BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126352700 elastin isoform b precursor [Homo sapiens] (677 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126352700 elastin isoform b precursor [Homo sapiens] 1356 0.0 gi|126352322 elastin isoform c precursor [Homo sapiens] 1342 0.0 gi|126352608 elastin isoform e precursor [Homo sapiens] 1337 0.0 gi|126352446 elastin isoform d precursor [Homo sapiens] 1330 0.0 gi|126352440 elastin isoform a precursor [Homo sapiens] 1325 0.0 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 181 2e-45 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 170 5e-42 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 169 6e-42 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 160 4e-39 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 160 4e-39 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 160 4e-39 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 160 4e-39 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 157 2e-38 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 157 2e-38 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 152 1e-36 gi|48762934 alpha 2 type I collagen [Homo sapiens] 152 1e-36 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 150 3e-36 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 149 1e-35 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 149 1e-35 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 147 2e-35 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 147 2e-35 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 144 3e-34 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 143 5e-34 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 139 7e-33 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 139 7e-33 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 139 7e-33 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 139 7e-33 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 139 7e-33 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 139 9e-33 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 138 1e-32 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 1356 bits (3510), Expect = 0.0 Identities = 677/677 (100%), Positives = 677/677 (100%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL 60 Query: 61 AGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP 120 AGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP Sbjct: 61 AGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP 120 Query: 121 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP 180 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP Sbjct: 121 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP 180 Query: 181 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 240 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV Sbjct: 181 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 240 Query: 241 GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAA 300 GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAA Sbjct: 241 GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAA 300 Query: 301 AKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSP 360 AKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSP Sbjct: 301 AKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSP 360 Query: 361 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVG 420 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVG Sbjct: 361 EAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVG 420 Query: 421 GVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 480 GVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV Sbjct: 421 GVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 480 Query: 481 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP 540 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP Sbjct: 481 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVP 540 Query: 541 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 600 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA Sbjct: 541 GLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAA 600 Query: 601 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP 660 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP Sbjct: 601 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSP 660 Query: 661 IFPGGACLGKACGRKRK 677 IFPGGACLGKACGRKRK Sbjct: 661 IFPGGACLGKACGRKRK 677 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 1342 bits (3473), Expect = 0.0 Identities = 677/692 (97%), Positives = 677/692 (97%), Gaps = 15/692 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 111 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 165 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 166 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 225 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 226 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 285 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 286 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 345 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 346 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 405 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 465 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 Query: 466 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG Sbjct: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 Query: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI Sbjct: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 Query: 586 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 645 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA Sbjct: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 Query: 646 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 677 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 1337 bits (3460), Expect = 0.0 Identities = 677/705 (96%), Positives = 677/705 (96%), Gaps = 28/705 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 111 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 170 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 171 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 230 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 231 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 290 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 410 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 411 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 470 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 480 Query: 471 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 530 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV Sbjct: 481 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 540 Query: 531 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 590 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV Sbjct: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 600 Query: 591 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY-- 648 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY Sbjct: 601 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA 660 Query: 649 ----------------GVAARPGFGLSPIFPGGACLGKACGRKRK 677 GVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 1330 bits (3443), Expect = 0.0 Identities = 677/711 (95%), Positives = 677/711 (95%), Gaps = 34/711 (4%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 111 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 165 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 166 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 225 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 226 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 285 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 286 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 345 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 346 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 405 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 446 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 Query: 447 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 506 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 Query: 507 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 566 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 Query: 567 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 626 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 Query: 627 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 677 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 1325 bits (3430), Expect = 0.0 Identities = 677/724 (93%), Positives = 677/724 (93%), Gaps = 47/724 (6%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 111 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 170 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 171 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 230 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 231 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 290 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 410 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 411 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVPGVGVA 451 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVPGVGVA Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 Query: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 511 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL Sbjct: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 Query: 512 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 571 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP Sbjct: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 Query: 572 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 631 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV Sbjct: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 Query: 632 GGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACLGKACG 673 GGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACLGKACG Sbjct: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 Query: 674 RKRK 677 RKRK Sbjct: 721 RKRK 724 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 181 bits (459), Expect = 2e-45 Identities = 238/715 (33%), Positives = 266/715 (37%), Gaps = 95/715 (13%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPAL-GPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPG 79 P+ P G PG+ PG G PG + L G G+P P P G G G P T P Sbjct: 282 PAGPKGEPGS-PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA 340 Query: 80 AL--VPGGV-ADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVKPGKVPGV 134 PG V A A + + G GV G G AGA P PGA +PG Sbjct: 341 GPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400 Query: 135 GLPGVYPGGVLPGARFP----GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 190 G PG+ PGAR P G G PG P G +P APG G GP G P Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPG-PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGP 459 Query: 191 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV----GPQAAA 246 P G K G G P TG LP GP G G G G+P GV GP Sbjct: 460 PGPAGEEGKR----GARGEPGPTG-LP---GPPGERGGPGSRGFPGADGVAGPKGPAGER 511 Query: 247 AAAAKAAAKFGAGAAGV-----LPGVGG-AGVPGVPG--------------------AIP 280 + A K G AG LPG G G PG PG P Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571 Query: 281 GIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-FGP-GVVGVPGA-GVPGVGV 336 G G AGV G P AA KA + G VPG PG GP G G GA G PG Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERG-----VPGPPGAVGPAGKDGEAGAQGPPGPAG 626 Query: 337 PGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 396 P AG PG G+ P A K + G +G G P+ G GFPG Sbjct: 627 PAGERGEQGPAGSPG--FQGLPGPAGPPGEAGKPGEQGVPGDLGAPG-PSGARGERGFPG 683 Query: 397 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL--------VPGV 448 GV G PG AG G G PG G G +P A + A + G+ +PG Sbjct: 684 ER-GVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ-GMPGERGAAGLPGP 741 Query: 449 GVAPGVGVAPGVGVAPGV----GLAPGVGVAPGVGVAPG----VGVAPGIGPGGVAAAAK 500 G G +PG GL +G PG APG G + GP G A Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGPIG-PPGPAGAPGDKGESGPSGPAGPTGARGAPG 800 Query: 501 SAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA 559 + A GA G PG G G AG PG AG PG GA Sbjct: 801 DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGA-P 859 Query: 560 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL- 618 AK A+ A PG G GA G VG PG AGP A G G AG Sbjct: 860 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 619 GGLG-------VGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 664 G +G G G PG G G P P A + GV PG FPG Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Score = 169 bits (427), Expect = 1e-41 Identities = 224/649 (34%), Positives = 254/649 (39%), Gaps = 64/649 (9%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAG-----AGLGAGLGAFPAVTF 77 P P G PG G+PG P GP G P P P GL G G + ++ Sbjct: 122 PRGPAGPPGR--DGIPGQPGLP--GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISV 177 Query: 78 PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVG 135 PG + P G A G G PG G ++G + P+ PG K G G Sbjct: 178 PGPMGPSGPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG 236 Query: 136 LPGVYPGGVLP----GAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 190 PG PG P GAR PG LPG+ G G+ GA GP G +P Sbjct: 237 KPG-RPGERGPPGPQGARGLPGTAGLPGMKGHRGFS----GLDGAKGDAGPAGPKG--EP 289 Query: 191 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGTGVGPQAAAA 247 G P AP G GLP G+ P GP G GA G AG P T GP Sbjct: 290 GSP--GENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGPPGPT--GPAGPPG 344 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 AK AG G G GV G PG PG G AG PA A A Sbjct: 345 FPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG---PAGNPGADGQPGAKGAN 400 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVVPGA-GIPGA-AVPGVVSPE 361 A G + G PGF PG G G PG G PG +G P PG+ G GA PG V + Sbjct: 401 GAPG-IAGAPGF-PGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457 Query: 362 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 A + K GAR G G+P G G G G G G PG GV G G G G Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLP----GPPGERG-GPGSRGFPGADGVAGPKGPAGERG 512 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 481 PG P+ A + + GL PG G +PG G G PG Sbjct: 513 SPGPA-GPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570 Query: 482 PGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGV 539 PG G A +G G AA K + +G AG G G PG AG Sbjct: 571 PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGE 630 Query: 540 PGLGVGAGVPGFGAVPG-ALAAAKAAKYG-AAVPGVLGG---LGALGGVGIPG--GVVG- 591 G AG PGF +PG A +A K G VPG LG GA G G PG GV G Sbjct: 631 RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGP 690 Query: 592 AGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGL-GVPGVGGLGGIP 638 GPA A A G GA G G G GL G+PG G G+P Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP 739 Score = 152 bits (384), Expect = 1e-36 Identities = 221/732 (30%), Positives = 257/732 (35%), Gaps = 117/732 (15%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPG-GVPGGVFYPALGPGGKPLKPVPGGLA 61 G T A PG + + P P G G G PG P GP G+ P G Sbjct: 443 GDTGAKGEPGPV----GVQGPPGPAGEEGKRGARGEPGPTGLP--GPPGERGGPGSRGFP 496 Query: 62 GA-GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP 120 GA G+ G PG P G A G G+PG GL S G+ P Sbjct: 497 GADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-------PGEAGLPGAKGLTGSPGSPGP 549 Query: 121 QPGAGVKPGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGVPTGAGVK--PKAPG 171 G PG G PG PG PGAR FPG G P AG + P PG Sbjct: 550 DGKTG-PPGPAGQDGRPGP-PGP--PGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPG 605 Query: 172 VGGAFAGIPGVGPFGGPQPGVPLGY-----PIKAPK---LPGGYGLPYTTGK-----LPY 218 G G G P P P G P +P LPG G P GK +P Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665 Query: 219 GYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 271 G G +GA G+ G+P GV GP+ A A AK AGA G G G Sbjct: 666 DLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG 725 Query: 272 VPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 326 + G+PG +PG G G P A + K G + P GP PG G Sbjct: 726 LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPIGPPGPAGAPGDKGE 783 Query: 327 PGA----------GVPG----VGVPG-AGIPVVPGA-------GIPG-------AAVPGV 357 G G PG G PG AG PGA G PG A PG Sbjct: 784 SGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGP 843 Query: 358 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 417 P GA+ G G P GA GFPG G G PG +G G G P Sbjct: 844 AGPAGPPGPIGNVGAPGAKGARGSAGPP----GATGFPG-AAGRVGPPGPSGNAGPPGPP 898 Query: 418 GVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 477 G G G G P + A + + G PG G +PG A G APG G Sbjct: 899 GPAGKEG-GKGPRGETGPAGRPGEVG-PPGPPGPAGEKGSPG---ADGPAGAPGTPGPQG 953 Query: 478 VGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 536 + GV PG G G + + + A+ G P +G PGL Sbjct: 954 IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP-----MGPPGL--- 1005 Query: 537 AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAA 596 AG PG G PG PG + AK G G GA G G PG V AG + Sbjct: 1006 AGPPGESGREGAPGAEGSPGR-DGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG 1064 Query: 597 AAAAAKAAAKAAQFGLVGAAGLGGL-----------GVGGLGVPGVGGLGGI--PPAAAA 643 A A G VGA G G G G+ G G G+ PP Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124 Query: 644 KAAKYGVAARPG 655 + G + G Sbjct: 1125 SPGEQGPSGASG 1136 Score = 150 bits (378), Expect = 5e-36 Identities = 214/682 (31%), Positives = 243/682 (35%), Gaps = 107/682 (15%) Query: 25 RPG--GVPGA-----IPGGV-PGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFP--- 73 RPG G+PGA PG P G P GP G+ +P P G GA AG+ FP Sbjct: 528 RPGEAGLPGAKGLTGSPGSPGPDGKTGPP-GPAGQDGRPGPPGPPGARGQAGVMGFPGPK 586 Query: 74 -AVTFPGAL----VPGGVADAAAAYKAAKAGA----------------GLGGVPGVGGLG 112 A PG VPG A K +AGA G G PG GL Sbjct: 587 GAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLP 646 Query: 113 VSAGAVVPQPGAGVKPGK--VPG-VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK- 168 AG PG KPG+ VPG +G PG P G FPG + G P AG + Sbjct: 647 GPAGP----PGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGVQGPPGPAGPRGAN 700 Query: 169 -APGVGGAF--AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 225 APG GA AG PG P PG+ P G GLP G GP G Sbjct: 701 GAPGNDGAKGDAGAPGA-PGSQGAPGLQ-----GMPGERGAAGLPGPKGDRGDA-GPKGA 753 Query: 226 AGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG 284 G+ GK G TG +GP A A +G AG G G G PG PG G Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP-PGPAG 812 Query: 285 IAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPG 333 AG G P A A G P GP G VG PGA G PG Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872 Query: 334 V-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPG-VGVGGIPTYG- 388 G PGA V P A PG P + G RPG VG G P Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932 Query: 389 ----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAK 438 GA G PG G+ G GV G+PG G G G+PG P Q + A Sbjct: 933 EKGSPGADGPAGAPGTPG-PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS 991 Query: 439 AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV----GVAPGIGPGG 494 + PG PG+ PG G APG +PG +PG G GP G Sbjct: 992 GERGP--PGPMGPPGLAGPPGESGREG---APGAEGSPGRDGSPGAKGDRGETGPAGPPG 1046 Query: 495 VAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAV 554 A + V + G P VG VGA P Sbjct: 1047 APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP---------------VGARGPAGPQG 1091 Query: 555 PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVG 614 P + + G G G G G PG GP+ A+ A G G Sbjct: 1092 PRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151 Query: 615 AAGLGGLGVGGLGVPGVGGLGG 636 GL GL G +G PG G G Sbjct: 1152 KDGLNGL-PGPIGPPGPRGRTG 1172 Score = 144 bits (362), Expect = 3e-34 Identities = 198/620 (31%), Positives = 216/620 (34%), Gaps = 91/620 (14%) Query: 23 PSRPGGVPGAI-PGGVPG--GVFYPALGPGGKPLKP----VPGGLAGAGLGAGLG--AFP 73 P+ P G G P G PG G+ PA GP G+ KP VPG L G G FP Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPA-GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP 682 Query: 74 AVTF----PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 129 PG P G A+ A AK AG G PG S GA PG PG Sbjct: 683 GERGVQGPPGPAGPRG-ANGAPGNDGAKGDAGAPGAPG------SQGA----PGLQGMPG 731 Query: 130 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQ 189 + GLPG P G A P GA P GV G I GP G P Sbjct: 732 ERGAAGLPG--PKGDRGDAG----------PKGADGSPGKDGVRGLTGPIGPPGPAGAPG 779 Query: 190 ------PGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGV-- 240 P P G P A PG G P G P G+ GP G G G G P G Sbjct: 780 DKGESGPSGPAG-PTGARGAPGDRGEPGPPG--PAGFAGPPGADGQPGAKGEPGDAGAKG 836 Query: 241 --GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA-AAAA 297 GP A A GA G G AG PG G PG G G P+ A Sbjct: 837 DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG-FPGAAGRVGPPGPSGNAGPP 895 Query: 298 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGV 357 A K G GP PG VG PG P AG PGA P A PG Sbjct: 896 GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP------AGEKGSPGADGP-AGAPGT 948 Query: 358 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPG 412 P+ A G R G G+P G G PG G G PG G PG Sbjct: 949 PGPQGIAGQRGVVGLPGQRGERGFPGLP----GPSGEPGKQGPSGASGERGPPGPMGPPG 1004 Query: 413 VGGVPGVG---GVPGVGISPEAQAAAAAKAAKYGLVP-GVGVAPGVGVAPG-VGVAPGVG 467 + G PG G PG SP + AK + P G APG APG VG A G Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG 1064 Query: 468 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA--QLRAAAGLGA-----G 520 G A G VG GP G + + R +GL G Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124 Query: 521 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 580 PG G G G PG G G +PG + PG G G Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGP----------PGPRGRTGDA 1174 Query: 581 GGVGIPGGVVGAGPAAAAAA 600 G VG PG GP +A Sbjct: 1175 GPVGPPGPPGPPGPPGPPSA 1194 Score = 139 bits (349), Expect = 1e-32 Identities = 183/561 (32%), Positives = 200/561 (35%), Gaps = 53/561 (9%) Query: 101 GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP 160 G G PG GLG G PQ G G+ +PG P G PG PG P Sbjct: 145 GPPGPPGPPGLG---GNFAPQLSYGYDEKSTGGISVPG--PMGPSGPRGLPGPPGAPG-P 198 Query: 161 TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY 220 G P PG GA + GP G P G K P PG G P Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK-PGRPGERGPP---------- 247 Query: 221 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 280 GP G G G AG P G + + AK AG AG G G G PG + Sbjct: 248 GPQGARGLPGTAGLP-----GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQM- 301 Query: 281 GIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA 339 G G+ G G P A A A GAA P GP G G PGA VG G Sbjct: 302 GPRGLPGERGRPGAPGPAGARGNDGATGAAG---PPGPTGPAGPPGFPGA----VGAKGE 354 Query: 340 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPG 396 P P V G P A AA A GA +PG G G P GA GFPG Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI-AGAPGFPG 413 Query: 397 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL--VPGVGVAPGV 454 G G G G PG G G G PG + A + G+ PG G Sbjct: 414 -ARGPSGPQGPGGPPGPKGNSGEPGAPG----SKGDTGAKGEPGPVGVQGPPGPAGEEGK 468 Query: 455 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRA 513 A G G+ PG PG PG GVA GP G A S K Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA---GPKGPAGERGSPGPAGPKGSPGE 525 Query: 514 AAGLG-AGIP---GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 569 A G AG+P GL G PG G PG G PG PGA A + Sbjct: 526 AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF-PG 584 Query: 570 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 629 G G G G G+PG GPA A A G G G G G G Sbjct: 585 PKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG-PAGSPGFQ 643 Query: 630 GVGGLGGIPPAAAAKAAKYGV 650 G+ G G PP A K + GV Sbjct: 644 GLPGPAG-PPGEAGKPGEQGV 663 Score = 111 bits (277), Expect = 2e-24 Identities = 159/499 (31%), Positives = 178/499 (35%), Gaps = 111/499 (22%) Query: 221 GPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKF----------GAGAAGV 263 GP G AG G+ G P G+ GP A + G G Sbjct: 121 GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP 180 Query: 264 LPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYG--------AAAGLVP 314 + G G+PG PGA PG G G G P A+ G AG P Sbjct: 181 MGPSGPRGLPGPPGA-PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG-KP 238 Query: 315 GGPG-FGP----GVVGVPG-AGVPGV-------GVPGA----------GIPVVPGA-GIP 350 G PG GP G G+PG AG+PG+ G+ GA G P PG G P Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298 Query: 351 G----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPG 406 G +PG A A GA G G PT G GFPG VG G G Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG-PTGPAGPPGFPG-AVGAKGEAG 356 Query: 407 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 466 G G G GV G PG P A AA A PG PG A G APG+ Sbjct: 357 PQGPRGSEGPQGVRGEPG----PPGPAGAAGPAGN----PGADGQPG---AKGANGAPGI 405 Query: 467 GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 APG A G G G PG G G A S AK G PG Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK-----------GEPG-- 452 Query: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG---- 581 VGV G AG G G PG +PG PG GG G+ G Sbjct: 453 -PVGVQGPPGPAGEEGKRGARGEPGPTGLPGP-------------PGERGGPGSRGFPGA 498 Query: 582 -GVGIPGGVVG----AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 636 GV P G G GPA + A + + GL GA GL G G PG G G Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL----TGSPGSPGPDGKTG 554 Query: 637 IPPAAAAKAAKYGVAARPG 655 PP A + + G PG Sbjct: 555 -PPGPAGQDGRPGPPGPPG 572 Score = 102 bits (253), Expect = 2e-21 Identities = 148/442 (33%), Positives = 162/442 (36%), Gaps = 55/442 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYP-----ALGPGGKPLKPVPGGLAG--------------A 63 P P G PG P G P A G G+P P P G AG Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830 Query: 64 GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ-P 122 GA A P A PG + + A AK G G PG G +AG V P P Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAP--GAKGARGSAGPPGATGFPGAAGRVGPPGP 888 Query: 123 GAGVKPGKVPGVGLP--GVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIP 180 P PG G P G A PG PG P AG K +PG G AG P Sbjct: 889 SGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG-SPGADGP-AGAP 946 Query: 181 GV-GPFG-GPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGY----GPGGVAGAA 229 G GP G Q GV +G P + P LPG G P G P G GP G G Sbjct: 947 GTPGPQGIAGQRGV-VGLPGQRGERGFPGLPGPSGEPGKQG--PSGASGERGPPGPMGPP 1003 Query: 230 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA--IPGIGGIAG 287 G AG P +G + A A GA G G AG PG PGA PG G AG Sbjct: 1004 GLAGPPGESG--REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAG 1061 Query: 288 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPGAGIPVV 344 G A A GA P GP G G G G+ G G G P Sbjct: 1062 KSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPG 1121 Query: 345 PGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGI 404 P G PG P S A + +A GA G+ G+P G G PG G G Sbjct: 1122 P-PGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLP----GPIGPPG-PRGRTGD 1173 Query: 405 PGVAGVPGVGGVPGVGGVPGVG 426 G G PG G PG G P G Sbjct: 1174 AGPVGPPGPPGPPGPPGPPSAG 1195 Score = 80.9 bits (198), Expect = 4e-15 Identities = 118/371 (31%), Positives = 135/371 (36%), Gaps = 49/371 (13%) Query: 23 PSRPGGVPGAI-----PG--------GVPGGVFYPAL-------GPGGKPLKPVPGGLAG 62 P+ P G PG I PG G PG +P GP G P P G AG Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902 Query: 63 AGLGAG-LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAGAVV 119 G G G PG + P G A A AG G PG G+ G VV Sbjct: 903 KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG-VV 961 Query: 120 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARF-----PGVGVLPGV--PTGAGVKPKAPGV 172 PG + G PG+ P PG P PG PG+ P G + APG Sbjct: 962 GLPGQRGERG-FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020 Query: 173 GGAFA--GIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 229 G+ G PG G G P P G P AP PG G +G G G AG A Sbjct: 1021 EGSPGRDGSPGAKGDRGETGPAGPPGAP-GAPGAPGPVGPAGKSGDR----GETGPAGPA 1075 Query: 230 GKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV 288 G G G GPQ + + G G G G PG PG+ PG G +G Sbjct: 1076 GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS-PGEQGPSGA 1134 Query: 289 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVV 344 PA +A A GL GP PG G G P VG PG G P Sbjct: 1135 SGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPGPRGRTGDAGP-VGPPGPPGPPGPPGP 1191 Query: 345 PGAGIPGAAVP 355 P AG + +P Sbjct: 1192 PSAGFDFSFLP 1202 Score = 80.5 bits (197), Expect = 5e-15 Identities = 105/341 (30%), Positives = 127/341 (37%), Gaps = 30/341 (8%) Query: 345 PGAGIP-GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 403 PGA +P G P V P+ + + P G P G G PG G Sbjct: 82 PGAEVPEGECCP--VCPDGSESPTDQETTGVEGPKGDTG--PRGPRGPAGPPGRD----G 133 Query: 404 IPGVAGVPGVGGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVG 461 IPG G+PG G PG G PG+G +P+ K+ VPG G PG Sbjct: 134 IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPP 193 Query: 462 VAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQL-----RAAA 515 APG G PG A G +G GP G A K + + A Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253 Query: 516 GL--GAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGALA----AAKAAKY 566 GL AG+PG+ G GL AG G G PG PG + + + Sbjct: 254 GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313 Query: 567 GAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 625 GA P G G GA G G PG AGP A A +A G G+ G G+ G Sbjct: 314 GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR-GE 372 Query: 626 LGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 664 G PG G G P A + G PG +P FPG Sbjct: 373 PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 170 bits (430), Expect = 5e-42 Identities = 207/683 (30%), Positives = 261/683 (38%), Gaps = 103/683 (15%) Query: 26 PGGVPGAIPGG---------VPGGVFYPAL-GPGGKPLK--PVPGGLAGAGLGAGLGAFP 73 P G PG P G PGG P L GP G+P K P+PG GL G FP Sbjct: 602 PPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG-FP 660 Query: 74 AVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 129 FPG PG + G G G PG G+ G + P PG +PG Sbjct: 661 GPQGDRGFPGT--PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP-PGTPGRPG 717 Query: 130 KVPGVGLPGVY-----PGGVLPGARFPGVGVLPGVPTGAGVK-----PKAPGVGGAFA-- 177 G PGV PG LPG + G+ LPG+P G K P PG GA Sbjct: 718 FNGLPGNPGVQGQKGEPGVGLPGLK--GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPP 775 Query: 178 GIPGV----GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 229 G+ G+ GP G P PGVP P A PGG G P +G P G+ G Sbjct: 776 GLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSG-------PPGIKGEK 828 Query: 230 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGV 288 G G+P GP+ A +G G LPG GA G+PG PG+ +G + Sbjct: 829 GFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG-LPGQQGAPGIPGFPGSKGEMGVMGTP 887 Query: 289 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 348 G P + A + G GP PG+ G G VG+PG Sbjct: 888 GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG----DVGLPGK--------- 934 Query: 349 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 408 PG + + G + +G P G+ G P G G+PG Sbjct: 935 ------PGSMDKVDMGSMKGQKGDQGEKGQIG----PIGEKGSRGDP----GTPGVPGKD 980 Query: 409 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-VPGVGVAPGVGVAPGVGVAPGVG 467 G G G PG G PG+ +P A K + G+ +PG GV PG +PG+ Sbjct: 981 GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLP 1040 Query: 468 LAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIP 522 G G PG+G+ PG+ G G+A S + K + G+ G+ Sbjct: 1041 GDKGAKGEKGQAGPPGIGI-PGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLK 1099 Query: 523 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 G VG PG G+PG G+PG +PG K A +PG G G G Sbjct: 1100 GSPGSVGYPG---SPGLPGEKGDKGLPGLDGIPG-------VKGEAGLPGTPGPTGPAGQ 1149 Query: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQF-GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 641 G PG P +A + F G GA G G G +G PG+ G GIP Sbjct: 1150 KGEPGS--DGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG-SKGEVGFPGLAGSPGIP--- 1203 Query: 642 AAKAAKYGVAARPGFGLSPIFPG 664 + G PG P PG Sbjct: 1204 -GSKGEQGFMGPPGPQGQPGLPG 1225 Score = 162 bits (410), Expect = 9e-40 Identities = 226/724 (31%), Positives = 282/724 (38%), Gaps = 118/724 (16%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALG-PGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPG 79 P RPG G+PG GV G P +G PG K L +PG G +G G Sbjct: 713 PGRPGFNGLPGN--PGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHG 770 Query: 80 ALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSA--GAVVPQPGAGVKPGKVPGVG 135 A+ P G+ G GVPG+G G G P PG PG G Sbjct: 771 AIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP-PGLSGPPGIKGEKG 829 Query: 136 LPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-------VGPFGG 187 PG +PG +PG + G LPG+ TG P PG GA GIPG +G G Sbjct: 830 FPG-FPGLDMPGPKGDKGAQGLPGI-TGQSGLPGLPGQQGA-PGIPGFPGSKGEMGVMGT 886 Query: 188 P-QPGVPLGYPIKAPKLPG---GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 243 P QPG P P+ AP LPG +G P ++G G G+ G G G P G + Sbjct: 887 PGQPGSP--GPVGAPGLPGEKGDHGFPGSSGPR----GDPGLKGDKGDVGLPGKPGSMDK 940 Query: 244 AAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-------GTPAAAA 295 + G G G + G G PG PG +PG G AG G P + Sbjct: 941 VDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG-VPGKDGQAGQPGQPGPKGDPGISG 999 Query: 296 AAAAAAKAAKYGAAAGL-VPGGPGFGPGVVGVPGA-GVPGV-GVPGA----GIPVVPGAG 348 A G+ G+ +PG PG GV G+PG G PG+ G GA G PG G Sbjct: 1000 TPGAPGLPGPKGSVGGMGLPGTPG-EKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIG 1058 Query: 349 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 408 IPG + G + A + G + +G+ G+P G G PG VG G PG+ Sbjct: 1059 IPG--LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPG-SPGLKGSPG-SVGYPGSPGLP 1114 Query: 409 GVPGVGGVPGVGGVPGV----GI----SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 460 G G G+PG+ G+PGV G+ P A + G +PG G PG Sbjct: 1115 GEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG-IPGSAGEKGEPGLPGR 1173 Query: 461 GVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-------------GPGGVAAAAKSAAKVAA 507 G PG A G + G PG+ +PGI GP G S Sbjct: 1174 GF-PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATE 1232 Query: 508 KAQLRAAAGLGAGIPGLGVGVGVPGL----GVGA--------GVPGLGVGAGVPGFGAVP 555 + G+PGL +G PGL GV G PG+ G PGF +P Sbjct: 1233 GPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMP 1292 Query: 556 G-----ALAAAKAAKYGAAVPGVLG--GLGALGGV-------GIPGGVVGAGPAAAAAAA 601 G + +K VPG G GL L G+ G+PG GP Sbjct: 1293 GIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPY 1352 Query: 602 KAAAKAAQFGLVGAAGLGGL-GVGGL----GVPGVGGLGGIPPAAAAKAAKYGVAARPGF 656 + GL G G GL G+ GL G GV GL GIP G PGF Sbjct: 1353 DII--KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIP----------GPPGIPGF 1400 Query: 657 GLSP 660 +P Sbjct: 1401 DGAP 1404 Score = 141 bits (355), Expect = 2e-33 Identities = 212/697 (30%), Positives = 260/697 (37%), Gaps = 181/697 (25%) Query: 26 PGGVPGAIPGGVPGGVFYPALGPGGKPLKPV---PGGLAGAGLGAGLGAFPAVTFPGALV 82 P G+PG++ G PG P +GP G P P GL+G G FP FPG + Sbjct: 786 PPGLPGSV--GSPG---VPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG--FPGLDM 838 Query: 83 PGGVADAAAAYKAAKAGA-------GLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKVPG 133 PG D A G G G PG+ G S G V+ PG PG V Sbjct: 839 PGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA 898 Query: 134 VGLPGVYPGGVLPGARFP----------GVGVLPGVP----------------------- 160 GLPG PG+ P G LPG P Sbjct: 899 PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ 958 Query: 161 ------TGAGVKPKAPGVGG--AFAGIPGV-GPFGGP----QPGVPLGYPIKAPK-LPGG 206 G+ P PGV G AG PG GP G P PG P G P PK GG Sbjct: 959 IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP-GLP--GPKGSVGG 1015 Query: 207 YGLPYTTGKL-------PYGY----GPGGVAGAAGKAGYPTGTGV-------GPQAAAAA 248 GLP T G+ P G G G G G+AG P G G+ G Q A Sbjct: 1016 MGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG-PPGIGIPGLRGEKGDQGIAGF 1074 Query: 249 AAKAAAKFGAGAAGV--LPG----------VGGAGVPGVPG-----AIPGIGGIAGV--- 288 K G+ G+ +PG VG G PG+PG +PG+ GI GV Sbjct: 1075 PGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGE 1134 Query: 289 -GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG-------------V 334 G P A + + G+ +PG G G G+PG G PG V Sbjct: 1135 AGLPGTPGPTGPAGQKGEPGSDG--IPGSAG-EKGEPGLPGRGFPGFPGAKGDKGSKGEV 1191 Query: 335 GVPG-AGIPVVPGA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 385 G PG AG P +PG+ G PG PG+ A K + G + G+ G+P Sbjct: 1192 GFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR-GPQGQPGLPGLP 1250 Query: 386 TYGVGAGGFPGF-GV----------GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAA 434 +G G PG GV G G+PG G PG G+PG+GG PG+ Sbjct: 1251 G-PMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGI--------- 1300 Query: 435 AAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPG 493 +K + P PGV PG G+ G+ G PG PG GP Sbjct: 1301 ---TGSKGDMGP-----PGV---PGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPP 1349 Query: 494 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 553 G K + GL G+PG GV GL G+PG G+PGF Sbjct: 1350 GPYDIIKGEPGLPGPEGPPGLKGL-QGLPGPKGQQGVTGL---VGIPG---PPGIPGFDG 1402 Query: 554 VPGALAAAKAAKYGAAVP-GVLGGLGALGGVGIPGGV 589 PG + + G A P G G G G G+PG + Sbjct: 1403 APG-----QKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1434 Score = 132 bits (332), Expect = 1e-30 Identities = 209/702 (29%), Positives = 257/702 (36%), Gaps = 103/702 (14%) Query: 22 HPSRPG--GVPGAI----PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 +P PG G+PG P G+PG G G+ P GL G G P + Sbjct: 101 YPGNPGLPGIPGQDGPPGPPGIPG-----CNGTKGERGPLGPPGLPGFAGNPGPPGLPGM 155 Query: 76 TF-PGAL---VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPG 129 PG + VPG + + G G+PG+ G G P PG PG Sbjct: 156 KGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215 Query: 130 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP-------GVGG--AFAGIP 180 + +GL P G GV PGVP A V+ K G G F G+P Sbjct: 216 EKGQMGLSFQGPKG---DKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMP 272 Query: 181 GVGPFGGPQPGVPLGYPIK--------APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKA 232 GVG G P P G P K +P PG G P G+ GP G G AG Sbjct: 273 GVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR----QGPQGEKGEAGPP 328 Query: 233 GYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 291 G P G GP + + G G G G PG+PG PG G+ G Sbjct: 329 GPPGIVIGTGP------LGEKGERGYPGTPGPRGEPGPKGFPGLPGQ-PGPPGLPVPGQA 381 Query: 292 AAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV---------GVPG- 338 A + G +PG G PG G PG G PG G PG Sbjct: 382 GAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGD 441 Query: 339 AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPG-------VGVGGIPTYGVG 390 G P +PG PG G + + Y PG +G G P G Sbjct: 442 QGPPGIPGQ--PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG-AKG 498 Query: 391 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG---VGISPEAQAAAAAKAAKYGLV-- 445 G PG GV G+PG G PG+ G PG G PG + + + G+ Sbjct: 499 DRGLPGRD-GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGR 557 Query: 446 ---PGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 501 PG PG+ PG +PG VGL G GVG G GP G Sbjct: 558 AGSPGRDGHPGL---PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYG----P 610 Query: 502 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA 561 A + K Q A G G PGL G PG V +PG G+PG PG Sbjct: 611 AGPIGDKGQ--AGFPGGPGSPGLPGPKGEPGKIV--PLPGPPGAEGLPGSPGFPGP-QGD 665 Query: 562 KAAKYGAAVPGVLGGLGALG--GVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAA 616 + PG+ G GA+G G+G PG G G G + GL G Sbjct: 666 RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNP 725 Query: 617 GL-GGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 655 G+ G G G+G+PG+ GL G+P P + GV PG Sbjct: 726 GVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPG 767 Score = 114 bits (286), Expect = 2e-25 Identities = 148/475 (31%), Positives = 183/475 (38%), Gaps = 95/475 (20%) Query: 23 PSRPG--------GVPGA--IPG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLG 70 P +PG G PGA +PG G GG+ P PG K + +PG GL G Sbjct: 986 PGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGT-PGEKGVPGIPGPQGSPGLPGDKG 1044 Query: 71 AFPA---VTFPGALVPG--------GVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 117 A PG +PG G+A + K K G+ G+PG GL S G+ Sbjct: 1045 AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104 Query: 118 VVPQPGAGVKPGK-----VPGV-GLPGVYPGGVLPGARFP-------GVGVLPGVPTGAG 164 V PG+ PG+ +PG+ G+PGV LPG P G G+P AG Sbjct: 1105 V-GYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163 Query: 165 VKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGG 224 K + G F G PG G + V P L G G+P + G+ + GP G Sbjct: 1164 EKGEPGLPGRGFPGFPGAKGDKGSKGEVGF------PGLAGSPGIPGSKGEQGF-MGPPG 1216 Query: 225 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPGVGGA----GVPGVPGA 278 G G G P GP+ + G G LPG+ G G PG PGA Sbjct: 1217 PQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGA 1276 Query: 279 IPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG 333 PG+ G G G P + G PG PGF G G+PG G+ G Sbjct: 1277 -PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-----PGVPGF-QGPKGLPGLQGIKG 1329 Query: 334 ----VGVPGA-GIPVVPGA--------GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVG 380 GVPGA G+P PG G PG +PG P G + G Sbjct: 1330 DQGDQGVPGAKGLPGPPGPPGPYDIIKGEPG--LPGPEGPPGLKGLQGLPGPKGQQGVTG 1387 Query: 381 VGGIPTYGVGAGGFPGFG-----------VGVGGIPGVAGVPGVGGVPGVGGVPG 424 + GIP G G PGF G G G G PG G+PG G PG Sbjct: 1388 LVGIP----GPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438 Score = 86.7 bits (213), Expect = 7e-17 Identities = 156/537 (29%), Positives = 181/537 (33%), Gaps = 113/537 (21%) Query: 201 PKLPGGYGLPYTTGKLPYG-YGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 258 P L G G P G P G GP G G G+ G P G GP Sbjct: 54 PGLQGVIGFPGMQG--PEGPQGPPGQKGDTGEPGLPGTKGTRGPP--------------- 96 Query: 259 GAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG----VGTPAAAAAA------AAA 300 GA+G G G+PG+PG IPG G G +G P A Sbjct: 97 GASGY---PGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153 Query: 301 AKAAKYGAAAGLVPG----GPGFGPGVVGVPG-AGVPG----VGVPG-AGIPVVPG-AGI 349 G G VPG G PG+ G PG G+PG VG PG G P PG G Sbjct: 154 GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGP 213 Query: 350 PG------------------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 385 PG VPG + A K K G + G G+P Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEK-GQKGEPGFQGMP 272 Query: 386 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GI----SPEAQAAAAAKAA 440 GVG G PG G G PG G G G PG G PG G+ P+ + A Sbjct: 273 --GVGEKGEPG-KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPG 329 Query: 441 KYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAK 500 G+V G G G G PG PG PG+ PG PG+ G A A Sbjct: 330 PPGIVIGTGPLGEKG-ERGYPGTPGPRGEPGPKGFPGLPGQPG---PPGLPVPGQAGAPG 385 Query: 501 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF-GAVPGALA 559 + K G P G +PG G+PG G PG G G + Sbjct: 386 FPGERGEKGD--------RGFP----GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVE 433 Query: 560 AAKAAKYGAAVPGVLGGLGALGGVGIPG---------GVVG-AGPAAAAAAAKAAAKAAQ 609 PG+ G G +G +G G + G GP Q Sbjct: 434 CQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQ 493 Query: 610 FGLVGAAGLGGL-GVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G G GL G GV G+ G G GL G P A Y G P FPG Sbjct: 494 PGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPG 550 Score = 82.8 bits (203), Expect = 1e-15 Identities = 112/372 (30%), Positives = 140/372 (37%), Gaps = 62/372 (16%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--------GVPG--AIPG-----GVPGGVFYPALG 47 G+ PG+ S+ +P PG G+PG IPG G+PG G Sbjct: 1088 GIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTP--GPTG 1145 Query: 48 PGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG 107 P G+ +P G+ G+ G P FPG PG D + K GL G PG Sbjct: 1146 PAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG--FPGAKGDKGS--KGEVGFPGLAGSPG 1201 Query: 108 VGGLGVSAGAVVP-----QPGAGVKPGKVP----GVGLPGVYPGGVLPGARFPGVGVLPG 158 + G G + P QPG PG G P PG LPG PG PG Sbjct: 1202 IPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG--LPG--LPGPMGPPG 1257 Query: 159 VPTGAGVK--------PKAPGVGG-----AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPG 205 +P GVK P APGV G F G+PG+G G P P G Sbjct: 1258 LPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQG 1317 Query: 206 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL 264 GLP G G+ G G G P G+ GP + G Sbjct: 1318 PKGLP----------GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367 Query: 265 PGVGGA-GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPG 322 PG+ G G+PG G G+ G+ G+ G P A + + G A P G PG Sbjct: 1368 PGLKGLQGLPGPKGQ-QGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPG 1426 Query: 323 VVGVPGA-GVPG 333 G+PG+ G PG Sbjct: 1427 PDGLPGSMGPPG 1438 Score = 71.2 bits (173), Expect = 3e-12 Identities = 112/386 (29%), Positives = 137/386 (35%), Gaps = 99/386 (25%) Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP----GVVGVPGA-GVPGVGVPGAGIPVVP 345 PAA ++AA G AG G G GV G G G+PG+ Sbjct: 13 PAALLLHEEHSRAAAKGGCAG-----SGCGKCDCHGVKGQKGERGLPGL----------- 56 Query: 346 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAGGFPGFGVGV 401 G+ G PG+ PE + G PG+ G G P GA G+PG Sbjct: 57 -QGVIG--FPGMQGPEGPQGPPGQKGDTG-EPGLPGTKGTRGPP----GASGYPGN---- 104 Query: 402 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVG 461 PG+ G+PG G PG G+PG K + L P PG+ PG Sbjct: 105 ---PGLPGIPGQDGPPGPPGIPGCN---------GTKGERGPLGP-----PGL---PGFA 144 Query: 462 VAPGVGLAPGVGVAPG--VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 519 PG PG+ PG +G PG+ L+ G Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGM-------------------------LLKGERGF-P 178 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 GIPG G+PGL G PG G PG PG + + G + G G G Sbjct: 179 GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG-----EKGQMGLSFQGPKGDKGD 233 Query: 580 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIP 638 G G PG G A A K + G G G G+ GVG G PG G G P Sbjct: 234 QGVSGPPG---VPGQAQVQEKGDFATKGEK-GQKGEPGFQGMPGVGEKGEPGKPGPRGKP 289 Query: 639 PAAAAKAAKYGVAARPGFGLSPIFPG 664 K G PGF P +PG Sbjct: 290 ----GKDGDKGEKGSPGFPGEPGYPG 311 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 169 bits (429), Expect = 6e-42 Identities = 218/686 (31%), Positives = 250/686 (36%), Gaps = 94/686 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGG 85 P G PG P G PG +P PG + PG AG G PGA+ P G Sbjct: 175 PAGPPG--PPGPPGTSGHPG-SPGSPGYQGPPGEPGQAGPSGPPGP------PGAIGPSG 225 Query: 86 VA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKVPGVGLPGVYP 141 A D + GL G PG+ G G + G + G+ G PG+ Sbjct: 226 PAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG 285 Query: 142 GGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 LPG PG G P G +P PG GA G G P P P Sbjct: 286 ENGLPGENGAPGPMGPRGAPGERG-RPGLPGAAGARGNDGARGSDGQPGPPGP------- 337 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 259 PG G P + G G G AG+ G G P G GPQ A A G Sbjct: 338 ---PGTAGFPGSPG----AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING 390 Query: 260 AAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF 319 + G +G AG+PG PG + G G A A + K GA P G Sbjct: 391 SPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450 Query: 320 GPGVVGVPGA----------GVPGV-GVPGA----GIPVVPGA----GIPGAAVP----G 356 G+ GVPGA G PG G+PGA G P G GIPG P G Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPG--FGVGVGGIPGVAGVPG 412 P AA + + G G G+ G+P G G+ G PG G G PG G G Sbjct: 511 APGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG 570 Query: 413 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGVAPGVGVAPGV---- 466 G PGV G PG P+ A K + G PG PG G PG Sbjct: 571 PRGQPGVMGFPG----PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626 Query: 467 ----GLAP----GVGVAPGVGVAPGVGVAPG-IGPGGVAAA--AKSAAKVAAKAQLRAAA 515 P G+ PG G PG PG GP G A A A A R Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPP 686 Query: 516 GLGAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 572 GL AG PGL G G PG G AG PG AG PG +PG + G PG Sbjct: 687 GL-AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG-------ERGGLGSPG 738 Query: 573 VLGGLGALGGV---GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 629 G G GG G+PG GP A + G GA GL G+ G G P Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI-AGPRGSP 797 Query: 630 GVGGLGGIPPAAAAKAAKYGVAARPG 655 G G G PP A G PG Sbjct: 798 GERGETG-PPGPAGFPGAPGQNGEPG 822 Score = 165 bits (418), Expect = 1e-40 Identities = 218/680 (32%), Positives = 246/680 (36%), Gaps = 82/680 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 PS P G PGAI P G G G+P +P GL G G P FPG Sbjct: 211 PSGPPGPPGAIGPSGPAG----KDGESGRPGRPGERGLPGPPGIKGPAGIPG--FPGMKG 264 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPG 142 G D K GL G G+ G + G + P+ GA PG+ GLPG Sbjct: 265 HRGF-DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPR-GA---PGERGRPGLPGAAGA 319 Query: 143 GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP----QPGVPLGY-- 196 GAR P P G P +PG G G G P +PG P G+ Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG-PQGHAG 378 Query: 197 PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKF 256 P PG G P G++ GP G+ GA G G GP A A + Sbjct: 379 AQGPPGPPGINGSPGGKGEM----GPAGIPGAPGLMG-----ARGPPGPAGANGAPGLRG 429 Query: 257 GAGAAGV-----LPGV----GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 GAG G PG G AG+PGVPGA G G P A AA + G Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER---G 486 Query: 308 AAAGLVPGGPGFGPGVVGVPG-AGVPG-------VGVPGA-GIPVVPG-AGIPGA----- 352 A P GP PG G G G PG G PG G+P PG G+PG+ Sbjct: 487 APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546 Query: 353 --AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVA 408 PG + + G R GV G P GA G G G GG PG Sbjct: 547 SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG-PGPQ 605 Query: 409 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL--VPGVGVAPGVGVAPGV------ 460 G PG G G G PG P GL +PG G PG PG Sbjct: 606 GPPGKNGETGPQGPPG-PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664 Query: 461 GVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA- 519 APG G APG PG+ APG+ G + A AAG Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724 Query: 520 -GIPGLGVGVGVPGLGVGAGVPGLGVGA-GVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 577 G+PG G+G PG G PG G GA GVPG G PG G Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPG-GPGADGVPGKDGPRGPTGP-------IGPPGPAGQP 776 Query: 578 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLG 635 G G G PG AGP + G GA G G G G G PG G G Sbjct: 777 GDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEG 836 Query: 636 GIPPAAAAKAAKYGVAARPG 655 G PP A G A PG Sbjct: 837 G-PPGVAGPPGGSGPAGPPG 855 Score = 159 bits (401), Expect = 1e-38 Identities = 210/653 (32%), Positives = 242/653 (37%), Gaps = 83/653 (12%) Query: 23 PSRPGGVPGAI--PG-----GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P+ PGG G PG G+PG P G GKP +P P G AGA Sbjct: 622 PTGPGGDKGDTGPPGPQGLQGLPGTGGPP--GENGKPGEPGPKGDAGA------------ 667 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPG 133 PGA PGG DA A + GL G PG+ G AG P+ G G PG Sbjct: 668 --PGA--PGGKGDAGAP--GERGPPGLAGAPGLRG---GAGPPGPEGGKGAAGPPGPPGA 718 Query: 134 VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVP 193 G PG+ +PG R G+G PG P G +P PG G GP G P P Sbjct: 719 AGTPGLQG---MPGER-GGLGS-PG-PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772 Query: 194 LGYPIKAPKLPGGY-GLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 251 G P K GG GLP G P G G G G G AG+P G + Sbjct: 773 AGQP--GDKGEGGAPGLPGIAG--PRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 252 AAAKFGAGAA-GVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA 310 A + G G GV GG+G G PG G G P AA A G+ Sbjct: 829 APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG 888 Query: 311 GLVPGGPGFGPGVVGVPG-AGVPGV-GVPGAGIPVVPGAGIPGA-AVPGVVSPEAAAKAA 367 P GP PG G PG AG G G PG P AG PG PG P A Sbjct: 889 NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPK-GDAGQPGEKGSPGAQGPPGAPGPL 947 Query: 368 AKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 427 A GAR G G+P G G PG G+ G +G PG G+ G G PG Sbjct: 948 GIAGITGARGLAGPPGMP----GPRGSPG----PQGVKGESGKPGANGLSGERGPPG--- 996 Query: 428 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA 487 P+ A A + PG PG PG +PG G +PG APG Sbjct: 997 -PQGLPGLAGTAGE----PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP 1051 Query: 488 PG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA 546 PG +GP G + + + A A AG G PG G G G G+ Sbjct: 1052 PGPVGPAG-KSGDRGESGPAGPAGAPGPAG-SRGAPGPQGPRGDKGETGERGAAGIKGHR 1109 Query: 547 GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAK 606 G PG PG+ PG G GA+G G G GP+ + Sbjct: 1110 GFPGNPGAPGS-------------PGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGH 1156 Query: 607 AAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFG 657 G G G G G G PG G G P A G AA G G Sbjct: 1157 PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIG 1209 Score = 126 bits (317), Expect = 6e-29 Identities = 171/533 (32%), Positives = 199/533 (37%), Gaps = 91/533 (17%) Query: 160 PTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 218 P G P PG+ G G PG+ G G P P G P P Y Y + + Sbjct: 104 PQGPKGDPGPPGIPGR-NGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162 Query: 219 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 278 G GG+AG G AG P GP G +G G G G PG Sbjct: 163 GVAVGGLAGYPGPAGPP-----GPPGP------------PGTSGHPGSPGSPGYQGPPGE 205 Query: 279 IPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPG-AGVPGV 334 PG G +G G P A + A K + G PG PG PG G+ G AG+PG Sbjct: 206 -PGQAGPSGPPGPPGAIGPSGPAGKDGESGR-----PGRPGERGLPGPPGIKGPAGIPGF 259 Query: 335 -GVPG-------------AGIPVVPGA-GIPGA-AVPGVVSPEAA---------AKAAAK 369 G+ G G P + G G+PG PG + P A AA Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319 Query: 370 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 429 GAR G G P G GFPG G G G AG PG G PG G PG P Sbjct: 320 RGNDGARGSDGQPG-PPGPPGTAGFPG-SPGAKGEVGPAGSPGSNGAPGQRGEPG----P 373 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + A A PG+ +PG G PG APG+ A G G APG Sbjct: 374 QGHAGAQGPPGP----PGINGSPGGKGEMGPAGIPG---APGLMGARGPPGPAGANGAPG 426 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 549 + GG K+ AK + R G AGIP GVPG G G G P Sbjct: 427 L-RGGAGEPGKNGAK--GEPGPRGERG-EAGIP------GVPG---AKGEDGKDGSPGEP 473 Query: 550 GFGAVPGALAAAKAAKY-GAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 607 G +PGA A + G A P G+ G G G G PG AGP AA Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG---PAGPRGAAGEPGRDGVP 530 Query: 608 AQFGLVGAAGLGGLGVGGLGVPGVGGLGGI-----PPAAAAKAAKYGVAARPG 655 G+ G G G G G G PG G G PP + + GV PG Sbjct: 531 GGPGMRGMPGSPG-GPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582 Score = 125 bits (314), Expect = 1e-28 Identities = 161/523 (30%), Positives = 190/523 (36%), Gaps = 98/523 (18%) Query: 188 PQPGVPLG-------YPIKAPKLP-------GGYGLPYTTGKLPYGYGPGGVAGAAGKAG 233 P P +P G P AP P G G P G +P G G+ G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPG 133 Query: 234 YPTGTGV------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 287 P G+ GPQ + K G G+ G AG PG PG PG G G Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSGHPG 192 Query: 288 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPG----AG 340 G+P +A P GP PG +G G AG G G PG G Sbjct: 193 SPGSPGYQGPPGEPGQAG---------PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243 Query: 341 IPVVPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG-----VGA 391 +P PG AGIPG PG+ + + GA G G+P +G Sbjct: 244 LPGPPGIKGPAGIPG--FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301 Query: 392 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 451 G PG G G+PG AG G G G G PG P + AK G V G + Sbjct: 302 RGAPG-ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK-GEVGPAG-S 358 Query: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVAAAAKSAAKVAA 507 PG APG PG G PG PG+ +PG +GP G+ Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPG---PPGINGSPGGKGEMGPAGI------------ 403 Query: 508 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 567 G PGL G PG G PGL GAG PG G + + Sbjct: 404 -----------PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE-PGPRGERGE 451 Query: 568 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----G 622 A +PGV G G G G P G GA AA + A G G AG G+ Sbjct: 452 AGIPGVPGAKGEDGKDGSP-GEPGANGLPGAAGERGAP-----GFRGPAGPNGIPGEKGP 505 Query: 623 VGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 665 G G PG G P AA + + GV PG P PGG Sbjct: 506 AGERGAPGPAG----PRGAAGEPGRDGVPGGPGMRGMPGSPGG 544 Score = 100 bits (248), Expect = 6e-21 Identities = 149/490 (30%), Positives = 168/490 (34%), Gaps = 94/490 (19%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGA 80 P PG GVPG P G P GP G+P GG G AG P G Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPP-GPAGQPGDKGEGGAPGLPGIAGPRGSPGER--GE 802 Query: 81 LVPGGVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV-GLP 137 P G A A G G G PG G G G P G+G P PG G+ Sbjct: 803 TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG--PAGPPGPQGVK 860 Query: 138 GVY--PGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPL 194 G PGG PGA FPG LPG P G+ P PG G+ GP G G P Sbjct: 861 GERGSPGG--PGAAGFPGARGLPG-PPGSNGNPGPPGPSGSPGKDGPPGPAGNT--GAPG 915 Query: 195 GYPIKAPK----LPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV----GPQA 244 + PK PG G P G P G G+ GA G AG P G GPQ Sbjct: 916 SPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975 Query: 245 AAAAAAKAAAKFGAGAAGV-----LPGVGGA-------------GVPGVPGAIPGIGGIA 286 + K A +G G LPG+ G G+PG G+ G G Sbjct: 976 VKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRG 1035 Query: 287 GVGTPAAAAAAA------AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVP-------- 332 G+P A A A K G P GP PG G GA P Sbjct: 1036 ENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKG 1095 Query: 333 ------GVGVPG-AGIPVVPGA-GIPGAA-------VPGVVSPEAAAKAAAKAAKYGARP 377 G+ G G P PGA G PG A PG P + K G Sbjct: 1096 ETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG 1155 Query: 378 GVGVGGIP--------TYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGV 419 G G P G+ G PG G GG+ G A + G+GG Sbjct: 1156 HPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV-GAAAIAGIGGEKAG 1214 Query: 420 GGVPGVGISP 429 G P G P Sbjct: 1215 GFAPYYGDEP 1224 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 160 bits (405), Expect = 4e-39 Identities = 217/706 (30%), Positives = 262/706 (37%), Gaps = 137/706 (19%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAG-------------LGA 67 P PG G PG +P GP G P P GL G +G Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487 Query: 68 GLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 126 G+ P PG P G K K AG G G+ G+ PGA Sbjct: 488 GISGPPGQPGLPGLPGPPGSL-GFPGQKGEKGQAGATGPKGLPGI----------PGAPG 536 Query: 127 KPGKVPGVGLPG---VYPG-----GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAG 178 PG G PG +PG G L PG+ LPG P G+ P PG G G Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-PGLPGPKGEPGG 595 Query: 179 IPGVGPFGGP-QPGVPLGYPIK-APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 236 I G G P PG+P G P P P G+G P G+ G GVAG G+ G P Sbjct: 596 ITFKGERGPPGNPGLP-GLPGNIGPMGPPGFGPPGPVGEK----GIQGVAGNPGQPGIPG 650 Query: 237 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG------IAGVGT 290 G P K G G + G G+PG PG +PGI G I G+G Sbjct: 651 PKG-DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG-LPGIPGSKGEPGIPGIGL 708 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPGA-GIPVVPGA 347 P PG GF PG+ G PGA G PG +G+ G G P PG Sbjct: 709 PGP--------------------PGPKGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747 Query: 348 -GIPGAAVPGVVSPEAAAKAAAKAAKYGAR--------PG-VGVGGIP--TYGVGAGGFP 395 G PG A+PG P G R PG G+ G+P VG G P Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 396 GF-------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGV 448 G G+GV G PG G+PG G PG+ G+PG P PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 449 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAK 508 APG PG +PG+ G PG G+ PG PG + +S Sbjct: 868 PGAPGPIGPPG---SPGLPGKAGASGFPGTKGEMGMMGPPG-PPGPLGIPGRS------- 916 Query: 509 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA----LAAAKAA 564 G+PGL G+ G G G G PG PG L +K Sbjct: 917 -----------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 565 KYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL 618 K +PG+ G G G G+PG G+ G K Q GL+G GL Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025 Query: 619 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G +G +G PG G+ G PP + GV +PG SP PG Sbjct: 1026 KGT-IGDMGFPGPQGVEG-PPGPS------GVPGQPG---SPGLPG 1060 Score = 155 bits (393), Expect = 9e-38 Identities = 209/673 (31%), Positives = 257/673 (38%), Gaps = 95/673 (14%) Query: 18 LSILHPSRPGGVPGAI--PG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFP 73 + + P P G+PG I PG G+PG P GP G + PG G+ G Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGSPGIPGAPGPIG 875 Query: 74 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----------QP 122 PG +PG A+ + K G+ G PG G LG+ + VP QP Sbjct: 876 PPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931 Query: 123 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIP 180 G G+ G PG+ PG PG P + G G+ P PGV G + G+P Sbjct: 932 GLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGPKGYQGLP 987 Query: 181 GVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 238 G P QPG+P G P PK G GLP G + GP G+ G G G+P Sbjct: 988 GDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGDMGFPGPQ 1038 Query: 239 GV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIPGIGGIAG 287 GV GP + + + G G PG+ G+PG+PG PG GI G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 288 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGI 341 VG P + PG PGF PG G PG +G PG G+PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 342 PVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP-----TYGVGAG 392 PV G G PG P G + A + + G +PG G G P + G G Sbjct: 1150 PV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGLSGQKGDG 1207 Query: 393 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP-EAQAAAAAKAAKYGLVPGVGVA 451 G PG G G+PG G PG G PGV G PG SP A G PG Sbjct: 1208 GLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQG-PPGRPGP 1265 Query: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAA 507 G PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1266 TGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1325 Query: 508 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 567 K G PGL G PG+ +GVPG G PG PG + Sbjct: 1326 K-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1374 Query: 568 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL 626 + G G G G G+ G GP + GL G G GG G GL Sbjct: 1375 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1434 Query: 627 -GVPGVGGLGGIP 638 G PG GL G P Sbjct: 1435 PGQPGTRGLDGPP 1447 Score = 130 bits (327), Expect = 4e-30 Identities = 205/733 (27%), Positives = 258/733 (35%), Gaps = 141/733 (19%) Query: 1 MAGLTAAAPRPGVLLLLLSIL-HPSRPGGVPGAIPG---------GVPGGVFYPAL-GPG 49 + G++ AA G+ LL LS+ P+ G PG G G +P L G Sbjct: 3 LRGVSLAA---GLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHP 59 Query: 50 GKPLKPVPGGLAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGV 108 G P P P G G G P P G P G+ G G PG+ Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP-------------GFPGTPGL 106 Query: 109 GGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK 166 G+ GA PQ PG G+ G PG +PG P PG+ + G P G+ + Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGP-PGIPGMKGEP-GSIIM 163 Query: 167 PKAPGVGG--AFAGIPGV----GPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYG 219 PG G + G PG+ GP G P P P G P + P PG GLP G + Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP--PGPPGLPGPKGNMGLN 221 Query: 220 Y-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAA-AKFGAGAAGVLPGVGGAGVPGVPG 277 + GP G G G G P GP + + +F G G+ G G PG+ G Sbjct: 222 FQGPKGEKGEQGLQGPP-----GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 278 AIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA------- 329 GG G G K + G +PG PG PG G PG Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG--IPGLPG-DPGYPGEPGRDGEKGQK 333 Query: 330 ------GVPGVGVPGAGIPVVPGA-------GIPGA----AVPGVVSPEAAAKAAAKAAK 372 G PG+ +P G + G G+PG PG+ P Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLP-------- 385 Query: 373 YGARPGVGVGGIPTYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGVGGV 422 PG V G P G GFPG G+ + G PG+ G PG G+PG G Sbjct: 386 --GPPGAAVMGPP----GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 423 PGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAP 482 G I P + G G+ GV G + G+ PG P Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG---QP 496 Query: 483 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG---------- 532 G+ PG PG + + K +A GL GIPG G PG Sbjct: 497 GLPGLPG-PPGSLGFPGQKGEK--GQAGATGPKGL-PGIPGAPGAPGFPGSKGEPGDILT 552 Query: 533 ----------LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 LG G PGL G PG +PG L K G G G G G Sbjct: 553 FPGMKGDKGELG-SPGAPGLPGLPGTPGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGL 610 Query: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 642 G+PG + GP G VG G+ G+ G G PG+ G G P Sbjct: 611 PGLPGNIGPMGPPGFGPP----------GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659 Query: 643 AKAAKYGVAARPG 655 + K G+ PG Sbjct: 660 TQPGKPGLPGNPG 672 Score = 130 bits (327), Expect = 4e-30 Identities = 185/617 (29%), Positives = 227/617 (36%), Gaps = 132/617 (21%) Query: 26 PGGVPGAIPGGVPGGVFYPAL----GPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL 81 P G PG P G+PG P L G G+P P P G G+ GL PG Sbjct: 903 PPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL--------PGP- 951 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAGAVVP----QPGAGVKPGKVPG 133 PG + K K GL G+PGV G G+ P QPG PG Sbjct: 952 -PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 134 VGLPGVYPG--------GVLPGARFPGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPG 181 GLPG PG G + FPG + G P +GV +P +PG+ G G PG Sbjct: 1011 PGLPG-QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 182 VGPFGGP-------QPGVPLGYP--------IKAPKLPGGYGLPYTTGK--------LPY 218 + G P +PG+P GYP + P LPG G P G+ P Sbjct: 1070 ISSIGLPGLPGPKGEPGLP-GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128 Query: 219 GYGPGGVAGAAGKAGYPTGTGV----------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 268 GP G++G G G P G GP + AG G PG Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQP 1187 Query: 269 GAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGV 326 G G PG PG +PG+ G G G GL +PG PG PG G Sbjct: 1188 GFGNPGPPG-LPGLSGQKGDG---------------------GLPGIPGNPGL-PGPKGE 1224 Query: 327 PGA-GVPGV----GVPGAGIPVVPGA-------GIPGAAVP----GVVSPEAAAKAAAKA 370 PG G PGV G PG+ P + G G PG P G+ PE Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNG 1284 Query: 371 AKYGARPGVGVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 428 G + G G+P G G PG G G PG+ G+ G G+PGV G PG+ Sbjct: 1285 GIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ-GNPGRPGLNGMKGDPGLPGVPGFPGMK-G 1342 Query: 429 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 488 P +A + GL+ G PG+ G + + G PG+ PG+ P Sbjct: 1343 PSGVPGSAGPEGEPGLIGPPG-PPGLPGPSGQSI-----IIKGDAGPPGIPGQPGLKGLP 1396 Query: 489 GI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 547 G GP G+ GL G G G G PGL G GL G Sbjct: 1397 GPQGPQGLPGPTGPPGDPGRN-------GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1448 Query: 548 VPGFGAVPGALAAAKAA 564 G PG + A Sbjct: 1449 PDGLQGPPGPPGTSSVA 1465 Score = 114 bits (285), Expect = 3e-25 Identities = 148/434 (34%), Positives = 170/434 (39%), Gaps = 54/434 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPG-------GLAGAGLGAGLGAFPAV 75 P G PG P GVPG P L PG K K PG GL G GL +P Sbjct: 1037 PQGVEGPPG--PSGVPGQPGSPGL-PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 76 TFPGALVPGGVADAAA----AYKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVKPG 129 PG + G V D AK GL G PG G G P PG +PG Sbjct: 1094 --PG--IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 130 KVPGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFA-GIPGV-GPFG 186 V G G PG PG PG + PG +PG P G +P PG G G+PG+ G G Sbjct: 1150 PVGGGGHPG-QPGP--PGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Query: 187 -GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAA 245 G PG+P P LPG G P G P GP G G+ G A GPQ Sbjct: 1206 DGGLPGIPGN-----PGLPGPKGEPGFHG-FPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259 Query: 246 AAAAAKAAAKFGAGAAGV--LPGVGGA----GVPGVPGAIPGIGGIAGVGTPAAAAAAAA 299 + G G LPG GG G PG PG +PG+ G+ G P Sbjct: 1260 PGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG-LPGLPGLKGDQGPPGLQGNPG 1318 Query: 300 AAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPG-VGVPGAGIPVVPGAGIPGA 352 GL PG PGF G GVPG+ G PG +G PG P +PG Sbjct: 1319 RPGLNGMKGDPGL-PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP--PGLPGPSGQSI 1375 Query: 353 AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGV 410 + G P G + G+ G P G G PGF G GG G G+ Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGL 1434 Query: 411 PGVGGVPGVGGVPG 424 PG G G+ G PG Sbjct: 1435 PGQPGTRGLDGPPG 1448 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 160 bits (405), Expect = 4e-39 Identities = 217/706 (30%), Positives = 262/706 (37%), Gaps = 137/706 (19%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAG-------------LGA 67 P PG G PG +P GP G P P GL G +G Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487 Query: 68 GLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 126 G+ P PG P G K K AG G G+ G+ PGA Sbjct: 488 GISGPPGQPGLPGLPGPPGSL-GFPGQKGEKGQAGATGPKGLPGI----------PGAPG 536 Query: 127 KPGKVPGVGLPG---VYPG-----GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAG 178 PG G PG +PG G L PG+ LPG P G+ P PG G G Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-PGLPGPKGEPGG 595 Query: 179 IPGVGPFGGP-QPGVPLGYPIK-APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 236 I G G P PG+P G P P P G+G P G+ G GVAG G+ G P Sbjct: 596 ITFKGERGPPGNPGLP-GLPGNIGPMGPPGFGPPGPVGEK----GIQGVAGNPGQPGIPG 650 Query: 237 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG------IAGVGT 290 G P K G G + G G+PG PG +PGI G I G+G Sbjct: 651 PKG-DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG-LPGIPGSKGEPGIPGIGL 708 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPGA-GIPVVPGA 347 P PG GF PG+ G PGA G PG +G+ G G P PG Sbjct: 709 PGP--------------------PGPKGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747 Query: 348 -GIPGAAVPGVVSPEAAAKAAAKAAKYGAR--------PG-VGVGGIP--TYGVGAGGFP 395 G PG A+PG P G R PG G+ G+P VG G P Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 396 GF-------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGV 448 G G+GV G PG G+PG G PG+ G+PG P PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 449 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAK 508 APG PG +PG+ G PG G+ PG PG + +S Sbjct: 868 PGAPGPIGPPG---SPGLPGKAGASGFPGTKGEMGMMGPPG-PPGPLGIPGRS------- 916 Query: 509 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA----LAAAKAA 564 G+PGL G+ G G G G PG PG L +K Sbjct: 917 -----------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 565 KYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL 618 K +PG+ G G G G+PG G+ G K Q GL+G GL Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025 Query: 619 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G +G +G PG G+ G PP + GV +PG SP PG Sbjct: 1026 KGT-IGDMGFPGPQGVEG-PPGPS------GVPGQPG---SPGLPG 1060 Score = 159 bits (403), Expect = 6e-39 Identities = 209/672 (31%), Positives = 258/672 (38%), Gaps = 99/672 (14%) Query: 18 LSILHPSRPGGVPGAI--PG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFP 73 + + P P G+PG I PG G+PG P GP G + PG G+ G Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGSPGIPGAPGPIG 875 Query: 74 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----------QP 122 PG +PG A+ + K G+ G PG G LG+ + VP QP Sbjct: 876 PPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931 Query: 123 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIP 180 G G+ G PG+ PG PG P + G G+ P PGV G + G+P Sbjct: 932 GLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGPKGYQGLP 987 Query: 181 GVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 238 G P QPG+P G P PK G GLP G + GP G+ G G G+P Sbjct: 988 GDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGDMGFPGPQ 1038 Query: 239 GV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIPGIGGIAG 287 GV GP + + + G G PG+ G+PG+PG PG GI G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 288 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGI 341 VG P + PG PGF PG G PG +G PG G+PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 342 PVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP-----TYGVGAG 392 PV G G PG P G + A + + G +PG G G P + G G Sbjct: 1150 PV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGLSGQKGDG 1207 Query: 393 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAP 452 G PG G G+PG G PG G PGV G PG P A + K PG P Sbjct: 1208 GLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGPALEGPKGN--PGPQGPP 1260 Query: 453 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAK 508 G PG PG+ G+ G PG+ PG+ GP G+ K Sbjct: 1261 GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320 Query: 509 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 568 G PGL G PG+ +GVPG G PG PG + Sbjct: 1321 -----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSI 1369 Query: 569 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL- 626 + G G G G G+ G GP + GL G G GG G GL Sbjct: 1370 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP 1429 Query: 627 GVPGVGGLGGIP 638 G PG GL G P Sbjct: 1430 GQPGTRGLDGPP 1441 Score = 133 bits (334), Expect = 6e-31 Identities = 185/611 (30%), Positives = 227/611 (37%), Gaps = 126/611 (20%) Query: 26 PGGVPGAIPGGVPGGVFYPAL----GPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL 81 P G PG P G+PG P L G G+P P P G G+ GL PG Sbjct: 903 PPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL--------PGP- 951 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAGAVVP----QPGAGVKPGKVPG 133 PG + K K GL G+PGV G G+ P QPG PG Sbjct: 952 -PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 134 VGLPGVYPG--------GVLPGARFPGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPG 181 GLPG PG G + FPG + G P +GV +P +PG+ G G PG Sbjct: 1011 PGLPG-QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 182 VGPFGGP-------QPGVPLGYP--------IKAPKLPGGYGLPYTTGK--------LPY 218 + G P +PG+P GYP + P LPG G P G+ P Sbjct: 1070 ISSIGLPGLPGPKGEPGLP-GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128 Query: 219 GYGPGGVAGAAGKAGYPTGTGV----------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 268 GP G++G G G P G GP + AG G PG Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQP 1187 Query: 269 GAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGV 326 G G PG PG +PG+ G G G GL +PG PG PG G Sbjct: 1188 GFGNPGPPG-LPGLSGQKGDG---------------------GLPGIPGNPGL-PGPKGE 1224 Query: 327 PGA-GVPGV----GVPGAGIPVVPGA-GIPGA----AVPGVVSPEAAAKAAAKAAKYGAR 376 PG G PGV G PG+ P + G G PG PG+ PE G + Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEK 1284 Query: 377 PGVGVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAA 434 G G+P G G PG G G PG+ G+ G G+PGV G PG+ P Sbjct: 1285 GNPGQPGLPGLPGLKGDQGPPGLQ-GNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSGVPG 1342 Query: 435 AAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPG 493 +A + GL+ G PG+ G + + G PG+ PG+ PG GP Sbjct: 1343 SAGPEGEPGLIGPPG-PPGLPGPSGQSI-----IIKGDAGPPGIPGQPGLKGLPGPQGPQ 1396 Query: 494 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 553 G+ GL G G G G PGL G GL G G Sbjct: 1397 GLPGPTGPPGDPGRN-------GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1448 Query: 554 VPGALAAAKAA 564 PG + A Sbjct: 1449 PPGPPGTSSVA 1459 Score = 130 bits (327), Expect = 4e-30 Identities = 205/733 (27%), Positives = 258/733 (35%), Gaps = 141/733 (19%) Query: 1 MAGLTAAAPRPGVLLLLLSIL-HPSRPGGVPGAIPG---------GVPGGVFYPAL-GPG 49 + G++ AA G+ LL LS+ P+ G PG G G +P L G Sbjct: 3 LRGVSLAA---GLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHP 59 Query: 50 GKPLKPVPGGLAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGV 108 G P P P G G G P P G P G+ G G PG+ Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP-------------GFPGTPGL 106 Query: 109 GGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK 166 G+ GA PQ PG G+ G PG +PG P PG+ + G P G+ + Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGP-PGIPGMKGEP-GSIIM 163 Query: 167 PKAPGVGG--AFAGIPGV----GPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYG 219 PG G + G PG+ GP G P P P G P + P PG GLP G + Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP--PGPPGLPGPKGNMGLN 221 Query: 220 Y-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAA-AKFGAGAAGVLPGVGGAGVPGVPG 277 + GP G G G G P GP + + +F G G+ G G PG+ G Sbjct: 222 FQGPKGEKGEQGLQGPP-----GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 278 AIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA------- 329 GG G G K + G +PG PG PG G PG Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG--IPGLPG-DPGYPGEPGRDGEKGQK 333 Query: 330 ------GVPGVGVPGAGIPVVPGA-------GIPGA----AVPGVVSPEAAAKAAAKAAK 372 G PG+ +P G + G G+PG PG+ P Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLP-------- 385 Query: 373 YGARPGVGVGGIPTYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGVGGV 422 PG V G P G GFPG G+ + G PG+ G PG G+PG G Sbjct: 386 --GPPGAAVMGPP----GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 423 PGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAP 482 G I P + G G+ GV G + G+ PG P Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG---QP 496 Query: 483 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG---------- 532 G+ PG PG + + K +A GL GIPG G PG Sbjct: 497 GLPGLPG-PPGSLGFPGQKGEK--GQAGATGPKGL-PGIPGAPGAPGFPGSKGEPGDILT 552 Query: 533 ----------LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 LG G PGL G PG +PG L K G G G G G Sbjct: 553 FPGMKGDKGELG-SPGAPGLPGLPGTPGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGL 610 Query: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 642 G+PG + GP G VG G+ G+ G G PG+ G G P Sbjct: 611 PGLPGNIGPMGPPGFGPP----------GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659 Query: 643 AKAAKYGVAARPG 655 + K G+ PG Sbjct: 660 TQPGKPGLPGNPG 672 Score = 114 bits (284), Expect = 4e-25 Identities = 144/431 (33%), Positives = 167/431 (38%), Gaps = 54/431 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPG-------GLAGAGLGAGLGAFPAV 75 P G PG P GVPG P L PG K K PG GL G GL +P Sbjct: 1037 PQGVEGPPG--PSGVPGQPGSPGL-PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 76 TFPGALVPGGVADAAA----AYKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVKPG 129 PG + G V D AK GL G PG G G P PG +PG Sbjct: 1094 --PG--IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 130 KVPGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 188 V G G PG PG PG + PG +PG P G +P PG G G PG+ G Sbjct: 1150 PVGGGGHPG-QPGP--PGEKGKPGQDGIPG-PAGQKGEPGQPGFGNP--GPPGLPGLSGQ 1203 Query: 189 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 248 + L P +PG GLP G+ P +G GV G G G P GP+ Sbjct: 1204 KGDGGL------PGIPGNPGLPGPKGE-PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP 1256 Query: 249 AAKAAAKFGAGAAGV--LPGVGGA----GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 302 G G LPG GG G PG PG +PG+ G+ G P Sbjct: 1257 QGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG-LPGLPGLKGDQGPPGLQGNPGRPG 1315 Query: 303 AAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPG-VGVPGAGIPVVPGAGIPGAAVP 355 GL PG PGF G GVPG+ G PG +G PG P +PG + Sbjct: 1316 LNGMKGDPGL-PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP--PGLPGPSGQSIIIK 1372 Query: 356 GVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGV 413 G P G + G+ G P G G PGF G GG G G+PG Sbjct: 1373 GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQ 1431 Query: 414 GGVPGVGGVPG 424 G G+ G PG Sbjct: 1432 PGTRGLDGPPG 1442 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 160 bits (405), Expect = 4e-39 Identities = 217/706 (30%), Positives = 262/706 (37%), Gaps = 137/706 (19%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAG-------------LGA 67 P PG G PG +P GP G P P GL G +G Sbjct: 428 PGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487 Query: 68 GLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 126 G+ P PG P G K K AG G G+ G+ PGA Sbjct: 488 GISGPPGQPGLPGLPGPPGSL-GFPGQKGEKGQAGATGPKGLPGI----------PGAPG 536 Query: 127 KPGKVPGVGLPG---VYPG-----GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAG 178 PG G PG +PG G L PG+ LPG P G+ P PG G G Sbjct: 537 APGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL-PGLPGPKGEPGG 595 Query: 179 IPGVGPFGGP-QPGVPLGYPIK-APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 236 I G G P PG+P G P P P G+G P G+ G GVAG G+ G P Sbjct: 596 ITFKGERGPPGNPGLP-GLPGNIGPMGPPGFGPPGPVGEK----GIQGVAGNPGQPGIPG 650 Query: 237 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG------IAGVGT 290 G P K G G + G G+PG PG +PGI G I G+G Sbjct: 651 PKG-DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPG-LPGIPGSKGEPGIPGIGL 708 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPGA-GIPVVPGA 347 P PG GF PG+ G PGA G PG +G+ G G P PG Sbjct: 709 PGP--------------------PGPKGF-PGIPGPPGAPGTPGRIGLEGPPGPPGFPGP 747 Query: 348 -GIPGAAVPGVVSPEAAAKAAAKAAKYGAR--------PG-VGVGGIP--TYGVGAGGFP 395 G PG A+PG P G R PG G+ G+P VG G P Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 396 GF-------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGV 448 G G+GV G PG G+PG G PG+ G+PG P PG+ Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 449 GVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAK 508 APG PG +PG+ G PG G+ PG PG + +S Sbjct: 868 PGAPGPIGPPG---SPGLPGKAGASGFPGTKGEMGMMGPPG-PPGPLGIPGRS------- 916 Query: 509 AQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA----LAAAKAA 564 G+PGL G+ G G G G PG PG L +K Sbjct: 917 -----------GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965 Query: 565 KYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL 618 K +PG+ G G G G+PG G+ G K Q GL+G GL Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025 Query: 619 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G +G +G PG G+ G PP + GV +PG SP PG Sbjct: 1026 KGT-IGDMGFPGPQGVEG-PPGPS------GVPGQPG---SPGLPG 1060 Score = 158 bits (400), Expect = 1e-38 Identities = 209/673 (31%), Positives = 258/673 (38%), Gaps = 98/673 (14%) Query: 18 LSILHPSRPGGVPGAI--PG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFP 73 + + P P G+PG I PG G+PG P GP G + PG G+ G Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP--GPPGLDVPGPPGERGSPGIPGAPGPIG 875 Query: 74 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----------QP 122 PG +PG A+ + K G+ G PG G LG+ + VP QP Sbjct: 876 PPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931 Query: 123 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIP 180 G G+ G PG+ PG PG P + G G+ P PGV G + G+P Sbjct: 932 GLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGPKGYQGLP 987 Query: 181 GVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 238 G P QPG+P G P PK G GLP G + GP G+ G G G+P Sbjct: 988 GDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGDMGFPGPQ 1038 Query: 239 GV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIPGIGGIAG 287 GV GP + + + G G PG+ G+PG+PG PG GI G Sbjct: 1039 GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 288 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGI 341 VG P + PG PGF PG G PG +G PG G+PG Sbjct: 1099 SVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 342 PVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP-----TYGVGAG 392 PV G G PG P G + A + + G +PG G G P + G G Sbjct: 1150 PV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGLSGQKGDG 1207 Query: 393 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP-GVGVA 451 G PG G G+PG G PG G PGV G PG P A + K P G Sbjct: 1208 GLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGPALEGPKGNPGPQGPPGR 1262 Query: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAA 507 PG PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1263 PGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322 Query: 508 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 567 K G PGL G PG+ +GVPG G PG PG + Sbjct: 1323 K-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQS 1371 Query: 568 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL 626 + G G G G G+ G GP + GL G G GG G GL Sbjct: 1372 IIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431 Query: 627 -GVPGVGGLGGIP 638 G PG GL G P Sbjct: 1432 PGQPGTRGLDGPP 1444 Score = 131 bits (330), Expect = 2e-30 Identities = 185/614 (30%), Positives = 227/614 (36%), Gaps = 129/614 (21%) Query: 26 PGGVPGAIPGGVPGGVFYPAL----GPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL 81 P G PG P G+PG P L G G+P P P G G+ GL PG Sbjct: 903 PPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL--------PGP- 951 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAGAVVP----QPGAGVKPGKVPG 133 PG + K K GL G+PGV G G+ P QPG PG Sbjct: 952 -PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGN 1010 Query: 134 VGLPGVYPG--------GVLPGARFPGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPG 181 GLPG PG G + FPG + G P +GV +P +PG+ G G PG Sbjct: 1011 PGLPG-QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 182 VGPFGGP-------QPGVPLGYP--------IKAPKLPGGYGLPYTTGK--------LPY 218 + G P +PG+P GYP + P LPG G P G+ P Sbjct: 1070 ISSIGLPGLPGPKGEPGLP-GYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128 Query: 219 GYGPGGVAGAAGKAGYPTGTGV----------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 268 GP G++G G G P G GP + AG G PG Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQP 1187 Query: 269 GAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGV 326 G G PG PG +PG+ G G G GL +PG PG PG G Sbjct: 1188 GFGNPGPPG-LPGLSGQKGDG---------------------GLPGIPGNPGL-PGPKGE 1224 Query: 327 PGA-GVPGV----GVPGAGIPVVPGA-GIPGAAVP-------GVVSPEAAAKAAAKAAKY 373 PG G PGV G PG+ P + G G PG P G+ PE Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIK 1284 Query: 374 GARPGVGVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 431 G + G G+P G G PG G G PG+ G+ G G+PGV G PG+ P Sbjct: 1285 GEKGNPGQPGLPGLPGLKGDQGPPGLQ-GNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSG 1342 Query: 432 QAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI- 490 +A + GL+ G PG+ G + + G PG+ PG+ PG Sbjct: 1343 VPGSAGPEGEPGLIGPPG-PPGLPGPSGQSI-----IIKGDAGPPGIPGQPGLKGLPGPQ 1396 Query: 491 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 550 GP G+ GL G G G G PGL G GL G G Sbjct: 1397 GPQGLPGPTGPPGDPGRN-------GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDG 1448 Query: 551 FGAVPGALAAAKAA 564 PG + A Sbjct: 1449 LQGPPGPPGTSSVA 1462 Score = 130 bits (327), Expect = 4e-30 Identities = 205/733 (27%), Positives = 258/733 (35%), Gaps = 141/733 (19%) Query: 1 MAGLTAAAPRPGVLLLLLSIL-HPSRPGGVPGAIPG---------GVPGGVFYPAL-GPG 49 + G++ AA G+ LL LS+ P+ G PG G G +P L G Sbjct: 3 LRGVSLAA---GLFLLALSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHP 59 Query: 50 GKPLKPVPGGLAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGV 108 G P P P G G G P P G P G+ G G PG+ Sbjct: 60 GLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLP-------------GFPGTPGL 106 Query: 109 GGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK 166 G+ GA PQ PG G+ G PG +PG P PG+ + G P G+ + Sbjct: 107 PGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG-FPGLQGPPGP-PGIPGMKGEP-GSIIM 163 Query: 167 PKAPGVGG--AFAGIPGV----GPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYG 219 PG G + G PG+ GP G P P P G P + P PG GLP G + Sbjct: 164 SSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGP--PGPPGLPGPKGNMGLN 221 Query: 220 Y-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAA-AKFGAGAAGVLPGVGGAGVPGVPG 277 + GP G G G G P GP + + +F G G+ G G PG+ G Sbjct: 222 FQGPKGEKGEQGLQGPP-----GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRG 276 Query: 278 AIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA------- 329 GG G G K + G +PG PG PG G PG Sbjct: 277 PPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG--IPGLPG-DPGYPGEPGRDGEKGQK 333 Query: 330 ------GVPGVGVPGAGIPVVPGA-------GIPGA----AVPGVVSPEAAAKAAAKAAK 372 G PG+ +P G + G G+PG PG+ P Sbjct: 334 GDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLP-------- 385 Query: 373 YGARPGVGVGGIPTYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGVGGV 422 PG V G P G GFPG G+ + G PG+ G PG G+PG G Sbjct: 386 --GPPGAAVMGPP----GPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 423 PGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAP 482 G I P + G G+ GV G + G+ PG P Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG---QP 496 Query: 483 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG---------- 532 G+ PG PG + + K +A GL GIPG G PG Sbjct: 497 GLPGLPG-PPGSLGFPGQKGEK--GQAGATGPKGL-PGIPGAPGAPGFPGSKGEPGDILT 552 Query: 533 ----------LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 LG G PGL G PG +PG L K G G G G G Sbjct: 553 FPGMKGDKGELG-SPGAPGLPGLPGTPGQDGLPG-LPGPKGEPGGITFKGERGPPGNPGL 610 Query: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 642 G+PG + GP G VG G+ G+ G G PG+ G G P Sbjct: 611 PGLPGNIGPMGPPGFGPP----------GPVGEKGIQGV-AGNPGQPGIPGPKGDPGQTI 659 Query: 643 AKAAKYGVAARPG 655 + K G+ PG Sbjct: 660 TQPGKPGLPGNPG 672 Score = 114 bits (286), Expect = 2e-25 Identities = 148/432 (34%), Positives = 169/432 (39%), Gaps = 53/432 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPG-------GLAGAGLGAGLGAFPAV 75 P G PG P GVPG P L PG K K PG GL G GL +P Sbjct: 1037 PQGVEGPPG--PSGVPGQPGSPGL-PGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 76 TFPGALVPGGVADAAA----AYKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVKPG 129 PG + G V D AK GL G PG G G P PG +PG Sbjct: 1094 --PG--IKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149 Query: 130 KVPGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFA-GIPGV-GPFG 186 V G G PG PG PG + PG +PG P G +P PG G G+PG+ G G Sbjct: 1150 PVGGGGHPG-QPGP--PGEKGKPGQDGIPG-PAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Query: 187 -GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAA 245 G PG+P P LPG G P G P GP G G+ G A GPQ Sbjct: 1206 DGGLPGIPGN-----PGLPGPKGEPGFHG-FPGVQGPPGPPGSPGPALEGPKGNPGPQGP 1259 Query: 246 AAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 301 G G LPG GG G PG PG +PG+ G+ G P Sbjct: 1260 PGRPGFQGLPGPEGPPG-LPGNGGIKGEKGNPGQPG-LPGLPGLKGDQGPPGLQGNPGRP 1317 Query: 302 KAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPG-VGVPGAGIPVVPGAGIPGAAV 354 GL PG PGF G GVPG+ G PG +G PG P +PG + Sbjct: 1318 GLNGMKGDPGL-PGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP--PGLPGPSGQSIII 1374 Query: 355 PGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPG 412 G P G + G+ G P G G PGF G GG G G+PG Sbjct: 1375 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPG 1433 Query: 413 VGGVPGVGGVPG 424 G G+ G PG Sbjct: 1434 QPGTRGLDGPPG 1445 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 160 bits (405), Expect = 4e-39 Identities = 221/710 (31%), Positives = 280/710 (39%), Gaps = 107/710 (15%) Query: 18 LSILHPSRPGGVPGAI-PGGVPGGVFYPAL-----GPGGKPLKPVPGGLAGA-------- 63 LSI + G+PG + P G G PAL GP GK P P GL G Sbjct: 391 LSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLF 450 Query: 64 GL--GAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP 120 GL G FP + PGA P G A + + + G+PG+ G AG + Sbjct: 451 GLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAG-ING 509 Query: 121 QPGAGVKPGKVPGVGLPGV-----YPGGV-LPGAR----------FPGVGVLPGVPTGAG 164 +PG G GLPG PG + PG + G PGVP G Sbjct: 510 EPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPG 569 Query: 165 VKPK--APGVGG--AFAGIPGV------GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTT 213 +K +PG G F G+PG GP G P PG+P P G GLP Sbjct: 570 MKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLK 629 Query: 214 GKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGA-G 271 G+ + G G+ G G G P G Q K A G + PG +GG G Sbjct: 630 GQRGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GDRQEAIQPGCIGGPKG 687 Query: 272 VPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGF-GP----GVV 324 +PG+PG PG G G+ G P A A G A PG PGF GP G V Sbjct: 688 LPGLPGP-PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAV 746 Query: 325 GVPGA-GVPG-VGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGV 381 G+PG G PG +G+PG P PG G+PG + P A G G+ Sbjct: 747 GLPGPDGSPGPIGLPGPDGP--PGERGLPGEVLGAQPGPRGDA---------GVPGQPGL 795 Query: 382 GGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 441 G+P G G PGF G G+PG+ G+ G G+PG G PG+ Sbjct: 796 KGLP----GDRGPPGFR-GSQGMPGMPGLKGQPGLPGPSGQPGL---------------- 834 Query: 442 YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAK 500 YG PG+ PG APG G+ PG PG PG APG +G G++ Sbjct: 835 YG-PPGLHGFPG---APGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRG 890 Query: 501 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 560 A + + G G+ G PGL G PG+ G+PG PG + Sbjct: 891 DAGFTGEQGHPGSP-----GFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGS 945 Query: 561 AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAG- 617 A + +PG+ G G G G G G G P + G +G G Sbjct: 946 KGEAGF-FGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGY 1004 Query: 618 LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 LG G+ G+ G+PG+ G+ G+P G PG P FPG A Sbjct: 1005 LGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVA 1054 Score = 149 bits (376), Expect = 8e-36 Identities = 217/765 (28%), Positives = 278/765 (36%), Gaps = 170/765 (22%) Query: 28 GVPGAIPGGVPGGVFYPALGPGGKPLKP----------VPGGLAGAGLGA--GLGAFPAV 75 G PG P G+P +P + P G P G+ G L G+ FP + Sbjct: 246 GQPG--PNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGL 303 Query: 76 T-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVP 132 +PG G + K ++ G G G G AG P P P Sbjct: 304 RGYPGLSGEKG----SPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAK 359 Query: 133 GV-GLPGVYPGGV-LPGAR----FPGVGVLPGVPTGAGVKPKA-PGVGG--AFAGIPGVG 183 G G PG +PG PG++ PG+ PG+ G G + + PG G F G PG+ Sbjct: 360 GARGDPG-FPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIP 418 Query: 184 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GP 242 G PG P PG GLP G + +G G G AG G P G GP Sbjct: 419 ALYGGPPG-----PDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGP 473 Query: 243 QAAAAAAAKAAAKFGAGAAGVLPGVGG----AGVPGVPG--------------AIPGIGG 284 + A + G A LPG+ G AG+ G PG PG+ G Sbjct: 474 KGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKG 533 Query: 285 IAG-VGTPAAAAAAAAAAKAAKYGAAA--------------------GL-----VPGGPG 318 + G +G P A + G GL +PG PG Sbjct: 534 VPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPG 593 Query: 319 FG-------PGVVGVPGA-------GVPGVGVPG----------AGIPVVPG-AGIPG-A 352 G PG G+PG G PG+G+PG AG+P PG G PG A Sbjct: 594 DGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPA 653 Query: 353 AVPGVVSPEAAAKAAAKAAKYGA-RPGV-----GVGGI-----PTYGVGAGGFPGFGVGV 401 PG + + K A + A +PG G+ G+ PT G G PGF G Sbjct: 654 GTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF-AGA 712 Query: 402 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVG 461 G PG G+PG G G G PG I P A G +G+ PG PG Sbjct: 713 DGGPGPRGLPGDAGREGFPGPPGF-IGPRGSKGAVGLPGPDGSPGPIGL-PGPDGPPGER 770 Query: 462 VAPG--VGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG 518 PG +G PG GV PG+ PG GP G R + G+ Sbjct: 771 GLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPG----------------FRGSQGM- 813 Query: 519 AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLG 578 G+PGL G PGL +G PGL G+ GF PG + +PG+ G G Sbjct: 814 PGMPGL---KGQPGLPGPSGQPGLYGPPGLHGFPGAPG-------QEGPLGLPGIPGREG 863 Query: 579 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL----------G 627 G G PG GP + A G G G G G+ G+ G Sbjct: 864 LPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRG 923 Query: 628 VPGVGGLGGIP--------PAAAAKAAKYGVAARPGFGLSPIFPG 664 PG+ G G+P P + +A +G+ G P F G Sbjct: 924 SPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKG 968 Score = 142 bits (359), Expect = 8e-34 Identities = 196/634 (30%), Positives = 247/634 (38%), Gaps = 87/634 (13%) Query: 48 PGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL-------VPGGVADAAAAYKAAKAG- 99 PG LK VPG + G G +T G VPG D + + G Sbjct: 526 PGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGF 585 Query: 100 AGLGGVPGVGGLGVSAGAVVPQ-PGAGVKPGKV--PGVGLPGVYPGGVLPGAR-FPGVGV 155 GL G PG G G P PG PG++ PG+GLPG L G R FPG Sbjct: 586 PGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPG------LKGQRGFPGDAG 639 Query: 156 LPGVPTGAGVKPKA--PG-----------VGGAFAGIPGVGPFGGPQ--PGVPLGYPIKA 200 LPG P G A PG VGG G GGP+ PG+P P Sbjct: 640 LPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLP--GPPGP 697 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAG 259 G G+P G G GP G+ G AG+ G+P G +GP+ + A G Sbjct: 698 TGAKGLRGIPGFAGA-DGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPG 756 Query: 260 AAGVLPGVGGA----GVPG-VPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV 313 G LPG G G+PG V GA PG G AGV G P G+ + Sbjct: 757 PIG-LPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQG--M 813 Query: 314 PGGPGFGPGVVGVPG-AGVPGV-GVPGA-GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKA 370 PG PG G G+PG +G PG+ G PG G P PG P +PG+ E Sbjct: 814 PGMPGL-KGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGP-LGLPGIPGREGLPGDRGDP 871 Query: 371 AKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPE 430 GA VG+ G+ G G GF G G PG G G+ G+PG G+ G SP Sbjct: 872 GDTGAPGPVGMKGLS----GDRGDAGF-TGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPG 926 Query: 431 AQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 490 +PG+ PG + G G+ G+ PG + G PG Sbjct: 927 MDGFQG--------MPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGP 978 Query: 491 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 550 P + ++ G G GL +G G+ G+PGL +G+PG Sbjct: 979 PP----------VILPGMKDIKGEKG-DEGPMGLKGYLGAKGIQGMPGIPGL---SGIPG 1024 Query: 551 FGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 610 PG + K K VPG+ G G G G PG G + A +A + Sbjct: 1025 LPGRPGHI---KGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLY 1081 Query: 611 GLVGAAG-LGGLG-----VGGLGVPGVGGLGGIP 638 G +GA G G +G G G+ G G GIP Sbjct: 1082 GEIGATGDFGDIGDTINLPGRPGLKGERGTTGIP 1115 Score = 132 bits (333), Expect = 8e-31 Identities = 217/770 (28%), Positives = 272/770 (35%), Gaps = 169/770 (21%) Query: 28 GVPGAIPGGVPGGVFYPALGPGGKP-LKPVPGGLAGAGLG----AGLGAFPAVT-FPGAL 81 G+PG P G PG + P GP G P + +PG + GA G AG+ P + PG Sbjct: 747 GLPG--PDGSPGPIGLP--GPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDR 802 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ-----PGAGVKPGKVPGVGL 136 P G + + GL G PG+ G G P PGA PG+ +GL Sbjct: 803 GPPGFRGS----QGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGA---PGQEGPLGL 855 Query: 137 PGVYPGGVLPGARF-PGVGVLPGVP--------------TGAGVKPKAPGVGGAFAGIPG 181 PG+ LPG R PG PG TG P +PG G G+PG Sbjct: 856 PGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKG-IDGMPG 914 Query: 182 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-- 239 G + + P L G G P + G+ + +G G+ G AG+ G+ G Sbjct: 915 TPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGF-FGIPGLKGLAGEPGFKGSRGDP 973 Query: 240 --VGPQAAAAAAAK-----------AAAKFGAGAAGV--LPGVGG-AGVPGVPG------ 277 GP K K GA G+ +PG+ G +G+PG+PG Sbjct: 974 GPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIK 1033 Query: 278 ---------AIPGIGGIAGVGTPAAAAA----------AAAAAKAAKYGAAAGL------ 312 IPG+ G GV P A +A YG Sbjct: 1034 GVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDI 1093 Query: 313 -----VPGGPGFGP--GVVGVPGA-------GVPG-VGVPG-AGIPVVPGA-GIPG-AAV 354 +PG PG G G+PG G G +G PG G+ V G G+ G Sbjct: 1094 GDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGF 1153 Query: 355 PGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV-GVGGIPGVAGVPG 412 PG+ P + + G + G G P G GFPG G+ G+ G+PG G PG Sbjct: 1154 PGLTGPPGSQGELGRIGLPGGKGDDGWPGAP----GLPGFPGLRGIRGLHGLPGTKGFPG 1209 Query: 413 -----VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 467 + G PG G PG P G G APG PG +PG+ Sbjct: 1210 SPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQG-APGERGPPG---SPGLQ 1265 Query: 468 LAPGVGVAPGVGVAPGVGVAPGI----------GPGGVAAAAKSAAKVAAKAQLRAAAGL 517 PG+ + APG APGI GP G AA S Sbjct: 1266 GFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTK 1325 Query: 518 G-------------AGIPGLGVGVGVPGLGVGAGVPGLGVG-------AGVPGFGAVPGA 557 G G+PG G G G G VG G PGF PG Sbjct: 1326 GWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTG-AVGDRGPKGPKGDPGFPGAPGT 1384 Query: 558 LAAAKAAKYG---AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVG 614 + A A A PG +G G G G PG + GP A KA G Sbjct: 1385 VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKA------G 1438 Query: 615 AAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G GG+ VPG G G P + G RPG SP PG Sbjct: 1439 PQGRGGVS----AVPGFRGDEG-PIGHQGPIGQEGAPGRPG---SPGLPG 1480 Score = 118 bits (296), Expect = 2e-26 Identities = 211/720 (29%), Positives = 260/720 (36%), Gaps = 133/720 (18%) Query: 43 YPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGL 102 YP G G+P P G G GL FP + + K G Sbjct: 54 YPEKGGRGQPGPVGPQGYNGP---PGLQGFPGL------------------QGRKGDKGE 92 Query: 103 GGVPGVGGLGVSAGA--VVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARFPG 152 G PGV G GA V PGA PG PG G P PG G PG Sbjct: 93 RGAPGVTGPKGDVGARGVSGFPGADGIPGH-PGQGGPRGRPGYDGCNGTQGDSGPQGPPG 151 Query: 153 VGVLPGVPTGAGVKPKAPGVGGAFA-------------GIPGVGPFGGPQPGVPLGY--- 196 G P G K + G +A G PG+ F GP PG P G+ Sbjct: 152 SEGFTGPPGPQGPKGQK---GEPYALPKEERDRYRGEPGEPGLVGFQGP-PGRP-GHVGQ 206 Query: 197 --PIKAPKLPGGYGLPYTTGKLPY-GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAA 253 P+ AP PG G P G+ G G GV G G G P G+ A Sbjct: 207 MGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTG 266 Query: 254 AKF------GAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV----GTPAAAAAAAA-- 299 F G + PG+ G + G G + PG+ G G+ G+P + Sbjct: 267 VTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDG 326 Query: 300 -----AAKAAKYGAAAGLVPGGPGFGP---------GVVGVPGA-GVPGV-GVPG-AGIP 342 + K A PG P + P G G PGA G PG G PG G+P Sbjct: 327 YQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLP 386 Query: 343 VVPGAGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 398 PG I +PG + P+ A YG PG P G G PG Sbjct: 387 GPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPD 446 Query: 399 VGVGGIPGVAGVPGVGGVPGVGGVPG----VGISPEAQAAAAAKAAKYGLVPGVGVAPGV 454 + G+ G G G G+PG G G G + E + +A K GL PG+ PG Sbjct: 447 GFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIK-GL-PGL---PGP 501 Query: 455 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRA 513 G+ PG G G+ PG+ PG IG G A + + K + R Sbjct: 502 KGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGE-RG 560 Query: 514 AAGLGAGIPGLGVGVGVPGLGVGAGVPGL----GVG----AGVPGFGAVPGALAA-AKAA 564 G+ G+PG+ G PG G PGL G G G PG+ +PG + Sbjct: 561 QPGV-PGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMG 619 Query: 565 KYGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAA-----------AAAAKAAAKAAQF 610 G +PG+ G G G G+PG G +G GPA A +A Q Sbjct: 620 PPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQP 679 Query: 611 GLVGA-AGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFGLSPIFPG 664 G +G GL GL G G G GL GIP A A G A R GF P F G Sbjct: 680 GCIGGPKGLPGL-PGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIG 738 Score = 98.2 bits (243), Expect = 2e-20 Identities = 142/479 (29%), Positives = 174/479 (36%), Gaps = 90/479 (18%) Query: 23 PSRPGGVPGA-----IPGGVPGGVFYPALG--PGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P RPG + G +PG +PG +P + PG G G G + + Sbjct: 1026 PGRPGHIKGVKGDIGVPG-IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEI 1084 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV--VPQPG----AGVK-- 127 G G K G G+PG+ G G + PG GV+ Sbjct: 1085 GATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGP 1144 Query: 128 PGKVPGVGLPGVY--PGGV-------LPGAR----FPGVGVLPGVPTGAGVKPK--APGV 172 PG G PG+ PG LPG + +PG LPG P G++ PG Sbjct: 1145 PGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGT 1204 Query: 173 GGAFAGIPGVGPFGGPQ-PGVP--LGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGG--- 224 G F G PG G P PG P G P +A LPG G+P G P GP G Sbjct: 1205 KG-FPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPG 1263 Query: 225 ------------VAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGV--LPG 266 ++GA G G P G+ GP +AA +K G G PG Sbjct: 1264 LQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPG 1323 Query: 267 VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 326 G P PG+ G+ G P GA P GP PG G Sbjct: 1324 TKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMG--NTGPTGAVGDRGPKGPKGDPGFPGA 1381 Query: 327 PGAGVPGVGVPG-AGIP----VVPGA-------GIPGAAVPGVVSPEAAAKAAAKAAKYG 374 PG VG PG AGIP V PG G PGA PG + P+ + G Sbjct: 1382 PGT----VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGA--PGEMGPQGPP------GEPG 1429 Query: 375 ARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 428 R G G G G PGF +G G G G PG G PG+ G+PG +S Sbjct: 1430 FRGAPGKAGPQGRG-GVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVS 1487 Score = 58.2 bits (139), Expect = 3e-08 Identities = 93/301 (30%), Positives = 108/301 (35%), Gaps = 73/301 (24%) Query: 23 PSRPG--GVPG---AIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 77 P PG G PG +PG P GV PG K + PG G GL FP +T Sbjct: 1222 PGPPGERGDPGEANTLPG--PVGV------PGQKGDQGAPGERGPPG-SPGLQGFPGIT- 1271 Query: 78 PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLP 137 P + + G D G PG+ GL G P PG+ PG G P Sbjct: 1272 PPSNISGAPGDK--------------GAPGIFGLKGYRGPPGP-PGSAALPGSKGDTGNP 1316 Query: 138 GV--------YPGGVLPGARFPGVGVLPGV--------------PTGA--GVKPKAPGVG 173 G + G P R PGV LPG PTGA PK P Sbjct: 1317 GAPGTPGTKGWAGDSGPQGR-PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGD 1375 Query: 174 GAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKA 232 F G PG VG PG+ G P K PG G G P G G G G+ Sbjct: 1376 PGFPGAPGTVGA-----PGIA-GIPQKIAVQPGTVGPQGRRGP-PGAPGEMGPQGPPGEP 1428 Query: 233 GYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGV--------LPG-VGGAGVPGVPGAIPGI 282 G+ G GPQ +A + G G PG G G+PG+PG I Sbjct: 1429 GFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSI 1488 Query: 283 G 283 G Sbjct: 1489 G 1489 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 157 bits (398), Expect = 2e-38 Identities = 244/775 (31%), Positives = 275/775 (35%), Gaps = 200/775 (25%) Query: 36 GVPGGVFYPALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GAL 81 G PG P GP G P P P GL G AG GA LG P G Sbjct: 153 GEPGTPGNP--GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPR 209 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY- 140 P G A A + + G G PGV G G PG KPG G PG Sbjct: 210 GPPGPAGAPGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAG 264 Query: 141 ---PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-------GPFGGP 188 P G FPG LPGV G PG+ GA AG PGV G G P Sbjct: 265 ERGPPGPQGARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGENGSP 320 Query: 189 QPGVPLGYPIKAPKL--------------PGGYGLPYTTGKLPYGYGPG--GVAGAAGKA 232 P P G P + + PG G P G P G GPG G GA G+A Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG--PAG-GPGFPGAPGAKGEA 377 Query: 233 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--------LPGV-GGAGVPGVPGA----- 278 G PTG GP+ A + G AG +PG G AG PG+ GA Sbjct: 378 G-PTGAR-GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 435 Query: 279 ---------------------IPGIGGIAG----------VGTPAAAAAAAAAAKAAKYG 307 PGI G G G A A K G Sbjct: 436 PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG 495 Query: 308 AAAGLVPGGPGFGPGVVGVPG-AGVPG-------VGVPGA-------------GIPVVPG 346 G+ P GP PG G PG G PG G PG G P PG Sbjct: 496 EPGGVGPIGP---PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 552 Query: 347 -AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPG----VGVGGIPTYGVGAGGFPGF 397 G+PGA PG P+ + + G RPG G G P G GFPG Sbjct: 553 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG-RPGPPGPQGARGQP----GVMGFPG- 606 Query: 398 GVGVGGIPGVAGVPGVGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGLVPGVGVAP 452 G G PG AG G+ G PG+ G+PG P A A + + G AP Sbjct: 607 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG-------AP 659 Query: 453 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQL 511 G G+ PG PG G PG PG APG +GP G A+ L Sbjct: 660 GPSGFQGLPGPPG---PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG-L 715 Query: 512 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA------- 564 + GL G PG G G AG PG G PG +PG AA A Sbjct: 716 QGPRGL-PGTPGTD---GPKGASGPAGPPG---AQGPPGLQGMPGERGAAGIAGPKGDRG 768 Query: 565 ----KYGAAVPGVLGGLGALGGVGIPG--------GVVG-AGPAAAAAAAKAAAKAAQFG 611 K PG GG G G +G PG G VG GPA +A A A + + G Sbjct: 769 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 828 Query: 612 LVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G AG G G G PG G G +A + G A PG P P GA Sbjct: 829 PPGPAGFAG-PPGADGQPGAKGEQG-------EAGQKGDAGAPG----PQGPSGA 871 Score = 155 bits (392), Expect = 1e-37 Identities = 213/679 (31%), Positives = 243/679 (35%), Gaps = 93/679 (13%) Query: 28 GVPGAIPGGVPGGVFYP--ALGPGGKPLKPVPGGLAGAGLGAGLGAFP------------ 73 G PGA P G P A GP G+P P G AGA G P Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 428 Query: 74 -AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKP 128 A FPG P G A K G+ G G G G PQ PG + Sbjct: 429 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 488 Query: 129 GKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFG 186 GK G P GV P G PG R PG PG AG K APG G +G+ G Sbjct: 489 GKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPK-GAPGERGP-SGLAGPKGAN 545 Query: 187 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAGAAGKAGYPTGTGVGPQA 244 G PG P P LPG GL G P G GP G G G+ G P GPQ Sbjct: 546 G-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP-----GPQG 594 Query: 245 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAK 302 A GA G G G+PG PG +PG G G P A A + Sbjct: 595 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP--PGPAGPAGE 652 Query: 303 AAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPVVPGAGIPG-AAVPGVVS 359 + GA PG GF PG G PG G G PG G+PG A PG+V Sbjct: 653 RGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG-------DQGVPGEAGAPGLVG 696 Query: 360 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV 419 P + GA+ G G+P G P G G PG G PG+ G+PG Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGE 754 Query: 420 GGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 471 G G+ + + A K GL +G PG A G G PG Sbjct: 755 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAGANGEKGEVG---PPG 810 Query: 472 VGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVG 529 + G APG G GP G A + + AK + A G AG PG G Sbjct: 811 PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870 Query: 530 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 589 PG GV G G G PGA PG G +G G G PG Sbjct: 871 APGPQGPTGVTG---PKGARGAQGPPGA----------TGFPGAAGRVGPPGSNGNPGPP 917 Query: 590 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGI--PPAAAAKA 645 GP+ A + G G GL G G G PG G G PP A Sbjct: 918 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 977 Query: 646 AKYGVAARPGFGLSPIFPG 664 + G+ PG FPG Sbjct: 978 GQRGIVGLPGQRGERGFPG 996 Score = 145 bits (367), Expect = 9e-35 Identities = 223/677 (32%), Positives = 251/677 (37%), Gaps = 108/677 (15%) Query: 26 PGGV-PGAIPG--GVPGGVFYPA----LGPGGKPLKPVPGGLAGA-GLGAGLGAFPAVTF 77 PGGV P PG G PG +P GP G P + P GLAG G G Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556 Query: 78 PGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 135 PGA + G DA K +GA G G PG G + G QPG PG G Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG----QPGVMGFPGPKGANG 612 Query: 136 LPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPG 191 PG LPGA PG+ LPG TGA P G G G PG F G PG Sbjct: 613 EPGKAGEKGLPGA--PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG-LPG 669 Query: 192 VPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAA 250 P G P + K PG G+P G P GP G G G+ G P G+ GP+ Sbjct: 670 PP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726 Query: 251 KAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAK 305 K +G AG PG G G+PG GA GI G G G A K Sbjct: 727 TDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGEKGPEGAPGKDGG 784 Query: 306 YGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG-AGIPVVPGA-GI 349 G + P GP PG G GA G PG G PG AG PGA G Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 844 Query: 350 PG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 396 PG A PG P A G + G G P GA GFPG Sbjct: 845 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----GATGFPG 900 Query: 397 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-----VPGVGVA 451 G G PG G PG G PG G G + +A + GL PG Sbjct: 901 -AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGLQGPAGPPGEKGE 958 Query: 452 PGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 510 PG G PG GLA G+ G+ G PG+ PG K A A+ + Sbjct: 959 PGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEPGKQGAPGASGDR 1016 Query: 511 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G PG VG PGL AG PG G PG PG A A V Sbjct: 1017 ---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRDGA-------AGV 1054 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV------ 623 G G GA+G G PG GPA +A G +G +G G G+ Sbjct: 1055 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114 Query: 624 ----GGLGVPGVGGLGG 636 G G PG GL G Sbjct: 1115 RGDKGEAGEPGERGLKG 1131 Score = 142 bits (357), Expect = 1e-33 Identities = 221/705 (31%), Positives = 256/705 (36%), Gaps = 120/705 (17%) Query: 23 PSRPG--GVPGAI-----PGGV-PGGVFYPALGPG--GKPLKPVPGGLAGAGLGAGLGAF 72 P RPG G+PGA PG P G P+ PG G+P P P G G G+ F Sbjct: 548 PGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ---PGVMGF 604 Query: 73 PAVT-------------FPGAL----VPGGVADAAAAYKAAKAGA----GLGGVPGVGGL 111 P PGA +PG + AA AG G G PG G Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664 Query: 112 GVSAGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-FPGVGVLPG 158 G P PG G KPG VPG G PG+ +PG PGA+ G LPG Sbjct: 665 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 723 Query: 159 VPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGYPIKAPKLP 204 P G K + PG G G+PG GP G + V P AP Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKGPEGAPGKD 782 Query: 205 GGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAK 255 GG GL G P G GP G AG+AG G P G GP A A A Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGAD 842 Query: 256 FGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA 310 GA G G G G PG PG G GV P A A A + AA Sbjct: 843 GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 902 Query: 311 GLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPGA-AVPGVV 358 G V P G PG G PG G G G PG AG P + G AG PG PG Sbjct: 903 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962 Query: 359 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 418 P A G R G+ G+P G GFPG +PG +G PG G PG Sbjct: 963 GPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGEPGKQGAPG 1011 Query: 419 VGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP 476 G G + P A + + G +PG PG A GV G A Sbjct: 1012 ASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKGDRGETGAV 1064 Query: 477 GVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGV 535 G APG +PG P G + A+ + + GA GI G G G Sbjct: 1065 GAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAG 1122 Query: 536 GAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGALGGVGIPG 587 G GL G G +PG A+ A G PG +G G G GIPG Sbjct: 1123 EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPG 1182 Query: 588 GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 + GP + A G G G G G+ G+G Sbjct: 1183 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1227 Score = 128 bits (321), Expect = 2e-29 Identities = 185/577 (32%), Positives = 207/577 (35%), Gaps = 58/577 (10%) Query: 94 KAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGV 153 K A G G PG G PG PG GL G + + G Sbjct: 143 KGAPGPRGRDGEPGTPG----------NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192 Query: 154 GVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP-----QPGV--PLGYPIKAPKLPGG 206 G GV G + P P AG PG F G +PGV P+G P P PG Sbjct: 193 GAQLGVMQGP-MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGK 250 Query: 207 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLP 265 G GK P G G G G G+P G+ G + AK AGA GV Sbjct: 251 PGDDGEAGK-PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309 Query: 266 GVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 324 G G G PG + G G+ G G A AA A + G A P GP GPG Sbjct: 310 ESGSPGENGSPGPM-GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFP 368 Query: 325 GVPG----AGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 379 G PG AG G G GA P G PG PG P A+ GA+ Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGP----RGEPG--TPGSPGPAGASGNPGTDGIPGAKGSA 422 Query: 380 GVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAA 437 G GI GA GFPG G G G G G G PG+ G G P+ + A Sbjct: 423 GAPGI----AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ-GPKGEPGPAG 477 Query: 438 KAAKYGLVPGVGVAPGVGVAPGVGV--APGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGG 494 G G G GVG PG APG PG G APG GP G Sbjct: 478 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 537 Query: 495 VAA--AAKSAAKVAAKAQLRAAAGL-----GAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 547 +A A + L A GL AG G G PG G PG G Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 597 Query: 548 VPGFGAVPGALAA----AKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 602 PG PG A KA + G PG+ G G G G G AGPA Sbjct: 598 QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 657 Query: 603 AAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGI 637 A + GL G G G G G GVPG G G+ Sbjct: 658 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694 Score = 122 bits (306), Expect = 1e-27 Identities = 159/504 (31%), Positives = 180/504 (35%), Gaps = 49/504 (9%) Query: 200 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY------PTGTGVGPQAAAAAAAKAA 253 +P++P G P L G G G G+ G P G GPQ A Sbjct: 77 SPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPP-GPQGPAGEQGPRG 135 Query: 254 AKFGAGAAGVLPGVGGA----GVPGVPG--AIPGIGGIAGVGTPAAAAAAAA---AAKAA 304 + G G PG G G PG PG PG G G+G AA A A A Sbjct: 136 DRGDKGEKGA-PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 194 Query: 305 KYGAAAG-LVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVV 358 + G G + P GP PG G PG G PG G PG P+ P G PG PG Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGKP 251 Query: 359 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 418 + A KA + G G G P G G PG G G PG+ G G G PG Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFP----GTPGLPGV-KGHRGYPGLDGAKGEAGAPG 306 Query: 419 V---GGVPGVGISPEAQAAAAAKAAKYGLVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVG 473 V G PG SP + P G A G PG PG VG A G G Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366 Query: 474 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 532 G G GP G + A+ G GIPG G PG Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426 Query: 533 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVV 590 + AG PG G PG G L K PG+ G G G G PG G Sbjct: 427 I---AGAPGFPGPRGPPGPQGATGPL----GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479 Query: 591 GA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYG 649 GA GPA A + G +G G G G G PG GL G P A + G Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERG-APGNRGFPGQDGLAG-PKGAPGERGPSG 537 Query: 650 VAARPGFGLSPIFPGGACLGKACG 673 +A G P PG L A G Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARG 561 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 157 bits (398), Expect = 2e-38 Identities = 244/775 (31%), Positives = 275/775 (35%), Gaps = 200/775 (25%) Query: 36 GVPGGVFYPALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GAL 81 G PG P GP G P P P GL G AG GA LG P G Sbjct: 84 GEPGTPGNP--GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPR 140 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY- 140 P G A A + + G G PGV G G PG KPG G PG Sbjct: 141 GPPGPAGAPGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAG 195 Query: 141 ---PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-------GPFGGP 188 P G FPG LPGV G PG+ GA AG PGV G G P Sbjct: 196 ERGPPGPQGARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGENGSP 251 Query: 189 QPGVPLGYPIKAPKL--------------PGGYGLPYTTGKLPYGYGPG--GVAGAAGKA 232 P P G P + + PG G P G P G GPG G GA G+A Sbjct: 252 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVG--PAG-GPGFPGAPGAKGEA 308 Query: 233 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--------LPGV-GGAGVPGVPGA----- 278 G PTG GP+ A + G AG +PG G AG PG+ GA Sbjct: 309 G-PTGAR-GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 366 Query: 279 ---------------------IPGIGGIAG----------VGTPAAAAAAAAAAKAAKYG 307 PGI G G G A A K G Sbjct: 367 PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG 426 Query: 308 AAAGLVPGGPGFGPGVVGVPG-AGVPG-------VGVPGA-------------GIPVVPG 346 G+ P GP PG G PG G PG G PG G P PG Sbjct: 427 EPGGVGPIGP---PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 483 Query: 347 -AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPG----VGVGGIPTYGVGAGGFPGF 397 G+PGA PG P+ + + G RPG G G P G GFPG Sbjct: 484 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG-RPGPPGPQGARGQP----GVMGFPG- 537 Query: 398 GVGVGGIPGVAGVPGVGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGLVPGVGVAP 452 G G PG AG G+ G PG+ G+PG P A A + + G AP Sbjct: 538 PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG-------AP 590 Query: 453 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQL 511 G G+ PG PG G PG PG APG +GP G A+ L Sbjct: 591 GPSGFQGLPGPPG---PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG-L 646 Query: 512 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA------- 564 + GL G PG G G AG PG G PG +PG AA A Sbjct: 647 QGPRGL-PGTPGTD---GPKGASGPAGPPG---AQGPPGLQGMPGERGAAGIAGPKGDRG 699 Query: 565 ----KYGAAVPGVLGGLGALGGVGIPG--------GVVG-AGPAAAAAAAKAAAKAAQFG 611 K PG GG G G +G PG G VG GPA +A A A + + G Sbjct: 700 DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 759 Query: 612 LVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G AG G G G PG G G +A + G A PG P P GA Sbjct: 760 PPGPAGFAG-PPGADGQPGAKGEQG-------EAGQKGDAGAPG----PQGPSGA 802 Score = 155 bits (392), Expect = 1e-37 Identities = 213/679 (31%), Positives = 243/679 (35%), Gaps = 93/679 (13%) Query: 28 GVPGAIPGGVPGGVFYP--ALGPGGKPLKPVPGGLAGAGLGAGLGAFP------------ 73 G PGA P G P A GP G+P P G AGA G P Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359 Query: 74 -AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKP 128 A FPG P G A K G+ G G G G PQ PG + Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419 Query: 129 GKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFG 186 GK G P GV P G PG R PG PG AG K APG G +G+ G Sbjct: 420 GKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPK-GAPGERGP-SGLAGPKGAN 476 Query: 187 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAGAAGKAGYPTGTGVGPQA 244 G PG P P LPG GL G P G GP G G G+ G P GPQ Sbjct: 477 G-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP-----GPQG 525 Query: 245 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAK 302 A GA G G G+PG PG +PG G G P A A + Sbjct: 526 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP--PGPAGPAGE 583 Query: 303 AAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPVVPGAGIPG-AAVPGVVS 359 + GA PG GF PG G PG G G PG G+PG A PG+V Sbjct: 584 RGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG-------DQGVPGEAGAPGLVG 627 Query: 360 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV 419 P + GA+ G G+P G P G G PG G PG+ G+PG Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGE 685 Query: 420 GGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 471 G G+ + + A K GL +G PG A G G PG Sbjct: 686 RGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAGANGEKGEVG---PPG 741 Query: 472 VGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVG 529 + G APG G GP G A + + AK + A G AG PG G Sbjct: 742 PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801 Query: 530 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 589 PG GV G G G PGA PG G +G G G PG Sbjct: 802 APGPQGPTGVTG---PKGARGAQGPPGA----------TGFPGAAGRVGPPGSNGNPGPP 848 Query: 590 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGI--PPAAAAKA 645 GP+ A + G G GL G G G PG G G PP A Sbjct: 849 GPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLA 908 Query: 646 AKYGVAARPGFGLSPIFPG 664 + G+ PG FPG Sbjct: 909 GQRGIVGLPGQRGERGFPG 927 Score = 145 bits (367), Expect = 9e-35 Identities = 223/677 (32%), Positives = 251/677 (37%), Gaps = 108/677 (15%) Query: 26 PGGV-PGAIPG--GVPGGVFYPA----LGPGGKPLKPVPGGLAGA-GLGAGLGAFPAVTF 77 PGGV P PG G PG +P GP G P + P GLAG G G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487 Query: 78 PGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 135 PGA + G DA K +GA G G PG G + G QPG PG G Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG----QPGVMGFPGPKGANG 543 Query: 136 LPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPG 191 PG LPGA PG+ LPG TGA P G G G PG F G PG Sbjct: 544 