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Search of human proteins with 7657039
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657039 tumor necrosis factor receptor superfamily, member
21 precursor [Homo sapiens]
(655 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7657039 tumor necrosis factor receptor superfamily, member 21... 1335 0.0
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 120 4e-27
gi|14790170 tumor necrosis factor receptor superfamily, member 6... 115 2e-25
gi|148743793 osteoprotegerin precursor [Homo sapiens] 115 2e-25
gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 115 2e-25
gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 87 6e-17
gi|4505039 lymphotoxin beta receptor [Homo sapiens] 86 1e-16
gi|23200041 tumor necrosis factor receptor superfamily, member 1... 77 4e-14
gi|4507565 tumor necrosis factor receptor superfamily, member 11... 77 5e-14
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 76 9e-14
gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 64 6e-10
gi|68348711 tumor necrosis factor receptor superfamily, member 8... 62 1e-09
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 54 3e-07
gi|22547121 tumor necrosis factor receptor superfamily, member 1... 54 5e-07
gi|4759246 tumor necrosis factor receptor superfamily, member 18... 50 5e-06
gi|23238197 tumor necrosis factor receptor superfamily, member 1... 50 5e-06
gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 50 7e-06
gi|134031945 SCO-spondin [Homo sapiens] 50 9e-06
gi|23200023 tumor necrosis factor receptor superfamily, member 2... 47 6e-05
gi|23200021 tumor necrosis factor receptor superfamily, member 2... 47 6e-05
gi|89142745 tumor necrosis factor receptor superfamily, member 2... 47 6e-05
gi|4507569 tumor necrosis factor receptor superfamily, member 25... 47 6e-05
gi|224494026 tumor necrosis factor receptor superfamily, member ... 46 9e-05
gi|224494019 tumor necrosis factor receptor superfamily, member ... 46 9e-05
gi|21361086 tumor necrosis factor receptor superfamily, member 1... 46 9e-05
gi|22547108 tumor necrosis factor receptor superfamily, member 1... 44 4e-04
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 42 0.002
gi|23238194 tumor necrosis factor receptor superfamily, member 1... 41 0.003
gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens] 37 0.075
gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo sap... 36 0.098
>gi|7657039 tumor necrosis factor receptor superfamily, member 21
precursor [Homo sapiens]
Length = 655
Score = 1335 bits (3456), Expect = 0.0
Identities = 655/655 (100%), Positives = 655/655 (100%)
Query: 1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA 60
MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA
Sbjct: 1 MGTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA 60
Query: 61 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK 120
TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK
Sbjct: 61 TGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEK 120
Query: 121 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP 180
LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP
Sbjct: 121 LPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP 180
Query: 181 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE 240
SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE
Sbjct: 181 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHE 240
Query: 241 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH 300
VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH
Sbjct: 241 VPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTVPDNTSSARGKEDVNKTLPNLQVVNH 300
Query: 301 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL 360
QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL
Sbjct: 301 QQGPHHRHILKLLPSMEATGGEKSSTPIKGPKRGHPRQNLHKHFDINEHLPWMIVLFLLL 360
Query: 361 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK 420
VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK
Sbjct: 361 VLVVIVVCSIRKSSRTLKKGPRQDPSAIVEKAGLKKSMTPTQNREKWIYYCNGHGIDILK 420
