Search of human proteins with 64084766

Search of human proteins with 64084766

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|64084766 fidgetin [Homo sapiens]
         (759 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|64084766 fidgetin [Homo sapiens]                                  1537   0.0  
gi|116292174 fidgetin-like 2 [Homo sapiens]                           455   e-128
gi|31742536 fidgetin-like 1 [Homo sapiens]                            382   e-106
gi|112789543 fidgetin-like 1 [Homo sapiens]                           382   e-106
gi|40806170 spastin isoform 2 [Homo sapiens]                          244   2e-64
gi|11875211 spastin isoform 1 [Homo sapiens]                          242   1e-63
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     186   5e-47
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]              180   4e-45
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               180   4e-45
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               180   4e-45
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]         169   1e-41
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]          167   4e-41
gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]     145   2e-34
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              122   2e-27
gi|6005942 valosin-containing protein [Homo sapiens]                  119   1e-26
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            118   2e-26
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            116   9e-26
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 115   2e-25
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 115   2e-25
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            113   7e-25
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           110   6e-24
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       108   2e-23
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   108   2e-23
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   108   2e-23
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   108   2e-23
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   104   3e-22
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     102   1e-21
gi|4505725 peroxin1 [Homo sapiens]                                    101   3e-21
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           100   5e-21
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             100   5e-21

>gi|64084766 fidgetin [Homo sapiens]
          Length = 759

 Score = 1537 bits (3979), Expect = 0.0
 Identities = 759/759 (100%), Positives = 759/759 (100%)

Query: 1   MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS 60
           MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS
Sbjct: 1   MISSTSVYGLKMQWTPEHAQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDIS 60

Query: 61  ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP 120
           ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP
Sbjct: 61  ALTASNLLKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYP 120

Query: 121 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL 180
           MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL
Sbjct: 121 MNCVPDVITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGL 180

Query: 181 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS 240
           PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS
Sbjct: 181 PSQEYAPGYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTS 240

Query: 241 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL 300
           NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL
Sbjct: 241 NLSSYSYPSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGL 300

Query: 301 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN 360
           TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN
Sbjct: 301 TPIAPSALTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTN 360

Query: 361 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG 420
           RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG
Sbjct: 361 RGNGFDRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFG 420

Query: 421 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG 480
           KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG
Sbjct: 421 KYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG 480

Query: 481 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA 540
           PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA
Sbjct: 481 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIA 540

Query: 541 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS 600
           SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS
Sbjct: 541 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS 600

Query: 601 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ 660
           PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ
Sbjct: 601 PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQ 660

Query: 661 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ 720
           IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ
Sbjct: 661 IIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQ 720

Query: 721 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ 759
           LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ
Sbjct: 721 LRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCSQ 759


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score =  455 bits (1171), Expect = e-128
 Identities = 288/751 (38%), Positives = 396/751 (52%), Gaps = 107/751 (14%)

Query: 12  MQWTPEHAQ----WPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNL 67
           M WTPEHAQ    WPEQH D++STT SPAHK+E   G  QR + YAWA+DDISALTASNL
Sbjct: 1   MHWTPEHAQPLNQWPEQHLDVSSTTPSPAHKLELPPGGRQRCH-YAWAHDDISALTASNL 59

Query: 68  LKKYAEKYSGILEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDV 127
           LK+YAEKYSG+L+ P +RP L  YSD  +  +NG K + EPW      E  YP+  + + 
Sbjct: 60  LKRYAEKYSGVLDSPYERPALGGYSD--ASFLNGAKGDPEPWP---GPEPPYPLASLHEG 114

Query: 128 ITASKAGVSSALPPADVSASIGSSPGVASNLTEPSYSSSTCGSHTVPSLHAGLPSQEYAP 187
           +  +K+G          S ++G SP +A NL EP Y+ + CG  +         + EYA 
Sbjct: 115 LPGTKSGGGGG------SGALGGSPVLAGNLPEPLYAGNACGGPSA--------APEYAA 160

Query: 188 GYNGSYLHSTYSSQPAPALPSPHPSPLHSSGLLQPPPPPPPPPALVPGYNGTSNLSSYSY 247
           GY G YL   Y +Q   ALP P P+      LLQPPPPP        GY  ++ L  Y+Y
Sbjct: 161 GYGGGYLAPGYCAQTGAALPPPPPA-----ALLQPPPPP--------GYGPSAPL--YNY 205

Query: 248 PSASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPIAPSA 307
           P+  Y  Q   G+   P G  PPP+ YL  G+PAPTPLP    P      +G    AP A
Sbjct: 206 PAGGYAAQPGYGALPPPPG--PPPAPYLTPGLPAPTPLPAPAPP----TAYGFPTAAPGA 259

Query: 308 LTNSSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRS--TQSPMYRMPDNSISNTNRGNGF 365
               S  SLKRKA   A +G  +  Y  Y+Y   ++       Y   DN      RGNGF
Sbjct: 260 ---ESGLSLKRKA---ADEGP-EGRYRKYAYEPAKAPVADGASYPAADNGEC---RGNGF 309

Query: 366 DRSAETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSP 425
                                          RA  P +   A    G           SP
Sbjct: 310 -------------------------------RAKPPGAAEEASGKYGG--GVPLKVLGSP 336

Query: 426 VMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDW 485
           V   +G +       P + P  R   +      E  K  D   ++LVT++++  GPPV W
Sbjct: 337 V---YGPQLEPFEKFPERAPAPRGGFAVPSG--ETPKGVDPGALELVTSKMVDCGPPVQW 391

Query: 486 NDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGA 545
            D+AG   +KA ++EE++WP+LR  A+ G    PR++LLFGPRG GK LLGRC+A+QLGA
Sbjct: 392 ADVAGQGALKAALEEELVWPLLRPPAYPGSLRPPRTVLLFGPRGAGKALLGRCLATQLGA 451

Query: 546 TFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRM 605
           T  ++ G+ L A    E  +++ A+F  ARCR PSV+ +S+++ LL ++ ++  +    +
Sbjct: 452 TLLRLRGATLAAPGAAEGARLLQAAFAAARCRPPSVLLISELEALLPAR-DDGAAAGGAL 510

Query: 606 RTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQL 665
           +   L  LD    +  D ++V+  TS+P  +DE+ RR F  R  + LPDS AR QI+ + 
Sbjct: 511 QVPLLACLDGGCGAGADGVLVVGTTSRPAALDEATRRRFSLRFYVALPDSPARGQILQRA 570

Query: 666 LSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVT 725
           L+Q    L+++E A LVQ T+GFSG ++  LCQ+A  G           A +P   RP++
Sbjct: 571 LAQQGCALSERELAALVQGTQGFSGGELGQLCQQAAAG-----------AGLPGLQRPLS 619

Query: 726 YQDFENAFCKIQPSISQKELDMYVEWNKMFG 756
           Y+D E A  K+ P  S KELD +VEW+KM+G
Sbjct: 620 YKDLEAALAKVGPRASAKELDSFVEWDKMYG 650


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  382 bits (982), Expect = e-106
 Identities = 192/392 (48%), Positives = 271/392 (69%), Gaps = 7/392 (1%)

Query: 370 ETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSESFGKYTSPVM 427
           E SSL  FK  K+ +  +QQ+K+  Q  RA +  SY   K SLG SRS    GK+  P+ 
Sbjct: 288 EDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRGILGKFVPPIP 345

Query: 428 SEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWND 487
            + G E    +     G G    T   H VDE+LKN +  +I+L+ NEI+  GPPV+W D
Sbjct: 346 KQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWED 402

