BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126352608 elastin isoform e precursor [Homo sapiens] (705 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126352608 elastin isoform e precursor [Homo sapiens] 1412 0.0 gi|126352440 elastin isoform a precursor [Homo sapiens] 1401 0.0 gi|126352322 elastin isoform c precursor [Homo sapiens] 1359 0.0 gi|126352446 elastin isoform d precursor [Homo sapiens] 1347 0.0 gi|126352700 elastin isoform b precursor [Homo sapiens] 1337 0.0 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 189 8e-48 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 181 3e-45 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 176 7e-44 gi|48762934 alpha 2 type I collagen [Homo sapiens] 173 4e-43 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 173 4e-43 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 172 7e-43 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 172 1e-42 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 172 1e-42 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 172 1e-42 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 170 5e-42 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 158 2e-38 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 157 4e-38 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 157 4e-38 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 154 4e-37 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 151 2e-36 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 151 2e-36 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 146 6e-35 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 145 1e-34 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 144 4e-34 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 144 4e-34 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 143 5e-34 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 142 1e-33 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 142 1e-33 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 140 5e-33 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 140 5e-33 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 1412 bits (3656), Expect = 0.0 Identities = 705/705 (100%), Positives = 705/705 (100%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 480 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 480 Query: 481 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 540 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV Sbjct: 481 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 540 Query: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 600 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV Sbjct: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 600 Query: 601 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA 660 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA Sbjct: 601 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA 660 Query: 661 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 1401 bits (3626), Expect = 0.0 Identities = 705/724 (97%), Positives = 705/724 (97%), Gaps = 19/724 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVPGVGVA 461 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVPGVGVA Sbjct: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVA 480 Query: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 521 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL Sbjct: 481 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 540 Query: 522 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 581 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP Sbjct: 541 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 600 Query: 582 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 641 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV Sbjct: 601 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 660 Query: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 701 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG Sbjct: 661 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 720 Query: 702 RKRK 705 RKRK Sbjct: 721 RKRK 724 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 1359 bits (3517), Expect = 0.0 Identities = 687/710 (96%), Positives = 687/710 (96%), Gaps = 23/710 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 475 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 Query: 476 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG Sbjct: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 Query: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI Sbjct: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 Query: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 655 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA Sbjct: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 Query: 656 AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 AKY GVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 AKY------------------GVAARPGFGLSPIFPGGACLGKACGRKRK 692 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 1347 bits (3487), Expect = 0.0 Identities = 687/729 (94%), Positives = 687/729 (94%), Gaps = 42/729 (5%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 456 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 Query: 457 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 516 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 Query: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 636 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 Query: 637 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 696 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 661 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 702 Query: 697 GKACGRKRK 705 GKACGRKRK Sbjct: 703 GKACGRKRK 711 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 1337 bits (3460), Expect = 0.0 Identities = 677/705 (96%), Positives = 677/705 (96%), Gaps = 28/705 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 180 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP Sbjct: 111 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 170 Query: 181 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 240 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG Sbjct: 171 GVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 230 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT Sbjct: 231 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 290 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 360 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP Sbjct: 291 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIP 350 Query: 361 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 420 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV Sbjct: 351 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 410 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 480 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP Sbjct: 411 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 470 Query: 481 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 540 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV Sbjct: 471 GVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGV 530 Query: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 600 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV Sbjct: 531 PGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVV 590 Query: 601 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGA 660 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY Sbjct: 591 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKY-- 648 Query: 661 AGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 GVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 649 ----------------GVAARPGFGLSPIFPGGACLGKACGRKRK 677 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 189 bits (480), Expect = 8e-48 Identities = 235/697 (33%), Positives = 263/697 (37%), Gaps = 79/697 (11%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPGAG--LGALGG-GALGPGGKPLKPVPGGLAGAGLG 76 P PG G PG + P G+PG PGA GA G GA G G P P G G Sbjct: 289 PGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPG---- 344 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 FPGA+ G A + ++ G+ G PG G +AG PGA Sbjct: 345 ----------FPGAVGAKGEAGPQGP-RGSEGPQGVRGEPGPPGPAGAAGPA-GNPGADG 392 Query: 137 KPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 +PG G PG+ PGAR P G G PG P G +P APG G Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG-PKGNSGEPGAPGSKGDTGAKGEP 451 Query: 193 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 GP G P P G K G G P TG LP GP G G G G+P GV Sbjct: 452 GPVGVQGPPGPAGEEGKR----GARGEPGPTG-LP---GPPGERGGPGSRGFPGADGV-- 501 Query: 253 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAA 311 A A + G AG G AG PG G +PG G+ G G+P Sbjct: 502 ---AGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG-LPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPGVGVPGAGIPVVPGAGIPGAAVPGV 367 A + G P G GV+G PG AG PG AG VPG PGA P Sbjct: 558 PAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK----AGERGVPGP--PGAVGPAG 611 Query: 368 VSPEAAAKAA-AKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV 426 EA A+ A G R G G P GF G G G PG AG PG GV Sbjct: 612 KDGEAGAQGPPGPAGPAGERGEQGPAGSP-------GFQGLP-GPAGPPGEAGKPGEQGV 663 Query: 427 PGVGGVPGVGISPEAQAAAAAKAAKYGLVP----GVGVAPGVGVAPGVGVAPGVGLAPGV 482 PG G PG + + + + P G APG A G APG APG Sbjct: 664 PGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPG---APGS 720 Query: 483 GVAPGVGVAPGVGVAPGI-GPGGVA--AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 539 APG+ PG A G+ GP G A K A K +R G G PG G Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG-PIGPPGPAGAPG 779 Query: 540 VPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGV 599 G +G G G PG PG A A PG G GA G G G Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA----GPPGADGQPGAKGEPGDAGAK 835 Query: 600 VGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGIPPAAAAKAAK 657 AGP A A G GA G G G G PG G G PP + A Sbjct: 836 GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG-PPGPSGNAGP 894 Query: 658 YGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 G G G GG G G A RPG P PG A Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931 Score = 189 bits (480), Expect = 8e-48 Identities = 242/724 (33%), Positives = 261/724 (36%), Gaps = 106/724 (14%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALG---------- 52 G T AA PG P+ P G PGA+ G P G G Sbjct: 326 GATGAAGPPGPT-------GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378 Query: 53 GGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGL 112 GA GP G P G GA G+ P FPGA P G G Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPG--FPGARGPSGPQ-------------GP 423 Query: 113 GGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARF-PGVGVLPGV 169 GG PG G GA + G K PG V G PG GAR PG LPG Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 170 PTGAGVKPKAPGVGGAFAGIPGV-------GPFGGPQPGVPLGYPIKAPKLPGGYGLPYT 222 P G PG G F G GV G G P P P G P +A + PG GLP Sbjct: 484 PGERG----GPGSRG-FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-PGEAGLPGA 537 Query: 223 TGKL--PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGG 279 G P GP G G G AG G GP A A GAAG G Sbjct: 538 KGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGE 597 Query: 280 AGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVP 337 GVPG PGA+ G G A A + + G A G PGF PG G P Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA-----GSPGFQGLPGPAGPP 652 Query: 338 G-AGVPGV-GVPG-AGIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGV 389 G AG PG GVPG G P GA G PG V G P A GA+ Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDA 712 Query: 390 GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKA 449 G G P G+ G PG G+ G G AG+PG G G G G SP K Sbjct: 713 GAPGAP----GSQGAPGLQ-GMPGERGAAGLPGPKGDRGDAGPKGADGSP-------GKD 760 Query: 450 AKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAA 508 GL +G PG APG G G A G APG PG GP G A Sbjct: 761 GVRGLTGPIG-PPGPAGAPGDKGESGPSGPAGPTGARG---APGDRGEPGPPGPAGFAGP 816 Query: 509 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 568 + + AK + A G G PG AG PG G PG Sbjct: 817 PGADGQPGAKGEPGDAGAKG--------DAGPPGPAGPAGPPGPIGNVGAPG-------- 860 Query: 569 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 628 AK A+ A PG G GA G VG PG AGP A G G AG Sbjct: 861 --AKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGR 918 Query: 629 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 688 G VG G PG G G P A A G G G+ G G L G GF P Sbjct: 919 PG-EVGPPGPPGPAGEKG-SPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGF---P 973 Query: 689 IFPG 692 PG Sbjct: 974 GLPG 977 Score = 163 bits (412), Expect = 6e-40 Identities = 240/776 (30%), Positives = 276/776 (35%), Gaps = 134/776 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA--GLGALGG-------GALGPGGKPLK------PVP 67 P PGG PG P G G PG+ GA G G GP G+ K P P Sbjct: 420 PQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477 Query: 68 GGLAGAGL---GAGLGAFPAVTFPGALVPGGVAD-------AAAAYKAAKAGA-GLGGVP 116 GL G G G FP G P G A A +AG G G+P Sbjct: 478 TGLPGPPGERGGPGSRGFPGAD--GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 117 GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGV 169 G GL S G+ P G PG G PG PG PGAR FPG G Sbjct: 536 GAKGLTGSPGSPGPDGKTG-PPGPAGQDGRPGP-PGP--PGARGQAGVMGFPGPKGAAGE 591 Query: 170 PTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGY-----PIKAPK---LPGGYGL 219 P AG + P PG G G G P P P G P +P LPG G Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 220 PYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFG 267 P GK +P G G +GA G+ G+P GV GP+ A A AK Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711 Query: 268 AGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL 322 AGA G G G+ G+PG +PG G G P A + K G + Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPI 769 Query: 323 VPGGPGFGPGVVGVPGA----------GVPG----VGVPG-AGIPVVPGA-------GIP 360 P GP PG G G G PG G PG AG PGA G P Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 361 G-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 413 G A PG P GA+ G G P GA GFPG G G Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP----GATGFPG-AAGRVG 884 Query: 414 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVA 473 PG +G G G PG G G G P + A + + G PG G +PG A Sbjct: 885 PPGPSGNAGPPGPPGPAGKEG-GKGPRGETGPAGRPGEVG-PPGPPGPAGEKGSPG---A 939 Query: 474 PGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 532 G APG G+ GV PG G G + + + A+ G P Sbjct: 940 DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999 Query: 533 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 592 +G PGL AG PG G PG PG + AK G G GA G Sbjct: 1000 -----MGPPGL---AGPPGESGREGAPGAEGSPGR-DGSPGAKGDRGETGPAGPPGAPGA 1050 Query: 593 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----------GVGGLGVPGV 641 G PG V AG + A A G VGA G G G G+ G Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110 Query: 642 GGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF-GL-SPIFPGG 693 G G+ PP + G +G G G G G + G GL PI P G Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166 Score = 158 bits (399), Expect = 2e-38 Identities = 223/703 (31%), Positives = 258/703 (36%), Gaps = 115/703 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG-----AGLGA 77 P P G PG G+PG PG P G P P P GL G G Sbjct: 122 PRGPAGPPGR--DGIPGQPGLPG------------PPGPPGPPGPPGLGGNFAPQLSYGY 167 Query: 78 GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAG 135 + ++ PG + P G A G G PG G ++G + P+ PG Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGG--AFAGIPGV 192 K G G PG PG R P G G+P AG+ PG+ G F+G+ G Sbjct: 227 GKNGDDGEAGKPG------RPGERGPPGPQGARGLPGTAGL----PGMKGHRGFSGLDGA 276 Query: 193 GPFGGP-----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG---AAGKAGY 244 GP +PG P AP G GLP G+ P GP G G A G AG Sbjct: 277 KGDAGPAGPKGEPGSP--GENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGP 333 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAA 304 P TG P AK AG G G GV G PG PG G AG PA Sbjct: 334 PGPTG--PAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG---PAGN 387 Query: 305 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVVPGA-GI 359 A A A G+ G PGF PG G G PG G PG +G P PG+ G Sbjct: 388 PGADGQPGAKGANGAPGIA-GAPGF-PGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGD 444 Query: 360 PGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 418 GA PG V + A + K GAR G G+P G PG Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP-----------------GPPGER 487 Query: 419 GVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGL 478 G PG G PG GV G P + + A G +PG PG PG Sbjct: 488 GGPGSRGFPGADGVAGPK-GPAGERGSPGPAGPKG-------SPGEAGRPGEAGLPG--- 536 Query: 479 APGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGV 538 A G+ +PG G PG P G A+ Q AG+ + Sbjct: 537 AKGLTGSPGSPGPDGKTGPPG--PAGQDGRPGPPGPPGARGQ--------AGV------M 580 Query: 539 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGAAVP----GVLGGLGALGGV 593 G PG AG PG GVPG PGA+ A K + GA P G G G G Sbjct: 581 GFPGPKGAAGEPGKAGERGVPG---PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA 637 Query: 594 GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAA 653 G PG GPA A + G +GA G G G G PG G+ G PP A Sbjct: 638 GSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR-GERGFPGERGVQG-PPGPAG 695 Query: 654 KAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 696 GA G G G AG G PG P G A L Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738 Score = 150 bits (378), Expect = 5e-36 Identities = 231/719 (32%), Positives = 257/719 (35%), Gaps = 131/719 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--------GALGPGGKPLKPVPGGLAGA 73 P+ P G PG G PG PGA GL G G GP G+ +P P G GA Sbjct: 516 PAGPKGSPGE--AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573 Query: 74 GLGAGLGAFP----AVTFPGAL----VPGGVADAAAAYKAAKAGA--------------- 110 AG+ FP A PG VPG A K +AGA Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE 633 Query: 111 -GLGGVPGVGGLGVSAGAVVPQPGAGVKPGK--VPG-VGLPGVYPGGVLPGARFPGVGVL 166 G G PG GL AG PG KPG+ VPG +G PG P G FPG + Sbjct: 634 QGPAGSPGFQGLPGPAGP----PGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGV 687 Query: 167 PGVPTGAGVKPK--APGVGGAF--AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYT 222 G P AG + APG GA AG PG P PG+ P G GLP Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGA-PGSQGAPGLQ-----GMPGERGAAGLPGP 741 Query: 223 TGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 281 G GP G G+ GK G TG +GP A A +G AG G G Sbjct: 742 KGDRGDA-GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPG 800 Query: 282 VPGVPGAIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 G PG PG G AG G P A A G P GP G VG P Sbjct: 801 DRGEPGP-PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859 Query: 338 GA-------GVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARP 387 GA G PG G PGA V P A PG P + G RP Sbjct: 860 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 388 G-VGVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 435 G VG G P GA G PG G+ G GV G+PG G G G+PG Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQGIAGQRGVVGLPGQRGERGFPGLPGP 978 Query: 436 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV---APGVGLAPGVGVAPGV---- 488 P Q + A + PG PG+ PG APG +PG +PG Sbjct: 979 SGEPGKQGPSGASGERGP--PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDR 1036 Query: 489 ---GVA--PGVGVAPGIGPGGVAAAAKSA----------AKVAAKAQLRAAAGLGA--GI 531 G A PG APG PG V A KS A R AG G Sbjct: 1037 GETGPAGPPGAPGAPG-APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 532 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 591 G G G+ G GL G PG G A+ A PG G G G Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAG-PRGPPGSAGAPGKDG 1154 Query: 592 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPA 650 G+PG + GP G G AG VG G PG G G P A Sbjct: 1155 LNGLPGPIGPPGPR---------------GRTGDAG----PVGPPGPPGPPGPPGPPSA 1194 Score = 118 bits (296), Expect = 2e-26 Identities = 173/542 (31%), Positives = 192/542 (35%), Gaps = 108/542 (19%) Query: 231 GPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKF----------GAGAAGV 273 GP G AG G+ G P G+ GP A + G G Sbjct: 121 GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP 180 Query: 274 LPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYG--------AAAGLVP 324 + G G+PG PGA PG G G G P A+ G AG P Sbjct: 181 MGPSGPRGLPGPPGA-PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG-KP 238 Query: 325 GGPG-FGP----GVVGVPG-AGVPGV-------GVPGA----------GIPVVPGA-GIP 360 G PG GP G G+PG AG+PG+ G+ GA G P PG G P Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298 Query: 361 G----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPG 416 G +PG A A GA G G PT G GFPG VG G G Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG-PTGPAGPPGFPG-AVGAKGEAG 356 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 476 G G G GV G PG P A AA A PG PG A G APG+ Sbjct: 357 PQGPRGSEGPQGVRGEPG----PPGPAGAAGPAGN----PGADGQPG---AKGANGAPGI 405 Query: 477 GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG----AGI 531 APG A G G G PG G G A S AK + G AG Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465 Query: 532 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA--LAAAKAAKYGAAVPGVLGGLGA 589 G G PG G+PG G PG PGA +A K PG G G+ Sbjct: 466 EGKRGARGEPG---PTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS 522 Query: 590 LGGVGIPG--GVVGA----------------GPAAAAAAAKAAAKAAQFGLVGAAGLGGL 631 G G PG G+ GA GP A G G AG+ G Sbjct: 523 PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGF 582 Query: 632 --GVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLG-----GVAARP 682 G G PG G G+ PP A A K G AG G G AG P G G A P Sbjct: 583 PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAG--PAGERGEQGPAGSP 640 Query: 683 GF 684 GF Sbjct: 641 GF 642 Score = 106 bits (265), Expect = 6e-23 Identities = 153/447 (34%), Positives = 167/447 (37%), Gaps = 55/447 (12%) Query: 26 PGGVPGAIPGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAG---------- 72 P G PG P G PG G P G G GA G G+P P P G AG Sbjct: 768 PIGPPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825 Query: 73 ----AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 GA A P A PG + + A AK G G PG G +AG V Sbjct: 826 KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP--GAKGARGSAGPPGATGFPGAAGRV 883 Query: 129 VPQ-PGAGVKPGKVPGVGLP--GVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 185 P P P PG G P G A PG PG P AG K +PG G Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG-SPGADGP 942 Query: 186 FAGIPGV-GPFG-GPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGY----GPGG 234 AG PG GP G Q GV +G P + P LPG G P G P G GP G Sbjct: 943 -AGAPGTPGPQGIAGQRGV-VGLPGQRGERGFPGLPGPSGEPGKQG--PSGASGERGPPG 998 Query: 235 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA--IPGI 292 G G AG P +G + A A GA G G AG PG PGA PG Sbjct: 999 PMGPPGLAGPPGESG--REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP 1056 Query: 293 GGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPGA 349 G AG G A A GA P GP G G G G+ G G G Sbjct: 1057 VGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGL 1116 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 P P G PG P S A + +A GA G+ G+P G G PG Sbjct: 1117 QGPPGP-PGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLP----GPIGPPG-PR 1168 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVG 436 G G G G PG G PG G P G Sbjct: 1169 GRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 85.5 bits (210), Expect = 2e-16 Identities = 122/374 (32%), Positives = 140/374 (37%), Gaps = 45/374 (12%) Query: 23 PSRPGGVPGAI-----PG--------GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGG 69 P+ P G PG I PG G PG +PGA G +G GP G P P G Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA-GRVGPP--GPSGNAGPPGPPG 899 Query: 70 LAGAGLGAG-LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAG 126 AG G G G PG + P G A A AG G PG G+ G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 127 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARF-----PGVGVLPGV--PTGAGVKPKA 179 VV PG + G PG+ P PG P PG PG+ P G + A Sbjct: 960 -VVGLPGQRGERG-FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGA 1017 Query: 180 PGVGGAFA--GIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA 236 PG G+ G PG G G P P G P AP PG G +G G G A Sbjct: 1018 PGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-GAPGAPGPVGPAGKSGDR----GETGPA 1072 Query: 237 GAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 G AG G G GPQ + + G G G G PG PG+ PG G Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS-PGEQGP 1131 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGI 351 +G PA +A A GL GP PG G G P VG PG G Sbjct: 1132 SGASGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPGPRGRTGDAGP-VGPPGPPGPPGP 1188 Query: 352 PVVPGAGIPGAAVP 365 P P AG + +P Sbjct: 1189 PGPPSAGFDFSFLP 1202 Score = 81.6 bits (200), Expect = 2e-15 Identities = 107/349 (30%), Positives = 128/349 (36%), Gaps = 38/349 (10%) Query: 355 PGAGIP-GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 413 PGA +P G P V P+ + + P G P G G PG G Sbjct: 82 PGAEVPEGECCP--VCPDGSESPTDQETTGVEGPKGDTG--PRGPRGPAGPPGRD----G 133 Query: 414 IPGVAGVPGVGGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVG 471 IPG G+PG G PG G PG+G +P+ K+ VPG G PG Sbjct: 134 IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPP 193 Query: 472 VAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQL-----RAAA 525 APG G PG A G +G GP G A K + + A Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253 Query: 526 GL--GAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGALA----AAKAAKY 576 GL AG+PG+ G GL AG G G PG PG + + + Sbjct: 254 GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313 Query: 577 GAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 635 GA P G G GA G G PG AGP A A +A G G+ G G+ Sbjct: 314 GAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV---- 369 Query: 636 LGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 G PG PP A A G G G G G G+A PGF Sbjct: 370 RGEPG-------PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 181 bits (458), Expect = 3e-45 Identities = 231/729 (31%), Positives = 268/729 (36%), Gaps = 109/729 (14%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG P G PG +PG+ G GP G+P + P G G Sbjct: 175 PAGPPG--PPGPPGTSGHPGSPGSP---GYQGPPGEPGQAGPSGPPGP------------ 217 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGVKPGKV 141 PGA+ P G A D + GL G PG+ G G + G + G+ Sbjct: 218 --PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEK 275 Query: 142 PGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ LPG PG G P G +P PG GA G G P P Sbjct: 276 GETGAPGLKGENGLPGENGAPGPMGPRGAPGERG-RPGLPGAAGARGNDGARGSDGQPGP 334 Query: 201 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAA 259 P PG G P + G G G AG+ G G P G GPQ A A Sbjct: 335 PGP----------PGTAGFPGSPG----AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380 Query: 260 AKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAA 319 G+ G +G AG+PG PG + G G A A + K GA Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440 Query: 320 AGLVPGGPGFGPGVVGVPGA----------GVPGV-GVPGA----GIPVVPGA----GIP 360 P G G+ GVPGA G PG G+PGA G P G GIP Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP 500 Query: 361 GAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPG--FGVGVG 412 G P G P AA + + G G G+ G+P G G+ G PG G Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGVAPGV 470 G PG G G G PGV G PG P+ A K + G PG PG G Sbjct: 561 GRPGPPGPSGPRGQPGVMGFPG----PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616 Query: 471 GVAPGV--------GLAP----GVGVAPGVGVAPGVGVAPG-IGPGGVAAA--AKSAAKV 515 PG P G+ PG G PG PG GP G A A A Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676 Query: 516 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGALAAAK 572 A R GL AG PGL G G PG G AG PG AG PG +PG Sbjct: 677 AGAPGERGPPGL-AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG------ 729 Query: 573 AAKYGAAVPGVLGGLGALGGV---GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLG 629 + G PG G G GG G+PG GP A + G GA GL Sbjct: 730 -ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLP 788 Query: 630 GLGVGGLGVPGVGGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 G+ G G PG G G P P A + + G G G G G+ GVA PG Sbjct: 789 GI-AGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG- 846 Query: 685 GLSPIFPGG 693 G P P G Sbjct: 847 GSGPAGPPG 855 Score = 169 bits (427), Expect = 1e-41 Identities = 245/763 (32%), Positives = 272/763 (35%), Gaps = 121/763 (15%) Query: 23 PSRPGGVPGAI----PGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAGL 75 PS P G PGAI P G G PG G L G G GP G P PG G Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--GFPGMKGHRGF 268 Query: 76 GAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPGVGGLGVSAGA--V 128 G PG G+ A + A G G+PG G + GA Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGS 328 Query: 129 VPQPGAGVKPGKVPGVGLPG----VYPGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGV 182 QPG PG G PG V P G PG PG AG + P PG+ Sbjct: 329 DGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGI 388 Query: 183 GGA--------FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPG 233 G+ AGIPG G G P P G AP L GG G P G G Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG-ANGAPGLRGGAGEPGKNG----AKGEP 443 Query: 234 GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV-----PGA 288 G G G+AG P G A K + GA G+ G G PG P Sbjct: 444 GPRGERGEAGIP-----GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498 Query: 289 IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV 344 IPG G AG G P A AA + + G VPGGPG PG G PG+ G P Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDG-----VPGGPGMRGMPGSPGGPGSDGKP-- 551 Query: 345 GVPG----AGIPVVPGAGIPGA--AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 398 G PG +G P PG P V G P+ A K + G G G G P Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611 Query: 399 -----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAA 447 G GG G G G G+ G+PG GG PG G PG P + A A Sbjct: 612 GETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGENGKPG---EPGPKGDAGA 667 Query: 448 KAAKYGLVPGVGVAPGVGVAPGVGVAPGV--GLAP-----GVGVA-----PGVGVAPGVG 495 A G G APG PG+ APG+ G P G G A PG PG+ Sbjct: 668 PGAPGG--KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725 Query: 496 VAPG-------IGPGGVAA--AAKSAAKVAAKAQLRAAAG-LG----AGIP---GLGVGV 538 PG GP G A V K R G +G AG P G G Sbjct: 726 GMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAP 785 Query: 539 GVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGIP 596 G+PG+ G PG G PG PGA K PG G G G G P Sbjct: 786 GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP 845 Query: 597 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----GVGGLGVPGVGGLGGI--PP 649 GG AGP G G G GL G G PG G G PP Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905 Query: 650 AAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 A G+ G+ G G AGQ G PG P PG Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQ---PGEKGSPGAQGPPGAPG 945 Score = 162 bits (410), Expect = 1e-39 Identities = 221/719 (30%), Positives = 251/719 (34%), Gaps = 109/719 (15%) Query: 25 RPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 RPG + P G PG + +PG G G G P P P G G G P Sbjct: 562 RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPG- 143 T PG G D GL G+PG GG PG KPG+ PG Sbjct: 622 PTGPG----GDKGDT-----GPPGPQGLQGLPGTGG----------PPGENGKPGE-PGP 661 Query: 144 ---VGLPGVYPGGV----LPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGP 194 G PG PGG PG R PG+ PG+ GAG P P G AG PG G Sbjct: 662 KGDAGAPGA-PGGKGDAGAPGERGPPGLAGAPGLRGGAG--PPGPEGGKGAAGPPGPPGA 718 Query: 195 FGGP----QPGVPLGYPIKAPK----LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 G P PG G PK PGG G GK GP G G G AG P Sbjct: 719 AGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK-DGPRGPTGPIGPPGPAGQPG 777 Query: 247 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAA 306 G G A A + G G G AG PG PG GG G P Sbjct: 778 DKGEG--GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE 835 Query: 307 AAAAAKAAKYGAAAGLVPGGP---------GFGPGVVGVPGA-GVPG------------- 343 A G + P GP GPG G PGA G+PG Sbjct: 836 GGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGP 895 Query: 344 VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGAR--PG----VGVGGIPTY 397 G PG P P PGV P+ A + GA+ PG +G+ GI T Sbjct: 896 SGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI-TG 954 Query: 398 GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPG 457 G G PG G G PG GV G G PG G+ G P Q + G Sbjct: 955 ARGLAGPPGM-PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG--------LAG 1005 Query: 458 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI--GPGGVAAAAKSAAKV 515 PG PG PG +PG G +PG APG PG V A KS + Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065 Query: 516 AAKAQLRAAAGLGAGIPGLGVGVGVP---GLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 572 + AG AG PG G P G G G AG+ G PG Sbjct: 1066 ES-----GPAG-PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG------ 1113 Query: 573 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGL 631 PG G G G +G PG GP + + G +G G G Sbjct: 1114 ----NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR 1169 Query: 632 GV-GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 689 G G G PG G G P A G G + G G+ GG A P +G P+ Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE-KAGGFA--PYYGDEPM 1225 Score = 131 bits (329), Expect = 2e-30 Identities = 171/544 (31%), Positives = 204/544 (37%), Gaps = 89/544 (16%) Query: 170 PTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 228 P G P PG+ G G PG+ G G P P G P P Y Y + + Sbjct: 104 PQGPKGDPGPPGIPGR-NGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162 Query: 229 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 288 G GG+AG G AG P GP G +G G G G PG Sbjct: 163 GVAVGGLAGYPGPAGPP-----GPPGP------------PGTSGHPGSPGSPGYQGPPGE 205 Query: 289 IPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPG-AGVPGV 344 PG G +G G P A + A K + G PG PG PG G+ G AG+PG Sbjct: 206 -PGQAGPSGPPGPPGAIGPSGPAGKDGESGR-----PGRPGERGLPGPPGIKGPAGIPGF 259 Query: 345 -GVPG-------------AGIPVVPGA-GIPGA-AVPGVVSPEAA---------AKAAAK 379 G+ G G P + G G+PG PG + P A AA Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319 Query: 380 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 GAR G G P G GFPG G G G AG PG G PG G PG P Sbjct: 320 RGNDGARGSDGQPG-PPGPPGTAGFPG-SPGAKGEVGPAGSPGSNGAPGQRGEPG----P 373 Query: 440 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 499 + A A PG+ +PG G PG APG+ A G G APG Sbjct: 374 QGHAGAQGPPGP----PGINGSPGGKGEMGPAGIPG---APGLMGARGPPGPAGANGAPG 426 Query: 500 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 559 + GG K+ AK + R G AGIP GVPG G G G P Sbjct: 427 L-RGGAGEPGKNGAK--GEPGPRGERG-EAGIP------GVPG---AKGEDGKDGSPGEP 473 Query: 560 GFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQ 619 G +PGA A + GA PG G G G G G G A AA + + Sbjct: 474 GANGLPGA-----AGERGA--PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526 Query: 620 FGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 679 G+ G G+ G+ G G PG G G PP + ++ + G G G G G G Sbjct: 527 DGVPGGPGMRGM-PGSPGGPGSDGKPG-PPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK 584 Query: 680 ARPG 683 G Sbjct: 585 GNDG 588 Score = 131 bits (329), Expect = 2e-30 Identities = 181/559 (32%), Positives = 204/559 (36%), Gaps = 87/559 (15%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPG-AGLGALGGGA--LGPGGKPLKPVPGGLAGAGL 75 P G PGA G G PG PG AG L GGA GP G P G GA Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG 720 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAG 135 GL P G PG D K G G GVPG G G + P PG Sbjct: 721 TPGLQGMPGER-GGLGSPGPKGD-----KGEPGGPGADGVPGKDGPRGPTGPIGP-PGPA 773 Query: 136 VKPGK--------VPGVGLPGVYPG-----GVLPGARFPGVGVLPGVPTGAGVKPKAPGV 182 +PG +PG+ P PG G A FPG G P G G + APG Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER-GAPGE 832 Query: 183 GGAFAGIPGV-GPFGGPQPGVPLG-YPIK----APKLPGGYGLPYTTGKLPYGYGPGGVA 236 G G PGV GP GG P P G +K +P PG G P G LP G G Sbjct: 833 KGE-GGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG-LPGPPGSNGNP 890 Query: 237 GAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G +G P G G A + + K AG G G G PG PG + GI Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL-GI 949 Query: 293 GGIAGV-------------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA 339 GI G G+P + K G + P GP PG+ G A Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT--A 1007 Query: 340 GVPG-VGVPGA-GIPVVPGA----------GIPGA-AVPGVVSPEAAAKAAAKAAKYGAR 386 G PG G PG+ G+P G+ G PGA PG P A K+ G Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067 Query: 387 PGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 441 G G P G+ G PG G G G AG+ G G PG G PG P Sbjct: 1068 GPAGPAGAPG-PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG-SPGPAG 1125 Query: 442 QAAAAAKAAKYGLVPGVGVA-----------PGVGVAPGVGVAPGVGLAPGVGVAPGVGV 490 Q A G VG + PG PG G + G PG Sbjct: 1126 QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185 Query: 491 APGVGVAPGIGPGGVAAAA 509 PG APG GGV AAA Sbjct: 1186 PPGPPGAPGPCCGGVGAAA 1204 Score = 129 bits (324), Expect = 9e-30 Identities = 166/529 (31%), Positives = 196/529 (37%), Gaps = 70/529 (13%) Query: 198 PQPGVPLG-------YPIKAPKLP-------GGYGLPYTTGKLPYGYGPGGVAGAAGKAG 243 P P +P G P AP P G G P G +P G G+ G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPG 133 Query: 244 YPTGTGV------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 297 P G+ GPQ + K G G+ G AG PG PG PG G G Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSGHPG 192 Query: 298 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPG----AG 350 G+P +A P GP PG +G G AG G G PG G Sbjct: 193 SPGSPGYQGPPGEPGQAG---------PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243 Query: 351 IPVVPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG-----VGA 401 +P PG AGIPG PG+ + + GA G G+P +G Sbjct: 244 LPGPPGIKGPAGIPG--FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 461 G PG G G+PG AG G G G G PG P + AK G V G + Sbjct: 302 RGAPG-ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK-GEVGPAG-S 358 Query: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVAAAAKSAAKVAA 517 PG APG PG G PG PG+ +PG +GP G+ A + A Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPG---PPGINGSPGGKGEMGPAGIPGA---PGLMGA 412 Query: 518 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 577 + A GA PGL G G PG G PG G G VPG A + K G Sbjct: 413 RGPPGPAGANGA--PGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPG--AKGEDGKDG 468 Query: 578 A-AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 636 + PG G GA G G PG AGP A + G G G G G Sbjct: 469 SPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG-EPGRD 527 Query: 637 GVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 GVPG G+ G+P P K G G G G G G +PG Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPG 576 Score = 96.7 bits (239), Expect = 7e-20 Identities = 136/455 (29%), Positives = 155/455 (34%), Gaps = 72/455 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALG-PGGKPLKPVPGGLAGAGLGAGLGA 81 P G G+ P G PG G G GA G PG + L PG G G+ Sbjct: 839 PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 PG P G A G G PGV G AG QPG PG Sbjct: 899 ------PGKDGPPGPA----------GNTGAPGSPGVSGPKGDAG----QPGEKGSPGAQ 938 Query: 142 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPG 201 G PG + GAR G+ PG+P G P GV G +G PG G Sbjct: 939 GPPGAPGPLGIAGITGAR--GLAGPPGMPGPRG-SPGPQGVKGE-SGKPGANGLSGE--- 991 Query: 202 VPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 261 + P PG GLP G G AG G+ G P G+ + + Sbjct: 992 -------RGP--PGPQGLP----------GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKG 1032 Query: 262 AAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA 320 + G+ PG GA G PG PG + G G A A A A GA Sbjct: 1033 DRGENGS------PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086 Query: 321 GLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAK 379 P GP G G GA G+ G G P PGA PG P A Sbjct: 1087 ---PQGPRGDKGETGERGA----AGIKGHRGFPGNPGA-------PGSPGPAGQQGAIGS 1132 Query: 380 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G R VG G P G G PG +G G G G G G PG G PG P Sbjct: 1133 PGPAGPRGPVGPSGPPGKD-GTSGHPG-PIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP 1190 Query: 440 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 474 A + G+G G AP G P Sbjct: 1191 GAPGPCCGGVGA-AAIAGIGGEKAGGFAPYYGDEP 1224 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 176 bits (446), Expect = 7e-44 Identities = 227/763 (29%), Positives = 289/763 (37%), Gaps = 137/763 (17%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--GVPGAI----PGGVPGGVFYPGA---------- 46 G+T A PG HP PG G PG++ G PGGV +PG+ Sbjct: 553 GMTGRAGSPG------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPP 606 Query: 47 GLGALGG----------------GALGPGGKPLK--PVPGGLAGAGLGAGLGAFPAVT-- 86 G G G G GP G+P K P+PG GL G FP Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG-FPGPQGD 665 Query: 87 --FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 FPG PG + G G G PG G+ G + P PG +PG Sbjct: 666 RGFPGT--PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP-PGTPGRPGFNGLP 722 Query: 145 GLPGVY-----PGGVLPGARFPGVGVLPGVPTGAGVK-----PKAPGVGGAFA--GIPGV 192 G PGV PG LPG + G+ LPG+P G K P PG GA G+ G+ Sbjct: 723 GNPGVQGQKGEPGVGLPGLK--GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGI 780 Query: 193 ----GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 GP G P PGVP P A PGG G P +G P G+ G G G+ Sbjct: 781 RGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSG-------PPGIKGEKGFPGF 833 Query: 245 PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVGTPAA 303 P GP+ A +G G LPG GA G+PG PG+ +G + G P + Sbjct: 834 PGLDMPGPKGDKGAQGLPGITGQSGLPG-LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS 892 Query: 304 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAA 363 A + G GP PG+ G G VG+PG Sbjct: 893 PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG----DVGLPGK-------------- 934 Query: 364 VPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 PG + + G + +G P G+ G P G G+PG G G Sbjct: 935 -PGSMDKVDMGSMKGQKGDQGEKGQIG----PIGEKGSRGDP----GTPGVPGKDGQAGQ 985 Query: 424 GGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-VPGVGVAPGVGVAPGVGVAPGVGLAPGV 482 G PG G PG+ +P A K + G+ +PG GV PG +PG+ G Sbjct: 986 PGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGA 1045 Query: 483 GVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVG 537 G PG+G+ PG+ G G+A S + K + G+ G+ G Sbjct: 1046 KGEKGQAGPPGIGI-PGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104 Query: 538 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG 597 VG PG G+PG G+PG +PG K A +PG G G G G PG Sbjct: 1105 VGYPG---SPGLPGEKGDKGLPGLDGIPG-------VKGEAGLPGTPGPTGPAGQKGEPG 1154 Query: 598 GVVGAGPAAAAAAAKAAAKAAQF-GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA- 655 P +A + F G GA G G G +G PG+ G GIP + + Sbjct: 1155 S--DGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG-SKGEVGFPGLAGSPGIPGSKGEQGF 1211 Query: 656 ----AKYGAAGLGGVLGGAGQFPLG--GVAARPGFGLSPIFPG 692 G GL G G A + P G G +PG P PG Sbjct: 1212 MGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGL---PGLPG 1251 Score = 174 bits (442), Expect = 2e-43 