BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|126352322 elastin isoform c precursor [Homo sapiens] (692 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|126352322 elastin isoform c precursor [Homo sapiens] 1386 0.0 gi|126352446 elastin isoform d precursor [Homo sapiens] 1375 0.0 gi|126352608 elastin isoform e precursor [Homo sapiens] 1359 0.0 gi|126352440 elastin isoform a precursor [Homo sapiens] 1347 0.0 gi|126352700 elastin isoform b precursor [Homo sapiens] 1342 0.0 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 184 2e-46 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 175 1e-43 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 173 5e-43 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 167 2e-41 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 167 2e-41 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 167 2e-41 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 167 2e-41 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 165 1e-40 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 165 1e-40 gi|48762934 alpha 2 type I collagen [Homo sapiens] 162 1e-39 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 155 2e-37 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 153 6e-37 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 153 6e-37 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 149 8e-36 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 149 1e-35 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 149 1e-35 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 147 2e-35 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 146 7e-35 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 145 9e-35 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 144 2e-34 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 144 4e-34 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 140 3e-33 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 140 5e-33 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 138 2e-32 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 138 2e-32 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 1386 bits (3588), Expect = 0.0 Identities = 692/692 (100%), Positives = 692/692 (100%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 Query: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG Sbjct: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI Sbjct: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA Sbjct: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 Query: 661 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 >gi|126352446 elastin isoform d precursor [Homo sapiens] Length = 711 Score = 1375 bits (3558), Expect = 0.0 Identities = 692/711 (97%), Positives = 692/711 (97%), Gaps = 19/711 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 461 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480 Query: 462 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 521 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 481 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 540 Query: 522 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 581 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 541 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 600 Query: 582 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 641 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 601 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 660 Query: 642 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 661 GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACGRKRK 711 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 1359 bits (3517), Expect = 0.0 Identities = 687/710 (96%), Positives = 687/710 (96%), Gaps = 23/710 (3%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG Sbjct: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 475 Query: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG Sbjct: 476 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 535 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI Sbjct: 536 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 595 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA Sbjct: 596 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 655 Query: 661 AKY------------------GVAARPGFGLSPIFPGGACLGKACGRKRK 692 AKY GVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 656 AKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACLGKACGRKRK 705 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 1347 bits (3487), Expect = 0.0 Identities = 687/729 (94%), Positives = 687/729 (94%), Gaps = 42/729 (5%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 121 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 175 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 176 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 235 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 236 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 295 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 296 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 355 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 356 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 415 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY-------------------GLVP 461 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY GLVP Sbjct: 416 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475 Query: 462 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 521 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA Sbjct: 476 GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVA 535 Query: 522 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 581 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY Sbjct: 536 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKY 595 Query: 582 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 641 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL Sbjct: 596 GAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 655 Query: 642 GVPGVGGLGGIPPAAAAKAAKY------------------GVAARPGFGLSPIFPGGACL 683 GVPGVGGLGGIPPAAAAKAAKY GVAARPGFGLSPIFPGGACL Sbjct: 656 GVPGVGGLGGIPPAAAAKAAKYGAAGLGGVLGGAGQFPLGGVAARPGFGLSPIFPGGACL 715 Query: 684 GKACGRKRK 692 GKACGRKRK Sbjct: 716 GKACGRKRK 724 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 1342 bits (3473), Expect = 0.0 Identities = 677/692 (97%), Positives = 677/692 (97%), Gaps = 15/692 (2%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGG 60 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP ALGPGG Sbjct: 1 MAGLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYP----------ALGPGG 50 Query: 61 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 120 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG Sbjct: 51 KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG 110 Query: 121 LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 180 LGVSA GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV Sbjct: 111 LGVSA-----GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGV 165 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV Sbjct: 166 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 225 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI Sbjct: 226 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 285 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP Sbjct: 286 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 345 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 420 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP Sbjct: 346 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIP 405 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG Sbjct: 406 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 465 Query: 481 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG Sbjct: 466 VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 525 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI Sbjct: 526 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 585 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA Sbjct: 586 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 645 Query: 661 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 692 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK Sbjct: 646 AKYGVAARPGFGLSPIFPGGACLGKACGRKRK 677 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 184 bits (468), Expect = 2e-46 Identities = 239/719 (33%), Positives = 260/719 (36%), Gaps = 112/719 (15%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALG---------- 52 G T AA PG P+ P G PGA+ G P G G Sbjct: 326 GATGAAGPPGPT-------GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378 Query: 53 GGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGL 112 GA GP G P G GA G+ P FPGA P G G Sbjct: 379 AGAAGPAGNPGADGQPGAKGANGAPGIAGAPG--FPGARGPSGPQ-------------GP 423 Query: 113 GGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARF-PGVGVL 171 GG PG G S P PG+ GA +PG V G PG GAR PG L Sbjct: 424 GGPPGPKGN--SGEPGAPGSK-GDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480 Query: 172 PGVPTGAGVKPKAPGVGGAFAGIPGV-------GPFGGPQPGVPLGYPIKAPKLPGGYGL 224 PG P G PG G F G GV G G P P P G P +A + PG GL Sbjct: 481 PGPPGERG----GPGSRG-FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGR-PGEAGL 534 Query: 225 PYTTGKL--PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPG 281 P G P GP G G G AG G GP A A GAAG Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594 Query: 282 VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVV 339 G GVPG PGA+ G G A A + + G A G PGF PG Sbjct: 595 AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA-----GSPGFQGLPGPA 649 Query: 340 GVPG-AGVPGV-GVPG-AGIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGAR 391 G PG AG PG GVPG G P GA G PG V G P A GA+ Sbjct: 650 GPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK 709 Query: 392 PGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAA 451 G G P G+ G PG G+ G G AG+PG G G G G SP Sbjct: 710 GDAGAPGAP----GSQGAPGLQ-GMPGERGAAGLPGPKGDRGDAGPKGADGSP------- 757 Query: 452 AKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGV 510 K GL +G PG APG G G A G APG PG GP G Sbjct: 758 GKDGVRGLTGPIG-PPGPAGAPGDKGESGPSGPAGPTGARG---APGDRGEPGPPGPAGF 813 Query: 511 AAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVP 570 A + + AK + A G G PG AG PG G PG Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKG--------DAGPPGPAGPAGPPGPIGNVGAPG----- 860 Query: 571 GALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGA 630 AK A+ A PG G GA G VG PG AGP A G G Sbjct: 861 -----AKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915 Query: 631 AGL-GGLG-------VGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 679 AG G +G G G PG G G P P A + GV PG FPG Sbjct: 916 AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG 974 Score = 166 bits (421), Expect = 5e-41 Identities = 219/658 (33%), Positives = 248/658 (37%), Gaps = 67/658 (10%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAG-----AGLGA 77 P P G PG G+PG PG P G P P P GL G G Sbjct: 122 PRGPAGPPGR--DGIPGQPGLPG------------PPGPPGPPGPPGLGGNFAPQLSYGY 167 Query: 78 GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 + ++ PG + P G A G G PG G ++ P P P Sbjct: 168 DEKSTGGISVPGPMGPSGPRGLPGP-PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226 Query: 138 GAGVKPGKVPGVGLPGVY-PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG 196 G G+ G PG P G PG LPG+ G G+ GA Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFS----GLDGAKGDAGP 282 Query: 197 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGT 253 GP G +PG P AP G GLP G+ P GP G GA G AG P T Sbjct: 283 AGPKG--EPGSP--GENGAPGQMGPRGLPGERGR-PGAPGPAGARGNDGATGAAGPPGPT 337 Query: 254 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 313 GP AK AG G G GV G PG PG G AG PA A Sbjct: 338 --GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAG---PAGNPGAD 391 Query: 314 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----AGIPVVPGA-GIPGA- 367 A A G + G PGF PG G G PG G PG +G P PG+ G GA Sbjct: 392 GQPGAKGANGAPG-IAGAPGF-PGARGPSGPQGPG-GPPGPKGNSGEPGAPGSKGDTGAK 448 Query: 368 AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPG 427 PG V + A + K GAR G G+P G G G G G G PG GV G Sbjct: 449 GEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLP----GPPGERG-GPGSRGFPGADGVAG 503 Query: 428 VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV 487 G G G PG P+ A + + GL PG G +PG G G Sbjct: 504 PKGPAGERGSPGPA-GPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGPDGKTGPPGPAGQ 561 Query: 488 GVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGV 545 PG PG G A +G G AA K + +G AG G G Sbjct: 562 DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP 621 Query: 546 PGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYG-AAVPGVLGG---LGALGGVGI 600 PG AG G AG PGF +PG A +A K G VPG LG GA G G Sbjct: 622 PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681 Query: 601 PG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL-GGLGVGGL-GVPGVGGLGGIP 653 PG GV G GPA A A G GA G G G GL G+PG G G+P Sbjct: 682 PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLP 739 Score = 156 bits (395), Expect = 5e-38 Identities = 229/746 (30%), Positives = 263/746 (35%), Gaps = 127/746 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA--GLGALGG-------GALGPGGKPLK------PVP 67 P PGG PG P G G PG+ GA G G GP G+ K P P Sbjct: 420 PQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477 Query: 68 GGLAGAGL---GAGLGAFPAVTFPGALVPGGVADAAAAYKAA--KAGAGLGGVPGVGGL- 121 GL G G G FP G P G A + A K G G PG GL Sbjct: 478 TGLPGPPGERGGPGSRGFPGAD--GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-------FPGVGVLPGV 174 G PG+ P G PG G PG PG PGAR FPG G Sbjct: 536 GAKGLTGSPGSPGPDGKTG-PPGPAGQDGRPGP-PGP--PGARGQAGVMGFPGPKGAAGE 591 Query: 175 PTGAGVK--PKAPGVGGAFAGIPGVGPFGGPQPGVPLGY-----PIKAPK---LPGGYGL 224 P AG + P PG G G G P P P G P +P LPG G Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651 Query: 225 PYTTGK-----LPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFG 272 P GK +P G G +GA G+ G+P GV GP+ A A AK Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711 Query: 273 AGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL 327 AGA G G G+ G+PG +PG G G P A + K G + Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG--KDGVRGLTGPI 769 Query: 328 VPGGPGFGPGVVGVPGA----------GVPG----VGVPG-AGIPVVPGA-------GIP 365 P GP PG G G G PG G PG AG PGA G P Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829 Query: 366 G-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 418 G A PG P GA+ G G P GA GFPG G G Sbjct: 830 GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP----GATGFPG-AAGRVG 884 Query: 419 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVA 478 PG +G G G PG G G G P + A + + G PG G +PG A Sbjct: 885 PPGPSGNAGPPGPPGPAGKEG-GKGPRGETGPAGRPGEVG-PPGPPGPAGEKGSPG---A 939 Query: 479 PGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP 537 G APG G+ GV PG G G + + + A+ G P Sbjct: 940 DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGP 999 Query: 538 GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGG 597 +G PGL AG PG G PG PG + AK G G GA G Sbjct: 1000 -----MGPPGL---AGPPGESGREGAPGAEGSPGR-DGSPGAKGDRGETGPAGPPGAPGA 1050 Query: 598 VGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----------GVGGLGVPGV 646 G PG V AG + A A G VGA G G G G+ G Sbjct: 1051 PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110 Query: 647 GGLGGI--PPAAAAKAAKYGVAARPG 670 G G+ PP + G + G Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGASG 1136 Score = 155 bits (393), Expect = 9e-38 Identities = 217/693 (31%), Positives = 248/693 (35%), Gaps = 100/693 (14%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--------GALGPGGKPLKPVPGGLAGA 73 P+ P G PG G PG PGA GL G G GP G+ +P P G GA Sbjct: 516 PAGPKGSPGE--AGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573 Query: 74 GLGAGLGAFP----AVTFPGAL----VPGGVADAAAAYKAAKAGAGLGGVPGVGG----- 120 AG+ FP A PG VPG A K +AGA G PG G Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ--GPPGPAGPAGER 631 Query: 121 --LGVSAAPSVPGAVVPQ--PGAGVKPGK--VPG-VGLPGVYPGGVLPGARFPGVGVLPG 173 G + +P G P PG KPG+ VPG +G PG P G FPG + G Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG--PSGARGERGFPGERGVQG 689 Query: 174 VPTGAGVKPK--APGVGGAF--AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTG 229 P AG + APG GA AG PG P PG+ P G GLP G Sbjct: 690 PPGPAGPRGANGAPGNDGAKGDAGAPGA-PGSQGAPGLQ-----GMPGERGAAGLPGPKG 743 Query: 230 KLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 288 GP G G+ GK G TG +GP A A +G AG G G Sbjct: 744 DRGDA-GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDR 802 Query: 289 GVPGAIPGIGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA 344 G PG PG G AG G P A A G P GP G VG PGA Sbjct: 803 GEPGP-PGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861 Query: 345 -------GVPGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYG--ARPG- 393 G PG G PGA V P A PG P + G RPG Sbjct: 862 KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921 Query: 394 VGVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 442 VG G P GA G PG G+ G GV G+PG G G G+PG Sbjct: 922 VGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQGIAGQRGVVGLPGQRGERGFPGLPGPSG 980 Query: 443 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV--- 499 P Q + A + PG PG+ PG G APG +PG +PG Sbjct: 981 EPGKQGPSGASGERGP--PGPMGPPGLAGPPGESGREG---APGAEGSPGRDGSPGAKGD 1035 Query: 500 -GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 558 G GP G A + V + G P VG Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGP--------------- 1080 Query: 559 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 618 VGA P P + + G G G G G PG GP+ A+ A Sbjct: 1081 VGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGP 1140 Query: 619 AAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 651 G G GL GL G +G PG G G Sbjct: 1141 RGPPGSAGAPGKDGLNGL-PGPIGPPGPRGRTG 1172 Score = 140 bits (354), Expect = 3e-33 Identities = 184/573 (32%), Positives = 203/573 (35%), Gaps = 57/573 (9%) Query: 111 GLGGVPGVGGL-------GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGA 163 G G+PG GL G P + G PQ G G+ +PG P G Sbjct: 130 GRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG--PMGPSGPR 187 Query: 164 RFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYG 223 PG PG P G P PG GA + GP G P G K P PG G Sbjct: 188 GLPGPPGAPG-PQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK-PGRPGERG 245 Query: 224 LPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVG 283 P GP G G G AG P G + + AK AG AG G Sbjct: 246 PP----------GPQGARGLPGTAGLP-----GMKGHRGFSGLDGAKGDAGPAGPKGEPG 290 Query: 284 GAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVP 342 G G PG + G G+ G G P A A A GAA P GP G G P Sbjct: 291 SPGENGAPGQM-GPRGLPGERGRPGAPGPAGARGNDGATGAAG---PPGPTGPAGPPGFP 346 Query: 343 GAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGI 399 GA VG G P P V G P A AA A GA +PG G G Sbjct: 347 GA----VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA 402 Query: 400 PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 P GA GFPG G G G G PG G G G PG + A + G+ Sbjct: 403 PGI-AGAPGFPG-ARGPSGPQGPGGPPGPKGNSGEPGAPG----SKGDTGAKGEPGPVGV 456 Query: 460 --VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKS 516 PG G A G G+ PG PG PG GVA GP G A S Sbjct: 457 QGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVA---GPKGPAGERGS 513 Query: 517 AAKVAAKAQLRAAAGLG-AGIP---GLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA 572 K A G AG+P GL G PG G PG G PG PGA Sbjct: 514 PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573 Query: 573 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 632 A + G G G G G+PG GPA A A G G G Sbjct: 574 RGQAGVMGF-PGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632 Query: 633 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGV 665 G G G G+ G G PP A K + GV Sbjct: 633 EQG-PAGSPGFQGLPGPAG-PPGEAGKPGEQGV 663 Score = 111 bits (277), Expect = 3e-24 Identities = 159/499 (31%), Positives = 178/499 (35%), Gaps = 111/499 (22%) Query: 236 GPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKF----------GAGAAGV 278 GP G AG G+ G P G+ GP A + G G Sbjct: 121 GPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP 180 Query: 279 LPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYG--------AAAGLVP 329 + G G+PG PGA PG G G G P A+ G AG P Sbjct: 181 MGPSGPRGLPGPPGA-PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG-KP 238 Query: 330 GGPG-FGP----GVVGVPG-AGVPGV-------GVPGA----------GIPVVPGA-GIP 365 G PG GP G G+PG AG+PG+ G+ GA G P PG G P Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298 Query: 366 G----AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPG 421 G +PG A A GA G G PT G GFPG VG G G Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPG-PTGPAGPPGFPG-AVGAKGEAG 356 Query: 422 VAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 481 G G G GV G PG P A AA A PG PG A G APG+ Sbjct: 357 PQGPRGSEGPQGVRGEPG----PPGPAGAAGPAGN----PGADGQPG---AKGANGAPGI 405 Query: 482 GLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 APG A G G G PG G G A S AK G PG Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAK-----------GEPG-- 452 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG---- 596 VGV G AG G G PG +PG PG GG G+ G Sbjct: 453 -PVGVQGPPGPAGEEGKRGARGEPGPTGLPGP-------------PGERGGPGSRGFPGA 498 Query: 597 -GVGIPGGVVG----AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 651 GV P G G GPA + A + + GL GA GL G G PG G G Sbjct: 499 DGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL----TGSPGSPGPDGKTG 554 Query: 652 IPPAAAAKAAKYGVAARPG 670 PP A + + G PG Sbjct: 555 -PPGPAGQDGRPGPPGPPG 572 Score = 109 bits (273), Expect = 7e-24 Identities = 158/456 (34%), Positives = 172/456 (37%), Gaps = 68/456 (14%) Query: 26 PGGVPGAIPGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P G PG P G PG G P G G GA G G+P P P G AG G Sbjct: 768 PIGPPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ--- 822 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPG-VGGLGVSAAPSVPGAVVPQPGAG 140 PGA G DA A A G AG G PG +G +G A G+ P PGA Sbjct: 823 -----PGA--KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP-PGAT 874 Query: 141 VKPGKVPGVGLPGVYPGGVLPG-------------------ARFPGVGVLPGVPTGAGVK 181 PG VG PG PG A PG PG P AG K Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEK 934 Query: 182 PKAPGVGGAFAGIPGV-GPFG-GPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYG 234 +PG G AG PG GP G Q GV +G P + P LPG G P G P G Sbjct: 935 G-SPGADGP-AGAPGTPGPQGIAGQRGV-VGLPGQRGERGFPGLPGPSGEPGKQG--PSG 989 Query: 235 Y----GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 290 GP G G G AG P +G + A A GA G G AG PG Sbjct: 990 ASGERGPPGPMGPPGLAGPPGESG--REGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047 Query: 291 PGA--IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGV 346 PGA PG G AG G A A GA P GP G G G G+ Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107 Query: 347 PGV-GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG 405 G G G P P G PG P S A + +A GA G+ G+P G Sbjct: 1108 KGHRGFSGLQGPPGP-PGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLP----G 1160 Query: 406 AGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVG 441 G PG G G G G PG G PG G P G Sbjct: 1161 PIGPPG-PRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 84.0 bits (206), Expect = 4e-16 Identities = 122/376 (32%), Positives = 139/376 (36%), Gaps = 44/376 (11%) Query: 23 PSRPGGVPGAI-----PG--------GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGG 69 P+ P G PG I PG G PG +PGA G +G GP G P P G Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA-GRVGPP--GPSGNAGPPGPPG 899 Query: 70 LAGAGLGAG-LGAFPAVTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGL-GVSA 125 AG G G G PG + P G A A AG G PG G+ G Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVY-PGGVLPGARFPGVGVLPGV--PTGAGVKP 182 +PG Q G PG G PG P G PG PG+ P G + Sbjct: 960 VVGLPG----QRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015 Query: 183 KAPGVGGAFA--GIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGG 239 APG G+ G PG G G P P G P AP PG G +G G G Sbjct: 1016 GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP-GAPGAPGPVGPAGKSGDR----GETG 1070 Query: 240 VAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIG 298 AG AG G G GPQ + + G G G G PG PG+ PG Sbjct: 1071 PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS-PGEQ 1129 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG----A 354 G +G PA +A A GL GP PG G G P VG PG Sbjct: 1130 GPSGASGPAGPRGPPGSAGAPGKDGLNGL--PGPIGPPGPRGRTGDAGP-VGPPGPPGPP 1186 Query: 355 GIPVVPGAGIPGAAVP 370 G P P AG + +P Sbjct: 1187 GPPGPPSAGFDFSFLP 1202 Score = 73.9 bits (180), Expect = 5e-13 Identities = 91/292 (31%), Positives = 106/292 (36%), Gaps = 29/292 (9%) Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL---------VPGVGV 465 G G PG G+PG G+PG G PG P A YG VPG Sbjct: 124 GPAGPPGRDGIPGQPGLPGPPGPPGPP-GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMG 182 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKA 524 G PG APG G PG A G +G GP G A K Sbjct: 183 PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242 Query: 525 QL-----RAAAGL--GAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGALA 574 + + A GL AG+PG+ G GL AG G G PG PG + Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302 Query: 575 ----AAKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVG 629 + + GA P G G GA G G PG AGP A A +A G G Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362 Query: 630 AAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 679 + G G+ G G PG G G P A + G PG +P FPG Sbjct: 363 SEGPQGVR-GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 175 bits (444), Expect = 1e-43 Identities = 222/700 (31%), Positives = 257/700 (36%), Gaps = 107/700 (15%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG P G PG +PG+ G GP G+P + P G G Sbjct: 175 PAGPPG--PPGPPGTSGHPGSPGSP---GYQGPPGEPGQAGPSGPPGP------------ 217 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGVK 142 PGA+ P G A D + GL G PG+ G G+ P + G G + Sbjct: 218 --PGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKG----HRGFDGR 271 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFG 201 G+ G PG+ LPG PG G P G +P PG GA G G Sbjct: 272 NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG-RPGLPGAAGARGNDGARGSDG 330 Query: 202 GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAA 260 P P P PG G P + G G G AG+ G G P G GPQ Sbjct: 331 QPGPPGP----------PGTAGFPGSPG----AKGEVGPAGSPGSNGAPGQRGEPGPQGH 376 Query: 261 AAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAK 320 A A G+ G +G AG+PG PG + G G A A + K Sbjct: 377 AGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK 436 Query: 321 YGAAAGLVPGGPGFGPGVVGVPGA----------GVPGV-GVPGA----GIPVVPGA--- 362 GA P G G+ GVPGA G PG G+PGA G P G Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496 Query: 363 -GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPG--FG 413 GIPG P G P AA + + G G G+ G+P G G+ G PG Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGV 471 G G PG G G G PGV G PG P+ A K + G PG PG Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPG----PKGNDGAPGKNGERGGPGGPGPQGPPGKNG 612 Query: 472 APGVGVAPGV--------GLAP----GVGVAPGVGVAPGVGVAPG-IGPGGVAAA--AKS 516 G PG P G+ PG G PG PG GP G A A A Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672 Query: 517 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG---AGVPGLGVGAGVPGFGAVPGAL 573 A R GL AG PGL G G PG G AG PG AG PG +PG Sbjct: 673 GKGDAGAPGERGPPGL-AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG-- 729 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGV---GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGA 630 + G PG G G GG G+PG GP A + G GA Sbjct: 730 -----ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784 Query: 631 AGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 670 GL G+ G G PG G G PP A G PG Sbjct: 785 PGLPGI-AGPRGSPGERGETG-PPGPAGFPGAPGQNGEPG 822 Score = 166 bits (421), Expect = 5e-41 Identities = 217/671 (32%), Positives = 257/671 (38%), Gaps = 121/671 (18%) Query: 26 PGGVPGAI-PGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLGA 81 P G PG PGG G PG GL L G G G GKP +P P G AGA Sbjct: 616 PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA-------- 667 Query: 82 FPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV----------GGLGVSAAPSVPG 131 PGA PGG DA A + GL G PG+ GG G + P PG Sbjct: 668 ------PGA--PGGKGDAGAP--GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPG 717 Query: 132 AVVPQPGAGVKPGKVPGVGLPGVY-----PGGV----LPGARFPGVGVLPGVPTGAGVKP 182 A PG PG+ G+G PG PGG +PG P P P G +P Sbjct: 718 AA-GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQP 776 Query: 183 KAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYGYGPGG 239 G GGA G+PG+ GP G P G P A P PG G P G+ G G Sbjct: 777 GDKGEGGA-PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG-APGEKG 834 Query: 240 VAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIG 298 G G AG P G+G GP + + G GAAG G G+PG PG+ Sbjct: 835 EGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF---PGARGLPGPPGS----- 886 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPGA-G 355 G P + + K G A G PG PGV G G AG PG G PGA G Sbjct: 887 ----NGNPGPPGPSGSPGKDGPPGPAGN--TGAPG-SPGVSGPKGDAGQPGEKGSPGAQG 939 Query: 356 IPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 P PG GI G GAR G G+P G G P Sbjct: 940 PPGAPGPLGIAGIT--------------------GARGLAGPPGMP----GPRGSP---- 971 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G+ G +G PG G+ G G PG P+ A A + PG PG PG Sbjct: 972 GPQGVKGESGKPGANGLSGERGPPG----PQGLPGLAGTAGE----PGRDGNPGSDGLPG 1023 Query: 475 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG 533 +PG G +PG APG PG +GP G + + + A A AG Sbjct: 1024 RDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAG-KSGDRGESGPAGPAGAPGPAG-S 1081 Query: 534 AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA-AVPGVLGGL 592 G PG G G G G+ G PG PG + A + GA PG G Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG--SPGPAGQQGAIGSPGPAGPR 1139 Query: 593 GALGGVGIPG--------GVVG----AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 640 G +G G PG G +G G + + Q G G G G GG Sbjct: 1140 GPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGG 1199 Query: 641 LGVPGVGGLGG 651 +G + G+GG Sbjct: 1200 VGAAAIAGIGG 1210 Score = 163 bits (412), Expect = 6e-40 Identities = 230/712 (32%), Positives = 255/712 (35%), Gaps = 131/712 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 PS P G PGAI P AG G PG + L P P G+ G AG+ F Sbjct: 211 PSGPPGPPGAIGPSGP-------AGKDGESGRPGRPGERGL-PGPPGIKGP---AGIPGF 259 Query: 83 PAVT----FPGALVPGGVADAAAAYKAAKAGAGLGGVPGV----GGLGVSAAPSVPGAVV 134 P + F G G A K G G PG G G P +PGA Sbjct: 260 PGMKGHRGFDGRNGEKG-ETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAG 318 Query: 135 P-----------QPGAGVKPGKVPGVGLPG----VYPGGVLPGARFPGVGVLPGVPTGAG 179 QPG PG G PG V P G PG PG AG Sbjct: 319 ARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378 Query: 180 VK--PKAPGVGGA--------FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTT 228 + P PG+ G+ AGIPG G G P P G AP L GG G P Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG-ANGAPGLRGGAGEPGKN 437 Query: 229 GKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 288 G G G G G+AG P G A K + GA G+ G G P Sbjct: 438 G----AKGEPGPRGERGEAGIP-----GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAP 488 Query: 289 GV-----PGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVG 340 G P IPG G AG G P A AA + + G VPGGPG PG G Sbjct: 489 GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDG-----VPGGPGMRGMPGSPG 543 Query: 341 VPGA-GVPGVGVPG----AGIPVVPGAGIPGA--AVPGVVSPEAAAKAAAKAAKYGARPG 393 PG+ G P G PG +G P PG P V G P+ A K + G G Sbjct: 544 GPGSDGKP--GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601 Query: 394 VGVGGIPTYG-----------VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGI 442 G G P G GG G G G G+ G+PG GG PG G PG Sbjct: 602 PGPQGPPGKNGETGPQGPPGPTGPGGDKG-DTGPPGPQGLQGLPGTGGPPGENGKPGEP- 659 Query: 443 SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV-GVAPGVGVAPGVGV 501 P+ A A PG G APG PG+ APG+ G A G G G Sbjct: 660 GPKGDAGA----------PGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGA 709 Query: 502 APGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA 561 A GP G A GL G+PG G+G PG G PG G GA Sbjct: 710 AGPPGPPGAA----------------GTPGL-QGMPGERGGLGSPGPKGDKGEPG-GPGA 751 Query: 562 -GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 620 GVPG G PG G G G G PG AGP + Sbjct: 752 DGVPGKDGPRGPTGP-------IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG 804 Query: 621 KAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 670 G GA G G G G G PG G GG PP A G A PG Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG-PPGVAGPPGGSGPAGPPG 855 Score = 133 bits (335), Expect = 5e-31 Identities = 183/559 (32%), Positives = 204/559 (36%), Gaps = 82/559 (14%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPG-AGLGALGGGA--LGPGGKPLKPVPGGLAGAGL 75 P G PGA G G PG PG AG L GGA GP G P G GA Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG 720 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP 135 GL P G PG D K G G GVPG G P P Sbjct: 721 TPGLQGMPGER-GGLGSPGPKGD-----KGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG 774 Query: 136 QP---GAGVKPGKVPGVGLPGVYPG-----GVLPGARFPGVGVLPGVPTGAGVKPKAPGV 187 QP G G PG +PG+ P PG G A FPG G P G G + APG Sbjct: 775 QPGDKGEGGAPG-LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER-GAPGE 832 Query: 188 GGAFAGIPGV-GPFGGPQPGVPLG-YPIK----APKLPGGYGLPYTTGKLPYGYGPGGVA 241 G G PGV GP GG P P G +K +P PG G P G LP G G Sbjct: 833 KGE-GGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG-LPGPPGSNGNP 890 Query: 242 GAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G +G P G G A + + K AG G G G PG PG + GI Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL-GI 949 Query: 298 GGIAGV-------------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA 344 GI G G+P + K G + P GP PG+ G A Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT--A 1007 Query: 345 GVPG-VGVPGA-GIPVVPGA----------GIPGA-AVPGVVSPEAAAKAAAKAAKYGAR 391 G PG G PG+ G+P G+ G PGA PG P A K+ G Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067 Query: 392 PGVGVGGIPTYGVGAGGFPG-----FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEA 446 G G P G+ G PG G G G AG+ G G PG G PG P Sbjct: 1068 GPAGPAGAPG-PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPG-SPGPAG 1125 Query: 447 QAAAAAKAAKYGLVPGVGVA-----------PGVGVAPGVGVAPGVGLAPGVGVAPGVGV 495 Q A G VG + PG PG G + G PG Sbjct: 1126 QQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185 Query: 496 APGVGVAPGIGPGGVAAAA 514 PG APG GGV AAA Sbjct: 1186 PPGPPGAPGPCCGGVGAAA 1204 Score = 126 bits (317), Expect = 6e-29 Identities = 171/533 (32%), Positives = 199/533 (37%), Gaps = 91/533 (17%) Query: 175 PTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 233 P G P PG+ G G PG+ G G P P G P P Y Y + + Sbjct: 104 PQGPKGDPGPPGIPGR-NGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162 Query: 234 GYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 293 G GG+AG G AG P GP G +G G G G PG Sbjct: 163 GVAVGGLAGYPGPAGPP-----GPPGP------------PGTSGHPGSPGSPGYQGPPGE 205 Query: 294 IPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPG-AGVPGV 349 PG G +G G P A + A K + G PG PG PG G+ G AG+PG Sbjct: 206 -PGQAGPSGPPGPPGAIGPSGPAGKDGESGR-----PGRPGERGLPGPPGIKGPAGIPGF 259 Query: 350 -GVPG-------------AGIPVVPGA-GIPGA-AVPGVVSPEAA---------AKAAAK 384 G+ G G P + G G+PG PG + P A AA Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319 Query: 385 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 GAR G G P G GFPG G G G AG PG G PG G PG P Sbjct: 320 RGNDGARGSDGQPG-PPGPPGTAGFPG-SPGAKGEVGPAGSPGSNGAPGQRGEPG----P 373 Query: 445 EAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG 504 + A A PG+ +PG G PG APG+ A G G APG Sbjct: 374 QGHAGAQGPPGP----PGINGSPGGKGEMGPAGIPG---APGLMGARGPPGPAGANGAPG 426 Query: 505 IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVP 564 + GG K+ AK + R G AGIP GVPG G G G P Sbjct: 427 L-RGGAGEPGKNGAK--GEPGPRGERG-EAGIP------GVPG---AKGEDGKDGSPGEP 473 Query: 565 GFGAVPGALAAAKAAKY-GAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 622 G +PGA A + G A P G+ G G G G PG AGP AA Sbjct: 474 GANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPG---PAGPRGAAGEPGRDGVP 530 Query: 623 AQFGLVGAAGLGGLGVGGLGVPGVGGLGGI-----PPAAAAKAAKYGVAARPG 670 G+ G G G G G G PG G G PP + + GV PG Sbjct: 531 GGPGMRGMPGSPG-GPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582 Score = 125 bits (314), Expect = 1e-28 Identities = 161/523 (30%), Positives = 190/523 (36%), Gaps = 98/523 (18%) Query: 203 PQPGVPLG-------YPIKAPKLP-------GGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 P P +P G P AP P G G P G +P G G+ G G G Sbjct: 75 PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG-IPGRNGDPGIPGQPGSPG 133 Query: 249 YPTGTGV------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 P G+ GPQ + K G G+ G AG PG PG PG G G Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP-PGTSGHPG 192 Query: 303 -VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG-VGVPG----AG 355 G+P +A P GP PG +G G AG G G PG G Sbjct: 193 SPGSPGYQGPPGEPGQAG---------PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243 Query: 356 IPVVPG----AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG-----VGA 406 +P PG AGIPG PG+ + + GA G G+P +G Sbjct: 244 LPGPPGIKGPAGIPG--FPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 466 G PG G G+PG AG G G G G PG P + AK G V G + Sbjct: 302 RGAPG-ERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAK-GEVGPAG-S 358 Query: 467 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVAAAAKSAAKVAA 522 PG APG PG G PG PG+ +PG +GP G+ Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPG---PPGINGSPGGKGEMGPAGI------------ 403 Query: 523 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 582 G PGL G PG G PGL GAG PG G + + Sbjct: 404 -----------PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE-PGPRGERGE 451 Query: 583 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-----G 637 A +PGV G G G G P G GA AA + A G G AG G+ Sbjct: 452 AGIPGVPGAKGEDGKDGSP-GEPGANGLPGAAGERGAP-----GFRGPAGPNGIPGEKGP 505 Query: 638 VGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 680 G G PG G P AA + + GV PG P PGG