Query: 488 IAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATF 547
           IAG++  KA IKE V+WP+LR D F+GL   P+ ILLFGP GTGKTL+G+CIASQ GATF
Sbjct: 403 IAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATF 462

Query: 548 FKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRT 607
           F I+ S L +KW+GE EK++ A F VARC+QP+VIF+ +ID LLS + + EH    R++T
Sbjct: 463 FSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKT 522

Query: 608 EFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLS 667
           EFL+QLD   TS+ED+I+V+ AT++P+EIDE+ RR  +KRL IPLP+++AR QI++ L+S
Sbjct: 523 EFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMS 582

Query: 668 QHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQ 727
           +   CL+++E   +VQ+++ FSG D+  LC+EA +GP+ ++   D++ I P Q+RP+ Y 
Sbjct: 583 KEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYI 642

Query: 728 DFENAFCKIQPSISQKELDMYVEWNKMFGCSQ 759
           DFENAF  ++PS+S K+L++Y  WNK FGC +
Sbjct: 643 DFENAFRTVRPSVSPKDLELYENWNKTFGCGK 674



 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 54/152 (35%), Positives = 80/152 (52%), Gaps = 7/152 (4%)

Query: 19  AQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGI 78
           ++W + +F ITS   +   K +AYR  + R  QYAWAN +IS + A+ L KKYAEKYS I
Sbjct: 12  SEWQKNYFAITSGICT-GPKADAYRAQILRI-QYAWANSEISQVCATKLFKKYAEKYSAI 69

Query: 79  LEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSA 138
           ++       L+NY++    L   ++ +S+ WQ  L+   V+ M+ V  ++ A K    S 
Sbjct: 70  IDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSL 129

Query: 139 LPPADVSASIGSSPGVASNLTEPSYSSSTCGS 170
           L PA  S  I      A+    P +  S CGS
Sbjct: 130 LEPALASVVIHKE---ATVFDLPKF--SVCGS 156


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  382 bits (982), Expect = e-106
 Identities = 192/392 (48%), Positives = 271/392 (69%), Gaps = 7/392 (1%)

Query: 370 ETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSESFGKYTSPVM 427
           E SSL  FK  K+ +  +QQ+K+  Q  RA +  SY   K SLG SRS    GK+  P+ 
Sbjct: 288 EDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRGILGKFVPPIP 345

Query: 428 SEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWND 487
            + G E    +     G G    T   H VDE+LKN +  +I+L+ NEI+  GPPV+W D
Sbjct: 346 KQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWED 402

Query: 488 IAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATF 547
           IAG++  KA IKE V+WP+LR D F+GL   P+ ILLFGP GTGKTL+G+CIASQ GATF
Sbjct: 403 IAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATF 462

Query: 548 FKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRT 607
           F I+ S L +KW+GE EK++ A F VARC+QP+VIF+ +ID LLS + + EH    R++T
Sbjct: 463 FSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKT 522

Query: 608 EFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLS 667
           EFL+QLD   TS+ED+I+V+ AT++P+EIDE+ RR  +KRL IPLP+++AR QI++ L+S
Sbjct: 523 EFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMS 582

Query: 668 QHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQ 727
           +   CL+++E   +VQ+++ FSG D+  LC+EA +GP+ ++   D++ I P Q+RP+ Y 
Sbjct: 583 KEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYI 642

Query: 728 DFENAFCKIQPSISQKELDMYVEWNKMFGCSQ 759
           DFENAF  ++PS+S K+L++Y  WNK FGC +
Sbjct: 643 DFENAFRTVRPSVSPKDLELYENWNKTFGCGK 674



 Score = 83.2 bits (204), Expect = 8e-16
 Identities = 54/152 (35%), Positives = 80/152 (52%), Gaps = 7/152 (4%)

Query: 19  AQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGI 78
           ++W + +F ITS   +   K +AYR  + R  QYAWAN +IS + A+ L KKYAEKYS I
Sbjct: 12  SEWQKNYFAITSGICT-GPKADAYRAQILRI-QYAWANSEISQVCATKLFKKYAEKYSAI 69

Query: 79  LEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSA 138
           ++       L+NY++    L   ++ +S+ WQ  L+   V+ M+ V  ++ A K    S 
Sbjct: 70  IDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSL 129

Query: 139 LPPADVSASIGSSPGVASNLTEPSYSSSTCGS 170
           L PA  S  I      A+    P +  S CGS
Sbjct: 130 LEPALASVVIHKE---ATVFDLPKF--SVCGS 156


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score =  244 bits (623), Expect = 2e-64
 Identities = 168/581 (28%), Positives = 273/581 (46%), Gaps = 53/581 (9%)

Query: 216 SSGLLQPPPPPPPPPALVPGYNGTS-----------NLSSYSYPS--------------- 249
           S G   P PP PPPP L P                 NL  +SYP                
Sbjct: 13  SGGASNPVPPRPPPPCLAPAPPAAGPAPPPESPHKRNLYYFSYPLFVGFALLRLVAFHLG 72

Query: 250 ------ASYPPQTAVGSGYSPGGAPPPPSAYLPSGIPAPTPLPPTTVPGYTYQGHGLTPI 303
                      +  + +  S G AP P SA  P+ +P         V  +  Q      I
Sbjct: 73  LLFVWLCQRFSRALMAAKRSSGAAPAPASASAPAPVPGGEA---ERVRVFHKQAFEYISI 129

Query: 304 APSALTNSSASSLKRKA-FYMAGQGDMDSSYGNYSYGQQRSTQSP---MYRMPDNSISNT 359
           A     +  A   ++   +Y  G  +++        GQ    +       +M  N +   
Sbjct: 130 ALRIDEDEKAGQKEQAVEWYKKGIEELEKGIAVIVTGQGEQCERARRLQAKMMTNLVMAK 189

Query: 360 NRGNGFDRSA---ETSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSS 416
           +R    +  A       L         S    +  S+  S     PSYS      G +  
Sbjct: 190 DRLQLLESGAVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQG 249

Query: 417 ESFGKYTSPVMSEHGDEHRQLLSHPMQGPGLRAATSSNHSVD-EQLKNTDTHLIDLVTNE 475
                 + P  + H    +   ++    P     T++    D +  +N D++L +L+ NE
Sbjct: 250 ------SGPAPTTHKGTPKTNRTNKPSTP----TTATRKKKDLKNFRNVDSNLANLIMNE 299

Query: 476 IITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLL 535
           I+  G  V ++DIAG DL K  ++E V+ P LR + F+GL A  R +LLFGP G GKT+L
Sbjct: 300 IVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTML 359

Query: 536 GRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQV 595
            + +A++  ATFF I+ + L +K++GE EK++ A F VAR  QPS+IF+ ++D LL  + 
Sbjct: 360 AKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERR 419

Query: 596 NEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDS 655
             EH    R++TEFL++ D V ++ +D+++V+ AT++P+E+DE++ R F+KR+ + LP+ 
Sbjct: 420 EGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNE 479

Query: 656 TARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSA 715
             R  ++  LL +    L  KE A L + T+G+SG D+  L ++A +GP+  +    +  
Sbjct: 480 ETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKN 539

Query: 716 IMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFG 756
           +  S++R +   DF  +  KI+ S+S + L+ Y+ WNK FG
Sbjct: 540 MSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFG 580


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score =  242 bits (617), Expect = 1e-63
 Identities = 116/298 (38%), Positives = 192/298 (64%)

