NGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPG 185

Query: 507  PTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG--DPGPQGPR 564
            P                   L+GP GP G TG PGP G PG  G KG+ G    GP+G +
Sbjct: 186  PP--------------GLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDK 231

Query: 565  GVQGPPGPTGKPGK-------------------------------RGRPGADGGRGMPGE 593
            G QG  GP G PG+                               +G PG  G RG PG+
Sbjct: 232  GDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGK 291

Query: 594  PGAKGDRGFDGLPGLPGDKGHRGERGPQG------PPGPPGDDGMRGEDGEIGPRGLPGE 647
             G KG++G  G PG PG  G  G +GPQG      PPGPPG     G  GE G RG PG 
Sbjct: 292  DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGT 351

Query: 648  AGPRGLLGPRGTPGAPGQPG--------MAGVDGPPGPKGNMGPQGEPG-----PPGQQG 694
             GPRG  GP+G PG PGQPG         AG  G PG +G  G +G PG     P G+ G
Sbjct: 352  PGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDG 411

Query: 695  NPGPQGLPGPQGPIG-----------PPGEKGPQGKPGLAGL------------------ 725
             PGP G PGP G  G           PPG++GP G PG  G                   
Sbjct: 412  LPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICD 471

Query: 726  -------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS-- 776
                   PG  GPPG  G  GQ G KG  G PG  G  G PGP+G  G  G  G KG   
Sbjct: 472  IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531

Query: 777  --------KGEKGEDGFPGFKG------------DMGLKGDRGEVGQIGPRGEDGPEG-- 814
                    KG+KG+ GFPG  G              GL G +G  G +G +GE GP G  
Sbjct: 532  EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591

Query: 815  ----PKGRAGPTGDPG--PSGQAGEKGKLGVPGLPGYPGRQGPKGSTG------------ 856
                 +G  GP G PG  P+G  G+KG+ G PG PG PG  GPKG  G            
Sbjct: 592  GFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAE 651

Query: 857  ----FPGFPGANGEKGARGVAGKPGPRGQRG-----------PTGPRGSRGARGPTGKPG 901
                 PGFPG  G++G  G  G+PG  G++G           P GP+G  G  G  G PG
Sbjct: 652  GLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPG 711

Query: 902  PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK-- 959
              G  G +G PG PG +G +G  G VG PG KG PG PG  G PG  G  G  G  G+  
Sbjct: 712  TPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHG 770

Query: 960  -TGPPGPGGVVGPQGPTGETGPIGERGHPG--PPG---PPGEQGLPGAAGKEGAKGDPGP 1013
              GPPG  G+ G  GP G  G +G  G PG  PPG   PPG QG PG +G  G KG+ G 
Sbjct: 771  AIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830

Query: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073
             G  G D P G +G  G +GLPG  G  GL G  G QG PG  G PG +G  G  G  G 
Sbjct: 831  PGFPGLDMP-GPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQ 889

Query: 1074 PGRPGPQGPPGPAGEKGA---PGEKGPQGPAGRDGVQGPVGLPGPAGPA---------GS 1121
            PG PGP G PG  GEKG    PG  GP+G  G  G +G VGLPG  G           G 
Sbjct: 890  PGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQ 949

Query: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGP------PGLQGPVGAPGIAGGDGEPG---P 1172
             G+ G+KG+IG  G+KGS+GD G  G PG       PG  GP G PGI+G  G PG   P
Sbjct: 950  KGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGP 1009

Query: 1173 RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP 1232
            +G  G  G  G  G +G PG PGP G  GLPG  G KGE G  GP G  G PG RG +G 
Sbjct: 1010 KGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPGLRGEKGD 1068

Query: 1233 NGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP 1292
             G  G  G PG  G  G +G  G PG  G  G PG  G  G  G  GEKG+ G PG  G 
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 1293 PGAKG---------PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQD-----GVGGDKGED 1338
            PG KG         P G  G KG PG  G PG  G  GEPG  G+      G  GDKG  
Sbjct: 1129 PGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSK 1188

Query: 1339 GD------PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1392
            G+       G PG PG  GE G  GPPG +G PG  G+ G   E G KG+ G +G PG  
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATE-GPKGDRGPQGQPGLP 1247

Query: 1393 GPVGPQGPAGKPGPEGLRG------------IPGPVGE---QGLPGAAGQDG-------- 1429
            G  GP GP G PG +G++G            +PGP G+   QG+PG  G  G        
Sbjct: 1248 GLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDM 1307

Query: 1430 ----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE----KGDRGLPGTQGS 1481
                 PG  GP GLPGL+G  G +G++G PG  GL GPPG  G     KG+ GLPG +G 
Sbjct: 1308 GPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367

Query: 1482 PGAKGDGGIPGPAGP------LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1535
            PG KG  G+PGP G       +G PGPPG+PG  G  G KG  GPAG  G  G PGPPG 
Sbjct: 1368 PGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGP 1427

Query: 1536 PGPPGEVIQP 1545
             G PG +  P
Sbjct: 1428 DGLPGSMGPP 1437



 Score =  895 bits (2312), Expect = 0.0
 Identities = 550/1240 (44%), Positives = 643/1240 (51%), Gaps = 161/1240 (12%)

Query: 403  PGVPAETDITETSINGHGAYGEKGQKGEPAVVE-PGMLVEGPPGPAGPAGIMGPPGLQGP 461
            PGVP +  + E         GEKGQKGEP     PG+  +G PG  GP G  G  G +G 
Sbjct: 240  PGVPGQAQVQEKG--DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297

Query: 462  TGPPGDPGDRGPPGRPGLPGADGL------PGPPGTMLML-PFRYGGD----GSKGPTIS 510
             G PG PG+ G PG  G  G  G       PGPPG ++   P    G+    G+ GP   
Sbjct: 298  KGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGP--- 354

Query: 511  AQEAQAQAILQQARIALRGPPGPMG---LTGRPGPVG--GPGSSGAKGESGDPGPQGPRG 565
                             RG PGP G   L G+PGP G   PG +GA G  G+ G +G RG
Sbjct: 355  -----------------RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRG 397

Query: 566  VQGP--PGPTGKPGKRGRPGADGGRGMPG--------EPGAKGDRGFDGLPGLPG----- 610
              G   PGP+G+ G  G PG+ G  G PG        +PG  GD+G  G+PG PG     
Sbjct: 398  FPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEI 457

Query: 611  -DKGHRGE----------RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659
             +KG +GE          RGP GP GPPG+ G  G+ G  G RGLPG  G  G+ GP+GT
Sbjct: 458  GEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGT 517

Query: 660  PGAPGQPGMAGVDGP-------PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 712
            PG  GQPG  G  G         G KG+ G  G+PG  G+ G+PG  G PG  GP G PG
Sbjct: 518  PGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPG 577

Query: 713  E---KGPQGKPGLAGLPGA---DGPPGHPG--KEGQSGEKGALGPPGPQGPIGYPGPRGV 764
                KG +G PG  G PG+    GPPG PG    G  G+KG  G PG  G  G PGP+G 
Sbjct: 578  SVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGE 637

Query: 765  KG----------ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 814
             G          A+G+ G  G  G +G+ GFPG  G  GL G++G VGQ G  G  GP G
Sbjct: 638  PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPG 696

Query: 815  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGP--------KGSTGFPGFPGANGE 866
            PKG  G  GD GP G  G  G  G+PG PG  G++G         KG  G PG PG  GE
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 867  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG--GDGPPG---PPGERGPQ 921
            KG+ GV G PG  G  GP G +G RG  GP G PG  G+ G  G GPPG   PPG +GP 
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 922  GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPI 981
            G  GP G  G KG PG PG D +PG  G +G  G  G TG  G  G+ G QG  G  G  
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFP 875

Query: 982  GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
            G +G  G  G PG+ G PG  G  G  G+ G  G  G  GP G  G  G++G  G  G P
Sbjct: 876  GSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKP 935

Query: 1042 G---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092
            G         +KG +G QG  G +G  GE+GS G  G  G+PG+ G  G PG  G KG P
Sbjct: 936  GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP 995

Query: 1093 GEKGPQGPAGRDGVQGPVG---LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149
            G  G  G  G  G +G VG   LPG  G  G PG  G +G  G PG KG+KG+KG+ GPP
Sbjct: 996  GISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPP 1055

Query: 1150 GP--PGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207
            G   PGL+G  G  GIAG  G PG +G++G  G  G  G+ G  G PG +G  G PG PG
Sbjct: 1056 GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG 1115

Query: 1208 EKGENGDVGPMGPPGPPGPRG---PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN-- 1262
            EKG+ G  G  G PG  G  G     GP G  G +G PGS G  G  GEKGEPG  G   
Sbjct: 1116 EKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGF 1175

Query: 1263 PGPPGEAGVGGPKGE---------------RGEKGEAGPPGAAGPPGAKGPPGD--DGPK 1305
            PG PG  G  G KGE               +GE+G  GPPG  G PG  G PG   +GPK
Sbjct: 1176 PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPK 1235

Query: 1306 GNPGPVG---FPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKR 1362
            G+ GP G    PG PGP G PG  G DGV GDKG  G PG PG PGP G+ G  G PG  
Sbjct: 1236 GDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIG 1295

Query: 1363 GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1422
            G PG  G++G  G  G  G  G +G PG  G  G QG  G PG +GL G PGP G   + 
Sbjct: 1296 GSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDI- 1354

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482
               G+ G PGP GPPGL GL+G PG KG++G  GL+G+ GPP         G+PG  G+P
Sbjct: 1355 -IKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPP---------GIPGFDGAP 1404

Query: 1483 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG 1522
            G KG+       GP GP GP G PGP GP G  GS GP G
Sbjct: 1405 GQKGE------MGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438



 Score =  816 bits (2107), Expect = 0.0
 Identities = 502/1140 (44%), Positives = 582/1140 (51%), Gaps = 161/1140 (14%)

Query: 538  GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597
            G  G  G  G  G +G  G PG QGP G QGPPG  G  G+ G PG  G RG    PGA 
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG---PPGAS 99

Query: 598  GDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD------DGMRGEDGEIGPRGLPGEA--- 648
            G  G  GLPG+PG  G            PPG       +G +GE G +GP GLPG A   
Sbjct: 100  GYPGNPGLPGIPGQDG------------PPGPPGIPGCNGTKGERGPLGPPGLPGFAGNP 147

Query: 649  GPRGLLGPRGTPG----------APGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGP 698
            GP GL G +G PG            G+ G  G+ G PGP G  G QG  GPPG  G PGP
Sbjct: 148  GPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGP 207

Query: 699  QGLPGPQGP--------IGPPGEKGPQGKPGLAGLPG-----ADGPPGHPGKEGQSGEKG 745
             G PGP G          GP G+KG QG  G  G+PG       G     G++GQ GE G
Sbjct: 208  PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267

Query: 746  ALGPP--GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
              G P  G +G  G PGPRG  G DG +G KGS G  GE G+PG  G  G +G++GE G 
Sbjct: 268  FQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 804  IGPRG---EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGF 860
             GP G     GP G KG  G  G PGP G+ G KG  G+PG PG PG   P G  G PGF
Sbjct: 328  PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP-GQAGAPGF 386

Query: 861  PGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARGPTG--------KPGPKGTSGGDG 910
            PG  GEKG RG  G   PGP G+ G  GP GS G  G  G        +PGP G  G  G
Sbjct: 387  PGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG 446

Query: 911  PPGPP---GERGPQGPQGPV-------GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK- 959
             PG P   GE G +G +G         G+ GP GP GPPG+ G PG PG +G+ G  G+ 
Sbjct: 447  IPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRD 506

Query: 960  --TGPPGPGGVVGPQGPTGETGPIGE-------RGHPGPPGPPGEQGLPGAAGKEGAKGD 1010
               G PGP G  G  G  G  G  GE       +G  G PG PG+ G+ G AG  G  G 
Sbjct: 507  GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566

Query: 1011 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPP--GPVGSPGERGSAGTA 1068
            PG  G  G  G  GL+   GERG PG  G PG +G  GP GPP  GP G  G++G AG  
Sbjct: 567  PGLPGPKGSPGSVGLK---GERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFP 623

Query: 1069 GPIGLPGRPGPQ----------GPPGPAGEKGAPGEKGPQGPAGRDGVQG---------- 1108
            G  G PG PGP+          GPPG  G  G+PG  GPQG  G  G  G          
Sbjct: 624  GGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGA 683

Query: 1109 ----PVGLPGPAGPAGSPGEDGDKGEIGEPGQ------KGSKGDKGENGPPGP--PGLQG 1156
                 +G PGP GP G  G  GD G  G PG+       G+ G +G+ G PG   PGL+G
Sbjct: 684  VGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKG 743

Query: 1157 PVGAPGIAGGDGE------PGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLP--GP 1205
              G PGI G  GE      PG  G+ G  G  G +G RG PGP   PG +G  G+P  GP
Sbjct: 744  LPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGP 803

Query: 1206 PGEKGENGDVGPMGPPGPPGPRGPQ-----------GPNGADGPQGPPGSVGSVG--GV- 1251
            PG +G  G  GP G  GPPG +G +           GP G  G QG PG  G  G  G+ 
Sbjct: 804  PGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLP 863

Query: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311
            G++G PG  G PG  GE GV G  G+ G  G  G PG  G  G  G PG  GP+G+PG  
Sbjct: 864  GQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923

Query: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE 1371
            G  GD G PG+PG   +  +G  KG+ GD G+ G  GP GE G  G PG  G PG  G  
Sbjct: 924  GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA 983

Query: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPA------GKPGPEGLRGIPGPVGEQGLPGAA 1425
            G+ G+ G KG+ G  G PG  G  GP+G        G PG +G+ GIPGP G  GLPG  
Sbjct: 984  GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 1426 GQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485
            G  G  G  GPPG+    G PG +GEKG  G+ G  G PGE+GEKG  G+PG  GSPG K
Sbjct: 1044 GAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLK 1099

Query: 1486 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            G        G +G PG PGLPG +G KG  G  G  G KG++GLPG PG  GP G+  +P
Sbjct: 1100 GS------PGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEP 1153



 Score =  792 bits (2045), Expect = 0.0
 Identities = 512/1195 (42%), Positives = 581/1195 (48%), Gaps = 171/1195 (14%)

Query: 375  DGDLGEYDFYEYKEYEDKP-----TSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKG 429
            DGD GE     +      P       P  E+   G P    I    + G G  GEKG++G
Sbjct: 292  DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI----VIGTGPLGEKGERG 347

Query: 430  EPAVVEPGMLVEGPPGPAGPAGIMGPPG-----LQGPTGPPGDPGDRG------------ 472
             P    P     G PGP G  G+ G PG     + G  G PG PG+RG            
Sbjct: 348  YPGTPGP----RGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSL 403

Query: 473  --PPGRPGLPGADGLPGPPG----TMLMLPFRYGGDGSKGPT-----------ISAQEAQ 515
              P GR GLPG  G PGPPG    T  ++  + G  G +GP            I  +  +
Sbjct: 404  PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQK 463

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP---PGP 572
             ++ L       RGPPGP G    PG +G PG  GAKG+ G PG  G  GV GP   PG 
Sbjct: 464  GESCLICDIDGYRGPPGPQG---PPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGL 520

Query: 573  TGKPGKRGRPGA----------DGGRGMPGEPGAKGDRGF---DGLPGLPGDKGHRGERG 619
             G+PG +G PG            G  G PG+PG  G  G    DG PGLPG KG  G  G
Sbjct: 521  IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVG 580

Query: 620  PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKG 679
             +G  GPPG  G  G  G+ GP G PG  GP G +G +G  G PG PG  G+ GP G  G
Sbjct: 581  LKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 680  NMGPQGEPGPPGQQGNPGPQGLPGPQGPIG---------PPGEKGPQGKPGLAGLPGADG 730
             + P   PGPPG +G PG  G PGPQG  G          PGEKG  G+PG+ G PG  G
Sbjct: 640  KIVPL--PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPG 696

Query: 731  PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVR--GLKGSKGEKGEDGFPGF 788
            P G  G  G  G  G  G PG  G  G PG +G KG  GV   GLKG  G  G  G PG 
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 789  KGDMGLKGDRGEVGQIGP------RGEDGPEGPKGRAGPTGDPG--PSGQAGEKGKLGVP 840
            KG +G+ G  GE G IGP      RGE GP G  G  G  G PG  P G  G  G  G P
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 841  GLPGYPGRQGPKGSTGFPGF--PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 898
            GL G PG +G KG  GFPG   PG  G+KGA+G+   PG  GQ G  G  G +GA G  G
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL---PGITGQSGLPGLPGQQGAPGIPG 873

Query: 899  KPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 958
             PG KG  G  G PG PG  GP G  G    PG KG  G PG  G  G PG +G+ G  G
Sbjct: 874  FPGSKGEMGVMGTPGQPGSPGPVGAPG---LPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930

Query: 959  KTGPPGP---------GGVVGPQGPTGETGPIGE---RGHPGPPGPPGEQGLPGAAGKEG 1006
              G PG           G  G QG  G+ GPIGE   RG PG PG PG+ G  G  G+ G
Sbjct: 931  LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990

Query: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066
             KGDPG  G  G  G  G +G  G  GLPG  G  G+ G  GPQG PG  G  G +G  G
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050

Query: 1067 TAGP--IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL---PGPAGPAGS 1121
             AGP  IG+PG  G +G  G AG  G+PGEKG +G  G  G+ G  GL   PG  G  GS
Sbjct: 1051 QAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGS 1110

Query: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG---- 1177
            PG  G+KG+ G PG  G  G KGE G PG PG  GP G  G  G DG PG  G++G    
Sbjct: 1111 PGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGL 1170

Query: 1178 -------MFGQKGDEGARG---------------------FPGPPGPIGLQGLPGPPGE- 1208
                     G KGD+G++G                     F GPPGP G  GLPG PG  
Sbjct: 1171 PGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHA 1230

Query: 1209 -KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267
             +G  GD GP G PG PG  GP GP G  G  G  G  G+ G  G  G PG  G+PG  G
Sbjct: 1231 TEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG 1290

Query: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1327
              G+GG  G  G KG+ GPPG  G  G KG PG  G KG+ G  G PG  G PG PGP G
Sbjct: 1291 MPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPG 1350

Query: 1328 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387
               +       G+PG PGP GP G  G  G PG +G  G  G  G  G  G  G  GA G
Sbjct: 1351 PYDI-----IKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPG 1405

Query: 1388 PPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
              G+ GP GP GP G PGP      PGP            DG PG MGPPG P +
Sbjct: 1406 QKGEMGPAGPTGPRGFPGP------PGP------------DGLPGSMGPPGTPSV 1442



 Score =  677 bits (1746), Expect = 0.0
 Identities = 417/947 (44%), Positives = 479/947 (50%), Gaps = 93/947 (9%)

Query: 371  DLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGE 430
            DL + GD G+  F        +  SP  +   PG+P             G+ G KG++G 
Sbjct: 536  DLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH-PGLPGPK-------GSPGSVGLKGERGP 587

Query: 431  PAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPG 490
            P  V       G PG  G  G  GPPG  GP GP GD G  G PG PG PG  G  G PG
Sbjct: 588  PGGV-------GFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 491  TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSG 550
             ++ LP   G +G  G                      GP G  G  G PG  G PG  G
Sbjct: 640  KIVPLPGPPGAEGLPGSP-----------------GFPGPQGDRGFPGTPGRPGLPGEKG 682

Query: 551  AKGESGD--PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG-----FD 603
            A G+ G   PGP GP+GV G PG  G PG  GRPG +G  G PG  G KG+ G       
Sbjct: 683  AVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLK 742

Query: 604  GLPGLPGDKGHRGERGPQGPPGPPGDDG------MRGEDGEIGPRGLPGEAGPRGL--LG 655
            GLPGLPG  G  GE+G  G PG PG+ G      ++G  GE GP GLPG  G  G+  +G
Sbjct: 743  GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIG 802

Query: 656  PRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPG--PPGQQGNPGPQGLPGPQGPIGPPGE 713
            P G  G PG  G  G+ GPPG KG  G  G PG   PG +G+ G QGLPG  G  G PG 
Sbjct: 803  PPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGL 862

Query: 714  KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGL 773
             G QG PG+ G PG+ G  G  G  GQ G  G +G PG  G     G  G  G+ G RG 
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGE---KGDHGFPGSSGPRGD 919

Query: 774  KGSKGEKGEDGFPGFKGDM---------GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824
             G KG+KG+ G PG  G M         G KGD+GE GQIGP GE G  G  G  G  G 
Sbjct: 920  PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGK 979

Query: 825  PGPSGQAGEKGKLGVPGL---PGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881
             G +GQ G+ G  G PG+   PG PG  GPKGS G  G PG  GEKG  G+   PGP+G 
Sbjct: 980  DGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI---PGPQGS 1036

Query: 882  RGPTGPRGSRGARGPTGKPG--------PKGTSGGDGPPGPPGERGPQGPQGPVGFPGP- 932
             G  G +G++G +G  G PG         KG  G  G PG PGE+G +G  G  G PG  
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 933  --KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP- 989
              KG PG  G  G PG PG++G+ G  G  G PG  G  G  G  G TGP G++G PG  
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSD 1156

Query: 990  --PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047
              PG  GE+G PG  G+ G  G PG +G  G  G  G  G  G  G+PG++G  G  G  
Sbjct: 1157 GIPGSAGEKGEPGLPGR-GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPP 1215

Query: 1048 GPQGPPGPVGSPGE-----RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102
            GPQG PG  GSPG      +G  G  G  GLPG PGP GPPG  G  G  G+KG  G  G
Sbjct: 1216 GPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPG 1275

Query: 1103 RDGVQGPVGLPG---PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159
              GV GP G PG     G  GSPG  G KG++G PG  G +G KG  G  G  G QG  G
Sbjct: 1276 APGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQG 1335

Query: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219
             PG  G  G PGP G   +   KG+ G  G  GPPG  GLQGLPGP G++G  G VG  G
Sbjct: 1336 VPGAKGLPGPPGPPGPYDII--KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPG 1393

Query: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1266
            PPG PG  G  G  G  GP GP G  G  G  G  G PG  G PG P
Sbjct: 1394 PPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score =  630 bits (1625), Expect = e-180
 Identities = 408/932 (43%), Positives = 458/932 (49%), Gaps = 127/932 (13%)

Query: 775  GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 834
            G KG+KGE G PG +G +G  G +G      P G  GP G KG  G  G PG  G  G  
Sbjct: 43   GVKGQKGERGLPGLQGVIGFPGMQG------PEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 835  GKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 894
            G  G PG PG PG  G  G  G PG PG NG KG RG  G PG  G  G  GP G  G +
Sbjct: 97   GASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMK 156

Query: 895  GPTGK----------PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944
            G  G+           G +G  G  G PGPPG  G QGP GP GF GP GPPGPPG    
Sbjct: 157  GDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP--- 213

Query: 945  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG-----ETGPIGERGHPGPPGPPGEQGLP 999
            PG  GQ G   FQG  G  G  GV GP G  G     E G    +G  G  G PG QG+P
Sbjct: 214  PGEKGQMG-LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMP 272

Query: 1000 GAAGKEGAKGDPGPQGISGKDGPAGLRG---FPGERGLPGA---QGAPGLKGGEGPQGPP 1053
            G  G++G  G PGP+G  GKDG  G +G   FPGE G PG    QG  G KG  GP GPP
Sbjct: 273  GV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPP 331

Query: 1054 G------PVGSPGERGSAGTAGPIG---------LPGRPGPQG--PPGPAGEKGAPGEKG 1096
            G      P+G  GERG  GT GP G         LPG+PGP G   PG AG  G PGE+G
Sbjct: 332  GIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERG 391

Query: 1097 PQG-----------PAGRDGVQGPVGLPGPAGPAG--------SPGEDGDKGEIGEPGQK 1137
             +G           P+GRDG+ GP G PGP G  G         PG  GD+G  G PGQ 
Sbjct: 392  EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQP 451

Query: 1138 G------SKGDKGEN-------GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD 1184
            G       KG KGE+       G  GPPG QGP   PG  G  G+PG +G +G+ G+ G 
Sbjct: 452  GFIGEIGEKGQKGESCLICDIDGYRGPPGPQGP---PGEIGFPGQPGAKGDRGLPGRDGV 508

Query: 1185 EGARGFPGPPGPIGLQGLPGPPGE-------KGENGDVGPMGPPGPPGPRGPQGPNGADG 1237
             G  G  G PG IG  G  G PGE       KG+ GD G  G PG  G  G  G +G  G
Sbjct: 509  AGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPG 568

Query: 1238 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297
              GP GS GSVG  GE+G PG  G PG  G+ G  GP G  G  G  G  G AG PG  G
Sbjct: 569  LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPG 627

Query: 1298 PPGDDGPKGNPGP-VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356
             PG  GPKG PG  V  PG PG  G PG  G  G  GD+G  G PG+PG PG  G  G P
Sbjct: 628  SPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQP 687

Query: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP--------EG 1408
            G  G  GPPG  G +G  G+ G  G  G  G  G  G  G QG  G+PG          G
Sbjct: 688  GI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPG 746

Query: 1409 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL--IGPPGE 1466
            L GIPG  GE+G  G  G  G  G +GPPGL G++G+PG  G  G  G  G+  IGPPG 
Sbjct: 747  LPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGA 806

Query: 1467 QGEKGDRGLPGTQGSPGAKGDGG--------IPGPAGP---------LGPPGPPGLPGPQ 1509
            +G  G +G PG  G PG KG+ G        +PGP G           G  G PGLPG Q
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866

Query: 1510 GPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADDNI 1569
            G  G  G  G  G+ G  G PG PGSPGP G      P L  +K      G      D  
Sbjct: 867  GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG-----APGLPGEKGDHGFPGSSGPRGDPG 921

Query: 1570 LDYSDGMEEIFGSLNSL-KQDIEHMKFPMGTQ 1600
            L    G   + G   S+ K D+  MK   G Q
Sbjct: 922  LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953



 Score =  605 bits (1561), Expect = e-173
 Identities = 374/833 (44%), Positives = 433/833 (51%), Gaps = 97/833 (11%)

Query: 396  PPNEEFGPGVPA----ETDITETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPA 450
            PP  E  PG P     + D       G  G  GEKG  G+P +        G PGP GP 
Sbjct: 647  PPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI--------GFPGPPGPK 698

Query: 451  GIMGPPGLQGPTGPPGDPGDRGPPGRPG-----------LPGADGLPGPPGTMLMLPFRY 499
            G+ G PG  GP G PG PG  G PG PG           LPG  GLPG PG    +P   
Sbjct: 699  GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPG----IPGTP 754

Query: 500  GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG--D 557
            G  GS G  +     +  AI         GPPG  G+ G PGP G PGS G+ G  G   
Sbjct: 755  GEKGSIG--VPGVPGEHGAI---------GPPGLQGIRGEPGPPGLPGSVGSPGVPGIGP 803

Query: 558  PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGE 617
            PG +GP G QGPPG +G PG +G  G  G  G+   PG KGD+G  GLPG+ G  G  G 
Sbjct: 804  PGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGL 862

Query: 618  RGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 677
             G QG PG PG  G +GE G +G  G PG  GP G  G  G  G  G PG +G  G PG 
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL 922

Query: 678  KGNMGPQGEPGPPGQQGN------PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGP 731
            KG+ G  G PG PG           G +G  G +G IGP GEKG +G PG  G+PG DG 
Sbjct: 923  KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982

Query: 732  PGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGD 791
             G PG+ G  G+ G  G PG  G    PGP   KG+ G  GL G+ GEKG  G PG +G 
Sbjct: 983  AGQPGQPGPKGDPGISGTPGAPG---LPGP---KGSVGGMGLPGTPGEKGVPGIPGPQGS 1036

Query: 792  MGLKGDRG---EVGQIGPRGEDGP--EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846
             GL GD+G   E GQ GP G   P   G KG  G  G PG  G+ GEKG +G+PG+PG P
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906
            G +G  GS G+PG PG  GEKG +G+   PG  G  G  G  G  G  GPTG  G KG  
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGL---PGLDGIPGVKGEAGLPGTPGPTGPAGQKGEP 1153

Query: 907  GGDGPPGPPGERGPQG--PQGPVGFPGPKGPPGP------PGKDGLPGHPGQRGETGFQG 958
            G DG PG  GE+G  G   +G  GFPG KG  G       PG  G PG PG +GE GF G
Sbjct: 1154 GSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMG 1213

Query: 959  KTGPPGPGGVVGP-----QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013
              GP G  G+ G      +GP G+ GP G+ G PG PGP G  GLPG  G +G KG+PG 
Sbjct: 1214 PPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGW 1273

Query: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG------PVGSPGERGSAGT 1067
             G  G  GP   +G PG +G+PG  G+PG+ G +G  GPPG      P G PG +G  G 
Sbjct: 1274 PGAPGVPGP---KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 1068 AGPIGLPGR---PGPQGPPGP----AGEKGAPGEKGPQGPAGRDGVQGP------VGLPG 1114
             G  G+PG    PGP GPPGP     GE G PG +GP G  G  G+ GP       GL G
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390

Query: 1115 PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1167
              GP G PG DG  G+ GE G  G  G +G  GPPGP GL G +G PG    D
Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443



 Score =  558 bits (1437), Expect = e-158
 Identities = 340/735 (46%), Positives = 388/735 (52%), Gaps = 97/735 (13%)

Query: 889  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP---------VGFPGPKGPPGPP 939
            G     G  G+ G +G  G  G  G PG +GP+GPQGP          G PG KG  GPP
Sbjct: 37   GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 940  GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999
            G  G PG+PG     G  G+ GPPGP G+ G  G  GE GP+      GPPG PG  G P
Sbjct: 97   GASGYPGNPGL---PGIPGQDGPPGPPGIPGCNGTKGERGPL------GPPGLPGFAGNP 147

Query: 1000 GAAGKEGAKGDPGP-------QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
            G  G  G KGDPG          + G+ G  G+ G PG  GLPG QG  G  G  GP GP
Sbjct: 148  GPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGP 207

Query: 1053 PGPVGSPGERGSAGTA--GPIGLPGRPGPQGPPGPAG-----EKGAPGEKGPQGPAGRDG 1105
            PGP G PGE+G  G +  GP G  G  G  GPPG  G     EKG    KG +G  G  G
Sbjct: 208  PGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPG 267

Query: 1106 VQGPVGL-----PGPAGPAGSPGEDGDKGEIGEP------------GQKGSKGDKGENGP 1148
             QG  G+     PG  GP G PG+DGDKGE G P            G++G +G+KGE GP
Sbjct: 268  FQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP 327

Query: 1149 PGPPGL---QGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG-PI-GLQGLP 1203
            PGPPG+    GP+G  G  G  G PGPRG+    G KG  G  G PGPPG P+ G  G P
Sbjct: 328  PGPPGIVIGTGPLGEKGERGYPGTPGPRGEP---GPKGFPGLPGQPGPPGLPVPGQAGAP 384

Query: 1204 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGE--KGEPGEAG 1261
            G PGE+GE GD G  G    PGP G  G  G  G  GPPG  G   G+ E   G PG+ G
Sbjct: 385  GFPGERGEKGDRGFPG-TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQG 443

Query: 1262 NPGPPGEAGVGGPKGERGEKGEA----------GPPGAAGPPGAKGPPGDDGPKGN---P 1308
             PG PG+ G  G  GE+G+KGE+          GPPG  GPPG  G PG  G KG+   P
Sbjct: 444  PPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLP 503

Query: 1309 GPVGFPGDPGPPGEPGPAGQDGVGGD----------KGEDGDPGQPGPPGPSGEAGPP-- 1356
            G  G  G PGP G PG  GQ G  G+          KG+ GDPG PG PG +G AG P  
Sbjct: 504  GRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGR 563

Query: 1357 -GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--QGPAGKPGPEGLRGIP 1413
             G PG  GP G+ G+ G +GE+G  G  G  G  G TGP GP   GPAG  G +G  G P
Sbjct: 564  DGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFP 623

Query: 1414 GPVGEQGLPGAAGQDGP----PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1469
            G  G  GLPG  G+ G     PGP G  GLPG  G PG +G++G PG  G  G PGE+G 
Sbjct: 624  GGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGA 683

Query: 1470 KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGPKGNKGSTGPAGQKGD 1526
             G  G+ G  G PG KG  G+PG  GP G PG P   GLPG  G +G KG  G  G  G 
Sbjct: 684  VGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGL 741

Query: 1527 SGLPGPPGSPGPPGE 1541
             GLPG PG PG PGE
Sbjct: 742  KGLPGLPGIPGTPGE 756



 Score =  465 bits (1196), Expect = e-130
 Identities = 289/627 (46%), Positives = 320/627 (51%), Gaps = 97/627 (15%)

Query: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA---PGLKGGEGPQGPP---GPVG 1057
            +  AKG     G  GK    G++G  GERGLPG QG    PG++G EGPQGPP   G  G
Sbjct: 24   RAAAKGGCAGSGC-GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTG 82

Query: 1058 SPGERGSAGTAGP---------IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108
             PG  G+ GT GP          GLPG PG  GPPGP G  G  G KG +GP       G
Sbjct: 83   EPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPL------G 136

Query: 1109 PVGLPGPAGPAGSPGEDGDKGEIGE----------PGQKGSKGDKGENGPPGPPGLQGPV 1158
            P GLPG AG  G PG  G KG+ GE           G++G  G  G  GPPG PGLQGPV
Sbjct: 137  PPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPV 196

Query: 1159 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG--------EKG 1210
            G PG  G  G PGP G  G  GQ G      F GP G  G QG+ GPPG        EKG
Sbjct: 197  GPPGFTGPPGPPGPPGPPGEKGQMG----LSFQGPKGDKGDQGVSGPPGVPGQAQVQEKG 252

Query: 1211 ENGDVGPMGPPGPPGPRGPQ--GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
            +    G  G  G PG +G    G  G  G  GP G  G  G  GEKG PG  G PG PG 
Sbjct: 253  DFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGL 312

Query: 1269 AGVGGPKGERGEKGEAGPPG---AAGPPGAKGP---PGDDGPKGNPGPVGF---PGDPGP 1319
             G  GP+GE+GE G  GPPG     GP G KG    PG  GP+G PGP GF   PG PGP
Sbjct: 313  IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372

Query: 1320 PG--EPGPAGQDGVGGDKGEDGDPGQPGP--PGPSGEAGPPGPPGKRGPPGAAG-----A 1370
            PG   PG AG  G  G++GE GD G PG   PGPSG  G PGPPG  GPPG  G      
Sbjct: 373  PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432

