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Search of human proteins with 89142745
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|89142745 tumor necrosis factor receptor superfamily, member
25 isoform 12 precursor [Homo sapiens]
(181 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 409 e-115
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 409 e-115
gi|89142745 tumor necrosis factor receptor superfamily, member 2... 409 e-115
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 409 e-115
gi|23200025 tumor necrosis factor receptor superfamily, member 2... 282 1e-76
gi|23200031 tumor necrosis factor receptor superfamily, member 2... 116 1e-26
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 77 1e-14
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 67 8e-12
gi|23510423 tumor necrosis factor receptor superfamily, member 6... 65 2e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6... 65 2e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 65 2e-11
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 59 3e-09
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 54 1e-07
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 54 1e-07
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 49 2e-06
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 48 5e-06
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 48 5e-06
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 47 9e-06
gi|148743793 osteoprotegerin precursor [Homo sapiens] 45 3e-05
gi|23238204 tumor necrosis factor receptor superfamily, member 1... 45 3e-05
gi|23238202 tumor necrosis factor receptor superfamily, member 1... 45 3e-05
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 42 4e-04
gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens] 41 6e-04
gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo sapi... 41 6e-04
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 40 8e-04
gi|21264602 laminin alpha 5 [Homo sapiens] 40 0.001
gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo... 40 0.001
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 39 0.002
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 39 0.003
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 39 0.003
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 409 bits (1051), Expect = e-115
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
Query: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
Query: 181 T 181
T
Sbjct: 181 T 181
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 409 bits (1051), Expect = e-115
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
Query: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
Query: 181 T 181
T
Sbjct: 181 T 181
>gi|89142745 tumor necrosis factor receptor superfamily, member 25
isoform 12 precursor [Homo sapiens]
Length = 181
Score = 409 bits (1051), Expect = e-115
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
Query: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
Query: 181 T 181
T
Sbjct: 181 T 181
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 409 bits (1051), Expect = e-115
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
Query: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
Query: 181 T 181
T
Sbjct: 181 T 181
>gi|23200025 tumor necrosis factor receptor superfamily, member 25
isoform 4 precursor [Homo sapiens]
Length = 372
Score = 282 bits (721), Expect = 1e-76
Identities = 136/181 (75%), Positives = 136/181 (75%), Gaps = 45/181 (24%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53
Query: 61 CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
ASQVALENCSAVADTRCGCKPG
Sbjct: 54 --------------------------------------ASQVALENCSAVADTRCGCKPG 75
Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 76 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135
Query: 181 T 181
T
Sbjct: 136 T 136
>gi|23200031 tumor necrosis factor receptor superfamily, member 25
isoform 7 precursor [Homo sapiens]