EPGKAGEKGLPGA--PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQG-LPG 600 Query: 192 VPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAA 250 P G P + K PG G+P G P GP G G G+ G P G+ GP+ Sbjct: 601 PP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657 Query: 251 KAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAK 305 K +G AG PG G G+PG GA GI G G G A K Sbjct: 658 TDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGEKGPEGAPGKDGG 715 Query: 306 YGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG-AGIPVVPGA-GI 349 G + P GP PG G GA G PG G PG AG PGA G Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775 Query: 350 PG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 396 PG A PG P A G + G G P GA GFPG Sbjct: 776 PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----GATGFPG 831 Query: 397 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-----VPGVGVA 451 G G PG G PG G PG G G + +A + GL PG Sbjct: 832 -AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGLQGPAGPPGEKGE 889 Query: 452 PGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 510 PG G PG GLA G+ G+ G PG+ PG K A A+ + Sbjct: 890 PGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEPGKQGAPGASGDR 947 Query: 511 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G PG VG PGL AG PG G PG PG A A V Sbjct: 948 ---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRDGA-------AGV 985 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV------ 623 G G GA+G G PG GPA +A G +G +G G G+ Sbjct: 986 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045 Query: 624 ----GGLGVPGVGGLGG 636 G G PG GL G Sbjct: 1046 RGDKGEAGEPGERGLKG 1062 Score = 142 bits (357), Expect = 1e-33 Identities = 221/705 (31%), Positives = 256/705 (36%), Gaps = 120/705 (17%) Query: 23 PSRPG--GVPGAI-----PGGV-PGGVFYPALGPG--GKPLKPVPGGLAGAGLGAGLGAF 72 P RPG G+PGA PG P G P+ PG G+P P P G G G+ F Sbjct: 479 PGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ---PGVMGF 535 Query: 73 PAVT-------------FPGAL----VPGGVADAAAAYKAAKAGA----GLGGVPGVGGL 111 P PGA +PG + AA AG G G PG G Sbjct: 536 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595 Query: 112 GVSAGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-FPGVGVLPG 158 G P PG G KPG VPG G PG+ +PG PGA+ G LPG Sbjct: 596 QGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 654 Query: 159 VPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGYPIKAPKLP 204 P G K + PG G G+PG GP G + V P AP Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKGPEGAPGKD 713 Query: 205 GGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAK 255 GG GL G P G GP G AG+AG G P G GP A A A Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGAD 773 Query: 256 FGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA 310 GA G G G G PG PG G GV P A A A + AA Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 833 Query: 311 GLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPGA-AVPGVV 358 G V P G PG G PG G G G PG AG P + G AG PG PG Sbjct: 834 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893 Query: 359 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 418 P A G R G+ G+P G GFPG +PG +G PG G PG Sbjct: 894 GPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGEPGKQGAPG 942 Query: 419 VGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP 476 G G + P A + + G +PG PG A GV G A Sbjct: 943 ASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKGDRGETGAV 995 Query: 477 GVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGV 535 G APG +PG P G + A+ + + GA GI G G G Sbjct: 996 GAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAG 1053 Query: 536 GAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGALGGVGIPG 587 G GL G G +PG A+ A G PG +G G G GIPG Sbjct: 1054 EPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPG 1113 Query: 588 GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 + GP + A G G G G G+ G+G Sbjct: 1114 PIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1158 Score = 128 bits (321), Expect = 2e-29 Identities = 185/577 (32%), Positives = 207/577 (35%), Gaps = 58/577 (10%) Query: 94 KAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGV 153 K A G G PG G PG PG GL G + + G Sbjct: 74 KGAPGPRGRDGEPGTPG----------NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 123 Query: 154 GVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP-----QPGV--PLGYPIKAPKLPGG 206 G GV G + P P AG PG F G +PGV P+G P P PG Sbjct: 124 GAQLGVMQGP-MGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMG-PRGPPGPPGK 181 Query: 207 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLP 265 G GK P G G G G G+P G+ G + AK AGA GV Sbjct: 182 PGDDGEAGK-PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240 Query: 266 GVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 324 G G G PG + G G+ G G A AA A + G A P GP GPG Sbjct: 241 ESGSPGENGSPGPM-GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFP 299 Query: 325 GVPG----AGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 379 G PG AG G G GA P G PG PG P A+ GA+ Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGP----RGEPG--TPGSPGPAGASGNPGTDGIPGAKGSA 353 Query: 380 GVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAA 437 G GI GA GFPG G G G G G G PG+ G G P+ + A Sbjct: 354 GAPGI----AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ-GPKGEPGPAG 408 Query: 438 KAAKYGLVPGVGVAPGVGVAPGVGV--APGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGG 494 G G G GVG PG APG PG G APG GP G Sbjct: 409 PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSG 468 Query: 495 VAA--AAKSAAKVAAKAQLRAAAGL-----GAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 547 +A A + L A GL AG G G PG G PG G Sbjct: 469 LAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG 528 Query: 548 VPGFGAVPGALAA----AKAAKYG-AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 602 PG PG A KA + G PG+ G G G G G AGPA Sbjct: 529 QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG 588 Query: 603 AAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGI 637 A + GL G G G G G GVPG G G+ Sbjct: 589 APGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625 Score = 120 bits (302), Expect = 3e-27 Identities = 152/476 (31%), Positives = 170/476 (35%), Gaps = 47/476 (9%) Query: 222 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPG 277 PG + G G P GPQ A + G G PG G G PG PG Sbjct: 40 PGDIKDIVGPKGPP-----GPQGPAGEQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGNPG 93 Query: 278 --AIPGIGGIAGVGTPAAAAAAAA---AAKAAKYGAAAG-LVPGGPGFGPGVVGVPG--- 328 PG G G+G AA A A A+ G G + P GP PG G PG Sbjct: 94 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 153 Query: 329 -AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386 G PG G PG P+ P G PG PG + A KA + G G G P Sbjct: 154 FQGNPGEPGEPGVSGPMGP-RGPPGP--PGKPGDDGEAGKPGKAGERGPPGPQGARGFP- 209 Query: 387 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAAAAAKAAKYG 443 G G PG G G PG+ G G G PGV G PG SP + Sbjct: 210 ---GTPGLPGV-KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265 Query: 444 LVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 501 P G A G PG PG VG A G G G G GP G Sbjct: 266 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325 Query: 502 AAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 560 + A+ G GIPG G PG+ AG PG G PG G L Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI---AGAPGFPGPRGPPGPQGATGPL-- 380 Query: 561 AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAG 617 K PG+ G G G G PG G GA GPA A + G +G G Sbjct: 381 --GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 438 Query: 618 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 673 G G G PG GL G P A + G+A G P PG L A G Sbjct: 439 ERG-APGNRGFPGQDGLAG-PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 152 bits (384), Expect = 1e-36 Identities = 224/723 (30%), Positives = 257/723 (35%), Gaps = 145/723 (20%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGV 86 G+PGAI G PG A GP G P P G AG G G+ P G+ Sbjct: 417 GLPGAIGTDGTPG-----AKGPTGSPGTSGPPGSAGPPGSPGP--------QGSTGPQGI 463 Query: 87 ADAAA--AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK-PGKVPG-VGLPGVYPG 142 K AG G PG G+ G + P G + P PG VG PG Sbjct: 464 RGQPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGPPGEEGKRGPRGDPGTVGPPGPVGE 520 Query: 143 GVLPGAR-FPGVGVLPGVPTGA----------GVK--------PKAPGVGGA--FAGIPG 181 PG R FPG LPG P GA G K P PG+ GA G PG Sbjct: 521 RGAPGNRGFPGSDGLPG-PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG 579 Query: 182 V-------GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGA 228 V GP G P +PG P I+ PG GLP G P G G AG Sbjct: 580 VQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ--PGSMGLPGPKGSSGDPGKPGEAGNAGV 637 Query: 229 AGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVL-----------PGVGGA----GV 272 G+ G P G VGP A + G G PG GG GV Sbjct: 638 PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697 Query: 273 PGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGV 331 PG PGA+ +G G P + G A G P GP PG G PG G Sbjct: 698 PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGP 757 Query: 332 PGV-GVPG-AGIPVVPG----------------AGIPGA-AVPGVVSPEAAAKAAAKAAK 372 PG+ G+PG GI PG AG GA +PG + P A + + Sbjct: 758 PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817 Query: 373 YGARPGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 G R VG G PT GA GF G G G PGV G PG G G G Sbjct: 818 PGPRGLVGPPGSRGNPGSRGENGPT---GAVGFAG-PQGPDGQPGVKGEPGEPGQKGDAG 873 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGV 480 PG P+ A + G VPG+ G PG PG G G A G Sbjct: 874 SPG----PQGLAGSPGPHGPNG-VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP 928 Query: 481 APGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------------------AGI 521 A +G GP G+ S +V + G G AG Sbjct: 929 AGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGT 988 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 581 G VG+PG G+PGL AG PG GA PG +G G+ G Sbjct: 989 TGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATG-------DKGPPGPVGPPGSNG 1041 Query: 582 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 641 VG PG AG A + G G AGL G G PG G G P A Sbjct: 1042 PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL----PGSQGAPGTPGPVGAPGDA 1097 Query: 642 AAK 644 + Sbjct: 1098 GQR 1100 Score = 138 bits (347), Expect = 2e-32 Identities = 227/756 (30%), Positives = 272/756 (35%), Gaps = 165/756 (21%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL--------AGAGLGAGLGAFPA 74 P P G+ G GVPG P GP G P P P GL AG +GLG+ Sbjct: 154 PRGPQGIDGE--PGVPGQPGAP--GPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVG 209 Query: 75 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG-------VGGLGVSAGAVVP--QPGAG 125 + PG++ P G + + GAG G PG +G +G S G P +PG Sbjct: 210 L-MPGSVGPVGPR-GPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG-SRGPEGPPGKPGED 266 Query: 126 VKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVK----PKAP-GVGGAFAGI 179 +PG+ G PG PGAR FPG LPG+ G K PK G G+ Sbjct: 267 GEPGRN---GNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEA 323 Query: 180 PGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTG 237 GP G P P G P + +L G G P G +P GP G G G +G+P Sbjct: 324 GPTGPMGAMGPLGPRGMPGERGRL-GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382 Query: 238 TGVGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVP------GVPGA-----IPGIGGI 285 G+ +A A G PG VG G+P G PGA PG G Sbjct: 383 PGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGP 442 Query: 286 AG-------------------------VGTPAAAAAAAAAAKAAKYGAAAGLVP------ 314 G G P A + +G + P Sbjct: 443 PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGK 502 Query: 315 GGPGFGPGVVGVPG----AGVPG-VGVPGA-GIPVVPGA--------------------- 347 GP PG VG PG G PG G PG+ G+P GA Sbjct: 503 RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGR 562 Query: 348 ----GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPG----VGVGGIPTYGVGAGGFP 395 G+PGA PGV PE + G RPG +G+ G P G+ G P Sbjct: 563 PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDG-RPGPPGSIGIRGQP----GSMGLP 617 Query: 396 GFGVGVGGIPGVAGVPGVGGVPGVGGVPG----VGIS-PEAQAAAAAKAAKYGL------ 444 G G G PG G G GVPG G PG VG S P A + + G Sbjct: 618 G-PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF 676 Query: 445 --VPGVGVAPGVGVAPGVGVAPGVGLA------------PGVGVAPGVGVAPG-VGVAPG 489 +PG PG G PG PG A PG PG+ PG G+A G Sbjct: 677 QGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGG 736 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL---GVGAGVPGLGVGA 546 GP G K + + GL G+PG G PG G G G A Sbjct: 737 HGPDG----PKGSPGPSGTPGDTGPPGL-QGMPGERGIAGTPGPKGDRGGIGEKGAEGTA 791 Query: 547 GVPGFGAVPGALA----AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 602 G G +PG L A + G PG G +G G G PG GP A A Sbjct: 792 GNDGARGLPGPLGPPGPAGPTGEKGE--PGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849 Query: 603 AAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 638 Q G+ G G G G G PG GL G P Sbjct: 850 PQGPDGQPGVKGEPGEPG-QKGDAGSPGPQGLAGSP 884 Score = 128 bits (321), Expect = 2e-29 Identities = 216/707 (30%), Positives = 252/707 (35%), Gaps = 137/707 (19%) Query: 23 PSRPG--GVPGA--IPG--GVPG--GVFYPALGPG--GKPLKPVPGGLAGAGLGAGLGAF 72 P RPG G+PGA + G GV G G P PG G+P P G+ G GL Sbjct: 560 PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL--- 616 Query: 73 PAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 131 PG G D +A AG G G PG G +G V P PG + G+ Sbjct: 617 -----PGP--KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP-PGLAGERGEQ 668 Query: 132 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGPQP 190 G PG P G F G+ PG P G G KP GV G PG VGP G P Sbjct: 669 ---GPPG--PTG------FQGLPGPPG-PPGEGGKPGDQGVPGD----PGAVGPLG---P 709 Query: 191 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-------GPQ 243 G P + + PG GLP G + G+GP G G+ G +G P TG G + Sbjct: 710 RGERGNPGERGE-PGITGLPGEKG-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGER 767 Query: 244 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG----------VGTP 291 A + G G G G G G+PG + PG G G VG P Sbjct: 768 GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827 Query: 292 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----------------AGVPGV- 334 + + + GA P GP PGV G PG AG PG Sbjct: 828 GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPH 887 Query: 335 ---GVPGA----GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386 GVPG G PGA G PG+A G V P A A A G G G P Sbjct: 888 GPNGVPGLKGGRGTQGPPGATGFPGSA--GRVGPPGPAGAPGPAGPLGEP---GKEGPP- 941 Query: 387 YGVGAGGFPGFGVGVG--GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 444 G G PG VG G G G PG G PG G PG P+ A + G+ Sbjct: 942 ---GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG----PDGPPGPAGTTGQRGI 994 Query: 445 V--PGVGVAPGVGVAPGVGVAPG----VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAA 498 V PG G+ PG PG G G VG G GP G A Sbjct: 995 VGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054 Query: 499 AKSAAKVAAKAQLR-----AAAGL--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 551 + + A + AGL G PG VG PG G PG G PG Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114 Query: 552 GA---VPGALAA-AKAAKYG----------------AAVPGVLGGLGALGGVGIPGGVVG 591 +PG +G +PG G G G GIPG Sbjct: 1115 AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGP 1174 Query: 592 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 638 GP + G +G G+ G VG G G G G P Sbjct: 1175 RGPPGPVGPSGKEGNPGPLGPIGPPGVRG-SVGEAGPEGPPGEPGPP 1220 Score = 122 bits (306), Expect = 1e-27 Identities = 196/610 (32%), Positives = 225/610 (36%), Gaps = 57/610 (9%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 PS P G PG G G P GP G P P G G G G P PGA+ Sbjct: 652 PSGPVGPPGL--AGERGEQGPP--GPTGFQGLPGPPGPPGEGGKPGDQGVPGD--PGAVG 705 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVY 140 P G + G+ G+PG G+ G P+ PG PG GL G Sbjct: 706 PLGPR-GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQG-- 762 Query: 141 PGGVLPGARFPGVGVLPGVPTG--AGVKPK-APGVGG--AFAGIPGVGPFGGPQPGVPLG 195 +PG R G+ PG P G G+ K A G G G+PG P G P P P G Sbjct: 763 ----MPGER--GIAGTPG-PKGDRGGIGEKGAEGTAGNDGARGLPG--PLGPPGPAGPTG 813 Query: 196 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 255 + P G G P + G P G G GA G AG P G G + K Sbjct: 814 EKGE-PGPRGLVGPPGSRGN-PGSRGENGPTGAVGFAG-PQGPD-GQPGVKGEPGEPGQK 869 Query: 256 FGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVP 314 AG+ G G+ G+ P P +PG+ G G G P A +A + G A P Sbjct: 870 GDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP 928 Query: 315 GGPGFGPGVVGVPGA-GVPG----VGVPG-AGIPVVPG-AGIPGA-AVPGVVSPEAAAKA 366 GP PG G PG G PG VG G AG P PG G PG PG P A Sbjct: 929 AGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGT 988 Query: 367 AAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVG 426 + G G G+P G G PG VG G G G PG G PG G G Sbjct: 989 TGQRGIVGMPGQRGERGMPGLP-GPAGTPG-KVGPTGATGDKGPPGPVGPPGSNGPVGEP 1046 Query: 427 ISPEAQAAAAAKAAKYGLVPGVGVA--PGVGVAPGVGVAPGVGLAPGVGVAPG-VGVAPG 483 PE A + G V G PG PG APG PG APG G Sbjct: 1047 -GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGT---PGPVGAPGDAGQRGD 1102 Query: 484 VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGL 542 G IGP G A + G G G G+ GL G G Sbjct: 1103 PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE 1162 Query: 543 GVGAGVPG-FG--AVPGALA-AAKAAKYGA----AVPGVLGGLGALGGVGIPGGVVGAGP 594 AG+PG FG PG + + K G PGV G +G G G PG GP Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGP 1222 Query: 595 AAAAAAAKAA 604 AA Sbjct: 1223 PGPPGHLTAA 1232 Score = 93.6 bits (231), Expect = 5e-19 Identities = 144/494 (29%), Positives = 176/494 (35%), Gaps = 44/494 (8%) Query: 204 PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV 263 PGG + G+ PG V G G P G P + + K G G Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAG--PPGSQGPRGERGPKGRPGPRGP 157 Query: 264 LPGVGGAGVPGVPGA-----IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 318 G GVPG PGA P G G+ P +A A K+ G+ GL+PG G Sbjct: 158 QGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSG-LGSQVGLMPGSVG 216 Query: 319 -FGP-GVVGVPG--AGVPGVGVPGAGIPVVPGAGIPGAAVP-GVVSPEAAAKAAAKAAKY 373 GP G G+ G G G PG G PG P G PE + + Sbjct: 217 PVGPRGPQGLQGQQGGAGPTGPPGE-------PGDPGPMGPIGSRGPEGPPGKPGEDGEP 269 Query: 374 G--ARPG-VGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV--GIS 428 G PG VG G P GA GFPG G+ G+ G G G+ G G G PG Sbjct: 270 GRNGNPGEVGFAGSP----GARGFPG-APGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAG 324 Query: 429 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 488 P A G+ PG G APG A G+ PG G+ + G P Sbjct: 325 PTGPMGAMGPLGPRGM-PGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP 383 Query: 489 GI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGA 546 G+ G G A + + +G+ G+PG G PG G PG + Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT---S 440 Query: 547 GVPGFGAVPGA-----LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAA 601 G PG PG+ + + PGV G G G G PG GP Sbjct: 441 GPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE 500 Query: 602 KAAAKAAQFGLVGAAG-LGGLGV-GGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLS 659 G VG G +G G G G PG GL G P A + G + G Sbjct: 501 GKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG-PKGAQGERGPVGSSGPKGSQGD 559 Query: 660 PIFPGGACLGKACG 673 P PG L A G Sbjct: 560 PGRPGEPGLPGARG 573 Score = 73.9 bits (180), Expect = 4e-13 Identities = 124/402 (30%), Positives = 139/402 (34%), Gaps = 64/402 (15%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPA----LGPGGKPLKPVPGGLAGA-------GLGA 67 P P GVPG G G PG +P +GP G P P G G GL Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRG 945 Query: 68 GLGAFPAVTFPG-ALVPGGVADAAAAYKAAKAG-------AGLGGVPGVGGLGVSAG--A 117 G+ V G A PGG D + + G AG G G+ G+ G Sbjct: 946 DPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERG 1005 Query: 118 VVPQPGAGVKPGKVPGVGLPGVY--PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 175 + PG PGKV G G PG V P VG PG P G PG GA Sbjct: 1006 MPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE-PG-PEGPAGNDGTPGRDGA 1063 Query: 176 FAGIPGVGPFGGPQPGVPLGYPIK--APKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGK 231 VG G P G P AP PG G P G+ P GP G G AGK Sbjct: 1064 ------VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGK 1117 Query: 232 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGT 290 G P GPQ + G G G G+ G+PG PG G G G Sbjct: 1118 RGLP-----GPQGPRGDKGDHGDRGDRGQKGHR---GFTGLQGLPGP-PGPNGEQGSAGI 1168 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350 P G P GP PGV G G P G PG P P G P Sbjct: 1169 PGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP-EGPPGEPGPPGP-PGPP 1226 Query: 351 G---AAVPGVVS----------PEAAAKAAAKAAKYGARPGV 379 G AA+ ++ PE AA K PGV Sbjct: 1227 GHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGV 1268 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 152 bits (383), Expect = 1e-36 Identities = 205/667 (30%), Positives = 239/667 (35%), Gaps = 89/667 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPALGPG-----GKPLKPVPGGLAGAGLGAGLGAFPAVTFPGA 80 P G PG P G PA PG G P KP G G G FP PG Sbjct: 116 PAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGT--PG- 172 Query: 81 LVPGGVADAAAAYKAAKAGAGLGGV---PGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLP 137 +PG +K + GL G+ PG G+ GA PG PG+ GLP Sbjct: 173 -LPG--------FKGIRGHNGLDGLKGQPGAPGVKGEPGA----PGENGTPGQTGARGLP 219 Query: 138 GV-----YPGGVLPGARFPGVG-VLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPG 191 G PG VG V P P G+ P PG G I VG G P Sbjct: 220 GERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPA 279 Query: 192 VPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAA 248 P G + P L G G P G L G G+ G AG G P G+ GP AA A Sbjct: 280 GPRG-EVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGA 338 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGV--PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKY 306 G AG G G PG P PG G G P A +A Sbjct: 339 TGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGP------ 392 Query: 307 GAAAGLVPGGPGF--GPGVVGVPGA-GVPGV-GVPG-------AGIPVVPG-AGIPGAAV 354 PG PG PG G+PGA G GV G PG AG+ G AG PG Sbjct: 393 -------PGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGE-- 443 Query: 355 PGVVSPEAAAKAAAKAAKYGARPGVGVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAG 409 PG++ P + G VG+ GI P GA G PG +G G G G Sbjct: 444 PGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPG-NIGFPGPKGPTG 502 Query: 410 VPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGV-----APGVGVAPG-VG 461 PG G G G+ G P+ A G+ G G PG PG G Sbjct: 503 DPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSG 562 Query: 462 VAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AG 520 A VG G+ G+ G GP G + AA + ++ G G Sbjct: 563 PAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKG 622 Query: 521 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 580 PG+ VG G +G+PG AG+PG K K + G +G G Sbjct: 623 EPGVVGAVGTAGPSGPSGLPGERGAAGIPG----------GKGEKGEPGLRGEIGNPGRD 672 Query: 581 GGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPA 640 G G PG V GPA A A A G G G G G +G G G G A Sbjct: 673 GARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG-ERGEVGPAGPNGFAGPAGA 731 Query: 641 AAAKAAK 647 A AK Sbjct: 732 AGQPGAK 738 Score = 151 bits (382), Expect = 2e-36 Identities = 214/666 (32%), Positives = 250/666 (37%), Gaps = 86/666 (12%) Query: 26 PGGVPGAIPGGV-PGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPG 84 P G+PG+ PG + P G P +G G +P P G AGA G FP P PG Sbjct: 449 PRGLPGS-PGNIGPAGKEGP-VGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTG-DPG 505 Query: 85 GVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGV 144 D K AGL G G G + GA P GV+ GK G PG Sbjct: 506 KNGD--------KGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQ-GPPGPPGFQG 556 Query: 145 LPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKL 203 LPG P P G KP G+ G F G+PG GP G P Sbjct: 557 LPG---------PSGPAGEVGKPGERGLHGEF-GLPGPAGPRGERGP------------- 593 Query: 204 PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV 263 PG G TG + GP G G G G P VG A + + GAAG+ Sbjct: 594 PGESGAAGPTGPIG-SRGPSGPPGPDGNKGEPGV--VGAVGTAGPSGPSGLPGERGAAGI 650 Query: 264 LPGVGGAGVPGVPGAI--PGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG 320 G G G PG+ G I PG G G G A A A + GAA P GP Sbjct: 651 PGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGS 710 Query: 321 PGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGA 375 PG G G P AG PGA G GA P GVV P AA A G Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP 770 Query: 376 RPGV----GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 431 PG G GG P G GFPG G G PG +G+ G G PG G G+ P Sbjct: 771 -PGPAGSRGDGGPP----GMTGFPG-AAGRTGPPGPSGISGPPGPPGPAGKEGLR-GPRG 823 Query: 432 QAAAAAKAAKYGLV--PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG------ 483 + + G V PG G G PG G+ APG+ PG Sbjct: 824 DQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERG 883 Query: 484 -VGVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 541 GVA +G PG + A A+ A + G+ G PG G PG G PG Sbjct: 884 LPGVAGAVGEPGPLGIAGPPGARGPPGAV--GSPGVN-GAPGEAGRDGNPG---NDGPPG 937 Query: 542 LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAA 601 G G PG + A A PG G +G G G G +GP A A Sbjct: 938 RDGQPGHKGERGYPGNIGPVGA----AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993 Query: 602 KAAAKAAQFGLVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLS 659 + G+ G G G G GL G+ G GL G+P A +G PG + Sbjct: 994 GPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLP----GIAGHHGDQGAPG-SVG 1048 Query: 660 PIFPGG 665 P P G Sbjct: 1049 PAGPRG 1054 Score = 148 bits (374), Expect = 1e-35 Identities = 210/663 (31%), Positives = 247/663 (37%), Gaps = 103/663 (15%) Query: 34 PGGVPG--GVFYPALGPGGKPLKPVPGGLAGA------GLGAGLGAFPAVTFPGALVPGG 85 P G PG G P GP G P P P GL G G G GLG P G + P G Sbjct: 46 PPGPPGRDGEDGPT-GPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM----GLMGPRG 100 Query: 86 VADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVL 145 AA A + G G PG G AGA P AG PGK G PG PG Sbjct: 101 PPGAAGA-PGPQGFQGPAGEPGEPGQTGPAGARGP---AG-PPGKAGEDGHPGK-PGR-- 152 Query: 146 PGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGG--PQPGVPLGYPIKA-PK 202 PG R GV+ P GA P PG+ G F GI G G QPG P +K P Sbjct: 153 PGER----GVVG--PQGARGFPGTPGLPG-FKGIRGHNGLDGLKGQPGAP---GVKGEPG 202 Query: 203 LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAG 262 PG G P TG G+ G G+ G P GP A + G G Sbjct: 203 APGENGTPGQTGAR-------GLPGERGRVGAP-----GPAGARGSDGSV------GPVG 244 Query: 263 VLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPG 322 +G AG PG PGA G I VG A A + G + P GP PG Sbjct: 245 PAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSG---PVGPPGNPG 301 Query: 323 VVGVPG----AGVPGVGVPGAGIPVVPG-AGIPG-------AAVPGVVSPEAAAKAAAKA 370 G+ G AG+PGV AG P +PG GIPG G+V A + ++ Sbjct: 302 ANGLTGAKGAAGLPGV----AGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGES 357 Query: 371 AKYGARPGVGVGGIPTYG-----VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 425 G G G P G G G G G PG+ G PG G+PG G GV Sbjct: 358 GNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG-SAGPPGPPGLRGSPGSRGLPGADGRAGV 416 Query: 426 GISPEAQAAA-----------AAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 474 P ++ A+ A + + GL+ G+ G G VGL PG+ Sbjct: 417 MGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGL-PGIDG 475 Query: 475 APG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 532 PG +G A G IG G K K A GA G G G PG Sbjct: 476 RPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPG 535 Query: 533 LGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA-------AVPGVLGGLGALGGVG 584 G G G PGF +PG A + K G +PG G G G G Sbjct: 536 PQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPG 595 Query: 585 IPGGVVGAGPAAAAAAAKAA---AKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 641 G GP + + + G+VGA G G G G+PG G GIP Sbjct: 596 ESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS-GPSGLPGERGAAGIPGGK 654 Query: 642 AAK 644 K Sbjct: 655 GEK 657 Score = 79.0 bits (193), Expect = 1e-14 Identities = 90/289 (31%), Positives = 106/289 (36%), Gaps = 26/289 (8%) Query: 400 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 459 G G G G PG G G G PG P AA+Y GVG+ PG G Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD-GKGVGLGPGPMGLMG 97 Query: 460 VGVAPGVGLAPGVGVAPGVGVAPG----VGVAPGIGPGGVAAAAKS---AAKVAAKAQLR 512 PG APG G PG G A GP G A K + Sbjct: 98 PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERG 157 Query: 513 AAAGLGA----GIPGLG--VGV----GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA-- 560 GA G PGL G+ G+ GL G PG+ G PG PG A Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217 Query: 561 --AKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 617 + + GA P G G G++G VG G + AGP A + G G AG Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAG 277 Query: 618 LGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 664 G G +G+PG+ G G P P A G A PG +P PG Sbjct: 278 PAG-PRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPG 325 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 150 bits (380), Expect = 3e-36 Identities = 208/676 (30%), Positives = 245/676 (36%), Gaps = 158/676 (23%) Query: 4 LTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGA 63 L P +LLLLL ++ P G GG G + P K ++P+ G G Sbjct: 2 LGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAG--YAPV-----KYIQPMQKGPVGP 54 Query: 64 GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPG 123 G G + + P L+P + K G G PG G PG Sbjct: 55 PFREGKGQYLEMPLP--LLPMDL----------KGEPGPPGKPGPRG----------PPG 92 Query: 124 AGVKPGKVPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 179 PGK PG+G PG++ P G PG G PG+P G P PG+ G GI Sbjct: 93 PPGFPGK-PGMGKPGLHGQPGPAGP-PGFSRMGKAGPPGLPGKVG-PPGQPGLRGE-PGI 148 Query: 180 PGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTG 237 G GP PG+P I P PG G+P GP G G G G P Sbjct: 149 RGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVP----------GPPGFQGEPGPQGEP-- 196 Query: 238 TGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 297 GP G G G LPG G G G PG PG+ G AG+G P Sbjct: 197 ---GPPGDRGLKGDN----GVGQPG-LPGAPGQG--GAPGP-PGLPGPAGLGKPGLDGLP 245 Query: 298 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGAGIPGAAVPG 356 A + G VPG G PG VG G GV GVGVPGA AG+PG P Sbjct: 246 GAPGDKGESGPPG--VPGPRG-EPGAVGPKGPPGVDGVGVPGA-------AGLPGPQGPS 295 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV 416 GA+ G G P +G G+ G+ G+PG G G GV Sbjct: 296 -----------------GAKGEPGTRGPPGL-IGPTGY-----GMPGLPGPKGDRGPAGV 332 Query: 417 PGV---GGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVG 473 PG+ G PG P Q G+G PG+ PG PG PG Sbjct: 333 PGLLGDRGEPGEDGEPGEQGPQ-----------GLGGPPGL---PGSAGLPGRRGPPGPK 378 Query: 474 VAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG 532 G G PGV G+ GP G+A G PG+ G+PG Sbjct: 379 GEAGPGGPPGVPGIRGDQGPSGLA-----------------------GKPGVPGERGLPG 415 Query: 533 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA 592 G PG G PGF PG PGV G LG G +G+PG Sbjct: 416 ---AHGPPGPTGPKGEPGFTGRPGG-------------PGVAGALGQKGDLGLPGQPGLR 459 Query: 593 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKY 648 GP+ A GL G G GL G G G PG G G PP Sbjct: 460 GPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTG-PPGVPGSPGIT 518 Query: 649 GVAARPGFGLSPIFPG 664 G PG P PG Sbjct: 519 GPPGPPGPPGPPGAPG 534 Score = 61.2 bits (147), Expect = 3e-09 Identities = 85/260 (32%), Positives = 104/260 (40%), Gaps = 38/260 (14%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPA----LGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 76 P GG PG +PG G+PG P GPGG P P G+ G +GL P V Sbjct: 353 PQGLGGPPG-LPGSAGLPGRRGPPGPKGEAGPGGPPGVP---GIRGDQGPSGLAGKPGVP 408 Query: 77 ----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV--KPGK 130 PGA P G K G G PG G+ AGA+ + G+ +PG Sbjct: 409 GERGLPGAHGPPGPT-------GPKGEPGFTGRPGGPGV---AGALGQKGDLGLPGQPGL 458 Query: 131 VPGVGLPGVY-PGGVLPGARFPGVGVLPGVPTGAGV-KPKAPGVGGAFA--GIPGVGPFG 186 G+PG+ P G + PG+ PG+P G + PG G G+PG Sbjct: 459 RGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGIT 518 Query: 187 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA-GKAGYPTGTGVGPQAA 245 GP PG P P PG G TG GGV GA GK G P G+G +A Sbjct: 519 GP-PGPP-----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQ-FGLGELSA 571 Query: 246 AAAAAKAAAKFGAGAAGVLP 265 A A A A +P Sbjct: 572 HATPAFTAVLTSPFPASGMP 591 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 149 bits (375), Expect = 1e-35 Identities = 165/503 (32%), Positives = 199/503 (39%), Gaps = 79/503 (15%) Query: 121 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 231 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 232 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 291 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 292 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 348 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 349 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 406 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 407 VAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 464 G PG+GG PG G+PG+ + P + G+V G PG PG+ P Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG-PPGPKGEPGLQGFP 437 Query: 465 GVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG----A 519 G G PG+ PG +G G GV + K + G Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497 Query: 520 GIPGLG---VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 576 GIPG+G +G PG+ G PGL G PG G PG A +G PG G Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKPGA 549 Query: 577 LGALGGVGIPGGVVGAGPAAAAA 599 LG G G+PG GP A Sbjct: 550 LGPQGQPGLPGPPGPPGPPGPPA 572 Score = 142 bits (358), Expect = 1e-33 Identities = 177/543 (32%), Positives = 215/543 (39%), Gaps = 96/543 (17%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLG 66 A P+ G + L S+ P G PG P G PG P G G KP P G G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG-K 159 Query: 67 AGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAG 125 G+ P PGA+ +PG + K G G+PG G PG Sbjct: 160 PGMPGMPGK--PGAMGMPGAKGEI-----GQKGEIGPMGIPGPQG----------PPG-- 200 Query: 126 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-G 183 P +PG+G PG G LPG P G G+P G++ G G PGV G Sbjct: 201 --PHGLPGIGKPG---GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255 Query: 184 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 243 P G P P+G P G G P TG P GP G GA G+ G P G P Sbjct: 256 PPGMHGPPGPVGLP--------GVGKPGVTG-FPGPQGPLGKPGAPGEPG-PQGPIGVPG 305 Query: 244 AAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 302 K G PG GG G G+PG +PG G+ G+G P Sbjct: 306 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPG-LPGPPGLPGIGKP--------GFP 356 Query: 303 AAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVV 358 K G VPG GP G +G PG G G PG G+P +PG G PGA G Sbjct: 357 GPKGDRGMGGVPGALGPRGEKGPIGAPGIG----GPPGEPGLPGIPGPMGPPGAI--GFP 410 Query: 359 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG-VG--- 414 P+ G + G+ G P G PGF +G G PG+ G+PG +G Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFP-------GKPGF-LGEVGPPGMRGLPGPIGPKG 462 Query: 415 -----GVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 469 GVPG+ GVPG+ + P+ + G PG+ PG+G G PG+ Sbjct: 463 EAGQKGVPGLPGVPGL-LGPKGEPGIPGDQGLQG-PPGI---PGIGGPSGPIGPPGI--- 514 Query: 470 PGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 529 PG PG+ PG PGIG GVA K A G PGL G Sbjct: 515 PGPKGEPGLPGPPGF---PGIGKPGVAGLHGPPGKPGALGP--------QGQPGLPGPPG 563 Query: 530 VPG 532 PG Sbjct: 564 PPG 566 Score = 133 bits (335), Expect = 5e-31 Identities = 173/485 (35%), Positives = 208/485 (42%), Gaps = 80/485 (16%) Query: 23 PSRPGGVPG-AIPG--GVPGGVFYPALG-PG--GKPLKPVPGGLAGAGLGAGL-GAFPAV 75 P P G+PG IPG G PG YP +G PG G P KP G+ GA G G + Sbjct: 131 PPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK----- 130 PG P G K G GL G PG G G PQ G K K Sbjct: 191 GIPGPQGPPGPHGLPGIGKPG--GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248 Query: 131 -VPGV-GLPGVY--PGGV-LPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGVG 183 PGV G PG++ PG V LPG PGV PG P G KP APG G G+PGV Sbjct: 249 GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ 307 Query: 184 PFGGPQPGVP-LGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV 240 GP PG+P +G P + +PG G P G+ LP GP G+ G GK G+P Sbjct: 308 ---GP-PGIPGIGKPGQ-DGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFP----- 356 Query: 241 GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGA-GVPGVPGAIPGIGGIAG-VGTPAAAAA 296 GP+ A G G + PG+GG G PG+PG IPG G G +G P Sbjct: 357 GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG-IPGPMGPPGAIGFPGPKGE 415 Query: 297 AAAAAKAAKYGAAA--GL--VPGGPGFGPGVVGVPGA-GVPG-VGVPG-AGIPVVPGAGI 349 G GL PG PGF G VG PG G+PG +G G AG VPG + Sbjct: 416 GGIVGPQGPPGPKGEPGLQGFPGKPGF-LGEVGPPGMRGLPGPIGPKGEAGQKGVPG--L 472 Query: 350 PGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAGGFPGFGVGVGGIPGVA 408 PG VPG++ P+ G PG+ G+GG P+ +G G PG G G+PG Sbjct: 473 PG--VPGLLGPKGEPGIPGDQGLQGP-PGIPGIGG-PSGPIGPPGIPG-PKGEPGLPGPP 527 Query: 409 GVPGVG-----------------------GVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 445 G PG+G G+PG G PG P +Y Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Query: 446 PGVGV 450 G+G+ Sbjct: 588 MGLGI 592 Score = 133 bits (334), Expect = 6e-31 Identities = 174/523 (33%), Positives = 202/523 (38%), Gaps = 100/523 (19%) Query: 142 GGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKA 200 G +P A G G P G P PG+ G GIPG+ GPQ GYP + Sbjct: 108 GKEIPLASLRGEQGPRGEPGPRG-PPGPPGLPGH--GIPGIKGKPGPQ-----GYPGVGK 159 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGA 260 P +PG G P G +P G G G G G P GPQ G Sbjct: 160 PGMPGMPGKPGAMG-MPGAKGEIGQKGEIGPMGIP-----GPQ-------------GPPG 200 Query: 261 AGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF 319 LPG+G G PG+PG PG G G G P A V G PG Sbjct: 201 PHGLPGIGKPGGPGLPGQ-PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGM 259 Query: 320 G--PGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 376 PG VG+PG G PGV G PG P+ G PGA PG P+ G Sbjct: 260 HGPPGPVGLPGVGKPGVTGFPGPQGPL----GKPGA--PGEPGPQGPIGVPGVQGPPGI- 312 Query: 377 PGVGV---GGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVG--GVPGVGGVPGVGISP 429 PG+G GIP G GFPG G+ G+PG G+PG+G G PG G G+G P Sbjct: 313 PGIGKPGQDGIP----GQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP 368 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 A K +G APG+G PG PG+ PG PG PG G Sbjct: 369 GALGPRGEKGP-------IG-APGIGGPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGG 417 Query: 490 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA 546 I GP G + GL G PG VG PG+ G+PG +G Sbjct: 418 IVGPQGPPGP-------------KGEPGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGP 460 Query: 547 -------GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 599 GVPG VPG L PG+ G G G GIPG +GP Sbjct: 461 KGEAGQKGVPGLPGVPGLLGPK-------GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513 Query: 600 AAKAAAKAAQFGLVGAAGLGGLGVGGL----GVPGVGGLGGIP 638 + G G G+G GV GL G PG G G P Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQP 556 Score = 124 bits (310), Expect = 4e-28 Identities = 163/540 (30%), Positives = 198/540 (36%), Gaps = 109/540 (20%) Query: 164 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 217 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 218 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 277 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 278 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 333 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 334 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 389 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 390 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 449 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 450 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 509 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 510 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 568 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 569 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 609 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 610 FGLVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G VG G+ GL G G GV GL G+P K + G+ G P PG Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPK-GEPGIPGDQGLQGPPGIPG 501 Score = 103 bits (258), Expect = 4e-22 Identities = 130/397 (32%), Positives = 154/397 (38%), Gaps = 69/397 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPA----LGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFP 78 P P G+PG G PG +P LG G P +P P G G G P + P Sbjct: 262 PPGPVGLPGV---GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP 318 Query: 79 GAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLP 137 G +PG + K GL G+PG GL P P G VPG P Sbjct: 319 GQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGP 373 Query: 138 GVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-------VGPFGGPQP 190 G + GA PG+G PG P G+ P G GA G PG VGP G P P Sbjct: 374 RGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKGEGGIVGPQGPPGP 427 Query: 191 -GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAA 246 G P G+P K P G G P G LP GP G AG G G P G+ GP+ Sbjct: 428 KGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485 Query: 247 AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAA 301 + G G+ G G PG+PG +PG G G+G P A Sbjct: 486 GIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545 Query: 302 KAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP---GAGIP--GAAV 354 K PG GP PG+ G PG PG P A +P P G +P G + Sbjct: 546 K-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Query: 355 PGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 391 GV P A YGA+ G G P Y + A Sbjct: 593 DGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 149 bits (375), Expect = 1e-35 Identities = 165/503 (32%), Positives = 199/503 (39%), Gaps = 79/503 (15%) Query: 121 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 231 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 