Query: 1371 EGRQGEKGAKGEAGAEGPPGKTGPV-------------------GPQGPAGKPGPEGLRG 1411
            E + G  G +G  G  G PG  G +                   GP GP G PG  G  G
Sbjct: 433  ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492

Query: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGL---PGLKGDP----------GSKGEKGHPGLI 1458
             PG  G++GLPG  G  G PGP G PGL   PG KG+P          G KG+ G PG  
Sbjct: 493  QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQP 552

Query: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518
            G+ G  G  G  G  GLPG +GSPG+ G  G  GP G +G PG  G  GP GP G  G  
Sbjct: 553  GMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG-YGPA 611

Query: 1519 GPAGQKGDSGLPGPPGSPGPPGEVIQP 1545
            GP G KG +G PG PGSPG PG   +P
Sbjct: 612  GPIGDKGQAGFPGGPGSPGLPGPKGEP 638


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  913 bits (2359), Expect = 0.0
 Identities = 543/1302 (41%), Positives = 675/1302 (51%), Gaps = 122/1302 (9%)

Query: 550  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGL-PG- 607
            G KG++G PGP GP G+   PGP+GK G RG PG  G  G+PG PG KG +G  G  PG 
Sbjct: 489  GPKGDTGPPGPPGPAGI---PGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQ 545

Query: 608  -LPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQP 666
             +PG+KG +G  G  GPPG  GD G++G     G  GLPGE G  G  G  G+PG PG+ 
Sbjct: 546  PVPGEKGDQGLSGLMGPPGMQGDKGLKGHP---GLPGLPGEQGIPGFAGNIGSPGYPGRQ 602

Query: 667  GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLP---------GPQGPIGPPGEKGPQ 717
            G+AG +G PGPKG  G  G PG  GQ G  G +G+P         G QG  G  G++GP 
Sbjct: 603  GLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662

Query: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777
            G  G  GL G  GPPG PG       +G++GP GP GP G PGP G+ G    +GL G K
Sbjct: 663  GLDGSPGLVGGTGPPGFPGL------RGSVGPVGPIGPAGIPGPMGLSGN---KGLPGIK 713

Query: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837
            G+KGE G  G  G+ G  GD+G VG  GP G  G  GP G+   TGDPG  G +G  G  
Sbjct: 714  GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQ---TGDPGLQGPSGPPGPE 770

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 897
            G PG  G PG+ GP+G  G  G  G  G  G +G  G+ GP G  G  GPRG  G +G  
Sbjct: 771  GFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYA 830

Query: 898  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957
            G+PGP+G  G  G  G  G+ G  GP G  G  G  G  G  G+ G PG  G +GE G  
Sbjct: 831  GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVM 890

Query: 958  GKTGPPGPGGVVGP---------QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1008
            G  GPPG  G +GP         +GP G  GP G+RG  GP G  GEQG+ GA G++G +
Sbjct: 891  GYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQ 950

Query: 1009 GDPGPQGISGKDGPAGLRGF---PGERGLPGA------QGAPGLKGGEGPQGPPGPVGSP 1059
            G  GP G+ GK G  G RGF   PG +GLPG+       G PGL+G +G  GPPG +G  
Sbjct: 951  GKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGME 1010

Query: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPA 1119
            G  G+ G +G  G PG  G  G  G  G  G PG +G  G  G +G+QG  GL G  G  
Sbjct: 1011 GPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGR 1070

Query: 1120 GSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP---GLQGPVGAPGIAGGDGEPGP---- 1172
            G PGEDG+KGE+G PG  G  G  G+ G PGP    G+ G  G PG  G  G+ GP    
Sbjct: 1071 GLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEV 1130

Query: 1173 --RGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230
              RG  G  G+ G +GARG  G  G +GL G  G PG  G  G  G  GP G PGP+G +
Sbjct: 1131 GSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEK 1190

Query: 1231 GPNGAD----GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGP 1286
            G  G D    GP GP G  G VG  GE+GEPG  G  G  G  G+ G  G++G  GE G 
Sbjct: 1191 GYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD 1250

Query: 1287 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346
             G  G  G +G  G+ G KG PGP G PG PG  G  GP G  G  G  G  G+PG+ GP
Sbjct: 1251 QGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGP 1310

Query: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
            PG        G PG RG PG  G  G  G  G KG +G  G PG  GP G QG  G+PG 
Sbjct: 1311 PGKQ------GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGI 1364

Query: 1407 EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGE 1466
            +G RG  G  G+QG  G  G  G PG  G  GL G +G PG KG +G  G++G+ GP G 
Sbjct: 1365 QGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGP 1424

Query: 1467 QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD 1526
             G +G+ G  G +         GI GP G  GP G  G  G  GP+G +G  GP      
Sbjct: 1425 IGHRGNTGPLGRE---------GIIGPTGRTGPRGEKGFRGETGPQGPRGQPGP------ 1469

Query: 1527 SGLPGPPGSPGP--PGEVIQPLPILSSKKTRRHTEGMQADADDNILDYSDGMEEIFGSLN 1584
               PGPPG+PGP    ++   +  L    T    E  Q + +  ++D+S   EEIF +LN
Sbjct: 1470 ---PGPPGAPGPRKQMDINAAIQALIESNTALQMESYQ-NTEVTLIDHS---EEIFKTLN 1522

Query: 1585 SLKQDIEHMKFPMGTQTNPARTCKDLQLSHPDFPDGEYWIDPNQGCSGDSFKVYCNFTSG 1644
             L   +  +K P+GT+ NPAR CKDL        DG+YWIDPN GC  D+ +V+CNF++G
Sbjct: 1523 YLSNLLHSIKNPLGTRDNPARICKDLLNCEQKVSDGKYWIDPNLGCPSDAIEVFCNFSAG 1582

Query: 1645 GETCIYPDKKSEGVRISSWPKEKPGSWFSEFKRGKLLSYLDVEGNSINMVQMTFLKLLTA 1704
            G+TC+ P   ++                 EF  GK              VQM FL LL++
Sbjct: 1583 GQTCLPPVSVTK----------------LEFGVGK--------------VQMNFLHLLSS 1612

Query: 1705 SARQNFTYHCHQSAAWYDVSSGSYDKALRFLGSNDEEMSYDNNPFIKTLYDGCASRKG-Y 1763
             A    T HC  +  W    +      + F G N +    +     K L D C  + G +
Sbjct: 1613 EATHIITIHCLNTPRWTSTQTSGPGLPIGFKGWNGQIFKVNTLLEPKVLSDDCKIQDGSW 1672

Query: 1764 EKTVIEINTPKIDQVPIVDVMINDFGDQNQKFGFEVGPVCFL 1805
             K     +T + +Q+P+++V         +K+  +   VCFL
Sbjct: 1673 HKATFLFHTQEPNQLPVIEVQKLPHLKTERKYYIDSSSVCFL 1714



 Score =  733 bits (1892), Expect = 0.0
 Identities = 440/1035 (42%), Positives = 521/1035 (50%), Gaps = 81/1035 (7%)

Query: 380  EYDFYEYKEYEDKPT--------SPPNEEFGPGVPAETDITETS-------INGH----- 419
            E + Y+Y  YED  T         P  +   PG P    I   S       I G      
Sbjct: 466  ETELYDYYYYEDLNTMLEMEYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPG 525

Query: 420  --GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDP--------- 468
              G  G KG KG+P    PG  V G  G  G +G+MGPPG+QG  G  G P         
Sbjct: 526  LPGLPGPKGPKGDPGF-SPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584

Query: 469  ---------GDRGPPGRPGLPGADGLPGPPGTMLML-----PFRYGGDGSKG-PTISAQE 513
                     G  G PGR GL G +G PGP G    +       + G +G +G P I  ++
Sbjct: 585  GIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKK 644

Query: 514  AQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPT 573
                   +Q      G  GP GL G PG VGG G  G  G  G  GP GP G  G PGP 
Sbjct: 645  GFKG---RQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPM 701

Query: 574  GKPGKRGRPGADGGRGMP------GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP--- 624
            G  G +G PG  G +G        GEPG  GD+G  GLPG PG +G  G  G  G P   
Sbjct: 702  GLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQ 761

Query: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684
            GP G  G  G  G+IG  G  G  GP+GLLG RG PG PG  G  G +GP G  G +GP+
Sbjct: 762  GPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPR 821

Query: 685  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
            G+PG  G  G PGP+GL   +G +G  G  G  G+ G  GLPG  G  G  G++G+ G  
Sbjct: 822  GKPGQKGYAGEPGPEGL---KGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSP 878

Query: 745  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
            G LGP G +G +GYPGP GV G  G  GL G  G +G  G  G KG  G +G  G +G+ 
Sbjct: 879  GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938

Query: 805  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 864
            G +G  G +G +G+ GP G  G +G  GE+G  G PGL G P      GSTG  G PG  
Sbjct: 939  GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLP------GSTGDRGLPGEP 992

Query: 865  GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ 924
            G +G +G  G PG  G  GP G  G  G +G  G  G  GT+G  G  G PG RG  G  
Sbjct: 993  GLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAP 1052

Query: 925  GPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGER 984
            G  G  G  G  G PG  GLPG  G++GE G  G  GP G  G  G  GP G  G  G+R
Sbjct: 1053 GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQR 1112

Query: 985  GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLK 1044
            G    PG  G++G  G  G+ G++G PG  G SG  G  G RG  G  GL G  G PG+ 
Sbjct: 1113 GR---PGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIP 1169

Query: 1045 GGEGPQGPPGPVGSPGERGSAGTAGPIG-LPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1103
            G  G QG PGP G PG +G  G  G    + G PGP+G PGP G++G  GE G +G  G 
Sbjct: 1170 GYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229

Query: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGA 1160
             GV G  G  G  GP G PG+ G++G  GE G +G+KG KG  GP   PG PGLQG +G 
Sbjct: 1230 VGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGP 1289

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220
             GI G  G  G  G  G  G  G +G  G  G PG  GL G PGPPG KG +      G 
Sbjct: 1290 KGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSS------GL 1343

Query: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
            PG PG +GP+G  G  G  G  G  G  G  G++G  G+ G  G PGE GV G  G +G 
Sbjct: 1344 PGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGF 1403

Query: 1281 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1340
             G  GP G AG  G  GP G  G +GN GP+G  G  GP G  GP G+ G  G+ G  G 
Sbjct: 1404 PGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP 1463

Query: 1341 PGQPGPPGPSGEAGP 1355
             GQPGPPGP G  GP
Sbjct: 1464 RGQPGPPGPPGAPGP 1478



 Score =  731 bits (1886), Expect = 0.0
 Identities = 444/1022 (43%), Positives = 520/1022 (50%), Gaps = 95/1022 (9%)

Query: 442  GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LMLPFRY 499
            GPPGP GPAGI GP G +GP G PG  G+   PG PGLPG  G  G PG      +P   
Sbjct: 495  GPPGPPGPAGIPGPSGKRGPRGIPGPHGN---PGLPGLPGPKGPKGDPGFSPGQPVPGEK 551

Query: 500  GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG 559
            G  G  G  +     Q    L+     L G PG  G+ G  G +G PG  G +G +G  G
Sbjct: 552  GDQGLSG-LMGPPGMQGDKGLK-GHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEG 609

Query: 560  PQGPRGVQG------------PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 607
              GP+G QG            P G  G PG RG+ G  G +G PG+ G +G  G DG PG
Sbjct: 610  NPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPG 669

Query: 608  L------PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 661
            L      PG  G RG  GP GP GP G  G  G  G  G  G+ G+ G +G  G  G PG
Sbjct: 670  LVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG 729

Query: 662  APGQPGMAGVDGPPGPKGNMGP---------QGEPGPPGQQGNPGPQGLPGPQGPIGPPG 712
             PG  G  G+ GPPG +G  GP         QG  GPPG +G PG  G+PG  GP GP  
Sbjct: 730  YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGP-- 787

Query: 713  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 772
                       GL G  GPPG PG +G  GE+G +G  G  GP G PG +G  G  G  G
Sbjct: 788  ----------KGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837

Query: 773  LKGSKGEKGEDGFPGFKGDMGLKGD---RGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 829
            LKG  G++G  G  G  G +GL G+    G +G+ G RG  GP GP+G  G  G PGP G
Sbjct: 838  LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897

Query: 830  QAGEKGKLGVP---GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP-- 884
              G  G LG+P   G  G PG QGPKG  G  G  G  GE+G +G  G+ G +G+RGP  
Sbjct: 898  VPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHG 957

Query: 885  ----TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940
                TG  G RG +G  G  G  G++G  G PG PG RG QG  GP G  G +GPPG  G
Sbjct: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEG 1017

Query: 941  KDGLPGHPGQRGETGFQGK---TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 997
            + GL G PG +G+ G  G    TG PG  G  G  G  G  G  G +G PG  G PGE G
Sbjct: 1018 ESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG 1077

Query: 998  LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG--GE-GPQGPPG 1054
              G  G  G  G  G  G +G  GP G+ G PG+RG PG +G  G  G  GE G +GPPG
Sbjct: 1078 EKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 1055 PVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG--- 1111
             +G  G +G+ GT G +G  G  GP G PG  G +G  G+ GP G  G  G +G  G   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 1112 -LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1170
             + GP GP G PG  GD+GE GEPG +G KG  G  G  G  G QGP G PG  G  G  
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 1171 GPRGQQGMFGQKGDEGARGFPGPP------GPIGLQGLPGPPGEKGENGDVGPMGPPGPP 1224
            G RG +G  G+KG  G  G PG P      GP G+QG  G  G  G  G +GP G  G P
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLP 1317

Query: 1225 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA 1284
            G RG  G  G  G  GPPG  GS G  G  G  G  G  G PG+ G+ G +G RG +G+ 
Sbjct: 1318 GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQ 1377

Query: 1285 GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQP 1344
            GP    G PG KG PG+ G +   G  GF G PGP G  G AG  G+ G KG  G  G  
Sbjct: 1378 GP---CGDPGLKGQPGEYGVQ---GLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431

Query: 1345 GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP 1404
            GP G  G  GP G  G R            GEKG +GE G +GP G+    GP GP G P
Sbjct: 1432 GPLGREGIIGPTGRTGPR------------GEKGFRGETGPQGPRGQP---GPPGPPGAP 1476

Query: 1405 GP 1406
            GP
Sbjct: 1477 GP 1478



 Score =  647 bits (1669), Expect = 0.0
 Identities = 375/805 (46%), Positives = 426/805 (52%), Gaps = 46/805 (5%)

Query: 773  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPS-GQA 831
            L+G KG+ G  G PG  G  G  G RG  G  GP G  G  G  G  GP GDPG S GQ 
Sbjct: 487  LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQP 546

Query: 832  --GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK------PGPRGQRG 883
              GEKG  G+ GL G PG QG KG  G PG PG  GE+G  G AG       PG +G  G
Sbjct: 547  VPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAG 606

Query: 884  PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDG 943
            P G  G +GA+G  G PG  G  G +G  G PG RG +G +G  GFPG  G  GP G DG
Sbjct: 607  PEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDG 666

Query: 944  LPGHPGQRGETGFQG------KTGPPGPGGVVGP------------QGPTGETGPIGERG 985
             PG  G  G  GF G        GP GP G+ GP            +G  GE G  GE G
Sbjct: 667  SPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELG 726

Query: 986  HPGPPGPPGEQGLPGAAG---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA---QG 1039
             PG PG  G  GLPG  G   K G  G  G  G+ G  GP G  GFPG+ G+PG    +G
Sbjct: 727  EPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEG 786

Query: 1040 APGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQG 1099
              GL G  GP GPPG  G+ GE G  G  G +G  G+PG +G  G  G +G  GE G QG
Sbjct: 787  PKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQG 846

Query: 1100 PAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVG 1159
              G+ G  GPVGLPG  G  GS GE   KGE G PG  G +G+KG  G PGPPG+ GP+G
Sbjct: 847  NIGKIGETGPVGLPGEVGMTGSIGE---KGERGSPGPLGPQGEKGVMGYPGPPGVPGPIG 903

Query: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMG 1219
              G+ G  G  GP G QG  GQ+G  G      P G +G QG+ G  GEKG+ G  GP G
Sbjct: 904  PLGLPGHVGARGPPGSQGPKGQRGSRG------PDGLLGEQGIQGAKGEKGDQGKRGPHG 957

Query: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERG 1279
              G  G  G +G  G  G QG PGS G  G  GE G  G  G+ GPPGE G+ GP G  G
Sbjct: 958  LIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEG 1017

Query: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1339
            E G  G PGA G  G  G  G  G  G  G  G PG+ G  G+ G  G  G  G  GEDG
Sbjct: 1018 ESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDG 1077

Query: 1340 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1399
            + G+ G PG  G  G  G  G  GP G  G  G++G  G KG+ G  GP G+ G  GP G
Sbjct: 1078 EKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPG 1137

Query: 1400 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG--- 1456
              GK GP+G RG  G VG  GL G  G+ G PG  G  G PG  G PG KGEKG+PG   
Sbjct: 1138 KIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDS 1197

Query: 1457 -LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1515
             ++G  GP GE G  GD+G  G  G+ G KG  G+PG  G  G  GPPG PG QG +G K
Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257

Query: 1516 GSTGPAGQKGDSGLPGPPGSPGPPG 1540
            G  G  G KG  G PGP G PG PG
Sbjct: 1258 GERGSEGNKGKKGAPGPSGKPGIPG 1282



 Score =  344 bits (882), Expect = 5e-94
 Identities = 236/572 (41%), Positives = 276/572 (48%), Gaps = 76/572 (13%)

Query: 375  DGDLGEYDFYEYK-EYEDKPTSPPNEEFGP-GVPAETDIT-ETSING-HGAYGEKGQKGE 430
            DG LGE      K E  D+    P+   G  G P E     +  + G  G+ G++G  GE
Sbjct: 932  DGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991

Query: 431  PA-------VVEPG-MLVEGPPGPAGPAGIMGPPGLQGP---------TGPPGDPGDRGP 473
            P        V  PG M +EGPPG  G +G+ G PG +G          TG PG  G+ G 
Sbjct: 992  PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGA 1051

Query: 474  PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533
            PG  GL G DGL G PG    LP   G DG KG     +      I    R    G PGP
Sbjct: 1052 PGEEGLQGKDGLKGVPGGR-GLP---GEDGEKG-----EMGLPGIIGPLGRSGQTGLPGP 1102

Query: 534  MGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGA--------- 584
             G+ G PG  G PG  G KG+ G  G  G RG  G  G +G  G RG  GA         
Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER-------GPQGPPGPPGDDGMRGEDG 637
            DG  G+PG  G +G  G  GLPG  G+KG+ GE        GP+G PGP GD G RGE G
Sbjct: 1163 DGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPG 1222

Query: 638  EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPG 697
              G +G  G  G RG  G +G PG PG  G  G+ G  G +GN G +G PGP G+ G PG
Sbjct: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282

Query: 698  PQGLPGPQG---------------PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 742
             QGL GP+G                IGPPG+   QG PG+ G PG  G  G PG  G  G
Sbjct: 1283 LQGLLGPKGIQGYHGADGISGNPGKIGPPGK---QGLPGIRGGPGRTGLAGAPGPPGVKG 1339

Query: 743  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
              G  G PG QGP G  G  G  G  G RG +G++G++G  G PG KG  G  G +G  G
Sbjct: 1340 SSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTG 1399

Query: 803  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862
              G  G  GPEG  G  G +G  GP G  G  G LG  G+ G  GR GP+G         
Sbjct: 1400 FQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRG--------- 1450

Query: 863  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 894
               EKG RG  G  GPRGQ GP GP G+ G R
Sbjct: 1451 ---EKGFRGETGPQGPRGQPGPPGPPGAPGPR 1479



 Score =  325 bits (832), Expect = 3e-88
 Identities = 196/439 (44%), Positives = 226/439 (51%), Gaps = 51/439 (11%)

Query: 1140 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199
            +G KG+ GPPGPPG   P G PG +G       RG +G+ G  G+ G  G PGP GP G 
Sbjct: 488  RGPKGDTGPPGPPG---PAGIPGPSG------KRGPRGIPGPHGNPGLPGLPGPKGPKGD 538

Query: 1200 QGL-PGPP--GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256
             G  PG P  GEKG+ G  G MGPPG  G +G +G  G  G  G  G  G  G +G  G 
Sbjct: 539  PGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGY 598

Query: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316
            PG  G  GP G  G   PKG +G  G  G  G  GP G +G PG  G KG  G  GFPGD
Sbjct: 599  PGRQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGD 655

Query: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1376
             G   + GPAG DG  G  G  G PG PG  G  G  GP GP G  GP G +G +G  G 
Sbjct: 656  FG---DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGI 712

Query: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGP 1436
            KG KGE G  G  G+ G  G +G  G PGP G+RG  GP G+ G PG  G  GPPG   P
Sbjct: 713  KGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPG---P 769

Query: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP---------GTQGSPGAKGD 1487
             G PG  G PG  G +G  GL+G  GPPG  G KG +G           G +G PG KG 
Sbjct: 770  EGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGY 829

Query: 1488 GGIPGP------------------AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGL 1529
             G PGP                   GP+G PG  G+ G  G KG +GS GP G +G+ G+
Sbjct: 830  AGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGV 889

Query: 1530 ---PGPPGSPGPPGEVIQP 1545
               PGPPG PGP G +  P
Sbjct: 890  MGYPGPPGVPGPIGPLGLP 908



 Score =  234 bits (597), Expect = 6e-61
 Identities = 154/383 (40%), Positives = 183/383 (47%), Gaps = 61/383 (15%)

Query: 397  PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVV----EPGMLVEGPPGPAGPAG- 451
            P  + G   P     T  ++   G  G  G+ G P       +PG    G PGP G  G 
Sbjct: 1135 PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGP--SGLPGPKGEKGY 1192

Query: 452  ------IMGPPGLQGPTGPPGDPGDRGPPGR---------PGLPGADGLPGPPGTMLMLP 496
                  ++GPPG +G  GP GD G+RG PG          PGL GA G  GPPG     P
Sbjct: 1193 PGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGE----P 1248

Query: 497  FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPG------PVGGPGSSG 550
               G  G KG   S           +     +G PGP G  G PG      P G  G  G
Sbjct: 1249 GDQGEQGLKGERGS-----------EGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297

Query: 551  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGR------PGADGGRGMPGEPGAKGDRGFDG 604
            A G SG+PG  GP G QG PG  G PG+ G       PG  G  G+PG PG +G +G  G
Sbjct: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357

Query: 605  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 664
            LPG PG +G RG RG QG  GP GD G++G+         PGE G +GL G +G PG  G
Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQ---------PGEYGVQGLTGFQGFPGPKG 1408

Query: 665  QPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAG 724
              G AG+ G  GPKG +G +G  GP G++G  GP G  GP+G  G  GE GPQG     G
Sbjct: 1409 PEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGP---RG 1465

Query: 725  LPGADGPPGHPGKEGQSGEKGAL 747
             PG  GPPG PG   Q     A+
Sbjct: 1466 QPGPPGPPGAPGPRKQMDINAAI 1488



 Score =  131 bits (329), Expect = 7e-30
 Identities = 87/196 (44%), Positives = 100/196 (51%), Gaps = 29/196 (14%)

Query: 1407 EGLRGIPGPVGEQGLPGAAGQDGP---------PGPMGPPGLPGL------KGDPGSK-- 1449
            E LRG  G  G  G PG AG  GP         PGP G PGLPGL      KGDPG    
Sbjct: 485  EYLRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG 544

Query: 1450 ----GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505
                GEKG  GL GL+GPPG QG+KG +G PG    PG  G+ GIPG AG +G PG PG 
Sbjct: 545  QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGL---PGLPGEQGIPGFAGNIGSPGYPGR 601

Query: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGMQADA 1565
             G  GP+GN    GP G +G  G PG  G  GP GE  + +P +  KK  +  +G   D 
Sbjct: 602  QGLAGPEGN---PGPKGAQGFIGSPGEAGQLGPEGE--RGIPGIRGKKGFKGRQGFPGDF 656

Query: 1566 DDNILDYSDGMEEIFG 1581
             D      DG   + G
Sbjct: 657  GDRGPAGLDGSPGLVG 672



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 65/270 (24%), Positives = 117/270 (43%), Gaps = 24/270 (8%)

Query: 80  AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQSFLLSIYNEHGIQQIGVEVGRSPVFLF 139
           A +  P  ++ P     + F+IL  ++  +   +FL SI N++ +Q +GV++   P  L 
Sbjct: 88  AYIETPFVKILPVN-LGQPFTILTGLQSHRVNNAFLFSIRNKNRLQ-LGVQL--LPKKLV 143

Query: 140 EDHTGK-PAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV 198
               GK PA  +Y      ++ D +WH  AI++  ++V+M V+C KK        E    
Sbjct: 144 VHIRGKQPAVFNY------SVHDEQWHSFAITIRNQSVSMFVECGKKYFSTETIPEVQTF 197

Query: 199 DTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEP-- 256
           D+N +   G+   +   FEG + Q  I    +A+ DYC +    C  +     +   P  
Sbjct: 198 DSNSVFTLGSMNNNSIHFEGIVCQLDIIPSAEASADYCRYVKQQCRQADKYQPETSIPCT 257

Query: 257 -----QIDEYAPEDIIEYDYEYGEAEYKEAESVTEGPTVTEETIAQTEANIVDDFQEYNY 311
                +I E++P   +  +    E  + E +S+        ET+ + + + +   Q    
Sbjct: 258 TLIPTKIPEHSPPPKLFAEKVLSEDTFTEGKSIPNIIKNDSETVYKRQEHQISRSQ---- 313

Query: 312 GTMESYQTEAPRHVSGTNEPNPVEEIFTEE 341
             + S Q+     V  TN     +E+ TEE
Sbjct: 314 --LSSLQSGNVSAVDLTNHGIQAKEMITEE 341


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  906 bits (2341), Expect = 0.0
 Identities = 572/1313 (43%), Positives = 650/1313 (49%), Gaps = 206/1313 (15%)

Query: 420  GAYGEKGQKGEPAVVEPGMLV----EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            G  GEKG+KG    +   +       G PG  G  G  G  G  GPTG PG+PG  GPPG
Sbjct: 164  GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPG 223

Query: 476  RPGLPGADGLPGPPGTMLML-PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP--- 531
            +PG PG  G PG      M  P   G  GS GPT+  +                 PP   
Sbjct: 224  QPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVE-----------------PPDFC 266

Query: 532  ---GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
               G  G+ G PG VG PG  G KGESG  G +G +G+ G PGP G PG  G PG  G  
Sbjct: 267  LYKGEKGIKGIPGMVGLPGPPGRKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPG-- 323

Query: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP-----------QGPPGPPGDDGMRGEDG 637
             + GE G  GD G  GL G  GD G+RG  GP           +GPPG PG  G  GE G
Sbjct: 324  -LKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG 382

Query: 638  EIGPRGLPGE--------AGPRGLLGPRGTPGAPGQPGMAGV----DGPPGPKGNMGPQG 685
            ++GP G PG         AG  G  GP+G PG PG PG AG+    D  PG  G  G  G
Sbjct: 383  DVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPG 442

Query: 686  EPGPPGQQGNPGPQ------GLPGPQG---PIGPPGEKGPQGKPGLAGL----PGADGPP 732
             PG PG QG PG        G PGPQG    +GPPG +GP+G+ G  GL    PG  GPP
Sbjct: 443  LPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPP 502

Query: 733  GHPGKEGQSGEKGALG------------PPGPQGPIGYPGPRGVKGADGVRG-------- 772
            G PG  G+ G KG LG            PPG +GP G PG  G  G  G +G        
Sbjct: 503  GPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVS 562

Query: 773  -LKGSKGEKGEDG---FPGFKGDMGLKGDRGEVGQIGPRGED-----------GPEGPKG 817
             +KG KGE+G DG   FPG  G  G  G  GE G  GP G+            GP GP G
Sbjct: 563  RVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPG 622

Query: 818  RAGPTGDPGPS--GQAGEKGKLGVPGLPG--------------------YPGRQGPKGST 855
            +AGP G PG    G  GE+G  GVPG PG                    YPGR GP G  
Sbjct: 623  KAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFD 682

Query: 856  GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPR---GSRGARGPTGKPGPKGTSGGD--G 910
            G PG  G  G +GA G++G  G +G+ G  G     G  G RG  G PG  G  G    G
Sbjct: 683  GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG 742

Query: 911  PPGPPGERGPQGPQGPVGFP--GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
            PPGPPG  G  G +G  G P  G  GPPG  G  G+PG  G RG+ G  G  GP G  G 
Sbjct: 743  PPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGF 802

Query: 969  VGPQGPTGETGPIGERGHPGPPGP---------PGEQGLPGAAGKEGAKGDPGPQGISGK 1019
            +G +GP G  G  G  G PGPPG          PG+ GLPG  G  GA G  G  G  G 
Sbjct: 803  LGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGP 862

Query: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPPGPVGS---------PGERGS 1064
             GPAG++G PG  G PGA G PGL G  GP       GPPGP G          PGERG 
Sbjct: 863  PGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK 922

Query: 1065 AGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV---GLPGPAGPAGS 1121
             G  G  G  G PG +G  G  G++G  G KG  GP G +G    +   G PG  GP G 
Sbjct: 923  PGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGD 982

Query: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGPPG----PPGLQGPVGAPGIAGGDGEPGPRGQQG 1177
             G  G++G+ G PG +G +G+ G  GPPG     PG +G  G PG  G  G  G RG  G
Sbjct: 983  DGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIG 1042

Query: 1178 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGD-VGPMGPPGPPGPRGPQGPNGAD 1236
              G  GD+G  G PGPPG  G+ G  GP G KG+     GP GP G PG  G  G  GA 
Sbjct: 1043 FPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGAS 1102

Query: 1237 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
            G QG PG  G  G  G  G PG +G PG PG+ G+ G +G+ GE G+ GP G  G PG  
Sbjct: 1103 GEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIP 1162

Query: 1297 GPPGDDGPKGNPGPVGFPGDPGPPG--------EPGPAGQDGVGGDKGEDGDPGQPG--P 1346
            GPPG  GP G+PG  G  G  G  G        + GP G  G+ G KGE GDPG PG  P
Sbjct: 1163 GPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISP 1222

Query: 1347 PGPSGEAGPPGPPGKRGPPGAAGAEGR-------------QGEKGAKGEAGAEGPPGKTG 1393
            PGP G+ GPPGPPG  GPPG AGA GR             QG  G  G  GA GPPG  G
Sbjct: 1223 PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPG 1282

Query: 1394 PV----GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1449
             V    G  G  G PGP G  G PGP G +G PG  G+DG  GP+G PG  G  G PG  
Sbjct: 1283 SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342

Query: 1450 GEKGHPGLIGLIGP---PGEQGEKGDR----------GLPGTQGSPGAKGDGGIPGPAGP 1496
            GEKG PG  G  GP   PG +GE G            GLPG  G  G +G  G+PG  GP
Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP 1402

Query: 1497 LGP--PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547
             GP   G PGL G +G  G  GS GP G+KGD+G  G PG PGPPG +  P P
Sbjct: 1403 SGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGP 1455



 Score =  896 bits (2315), Expect = 0.0
 Identities = 560/1328 (42%), Positives = 649/1328 (48%), Gaps = 224/1328 (16%)

Query: 424  EKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPG---DPGDRGPPGRPGLP 480
            EKG +G P    P   + GP G  GP G+ G  G++G  GPPG   D GD+GP G PG P
Sbjct: 60   EKGSRGPPGPPGPQGPI-GPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP 118

Query: 481  GADGLPGPPGTM--LMLPFRYGGDGSKG-------------------PTISAQEAQAQAI 519
            G DG+PG PG       P   G +GS+G                   P    ++  +  I
Sbjct: 119  GLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFI 178

Query: 520  LQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPG-- 577
            L   +  ++G  G  GL G PG  G  G +G  G  G+PG  GP G  G PG  G PG  
Sbjct: 179  LGAVK-GIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVG 237

Query: 578  ---KRGRPGADGGRGMPG---------------EPGAKGDRGFDGLPGLPGDKGH----- 614
               + G PG  G +G PG               E G KG  G  GLPG PG KG      
Sbjct: 238  VKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGA 297

Query: 615  RGERGPQGPPGPPGDDGMRGEDGEIGPRG---LPGEAGPRGLLGPRGTPGAPGQPGMAGV 671
            +GE+G  G PGP GD G  G  G  G +G   L G+ G  GL+GP+G PG  G PG  GV
Sbjct: 298  KGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGV 357

Query: 672  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK--------GPQGKPGLA 723
               P P    GP G+PG PG+ G  G  G PGP G +G PGE         GPQG PGL 
Sbjct: 358  LVTP-PLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLP 416

Query: 724  GLPGADGPPGHP----GKEGQSGEKGALGPPGPQG---------PIGYPGPRGVKGADGV 770
            GLPG  G PG P    GK G+ G  G  G PG QG          +G PGP+G+KG  G 
Sbjct: 417  GLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGP 476

Query: 771  RGLKGSKGEKGEDGF-------------PGFKGDMGLKGDRGEVGQIGPRGEDGP---EG 814
             G +G KGEKG +G              PG  G  G KGD G  G +G +G+ GP   EG
Sbjct: 477  PGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEG 536

Query: 815  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874
            P G  G  G  GP G  G KG + V  + G+ G +GP G  GFPG PG++G  G  G  G
Sbjct: 537  PPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKG 596

Query: 875  KPGPRGQR-----------GPTGPRGSRGARGPTGK--PGPKGTSGGDGPPGPPGERGPQ 921
             PGP G             GP GP G  G  GP G   PGP G  G  G PG PG RGP 
Sbjct: 597  DPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPD 656

Query: 922  G--------------------------PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGET- 954
            G                          P GP GFPGP+G PG  G DG  G PG  G   
Sbjct: 657  GLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAE 716

Query: 955  -----GFQGKTGPPGPGGV-----VGPQGPTGETGPIGERGHPGPP-----GPPGEQGLP 999
                 GF+G  G PG GG      VGP GP G  G  G++G PG P     GPPG++GL 
Sbjct: 717  IPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLS 776

Query: 1000 GAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP------QGPP 1053
            G  G +G +GDPG     G +GPAG+ GF G +G  G +G  G  G  GP      +G P
Sbjct: 777  GVPGIKGPRGDPG---CPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAP 833

Query: 1054 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG---EKGPQGPAGRDGVQGPV 1110
            G  G PG  G  G+ G  G  G+PG  GPPGPAG KG PG     G  GP G  G+ GP 
Sbjct: 834  GIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893