Length = 234
Score = 116 bits (290), Expect = 1e-26
Identities = 53/53 (100%), Positives = 53/53 (100%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53
MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA
Sbjct: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 76.6 bits (187), Expect = 1e-14
Identities = 46/151 (30%), Positives = 61/151 (40%), Gaps = 8/151 (5%)
Query: 29 RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
R C H + CC C G YL C P ++ C C +F A ENH
Sbjct: 40 RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98
Query: 89 CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
C C C ++ QV + +C+ DT CGC+ Q S + F C C C L+
Sbjct: 99 CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151
Query: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSC 179
L C + TC GF+ + CVSC
Sbjct: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSC 182
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 67.0 bits (162), Expect = 8e-12
Identities = 48/168 (28%), Positives = 64/168 (38%), Gaps = 16/168 (9%)
Query: 15 LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74
L L LGA +P + +G CC C G+ +K C E G + C CP
Sbjct: 25 LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79
Query: 75 QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134
T++A N S+C +CQ CD A NCS + CGC PG F C+
Sbjct: 80 PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131
Query: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSC 179
+C C R+ +DT C C PG + C
Sbjct: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEEC 179
>gi|23510423 tumor necrosis factor receptor superfamily, member 6
isoform 3 precursor [Homo sapiens]
Length = 220
Score = 65.5 bits (158), Expect = 2e-11
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 44 GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
G FC + CP G CT C+ C + + H +S+C RC+ CDE
Sbjct: 56 GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
NC+ +T+C CKP +F C S+ +C PC C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
>gi|23510421 tumor necrosis factor receptor superfamily, member 6
isoform 2 precursor [Homo sapiens]
Length = 314
Score = 65.5 bits (158), Expect = 2e-11
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 44 GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
G FC + CP G CT C+ C + + H +S+C RC+ CDE
Sbjct: 56 GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
NC+ +T+C CKP +F C S+ +C PC C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
>gi|4507583 tumor necrosis factor receptor superfamily, member 6
isoform 1 precursor [Homo sapiens]
Length = 335
Score = 65.5 bits (158), Expect = 2e-11
Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)
Query: 44 GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
G FC + CP G CT C+ C + + H +S+C RC+ CDE
Sbjct: 56 GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115
Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
NC+ +T+C CKP +F C S+ +C PC C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 58.5 bits (140), Expect = 3e-09
Identities = 51/173 (29%), Positives = 74/173 (42%), Gaps = 17/173 (9%)
Query: 1 MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
M R R + A LLL L AR Q + C + H + CC C G Y+ +
Sbjct: 1 MAPRARRRRPLFALLLLCALLARLQVALQIAP-PCTSEKHYEHLGRCCNKCEPGKYMSSK 59
Query: 61 CTEPCGNSTCLVCPQDTFL-AWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKP 119
CT +S CL C D +L +W + +C + CD + VA+ ++ RC C
Sbjct: 60 CT-TTSDSVCLPCGPDEYLDSW--NEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTA 116
Query: 120 G--WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY 170
G W +C+ + + C P L GA H L +DT C CL G++
Sbjct: 117 GYHWSQDCECCRRNTE----CAPGL--GAQHP----LQLNKDTVCKPCLAGYF 159
>gi|4507587 tumor necrosis factor receptor superfamily, member 7
precursor [Homo sapiens]
Length = 260
Score = 53.5 bits (127), Expect = 1e-07
Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)
Query: 44 GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