Query: 421 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS 480
LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS
Sbjct: 421 LVAAQVGSQWKDIYQFLCNASEREVAAFSNGYTADHERAYAALQHWTIRGPEASLAQLIS 480
Query: 481 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP 540
ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP
Sbjct: 481 ALRQHRRNDVVEKIRGLMEDTTQLETDKLALPMSPSPLSPSPIPSPNAKLENSALLTVEP 540
Query: 541 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF 600
SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF
Sbjct: 541 SPQDKNKGFFVDESEPLLRCDSTSSGSSALSRNGSFITKEKKDTVLRQVRLDPCDLQPIF 600
Query: 601 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL 655
DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL
Sbjct: 601 DDMLHFLNPEELRVIEEIPQAEDKLDRLFEIIGVKSQEASQTLLDSVYSHLPDLL 655
>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
sapiens]
Length = 461
Score = 120 bits (301), Expect = 4e-27
Identities = 92/305 (30%), Positives = 131/305 (42%), Gaps = 39/305 (12%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
+ C KC G + CT TS VC SC T+T+ N + +C C C +E C
Sbjct: 52 MCCSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCGSRCSSDQVETQACT 111
Query: 125 ALTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSD 178
+R CTC PG + + CAP C G+GV + GTET DV CK CA GTFS+
Sbjct: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171
Query: 179 VPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRP----- 233
SS C+ + C N+V I PG D VC S S + S +PG P+P
Sbjct: 172 TTSSTDICRPHQIC---NVVAI-PGNASMDAVC---TSTSPTRSMAPGAVHLPQPVSTRS 224
Query: 234 EHMETHEVPS-----STYVPKGMNSTESNSSAS--------VRPKVLSSIQEGTVPDNTS 280
+H + PS S +P G + S+ V L + G V
Sbjct: 225 QHTQPTPEPSTAPSTSFLLPMGPSPPAEGSTGDFALPVGLIVGVTALGLLIIGVVNCVIM 284
Query: 281 SARGKEDV----NKTLPNLQV--VNHQQGPHHRHILKLLPSMEATGGEKSSTPI--KGPK 332
+ K+ + +P+L QGP +H+L PS ++ E S++ + + P
Sbjct: 285 TQVKKKPLCLQREAKVPHLPADKARGTQGPEQQHLLITAPSSSSSSLESSASALDRRAPT 344
Query: 333 RGHPR 337
R P+
Sbjct: 345 RNQPQ 349
>gi|14790170 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 115 bits (287), Expect = 2e-25
Identities = 58/169 (34%), Positives = 81/169 (47%)
Query: 53 TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQP 112
TY D TG+ L C +CP GT+V C S C CP +T+ N +E+C C+
Sbjct: 35 TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL 94
Query: 113 CPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCA 172
C E C A +R C C G F C H CP G GV GT +++ +C+ C
Sbjct: 95 CGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCP 154
Query: 173 RGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSST 221
GTFS SS +C+ + +C + L + PG+ D +C + F ST
Sbjct: 155 PGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLST 203
>gi|148743793 osteoprotegerin precursor [Homo sapiens]
Length = 401
Score = 115 bits (287), Expect = 2e-25
Identities = 56/158 (35%), Positives = 77/158 (48%)
Query: 54 YRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPC 113
Y H D T L CDKCP GTY+ +HCT VC+ CP +T + ++C CS C
Sbjct: 28 YLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPVC 87
Query: 114 PWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCAR 173
K C +R C C G + C H CP G+GV + GT + CK+C
Sbjct: 88 KELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPPGFGVVQAGTPERNTVCKRCPD 147
Query: 174 GTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVC 211
G FS+ SS C+ +T+C L++ + G DN+C
Sbjct: 148 GFFSNETSSKAPCRKHTNCSVFGLLLTQKGNATHDNIC 185
>gi|4507585 tumor necrosis factor receptor superfamily, member 6b
[Homo sapiens]
Length = 300
Score = 115 bits (287), Expect = 2e-25
Identities = 58/169 (34%), Positives = 81/169 (47%)
Query: 53 TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQP 112
TY D TG+ L C +CP GT+V C S C CP +T+ N +E+C C+
Sbjct: 35 TYPWRDAETGERLVCAQCPPGTFVQRPCRRDSPTTCGPCPPRHYTQFWNYLERCRYCNVL 94
Query: 113 CPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCA 172
C E C A +R C C G F C H CP G GV GT +++ +C+ C
Sbjct: 95 CGEREEEARACHATHNRACRCRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCP 154