Sbjct: 506 AGERGAPGPAG----PRGAAGEPGRDGVPGGPGMRGMPGSPGG 544 Score = 104 bits (259), Expect = 3e-22 Identities = 153/474 (32%), Positives = 167/474 (35%), Gaps = 70/474 (14%) Query: 23 PSRPGGVPGAI-PGGVPG--GVFYPGAGLGALGG-GALGPGGKPLKP----VPGGLA--G 72 P P G PG GG PG G+ P G G G GP G P P PGG G Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAA-------AYKAAKAGAGLGGVPGVGGL---- 121 A G G P V P PGG A + + G G G PG GL Sbjct: 829 APGEKGEGGPPGVAGP----PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP 884 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPG--GVLPGARFPGVGVLPGV--PTG 177 G + P PG PG PG G PG PG G A PG PG P G Sbjct: 885 GSNGNPGPPGPS-GSPGKDGPPGPAGNTGAPGS-PGVSGPKGDAGQPGEKGSPGAQGPPG 942 Query: 178 AGVKPKAPGVGGA--FAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG 234 A G+ GA AG PG+ GP G P P G K PG GL G Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK----PGANGLSGERGPP--- 995 Query: 235 YGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGA 293 GP G+ G AG AG P G G K G G G G PG PG Sbjct: 996 -GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGP 1054 Query: 294 IPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GV 351 + G G A A A A GA P GP G G GA G+ G G Sbjct: 1055 VGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG---PQGPRGDKGETGERGAAGIKGHRGF 1111 Query: 352 PG-AGIPVVPG-AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP-------- 400 PG G P PG AG GA PG P + K G G G P Sbjct: 1112 PGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGE 1171 Query: 401 TYGVGAGGFPGF----------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G+ G PG G GG+ G A + G+GG G P G P Sbjct: 1172 RGSEGSPGHPGQPGPPGPPGAPGPCCGGV-GAAAIAGIGGEKAGGFAPYYGDEP 1224 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 173 bits (438), Expect = 5e-43 Identities = 220/742 (29%), Positives = 279/742 (37%), Gaps = 134/742 (18%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--GVPGAI----PGGVPGGVFYPGA---------- 46 G+T A PG HP PG G PG++ G PGGV +PG+ Sbjct: 553 GMTGRAGSPG------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPP 606 Query: 47 GLGALGG----------------GALGPGGKPLK--PVPGGLAGAGLGAGLGAFPAVT-- 86 G G G G GP G+P K P+PG GL G FP Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG-FPGPQGD 665 Query: 87 --FPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-------GGLGVSAAPSVPG--AVVP 135 FPG PG + G G G PG G +G P PG + Sbjct: 666 RGFPGT--PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG 723 Query: 136 QPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA--G 193 PG + G+ PGVGLPG+ LPG PG+ PG GV P PG GA G Sbjct: 724 NPGVQGQKGE-PGVGLPGLKG---LPG--LPGIPGTPGEKGSIGV-PGVPGEHGAIGPPG 776 Query: 194 IPGV----GPFGGP----QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 245 + G+ GP G P PGVP P A PGG G P +G P G+ G G Sbjct: 777 LQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSG-------PPGIKGEKG 829 Query: 246 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGGIAGVG 304 G+P GP+ A +G G LPG GA G+PG PG+ +G + G Sbjct: 830 FPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG-LPGQQGAPGIPGFPGSKGEMGVMGTPG 888 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI 364 P + A + G GP PG+ G G VG+PG Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG----DVGLPGK---------- 934 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAG 424 PG + + G + +G P G+ G P G G+PG G Sbjct: 935 -----PGSMDKVDMGSMKGQKGDQGEKGQIG----PIGEKGSRGDP----GTPGVPGKDG 981 Query: 425 VPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL-VPGVGVAPGVGVAPGVGVAPGVGL 483 G G PG G PG+ +P A K + G+ +PG GV PG +PG+ Sbjct: 982 QAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPG 1041 Query: 484 APGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPG 538 G G PG+G+ PG+ G G+A S + K + G+ G+ G Sbjct: 1042 DKGAKGEKGQAGPPGIGI-PGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKG 1100 Query: 539 LGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGV 598 VG PG G+PG G+PG +PG K A +PG G G G Sbjct: 1101 SPGSVGYPG---SPGLPGEKGDKGLPGLDGIPG-------VKGEAGLPGTPGPTGPAGQK 1150 Query: 599 GIPGGVVGAGPAAAAAAAKAAAKAAQF-GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAA 657 G PG P +A + F G GA G G G +G PG+ G GIP Sbjct: 1151 GEPGS--DGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG-SKGEVGFPGLAGSPGIP---- 1203 Query: 658 AKAAKYGVAARPGFGLSPIFPG 679 + G PG P PG Sbjct: 1204 GSKGEQGFMGPPGPQGQPGLPG 1225 Score = 172 bits (436), Expect = 9e-43 Identities = 223/744 (29%), Positives = 281/744 (37%), Gaps = 117/744 (15%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPG--GVPGA--IPG--------GVPGGVFYPGAGLGA 50 GL PG ++ L P PG G+PG+ PG G PG PG GA Sbjct: 630 GLPGPKGEPGKIVPL-----PGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEK-GA 683 Query: 51 LGGGALG----PGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAA 106 +G +G PG K + +PG + G G PG V G + Sbjct: 684 VGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPG--VQGQKGEPGVGLPGL 741 Query: 107 KAGAGLGGVPGV----GGLGVSAAPSVPGAVVP--------QPGAGVKPGKVPGVGLPGV 154 K GL G+PG G +GV P GA+ P +PG PG V G+PG+ Sbjct: 742 KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI 801 Query: 155 YPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG--AFAGIPGV---GPFG--GPQPGV 207 P PGAR P G P +G PG+ G F G PG+ GP G G Q Sbjct: 802 GP----PGARGPPGGQGPPGLSGP------PGIKGEKGFPGFPGLDMPGPKGDKGAQGLP 851 Query: 208 PLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKA 267 + P LPG G P G P G GV G G+ G P GP A + Sbjct: 852 GITGQSGLPGLPGQQGAPGIPG-FPGSKGEMGVMGTPGQPGSP-----GPVGAPGLPGEK 905 Query: 268 AAKFGAGAAGVL--PGV----GGAGVPGVPGAIPGI---------------GGIAGVGTP 306 G++G PG+ G G+PG PG++ + G I +G Sbjct: 906 GDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEK 965 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV--GVPGAGIPVVPGA- 362 + K G A GP PG+ G PGA G+PG V G G+P PG Sbjct: 966 GSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEK 1025 Query: 363 GIPGAAVPGVV-SPEAAAKAAAKAAKYGARP-GVGVGGI--PTYGVGAGGFPGFGVGVGG 418 G+PG +PG SP AK K A P G+G+ G+ G GFPG G G Sbjct: 1026 GVPG--IPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPG-SPGEKG 1082 Query: 419 IPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVA 478 G G+PG+ G PG+ G PG P + K K GL PG+ PGV G+ Sbjct: 1083 EKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDK-GL-PGLDGIPGVKGEAGLPGT 1140 Query: 479 PGVGLAPGVGVAPGVGVAPGVGVA---PGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAG 535 PG G PG PG PG+ G + +K ++ G Sbjct: 1141 PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEV--------G 1192 Query: 536 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGAL 595 PGL G+PG G G G G +PG+ G A G G G Sbjct: 1193 FPGLAGSPGIPG---SKGEQGFMGPPGPQGQPGLPGS--------PGHATEGPKGDRGPQ 1241 Query: 596 GGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPA 655 G G+PG GP G GA G+ G G G G+ G+GG P Sbjct: 1242 GQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPG-PKGDPGFQGMPGIGGSPGI 1300 Query: 656 AAAKAAKYGVAARPGFGLSPIFPG 679 +K G PGF PG Sbjct: 1301 TGSK-GDMGPPGVPGFQGPKGLPG 1323 Score = 169 bits (427), Expect = 1e-41 Identities = 230/734 (31%), Positives = 285/734 (38%), Gaps = 123/734 (16%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P RPG G+PG GV G PG GL PG K L +PG G +G Sbjct: 713 PGRPGFNGLPGN--PGVQGQKGEPGVGL---------PGLKGLPGLPGIPGTPGEKGSIG 761 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAG 140 GA+ P G+ G G PGV G+G A PG P PG Sbjct: 762 VPGVPGEHGAIGPPGL-QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGP-PGLS 819 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPG--- 196 PG G PG +PG +PG + G LPG+ TG P PG GA GIPG Sbjct: 820 GPPGIKGEKGFPG-FPGLDMPGPKGDKGAQGLPGI-TGQSGLPGLPGQQGA-PGIPGFPG 876 Query: 197 ----VGPFGGP-QPGVPLGYPIKAPKLPG---GYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 +G G P QPG P P+ AP LPG +G P ++G G G+ G G G Sbjct: 877 SKGEMGVMGTPGQPGSP--GPVGAPGLPGEKGDHGFPGSSGPR----GDPGLKGDKGDVG 930 Query: 249 YPTGTGVGPQAAAAAAAKAAAKFGA-GAAGVLPGVGGAGVPGVPGAIPGIGGIAGV---- 303 P G + + G G G + G G PG PG +PG G AG Sbjct: 931 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG-VPGKDGQAGQPGQP 989 Query: 304 ---GTPAAAAAAAAAAKAAKYGAAAGL-VPGGPGFGPGVVGVPGA-GVPGV-GVPGA--- 354 G P + A G+ G+ +PG PG GV G+PG G PG+ G GA Sbjct: 990 GPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG-EKGVPGIPGPQGSPGLPGDKGAKGE 1048 Query: 355 -GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 G PG GIPG + G + A + G + +G+ G+P G G PG Sbjct: 1049 KGQAGPPGIGIPG--LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPG-SPGLKGSPG-S 1104 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGV----GI----SPEAQAAAAAKAAKYGLVPGVGV 465 VG G PG+ G G G+PG+ G+PGV G+ P A + G +PG Sbjct: 1105 VGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG-IPGSAG 1163 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-------------GPGGVAA 512 G PG G PG A G + G PG+ +PGI GP G Sbjct: 1164 EKGEPGLPGRGF-PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPG 1222 Query: 513 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGL----GVGA--------GVPGLGVG 560 S + G+PGL +G PGL GV G PG+ Sbjct: 1223 LPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGP 1282 Query: 561 AGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLG--GLGALGGV-------GIPGGVVG 606 G PGF +PG + +K VPG G GL L G+ G+PG Sbjct: 1283 KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGL 1342 Query: 607 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL----GVPGVGGLGGIPPAAAAKAA 661 GP + GL G G GL G+ GL G GV GL GIP Sbjct: 1343 PGPPGPPGPYDII--KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIP-------- 1392 Query: 662 KYGVAARPGFGLSP 675 G PGF +P Sbjct: 1393 --GPPGIPGFDGAP 1404 Score = 149 bits (376), Expect = 8e-36 Identities = 218/707 (30%), Positives = 266/707 (37%), Gaps = 184/707 (26%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87 G PG P G+PG V PG G G G G P P GL+G G FP F Sbjct: 782 GEPG--PPGLPGSVGSPGVP----GIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG--F 833 Query: 88 PGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPG--------AVVPQPG 138 PG +PG D K A+ G+ G G+ GL G AP +PG V+ PG Sbjct: 834 PGLDMPGPKGD-----KGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG 888 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVP------------- 175 PG V GLPG PG+ P G LPG P Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948 Query: 176 ----------------TGAGVKPKAPGVGG--AFAGIPGV-GPFGGP----QPGVPLGYP 212 G+ P PGV G AG PG GP G P PG P G P Sbjct: 949 QKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP-GLP 1007 Query: 213 IKAPK-LPGGYGLPYTTGKL-------PYGY----GPGGVAGAAGKAGYPTGTGV----- 255 PK GG GLP T G+ P G G G G G+AG P G G+ Sbjct: 1008 --GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG-PPGIGIPGLRG 1064 Query: 256 --GPQAAAAAAAKAAAKFGAGAAGV--LPG----------VGGAGVPGVPG-----AIPG 296 G Q A K G+ G+ +PG VG G PG+PG +PG Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG 1124 Query: 297 IGGIAGV----GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG---- 348 + GI GV G P A + + G+ +PG G G G+PG G PG Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDG--IPGSAG-EKGEPGLPGRGFPGFPGA 1181 Query: 349 ---------VGVPG-AGIPVVPGA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGA 390 VG PG AG P +PG+ G PG PG+ A K + G Sbjct: 1182 KGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR-GP 1240 Query: 391 RPGVGVGGIPTYGVGAGGFPGF-GV----------GVGGIPGVAGVPGVGGVPGVGGVPG 439 + G+ G+P +G G PG GV G G+PG G PG G+PG+GG PG Sbjct: 1241 QGQPGLPGLPG-PMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG 1299 Query: 440 VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV 499 + +K + P PGV PG G+ G+ G PG Sbjct: 1300 I------------TGSKGDMGP-----PGV---PGFQGPKGLPGLQGIKGDQGDQGVPGA 1339 Query: 500 GVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLG 558 PG GP G K + GL G+PG GV GL G+PG Sbjct: 1340 KGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGL-QGLPGPKGQQGVTGL---VGIPG-- 1393 Query: 559 VGAGVPGFGAVPGALAAAKAAKYGAAVP-GVLGGLGALGGVGIPGGV 604 G+PGF PG + + G A P G G G G G+PG + Sbjct: 1394 -PPGIPGFDGAPG-----QKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1434 Score = 139 bits (349), Expect = 1e-32 Identities = 215/712 (30%), Positives = 257/712 (36%), Gaps = 108/712 (15%) Query: 22 HPSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLG 76 +P PG +PG IPG G PG PG G LGP G P P P GL G Sbjct: 101 YPGNPG-LPG-IPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGD 158 Query: 77 AG--LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G LG P + G + G+ G PG GL P P Sbjct: 159 PGEILGHVPGMLLKGE----------------RGFPGIPGTPGPPGLPGLQGPVGPPGFT 202 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP-------GV 187 PG PG G G+ G GV PGVP A V+ K G Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQ 262 Query: 188 GG--AFAGIPGVGPFGGPQPGVPLGYPIK--------APKLPGGYGLPYTTGKLPYGYGP 237 G F G+PGVG G P P G P K +P PG G P G+ GP Sbjct: 263 KGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR----QGP 318 Query: 238 GGVAGAAGKAGYP-TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPG 296 G G AG G P G GP + + G G G G PG+PG PG Sbjct: 319 QGEKGEAGPPGPPGIVIGTGP------LGEKGERGYPGTPGPRGEPGPKGFPGLPGQ-PG 371 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGA-GVPGV---- 349 G+ G A + G +PG G PG G PG G PG Sbjct: 372 PPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGI 431 Query: 350 -----GVPG-AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPG-------VG 395 G PG G P +PG PG G + + Y PG +G Sbjct: 432 VECQPGPPGDQGPPGIPGQ--PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIG 489 Query: 396 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG---VGISPEAQAAAAA 452 G P G G PG GV G+PG G PG+ G PG G PG + + Sbjct: 490 FPGQPG-AKGDRGLPGRD-GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG 547 Query: 453 KAAKYGLV-----PGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIG 506 + G+ PG PG+ PG +PG VGL G GVG G G Sbjct: 548 FPGQPGMTGRAGSPGRDGHPGL---PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG 604 Query: 507 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 566 P G A + K Q A G G PGL G PG V +PG G+PG Sbjct: 605 PPGYG----PAGPIGDKGQ--AGFPGGPGSPGLPGPKGEPGKIV--PLPGPPGAEGLPGS 656 Query: 567 GAVPGALAAAKAAKYGAAVPGVLGGLGALG--GVGIPG--GVVGA-GPAAAAAAAKAAAK 621 PG + PG+ G GA+G G+G PG G G G + Sbjct: 657 PGFPGP-QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGR 715 Query: 622 AAQFGLVGAAGL-GGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 670 GL G G+ G G G+G+PG+ GL G+P P + GV PG Sbjct: 716 PGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPG 767 Score = 125 bits (313), Expect = 2e-28 Identities = 197/665 (29%), Positives = 229/665 (34%), Gaps = 137/665 (20%) Query: 104 KAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGA 163 K K GL G+ GV G P + G PQ G K G GLPG PGA Sbjct: 45 KGQKGERGLPGLQGVIGF-----PGMQGPEGPQGPPGQK-GDTGEPGLPGTKGTRGPPGA 98 Query: 164 R-FPGVGVLPGVPTGAGVKPKAPGVGG-----------------AFAGIPG--------- 196 +PG LPG+P G P PG+ G FAG PG Sbjct: 99 SGYPGNPGLPGIP-GQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKG 157 Query: 197 -VGPFGGPQPGVPL----GYPIKAPKLPGGYGLPYTTGKL-PYGY----GPGGVAGAAGK 246 G G PG+ L G+P P PG GLP G + P G+ GP G G G+ Sbjct: 158 DPGEILGHVPGMLLKGERGFP-GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGE 216 Query: 247 AGY-------PTG----------TGVGPQAAAAAAAKAAAKFGAGAAGV-----LPGVGG 284 G P G GV QA A K G G +PGVG Sbjct: 217 KGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGE 276 Query: 285 AGVPGVPG--AIPGIGGIAG-------VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG 335 G PG PG PG G G G P + G A P G G Sbjct: 277 KGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336 Query: 336 PGVVGVPG-AGVPGV----GVPG-AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKY 388 G +G G G PG G PG G P +PG G PG VPG + Sbjct: 337 TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDR 396 Query: 389 GARPGVGVGGI--------PTYGVGAGGFPGFGVGV----GGIPGVAGVPGVGGVPGVGG 436 G PG + G P G G PG+ G+ G PG G PG+ G PG G Sbjct: 397 GF-PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 455 Query: 437 VPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 496 G + ++ Y PG PG PG A G PG GV Sbjct: 456 EIGEK-GQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG---RDGVAGV 511 Query: 497 PGVGVAPGI--GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 554 PG PG+ PG + + K G PG G PG+ AG Sbjct: 512 PGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD--------KGDPGF---PGQPGMTGRAGS 560 Query: 555 PGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA 614 PG G+PG PG++ G+ G G GGVG PG GP Sbjct: 561 PGRDGHPGLPGPKGSPGSV-------------GLKGERGPPGGVGFPGSRGDTGPPGPPG 607 Query: 615 AAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLS 674 A G +G G G GG G PG+ G G P G PG S Sbjct: 608 YGPA-------GPIGDKGQAGF-PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPG---S 656 Query: 675 PIFPG 679 P FPG Sbjct: 657 PGFPG 661 Score = 115 bits (289), Expect = 1e-25 Identities = 151/487 (31%), Positives = 185/487 (37%), Gaps = 104/487 (21%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALG--PGGKPLKPVPGGLAGAGLGAG 78 P +PG P PG G PG PG G++GG L PG K + +PG GL Sbjct: 986 PGQPG--PKGDPGISGTPGAPGLPGPK-GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGD 1042 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVV 134 GA G P G+ + K G+ G PG G G P +PG+ Sbjct: 1043 KGAKGE---KGQAGPPGIG--IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS-- 1095 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGA 190 PG PG V G PG LPG + PG+ +PGV AG+ P PG G Sbjct: 1096 --PGLKGSPGSVGYPGSPG------LPGEKGDKGLPGLDGIPGVKGEAGL-PGTPGPTGP 1146 Query: 191 FA--------GIPGVGPFGGPQPGVP-LGYP--------------IKAPKLPGGYGLPYT 227 GIPG G +PG+P G+P + P L G G+P + Sbjct: 1147 AGQKGEPGSDGIPGSAGEKG-EPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGS 1205 Query: 228 TGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGV--LPGVGGA 285 G+ + GP G G G G P GP+ + G G LPG+ G Sbjct: 1206 KGEQGF-MGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGV 1264 Query: 286 ----GVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPG 337 G PG PGA PG+ G G G P + G PG PGF G Sbjct: 1265 KGDKGNPGWPGA-PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-----PGVPGF-QG 1317 Query: 338 VVGVPGA-GVPG----VGVPGA-GIPVVPGA--------GIPGAAVPGVVSPEAAAKAAA 383 G+PG G+ G GVPGA G+P PG G PG +PG P Sbjct: 1318 PKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPG--LPGPEGPPGLKGLQG 1375 Query: 384 KAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----------VGVGGIPGVAGVPGVGGVP 432 G + G+ GIP G G PGF G G G G PG G+P Sbjct: 1376 LPGPKGQQGVTGLVGIP----GPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLP 1431 Query: 433 GVGGVPG 439 G G PG Sbjct: 1432 GSMGPPG 1438 Score = 71.2 bits (173), Expect = 3e-12 Identities = 112/386 (29%), Positives = 137/386 (35%), Gaps = 99/386 (25%) Query: 306 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP----GVVGVPGA-GVPGVGVPGAGIPVVP 360 PAA ++AA G AG G G GV G G G+PG+ Sbjct: 13 PAALLLHEEHSRAAAKGGCAG-----SGCGKCDCHGVKGQKGERGLPGL----------- 56 Query: 361 GAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAGGFPGFGVGV 416 G+ G PG+ PE + G PG+ G G P GA G+PG Sbjct: 57 -QGVIG--FPGMQGPEGPQGPPGQKGDTG-EPGLPGTKGTRGPP----GASGYPGN---- 104 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVG 476 PG+ G+PG G PG G+PG K + L P PG+ PG Sbjct: 105 ---PGLPGIPGQDGPPGPPGIPGCN---------GTKGERGPLGP-----PGL---PGFA 144 Query: 477 VAPGVGLAPGVGVAPG--VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 534 PG PG+ PG +G PG+ L+ G Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGM-------------------------LLKGERGF-P 178 Query: 535 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGA 594 GIPG G+PGL G PG G PG PG + + G + G G G Sbjct: 179 GIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG-----EKGQMGLSFQGPKGDKGD 233 Query: 595 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGIP 653 G G PG G A A K + G G G G+ GVG G PG G G P Sbjct: 234 QGVSGPPG---VPGQAQVQEKGDFATKGEK-GQKGEPGFQGMPGVGEKGEPGKPGPRGKP 289 Query: 654 PAAAAKAAKYGVAARPGFGLSPIFPG 679 K G PGF P +PG Sbjct: 290 ----GKDGDKGEKGSPGFPGEPGYPG 311 Score = 33.1 bits (74), Expect = 0.89 Identities = 41/135 (30%), Positives = 49/135 (36%), Gaps = 29/135 (21%) Query: 28 GVPGAIPGGVPGGVFYPGA-----GLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 GVPGA G+PG PG G L G PG K L+ +PG G+ +G Sbjct: 1335 GVPGA--KGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG-- 1390 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVK 142 PG P G+ G G PG G A P+ P PG Sbjct: 1391 ----IPG---PPGIP-------------GFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430 Query: 143 PGKVPGVGLPGVYPG 157 PG + G P V G Sbjct: 1431 PGSMGPPGTPSVDHG 1445 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 167 bits (424), Expect = 2e-41 Identities = 216/712 (30%), Positives = 265/712 (37%), Gaps = 157/712 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 472 VG GI GVAG PG G+PG G PG I+ + + G V G+ PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV-GLPGDPGLPGQ 688 Query: 473 PGVGVAPGVGLAPGVGVAPGVGV--APGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 PG+ PG PG+ PG+G+ PG PGI GP G Sbjct: 689 PGLPGIPGSKGEPGI---PGIGLPGPPGPKGFPGIPGPPGAPGT---------------- 729 Query: 530 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 589 G GL G PG G PG + G PG +PG A K PG Sbjct: 730 ----PGRIGLEGPPGPPGFPGPKGEPGFAL-PGPPGPPGLPG-FKGALGPKGDRGFPGPP 783 Query: 590 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV----GGLGVPG 645 G G G G+PG GP Q G +G GL G+GV G G+PG Sbjct: 784 GPPGRTGLDGLPGPKGDVGP------------NGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 646 -VG--GLGGIP-------------PAAAAKAAKYGVAARPGFGLSPIFPGGA 681 +G GL GIP P + G+ PG PI P G+ Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG----PIGPPGS 879 Score = 160 bits (405), Expect = 4e-39 Identities = 225/742 (30%), Positives = 273/742 (36%), Gaps = 143/742 (19%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G PG P G PG G L G GALGP G P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR---TGLD 792 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP--QPG 138 P G + P G G G PG+ G+GV P PG P QPG Sbjct: 793 GLPGPK--GDVGPNGQP-------------GPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG- 196 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGT 894 Query: 197 ---VGPFGGPQPGVPLGYPIKA--------PKLPGGYGLPYTTGK--------LPYGYGP 237 +G G P P PLG P ++ L G GLP TG+ LP GP Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Query: 238 G-----GVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGV----GGAGV 287 G G G+ G P GV GP+ +G G LPG G G+ Sbjct: 955 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGPKGNPGL 1013 Query: 288 PGVPGAI--PGIGGIAG-------------------VGTPAAAAAAAAAAKAAKYGAAAG 326 PG PG I PG+ G G G P + G ++ Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073 Query: 327 LVPG--GPGFGPGVVGVPG-AGVPG-VGVPGA-GIPVVPGA----GIPG-AAVPGVVSPE 376 +PG GP PG+ G PG G+ G VG PG G+P PGA G+PG PG P+ Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 377 AAAKAAAKAAKYGARPGVGVGGIPTY-------------GV-------GAGGFPGFG-VG 415 + G VG GG P G+ G G PGFG G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 416 VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 475 G+PG++G G GG+PG+ G PG+ P+ + + PGV PG +PG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGEPG-------FHGFPGVQGPPGPPGSPGP 1245 Query: 476 GVA-----PGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 + PG PG G PG PG+ G GG+ + + Sbjct: 1246 ALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1305 Query: 530 AGLGA----------------GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 G G PGL G PG+ +GVPG G PG PG Sbjct: 1306 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP 1365 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 633 + + G G G G G+ G GP + GL G G Sbjct: 1366 GLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1425 Query: 634 GG-LGVGGL-GVPGVGGLGGIP 653 GG G GL G PG GL G P Sbjct: 1426 GGRKGDPGLPGQPGTRGLDGPP 1447 Score = 156 bits (395), Expect = 5e-38 Identities = 221/714 (30%), Positives = 264/714 (36%), Gaps = 158/714 (22%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPG- 650 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPG----VGLPGVYPGGVLPGARFPGVGVLPGVPTG 177 PG + QPG PG PG VGLPG PG LPG PG LPG+P Sbjct: 651 ----PKGDPGQTITQPGKPGLPGN-PGRDGDVGLPGD-PG--LPGQ--PG---LPGIPGS 697 Query: 178 AGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 237 G GIPG+G P P P G+P +PG G P T G++ GP Sbjct: 698 KGEP-----------GIPGIGL---PGPPGPKGFP----GIPGPPGAPGTPGRIGLE-GP 738 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G G G P GP G G L G G PG PG PG Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLP---------GFKGALGPKGDRGFPGPPGP-PGR 788 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGL----VPGGPGFGPGVVGVPGA-GVPGV--- 349 G+ G+ P G+ PG PG PG +G PG G+PG Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-PGPIGQPGLHGIPGEKGD 847 Query: 350 -GVPGAGIPVVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 G PG +P PG GIPGA PG + P + KA Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGA--PGPIGPPGSPGLPGKA------------------- 886 Query: 405 GAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 GA GFPG +G G PG G+PG GVPG+ G G+ P K +K Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE- 945 Query: 460 VPGVGVAPG------VGVA-----PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GP 507 PG+ PG +G PG+ PGV G PG PG+ PG+ GP Sbjct: 946 -PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004 Query: 508 GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 567 G L GL G PGL +G G GV G +GVPG Sbjct: 1005 PGPKG----------NPGLPGQPGL-IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053 Query: 568 AVPGALAAAKAAKYGAAVPGVLGGLG--ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 PG +PG G G + +G+PG GP Sbjct: 1054 GSPG-------------LPGQKGDKGDPGISSIGLPGL---PGPKGEP------------ 1085 Query: 626 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 GL G G G+ G +G PG+ GL G P A G PGF +P PG Sbjct: 1086 GLPGYPGNPGIK-GSVGDPGLPGLPGTPGAK-------GQPGLPGFPGTPGPPG 1131 Score = 142 bits (357), Expect = 1e-33 Identities = 207/722 (28%), Positives = 262/722 (36%), Gaps = 125/722 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + + A Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG----QKGEKGQAGATGPK 526 Query: 458 GLVPGVGVAPGVGVAPGVGVAPGVGL-------------APGVGVAPGVGVAPGVGVAPG 504 GL PG+ APG PG PG L +PG PG+ PG PG Sbjct: 527 GL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585 Query: 505 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAGVPGLGVG 560 + GP G + K + G G+PG +G PG G G G+ Sbjct: 586 LPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV 639 Query: 561 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 620 AG PG +PG PG+ G G G VG+PG G Sbjct: 640 AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP------- 692 Query: 621 KAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIF 677 G+ G+ G G+ G+G G PG G GI PP A + G+ PG P F Sbjct: 693 -----GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG---PPGF 744 Query: 678 PG 679 PG Sbjct: 745 PG 746 Score = 139 bits (349), Expect = 1e-32 Identities = 199/652 (30%), Positives = 240/652 (36%), Gaps = 137/652 (21%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGP-------QPGVPLGYP-- 212 PG + G P +GV +P +PG+ G G PG+ G P +PG+P GYP Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYPGN 1093 Query: 213 ------IKAPKLPGGYGLPYTTGK--------LPYGYGPGGVAGAAGKAGYPTGTGV--- 255 + P LPG G P G+ P GP G++G G G P G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153 Query: 256 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308 GP + AG G PG G G PG PG +PG+ G G G Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPG-LPGLSGQKGDG---- 1207 Query: 309 AAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGVPGA-GVPGV----GVPGAGIPVVPG 361 GL +PG PG PG G PG G PGV G PG+ P + G Sbjct: 1208 -----------------GLPGIPGNPGL-PGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249 Query: 362 A-------GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAGG 408 G PG P G+ PE G + G G+P G G Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1309 Query: 409 FPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPG 468 PG G G PG+ G+ G G+PGV G PG+ P +A + GL+ G PG Sbjct: 1310 PPGLQ-GNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSGVPGSAGPEGEPGLIGPPG-PPG 1366 Query: 469 VGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLR 527 + G + + G PG+ PG+ PG GP G+ Sbjct: 1367 LPGPSGQSI-----IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN---- 1417 Query: 528 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 579 GL G G G G PGL G GL G G PG + A Sbjct: 1418 ---GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465 Score = 121 bits (304), Expect = 2e-27 Identities = 187/666 (28%), Positives = 228/666 (34%), Gaps = 128/666 (19%) Query: 93 PGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVG 150 PG D + K + GL G PG+ G P P G PG G Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 151 LPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGG-----AFAGIPGVGPFGGP 203 PG LPG FPG LPG+P GA PG G F G PG GP Sbjct: 94 PPG------LPG--FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145 Query: 204 --QPGVP--LGYP--IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVG 256 PG+P G P I LPG G P GY GP G+ G G G P +G Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNP--------GYPGPPGIQGLPGPTGIP--GPIG 195 Query: 257 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI----------PGIGGIAGVGTP 306 P G G++ G G+PG G + G G+ G P Sbjct: 196 P---------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPG-----------AGVPGV-GVP 352 + ++ +PG GP PG+ G PG G PG G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 353 G-------AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYG---ARPGVGVGGIPT 401 G GIP +PG G PG PG + G RPG G+ Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGE--PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEK 358 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG--VGGVPGVGISPEAQAAAAAKAAKYGL 459 +G G PG G G PG+ G PG+ G PG V G PG P + + Sbjct: 359 GNIGLPGLPG-EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417 Query: 460 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA-PGVGVAPGIGPGGVAAAAKSAA 518 +PG PG+ PG PG G + P + PG PG PG + Sbjct: 418 IPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG-SPGDKGLQGEQGV 473 Query: 519 KVAAKAQLRAAAGLG----------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 568 K G G G+PG +G PG G G G+PG Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533 Query: 569 VPGALAAAKAAKYGAAV---PGVLGGLGALGGVGIPG--GVVGA----------GPAAAA 613 PGA + + PG+ G G LG G PG G+ G GP Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP 593 Query: 614 AAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGL 673 + G G GL G +G +G PG G PP + GVA PG Sbjct: 594 GGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFG-----PPGPVGEKGIQGVAGNPG--- 644 Query: 674 SPIFPG 679 P PG Sbjct: 645 QPGIPG 650 Score = 65.1 bits (157), Expect = 2e-10 Identities = 110/393 (27%), Positives = 131/393 (33%), Gaps = 75/393 (19%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 475 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 527 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 528 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 582 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 583 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 642 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 643 VPGVGGLGGIP-----PAAAAKAAKYGVAARPG 670 PG+ GL G P P + + G PG Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 167 bits (424), Expect = 2e-41 Identities = 216/712 (30%), Positives = 265/712 (37%), Gaps = 157/712 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 472 VG GI GVAG PG G+PG G PG I+ + + G V G+ PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV-GLPGDPGLPGQ 688 Query: 473 PGVGVAPGVGLAPGVGVAPGVGV--APGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 PG+ PG PG+ PG+G+ PG PGI GP G Sbjct: 689 PGLPGIPGSKGEPGI---PGIGLPGPPGPKGFPGIPGPPGAPGT---------------- 729 Query: 530 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 589 G GL G PG G PG + G PG +PG A K PG Sbjct: 730 ----PGRIGLEGPPGPPGFPGPKGEPGFAL-PGPPGPPGLPG-FKGALGPKGDRGFPGPP 783 Query: 590 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV----GGLGVPG 645 G G G G+PG GP Q G +G GL G+GV G G+PG Sbjct: 784 GPPGRTGLDGLPGPKGDVGP------------NGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 646 -VG--GLGGIP-------------PAAAAKAAKYGVAARPGFGLSPIFPGGA 681 +G GL GIP P + G+ PG PI P G+ Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG----PIGPPGS 879 Score = 164 bits (415), Expect = 3e-40 Identities = 227/742 (30%), Positives = 273/742 (36%), Gaps = 149/742 (20%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P P G PG P G PG G L G GALGP G P P G G GL Sbjct: 738 PPGPPGFPG--PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR---TGLD 792 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVP--QPG 138 P G + P G G G PG+ G+GV P PG P QPG Sbjct: 793 GLPGPK--GDVGPNGQP-------------GPMGPPGLPGIGVQGPPGPPGIPGPIGQPG 837 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG- 196 PG+ G PG+ G PG R PG+ PG P G P PG GA +G PG Sbjct: 838 LHGIPGEKGDPGPPGLDVPGP-PGERGSPGIPGAPG-PIGPPGSPGLPGKAGA-SGFPGT 894 Query: 197 ---VGPFGGPQPGVPLGYPIKA--------PKLPGGYGLPYTTGK--------LPYGYGP 237 +G G P P PLG P ++ L G GLP TG+ LP GP Sbjct: 895 KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954 Query: 238 G-----GVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGV----GGAGV 287 G G G+ G P GV GP+ +G G LPG G G+ Sbjct: 955 MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPGPKGNPGL 1013 Query: 288 PGVPGAI--PGIGGIAG-------------------VGTPAAAAAAAAAAKAAKYGAAAG 326 PG PG I PG+ G G G P + G ++ Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073 Query: 327 LVPG--GPGFGPGVVGVPG-AGVPG-VGVPGA-GIPVVPGA----GIPG-AAVPGVVSPE 376 +PG GP PG+ G PG G+ G VG PG G+P PGA G+PG PG P+ Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 377 AAAKAAAKAAKYGARPGVGVGGIPTY-------------GV-------GAGGFPGFG-VG 415 + G VG GG P G+ G G PGFG G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 416 VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 475 G+PG++G G GG+PG+ G PG+ P+ + PG PGV PG Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLP-GPKGE-------------PGFHGFPGVQGPPGP 1239 Query: 476 GVAPGVGLA-----PGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 +PG L PG PG PG PG+ G GG+ + + Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1299 Query: 530 AGLGA----------------GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 G G PGL G PG+ +GVPG G PG PG Sbjct: 1300 GDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP 1359 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 633 + + G G G G G+ G GP + GL G G Sbjct: 1360 GLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGA 1419 Query: 634 GG-LGVGGL-GVPGVGGLGGIP 653 GG G GL G PG GL G P Sbjct: 1420 GGRKGDPGLPGQPGTRGLDGPP 1441 Score = 156 bits (395), Expect = 5e-38 Identities = 221/714 (30%), Positives = 264/714 (36%), Gaps = 158/714 (22%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPG- 650 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPG----VGLPGVYPGGVLPGARFPGVGVLPGVPTG 177 PG + QPG PG PG VGLPG PG LPG PG LPG+P Sbjct: 651 ----PKGDPGQTITQPGKPGLPGN-PGRDGDVGLPGD-PG--LPGQ--PG---LPGIPGS 697 Query: 178 AGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 237 G GIPG+G P P P G+P +PG G P T G++ GP Sbjct: 698 KGEP-----------GIPGIGL---PGPPGPKGFP----GIPGPPGAPGTPGRIGLE-GP 738 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G G G P GP G G L G G PG PG PG Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLP---------GFKGALGPKGDRGFPGPPGP-PGR 788 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGL----VPGGPGFGPGVVGVPGA-GVPGV--- 349 G+ G+ P G+ PG PG PG +G PG G+PG Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-PGPIGQPGLHGIPGEKGD 847 Query: 350 -GVPGAGIPVVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 G PG +P PG GIPGA PG + P + KA Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGA--PGPIGPPGSPGLPGKA------------------- 886 Query: 405 GAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 GA GFPG +G G PG G+PG GVPG+ G G+ P K +K Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE- 945 Query: 460 VPGVGVAPG------VGVA-----PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GP 507 PG+ PG +G PG+ PGV G PG PG+ PG+ GP Sbjct: 946 -PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004 Query: 508 GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 567 G L GL G PGL +G G GV G +GVPG Sbjct: 1005 PGPKG----------NPGLPGQPGL-IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053 Query: 568 AVPGALAAAKAAKYGAAVPGVLGGLG--ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 PG +PG G G + +G+PG GP Sbjct: 1054 GSPG-------------LPGQKGDKGDPGISSIGLPGL---PGPKGEP------------ 1085 Query: 626 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 GL G G G+ G +G PG+ GL G P A G PGF +P PG Sbjct: 1086 GLPGYPGNPGIK-GSVGDPGLPGLPGTPGAK-------GQPGLPGFPGTPGPPG 1131 Score = 142 bits (357), Expect = 1e-33 Identities = 207/722 (28%), Positives = 262/722 (36%), Gaps = 125/722 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + + A Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG----QKGEKGQAGATGPK 526 Query: 458 GLVPGVGVAPGVGVAPGVGVAPGVGL-------------APGVGVAPGVGVAPGVGVAPG 504 GL PG+ APG PG PG L +PG PG+ PG PG Sbjct: 527 GL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585 Query: 505 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAGVPGLGVG 560 + GP G + K + G G+PG +G PG G G G+ Sbjct: 586 LPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV 639 Query: 561 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 620 AG PG +PG PG+ G G G VG+PG G Sbjct: 640 AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP------- 692 Query: 621 KAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIF 677 G+ G+ G G+ G+G G PG G GI PP A + G+ PG P F Sbjct: 693 -----GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG---PPGF 744 Query: 678 PG 679 PG Sbjct: 745 PG 746 Score = 141 bits (356), Expect = 2e-33 Identities = 199/646 (30%), Positives = 240/646 (37%), Gaps = 131/646 (20%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGP-------QPGVPLGYP-- 212 PG + G P +GV +P +PG+ G G PG+ G P +PG+P GYP Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYPGN 1093 Query: 213 ------IKAPKLPGGYGLPYTTGK--------LPYGYGPGGVAGAAGKAGYPTGTGV--- 255 + P LPG G P G+ P GP G++G G G P G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153 Query: 256 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308 GP + AG G PG G G PG PG +PG+ G G G Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPG-LPGLSGQKGDG---- 1207 Query: 309 AAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGVPGA-GVPGV----GVPGAGIPVVPG 361 GL +PG PG PG G PG G PGV G PG+ P + G Sbjct: 1208 -----------------GLPGIPGNPGL-PGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249 Query: 362 A-GIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAGGFPGFGV 414 G PG PG+ PE G + G G+P G G PG Sbjct: 1250 PKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQ- 1308 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G PG+ G+ G G+PGV G PG+ P +A + GL+ G PG+ G Sbjct: 1309 GNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSGVPGSAGPEGEPGLIGPPG-PPGLPGPSG 1366 Query: 475 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLG 533 + + G PG+ PG+ PG GP G+ GL Sbjct: 1367 QSI-----IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN-------GL- 1413 Query: 534 AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 579 G G G G PGL G GL G G PG + A Sbjct: 1414 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459 Score = 121 bits (304), Expect = 2e-27 Identities = 187/666 (28%), Positives = 228/666 (34%), Gaps = 128/666 (19%) Query: 93 PGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVG 150 PG D + K + GL G PG+ G P P G PG G Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 151 LPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGG-----AFAGIPGVGPFGGP 203 PG LPG FPG LPG+P GA PG G F G PG GP Sbjct: 94 PPG------LPG--FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145 Query: 204 --QPGVP--LGYP--IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVG 256 PG+P G P I LPG G P GY GP G+ G G G P +G Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNP--------GYPGPPGIQGLPGPTGIP--GPIG 195 Query: 257 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI----------PGIGGIAGVGTP 306 P G G++ G G+PG G + G G+ G P Sbjct: 196 P---------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPG-----------AGVPGV-GVP 352 + ++ +PG GP PG+ G PG G PG G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 353 G-------AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYG---ARPGVGVGGIPT 401 G GIP +PG G PG PG + G RPG G+ Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGE--PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEK 358 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG--VGGVPGVGISPEAQAAAAAKAAKYGL 459 +G G PG G G PG+ G PG+ G PG V G PG P + + Sbjct: 359 GNIGLPGLPG-EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417 Query: 460 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA-PGVGVAPGIGPGGVAAAAKSAA 518 +PG PG+ PG PG G + P + PG PG PG + Sbjct: 418 IPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG-SPGDKGLQGEQGV 473 Query: 519 KVAAKAQLRAAAGLG----------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 568 K G G G+PG +G PG G G G+PG Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533 Query: 569 VPGALAAAKAAKYGAAV---PGVLGGLGALGGVGIPG--GVVGA----------GPAAAA 613 PGA + + PG+ G G LG G PG G+ G GP Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP 593 Query: 614 AAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGL 673 + G G GL G +G +G PG G PP + GVA PG Sbjct: 594 GGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFG-----PPGPVGEKGIQGVAGNPG--- 644 Query: 674 SPIFPG 679 P PG Sbjct: 645 QPGIPG 650 Score = 65.1 bits (157), Expect = 2e-10 Identities = 110/393 (27%), Positives = 131/393 (33%), Gaps = 75/393 (19%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 475 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 527 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 528 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 582 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 583 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 642 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 643 VPGVGGLGGIP-----PAAAAKAAKYGVAARPG 670 PG+ GL G P P + + G PG Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 167 bits (424), Expect = 2e-41 Identities = 216/712 (30%), Positives = 265/712 (37%), Gaps = 157/712 (22%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G PG P G+ G PG G G G G GKP K G G Sbjct: 267 GPPG--PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPG-------------- 310 Query: 87 FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG----LGVSAAPSVPGAVVPQPGAGVK 142 +PG D G G PG G G + P PG V+P+PG G+ Sbjct: 311 -----IPGLPGDP-----------GYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354 Query: 143 PGKVPGVGLPGVYPGGVLPGAR----FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 G+ +GLPG LPG + FPG+ PG+P G P F G G Sbjct: 355 IGEKGNIGLPG------LPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQK 408 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG-----------YGPGGVAGAAGKA 247 GP PG+ + P PG GLP G P G GP G G+ G Sbjct: 409 GDEGP-PGISIPGPPGLDGQPGAPGLPGPPG--PAGPHIPPSDEICEPGPPGPPGSPGDK 465 Query: 248 GYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G GV K F G+ G G+PG+PG +G G Sbjct: 466 GLQGEQGV-------KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-----AGVPG----VGVPGA-GIP 357 A A GA PG PGF PG G PG G+ G +G PGA G+P Sbjct: 519 QAGATGPKGLPGIPGA-----PGAPGF-PGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 358 VVPGAGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--- 413 +PG PG +PG+ P+ + G G+ G+P +G G PGFG Sbjct: 573 GLPGT--PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFGPPG 629 Query: 414 -VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVA 472 VG GI GVAG PG G+PG G PG I+ + + G V G+ PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDV-GLPGDPGLPGQ 688 Query: 473 PGVGVAPGVGLAPGVGVAPGVGV--APGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 PG+ PG PG+ PG+G+ PG PGI GP G Sbjct: 689 PGLPGIPGSKGEPGI---PGIGLPGPPGPKGFPGIPGPPGAPGT---------------- 729 Query: 530 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 589 G GL G PG G PG + G PG +PG A K PG Sbjct: 730 ----PGRIGLEGPPGPPGFPGPKGEPGFAL-PGPPGPPGLPG-FKGALGPKGDRGFPGPP 783 Query: 590 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGV----GGLGVPG 645 G G G G+PG GP Q G +G GL G+GV G G+PG Sbjct: 784 GPPGRTGLDGLPGPKGDVGP------------NGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 646 -VG--GLGGIP-------------PAAAAKAAKYGVAARPGFGLSPIFPGGA 681 +G GL GIP P + G+ PG PI P G+ Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG----PIGPPGS 879 Score = 162 bits (410), Expect = 1e-39 Identities = 212/680 (31%), Positives = 259/680 (38%), Gaps = 93/680 (13%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA----GLGALGG--GALGPGGKPLKPVPGGLAGAGLG 76 P P G+PG G PG PG GL + G G GP G + PG G+ Sbjct: 809 PMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIP 868 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPG---- 131 G PG +PG A+ + K G+ G PG G LG+ VPG Sbjct: 869 GAPGPIGPPGSPG--LPGKAG--ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 132 -AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG- 189 + QPG G+ G PG+ PG PG P + G G+ P PGV G Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGL-PGP--PGPMDPNLLGSKGEKGEPGL-PGIPGVSGP 980 Query: 190 -AFAGIPGVG--PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246 + G+PG P QPG+P G P PK G GLP G + GP G+ G G Sbjct: 981 KGYQGLPGDPGQPGLSGQPGLP-GPP--GPK--GNPGLPGQPGLI----GPPGLKGTIGD 1031 Query: 247 AGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVL--PGVGGAGVPGVPG--------AIP 295 G+P GV GP + + + G G PG+ G+PG+PG P Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091 Query: 296 GIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG-V 349 G GI G VG P + PG PGF PG G PG +G PG Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQ--------PGLPGF-PGTPGPPGPKGISGPPGNP 1142 Query: 350 GVPGAGIPVVPGAGIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGVGGIP----- 400 G+PG PV G G PG P G + A + + G +PG G G P Sbjct: 1143 GLPGEPGPV-GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG-QPGFGNPGPPGLPGL 1200 Query: 401 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV 460 + G GG PG G G+PG G PG G PGV G PG P A + K Sbjct: 1201 SGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG----PPGSPGPALEGPKGNPG 1255 Query: 461 P-GVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAK 515 P G PG PG PG+ G+ G PG+ PG+ GP G+ Sbjct: 1256 PQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1315 Query: 516 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 575 K G PGL G PG+ +GVPG G PG PG Sbjct: 1316 RPGLNGMK-----------GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1364 Query: 576 AKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGG 635 + + G G G G G+ G GP + GL G G GG Sbjct: 1365 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1424 Query: 636 -LGVGGL-GVPGVGGLGGIP 653 G GL G PG GL G P Sbjct: 1425 RKGDPGLPGQPGTRGLDGPP 1444 Score = 156 bits (395), Expect = 5e-38 Identities = 221/714 (30%), Positives = 264/714 (36%), Gaps = 158/714 (22%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGGGALGPGGK 61 G + PG +L + G PGA G+PG PG GL L G PGG Sbjct: 539 GFPGSKGEPGDILTFPGMKGDKGELGSPGA--PGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 62 PLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL 121 K G GL G + PG PG V + K + AG G PG+ G Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGE-----KGIQGVAGNPGQPGIPG- 650 Query: 122 GVSAAPSVPGAVVPQPGAGVKPGKVPG----VGLPGVYPGGVLPGARFPGVGVLPGVPTG 177 PG + QPG PG PG VGLPG PG LPG PG LPG+P Sbjct: 651 ----PKGDPGQTITQPGKPGLPGN-PGRDGDVGLPGD-PG--LPGQ--PG---LPGIPGS 697 Query: 178 AGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 237 G GIPG+G P P P G+P +PG G P T G++ GP Sbjct: 698 KGEP-----------GIPGIGL---PGPPGPKGFP----GIPGPPGAPGTPGRIGLE-GP 738 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G G G P GP G G L G G PG PG PG Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLP---------GFKGALGPKGDRGFPGPPGP-PGR 788 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGL----VPGGPGFGPGVVGVPGA-GVPGV--- 349 G+ G+ P G+ PG PG PG +G PG G+PG Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI-PGPIGQPGLHGIPGEKGD 847 Query: 350 -GVPGAGIPVVPGA----GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 G PG +P PG GIPGA PG + P + KA Sbjct: 848 PGPPGLDVPGPPGERGSPGIPGA--PGPIGPPGSPGLPGKA------------------- 886 Query: 405 GAGGFPGFG-----VGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 GA GFPG +G G PG G+PG GVPG+ G G+ P K +K Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE- 945 Query: 460 VPGVGVAPG------VGVA-----PGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GP 507 PG+ PG +G PG+ PGV G PG PG+ PG+ GP Sbjct: 946 -PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004 Query: 508 GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 567 G L GL G PGL +G G GV G +GVPG Sbjct: 1005 PGPKG----------NPGLPGQPGL-IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQP 1053 Query: 568 AVPGALAAAKAAKYGAAVPGVLGGLG--ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 PG +PG G G + +G+PG GP Sbjct: 1054 GSPG-------------LPGQKGDKGDPGISSIGLPGL---PGPKGEP------------ 1085 Query: 626 GLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 GL G G G+ G +G PG+ GL G P A G PGF +P PG Sbjct: 1086 GLPGYPGNPGIK-GSVGDPGLPGLPGTPGAK-------GQPGLPGFPGTPGPPG 1131 Score = 142 bits (357), Expect = 1e-33 Identities = 207/722 (28%), Positives = 262/722 (36%), Gaps = 125/722 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPG--GLAGAGLGA 77 P P G+ G P G+PG +PG GL + G GA GP G +PG G G Sbjct: 85 PPGPKGIRG--PPGLPG---FPGTPGLPGMPGHDGAPGPQG-----IPGCNGTKGERGFP 134 Query: 78 GLGAFPAVTFPGAL--VPGGVADAAAAYKAAKAGA----------GLGGVPGVGGLGVSA 125 G FP + P +PG + + ++ G G+ G+PG G+ Sbjct: 135 GSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAP 185 P P ++ PG PG +GL P G G P P G + K P Sbjct: 195 GPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQG----PPGPPGQISEQKRP 250 Query: 186 GVGGAF----AGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPG 238 + F G+PG GP G P P G P G G P GK G Sbjct: 251 -IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQP 309 Query: 239 GVAGAAGKAGYPTGTG----VGPQAAAAAAAKAAAKFGAGAAGVLPG-VGGAGVPGVPG- 292 G+ G G GYP G G + G+ G G G+PG+PG Sbjct: 310 GIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 293 ----AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVP 347 PGI G G+ P AA PG PGF PG G G G P Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGP--------------PGPPGF-PGERGQKGDEGPP 414 Query: 348 GVGVPGA----GIPVVPG-AGIPGAAVPGVVSPEAAAKAA-----AKAAKYGARPGVGVG 397 G+ +PG G P PG G PG A P + + + G + GV Sbjct: 415 GISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVK 474 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKY 457 G G F G G+ G PG G+PG+ G PG G PG + + A Sbjct: 475 G----DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG----QKGEKGQAGATGPK 526 Query: 458 GLVPGVGVAPGVGVAPGVGVAPGVGL-------------APGVGVAPGVGVAPGVGVAPG 504 GL PG+ APG PG PG L +PG PG+ PG PG Sbjct: 527 GL-PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG 585 Query: 505 I-GPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGIPGLGVGVGVPGLGV--GAGVPGLGVG 560 + GP G + K + G G+PG +G PG G G G+ Sbjct: 586 LPGPKG------EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGV 639 Query: 561 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAA 620 AG PG +PG PG+ G G G VG+PG G Sbjct: 640 AGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP------- 692 Query: 621 KAAQFGLVGAAGLGGL-GVGGLGVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIF 677 G+ G+ G G+ G+G G PG G GI PP A + G+ PG P F Sbjct: 693 -----GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPG---PPGF 744 Query: 678 PG 679 PG Sbjct: 745 PG 746 Score = 140 bits (352), Expect = 5e-33 Identities = 199/649 (30%), Positives = 240/649 (36%), Gaps = 134/649 (20%) Query: 23 PSRPG-----GVPGAI-PGGVPGGVFYPG-AGLGALGG-----GALGPGGKP-------L 63 P PG G+PGA P G PG PG AG G G +GP G P Sbjct: 856 PGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGR 915 Query: 64 KPVPG-----GLAGA-GLGAGLGAFPAVTFPGALVPGGVADA-AAAYKAAKAGAGLGGVP 116 VPG GL G GL G + PG P G D K K GL G+P Sbjct: 916 SGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 117 GVGG-LGVSAAPSVPG--AVVPQPGAGVKPGKVPGVGLPGVYPG--------GVLPGARF 165 GV G G P PG + QPG PG GLPG PG G + F Sbjct: 976 GVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG-QPGLIGPPGLKGTIGDMGF 1034 Query: 166 PGVGVLPGVPTGAGV--KPKAPGVGGAFA--GIPGVGPFGGP-------QPGVPLGYP-- 212 PG + G P +GV +P +PG+ G G PG+ G P +PG+P GYP Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLP-GYPGN 1093 Query: 213 ------IKAPKLPGGYGLPYTTGK--------LPYGYGPGGVAGAAGKAGYPTGTGV--- 255 + P LPG G P G+ P GP G++G G G P G Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153 Query: 256 -------GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308 GP + AG G PG G G PG PG +PG+ G G G Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGE-PGQPGFGNPGPPG-LPGLSGQKGDG---- 1207 Query: 309 AAAAAAAAKAAKYGAAAGL--VPGGPGFGPGVVGVPGA-GVPGV----GVPGAGIPVVPG 361 GL +PG PG PG G PG G PGV G PG+ P + G Sbjct: 1208 -----------------GLPGIPGNPGL-PGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249 Query: 362 A-GIPGAAVP-------GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAGGFPG 411 G PG P G+ PE G + G G+P G G PG Sbjct: 1250 PKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1309 Query: 412 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGV 471 G G PG+ G+ G G+PGV G PG+ P +A + GL+ G PG+ Sbjct: 1310 LQ-GNPGRPGLNGMKGDPGLPGVPGFPGMK-GPSGVPGSAGPEGEPGLIGPPG-PPGLPG 1366 Query: 472 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAA 530 G + + G PG+ PG+ PG GP G+ Sbjct: 1367 PSGQSI-----IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRN------- 1414 Query: 531 GLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 579 GL G G G G PGL G GL G G PG + A Sbjct: 1415 GL-PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462 Score = 121 bits (304), Expect = 2e-27 Identities = 187/666 (28%), Positives = 228/666 (34%), Gaps = 128/666 (19%) Query: 93 PGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVG 150 PG D + K + GL G PG+ G P P G PG G Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 151 LPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGG-----AFAGIPGVGPFGGP 203 PG LPG FPG LPG+P GA PG G F G PG GP Sbjct: 94 PPG------LPG--FPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGP 145 Query: 204 --QPGVP--LGYP--IKAPKLPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVG 256 PG+P G P I LPG G P GY GP G+ G G G P +G Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNP--------GYPGPPGIQGLPGPTGIP--GPIG 195 Query: 257 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI----------PGIGGIAGVGTP 306 P G G++ G G+PG G + G G+ G P Sbjct: 196 P---------------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPG-----------AGVPGV-GVP 352 + ++ +PG GP PG+ G PG G PG G P Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300 Query: 353 G-------AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYG---ARPGVGVGGIPT 401 G GIP +PG G PG PG + G RPG G+ Sbjct: 301 GKDGENGQPGIPGLPGDPGYPGE--PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEK 358 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG--VGGVPGVGISPEAQAAAAAKAAKYGL 459 +G G PG G G PG+ G PG+ G PG V G PG P + + Sbjct: 359 GNIGLPGLPG-EKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGIS 417 Query: 460 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA-PGVGVAPGIGPGGVAAAAKSAA 518 +PG PG+ PG PG G + P + PG PG PG + Sbjct: 418 IPG---PPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG-SPGDKGLQGEQGV 473 Query: 519 KVAAKAQLRAAAGLG----------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 568 K G G G+PG +G PG G G G+PG Sbjct: 474 KGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPG 533 Query: 569 VPGALAAAKAAKYGAAV---PGVLGGLGALGGVGIPG--GVVGA----------GPAAAA 613 PGA + + PG+ G G LG G PG G+ G GP Sbjct: 534 APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEP 593 Query: 614 AAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGL 673 + G G GL G +G +G PG G PP + GVA PG Sbjct: 594 GGITFKGERGPPGNPGLPGLPG-NIGPMGPPGFG-----PPGPVGEKGIQGVAGNPG--- 644 Query: 674 SPIFPG 679 P PG Sbjct: 645 QPGIPG 650 Score = 65.1 bits (157), Expect = 2e-10 Identities = 110/393 (27%), Positives = 131/393 (33%), Gaps = 75/393 (19%) Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA 354 G+ AG+ A + A AA YG + PG G+ G G G PG+ Sbjct: 5 GVSLAAGLFLLALSLWGQPAEAAACYGCS----PGSKCDCSGIKGEKGERGFPGL----- 55 Query: 355 GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGV 414 G PG +PG PE G R G GIP G G G Sbjct: 56 -------EGHPG--LPGFPGPEGPP---------GPRGQKGDDGIP----GPPGPKGIR- 92 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G+PG G PG+ G+PG G PG P+ + G PG PG+ PG Sbjct: 93 GPPGLPGFPGTPGLPGMPGHDGAPG----PQGIPGCNGTKGERGF-PGSPGFPGLQGPPG 147 Query: 475 VGVAPGVGLAPG---VGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAKVAAKAQLR 527 PG+ PG + PG PG PGI GP G+ Sbjct: 148 PPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP----------- 196 Query: 528 AAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGA-----GVPGFGAVPGALAAAKAAKYG 582 G PGL G PGL G GL G G PG K Sbjct: 197 ------PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP 250 Query: 583 AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLG 642 V G G G G PG GP K + + G G G G G G Sbjct: 251 IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEK--GEKGEQGEPGKRGKPGKD-GENG 307 Query: 643 VPGVGGLGGIP-----PAAAAKAAKYGVAARPG 670 PG+ GL G P P + + G PG Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 167 bits (424), Expect = 2e-41 Identities = 228/723 (31%), Positives = 286/723 (39%), Gaps = 112/723 (15%) Query: 23 PSRPG--GVPGAIPG------GVPGGV----FYPGAGLGALGGGALGPGGKPLKPVPGGL 70 P PG G PG G G+PG + F G+ AL GG GP GK P P GL Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439 Query: 71 AGA--------GL--GAGLGAFPAVT-FPGALVPGGVADAAAAYKAAKAGAGLGGVPGVG 119 G GL G FP + PGA P G A + + + G+PG+ Sbjct: 440 PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLP 499 Query: 120 G----LGVSAAPSVPGAVVPQPGAGVKPG-----KVPG-VGLPGVYPGGVLPGAR---FP 166 G G++ P G PG PG VPG +G PG P G +R Sbjct: 500 GPKGFAGINGEPGRKGD-RGDPGQHGLPGFPGLKGVPGNIGAPG--PKGAKGDSRTITTK 556 Query: 167 GVGVLPGVPTGAGVK--PKAPGVGG--AFAGIPG------VGPFGGP-QPGVPLGYPIKA 215 G PGVP G+K +PG G F G+PG GP G P PG+P Sbjct: 557 GERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPG 616 Query: 216 PKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGA 275 P G GLP G+ + G G+ G G G P G Q K A G Sbjct: 617 EMGPPGLGLPGLKGQRGFP-GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVG-GDRQ 674 Query: 276 AGVLPG-VGG-AGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYG-AAAGLVPGG 331 + PG +GG G+PG+PG PG G G+ G P A A G A PG Sbjct: 675 EAIQPGCIGGPKGLPGLPGP-PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGP 733 Query: 332 PGF-GP----GVVGVPGA-GVPG-VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAAAKAAA 383 PGF GP G VG+PG G PG +G+PG P PG G+PG + P A Sbjct: 734 PGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGP--PGERGLPGEVLGAQPGPRGDA---- 787 Query: 384 KAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS 443 G G+ G+P G G PGF G G+PG+ G+ G G+PG G PG+ Sbjct: 788 -----GVPGQPGLKGLP----GDRGPPGFR-GSQGMPGMPGLKGQPGLPGPSGQPGL--- 834 Query: 444 PEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAP 503 YG PG+ PG APG G+ PG PG PG AP Sbjct: 835 -------------YG-PPGLHGFPG---APGQEGPLGLPGIPGREGLPGDRGDPGDTGAP 877 Query: 504 G-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 562 G +G G++ A + + G G+ G PGL G PG+ G Sbjct: 878 GPVGMKGLSGDRGDAGFTGEQGHPGS-----PGFKGIDGMPGTPGLKGDRGSPGMDGFQG 932 Query: 563 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKAAA 620 +PG PG +K +PG+ G G G G G G G P Sbjct: 933 MPGLKGRPG-FPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKG 991 Query: 621 KAAQFGLVGAAG-LGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFP 678 + G +G G LG G+ G+ G+PG+ G+ G+P G PG P FP Sbjct: 992 EKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFP 1051 Query: 679 GGA 681 G A Sbjct: 1052 GVA 1054 Score = 152 bits (383), Expect = 1e-36 Identities = 233/809 (28%), Positives = 289/809 (35%), Gaps = 190/809 (23%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPG--AGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P RPG V P G PG PG G G LG G V G G G Sbjct: 198 PGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYG-----VKGEKGDVG-QPGPN 251 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPG-A 139 P+ T + P GV YK K G G+ G+ G PG + PG + Sbjct: 252 GIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPG-LRGYPGLS 310 Query: 140 GVK--PGKVPGVGLPGVY--------------PG-----------GVLPGAR----FPGV 168 G K PG+ GL G PG + GAR FPG Sbjct: 311 GEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGA 370 Query: 169 GVLP---GVPTGAGVKPKAPGV----GGAFAGIPG-VGPFGG-PQPGVPLGY-----PIK 214 P G P G+ P PG+ G G+PG +GP G PG+P Y P Sbjct: 371 QGEPGSQGEPGDPGL-PGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDG 429 Query: 215 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGA 273 PG GLP G + +G G G AG G P G GP+ A + G Sbjct: 430 KRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGD 489 Query: 274 GAAGVLPGVGG----AGVPGVPG--------------AIPGIGGIAG-VGTPAAAAAAAA 314 A LPG+ G AG+ G PG PG+ G+ G +G P A Sbjct: 490 EAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGD 549 Query: 315 AAKAAKYGAAA--------------------GL-----VPGGPGFG-------PGVVGVP 342 + G GL +PG PG G PG G+P Sbjct: 550 SRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIP 609 Query: 343 GA-------GVPGVGVPG----------AGIPVVPG-AGIPG-AAVPGVVSPEAAAKAAA 383 G G PG+G+PG AG+P PG G PG A PG + + K A Sbjct: 610 GTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAV 669 Query: 384 KAAKYGA-RPGV-----GVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 432 + A +PG G+ G+ PT G G PGF G G PG G+PG G Sbjct: 670 GGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGF-AGADGGPGPRGLPGDAGRE 728 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG--VGLAPGVGVA 490 G G PG I P A G +G+ PG PG PG +G PG Sbjct: 729 GFPGPPGF-IGPRGSKGAVGLPGPDGSPGPIGL-PGPDGPPGERGLPGEVLGAQPGPRGD 786 Query: 491 PGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLG 549 GV PG+ PG GP G R + G+ G+PGL G PGL Sbjct: 787 AGVPGQPGLKGLPGDRGPPG----------------FRGSQGM-PGMPGL---KGQPGLP 826 Query: 550 VGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 609 +G PGL G+ GF PG + +PG+ G G G G PG GP Sbjct: 827 GPSGQPGLYGPPGLHGFPGAPG-------QEGPLGLPGIPGREGLPGDRGDPGDTGAPGP 879 Query: 610 AAAAAAAKAAAKAAQFGLVGAAGLGGL-GVGGL----------GVPGVGGLGGIP----- 653 + A G G G G G+ G+ G PG+ G G+P Sbjct: 880 VGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGR 939 Query: 654 ---PAAAAKAAKYGVAARPGFGLSPIFPG 679 P + +A +G+ G P F G Sbjct: 940 PGFPGSKGEAGFFGIPGLKGLAGEPGFKG 968 Score = 136 bits (342), Expect = 7e-32 Identities = 224/778 (28%), Positives = 273/778 (35%), Gaps = 172/778 (22%) Query: 26 PGGVPGAI----PGGVPGGVFYPGAGLGALGG--GALGPGGKP-LKPVPGGLAGAGLGAG 78 P G PG I P G PG PG LGA G G G G+P LK +PG G Sbjct: 751 PDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGS 810 Query: 79 LGAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGGL-GVSAAPSVPGAV 133 G PG +PG + + G GL G PG G G P +PG Sbjct: 811 QG------MPG--MPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGRE 862 Query: 134 VPQPGAGVKPGKV--PG-VGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK--PKAPGVG 188 PG PG PG VG+ G+ G A F G PG P G+ P PG+ Sbjct: 863 -GLPGDRGDPGDTGAPGPVGMKGL--SGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLK 919 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G G PG+ F G P L G G P + G+ + +G G+ G AG+ G Sbjct: 920 GD-RGSPGMDGFQG------------MPGLKGRPGFPGSKGEAGF-FGIPGLKGLAGEPG 965 Query: 249 YPTGTG----VGPQAAAAAAAK-----------AAAKFGAGAAGV--LPGVGG-AGVPGV 290 + G GP K K GA G+ +PG+ G +G+PG+ Sbjct: 966 FKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGL 1025 Query: 291 PG---------------AIPGIGGIAGVGTPAAAAA----------AAAAAKAAKYGAAA 325 PG IPG+ G GV P A +A YG Sbjct: 1026 PGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIG 1085 Query: 326 GL-----------VPGGPGFGP--GVVGVPGA-------GVPG-VGVPG-AGIPVVPGA- 362 +PG PG G G+PG G G +G PG G+ V G Sbjct: 1086 ATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPP 1145 Query: 363 GIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV-GVGGI 419 G+ G PG+ P + + G + G G P G GFPG G+ G+ G+ Sbjct: 1146 GLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAP----GLPGFPGLRGIRGLHGL 1201 Query: 420 PGVAGVPG-----VGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 PG G PG + G PG G PG P G G APG PG Sbjct: 1202 PGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQG-APGERGPPG 1260 Query: 475 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI----------GPGGVAAAAKSAAKVAAKA 524 +PG+ PG+ + APG APGI GP G AA S Sbjct: 1261 ---SPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPG 1317 Query: 525 QLRAAAGLG-------------AGIPGLGVGVGVPGLGVGAGVPGLGVG-------AGVP 564 G G+PG G G G G VG G P Sbjct: 1318 APGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTG-AVGDRGPKGPKGDP 1376 Query: 565 GFGAVPGALAAAKAAKYG---AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAK 621 GF PG + A A A PG +G G G G PG + GP A K Sbjct: 1377 GFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGK 1436 Query: 622 AAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 A G G GG+ VPG G G P + G RPG SP PG Sbjct: 1437 A------GPQGRGGVS----AVPGFRGDEG-PIGHQGPIGQEGAPGRPG---SPGLPG 1480 Score = 118 bits (296), Expect = 2e-26 Identities = 212/727 (29%), Positives = 265/727 (36%), Gaps = 120/727 (16%) Query: 44 PGAGLGALGGGALGP--GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAA 101 P G GG P GG+ +P P G G GL FP + G D Sbjct: 41 PCGGRDCSGGCQCYPEKGGRG-QPGPVGPQGYNGPPGLQGFPGLQ-------GRKGD--- 89 Query: 102 AYKAAKAGAGLGGVPG-VGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVL 160 K + G+ G G VG GVS P G + PG G G+ G G Sbjct: 90 --KGERGAPGVTGPKGDVGARGVSGFPGADG-IPGHPGQGGPRGRPGYDGCNGTQGDSGP 146 Query: 161 PGARFPGVGVLPGVPTGAGVKPKAPGVGGAFA-------------GIPGVGPFGGPQPGV 207 G PG G P G K + G +A G PG+ F GP PG Sbjct: 147 QGP--PGSEGFTGPPGPQGPKGQK---GEPYALPKEERDRYRGEPGEPGLVGFQGP-PGR 200 Query: 208 PLGY-----PIKAPKLPGGYGLPYTTGKLPY-GYGPGGVAGAAGKAGYPTGTGVGPQAAA 261 P G+ P+ AP PG G P G+ G G GV G G G P G+ Sbjct: 201 P-GHVGQMGPVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLH 259 Query: 262 AAAAKAAAKF------GAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV----GTPAAA 309 A F G + PG+ G + G G + PG+ G G+ G+P Sbjct: 260 PIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQK 319 Query: 310 AAAAA-------AAKAAKYGAAAGLVPGGPGFGP---------GVVGVPGA-GVPGV-GV 351 + + K A PG P + P G G PGA G PG G Sbjct: 320 GSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGE 379 Query: 352 PG-AGIPVVPGAGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 PG G+P PG I +PG + P+ A YG PG P G Sbjct: 380 PGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGL 439 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG----VGISPEAQAAAAAKAAKYGLVPG 462 G PG + G+ G G G G+PG G G G + E + +A K GL PG Sbjct: 440 PGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIK-GL-PG 497 Query: 463 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVA 521 + PG G+ PG G G+ PG+ PG IG G A + + Sbjct: 498 L---PGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTIT 554 Query: 522 AKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL----GVG----AGVPGFGAVPGAL 573 K + R G+ G+PG+ G PG G PGL G G G PG+ +PG Sbjct: 555 TKGE-RGQPGV-PGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTK 612 Query: 574 AA-AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG-AGPAAA-----------AAAAKA 618 + G +PG+ G G G G+PG G +G GPA A Sbjct: 613 GTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGD 672 Query: 619 AAKAAQFGLVGA-AGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFG 672 +A Q G +G GL GL G G G GL GIP A A G A R GF Sbjct: 673 RQEAIQPGCIGGPKGLPGL-PGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFP 731 Query: 673 LSPIFPG 679 P F G Sbjct: 732 GPPGFIG 738 Score = 106 bits (264), Expect = 8e-23 Identities = 154/492 (31%), Positives = 190/492 (38%), Gaps = 101/492 (20%) Query: 23 PSRPGGVPGA-----IPGGVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLAGAG 74 P RPG + G +PG +PG +PG AG + G G +G G P GL G Sbjct: 1026 PGRPGHIKGVKGDIGVPG-IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGE- 1083 Query: 75 LGAGLGAF----PAVTFPGALVPG--------GVADAAAAY--KAAKAGAGLGGVPGVGG 120 +GA G F + PG PG G+ + K + G G+ GV G Sbjct: 1084 IGA-TGDFGDIGDTINLPGR--PGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG 1140 Query: 121 L----GVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPT 176 + G+ PG P PG+ G++ +GLPG PGA PG LPG P Sbjct: 1141 VQGPPGLKGQTGFPGLTGP-PGS---QGELGRIGLPGGKGDDGWPGA--PG---LPGFPG 1191 Query: 177 GAGVKPK--APGVGGAFAGIPGVGPFGGPQ-PGVP--LGYPIKAPKLPGGYGLPYTTGK- 230 G++ PG G F G PG G P PG P G P +A LPG G+P G Sbjct: 1192 LRGIRGLHGLPGTKG-FPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQ 1250 Query: 231 -LPYGYGPGG---------------VAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAK 270 P GP G ++GA G G P G+ GP +AA +K Sbjct: 1251 GAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSK 1310 Query: 271 FGAGAAGV--LPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLV 328 G G PG G P PG+ G+ G P GA Sbjct: 1311 GDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMG--NTGPTGAVGDRG 1368 Query: 329 PGGPGFGPGVVGVPGAGVPGVGVPG-AGIP----VVPGA-------GIPGAAVPGVVSPE 376 P GP PG G PG VG PG AGIP V PG G PGA PG + P+ Sbjct: 1369 PKGPKGDPGFPGAPGT----VGAPGIAGIPQKIAVQPGTVGPQGRRGPPGA--PGEMGPQ 1422 Query: 377 AAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG-----VGVGGIPGVAGVPGVGGV 431 + G R G G G G PGF +G G G G PG G Sbjct: 1423 GPP------GEPGFRGAPGKAGPQGRG-GVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGS 1475 Query: 432 PGVGGVPGVGIS 443 PG+ G+PG +S Sbjct: 1476 PGLPGMPGRSVS 1487 Score = 62.4 bits (150), Expect = 1e-09 Identities = 95/308 (30%), Positives = 110/308 (35%), Gaps = 58/308 (18%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLG 80 P PG PG G PG PG L G PG K + PG G GL Sbjct: 1208 PGSPGSDIHGDPGFPGPPGERGDPGEA-NTLPGPVGVPGQKGDQGAPGERGPPG-SPGLQ 1265 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVPQPGA 139 FP +T P + + G D G PG+ GL G P PG+ PG+ Sbjct: 1266 GFPGIT-PPSNISGAPGDK--------------GAPGIFGLKGYRGPPGPPGSAA-LPGS 1309 Query: 140 GVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGV--------------PTGA--GVK 181 G G PG + G P R PGV LPG PTGA Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQGR-PGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 182 PKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 PK P F G PG VG PG+ G P K PG G G P G G Sbjct: 1369 PKGPKGDPGFPGAPGTVGA-----PGIA-GIPQKIAVQPGTVGPQGRRGP-PGAPGEMGP 1421 Query: 241 AGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGV--------LPG-VGGAGVPGV 290 G G+ G+ G GPQ +A + G G PG G G+PG+ Sbjct: 1422 QGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGM 1481 Query: 291 PGAIPGIG 298 PG IG Sbjct: 1482 PGRSVSIG 1489 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 165 bits (418), Expect = 1e-40 Identities = 223/700 (31%), Positives = 254/700 (36%), Gaps = 101/700 (14%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 411 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVS 124 P A FPG P G A G G PG+ G G Sbjct: 412 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL----GPKGQTGEPGIAGFKGEQ 467 Query: 125 AAPSVPGAVVPQ--PGAGVKPGKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGV 180 PG PQ PG + GK G P GV P G PG R PG PG AG Sbjct: 468 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGP 526 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPG 238 K APG G +G+ G G PG P P LPG GL G P G GP Sbjct: 527 K-GAPGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPS 578 Query: 239 GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPG 296 G G G+ G P GPQ A GA G G G+PG PG +PG Sbjct: 579 GAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 633 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGA 354 G G P A A + + GA PG GF PG G PG G G PG Sbjct: 634 KDGETGAAGP--PGPAGPAGERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG- 681 Query: 355 GIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 G+PG A PG+V P + GA+ G G+P G P Sbjct: 682 ------DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGA 733 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGV 465 G G PG G PG+ G+PG G G+ + + A K GL +G Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG- 792 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKA 524 PG A G G PG + G APG G GP G A + + AK Sbjct: 793 PPGPAGANGEKGEVG---PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 849 Query: 525 QLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 583 + A G AG PG G PG GV G G G PGA Sbjct: 850 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG---PKGARGAQGPPGA----------T 896 Query: 584 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGL 641 PG G +G G G PG GP+ A + G G GL G G Sbjct: 897 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956 Query: 642 GVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIFPG 679 G PG G G PP A + G+ PG FPG Sbjct: 957 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996 Score = 151 bits (381), Expect = 2e-36 Identities = 226/689 (32%), Positives = 255/689 (37%), Gaps = 117/689 (16%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 497 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 550 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGG-LGVSAAPSVPGAVVPQPG 138 PGA + G DA K +GA G G PG G G P V G P+ G Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-G 609 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GI 194 A +PGK GLPG PG+ LPG TGA P G G G Sbjct: 610 ANGEPGKAGEKGLPGA-----------PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Query: 195 PGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 254 PG F G PG P G P + K PG G+P G P GP G G G+ G P G Sbjct: 659 PGPSGFQG-LPGPP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQG 714 Query: 255 V-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAA 308 + GP+ K +G AG PG G G+PG GA GI G G G Sbjct: 715 LQGPRGLPGTPGTDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGE 772 Query: 309 AAAAAAAAKAAKYGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG- 353 A K G + P GP PG G GA G PG G PG Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832 Query: 354 AGIPVVPGA-GIPG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI 399 AG PGA G PG A PG P A G + G G Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892 Query: 400 PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 P GA GFPG G G PG G PG G PG G G + +A + GL Sbjct: 893 P----GATGFPG-AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGL 946 Query: 460 -----VPGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAA 513 PG PG G PG GLA G+ G+ G PG+ PG Sbjct: 947 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEP 1004 Query: 514 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 K A A+ + G PG VG PGL AG PG G PG PG Sbjct: 1005 GKQGAPGASGDR---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRD 1049 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG- 632 A A V G G GA+G G PG GPA +A G +G +G Sbjct: 1050 GA-------AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1102 Query: 633 LGGLGV----------GGLGVPGVGGLGG 651 G G+ G G PG GL G Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKG 1131 Score = 147 bits (371), Expect = 3e-35 Identities = 231/743 (31%), Positives = 260/743 (34%), Gaps = 133/743 (17%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 118 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 163 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPG 144 PG P G + A AG G G LGV P P PG PG Sbjct: 164 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219 Query: 145 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGP 203 G PG PG PGV P P G P PG G AG PG G G P Sbjct: 220 