G CC+ C G +L C + + C C + ++H C C+ C+ S +
Sbjct: 36 GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92
Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135
+ NC+ A+ C C+ GW +C+ +C P
Sbjct: 93 VRNCTITANAECACRNGW--QCRDKECTECDP 122
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 53.5 bits (127), Expect = 1e-07
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)
Query: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
CC CP G Y+ A C+ ++ C C ++++ H N + C C+ CD +
Sbjct: 58 CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113
Query: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
C++ T+C C+PG F +C +C+ DC
Sbjct: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 48.9 bits (115), Expect = 2e-06
Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)
Query: 38 DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
+++ + CC C G + K CT+ ++ C C T+ N C +C
Sbjct: 44 EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98
Query: 98 QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
+ S QV + C+ + C C+PGW+ C +S+ C P C R
Sbjct: 99 RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154
Query: 156 SRRDTDCGTCLPGFYEH 172
D C C PG + +
Sbjct: 155 ETSDVVCKPCAPGTFSN 171
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 47.8 bits (112), Expect = 5e-06
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 15/129 (11%)
Query: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
CC C G L + CTE + CL C + FL N + C + + CD +
Sbjct: 37 CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94
Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
++ DT C C+ GW C S + C+ C+ C ++ DT C
Sbjct: 95 GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144
Query: 164 TCLPGFYEH 172
C GF+ +
Sbjct: 145 PCPVGFFSN 153
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 47.8 bits (112), Expect = 5e-06
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 15/129 (11%)
Query: 47 CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
CC C G L + CTE + CL C + FL N + C + + CD +
Sbjct: 37 CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94
Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
++ DT C C+ GW C S + C+ C+ C ++ DT C
Sbjct: 95 GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144
Query: 164 TCLPGFYEH 172
C GF+ +
Sbjct: 145 PCPVGFFSN 153
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 47.0 bits (110), Expect = 9e-06
Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
C CPAG Y+ CT C CP TF H + +C C + +E
Sbjct: 67 CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121
Query: 107 -CSAVADTRCGCKPGWF 122
C+A+ D C C PG F
Sbjct: 122 PCAALTDRECTCPPGMF 138
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 45.4 bits (106), Expect = 3e-05
Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106
C CP G YLK CT + C CP D + H + EC C C E Q +
Sbjct: 41 CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96
Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166
C+ + C CK G ++E + +C C + R+T C C
Sbjct: 97 CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146
Query: 167 PGFYEH 172
GF+ +
Sbjct: 147 DGFFSN 152
>gi|23238204 tumor necrosis factor receptor superfamily, member 19
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 45.1 bits (105), Expect = 3e-05
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 86 NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
+ +C + + D + V C + C G+ V C++ + F C+
Sbjct: 31 SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170
PCLDC ++R + CS D CG CLPGFY
Sbjct: 91 PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
>gi|23238202 tumor necrosis factor receptor superfamily, member 19
isoform 1 precursor [Homo sapiens]
Length = 423
Score = 45.1 bits (105), Expect = 3e-05
Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)
Query: 86 NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
+ +C + + D + V C + C G+ V C++ + F C+
Sbjct: 31 SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170
PCLDC ++R + CS D CG CLPGFY