232 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 291 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 292 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 348 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 349 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 406 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 407 VAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 464 G PG+GG PG G+PG+ + P + G+V G PG PG+ P Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG-PPGPKGEPGLQGFP 437 Query: 465 GVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG----A 519 G G PG+ PG +G G GV + K + G Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497 Query: 520 GIPGLG---VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 576 GIPG+G +G PG+ G PGL G PG G PG A +G PG G Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKPGA 549 Query: 577 LGALGGVGIPGGVVGAGPAAAAA 599 LG G G+PG GP A Sbjct: 550 LGPQGQPGLPGPPGPPGPPGPPA 572 Score = 142 bits (358), Expect = 1e-33 Identities = 177/543 (32%), Positives = 215/543 (39%), Gaps = 96/543 (17%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLG 66 A P+ G + L S+ P G PG P G PG P G G KP P G G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG-K 159 Query: 67 AGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAG 125 G+ P PGA+ +PG + K G G+PG G PG Sbjct: 160 PGMPGMPGK--PGAMGMPGAKGEI-----GQKGEIGPMGIPGPQG----------PPG-- 200 Query: 126 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-G 183 P +PG+G PG G LPG P G G+P G++ G G PGV G Sbjct: 201 --PHGLPGIGKPG---GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG 255 Query: 184 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 243 P G P P+G P G G P TG P GP G GA G+ G P G P Sbjct: 256 PPGMHGPPGPVGLP--------GVGKPGVTG-FPGPQGPLGKPGAPGEPG-PQGPIGVPG 305 Query: 244 AAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 302 K G PG GG G G+PG +PG G+ G+G P Sbjct: 306 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPG-LPGPPGLPGIGKP--------GFP 356 Query: 303 AAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVV 358 K G VPG GP G +G PG G G PG G+P +PG G PGA G Sbjct: 357 GPKGDRGMGGVPGALGPRGEKGPIGAPGIG----GPPGEPGLPGIPGPMGPPGAI--GFP 410 Query: 359 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG-VG--- 414 P+ G + G+ G P G PGF +G G PG+ G+PG +G Sbjct: 411 GPKGEGGIVGPQGPPGPKGEPGLQGFP-------GKPGF-LGEVGPPGMRGLPGPIGPKG 462 Query: 415 -----GVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 469 GVPG+ GVPG+ + P+ + G PG+ PG+G G PG+ Sbjct: 463 EAGQKGVPGLPGVPGL-LGPKGEPGIPGDQGLQG-PPGI---PGIGGPSGPIGPPGI--- 514 Query: 470 PGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 529 PG PG+ PG PGIG GVA K A G PGL G Sbjct: 515 PGPKGEPGLPGPPGF---PGIGKPGVAGLHGPPGKPGALGP--------QGQPGLPGPPG 563 Query: 530 VPG 532 PG Sbjct: 564 PPG 566 Score = 133 bits (335), Expect = 5e-31 Identities = 173/485 (35%), Positives = 208/485 (42%), Gaps = 80/485 (16%) Query: 23 PSRPGGVPG-AIPG--GVPGGVFYPALG-PG--GKPLKPVPGGLAGAGLGAGL-GAFPAV 75 P P G+PG IPG G PG YP +G PG G P KP G+ GA G G + Sbjct: 131 PPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPM 190 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK----- 130 PG P G K G GL G PG G G PQ G K K Sbjct: 191 GIPGPQGPPGPHGLPGIGKPG--GPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMP 248 Query: 131 -VPGV-GLPGVY--PGGV-LPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGVG 183 PGV G PG++ PG V LPG PGV PG P G KP APG G G+PGV Sbjct: 249 GAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ 307 Query: 184 PFGGPQPGVP-LGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV 240 GP PG+P +G P + +PG G P G+ LP GP G+ G GK G+P Sbjct: 308 ---GP-PGIPGIGKPGQ-DGIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFP----- 356 Query: 241 GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGA-GVPGVPGAIPGIGGIAG-VGTPAAAAA 296 GP+ A G G + PG+GG G PG+PG IPG G G +G P Sbjct: 357 GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG-IPGPMGPPGAIGFPGPKGE 415 Query: 297 AAAAAKAAKYGAAA--GL--VPGGPGFGPGVVGVPGA-GVPG-VGVPG-AGIPVVPGAGI 349 G GL PG PGF G VG PG G+PG +G G AG VPG + Sbjct: 416 GGIVGPQGPPGPKGEPGLQGFPGKPGF-LGEVGPPGMRGLPGPIGPKGEAGQKGVPG--L 472 Query: 350 PGAAVPGVVSPEAAAKAAAKAAKYGARPGV-GVGGIPTYGVGAGGFPGFGVGVGGIPGVA 408 PG VPG++ P+ G PG+ G+GG P+ +G G PG G G+PG Sbjct: 473 PG--VPGLLGPKGEPGIPGDQGLQGP-PGIPGIGG-PSGPIGPPGIPG-PKGEPGLPGPP 527 Query: 409 GVPGVG-----------------------GVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 445 G PG+G G+PG G PG P +Y Sbjct: 528 GFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Query: 446 PGVGV 450 G+G+ Sbjct: 588 MGLGI 592 Score = 133 bits (334), Expect = 6e-31 Identities = 174/523 (33%), Positives = 202/523 (38%), Gaps = 100/523 (19%) Query: 142 GGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKA 200 G +P A G G P G P PG+ G GIPG+ GPQ GYP + Sbjct: 108 GKEIPLASLRGEQGPRGEPGPRG-PPGPPGLPGH--GIPGIKGKPGPQ-----GYPGVGK 159 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGA 260 P +PG G P G +P G G G G G P GPQ G Sbjct: 160 PGMPGMPGKPGAMG-MPGAKGEIGQKGEIGPMGIP-----GPQ-------------GPPG 200 Query: 261 AGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGF 319 LPG+G G PG+PG PG G G G P A V G PG Sbjct: 201 PHGLPGIGKPGGPGLPGQ-PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGM 259 Query: 320 G--PGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 376 PG VG+PG G PGV G PG P+ G PGA PG P+ G Sbjct: 260 HGPPGPVGLPGVGKPGVTGFPGPQGPL----GKPGA--PGEPGPQGPIGVPGVQGPPGI- 312 Query: 377 PGVGV---GGIPTYGVGAGGFPGFG--VGVGGIPGVAGVPGVG--GVPGVGGVPGVGISP 429 PG+G GIP G GFPG G+ G+PG G+PG+G G PG G G+G P Sbjct: 313 PGIGKPGQDGIP----GQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVP 368 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 A K +G APG+G PG PG+ PG PG PG G Sbjct: 369 GALGPRGEKGP-------IG-APGIGGPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGG 417 Query: 490 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA 546 I GP G + GL G PG VG PG+ G+PG +G Sbjct: 418 IVGPQGPPGP-------------KGEPGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGP 460 Query: 547 -------GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 599 GVPG VPG L PG+ G G G GIPG +GP Sbjct: 461 KGEAGQKGVPGLPGVPGLLGPK-------GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513 Query: 600 AAKAAAKAAQFGLVGAAGLGGLGVGGL----GVPGVGGLGGIP 638 + G G G+G GV GL G PG G G P Sbjct: 514 IPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQP 556 Score = 124 bits (310), Expect = 4e-28 Identities = 163/540 (30%), Positives = 198/540 (36%), Gaps = 109/540 (20%) Query: 164 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 217 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 218 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 277 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 278 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 333 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 334 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 389 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 390 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 449 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 450 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 509 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 510 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 568 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 569 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 609 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 610 FGLVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G VG G+ GL G G GV GL G+P K + G+ G P PG Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPK-GEPGIPGDQGLQGPPGIPG 501 Score = 103 bits (258), Expect = 4e-22 Identities = 130/397 (32%), Positives = 154/397 (38%), Gaps = 69/397 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPA----LGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFP 78 P P G+PG G PG +P LG G P +P P G G G P + P Sbjct: 262 PPGPVGLPGV---GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP 318 Query: 79 GAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLP 137 G +PG + K GL G+PG GL P P G VPG P Sbjct: 319 GQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGP 373 Query: 138 GVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-------VGPFGGPQP 190 G + GA PG+G PG P G+ P G GA G PG VGP G P P Sbjct: 374 RGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKGEGGIVGPQGPPGP 427 Query: 191 -GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAA 246 G P G+P K P G G P G LP GP G AG G G P G+ GP+ Sbjct: 428 KGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485 Query: 247 AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAA 301 + G G+ G G PG+PG +PG G G+G P A Sbjct: 486 GIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545 Query: 302 KAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP---GAGIP--GAAV 354 K PG GP PG+ G PG PG P A +P P G +P G + Sbjct: 546 K-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Query: 355 PGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 391 GV P A YGA+ G G P Y + A Sbjct: 593 DGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 147 bits (372), Expect = 2e-35 Identities = 203/693 (29%), Positives = 258/693 (37%), Gaps = 91/693 (13%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGA-GLGAGLGAFPAVTFPG 79 P PG G PG P G+PG GP G P GL G GL G PG Sbjct: 604 PGLPGEKGHPG--PPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPG 661 Query: 80 ALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV 139 + P G + K GL G PG G S G +PG+ PG V LPG Sbjct: 662 SYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKG----EPGS---PGLVHLPELPG- 712 Query: 140 YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIK 199 PG R G LPG P G K PG+ G+ G+PG G G G Sbjct: 713 -----FPGPR--GEKGLPGFP-GLPGKDGLPGMIGS-PGLPGSKGATGDIFGAENG---- 759 Query: 200 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 258 PG GL TG + G G+ G G G P G G + + + Sbjct: 760 ---APGEQGLQGLTGHKGF-LGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTP 815 Query: 259 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGP 317 G++G G +G+PG PG PGI G G GT + K G +PG P Sbjct: 816 GSSGPYGIKGKSGLPGAPG-FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKG--LPGNP 872 Query: 318 GF--------GPGVVGVPGAGVPG--------VGVPGA-GIPVVPGA-GIPGAAVPGVVS 359 G PGV G+P P VG PG G+P +PG G+ G +PG Sbjct: 873 GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKG--IPGSTG 930 Query: 360 PEAAAKAAAKAAKYGARPGVGVGGIPTY-----------------GVGAGGFPGFGVGVG 402 + A + G R G GIP+ G+ GFPG Sbjct: 931 KMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG----PR 986 Query: 403 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 462 G G AG PG G+PG G+PG+ + GL PG+ + G+ PG+ Sbjct: 987 GDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITGFPGM-- 1043 Query: 463 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GI 521 PG + G+ +PG+ PG PG+ G + + K Q + G G Sbjct: 1044 -PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1098 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 581 GL +G PG G G+ G+PG PG A + G +PG G GA+G Sbjct: 1099 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSGHQGAIG 1154 Query: 582 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGLGGIPPA 640 +G PG + G G G G GV G G+PG G G P Sbjct: 1155 PLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI 1214 Query: 641 AAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 673 K G+ + G P G A L A G Sbjct: 1215 GIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPG 1247 Score = 139 bits (351), Expect = 7e-33 Identities = 201/694 (28%), Positives = 266/694 (38%), Gaps = 114/694 (16%) Query: 28 GVPGAIPGGVPG--GVFYPALGPGGKPLKPVPG-----GLAGAGLGAGL-GAFPAVTFPG 79 G+PG P G G GV P G K PG G+ G GL G + G Sbjct: 297 GLPG--PRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDG 354 Query: 80 ALVPGGVADAAAAYKAAKAG-------AGLGGVPGVGGLGVSAGAVVPQPGAGVK----- 127 A++ G D G G GVPG+ L GA+ PQ G+K Sbjct: 355 AVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGN 414 Query: 128 PGK-------VPGV-GLPGVY--PGGVLPG----------ARFPGVGVLPGVPTGAGVK- 166 PG+ +PG GLPG PG P + FPG+ G G+K Sbjct: 415 PGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKG 474 Query: 167 -PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK-----LPYGY 220 G G+P GP G P P P G I P L G G + G P Sbjct: 475 IKGDSGFCACDGGVPNTGPPGEPGPPGPWGL-IGLPGLKGARGDRGSGGAQGPAGAPGLV 533 Query: 221 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 280 GP G +G GK G P + + Q + ++ G GV+ G GVPG+PG +P Sbjct: 534 GPLGPSGPKGKKGEPILSTI--QGMPGDRGDSGSQ---GFRGVIGEPGKDGVPGLPG-LP 587 Query: 281 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG----PGVVGVPGA----GVP 332 G+ G G G P + G PG PG G PG G+PG G+P Sbjct: 588 GLPGDGGQGFPGEKGLPGLPGEKGHPGP-----PGLPGNGLPGLPGPRGLPGDKGKDGLP 642 Query: 333 GV-GVPGA-GIP---VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGG 383 G G+PG+ GI ++PG+ G PG PG P+ + + G+ G G Sbjct: 643 GQQGLPGSKGITLPCIIPGSYGPSGFPGT--PGFPGPKGSRGLPGTPGQPGSSGSKGEPG 700 Query: 384 IP--TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 441 P + GFPG G G+PG G+PG G+PG+ G PG+ P ++ A Sbjct: 701 SPGLVHLPELPGFPG-PRGEKGLPGFPGLPGKDGLPGMIGSPGL---PGSKGATGDIFGA 756 Query: 442 YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 501 PG G+ G G+ GV PG+ G +PG PG V Sbjct: 757 ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGT-PGQVGQPGTP 815 Query: 502 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA 561 + + ++ G PG+ G G G PG V G+PG +PG Sbjct: 816 GSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN---- 871 Query: 562 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 621 PG++G G+ G G+ G +GP + G VG G+ GL Sbjct: 872 ---------PGLVGLKGSPGSPGVAGLPALSGP---------KGEKGSVGFVGFPGIPGL 913 Query: 622 GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 655 G+PG GL GI P + K G A PG Sbjct: 914 P----GIPGTRGLKGI-PGSTGKMGPSGRAGTPG 942 Score = 132 bits (332), Expect = 1e-30 Identities = 209/738 (28%), Positives = 269/738 (36%), Gaps = 140/738 (18%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL 60 + GL +PG +L P G PG PG V P G P P G+ Sbjct: 781 LPGLKGVHGKPG-------LLGPKGERGSPGT-----PGQVGQP-----GTPGSSGPYGI 823 Query: 61 AGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGVSAGA 117 G G FP ++ PG G + K GL G PG+ GL S G+ Sbjct: 824 KGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGS 883 Query: 118 --VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 175 V P G+ VG G FPG+ LPG+P G+K PG G Sbjct: 884 PGVAGLPALSGPKGEKGSVGFVG-----------FPGIPGLPGIPGTRGLKG-IPGSTGK 931 Query: 176 F-----AGIPGV-------GPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGP 222 AG PG GP G P P P+ +K K G G + G P G Sbjct: 932 MGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK--GSQGSAGSNG-FPGPRGD 988 Query: 223 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPG 281 G AG G G P G+ P + K G G LPG+ G +G+ G PG +PG Sbjct: 989 KGEAGRPGPPGLPGAPGL-PGIIKGVSGKPGPPGFMGIRG-LPGLKGSSGITGFPG-MPG 1045 Query: 282 IGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV--------PGGPGFGP--------GVV 324 G G+ G+P A+ G + PG GF G + Sbjct: 1046 ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNI 1105 Query: 325 GVPG-------AGVPG-VGVPGA-GIPVVPGA----GIPGAA----------VPGVVSPE 361 G PG GV G VG+PGA G P V G G+PG++ PG++ P+ Sbjct: 1106 GFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPK 1165 Query: 362 AAAKAAAKAAKYG--------ARPGVGVGGIPTYG-----VGAGGFPGFGVGVGGIPGV- 407 G PG + G+P G G+PG G+G G PG+ Sbjct: 1166 GFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLR 1225 Query: 408 -----AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 462 G PG+ G G+ G PG+ + P A + GL G PG PG Sbjct: 1226 GQKGDRGFPGLQGPAGLPGAPGISL-PSLIAGQPGDPGRPGL-DGERGRPGPAGPPG--- 1280 Query: 463 APGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 521 PG G PG PG+ G G G+ + ++ K +R G G Sbjct: 1281 PPGPSSNQGDTGDPGF---PGIPGPKGPKGDQGIPGFSGLPGELGLKG-MRGEPGF-MGT 1335 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 581 PG VG PG G PG+ AG G + G A+ PG LG G G Sbjct: 1336 PG---KVGPPG---DPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1389 Query: 582 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIP- 638 G+ G GP + G+ G G GL G LG PG+ GL G P Sbjct: 1390 IPGLTGDPGAQGPVGLQGSKGLP------GIPGKDGPSGLPGPPGALGDPGLPGLQGPPG 1443 Query: 639 -PAAAAKAAKYGVAARPG 655 A + +G+ PG Sbjct: 1444 FEGAPGQQGPFGMPGMPG 1461 Score = 130 bits (328), Expect = 3e-30 Identities = 207/697 (29%), Positives = 254/697 (36%), Gaps = 93/697 (13%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFP 78 I P G PGA+ P G PG GP G P P G G G G V P Sbjct: 182 ITGPQGAPGFPGAVGPAGPPG-----LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLP 236 Query: 79 GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAGAVVPQPGAGVKPGKVPGVGLP 137 G P K G G PG G G+S P G + G+ G+P Sbjct: 237 GPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIP 296 Query: 138 GVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKA--PGVGGAFAGIPGV-GPFGGPQPGVP 193 G LPG R P G + G P G K PG+ G F GI G G G P P V Sbjct: 297 G------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG-FQGIEGQKGDIGLPGPDVF 349 Query: 194 L---GYPIKA-PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV----GPQAA 245 + G I P PG GLP G G G+ G +G G P +GV GPQ Sbjct: 350 IDIDGAVISGNPGDPGVPGLPGLKGD----EGIQGLRGPSGVPGLPALSGVPGALGPQGF 405 Query: 246 AAAAAKAA--AKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 302 + GAAG LPG G G PG PG + + + Sbjct: 406 PGLKGDQGNPGRTTIGAAG-LPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQ 464 Query: 303 AAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA----GIPVVPGA-------GIP 350 K + G GF GVP G PG G PG G+P + GA G Sbjct: 465 GPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQ 524 Query: 351 G-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAG 409 G A PG+V P + K + G+ G G G GF GV G PG G Sbjct: 525 GPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPG----DRGDSGSQGFR-GVIGEPGKDG 579 Query: 410 VPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA--PGVGVAPGVG 467 VPG+ G+PG+ G G G E + PG+ PG G+ PG PG Sbjct: 580 VPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGL---PGNGLPGLPGPRGLPGDK 636 Query: 468 LAPGVGVAPGVGVAPGVG---VAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG 523 G+ G+ + G+ + PG GP G + R G G PG Sbjct: 637 GKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS----RGLPGT-PGQPG 691 Query: 524 LGVGVGVPG------LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 577 G PG L G PG G+PGF +PG +PG++G Sbjct: 692 SSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK----------DGLPGMIGSP 741 Query: 578 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGG----LGVPGVG 632 G G G G + GA A + G +G +GL GL GV G LG G Sbjct: 742 GLPGSKGATGDIFGAENGAPGEQGLQGLTGHK-GFLGDSGLPGLKGVHGKPGLLGPKGER 800 Query: 633 GLGGIP-----PAAAAKAAKYGVAARPGFGLSPIFPG 664 G G P P + YG+ + G +P FPG Sbjct: 801 GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 837 Score = 123 bits (309), Expect = 5e-28 Identities = 203/715 (28%), Positives = 257/715 (35%), Gaps = 138/715 (19%) Query: 43 YPALGPGGKPLKPV----PGGLAGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAK 97 +P G G+P P+ P G G GL FPG L P G K K Sbjct: 43 FPEKGARGRP-GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGP-------KGDK 94 Query: 98 AGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGV 155 G+ G G+ G+ G P+ PG G VG PG P G +PG+ Sbjct: 95 GPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLG 146 Query: 156 LPGVPTGAGVKPKAPGVGGAF------AGIPGVGPFGGPQ--PGVPLGY-PIKAPKLPGG 206 PG+P G K G+F G+PG+ GPQ PG P P P L G Sbjct: 147 PPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGP 206 Query: 207 YGLP---YTTGKLPYGY----GPGGVAGAAGKAGYPTGTG----VG-PQAAAAAAAKAAA 254 G P G + G+ G G G G AG P TG +G P+ + + Sbjct: 207 PGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGP 266 Query: 255 KFGAGAAGV--LPGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAA 309 K G +G PG+G G G G IPG+ G G +G+ K G Sbjct: 267 KGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG-- 324 Query: 310 AGLVPGGPGFGPGVVGVPG-AGVPG----VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAA 363 PG GF G+ G G G+PG + + GA I PG G+PG +PG+ E Sbjct: 325 ---FPGLNGF-QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG--LPGLKGDEGI 378 Query: 364 AKAAAKAAKYGARPGVGVGGIPTY-----GVGAGGFPGF----------GVGVGGIPGVA 408 G R GV G+P +G GFPG +G G+PG Sbjct: 379 ---------QGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRD 429 Query: 409 GVPGVGGVPG--------------VGGVPGVGISPEAQAAAAAKAAK--------YGLVP 446 G+PG G PG G PG+ + K K G VP Sbjct: 430 GLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVP 489 Query: 447 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGP-GGVAAAAKSAAK 504 G PG PG G+ G G G A G APG +GP G K Sbjct: 490 NTG-PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEP 548 Query: 505 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 564 + + Q G+PG G G G PG G+PG +PG Sbjct: 549 ILSTIQ---------GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPG 599 Query: 565 KYGAAVPGVLGGLGALGGVGIPG-GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL---- 618 + G +PG+ G G G G+PG G+ G GP Q GL G+ G+ Sbjct: 600 EKG--LPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPC 657 Query: 619 ---GGLGVGGL----GVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 664 G G G G PG G G+P P + G PG P PG Sbjct: 658 IIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPG 712 Score = 92.8 bits (229), Expect = 9e-19 Identities = 155/530 (29%), Positives = 195/530 (36%), Gaps = 89/530 (16%) Query: 183 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 236 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 53 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 110 Query: 237 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 292 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 111 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 161 Query: 293 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 349 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 162 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 206 Query: 350 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 407 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 207 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 263 Query: 408 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 467 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 264 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 317 Query: 468 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 318 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 373 Query: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 374 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 431 Query: 586 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL---------------- 626 PG GP + + K + F GL G G G LG+ G+ Sbjct: 432 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 491 Query: 627 ------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFGLSPIFPGG 665 G PG GL G+P A+ + G A PG + P+ P G Sbjct: 492 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 540 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 147 bits (372), Expect = 2e-35 Identities = 203/693 (29%), Positives = 258/693 (37%), Gaps = 91/693 (13%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGA-GLGAGLGAFPAVTFPG 79 P PG G PG P G+PG GP G P GL G GL G PG Sbjct: 603 PGLPGEKGHPG--PPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPG 660 Query: 80 ALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV 139 + P G + K GL G PG G S G +PG+ PG V LPG Sbjct: 661 SYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKG----EPGS---PGLVHLPELPG- 711 Query: 140 YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIK 199 PG R G LPG P G K PG+ G+ G+PG G G G Sbjct: 712 -----FPGPR--GEKGLPGFP-GLPGKDGLPGMIGS-PGLPGSKGATGDIFGAENG---- 758 Query: 200 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 258 PG GL TG + G G+ G G G P G G + + + Sbjct: 759 ---APGEQGLQGLTGHKGF-LGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTP 814 Query: 259 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGP 317 G++G G +G+PG PG PGI G G GT + K G +PG P Sbjct: 815 GSSGPYGIKGKSGLPGAPG-FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKG--LPGNP 871 Query: 318 GF--------GPGVVGVPGAGVPG--------VGVPGA-GIPVVPGA-GIPGAAVPGVVS 359 G PGV G+P P VG PG G+P +PG G+ G +PG Sbjct: 872 GLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKG--IPGSTG 929 Query: 360 PEAAAKAAAKAAKYGARPGVGVGGIPTY-----------------GVGAGGFPGFGVGVG 402 + A + G R G GIP+ G+ GFPG Sbjct: 930 KMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG----PR 985 Query: 403 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 462 G G AG PG G+PG G+PG+ + GL PG+ + G+ PG+ Sbjct: 986 GDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITGFPGM-- 1042 Query: 463 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GI 521 PG + G+ +PG+ PG PG+ G + + K Q + G G Sbjct: 1043 -PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGFKGTKGR 1097 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 581 GL +G PG G G+ G+PG PG A + G +PG G GA+G Sbjct: 1098 DGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSGHQGAIG 1153 Query: 582 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGLGGIPPA 640 +G PG + G G G G GV G G+PG G G P Sbjct: 1154 PLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGI 1213 Query: 641 AAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 673 K G+ + G P G A L A G Sbjct: 1214 GIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPG 1246 Score = 139 bits (351), Expect = 7e-33 Identities = 201/694 (28%), Positives = 266/694 (38%), Gaps = 114/694 (16%) Query: 28 GVPGAIPGGVPG--GVFYPALGPGGKPLKPVPG-----GLAGAGLGAGL-GAFPAVTFPG 79 G+PG P G G GV P G K PG G+ G GL G + G Sbjct: 296 GLPG--PRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDG 353 Query: 80 ALVPGGVADAAAAYKAAKAG-------AGLGGVPGVGGLGVSAGAVVPQPGAGVK----- 127 A++ G D G G GVPG+ L GA+ PQ G+K Sbjct: 354 AVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGN 413 Query: 128 PGK-------VPGV-GLPGVY--PGGVLPG----------ARFPGVGVLPGVPTGAGVK- 166 PG+ +PG GLPG PG P + FPG+ G G+K Sbjct: 414 PGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKG 473 Query: 167 -PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK-----LPYGY 220 G G+P GP G P P P G I P L G G + G P Sbjct: 474 IKGDSGFCACDGGVPNTGPPGEPGPPGPWGL-IGLPGLKGARGDRGSGGAQGPAGAPGLV 532 Query: 221 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 280 GP G +G GK G P + + Q + ++ G GV+ G GVPG+PG +P Sbjct: 533 GPLGPSGPKGKKGEPILSTI--QGMPGDRGDSGSQ---GFRGVIGEPGKDGVPGLPG-LP 586 Query: 281 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG----PGVVGVPGA----GVP 332 G+ G G G P + G PG PG G PG G+PG G+P Sbjct: 587 GLPGDGGQGFPGEKGLPGLPGEKGHPGP-----PGLPGNGLPGLPGPRGLPGDKGKDGLP 641 Query: 333 GV-GVPGA-GIP---VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGG 383 G G+PG+ GI ++PG+ G PG PG P+ + + G+ G G Sbjct: 642 GQQGLPGSKGITLPCIIPGSYGPSGFPGT--PGFPGPKGSRGLPGTPGQPGSSGSKGEPG 699 Query: 384 IP--TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK 441 P + GFPG G G+PG G+PG G+PG+ G PG+ P ++ A Sbjct: 700 SPGLVHLPELPGFPG-PRGEKGLPGFPGLPGKDGLPGMIGSPGL---PGSKGATGDIFGA 755 Query: 442 YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 501 PG G+ G G+ GV PG+ G +PG PG V Sbjct: 756 ENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGT-PGQVGQPGTP 814 Query: 502 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA 561 + + ++ G PG+ G G G PG V G+PG +PG Sbjct: 815 GSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN---- 870 Query: 562 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 621 PG++G G+ G G+ G +GP + G VG G+ GL Sbjct: 871 ---------PGLVGLKGSPGSPGVAGLPALSGP---------KGEKGSVGFVGFPGIPGL 912 Query: 622 GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 655 G+PG GL GI P + K G A PG Sbjct: 913 P----GIPGTRGLKGI-PGSTGKMGPSGRAGTPG 941 Score = 132 bits (332), Expect = 1e-30 Identities = 209/738 (28%), Positives = 269/738 (36%), Gaps = 140/738 (18%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGL 60 + GL +PG +L P G PG PG V P G P P G+ Sbjct: 780 LPGLKGVHGKPG-------LLGPKGERGSPGT-----PGQVGQP-----GTPGSSGPYGI 822 Query: 61 AGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGVSAGA 117 G G FP ++ PG G + K GL G PG+ GL S G+ Sbjct: 823 KGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGS 882 Query: 118 --VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 175 V P G+ VG G FPG+ LPG+P G+K PG G Sbjct: 883 PGVAGLPALSGPKGEKGSVGFVG-----------FPGIPGLPGIPGTRGLKG-IPGSTGK 930 Query: 176 F-----AGIPGV-------GPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGP 222 AG PG GP G P P P+ +K K G G + G P G Sbjct: 931 MGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK--GSQGSAGSNG-FPGPRGD 987 Query: 223 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPG 281 G AG G G P G+ P + K G G LPG+ G +G+ G PG +PG Sbjct: 988 KGEAGRPGPPGLPGAPGL-PGIIKGVSGKPGPPGFMGIRG-LPGLKGSSGITGFPG-MPG 1044 Query: 282 IGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV--------PGGPGFGP--------GVV 324 G G+ G+P A+ G + PG GF G + Sbjct: 1045 ESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNI 1104 Query: 325 GVPG-------AGVPG-VGVPGA-GIPVVPGA----GIPGAA----------VPGVVSPE 361 G PG GV G VG+PGA G P V G G+PG++ PG++ P+ Sbjct: 1105 GFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPK 1164 Query: 362 AAAKAAAKAAKYG--------ARPGVGVGGIPTYG-----VGAGGFPGFGVGVGGIPGV- 407 G PG + G+P G G+PG G+G G PG+ Sbjct: 1165 GFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLR 1224 Query: 408 -----AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 462 G PG+ G G+ G PG+ + P A + GL G PG PG Sbjct: 1225 GQKGDRGFPGLQGPAGLPGAPGISL-PSLIAGQPGDPGRPGL-DGERGRPGPAGPPG--- 1279 Query: 463 APGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 521 PG G PG PG+ G G G+ + ++ K +R G G Sbjct: 1280 PPGPSSNQGDTGDPGF---PGIPGPKGPKGDQGIPGFSGLPGELGLKG-MRGEPGF-MGT 1334 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 581 PG VG PG G PG+ AG G + G A+ PG LG G G Sbjct: 1335 PG---KVGPPG---DPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDG 1388 Query: 582 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIP- 638 G+ G GP + G+ G G GL G LG PG+ GL G P Sbjct: 1389 IPGLTGDPGAQGPVGLQGSKGLP------GIPGKDGPSGLPGPPGALGDPGLPGLQGPPG 1442 Query: 639 -PAAAAKAAKYGVAARPG 655 A + +G+ PG Sbjct: 1443 FEGAPGQQGPFGMPGMPG 1460 Score = 130 bits (328), Expect = 3e-30 Identities = 207/697 (29%), Positives = 254/697 (36%), Gaps = 93/697 (13%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFP 78 I P G PGA+ P G PG GP G P P G G G G V P Sbjct: 181 ITGPQGAPGFPGAVGPAGPPG-----LQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLP 235 Query: 79 GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAGAVVPQPGAGVKPGKVPGVGLP 137 G P K G G PG G G+S P G + G+ G+P Sbjct: 236 GPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKGEKGEKGIP 295 Query: 138 GVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKA--PGVGGAFAGIPGV-GPFGGPQPGVP 193 G LPG R P G + G P G K PG+ G F GI G G G P P V Sbjct: 296 G------LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG-FQGIEGQKGDIGLPGPDVF 348 Query: 194 L---GYPIKA-PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV----GPQAA 245 + G I P PG GLP G G G+ G +G G P +GV GPQ Sbjct: 349 IDIDGAVISGNPGDPGVPGLPGLKGD----EGIQGLRGPSGVPGLPALSGVPGALGPQGF 404 Query: 246 AAAAAKAA--AKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAK 302 + GAAG LPG G G PG PG + + + Sbjct: 405 PGLKGDQGNPGRTTIGAAG-LPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQ 463 Query: 303 AAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-GVPGA----GIPVVPGA-------GIP 350 K + G GF GVP G PG G PG G+P + GA G Sbjct: 464 GPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQ 523 Query: 351 G-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAG 409 G A PG+V P + K + G+ G G G GF GV G PG G Sbjct: 524 GPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPG----DRGDSGSQGFR-GVIGEPGKDG 578 Query: 410 VPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA--PGVGVAPGVG 467 VPG+ G+PG+ G G G E + PG+ PG G+ PG PG Sbjct: 579 VPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGL---PGNGLPGLPGPRGLPGDK 635 Query: 468 LAPGVGVAPGVGVAPGVG---VAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPG 523 G+ G+ + G+ + PG GP G + R G G PG Sbjct: 636 GKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS----RGLPGT-PGQPG 690 Query: 524 LGVGVGVPG------LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 577 G PG L G PG G+PGF +PG +PG++G Sbjct: 691 SSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK----------DGLPGMIGSP 740 Query: 578 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGG----LGVPGVG 632 G G G G + GA A + G +G +GL GL GV G LG G Sbjct: 741 GLPGSKGATGDIFGAENGAPGEQGLQGLTGHK-GFLGDSGLPGLKGVHGKPGLLGPKGER 799 Query: 633 GLGGIP-----PAAAAKAAKYGVAARPGFGLSPIFPG 664 G G P P + YG+ + G +P FPG Sbjct: 800 GSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPG 836 Score = 123 bits (309), Expect = 5e-28 Identities = 203/715 (28%), Positives = 257/715 (35%), Gaps = 138/715 (19%) Query: 43 YPALGPGGKPLKPV----PGGLAGAGLGAGLGAFPAVT-FPGALVPGGVADAAAAYKAAK 97 +P G G+P P+ P G G GL FPG L P G K K Sbjct: 42 FPEKGARGRP-GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGP-------KGDK 93 Query: 98 AGAGLGGVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGV 155 G+ G G+ G+ G P+ PG G VG PG P G +PG+ Sbjct: 94 GPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLG 145 Query: 156 LPGVPTGAGVKPKAPGVGGAF------AGIPGVGPFGGPQ--PGVPLGY-PIKAPKLPGG 206 PG+P G K G+F G+PG+ GPQ PG P P P L G Sbjct: 146 PPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGP 205 Query: 207 YGLP---YTTGKLPYGY----GPGGVAGAAGKAGYPTGTG----VG-PQAAAAAAAKAAA 254 G P G + G+ G G G G AG P TG +G P+ + + Sbjct: 206 PGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGP 265 Query: 255 KFGAGAAGV--LPGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAA 309 K G +G PG+G G G G IPG+ G G +G+ K G Sbjct: 266 KGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG-- 323 Query: 310 AGLVPGGPGFGPGVVGVPG-AGVPG----VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAA 363 PG GF G+ G G G+PG + + GA I PG G+PG +PG+ E Sbjct: 324 ---FPGLNGF-QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG--LPGLKGDEGI 377 Query: 364 AKAAAKAAKYGARPGVGVGGIPTY-----GVGAGGFPGF----------GVGVGGIPGVA 408 G R GV G+P +G GFPG +G G+PG Sbjct: 378 ---------QGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRD 428 Query: 409 GVPGVGGVPG--------------VGGVPGVGISPEAQAAAAAKAAK--------YGLVP 446 G+PG G PG G PG+ + K K G VP Sbjct: 429 GLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVP 488 Query: 447 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGP-GGVAAAAKSAAK 504 G PG PG G+ G G G A G APG +GP G K Sbjct: 489 NTG-PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEP 547 Query: 505 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 564 + + Q G+PG G G G PG G+PG +PG Sbjct: 548 ILSTIQ---------GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPG 598 Query: 565 KYGAAVPGVLGGLGALGGVGIPG-GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL---- 618 + G +PG+ G G G G+PG G+ G GP Q GL G+ G+ Sbjct: 599 EKG--LPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPC 656 Query: 619 ---GGLGVGGL----GVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 664 G G G G PG G G+P P + G PG P PG Sbjct: 657 IIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPG 711 Score = 92.8 bits (229), Expect = 9e-19 Identities = 155/530 (29%), Positives = 195/530 (36%), Gaps = 89/530 (16%) Query: 183 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 236 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 52 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 109 Query: 237 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 292 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 110 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 160 Query: 293 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 349 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 161 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 205 Query: 350 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 407 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 206 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 262 Query: 408 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 467 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 263 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 316 Query: 468 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 317 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 372 Query: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 373 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 430 Query: 586 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL---------------- 626 PG GP + + K + F GL G G G LG+ G+ Sbjct: 431 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 490 Query: 627 ------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFGLSPIFPGG 665 G PG GL G+P A+ + G A PG + P+ P G Sbjct: 491 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 539 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 144 bits (362), Expect = 3e-34 Identities = 232/769 (30%), Positives = 277/769 (36%), Gaps = 157/769 (20%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGA-GLGA-------- 67 P R G G PG + G+PG V GP G P P P G GA GL Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEV--GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTR 598 Query: 68 ------GLGAFPA----VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGA 117 GL FP G P GVA + K G G PGV G V Sbjct: 599 GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP----QGEKGDVGPAGPPGVPGSVVQQEG 654 Query: 118 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPK-----APG 171 + + GA PG G PG PGAR P G G P G++ K PG Sbjct: 655 LKGEQGA---PGPRGHQGAPGP------PGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705 Query: 172 VGGAFA-----GIPGV-GPFG-GPQPGVP--LGYPIKAPKLPGGYGLPYTTGK--LPYGY 220 + G G PGV GP G G PG+P +G+P K P PG G P G P Sbjct: 706 IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK-PGPPGPTGPPGKDGPNGPPGPP 764 Query: 221 GPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV--LPGV---------- 267 G G G G+ G P G+ G A + K AG G PGV Sbjct: 765 GTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 824 Query: 268 GGAGVPGV-----------PGAIPGIGGIAGVGTPAAAAAAAAAAKAAK----------- 305 G G+PG+ P PG+ G + TP K K Sbjct: 825 GELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGL 884 Query: 306 YGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPG-AGIPG-AAVPGVVSPEA 362 G L P GP PG G GA G PG AG P PG G PG + PG V Sbjct: 885 QGRPGELGPQGPTGPPGAKGQEGAHGAPG----AAGNPGAPGHVGAPGPSGPPGSVGAPG 940 Query: 363 AAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG--GVPGVG 420 K + G + G G P VG G P G PG+ G PG G G PG+ Sbjct: 941 LRGTPGKDGERGEKGAAGEEGSPG-PVGPRGDP-------GAPGLPGPPGKGKDGEPGLR 992 Query: 421 GVPGVGISPEAQAAAAAK-------AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA--PG 471 G PG+ P AA K A V G APG+ +PG PG+G+A PG Sbjct: 993 GSPGLP-GPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPG 1051 Query: 472 VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAK--VAAKAQLRAAAGLG------- 518 PG +PG PG GP G A + + K L + G Sbjct: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111 Query: 519 -------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 565 G+PG GVPG G G AG PG PG +A + ++ Sbjct: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IAGPQGSQ 1170 Query: 566 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL----GGL 621 G +G G G G+PG + G A A A G+ G+ G G Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230 Query: 622 GVGGL-GVPGVGGLGGI-----PPAAAAKAAKYGVAARPGFGLSPIFPG 664 G GL G+PG G G PP KA + G+ G P F G Sbjct: 1231 GPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 1279 Score = 120 bits (300), Expect = 5e-27 Identities = 203/705 (28%), Positives = 240/705 (34%), Gaps = 135/705 (19%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL 81 +P PG V P G PG V P L G P K G GA G PG + Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGL--RGTPGKDGERGEKGAAGEEG--------SPGPV 966 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQP-GAGVKPGKVPGVGLPGVY 140 P G D A G G G PG+ G S G +P P G GKV G Sbjct: 967 GPRG--DPGAPGLPGPPGKGKDGEPGLRG---SPG--LPGPLGTKAACGKVRG------S 1013 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 L G G PG+P G + G PG+G G P P P Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSR-----------GDPGIGVAGPPGPSGP------- 1055 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG----------VGPQAAAAAAA 250 PG G P + G LP GP G AG G G P G + P A Sbjct: 1056 ---PGDKGSPGSRG-LPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111 Query: 251 KAAAKFGAGAAGV--LPGV-GGAGVPGVPG-----------AIPGIGGIAGVGTPAAAAA 296 G G+ LPG G GVPG PG PG+ G G+ P + Sbjct: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171 Query: 297 AAAAAKAAKYGAAAGLVPGGPGF--GPGVVGVPGA-GVPGVGVPGAGIPVVPG-AGIPG- 351 A G PG PGF PG G PGA G+ G P GI PG G PG Sbjct: 1172 ERGADGEVGQKGDQG-HPGVPGFMGPPGNPGPPGADGIAGAAGP-PGIQGSPGKEGPPGP 1229 Query: 352 ---AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF--GVGVGGIPG 406 + +PG+ E K G G G+P GA G PGF G G PG Sbjct: 1230 QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG-PEGARGPPGFKGHTGDSGAPG 1288 Query: 407 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 466 G G G+PG G+PG + + PG +PG PG PG Sbjct: 1289 PRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG--PPGKNGSPGSPGEPGPSGTPGQ 1346 Query: 467 GLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 526 + G +PG+ G PG PG K V K G PG Sbjct: 1347 KGSKGENGSPGLPGFLGPRGPPG-EPGEKGVPGKEG--VPGK----------PGEPGFKG 1393 Query: 527 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 586 G PG+ G PG G G PG +PG +PG G +G G G P Sbjct: 1394 