Query: 459 EQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL 518
           +  +N D++L +L+ NEI+  G  V ++DIAG DL K  ++E V+ P LR + F+GL A 
Sbjct: 315 KNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAP 374

Query: 519 PRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQ 578
            R +LLFGP G GKT+L + +A++  ATFF I+ + L +K++GE EK++ A F VAR  Q
Sbjct: 375 ARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQ 434

Query: 579 PSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDE 638
           PS+IF+ ++D LL  +   EH    R++TEFL++ D V ++ +D+++V+ AT++P+E+DE
Sbjct: 435 PSIIFIDEVDSLLCERREGEHDASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDE 494

Query: 639 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ 698
           ++ R F+KR+ + LP+   R  ++  LL +    L  KE A L + T+G+SG D+  L +
Sbjct: 495 AVLRRFIKRVYVSLPNEETRLLLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAK 554

Query: 699 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFG 756
           +A +GP+  +    +  +  S++R +   DF  +  KI+ S+S + L+ Y+ WNK FG
Sbjct: 555 DAALGPIRELKPEQVKNMSASEMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFG 612


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  186 bits (473), Expect = 5e-47
 Identities = 121/387 (31%), Positives = 203/387 (52%), Gaps = 29/387 (7%)

Query: 393 SQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPM--QGPGLRAA 450
           S   R      YS  K S G+R S +   + S   + H D  + +       Q  G    
Sbjct: 109 SPGPRKRQSSQYSDPK-SHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEK 167

Query: 451 TSSNHSVDEQLKNT------DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLW 504
             S  +V E   N       D  L++ +  +II+Q P V W+DIA L   K ++KE V+ 
Sbjct: 168 NKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVL 227

Query: 505 PVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAE 564
           P+   + F G+    + +L+ GP GTGKTLL + +A++   TFF ++ S L +K+ GE+E
Sbjct: 228 PMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLTSKYRGESE 287

Query: 565 KIIHASFLVARCRQPSVIFVSDIDMLLSSQ-VNEEHSPVSRMRTEFLMQLDTVLTSAED- 622
           K++   F +AR   P+ IF+ +ID + S +  +EEH    R++ E L+Q+D V  ++E+ 
Sbjct: 288 KLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQMDGVGGTSEND 347

Query: 623 ----QIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEF 678
                ++V+ AT+ P +IDE+LRR   KR+ IPLP +  R +++ ++  +     +D + 
Sbjct: 348 DPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREELL-RISLRELELADDVDL 406

Query: 679 ALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLR---------PVTYQDF 729
           A + +  EG+SG D+ ++C++A    L AM    +  + P ++R         P T +DF
Sbjct: 407 ASIAENMEGYSGADITNVCRDA---SLMAM-RRRIEGLTPEEIRNLSKEEMHMPTTMEDF 462

Query: 730 ENAFCKIQPSISQKELDMYVEWNKMFG 756
           E A  K+  S+S  +++ Y +W   FG
Sbjct: 463 EMALKKVSKSVSAADIERYEKWIFEFG 489


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score =  180 bits (457), Expect = 4e-45
 Identities = 119/385 (30%), Positives = 200/385 (51%), Gaps = 54/385 (14%)

Query: 416 SESFGKYTSPVMSEHGDEHRQLLSHPMQGP----------GLRAATSS------NHSVDE 459
           S +FG + S +  + G+E+    +HP +G            ++ ATS       +H+ D 
Sbjct: 88  SANFGLHISRIRKDSGEEN----AHPRRGQIIDFQGLLTDAIKGATSELALNTFDHNPDP 143

Query: 460 Q------------LKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVL 507
                        + +    L  +V+ +I    P + WNDI GLD  K ++KE V++P+ 
Sbjct: 144 SERLLKPLSAFIGMNSEMRELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIR 203

Query: 508 RSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKII 567
               F+G+ +  + +LL+GP GTGKTLL + +A++   TFF I+ S +V+KW G++EK++
Sbjct: 204 YPQLFTGILSPWKGLLLYGPPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLV 263

Query: 568 HASFLVARCRQPSVIFVSDIDMLLSSQ---VNEEHSPVSRMRTEFLMQLDTVLTSAEDQI 624
              F +AR   PS IF+ +++ ++S +      EH    RM+TE L+Q+D  L  +ED +
Sbjct: 264 RVLFELARYHAPSTIFLDELESVMSQRGTASGGEHEGSLRMKTELLVQMDG-LARSEDLV 322

Query: 625 VVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLL-----SQHNYCLNDKEFA 679
            V+ A++ P E+D ++ R   KR+L+ LP   AR  +I   L     S+      + E++
Sbjct: 323 FVLAASNLPWELDCAMLRRLEKRILVDLPSREARQAMIYHWLPPVSKSRALELHTELEYS 382

Query: 680 LLVQRTEGFSGLDVAHLCQEAVVGPL---------HAMPATDLSAIMPSQLRPVTYQDFE 730
           +L Q TEG+SG D+  +C+EA + P+         H   ++DL  I   QL  VT  DF 
Sbjct: 383 VLSQETEGYSGSDIKLVCREAAMRPVRKIFDALENHQSESSDLPRI---QLDIVTTADFL 439

Query: 731 NAFCKIQPSISQKELDMYVEWNKMF 755
           +     +PS ++     Y +W + F
Sbjct: 440 DVLTHTKPS-AKNLAQRYSDWQREF 463


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  180 bits (457), Expect = 4e-45
 Identities = 99/303 (32%), Positives = 180/303 (59%), Gaps = 12/303 (3%)

Query: 465 DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILL 524
           D  L++ +  +I+++ P + W+DIA L+  K +++E V+ P+   D F G+    + +L+
Sbjct: 187 DKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLM 246

Query: 525 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFV 584
            GP GTGKT+L + +A++ G TFF ++ S L +K+ GE+EK++   F +AR   P+ IF+
Sbjct: 247 VGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFI 306

Query: 585 SDIDMLLSSQ-VNEEHSPVSRMRTEFLMQLDTVLTSAED-----QIVVICATSKPEEIDE 638
            +ID + S +  ++EH    R+++E L+Q+D V  + E+      ++V+ AT+ P +IDE
Sbjct: 307 DEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDE 366

Query: 639 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ 698
           +LRR   KR+ IPLP +  R +++   L +      D +   + ++ EG+SG D+ ++C+
Sbjct: 367 ALRRRLEKRIYIPLPTAKGRAELLKINLREVELD-PDIQLEDIAEKIEGYSGADITNVCR 425

Query: 699 EAVV----GPLHAMPATDLSAIMPSQLR-PVTYQDFENAFCKIQPSISQKELDMYVEWNK 753
           +A +      ++ +   ++ A+   +L+ PVT  DFE A  KI  S+S  +L+ Y +W  
Sbjct: 426 DASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKWMV 485

Query: 754 MFG 756
            FG
Sbjct: 486 EFG 488


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  180 bits (457), Expect = 4e-45
 Identities = 99/303 (32%), Positives = 180/303 (59%), Gaps = 12/303 (3%)

Query: 465 DTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILL 524
           D  L++ +  +I+++ P + W+DIA L+  K +++E V+ P+   D F G+    + +L+
Sbjct: 187 DKDLVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLM 246

Query: 525 FGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFV 584
            GP GTGKT+L + +A++ G TFF ++ S L +K+ GE+EK++   F +AR   P+ IF+
Sbjct: 247 VGPPGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFI 306

