Guide to the Human Genome
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Search of human proteins with 40805823

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
         (1626 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]              3474   0.0  
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]    1781   0.0  
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]      1032   0.0  
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   952   0.0  
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   951   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   951   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      920   0.0  
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   916   0.0  
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   902   0.0  
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         901   0.0  
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   894   0.0  
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   893   0.0  
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   893   0.0  
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   893   0.0  
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    892   0.0  
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     890   0.0  
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   883   0.0  
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        881   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   880   0.0  
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   880   0.0  
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   880   0.0  
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   879   0.0  
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   878   0.0  
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     866   0.0  
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      865   0.0  
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   855   0.0  
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]    828   0.0  
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...   820   0.0  
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...   820   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    786   0.0  

>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 3474 bits (9009), Expect = 0.0
 Identities = 1626/1626 (100%), Positives = 1626/1626 (100%)

Query: 1    MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQW 60
            MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQW
Sbjct: 1    MAGLRGNAVAGLLWMLLLWSGGGGCQAQRAGCKSVHYDLVFLLDTSSSVGKEDFEKVRQW 60

Query: 61   VANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDA 120
            VANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDA
Sbjct: 61   VANLVDTFEVGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDA 120

Query: 121  LRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEA 180
            LRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEA
Sbjct: 121  LRYITARSFSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEA 180

Query: 181  LKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGT 240
            LKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGT
Sbjct: 181  LKEELEEIASEPKSAHVFHVSDFNAIDKIRGKLRRRLCENVLCPSVRVEGDRFKHTNGGT 240

Query: 241  KEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFR 300
            KEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFR
Sbjct: 241  KEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTEDVFPQGLPDEYAFVTTFR 300

Query: 301  FRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLF 360
            FRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLF
Sbjct: 301  FRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLF 360

Query: 361  DRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQR 420
            DRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQR
Sbjct: 361  DRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKTVIGKRLYDSVPIDFDLQR 420

Query: 421  IVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA 480
            IVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA
Sbjct: 421  IVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA 480

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540
            GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP
Sbjct: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540

Query: 541  PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600
            PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE
Sbjct: 541  PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600

Query: 601  KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660
            KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG
Sbjct: 601  KGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660

Query: 661  APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720
            APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG
Sbjct: 661  APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720

Query: 721  VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780
            VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG
Sbjct: 721  VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780

Query: 781  KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKG 840
            KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKG
Sbjct: 781  KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKG 840

Query: 841  EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP 900
            EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP
Sbjct: 841  EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP 900

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE
Sbjct: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960

Query: 961  GSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGG 1020
            GSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGG
Sbjct: 961  GSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGG 1020

Query: 1021 QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080
            QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD
Sbjct: 1021 QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080

Query: 1081 GAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 1140
            GAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP
Sbjct: 1081 GAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 1140

Query: 1141 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200
            GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP
Sbjct: 1141 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200

Query: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260
            GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA
Sbjct: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260

Query: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320
            GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ
Sbjct: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320

Query: 1321 GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380
            GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE
Sbjct: 1321 GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380

Query: 1381 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440
            GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV
Sbjct: 1381 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440

Query: 1441 GPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPG 1500
            GPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPG
Sbjct: 1441 GPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPG 1500

Query: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGP 1560
            PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGP
Sbjct: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGP 1560

Query: 1561 PGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARP 1620
            PGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARP
Sbjct: 1561 PGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARP 1620

Query: 1621 GNVKGP 1626
            GNVKGP
Sbjct: 1621 GNVKGP 1626


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 1781 bits (4614), Expect = 0.0
 Identities = 826/866 (95%), Positives = 826/866 (95%), Gaps = 35/866 (4%)

Query: 761  PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820
            PG     GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD
Sbjct: 243  PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 302

Query: 821  QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880
            QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG
Sbjct: 303  QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 362

Query: 881  EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 940
            EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG
Sbjct: 363  EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 422

Query: 941  LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 1000
            LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP
Sbjct: 423  LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 482

Query: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 1060
            LGT                    KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG
Sbjct: 483  LGT--------------------KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 522

Query: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120
            SPGSRGLPGFPGPQGPAGRD               GLSSLLSPGDINLLAKDVCNDCPPG
Sbjct: 523  SPGSRGLPGFPGPQGPAGRD---------------GLSSLLSPGDINLLAKDVCNDCPPG 567

Query: 1121 PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 1180
            PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG
Sbjct: 568  PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 627

Query: 1181 QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240
            QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG
Sbjct: 628  QKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687

Query: 1241 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 1300
            EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG
Sbjct: 688  EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 747

Query: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 1360
            QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG
Sbjct: 748  QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 807

Query: 1361 FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 1420
            FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG
Sbjct: 808  FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 867

Query: 1421 HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL 1480
            HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL
Sbjct: 868  HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL 927

Query: 1481 AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE 1540
            AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE
Sbjct: 928  AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE 987

Query: 1541 RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1600
            RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG
Sbjct: 988  RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1047

Query: 1601 PPGQCDPSQCAYFASLAARPGNVKGP 1626
            PPGQCDPSQCAYFASLAARPGNVKGP
Sbjct: 1048 PPGQCDPSQCAYFASLAARPGNVKGP 1073



 Score =  624 bits (1608), Expect = e-178
 Identities = 366/861 (42%), Positives = 426/861 (49%), Gaps = 130/861 (15%)

Query: 545  GSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGER 604
            G K + GEPGE GE GLPG+ G+RG  G  GL G PG  G  GL G  G  G RGEKG  
Sbjct: 244  GLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG-- 301

Query: 605  GLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV---VQQEGLKGEQGA 661
                      D G++G  G  G+ G +GEKG+ GPAGPPG+PG+         + GEQG 
Sbjct: 302  ----------DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351

Query: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721
             G +G  G PG PG +G  G  G  GP G  G +G++G  G PG  G  G  G  G PG 
Sbjct: 352  KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 411

Query: 722  PGPPGPGGSPGL---------PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPP--GTKGEP 770
             GPPG  G+PGL          GE G  G+ G PGP GP G  G  G PGPP  G  GEP
Sbjct: 412  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 471

Query: 771  GERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP 830
            G RG  GLPG  G +G+ G  G+ G PG +G+ G+ G  G PG  G  GD+G  G  GLP
Sbjct: 472  GLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLP 530

Query: 831  GLKGDRGEKGEAGPAGPPGLPGTTSLFTP-----------------HPRMPGEQGPKGEK 873
            G           GP GP G  G +SL +P                  P +PG  G KG+K
Sbjct: 531  GF---------PGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 581

Query: 874  GDPGLPGEPGLQGRPGELGPQGPTGPP---GAKGQEGAHGAPGAAGNPGAPGHVGAPGPS 930
            G PG PG  G +G+ GE GP G  GPP   G +G +G  GA G  G  G  GH G PG  
Sbjct: 582  GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 641

Query: 931  GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK----GKD 986
            GPPG+ G PG  G  G  G  G +G+ G+EG PGP GP G PG PG  G  G+    G  
Sbjct: 642  GPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP 701

Query: 987  GEPGLRGSPGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIG 1045
            GEPG  G PGLPGP G +   G K    ++ A G +   G  G PG  G PG  GD    
Sbjct: 702  GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD---- 757

Query: 1046 VAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105
              GP GP GP G +G PG  G PG PG  GP+G  G  G+ GE G PG PG         
Sbjct: 758  -TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLG------ 810

Query: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG 1165
                        P GPPG PG  G  G +GVPGKPG  G +G++G+ G  G  GPPG  G
Sbjct: 811  ------------PRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 858

Query: 1166 PQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG--------------- 1210
              G  G  G  G  G  G QG PG  G +GPPG PG PG  G+ G               
Sbjct: 859  QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 918

Query: 1211 -----------------------AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR 1247
                                   + G PG  G PGK+G PG  GP G PG PG+ G EG 
Sbjct: 919  LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 978

Query: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
             G  GP GE G  G+PG PG        G +G  G  G PG  GE G     G  G+PG 
Sbjct: 979  SGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGP 1030

Query: 1308 DGDTGPTGPQGPQGPRGPPGK 1328
             G+TGP G  G  GP GPPG+
Sbjct: 1031 QGETGPAGHPGLPGPPGPPGQ 1051



 Score =  444 bits (1143), Expect = e-124
 Identities = 266/598 (44%), Positives = 306/598 (51%), Gaps = 82/598 (13%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQ-------GEKGEKG 533
            G+ GE G+ G  GLPGP G  G  G  G PG  G +GD GIG  G        G+KG  G
Sbjct: 466  GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 525

Query: 534  SLGLPGPPGRDGSKGMRG-----EPGEL-------------GEPGLPGEVGMRGPQGPPG 575
            S GLPG PG  G  G  G      PG++             G PGLPG  G +G +G PG
Sbjct: 526  SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG 585

Query: 576  LPG------PPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPG---PSG 626
             PG        G  G PGL G  G  G +G +GERG DG  G+ GD G  G PG   P G
Sbjct: 586  KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 645

Query: 627  VAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD 686
              GP G  G  G AGPPG+ GS        G++G PGP+G  G PG PG  G  G +G+ 
Sbjct: 646  NPGPPGADGIAGAAGPPGIQGS-------PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698

Query: 687  GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP 746
            GPPG  G  G+ G  GP G  G  G +G  G  G PGP G  G+ GLPG+ G PGK G  
Sbjct: 699  GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 758

Query: 747  GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGL------AGRPGEK 800
            GPTGP G  GP GPPG  G+ G PGE G  G PG+ G +GE G  GL       G PGE 
Sbjct: 759  GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818

Query: 801  GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 860
            GE G+PG  G PG  GE G +GE+G+ G+ G KG  G KG+ G  G PG  G T L  P 
Sbjct: 819  GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 878

Query: 861  PRMPGEQGPKGEKGDPGLPGEPGLQGR-----------PGELGPQGPTG--------PPG 901
              +PGE GP G  G PG PG PGL+G              ELG Q  T         PP 
Sbjct: 879  -GLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 937

Query: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961
                + + G PG  G PG  G  G  GP G PG  G  GL G  G  G +GE+GA G+ G
Sbjct: 938  Y--MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG 995

Query: 962  SPGPVGPRGD---PGAPGLPGPPGKGKDGEPGL---------RGSPGLPGPLGTKAAC 1007
            +PG VG RG+   PG PG PG PG  KDG PG+          G PGLPGP G    C
Sbjct: 996  APG-VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1052



 Score =  223 bits (567), Expect = 2e-57
 Identities = 155/394 (39%), Positives = 180/394 (45%), Gaps = 97/394 (24%)

Query: 1264 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323
            G  GP   R             APG +  +G  G  G++GLPGK G  G  G QG  G  
Sbjct: 220  GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP------GLPGF---------LGPRGPP 1368
            G  G+ G PG+PG P         G +GE G        GLPG           GP GPP
Sbjct: 280  GEKGEAGLPGAPGFP---------GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPP 330

Query: 1369 G-------------EPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 1415
            G              PGE+G  G++G PG PGEPG +G  G+ G +G  GPPG KGQ G 
Sbjct: 331  GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 390

Query: 1416 PGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 1475
             G PG  G+       G PG  G  GP GPPG  G PGLRG +P  +          G++
Sbjct: 391  HGAPGAAGN------PGAPGHVGAPGPSGPPGSVGAPGLRG-TPGKD----------GER 433

Query: 1476 LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP--MGEPGRPGQGGLEGPSG 1533
             E   A              +G PGP GP G  G PG  GP   G+ G PG  G  G  G
Sbjct: 434  GEKGAA------------GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 481

Query: 1534 PIGPKGERGAKGDPGA------PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET 1587
            P+G KG+RGA G PG+      PG+G+ G  GP G PG  G PG    GLPG PGPQ   
Sbjct: 482  PLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG--SRGLPGFPGPQ--- 536

Query: 1588 GPAGHPGL-----PG-------------PPGPPG 1603
            GPAG  GL     PG             PPGPPG
Sbjct: 537  GPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPG 570



 Score =  179 bits (453), Expect = 3e-44
 Identities = 127/335 (37%), Positives = 150/335 (44%), Gaps = 56/335 (16%)

Query: 1321 GPRGPPGKNGSPGSPGEPG-----------------PSGTP-------GQKGSKGENGSP 1356
            GPR  P +N   G+ G  G                 P GT        G +G   +    
Sbjct: 172  GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231

Query: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 1416
                 L  +  PG     G PG+ G  G PG+PG +GE G+ G+ G  G  G  G PG P
Sbjct: 232  RASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 291

Query: 1417 GIP---------GHKGHTGLMGPQGLPGENGPVGPPGPPGQPG-------FPGLRGE-SP 1459
            G P         G KG  GL G +G  GE G  GP GPPG PG        P + GE  P
Sbjct: 292  GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351

Query: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMP--PAYMKSSQGRPGPPGPPGKDGLPGRA--- 1514
              E     +  E G  L+ R   L  Q P  P   K  +G  G PG  G  G PG     
Sbjct: 352  KGEKGDPGLPGEPG--LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 409

Query: 1515 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQP-----G 1568
            GP G PG  G  GL G  G  G +GE+GA G+ G+PG VG RG+ G PG+PG P     G
Sbjct: 410  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 469

Query: 1569 EPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
            EPG    G PG+PGP G  G  G PG+PG PG  G
Sbjct: 470  EPGLR--GSPGLPGPLGTKGDRGAPGIPGSPGSRG 502



 Score =  173 bits (439), Expect = 1e-42
 Identities = 133/385 (34%), Positives = 153/385 (39%), Gaps = 108/385 (28%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
            P  P +     EP  P P      PG +  G         P GE G MG+ G  GLPG  
Sbjct: 698  PGPPGEPGKAGEPGLPGPEGARGPPGFK--GHTGDSGAPGPRGESGAMGLPGQEGLPGKD 755

Query: 499  GDIGAIGPVGAPGP---------------------------KGEKGDVGI-------GPF 524
            GD G  GP G  GP                           KGE G  G+       GP 
Sbjct: 756  GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 815

Query: 525  GQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPG------------ELGEPGLPGE---VGMR 568
            G+ GEKG  G  G+PG PG  G KG RG+PG            + G+PG+PG     G+ 
Sbjct: 816  GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLM 875

Query: 569  GPQG------PPGLPGPPGRVGAPGLQGE------------------------------- 591
            GPQG      P G PGPPG+ G PGL+GE                               
Sbjct: 876  GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 935

Query: 592  ----RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGE---KGDVGPAGPPG 644
                +  +G  G  G  G DG PG+ G  G+ GRPG  G+ GP G    KG+ G  G PG
Sbjct: 936  PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG 995

Query: 645  VPGSVVQQEGLKGEQGAPGPRGHQGAPGP-----PGARGPIGPEGRDGPPGLQGLRGKKG 699
             PG      GL+GE G PG  G  G PG      PG  GP G  G  G PGL G  G  G
Sbjct: 996  APGV-----GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1050

Query: 700  DMGPPGIPGLLGLQGPPGPPGVPGP 724
               P        L   PG   V GP
Sbjct: 1051 QCDPSQCAYFASLAARPG--NVKGP 1073


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score = 1032 bits (2669), Expect = 0.0
 Identities = 653/1622 (40%), Positives = 797/1622 (49%), Gaps = 300/1622 (18%)

Query: 223  CPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEI--LGKRENGAQSSYVRMGSFPVVQS 280
            CP  + EG + +H++     +TGF+L+   S+ +   + K  N      +R+G+ PV Q 
Sbjct: 28   CPPSQQEGLKLEHSSSLPANVTGFNLIHRLSLMKTSAIKKIRNPKGPLILRLGAAPVTQP 87

Query: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340
            T  VFP+GLP+E+A V T   +K + ++ WY++QV D    PQ+S+ ++ + +++E  A 
Sbjct: 88   TRRVFPRGLPEEFALVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLELRAQ 147

Query: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQG 400
            G   D V  +F    V  LFD  WHK+ LS+  +  S+H+DC+   + P+  R  +   G
Sbjct: 148  GQDGDFVSCIF---PVPQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPMRPVG 204

Query: 401  KTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRP 460
               +G       P+ FDLQ++ IYCD      E CC+I    C        PP     R 
Sbjct: 205  HVFLGLDAEQGKPVSFDLQQVHIYCDPELVLEEGCCEILPAGC--------PPETSKARR 256

Query: 461  PTPGSEQI-------GFLKTINCSC---------------PAGEKGEMGV---------- 488
             T  +E I       G + T  C C                  +K E G           
Sbjct: 257  DTQSNELIEINPQSEGKVYT-RCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADE 315