PQGFQGNPGE------PGE--PGVSG-PMGPRGPPGPPGKPGDDGE-AGKPGKAGERGPP 269 Query: 204 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P G+P P LPG G G L G G G G++G P G GP Sbjct: 270 GPQGARGFP-GTPGLPGVKGHRGYPG-LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 327 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 322 + AGAAG G G G PG + GG G P A A G Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387 Query: 323 AAAGL----VPGGPG-----FGPGVVGVPG----AGVPGV-GVPG----AGIPVVPGA-- 362 A PG PG PG G+PG AG PG+ G PG G P GA Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 447 Query: 363 --------GIPGAA----------VPGVVSPEAAAKAAAKAAKYGAR--PGVGVGGIPTY 402 G PG A PG P+ A A + K GAR PG GVG I Sbjct: 448 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPP 506 Query: 403 G----VGAGGFPGFG--------------------VGVGGIPGVAGVPGVGGVPGVGGVP 438 G G GFPG G G PG G PG+ G G+ G P Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566 Query: 439 GVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA---PGVGVAPGVGV 495 G P+ + + + G PG G PGV PG A PG G+ Sbjct: 567 G-DAGPQGKVGPSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG 624 Query: 496 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGVPG 547 APG+ PG G G A A + + A G G PG G G G Sbjct: 625 APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG 684 Query: 548 LGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG- 602 + AG PGL VG G PG PGA + + PG G GA G G PG Sbjct: 685 VPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGA 742 Query: 603 -------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GGLGV-GGLGVPGVGGLGGI 652 G+ G AA A K + G GA G GG G+ G +G PG G G Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802 Query: 653 -----PPAAAAKAAKYGVAARPG 670 PP A A G G Sbjct: 803 KGEVGPPGPAGSAGARGAPGERG 825 Score = 143 bits (361), Expect = 5e-34 Identities = 223/713 (31%), Positives = 258/713 (36%), Gaps = 114/713 (15%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLGA 77 P G PG PG G+PG G A G +GP G P +P P G GA Sbjct: 541 PKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP 599 Query: 78 GLGAFPAVT-------------FPGAL----VPGGVADAAAAYKAAKAG-AGLGGVPGVG 119 G+ FP PGA +PG + AA AG AG G G Sbjct: 600 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 659 Query: 120 G-LGVSAAPSVPGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-F 165 G G P PG PG G KPG VPG G PG+ +PG PGA+ Sbjct: 660 GPSGFQGLPGPPGP----PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715 Query: 166 PGVGVLPGVPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGY 211 G LPG P G K + PG G G+PG GP G + V Sbjct: 716 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKG 774 Query: 212 PIKAPKLPGGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P AP GG GL G P G GP G AG+AG G P G GP A Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 834 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAK 317 A A GA G G G G PG PG G GV P A A Sbjct: 835 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 894 Query: 318 AAKYGAAAGLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPG 366 A + AAG V P G PG G PG G G G PG AG P + G AG PG Sbjct: 895 ATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 954 Query: 367 A-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 PG P A G R G+ G+P G GFPG +PG +G Sbjct: 955 EKGEPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGE 1003 Query: 426 PGVGGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGL 483 PG G PG G G + P A + + G +PG PG A GV Sbjct: 1004 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKG 1056 Query: 484 APGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVG 542 G A G APG +PG P G + A+ + + GA GI G Sbjct: 1057 DRGETGAVGAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114 Query: 543 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGA 594 G G G GL G G +PG A+ A G PG +G G Sbjct: 1115 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1174 Query: 595 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 647 G GIPG + GP + A G G G G G+ G+G Sbjct: 1175 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1227 Score = 122 bits (306), Expect = 1e-27 Identities = 159/504 (31%), Positives = 180/504 (35%), Gaps = 49/504 (9%) Query: 215 APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY------PTGTGVGPQAAAAAAAKAA 268 +P++P G P L G G G G+ G P G GPQ A Sbjct: 77 SPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPP-GPQGPAGEQGPRG 135 Query: 269 AKFGAGAAGVLPGVGGA----GVPGVPG--AIPGIGGIAGVGTPAAAAAAAA---AAKAA 319 + G G PG G G PG PG PG G G+G AA A A A Sbjct: 136 DRGDKGEKGA-PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGA 194 Query: 320 KYGAAAG-LVPGGPGFGPGVVGVPG----AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVV 373 + G G + P GP PG G PG G PG G PG P+ P G PG PG Sbjct: 195 QLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP-RGPPGP--PGKP 251 Query: 374 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 433 + A KA + G G G P G G PG G G PG+ G G G PG Sbjct: 252 GDDGEAGKPGKAGERGPPGPQGARGFP----GTPGLPGV-KGHRGYPGLDGAKGEAGAPG 306 Query: 434 V---GGVPGVGISPEAQAAAAAKAAKYGLVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVG 488 V G PG SP + P G A G PG PG VG A G G Sbjct: 307 VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPG 366 Query: 489 VAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPG 547 G G GP G + A+ G GIPG G PG Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426 Query: 548 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVV 605 + AG PG G PG G L K PG+ G G G G PG G Sbjct: 427 I---AGAPGFPGPRGPPGPQGATGPL----GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479 Query: 606 GA-GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYG 664 GA GPA A + G +G G G G G PG GL G P A + G Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERG-APGNRGFPGQDGLAG-PKGAPGERGPSG 537 Query: 665 VAARPGFGLSPIFPGGACLGKACG 688 +A G P PG L A G Sbjct: 538 LAGPKGANGDPGRPGEPGLPGARG 561 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 165 bits (418), Expect = 1e-40 Identities = 223/700 (31%), Positives = 254/700 (36%), Gaps = 101/700 (14%) Query: 26 PGGVPGAI-PGGVPGGVFYPGAG-----LGALGG-GALGPGGKPLKPVPGGLAGAGLGAG 78 P G PG + P G PG PGA GA G GA GP G+P P G AGA G Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPG 342 Query: 79 LGAFP-------------AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVS 124 P A FPG P G A G G PG+ G G Sbjct: 343 TDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL----GPKGQTGEPGIAGFKGEQ 398 Query: 125 AAPSVPGAVVPQ--PGAGVKPGKVPGVGLP-GVYPGGVLPGAR-FPGVGVLPGVPTGAGV 180 PG PQ PG + GK G P GV P G PG R PG PG AG Sbjct: 399 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP-PGERGAPGNRGFPGQDGLAGP 457 Query: 181 KPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKL-PYG-YGPG 238 K APG G +G+ G G PG P P LPG GL G P G GP Sbjct: 458 K-GAPGERGP-SGLAGPKGANG-DPGRP-----GEPGLPGARGLTGRPGDAGPQGKVGPS 509 Query: 239 GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPG 296 G G G+ G P GPQ A GA G G G+PG PG +PG Sbjct: 510 GAPGEDGRPGPP-----GPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 564 Query: 297 IGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGVGVPGA 354 G G P A A + + GA PG GF PG G PG G G PG Sbjct: 565 KDGETGAAGP--PGPAGPAGERGEQGA-----PGPSGFQGLPGPPGPPGEG----GKPG- 612 Query: 355 GIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG 413 G+PG A PG+V P + GA+ G G+P G P Sbjct: 613 ------DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--GTPGTDGPKGA 664 Query: 414 VGVGGIPGVAGVPGVGGVPGVGGVPGVG--------ISPEAQAAAAAKAAKYGLVPGVGV 465 G G PG G PG+ G+PG G G+ + + A K GL +G Sbjct: 665 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG- 723 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKA 524 PG A G G PG + G APG G GP G A + + AK Sbjct: 724 PPGPAGANGEKGEVG---PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 780 Query: 525 QLRAAAGLG-AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 583 + A G AG PG G PG GV G G G PGA Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTG---PKGARGAQGPPGA----------T 827 Query: 584 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLG--VGGL 641 PG G +G G G PG GP+ A + G G GL G G Sbjct: 828 GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887 Query: 642 GVPGVGGLGGI--PPAAAAKAAKYGVAARPGFGLSPIFPG 679 G PG G G PP A + G+ PG FPG Sbjct: 888 GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927 Score = 151 bits (381), Expect = 2e-36 Identities = 226/689 (32%), Positives = 255/689 (37%), Gaps = 117/689 (16%) Query: 26 PGGV-PGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGA-GLGAGLGA 81 PGGV P PG G PG +PG G GP G P + P GLAG G G Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQD------GLAGPKGAPGERGPSGLAGPKGANGDPGR 481 Query: 82 FPAVTFPGAL-VPGGVADAAAAYKAAKAGA-GLGGVPGVGG-LGVSAAPSVPGAVVPQPG 138 PGA + G DA K +GA G G PG G G P V G P+ G Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK-G 540 Query: 139 AGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVP--TGAGVKPKAPGVGGAFA--GI 194 A +PGK GLPG PG+ LPG TGA P G G G Sbjct: 541 ANGEPGKAGEKGLPGA-----------PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Query: 195 PGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG 254 PG F G PG P G P + K PG G+P G P GP G G G+ G P G Sbjct: 590 PGPSGFQG-LPGPP-GPPGEGGK-PGDQGVPGEAGA-PGLVGPRGERGFPGERGSPGAQG 645 Query: 255 V-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPGAIPGIGGIAG-VGTPAA 308 + GP+ K +G AG PG G G+PG GA GI G G G Sbjct: 646 LQGPRGLPGTPGTDGPKGASGPAGP-PGAQGPPGLQGMPGERGA-AGIAGPKGDRGDVGE 703 Query: 309 AAAAAAAAKAAKYGAAAGLVPGGPGFG---------PGVVGVPGA-GVPG----VGVPG- 353 A K G + P GP PG G GA G PG G PG Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763 Query: 354 AGIPVVPGA-GIPG-------------AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI 399 AG PGA G PG A PG P A G + G G Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823 Query: 400 PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 P GA GFPG G G PG G PG G PG G G + +A + GL Sbjct: 824 P----GATGFPG-AAGRVGPPGSNGNPGPPGPPGPSGKDGPK-GARGDSGPPGRAGEPGL 877 Query: 460 -----VPGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAA 513 PG PG G PG GLA G+ G+ G PG+ PG Sbjct: 878 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV-GLPGQRGERGFPGL-PGPSGEP 935 Query: 514 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 K A A+ + G PG VG PGL AG PG G PG PG Sbjct: 936 GKQGAPGASGDR---------GPPG---PVGPPGLTGPAGEPG---REGSPGADGPPGRD 980 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG- 632 A A V G G GA+G G PG GPA +A G +G +G Sbjct: 981 GA-------AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1033 Query: 633 LGGLGV----------GGLGVPGVGGLGG 651 G G+ G G PG GL G Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKG 1062 Score = 147 bits (371), Expect = 3e-35 Identities = 231/743 (31%), Positives = 260/743 (34%), Gaps = 133/743 (17%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 P G PG P G P G P G G GA GP G+ +P G G Sbjct: 49 PKGPPG--PQG-PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGP----------- 94 Query: 85 VTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPG 144 PG P G + A AG G G LGV P P PG PG Sbjct: 95 ---PGPPGPPGPPGLGGNFAAQMAG-GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150 Query: 145 KVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGP 203 G PG PG PGV P P G P PG G AG PG G G P Sbjct: 151 PQGFQGNPGE------PGE--PGVSG-PMGPRGPPGPPGKPGDDGE-AGKPGKAGERGPP 200 Query: 204 QPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P G+P P LPG G G L G G G G++G P G GP Sbjct: 201 GPQGARGFP-GTPGLPGVKGHRGYPG-LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 258 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYG 322 + AGAAG G G G PG + GG G P A A G Sbjct: 259 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318 Query: 323 AAAGL----VPGGPG-----FGPGVVGVPG----AGVPGV-GVPG----AGIPVVPGA-- 362 A PG PG PG G+PG AG PG+ G PG G P GA Sbjct: 319 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 378 Query: 363 --------GIPGAA----------VPGVVSPEAAAKAAAKAAKYGAR--PGVGVGGIPTY 402 G PG A PG P+ A A + K GAR PG GVG I Sbjct: 379 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPP 437 Query: 403 G----VGAGGFPGFG--------------------VGVGGIPGVAGVPGVGGVPGVGGVP 438 G G GFPG G G PG G PG+ G G+ G P Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 497 Query: 439 GVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA---PGVGVAPGVGV 495 G P+ + + + G PG G PGV PG A PG G+ Sbjct: 498 G-DAGPQGKVGPSGAPGEDGR-PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPG 555 Query: 496 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------AGIPGLGVGVGVPG 547 APG+ PG G G A A + + A G G PG G G G Sbjct: 556 APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG 615 Query: 548 LGVGAGVPGLGVG----AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG- 602 + AG PGL VG G PG PGA + + PG G GA G G PG Sbjct: 616 VPGEAGAPGL-VGPRGERGFPGERGSPGA-QGLQGPRGLPGTPGTDGPKGASGPAGPPGA 673 Query: 603 -------GVVGAGPAAAAAAAKA-AAKAAQFGLVGAAGL-GGLGV-GGLGVPGVGGLGGI 652 G+ G AA A K + G GA G GG G+ G +G PG G G Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733 Query: 653 -----PPAAAAKAAKYGVAARPG 670 PP A A G G Sbjct: 734 KGEVGPPGPAGSAGARGAPGERG 756 Score = 143 bits (361), Expect = 5e-34 Identities = 223/713 (31%), Positives = 258/713 (36%), Gaps = 114/713 (15%) Query: 23 PSRPGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPL---KPVPGGLAGAGLGA 77 P G PG PG G+PG G A G +GP G P +P P G GA Sbjct: 472 PKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQP 530 Query: 78 GLGAFPAVT-------------FPGAL----VPGGVADAAAAYKAAKAG-AGLGGVPGVG 119 G+ FP PGA +PG + AA AG AG G G Sbjct: 531 GVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAP 590 Query: 120 G-LGVSAAPSVPGAVVPQPGAGVKPGK--VPG-VGLPGV--------YPGGV-LPGAR-F 165 G G P PG PG G KPG VPG G PG+ +PG PGA+ Sbjct: 591 GPSGFQGLPGPPGP----PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646 Query: 166 PGVGVLPGVPTGAGVKPKA-----PGVGG--AFAGIPG-------VGPFGGPQPGVPLGY 211 G LPG P G K + PG G G+PG GP G + V Sbjct: 647 QGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP-KGDRGDVGEKG 705 Query: 212 PIKAPKLPGGYGLPYTTGKL-PYG-------YGPGGVAGAAGKAGYPTGTG-VGPQAAAA 262 P AP GG GL G P G GP G AG+AG G P G GP A Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765 Query: 263 AAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGVGTPAAAAAAAAAAK 317 A A GA G G G G PG PG G GV P A A Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 825 Query: 318 AAKYGAAAGLV-PGGPGFGPGVVGVPGA----GVPGV----GVPG-AGIPVVPG-AGIPG 366 A + AAG V P G PG G PG G G G PG AG P + G AG PG Sbjct: 826 ATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPG 885 Query: 367 A-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 PG P A G R G+ G+P G GFPG +PG +G Sbjct: 886 EKGEPGDDGPSGAEGPPGPQGLAGQR---GIVGLPGQR-GERGFPG-------LPGPSGE 934 Query: 426 PGVGGVPGVGGVPGVG--ISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGL 483 PG G PG G G + P A + + G +PG PG A GV Sbjct: 935 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG-------SPGADGPPGRDGAAGVKG 987 Query: 484 APGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVG 542 G A G APG +PG P G + A+ + + GA GI G Sbjct: 988 DRGETGAVGAPGAPGPPGSPG--PAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045 Query: 543 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGA-AVPGVLGGLGA 594 G G G GL G G +PG A+ A G PG +G G Sbjct: 1046 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105 Query: 595 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVG 647 G GIPG + GP + A G G G G G+ G+G Sbjct: 1106 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLG 1158 Score = 120 bits (302), Expect = 3e-27 Identities = 152/476 (31%), Positives = 170/476 (35%), Gaps = 47/476 (9%) Query: 237 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA----GVPGVPG 292 PG + G G P GPQ A + G G PG G G PG PG Sbjct: 40 PGDIKDIVGPKGPP-----GPQGPAGEQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGNPG 93 Query: 293 --AIPGIGGIAGVGTPAAAAAAAA---AAKAAKYGAAAG-LVPGGPGFGPGVVGVPG--- 343 PG G G+G AA A A A+ G G + P GP PG G PG Sbjct: 94 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 153 Query: 344 -AGVPG-VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401 G PG G PG P+ P G PG PG + A KA + G G G P Sbjct: 154 FQGNPGEPGEPGVSGPMGP-RGPPGP--PGKPGDDGEAGKPGKAGERGPPGPQGARGFP- 209 Query: 402 YGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAAAAAKAAKYG 458 G G PG G G PG+ G G G PGV G PG SP + Sbjct: 210 ---GTPGLPGV-KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265 Query: 459 LVP-GVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKS 516 P G A G PG PG VG A G G G G GP G Sbjct: 266 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325 Query: 517 AAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 575 + A+ G GIPG G PG+ AG PG G PG G L Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI---AGAPGFPGPRGPPGPQGATGPL-- 380 Query: 576 AKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA-GPAAAAAAAKAAAKAAQFGLVGAAG 632 K PG+ G G G G PG G GA GPA A + G +G G Sbjct: 381 --GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 438 Query: 633 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 688 G G G PG GL G P A + G+A G P PG L A G Sbjct: 439 ERG-APGNRGFPGQDGLAG-PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 162 bits (410), Expect = 1e-39 Identities = 237/726 (32%), Positives = 276/726 (38%), Gaps = 131/726 (18%) Query: 23 PSRPGGVPGAIPGGVPG--GVF---YPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGL 75 P+ P G PG P G PG G F Y G G+G G G +GP G P G AGA Sbjct: 58 PTGPPGPPG--PPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPP------GAAGAPG 109 Query: 76 GAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG-AGLGGVPGVGGLGVSAAPSVPGAVV 134 G PA PG PG A A A G AG G PG G P G V Sbjct: 110 PQGFQG-PAGE-PGE--PGQTGPAGARGPAGPPGKAGEDGHPGKPG-----RPGERGVVG 160 Query: 135 PQPGAGVKPGKVPGV-GLPGVYPGGVLPGAR----FPGVGVLPGVP--------TGAGVK 181 PQ GA PG PG+ G G+ L G + PGV PG P TGA Sbjct: 161 PQ-GARGFPG-TPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGL 218 Query: 182 P------KAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY-- 233 P APG GA VGP G P G PI + PG G P G++ Sbjct: 219 PGERGRVGAPGPAGARGSDGSVGPVG------PAG-PIGSAGPPGFPGAPGPKGEIGAVG 271 Query: 234 GYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVP 291 GP G AG G+ G P +G VGP A AK GAAG LPGV GA G+PG P Sbjct: 272 NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAK---GAAG-LPGVAGAPGLPG-P 326 Query: 292 GAIPGIGGIAG-------VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-----FGP--- 336 IPG G AG VG P A + + + G+A P GP GP Sbjct: 327 RGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGE 386 Query: 337 -GVVGVPG----AGVPGV-GVPG----AGIPVVPG----------------AGIPGAAVP 370 G G PG G PG G+PG AG+ PG AG PG P Sbjct: 387 AGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGE--P 444 Query: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGI-----PTYGVGAGGFPGFGVGVGGIPGVAGV 425 G++ P + G VG+ GI P GA G PG +G G G G Sbjct: 445 GLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPG-NIGFPGPKGPTGD 503 Query: 426 PGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGV-----APGVGVAPG-VGV 477 PG G G G+ G P+ A G+ G G PG PG G Sbjct: 504 PGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGP 563 Query: 478 APGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-AGI 536 A VG G+ G+ G GP G + AA + ++ G G Sbjct: 564 AGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGE 623 Query: 537 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 596 PG+ VG G +G+PG AG+PG K K + G +G G G Sbjct: 624 PGVVGAVGTAGPSGPSGLPGERGAAGIPG----------GKGEKGEPGLRGEIGNPGRDG 673 Query: 597 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAA 656 G PG V GPA A A A G G G G G +G G G G AA Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG-ERGEVGPAGPNGFAGPAGAA 732 Query: 657 AAKAAK 662 AK Sbjct: 733 GQPGAK 738 Score = 157 bits (398), Expect = 2e-38 Identities = 227/705 (32%), Positives = 264/705 (37%), Gaps = 92/705 (13%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 P G PG G PG PGA A G +GP G P G+ G AG P + Sbjct: 392 PPGPPGL--RGSPGSRGLPGADGRA---GVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 86 TFPGALVPGGVADAAAAYKAAKAGA-GLGGVPG-VGGLGVSAAPSVPGAVVPQPGAGVKP 143 P L PG + A K G G+ G PG +G G P G P+ G P Sbjct: 447 MGPRGL-PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTG-DP 504 Query: 144 GKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAGVKPKAPGVGGAFA--GIPGVGPF 200 GK G G L GAR PG P GA P GV G G PG F Sbjct: 505 GKNGDKGHAG------LAGARGAPG----PDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554 Query: 201 GG-PQPGVPLGYPIKAPK--LPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTG-- 254 G P P P G K + L G +GLP G P G GP G +GAAG G P G+ Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAG--PRGERGPPGESGAAGPTG-PIGSRGP 611 Query: 255 ---------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGI 297 VG A + + GAAG+ G G G PG+ G I PG Sbjct: 612 SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGR 671 Query: 298 GGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G G A A A + GAA P GP PG G G P AG Sbjct: 672 DGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGA 731 Query: 357 PVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGV----GVGGIPTYGVGAG 407 PGA G GA P GVV P AA A G PG G GG P G Sbjct: 732 AGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP-PGPAGSRGDGGPP----GMT 786 Query: 408 GFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGV 465 GFPG G G PG +G+ G G PG G G+ P + + G V PG Sbjct: 787 GFPG-AAGRTGPPGPSGISGPPGPPGPAGKEGLR-GPRGDQGPVGRTGEVGAVGPPGFAG 844 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-------VGVAPGIG-PGGVAAAAKSA 517 G G PG G+ APG+ PG GVA +G PG + A Sbjct: 845 EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904 Query: 518 AKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 577 A+ A + G+ G PG G PG G PG G G PG + Sbjct: 905 ARGPPGAV--GSPGVN-GAPGEAGRDGNPG---NDGPPGRDGQPGHKGERGYPGNIGPVG 958 Query: 578 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGL 636 A A PG G +G G G G +GP A A + G+ G G G Sbjct: 959 A----AGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014 Query: 637 GVGGL-GVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGG 680 G GL G+ G GL G+P A +G PG + P P G Sbjct: 1015 GPRGLPGLKGHNGLQGLP----GIAGHHGDQGAPG-SVGPAGPRG 1054 Score = 154 bits (389), Expect = 3e-37 Identities = 229/734 (31%), Positives = 256/734 (34%), Gaps = 100/734 (13%) Query: 3 GLTAAAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGK 61 GL A R GV+ G PG+ P GV P G G G +GP G Sbjct: 406 GLPGADGRAGVM-------------GPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGL 452 Query: 62 PLKPVPGGLAGAGLGAGLGAF--------PA--------VTFPGALVPGGVADAAAAYKA 105 P P G AG GL PA + FPG P G D Sbjct: 453 PGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTG--DPGKNGDK 510 Query: 106 AKAG-AGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVY-PGGVL--P 161 AG AG G PG G + P P V G PG GLPG P G + P Sbjct: 511 GHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKP 570 Query: 162 GAR-FPGVGVLPGV--PTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-----I 213 G R G LPG P G P G G I GP G P P G P + Sbjct: 571 GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV 630 Query: 214 KAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAK 270 G GLP G +P G G G G G+ G P G G A A A A Sbjct: 631 GTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGAT 690 Query: 271 FGAGAAGVLPGVGGAGVPGVPGAIPGIG--GIAGVGTPAAAAAAAAA-----AKAAK--- 320 G AG G AG G PG +G G G PA AA A AK K Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGEN 750 Query: 321 -----YGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIPGAAVPGVV 373 G P GP PG G G G P PG G P G G PG + G+ Sbjct: 751 GVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGP----PGMTGFPGAAGRTGPPGPS--GIS 804 Query: 374 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--------VGVGGIPGVAGV 425 P A K G R G G T VGA G PGF G G PG G Sbjct: 805 GPPGPPGPAGKEGLRGPRGDQGPVG-RTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGP 863 Query: 426 PGVGGVPGVGGVPGV----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGV 481 G+ G PG+ G+PG G+ A A PG PG +PGV APG Sbjct: 864 QGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGE 923 Query: 482 GLA---PGVGVAPGVGVAPGV----GVAPGIGPGGVAAAAKSAAKV--AAKAQLRAAAGL 532 PG PG PG G IGP G A A V A K R G Sbjct: 924 AGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETG- 982 Query: 533 GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL 592 +G G VG G +G G+ G PG P L K +PG+ G Sbjct: 983 PSGPVGPAGAVGPRG---PSGPQGIRGDKGEPGEKG-PRGLPGLKGHNGLQGLPGIAGHH 1038 Query: 593 GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLG 650 G G G G GPA + A + G VG AG+ G G G PG G Sbjct: 1039 GDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP 1098 Query: 651 GIPPAAAAKAAKYG 664 G PP + +G Sbjct: 1099 G-PPGVSGGGYDFG 1111 Score = 148 bits (373), Expect = 2e-35 Identities = 203/659 (30%), Positives = 240/659 (36%), Gaps = 111/659 (16%) Query: 54 GALGPGGKPLKPVPGGLAGA------GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 G GP G P P P GL G G G GLG P G + P G AA Sbjct: 57 GPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM----GLMGPRGPPGAA------- 105 Query: 108 AGAGLGGVPGVGGL-GVSAAPSVPGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGAR 164 G PG G G + P PG P G PGK G PG PG PG R Sbjct: 106 ------GAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGK-PGR--PGER 156 Query: 165 FPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGG--PQPGVPLGYPIKA-PKLPGG 221 GV+ P GA P PG+ G F GI G G QPG P +K P PG Sbjct: 157 ----GVVG--PQGARGFPGTPGLPG-FKGIRGHNGLDGLKGQPGAP---GVKGEPGAPGE 206 Query: 222 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG 281 G P TG G+ G G+ G P GP A + G G Sbjct: 207 NGTPGQTGAR-------GLPGERGRVGAP-----GPAGARGSDGSV------GPVGPAGP 248 Query: 282 VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 +G AG PG PGA G I VG A A + G + P GP PG G+ Sbjct: 249 IGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSG---PVGPPGNPGANGL 305 Query: 342 PG----AGVPGVGVPGAGIPVVPG-AGIPG-------AAVPGVVSPEAAAKAAAKAAKYG 389 G AG+PGV AG P +PG GIPG G+V A + ++ G Sbjct: 306 TGAKGAAGLPGV----AGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361 Query: 390 ARPGVGVGGIPTYG-----VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G P G G G G G PG+ G PG G+PG G GV P Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAG-SAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420 Query: 445 EAQAAA-----------AAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG- 492 ++ A+ A + + GL+ G+ G G VGL PG+ PG Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGL-PGIDGRPGP 479 Query: 493 VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVG 551 +G A G IG G K K A GA G G G PG Sbjct: 480 IGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV 539 Query: 552 AGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA-------AVPGVLGGLGALGGVGIPGG 603 G G G PGF +PG A + K G +PG G G G G G Sbjct: 540 QGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGA 599 Query: 604 VVGAGPAAAAAAAKAA---AKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 659 GP + + + G+VGA G G G G+PG G GIP K Sbjct: 600 AGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS-GPSGLPGERGAAGIPGGKGEK 657 Score = 79.0 bits (193), Expect = 1e-14 Identities = 90/289 (31%), Positives = 106/289 (36%), Gaps = 26/289 (8%) Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G G G PG G G G PG P AA+Y GVG+ PG G Sbjct: 39 GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD-GKGVGLGPGPMGLMG 97 Query: 475 VGVAPGVGLAPGVGVAPGVGVAPG----VGVAPGIGPGGVAAAAKS---AAKVAAKAQLR 527 PG APG G PG G A GP G A K + Sbjct: 98 PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERG 157 Query: 528 AAAGLGA----GIPGLG--VGV----GVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA-- 575 GA G PGL G+ G+ GL G PG+ G PG PG A Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217 Query: 576 --AKAAKYGAAVP-GVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 632 + + GA P G G G++G VG G + AGP A + G G AG Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAG 277 Query: 633 LGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 679 G G +G+PG+ G G P P A G A PG +P PG Sbjct: 278 PAG-PRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPG 325 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 155 bits (391), Expect = 2e-37 Identities = 235/761 (30%), Positives = 271/761 (35%), Gaps = 152/761 (19%) Query: 28 GVPGAI-PGGVPGGVFYPG-AGLGALGG--GALGPGGK--------PLKPVPG-GLAGA- 73 G PG + P G+PG +PG G+ G GA GP G P PV GL GA Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422 Query: 74 GLGAGLGAFPAVTFPGALVPGGVADAAAA-----YKAAKAGAGLGGVPGVGGLGVSAAPS 128 G GA PG P G A + + G G PGV G A P Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 129 -------VPGAVVPQPGAGVK-PGKVPG-VGLPGVYPGGVLPGAR-FPGVGVLPGVPTGA 178 + G + P G + P PG VG PG PG R FPG LPG P GA Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG-PKGA 541 Query: 179 ----------GVK--------PKAPGVGGA--FAGIPGV-------GPFGGP----QPGV 207 G K P PG+ GA G PGV GP G P +PG Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601 Query: 208 PLGYPIKAPKLPGGYGLPYTTGKL--PYGYGPGGVAGAAGKAGYPTGTG-VGPQAAAAAA 264 P I+ PG GLP G P G G AG G+ G P G VGP Sbjct: 602 PGSIGIRGQ--PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPP 659 Query: 265 AKAAAKFGAGAAGVL-----------PGVGGA----GVPGVPGAIPGIGGIAGVGTPAAA 309 A + G G PG GG GVPG PGA+ +G G P Sbjct: 660 GLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719 Query: 310 AAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG----- 361 + G A G P GP PG G PG G PG+ G+PG GI PG Sbjct: 720 GEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDR 779 Query: 362 -----------AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI---------- 399 AG GA +PG + P A + + G R VG G Sbjct: 780 GGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGEN 839 Query: 400 -PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYG 458 PT GA GF G G G PGV G PG G G G PG P+ A + G Sbjct: 840 GPT---GAVGFAG-PQGPDGQPGVKGEPGEPGQKGDAGSPG----PQGLAGSPGPHGPNG 891 Query: 459 LVPGVGVAPGVGVAPGVGVAPG-VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 517 VPG+ G PG PG G G A G A +G GP G+ S Sbjct: 892 -VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSH 950 Query: 518 AKVAAKAQLRAAAGLG-------------------AGIPGLGVGVGVPGLGVGAGVPGLG 558 +V + G G AG G VG+PG G+PGL Sbjct: 951 GRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP 1010 Query: 559 VGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKA 618 AG PG GA PG +G G+ G VG PG AG A Sbjct: 1011 GPAGTPGKVGPTGATG-------DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063 Query: 619 AAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 659 + G G AGL G G PG G G P A + Sbjct: 1064 VGERGDRGDPGPAGL----PGSQGAPGTPGPVGAPGDAGQR 1100 Score = 138 bits (347), Expect = 2e-32 Identities = 227/744 (30%), Positives = 260/744 (34%), Gaps = 144/744 (19%) Query: 26 PGGVPGAI--PG-----GVPGGVFYPGA-GL----GALG-------GGALGPGGKPLKPV 66 P G PG + PG G PG +PG+ GL GA G G G G P +P Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564 Query: 67 PGGLAGAGLGAGLGAFPAVTFP-GALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL---- 121 GL GA GL P V P G L P G A G+ G PG GL Sbjct: 565 EPGLPGA---RGLTGNPGVQGPEGKLGPLG-APGEDGRPGPPGSIGIRGQPGSMGLPGPK 620 Query: 122 GVSAAPSVPGAV--VPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR----------FPGVG 169 G S P PG PG PGK VG G L G R F G+ Sbjct: 621 GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680 Query: 170 VLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTT 228 PG P G G KP GV G PG VGP G P G P + + PG GLP Sbjct: 681 GPPG-PPGEGGKPGDQGVPGD----PGAVGPLG---PRGERGNPGERGE-PGITGLPGEK 731 Query: 229 GKLPYGYGPGGVAGAAGKAGYPTGTGV-------GPQAAAAAAAKAAAKFGAGAAGVLPG 281 G + G+GP G G+ G +G P TG G + A + G G G Sbjct: 732 G-MAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGT 790 Query: 282 VGGAGVPGVPGAI--PGIGGIAG----------VGTPAAAAAAAAAAKAAKYGAAAGLVP 329 G G G+PG + PG G G VG P + + + GA P Sbjct: 791 AGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGP 850 Query: 330 GGPGFGPGVVGVPG----------------AGVPGV----GVPGA----GIPVVPGA-GI 364 GP PGV G PG AG PG GVPG G PGA G Sbjct: 851 QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGF 910 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--GIPGV 422 PG+A G V P A A A G G G P G G PG VG G G Sbjct: 911 PGSA--GRVGPPGPAGAPGPAGPLGEP---GKEGPP----GLRGDPGSHGRVGDRGPAGP 961 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLV--PGVGVAPGVGVAPGVGVAPG 480 G PG G PG G PG P+ A + G+V PG G+ PG PG Sbjct: 962 PGGPGDKGDPGEDGQPG----PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPG 1017 Query: 481 ----VGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLR-----AAAG 531 G G VG G GP G A + + A + AG Sbjct: 1018 KVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAG 1077 Query: 532 L--GAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAA-AKAAKYG--- 582 L G PG VG PG G PG G PG +PG +G Sbjct: 1078 LPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRG 1137 Query: 583 -------------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVG 629 +PG G G G GIPG GP + G +G Sbjct: 1138 DRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIG 1197 Query: 630 AAGLGGLGVGGLGVPGVGGLGGIP 653 G+ G VG G G G G P Sbjct: 1198 PPGVRG-SVGEAGPEGPPGEPGPP 1220 Score = 127 bits (318), Expect = 5e-29 Identities = 215/711 (30%), Positives = 247/711 (34%), Gaps = 120/711 (16%) Query: 44 PGAGLGALGGGALGPGGKP-LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAA 102 PG G G G G G+P L PV G+ G AG PG+ P G Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGP--------PGSQGPRGERGPKGR 151 Query: 103 YKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV-PQPGAGVKPGKVPGVGLP--------- 152 + G+ G PGV G AP PG P P +P GL Sbjct: 152 -PGPRGPQGIDGEPGVPGQ--PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208 Query: 153 GVYPGGVLP-GARFPGVGVLPGVPTGAGVK--PKAPGVGGAFAGIPGVGPFGGP------ 203 G+ PG V P G R P L G GAG P PG G I GP G P Sbjct: 209 GLMPGSVGPVGPRGPQG--LQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGED 266 Query: 204 -QPG-------VPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG- 254 +PG V A PG GLP G G G+ G G+ G P G Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR----GHKGLEGPKGEVGAPGSKGE 322 Query: 255 VGPQAAAAAAAKAAAKFGAGAAGVL-----PGVGGA-GVPGVPG-----AIPGIGGIAG- 302 GP A + G G L PG GA G+PG PG IPG G G Sbjct: 323 AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVV------GVPGA----GVPGV-GV 351 G A A G P GP PG+ G PGA G PG G Sbjct: 383 PGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGP 442 Query: 352 PG-AGIPVVPG-------AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--- 399 PG AG P PG GI G PGV + A + +G + +G G Sbjct: 443 PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGK 502 Query: 400 --PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG----VGIS-PEAQAAAAA 452 P G G PG VG G PG G PG G+PG G G VG S P+ Sbjct: 503 RGPRGDPGTVGPPG-PVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561 Query: 453 KAAKYGLVPGVGVAPGVGVAPGVGV-----APGVGLAPGVGVAPGVGVAPGVGVAPG-IG 506 + + GL G+ GV G APG PG + G+ PG PG G Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621 Query: 507 PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGF 566 G A Q R A G G G VG PGL AG G G GF Sbjct: 622 SSGDPGKPGEAGNAGVPGQ-RGAPGKD-GEVGPSGPVGPPGL---AGERGEQGPPGPTGF 676 Query: 567 GAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 626 +PG PG G G G G+PG GP + + G Sbjct: 677 QGLPGP-------------PGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723 Query: 627 LVGAAG----LGGLGVGG-LGVPGVGGLGGI--PPAAAAKAAKYGVAARPG 670 + G G GG G G G PG G G PP + G+A PG Sbjct: 724 ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPG 774 Score = 125 bits (315), Expect = 1e-28 Identities = 202/635 (31%), Positives = 231/635 (36%), Gaps = 66/635 (10%) Query: 23 PSRPG-----GVPG--AIPG-----GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGL 70 P +PG GVPG PG G G V PG G GP G P P G Sbjct: 626 PGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGP 685 Query: 71 AGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVP 130 G G G P PGA+ P G + G+ G+PG G+ P P Sbjct: 686 PGEGGKPGDQGVPGD--PGAVGPLGPR-GERGNPGERGEPGITGLPGEKGMAGGHGPDGP 742 Query: 131 GAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTG--AGVKPK-APGV 187 PG PG GL G +PG R G+ PG P G G+ K A G Sbjct: 743 KG---SPGPSGTPGDTGPPGLQG------MPGER--GIAGTPG-PKGDRGGIGEKGAEGT 790 Query: 188 GG--AFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG 245 G G+PG P G P P P G + P G G P + G P G G GA G Sbjct: 791 AGNDGARGLPG--PLGPPGPAGPTGEKGE-PGPRGLVGPPGSRGN-PGSRGENGPTGAVG 846 Query: 246 KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGV-G 304 AG P G G + K AG+ G G+ G+ P P +PG+ G G G Sbjct: 847 FAG-PQGPD-GQPGVKGEPGEPGQKGDAGSPGP-QGLAGSPGPHGPNGVPGLKGGRGTQG 903 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPG----VGVPG-AGIPV 358 P A +A + G A P GP PG G PG G PG VG G AG P Sbjct: 904 PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963 Query: 359 VPG-AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGV 416 PG G PG PG P A + G G G+P G G PG VG Sbjct: 964 GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLP-GPAGTPG-KVGP 1021 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA--PGVGVAPG 474 G G G PG G PG G G PE A + G V G PG PG Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEP-GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080 Query: 475 VGVAPGVGLAPGVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG 533 APG PG APG G G IGP G A + G Sbjct: 1081 SQGAPGT---PGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRG 1137 Query: 534 -AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG-FG--AVPGALA-AAKAAKYGA----A 584 G G G+ GL G G AG+PG FG PG + + K G Sbjct: 1138 DRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIG 1197 Query: 585 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAA 619 PGV G +G G G PG GP AA Sbjct: 1198 PPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAA 1232 Score = 80.5 bits (197), Expect = 5e-15 Identities = 129/409 (31%), Positives = 145/409 (35%), Gaps = 63/409 (15%) Query: 23 PSRPGGVPGAIPG----GVPGGVFYPGAGLGALGG-------GALGPGGKPLKPVPGGLA 71 P P GVPG G G PG +PG+ G +G G GP G+P K P