Query: 1111 G------LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1164
            G       PGP GP G PG  G  GE G+PG +G  G KGE G  G  GL G  G  G  
Sbjct: 894  GDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAK 953

Query: 1165 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG-- 1222
            G  G PG  G+  +  QKG  G  G PG  G  G +G  G PG +G  G+ G  GPPG  
Sbjct: 954  GAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFH 1013

Query: 1223 --PPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
               PG +G  GP G  GP G  G  G +G  G  G+ GE G+PGPPG +G+ G +G +G 
Sbjct: 1014 RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGN 1073

Query: 1281 KGEA----GPPGAAGPPGAKGPPGDDGPKGNPG------PVGFPGDPGPPGEPGPAG--- 1327
            KG+     GPPG  G PG+ G PG  G  G  G      P G PG PGPPG  GP G   
Sbjct: 1074 KGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPG 1133

Query: 1328 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEG 1387
              G+ G +G+ G+ G PGP G  G+ G PGPPG +GP G+ G  G  G KG KG  GA G
Sbjct: 1134 DHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASG 1193

Query: 1388 -----PPGKTG-----------------PVGPQGPAGKPGPEGLRGIPGPVGEQGL---- 1421
                 PPG  G                 P GP+G  G PGP G  G PGP G  G     
Sbjct: 1194 LHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKD 1253

Query: 1422 ---PGAAGQDGPPGPMGPPGLPGLKGDPGS----KGEKGHPGLIGLIGPPGEQGEKGDRG 1474
               PG  G  GPPGP GP G PG  G PGS    +GE G  GL G  GPPG  G  G +G
Sbjct: 1254 IPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG 1313

Query: 1475 LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG 1534
             PG  G  G KG  G PGP GP G PGPPG          KG  GP G+KG +GLPGP G
Sbjct: 1314 FPGCDGKDGQKGPVGFPGPQGPHGFPGPPG---------EKGLPGPPGRKGPTGLPGPRG 1364

Query: 1535 SPGPPGEV 1542
             PGPP +V
Sbjct: 1365 EPGPPADV 1372



 Score =  722 bits (1864), Expect = 0.0
 Identities = 456/1126 (40%), Positives = 526/1126 (46%), Gaps = 194/1126 (17%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGH-------GAYGEKGQKGEPA----VVEPGMLVE 441
            P   P     PG P         + G        G YGE G  G P     +  PG    
Sbjct: 342  PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401

Query: 442  GPPGPAGPAGIMGPPGLQGPTGPPGDP----GDRGPPGRPGLPGADGLPGPPGTMLM--- 494
            G  GP GP G  G PGL G  G PG P    G  G PG PGLPGA GL G PG+ ++   
Sbjct: 402  GMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCS 461

Query: 495  --------LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGP 546
                    +  + G  G +GP    +  +    L        GPPGP GL GR G  G  
Sbjct: 462  VGNPGPQGIKGKVGPPGGRGP----KGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDL 517

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG------MPGEPGAKGDR 600
            G  G  G  GDPGP G    +GPPG  GK G  G PG  G +G      + G  G +G  
Sbjct: 518  GLPGWLGTKGDPGPPG---AEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPD 574

Query: 601  GFDGLPGLPGDKGHRGERGPQGPPGPPGDD-----GMRGEDGEIGPRGLPGEAGPRGL-- 653
            G  G PG PG  G  G  G +G PGPPGD      G +G  G +GP G  G  GP GL  
Sbjct: 575  GPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGF 634

Query: 654  ---LGPRGTPGAPGQPGMAG--------------------------VDGPPGPKGNMGPQ 684
                G RG PG PG PG+ G                           DGPPGPKG  GPQ
Sbjct: 635  PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQ 694

Query: 685  GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD--GPPGHPGKEGQSG 742
            G PG  G  G+ G  G PG     GPPG +G  G PG  G  G+   GPPG PG  G +G
Sbjct: 695  GAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNG 754

Query: 743  EKGA--------LGPPG------------PQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
            +KG         LGPPG            P+G  G PG  G  G  G  GLKG KG +G 
Sbjct: 755  QKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGH 814

Query: 783  DGFPG------------------------FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 818
             GFPG                        + G  G  G +G+ G +GP G  G +G  G 
Sbjct: 815  AGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL 874

Query: 819  AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG---VAGK 875
             G  G  GP G  G  G  G  GLPG PG +GP+G  GFPGFPG  G+ GA G     G+
Sbjct: 875  PGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGE 934

Query: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGT------SGGDGPPGPPGERGPQGPQGPVGF 929
            PG +G  G  G RG RGA+G  G PG +G        G  G PGPPG+ G  G +G  G 
Sbjct: 935  PGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGT 994

Query: 930  PGPKGPPGPPGKDGLPG-HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPG 988
            PG +G  G PG+ G PG H G+ GE G  G  GPPGP G  G +G  G  G  G++G PG
Sbjct: 995  PGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPG 1054

Query: 989  PPGPPGEQGLPGAAGKEGAKGDP-------GPQGISGKDGPAGLRGFPGERGLPGAQGAP 1041
             PGPPG  G+ GA G +G KGDP       GP+G  G  G  G  G  GE+GLPG QG  
Sbjct: 1055 SPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPR 1114

Query: 1042 GLKGGEGPQGPPGPVGSPGERG---------SAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092
            G  G  GP G  GP G PG+ G           G  GP GL G PG  GPPG  G  G+P
Sbjct: 1115 GSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSP 1174

Query: 1093 GEKGPQGPAGRDGVQGPVGLP--GPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1150
            G  G  G  G+ G +G  GL   GP GP G PG  G++G+ G PG     G +G+ GPPG
Sbjct: 1175 GLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS-PPGPRGKKGPPG 1233

Query: 1151 PPGLQGPVGA-------------PGIAGGDGEPGPRGQQG-------------MFGQKGD 1184
            PPG  GP G              PG  G  G PGP G +G             + G+ GD
Sbjct: 1234 PPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGD 1293

Query: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244
             G  G PGPPGP G  G  G PG  G++G  GP+G PGP GP G  GP G  G  GPPG 
Sbjct: 1294 CGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR 1353

Query: 1245 VGSVGGVGEKGEPGEAGN-------PGPPGEAGVGGPKGERGEKGEAGP--PGAAGPPGA 1295
             G  G  G +GEPG   +       PG PG  G+ GP+G  G  G  GP  PG  G PG 
Sbjct: 1354 KGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGL 1413

Query: 1296 KGPPGDDGPKGNPGPVG---------FPGDPGPPGEPGPAGQDGVG 1332
             G  G DG  G+PGP G         +PG PGPPG  G  G  G G
Sbjct: 1414 DGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFG 1459



 Score =  681 bits (1756), Expect = 0.0
 Identities = 419/959 (43%), Positives = 493/959 (51%), Gaps = 141/959 (14%)

Query: 692  QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPG 751
            ++G+ GP G PGPQGPIGP G  GP G  G  G+ G  GPP            GA G  G
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPP------------GAAGDKG 107

Query: 752  PQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDG 811
             +GP G PG  G+ G  G  G  G +G+ G  G  G +GD G  G RG +G  GP G  G
Sbjct: 108  DKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPG 167

Query: 812  PEGPKGRA----GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA---N 864
             +G KG +    G        G  G++G  G+PGLPG  G  GP G TG+PG PG     
Sbjct: 168  EKGEKGNSVFILGAV-----KGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPP 222

Query: 865  GEKGARGVAGKPGP--RGQRGPTGPRGSRGARGPT------------GKPGPKGTSGGDG 910
            G+ G  G+ G PG   +GQ G  G  G +G+ GPT            G+ G KG  G  G
Sbjct: 223  GQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVG 282

Query: 911  PPGPPGERGPQG--PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
             PGPPG +G  G   +G  G PG  GP G PG  G PG PG +GE G     G PG  G+
Sbjct: 283  LPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGL---VGDPGLFGL 339

Query: 969  VGPQGPTGETGPIGERGHPGPPG-----------PPGEQGLPGAAGKEGAKGDPGPQGIS 1017
            +GP+G  G       RGHPGPPG           PPG+ G PG  G+ G  G PGP G+ 
Sbjct: 340  IGPKGDPGN------RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLL 393

Query: 1018 GKDGPA--GLRGFPGERGLPGAQGAPGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLP 1074
            G+ G A  G+ G PG +G PG  G PG  G  G P   PG  G PG  G  G  G  GLP
Sbjct: 394  GRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLP 453

Query: 1075 GRP------GPQGPPGPAGEKGAPGEKGPQGPAGRDGV----QGPVGLPGPAGPAGSPGE 1124
            G        G  GP G  G+ G PG +GP+G  G +G+     GP+G   P GP G PG 
Sbjct: 454  GSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMG---PPGPPGLPGR 510

Query: 1125 DGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG---MFGQ 1181
             G KG++G PG  G+KGD      PGPPG +GP G PG  G  G PG +G +G   +   
Sbjct: 511  QGSKGDLGLPGWLGTKGD------PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRV 564

Query: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD--GPQ 1239
            KG +G RG  GPPG       PG PG  G +G  G  G PGPPG      P G    GP 
Sbjct: 565  KGHKGERGPDGPPG------FPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPL 618

Query: 1240 GPPGSVGSVG--GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEA-----------GP 1286
            GPPG  G VG  G+G  G PGE G+PG PG  GV GP G +G+KG+            GP
Sbjct: 619  GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678

Query: 1287 PGAAGPPGAKGPPG---------DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1337
            PG  GPPG KG PG          DG KG PG  G    PGPPG  G  G  G GG+KG 
Sbjct: 679  PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS 738

Query: 1338 D--GDPGQPGPPGPSGEAGPPGPP--GKRGPPGAAGAEGRQGEKGAKGEAG---AEGPPG 1390
               G PG PG PG +G+ G PG P  G  GPPG  G  G  G KG +G+ G   AEGP G
Sbjct: 739  SPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAG 798

Query: 1391 KTGPVGPQGPAGKPGPEGLRGIPGPVG---EQGLPGAAGQDGPPGPMGPPGLPGLKGDPG 1447
              G +G +GP G+ G  G  G+PGP G   E+G PG  GQ G PG  G PG PG KG PG
Sbjct: 799  IPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPG 858

Query: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1507
              G  G  G+ GL G PG  G  G  GLPG    PG  GD G+PGP GP GP G PG PG
Sbjct: 859  DVGPPGPAGMKGLPGLPGRPGAHGPPGLPGI---PGPFGDDGLPGPPGPKGPRGLPGFPG 915

Query: 1508 PQGPKGNKGSTGPAGQKGD------SGLP------GPPGSPGPPGEVIQPLPILSSKKT 1554
              G +G  G+ G  G KG+      SGLP      G  G+ GPPG+  + + I+S K T
Sbjct: 916  FPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGE-MAIISQKGT 973



 Score =  637 bits (1642), Expect = 0.0
 Identities = 413/1006 (41%), Positives = 477/1006 (47%), Gaps = 204/1006 (20%)

Query: 390  EDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGP 449
            E  P  PP     PG+P      + S    G  G  G KG+P    PG   EGPPG  G 
Sbjct: 495  EPGPMGPPGP---PGLPGR----QGSKGDLGLPGWLGTKGDPG--PPG--AEGPPGLPGK 543

Query: 450  AGIMGPPGLQG------------------PTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 491
             G  GPPG +G                  P GPPG PG  G  GR G  G  G PGPPG 
Sbjct: 544  HGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGD 603

Query: 492  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGA 551
                    GG G  GP     +A     +    +   GPPG  G  G PG  G  G  G 
Sbjct: 604  HE--DATPGGKGFPGPLGPPGKAGP---VGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658

Query: 552  KGESGD--------PGPQGPRGVQGPPGPTGKPGKRGRPG---ADGGRGMPGEPGAKGDR 600
            KG+ GD        PG  GP G  GPPGP G PG +G PG   +DG +G PG PG     
Sbjct: 659  KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIP 718

Query: 601  GFDGLPGLPGDKGHRGERG--PQGPPGPPGDDGMRGEDG--------EIGPRGLPGEAGP 650
            G  G  G  GD G  GE+G  P GPPGPPG  G+ G+ G         +GP G  G +G 
Sbjct: 719  GPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGV 778

Query: 651  RGLLGPRGTPGAPGQ------PGMAGVDGPPGPKGNMGPQGEPGPPGQQ------GNPGP 698
             G+ GPRG PG PG       PG  G+ GP G +G+ G  G PGPPG        G PG 
Sbjct: 779  PGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQ 838

Query: 699  QGLPG------------PQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGA 746
             GLPG              G +GPPG  G +G PGL G PGA GPPG PG  G  G+ G 
Sbjct: 839  PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGL 898

Query: 747  LGPPGPQGP------IGYPGPRGVKGADGVRGLKGSKGEK-------------------- 780
             GPPGP+GP       G+PG RG  GA+G  G KG  GEK                    
Sbjct: 899  PGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGP 958

Query: 781  ----------------------GEDGFPGFKGDM---GLKGDRGEVGQIGPRG-EDGPEG 814
                                  G+DGFPG +GD    G++G RGE G+ GP G   G  G
Sbjct: 959  PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG 1018

Query: 815  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA- 873
             KG+ GP G PGP G  G +G +G PGLPG  G  G  G  GF G  GA G KG +G   
Sbjct: 1019 EKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA 1078

Query: 874  ---GKPGPRGQR---------GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER--- 918
               G PGP+G+          G +G +G  G +GP G PG  G  G  GPPG PG+    
Sbjct: 1079 SHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMP 1138

Query: 919  ------------GPQGPQGPVGFPGP---KGPPGPPGKDGLPGHPGQRGETGFQG--KTG 961
                        GP+G QG  G PGP   KGP G PG +GL G  GQ+G  G  G    G
Sbjct: 1139 GLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVG 1198

Query: 962  PPGPGGVVGPQGPTGETG-----PIGERGHPGPPGPPGEQGLPGAAGKEGAK----GDPG 1012
            PPGP G+ G +G  G+ G     P G RG  GPPGPPG  G PG AG  G       DPG
Sbjct: 1199 PPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG 1258

Query: 1013 PQGISGKDGPAGLRGFPGERGLPGA----QGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1068
            P G  G  GP G RG PG  GLPG+    +G PG  G  GP GPPGP G PG +G  G  
Sbjct: 1259 PPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCD 1318

Query: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128
            G  G  G  G  GP GP G  G PGEKG  GP GR   +GP GLPGP G  G P +  D 
Sbjct: 1319 GKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR---KGPTGLPGPRGEPGPPADVDDC 1375

Query: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188
              I  PG  G+ G +G  G  G PG++GP G          PG +G+ G+ G++G +G  
Sbjct: 1376 PRI--PGLPGAPGMRGPEGAMGLPGMRGPSG----------PGCKGEPGLDGRRGVDGVP 1423

Query: 1189 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1234
            G PGPPG             KG+ G+ G  G PGPPGP G  GP G
Sbjct: 1424 GSPGPPG------------RKGDTGEDGYPGGPGPPGPIGDPGPKG 1457



 Score =  515 bits (1326), Expect = e-145
 Identities = 333/782 (42%), Positives = 371/782 (47%), Gaps = 143/782 (18%)

Query: 376  GDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAVV 434
            GD+G+  F   K     P  PP     PGV  +  I      GH G  G++G  G P + 
Sbjct: 725  GDMGDPGFGGEKG--SSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIK 782

Query: 435  EPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD---PGDRGPPGR------PGLPGADGL 485
             P     G PG  GPAGI G  GL+GP G  G    PG  GPPG       PG+PG  GL
Sbjct: 783  GPRG-DPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGL 841

Query: 486  PGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGG 545
            PG PG+    P   GG G  G                      GPPGP G+ G PG  G 
Sbjct: 842  PGYPGS----PGAPGGKGQPGDV--------------------GPPGPAGMKGLPGLPGR 877

Query: 546  PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---PGAKGDRGF 602
            PG+ G  G  G PGP G  G+ GPPGP G  G  G PG  G RG PG    PGAKG+ G 
Sbjct: 878  PGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE 937

Query: 603  DGLPGLPGDKGHRGERGPQGPPG------------------PPGDDGMRGEDGEIGPRGL 644
             G+ GLPGD+G RG +G  GPPG                  PPGDDG  GE G+ G  G+
Sbjct: 938  KGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGM 997

Query: 645  PGEAGPRGLLGP----RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 700
             G  G  G  GP    RG PG  GQPG  G  GPPG  G  G  G PG PG QG PG  G
Sbjct: 998  QGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG 1057

Query: 701  LPG----------------PQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
             PG                P    GPPG KG  G PG  G  GA G  G PG +G  G  
Sbjct: 1058 PPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSP 1117

Query: 745  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
            G  GPPG  GP G PG  G+ G  G  G  G  G +G  G PG  G  G+KG  G  G  
Sbjct: 1118 GRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLN 1177

Query: 805  GPRGEDGPEGPKGRAG--PTGDPGPSGQAGEKGKLGVPGLPGY--PGRQGPKGSTGFPGF 860
            G  G  G +G KG +G    G PGP G  G KG+ G PG PG   PG +G KG  G PG 
Sbjct: 1178 GLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGS 1237

Query: 861  PGANGEKGARGVAGK----PGPRGQRGPTGPRGSRGARGPTGKPGP----KGTSGGDGPP 912
             G  G  GA G A K    PGP G +GP GP G RGA GP G PG     +G  G  G P
Sbjct: 1238 SGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP 1297

Query: 913  GPPGERGPQGP---------------QGPVGFPGPKGP---PGPPGKDGLPGHPGQRGET 954
            GPPG  GP GP               +GPVGFPGP+GP   PGPPG+ GLPG PG++G T
Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPT 1357

Query: 955  GFQGKTGPPGPG-------------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001
            G  G  G PGP              G  G +GP G  G  G RG P  PG  GE GL G 
Sbjct: 1358 GLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRG-PSGPGCKGEPGLDGR 1416

Query: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1061
             G +G  G PGP               PG +G  G  G PG     GP GPPGP+G PG 
Sbjct: 1417 RGVDGVPGSPGP---------------PGRKGDTGEDGYPG-----GP-GPPGPIGDPGP 1455

Query: 1062 RG 1063
            +G
Sbjct: 1456 KG 1457



 Score =  244 bits (624), Expect = 4e-64
 Identities = 148/322 (45%), Positives = 165/322 (51%), Gaps = 35/322 (10%)

Query: 1251 VGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP 1310
            V EKG  G  G PGP G  G  G  G  G  GE G  G  GPPGA G  GD GP G PG 
Sbjct: 58   VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGF 117

Query: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA-- 1368
             G  G PG PG PGP G+ G+ G  G  GDPG PG  G  G  GP G PG++G  G +  
Sbjct: 118  PGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVF 177

Query: 1369 --GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG 1426
              GA   +G +G +G+ G  G PG  G  GP GP G PG  GL G PG  G  GL G  G
Sbjct: 178  ILGAV--KGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG 235

Query: 1427 QDGPPGPMGPPGLPGLKGDP---------------GSKGEKGHPGLIGLIGPPGE----- 1466
              G  G MG PG  G +G P               G KG KG PG++GL GPPG      
Sbjct: 236  V-GVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG 294

Query: 1467 ---QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP---GLPGPQGPKGNKGSTGP 1520
               +GEKG  G PG +G PG+ G  G PG  G LG  G P   GL GP+G  GN+G  GP
Sbjct: 295  IGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354

Query: 1521 AGQKGDSGLP--GPPGSPGPPG 1540
             G      LP  GPPG PG PG
Sbjct: 355  PGVLVTPPLPLKGPPGDPGFPG 376



 Score =  128 bits (321), Expect = 6e-29
 Identities = 89/220 (40%), Positives = 97/220 (44%), Gaps = 25/220 (11%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452
            P  P      PG+P   D+           GE G  G P    P     GPPGP G  G 
Sbjct: 1268 PDGPRGAPGPPGLPGSVDLLR---------GEPGDCGLPGPPGP----PGPPGPPGYKGF 1314

Query: 453  MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LMLPFRYGGDGSKGPTIS 510
             G  G  G  GP G PG +GP G PG PG  GLPGPPG      LP   G  G  GP   
Sbjct: 1315 PGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLP---GPRGEPGPPAD 1371

Query: 511  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570
              +      L  A   +RGP G MGL G  GP G     G KGE G  G +G  GV G P
Sbjct: 1372 VDDCPRIPGLPGAP-GMRGPEGAMGLPGMRGPSG----PGCKGEPGLDGRRGVDGVPGSP 1426

Query: 571  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 610
            GP G+ G  G  G  GG G PG  G  G +GF   PG  G
Sbjct: 1427 GPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFG--PGYLG 1464



 Score =  104 bits (260), Expect = 7e-22
 Identities = 63/151 (41%), Positives = 77/151 (50%), Gaps = 21/151 (13%)

Query: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP 1476
            G +G PG  G  GP GP+G PG  GL G+ G +G++G         PPG  G+KGD+G  
Sbjct: 62   GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG---------PPGAAGDKGDKGPT 112

Query: 1477 GTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536
            G  G PG  G   IPG     GPPGP G PG  G  G++G  G  G +G  G  GP G P
Sbjct: 113  GVPGFPGLDG---IPGHP---GPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHP 166

Query: 1537 GPPGEVIQPLPILSSKKTRRHTEGMQADADD 1567
            G  GE    + IL + K      G+Q D  D
Sbjct: 167  GEKGEKGNSVFILGAVK------GIQGDRGD 191



 Score = 36.2 bits (82), Expect = 0.30
 Identities = 21/46 (45%), Positives = 24/46 (52%), Gaps = 1/46 (2%)

Query: 1523 QKGDSGLPGPPGSPGPPGEVIQPLPI-LSSKKTRRHTEGMQADADD 1567
            +KG  G PGPPG  GP G +  P PI LS +K  R   G    A D
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGD 105


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 476  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 534
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 535  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 584
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 641
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 642  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 694
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 695  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 747
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 748  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 796
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 797  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 840
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 841  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 883
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 884  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 934
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 994
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 995  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1054
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1055 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1113 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1160
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1217
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1275
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1329
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1330 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1373
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1431
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1432 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1480
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1531
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1532 PPGSPGPPGEV 1542
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  833 bits (2153), Expect = 0.0
 Identities = 510/1180 (43%), Positives = 594/1180 (50%), Gaps = 120/1180 (10%)

Query: 397  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 443
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 444  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 497
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 498  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 556
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 557  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 613  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 669  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 723
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 724  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 837
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 895
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 896  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 1014 QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1126
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1127 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1183 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1299
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1300 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479
             LPG+      PGP G PG PG++G+PG              GPPG  G  G RG PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPP------------GPPGNLGPCGPRGKPGKD 1396

Query: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG 1519
            G PG                      PGP G KGNKGS G
Sbjct: 1397 GKPGT---------------------PGPAGEKGNKGSKG 1415



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 600
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 601  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 658  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 707  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 756
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 757  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 803  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 845
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 846  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 896
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 897  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 918
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 919  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 1023
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 1024 GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1077 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1120
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1121 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1166
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1167 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1221
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1278
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1279 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1332
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1333 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1362
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1363 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1415 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1463
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1464 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1512
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPG 1537
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  780 bits (2015), Expect = 0.0
 Identities = 479/1110 (43%), Positives = 559/1110 (50%), Gaps = 113/1110 (10%)

Query: 365  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 413
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 414  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 467
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 468  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 521
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 522  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 577
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 578  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 629
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 630  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 746  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 804  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 856
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 857  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 911  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 961
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1078
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1079 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1129
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1130 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1186 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1235
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1236 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1295
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1296 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
             GP G PGK G PG  G  G +G KG+KGE
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 712
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 713  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 766
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 767  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 813
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 814  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 926
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 927  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 977
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 978  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 1020
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1131
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1132 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1242 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1291
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1292 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1334
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1443
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1444 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1487
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1488 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1543 IQPLP 1547
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 824  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 871
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 907
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 908  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 945
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 946  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 994
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 995  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1053 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1092
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1093 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1131
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1132 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1239
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1240 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1291 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1344 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1396
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1397 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1446
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1447 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1494
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1554
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1555 RRHTEGMQADADD 1567
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  494 bits (1272), Expect = e-139
 Identities = 309/729 (42%), Positives = 368/729 (50%), Gaps = 86/729 (11%)

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKG---------QKGEPAVVEPGML----VEG 442
            PP  +   G P     T+ S+   G  GE G          KGEPAV  PG        G
Sbjct: 704  PPGPKGDQGFPG----TKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 443  PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD 502
              G +G  G +G PGL G  G PG+ G  GP G PG PG  G  GPPG  +      G  
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIE-----GPR 814

Query: 503  GSKG-PTISAQEAQAQAILQQARIALRGPPGPMGL--TGRPGPVGGPGSSGAKGESGDPG 559
            G++G P ++  + Q     ++ +   +G PG  GL  +G PG  G PG  G +GE G  G
Sbjct: 815  GAQGLPGLNGLKGQQG---RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 560  PQG---PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 616
             +G     G+ GPPG  G  G  G PGA G  G PG PG  G RG    PG+PG KG RG
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS---PGIPGVKGQRG 928

Query: 617  ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676
              G +G  G  G+ G       IG +G PG  G  G  G +G  G PG PG+ G+ G PG
Sbjct: 929  TPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG 988

Query: 677  PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ---------GKPGLAGL-- 725
            P G  GP+G+ G  G  G PG +G+PG  G +G PG KG +         G+PGL G+  
Sbjct: 989  PAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048

Query: 726  ---------------PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGV 770
                           PG  GP G PG  G  G+KG +G PGP G +G  GP G  G+ G 
Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108

Query: 771  RGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ 830
             GL G  G  G+ GF G KG +G  G RG  G  G  G  GP G +G  G  G PGP+G+
Sbjct: 1109 PGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE 1168

Query: 831  AGEKGKL-GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG 889
             GE G L   PG  G PG QG KG  G PGFPG  G KGA G AG  GP G  G  GP G
Sbjct: 1169 KGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPG 1228

Query: 890  SRGA-----RGPTGKPGPKGTSGGDGPPGPPGER--GPQGPQGPVGFPGPKGPP------ 936
              GA      G  G PG +G+ G  GPPGPPG    G +G +G +G PGPKGPP      
Sbjct: 1229 LPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDM 1288

Query: 937  GPPGK---DGLPGHPGQRGETGFQ------GKTGPPGPGGVVGPQGPTGETGPIGERGHP 987
            GPPG+    G PG PG RG+ GFQ      G+ G PG  G +GP GP G  GP G RG P
Sbjct: 1289 GPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP 1348

Query: 988  GP---PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLK 1044
            G       PG  G PG  G+ G +G+PGP G  G  GP G RG PG+ G PG  G  G K
Sbjct: 1349 GTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK 1408

Query: 1045 GGEGPQGPP 1053
            G +G +G P
Sbjct: 1409 GNKGSKGEP 1417



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1061 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1112 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1167 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1216
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1217 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1269 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1308
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1309 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1353
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1354 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1393
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1449
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1507
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1508 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1540
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  261 bits (668), Expect = 3e-69
 Identities = 168/400 (42%), Positives = 188/400 (47%), Gaps = 54/400 (13%)

Query: 374  VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAV 433
            + GD GE  + E          PP     PG+P             G  G+KG+ G+P  
Sbjct: 1049 LQGDKGEPGYSEGTR-----PGPPGPTGDPGLP-------------GDMGKKGEMGQPG- 1089

Query: 434  VEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRG------PPGRPGLPGADGLPG 487
              PG L  GP GP G  G  G PGL G  GP GD G +G      PPG  G PG  G PG
Sbjct: 1090 -PPGHL--GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPG 1146

Query: 488  PPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPG 547
             PG M +   + G DG  GP     E      L +A    RG PG  G  G  G  G PG
Sbjct: 1147 SPGPMGIRGDQ-GRDGIPGPAGEKGETG----LLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 548  SSGAKGESGDPGPQGPRGVQGPPGPTGKPG-----KRGRPGADGGRGMPGEPGAKGDRGF 602
              G KG  GD GP+GP G++G PGP G PG     + G  G  G RG PG PG  G  G 
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 603  DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA 662
              + G+ GDKG  G  GP+GPPG  GD G  G  G  G  GLPG  G  G  G  G  G 
Sbjct: 1262 HVI-GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGE 1320

Query: 663  PGQPGMAGVDGPPGPKGNMGPQG---------------EPGPPGQQGNPGPQGLPGPQGP 707
             G PG  G  GPPGP G  GP G                PGPPG  G PG QG PGP GP
Sbjct: 1321 KGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGP 1380

Query: 708  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747
             G  G  GP+GKPG  G PG  GP G  G +G  GE  +L
Sbjct: 1381 PGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESL 1420



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1426 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1469
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1470 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1521
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1522 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1548
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1549 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1582
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 476  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 534
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 535  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 584
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 641
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 642  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 694
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 695  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 747
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 748  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 796
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 797  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 840
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 841  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 883
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 884  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 934
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 994
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 995  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1054
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1055 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1113 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1160
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1217
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1275
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1329
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1330 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1373
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1431
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1432 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1480
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1531
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1532 PPGSPGPPGEV 1542
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 397  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 443
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 444  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 497
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 498  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 556
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 557  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 613  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 669  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 723
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 724  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 837
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 895
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 896  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 1014 QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1126
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1127 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1183 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1299
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1300 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1517
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 649  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 708
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 709  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 758
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 759  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 802
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 803  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 847
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 848  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 908  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 963  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1070
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1071 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1123
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1124 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1170
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1228
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1229 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1281 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1337
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1338 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1430
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1431 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1483 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1529
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1530 ---PGPPGSPGPPG 1540
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 600
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 601  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 658  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 707  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 756
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 757  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 803  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 845
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 846  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 896
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 897  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 918
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 919  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 1023
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 1024 GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1077 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1120
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1121 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1166
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1167 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1221
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1278
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1279 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1332
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1333 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1362
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1363 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1415 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1463
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1464 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1512
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPG 1537
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 365  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 413
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 414  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 467
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 468  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 521
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 522  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 577
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 578  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 629
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 630  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 746  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 804  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 856
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 857  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 911  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 961
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1078
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1079 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1129
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1130 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1186 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1235
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1236 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1295
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1296 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1411
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 712
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 713  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 766
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 767  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 813
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 814  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 926
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 927  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 977
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 978  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 1020
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1131
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1132 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1242 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1291
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1292 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1334
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1443
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1444 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1487
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1488 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1543 IQPLP 1547
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 824  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 871
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 907
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 908  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 945
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 946  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 994
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 995  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1053 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1092
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1093 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1131
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1132 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1239
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1240 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1291 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1344 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1396
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1397 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1446
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1447 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1494
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1554
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1555 RRHTEGMQADADD 1567
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1061 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1112 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1167 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1216
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1217 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1269 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1308
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1309 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1353
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1354 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1393
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1449
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1507
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1508 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1540
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 420  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 475  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 529
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 530  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 571
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 572  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 632  MRGEDGEIGPRGLPGEAGPRGLLGPR 657
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1426 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1469
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1470 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1521
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1522 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1548
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1549 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1582
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 456  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 572
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 476  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 534
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 535  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 584
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 641
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 642  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 694
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 695  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 747
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 748  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 796
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 797  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 840
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 841  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 883
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 884  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 934
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 994
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 995  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1054
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1055 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1113 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1160
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1217
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1275
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1329
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1330 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1373
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1431
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1432 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1480
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1531
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1532 PPGSPGPPGEV 1542
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 397  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 443
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 444  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 497
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 498  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 556
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 557  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 613  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 669  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 723
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 724  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 837
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 895
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 896  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 1014 QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1126
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1127 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1183 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1299
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1300 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1517
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 649  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 708
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 709  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 758
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 759  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 802
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 803  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 847
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 848  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 908  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 963  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1070
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1071 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1123
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1124 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1170
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1228
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1229 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1281 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1337
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1338 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1430
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1431 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1483 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1529
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1530 ---PGPPGSPGPPG 1540
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 600
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 601  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 658  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 707  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 756
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 757  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 803  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 845
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 846  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 896
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 897  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 918
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 919  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 1023
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 1024 GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1077 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1120
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1121 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1166
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1167 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1221
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1278
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1279 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1332
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1333 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1362
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1363 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1415 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1463
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1464 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1512
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPG 1537
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 365  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 413
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 414  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 467
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 468  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 521
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 522  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 577
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 578  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 629
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 630  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 746  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 804  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 856
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 857  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 911  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 961
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1078
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1079 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1129
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1130 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1186 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1235
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1236 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1295
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1296 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1411
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 712
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 713  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 766
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 767  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 813
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 814  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 926
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 927  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 977
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 978  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 1020
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1131
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1132 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1242 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1291
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1292 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1334
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1443
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1444 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1487
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1488 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1543 IQPLP 1547
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 824  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 871
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 907
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 908  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 945
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 946  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 994
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 995  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1053 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1092
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1093 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1131
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1132 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1239
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1240 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1291 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1344 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1396
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1397 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1446
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1447 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1494
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1554
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1555 RRHTEGMQADADD 1567
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1061 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1112 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1167 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1216
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1217 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1269 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1308
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1309 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1353
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1354 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1393
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1449
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1507
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1508 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1540
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 420  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 475  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 529
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 530  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 571
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 572  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 632  MRGEDGEIGPRGLPGEAGPRGLLGPR 657
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1426 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1469
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1470 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1521
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1522 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1548
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1549 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1582
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 456  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 572
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  902 bits (2331), Expect = 0.0
 Identities = 565/1271 (44%), Positives = 646/1271 (50%), Gaps = 182/1271 (14%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVE----GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            GA G KGQKG PA  E   L      G PG  GP G+ GPPG  GP GPPG      PPG
Sbjct: 148  GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPG------PPG 201

Query: 476  RPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQEAQAQAILQQARIALRGPPGPM 534
              G PGA G  GP G M      + G+ G KG                    L GPPGP 
Sbjct: 202  FFGFPGAMGPRGPKGHMGERVIGHKGERGVKG--------------------LTGPPGPP 241

Query: 535  G-----LTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP-----GPTGKPGKRGRPGA 584
            G     LTG        G  G KG  G+PGP GP G+ G       G  G PG +G+PG 
Sbjct: 242  GTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGK 301

Query: 585  DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP---GDDGMRGEDGEIGP 641
            DG  G PG  G KG+RGF GL G  G KG +G+ GP G  GP         +G++G  GP
Sbjct: 302  DGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGP 361