Query: 489  -----------------------AGPMGLPGPKGDIGAIGPVG--------------APG 511
                                    G  GLPGP G  G  G  G              A G
Sbjct: 316  CPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEG 375

Query: 512  PKGEKGDVG-IGPFG----------QGEKGEKGSLGLPGPPGRDGSKG---MRGEPGELG 557
            PKGEKG+ G +GP G          +GEKG+ G  G+PG PGRDG  G   + G  G+ G
Sbjct: 376  PKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKG 435

Query: 558  EPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE-------RGEKGTRGEKGERGLDGFP 610
            +PG  G  G+ G  GPPGLPGPPG +G PG  G+       +G+KG+ G  G+ G  G P
Sbjct: 436  DPGFVGPEGLAGEPGPPGLPGPPG-IGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKP 494

Query: 611  GKPGDTGQQGRP---------------GPSGVAGPQGEKGDVGPA-GPPGVPGSVVQQEG 654
            GKPG  G++G P               G  G  GP+GE GD  PA G PG+       +G
Sbjct: 495  GKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGI-------QG 547

Query: 655  LKGEQGAP--------------GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700
            +KGE+G P                 G  G  G PG   P G  GR G PGL+G +G  G+
Sbjct: 548  IKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLP-GLPGRAGVPGLKGEKGNFGE 606

Query: 701  MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP------------------GLPGEIGFPGK 742
             GP G P      GPPGP G  G  G  G P                   LPG  G  G+
Sbjct: 607  AGPAGSP------GPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660

Query: 743  PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLP---GKPGLRGEIGEQGLAGRPGE 799
            PGPPG  G PGK G  G  G  G KG+ G  G+ G P   G+PGL GE G QG AG  GE
Sbjct: 661  PGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGE 719

Query: 800  KGE------------AGLPGAPGFPGVRGEKGDQ-----GEKGELGLPGLKGDRGEKGEA 842
            KG+              + G PG PG +GE+G +     G+ G+ GLPG++G  G KG  
Sbjct: 720  KGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQ 779

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902
            G  GPPG               G QGP+GE G PGL   PG+QG PG  GP GPTG  GA
Sbjct: 780  GEPGPPG--------------RGVQGPQGEPGAPGL---PGIQGLPGPRGPPGPTGEKGA 822

Query: 903  KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE--- 959
            +G  G  GA G  G PGA       GP G  G  G  GLRGTPG+ G RGEKG  GE   
Sbjct: 823  QGSPGVKGATGPVGPPGA----SVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSC 878

Query: 960  -----------EGSPG-------PVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGL 997
                        G+PG         GP+G PG PG PGPPG    +G  G  GL G PGL
Sbjct: 879  PSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGL 938

Query: 998  PGPLGT--------KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG------------ 1037
               LG+        K+ CG     +    G    KG++G  GIPG PG            
Sbjct: 939  TAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLE 998

Query: 1038 -----------SRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082
                       S GDPG     G+ GPPG  G  G++G PG RG PG PGP GP G  GA
Sbjct: 999  RPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGA 1058

Query: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP---GK 1139
             G+PG  G  G+ GL+ L   GD             PGPPG PG PG  G  G+P   G+
Sbjct: 1059 VGSPGLPGLQGERGLTGL--TGDKG----------EPGPPGQPGYPGATGPPGLPGIKGE 1106

Query: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199
             G  G+ G+KGE GPPG  G PG  GP G +GERG  G  G+KGDQG  G PGF GPPG 
Sbjct: 1107 RGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP 1166

Query: 1200 PGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 1259
            PG PG  G  G  GP   +GS G  GP G  G  G PG PG +G  G DG  G  G+PG 
Sbjct: 1167 PGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGL 1226

Query: 1260 AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGP 1319
             G+PG  GP G  GPPGFKG TG  G PGP+G+ G  G PG  G PG +G+    G  GP
Sbjct: 1227 RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGE---PGAMGP 1283

Query: 1320 QGPRGPPGKNGSPGSPGEPGPS-----GTPGQKGSKGENGSPGLPGFLGP---RGPPGEP 1371
            QG  GPPG  G PG PG+PGP+     G  G +G+ GE G  GLPG  GP    GPPGEP
Sbjct: 1284 QGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEP 1343

Query: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431
            G  G  GKEG PGK G  G  G +GDPG  G KG  G KG+ G PG PG  G  G +GP 
Sbjct: 1344 GTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPP 1403

Query: 1432 GLPGENGPVGPPGP---PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 1488
            G  GE G  G PGP   PG PG PG  G+  + + ++R I++E+ K  + R+AY  ++M 
Sbjct: 1404 GPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRM- 1462

Query: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG 1548
              +       PG PGPPGKDG PGR G  G PG PGQ G EG  G  G +G  G KG+ G
Sbjct: 1463 -QFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKG 1521

Query: 1549 APGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608
              G+G+ GE G PG PG  G PGY K G  G  G QG  G  G PG  G PG  G C+PS
Sbjct: 1522 DIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPS 1581

Query: 1609 QC 1610
             C
Sbjct: 1582 DC 1583



 Score =  728 bits (1878), Expect = 0.0
 Identities = 501/1287 (38%), Positives = 586/1287 (45%), Gaps = 303/1287 (23%)

Query: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSC---PAGEKGEMGVAGPMGLPGP---------K 498
            P PP         G++ +         C   P GEKGE G  GP GLPG          K
Sbjct: 345  PGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEK 404

Query: 499  GDIGAIGPVGAPG------------PKGEKGDVG-IGPFG-QGEKGEKG-----SLGLPG 539
            GD G  G  G PG            PKG+KGD G +GP G  GE G  G      +GLPG
Sbjct: 405  GDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPG 464

Query: 540  -------PPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPP---------------GLP 577
                   PPG  G KG  G PG+ G  G PG+ G++G +G P               GLP
Sbjct: 465  TPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLP 524

Query: 578  GPPGRVGAPG----LQGERGEKGTRGEKGE-----------------RGLDGFPGKPGDT 616
            G PG  G PG     +G+ G +G +GEKGE                  G  G  G PG  
Sbjct: 525  GKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPG-F 583

Query: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG--SVVQQEGLKGEQGAP------------ 662
            G  G PG +GV G +GEKG+ G AGP G PG    V   G+KG +G P            
Sbjct: 584  GLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQD 643

Query: 663  ---------GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQ 713
                     GP G +G PGPPG   P G +G+ G  GL+G +G  G+ G PG PG  G  
Sbjct: 644  GDVRVVALPGPSGEKGEPGPPGFGLP-GKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRP 702

Query: 714  GPPGPPGVPGPPGPGGS--------PGLPGEI----GFPGKPGPPGPTGPPG--KDGPNG 759
            G  G PGV GP GP G         P L G +    G PG+PGP G  GP G  + G  G
Sbjct: 703  GLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPG 762

Query: 760  PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 819
             PG PG +G PG +G  G PG PG       +G+ G  GE G  GLPG  G PG RG  G
Sbjct: 763  QPGLPGVQGPPGLKGVQGEPGPPG-------RGVQGPQGEPGAPGLPGIQGLPGPRGPPG 815

Query: 820  DQGEKGELGLPGLKGDRGEKGEAGPA--GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPG 877
              GEKG  G PG+KG  G  G  G +  GPPG  G     T     PGE+GP+GEKG+PG
Sbjct: 816  PTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQ-TGLRGTPGEKGPRGEKGEPG 874

Query: 878  --------------LPGEPGL-QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG 922
                          +PG PGL  G   + GPQGP G PG  G  G  G  G  GN G PG
Sbjct: 875  ECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPG 934

Query: 923  HVGAPGPSGPPGSVG-------------APGLRGTPGKDGERGEKGAAGEEGSPGPVG-- 967
                PG +   GS+                G R  PG   E+GEKG  G  G PG     
Sbjct: 935  Q---PGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCA 991

Query: 968  --------PR----------GDPG---APGLPGPPG----KGKDGEPGLRGSPGLPGPLG 1002
                    PR          GDPG   +PGLPGPPG    +G++G PG+RGSPG PGP+G
Sbjct: 992  QCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIG 1051

Query: 1003 TKAACGKVRGSENCALGGQCV-------KGDRGAPGIPGSPGSRGDPGI----GVAGPPG 1051
                 G V       L G+         KG+ G PG PG PG+ G PG+    G  G  G
Sbjct: 1052 PPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTG 1111

Query: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK 1111
             +G  G+ G PGS GLPG PGP GP G  G  GN GE+G  G  G      PG       
Sbjct: 1112 SAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGF--PG------- 1162

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171
                  PPGPPG PG  G  G  G   + G EG  G  G  G PG PGPPGI GP G  G
Sbjct: 1163 ------PPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDG 1216

Query: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPG------------------NPGPPGADGIAGAAG 1213
              G DG+ G +GD G  G PG MGPPG                   PGPPG+ G  GA G
Sbjct: 1217 LDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEG 1276

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPG-----------------EEGKEGRDGKPGPPGE 1256
             PG  G  G+ GPPG  GP G PG PG                 E G  G  G+PGPPG 
Sbjct: 1277 EPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGH 1336

Query: 1257 PGKAGEPGLPGPEGARGPPGFKGH------TGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310
            PG  GEPG  G  G  GPPG +G        GD GA G +G++G  G  G  G PGK G 
Sbjct: 1337 PGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGS 1396

Query: 1311 TGPTGPQGPQGPRG---PPGKNGSPGSPGEPGPSG------------------------- 1342
             GP GP GP G RG    PG +GSPG PG PG  G                         
Sbjct: 1397 MGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMA 1456

Query: 1343 --------------TPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388
                           PG+ G  G++G+PG PG     G PG PG+ G  G++G+PG  G 
Sbjct: 1457 YYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPG---APGSPGLPGQIGREGRQGLPGVRGL 1513

Query: 1389 PGFKGERGDPGI-----KGDKGPPGGKGQPG-----DPGIPGHKGHTGLMGPQGLPGENG 1438
            PG KGE+GD GI      G  GPPG +G PG       G  G +G  G+ GP G  G+ G
Sbjct: 1514 PGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPG 1573

Query: 1439 PVGPPGPPGQPGFPGLRGESPSMETLR 1465
              G   P    G   +  + P M+T++
Sbjct: 1574 KAGHCNPSDCFGAMPMEQQYPPMKTMK 1600



 Score =  714 bits (1842), Expect = 0.0
 Identities = 475/1171 (40%), Positives = 550/1171 (46%), Gaps = 226/1171 (19%)

Query: 579  PPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG----RPGPSG----VAGP 630
            PP   GA          G +G KGERGL G PG  G+ G +G    R  P        GP
Sbjct: 317  PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGP 376

Query: 631  QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690
            +GEKG+ G  GP G+PGS     G KG++G  G  G +G PG PG         RDG PG
Sbjct: 377  KGEKGESGALGPSGLPGST----GEKGQKGEKGDGGIKGVPGKPG---------RDGRPG 423

Query: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
               + G KG  G PG  G  GL G PGPPG+PGPPG          IG PG PG PG   
Sbjct: 424  EICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPG----------IGLPGTPGDPG--- 470

Query: 751  PPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ---------------GLAG 795
                 GP GP G  G+ G PG+ G  G PGKPG++GE G+                GL G
Sbjct: 471  -----GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPG 525

Query: 796  RPGEKGEAGLP----GAPGFPGVRGEKGDQ------------------------------ 821
            +PG KGE G P    G PG  G++GEKG+                               
Sbjct: 526  KPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGL 585

Query: 822  -GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP- 879
             G  G  G+PGLKG++G  GEAGPAG PG PG            G  G KG KG+P  P 
Sbjct: 586  PGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPV----------GPAGIKGAKGEPCEPC 635

Query: 880  --------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931
                    G+  +   PG  G +G  GPPG  G  G  G  G  G  G  G  G PG  G
Sbjct: 636  PALSNLQDGDVRVVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPG 694

Query: 932  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP---------VGPRGDPGAPGLPGPPG 982
             PG+ G PGL G PG  G  G KG  G+  +  P          G  G PG  G  GP G
Sbjct: 695  TPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG 754

Query: 983  KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042
             G+ G+PG  G PG+ GP G K   G+          G+ V+G +G PG PG PG +G P
Sbjct: 755  VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPP------GRGVQGPQGEPGAPGLPGIQGLP 808

Query: 1043 GIGVAGPPGPSGPPGDKGSPGSRGLPGFPGP-----QGPAGRDGAPGN------PGERGP 1091
            G    GPPGP+G  G +GSPG +G  G  GP      GP GRDG  G       PGE+GP
Sbjct: 809  G--PRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGP 866

Query: 1092 PGKPGLSSLLSPGDINLLAK-DVCNDCPPGPPGL----PGLPGFKGDKGVPGKPGREGTE 1146
             G+ G      PG+ +  ++ D+     PG PGL       PG +G  G+PG PG  G  
Sbjct: 867  RGEKG-----EPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVP 921

Query: 1147 GKKGEAGPPGLPGPPGIAGPQGS----------------QGERGADG---EVGQKGDQGH 1187
            G +G  G  GLPG PG+    GS                QG+R   G   E G+KGDQG 
Sbjct: 922  GLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGI 981

Query: 1188 PGVPGFMGPPG---NPGPPGADGIAG--AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEE 1242
            PGVPG         +   P A+   G  + G PG  GSPG  GPPG  G  G  G PG  
Sbjct: 982  PGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMR 1041

Query: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302
            G  G  G  GPPG PG  G PGLPG +G RG  G    TGD G PGP G+ G  G  G  
Sbjct: 1042 GSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL---TGDKGEPGPPGQPGYPGATGPP 1098

Query: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---P 1359
            GLPG  G+ G TG  G +G  GPPG  G PG PG  GP G  G +G+ GE G  G    P
Sbjct: 1099 GLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQP 1158

Query: 1360 GFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIP 1419
            GF GP GPPG PG+ G          PG PG + E+G  GI+G  G PG  G PG PGI 
Sbjct: 1159 GFPGPPGPPGFPGKVG---------SPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQ 1209

Query: 1420 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETR 1479
            G  G  GL G  G PG  G  GP GPPG  G PG +G++                     
Sbjct: 1210 GPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGH------------------- 1250

Query: 1480 LAYLLAQMPPAYMKSSQGRPGPPGP---PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 1536
                   +P    K   G+PGPPG    PG +G PG  GP G PG PG  G  GP G  G
Sbjct: 1251 -----PGLPGP--KGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303

Query: 1537 PKGER--GAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPA 1590
            P G    G KGD GA G     GL G+ GPPG PG PGEPG   DG  G  GP G+ G  
Sbjct: 1304 PAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPG--TDGAAGKEGPPGKQG-- 1359

Query: 1591 GHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621
               G PGP G PG       A     A  PG
Sbjct: 1360 -FYGPPGPKGDPGAAGQKGQAGEKGRAGMPG 1389



 Score =  613 bits (1582), Expect = e-175
 Identities = 415/1054 (39%), Positives = 479/1054 (45%), Gaps = 233/1054 (22%)

Query: 460  PPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA---------- 509
            P  PG   +  LK        GEKG  G AGP G PGP G +G  G  GA          
Sbjct: 586  PGLPGRAGVPGLK--------GEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPA 637

Query: 510  --------------PGPKGEKGDVGIGPFG-QGEKGEKGSLGLPGPPGRDGSKGMRGEPG 554
                          PGP GEKG+ G   FG  G++G+ G  GL G  G  G+ G  G PG
Sbjct: 638  LSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPG 697

Query: 555  ELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE----RGEKGTRGEKGERGLDGF- 609
              G PGL GE G++GP GP G  G  G    P LQG      G  G  G KGE+G +G  
Sbjct: 698  TTGRPGLSGEPGVQGPAGPKGEKGD-GCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVG 756

Query: 610  -PGKPGDTGQQGRPGPSGVAGPQGE-----KGDVGPAGPPGVPGSVVQQEGLKGEQGAPG 663
             PGKPG  G  G  GP G+ G QGE     +G  GP G PG PG +   +GL G +G PG
Sbjct: 757  RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPG-LPGIQGLPGPRGPPG 815

Query: 664  P---RGHQGAPGPPGARGPIGPEG--------RDGPPGLQGLRGKKGDMGP--------- 703
            P   +G QG+PG  GA GP+GP G        RDG  G  GLRG  G+ GP         
Sbjct: 816  PTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGE 875

Query: 704  --------------PGIPGL-LGLQ---GPPGPPGVPGPPGPGGSPGL---PGEIGFPGK 742
                          PG PGL +G     GP GPPG+PGPPGP G PGL   PG  G PG+
Sbjct: 876  CSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQ 935