GL Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATGFPGSA-GRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944 Query: 72 G-AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAG----AGLGGVPGVGGL-GVSA 125 G G +G PG PG D + G AG G G+ G+ G Sbjct: 945 GDPGSHGRVGDRGPAGPPGG--PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002 Query: 126 APSVPGAVVPQPGAGVKPGKVPGVGLPGVY--PGGVLPGARFPGVGVLPGVPTGAGVKPK 183 +PG PG PGKV G G PG V P VG PG P G Sbjct: 1003 ERGMPGL----PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE-PG-PEGPAGNDG 1056 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIK--APKLPGGYGLPYTTGKL--PYGYGPGG 239 PG GA VG G P G P AP PG G P G+ P GP G Sbjct: 1057 TPGRDGA------VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG 1110 Query: 240 VAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGG 299 G AGK G P GPQ + G G G G+ G+PG PG G Sbjct: 1111 PPGRAGKRGLP-----GPQGPRGDKGDHGDRGDRGQKGHR---GFTGLQGLPGP-PGPNG 1161 Query: 300 IAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPV 358 G G P G P GP PGV G G P G PG P Sbjct: 1162 EQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP-EGPPGEPGPP 1220 Query: 359 VPGAGIPG---AAVPGVVS----------PEAAAKAAAKAAKYGARPGV 394 P G PG AA+ ++ PE AA K PGV Sbjct: 1221 GP-PGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGV 1268 Score = 75.9 bits (185), Expect = 1e-13 Identities = 112/359 (31%), Positives = 132/359 (36%), Gaps = 50/359 (13%) Query: 330 GGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKY 388 G FG G G G PG+ +PVV G G PG A P P + + K Sbjct: 103 GNTNFGRGRKGQKGE--PGL------VPVVTGIRGRPGPAGP----PGSQGPRGERGPK- 149 Query: 389 GARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQ 447 RPG P G+ G PGV G PG G PG PG G+S Sbjct: 150 -GRPG----------------PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFS 192 Query: 448 AAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IG 506 A A K GL VG+ PG V P VG GL G A G PG PG +G Sbjct: 193 AQMAGLDEKSGLGSQVGLMPG-SVGP-VGPRGPQGLQGQQGGAGPTG-PPGEPGDPGPMG 249 Query: 507 PGGVAAAAKSAAKVAAKAQLRAAAGLG----AGIPGLGVGVGVPGLGVGAGVPGLGVGAG 562 P G K + G AG PG G PGL PGL G Sbjct: 250 PIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGL------PGLKGHRG 303 Query: 563 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 622 G G + A +K A G +G +G LG G+PG GP A A Sbjct: 304 HKGLEGPKGEVGAP-GSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362 Query: 623 AQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA--AKYGVAARPGFGLSPIFPG 679 + G +G G+ G G G PG+ G G A + + G PG SP PG Sbjct: 363 GKPGPMGPLGIPG-SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG 420 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 153 bits (386), Expect = 6e-37 Identities = 210/699 (30%), Positives = 277/699 (39%), Gaps = 91/699 (13%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 602 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 657 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAV-VPQ-PGAGVK 142 PG+ P G + K GL G PG G G P PG V +P+ PG Sbjct: 658 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGF--- 713 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG----- 189 PG GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 714 PGPRGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLT 770 Query: 190 ------AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 242 +G+PG+ G G P P G +P PG G P T G GP G+ G Sbjct: 771 GHKGFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKG 825 Query: 243 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 +G G P G+ + K + G G + G G+ G+PG PG+ G+ G Sbjct: 826 KSGLPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKG 879 Query: 303 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV----GVPGAGIP 357 G+P A A + + G+ G GF PG+ G+PG +PG G+PG+ Sbjct: 880 SPGSPGVAGLPALSGPKGEKGSV-----GFVGF-PGIPGLPG--IPGTRGLKGIPGSTGK 931 Query: 358 VVPG--AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 + P AG PG PG V + + + G + G G+ GFPG Sbjct: 932 MGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQG-------SAGSNGFPG 984 Query: 412 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGV 471 G G AG PG G+PG G+PG+ + GL PG+ + G+ Sbjct: 985 ----PRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITG 1039 Query: 472 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 531 PG+ PG + G+ +PG+ PG PG+ G + + K Q + Sbjct: 1040 FPGM---PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGF 1092 Query: 532 LGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 590 G G GL +G PG G G+ G+PG PG A + G +PG G Sbjct: 1093 KGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSG 1148 Query: 591 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGL 649 GA+G +G PG + G G G G GV G G+PG G Sbjct: 1149 HQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGE 1208 Query: 650 GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 688 G P K G+ + G P G A L A G Sbjct: 1209 KGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPG 1247 Score = 147 bits (371), Expect = 3e-35 Identities = 230/790 (29%), Positives = 291/790 (36%), Gaps = 168/790 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 182 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 241 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 242 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 297 Query: 115 VPG----VGGLGVSAAPSVPG--AVVPQPG----AGVKPGKVPGVGLPGV-----YPGGV 159 +PG +G GV P G + PG G++ G+ +GLPG G V Sbjct: 298 LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE-GQKGDIGLPGPDVFIDIDGAV 356 Query: 160 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 209 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 357 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 416 Query: 210 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 257 I A LPG GLP GP G G ++G+P G GP Sbjct: 417 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 466 Query: 258 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 302 + K + F A GV P G G PG PG +PG+ G G Sbjct: 467 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 525 Query: 303 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 350 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 526 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 585 Query: 351 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 391 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 586 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 645 Query: 392 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 440 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 646 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 704 Query: 441 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV--------GVAPG 492 PE + K GL PG PG PG+ +PG+ + G APG Sbjct: 705 VHLPELPGFPGPRGEK-GL-PGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPG 762 Query: 493 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 551 G+ G +G G+ V K L G G PG VG PG Sbjct: 763 EQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPGTPGQVGQPGTPGS 817 Query: 552 AGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGAAV----PGVLGGLGALGGVGI 600 +G G+ +G+PG PG K G+ V PG+ G G G VG+ Sbjct: 818 SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 877 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 G G A A + + G VG G+ GL G+PG GL GI P + K Sbjct: 878 KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLP----GIPGTRGLKGI-PGSTGKM 932 Query: 661 AKYGVAARPG 670 G A PG Sbjct: 933 GPSGRAGTPG 942 Score = 140 bits (352), Expect = 5e-33 Identities = 226/769 (29%), Positives = 289/769 (37%), Gaps = 154/769 (20%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 726 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 785 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL--- 121 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 786 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 841 Query: 122 ----GVSAAPSVPGAVVPQPGAGVK--PGKVPGVGL------PGVYPGGVLPGAR----- 164 G PG++V + G+K PG VGL PGV L G + Sbjct: 842 PGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 901 Query: 165 -----FPGVGVLPGVPTGAGVKPKAPGVGGAF-----AGIPGV-------GPFGGPQPGV 207 FPG+ LPG+P G+K PG G AG PG GP G P P Sbjct: 902 VGFVGFPGIPGLPGIPGTRGLKG-IPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRR 960 Query: 208 PLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 266 P+ +K K G G + G P G G AG G G P G+ P + K Sbjct: 961 PMSNLWLKGDK--GSQGSAGSNG-FPGPRGDKGEAGRPGPPGLPGAPGL-PGIIKGVSGK 1016 Query: 267 AAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 324 G G LPG+ G +G+ G PG +PG G G+ G+P A+ G Sbjct: 1017 PGPPGFMGIRG-LPGLKGSSGITGFPG-MPGESGSQGIRGSPGLPGASGLPGLKGDNGQT 1074 Query: 325 AGLV--------PGGPGFGP--------GVVGVPG-------AGVPG-VGVPGA-GIPVV 359 + PG GF G +G PG GV G VG+PGA G P V Sbjct: 1075 VEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV 1134 Query: 360 PGA----GIPGAA----------VPGVVSPEAAAKAAAKAAKYG--------ARPGVGVG 397 G G+PG++ PG++ P+ G PG + Sbjct: 1135 AGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSIT 1194 Query: 398 GIPTYG-----VGAGGFPGFGVGVGGIPGV------AGVPGVGGVPGVGGVPGVGISPEA 446 G+P G G+PG G+G G PG+ G PG+ G G+ G PG+ + P Sbjct: 1195 GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISL-PSL 1253 Query: 447 QAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGI 505 A + GL G PG PG PG G PG PG+ G Sbjct: 1254 IAGQPGDPGRPGL-DGERGRPGPAGPPG---PPGPSSNQGDTGDPGF---PGIPGPKGPK 1306 Query: 506 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 565 G G+ + ++ K +R G G PG VG PG G PG+ AG G Sbjct: 1307 GDQGIPGFSGLPGELGLKG-MRGEPGF-MGTPG---KVGPPG---DPGFPGMKGKAGPRG 1358 Query: 566 FGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 + G A+ PG LG G G G+ G GP + Sbjct: 1359 SSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLP------ 1412 Query: 626 GLVGAAGLGGL--GVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 670 G+ G G GL G LG PG+ GL G P A + +G+ PG Sbjct: 1413 GIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1461 Score = 127 bits (319), Expect = 3e-29 Identities = 206/714 (28%), Positives = 258/714 (36%), Gaps = 139/714 (19%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K G Sbjct: 50 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYG----------PKGDKGPM 97 Query: 114 GVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 171 GVPG LG++ P PG P+ PG G VG PG P G +PG+ Sbjct: 98 GVPGF--LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGP 147 Query: 172 PGVPTGAGVKPKAPGVGGAF------AGIPGVGPFGGPQ--PGVPLGY-PIKAPKLPGGY 222 PG+P G K G+F G+PG+ GPQ PG P P P L G Sbjct: 148 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 207 Query: 223 GLP---YTTGKLPYGY----GPGGVAGAAGKAGYPTGTG----VG-PQAAAAAAAKAAAK 270 G P G + G+ G G G G AG P TG +G P+ + + K Sbjct: 208 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 267 Query: 271 FGAGAAGV--LPGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA 325 G +G PG+G G G G IPG+ G G +G+ K G Sbjct: 268 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG--- 324 Query: 326 GLVPGGPGFGPGVVGVPG-AGVPG----VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAAA 379 PG GF G+ G G G+PG + + GA I PG G+PG +PG+ E Sbjct: 325 --FPGLNGF-QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG--LPGLKGDEGI- 378 Query: 380 KAAAKAAKYGARPGVGVGGIPTY-----GVGAGGFPGF----------GVGVGGIPGVAG 424 G R GV G+P +G GFPG +G G+PG G Sbjct: 379 --------QGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 430 Query: 425 VPGVGGVPG--------------VGGVPGVGISPEAQAAAAAKAAK--------YGLVPG 462 +PG G PG G PG+ + K K G VP Sbjct: 431 LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 490 Query: 463 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGP-GGVAAAAKSAAKV 520 G PG PG G+ G G G A G APG +GP G K + Sbjct: 491 TG-PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPI 549 Query: 521 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 580 + Q G+PG G G G PG G+PG +PG + Sbjct: 550 LSTIQ---------GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGE 600 Query: 581 YGAAVPGVLGGLGALGGVGIPG-GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL----- 633 G +PG+ G G G G+PG G+ G GP Q GL G+ G+ Sbjct: 601 KG--LPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCI 658 Query: 634 --GGLGVGGL----GVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 679 G G G G PG G G+P P + G PG P PG Sbjct: 659 IPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPG 712 Score = 92.8 bits (229), Expect = 9e-19 Identities = 155/530 (29%), Positives = 195/530 (36%), Gaps = 89/530 (16%) Query: 198 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 251 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 53 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 110 Query: 252 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 307 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 111 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 161 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 364 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 162 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 206 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 422 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 207 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 263 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 482 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 264 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 317 Query: 483 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 318 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 373 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 374 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 431 Query: 601 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL---------------- 641 PG GP + + K + F GL G G G LG+ G+ Sbjct: 432 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 491 Query: 642 ------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFGLSPIFPGG 680 G PG GL G+P A+ + G A PG + P+ P G Sbjct: 492 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 540 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 153 bits (386), Expect = 6e-37 Identities = 210/699 (30%), Positives = 277/699 (39%), Gaps = 91/699 (13%) Query: 28 GVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 G+PG +PG G PG PG GL L G PG K +PG GL G Sbjct: 601 GLPG-LPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQ---QGLPGSKGITLPC 656 Query: 86 TFPGALVPGGVADAAAAYKAAKAGAGLGGVPGV-GGLGVSAAPSVPGAV-VPQ-PGAGVK 142 PG+ P G + K GL G PG G G P PG V +P+ PG Sbjct: 657 IIPGSYGPSGFP-GTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGF--- 712 Query: 143 PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVP-----TGA--GVKPKAPGVGG----- 189 PG GLPG +PG LPG PG+ PG+P TG G + APG G Sbjct: 713 PGPRGEKGLPG-FPG--LPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLT 769 Query: 190 ------AFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 242 +G+PG+ G G P P G +P PG G P T G GP G+ G Sbjct: 770 GHKGFLGDSGLPGLKGVHGKPGLLGPKGER-GSPGTPGQVGQPGTPGSS----GPYGIKG 824 Query: 243 AAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG 302 +G G P G+ + K + G G + G G+ G+PG PG+ G+ G Sbjct: 825 KSGLPGAPGFPGI-----SGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGN-PGLVGLKG 878 Query: 303 V-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV----GVPGAGIP 357 G+P A A + + G+ G GF PG+ G+PG +PG G+PG+ Sbjct: 879 SPGSPGVAGLPALSGPKGEKGSV-----GFVGF-PGIPGLPG--IPGTRGLKGIPGSTGK 930 Query: 358 VVPG--AGIPGA----AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 + P AG PG PG V + + + G + G G+ GFPG Sbjct: 931 MGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQG-------SAGSNGFPG 983 Query: 412 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGV 471 G G AG PG G+PG G+PG+ + GL PG+ + G+ Sbjct: 984 ----PRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGL-PGLKGSSGITG 1038 Query: 472 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG 531 PG+ PG + G+ +PG+ PG PG+ G + + K Q + Sbjct: 1039 FPGM---PGESGSQGIRGSPGL---PGASGLPGL-KGDNGQTVEISGSPGPKGQPGESGF 1091 Query: 532 LGA-GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLG 590 G G GL +G PG G G+ G+PG PG A + G +PG G Sbjct: 1092 KGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV--AGMRGEPG--LPGSSG 1147 Query: 591 GLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG-LGVPGVGGL 649 GA+G +G PG + G G G G GV G G+PG G Sbjct: 1148 HQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGE 1207 Query: 650 GGIPPAAAAKAAKYGVAARPGFGLSPIFPGGACLGKACG 688 G P K G+ + G P G A L A G Sbjct: 1208 KGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPG 1246 Score = 147 bits (371), Expect = 3e-35 Identities = 230/790 (29%), Positives = 291/790 (36%), Gaps = 168/790 (21%) Query: 20 ILHPSRPGGVPGAI-PGGVPGGVFYPG----------AGLGALGG-------GALGPGGK 61 I P G PGA+ P G PG PG GLG G G GP G Sbjct: 181 ITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGP 240 Query: 62 P-------LKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGG 114 P P G G+ G FP ++ P PG K K G+ G Sbjct: 241 PPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGP----PGFPGLGTTGEKGEKGEKGIPG 296 Query: 115 VPG----VGGLGVSAAPSVPG--AVVPQPG----AGVKPGKVPGVGLPGV-----YPGGV 159 +PG +G GV P G + PG G++ G+ +GLPG G V Sbjct: 297 LPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIE-GQKGDIGLPGPDVFIDIDGAV 355 Query: 160 LPG-ARFPGVGVLPGVPTGAGVKP-KAP-GVGG--AFAGIPG-VGPFGGP----QPGVPL 209 + G PGV LPG+ G++ + P GV G A +G+PG +GP G P G P Sbjct: 356 ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 415 Query: 210 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAG-----------KAGYPTGTG-VGP 257 I A LPG GLP GP G G ++G+P G GP Sbjct: 416 RTTIGAAGLPGRDGLP----------GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGP 465 Query: 258 QA-AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG--------- 302 + K + F A GV P G G PG PG +PG+ G G Sbjct: 466 KGNLGLKGIKGDSGFCACDGGV-PNTGPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQG 524 Query: 303 -VGTPAAAAAAAAAAKAAKYG-AAAGLVPGGPGFG--------PGVVGVPGA-GVPGV-G 350 G P + K G + G PG GV+G PG GVPG+ G Sbjct: 525 PAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPG 584 Query: 351 VPG------------AGIPVVPG-------AGIPGAAVPGVVSPEAAAKAAAKAAKYGAR 391 +PG G+P +PG G+PG +PG+ P K G + Sbjct: 585 LPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQ 644 Query: 392 PGVGVGGI-----------PTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV 440 G GI P+ G GFPG G G+PG G PG G G G PG+ Sbjct: 645 GLPGSKGITLPCIIPGSYGPSGFPGTPGFPG-PKGSRGLPGTPGQPGSSGSKGEPGSPGL 703 Query: 441 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGV--------GVAPG 492 PE + K GL PG PG PG+ +PG+ + G APG Sbjct: 704 VHLPELPGFPGPRGEK-GL-PGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPG 761 Query: 493 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVG 551 G+ G +G G+ V K L G G PG VG PG Sbjct: 762 EQGLQGLTGHKGFLGDSGL----PGLKGVHGKPGLLGPKG-ERGSPGTPGQVGQPGTPGS 816 Query: 552 AGVPGLGVGAGVPGFGAVPGAL-------AAAKAAKYGAAV----PGVLGGLGALGGVGI 600 +G G+ +G+PG PG K G+ V PG+ G G G VG+ Sbjct: 817 SGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGL 876 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 G G A A + + G VG G+ GL G+PG GL GI P + K Sbjct: 877 KGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLP----GIPGTRGLKGI-PGSTGKM 931 Query: 661 AKYGVAARPG 670 G A PG Sbjct: 932 GPSGRAGTPG 941 Score = 140 bits (352), Expect = 5e-33 Identities = 226/769 (29%), Positives = 289/769 (37%), Gaps = 154/769 (20%) Query: 23 PSRPG--GVPGAI-----PG--GVPGGVF-----YPGA-GLGALGG--GALGPGGKP-LK 64 P PG G+PG I PG G G +F PG GL L G G LG G P LK Sbjct: 725 PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLK 784 Query: 65 PVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL--- 121 V G GL G + PG + G ++ Y K +GL G PG G+ Sbjct: 785 GVHGK---PGLLGPKGERGSPGTPGQVGQPGTPGSSGPY-GIKGKSGLPGAPGFPGISGH 840 Query: 122 ----GVSAAPSVPGAVVPQPGAGVK--PGKVPGVGL------PGVYPGGVLPGAR----- 164 G PG++V + G+K PG VGL PGV L G + Sbjct: 841 PGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGS 900 Query: 165 -----FPGVGVLPGVPTGAGVKPKAPGVGGAF-----AGIPGV-------GPFGGPQPGV 207 FPG+ LPG+P G+K PG G AG PG GP G P P Sbjct: 901 VGFVGFPGIPGLPGIPGTRGLKG-IPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRR 959 Query: 208 PLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAK 266 P+ +K K G G + G P G G AG G G P G+ P + K Sbjct: 960 PMSNLWLKGDK--GSQGSAGSNG-FPGPRGDKGEAGRPGPPGLPGAPGL-PGIIKGVSGK 1015 Query: 267 AAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAA 324 G G LPG+ G +G+ G PG +PG G G+ G+P A+ G Sbjct: 1016 PGPPGFMGIRG-LPGLKGSSGITGFPG-MPGESGSQGIRGSPGLPGASGLPGLKGDNGQT 1073 Query: 325 AGLV--------PGGPGFGP--------GVVGVPG-------AGVPG-VGVPGA-GIPVV 359 + PG GF G +G PG GV G VG+PGA G P V Sbjct: 1074 VEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGV 1133 Query: 360 PGA----GIPGAA----------VPGVVSPEAAAKAAAKAAKYG--------ARPGVGVG 397 G G+PG++ PG++ P+ G PG + Sbjct: 1134 AGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSIT 1193 Query: 398 GIPTYG-----VGAGGFPGFGVGVGGIPGV------AGVPGVGGVPGVGGVPGVGISPEA 446 G+P G G+PG G+G G PG+ G PG+ G G+ G PG+ + P Sbjct: 1194 GVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISL-PSL 1252 Query: 447 QAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGI 505 A + GL G PG PG PG G PG PG+ G Sbjct: 1253 IAGQPGDPGRPGL-DGERGRPGPAGPPG---PPGPSSNQGDTGDPGF---PGIPGPKGPK 1305 Query: 506 GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPG 565 G G+ + ++ K +R G G PG VG PG G PG+ AG G Sbjct: 1306 GDQGIPGFSGLPGELGLKG-MRGEPGF-MGTPG---KVGPPG---DPGFPGMKGKAGPRG 1357 Query: 566 FGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 + G A+ PG LG G G G+ G GP + Sbjct: 1358 SSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLP------ 1411 Query: 626 GLVGAAGLGGL--GVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 670 G+ G G GL G LG PG+ GL G P A + +G+ PG Sbjct: 1412 GIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPG 1460 Score = 127 bits (319), Expect = 3e-29 Identities = 206/714 (28%), Positives = 258/714 (36%), Gaps = 139/714 (19%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLG 113 G GP G P G G+ +GL FPG L P G K G Sbjct: 49 GRPGPIGIQGPTGPQGFTGSTGLSGLKGERG--FPGLLGPYG----------PKGDKGPM 96 Query: 114 GVPGVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVL 171 GVPG LG++ P PG P+ PG G VG PG P G +PG+ Sbjct: 97 GVPGF--LGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPG--PDG------YPGLLGP 146 Query: 172 PGVPTGAGVKPKAPGVGGAF------AGIPGVGPFGGPQ--PGVPLGY-PIKAPKLPGGY 222 PG+P G K G+F G+PG+ GPQ PG P P P L G Sbjct: 147 PGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP 206 Query: 223 GLP---YTTGKLPYGY----GPGGVAGAAGKAGYPTGTG----VG-PQAAAAAAAKAAAK 270 G P G + G+ G G G G AG P TG +G P+ + + K Sbjct: 207 GPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPK 266 Query: 271 FGAGAAGV--LPGVGGAGVPGVPG--AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA 325 G +G PG+G G G G IPG+ G G +G+ K G Sbjct: 267 GFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG--- 323 Query: 326 GLVPGGPGFGPGVVGVPG-AGVPG----VGVPGAGIPVVPG-AGIPGAAVPGVVSPEAAA 379 PG GF G+ G G G+PG + + GA I PG G+PG +PG+ E Sbjct: 324 --FPGLNGF-QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPG--LPGLKGDEGI- 377 Query: 380 KAAAKAAKYGARPGVGVGGIPTY-----GVGAGGFPGF----------GVGVGGIPGVAG 424 G R GV G+P +G GFPG +G G+PG G Sbjct: 378 --------QGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDG 429 Query: 425 VPGVGGVPG--------------VGGVPGVGISPEAQAAAAAKAAK--------YGLVPG 462 +PG G PG G PG+ + K K G VP Sbjct: 430 LPGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPN 489 Query: 463 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG-IGP-GGVAAAAKSAAKV 520 G PG PG G+ G G G A G APG +GP G K + Sbjct: 490 TG-PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPI 548 Query: 521 AAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAK 580 + Q G+PG G G G PG G+PG +PG + Sbjct: 549 LSTIQ---------GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGE 599 Query: 581 YGAAVPGVLGGLGALGGVGIPG-GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGL----- 633 G +PG+ G G G G+PG G+ G GP Q GL G+ G+ Sbjct: 600 KG--LPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCI 657 Query: 634 --GGLGVGGL----GVPGVGGLGGIP--PAAAAKAAKYGVAARPGFGLSPIFPG 679 G G G G PG G G+P P + G PG P PG Sbjct: 658 IPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPG 711 Score = 92.8 bits (229), Expect = 9e-19 Identities = 155/530 (29%), Positives = 195/530 (36%), Gaps = 89/530 (16%) Query: 198 GPFGGPQPGVPLGYPIKA--PKLPGGYGLPYTTGKLPYG----YGPGGVAGAAGKAGYPT 251 GP G P P G+ L G G P G PYG GP GV G G G P Sbjct: 52 GPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLG--PYGPKGDKGPMGVPGFLGINGIPG 109 Query: 252 GTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI--PGIGGIAGV-GTPA 307 G GP+ G G VG G G PG + PG+ G G G P Sbjct: 110 HPGQPGPRGPPGLD---------GCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPV 160 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGA--GI 364 A + K G PG PG+ G+ G G PG PGA P P G Sbjct: 161 LAPGSFKGMK------------GDPGL-PGLDGITGPQGAPGF--PGAVGPAGPPGLQGP 205 Query: 365 PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPGV 422 PG PG + P+ + K G + VG+ G P G F GF G G G Sbjct: 206 PGP--PGPLGPDGNMGLGFQGEK-GVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGE 262 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 482 G G G+ G G PG+G + E + + G +PG+ G + GV PG Sbjct: 263 PGPKGFPGISGPPGFPGLGTTGEK-----GEKGEKG-IPGLPGPRGPMGSEGVQGPPGQQ 316 Query: 483 LAPGVGVAPGVGVAPGV-GVAPGIG-PGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLG 540 G PG+ G+ G IG PG A ++ GL PGL Sbjct: 317 GKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGL----PGLK 372 Query: 541 VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGI 600 G+ GL +GVPGL +GVPG P K + G +G G G G+ Sbjct: 373 GDEGIQGLRGPSGVPGLPALSGVPG-ALGPQGFPGLKGDQ-GNPGRTTIGAAGLPGRDGL 430 Query: 601 PGGVVGAGPAAAAAAAKAA-AKAAQF-GLVGAAG-LGGLGVGGL---------------- 641 PG GP + + K + F GL G G G LG+ G+ Sbjct: 431 PGPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNT 490 Query: 642 ------GVPGVGGLGGIPPAAAAKAAK-----YGVAARPGFGLSPIFPGG 680 G PG GL G+P A+ + G A PG + P+ P G Sbjct: 491 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGL-VGPLGPSG 539 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 149 bits (376), Expect = 8e-36 Identities = 203/647 (31%), Positives = 235/647 (36%), Gaps = 160/647 (24%) Query: 52 GGGALGPGG----KPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAK 107 GGGA G G K ++P+ G G G G + + P L+P Sbjct: 29 GGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLP--LLP-------------- 72 Query: 108 AGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVY----PGGVLPGA 163 L G PG P PG P PG PGK PG+G PG++ P G PG Sbjct: 73 --MDLKGEPG--------PPGKPGPRGP-PGPPGFPGK-PGMGKPGLHGQPGPAGP-PGF 119 Query: 164 RFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQ--PGVPLGYPIKAPKLPGG 221 G PG+P G P PG+ G GI G GP PG+P I P PG Sbjct: 120 SRMGKAGPPGLPGKVG-PPGQPGLRGE-PGIRGDQGLRGPPGPPGLPGPSGITIPGKPGA 177 Query: 222 YGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPG 281 G+P GP G G G G P GP G G G LPG Sbjct: 178 QGVP----------GPPGFQGEPGPQGEP-----GPPGDRGLKGDN----GVGQPG-LPG 217 Query: 282 VGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G G G PG PG+ G AG+G P A + G VPG G PG VG Sbjct: 218 APGQG--GAPGP-PGLPGPAGLGKPGLDGLPGAPGDKGESGPPG--VPGPRG-EPGAVGP 271 Query: 342 PGA-GVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP 400 G GV GVGVPGA AG+PG P GA+ G G P Sbjct: 272 KGPPGVDGVGVPGA-------AGLPGPQGPS-----------------GAKGEPGTRGPP 307 Query: 401 TYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGV---GGVPGVGISPEAQAAAAAKAAKY 457 +G G+ G+ G+PG G G GVPG+ G PG P Q Sbjct: 308 GL-IGPTGY-----GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQ------- 354 Query: 458 GLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKS 516 G+G PG+ PG PG PG G G PGV G+ GP G+A Sbjct: 355 ----GLGGPPGL---PGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLA----- 402 Query: 517 AAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA 576 G PG+ G+PG G PG G PGF PG Sbjct: 403 ------------------GKPGVPGERGLPG---AHGPPGPTGPKGEPGFTGRPGG---- 437 Query: 577 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 636 PGV G LG G +G+PG GP+ A GL G G GL Sbjct: 438 ---------PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGL 488 Query: 637 ----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G G G PG G G PP G PG P PG Sbjct: 489 PGPPGEGRAGEPGTAGPTG-PPGVPGSPGITGPPGPPGPPGPPGAPG 534 Score = 137 bits (344), Expect = 4e-32 Identities = 173/533 (32%), Positives = 212/533 (39%), Gaps = 56/533 (10%) Query: 15 LLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA-GLGALG-GGALGPGGKPLKPVPGGLAG 72 LL + + P G PG P G PG +PG G+G G G GP G P G Sbjct: 70 LLPMDLKGEPGPPGKPG--PRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGP 127 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGA 132 GL +G G PG D + + G G+PG G+ + P G Sbjct: 128 PGLPGKVGPPGQPGLRGE--PGIRGD-----QGLRGPPGPPGLPGPSGITIPGKPGAQGV 180 Query: 133 VVP-----QPGAGVKPGKVPGVGLPGVYPGGV--LPGARFPGVGVLPG---VPTGAGV-K 181 P +PG +PG GL G G LPGA PG G PG +P AG+ K Sbjct: 181 PGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGA--PGQGGAPGPPGLPGPAGLGK 238 Query: 182 PKAPGVGGAFAGIPGVGPFGGPQP-GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGV 240 P G+ GA GP G P P G P K P G G+P G LP GP G Sbjct: 239 PGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAG-LPGPQGPSGA 297 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGI 300 G G G P G +GP K G AGV +G G PG G PG G Sbjct: 298 KGEPGTRG-PPGL-IGPTGYGMPGLPGP-KGDRGPAGVPGLLGDRGEPGEDGE-PGEQGP 353 Query: 301 AGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVP 360 G+G P +A + G GPG PGV G+ G P G+ AG P VP Sbjct: 354 QGLGGPPGLPGSAGLP--GRRGPPGPKGEAGPGGPPGVPGIRGDQGPS-GL--AGKPGVP 408 Query: 361 GA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFG--VGV 416 G G+PGA PG P+ + G +G G +G G PG G+ Sbjct: 409 GERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKG----DLGLPGQPGLRGPSGI 464 Query: 417 GGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 475 G+ G AG G G+PG+ G PG+ G E +A A G PGV +PG+ PG Sbjct: 465 PGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTG-PPGVPGSPGITGPPGP 523 Query: 476 GVAPGVGLAPGVGVAPGV-----------GVAPGVGVAPGIGPGGVAAAAKSA 517 PG APG G+ G G G P G G ++A A A Sbjct: 524 PGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATPA 576 Score = 65.9 bits (159), Expect = 1e-10 Identities = 93/283 (32%), Positives = 112/283 (39%), Gaps = 37/283 (13%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVT 86 G+PG +PG P G P G LG G G G+P + P GL G G P Sbjct: 316 GMPG-LPG--PKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRR 372 Query: 87 FP----GALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGA 139 P G PGG + + +GL G PGV G G+ A PG P +PG Sbjct: 373 GPPGPKGEAGPGG-PPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGF 431 Query: 140 GVKPGKVPGV-------------GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 186 +PG PGV G PG+ +PG + P + P G +P PG Sbjct: 432 TGRPGG-PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPG 490 Query: 187 VGG-AFAGIPGV-GPFGGP----QPGV--PLGYPIKAPKLPGGYGLPYTTGKLPYGYGPG 238 G AG PG GP G P PG+ P G P P PG G TG G Sbjct: 491 PPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPP-GPPGPPGAPGAFDETGIAGLHLPNG 549 Query: 239 GVAGAA-GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 280 GV GA GK G P G+G +A A A A A +P Sbjct: 550 GVEGAVLGKGGKPQ-FGLGELSAHATPAFTAVLTSPFPASGMP 591 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 149 bits (375), Expect = 1e-35 Identities = 165/503 (32%), Positives = 199/503 (39%), Gaps = 79/503 (15%) Query: 136 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 190 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 246 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 306 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 363 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 421 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 422 VAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 479 G PG+GG PG G+PG+ + P + G+V G PG PG+ P Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG-PPGPKGEPGLQGFP 437 Query: 480 GVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG----A 534 G G PG+ PG +G G GV + K + G Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497 Query: 535 GIPGLG---VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 591 GIPG+G +G PG+ G PGL G PG G PG A +G PG G Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKPGA 549 Query: 592 LGALGGVGIPGGVVGAGPAAAAA 614 LG G G+PG GP A Sbjct: 550 LGPQGQPGLPGPPGPPGPPGPPA 572 Score = 137 bits (344), Expect = 4e-32 Identities = 175/515 (33%), Positives = 214/515 (41%), Gaps = 81/515 (15%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGV-GGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV-GLPGVY--PGGV-LPGARFPGVGV 170 PG G G P G P+ G PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 171 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 227 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 228 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 283 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 284 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGFGPG 337 G G PG+PG IPG G G +G P G GL PG PGF G Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF-LG 444 Query: 338 VVGVPGA-GVPG-VGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 394 VG PG G+PG +G G AG VPG +PG VPG++ P+ G PG+ Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPG--LPG--VPGLLGPKGEPGIPGDQGLQGP-PGI 499 Query: 395 -GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG-----------------------G 430 G+GG P+ +G G PG G G+PG G PG+G G Sbjct: 500 PGIGG-PSGPIGPPGIPG-PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 465 +PG G PG P +Y G+G+ Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Score = 134 bits (336), Expect = 4e-31 Identities = 179/557 (32%), Positives = 211/557 (37%), Gaps = 119/557 (21%) Query: 123 VSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 182 + AP + VP+ G ++P L G PG R P P Sbjct: 93 IQPAPRMGKEAVPKKGK-----EIPLASLRGEQGPRGEPGPRGP---------------P 132 Query: 183 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVA 241 PG+ G GIPG+ GPQ GYP + P +PG G P G +P G G Sbjct: 133 GPPGLPGH--GIPGIKGKPGPQ-----GYPGVGKPGMPGMPGKPGAMG-MPGAKGEIGQK 184 Query: 242 GAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIA 301 G G G P GPQ G LPG+G G PG+PG PG G Sbjct: 185 GEIGPMGIP-----GPQ-------------GPPGPHGLPGIGKPGGPGLPGQ-PGPKGDR 225 Query: 302 GV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGV-GVPGAGIP 357 G G P A V G PG PG VG+PG G PGV G PG P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 285 Query: 358 VVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGV---GGIPTYGVGAGGFPGFG- 413 + G PGA PG P+ G PG+G GIP G GFPG Sbjct: 286 L----GKPGA--PGEPGPQGPIGVPGVQGPPGI-PGIGKPGQDGIP----GQPGFPGGKG 334 Query: 414 -VGVGGIPGVAGVPGVG--GVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVG 470 G+ G+PG G+PG+G G PG G G+G P A K +G APG+G Sbjct: 335 EQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGP-------IG-APGIG 386 Query: 471 VAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 PG PG+ PG PG PG GI GP G + Sbjct: 387 GPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGGIVGPQGPPGP-------------KGE 430 Query: 530 AGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA-------GVPGFGAVPGALAAAKAAK 580 GL G PG VG PG+ G+PG +G GVPG VPG L Sbjct: 431 PGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGPKGEAGQKGVPGLPGVPGLLGPK---- 482 Query: 581 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 640 PG+ G G G GIPG +GP + G G G+G GV G Sbjct: 483 ---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539 Query: 641 L----GVPGVGGLGGIP 653 L G PG G G P Sbjct: 540 LHGPPGKPGALGPQGQP 556 Score = 124 bits (310), Expect = 4e-28 Identities = 163/540 (30%), Positives = 198/540 (36%), Gaps = 109/540 (20%) Query: 179 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 232 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 348 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 464 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 465 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 524 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 525 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 583 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 584 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 624 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 625 FGLVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G VG G+ GL G G GV GL G+P K + G+ G P PG Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPK-GEPGIPGDQGLQGPPGIPG 501 Score = 110 bits (276), Expect = 3e-24 Identities = 139/415 (33%), Positives = 164/415 (39%), Gaps = 76/415 (18%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G P + PG +PG + K GL G+PG GL P PG Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG--- 357 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 194 P+ G+ G VPG P G + GA PG+G PG P G+ P G GA G Sbjct: 358 PKGDRGM--GGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GF 409 Query: 195 PG-------VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 244 PG VGP G P P G P G+P K P G G P G LP GP G AG Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQK 467 Query: 245 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIG 298 G G P G+ GP+ + G G+ G G PG+PG +PG Sbjct: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G+G P A K PG GP PG+ G PG PG P A + Sbjct: 528 GFPGIGKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVM 574 Query: 357 PVVP---GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 P P G +P G + GV P A YGA+ G G P Y + A Sbjct: 575 PPTPPPQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 149 bits (375), Expect = 1e-35 Identities = 165/503 (32%), Positives = 199/503 (39%), Gaps = 79/503 (15%) Query: 136 QPGAGVKPGK--VPGVGLPGVY----PGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 +PG PG +PG G+PG+ P G PG PG+ +PG P G+ PG G Sbjct: 125 EPGPRGPPGPPGLPGHGIPGIKGKPGPQGY-PGVGKPGMPGMPGKPGAMGM----PGAKG 179 Query: 190 AFAGIPGVGPFGGPQPGVPLGYPIKAPKL--PGGYGLPYTTGKLPYG-YGPGGVAGAAGK 246 +GP G P P P G P P + PGG GLP G P G GP G+ G G Sbjct: 180 EIGQKGEIGPMGIPGPQGPPG-PHGLPGIGKPGGPGLPGQPG--PKGDRGPKGLPGPQGL 