Identities = 218/716 (30%), Positives = 271/716 (37%), Gaps = 98/716 (13%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAG 78 P RPG G GA+ G PG F G + G G +GP G P +P GL G G Sbjct: 672 PGRPGLPGEKGAV--GQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQG 729 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAG--AVVPQPGAGV 136 P V PG G+ K G+ GVPG G G + +PG Sbjct: 730 QKGEPGVGLPGLKGLPGLPGIPGT-PGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788 Query: 137 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIPGV-- 192 PG V G+PG+ P PGAR P G P +G PG+ G F G PG+ Sbjct: 789 LPGSVGSPGVPGIGP----PGARGPPGGQGPPGLSGP------PGIKGEKGFPGFPGLDM 838 Query: 193 -GPFG--GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 GP G G Q + P LPG G P G P G GV G G+ G P Sbjct: 839 PGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPG-FPGSKGEMGVMGTPGQPGSP---- 893 Query: 250 VGPQAAAAAAAKAAAKFGAGAAGVL--PGV----GGAGVPGVPGAIPGI----------- 292 GP A + G++G PG+ G G+PG PG++ + Sbjct: 894 -GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGD 952 Query: 293 ----GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV--G 345 G I +G + K G A GP PG+ G PGA G+PG Sbjct: 953 QGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012 Query: 346 VPGAGIPVVPGA-GIPGAAVPGVV-SPEAAAKAAAKAAKYGARP-GVGVGGI--PTYGVG 400 V G G+P PG G+PG +PG SP AK K A P G+G+ G+ G Sbjct: 1013 VGGMGLPGTPGEKGVPG--IPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQG 1070 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 460 GFPG G G G G+PG+ G PG+ G PG P + K K GL PG+ Sbjct: 1071 IAGFPG-SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDK-GL-PGLDG 1127 Query: 461 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA---PGIGPGGVAAAAKSAAKVAA 517 PGV G+ PG G PG PG PG+ G + + Sbjct: 1128 IPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGS 1187 Query: 518 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 577 K ++ G PGL G+PG G G G G +PG+ G Sbjct: 1188 KGEV--------GFPGLAGSPGIPG---SKGEQGFMGPPGPQGQPGLPGS--------PG 1228 Query: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGG 635 A G G G G G+PG GP G GA G+ G G Sbjct: 1229 HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGF 1288 Query: 636 LGVPGVGGLGGI--------PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G+PG+GG GI PP G GL G+ G G + G PG Sbjct: 1289 QGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344 Score = 144 bits (362), Expect = 4e-34 Identities = 224/739 (30%), Positives = 268/739 (36%), Gaps = 116/739 (15%) Query: 22 HPSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLG 76 +P PG +PG IPG G PG PG G LGP G P P P GL G Sbjct: 101 YPGNPG-LPG-IPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGD 158 Query: 77 AG--LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--- 131 G LG P + G + G+ G PG GL G V P Sbjct: 159 PGEILGHVPGMLLKGE----------------RGFPGIPGTPGPPGLPGLQGPVGPPGFT 202 Query: 132 --PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP-------GV 182 PG PG G G+ G GV PGVP A V+ K G Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQ 262 Query: 183 GG--AFAGIPGVGPFGGPQPGVPLGYPIK--------APKLPGGYGLPYTTGKLPYGYGP 232 G F G+PGVG G P P G P K +P PG G P G+ GP Sbjct: 263 KGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR----QGP 318 Query: 233 GGVAGAAGKAGYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPG 291 G G AG G P G GP + + G G G G PG+PG PG Sbjct: 319 QGEKGEAGPPGPPGIVIGTGP------LGEKGERGYPGTPGPRGEPGPKGFPGLPGQ-PG 371 Query: 292 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV---- 344 G+ G A + G +PG G PG G PG G PG Sbjct: 372 PPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGI 431 Query: 345 -----GVPG-AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPG-------VG 390 G PG G P +PG PG G + + Y PG +G Sbjct: 432 VECQPGPPGDQGPPGIPGQ--PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIG 489 Query: 391 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG---VGISPEAQAAAAA 447 G P G G PG GV G+PG G PG+ G PG G PG + + Sbjct: 490 FPGQPG-AKGDRGLPGRD-GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG 547 Query: 448 KAAKYGLV-----PGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIG 501 + G+ PG PG+ PG +PG VGL G GVG G G Sbjct: 548 FPGQPGMTGRAGSPGRDGHPGL---PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG 604 Query: 502 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 561 P G A + K Q A G G PGL G PG V +PG G+PG Sbjct: 605 PPGYG----PAGPIGDKGQ--AGFPGGPGSPGLPGPKGEPGKIV--PLPGPPGAEGLPGS 656 Query: 562 GAVPGALAAAKAAKYGAAVPGVLGGLGALG--GVGIPG--GVVGA-GPAAAAAAAKAAAK 616 PG + PG+ G GA+G G+G PG G G G + Sbjct: 657 PGFPGP-QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGR 715 Query: 617 AAQFGLVGAAGL-GGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQF 673 GL G G+ G G G+G+PG+ GL G+P P + G G+ G G G Sbjct: 716 PGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPP 775 Query: 674 PLGGVAARPGFGLSPIFPG 692 L G+ PG P PG Sbjct: 776 GLQGIRGEPG---PPGLPG 791 Score = 144 bits (362), Expect = 4e-34 Identities = 215/702 (30%), Positives = 260/702 (37%), Gaps = 179/702 (25%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87 G PG P G+PG V PG G G G G P P GL+G G FP F Sbjct: 782 GEPG--PPGLPGSVGSPGVP----GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG--F 833 Query: 88 PGALVPGGVADAAAAYKAAKAGA-------GLGGVPGVGGLGVSAG--AVVPQPGAGVKP 138 PG +PG D A G G G PG+ G S G V+ PG P Sbjct: 834 PGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSP 893 Query: 139 GKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVP------------------ 170 G V GLPG PG+ P G LPG P Sbjct: 894 GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953 Query: 171 -----------TGAGVKPKAPGVGG--AFAGIPGV-GPFGGP----QPGVPLGYPIKAPK 212 G+ P PGV G AG PG GP G P PG P G P PK Sbjct: 954 GEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP-GLP--GPK 1010 Query: 213 -LPGGYGLPYTTGKL-------PYGY----GPGGVAGAAGKAGYPTGTGV-------GPQ 253 GG GLP T G+ P G G G G G+AG P G G+ G Q Sbjct: 1011 GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG-PPGIGIPGLRGEKGDQ 1069 Query: 254 AAAAAAAKAAAKFGAGAAGV--LPG----------VGGAGVPGVPG-----AIPGIGGIA 296 A K G+ G+ +PG VG G PG+PG +PG+ GI Sbjct: 1070 GIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIP 1129 Query: 297 GV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG--------- 343 GV G P A + + G+ +PG G G G+PG G PG Sbjct: 1130 GVKGEAGLPGTPGPTGPAGQKGEPGSDG--IPGSAG-EKGEPGLPGRGFPGFPGAKGDKG 1186 Query: 344 ----VGVPG-AGIPVVPGA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVG 390 VG PG AG P +PG+ G PG PG+ A K + G + G Sbjct: 1187 SKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR-GPQGQPG 1245 Query: 391 VGGIPTYGVGAGGFPGF-GV----------GVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 + G+P +G G PG GV G G+PG G PG G+PG+GG PG+ Sbjct: 1246 LPGLPG-PMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGI---- 1300 Query: 440 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 499 +K + P PGV PG G+ G+ G PG PG Sbjct: 1301 --------TGSKGDMGP-----PGV---PGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPG 1344 Query: 500 -IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGV 558 GP G K + GL G+PG GV GL G+PG G+ Sbjct: 1345 PPGPPGPYDIIKGEPGLPGPEGPPGLKGL-QGLPGPKGQQGVTGL---VGIPG---PPGI 1397 Query: 559 PGFGAVPGALAAAKAAKYGAAVP-GVLGGLGALGGVGIPGGV 599 PGF PG + + G A P G G G G G+PG + Sbjct: 1398 PGFDGAPG-----QKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1434 Score = 117 bits (294), Expect = 3e-26 Identities = 150/477 (31%), Positives = 185/477 (38%), Gaps = 89/477 (18%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALG--PGGKPLKPVPGGLAGAGLGAG 78 P +PG P PG G PG PG G++GG L PG K + +PG GL Sbjct: 986 PGQPG--PKGDPGISGTPGAPGLPGPK-GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGD 1042 Query: 79 LGAFPA---VTFPGALVPG--------GVAD--AAAAYKAAKAGAGLGGVPGVGGLGVSA 125 GA PG +PG G+A + K K G+ G+PG GL S Sbjct: 1043 KGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSP 1102 Query: 126 GAVVPQPGAGVKPGK-----VPGV-GLPGVYPGGVLPGARFP-------GVGVLPGVPTG 172 G+V PG+ PG+ +PG+ G+PGV LPG P G G+P Sbjct: 1103 GSV-GYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGS 1161 Query: 173 AGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 232 AG K + G F G PG G + V P L G G+P + G+ + GP Sbjct: 1162 AGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF------PGLAGSPGIPGSKGEQGF-MGP 1214 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPGVGGA----GVPGVP 286 G G G G P GP+ + G G LPG+ G G PG P Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWP 1274 Query: 287 GAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GV 341 GA PG+ G G G P + G PG PGF G G+PG G+ Sbjct: 1275 GA-PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-----PGVPGF-QGPKGLPGLQGI 1327 Query: 342 PG----VGVPGA-GIPVVPGA--------GIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 388 G GVPGA G+P PG G PG +PG P G + Sbjct: 1328 KGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPG--LPGPEGPPGLKGLQGLPGPKGQQGV 1385 Query: 389 VGVGGIPTYGVGAGGFPGFG-----------VGVGGIPGVAGVPGVGGVPGVGGVPG 434 G+ GIP G G PGF G G G G PG G+PG G PG Sbjct: 1386 TGLVGIP----GPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG 1438 Score = 90.1 bits (222), Expect = 6e-18 Identities = 149/507 (29%), Positives = 173/507 (34%), Gaps = 81/507 (15%) Query: 211 PKLPGGYGLPYTTGKLPYG-YGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 268 P L G G P G P G GP G G G+ G P G GP Sbjct: 54 PGLQGVIGFPGMQG--PEGPQGPPGQKGDTGEPGLPGTKGTRGPP--------------- 96 Query: 269 GAAGVLPGVGGAGVPGVPG--------AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA 320 GA+G G G+PG+PG IPG G G P A Sbjct: 97 GASGY---PGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGN------- 146 Query: 321 GLVPGGPGFGPGVVGVPG---AGVPGVGVPG----AGIPVVPG-AGIPGAAVPGVVSPEA 372 PG PG PG+ G PG VPG+ + G GIP PG G+PG + G V P Sbjct: 147 ---PGPPGL-PGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPG--LQGPVGPPG 200 Query: 373 AAKAAAKAAKYGARPGVGVGGIPTYG-VGAGGFPGFGVGVGGIPGVA-----------GV 420 G G G+ G G G G G G+PG A G Sbjct: 201 FTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVS-GPPGVPGQAQVQEKGDFATKGE 259 Query: 421 PGVGGVPGVGGVPGVGISPE-AQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA 479 G G PG G+PGVG E + K K G G +PG PG PG+ Sbjct: 260 KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDG-DKGEKGSPGFPGEPGY---PGLIGR 315 Query: 480 PGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGV 538 G G PG G+ G GP G K R G G PGL Sbjct: 316 QGPQGEKGEAGPPGPPGIVIGTGPLG----EKGERGYPGTPGPRGEPG-PKGFPGLPGQP 370 Query: 539 GVPGLGV--GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 596 G PGL V AG PG G G PG + + G +PG G G G G Sbjct: 371 GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDG--LPGPPGSPGPPGQPGYT 428 Query: 597 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAA 656 G+V P Q G +G G G + + G G PP Sbjct: 429 NGIVECQPGPPGDQGPPGI-PGQPGFIGEIGEKGQKGESCLICDIDGYRG-PPGPQGPPG 486 Query: 657 KYGAAGLGGVLGGAGQFPLGGVAARPG 683 + G G G G G GVA PG Sbjct: 487 EIGFPGQPGAKGDRGLPGRDGVAGVPG 513 Score = 78.2 bits (191), Expect = 2e-14 Identities = 120/418 (28%), Positives = 147/418 (35%), Gaps = 78/418 (18%) Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP----GVVGVPGA-GVPGVGVPGAGIPVVP 355 PAA ++AA G AG G G GV G G G+PG+ Sbjct: 13 PAALLLHEEHSRAAAKGGCAG-----SGCGKCDCHGVKGQKGERGLPGL----------- 56 Query: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAGGFPGFGVGV 411 G+ G PG+ PE + G PG+ G G P GA G+PG Sbjct: 57 -QGVIG--FPGMQGPEGPQGPPGQKGDTG-EPGLPGTKGTRGPP----GASGYPGN---- 104 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG- 469 PG+ G+PG G PG G+PG G E + PG PG+ PG Sbjct: 105 ---PGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGE 161 Query: 470 -VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGL 527 +G PG+ L G PG+ PG PG+ GP G + Sbjct: 162 ILGHVPGM-LLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQM 220 Query: 528 GAGIPGLGVGVGVPGLGVGAGVPGLGV--------------GAGVPGFGAVPGALAAAKA 573 G G G G+ GVPG G PGF +PG + Sbjct: 221 GLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEP 280 Query: 574 AKYG-AAVPGVLGGLGALGGVGIPG-----GVVG-AGPAAAAAAAKAAAKAAQFGLVGAA 626 K G PG G G G G PG G++G GP A G G Sbjct: 281 GKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEA---------GPPGPP 331 Query: 627 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 G+ +G G LG G G G P K G GL G G G P+ G A PGF Sbjct: 332 GI-VIGTGPLGEKGERGYPGTPGPRGEPGPK-GFPGLPGQPGPPG-LPVPGQAGAPGF 386 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 173 bits (439), Expect = 4e-43 Identities = 251/758 (33%), Positives = 292/758 (38%), Gaps = 125/758 (16%) Query: 23 PSRPGGVPGAIPGGVPG--GVF---YPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGL 75 P+ P G PG P G PG G F Y G G+G G G +GP G P G AGA Sbjct: 58 PTGPPGPPG--PPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP------GAAGAPG 109 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSAGAVVPQPGA 134 G PA PG PG A A A G AG G PG G G V PQ GA Sbjct: 110 PQGFQG-PAGE-PGE--PGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ-GA 164 Query: 135 GVKPGKVPGV-GLPGVYPGGVLPGAR----FPGVGVLPGVP--------TGAGVKP---- 177 PG PG+ G G+ L G + PGV PG P TGA P Sbjct: 165 RGFPG-TPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERG 223 Query: 178 --KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPG 233 APG GA VGP G P G PI + PG G P G++ GP Sbjct: 224 RVGAPGPAGARGSDGSVGPVG------PAG-PIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276 Query: 234 GVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPG 291 G AG G+ G P +G VGP A AK GAAG LPGV GA G+PG P IPG Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK---GAAG-LPGVAGAPGLPG-PRGIPG 331 Query: 292 IGGIAG-------VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-----FGP----GVVG 335 G AG VG P A + + + G+A P GP GP G G Sbjct: 332 PVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391 Query: 336 VPG----AGVPGV-GVPG----AGIPVVPG----------------AGIPGAAVPGVVSP 370 PG G PG G+PG AG+ PG AG PG PG++ P Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGE--PGLMGP 449 Query: 371 EAAAKAAAKAAKYGARPGVGVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 + G VG+ GI P GA G PG +G G G G PG G Sbjct: 450 RGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPG-NIGFPGPKGPTGDPGKNG 508 Query: 426 VPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGV-----APGVGVAPG-VGVAPGVG 477 G G+ G P+ A G+ G G PG PG G A VG Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568 Query: 478 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGV 536 G+ G+ G GP G + AA + ++ G G PG+ Sbjct: 569 KPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 628 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 596 VG G +G+PG AG+PG G + PG G GA G VG P Sbjct: 629 AVGTAGPSGPSGLPGERGAAGIPGGKGEKG----EPGLRGEIGNPGRDGARGAPGAVGAP 684 Query: 597 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAA 656 G G A AA A A G G G G G G G G G P A + A Sbjct: 685 GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVG-PAGPNGFAGPAGAAGQPGAKGERGA 743 Query: 657 KYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 K G G GV+G G P+G AA P P P G+ Sbjct: 744 K-GPKGENGVVGPTG--PVG--AAGPAGPNGPPGPAGS 776 Score = 162 bits (409), Expect = 1e-39 Identities = 223/726 (30%), Positives = 260/726 (35%), Gaps = 87/726 (11%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL- 79 P PG G GA+ P G P +G G GP G P P GL GA AGL Sbjct: 258 PGAPGPKGEIGAVGNAGPAGPAGPRGEVGL--PGLSGPVGPPGNPGANGLTGAKGAAGLP 315 Query: 80 GAFPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQ--PGAG 135 G A PG +PG V A A G G G G G G+ PQ PG Sbjct: 316 GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375 Query: 136 VKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGV 192 + GK G G PG R PG LPG AGV P + G G AG+ G Sbjct: 376 GEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP-AGVRGP 434 Query: 193 -GPFGGP-QPGV--PLGYP-----IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 243 G G P +PG+ P G P I G GLP G+ P GP G G G G Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGR-PGPIGPAGARGEPGNIG 493 Query: 244 YPTGTG----------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 +P G G + A A+ G GV G G G PG PG Sbjct: 494 FPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPG 553 Query: 288 --AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV 344 +PG G AG VG P + +G P GP G G GA P Sbjct: 554 FQGLPGPSGPAGEVGKPG---------ERGLHGEFGLPGPAGPRGERGPPGESGAAGP-T 603 Query: 345 GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 404 G G+ P P PGVV A + + G R G+ G G G G Sbjct: 604 GPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPG----GKGEKGE 659 Query: 405 PGFGVGVG--GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAP 462 PG +G G G G PG G PG G G +A AA A G G Sbjct: 660 PGLRGEIGNPGRDGARGAPGAVGAPGPAGATG----DRGEAGAAGPAGPAGPRGSPGERG 715 Query: 463 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 522 VG A G A G A G G G +GP G AA A Sbjct: 716 EVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP-- 773 Query: 523 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 582 A + G PG+ G PG G PG +G PG P A + + G Sbjct: 774 AGSRGDGGPPGM---TGFPGAAGRTGPPGPSGISGPPG----PPGPAGKEGLRGPRGDQG 826 Query: 583 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----------G 632 +G G +G VG PG GP+ A A GL+GA G+ GL G Sbjct: 827 PVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPG 886 Query: 633 VGG-LGVPGVGGLGGIP-----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGL 686 V G +G PG G+ G P P A GA G G G G G +PG Sbjct: 887 VAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKG 946 Query: 687 SPIFPG 692 +PG Sbjct: 947 ERGYPG 952 Score = 159 bits (403), Expect = 6e-39 Identities = 224/708 (31%), Positives = 261/708 (36%), Gaps = 83/708 (11%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG G PG PGA A G +GP G P G+ G AG P + Sbjct: 392 PPGPPGL--RGSPGSRGLPGADGRA---GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 86 TFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 P L PG + A K G G+ G PG G + G +PG PG Sbjct: 447 MGPRGL-PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG----EPGNIGFPGPKGPT 501 Query: 145 GLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPFGG-PQ 199 G PG G A G PG GA P GV G G PG F G P Sbjct: 502 GDPG--KNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPG 559 Query: 200 PGVPLGYPIKAPK--LPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTG------- 249 P P G K + L G +GLP G P G GP G +GAAG G P G+ Sbjct: 560 PSGPAGEVGKPGERGLHGEFGLPGPAG--PRGERGPPGESGAAGPTG-PIGSRGPSGPPG 616 Query: 250 ----------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG 297 VG A + + GAAG+ G G G PG+ G I PG G G Sbjct: 617 PDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARG 676 Query: 298 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPG 356 G A A A + GAA P GP PG G G P AG PG Sbjct: 677 APGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPG 736 Query: 357 A-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAGGFPGF 407 A G GA P GVV P AA A G PG G GG P G GFPG Sbjct: 737 AKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP-PGPAGSRGDGGPP----GMTGFPG- 790 Query: 408 GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVG 465 G G PG +G+ G G PG G G+ P + + G V PG G Sbjct: 791 AAGRTGPPGPSGISGPPGPPGPAGKEGLR-GPRGDQGPVGRTGEVGAVGPPGFAGEKGPS 849 Query: 466 VAPGVGVAPGVGLAPGVGVAPGVGVAPG-------VGVAPGIG-PGGVAAAAKSAAKVAA 517 G PG G+ APG+ PG GVA +G PG + A A+ Sbjct: 850 GEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPP 909 Query: 518 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 577 A + G+ G PG G PG G PG G G PG + A Sbjct: 910 GAV--GSPGVN-GAPGEAGRDGNPG---NDGPPGRDGQPGHKGERGYPGNIGPVGA---- 959 Query: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637 A PG G +G G G G +GP A A + G+ G G G G G Sbjct: 960 AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG-EKGPRG 1018 Query: 638 VPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 +PG+ G G+ P A GA G G G G G A + G Sbjct: 1019 LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG 1066 Score = 156 bits (394), Expect = 7e-38 Identities = 218/691 (31%), Positives = 258/691 (37%), Gaps = 108/691 (15%) Query: 54 GALGPGGKPLKPVPGGLAGA------GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 G GP G P P P GL G G G GLG P G + P G AA A + Sbjct: 57 GPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM----GLMGPRGPPGAAGA-PGPQ 111 Query: 108 AGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLP 167 G G PG G AGA P AG PGK G PG PG PG R GV+ Sbjct: 112 GFQGPAGEPGEPGQTGPAGARGP---AG-PPGKAGEDGHPGK-PGR--PGER----GVVG 160 Query: 168 GVPTGAGVKPKAPGVGGAFAGIPGVGPFGG--PQPGVPLGYPIKA-PKLPGGYGLPYTTG 224 P GA P PG+ G F GI G G QPG P +K P PG G P TG Sbjct: 161 --PQGARGFPGTPGLPG-FKGIRGHNGLDGLKGQPGAP---GVKGEPGAPGENGTPGQTG 214 Query: 225 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 284 G+ G G+ G P GP A + G G +G AG PG Sbjct: 215 AR-------GLPGERGRVGAP-----GPAGARGSDGSV------GPVGPAGPIGSAGPPG 256 Query: 285 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AG 340 PGA G I VG A A + G + P GP PG G+ G AG Sbjct: 257 FPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSG---PVGPPGNPGANGLTGAKGAAG 313 Query: 341 VPGVGVPGAGIPVVPG-AGIPG-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVG 392 +PGV AG P +PG GIPG G+V A + ++ G G Sbjct: 314 LPGV----AGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQ 369 Query: 393 GIPTYG-----VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAA-- 445 G P G G G G G PG+ G PG G+PG G GV P ++ A+ Sbjct: 370 GPPGPSGEEGKRGPNGEAG-SAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP 428 Query: 446 ---------AAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG-VGVAPGVG 495 A + + GL+ G+ G G VGL PG+ PG +G A G Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGL-PGIDGRPGPIGPAGARG 487 Query: 496 VAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGV 554 IG G K K A GA G G G PG G G Sbjct: 488 EPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQG 547 Query: 555 GAGVPGFGAVPGALA-AAKAAKYGA-------AVPGVLGGLGALGGVGIPGGVVGAGPAA 606 G PGF +PG A + K G +PG G G G G G GP Sbjct: 548 PPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIG 607 Query: 607 AAAAAKAA---AKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 663 + + + G+VGA G G G G+PG G GIP K G GL Sbjct: 608 SRGPSGPPGPDGNKGEPGVVGAVGTAGPS-GPSGLPGERGAAGIPGGKGEK----GEPGL 662 Query: 664 GGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 G +G G+ G PG +P P GA Sbjct: 663 RGEIGNPGR---DGARGAPGAVGAP-GPAGA 689 Score = 153 bits (387), Expect = 5e-37 Identities = 231/739 (31%), Positives = 259/739 (35%), Gaps = 109/739 (14%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGK 61 GL A R GV+ G PG+ P GV P G G G +GP G Sbjct: 406 GLPGADGRAGVM-------------GPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGL 452 Query: 62 PLKPVPGGLAGAGLGAGLGAF--------PA--------VTFPGALVPGGVADAAAAYKA 105 P P G AG GL PA + FPG P G Sbjct: 453 PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTG----DPGKNG 508 Query: 106 AKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK-------VPGV-GLPGVY-PGGVL- 155 K AGL G G G + GA P GV+ GK PG GLPG P G + Sbjct: 509 DKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVG 568 Query: 156 -PGAR-FPGVGVLPGV--PTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP---- 207 PG R G LPG P G P G G I GP G P P G P Sbjct: 569 KPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVG 628 Query: 208 -IKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAA 263 + G GLP G +P G G G G G+ G P G G A A A Sbjct: 629 AVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAG 688 Query: 264 AKFGAGAAGVLPGVGGAGVPGVPGAIPGIG--GIAGVGTPAAAAAAAAA-----AKAAK- 315 A G AG G AG G PG +G G G PA AA A AK K Sbjct: 689 ATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKG 748 Query: 316 -------YGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPG 366 G P GP PG G G G P PG G P G G PG + G Sbjct: 749 ENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGP----PGMTGFPGAAGRTGPPGPS--G 802 Query: 367 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--------VGVGGIPGVA 418 + P A K G R G G T VGA G PGF G G PG Sbjct: 803 ISGPPGPPGPAGKEGLRGPRGDQGPVG-RTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP 861 Query: 419 GVPGVGGVPGVGGVPGV----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 474 G G+ G PG+ G+PG G+ A A PG PG +PGV AP Sbjct: 862 GPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921 Query: 475 GVGLA---PGVGVAPGVGVAPGV----GVAPGIGPGGVAAAAKSAAKV--AAKAQLRAAA 525 G PG PG PG G IGP G A A V A K R Sbjct: 922 GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGET 981 Query: 526 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 585 G +G G VG G +G G+ G PG P L K +PG+ G Sbjct: 982 G-PSGPVGPAGAVGPRG---PSGPQGIRGDKGEPGEKG-PRGLPGLKGHNGLQGLPGIAG 1036 Query: 586 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGG 643 G G G G GPA + A + G VG AG+ G G G PG G Sbjct: 1037 HHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPG 1096 Query: 644 LGGIPPAAAAKAAKYGAAG 662 G PP + +G G Sbjct: 1097 PPG-PPGVSGGGYDFGYDG 1114 Score = 83.2 bits (204), Expect = 8e-16 Identities = 98/316 (31%), Positives = 114/316 (36%), Gaps = 34/316 (10%) Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G G G PG G G G PG P AA+Y GVG+ PG G Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD-GKGVGLGPGPMGLMG 97 Query: 470 VGVAPGVGLAPGVGVAPGVGVAPG-------VGVAPGIGPGGVAAAAKSAAKVAAKAQLR 522 PG APG G PG G GP G A K + Sbjct: 98 PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERG 157 Query: 523 AAAGLGA----GIPGLG--VGV----GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA-- 570 GA G PGL G+ G+ GL G PG+ G PG PG A Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217 Query: 571 --AKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 627 + + GA P G G G++G VG G + AGP A + G G AG Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAG 277 Query: 628 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLS 687 G G +G+PG+ G G P GA GL G G AG L GVA PG Sbjct: 278 PAGPR-GEVGLPGLSGPVGPP-------GNPGANGLTGAKGAAG---LPGVAGAPGLPGP 326 Query: 688 PIFPGGACLGKACGRK 703 PG A G + Sbjct: 327 RGIPGPVGAAGATGAR 342 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 173 bits (439), Expect = 4e-43 Identities = 249/821 (30%), Positives = 304/821 (37%), Gaps = 157/821 (19%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPGP 651 Query: 122 GVSAGAVVPQPGAGVKPGKVPG----VGLPGV--------YPGGVLPGAR----FPGVGV 165 G + QPG PG PG VGLPG PG +PG++ PG+G Sbjct: 652 KGDPGQTITQPGKPGLPGN-PGRDGDVGLPGDPGLPGQPGLPG--IPGSKGEPGIPGIG- 707 Query: 166 LPGVPTGAGVK-----PKAPGVGGAFA--GIPGVGPFGGP--QPGVPLGYPIKAPKLPG- 215 LPG P G P APG G G PG F GP +PG L P P LPG Sbjct: 708 LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767 Query: 216 ----------GY----GLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAA 259 G+ G P TG LP G G G G G P G+G Q Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827 Query: 260 AKAAAKFGAGAAGVL-----PGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAA 311 G G+ PG G VPG PG PGI G G +G P + A Sbjct: 828 GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----------GVPGA----------G 350 + G + GP PG +G+PG +GVPG+ G+PG G Sbjct: 888 ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 351 IPVVPGA---------------GIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPGV---- 389 +P PG G+PG +PGV P+ + G +PG+ Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPG--IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 390 ---GVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG- 434 G G+P +G GFPG GV G PG +GVPG G PG+ G G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 435 ---VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 491 GIS + GL PG PG+ + G PG+ PG PG+ Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123 Query: 492 PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 551 PG PG P G++ + + G G PG G PG G G Sbjct: 1124 PGTPGPPG--PKGISGPPGNPGLPGEPGPV--GGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 552 LGVGAGVPGFGAV-PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVGA-GP 604 G PGFG P L K +PG+ G G G G PG GV G GP Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 605 AAAAAAAKAAAKA--------AQFGLVGAAGLGGL-GVGGL----GVPGVGGLGGIPPAA 651 + A K + GL G G GL G GG+ G PG GL G+P Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1299 Query: 652 AAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 G G G+ G G+ L G+ PG P FPG Sbjct: 1300 -------GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333 Score = 165 bits (418), Expect = 1e-40 Identities = 227/788 (28%), Positives = 285/788 (36%), Gaps = 174/788 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G GL P Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI---PGLPGDPG-- 319 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGL 146 +PG PG + K K G G PG+ V+P+PG G+ G+ +GL Sbjct: 320 YPGE--PGRDGE-----KGQKGDTGPPGPPGL---------VIPRPGTGITIGEKGNIGL 363 Query: 147 PGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 PG LPG + FPG+ PG+P G P F G G GP PG+ Sbjct: 364 PG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGI 416 Query: 203 PLGYPIKAPKLPGGYGLPYTTGKLPYGY-----------GPGGVAGAAGKAGYPTGTGVG 251 + P PG GLP G P G GP G G+ G G GV Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGV- 473 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 311 K F G+ G G+PG+PG +G G A A Sbjct: 474 ------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIPVVPGAGIPG 361 GA PG PGF PG G PG G+ G +G PGA G+P +PG PG Sbjct: 528 LPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT--PG 579 Query: 362 A-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----VGVGGIPG 416 +PG+ P+ + G G+ G+P +G G PGFG VG GI G Sbjct: 580 QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQG 638 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--------PGVGVAPGVGVAP 468 VAG PG G+PG G PG I+ + + G V PG PG+ + Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 469 GVGVAPGVGLA--------PGVGVAPGVGVAPG-VGVAPGIGPGGV-------------- 505 G PG+GL PG+ PG PG +G+ GP G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 506 -----------AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGLGVGVGVPGL 543 A K GL G PG G+PG+ Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 544 GVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 601 GV G PG+ G PG +PG G VPG G G+ G G PG + Sbjct: 819 GVQGPPGPPGIPGPIGQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 602 AG----PAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL-GVPGVGGLGGI-------- 647 G P A A+ K + G++G G G LG+ G GVPG+ G G+ Sbjct: 877 PGSPGLPGKAGASGFPGTKG-EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935 Query: 648 ---------------PPA--------AAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 PP + + + G G+ GV G G L G +PG Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 685 GLSPIFPG 692 P PG Sbjct: 996 SGQPGLPG 1003 Score = 163 bits (412), Expect = 6e-40 Identities = 223/728 (30%), Positives = 271/728 (37%), Gaps = 111/728 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----- 130 G PG +PG A+ + K G+ G PG G LG+ + VP Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 131 -----QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 184 QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 185 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 241 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 290 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 291 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 344 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 345 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP----- 395 G+PG PV G G PG P G + A + + G +PG G G P Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGL 1200 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 455 + G GG PG G G+PG G PG G PGV G PG P A + K Sbjct: 1201 SGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGPALEGPKGN-- 1253 Query: 456 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKS 511 PG PG PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1254 PGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGR 1313 Query: 512 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA 571 K G PGL G PG+ +GVPG G PG PG Sbjct: 1314 PGLNGMK-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1362 Query: 572 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG- 630 + + G G G G G+ G GP + GL G G GG Sbjct: 1363 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR 1422 Query: 631 LGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG-----------AGQFPLGGV 678 G GL G PG GL G PP G G V G A Q P G + Sbjct: 1423 KGDPGLPGQPGTRGLDG-PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTL 1481 Query: 679 AARPGFGL 686 GF L Sbjct: 1482 QVYEGFSL 1489 Score = 162 bits (409), Expect = 1e-39 Identities = 228/721 (31%), Positives = 274/721 (38%), Gaps = 143/721 (19%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPG--AIPGIGGIAGVGTPAAAAAAA 308 +K G G+ LPG G G PG+PG PG G G+ P Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP------- 738 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-------GIPG 361 PG PGF PG G PG +PG P G+P GA G PG Sbjct: 739 ---------------PGPPGF-PGPKGEPGFALPGPPGP-PGLPGFKGALGPKGDRGFPG 781 Query: 362 AAVP-------GVVSPEAAAKAAAKAAKYG--ARPGVGVGGIPTYGVGAGGFPG--FGVG 410 P G+ P+ + G PG+GV G P G G PG G Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP----GPPGIPGPIGQPG 837 Query: 411 VGGIPG-----------VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 459 + GIPG V G PG G PG+ G PG I P KA G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGF-PGTK 895 Query: 460 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAK 518 G+ PG PG PG PG+ G+ PG+ GP G +K + Sbjct: 896 GEMGMMGPPG---PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG-EKGSKGEPGLPGP 951 Query: 519 AQLRAAAGLGA----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 574 LG+ G PGL G+PG+ G GL G PG PG L Sbjct: 952 PGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGP 1007 Query: 575 KYGAAVPGVLG-----GL-GALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGA 625 K +PG G GL G +G +G PG GV G GP+ + Q G G Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067 Query: 626 AGLGGLGVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 G+ +G+ GL G G GL G P P G GL G G GQ L G P Sbjct: 1068 PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP 1127 Query: 683 G 683 G Sbjct: 1128 G 1128 Score = 158 bits (400), Expect = 1e-38 Identities = 225/735 (30%), Positives = 277/735 (37%), Gaps = 114/735 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA--PGVGVAP 468 G PG G PG G+ G+ G G + P Q +PG+GV PG P Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPG----LPGIGVQGPPGPPGIP 830 Query: 469 GVGVAPGVGLAPG-----------VGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 516 G PG+ PG V PG +PG+ APG IGP G + A + Sbjct: 831 GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGAS 889 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 + G+ G PG +G+PG +GVPGL G+ G +PG K +K Sbjct: 890 GFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP-TGEKGSKG 944 Query: 577 GAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 628 +PG +LG G G G+PG +GP K Q GL G G Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ-GLPGDPGQ 992 Query: 629 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 688 GL G G+PG G G P + G GL G +G G GV PG P Sbjct: 993 PGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050 Query: 689 IFPGGACLGKACGRK 703 PG L G K Sbjct: 1051 GQPGSPGLPGQKGDK 1065 Score = 129 bits (323), Expect = 1e-29 Identities = 207/730 (28%), Positives = 253/730 (34%), Gaps = 150/730 (20%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAP 462 G+ + G PG+ G PG G+PG G G I P + G G+ Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 463 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 522 GV G + G+ PG PG+ PG PG + + K +A Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPG---QPGLPGLPG-PPGSLGFPGQKGEK--GQAGAT 523 Query: 523 AAAGLGAGIPGLGVGVGVPG--------------------LGVGAGVPGLGVGAGVPGFG 562 GL GIPG G PG LG G PGL G PG Sbjct: 524 GPKGL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELG-SPGAPGLPGLPGTPGQD 581 Query: 563 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 622 +PG L K G G G G G G+PG + GP G Sbjct: 582 GLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP----------GP 630 Query: 623 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 VG G+ G+ G G PG+ G G P + K G G G G G G+ +P Sbjct: 631 VGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 683 GFGLSPIFPG 692 G P PG Sbjct: 690 GL---PGIPG 696 Score = 73.6 bits (179), Expect = 6e-13 Identities = 118/410 (28%), Positives = 141/410 (34%), Gaps = 73/410 (17%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 470 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 522 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 523 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 577 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 638 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLS 687 PG+ GL G P + + G G G G G P G V RPG G++ Sbjct: 308 QPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRPGTGIT 354 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 172 bits (437), Expect = 7e-43 Identities = 247/818 (30%), Positives = 300/818 (36%), Gaps = 148/818 (18%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPGP 651 Query: 122 GVSAGAVVPQPGAGVKPGKVPG----VGLPGV--------YPGGVLPGAR----FPGVGV 165 G + QPG PG PG VGLPG PG +PG++ PG+G Sbjct: 652 KGDPGQTITQPGKPGLPGN-PGRDGDVGLPGDPGLPGQPGLPG--IPGSKGEPGIPGIG- 707 Query: 166 LPGVPTGAGVK-----PKAPGVGGAFA--GIPGVGPFGGP--QPGVPLGYPIKAPKLPG- 215 LPG P G P APG G G PG F GP +PG L P P LPG Sbjct: 708 LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767 Query: 216 ----------GY----GLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAA 259 G+ G P TG LP G G G G G P G+G Q Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827 Query: 260 AKAAAKFGAGAAGVL-----PGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAA 311 G G+ PG G VPG PG PGI G G +G P + A Sbjct: 828 GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----------GVPGA----------G 350 + G + GP PG +G+PG +GVPG+ G+PG G Sbjct: 888 ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 351 IPVVPGA---------------GIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPGV---- 389 +P PG G+PG +PGV P+ + G +PG+ Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPG--IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 390 ---GVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG- 434 G G+P +G GFPG GV G PG +GVPG G PG+ G G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 435 ---VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 491 GIS + GL PG PG+ + G PG+ PG PG+ Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123 Query: 492 PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 551 PG PG P G++ + + G G PG G PG G G Sbjct: 1124 PGTPGPPG--PKGISGPPGNPGLPGEPGPV--GGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 552 LGVGAGVPGFGAV-PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVGA-GP 604 G PGFG P L K +PG+ G G G G PG GV G GP Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 605 AAAAAAAKAAAKA--AQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--------PAAAAK 654 + A K G G G GL G G PG+ G GGI P Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLP-GPEGPPGLPGNGGIKGEKGNPGQPGLPGL 1298 Query: 655 AAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 G G G+ G G+ L G+ PG P FPG Sbjct: 1299 PGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1336 Score = 165 bits (418), Expect = 1e-40 Identities = 227/788 (28%), Positives = 285/788 (36%), Gaps = 174/788 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G GL P Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI---PGLPGDPG-- 319 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGL 146 +PG PG + K K G G PG+ V+P+PG G+ G+ +GL Sbjct: 320 YPGE--PGRDGE-----KGQKGDTGPPGPPGL---------VIPRPGTGITIGEKGNIGL 363 Query: 147 PGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 PG LPG + FPG+ PG+P G P F G G GP PG+ Sbjct: 364 PG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGI 416 Query: 203 PLGYPIKAPKLPGGYGLPYTTGKLPYGY-----------GPGGVAGAAGKAGYPTGTGVG 251 + P PG GLP G P G GP G G+ G G GV Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGV- 473 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 311 K F G+ G G+PG+PG +G G A A Sbjct: 474 ------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIPVVPGAGIPG 361 GA PG PGF PG G PG G+ G +G PGA G+P +PG PG Sbjct: 528 LPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT--PG 579 Query: 362 A-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----VGVGGIPG 416 +PG+ P+ + G G+ G+P +G G PGFG VG GI G Sbjct: 580 QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQG 638 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--------PGVGVAPGVGVAP 468 VAG PG G+PG G PG I+ + + G V PG PG+ + Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 469 GVGVAPGVGLA--------PGVGVAPGVGVAPG-VGVAPGIGPGGV-------------- 505 G PG+GL PG+ PG PG +G+ GP G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 506 -----------AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGLGVGVGVPGL 543 A K GL G PG G+PG+ Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 544 GVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 601 GV G PG+ G PG +PG G VPG G G+ G G PG + Sbjct: 819 GVQGPPGPPGIPGPIGQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 602 AG----PAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL-GVPGVGGLGGI-------- 647 G P A A+ K + G++G G G LG+ G GVPG+ G G+ Sbjct: 877 PGSPGLPGKAGASGFPGTKG-EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935 Query: 648 ---------------PPA--------AAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 PP + + + G G+ GV G G L G +PG Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 685 GLSPIFPG 692 P PG Sbjct: 996 SGQPGLPG 1003 Score = 162 bits (409), Expect = 1e-39 Identities = 228/721 (31%), Positives = 274/721 (38%), Gaps = 143/721 (19%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPG--AIPGIGGIAGVGTPAAAAAAA 308 +K G G+ LPG G G PG+PG PG G G+ P Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP------- 738 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-------GIPG 361 PG PGF PG G PG +PG P G+P GA G PG Sbjct: 739 ---------------PGPPGF-PGPKGEPGFALPGPPGP-PGLPGFKGALGPKGDRGFPG 781 Query: 362 AAVP-------GVVSPEAAAKAAAKAAKYG--ARPGVGVGGIPTYGVGAGGFPG--FGVG 410 P G+ P+ + G PG+GV G P G G PG G Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP----GPPGIPGPIGQPG 837 Query: 411 VGGIPG-----------VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 459 + GIPG V G PG G PG+ G PG I P KA G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGF-PGTK 895 Query: 460 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAK 518 G+ PG PG PG PG+ G+ PG+ GP G +K + Sbjct: 896 GEMGMMGPPG---PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG-EKGSKGEPGLPGP 951 Query: 519 AQLRAAAGLGA----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 574 LG+ G PGL G+PG+ G GL G PG PG L Sbjct: 952 PGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGP 1007 Query: 575 KYGAAVPGVLG-----GL-GALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGA 625 K +PG