Query: 743  PG----------------------------PPGPTGPPGKDGPNGPPGPPG--------- 765
            PG                             PG     G+ G  G PG PG         
Sbjct: 936  PGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFL 995

Query: 766  --------------TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811
                          ++G+PG  G  GLPG PGL G+ GE+G  G  G  G  G  G PGF
Sbjct: 996  SLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGF 1055

Query: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            PG  G  G  G +GE GL GL GD   KGE GP G PG PG T      P +PG +G +G
Sbjct: 1056 PGAVGSPGLPGLQGERGLTGLTGD---KGEPGPPGQPGYPGATG----PPGLPGIKGERG 1108

Query: 872  EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931
              G  G  GEPG  G  G  GP GP GP G +G +G  G  G  G  G PG  G PGP G
Sbjct: 1109 YTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168

Query: 932  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGL 991
             PG VG+PG  G   + G  G +G +G  GSPGP GP G  G  GL G  GK  DG+PGL
Sbjct: 1169 FPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGK--DGKPGL 1226

Query: 992  RGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGS---PGSRGDPGI---- 1044
            RG PG  GP G     G    + +  L G   KGD G PG PGS   PG+ G+PG     
Sbjct: 1227 RGDPGPAGPPGLMGPPGFKGKTGHPGLPGP--KGDCGKPGPPGSTGRPGAEGEPGAMGPQ 1284

Query: 1045 GVAGPPGPSGPPGDKGSPGSRGLP--GFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS 1102
            G  GPPG  GPPG  G PG  G+   G  G +G  G  G  G PG+ GPPG PG      
Sbjct: 1285 GRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPG--E 1342

Query: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162
            PG      K+     PPG  G  G PG KGD G  G+ G+ G +G+ G  G PG  G  G
Sbjct: 1343 PGTDGAAGKEG----PPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMG 1398

Query: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP-------------------------- 1196
              GP G  GERG  G  G  G  G PGVPG MG                           
Sbjct: 1399 PVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYY 1458

Query: 1197 -------------PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
                         PG PGPPG DG  G  G PG  G PG+ G  G QG  G+ G+PG +G
Sbjct: 1459 TSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKG 1518

Query: 1244 KEG--------RDGKPGPPGEPG--------------KAGEPGLPGPEGARGPPGFKGHT 1281
            ++G         +G PGPPG  G              + G PG+PGP G  G PG  GH 
Sbjct: 1519 EKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHC 1578

Query: 1282 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 1315
              S   G         +P ++  P      GP G
Sbjct: 1579 NPSDCFG--------AMPMEQQYPPMKTMKGPFG 1604



 Score =  360 bits (923), Expect = 8e-99
 Identities = 252/669 (37%), Positives = 298/669 (44%), Gaps = 157/669 (23%)

Query: 1055 PPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            PP   G+  S       GP+G  G  G PG PG +G  G  G        D   ++ D  
Sbjct: 317  PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARG-------NDCVRISPDAP 369

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
              C  GP G  G  G  G  G+PG  G +G +G+KG+ G  G+PG PG     G  GE  
Sbjct: 370  LQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPG---RDGRPGEIC 426

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
              G  GQKGD G  G  G  G PG PG PG  GI    G PG  G PG  GPPGP+G  G
Sbjct: 427  VIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGI----GLPGTPGDPG--GPPGPKGDKG 480

Query: 1235 LPGIPGEEGKEGRDGKPGPPGEPGK---------------AGEPGLPGPEG-------AR 1272
              GIPG+EG  G+ GKPG  GE G                 G PG PGP+G       AR
Sbjct: 481  SSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR 540

Query: 1273 GPPGFKGHTGDSGAP-----------------GPRGESGAMG-----LPGQEGLPGKDGD 1310
            G PG +G  G+ G P                 G  G+ G+ G     LPG+ G+PG  G+
Sbjct: 541  GDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGE 600

Query: 1311 ------TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS---------KGENGS 1355
                   GP G  GP GP GP G  G+ G P EP P+ +  Q G           GE G 
Sbjct: 601  KGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660

Query: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD---KGPPGGKGQ 1412
            PG PGF G  G  G+ GE+G+ G++G  G PG+PG  G  G PG+ G+   +GP G KG+
Sbjct: 661  PGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGE 719

Query: 1413 PGD-----PGIPGH----KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMET 1463
             GD     P + G      G  G  GP+G  G  G VG PG PGQPG PG++G       
Sbjct: 720  KGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG-VGRPGKPGQPGLPGVQG------- 771

Query: 1464 LRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRP 1523
                                     P  +K  QG PGPPG     G+ G  G  G PG P
Sbjct: 772  -------------------------PPGLKGVQGEPGPPGR----GVQGPQGEPGAPGLP 802

Query: 1524 GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPG--IPGQPGEPGYAKD----GL 1577
            G  GL GP GP GP GE+GA+G PG  G    G +GPPG  + G PG  G        G 
Sbjct: 803  GIQGLPGPRGPPGPTGEKGAQGSPGVKGA--TGPVGPPGASVSGPPGRDGQQGQTGLRGT 860

Query: 1578 PGIPGPQGETGPAGH-----------------PGL-------PGPPGPPGQCDPSQCAYF 1613
            PG  GP+GE G  G                  PGL       PGP GPPG   P      
Sbjct: 861  PGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGV 920

Query: 1614 ASLAARPGN 1622
              L   PGN
Sbjct: 921  PGLQGVPGN 929



 Score =  309 bits (792), Expect = 1e-83
 Identities = 203/524 (38%), Positives = 238/524 (45%), Gaps = 103/524 (19%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLK-TINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508
            EP PP  P  P   G   +  +K     +  AGEKGE G  G  GLPGP G  G  G  G
Sbjct: 1082 EPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERG 1141

Query: 509  APGPKGEKGDVGI-------GPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPG 560
              G  GEKGD G        GP G  G  G+ GS G PGP    GS+G+RG  G  G PG
Sbjct: 1142 PQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPG 1201

Query: 561  LPGEVGMRGP---------------QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERG 605
             PG  G++GP               +G PG  GPPG +G PG +G+ G  G  G KG+ G
Sbjct: 1202 PPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCG 1261

Query: 606  LDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV-VQQEGLKGEQGA--- 661
              G PG  G  G +G PG  G  G  G  G VGP GPPG PG   +   GLKG++GA   
Sbjct: 1262 KPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGE 1321

Query: 662  ---------PGPRGHQGAPGPPGARG---------------PIGPEGRDGPPGLQGLRGK 697
                     PGP GH G PG PG  G               P GP+G  G  G +G  G+
Sbjct: 1322 RGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGE 1381

Query: 698  KGDMGPPGIPGLLGLQGPPGPPGV------PGPPGPGGSPGLPGEIGF------------ 739
            KG  G PG PG  G  GP GPPG       PG PGP GSPGLPG  G             
Sbjct: 1382 KGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKR 1441

Query: 740  ------------------------------PGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769
                                          PG+PGPPG  G PG+ G  G PG PG  G 
Sbjct: 1442 FIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGR 1501

Query: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGV--RGEKGDQGEKGEL 827
             G +G  G+ G PG +GE G+ G+ G  GE G  G PG  G PG    G  G  G++G  
Sbjct: 1502 EGRQGLPGVRGLPGTKGEKGDIGI-GIAGENGLPGPPGPQGPPGYGKMGATGPMGQQGIP 1560

Query: 828  GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            G+PG  G  G+ G+AG   P    G   +   +P M   +GP G
Sbjct: 1561 GIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQYPPMKTMKGPFG 1604



 Score = 65.5 bits (158), Expect = 4e-10
 Identities = 51/151 (33%), Positives = 62/151 (41%), Gaps = 22/151 (14%)

Query: 442  PCQVTVVTEPPPPP----PPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497
            P ++      P PP     P RP  PGS  +            G +G  G+ G  GLPG 
Sbjct: 1465 PMEMAAAPGRPGPPGKDGAPGRPGAPGSPGL--------PGQIGREGRQGLPGVRGLPGT 1516

Query: 498  KGD-----IGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE 552
            KG+     IG  G  G PGP G +G  G G  G    G  G  G+PG PG  G  G  G+
Sbjct: 1517 KGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA--TGPMGQQGIPGIPGPPGPMGQPGK 1574

Query: 553  PGELGEPGLPGEVGMRGPQGPP--GLPGPPG 581
             G        G + M   Q PP   + GP G
Sbjct: 1575 AGHCNPSDCFGAMPME-QQYPPMKTMKGPFG 1604


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  952 bits (2462), Expect = 0.0
 Identities = 581/1322 (43%), Positives = 674/1322 (50%), Gaps = 232/1322 (17%)

Query: 442  PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            P  + + + P P   P  P  PG +              G  G  G+ GP+G PGP G +
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQ--------------GLPGPTGIPGPIGPPGPPGLM 203

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----G 557
            G  GP G PGPKG      +G   QG KGEKG  GL GPPG  G    +  P ++    G
Sbjct: 204  GPPGPPGLPGPKG-----NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 558  EPGLPGEVGMRGPQGPPGLPGPPGRVGA-PGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
            + GLPG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  
Sbjct: 259  DQGLPGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGA 670
            G  G PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G 
Sbjct: 316  GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 671  P---GPPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPG--IPGLLGLQGPPGPPGVPG 723
            P   GPPG  GP G    G  GPPG  G RG+KGD GPPG  IPG  GL G PG PG+PG
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 724  PPGPGGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGP----------PGTKGEPG 771
            PPGP G P +P   EI  PG PGPPG  G  G  G  G  G            G  G PG
Sbjct: 436  PPGPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 772  ERGEDGLPGKP---GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828
            + G  GLPG P   G  G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L 
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD--ILT 552

Query: 829  LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEP 882
             PG+KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG P
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 883  GLQGRPGELGPQGPT--GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAP 939
            GL G PG +GP GP   GPPG  G++G     G AGNPG P   G PGP G PG ++  P
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEKGIQ---GVAGNPGQP---GIPGPKGDPGQTITQP 662

Query: 940  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
            G  G PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDK 1059
            P G     G++              G  G PG PG PG +G+PG  + GPPGP G PG K
Sbjct: 723  PPGAPGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 1060 GSPGSRGLPGFPGPQGPAGR---DGAP---------GNPGERGPPGKPGLSSLLSPGDIN 1107
            G+ G +G  GFPGP GP GR   DG P         G PG  GPPG PG+     PG   
Sbjct: 769  GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPG 1162
            +         P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG
Sbjct: 829  IPG-------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP------G 1216
            + G  G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G P      G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 1217 IQGSPGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             +G PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGL
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 1266 PGPEGAR------------GPPGFKGHTGDSGAPGPR------GESGAMGLPGQEGLPGK 1307
            PGP G +            GPPG KG  GD G PGP+      G SG  G PG  GLPG+
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 1308 DGDTGPTGPQ-----GPQGPRGPPGKNGSPGSP------GEPGPSGTPGQKGSKGENGSP 1356
             GD G  G       G  GP+G PG  G PG+P      G+PG  G PG  G+KG+ G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 1357 GLPGFLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            G PG  GP       GPPG PG  G PG  G  G PG+PG  GE+G PG  G  GP G K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1411 GQPGDPGI-----PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465
            G+PG PG      PG  G +G  G  GLPG  G  G PGP G+PGF G  G         
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG--------- 1232

Query: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK--DGLPGRAGPMGEPGRP 1523
                                          QG PGPPG PG   +G  G  GP G PGRP
Sbjct: 1233 -----------------------------VQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263

Query: 1524 GQGGLEGPSGPI------GPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGY---- 1572
            G  GL GP GP       G KGE+G  G PG PG+ GL+G+ GPPG+ G PG PG     
Sbjct: 1264 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1323

Query: 1573 AKDGLPGIP---------GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623
               GLPG+P         G  G  GP G PGL GPPGPPG   PS  +      A P  +
Sbjct: 1324 GDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGI 1383

Query: 1624 KG 1625
             G
Sbjct: 1384 PG 1385



 Score =  944 bits (2439), Expect = 0.0
 Identities = 596/1352 (44%), Positives = 688/1352 (50%), Gaps = 240/1352 (17%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            PP PP  P   G    G +   +   P G  G  G  G  GLPGP G  G IGP G PG 
Sbjct: 145  PPGPPGIPGMKGEP--GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 513  KGEKGDVGI-GPFG------QGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----GEPGL 561
             G  G  G+ GP G      QG KGEKG  GL GPPG  G    +  P ++    G+ GL
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 562  PGEVGMRGPQGPPGLPGPPGRVGAP-GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620
            PG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  G  G
Sbjct: 263  PGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 621  RPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGAPG-- 672
             PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G PG  
Sbjct: 320  YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ 379

Query: 673  -PPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPGI--PGLLGLQGPPGPPGVPGPPGP 727
             PPG  GP G    G  GPPG  G RG+KGD GPPGI  PG  GL G PG PG+PGPPGP
Sbjct: 380  GPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439

Query: 728  GGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT----------KGEPGERGE 775
             G P +P   EI  PG PGPPG  G  G  G  G  G  G            G PG+ G 
Sbjct: 440  AG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 776  DGLPGKPG---LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
             GLPG PG     G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L  PG+
Sbjct: 499  PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGM 556

Query: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEPGLQG 886
            KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG PGL G
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 887  RPGELGPQGPTG--PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAPGLRG 943
             PG +GP GP G  PPG  G++G  G    AGNPG PG    PGP G PG ++  PG  G
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGV---AGNPGQPG---IPGPKGDPGQTITQPGKPG 666

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 1003
             PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PGP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G++              G  G PG PG PG +G+PG  + GPPGP G PG KG+ G
Sbjct: 727  PGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG 772

Query: 1064 SRGLPGFPGPQGPAGR---DGAPG---------NPGERGPPGKPGLSSLLSPGDINLLAK 1111
             +G  GFPGP GP GR   DG PG          PG  GPPG PG+     PG   +   
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG- 831

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166
                  P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG+ G 
Sbjct: 832  ------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG------IQGS 1220
             G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G PG       +G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1221 PGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 1269
            PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGLPGP 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1270 GARG------------PPGFKGHTGDSGAPGPRG------ESGAMGLPGQEGLPGKDGDT 1311
            G +G            PPG KG  GD G PGP+G       SG  G PG  GLPG+ GD 
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1312 GPTGPQ-----GPQGPRGPPGKNGSPGSPG------EPGPSGTPGQKGSKGENGSPGLPG 1360
            G  G       G  GP+G PG  G PG+PG      +PG  G PG  G+KG+ G PG PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 1361 FLGPRGP---------------------------PGEPGEKGVPGKEGVPG------KPG 1387
              GP GP                           PG PGEKG PG++G+PG      +PG
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 1388 EPGF--KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG------LMGPQGLPGENGP 1439
            +PGF   G  G PG+ G KG  G  G PG+PG+PG KG  G      + GP G PG  GP
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 1440 V--------GPPGPPGQPGFPGLRG-ESPSMETLRRLIQEELGKQLETRLAYLLA----Q 1486
                     GP GPPG+PGF GL G E P        I+ E G   +  L  L      Q
Sbjct: 1246 ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 1487 MPPAY-----------MKSSQGRPGPPGPPGK---DGLPGRAGPMGEPGR---PGQGGLE 1529
             PP             MK   G PG PG PG     G+PG AGP GEPG    PG  GL 
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1365

Query: 1530 GPSGP-IGPKGERGAKGDPGAPGV----------GLRGEMGPPGIPGQPGEPGY------ 1572
            GPSG  I  KG+ G  G PG PG+          GL G  GPPG PG+ G PG+      
Sbjct: 1366 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR 1425

Query: 1573 -AKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
                GLPG PG +G  GP G  GL GPPGPPG
Sbjct: 1426 KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  835 bits (2156), Expect = 0.0
 Identities = 511/1145 (44%), Positives = 590/1145 (51%), Gaps = 161/1145 (14%)