236 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTP 306 G G G A PGV G PG+ G PG G+ GVG P Sbjct: 237 RGPKGDKGFGMPGA-------------------PGVKGP--PGMHGP-PGPVGLPGVGKP 274 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGA-GIPVVPG--AG 363 K GA P GP PGV G P G+PG+G PG GIP PG G Sbjct: 275 GVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPP--GIPGIGKPGQDGIPGQPGFPGG 332 Query: 364 IPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGI--PTYGVGAGGFPGFGVGVGGIPG 421 +PG+ P PG+G G P G GG PG +G G G Sbjct: 333 KGEQGLPGLPGPPGL-------------PGIGKPGFPGPKGDRGMGGVPG-ALGPRGEKG 378 Query: 422 VAGVPGVGGVPGVGGVPGV--GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 479 G PG+GG PG G+PG+ + P + G+V G PG PG+ P Sbjct: 379 PIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQG-PPGPKGEPGLQGFP 437 Query: 480 GVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG----A 534 G G PG+ PG +G G GV + K + G Sbjct: 438 GKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPP 497 Query: 535 GIPGLG---VGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 591 GIPG+G +G PG+ G PGL G PG G PG A +G PG G Sbjct: 498 GIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK-PGV-----AGLHGP--PGKPGA 549 Query: 592 LGALGGVGIPGGVVGAGPAAAAA 614 LG G G+PG GP A Sbjct: 550 LGPQGQPGLPGPPGPPGPPGPPA 572 Score = 137 bits (344), Expect = 4e-32 Identities = 175/515 (33%), Positives = 214/515 (41%), Gaps = 81/515 (15%) Query: 7 AAPRPGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG----------GAL 56 A P+ G + L S+ P G PG P G PG PG G+ + G G Sbjct: 103 AVPKKGKEIPLASLRGEQGPRGEPG--PRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 57 GPGGKPLKPVPGGLAGAGLGAGL-GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV 115 G G P KP G+ GA G G + PG P G K G GL G Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPG--GPGLPGQ 218 Query: 116 PGV-GGLGVSAAPSVPGAVVPQPGAGVKPGKVPGV-GLPGVY--PGGV-LPGARFPGVGV 170 PG G G P G P+ G PGV G PG++ PG V LPG PGV Sbjct: 219 PGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTG 278 Query: 171 LPGVPTGAGVKPKAPGVGGAFA--GIPGVGPFGGPQPGVP-LGYPIKAPKLPGGYGLPYT 227 PG P G KP APG G G+PGV GP PG+P +G P + +PG G P Sbjct: 279 FPG-PQGPLGKPGAPGEPGPQGPIGVPGVQ---GP-PGIPGIGKPGQ-DGIPGQPGFPGG 332 Query: 228 TGK--LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVL--PGVG 283 G+ LP GP G+ G GK G+P GP+ A G G + PG+G Sbjct: 333 KGEQGLPGLPGPPGLPGI-GKPGFP-----GPKGDRGMGGVPGALGPRGEKGPIGAPGIG 386 Query: 284 GA-GVPGVPGAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--GL--VPGGPGFGPG 337 G G PG+PG IPG G G +G P G GL PG PGF G Sbjct: 387 GPPGEPGLPG-IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF-LG 444 Query: 338 VVGVPGA-GVPG-VGVPG-AGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGV 394 VG PG G+PG +G G AG VPG +PG VPG++ P+ G PG+ Sbjct: 445 EVGPPGMRGLPGPIGPKGEAGQKGVPG--LPG--VPGLLGPKGEPGIPGDQGLQGP-PGI 499 Query: 395 -GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG-----------------------G 430 G+GG P+ +G G PG G G+PG G PG+G G Sbjct: 500 PGIGG-PSGPIGPPGIPG-PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPG 557 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 465 +PG G PG P +Y G+G+ Sbjct: 558 LPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGI 592 Score = 134 bits (336), Expect = 4e-31 Identities = 179/557 (32%), Positives = 211/557 (37%), Gaps = 119/557 (21%) Query: 123 VSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKP 182 + AP + VP+ G ++P L G PG R P P Sbjct: 93 IQPAPRMGKEAVPKKGK-----EIPLASLRGEQGPRGEPGPRGP---------------P 132 Query: 183 KAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPKLPGGYGLPYTTGKLPYGYGPGGVA 241 PG+ G GIPG+ GPQ GYP + P +PG G P G +P G G Sbjct: 133 GPPGLPGH--GIPGIKGKPGPQ-----GYPGVGKPGMPGMPGKPGAMG-MPGAKGEIGQK 184 Query: 242 GAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIA 301 G G G P GPQ G LPG+G G PG+PG PG G Sbjct: 185 GEIGPMGIP-----GPQ-------------GPPGPHGLPGIGKPGGPGLPGQ-PGPKGDR 225 Query: 302 GV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG--PGVVGVPGAGVPGV-GVPGAGIP 357 G G P A V G PG PG VG+PG G PGV G PG P Sbjct: 226 GPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGP 285 Query: 358 VVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGV---GGIPTYGVGAGGFPGFG- 413 + G PGA PG P+ G PG+G GIP G GFPG Sbjct: 286 L----GKPGA--PGEPGPQGPIGVPGVQGPPGI-PGIGKPGQDGIP----GQPGFPGGKG 334 Query: 414 -VGVGGIPGVAGVPGVG--GVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVG 470 G+ G+PG G+PG+G G PG G G+G P A K +G APG+G Sbjct: 335 EQGLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGP-------IG-APGIG 386 Query: 471 VAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAA 529 PG PG+ PG PG PG GI GP G + Sbjct: 387 GPPGEPGLPGI---PGPMGPPGAIGFPGPKGEGGIVGPQGPPGP-------------KGE 430 Query: 530 AGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGA-------GVPGFGAVPGALAAAKAAK 580 GL G PG VG PG+ G+PG +G GVPG VPG L Sbjct: 431 PGLQGFPGKPGFLGEVGPPGM---RGLPG-PIGPKGEAGQKGVPGLPGVPGLLGPK---- 482 Query: 581 YGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 640 PG+ G G G GIPG +GP + G G G+G GV G Sbjct: 483 ---GEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539 Query: 641 L----GVPGVGGLGGIP 653 L G PG G G P Sbjct: 540 LHGPPGKPGALGPQGQP 556 Score = 124 bits (310), Expect = 4e-28 Identities = 163/540 (30%), Positives = 198/540 (36%), Gaps = 109/540 (20%) Query: 179 GVKPKAPGVGGAFAG-IPGVGPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLP 232 G+KP P + IP P G P +PL A P L G P+ LP Sbjct: 32 GIKPLPPQIPPQMPPQIPQYQPLGQQVPHMPLAKDGLAMGKEMPHLQYGKEYPH----LP 87 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 A GK P P A+ + G PG+ G G+PG+ G Sbjct: 88 QYMKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKG 147 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPG 348 PG G GVG P +PG PG PG +G+PGA G G Sbjct: 148 K-PGPQGYPGVGKPG--------------------MPGMPG-KPGAMGMPGAKGEIGQKG 185 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G+PG P P G+PG PG P + K G R G+ G P Sbjct: 186 EIGPMGIPGPQGPPGPH-GLPGIGKPG--GPGLPGQPGPK----GDRGPKGLPG-PQGLR 237 Query: 405 GAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVG 464 G G GFG+ G PGV G PG+ G PG G+PGVG PGV Sbjct: 238 GPKGDKGFGMP--GAPGVKGPPGMHGPPGPVGLPGVG------------------KPGVT 277 Query: 465 VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKA 524 PG G APG G PGV PG+ PGIG G K Sbjct: 278 GFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKG 334 Query: 525 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-AAKAAKYGA 583 + G+PGL G+PG+ G PG G G G VPGAL + GA Sbjct: 335 E--------QGLPGLPGPPGLPGI----GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGA 382 Query: 584 ----------AVPGVLGGLGALGGVGIP-----GGVVG----AGPAAAAAAAKAAAKAAQ 624 +PG+ G +G G +G P GG+VG GP K Sbjct: 383 PGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGF 442 Query: 625 FGLVGAAGLGGL-----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G VG G+ GL G G GV GL G+P K + G+ G P PG Sbjct: 443 LGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPK-GEPGIPGDQGLQGPPGIPG 501 Score = 110 bits (276), Expect = 3e-24 Identities = 139/415 (33%), Positives = 164/415 (39%), Gaps = 76/415 (18%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGG-----GALGPGGKPLKPVPGGLAGAGL 75 P PG G PG G PG V PG G + G G LG G P +P P G G Sbjct: 248 PGAPGVKGPPGM--HGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305 Query: 76 GAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVV 134 G P + PG +PG + K GL G+PG GL P PG Sbjct: 306 VQGPPGIPGIGKPGQDGIPG-----QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG--- 357 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGI 194 P+ G+ G VPG P G + GA PG+G PG P G+ P G GA G Sbjct: 358 PKGDRGM--GGVPGALGPRGEKGPI--GA--PGIGGPPGEPGLPGI-PGPMGPPGAI-GF 409 Query: 195 PG-------VGPFGGPQP-GVP--LGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAA 244 PG VGP G P P G P G+P K P G G P G LP GP G AG Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-PGFLGEVGPPGMRG-LPGPIGPKGEAGQK 467 Query: 245 GKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIG 298 G G P G+ GP+ + G G+ G G PG+PG +PG Sbjct: 468 GVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPP 527 Query: 299 GIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPGAGI 356 G G+G P A K PG GP PG+ G PG PG P A + Sbjct: 528 GFPGIGKPGVAGLHGPPGK-----------PGALGPQGQPGLPGPPGP--PGPPGPPAVM 574 Query: 357 PVVP---GAGIP--GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 P P G +P G + GV P A YGA+ G G P Y + A Sbjct: 575 PPTPPPQGEYLPDMGLGIDGVKPPHA----------YGAKKGKNGG--PAYEMPA 617 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 147 bits (372), Expect = 2e-35 Identities = 232/772 (30%), Positives = 280/772 (36%), Gaps = 145/772 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGA------- 73 P PG G PG + PG L G G GP G P P P G GA Sbjct: 538 PGPPGRDGSKGMRGEPGELGEPG-----LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGER 592 Query: 74 ---GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG-VGGLGVSAAPSV 129 G G FPG PG + +G+ G G G +G + P V Sbjct: 593 GEKGTRGEKGERGLDGFPGK--PGDTGQ-----QGRPGPSGVAGPQGEKGDVGPAGPPGV 645 Query: 130 PGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPK----- 183 PG+VV Q G + G G G PG PGAR P G G P G++ K Sbjct: 646 PGSVVQQEGLKGEQGAPGPRGHQGA-PGP--PGARGPIGPEGRDGPPGLQGLRGKKGDMG 702 Query: 184 APGVGGAFA-----GIPGV-GPFG-GPQPGVP--LGYPIKAPKLPGGYGLPYTTGK--LP 232 PG+ G G PGV GP G G PG+P +G+P K P PG G P G P Sbjct: 703 PPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK-PGPPGPTGPPGKDGPNGPP 761 Query: 233 YGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGV--LPGV------- 282 G G G G+ G P G+ G A + K AG G PGV Sbjct: 762 GPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQ 821 Query: 283 ---GGAGVPGV-----------PGAIPGIGGIAGVGTPAAAAAAAAAAKAAK-------- 320 G G+PG+ P PG+ G + TP K K Sbjct: 822 GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE 881 Query: 321 ---YGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPG-AGIPG-AAVPGVVS 374 G L P GP PG G GA G PG AG P PG G PG + PG V Sbjct: 882 PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG----AAGNPGAPGHVGAPGPSGPPGSVG 937 Query: 375 PEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVG--GVP 432 K + G + G G P VG G P G PG+ G PG G G P Sbjct: 938 APGLRGTPGKDGERGEKGAAGEEGSPG-PVGPRGDP-------GAPGLPGPPGKGKDGEP 989 Query: 433 GVGGVPGVGISPEAQAAAAAK-------AAKYGLVPGVGVAPGVGVAPGVGVAPGVGLA- 484 G+ G PG+ P AA K A V G APG+ +PG PG+G+A Sbjct: 990 GLRGSPGLP-GPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG 1048 Query: 485 -PGVGVAPGVGVAPGVGVAPGI----GPGGVAAAAKSAAK--VAAKAQLRAAAGLG---- 533 PG PG +PG PG GP G A + + K L + G Sbjct: 1049 PPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINL 1108 Query: 534 ----------------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAK 577 G+PG GVPG G G AG PG PG +A + Sbjct: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-IAGPQ 1167 Query: 578 AAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL---- 633 ++ G +G G G G+PG + G A A A G+ G+ G Sbjct: 1168 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPP 1227 Query: 634 GGLGVGGL-GVPGVGGLGGI-----PPAAAAKAAKYGVAARPGFGLSPIFPG 679 G G GL G+PG G G PP KA + G+ G P F G Sbjct: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 1279 Score = 132 bits (332), Expect = 1e-30 Identities = 197/648 (30%), Positives = 232/648 (35%), Gaps = 82/648 (12%) Query: 59 GGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPG---GVADAAAAYKAAKAGAGLGGV 115 G K V G + G +GA V PG G+ K K GL G Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540 Query: 116 PGVGGL-------GVSAAPSVPGAV---VPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGA 163 PG G G P +PG V PQ PG PG+V GL G G Sbjct: 541 PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600 Query: 164 RFP-GVGVLPGVP--TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPG 220 + G+ PG P TG +P GV G VGP G PGVP G ++ L G Sbjct: 601 KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG--PPGVP-GSVVQQEGLKG 657 Query: 221 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLP 280 G P G G G GA G G P G GP K G G+L Sbjct: 658 EQGAPGPRGH----QGAPGPPGARGPIG-PEGRD-GPPGLQGLRGKKGDMGPPGIPGLLG 711 Query: 281 GVGGAGVPGVPGAIPGIGGIAG----VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGP 336 G G PGVPG PG GG G +G P K G P GP P Sbjct: 712 LQGPPGPPGVPGP-PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG------PNGPPGPP 764 Query: 337 GVVGVPGA----GVPG-------VGVPG-AGIPVVPG-AGIPGA-AVPGVVSPEAAAKAA 382 G G PG G+PG +G G AG P G AG+PGA PGV + Sbjct: 765 GTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 824 Query: 383 AKAAKYGARPGVGVGGIPTYGVGAGGFPGFG---------VGVGGIPGVAGVPGVGGVPG 433 + G + G G G G PG G G G G PG+ G PG Sbjct: 825 GELGLPGLKGDRGEKG-EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883 Query: 434 VGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV 493 + G PG + P+ + G APG PG APG APG PG Sbjct: 884 LQGRPG-ELGPQGPTGPPGAKGQ----EGAHGAPGAAGNPG---APGHVGAPGPSGPPGS 935 Query: 494 GVAPGVGVAPG----IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLG 549 APG+ PG G G A S V + A GL G PG G G PGL Sbjct: 936 VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGD-PGAPGL-PGPPGKGKD-GEPGLR 992 Query: 550 VGAGVPG-LGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG--GVGIPGGVVG 606 G+PG LG A + K PG+ G G+ G G+G+ G Sbjct: 993 GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGP 1052 Query: 607 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGI 652 +GP + + G G AG G G G PG GL + Sbjct: 1053 SGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100 Score = 116 bits (290), Expect = 8e-26 Identities = 216/734 (29%), Positives = 247/734 (33%), Gaps = 114/734 (15%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGA-GLGALGG-----GALGPGGKPLKPVPGGLAGA-G 74 +P PG V P G PG V PG G G GA G G P P G GA G Sbjct: 917 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976 Query: 75 L----GAGLGAFPAVT-FPGALVPGGVADAAAAYKA-AKAGAGLGGVPGVGGLGVSAAPS 128 L G G P + PG +PG + AA K LGG G G P Sbjct: 977 LPGPPGKGKDGEPGLRGSPG--LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPG 1034 Query: 129 VPGAVVPQPGAGVK--PGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPG 186 PG+ PG GV PG G G LPG FPG P P G P PG Sbjct: 1035 SPGSR-GDPGIGVAGPPGPSGPPGDKGSPGSRGLPG--FPG----PQGPAGRDGAPGNPG 1087 Query: 187 VGGAFAGIPGVGPFGGPQP----------GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 236 G G PG+ P P G P P LPG G GK P G Sbjct: 1088 ERGP-PGKPGLSSLLSPGDINLLAKDVCNDCPPGPP-GLPGLPGFKGDKGVPGK-PGREG 1144 Query: 237 PGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVPGAIP 295 G G AG G P G+ + A + G PGV G G PG PG P Sbjct: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP-P 1203 Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGL--VPG-----------GPGFGPGVVGVP 342 G GIAG P + +GL +PG GP PG G P Sbjct: 1204 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263 Query: 343 GA-------GVPGV-------GVPG----AGIPVVPGA-GIPG----AAVPGVVSPEAAA 379 G G PG G PG +G +PG G+PG G P+ Sbjct: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323 Query: 380 KAAAKAAKYGARPGVGVGGIPTYGVGAG-----GFPGF--GVGVGGIPGVAGVPGVGGVP 432 K G+ G G P G G PGF G G PG GVPG GVP Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 1383 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGL-VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAP 491 G G PG K G PG PG G+ G+ G P Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP 1443 Query: 492 GVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLG-------------AGIPG 538 G PG G P ++ + + R A L G PG Sbjct: 1444 GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG 1503 Query: 539 LGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGV 598 G+PG G PG G+ G + P + AK PGV G G +G Sbjct: 1504 PPGKDGLPGRAGPMGEPGRPGQGGLEG-PSGPIGPKGERGAKGDPGAPGV-GLRGEMGPP 1561 Query: 599 GIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAA 658 GIPG G A+ GL G G G G G PG+ G G P Sbjct: 1562 GIPGQPGEPG-------------YAKDGLPGIPGPQG-ETGPAGHPGLPGPPGPPGQCDP 1607 Query: 659 KAAKY--GVAARPG 670 Y +AARPG Sbjct: 1608 SQCAYFASLAARPG 1621 Score = 114 bits (284), Expect = 4e-25 Identities = 190/609 (31%), Positives = 221/609 (36%), Gaps = 104/609 (17%) Query: 110 AGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGV 168 AG G GV G +G+ GA+ P G K K G G+ P G + Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEK----GDVGIGPFGQGEKGEKGSL 535 Query: 169 GVLPGVPTGAGVKPKA--PGVGGAFAGIPGVGPFGGPQ--PGVPLGYP--IKAPKLPGGY 222 G LPG P G K PG G G+PG GPQ PG+P G P + AP L G Sbjct: 536 G-LPGPPGRDGSKGMRGEPGELGE-PGLPGEVGMRGPQGPPGLP-GPPGRVGAPGLQGER 592 Query: 223 GLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV 282 G T G+ G G+ G GK G TG P + A G G V Sbjct: 593 GEKGTRGEK----GERGLDGFPGKPG-DTGQQGRPGPSGVA----------GPQGEKGDV 637 Query: 283 GGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGV 341 G AG PGVPG++ G+ G G P A GA + P G PG+ G+ Sbjct: 638 GPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPP---GARGPIGPEGRDGPPGLQGL 694 Query: 342 PGA----GVPGVGVPGA-GIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVG 395 G G PG+ PG G+ PG G+PG PG G Sbjct: 695 RGKKGDMGPPGI--PGLLGLQGPPGPPGVPGPPGPG-----------------------G 729 Query: 396 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 455 G+P G GFPG G PG G PG G G G PG P + Sbjct: 730 SPGLP----GEIGFPG----KPGPPGPTGPPGKDGPNGPPGPPGTKGEP-GERGEDGLPG 780 Query: 456 KYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGV-GVAPGVGVAPGIGPGGVAA-- 512 K GL +G G+ PG G+ APG PGV G G +G G+ Sbjct: 781 KPGLRGEIG-EQGLAGRPGEKGEAGLPGAPGF---PGVRGEKGDQGEKGELGLPGLKGDR 836 Query: 513 AAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGA 572 K A A L L P + G G G PGL G PG PG Sbjct: 837 GEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG---EKGDPGL---PGEPGLQGRPGE 890 Query: 573 LA--------AAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQ 624 L AK + PG G GA G VG PG G A K + Sbjct: 891 LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950 Query: 625 FGLVGAAGLGGLG--VGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPGGAC 682 G GAAG G VG G PG GL G PP G PG SP PG Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGLPG-PPGK-------GKDGEPGLRGSPGLPGPLG 1002 Query: 683 LGKACGRKR 691 ACG+ R Sbjct: 1003 TKAACGKVR 1011 Score = 111 bits (278), Expect = 2e-24 Identities = 189/653 (28%), Positives = 229/653 (35%), Gaps = 109/653 (16%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGK-----------PLKPVPGGLAGAGLG 76 G PG IPG PG PG G+ G + PG K P P G GA Sbjct: 1028 GAPG-IPGS-PGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085 Query: 77 AGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAVVP 135 G P +L+ G + A G G+PG+ G G P PG Sbjct: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG---- 1141 Query: 136 QPGAGVKPGKVPGVGLPGVYPGGVLP----GAR-------------FPGVGVLPGVPTGA 178 + G K G+ GLPG PG P G R PGV G P Sbjct: 1142 REGTEGKKGEAGPPGLPGP-PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200 Query: 179 GVKPKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYG 234 G P A G+ GA AG PG+ G G P P P G P +PG G GK Sbjct: 1201 G-PPGADGIAGA-AGPPGIQGSPGKEGPPGPQGPSGLP----GIPGEEGKEGRDGKP--- 1251 Query: 235 YGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAI 294 GP G G AG+ G P GP+ A +GA G G G+PG G + Sbjct: 1252 -GPPGEPGKAGEPGLP-----GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG-L 1304 Query: 295 PGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA---------- 344 PG G G P K G+ PG PG PG G PG Sbjct: 1305 PGKDGDTGPTGPQGPQGPRGPP--GKNGS-----PGSPG-EPGPSGTPGQKGSKGENGSP 1356 Query: 345 GVPGV----GVPGA-GIPVVPGA-GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVG 397 G+PG G PG G VPG G+PG PG G + G Sbjct: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 1416 Query: 398 GIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAK 456 GIP G G G +G G+PG G G G PG G PG+ G SP + + Sbjct: 1417 GIP----GHKGHTGL-MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471 Query: 457 YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAK 515 G +A + P + G PG PG PG G G G Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQG-RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530 Query: 516 SAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAA 575 + + K + A GA GL +G PG+ G PG G+PG Sbjct: 1531 PSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-GLPG---------- 1579 Query: 576 AKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLV 628 +PG G G G G+PG G + A A+ AA+ G V Sbjct: 1580 ---------IPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 146 bits (368), Expect = 7e-35 Identities = 170/541 (31%), Positives = 204/541 (37%), Gaps = 55/541 (10%) Query: 117 GVGGLGVSAAPSVPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGV 174 G+ G P PG P+ PG PGK PG PG+ PG+ Sbjct: 52 GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGK---------------PGYGSPGLQGEPGL 96 Query: 175 PTGAGVKPKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYPIKAPK-LPGGYGLPYTTG 229 P G P A G G G+PG GP+G P G P P+ PG G+P G Sbjct: 97 PGPPG--PSAVGKPGV-PGLPGKPGERGPYGPKGDVGPAGLP--GPRGPPGPPGIPGPAG 151 Query: 230 -KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVP 288 +P G G GA G G+P G P K +GA G+ G P Sbjct: 152 ISVPGKPGQQGPTGAPGPRGFPGEKG-APGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP 210 Query: 289 GVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPG 348 P PG+G G P + G + P GP PG G G G PG Sbjct: 211 TGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGP---IGPPGPQGPPGERGPEGIGKPG 267 Query: 349 -VGVPGAGIPVVPGA-GIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 G PG P +PG G+PGA PG+ P K G + G G+P G GA Sbjct: 268 AAGAPGQ--PGIPGTKGLPGA--PGIAGP-PGPPGFGKPGLPGLKGERGPAGLPG-GPGA 321 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGV-GISPEAQAAAAAKAAKYGLVPGVGV 465 G G G+ G PG+ G PG G G G+PG G+ A A Y G Sbjct: 322 KGEQG-PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKA 524 +PG PG PG+ G PG PGVG PG+ GP G A AK +A Sbjct: 381 SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVG-PAGAKGMPGHNGEA 439 Query: 525 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG-ALAAAKAAKYGA 583 R A GIPG +G P G+PG G PG PG A A K Sbjct: 440 GPRGA----PGIPGTRGPIGPP------GIPGFPGSKGDPGSPGPPGPAGIATKGLNGPT 489 Query: 584 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 643 PG G G G G+PG GP A + KA Q + L G G+ Sbjct: 490 GPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549 Query: 644 P 644 P Sbjct: 550 P 550 Score = 124 bits (310), Expect = 4e-28 Identities = 164/533 (30%), Positives = 188/533 (35%), Gaps = 101/533 (18%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGL-------GALGGGALG-PG--GKPLKPVPGGLAG 72 P+ P G PG P G PG Y GL G G A+G PG G P KP G G Sbjct: 67 PAGPRGHPG--PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYG 124 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGA-GLGGVPGVGGL-GVSAAPSVP 130 G P P P G+ A K G G G PG G G AP VP Sbjct: 125 PKGDVGPAGLPGPRGPPG--PPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVP 182 Query: 131 GAVVPQPGAGV-KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG 189 G + G PG+ GLPG P G + PGVG G P PG+ G Sbjct: 183 GMNGQKGEMGYGAPGRPGERGLPG--PQGPTGPSGPPGVG-----KRGENGVPGQPGIKG 235 Query: 190 AFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G PG +GP G P P P PG G P G G G AGA G+ G Sbjct: 236 D-RGFPGEMGPIGPPGPQGP----------PGERG--------PEGIGKPGAAGAPGQPG 276 Query: 249 YPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAA 308 P G+ P A A PG G G+PG+ G G G G Sbjct: 277 IPGTKGL-PGAPGIAGPPGP-----------PGFGKPGLPGLKGERGPAGLPGGPGAKGE 324 Query: 309 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----------AGVPGV----GVPGA 354 A K G + P GP PG G+PG AG PG G PG+ Sbjct: 325 QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGS 384 Query: 355 ----GIPVVPG-------AGIPG-------AAVPGVVSPEAAAKAAAKAAKYGARPGVGV 396 G P PG G+PG PG+ P A A G G Sbjct: 385 DGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA 444 Query: 397 GGIP-TYG-VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKA 454 GIP T G +G G PGF PG G PG G PG G+ G++ Sbjct: 445 PGIPGTRGPIGPPGIPGF-------PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGP 497 Query: 455 AKYGLVPGVGVAPGVGVAPGVGVAP----GVGLAPGVGVAPGVGVAPGVGVAP 503 + PG+ PG PG V P G P + P V GV P Sbjct: 498 RGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550 Score = 111 bits (277), Expect = 3e-24 Identities = 148/482 (30%), Positives = 176/482 (36%), Gaps = 86/482 (17%) Query: 198 GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGY----GPGGVAGAAGKAGYPTGT 253 G F + +P G P + +PYT G G G AG G+P Sbjct: 18 GVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHP--- 74 Query: 254 GVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAA 313 GP +G G PG G G+ G PG +PG G + VG P Sbjct: 75 --GP---------------SGPPGK-PGYGSPGLQGEPG-LPGPPGPSAVGKPGVPGLPG 115 Query: 314 AAAKAAKYGAAAGLVPGG---PGFGPGVVGVPG-AGVPGVGVPGAGIPV-VPGA-GIPGA 367 + YG + P G P PG G+PG AG+ G PG P PG G PG Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175 Query: 368 -AVPGVVSPEAAAKAAAKAAKYGA--RPGV-GVGGIPTYGVGAGGFPGFGV-GVGGIPGV 422 PGV YGA RPG G+ G P G G PG G G G+PG Sbjct: 176 KGAPGVPGMNGQKGEMG----YGAPGRPGERGLPG-PQGPTGPSGPPGVGKRGENGVPGQ 230 Query: 423 AGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVG 482 G+ G G PG G G P Q + + G+G PG APG PG Sbjct: 231 PGIKGDRGFPGEMGPIG---PPGPQGPPGERGPE-----GIG-KPGAAGAPGQPGIPGTK 281 Query: 483 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG 542 PG APG+ PG PG G G+ L+ G AG+PG G Sbjct: 282 GLPG---APGIAGPPG---PPGFGKPGLPG-------------LKGERG-PAGLPG---G 318 Query: 543 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA--AAKAAKYGAAVPGVLGGLGALGGVGI 600 G G AG+PG PG PG + K +PG G G G G Sbjct: 319 PGAKGEQGPAGLPGK------PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372 Query: 601 PGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKA 660 PG G + K GL G G GL G G PGVGG G+P Sbjct: 373 PGAKGERGSPGSDGKPGYPGKP---GLDGPKGNPGLP-GPKGDPGVGGPPGLPGPVGPAG 428 Query: 661 AK 662 AK Sbjct: 429 AK 430 Score = 70.1 bits (170), Expect = 7e-12 Identities = 93/301 (30%), Positives = 110/301 (36%), Gaps = 67/301 (22%) Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 G G PG G G G PG G PG YG PG+ PG+ PG Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPG--------------KPGYG-SPGLQGEPGLPGPPG 101 Query: 475 VGVA--PGVGLAPG-------------VGVA--PGVGVAPGVGVAPGI-GPGGVAAAAKS 516 PGV PG VG A PG PG PGI GP G++ K Sbjct: 102 PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPG---PPGIPGPAGISVPGKP 158 Query: 517 AAK--VAAKAQLRAAAGLGA-GIPGLG-----VGVGVPGLGVGAGVPGL--------GVG 560 + A GA G+PG+ +G G PG G+PG G Sbjct: 159 GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG 218 Query: 561 AGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGAGPAAAAAAAKA 618 G G VPG K PG +G +G G G PG G G G AA A Sbjct: 219 VGKRGENGVPG----QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQ 274 Query: 619 AAKAAQFGLVGAAGLGG-LGVGGLGVPGVGGL------GGIP--PAAAAKAAKYGVAARP 669 GL GA G+ G G G G PG+ GL G+P P A + G+ +P Sbjct: 275 PGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP 334 Query: 670 G 670 G Sbjct: 335 G 335 Score = 48.5 bits (114), Expect = 2e-05 Identities = 66/226 (29%), Positives = 77/226 (34%), Gaps = 45/226 (19%) Query: 460 VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGI-GPGGVAAAAKSAA 518 V G PG G PG PG PG G +PG+ PG+ GP G +A K Sbjct: 55 VRGEQGTPGPPGPAGPRGHPGPSGPPG---KPGYG-SPGLQGEPGLPGPPGPSAVGKPGV 110 Query: 519 KVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKA 578 G+PG G G G GL G PG +PG + Sbjct: 111 P---------------GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP 155 Query: 579 AKYGAAVPGVLGGLGALGGVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGL 633 K PG G GA G G PG GV G A + + GL G G Sbjct: 156 GK-----PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQG- 209 Query: 634 GGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G G PGVG K + GV +PG FPG Sbjct: 210 ---PTGPSGPPGVG-----------KRGENGVPGQPGIKGDRGFPG 241 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 145 bits (367), Expect = 9e-35 Identities = 204/702 (29%), Positives = 256/702 (36%), Gaps = 102/702 (14%) Query: 23 PSRPGGVPGAI----PGGVPGGVFYPGA-GLGALGGGALGPGGKPLKPVPGGLAGAGLGA 77 P P G+PG P G+PG PG GL G PG P +PVPG GL Sbjct: 499 PPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSG 558 Query: 78 -----------GLGAFPAVT-FPGAL-VPGGVAD-AAAAYKAAKAGAGLGGVPG-VGGLG 122 GL P + PG +PG + + Y + AG G PG G G Sbjct: 559 LMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQG 618 Query: 123 VSAAPSVPGAVVPQ-----PGAGVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPT 176 +P G + P+ PG K G G PG + G R P G+ PG+ Sbjct: 619 FIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF------GDRGPAGLDGSPGLVG 672 Query: 177 GAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 236 G G P PG+ G+ + +GP G P P+G L G GLP G G Sbjct: 673 GTG-PPGFPGLRGSVGPVGPIGPAGIPG---PMG-------LSGNKGLPGIKG----DKG 717 Query: 237 PGGVAGAAGKAGYPTGTG-VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--A 293 G AG G+ GYP G VG K+ G G+ G G G PG Sbjct: 718 EQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIG 777 Query: 294 IPGIGGIAGV-------GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AG 345 IPG G G G P + GA L P G G G PG G Sbjct: 778 IPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEG 837 Query: 346 VPG-VGVPG--AGIPVVPGAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPT 401 + G VG G I G+PG + G + + + G + +G G P Sbjct: 838 LKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPG 897 Query: 402 Y--GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPG-VGI-SPEAQAAAAAKAAKY 457 +G G PG VG G PG G G G G G+ G GI + + K + Sbjct: 898 VPGPIGPLGLPGH-VGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956 Query: 458 GLVPGVG--VAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGVA 511 GL+ G G PG+ PG G+ PG+ G PG GP G Sbjct: 957 GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016 Query: 512 AAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG 571 + + AK + A +G G G PGL G PG G G VPG Sbjct: 1017 GESGLQGEPGAKGDVGTAGSVG--------GTGEPGLRGEPGAPGEEGLQGKDGLKGVPG 1068 Query: 572 --ALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVG----------------AGPAA 611 L K +PG++G LG G G+PG G+VG GP Sbjct: 1069 GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTG 1128 Query: 612 AAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 653 + K + G GA G G VG LG+ G G GIP Sbjct: 1129 EVGSRGPPGKIGKSGPKGARGTRG-AVGHLGLMGPDGEPGIP 1169 Score = 114 bits (285), Expect = 3e-25 Identities = 222/816 (27%), Positives = 277/816 (33%), Gaps = 193/816 (23%) Query: 22 HPSRPGGVPG--AIPG--GVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPGGLAGAGLG 76 HP PG +PG IPG G G YPG G GP G P K G + G Sbjct: 574 HPGLPG-LPGEQGIPGFAGNIGSPGYPGRQ------GLAGPEGNPGPKGAQGFIGSPGEA 626 Query: 77 AGLGAFPAVTFPGAL----------VPGGVADAAAAYKAAKAGAGLGGVPG-VGGLGVSA 125 LG PG PG D + AGL G PG VGG G Sbjct: 627 GQLGPEGERGIPGIRGKKGFKGRQGFPGDFGD--------RGPAGLDGSPGLVGGTGPPG 678 Query: 126 APSVPGAVVPQPGAGVKPGKVPGV-------GLPGVY-------PGGVLPGARFPGVGVL 171 P + G+V P G P +PG GLPG+ G L +PG Sbjct: 679 FPGLRGSVGPVGPIG--PAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGA 736 Query: 172 PGVPTGAGVKPKAPGVGGAFAGIPGV-GPFGGPQP-------GVPLGYPIKAPK------ 217 G+P G++ K+ G G PG+ GP G P P G+P + PK Sbjct: 737 VGLPGPPGMRGKSGPSGQT--GDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNR 794 Query: 218 -LPGGYGLPYTTGKL-PYG----YGPGGVAGAAGKAGYPTGTG----------------- 254 PG GL T G+ P G GP G G G AG P G Sbjct: 795 GPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGET 854 Query: 255 --VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAG-VGTPAAAAA 311 VG K G+ G L G GV G PG PG+ G G +G P A Sbjct: 855 GPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGP-PGVPGPIGPLGLPGHVGA 913 Query: 312 AAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------------------------GV 346 G P G G+ G G G Sbjct: 914 RGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGK 973 Query: 347 PGV-GVPGA----GIPVVPGA-GIPGAAVP----GVVSPEAAAKAAAKAAKYGARPGVGV 396 PG+ G+PG+ G+P PG G+ G P G+ P + + GA+ VG Sbjct: 974 PGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGT 1033 Query: 397 GGIPTYGVGAGGFPGF----------GV----GVGGIPGVAGVPGVGGVPGVGGVPGVGI 442 G VG G PG G+ G+ G+PG G+PG G G G+PG+ I Sbjct: 1034 AG----SVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGI-I 1088 Query: 443 SPEAQAAAAAKAAKYGLV--PGVGVAPG-------VGVAPGVGVA--PG-VGLAPGVGVA 490 P ++ G+V PG PG +G VG PG +G + G Sbjct: 1089 GPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGAR 1148 Query: 491 PGVGVAPGVGVA-----PGI----------------GPGGVAAAAKSAAKVAAKAQLRAA 529 G +G+ PGI GP G + V R Sbjct: 1149 GTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGE 1208 Query: 530 AG-LG-------AGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAA----- 576 G +G G G VGVPGL G G G G + G + Sbjct: 1209 PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGK 1268 Query: 577 KAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGL 636 K A + PG+ G G LG GI G G + K G+ G G GL Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328 Query: 637 GVGGLGVPGVGGLGGIP--PAAAAKAAKYGVAARPG 670 G G PGV G G+P P + G+ +PG Sbjct: 1329 A-GAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPG 1363 Score = 104 bits (259), Expect = 3e-22 Identities = 194/668 (29%), Positives = 233/668 (34%), Gaps = 126/668 (18%) Query: 26 PGGVPGAI-PGGVPG-----------------GVFYPGAGLGALG-GGALGPGGKPLKPV 66 P GVPG I P G+PG G P LG G GA G G K Sbjct: 895 PPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRG 954 Query: 67 PGGLAGAGLGAGLGAFPAVTFPGAL-VPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSA 125 P GL G G F PG +PG D + G G V G +G+ Sbjct: 955 PHGLIGKTGNPGERGFQGK--PGLQGLPGSTGDRGLPGEPGLRGLQ-GDVGPPGEMGMEG 1011 Query: 126 APSVPGAVVPQPGAGVK-----PGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGVPTGAG 179 P G Q G K G V G G PG+ PG G L GVP G G Sbjct: 1012 PPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071 Query: 180 VKPKAPGVGGAFAGIPGV-GPFG-GPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGP 237 + P G G G+PG+ GP G Q G+P P +PG G P Sbjct: 1072 L-PGEDGEKGEM-GLPGIIGPLGRSGQTGLP--GPEGIVGIPGQRGRP------------ 1115 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G G+ G PTG VG + K+ K G G + +G G G PG IPG Sbjct: 1116 -GKKGDKGQIG-PTGE-VGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPG-IPGY 1171 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGV-GVPG-A 354 G G P+ K + L P GP PG VG G G PG G G Sbjct: 1172 RGHQGQPGPSGLPGPKGE-KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHV 1230 Query: 355 GIPVVPGA----GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG--VGAG 407 G+P + GA G PG G + + K GA G GIP +G Sbjct: 1231 GVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPK 1290 Query: 408 GFPGF--GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGV 465 G G+ G+ G PG G PG G+PG+ G PG Sbjct: 1291 GIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPG-------------------------- 1324 Query: 466 APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQ 525 G+ APG PGV + G+ +PG+ G PG PG + K Sbjct: 1325 RTGLAGAPG---PPGVKGSSGLPGSPGIQGPKGEQGLPG-QPG-----------IQGKRG 1369 Query: 526 LRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAV 585 R A G G PGL G PG G+ GF PG K + A + Sbjct: 1370 HRGAQGDQG-------PCGDPGL---KGQPGEYGVQGLTGFQGFPG----PKGPEGDAGI 1415 Query: 586 PGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPG 645 G+ G G +G G GP + G G G G G G PG Sbjct: 1416 VGISGPKGPIGHRG------NTGPLGREGIIGPTGRTGPRGEKGFRGETG-PQGPRGQPG 1468 Query: 646 VGGLGGIP 653 G G P Sbjct: 1469 PPGPPGAP 1476 Score = 78.2 bits (191), Expect = 2e-14 Identities = 130/447 (29%), Positives = 163/447 (36%), Gaps = 61/447 (13%) Query: 28 GVPGAI-PGGVPGGVFYPGA-GLGALGG-----------GALGPGGKP-LKPVPGGLAGA 73 G+PG I P G G PG G+ + G G +GP G+ + PG + + Sbjct: 1083 GLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS 1142 Query: 74 GLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAV 133 G G AV G + P G Y+ + G G+PG G P V Sbjct: 1143 GPKGARGTRGAVGHLGLMGPDG-EPGIPGYRGHQGQPGPSGLPGPKG--EKGYPGEDSTV 1199 Query: 134 VPQPGAGVKPGKVPGVGLPGVYPGGVLPGAR-FPGVGVLPGV--PTGAGVKPKAPGVGGA 190 + PG +PG V G G PGA + G +PG+ TG P PG G Sbjct: 1200 LGPPGPRGEPGPVGDQGERGE------PGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGE 1253 Query: 191 FAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYP 250 G+ G G + P P +PG GL G Y +G G++G GK G P Sbjct: 1254 -QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGY-HGADGISGNPGKIGPP 1311 Query: 251 TGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGV-GGAGVPGVPGAIPGIGGIAGV-GTPAA 308 G Q AGA G PGV G +G+PG PG I G G G+ G P Sbjct: 1312 -----GKQGLPGIRGGPGRTGLAGAPGP-PGVKGSSGLPGSPG-IQGPKGEQGLPGQPGI 1364 Query: 309 AAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGAGIPVVPGAGIP-- 365 K G GP PG+ G PG GV G+ G PG P Sbjct: 1365 QG---------KRGHRGAQGDQGPCGDPGLKGQPGEYGVQGL----TGFQGFPGPKGPEG 1411 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 A + G+ P+ G +G PT G G GF G G G Sbjct: 1412 DAGIVGISGPKGPIGHRGNTGPLGREGIIG----PTGRTGPRGEKGFR----GETGPQGP 1463 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAA 452 G G PG G PG + AA A Sbjct: 1464 RGQPGPPGPPGAPGPRKQMDINAAIQA 1490 Score = 76.6 bits (187), Expect = 7e-14 Identities = 123/477 (25%), Positives = 170/477 (35%), Gaps = 77/477 (16%) Query: 230 KLPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 289 ++ Y GP G G G G P G GP G G+ G G+PG Sbjct: 483 EMEYLRGPKGDTGPPGPPG-PAGIP-GPSGKR------------GPRGIPGPHGNPGLPG 528 Query: 290 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPG 348 +PG G P + + G + + P G G+ G PG G+PG Sbjct: 529 LPGP------KGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPG 582 Query: 349 -VGVPG----AGIPVVPG-------------------AGIPGAA----------VPGVVS 374 G+PG G P PG G PG A +PG+ Sbjct: 583 EQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRG 642 Query: 375 PEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVGVGGIPGVAGVPGVGG 430 + +G R G+ G P G G GFPG VG G G AG+PG G Sbjct: 643 KKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMG 702 Query: 431 VPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVA 490 + G G+PG+ + + A + + G PG A G+ PG+ G G Sbjct: 703 LSGNKGLPGIK-GDKGEQGTAGELGEPG-YPGDKGAVGLPGPPGMRGKSGPSGQTGDPGL 760 Query: 491 PGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGV 550 G