G GL G +G +G PG GV G GP+ + Q G G Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067 Query: 626 AGLGGLGVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 G+ +G+ GL G G GL G P P G GL G G GQ L G P Sbjct: 1068 PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP 1127 Query: 683 G 683 G Sbjct: 1128 G 1128 Score = 162 bits (409), Expect = 1e-39 Identities = 223/729 (30%), Positives = 271/729 (37%), Gaps = 110/729 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----- 130 G PG +PG A+ + K G+ G PG G LG+ + VP Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 131 -----QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 184 QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 185 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 241 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 290 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 291 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 344 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 345 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP----- 395 G+PG PV G G PG P G + A + + G +PG G G P Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGL 1200 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 455 + G GG PG G G+PG G PG G PGV G PG P A + K Sbjct: 1201 SGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGPALEGPKGNPG 1255 Query: 456 P-GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAK 510 P G PG PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1256 PQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1315 Query: 511 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 570 K G PGL G PG+ +GVPG G PG PG Sbjct: 1316 RPGLNGMK-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364 Query: 571 AKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 630 + + G G G G G+ G GP + GL G G GG Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424 Query: 631 -LGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG-----------AGQFPLGG 677 G GL G PG GL G PP G G V G A Q P G Sbjct: 1425 RKGDPGLPGQPGTRGLDG-PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1483 Query: 678 VAARPGFGL 686 + GF L Sbjct: 1484 LQVYEGFSL 1492 Score = 158 bits (400), Expect = 1e-38 Identities = 225/735 (30%), Positives = 277/735 (37%), Gaps = 114/735 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA--PGVGVAP 468 G PG G PG G+ G+ G G + P Q +PG+GV PG P Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPG----LPGIGVQGPPGPPGIP 830 Query: 469 GVGVAPGVGLAPG-----------VGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 516 G PG+ PG V PG +PG+ APG IGP G + A + Sbjct: 831 GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGAS 889 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 + G+ G PG +G+PG +GVPGL G+ G +PG K +K Sbjct: 890 GFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP-TGEKGSKG 944 Query: 577 GAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 628 +PG +LG G G G+PG +GP K Q GL G G Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ-GLPGDPGQ 992 Query: 629 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 688 GL G G+PG G G P + G GL G +G G GV PG P Sbjct: 993 PGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050 Query: 689 IFPGGACLGKACGRK 703 PG L G K Sbjct: 1051 GQPGSPGLPGQKGDK 1065 Score = 129 bits (323), Expect = 1e-29 Identities = 207/730 (28%), Positives = 253/730 (34%), Gaps = 150/730 (20%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAP 462 G+ + G PG+ G PG G+PG G G I P + G G+ Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 463 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 522 GV G + G+ PG PG+ PG PG + + K +A Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPG---QPGLPGLPG-PPGSLGFPGQKGEK--GQAGAT 523 Query: 523 AAAGLGAGIPGLGVGVGVPG--------------------LGVGAGVPGLGVGAGVPGFG 562 GL GIPG G PG LG G PGL G PG Sbjct: 524 GPKGL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELG-SPGAPGLPGLPGTPGQD 581 Query: 563 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 622 +PG L K G G G G G G+PG + GP G Sbjct: 582 GLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP----------GP 630 Query: 623 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 VG G+ G+ G G PG+ G G P + K G G G G G G+ +P Sbjct: 631 VGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 683 GFGLSPIFPG 692 G P PG Sbjct: 690 GL---PGIPG 696 Score = 73.6 bits (179), Expect = 6e-13 Identities = 118/410 (28%), Positives = 141/410 (34%), Gaps = 73/410 (17%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 470 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 522 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 523 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 577 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 638 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLS 687 PG+ GL G P + + G G G G G P G V RPG G++ Sbjct: 308 QPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRPGTGIT 354 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 172 bits (435), Expect = 1e-42 Identities = 230/734 (31%), Positives = 265/734 (36%), Gaps = 123/734 (16%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPG-------AGLGALGG-----------GALGPGGKP 62 P G PG PG GV G YPG AG + G G +GP G P Sbjct: 271 PQGARGFPGT-PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329 Query: 63 ---LKPVPGGLAG----------AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG 109 + P G AG AG +G FPGA PG +A G Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA--PGAKGEAGPTGARGPEG 387 Query: 110 A-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPG 168 A G G PG G AGA PG PG G PG+ PG R P Sbjct: 388 AQGPRGEPGTPGSPGPAGA-SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446 Query: 169 VPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK--LPGGYGLPYTTGKL 226 P G + PG+ G F G GP G P P P G P A + G G P G + Sbjct: 447 GPLGPKGQTGEPGIAG-FKG--EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503 Query: 227 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 GP G GA G G+P G+ GP+ A +G AG G G PG Sbjct: 504 ----GPPGERGAPGNRGFPGQDGLAGPKGAPGERGP------SGLAGPKGANGDPGRPGE 553 Query: 286 PGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----G 340 PG +PG G+ G G + + G P G PGV+G PG G Sbjct: 554 PG-LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 612 Query: 341 VPGVGVPGAGIPVVPG-AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 398 PG G+P PG G+PG G P A A + + GA G G+P Sbjct: 613 EPG-KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP--- 668 Query: 399 VGAGGFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP 456 G G PG G G G+PG AG PG+ G G G PG SP AQ + +P Sbjct: 669 -GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-----LP 722 Query: 457 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV---------------------- 494 G G A G PG PG+ PG A G+ Sbjct: 723 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782 Query: 495 ---GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 551 G+ IGP G A A +V +A GA PG G PG Sbjct: 783 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA-----------PGERGETGPPG 831 Query: 552 LGVGAGVPGFGAVPGALAAAKAA--KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 609 AG PG PGA A K A PG G GA G G P GV G A A Sbjct: 832 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG-PTGVTGPKGARGAQ 890 Query: 610 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG 669 A G GAAG G G G PG G PP + K GA G G G Sbjct: 891 GPPGAT-----GFPGAAGRVG-PPGSNGNPGPPG----PPGPSGKDGPKGARGDSGPPGR 940 Query: 670 AGQFPLGGVAARPG 683 AG+ L G A PG Sbjct: 941 AGEPGLQGPAGPPG 954 Score = 167 bits (422), Expect = 4e-41 Identities = 225/705 (31%), Positives = 256/705 (36%), Gaps = 98/705 (13%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGV 123 P A FPG P G A K G+ G G G Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 471 Query: 124 SAGAVVPQ--PGAGVKPGKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKA 179 G PQ PG + GK G P GV P G PG R PG PG AG K A Sbjct: 472 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPK-GA 529 Query: 180 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAG 237 PG G +G+ G G PG P P LPG GL G P G GP G G Sbjct: 530 PGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 582 Query: 238 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGI 295 G+ G P GPQ A GA G G G+PG PG +PG G Sbjct: 583 EDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPV 353 G P A A + + GA PG GF PG G PG G G PG Sbjct: 638 TGAAGP--PGPAGPAGERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG----- 681 Query: 354 VPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G+PG A PG+V P + GA+ G G+P G P G Sbjct: 682 --DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPA 737 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGVAPGV 464 G PG G PG+ G+PG G G+ + + A K GL +G PG Sbjct: 738 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGP 796 Query: 465 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRA 523 A G G PG + G APG G GP G A + + AK + Sbjct: 797 AGANGEKGEVG---PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 853 Query: 524 AAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 582 A G AG PG G PG GV G G G PGA PG Sbjct: 854 AGQKGDAGAPGPQGPSGAPGPQGPTGVTG---PKGARGAQGPPGA----------TGFPG 900 Query: 583 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPG 640 G +G G G PG GP+ A + G G GL G G G PG Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 960 Query: 641 VGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G PP A + G GL G G G L G + PG Sbjct: 961 DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 1005 Score = 163 bits (412), Expect = 6e-40 Identities = 243/766 (31%), Positives = 271/766 (35%), Gaps = 178/766 (23%) Query: 54 GALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GALVPGGVADA 99 G GP G P P P GL G AG GA LG P G P G A A Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGPAGA 217 Query: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVL 155 + + G G PGV G G PG KPG G PG P G Sbjct: 218 PGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272 Query: 156 PGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-------GPFGGPQPGVPLGY 206 FPG LPGV G PG+ GA AG PGV G G P P P G Sbjct: 273 GARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 328 Query: 207 PIKAPKL--------------PGGYGLPYTTGKLPYGYGPG--GVAGAAGKAGYPTGTGV 250 P + + PG G P G P G GPG G GA G+AG PTG Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVG--PAG-GPGFPGAPGAKGEAG-PTGAR- 383 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--------LPGV-GGAGVPGVPGA------------- 288 GP+ A + G AG +PG G AG PG+ GA Sbjct: 384 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443 Query: 289 -------------IPGIGGIAG----------VGTPAAAAAAAAAAKAAKYGAAAGLVPG 325 PGI G G G A A K G G+ P Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503 Query: 326 GPGFGPGVVGVPG-AGVPG-------VGVPGA-------------GIPVVPG-AGIPGA- 362 GP PG G PG G PG G PG G P PG G+PGA Sbjct: 504 GP---PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 363 ---AVPGVVSPEAAAKAAAKAAKYGARPG----VGVGGIPTYGVGAGGFPGFGVGVGGIP 415 PG P+ + + G RPG G G P G GFPG G G P Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDG-RPGPPGPQGARGQP----GVMGFPG-PKGANGEP 614 Query: 416 GVAGVPGVGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 470 G AG G+ G PG+ G+PG P A A + + G APG G+ Sbjct: 615 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG-------APGPSGFQGL 667 Query: 471 GVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 529 PG PG G PG PG APG +GP G A+ L+ GL Sbjct: 668 PGPPG---PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG-LQGPRGL-P 722 Query: 530 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP-GVLGGLG 588 G PG G G AG PG G PG +PG AA G A P G G +G Sbjct: 723 GTPGTD---GPKGASGPAGPPG---AQGPPGLQGMPGERGAA-----GIAGPKGDRGDVG 771 Query: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 648 G G PG G G A + G VG G G G G PG G G P Sbjct: 772 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG-SAGARGAPGERGETG-P 829 Query: 649 PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 P A A GA G G G G+ G A PG P P GA Sbjct: 830 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG----PQGPSGA 871 Score = 154 bits (389), Expect = 3e-37 Identities = 235/709 (33%), Positives = 263/709 (37%), Gaps = 110/709 (15%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 550 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 PGA + G DA K +GA G G PG G + G QPG PG Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG----QPGVMGFPG 606 Query: 140 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPF 195 G PG LPGA PG+ LPG TGA P G G G PG F Sbjct: 607 PKGANGEPGKAGEKGLPGA--PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664 Query: 196 GGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQA 254 G PG P G P + K PG G+P G P GP G G G+ G P G+ GP+ Sbjct: 665 QG-LPGPP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQGLQGPRG 720 Query: 255 AAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAAAAAAAA 309 K +G AG PG G G+PG GA GI G G G A Sbjct: 721 LPGTPGTDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGEKGPEGA 778 Query: 310 AAKAAKYGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG-AGIPVV 354 K G + P GP PG G GA G PG G PG AG Sbjct: 779 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838 Query: 355 PGA-GIPG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 PGA G PG A PG P A G + G G P G Sbjct: 839 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----G 894 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-----V 455 A GFPG G G PG G PG G PG G G + +A + GL Sbjct: 895 ATGFPG-AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGLQGPAGP 952 Query: 456 PGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK 514 PG PG G PG GLA G+ G+ G PG+ PG K A Sbjct: 953 PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEPGKQGAP 1010 Query: 515 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 574 A+ + G PG VG PGL AG PG G PG PG AA Sbjct: 1011 GASGDR---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRDGAA--- 1052 Query: 575 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 634 GV G G G VG PG GP + A K G GA G G G Sbjct: 1053 -------GVKGDRGETGAVGAPG---APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS-G 1101 Query: 635 GLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G+ G G P +A + G GL G G G L G+ PG Sbjct: 1102 PAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTG---LQGLPGPPG 1146 Score = 143 bits (361), Expect = 5e-34 Identities = 226/731 (30%), Positives = 261/731 (35%), Gaps = 113/731 (15%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLGA 77 P G PG PG G+PG G A G +GP G P +P P G GA Sbjct: 541 PKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP 599 Query: 78 GLGAFPAVT-------------FPGAL----VPGGVADAAAAYKAAKAGA----GLGGVP 116 G+ FP PGA +PG + AA AG G G P Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659 Query: 117 GVGGLGVSAGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-FPGV 163 G G G P PG G KPG VPG G PG+ +PG PGA+ G Sbjct: 660 GPSGFQGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718 Query: 164 GVLPGVPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGYPIK 209 LPG P G K + PG G G+PG GP G + V P Sbjct: 719 RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKGPEG 777 Query: 210 APKLPGGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAA 260 AP GG GL G P G GP G AG+AG G P G GP A A Sbjct: 778 APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG 837 Query: 261 KAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAK 315 A GA G G G G PG PG G GV P A A A Sbjct: 838 PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 897 Query: 316 YGAAAGLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPGA-A 363 + AAG V P G PG G PG G G G PG AG P + G AG PG Sbjct: 898 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957 Query: 364 VPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 PG P A G R G+ G+P G GFPG +PG +G PG Sbjct: 958 EPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGEPGK 1006 Query: 424 GGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 481 G PG G G + P A + + G +PG PG A GV G Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKGDRG 1059 Query: 482 VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGV 540 A G APG +PG P G + A+ + + GA GI G G Sbjct: 1060 ETGAVGAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117 Query: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGALGG 592 G G GL G G +PG A+ A G PG +G G G Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1177 Query: 593 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 652 GIPG + GP + A G G G G G+ G+G P Sbjct: 1178 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQ 1237 Query: 653 AKAAKYGAAGL 663 A A GL Sbjct: 1238 YMRADQAAGGL 1248 Score = 134 bits (337), Expect = 3e-31 Identities = 212/676 (31%), Positives = 238/676 (35%), Gaps = 100/676 (14%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 118 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 163 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 PG P G + A AG G G LGV G + P G PG Sbjct: 164 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRG-PPGPAGAP 218 Query: 145 GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPL 204 G G PG PGV G P G P PG G AG PG GP PG Sbjct: 219 GPQGFQGNPGEPGE--PGVSGPMG-PRGPPGPPGKPGDDGE-AGKPGKAGERGP-PG--- 270 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAA 264 P A PG GLP G Y G+ GA G+AG P GV ++ + Sbjct: 271 --PQGARGFPGTPGLPGVKGHRGYP----GLDGAKGEAGAP---GVKGESGS-------- 313 Query: 265 KFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVP 324 PG G+ P P +PG G G A AA A + G A P Sbjct: 314 ----------PGENGSPGPMGPRGLPGERGRTG-----PAGAAGARGNDGQPGPAGPPGP 358 Query: 325 GGPGFGPGVVGVPG----AGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAK 379 GP GPG G PG AG G G GA P G PG PG P A+ Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP----RGEPG--TPGSPGPAGASGNPGT 412 Query: 380 AAKYGARPGVGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 GA+ G GI GA GFPG G G G G G G PG+ G G Sbjct: 413 DGIPGAKGSAGAPGI----AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ- 467 Query: 438 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV--APGVGLAPGVGVAPGVGVAPGVG 495 P+ + A G G G GVG PG APG PG G Sbjct: 468 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 527 Query: 496 VAPG-IGPGGVAA--AAKSAAKVAAKAQLRAAAGL-----GAGIPGLGVGVGVPGLGVGA 547 APG GP G+A A + L A GL AG G G PG Sbjct: 528 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 587 Query: 548 GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAA 607 G PG G PG PG K A G G GA G G+PG G A Sbjct: 588 GPPGPQGARGQPGVMGFPG----PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 643 Query: 608 AAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVL 667 A A + + G G +G GL G PG G GG P G AG G++ Sbjct: 644 PGPAGPAGERGEQGAPGPSGFQGLP----GPPGPPGEGGKPGDQGVP----GEAGAPGLV 695 Query: 668 GGAGQFPLGGVAARPG 683 G G+ G PG Sbjct: 696 GPRGERGFPGERGSPG 711 Score = 130 bits (326), Expect = 5e-30 Identities = 189/599 (31%), Positives = 213/599 (35%), Gaps = 86/599 (14%) Query: 167 PGVPTGAGVKPKAPGVGGAFAGIPG-----VGPFGGPQPGVPLGY--PIKAPKLPGGYGL 219 P PT PG G G PG VGP G P P P G P G G Sbjct: 87 PICPTDLATASGQPGPKGQ-KGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA 145 Query: 220 PYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL----- 274 P G+ PG G G G P G+G AA A K G GV+ Sbjct: 146 PGPRGRDGEPGTPGN-PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204 Query: 275 -------PGVGGA-------GVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 319 PG GA G PG PG PG+ G G G P +A K G A Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGE-PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263 Query: 320 AGLVPGGP----GFGPGVVGVPGA----GVPGV-GVPG-AGIPVVPG-AGIPGA-AVPGV 367 P GP GF PG G+PG G PG+ G G AG P V G +G PG PG Sbjct: 264 GERGPPGPQGARGF-PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 322 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYG-----VGAGGFPGF--GVGVGGIPGVAGV 420 + P + GA G G P VG G PGF G G G G Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 382 Query: 421 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL--VPGVGVAPGVGVAPGVGVAPGVGL 478 G G G G PG SP A A+ G+ G APG+ APG PG Sbjct: 383 RGPEGAQGPRGEPGTPGSP-GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF---PGPRG 438 Query: 479 APGVGVAPGVGVAPGVGVAPGI-------GPGGVAAAA--KSAAKVAAKAQLRAAAGLGA 529 PG A G G PGI GP G A + A A + R A G Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498 Query: 530 GIPGLGVGV--GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 587 G+ +G G PG G GL G PG P LA K A PG G Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG-PSGLAGPKGANGDPGRPGEPGLP 557 Query: 588 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--------------GV 633 GA G G PG G + A + G GA G G+ Sbjct: 558 GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA 617 Query: 634 GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 G G+PG GL G+P K + GAAG G G AG+ G GF P PG Sbjct: 618 GEKGLPGAPGLRGLP----GKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPG 672 Score = 123 bits (309), Expect = 5e-28 Identities = 161/510 (31%), Positives = 183/510 (35%), Gaps = 55/510 (10%) Query: 210 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY------PTGTGVGPQAAAAAAAKAA 263 +P++P G P L G G G G+ G P G GPQ A Sbjct: 77 SPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPP-GPQGPAGEQGPRG 135 Query: 264 AKFGAGAAGVLPGVGGA----GVPGVPG--AIPGIGGIAGVGTPAAAAAAAA---AAKAA 314 + G G PG G G PG PG PG G G+G AA A A A Sbjct: 136 DRGDKGEKGA-PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 194 Query: 315 KYGAAAG-LVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVV 368 + G G + P GP PG G PG G PG G PG P+ P G PG PG Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGKP 251 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 + A KA + G G G P G G PG G G PG+ G G G PG Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFP----GTPGLPGV-KGHRGYPGLDGAKGEAGAPG 306 Query: 429 V---GGVPGVGISPEAQAAAAAKAAKYGLVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVG 483 V G PG SP + P G A G PG PG VG A G G Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366 Query: 484 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 542 G G GP G + A+ G GIPG G PG Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426 Query: 543 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVV 600 + AG PG G PG G L K PG+ G G G G PG G Sbjct: 427 I---AGAPGFPGPRGPPGPQGATGPL----GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479 Query: 601 GA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYG 659 GA GPA A + G +G G G G G PG GL G P A + G Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERG-APGNRGFPGQDGLAG-PKGAPGERGPSG 537 Query: 660 AAGLGGVLGGAGQ-----FP-LGGVAARPG 683 AG G G G+ P G+ RPG Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARGLTGRPG 567 Score = 123 bits (309), Expect = 5e-28 Identities = 161/520 (30%), Positives = 181/520 (34%), Gaps = 51/520 (9%) Query: 194 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 253 PFG P P + + PG G G + GP G G G AG GP+ Sbjct: 81 PFGECCPICPTDLATASGQ-PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQ-----GPR 134 Query: 254 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKA 313 + A G G G G PG PG PG G+ G A A Sbjct: 135 GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGG 193 Query: 314 AKYGAAAG-LVPGGPGFGPGVVGVPGA----GVPGV-GVPGAGIPVVPGAGIPGAAVPGV 367 A+ G G + P GP PG G PG G PG G PG P+ P G PG PG Sbjct: 194 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGK 250 Query: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 427 + A KA + G G G P G G PG G G PG+ G G G P Sbjct: 251 PGDDGEAGKPGKAGERGPPGPQGARGFP----GTPGLPGVK-GHRGYPGLDGAKGEAGAP 305 Query: 428 GV---GGVPGVGISPEAQAAAAAKAAKYGLVP-GVGVAPGVGVAPGVGVAPG-VGLAPGV 482 GV G PG SP + P G A G PG PG VG A G Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365 Query: 483 GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVP 541 G G G GP G + A+ G GIPG G P Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAP 425 Query: 542 GLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 601 G+ AG PG G PG G L K PG+ G G G G PG Sbjct: 426 GI---AGAPGFPGPRGPPGPQGATGPLGP----KGQTGEPGIAGFKGEQGPKGEPGP--- 475 Query: 602 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAA 661 AGP A A K GA G G GVG +G PG G G G Sbjct: 476 AGPQGAPGPAGEEGKR------GARGEPG-GVGPIGPPGERGAPG-------NRGFPGQD 521 Query: 662 GLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACG 701 GL G G G+ G+A G P PG L A G Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 561 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 172 bits (435), Expect = 1e-42 Identities = 230/734 (31%), Positives = 265/734 (36%), Gaps = 123/734 (16%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPG-------AGLGALGG-----------GALGPGGKP 62 P G PG PG GV G YPG AG + G G +GP G P Sbjct: 202 PQGARGFPGT-PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 260 Query: 63 ---LKPVPGGLAG----------AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG 109 + P G AG AG +G FPGA PG +A G Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA--PGAKGEAGPTGARGPEG 318 Query: 110 A-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPG 168 A G G PG G AGA PG PG G PG+ PG R P Sbjct: 319 AQGPRGEPGTPGSPGPAGA-SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 169 VPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK--LPGGYGLPYTTGKL 226 P G + PG+ G F G GP G P P P G P A + G G P G + Sbjct: 378 GPLGPKGQTGEPGIAG-FKG--EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434 Query: 227 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 GP G GA G G+P G+ GP+ A +G AG G G PG Sbjct: 435 ----GPPGERGAPGNRGFPGQDGLAGPKGAPGERGP------SGLAGPKGANGDPGRPGE 484 Query: 286 PGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----G 340 PG +PG G+ G G + + G P G PGV+G PG G Sbjct: 485 PG-LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543 Query: 341 VPGVGVPGAGIPVVPG-AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 398 PG G+P PG G+PG G P A A + + GA G G+P Sbjct: 544 EPG-KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP--- 599 Query: 399 VGAGGFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP 456 G G PG G G G+PG AG PG+ G G G PG SP AQ + +P Sbjct: 600 -GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG-----LP 653 Query: 457 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV---------------------- 494 G G A G PG PG+ PG A G+ Sbjct: 654 GTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 713 Query: 495 ---GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 551 G+ IGP G A A +V +A GA PG G PG Sbjct: 714 GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGA-----------PGERGETGPPG 762 Query: 552 LGVGAGVPGFGAVPGALAAAKAA--KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 609 AG PG PGA A K A PG G GA G G P GV G A A Sbjct: 763 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG-PTGVTGPKGARGAQ 821 Query: 610 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG 669 A G GAAG G G G PG G PP + K GA G G G Sbjct: 822 GPPGAT-----GFPGAAGRVG-PPGSNGNPGPPG----PPGPSGKDGPKGARGDSGPPGR 871 Query: 670 AGQFPLGGVAARPG 683 AG+ L G A PG Sbjct: 872 AGEPGLQGPAGPPG 885 Score = 167 bits (422), Expect = 4e-41 Identities = 225/705 (31%), Positives = 256/705 (36%), Gaps = 98/705 (13%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAY--KAAKAGAGLGGVPGVGGLGV 123 P A FPG P G A K G+ G G G Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKG 402 Query: 124 SAGAVVPQ--PGAGVKPGKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKA 179 G PQ PG + GK G P GV P G PG R PG PG AG K A Sbjct: 403 EPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGPK-GA 460 Query: 180 PGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPGGVAG 237 PG G +G+ G G PG P P LPG GL G P G GP G G Sbjct: 461 PGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPSGAPG 513 Query: 238 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGI 295 G+ G P GPQ A GA G G G+PG PG +PG G Sbjct: 514 EDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568 Query: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGAGIPV 353 G P A A + + GA PG GF PG G PG G G PG Sbjct: 569 TGAAGP--PGPAGPAGERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG----- 612 Query: 354 VPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG 412 G+PG A PG+V P + GA+ G G+P G P G Sbjct: 613 --DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGASGPA 668 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGVAPGV 464 G PG G PG+ G+PG G G+ + + A K GL +G PG Sbjct: 669 GPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG-PPGP 727 Query: 465 GVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRA 523 A G G PG + G APG G GP G A + + AK + Sbjct: 728 AGANGEKGEVG---PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGE 784 Query: 524 AAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPG 582 A G AG PG G PG GV G G G PGA PG Sbjct: 785 AGQKGDAGAPGPQGPSGAPGPQGPTGVTG---PKGARGAQGPPGA----------TGFPG 831 Query: 583 VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPG 640 G +G G G PG GP+ A + G G GL G G G PG Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 891 Query: 641 VGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G PP A + G GL G G G L G + PG Sbjct: 892 DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 936 Score = 163 bits (412), Expect = 6e-40 Identities = 243/766 (31%), Positives = 271/766 (35%), Gaps = 178/766 (23%) Query: 54 GALGPGGKPLKPVPGGLAG-------------AGLGAGLGAFPAVTFP-GALVPGGVADA 99 G GP G P P P GL G AG GA LG P G P G A A Sbjct: 90 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG-GAQLGVMQGPMGPMGPRGPPGPAGA 148 Query: 100 AAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVL 155 + + G G PGV G G PG KPG G PG P G Sbjct: 149 PGP-QGFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203 Query: 156 PGARFPGVGVLPGVPTGAGVKPKAPGVGGA--FAGIPGV-------GPFGGPQPGVPLGY 206 FPG LPGV G PG+ GA AG PGV G G P P P G Sbjct: 204 GARGFPGTPGLPGVKGHRGY----PGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL 259 Query: 207 PIKAPKL--------------PGGYGLPYTTGKLPYGYGPG--GVAGAAGKAGYPTGTGV 250 P + + PG G P G P G GPG G GA G+AG PTG Sbjct: 260 PGERGRTGPAGAAGARGNDGQPGPAGPPGPVG--PAG-GPGFPGAPGAKGEAG-PTGAR- 314 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--------LPGV-GGAGVPGVPGA------------- 288 GP+ A + G AG +PG G AG PG+ GA Sbjct: 315 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 374 Query: 289 -------------IPGIGGIAG----------VGTPAAAAAAAAAAKAAKYGAAAGLVPG 325 PGI G G G A A K G G+ P Sbjct: 375 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434 Query: 326 GPGFGPGVVGVPG-AGVPG-------VGVPGA-------------GIPVVPG-AGIPGA- 362 GP PG G PG G PG G PG G P PG G+PGA Sbjct: 435 GP---PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491 Query: 363 ---AVPGVVSPEAAAKAAAKAAKYGARPG----VGVGGIPTYGVGAGGFPGFGVGVGGIP 415 PG P+ + + G RPG G G P G GFPG G G P Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDG-RPGPPGPQGARGQP----GVMGFPG-PKGANGEP 545 Query: 416 GVAGVPGVGGVPGVGGVPGV-----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 470 G AG G+ G PG+ G+PG P A A + + G APG G+ Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQG-------APGPSGFQGL 598 Query: 471 GVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 529 PG PG G PG PG APG +GP G A+ L+ GL Sbjct: 599 PGPPG---PPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG-LQGPRGL-P 653 Query: 530 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP-GVLGGLG 588 G PG G G AG PG G PG +PG AA G A P G G +G Sbjct: 654 GTPGTD---GPKGASGPAGPPG---AQGPPGLQGMPGERGAA-----GIAGPKGDRGDVG 702 Query: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 648 G G PG G G A + G VG G G G G PG G G P Sbjct: 703 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG-SAGARGAPGERGETG-P 760 Query: 649 PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 P A A GA G G G G+ G A PG P P GA Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG----PQGPSGA 802 Score = 154 bits (389), Expect = 3e-37 Identities = 235/709 (33%), Positives = 263/709 (37%), Gaps = 110/709 (15%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 481 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 PGA + G DA K +GA G G PG G + G QPG PG Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARG----QPGVMGFPG 537 Query: 140 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GIPGVGPF 195 G PG LPGA PG+ LPG TGA P G G G PG F Sbjct: 538 PKGANGEPGKAGEKGLPGA--PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595 Query: 196 GGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQA 254 G PG P G P + K PG G+P G P GP G G G+ G P G+ GP+ Sbjct: 596 QG-LPGPP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQGLQGPRG 651 Query: 255 AAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAAAAAAAA 309 K +G AG PG G G+PG GA GI G G G A Sbjct: 652 LPGTPGTDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGEKGPEGA 709 Query: 310 AAKAAKYGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG-AGIPVV 354 K G + P GP PG G GA G PG G PG AG Sbjct: 710 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 769 Query: 355 PGA-GIPG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 PGA G PG A PG P A G + G G P G Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP----G 825 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-----V 455 A GFPG G G PG G PG G PG G G + +A + GL Sbjct: 826 ATGFPG-AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGLQGPAGP 883 Query: 456 PGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK 514 PG PG G PG GLA G+ G+ G PG+ PG K A Sbjct: 884 PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEPGKQGAP 941 Query: 515 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 574 A+ + G PG VG PGL AG PG G PG PG AA Sbjct: 942 GASGDR---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRDGAA--- 983 Query: 575 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVG 634 GV G G G VG PG GP + A K G GA G G G Sbjct: 984 -------GVKGDRGETGAVGAPG---APGPPGSPGPAGPTGKQGDRGEAGAQGPMGPS-G 1032 Query: 635 GLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G+ G G P +A + G GL G G G L G+ PG Sbjct: 1033 PAGARGIQGPQG-PRGDKGEAGEPGERGLKGHRGFTG---LQGLPGPPG 1077 Score = 143 bits (361), Expect = 5e-34 Identities = 226/731 (30%), Positives = 261/731 (35%), Gaps = 113/731 (15%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLGA 77 P G PG PG G+PG G A G +GP G P +P P G GA Sbjct: 472 PKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP 530 Query: 78 GLGAFPAVT-------------FPGAL----VPGGVADAAAAYKAAKAGA----GLGGVP 116 G+ FP PGA +PG + AA AG G G P Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590 Query: 117 GVGGLGVSAGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-FPGV 163 G G G P PG G KPG VPG G PG+ +PG PGA+ G Sbjct: 591 GPSGFQGLPGPPGP-PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 649 Query: 164 GVLPGVPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGYPIK 209 LPG P G K + PG G G+PG GP G + V P Sbjct: 650 RGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKGPEG 708 Query: 210 APKLPGGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAA 260 AP GG GL G P G GP G AG+AG G P G GP A A Sbjct: 709 APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAG 768 Query: 261 KAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAK 315 A GA G G G G PG PG G GV P A A A Sbjct: 769 PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 828 Query: 316 YGAAAGLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPGA-A 363 + AAG V P G PG G PG G G G PG AG P + G AG PG Sbjct: 829 FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888 Query: 364 VPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV 423 PG P A G R G+ G+P G GFPG +PG +G PG Sbjct: 889 EPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGEPGK 937 Query: 424 GGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG 481 G PG G G + P A + + G +PG PG A GV G Sbjct: 938 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKGDRG 990 Query: 482 VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGV 540 A G APG +PG P G + A+ + + GA GI G G Sbjct: 991 ETGAVGAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048 Query: 541 PGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGALGG 592 G G GL G G +PG A+ A G PG +G G G Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGA 1108 Query: 593 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 652 GIPG + GP + A G G G G G+ G+G P Sbjct: 1109 NGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQ 1168 Query: 653 AKAAKYGAAGL 663 A A GL Sbjct: 1169 YMRADQAAGGL 1179 Score = 134 bits (337), Expect = 3e-31 Identities = 212/676 (31%), Positives = 238/676 (35%), Gaps = 100/676 (14%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 49 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 94 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 PG P G + A AG G G LGV G + P G PG Sbjct: 95 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRG-PPGPAGAP 149 Query: 145 GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPL 204 G G PG PGV G P G P PG G AG PG GP PG Sbjct: 150 GPQGFQGNPGEPGE--PGVSGPMG-PRGPPGPPGKPGDDGE-AGKPGKAGERGP-PG--- 201 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAA 264 P A PG GLP G Y G+ GA G+AG P GV ++ + Sbjct: 202 --PQGARGFPGTPGLPGVKGHRGYP----GLDGAKGEAGAP---GVKGESGS-------- 244 Query: 265 KFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVP 324 PG G+ P P +PG G G A AA A + G A P Sbjct: 245 ----------PGENGSPGPMGPRGLPGERGRTG-----PAGAAGARGNDGQPGPAGPPGP 289 Query: 325 GGPGFGPGVVGVPG----AGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAK 379 GP GPG G PG AG G G GA P G PG PG P A+ Sbjct: 290 VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP----RGEPG--TPGSPGPAGASGNPGT 343 Query: 380 AAKYGARPGVGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 GA+ G GI GA GFPG G G G G G G PG+ G G Sbjct: 344 DGIPGAKGSAGAPGI----AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ- 398 Query: 438 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV--APGVGLAPGVGVAPGVGVAPGVG 495 P+ + A G G G GVG PG APG PG G Sbjct: 399 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 458 Query: 496 VAPG-IGPGGVAA--AAKSAAKVAAKAQLRAAAGL-----GAGIPGLGVGVGVPGLGVGA 547 APG GP G+A A + L A GL AG G G PG Sbjct: 459 GAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRP 518 Query: 548 GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAA 607 G PG G PG PG K A G G GA G G+PG G A Sbjct: 519 GPPGPQGARGQPGVMGFPG----PKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP 574 Query: 608 AAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVL 667 A A + + G G +G GL G PG G GG P G AG G++ Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLP----GPPGPPGEGGKPGDQGVP----GEAGAPGLV 626 Query: 668 GGAGQFPLGGVAARPG 683 G G+ G PG Sbjct: 627 GPRGERGFPGERGSPG 642 Score = 129 bits (324), Expect = 9e-30 Identities = 194/612 (31%), Positives = 217/612 (35%), Gaps = 86/612 (14%) Query: 111 GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP 170 G G PG G AG P+ G K K G PG PG PG PG P Sbjct: 48 GPKGPPGPQG---PAGEQGPRGDRGDKGEK----GAPGPRGRDGEPGT--PGNPGPPGPP 98 Query: 171 TGAGVKPKAPGVGGAFAGIPGVG---PFGGPQPGV---PLGYPIKAPKLPGGYGLPYTTG 224 P PG+GG FA G GG Q GV P+G P+ PG G P Sbjct: 99 G----PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG-PMGPRGPPGPAGAP---- 149 Query: 225 KLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVL-----PGVG 278 GP G G G+ G P +G +GP+ K AG G PG Sbjct: 150 ------GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203 Query: 279 GA-GVPGVPGAIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV 333 GA G PG PG +PG+ G G G A A ++ G P GP PG Sbjct: 204 GARGFPGTPG-LPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262 Query: 334 VGVPG-AGVPGV----GVPGAGIPVVP-----GAGIPGAAVPGVVSPEAAAKAAAKAAKY 383 G G AG G G PG P P G G PGA PG A Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGA--PGAKGEAGPTGARGPEGAQ 320 Query: 384 GARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G R G G P GA G PG G+ G G AG PG+ G PG G G P Q Sbjct: 321 GPRGEPGTPGSPG-PAGASGNPGTD-GIPGAKGSAGAPGIAGAPGFPGPRG---PPGPQG 375 Query: 444 AAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPG 503 A K G PG+ G G G APG G A G PG Sbjct: 376 ATGPLGPK-----GQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG-EPG 429 Query: 504 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPG---LGVGVGVPGLGVGAGVPGLGVGAGVPG 560 GV R A G G PG L G PG +G+ G G PG Sbjct: 430 GVGPIGPPGE--------RGAPG-NRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480 Query: 561 FGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 620 PG A+ PG G G +G G PG GP A Sbjct: 481 RPGEPGL----PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP 536 Query: 621 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 680 G GA G G G G+PG GL G+P K + GAAG G G AG+ G Sbjct: 537 GPKGANGEPGKA-GEKGLPGAPGLRGLP----GKDGETGAAGPPGPAGPAGERGEQGAPG 591 Query: 681 RPGFGLSPIFPG 692 GF P PG Sbjct: 592 PSGFQGLPGPPG 603 Score = 122 bits (307), Expect = 9e-28 Identities = 156/500 (31%), Positives = 174/500 (34%), Gaps = 50/500 (10%) Query: 214 PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV 273 PG G G + GP G G G AG GP+ + A G G Sbjct: 31 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQ-----GPRGDRGDKGEKGAPGPRGRDGE 85 Query: 274 LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAG-LVPGGPGFGPG 332 G G PG PG PG G+ G A A A+ G G + P GP PG Sbjct: 86 PGTPGNPGPPGPPGP-PGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG 144 Query: 333 VVGVPGA----GVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARP 387 G PG G PG G PG P+ P G PG PG + A KA + G Sbjct: 145 PAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGKPGDDGEAGKPGKAGERGPPG 201 Query: 388 GVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAA 444 G G P G G PG G G PG+ G G G PGV G PG SP Sbjct: 202 PQGARGFP----GTPGLPGVK-GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 445 AAAKAAKYGLVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGP 502 + P G A G PG PG VG A G G G G GP Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316 Query: 503 GGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 561 G + A+ G GIPG G PG+ AG PG G PG Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI---AGAPGFPGPRGPPGP 373 Query: 562 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 621 G L K PG+ G G G G PG AGP A A K Sbjct: 374 QGATGPLGP----KGQTGEPGIAGFKGEQGPKGEPGP---AGPQGAPGPAGEEGKR---- 422 Query: 622 LVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAAR 681 GA G G GVG +G PG G G G GL G G G+ G+A Sbjct: 423 --GARGEPG-GVGPIGPPGERGAPG-------NRGFPGQDGLAGPKGAPGERGPSGLAGP 472 Query: 682 PGFGLSPIFPGGACLGKACG 701 G P PG L A G Sbjct: 473 KGANGDPGRPGEPGLPGARG 492 Score = 122 bits (305), Expect = 1e-27 Identities = 154/482 (31%), Positives = 173/482 (35%), Gaps = 53/482 (10%) Query: 232 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPG 287 PG + G G P GPQ A + G G PG G G PG PG Sbjct: 40 PGDIKDIVGPKGPP-----GPQGPAGEQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGNPG 93 Query: 288 --AIPGIGGIAGVGTPAAAAAAAA---AAKAAKYGAAAG-LVPGGPGFGPGVVGVPG--- 338 PG G G+G AA A A A+ G G + P GP PG G PG Sbjct: 94 