ERGDPGIKGDKGPPG---GKGQPGDPGIPGH-KGHTGLMGPQGLPGENGPVGPPGPPGQP 1449 Query: 587 G--GVVGAGPA------------------------AAAAAAKAAAKAAQFGLVGAAGLGG 620 G G+ G P+ A A + + G G G G Sbjct: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509 Query: 621 L--GVGGLGVPGVGGLGGI-----PPAAAAKAAKYGVAARPGFGL 658 L G +G PG G GG+ P + G PG GL Sbjct: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGL 1554 Score = 110 bits (274), Expect = 6e-24 Identities = 202/700 (28%), Positives = 233/700 (33%), Gaps = 111/700 (15%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGV 86 G PG + P G PG P GP GK PG GL LG A G + G Sbjct: 961 GSPGPVGPRGDPGAPGLP--GPPGKGKDGEPGLRGSPGLPGPLGTKAAC---GKV--RGS 1013 Query: 87 ADAAAAYKAAKAGAGLGGVPGVGGLGVSAG-AVVPQPGAGVKPGKVPGVGLPGVYPGGVL 145 + A + K G G+PG G G V PG PG G G L Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG------L 1067 Query: 146 PGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP----------GVPLG 195 PG FPG P P G P PG G G PG+ P P G Sbjct: 1068 PG--FPG----PQGPAGRDGAPGNPGERGP-PGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120 Query: 196 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 255 P P LPG G GK P G G G AG G P G+ + A + Sbjct: 1121 PP-GLPGLPGFKGDKGVPGK-PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178 Query: 256 FGAGAAGVLPGVGG-AGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL-- 312 G PGV G G PG PG PG GIAG P + +GL Sbjct: 1179 VGQKGDQGHPGVPGFMGPPGNPGP-PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 313 VPG-----------GPGFGPGVVGVPGA-------GVPGV-------GVPG----AGIPV 343 +PG GP PG G PG G PG G PG +G Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297 Query: 344 VPGA-GIPG----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG-----G 393 +PG G+PG G P+ K G+ G G P G G Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357 Query: 394 FPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-VPGVGV 450 PGF G G PG GVPG GVPG G PG K G PG Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417 Query: 451 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 510 PG G+ G+ G PG PG G P ++ + + Sbjct: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 1477 Query: 511 LRAAAGLG-------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA 557 R A L G PG G+PG G PG G+ G + P Sbjct: 1478 TRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG-PSGPIG 1536 Query: 558 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 617 + AK PGV G G +G GIPG G A+ GL G G Sbjct: 1537 PKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPG-------------YAKDGLPGIPG 1582 Query: 618 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY--GVAARPG 655 G G G PG+ G G P Y +AARPG Sbjct: 1583 PQG-ETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621 Score = 107 bits (268), Expect = 3e-23 Identities = 185/649 (28%), Positives = 224/649 (34%), Gaps = 116/649 (17%) Query: 28 GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGAL--VPGG 85 G PG IPG PG P +G G P P G G+ GL FP P PG Sbjct: 1028 GAPG-IPGS-PGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085 Query: 86 VADAAAAYKAAKAGA-------------------GLGGVPGVGGLGVSAGAVVPQPGAGV 126 + K + G G+PG+ G G V +PG Sbjct: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG-VPGKPGREG 1144 Query: 127 KPGKVPGVGLPGVY--PGGVLP----GAR-------------FPGVGVLPGVPTGAGVKP 167 GK G PG+ PG P G R PGV G P G P Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG-PP 1203 Query: 168 KAPGVGGAFAGIPGV----GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPG 223 A G+ GA AG PG+ G G P P P G P +PG G GK GP Sbjct: 1204 GADGIAGA-AGPPGIQGSPGKEGPPGPQGPSGLP----GIPGEEGKEGRDGKP----GPP 1254 Query: 224 GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIG 283 G G AG+ G P GP+ A +GA G G G+PG G +PG Sbjct: 1255 GEPGKAGEPGLP-----GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG-LPGKD 1308 Query: 284 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----------GVPG 333 G G P K G+ PG PG PG G PG G+PG Sbjct: 1309 GDTGPTGPQGPQGPRGPP--GKNGS-----PGSPG-EPGPSGTPGQKGSKGENGSPGLPG 1360 Query: 334 V----GVPGA-GIPVVPGA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386 G PG G VPG G+PG PG G + G GIP Sbjct: 1361 FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIP- 1419 Query: 387 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLV 445 G G G +G G+PG G G G PG G PG+ G SP + + G Sbjct: 1420 ---GHKGHTGL-MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 1475 Query: 446 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAK 504 +A + P + G PG PG PG G G G + Sbjct: 1476 LETRLAYLLAQMPPAYMKSSQG-RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534 Query: 505 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 564 + K + A GA GL +G PG+ G PG G+PG Sbjct: 1535 IGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-GLPG-------------- 1579 Query: 565 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 613 +PG G G G G+PG G + A A+ AA+ G V Sbjct: 1580 -----IPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623 Score = 105 bits (261), Expect = 2e-22 Identities = 158/548 (28%), Positives = 182/548 (33%), Gaps = 102/548 (18%) Query: 205 GGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA-----G 259 G GLP G + G G GA G G G+GP K + G Sbjct: 490 GPMGLPGPKGDI----GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDG 545 Query: 260 AAGVLPGVGGAGVPGVPGAI--------PGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA 310 + G+ G G PG+PG + PG+ G G VG P + G Sbjct: 546 SKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGER- 604 Query: 311 GL--VPGGPGFG-----PGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAA 363 GL PG PG PG GV G V AG P VPG+ + + G Sbjct: 605 GLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP 664 Query: 364 AKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 GAR +G G P G G G +G GIPG+ G+ G G PGV G Sbjct: 665 RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKG-DMGPPGIPGLLGLQGPPGPPGVPG 723 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 481 PG G SP PG PG PG G PG PG Sbjct: 724 PPGPGGSPGLPGEIG--------FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGE 775 Query: 482 PGVGVAPG----IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA--------------GIPG 523 G+ PG IG G+A +A L A G G+PG Sbjct: 776 DGLPGKPGLRGEIGEQGLAGRPGE----KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 831 Query: 524 LGVGVGVPGLGVGAGVPGL-GVGA------------------------GVPGFGAVPGAL 558 L G G AG PGL G + G PG PG L Sbjct: 832 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891 Query: 559 A--------AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 610 AK + PG G GA G VG PG G A K + Sbjct: 892 GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951 Query: 611 GLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACL 668 G GAAG G VG G PG GL G PP G PG SP PG Sbjct: 952 GEKGAAGEEGSPGPVGPRGDPGAPGLPG-PPGK-------GKDGEPGLRGSPGLPGPLGT 1003 Query: 669 GKACGRKR 676 ACG+ R Sbjct: 1004 KAACGKVR 1011 Score = 84.0 bits (206), Expect = 4e-16 Identities = 137/462 (29%), Positives = 165/462 (35%), Gaps = 77/462 (16%) Query: 261 AGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAA----AAAAAAKAAKYGAAAGL-VPG 315 AG +G AG G+PG IG I VG P + G L +PG Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPG 539 Query: 316 GPG--FGPGVVGVPG----AGVPG-VGVPG----AGIPVVPG-AGIPG------------ 351 PG G+ G PG G+PG VG+ G G+P PG G PG Sbjct: 540 PPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRG 599 Query: 352 ----------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 401 PG + + A G + VG G P G PG V Sbjct: 600 EKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP-------GVPGSVVQQ 652 Query: 402 GGIPGVAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGL--------VPGVGVA 451 G+ G G PG G G G PG I PE + G +PG+ Sbjct: 653 EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGL 712 Query: 452 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQ 510 G PGV PG G +PG+ PG PG PG GP G K + Sbjct: 713 QGPPGPPGVPGPPGPGGSPGL---PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769 Query: 511 --LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKY 566 R GL G PGL +G GL AG PG AG+PG PG + K Sbjct: 770 PGERGEDGL-PGKPGLRGEIGEQGL---AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Query: 567 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGG 625 +PG+ G G G G P G G P + + G G G GL G G Sbjct: 826 ELGLPGLKGDRGEKGEAG-PAGPPGL-PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883 Query: 626 L-GVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIFPG 664 L G PG G G PP A + +G PG +P PG Sbjct: 884 LQGRPGELGPQGPTGPPGAKGQEGAHGA---PGAAGNPGAPG 922 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 143 bits (361), Expect = 5e-34 Identities = 167/524 (31%), Positives = 200/524 (38%), Gaps = 38/524 (7%) Query: 117 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAF 176 AV + G PG G PG PG PG+ PG+P G P A G G Sbjct: 54 AVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG--PSAVGKPGV- 110 Query: 177 AGIPGV----GPFGGPQPGVPLGYPIKAPK-LPGGYGLPYTTG-KLPYGYGPGGVAGAAG 230 G+PG GP+G P G P P+ PG G+P G +P G G GA G Sbjct: 111 PGLPGKPGERGPYGPKGDVGPAGLP--GPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168 Query: 231 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 290 G+P G P K +GA G+ G P P PG+G G Sbjct: 169 PRGFPGEKG-APGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGV 227 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG-VGVPGAGIPVVPGA-G 348 P + G + P GP PG G G G PG G PG P +PG G Sbjct: 228 PGQPGIKGDRGFPGEMGP---IGPPGPQGPPGERGPEGIGKPGAAGAPGQ--PGIPGTKG 282 Query: 349 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 408 +PGA PG+ P K G + G G+P G GA G G G+ G PG+ Sbjct: 283 LPGA--PGIAGP-PGPPGFGKPGLPGLKGERGPAGLPG-GPGAKGEQG-PAGLPGKPGLT 337 Query: 409 GVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 467 G PG G G G+PG G+ A A Y G +PG PG PG+ Sbjct: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397 Query: 468 LAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 526 G PG PGVG PG+ GP G A AK +A R A GIPG Sbjct: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVG-PAGAKGMPGHNGEAGPRGA----PGIPGTRG 452 Query: 527 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 +G P G+PG G PG PG A A K PG G G G G+ Sbjct: 453 PIGPP------GIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGL 506 Query: 586 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 629 PG GP A + KA Q + L G G+P Sbjct: 507 PGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550 Score = 123 bits (308), Expect = 6e-28 Identities = 161/530 (30%), Positives = 192/530 (36%), Gaps = 110/530 (20%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P+ P G PG P G PG Y + G G+P P P G + G G+ P PG Sbjct: 67 PAGPRGHPG--PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGK-PGVPGLPGK--PGERG 121 Query: 83 PGGVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY 140 P G A + G G+PG G+ V PG KPG+ G PG Sbjct: 122 PYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISV--------PG---KPGQQGPTGAPG-- 168 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPK----APGVGGAFAGIPG----VGPFGGP---- 188 P G FPG PGVP G K + APG G G+PG GP G P Sbjct: 169 PRG------FPGEKGAPGVPGMNGQKGEMGYGAPGRPGE-RGLPGPQGPTGPSGPPGVGK 221 Query: 189 --------QPGVP--LGYPIKAPKL--PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 236 QPG+ G+P + + PG G P G P G G G AGA G+ G P Sbjct: 222 RGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG--PEGIGKPGAAGAPGQPGIPG 279 Query: 237 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 296 G+ P A A PG G G+PG+ G G G G Sbjct: 280 TKGL-PGAPGIAGPPGP-----------PGFGKPGLPGLKGERGPAGLPGGPGAKGEQGP 327 Query: 297 AAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----------AGVPGV----GVPGA--- 339 A K G + P GP PG G+PG AG PG G PG+ Sbjct: 328 AGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGK 387 Query: 340 -GIPVVPG-------AGIPG-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI 384 G P PG G+PG PG+ P A A G G GI Sbjct: 388 PGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGI 447 Query: 385 P-TYG-VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 442 P T G +G G PGF PG G PG G PG G+ G++ + Sbjct: 448 PGTRGPIGPPGIPGF-------PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGH 500 Query: 443 GLVPGVGVAPGVGVAPGVGVAP----GVGLAPGVGVAPGVGVAPGVGVAP 488 PG+ PG PG V P G P + P V GV P Sbjct: 501 SGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550 Score = 111 bits (277), Expect = 2e-24 Identities = 148/482 (30%), Positives = 176/482 (36%), Gaps = 86/482 (17%) Query: 183 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY----GPGGVAGAAGKAGYPTGT 238 G F + +P G P + +PYT G G G AG G+P Sbjct: 18 GVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP--- 74 Query: 239 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 298 GP +G G PG G G+ G PG +PG G + VG P Sbjct: 75 --GP---------------SGPPGK-PGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPG 115 Query: 299 AAAKAAKYGAAAGLVPGG---PGFGPGVVGVPG-AGVPGVGVPGAGIPV-VPGA-GIPGA 352 + YG + P G P PG G+PG AG+ G PG P PG G PG Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175 Query: 353 -AVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPGFGV-GVGGIPGV 407 PGV YGA RPG G+ G P G G PG G G G+PG Sbjct: 176 KGAPGVPGMNGQKGEMG----YGAPGRPGERGLPG-PQGPTGPSGPPGVGKRGENGVPGQ 230 Query: 408 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 467 G+ G G PG G G P Q + + G+G PG APG PG Sbjct: 231 PGIKGDRGFPGEMGPIG---PPGPQGPPGERGPE-----GIG-KPGAAGAPGQPGIPGTK 281 Query: 468 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG 527 PG APG+ PG PG G G+ L+ G AG+PG G Sbjct: 282 GLPG---APGIAGPPG---PPGFGKPGLPG-------------LKGERG-PAGLPG---G 318 Query: 528 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGI 585 G G AG+PG PG PG + K +PG G G G G Sbjct: 319 PGAKGEQGPAGLPGK------PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372 Query: 586 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 645 PG G + K GL G G GL G G PGVGG G+P Sbjct: 373 PGAKGERGSPGSDGKPGYPGKP---GLDGPKGNPGLP-GPKGDPGVGGPPGLPGPVGPAG 428 Query: 646 AK 647 AK Sbjct: 429 AK 430 Score = 70.1 bits (170), Expect = 6e-12 Identities = 93/301 (30%), Positives = 110/301 (36%), Gaps = 67/301 (22%) Query: 400 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 459 G G PG G G G PG G PG YG PG+ PG+ PG Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPG--------------KPGYG-SPGLQGEPGLPGPPG 101 Query: 460 VGVA--PGVGLAPG-------------VGVA--PGVGVAPGVGVAPGI-GPGGVAAAAKS 501 PGV PG VG A PG PG PGI GP G++ K Sbjct: 102 PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPG---PPGIPGPAGISVPGKP 158 Query: 502 AAK--VAAKAQLRAAAGLGA-GIPGLG-----VGVGVPGLGVGAGVPGL--------GVG 545 + A GA G+PG+ +G G PG G+PG G Sbjct: 159 GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218 Query: 546 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKA 603 G G VPG K PG +G +G G G PG G G G AA A Sbjct: 219 VGKRGENGVPG----QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQ 274 Query: 604 AAKAAQFGLVGAAGLGG-LGVGGLGVPGVGGL------GGIP--PAAAAKAAKYGVAARP 654 GL GA G+ G G G G PG+ GL G+P P A + G+ +P Sbjct: 275 PGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP 334 Query: 655 G 655 G Sbjct: 335 G 335 Score = 48.5 bits (114), Expect = 2e-05 Identities = 66/226 (29%), Positives = 77/226 (34%), Gaps = 45/226 (19%) Query: 445 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAA 503 V G PG G PG PG PG G +PG+ PG+ GP G +A K Sbjct: 55 VRGEQGTPGPPGPAGPRGHPGPSGPPG---KPGYG-SPGLQGEPGLPGPPGPSAVGKPGV 110 Query: 504 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 563 G+PG G G G GL G PG +PG + Sbjct: 111 P---------------GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP 155 Query: 564 AKYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 618 K PG G GA G G PG GV G A + + GL G G Sbjct: 156 GK-----PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQG- 209 Query: 619 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G G PGVG K + GV +PG FPG Sbjct: 210 ---PTGPSGPPGVG-----------KRGENGVPGQPGIKGDRGFPG 241 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 139 bits (351), Expect = 7e-33 Identities = 213/673 (31%), Positives = 249/673 (36%), Gaps = 106/673 (15%) Query: 26 PGGVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPG 84 P G PG P G PG V G G P P G AG +GL P T P PG Sbjct: 2163 PEGKPGLQGPRGPPGPV--GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP----PG 2216 Query: 85 -GVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPG- 142 G+ A GL G PG GL V PQ G+ PG+V G PG PG Sbjct: 2217 RGLTGPTGA-------VGLPGPPGPSGL------VGPQGSPGL-PGQVGETGKPGA-PGR 2261 Query: 143 ----GVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGG-AFAGIPGVGPFGGPQPGVPLG 195 G PGV PG+P G K P G G A G+PG G PG G Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA-PGGLAG 2320 Query: 196 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 255 + P G GLP GP G G AG+AG P G Q A Sbjct: 2321 DLVGEPGAKGDRGLP----------GPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370 Query: 256 FGAGAAGVL-----PGV-GGAGVPGVPGAIPGIGGIAG-------VGTPAAAAAAAAAAK 302 G G G PGV G G+PG+PGA PG+ G G +G P + A Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGA-PGVVGFPGQTGPRGEMGQPGPSGERGLAGP 2429 Query: 303 AAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPGVGVPGA----GIPVVPGA-GIP 350 + G L P GP PG VG PGA G PGVG+PG G P + G G P Sbjct: 2430 PGREGIPGPLGPPGP---PGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP 2486 Query: 351 GAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAG 409 G P G+ P + + G+ G G +G G P G G G G Sbjct: 2487 GQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG-PRGAKGDMGERGPRG 2545 Query: 410 VPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 469 + G G G G PG + GL PG+ G PG PG + Sbjct: 2546 LDGDKGPRGDNGDPG----DKGSKGEPGDKGSAGL-PGLRGLLGPQGQPGAAGIPGDPGS 2600 Query: 470 PGVGVAPGV-GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA--GIPGLGV 526 PG PG+ G VG +GP G+ + ++ A GL G G Sbjct: 2601 PGKDGVPGIRGEKGDVGF---MGPRGLKG----------ERGVKGACGLDGEKGDKGEAG 2647 Query: 527 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAAVPGVLGGLGALGGVG 584 G PGL AG G GVPG PG L K + PG G G G G Sbjct: 2648 PPGRPGL---AGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERG 2704 Query: 585 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG--VGGLGGIPPAAA 642 PG GP+ +A G G GL G G G PG V G G+P A Sbjct: 2705 TPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG-QKGERGPPGERVVGAPGVPGAPG 2763 Query: 643 AKAAKYGVAARPG 655 + G RPG Sbjct: 2764 ER----GEQGRPG 2772 Score = 134 bits (336), Expect = 4e-31 Identities = 214/684 (31%), Positives = 252/684 (36%), Gaps = 134/684 (19%) Query: 28 GVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVA 87 G PG P G PG ALG G P P GLAG G+ P GGV Sbjct: 2009 GDPG--PQGPPG----LALGERGPP---GPSGLAGEPGKPGIPGLPGRA-------GGVG 2052 Query: 88 DAAAAYKAAKAGA-------GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY 140 +A + + G G G PG+ G PG PG V PG Sbjct: 2053 EAGRPGERGERGEKGERGEQGRDGPPGLPGT----------PGPPGPPGPKVSVDEPG-- 2100 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGV-GPFGGPQPGVPLGYP 197 PG L G + P PG+ GA +P + G G G+PG+ G G P P G P Sbjct: 2101 PG--LSGEQGP-----PGLK-GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNP 2152 Query: 198 IKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAK 251 LPG G+ GK L GP G G G G P G+ GPQ + + Sbjct: 2153 ----GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208 Query: 252 AAAKFGAGAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG-VGTPAAAAAAAAAAK 302 + G G+ G G+PG PG PG+ G G G P A A+ K Sbjct: 2209 PG-ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGK 2267 Query: 303 AAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG---VGVPGA-GIPVVPG------AG 348 G+ VPG PG PG VG G G PG VG+PGA G PG G Sbjct: 2268 DGDRGSPG--VPGSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVG 2324 Query: 349 IPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GVGVGGIPG 406 PGA G+ P A +A + G G G P G GF G GVGV G PG Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP----GPKGFKGDPGVGVPGSPG 2380 Query: 407 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 466 G PGV G G+ G+PG PGV PG G PG Sbjct: 2381 PPGPPGVKGDLGLPGLPG--------------------APGVVGFPGQTGPRGEMGQPGP 2420 Query: 467 GLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 526 G+ PG PG PG PG V S K G G+PG Sbjct: 2421 SGERGLAGPPGREGIPGPLGPPG-PPGSVGPPGASGLK-------GDKGDPGVGLPGPRG 2472 Query: 527 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPG--------ALAAAKAAKYGAAV----PGVL 574 G PG+ G PG G+ G G A K K +AV PG Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR 2532 Query: 575 GGLGALGGVGIPGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 633 G G +G G P G+ G GP + G G+AGL GL G LG G G Sbjct: 2533 GAKGDMGERG-PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR-GLLGPQGQPG 2590 Query: 634 LGGIP--PAAAAKAAKYGVAARPG 655 GIP P + K G+ G Sbjct: 2591 AAGIPGDPGSPGKDGVPGIRGEKG 2614 Score = 130 bits (326), Expect = 5e-30 Identities = 215/720 (29%), Positives = 255/720 (35%), Gaps = 141/720 (19%) Query: 23 PSRPGGVPG--AIPG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFP 78 PS G PG IPG G GGV G G+P + G G G P + P Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGV-----GEAGRPGERGERGEKGERGEQGRDGPPGL--P 2081 Query: 79 GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPG 138 G PG + G GL G G GL + G +PG+ G G+PG Sbjct: 2082 GT--PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKG----EPGSNGDQGPKGDRGVPG 2135 Query: 139 VYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGP-QPGVPLG 195 + PG R G LPG AG + K PG+ G G PG VG G P PG P Sbjct: 2136 IKGDRGEPGPRGQDGNPGLPGERGMAGPEGK-PGLQGP-RGPPGPVGGHGDPGPPGAPGL 2193 Query: 196 YPIKAPKLPGGY-GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAA------AA 247 P+ P G G P TG P G G G GA G G P +G VGPQ + Sbjct: 2194 AGPAGPQGPSGLKGEPGETG--PPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVG 2251 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKA 303 K A GA+G G GVPG PG +PG G G G P A AK Sbjct: 2252 ETGKPGAPGRDGASGKDGDRGSPGVPGSPG-LPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310 Query: 304 AKYGAAAGLV------------------------------PGGPGFGPGVVGVPGA---- 329 K GA GL PG PG G G PG Sbjct: 2311 EK-GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPG-EDGQKGAPGPKGFK 2368 Query: 330 GVPGVGVPGA-GIPVVPGA-------GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGV 381 G PGVGVPG+ G P PG G+PGA PGVV + + G G+ Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA--PGVVGFPGQTGPRGEMGQPGPSGERGL 2426 Query: 382 GGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI-SPEAQAAAAAKAA 440 G P G G PG +G G PG G PG G+ G G PGVG+ P + Sbjct: 2427 AGPP----GREGIPG-PLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG 2481 Query: 441 KYGLVPGVGVAPGVGVAPGV-------GVAPGVGLAPGVGVAPGVGVAPGVGVAPGI--- 490 + G PG G+ PG G GL G + + PG A G Sbjct: 2482 EDGR-PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGE 2540 Query: 491 -GPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVG 545 GP G+ + G AG+PGL +G G AG+PG Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPG---D 2597 Query: 546 AGVPGFGAVPG--------------ALAAAKAAKYGAAV---------------PGVLGG 576 G PG VPG L + K + PG+ G Sbjct: 2598 PGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGH 2657 Query: 577 LGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 636 G +G G+PG G Q G G G G G PG+GG G Sbjct: 2658 KGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQG----EKGERGTPGIGGFPG 2713 Score = 122 bits (306), Expect = 1e-27 Identities = 207/734 (28%), Positives = 255/734 (34%), Gaps = 138/734 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPA-LGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF---- 77 P+ P G G P G+ P GP G P P GL G G P Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620 Query: 78 ---PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 134 PG + P G D K + G G+PG G GA PG G+ Sbjct: 1621 PGPPGPVGPRG-RDGEVGEKGDEGPPGDPGLPGKAGERGLRGA----PGVRGPVGEKGDQ 1675 Query: 135 GLPGVYPGGVLPGARFP----GVGVLPGVP-----TGAGVKPKA---------------- 169 G PG PG+ P G PG P TG G + K Sbjct: 1676 GDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGD 1735 Query: 170 PGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-------LPGGYGLPYTTGKLPYGYG 221 PG+ GA G G+ F GP PG P G P ++ P PG G GK P G Sbjct: 1736 PGLPGA-PGERGIEGFRGP-PG-PQGDPGVRGPAGEKGDRGPPGLDGRSGLDGK-PGAAG 1791 Query: 222 PGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVP 276 P G GAAGKAG P G+ G Q + G G PG+ G G PG P Sbjct: 1792 PSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK-PGLNGKNGEPGDP 1850 Query: 277 GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV-- 334 G G G A+ + GA L P GP PG VG PG G PGV Sbjct: 1851 GED---GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPG 1907 Query: 335 -----------------GVPG-AGIPVVPG-----------AGIPGAAVPGVVS------ 359 G+PG G+ PG AGI +A+ +V Sbjct: 1908 GTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESS 1967 Query: 360 ------PEAAAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGFGVGVGGIP 405 PE + + G G G P G G PG +G G P Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027 Query: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 465 G +G+ G G PG+ G+PG +A +A + G G G G PG Sbjct: 2028 GPSGLAGEPGKPGIPGLPG-------RAGGVGEAGRPG-ERGERGEKGERGEQGRDGPPG 2079 Query: 466 VGLAPGVGVAPGVGVA---PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 522 + PG PG V+ PG G++ GP G+ A + G+P Sbjct: 2080 LPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG-----DRGVP 2134 Query: 523 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 582 G+ G PG G PGL G+ G PG PG +GG G G Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP-------RGPPGPVGGHGDPGP 2187 Query: 583 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-GVPGVGGLGGIPPAA 641 G PG AGPA + + + G G G G GL G PG GL G P + Sbjct: 2188 PGAPG---LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVG-PQGS 2243 Query: 642 AAKAAKYGVAARPG 655 + G +PG Sbjct: 2244 PGLPGQVGETGKPG 2257 Score = 121 bits (303), Expect = 2e-27 Identities = 205/663 (30%), Positives = 237/663 (35%), Gaps = 113/663 (17%) Query: 44 PALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 103 P P G+ +P GL G G P T GA P G +A A K + G Sbjct: 1248 PVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRT--GAPGPQGPPGSATA-KGERGFPGAD 1304 Query: 104 GVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA 163 G PG G + G PGA PG GLPG P G PG R P G Sbjct: 1305 GRPGSPGRAGNPGT----PGA---PGLKGSPGLPG--PRGD-PGERGP---------RGP 1345 Query: 164 GVKPKAPG--VGGAFAGIPG----VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL- 216 +P APG +GG G+PG GP G P P PLG P P+ P G LP T K Sbjct: 1346 KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP--GPRGPPG--LPGTAMKGD 1401 Query: 217 --------PYGYGPGGVA-GAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGA--GAAGVLP 265 P G G GG+A G G G P G PQ K K + GA G LP Sbjct: 1402 KGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG--PQGPVGPPGKKGEKGDSEDGAPG-LP 1458 Query: 266 G----------------VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 G +G G G PG + G G P A + A + GA Sbjct: 1459 GQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAK 1518 Query: 310 AGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPG-AAVPGVVSPEAAAKAAA 368 P GP G G PG G P V G + G G V P A Sbjct: 1519 GPEGPPGPTGRQGEKGEPGR---------PGDPAVVGPAVAGPKGEKGDVGPAGPRGATG 1569 Query: 369 KAAKYGARPGVGVGGIPTYGVGAGGFPG----FGV-GVGGIPGVAGVPGVGGVPGVGGVP 423 + G PG+ + G P G G PG G+ G G PG +G PG G PG G P Sbjct: 1570 VQGERGP-PGLVLPGDP----GPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP 1624 Query: 424 GVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG 483 G + P + + G PG PG G+ APGV G G G Sbjct: 1625 G-PVGPRGRDGEVGEKGDEG-PPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682 Query: 484 VGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA---GIPGLGVGVGVPGLGVGAGV 539 +PG GP G G GA G PG G G G+ Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVD----TGPGAREKGEPGDRGQEGPRGPKGDPGL 1738 Query: 540 PGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVGAGP 594 PG G+ GF PG PGV G G G G PG G+ G Sbjct: 1739 PGAPGERGIEGFRGPPGP----------QGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPG 1788 Query: 595 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAA 652 AA + AA A G G GL GL G G+PG G G+P P K G Sbjct: 1789 AAGPSGPNGAAGKA--GDPGRDGLPGLR-GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845 Query: 653 RPG 655 PG Sbjct: 1846 EPG 1848 Score = 112 bits (281), Expect = 9e-25 Identities = 217/742 (29%), Positives = 255/742 (34%), Gaps = 133/742 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P P G PGA PG V GG GPG K PG G LG PG Sbjct: 1342 PRGPKGEPGA-PGQVIGGE-----GPGLPGRKGDPGPSGPPGPRGPLGD------PGPRG 1389 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY-- 140 P G+ A K K G G PG G G++ G PG PG VG PG Sbjct: 1390 PPGLP--GTAMKGDKGDRGERGPPGPGEGGIAPGEP-GLPGLPGSPGPQGPVGPPGKKGE 1446 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYP 197 G GA PG+ PG P G + P A G G G PG +G G P G P Sbjct: 1447 KGDSEDGA--PGLPGQPGSPGEQGPRGPPGAIGPKGD-RGFPGPLGEAGEKGERGPPG-P 1502 Query: 198 IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFG 257 + LPG G P G GP G G G+ G P G A A K Sbjct: 1503 AGSRGLPGVAGRPGAKGP----EGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGD 1558 Query: 258 AGAAGVLPGVGGAGVPGVPGAI----PGIGGIAG----VGTPAAAAAAAAAAKAAKYGAA 309 G AG G G G PG + PG G G +G A + + G Sbjct: 1559 VGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDP 1618 Query: 310 AGLVPGGPGFGP----------GVVGVPG-AGVPGV-------GVPGAGIPVV------- 344 P GP GP G G PG G+PG G PG PV Sbjct: 1619 GRPGPPGP-VGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGD 1677 Query: 345 PGA----GIPGAA-------VPGVVSPEAAAKAAAKAAKYGARPG----------VGVGG 383 PG G PG++ PG P A+ PG G G Sbjct: 1678 PGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPG 1737 Query: 384 IPTYGVGAGGFPGF----------GV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ 432 +P G G GF GV G G G G PG+ G G+ G PG P Sbjct: 1738 LPG-APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAA-GPSGP 1795 Query: 433 AAAAAKAAKYGL--VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI 490 AA KA G +PG+ G+ PG PG+ PG PG+ G PG Sbjct: 1796 NGAAGKAGDPGRDGLPGLRGEQGL---PGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGE 1852 Query: 491 ----GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVG 545 G G + A+ + K + A LG G PGL VG PG G GVPG G G Sbjct: 1853 DGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF-PGVPG-GTG 1910 Query: 546 A-------------GVPGF-------GAVPGALAAAKAAKYGA-AVPGVLGGLGALGGVG 584 G+PG G+VP + A A A+ ++ G Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSF 1970 Query: 585 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 644 +P GP + K G G GL G G PG G G+ Sbjct: 1971 LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG----DRGDPGPQGPPGLALGERGP 2026 Query: 645 AAKYGVAARPGFGLSPIFPGGA 666 G+A PG P PG A Sbjct: 2027 PGPSGLAGEPGKPGIPGLPGRA 2048 Score = 103 bits (256), Expect = 7e-22 Identities = 179/574 (31%), Positives = 207/574 (36%), Gaps = 146/574 (25%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPG 79 P P G+ G PG G PG G G P P P GL G GL G PG Sbjct: 2199 PQGPSGLKGE-PGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG 2257 Query: 80 ALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----------LGVSAGAVVPQPGA-GVK- 127 A PG D A+ + G+ G PG+ G G AVV PGA G K Sbjct: 2258 A--PG--RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313 Query: 128 -PGKVPG--VGLPGVYPGGVLPGARFP----GVGVLPGVPTGAGVKPKAPGVGGAFAGIP 180 PG + G VG PG LPG R G PG P G K APG G F G P Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG-APGPKG-FKGDP 2371 Query: 181 GVGPFGGPQPGVP------LGYPIKAPKLPGGYGLPYTTGKL-----PYGYGPGGVAGAA 229 GVG G P P P LG P P PG G P TG P G G+AG Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLP-GLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430 Query: 230 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPG--AIPGIGG 284 G+ G P G GP + + K G GV LPG G G PG+ G PG G Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEG 2490 Query: 285 IAGVGTPAAAAA--------AAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------- 328 G+ P + +A K K +A L P GP G +G G Sbjct: 2491 PRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDK 2550 Query: 329 -----------------------AGVPGV-------GVPGA-GIPVVPGA----GIPGAA 353 AG+PG+ G PGA GIP PG+ G+PG Sbjct: 2551 GPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610 Query: 354 VP----GVVSP-----EAAAKAAA-----KAAKYGA----RPGV-------GVGGIPTYG 388 G + P E K A K K A RPG+ G G+P Sbjct: 2611 GEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQS 2670 Query: 389 --------VGAGGFPGFG-----------VGVGGIPGVAGVPGVGGVPGVGGVPGV--GI 427 +G G GF G G PG+ G PG G G G PG + Sbjct: 2671 GAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSV 2730 Query: 428 SPEAQAAAAAKAAKYGLVPGVGV--APGVGVAPG 459 P + + G PG V APGV APG Sbjct: 2731 GPRGPEGLQGQKGERG-PPGERVVGAPGVPGAPG 2763 Score = 89.4 bits (220), Expect = 1e-17 Identities = 153/535 (28%), Positives = 180/535 (33%), Gaps = 163/535 (30%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPALG----PGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P PG G+PG + P G PG P PG K K PGGLAG +G Sbjct: 2274 PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE-------- 2325 Query: 76 TFPGAL----VPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAVVP-QPGAGV 126 PGA +PG + A +A + G G G PG G G VP PG Sbjct: 2326 --PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPG 2383 Query: 127 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIPG--- 181 PG +GLPG LPGA PGV PG TG + PG G AG PG Sbjct: 2384 PPGVKGDLGLPG------LPGA--PGVVGFPG-QTGPRGEMGQPGPSGERGLAGPPGREG 2434 Query: 182 -VGPFGGPQPGVPLGYP----IKAPKLPGGYGLPYTTGKL-----------PYGYGPGGV 225 GP G P P +G P +K K G GLP G+ P GP G+ Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGL 2494 Query: 226 AGAAGKAGYPTGTG-----------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVG 268 G G G G +GP A + G G G Sbjct: 2495 TGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRG 2554 Query: 269 GAGVPGVPGA-----------IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPG- 315 G PG G+ +PG+ G+ G G P AA K G VPG Sbjct: 2555 DNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG-----VPGI 2609 Query: 316 ----------GPGFGPGVVGVPGA-GVPG-------VGVPGA----------GIPVVPG- 346 GP G GV GA G+ G G PG G P VPG Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669 Query: 347 AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-------- 398 +G PG G++ P+ + G + G G P G GGFPG Sbjct: 2670 SGAPGKE--GLIGPKGDRGFDGQPGPKGDQGEKGERGTP----GIGGFPGPSGNDGSAGP 2723 Query: 399 -----------------------------VGVGGIPGVAGVPGVGGVPGVGGVPG 424 VG G+PG G G G PG G G Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 139 bits (351), Expect = 7e-33 Identities = 222/765 (29%), Positives = 268/765 (35%), Gaps = 156/765 (20%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPAL----GPGGKPLKPVPG--GLAGAGLGAGLGAF 72 PS P GVPG+ PG G+ G +P L G G+P K G G G GL Sbjct: 373 PSGPPGVPGS-PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431 Query: 73 PA-------VTF----------PGAL-------VPGGVADAAAAYKAAKAGAGLGGVPGV 108 P + F PG L V G + G G+PG+ Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 109 GGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV------- 159 GL G Q AG+K PG GLPG +PG FPG PG+ Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG-FPG-------FPGAQGDPGLKGEKGET 543 Query: 160 --PTGAGVKPKAPGVGG--------AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGL 209 P G P PG+ G G PGV GP+ + L PG G Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Query: 210 PYTTGKL----PYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFG---- 257 P + G P GYGP G G G G P G GP+ + + G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 258 ------AGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 G G+ +G G PG+PG PGI GI G P G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 310 AGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVPG----------AGIPG-AAVPG 356 + G PG PG G+PGA G P V +PG G P PG G+PG +PG Sbjct: 724 GKM--GEPGL-PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPG 780 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFG--------VGVGGIPGV 407 E + G G G G GA G PG G G G Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 408 AGVPGV--GGVPGVGGVPGVGISPEAQAAAAAKAAK-YGLVPGVGVAPGVGVAPGVGVAP 464 G+PG+ G PG G PG+ P Q + Y PG+ PG G+ P Sbjct: 841 PGIPGLDRSGFPGETGSPGI---PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP 897 Query: 465 GVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLG-A 519 G PG PG PG +PGI G G A + +G Sbjct: 898 GAIGPPG---PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 G PGL G PG GVPG+ G+ G +PG A PG G LG+ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPGM---PGLKGLKGLPGP----------AGPPGPRGDLGS 1001 Query: 580 LGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL---------- 626 G G PG G+ G+ +K K G G AG GL G+ GL Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 627 -----GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G PG G G+ P K + G PG L P P GA Sbjct: 1060 EGTRPGPPGPTGDPGL-PGDMGKKGEMGQPGPPGH-LGPAGPEGA 1102 Score = 137 bits (346), Expect = 2e-32 Identities = 208/704 (29%), Positives = 250/704 (35%), Gaps = 104/704 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P+ P G PG P G PG G G P P P G AG G + P PG Sbjct: 609 PAGPAGPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGP-RGELSVSTPVPGPPGPPG 662 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYP 141 P G G G PG+ G LG +P P +PG +PG+G PG P Sbjct: 663 PPG-------------HPGPQGPPGIPGSLGKCGDPGLPGPDG--EPG-IPGIGFPG--P 704 Query: 142 GGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-- 197 G FPG G P G P PG+ GA G P V GG PG P G+P Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA-KGEPAVAMPGG--PGTP-GFPGE 760 Query: 198 ---------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 248 I P LPG G P G L G G G G+ G P GP+ A Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEG-LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVP-GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 K G G G G+PG+ PG G G+ P + G Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPG 877 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAK 365 L P G G++G PGA +G PG G P PG G PG +PGV Sbjct: 878 NPGILGPPGEDGVIGMMGFPGA----IGPPGPPGNPGTPGQRGSPG--IPGVKGQRGTPG 931 Query: 366 AAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG-----GIPGVAGVPGVGGVPGVG 420 A + G PG G G GF G G+PG+ G+ G+ G+PG Sbjct: 932 AKGEQGDKG-NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 421 GVPGVGISPEAQAAAAAKAAKYGL-----------VPGVGVAPGVGVAPGVGVAPGVGLA 469 G PG P + + GL +PG G PG PG+ Sbjct: 991 GPPG----PRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGL--- 1043 Query: 470 PGVGVAPGVGVAPGV--GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIP 522 PG+ G PG G PG GP G K Q LG G P Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP 1103 Query: 523 GLGVGVGVPG-------LGVGA-----GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G G+PG LG G PG+ G+PGF PG + + + + Sbjct: 1104 GSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM-GIRGDQGRDGI 1162 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA----AKAAQFGLVGAAGLGGLGVGGL 626 PG G G G + P G G A A + A + G +G AG G G Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIE 1221 Query: 627 GVPGVGGL-GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 669 G PG GL G I P G PG P PG +G Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265 Score = 133 bits (335), Expect = 5e-31 Identities = 205/666 (30%), Positives = 246/666 (36%), Gaps = 112/666 (16%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGG- 85 G+PGA P G+PG +P GP G P P G G FPGA+ P G Sbjct: 174 GLPGAPGPQGLPGPPGFP--GPVGPPGPP---GFFG--------------FPGAMGPRGP 214 Query: 86 ---VADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVY 140 + + +K + GL G PG G V P +K G +G PG Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGT-VIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 LPG + PG P G KP GV G F G GV G PG+ IK Sbjct: 274 GPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPG-FPGSEGVKGNRG-FPGLMGEDGIKG 330 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 259 K G G P G Y Y G G G P G GPQ + G Sbjct: 331 QK--GDIGPPGFRGPTEY-YDTYQEKGDEGTPGPPGPRGARGPQGPS------------G 375 Query: 260 AAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------VGTPAAAAAAAAAAKAAKYGA 308 GV PG G+ PG+ GA PG+ G G +GTP + A + G Sbjct: 376 PPGV-PGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 309 AAGLVPGGPGF------GPGVVGVPG----AGVPGV----GVPG---AGIPVVPGA-GIP 350 PG PG PG G+PG G+PGV G PG P +PG G+P Sbjct: 435 -----PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489 Query: 351 GA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----------- 398 G + GV AA G+ G+ G P + GA G PG Sbjct: 490 GLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP-GAQGDPGLKGEKGETLQPEG 548 Query: 399 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 VGV G PG+ G PG G+ G+ G PGV P + A K P PG + Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-----PGDPGS 603 Query: 458 PGVGVAPGVGLAPGVGV--APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 515 PG G PG G PG+ GV APG PG A + V+ Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPG--EAGPRGELSVSTPVPGPPGP 660 Query: 516 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVL 574 G PG G+PG G PGL G PG +PG K PG Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG---IPGIGFPGPPGPKGDQGFPGTK 717 Query: 575 GGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G +G PG G G A A G G G G G +G+PG+ Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSG-EHGEIGLPGLP 776 Query: 633 GLGGIP 638 GL G P Sbjct: 777 GLPGTP 782 Score = 131 bits (330), Expect = 2e-30 Identities = 218/776 (28%), Positives = 272/776 (35%), Gaps = 168/776 (21%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAI----PGGVPGGVFYPALGPGGKPLKPVPGGLAG 