Query: 642  RGLPGEAGPRGLLGPRGTPGAPG--QPGMAGVDGPPGPKGNMGPQGEPGP-----PGQQG 694
             G  G  GP+G  GP G PG+PG  +PG+ G  G PG KG+ G +G PG      PG  G
Sbjct: 362  PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 695  NPGPQGLPGPQGPIGPPGE----KGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL--- 747
              G  GLPG  GP GPPG+    KGP   PG  GLPG  G PG PG +G  GE G L   
Sbjct: 422  CAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQ 478

Query: 748  -----GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGF------KGDMGLKG 796
                 GPPG  G  G  G +G+ G  G  GLKGS G  G  G PGF      +GD GLKG
Sbjct: 479  CPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG 538

Query: 797  DRGEV----GQIGPRGEDGPEGPKGRAGPTGDPG---------PSGQ---AGEKGKLGVP 840
            ++GE     GQ+G  G+ G  G  GR G  G PG         P G+   +GEKG  G P
Sbjct: 539  EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP 598

Query: 841  GLPGYPGRQGPKGSTGFPGF-----PGANGEKGARGVAGKPGPRGQRG------------ 883
            G PG PG  GP G  G PG+     PG  G +G  G  G PG  G RG            
Sbjct: 599  GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 884  -PTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG--------PQGPQGPVGFPGPKG 934
             P GP G  G +GP G PG  G  G  G PGP GE G        P GP+G  GFPG KG
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPG 994
              G PGK G PG PG+ G  G +G+     PGG  G  G  GE G  GE G  G PG PG
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP-GTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 995  EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG 1054
              G PG  G +G +GDPG  G  G+ GP G R   G RG  G  G  GLKG +G +G  G
Sbjct: 778  LPGTPGNEGLDGPRGDPGQPGPPGEQGPPG-RCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836

Query: 1055 PVGSPGERG--SAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL 1112
            P G PG  G   +G  G  G PG PG QG  GP G++G PG  G  GP G DGV G +G 
Sbjct: 837  PKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGF 896

Query: 1113 PGPAGPAGSPGEDGDKGEIGEPG------QKGSKGDKGENGPPGPPG------LQGPVGA 1160
            PG  GP G PG  G  G+ G PG      Q+G+ G KGE G  G PG      + G  G 
Sbjct: 897  PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 1161 PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP---PGPIGLQGLPGPPGEKGENGDVGP 1217
            PG+ G  G PG +G +G+ G  G +G +G PGP   PGP G  G  G PGE G  G  G 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG--EAGNPGPPGEAGVGGPK 1275
            MG  G PG +G +G  G  G  G PG  G  G  G+KGEPG  E   PGPPG  G  G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE------PGPAGQD 1329
            G+ G+KGE G PG   PPG  GP G +G  G+PG  G PG PGP G+       G  G  
Sbjct: 1077 GDMGKKGEMGQPG---PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPP 1133

Query: 1330 GVGGDKGEDGDPGQPGP------------PGPSGEAGPPG----PPGKRGPPGAAGAEGR 1373
            G+ G  G  G PG PGP            PGP+GE G  G    PPG RG PGA GA+G 
Sbjct: 1134 GIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGD 1193

Query: 1374 QGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG--IPGPVGEQGLPGAAGQDGPP 1431
            +G  G  G  G +G  G  GP GP G  G PGP GL G  IPG  G +G PG+ G  G P
Sbjct: 1194 RGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAP 1253

Query: 1432 GPMGPPG--LPGLKGDPGSKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGT------QG 1480
            GP GPPG  + G+KGD GS G    KG PG  G +GPPG  G  G  GLPG       QG
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN---------KGSTGPAGQKGDSGLPG 1531
             PG KG+ G PG  G +GPPGP G  GP G +G+          GS GP G  G+ G+ G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 1532 PPGSPGPPGEV 1542
             PG PGPPG +
Sbjct: 1374 EPGPPGPPGNL 1384



 Score =  852 bits (2200), Expect = 0.0
 Identities = 516/1178 (43%), Positives = 606/1178 (51%), Gaps = 96/1178 (8%)

Query: 397  PNEEFGPGVPAETDITETS-----INGHGAYGEKGQKGEPAVVEPGMLV--------EGP 443
            P ++  PG P    +         +   G  G+KG  G P    P            EG 
Sbjct: 299  PGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358

Query: 444  PGPAGPAGIMGPPGLQGPTGPPGDPGD-----RGPPGRPGLPGADGLPGPPGTMLM-LPF 497
            PGP GP G  GP G  GP G PG PG      RG PG PGL G+ G  G PG   M  P 
Sbjct: 359  PGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 498  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG- 556
              G  GS G   S         +    +  +GPPG  GL G  G  G PG  G KGE G 
Sbjct: 419  SPGCAGSPGLPGSPGPPGPPGDI----VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474

Query: 557  ----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612
                 P   GP G+ G PG  G  G  GR GA G +G PG PG  G  GF G PG  GD 
Sbjct: 475  LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534

Query: 613  GHRGERG----PQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668
            G +GE+G    P+G  G PGD G+RG+ G  G  G+PG  G +GL GP+G     G+ G 
Sbjct: 535  GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594

Query: 669  AGVDGPPGPKGNMGPQGEPGPPGQ--QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA--- 723
             G  G PG  G+ GP G  GPPG   QG PG QG  G  G  GPPGE GP+G+  ++   
Sbjct: 595  QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654

Query: 724  -GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGE 782
             G PG  GPPGHPG +G  G  G+LG  G  G    PGP G  G  G+ G  G  G KG+
Sbjct: 655  PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---LPGPDGEPGIPGI-GFPGPPGPKGD 710

Query: 783  DGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK-----GRAGPTGDPGPSGQAGEKGKL 837
             GFPG KG +G  G  GE G  G  G  G +G       G  G  G PG  G +GE G++
Sbjct: 711  QGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEI 770

Query: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK--PGPRGQRGPTGPRGSRGARG 895
            G+PGLPG PG  G +G  G  G PG  G  G +G  G+   GPRG +G  G  G +G +G
Sbjct: 771  GLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQG 830

Query: 896  PTGKPGPKGTSGGDGPPGPPG--ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 953
              GK GPKG       PG PG    G  G  G  G PG +G  GP G+ G PG+PG  G 
Sbjct: 831  RRGKTGPKGD------PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884

Query: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGP 1013
             G  G  G  G  G +GP GP G  G  G+RG PG PG  G++G PGA G++G KG+PGP
Sbjct: 885  PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944

Query: 1014 QGIS---GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070
              IS   G  G  GL+GF G  G  G +G PG+ G +G +G PGP G PG RG  G+ G 
Sbjct: 945  SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN 1004

Query: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG---- 1126
               PG PG +G PG  G  G PG KG +G  G  G  G  GLPG  G  G  GE G    
Sbjct: 1005 ---PGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061

Query: 1127 ----DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182
                  G  G+PG  G  G KGE G PGPPG  GP G  G  G  G PG  G+ G  G  
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121

Query: 1183 GDEGARGFPGPPG---PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1239
            G +G +G  GPPG   P GL G PG PG  G  GD G  G PGP G +G  G   A  P 
Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA--PP 1179

Query: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPP 1299
            GP G+ G+ G  G++G PG  G PG  G  G  GP+G  G +G  GPPG    PGA   P
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL---PGAI-IP 1235

Query: 1300 GDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359
            G  G +G PG  G PG PGPPG PG +   G+ GDKG  G PG  GPPG +G+ GPPG  
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG-SHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL 1294

Query: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419
            G  G PG  G  G  G +G  G  G +G PG  G +GP GP G  GP G+RG PG +   
Sbjct: 1295 GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII 1354

Query: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479
             LPG+      PGP G PG PG++G+PG  G    PG +G  GP G+ G+ G  G PG  
Sbjct: 1355 SLPGS------PGPPGTPGEPGMQGEPGPPGP---PGNLGPCGPRGKPGKDGKPGTPGPA 1405

Query: 1480 GSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGS 1517
            G  G KG  G PGPA      G  GLPG +G +G+ GS
Sbjct: 1406 GEKGNKGSKGEPGPA------GSDGLPGLKGKRGDSGS 1437



 Score =  816 bits (2109), Expect = 0.0
 Identities = 502/1154 (43%), Positives = 578/1154 (50%), Gaps = 149/1154 (12%)

Query: 529  GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588
            G  G  G  G PGP G PG  G  G  G PGPQGP+G  G PG TG  G RG  G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648
            G PG PG  G+ G  GL G+PG  G +GE+G  G PG  G  G+ G  G  G +G P + 
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 649  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 708
                L   +G PG PG PG  G+ GPPG  G +GP   PGPPG  G PG  G  GP+G +
Sbjct: 163  EDIEL-DAKGDPGLPGAPGPQGLPGPPGFPGPVGP---PGPPGFFGFPGAMGPRGPKGHM 218

Query: 709  GPP--GEKGPQGKPGLAGLPGADG--------PPGHPGKEGQSGEKGALGPPGPQGPIGY 758
            G    G KG +G  GL G PG  G        P      +G+ G+KGA+G PGP GP G 
Sbjct: 219  GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGL 278

Query: 759  PGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG-- 802
            PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G  
Sbjct: 279  PGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPP 338

Query: 803  -------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGYPG 847
                         + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+PG
Sbjct: 339  GFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPG 398

Query: 848  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907
             +G KG  G PG   A G  G+ G AG PG  G  GP GP G    R   G PG  G  G
Sbjct: 399  LKGSKGERGRPG-KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFR--KGPPGDHGLPG 455

Query: 908  GDGPPGPPGERGPQGPQGPVG-----FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 962
              G PG PG  GP+G  G +       PGP G PG PG  G+ G PG++G  G +G  G 
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 963  PG----PG--GVVGPQGPTGETGPIGE----RGHPGPPGPPGEQGLPGAAGKEGAKGDPG 1012
            PG    PG  G  G QG  G  G  GE     G  G PG PG +G PG  G +G  G PG
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 1013 PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG--PVGSPGERGSAGTAGP 1070
             +G+ G  G   L G  G++G PG  G+PG  G  GP GPPG  P G PG +G+ G  G 
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 1071 IGLPGRPGPQGP-------PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPG 1123
             G PG  GP+G        PGP G  G PG  GPQGP G  G  G  G PG  GP G PG
Sbjct: 636  PGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG 695

Query: 1124 --------EDGDKGEIGEPGQKGS---KGDKGENGPPGPPGLQGPVGAPGIA--GGDGEP 1170
                      G KG+ G PG KGS    G  GE G PG PGL G  G P +A  GG G P
Sbjct: 696  IPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTP 755

Query: 1171 GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP--PGPRG 1228
            G  G++G  G+ G+ G  G PG PG  G +GL GP G+ G+ G  G  GPPG    GPRG
Sbjct: 756  GFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 1229 PQGPNGADGPQGPPGSVGSVG--------GVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280
             QG  G +G +G  G  G  G        G+   G PGE G+PG PG  G  GP G+RG 
Sbjct: 816  AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGY 875

Query: 1281 KGEAG---PPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1337
             G  G   PPG  G  G  G PG  GP G PG  G PG  G PG PG  GQ G  G KGE
Sbjct: 876  PGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGE 935

Query: 1338 DGDPGQPGPPGPS---GEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
             GD G PGP   S   G+ G PG  G  G PG  G  G  G  G KG  G  GP G  GP
Sbjct: 936  QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGP 995

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP------------------------ 1430
             G  G  G PG  GLRGIPG +G  G+PG+ G+ G                         
Sbjct: 996  RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055

Query: 1431 --------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482
                    PGP GP G PGL GD G KGE G PG  G +GP G +G  G  G PG  G P
Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115

Query: 1483 GAKGDGGIPGPAGPLGPP---GPPGL------PGPQGPKGNKGS---TGPAGQKGDSGL- 1529
            G  GD G  G  G LGPP   GPPGL      PGP G +G++G     GPAG+KG++GL 
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175

Query: 1530 ---PGPPGSPGPPG 1540
               PGP G+PG  G
Sbjct: 1176 RAPPGPRGNPGAQG 1189



 Score =  800 bits (2067), Expect = 0.0
 Identities = 505/1225 (41%), Positives = 575/1225 (46%), Gaps = 241/1225 (19%)

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDR------ 600
            G+ G KGE G PGP G       PG  G  G  G PG  G +G PG PG  G +      
Sbjct: 43   GAKGEKGEKGFPGPPGS------PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 601  ---GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR 657
               GF G PGLPG  G+ G  G  G PG  G  G +G  G  G  G PG  G  GL G +
Sbjct: 97   GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 658  GTP-----------GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706
            G P           G PG PG  G  G PGP G  GP G PGPPG  G PG  G  GP+G
Sbjct: 157  GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 707  PIGPP--GEKGPQGKPGLAGLPG--------ADGPPGHPGKEGQSGEKGALGPPGPQGPI 756
             +G    G KG +G  GL G PG          GP      +G+ G+KGA+G PGP GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 757  GYPGP--------------RGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            G PG               +G  G DGV G  GS+G KG  GFPG  G+ G+KG +G++G
Sbjct: 277  GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 803  ---------------QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG--KLGVPGLPGY 845
                           + G  G  GP GP+G  GP G  GP G  G  G  + G+ G PG+
Sbjct: 337  PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 846  PGRQGPKGSTGFP-----GFPGANGEKGARGVAGKPGPRGQRGP----TGPRGSRGARGP 896
            PG +G KG  G P     G PG+ G  G+ G+ G PGP G  G      GP G  G  G 
Sbjct: 397  PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 897  TGKPGPKGTSGGDGPP--------------------------------------GPPGER 918
             G PG  G  G  G P                                      G PG  
Sbjct: 457  LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 919  GPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
            G  G  G  GFPG +G PG          P G+ G+PG PG RG+ G +G  G PG  GV
Sbjct: 517  GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 969  VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKE-----GAKGDPGPQGISGKDGPA 1023
             G  GP GE    GE+G  GPPG PG  G PG AG       G +G+PG QG  G  G  
Sbjct: 577  KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636

Query: 1024 GLRGFPGERG-------LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G RG       +PG  G PG  G  GPQGPPG  GS G+ G  G  GP G PG 
Sbjct: 637  GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI 696

Query: 1077 PGP--QGPPGPAGEKGAPGEKGP---QGPAGRDGVQGPVGLPG---------PAGPA--G 1120
            PG    GPPGP G++G PG KG     G  G  G+ G  GLPG         P GP   G
Sbjct: 697  PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPG 756

Query: 1121 SPGEDGDKGEIGE------------PGQKGSKGDKGENGPPGPPGLQGPVG--APGIAGG 1166
             PGE G+ GE GE            PG +G  G +G+ G PGPPG QGP G    G  G 
Sbjct: 757  FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGA 816

Query: 1167 DGEPGPRGQQGMFGQKGDEGARGFPGPPGP-----IGLQGLPGPPGEKGENGDVGPMGPP 1221
             G PG  G +G  G++G  G +G PG PG       G  G PG PG +GE G +G  G P
Sbjct: 817  QGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP---GEAGVGGPKGER 1278
            G PG  GP G +G  G  G PG++G  G  G  G PG+ G+PG P   G+ G  G KGE+
Sbjct: 877  GNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936

Query: 1279 GEKGEAGPP------GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG 1332
            G+KG  GP       G  G PG KG  G+ G KGN G  G PG  G  G PGPAG  G  
Sbjct: 937  GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996

Query: 1333 GDKGEDGDPGQP---GPPGPSGEAGPPGPPGKR--------------------------- 1362
            GD G  G+PG+P   G PG  G  G PG  GKR                           
Sbjct: 997  GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056

Query: 1363 --------GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG 1414
                    GPPG  G  G  G+ G KGE G  GPPG  GP GP+G  G PG  GL G PG
Sbjct: 1057 GYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG 1116

Query: 1415 PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP----------- 1463
            P G+ G  G  G  GPPG  GPPGLPG  G PG  G +G  G  G+ GP           
Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLR 1176

Query: 1464 --------PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP---PGPPGLPGPQGPK 1512
                    PG QG KGDRG PG  G PG KG  G  GP GP G    PGPPGLPG   P 
Sbjct: 1177 APPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP- 1235

Query: 1513 GNKGSTGPAGQKGDSGLPGPPGSPG 1537
            G  G+ GP G +G  G PGPPG PG
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPG 1260



 Score =  796 bits (2055), Expect = 0.0
 Identities = 489/1139 (42%), Positives = 571/1139 (50%), Gaps = 113/1139 (9%)

Query: 365  IDGRDSDLLVDGDLGEYDFYE-YKEYEDKPTSPPNEEFG----------PGVPAETDITE 413
            I G+  D+   G  G  ++Y+ Y+E  D+ T  P    G          PGVP     + 
Sbjct: 328  IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387

Query: 414  TSINGHGAY-GEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD----- 467
              + G   + G KG KGE     PG    G PG  G AG  G PG  GP GPPGD     
Sbjct: 388  PGLRGAPGWPGLKGSKGERG--RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 468  --PGDRGPPG---RPGLPGADGLPGPPGTML-MLPFRYGGDGSKGPTISAQEAQAQAILQ 521
              PGD G PG    PG+PG DG  G PG +    P+  G  G  G  +           +
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG--LPGLHGVKGIPGR 503

Query: 522  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPG----PQGPRGVQGPPGPTGKPG 577
            Q    L+G PG  G TG PG  G PG+ G  G  G+ G    P+G  GV G PG  G+PG
Sbjct: 504  QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563

Query: 578  KRGRPGADGGRGMPGEPGAKGD------RGFDGLPGLPGDKGHRGERGPQGPPG--PPGD 629
            ++G  G  G  G+ G PG KG+      +G  G PG PG  G  G  GP GPPG  P G+
Sbjct: 564  RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623

Query: 630  DGMRGEDGEIGPRGLPGEAGPRGLLGPR----GTPGAPGQPGMAGVDGPPGPKGNMGPQG 685
             G++G  G  G  G PGEAGPRG L       G PG PG PG  G  GPPG  G++G  G
Sbjct: 624  PGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCG 683

Query: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745
            +PG PG  G PG  G+  P GP GP G++G  G  G  G PG  G PG PGK G  G KG
Sbjct: 684  DPGLPGPDGEPGIPGIGFP-GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKG 742

Query: 746  --ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQ 803
              A+  PG  G  G+PG RG  G  G  GL G  G       PG  G+ GL G RG+ GQ
Sbjct: 743  EPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG------LPGTPGNEGLDGPRGDPGQ 796

Query: 804  IGPRGEDGP-----EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG--RQGPKGSTG 856
             GP GE GP     EGP+G  G  G  G  GQ G +GK G  G PG PG  R G  G TG
Sbjct: 797  PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETG 856

Query: 857  FPGFPGANGEKGARGVAGKPG------PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDG 910
             PG PG  GE G  G  G PG      P G+ G  G  G  GA GP G PG  GT G  G
Sbjct: 857  SPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916

Query: 911  PPGPPGERGPQGPQGPVGFPGPKGPPGPP---------GKDGLPGHPGQRGETGFQGKTG 961
             PG PG +G +G  G  G  G KG PGP          G+ GL G  G  GE G +G  G
Sbjct: 917  SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPG 976

Query: 962  PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021
             PG  G+ G  GP G  GP G+ G  G PG PG +G+PG+ G  G  G  G +G  G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG--- 1078
             AG  G PG  GL G +G PG   G  P GPPGP G PG  G  G  G +G PG PG   
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRP-GPPGPTGDPGLPGDMGKKGEMGQPGPPGHLG 1095

Query: 1079 ---PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG------SPGEDGDKG 1129
               P+G PG  G  G PG+ GP G  G  G++G +G PG  GP G      SPG  G +G
Sbjct: 1096 PAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRG 1155

Query: 1130 EIGEPGQKGSKGDKGENG----PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDE 1185
            + G  G  G  G+KGE G    PPGP G  G  GA G  G  G PG  G++G  G  G  
Sbjct: 1156 DQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPR 1215

Query: 1186 GARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPGP--------RGPQGPNGA 1235
            G  G  G PGP GL G  +PG  G +G  G  G  G PGPPGP        +G +G  G 
Sbjct: 1216 GPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGH 1275

Query: 1236 DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGA 1295
             GP+GPPG+ G +G  G  G PG  G PGP G+ G  G  G +GEKG  G  G+ GPPG 
Sbjct: 1276 PGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGP 1335

Query: 1296 KGPPGDDGPKGNPGP---VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
             GP G  G +G+PG    +  PG PGPPG P         G+ G  G+PG PGPPG  G 
Sbjct: 1336 IGPKGPPGVRGDPGTLKIISLPGSPGPPGTP---------GEPGMQGEPGPPGPPGNLGP 1386

Query: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1411
             GP G PGK G PG  G  G +G KG+KGE G  G  G  G  G +G +G P     RG
Sbjct: 1387 CGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  759 bits (1960), Expect = 0.0
 Identities = 468/1085 (43%), Positives = 540/1085 (49%), Gaps = 142/1085 (13%)

Query: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654
            GAKG++G  G PG PG  G +G  GP+G PGP G  G  G  G  G +G+ G +G  G  
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 655  GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG-- 712
            G  G PG PG  G  G+ G PG  G+ G QG PG PG  G PG  G  G +G  G P   
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 713  ---EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---PRGVKG 766
               E   +G PGL G PG  G PG PG  G       +GPPGP G  G+PG   PRG KG
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGP------VGPPGPPGFFGFPGAMGPRGPKG 216

Query: 767  ADGVR--GLKGSKGEKGEDGFPGFKGDM-----------GLKGDRGEVGQIGPRGEDGPE 813
              G R  G KG +G KG  G PG  G +            LKG++G+ G +G   E GP 
Sbjct: 217  HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMG---EPGPP 273

Query: 814  GPKGRAGPT--GDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARG 871
            GP G  G +   + G  G  G +GK G  G+PG+PG +G KG+ GFPG  G +G KG +G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP----- 926
              G PG RG          +G  G  G PGP+G  G  GP GPPG  G  G   P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 927  ---VGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGKTGPPGPGGVV----GPQGPTGE 977
                G  G KG  G PGKD  G PG PG  G  G  G  GPPGP G +    GP G  G 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 978  TGPIGERGHPGPPGP--------------PGEQGLPGAAGKEGAKGDPGPQG---ISGKD 1020
             G +G  G PG  GP              PG  GLPG  G  G KG PG QG   + G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEG----PQGPPGPVGSPGERGSAGTAGPIGLPGR 1076
            G  G  G PG  G PGAQG PGLKG +G    P+G  G  G PG RG  G  G  G+PG 
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG-----SPGEDGDKGEI 1131
            PG +G PGP GE    GEKG QGP G  G  G  G  GPAGP G      PG  G +G  
Sbjct: 574  PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 1132 GEPGQKGSKGDKGE----------NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ 1181
            G PG  G  G +GE           GPPGPPG  GP G PGI G  G+ G  G  G  G+
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 1182 KGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241
             G  G  GFPGPPGP G QG PG  G  G  G +G  G PG PG  G +G      P GP
Sbjct: 694  PGIPGI-GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752

Query: 1242 -----PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG---EAGPPGAA--G 1291
                 PG  G+ G  GE G PG  G PG PG  G+ GP+G+ G+ G   E GPPG    G
Sbjct: 753  GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG 812

Query: 1292 PPGAKGPPG------------DDGPKGNPG-----PVGFPGDPGPPGEPGPAGQDGVGGD 1334
            P GA+G PG              GPKG+PG       GFPG+ G PG PG  G+ G  G 
Sbjct: 813  PRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQ 872

Query: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
            +G  G+PG  GPPG  G  G  G PG  GPPG  G  G  G++G+ G  G +G  G  G 
Sbjct: 873  RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK----------- 1443
             G QG  G PGP  +  + G  GE GL G AG  G  G  G PG+PGLK           
Sbjct: 933  KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992

Query: 1444 ----------GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP------GAKGD 1487
                      G+PG  G +G PG +G +G PG +G++G  G PG  G P      G +GD
Sbjct: 993  PGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGD 1052

Query: 1488 GGIPGPA-----GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542
             G PG +     GP GP G PGLPG  G KG  G  GP G  G +G  G PGSPG PG  
Sbjct: 1053 KGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLP 1112

Query: 1543 IQPLP 1547
             +P P
Sbjct: 1113 GKPGP 1117



 Score =  585 bits (1507), Expect = e-166
 Identities = 380/913 (41%), Positives = 434/913 (47%), Gaps = 178/913 (19%)

Query: 824  DPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST------------GFPGFPGANGEKGARG 871
            D G     G KG+ G  G PG PG  G KG T            GFPG PG  G KG RG
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 872  VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG------------------------ 907
            ++G PG  G  G  G  G+ G  G  G PG  G+ G                        
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 908  --------------GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP-------- 945
                            G PG PG  GPQG  GP GFPGP GPPGPPG  G P        
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 946  -GHPGQR-----GETGFQGKTGPPGPGGVV-----GPQGPTGETGPIGERGHPGPPGPPG 994
             GH G+R     GE G +G TGPPGP G V     GP   T   G  G++G  G PGPPG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 995  EQGLPGAA--GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP 1052
              GLPG +   ++GA GDPG QG  GKD   G+ GFPG  G+ G +G PGL G +G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKD---GVPGFPGSEGVKGNRGFPGLMGEDGIKGQ 331

Query: 1053 PGPVGSPG------------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP-------- 1092
             G +G PG            E+G  GT GP G  G  GPQGP GP G  G+P        
Sbjct: 332  KGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLR 391

Query: 1093 ---------GEKGPQGPAGRD--------GVQGPVGLPGPAGPAGSPGE----DGDKGEI 1131
                     G KG +G  G+D        G  G  GLPG  GP G PG+     G  G+ 
Sbjct: 392  GAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451

Query: 1132 GEPGQKGSKGDKGENGPPGPPGL--------QGPVGAPGIAGGDGEPGPRGQQGMFGQKG 1183
            G PG  GS G  G +GP G PGL         GP G PG+ G  G  G  G+QG  G KG
Sbjct: 452  GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511

Query: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQ 1239
              G+ G  G PG  G  G  G PG KGE G+     G +G PG PG RG  G  G DG  
Sbjct: 512  SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIP 571

Query: 1240 GPPGSVGSVGGVGE---------KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290
            G PG  G  G  GE         +G PG+ G+PG PG AG  GP G  G +GE G  G  
Sbjct: 572  GTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQ 630

Query: 1291 GPPGAKGPPGDDGPKGN-------PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
            G PGA GPPG+ GP+G        PGP   PG PGPPG PGP G  G+ G  G+ GDPG 
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPVPGP---PGPPGPPGHPGPQGPPGIPGSLGKCGDPGL 687

Query: 1344 PGPPGPSG--EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG----- 1396
            PGP G  G    G PGPPG +G  G  G +G  G  G  GE G  G PG  G  G     
Sbjct: 688  PGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVA 747

Query: 1397 -PQGPA--------GKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP- 1446
             P GP         G  G  G  G+PG  G  G PG  G DGP G  G PG PG +G P 
Sbjct: 748  MPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPG 807

Query: 1447 ----GSKGEKGHPGLIGLIGPPGEQGE---KGDRGLPG--TQGSPGAKGDGGIP---GPA 1494
                G +G +G PGL GL G  G +G+   KGD G+PG    G PG  G  GIP   G  
Sbjct: 808  RCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867

Query: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1554
            GPLG  G PG PG  GP G  G  G  G  G  G PGPPG+PG PG+  +  P +   K 
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ--RGSPGIPGVKG 925

Query: 1555 RRHTEGMQADADD 1567
            +R T G + +  D
Sbjct: 926  QRGTPGAKGEQGD 938



 Score =  432 bits (1110), Expect = e-120
 Identities = 274/640 (42%), Positives = 312/640 (48%), Gaps = 100/640 (15%)

Query: 1001 AAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
            AA K     D G     G  G  G +GFPG  G PG +G  G +G  GPQGP G  G PG
Sbjct: 26   AASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPG 85

Query: 1061 ERGSAGT---------AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVG 1111
              GS G          +G  GLPG PG  GP G  G  G  G KG QG  G  G  G  G
Sbjct: 86   LTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145

Query: 1112 LPGPAGPAGSPG-----EDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG 1166
            +PG AG  G  G     ED +    G+PG  G+ G +G  GPPG PG  GP G PG  G 
Sbjct: 146  IPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGF 205

Query: 1167 DGEPGPRGQQG-----MFGQKGDEGARGFPGPPGPIG--LQGLPGPPGE---KGENGDVG 1216
             G  GPRG +G     + G KG+ G +G  GPPGP G  +  L GP      KGE GD G
Sbjct: 206  PGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKG 265

Query: 1217 PMGPPGPPGPRG--------PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
             MG PGPPGP G         +G  G  G QG PG  G  G  G +G  G  G PG  GE
Sbjct: 266  AMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 1269 AGVGGPKGERG---------------EKGEAGPPGAAGPPGAKGPPGDDGPKGNP----- 1308
             G+ G KG+ G               EKG+ G PG  GP GA+GP G  GP G P     
Sbjct: 326  DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 1309 ------GPVGFPGDPGPPGEPGPAGQDGVG-----GDKGEDGDPGQPGPPGPSGE----A 1353
                  G  G+PG  G  GE G  G+D +G     G  G  G PG PGPPGP G+     
Sbjct: 386  SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 1354 GPPGP---PGKRGPPGAAGAEGRQGE-----------------KGAKGEAGAEGPPGKTG 1393
            GPPG    PG  G PG  G +G +GE                  G  G  G +G PG+ G
Sbjct: 446  GPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQG 505

Query: 1394 PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDG----PPGPMGPPGLPGLKGDPGSK 1449
              G +G  G PG  GL G PG  G QG PG  G+ G    P G +G PG PGL+G PG K
Sbjct: 506  AAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRK 565

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPP--GPPGLPG 1507
            G  G PG  G+ G PG +GE    G  G QG PG  G  G PGPAGP GPP  GP G PG
Sbjct: 566  GLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625

Query: 1508 PQGPKGNKGSTGPAGQKGDSG-------LPGPPGSPGPPG 1540
             QG +G  G+ GP G+ G  G       +PGPPG PGPPG
Sbjct: 626  LQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score =  162 bits (410), Expect = 3e-39
 Identities = 106/266 (39%), Positives = 124/266 (46%), Gaps = 29/266 (10%)

Query: 420  GAYGEKGQKGEPAVVE-PG----MLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPP 474
            GA G KG +G P     PG    M   GP GP G  G  GPPGL G    PG  G+RGPP
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPP 1244

Query: 475  GRPGLPGADGLPGPPGTMLML----PFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRG 529
            G  G PGA G PGPPG+ ++         G  G KGP  +A +      L       L G
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPG 1304

Query: 530  PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQG------------------PPG 571
            P G  G  G PG  G  G+ G  G  G PGP GP+G  G                  PPG
Sbjct: 1305 PRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG 1364

Query: 572  PTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
              G+PG +G PG  G  G  G  G +G  G DG PG PG  G +G +G +G PGP G DG
Sbjct: 1365 TPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDG 1424

Query: 632  MRGEDGEIGPRGLPGEAGPRGLLGPR 657
            + G  G+ G  G P     RG +  R
Sbjct: 1425 LPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score =  155 bits (391), Expect = 4e-37
 Identities = 106/274 (38%), Positives = 122/274 (44%), Gaps = 60/274 (21%)

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVG---PQGPAGKPGPEGLRGIPGPVGEQGLPGAA 1425
            GA+G +GEKG  G  G+ G  G TGP G   PQGP G PG  GL G  G  G  GLPG +
Sbjct: 43   GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 1426 GQDG---PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE------------- 1469
            G  G    PG  GP GL G+ G  GSKGE+G PGL G +G PG  G              
Sbjct: 103  GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 1470 -------KGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA- 1521
                   KGD GLPG  G  G  G  G PGP GP GPPG  G PG  GP+G KG  G   
Sbjct: 163  EDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERV 222

Query: 1522 -------GQKGDSGLPGPPGS--------------------------PGPPGEVIQPLPI 1548
                   G KG +G PGPPG+                          PGPPG    P   
Sbjct: 223  IGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGES 282

Query: 1549 LSSKKTRRHTEGMQADADDNILDYSDGMEEIFGS 1582
              S+K      G+Q     + +    G E + G+
Sbjct: 283  YGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGN 316



 Score =  130 bits (327), Expect = 1e-29
 Identities = 90/239 (37%), Positives = 102/239 (42%), Gaps = 21/239 (8%)

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455
            PP     PG P       + + G    G+KG  G P          GP GP G AG MGP
Sbjct: 1243 PPGSRGSPGAPGPPGPPGSHVIG--IKGDKGSMGHP----------GPKGPPGTAGDMGP 1290

Query: 456  PGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
            PG  G  G PG PG RG PG  G PG  G  G PG +  +    G  G KGP     +  
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIG-PPGPIGPKGPPGVRGDPG 1349

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG---P 572
               I     I+L G PGP G  G PG  G PG  G  G  G  GP+G  G  G PG   P
Sbjct: 1350 TLKI-----ISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404

Query: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 631
             G+ G +G  G  G  G  G PG KG RG  G P     +G    R  Q    P   +G
Sbjct: 1405 AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG 1463


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  871 bits (2250), Expect = 0.0
 Identities = 533/1213 (43%), Positives = 606/1213 (49%), Gaps = 174/1213 (14%)

Query: 454  GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 512
            GP  +   T PP  P    PP RP  PG++ +          P    G+ G  GP     
Sbjct: 441  GPCQVTVVTEPPPPP----PPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM---- 492

Query: 513  EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGP 572
                            G PGP G  G  GPVG PG  G KG+ G     GP G QG  G 
Sbjct: 493  ----------------GLPGPKGDIGAIGPVGAPGPKGEKGDVGI----GPFG-QGEKGE 531

Query: 573  TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 632
             G  G  G PG DG +GM GEPG  G+      PGLPG+ G RG +GP G PGPPG  G 
Sbjct: 532  KGSLGLPGPPGRDGSKGMRGEPGELGE------PGLPGEVGMRGPQGPPGLPGPPGRVGA 585

Query: 633  RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGP 689
             G  GE G +G  GE G RGL G  G PG  GQ   PG +GV GP G KG++GP G PG 
Sbjct: 586  PGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGV 645

Query: 690  PG----------QQGNPGP---QGLPGP---QGPIGPPGEKGPQGKPGLAGLPGADGPPG 733
            PG          +QG PGP   QG PGP   +GPIGP G  GP G  GL G  G  GPPG
Sbjct: 646  PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705

Query: 734  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793
             PG  G  G      PPGP G  G PGP G  G  G  G  G  G  G  G PG  G  G
Sbjct: 706  IPGLLGLQG------PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNG 759