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 153 Query: 339 -AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 396 G PG G PG P+ P G PG PG + A KA + G G G P Sbjct: 154 FQGNPGEPGEPGVSGPMGP-RGPPGP--PGKPGDDGEAGKPGKAGERGPPGPQGARGFP- 209 Query: 397 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAAAAAKAAKYG 453 G G PG G G PG+ G G G PGV G PG SP + Sbjct: 210 ---GTPGLPGV-KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265 Query: 454 LVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 511 P G A G PG PG VG A G G G G GP G Sbjct: 266 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325 Query: 512 AAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 570 + A+ G GIPG G PG+ AG PG G PG G L Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI---AGAPGFPGPRGPPGPQGATGPL-- 380 Query: 571 AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAG 627 K PG+ G G G G PG G GA GPA A + G +G G Sbjct: 381 --GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 438 Query: 628 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQ-----FP-LGGVAAR 681 G G G PG GL G P A + G AG G G G+ P G+ R Sbjct: 439 ERG-APGNRGFPGQDGLAG-PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 496 Query: 682 PG 683 PG Sbjct: 497 PG 498 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 172 bits (435), Expect = 1e-42 Identities = 247/821 (30%), Positives = 300/821 (36%), Gaps = 151/821 (18%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPGP 651 Query: 122 GVSAGAVVPQPGAGVKPGKVPG----VGLPGV--------YPGGVLPGAR----FPGVGV 165 G + QPG PG PG VGLPG PG +PG++ PG+G Sbjct: 652 KGDPGQTITQPGKPGLPGN-PGRDGDVGLPGDPGLPGQPGLPG--IPGSKGEPGIPGIG- 707 Query: 166 LPGVPTGAGVK-----PKAPGVGGAFA--GIPGVGPFGGP--QPGVPLGYPIKAPKLPG- 215 LPG P G P APG G G PG F GP +PG L P P LPG Sbjct: 708 LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767 Query: 216 ----------GY----GLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAA 259 G+ G P TG LP G G G G G P G+G Q Sbjct: 768 KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827 Query: 260 AKAAAKFGAGAAGVL-----PGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAA 311 G G+ PG G VPG PG PGI G G +G P + A Sbjct: 828 GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----------GVPGA----------G 350 + G + GP PG +G+PG +GVPG+ G+PG G Sbjct: 888 ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947 Query: 351 IPVVPGA---------------GIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPGV---- 389 +P PG G+PG +PGV P+ + G +PG+ Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPG--IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005 Query: 390 ---GVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG- 434 G G+P +G GFPG GV G PG +GVPG G PG+ G G Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG-PQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 435 ---VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 491 GIS + GL PG PG+ + G PG+ PG PG+ Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGL-PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123 Query: 492 PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG 551 PG PG P G++ + + G G PG G PG G G Sbjct: 1124 PGTPGPPG--PKGISGPPGNPGLPGEPGPV--GGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 552 LGVGAGVPGFGAV-PGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVGA-GP 604 G PGFG P L K +PG+ G G G G PG GV G GP Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 605 AAAAAAAKAAAKA-----AQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--------PAA 651 + A K G G G GL G G PG+ G GGI P Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP-GPEGPPGLPGNGGIKGEKGNPGQPGL 1298 Query: 652 AAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 G G G+ G G+ L G+ PG P FPG Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1339 Score = 165 bits (418), Expect = 1e-40 Identities = 227/788 (28%), Positives = 285/788 (36%), Gaps = 174/788 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G GL P Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI---PGLPGDPG-- 319 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGL 146 +PG PG + K K G G PG+ V+P+PG G+ G+ +GL Sbjct: 320 YPGE--PGRDGE-----KGQKGDTGPPGPPGL---------VIPRPGTGITIGEKGNIGL 363 Query: 147 PGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGV 202 PG LPG + FPG+ PG+P G P F G G GP PG+ Sbjct: 364 PG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGP-PGI 416 Query: 203 PLGYPIKAPKLPGGYGLPYTTGKLPYGY-----------GPGGVAGAAGKAGYPTGTGVG 251 + P PG GLP G P G GP G G+ G G GV Sbjct: 417 SIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGV- 473 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAA 311 K F G+ G G+PG+PG +G G A A Sbjct: 474 ------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIPVVPGAGIPG 361 GA PG PGF PG G PG G+ G +G PGA G+P +PG PG Sbjct: 528 LPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT--PG 579 Query: 362 A-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG----VGVGGIPG 416 +PG+ P+ + G G+ G+P +G G PGFG VG GI G Sbjct: 580 QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPGPVGEKGIQG 638 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--------PGVGVAPGVGVAP 468 VAG PG G+PG G PG I+ + + G V PG PG+ + Sbjct: 639 VAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSK 698 Query: 469 GVGVAPGVGLA--------PGVGVAPGVGVAPG-VGVAPGIGPGGV-------------- 505 G PG+GL PG+ PG PG +G+ GP G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 506 -----------AAAAKSAAKVAAKAQLRAAAGLGA-----------GIPGLGVGVGVPGL 543 A K GL G PG G+PG+ Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 544 GVGA--GVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 601 GV G PG+ G PG +PG G VPG G G+ G G PG + Sbjct: 819 GVQGPPGPPGIPGPIGQPGLHGIPGE--KGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 602 AG----PAAAAAAAKAAAKAAQFGLVGAAGLGG-LGVGGL-GVPGVGGLGGI-------- 647 G P A A+ K + G++G G G LG+ G GVPG+ G G+ Sbjct: 877 PGSPGLPGKAGASGFPGTKG-EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPG 935 Query: 648 ---------------PPA--------AAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 PP + + + G G+ GV G G L G +PG Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 685 GLSPIFPG 692 P PG Sbjct: 996 SGQPGLPG 1003 Score = 162 bits (409), Expect = 1e-39 Identities = 228/721 (31%), Positives = 274/721 (38%), Gaps = 143/721 (19%) Query: 24 SRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 S P G PG +PG G PG + +PG GA GP G P +PG G G Sbjct: 490 SGPPGQPG-LPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP--GIPGAPGAPGFPGSKGE 546 Query: 82 -FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 +TFPG K K G G PG+ GL PG + G Sbjct: 547 PGDILTFPGM-------------KGDKGELGSPGAPGLPGL----------PGTPGQDG- 582 Query: 141 VPGVGLPGVYPGGV-LPGARFP-GVGVLPGVPTGAG-VKPKAPGVGGAFA--GIPGVGPF 195 +PG+ P PGG+ G R P G LPG+P G + P G G GI GV Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVA-- 640 Query: 196 GGP-QPGVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGP 252 G P QPG+P G P + PG GLP G+ G G+ G G G P G+ Sbjct: 641 GNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGR----DGDVGLPGDPGLPGQPGLPGI-- 694 Query: 253 QAAAAAAAKAAAKFGAGAAGV-LPGVGGA-GVPGVPG--AIPGIGGIAGVGTPAAAAAAA 308 +K G G+ LPG G G PG+PG PG G G+ P Sbjct: 695 ---------PGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP------- 738 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-------GIPG 361 PG PGF PG G PG +PG P G+P GA G PG Sbjct: 739 ---------------PGPPGF-PGPKGEPGFALPGPPGP-PGLPGFKGALGPKGDRGFPG 781 Query: 362 AAVP-------GVVSPEAAAKAAAKAAKYG--ARPGVGVGGIPTYGVGAGGFPG--FGVG 410 P G+ P+ + G PG+GV G P G G PG G Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP----GPPGIPGPIGQPG 837 Query: 411 VGGIPG-----------VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 459 + GIPG V G PG G PG+ G PG I P KA G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG-PIGPPGSPGLPGKAGASGF-PGTK 895 Query: 460 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAK 518 G+ PG PG PG PG+ G+ PG+ GP G +K + Sbjct: 896 GEMGMMGPPG---PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTG-EKGSKGEPGLPGP 951 Query: 519 AQLRAAAGLGA----GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 574 LG+ G PGL G+PG+ G GL G PG PG L Sbjct: 952 PGPMDPNLLGSKGEKGEPGL---PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGP 1007 Query: 575 KYGAAVPGVLG-----GL-GALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGA 625 K +PG G GL G +G +G PG GV G GP+ + Q G G Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067 Query: 626 AGLGGLGVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 G+ +G+ GL G G GL G P P G GL G G GQ L G P Sbjct: 1068 PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTP 1127 Query: 683 G 683 G Sbjct: 1128 G 1128 Score = 159 bits (402), Expect = 8e-39 Identities = 223/729 (30%), Positives = 270/729 (37%), Gaps = 107/729 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAGAVVP----- 130 G PG +PG A+ + K G+ G PG G LG+ + VP Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 131 -----QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 184 QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 185 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 241 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 242 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 290 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 291 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 344 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 345 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP----- 395 G+PG PV G G PG P G + A + + G +PG G G P Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGL 1200 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP-EAQAAAAAKAAKYGL 454 + G GG PG G G+PG G PG G PGV G PG SP A G Sbjct: 1201 SGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQG- 1258 Query: 455 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAK 510 PG G PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1259 PPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1318 Query: 511 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 570 K G PGL G PG+ +GVPG G PG PG Sbjct: 1319 RPGLNGMK-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1367 Query: 571 AKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 630 + + G G G G G+ G GP + GL G G GG Sbjct: 1368 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1427 Query: 631 -LGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGG-----------AGQFPLGG 677 G GL G PG GL G PP G G V G A Q P G Sbjct: 1428 RKGDPGLPGQPGTRGLDG-PPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGT 1486 Query: 678 VAARPGFGL 686 + GF L Sbjct: 1487 LQVYEGFSL 1495 Score = 158 bits (400), Expect = 1e-38 Identities = 225/735 (30%), Positives = 277/735 (37%), Gaps = 114/735 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPG--GLAGAGLGAGLGAFPAV 85 G PGA G PG +PG G G G P +PG GL G GL P Sbjct: 386 GPPGAAVMGPPGPPGFPGER------GQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439 Query: 86 TFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGG---------LGVSAGAVVPQPGAG 135 P + + G GL G GV G +G QPG Sbjct: 440 AGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 136 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-- 192 PG +G PG GA P G+ +PG P G P + G G PG+ Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGF-PGSKGEPGDILTFPGMKG 558 Query: 193 --GPFGGP-QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 G G P PG+P P PG GLP G P G PGG+ G+ G P G Sbjct: 559 DKGELGSPGAPGLP-----GLPGTPGQDGLPGLPG--PKGE-PGGIT-FKGERGPPGNPG 609 Query: 250 VGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAG--VGTPAAAAA 306 + P FG G G G AG PG PG IPG G G + P Sbjct: 610 L-PGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG-IPGPKGDPGQTITQPGKPGL 667 Query: 307 AAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA----GVPGVGVPGA----GIPVVPG 356 + G +PG PG PG+ G+PG+ G+PG+G+PG G P +PG Sbjct: 668 PGNPGRDGDVG-----LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722 Query: 357 A-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--- 412 G PG PG + E G PG + G P G G PGF +G Sbjct: 723 PPGAPGT--PGRIGLEGPPGPPGFPGPKG-EPGFALPGPP----GPPGLPGFKGALGPKG 775 Query: 413 --GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA--PGVGVAP 468 G PG G PG G+ G+ G G + P Q +PG+GV PG P Sbjct: 776 DRGFPGPPGPPGRTGLDGLPGPKG-DVGPNGQPGPMGPPG----LPGIGVQGPPGPPGIP 830 Query: 469 GVGVAPGVGLAPG-----------VGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 516 G PG+ PG V PG +PG+ APG IGP G + A + Sbjct: 831 GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPG-SPGLPGKAGAS 889 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 + G+ G PG +G+PG +GVPGL G+ G +PG K +K Sbjct: 890 GFPGTKGEMGM-MGPPGPPGPLGIPGR---SGVPGLKGDDGLQGQPGLPGP-TGEKGSKG 944 Query: 577 GAAVPG--------VLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 628 +PG +LG G G G+PG +GP K Q GL G G Sbjct: 945 EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP-----------KGYQ-GLPGDPGQ 992 Query: 629 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 688 GL G G+PG G G P + G GL G +G G GV PG P Sbjct: 993 PGLS-GQPGLPGPPGPKG-NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVP 1050 Query: 689 IFPGGACLGKACGRK 703 PG L G K Sbjct: 1051 GQPGSPGLPGQKGDK 1065 Score = 129 bits (323), Expect = 1e-29 Identities = 207/730 (28%), Positives = 253/730 (34%), Gaps = 150/730 (20%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGA 81 HP PG PG P G PG G G G P P P G+ G GL Sbjct: 58 HPGLPG-FPG--PEGPPGP------------RGQKGDDGIPGPPGPKGIRGP---PGLPG 99 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKV 141 FP PG +PG A G G+PG G G PG+ PG Sbjct: 100 FPGT--PG--LPGMPGHDGAP--------GPQGIPGCNGTKGERGF----PGSPGFPGLQ 143 Query: 142 PGVGLPGVYPGGVLPGARF-PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 200 G PG+ PG + PG ++ +P G P PG G G+PG P G P P Sbjct: 144 GPPGPPGI------PGMKGEPGSIIMSSLPGPKG-NPGYPGPPG-IQGLPG--PTGIPGP 193 Query: 201 GVPLGYP-IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAA 258 P G P + P PG GLP G + + GP G G G G P GP + Sbjct: 194 IGPPGPPGLMGP--PGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPP-----GPPGQISE 246 Query: 259 AAKAA-AKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKY 316 + +F G G+ G G PG+ G GG G G K + Sbjct: 247 QKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306 Query: 317 GAAAGLVPGGPGFGPGVVGVPGA-------------GVPGVGVPGAGIPVVPGA------ 357 G +PG PG PG G PG G PG+ +P G + G Sbjct: 307 GQPG--IPGLPG-DPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGL 363 Query: 358 -GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF----- 407 G+PG PG+ P PG V G P G GFPG Sbjct: 364 PGLPGEKGERGFPGIQGPPGLP----------GPPGAAVMGPP----GPPGFPGERGQKG 409 Query: 408 -----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAP 462 G+ + G PG+ G PG G+PG G G I P + G G+ Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469 Query: 463 GVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR 522 GV G + G+ PG PG+ PG PG + + K +A Sbjct: 470 EQGVKGDKGDTCFNCIGTGISGPPG---QPGLPGLPG-PPGSLGFPGQKGEK--GQAGAT 523 Query: 523 AAAGLGAGIPGLGVGVGVPG--------------------LGVGAGVPGLGVGAGVPGFG 562 GL GIPG G PG LG G PGL G PG Sbjct: 524 GPKGL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELG-SPGAPGLPGLPGTPGQD 581 Query: 563 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 622 +PG L K G G G G G G+PG + GP G Sbjct: 582 GLPG-LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP----------GP 630 Query: 623 VGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARP 682 VG G+ G+ G G PG+ G G P + K G G G G G G+ +P Sbjct: 631 VGEKGIQGV-AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 683 GFGLSPIFPG 692 G P PG Sbjct: 690 GL---PGIPG 696 Score = 73.6 bits (179), Expect = 6e-13 Identities = 118/410 (28%), Positives = 141/410 (34%), Gaps = 73/410 (17%) Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 349 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 350 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 409 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 470 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 522 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 523 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 577 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 578 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 637 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 638 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLS 687 PG+ GL G P + + G G G G G P G V RPG G++ Sbjct: 308 QPGIPGLPG-DPGYPGEPGRDGEKGQKGDTGPPG--PPGLVIPRPGTGIT 354 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 170 bits (430), Expect = 5e-42 Identities = 232/737 (31%), Positives = 292/737 (39%), Gaps = 116/737 (15%) Query: 23 PSRPG--GVPGAIPG------GVPGGV----FYPGAGLGALGGGALGPGGKPLKPVPGGL 70 P PG G PG G G+PG + F G+ AL GG GP GK P P GL Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439 Query: 71 AGA--------GL--GAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVG 119 G GL G FP + PGA P G A + + + G+PG+ Sbjct: 440 PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLP 499 Query: 120 GLGVSAGAVVPQPGAGVKPGKVPGVGLPGV-----YPGGV-LPGAR----------FPGV 163 G AG + +PG G GLPG PG + PG + G Sbjct: 500 GPKGFAG-INGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGE 558 Query: 164 GVLPGVPTGAGVK--PKAPGVGG--AFAGIPG------VGPFGGP-QPGVPLGYPIKAPK 212 PGVP G+K +PG G F G+PG GP G P PG+P Sbjct: 559 RGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEM 618 Query: 213 LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAG 272 P G GLP G+ + G G+ G G G P G Q K A G Sbjct: 619 GPPGLGLPGLKGQRGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GDRQEA 676 Query: 273 VLPG-VGG-AGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYG-AAAGLVPGGPG 328 + PG +GG G+PG+PG PG G G+ G P A A G A PG PG Sbjct: 677 IQPGCIGGPKGLPGLPGP-PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPG 735 Query: 329 F-GP----GVVGVPGA-GVPG-VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKA 380 F GP G VG+PG G PG +G+PG P PG G+PG + P A Sbjct: 736 FIGPRGSKGAVGLPGPDGSPGPIGLPGPDGP--PGERGLPGEVLGAQPGPRGDA------ 787 Query: 381 AKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPE 440 G G+ G+P G G PGF G G+PG+ G+ G G+PG G PG+ Sbjct: 788 ---GVPGQPGLKGLP----GDRGPPGFR-GSQGMPGMPGLKGQPGLPGPSGQPGL----- 834 Query: 441 AQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG- 499 YG PG+ PG APG G+ PG PG PG APG Sbjct: 835 -----------YG-PPGLHGFPG---APGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGP 879 Query: 500 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 559 +G G++ A + + G G+ G PGL G PG+ G+P Sbjct: 880 VGMKGLSGDRGDAGFTGEQGHPGS-----PGFKGIDGMPGTPGLKGDRGSPGMDGFQGMP 934 Query: 560 GFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKA 617 G PG +K +PG+ G G G G G G G P + Sbjct: 935 GLKGRPG-FPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEK 993 Query: 618 AQFGLVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 675 G +G G LG G+ G+ G+PG+ G+ G+P G G+ G+ G G FP Sbjct: 994 GDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPG-FP- 1051 Query: 676 GGVAARPGFGLSPIFPG 692 GVA PG P F G Sbjct: 1052 -GVAGPPGITGFPGFIG 1067 Score = 153 bits (387), Expect = 5e-37 Identities = 239/807 (29%), Positives = 289/807 (35%), Gaps = 158/807 (19%) Query: 21 LHPSRPGGVPGAIP---------GGVPGGVFYPGA-----GLGALGGGALGPGGKPLKPV 66 L P P G PG I GG PG GL L G G K L+ + Sbjct: 647 LGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGI 706 Query: 67 PGGLAGAGLGAGLGAFPAVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL- 121 PG AGA G G P FPG PG + + K A G G PG GL Sbjct: 707 PG-FAGADGGPGPRGLPGDAGREGFPGP--PGFIGPRGS--KGAVGLPGPDGSPGPIGLP 761 Query: 122 ---GVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVPTGAG 174 G +P G +PG G+PG LPG R P G +PG+P G Sbjct: 762 GPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMP-GLK 820 Query: 175 VKPKAPGVGG--AFAGIPGVGPF-GGPQPGVPLGYPIKAPK--LPGGYGLPYTTGKL-PY 228 +P PG G G PG+ F G P PLG P + LPG G P TG P Sbjct: 821 GQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPV 880 Query: 229 GY----GPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 283 G G G AG G+ G+P G G + G G G G P Sbjct: 881 GMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRP 940 Query: 284 GVPGA--------IPGIGGIAGV-------------GTPAAAAAAAAAAKAAK------- 315 G PG+ IPG+ G+AG G P K K Sbjct: 941 GFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMG 1000 Query: 316 ---YGAAAGL--VPGGPGFG--PGVVGVPG--AGVPG-VGVPGA-GIPVVPG-AGIPG-A 362 Y A G+ +PG PG PG+ G PG GV G +GVPG G+P PG AG PG Sbjct: 1001 LKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGIT 1060 Query: 363 AVPGVVSPEAAAKAAAKAAKYG------------------ARPGV----GVGGIPTYGVG 400 PG + A +A YG RPG+ G GIP G Sbjct: 1061 GFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIP----G 1116 Query: 401 AGGFPGF-----GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 455 GF G +G GI GV GV G G+ G G PG+ P +Q + + GL Sbjct: 1117 LKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQG----ELGRIGLP 1172 Query: 456 PGVGV-----APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA--PGI-GPGGVAA 507 G G APG+ PG+ G+ PG PG +PG + PG GP G Sbjct: 1173 GGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPG---SPGSDIHGDPGFPGPPGERG 1229 Query: 508 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA 567 A + + G G PG G PGL G+ +G PG PG Sbjct: 1230 DPGEANTLPGPVGVPGQKG-DQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGI 1288 Query: 568 LA-----AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAG-------PAAAAAAAKAAA 615 AA+PG G G G G PG AG P + Sbjct: 1289 FGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGP 1348 Query: 616 KAAQFGLVGAAG-LGGLG-------------VGGLGVPGVGGLGGIPPAAAAKAAKYGAA 661 + Q G +G G G +G G G G G+ GIP A + G Sbjct: 1349 RGEQ-GFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQ 1407 Query: 662 GLGGVLGGAGQFPLGGVAARPGFGLSP 688 G G G G+ G PGF +P Sbjct: 1408 GRRGPPGAPGEMGPQGPPGEPGFRGAP 1434 Score = 152 bits (384), Expect = 1e-36 Identities = 241/814 (29%), Positives = 292/814 (35%), Gaps = 181/814 (22%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPG--AGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P RPG V P G PG PG G G LG G V G G G Sbjct: 198 PGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYG-----VKGEKGDVG-QPGPN 251 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP----QPG-AG 135 P+ T + P GV YK K G G+ G+ G P PG +G Sbjct: 252 GIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSG 311 Query: 136 VK--PGKVPGVGLPGVY--------------PG-----------GVLPGAR----FPGVG 164 K PG+ GL G PG + GAR FPG Sbjct: 312 EKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQ 371 Query: 165 VLP---GVPTGAGVKPKAPGV----GGAFAGIPG-VGPFGG-PQPGVPLGY-----PIKA 210 P G P G+ P PG+ G G+PG +GP G PG+P Y P Sbjct: 372 GEPGSQGEPGDPGL-PGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGK 430 Query: 211 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAG 269 PG GLP G + +G G G AG G P G GP+ A + G Sbjct: 431 RGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDE 490 Query: 270 AAGVLPGVGG----AGVPGVPG--------------AIPGIGGIAG-VGTPAAAAAAAAA 310 A LPG+ G AG+ G PG PG+ G+ G +G P A + Sbjct: 491 AIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDS 550 Query: 311 AKAAKYGAAA--------------------GL-----VPGGPGFG-------PGVVGVPG 338 G GL +PG PG G PG G+PG Sbjct: 551 RTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPG 610 Query: 339 A-------GVPGVGVPG----------AGIPVVPG-AGIPG-AAVPGVVSPEAAAKAAAK 379 G PG+G+PG AG+P PG G PG A PG + + K A Sbjct: 611 TKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG 670 Query: 380 AAKYGA-RPGV-----GVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 + A +PG G+ G+ PT G G PGF G G PG G+PG G G Sbjct: 671 GDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF-AGADGGPGPRGLPGDAGREG 729 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG--VGLAPGVGVAP 486 G PG I P A G +G+ PG PG PG +G PG Sbjct: 730 FPGPPGF-IGPRGSKGAVGLPGPDGSPGPIGL-PGPDGPPGERGLPGEVLGAQPGPRGDA 787 Query: 487 GVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGV 545 GV PG+ PG GP G R + G+ G+PGL G PGL Sbjct: 788 GVPGQPGLKGLPGDRGPPG----------------FRGSQGM-PGMPGL---KGQPGLPG 827 Query: 546 GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPA 605 +G PGL G+ GF PG + +PG+ G G G G PG GP Sbjct: 828 PSGQPGLYGPPGLHGFPGAPG-------QEGPLGLPGIPGREGLPGDRGDPGDTGAPGPV 880 Query: 606 AAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAA 661 + A G G G G G+ G+ G PG+ G G P G Sbjct: 881 GMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRP 940 Query: 662 GLGGVLGGAGQF---PLGGVAARPGFGLSPIFPG 692 G G G AG F L G+A PGF S PG Sbjct: 941 GFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPG 974 Score = 126 bits (316), Expect = 8e-29 Identities = 213/732 (29%), Positives = 266/732 (36%), Gaps = 117/732 (15%) Query: 44 PGAGLGALGGGALGP--GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAA 101 P G GG P GG+ +P P G G GL FP + Sbjct: 41 PCGGRDCSGGCQCYPEKGGRG-QPGPVGPQGYNGPPGLQGFPGL---------------- 83 Query: 102 AYKAAKAGAGLGGVPGVGGLGVSAGA--VVPQPGAGVKPGKVPGVGLPGVYPG------- 152 + K G G PGV G GA V PGA PG PG G P PG Sbjct: 84 --QGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGH-PGQGGPRGRPGYDGCNGT 140 Query: 153 -GVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA-------------GIPGVGPFGGP 198 G PG G P G K + G +A G PG+ F GP Sbjct: 141 QGDSGPQGPPGSEGFTGPPGPQGPKGQK---GEPYALPKEERDRYRGEPGEPGLVGFQGP 197 Query: 199 QPGVPLGY-----PIKAPKLPGGYGLPYTTGKLPY-GYGPGGVAGAAGKAGYPTGTGVGP 252 PG P G+ P+ AP PG G P G+ G G GV G G G P G+ Sbjct: 198 -PGRP-GHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPS 255 Query: 253 QAAAAAAAKAAAKF------GAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV----GT 300 A F G + PG+ G + G G + PG+ G G+ G+ Sbjct: 256 DTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGS 315 Query: 301 PAAAAAAAA-------AAKAAKYGAAAGLVPGGPGFGP---------GVVGVPGA-GVPG 343 P + + K A PG P + P G G PGA G PG Sbjct: 316 PGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPG 375 Query: 344 V-GVPG-AGIPVVPGAGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY 397 G PG G+P PG I +PG + P+ A YG PG P Sbjct: 376 SQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPG 435 Query: 398 GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG----VGISPEAQAAAAAKAAKYG 453 G G PG + G+ G G G G+PG G G G + E + +A K G Sbjct: 436 PPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIK-G 494 Query: 454 LVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSA 512 L PG+ PG G+ PG G G+ PG+ PG IG G A + Sbjct: 495 L-PGL---PGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDS 550 Query: 513 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL----GVG----AGVPGFGAV 564 + K + R G+ G+PG+ G PG G PGL G G G PG+ + Sbjct: 551 RTITTKGE-RGQPGV-PGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGI 608 Query: 565 PGALAA-AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQFG 621 PG + G +PG+ G G G G+PG G +G P A + Sbjct: 609 PGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGP-PGPAGTPGQIDCDTDVKR 667 Query: 622 LVGAAGLGGLGVGGLGVP-GVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAA 680 VG + G +G P G+ GL G P AK + G G G GG G L G A Sbjct: 668 AVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLR-GIPGFAGADGGPGPRGLPGDAG 726 Query: 681 RPGFGLSPIFPG 692 R GF P F G Sbjct: 727 REGFPGPPGFIG 738 Score = 101 bits (251), Expect = 3e-21 Identities = 154/494 (31%), Positives = 187/494 (37%), Gaps = 110/494 (22%) Query: 23 PSRPGGVPGA-----IPGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAG 74 P RPG + G +PG +PG +PG AG + G G +G G P GL G Sbjct: 1026 PGRPGHIKGVKGDIGVPG-IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGE- 1083 Query: 75 LGAGLGAF----PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV-- 128 +GA G F + PG PG K G G+PG+ G G Sbjct: 1084 IGA-TGDFGDIGDTINLPGR--PG-----------LKGERGTTGIPGLKGFFGEKGTEGD 1129 Query: 129 VPQPG----AGVK--PGKVPGVGLPGVY--PGGV-------LPGAR----FPGVGVLPGV 169 + PG GV+ PG G PG+ PG LPG + +PG LPG Sbjct: 1130 IGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGF 1189 Query: 170 PTGAGVKPK--APGVGGAFAGIPGVGPFGGPQ-PGVP--LGYPIKAPKLPGGYGLPYTTG 224 P G++ PG G F G PG G P PG P G P +A LPG G+P G Sbjct: 1190 PGLRGIRGLHGLPGTKG-FPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKG 1248 Query: 225 K--LPYGYGPGG---------------VAGAAGKAGYPTGTGV----GPQAAAAAAAKAA 263 P GP G ++GA G G P G+ GP +AA Sbjct: 1249 DQGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPG 1308 Query: 264 AKFGAGAAGV--LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAG 321 +K G G PG G P PG+ G+ G P GA Sbjct: 1309 SKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMG--NTGPTGAVGD 1366 Query: 322 LVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIP----VVPGA-------GIPGAAVPGVVS 369 P GP PG G PG VG PG AGIP V PG G PGA PG + Sbjct: 1367 RGPKGPKGDPGFPGAPGT----VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGA--PGEMG 1420 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVG 424 P+ + G R G G G G PGF +G G G G PG Sbjct: 1421 PQGPP------GEPGFRGAPGKAGPQGRG-GVSAVPGFRGDEGPIGHQGPIGQEGAPGRP 1473 Query: 425 GVPGVGGVPGVGIS 438 G PG+ G+PG +S Sbjct: 1474 GSPGLPGMPGRSVS 1487 Score = 60.8 bits (146), Expect = 4e-09 Identities = 94/308 (30%), Positives = 108/308 (35%), Gaps = 63/308 (20%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG PG G PG PG L G PG K + PG G GL Sbjct: 1208 PGSPGSDIHGDPGFPGPPGERGDPGEA-NTLPGPVGVPGQKGDQGAPGERGPPG-SPGLQ 1265 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 FP +T P + + G D G PG+ GL G P PG+ PG Sbjct: 1266 GFPGIT-PPSNISGAPGDK--------------GAPGIFGLKGYRGPPGP-PGSAALPGS 1309 Query: 141 VPGVGLPGV--------YPGGVLPGARFPGVGVLPGV--------------PTGA--GVK 176 G PG + G P R PGV LPG PTGA Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQGR-PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 177 PKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 PK P F G PG VG PG+ G P K PG G G P G G Sbjct: 1369 PKGPKGDPGFPGAPGTVGA-----PGIA-GIPQKIAVQPGTVGPQGRRGP-PGAPGEMGP 1421 Query: 236 AGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGV--------LPG-VGGAGVPGV 285 G G+ G+ G GPQ +A + G G PG G G+PG+ Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGM 1481 Query: 286 PGAIPGIG 293 PG IG Sbjct: 1482 PGRSVSIG 1489 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 158 bits (399), Expect = 2e-38 Identities = 237/770 (30%), Positives = 273/770 (35%), Gaps = 150/770 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----GALGPGGKPLKPVPGGLAGAGLGAG 78 P P G G G PG V PG GA+G GA GP G P P G AG G Sbjct: 397 PEGPQGQRGET--GPPGPVGSPGLP-GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPG 453 Query: 79 LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 G+ P G+ K AG G PG G+ G + P G Sbjct: 454 P--------QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI---QGPIGPPGEEGK 502 Query: 137 K-PGKVPG-VGLPGVYPGGVLPGAR-FPGVGVLPGVPTGA----------GVK------- 176 + P PG VG PG PG R FPG LPG P GA G K Sbjct: 503 RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG-PKGAQGERGPVGSSGPKGSQGDPG 561 Query: 177 -PKAPGVGGA--FAGIPGV-------GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYT 222 P PG+ GA G PGV GP G P +PG P I+ PG GLP Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ--PGSMGLPGP 619 Query: 223 TGKL--PYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVL----- 274 G P G G AG G+ G P G VGP A + G G Sbjct: 620 KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL 679 Query: 275 ------PGVGGA----GVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVP 324 PG GG GVPG PGA+ +G G P + G A G P Sbjct: 680 PGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP 739 Query: 325 GGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG----------------AGIPGA-AV 364 GP PG G PG G PG+ G+PG GI PG AG GA + Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 365 PGVVSPEAAAKAAAKAAKYGARPGVGVGGI-----------PTYGVGAGGFPGFGVGVGG 413 PG + P A + + G R VG G PT GA GF G G G Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT---GAVGFAG-PQGPDG 855 Query: 414 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVA 473 PGV G PG G G G PG P+ A + G VPG+ G PG Sbjct: 856 QPGVKGEPGEPGQKGDAGSPG----PQGLAGSPGPHGPNG-VPGLKGGRGTQGPPGATGF 910 Query: 474 PG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG---- 528 PG G G A G A +G GP G+ S +V + G G Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970 Query: 529 ---------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 573 AG G VG+PG G+PGL AG PG GA Sbjct: 971 PGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATG---- 1026 Query: 574 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV 633 PG +G G+ G VG PG AG A + G G AGL Sbjct: 1027 ---DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL----P 1079 Query: 634 GGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G PG G P A A + G G G +G G+ G+ G Sbjct: 1080 GSQGAPGTPG----PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG 1125 Score = 136 bits (343), Expect = 6e-32 Identities = 225/731 (30%), Positives = 263/731 (35%), Gaps = 137/731 (18%) Query: 23 PSRPG--GVPGAIPGGVPG--GVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAG 78 P RPG G+PGA G+ G GV P LG LG A G G+P P G+ G G Sbjct: 560 PGRPGEPGLPGA--RGLTGNPGVQGPEGKLGPLG--APGEDGRPGPPGSIGIRGQPGSMG 615 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVK 137 L PG G D +A AG G G PG G +G V P PG + Sbjct: 616 L--------PGP--KGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP-PGLAGE 664 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFG 196 G+ G PG P G F G+ PG P G G KP GV G PG VGP G Sbjct: 665 RGEQ---GPPG--PTG------FQGLPGPPG-PPGEGGKPGDQGVPGD----PGAVGPLG 708 Query: 197 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV------ 250 P G P + + PG GLP G + G+GP G G+ G +G P TG Sbjct: 709 ---PRGERGNPGERGE-PGITGLPGEKG-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM 763 Query: 251 -GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAG---------- 297 G + A + G G G G G G+PG + PG G G Sbjct: 764 PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823 Query: 298 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----------------AGV 341 VG P + + + GA P GP PGV G PG AG Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGS 883 Query: 342 PGV----GVPGA----GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVG 392 PG GVPG G PGA G PG+A G V P A A A G G Sbjct: 884 PGPHGPNGVPGLKGGRGTQGPPGATGFPGSA--GRVGPPGPAGAPGPAGPLGEP---GKE 938 Query: 393 GIPTYGVGAGGFPGFGVGVG--GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 450 G P G G PG VG G G G PG G PG G PG P+ A Sbjct: 939 GPP----GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPG----PDGPPGPAGTTG 990 Query: 451 KYGLV--PGVGVAPGVGVAPGVGVAPG----VGLAPGVGVAPGVGVAPGVGVAPGIGPGG 504 + G+V PG G+ PG PG G G VG G GP G Sbjct: 991 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEG 1050 Query: 505 VAAAAKSAAKVAAKAQLR-----AAAGL--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 557 A + + A + AGL G PG VG PG G PG G Sbjct: 1051 PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG 1110 Query: 558 VPGFGA---VPGALAA-AKAAKYG----------------AAVPGVLGGLGALGGVGIPG 597 PG +PG +G +PG G G G GIPG Sbjct: 1111 PPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPG 1170 Query: 598 GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAK 657 GP + G +G G+ G VG G G G G PP Sbjct: 1171 PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRG-SVGEAGPEGPPGEPG-PPGPPGPPGH 1228 Query: 658 YGAAGLGGVLG 668 AA LG ++G Sbjct: 1229 LTAA-LGDIMG 1238 Score = 129 bits (323), Expect = 1e-29 Identities = 230/760 (30%), Positives = 271/760 (35%), Gaps = 145/760 (19%) Query: 11 PGVLLLLLSILHPSRPGGVPGAI-PGGVPGGVFYPGA----GLGALGG-----GALGPGG 60 PG++ ++ I P G PG+ P G G PG G+ G GA GP G Sbjct: 118 PGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177 Query: 61 KPLKPVPGGLAG--AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV 118 P P P GL+ + AGL + L+PG V G G G+ Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPV-----------GPRGPQGL 226 Query: 119 GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK 178 G AG P PG PG + +G G P G PG PG PG + Sbjct: 227 QGQQGGAGPTGP-PGEPGDPGPMGPIGSRG--PEGP-PGK--PGEDGEPG-------RNG 273 Query: 179 APGVGGAFAGIPGVGPFGGPQPGVP-----LGYP-IKAPKLPGGYGLPYTTGKLPYGYGP 232 PG G FAG PG F G PG+P G+ ++ PK G G P + G+ GP Sbjct: 274 NPGEVG-FAGSPGARGFPGA-PGLPGLKGHRGHKGLEGPK--GEVGAPGSKGEAG-PTGP 328 Query: 233 GGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPG--- 287 G G G G P G +GPQ A PG GA G+PG PG Sbjct: 329 MGAMGPLGPRGMPGERGRLGPQGA-------------------PGQRGAHGMPGKPGPMG 369 Query: 288 --AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV------GVPG 338 IPG G G G A A G P GP PG+ G PG Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429 Query: 339 A----GVPGV-GVPG-AGIPVVPG-------AGIPG-AAVPGVVSPEAAAKAAAKAAKYG 384 A G PG G PG AG P PG GI G PGV + A + +G Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG 489 Query: 385 ARPGVGVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG----V 435 + +G G P G G PG VG G PG G PG G+PG G G V Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPG-PVGERGAPGNRGFPGSDGLPGPKGAQGERGPV 548 Query: 436 GIS-PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-----APGVGLAPGVGVAPGVG 489 G S P+ + + GL G+ GV G APG PG + G+ Sbjct: 549 GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIR 608 Query: 490 VAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGVP 541 PG PG G G A Q A G G PGL G Sbjct: 609 GQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ 668 Query: 542 GLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG---- 597 G G GL G PG G PG PG +G LG G G PG Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGV-------PGDPGAVGPLGPRGERGNPGERGE 721 Query: 598 -GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGL-GVPGVGGLGGIP------ 648 G+ G P A + G G +G G G GL G+PG G+ G P Sbjct: 722 PGITGL-PGEKGMAGGHGPDGPK-GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDR 779 Query: 649 -----PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 A A GA GL G LG G G PG Sbjct: 780 GGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819 Score = 85.9 bits (211), Expect = 1e-16 Identities = 120/428 (28%), Positives = 151/428 (35%), Gaps = 45/428 (10%) Query: 276 GVGGAGVPGVPGAIPGIGGIAGVGTPAA-AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV 334 G G G G PG +P + GI G PA + + G P G PGV Sbjct: 108 GRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVP 167 Query: 335 GVPGA-GVPG-VGVPG------------AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKA 380 G PGA G PG PG AG+ G G +PG V P Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227 Query: 381 AKYGARPGVGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 438 + G G PT G G PG +G G G G PG G PG G PG Sbjct: 228 GQQG-------GAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG---- 276 Query: 439 PEAQAAAAAKAAKYGLVPGVGVAPGV-GVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA 497 E A + A + PG+ PG+ G G+ G G G +G Sbjct: 277 -EVGFAGSPGARGFPGAPGL---PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAM 332 Query: 498 PGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 557 +GP G+ A Q R A G+ G PG +G+PG G PG+ AG Sbjct: 333 GPLGPRGMPGERGRLGPQGAPGQ-RGAHGM-PGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390 Query: 558 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 617 G G + + PG +G G G +G G GP + + A Sbjct: 391 PTGARGPEG----PQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSA 446 Query: 618 AQFGLVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 675 G G G G G+ G G PGV G G A + G G+ G +G G+ Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGDPGVPGFKG----EAGPKGEPGPHGIQGPIGPPGEEGK 502 Query: 676 GGVAARPG 683 G PG Sbjct: 503 RGPRGDPG 510 Score = 81.3 bits (199), Expect = 3e-15 Identities = 116/366 (31%), Positives = 134/366 (36%), Gaps = 58/366 (15%) Query: 325 GGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKY 383 G FG G G G PG+ +PVV G G PG A P P + + K Sbjct: 103 GNTNFGRGRKGQKGE--PGL------VPVVTGIRGRPGPAGP----PGSQGPRGERGPK- 149 Query: 384 GARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQ 442 RPG P G+ G PGV G PG G PG PG G+S Sbjct: 150 -GRPG----------------PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFS 192 Query: 443 AAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IG 501 A A K GL VG+ PG V P VG GL G A G PG PG +G Sbjct: 193 AQMAGLDEKSGLGSQVGLMPG-SVGP-VGPRGPQGLQGQQGGAGPTG-PPGEPGDPGPMG 249 Query: 502 PGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAG 557 P G K + G AG PG G PGL PGL G Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGL------PGLKGHRG 303 Query: 558 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 617 G G + A +K A G +G +G LG G+PG GP A Sbjct: 304 HKGLEGPKGEVGAP-GSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGA---------P 353 Query: 618 AQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGG 677 Q G G G G +G LG+PG G G P +A GA G G G G+ G Sbjct: 354 GQRGAHGMPGKPG-PMGPLGIPGSSGFPG-NPGMKGEAGPTGARGPEGPQGQRGETGPPG 411 Query: 678 VAARPG 683 PG Sbjct: 412 PVGSPG 417 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 157 bits (396), Expect = 4e-38 Identities = 207/706 (29%), Positives = 264/706 (37%), Gaps = 92/706 (13%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 602 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 657 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 145 PG+ P G + K GL G PG G S G +PG+ PG V Sbjct: 658 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKG----EPGS---PGLVHLPE 709 Query: 146 LPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLG 205 LPG PG R G LPG P G K PG+ G+ G+PG G G G Sbjct: 710 LPG------FPGPR--GEKGLPGFP-GLPGKDGLPGMIGS-PGLPGSKGATGDIFGAENG 759 Query: 206 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAA 264 PG GL TG + G G+ G G G P G G + + + Sbjct: 760 -------APGEQGLQGLTGHKGF-LGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQ 811 Query: 265 KFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV 323 G++G G +G+PG PG PGI G G GT + K G + Sbjct: 812 PGTPGSSGPYGIKGKSGLPGAPG-FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKG--L 868 Query: 324 PGGPGF--------GPGVVGVPGAGVPG--------VGVPGA-GIPVVPGA-GIPGAAVP 365 PG PG PGV G+P P VG PG G+P +PG G+ G +P Sbjct: 869 PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKG--IP 926 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY-----------------GVGAGGFPGFG 408 G + A + G R G GIP+ G+ GFPG Sbjct: 927 GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 984 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAP 468 G G AG PG G+PG G+PG+ + GL PG+ + G+ P Sbjct: 985 --PRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITGFP 1041 Query: 469 GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG 528 G+ PG + G+ +PG+ PG PG+ G + + K Q + G Sbjct: 1042 GM---PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGFKG 1094 Query: 529 A-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 587 G GL +G PG G G+ G+PG PG A + G +PG G Sbjct: 1095 TKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSGHQ 1150 Query: 588 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGLGG 646 GA+G +G PG + G G G G GV G G+PG G G Sbjct: 1151 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1210 Query: 647 IPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 P