Query: 452  PPPPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMG---VAGPMGLPGPKGD--IGAIG 505
            PP PP    P PG+   IG    I      GEKGE G   + GP GLPGP G   +G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 506  PVGAPGPKGEKGDVGIG----PFGQGEKGEKGSLGLPGPPGRDG----------SKGMRG 551
            P G PG +G+KGD G      P   G  G+ G+ GLPGPPG  G            G  G
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 552  EPGELGEPGLPGEVGMRGPQGP-------------------PGLPGPPGRVGAPGLQGER 592
             PG  G+ GL GE G++G +G                    PGLPGPPG +G PG +GE+
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP----SGVAGPQGEKGDVGPAGPPGVPGS 648
            G+ G  G KG  G+ G PG PG  G +G PG      G+ G +GE G  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 649  VVQQ--EGLKGEQGAPG---------PRGHQGAPGPPGARGPIGPEG--RDGPPGLQGLR 695
              Q    GL G +G PG         P G+ G PG PG  GP+GP G    GP G +G++
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 696  GKKGDMGPPGIPGLLGLQGP----PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP 751
            G  G+ G PGIPG  G  G     PG PG+PG PG  G  GLPG+ G PG+PG PG  G 
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 752  PGKDG-PN-GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG--LPG 807
             G+ G P  G PGPPG KG PG  G  G PG PG  G  G  G  G PG KGE G  LPG
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 808  APGFPGVRGEKGDQGEKGELG---------------LPGLKGDRGEKGEAGPAGPPGLPG 852
             PG PG+ G KG  G KG+ G               LPG KGD G  G+ GP GPPGLPG
Sbjct: 758  PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817

Query: 853  TTSLFTPHPR-------MPGEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPP 900
                  P P         PG  G  GEKGDPG     +PG PG +G PG  G  GP GPP
Sbjct: 818  IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            G+ G  G     GA+G PG  G +G  GP GPPG +G PG  G PG    +G+ G  G+ 
Sbjct: 878  GSPGLPGK---AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL---KGDDGLQGQP 931

Query: 961  GSPGPVGPRGDPGAPGLPGPPG---------KGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011
            G PGP G +G  G PGLPGPPG         KG+ GEPGL G PG+ GP G +   G   
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP- 990

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGL 1067
                    GQ   G  G PG+PG PG +G+PG+    G+ GPPG  G  GD G PG +G+
Sbjct: 991  --------GQ--PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP--------- 1118
             G PGP G  G+ G+PG PG++G  G PG+SS+  PG      +      P         
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100

Query: 1119 --PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176
              PG PGLPG PG KG  G+PG PG  G  G KG +GPPG PG PG  GP G  G  G  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 1177 GEVGQKGDQGHPGVPGFMGPPG--------NPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
            G  G+KG  G  G+PG  G  G        NPGPPG  G++G  G  G+ G PG  G PG
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA--GEPGLPGPEGARGPPGFKGHTGDSGA 1286
            P+G  G  G PG +G       PGPPG PG A  G  G PGP+G  G PGF+G  G  G 
Sbjct: 1221 PKGEPGFHGFPGVQGP------PGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGP 1274

Query: 1287 PGPRGESGAMGL---PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 1343
            PG  G  G  G    PGQ GLPG  G  G  GP G QG  G PG NG  G PG PG  G 
Sbjct: 1275 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1334

Query: 1344 PGQKGSKGENGSPGL---PGFLGPRGPPGEPGE-------KGVPGKEGVPGKPGEPGFKG 1393
            PG KG  G  GS G    PG +GP GPPG PG        KG  G  G+PG+PG  G  G
Sbjct: 1335 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1394

Query: 1394 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453
             +G  G+ G  GPPG  G+ G PG  G  G  G  G  G PG  G  GPPGP G  G PG
Sbjct: 1395 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 1454 LRGES 1458
              G S
Sbjct: 1455 PPGTS 1459



 Score =  779 bits (2012), Expect = 0.0
 Identities = 467/1012 (46%), Positives = 524/1012 (51%), Gaps = 112/1012 (11%)

Query: 443  CQVTVVTEPPPPPP-PQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            C  T ++ PP  P  P  P  PGS  +GF          GEKG+ G  GP GLPG  G  
Sbjct: 484  CIGTGISGPPGQPGLPGLPGPPGS--LGF------PGQKGEKGQAGATGPKGLPGIPG-- 533

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL 561
             A G  G PG KGE GD+   P  +G+KGE GS G PG PG  G+ G  G PG  G  G 
Sbjct: 534  -APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 562  PGEV---GMRGPQGPPGLPGPPGRVGA---PGL--QGERGEKGTRGEKGERGLDGFPGKP 613
            PG +   G RGP G PGLPG PG +G    PG    G  GEKG +G  G  G  G PG  
Sbjct: 593  PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPK 652

Query: 614  GDTGQQ-GRPGPSGVAGPQGEKGDVGPAGPPGVPGS--VVQQEGLKGEQGAPG------- 663
            GD GQ   +PG  G+ G  G  GDVG  G PG+PG   +    G KGE G PG       
Sbjct: 653  GDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP 712

Query: 664  -PRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG--------PPGIPGLLGLQG 714
             P+G  G PGPPGA G  G  G +GPPG  G  G KG+ G        PPG+PG  G  G
Sbjct: 713  GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG 772

Query: 715  PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPG--------PPGT 766
            P G  G PGPPGP      PG  G  G PGP G  GP G+ GP GPPG        PPG 
Sbjct: 773  PKGDRGFPGPPGP------PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP 826

Query: 767  KGEPGERGEDGLPGKPGLRGEIGEQGL--AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 824
             G PG  G+ GL G PG +G+ G  GL   G PGE+G  G+PGAPG  G  G  G  G+ 
Sbjct: 827  PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 825  GELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL--------FTPHPRMPGEQGPKGEKGDP 876
            G  G PG KG+ G  G  GP GP G+PG + +            P +PG  G KG KG+P
Sbjct: 887  GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 877  GLPGEPG-----LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931
            GLPG PG     L G  GE G  G  G PG  G +G  G PG  G PG  G  G PGP G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 932  P---PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDG 987
            P   PG  G PGL G PG  G  G+ G  G +G  GP GP G PG PG PG PG KG  G
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 988  EPGLR--GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI- 1044
            +PG+   G PGLPGP G     G      N  + G    GD G PG+PG+PG++G PG+ 
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGY---PGNPGIKGSV--GDPGLPGLPGTPGAKGQPGLP 1121

Query: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS-- 1102
            G  G PGP GP G  G PG+ GLPG PGP G  G  G PG PGE+G PG+ G+       
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1103 -----PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157
                 PG  N           PGPPGLPGL G KGD G+PG PG  G  G KGE G  G 
Sbjct: 1182 GEPGQPGFGN-----------PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF 1230

Query: 1158 PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP--- 1214
            PG  G  GP GS G    +G  G  G QG PG PGF G PG  GPPG  G  G  G    
Sbjct: 1231 PGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGN 1289

Query: 1215 ---PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 1271
               PG+ G PG +G  GP G  G PG PG  G +G  G PG PG PG  G  G+PG  G 
Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349

Query: 1272 RGPPGFKGHTGDSGAPGPRGES-------GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG 1324
             G PG  G  G  G PGP G+S       G  G+PGQ GL G  G  GP G  GP GP G
Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPG 1409

Query: 1325 PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 1376
             PG+NG PG  G  G  G PG  G  G  G  G PG  G +GPPG PG   V
Sbjct: 1410 DPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  763 bits (1971), Expect = 0.0
 Identities = 491/1182 (41%), Positives = 567/1182 (47%), Gaps = 264/1182 (22%)

Query: 646  PGSVVQQEGLKGEQGA---PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG 702
            PGS     G+KGE+G    PG  GH G PG PG  GP GP            RG+KGD G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP------------RGQKGDDG 81

Query: 703  PPGIPGLLGLQGPPGPPGVPGPPG-PG--GSPGLPGEIGFPGKPGP-------------- 745
             PG         PPGP G+ GPPG PG  G+PGLPG  G  G PGP              
Sbjct: 82   IPG---------PPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 746  -PGPTGPPGKDGPNGPPGPPGTKGEPGE---------RGEDGLPGKPGLRGEIGEQGLAG 795
             PG  G PG  GP GPPG PG KGEPG          +G  G PG PG++G  G  G+ G
Sbjct: 133  FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 796  RPGEKGEAGLPGAPGFPGVRGEKGD--------QGEKGELGLPG---------------- 831
              G  G  GL G PG PG+ G KG+        +GEKGE GL G                
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 832  ---LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEK--------------- 873
                KGD+G  G+ GP GPPG+ G            GEQG  G++               
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 874  ---GDPGLPGEPGLQGRPGELGPQGPTGPP-------------GAKGQEGAHGAPGAAGN 917
               GDPG PGEPG  G  G+ G  GP GPP             G KG  G  G PG  G 
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 918  PGAPGHVGAPGPSGPPGS--VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 975
             G PG  G PG  GPPG+  +G PG  G PG+ G++G++G  G    PGP G  G PGAP
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAP 431

Query: 976  GLPGPPG--------------------------KGKDGEPGLRGS--------------- 994
            GLPGPPG                          KG  GE G++G                
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 995  -------PGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046
                   PGLPGP G+    G K    +  A G + + G  GAPG PG PGS+G+PG  +
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG-DI 550

Query: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN---------PGERGPPGKPGL 1097
               PG  G  G+ GSPG+ GLPG PG  G  G  G PG           GERGPPG PGL
Sbjct: 551  LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 1098 SSLLSPGDINLLAKDVCNDCPPGP------------PGLPGLPGFKGDKG----VPGKPG 1141
              L  PG+I  +        PPGP            PG PG+PG KGD G     PGKPG
Sbjct: 611  PGL--PGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1142 REGTEGKKGEA---GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 1198
              G  G+ G+    G PGLPG PG+ G  GS+GE G  G +G  G  G  G PG  GPPG
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPG 725

Query: 1199 NPGPPGADGIAGAAGPPGIQGSPGKEG--PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256
             PG PG  G+ G  GPPG  G  G+ G   PGP GP GLPG  G  G +G  G PGPPG 
Sbjct: 726  APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP 785

Query: 1257 PGKAGEPGLPGPE---------GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
            PG+ G  GLPGP+         G  GPPG  G  G  G PGP G  G +G PG  G+PG+
Sbjct: 786  PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF---LGP 1364
             GD GP G   P    GPPG+ GSPG PG PGP G PG  G  G+ G+ G PG    +G 
Sbjct: 845  KGDPGPPGLDVP----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG-----DPGIP 1419
             GPPG PG  G+PG+ GVPG  G+ G +G+ G PG  G+KG  G  G PG     DP + 
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 1420 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETR 1479
            G KG  G  G  G+PG +GP G  G PG PG PGL G+ P +                  
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ-PGLPG---------------- 1003

Query: 1480 LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGP-- 1537
                    PP      +G PG PG PG  G PG  G +G+ G PG  G+EGP GP G   
Sbjct: 1004 --------PP----GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 1538 -------KGERGAKGDPGAPGVGLRGEMGP---PGIPGQPGEPG----YAKDGLPGIPGP 1583
                    G++G KGDPG   +GL G  GP   PG+PG PG PG        GLPG+PG 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 1584 QGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
             G  G  G PG PG PGPPG    S       L   PG V G
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153



 Score =  705 bits (1819), Expect = 0.0
 Identities = 421/924 (45%), Positives = 479/924 (51%), Gaps = 138/924 (14%)

Query: 439  PSG-PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG---PMGL 494
            P G P  +T   E  PP  P  P  PG+             P GEKG  GVAG     G+
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 495  PGPKGDIGAI----GPVGAPGPKGEKGDVGI----GPFGQ-------GEKGEKG--SLGL 537
            PGPKGD G      G  G PG  G  GDVG+    G  GQ       G KGE G   +GL
Sbjct: 649  PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL 708

Query: 538  PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVG-----APGLQGER 592
            PGPPG    KG  G PG  G PG PG +G+ GP GPPG PGP G  G      PG  G  
Sbjct: 709  PGPPG---PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG----------- 641
            G KG  G KG+RG  G PG PG TG  G PGP G  GP G+ G +GP G           
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 642  PPGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRG 696
            PPG+PG + Q    G+ GE+G PGP G    PGPPG RG  G  G  GP   PG  GL G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 697  KKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG 756
            K G  G PG  G +G+ GPPGPPG  G PG  G PGL G+ G  G+PG PGPTG  G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 757  PNGPPGPPGTK-----GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811
              G PGPPG       G  GE+GE GLPG PG+ G  G QGL G PG+ G +G PG PG 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            PG +G  G  G+ G +G PGLKG  G+ G  GP G  G PG + +    P  PG  G KG
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV-PGQPGSPGLPGQKG 1063

Query: 872  EKGDPGLP-----------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 920
            +KGDPG+            GEPGL G PG  G +G  G PG  G  G  GA G  G PG 
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 921  PGHVGAPGP---SGPPGSVGAPGLRGT------PGKDGERGEKGAAGEEGSPGPVGPRGD 971
            PG  G PGP   SGPPG+ G PG  G       PG+ G  GEKG  G++G PGP G +G+
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183

Query: 972  PGAPGL--PGPPG-------KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQC 1022
            PG PG   PGPPG       KG  G PG+ G+PGLPGP G                    
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE------------------- 1224

Query: 1023 VKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082
              G  G PG+ G PG  G PG  + GP G  GP G  G PG +GL   PGP+GP G  G 
Sbjct: 1225 -PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGL---PGPEGPPGLPGN 1280

Query: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 1142
             G  GE+G PG+PGL                        PGLPGL G +G  G+ G PGR
Sbjct: 1281 GGIKGEKGNPGQPGL------------------------PGLPGLKGDQGPPGLQGNPGR 1316

Query: 1143 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG-------FMG 1195
             G  G KG+ G PG+PG PG+ GP G  G  G +GE G  G  G PG+PG         G
Sbjct: 1317 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1376

Query: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPG 1255
              G PG PG  G+ G  GP G QG PG  GPPG  G +GLPG    +G  GR G PG PG
Sbjct: 1377 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF---DGAGGRKGDPGLPG 1433

Query: 1256 EPGKAGEPGLPGPEGARGPPGFKG 1279
            +PG  G  G PGP+G +GPPG  G
Sbjct: 1434 QPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  697 bits (1799), Expect = 0.0
 Identities = 441/1035 (42%), Positives = 511/1035 (49%), Gaps = 183/1035 (17%)

Query: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769
            L L G P          PG      G  G  G+ G PG  G PG  G  GP GPPG +  
Sbjct: 17   LSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR-- 74

Query: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829
             G++G+DG+PG PG +G  G  GL G PG  G  G+PG  G PG +G  G  G KGE G 
Sbjct: 75   -GQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF 133

Query: 830  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP------KGEKGDPGLPGEPG 883
            P   G  G  G  GP GPPG+PG          M GE G        G KG+PG PG PG
Sbjct: 134  P---GSPGFPGLQGPPGPPGIPG----------MKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 884  LQGRPGEL---GPQGPTGPPGAKGQEGAHGAPGAAGN--------PGAPGHVGAPGPSGP 932
            +QG PG     GP GP GPPG  G  G  G PG  GN         G  G  G  GP GP
Sbjct: 181  IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 933  PGSV-------------------------GAPGLRGTP----GKDGERGEKGAAGEEGSP 963
            PG +                         G PG+RG P    G+ GE+GE+G  G+ G P
Sbjct: 241  PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 964  GPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLG---TKAACGKVRGSE-N 1015
            G  G  G PG PGLPG PG     G+DGE G +G  G PGP G    +   G   G + N
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 1016 CALGG-QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074
              L G    KG+RG PGI G PG  G PG  V GPPGP G PG++G  G  G PG   P 
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP- 419

Query: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134
            GP G DG PG PG  GPPG  G    + P D      ++C   PPGPPG PG  G +G++
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAG--PHIPPSD------EICEPGPPGPPGSPGDKGLQGEQ 471

Query: 1135 GVPGKPG-------REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            GV G  G         G  G  G+ G PGLPGPPG  G  G +GE+G  G  G KG  G 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 1188 PGVPGFMGPPGNPGPPG----ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
            PG PG  G PG+ G PG      G+ G  G  G  G+PG  G PG  G  GLPG+PG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL---PG 1300
            + G     G  G PG  G PGLPG  G  GPPGF       G PGP GE G  G+   PG
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-------GPPGPVGEKGIQGVAGNPG 644

Query: 1301 QEGLPGKDGDTGPTGPQ-GPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSKGENGSP 1356
            Q G+PG  GD G T  Q G  G  G PG++G    PG PG PG  G PG  GSKGE G P
Sbjct: 645  QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP 704

Query: 1357 --GLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-------------- 1397
              GLPG  GP+   G PG PG  G PG+ G+ G PG PGF G +G+              
Sbjct: 705  GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN---GPVGPP--------GPP 1446
            PG KG  GP G +G PG PG PG  G  GL GP+G  G N   GP+GPP        GPP
Sbjct: 765  PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824

Query: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSS--QGRPGPPGP 1504
            G PG PG  G+ P +  +        G++ +     L    PP    S    G PGP GP
Sbjct: 825  GPPGIPGPIGQ-PGLHGIP-------GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGP---------------------------IGP 1537
            PG  GLPG+AG  G PG  G+ G+ GP GP                            GP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 1538 KGERGAKGDPGAPG---------VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETG 1588
             GE+G+KG+PG PG         +G +GE G PG+PG PG  G    G  G+PG  G+ G
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPG 994