Query: 794  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 853
              G  G  G+ G RGEDG  G  G  G  G+ G +G+ GEKG+ G+PG PG+PG +G KG
Sbjct: 760  PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819

Query: 854  STGFPG---FPGANGEKGARGVAGKPGPRGQRGPTG-----PRGSRGARGPTGKPGPKGT 905
              G  G    PG  G++G +G AG  GP G  G T      PR   G +GP G+ G  G 
Sbjct: 820  DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR-MPGEQGPKGEKGDPGL 878

Query: 906  SGGDGPPGPPGERGPQGPQGPVGFPGPKGP---PGPPGKDGLPGHPGQRGETGFQGKTGP 962
             G  G  G PGE GPQGP GP G  G +G    PG  G  G PGH G  G +G  G  G 
Sbjct: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938

Query: 963  PGPGGVVGPQGPTGETGPIGERGHPGPPGP---PGEQGLPGAAGKEGAKGDPGPQGISGK 1019
            PG  G  G  G  GE G  GE G PGP GP   PG  GLPG  GK G  G+PG +G  G 
Sbjct: 939  PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGL 997

Query: 1020 DGPAGLRG-----------------FPGERGLPGAQGAPGLKG--GEGPQGPPGPVGSPG 1060
             GP G +                    G+RG PG  G+PG +G  G G  GPPGP G PG
Sbjct: 998  PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057

Query: 1061 ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL-------- 1112
            ++GS G+ G   LPG PGPQGP G  G  G PGE+GP G  G   +  P  +        
Sbjct: 1058 DKGSPGSRG---LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114

Query: 1113 ----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG---PPGLQGPVGAPGIAG 1165
                PGP G  G PG  GDKG  G+PG++G++G KGE GPPG   PPG+ GP G+ G  G
Sbjct: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174

Query: 1166 GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225
             DGE G +G QG  G  G  G  G PGPPG  G+ G  GPPG +G  G  GP GP GP G
Sbjct: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234

Query: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG------EAGVGGPKGERG 1279
              G  G  G +G  G PG  G  G  GE G PG  G  GPPG      ++G  GP+GE G
Sbjct: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294

Query: 1280 EKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG 1339
              G  G  G  G  G  GP G  GP+G  GP G  G PG PGEPGP+G  G  G KGE+G
Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354

Query: 1340 DPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG 1399
             PG PG  GP G   PPG PG++G PG  G  G+ GE G KGE G  G  G  GP G +G
Sbjct: 1355 SPGLPGFLGPRG---PPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411

Query: 1400 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-------------- 1445
              G PG  G +G  G +G QGLPG  G  GPPGP G PG PGL+G+              
Sbjct: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471

Query: 1446 ---------------------------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
                                       PG  G  G  GL G  GP GE G  G  GL G 
Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 1531

Query: 1479 ------QGSPGAKGDGGIPGPA--GPLGPPGPPGLPGPQG--PKGNKGSTGPAGQKGDSG 1528
                  +G  GAKGD G PG    G +GPPG PG PG  G    G  G  GP G+ G +G
Sbjct: 1532 SGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1591

Query: 1529 LPGPPGSPGPPGE 1541
             PG PG PGPPG+
Sbjct: 1592 HPGLPGPPGPPGQ 1604



 Score =  854 bits (2206), Expect = 0.0
 Identities = 528/1205 (43%), Positives = 601/1205 (49%), Gaps = 164/1205 (13%)

Query: 392  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 451
            +P  PP  +  P   +E      +IN     GEKG+ G          V GP G  GP G
Sbjct: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMG----------VAGPMGLPGPKG 499

Query: 452  IMGPPGLQGPTGPPGDPGDRG----PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 507
             +G  G  G  GP G+ GD G      G  G  G+ GLPGPPG           DGSKG 
Sbjct: 500  DIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGR----------DGSKGM 549

Query: 508  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 567
                 E     +     + +RGP GP GL G PG VG PG  G +GE G  G +G RG+ 
Sbjct: 550  RGEPGELGEPGL--PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD 607

Query: 568  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP-------GLPGDKGHRGERGP 620
            G PG  G  G++GRPG  G  G  GE G  G  G  G+P       GL G++G  G RG 
Sbjct: 608  GFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGH 667

Query: 621  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTP---GAPGQPGMAGVDGPPGP 677
            QG PGPPG  G  G +G  GP GL G  G +G +GP G P   G  G PG  GV GPPGP
Sbjct: 668  QGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 678  KGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGK 737
             G+ G  GE G PG+ G PGP G PG  GP GPPG  G +G+PG     G DG PG PG 
Sbjct: 728  GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER---GEDGLPGKPGL 784

Query: 738  EGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGD 797
             G+ GE+G  G PG +G  G P   G  G  GVRG KG +GEKGE G P      GLKGD
Sbjct: 785  RGEIGEQGLAGRPGEKGEAGLP---GAPGFPGVRGEKGDQGEKGELGLP------GLKGD 835

Query: 798  RGEVGQIGPRGEDGPEGPKGRAGP----TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 853
            RGE G+ GP G  G  G      P     G+ GP G+ G+ G  G PGL G PG  GP+G
Sbjct: 836  RGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQG 895

Query: 854  STGFPGFPGANGEKGARGVAGKPGPRGQ---RGPTGPRGSRGA---RGPTGKPGPKGTSG 907
             TG PG  G  G  GA G AG PG  G     GP+GP GS GA   RG  GK G +G  G
Sbjct: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955

Query: 908  GDGPPGPPGERGPQGPQGPVGFPGP--KGPPGPPGKDGLPGHPGQRGETGFQGKT----- 960
              G  G PG  GP+G  G  G PGP  KG  G PG  G PG PG  G     GK      
Sbjct: 956  AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSEN 1015

Query: 961  ---------GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011
                     G  G  G+ G  G  G+ G IG  G PGP GPPG++G PG+ G  G  G  
Sbjct: 1016 CALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074

Query: 1012 GPQGISGKDGPAGLRGFPGERGL---------------------PGAQGAPGLKGGEGPQ 1050
            GP G  G  G  G RG PG+ GL                     PG  G PGL G +G +
Sbjct: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1110
            G PG  G  G  G  G AGP GLPG PG  GP G  GE+GA GE G +G  G  GV G +
Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194

Query: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL---------------Q 1155
            G PG  GP   PG DG  G  G PG +GS G +G  GP GP GL                
Sbjct: 1195 GPPGNPGP---PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251

Query: 1156 GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV 1215
            GP G PG AG  G PGP G +G  G KG  G  G PGP G  G  GLPG  G  G++GD 
Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311

Query: 1216 GPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1275
            GP GP GP GPRGP G NG+ G  G PG  G+    G+KG  GE G+PG PG  G  GP 
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQKGSKGENGSPGLPGFLGPRGPP 1368

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDK 1335
            GE GEK   G PG  G PG  G PG  G +G+P   G  GD GPPG  G  G  G+ G K
Sbjct: 1369 GEPGEK---GVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKGQPGDPGIPGHK 1422

Query: 1336 GEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAE--------------GRQGE----- 1376
            G  G  G  G PG +G  GPPGPPG+ G PG  G                G+Q E     
Sbjct: 1423 GHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAY 1482

Query: 1377 ----------KGAKGEAGAEGPPGK---TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPG 1423
                      K ++G  G  GPPGK    G  GP G  G+PG  GL G  GP+G +G  G
Sbjct: 1483 LLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERG 1542

Query: 1424 AAGQDGPP-----GPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
            A G  G P     G MGPPG+PG  G+PG   +    GL G+ GP GE G  G  GLPG 
Sbjct: 1543 AKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD----GLPGIPGPQGETGPAGHPGLPGP 1598

Query: 1479 QGSPG 1483
             G PG
Sbjct: 1599 PGPPG 1603



 Score =  654 bits (1686), Expect = 0.0
 Identities = 418/1042 (40%), Positives = 484/1042 (46%), Gaps = 216/1042 (20%)

Query: 396  PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIMG 454
            PP     PG+  E     T     G  GE+G  G P   +PG    +G PGP+G AG  G
Sbjct: 579  PPGRVGAPGLQGERGEKGT----RGEKGERGLDGFPG--KPGDTGQQGRPGPSGVAGPQG 632

Query: 455  PPGLQGPTGPPGDPGD-------RGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 507
              G  GP GPPG PG        +G  G PG  G  G PGPPG    +    G +G  GP
Sbjct: 633  EKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI----GPEGRDGP 688

Query: 508  T----ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGA---KGESGDPGP 560
                 +  ++           + L+GPPGP G+ G PGP G PG  G     G+ G PGP
Sbjct: 689  PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGP 748

Query: 561  QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620
             GP G  GP GP G PG +G PG  G  G+PG+PG +G+ G  GL G PG+KG  G  G 
Sbjct: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808

Query: 621  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG-------QPGMAGVDG 673
             G PG  G+ G +GE GE+G  GL G+ G +G  GP G PG PG        P M G  G
Sbjct: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQG 868

Query: 674  PPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP------QGPIGPPGEKGPQGKPGLAGLPG 727
            P G KG+ G  GEPG  G+ G  GPQG  GP      +G  G PG  G  G PG  G PG
Sbjct: 869  PKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG 928

Query: 728  ADGPPGH---------PGKEGQSGEKGALGP---PGPQGPIGYPGPRGV-----KGADGV 770
              GPPG          PGK+G+ GEKGA G    PGP GP G PG  G+     KG DG 
Sbjct: 929  PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE 988

Query: 771  RGLKGSKG--------------------------EKGEDGFPGFKGDMGLKGDRGEVGQI 804
             GL+GS G                           KG+ G PG  G  G +GD G +G  
Sbjct: 989  PGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVA 1047

Query: 805  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST--------- 855
            GP G  GP G KG  G  G PG  G  G  G+ G PG PG  G  G  G +         
Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107

Query: 856  ------------GFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 903
                        G PG PG  G KG +GV GKPG  G  G  G  G  G  GP G  GP+
Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ 1167

Query: 904  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 963
            G+ G  G  G  G++G QG  G  GF GP G PGPPG DG+ G  G  G  G  GK GPP
Sbjct: 1168 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 1227

Query: 964  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023
            GP G  G  G  GE G  G  G PGPPG PG+ G PG  G EGA+G PG +G +G  G  
Sbjct: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP 1287

Query: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGP---------------------PGPVGSPGER 1062
            G RG  G  GLPG +G PG  G  GP GP                     PGP G+PG++
Sbjct: 1288 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK 1347

Query: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE---------------------KGPQGPA 1101
            GS G  G  GLPG  GP+GPPG  GEKG PG+                     KG +GP 
Sbjct: 1348 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPP 1407

Query: 1102 GRDGVQGPVGLPGPAG------PAGSPGEDGDKGEIGEPGQKGSKGDKGEN--------- 1146
            G  G  G  G+PG  G      P G PGE+G  G  G PGQ G  G +GE+         
Sbjct: 1408 GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 1467

Query: 1147 -----------------------------GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1177
                                         G PGPPG  G  G PG AG  GEPG  GQ G
Sbjct: 1468 IQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG 1527

Query: 1178 M------FGQKGDEGARGFPGPPGPIGLQG--------------------LPGPPGEKGE 1211
            +       G KG+ GA+G PG PG +GL+G                    LPG PG +GE
Sbjct: 1528 LEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGE 1586

Query: 1212 NGDVGPMGPPGPPGPRGPQGPN 1233
             G  G  G PGPPGP G   P+
Sbjct: 1587 TGPAGHPGLPGPPGPPGQCDPS 1608



 Score =  652 bits (1683), Expect = 0.0
 Identities = 385/876 (43%), Positives = 438/876 (50%), Gaps = 157/876 (17%)

Query: 815  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874
            P G  G  G  GP G  G KG +G  G  G PG +G KG  G   F    GEKG +G  G
Sbjct: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPF--GQGEKGEKGSLG 536

Query: 875  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 934
             PGP G+ G  G RG  G  G  G PG  G  G  GPPG PG  G  G  G  G  G KG
Sbjct: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596

Query: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP----P 990
              G  G+ GL G PG+ G+TG QG+   PGP GV GPQG  G+ GP G  G PG      
Sbjct: 597  TRGEKGERGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQE 653

Query: 991  GPPGEQGLPGAAGKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047
            G  GEQG PG  G +GA G PG   P G  G+DGP GL+G  G++G  G  G PGL G +
Sbjct: 654  GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQ 713

Query: 1048 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP------------QGPPGPAGEKGAPGEK 1095
            GP GPPG  G PG  GS G  G IG PG+PGP             GPPGP G KG PGE+
Sbjct: 714  GPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGER 773

Query: 1096 GP---------------QGPAGRDGVQGPVGLPGPAGPAGSPGEDGD---KGEIGEPGQK 1137
            G                QG AGR G +G  GLPG  G  G  GE GD   KGE+G PG K
Sbjct: 774  GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833

Query: 1138 GSKGDKGENGPPGPPGL----------------QGPVGA---------PGIAGGDGEPGP 1172
            G +G+KGE GP GPPGL                QGP G          PG+ G  GE GP
Sbjct: 834  GDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893

Query: 1173 RGQQGMFGQKGDEGARGFPG------------------PPGPIGLQGLPGPPGEKGENGD 1214
            +G  G  G KG EGA G PG                  PPG +G  GL G PG+ GE G+
Sbjct: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953

Query: 1215 VGPMGPPGPPGPRGPQGPNGADGPQGPPG-----------------------SVGSVGGV 1251
             G  G  G PGP GP+G  GA G  GPPG                       + G V G 
Sbjct: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGS 1013

Query: 1252 -----------GEKGEPGEAGNPGPPGEAGVG-----GPKGERGEKGEAGPPGAAGPPGA 1295
                       G++G PG  G+PG  G+ G+G     GP G  G+KG  G  G  G PG 
Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP 1073

Query: 1296 KGPPGDDGPKGNPGPVGFPGDPG---------------------PPGEPGPAGQDGVGGD 1334
            +GP G DG  GNPG  G PG PG                     PPG PG  G  G  GD
Sbjct: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133

Query: 1335 KGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGP 1394
            KG  G PG+ G  G  GEAGPPG PG   PPG AG +G QGE+GA GE G +G  G  G 
Sbjct: 1134 KGVPGKPGREGTEGKKGEAGPPGLPG---PPGIAGPQGSQGERGADGEVGQKGDQGHPGV 1190

Query: 1395 VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGH 1454
             G  GP G PGP G  GI G  G  G+ G+ G++GPPGP GP GLPG+ G+ G +G  G 
Sbjct: 1191 PGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGK 1250

Query: 1455 PGLIGLIGPPGEQGEKGDRGLPGTQGS---PGAKGDGGIPGPAGPLGPPGPPGLPGPQGP 1511
            PG      PPGE G+ G+ GLPG +G+   PG KG  G  G  GP G  G  GLPG +G 
Sbjct: 1251 PG------PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 1304

Query: 1512 KGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547
             G  G TGP G +G  G  GPPG  G PG   +P P
Sbjct: 1305 PGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340



 Score =  320 bits (821), Expect = 6e-87
 Identities = 214/553 (38%), Positives = 247/553 (44%), Gaps = 102/553 (18%)

Query: 370  SDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKG 429
            S LL  GD+   +        D P  PP     PG   +  +        G  G +G+KG
Sbjct: 1098 SSLLSPGDI---NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP----GREGTEGKKG 1150

Query: 430  EPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGD------PGDRGPPGRPGLPGAD 483
            E     PG+   GPPG AGP G  G  G  G  G  GD      PG  GPPG PG PGAD
Sbjct: 1151 EAG--PPGL--PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 1206

Query: 484  GLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPV 543
            G+ G  G     P   G  G +GP                     GP GP GL G PG  
Sbjct: 1207 GIAGAAGP----PGIQGSPGKEGPP--------------------GPQGPSGLPGIPGEE 1242

Query: 544  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603
            G  G  G  G  G+PG  G  G+ GP G  G PG +G  G  G  G  GE GA G  G +
Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302

Query: 604  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG---------LL 654
            GLPG  GD G  G +GPQGP GPPG +G  G  GE GP G PG+ G +G          L
Sbjct: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 1362

Query: 655  GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPG------PPGQQGNPGPQGLPGPQ 705
            GPRG PG PG+   PG  GV G PG  G  G +G+PG      PPG +G PG  G+PG +
Sbjct: 1363 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHK 1422

Query: 706  G------PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK--------------- 744
            G      P G PGE GP G P         GPPG PG  G  GE                
Sbjct: 1423 GHTGLMGPQGLPGENGPVGPP---------GPPGQPGFPGLRGESPSMETLRRLIQEELG 1473

Query: 745  -----------GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793
                         + P   +   G PGP G  G DG+ G  G  GE G  G  G +G  G
Sbjct: 1474 KQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533

Query: 794  LKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG 853
              G +GE G  G  G  G  G +G  GP G PG  G+ G   K G+PG+PG  G  GP G
Sbjct: 1534 PIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGPQGETGPAG 1591

Query: 854  STGFPGFPGANGE 866
              G PG PG  G+
Sbjct: 1592 HPGLPGPPGPPGQ 1604



 Score =  229 bits (584), Expect = 2e-59
 Identities = 165/469 (35%), Positives = 194/469 (41%), Gaps = 143/469 (30%)

Query: 403  PGVPAETDIT--ETSINGHGAYGEKGQKGE---PAVVEPGMLVE----GPPGPAGPAGIM 453
            PG+P    I   + S    GA GE GQKG+   P V  PG +      GPPG  G AG  
Sbjct: 1155 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV--PGFMGPPGNPGPPGADGIAGAA 1212

Query: 454  GPPGLQGPTGPPGDPGDRGPPGRPGLPGA------DGLPGPPGTMLML--PFRYGGDGSK 505
            GPPG+QG  G  G PG +GP G PG+PG       DG PGPPG       P   G +G++
Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272

Query: 506  GPTI------------SAQEAQAQAILQQARIALR-------GPPGPMGLTGRPGPVGGP 546
            GP                 E+ A  +  Q  +  +       GP GP G  G PG  G P
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 547  GSSGAKGESGDPGPQGPRGVQGPPG---------PTGKPGKRGRPGADGGRGMPGEPGAK 597
            GS G  G SG PG +G +G  G PG         P G+PG++G PG +G  G PGEPG K
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392

Query: 598  GDRGFDGL---------------PGLPGDKGHRG---------ERGPQGPPGPPGDDG-- 631
            G+RG  G+               PG+PG KGH G         E GP GPPGPPG  G  
Sbjct: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452

Query: 632  ---------------------------------------MRGEDGEIGPRGLPGEAGPRG 652
                                                   M+   G  GP G PG+ G  G
Sbjct: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512

Query: 653  LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPG--------------------- 691
              GP G PG PGQ G+ G  GP GPKG  G +G+PG PG                     
Sbjct: 1513 RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGY 1572

Query: 692  ----------QQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 730
                       QG  GP G PG  GP GPPG+  P      A L    G
Sbjct: 1573 AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 39/174 (22%), Positives = 85/174 (48%), Gaps = 9/174 (5%)

Query: 65  KNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNE 121
           K   G+ ++Y       +   T+ +FP G  P++++ + T + +K  +    ++  + ++
Sbjct: 260 KRENGAQSSYVRMGSFPVVQSTEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQ 318

Query: 122 HGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR---TVNIADGKWHRVAISVEKKTVTM 178
           + I Q+ + +      +  +  G        +FR     ++ D  WH++A+S++ + V++
Sbjct: 319 YSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSL 378

Query: 179 IVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAA 232
            +DC    T P++  ER  +D  G TV G R+ D    + D+Q+ +I  D + A
Sbjct: 379 HIDCALVQTLPIE--ERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHA 430


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  830 bits (2145), Expect = 0.0
 Identities = 535/1293 (41%), Positives = 632/1293 (48%), Gaps = 175/1293 (13%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G  G+KG KG+P V+ PG       G  G  G+ G  G+ GP G PG PG  GP G PGL
Sbjct: 149  GLPGQKGSKGDP-VLAPGSF----KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGL 203

Query: 480  PGADGLPGPPGTMLMLPFRYGGD----------GSKGPTISAQEAQAQAILQQARIALRG 529
             G  G PGP G    +   + G+          G  GP  S  E +      + +   +G
Sbjct: 204  QGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKGSKG 262

Query: 530  PPGPMGLTGRPGPVGGPG--SSGAKGESGD------PGPQGP---RGVQGPPGPTGKPGK 578
             PGP G  G  GP G PG  ++G KGE G+      PGP+GP    GVQGPPG  GK G 
Sbjct: 263  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 322

Query: 579  RGRPGADGGRGMPGEPG-----------------AKGDRGFDGLPGLPGDKGHRGERGPQ 621
             G PG +G +G+ G+ G                   G+ G  G+PGLPG KG  G +G +
Sbjct: 323  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 382

Query: 622  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 681
            GP G PG   + G  G +GP+G PG  G +G  G R T GA G PG  G+ GPPGP G  
Sbjct: 383  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPP 441

Query: 682  GPQ-----------GEPGPPGQQGNPGPQGLPGPQGP------------IGPPGEKGPQG 718
             P+           G PG  G+QG  G  GL G +G              GPPGE GP G
Sbjct: 442  SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 501

Query: 719  KPGLAGLPGADGPPGHPGKEGQSGEKGA------LGPPGPQGPIGYP------GPRGVKG 766
              GL GLPG  G  G  G  G  G  GA      LGP GP+G  G P      G  G +G
Sbjct: 502  PWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRG 561

Query: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826
              G +G +G  GE G+DG PG  G  GL GD G+ G  G +G  G  G KG  GP G PG
Sbjct: 562  DSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG 620

Query: 827  --------PSGQAGEKGKLGVPG---LPG---------YPGRQGPKGSTGFPGFPGANGE 866
                    P G  G+KGK G+PG   LPG          PG  GP G  G PGFPG  G 
Sbjct: 621  NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680

Query: 867  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 926
            +G  G  G+PG  G +G  G  G        G PGP+G  G  G PG PG+ G  G  G 
Sbjct: 681  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740

Query: 927  VGFPGPKGP-----------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975
             G PG KG            PG  G  GL GH G  G++G  G  G  G  G++GP+G  
Sbjct: 741  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800

Query: 976  GETGPIGERGHPGPPGPPG------EQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---R 1026
            G  G  G+ G PG PG  G      + GLPGA G  G  G PG +G  GK GP G    +
Sbjct: 801  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 860

Query: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1086
            G PG +GLPG  G  GLKG  G  G  G     G +G  G+ G +G PG PG  G PG  
Sbjct: 861  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 920

Query: 1087 GEKGAPGEKGPQGPAGRDGVQG---------PVGLPGPAGPAGS---PGEDGDKGEIGEP 1134
            G KG PG  G  GP+GR G  G         PVG+P P  P  +    G+ G +G  G  
Sbjct: 921  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 980

Query: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-DGEPGP---RGQQGMFGQKGDEGARGF 1190
            G  G +GDKGE G PGPPGL G  G PGI  G  G+PGP    G +G+ G KG  G  GF
Sbjct: 981  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040

Query: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPG 1243
            PG PG  G QG+ G PG  G +G  G  G         G PGP+G  G +G  G +G  G
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100

Query: 1244 SVGSVGGVGEKGEPG------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---PG 1294
             +G++G  G KGE G      + G PG PG  GV G +GE G  G +G  GA GP   PG
Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160

Query: 1295 AKGP------PGDDGPKGNPGPVGFPGDPGPP--GEPGPAGQDGVGGDKGEDG-DPGQPG 1345
              GP      PG  G  G PG  G  G PGP   G PGPAG  G  G+KG  G   G PG
Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1220

Query: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405
             PG  G+ G  G PG +GP G  GA G        G+ G  G PG  G  G  GPAG PG
Sbjct: 1221 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPG 1280

Query: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---IG 1462
            P G     G  G+ G PG  G  GP G  G PG  GL G+ G KG +G PG +G    +G
Sbjct: 1281 PPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1340

Query: 1463 PPGEQGEKGDRGLPGTQGSPGAKGDGG-------IPGPAGPLGPPGPPGLPGPQGPKGNK 1515
            PPG+ G  G +G  G +GS G +GD G       +  P GPLG PG  G+PG  G  G +
Sbjct: 1341 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ 1400

Query: 1516 GSTGPAGQKGDSGLPG---PPGSPGPPGEVIQP 1545
            G  G  G KG  G+PG   P G PGPPG +  P
Sbjct: 1401 GPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDP 1433



 Score =  819 bits (2116), Expect = 0.0
 Identities = 548/1326 (41%), Positives = 635/1326 (47%), Gaps = 209/1326 (15%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G+ G  G KGE     PG+L  GP GP G  G MG PG  G  G PG PG  GP G PGL
Sbjct: 68   GSTGLSGLKGERGF--PGLL--GPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGL 123

Query: 480  ------PGADGLPGPPG--TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 531
                   GA G PGP G   +L  P   G  GSKG  + A  +            ++G P
Sbjct: 124  DGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK---------GMKGDP 174

Query: 532  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK--RGRPGADGGRG 589
            G  GL G  GP G PG  GA G +G PG QGP G  GP GP G  G   +G  G  G  G
Sbjct: 175  GLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVG 234

Query: 590  MP---GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP---GPPGDDGM--RGEDGEIGP 641
            +P   G P + G+  F G P   G KG +GE GP+G P   GPPG  G+   GE GE G 
Sbjct: 235  LPGPAGPPPSTGELEFMGFP--KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGE 292

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE------PGP------ 689
            +G+PG  GPRG +G  G  G PGQ G  G  G PG  G  G +G+      PGP      
Sbjct: 293  KGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDI 352

Query: 690  -----PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG---LAGLPGADGPPGHPGKEGQS 741
                  G  G+PG  GLPG +G  G  G +GP G PG   L+G+PGA GP G PG +G  
Sbjct: 353  DGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQ 412

Query: 742  GEKGAL--------------GPPGPQGP--------------IGYPGPRGVKGADGVRGL 773
            G  G                GPPGP GP               G+PG RG +G  G  GL
Sbjct: 413  GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGL 472

Query: 774  KGSKGEK---------------GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 818
            KG KG+                GE G PG  G +GL G +G  G  G  G  GP G  G 
Sbjct: 473  KGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL 532

Query: 819  AGPTGDPGPSGQAGE---------------KGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
             GP G  GP G+ GE                G  G  G+ G PG+ G  G  G PG PG 
Sbjct: 533  VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD 592

Query: 864  NGE--KGARGVAGKPGPRGQRGPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG 919
             G+   G +G+ G PG +G  GP G    G  G  GP G PG KG  G  G  G PG +G
Sbjct: 593  GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG 652

Query: 920  ------PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 973
                    G  GP GFPG  G PGP G  GLPG PGQ G +G +G+  P  PG V  P+ 
Sbjct: 653  ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE--PGSPGLVHLPEL 710

Query: 974  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----ISGKDGPAGLRGF 1028
            P G  GP GE+G PG PG PG+ GLPG  G  G  G  G  G      +G  G  GL+G 
Sbjct: 711  P-GFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGL 769

Query: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
             G +G  G  G PGLK   G  G PG +G  GERGS GT G +G PG PG  GP G  G+
Sbjct: 770  TGHKGFLGDSGLPGLK---GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 826

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148
             G PG  G  G +G  G +G  G  GP G     G  G KG  G PG  G KG  G  G 
Sbjct: 827  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 886

Query: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208
             G P L GP G  G  G  G PG  G  G+    G  G +G PG  G +G  G  G PGE
Sbjct: 887  AGLPALSGPKGEKGSVGFVGFPGIPGLPGI---PGTRGLKGIPGSTGKMGPSGRAGTPGE 943

Query: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
            KG+ G+ GP+   G P PR P       G +G  GS GS G  G +G+ GEAG PGPPG 
Sbjct: 944  KGDRGNPGPV---GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGL 1000

Query: 1269 AGVGGPKG-ERGEKGEAGPP---GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324
             G  G  G  +G  G+ GPP   G  G PG KG  G  G  G PG  G  G  G PG PG
Sbjct: 1001 PGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1060

Query: 1325 PAGQDGVGGDKGE----DGDPGQPGPPGPSGEAGPPGP---------PGKRGPPGAAGAE 1371
             +G  G+ GD G+     G PG  G PG SG  G  G          PG +G  G  G  
Sbjct: 1061 ASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVS 1120

Query: 1372 GRQGEKGA---------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1422
            G  G  GA         +GE G  G  G  G +GP G  G  GP+G  G PG  G  GLP
Sbjct: 1121 GDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLP 1180

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL-IGLIGPPGEQGEKGDRGLPGTQ-- 1479
            G  G  G PGP    G+PG  G PG KGEKG+PG+ IG  G PG +G+KGDRG PG Q  
Sbjct: 1181 GTKGTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGP 1239

Query: 1480 ----------------------GSPGAKGDGGIPGPAGPLGPPGP------------PGL 1505
                                  G PG  G+ G PGPAGP GPPGP            PG+
Sbjct: 1240 AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGI 1299

Query: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP---GPPGEVIQP----LPILSSKKTRRHT 1558
            PGP+GPKG++G  G +G  G+ GL G  G P   G PG+V  P     P +  K   R +
Sbjct: 1300 PGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGS 1359

Query: 1559 EGMQAD 1564
             G+Q D
Sbjct: 1360 SGLQGD 1365



 Score =  761 bits (1966), Expect = 0.0
 Identities = 484/1121 (43%), Positives = 553/1121 (49%), Gaps = 141/1121 (12%)

Query: 528  RGPPGPMGLTGRPGPVGGPGS---SGAKGESGDPG---PQGPRGVQGP------------ 569
            RG PGP+G+ G  GP G  GS   SG KGE G PG   P GP+G +GP            
Sbjct: 49   RGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGI 108

Query: 570  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG-----PQGPP 624
            PG  G+PG RG PG DG  G  G  G  G  G+ GL G PG  G +G +G     P    
Sbjct: 109  PGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK 168

Query: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP- 683
            G  GD G+ G DG  GP+G PG  G  G  GP G  G PG PG      P GP GNMG  
Sbjct: 169  GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG------PLGPDGNMGLG 222

Query: 684  -QGEPGPPGQQGNPGPQGLPGPQGPIG----PPGEKGPQGKPGLAGLPGADGPPGHPG-- 736
             QGE G  G  G PGP G P   G +     P G+KG +G+PG  G PG  GPPG PG  
Sbjct: 223  FQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLG 282

Query: 737  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 796
              G+ GEKG  G PG       PGPRG  G++GV+G  G +G+KG  GFPG  G  G++G
Sbjct: 283  TTGEKGEKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 336

Query: 797  DRGEVGQIGP-----------RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 845
             +G++G  GP            G  G  G  G  G  GD G  G  G  G  G+P L G 
Sbjct: 337  QKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGV 396

Query: 846  PGRQGPKGSTGFPGFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG-------------- 889
            PG  GP+G   FPG  G  G  G    G AG PG  G  GP GP G              
Sbjct: 397  PGALGPQG---FPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNK 453

Query: 890  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPG 949
              G  G  G+ GPKG  G  G  G  G     G     G PG  GPPGP G  GLPG  G
Sbjct: 454  ESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKG 513

Query: 950  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE------RGHPGPPGPPGEQGLPGAAG 1003
             RG+ G  G  GP G  G+VGP GP+G  G  GE      +G PG  G  G QG  G  G
Sbjct: 514  ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 573

Query: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG-----GEGPQGPPGPVGS 1058
            + G  G PG  G+ G  G  G +GFPGE+GLPG  G  G  G     G G  G PGP G 
Sbjct: 574  EPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGL 632

Query: 1059 PGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115
            PG++G  G  G  GLPG  G   P   PG  G  G PG  G  GP G  G+ G  G PG 
Sbjct: 633  PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 692

Query: 1116 AGPAGSPGEDG--DKGEI-GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG------ 1166
            +G  G PG  G     E+ G PG +G KG  G  G PG  GL G +G+PG+ G       
Sbjct: 693  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 752

Query: 1167 -----DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221
                 +G PG +G QG+ G KG  G  G PG  G  G  GL GP GE+G  G  G +G P
Sbjct: 753  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 812

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281
            G PG  GP G  G  G  G PG  G  G  G+KG  G+ G PG   + G+ G KG  G  
Sbjct: 813  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 872

Query: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341
            G  G  G+ G PG  G P   GPKG  G VGF G PG PG PG      + G +G  G P
Sbjct: 873  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG------IPGTRGLKGIP 926

Query: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ---------GEKGAKGEAGAEGPPGKT 1392
            G  G  GPSG AG PG  G RG PG  G    +         G+KG++G AG+ G PG  
Sbjct: 927  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 984

Query: 1393 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1452
             P G +G AG+PGP GL G PG  G   + G +G+ GPPG MG  GLPGLKG  G  G  
Sbjct: 985  -PRGDKGEAGRPGPPGLPGAPGLPGI--IKGVSGKPGPPGFMGIRGLPGLKGSSGITGFP 1041

Query: 1453 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGP 1508
            G P      G  G QG +G  GLPG  G PG KGD G    I G  GP G PG  G  G 
Sbjct: 1042 GMP------GESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1095

Query: 1509 QGP---------KGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
            +G           GNKG  G  G  GD GLPG PG PG  G
Sbjct: 1096 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1136



 Score =  743 bits (1919), Expect = 0.0
 Identities = 484/1132 (42%), Positives = 562/1132 (49%), Gaps = 104/1132 (9%)

Query: 403  PGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL 458
            PG     DI    I+G+    G  G  G KG+  +      + GP G  G   + G PG 
Sbjct: 344  PGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQG----LRGPSGVPGLPALSGVPGA 399

Query: 459  QGPTGPPGDPGDRGPPGRP-----GLPGADGLPGPPG----------TMLM------LPF 497
             GP G PG  GD+G PGR      GLPG DGLPGPPG          T  +       P 
Sbjct: 400  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 459

Query: 498  RYGGDGSKGPT-ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556
              G  G KG   +   +  +        +   GPPG  G  G  G +G PG  GA+G+ G
Sbjct: 460  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 519

Query: 557  DPGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGF---------DG 604
              G QGP G  G   P GP+G  GK+G P     +GMPG+ G  G +GF         DG
Sbjct: 520  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 579

Query: 605  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 664
            +PGLPG  G  G+ G QG PG  G  G+ GE G  GP GLPG   P GL GPRG PG  G
Sbjct: 580  VPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLP-GLPGPRGLPGDKG 637

Query: 665  QPGMAGVDGPPGPKG---------NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG 715
            + G+ G  G PG KG         + GP G PG PG  G  G +GLPG  G  G  G KG
Sbjct: 638  KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 697