PG P PG + ++ + K L G PGL G G Sbjct: 761 QGPSGPPG----PEGFPGDIGIPGQNGPE-GPKGLLGNRG--PPGPPGLKGTQGEEGPIG 813 Query: 551 GAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG--GVVGA- 607 G G G G+ PG + K G +G +G G VG+PG G+ G+ Sbjct: 814 AFGELGPRGKPGQKGYAGEPG----PEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSI 869 Query: 608 GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGGLGVPGVGGLGGIPPAAAAKAAK 662 G + + G++G G G+ +G LG+PG G G P + K + Sbjct: 870 GEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQR 926 Score = 67.0 bits (162), Expect = 6e-11 Identities = 81/278 (29%), Positives = 99/278 (35%), Gaps = 25/278 (8%) Query: 410 PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAK--YGLVPGVGV-- 465 P G G PG AG+PG G G G+PG +P K K G PG V Sbjct: 490 PKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPG 549 Query: 466 ------APGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAK 519 G+ PG+ G+ PG+ PG P G A IG G A Sbjct: 550 EKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIP--GFAGNIGSPGYPGRQGLAGP 607 Query: 520 VAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAA 579 A +G+ PG +G G G+PG+ G G PG A Sbjct: 608 EGNPGPKGAQGFIGS--PGEAGQLGPEG---ERGIPGIRGKKGFKGRQGFPGDFGDRGPA 662 Query: 580 KYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG-LGGLGV 638 + PG++GG G G G+ G V GP A + GL G G G G Sbjct: 663 GLDGS-PGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQGT 721 Query: 639 GG-LGVPGVGGLGGI-----PPAAAAKAAKYGVAARPG 670 G LG PG G G PP K+ G PG Sbjct: 722 AGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPG 759 Score = 60.5 bits (145), Expect = 5e-09 Identities = 93/343 (27%), Positives = 112/343 (32%), Gaps = 76/343 (22%) Query: 19 SILHPSRPGGVPGAIPG----GVPGGVFYPG-AGLGALGG--GALGPGGKPLKPVPGGLA 71 ++L P P G PG + G PG Y G G+ L G G GP G+P GL Sbjct: 1198 TVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLK 1257 Query: 72 GAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPG 131 G G K K G G PG+ GL P Sbjct: 1258 GERGSEG------------------------NKGKKGAPGPSGKPGIPGLQGLLGPKGIQ 1293 Query: 132 AVVPQPGAGVKPGKV--PGV-GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVG 188 G PGK+ PG GLPG+ G PG TG P PGV Sbjct: 1294 GYHGADGISGNPGKIGPPGKQGLPGIRGG---PGR------------TGLAGAPGPPGVK 1338 Query: 189 GAFAGIPGVGPFGGP--QPGVPLGYPIKAPKLPGGYGLPYTTGKLPY--GYGPGGVAGAA 244 G+ +G+PG GP + G+P G P GK + G G G Sbjct: 1339 GS-SGLPGSPGIQGPKGEQGLP--------------GQPGIQGKRGHRGAQGDQGPCGDP 1383 Query: 245 GKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVG 304 G G P GV Q K G AG++ G+ G G I G +G Sbjct: 1384 GLKGQPGEYGV--QGLTGFQGFPGPKGPEGDAGIV------GISGPKGPIGHRGNTGPLG 1435 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVP 347 + G P GP PG G PGA P Sbjct: 1436 REGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGP 1478 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 144 bits (364), Expect = 2e-34 Identities = 217/688 (31%), Positives = 260/688 (37%), Gaps = 105/688 (15%) Query: 22 HPSRPGGVPGAIPGGVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 +P PG A P G PG + P G +GG G GP G P P G G +GL Sbjct: 2151 NPGLPGERGMAGPEGKPG-LQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP---SGLK 2206 Query: 81 AFPAVTFPGALVPG-GVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPSVPGAV--VPQ 136 P T P PG G+ A GL G PG GL G +P +PG V + Sbjct: 2207 GEPGETGP----PGRGLTGPTGA-------VGLPGPPGPSGLVGPQGSPGLPGQVGETGK 2255 Query: 137 PGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-AFAGIP 195 PGA PG+ G G +PG+ PG LPG P G +P G G A G+P Sbjct: 2256 PGA---PGRDGASGKDGDRGSPGVPGS--PG---LPG-PVGPKGEPGPTGAPGQAVVGLP 2306 Query: 196 GVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV 255 G G PG G + P G GLP GP G G AG+AG P G Sbjct: 2307 GAKGEKGA-PGGLAGDLVGEPGAKGDRGLP----------GPRGEKGEAGRAGEPGDPGE 2355 Query: 256 GPQAAAAAAAKAAAKFGAGAAGVL-----PGV-GGAGVPGVPGAIPGIGGIAG------- 302 Q A G G G PGV G G+PG+PGA PG+ G G Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA-PGVVGFPGQTGPRGE 2414 Query: 303 VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-------GVPGVGVPGA- 354 +G P + A + G L P GP PG VG PGA G PGVG+PG Sbjct: 2415 MGQPGPSGERGLAGPPGREGIPGPLGPPGP---PGSVGPPGASGLKGDKGDPGVGLPGPR 2471 Query: 355 ---GIPVVPGA-GIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGF 409 G P + G G PG P G+ P + + G+ G G +G G Sbjct: 2472 GERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG- 2530 Query: 410 PGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGV 469 P G G G G+ G G G G PG + GL PG+ G Sbjct: 2531 PRGAKGDMGERGPRGLDGDKGPRGDNGDPG----DKGSKGEPGDKGSAGL-PGLRGLLGP 2585 Query: 470 GVAPGVGVAPGVGLAPGVGVAPGV-GVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRA 528 PG PG +PG PG+ G VG +GP G+ + ++ Sbjct: 2586 QGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLKG----------ERGVKG 2632 Query: 529 AAGLGA--GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG--ALAAAKAAKYGAA 584 A GL G G G PGL AG G GVPG PG L K + Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGL---AGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDG 2689 Query: 585 VPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVP 644 PG G G G G PG GP+ +A G G GL G G G P Sbjct: 2690 QPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG-QKGERGPP 2748 Query: 645 G--VGGLGGIPPAAAAKAAKYGVAARPG 670 G V G G+P A + G RPG Sbjct: 2749 GERVVGAPGVPGAPGER----GEQGRPG 2772 Score = 141 bits (355), Expect = 2e-33 Identities = 211/691 (30%), Positives = 250/691 (36%), Gaps = 117/691 (16%) Query: 26 PGGVPG--AIPG--GVPGGVFYPGAGLGALGG-GALGPGGKPLKPVPGGLAGAGLGAGLG 80 P G PG + G G PG PG LG G G G G+P KP GL G G G Sbjct: 1995 PIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEA 2054 Query: 81 AFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAG 140 P K + G G PG+ G P P V +PG G Sbjct: 2055 GRPGER------------GERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPG 2102 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGP 199 + + P GL G G + P G +PG+ G +P G G G+PG Sbjct: 2103 LSGEQGPP-GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG-EPGPRGQDGN-PGLPGERG 2159 Query: 200 FGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVGPQA 259 GP+ L P P GG+G P GP G G AG AG PQ Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDP----------GPPGAPGLAGPAG--------PQG 2201 Query: 260 AAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--------AIPGIGGIAG-VGTPAAAA 310 + + + G G+ G G+PG PG PG+ G G G P A Sbjct: 2202 PSGLKGEPG-ETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260 Query: 311 AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG----AGVPG---VGVPGA-GIPVVPG- 361 A+ K G+ VPG PG PG VG G G PG VG+PGA G PG Sbjct: 2261 RDGASGKDGDRGSPG--VPGSPGL-PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGG 2317 Query: 362 -----AGIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGF-GV 414 G PGA G+ P A +A + G G G P G GF G GV Sbjct: 2318 LAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP----GPKGFKGDPGV 2373 Query: 415 GVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPG 474 GV G PG G PGV G G+ G+PG PGV PG G Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPG--------------------APGVVGFPGQTGPRG 2413 Query: 475 VGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 534 PG G+ PG PG PG PG V S K G Sbjct: 2414 EMGQPGPSGERGLAGPPGREGIPGPLGPPG-PPGSVGPPGASGLK-------GDKGDPGV 2465 Query: 535 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPG--------ALAAAKAAKYGAAV- 585 G+PG G PG+ G PG G+ G G A K K +AV Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525 Query: 586 ---PGVLGGLGALGGVGIPGGVVG-AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL 641 PG G G +G G P G+ G GP + G G+AGL GL G L Sbjct: 2526 LGPPGPRGAKGDMGERG-PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR-GLL 2583 Query: 642 GVPGVGGLGGIP--PAAAAKAAKYGVAARPG 670 G G G GIP P + K G+ G Sbjct: 2584 GPQGQPGAAGIPGDPGSPGKDGVPGIRGEKG 2614 Score = 132 bits (332), Expect = 1e-30 Identities = 209/717 (29%), Positives = 243/717 (33%), Gaps = 130/717 (18%) Query: 26 PGGVPGAIPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFP 83 P G PG +PG G PG PG+ G G G+P P G G GL P Sbjct: 1270 PPGDPG-LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSP 1328 Query: 84 AVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPG--VGGLGVSAAPSVPGAVVPQPGAGV 141 +PG D + + G G PG +GG G P +PG PG Sbjct: 1329 G-------LPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEG----PGLPGR-KGDPGPSG 1374 Query: 142 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVK-PKAPGVGGAFAGIPGV-GP 199 PG +G PG LPG + G G + P PG GG G PG+ G Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGT------AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGL 1428 Query: 200 FGGPQPGVPLGYPIK----------APKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGY 249 G P P P+G P K AP LPG G P G GP G G G G+ Sbjct: 1429 PGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGP----RGPPGAIGPKGDRGF 1484 Query: 250 PTGTG-------------VGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG---- 292 P G G + A + AK G G G G PG PG Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544 Query: 293 AIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPG-------FGP----GVVG 340 P + G G G A A + G ++PG PG GP G G Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604 Query: 341 VPG-AGVPG----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVG 395 PG +G PG G PG PV P G P KA + G R G Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664 Query: 396 VGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAA 455 V G P G G PG G G PG +G G G PG G PG + A + Sbjct: 1665 VRG-PVGEKGDQGDPGED-GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722 Query: 456 KYGLV--------PGVGVAPGVGVAPGVGVAPGVGLAPGV-GVA--------PGVGVAPG 498 G PG+ APG G PG PGV G A PG+ G Sbjct: 1723 DRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782 Query: 499 VGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGL 557 + PG GP G AA A G+PGL G+PG G+PG Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRD-----------GLPGLRGEQGLPGPSGPPGLPGK 1831 Query: 558 GVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAK 617 G PG G PG G G G G G GP A Sbjct: 1832 PGEDGKPGLNGKNGE----------PGDPGEDGRKGEKGDSGASGREGRDGPKGERGAP- 1880 Query: 618 AAAKAAQFGLVGAAGLGGL----GVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 670 G++G G GL G G G PGV G G P + G PG Sbjct: 1881 --------GILGPQGPPGLPGPVGPPGQGFPGVPG-GTGPKGDRGETGSKGEQGLPG 1928 Score = 128 bits (321), Expect = 2e-29 Identities = 210/735 (28%), Positives = 261/735 (35%), Gaps = 125/735 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G G P G+ PG G GP G + P G +G G Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGR 1620 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVPQPGAGV 141 P PG + P G D K + G G+PG G G+ AP V G V + G Sbjct: 1621 PGP--PGPVGPRG-RDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQG- 1676 Query: 142 KPGKVPGVGLPGVYPGGVLPGARFPGVGVLPG--VPTGAGVKPKA--------------- 184 PG+ G PG G PG PG V TG G + K Sbjct: 1677 DPGEDGRNGSPG--SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKG 1734 Query: 185 -PGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-------LPGGYGLPYTTGKLPYGY 235 PG+ GA G G+ F GP PG P G P ++ P PG G GK P Sbjct: 1735 DPGLPGA-PGERGIEGFRGP-PG-PQGDPGVRGPAGEKGDRGPPGLDGRSGLDGK-PGAA 1790 Query: 236 GPGGVAGAAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGV 290 GP G GAAGKAG P G+ G Q + G G PG+ G G PG Sbjct: 1791 GPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK-PGLNGKNGEPGD 1849 Query: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV- 349 PG G G A+ + GA L P GP PG VG PG G PGV Sbjct: 1850 PGED---GRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVP 1906 Query: 350 ------------------GVPG-AGIPVVPG-----------AGIPGAAVPGVVS----- 374 G+PG G+ PG AGI +A+ +V Sbjct: 1907 GGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDES 1966 Query: 375 -------PEAAAKAAAKAAKYGARPGVGVGGIP--------TYGVGAGGFPGFGVGVGGI 419 PE + + G G G P G G PG +G G Sbjct: 1967 SGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGP 2026 Query: 420 PGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAP 479 PG +G+ G G PG+ G+PG +A +A + G G G G P Sbjct: 2027 PGPSGLAGEPGKPGIPGLPG-------RAGGVGEAGRPG-ERGERGEKGERGEQGRDGPP 2078 Query: 480 GVGLAPGVGVAPGVGVA---PGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 536 G+ PG PG V+ PG G++ GP G+ A + G+ Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG-----DRGV 2133 Query: 537 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 596 PG+ G PG G PGL G+ G PG PG +GG G G Sbjct: 2134 PGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP-------RGPPGPVGGHGDPG 2186 Query: 597 GVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-GVPGVGGLGGIPPA 655 G PG AGPA + + + G G G G GL G PG GL G P Sbjct: 2187 PPGAPG---LAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVG-PQG 2242 Query: 656 AAAKAAKYGVAARPG 670 + + G +PG Sbjct: 2243 SPGLPGQVGETGKPG 2257 Score = 121 bits (303), Expect = 2e-27 Identities = 196/686 (28%), Positives = 239/686 (34%), Gaps = 85/686 (12%) Query: 23 PSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKP-VPGGLAGAGLGAGL 79 P PG G+PG+ PG P G P G G G G P +P PG G + Sbjct: 1420 PGEPGLPGLPGS-PG--PQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI 1476 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 G FPG L G + AG G+PGV G + P P + G Sbjct: 1477 GPKGDRGFPGPLGEAG----EKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGE 1532 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGA-GVKPKAPGVGGAFAGIPGVG 198 +PG+ G P V G + G + V P P GA GV+ + G G P G Sbjct: 1533 KGEPGR---PGDPAVV-GPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDP--G 1586 Query: 199 PFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTG-VGP 257 P G P P+G +A PG G P G P GP G G G+ G G GP Sbjct: 1587 PKGDPGDRGPIGLTGRAGP-PGDSGPPGEKGD-PGRPGPPGPVGPRGRDGEVGEKGDEGP 1644 Query: 258 QAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAG----VGTPAA 308 KA + GA GV VG G G PG PG G G G P Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704 Query: 309 AA----AAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV-GVPG-AGIPVVPG 361 A + + G P GP PG+ G PG G+ G G PG G P V G Sbjct: 1705 PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764 Query: 362 -AGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGI 419 AG G PG+ A G G G P G G PG G G+ Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP----GRDGLPGLR-GEQGL 1819 Query: 420 PGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA--------PGVGV 471 PG +G PG+ G PG G PG+ + + + G G + G Sbjct: 1820 PGPSGPPGLPGKPGEDGKPGLN-GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878 Query: 472 APGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGG--VAAAAKSAAKVAAKAQLRAA 529 APG+ G PG PG G GV G GP G +K + + LR Sbjct: 1879 APGILGPQGPPGLPGPVGPPGQGFP---GVPGGTGPKGDRGETGSKGEQGLPGERGLRGE 1935 Query: 530 AGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVL 589 G + L G+ + V +G F VP K PG Sbjct: 1936 PGSVPNVDRLLETAGIKASALREIVETWDESSG--SFLPVPERRRGPKGDSGEQGPPGKE 1993 Query: 590 GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGL 649 G +G G G+ G GP G GL +G G PG GL Sbjct: 1994 GPIGFPGERGLKGDRGDPGP---------------------QGPPGLALGERGPPGPSGL 2032 Query: 650 GGIP-----PAAAAKAAKYGVAARPG 670 G P P +A G A RPG Sbjct: 2033 AGEPGKPGIPGLPGRAGGVGEAGRPG 2058 Score = 120 bits (300), Expect = 6e-27 Identities = 191/621 (30%), Positives = 223/621 (35%), Gaps = 102/621 (16%) Query: 111 GLGGVPGVGG-LGVSAAPSVPGAVVPQ-----PGAGVKPGKVPGVGLPGVYPG--GVLPG 162 G G PG+ G G PG+ + PGA +PG G PG PG G+ Sbjct: 1269 GPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT-PGAPGLKGS 1327 Query: 163 ARFPGVGVLPGV--PTGAGVKPKAPG--VGGAFAGIPG----VGPFGGPQPGVPLGYPIK 214 PG PG P G +P APG +GG G+PG GP G P P PLG P Sbjct: 1328 PGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDP-- 1385 Query: 215 APKLPGGYGLPYTTGKL---------PYGYGPGGVA-GAAGKAGYPTGTGVGPQAAAAAA 264 P+ P G LP T K P G G GG+A G G G P G PQ Sbjct: 1386 GPRGPPG--LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPG--PQGPVGPP 1441 Query: 265 AKAAAKFGA--GAAGVLPG----------------VGGAGVPGVPGAIPGIGGIAGVGTP 306 K K + GA G LPG +G G G PG + G G P Sbjct: 1442 GKKGEKGDSEDGAPG-LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPP 1500 Query: 307 AAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPG 366 A + A + GA P GP G G PG G P V G + G Sbjct: 1501 GPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGR---------PGDPAVVGPAVAG 1551 Query: 367 -AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG----FGV-GVGGIP 420 G V P A + G PG+ + G P G G PG G+ G G P Sbjct: 1552 PKGEKGDVGPAGPRGATGVQGERGP-PGLVLPGDP----GPKGDPGDRGPIGLTGRAGPP 1606 Query: 421 GVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPG 480 G +G PG G PG G PG + P + + G PG PG G+ APG Sbjct: 1607 GDSGPPGEKGDPGRPGPPG-PVGPRGRDGEVGEKGDEG-PPGDPGLPGKAGERGLRGAPG 1664 Query: 481 VGLAPGVGVAPGVGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA---GI 536 V G G G +PG GP G G GA G Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD----TGPGAREKGE 1720 Query: 537 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALG 596 PG G G G+PG G+ GF PG PGV G G G Sbjct: 1721 PGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGP----------QGDPGVRGPAGEKG 1770 Query: 597 GVGIPG-----GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 651 G PG G+ G AA + AA A G G GL GL G G+PG G G Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKA--GDPGRDGLPGLR-GEQGLPGPSGPPG 1827 Query: 652 IP--PAAAAKAAKYGVAARPG 670 +P P K G PG Sbjct: 1828 LPGKPGEDGKPGLNGKNGEPG 1848 Score = 117 bits (292), Expect = 5e-26 Identities = 226/747 (30%), Positives = 263/747 (35%), Gaps = 128/747 (17%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P P G PGA PG V GG G GL G GP G P P G G GL Sbjct: 1342 PRGPKGEPGA-PGQVIGG---EGPGLPGRKGDP-GPSGPPGPRGPLGDPGPRGPPGL--- 1393 Query: 83 PAVTFPGALVPGGVADAAAAYKAAKAGAGLGGV-PGVGGL-GVSAAPSVPGAVVPQPGAG 140 PG + G D + G G GG+ PG GL G+ +P G V P G Sbjct: 1394 -----PGTAMKGDKGDRG---ERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKG 1445 Query: 141 VKPGKVPGV-GLPGVYPGGV-------LPGARFP-GVGVLPGVPTGAGVKPKA--PGVGG 189 K G GLPG PG PGA P G PG AG K + PG G Sbjct: 1446 EKGDSEDGAPGLPG-QPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAG 1504 Query: 190 AFAGIPGV-------GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAG 242 + G+PGV GP G P P G + PG G P G P GP G G Sbjct: 1505 S-RGLPGVAGRPGAKGPEGPPGPTGRQGEKGE----PGRPGDPAVVG--PAVAGPKGEKG 1557 Query: 243 AAGKAGYPTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIG 298 G AG TGV GP K G G + G AG PG G PG Sbjct: 1558 DVGPAGPRGATGVQGERGPPGLVLPG-DPGPKGDPGDRGPIGLTGRAGPPGDSGP-PGEK 1615 Query: 299 GIAG-VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVP---- 352 G G G P + + G PG PG PG G G G PGV P Sbjct: 1616 GDPGRPGPPGPVGPRGRDGEVGEKGDEGP--PGDPGL-PGKAGERGLRGAPGVRGPVGEK 1672 Query: 353 -GAGIPVVPGA-GIPGAA-------VPGVVSPEAAAKAAAKAAKYGARPG---------- 393 G P G G PG++ PG P A+ PG Sbjct: 1673 GDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGP 1732 Query: 394 VGVGGIPTYGVGAGGFPGF----------GV-GVGGIPGVAGVPGVGGVPGVGGVPGVGI 442 G G+P G G GF GV G G G G PG+ G G+ G PG Sbjct: 1733 KGDPGLPG-APGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAA- 1790 Query: 443 SPEAQAAAAAKAAKYGL--VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVG 500 P AA KA G +PG+ G+ PG PG+ PG PG+ G Sbjct: 1791 GPSGPNGAAGKAGDPGRDGLPGLRGEQGL---PGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847 Query: 501 VAPGI----GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVPGLGVGAGVP 555 PG G G + A+ + K + A LG G PGL VG PG G GVP Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF-PGVP 1906 Query: 556 GLGVGA-------------GVPGF-------GAVPGALAAAKAAKYGA-AVPGVLGGLGA 594 G G G G+PG G+VP + A A A+ ++ Sbjct: 1907 G-GTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965 Query: 595 LGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPP 654 G +P GP + K G G GL G G PG G G+ Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG----DRGDPGPQGPPGLAL 2021 Query: 655 AAAAKAAKYGVAARPGFGLSPIFPGGA 681 G+A PG P PG A Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRA 2048 Score = 97.8 bits (242), Expect = 3e-20 Identities = 148/501 (29%), Positives = 170/501 (33%), Gaps = 81/501 (16%) Query: 232 PYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGV 290 P G G G G G P TG GPQ +A + GA G G AG PG Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGT 1318 Query: 291 PGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPG-AGVPG 348 PGA PG+ G G+ P A G V GG G G PG G PG +G PG Sbjct: 1319 PGA-PGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPG 1377 Query: 349 ----VGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV 404 +G PG P G+PG A+ G PG G GGI Sbjct: 1378 PRGPLGDPGPRGP----PGLPGTAMKGDKGDRGER----------GPPGPGEGGIAPGEP 1423 Query: 405 GAGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQA 448 G G PG G G PG+ G PG G G G PG I P+ Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG-AIGPKGDR 1482 Query: 449 AAAAKAAKYGL--------------VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVG 494 + G +PGV PG A G PG G PG Sbjct: 1483 GFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG---AKGPEGPPGPTGRQGEKGEPGRP 1539 Query: 495 VAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAG 553 P V V P + GP G A A G +PG G PG G Sbjct: 1540 GDPAV-VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPG---DRG 1595 Query: 554 VPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAA 613 GL AG PG PG PG G G +G G G V G Sbjct: 1596 PIGLTGRAGPPGDSGPPGE----------KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPP 1645 Query: 614 AAAKAAAKAAQFGLVGAAGL-GGLG-VGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGF 671 KA + GL GA G+ G +G G G PG G G P ++ K G PG Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPK----GDRGEPG- 1700 Query: 672 GLSPIFPGGACLGKACGRKRK 692 P P G + G + K Sbjct: 1701 ---PPGPPGRLVDTGPGAREK 1718 Score = 91.7 bits (226), Expect = 2e-18 Identities = 155/545 (28%), Positives = 184/545 (33%), Gaps = 168/545 (30%) Query: 23 PSRPG--GVPGAI-PGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 P PG G+PG + P G PG PG + L PG K K PGGLAG +G Sbjct: 2274 PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL------PGAKGEKGAPGGLAGDLVGE-- 2325 Query: 80 GAFPAVTFPGAL----VPGGVADAAAAYKAAKAGA----GLGGVPGVGGLGVSAAPSVPG 131 PGA +PG + A +A + G G G PG G VPG Sbjct: 2326 --------PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPG 2377 Query: 132 AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG-- 189 + PG PG +GLPG LPGA PGV PG TG + PG G Sbjct: 2378 S----PGPPGPPGVKGDLGLPG------LPGA--PGVVGFPG-QTGPRGEMGQPGPSGER 2424 Query: 190 AFAGIPG----VGPFGGPQPGVPLGYP----IKAPKLPGGYGLPYTTGKL---------- 231 AG PG GP G P P +G P +K K G GLP G+ Sbjct: 2425 GLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDG 2484 Query: 232 -PYGYGPGGVAGAAGKAGYPTGTG-----------------VGPQAAAAAAAKAAAKFGA 273 P GP G+ G G G G +GP A + Sbjct: 2485 RPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPR 2544 Query: 274 GAAGVLPGVGGAGVPGVPGA-----------IPGIGGIAGV-GTPAAAAAAAAAAKAAKY 321 G G G G PG G+ +PG+ G+ G G P AA K Sbjct: 2545 GLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKD 2604 Query: 322 GAAAGLVPG-----------GPGFGPGVVGVPGA-GVPG-------VGVPGA-------- 354 G VPG GP G GV GA G+ G G PG Sbjct: 2605 G-----VPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKG 2659 Query: 355 --GIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 G P VPG +G PG G++ P+ + G + G G P G GGFPG Sbjct: 2660 EMGEPGVPGQSGAPGKE--GLIGPKGDRGFDGQPGPKGDQGEKGERGTP----GIGGFPG 2713 Query: 412 FG-------------------------------------VGVGGIPGVAGVPGVGGVPGV 434 VG G+PG G G G PG Sbjct: 2714 PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGP 2773 Query: 435 GGVPG 439 G G Sbjct: 2774 AGPRG 2778 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 144 bits (362), Expect = 4e-34 Identities = 224/750 (29%), Positives = 275/750 (36%), Gaps = 147/750 (19%) Query: 11 PGVLLLLLSILHPSRPGGVPGAIPGGVPGGVFYPGA----GLGALGGGALGPGGKPLKPV 66 PG ++ S+ +P P G+ G + G PGG G GL A G +GP G P P Sbjct: 453 PGSSVIYCSVGNPG-PQGIKGKV--GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG 509 Query: 67 PGGLAG-AGLGAGLGAFPAVTFPGALVPGGV-----ADAAAAYKAAKAGAGLGGVPG-VG 119 G G GL LG PGA P G+ A K AK + V G G Sbjct: 510 RQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKG 569 Query: 120 GLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGG---VLPGAR-FPGVGVLPGVP 175 G P PG QPG+ + G G PG PG PG + FPG P P Sbjct: 570 ERGPDGPPGFPG----QPGSHGRDGHAGEKGDPGP-PGDHEDATPGGKGFPG----PLGP 620 Query: 176 TGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP-IKAPK-LPGGYGLPYTTG-KLP 232 G PG+G F G PG PGVP G+P ++ P L G G + P Sbjct: 621 PGKAGPVGPPGLG--FPGPPGERG----HPGVP-GHPGVRGPDGLKGQKGDTISCNVTYP 673 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 +GP G G G G+P GPQ A + K G G A +PG PG Sbjct: 674 GRHGPPGFDGPPGPKGFP-----GPQGAPGLSGSDGHKGRPGTPGT------AEIPGPPG 722 Query: 293 -----AIPGIGGIAG---VGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG- 343 PG GG G VG P + + +PG P FG +G PG Sbjct: 723 FRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKG--------IPGDPAFGH--LGPPGK 772 Query: 344 ---AGVPGVGVPGAGIPVVPGA----GIPG-------------AAVPGVVSPEAAAKAAA 383 +GVPG+ P G P PGA GIPG A PGV P Sbjct: 773 RGLSGVPGIKGP-RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG------ 825 Query: 384 KAAKYGARPGV-GVGGIPTYGVGAGGFPGFG----------VGVGGIPGVAGVPGVGGVP 432 + + GA PG+ G G+P Y G G G G+ G+PG+ G PG G P Sbjct: 826 HSCERGA-PGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPP 884 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 492 G+ G+PG + GL PG PG PG PG PG G Sbjct: 885 GLPGIPG-PFGDDGLPGPPGPKGPRGL-PGFPGFPGERGKPGAEGCPGAKGEPGEKGMSG 942 Query: 493 VGVAPGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGA----GIPGLGVGVGVPG 547 + G+ A G IGP G ++A +Q G G PG G PG Sbjct: 943 LPGDRGLRGAKGAIGPPG------DEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPG 996 Query: 548 LGVGAGVPGL----GVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGV 598 + G PG G G PG PG + + PG+ G G G Sbjct: 997 MQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSP 1056 Query: 599 GIPG--GVVGA--------------GPAAAAAAAKAAAKAAQFGLVGAAGLGGL--GVGG 640 G PG G+ GA GP + FG G GL G+ G Sbjct: 1057 GPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGS 1116 Query: 641 LGVPGVGGLGGIPPAAAAKAAKYGVAARPG 670 G PG G G PP G+ +PG Sbjct: 1117 PGRPGPPGSSG-PPGCPGDHGMPGLRGQPG 1145 Score = 138 bits (347), Expect = 2e-32 Identities = 240/827 (29%), Positives = 288/827 (34%), Gaps = 211/827 (25%) Query: 28 GVPGAI-------PGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAG 78 G PGA P GVPG +PG L + G G GP GKP G++G G Sbjct: 98 GPPGAAGDKGDKGPTGVPG---FPG--LDGIPGHPGPPGPRGKP------GMSGHNGSRG 146 Query: 79 LGAFPAVTFPGALVPGG----------------VADAAAAYKAAKAGAGLGGVPGVGGLG 122 FP GAL PGG + A + + GL G+PG G G Sbjct: 147 DPGFPGGR--GALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAG 204 Query: 123 VSAAPS----VPGAVVP-----------QPGAGVK-----PGKVPGVGLPG--------- 153 A P+ PG V P PG GVK PG+V G PG Sbjct: 205 GPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPD 264 Query: 154 --VYPGGVLPGAR-FPGVGVLPGVP-----TGAGVK--------------------PKAP 185 +Y G G + PG+ LPG P +G G K P P Sbjct: 265 FCLYKGE--KGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFP 322 Query: 186 GVGG--AFAGIPG----VGPFGGP-------QPGVPLGYPIKAPKLPGGYGLPYTTGKLP 232 G+ G G PG +GP G P PGV + P+ PG G P G+ Sbjct: 323 GLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETG 382 Query: 233 YGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGG-AGVPGVP 291 GP G G G+ G +GP G G LPG+ G AG+PG P Sbjct: 383 -DVGPPGPPGLLGRPGEACAGMIGPPGPQ------------GFPG-LPGLPGEAGIPGRP 428 Query: 292 GAIPGIGGIAG-VGTPAAAAAAAAAAKAAKYGAAA--------GLV--PGGPG------- 333 + PG G G G P A + Y + G V PGG G Sbjct: 429 DSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGN 488 Query: 334 -----FGPGVVGVPG-AGVPG-------VGVPG----AGIPVVPGA----GIPG----AA 368 PG +G PG G+PG +G+PG G P PGA G+PG + Sbjct: 489 EGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASG 548 Query: 369 VPG--------VVS----------PEAAAKAAAKAAKYGARPGVGVGGIP-------TYG 403 PG VVS P+ + +G G G P Sbjct: 549 PPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDAT 608 Query: 404 VGAGGFPGFGVGVGGIPGVAGVPGVG--GVPGVGGVPGVGISPEAQAAAAAKAAKYGLV- 460 G GFPG +G G G G PG+G G PG G PGV P + K K + Sbjct: 609 PGGKGFPG-PLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTIS 667 Query: 461 -----PGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAA 514 PG PG PG PG APG+ + G PG G A GP G Sbjct: 668 CNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDM 727 Query: 515 KSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGV--GAGVPGLGVGAGVPGFGAVPGA 572 K G PG+ G+PG G PG +GVPG P Sbjct: 728 GDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG-PRG 786 Query: 573 LAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAG 632 A+ A +PG LG G G G G GP + A Q GL G G Sbjct: 787 DPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPG 846 Query: 633 LGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G GG G PG G PP A G+ RPG P PG Sbjct: 847 SPG-APGGKGQPGDVG----PPGPAGMKGLPGLPGRPGAHGPPGLPG 888 Score = 130 bits (326), Expect = 5e-30 Identities = 229/784 (29%), Positives = 267/784 (34%), Gaps = 178/784 (22%) Query: 22 HPSRPGGVPGA--IPG--GVPGGVFYPGAGLGALGGGALGPGGKPLKP-------VPGGL 70 H RPG PG IPG G G + PG G G G +GP G P P +PG Sbjct: 705 HKGRPG-TPGTAEIPGPPGFRGDMGDPGFG-GEKGSSPVGPPGPPGSPGVNGQKGIPGDP 762 Query: 71 AGAGLGA----GLGAFPAVT-------FPGALVPGGVAD--AAAAYKAAKAGAGLGGVPG 117 A LG GL P + PGA P G+ K + AG GVPG Sbjct: 763 AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPG 822 Query: 118 VGGLGVS-AAPSVPGAVVPQPGAGVKPGKVPGVGLPG-VYPGGVLPGARFPGVGVLPGVP 175 G AP +PG PG PG G G PG V P G PG LPG P Sbjct: 823 PPGHSCERGAPGIPGQP-GLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG---LPGRP 878 Query: 176 TGAGVKPKAPGVGGAFA--GIPGVGPFGGPQ--PGVPLGYPIKAPKLPGGYGLPYTTGK- 230 GA P PG+ G F G+PG GP+ PG P G+P + K PG G P G+ Sbjct: 879 -GAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFP-GFPGERGK-PGAEGCPGAKGEP 935 Query: 231 -------LPYGYGPGGVAGAAGKAGYPTGTGV-------------GPQAAAAAAAKAAAK 270 LP G G+ GA G G P G GP + K Sbjct: 936 GEKGMSGLP---GDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDK 992 Query: 271 -------------------FGAGAAGVLPGVGGAGVPGVPGA--------IPGIGGIAGV 303 F G G G G PG PG+ PG+ G G Sbjct: 993 GTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGE 1052 Query: 304 -GTPA----AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-------AGVPGV-- 349 G+P + A K K A+ P GP PG G PG G+PG+ Sbjct: 1053 PGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQG 1112 Query: 350 --------GVPGA-GIPVVPG-------------------------AGIPGAAVPGVVSP 375 G PG+ G P PG GIPG PG+ P Sbjct: 1113 PRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGP--PGIKGP 1170 Query: 376 EAAAKAAAKAAKYGARPGVGVGGIPTYGV-GAGGFPGFGVGVGGIPGVAGV--PGVGGVP 432 + G + G G+ G G G PG G G PG G+ PG G Sbjct: 1171 SGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK-GERGDPGSPGISPPGPRGKK 1229 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPG----VG 488 G G PG P A A +A K PG G G APG PG + Sbjct: 1230 GPPGPPGSS-GPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLR 1288 Query: 489 VAPGVGVAPGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA-GIPGLGVGVGVP 546 PG PG PG GP G K K + G G PG G+P Sbjct: 1289 GEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLP 1348 Query: 547 GLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVG 606 G PG G+PG PG A +PG G G G +G+PG Sbjct: 1349 G------PPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP 1402 Query: 607 AGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVA 666 +GP G G GL G GV GV G G PP + G Sbjct: 1403 SGP----------------GCKGEPGLD----GRRGVDGVPGSPG-PPGRKGDTGEDGYP 1441 Query: 667 ARPG 670 PG Sbjct: 1442 GGPG 1445 Score = 124 bits (312), Expect = 2e-28 Identities = 198/658 (30%), Positives = 228/658 (34%), Gaps = 120/658 (18%) Query: 23 PSRPG--GVPGAIPG-GVPGGVFYPG-AGLGALGG-----GALGPGGKPLKPVPGGLAGA 73 P PG G PGA G G PG V PG AG+ L G GA GP G P +PG Sbjct: 839 PGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP--GIPGPFGDD 896 Query: 74 GLGA--------GLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVS 124 GL GL FP FPG G A+ K G+ G+PG GL G Sbjct: 897 GLPGPPGPKGPRGLPGFPG--FPGERGKPG-AEGCPGAKGEPGEKGMSGLPGDRGLRGAK 953 Query: 125 AAPSVPG-----AVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAG 179 A PG A++ Q G +PG G PG PG + G Sbjct: 954 GAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQ------------GRR 1001 Query: 180 VKPKAPGVGGAFAGIPGV----GPFGGPQPGVPLGYP--IKAPKLPGGYGLPYTTGKLPY 233 +P G G G PG GP G P P G I P LPG G P + G P Sbjct: 1002 GEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG--PP 1059 Query: 234 GY-GPGGVAGAAGKAGYPTGT--GVGPQAAAAAAAKAAAKFGAGAAGVLPGV----GGAG 286 G+ G G G G G P GP+ + FGA LPG+ G G Sbjct: 1060 GFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPG-CPGHFGASGEQGLPGIQGPRGSPG 1118 Query: 287 VPGVPGA-----IPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVG 340 PG PG+ PG G+ G+ G P G GP PG+ G Sbjct: 1119 RPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNG 1178 Query: 341 VPG---------------AGVPG-VGVPGA----GIPVVPGAGIPGA-------AVPGVV 373 + G G PG VG+PG G P PG PG PG Sbjct: 1179 LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSS 1238 Query: 374 SPEAAAKAAAKAAKYGARPGV-------GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP 426 P A A +A K PG G G P G G PG + G PG G+P Sbjct: 1239 GPPGPAGATGRAPKDIPDPGPPGDQGPPGPDG-PRGAPGPPGLPGSVDLLRGEPGDCGLP 1297 Query: 427 GVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVP----GVGVAPGVGVAPGVGVAPGVG 482 G G PG G PG P K P G PG PG G Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPT 1357 Query: 483 LAPGVGVAPGVGV-------APGVGVAPGI-GPGGVAAAAKSAAKVAAKAQLRAAAGLGA 534 PG PG PG+ APG+ GP G +R +G G Sbjct: 1358 GLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGL----------PGMRGPSGPGC 1407 Query: 535 -GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGG 591 G PGL GV G+ G PG G G+ PG PG LGG Sbjct: 1408 KGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGPGYLGG 1465 Score = 95.9 bits (237), Expect = 1e-19 Identities = 143/491 (29%), Positives = 173/491 (35%), Gaps = 106/491 (21%) Query: 197 VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGVG 256 +GP GG V P K G G P GP G G G G P G Sbjct: 44 IGPCGGRDCSVCHCVPEK-----GSRGPP----------GPPGPQGPIGPLGAP-----G 83 Query: 257 PQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGV-GTPAAAAAAA 313 P + + GAAG G GVPG PG IPG G G G P + Sbjct: 84 PIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNG 143 Query: 314 AAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV 373 + G L PGGP PG G G V +G AV G+ Sbjct: 144 SRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILG-----------------AVKGI- 185 Query: 374 SPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPG 433 G R G+ G+P GAGG P G G PG+ G PG G PG Sbjct: 186 --------------QGDRGDPGLPGLPG-SWGAGG-PAGPTGYPGEPGLVGPPGQPGRPG 229 Query: 434 VGGVPGVGISPEAQAAAAAKAAKYGLV-PGVGVAP----------GVGVAPGVGVAPGVG 482 + G PGVG+ + Q + + G P + V P G+ PG+ PG Sbjct: 230 LKGNPGVGV--KGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPG-- 285 Query: 483 LAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVG 542 PG G+G G+ GP G + S K +L GL G PGL Sbjct: 286 -PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGEL----GL-VGDPGLFGL 339 Query: 543 VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG-AAVPGVLGGLGALGGVGIP 601 +G G G PG PG L G PG G G G VG P Sbjct: 340 IGPKGDPGNRGHPG------------PPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPP 387 Query: 602 G--GVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAK 659 G G++G A A G++G G G G G+PG G+ G P +A K Sbjct: 388 GPPGLLGRPGEACA------------GMIGPPGPQGF-PGLPGLPGEAGIPGRPDSAPGK 434 Query: 660 AAKYGVAARPG 670 K G PG Sbjct: 435 PGKPGSPGLPG 445 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 140 bits (354), Expect = 3e-33 Identities = 213/742 (28%), Positives = 266/742 (35%), Gaps = 123/742 (16%) Query: 1 MAGLTAAAPRPGVLLLLLSILHPSRPG---GVPGAIPGGVPGGVFYPGA-GLGALGGGAL 56 MAG A AP +LLLLL L + G+PG P G PG PG G+ G Sbjct: 1 MAGPRACAPL--LLLLLLGELLAAAGAQRVGLPG--PPGPPGPPGKPGQDGID----GEA 52 Query: 57 GPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVP 116 GP G P P P G G G P + L + G G P Sbjct: 53 GPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPP 112 Query: 117 GVGGLGVSAAPSVPGAVVPQPGAGVK----PGKVPGV----------GLPGVYPGGV--- 159 G+GG G+ P G P G G++ P +PG+ G PGV P G Sbjct: 113 GLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDL 172 Query: 160 -LPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPLGYP----IK 214 P PG PG+P G G G + G G P P P G P ++ Sbjct: 173 QCPSICPPGPPGPPGMPGFKG----PTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQ 228 Query: 215 APK----LPGGYGLPYTTGKLPYGY-GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAA 269 P+ LPG G P G P G+ GP G+ GA GKAG GP+ Sbjct: 229 GPRGLRGLPGPLGPPGDRG--PIGFRGPPGIPGAPGKAG--DRGERGPEGFRGPKGDLGR 284 Query: 270 KFGAGAAGVLPGVGGAGVPGVPG-----AIPGIGGIAGV-------------GTPAAAAA 311 G GV G +G PG+PG +PG+ G G G P Sbjct: 285 PGPKGTPGV---AGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGR 341 Query: 312 AAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPG 371 A + + + G A L GP PGV G AG+PG AG G+A G Sbjct: 342 AGSKGEKGERGRAGELGEAGPSGEPGVPG--DAGMPGER---------GEAGHRGSA--G 388 Query: 372 VVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGV 431 + P+ A G + +G G+P G G G VG G G AG G G+ Sbjct: 389 ALGPQGPPGAPGVRGFQGQKGSMGDPGLP----GPQGLRG-DVGDRGPGGAAGPKGDQGI 443 Query: 432 PGVGGVPG--VGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGV 489 G G+PG + P ++ G + G G GV PG G+ Sbjct: 444 AGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG-TQGPNGTSGVQGVPGPPGPLGLQG 502 Query: 490 APGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAG--LGAGIPGLGVGVGVPG 547 PGV PG+ PG+ PG K A++ ++R G + I L + P Sbjct: 503 VPGV---PGITGKPGV-PG----------KEASEQRIRELCGGMISEQIAQLAAHLRKPL 548 Query: 548 LGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGA 607 G PG AG PG PG++ A PG G G LG G G Sbjct: 549 APGSIGRPG---PAGPPGPPGPPGSIGHPGA----RGPPGYRGPTGELGDPGPRGNQGDR 601 Query: 608 GPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGL-GVPGVGGLGGIPPAAAAKAAKYGVA 