Query: 585 SDIDMLLSSQ-VNEEHSPVSRMRTEFLMQLDTVLTSAED-----QIVVICATSKPEEIDE 638
            +ID + S +  ++EH    R+++E L+Q+D V  + E+      ++V+ AT+ P +IDE
Sbjct: 307 DEIDSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDE 366

Query: 639 SLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ 698
           +LRR   KR+ IPLP +  R +++   L +      D +   + ++ EG+SG D+ ++C+
Sbjct: 367 ALRRRLEKRIYIPLPTAKGRAELLKINLREVELD-PDIQLEDIAEKIEGYSGADITNVCR 425

Query: 699 EAVV----GPLHAMPATDLSAIMPSQLR-PVTYQDFENAFCKIQPSISQKELDMYVEWNK 753
           +A +      ++ +   ++ A+   +L+ PVT  DFE A  KI  S+S  +L+ Y +W  
Sbjct: 426 DASLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKWMV 485

Query: 754 MFG 756
            FG
Sbjct: 486 EFG 488


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score =  169 bits (427), Expect = 1e-41
 Identities = 116/396 (29%), Positives = 198/396 (50%), Gaps = 45/396 (11%)

Query: 311 SSASSLKRKAFYMAGQGDMDSSYGNYSYGQQRSTQSPMYRMPDNSISNTNRGNGFDRSAE 370
           SS S   +KA  +A +   +   GNY    Q    +  Y +  + +    +G   D++ +
Sbjct: 2   SSTSPNLQKAIDLASKAAQEDKAGNYEEALQLYQHAVQYFL--HVVKYEAQG---DKAKQ 56

Query: 371 TSSLAFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEH 430
             S+  K T+ L  +E+ +++     +    P      +    + ++S G+       E 
Sbjct: 57  --SIRAKCTEYLDRAEKLKEYLKNKEKKAQKPVKEGQPSPADEKGNDSDGE------GES 108

Query: 431 GDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAG 490
            D  ++ L + +QG                               I+ + P V W+D+AG
Sbjct: 109 DDPEKKKLQNQLQGA------------------------------IVIERPNVKWSDVAG 138

Query: 491 LDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLG-ATFFK 549
           L+  K  +KE V+ P+     F+G     R ILLFGP GTGK+ L + +A++   +TFF 
Sbjct: 139 LEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNSTFFS 198

Query: 550 IAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRTEF 609
           I+ S LV+KWLGE+EK++   F +AR  +PS+IF+ +ID L  S+   E     R++TEF
Sbjct: 199 ISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENESEAARRIKTEF 258

Query: 610 LMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQH 669
           L+Q+  V     D I+V+ AT+ P  +D ++RR F KR+ IPLP+  AR  +    L   
Sbjct: 259 LVQMQGVGVD-NDGILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHLGTT 317

Query: 670 NYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPL 705
              L + +F  L ++T+G+SG D++ + ++A++ P+
Sbjct: 318 QNSLTEADFRELGRKTDGYSGADISIIVRDALMQPV 353


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score =  167 bits (422), Expect = 4e-41
 Identities = 91/251 (36%), Positives = 150/251 (59%), Gaps = 4/251 (1%)

Query: 476 IITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLL 535
           ++ + P + WND+AGL+  K  +KE V+ P+     F+G     R ILLFGP GTGK+ L
Sbjct: 117 VVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYL 176

Query: 536 GRCIASQLG-ATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQ 594
            + +A++   +TFF ++ S L++KWLGE+EK++   F +AR  +PS+IF+ ++D L  S+
Sbjct: 177 AKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSR 236

Query: 595 VNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPD 654
              E     R++TEFL+Q+  V  +  D  +V+ AT+ P  +D ++RR F KR+ IPLP+
Sbjct: 237 NENESEAARRIKTEFLVQMQGV-GNNNDGTLVLGATNIPWVLDSAIRRRFEKRIYIPLPE 295

Query: 655 STARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLH-AMPATDL 713
             AR Q+    L    + L D     L ++TEG+SG D++ + +++++ P+     AT  
Sbjct: 296 EAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPVRKVQSATHF 355

Query: 714 SAIM-PSQLRP 723
             +  PS+  P
Sbjct: 356 KKVCGPSRTNP 366


>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
          Length = 361

 Score =  145 bits (365), Expect = 2e-34
 Identities = 91/291 (31%), Positives = 151/291 (51%), Gaps = 15/291 (5%)

Query: 454 NHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF- 512
           N  + E   +   HL+D +          V W+DIAGLD V   +K+ V+ P+ +   F 
Sbjct: 66  NVKLSEYEMSIAAHLVDPLNMH-------VTWSDIAGLDDVITDLKDTVILPIKKKHLFE 118

Query: 513 -SGLTALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASF 571
            S L   P+ +LL+GP G GKTL+ +  A + G  F  +  S L  KW GE++K+  A F
Sbjct: 119 NSRLLQPPKGVLLYGPPGCGKTLIAKATAKEAGCRFINLQPSTLTDKWYGESQKLAAAVF 178

Query: 572 LVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATS 631
            +A   QPS+IF+ +ID  L ++ + +H   + M+ +F+   D + T    Q++V+ AT+
Sbjct: 179 SLAIKLQPSIIFIDEIDSFLRNRSSSDHEATAMMKAQFMSLWDGLDTDHSCQVIVMGATN 238

Query: 632 KPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALL--VQRTEGFS 689
           +P+++D ++ R    R  I  P    R  I+  +L   N    D+   LL   Q T+GFS
Sbjct: 239 RPQDLDSAIMRRMPTRFHINQPALKQREAILKLILKNENV---DRHVDLLEVAQETDGFS 295

Query: 690 GLDVAHLCQEAVVGPLHA-MPATDLSAIMPSQLRPVTYQDFENAFCKIQPS 739
           G D+  +C++A +  +   + +T   +    ++RPV  QD   A  K++ S
Sbjct: 296 GSDLKEMCRDAALLCVREYVNSTSEESHDEDEIRPVQQQDLHRAIEKMKKS 346


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  122 bits (305), Expect = 2e-27
 Identities = 85/283 (30%), Positives = 150/283 (53%), Gaps = 10/283 (3%)

Query: 483 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFS--GLTALPRSILLFGPRGTGKTLLGRCIA 540
           V ++ I GL      I+E +  P+ + + F   G+ A PR +LL+GP GTGKT++ R +A
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPA-PRGVLLYGPPGTGKTMIARAVA 408

Query: 541 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS 600
           +++GA    I G  +++K+ GE E  +   F  A  R PS+IF+ ++D L   +   ++ 
Sbjct: 409 NEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNE 468

Query: 601 PVSRMRTEFLMQLDTVLTS-AEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTA 657
              R+    L  +D + +  +E Q++V+ AT++P  +D +LRR   F K + I +P++  
Sbjct: 469 VEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQD 528

Query: 658 RHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAM--PATDLSA 715
           R  I+ +LL +  + L + E   L     G+ G D+  LC EA +  L  +     +L  
Sbjct: 529 RLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPNLPD 588

Query: 716 IMPSQLRPVTYQDFENAFCKIQPSISQK-ELDM-YVEWNKMFG 756
           +  + L  +T +DF  A   I+PS  ++  +D+  V W+ + G
Sbjct: 589 VKVAGLVKITLKDFLQAMNDIRPSAMREIAIDVPNVSWSDIGG 631



 Score =  120 bits (300), Expect = 6e-27
 Identities = 75/287 (26%), Positives = 146/287 (50%), Gaps = 18/287 (6%)

Query: 475 EIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKT 533
           EI    P V W+DI GL+ +K  +++ V WP+   ++F  +   P + +LL+GP G  KT
Sbjct: 616 EIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKT 675