Query: 1589 PAGHPGLPGPPGPPG 1603
             +G PGLPGPPGP G
Sbjct: 995  LSGQPGLPGPPGPKG 1009



 Score =  357 bits (916), Expect = 5e-98
 Identities = 242/616 (39%), Positives = 276/616 (44%), Gaps = 166/616 (26%)

Query: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230
            G +G  GE G  G +GHPG+PGF GP G PGP G  G  G  GPPG +G  G  G PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1231 GPSGLPGIPGEEGKEGRDGKPG---PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA- 1286
            G  GLPG+PG +G  G  G PG     GE G  G PG PG +G  GPPG  G  G+ G+ 
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1287 -----PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341
                 PGP+G  G  G PG +GLPG      PTG  GP GP GPPG  G PG PG PGP 
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPG------PTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 1342 GT-----PGQKGSKGE----------------------------------NGSPGLPGFL 1362
            G       G KG KGE                                   G PG PG  
Sbjct: 216  GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 1363 GPRGPP----------GEPGEKGVPGKE------GVPGKPGEPGFKGE---RGDPGIKGD 1403
            GP GPP          GEPG++G PGK+      G+PG PG+PG+ GE    G+ G KGD
Sbjct: 276  GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 1404 KGPP----------------GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP--GP 1445
             GPP                G KG  G PG+PG KG  G  G QG PG  GP G    GP
Sbjct: 336  TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 1446 PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA-------QMPPAYMKSSQGR 1498
            PG PGFPG RG+          I    G   +     L          +PP+      G 
Sbjct: 396  PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 1499 PGPP-------------------------------GPPGKDGLPGRAGPMGEPGRPGQGG 1527
            PGPP                               GPPG+ GLPG  GP G  G PGQ G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 1528 LEGPSGPIGPKGERGAKGDPGAPGV-----------------GLRGEMGPPGIPGQPGEP 1570
             +G +G  GPKG  G  G PGAPG                  G +GE+G PG PG PG P
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 1571 GY-AKDGLPGIPGP---------QGETGPAGHPGLP------GPPGPPGQCDPSQCAY-- 1612
            G   +DGLPG+PGP         +GE GP G+PGLP      GP GPPG   P       
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 1613 FASLAARPG--NVKGP 1626
               +A  PG   + GP
Sbjct: 636  IQGVAGNPGQPGIPGP 651



 Score =  122 bits (305), Expect = 4e-27
 Identities = 92/227 (40%), Positives = 101/227 (44%), Gaps = 47/227 (20%)

Query: 441  GPCQVTVVTEPPPPPPPQRPP---------TPGSEQIGFLKTINCSCPAGEKGEMGVAGP 491
            GP        P P  PP RP           PG    G +K        GEKG  G  G 
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIK--------GEKGNPGQPGL 1295

Query: 492  MGLPGPKGDIGAIG---PVGAPGPKGEKGDVGI----------GPFG----QGEKGEKGS 534
             GLPG KGD G  G     G PG  G KGD G+          GP G     G +GE G 
Sbjct: 1296 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1355

Query: 535  LGLPGPPGRDGS-------KGMRGEPGELGEPGLPGEVGMRGPQG------PPGLPGPPG 581
            +G PGPPG  G        KG  G PG  G+PGL G  G +GPQG      PPG PG  G
Sbjct: 1356 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1415

Query: 582  RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA 628
              G  G  G +G+ G  G+ G RGLDG PG  G  G  G PG S VA
Sbjct: 1416 LPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1462


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  951 bits (2459), Expect = 0.0
 Identities = 580/1325 (43%), Positives = 674/1325 (50%), Gaps = 235/1325 (17%)

Query: 442  PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            P  + + + P P   P  P  PG +              G  G  G+ GP+G PGP G +
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQ--------------GLPGPTGIPGPIGPPGPPGLM 203

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----G 557
            G  GP G PGPKG      +G   QG KGEKG  GL GPPG  G    +  P ++    G
Sbjct: 204  GPPGPPGLPGPKG-----NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 558  EPGLPGEVGMRGPQGPPGLPGPPGRVGA-PGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
            + GLPG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  
Sbjct: 259  DQGLPGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGA 670
            G  G PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G 
Sbjct: 316  GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 671  P---GPPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPG--IPGLLGLQGPPGPPGVPG 723
            P   GPPG  GP G    G  GPPG  G RG+KGD GPPG  IPG  GL G PG PG+PG
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 724  PPGPGGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGP----------PGTKGEPG 771
            PPGP G P +P   EI  PG PGPPG  G  G  G  G  G            G  G PG
Sbjct: 436  PPGPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 772  ERGEDGLPGKP---GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828
            + G  GLPG P   G  G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L 
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD--ILT 552

Query: 829  LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEP 882
             PG+KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG P
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 883  GLQGRPGELGPQGPT--GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAP 939
            GL G PG +GP GP   GPPG  G++G     G AGNPG P   G PGP G PG ++  P
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEKGIQ---GVAGNPGQP---GIPGPKGDPGQTITQP 662

Query: 940  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
            G  G PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDK 1059
            P G     G++              G  G PG PG PG +G+PG  + GPPGP G PG K
Sbjct: 723  PPGAPGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 1060 GSPGSRGLPGFPGPQGPAGR---DGAP---------GNPGERGPPGKPGLSSLLSPGDIN 1107
            G+ G +G  GFPGP GP GR   DG P         G PG  GPPG PG+     PG   
Sbjct: 769  GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPG 1162
            +         P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG
Sbjct: 829  IPG-------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP------G 1216
            + G  G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G P      G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 1217 IQGSPGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             +G PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGL
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 1266 PGPEGAR------------GPPGFKGHTGDSGAPGPR------GESGAMGLPGQEGLPGK 1307
            PGP G +            GPPG KG  GD G PGP+      G SG  G PG  GLPG+
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 1308 DGDTGPTGPQ-----GPQGPRGPPGKNGSPGSP------GEPGPSGTPGQKGSKGENGSP 1356
             GD G  G       G  GP+G PG  G PG+P      G+PG  G PG  G+KG+ G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 1357 GLPGFLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            G PG  GP       GPPG PG  G PG  G  G PG+PG  GE+G PG  G  GP G K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1411 GQPGDPGI-----PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465
            G+PG PG      PG  G +G  G  GLPG  G  G PGP G+PGF G  G         
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG--------- 1232

Query: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK--DGLPGRAGPMGEPGRP 1523
                                          QG PGPPG PG   +G  G  GP G PGRP
Sbjct: 1233 -----------------------------VQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263

Query: 1524 GQGGLEGPSGPIGP---------KGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGY- 1572
            G  G +G  GP GP         KGE+G  G PG PG+ GL+G+ GPPG+ G PG PG  
Sbjct: 1264 GPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1323

Query: 1573 ---AKDGLPGIP---------GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARP 1620
                  GLPG+P         G  G  GP G PGL GPPGPPG   PS  +      A P
Sbjct: 1324 GMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGP 1383

Query: 1621 GNVKG 1625
              + G
Sbjct: 1384 PGIPG 1388



 Score =  938 bits (2425), Expect = 0.0
 Identities = 585/1332 (43%), Positives = 677/1332 (50%), Gaps = 207/1332 (15%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            PP PP  P   G    G +   +   P G  G  G  G  GLPGP G  G IGP G PG 
Sbjct: 145  PPGPPGIPGMKGEP--GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 513  KGEKGDVGI-GPFG------QGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----GEPGL 561
             G  G  G+ GP G      QG KGEKG  GL GPPG  G    +  P ++    G+ GL
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 562  PGEVGMRGPQGPPGLPGPPGRVGAP-GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620
            PG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  G  G
Sbjct: 263  PGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 621  RPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGAPG-- 672
             PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G PG  
Sbjct: 320  YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ 379

Query: 673  -PPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPGI--PGLLGLQGPPGPPGVPGPPGP 727
             PPG  GP G    G  GPPG  G RG+KGD GPPGI  PG  GL G PG PG+PGPPGP
Sbjct: 380  GPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439

Query: 728  GGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT----------KGEPGERGE 775
             G P +P   EI  PG PGPPG  G  G  G  G  G  G            G PG+ G 
Sbjct: 440  AG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 776  DGLPGKPG---LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
             GLPG PG     G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L  PG+
Sbjct: 499  PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGM 556

Query: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEPGLQG 886
            KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG PGL G
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 887  RPGELGPQGPTG--PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAPGLRG 943
             PG +GP GP G  PPG  G++G  G    AGNPG PG    PGP G PG ++  PG  G
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGV---AGNPGQPG---IPGPKGDPGQTITQPGKPG 666

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 1003
             PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PGP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G++              G  G PG PG PG +G+PG  + GPPGP G PG KG+ G
Sbjct: 727  PGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG 772

Query: 1064 SRGLPGFPGPQGPAGR---DGAPG---------NPGERGPPGKPGLSSLLSPGDINLLAK 1111
             +G  GFPGP GP GR   DG PG          PG  GPPG PG+     PG   +   
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG- 831

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166
                  P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG+ G 
Sbjct: 832  ------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG------IQGS 1220
             G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G PG       +G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1221 PGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 1269
            PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGLPGP 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1270 GARG------------PPGFKGHTGDSGAPGPRG------ESGAMGLPGQEGLPGKDGDT 1311
            G +G            PPG KG  GD G PGP+G       SG  G PG  GLPG+ GD 
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1312 GPTGPQ-----GPQGPRGPPGKNGSPGSPG------EPGPSGTPGQKGSKGENGSPGLPG 1360
            G  G       G  GP+G PG  G PG+PG      +PG  G PG  G+KG+ G PG PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 1361 FLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414
              GP       GPPG PG  G PG  G  G PG+PG  GE+G PG  G  GP G KG+PG
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 1415 DPGI-----PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG-ESPSMETLRRLI 1468
             PG      PG  G +G  G  GLPG  G  G PGP G+PGF G  G + P         
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP----- 1240

Query: 1469 QEELGKQLETRLAYLLAQMPPAYMKSS--QGRPGPPGPPG---KDGLPGRAGPMGEPGRP 1523
                G  LE        Q PP     +  QG PGP GPPG     G+ G  G  G+PG P
Sbjct: 1241 -GSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1299

Query: 1524 GQGGLEGPSGPIGPKGE------RGAKGDPGAPGV----GLRGEMGPPGIPGQPGEPGY- 1572
            G  GL+G  GP G +G        G KGDPG PGV    G++G  G PG  G  GEPG  
Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1359

Query: 1573 AKDGLPGIPGPQGET----------------------GPAGHPGLPGPPGPPGQCDPSQC 1610
               G PG+PGP G++                      GP G  GLPGP GPPG    +  
Sbjct: 1360 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL 1419

Query: 1611 AYFASLAARPGN 1622
              F     R G+
Sbjct: 1420 PGFDGAGGRKGD 1431



 Score =  911 bits (2355), Expect = 0.0
 Identities = 573/1363 (42%), Positives = 656/1363 (48%), Gaps = 288/1363 (21%)

Query: 441  GPCQVTVVTEPPPPP----PPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLP 495
            GP  +     PP PP    PP  P  PG +  +G    +N   P GEKGE G+ GP G P
Sbjct: 186  GPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMG----LNFQGPKGEKGEQGLQGPPGPP 241

Query: 496  GP-------------KGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPG 542
            G              KGD G  G  G PGP G +G  G     +GEKGE+G  G  G PG
Sbjct: 242  GQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301

Query: 543  RDGSKGMRGEPGELGEPGLPGEVGMRGP-------------------------------- 570
            +DG  G  G PG  G+PG PGE G  G                                 
Sbjct: 302  KDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 571  -----------------QGPPGLPGPPGRV-----GAPGLQGERGEKGTRGE-----KGE 603
                             QGPPGLPGPPG       G PG  GERG+KG  G       G 
Sbjct: 362  GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 604  RGLDGFPG----------------------KPGDTGQQGRPGPSGVAGPQGEKGD----- 636
             GLDG PG                      +PG  G  G PG  G+ G QG KGD     
Sbjct: 422  PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTC 481

Query: 637  --------VGPAGPPGVPG--------SVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680
                     GP G PG+PG            Q+G KG+ GA GP+G  G PG PGA G  
Sbjct: 482  FNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 681  GPEGRDGP-PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP-------- 731
            G +G  G      G++G KG++G PG PGL GL G PG  G+PG PGP G P        
Sbjct: 542  GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601

Query: 732  -GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGE 790
             G PG  G PG PG  GP GPPG     GPPGP G KG  G  G  G PG PG +G+ G+
Sbjct: 602  RGPPGNPGLPGLPGNIGPMGPPG----FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQ 657

Query: 791  -------QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE-----LGLPGLKGDRGE 838
                    GL G PG  G+ GLPG PG PG  G  G  G KGE     +GLPG  G +G 
Sbjct: 658  TITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGF 717

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD--PGLPGEPGLQGRPGELGPQ-- 894
             G  GP G PG PG   L  P P  PG  GPKGE G   PG PG PGL G  G LGP+  
Sbjct: 718  PGIPGPPGAPGTPGRIGLEGP-PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGD 776

Query: 895  ----GPTGP---------PGAKGQEGAHGAPGAAGNPGAP--GHVGAPGPSGPPGSVGAP 939
                GP GP         PG KG  G +G PG  G PG P  G  G PGP G PG +G P
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836

Query: 940  GLRGTPGKDGE-----------RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDG 987
            GL G PG+ G+            GE+G+ G  G+PGP+GP G PG PG  G  G  G  G
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKG 896

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047
            E G+ G PG PGPLG     G V G +    G   ++G  G PG  G  GS+G+PG+   
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSG-VPGLK----GDDGLQGQPGLPGPTGEKGSKGEPGL--P 949

Query: 1048 GPPGPSGPP--GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105
            GPPGP  P   G KG  G  GLPG PG  GP G  G PG+PG+ G  G+PGL     P  
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 1106 INLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAG 1165
                     N   PG PGL G PG KG  G  G PG +G EG  G +G PG PG PG+ G
Sbjct: 1010 ---------NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 1166 PQGSQGERGAD--------GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGI 1217
             +G +G+ G          G  G+ G  G+PG PG  G  G+PG PG  G  GA G PG+
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 1218 QGSPGKEGPPGPQGPS------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 1271
             G PG  GPPGP+G S      GLPG PG  G  G  G+PGPPGE GK G+ G+PGP G 
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180

Query: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331
            +G PG  G     G PGP G  G  G  G  GLPG  G+ G  GP+G  G  G PG  G 
Sbjct: 1181 KGEPGQPGF----GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP 1236

Query: 1332 PGSPGEPGPS-----GTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK- 1385
            PG PG PGP+     G PG +G  G  G  G  G  GP GPPG PG  G+ G++G PG+ 
Sbjct: 1237 PGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP 1296

Query: 1386 --PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP 1443
              PG PG KG++G PG++G+ G PG  G  GDPG+PG  G  G+ GP G+PG  GP G P
Sbjct: 1297 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1356

Query: 1444 ---GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPG 1500
               GPPG PG PG  G+S                                 +K   G PG
Sbjct: 1357 GLIGPPGPPGLPGPSGQS-------------------------------IIIKGDAGPPG 1385

Query: 1501 PPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGP 1560
             PG PG  GLPG  GP G P            GP GP G+ G  G PG  G G  G  G 
Sbjct: 1386 IPGQPGLKGLPGPQGPQGLP------------GPTGPPGDPGRNGLPGFDGAG--GRKGD 1431

Query: 1561 PGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
            PG+PGQPG       GL G PGP          GL GPPGPPG
Sbjct: 1432 PGLPGQPG-----TRGLDGPPGPD---------GLQGPPGPPG 1460



 Score =  836 bits (2160), Expect = 0.0
 Identities = 507/1142 (44%), Positives = 587/1142 (51%), Gaps = 152/1142 (13%)