Query: 173 RGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSST 221
GTFS SS +C+ + +C + L + PG+ D +C + F ST
Sbjct: 155 PGTFSASSSSSEQCQPHRNCTALGLALNVPGSSSHDTLCTSCTGFPLST 203
>gi|5730095 tumor necrosis factor receptor superfamily, member 9
precursor [Homo sapiens]
Length = 255
Score = 86.7 bits (213), Expect = 6e-17
Identities = 56/165 (33%), Positives = 76/165 (46%), Gaps = 21/165 (12%)
Query: 67 CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAAL 126
C CPAGT+ C N ++CS CP +F+ G C C Q C + C++
Sbjct: 28 CSNCPAGTF----CDNNRNQICSPCPPNSFSS-AGGQRTCDICRQ-CKGVFRTRKECSST 81
Query: 127 TDRECTCPPGMFQSNATCAP-HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMK 185
++ EC C PG A C+ C G + KKG CK C GTF+D +
Sbjct: 82 SNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKG-------CKDCCFGTFNDQKRGI-- 132
Query: 186 CKAYTDCLSQNLVVIKPGTKETDNVCGTLPS-----FSSSTSPSP 225
C+ +T+C V+ GTKE D VCG P+ SS T P+P
Sbjct: 133 CRPWTNCSLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAP 177
>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
Length = 435
Score = 85.9 bits (211), Expect = 1e-16
Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 9/155 (5%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPC-PWPMIEKL-P 122
+ C +CP GTYVS C+ VC++C ++ H N + C C +PC P +E++ P
Sbjct: 57 ICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLC-RPCDPVMGLEEIAP 115
Query: 123 CAALTDRECTCPPGMFQSN-----ATCAPHTVCPVGWGVRKKGTETE-DVRCKQCARGTF 176
C + +C C PGMF + C + CP G K + + C C G F
Sbjct: 116 CTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHF 175
Query: 177 SDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVC 211
+ S +C+ +T C +Q LV PGT ++D C
Sbjct: 176 QNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTC 210
>gi|23200041 tumor necrosis factor receptor superfamily, member 14
precursor [Homo sapiens]
Length = 283
Score = 77.4 bits (189), Expect = 4e-14
Identities = 44/133 (33%), Positives = 59/133 (44%), Gaps = 8/133 (6%)
Query: 67 CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCP-WPMIEKLPCAA 125
C KC G V E C + VC CP GT+ H NG+ KC C P + C+
Sbjct: 54 CPKCSPGYRVKEACGELTGTVCEPCPPGTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSR 113
Query: 126 LTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDV 179
+ C C PG F A C + G V+K GTE++D C+ C GTFS
Sbjct: 114 TENAVCGCSPGHFCIVQDGDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFSP- 172
Query: 180 PSSVMKCKAYTDC 192
++ +C+ T C
Sbjct: 173 NGTLEECQHQTKC 185
>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
precursor [Homo sapiens]
Length = 616
Score = 77.0 bits (188), Expect = 5e-14
Identities = 54/175 (30%), Positives = 75/175 (42%), Gaps = 12/175 (6%)
Query: 54 YRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPC 113
Y H+ R C+KC G Y+S CT TS VC C + N +KC + C
Sbjct: 40 YEHLGRC------CNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDSWNEEDKCL-LHKVC 92
Query: 114 PW--PMIEKLPCAALTDRECTCPPGMFQSN--ATCAPHTVCPVGWGVRKKGTETEDVRCK 169
++ + + T R C C G S C +T C G G + +D CK
Sbjct: 93 DTGKALVAVVAGNSTTPRRCACTAGYHWSQDCECCRRNTECAPGLGAQHPLQLNKDTVCK 152
Query: 170 QCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKETDNVC-GTLPSFSSSTSP 223
C G FSD SS KC+ +T+C V GT+++D VC +LP+ P
Sbjct: 153 PCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDAVCSSSLPARKPPNEP 207
>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
Length = 277
Score = 76.3 bits (186), Expect = 9e-14
Identities = 48/152 (31%), Positives = 68/152 (44%), Gaps = 8/152 (5%)
Query: 67 CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHD---CSQPCPWPMIEKLPC 123
C C G + CT + C C F N CH C + +K
Sbjct: 38 CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQK--G 95
Query: 124 AALTDRECTCPPGMF---QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP 180
+ TD CTC G ++ +C H C G+GV++ T D C+ C G FS+V
Sbjct: 96 TSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155
Query: 181 SSVMKCKAYTDCLSQNLVVIKPGTKETDNVCG 212
S+ KC +T C +++LVV + GT +TD VCG
Sbjct: 156 SAFEKCHPWTSCETKDLVVQQAGTNKTDVVCG 187
>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
Length = 427
Score = 63.5 bits (153), Expect = 6e-10