K G G G G G G+ PG L + G Sbjct: 1211 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAG 1256 Score = 155 bits (392), Expect = 1e-37 Identities = 227/782 (29%), Positives = 299/782 (38%), Gaps = 175/782 (22%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 726 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVS 124 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 786 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 841 Query: 125 AGAVVPQ-----PGAGVKPGKVPGV-GLPGVYPGGV-LPGARFPGVGVLPGVPTGAGVKP 177 G + PG+ VK G +PG+ GLPG PG V L G+ PG + G+P +G K Sbjct: 842 PGKKGTRGKKGPPGSIVKKG-LPGLKGLPG-NPGLVGLKGS--PGSPGVAGLPALSGPKG 897 Query: 178 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 + VG F G PG+ PG+P P G G+P +TGK+ GP G AG Sbjct: 898 EKGSVG--FVGFPGI-------PGLP-----GIPGTRGLKGIPGSTGKM----GPSGRAG 939 Query: 238 AAGKAG---YPTGTGV----------------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 G+ G P G+ G Q +A + + G AG G Sbjct: 940 TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG 999 Query: 279 GAGVPGVPGAIPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFG 330 G PG+PG I G+ G G G P ++ G + + G PG Sbjct: 1000 LPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGL- 1058 Query: 331 PGVVGVPG-----------AGVPG----------------------VGVPG-----AGIP 352 PG G+PG +G PG +G PG + Sbjct: 1059 PGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVG 1118 Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV- 409 V G+PGA PGV + GA +G G+ +G GFPGF G+ Sbjct: 1119 VSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLH 1174 Query: 410 GVGGIPG-----------VAGVPGVGGVPGVGG---VPGVGISPEAQAAAAAKAAKYGLV 455 G+ G+PG + GVPG G+PG G PG+GI + + G Sbjct: 1175 GLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF- 1233 Query: 456 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAK 514 PG+ G+ APG+ + + PG PG+ G PG GP G + + Sbjct: 1234 PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG---RPGPAGPPGPPGPSSNQGD 1290 Query: 515 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG-LGVGA--GVPGFGAVPGALAAA 571 GIPG G G+ +G+PG LG+ G PGF PG + Sbjct: 1291 TGDPGF--------PGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPP 1342 Query: 572 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 631 + PG+ G G G G+ G P A GL G G+ GL Sbjct: 1343 GDPGF----PGMKGKAGPRGSSGLQGD-----PGQTPTAEAVQVPPGPLGLPGIDGIPGL 1393 Query: 632 -----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGL 686 G +G+ G GL GIP K G +GL G G G L G+ PGF Sbjct: 1394 TGDPGAQGPVGLQGSKGLPGIP-------GKDGPSGLPGPPGALGDPGLPGLQGPPGFEG 1446 Query: 687 SP 688 +P Sbjct: 1447 AP 1448 Score = 149 bits (375), Expect = 1e-35 Identities = 232/799 (29%), Positives = 290/799 (36%), Gaps = 173/799 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 182 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 241 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 242 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 297 Query: 115 VPGVGGLGVSAGAVVPQPGAGVKPGKV--PG-------------VGLPGV-----YPGGV 154 +PG G S G P PG K G + PG +GLPG G V Sbjct: 298 LPGPRGPMGSEGVQGP-PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV 356 Query: 155 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 204 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 357 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 416 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 252 I A LPG GLP GP G G ++G+P G GP Sbjct: 417 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 466 Query: 253 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 297 + K + F A GV P G G PG PG +PG+ G G Sbjct: 467 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 525 Query: 298 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 345 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 526 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 585 Query: 346 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 386 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 586 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 645 Query: 387 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 435 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 646 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 704 Query: 436 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV--------GVAPG 487 PE + K GL PG PG PG+ +PG+ + G APG Sbjct: 705 VHLPELPGFPGPRGEK-GL-PGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPG 762 Query: 488 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 546 G+ G +G G+ V K L G G PG VG PG Sbjct: 763 EQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPGTPGQVGQPGTPGS 817 Query: 547 AGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 604 +G G+ +G+PG PG K + PG + G G G+PG G Sbjct: 818 SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 877 Query: 605 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLG 664 + + A A G G G VG +G PG+ GL GIP G GL Sbjct: 878 KGSPGSPGVAGLPALSGPKGEKG----SVGFVGFPGIPGLPGIP----------GTRGLK 923 Query: 665 GVLGGAGQFPLGGVAARPG 683 G+ G G+ G A PG Sbjct: 924 GIPGSTGKMGPSGRAGTPG 942 Score = 141 bits (356), Expect = 2e-33 Identities = 204/705 (28%), Positives = 271/705 (38%), Gaps = 119/705 (16%) Query: 36 GVPGGVFYPGAGLGALGG-GALGPGGKPLKP----VPG-----GLAGAGLGAGL-GAFPA 84 G+PG PG G +G G GP G+ K PG G+ G GL G Sbjct: 294 GIPG---LPGPR-GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVF 349 Query: 85 VTFPGALVPGGVADAAAAYKAAKAG-------AGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 + GA++ G D G G GVPG+ L GA+ PQ G+K Sbjct: 350 IDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLK 409 Query: 138 -----PGK-------VPGV-GLPGVY--PGGVLPG----------ARFPGVGVLPGVPTG 172 PG+ +PG GLPG PG P + FPG+ G Sbjct: 410 GDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGN 469 Query: 173 AGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK----- 225 G+K G G+P GP G P P P G I P L G G + G Sbjct: 470 LGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGL-IGLPGLKGARGDRGSGGAQGPAG 528 Query: 226 LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 P GP G +G GK G P + + Q + ++ G GV+ G GVPG+ Sbjct: 529 APGLVGPLGPSGPKGKKGEPILSTI--QGMPGDRGDSGSQ---GFRGVIGEPGKDGVPGL 583 Query: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG----PGVVGVPGA-- 339 PG +PG+ G G G P + G PG PG G PG G+PG Sbjct: 584 PG-LPGLPGDGGQGFPGEKGLPGLPGEKGHPGP-----PGLPGNGLPGLPGPRGLPGDKG 637 Query: 340 --GVPGV-GVPGA-GIP---VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 388 G+PG G+PG+ GI ++PG+ G PG PG P+ + + G+ Sbjct: 638 KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT--PGFPGPKGSRGLPGTPGQPGSSGS 695 Query: 389 VGVGGIP--TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 446 G G P + GFPG G G+PG G+PG G+PG+ G PG+ P ++ A Sbjct: 696 KGEPGSPGLVHLPELPGFPG-PRGEKGLPGFPGLPGKDGLPGMIGSPGL---PGSKGATG 751 Query: 447 AKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVA 506 PG G+ G G+ GV PG+ G +PG PG V Sbjct: 752 DIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGT-PGQVG 810 Query: 507 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 566 + + ++ G PG+ G G G PG V G+PG +PG Sbjct: 811 QPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPG 870 Query: 567 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 626 PG++G G+ G G+ G +GP + G VG Sbjct: 871 N-------------PGLVGLKGSPGSPGVAGLPALSGP---------KGEKGSVGFVGFP 908 Query: 627 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAG 671 G+ GL G+PG GL GI P + K G AG G G G Sbjct: 909 GIPGLP----GIPGTRGLKGI-PGSTGKMGPSGRAGTPGEKGDRG 948 Score = 141 bits (356), Expect = 2e-33 Identities = 225/742 (30%), Positives = 279/742 (37%), Gaps = 110/742 (14%) Query: 9 PRPGVLLLLLSILHPSRPG--GVPGAIPG--------GVPGGVFYPGAGLGALGG--GAL 56 P P V + + + PG GVPG +PG G+ G PG L AL G GAL Sbjct: 344 PGPDVFIDIDGAVISGNPGDPGVPG-LPGLKGDEGIQGLRGPSGVPG--LPALSGVPGAL 400 Query: 57 GPGGKP-LKPVPGGLAGAGLGA----GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAG 111 GP G P LK G +GA G P P P + + G Sbjct: 401 GPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG-PPSPEFETETLHNKESGFPG 459 Query: 112 LGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGV 169 L G G G LG+ + G G VP G PG PG P G+ LPG+ Sbjct: 460 LRGEQGPKGNLGLKG--IKGDSGFCACDGGVPNTGPPGE------PGPPGPWGLIGLPGL 511 Query: 170 PTGAGVKPKAPGVGGAF--AGIPG-VGPFGGPQPGVPLGYPIKAP--KLPGGYGLPYTTG 224 G + G GGA AG PG VGP G P G PI + +PG G + G Sbjct: 512 KGARGDR----GSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 567 Query: 225 KLPYGYGPG--GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGV 282 PG GV G G G P G G K G PG+ G G+ Sbjct: 568 FRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP----PGLPGNGL 623 Query: 283 PGVPG--AIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG------ 330 PG+PG +PG G G+ G P + YG + PG PGF Sbjct: 624 PGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG--FPGTPGFPGPKGSR 681 Query: 331 --PGVVGVPGA-------GVPGV-------GVPGA----GIPVVPGAGIPGA-AVPGVV- 368 PG G PG+ G PG+ G PG G+P PG +PG +PG++ Sbjct: 682 GLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG--LPGKDGLPGMIG 739 Query: 369 SPEAAAKAAAKAAKYGARPGV----GVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPG 422 SP A +GA G G+ G+ + +G G PG GV G PG+ G G Sbjct: 740 SPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK-GVHGKPGLLGPKG 798 Query: 423 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV 482 G PG G G +P + K K GL PG PG+ PG G PG Sbjct: 799 ERGSPGTPGQVGQPGTPGSSGPYGIKG-KSGL-PGAPGFPGISGHPGKKGTRGKKGPPGS 856 Query: 483 GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG 542 V G+ PG+ PG PG V K + A L A +G +G VG PG Sbjct: 857 IVKKGL---PGLKGLPG-NPGLVGL--KGSPGSPGVAGLPALSGPKGEKGSVGF-VGFPG 909 Query: 543 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG 601 + G+PG G+PG + K G A PG G G G VGIP Sbjct: 910 IPGLPGIPGTRGLKGIPG--------STGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 961 Query: 602 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAA 661 + A G G G G G G PG+ G G+P + K G Sbjct: 962 MSNLWLKGDKGSQGSAGSNGFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPP 1020 Query: 662 GLGGVLGGAGQFPLGGVAARPG 683 G G+ G G G+ PG Sbjct: 1021 GFMGIRGLPGLKGSSGITGFPG 1042 Score = 128 bits (322), Expect = 2e-29 Identities = 214/777 (27%), Positives = 280/777 (36%), Gaps = 181/777 (23%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K K G+ Sbjct: 50 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYGP-------KGDKGPMGVP 100 Query: 114 GVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 171 G G+ G+ G P+ PG G VG PG P G +PG+ PG+P Sbjct: 101 GFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGPPGLPG 152 Query: 172 GAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QPGVP-- 203 G K P PG+ G G PG VGP G P PG P Sbjct: 153 QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 212 Query: 204 ------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 +G + K LPG G P +TG+L + P G G+ G+ G G+ Sbjct: 213 LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGI 272 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPGIGGIA 296 K G G+ LPG +G GV G PG PG+ G Sbjct: 273 SGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 332 Query: 297 GVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------------AGVPG 343 G+ A ++ G PG PGV G+PG +GVPG Sbjct: 333 GIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGPSGVPG 389 Query: 344 V----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPEAAAKA 376 + GVPGA G P + G AG+PG PG SPE + Sbjct: 390 LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 449 Query: 377 --------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG-VGVG 412 + G + +G+ GG+P G G G PG +G +G+ Sbjct: 450 LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 509 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 472 G+ G G G GG G G PG+ + P + K + L G+ G + G Sbjct: 510 GLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGF 568 Query: 473 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 532 +G PG PG+ PG+ PG G G K G P Sbjct: 569 RGVIG-EPGKDGVPGL---PGLPGLPGDGGQGFPGEKGLPGLPGEKGH--------PGPP 616 Query: 533 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA----LAAAKAAKYG-AAVPGVLGGL 587 GL G G+PGL G+PG G+PG +PG+ L YG + PG G Sbjct: 617 GL-PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFP 675 Query: 588 GALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQF-GLVGAAGLGGL-GVGGL----GVP 639 G G G+PG G G+ + + + G G G GL G GL G+P Sbjct: 676 GPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLP 735 Query: 640 GVGGLGGIPPAAAAKAAKYGA-------------AGLGGVLGGAGQFPLGGVAARPG 683 G+ G G+P + A +GA G G LG +G L GV +PG Sbjct: 736 GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPG 792 Score = 102 bits (254), Expect = 1e-21 Identities = 160/535 (29%), Positives = 199/535 (37%), Gaps = 81/535 (15%) Query: 193 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 246 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 53 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 110 Query: 247 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 302 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 111 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 161 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 359 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 162 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 206 Query: 360 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 417 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 207 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 263 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 264 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 317 Query: 478 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 318 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 373 Query: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 374 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 431 Query: 596 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL-----------GVPGV 641 PG GP + + K + F GL G G G LG+ G+ GVP Sbjct: 432 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 491 Query: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV---AARPGFGLSPIFPGG 693 G PP +G GL G+ G G GG A PG + P+ P G Sbjct: 492 G-----PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 540 Score = 49.7 bits (117), Expect = 9e-06 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 67/303 (22%) Query: 400 GAGGFPG-FGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPG 457 GA G PG G+ G G G G G+ G+ G G PG+ Sbjct: 47 GARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGL---------------------- 84 Query: 458 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVA 516 +G G +GV PG G+ PG PG PG+ G G A Sbjct: 85 LGPYGPKGDKGPMGV-PGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAV------- 133 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 G PG G PGL G+PG G P PG+ K K Sbjct: 134 -------------GFPGPD---GYPGLLGPPGLPGQKGSKGDPVLA--PGSF---KGMKG 172 Query: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GG 635 +PG+ G G G G PG V AGP G +G G GV G Sbjct: 173 DPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGD 232 Query: 636 LGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGAC 695 +G+PG G PP + + G G G G+ G PG P FPG Sbjct: 233 VGLPGPAG----PPPSTGELEFMGFPK--GKKGSKGE---PGPKGFPGISGPPGFPGLGT 283 Query: 696 LGK 698 G+ Sbjct: 284 TGE 286 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 157 bits (396), Expect = 4e-38 Identities = 207/706 (29%), Positives = 264/706 (37%), Gaps = 92/706 (13%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 601 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 656 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVG 145 PG+ P G + K GL G PG G S G +PG+ PG V Sbjct: 657 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKG----EPGS---PGLVHLPE 708 Query: 146 LPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLG 205 LPG PG R G LPG P G K PG+ G+ G+PG G G G Sbjct: 709 LPG------FPGPR--GEKGLPGFP-GLPGKDGLPGMIGS-PGLPGSKGATGDIFGAENG 758 Query: 206 YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAA 264 PG GL TG + G G+ G G G P G G + + + Sbjct: 759 -------APGEQGLQGLTGHKGF-LGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQ 810 Query: 265 KFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLV 323 G++G G +G+PG PG PGI G G GT + K G + Sbjct: 811 PGTPGSSGPYGIKGKSGLPGAPG-FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKG--L 867 Query: 324 PGGPGF--------GPGVVGVPGAGVPG--------VGVPGA-GIPVVPGA-GIPGAAVP 365 PG PG PGV G+P P VG PG G+P +PG G+ G +P Sbjct: 868 PGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKG--IP 925 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY-----------------GVGAGGFPGFG 408 G + A + G R G GIP+ G+ GFPG Sbjct: 926 GSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPG-- 983 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAP 468 G G AG PG G+PG G+PG+ + GL PG+ + G+ P Sbjct: 984 --PRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITGFP 1040 Query: 469 GVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG 528 G+ PG + G+ +PG+ PG PG+ G + + K Q + G Sbjct: 1041 GM---PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGFKG 1093 Query: 529 A-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 587 G GL +G PG G G+ G+PG PG A + G +PG G Sbjct: 1094 TKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSGHQ 1149 Query: 588 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGLGG 646 GA+G +G PG + G G G G GV G G+PG G G Sbjct: 1150 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1209 Query: 647 IPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 P K G G G G G G+ PG L + G Sbjct: 1210 YPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAG 1255 Score = 155 bits (392), Expect = 1e-37 Identities = 227/782 (29%), Positives = 299/782 (38%), Gaps = 175/782 (22%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 725 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVS 124 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 785 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 840 Query: 125 AGAVVPQ-----PGAGVKPGKVPGV-GLPGVYPGGV-LPGARFPGVGVLPGVPTGAGVKP 177 G + PG+ VK G +PG+ GLPG PG V L G+ PG + G+P +G K Sbjct: 841 PGKKGTRGKKGPPGSIVKKG-LPGLKGLPG-NPGLVGLKGS--PGSPGVAGLPALSGPKG 896 Query: 178 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 + VG F G PG+ PG+P P G G+P +TGK+ GP G AG Sbjct: 897 EKGSVG--FVGFPGI-------PGLP-----GIPGTRGLKGIPGSTGKM----GPSGRAG 938 Query: 238 AAGKAG---YPTGTGV----------------GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 G+ G P G+ G Q +A + + G AG G Sbjct: 939 TPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPG 998 Query: 279 GAGVPGVPGAIPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFG 330 G PG+PG I G+ G G G P ++ G + + G PG Sbjct: 999 LPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGL- 1057 Query: 331 PGVVGVPG-----------AGVPG----------------------VGVPG-----AGIP 352 PG G+PG +G PG +G PG + Sbjct: 1058 PGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVG 1117 Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV- 409 V G+PGA PGV + GA +G G+ +G GFPGF G+ Sbjct: 1118 VSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL----IGPKGFPGFPGLH 1173 Query: 410 GVGGIPG-----------VAGVPGVGGVPGVGG---VPGVGISPEAQAAAAAKAAKYGLV 455 G+ G+PG + GVPG G+PG G PG+GI + + G Sbjct: 1174 GLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGF- 1232 Query: 456 PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAK 514 PG+ G+ APG+ + + PG PG+ G PG GP G + + Sbjct: 1233 PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG---RPGPAGPPGPPGPSSNQGD 1289 Query: 515 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPG-LGVGA--GVPGFGAVPGALAAA 571 GIPG G G+ +G+PG LG+ G PGF PG + Sbjct: 1290 TGDPGF--------PGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPP 1341 Query: 572 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 631 + PG+ G G G G+ G P A GL G G+ GL Sbjct: 1342 GDPGF----PGMKGKAGPRGSSGLQGD-----PGQTPTAEAVQVPPGPLGLPGIDGIPGL 1392 Query: 632 -----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGL 686 G +G+ G GL GIP K G +GL G G G L G+ PGF Sbjct: 1393 TGDPGAQGPVGLQGSKGLPGIP-------GKDGPSGLPGPPGALGDPGLPGLQGPPGFEG 1445 Query: 687 SP 688 +P Sbjct: 1446 AP 1447 Score = 149 bits (375), Expect = 1e-35 Identities = 232/799 (29%), Positives = 290/799 (36%), Gaps = 173/799 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 181 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 240 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 241 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 296 Query: 115 VPGVGGLGVSAGAVVPQPGAGVKPGKV--PG-------------VGLPGV-----YPGGV 154 +PG G S G P PG K G + PG +GLPG G V Sbjct: 297 LPGPRGPMGSEGVQGP-PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV 355 Query: 155 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 204 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 356 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 415 Query: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 252 I A LPG GLP GP G G ++G+P G GP Sbjct: 416 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 465 Query: 253 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 297 + K + F A GV P G G PG PG +PG+ G G Sbjct: 466 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 524 Query: 298 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 345 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 525 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 584 Query: 346 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 386 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 585 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 644 Query: 387 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 435 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 645 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 703 Query: 436 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV--------GVAPG 487 PE + K GL PG PG PG+ +PG+ + G APG Sbjct: 704 VHLPELPGFPGPRGEK-GL-PGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPG 761 Query: 488 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 546 G+ G +G G+ V K L G G PG VG PG Sbjct: 762 EQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPGTPGQVGQPGTPGS 816 Query: 547 AGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 604 +G G+ +G+PG PG K + PG + G G G+PG G Sbjct: 817 SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 876 Query: 605 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLG 664 + + A A G G G VG +G PG+ GL GIP G GL Sbjct: 877 KGSPGSPGVAGLPALSGPKGEKG----SVGFVGFPGIPGLPGIP----------GTRGLK 922 Query: 665 GVLGGAGQFPLGGVAARPG 683 G+ G G+ G A PG Sbjct: 923 GIPGSTGKMGPSGRAGTPG 941 Score = 141 bits (356), Expect = 2e-33 Identities = 204/705 (28%), Positives = 271/705 (38%), Gaps = 119/705 (16%) Query: 36 GVPGGVFYPGAGLGALGG-GALGPGGKPLKP----VPG-----GLAGAGLGAGL-GAFPA 84 G+PG PG G +G G GP G+ K PG G+ G GL G Sbjct: 293 GIPG---LPGPR-GPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVF 348 Query: 85 VTFPGALVPGGVADAAAAYKAAKAG-------AGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 + GA++ G D G G GVPG+ L GA+ PQ G+K Sbjct: 349 IDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLK 408 Query: 138 -----PGK-------VPGV-GLPGVY--PGGVLPG----------ARFPGVGVLPGVPTG 172 PG+ +PG GLPG PG P + FPG+ G Sbjct: 409 GDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGN 468 Query: 173 AGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK----- 225 G+K G G+P GP G P P P G I P L G G + G Sbjct: 469 LGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGL-IGLPGLKGARGDRGSGGAQGPAG 527 Query: 226 LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 P GP G +G GK G P + + Q + ++ G GV+ G GVPG+ Sbjct: 528 APGLVGPLGPSGPKGKKGEPILSTI--QGMPGDRGDSGSQ---GFRGVIGEPGKDGVPGL 582 Query: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG----PGVVGVPGA-- 339 PG +PG+ G G G P + G PG PG G PG G+PG Sbjct: 583 PG-LPGLPGDGGQGFPGEKGLPGLPGEKGHPGP-----PGLPGNGLPGLPGPRGLPGDKG 636 Query: 340 --GVPGV-GVPGA-GIP---VVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPG 388 G+PG G+PG+ GI ++PG+ G PG PG P+ + + G+ Sbjct: 637 KDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT--PGFPGPKGSRGLPGTPGQPGSSGS 694 Query: 389 VGVGGIP--TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 446 G G P + GFPG G G+PG G+PG G+PG+ G PG+ P ++ A Sbjct: 695 KGEPGSPGLVHLPELPGFPG-PRGEKGLPGFPGLPGKDGLPGMIGSPGL---PGSKGATG 750 Query: 447 AKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVA 506 PG G+ G G+ GV PG+ G +PG PG V Sbjct: 751 DIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGT-PGQVG 809 Query: 507 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 566 + + ++ G PG+ G G G PG V G+PG +PG Sbjct: 810 QPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPG 869 Query: 567 ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAA 626 PG++G G+ G G+ G +GP + G VG Sbjct: 870 N-------------PGLVGLKGSPGSPGVAGLPALSGP---------KGEKGSVGFVGFP 907 Query: 627 GLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAG 671 G+ GL G+PG GL GI P + K G AG G G G Sbjct: 908 GIPGLP----GIPGTRGLKGI-PGSTGKMGPSGRAGTPGEKGDRG 947 Score = 141 bits (356), Expect = 2e-33 Identities = 225/742 (30%), Positives = 279/742 (37%), Gaps = 110/742 (14%) Query: 9 PRPGVLLLLLSILHPSRPG--GVPGAIPG--------GVPGGVFYPGAGLGALGG--GAL 56 P P V + + + PG GVPG +PG G+ G PG L AL G GAL Sbjct: 343 PGPDVFIDIDGAVISGNPGDPGVPG-LPGLKGDEGIQGLRGPSGVPG--LPALSGVPGAL 399 Query: 57 GPGGKP-LKPVPGGLAGAGLGA----GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAG 111 GP G P LK G +GA G P P P + + G Sbjct: 400 GPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPG-PPSPEFETETLHNKESGFPG 458 Query: 112 LGGVPGV-GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGV 169 L G G G LG+ + G G VP G PG PG P G+ LPG+ Sbjct: 459 LRGEQGPKGNLGLKG--IKGDSGFCACDGGVPNTGPPGE------PGPPGPWGLIGLPGL 510 Query: 170 PTGAGVKPKAPGVGGAF--AGIPG-VGPFGGPQPGVPLGYPIKAP--KLPGGYGLPYTTG 224 G + G GGA AG PG VGP G P G PI + +PG G + G Sbjct: 511 KGARGDR----GSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 566 Query: 225 KLPYGYGPG--GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGV 282 PG GV G G G P G G K G PG+ G G+ Sbjct: 567 FRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGP----PGLPGNGL 622 Query: 283 PGVPG--AIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG------ 330 PG+PG +PG G G+ G P + YG + PG PGF Sbjct: 623 PGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSG--FPGTPGFPGPKGSR 680 Query: 331 --PGVVGVPGA-------GVPGV-------GVPGA----GIPVVPGAGIPGA-AVPGVV- 368 PG G PG+ G PG+ G PG G+P PG +PG +PG++ Sbjct: 681 GLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPG--LPGKDGLPGMIG 738 Query: 369 SPEAAAKAAAKAAKYGARPGV----GVGGIPTYG--VGAGGFPGFGVGVGGIPGVAGVPG 422 SP A +GA G G+ G+ + +G G PG GV G PG+ G G Sbjct: 739 SPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK-GVHGKPGLLGPKG 797 Query: 423 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV 482 G PG G G +P + K K GL PG PG+ PG G PG Sbjct: 798 ERGSPGTPGQVGQPGTPGSSGPYGIKG-KSGL-PGAPGFPGISGHPGKKGTRGKKGPPGS 855 Query: 483 GVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG 542 V G+ PG+ PG PG V K + A L A +G +G VG PG Sbjct: 856 IVKKGL---PGLKGLPG-NPGLVGL--KGSPGSPGVAGLPALSGPKGEKGSVGF-VGFPG 908 Query: 543 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIPGGVVG 601 + G+PG G+PG + K G A PG G G G VGIP Sbjct: 909 IPGLPGIPGTRGLKGIPG--------STGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRP 960 Query: 602 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAA 661 + A G G G G G G PG+ G G+P + K G Sbjct: 961 MSNLWLKGDKGSQGSAGSNGFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPP 1019 Query: 662 GLGGVLGGAGQFPLGGVAARPG 683 G G+ G G G+ PG Sbjct: 1020 GFMGIRGLPGLKGSSGITGFPG 1041 Score = 128 bits (322), Expect = 2e-29 Identities = 214/777 (27%), Positives = 280/777 (36%), Gaps = 181/777 (23%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K K G+ Sbjct: 49 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYGP-------KGDKGPMGVP 99 Query: 114 GVPGVGGLGVSAGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 171 G G+ G+ G P+ PG G VG PG P G +PG+ PG+P Sbjct: 100 GFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGPPGLPG 151 Query: 172 GAGVK----------------PKAPGVGG-----AFAGIPG-VGPFGGP----QPGVP-- 203 G K P PG+ G G PG VGP G P PG P Sbjct: 152 QKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGP 211 Query: 204 ------LGYPIKAPK-------LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 +G + K LPG G P +TG+L + P G G+ G+ G G+ Sbjct: 212 LGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGI 271 Query: 251 GPQAAAAAAAKAAAKFGAGAAGV--LPG----VGGAGVPGVPG--------AIPGIGGIA 296 K G G+ LPG +G GV G PG PG+ G Sbjct: 272 SGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQ 331 Query: 297 GVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------------AGVPG 343 G+ A ++ G PG PGV G+PG +GVPG Sbjct: 332 GIEGQKGDIGLPGPDVFIDIDGA--VISGNPG-DPGVPGLPGLKGDEGIQGLRGPSGVPG 388 Query: 344 V----GVPGA----GIPVVPG------------AGIPG-------AAVPGVVSPEAAAKA 376 + GVPGA G P + G AG+PG PG SPE + Sbjct: 389 LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 448 Query: 377 --------AAKAAKYGARPGVGV-------------GGIPTYG-VGAGGFPG-FG-VGVG 412 + G + +G+ GG+P G G G PG +G +G+ Sbjct: 449 LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 508 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 472 G+ G G G GG G G PG+ + P + K + L G+ G + G Sbjct: 509 GLKGARGDRGSGGAQGPAGAPGL-VGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGF 567 Query: 473 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 532 +G PG PG+ PG+ PG G G K G P Sbjct: 568 RGVIG-EPGKDGVPGL---PGLPGLPGDGGQGFPGEKGLPGLPGEKGH--------PGPP 615 Query: 533 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA----LAAAKAAKYG-AAVPGVLGGL 587 GL G G+PGL G+PG G+PG +PG+ L YG + PG G Sbjct: 616 GL-PGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFP 674 Query: 588 GALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQF-GLVGAAGLGGL-GVGGL----GVP 639 G G G+PG G G+ + + + G G G GL G GL G+P Sbjct: 675 GPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLP 734 Query: 640 GVGGLGGIPPAAAAKAAKYGA-------------AGLGGVLGGAGQFPLGGVAARPG 683 G+ G G+P + A +GA G G LG +G L GV +PG Sbjct: 735 GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPG 791 Score = 102 bits (254), Expect = 1e-21 Identities = 160/535 (29%), Positives = 199/535 (37%), Gaps = 81/535 (15%) Query: 193 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 246 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 52 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 109 Query: 247 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 302 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 110 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 160 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 359 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 161 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 205 Query: 360 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 417 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 206 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 262 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 263 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 316 Query: 478 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 317 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 372 Query: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 373 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 430 Query: 596 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL-----------GVPGV 641 PG GP + + K + F GL G G G LG+ G+ GVP Sbjct: 431 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 490 Query: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGV---AARPGFGLSPIFPGG 693 G PP +G GL G+ G G GG A PG + P+ P G Sbjct: 491 G-----PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 539 Score = 49.7 bits (117), Expect = 9e-06 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 67/303 (22%) Query: 400 GAGGFPG-FGV-GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPG 457 GA G PG G+ G G G G G+ G+ G G PG+ Sbjct: 46 GARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGL---------------------- 83 Query: 458 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVA 516 +G G +GV PG G+ PG PG PG+ G G A Sbjct: 84 LGPYGPKGDKGPMGV-PGF---LGINGIPGHPGQPGPRGPPGLDGCNGTQGAV------- 132 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 G PG G PGL G+PG G P PG+ K K Sbjct: 133 -------------GFPGPD---GYPGLLGPPGLPGQKGSKGDPVLA--PGSF---KGMKG 171 Query: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GG 635 +PG+ G G G G PG V AGP G +G G GV G Sbjct: 172 DPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGD 231 Query: 636 LGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGAC 695 +G+PG G PP + + G G G G+ G PG P FPG Sbjct: 232 VGLPGPAG----PPPSTGELEFMGFPK--GKKGSKGE---PGPKGFPGISGPPGFPGLGT 282 Query: 696 LGK 698 G+ Sbjct: 283 TGE 285 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 154 bits (388), Expect = 4e-37 Identities = 210/668 (31%), Positives = 245/668 (36%), Gaps = 159/668 (23%) Query: 52 GGGALGPGG----KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 GGGA G G K ++P+ G G G G + + P L+P + K Sbjct: 29 GGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLP--LLPMDL----------K 76 Query: 108 AGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVLPGARFPGV 163 G G PG G PG PGK PG+G PG++ P G PG G Sbjct: 77 GEPGPPGKPGPRG----------PPGPPGFPGK-PGMGKPGLHGQPGPAGP-PGFSRMGK 124 Query: 164 GVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPY 221 PG+P G P PG+ G GI G GP PG+P I P PG G+P Sbjct: 125 AGPPGLPGKVG-PPGQPGLRGE-PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVP- 181 Query: 222 TTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 281 GP G G G G P GP G G G LPG G G Sbjct: 182 ---------GPPGFQGEPGPQGEP-----GPPGDRGLKGDN----GVGQPG-LPGAPGQG 222 Query: 282 VPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-G 340 G PG PG+ G AG+G P A + G VPG G PG VG G G Sbjct: 223 --GAPGP-PGLPGPAGLGKPGLDGLPGAPGDKGESGPPG--VPGPRG-EPGAVGPKGPPG 276 Query: 341 VPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 V GVGVPGA AG+PG P GA+ G G P +G Sbjct: 277 VDGVGVPGA-------AGLPGPQGPS-----------------GAKGEPGTRGPPGL-IG 311 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAAAAAKAAKYGLVPG 457 G+ G+ G+PG G G GVPG+ G PG P Q G Sbjct: 312 PTGY-----GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQ-----------G 355 Query: 458 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVA 516 +G PG+ PG PG PG G G PGV G+ GP G+A Sbjct: 356 LGGPPGL---PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA---------- 402 Query: 517 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 576 G PG+ G+PG G PG G PGF PG Sbjct: 403 -------------GKPGVPGERGLPG---AHGPPGPTGPKGEPGFTGRPGG--------- 437 Query: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----G 632 PGV G LG G +G+PG GP+ A GL G G GL G Sbjct: 438 ----PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPG 493 Query: 633 VGGLGVPGVGGLGGIP--PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIF 690 G G PG G G P P + G G G G G F G+A G L Sbjct: 494 EGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIA---GLHLPNGG 550 Query: 691 PGGACLGK 698 GA LGK Sbjct: 551 VEGAVLGK 558 Score = 137 bits (346), Expect = 3e-32 Identities = 175/538 (32%), Positives = 211/538 (39%), Gaps = 71/538 (13%) Query: 15 LLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALG-GGALGPGGKPLKPVPGGLAG 72 LL + + P G PG P G PG +PG G+G G G GP G P G + Sbjct: 70 LLPMDLKGEPGPPGKPG--PRGPPGPPGFPGKPGMGKPGLHGQPGPAGPP------GFSR 121 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVP-Q 131 G G PG + P G + GL G PG GL +G +P + Sbjct: 122 MGKAGPPG------LPGKVGPPG-QPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGK 174 Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARF----PGVGV--LPGVPTGAGVKPKAPGVGG- 184 PGA PG G PG PG R GVG LPG P G G P PG+ G Sbjct: 175 PGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAP-GQGGAPGPPGLPGP 233 Query: 185 ------AFAGIPGV-------GPFGGPQP-GVPLGYPIKAPKLPGGYGLPYTTGKLPYGY 230 G+PG GP G P P G P K P G G+P G LP Sbjct: 234 AGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAG-LPGPQ 292 Query: 231 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 290 GP G G G G P G +GP K G AGV +G G PG G P Sbjct: 293 GPSGAKGEPGTRG-PPGL-IGPTGYGMPGLPGP-KGDRGPAGVPGLLGDRGEPGEDGE-P 348 Query: 291 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAG 350 G G G+G P +A + G GPG PGV G+ G P G+ AG Sbjct: 349 GEQGPQGLGGPPGLPGSAGLP--GRRGPPGPKGEAGPGGPPGVPGIRGDQGPS-GL--AG 403 Query: 351 IPVVPGA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 408 P VPG G+PGA PG P+ + G +G G +G G PG Sbjct: 404 KPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKG----DLGLPGQPGLR 459 Query: 409 --VGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGVAPGVG 465 G+ G+ G AG G G+PG+ G PG+ G E +A A G PGV +PG+ Sbjct: 460 GPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTG-PPGVPGSPGIT 518 Query: 466 VAPGVGVAPGVGLAPGVGVAPGV-----------GVAPGVGVAPGIGPGGVAAAAKSA 512 PG PG APG G+ G G G P G G ++A A A Sbjct: 519 GPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPA 576 Score = 64.3 bits (155), Expect = 4e-10 Identities = 84/261 (32%), Positives = 103/261 (39%), Gaps = 33/261 (12%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G+ G P G+PG PG G GPGG P P G+ G +GL P V Sbjct: 353 PQGLGG--PPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVP---GIRGDQGPSGLAGKPGV 407 Query: 86 T----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV--KPG 139 PGA P G K G G PG G+ AGA+ + G+ +PG Sbjct: 408 PGERGLPGAHGPPGPT-------GPKGEPGFTGRPGGPGV---AGALGQKGDLGLPGQPG 457 Query: 140 KVPGVGLPGVY-PGGVLPGARFPGVGVLPGVPTGAGV-KPKAPGVGGAFA--GIPGVGPF 195 G+PG+ P G + PG+ PG+P G + PG G G+PG Sbjct: 458 LRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGI 517 Query: 196 GGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA-GKAGYPTGTGVGPQA 254 GP PG P P PG G TG GGV GA GK G P G+G + Sbjct: 518 TGP-PGPP-----GPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQ-FGLGELS 570 Query: 255 AAAAAAKAAAKFGAGAAGVLP 275 A A A A A +P Sbjct: 571 AHATPAFTAVLTSPFPASGMP 591 Score = 37.7 bits (86), Expect = 0.037 Identities = 36/120 (30%), Positives = 44/120 (36%), Gaps = 8/120 (6%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKP----LKPVPGGLAGAGLG 76 P P G+PG G PG PG G G G GP G P + PG G Sbjct: 473 PIGPQGLPGL--KGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPP 530 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGV 136 GAF G +P G + A K K GLG + +A P P +G+ Sbjct: 531 GAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPAFTAVLTSPFPASGM 590 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 151 bits (382), Expect = 2e-36 Identities = 183/568 (32%), Positives = 212/568 (37%), Gaps = 133/568 (23%) Query: 131 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 185 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 241 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 242 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 301 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 302 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 358 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 416 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 476 G PG+GG PG G+PG+ A K G G G PG PG+ Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPK-----GEGGIVGPQGPPGPKGEPGL 433 Query: 477 GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 PG G PG+ PG IGP G A G+PGL Sbjct: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ--------------------KGVPGL- 472 Query: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 GVPGL G PG+ G G PG +PG+ G G +G GI Sbjct: 473 --PGVPGLLGPKGEPGI---PGDQGLQGPPG-------------IPGIGGPSGPIGPPGI 514 Query: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGLGVPGVGGLGGIPPAAAAK 654 PG G GL G G G+G PGV GL G PP Sbjct: 515 PGP------------------------KGEPGLPGPPGFPGIGKPGVAGLHG-PPGKPGA 549 Query: 655 AAKYGAAGLGGVLGGAGQFPLGGVAARP 682 G GL G G G P G A P Sbjct: 550 LGPQGQPGLPGPPGPPG--PPGPPAVMP 575 Score = 134 bits (338), Expect = 2e-31 Identities = 176/515 (34%), Positives = 214/515 (41%), Gaps = 86/515 (16%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGVGGLGVSAGAVVPQPGAGVKPGK------VPGV-GLPGVY--PGGV-LPGARFPGVGV 165 PG G G PQ G K K PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 166 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 222 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 223 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 278 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 279 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGFGPG 332 G G PG+PG IPG G G +G P G GL PG PGF G Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF-LG 444 Query: 333 VVGVPGA-GVPG-VGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 389 VG PG G+PG +G G AG VPG +PG VPG++ P+ G PG+ Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPG--LPG--VPGLLGPKGEPGIPGDQGLQGP-PGI 499 Query: 390 -GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG-----------------------G 425 G+GG P+ +G G PG G G+PG G PG+G G Sbjct: 500 PGIGG-PSGPIGPPGIPG-PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 460 +PG G PG P +Y G+G+ Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Score = 134 bits (336), Expect = 4e-31 Identities = 174/569 (30%), Positives = 209/569 (36%), Gaps = 119/569 (20%) Query: 174 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 227 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 228 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 343 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 459 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 460 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 519 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 520 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 578 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 579 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 619 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 620 FGLVGAAGLGGL-------------GVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAAGL 663 G VG G+ GL GV GL GVPG+ G G P P G G+ Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502 Query: 664 GGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 GG G G + G PG P FPG Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 108 bits (269), Expect = 2e-23 Identities = 136/410 (33%), Positives = 159/410 (38%), Gaps = 71/410 (17%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G P + PG +PG + K GL G+PG GL P P Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 191 G VPG P G + GA PG+G PG P G+ P G GA G PG Sbjct: 361 DRGMGGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKG 414 Query: 192 ----VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 VGP G P P G P G+P K P G G P G LP GP G AG G G Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGL 472 Query: 245 PTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGV 298 P G+ GP+ + G G+ G G PG+PG +PG G G+ Sbjct: 473 PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI 532 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP- 