Query: 452  PPPPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMG---VAGPMGLPGPKGD--IGAIG 505
            PP PP    P PG+   IG    I      GEKGE G   + GP GLPGP G   +G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 506  PVGAPGPKGEKGDVGIG----PFGQGEKGEKGSLGLPGPPGRDG----------SKGMRG 551
            P G PG +G+KGD G      P   G  G+ G+ GLPGPPG  G            G  G
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 552  EPGELGEPGLPGEVGMRGPQGP-------------------PGLPGPPGRVGAPGLQGER 592
             PG  G+ GL GE G++G +G                    PGLPGPPG +G PG +GE+
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP----SGVAGPQGEKGDVGPAGPPGVPGS 648
            G+ G  G KG  G+ G PG PG  G +G PG      G+ G +GE G  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 649  VVQQ--EGLKGEQGAPG---------PRGHQGAPGPPGARGPIGPEG--RDGPPGLQGLR 695
              Q    GL G +G PG         P G+ G PG PG  GP+GP G    GP G +G++
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 696  GKKGDMGPPGIPGLLGLQGP----PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP 751
            G  G+ G PGIPG  G  G     PG PG+PG PG  G  GLPG+ G PG+PG PG  G 
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 752  PGKDG-PN-GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG--LPG 807
             G+ G P  G PGPPG KG PG  G  G PG PG  G  G  G  G PG KGE G  LPG
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 808  APGFPGVRGEKGDQGEKGELG---------------LPGLKGDRGEKGEAGPAGPPGLPG 852
             PG PG+ G KG  G KG+ G               LPG KGD G  G+ GP GPPGLPG
Sbjct: 758  PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817

Query: 853  TTSLFTPHPR-------MPGEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPP 900
                  P P         PG  G  GEKGDPG     +PG PG +G PG  G  GP GPP
Sbjct: 818  IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            G+ G  G     GA+G PG  G +G  GP GPPG +G PG  G PG    +G+ G  G+ 
Sbjct: 878  GSPGLPGK---AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL---KGDDGLQGQP 931

Query: 961  GSPGPVGPRGDPGAPGLPGPPG---------KGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011
            G PGP G +G  G PGLPGPPG         KG+ GEPGL G PG+ GP G +   G   
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP- 990

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGL 1067
                    GQ   G  G PG+PG PG +G+PG+    G+ GPPG  G  GD G PG +G+
Sbjct: 991  --------GQ--PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP--------- 1118
             G PGP G  G+ G+PG PG++G  G PG+SS+  PG      +      P         
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100

Query: 1119 --PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176
              PG PGLPG PG KG  G+PG PG  G  G KG +GPPG PG PG  GP G  G  G  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 1177 GEVGQKGDQGHPGVPGFMGPPG--------NPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
            G  G+KG  G  G+PG  G  G        NPGPPG  G++G  G  G+ G PG  G PG
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPP-----GEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283
            P+G  G  G PG +G  G  G PGP      G PG  G PG PGP G +G PG +G  G 
Sbjct: 1221 PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGL 1280

Query: 1284 SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT 1343
             G  G +GE G  G PG  GLPG  GD GP G QG  G  G  G  G PG PG PG  G 
Sbjct: 1281 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1340

Query: 1344 PGQKGSKGENGSPGLPGFLGPRGPPGEPGE-------KGVPGKEGVPGKPGEPGFKGERG 1396
             G  G  G  G  G PG +GP GPPG PG        KG  G  G+PG+PG  G  G +G
Sbjct: 1341 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1400

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456
              G+ G  GPPG  G+ G PG  G  G  G  G  G PG  G  GPPGP G  G PG  G
Sbjct: 1401 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460

Query: 1457 ES 1458
             S
Sbjct: 1461 TS 1462



 Score =  763 bits (1971), Expect = 0.0
 Identities = 491/1182 (41%), Positives = 567/1182 (47%), Gaps = 264/1182 (22%)

Query: 646  PGSVVQQEGLKGEQGA---PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG 702
            PGS     G+KGE+G    PG  GH G PG PG  GP GP            RG+KGD G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP------------RGQKGDDG 81

Query: 703  PPGIPGLLGLQGPPGPPGVPGPPG-PG--GSPGLPGEIGFPGKPGP-------------- 745
             PG         PPGP G+ GPPG PG  G+PGLPG  G  G PGP              
Sbjct: 82   IPG---------PPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 746  -PGPTGPPGKDGPNGPPGPPGTKGEPGE---------RGEDGLPGKPGLRGEIGEQGLAG 795
             PG  G PG  GP GPPG PG KGEPG          +G  G PG PG++G  G  G+ G
Sbjct: 133  FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 796  RPGEKGEAGLPGAPGFPGVRGEKGD--------QGEKGELGLPG---------------- 831
              G  G  GL G PG PG+ G KG+        +GEKGE GL G                
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 832  ---LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEK--------------- 873
                KGD+G  G+ GP GPPG+ G            GEQG  G++               
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 874  ---GDPGLPGEPGLQGRPGELGPQGPTGPP-------------GAKGQEGAHGAPGAAGN 917
               GDPG PGEPG  G  G+ G  GP GPP             G KG  G  G PG  G 
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 918  PGAPGHVGAPGPSGPPGS--VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 975
             G PG  G PG  GPPG+  +G PG  G PG+ G++G++G  G    PGP G  G PGAP
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAP 431

Query: 976  GLPGPPG--------------------------KGKDGEPGLRGS--------------- 994
            GLPGPPG                          KG  GE G++G                
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 995  -------PGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046
                   PGLPGP G+    G K    +  A G + + G  GAPG PG PGS+G+PG  +
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG-DI 550

Query: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN---------PGERGPPGKPGL 1097
               PG  G  G+ GSPG+ GLPG PG  G  G  G PG           GERGPPG PGL
Sbjct: 551  LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 1098 SSLLSPGDINLLAKDVCNDCPPGP------------PGLPGLPGFKGDKG----VPGKPG 1141
              L  PG+I  +        PPGP            PG PG+PG KGD G     PGKPG
Sbjct: 611  PGL--PGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1142 REGTEGKKGEA---GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 1198
              G  G+ G+    G PGLPG PG+ G  GS+GE G  G +G  G  G  G PG  GPPG
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPG 725

Query: 1199 NPGPPGADGIAGAAGPPGIQGSPGKEG--PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256
             PG PG  G+ G  GPPG  G  G+ G   PGP GP GLPG  G  G +G  G PGPPG 
Sbjct: 726  APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP 785

Query: 1257 PGKAGEPGLPGPE---------GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
            PG+ G  GLPGP+         G  GPPG  G  G  G PGP G  G +G PG  G+PG+
Sbjct: 786  PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF---LGP 1364
             GD GP G   P    GPPG+ GSPG PG PGP G PG  G  G+ G+ G PG    +G 
Sbjct: 845  KGDPGPPGLDVP----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG-----DPGIP 1419
             GPPG PG  G+PG+ GVPG  G+ G +G+ G PG  G+KG  G  G PG     DP + 
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 1420 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETR 1479
            G KG  G  G  G+PG +GP G  G PG PG PGL G+ P +                  
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ-PGLPG---------------- 1003

Query: 1480 LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGP-- 1537
                    PP      +G PG PG PG  G PG  G +G+ G PG  G+EGP GP G   
Sbjct: 1004 --------PP----GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 1538 -------KGERGAKGDPGAPGVGLRGEMGP---PGIPGQPGEPG----YAKDGLPGIPGP 1583
                    G++G KGDPG   +GL G  GP   PG+PG PG PG        GLPG+PG 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 1584 QGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
             G  G  G PG PG PGPPG    S       L   PG V G
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153



 Score =  727 bits (1876), Expect = 0.0
 Identities = 440/922 (47%), Positives = 491/922 (53%), Gaps = 115/922 (12%)

Query: 439  PSG-PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG---PMGL 494
            P G P  +T   E  PP  P  P  PG+             P GEKG  GVAG     G+
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 495  PGPKGDIGAI----GPVGAPGPKGEKGDVGI----GPFGQ-------GEKGEKG--SLGL 537
            PGPKGD G      G  G PG  G  GDVG+    G  GQ       G KGE G   +GL
Sbjct: 649  PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL 708

Query: 538  PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVG-----APGLQGER 592
            PGPPG    KG  G PG  G PG PG +G+ GP GPPG PGP G  G      PG  G  
Sbjct: 709  PGPPG---PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG----------- 641
            G KG  G KG+RG  G PG PG TG  G PGP G  GP G+ G +GP G           
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 642  PPGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRG 696
            PPG+PG + Q    G+ GE+G PGP G    PGPPG RG  G  G  GP   PG  GL G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 697  KKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG 756
            K G  G PG  G +G+ GPPGPPG  G PG  G PGL G+ G  G+PG PGPTG  G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 757  PNGPPGPPGTK-----GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811
              G PGPPG       G  GE+GE GLPG PG+ G  G QGL G PG+ G +G PG PG 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            PG +G  G  G+ G +G PGLKG  G+ G  GP G  G PG + +    P  PG  G KG
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV-PGQPGSPGLPGQKG 1063

Query: 872  EKGDPGLP--GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA---PGHVGA 926
            +KGDPG+   G PGL G  GE G  G  G PG KG  G  G PG  G PGA   PG  G 
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 927  PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGK 985
            PG  GPPG  G  G  G PG  GE G  G  G  G PGP G +G PG  G+PGP G KG+
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183

Query: 986  DGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG---SRGDP 1042
             G+PG  G+PG PG  G               L GQ  KGD G PGIPG+PG    +G+P
Sbjct: 1184 PGQPGF-GNPGPPGLPG---------------LSGQ--KGDGGLPGIPGNPGLPGPKGEP 1225

Query: 1043 GI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLS 1098
            G     GV GPPGP G PG    P   G  G PGPQGP GR G  G  G  GP G PGL 
Sbjct: 1226 GFHGFPGVQGPPGPPGSPG----PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGL- 1280

Query: 1099 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG---KPGREGTEGKKGEAGPP 1155
                PG+  +  +       PG PGLPGLPG KGD+G PG    PGR G  G KG+ G P
Sbjct: 1281 ----PGNGGIKGEKG----NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1332

Query: 1156 GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG----IAGA 1211
            G+PG PG+ GP G  G  G +GE            PG +GPPG PG PG  G    I G 
Sbjct: 1333 GVPGFPGMKGPSGVPGSAGPEGE------------PGLIGPPGPPGLPGPSGQSIIIKGD 1380

Query: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 1271
            AGPPGI G PG +G PGPQGP GLPG  G  G  GR+G PG  G  G+ G+PGLPG  G 
Sbjct: 1381 AGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGT 1440

Query: 1272 RGPPGFKGHTGDSGAPGPRGES 1293
            RG  G  G  G  G PGP G S
Sbjct: 1441 RGLDGPPGPDGLQGPPGPPGTS 1462



 Score =  697 bits (1799), Expect = 0.0
 Identities = 441/1035 (42%), Positives = 511/1035 (49%), Gaps = 183/1035 (17%)

Query: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769
            L L G P          PG      G  G  G+ G PG  G PG  G  GP GPPG +  
Sbjct: 17   LSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR-- 74

Query: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829
             G++G+DG+PG PG +G  G  GL G PG  G  G+PG  G PG +G  G  G KGE G 
Sbjct: 75   -GQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF 133

Query: 830  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP------KGEKGDPGLPGEPG 883
            P   G  G  G  GP GPPG+PG          M GE G        G KG+PG PG PG
Sbjct: 134  P---GSPGFPGLQGPPGPPGIPG----------MKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 884  LQGRPGEL---GPQGPTGPPGAKGQEGAHGAPGAAGN--------PGAPGHVGAPGPSGP 932
            +QG PG     GP GP GPPG  G  G  G PG  GN         G  G  G  GP GP
Sbjct: 181  IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 933  PGSV-------------------------GAPGLRGTP----GKDGERGEKGAAGEEGSP 963
            PG +                         G PG+RG P    G+ GE+GE+G  G+ G P
Sbjct: 241  PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 964  GPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLG---TKAACGKVRGSE-N 1015
            G  G  G PG PGLPG PG     G+DGE G +G  G PGP G    +   G   G + N
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 1016 CALGG-QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074
              L G    KG+RG PGI G PG  G PG  V GPPGP G PG++G  G  G PG   P 
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP- 419

Query: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134
            GP G DG PG PG  GPPG  G    + P D      ++C   PPGPPG PG  G +G++
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAG--PHIPPSD------EICEPGPPGPPGSPGDKGLQGEQ 471

Query: 1135 GVPGKPG-------REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            GV G  G         G  G  G+ G PGLPGPPG  G  G +GE+G  G  G KG  G 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 1188 PGVPGFMGPPGNPGPPG----ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
            PG PG  G PG+ G PG      G+ G  G  G  G+PG  G PG  G  GLPG+PG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL---PG 1300
            + G     G  G PG  G PGLPG  G  GPPGF       G PGP GE G  G+   PG
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-------GPPGPVGEKGIQGVAGNPG 644

Query: 1301 QEGLPGKDGDTGPTGPQ-GPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSKGENGSP 1356
            Q G+PG  GD G T  Q G  G  G PG++G    PG PG PG  G PG  GSKGE G P
Sbjct: 645  QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP 704

Query: 1357 --GLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-------------- 1397
              GLPG  GP+   G PG PG  G PG+ G+ G PG PGF G +G+              
Sbjct: 705  GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN---GPVGPP--------GPP 1446
            PG KG  GP G +G PG PG PG  G  GL GP+G  G N   GP+GPP        GPP
Sbjct: 765  PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824

Query: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSS--QGRPGPPGP 1504
            G PG PG  G+ P +  +        G++ +     L    PP    S    G PGP GP
Sbjct: 825  GPPGIPGPIGQ-PGLHGIP-------GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGP---------------------------IGP 1537
            PG  GLPG+AG  G PG  G+ G+ GP GP                            GP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 1538 KGERGAKGDPGAPG---------VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETG 1588
             GE+G+KG+PG PG         +G +GE G PG+PG PG  G    G  G+PG  G+ G
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPG 994

Query: 1589 PAGHPGLPGPPGPPG 1603
             +G PGLPGPPGP G
Sbjct: 995  LSGQPGLPGPPGPKG 1009



 Score =  357 bits (916), Expect = 5e-98
 Identities = 242/616 (39%), Positives = 276/616 (44%), Gaps = 166/616 (26%)

Query: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230
            G +G  GE G  G +GHPG+PGF GP G PGP G  G  G  GPPG +G  G  G PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1231 GPSGLPGIPGEEGKEGRDGKPG---PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA- 1286
            G  GLPG+PG +G  G  G PG     GE G  G PG PG +G  GPPG  G  G+ G+ 
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1287 -----PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341
                 PGP+G  G  G PG +GLPG      PTG  GP GP GPPG  G PG PG PGP 
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPG------PTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 1342 GT-----PGQKGSKGE----------------------------------NGSPGLPGFL 1362
            G       G KG KGE                                   G PG PG  
Sbjct: 216  GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 1363 GPRGPP----------GEPGEKGVPGKE------GVPGKPGEPGFKGE---RGDPGIKGD 1403
            GP GPP          GEPG++G PGK+      G+PG PG+PG+ GE    G+ G KGD
Sbjct: 276  GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 1404 KGPP----------------GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP--GP 1445
             GPP                G KG  G PG+PG KG  G  G QG PG  GP G    GP
Sbjct: 336  TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 1446 PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA-------QMPPAYMKSSQGR 1498
            PG PGFPG RG+          I    G   +     L          +PP+      G 
Sbjct: 396  PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 1499 PGPP-------------------------------GPPGKDGLPGRAGPMGEPGRPGQGG 1527
            PGPP                               GPPG+ GLPG  GP G  G PGQ G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 1528 LEGPSGPIGPKGERGAKGDPGAPGV-----------------GLRGEMGPPGIPGQPGEP 1570
             +G +G  GPKG  G  G PGAPG                  G +GE+G PG PG PG P
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 1571 GY-AKDGLPGIPGP---------QGETGPAGHPGLP------GPPGPPGQCDPSQCAY-- 1612
            G   +DGLPG+PGP         +GE GP G+PGLP      GP GPPG   P       
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 1613 FASLAARPG--NVKGP 1626
               +A  PG   + GP
Sbjct: 636  IQGVAGNPGQPGIPGP 651



 Score =  239 bits (611), Expect = 1e-62
 Identities = 148/326 (45%), Positives = 169/326 (51%), Gaps = 41/326 (12%)

Query: 438  IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGE-----MGVAGPM 492
            +P  P  V     P  P PP     PG + I          PAG+KGE      G  GP 
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI--------PGPAGQKGEPGQPGFGNPGPP 1195

Query: 493  GLPG---PKGD---IGAIGPVGAPGPKGEKGDVGI----------GPFGQGEKGEKGSLG 536
            GLPG    KGD    G  G  G PGPKGE G  G           G  G   +G KG+ G
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255

Query: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596
              GPPGR G  G +G PG  G PGLPG  G++G +G PG PG PG  G  G QG  G +G
Sbjct: 1256 PQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1315

Query: 597  TRGEKGERGLDGFPGKPGDTGQQGRPGPSGV---AGPQGEKGDVGPAGPPGVPGSVVQQE 653
              G  G  G+ G PG PG  G  G  GPSGV   AGP+GE G +GP GPPG+PG   Q  
Sbjct: 1316 NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSI 1375