Sbjct: 91 PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 41.6 bits (96), Expect = 4e-04
Identities = 53/182 (29%), Positives = 65/182 (35%), Gaps = 53/182 (29%)
Query: 26 GGTRSP---RCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPC------------GNSTC 70
GGT SP C C + GL C CP+G + C E C G+ +C
Sbjct: 455 GGTCSPVDGSCTCKEGWQ---GLDCTLPCPSGTW-GLNCNESCTCANGAACSPIDGSCSC 510
Query: 71 ----------LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVAD---TRCG- 116
L CP TF + H +C+ CD +C +A RC
Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEH-CDCSHADGCDPVTG-----HCCCLAGWTGIRCDS 564
Query: 117 -CKPG-WFVECQVSQCVSSSPFYCQP---CLDCGALHRHTRLLCSRRDTDCGTCLPGFYE 171
C PG W C VS C + C P +C R LC R C PGFY
Sbjct: 565 TCPPGRWGPNCSVS-CSCENGGSCSPEDGSCECAPGFRGP--LCQR------ICPPGFYG 615
Query: 172 HG 173
HG
Sbjct: 616 HG 617
Score = 41.2 bits (95), Expect = 5e-04
Identities = 46/168 (27%), Positives = 60/168 (35%), Gaps = 44/168 (26%)
Query: 26 GGTRSPR---CDCAGDFHKKIGLFCCRGCPAGHY-------------LKAPCTEPCGNST 69
GG+ SP C+CA F G C R CP G Y PC G
Sbjct: 584 GGSCSPEDGSCECAPGFR---GPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE 640
Query: 70 CL------VCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFV 123
CL +C Q + + +CA+ +C + CS + D C C PGW
Sbjct: 641 CLPGFSGALCNQ---VCAGGYFGQDCAQLCSCANNGT------CSPI-DGSCQCFPGWIG 690
Query: 124 ECQVSQCVSSSP--FYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGF 169
+ C + P F+ C A H CS D C C PG+
Sbjct: 691 K----DCSQACPPGFWGPACFH--ACSCHNGASCSAEDGAC-HCTPGW 731
Score = 33.9 bits (76), Expect = 0.078
Identities = 47/177 (26%), Positives = 56/177 (31%), Gaps = 49/177 (27%)
Query: 33 CDCAGDFHKKIGLFCCRGCPAGHYLK-----------APCTEPCGNSTC----------L 71
C CA F +G C C AG Y C+ G+ TC L
Sbjct: 422 CTCAPGF---MGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTL 478
Query: 72 VCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCV 131
CP T W + N C C A+ CS + D C C PGW + C
Sbjct: 479 PCPSGT---WGLNCNESCT----CANGAA------CSPI-DGSCSCTPGWLGDTCELPCP 524
Query: 132 S-------SSPFYCQPCLDCGALHRHTRLLCSRRDTDC-GTCLPGFYEHGDGC-VSC 179
S C C + H L C TC PG + G C VSC
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW--GPNCSVSC 579
Score = 29.3 bits (64), Expect = 1.9
Identities = 43/167 (25%), Positives = 59/167 (35%), Gaps = 40/167 (23%)
Query: 24 AQGGTRSP---RCDCAGDFHKKIGLFCCRGCPAGH-----------YLKAPCTEPCGNST 69
A GT SP C C F IG C + CP G + A C+ G
Sbjct: 670 ANNGTCSPIDGSCQC---FPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726
Query: 70 C------LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFV 123
C L C Q A+ +C R C AS C ++ +C C+ G+
Sbjct: 727 CTPGWTGLFCTQRCPAAF---FGKDCGRVCQCQNGAS------CDHISG-KCTCRTGFTG 776
Query: 124 ECQVSQCVSSSPFY-CQPCLDCGALHRHTRLLCSRRDTDCGTCLPGF 169
+ +C + Y CQ +C ++ T C C C PGF
Sbjct: 777 QHCEQRCAPGTFGYGCQQLCEC--MNNST---CDHVTGTC-YCSPGF 817
Score = 26.9 bits (58), Expect = 9.6
Identities = 13/32 (40%), Positives = 16/32 (50%), Gaps = 4/32 (12%)
Query: 146 ALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCV 177
A R R + RR C PG+YE GD C+
Sbjct: 73 AYRRGLRTMYRRRSQ----CCPGYYESGDFCI 100
>gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens]
Length = 789
Score = 40.8 bits (94), Expect = 6e-04
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENC 107
C C G + P G+ C VCP++T+ EC RC+ D Q S+ C
Sbjct: 50 CFPCKPGTFSNKP-----GSFNCQVCPRNTY---SEKGAKECIRCKD-DSQFSEEGSSEC 100
Query: 108 SAVADTRCGCKPGWFVECQVSQCVSSSPFY--CQPCLDCGALHRHTRLLCSRRDTDCGTC 165
+ C K + + + + Y +P + L RL S DC C
Sbjct: 101 TERPP--CTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPC 158
Query: 166 LPGFYEHG-DGCVSCP 180
PGFY +G C CP
Sbjct: 159 NPGFYNNGSSSCHPCP 174
Score = 30.8 bits (68), Expect = 0.66
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 7/46 (15%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE-CARC 92
C CP GHY++ + C CP DT+L+ + E C C
Sbjct: 378 CVPCPPGHYIEKETNQ------CKECPPDTYLSIHQVYGKEACIPC 417
Score = 27.3 bits (59), Expect = 7.3
Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 22/87 (25%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALE-- 105
C C G Y G+S+C CP TF + EC C A E A +
Sbjct: 155 CPPCNPGFYNN-------GSSSCHPCPPGTF----SDGTKECRPCPAGTEPALGFEYKWW 203
Query: 106 ---------NCSAVADTRCGCKPGWFV 123
+C V +++C GW V
Sbjct: 204 NVLPGNMKTSCFNVGNSKCDGMNGWEV 230
>gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo
sapiens]
Length = 1029
Score = 40.8 bits (94), Expect = 6e-04
Identities = 37/136 (27%), Positives = 52/136 (38%), Gaps = 14/136 (10%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENC 107
C C G + P G+ C VCP++T+ EC RC+ D Q S+ C
Sbjct: 290 CFPCKPGTFSNKP-----GSFNCQVCPRNTY---SEKGAKECIRCKD-DSQFSEEGSSEC 340
Query: 108 SAVADTRCGCKPGWFVECQVSQCVSSSPFY--CQPCLDCGALHRHTRLLCSRRDTDCGTC 165
+ C K + + + + Y +P + L RL S DC C
Sbjct: 341 TERPP--CTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPC 398
Query: 166 LPGFYEHG-DGCVSCP 180
PGFY +G C CP
Sbjct: 399 NPGFYNNGSSSCHPCP 414
Score = 30.8 bits (68), Expect = 0.66
Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 7/46 (15%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE-CARC 92
C CP GHY++ + C CP DT+L+ + E C C
Sbjct: 618 CVPCPPGHYIEKETNQ------CKECPPDTYLSIHQVYGKEACIPC 657
Score = 27.3 bits (59), Expect = 7.3
Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 22/87 (25%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALE-- 105
C C G Y G+S+C CP TF + EC C A E A +
Sbjct: 395 CPPCNPGFYNN-------GSSSCHPCPPGTF----SDGTKECRPCPAGTEPALGFEYKWW 443
Query: 106 ---------NCSAVADTRCGCKPGWFV 123
+C V +++C GW V
Sbjct: 444 NVLPGNMKTSCFNVGNSKCDGMNGWEV 470
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 40.4 bits (93), Expect = 8e-04
Identities = 42/177 (23%), Positives = 58/177 (32%), Gaps = 37/177 (20%)
Query: 15 LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74
LLL+LLG G + C + G CC+ C G + PC + C C
Sbjct: 16 LLLLLLGVSLGGAKEA----CPTGLYTHSGE-CCKACNLGEGVAQPC--GANQTVCEPCL 68
Query: 75 QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVE--------CQ 126
+ C C C S A C D C C G++ + C+
Sbjct: 69 DSVTFSDVVSATEPCKPCTECVGLQSMSA--PCVEADDAVCRCAYGYYQDETTGRCEACR 126
Query: 127 VSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY----EHGDGCVSC 179
V + S F CQ +++T C C G Y H D C+ C
Sbjct: 127 VCEAGSGLVFSCQ----------------DKQNTVCEECPDGTYSDEANHVDPCLPC 167
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 40.0 bits (92), Expect = 0.001
Identities = 54/215 (25%), Positives = 79/215 (36%), Gaps = 49/215 (22%)
Query: 5 PRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKI-GLFCCRGCPAGHYLKAPCTE 63
P G A+A+ + L L A +G + +CA F++ + GLF R P + +
Sbjct: 1818 PAGQGALASNVELCLCPASYRGDSCQ---ECAPGFYRDVKGLFLGRCVPCQCHGHSDRCL 1874
Query: 64 PCGNSTCLVCPQDT-----------FLAWENHHNSECARCQACDEQASQVALENCSAVAD 112
P G+ C+ C +T F++ + ++ C C S E C
Sbjct: 1875 P-GSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGG 1933
Query: 113 -TRCGCKPGWFVECQVSQCVSSSPFY----------CQPC------------LDCGALHR 149
T+C CKPG+ + C +P + CQPC DC L
Sbjct: 1934 RTQCLCKPGY----AGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTG 1989
Query: 150 HTRLLCSRRDTD--CGTCLPGFYEHG---DGCVSC 179
R C R T C C PGFY + C C
Sbjct: 1990 ACRG-CLRHTTGPRCEICAPGFYGNALLPGNCTRC 2023
Score = 37.7 bits (86), Expect = 0.005
Identities = 50/172 (29%), Positives = 62/172 (36%), Gaps = 41/172 (23%)
Query: 23 RAQGGTRSPRCD-CA-GDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLA 80
R + G CD CA G FH + C GC L C E CL P+
Sbjct: 561 RCRVGFEGATCDRCAPGYFHFPLCQLC--GCSPAGTLPEGCDEA---GRCLCQPE----- 610
Query: 81 WENHHNSECA-------RCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSS 133
+ H C CQAC + C A C C+PG+ + C
Sbjct: 611 FAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGG--LCRCRPGY----TGTACQEC 664
Query: 134 SPFY-----CQPCLDC---GALH-----RHTRLLCSRRDTD--CGTCLPGFY 170
SP + C PC C G+LH R + C R T C TC+PG Y
Sbjct: 665 SPGFHGFPSCVPC-HCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAY 715
Score = 28.5 bits (62), Expect = 3.3