Identities = 61/259 (23%), Positives = 93/259 (35%), Gaps = 13/259 (5%)
Query: 21 ATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHC 80
AT + G LLL L + ++A G Y H C C G V++ C
Sbjct: 5 ATGRAMDGPRLLLLLLLGVSLGGAKEACPT-GLYTHSGEC------CKACNLGEGVAQPC 57
Query: 81 TNTSLRVCSSCPVG-TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQ 139
+ VC C TF+ + E C C++ C PC D C C G +Q
Sbjct: 58 -GANQTVCEPCLDSVTFSDVVSATEPCKPCTE-CVGLQSMSAPCVEADDAVCRCAYGYYQ 115
Query: 140 SNAT--CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNL 197
T C VC G G+ + ++ C++C GT+SD + V C T C
Sbjct: 116 DETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC-EDTE 174
Query: 198 VVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMNSTESN 257
++ T+ D C +P + S P + P E P + + +
Sbjct: 175 RQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTT 234
Query: 258 SSASVRPKVLSSIQEGTVP 276
S +P V + +P
Sbjct: 235 VMGSSQPVVTRGTTDNLIP 253
>gi|68348711 tumor necrosis factor receptor superfamily, member 8
isoform 1 precursor [Homo sapiens]
Length = 595
Score = 62.4 bits (150), Expect = 1e-09
Identities = 38/127 (29%), Positives = 55/127 (43%), Gaps = 10/127 (7%)
Query: 67 CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAAL 126
C +CP G + ++ C C + + C CS+ ++EK PCA
Sbjct: 45 CYRCPMGLFPTQQCPQRPTDCRKQCEPDYYLDEADRCTACVTCSRD---DLVEKTPCAWN 101
Query: 127 TDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP 180
+ R C C PGMF S A C H+VCP G V+ GT ++ C+ + G S
Sbjct: 102 SSRVCECRPGMFCSTSAVNSCARCFFHSVCPAGMIVKFPGTAQKNTVCEPASPGV-SPAC 160
Query: 181 SSVMKCK 187
+S CK
Sbjct: 161 ASPENCK 167
Score = 39.3 bits (90), Expect = 0.012
Identities = 23/79 (29%), Positives = 33/79 (41%), Gaps = 9/79 (11%)
Query: 106 CHDCSQPCPWPMIEKLPCAALTDRECTCPPGMF------QSNATCAPHTVCPVGWGVRKK 159
C CS+ ++EK PCA + R C C PGM S A C P+ +C + +
Sbjct: 259 CVSCSRD---DLVEKTPCAWNSSRTCECRPGMICATSATNSRARCVPYPICAAETVTKPQ 315
Query: 160 GTETEDVRCKQCARGTFSD 178
+D + GT D
Sbjct: 316 DMAEKDTTFEAPPLGTQPD 334
>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
Length = 203
Score = 54.3 bits (129), Expect = 3e-07
Identities = 37/130 (28%), Positives = 52/130 (40%), Gaps = 8/130 (6%)
Query: 67 CDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHD---CSQPCPWPMIEKLPC 123
C C G + CT + C C F N CH C + +K
Sbjct: 38 CSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCDPNLGLRVQQK--G 95
Query: 124 AALTDRECTCPPGMF---QSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP 180
+ TD CTC G ++ +C H C G+GV++ T D C+ C G FS+V
Sbjct: 96 TSETDTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGFFSNVS 155
Query: 181 SSVMKCKAYT 190
S+ KC +T
Sbjct: 156 SAFEKCHPWT 165
Score = 32.7 bits (73), Expect = 1.1
Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 3/80 (3%)
Query: 133 CPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDC 192
C + N+ C ++C G + TE + C C F D + C + C
Sbjct: 26 CREKQYLINSQCC--SLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYC 83
Query: 193 -LSQNLVVIKPGTKETDNVC 211
+ L V + GT ETD +C
Sbjct: 84 DPNLGLRVQQKGTSETDTIC 103
>gi|22547121 tumor necrosis factor receptor superfamily, member 10c
precursor [Homo sapiens]
Length = 259
Score = 53.9 bits (128), Expect = 5e-07
Identities = 59/232 (25%), Positives = 86/232 (37%), Gaps = 45/232 (19%)
Query: 25 MIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTS 84
+I LL + S TTA+ E+ + + G+ +CPAG++ SEH
Sbjct: 13 VIVAVLLPVLAYSATTARQEEVPQQTVAPQQQRHSFKGE-----ECPAGSHRSEH----- 62
Query: 85 LRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNAT 143
C+ C G +T N C C+ C K C D C C G F++
Sbjct: 63 TGACNPCTEGVDYTNASNNEPSCFPCT-VCKSDQKHKSSCTMTRDTVCQCKEGTFRN--- 118
Query: 144 CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTD--CLSQ---NLV 198
E C++C+R +V V C ++ D C+ + N
Sbjct: 119 ------------------ENSPEMCRKCSRCPSGEV--QVSNCTSWDDIQCVEEFGANAT 158
Query: 199 VIKPGTKETDNVC-GT-LPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVP 248
V P +ET N GT P+ + + SPGT P P ET T P
Sbjct: 159 VETPAAEETMNTSPGTPAPAAEETMNTSPGT---PAPAAEETMTTSPGTPAP 207
>gi|4759246 tumor necrosis factor receptor superfamily, member 18