Query: 654  GLKGEQGAPGPRGH---QGAPGP------PGARGPIGPEGRDGPPGLQGLRGKKGDMGPP 704
             +KG+ G PG  G    +G PGP      PG  GP G  GR+G PG  G  G+KGD G P
Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLP 1435

Query: 705  GIPGLLGLQGPPGPPGVPGPPGPGGS 730
            G PG  GL GPPGP G+ GPPGP G+
Sbjct: 1436 GQPGTRGLDGPPGPDGLQGPPGPPGT 1461



 Score =  122 bits (306), Expect = 3e-27
 Identities = 94/230 (40%), Positives = 103/230 (44%), Gaps = 50/230 (21%)

Query: 441  GPCQVTVVTEPPPPPPPQRP-PT-----------PGSEQIGFLKTINCSCPAGEKGEMGV 488
            GP        P P  PP RP PT           PG    G +K        GEKG  G 
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIK--------GEKGNPGQ 1295

Query: 489  AGPMGLPGPKGDIGAIG---PVGAPGPKGEKGDVGI----------GPFG----QGEKGE 531
             G  GLPG KGD G  G     G PG  G KGD G+          GP G     G +GE
Sbjct: 1296 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1355

Query: 532  KGSLGLPGPPGRDGS-------KGMRGEPGELGEPGLPGEVGMRGPQG------PPGLPG 578
             G +G PGPPG  G        KG  G PG  G+PGL G  G +GPQG      PPG PG
Sbjct: 1356 PGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPG 1415

Query: 579  PPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA 628
              G  G  G  G +G+ G  G+ G RGLDG PG  G  G  G PG S VA
Sbjct: 1416 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1465


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  951 bits (2459), Expect = 0.0
 Identities = 579/1319 (43%), Positives = 673/1319 (51%), Gaps = 229/1319 (17%)

Query: 442  PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            P  + + + P P   P  P  PG +              G  G  G+ GP+G PGP G +
Sbjct: 158  PGSIIMSSLPGPKGNPGYPGPPGIQ--------------GLPGPTGIPGPIGPPGPPGLM 203

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----G 557
            G  GP G PGPKG      +G   QG KGEKG  GL GPPG  G    +  P ++    G
Sbjct: 204  GPPGPPGLPGPKG-----NMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 558  EPGLPGEVGMRGPQGPPGLPGPPGRVGA-PGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
            + GLPG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  
Sbjct: 259  DQGLPGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGA 670
            G  G PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G 
Sbjct: 316  GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 671  P---GPPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPG--IPGLLGLQGPPGPPGVPG 723
            P   GPPG  GP G    G  GPPG  G RG+KGD GPPG  IPG  GL G PG PG+PG
Sbjct: 376  PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 724  PPGPGGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGP----------PGTKGEPG 771
            PPGP G P +P   EI  PG PGPPG  G  G  G  G  G            G  G PG
Sbjct: 436  PPGPAG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPG 494

Query: 772  ERGEDGLPGKP---GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828
            + G  GLPG P   G  G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L 
Sbjct: 495  QPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGD--ILT 552

Query: 829  LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEP 882
             PG+KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG P
Sbjct: 553  FPGMKGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNP 608

Query: 883  GLQGRPGELGPQGPT--GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAP 939
            GL G PG +GP GP   GPPG  G++G     G AGNPG P   G PGP G PG ++  P
Sbjct: 609  GLPGLPGNIGPMGPPGFGPPGPVGEKGIQ---GVAGNPGQP---GIPGPKGDPGQTITQP 662

Query: 940  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
            G  G PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PG
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPG 722

Query: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDK 1059
            P G     G++              G  G PG PG PG +G+PG  + GPPGP G PG K
Sbjct: 723  PPGAPGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFK 768

Query: 1060 GSPGSRGLPGFPGPQGPAGR---DGAP---------GNPGERGPPGKPGLSSLLSPGDIN 1107
            G+ G +G  GFPGP GP GR   DG P         G PG  GPPG PG+     PG   
Sbjct: 769  GALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPG 1162
            +         P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG
Sbjct: 829  IPG-------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881

Query: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP------G 1216
            + G  G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G P      G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 1217 IQGSPGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             +G PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGL
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 1266 PGPEGAR------------GPPGFKGHTGDSGAPGPR------GESGAMGLPGQEGLPGK 1307
            PGP G +            GPPG KG  GD G PGP+      G SG  G PG  GLPG+
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQ 1061

Query: 1308 DGDTGPTGPQ-----GPQGPRGPPGKNGSPGSP------GEPGPSGTPGQKGSKGENGSP 1356
             GD G  G       G  GP+G PG  G PG+P      G+PG  G PG  G+KG+ G P
Sbjct: 1062 KGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP 1121

Query: 1357 GLPGFLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            G PG  GP       GPPG PG  G PG  G  G PG+PG  GE+G PG  G  GP G K
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1411 GQPGDPGI-----PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLR 1465
            G+PG PG      PG  G +G  G  GLPG  G  G PGP G+PGF G  G         
Sbjct: 1182 GEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG--------- 1232

Query: 1466 RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK--DGLPGRAGPMGEPGRP 1523
                                          QG PGPPG PG   +G  G  GP G PGRP
Sbjct: 1233 -----------------------------VQGPPGPPGSPGPALEGPKGNPGPQGPPGRP 1263

Query: 1524 GQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMGPPGIPGQPGEPGY----AKD 1575
            G  G EGP G  G  G +G KG+PG PG+    GL+G+ GPPG+ G PG PG        
Sbjct: 1264 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDP 1323

Query: 1576 GLPGIP---------GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
            GLPG+P         G  G  GP G PGL GPPGPPG   PS  +      A P  + G
Sbjct: 1324 GLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1382



 Score =  941 bits (2432), Expect = 0.0
 Identities = 585/1333 (43%), Positives = 678/1333 (50%), Gaps = 215/1333 (16%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            PP PP  P   G    G +   +   P G  G  G  G  GLPGP G  G IGP G PG 
Sbjct: 145  PPGPPGIPGMKGEP--GSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGL 202

Query: 513  KGEKGDVGI-GPFG------QGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL----GEPGL 561
             G  G  G+ GP G      QG KGEKG  GL GPPG  G    +  P ++    G+ GL
Sbjct: 203  MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGL 262

Query: 562  PGEVGMRGPQGPPGLPGPPGRVGAP-GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620
            PG+   RGP GPPG+ GPPG  G   G +GE+GE G RG+ G+ G +G PG PG  G  G
Sbjct: 263  PGD---RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 621  RPGPSGVAGPQGEKGDVGPAGPPGV------PGSVVQQEGLKGEQGAPGPRGHQGAPG-- 672
             PG  G  G +G+KGD GP GPPG+       G  + ++G  G  G PG +G +G PG  
Sbjct: 320  YPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQ 379

Query: 673  -PPGARGPIGPE--GRDGPPGLQGLRGKKGDMGPPGI--PGLLGLQGPPGPPGVPGPPGP 727
             PPG  GP G    G  GPPG  G RG+KGD GPPGI  PG  GL G PG PG+PGPPGP
Sbjct: 380  GPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGP 439

Query: 728  GGSPGLP--GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT----------KGEPGERGE 775
             G P +P   EI  PG PGPPG  G  G  G  G  G  G            G PG+ G 
Sbjct: 440  AG-PHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGL 498

Query: 776  DGLPGKPG---LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
             GLPG PG     G+ GE+G AG  G KG  G+PGAPG PG  G KG+ G+   L  PG+
Sbjct: 499  PGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI--LTFPGM 556

Query: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE------KGDPGLPGEPGLQG 886
            KGD+GE G  G  G PGLPGT         +PG  GPKGE      KG+ G PG PGL G
Sbjct: 557  KGDKGELGSPGAPGLPGLPGTPG----QDGLPGLPGPKGEPGGITFKGERGPPGNPGLPG 612

Query: 887  RPGELGPQGPTG--PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-SVGAPGLRG 943
             PG +GP GP G  PPG  G++G  G    AGNPG PG    PGP G PG ++  PG  G
Sbjct: 613  LPGNIGPMGPPGFGPPGPVGEKGIQGV---AGNPGQPG---IPGPKGDPGQTITQPGKPG 666

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 1003
             PG  G  G+ G  G+ G PG  G  G PG+ G PG PG G  G PG +G PG+PGP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G++              G  G PG PG PG +G+PG  + GPPGP G PG KG+ G
Sbjct: 727  PGTPGRI--------------GLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG 772

Query: 1064 SRGLPGFPGPQGPAGR---DGAPG---------NPGERGPPGKPGLSSLLSPGDINLLAK 1111
             +G  GFPGP GP GR   DG PG          PG  GPPG PG+     PG   +   
Sbjct: 773  PKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG- 831

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166
                  P G PGL G+PG KGD G     VPG PG  G+ G  G  GP G PG PG+ G 
Sbjct: 832  ------PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG------IQGS 1220
             G+ G  G  GE+G  G  G PG  G  G  G PG  G DG+ G  G PG       +G 
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945

Query: 1221 PGKEGPPGPQGPS-----------GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 1269
            PG  GPPGP  P+           GLPGIPG  G +G  G PG PG+PG +G+PGLPGP 
Sbjct: 946  PGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPP 1005

Query: 1270 GARG------------PPGFKGHTGDSGAPGPRG------ESGAMGLPGQEGLPGKDGDT 1311
            G +G            PPG KG  GD G PGP+G       SG  G PG  GLPG+ GD 
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 1312 GPTGPQ-----GPQGPRGPPGKNGSPGSPG------EPGPSGTPGQKGSKGENGSPGLPG 1360
            G  G       G  GP+G PG  G PG+PG      +PG  G PG  G+KG+ G PG PG
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 1361 FLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG 1414
              GP       GPPG PG  G PG  G  G PG+PG  GE+G PG  G  GP G KG+PG
Sbjct: 1126 TPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185

Query: 1415 DPGI-----PGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG-ESPSMETLRRLI 1468
             PG      PG  G +G  G  GLPG  G  G PGP G+PGF G  G + P         
Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP----- 1240

Query: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528
                G  LE        Q PP       GRPG PGP G  GLPG  G  GE G PGQ GL
Sbjct: 1241 -GSPGPALEGPKGNPGPQGPP-------GRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1292

Query: 1529 EGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPG---------------EPGY 1572
             G  G  G +G  G +G+PG PG+ G++G+ G PG+PG PG               EPG 
Sbjct: 1293 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1352

Query: 1573 -AKDGLPGIPGPQGET----------------------GPAGHPGLPGPPGPPGQCDPSQ 1609
                G PG+PGP G++                      GP G  GLPGP GPPG    + 
Sbjct: 1353 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1412

Query: 1610 CAYFASLAARPGN 1622
               F     R G+
Sbjct: 1413 LPGFDGAGGRKGD 1425



 Score =  923 bits (2386), Expect = 0.0
 Identities = 568/1289 (44%), Positives = 648/1289 (50%), Gaps = 238/1289 (18%)

Query: 451  PPPPPPPQRPP-TPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            PP PP  + PP  PG E+             GEKGE G  G  G PG  G+ G  G  G 
Sbjct: 268  PPGPPGIRGPPGPPGGEK-------------GEKGEQGEPGKRGKPGKDGENGQPGIPGL 314

Query: 510  PGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPG----RDGSKGMRGEPGELGEPGLPGEV 565
            PG  G  G+ G      GEKG+KG  G PGPPG    R G+    GE G +G PGLPGE 
Sbjct: 315  PGDPGYPGEPG----RDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEK 370

Query: 566  GMRG---PQGPPGLPGPPGRV-----GAPGLQGERGEKGTRGEKG-----ERGLDGFPG- 611
            G RG    QGPPGLPGPPG       G PG  GERG+KG  G  G       GLDG PG 
Sbjct: 371  GERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430

Query: 612  ---------------------KPGDTGQQGRPGPSGVAGPQGEKGDVG------------ 638
                                 +PG  G  G PG  G+ G QG KGD G            
Sbjct: 431  PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGIS 490

Query: 639  -PAGPPGVPG--------SVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPP 689
             P G PG+PG            Q+G KG+ GA GP+G  G PG PGA G  G +G  G  
Sbjct: 491  GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 690  -GLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG---------LPGEIGF 739
                G++G KG++G PG PGL GL G PG  G+PG PGP G PG          PG  G 
Sbjct: 551  LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 740  PGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ-------G 792
            PG PG  GP GPPG     GPPGP G KG  G  G  G PG PG +G+ G+        G
Sbjct: 611  PGLPGNIGPMGPPGF----GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 793  LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE-----LGLPGLKGDRGEKGEAGPAGP 847
            L G PG  G+ GLPG PG PG  G  G  G KGE     +GLPG  G +G  G  GP G 
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGA 726

Query: 848  PGLPGTTSLFTPHPRMPGEQGPKGEKGD--PGLPGEPGLQGRPGELGPQG------PTGP 899
            PG PG   L  P P  PG  GPKGE G   PG PG PGL G  G LGP+G      P GP
Sbjct: 727  PGTPGRIGLEGP-PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP 785

Query: 900  PGA---------KGQEGAHGAPGAAGNPGAPGH--VGAPGPSGPPGSVGAPGLRGTPGKD 948
            PG          KG  G +G PG  G PG PG    G PGP G PG +G PGL G PG+ 
Sbjct: 786  PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEK 845

Query: 949  GERG-----------EKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPG 996
            G+ G           E+G+ G  G+PGP+GP G PG PG  G  G  G  GE G+ G PG
Sbjct: 846  GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG 905

Query: 997  LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP 1056
             PGPLG     G V G +    G   ++G  G PG  G  GS+G+PG+   GPPGP  P 
Sbjct: 906  PPGPLGIPGRSG-VPGLK----GDDGLQGQPGLPGPTGEKGSKGEPGL--PGPPGPMDPN 958

Query: 1057 --GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
              G KG  G  GLPG PG  GP G  G PG+PG+ G  G+PGL     P           
Sbjct: 959  LLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG--------- 1009

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
            N   PG PGL G PG KG  G  G PG +G EG  G +G PG PG PG+ G +G +G+ G
Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069

Query: 1175 AD--------GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
                      G  G+ G  G+PG PG  G  G+PG PG  G  GA G PG+ G PG  GP
Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129

Query: 1227 PGPQGPSG------LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280
            PGP+G SG      LPG PG  G  G  G+PGPPGE GK G+ G+PGP G +G PG  G 
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340
                G PGP G  G  G  G  GLPG  G+ G  GP+G  G  G PG  G PG PG PGP
Sbjct: 1190 ----GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245

Query: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE---PGFKGERGD 1397
            +   G KG+ G  G PG PG  GP GPPG PG  G+ G++G PG+PG    PG KG++G 
Sbjct: 1246 A-LEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1304

Query: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP---GPPGQPGFPGL 1454
            PG++G+ G PG  G  GDPG+PG  G  G+ GP G+PG  GP G P   GPPG PG PG 
Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGP 1364

Query: 1455 RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 1514
             G+S                                 +K   G PG PG PG  GLPG  
Sbjct: 1365 SGQS-------------------------------IIIKGDAGPPGIPGQPGLKGLPGPQ 1393

Query: 1515 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1574
            GP G P            GP GP G+ G  G PG  G G  G  G PG+PGQPG      
Sbjct: 1394 GPQGLP------------GPTGPPGDPGRNGLPGFDGAG--GRKGDPGLPGQPG-----T 1434

Query: 1575 DGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
             GL G PGP          GL GPPGPPG
Sbjct: 1435 RGLDGPPGPD---------GLQGPPGPPG 1454



 Score =  836 bits (2160), Expect = 0.0
 Identities = 510/1142 (44%), Positives = 588/1142 (51%), Gaps = 158/1142 (13%)

Query: 452  PPPPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMG---VAGPMGLPGPKGD--IGAIG 505
            PP PP    P PG+   IG    I      GEKGE G   + GP GLPGP G   +G  G
Sbjct: 338  PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 506  PVGAPGPKGEKGDVGIG----PFGQGEKGEKGSLGLPGPPGRDG----------SKGMRG 551
            P G PG +G+KGD G      P   G  G+ G+ GLPGPPG  G            G  G
Sbjct: 398  PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 552  EPGELGEPGLPGEVGMRGPQGP-------------------PGLPGPPGRVGAPGLQGER 592
             PG  G+ GL GE G++G +G                    PGLPGPPG +G PG +GE+
Sbjct: 458  PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP----SGVAGPQGEKGDVGPAGPPGVPGS 648
            G+ G  G KG  G+ G PG PG  G +G PG      G+ G +GE G  G  G PG+PG+
Sbjct: 518  GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 649  VVQQ--EGLKGEQGAPG---------PRGHQGAPGPPGARGPIGPEG--RDGPPGLQGLR 695
              Q    GL G +G PG         P G+ G PG PG  GP+GP G    GP G +G++
Sbjct: 578  PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 696  GKKGDMGPPGIPGLLGLQGP----PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP 751
            G  G+ G PGIPG  G  G     PG PG+PG PG  G  GLPG+ G PG+PG PG  G 
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 752  PGKDG-PN-GPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG--LPG 807
             G+ G P  G PGPPG KG PG  G  G PG PG  G  G  G  G PG KGE G  LPG
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPG 757