Identities = 29/106 (27%), Positives = 38/106 (35%), Gaps = 21/106 (19%)
Query: 65 CGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVE 124
CG + CP W+ + CQ+C NC A T C P
Sbjct: 329 CGGTCDRCCPGFNQQPWKPATANSANECQSC----------NCYGHA-TDCYYDPE-VDR 376
Query: 125 CQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY 170
+ SQ + + C+DC H T + C R CLPGFY
Sbjct: 377 RRASQSLDGTYQGGGVCIDCQ--HHTTGVNCER-------CLPGFY 413
Score = 28.1 bits (61), Expect = 4.3
Identities = 30/96 (31%), Positives = 35/96 (36%), Gaps = 18/96 (18%)
Query: 91 RCQACDEQASQVALENC----SAVADTRCGCKP-GWFVECQVSQCVSSSPFYCQPCLDCG 145
RC C E + +C S+ DTR P G V C S + C
Sbjct: 457 RCDVCAEGFT--GFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNA-------CR 507
Query: 146 ALHRHTRLLCSR--RDTDCGTCLPGFYEHGDGCVSC 179
R R LC + T C C PGFY G GC C
Sbjct: 508 KDPRVGRCLCKPNFQGTHCELCAPGFY--GPGCQPC 541
>gi|145309304 cadherin EGF LAG seven-pass G-type receptor 3 [Homo
sapiens]
Length = 3312
Score = 39.7 bits (91), Expect = 0.001
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 20/85 (23%)
Query: 110 VADTRCGCKPGW---FVECQVSQCVSSSPFYCQPCLDCGALHRHT---RLLCSRR----- 158
+A RC C PG+ F E ++ C Y PC + GA R +C R
Sbjct: 1416 IAGLRCRCPPGFTGDFCETELDLC------YSNPCRNGGACARREGGYTCVCRPRFTGED 1469
Query: 159 ---DTDCGTCLPGFYEHGDGCVSCP 180
DT+ G C+PG +G C P
Sbjct: 1470 CELDTEAGRCVPGVCRNGGTCTDAP 1494
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 39.3 bits (90), Expect = 0.002
Identities = 40/152 (26%), Positives = 59/152 (38%), Gaps = 24/152 (15%)
Query: 13 AALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLV 72
AALLL+ LG G C GD + CC C G+ + + C+ N+ C
Sbjct: 14 AALLLLGLGLSTVTGLH-----CVGDTYPSNDR-CCHECRPGNGMVSRCSRS-QNTVCRP 66
Query: 73 CPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGC----------KPGWF 122
C + + + C C C+ ++ + C+A DT C C KPG
Sbjct: 67 CGPGFYN--DVVSSKPCKPCTWCNLRSGSERKQLCTATQDTVCRCRAGTQPLDSYKPG-- 122
Query: 123 VECQVSQCVSSSP---FYCQPCLDCGALHRHT 151
V+C SP C+P +C +HT
Sbjct: 123 VDCAPCPPGHFSPGDNQACKPWTNCTLAGKHT 154
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 38.5 bits (88), Expect = 0.003
Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 38/152 (25%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQA-CDEQASQVALEN 106
C CP G +++ PC +TC CP + + N + C C C E+ +
Sbjct: 49 CAQCPPGTFVQRPCRRD-SPTTCGPCPPRHYTQFWN-YLERCRYCNVLCGEREEEA--RA 104
Query: 107 CSAVADTRCGCKPGWFVEC----------------------QVSQC----------VSSS 134
C A + C C+ G+F Q +QC SSS
Sbjct: 105 CHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSS 164
Query: 135 PFYCQPCLDCGALHRHTRLL-CSRRDTDCGTC 165
CQP +C AL + S DT C +C
Sbjct: 165 SEQCQPHRNCTALGLALNVPGSSSHDTLCTSC 196
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 38.5 bits (88), Expect = 0.003
Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 38/152 (25%)
Query: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQA-CDEQASQVALEN 106
C CP G +++ PC +TC CP + + N + C C C E+ +
Sbjct: 49 CAQCPPGTFVQRPCRRD-SPTTCGPCPPRHYTQFWN-YLERCRYCNVLCGEREEEA--RA 104
Query: 107 CSAVADTRCGCKPGWFVEC----------------------QVSQC----------VSSS 134
C A + C C+ G+F Q +QC SSS
Sbjct: 105 CHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSS 164
Query: 135 PFYCQPCLDCGALHRHTRLL-CSRRDTDCGTC 165
CQP +C AL + S DT C +C
Sbjct: 165 SEQCQPHRNCTALGLALNVPGSSSHDTLCTSC 196
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.505
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,034,622
Number of Sequences: 37866
Number of extensions: 456786
Number of successful extensions: 2254
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 40
Number of HSP's successfully gapped in prelim test: 204
Number of HSP's that attempted gapping in prelim test: 1910
Number of HSP's gapped (non-prelim): 523
length of query: 181
length of database: 18,247,518
effective HSP length: 96
effective length of query: 85
effective length of database: 14,612,382
effective search space: 1242052470
effective search space used: 1242052470
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.