Query: 534 LLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSS 593
           ++ + +A++ G  F  I G  L+ K++GE+E+ +  +F  AR   PS+IF  ++D L   
Sbjct: 676 MIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVE 735

Query: 594 QVNE--EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLL 649
           + +     +   R+  + L ++D +       + ++ AT++P+ ID++L R     + + 
Sbjct: 736 RGSSLGAGNVADRVLAQLLTEMDGI--EQLKDVTILAATNRPDRIDKALMRPGRIDRIIY 793

Query: 650 IPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMP 709
           +PLPD+  R +I  +L        N+ +   L+ +T+ +SG ++  +C+EA +  L    
Sbjct: 794 VPLPDAATRREIF-KLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALE--- 849

Query: 710 ATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFG 756
             D+ A +      +  + F  A   + P I +     Y ++ +  G
Sbjct: 850 -EDIQANL------IMKRHFTQALSTVTPRIPESLRRFYEDYQEKSG 889


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  119 bits (298), Expect = 1e-26
 Identities = 85/267 (31%), Positives = 138/267 (51%), Gaps = 15/267 (5%)

Query: 483 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIAS 541
           V ++DI G     A IKE V  P+     F  +   P R ILL+GP GTGKTL+ R +A+
Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260

Query: 542 QLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSP 601
           + GA FF I G  +++K  GE+E  +  +F  A    P++IF+ ++D +   +       
Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEV 320

Query: 602 VSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRY--FMKRLLIPLPDSTARH 659
             R+ ++ L  +D +   A   ++V+ AT++P  ID +LRR+  F + + I +PD+T R 
Sbjct: 321 ERRIVSQLLTLMDGLKQRA--HVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRL 378

Query: 660 QIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLH-AMPATDL----- 713
           +I+ Q+ +++    +D +   +   T G  G D+A LC EA +  +   M   DL     
Sbjct: 379 EIL-QIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETI 437

Query: 714 -SAIMPSQLRPVTYQDFENAFCKIQPS 739
            + +M S    VT  DF  A  +  PS
Sbjct: 438 DAEVMNS--LAVTMDDFRWALSQSNPS 462



 Score =  119 bits (297), Expect = 1e-26
 Identities = 74/232 (31%), Positives = 120/232 (51%), Gaps = 9/232 (3%)

Query: 475 EIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKT 533
           E + + P V W DI GL+ VK  ++E V +PV   D F      P + +L +GP G GKT
Sbjct: 466 ETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKT 525

Query: 534 LLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSS 593
           LL + IA++  A F  I G  L+  W GE+E  +   F  AR   P V+F  ++D +  +
Sbjct: 526 LLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKA 585

Query: 594 Q---VNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRL 648
           +   + +      R+  + L ++D +  S +  + +I AT++P+ ID ++ R     + +
Sbjct: 586 RGGNIGDGGGAADRVINQILTEMDGM--STKKNVFIIGATNRPDIIDPAILRPGRLDQLI 643

Query: 649 LIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEA 700
            IPLPD  +R  I+   L + +    D +   L + T GFSG D+  +CQ A
Sbjct: 644 YIPLPDEKSRVAILKANL-RKSPVAKDVDLEFLAKMTNGFSGADLTEICQRA 694


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  118 bits (296), Expect = 2e-26
 Identities = 94/309 (30%), Positives = 153/309 (49%), Gaps = 24/309 (7%)

Query: 449 AATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLR 508
           A  + ++++ + L N    L+ L+  E +   P   +  I GLD     IKE +  PV  
Sbjct: 115 ALRNDSYTLHKILPNKVDPLVSLMMVEKV---PDSTYEMIGGLDKQIKEIKEVIELPVKH 171

Query: 509 SDAFSGL-TALPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKII 567
            + F  L  A P+ +LL+GP GTGKTLL R +A     TF +++GS LV K++GE  +++
Sbjct: 172 PELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMV 231

Query: 568 HASFLVARCRQPSVIFVSDIDMLLSSQV---NEEHSPVSRMRTEFLMQLDTVLTSAEDQI 624
              F++AR   PS+IF+ +ID + SS++   +   S V R   E L QLD     A   I
Sbjct: 232 RELFVMAREHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGF--EATKNI 289

Query: 625 VVICATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLV 682
            VI AT++ + +D +L R     +++  P P+  AR  I+ ++ S+            + 
Sbjct: 290 KVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDIL-KIHSRKMNLTRGINLRKIA 348

Query: 683 QRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQ 742
           +   G SG +V  +C EA            + A+   ++  VT +DFE A  K+    S+
Sbjct: 349 ELMPGASGAEVKGVCTEA-----------GMYALRERRVH-VTQEDFEMAVAKVMQKDSE 396

Query: 743 KELDMYVEW 751
           K + +   W
Sbjct: 397 KNMSIKKLW 405


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  116 bits (290), Expect = 9e-26
 Identities = 88/324 (27%), Positives = 150/324 (46%), Gaps = 15/324 (4%)

Query: 383 MSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGDEHRQLLSHPM 442
           +  +Q+ + S       TP S  T +  +     ++    ++ V SEH       +   +
Sbjct: 88  LEEKQEEERSKVDDLRGTPMSVGTLEEII----DDNHAIVSTSVGSEHYVSILSFVDKDL 143

Query: 443 QGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEV 502
             PG   +   NH V   +         LVT   + + P   + DI GLD     IKE V
Sbjct: 144 LEPG--CSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESV 201

Query: 503 LWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLG 561
             P+   + +  +   P + ++L+GP GTGKTLL + +A+Q  ATF ++ GS L+ K+LG
Sbjct: 202 ELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLG 261

Query: 562 EAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEE---HSPVSRMRTEFLMQLDTVLT 618
           +  K++   F VA    PS++F+ +ID + + + +        + R   E L QLD    
Sbjct: 262 DGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGF-- 319

Query: 619 SAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDK 676
            +   + VI AT++ E +D +L R     +++  PLPD   + +I  Q+ +      +D 
Sbjct: 320 DSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIF-QIHTSRMTLADDV 378

Query: 677 EFALLVQRTEGFSGLDVAHLCQEA 700
               L+   +  SG D+  +C EA
Sbjct: 379 TLDDLIMAKDDLSGADIKAICTEA 402


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  115 bits (288), Expect = 2e-25
 Identities = 81/275 (29%), Positives = 137/275 (49%), Gaps = 10/275 (3%)

Query: 481 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL-PRSILLFGPRGTGKTLLGRCI 539
           P V W DI  L+ ++  +   +L PV   D F  L  + P  +LL GP G GKTLL + +
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 540 ASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEH 599
           A++ G  F  + G  L+  ++GE+E+ +   F  A+   P VIF  ++D L   + + E 
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 600 SPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTA 657
               R+  + L ++D +   A  Q+ ++ AT++P+ ID ++ R     K L + LP    
Sbjct: 590 GASVRVVNQLLTEMDGL--EARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 647

Query: 658 RHQIIVQLLSQHNYCLNDKEFALLV----QRTEGFSGLDVAHLCQEAVVGPLHAMPATDL 713
           R  I+  +         D +  L       R + ++G D++ L +EA +  L    A   
Sbjct: 648 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQK 707

Query: 714 SAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMY 748
           S     +L+ V+++ FE AF K++ SIS+K+  MY
Sbjct: 708 SGNEKGELK-VSHKHFEEAFKKVRSSISKKDQIMY 741