Query: 716  PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG-----V 770
              G PGL  LP   G PG  G++G  G  G  G  G  G IG PG  G KGA G      
Sbjct: 698  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAE 757

Query: 771  RGLKGSKGEKGEDGFPGFKGDMGL---KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827
             G  G +G +G  G  GF GD GL   KG  G+ G +GP+GE G  G  G+ G  G PG 
Sbjct: 758  NGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGS 817

Query: 828  SGQAGEKGKLGVPGLPGYPG---RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884
            SG  G KGK G+PG PG+PG     G KG+ G  G PG+  +KG  G+ G PG  G  G 
Sbjct: 818  SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 877

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGP---PGPPGERGPQGPQGPVGFPGPKGPPGPPGK 941
             G  GS G  G     GPKG  G  G    PG PG  G  G +G  G PG  G  GP G+
Sbjct: 878  KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGR 937

Query: 942  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001
             G PG  G RG  G  G   P  P   +  +G  G  G  G  G PGP G  GE G PG 
Sbjct: 938  AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 997

Query: 1002 AGKEGAKGDPGP-QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
             G  GA G PG  +G+SGK GP G   F G RGLPG +G+ G+ G  G    PG  GS G
Sbjct: 998  PGLPGAPGLPGIIKGVSGKPGPPG---FMGIRGLPGLKGSSGITGFPGM---PGESGSQG 1051

Query: 1061 ERGSAGTAGPIGLPGRPGPQGPP----GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116
             RGS G  G  GLPG  G  G      G  G KG PGE G +G  GRDG+ G +G PG  
Sbjct: 1052 IRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNK 1111

Query: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG---PVGAPGIAGGDGEPGPR 1173
            G  G  G  GD G  G PG  G  G +GE G PG  G QG   P+G+PG+ G  G PG  
Sbjct: 1112 GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFP 1171

Query: 1174 GQQGMFGQKGDEGARGFPGPP--GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231
            G  G+ G  G +G  G PGP   G  G  GLPGP GEKG  G +G +G PG PG RG +G
Sbjct: 1172 GLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKG 1229

Query: 1232 PNGADGPQGPPGSVGSVGGVGEK---GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288
              G  G QGP G  G+ G        G+PG+ G PG  GE G  GP G  G  G +   G
Sbjct: 1230 DRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQG 1289

Query: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
              G PG  G PG  GPKG+ G  GF G PG  G  G  G+ G  G  G+ G PG PG PG
Sbjct: 1290 DTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPG 1349

Query: 1349 PSGEAGPPGPPGKRG-------------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1395
              G+AGP G  G +G             PPG  G  G  G  G  G+ GA+GP G  G  
Sbjct: 1350 MKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSK 1409

Query: 1396 GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKG 1444
            G  G  GK GP GL G PG +G+ GLPG  G    +G PG  GP G+PG+ G
Sbjct: 1410 GLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1461



 Score =  668 bits (1723), Expect = 0.0
 Identities = 436/1071 (40%), Positives = 516/1071 (48%), Gaps = 134/1071 (12%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAV-----------VEPGMLV 440
            P  PP+ EF      ET+      +G  G  GE+G KG   +            + G+  
Sbjct: 437  PPGPPSPEF------ETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 490

Query: 441  EGPPG---PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LML 495
             GPPG   P GP G++G PGL+G  G  G  G +GP G PGL G  G  GP G     +L
Sbjct: 491  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 550

Query: 496  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR-----PGPVGGPGSSG 550
                G  G +G   S  +     I +  +  + G PG  GL G      PG  G PG  G
Sbjct: 551  STIQGMPGDRGD--SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPG 608

Query: 551  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---------PGAKGDRG 601
             KG  G PG  G  G+ G PGP G PG +G+ G  G +G+PG          PG+ G  G
Sbjct: 609  EKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 667

Query: 602  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 661
            F G PG PG KG RG  G  G PG  G  G  G  G +    LPG  GPRG  G  G PG
Sbjct: 668  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 727

Query: 662  APGQPGMAGVDGPPGPKGNMGPQG-----EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716
             PG+ G+ G+ G PG  G+ G  G     E G PG+QG  G  G  G  G  G PG KG 
Sbjct: 728  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 787

Query: 717  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776
             GKPGL G  G  G PG PG+ GQ G  G+ GP G +G  G PG  G  G  G  G KG+
Sbjct: 788  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 847

Query: 777  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836
            +G+KG  G    KG  GLKG  G  G +G +G  G  G  G       P  SG  GEKG 
Sbjct: 848  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGL------PALSGPKGEKGS 901

Query: 837  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP--------- 887
            +G  G PG PG  G  G+ G  G PG+ G+ G  G AG PG +G RG  GP         
Sbjct: 902  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 961

Query: 888  ---------RGSRGARGPTGKPGPKGTSGGDGPPGPPGE----------RGPQGPQGPVG 928
                     +GS+G+ G  G PGP+G  G  G PGPPG           +G  G  GP G
Sbjct: 962  MSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPG 1021

Query: 929  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-RGHP 987
            F G +G PG  G  G+ G PG  GE+G QG  G PG  G  G  G  G+ G   E  G P
Sbjct: 1022 FMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSP 1081

Query: 988  GPPGPPGEQGLPGAAGKEGAKGD---PGPQGISGKDGPAGLRGFPGERGLPGA---QGAP 1041
            GP G PGE G  G  G++G  G+   PG +G  GK G +G  G PG  G PG    +G P
Sbjct: 1082 GPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEP 1141

Query: 1042 GLKGGEGPQGPPGPVGSPG---------------------ERGSAGTAGPIGLPGRPGPQ 1080
            GL G  G QG  GP+GSPG                      +G+ GT GP  + G PGP 
Sbjct: 1142 GLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPA 1200

Query: 1081 GPPGPAGEKGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK------GEIGE 1133
            G PGP GEKG PG   G  G  G  G +G  G PG  GPAG PG  G        G+ G+
Sbjct: 1201 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGD 1260

Query: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193
            PG+ G  G++G  GP GPPG  GP    G  G  G PG  G +G    KGD+G  GF G 
Sbjct: 1261 PGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG---PKGDQGIPGFSGL 1317

Query: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG------------- 1240
            PG +GL+G+ G PG  G  G VGP G PG PG +G  GP G+ G QG             
Sbjct: 1318 PGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV 1377

Query: 1241 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1300
            PPG +G     G  G PG  G+PG  G  G+ G KG  G  G+ GP G  GPPGA G PG
Sbjct: 1378 PPGPLGL---PGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1434

Query: 1301 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351
              G +G PG  G PG  GP G PG  GQ    G         +  PP P G
Sbjct: 1435 LPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1485



 Score =  667 bits (1721), Expect = 0.0
 Identities = 420/977 (42%), Positives = 486/977 (49%), Gaps = 115/977 (11%)

Query: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720
            GA G+PG  G+ GP GP      QG  G  G  G  G +G PG  GP GP G+KGP G P
Sbjct: 47   GARGRPGPIGIQGPTGP------QGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVP 100

Query: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780
            G  G+   +G PGHPG+ G  G  G  G  G QG +G+PGP G  G  G  GL G KG K
Sbjct: 101  GFLGI---NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSK 157

Query: 781  GED-----GFPGFKGDMGLKGDRGEVGQIGPRGEDG---PEGPKGRAGPTGDPGPSGQAG 832
            G+       F G KGD GL G  G  G  G  G  G   P GP G  GP G PGP G  G
Sbjct: 158  GDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 217

Query: 833  E-----KGKLGVPGLPGYPGRQGPKGSTG---FPGFPGANGEKGARGVAGKPGPRGQRGP 884
                  +G+ GV G  G PG  GP  STG   F GFP     KG +G  G+PGP+G  G 
Sbjct: 218  NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPKGFPGI 272

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944
            +GP G  G  G TG+ G KG  G  G PGP G  G +G QGP G  G KG  G PG +G 
Sbjct: 273  SGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF 331

Query: 945  PGHPGQRGETGFQGK-----------TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993
             G  GQ+G+ G  G            +G PG  GV G  G  G+ G  G RG  G PG P
Sbjct: 332  QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLP 391

Query: 994  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG----------- 1042
               G+PGA G +G  G  G QG  G+    G  G PG  GLPG  G PG           
Sbjct: 392  ALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 450

Query: 1043 ---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093
                     L+G +GP+G  G  G  G+ G     G +   G PG  GPPGP G  G PG
Sbjct: 451  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 510

Query: 1094 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI------GEPGQKGSKGDKGENG 1147
             KG +G  G  G QGP G PG  GP G  G  G KGE       G PG +G  G +G  G
Sbjct: 511  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 570

Query: 1148 PPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1205
              G PG  G  G PG+ G  GDG  G  G++G+ G  G++G  G PG PG  GL GLPGP
Sbjct: 571  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGP 629

Query: 1206 ---PGEKGENGDVGPMGPPGP---------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1253
               PG+KG++G  G  G PG          PG  GP G  G  G  GP GS G  G  G+
Sbjct: 630  RGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQ 689

Query: 1254 KGEPGEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307
             G  G  G PG PG        G  GP+GE+G  G  G PG  G PG  G PG  G KG 
Sbjct: 690  PGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGA 749

Query: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG------QPGPPGPSGEAGPPGPPGK 1361
             G + F  + G PGE G  G  G  G  G+ G PG      +PG  GP GE G PG PG+
Sbjct: 750  TGDI-FGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 808

Query: 1362 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL---RGIPGPVGE 1418
             G PG  G+ G  G KG  G  GA G PG +G  G +G  GK GP G    +G+PG  G 
Sbjct: 809  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 868

Query: 1419 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
             G PG  G  G PG  G  GLP L G  G KG  G  G  G+ G PG  G +G +G+PG+
Sbjct: 869  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 928

Query: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP------KGNKGS---------TGPAGQ 1523
             G  G  G  G PG  G  G PGP G+P P+ P      KG+KGS          GP G 
Sbjct: 929  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 988

Query: 1524 KGDSGLPGPPGSPGPPG 1540
            KG++G PGPPG PG PG
Sbjct: 989  KGEAGRPGPPGLPGAPG 1005



 Score =  607 bits (1564), Expect = e-173
 Identities = 403/940 (42%), Positives = 464/940 (49%), Gaps = 161/940 (17%)

Query: 743  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            EKGA G PGP G  G  GP+G  G+ G+ GLKG      E GFPG  G  G KGD+G +G
Sbjct: 45   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG------ERGFPGLLGPYGPKGDKGPMG 98

Query: 803  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862
              G  G +G  G  G+ GP G PG  G  G +G +G PG  GYPG  GP      PG PG
Sbjct: 99   VPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP------PGLPG 152

Query: 863  ANGEKGA--------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 914
              G KG         +G+ G PG  G  G TGP+G+ G  G  G  GP G  G  GPPGP
Sbjct: 153  QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 212

Query: 915  PGE--------RGPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGF 956
             G         +G +G +G VG PGP GPP           P GK G  G PG +G   F
Sbjct: 213  LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKG---F 269

Query: 957  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE------QGLPGAAGKEGAKGD 1010
             G +GPPG  G+    G TGE G  GE+G PG PGP G       QG PG  GK+G  G 
Sbjct: 270  PGISGPPGFPGL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGF 325

Query: 1011 PGPQGISGKDGPAGLRGFPG--------------ERGLPGAQGAPGLKGGEGPQGPPGPV 1056
            PG  G  G +G  G  G PG                G PG  G PGLKG EG QG  GP 
Sbjct: 326  PGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPS 385

Query: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPG 1114
            G PG    +G      +PG  GPQG PG  G++G PG    G  G  GRDG+ GP G PG
Sbjct: 386  GVPGLPALSG------VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 439

Query: 1115 PAGP-----------AGSPGEDGDKGEIGEPGQKGSKGDKG----ENGPP--GPPGLQGP 1157
            P  P           +G PG  G++G  G  G KG KGD G    + G P  GPPG  GP
Sbjct: 440  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 499

Query: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG------------LQGLPGP 1205
             G  G+ G  G  G RG +G  G +G  GA G  GP GP G            +QG+PG 
Sbjct: 500  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 559

Query: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263
             G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G  GEKG PG  G P
Sbjct: 560  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 619

Query: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP------PGDDGPKGNPGPVGFPGDP 1317
            G  G  G+ GP+G  G+KG+ G PG  G PG+KG       PG  GP G PG  GFPG  
Sbjct: 620  GN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 678

Query: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQ------PGPPGPSGEAGPPG---PPGKRGPPGAA 1368
            G  G PG  GQ G  G KGE G PG       PG PGP GE G PG    PGK G PG  
Sbjct: 679  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 738

Query: 1369 GAEGRQGEKGAKGEA--------GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG---PVG 1417
            G+ G  G KGA G+         G +G  G TG  G  G +G PG +G+ G PG   P G
Sbjct: 739  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 798

Query: 1418 EQGLPGA---AGQDGPPGPMGP------------PGLPGLKGDPGSKG---EKGHPGLIG 1459
            E+G PG     GQ G PG  GP            PG PG+ G PG KG   +KG PG I 
Sbjct: 799  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 858

Query: 1460 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP------------PGPPGLPG 1507
              G PG +G  G+ GL G +GSPG+ G  G+P  +GP G             PG PG+PG
Sbjct: 859  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 918

Query: 1508 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547
             +G KG  GSTG  G  G +G PG  G  G PG V  P P
Sbjct: 919  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP 958



 Score =  556 bits (1433), Expect = e-158
 Identities = 365/885 (41%), Positives = 417/885 (47%), Gaps = 127/885 (14%)

Query: 404  GVPAETDITETSINGHGAYGEKGQKGEPAVVEP--GMLVEGPPGPAGPAGIMGPPGLQGP 461
            G+P    IT   I   G+YG  G  G P    P     + G PG  G +G  G PG  G 
Sbjct: 646  GLPGSKGITLPCIIP-GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 704

Query: 462  T------GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
                   G PG  G++G PG PGLPG DGLPG  G+        G  GSKG T     A+
Sbjct: 705  VHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSP-------GLPGSKGATGDIFGAE 757

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575
              A          G  G  GLTG  G +G  G  G KG  G PG  GP+G +G PG  G+
Sbjct: 758  NGA---------PGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 808

Query: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP------------ 623
             G+ G PG+ G  G+ G+ G  G  GF G+ G PG KG RG++GP G             
Sbjct: 809  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 868

Query: 624  PGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMAGVDGPPGP 677
            PG PG  G++G  G  G  GLP  +GP+G       +G  G PG PG PG  G+ G PG 
Sbjct: 869  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 928

Query: 678  KGNMGPQGEPGPPGQQG---NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734
             G MGP G  G PG++G   NPGP G+P P+ P+     KG +G  G AG  G  GP   
Sbjct: 929  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGP--- 985

Query: 735  PGKEGQSGEKGALGPPGPQGPIGYPGPRGV----------KGADGVRGLKGSKGEKGEDG 784
                   G+KG  G PGP G  G PG  G+           G  G+RGL G KG  G  G
Sbjct: 986  ------RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1039

Query: 785  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA-------GPTGDPGPSGQAGEKGK- 836
            FPG  G+ G +G RG  G  G  G  G +G  G+        GP G PG SG  G KG+ 
Sbjct: 1040 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1099

Query: 837  -----LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891
                 +G PG  G  G+ G  G  G PG PG  G  G RG  G PG  G +G  GP GS 
Sbjct: 1100 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1159

Query: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-----GPVGFPGPKGPP-------GPP 939
            G  GP G PG  G  G +G PG  G  G  GP      GP G PGPKG         G P
Sbjct: 1160 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1219

Query: 940  GKDGLPGHPGQRGETGFQGKTGPPG------PGGVVGPQGPTGETGPIGERGHP---GPP 990
            GK GL G  G RG  G QG  G PG      P  + G  G  G  G  GERG P   GPP
Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1279

Query: 991  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1050
            GPPG     G  G  G  G PGP+G  G  G  G  G PGE GL G +G PG  G  G  
Sbjct: 1280 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1339

Query: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QGPPGPAGEKGAPGEKGPQGPAGR 1103
            GPPG  G PG +G AG  G  GL G PG        Q PPGP    G PG  G  G  G 
Sbjct: 1340 GPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPL---GLPGIDGIPGLTGD 1396

Query: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1163
             G QGPVGL G  G  G PG+DG  G  G PG  G          PG PGLQGP   PG 
Sbjct: 1397 PGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGD---------PGLPGLQGP---PGF 1444

Query: 1164 AGGDGEPGPRGQQGMFGQKGDEG------ARGFPGPPGPIGLQGL 1202
             G  G+ GP G  GM GQ    G      ++    PP PIG+  L
Sbjct: 1445 EGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQL 1489



 Score =  504 bits (1299), Expect = e-142
 Identities = 336/831 (40%), Positives = 377/831 (45%), Gaps = 164/831 (19%)

Query: 866  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925
            E  A G      P G +  +G       +G  G+PGP G  G  GP G  G  G  G +G
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 77

Query: 926  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG 985
              GFPG  GP GP G  G  G PG  G  G  G  G PGP    GP G  G  G  G  G
Sbjct: 78   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPR---GPPGLDGCNGTQGAVG 134

Query: 986  HPGPPGPPGEQGLPGAAGKEGAKGDP--GPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1043
             PGP G PG  G PG  G++G+KGDP   P    G  G  GL   PG  G+ G QGAPG 
Sbjct: 135  FPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL---PGLDGITGPQGAPGF 191

Query: 1044 KGGEGPQGPPGPVGSPGERGSAGTAGPIGL-----------PGRPGPQGPPGPAGE---- 1088
             G  GP GPPG  G PG  G  G  G +GL            G PGP GPP   GE    
Sbjct: 192  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 251

Query: 1089 ---KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1145
               KG  G KG  GP G  G+ GP G PG  G  G  GE G+KG  G PG +G  G +G 
Sbjct: 252  GFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 310

Query: 1146 NGPPGPPGLQGPVGAPGIAG--------GD------------------GEPGPRGQQGMF 1179
             GPPG  G +G +G PG+ G        GD                  G PG  G  G+ 
Sbjct: 311  QGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLP 370

Query: 1180 GQKGDEGARGFPGP------------PGPIGLQGLPGPPGEKGENGDV------------ 1215
            G KGDEG +G  GP            PG +G QG PG  G++G  G              
Sbjct: 371  GLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 430

Query: 1216 --GPMGPPGPPGP-----------------RGPQGPNGADGPQGPPGSVGSV---GGVGE 1253
              GP GPPGPP P                 RG QGP G  G +G  G  G     GGV  
Sbjct: 431  LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 490

Query: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK-------- 1305
             G PGE G PGP G  G+ G KG RG++G  G  G AG PG  GP G  GPK        
Sbjct: 491  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 550

Query: 1306 ----------------------GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
                                  G PG  G PG PG PG PG  GQ G  G+KG  G PG+
Sbjct: 551  STIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGE 609

Query: 1344 PGPPGPSGEAGP--PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQ 1398
             G PGP G  G   PG PG RG PG  G +G  G++G  G  G   P   PG  GP G  
Sbjct: 610  KGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFP 669

Query: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---------GPPGLPGLKGDPGSK 1449
            G  G PGP+G RG+PG  G+ G  G+ G+ G PG +         GP G  GL G PG  
Sbjct: 670  GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP 729

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGD-----RGLPGTQ---------------GSPGAKGDGG 1489
            G+ G PG+IG  G PG +G  GD      G PG Q               G PG KG  G
Sbjct: 730  GKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 789

Query: 1490 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
             PG  GP G  G PG PG  G  G  GS+GP G KG SGLPG PG PG  G
Sbjct: 790  KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 840



 Score =  442 bits (1138), Expect = e-123
 Identities = 288/707 (40%), Positives = 334/707 (47%), Gaps = 143/707 (20%)

Query: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034
            T E    GE+ +  P G     G      ++GA+G PGP GI G  GP G  G  G  GL
Sbjct: 16   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 75

Query: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094
             G +G PGL G  GP+G  GP+G PG  G  G  G    PG+PGP+GPPG  G  G  G 
Sbjct: 76   KGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH---PGQPGPRGPPGLDGCNGTQGA 132

Query: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152
             G  GP G  G+ GP GLPG  G  G P       KG  G+PG  G  G  G  G PG P
Sbjct: 133  VGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFP 192

Query: 1153 GLQGPVGAPGIAGGDGEPGPRGQQGMF-----GQKGDEGARGFPGP-------------- 1193
            G  GP G PG+ G  G PGP G  G       G+KG +G  G PGP              
Sbjct: 193  GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMG 252

Query: 1194 -----------PGPIGLQGLPGPP-----GEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1237
                       PGP G  G+ GPP     G  GE G+ G  G PG PGPRGP G  G  G
Sbjct: 253  FPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQG 312

Query: 1238 PQGPPGSVGSVG--------GV-GEKGE---PGE-----------AGNPGPPGEAGVGGP 1274
            P G  G  G++G        G+ G+KG+   PG            +GNPG PG  G+ G 
Sbjct: 313  PPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGL 372

Query: 1275 KGERGEKGEAGP------PGAAGPPGAKGP---PGDDGPKGNPGPV-----------GFP 1314
            KG+ G +G  GP      P  +G PGA GP   PG  G +GNPG             G P
Sbjct: 373  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 432

Query: 1315 GDPGPPGEPGP-----------AGQDGVGGDKGEDGDPGQPGPPGPSG---------EAG 1354
            G PGPPG P P           +G  G+ G++G  G+ G  G  G SG           G
Sbjct: 433  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 492

Query: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQGPAGKPGP----- 1406
            PPG PG  GP G  G  G +G +G +G  GA+GP   PG  GP+GP GP GK G      
Sbjct: 493  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 552

Query: 1407 -EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-----------PGSKGEKGH 1454
             +G+ G  G  G QG  G  G+ G  G  G PGLPGL GD           PG  GEKGH
Sbjct: 553  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 612

Query: 1455 P--------GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG---DGGIPGPAGPLGPPGPP 1503
            P        GL GL GP G  G+KG  GLPG QG PG+KG      IPG  GP G PG P
Sbjct: 613  PGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTP 672

Query: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGP---------PGSPGPPGE 1541
            G PGP+G +G  G+ G  G  G  G PG          PG PGP GE
Sbjct: 673  GFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGE 719



 Score =  374 bits (959), Expect = e-103
 Identities = 238/548 (43%), Positives = 277/548 (50%), Gaps = 78/548 (14%)

Query: 1085 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP---AGSPGEDGDKGEIGEPGQKGSKG 1141
            P G +   G        G  G  GP+G+ GP GP    GS G  G KGE G PG  G  G
Sbjct: 30   PCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG 89

Query: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1201
             KG+ GP G PG    +G  GI G  G+PGPRG  G+ G  G +GA GFPGP G  GL G
Sbjct: 90   PKGDKGPMGVPGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLG 146

Query: 1202 LPGPPGEKGENGDVGPMGPPGP-PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260
             PG PG+KG  GD  P+  PG   G +G  G  G DG  GP G+ G  G VG  G PG  
Sbjct: 147  PPGLPGQKGSKGD--PVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQ 204

Query: 1261 GNPGPPGEAGVGGP-----KGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNP 1308
            G PGPPG  G  G      +GE+G KG+ G PG AGPP + G       P G  G KG P
Sbjct: 205  GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 264

Query: 1309 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368
            GP GFPG  GPPG PG  G  G  G+KGE G PG PGP GP G  G  GPPG++G  G  
Sbjct: 265  GPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTL 323

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGK-----------TGPVGPQGPAGKPGPEGLRGIPGPVG 1417
            G  G  G +G +G+ G  G PG            +G  G  G  G PG +G  GI G  G
Sbjct: 324  GFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRG 383

Query: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE-----KGHPGLIGLIGPP-------- 1464
              G+PG     G PG +GP G PGLKGD G+ G       G PG  GL GPP        
Sbjct: 384  PSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSP 443

Query: 1465 ------------------GEQGEKGDRGLPGTQGSPG-AKGDGGIP--GPAGPLGPPGP- 1502
                              GEQG KG+ GL G +G  G    DGG+P  GP G  GPPGP 
Sbjct: 444  EFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPW 503

Query: 1503 --PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560
               GLPG +G +G++GS G  G  G  GL GP G  GP G+  +  PILS+       +G
Sbjct: 504  GLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK--KGEPILST------IQG 555

Query: 1561 MQADADDN 1568
            M  D  D+
Sbjct: 556  MPGDRGDS 563



 Score =  103 bits (258), Expect = 1e-21
 Identities = 73/183 (39%), Positives = 83/183 (45%), Gaps = 27/183 (14%)

Query: 1382 EAGAEGPPGKTGPVGPQGPAGKPG--PE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG 1438
            E  A G      P G Q  +G     PE G RG PGP+G QG            P GP G
Sbjct: 18   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQG------------PTGPQG 65

Query: 1439 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1498
              G  G  G KGE+G PGL+G  GP G++G           G PG  G  GIPG  G  G
Sbjct: 66   FTGSTGLSGLKGERGFPGLLGPYGPKGDKGP---------MGVPGFLGINGIPGHPGQPG 116

Query: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1558
            P GPPGL G  G +G  G  GP G  G   L GPPG PG  G    P+    S K  +  
Sbjct: 117  PRGPPGLDGCNGTQGAVGFPGPDGYPG---LLGPPGLPGQKGSKGDPVLAPGSFKGMKGD 173

Query: 1559 EGM 1561
             G+
Sbjct: 174  PGL 176


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  830 bits (2145), Expect = 0.0
 Identities = 535/1293 (41%), Positives = 632/1293 (48%), Gaps = 175/1293 (13%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G  G+KG KG+P V+ PG       G  G  G+ G  G+ GP G PG PG  GP G PGL
Sbjct: 148  GLPGQKGSKGDP-VLAPGSF----KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGL 202

Query: 480  PGADGLPGPPGTMLMLPFRYGGD----------GSKGPTISAQEAQAQAILQQARIALRG 529
             G  G PGP G    +   + G+          G  GP  S  E +      + +   +G
Sbjct: 203  QGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGF-PKGKKGSKG 261

Query: 530  PPGPMGLTGRPGPVGGPG--SSGAKGESGD------PGPQGP---RGVQGPPGPTGKPGK 578
             PGP G  G  GP G PG  ++G KGE G+      PGP+GP    GVQGPPG  GK G 
Sbjct: 262  EPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT 321

Query: 579  RGRPGADGGRGMPGEPG-----------------AKGDRGFDGLPGLPGDKGHRGERGPQ 621
             G PG +G +G+ G+ G                   G+ G  G+PGLPG KG  G +G +
Sbjct: 322  LGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLR 381

Query: 622  GPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 681
            GP G PG   + G  G +GP+G PG  G +G  G R T GA G PG  G+ GPPGP G  
Sbjct: 382  GPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPP 440

Query: 682  GPQ-----------GEPGPPGQQGNPGPQGLPGPQGP------------IGPPGEKGPQG 718
             P+           G PG  G+QG  G  GL G +G              GPPGE GP G
Sbjct: 441  SPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPG 500

Query: 719  KPGLAGLPGADGPPGHPGKEGQSGEKGA------LGPPGPQGPIGYP------GPRGVKG 766
              GL GLPG  G  G  G  G  G  GA      LGP GP+G  G P      G  G +G
Sbjct: 501  PWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRG 560

Query: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826
              G +G +G  GE G+DG PG  G  GL GD G+ G  G +G  G  G KG  GP G PG
Sbjct: 561  DSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGEKGHPGPPGLPG 619

Query: 827  --------PSGQAGEKGKLGVPG---LPG---------YPGRQGPKGSTGFPGFPGANGE 866
                    P G  G+KGK G+PG   LPG          PG  GP G  G PGFPG  G 
Sbjct: 620  NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 679

Query: 867  KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 926
            +G  G  G+PG  G +G  G  G        G PGP+G  G  G PG PG+ G  G  G 
Sbjct: 680  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 739

Query: 927  VGFPGPKGP-----------PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPT 975
             G PG KG            PG  G  GL GH G  G++G  G  G  G  G++GP+G  
Sbjct: 740  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 799

Query: 976  GETGPIGERGHPGPPGPPG------EQGLPGAAGKEGAKGDPGPQGISGKDGPAGL---R 1026
            G  G  G+ G PG PG  G      + GLPGA G  G  G PG +G  GK GP G    +
Sbjct: 800  GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKK 859

Query: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1086
            G PG +GLPG  G  GLKG  G  G  G     G +G  G+ G +G PG PG  G PG  
Sbjct: 860  GLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTR 919

Query: 1087 GEKGAPGEKGPQGPAGRDGVQG---------PVGLPGPAGPAGS---PGEDGDKGEIGEP 1134
            G KG PG  G  GP+GR G  G         PVG+P P  P  +    G+ G +G  G  
Sbjct: 920  GLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSN 979

Query: 1135 GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG-DGEPGP---RGQQGMFGQKGDEGARGF 1190
            G  G +GDKGE G PGPPGL G  G PGI  G  G+PGP    G +G+ G KG  G  GF
Sbjct: 980  GFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1039

Query: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGP-------PGPPGPRGPQGPNGADGPQGPPG 1243
            PG PG  G QG+ G PG  G +G  G  G         G PGP+G  G +G  G +G  G
Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099

Query: 1244 SVGSVGGVGEKGEPG------EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGP---PG 1294
             +G++G  G KGE G      + G PG PG  GV G +GE G  G +G  GA GP   PG
Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159

Query: 1295 AKGP------PGDDGPKGNPGPVGFPGDPGPP--GEPGPAGQDGVGGDKGEDG-DPGQPG 1345
              GP      PG  G  G PG  G  G PGP   G PGPAG  G  G+KG  G   G PG
Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPG 1219

Query: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405
             PG  G+ G  G PG +GP G  GA G        G+ G  G PG  G  G  GPAG PG
Sbjct: 1220 KPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPG 1279

Query: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL---IG 1462
            P G     G  G+ G PG  G  GP G  G PG  GL G+ G KG +G PG +G    +G
Sbjct: 1280 PPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVG 1339

Query: 1463 PPGEQGEKGDRGLPGTQGSPGAKGDGG-------IPGPAGPLGPPGPPGLPGPQGPKGNK 1515
            PPG+ G  G +G  G +GS G +GD G       +  P GPLG PG  G+PG  G  G +
Sbjct: 1340 PPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQ 1399

Query: 1516 GSTGPAGQKGDSGLPG---PPGSPGPPGEVIQP 1545
            G  G  G KG  G+PG   P G PGPPG +  P
Sbjct: 1400 GPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDP 1432



 Score =  819 bits (2116), Expect = 0.0
 Identities = 548/1326 (41%), Positives = 635/1326 (47%), Gaps = 209/1326 (15%)

Query: 420  GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479
            G+ G  G KGE     PG+L  GP GP G  G MG PG  G  G PG PG  GP G PGL
Sbjct: 67   GSTGLSGLKGERGF--PGLL--GPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGL 122

Query: 480  ------PGADGLPGPPG--TMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 531
                   GA G PGP G   +L  P   G  GSKG  + A  +            ++G P
Sbjct: 123  DGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK---------GMKGDP 173

Query: 532  GPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK--RGRPGADGGRG 589
            G  GL G  GP G PG  GA G +G PG QGP G  GP GP G  G   +G  G  G  G
Sbjct: 174  GLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVG 233

Query: 590  MP---GEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP---GPPGDDGM--RGEDGEIGP 641
            +P   G P + G+  F G P   G KG +GE GP+G P   GPPG  G+   GE GE G 
Sbjct: 234  LPGPAGPPPSTGELEFMGFP--KGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGE 291

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGE------PGP------ 689
            +G+PG  GPRG +G  G  G PGQ G  G  G PG  G  G +G+      PGP      
Sbjct: 292  KGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDI 351

Query: 690  -----PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG---LAGLPGADGPPGHPGKEGQS 741
                  G  G+PG  GLPG +G  G  G +GP G PG   L+G+PGA GP G PG +G  
Sbjct: 352  DGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQ 411

Query: 742  GEKGAL--------------GPPGPQGP--------------IGYPGPRGVKGADGVRGL 773
            G  G                GPPGP GP               G+PG RG +G  G  GL
Sbjct: 412  GNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGL 471

Query: 774  KGSKGEK---------------GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 818
            KG KG+                GE G PG  G +GL G +G  G  G  G  GP G  G 
Sbjct: 472  KGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL 531

Query: 819  AGPTGDPGPSGQAGE---------------KGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
             GP G  GP G+ GE                G  G  G+ G PG+ G  G  G PG PG 
Sbjct: 532  VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGD 591

Query: 864  NGE--KGARGVAGKPGPRGQRGPTG--PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERG 919
             G+   G +G+ G PG +G  GP G    G  G  GP G PG KG  G  G  G PG +G
Sbjct: 592  GGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKG 651

Query: 920  ------PQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQG 973
                    G  GP GFPG  G PGP G  GLPG PGQ G +G +G+  P  PG V  P+ 
Sbjct: 652  ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGE--PGSPGLVHLPEL 709

Query: 974  PTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG-----ISGKDGPAGLRGF 1028
            P G  GP GE+G PG PG PG+ GLPG  G  G  G  G  G      +G  G  GL+G 
Sbjct: 710  P-GFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGL 768

Query: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
             G +G  G  G PGLK   G  G PG +G  GERGS GT G +G PG PG  GP G  G+
Sbjct: 769  TGHKGFLGDSGLPGLK---GVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGK 825

Query: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGP 1148
             G PG  G  G +G  G +G  G  GP G     G  G KG  G PG  G KG  G  G 
Sbjct: 826  SGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGV 885

Query: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGE 1208
             G P L GP G  G  G  G PG  G  G+    G  G +G PG  G +G  G  G PGE
Sbjct: 886  AGLPALSGPKGEKGSVGFVGFPGIPGLPGI---PGTRGLKGIPGSTGKMGPSGRAGTPGE 942

Query: 1209 KGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268
            KG+ G+ GP+   G P PR P       G +G  GS GS G  G +G+ GEAG PGPPG 
Sbjct: 943  KGDRGNPGPV---GIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGL 999

Query: 1269 AGVGGPKG-ERGEKGEAGPP---GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324
             G  G  G  +G  G+ GPP   G  G PG KG  G  G  G PG  G  G  G PG PG
Sbjct: 1000 PGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1059

Query: 1325 PAGQDGVGGDKGE----DGDPGQPGPPGPSGEAGPPGP---------PGKRGPPGAAGAE 1371
             +G  G+ GD G+     G PG  G PG SG  G  G          PG +G  G  G  
Sbjct: 1060 ASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVS 1119

Query: 1372 GRQGEKGA---------KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLP 1422
            G  G  GA         +GE G  G  G  G +GP G  G  GP+G  G PG  G  GLP
Sbjct: 1120 GDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLP 1179