isoform 1 precursor [Homo sapiens]
Length = 241
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 130 ECTCPPGMFQSNATCAP---HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKC 186
+C C F C H CP G GV+ +G + +C CA GTFS C
Sbjct: 71 DCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HC 128
Query: 187 KAYTDCLSQNLVVIKPGTKETDNVC 211
K +TDC + + PG K + VC
Sbjct: 129 KPWTDCTQFGFLTVFPGNKTHNAVC 153
>gi|23238197 tumor necrosis factor receptor superfamily, member 18
isoform 3 precursor [Homo sapiens]
Length = 234
Score = 50.4 bits (119), Expect = 5e-06
Identities = 28/85 (32%), Positives = 37/85 (43%), Gaps = 5/85 (5%)
Query: 130 ECTCPPGMFQSNATCAP---HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKC 186
+C C F C H CP G GV+ +G + +C CA GTFS C
Sbjct: 71 DCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HC 128
Query: 187 KAYTDCLSQNLVVIKPGTKETDNVC 211
K +TDC + + PG K + VC
Sbjct: 129 KPWTDCTQFGFLTVFPGNKTHNAVC 153
>gi|4507579 tumor necrosis factor receptor superfamily, member 4
precursor [Homo sapiens]
Length = 277
Score = 50.1 bits (118), Expect = 7e-06
Identities = 48/185 (25%), Positives = 72/185 (38%), Gaps = 35/185 (18%)
Query: 29 SLLLLGF-LSTTTAQPEQKASNLIG-TYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLR 86
+LLLLG LST T + +G TY DR C +C G + C+ +
Sbjct: 15 ALLLLGLGLSTVTGL------HCVGDTYPSNDRC------CHECRPGNGMVSRCSRSQNT 62
Query: 87 VCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAP 146
VC C G + N + C +PC W + + ++R+ C T
Sbjct: 63 VCRPCGPGFY----NDVVSSKPC-KPCTWCNLR-----SGSERKQLC---------TATQ 103
Query: 147 HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNLVVIKPGTKE 206
TVC G + + V C C G FS P CK +T+C ++P +
Sbjct: 104 DTVCRCRAGTQPLDSYKPGVDCAPCPPGHFS--PGDNQACKPWTNCTLAGKHTLQPASNS 161
Query: 207 TDNVC 211
+D +C
Sbjct: 162 SDAIC 166
>gi|134031945 SCO-spondin [Homo sapiens]
Length = 5147
Score = 49.7 bits (117), Expect = 9e-06
Identities = 24/66 (36%), Positives = 31/66 (46%), Gaps = 6/66 (9%)
Query: 89 SSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLP---CAALTDRECTCPPGMFQSNATCA 145
+ CP R E+CH PCP + + P C CTCPPG+F NA+C
Sbjct: 2884 AQCPENMLFR---SAEQCHQEGGPCPRLCLTQGPGIECTGFCAPGCTCPPGLFLHNASCL 2940
Query: 146 PHTVCP 151
P + CP
Sbjct: 2941 PRSQCP 2946
Score = 37.4 bits (85), Expect = 0.044
Identities = 33/137 (24%), Positives = 49/137 (35%), Gaps = 24/137 (17%)
Query: 71 PAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRE 130
P +E +L+ C CP G + C+ CP P A
Sbjct: 4798 PCQAQDTEQRQECNLQPCPECPPG---------QVLSACATSCPCLCWHLQPGAICVQEP 4848
Query: 131 CT----CPPGMFQSNATCAPHTVCP-----VGWGVRKKGTETEDVRCKQCARGTFSDVPS 181
C CP G N TC P T CP + WG+ T T + + ++ GT +
Sbjct: 4849 CQPGCGCPGGQLLHNGTCVPPTACPCTQHSLPWGL----TLTLEEQAQELPPGTV--LTR 4902
Query: 182 SVMKCKAYTDCLSQNLV 198
+ +C + S +LV
Sbjct: 4903 NCTRCVCHGGAFSCSLV 4919
Score = 34.7 bits (78), Expect = 0.29
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 22/149 (14%)
Query: 71 PAGTYVSEHCT---------NTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKL 121
P GT ++ +CT + SL C P T+ + G + C Q C K
Sbjct: 4895 PPGTVLTRNCTRCVCHGGAFSCSLVDCQVPPGETWQQVAPG--ELGLCEQTCLEMNATKT 4952
Query: 122 P--CAALTDRECTCPPGMFQSNA-TCAPHTVCPVGWGVRK---KGTETEDVRCKQCARGT 175
C++ C C PG F+S A C P C W + + G+E ++ C+ C
Sbjct: 4953 QSNCSSARASGCVCQPGHFRSQAGPCVPEDHCEC-WHLGRPHLPGSEWQEA-CESCL--C 5008
Query: 176 FSDVPSSVMKCKAYTDCLSQNLVVIKPGT 204
S P C T C +V++PG+
Sbjct: 5009 LSGRPVCTQHCSPLT-CAQGEEMVLEPGS 5036
Score = 34.3 bits (77), Expect = 0.37
Identities = 22/87 (25%), Positives = 28/87 (32%), Gaps = 16/87 (18%)
Query: 70 CPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAAL--- 126
CP S C S + C+ C G + H C QPCP + P +
Sbjct: 3509 CPGNHTQSRPCQENSTQ-CTDC---------GGGQSLHPCGQPCPRSCQDLSPGSVCQPG 3558
Query: 127 ---TDRECTCPPGMFQSNATCAPHTVC 150
C CP G + C P C
Sbjct: 3559 SVGCQPTCGCPLGQLSQDGLCVPPAHC 3585
Score = 33.9 bits (76), Expect = 0.49
Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 5/65 (7%)
Query: 112 PCPWPMIE---KLPCAALTDRECTCPPGMFQSNATCAPHTVCP--VGWGVRKKGTETEDV 166
PCP ++ C+ C CPPG+ + C P + CP VG ++ G