 Score = 92.4 bits (228), Expect = 1e-18
 Identities = 68/225 (30%), Positives = 115/225 (51%), Gaps = 8/225 (3%)

Query: 483 VDWNDIAGLDL-VKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIA 540
           V + D+ G D+ +K V K  +L  +   + +  L  +P R +LL GP G GKTLL   IA
Sbjct: 156 VKFEDVGGNDMTLKEVCK--MLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIA 213

Query: 541 SQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS 600
            +L     K+A   +V+   GE+E+ +   F  A    P +IF+ +ID +   +      
Sbjct: 214 GELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKD 273

Query: 601 PVSRMRTEFLMQLDTV-LTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTA 657
              R+  + L  +D +   +A  +++VI AT++P+ +D +LRR   F + + + +PD  +
Sbjct: 274 MERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEAS 333

Query: 658 RHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVV 702
           R +I+ Q L +        +F  L   T GF G D+  LC+EA +
Sbjct: 334 RERIL-QTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAM 377


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  115 bits (288), Expect = 2e-25
 Identities = 81/275 (29%), Positives = 137/275 (49%), Gaps = 10/275 (3%)

Query: 481 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTAL-PRSILLFGPRGTGKTLLGRCI 539
           P V W DI  L+ ++  +   +L PV   D F  L  + P  +LL GP G GKTLL + +
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 540 ASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEH 599
           A++ G  F  + G  L+  ++GE+E+ +   F  A+   P VIF  ++D L   + + E 
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 600 SPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTA 657
               R+  + L ++D +   A  Q+ ++ AT++P+ ID ++ R     K L + LP    
Sbjct: 696 GASVRVVNQLLTEMDGL--EARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 753

Query: 658 RHQIIVQLLSQHNYCLNDKEFALLV----QRTEGFSGLDVAHLCQEAVVGPLHAMPATDL 713
           R  I+  +         D +  L       R + ++G D++ L +EA +  L    A   
Sbjct: 754 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQK 813

Query: 714 SAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMY 748
           S     +L+ V+++ FE AF K++ SIS+K+  MY
Sbjct: 814 SGNEKGELK-VSHKHFEEAFKKVRSSISKKDQIMY 847



 Score = 95.5 bits (236), Expect = 2e-19
 Identities = 102/400 (25%), Positives = 174/400 (43%), Gaps = 31/400 (7%)

Query: 322 YMAGQGDMDSSYGNY----SYGQQRSTQSPMYRMPD-NSISNTNRGNGFDRSAETSSLAF 376
           Y     D DSS  +Y    S     S+   +YR  + +S+SNT      + ++ T  ++ 
Sbjct: 96  YTESYSDDDSSMEDYPDPQSANHMNSSLLSLYRKGNPDSVSNTPEMEQRETTSSTPRISS 155

Query: 377 K----PTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLGSRSSESFGKYTSPVMSEHGD 432
           K    P K      +   F  +     TP   S  K+S     S        P+      
Sbjct: 156 KTGSIPLKTPAKDSEGGWFIDK-----TP---SVKKDSFFLDLSCEKSNPKKPITEIQDS 207

Query: 433 EHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQG-----PPVDWND 487
           +   LL   M+  G +     +    E L+  D  +  ++  +   +G       V + D
Sbjct: 208 KDSSLLESDMKRKG-KLKNKGSKRKKEDLQEVDGEIEAVLQKKAKARGLEFQISNVKFED 266

Query: 488 IAGLDL-VKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIASQLGA 545
           + G D+ +K V K  +L  +   + +  L  +P R +LL GP G GKTLL   IA +L  
Sbjct: 267 VGGNDMTLKEVCK--MLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGELDL 324

Query: 546 TFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRM 605
              K+A   +V+   GE+E+ +   F  A    P +IF+ +ID +   +         R+
Sbjct: 325 PILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMERRI 384

Query: 606 RTEFLMQLDTV-LTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQII 662
             + L  +D +   +A  +++VI AT++P+ +D +LRR   F + + + +PD  +R +I+
Sbjct: 385 VAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERIL 444

Query: 663 VQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVV 702
            Q L +        +F  L   T GF G D+  LC+EA +
Sbjct: 445 -QTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAM 483


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  113 bits (282), Expect = 7e-25
 Identities = 72/230 (31%), Positives = 125/230 (54%), Gaps = 9/230 (3%)

Query: 477 ITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLL 535
           + + P   ++DI GLD     + E ++ P+   + F  L   P + +L++GP GTGKTLL
Sbjct: 177 VDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLL 236

Query: 536 GRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQV 595
            R  A+Q  ATF K+AG  LV  ++G+  K++  +F +A+ + PS+IF+ ++D + + + 
Sbjct: 237 ARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRF 296

Query: 596 NEEHS---PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLI 650
           + E +    V R   E L QLD        Q+ VI AT++ + +D +L R     +++  
Sbjct: 297 DSEKAGDREVQRTMLELLNQLDGF--QPNTQVKVIAATNRVDILDPALLRSGRLDRKIEF 354

Query: 651 PLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEA 700
           P+P+  AR + I+Q+ S+      D  +  L + T+ F+G     +C EA
Sbjct: 355 PMPNEEARAR-IMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEA 403


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  110 bits (274), Expect = 6e-24
 Identities = 71/227 (31%), Positives = 126/227 (55%), Gaps = 15/227 (6%)

Query: 483 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIAS 541
           V +++I GL      ++E +  P+   + F  +  +P +  LL+GP GTGKTLL R +AS
Sbjct: 144 VSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVAS 203

Query: 542 QLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHS- 600
           QL   F K+  S +V K++GE+ ++I   F  AR  QP +IF+ +ID +   + +E  S 
Sbjct: 204 QLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSA 263

Query: 601 --PVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDST 656
              + R   E L Q+D   T    ++ +I AT++P+ +D +L R     +++ I LP+  
Sbjct: 264 DREIQRTLMELLNQMDGFDTL--HRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQ 321

Query: 657 ARHQII---VQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEA 700
           AR  I+      +++H     + ++  +V+ ++GF+G D+ ++C EA
Sbjct: 322 ARLDILKIHAGPITKH----GEIDYEAIVKLSDGFNGADLRNVCTEA 364


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  108 bits (270), Expect = 2e-23
 Identities = 88/300 (29%), Positives = 148/300 (49%), Gaps = 34/300 (11%)

Query: 482 PVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF--SGLTALPRSILLFGPRGTGKTLLGRCI 539
           PVDW +I GL+ VK  +K+ + WP+     F   GLT  P+ +LL+GP G  KT L R +
Sbjct: 460 PVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQ-PKGVLLYGPPGCAKTTLVRAL 518

Query: 540 ASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEH 599
           A+    +F  ++G+ L + ++G++EK++   F  AR   P+++F+ +ID +L ++   + 
Sbjct: 519 ATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKT 578

Query: 600 --SPVSRMRTEFLMQLDTV-LTSAEDQ----------------IVVICATSKPEEIDESL 640
                 R+ +  L +LD V L + E +                +++I AT++P+ +D +L
Sbjct: 579 GCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTAL 638

Query: 641 RR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQ 698
            R     K + IP PD   R  I+ ++ ++      D     L   T  FSG D+ +LC 
Sbjct: 639 LRPGRLDKIIYIPPPDHKGRLSIL-KVCTKTMPIGPDVSLENLAAETCFFSGADLRNLCT 697