355 G P A K PG GP PG+ G PG PG P A +P P Sbjct: 533 GKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPP 579 Query: 356 --GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 G +P G + GV P A YGA+ G G P Y + A Sbjct: 580 PQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 Score = 44.7 bits (104), Expect = 3e-04 Identities = 69/221 (31%), Positives = 80/221 (36%), Gaps = 55/221 (24%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGG 60 AG PGV LL P PG P G+PG G G +G G GP G Sbjct: 464 AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG----IGGPSGPIGPPGIPGPKG 519 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 +P P P G FP + PG AGL G PG Sbjct: 520 EPGLPGPPG------------FPGIGKPGV-------------------AGLHGPPG--- 545 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKA 179 GA+ PQ G+ PG G PG P V+P P LP + G GVKP Sbjct: 546 ---KPGALGPQGQPGL-PGPPGPPGPPG--PPAVMPPTPPPQGEYLPDMGLGIDGVKP-- 597 Query: 180 PGVGGAFAGIPGVGPFGGP-------QPGVPLGYPIKAPKL 213 P GA G G + P P P+G P+K KL Sbjct: 598 PHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKL 638 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 151 bits (382), Expect = 2e-36 Identities = 183/568 (32%), Positives = 212/568 (37%), Gaps = 133/568 (23%) Query: 131 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 184 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 185 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 241 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 242 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 301 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 302 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 358 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 416 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 417 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 476 G PG+GG PG G+PG+ A K G G G PG PG+ Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPK-----GEGGIVGPQGPPGPKGEPGL 433 Query: 477 GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 PG G PG+ PG IGP G A G+PGL Sbjct: 434 QGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQ--------------------KGVPGL- 472 Query: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 GVPGL G PG+ G G PG +PG+ G G +G GI Sbjct: 473 --PGVPGLLGPKGEPGI---PGDQGLQGPPG-------------IPGIGGPSGPIGPPGI 514 Query: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGLGVPGVGGLGGIPPAAAAK 654 PG G GL G G G+G PGV GL G PP Sbjct: 515 PGP------------------------KGEPGLPGPPGFPGIGKPGVAGLHG-PPGKPGA 549 Query: 655 AAKYGAAGLGGVLGGAGQFPLGGVAARP 682 G GL G G G P G A P Sbjct: 550 LGPQGQPGLPGPPGPPG--PPGPPAVMP 575 Score = 134 bits (338), Expect = 2e-31 Identities = 176/515 (34%), Positives = 214/515 (41%), Gaps = 86/515 (16%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGVGGLGVSAGAVVPQPGAGVKPGK------VPGV-GLPGVY--PGGV-LPGARFPGVGV 165 PG G G PQ G K K PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 166 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 222 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 223 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 278 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 279 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGFGPG 332 G G PG+PG IPG G G +G P G GL PG PGF G Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF-LG 444 Query: 333 VVGVPGA-GVPG-VGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 389 VG PG G+PG +G G AG VPG +PG VPG++ P+ G PG+ Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPG--LPG--VPGLLGPKGEPGIPGDQGLQGP-PGI 499 Query: 390 -GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG-----------------------G 425 G+GG P+ +G G PG G G+PG G PG+G G Sbjct: 500 PGIGG-PSGPIGPPGIPG-PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 460 +PG G PG P +Y G+G+ Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Score = 134 bits (336), Expect = 4e-31 Identities = 174/569 (30%), Positives = 209/569 (36%), Gaps = 119/569 (20%) Query: 174 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 227 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 228 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 343 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 400 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 459 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 460 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 519 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 520 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 578 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 579 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 619 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 620 FGLVGAAGLGGL-------------GVGGL-GVPGVGGLGGIP--PAAAAKAAKYGAAGL 663 G VG G+ GL GV GL GVPG+ G G P P G G+ Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGI 502 Query: 664 GGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 GG G G + G PG P FPG Sbjct: 503 GGPSGPIGPPGIPGPKGEPGLPGPPGFPG 531 Score = 108 bits (269), Expect = 2e-23 Identities = 136/410 (33%), Positives = 159/410 (38%), Gaps = 71/410 (17%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G P + PG +PG + K GL G+PG GL P P Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKG 360 Query: 135 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 191 G VPG P G + GA PG+G PG P G+ P G GA G PG Sbjct: 361 DRGMGGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GFPGPKG 414 Query: 192 ----VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 244 VGP G P P G P G+P K P G G P G LP GP G AG G G Sbjct: 415 EGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQKGVPGL 472 Query: 245 PTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGV 298 P G+ GP+ + G G+ G G PG+PG +PG G G+ Sbjct: 473 PGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI 532 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGIPVVP- 355 G P A K PG GP PG+ G PG PG P A +P P Sbjct: 533 GKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVMPPTPP 579 Query: 356 --GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 G +P G + GV P A YGA+ G G P Y + A Sbjct: 580 PQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 Score = 44.7 bits (104), Expect = 3e-04 Identities = 69/221 (31%), Positives = 80/221 (36%), Gaps = 55/221 (24%) Query: 2 AGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGG 60 AG PGV LL P PG P G+PG G G +G G GP G Sbjct: 464 AGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPG----IGGPSGPIGPPGIPGPKG 519 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 +P P P G FP + PG AGL G PG Sbjct: 520 EPGLPGPPG------------FPGIGKPGV-------------------AGLHGPPG--- 545 Query: 121 LGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKA 179 GA+ PQ G+ PG G PG P V+P P LP + G GVKP Sbjct: 546 ---KPGALGPQGQPGL-PGPPGPPGPPG--PPAVMPPTPPPQGEYLPDMGLGIDGVKP-- 597 Query: 180 PGVGGAFAGIPGVGPFGGP-------QPGVPLGYPIKAPKL 213 P GA G G + P P P+G P+K KL Sbjct: 598 PHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKL 638 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 146 bits (369), Expect = 6e-35 Identities = 236/784 (30%), Positives = 280/784 (35%), Gaps = 156/784 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGA-GLGA-- 77 P PG G PG + PG L G G GP G P P P G GA GL Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPG-----LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGER 592 Query: 78 ------------GLGAFPA----VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 GL FP G P GVA + K G G PGV G Sbjct: 593 GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP----QGEKGDVGPAGPPGVPGS 648 Query: 122 GVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPK-- 178 V + + GA PG G PG PGAR P G G P G++ K Sbjct: 649 VVQQEGLKGEQGA---PGPRGHQGAPGP------PGARGPIGPEGRDGPPGLQGLRGKKG 699 Query: 179 ---APGVGGAFA-----GIPGV-GPFG-GPQPGVP--LGYPIKAPKLPGGYGLPYTTGK- 225 PG+ G G PGV GP G G PG+P +G+P K P PG G P G Sbjct: 700 DMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK-PGPPGPTGPPGKDGPN 758 Query: 226 -LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV--LPGV---- 277 P G G G G+ G P G+ G A + K AG G PGV Sbjct: 759 GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEK 818 Query: 278 ------GGAGVPGV-----------PGAIPGIGGIAGVGTPAAAAAAAAAAKAAK----- 315 G G+PG+ P PG+ G + TP K K Sbjct: 819 GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 878 Query: 316 ------YGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPG-AGIPG-AAVPG 366 G L P GP PG G GA G PG AG P PG G PG + PG Sbjct: 879 PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG----AAGNPGAPGHVGAPGPSGPPG 934 Query: 367 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG-- 424 V K + G + G G P VG G P G PG+ G PG G Sbjct: 935 SVGAPGLRGTPGKDGERGEKGAAGEEGSPG-PVGPRGDP-------GAPGLPGPPGKGKD 986 Query: 425 GVPGVGGVPGVGISPEAQAAAAAK-------AAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G PG+ G PG+ P AA K A V G APG+ +PG PG+G Sbjct: 987 GEPGLRGSPGLP-GPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIG 1045 Query: 478 LA--PGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAK--VAAKAQLRAAAGLG- 528 +A PG PG +PG PG GP G A + + K L + G Sbjct: 1046 VAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105 Query: 529 -------------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA 569 G+PG GVPG G G AG PG PG +A Sbjct: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IA 1164 Query: 570 AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL- 628 + ++ G +G G G G+PG + G A A A G+ G+ G Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224 Query: 629 ---GGLGVGGL-GVPGVGGLGGI-----PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 679 G G GL G+PG G G PP KA + G G G G G G + Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284 Query: 680 ARPG 683 PG Sbjct: 1285 GAPG 1288 Score = 119 bits (298), Expect = 1e-26 Identities = 194/653 (29%), Positives = 236/653 (36%), Gaps = 106/653 (16%) Query: 107 KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 166 K G+ G G+ G GA+ P G K K G G+ P G +G L Sbjct: 483 KGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEK----GDVGIGPFGQGEKGEKGSLG-L 537 Query: 167 PGVPTGAGVKPKA--PGVGGAFAGIPGVGPFGGPQ--PGVPLGYP--IKAPKLPGGYGLP 220 PG P G K PG G G+PG GPQ PG+P G P + AP L G G Sbjct: 538 PGPPGRDGSKGMRGEPGELGE-PGLPGEVGMRGPQGPPGLP-GPPGRVGAPGLQGERGEK 595 Query: 221 YTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA 280 T G+ G G+ G GK G TG P + A G G VG A Sbjct: 596 GTRGEK----GERGLDGFPGKPG-DTGQQGRPGPSGVA----------GPQGEKGDVGPA 640 Query: 281 GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG- 338 G PGVPG++ G+ G G P A GA + P G PG+ G+ G Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPP---GARGPIGPEGRDGPPGLQGLRGK 697 Query: 339 ------AGVPGV----GVPG-AGIPVVPG----AGIPG-AAVPGVVSPEAAAKAAAKAAK 382 G+PG+ G PG G+P PG G+PG PG P K Sbjct: 698 KGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGP 757 Query: 383 YGARPGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 437 G G G P G G PG +G G+ G G G G+PG G PGV Sbjct: 758 NGPPGPPGTKGEPGER-GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGV-- 814 Query: 438 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV----------GLAPGVGVAPG 487 + + + GL PG+ G G PG+ PG G Sbjct: 815 --RGEKGDQGEKGELGL-PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871 Query: 488 VGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV 545 PG+ PG+ G G AK Q A G AG PG VG PG Sbjct: 872 EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG--- 928 Query: 546 GAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG------ 597 +G PG G PG PG K A PG +G G G G+PG Sbjct: 929 PSGPPG---SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGK 985 Query: 598 ----GVVGA----GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-------GVPGVG 642 G+ G+ GP AA + L G G G G+ G PG+G Sbjct: 986 DGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIG 1045 Query: 643 GLGGIPPAAAAKAAKYGAAGLGGVLGGAG-QFPLG--GVAARPGFGLSPIFPG 692 G PP + G+ G G+ G G Q P G G PG P PG Sbjct: 1046 VAG--PPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096 Score = 112 bits (280), Expect = 1e-24 Identities = 211/757 (27%), Positives = 248/757 (32%), Gaps = 141/757 (18%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPG-----------AGLGALGG----GALGPGGKPLKPV 66 +P PG V P G PG V PG GA G G +GP G P P Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGALVPG-------GVADAAAAYKAAKAGAGLGGVPGVG 119 G G G G + PG L G + A + K G G+PG Sbjct: 977 LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036 Query: 120 GLGVSAG-AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK 178 G G V PG PG G G LPG FPG P P G P Sbjct: 1037 GSRGDPGIGVAGPPGPSGPPGDKGSPGSRG------LPG--FPG----PQGPAGRDGAPG 1084 Query: 179 APGVGGAFAGIPGVGPFGGPQP----------GVPLGYPIKAPKLPGGYGLPYTTGKLPY 228 PG G G PG+ P P G P P LPG G GK P Sbjct: 1085 NPGERGP-PGKPGLSSLLSPGDINLLAKDVCNDCPPGPP-GLPGLPGFKGDKGVPGK-PG 1141 Query: 229 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPG 287 G G G AG G P G+ + A + G PGV G G PG PG Sbjct: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201 Query: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPG-----------GPGFGPGVV 334 PG GIAG P + +GL +PG GP PG Sbjct: 1202 P-PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260 Query: 335 GVPGA-------GVPGV-------GVPG----AGIPVVPGA-GIPG----AAVPGVVSPE 371 G PG G PG G PG +G +PG G+PG G P+ Sbjct: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAG-----GFPGF--GVGVGGIPGVAGVPGVG 424 K G+ G G P G G PGF G G PG GVPG Sbjct: 1321 GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380 Query: 425 GVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 484 GVPG G PG K PG PG PG G+ G+ Sbjct: 1381 GVPGKPGEPGFKGERGDPGIKGDKGP-----PGGKGQPGDPGIPGHKGHTGLMGPQGLPG 1435 Query: 485 APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLG 544 G PG PG G+ + S + Q L + L + + Sbjct: 1436 ENGPVGPPGPPGQPGF--PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493 Query: 545 VGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 604 G PG G PG +PG +A G PG G GG+ P G +G Sbjct: 1494 SSQGRPG---PPGPPGKDGLPG-----RAGPMGE--PGRPG----QGGLEGPSGPIG--- 1536 Query: 605 AAAAAAAKAAAKAAQFGLVGAAGLGGLGV-GGLGVPGVGGLGGIPPAAAAKAAKYGAAGL 663 + G G G G+G+ G +G PG+ G G P Y GL Sbjct: 1537 -----------PKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEP--------GYAKDGL 1577 Query: 664 GGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKAC 700 G+ G G+ G A PG P P G C C Sbjct: 1578 PGIPGPQGE---TGPAGHPGLP-GPPGPPGQCDPSQC 1610 Score = 111 bits (277), Expect = 3e-24 Identities = 192/650 (29%), Positives = 232/650 (35%), Gaps = 114/650 (17%) Query: 18 LSILHPSRPGGVPG--AIPG--GVPG--GVFYPGAGLGALGG-GALGPGGKP-----LKP 65 + + P P G PG PG G+PG G P GA G G GP GKP L P Sbjct: 1044 IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSP 1103 Query: 66 VPGGLAGAGL-------GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVP 116 L + GL P F G VPG K +AG GL G P Sbjct: 1104 GDINLLAKDVCNDCPPGPPGLPGLPG--FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 1161 Query: 117 GVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK 176 G+ G S G + GA + G+ G PGV PG PG P Sbjct: 1162 GIAGPQGSQG----ERGADGEVGQKGDQGHPGV-----------PGFMGPPGNPG----P 1202 Query: 177 PKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 232 P A G+ GA AG PG+ G G P P P G P +PG G GK GP Sbjct: 1203 PGADGIAGA-AGPPGIQGSPGKEGPPGPQGPSGLP----GIPGEEGKEGRDGKP----GP 1253 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G AG+ G P GP+ A +GA G G G+PG G +PG Sbjct: 1254 PGEPGKAGEPGLP-----GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG-LPGK 1307 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----------GVP 342 G G P K G+ PG PG PG G PG G+P Sbjct: 1308 DGDTGPTGPQGPQGPRGPP--GKNGS-----PGSPG-EPGPSGTPGQKGSKGENGSPGLP 1359 Query: 343 GV----GVPGA-GIPVVPGA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 395 G G PG G VPG G+PG PG G + G GIP Sbjct: 1360 GFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIP 1419 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGL 454 G G G +G G+PG G G G PG G PG+ G SP + + G Sbjct: 1420 ----GHKGHTGL-MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474 Query: 455 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAA 513 +A + P + G PG PG PG G G G + Sbjct: 1475 QLETRLAYLLAQMPPAYMKSSQG-RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533 Query: 514 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 573 + K + A GA GL +G PG+ G PG G+PG Sbjct: 1534 PIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-GLPG------------- 1579 Query: 574 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 623 +PG G G G G+PG G + A A+ AA+ G V Sbjct: 1580 ------IPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623 Score = 92.0 bits (227), Expect = 2e-18 Identities = 140/471 (29%), Positives = 168/471 (35%), Gaps = 74/471 (15%) Query: 271 AGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAA----AAAAAAKAAKYGAAAGL-VPG 325 AG +G AG G+PG IG I VG P + G L +PG Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPG 539 Query: 326 GPG--FGPGVVGVPG----AGVPG-VGVPG----AGIPVVPG-AGIPG------------ 361 PG G+ G PG G+PG VG+ G G+P PG G PG Sbjct: 540 PPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRG 599 Query: 362 ----------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 PG + + A G + VG G P G PG V Sbjct: 600 EKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP-------GVPGSVVQQ 652 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGL--------VPGVGVA 461 G+ G G PG G G G PG I PE + G +PG+ Sbjct: 653 EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGL 712 Query: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQ 520 G PGV PG G +PG+ PG PG PG GP G K + Sbjct: 713 QGPPGPPGVPGPPGPGGSPGL---PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769 Query: 521 --LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKY 576 R GL G PGL +G GL AG PG AG+PG PG + K Sbjct: 770 PGERGEDGL-PGKPGLRGEIGEQGL---AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825 Query: 577 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGG 635 +PG+ G G G G P G G P + + G G G GL G G Sbjct: 826 ELGLPGLKGDRGEKGEAG-PAGPPGL-PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883 Query: 636 L-GVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 L G PG G G PP A + +GA G G G G G + PG Sbjct: 884 LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 934 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 145 bits (366), Expect = 1e-34 Identities = 226/727 (31%), Positives = 268/727 (36%), Gaps = 118/727 (16%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPG--GLAGA-GLGAGLGAFP 83 G+PGA PG G + PG G GP G P L+ VPG GL G GL A LG+ P Sbjct: 888 GMPGA-PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLP 946 Query: 84 AVTFPGALVPGGVADAAAA---YKAAKAGAGLGGVPGVGGLGVSAGAVVP--QPGAGVK- 137 + G A Y K G G+PGV GL A + +P A Sbjct: 947 IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEAR 1006 Query: 138 -------PGKVPGVGLPGVYPGGVLPGARF----PGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG V GLPG PG LPG R PG+ PG P G PG GA Sbjct: 1007 GDNSEGDPGCVGSPGLPGP-PG--LPGQRGEEGPPGMRGSPGPPGPIG----PPGFPGA- 1058 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGY 244 G PG+ G + L P PG G P TG LP G G G+AG+ G Sbjct: 1059 VGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE 1118 Query: 245 PTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 P G GP A + + +G G G G PG PG PG G VG+ Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP-PGFPG--KVGS 1175 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----GVPGAGIPVVP 355 P A G + +PG PG PG G+ G AG+ G+ G PG Sbjct: 1176 PGPPGPQAEKGSEGIRGPSG--LPGSPG-PPGPPGIQGPAGLDGLDGKDGKPGL------ 1226 Query: 356 GAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVG 410 G PG A PG++ P G + G G P T GA G PG G Sbjct: 1227 -RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQG 1285 Query: 411 VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 470 G PG G PG G PG G+ VG+ + A G+ PG PG Sbjct: 1286 RPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGER---------GLAGLPGQPGPPGH 1336 Query: 471 GVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 529 PG PG A G PG G GP G AA + K RA G Sbjct: 1337 PGPPG---EPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKG--RAGMPGGP 1391 Query: 530 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-------------------- 569 G G VG PG G PG +G PG VPG++ Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451 Query: 570 AAKAAKYG---------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 620 + A Y AA PG G G G G PG P + + + Q Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-----APGSPGLPGQIGREGRQ- 1505 Query: 621 GLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLG 676 GL G GL G G G+G+ G GL G PP YG G G +G G + Sbjct: 1506 GLPGVRGLPGTKGEKGDIGIGIAGENGLPG-PPGPQGPPG-YGKMGATGPMGQQG---IP 1560 Query: 677 GVAARPG 683 G+ PG Sbjct: 1561 GIPGPPG 1567 Score = 134 bits (336), Expect = 4e-31 Identities = 216/754 (28%), Positives = 258/754 (34%), Gaps = 120/754 (15%) Query: 26 PGGVPG----AIPG--GVPGGVFYPGAGLGALG-GGALGPGGKPLKPVPGGLAG------ 72 P G+PG +PG G PGG P G+ G G GPGGKP KP G G Sbjct: 451 PPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVC 510 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLG-VSAGAVVPQ 131 L G F V PG P G A+ G+ G+ G G +S +VV Sbjct: 511 PTLPEGFQNF--VGLPGKPGPKGEPGDPV---PARGDPGIQGIKGEKGEPCLSCSSVVGA 565 Query: 132 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 191 G VG PG LPG+P AGV PG+ G Sbjct: 566 QHLVSSTGASGDVGSPGF---------------GLPGLPGRAGV----PGLKGEKGNFGE 606 Query: 192 VGPFGGPQPGVPLG-YPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 250 GP G P P P+G IK K P + + G +G+ G P G Sbjct: 607 AGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGF 666 Query: 251 GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA--- 307 G A + K G AG G G PG G PG+ G GV PA Sbjct: 667 GLPGKQGKAGERGLKGQKGDAG---NPGDPGTPGTTGR-PGLSGEPGVQGPAGPKGEKGD 722 Query: 308 AAAAKAAKYGAAAGLV--PGGPG----FGPGVVGVPG----AGVPGV-GVPG----AGIP 352 A + G + PG PG GP VG PG G+PGV G PG G P Sbjct: 723 GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEP 782 Query: 353 VVPGAGI------PGA-AVPGVVSPEAAAKAAAKAAKYGAR--PGV--GVGGIPTYGVGA 401 PG G+ PGA +PG+ + GA+ PGV G + G Sbjct: 783 GPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASV 842 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP-EAQAAAAAKAAKYGLVPGVGV 460 G PG G G G+ G PG G G G PG P + + GL G Sbjct: 843 SGPPGRD-GQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSW 901 Query: 461 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIG------------------ 501 PG PG+ PG PG+ PG PG G+ +G Sbjct: 902 QPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQ 961 Query: 502 -----PG--------------GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPG 542 PG GV A + + RA G G VG PG Sbjct: 962 GQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPG 1021 Query: 543 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV--PGVLGGLGALGGVGIPGGVV 600 L G+PG G PG PG + AV PG+ G G G G+ G Sbjct: 1022 LPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKG 1081 Query: 601 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI--PPAAAAKAAKY 658 GP A G+ G G G G G PG G G+ PP A + Sbjct: 1082 EPGPPGQPGYPGATGPPGLPGIKGERGYTG-SAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140 Query: 659 GAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 G G G G G G PG P FPG Sbjct: 1141 GPQGNSGEKGDQGFQGQPGFPGPPG---PPGFPG 1171 Score = 125 bits (314), Expect = 1e-28 Identities = 219/753 (29%), Positives = 264/753 (35%), Gaps = 126/753 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPG--------GKP-LKPVPGGLAG 72 PS G PG G+PG G GL G A PG G+P L PG Sbjct: 654 PSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGP 713 Query: 73 AG----LGAGLGAFPAVTF--------PGALVPGGVADAAAAYKAAKAGA-GLGGVPGVG 119 AG G G A P++ PG P G + K G GL GV G Sbjct: 714 AGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPP 773 Query: 120 GLGVSAGAVVPQPGAGVK-PGKVPGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 177 GL G P PG GV+ P PG GLPG+ LPG R P PG PTG Sbjct: 774 GLKGVQGEPGP-PGRGVQGPQGEPGAPGLPGIQG---LPGPRGP-----PG-PTGEKGAQ 823 Query: 178 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 237 +PGV GA GP G PG + P G GL T G+ GP G G Sbjct: 824 GSPGVKGA------TGPVG--PPGASVSGPPGRDGQQGQTGLRGTPGEK----GPRGEKG 871 Query: 238 AAGKAGYPT-GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPG--AIPGIG 293 G+ P+ G + A + + G G PG+ G G PGVPG +PG Sbjct: 872 EPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGP-PGIPGPPGPPGVPGLQGVPGNN 930 Query: 294 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGG---PGF--------GPGVVGVPGA--- 339 G+ G A + + V G PG+ G+ GVPG Sbjct: 931 GLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNC 990 Query: 340 ----------------GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 383 G G PG V G+PG PG+ Sbjct: 991 AQCFLSLERPRAEEARGDNSEGDPGC----VGSPGLPGP--PGLPGQRGEEGPPGMRGSP 1044 Query: 384 GARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGGVPGV-GI 437 G +G G P VG+ G PG G+ G G G PG G PG G PG+ GI Sbjct: 1045 GPPGPIGPPGFPG-AVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGI 1103 Query: 438 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVA 497 E +A PG PG G G G G PG Sbjct: 1104 KGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163 Query: 498 PGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGA 556 PG P G S +A+ + G +G+PG G PG+ AG+ GL Sbjct: 1164 PG--PPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKD 1221 Query: 557 GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-----GVVGA-GPAAAAAA 610 G PG PG A PG++G G G G PG G G GP + Sbjct: 1222 GKPGLRGDPGP----------AGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGR 1271 Query: 611 AKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGA 670 A + G G G G VG G PG G GI A GL G G Sbjct: 1272 PGAEGEPGAMGPQGRPGPPG-HVGPPGPPGQPGPAGI-----------SAVGLKGDRGAT 1319 Query: 671 GQFPLGGVAARPGFGLSPIFPGGACLGKACGRK 703 G+ L G+ +PG P PG A G++ Sbjct: 1320 GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKE 1352 Score = 119 bits (298), Expect = 1e-26 Identities = 194/652 (29%), Positives = 224/652 (34%), Gaps = 106/652 (16%) Query: 99 AAAAYKAAKAGAGLGGVPGV----GGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGV 154 A + K K GL G PG G G + P G G G Sbjct: 331 APSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSG 390 Query: 155 LPGARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVP--------L 204 LPG+ G G G+K P PG G I +GP G Q G P Sbjct: 391 LPGST--GEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKG--QKGDPGFVGPEGLA 446 Query: 205 GYPIKAPKLPG--GYGLPYTTGKLPYG-------YGPGGVAGAAGKAGYPTGTGVGPQAA 255 G P P LPG G GLP T G P G G G+ G G G P GV + Sbjct: 447 GEP-GPPGLPGPPGIGLPGTPGD-PGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKG 504 Query: 256 AAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVP---GAIPGIGGIAG-VGTPAAAAAAAAA 310 G LPG G G PG P PGI GI G G P + ++ Sbjct: 505 DPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVG 564 Query: 311 AKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-------------GVPGAGIPVVPG 356 A+ A G PGF G+ G+PG AGVPG+ G PG PV P Sbjct: 565 AQHLVSSTGASGDVGSPGF--GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGP- 621 Query: 357 AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV------- 409 AGI GA A + + A PG P+ G G PGFG+ Sbjct: 622 AGIKGAKGEPCEPCPALSNLQDGDVRVVALPG------PSGEKGEPGPPGFGLPGKQGKA 675 Query: 410 ---GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK----------YGLVP 456 G+ G G AG PG G PG G PG+ P Q A K K G V Sbjct: 676 GERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVT 735 Query: 457 GVGVAPGVGVAPGVGVAPGVGL--APGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAA 513 + PG G GVG PG PGV PG+ GV GP G Sbjct: 736 DMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGE 795 Query: 514 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 573 G PGL G+ GL G PG G G V G A Sbjct: 796 ---------------PGAPGL---PGIQGLPGPRGPPGPTGEKGAQGSPGVKG--ATGPV 835 Query: 574 AKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV--GAAGLGGL 631 GA+V G G G G G+ G GP + +Q L+ G G GL Sbjct: 836 GPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGL 895 Query: 632 GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 +G PG G PP G GL GV G G G+ A G Sbjct: 896 WMGSSWQPGPQG----PPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELG 943 Score = 99.0 bits (245), Expect = 1e-20 Identities = 143/452 (31%), Positives = 174/452 (38%), Gaps = 77/452 (17%) Query: 25 RPG--GVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGL 79 +PG G PG P G PG V PG G A G G GP G P P P G G AGL Sbjct: 1157 QPGFPGPPG--PPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214 Query: 80 GAFPAVTF-------PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQP 132 PG P G+ +K GL G G G G+ +P Sbjct: 1215 DGLDGKDGKPGLRGDPGPAGPPGLM-GPPGFKGKTGHPGLPGPKGDCGKPGPPGST-GRP 1272 Query: 133 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-------- 184 GA +PG + G PG PG V P PG PG P AG+ A G+ G Sbjct: 1273 GAEGEPGAMGPQGRPGP-PGHVGP----PGP---PGQPGPAGIS--AVGLKGDRGATGER 1322 Query: 185 AFAGIPGV-GPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGYGPGGVAGA 238 AG+PG GP G P P G A P G YG P G P G G AG Sbjct: 1323 GLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD-PGAAGQKGQAGE 1381 Query: 239 AGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAG 297 G+AG P G G A + G A PG G+ G+PGVPG++ + Sbjct: 1382 KGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGA---PGPSGSPGLPGVPGSMGDMVNYDE 1438 Query: 298 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIPVVP 355 + + Y + P PG G PG G PG PGA G P +P Sbjct: 1439 IKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR--PGAPGSPGLP 1496 Query: 356 GA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV----GAGG 403 G G+PG +PG G + +G+G G+ G G Sbjct: 1497 GQIGREGRQGLPGVRGLPGTK---------------GEKGDIGIGIAGENGLPGPPGPQG 1541 Query: 404 FPGFG-VGVGGIPGVAGVPGVGGVPGVGGVPG 434 PG+G +G G G G+PG+ G PG G PG Sbjct: 1542 PPGYGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573 Score = 75.5 bits (184), Expect = 2e-13 Identities = 119/410 (29%), Positives = 144/410 (35%), Gaps = 62/410 (15%) Query: 322 LVPGGPGFGPGVVGVPGAGVPG-VGVPGAG----IPVVPGAGIPGAAVP-------GVVS 369 L P GP G G G+PG PG G GA + + P A + A P G + Sbjct: 330 LAPSGPKGGKGERGLPGP--PGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALG 387 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGIP--------------TYGVGAGGFPGFGVGVGGIP 415 P + + + G + G+ G+P G G PGF VG G+ Sbjct: 388 PSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGF-VGPEGLA 446 Query: 416 GVAGVPGVGGVPGVG-----GVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG- 469 G G PG+ G PG+G G PG P+ ++ K G G PGV G Sbjct: 447 GEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEG-PGGKPGKPGVKGEKGD 505 Query: 470 -VGVAPGV--GLAPGVGV--APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 524 V P + G VG+ PG PG V P G G+ + Sbjct: 506 PCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPV-PARGDPGIQGIKGEKGEPCLSCSSVVG 564 Query: 525 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 584 A G VG PG G+PGL AGVPG G +G A P Sbjct: 565 AQHLVSSTGASGDVGSPGF----GLPGLPGRAGVPGLKGEKG--------NFGEAGPA-- 610 Query: 585 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 644 G G G VG P G+ GA A Q G V L G G G PG G Sbjct: 611 GSPGPPGPVG-PAGIKGA--KGEPCEPCPALSNLQDGDVRVVALPGPS-GEKGEPGPPGF 666 Query: 645 GGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 G P KA + G G G G G G RPG P G A Sbjct: 667 G--LPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPA 714 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 144 bits (362), Expect = 4e-34 Identities = 219/697 (31%), Positives = 260/697 (37%), Gaps = 105/697 (15%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 +P PG A P G PG + P G +GG G GP G P P G G +GL Sbjct: 2151 NPGLPGERGMAGPEGKPG-LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP---SGLK 2206 Query: 81 AFPAVTFPGALVPG-GVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 P T P PG G+ A GL G PG GL V PQ G+ PG Sbjct: 2207 GEPGETGP----PGRGLTGPTGA-------VGLPGPPGPSGL------VGPQGSPGL-PG 2248 Query: 140 KVPGVGLPGVYPG-----GVLPGARFPGVGVLPGVPTGAGVK--PKAPGVGG-AFAGIPG 191 +V G PG PG G PGV PG+P G K P G G A G+PG Sbjct: 2249 QVGETGKPGA-PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307 Query: 192 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVG 251 G PG G + P G GLP GP G G AG+AG P G Sbjct: 2308 AKGEKGA-PGGLAGDLVGEPGAKGDRGLP----------GPRGEKGEAGRAGEPGDPGED 2356 Query: 252 PQAAAAAAAKAAAKFGAGAAGVL-----PGV-GGAGVPGVPGAIPGIGGIAG-------V 298 Q A G G G PGV G G+PG+PGA PG+ G G + Sbjct: 2357 GQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA-PGVVGFPGQTGPRGEM 2415 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPGVGVPGA-- 349 G P + A + G L P GP PG VG PGA G PGVG+PG Sbjct: 2416 GQPGPSGERGLAGPPGREGIPGPLGPPGP---PGSVGPPGASGLKGDKGDPGVGLPGPRG 2472 Query: 350 --GIPVVPGA-GIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFP 405 G P + G G PG P G+ P + + G+ G G +G G P Sbjct: 2473 ERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG-P 2531 Query: 406 GFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVG 465 G G G G+ G G G G PG + GL PG+ G Sbjct: 2532 RGAKGDMGERGPRGLDGDKGPRGDNGDPG----DKGSKGEPGDKGSAGL-PGLRGLLGPQ 2586 Query: 466 VAPGVGVAPGVGLAPGVGVAPGV-GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 524 PG PG +PG PG+ G VG +GP G+ + ++ A Sbjct: 2587 GQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLKG----------ERGVKGA 2633 Query: 525 AGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAAV 580 GL G G G PGL AG G GVPG PG L K + Sbjct: 2634 CGLDGEKGDKGEAGPPGRPGL---AGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQ 2690 Query: 581 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG 640 PG G G G G PG GP+ +A G G GL G G G PG Sbjct: 2691 PGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG-QKGERGPPG 2749 Query: 641 --VGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPL 675 V G G+ P A + + G G G G G+ L Sbjct: 2750 ERVVGAPGV-PGAPGERGEQGRPGPAGPRGEKGEAAL 2785 Score = 142 bits (358), Expect = 1e-33 Identities = 233/772 (30%), Positives = 276/772 (35%), Gaps = 163/772 (21%) Query: 26 PGGVPG--AIPG--GVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P G PG + G G PG PG LG G G G G+P KP GL G G G Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 P K + G G PG+ G PG PG Sbjct: 2055 GRPGER------------GERGEKGERGEQGRDGPPGLPGT----------PGPPGPPGP 2092 Query: 141 VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGV-GPFGG 197 V PG PG L G + P PG+ GA +P + G G G+PG+ G G Sbjct: 2093 KVSVDEPG--PG--LSGEQGP-----PGLK-GAKGEPGSNGDQGPKGDRGVPGIKGDRGE 2142 Query: 198 PQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV----G 251 P P G P LPG G+ GK L GP G G G G P G+ G Sbjct: 2143 PGPRGQDGNP----GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG-VGTPA 302 PQ + + + G G+ G G+PG PG PG+ G G G P Sbjct: 2199 PQGPSGLKGEPG-ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPG 2257 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG---VGVPGA-GIPVV 354 A A+ K G+ VPG PG PG VG G G PG VG+PGA G Sbjct: 2258 APGRDGASGKDGDRGSPG--VPGSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA 2314 Query: 355 PG------AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF 407 PG G PGA G+ P A +A + G G G P G GF G Sbjct: 2315 PGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP----GPKGFKGD 2370 Query: 408 -GVGVGGIPGVAGVPGVG---GVPGVGGVPGV-----GISPEAQAAAAAKAAKYGLV--P 456 GVGV G PG G PGV G+PG+ G PGV P + + + GL P Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430 Query: 457 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGV--------APGI-------- 500 G PG PG PG PG G PGVG+ PGI Sbjct: 2431 GREGIPGPLGPPG---PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG 2487 Query: 501 --GPGGVAAAAKSAAKVAAKAQLRAAAGLG------------------------------ 528 GP G+ S + K + +A G Sbjct: 2488 QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD 2547 Query: 529 --------AGIPGLGVGVGVPGLGVGAGVPGL-GV--GAGVPGFGAVPGALAAAKAAKYG 577 G PG G PG AG+PGL G+ G PG +PG K G Sbjct: 2548 GDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPG--DPGSPGKDG 2605 Query: 578 AAVPGVLGGLGALGGVGIPGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 636 VPG+ G G +G +G P G+ G G A + G G GL G G + Sbjct: 2606 --VPGIRGEKGDVGFMG-PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAG-HKGEM 2661 Query: 637 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSP 688 G PGV G G P K G G G G G G PG G P Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPK-GDRGFDGQPGPKGDQGEKGERGTPGIGGFP 2712 Score = 135 bits (340), Expect = 1e-31 Identities = 209/719 (29%), Positives = 243/719 (33%), Gaps = 125/719 (17%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 P G PG +PG G PG PG+ G G G+P P G G GL P Sbjct: 1270 PPGDPG-LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSP 1328 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG--VGGLGVSAGAVVPQPGAGVKPGKV 141 +PG D + + G G PG +GG G PG PG Sbjct: 1329 G-------LPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR 1379 Query: 142 PGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-PKAPGVGGAFAGIPGV-GPFGGPQ 199 +G PG LPG + G G + P PG GG G PG+ G G P Sbjct: 1380 GPLGDPGPRGPPGLPGT------AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 200 PGVPLGYPIK----------APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 249 P P+G P K AP LPG G P G GP G G G G+P G Sbjct: 1434 PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP----RGPPGAIGPKGDRGFPGPLG 1489 Query: 250 -------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG----AIPGI 292 G + A + AK G G G G PG PG P + Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549 Query: 293 GGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-------FGP----GVVGVPG-A 339 G G G A A + G ++PG PG GP G G PG + Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDS 1609 Query: 340 GVPG----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 395 G PG G PG PV P G P KA + G R GV G P Sbjct: 1610 GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG-P 1668 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 455 G G PG G G PG +G G G PG G PG + A + G Sbjct: 1669 VGEKGDQGDPGED-GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727 Query: 456 --------PGVGVAPGVGVAPGVGVAPGVGLAPGV-GVA--------PGVGVAPGVGVAP 498 PG+ APG G PG PGV G A PG+ G+ P Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787 Query: 499 G-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 557 G GP G AA A G+PGL G+PG G+PG G Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRD-----------GLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836 Query: 558 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 617 PG G PG G G G G G GP A Sbjct: 1837 KPGLNGKNGE----------PGDPGEDGRKGEKGDSGASGREGRDGPKGERGAP------ 1880 Query: 618 AQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQ 672 G++G G GL G G G PGV G G P + G GL G G G+ Sbjct: 1881 ---GILGPQGPPGLPGPVGPPGQGFPGVPG-GTGPKGDRGETGSKGEQGLPGERGLRGE 1935 Score = 125 bits (314), Expect = 1e-28 Identities = 207/727 (28%), Positives = 251/727 (34%), Gaps = 110/727 (15%) Query: 25 RPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKP-VPGGLAGAGLGAGLG 80 +PG + P G G PG GL L G G GP G P P PG GL G Sbjct: 1786 KPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPGK 140 PG PG D K +G G G G + G + PQ G+ PG Sbjct: 1846 E------PGD--PG--EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL-PGP 1894 Query: 141 V--PGVGLPGVYPGGVLP-------GAR----FPGVGVLPGVPTG----------AGVKP 177 V PG G PGV PGG P G++ PG L G P AG+K Sbjct: 1895 VGPPGQGFPGV-PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKA 1953 Query: 178 KA--------PGVGGAFAGIP--------GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPY 221 A G+F +P G G P P+G+P + L G G P Sbjct: 1954 SALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG-LKGDRGDPG 2012 Query: 222 TTGKLPYGYGPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGV 277 G G G G +G AG P G+ G A + + G G Sbjct: 2013 PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQ 2072 Query: 278 GGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 G G PG+PG TP + G G PG G G P Sbjct: 2073 GRDGPPGLPG------------TPGPPGPPGPKVSVDEPGPGLSGEQGPPGL-KGAKGEP 2119 Query: 338 GAGVPGVGVPGAGIPVVPG-AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVG 392 G+ G+P + G G PG PG+ A K G R G Sbjct: 2120 GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPG-- 2177 Query: 393 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQAAAAAKAAK 451 P G G G PG G+ G G G G+ G PG G PG G++ P Sbjct: 2178 --PVGGHGDPGPPG-APGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGP 2234 Query: 452 YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 511 GLV G +PG+ G PG G G +PGV +PG+ PG V + Sbjct: 2235 SGLVGPQG-SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGL-PGPVGPKGEP 2292 Query: 512 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG--AGVPGLGVGAGVPGFGAVPGALA 569 A + G+PG G PG G G PG G+PG G Sbjct: 2293 GPTGAPGQAV-------VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGE-- 2343 Query: 570 AAKAAKYGAAVPGVLGGLGALG--------GVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 621 A +A + G PG G GA G GVG+PG GP G Sbjct: 2344 AGRAGEPGD--PGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPG 2401 Query: 622 LVGAAGLGGLGVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 679 +VG G G G +G PG G G+ PP G G G +G G L G Sbjct: 2402 VVGFPGQTGPR-GEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460 Query: 680 ARPGFGL 686 PG GL Sbjct: 2461 GDPGVGL 2467 Score = 124 bits (312), Expect = 2e-28 Identities = 203/673 (30%), Positives = 237/673 (35%), Gaps = 120/673 (17%) Query: 111 GLGGVPGVGGLGVSAGAVVPQ--------------PGAGVKPGKVPGVGLPGVYPG--GV 154 G G PG GL GA PQ PGA +PG G PG PG G+ Sbjct: 1266 GQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT-PGAPGL 1324 Query: 155 LPGARFPGVGVLPGV--PTGAGVKPKAPG--VGGAFAGIPG----VGPFGGPQPGVPLGY 206 PG PG P G +P APG +GG G+PG GP G P P PLG Sbjct: 1325 KGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGD 1384 Query: 207 PIKAPKLPGGYGLPYTTGKL---------PYGYGPGGVA-GAAGKAGYPTGTGVGPQAAA 256 P P+ P G LP T K P G G GG+A G G G P G PQ Sbjct: 1385 P--GPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG--PQGPV 1438 Query: 257 AAAAKAAAKFGA--GAAGVLPG----------------VGGAGVPGVPGAIPGIGGIAGV 298 K K + GA G LPG +G G G PG + G Sbjct: 1439 GPPGKKGEKGDSEDGAPG-LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497 Query: 299 GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAG 358 G P A + A + GA P GP G G PG G P V G Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR---------PGDPAVVGPA 1548 Query: 359 IPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG----FGV-GVG 412 + G G V P A + G PG+ + G P G G PG G+ G Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDP----GPKGDPGDRGPIGLTGRA 1603 Query: 413 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 472 G PG +G PG G PG G PG + P + + G PG PG G+ Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPG-PVGPRGRDGEVGEKGDEG-PPGDPGLPGKAGERGLRG 1661 Query: 473 APGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-- 529 APGV G G G +PG GP G G GA Sbjct: 1662 APGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD----TGPGARE 