Sbjct: 2634 PCPPSCLDPKANRSCSGHCVEGCRCPPGLLLHDTRCLPLSECPCLVGEELKWPGVSFLLG 2693
Query: 167 RCKQC 171
C QC
Sbjct: 2694 NCSQC 2698
Score = 33.5 bits (75), Expect = 0.64
Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 12/99 (12%)
Query: 52 GTYRHVDRATGQVL-----TCDKCPAGTYVSEHCTNTSLR--VCSS--CPVGTFTRHENG 102
G + H R+ G L CD+ P + ++C + VC + CPV T E
Sbjct: 3259 GPWSHCSRSCGGGLRSRTRACDQ-PPPQGLGDYCEGPRAQGEVCQALPCPVTNCTAIEGA 3317
Query: 103 IEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQSN 141
+ C PCP + + C C CPPG S+
Sbjct: 3318 --EYSPCGPPCPRSCDDLVHCVWRCQPGCYCPPGQVLSS 3354
Score = 33.5 bits (75), Expect = 0.64
Identities = 21/78 (26%), Positives = 28/78 (35%), Gaps = 5/78 (6%)
Query: 112 PCPWPMIEKLPCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQ- 170
PCP P + C+ RE CP G C P CP + C++
Sbjct: 3676 PCPGPARQSRTCSTQVCREAGCPAGRLYRE--CQPGEGCPFSCAHVTQQVGCFSEGCEEG 3733
Query: 171 --CARGTFSDVPSSVMKC 186
C GTF + V +C
Sbjct: 3734 CHCPEGTFQHRLACVQEC 3751
Score = 32.3 bits (72), Expect = 1.4
Identities = 17/54 (31%), Positives = 22/54 (40%), Gaps = 12/54 (22%)
Query: 108 DCSQPCP------WPMIEKL--PCAALTDRECTCPPGMFQSNATCAPHTVCPVG 153
DC+ CP W ++ L PC C CPPG + C P + C G
Sbjct: 4677 DCANQCPHSCADLWDRVQCLQGPCRP----GCRCPPGQLVQDGRCVPISSCRCG 4726
Score = 30.4 bits (67), Expect = 5.4
Identities = 40/184 (21%), Positives = 65/184 (35%), Gaps = 27/184 (14%)
Query: 2 GTSPSSSTALAS-CSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRA 60
G PS +AL S C+ ++R A ++L Q+ L+ R
Sbjct: 732 GRCPSEDSALLSPCTTHSQRHAFAEAACAILHSSVF--------QECHRLVDKEPFYLRC 783
Query: 61 TGQVLTCDK-----CPAGTYVSEHCTNTSL----RVCSSCPVGTFTRHENGIEKCHDCSQ 111
V CD CP + + C R + CPV G ++ +C+
Sbjct: 784 LAAVCGCDPGSDCLCPVLSAYARRCAQEGASPPWRNQTLCPVMC-----PGGQEYRECAP 838
Query: 112 PCPWPMIEKLPCAALTD--RECTCPPGM-FQSNATCAPHTVCPVGWGVRKKGTETEDVR- 167
C + C L C CP G+ + C P ++CP G R+ + ++
Sbjct: 839 ACGQHCGKPEDCGELGSCVAGCNCPLGLLWDPEGQCVPPSLCPCQLGARRYAPGSATMKE 898
Query: 168 CKQC 171
C +C
Sbjct: 899 CNRC 902
Score = 30.4 bits (67), Expect = 5.4
Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 13/101 (12%)
Query: 70 CPAGTYVSEHCTNTSLRVC--SSCPVGTFTRHENGIEKC-HDCSQPCPWPMIEKLPCAAL 126
CP S C S +VC + CP G R E C C+ + +++ C +
Sbjct: 3677 CPGPARQSRTC---STQVCREAGCPAGRLYRECQPGEGCPFSCAH-----VTQQVGCFSE 3728
Query: 127 TDRE-CTCPPGMFQSNATCAPHTVCPV-GWGVRKKGTETED 165
E C CP G FQ C C + W +++ G D
Sbjct: 3729 GCEEGCHCPEGTFQHRLACVQECPCVLTAWLLQELGATIGD 3769
Score = 30.0 bits (66), Expect = 7.0
Identities = 22/74 (29%), Positives = 27/74 (36%), Gaps = 4/74 (5%)
Query: 80 CTNTSLRVCSS--CPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGM 137
C L C++ CP F E + C C P A TD C CPPG
Sbjct: 904 CQERGLWNCTARHCPSQAFCPREL-VYAPGACLLTCDSPSANHSCPAGSTDG-CVCPPGT 961
Query: 138 FQSNATCAPHTVCP 151
+ C P +CP
Sbjct: 962 VLLDERCVPPDLCP 975
Score = 29.6 bits (65), Expect = 9.2
Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 10/72 (13%)
Query: 108 DCSQPCPWPMIEKL------PCAALTDRECTCPPGMFQSNATCAPHTVCPVGWGVRKKGT 161
DC CP P E + C C CP G+F + C P CP + R++
Sbjct: 477 DCVSLCP-PSCEAVGQGEEESCREECVSGCECPRGLFWNGTLCVPAAHCPC-YYCRQRYV 534
Query: 162 ETEDVR--CKQC 171
+ VR C C
Sbjct: 535 PGDTVRQLCNPC 546
>gi|23200023 tumor necrosis factor receptor superfamily, member 25
isoform 3 precursor [Homo sapiens]
Length = 380
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 67 CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121
C CPAG Y+ CT C CP TF H + +C C + +E
Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
Query: 122 PCAALTDRECTCPPGMF 138
C+A+ D C C PG F
Sbjct: 107 -CSAVADTRCGCKPGWF 122
>gi|23200021 tumor necrosis factor receptor superfamily, member 25
isoform 1 precursor [Homo sapiens]
Length = 426
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 67 CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121
C CPAG Y+ CT C CP TF H + +C C + +E
Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
Query: 122 PCAALTDRECTCPPGMF 138
C+A+ D C C PG F
Sbjct: 107 -CSAVADTRCGCKPGWF 122
>gi|89142745 tumor necrosis factor receptor superfamily, member 25
isoform 12 precursor [Homo sapiens]