Query: 699 EAVVGPLHAMPATDLSAIMPSQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMFGCS 758
           EA    L A+    L A    Q      + F  +   ++PS+S K+L +Y    K  G S
Sbjct: 698 EAA---LLALQENGLDATTVKQ------EHFLKSLKTVKPSLSCKDLALYENLFKKEGFS 748



 Score =  100 bits (248), Expect = 7e-21
 Identities = 83/280 (29%), Positives = 141/280 (50%), Gaps = 24/280 (8%)

Query: 488 IAGLDLVKAVIKEEVLWPVLRSDAFSGL-TALPRSILLFGPRGTGKTLLGRCIASQLGAT 546
           + GL      ++E +  P+    A + L  A+PR +LL GP G GKT L R +A + GA 
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261

Query: 547 FFKIAGSGLVAKWLGEAEKIIHASFLVAR---CRQPSVIFVSDIDMLLSSQVNEEHSPVS 603
              ++   L     GE E+ +   F  AR    R PS++F+ ++D L   +     +P S
Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR--GSRAPES 319

Query: 604 RMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQI 661
           R+  + L  LD    S + ++VV+ AT++P+ +D +LRR   F + ++I  P    R +I
Sbjct: 320 RVVAQVLTLLDG--ASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEI 377

Query: 662 IVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQL 721
           + Q+++      +  +  LL + T G+ G D+  LC+EA    +HA+  ++      +Q 
Sbjct: 378 L-QVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAA---MHALLHSE-----KNQD 428

Query: 722 RPVTYQ-DFENAFCKIQPSISQKELDMY----VEWNKMFG 756
            PV  + DF  AF  IQPS  +  + +     V+W ++ G
Sbjct: 429 NPVIDEIDFLEAFKNIQPSSFRSVIGLMDIKPVDWEEIGG 468


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  108 bits (269), Expect = 2e-23
 Identities = 72/254 (28%), Positives = 129/254 (50%), Gaps = 13/254 (5%)

Query: 453 SNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF 512
           SN  VD      D+ ++ L ++    Q P V + DI G+D+ K  ++E V  P+   + +
Sbjct: 132 SNALVDVLPPEADSSIMMLTSD----QKPDVMYADIGGMDIQKQEVREAVELPLTHFELY 187

Query: 513 SGLTA-LPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASF 571
             +    PR +L++GP G GKT+L + +A    A F ++ GS  V K+LGE  +++   F
Sbjct: 188 KQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVF 247

Query: 572 LVARCRQPSVIFVSDIDMLLSSQVNEE---HSPVSRMRTEFLMQLDTVLTSAEDQIVVIC 628
            +A+   P++IF+ +ID + + + + +      V R+  E L Q+D         + VI 
Sbjct: 248 RLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGF--DQNVNVKVIM 305

Query: 629 ATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTE 686
           AT++ + +D +L R     +++  PLPD   +  I   + S+ N    + +    V R +
Sbjct: 306 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLS-EEVDLEDYVARPD 364

Query: 687 GFSGLDVAHLCQEA 700
             SG D+  +CQE+
Sbjct: 365 KISGADINSICQES 378


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  108 bits (269), Expect = 2e-23
 Identities = 72/254 (28%), Positives = 129/254 (50%), Gaps = 13/254 (5%)

Query: 453 SNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF 512
           SN  VD      D+ ++ L ++    Q P V + DI G+D+ K  ++E V  P+   + +
Sbjct: 105 SNALVDVLPPEADSSIMMLTSD----QKPDVMYADIGGMDIQKQEVREAVELPLTHFELY 160

Query: 513 SGLTA-LPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASF 571
             +    PR +L++GP G GKT+L + +A    A F ++ GS  V K+LGE  +++   F
Sbjct: 161 KQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVF 220

Query: 572 LVARCRQPSVIFVSDIDMLLSSQVNEE---HSPVSRMRTEFLMQLDTVLTSAEDQIVVIC 628
            +A+   P++IF+ +ID + + + + +      V R+  E L Q+D         + VI 
Sbjct: 221 RLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGF--DQNVNVKVIM 278

Query: 629 ATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTE 686
           AT++ + +D +L R     +++  PLPD   +  I   + S+ N    + +    V R +
Sbjct: 279 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLS-EEVDLEDYVARPD 337

Query: 687 GFSGLDVAHLCQEA 700
             SG D+  +CQE+
Sbjct: 338 KISGADINSICQES 351


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  108 bits (269), Expect = 2e-23
 Identities = 72/254 (28%), Positives = 129/254 (50%), Gaps = 13/254 (5%)

Query: 453 SNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAF 512
           SN  VD      D+ ++ L ++    Q P V + DI G+D+ K  ++E V  P+   + +
Sbjct: 136 SNALVDVLPPEADSSIMMLTSD----QKPDVMYADIGGMDIQKQEVREAVELPLTHFELY 191

Query: 513 SGLTA-LPRSILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASF 571
             +    PR +L++GP G GKT+L + +A    A F ++ GS  V K+LGE  +++   F
Sbjct: 192 KQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVF 251

Query: 572 LVARCRQPSVIFVSDIDMLLSSQVNEE---HSPVSRMRTEFLMQLDTVLTSAEDQIVVIC 628
            +A+   P++IF+ +ID + + + + +      V R+  E L Q+D         + VI 
Sbjct: 252 RLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGF--DQNVNVKVIM 309

Query: 629 ATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTE 686
           AT++ + +D +L R     +++  PLPD   +  I   + S+ N    + +    V R +
Sbjct: 310 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLS-EEVDLEDYVARPD 368

Query: 687 GFSGLDVAHLCQEA 700
             SG D+  +CQE+
Sbjct: 369 KISGADINSICQES 382


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  104 bits (260), Expect = 3e-22
 Identities = 76/231 (32%), Positives = 116/231 (50%), Gaps = 16/231 (6%)

Query: 483 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIAS 541
           V ++ I GL      +KE V++P+L  + F      P R  L +GP GTGKTL+ R +A+
Sbjct: 397 VRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALAN 456

Query: 542 QLG-----ATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLL---SS 593
           +         FF   G+  ++KW+GE+E+ +   F  A   +PS+IF  +ID L    SS
Sbjct: 457 ECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSS 516

Query: 594 QVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIP 651
           + ++ HS +       +  LD        +IVVI AT++ + ID +LRR   F +  L  
Sbjct: 517 RQDQIHSSIVSTLLALMDGLDN-----RGEIVVIGATNRLDSIDPALRRPGRFDREFLFN 571

Query: 652 LPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVV 702
           LPD  AR  I+       N  L+D     L ++  G+ G D+  LC EA +
Sbjct: 572 LPDQKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAAL 622


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  102 bits (255), Expect = 1e-21
 Identities = 83/272 (30%), Positives = 131/272 (48%), Gaps = 20/272 (7%)

Query: 483 VDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALP-RSILLFGPRGTGKTLLGRCIAS 541
           V ++ + GL    A +KE V++P+L  + F      P R  L +GP GTGKTL+ R +A+
Sbjct: 423 VRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALAN 482

Query: 542 QLG-----ATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLL---SS 593
           +         FF   G+  ++KW+GE+E+ +   F  A   +PS+IF  +ID L    SS
Sbjct: 483 ECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSS 542

Query: 594 QVNEEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIP 651
           + ++ HS +       +  LD     +  +IVVI AT++ + ID +LRR   F +  L  
Sbjct: 543 RQDQIHSSIVSTLLALMDGLD-----SRGEIVVIGATNRLDSIDPALRRPGRFDREFLFS 597