Query: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL-IGLIGPPGEQGEKGDRGLPGTQ-- 1479
            G  G  G PGP    G+PG  G PG KGEKG+PG+ IG  G PG +G+KGDRG PG Q  
Sbjct: 1180 GTKGTHGTPGP-SITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGP 1238

Query: 1480 ----------------------GSPGAKGDGGIPGPAGPLGPPGP------------PGL 1505
                                  G PG  G+ G PGPAGP GPPGP            PG+
Sbjct: 1239 AGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGI 1298

Query: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP---GPPGEVIQP----LPILSSKKTRRHT 1558
            PGP+GPKG++G  G +G  G+ GL G  G P   G PG+V  P     P +  K   R +
Sbjct: 1299 PGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGS 1358

Query: 1559 EGMQAD 1564
             G+Q D
Sbjct: 1359 SGLQGD 1364



 Score =  761 bits (1966), Expect = 0.0
 Identities = 484/1121 (43%), Positives = 553/1121 (49%), Gaps = 141/1121 (12%)

Query: 528  RGPPGPMGLTGRPGPVGGPGS---SGAKGESGDPG---PQGPRGVQGP------------ 569
            RG PGP+G+ G  GP G  GS   SG KGE G PG   P GP+G +GP            
Sbjct: 48   RGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGI 107

Query: 570  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERG-----PQGPP 624
            PG  G+PG RG PG DG  G  G  G  G  G+ GL G PG  G +G +G     P    
Sbjct: 108  PGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFK 167

Query: 625  GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGP- 683
            G  GD G+ G DG  GP+G PG  G  G  GP G  G PG PG      P GP GNMG  
Sbjct: 168  GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPG------PLGPDGNMGLG 221

Query: 684  -QGEPGPPGQQGNPGPQGLPGPQGPIG----PPGEKGPQGKPGLAGLPGADGPPGHPG-- 736
             QGE G  G  G PGP G P   G +     P G+KG +G+PG  G PG  GPPG PG  
Sbjct: 222  FQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLG 281

Query: 737  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 796
              G+ GEKG  G PG       PGPRG  G++GV+G  G +G+KG  GFPG  G  G++G
Sbjct: 282  TTGEKGEKGEKGIPG------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEG 335

Query: 797  DRGEVGQIGP-----------RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY 845
             +G++G  GP            G  G  G  G  G  GD G  G  G  G  G+P L G 
Sbjct: 336  QKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGV 395

Query: 846  PGRQGPKGSTGFPGFPGANGEKGAR--GVAGKPGPRGQRGPTGPRG-------------- 889
            PG  GP+G   FPG  G  G  G    G AG PG  G  GP GP G              
Sbjct: 396  PGALGPQG---FPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNK 452

Query: 890  SRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPG 949
              G  G  G+ GPKG  G  G  G  G     G     G PG  GPPGP G  GLPG  G
Sbjct: 453  ESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKG 512

Query: 950  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE------RGHPGPPGPPGEQGLPGAAG 1003
             RG+ G  G  GP G  G+VGP GP+G  G  GE      +G PG  G  G QG  G  G
Sbjct: 513  ARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIG 572

Query: 1004 KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKG-----GEGPQGPPGPVGS 1058
            + G  G PG  G+ G  G  G +GFPGE+GLPG  G  G  G     G G  G PGP G 
Sbjct: 573  EPGKDGVPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGL 631

Query: 1059 PGERGSAGTAGPIGLPGRPGPQGP---PGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115
            PG++G  G  G  GLPG  G   P   PG  G  G PG  G  GP G  G+ G  G PG 
Sbjct: 632  PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 691

Query: 1116 AGPAGSPGEDG--DKGEI-GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGG------ 1166
            +G  G PG  G     E+ G PG +G KG  G  G PG  GL G +G+PG+ G       
Sbjct: 692  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGD 751

Query: 1167 -----DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPP 1221
                 +G PG +G QG+ G KG  G  G PG  G  G  GL GP GE+G  G  G +G P
Sbjct: 752  IFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQP 811

Query: 1222 GPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK 1281
            G PG  GP G  G  G  G PG  G  G  G+KG  G+ G PG   + G+ G KG  G  
Sbjct: 812  GTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNP 871

Query: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP 1341
            G  G  G+ G PG  G P   GPKG  G VGF G PG PG PG      + G +G  G P
Sbjct: 872  GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG------IPGTRGLKGIP 925

Query: 1342 GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ---------GEKGAKGEAGAEGPPGKT 1392
            G  G  GPSG AG PG  G RG PG  G    +         G+KG++G AG+ G PG  
Sbjct: 926  GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 983

Query: 1393 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEK 1452
             P G +G AG+PGP GL G PG  G   + G +G+ GPPG MG  GLPGLKG  G  G  
Sbjct: 984  -PRGDKGEAGRPGPPGLPGAPGLPGI--IKGVSGKPGPPGFMGIRGLPGLKGSSGITGFP 1040

Query: 1453 GHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----IPGPAGPLGPPGPPGLPGP 1508
            G P      G  G QG +G  GLPG  G PG KGD G    I G  GP G PG  G  G 
Sbjct: 1041 GMP------GESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1094

Query: 1509 QGP---------KGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
            +G           GNKG  G  G  GD GLPG PG PG  G
Sbjct: 1095 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1135



 Score =  743 bits (1919), Expect = 0.0
 Identities = 484/1132 (42%), Positives = 562/1132 (49%), Gaps = 104/1132 (9%)

Query: 403  PGVPAETDITETSINGH----GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL 458
            PG     DI    I+G+    G  G  G KG+  +      + GP G  G   + G PG 
Sbjct: 343  PGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQG----LRGPSGVPGLPALSGVPGA 398

Query: 459  QGPTGPPGDPGDRGPPGRP-----GLPGADGLPGPPG----------TMLM------LPF 497
             GP G PG  GD+G PGR      GLPG DGLPGPPG          T  +       P 
Sbjct: 399  LGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPG 458

Query: 498  RYGGDGSKGPT-ISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556
              G  G KG   +   +  +        +   GPPG  G  G  G +G PG  GA+G+ G
Sbjct: 459  LRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRG 518

Query: 557  DPGPQGPRGVQG---PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGF---------DG 604
              G QGP G  G   P GP+G  GK+G P     +GMPG+ G  G +GF         DG
Sbjct: 519  SGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG 578

Query: 605  LPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPG 664
            +PGLPG  G  G+ G QG PG  G  G+ GE G  GP GLPG   P GL GPRG PG  G
Sbjct: 579  VPGLPGLPGLPGDGG-QGFPGEKGLPGLPGEKGHPGPPGLPGNGLP-GLPGPRGLPGDKG 636

Query: 665  QPGMAGVDGPPGPKG---------NMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG 715
            + G+ G  G PG KG         + GP G PG PG  G  G +GLPG  G  G  G KG
Sbjct: 637  KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 696

Query: 716  PQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG-----V 770
              G PGL  LP   G PG  G++G  G  G  G  G  G IG PG  G KGA G      
Sbjct: 697  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAE 756

Query: 771  RGLKGSKGEKGEDGFPGFKGDMGL---KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 827
             G  G +G +G  G  GF GD GL   KG  G+ G +GP+GE G  G  G+ G  G PG 
Sbjct: 757  NGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGS 816

Query: 828  SGQAGEKGKLGVPGLPGYPG---RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884
            SG  G KGK G+PG PG+PG     G KG+ G  G PG+  +KG  G+ G PG  G  G 
Sbjct: 817  SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 876

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGP---PGPPGERGPQGPQGPVGFPGPKGPPGPPGK 941
             G  GS G  G     GPKG  G  G    PG PG  G  G +G  G PG  G  GP G+
Sbjct: 877  KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGR 936

Query: 942  DGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA 1001
             G PG  G RG  G  G   P  P   +  +G  G  G  G  G PGP G  GE G PG 
Sbjct: 937  AGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGP 996

Query: 1002 AGKEGAKGDPGP-QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG 1060
             G  GA G PG  +G+SGK GP G   F G RGLPG +G+ G+ G  G    PG  GS G
Sbjct: 997  PGLPGAPGLPGIIKGVSGKPGPPG---FMGIRGLPGLKGSSGITGFPGM---PGESGSQG 1050

Query: 1061 ERGSAGTAGPIGLPGRPGPQGPP----GPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116
             RGS G  G  GLPG  G  G      G  G KG PGE G +G  GRDG+ G +G PG  
Sbjct: 1051 IRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNK 1110

Query: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQG---PVGAPGIAGGDGEPGPR 1173
            G  G  G  GD G  G PG  G  G +GE G PG  G QG   P+G+PG+ G  G PG  
Sbjct: 1111 GEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFP 1170

Query: 1174 GQQGMFGQKGDEGARGFPGPP--GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231
            G  G+ G  G +G  G PGP   G  G  GLPGP GEKG  G +G +G PG PG RG +G
Sbjct: 1171 GLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPG-IG-IGAPGKPGLRGQKG 1228

Query: 1232 PNGADGPQGPPGSVGSVGGVGEK---GEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288
              G  G QGP G  G+ G        G+PG+ G PG  GE G  GP G  G  G +   G
Sbjct: 1229 DRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQG 1288

Query: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
              G PG  G PG  GPKG+ G  GF G PG  G  G  G+ G  G  G+ G PG PG PG
Sbjct: 1289 DTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPG 1348

Query: 1349 PSGEAGPPGPPGKRG-------------PPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPV 1395
              G+AGP G  G +G             PPG  G  G  G  G  G+ GA+GP G  G  
Sbjct: 1349 MKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSK 1408

Query: 1396 GPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ---DGPPGPMGPPGLPGLKG 1444
            G  G  GK GP GL G PG +G+ GLPG  G    +G PG  GP G+PG+ G
Sbjct: 1409 GLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1460



 Score =  668 bits (1723), Expect = 0.0
 Identities = 436/1071 (40%), Positives = 516/1071 (48%), Gaps = 134/1071 (12%)

Query: 393  PTSPPNEEFGPGVPAETDITETSINGH-GAYGEKGQKGEPAV-----------VEPGMLV 440
            P  PP+ EF      ET+      +G  G  GE+G KG   +            + G+  
Sbjct: 436  PPGPPSPEF------ETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 489

Query: 441  EGPPG---PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTM--LML 495
             GPPG   P GP G++G PGL+G  G  G  G +GP G PGL G  G  GP G     +L
Sbjct: 490  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 549

Query: 496  PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR-----PGPVGGPGSSG 550
                G  G +G   S  +     I +  +  + G PG  GL G      PG  G PG  G
Sbjct: 550  STIQGMPGDRGD--SGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPG 607

Query: 551  AKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE---------PGAKGDRG 601
             KG  G PG  G  G+ G PGP G PG +G+ G  G +G+PG          PG+ G  G
Sbjct: 608  EKGHPGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG 666

Query: 602  FDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 661
            F G PG PG KG RG  G  G PG  G  G  G  G +    LPG  GPRG  G  G PG
Sbjct: 667  FPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG 726

Query: 662  APGQPGMAGVDGPPGPKGNMGPQG-----EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716
             PG+ G+ G+ G PG  G+ G  G     E G PG+QG  G  G  G  G  G PG KG 
Sbjct: 727  LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGV 786

Query: 717  QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776
             GKPGL G  G  G PG PG+ GQ G  G+ GP G +G  G PG  G  G  G  G KG+
Sbjct: 787  HGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGT 846

Query: 777  KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836
            +G+KG  G    KG  GLKG  G  G +G +G  G  G  G       P  SG  GEKG 
Sbjct: 847  RGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGL------PALSGPKGEKGS 900

Query: 837  LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGP--------- 887
            +G  G PG PG  G  G+ G  G PG+ G+ G  G AG PG +G RG  GP         
Sbjct: 901  VGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 960

Query: 888  ---------RGSRGARGPTGKPGPKGTSGGDGPPGPPGE----------RGPQGPQGPVG 928
                     +GS+G+ G  G PGP+G  G  G PGPPG           +G  G  GP G
Sbjct: 961  MSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPG 1020

Query: 929  FPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE-RGHP 987
            F G +G PG  G  G+ G PG  GE+G QG  G PG  G  G  G  G+ G   E  G P
Sbjct: 1021 FMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSP 1080

Query: 988  GPPGPPGEQGLPGAAGKEGAKGD---PGPQGISGKDGPAGLRGFPGERGLPGA---QGAP 1041
            GP G PGE G  G  G++G  G+   PG +G  GK G +G  G PG  G PG    +G P
Sbjct: 1081 GPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEP 1140

Query: 1042 GLKGGEGPQGPPGPVGSPG---------------------ERGSAGTAGPIGLPGRPGPQ 1080
            GL G  G QG  GP+GSPG                      +G+ GT GP  + G PGP 
Sbjct: 1141 GLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPA 1199

Query: 1081 GPPGPAGEKGAPGEK-GPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK------GEIGE 1133
            G PGP GEKG PG   G  G  G  G +G  G PG  GPAG PG  G        G+ G+
Sbjct: 1200 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGD 1259

Query: 1134 PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGP 1193
            PG+ G  G++G  GP GPPG  GP    G  G  G PG  G +G    KGD+G  GF G 
Sbjct: 1260 PGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKG---PKGDQGIPGFSGL 1316

Query: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQG------------- 1240
            PG +GL+G+ G PG  G  G VGP G PG PG +G  GP G+ G QG             
Sbjct: 1317 PGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQV 1376

Query: 1241 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1300
            PPG +G     G  G PG  G+PG  G  G+ G KG  G  G+ GP G  GPPGA G PG
Sbjct: 1377 PPGPLGL---PGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPG 1433

Query: 1301 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351
              G +G PG  G PG  GP G PG  GQ    G         +  PP P G
Sbjct: 1434 LPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIG 1484



 Score =  667 bits (1721), Expect = 0.0
 Identities = 420/977 (42%), Positives = 486/977 (49%), Gaps = 115/977 (11%)

Query: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720
            GA G+PG  G+ GP GP      QG  G  G  G  G +G PG  GP GP G+KGP G P
Sbjct: 46   GARGRPGPIGIQGPTGP------QGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVP 99

Query: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780
            G  G+   +G PGHPG+ G  G  G  G  G QG +G+PGP G  G  G  GL G KG K
Sbjct: 100  GFLGI---NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSK 156

Query: 781  GED-----GFPGFKGDMGLKGDRGEVGQIGPRGEDG---PEGPKGRAGPTGDPGPSGQAG 832
            G+       F G KGD GL G  G  G  G  G  G   P GP G  GP G PGP G  G
Sbjct: 157  GDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 216

Query: 833  E-----KGKLGVPGLPGYPGRQGPKGSTG---FPGFPGANGEKGARGVAGKPGPRGQRGP 884
                  +G+ GV G  G PG  GP  STG   F GFP     KG +G  G+PGP+G  G 
Sbjct: 217  NMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFP-----KGKKGSKGEPGPKGFPGI 271

Query: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944
            +GP G  G  G TG+ G KG  G  G PGP G  G +G QGP G  G KG  G PG +G 
Sbjct: 272  SGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF 330

Query: 945  PGHPGQRGETGFQGK-----------TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPP 993
             G  GQ+G+ G  G            +G PG  GV G  G  G+ G  G RG  G PG P
Sbjct: 331  QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLP 390

Query: 994  GEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG----------- 1042
               G+PGA G +G  G  G QG  G+    G  G PG  GLPG  G PG           
Sbjct: 391  ALSGVPGALGPQGFPGLKGDQGNPGRT-TIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 449

Query: 1043 ---------LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093
                     L+G +GP+G  G  G  G+ G     G +   G PG  GPPGP G  G PG
Sbjct: 450  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 509

Query: 1094 EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI------GEPGQKGSKGDKGENG 1147
             KG +G  G  G QGP G PG  GP G  G  G KGE       G PG +G  G +G  G
Sbjct: 510  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 569

Query: 1148 PPGPPGLQGPVGAPGIAG--GDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGP 1205
              G PG  G  G PG+ G  GDG  G  G++G+ G  G++G  G PG PG  GL GLPGP
Sbjct: 570  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN-GLPGLPGP 628

Query: 1206 ---PGEKGENGDVGPMGPPGP---------PGPRGPQGPNGADGPQGPPGSVGSVGGVGE 1253
               PG+KG++G  G  G PG          PG  GP G  G  G  GP GS G  G  G+
Sbjct: 629  RGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQ 688

Query: 1254 KGEPGEAGNPGPPGEA------GVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307
             G  G  G PG PG        G  GP+GE+G  G  G PG  G PG  G PG  G KG 
Sbjct: 689  PGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGA 748

Query: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG------QPGPPGPSGEAGPPGPPGK 1361
             G + F  + G PGE G  G  G  G  G+ G PG      +PG  GP GE G PG PG+
Sbjct: 749  TGDI-FGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 807

Query: 1362 RGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL---RGIPGPVGE 1418
             G PG  G+ G  G KG  G  GA G PG +G  G +G  GK GP G    +G+PG  G 
Sbjct: 808  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 867

Query: 1419 QGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGT 1478
             G PG  G  G PG  G  GLP L G  G KG  G  G  G+ G PG  G +G +G+PG+
Sbjct: 868  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 927

Query: 1479 QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGP------KGNKGS---------TGPAGQ 1523
             G  G  G  G PG  G  G PGP G+P P+ P      KG+KGS          GP G 
Sbjct: 928  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGD 987

Query: 1524 KGDSGLPGPPGSPGPPG 1540
            KG++G PGPPG PG PG
Sbjct: 988  KGEAGRPGPPGLPGAPG 1004



 Score =  607 bits (1564), Expect = e-173
 Identities = 403/940 (42%), Positives = 464/940 (49%), Gaps = 161/940 (17%)

Query: 743  EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
            EKGA G PGP G  G  GP+G  G+ G+ GLKG      E GFPG  G  G KGD+G +G
Sbjct: 44   EKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG------ERGFPGLLGPYGPKGDKGPMG 97

Query: 803  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862
              G  G +G  G  G+ GP G PG  G  G +G +G PG  GYPG  GP      PG PG
Sbjct: 98   VPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGP------PGLPG 151

Query: 863  ANGEKGA--------RGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGP 914
              G KG         +G+ G PG  G  G TGP+G+ G  G  G  GP G  G  GPPGP
Sbjct: 152  QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 211

Query: 915  PGE--------RGPQGPQGPVGFPGPKGPPG----------PPGKDGLPGHPGQRGETGF 956
             G         +G +G +G VG PGP GPP           P GK G  G PG +G   F
Sbjct: 212  LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKG---F 268

Query: 957  QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE------QGLPGAAGKEGAKGD 1010
             G +GPPG  G+    G TGE G  GE+G PG PGP G       QG PG  GK+G  G 
Sbjct: 269  PGISGPPGFPGL----GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGF 324

Query: 1011 PGPQGISGKDGPAGLRGFPG--------------ERGLPGAQGAPGLKGGEGPQGPPGPV 1056
            PG  G  G +G  G  G PG                G PG  G PGLKG EG QG  GP 
Sbjct: 325  PGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPS 384

Query: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK--GPQGPAGRDGVQGPVGLPG 1114
            G PG    +G      +PG  GPQG PG  G++G PG    G  G  GRDG+ GP G PG
Sbjct: 385  GVPGLPALSG------VPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG 438

Query: 1115 PAGP-----------AGSPGEDGDKGEIGEPGQKGSKGDKG----ENGPP--GPPGLQGP 1157
            P  P           +G PG  G++G  G  G KG KGD G    + G P  GPPG  GP
Sbjct: 439  PPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGP 498

Query: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIG------------LQGLPGP 1205
             G  G+ G  G  G RG +G  G +G  GA G  GP GP G            +QG+PG 
Sbjct: 499  PGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGD 558

Query: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNG--ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263
             G+ G  G  G +G PG  G  G  G  G   DG QG PG  G  G  GEKG PG  G P
Sbjct: 559  RGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLP 618

Query: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP------PGDDGPKGNPGPVGFPGDP 1317
            G  G  G+ GP+G  G+KG+ G PG  G PG+KG       PG  GP G PG  GFPG  
Sbjct: 619  GN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPK 677

Query: 1318 GPPGEPGPAGQDGVGGDKGEDGDPGQ------PGPPGPSGEAGPPG---PPGKRGPPGAA 1368
            G  G PG  GQ G  G KGE G PG       PG PGP GE G PG    PGK G PG  
Sbjct: 678  GSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMI 737

Query: 1369 GAEGRQGEKGAKGEA--------GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPG---PVG 1417
            G+ G  G KGA G+         G +G  G TG  G  G +G PG +G+ G PG   P G
Sbjct: 738  GSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKG 797

Query: 1418 EQGLPGA---AGQDGPPGPMGP------------PGLPGLKGDPGSKG---EKGHPGLIG 1459
            E+G PG     GQ G PG  GP            PG PG+ G PG KG   +KG PG I 
Sbjct: 798  ERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIV 857

Query: 1460 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP------------PGPPGLPG 1507
              G PG +G  G+ GL G +GSPG+ G  G+P  +GP G             PG PG+PG
Sbjct: 858  KKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPG 917

Query: 1508 PQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547
             +G KG  GSTG  G  G +G PG  G  G PG V  P P
Sbjct: 918  TRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSP 957



 Score =  556 bits (1433), Expect = e-158
 Identities = 365/885 (41%), Positives = 417/885 (47%), Gaps = 127/885 (14%)

Query: 404  GVPAETDITETSINGHGAYGEKGQKGEPAVVEP--GMLVEGPPGPAGPAGIMGPPGLQGP 461
            G+P    IT   I   G+YG  G  G P    P     + G PG  G +G  G PG  G 
Sbjct: 645  GLPGSKGITLPCIIP-GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGL 703

Query: 462  T------GPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQ 515
                   G PG  G++G PG PGLPG DGLPG  G+        G  GSKG T     A+
Sbjct: 704  VHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSP-------GLPGSKGATGDIFGAE 756

Query: 516  AQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK 575
              A          G  G  GLTG  G +G  G  G KG  G PG  GP+G +G PG  G+
Sbjct: 757  NGA---------PGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQ 807

Query: 576  PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGP------------ 623
             G+ G PG+ G  G+ G+ G  G  GF G+ G PG KG RG++GP G             
Sbjct: 808  VGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGL 867

Query: 624  PGPPGDDGMRGEDGEIGPRGLPGEAGPRG------LLGPRGTPGAPGQPGMAGVDGPPGP 677
            PG PG  G++G  G  G  GLP  +GP+G       +G  G PG PG PG  G+ G PG 
Sbjct: 868  PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGS 927

Query: 678  KGNMGPQGEPGPPGQQG---NPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734
             G MGP G  G PG++G   NPGP G+P P+ P+     KG +G  G AG  G  GP   
Sbjct: 928  TGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGP--- 984

Query: 735  PGKEGQSGEKGALGPPGPQGPIGYPGPRGV----------KGADGVRGLKGSKGEKGEDG 784
                   G+KG  G PGP G  G PG  G+           G  G+RGL G KG  G  G
Sbjct: 985  ------RGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1038

Query: 785  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRA-------GPTGDPGPSGQAGEKGK- 836
            FPG  G+ G +G RG  G  G  G  G +G  G+        GP G PG SG  G KG+ 
Sbjct: 1039 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1098

Query: 837  -----LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891
                 +G PG  G  G+ G  G  G PG PG  G  G RG  G PG  G +G  GP GS 
Sbjct: 1099 GLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSP 1158

Query: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQ-----GPVGFPGPKGPP-------GPP 939
            G  GP G PG  G  G +G PG  G  G  GP      GP G PGPKG         G P
Sbjct: 1159 GLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAP 1218

Query: 940  GKDGLPGHPGQRGETGFQGKTGPPG------PGGVVGPQGPTGETGPIGERGHP---GPP 990
            GK GL G  G RG  G QG  G PG      P  + G  G  G  G  GERG P   GPP
Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1278

Query: 991  GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQ 1050
            GPPG     G  G  G  G PGP+G  G  G  G  G PGE GL G +G PG  G  G  
Sbjct: 1279 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1338

Query: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGP-------QGPPGPAGEKGAPGEKGPQGPAGR 1103
            GPPG  G PG +G AG  G  GL G PG        Q PPGP    G PG  G  G  G 
Sbjct: 1339 GPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPL---GLPGIDGIPGLTGD 1395

Query: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1163
             G QGPVGL G  G  G PG+DG  G  G PG  G          PG PGLQGP   PG 
Sbjct: 1396 PGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGD---------PGLPGLQGP---PGF 1443

Query: 1164 AGGDGEPGPRGQQGMFGQKGDEG------ARGFPGPPGPIGLQGL 1202
             G  G+ GP G  GM GQ    G      ++    PP PIG+  L
Sbjct: 1444 EGAPGQQGPFGMPGMPGQSMRVGYTLVKHSQSEQVPPCPIGMSQL 1488



 Score =  504 bits (1299), Expect = e-142
 Identities = 336/831 (40%), Positives = 377/831 (45%), Gaps = 164/831 (19%)

Query: 866  EKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQG 925
            E  A G      P G +  +G       +G  G+PGP G  G  GP G  G  G  G +G
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKG 76

Query: 926  PVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERG 985
              GFPG  GP GP G  G  G PG  G  G  G  G PGP    GP G  G  G  G  G
Sbjct: 77   ERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPR---GPPGLDGCNGTQGAVG 133

Query: 986  HPGPPGPPGEQGLPGAAGKEGAKGDP--GPQGISGKDGPAGLRGFPGERGLPGAQGAPGL 1043
             PGP G PG  G PG  G++G+KGDP   P    G  G  GL   PG  G+ G QGAPG 
Sbjct: 134  FPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGL---PGLDGITGPQGAPGF 190

Query: 1044 KGGEGPQGPPGPVGSPGERGSAGTAGPIGL-----------PGRPGPQGPPGPAGE---- 1088
             G  GP GPPG  G PG  G  G  G +GL            G PGP GPP   GE    
Sbjct: 191  PGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFM 250

Query: 1089 ---KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1145
               KG  G KG  GP G  G+ GP G PG  G  G  GE G+KG  G PG +G  G +G 
Sbjct: 251  GFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGV 309

Query: 1146 NGPPGPPGLQGPVGAPGIAG--------GD------------------GEPGPRGQQGMF 1179
             GPPG  G +G +G PG+ G        GD                  G PG  G  G+ 
Sbjct: 310  QGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLP 369

Query: 1180 GQKGDEGARGFPGP------------PGPIGLQGLPGPPGEKGENGDV------------ 1215
            G KGDEG +G  GP            PG +G QG PG  G++G  G              
Sbjct: 370  GLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 429

Query: 1216 --GPMGPPGPPGP-----------------RGPQGPNGADGPQGPPGSVGSV---GGVGE 1253
              GP GPPGPP P                 RG QGP G  G +G  G  G     GGV  
Sbjct: 430  LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 489

Query: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK-------- 1305
             G PGE G PGP G  G+ G KG RG++G  G  G AG PG  GP G  GPK        
Sbjct: 490  TGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPIL 549

Query: 1306 ----------------------GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343
                                  G PG  G PG PG PG PG  GQ G  G+KG  G PG+
Sbjct: 550  STIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQ-GFPGEKGLPGLPGE 608

Query: 1344 PGPPGPSGEAGP--PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQ 1398
             G PGP G  G   PG PG RG PG  G +G  G++G  G  G   P   PG  GP G  
Sbjct: 609  KGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFP 668

Query: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---------GPPGLPGLKGDPGSK 1449
            G  G PGP+G RG+PG  G+ G  G+ G+ G PG +         GP G  GL G PG  
Sbjct: 669  GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP 728

Query: 1450 GEKGHPGLIGLIGPPGEQGEKGD-----RGLPGTQ---------------GSPGAKGDGG 1489
            G+ G PG+IG  G PG +G  GD      G PG Q               G PG KG  G
Sbjct: 729  GKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHG 788

Query: 1490 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540
             PG  GP G  G PG PG  G  G  GS+GP G KG SGLPG PG PG  G
Sbjct: 789  KPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISG 839



 Score =  442 bits (1138), Expect = e-123
 Identities = 288/707 (40%), Positives = 334/707 (47%), Gaps = 143/707 (20%)

Query: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034
            T E    GE+ +  P G     G      ++GA+G PGP GI G  GP G  G  G  GL
Sbjct: 15   TEELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGL 74

Query: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094
             G +G PGL G  GP+G  GP+G PG  G  G  G    PG+PGP+GPPG  G  G  G 
Sbjct: 75   KGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH---PGQPGPRGPPGLDGCNGTQGA 131

Query: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSP--GEDGDKGEIGEPGQKGSKGDKGENGPPGPP 1152
             G  GP G  G+ GP GLPG  G  G P       KG  G+PG  G  G  G  G PG P
Sbjct: 132  VGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFP 191

Query: 1153 GLQGPVGAPGIAGGDGEPGPRGQQGMF-----GQKGDEGARGFPGP-------------- 1193
            G  GP G PG+ G  G PGP G  G       G+KG +G  G PGP              
Sbjct: 192  GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMG 251

Query: 1194 -----------PGPIGLQGLPGPP-----GEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1237
                       PGP G  G+ GPP     G  GE G+ G  G PG PGPRGP G  G  G
Sbjct: 252  FPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQG 311

Query: 1238 PQGPPGSVGSVG--------GV-GEKGE---PGE-----------AGNPGPPGEAGVGGP 1274
            P G  G  G++G        G+ G+KG+   PG            +GNPG PG  G+ G 
Sbjct: 312  PPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGL 371

Query: 1275 KGERGEKGEAGP------PGAAGPPGAKGP---PGDDGPKGNPGPV-----------GFP 1314
            KG+ G +G  GP      P  +G PGA GP   PG  G +GNPG             G P
Sbjct: 372  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 431

Query: 1315 GDPGPPGEPGP-----------AGQDGVGGDKGEDGDPGQPGPPGPSG---------EAG 1354
            G PGPPG P P           +G  G+ G++G  G+ G  G  G SG           G
Sbjct: 432  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 491

Query: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP---PGKTGPVGPQGPAGKPGP----- 1406
            PPG PG  GP G  G  G +G +G +G  GA+GP   PG  GP+GP GP GK G      
Sbjct: 492  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 551

Query: 1407 -EGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD-----------PGSKGEKGH 1454
             +G+ G  G  G QG  G  G+ G  G  G PGLPGL GD           PG  GEKGH
Sbjct: 552  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 611

Query: 1455 P--------GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG---DGGIPGPAGPLGPPGPP 1503
            P        GL GL GP G  G+KG  GLPG QG PG+KG      IPG  GP G PG P
Sbjct: 612  PGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTP 671

Query: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGP---------PGSPGPPGE 1541
            G PGP+G +G  G+ G  G  G  G PG          PG PGP GE
Sbjct: 672  GFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGE 718



 Score =  374 bits (959), Expect = e-103
 Identities = 238/548 (43%), Positives = 277/548 (50%), Gaps = 78/548 (14%)

Query: 1085 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP---AGSPGEDGDKGEIGEPGQKGSKG 1141
            P G +   G        G  G  GP+G+ GP GP    GS G  G KGE G PG  G  G
Sbjct: 29   PCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG 88

Query: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1201
             KG+ GP G PG    +G  GI G  G+PGPRG  G+ G  G +GA GFPGP G  GL G
Sbjct: 89   PKGDKGPMGVPGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLG 145

Query: 1202 LPGPPGEKGENGDVGPMGPPGP-PGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260
             PG PG+KG  GD  P+  PG   G +G  G  G DG  GP G+ G  G VG  G PG  
Sbjct: 146  PPGLPGQKGSKGD--PVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQ 203

Query: 1261 GNPGPPGEAGVGGP-----KGERGEKGEAGPPGAAGPPGAKG-------PPGDDGPKGNP 1308
            G PGPPG  G  G      +GE+G KG+ G PG AGPP + G       P G  G KG P
Sbjct: 204  GPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 263

Query: 1309 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368
            GP GFPG  GPPG PG  G  G  G+KGE G PG PGP GP G  G  GPPG++G  G  
Sbjct: 264  GPKGFPGISGPPGFPG-LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTL 322

Query: 1369 GAEGRQGEKGAKGEAGAEGPPGK-----------TGPVGPQGPAGKPGPEGLRGIPGPVG 1417
            G  G  G +G +G+ G  G PG            +G  G  G  G PG +G  GI G  G
Sbjct: 323  GFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRG 382

Query: 1418 EQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE-----KGHPGLIGLIGPP-------- 1464
              G+PG     G PG +GP G PGLKGD G+ G       G PG  GL GPP        
Sbjct: 383  PSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSP 442

Query: 1465 ------------------GEQGEKGDRGLPGTQGSPG-AKGDGGIP--GPAGPLGPPGP- 1502
                              GEQG KG+ GL G +G  G    DGG+P  GP G  GPPGP 
Sbjct: 443  EFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPW 502

Query: 1503 --PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560
               GLPG +G +G++GS G  G  G  GL GP G  GP G+  +  PILS+       +G
Sbjct: 503  GLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK--KGEPILST------IQG 554

Query: 1561 MQADADDN 1568
            M  D  D+
Sbjct: 555  MPGDRGDS 562



 Score =  103 bits (258), Expect = 1e-21
 Identities = 73/183 (39%), Positives = 83/183 (45%), Gaps = 27/183 (14%)

Query: 1382 EAGAEGPPGKTGPVGPQGPAGKPG--PE-GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPG 1438
            E  A G      P G Q  +G     PE G RG PGP+G QG            P GP G
Sbjct: 17   ELAAAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQG------------PTGPQG 64

Query: 1439 LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLG 1498
              G  G  G KGE+G PGL+G  GP G++G           G PG  G  GIPG  G  G
Sbjct: 65   FTGSTGLSGLKGERGFPGLLGPYGPKGDKGP---------MGVPGFLGINGIPGHPGQPG 115

Query: 1499 PPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHT 1558
            P GPPGL G  G +G  G  GP G  G   L GPPG PG  G    P+    S K  +  
Sbjct: 116  PRGPPGLDGCNGTQGAVGFPGPDGYPG---LLGPPGLPGQKGSKGDPVLAPGSFKGMKGD 172

Query: 1559 EGM 1561
             G+
Sbjct: 173  PGL 175


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  825 bits (2130), Expect = 0.0
 Identities = 537/1283 (41%), Positives = 614/1283 (47%), Gaps = 241/1283 (18%)

Query: 461  PTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAIL 520
            P+GP G  G+RG            LPGPPG+        G  G++G           A L
Sbjct: 332  PSGPKGGKGERG------------LPGPPGSK-------GEKGARGN--DCVRISPDAPL 370