Length = 181
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 67 CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121
C CPAG Y+ CT C CP TF H + +C C + +E
Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
Query: 122 PCAALTDRECTCPPGMF 138
C+A+ D C C PG F
Sbjct: 107 -CSAVADTRCGCKPGWF 122
>gi|4507569 tumor necrosis factor receptor superfamily, member 25
isoform 2 precursor [Homo sapiens]
Length = 417
Score = 47.0 bits (110), Expect = 6e-05
Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)
Query: 67 CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121
C CPAG Y+ CT C CP TF H + +C C + +E
Sbjct: 48 CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
Query: 122 PCAALTDRECTCPPGMF 138
C+A+ D C C PG F
Sbjct: 107 -CSAVADTRCGCKPGWF 122
>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
isoform 2 precursor [Homo sapiens]
Length = 411
Score = 46.2 bits (108), Expect = 9e-05
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
L C +C +G CT T VC C GTF R E+ E C C CP M++ C
Sbjct: 114 LRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGMVKVGDCT 171
Query: 125 ALTDREC 131
+D EC
Sbjct: 172 PWSDIEC 178
Score = 39.3 bits (90), Expect = 0.012
Identities = 44/163 (26%), Positives = 61/163 (37%), Gaps = 12/163 (7%)
Query: 70 CPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAALTD 128
CP G ++SE R C SC G ++ H N + C C++ C +E PC +
Sbjct: 81 CPPGHHISEDG-----RDCISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
Query: 129 RECTCPPGMFQ---SNATCAP-HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVP-SSV 183
C C G F+ S C T CP G T D+ C G V ++V
Sbjct: 135 TVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKESGIIIGVTVAAV 194
Query: 184 MKCKAYTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPG 226
+ A C S + P K + G P +S PG
Sbjct: 195 VLIVAVFVCKSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPG 237
>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
isoform 1 precursor [Homo sapiens]
Length = 440
Score = 46.2 bits (108), Expect = 9e-05
Identities = 25/67 (37%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
L C +C +G CT T VC C GTF R E+ E C C CP M++ C
Sbjct: 114 LRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTF-REEDSPEMCRKCRTGCPRGMVKVGDCT 171
Query: 125 ALTDREC 131
+D EC
Sbjct: 172 PWSDIEC 178
Score = 43.1 bits (100), Expect = 8e-04
Identities = 40/163 (24%), Positives = 60/163 (36%), Gaps = 36/163 (22%)
Query: 70 CPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAALTD 128
CP G ++SE R C SC G ++ H N + C C++ C +E PC +
Sbjct: 81 CPPGHHISEDG-----RDCISCKYGQDYSTHWNDLLFCLRCTR-CDSGEVELSPCTTTRN 134
Query: 129 RECTCPPGMFQSNATCAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKA 188
C C G F+ E C++C G P ++K
Sbjct: 135 TVCQCEEGTFRE---------------------EDSPEMCRKCRTG----CPRGMVKVGD 169
Query: 189 YTDCLSQNLVVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFP 231
T V + GTK + G +P+ + + SPGT P
Sbjct: 170 CTPWSDIECVHKESGTKHS----GEVPAVEETVTSSPGTPASP 208
>gi|21361086 tumor necrosis factor receptor superfamily, member 10a
[Homo sapiens]
Length = 468
Score = 46.2 bits (108), Expect = 9e-05
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 2/67 (2%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
L C C + CT T C C GTF R++N E C CS+ CP M++ C
Sbjct: 165 LPCTACKSDEEERSPCTTTRNTACQ-CKPGTF-RNDNSAEMCRKCSRGCPRGMVKVKDCT 222
Query: 125 ALTDREC 131
+D EC
Sbjct: 223 PWSDIEC 229
Score = 43.5 bits (101), Expect = 6e-04
Identities = 41/172 (23%), Positives = 66/172 (38%), Gaps = 18/172 (10%)
Query: 2 GTSPSSSTALASCSRIARRATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRAT 61
G +P A + R+ T + +LL + ++A + IGT +
Sbjct: 71 GRAPGPRPAREASPRLRVHKTFKFVVVGVLLQ--VVPSSAATIKLHDQSIGTQQWEHSPL 128
Query: 62 GQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEK 120
G++ CP G++ SEH C+ C G +T N + C C+ C E+
Sbjct: 129 GEL-----CPPGSHRSEHPG-----ACNRCTEGVGYTNASNNLFACLPCTA-CKSDEEER 177
Query: 121 LPCAALTDRECTCPPGMFQSNATCAP----HTVCPVGWGVRKKGTETEDVRC 168
PC + C C PG F+++ + CP G K T D+ C
Sbjct: 178 SPCTTTRNTACQCKPGTFRNDNSAEMCRKCSRGCPRGMVKVKDCTPWSDIEC 229