Query: 652 LPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPAT 711
           LPD  AR +I+       N    D     L +   G+ G D+  +C EA +  L      
Sbjct: 598 LPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYCGADIKSICAEAALCALRRRYPQ 657

Query: 712 DLSAIMPSQLR----PVTYQDFENAFCKIQPS 739
             +     QL      ++ +DFE A  K+ P+
Sbjct: 658 IYTTSEKLQLDLSSINISAKDFEVAMQKMIPA 689


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  101 bits (251), Expect = 3e-21
 Identities = 66/227 (29%), Positives = 115/227 (50%), Gaps = 6/227 (2%)

Query: 485  WNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRS-ILLFGPRGTGKTLLGRCIASQL 543
            W+ I GL  V+ ++ + +  P    + F+ L    R+ ILL+GP GTGKTLL   IA + 
Sbjct: 839  WDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARES 898

Query: 544  GATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVS 603
               F  + G  L++K++G +E+ +   F+ A+  +P ++F  + + +   + ++      
Sbjct: 899  RMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTD 958

Query: 604  RMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDSTARHQI 661
            R+  + L QLD V       + V+ ATS+P+ ID +L R     K +  P PD  +R +I
Sbjct: 959  RVVNQLLTQLDGV--EGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEI 1016

Query: 662  IVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAM 708
            +  +LS      +D +   +   T+ F+G D+  L   A +  LH M
Sbjct: 1017 L-NVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGM 1062



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 69/339 (20%), Positives = 135/339 (39%), Gaps = 41/339 (12%)

Query: 445 PGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLW 504
           P L   T+    +D  +K  ++  ID +        P +  + + G++ +     E +  
Sbjct: 520 PNLLQKTTIQVLLDPMVKEENSEEIDFIL-------PFLKLSSLGGVNSLGVSSLEHITH 572

Query: 505 PVLRSDAFSGLTALPR-----SILLFGPRGTGKTLLGRCIASQ----LGATFFKIAGSGL 555
            +L       L +L       ++LL G +G+GK+ L + I  +    L A   ++    L
Sbjct: 573 SLLGRPLSRQLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKAL 632

Query: 556 VAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDML--LSSQVNEEHSPVSRMRTEFLMQL 613
             K L   +K +  +F  A   QPSV+ + D+D++  L +    EHSP +         L
Sbjct: 633 RGKRLENIQKTLEVAFSEAVWMQPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQRLAHAL 692

Query: 614 DTVLTS--AEDQIVVICATSKPEE------IDESLRRYFMKRLLIPLPDSTARHQIIVQL 665
           + ++    +   +V + ATS+ ++      +       F     I  P+   R +I+  +
Sbjct: 693 NDMIKEFISMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNV 752

Query: 666 LSQHNYC----LNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQL 721
           +     C      D +   + + T GF   D   L   A+   L         +I   + 
Sbjct: 753 IKNKLDCDINKFTDLDLQHVAKETGGFVARDFTVLVDRAIHSRL------SRQSISTREK 806

Query: 722 RPVTYQDFENAFCKIQPSISQKELDMY----VEWNKMFG 756
             +T  DF+ A     P+ S + ++++    + W+K+ G
Sbjct: 807 LVLTTLDFQKALRGFLPA-SLRSVNLHKPRDLGWDKIGG 844


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  100 bits (249), Expect = 5e-21
 Identities = 81/283 (28%), Positives = 139/283 (49%), Gaps = 13/283 (4%)

Query: 481 PPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRS-ILLFGPRGTGKTLLGRCI 539
           P V W+D+ GL  VK  I E +  P+   +  S    L RS +LL GP GTGKTLL + +
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS--LGLRRSGLLLHGPPGTGKTLLAKAV 757

Query: 540 ASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSS--QVNE 597
           A++   TF  + G  L+  ++G++E+ +   F  AR   P +IF  ++D L  S  +  +
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 817

Query: 598 EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFMKRLLIPLPDS 655
               + R+ ++ L +LD  L S +D + VI AT++P+ +D +L R   F K + +   + 
Sbjct: 818 SGGVMDRVVSQLLAELDG-LHSTQD-VFVIGATNRPDLLDPALLRPGRFDKLVFVGANED 875

Query: 656 TARHQIIVQLLSQHNYCLNDKEFALLVQR--TEGFSGLDVAHLCQEAVVGPLHAMPATDL 713
            A    ++  +++  + L      + V        +G D+  LC +A+   L        
Sbjct: 876 RASQLRVLSAITR-KFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRRVHDLE 934

Query: 714 SAIMP-SQLRPVTYQDFENAFCKIQPSISQKELDMYVEWNKMF 755
             + P S    +T +D   A  ++QPS+S++EL  Y    + F
Sbjct: 935 EGLEPGSSALMLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 977



 Score = 54.7 bits (130), Expect = 3e-07
 Identities = 50/189 (26%), Positives = 87/189 (46%), Gaps = 16/189 (8%)

Query: 521 SILLFGPRGTGKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPS 580
           S+LL GP G GKT +     S LG    K+  S L A+  G  E  + A F  AR  +P+
Sbjct: 465 SVLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPA 524

Query: 581 VIFVSDIDMLLSSQVN-EEHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDES 639
           V+ ++ +D+L   +    E + V  +    L+  D +  ++   ++V+  TS+ +++   
Sbjct: 525 VLLLTAVDLLGRDRDGLGEDARVMAVLRHLLLNEDPL--NSCPPLMVVATTSRAQDLPAD 582

Query: 640 LRRYFMKRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQE 699
           ++  F   L +P   S  +   I++ L+ H     +   A L +R  GF           
Sbjct: 583 VQTAFPHELEVPAL-SEGQRLSILRALTAHLPLGQEVNLAQLARRCAGF----------- 630

Query: 700 AVVGPLHAM 708
            VVG L+A+
Sbjct: 631 -VVGDLYAL 638


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  100 bits (249), Expect = 5e-21
 Identities = 69/235 (29%), Positives = 120/235 (51%), Gaps = 9/235 (3%)

Query: 472 VTNEIITQGPPVDWNDIAGLDLVKAVIKEEVLWPVLRSDAFSGL-TALPRSILLFGPRGT 530
           VT   + + P V ++D+ G       ++E V  P+L  + F  L    P+ +LLFGP GT
Sbjct: 161 VTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGT 220

Query: 531 GKTLLGRCIASQLGATFFKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDML 590
           GKTL  R +A++  A F ++ GS LV K++GE  +++   F +AR ++  +IF  +ID +
Sbjct: 221 GKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAI 280

Query: 591 LSSQVNE---EHSPVSRMRTEFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRR--YFM 645
             ++ ++     + V R   E + QLD         I V+ AT++P+ +D +L R     
Sbjct: 281 GGARFDDGAGGDNEVQRTMLELINQLDGF--DPRGNIKVLMATNRPDTLDPALMRPGRLD 338

Query: 646 KRLLIPLPDSTARHQIIVQLLSQHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEA 700
           +++   LPD   R  I  ++ ++      D  F LL +     +G ++  +C EA
Sbjct: 339 RKIEFSLPDLEGRTHIF-KIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.383 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,577,754
Number of Sequences: 37866
Number of extensions: 2102366
Number of successful extensions: 29621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 495
Number of HSP's successfully gapped in prelim test: 1421
Number of HSP's that attempted gapping in prelim test: 12621
Number of HSP's gapped (non-prelim): 8420
length of query: 759
length of database: 18,247,518
effective HSP length: 110
effective length of query: 649
effective length of database: 14,082,258
effective search space: 9139385442
effective search space used: 9139385442
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.