Query: 521  QQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK-- 578
            Q A     GP G  G +G  GP G PGS+G KG+ G+ G  G +GV G PG  G+PG+  
Sbjct: 371  QCAE----GPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEIC 426

Query: 579  -------RGRPGADGGRGMPGEPGAKGDRGFDG--LPGLPGDKGHRGERGPQGPPGPPGD 629
                   +G PG  G  G+ GEPG  G  G  G  LPG PGD G        GPPGP GD
Sbjct: 427  VIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG--------GPPGPKGD 478

Query: 630  DGMRGEDGEIGPRGLPGEAGPRGLLGP--RGTPGAP-GQPGMAGVDGPPGPKGNMG-PQG 685
             G  G  G+ GP G PG+ G +G  G      P  P G     G+ G PGPKG  G P  
Sbjct: 479  KGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVP 538

Query: 686  EPGPPGQQGNPGPQGLP--------GPQGPIGPPGEKGPQGKPG--LAGLPGADGPPGHP 735
              G PG QG  G +G P        G Q  +   G  G  G PG  L GLPG  G PG  
Sbjct: 539  ARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLK 598

Query: 736  GKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA------------DG---VRGLKGSKGEK 780
            G++G  GE G  G PGP GP+G  G +G KG             DG   V  L G  GEK
Sbjct: 599  GEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEK 658

Query: 781  GEDGFPGF--------KGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 832
            GE G PGF         G+ GLKG +G+ G  G  G  G  G  G +G  G  GP+G  G
Sbjct: 659  GEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKG 718

Query: 833  EKGK---------------LGVPGLPGYPGRQGPKG-----STGFPGFPGANGEKGARGV 872
            EKG                 G PG PG  G QGP+G       G PG PG  G  G +GV
Sbjct: 719  EKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGV 778

Query: 873  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932
             G+PGP G RG  GP+G  GA    G PG +G  G  GPPGP GE+G QG  G  G  GP
Sbjct: 779  QGEPGPPG-RGVQGPQGEPGA---PGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGP 834

Query: 933  KGPPG-----PPGKDG---------LPGHPGQRGETGFQGKTGPPGPGGVV--GPQGPTG 976
             GPPG     PPG+DG          PG  G RGE G  G+   P  G ++  G  G  G
Sbjct: 835  VGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPG 894

Query: 977  -------ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK---------- 1019
                   + GP G  G PGPPGPPG  GL G  G  G  G PG     G           
Sbjct: 895  LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKS 954

Query: 1020 ---DGPAGLRGFPG---ERGLPGAQGAPGLKGGE-------------------------- 1047
               D   G R  PG   E+G  G QG PG+ G +                          
Sbjct: 955  ICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDP 1014

Query: 1048 ---GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1104
               G  G PGP G PG+RG  G  G  G PG PGP GPPG  G  G+PG  G QG  G  
Sbjct: 1015 GCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLT 1074

Query: 1105 GVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIA 1164
            G+ G  G PGP G  G PG  G  G  G  G++G  G  GE G PGPPG +G  G PG A
Sbjct: 1075 GLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPA 1134

Query: 1165 GGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGL---PGPPGEKGENGDVGPMGP- 1220
            G  GE GP+G  G  G +G +G  GFPGPPGP G  G    PGPPG + E G  G  GP 
Sbjct: 1135 GPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS 1194

Query: 1221 -----PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPK 1275
                 PGPPGP G QGP G DG  G  G  G  G  G  G PG  G PG  G+ G  G  
Sbjct: 1195 GLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLP 1254

Query: 1276 GERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVG--G 1333
            G +G+ G+ GPPG+ G PGA+G PG  GP+G PGP G  G PGPPG+PGPAG   VG  G
Sbjct: 1255 GPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKG 1314

Query: 1334 DKGEDGD------PGQPGPPG---PSGE------AGPPGPPGKRG------PPGAAGAEG 1372
            D+G  G+      PGQPGPPG   P GE      AG  GPPGK+G      P G  GA G
Sbjct: 1315 DRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAG 1374

Query: 1373 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP-- 1430
            ++G+ G KG AG  G PGK+G +GP GP G  G  G  G PGP G  GLPG  G  G   
Sbjct: 1375 QKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMV 1434

Query: 1431 ----------------------------PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1462
                                          PM     PG  G PG  G  G PG  G  G
Sbjct: 1435 NYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPG 1494

Query: 1463 PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKG--NKGSTGP 1520
             PG+ G +G +GLPG +G PG KG+ G  G  G  G  G PG PGPQGP G    G+TGP
Sbjct: 1495 LPGQIGREGRQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPGYGKMGATGP 1553

Query: 1521 AGQKGDSGLPGPPG---SPGPPG 1540
             GQ+G  G+PGPPG    PG  G
Sbjct: 1554 MGQQGIPGIPGPPGPMGQPGKAG 1576



 Score =  811 bits (2095), Expect = 0.0
 Identities = 525/1296 (40%), Positives = 600/1296 (46%), Gaps = 284/1296 (21%)

Query: 511  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG----- 565
            +Q+A+  A + Q   A   PP   G       +   G  G KGE G PGP G +G     
Sbjct: 298  SQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGAR 357

Query: 566  ---------------VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPG 610
                            +GP G  G+ G  G  G  G  G  G+ G KGD G  G+PG PG
Sbjct: 358  GNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPG 417

Query: 611  DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPR--GTPGAPGQPGM 668
              G  GE    GP G  GD G       +GP GL GE GP GL GP   G PG PG PG 
Sbjct: 418  RDGRPGEICVIGPKGQKGDPGF------VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG- 470

Query: 669  AGVDGPPGPKGNM---------GPQGEPGPPGQQGNPGPQ---------------GLPGP 704
                GPPGPKG+          GP G+PG PG +G  G                 GLPG 
Sbjct: 471  ----GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGK 526

Query: 705  QGPIGPPGE-------------KGPQGKP----------------------------GLA 723
             GP G PG+             KG +G+P                            GL 
Sbjct: 527  PGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLP 586

Query: 724  GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADG-------------- 769
            GLPG  G PG  G++G  GE G  G PGP GP+   GP G+KGA G              
Sbjct: 587  GLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPV---GPAGIKGAKGEPCEPCPALSNLQD 643

Query: 770  ----VRGLKGSKGEKGEDGFPGF--------KGDMGLKGDRGEVGQIGPRGEDGPEGPKG 817
                V  L G  GEKGE G PGF         G+ GLKG +G+ G  G  G  G  G  G
Sbjct: 644  GDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPG 703

Query: 818  RAGPTGDPGPSGQAGEKG---------------KLGVPGLPGYPGRQGPK-----GSTGF 857
             +G  G  GP+G  GEKG                 G PG PG  G QGP+     G  G 
Sbjct: 704  LSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQ 763

Query: 858  PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGE 917
            PG PG  G  G +GV G+PGP G RG  GP+G  GA    G PG +G  G  GPPGP GE
Sbjct: 764  PGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGA---PGLPGIQGLPGPRGPPGPTGE 819

Query: 918  RGPQGPQGPVGFPGPKGPP-----GPPGKD---------GLPGHPGQRGETGFQGKTGPP 963
            +G QG  G  G  GP GPP     GPPG+D         G PG  G RGE G  G+   P
Sbjct: 820  KGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP 879

Query: 964  GPGGVV--GPQGPTG-------ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ 1014
              G ++  G  G  G       + GP G  G PGPPGPPG  GL G  G  G  G PG  
Sbjct: 880  SQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939

Query: 1015 GISGK-------------DGPAGLRGFPG---ERGLPGAQGAPGLKGGE----------- 1047
               G              D   G R  PG   E+G  G QG PG+ G +           
Sbjct: 940  AELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLER 999

Query: 1048 ------------------GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEK 1089
                              G  G PGP G PG+RG  G  G  G PG PGP GPPG  G  
Sbjct: 1000 PRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAV 1059

Query: 1090 GAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1149
            G+PG  G QG  G  G+ G  G PGP G  G PG  G  G  G  G++G  G  GE G P
Sbjct: 1060 GSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP 1119

Query: 1150 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ---GLPGPP 1206
            GPPG +G  G PG AG  GE GP+G  G  G +G +G  GFPGPPGP G     G PGPP
Sbjct: 1120 GPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179

Query: 1207 GEKGENGDVGPMGP------PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260
            G + E G  G  GP      PGPPGP G QGP G DG  G  G  G  G  G  G PG  
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM 1239

Query: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320
            G PG  G+ G  G  G +G+ G+ GPPG+ G PGA+G PG  GP+G PGP G  G PGPP
Sbjct: 1240 GPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPP 1299

Query: 1321 GEPGPAGQDGVG--GDKGEDGD------PGQPGP---PGPSGE------AGPPGPPGKR- 1362
            G+PGPAG   VG  GD+G  G+      PGQPGP   PGP GE      AG  GPPGK+ 
Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359

Query: 1363 -----GPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVG 1417
                 GP G  GA G++G+ G KG AG  G PGK+G +GP GP G  G  G  G PGP G
Sbjct: 1360 FYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSG 1419

Query: 1418 EQGLPGAAGQDGP------------------------------PGPMGPPGLPGLKGDPG 1447
              GLPG  G  G                                 PM     PG  G PG
Sbjct: 1420 SPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPG 1479

Query: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPG 1507
              G  G PG  G  G PG+ G +G +GLPG +G PG KG+ G  G  G  G  G PG PG
Sbjct: 1480 KDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPG 1538

Query: 1508 PQGPK--GNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541
            PQGP   G  G+TGP GQ+G  G+PGPPG  G PG+
Sbjct: 1539 PQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGK 1574



 Score =  772 bits (1993), Expect = 0.0
 Identities = 501/1252 (40%), Positives = 577/1252 (46%), Gaps = 254/1252 (20%)

Query: 420  GAYGEKGQKGEPAVV----EPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPG 475
            G+ GEKG +G   V      P    EGP G  G +G +GP GL G TG  G  G++G  G
Sbjct: 349  GSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGG 408

Query: 476  RPGLPGADGLPGPPGTMLML-PFRYGGD-GSKGPTISAQEAQAQAILQQARIAL------ 527
              G+PG  G  G PG + ++ P    GD G  GP   A E     +     I L      
Sbjct: 409  IKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGD 468

Query: 528  -RGPPGP------MGLTGRPGPVGGPGSSGAKGESGDP---------GPQGPRGVQGPPG 571
              GPPGP       G+ G+ GP G PG  G KGE GDP         G Q   G+ G PG
Sbjct: 469  PGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPG 528

Query: 572  PTGKPG----KRGRPGADGGRGMPGEP-----------------GAKGDRGFD------- 603
            P G+PG     RG PG  G +G  GEP                 GA GD G         
Sbjct: 529  PKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGL 588

Query: 604  ----GLPGLPGDKGHRGERGPQGPPGPPGDDGMRG------------------EDGEIGP 641
                G+PGL G+KG+ GE GP G PGPPG  G  G                  +DG++  
Sbjct: 589  PGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRV 648

Query: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL 701
              LPG +G +G  GP G  G PG+ G AG  G  G KG+ G  G+PG PG  G PG  G 
Sbjct: 649  VALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGE 707

Query: 702  PGPQGPIGPPGEKGP---------------QGKPGLAGLPGADGPP--GHPGKEGQSGEK 744
            PG QGP GP GEKG                 G+PG  G  G  GP   G PGK GQ G  
Sbjct: 708  PGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLP 767

Query: 745  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
            G  GPPG +G  G PGP G          +G +G +GE G PG  G  GL G RG  G  
Sbjct: 768  GVQGPPGLKGVQGEPGPPG----------RGVQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817

Query: 805  GPRGEDGPEGPKGRAGPTGDPGP--SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862
            G +G  G  G KG  GP G PG   SG  G  G+ G  GL G PG +GP+G  G PG   
Sbjct: 818  GEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECS 877

Query: 863  --ANGEKGARGVAGKP----GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 916
              + G+    G+ G P    G   Q GP GP G  G  GP G PG +G  G +G PG PG
Sbjct: 878  CPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPG 937

Query: 917  ----------------------------------ERGPQGPQGPVGFPG----------- 931
                                              E+G +G QG  G PG           
Sbjct: 938  LTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSL 997

Query: 932  ------------PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG 979
                         +G PG  G  GLPG PG  G+   +G+ GPPG  G  GP GP G  G
Sbjct: 998  ERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQ---RGEEGPPGMRGSPGPPGPIGPPG 1054

Query: 980  PIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA-- 1037
              G  G PG PG  GE+GL G  G +G  G PG  G  G  GP GL G  GERG  G+  
Sbjct: 1055 FPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAG 1114

Query: 1038 -QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP------IGLPGRPGPQGPPGPAGEKG 1090
             +G PG  G EG  GPPGP G  GERG  G +G        G PG PGP GPPG  G+ G
Sbjct: 1115 EKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVG 1174

Query: 1091 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1150
            +PG  GPQ   G +G++GP GLPG  GP G PG  G  G  G  G+ G  G +G+ GP G
Sbjct: 1175 SPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAG 1234

Query: 1151 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1210
            PPGL GP G  G  G  G PGP+G  G  G  G  G  G  G PG +G QG PGPPG   
Sbjct: 1235 PPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGH-- 1292

Query: 1211 ENGDVGPMGPPGPPGP-----------RGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259
                VGP GPPG PGP           RG  G  G  G  G PG  G  G  GE G  G 
Sbjct: 1293 ----VGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGA 1348

Query: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFP---GD 1316
            AG  GPPG+ G  GP G +G+ G AG  G AG  G  G PG  G  G+ GPVG P   G+
Sbjct: 1349 AGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGE 1408

Query: 1317 PGPPGEPGPAGQDGVGGDKGEDGD------------------------------------ 1340
             G PG PGP+G  G+ G  G  GD                                    
Sbjct: 1409 RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEM 1468

Query: 1341 ---PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP--------P 1389
               PG+PGPPG  G  G PG PG  G PG  G EGRQG  G +G  G +G          
Sbjct: 1469 AAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIA 1528

Query: 1390 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441
            G+ G  GP GP G PG  G  G  GP+G+QG+PG     GPPGPMG PG  G
Sbjct: 1529 GENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPGI---PGPPGPMGQPGKAG 1576



 Score =  701 bits (1810), Expect = 0.0
 Identities = 522/1522 (34%), Positives = 647/1522 (42%), Gaps = 316/1522 (20%)

Query: 80   AQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNEHGIQQIGVEVGRSPV 136
            A ++ PT+++FP G  PE+F+++ T+  KK       +L  + + +G  QI +EV     
Sbjct: 82   APVTQPTRRVFPRG-LPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQER 140

Query: 137  FLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAISVEKKTVTMIVDCKKKTTKPLDRSERA 196
             L     G+       +F    + D +WH++ +SV  +  ++ VDC   +++PL    R 
Sbjct: 141  SLELRAQGQDGDFVSCIFPVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPL--GPRR 198

Query: 197  IVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAYD--YCEHYSPDCDSSAPKAAQ-A 253
             +   G    G      +    D+QQ  I  DP+   +   CE     C     KA +  
Sbjct: 199  PMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDT 258

Query: 254  QEPQIDEYAPED---IIEYDYEYGEAEYKEAESVTEG--PTVTEETIAQTEANIVDDFQE 308
            Q  ++ E  P+    +    +   E +  E ++   G      E      +    D+   
Sbjct: 259  QSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPP 318

Query: 309  YNYGTMESYQTEAPRHVSG----TNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKE 364
              +G  +S  T AP    G       P P      E+   G D      ++     E  +
Sbjct: 319  CVHGARDSNVTLAPSGPKGGKGERGLPGPPGS-KGEKGARGNDCVRISPDAPLQCAEGPK 377

Query: 365  IDGRDSDLL----VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHG 420
             +  +S  L    + G  GE    + ++ +      P +    G P E  +         
Sbjct: 378  GEKGESGALGPSGLPGSTGEKG-QKGEKGDGGIKGVPGKPGRDGRPGEICV--------- 427

Query: 421  AYGEKGQKGEPAVVEPGMLV--EGPPGPAGPAGIMGPPGLQG-PTGPPGDPGDRGPPGRP 477
              G KGQKG+P  V P  L    GPPG  GP GI G PG  G P GPPG  GD+G  G P
Sbjct: 428  -IGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIP 485

Query: 478  GLPGADGLPGPPG--------------------TMLMLPFRYGGDGSKGPTISAQE---- 513
            G  G  G PG PG                      + LP + G  G  G  + A+     
Sbjct: 486  GKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGI 545

Query: 514  ------------AQAQAILQQARIALRGPPGPM-----GLTGRPGPVGGPGSSGAKGESG 556
                        + +  +  Q  ++  G  G +     GL G PG  G PG  G KG  G
Sbjct: 546  QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFG 605

Query: 557  DPGPQGPRGVQGPPGPTGKPGKRGR---------------------PGADGGRGMPGEP- 594
            + GP G  G  GP GP G  G +G                      PG  G +G PG P 
Sbjct: 606  EAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPG 665

Query: 595  -GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP------------ 641
             G  G +G  G  GL G KG  G  G  G PG  G  G+ GE G  GP            
Sbjct: 666  FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCT 725

Query: 642  ------------RGLPGEAGPRGLLGPRGT--PGAPGQPGMAGVDGPPGPKGNMGPQGEP 687
                         G PG+ GP+G  GP G   PG PGQPG+ GV GPPG K   G QGEP
Sbjct: 726  ACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLK---GVQGEP 782

Query: 688  GPPGQ-----------QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP---- 732
            GPPG+            G PG QGLPGP+GP GP GEKG QG PG+ G  G  GPP    
Sbjct: 783  GPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASV 842

Query: 733  -GHPGKEGQSGEKGALG------------------------------------------P 749
             G PG++GQ G+ G  G                                           
Sbjct: 843  SGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQ 902

Query: 750  PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF------------------------ 785
            PGPQGP G PGP G  G  G++G+ G+ G  G+ G                         
Sbjct: 903  PGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQG 962

Query: 786  ----PGFKGDMGLKGDRGEVGQIG-------------PRGE----DGPEGPKGRAGPTGD 824
                PG+  + G KGD+G  G  G             PR E    D  EG  G  G  G 
Sbjct: 963  QRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGL 1022

Query: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF------PGFPGANGEKGARGVA---GK 875
            PGP G  G++G+ G PG+ G PG  GP G  GF      PG PG  GE+G  G+    G+
Sbjct: 1023 PGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGE 1082

Query: 876  PGPRGQ---RGPTGP---------RGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGP 923
            PGP GQ    G TGP         RG  G+ G  G+PGP G+ G  GPPGP G RG +GP
Sbjct: 1083 PGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGP 1142

Query: 924  ------------QGPVGFPGPKGPPGPPGKDGLPGHPGQ---------RGETGFQGKTGP 962
                        QG  GFPGP GPPG PGK G PG PG          RG +G  G  GP
Sbjct: 1143 QGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGP 1202

Query: 963  PGPGGVVGP---QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019
            PGP G+ GP    G  G+ G  G RG PGP GPPG  G PG  GK G  G PGP+G  GK
Sbjct: 1203 PGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGK 1262

Query: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP-----------GERGSAGTA 1068
             GP G  G PG  G PGA G  G  G  G  GPPGP G P           G+RG+ G  
Sbjct: 1263 PGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGER 1322

Query: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128
            G  GLPG+PGP G PGP GE G  G  G +GP G+ G  GP G  G  G AG  G+ G+K
Sbjct: 1323 GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEK 1382

Query: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG----------- 1177
            G  G PG  G  G  G  GPPGP G +G  GAPG +G  G PG  G  G           
Sbjct: 1383 GRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRF 1442

Query: 1178 -------MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQ 1230
                   MF ++          P       G PGPPG+ G  G  G  G PG PG  G +
Sbjct: 1443 IRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGRE 1502

Query: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAA 1290
            G  G  G +G PG+ G  G +G  G  GE G PGPPG  G  G     G+ G  GP G  
Sbjct: 1503 GRQGLPGVRGLPGTKGEKGDIG-IGIAGENGLPGPPGPQGPPG----YGKMGATGPMGQQ 1557

Query: 1291 GPPGAKGPPGDDGPKGNPGPVG 1312
            G PG  GPP   GP G PG  G
Sbjct: 1558 GIPGIPGPP---GPMGQPGKAG 1576



 Score =  684 bits (1766), Expect = 0.0
 Identities = 449/1112 (40%), Positives = 523/1112 (47%), Gaps = 170/1112 (15%)

Query: 386  YKEYEDKPTSP-PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEP-----AVVEPGML 439
            ++ +   P  P P  E G  VPA  D         G  G KG+KGEP     +VV    L
Sbjct: 517  FQNFVGLPGKPGPKGEPGDPVPARGD--------PGIQGIKGEKGEPCLSCSSVVGAQHL 568

Query: 440  VE--GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPF 497
            V   G  G  G  G  G PGL G  G PG  G++G  G  G  G+ G PGP G       
Sbjct: 569  VSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPA----- 622

Query: 498  RYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGD 557
              G  G+KG     +   A + LQ   + +   PGP G  G PGP G  G  G +G++G+
Sbjct: 623  --GIKGAKGEP--CEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGE 677

Query: 558  PGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDG------------- 604
             G +G +G  G PG  G PG  GRPG  G  G+ G  G KG++G DG             
Sbjct: 678  RGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKG-DGCTACPSLQGTVTD 736

Query: 605  LPGLPGDKGHRGERGPQGP--PGPPGDDGMRGEDGEIGPRGLPGEAGP--RGLLGPRGTP 660
            + G PG  G +GE+GP+G   PG PG  G+ G  G  G +G+ GE GP  RG+ GP+G P
Sbjct: 737  MAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEP 796

Query: 661  GAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720
            GAPG PG+ G+ GP GP G  G +G  G PG +G  GP G PG     GPPG  G QG+ 
Sbjct: 797  GAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVS-GPPGRDGQQGQT 855

Query: 721  GLAGLPGADGPPGHPGKEGQ-----------SGEKGALG-------PPGPQGPIGYPGPR 762
            GL G PG  GP G  G+ G+           SG  GA G        PGPQGP G PGP 
Sbjct: 856  GLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPP 915

Query: 763  GVKGADGVRGLKGSKGEKGEDGF----------------------------PGFKGDMGL 794
            G  G  G++G+ G+ G  G+ G                             PG+  + G 
Sbjct: 916  GPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGE 975

Query: 795  KGDRGEVGQIG-------------PRGE----DGPEGPKGRAGPTGDPGPSGQAGEKGKL 837
            KGD+G  G  G             PR E    D  EG  G  G  G PGP G  G++G+ 
Sbjct: 976  KGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEE 1035

Query: 838  GVPGLPGYPGRQGPKGSTGFPGF---PGANGEKGARGVAGKPGPRGQRGPTGPRGSRGAR 894
            G PG+ G PG  GP G  GFPG    PG  G +G RG+ G  G +G+ GP G  G  GA 
Sbjct: 1036 GPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 895  GPTGKPGPKG------TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGK------D 942
            GP G PG KG      ++G  G PGPPG  G  GP GP G  G +GP G  G+       
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQ 1155

Query: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002
            G PG PG  G  GF GK G PGP G    +G  G  GP G  G PGPPGPPG QG  G  
Sbjct: 1156 GQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLD 1215

Query: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062
            G +G  G PG +G  G  GP GL G PG +G  G  G PG KG  G  GPPG  G PG  
Sbjct: 1216 GLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAE 1275

Query: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKG-----APGEKGPQGPAGRDGVQGPVGLPGPAG 1117
            G  G  GP G PG PG  GPPGP G+ G     A G KG +G  G  G+ G  G PGP G
Sbjct: 1276 GEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPG 1335

Query: 1118 ---PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1174
               P G PG DG  G+ G PG++G  G  G  G PG  G +G  G  G AG  G PG  G
Sbjct: 1336 HPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSG 1395

Query: 1175 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVG------------------ 1216
              G  G  G  G RG PG PGP G  GLPG PG  G+  +                    
Sbjct: 1396 SMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERM 1455

Query: 1217 ---------PM---GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1264
                     PM     PG PGP G  G  G  G  G PG  G +G  G +G PG  G PG
Sbjct: 1456 AYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPG 1515

Query: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPG-----AKGPPGDDGPKGNPGPVGFPGDPGP 1319
              GE G  G  G  GE G  GPPG  GPPG     A GP G  G  G PGP G  G PG 
Sbjct: 1516 TKGEKGDIGI-GIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGK 1574

Query: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351
             G   P+  D  G    E   P      GP G
Sbjct: 1575 AGHCNPS--DCFGAMPMEQQYPPMKTMKGPFG 1604



 Score =  678 bits (1750), Expect = 0.0
 Identities = 454/1146 (39%), Positives = 517/1146 (45%), Gaps = 250/1146 (21%)

Query: 641  PRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQG 700
            P+    +A   G +  +   GA      A  + PP   G         P G +G  G +G
Sbjct: 284  PQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERG 343

Query: 701  LPGPQG-------------------PI----GPPGEKGPQGKPGLAGLPGADGPPGHPGK 737
            LPGP G                   P+    GP GEKG  G  G +GLPG+ G  G  G+
Sbjct: 344  LPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGE 403

Query: 738  EGQSGEKGALGPPGPQGPIG---YPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794
            +G  G KG  G PG  G  G     GP+G KG  G  G +G  GE G  G PG  G +GL
Sbjct: 404  KGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPG-IGL 462

Query: 795  KGDRGEV-GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKG---------KLGVPGLPG 844
             G  G+  G  GP+G+ G  G  G+ GP G PG  G  GEKG           G     G
Sbjct: 463  PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVG 522

Query: 845  YPGRQGPKGSTGFP----GFPGANGEKGARG--------VAGKPGPRGQRGPTGPRGS-- 890
             PG+ GPKG  G P    G PG  G KG +G        V G        G +G  GS  
Sbjct: 523  LPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG 582

Query: 891  ---RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVG------------------- 928
                G  G  G PG KG  G  G  GP G  GP GP GP G                   
Sbjct: 583  FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQ 642

Query: 929  --------FPGP---KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGE 977
                     PGP   KG PGPPG  GLPG  G+ GE G +G+ G  G  G  G  G TG 
Sbjct: 643  DGDVRVVALPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701

Query: 978  TGPIGERGHPGPPGPPGEQG-----LPGAAG----KEGAKGDPGPQGISGKDGPAGLRGF 1028
             G  GE G  GP GP GE+G      P   G      G  G PGP+G  G +G  G  G 
Sbjct: 702  PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG-VGRPGK 760

Query: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1088
            PG+ GLPG QG PGLKG +G  GPPG  G  G +G  G  G  G+ G PGP+GPPGP GE
Sbjct: 761  PGQPGLPGVQGPPGLKGVQGEPGPPGR-GVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGE 819

Query: 1089 KGA---PGEKGPQGPAGRDG--VQGPVGLPGPAGPA---GSPGEDGDKGEIGEPGQ---- 1136
            KGA   PG KG  GP G  G  V GP G  G  G     G+PGE G +GE GEPG+    
Sbjct: 820  KGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP 879

Query: 1137 -----------------KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMF 1179
                              GS    G  GPPG PG  GP G PG+ G  G  G  GQ G+ 
Sbjct: 880  SQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLT 939

Query: 1180 ----------------------------------GQKGDEGARGFP-------------- 1191
                                              G+KGD+G  G P              
Sbjct: 940  AELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLER 999

Query: 1192 ------------GPPGPIGLQGLPGPPGEKGENGDVGP---MGPPGPPGPRGPQGPNGAD 1236
                        G PG +G  GLPGPPG  G+ G+ GP    G PGPPGP GP G  GA 
Sbjct: 1000 PRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAV 1059

Query: 1237 GPQGPPGSVGS---VGGVGEKGEPGEAGNPGPPGEA---GVGGPKGER------GEKGEA 1284
            G  G PG  G     G  G+KGEPG  G PG PG     G+ G KGER      GEKGE 
Sbjct: 1060 GSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP 1119

Query: 1285 GPPGA---AGPPGAKGPPGDDGPKGN---------PGPVGFPGDPGPPGEPGPAGQDGVG 1332
            GPPG+    GPPG  GP G+ GP+GN          G  GFPG PGPPG PG  G  G  
Sbjct: 1120 GPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179

Query: 1333 GDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1392
            G + E G  G  GP G  G  GPPGPPG +GP G  G +G+ G+ G +G+ G  GPPG  
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLM 1239

Query: 1393 GP------------VGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440
            GP             GP+G  GKPGP G  G PG  GE G  G  G+ GPPG +GPPG P
Sbjct: 1240 GPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPP 1299

Query: 1441 -----------GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG 1489
                       GLKGD G+ GE+G  GL G  GPPG  G  G+ G  G  G  G  G  G
Sbjct: 1300 GQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359

Query: 1490 IPGPAGPLGPPGP---------------PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG 1534
              GP GP G PG                PG PG  G  G  G  GPAG++G  G PGP G
Sbjct: 1360 FYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSG 1419

Query: 1535 SPGPPG 1540
            SPG PG
Sbjct: 1420 SPGLPG 1425



 Score =  265 bits (678), Expect = 2e-70
 Identities = 169/415 (40%), Positives = 200/415 (48%), Gaps = 65/415 (15%)

Query: 1192 GPPGPIGLQGLPGPPGEKGENG----DVGPMGPPGP----PGPRGPQGPNGADGPQGPPG 1243
            GP G  G +GLPGPPG KGE G    D   + P  P     GP+G +G +GA GP G PG
Sbjct: 334  GPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPG 393

Query: 1244 SVGSVGGVGEKGE------PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297
            S G  G  GEKG+      PG+ G  G PGE  V GPKG++G+ G  GP G AG PG  G
Sbjct: 394  STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG 453

Query: 1298 PPGDDG---------PKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDP------- 1341
             PG  G         P G PGP G  G  G PG+ GP G+ G  G KGE GDP       
Sbjct: 454  LPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTL 513

Query: 1342 --------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK--------GAKGEAGA 1385
                    G PG PGP GE G P P   RG PG  G +G +GE         GA+    +
Sbjct: 514  PEGFQNFVGLPGKPGPKGEPGDPVPA--RGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSS 571

Query: 1386 EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGD 1445
             G  G  G  G  G  G PG  G+ G+ G  G  G  G AG  GPPGP+GP G+ G KG+
Sbjct: 572  TGASGDVGSPG-FGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGE 630

Query: 1446 PG------SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGP 1499
            P       S  + G   ++ L GP GE+GE G  G  G  G  G  G+ G+ G  G  G 
Sbjct: 631  PCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGN 689

Query: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKT 1554
            PG PG PG         +TG  G  G+ G+ GP G  G  G+     P L    T
Sbjct: 690  PGDPGTPG---------TTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVT 735



 Score =  225 bits (574), Expect = 3e-58
 Identities = 158/368 (42%), Positives = 179/368 (48%), Gaps = 43/368 (11%)

Query: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288
            P GP G  G +G PG  GS G  G +G      +P  P +   G PKGE+GE G  GP G
Sbjct: 332  PSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG-PKGEKGESGALGPSG 390

Query: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348
                PG+ G  G  G KG+ G  G PG PG  G PG   +  V G KG+ GDPG  GP G
Sbjct: 391  L---PGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPG---EICVIGPKGQKGDPGFVGPEG 444

Query: 1349 PSGEAGPPGPPGKRGP--PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGP 1406
             +GE GPPG PG  G   PG  G  G  G  G KG+ G+ G PGK GP    G  GKPG 
Sbjct: 445  LAGEPGPPGLPGPPGIGLPGTPGDPG--GPPGPKGDKGSSGIPGKEGP---GGKPGKPGV 499

Query: 1407 EGLRGIPG---PVGEQGLPGAAGQDGPPGPMGPPGLP-GLKGDPGS---KGEKGHP---- 1455
            +G +G P    P   +G     G  G PGP G PG P   +GDPG    KGEKG P    
Sbjct: 500  KGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSC 559

Query: 1456 ----GLIGLIGPPGEQGEKGDRG-----LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1506
                G   L+   G  G+ G  G     LPG  G PG KG+ G  G AGP G PGPPG  
Sbjct: 560  SSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPV 619

Query: 1507 GPQGPKGNKGSTG---PAG---QKGDS---GLPGPPGSPGPPGEVIQPLPILSSKKTRRH 1557
            GP G KG KG      PA    Q GD     LPGP G  G PG     LP    K   R 
Sbjct: 620  GPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERG 679

Query: 1558 TEGMQADA 1565
             +G + DA
Sbjct: 680  LKGQKGDA 687



 Score =  211 bits (536), Expect = 7e-54
 Identities = 146/360 (40%), Positives = 167/360 (46%), Gaps = 49/360 (13%)

Query: 1238 PQGPPGSVGSVGGVGEKGEPGE------AGNPGPPGEAGV---------GGPKGERGEKG 1282
            PQ         G + +K E G       A +  PP   G           GPKG +GE+G
Sbjct: 284  PQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERG 343

Query: 1283 EAGPPGAAGPPGAKG-------PPGD----DGPKGNPGPVGFPGDPGPPGEPGPAGQDGV 1331
              GPPG+ G  GA+G       P       +GPKG  G  G  G  G PG  G  GQ G 
Sbjct: 344  LPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGE 403

Query: 1332 GGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP--P 1389
             GD G  G PG+PG  G  GE    GP G++G PG  G EG  GE G  G  G  G   P
Sbjct: 404  KGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLP 463

Query: 1390 GKTG-PVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG------PMGPPGLPGL 1442
            G  G P GP GP G  G  G+ G  GP G+ G PG  G+ G P       P G     GL
Sbjct: 464  GTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGL 523

Query: 1443 KGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--------GTQ---GSPGAKGDGGIP 1491
             G PG KGE G P  +   G PG QG KG++G P        G Q    S GA GD G P
Sbjct: 524  PGKPGPKGEPGDP--VPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSP 581

Query: 1492 GPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSS 1551
            G   P G PG  G+PG +G KGN G  GPAG  G  G  GP G  G  GE  +P P LS+
Sbjct: 582  GFGLP-GLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSN 640


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.142    0.449 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 131,183,050
Number of Sequences: 37866
Number of extensions: 11862551
Number of successful extensions: 382219
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 707
Number of HSP's successfully gapped in prelim test: 2012
Number of HSP's that attempted gapping in prelim test: 33942
Number of HSP's gapped (non-prelim): 58949
length of query: 1806
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1689
effective length of database: 13,817,196
effective search space: 23337244044
effective search space used: 23337244044
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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