1717 Query: 530 -GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLG 588 G PG G G G+PG G+ GF PG + A G G G Sbjct: 1718 KGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP-QGDPGVRGPAGEKGDRGPPG 1776 Query: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL----GVGGL-------G 637 G G+ G AGP+ AA A + GL G G GL G GL G Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836 Query: 638 VPGVGGLGGIP--PAAAAKAAKYGAAGLG---------------GVLGGAGQFPLGGVAA 680 PG+ G G P P + + G +G G+LG G L G Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896 Query: 681 RPGFGLSPIFPGG 693 PG G P PGG Sbjct: 1897 PPGQGF-PGVPGG 1908 Score = 124 bits (310), Expect = 4e-28 Identities = 199/707 (28%), Positives = 248/707 (35%), Gaps = 118/707 (16%) Query: 28 GVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G G PG G+ GP G +P P G G + G Sbjct: 1661 GAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG-------- 1712 Query: 87 FPGALVPGGVADAAA-AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK--PGKVPG 143 PGA G D + K GL G PG G+ G PQ GV+ G+ Sbjct: 1713 -PGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGD 1771 Query: 144 VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGV 202 G PG+ L G PG P P GA K PG G +PG+ G G P P Sbjct: 1772 RGPPGLDGRSGLDGK--PGAAG-PSGPNGAAGKAGDPGRDG----LPGLRGEQGLPGPSG 1824 Query: 203 PLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-------VGPQAA 255 P G P K PG G P G GK G P G G A Sbjct: 1825 PPGLPGK----PGEDGKP----------------GLNGKNGEPGDPGEDGRKGEKGDSGA 1864 Query: 256 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 315 + + K GA G+L G G PG+PG + G G G P + Sbjct: 1865 SGREGRDGPKGERGAPGIL---GPQGPPGLPGPV----GPPGQGFPGVPGGTGPKGDRGE 1917 Query: 316 YGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVS------ 369 G+ G PG G+ G PG+ VP V ++ AGI +A+ +V Sbjct: 1918 TGSKG--EQGLPG-ERGLRGEPGS-VPNVD------RLLETAGIKASALREIVETWDESS 1967 Query: 370 ------PEAAAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGFGVGVGGIP 415 PE + + G G G P G G PG +G G P Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027 Query: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 475 G +G+ G G PG+ G+PG +A +A + G G G G PG Sbjct: 2028 GPSGLAGEPGKPGIPGLPG-------RAGGVGEAGRPG-ERGERGEKGERGEQGRDGPPG 2079 Query: 476 VGLAPGVGVAPGVGVA---PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 532 + PG PG V+ PG G++ GP G+ A + G+P Sbjct: 2080 LPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG-----DRGVP 2134 Query: 533 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 592 G+ G PG G PGL G+ G PG PG +GG G G Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP-------RGPPGPVGGHGDPGP 2187 Query: 593 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-GVPGVGGLGGIP--- 648 G PG AGPA + + + G G G G GL G PG GL G Sbjct: 2188 PGAPG---LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSP 2244 Query: 649 --PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGG 693 P + K GA G G G G GV PG P+ P G Sbjct: 2245 GLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLP-GPVGPKG 2290 Score = 98.6 bits (244), Expect = 2e-20 Identities = 148/495 (29%), Positives = 169/495 (34%), Gaps = 77/495 (15%) Query: 227 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 285 P G G G G G P TG GPQ +A + GA G G AG PG Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT 1318 Query: 286 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG-AGVPG 343 PGA PG+ G G+ P A G V GG G G PG G PG +G PG Sbjct: 1319 PGA-PGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPG 1377 Query: 344 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 399 +G PG P G+PG A+ G PG G GGI Sbjct: 1378 PRGPLGDPGPRGP----PGLPGTAMKGDKGDRGER----------GPPGPGEGGIAPGEP 1423 Query: 400 GAGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 443 G G PG G G PG+ G PG G G G PG I P+ Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG-AIGPKGDR 1482 Query: 444 AAAAKAAKYGL--------------VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVG 489 + G +PGV PG A G PG G PG Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG---AKGPEGPPGPTGRQGEKGEPGRP 1539 Query: 490 VAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAG 548 P V V P + GP G A A G +PG G PG G Sbjct: 1540 GDPAV-VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPG---DRG 1595 Query: 549 VPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 608 GL AG PG PG PG G G +G G G V G Sbjct: 1596 PIGLTGRAGPPGDSGPPGE----------KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645 Query: 609 AAAKAAAKAAQFGLVGAAGL-GGLG-VGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGV 666 KA + GL GA G+ G +G G G PG G G P ++ K G G G Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK----GDRGEPGP 1701 Query: 667 LGGAGQFPLGGVAAR 681 G G+ G AR Sbjct: 1702 PGPPGRLVDTGPGAR 1716 Score = 81.6 bits (200), Expect = 2e-15 Identities = 130/432 (30%), Positives = 157/432 (36%), Gaps = 64/432 (14%) Query: 269 GAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG 328 G G + G G PG PG +PG G G P +A A G G Sbjct: 1257 GEPGEMGLRGQVGPPGDPG-LPGRTGAPGPQGPPGSATA----------------KGERG 1299 Query: 329 FGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARP 387 F PG G PG+ PG AG P PGA G+ G+ PG+ P + G R Sbjct: 1300 F-PGADGRPGS--PG----RAGNPGTPGAPGLKGS--PGLPGPR------GDPGERGPRG 1344 Query: 388 GVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV---PGVGGVPGV-GISPEAQA 443 G G P +G G PG G G PG +G PG G PG G PG+ G + + Sbjct: 1345 PKGEPGAPGQVIGGEG-PGL-PGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDK 1402 Query: 444 AAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPG 503 + G PG G G+APG PG+ +PG G G G Sbjct: 1403 GDRGERGPPG--PGEG-----GIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAP 1455 Query: 504 GVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 562 G+ S + + A G G PG +G G G PG G+PG Sbjct: 1456 GLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG---PLGEAGEKGERGPPGPAGSRGLPGVA 1512 Query: 563 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 622 PG AK PG G G G G PG GPA A + G Sbjct: 1513 GRPG-------AKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGE-KGDVGPAGP 1564 Query: 623 VGAAGL-GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAAR 681 GA G+ G G GL +PG G G P G G G G +G G R Sbjct: 1565 RGATGVQGERGPPGLVLPGDPGPKGDP----GDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620 Query: 682 PGFGLSPIFPGG 693 PG P+ P G Sbjct: 1621 PG-PPGPVGPRG 1631 Score = 68.6 bits (166), Expect = 2e-11 Identities = 90/288 (31%), Positives = 105/288 (36%), Gaps = 39/288 (13%) Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G PG G+ G G PG G+PG +P Q PG A G PG Sbjct: 1254 GQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGP-----------PGSATAKGERGFPG 1302 Query: 470 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GP-GGVAAAAKSAAKVAAKAQLRAAAGL 527 PG +PG PG APG+ +PG+ GP G K A + G Sbjct: 1303 ADGRPG---SPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGE 1359 Query: 528 GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG----ALAAAKAAKYGAAVPGV 583 G G+PG G PG +G PG G PG PG A+ K + PG Sbjct: 1360 GPGLPG---RKGDPG---PSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGP 1413 Query: 584 LGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 643 G A G G+PG GP + GA GL G G PG G Sbjct: 1414 GEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGD-SEDGAPGLPGQP----GSPGEQG 1468 Query: 644 LGGIPPAAAAKA--------AKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G P A K + G G G G AG L GVA RPG Sbjct: 1469 PRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG 1516 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 144 bits (362), Expect = 4e-34 Identities = 212/744 (28%), Positives = 268/744 (36%), Gaps = 115/744 (15%) Query: 23 PSRPGGVPGAI----PGGVPGGVFYPGA-GLGALGGGALGPGGKPLKPVPGGLAGAGLGA 77 P P G+PG P G+PG PG GL G PG P +PVPG GL Sbjct: 499 PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558 Query: 78 -----------GLGAFPAVT-FPGAL-VPGGVADAAA-AYKAAKAGAGLGGVPGVGGLGV 123 GL P + PG +PG + + Y + AG G PG G Sbjct: 559 LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKG--- 615 Query: 124 SAGAVVPQPGAGVKPGKVPGVGLPGV-----------YPGGVLPGARFP-GVGVLPGVPT 171 A + PG + G G+PG+ +PG G R P G+ PG+ Sbjct: 616 -AQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF--GDRGPAGLDGSPGLVG 672 Query: 172 GAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 231 G G P PG+ G+ + +GP G P P +G L G GLP G G Sbjct: 673 GTG-PPGFPGLRGSVGPVGPIGPAGIPGP---MG-------LSGNKGLPGIKGDK----G 717 Query: 232 PGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--A 288 G AG G+ GYP G VG K+ G G+ G G G PG Sbjct: 718 EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777 Query: 289 IPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-G 340 IPG G G G P + GA L P G G G PG G Sbjct: 778 IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837 Query: 341 VPG-------VGVPGAGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVG 392 + G +G G PV G+PG + G + + + G + +G Sbjct: 838 LKGEVGDQGNIGKIGETGPV----GLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYP 893 Query: 393 GIPTYG--VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GIS-PEAQAAAAAK 448 G P +G G PG VG G PG G G G G G+ G GI + + K Sbjct: 894 GPPGVPGPIGPLGLPGH-VGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGK 952 Query: 449 AAKYGLVPGVGVAPGVGVA--PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GP 502 +GL+ G G PG+ PG G+ PG+ G PG GP Sbjct: 953 RGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGP 1012 Query: 503 GGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 561 G + + AK + A +G G PGL G PG G GL GVPG Sbjct: 1013 PGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGL---KGVPGG 1069 Query: 562 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKAAAKAAQ 619 +PG K +PG++G LG G G+PG G+VG P K K Q Sbjct: 1070 RGLPGE----DGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGI-PGQRGRPGKKGDKG-Q 1123 Query: 620 FGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVA 679 G G G G PP K+ GA G G +G G G Sbjct: 1124 IGPTGEVGSRG-----------------PPGKIGKSGPKGARGTRGAVGHLGLMGPDGEP 1166 Query: 680 ARPGFGLSPIFPGGACLGKACGRK 703 PG+ PG + L G K Sbjct: 1167 GIPGYRGHQGQPGPSGLPGPKGEK 1190 Score = 127 bits (319), Expect = 4e-29 Identities = 221/800 (27%), Positives = 276/800 (34%), Gaps = 157/800 (19%) Query: 22 HPSRPGGVPG--AIPG--GVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPGGLAGAGLG 76 HP PG +PG IPG G G YPG G GP G P K G + G Sbjct: 574 HPGLPG-LPGEQGIPGFAGNIGSPGYPGRQ------GLAGPEGNPGPKGAQGFIGSPGEA 626 Query: 77 AGLGAFPAVTFPGAL----------VPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSA 125 LG PG PG D A G G G PG GL S Sbjct: 627 GQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSV 686 Query: 126 GAVVPQPGAGVKPGKVP---GVGLPGVY-------PGGVLPGARFPGVGVLPGVPTGAGV 175 G V P AG+ PG + GLPG+ G L +PG G+P G+ Sbjct: 687 GPVGPIGPAGI-PGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGM 745 Query: 176 KPKAPGVGGAFAGIPGV-GPFGGPQP-------GVPLGYPIKAPK-------LPGGYGLP 220 + K+ G G PG+ GP G P P G+P + PK PG GL Sbjct: 746 RGKSGPSGQT--GDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLK 803 Query: 221 YTTGKL-PYG----YGPGGVAGAAGKAGYPTGTG-------------------VGPQAAA 256 T G+ P G GP G G G AG P G VG Sbjct: 804 GTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEV 863 Query: 257 AAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAK 315 K G+ G L G GV G PG PG+ G G +G P A Sbjct: 864 GMTGSIGEKGERGSPGPLGPQGEKGVMGYPGP-PGVPGPIGPLGLPGHVGARGPPGSQGP 922 Query: 316 YGAAAGLVPGGPGFGPGVVGVPGA-------------------------GVPGV-GVPGA 349 G P G G+ G G G PG+ G+PG+ Sbjct: 923 KGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGS 982 Query: 350 ----GIPVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 400 G+P PG G+ G P G+ P + + GA+ VG G VG Sbjct: 983 TGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAG----SVG 1038 Query: 401 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 460 G PG + G PG G G+ G G+ GVPG G + + G++ +G Sbjct: 1039 GTGEPG----LRGEPGAPGEEGLQGKDGLKGVPG-GRGLPGEDGEKGEMGLPGIIGPLGR 1093 Query: 461 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKA 519 + G+ G+ VG+ PG PG G +G +G G + A+ Sbjct: 1094 SGQTGLPGPEGI---VGI-PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARG 1149 Query: 520 QLRAAAGLGA-------GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAV-------- 564 A LG GIPG G PG +G+PG G PG + Sbjct: 1150 TRGAVGHLGLMGPDGEPGIPGYRGHQGQPG---PSGLPGPKGEKGYPGEDSTVLGPPGPR 1206 Query: 565 --PGALA--------AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA 614 PG + A+ K VPG+ G G G G PG G + Sbjct: 1207 GEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNK 1266 Query: 615 AKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQ 672 K G G G+ GL +G G+ G G GI K G GL G+ GG G+ Sbjct: 1267 GKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGIS-GNPGKIGPPGKQGLPGIRGGPGR 1325 Query: 673 FPLGGVAARPGFGLSPIFPG 692 L G PG S PG Sbjct: 1326 TGLAGAPGPPGVKGSSGLPG 1345 Score = 100 bits (248), Expect = 6e-21 Identities = 192/668 (28%), Positives = 231/668 (34%), Gaps = 131/668 (19%) Query: 26 PGGVPGAI-PGGVPG-----------------GVFYPGAGLGALG-GGALGPGGKPLKPV 66 P GVPG I P G+PG G P LG G GA G G K Sbjct: 895 PPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG 954 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGA----------GLGGV 115 P GL G G F PG +PG D + G G+ G Sbjct: 955 PHGLIGKTGNPGERGFQGK--PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGP 1012 Query: 116 PGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAG 174 PG G G + G G V G G PG+ PG G L GVP G G Sbjct: 1013 PGTEGESGLQGEPGAKGDVGTA-GSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071 Query: 175 VKPKAPGVGGAFAGIPGV-GPFG-GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 232 + P G G G+PG+ GP G Q G+P P +PG G P Sbjct: 1072 L-PGEDGEKGEM-GLPGIIGPLGRSGQTGLP--GPEGIVGIPGQRGRP------------ 1115 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G G+ G PTG VG + K+ K G G + +G G G PG IPG Sbjct: 1116 -GKKGDKGQIG-PTGE-VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPG-IPGY 1171 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GVPG-A 349 G G P+ K + L P GP PG VG G G PG G G Sbjct: 1172 RGHQGQPGPSGLPGPKGE-KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230 Query: 350 GIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAG 402 G+P + GA G PG G + + K GA G GIP +G Sbjct: 1231 GVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK 1290 Query: 403 GFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 460 G G+ G+ G PG G PG G+PG+ G PG Sbjct: 1291 GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPG-------------------------- 1324 Query: 461 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 520 G+ APG PGV + G+ +PG+ G PG PG + K Sbjct: 1325 RTGLAGAPG---PPGVKGSSGLPGSPGIQGPKGEQGLPG-QPG-----------IQGKRG 1369 Query: 521 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 580 R A G G PGL G PG G+ GF PG K + A + Sbjct: 1370 HRGAQGDQG-------PCGDPGL---KGQPGEYGVQGLTGFQGFPG----PKGPEGDAGI 1415 Query: 581 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG 640 G+ G G +G G GP + G G G G G G PG Sbjct: 1416 VGISGPKGPIGHRG------NTGPLGREGIIGPTGRTGPRGEKGFRGETG-PQGPRGQPG 1468 Query: 641 VGGLGGIP 648 G G P Sbjct: 1469 PPGPPGAP 1476 Score = 84.3 bits (207), Expect = 3e-16 Identities = 129/491 (26%), Positives = 178/491 (36%), Gaps = 78/491 (15%) Query: 225 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 284 ++ Y GP G G G G P G GP G G+ G G+PG Sbjct: 483 EMEYLRGPKGDTGPPGPPG-PAGIP-GPSGKR------------GPRGIPGPHGNPGLPG 528 Query: 285 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG 343 +PG G P + + G + + P G G+ G PG G+PG Sbjct: 529 LPGP------KGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPG 582 Query: 344 -VGVPG----AGIPVVPG-------------------AGIPGAA----------VPGVVS 369 G+PG G P PG G PG A +PG+ Sbjct: 583 EQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRG 642 Query: 370 PEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIPGVAGVPGVGG 425 + +G R G+ G P G G GFPG VG G G AG+PG G Sbjct: 643 KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 485 + G G+PG+ + + A + + G PG A G+ PG+ G G Sbjct: 703 LSGNKGLPGIK-GDKGEQGTAGELGEPG-YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGL 760 Query: 486 PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGV 545 G PG P PG + ++ + K L G PGL G G Sbjct: 761 QGPSGPPG----PEGFPGDIGIPGQNGPE-GPKGLLGNRG--PPGPPGLKGTQGEEGPIG 813 Query: 546 GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA- 602 G G G G+ PG + K G +G +G G VG+PG G+ G+ Sbjct: 814 AFGELGPRGKPGQKGYAGEPG----PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869 Query: 603 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGA 660 G + + G++G G G+ +G LG+PG G G PP + + G+ Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARG-PPGSQGPKGQRGS 928 Query: 661 AGLGGVLGGAG 671 G G+LG G Sbjct: 929 RGPDGLLGEQG 939 Score = 75.9 bits (185), Expect = 1e-13 Identities = 130/445 (29%), Positives = 163/445 (36%), Gaps = 62/445 (13%) Query: 28 GVPGAI-PGGVPGGVFYPGA-GLGALGG-----------GALGPGGKP-LKPVPGGLAGA 73 G+PG I P G G PG G+ + G G +GP G+ + PG + + Sbjct: 1083 GLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS 1142 Query: 74 GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAG---AVVP 130 G G AV G + P G Y+ + G G+PG G G V+ Sbjct: 1143 GPKGARGTRGAVGHLGLMGPDG-EPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLG 1201 Query: 131 QPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGV--PTGAGVKPKAPGVGGAFA 187 PG +PG V G G PGA + G +PG+ TG P PG G Sbjct: 1202 PPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE-Q 1254 Query: 188 GIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTG 247 G+ G G + P P +PG GL G Y +G G++G GK G P Sbjct: 1255 GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGY-HGADGISGNPGKIGPP-- 1311 Query: 248 TGVGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAA 305 G Q AGA G PGV G +G+PG PG I G G G+ G P Sbjct: 1312 ---GKQGLPGIRGGPGRTGLAGAPGP-PGVKGSSGLPGSPG-IQGPKGEQGLPGQPGIQG 1366 Query: 306 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGAGIP--GA 362 K G GP PG+ G PG GV G+ G PG P A Sbjct: 1367 ---------KRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL----TGFQGFPGPKGPEGDA 1413 Query: 363 AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG 422 + G+ P+ G +G PT G G GF G G G G Sbjct: 1414 GIVGISGPKGPIGHRGNTGPLGREGIIG----PTGRTGPRGEKGFR----GETGPQGPRG 1465 Query: 423 VGGVPGVGGVPGVGISPEAQAAAAA 447 G PG G PG + AA A Sbjct: 1466 QPGPPGPPGAPGPRKQMDINAAIQA 1490 Score = 65.9 bits (159), Expect = 1e-10 Identities = 84/294 (28%), Positives = 105/294 (35%), Gaps = 71/294 (24%) Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 469 G G G G PG G+PG G G P +PG PG+ PG Sbjct: 489 GPKGDTGPPGPPGPAGIPGPSGKRG----PRG-------------IPGPHGNPGLPGLPG 531 Query: 470 -VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG 528 G G +PG P G G++ +GP G ++ GL Sbjct: 532 PKGPKGDPGFSPG---QPVPGEKGDQGLSGLMGPPG----------------MQGDKGLK 572 Query: 529 A--GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA-------AKAAKYG-- 577 G+PGL G+PG G PG G+ G PG A +A + G Sbjct: 573 GHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPE 632 Query: 578 --AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 635 +PG+ G G G G PG GPA GL G+ GL G G G Sbjct: 633 GERGIPGIRGKKGFKGRQGFPGDFGDRGPA---------------GLDGSPGLVG-GTGP 676 Query: 636 LGVPG----VGGLGGIPPAA-AAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGF 684 G PG VG +G I PA G GL G+ G G+ G PG+ Sbjct: 677 PGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGY 730 Score = 59.3 bits (142), Expect = 1e-08 Identities = 93/340 (27%), Positives = 117/340 (34%), Gaps = 75/340 (22%) Query: 19 SILHPSRPGGVPGAIPG----GVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLA 71 ++L P P G PG + G PG Y G G+ L G G GP G+P G Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP-----GDQG 1252 Query: 72 GAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ 131 GL G+ + K A +G G+PG+ GL G Sbjct: 1253 EQGLKGERGS----------------EGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYH 1296 Query: 132 PGAGVK--PGKV--PGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAF 186 G+ PGK+ PG GLPG+ G PG TG P PGV G+ Sbjct: 1297 GADGISGNPGKIGPPGKQGLPGIRGG---PGR------------TGLAGAPGPPGVKGS- 1340 Query: 187 AGIPGVGPFGGP--QPGVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPGGVAGAAGKA 242 +G+PG GP + G+P G P GK + G G G G Sbjct: 1341 SGLPGSPGIQGPKGEQGLP--------------GQPGIQGKRGHRGAQGDQGPCGDPGLK 1386 Query: 243 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 302 G P GV Q K G AG++ G+ G G I G +G Sbjct: 1387 GQPGEYGV--QGLTGFQGFPGPKGPEGDAGIV------GISGPKGPIGHRGNTGPLGREG 1438 Query: 303 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVP 342 + G P GP PG G PGA P Sbjct: 1439 IIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 143 bits (361), Expect = 5e-34 Identities = 167/524 (31%), Positives = 200/524 (38%), Gaps = 38/524 (7%) Query: 127 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAF 186 AV + G PG G PG PG PG+ PG+P G P A G G Sbjct: 54 AVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG--PSAVGKPGV- 110 Query: 187 AGIPGV----GPFGGPQPGVPLGYPIKAPK-LPGGYGLPYTTG-KLPYGYGPGGVAGAAG 240 G+PG GP+G P G P P+ PG G+P G +P G G GA G Sbjct: 111 PGLPGKPGERGPYGPKGDVGPAGLP--GPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168 Query: 241 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 300 G+P G P K +GA G+ G P P PG+G G Sbjct: 169 PRGFPGEKG-APGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGV 227 Query: 301 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG-VGVPGAGIPVVPGA-G 358 P + G + P GP PG G G G PG G PG P +PG G Sbjct: 228 PGQPGIKGDRGFPGEMGP---IGPPGPQGPPGERGPEGIGKPGAAGAPGQ--PGIPGTKG 282 Query: 359 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVA 418 +PGA PG+ P K G + G G+P G GA G G G+ G PG+ Sbjct: 283 LPGA--PGIAGP-PGPPGFGKPGLPGLKGERGPAGLPG-GPGAKGEQG-PAGLPGKPGLT 337 Query: 419 GVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G PG G G G+PG G+ A A Y G +PG PG PG+ Sbjct: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397 Query: 478 LAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 536 G PG PGVG PG+ GP G A AK +A R A GIPG Sbjct: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVG-PAGAKGMPGHNGEAGPRGA----PGIPGTRG 452 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 +G P G+PG G PG PG A A K PG G G G G+ Sbjct: 453 PIGPP------GIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGL 506 Query: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 639 PG GP A + KA Q + L G G+P Sbjct: 507 PGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550 Score = 127 bits (318), Expect = 5e-29 Identities = 184/579 (31%), Positives = 217/579 (37%), Gaps = 108/579 (18%) Query: 28 GVPG-AIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG A P G PG P G G G+ G G+P P P G + G G+ P Sbjct: 63 GPPGPAGPRGHPG----PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVG-KPGVPGLPGK- 116 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPG----VGGLGVSAGAVVPQPGAGVKPGKVP 142 PG P G K G G+PG G G+ A + PG KPG+ Sbjct: 117 -PGERGPYG----------PKGDVGPAGLPGPRGPPGPPGIPGPAGISVPG---KPGQQG 162 Query: 143 GVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPK----APGVGGAFAGIPGVGPFGGP 198 G PG P G FPG PGVP G K + APG G G+P GP G Sbjct: 163 PTGAPG--PRG------FPGEKGAPGVPGMNGQKGEMGYGAPGRPGE-RGLP--GPQGPT 211 Query: 199 QPGVPLGYPIKAPK-LPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAA 257 P P G + +PG G+ G P GP G G G G G+G AA Sbjct: 212 GPSGPPGVGKRGENGVPGQPGIKGDRG-FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270 Query: 258 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-AIPGIGGIAGVGTPAAAAAAAAAAKAAKY 316 A + G G PG+ AG PG PG PG+ G+ G PA Sbjct: 271 APGQPGIPGTKGLPGA-PGI--AGPPGPPGFGKPGLPGLKGERGPAG------------- 314 Query: 317 GAAAGLVPGGPGF--GPGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGA-AVPGVVSPEA 372 +PGGPG G G+PG PG+ G PG P P GIPG+ +PG Sbjct: 315 ------LPGGPGAKGEQGPAGLPGK--PGLTGPPGNMGPQGP-KGIPGSHGLPGPKGETG 365 Query: 373 AAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGV 432 A A G R G G P G+PG G+ G G G+PG G PGVGG Sbjct: 366 PAGPAGYPGAKGERGSPGSDGKP-------GYPG-KPGLDGPKGNPGLPGPKGDPGVGGP 417 Query: 433 PGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAP 492 PG+ P A AK +PG G APG+ G PG+ PG P Sbjct: 418 PGL---PGPVGPAGAKG-----MPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDP 469 Query: 493 GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL 552 G P GP G+A L G G PG G PGL G P Sbjct: 470 GSPGPP--GPAGIATKG-----------LNGPTG-PPGPPGPRGHSGEPGLPGPPGPP-- 513 Query: 553 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 591 G PG +P A + P V G G Sbjct: 514 ----GPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548 Score = 118 bits (295), Expect = 2e-26 Identities = 163/530 (30%), Positives = 194/530 (36%), Gaps = 97/530 (18%) Query: 193 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY----GPGGVAGAAGKAGYPTGT 248 G F + +P G P + +PYT G G G AG G+P Sbjct: 18 GVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP--- 74 Query: 249 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 308 GP +G G PG G G+ G PG +PG G + VG P Sbjct: 75 --GP---------------SGPPGK-PGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPG 115 Query: 309 AAAKAAKYGAAAGLVPGG---PGFGPGVVGVPG-AGVPGVGVPGAGIPV-VPGA-GIPGA 362 + YG + P G P PG G+PG AG+ G PG P PG G PG Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175 Query: 363 -AVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPGFGV-GVGGIPGV 417 PGV YGA RPG G+ G P G G PG G G G+PG Sbjct: 176 KGAPGVPGMNGQKGEMG----YGAPGRPGERGLPG-PQGPTGPSGPPGVGKRGENGVPGQ 230 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G+ G G PG G G P Q + + G+G PG APG PG Sbjct: 231 PGIKGDRGFPGEMGPIG---PPGPQGPPGERGPE-----GIG-KPGAAGAPGQPGIPGTK 281 Query: 478 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG 537 PG APG+ PG PG G G+ L+ G AG+PG G Sbjct: 282 GLPG---APGIAGPPG---PPGFGKPGLPG-------------LKGERG-PAGLPG---G 318 Query: 538 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGI 595 G G AG+PG PG PG + K +PG G G G G Sbjct: 319 PGAKGEQGPAGLPGK------PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372 Query: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP----PAA 651 PG G + K GL G G GL G G PGVGG G+P PA Sbjct: 373 PGAKGERGSPGSDGKPGYPGKP---GLDGPKGNPGLP-GPKGDPGVGGPPGLPGPVGPAG 428 Query: 652 A-------AKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGA 694 A +A GA G+ G G G + G G SP PG A Sbjct: 429 AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPA 478 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 142 bits (358), Expect = 1e-33 Identities = 234/749 (31%), Positives = 274/749 (36%), Gaps = 107/749 (14%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGP---GGKPLKPVPGGLAGAGLGAGLG 80 P G PG IPG G G + +PG GA GP G P P P G+ G GL Sbjct: 666 PPGNPG-IPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAGAVVPQPGAGV 136 PG D K GA G G G G AG P PG+ Sbjct: 725 GEKGEKGEDGF-PGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGP-PGSAG 782 Query: 137 KPGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 192 + GK+ GLPG YPG PG + FPG + P G K PG+ G G PG Sbjct: 783 EKGKLGVPGLPG-YPGR--PGPKGSIGFPGP-LGPIGEKGKSGKTGQPGLEGE-RGPPGS 837 Query: 193 -------GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAG 243 G G P P +G AP +PG GLP G P GP G G G+ G Sbjct: 838 RGERGQPGATGQPGPKGDVGQD-GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPG 896 Query: 244 YPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-GTP 301 +P G +G Q A G G + +G G PG PG PG G+ G+ G Sbjct: 897 HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGP-PGEQGLPGLEGRE 955 Query: 302 AAAAAAAAAAKAAKYGAAAGL-----VPGGPGFGPGVVGVPG-AGVPGV----GVPGAGI 351 A K G A GL GGPG PG G+ G G PG G PG Sbjct: 956 GAKGELGPPGPLGKEGPA-GLRGFPGPKGGPG-DPGPTGLKGDKGPPGPVGANGSPGERG 1013 Query: 352 PVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 P+ P GI +PG E A K G R G PT G G PG +G Sbjct: 1014 PLGPAGGI---GLPGQSGSEGPVGPAGKKGSRGERGPPG----PT---GKDGIPG-PLGP 1062 Query: 412 GGIPGVAGVPGVGGVPGVGGVPGVGIS--------PEAQAAAAAKAAKYGLVPGVGVAPG 463 G PG AG G G G G PG S P Q A G PG A G Sbjct: 1063 LGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPG-PPGADGAQG 1121 Query: 464 VGVAPGV-------GVAPGVGLA--PGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAA 513 PG+ GV VG+ PG+ PG G VG +GP G Sbjct: 1122 RRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQG 1181 Query: 514 KVAAKAQLRAAAGLG-------------AGIPGLGVGVGVPGL--GVGA-GVPGLGVGAG 557 ++ G+G AG PG G+PG +G G G AG Sbjct: 1182 PTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAG 1241 Query: 558 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI---------PGGVVGAGPAAAA 608 PG PG AK + +PG LG G G GI PG V G GP A+ Sbjct: 1242 PPGKKGPPGE-DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGAS 1300 Query: 609 AAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGI--PPAAAAKAAKYGAAGLG 664 A + G G G G G G PG G G P A + G GL Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR 1360 Query: 665 GVLGGAGQFPLGGVAARPGFGLSPIFPGG 693 G+ G G+ L G + G P+ P G Sbjct: 1361 GIPGPVGEPGLLGAPGQMG-PPGPLGPSG 1388 Score = 132 bits (332), Expect = 1e-30 Identities = 224/742 (30%), Positives = 267/742 (35%), Gaps = 108/742 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGL-- 79 P P G+ G P G PG V G +G GA G G P P G G GL Sbjct: 510 PQGPRGLQG--PHGPPGRV-------GKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPG 560 Query: 80 -----GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGA 134 G F V PG PG D + G G PG GL G+ P Sbjct: 561 EKGQRGDFGHVGQPGP--PG--EDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRP 616 Query: 135 GVK-----PGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGVPTGAGVKPKAPGV 182 GV PG VG PG PG PG + PG L G P G P PG+ Sbjct: 617 GVTGIDGAPGAKGNVGPPGE-PGP--PGQQGNHGSQGLPGPQGLIGTPGEKG-PPGNPGI 672 Query: 183 GGAFAGIPGV-GPFGGPQPGVPLGY------PIKA--PKLPGGYGLPYTTGK-------- 225 G+PG GP G P P G P A P PG G+ T+G Sbjct: 673 ----PGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKG 728 Query: 226 ------LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVG 278 P G G+ G GK G P G GP+ A +A + G+AG +G Sbjct: 729 EKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLG 788 Query: 279 GAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG 338 G+PG PG PG G +G P K+ K G GP G G PG Sbjct: 789 VPGLPGYPGR-PGPKG--SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPG 845 Query: 339 A-GVPG----VGVPGAGIPVVPG-AGIPG----AAVPGVVSPEAAAKAAAKAAKYGARPG 388 A G PG VG GA P +PG G+PG PG P + G R Sbjct: 846 ATGQPGPKGDVGQDGA--PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903 Query: 389 VGVGGIPTYGVGAGGF--PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 446 +G G T G G P G G G G PG G PG G+PG+ E + A Sbjct: 904 LGFQG-QTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL----EGREGAK 958 Query: 447 AKAAKYGLVPGVGVAPGVGVAPGVGVAPG----VGLAPGVGVAPGVGVAPGVGVAPGIGP 502 + G + G A G+ PG PG GL G VG G +GP Sbjct: 959 GELGPPGPLGKEGPA-GLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017 Query: 503 -GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 561 GG+ +S ++ + + G PG G+PG G PG +G G Sbjct: 1018 AGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGD 1077 Query: 562 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 621 GA K +K G G G G GI G GP A A FG Sbjct: 1078 KGDVGA-PGHKGSK------GDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFG 1130 Query: 622 LVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAAR 681 G G+ G VG +G PG+ GL G PP + G+ G G G G G Sbjct: 1131 QKGDDGVRGF-VGVIGPPGLQGLPG-PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGT 1188 Query: 682 PGFGLSPIFPGGACLGKACGRK 703 PG PGG A G K Sbjct: 1189 PG------LPGGVGQPGAVGEK 1204 Score = 129 bits (323), Expect = 1e-29 Identities = 223/744 (29%), Positives = 260/744 (34%), Gaps = 132/744 (17%) Query: 28 GVPGAIPG-----GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 GVPG +PG G G + +PG LG +G G GK +P G G G Sbjct: 788 GVPG-LPGYPGRPGPKGSIGFPGP-LGPIG--EKGKSGKTGQPGLEGERGPPGSRGERGQ 843 Query: 83 PAVTF-PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG--------------------- 120 P T PG G D A K GL G PG G Sbjct: 844 PGATGQPGPKGDVG-QDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRG 902 Query: 121 -LGVSAGAVVPQPGAGVKP-GKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-- 176 LG P P + P GK VG G PG PG LPG+ G K Sbjct: 903 ELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGP--PGEQGLPGLEGREGAKGE 960 Query: 177 --PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGY--------PIKAPKLPG---------G 216 P P AG+ G GP GGP P G P+ A PG G Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGG 1020 Query: 217 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG----------VGPQAAAAAAAKAAAKF 266 GLP +G GP G G+ G+ G P TG +GP AA + + K Sbjct: 1021 IGLPGQSGS-EGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKG 1079 Query: 267 GAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPG 325 GA G G G G PG PGI G AG G P A A +G G Sbjct: 1080 DVGAPGHKGSKGDKGDAGPPGQ-PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD--DG 1136 Query: 326 GPGFGPGVVGVPGA-GVPG-------------VGVPGAGIPVVPGAGIPGAAVPGVVSPE 371 GF GV+G PG G+PG +G GA P P PG+ P Sbjct: 1137 VRGF-VGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGL--PG 1193 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG 431 + A K G R G G P GA G PG G G G +G G G PG G Sbjct: 1194 GVGQPGAVGEK-GERGDAGDPGPP----GAPGIPG-PKGDIGEKGDSGPSGAAGPPGKKG 1247 Query: 432 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 491 PG + A GL PG PG G+ +PG PG PG Sbjct: 1248 PPG-------EDGAKGSVGPTGL-PGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPG---P 1296 Query: 492 PGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGV 549 PG PG GP G + + + + A G G PG +G G G Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356 Query: 550 PGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 609 GL G+PG PG L A PG +G G LG G+PG GP Sbjct: 1357 EGL---RGIPGPVGEPGLLGA----------PGQMGPPGPLGPSGLPGLKGDTGPKGEKG 1403 Query: 610 AAKAAAKAAQFGLVGAAGLGGL-GV-------GGLGVPG-VGGLGGI-PPAAAAKAAKYG 659 G G G GL GV G G PG +G LG PP A + G Sbjct: 1404 HIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463 Query: 660 AAGLGGVLGGAGQFPLGGVAARPG 683 + G G +G G G PG Sbjct: 1464 SKGSPGSMGPRGDTGPAGPPGPPG 1487 Score = 129 bits (323), Expect = 1e-29 Identities = 195/629 (31%), Positives = 230/629 (36%), Gaps = 87/629 (13%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 HP + G G G P GV P G +G G GP G P P GL G L Sbjct: 897 HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPG--LEGR 954 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQ--PGAGV 136 GA + PG L G A + K G G G G+ G G V PG Sbjct: 955 EGAKGELGPPGPLGKEGPA-GLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERG 1013 Query: 137 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPF 195 G G+GLPG G+ P V P G+ + PG G GIPG +GP Sbjct: 1014 PLGPAGGIGLPGQ------SGSEGP---VGPAGKKGSRGERGPPGPTGK-DGIPGPLGPL 1063 Query: 196 GGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQ 253 G P P G + PG G G GP G G G AG+P GP Sbjct: 1064 GPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDA----GPPGQPGIRGPAGHP-----GPP 1114 Query: 254 AAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGVGTPAAAAAAAAAA 311 A A + G G+ G GV G G I PG+ G+ G P Sbjct: 1115 GADGAQGRR------GPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG--PPGEKGEVGDVG 1166 Query: 312 KAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG-VGVPG----AGIPVVPGA-GIPGA-- 362 +GA P GP G G+PG G PG VG G AG P PGA GIPG Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226 Query: 363 --AVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 417 G P AA K + GA+ VG G+P +G G PG G+ G PG Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG-DLGPPGDPGVS-GIDGSPGE 1284 Query: 418 AGVPG-VGGV--PGVGGVPGVGISP--------------EAQAAAAAKAAKYGLVPGVGV 460 G PG VGG PG G PG P E + A + G PG Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDG-PPGRTG 1343 Query: 461 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKA 519 G PG G+ PG PG+ APG PG +GP G+ K Sbjct: 1344 PMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKG 1403 Query: 520 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 579 + G+ GL +G PG G GL G PG PG + + Sbjct: 1404 HI--------GLIGL---IGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP 1452 Query: 580 VPGVLGGLGALGGVGIPGGVVGAGPAAAA 608 PGV G LG G G PG + G A Sbjct: 1453 -PGVAGPLGQKGSKGSPGSMGPRGDTGPA 1480 Score = 124 bits (310), Expect = 4e-28 Identities = 220/751 (29%), Positives = 257/751 (34%), Gaps = 143/751 (19%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALG-GGALGPGGKPLKPVPGGLAGA-GLGAGLGAFPAV 85 G PGA PG P G P G G G GP G + G+ G G G ++ Sbjct: 749 GKPGA-PG--PRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSI 805 Query: 86 TFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGV 144 FPG L P G K+ K G GL G G G G QPGA +PG V Sbjct: 806 GFPGPLGPIGEKG-----KSGKTGQPGLEGERGPPGSRGERG----QPGATGQPGPKGDV 856 Query: 145 GLPGVYPGGVLPGAR-FPGVGVLPGVP--------TGAGVKPKAPGVGGAFA-----GIP 190 G G PG +PG + PG+ PG P G +P PG G G P Sbjct: 857 GQDGA-PG--IPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPP 913 Query: 191 GVGPFGGPQPGV----PLGY--PIKAPKLPGGYGLPYTTG----KLPYGY-GPGGVAGAA 239 G GPQ PLG P P PG GLP G K G GP G G A Sbjct: 914 GPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPA 973 Query: 240 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVG 299 G G+P GP+ K G G VG G PG G + G G+G Sbjct: 974 GLRGFP-----GPKGGPGDPGPTGLKGDKGPPGP---VGANGSPGERGPL---GPAGGIG 1022 Query: 300 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGV------VGVPGAGVPG--------VG 345 P + + A K G+ P GP G+ +G PGA P VG Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082 Query: 346 VPG----------AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 395 PG AG P PG P A PG + A +G + GV G Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGP-AGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGF- 1140 Query: 396 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 455 VG G PG G+ G PG G G G G G PG P GL Sbjct: 1141 ---VGVIGPPGLQ-GLPGPPGEKGEVGDVGSMGPHGAPG----PRGPQGPTGSEGTPGLP 1192 Query: 456 PGVGVAPGVGVA--------PGVGVAPGV-GLAPGVGVAPGVGVAPGVGVAPGIGPGGVA 506 GVG VG PG APG+ G +G G + G GP G Sbjct: 1193 GGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGED 1252 Query: 507 AAAKSAAKVAAKAQLRAAAGLGA----------GIPGLGVGVGVPGLGVGAGVPG----- 551 A S L G G PG G G PG G PG Sbjct: 1253 GAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKR 1312 Query: 552 -----LG-------VGA-GVPGFGAVPGAL----AAAKAAKYGA----AVPGVLGG---L 587 +G GA G PG PG A + G +PG +G L Sbjct: 1313 GPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLL 1372 Query: 588 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGLGVPGVGGLG 645 GA G +G PG + +G + GL+G G G G G+PGV G Sbjct: 1373 GAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPP 1432 Query: 646 GI-----PPAAAAKAAKYGAAGLGGVLGGAG 671 G PP G G+ G LG G Sbjct: 1433 GPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463 Score = 123 bits (308), Expect = 7e-28 Identities = 207/717 (28%), Positives = 248/717 (34%), Gaps = 107/717 (14%) Query: 43 YPGAG-LGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAA 101 +PGAG GA G A+ G+ + PG G+ G FPG P G A Sbjct: 369 FPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPA---- 424 Query: 102 AYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG-KVPGVGLPGVYPGGVLPGARF 160 GL G+PG+ G+ G V+ P K P V VL + Sbjct: 425 ---------GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQL 475 Query: 161 -----PGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIK--APKL 213 PG L G P G+ P PG+ G GP G P P G K P Sbjct: 476 SMKGPPGPVGLTGRPGPVGL-PGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGA 534 Query: 214 PGGYGLPYTTGK--------LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAK 265 G GLP TG LP G G G G G P G + A + Sbjct: 535 DGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQ 594 Query: 266 FG-AGAAGVLPGVGGAGVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYG--A 318 G G G+L G G G PG + GI G G VG P G Sbjct: 595 AGEPGPRGLLGPRGSPGPTGRPG-VTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653 Query: 319 AAGLV--PG--GPGFGPGVVGVPGAGVPGVGVPGAGIPV-VPGA-GIPGAA-VPGVVSPE 371 GL+ PG GP PG+ G+PG+ P +G PG P GA G PG+A PG P Sbjct: 654 PQGLIGTPGEKGPPGNPGIPGLPGSDGP-LGHPGHEGPTGEKGAQGPPGSAGPPGYPGPR 712 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTY--------GVGAGGFPG--------------FGV 409 + G + G G P + G G PG Sbjct: 713 GVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA 772 Query: 410 GVGGIPGVAGVPGVGGVPGVGGVPG-------VG----ISPEAQAAAAAKAAKYGL---- 454 G G PG AG G GVPG+ G PG +G + P + + K + GL Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGER 832 Query: 455 ----VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVA 506 G PG PG G APG+ PG PG+ PG GP G Sbjct: 833 GPPGSRGERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGFPGPKGPPGHQ 889 Query: 507 AAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 562 + +L G AG+ G G G G PG G PG Sbjct: 890 GKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG---PPGPPGEQ 946 Query: 563 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGL 622 +PG L + AK PG LG G G G PG G G G Sbjct: 947 GLPG-LEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGA 1005 Query: 623 VGAAG-LGGLG-VGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAG-QFPLG 676 G+ G G LG GG+G+PG G G P A K G G G G G PLG Sbjct: 1006 NGSPGERGPLGPAGGIGLPGQSGSEG-PVGPAGKKGSRGERGPPGPTGKDGIPGPLG 1061 Score = 84.7 bits (208), Expect = 3e-16 Identities = 145/498 (29%), Positives = 174/498 (34%), Gaps = 92/498 (18%) Query: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-------- 287 AG G G P G Q A G GV+ G G PG PG Sbjct: 372 AGEKGAKGEPAVIEKGQQFEGPPGAP-------GPQGVVGPSGPPGPPGFPGDPGPPGPA 424 Query: 288 AIPGIGGIAGV--------------------GTPAAAAAAAAAAKAAKYGAAAGLVPGGP 327 +PGI GI G+ G P + A A A + + PG Sbjct: 425 GLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPV 484 Query: 328 GF--GPGVVGVPGAGVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG 384 G PG VG+PG PG+ G GA P P G+ G P + K G Sbjct: 485 GLTGRPGPVGLPGH--PGLKGEEGAEGPQGP-RGLQGPHGP-----------PGRVGKMG 530 Query: 385 ARPGV-GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-----GIS 438 RPG G G+P G G GF G+ G+PG G G G G G PG Sbjct: 531 -RPGADGARGLPG-DTGPKGDRGFD-GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEG 587 Query: 439 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 498 P A + GL+ G +PG PGV G+ APG A G PG P Sbjct: 588 PPGPTGQAGEPGPRGLL-GPRGSPGPTGRPGV---TGIDGAPG---AKGNVGPPGEPGPP 640 Query: 499 G-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGL-----GVGA-GVP 550 G G G + + G G+PG +G PG GA G P Sbjct: 641 GQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPP 700 Query: 551 GLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPA 605 G G PG V G L K K PG G +G G G PG G Sbjct: 701 GSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGED 760 Query: 606 AAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGG 665 A +A + G G+AG G LGVPG+ G G P G+ G G Sbjct: 761 GPEGPKGQAGQAGEEGPPGSAG----EKGKLGVPGLPGYPGRP-------GPKGSIGFPG 