62 A PR G L + + P P G PG P G+PG +LG G P P P G G Sbjct: 642 AGPR-GELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG-----SLGKCGDPGLPGPDGEPG 695 Query: 63 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAGA 117 P + FPG PG D G G G+PG GL G Sbjct: 696 ---------IPGIGFPGP--PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744 Query: 118 VVPQPGAGVKPGKVPG----------VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 167 V PG PG PG +GLPG+ PG LPG PG L G P G +P Sbjct: 745 AVAMPGGPGTPG-FPGERGNSGEHGEIGLPGL-PG--LPGT--PGNEGLDG-PRGDPGQP 797 Query: 168 KAPGVGG----------AFAGIPGVGPFGGPQ-----------PGVP----LGYPIK--A 200 PG G G+PG+ G Q PG+P G+P + + Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGS 857 Query: 201 PKLPGGYGLPYTTGKLPYGYGPG--------------GVAGAAGKAGYPTGTGV------ 240 P +PG G G+ Y PG G GA G G P G Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS 917 Query: 241 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GT 290 G + A + K G + + +G G PG+ G PG G GV G Sbjct: 918 PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG-------VGVPG- 338 P A G L G PG+ G+PG+ G+PG +G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 339 AGIPVVPGA-------GIPGAAV---PGVVSPEAAAKAAAKAAKYG--ARPG----VGVG 382 AG P +PG G PG + PG P K G +PG +G Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPA 1097 Query: 383 GIPTYGVGAGGFPGF--------GVGVGGIPGVAGVPGVGGVPGVGGVPG----VGI-SP 429 G P G+ G PG +G GI G+ G PG+ G PG+ G PG +GI Sbjct: 1098 G-PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + + A + G + PG PG A G APG PG A +G A Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA--MGDAGP 1214 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 549 GP G+ G PGL G +PG G PG G P Sbjct: 1215 RGPTGIEGF--------------------PGPPGL-PGAIIPGQTGNRGPPGSRGSPGAP 1253 Query: 550 GFGAVPGA-LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 608 G PG+ + K K PG G G G +G PG + G Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Query: 609 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G+ G G G +G +G PG G G PP + + PG P PG Sbjct: 1314 FPGVKGEKGNPGF-LGSIGPPGPIGPKG-PPGVRGDPGTLKIISLPGSPGPPGTPG 1367 Score = 108 bits (269), Expect = 2e-23 Identities = 181/619 (29%), Positives = 216/619 (34%), Gaps = 130/619 (21%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYP-ALGPGGKPLKP----------VPGGLAGAGLGAG 68 +P PG G PG GV G + +P A+GP G P P +PG G Sbjct: 875 YPGNPGILGPPGE--DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 69 LGAFPAVTFPG----ALVPGGVADAA----AAYKAAKAGAGLGGVPGVGGL-GVSAGAVV 119 G PG + V G + A K G+ G+PG+ GL G+ A Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 120 PQP----GAGVKPGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 P P G+ PG+ PG+ G+PG +PG++ G G P AG +P PG+ G Sbjct: 993 PGPRGDLGSTGNPGE-PGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAG-RPGLPGIHG 1048 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKA 232 G G +PG P P P LPG G G+ P GP G GA G Sbjct: 1049 LQGDKGEPGYSEGTRPGPP--GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSP 1106 Query: 233 GYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GT 290 G P G GP G G+L G G PG+PG PG G G+ G Sbjct: 1107 GSPGLPGKPGPHGDLGFK---------GIKGLLGPPGIRGPPGLPG-FPGSPGPMGIRGD 1156 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG---------- 338 A + + G P GP PG G G G PG G+PG Sbjct: 1157 QGRDGIPGPAGEKGETGLLRA--PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 339 ---AGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 394 GI PG G+PGA +PG G+R G G P G Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPP---------GSRGSPGAPGPP-------GP 1258 Query: 395 PGFGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPG 453 PG V G+ G G G PG G PG G G PG APG Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP--------------------PGRLGAPG 1298 Query: 454 VGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 512 PG PG PGV G G +G IGP G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR------------- 1345 Query: 513 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYG- 567 G PG + +PG G PG G PG PG L K K G Sbjct: 1346 -------GDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGK 1398 Query: 568 AAVPGVLGGLGALGGVGIP 586 PG G G G G P Sbjct: 1399 PGTPGPAGEKGNKGSKGEP 1417 Score = 107 bits (268), Expect = 3e-23 Identities = 177/598 (29%), Positives = 218/598 (36%), Gaps = 105/598 (17%) Query: 135 GLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGVGPFGGPQPG 191 G PG PG PG + F G LPG P G P PG+ G+ GI G+ F G PG Sbjct: 52 GFPGP-PGS--PGQKGFTGPEGLPG-PQGPKGFPGLPGLTGSKGVRGISGLPGFSG-SPG 106 Query: 192 VPLGYPIKAPKLPGGYGLPYTTG----KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 247 +P P G YGL G K G+ G+ G G G P G+ Q A Sbjct: 107 LP-----GTPGNTGPYGLVGVPGCSGSKGEQGFP--GLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 A + G G+ G G+PG PG PG VG P +G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPG-FPG-----PVGPPGPPGF---------FG 204 Query: 308 AAAGLVPGGP--GFGPGVVGVPG-AGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAA 364 + P GP G V+G G GV G+ P G PG + + P+ Sbjct: 205 FPGAMGPRGPKGHMGERVIGHKGERGVKGLTGP---------PGPPGTVIVTLTGPDNRT 255 Query: 365 KAAAKAAKYGA--RPG-VGVGGIP--TYG--VGAGGFPGF-----GVGVGGIPGVAGVPG 412 + GA PG G G+P +YG GA G PG GV G PG GV G Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315 Query: 413 VGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGL-----VPGVGVAPGVGVAPGVGV 462 G PG+ G G+ I P Y PG G G Sbjct: 316 NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375 Query: 463 APGVGLAPGVGVAPGVGVAPG-VGVAPGIG----PGGVAAAAKSAAKVAAKAQLRAAAGL 517 PGV +PG PG+ APG G+ G PG A + A L + G Sbjct: 376 PPGVPGSPG-SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 518 GA---------------GIPGLGVGVGVPGLGVGAGVPGL-----GVGAGVPGFGAVPGA 557 G+PG G+PG+ G PGL G PG +PG Sbjct: 435 PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG- 493 Query: 558 LAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA--GPAAAAAAAKAAAKAAQFGLV 613 L K G+ G G+ G G+PG G GA P + Q G+ Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553 Query: 614 GAAGL----GGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G GL G G+ G+ G PGV GL G P A + + G PG SP PG A Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPG-PKGELALSGEKGDQGPPGDPGSPGSPGPA 610 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 139 bits (351), Expect = 7e-33 Identities = 222/765 (29%), Positives = 268/765 (35%), Gaps = 156/765 (20%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPAL----GPGGKPLKPVPG--GLAGAGLGAGLGAF 72 PS P GVPG+ PG G+ G +P L G G+P K G G G GL Sbjct: 373 PSGPPGVPGS-PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431 Query: 73 PA-------VTF----------PGAL-------VPGGVADAAAAYKAAKAGAGLGGVPGV 108 P + F PG L V G + G G+PG+ Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 109 GGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV------- 159 GL G Q AG+K PG GLPG +PG FPG PG+ Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG-FPG-------FPGAQGDPGLKGEKGET 543 Query: 160 --PTGAGVKPKAPGVGG--------AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGL 209 P G P PG+ G G PGV GP+ + L PG G Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Query: 210 PYTTGKL----PYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFG---- 257 P + G P GYGP G G G G P G GP+ + + G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 258 ------AGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 G G+ +G G PG+PG PGI GI G P G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 310 AGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVPG----------AGIPG-AAVPG 356 + G PG PG G+PGA G P V +PG G P PG G+PG +PG Sbjct: 724 GKM--GEPGL-PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPG 780 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFG--------VGVGGIPGV 407 E + G G G G GA G PG G G G Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 408 AGVPGV--GGVPGVGGVPGVGISPEAQAAAAAKAAK-YGLVPGVGVAPGVGVAPGVGVAP 464 G+PG+ G PG G PG+ P Q + Y PG+ PG G+ P Sbjct: 841 PGIPGLDRSGFPGETGSPGI---PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP 897 Query: 465 GVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLG-A 519 G PG PG PG +PGI G G A + +G Sbjct: 898 GAIGPPG---PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 G PGL G PG GVPG+ G+ G +PG A PG G LG+ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPGM---PGLKGLKGLPGP----------AGPPGPRGDLGS 1001 Query: 580 LGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL---------- 626 G G PG G+ G+ +K K G G AG GL G+ GL Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 627 -----GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G PG G G+ P K + G PG L P P GA Sbjct: 1060 EGTRPGPPGPTGDPGL-PGDMGKKGEMGQPGPPGH-LGPAGPEGA 1102 Score = 137 bits (346), Expect = 2e-32 Identities = 208/704 (29%), Positives = 250/704 (35%), Gaps = 104/704 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P+ P G PG P G PG G G P P P G AG G + P PG Sbjct: 609 PAGPAGPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGP-RGELSVSTPVPGPPGPPG 662 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYP 141 P G G G PG+ G LG +P P +PG +PG+G PG P Sbjct: 663 PPG-------------HPGPQGPPGIPGSLGKCGDPGLPGPDG--EPG-IPGIGFPG--P 704 Query: 142 GGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-- 197 G FPG G P G P PG+ GA G P V GG PG P G+P Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA-KGEPAVAMPGG--PGTP-GFPGE 760 Query: 198 ---------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 248 I P LPG G P G L G G G G+ G P GP+ A Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEG-LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVP-GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 K G G G G+PG+ PG G G+ P + G Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPG 877 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAK 365 L P G G++G PGA +G PG G P PG G PG +PGV Sbjct: 878 NPGILGPPGEDGVIGMMGFPGA----IGPPGPPGNPGTPGQRGSPG--IPGVKGQRGTPG 931 Query: 366 AAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG-----GIPGVAGVPGVGGVPGVG 420 A + G PG G G GF G G+PG+ G+ G+ G+PG Sbjct: 932 AKGEQGDKG-NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 421 GVPGVGISPEAQAAAAAKAAKYGL-----------VPGVGVAPGVGVAPGVGVAPGVGLA 469 G PG P + + GL +PG G PG PG+ Sbjct: 991 GPPG----PRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGL--- 1043 Query: 470 PGVGVAPGVGVAPGV--GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIP 522 PG+ G PG G PG GP G K Q LG G P Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP 1103 Query: 523 GLGVGVGVPG-------LGVGA-----GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G G+PG LG G PG+ G+PGF PG + + + + Sbjct: 1104 GSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM-GIRGDQGRDGI 1162 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA----AKAAQFGLVGAAGLGGLGVGGL 626 PG G G G + P G G A A + A + G +G AG G G Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIE 1221 Query: 627 GVPGVGGL-GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 669 G PG GL G I P G PG P PG +G Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265 Score = 133 bits (335), Expect = 5e-31 Identities = 205/666 (30%), Positives = 246/666 (36%), Gaps = 112/666 (16%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGG- 85 G+PGA P G+PG +P GP G P P G G FPGA+ P G Sbjct: 174 GLPGAPGPQGLPGPPGFP--GPVGPPGPP---GFFG--------------FPGAMGPRGP 214 Query: 86 ---VADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVY 140 + + +K + GL G PG G V P +K G +G PG Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGT-VIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 LPG + PG P G KP GV G F G GV G PG+ IK Sbjct: 274 GPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPG-FPGSEGVKGNRG-FPGLMGEDGIKG 330 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 259 K G G P G Y Y G G G P G GPQ + G Sbjct: 331 QK--GDIGPPGFRGPTEY-YDTYQEKGDEGTPGPPGPRGARGPQGPS------------G 375 Query: 260 AAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------VGTPAAAAAAAAAAKAAKYGA 308 GV PG G+ PG+ GA PG+ G G +GTP + A + G Sbjct: 376 PPGV-PGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 309 AAGLVPGGPGF------GPGVVGVPG----AGVPGV----GVPG---AGIPVVPGA-GIP 350 PG PG PG G+PG G+PGV G PG P +PG G+P Sbjct: 435 -----PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489 Query: 351 GA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----------- 398 G + GV AA G+ G+ G P + GA G PG Sbjct: 490 GLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP-GAQGDPGLKGEKGETLQPEG 548 Query: 399 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 VGV G PG+ G PG G+ G+ G PGV P + A K P PG + Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-----PGDPGS 603 Query: 458 PGVGVAPGVGLAPGVGV--APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 515 PG G PG G PG+ GV APG PG A + V+ Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPG--EAGPRGELSVSTPVPGPPGP 660 Query: 516 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVL 574 G PG G+PG G PGL G PG +PG K PG Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG---IPGIGFPGPPGPKGDQGFPGTK 717 Query: 575 GGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G +G PG G G A A G G G G G +G+PG+ Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSG-EHGEIGLPGLP 776 Query: 633 GLGGIP 638 GL G P Sbjct: 777 GLPGTP 782 Score = 131 bits (330), Expect = 2e-30 Identities = 218/776 (28%), Positives = 272/776 (35%), Gaps = 168/776 (21%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAI----PGGVPGGVFYPALGPGGKPLKPVPGGLAG 62 A PR G L + + P P G PG P G+PG +LG G P P P G G Sbjct: 642 AGPR-GELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG-----SLGKCGDPGLPGPDGEPG 695 Query: 63 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAGA 117 P + FPG PG D G G G+PG GL G Sbjct: 696 ---------IPGIGFPGP--PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744 Query: 118 VVPQPGAGVKPGKVPG----------VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 167 V PG PG PG +GLPG+ PG LPG PG L G P G +P Sbjct: 745 AVAMPGGPGTPG-FPGERGNSGEHGEIGLPGL-PG--LPGT--PGNEGLDG-PRGDPGQP 797 Query: 168 KAPGVGG----------AFAGIPGVGPFGGPQ-----------PGVP----LGYPIK--A 200 PG G G+PG+ G Q PG+P G+P + + Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGS 857 Query: 201 PKLPGGYGLPYTTGKLPYGYGPG--------------GVAGAAGKAGYPTGTGV------ 240 P +PG G G+ Y PG G GA G G P G Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS 917 Query: 241 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GT 290 G + A + K G + + +G G PG+ G PG G GV G Sbjct: 918 PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG-------VGVPG- 338 P A G L G PG+ G+PG+ G+PG +G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 339 AGIPVVPGA-------GIPGAAV---PGVVSPEAAAKAAAKAAKYG--ARPG----VGVG 382 AG P +PG G PG + PG P K G +PG +G Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPA 1097 Query: 383 GIPTYGVGAGGFPGF--------GVGVGGIPGVAGVPGVGGVPGVGGVPG----VGI-SP 429 G P G+ G PG +G GI G+ G PG+ G PG+ G PG +GI Sbjct: 1098 G-PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + + A + G + PG PG A G APG PG A +G A Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA--MGDAGP 1214 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 549 GP G+ G PGL G +PG G PG G P Sbjct: 1215 RGPTGIEGF--------------------PGPPGL-PGAIIPGQTGNRGPPGSRGSPGAP 1253 Query: 550 GFGAVPGA-LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 608 G PG+ + K K PG G G G +G PG + G Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Query: 609 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G+ G G G +G +G PG G G PP + + PG P PG Sbjct: 1314 FPGVKGEKGNPGF-LGSIGPPGPIGPKG-PPGVRGDPGTLKIISLPGSPGPPGTPG 1367 Score = 110 bits (276), Expect = 3e-24 Identities = 191/666 (28%), Positives = 228/666 (34%), Gaps = 163/666 (24%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYP-ALGPGGKPLKP----------VPGGLAGAGLGAG 68 +P PG G PG GV G + +P A+GP G P P +PG G Sbjct: 875 YPGNPGILGPPGE--DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 69 LGAFPAVTFPG----ALVPGGVADAA----AAYKAAKAGAGLGGVPGVGGL-GVSAGAVV 119 G PG + V G + A K G+ G+PG+ GL G+ A Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 120 PQP----GAGVKPGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 P P G+ PG+ PG+ G+PG +PG++ G G P AG +P PG+ G Sbjct: 993 PGPRGDLGSTGNPGE-PGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAG-RPGLPGIHG 1048 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKA 232 G G +PG P P P LPG G G+ P GP G GA G Sbjct: 1049 LQGDKGEPGYSEGTRPGPP--GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSP 1106 Query: 233 GYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GT 290 G P G GP G G+L G G PG+PG PG G G+ G Sbjct: 1107 GSPGLPGKPGPHGDLGFK---------GIKGLLGPPGIRGPPGLPG-FPGSPGPMGIRGD 1156 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG---------- 338 A + + G P GP PG G G G PG G+PG Sbjct: 1157 QGRDGIPGPAGEKGETGLLRA--PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 339 ---AGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 394 GI PG G+PGA +PG G+R G G P G Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPP---------GSRGSPGAPGPP-------GP 1258 Query: 395 PGFGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPG 453 PG V G+ G G G PG G PG G G PG APG Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP--------------------PGRLGAPG 1298 Query: 454 VGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 512 PG PG PGV G G +G IGP G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR------------- 1345 Query: 513 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 572 G PG + +PG G PG PG PG PG Sbjct: 1346 -------GDPGTLKIISLPGSPGPPGTPG------EPGMQGEPGP-------------PG 1379 Query: 573 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G G PG K + G G AG G G G PG Sbjct: 1380 PPGNLGPCGPRGKPG------------------KDGKPGTPGPAGEKG-NKGSKGEPGPA 1420 Query: 633 GLGGIP 638 G G+P Sbjct: 1421 GSDGLP 1426 Score = 107 bits (268), Expect = 3e-23 Identities = 177/598 (29%), Positives = 218/598 (36%), Gaps = 105/598 (17%) Query: 135 GLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGVGPFGGPQPG 191 G PG PG PG + F G LPG P G P PG+ G+ GI G+ F G PG Sbjct: 52 GFPGP-PGS--PGQKGFTGPEGLPG-PQGPKGFPGLPGLTGSKGVRGISGLPGFSG-SPG 106 Query: 192 VPLGYPIKAPKLPGGYGLPYTTG----KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 247 +P P G YGL G K G+ G+ G G G P G+ Q A Sbjct: 107 LP-----GTPGNTGPYGLVGVPGCSGSKGEQGFP--GLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 A + G G+ G G+PG PG PG VG P +G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPG-FPG-----PVGPPGPPGF---------FG 204 Query: 308 AAAGLVPGGP--GFGPGVVGVPG-AGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAA 364 + P GP G V+G G GV G+ P G PG + + P+ Sbjct: 205 FPGAMGPRGPKGHMGERVIGHKGERGVKGLTGP---------PGPPGTVIVTLTGPDNRT 255 Query: 365 KAAAKAAKYGA--RPG-VGVGGIP--TYG--VGAGGFPGF-----GVGVGGIPGVAGVPG 412 + GA PG G G+P +YG GA G PG GV G PG GV G Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315 Query: 413 VGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGL-----VPGVGVAPGVGVAPGVGV 462 G PG+ G G+ I P Y PG G G Sbjct: 316 NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375 Query: 463 APGVGLAPGVGVAPGVGVAPG-VGVAPGIG----PGGVAAAAKSAAKVAAKAQLRAAAGL 517 PGV +PG PG+ APG G+ G PG A + A L + G Sbjct: 376 PPGVPGSPG-SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 518 GA---------------GIPGLGVGVGVPGLGVGAGVPGL-----GVGAGVPGFGAVPGA 557 G+PG G+PG+ G PGL G PG +PG Sbjct: 435 PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG- 493 Query: 558 LAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA--GPAAAAAAAKAAAKAAQFGLV 613 L K G+ G G+ G G+PG G GA P + Q G+ Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553 Query: 614 GAAGL----GGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G GL G G+ G+ G PGV GL G P A + + G PG SP PG A Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPG-PKGELALSGEKGDQGPPGDPGSPGSPGPA 610 Score = 102 bits (253), Expect = 2e-21 Identities = 147/512 (28%), Positives = 183/512 (35%), Gaps = 86/512 (16%) Query: 23 PSRPG-----GVPGAIPGGVPG--GVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P PG G+PG P G PG G PG L+ +PG + G+ G + Sbjct: 975 PGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 135 FPG AG G+PG+ GL G P G +PG G Sbjct: 1033 GFPGR-------------------AGRPGLPGIHGLQGDKGE--PGYSEGTRPGPPGPTG 1071 Query: 136 LPGVYPGGVLP----GARFPGVGVLPGVPTGAGVKPKAPGVGG--------AFAGIPGV- 182 PG+ PG + G P + P P GA P +PG+ G F GI G+ Sbjct: 1072 DPGL-PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLL 1130 Query: 183 GPFG--GPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGT 238 GP G GP PG+P G+P PG G+ G+ +P GP G G G P G Sbjct: 1131 GPPGIRGP-PGLP-GFPGS----PGPMGIRGDQGRDGIP---GPAGEKGETGLLRAPPGP 1181 Query: 239 GVGPQAAAAAAAKAAAKFGA--GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 296 P A A + A F G G + G G G+ G PG G+ G P Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG-FPGPPGLPGAIIPGQTGN 1240 Query: 297 AAAAAKAAKYGAAAGLVPGGPGF-GPGVVGVPG----AGVPGV-GVPGAGIPVVPGAGIP 350 GA PG PG G V+G+ G G PG G PG + P + Sbjct: 1241 RGPPGSRGSPGA-----PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVG-VGGI-PTYGVGAGGFPGFGVGVG------ 402 PG+ P G + G +G I P +G G PG G Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355 Query: 403 -----GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 G PG G PG+ G PG G PG + P K K G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPG-NLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 458 PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 G A GL PG+ G +P G Sbjct: 1415 GEPGPAGSDGL-PGLKGKRGDSGSPATWTTRG 1445 Score = 93.6 bits (231), Expect = 5e-19 Identities = 150/505 (29%), Positives = 189/505 (37%), Gaps = 80/505 (15%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG--GVPGAIPG-GVPGGVFYPA-LGPGGKPLKPV 56 + GL A PG L S +P PG G+PG++ G+PG LG G+ +P Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 57 PGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPG-VGGLGVS 114 G+ G G + T PG PG D K G G G PG +G G Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGP--PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 115 AGAVVP-QPGAGVKPGKVPGVGLPGVY----PGGV-----LPGARFPG----VGVL---- 156 P PG KPG +G G+ P G+ LPG FPG +G+ Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG--FPGSPGPMGIRGDQG 1158 Query: 157 -PGVPTGAGVKPKA------------PGVGGA--------FAGIPG-VGPFGGPQPGVPL 194 G+P AG K + PG GA F G+PG G G P P Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218 Query: 195 G---YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG---VGPQAAAAA 248 G +P P LPG +P TG GP G G+ G G P G +G + + Sbjct: 1219 GIEGFP-GPPGLPGAI-IPGQTGNR----GPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS 1272 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYG 307 K G AG + G G PG PG +PG G G G P G Sbjct: 1273 MGHPGPKGPPGTAGDMGPPGRLGAPGTPG-LPGPRGDPGFQGFPGVKGEKGNPGFLGSIG 1331 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA----GIPVVPGA-GIPGA-AVPGVVSPE 361 + P GP PGV G PG + + +PG+ G P PG G PG PG + P Sbjct: 1332 PPGPIGPKGP---PGVRGDPGT-LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387 Query: 362 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 K K G G G G+ G PG G G+PG+ G G G P Sbjct: 1388 GPRGKPGKDGKPGTPGPAGEKG----NKGSKGEPG-PAGSDGLPGLKGKRGDSGSPATWT 1442 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVP 446 G + +Q A + G VP Sbjct: 1443 TRGFVFTRHSQTTAIPSCPE-GTVP 1466 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 139 bits (351), Expect = 7e-33 Identities = 222/765 (29%), Positives = 268/765 (35%), Gaps = 156/765 (20%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPAL----GPGGKPLKPVPG--GLAGAGLGAGLGAF 72 PS P GVPG+ PG G+ G +P L G G+P K G G G GL Sbjct: 373 PSGPPGVPGS-PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431 Query: 73 PA-------VTF----------PGAL-------VPGGVADAAAAYKAAKAGAGLGGVPGV 108 P + F PG L V G + G G+PG+ Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 109 GGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV------- 159 GL G Q AG+K PG GLPG +PG FPG PG+ Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG-FPG-------FPGAQGDPGLKGEKGET 543 Query: 160 --PTGAGVKPKAPGVGG--------AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGL 209 P G P PG+ G G PGV GP+ + L PG G Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Query: 210 PYTTGKL----PYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFG---- 257 P + G P GYGP G G G G P G GP+ + + G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 258 ------AGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 G G+ +G G PG+PG PGI GI G P G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 310 AGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVPG----------AGIPG-AAVPG 356 + G PG PG G+PGA G P V +PG G P PG G+PG +PG Sbjct: 724 GKM--GEPGL-PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPG 780 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFG--------VGVGGIPGV 407 E + G G G G GA G PG G G G Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 408 AGVPGV--GGVPGVGGVPGVGISPEAQAAAAAKAAK-YGLVPGVGVAPGVGVAPGVGVAP 464 G+PG+ G PG G PG+ P Q + Y PG+ PG G+ P Sbjct: 841 PGIPGLDRSGFPGETGSPGI---PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP 897 Query: 465 GVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLG-A 519 G PG PG PG +PGI G G A + +G Sbjct: 898 GAIGPPG---PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 G PGL G PG GVPG+ G+ G +PG A PG G LG+ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPGM---PGLKGLKGLPGP----------AGPPGPRGDLGS 1001 Query: 580 LGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL---------- 626 G G PG G+ G+ +K K G G AG GL G+ GL Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 627 -----GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G PG G G+ P K + G PG L P P GA Sbjct: 1060 EGTRPGPPGPTGDPGL-PGDMGKKGEMGQPGPPGH-LGPAGPEGA 1102 Score = 137 bits (346), Expect = 2e-32 Identities = 208/704 (29%), Positives = 250/704 (35%), Gaps = 104/704 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P+ P G PG P G PG G G P P P G AG G + P PG Sbjct: 609 PAGPAGPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGP-RGELSVSTPVPGPPGPPG 662 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYP 141 P G G G PG+ G LG +P P +PG +PG+G PG P Sbjct: 663 PPG-------------HPGPQGPPGIPGSLGKCGDPGLPGPDG--EPG-IPGIGFPG--P 704 Query: 142 GGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-- 197 G FPG G P G P PG+ GA G P V GG PG P G+P Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA-KGEPAVAMPGG--PGTP-GFPGE 760 Query: 198 ---------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 248 I P LPG G P G L G G G G+ G P GP+ A Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEG-LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVP-GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 K G G G G+PG+ PG G G+ P + G Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPG 877 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAK 365 L P G G++G PGA +G PG G P PG G PG +PGV Sbjct: 878 NPGILGPPGEDGVIGMMGFPGA----IGPPGPPGNPGTPGQRGSPG--IPGVKGQRGTPG 931 Query: 366 AAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG-----GIPGVAGVPGVGGVPGVG 420 A + G PG G G GF G G+PG+ G+ G+ G+PG Sbjct: 932 AKGEQGDKG-NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 421 GVPGVGISPEAQAAAAAKAAKYGL-----------VPGVGVAPGVGVAPGVGVAPGVGLA 469 G PG P + + GL +PG G PG PG+ Sbjct: 991 GPPG----PRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGL--- 1043 Query: 470 PGVGVAPGVGVAPGV--GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIP 522 PG+ G PG G PG GP G K Q LG G P Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP 1103 Query: 523 GLGVGVGVPG-------LGVGA-----GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G G+PG LG G PG+ G+PGF PG + + + + Sbjct: 1104 GSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM-GIRGDQGRDGI 1162 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA----AKAAQFGLVGAAGLGGLGVGGL 626 PG G G G + P G G A A + A + G +G AG G G Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIE 1221 Query: 627 GVPGVGGL-GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 669 G PG GL G I P G PG P PG +G Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265 Score = 133 bits (335), Expect = 5e-31 Identities = 205/666 (30%), Positives = 246/666 (36%), Gaps = 112/666 (16%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGG- 85 G+PGA P G+PG +P GP G P P G G FPGA+ P G Sbjct: 174 GLPGAPGPQGLPGPPGFP--GPVGPPGPP---GFFG--------------FPGAMGPRGP 214 Query: 86 ---VADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVY 140 + + +K + GL G PG G V P +K G +G PG Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGT-VIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 LPG + PG P G KP GV G F G GV G PG+ IK Sbjct: 274 GPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPG-FPGSEGVKGNRG-FPGLMGEDGIKG 330 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 259 K G G P G Y Y G G G P G GPQ + G Sbjct: 331 QK--GDIGPPGFRGPTEY-YDTYQEKGDEGTPGPPGPRGARGPQGPS------------G 375 Query: 260 AAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------VGTPAAAAAAAAAAKAAKYGA 308 GV PG G+ PG+ GA PG+ G G +GTP + A + G Sbjct: 376 PPGV-PGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 309 AAGLVPGGPGF------GPGVVGVPG----AGVPGV----GVPG---AGIPVVPGA-GIP 350 PG PG PG G+PG G+PGV G PG P +PG G+P Sbjct: 435 -----PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489 Query: 351 GA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----------- 398 G + GV AA G+ G+ G P + GA G PG Sbjct: 490 GLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP-GAQGDPGLKGEKGETLQPEG 548 Query: 399 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 VGV G PG+ G PG G+ G+ G PGV P + A K P PG + Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-----PGDPGS 603 Query: 458 PGVGVAPGVGLAPGVGV--APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 515 PG G PG G PG+ GV APG PG A + V+ Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPG--EAGPRGELSVSTPVPGPPGP 660 Query: 516 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVL 574 G PG G+PG G PGL G PG +PG K PG Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG---IPGIGFPGPPGPKGDQGFPGTK 717 Query: 575 GGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G +G PG G G A A G G G G G +G+PG+ Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSG-EHGEIGLPGLP 776 Query: 633 GLGGIP 638 GL G P Sbjct: 777 GLPGTP 782 Score = 131 bits (330), Expect = 2e-30 Identities = 218/776 (28%), Positives = 272/776 (35%), Gaps = 168/776 (21%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAI----PGGVPGGVFYPALGPGGKPLKPVPGGLAG 62 A PR G L + + P P G PG P G+PG +LG G P P P G G Sbjct: 642 AGPR-GELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG-----SLGKCGDPGLPGPDGEPG 695 Query: 63 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAGA 117 P + FPG PG D G G G+PG GL G Sbjct: 696 ---------IPGIGFPGP--PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744 Query: 118 VVPQPGAGVKPGKVPG----------VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 167 V PG PG PG +GLPG+ PG LPG PG L G P G +P Sbjct: 745 AVAMPGGPGTPG-FPGERGNSGEHGEIGLPGL-PG--LPGT--PGNEGLDG-PRGDPGQP 797 Query: 168 KAPGVGG----------AFAGIPGVGPFGGPQ-----------PGVP----LGYPIK--A 200 PG G G+PG+ G Q PG+P G+P + + Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGS 857 Query: 201 PKLPGGYGLPYTTGKLPYGYGPG--------------GVAGAAGKAGYPTGTGV------ 240 P +PG G G+ Y PG G GA G G P G Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS 917 Query: 241 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GT 290 G + A + K G + + +G G PG+ G PG G GV G Sbjct: 918 PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG-------VGVPG- 338 P A G L G PG+ G+PG+ G+PG +G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 339 AGIPVVPGA-------GIPGAAV---PGVVSPEAAAKAAAKAAKYG--ARPG----VGVG 382 AG P +PG G PG + PG P K G +PG +G Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPA 1097 Query: 383 GIPTYGVGAGGFPGF--------GVGVGGIPGVAGVPGVGGVPGVGGVPG----VGI-SP 429 G P G+ G PG +G GI G+ G PG+ G PG+ G PG +GI Sbjct: 1098 G-PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + + A + G + PG PG A G APG PG A +G A Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA--MGDAGP 1214 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 549 GP G+ G PGL G +PG G PG G P Sbjct: 1215 RGPTGIEGF--------------------PGPPGL-PGAIIPGQTGNRGPPGSRGSPGAP 1253 Query: 550 GFGAVPGA-LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 608 G PG+ + K K PG G G G +G PG + G Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Query: 609 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G+ G G G +G +G PG G G PP + + PG P PG Sbjct: 1314 FPGVKGEKGNPGF-LGSIGPPGPIGPKG-PPGVRGDPGTLKIISLPGSPGPPGTPG 1367 Score = 110 bits (276), Expect = 3e-24 Identities = 191/666 (28%), Positives = 228/666 (34%), Gaps = 163/666 (24%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYP-ALGPGGKPLKP----------VPGGLAGAGLGAG 68 +P PG G PG GV G + +P A+GP G P P +PG G Sbjct: 875 YPGNPGILGPPGE--DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 69 LGAFPAVTFPG----ALVPGGVADAA----AAYKAAKAGAGLGGVPGVGGL-GVSAGAVV 119 G PG + V G + A K G+ G+PG+ GL G+ A Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 120 PQP----GAGVKPGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 P P G+ PG+ PG+ G+PG +PG++ G G P AG +P PG+ G Sbjct: 993 PGPRGDLGSTGNPGE-PGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAG-RPGLPGIHG 1048 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKA 232 G G +PG P P P LPG G G+ P GP G GA G Sbjct: 1049 LQGDKGEPGYSEGTRPGPP--GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSP 1106 Query: 233 GYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GT 290 G P G GP G G+L G G PG+PG PG G G+ G Sbjct: 1107 GSPGLPGKPGPHGDLGFK---------GIKGLLGPPGIRGPPGLPG-FPGSPGPMGIRGD 1156 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG---------- 338 A + + G P GP PG G G G PG G+PG Sbjct: 1157 QGRDGIPGPAGEKGETGLLRA--PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 339 ---AGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 394 GI PG G+PGA +PG G+R G G P G Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPP---------GSRGSPGAPGPP-------GP 1258 Query: 395 PGFGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPG 453 PG V G+ G G G PG G PG G G PG APG Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP--------------------PGRLGAPG 1298 Query: 454 VGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 512 PG PG PGV G G +G IGP G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR------------- 1345 Query: 513 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 572 G PG + +PG G PG PG PG PG Sbjct: 1346 -------GDPGTLKIISLPGSPGPPGTPG------EPGMQGEPGP-------------PG 1379 Query: 573 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G G PG K + G G AG G G G PG Sbjct: 1380 PPGNLGPCGPRGKPG------------------KDGKPGTPGPAGEKG-NKGSKGEPGPA 1420 Query: 633 GLGGIP 638 G G+P Sbjct: 1421 GSDGLP 1426 Score = 107 bits (268), Expect = 3e-23 Identities = 177/598 (29%), Positives = 218/598 (36%), Gaps = 105/598 (17%) Query: 135 GLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGVGPFGGPQPG 191 G PG PG PG + F G LPG P G P PG+ G+ GI G+ F G PG Sbjct: 52 GFPGP-PGS--PGQKGFTGPEGLPG-PQGPKGFPGLPGLTGSKGVRGISGLPGFSG-SPG 106 Query: 192 VPLGYPIKAPKLPGGYGLPYTTG----KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 247 +P P G YGL G K G+ G+ G G G P G+ Q A Sbjct: 107 LP-----GTPGNTGPYGLVGVPGCSGSKGEQGFP--GLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 A + G G+ G G+PG PG PG VG P +G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPG-FPG-----PVGPPGPPGF---------FG 204 Query: 308 AAAGLVPGGP--GFGPGVVGVPG-AGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAA 364 + P GP G V+G G GV G+ P G PG + + P+ Sbjct: 205 FPGAMGPRGPKGHMGERVIGHKGERGVKGLTGP---------PGPPGTVIVTLTGPDNRT 255 Query: 365 KAAAKAAKYGA--RPG-VGVGGIP--TYG--VGAGGFPGF-----GVGVGGIPGVAGVPG 412 + GA PG G G+P +YG GA G PG GV G PG GV G Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315 Query: 413 VGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGL-----VPGVGVAPGVGVAPGVGV 462 G PG+ G G+ I P Y PG G G Sbjct: 316 NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375 Query: 463 APGVGLAPGVGVAPGVGVAPG-VGVAPGIG----PGGVAAAAKSAAKVAAKAQLRAAAGL 517 PGV +PG PG+ APG G+ G PG A + A L + G Sbjct: 376 PPGVPGSPG-SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 518 GA---------------GIPGLGVGVGVPGLGVGAGVPGL-----GVGAGVPGFGAVPGA 557 G+PG G+PG+ G PGL G PG +PG Sbjct: 435 PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG- 493 Query: 558 LAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA--GPAAAAAAAKAAAKAAQFGLV 613 L K G+ G G+ G G+PG G GA P + Q G+ Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553 Query: 614 GAAGL----GGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G GL G G+ G+ G PGV GL G P A + + G PG SP PG A Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPG-PKGELALSGEKGDQGPPGDPGSPGSPGPA 610 Score = 102 bits (253), Expect = 2e-21 Identities = 147/512 (28%), Positives = 183/512 (35%), Gaps = 86/512 (16%) Query: 23 PSRPG-----GVPGAIPGGVPG--GVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P PG G+PG P G PG G PG L+ +PG + G+ G + Sbjct: 975 PGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 135 FPG AG G+PG+ GL G P G +PG G Sbjct: 1033 GFPGR-------------------AGRPGLPGIHGLQGDKGE--PGYSEGTRPGPPGPTG 1071 Query: 136 LPGVYPGGVLP----GARFPGVGVLPGVPTGAGVKPKAPGVGG--------AFAGIPGV- 182 PG+ PG + G P + P P GA P +PG+ G F GI G+ Sbjct: 1072 DPGL-PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLL 1130 Query: 183 GPFG--GPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGT 238 GP G GP PG+P G+P PG G+ G+ +P GP G G G P G Sbjct: 1131 GPPGIRGP-PGLP-GFPGS----PGPMGIRGDQGRDGIP---GPAGEKGETGLLRAPPGP 1181 Query: 239 GVGPQAAAAAAAKAAAKFGA--GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 296 P A A + A F G G + G G G+ G PG G+ G P Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG-FPGPPGLPGAIIPGQTGN 1240 Query: 297 AAAAAKAAKYGAAAGLVPGGPGF-GPGVVGVPG----AGVPGV-GVPGAGIPVVPGAGIP 350 GA PG PG G V+G+ G G PG G PG + P + Sbjct: 1241 RGPPGSRGSPGA-----PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVG-VGGI-PTYGVGAGGFPGFGVGVG------ 402 PG+ P G + G +G I P +G G PG G Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355 Query: 403 -----GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 G PG G PG+ G PG G PG + P K K G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPG-NLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 458 PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 G A GL PG+ G +P G Sbjct: 1415 GEPGPAGSDGL-PGLKGKRGDSGSPATWTTRG 1445 Score = 93.6 bits (231), Expect = 5e-19 Identities = 150/505 (29%), Positives = 189/505 (37%), Gaps = 80/505 (15%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG--GVPGAIPG-GVPGGVFYPA-LGPGGKPLKPV 56 + GL A PG L S +P PG G+PG++ G+PG LG G+ +P Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 57 PGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPG-VGGLGVS 114 G+ G G + T PG PG D K G G G PG +G G Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGP--PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 115 AGAVVP-QPGAGVKPGKVPGVGLPGVY----PGGV-----LPGARFPG----VGVL---- 156 P PG KPG +G G+ P G+ LPG FPG +G+ Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG--FPGSPGPMGIRGDQG 1158 Query: 157 -PGVPTGAGVKPKA------------PGVGGA--------FAGIPG-VGPFGGPQPGVPL 194 G+P AG K + PG GA F G+PG G G P P Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218 Query: 195 G---YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG---VGPQAAAAA 248 G +P P LPG +P TG GP G G+ G G P G +G + + Sbjct: 1219 GIEGFP-GPPGLPGAI-IPGQTGNR----GPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS 1272 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYG 307 K G AG + G G PG PG +PG G G G P G Sbjct: 1273 MGHPGPKGPPGTAGDMGPPGRLGAPGTPG-LPGPRGDPGFQGFPGVKGEKGNPGFLGSIG 1331 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA----GIPVVPGA-GIPGA-AVPGVVSPE 361 + P GP PGV G PG + + +PG+ G P PG G PG PG + P Sbjct: 1332 PPGPIGPKGP---PGVRGDPGT-LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387 Query: 362 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 K K G G G G+ G PG G G+PG+ G G G P Sbjct: 1388 GPRGKPGKDGKPGTPGPAGEKG----NKGSKGEPG-PAGSDGLPGLKGKRGDSGSPATWT 1442 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVP 446 G + +Q A + G VP Sbjct: 1443 TRGFVFTRHSQTTAIPSCPE-GTVP 1466 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 139 bits (351), Expect = 7e-33 Identities = 222/765 (29%), Positives = 268/765 (35%), Gaps = 156/765 (20%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPAL----GPGGKPLKPVPG--GLAGAGLGAGLGAF 72 PS P GVPG+ PG G+ G +P L G G+P K G G G GL Sbjct: 373 PSGPPGVPGS-PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431 Query: 73 PA-------VTF----------PGAL-------VPGGVADAAAAYKAAKAGAGLGGVPGV 108 P + F PG L V G + G G+PG+ Sbjct: 432 PGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGL 491 Query: 109 GGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV------- 159 GL G Q AG+K PG GLPG +PG FPG PG+ Sbjct: 492 PGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPG-FPG-------FPGAQGDPGLKGEKGET 543 Query: 160 --PTGAGVKPKAPGVGG--------AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGL 209 P G P PG+ G G PGV GP+ + L PG G Sbjct: 544 LQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS 603 Query: 210 PYTTGKL----PYGYGPGGVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFG---- 257 P + G P GYGP G G G G P G GP+ + + G Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663 Query: 258 ------AGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 309 G G+ +G G PG+PG PGI GI G P G Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCP 723 Query: 310 AGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVPG----------AGIPG-AAVPG 356 + G PG PG G+PGA G P V +PG G P PG G+PG +PG Sbjct: 724 