>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
precursor [Homo sapiens]
Length = 386
Score = 44.3 bits (103), Expect = 4e-04
Identities = 32/109 (29%), Positives = 43/109 (39%), Gaps = 15/109 (13%)
Query: 68 DKCPAGTYVSEHCTNTSLRVCSSCPVGT-FTRHENGIEKCHDCSQPCPWPMIEKLPCAAL 126
++CPAG++ SE+ C+ C G +T N + C C+ C K C
Sbjct: 81 EECPAGSHRSEYTG-----ACNPCTEGVDYTIASNNLPSCLLCTV-CKSGQTNKSSCTTT 134
Query: 127 TDRECTCPPGMFQSN------ATCAPHTVCPVGWGVRKKGTETEDVRCK 169
D C C G FQ TC T CP G T D++CK
Sbjct: 135 RDTVCQCEKGSFQDKNSPEMCRTC--RTGCPRGMVKVSNCTPRSDIKCK 181
Score = 40.4 bits (93), Expect = 0.005
Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCA 124
L C C +G CT T VC C G+F + +N E C C CP M++ C
Sbjct: 116 LLCTVCKSGQTNKSSCTTTRDTVCQ-CEKGSF-QDKNSPEMCRTCRTGCPRGMVKVSNCT 173
Query: 125 ALTDREC 131
+D +C
Sbjct: 174 PRSDIKC 180
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 41.6 bits (96), Expect = 0.002
Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 4/78 (5%)
Query: 65 LTCDKCPAGTYVSEHCTNTSLRV-CSSCPVGTFTRHENGIEKCHDCSQPCPWPM--IEKL 121
+ C KC GTY+ C C C G+FT EN + C CS+ C M +E
Sbjct: 57 ICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLRHCLSCSK-CRKEMGQVEIS 115
Query: 122 PCAALTDRECTCPPGMFQ 139
C D C C ++
Sbjct: 116 SCTVDRDTVCGCRKNQYR 133
Score = 34.3 bits (77), Expect = 0.37
Identities = 24/89 (26%), Positives = 40/89 (44%), Gaps = 7/89 (7%)
Query: 129 RECTCPPGMF---QSNATCAPHTVCPVGWGVRKKGTET-EDVRCKQCARGTFSDVPSSVM 184
R+ CP G + Q+N+ C T C G + +D C++C G+F+ + +
Sbjct: 40 RDSVCPQGKYIHPQNNSICC--TKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR 97
Query: 185 KCKAYTDCLSQ-NLVVIKPGTKETDNVCG 212
C + + C + V I T + D VCG
Sbjct: 98 HCLSCSKCRKEMGQVEISSCTVDRDTVCG 126
>gi|23238194 tumor necrosis factor receptor superfamily, member 18
isoform 2 precursor [Homo sapiens]
Length = 255
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/66 (34%), Positives = 29/66 (43%), Gaps = 5/66 (7%)
Query: 130 ECTCPPGMFQSNATCAP---HTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKC 186
+C C F C H CP G GV+ +G + +C CA GTFS C
Sbjct: 71 DCMCVQPEFHCGDPCCTTCRHHPCPPGQGVQSQGKFSFGFQCIDCASGTFSGGHEG--HC 128
Query: 187 KAYTDC 192
K +TDC
Sbjct: 129 KPWTDC 134
>gi|31377568 signal peptide, CUB domain, EGF-like 3 [Homo sapiens]
Length = 993
Score = 36.6 bits (83), Expect = 0.075
Identities = 48/171 (28%), Positives = 63/171 (36%), Gaps = 37/171 (21%)
Query: 52 GTYRHVDRATGQVLTCDKCPAGTYVSEHCTNTSLRVCSSCPVGTFTRHENGIEKCHDCSQ 111
GTY H GQ C CPAGT+ C CP G+ G C+
Sbjct: 642 GTYYH-----GQTEQCVPCPAGTFQERE----GQLSCDLCP-GSDAHGPLGATNVTTCAG 691
Query: 112 PCPWPMIEKL----PCAALTDRECTCPPGMFQSNATCAPHTVC-PVGWGVRKK---GTET 163
CP P + PC CP G +Q A T+C P G G+ K
Sbjct: 692 QCP-PGQHSVDGFKPCQ-------PCPRGTYQPE---AGRTLCFPCGGGLTTKHEGAISF 740
Query: 164 EDVRCK-QCARGTFSDVPSSVMKC-----KAYTDCLSQNLVVIKPGTKETD 208
+D K QC+ G + + +S+ +C +Y QN PG TD
Sbjct: 741 QDCDTKVQCSPGHYYN--TSIHRCIRCAMGSYQPDFRQNFCSRCPGNTSTD 789
>gi|112382214 SEC24 (S. cerevisiae) homolog B isoform b [Homo
sapiens]
Length = 1233
Score = 36.2 bits (82), Expect = 0.098
Identities = 23/67 (34%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 216 SFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMNSTESNSSASVRPKVLSSIQEGTV 275
S SS++ +P TA P E + + PS KG++S+ + SSAS P +++ G+
Sbjct: 321 SSGSSSTRTPPTANHP-VEPVTSVTQPSELLQQKGVDSSSTTSSASPMPNSYDALEGGSY 379
Query: 276 PDNTSSA 282
PD SS+
Sbjct: 380 PDMLSSS 386
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.130 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,676,183
Number of Sequences: 37866
Number of extensions: 1410357
Number of successful extensions: 6695
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 118
Number of HSP's that attempted gapping in prelim test: 6365
Number of HSP's gapped (non-prelim): 387
length of query: 655
length of database: 18,247,518
effective HSP length: 109
effective length of query: 546
effective length of database: 14,120,124
effective search space: 7709587704
effective search space used: 7709587704
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.