809 Query: 666 VLGGAGQFPLGGVAARPG 683 LG G+ G +PG Sbjct: 810 PLGPIGEKGKSGKTGQPG 827 Score = 75.1 bits (183), Expect = 2e-13 Identities = 103/334 (30%), Positives = 117/334 (35%), Gaps = 42/334 (12%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALG--GGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G G G+PGGV PGA +G G G A PG +PG G G Sbjct: 1179 PQGPTGSEGT--PGLPGGVGQPGA-VGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG--GVPGVGGLGVSAGAVVPQPGAGVKP 138 A PG P G A + LG G PGV G+ S PG P Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS-------PGEKGDP 1288 Query: 139 GKVPGVGLPGVYPGGVLPGARFPGVGVLPGV--PTGAGVKPKAPGVGGAFA-----GIPG 191 G V G G PG PGA P PG P+G + G GA G PG Sbjct: 1289 GDVGGPGPPGASGE---PGAPGP-----PGKRGPSGHMGREGREGEKGAKGEPGPDGPPG 1340 Query: 192 -VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG- 249 GP G P +G P +PG G P G P GP G G +G G TG Sbjct: 1341 RTGPMGARGPPGRVG-PEGLRGIPGPVGEPGLLGA-PGQMGPPGPLGPSGLPGLKGDTGP 1398 Query: 250 ------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 303 +G +A K G GV G G PG PG IG + G P Sbjct: 1399 KGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP---IGSLGHPGPPGV 1455 Query: 304 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 337 A G+ GP PG G P Sbjct: 1456 AGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 68.9 bits (167), Expect = 1e-11 Identities = 101/357 (28%), Positives = 125/357 (35%), Gaps = 64/357 (17%) Query: 353 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 411 + PGAG GA P V+ E + G + VG G P G GFPG Sbjct: 368 IFPGAGEKGAKGEPAVI--EKGQQFEGPPGAPGPQGVVGPSGPP----GPPGFPGDP--- 418 Query: 412 GGIPGVAGVPGVGGVPGVGGVPG-VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 470 G PG AG+PG+ G+ G+ G PG V + P A + K A + Sbjct: 419 -GPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSM 477 Query: 471 GVAPG-VGLA--PG-VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 526 PG VGL PG VG+ G+ G GP G+ Sbjct: 478 KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP------------------ 519 Query: 527 LGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 586 G PG +G PG G+PG G GF +PG +PG G Sbjct: 520 --HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPG-------------LPGEKGQ 564 Query: 587 LGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 646 G G VG PG G A +A + G G G G G G PGV G+ G Sbjct: 565 RGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRG-SPGPTGRPGVTGIDG 623 Query: 647 IP-----------PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 P P + +G+ GL G G G G PG P PG Sbjct: 624 APGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI---PGLPG 677 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 142 bits (357), Expect = 1e-33 Identities = 228/764 (29%), Positives = 278/764 (36%), Gaps = 144/764 (18%) Query: 11 PGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA----GLGALGGGALGPGGKPLKPV 66 PG ++ S+ +P P G+ G + G PGG G GL A G +GP G P P Sbjct: 453 PGSSVIYCSVGNPG-PQGIKGKV--GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG 509 Query: 67 PGGLAG-AGLGAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPG-VG 119 G G GL LG PGA P G+ A K AK + V G G Sbjct: 510 RQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKG 569 Query: 120 GLGVSAGAVVP-QPGAGVKPGKVPGVGLPGVYPGG---VLPGAR-FPGVGVLPGVPTGAG 174 G P QPG+ + G G PG PG PG + FPG P P G Sbjct: 570 ERGPDGPPGFPGQPGSHGRDGHAGEKGDPGP-PGDHEDATPGGKGFPG----PLGPPGKA 624 Query: 175 VKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-LPGGYGLPYTTG-KLPYGYG 231 PG+G F G PG PGVP G+P ++ P L G G + P +G Sbjct: 625 GPVGPPGLG--FPGPPGERG----HPGVP-GHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677 Query: 232 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG---- 287 P G G G G+P GPQ A + K G G A +PG PG Sbjct: 678 PPGFDGPPGPKGFP-----GPQGAPGLSGSDGHKGRPGTPGT------AEIPGPPGFRGD 726 Query: 288 -AIPGIGGIAG---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----A 339 PG GG G VG P + + +PG P FG +G PG + Sbjct: 727 MGDPGFGGEKGSSPVGPPGPPGSPGVNGQKG--------IPGDPAFGH--LGPPGKRGLS 776 Query: 340 GVPGVGVPGAGIPVVPGA----GIPG-------------AAVPGVVSPEAAAKAAAKAAK 382 GVPG+ P G P PGA GIPG A PGV P + + Sbjct: 777 GVPGIKGP-RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG------HSCE 829 Query: 383 YGARPGV-GVGGIPTYGVGAGGFPGFG----------VGVGGIPGVAGVPGVGGVPGVGG 431 GA PG+ G G+P Y G G G G+ G+PG+ G PG G PG+ G Sbjct: 830 RGA-PGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPG 888 Query: 432 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 491 +PG + GL PG PG PG PG PG G+ Sbjct: 889 IPG-PFGDDGLPGPPGPKGPRGL-PGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGD 946 Query: 492 PGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----GIPGLGVGVGVPGLGVG 546 G+ A G IGP G ++A +Q G G PG G PG+ Sbjct: 947 RGLRGAKGAIGPPG------DEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGR 1000 Query: 547 AGVPGL----GVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG 597 G PG G G PG PG + + PG+ G G G G PG Sbjct: 1001 RGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPG 1060 Query: 598 --GVVGA--------------GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVP 639 G+ GA GP + FG G GL G+ G G P Sbjct: 1061 FSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRP 1120 Query: 640 GVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G G PP G G G +G G L G PG Sbjct: 1121 GPPGSSG-PPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPG 1163 Score = 140 bits (352), Expect = 5e-33 Identities = 241/816 (29%), Positives = 285/816 (34%), Gaps = 171/816 (20%) Query: 22 HPSRPG--GVPGAIP-GGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAG---L 75 HP PG G PG G G +PG G GALGPGG P G G L Sbjct: 126 HPGPPGPRGKPGMSGHNGSRGDPGFPG------GRGALGPGGPLGHPGEKGEKGNSVFIL 179 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGLGVSAGAVVPQ 131 GA G PG +PG A A G GL G PG G G Sbjct: 180 GAVKGIQGDRGDPG--LPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKG----N 233 Query: 132 PGAGVK-----PGKVPGVGLPG-----------VYPG--GVLPGARFPGVGVLPGVP--- 170 PG GVK PG+V G PG +Y G G+ PG+ LPG P Sbjct: 234 PGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGI---KGIPGMVGLPGPPGRK 290 Query: 171 --TGAGVK--------------------PKAPGVGG--AFAGIPG----VGPFGGP---- 198 +G G K P PG+ G G PG +GP G P Sbjct: 291 GESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRG 350 Query: 199 ---QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAA 255 PGV + P+ PG G P G+ GP G G G+ G +GP Sbjct: 351 HPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG-DVGPPGPPGLLGRPGEACAGMIGPPGP 409 Query: 256 AAAAAKAAAKFGAGAAG---VLPG-VGGAGVPGVPGAIPGIGGIAG-------VGTPAAA 304 AG G PG G G PG+PGA PG+ G+ G VG P Sbjct: 410 QGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGA-PGLQGLPGSSVIYCSVGNPGPQ 468 Query: 305 AAAAAAAKAAKYGAAAGLVPGGP-------GFGPGVVGVPG-AGVPG-------VGVPG- 348 K G G P G PG +G PG G+PG +G+PG Sbjct: 469 GI------KGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGW 522 Query: 349 ---AGIPVVPGA----GIPG----AAVPG--------VVS----------PEAAAKAAAK 379 G P PGA G+PG + PG VVS P+ + Sbjct: 523 LGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQ 582 Query: 380 AAKYGARPGVGVGGIP-------TYGVGAGGFPGFGVGVGGIPGVAGVPGVG--GVPGVG 430 +G G G P G GFPG +G G G G PG+G G PG Sbjct: 583 PGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPG-PLGPPGKAGPVGPPGLGFPGPPGER 641 Query: 431 GVPGVGISPEAQAAAAAKAAKYGLV------PGVGVAPGVGVAPGVGVAPGVGLAPGVGV 484 G PGV P + K K + PG PG PG PG APG+ Sbjct: 642 GHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSG 701 Query: 485 APGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL 543 + G PG G A GP G K G PG+ G+PG Sbjct: 702 SDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGD 761 Query: 544 GV--GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 601 G PG +GVPG P A+ A +PG LG G G G G Sbjct: 762 PAFGHLGPPGKRGLSGVPGIKG-PRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGV 820 Query: 602 AGPAAAAAAAKAAAKAAQFGLVGAAGL----GGLG-VGGLGVPGVGGLGGIPPAAAAKAA 656 GP + A Q GL G G GG G G +G PG G+ G+ P + Sbjct: 821 PGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL-PGLPGRPG 879 Query: 657 KYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 +G GL G+ G G L G G P FPG Sbjct: 880 AHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPG 915 Score = 132 bits (331), Expect = 1e-30 Identities = 235/814 (28%), Positives = 277/814 (34%), Gaps = 189/814 (23%) Query: 22 HPSRPGGVPGA--IPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKP-------VPGGL 70 H RPG PG IPG G G + PG G G G +GP G P P +PG Sbjct: 705 HKGRPG-TPGTAEIPGPPGFRGDMGDPGFG-GEKGSSPVGPPGPPGSPGVNGQKGIPGDP 762 Query: 71 AGAGLGA----GLGAFPAVT-------FPGALVPGGVAD--AAAAYKAAKAGAGLGGVPG 117 A LG GL P + PGA P G+ K + AG GVPG Sbjct: 763 AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPG 822 Query: 118 VGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP----GVGVLPGVP--T 171 G GA PG +PG G PG G PG P G+ LPG+P Sbjct: 823 PPGHSCERGA----PGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRP 878 Query: 172 GAGVKPKAPGVGGAFA--GIPGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPYTTGK-- 225 GA P PG+ G F G+PG GP+ PG P G+P + K PG G P G+ Sbjct: 879 GAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP-GFPGERGK-PGAEGCPGAKGEPG 936 Query: 226 ------LPYGYGPGGVAGAAGKAGYPTGTGV-------------GPQAAAAAAAKAAAK- 265 LP G G+ GA G G P G GP + K Sbjct: 937 EKGMSGLP---GDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993 Query: 266 ------------------FGAGAAGVLPGVGGAGVPGVPGA--------IPGIGGIAGV- 298 F G G G G PG PG+ PG+ G G Sbjct: 994 TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEP 1053 Query: 299 GTPA----AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------AGVPGV--- 344 G+P + A K K A+ P GP PG G PG G+PG+ Sbjct: 1054 GSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGP 1113 Query: 345 -------GVPGA-GIPVVPG-------------------------AGIPGAAVPGVVSPE 371 G PG+ G P PG GIPG PG+ P Sbjct: 1114 RGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP--PGIKGPS 1171 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFGVGVGGIPGVAGV--PGVGGVPG 428 + G + G G+ G G G PG G G PG G+ PG G G Sbjct: 1172 GSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK-GERGDPGSPGISPPGPRGKKG 1230 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG----VGV 484 G PG P A A +A K PG G G APG PG + Sbjct: 1231 PPGPPGSS-GPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG 1289 Query: 485 APGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 542 PG PG PG GP G K K + G G PG G+PG Sbjct: 1290 EPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPG 1349 Query: 543 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA 602 PG G+PG PG A +PG G G G +G+PG + Sbjct: 1350 ------PPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPS 1403 Query: 603 GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAG 662 GP G G GL G GV GV G G P + G G Sbjct: 1404 GP----------------GCKGEPGLD----GRRGVDGVPGSPGPP-------GRKGDTG 1436 Query: 663 LGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 696 G GG G P G + G P + GG L Sbjct: 1437 EDGYPGGPG--PPGPIGDPGPKGFGPGYLGGFLL 1468 Score = 111 bits (278), Expect = 2e-24 Identities = 208/706 (29%), Positives = 243/706 (34%), Gaps = 124/706 (17%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G+ GP G P P G GA GL + G P G AA K K G+ Sbjct: 62 GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMR--GDRGPPG----AAGDKGDKGPTGVP 115 Query: 114 GVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA 173 G PG+ G+ G P+ G+ G G PG +PGG GA PG G L G P Sbjct: 116 GFPGLDGIPGHPGPPGPRGKPGMS-GHNGSRGDPG-FPGG--RGALGPG-GPL-GHPGEK 169 Query: 174 GVKPKAPGVGGAFAGIPG----------VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTT 223 G K + + GA GI G G +G P P GYP + PG G P Sbjct: 170 GEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGE----PGLVGPPGQP 225 Query: 224 GKLPYGYGPG-GVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAG 281 G+ PG GV G G G G GP K G G+ PG+ G Sbjct: 226 GRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGI-PGM--VG 282 Query: 282 VPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAA--------GLV--PG-----G 326 +PG PG G GI G YG+ GLV PG G Sbjct: 283 LPGPPGR-KGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIG 341 Query: 327 PGFGPGVVGVPGA------------GVPG-VGVPG-------AGIPVVPGA-GIPGAAVP 365 P PG G PG G PG G PG G P PG G PG A Sbjct: 342 PKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACA 401 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G++ P G + G+ G+P G G PG G PG G PG+ G Sbjct: 402 GMIGPP------------GPQGFPGLPGLP----GEAGIPGRPDSAPGKPGKPGSPGLPG 445 Query: 426 VPGVGGVPG-------VG----------ISPEAQAAAAAKAAKYGLV---PGVGVAPGVG 465 PG+ G+PG VG + P + GL PG PG Sbjct: 446 APGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPP 505 Query: 466 VAPG-VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 524 PG G +GL +G G PG PG+ PG A+ K AK + Sbjct: 506 GLPGRQGSKGDLGLPGWLGTKGDPG-PPGAEGPPGL-PGKHGASGPPGNK-GAKGDM--V 560 Query: 525 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 584 G G G PG G G AG G PG A G PG L Sbjct: 561 VSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPG--DHEDATPGGKGFPGPL 618 Query: 585 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV-------GGLG 637 G G G VG P G+ GP G G G G + G G Sbjct: 619 GPPGKAGPVG-PPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677 Query: 638 VPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 PG G PP GA GL G G G+ G A PG Sbjct: 678 PPGFDG----PPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPG 719 Score = 99.8 bits (247), Expect = 8e-21 Identities = 146/497 (29%), Positives = 177/497 (35%), Gaps = 106/497 (21%) Query: 192 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVG 251 +GP GG V P K G G P GP G G G G P G Sbjct: 44 IGPCGGRDCSVCHCVPEK-----GSRGPP----------GPPGPQGPIGPLGAP-----G 83 Query: 252 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGV-GTPAAAAAAA 308 P + + GAAG G GVPG PG IPG G G G P + Sbjct: 84 PIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNG 143 Query: 309 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV 368 + G L PGGP PG G G V +G AV G+ Sbjct: 144 SRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILG-----------------AVKGI- 185 Query: 369 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 428 G R G+ G+P GAGG P G G PG+ G PG G PG Sbjct: 186 --------------QGDRGDPGLPGLPG-SWGAGG-PAGPTGYPGEPGLVGPPGQPGRPG 229 Query: 429 VGGVPGVGISPEAQAAAAAKAAKYGLV-PGVGVAP----------GVGVAPGVGVAPGVG 477 + G PGVG+ + Q + + G P + V P G+ PG+ PG Sbjct: 230 LKGNPGVGV--KGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPG-- 285 Query: 478 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG 537 PG G+G G+ GP G + S K +L GL G PGL Sbjct: 286 -PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGEL----GL-VGDPGLFGL 339 Query: 538 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIP 596 +G G G PG PG L G PG G G G VG P Sbjct: 340 IGPKGDPGNRGHPG------------PPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPP 387 Query: 597 G--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 654 G G++G A A G++G G G G G+PG G+ G P +A K Sbjct: 388 GPPGLLGRPGEACA------------GMIGPPGPQGF-PGLPGLPGEAGIPGRPDSAPGK 434 Query: 655 AAKYGAAGLGGVLGGAG 671 K G+ GL G G G Sbjct: 435 PGKPGSPGLPGAPGLQG 451 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 140 bits (352), Expect = 5e-33 Identities = 234/784 (29%), Positives = 273/784 (34%), Gaps = 159/784 (20%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 587 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 643 Query: 70 LAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 + G G P P G L P G A G G+ GV G G + Sbjct: 644 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP----------GQPGMAGVDGPPGPKGNM 693 Query: 129 VPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVG 183 PQ PG + G GLPG P G + PG + P G L G+P GA P PG Sbjct: 694 GPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPGHPGKE 750 Query: 184 GAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGG 234 G +GP P P P+GYP P+ G GL + G+ P G G Sbjct: 751 GQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805 Query: 235 VAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 + G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 806 LKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP--------------------GFGP- 331 G G P A A A K G P GP G GP Sbjct: 865 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 924 Query: 332 ------------GVVGVPG-AGVPGV----GVPG-------AGIPVVPGAGIPGAAV--- 364 G VG PG G PG G+PG G G PG V Sbjct: 925 GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 984 Query: 365 --------------PGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG--GFPGFG 408 PG P A K GA+ G GI AG GFP Sbjct: 985 GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFP--- 1041 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAP 468 G G+PG G PG+ G G G PG SP + +A A GL PG PG P Sbjct: 1042 -GERGLPGAQGAPGLKGGEGPQGPPGPVGSP-GERGSAGTAGPIGL-PG---RPGPQGPP 1095 Query: 469 GVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 524 G G APG G A GV VG+ GP G ++ Q + Sbjct: 1096 GPAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1152 Query: 525 AGLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGALAAA 571 G G PGL VG PG+ G G PG G+ G GF PG + Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212 Query: 572 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 631 PG G G +G +G PG GP A G VG G G Sbjct: 1213 GL----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268 Query: 632 --GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 689 G G PG G+GG P + + G G G G G G PG P+ Sbjct: 1269 PGEAGNPGPPGEAGVGG-PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG----PV 1323 Query: 690 -FPG 692 FPG Sbjct: 1324 GFPG 1327 Score = 134 bits (337), Expect = 3e-31 Identities = 218/704 (30%), Positives = 236/704 (33%), Gaps = 96/704 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPG-----AGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGL 79 P G PG P G GG PG G G G GP G P P GL G G Sbjct: 908 PTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 965 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 F T P PGGV G G PG G G PGA K G Sbjct: 966 TGFQGKTGPPG--PGGVVGPQGP-TGETGPIGERGHPGPPGPPGEQGL----PGAAGKEG 1018 Query: 140 KVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 G G+ G R FPG LPG APG+ G GP G P Sbjct: 1019 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG-------APGLKGGEGPQGPPGPVGSP 1071 Query: 199 QPGVPLGY--PIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQA 254 G PI P PG G P G+ P GP G AG G G P G GP Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG-PVGLP-GPAG 1129 Query: 255 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAA 314 A + + K G G G G G PG PG+ G VG P A Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQG--PVGAPGIAGGDGEPGPRG 1186 Query: 315 KYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GVPGAGIPVVPGAGIPGAAVP-GVVSPE 371 + G G PG G G G+PG G G V P G PG P G P Sbjct: 1187 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP-MGPPGPPGPRGPQGPN 1245 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGV 429 A G+ GVG G P G G PG GVGG G G G G PG Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEP----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301 Query: 430 GGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 487 G PG P G PG PG GVG G PG PG Sbjct: 1302 AGPPGAK-GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360 Query: 488 VGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGLGV 536 G PG GP G A A + AK + A G AG PG Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1420 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 596 G+PG G+PG G PG PG +PG+ G G+ G G P Sbjct: 1421 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPG-------------LPGLKGDPGSKGEKGHP 1467 Query: 597 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI--------P 648 G + GP G G G GL G G PG G GGI P Sbjct: 1468 GLIGLIGPP---------------GEQGEKGDRGLP-GTQGSPGAKGDGGIPGPAGPLGP 1511 Query: 649 PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 P G G G G AGQ G+ PG SP PG Sbjct: 1512 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG---SPGPPG 1552 Score = 128 bits (321), Expect = 2e-29 Identities = 199/636 (31%), Positives = 224/636 (35%), Gaps = 72/636 (11%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 959 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1014 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 G A PG P G++ D A + GL G G GL G P PG Sbjct: 1015 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP-PGPVGS 1070 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG+ G G P G LPG PG PG P G P G G AG GV GP G Sbjct: 1071 PGERGSAGTAG--PIG-LPGR--PGPQGPPG-PAGEKGAPGEKGPQGP-AGRDGVQGPVG 1123 Query: 197 GPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 P P P G P I P G G G GP G+ G G G G Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPGIAGGD 1179 Query: 249 GV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVP 365 G P GP PG VG G GV G PG AG P PG AG+ G Sbjct: 1240 GPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVGGPK-- 1287 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G + A A GA+ G G P G GFPG G G PG AG GVGG Sbjct: 1288 GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQDGVGG 1345 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 485 G G PG P A PG PG A G G G Sbjct: 1346 DKGEDGDPGQPGPPGPSGEAGPPGP-----PGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400 Query: 486 PG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-----GIPGLGVGVG 539 PG G G A GP G+ + + L AAG G PGL G Sbjct: 1401 PGKTGPVGPQGPAGKPGPEGL----RGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1456 Query: 540 VPGLGVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVG 594 PG G PGL G PG G + AK +PG G LG G G Sbjct: 1457 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPG 1516 Query: 595 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 630 +PG GP + A + GL G G G Sbjct: 1517 LPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549 Score = 115 bits (288), Expect = 1e-25 Identities = 209/702 (29%), Positives = 243/702 (34%), Gaps = 110/702 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 458 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 506 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 + G G A A A +A L G PG GL +PG Sbjct: 507 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG-------------RPG 553 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 V G G G PG + P GV PG PTG K PG G G+PG G Sbjct: 554 PVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEPGAKGD 611 Query: 199 Q-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + PG+P G+ P P PG G+ G++ GP G+ G AG G Sbjct: 612 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGL-- 665 Query: 247 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAA 304 +GP+ A + G G +G G PG PG PG G+ G P Sbjct: 666 ---LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 722 Query: 305 AAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGA-GIP 360 PG GP PG+ G+PGA P G PG G GA G P Sbjct: 723 -------------------PGEKGPQGKPGLAGLPGADGP-PGHPGKEGQSGEKGALGPP 762 Query: 361 GAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY--GVGAGGFPGFGVGVGGIPGV 417 G P G P A G++ G G P + +G G G VG G G Sbjct: 763 GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG-EVGQIGPRGE 821 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G G G G G PG P QA K VPG+ PG G PG Sbjct: 822 DGPEGPKGRAGPTGDPG----PSGQAGEKGKLG----VPGLPGYPGRQGPKGSTGFPGFP 873 Query: 478 LAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 536 A G A GV PG G GP G A K K G G PG Sbjct: 874 GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK-----GTSGGDGPPGPPG 928 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYGAAVPGVL----GGLG 588 G G G PG G PG +PG K G PG + G G Sbjct: 929 ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 988 Query: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGG 646 G +G G GP AA K G G G+ G G GL G PG GL G Sbjct: 989 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 1048 Query: 647 IPPAAAAKAAK-----YGAAGLGGVLGGAGQFPLGGVAARPG 683 A K + G G G G AG G+ RPG Sbjct: 1049 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1090 Score = 97.8 bits (242), Expect = 3e-20 Identities = 145/522 (27%), Positives = 180/522 (34%), Gaps = 102/522 (19%) Query: 177 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 232 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G PT + Q A A A A+ + G PG + Sbjct: 514 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 549 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 348 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 607 Query: 349 A-------GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 A G+P +PG G P+ G +G G+P G Sbjct: 608 AKGDRGFDGLPGLPG----DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP----GE 659 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 461 G G +G G PG G PG+ GV G G G + P+ + PG Sbjct: 660 AGPRGL-LGPRGTPGAPGQPGMAGVDGPPGPKG-NMGPQGEPGP----------PGQQGN 707 Query: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 521 PG PG G G PG+ PG PG PG + + A Sbjct: 708 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGA-------- 758 Query: 522 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 581 G PG +G PG GV G V G L +K K P Sbjct: 759 -------LGPPGPQGPIGYPG------------PRGVKGADGVRG-LKGSKGEKGEDGFP 798 Query: 582 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 641 G G +G G G G + GP +A G G +G G G LGVPG+ Sbjct: 799 GFKGDMGLKGDRGEVGQI---GPRGEDGPEGPKGRAGPTGDPGPSGQAG-EKGKLGVPGL 854 Query: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G + G+ G G G G+ GVA +PG Sbjct: 855 PGYPG-------RQGPKGSTGFPGFPGANGEKGARGVAGKPG 889 Score = 92.0 bits (227), Expect = 2e-18 Identities = 160/519 (30%), Positives = 179/519 (34%), Gaps = 119/519 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA----------GL 75 PG G P G PG V PG A G +G G+P P G AG G Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1112 Query: 76 GAGLGAFPAVTFPGALVPGGVAD--------AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 127 G V PG P G K +K G G PG GL GA Sbjct: 1113 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172 Query: 128 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG G+ G G++ GAR FPG P P G P PG G Sbjct: 1173 ----PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG----PPGPIGLQGLPGPPGEKGEN 1224 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + +GP G P P P G P A G G P + G + G G G G AG G P Sbjct: 1225 GDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPGPPG 1279 Query: 247 GTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV-------------- 273 GVG P AA AK K G G Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339 Query: 274 LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGAAAG 321 GVGG G PG PG PG G AG P AA A K AK A A Sbjct: 1340 QDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1398 Query: 322 LVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA-GIP 360 PG G GP G G PG G+PG G+PGA G P +PG G P Sbjct: 1399 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1458 Query: 361 GA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFPGF- 407 G+ + G++ P E K PG G GGIP +G G PG Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1518 Query: 408 -------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G+ G PG G PG I P Sbjct: 1519 GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557 Score = 62.4 bits (150), Expect = 1e-09 Identities = 95/329 (28%), Positives = 113/329 (34%), Gaps = 32/329 (9%) Query: 387 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGV------- 435 PG+ V G P AG G PG G G PG G PG G+PG G+PG Sbjct: 448 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 507 Query: 436 -----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 490 G + +A +A ++ +A + PG G+ PG PG Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIA--LRGPPG---PMGLTGRPGPVGGPGSSG 562 Query: 491 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 549 A G PG GP GV K + R A G G+PG G G G+ Sbjct: 563 AKGESGDPGPQGPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGFDGLPGL 620 Query: 550 PGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 604 PG G G PG + +PG G G LG G PG G Sbjct: 621 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680 Query: 605 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLG 664 A G G G G G G+PG G G PP K G AGL Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKPGLAGLP 738 Query: 665 GVLGGAGQFPLGGVAARPGFGLSPIFPGG 693 G G G G + G L P P G Sbjct: 739 GADGPPGHPGKEGQSGEKG-ALGPPGPQG 766 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 140 bits (352), Expect = 5e-33 Identities = 234/784 (29%), Positives = 273/784 (34%), Gaps = 159/784 (20%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 536 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592 Query: 70 LAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAV 128 + G G P P G L P G A G G+ GV G G + Sbjct: 593 MRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP----------GQPGMAGVDGPPGPKGNM 642 Query: 129 VPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPKAPGVG 183 PQ PG + G GLPG P G + PG + P G L G+P GA P PG Sbjct: 643 GPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPGHPGKE 699 Query: 184 GAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYGYGPGG 234 G +GP P P P+GYP P+ G GL + G+ P G G Sbjct: 700 GQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754 Query: 235 VAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 + G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 755 LKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGP--------------------GFGP- 331 G G P A A A K G P GP G GP Sbjct: 814 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873 Query: 332 ------------GVVGVPG-AGVPGV----GVPG-------AGIPVVPGAGIPGAAV--- 364 G VG PG G PG G+PG G G PG V Sbjct: 874 GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933 Query: 365 --------------PGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG--GFPGFG 408 PG P A K GA+ G GI AG GFP Sbjct: 934 GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFP--- 990 Query: 409 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAP 468 G G+PG G PG+ G G G PG SP + +A A GL PG PG P Sbjct: 991 -GERGLPGAQGAPGLKGGEGPQGPPGPVGSP-GERGSAGTAGPIGL-PG---RPGPQGPP 1044 Query: 469 GVGVAPGVGLAPG----VGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAA 524 G G APG G A GV VG+ GP G ++ Q + Sbjct: 1045 GPAGEKG---APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101 Query: 525 AGLG----AGIPGLGVGVGVPGLGVGAGVPG----LGV-----GAGVPGFGAVPGALAAA 571 G G PGL VG PG+ G G PG G+ G GF PG + Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161 Query: 572 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 631 PG G G +G +G PG GP A G VG G G Sbjct: 1162 GL----PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217 Query: 632 --GVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPI 689 G G PG G+GG P + + G G G G G G PG P+ Sbjct: 1218 PGEAGNPGPPGEAGVGG-PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPG----PV 1272 Query: 690 -FPG 692 FPG Sbjct: 1273 GFPG 1276 Score = 134 bits (337), Expect = 3e-31 Identities = 218/704 (30%), Positives = 236/704 (33%), Gaps = 96/704 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPG-----AGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGL 79 P G PG P G GG PG G G G GP G P P GL G G Sbjct: 857 PTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE 914 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 F T P PGGV G G PG G G PGA K G Sbjct: 915 TGFQGKTGPPG--PGGVVGPQGP-TGETGPIGERGHPGPPGPPGEQGL----PGAAGKEG 967 Query: 140 KVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 G G+ G R FPG LPG APG+ G GP G P Sbjct: 968 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQG-------APGLKGGEGPQGPPGPVGSP 1020 Query: 199 QPGVPLGY--PIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQA 254 G PI P PG G P G+ P GP G AG G G P G GP Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG-PVGLP-GPAG 1078 Query: 255 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAA 314 A + + K G G G G G PG PG+ G VG P A Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP-PGLQG--PVGAPGIAGGDGEPGPRG 1135 Query: 315 KYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GVPGAGIPVVPGAGIPGAAVP-GVVSPE 371 + G G PG G G G+PG G G V P G PG P G P Sbjct: 1136 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP-MGPPGPPGPRGPQGPN 1194 Query: 372 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG--FGVGVGGIPGVAGVPGVGGVPGV 429 A G+ GVG G P G G PG GVGG G G G G PG Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEP----GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250 Query: 430 GGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 487 G PG P G PG PG GVG G PG PG Sbjct: 1251 AGPPGAK-GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309 Query: 488 VGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG----------AGIPGLGV 536 G PG GP G A A + AK + A G AG PG Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEG 1369 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIP 596 G+PG G+PG G PG PG +PG+ G G+ G G P Sbjct: 1370 LRGIPGPVGEQGLPGAAGQDGPPGPMGPPG-------------LPGLKGDPGSKGEKGHP 1416 Query: 597 GGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGI--------P 648 G + GP G G G GL G G PG G GGI P Sbjct: 1417 GLIGLIGPP---------------GEQGEKGDRGLP-GTQGSPGAKGDGGIPGPAGPLGP 1460 Query: 649 PAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPG 692 P G G G G AGQ G+ PG SP PG Sbjct: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPG---SPGPPG 1501 Score = 128 bits (321), Expect = 2e-29 Identities = 199/636 (31%), Positives = 224/636 (35%), Gaps = 72/636 (11%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 908 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 963 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAGAVVPQPGAGVK 137 G A PG P G++ D A + GL G G GL G P PG Sbjct: 964 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGP-PGPVGS 1019 Query: 138 PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV-GPFG 196 PG+ G G P G LPG PG PG P G P G G AG GV GP G Sbjct: 1020 PGERGSAGTAG--PIG-LPGR--PGPQGPPG-PAGEKGAPGEKGPQGP-AGRDGVQGPVG 1072 Query: 197 GPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGT 248 P P P G P I P G G G GP G+ G G G G Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPGIAGGD 1128 Query: 249 GV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAA 307 G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188 Query: 308 AAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVP 365 G P GP PG VG G GV G PG AG P PG AG+ G Sbjct: 1189 GPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVGGPK-- 1236 Query: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGG 425 G + A A GA+ G G P G GFPG G G PG AG GVGG Sbjct: 1237 GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQDGVGG 1294 Query: 426 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 485 G G PG P A PG PG A G G G Sbjct: 1295 DKGEDGDPGQPGPPGPSGEAGPPGP-----PGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349 Query: 486 PG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-----GIPGLGVGVG 539 PG G G A GP G+ + + L AAG G PGL G Sbjct: 1350 PGKTGPVGPQGPAGKPGPEGL----RGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKG 1405 Query: 540 VPGLGVGAGVPGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVG 594 PG G PGL G PG G + AK +PG G LG G G Sbjct: 1406 DPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPG 1465 Query: 595 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 630 +PG GP + A + GL G G G Sbjct: 1466 LPG---PQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498 Score = 115 bits (288), Expect = 1e-25 Identities = 209/702 (29%), Positives = 243/702 (34%), Gaps = 110/702 (15%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 407 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 455 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAGAVVPQPGAGVKPG 139 + G G A A A +A L G PG GL +PG Sbjct: 456 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG-------------RPG 502 Query: 140 KVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGP 198 V G G G PG + P GV PG PTG K PG G G+PG G Sbjct: 503 PVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEPGAKGD 560 Query: 199 Q-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + PG+P G+ P P PG G+ G++ GP G+ G AG G Sbjct: 561 RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGL-- 614 Query: 247 GTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVGTPAAA 304 +GP+ A + G G +G G PG PG PG G+ G P Sbjct: 615 ---LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGP 671 Query: 305 AAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPGA-GIP 360 PG GP PG+ G+PGA P G PG G GA G P Sbjct: 672 -------------------PGEKGPQGKPGLAGLPGADGP-PGHPGKEGQSGEKGALGPP 711 Query: 361 GAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY--GVGAGGFPGFGVGVGGIPGV 417 G P G P A G++ G G P + +G G G VG G G Sbjct: 712 GPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG-EVGQIGPRGE 770 Query: 418 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 477 G G G G G PG P QA K VPG+ PG G PG Sbjct: 771 DGPEGPKGRAGPTGDPG----PSGQAGEKGKLG----VPGLPGYPGRQGPKGSTGFPGFP 822 Query: 478 LAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGV 536 A G A GV PG G GP G A K K G G PG Sbjct: 823 GANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK-----GTSGGDGPPGPPG 877 Query: 537 GVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYGAAVPGVL----GGLG 588 G G G PG G PG +PG K G PG + G G Sbjct: 878 ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTG 937 Query: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL-GVPGVGGLGG 646 G +G G GP AA K G G G+ G G GL G PG GL G Sbjct: 938 ETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPG 997 Query: 647 IPPAAAAKAAK-----YGAAGLGGVLGGAGQFPLGGVAARPG 683 A K + G G G G AG G+ RPG Sbjct: 998 AQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1039 Score = 97.8 bits (242), Expect = 3e-20 Identities = 145/522 (27%), Positives = 180/522 (34%), Gaps = 102/522 (19%) Query: 177 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 232 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 233 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 292 G G PT + Q A A A A+ + G PG + Sbjct: 463 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 498 Query: 293 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 348 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 556 Query: 349 A-------GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 A G+P +PG G P+ G +G G+P G Sbjct: 557 AKGDRGFDGLPGLPG----DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP----GE 608 Query: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 461 G G +G G PG G PG+ GV G G G + P+ + PG Sbjct: 609 AGPRGL-LGPRGTPGAPGQPGMAGVDGPPGPKG-NMGPQGEPGP----------PGQQGN 656 Query: 462 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 521 PG PG G G PG+ PG PG PG + + A Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGA-------- 707 Query: 522 RAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVP 581 G PG +G PG GV G V G L +K K P Sbjct: 708 -------LGPPGPQGPIGYPG------------PRGVKGADGVRG-LKGSKGEKGEDGFP 747 Query: 582 GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGV 641 G G +G G G G + GP +A G G +G G G LGVPG+ Sbjct: 748 GFKGDMGLKGDRGEVGQI---GPRGEDGPEGPKGRAGPTGDPGPSGQAG-EKGKLGVPGL 803 Query: 642 GGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPG 683 G G + G+ G G G G+ GVA +PG Sbjct: 804 PGYPG-------RQGPKGSTGFPGFPGANGEKGARGVAGKPG 838 Score = 92.0 bits (227), Expect = 2e-18 Identities = 160/519 (30%), Positives = 179/519 (34%), Gaps = 119/519 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA----------GL 75 PG G P G PG V PG A G +G G+P P G AG G Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGP 1061 Query: 76 GAGLGAFPAVTFPGALVPGGVAD--------AAAAYKAAKAGAGLGGVPGVGGLGVSAGA 127 G V PG P G K +K G G PG GL GA Sbjct: 1062 AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121 Query: 128 VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAF 186 PG G+ G G++ GAR FPG P P G P PG G Sbjct: 1122 ----PGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG----PPGPIGLQGLPGPPGEKGEN 1173 Query: 187 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPT 246 + +GP G P P P G P A G G P + G + G G G G AG G P Sbjct: 1174 GDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPGPPG 1228 Query: 247 GTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV-------------- 273 GVG P AA AK K G G Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1288 Query: 274 LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGAAAG 321 GVGG G PG PG PG G AG P AA A K AK A A Sbjct: 1289 QDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAE 1347 Query: 322 LVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA-GIP 360 PG G GP G G PG G+PG G+PGA G P +PG G P Sbjct: 1348 GPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDP 1407 Query: 361 GA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFPGF- 407 G+ + G++ P E K PG G GGIP +G G PG Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLP 1467 Query: 408 -------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 439 G G G G G+ G PG G PG I P Sbjct: 1468 GPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506 Score = 62.4 bits (150), Expect = 1e-09 Identities = 95/329 (28%), Positives = 113/329 (34%), Gaps = 32/329 (9%) Query: 387 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGV------- 435 PG+ V G P AG G PG G G PG G PG G+PG G+PG Sbjct: 397 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 456 Query: 436 -----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 490 G + +A +A ++ +A + PG G+ PG PG Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIA--LRGPPG---PMGLTGRPGPVGGPGSSG 511 Query: 491 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 549 A G PG GP GV K + R A G G+PG G G G+ Sbjct: 512 AKGESGDPGPQGPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGFDGLPGL 569 Query: 550 PGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 604 PG G G PG + +PG G G LG G PG G Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629 Query: 605 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGAAGLG 664 A G G G G G G+PG G G PP K G AGL Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKPGLAGLP 687 Query: 665 GVLGGAGQFPLGGVAARPGFGLSPIFPGG 693 G G G G + G L P P G Sbjct: 688 GADGPPGHPGKEGQSGEKG-ALGPPGPQG 715 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.144 0.445 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,347,150 Number of Sequences: 37866 Number of extensions: 3051541 Number of successful extensions: 60622 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 481 Number of HSP's successfully gapped in prelim test: 934 Number of HSP's that attempted gapping in prelim test: 14239 Number of HSP's gapped (non-prelim): 13474 length of query: 705 length of database: 18,247,518 effective HSP length: 109 effective length of query: 596 effective length of database: 14,120,124 effective search space: 8415593904 effective search space used: 8415593904 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.