GKM--GEPGL-PGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPG 780 Query: 357 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFG--------VGVGGIPGV 407 E + G G G G GA G PG G G G Sbjct: 781 TPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 408 AGVPGV--GGVPGVGGVPGVGISPEAQAAAAAKAAK-YGLVPGVGVAPGVGVAPGVGVAP 464 G+PG+ G PG G PG+ P Q + Y PG+ PG G+ P Sbjct: 841 PGIPGLDRSGFPGETGSPGI---PGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP 897 Query: 465 GVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLG-A 519 G PG PG PG +PGI G G A + +G Sbjct: 898 GAIGPPG---PPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDK 954 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 G PGL G PG GVPG+ G+ G +PG A PG G LG+ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPGM---PGLKGLKGLPGP----------AGPPGPRGDLGS 1001 Query: 580 LGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL---------- 626 G G PG G+ G+ +K K G G AG GL G+ GL Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059 Query: 627 -----GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G PG G G+ P K + G PG L P P GA Sbjct: 1060 EGTRPGPPGPTGDPGL-PGDMGKKGEMGQPGPPGH-LGPAGPEGA 1102 Score = 137 bits (346), Expect = 2e-32 Identities = 208/704 (29%), Positives = 250/704 (35%), Gaps = 104/704 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV 82 P+ P G PG P G PG G G P P P G AG G + P PG Sbjct: 609 PAGPAGPPGYGPQGEPG-----LQGTQGVPGAPGPPGEAGP-RGELSVSTPVPGPPGPPG 662 Query: 83 PGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYP 141 P G G G PG+ G LG +P P +PG +PG+G PG P Sbjct: 663 PPG-------------HPGPQGPPGIPGSLGKCGDPGLPGPDG--EPG-IPGIGFPG--P 704 Query: 142 GGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-- 197 G FPG G P G P PG+ GA G P V GG PG P G+P Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGA-KGEPAVAMPGG--PGTP-GFPGE 760 Query: 198 ---------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAA 248 I P LPG G P G L G G G G+ G P GP+ A Sbjct: 761 RGNSGEHGEIGLPGLPGLPGTPGNEG-LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVP-GAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 K G G G G+PG+ PG G G+ P + G Sbjct: 820 PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGI--PGHQGEMGPLGQRGYPG 877 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAK 365 L P G G++G PGA +G PG G P PG G PG +PGV Sbjct: 878 NPGILGPPGEDGVIGMMGFPGA----IGPPGPPGNPGTPGQRGSPG--IPGVKGQRGTPG 931 Query: 366 AAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG-----GIPGVAGVPGVGGVPGVG 420 A + G PG G G GF G G+PG+ G+ G+ G+PG Sbjct: 932 AKGEQGDKG-NPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 421 GVPGVGISPEAQAAAAAKAAKYGL-----------VPGVGVAPGVGVAPGVGVAPGVGLA 469 G PG P + + GL +PG G PG PG+ Sbjct: 991 GPPG----PRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGL--- 1043 Query: 470 PGVGVAPGVGVAPGV--GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIP 522 PG+ G PG G PG GP G K Q LG G P Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAP 1103 Query: 523 GLGVGVGVPG-------LGVGA-----GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 570 G G+PG LG G PG+ G+PGF PG + + + + Sbjct: 1104 GSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPM-GIRGDQGRDGI 1162 Query: 571 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA----AKAAQFGLVGAAGLGGLGVGGL 626 PG G G G + P G G A A + A + G +G AG G G Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRG-PTGIE 1221 Query: 627 GVPGVGGL-GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLG 669 G PG GL G I P G PG P PG +G Sbjct: 1222 GFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIG 1265 Score = 133 bits (335), Expect = 5e-31 Identities = 205/666 (30%), Positives = 246/666 (36%), Gaps = 112/666 (16%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGG- 85 G+PGA P G+PG +P GP G P P G G FPGA+ P G Sbjct: 174 GLPGAPGPQGLPGPPGFP--GPVGPPGPP---GFFG--------------FPGAMGPRGP 214 Query: 86 ---VADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVY 140 + + +K + GL G PG G V P +K G +G PG Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGT-VIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273 Query: 141 PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKA 200 LPG + PG P G KP GV G F G GV G PG+ IK Sbjct: 274 GPSGLPGESYGSEKGAPGDP-GLQGKPGKDGVPG-FPGSEGVKGNRG-FPGLMGEDGIKG 330 Query: 201 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 259 K G G P G Y Y G G G P G GPQ + G Sbjct: 331 QK--GDIGPPGFRGPTEY-YDTYQEKGDEGTPGPPGPRGARGPQGPS------------G 375 Query: 260 AAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------VGTPAAAAAAAAAAKAAKYGA 308 GV PG G+ PG+ GA PG+ G G +GTP + A + G Sbjct: 376 PPGV-PGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 309 AAGLVPGGPGF------GPGVVGVPG----AGVPGV----GVPG---AGIPVVPGA-GIP 350 PG PG PG G+PG G+PGV G PG P +PG G+P Sbjct: 435 -----PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLP 489 Query: 351 GA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----------- 398 G + GV AA G+ G+ G P + GA G PG Sbjct: 490 GLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFP-GAQGDPGLKGEKGETLQPEG 548 Query: 399 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 VGV G PG+ G PG G+ G+ G PGV P + A K P PG + Sbjct: 549 QVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP-----PGDPGS 603 Query: 458 PGVGVAPGVGLAPGVGV--APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAA 515 PG G PG G PG+ GV APG PG A + V+ Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPG--EAGPRGELSVSTPVPGPPGP 660 Query: 516 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVL 574 G PG G+PG G PGL G PG +PG K PG Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPG---IPGIGFPGPPGPKGDQGFPGTK 717 Query: 575 GGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G +G PG G G A A G G G G G +G+PG+ Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSG-EHGEIGLPGLP 776 Query: 633 GLGGIP 638 GL G P Sbjct: 777 GLPGTP 782 Score = 131 bits (330), Expect = 2e-30 Identities = 218/776 (28%), Positives = 272/776 (35%), Gaps = 168/776 (21%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAI----PGGVPGGVFYPALGPGGKPLKPVPGGLAG 62 A PR G L + + P P G PG P G+PG +LG G P P P G G Sbjct: 642 AGPR-GELSVSTPVPGPPGPPGPPGHPGPQGPPGIPG-----SLGKCGDPGLPGPDGEPG 695 Query: 63 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAGA 117 P + FPG PG D G G G+PG GL G Sbjct: 696 ---------IPGIGFPGP--PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744 Query: 118 VVPQPGAGVKPGKVPG----------VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 167 V PG PG PG +GLPG+ PG LPG PG L G P G +P Sbjct: 745 AVAMPGGPGTPG-FPGERGNSGEHGEIGLPGL-PG--LPGT--PGNEGLDG-PRGDPGQP 797 Query: 168 KAPGVGG----------AFAGIPGVGPFGGPQ-----------PGVP----LGYPIK--A 200 PG G G+PG+ G Q PG+P G+P + + Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGS 857 Query: 201 PKLPGGYGLPYTTGKLPYGYGPG--------------GVAGAAGKAGYPTGTGV------ 240 P +PG G G+ Y PG G GA G G P G Sbjct: 858 PGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGS 917 Query: 241 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GT 290 G + A + K G + + +G G PG+ G PG G GV G Sbjct: 918 PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG-------VGVPG- 338 P A G L G PG+ G+PG+ G+PG +G PG Sbjct: 978 PGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037 Query: 339 AGIPVVPGA-------GIPGAAV---PGVVSPEAAAKAAAKAAKYG--ARPG----VGVG 382 AG P +PG G PG + PG P K G +PG +G Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPA 1097 Query: 383 GIPTYGVGAGGFPGF--------GVGVGGIPGVAGVPGVGGVPGVGGVPG----VGI-SP 429 G P G+ G PG +G GI G+ G PG+ G PG+ G PG +GI Sbjct: 1098 G-PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156 Query: 430 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + + A + G + PG PG A G APG PG A +G A Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA--MGDAGP 1214 Query: 490 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 549 GP G+ G PGL G +PG G PG G P Sbjct: 1215 RGPTGIEGF--------------------PGPPGL-PGAIIPGQTGNRGPPGSRGSPGAP 1253 Query: 550 GFGAVPGA-LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 608 G PG+ + K K PG G G G +G PG + G Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Query: 609 QFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G+ G G G +G +G PG G G PP + + PG P PG Sbjct: 1314 FPGVKGEKGNPGF-LGSIGPPGPIGPKG-PPGVRGDPGTLKIISLPGSPGPPGTPG 1367 Score = 110 bits (276), Expect = 3e-24 Identities = 191/666 (28%), Positives = 228/666 (34%), Gaps = 163/666 (24%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYP-ALGPGGKPLKP----------VPGGLAGAGLGAG 68 +P PG G PG GV G + +P A+GP G P P +PG G Sbjct: 875 YPGNPGILGPPGE--DGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGA 932 Query: 69 LGAFPAVTFPG----ALVPGGVADAA----AAYKAAKAGAGLGGVPGVGGL-GVSAGAVV 119 G PG + V G + A K G+ G+PG+ GL G+ A Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 120 PQP----GAGVKPGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 174 P P G+ PG+ PG+ G+PG +PG++ G G P AG +P PG+ G Sbjct: 993 PGPRGDLGSTGNPGE-PGLRGIPGSMGNMGMPGSK--GKRGTLGFPGRAG-RPGLPGIHG 1048 Query: 175 AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKA 232 G G +PG P P P LPG G G+ P GP G GA G Sbjct: 1049 LQGDKGEPGYSEGTRPGPP--GPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSP 1106 Query: 233 GYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GT 290 G P G GP G G+L G G PG+PG PG G G+ G Sbjct: 1107 GSPGLPGKPGPHGDLGFK---------GIKGLLGPPGIRGPPGLPG-FPGSPGPMGIRGD 1156 Query: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG---------- 338 A + + G P GP PG G G G PG G+PG Sbjct: 1157 QGRDGIPGPAGEKGETGLLRA--PPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 339 ---AGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 394 GI PG G+PGA +PG G+R G G P G Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPP---------GSRGSPGAPGPP-------GP 1258 Query: 395 PGFGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPG 453 PG V G+ G G G PG G PG G G PG APG Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP--------------------PGRLGAPG 1298 Query: 454 VGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 512 PG PG PGV G G +G IGP G Sbjct: 1299 TPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR------------- 1345 Query: 513 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 572 G PG + +PG G PG PG PG PG Sbjct: 1346 -------GDPGTLKIISLPGSPGPPGTPG------EPGMQGEPGP-------------PG 1379 Query: 573 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 632 G LG G G PG K + G G AG G G G PG Sbjct: 1380 PPGNLGPCGPRGKPG------------------KDGKPGTPGPAGEKG-NKGSKGEPGPA 1420 Query: 633 GLGGIP 638 G G+P Sbjct: 1421 GSDGLP 1426 Score = 107 bits (268), Expect = 3e-23 Identities = 177/598 (29%), Positives = 218/598 (36%), Gaps = 105/598 (17%) Query: 135 GLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGVGPFGGPQPG 191 G PG PG PG + F G LPG P G P PG+ G+ GI G+ F G PG Sbjct: 52 GFPGP-PGS--PGQKGFTGPEGLPG-PQGPKGFPGLPGLTGSKGVRGISGLPGFSG-SPG 106 Query: 192 VPLGYPIKAPKLPGGYGLPYTTG----KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 247 +P P G YGL G K G+ G+ G G G P G+ Q A Sbjct: 107 LP-----GTPGNTGPYGLVGVPGCSGSKGEQGFP--GLPGTLGYPGIPGAAGLKGQKGAP 159 Query: 248 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 307 A + G G+ G G+PG PG PG VG P +G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPG-FPG-----PVGPPGPPGF---------FG 204 Query: 308 AAAGLVPGGP--GFGPGVVGVPG-AGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAA 364 + P GP G V+G G GV G+ P G PG + + P+ Sbjct: 205 FPGAMGPRGPKGHMGERVIGHKGERGVKGLTGP---------PGPPGTVIVTLTGPDNRT 255 Query: 365 KAAAKAAKYGA--RPG-VGVGGIP--TYG--VGAGGFPGF-----GVGVGGIPGVAGVPG 412 + GA PG G G+P +YG GA G PG GV G PG GV G Sbjct: 256 DLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKG 315 Query: 413 VGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGL-----VPGVGVAPGVGVAPGVGV 462 G PG+ G G+ I P Y PG G G Sbjct: 316 NRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSG 375 Query: 463 APGVGLAPGVGVAPGVGVAPG-VGVAPGIG----PGGVAAAAKSAAKVAAKAQLRAAAGL 517 PGV +PG PG+ APG G+ G PG A + A L + G Sbjct: 376 PPGVPGSPG-SSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGP 434 Query: 518 GA---------------GIPGLGVGVGVPGLGVGAGVPGL-----GVGAGVPGFGAVPGA 557 G+PG G+PG+ G PGL G PG +PG Sbjct: 435 PGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG- 493 Query: 558 LAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA--GPAAAAAAAKAAAKAAQFGLV 613 L K G+ G G+ G G+PG G GA P + Q G+ Sbjct: 494 LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553 Query: 614 GAAGL----GGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGA 666 G GL G G+ G+ G PGV GL G P A + + G PG SP PG A Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPG-PKGELALSGEKGDQGPPGDPGSPGSPGPA 610 Score = 102 bits (253), Expect = 2e-21 Identities = 147/512 (28%), Positives = 183/512 (35%), Gaps = 86/512 (16%) Query: 23 PSRPG-----GVPGAIPGGVPG--GVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 75 P PG G+PG P G PG G PG L+ +PG + G+ G + Sbjct: 975 PGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 135 FPG AG G+PG+ GL G P G +PG G Sbjct: 1033 GFPGR-------------------AGRPGLPGIHGLQGDKGE--PGYSEGTRPGPPGPTG 1071 Query: 136 LPGVYPGGVLP----GARFPGVGVLPGVPTGAGVKPKAPGVGG--------AFAGIPGV- 182 PG+ PG + G P + P P GA P +PG+ G F GI G+ Sbjct: 1072 DPGL-PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLL 1130 Query: 183 GPFG--GPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGT 238 GP G GP PG+P G+P PG G+ G+ +P GP G G G P G Sbjct: 1131 GPPGIRGP-PGLP-GFPGS----PGPMGIRGDQGRDGIP---GPAGEKGETGLLRAPPGP 1181 Query: 239 GVGPQAAAAAAAKAAAKFGA--GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 296 P A A + A F G G + G G G+ G PG G+ G P Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG-FPGPPGLPGAIIPGQTGN 1240 Query: 297 AAAAAKAAKYGAAAGLVPGGPGF-GPGVVGVPG----AGVPGV-GVPGAGIPVVPGAGIP 350 GA PG PG G V+G+ G G PG G PG + P + Sbjct: 1241 RGPPGSRGSPGA-----PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295 Query: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVG-VGGI-PTYGVGAGGFPGFGVGVG------ 402 PG+ P G + G +G I P +G G PG G Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355 Query: 403 -----GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 457 G PG G PG+ G PG G PG + P K K G G G Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPG-NLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 458 PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 G A GL PG+ G +P G Sbjct: 1415 GEPGPAGSDGL-PGLKGKRGDSGSPATWTTRG 1445 Score = 93.6 bits (231), Expect = 5e-19 Identities = 150/505 (29%), Positives = 189/505 (37%), Gaps = 80/505 (15%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG--GVPGAIPG-GVPGGVFYPA-LGPGGKPLKPV 56 + GL A PG L S +P PG G+PG++ G+PG LG G+ +P Sbjct: 983 LKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPG 1042 Query: 57 PGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPG-VGGLGVS 114 G+ G G + T PG PG D K G G G PG +G G Sbjct: 1043 LPGIHGLQGDKGEPGYSEGTRPGP--PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPE 1100 Query: 115 AGAVVP-QPGAGVKPGKVPGVGLPGVY----PGGV-----LPGARFPG----VGVL---- 156 P PG KPG +G G+ P G+ LPG FPG +G+ Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG--FPGSPGPMGIRGDQG 1158 Query: 157 -PGVPTGAGVKPKA------------PGVGGA--------FAGIPG-VGPFGGPQPGVPL 194 G+P AG K + PG GA F G+PG G G P P Sbjct: 1159 RDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPT 1218 Query: 195 G---YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG---VGPQAAAAA 248 G +P P LPG +P TG GP G G+ G G P G +G + + Sbjct: 1219 GIEGFP-GPPGLPGAI-IPGQTGNR----GPPGSRGSPGAPGPPGPPGSHVIGIKGDKGS 1272 Query: 249 AAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYG 307 K G AG + G G PG PG +PG G G G P G Sbjct: 1273 MGHPGPKGPPGTAGDMGPPGRLGAPGTPG-LPGPRGDPGFQGFPGVKGEKGNPGFLGSIG 1331 Query: 308 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA----GIPVVPGA-GIPGA-AVPGVVSPE 361 + P GP PGV G PG + + +PG+ G P PG G PG PG + P Sbjct: 1332 PPGPIGPKGP---PGVRGDPGT-LKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPC 1387 Query: 362 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 421 K K G G G G+ G PG G G+PG+ G G G P Sbjct: 1388 GPRGKPGKDGKPGTPGPAGEKG----NKGSKGEPG-PAGSDGLPGLKGKRGDSGSPATWT 1442 Query: 422 VPGVGISPEAQAAAAAKAAKYGLVP 446 G + +Q A + G VP Sbjct: 1443 TRGFVFTRHSQTTAIPSCPE-GTVP 1466 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 139 bits (350), Expect = 9e-33 Identities = 219/714 (30%), Positives = 257/714 (35%), Gaps = 126/714 (17%) Query: 23 PSRPGGVPGAI-PGGVPGGVFYPALGPGGKPLKPVPG--GLAGA-GLGAGLGAFPAVTFP 78 P P G+PG P GVPG L+ VPG GL G GL A LG+ P Sbjct: 905 PQGPPGIPGPPGPPGVPG-------------LQGVPGNNGLPGQPGLTAELGSLPIEQHL 951 Query: 79 GALVPGGVADAAAA---YKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVK------ 127 + G A Y K G G+PGV GL A + +P A Sbjct: 952 LKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSE 1011 Query: 128 --PGKVPGVGLPGVYPGGVLPGARF----PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 181 PG V GLPG PG LPG R PG+ PG P G PG GA G PG Sbjct: 1012 GDPGCVGSPGLPGP-PG--LPGQRGEEGPPGMRGSPGPPGPIG----PPGFPGA-VGSPG 1063 Query: 182 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTG 239 + G + L P PG G P TG LP G G G+AG+ G P G Sbjct: 1064 LPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPG 1123 Query: 240 V----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAA 295 GP A + + +G G G G PG PG PG G VG+P Sbjct: 1124 SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP-PGFPG--KVGSPGPPG 1180 Query: 296 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----GVPGAGIPVVPGAGIP 350 A G + +PG PG PG G+ G AG+ G+ G PG G P Sbjct: 1181 PQAEKGSEGIRGPSG--LPGSPG-PPGPPGIQGPAGLDGLDGKDGKPGL-------RGDP 1230 Query: 351 G-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIP 405 G A PG++ P G + G G P T GA G PG G G P Sbjct: 1231 GPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPP 1290 Query: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 465 G G PG G PG G+ VG+ + A G+ PG PG PG Sbjct: 1291 GHVGPPGPPGQPGPAGISAVGLKGDRGATGER---------GLAGLPGQPGPPGHPGPPG 1341 Query: 466 VGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGL 524 PG A G PG G GP G AA + K RA G G G Sbjct: 1342 ---EPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKG--RAGMPGGPGKSGS 1396 Query: 525 GVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--------------------AAKAA 564 VG PG G PG +G PG VPG++ + A Sbjct: 1397 MGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMA 1456 Query: 565 KYG---------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGA 615 Y AA PG G G G G PG P + + + Q GL G Sbjct: 1457 YYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-----APGSPGLPGQIGREGRQ-GLPGV 1510 Query: 616 AGLGGL----GVGGLGVPGVGGLGGIP-PAAAAKAAKYGVAARPGFGLSPIFPG 664 GL G G G+G+ G GL G P P K G G P PG Sbjct: 1511 RGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPG 1564 Score = 129 bits (324), Expect = 9e-30 Identities = 218/761 (28%), Positives = 257/761 (33%), Gaps = 141/761 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPAL-GPGGKPLKPVPGGLAG------AGLGAGLGAFPAV 75 P PGG PG P G G P GPGGKP KP G G L G F V Sbjct: 466 PGDPGGPPG--PKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF--V 521 Query: 76 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG----VSAGAVVPQPGAGVKPGKV 131 PG P G + G+ G G L V A +V GA G Sbjct: 522 GLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS- 580 Query: 132 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV--------- 182 PG GLPG+ +PG + P G+ P PG G AGI G Sbjct: 581 PGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGS---PGPPGPVGP-AGIKGAKGEPCEPCP 636 Query: 183 ----------------GPFGGP-QPGVP-LGYPIKAPKL--------------PGGYGLP 210 GP G +PG P G P K K PG G P Sbjct: 637 ALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTP 696 Query: 211 YTTGKLPYGYGPGGVAGAAGKAGYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGV 267 TTG+ P G GV G AG G G P A G G GV Sbjct: 697 GTTGR-PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGV 755 Query: 268 GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 327 G G PG PG +PG+ G G+ G PG PG PG+ G+P Sbjct: 756 GRPGKPGQPG-LPGVQGPPGLKGVQGEPGPPGRGVQGPQGE-----PGAPGL-PGIQGLP 808 Query: 328 GA-GVPG-VGVPGA-GIPVVPGA----GIPGAAV---PGVVSPEAAAKAAAKAAKYGARP 377 G G PG G GA G P V GA G PGA+V PG + + G R Sbjct: 809 GPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRG 868 Query: 378 GVGVGG---IPTYG----VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP- 429 G G P+ G G G PG +G PG G PG+ G PG GVPG+ P Sbjct: 869 EKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPG 928 Query: 430 -EAQAAAAAKAAKYGLVP---------------GVGVAPGVGVAPGVGVAPGVGLAPGVG 473 A+ G +P G PG V G G+ PG+ Sbjct: 929 NNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLD 988 Query: 474 VA-----------------------PGVGVAPGVGVAPGI-------GPGGVAAAAKSAA 503 PG +PG+ PG+ GP G+ + Sbjct: 989 NCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPG 1048 Query: 504 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 563 + A G G+PGL G+ GL G PG G PG PG L K Sbjct: 1049 PIGPPG-FPGAVG-SPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPG-LPGIKG 1105 Query: 564 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV 623 + G G G G G+PG AGP + + G G G G Sbjct: 1106 ERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG-PP 1164 Query: 624 GGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 664 G G PG G G PP A+ G+ G SP PG Sbjct: 1165 GPPGFPGKVGSPG-PPGPQAEKGSEGIRGPSGLPGSPGPPG 1204 Score = 115 bits (289), Expect = 1e-25 Identities = 195/686 (28%), Positives = 231/686 (33%), Gaps = 125/686 (18%) Query: 30 PGAIPGGVPGGVFYPALGP-GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVAD 88 P + G V GP GGK + +PG G G P A P A+ Sbjct: 317 PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDA--PLQCAE 374 Query: 89 AAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGA 148 K G G+PG G G + G+K G+PG Sbjct: 375 GPKGEKGESGALGPSGLPGSTG---EKGQKGEKGDGGIK-------GVPGK--------- 415 Query: 149 RFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYG 208 PG PG G PK F G G+ GP PG+P P G G Sbjct: 416 --PGRDGRPGEICVIG--PKGQKGDPGFVGPEGLAGEPGP-PGLPG---------PPGIG 461 Query: 209 LPYTTGKLPYG-------YGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAA 261 LP T G P G G G+ G G G P GV + G Sbjct: 462 LPGTPGD-PGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNF 520 Query: 262 GVLPG-VGGAGVPGVP---GAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGG 316 LPG G G PG P PGI GI G G P + ++ A+ A G Sbjct: 521 VGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGS 580 Query: 317 PGFGPGVVGVPG-AGVPGV-------------GVPGAGIPVVPGAGIPGAAVPGVVSPEA 362 PGF G+ G+PG AGVPG+ G PG PV P AGI GA A Sbjct: 581 PGF--GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP-AGIKGAKGEPCEPCPA 637 Query: 363 AAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV----------GVGGIPGVAGVPG 412 + + A PG P+ G G PGFG+ G+ G G AG PG Sbjct: 638 LSNLQDGDVRVVALPG------PSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPG 691 Query: 413 VGGVPGVGGVPGVGISPEAQAAAAAKAAK----------YGLVPGVGVAPGVGVAPGVGV 462 G PG G PG+ P Q A K K G V + PG G Sbjct: 692 DPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQG 751 Query: 463 APGVGL--APGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 519 GVG PG PGV PG+ GV GP G Sbjct: 752 PEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGE---------------P 796 Query: 520 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 579 G PGL G+ GL G PG G G V G A GA+V G G G Sbjct: 797 GAPGL---PGIQGLPGPRGPPGPTGEKGAQGSPGVKG--ATGPVGPPGASVSGPPGRDGQ 851 Query: 580 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV--GAAGLGGLGVGGLGVPGVGGLGGI 637 G G+ G GP + +Q L+ G G GL +G PG G GI Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911 Query: 638 P--------PAAAAKAAKYGVAARPG 655 P P G+ +PG Sbjct: 912 PGPPGPPGVPGLQGVPGNNGLPGQPG 937 Score = 104 bits (260), Expect = 2e-22 Identities = 163/538 (30%), Positives = 198/538 (36%), Gaps = 91/538 (16%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAVTFPGALVPG 84 G PG I P G PG V P L PG + + + G G G G +P T P L PG Sbjct: 1045 GPPGPIGPPGFPGAVGSPGL-PGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGL-PG 1102 Query: 85 GVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAVVPQPGAGVK------------- 127 + A + G G G+PG G G PQ +G K Sbjct: 1103 IKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPG 1162 Query: 128 -------PGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFA-- 177 PGKV G PG G R P G+ PG P G++ A G+ G Sbjct: 1163 PPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPA-GLDGLDGKD 1221 Query: 178 GIPGV----GPFGGPQPGVPLGYPIKA--------------PKLPGGYGLPYTTGKLPYG 219 G PG+ GP G P P G+ K P PG G P G+ P Sbjct: 1222 GKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGE-PGA 1280 Query: 220 YGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKA--AAKFGAGAAGVLPGVGGAGVPGVP 276 GP G G G G P G GP +A K A G AG+ G G PG P Sbjct: 1281 MGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPP 1340 Query: 277 GAIPGIGGIAG----------VGTPAAAAAAAAAAKAAKYG--AAAGLVPGGPGFGP--G 322 G PG G AG G P AA + + G AG+ PGGPG G Sbjct: 1341 GE-PGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGM-PGGPGKSGSMG 1398 Query: 323 VVGVPG-AGVPG-VGVPG-AGIPVVPGAGIPGAA--------VPGVVSPEAAAKAAAKAA 371 VG PG AG G G PG +G P +PG +PG+ + + E + A Sbjct: 1399 PVGPPGPAGERGHPGAPGPSGSPGLPG--VPGSMGDMVNYDEIKRFIRQEIIKMFDERMA 1456 Query: 372 KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 431 Y +R P A G PG G G PG G PG G+PG G G P Sbjct: 1457 YYTSRMQ-----FPMEMAAAPGRPG-PPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGV 1510 Query: 432 QAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 489 + K K + G+ G+ PG PG G G G+ PG+ PG Sbjct: 1511 RGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGI-PGIPGPPG 1567 Score = 93.6 bits (231), Expect = 5e-19 Identities = 138/445 (31%), Positives = 173/445 (38%), Gaps = 77/445 (17%) Query: 23 PSRPGGVPGAIPG-GVPG--------GVFYPALGPGGKPLKPVPGGLAG-AGLGA--GLG 70 P P G PG + G PG G+ P+ G G P P P G+ G AGL G Sbjct: 1163 PPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPS-GLPGSPGPPGPPGIQGPAGLDGLDGKD 1221 Query: 71 AFPAVTF-PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 129 P + PG P G+ +K GL G G G G+ +PGA +PG Sbjct: 1222 GKPGLRGDPGPAGPPGLM-GPPGFKGKTGHPGLPGPKGDCGKPGPPGST-GRPGAEGEPG 1279 Query: 130 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--------AFAGIPG 181 + G PG PG V P PG PG P AG+ A G+ G AG+PG Sbjct: 1280 AMGPQGRPGP-PGHVGP----PGP---PGQPGPAGIS--AVGLKGDRGATGERGLAGLPG 1329 Query: 182 V-GPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYP 235 GP G P P G A P G YG P G P G G AG G+AG P Sbjct: 1330 QPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD-PGAAGQKGQAGEKGRAGMP 1388 Query: 236 TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAA 294 G G A + G A PG G+ G+PGVPG++ + + Sbjct: 1389 GGPGKSGSMGPVGPPGPAGERGHPGA---PGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQ 1445 Query: 295 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVPGA----- 347 + Y + P PG G PG G PG PGA G P +PG Sbjct: 1446 EIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR--PGAPGSPGLPGQIGREG 1503 Query: 348 --GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV----GAGGFPGFG-V 399 G+PG +PG G + +G+G G+ G G PG+G + Sbjct: 1504 RQGLPGVRGLPGTK---------------GEKGDIGIGIAGENGLPGPPGPQGPPGYGKM 1548 Query: 400 GVGGIPGVAGVPGVGGVPGVGGVPG 424 G G G G+PG+ G PG G PG Sbjct: 1549 GATGPMGQQGIPGIPGPPGPMGQPG 1573 Score = 44.7 bits (104), Expect = 3e-04 Identities = 61/200 (30%), Positives = 74/200 (37%), Gaps = 30/200 (15%) Query: 466 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 V LAP G G G G+ PG G A +++ A L+ A G G G Sbjct: 328 VTLAPS-GPKGGKGER-GLPGPPG-SKGEKGARGNDCVRISPDAPLQCAEG-PKGEKGES 383 Query: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 +G GL G G G G VPG K + G PG + +G G G Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPG-----KPGRDGR--PGEICVIGPKGQKGD 436 Query: 586 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIPPAAAAK 644 PG V GP GL G G GL G G+G+PG G G PP Sbjct: 437 PGFV---GPE---------------GLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGD 478 Query: 645 AAKYGVAARPGFGLSPIFPG 664 G+ + G G P PG Sbjct: 479 KGSSGIPGKEGPGGKPGKPG 498 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 138 bits (348), Expect = 1e-32 Identities = 201/702 (28%), Positives = 254/702 (36%), Gaps = 117/702 (16%) Query: 23 PSRPGGVPG--------AIPG-----GVPG--GVFYPALGPGGKPLKPVPGGLAGAGLGA 67 P P G+PG IPG G+PG G P PG P +PVPG GL Sbjct: 499 PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558 Query: 68 -----------GLGAFPAVT-FPGAL-VPGGVAD-AAAAYKAAKAGAGLGGVPGVGGLGV 113 GL P + PG +PG + + Y + AG G PG G Sbjct: 559 LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKG--- 615 Query: 114 SAGAVVPQPGAGVKPGKVPGVGLPGV-----------YPGGVLPGARFP-GVGVLPGVPT 161 A + PG + G G+PG+ +PG G R P G+ PG+ Sbjct: 616 -AQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF--GDRGPAGLDGSPGLVG 672 Query: 162 GAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 221 G G P PG+ G+ + +GP G P P+G L G GLP G G Sbjct: 673 GTG-PPGFPGLRGSVGPVGPIGPAGIPG---PMG-------LSGNKGLPGIKG----DKG 717 Query: 222 PGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--A 278 G AG G+ GYP G VG K+ G G+ G G G PG Sbjct: 718 EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777 Query: 279 IPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AG 330 IPG G G G P + GA L P G G G PG G Sbjct: 778 IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837 Query: 331 VPG-VGVPG--AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386 + G VG G I G+PG + G + + + G + +G G P Sbjct: 838 LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897 Query: 387 Y--GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKY 442 +G G PG VG G PG G G G G G+ G GI + + K + Sbjct: 898 VPGPIGPLGLPGH-VGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956 Query: 443 GLVPGVG--VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVA 496 GL+ G G PG+ PG G+ PG+ G PG GP G Sbjct: 957 GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016 Query: 497 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 556 + + AK + A +G G G PGL G PG G G VPG Sbjct: 1017 GESGLQGEPGAKGDVGTAGSVG--------GTGEPGLRGEPGAPGEEGLQGKDGLKGVPG 1068 Query: 557 --ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG----------------AGPAA 596 L K +PG++G LG G G+PG G+VG GP Sbjct: 1069 GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTG 1128 Query: 597 AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 638 + K + G GA G G VG LG+ G G GIP Sbjct: 1129 EVGSRGPPGKIGKSGPKGARGTRG-AVGHLGLMGPDGEPGIP 1169 Score = 108 bits (269), Expect = 2e-23 Identities = 218/801 (27%), Positives = 271/801 (33%), Gaps = 178/801 (22%) Query: 22 HPSRPGGVPG--AIPG--GVPGGVFYPA----LGPGGKP-LKPVPGGLAGAGLGAGLGAF 72 HP PG +PG IPG G G YP GP G P K G + G LG Sbjct: 574 HPGLPG-LPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE 632 Query: 73 PAVTFPGAL----------VPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSAGAVVPQ 121 PG PG D A G G G PG GL S G V P Sbjct: 633 GERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPI 692 Query: 122 PGAGVKPGKVP---GVGLPGVY-------PGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 171 AG+ PG + GLPG+ G L +PG G+P G++ K+ Sbjct: 693 GPAGI-PGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP 751 Query: 172 VGGAFAGIPGV-GPFGGPQP-------GVPLGYPIKAPK-------LPGGYGLPYTTGKL 216 G G PG+ GP G P P G+P + PK PG GL T G+ Sbjct: 752 SGQT--GDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEE 809 Query: 217 -PYG----YGPGGVAGAAGKAGYPTGTG-------------------VGPQAAAAAAAKA 252 P G GP G G G AG P G VG Sbjct: 810 GPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869 Query: 253 AAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAG 311 K G+ G L G GV G PG PG+ G G +G P A G Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGP-PGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928 Query: 312 LVPGGPGFGPGVVGVPGA-------------------------GVPGV-GVPGA----GI 341 P G G+ G G G PG+ G+PG+ G+ Sbjct: 929 RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988 Query: 342 PVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 396 P PG G+ G P G+ P + + GA+ VG G VG G PG Sbjct: 989 PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG----SVGGTGEPG 1044 Query: 397 F----------GV----GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 442 G+ G+ G+PG G+PG G G G+PG+ I P ++ Sbjct: 1045 LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGI-IGPLGRSGQTGLPGPE 1103 Query: 443 GLV--PGVGVAPG-------VGVAPGVGVA--PG-VGLAPGVGVAPGVGVAPGVGVA--- 487 G+V PG PG +G VG PG +G + G G +G+ Sbjct: 1104 GIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPD 1163 Query: 488 --PGI----------------GPGGVAAAAKSAAKVAAKAQLRAAAG-LG-------AGI 521 PGI GP G + V R G +G G Sbjct: 1164 GEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGA 1223 Query: 522 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA-----KAAKYGAAVPGVLGG 576 G VGVPGL G G G G + G + K A + PG+ G Sbjct: 1224 EGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283 Query: 577 LGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 636 G LG GI G G + K G+ G G GL G G PGV G G Sbjct: 1284 QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLA-GAPGPPGVKGSSG 1342 Query: 637 IP--PAAAAKAAKYGVAARPG 655 +P P + G+ +PG Sbjct: 1343 LPGSPGIQGPKGEQGLPGQPG 1363 Score = 97.1 bits (240), Expect = 5e-20 Identities = 187/676 (27%), Positives = 234/676 (34%), Gaps = 140/676 (20%) Query: 28 GVPGAI-PGGVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGV 86 G PG + P G G + YP GP G VPG + GL +GA PG+ P G Sbjct: 876 GSPGPLGPQGEKGVMGYP--GPPG-----VPGPIGPLGLPGHVGARGP---PGSQGPKGQ 925 Query: 87 ADAAA--------AYKAAKAGAGLGGVPGVGGLGVSAG-----AVVPQPGAGVKPGKVPG 133 + + AK G G G GL G +PG PG Sbjct: 926 RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGD 985 Query: 134 VGLPGVYPG--GVLPGARFPGVGVLPGVP-----TGAGVKPKAPGVGGAFAGIPGVGPFG 186 GLPG PG G+ PG + G P +G +P A G G + G G G Sbjct: 986 RGLPGE-PGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPG 1044 Query: 187 -GPQPGVPLGYPIKAPK----LPGGYGLPYTTGKL----------PYGY-------GPGG 224 +PG P ++ +PGG GLP G+ P G GP G Sbjct: 1045 LRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEG 1104 Query: 225 VAGAAGKAGYPTGTG----------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 274 + G G+ G P G VG + K+ K G G + +G G G Sbjct: 1105 IVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDG 1164 Query: 275 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG 333 PG IPG G G P+ K + L P GP PG VG G G PG Sbjct: 1165 EPG-IPGYRGHQGQPGPSGLPGPKGE-KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPG 1222 Query: 334 V-GVPG-AGIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 386 G G G+P + GA G PG G + + K GA G GIP Sbjct: 1223 AEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPG 1282 Query: 387 YG--VGAGGFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 442 +G G G+ G+ G PG G PG G+PG+ G PG Sbjct: 1283 LQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPG------------------ 1324 Query: 443 GLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 502 G+ APG PGV + G+ +PG+ G PG PG Sbjct: 1325 --------RTGLAGAPG---PPGVKGSSGLPGSPGIQGPKGEQGLPG-QPG--------- 1363 Query: 503 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 562 + K R A G G PGL G PG G+ GF PG K Sbjct: 1364 --IQGKRGHRGAQGDQG-------PCGDPGL---KGQPGEYGVQGLTGFQGFPG----PK 1407 Query: 563 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG 622 + A + G+ G G +G G GP + G G G G Sbjct: 1408 GPEGDAGIVGISGPKGPIGHRG------NTGPLGREGIIGPTGRTGPRGEKGFRGETG-P 1460 Query: 623 VGGLGVPGVGGLGGIP 638 G G PG G G P Sbjct: 1461 QGPRGQPGPPGPPGAP 1476 Score = 76.6 bits (187), Expect = 7e-14 Identities = 123/477 (25%), Positives = 170/477 (35%), Gaps = 77/477 (16%) Query: 215 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 274 ++ Y GP G G G G P G GP G G+ G G+PG Sbjct: 483 EMEYLRGPKGDTGPPGPPG-PAGIP-GPSGKR------------GPRGIPGPHGNPGLPG 528 Query: 275 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG 333 +PG G P + + G + + P G G+ G PG G+PG Sbjct: 529 LPGP------KGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPG 582 Query: 334 -VGVPG----AGIPVVPG-------------------AGIPGAA----------VPGVVS 359 G+PG G P PG G PG A +PG+ Sbjct: 583 EQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRG 642 Query: 360 PEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIPGVAGVPGVGG 415 + +G R G+ G P G G GFPG VG G G AG+PG G Sbjct: 643 KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702 Query: 416 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 475 + G G+PG+ + + A + + G PG A G+ PG+ G G Sbjct: 703 LSGNKGLPGIK-GDKGEQGTAGELGEPG-YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGL 760 Query: 476 PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGV 535 G PG P PG + ++ + K L G PGL G G Sbjct: 761 QGPSGPPG----PEGFPGDIGIPGQNGPE-GPKGLLGNRG--PPGPPGLKGTQGEEGPIG 813 Query: 536 GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA- 592 G G G G+ PG + K G +G +G G VG+PG G+ G+ Sbjct: 814 AFGELGPRGKPGQKGYAGEPG----PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869 Query: 593 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAK 647 G + + G++G G G+ +G LG+PG G G P + K + Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQR 926 Score = 73.2 bits (178), Expect = 8e-13 Identities = 127/427 (29%), Positives = 158/427 (37%), Gaps = 53/427 (12%) Query: 26 PGGVPGAIPG--GVPGGVFYPA-LGPGGKP-LKPVPGGLAGAGLGAGLGAFPAVTFPGAL 81 P G+ G IPG G PG +GP G+ + PG + +G G AV G + Sbjct: 1102 PEGIVG-IPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLM 1160 Query: 82 VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAG---AVVPQPGAGVKPGKVPGVGLPG 138 P G Y+ + G G+PG G G V+ PG +PG V G G Sbjct: 1161 GPDG-EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERG 1219 Query: 139 VYPGGVLPGAR-FPGVGVLPGV--PTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLG 195 PGA + G +PG+ TG P PG G G+ G G + Sbjct: 1220 E------PGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE-QGLKGERGSEGNKGKKGAP 1272 Query: 196 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 255 P P +PG GL G Y +G G++G GK G P G Q Sbjct: 1273 GPSGKPGIPGLQGLLGPKGIQGY-HGADGISGNPGKIGPP-----GKQGLPGIRGGPGRT 1326 Query: 256 FGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV 313 AGA G PGV G +G+PG PG I G G G+ G P K G Sbjct: 1327 GLAGAPGP-PGVKGSSGLPGSPG-IQGPKGEQGLPGQPGIQG---------KRGHRGAQG 1375 Query: 314 PGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGAGIP--GAAVPGVVSPEAAAKAAAKA 370 GP PG+ G PG GV G+ G PG P A + G+ P+ Sbjct: 1376 DQGPCGDPGLKGQPGEYGVQGL----TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431 Query: 371 AKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPE 430 G +G PT G G GF G G G G G PG G PG + Sbjct: 1432 GPLGREGIIG----PTGRTGPRGEKGFR----GETGPQGPRGQPGPPGPPGAPGPRKQMD 1483 Query: 431 AQAAAAA 437 AA A Sbjct: 1484 INAAIQA 1490 Score = 67.0 bits (162), Expect = 5e-11 Identities = 81/278 (29%), Positives = 99/278 (35%), Gaps = 25/278 (8%) Query: 395 PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK--YGLVPGVGV-- 450 P G G PG AG+PG G G G+PG +P K K G PG V Sbjct: 490 PKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPG 549 Query: 451 ------APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK 504 G+ PG+ G+ PG+ PG P G A IG G A Sbjct: 550 EKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIP--GFAGNIGSPGYPGRQGLAGP 607 Query: 505 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 564 A +G+ PG +G G G+PG+ G G PG A Sbjct: 608 EGNPGPKGAQGFIGS--PGEAGQLGPEG---ERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662 Query: 565 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV 623 + PG++GG G G G+ G V GP A + GL G G G G Sbjct: 663 GLDGS-PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGT 721 Query: 624 GG-LGVPGVGGLGGI-----PPAAAAKAAKYGVAARPG 655 G LG PG G G PP K+ G PG Sbjct: 722 AGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG 759 Score = 55.8 bits (133), Expect = 1e-07 Identities = 90/327 (27%), Positives = 112/327 (34%), Gaps = 59/327 (18%) Query: 19 SILHPSRPGGVPGAIPG----GVPGGVFYPALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 74 ++L P P G PG + G PG Y G G P GL GA G P Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYK--GHVGVP------GLRGATGQQGPPGEPG 1249 Query: 75 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKV- 131 L ++ K A +G G+PG+ GL G G+ PGK+ Sbjct: 1250 DQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIG 1309 Query: 132 -PGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP- 188 PG GLPG+ G PG TG P PGV G+ +G+PG GP Sbjct: 1310 PPGKQGLPGIRGG---PGR------------TGLAGAPGPPGVKGS-SGLPGSPGIQGPK 1353 Query: 189 -QPGVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPGGVAGAAGKAGYPTGTGVGPQAA 245 + G+P G P GK + G G G G G P GV Q Sbjct: 1354 GEQGLP--------------GQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGV--QGL 1397 Query: 246 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 305 K G AG++ G+ G G I G +G + Sbjct: 1398 TGFQGFPGPKGPEGDAGIV------GISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE 1451 Query: 306 YGAAAGLVPGGPGFGPGVVGVPGAGVP 332 G P GP PG G PGA P Sbjct: 1452 KGFRGETGPQGPRGQPGPPGPPGAPGP 1478 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.144 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,856,911 Number of Sequences: 37866 Number of extensions: 2919824 Number of successful extensions: 57450 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 504 Number of HSP's successfully gapped in prelim test: 971 Number of HSP's that attempted gapping in prelim test: 13416 Number of HSP's gapped (non-prelim): 12517 length of query: 677 length of database: 18,247,518 effective HSP length: 109 effective length of query: 568 effective length of database: 14,120,124 effective search space: 8020230432 effective search space used: 8020230432 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.