666 G AA A + Q G G G+ G G G PG G PP G Sbjct: 602 GDKGAAGAGLDGPEGDQ-GPQGPQGVPGTSKDGQDGAPGEPG----PPGDPGLPGAIGAQ 656 Query: 667 ARPGFGLSPIFPGGACLGKACG 688 PG I AC G G Sbjct: 657 GTPG-----ICDTSACQGAVLG 673 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 140 bits (352), Expect = 5e-33 Identities = 223/719 (31%), Positives = 263/719 (36%), Gaps = 109/719 (15%) Query: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKP-LKPVPG--GLAGA-GLGAGLGAFP 83 G+PGA PG G + PG G GP G P L+ VPG GL G GL A LG+ P Sbjct: 888 GMPGA-PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLP 946 Query: 84 AVTFPGALVPGGVADAAAA---YKAAKAGAGLGGVPGVGGLGVSAAPSV----PGAVVPQ 136 + G A Y K G G+PGV GL A + P A + Sbjct: 947 IEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEAR 1006 Query: 137 -PGAGVKPGKVPGVGLPGVYPGGVLPGARF----PGVGVLPGVPTGAGVKPKAPGVGGAF 191 + PG V GLPG PG LPG R PG+ PG P G PG GA Sbjct: 1007 GDNSEGDPGCVGSPGLPGP-PG--LPGQRGEEGPPGMRGSPGPPGPIG----PPGFPGA- 1058 Query: 192 AGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK--LPYGYGPGGVAGAAGKAGY 249 G PG+ G + L P PG G P TG LP G G G+AG+ G Sbjct: 1059 VGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGE 1118 Query: 250 PTGTGV----GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGT 305 P G GP A + + +G G G G PG PG PG G VG+ Sbjct: 1119 PGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP-PGFPG--KVGS 1175 Query: 306 PAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPG-AGVPGV----GVPGAGIPVVP 360 P A G + +PG PG PG G+ G AG+ G+ G PG Sbjct: 1176 PGPPGPQAEKGSEGIRGPSG--LPGSPG-PPGPPGIQGPAGLDGLDGKDGKPGL------ 1226 Query: 361 GAGIPG-AAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIP--TYGVGAGGFPGF--GVG 415 G PG A PG++ P G + G G P T GA G PG G Sbjct: 1227 -RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQG 1285 Query: 416 VGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGV 475 G PG G PG G PG G+ VG+ + A G+ PG PG Sbjct: 1286 RPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGER---------GLAGLPGQPGPPGH 1336 Query: 476 GVAPGVGLAPGVGVAPGVGVAPG-VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGA 534 PG PG A G PG G GP G AA + K RA G Sbjct: 1337 PGPPG---EPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKG--RAGMPGGP 1391 Query: 535 GIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA-------------------- 574 G G VG PG G PG +G PG VPG++ Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451 Query: 575 AAKAAKYG---------AAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQF 625 + A Y AA PG G G G G PG P + + + Q Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-----APGSPGLPGQIGREGRQ- 1505 Query: 626 GLVGAAGLGGL----GVGGLGVPGVGGLGGIP-PAAAAKAAKYGVAARPGFGLSPIFPG 679 GL G GL G G G+G+ G GL G P P K G G P PG Sbjct: 1506 GLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPG 1564 Score = 136 bits (342), Expect = 7e-32 Identities = 225/777 (28%), Positives = 269/777 (34%), Gaps = 146/777 (18%) Query: 26 PGGVPG----AIPG--GVPGGVFYPGAGLGALG-GGALGPGGKPLKPVPGGLAG------ 72 P G+PG +PG G PGG P G+ G G GPGGKP KP G G Sbjct: 451 PPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVC 510 Query: 73 AGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGA 132 L G F V PG P G A+ G+ G+ G G + SV GA Sbjct: 511 PTLPEGFQNF--VGLPGKPGPKGEPGDPVP---ARGDPGIQGIKGEKGEPCLSCSSVVGA 565 Query: 133 --VVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGA 190 +V GA G PG GLPG+ +PG + P G+ P PG G Sbjct: 566 QHLVSSTGASGDVGS-PGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGS---PGPPGPVGP 621 Query: 191 FAGIPGV-------------------------GPFGGP-QPGVP-LGYPIKAPKL----- 218 AGI G GP G +PG P G P K K Sbjct: 622 -AGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGL 680 Query: 219 ---------PGGYGLPYTTGKLPYGYGPGGVAGAAGKAGYP-TGTGVGPQAAAAAAAKAA 268 PG G P TTG+ P G GV G AG G G P A Sbjct: 681 KGQKGDAGNPGDPGTPGTTGR-PGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAG 739 Query: 269 AKFGAGAAGVL--PGVGGAGVPGVPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAG 326 G G GVG G PG PG +PG+ G G+ G Sbjct: 740 RPGQPGPKGEQGPEGVGRPGKPGQPG-LPGVQGPPGLKGVQGEPGPPGRGVQGPQGE--- 795 Query: 327 LVPGGPGFGPGVVGVPGA-GVPG-VGVPGA-GIPVVPGA----GIPGAAV---PGVVSPE 376 PG PG PG+ G+PG G PG G GA G P V GA G PGA+V PG + Sbjct: 796 --PGAPGL-PGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQ 852 Query: 377 AAAKAAAKAAKYGARPGVGVGG---IPTYG----VGAGGFPGFGVGVGGIPGVAGVPGVG 429 + G R G G P+ G G G PG +G PG G PG+ Sbjct: 853 GQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIP 912 Query: 430 GVPGVGGVPGVGISP--EAQAAAAAKAAKYGLVP---------------GVGVAPGVGVA 472 G PG GVPG+ P A+ G +P G PG V Sbjct: 913 GPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVE 972 Query: 473 PGVGVAPGVGLAPGVGVA-----------------------PGVGVAPGVGVAPGI---- 505 G G+ PG+ PG +PG+ PG+ Sbjct: 973 KGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQR 1032 Query: 506 ---GPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAG 562 GP G+ + + A G G+PGL G+ GL G PG G Sbjct: 1033 GEEGPPGMRGSPGPPGPIGPPG-FPGAVG-SPGLPGLQGERGLTGLTGDKGEPGPPGQPG 1090 Query: 563 VPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKA 622 PG PG L K + G G G G G+PG AGP + + Sbjct: 1091 YPGATGPPG-LPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEK 1149 Query: 623 AQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPGFGLSPIFPG 679 G G G G G G PG G G PP A+ G+ G SP PG Sbjct: 1150 GDQGFQGQPGFPG-PPGPPGFPGKVGSPG-PPGPQAEKGSEGIRGPSGLPGSPGPPG 1204 Score = 119 bits (299), Expect = 7e-27 Identities = 208/710 (29%), Positives = 248/710 (34%), Gaps = 130/710 (18%) Query: 54 GALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTFPGALV-PGGVADAAAAYKAAKAG--- 109 GALGP G P G G G+ P PG PG + + G Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPGK--PGRDGRPGEICVIGPKGQKGDPGFVG 441 Query: 110 -AGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPG-------VGLPGVYPGGVLP 161 GL G PG GL P PG + PG PG PG G+PG G P Sbjct: 442 PEGLAGEPGPPGL-----PGPPG--IGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494 Query: 162 GARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPG 220 G PGV G P V P P F G+PG GP G P G P+ A PG Sbjct: 495 GK--PGVKGEKGDP--CEVCPTLPEGFQNFVGLPGKPGPKGEP------GDPVPARGDPG 544 Query: 221 GYGLPYTTGK----LPYGYGPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAA 276 G+ G+ G + + G +G G G A K G Sbjct: 545 IQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLK---GEK 601 Query: 277 GVLPGVGGAGVPGVPGAIPGIGGIAGV-GTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG 335 G G AG PG PG + G GI G G P A + + A +P GP Sbjct: 602 GNFGEAGPAGSPGPPGPV-GPAGIKGAKGEPCEPCPALSNLQDGDVRVVA--LP-GPSGE 657 Query: 336 PGVVGVPGAGVPGV-------GVPG----AGIPVVPG----AGIPG-AAVPGVVSP---- 375 G G PG G+PG G+ G AG P PG G PG + PGV P Sbjct: 658 KGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPK 717 Query: 376 -------EAAAKAAAKAAKYGARPGV--GVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVP 426 A RPG G GVG G P G G+PGV G P Sbjct: 718 GEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKP----GQPGLPGVQGPP 773 Query: 427 GVGGVPGVGGVPGVGI-SPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 485 G+ GV G G PG G+ P+ + A GL PG PG G +PGV A Sbjct: 774 GLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGL-PGPRGPPGPTGEKGAQGSPGVKGAT 832 Query: 486 GVGVAPGVGVA--PG-------VGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 536 G PG V+ PG G+ G G + + +Q G Sbjct: 833 GPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGA 892 Query: 537 PGLGVG----------VGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGA--- 583 PGL +G G+PG GVPGL GVPG +PG A+ G+ Sbjct: 893 PGLWMGSSWQPGPQGPPGIPGPPGPPGVPGL---QGVPGNNGLPG--QPGLTAELGSLPI 947 Query: 584 -----------------AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFG 626 A PG L G G GIP GV G A + +A + Sbjct: 948 EQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIP-GVPGLDNCAQCFLSLERPRAEEAR 1006 Query: 627 LVGAAGLGGLGVGGLGVPGVGGLGGI-----PPAAAAKAAKYGVAARPGF 671 + G G VG G+PG GL G PP G PGF Sbjct: 1007 GDNSEGDPGC-VGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGF 1055 Score = 108 bits (269), Expect = 2e-23 Identities = 168/552 (30%), Positives = 201/552 (36%), Gaps = 104/552 (18%) Query: 28 GVPGAI-PGGVPGGVFYPGAGLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGLGAFPA 84 G PG I P G PG V PG L L G G G G +P P G G Sbjct: 1045 GPPGPIGPPGFPGAVGSPG--LPGLQGERGLTGLTGDKGEPGPPGQPG------------ 1090 Query: 85 VTFPGALVPGGVADAAA--AYKAAKAGAGLGGVPGVGGLGVSAAPSVP-GAVVPQPGAGV 141 +PGA P G+ Y + G G PG GL P+ P G PQ +G Sbjct: 1091 --YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGE 1148 Query: 142 K--------------------PGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGV 180 K PGKV G PG G R P G+ PG P G+ Sbjct: 1149 KGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGI 1208 Query: 181 KPKAPGVGGAFA--GIPGV----GPFGGPQPGVPLGYPIKA--------------PKLPG 220 + A G+ G G PG+ GP G P P G+ K P PG Sbjct: 1209 QGPA-GLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPG 1267 Query: 221 GYGLPYTTGKLPYGYGPGGVAGAAGKAGYPTGTGV-GPQAAAAAAAKA--AAKFGAGAAG 277 G P G+ P GP G G G G P G GP +A K A G AG Sbjct: 1268 STGRPGAEGE-PGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAG 1326 Query: 278 VLPGVGGAGVPGVPGAIPGIGGIAG----------VGTPAAAAAAAAAAKAAKYG--AAA 325 + G G PG PG PG G AG G P AA + + G A Sbjct: 1327 LPGQPGPPGHPGPPGE-PGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRA 1385 Query: 326 GLVPGGPGFGP--GVVGVPG-AGVPG-VGVPG-AGIPVVPGAGIPGAA--------VPGV 372 G+ PGGPG G VG PG AG G G PG +G P +PG +PG+ + Sbjct: 1386 GM-PGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPG--VPGSMGDMVNYDEIKRF 1442 Query: 373 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVP 432 + E + A Y +R P A G PG G G PG G PG G+P Sbjct: 1443 IRQEIIKMFDERMAYYTSRMQ-----FPMEMAAAPGRPG-PPGKDGAPGRPGAPGSPGLP 1496 Query: 433 GVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG 492 G G G P + K K + G+ G+ PG PG G G Sbjct: 1497 GQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQ 1556 Query: 493 VGVAPGVGVAPG 504 G+ PG+ PG Sbjct: 1557 QGI-PGIPGPPG 1567 Score = 100 bits (249), Expect = 5e-21 Identities = 146/455 (32%), Positives = 176/455 (38%), Gaps = 78/455 (17%) Query: 25 RPG--GVPGAIPGGVPGGVFYPGA-GLGALGG--GALGPGGKPLKPVPGGLAGAGLGAGL 79 +PG G PG P G PG V PG G A G G GP G P P P G G AGL Sbjct: 1157 QPGFPGPPG--PPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214 Query: 80 GAFPAVTFPGALVPGGVADAAAAYKAAKAGA----GLGGVPGVGG-LGVSAAPSVPGAVV 134 PG D A G G G PG+ G G P PG+ Sbjct: 1215 DGLDGKDGK----PGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGST- 1269 Query: 135 PQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGG----- 189 +PGA +PG + G PG PG V P PG PG P AG+ A G+ G Sbjct: 1270 GRPGAEGEPGAMGPQGRPGP-PGHVGP----PGP---PGQPGPAGIS--AVGLKGDRGAT 1319 Query: 190 ---AFAGIPGV-GPFGGPQPGVPLGYPIKA-----PKLPGGYGLPYTTGKLPYGYGPGGV 240 AG+PG GP G P P G A P G YG P G P G G Sbjct: 1320 GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGD-PGAAGQKGQ 1378 Query: 241 AGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGA-GVPGVPGAIPGIGG 299 AG G+AG P G G A + G A PG G+ G+PGVPG++ + Sbjct: 1379 AGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGA---PGPSGSPGLPGVPGSMGDMVN 1435 Query: 300 IAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA-GVPGVGVPGA-GIP 357 + + Y + P PG G PG G PG PGA G P Sbjct: 1436 YDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR--PGAPGSP 1493 Query: 358 VVPGA-------GIPGA-AVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGV----G 405 +PG G+PG +PG G + +G+G G+ G Sbjct: 1494 GLPGQIGREGRQGLPGVRGLPGTK---------------GEKGDIGIGIAGENGLPGPPG 1538 Query: 406 AGGFPGFG-VGVGGIPGVAGVPGVGGVPGVGGVPG 439 G PG+G +G G G G+PG+ G PG G PG Sbjct: 1539 PQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573 Score = 92.4 bits (228), Expect = 1e-18 Identities = 137/456 (30%), Positives = 166/456 (36%), Gaps = 71/456 (15%) Query: 236 GPGGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIP 295 G G +GA G +G P TG Q K G G+ G G G PG I Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQ-----------KGEKGDGGIKGVPGKPGRDGRPGEIC 426 Query: 296 GIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFG-PGVVGVPGAGVPG-VGVPG 353 IG G P A + G +PG PG G PG G PG G PG G G Sbjct: 427 VIGPKGQKGDPGFVGPEGLAGEPGPPG-----LPGPPGIGLPGTPGDPG-GPPGPKGDKG 480 Query: 354 -AGIPVVPG-AGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPG 411 +GIP G G PG PGV + G + VG+ G P G G PG Sbjct: 481 SSGIPGKEGPGGKPGK--PGVKGEKGDPCEVCPTLPEGFQNFVGLPGKP----GPKGEPG 534 Query: 412 FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGV 471 V G PG+ G+ G G P + VG LV G + VG Sbjct: 535 DPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQ--------------HLVSSTGASGDVG- 579 Query: 472 APGVGV--APGVGLAPGVGVAPGVGVAPGVGVAPG----IGPGGV-AAAAKSAAKVAAKA 524 +PG G+ PG PG+ G G +PG +GP G+ A + A + Sbjct: 580 SPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALS 639 Query: 525 QLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAA 584 L+ +PG G PG G G+PG AG G K K A Sbjct: 640 NLQDGDVRVVALPGPSGEKGEPG-PPGFGLPGKQGKAGERGL----------KGQKGDAG 688 Query: 585 VPGVLGGLGALGGVGIPG--GVVG-AGPAAAAAAAKAAAKAAQFGLVGAAG-------LG 634 PG G G G G+ G GV G AGP A + Q + AG G Sbjct: 689 NPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKG 748 Query: 635 GLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARPG 670 G G+G PG G G+P K GV PG Sbjct: 749 EQGPEGVGRPGKPGQPGLPGVQGPPGLK-GVQGEPG 783 Score = 60.1 bits (144), Expect = 7e-09 Identities = 107/370 (28%), Positives = 134/370 (36%), Gaps = 72/370 (19%) Query: 327 LVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGIPGAAVPGVV--SPEAAAKAAAK 384 L P GP G G G+PG PG+ G GA V SP+A + A Sbjct: 330 LAPSGPKGGKGERGLPGP-------PGS-------KGEKGARGNDCVRISPDAPLQCAE- 374 Query: 385 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGV------GGVPGVGGVP 438 G + G G +G G+PG G G GG+ GV G P Sbjct: 375 ----GPKGEKGESG--------------ALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKP 416 Query: 439 GVGISPEAQAAAAAKAAK--YGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVA 496 G P K K G V G+A G PG+ PG+GL PG PG Sbjct: 417 GRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPG-PPGLPGPPGIGL-PGTPGDPGGPPG 474 Query: 497 P-----GVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIP-GLGVGVGVPGLGV 550 P G+ GPGG K K + + +P G VG+PG Sbjct: 475 PKGDKGSSGIPGKEGPGG------KPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPG 528 Query: 551 GAGVPGLGVGA----GVPGFGAVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPG-GVV 605 G PG V A G+ G G + ++ GA ++ GA G VG PG G+ Sbjct: 529 PKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGA--QHLVSSTGASGDVGSPGFGLP 586 Query: 606 GAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP--PAAAAKAAKY 663 G A K + FG G AG G G +G G+ G G P P A + Sbjct: 587 GLPGRAGVPGLK--GEKGNFGEAGPAGSPG-PPGPVGPAGIKGAKGEPCEPCPALSNLQD 643 Query: 664 G---VAARPG 670 G V A PG Sbjct: 644 GDVRVVALPG 653 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 138 bits (347), Expect = 2e-32 Identities = 197/654 (30%), Positives = 223/654 (34%), Gaps = 83/654 (12%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 959 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 1014 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 G A PG P G++ D A + GL G G GL P P V P Sbjct: 1015 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1071 Query: 138 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 197 G G +GLPG PG + P PG P G P G G AG GV Sbjct: 1072 GERGSAGTAGPIGLPG------RPGPQGP-----PG-PAGEKGAPGEKGPQGP-AGRDGV 1118 Query: 198 -GPFGGPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 GP G P P P G P I P G G G GP G+ G G G Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPG 1174 Query: 249 YPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1234 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIP 365 G P GP PG VG G GV G PG AG P PG AG+ Sbjct: 1235 PPGPRGPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVG 1284 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 G G + A A GA+ G G P G GFPG G G PG AG Sbjct: 1285 GPK--GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQ 1340 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 485 GVGG G G PG P A PG PG A G G Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGP-----PGKRGPPGAAGAEGRQGEKGAKGEA 1395 Query: 486 GVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 544 G PG G G A GP G+ + G+PG G Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--------------QGLPGAAGQDG 1441 Query: 545 VPGLGVGAGVPGLGVGAGVPGFGAVPGALA-----AAKAAKYGAAVPGVLGGLGALGGVG 599 PG G+PGL G G PG + + K +PG G GA G G Sbjct: 1442 PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG 1501 Query: 600 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 653 IPG GP G G AG G G+PG G G P Sbjct: 1502 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG----QKGDSGLPGPPGSPGPP 1551 Score = 136 bits (342), Expect = 7e-32 Identities = 220/742 (29%), Positives = 257/742 (34%), Gaps = 114/742 (15%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 587 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 643 Query: 70 LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPS 128 + G G P P L+ G G PG G+ GV P Sbjct: 644 MRGEDGEIGPRGLPGEAGPRGLL---------------GPRGTPGAPGQPGMAGVDGPPG 688 Query: 129 VPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPK 183 G + PQ PG + G GLPG P G + PG + P G L G+P GA P Sbjct: 689 PKGNMGPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPG 745 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYG 234 PG G +GP P P P+GYP P+ G GL + G+ P Sbjct: 746 HPGKEGQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGF 800 Query: 235 YGPGGVAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 G G+ G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 801 KGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVP 352 G G P A A A K G P GP G G G P Sbjct: 860 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919 Query: 353 GAGIPVVPGAGIP-----GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG 407 G G P PG P PG P G R G G T G G Sbjct: 920 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG-KTGPPGPG 978 Query: 408 GFPG--------FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 G G +G G PG G PG G+PG G G P Q + K GL Sbjct: 979 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ-GISGKDGPAGL 1037 Query: 460 --VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG----VGVAPGVGVAPGIGPGGVAAA 513 PG PG APG+ G PG +PG G A +G+ GP G Sbjct: 1038 RGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGP 1097 Query: 514 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 A K AG G+ VG+PG AG PG G G PG Sbjct: 1098 AGEKGAPGEKGPQGP-----AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG---EPGQ- 1148 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA--AAKAAAKAAQF-GLVGA 630 +K K PG G G +G GI GG GP K A F G G Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1208 Query: 631 AGLGGL-----------GVGGLGVPGVGGLGGI-----------PPAAAAKAAKYGVAAR 668 GL GL VG +G PG G G PP + G Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268 Query: 669 PGFGLSPIFPGGACLGKACGRK 690 PG +P PG A +G G + Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGER 1290 Score = 107 bits (268), Expect = 3e-23 Identities = 198/676 (29%), Positives = 232/676 (34%), Gaps = 109/676 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 458 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 506 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 + G G A A A +A L G PG GL Sbjct: 507 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG---------------- 550 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 +PG V G G G PG + P GV PG PTG K PG G G+PG Sbjct: 551 --RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEP 606 Query: 199 PFGGPQ-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246 G + PG+P G+ P P PG G+ G++ GP G+ G AG Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGP 662 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVG 304 G +GP+ A + G G +G G PG PG PG G+ G Sbjct: 663 RGL-----LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQ 717 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG 361 P PG GP PG+ G+PGA P G PG G G Sbjct: 718 GPIGP-------------------PGEKGPQGKPGLAGLPGADGP-PGHPGKEGQSGEKG 757 Query: 362 A-GIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY--GVGAGGFPGFGVGVG 417 A G PG P G P A G++ G G P + +G G G VG Sbjct: 758 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG-EVGQI 816 Query: 418 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 477 G G G G G G G PG P QA K VPG+ PG G Sbjct: 817 GPRGEDGPEGPKGRAGPTGDPG----PSGQAGEKGKLG----VPGLPGYPGRQGPKGSTG 868 Query: 478 APGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 536 PG A G A GV PG G GP G A K K G G Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK-----GTSGGDGP 923 Query: 537 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYGAAVPGVL--- 589 PG G G G PG G PG +PG K G PG + Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983 Query: 590 -GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 648 G G G +G G GP AA K G G G+ G G G+ G G Sbjct: 984 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD-GPAGLRGFPG 1042 Query: 649 LGGIPPAAAAKAAKYG 664 G+P A A K G Sbjct: 1043 ERGLPGAQGAPGLKGG 1058 Score = 95.9 bits (237), Expect = 1e-19 Identities = 146/507 (28%), Positives = 180/507 (35%), Gaps = 90/507 (17%) Query: 182 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 237 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 455 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 513 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G PT + Q A A A A+ + G PG + Sbjct: 514 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 549 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 353 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 607 Query: 354 A-------GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 A G+P +PG G P+ G +G G+P G Sbjct: 608 AKGDRGFDGLPGLPG----DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP----GE 659 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 466 G G +G G PG G PG+ GV G G G + P+ + PG Sbjct: 660 AGPRGL-LGPRGTPGAPGQPGMAGVDGPPGPKG-NMGPQGEPGP----------PGQQGN 707 Query: 467 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 526 PG PG G G PG+ PG PG PG + + A Sbjct: 708 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGA-------- 758 Query: 527 RAAAGLGAGIPGLGVGVGVPG-LGV-GA-GVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 583 G PG +G PG GV GA GV GL G G PG K Sbjct: 759 -------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG-------FKGDM 804 Query: 584 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 643 + G G +G +G G G G A + +A + G +G GL G G G Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY-PGRQGP 863 Query: 644 PGVGGLGGIPPAAAAKAAKYGVAARPG 670 G G G P A K A+ GVA +PG Sbjct: 864 KGSTGFPGFPGANGEKGAR-GVAGKPG 889 Score = 92.0 bits (227), Expect = 2e-18 Identities = 162/522 (31%), Positives = 181/522 (34%), Gaps = 120/522 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 PG G P G PG V PG A G GP G P +P P G G G Sbjct: 1053 PGLKGGEGPQGPPGPVGSPGERGSA---GTAGPIGLPGRPGPQGPPGPAGEKGA------ 1103 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGAG 140 PG P G A D AG G PG G G P G+ + G Sbjct: 1104 --PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1161 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVPTGAGVK--PKAPGVG 188 PG VG PG+ G PG R G PG P G++ P PG Sbjct: 1162 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G + +GP G P P P G P A G G P + G + G G G G AG G Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPG 1276 Query: 249 YPTGTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV----------- 278 P GVG P AA AK K G G Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336 Query: 279 ---LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGA 323 GVGG G PG PG PG G AG P AA A K AK A Sbjct: 1337 PAGQDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395 Query: 324 AAGLVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA- 362 A PG G GP G G PG G+PG G+PGA G P +PG Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455 Query: 363 GIPGA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFP 410 G PG+ + G++ P E K PG G GGIP +G G P Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515 Query: 411 GF--------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G G G G+ G PG G PG I P Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1557 Score = 61.2 bits (147), Expect = 3e-09 Identities = 89/310 (28%), Positives = 107/310 (34%), Gaps = 31/310 (10%) Query: 392 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGV------- 440 PG+ V G P AG G PG G G PG G PG G+PG G+PG Sbjct: 448 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 507 Query: 441 -----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 495 G + +A +A ++ +A + PG G+ PG PG Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIA--LRGPPG---PMGLTGRPGPVGGPGSSG 562 Query: 496 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 554 A G PG GP GV K + R A G G+PG G G G+ Sbjct: 563 AKGESGDPGPQGPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGFDGLPGL 620 Query: 555 PGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 609 PG G G PG + +PG G G LG G PG G Sbjct: 621 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680 Query: 610 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARP 669 A G G G G G G+PG G G PP K G+A P Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKPGLAGLP 738 Query: 670 GFGLSPIFPG 679 G P PG Sbjct: 739 GADGPPGHPG 748 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 138 bits (347), Expect = 2e-32 Identities = 197/654 (30%), Positives = 223/654 (34%), Gaps = 83/654 (12%) Query: 22 HPSRPG--GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGL 79 HP + G G G PGGV P G G +G G P P P G GL Sbjct: 908 HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETG--PIGERGHPGPPGPPG--EQGLPGAA 963 Query: 80 GAFPAVTFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQP 137 G A PG P G++ D A + GL G G GL P P V P Sbjct: 964 GKEGAKGDPG---PQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSP 1020 Query: 138 GAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGV 197 G G +GLPG PG + P PG P G P G G AG GV Sbjct: 1021 GERGSAGTAGPIGLPG------RPGPQGP-----PG-PAGEKGAPGEKGPQGP-AGRDGV 1067 Query: 198 -GPFGGPQPGVPLGYP--------IKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 GP G P P P G P I P G G G GP G+ G G G Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP----GPPGLQGPVGAPG 1123 Query: 249 YPTGTGV-GPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGIGGIAGVGTPA 307 G G GP+ + + G G +G G+PG PG G + +G P Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1183 Query: 308 AAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG-AGIP 365 G P GP PG VG G GV G PG AG P PG AG+ Sbjct: 1184 PPGPRGPQGPNGADG------PQGP---PGSVGSVG-GVGEKGEPGEAGNPGPPGEAGVG 1233 Query: 366 GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGV 425 G G + A A GA+ G G P G GFPG G G PG AG Sbjct: 1234 GPK--GERGEKGEAGPPGAAGPPGAKGPPGDDG-PKGNPGPVGFPG-DPGPPGEPGPAGQ 1289 Query: 426 PGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAP 485 GVGG G G PG P A PG PG A G G Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGP-----PGKRGPPGAAGAEGRQGEKGAKGEA 1344 Query: 486 GVGVAPG-VGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVG 544 G PG G G A GP G+ + G+PG G Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--------------QGLPGAAGQDG 1390 Query: 545 VPGLGVGAGVPGLGVGAGVPGFGAVPGALA-----AAKAAKYGAAVPGVLGGLGALGGVG 599 PG G+PGL G G PG + + K +PG G GA G G Sbjct: 1391 PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG 1450 Query: 600 IPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIP 653 IPG GP G G AG G G+PG G G P Sbjct: 1451 IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG----QKGDSGLPGPPGSPGPP 1500 Score = 136 bits (342), Expect = 7e-32 Identities = 220/742 (29%), Positives = 257/742 (34%), Gaps = 114/742 (15%) Query: 25 RPG--GVPGAIPG-GVPGGVFYPGA-------GLGALGG-----GALGPGGKPLKPVPGG 69 +PG G PGA G G+PG PGA GL L G G GP G P P G Sbjct: 536 KPGKRGRPGADGGRGMPGE---PGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDG 592 Query: 70 LAGAGLGAGLGAFPAVTFPGALVPGGVADAAAAYKAAKAGAGLGGVPGVGGL-GVSAAPS 128 + G G P P L+ G G PG G+ GV P Sbjct: 593 MRGEDGEIGPRGLPGEAGPRGLL---------------GPRGTPGAPGQPGMAGVDGPPG 637 Query: 129 VPGAVVPQ--PGAGVKPGKVPGVGLPGVYPGGVL--PGARFP-GVGVLPGVPTGAGVKPK 183 G + PQ PG + G GLPG P G + PG + P G L G+P GA P Sbjct: 638 PKGNMGPQGEPGPPGQQGNPGPQGLPG--PQGPIGPPGEKGPQGKPGLAGLP-GADGPPG 694 Query: 184 APGVGGAFAGIPGVGPFGGPQPGVPLGYPIKAPK----LPGGYGLPYTTGK-----LPYG 234 PG G +GP P P P+GYP P+ G GL + G+ P Sbjct: 695 HPGKEGQSGEKGALGP---PGPQGPIGYP--GPRGVKGADGVRGLKGSKGEKGEDGFPGF 749 Query: 235 YGPGGVAGAAGKAGY--PTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 292 G G+ G G+ G P G GP+ A +G AG +G G+PG PG Sbjct: 750 KGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 808 Query: 293 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVP 352 G G P A A A K G P GP G G G P Sbjct: 809 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868 Query: 353 GAGIPVVPGAGIP-----GAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAG 407 G G P PG P PG P G R G G T G G Sbjct: 869 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG-KTGPPGPG 927 Query: 408 GFPG--------FGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGL 459 G G +G G PG G PG G+PG G G P Q + K GL Sbjct: 928 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQ-GISGKDGPAGL 986 Query: 460 --VPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPG----VGVAPGVGVAPGIGPGGVAAA 513 PG PG APG+ G PG +PG G A +G+ GP G Sbjct: 987 RGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGP 1046 Query: 514 AKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGAL 573 A K AG G+ VG+PG AG PG G G PG Sbjct: 1047 AGEKGAPGEKGPQGP-----AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIG---EPGQ- 1097 Query: 574 AAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAA--AAKAAAKAAQF-GLVGA 630 +K K PG G G +G GI GG GP K A F G G Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGP 1157 Query: 631 AGLGGL-----------GVGGLGVPGVGGLGGI-----------PPAAAAKAAKYGVAAR 668 GL GL VG +G PG G G PP + G Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217 Query: 669 PGFGLSPIFPGGACLGKACGRK 690 PG +P PG A +G G + Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGER 1239 Score = 107 bits (268), Expect = 3e-23 Identities = 198/676 (29%), Positives = 232/676 (34%), Gaps = 109/676 (16%) Query: 23 PSRPGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAF 82 P+ P G+ G P G+ G PG G GP G+P P GL G G Sbjct: 407 PAGPAGIMG--PPGLQGPTGPPG------DPGDRGPPGRPGLPGADGLPGP---PGTMLM 455 Query: 83 PAVTFPGALVPGGVADAAAAYKAA---KAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGA 139 + G G A A A +A L G PG GL Sbjct: 456 LPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTG---------------- 499 Query: 140 GVKPGKVPGVGLPGVYPGGVLPGARFP-GVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVG 198 +PG V G G G PG + P GV PG PTG K PG G G+PG Sbjct: 500 --RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG-PTGKPGKRGRPGADGG-RGMPGEP 555 Query: 199 PFGGPQ-----PGVP--LGY-----PIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGK 246 G + PG+P G+ P P PG G+ G++ GP G+ G AG Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGP 611 Query: 247 AGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG--AIPGIGGIAGVG 304 G +GP+ A + G G +G G PG PG PG G+ G Sbjct: 612 RGL-----LGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQ 666 Query: 305 TPAAAAAAAAAAKAAKYGAAAGLVPG--GPGFGPGVVGVPGAGVPGVGVPG-AGIPVVPG 361 P PG GP PG+ G+PGA P G PG G G Sbjct: 667 GPIGP-------------------PGEKGPQGKPGLAGLPGADGP-PGHPGKEGQSGEKG 706 Query: 362 A-GIPGAAVP-GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY--GVGAGGFPGFGVGVG 417 A G PG P G P A G++ G G P + +G G G VG Sbjct: 707 ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRG-EVGQI 765 Query: 418 GIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV 477 G G G G G G G PG P QA K VPG+ PG G Sbjct: 766 GPRGEDGPEGPKGRAGPTGDPG----PSGQAGEKGKLG----VPGLPGYPGRQGPKGSTG 817 Query: 478 APGVGLAPGVGVAPGVGVAPGV-GVAPGIGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGI 536 PG A G A GV PG G GP G A K K G G Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK-----GTSGGDGP 872 Query: 537 PGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALA----AAKAAKYGAAVPGVL--- 589 PG G G G PG G PG +PG K G PG + Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932 Query: 590 -GGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGG 648 G G G +G G GP AA K G G G+ G G G+ G G Sbjct: 933 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKD-GPAGLRGFPG 991 Query: 649 LGGIPPAAAAKAAKYG 664 G+P A A K G Sbjct: 992 ERGLPGAQGAPGLKGG 1007 Score = 95.9 bits (237), Expect = 1e-19 Identities = 146/507 (28%), Positives = 180/507 (35%), Gaps = 90/507 (17%) Query: 182 PKAPGVGGAFAGIPGV-GPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK---LPYGYGP 237 P P G PG+ GP G P G P + P LPG GLP G LP+ YG Sbjct: 404 PPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR-PGLPGADGLPGPPGTMLMLPFRYGG 462 Query: 238 GGVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPGAIPGI 297 G G PT + Q A A A A+ + G PG + Sbjct: 463 DGSKG-------PT---ISAQEAQAQAILQQARIA--------------LRGPPGPMGLT 498 Query: 298 GGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGA----GVPGVGVPG 353 G VG P ++ A + G P GP PG G PGA G+P G PG Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMP--GEPG 556 Query: 354 A-------GIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 406 A G+P +PG G P+ G +G G+P G Sbjct: 557 AKGDRGFDGLPGLPG----DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP----GE 608 Query: 407 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPGVGVA 466 G G +G G PG G PG+ GV G G G + P+ + PG Sbjct: 609 AGPRGL-LGPRGTPGAPGQPGMAGVDGPPGPKG-NMGPQGEPGP----------PGQQGN 656 Query: 467 PGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAAKAQL 526 PG PG G G PG+ PG PG PG + + A Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGA-------- 707 Query: 527 RAAAGLGAGIPGLGVGVGVPG-LGV-GA-GVPGLGVGAGVPGFGAVPGALAAAKAAKYGA 583 G PG +G PG GV GA GV GL G G PG K Sbjct: 708 -------LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG-------FKGDM 753 Query: 584 AVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGV 643 + G G +G +G G G G A + +A + G +G GL G G G Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGY-PGRQGP 812 Query: 644 PGVGGLGGIPPAAAAKAAKYGVAARPG 670 G G G P A K A+ GVA +PG Sbjct: 813 KGSTGFPGFPGANGEKGAR-GVAGKPG 838 Score = 92.0 bits (227), Expect = 2e-18 Identities = 162/522 (31%), Positives = 181/522 (34%), Gaps = 120/522 (22%) Query: 26 PGGVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAV 85 PG G P G PG V PG A G GP G P +P P G G G Sbjct: 1002 PGLKGGEGPQGPPGPVGSPGERGSA---GTAGPIGLPGRPGPQGPPGPAGEKGA------ 1052 Query: 86 TFPGALVPGGVA--DAAAAYKAAKAGAGLGGVPGVGG-LGVSAAPSVPGAVVP--QPGAG 140 PG P G A D AG G PG G G P G+ + G Sbjct: 1053 --PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPP 1110 Query: 141 VKPGKVPGVGLPGVYPGGVLPGARFP----------GVGVLPGVPTGAGVK--PKAPGVG 188 PG VG PG+ G PG R G PG P G++ P PG Sbjct: 1111 GPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170 Query: 189 GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVAGAAGKAG 248 G + +GP G P P P G P A G G P + G + G G G G AG G Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQG-PNGAD---GPQGPPGSVGSVG-GVGEKGEPGEAGNPG 1225 Query: 249 YPTGTGVG--------------PQAAAAAAAKA-----AAKFGAGAAGV----------- 278 P GVG P AA AK K G G Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285 Query: 279 ---LPGVGGA----GVPGVPGAIPGIGGIAGVGTP--------AAAAAAAAAAKAAKYGA 323 GVGG G PG PG PG G AG P AA A K AK A Sbjct: 1286 PAGQDGVGGDKGEDGDPGQPGP-PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344 Query: 324 AAGLVPGGPG-FGP-GVVGVPGA----GVPGV----GVPGA----------GIPVVPGA- 362 A PG G GP G G PG G+PG G+PGA G P +PG Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404 Query: 363 GIPGA-------AVPGVVSP--EAAAKAAAKAAKYGARPGV-GVGGIPTYG--VGAGGFP 410 G PG+ + G++ P E K PG G GGIP +G G P Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464 Query: 411 GF--------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISP 444 G G G G G G+ G PG G PG I P Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQP 1506 Score = 61.2 bits (147), Expect = 3e-09 Identities = 89/310 (28%), Positives = 107/310 (34%), Gaps = 31/310 (10%) Query: 392 PGVGVGGIPTYGVGAG--GFPGFG--VGVGGIPGVAGVPGVGGVPGVGGVPGV------- 440 PG+ V G P AG G PG G G PG G PG G+PG G+PG Sbjct: 397 PGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLML 456 Query: 441 -----GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGV 495 G + +A +A ++ +A + PG G+ PG PG Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIA--LRGPPG---PMGLTGRPGPVGGPGSSG 511 Query: 496 APGVGVAPG-IGPGGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGV 554 A G PG GP GV K + R A G G+PG G G G+ Sbjct: 512 AKGESGDPGPQGPRGVQGPPGPTGKPGKRG--RPGADGGRGMPGEPGAKGDRGFDGLPGL 569 Query: 555 PGLGVGAGVPGFGAVPG-----ALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGP 609 PG G G PG + +PG G G LG G PG G Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629 Query: 610 AAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGGIPPAAAAKAAKYGVAARP 669 A G G G G G G+PG G G PP K G+A P Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQG-NPGPQGLPGPQGPIG-PPGEKGPQGKPGLAGLP 687 Query: 670 GFGLSPIFPG 679 G P PG Sbjct: 688 GADGPPGHPG 697 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.144 0.444 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,982,538 Number of Sequences: 37866 Number of extensions: 3041116 Number of successful extensions: 60336 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 523 Number of HSP's successfully gapped in prelim test: 1039 Number of HSP's that attempted gapping in prelim test: 13835 Number of HSP's gapped (non-prelim): 13600 length of query: 692 length of database: 18,247,518 effective HSP length: 109 effective length of query: 583 effective length of database: 14,120,124 effective search space: 8232032292 effective search space used: 8232032292 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.