Query: 808  APGFPGVRGEKGDQGEKGELG---------------LPGLKGDRGEKGEAGPAGPPGLPG 852
             PG PG+ G KG  G KG+ G               LPG KGD G  G+ GP GPPGLPG
Sbjct: 758  PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817

Query: 853  TTSLFTPHPR-------MPGEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPP 900
                  P P         PG  G  GEKGDPG     +PG PG +G PG  G  GP GPP
Sbjct: 818  IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            G+ G  G     GA+G PG  G +G  GP GPPG +G PG  G PG    +G+ G  G+ 
Sbjct: 878  GSPGLPGK---AGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL---KGDDGLQGQP 931

Query: 961  GSPGPVGPRGDPGAPGLPGPPG---------KGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011
            G PGP G +G  G PGLPGPPG         KG+ GEPGL G PG+ GP G +   G   
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDP- 990

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGL 1067
                    GQ   G  G PG+PG PG +G+PG+    G+ GPPG  G  GD G PG +G+
Sbjct: 991  --------GQ--PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP--------- 1118
             G PGP G  G+ G+PG PG++G  G PG+SS+  PG      +      P         
Sbjct: 1041 EGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSV 1100

Query: 1119 --PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176
              PG PGLPG PG KG  G+PG PG  G  G KG +GPPG PG PG  GP G  G  G  
Sbjct: 1101 GDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQP 1160

Query: 1177 GEVGQKGDQGHPGVPGFMGPPG--------NPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
            G  G+KG  G  G+PG  G  G        NPGPPG  G++G  G  G+ G PG  G PG
Sbjct: 1161 GPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA--GEPGLPGPEGARGPPGFKGHTGDSGA 1286
            P+G  G  G PG +G       PGPPG PG A  G  G PGP+G  G PG  G  G  G 
Sbjct: 1221 PKGEPGFHGFPGVQGP------PGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGL 1274

Query: 1287 PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ 1346
            PG  G  G  G PGQ GLPG  G  G  GP G QG  G PG NG  G PG PG  G PG 
Sbjct: 1275 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1334

Query: 1347 KGSKGENGSPGL---PGFLGPRGPPGEPGE-------KGVPGKEGVPGKPGEPGFKGERG 1396
            KG  G  GS G    PG +GP GPPG PG        KG  G  G+PG+PG  G  G +G
Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456
              G+ G  GPPG  G+ G PG  G  G  G  G  G PG  G  GPPGP G  G PG  G
Sbjct: 1395 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454

Query: 1457 ES 1458
             S
Sbjct: 1455 TS 1456



 Score =  781 bits (2018), Expect = 0.0
 Identities = 466/1008 (46%), Positives = 524/1008 (51%), Gaps = 107/1008 (10%)

Query: 443  CQVTVVTEPPPPPP-PQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            C  T ++ PP  P  P  P  PGS  +GF          GEKG+ G  GP GLPG  G  
Sbjct: 484  CIGTGISGPPGQPGLPGLPGPPGS--LGF------PGQKGEKGQAGATGPKGLPGIPG-- 533

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL 561
             A G  G PG KGE GD+   P  +G+KGE GS G PG PG  G+ G  G PG  G  G 
Sbjct: 534  -APGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGE 592

Query: 562  PGEV---GMRGPQGPPGLPGPPGRVGA---PGL--QGERGEKGTRGEKGERGLDGFPGKP 613
            PG +   G RGP G PGLPG PG +G    PG    G  GEKG +G  G  G  G PG  
Sbjct: 593  PGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPK 652

Query: 614  GDTGQQ-GRPGPSGVAGPQGEKGDVGPAGPPGVPGS--VVQQEGLKGEQGAPG------- 663
            GD GQ   +PG  G+ G  G  GDVG  G PG+PG   +    G KGE G PG       
Sbjct: 653  GDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP 712

Query: 664  -PRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG--------PPGIPGLLGLQG 714
             P+G  G PGPPGA G  G  G +GPPG  G  G KG+ G        PPG+PG  G  G
Sbjct: 713  GPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALG 772

Query: 715  PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPG--------PPGT 766
            P G  G PGPPGP      PG  G  G PGP G  GP G+ GP GPPG        PPG 
Sbjct: 773  PKGDRGFPGPPGP------PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP 826

Query: 767  KGEPGERGEDGLPGKPGLRGEIGEQGL--AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 824
             G PG  G+ GL G PG +G+ G  GL   G PGE+G  G+PGAPG  G  G  G  G+ 
Sbjct: 827  PGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 825  GELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL--------FTPHPRMPGEQGPKGEKGDP 876
            G  G PG KG+ G  G  GP GP G+PG + +            P +PG  G KG KG+P
Sbjct: 887  GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 877  GLPGEPG-----LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931
            GLPG PG     L G  GE G  G  G PG  G +G  G PG  G PG  G  G PGP G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 932  P---PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDG 987
            P   PG  G PGL G PG  G  G+ G  G +G  GP GP G PG PG PG PG KG  G
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 988  EPGLR--GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI- 1044
            +PG+   G PGLPGP G     G      N  + G    GD G PG+PG+PG++G PG+ 
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGY---PGNPGIKGSV--GDPGLPGLPGTPGAKGQPGLP 1121

Query: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS-- 1102
            G  G PGP GP G  G PG+ GLPG PGP G  G  G PG PGE+G PG+ G+       
Sbjct: 1122 GFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK 1181

Query: 1103 -----PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157
                 PG  N           PGPPGLPGL G KGD G+PG PG  G  G KGE G  G 
Sbjct: 1182 GEPGQPGFGN-----------PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF 1230

Query: 1158 PGPPGIAGPQGSQGE--RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 1215
            PG  G  GP GS G    G  G  G +G  G PG+PG  GPPG PG  G  G  G  G P
Sbjct: 1231 PGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQP 1290

Query: 1216 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 1275
            G+ G PG +G  GP G  G PG PG  G +G  G PG PG PG  G  G+PG  G  G P
Sbjct: 1291 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEP 1350

Query: 1276 GFKGHTGDSGAPGPRGES-------GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK 1328
            G  G  G  G PGP G+S       G  G+PGQ GL G  G  GP G  GP GP G PG+
Sbjct: 1351 GLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGR 1410

Query: 1329 NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 1376
            NG PG  G  G  G PG  G  G  G  G PG  G +GPPG PG   V
Sbjct: 1411 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  763 bits (1971), Expect = 0.0
 Identities = 491/1182 (41%), Positives = 567/1182 (47%), Gaps = 264/1182 (22%)

Query: 646  PGSVVQQEGLKGEQGA---PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMG 702
            PGS     G+KGE+G    PG  GH G PG PG  GP GP            RG+KGD G
Sbjct: 34   PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGP------------RGQKGDDG 81

Query: 703  PPGIPGLLGLQGPPGPPGVPGPPG-PG--GSPGLPGEIGFPGKPGP-------------- 745
             PG         PPGP G+ GPPG PG  G+PGLPG  G  G PGP              
Sbjct: 82   IPG---------PPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERG 132

Query: 746  -PGPTGPPGKDGPNGPPGPPGTKGEPGE---------RGEDGLPGKPGLRGEIGEQGLAG 795
             PG  G PG  GP GPPG PG KGEPG          +G  G PG PG++G  G  G+ G
Sbjct: 133  FPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPG 192

Query: 796  RPGEKGEAGLPGAPGFPGVRGEKGD--------QGEKGELGLPG---------------- 831
              G  G  GL G PG PG+ G KG+        +GEKGE GL G                
Sbjct: 193  PIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 832  ---LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEK--------------- 873
                KGD+G  G+ GP GPPG+ G            GEQG  G++               
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 874  ---GDPGLPGEPGLQGRPGELGPQGPTGPP-------------GAKGQEGAHGAPGAAGN 917
               GDPG PGEPG  G  G+ G  GP GPP             G KG  G  G PG  G 
Sbjct: 313  GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGE 372

Query: 918  PGAPGHVGAPGPSGPPGS--VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 975
             G PG  G PG  GPPG+  +G PG  G PG+ G++G++G  G    PGP G  G PGAP
Sbjct: 373  RGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPG-ISIPGPPGLDGQPGAP 431

Query: 976  GLPGPPG--------------------------KGKDGEPGLRGS--------------- 994
            GLPGPPG                          KG  GE G++G                
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 995  -------PGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046
                   PGLPGP G+    G K    +  A G + + G  GAPG PG PGS+G+PG  +
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPG-DI 550

Query: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN---------PGERGPPGKPGL 1097
               PG  G  G+ GSPG+ GLPG PG  G  G  G PG           GERGPPG PGL
Sbjct: 551  LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 1098 SSLLSPGDINLLAKDVCNDCPPGP------------PGLPGLPGFKGDKG----VPGKPG 1141
              L  PG+I  +        PPGP            PG PG+PG KGD G     PGKPG
Sbjct: 611  PGL--PGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPG 666

Query: 1142 REGTEGKKGEA---GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 1198
              G  G+ G+    G PGLPG PG+ G  GS+GE G  G +G  G  G  G PG  GPPG
Sbjct: 667  LPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPG 725

Query: 1199 NPGPPGADGIAGAAGPPGIQGSPGKEG--PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGE 1256
             PG PG  G+ G  GPPG  G  G+ G   PGP GP GLPG  G  G +G  G PGPPG 
Sbjct: 726  APGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGP 785

Query: 1257 PGKAGEPGLPGPE---------GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
            PG+ G  GLPGP+         G  GPPG  G  G  G PGP G  G +G PG  G+PG+
Sbjct: 786  PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG-IGVQGPPGPPGIPGPIGQPGLHGIPGE 844

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF---LGP 1364
             GD GP G   P    GPPG+ GSPG PG PGP G PG  G  G+ G+ G PG    +G 
Sbjct: 845  KGDPGPPGLDVP----GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG-----DPGIP 1419
             GPPG PG  G+PG+ GVPG  G+ G +G+ G PG  G+KG  G  G PG     DP + 
Sbjct: 901  MGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960

Query: 1420 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETR 1479
            G KG  G  G  G+PG +GP G  G PG PG PGL G+ P +                  
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQ-PGLPG---------------- 1003

Query: 1480 LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGP-- 1537
                    PP      +G PG PG PG  G PG  G +G+ G PG  G+EGP GP G   
Sbjct: 1004 --------PP----GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 1538 -------KGERGAKGDPGAPGVGLRGEMGP---PGIPGQPGEPG----YAKDGLPGIPGP 1583
                    G++G KGDPG   +GL G  GP   PG+PG PG PG        GLPG+PG 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 1584 QGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
             G  G  G PG PG PGPPG    S       L   PG V G
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153



 Score =  702 bits (1811), Expect = 0.0
 Identities = 421/927 (45%), Positives = 478/927 (51%), Gaps = 147/927 (15%)

Query: 439  PSG-PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAG---PMGL 494
            P G P  +T   E  PP  P  P  PG+             P GEKG  GVAG     G+
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 495  PGPKGDIGAI----GPVGAPGPKGEKGDVGI----GPFGQ-------GEKGEKG--SLGL 537
            PGPKGD G      G  G PG  G  GDVG+    G  GQ       G KGE G   +GL
Sbjct: 649  PGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGL 708

Query: 538  PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVG-----APGLQGER 592
            PGPPG    KG  G PG  G PG PG +G+ GP GPPG PGP G  G      PG  G  
Sbjct: 709  PGPPG---PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 593  GEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG----------- 641
            G KG  G KG+RG  G PG PG TG  G PGP G  GP G+ G +GP G           
Sbjct: 766  GFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 642  PPGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRG 696
            PPG+PG + Q    G+ GE+G PGP G    PGPPG RG  G  G  GP   PG  GL G
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLD-VPGPPGERGSPGIPGAPGPIGPPGSPGLPG 884

Query: 697  KKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDG 756
            K G  G PG  G +G+ GPPGPPG  G PG  G PGL G+ G  G+PG PGPTG  G  G
Sbjct: 885  KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 757  PNGPPGPPGTK-----GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811
              G PGPPG       G  GE+GE GLPG PG+ G  G QGL G PG+ G +G PG PG 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            PG +G  G  G+ G +G PGLKG  G+ G  GP G  G PG + +    P  PG  G KG
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV-PGQPGSPGLPGQKG 1063

Query: 872  EKGDPGLP-----------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 920
            +KGDPG+            GEPGL G PG  G +G  G PG  G  G  GA G  G PG 
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 921  PGHVGAPGP---SGPPGSVGAPGLRGT------PGKDGERGEKGAAGEEGSPGPVGPRGD 971
            PG  G PGP   SGPPG+ G PG  G       PG+ G  GEKG  G++G PGP G +G+
Sbjct: 1124 PGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGE 1183

Query: 972  PGAPGL--PGPPG-------KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQC 1022
            PG PG   PGPPG       KG  G PG+ G+PGLPGP G                    
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE------------------- 1224

Query: 1023 VKGDRGAPGIPGSPGSRGDPGIGVAGP---PGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079
              G  G PG+ G PG  G PG  + GP   PGP GPP         G PG PGP+GP G 
Sbjct: 1225 -PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPP---------GRPGLPGPEGPPGL 1274

Query: 1080 DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK 1139
             G  G  GE+G PG+PGL                        PGLPGL G +G  G+ G 
Sbjct: 1275 PGNGGIKGEKGNPGQPGL------------------------PGLPGLKGDQGPPGLQGN 1310

Query: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG------- 1192
            PGR G  G KG+ G PG+PG PG+ GP G  G  G +GE G  G  G PG+PG       
Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1370

Query: 1193 FMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPG 1252
              G  G PG PG  G+ G  GP G QG PG  GPPG  G +GLPG    +G  GR G PG
Sbjct: 1371 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF---DGAGGRKGDPG 1427

Query: 1253 PPGEPGKAGEPGLPGPEGARGPPGFKG 1279
             PG+PG  G  G PGP+G +GPPG  G
Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  697 bits (1799), Expect = 0.0
 Identities = 441/1035 (42%), Positives = 511/1035 (49%), Gaps = 183/1035 (17%)

Query: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769
            L L G P          PG      G  G  G+ G PG  G PG  G  GP GPPG +  
Sbjct: 17   LSLWGQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPR-- 74

Query: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829
             G++G+DG+PG PG +G  G  GL G PG  G  G+PG  G PG +G  G  G KGE G 
Sbjct: 75   -GQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGF 133

Query: 830  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP------KGEKGDPGLPGEPG 883
            P   G  G  G  GP GPPG+PG          M GE G        G KG+PG PG PG
Sbjct: 134  P---GSPGFPGLQGPPGPPGIPG----------MKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 884  LQGRPGEL---GPQGPTGPPGAKGQEGAHGAPGAAGN--------PGAPGHVGAPGPSGP 932
            +QG PG     GP GP GPPG  G  G  G PG  GN         G  G  G  GP GP
Sbjct: 181  IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 933  PGSV-------------------------GAPGLRGTP----GKDGERGEKGAAGEEGSP 963
            PG +                         G PG+RG P    G+ GE+GE+G  G+ G P
Sbjct: 241  PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 964  GPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLG---TKAACGKVRGSE-N 1015
            G  G  G PG PGLPG PG     G+DGE G +G  G PGP G    +   G   G + N
Sbjct: 301  GKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGN 360

Query: 1016 CALGG-QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074
              L G    KG+RG PGI G PG  G PG  V GPPGP G PG++G  G  G PG   P 
Sbjct: 361  IGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP- 419

Query: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134
            GP G DG PG PG  GPPG  G    + P D      ++C   PPGPPG PG  G +G++
Sbjct: 420  GPPGLDGQPGAPGLPGPPGPAG--PHIPPSD------EICEPGPPGPPGSPGDKGLQGEQ 471

Query: 1135 GVPGKPG-------REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            GV G  G         G  G  G+ G PGLPGPPG  G  G +GE+G  G  G KG  G 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 1188 PGVPGFMGPPGNPGPPG----ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
            PG PG  G PG+ G PG      G+ G  G  G  G+PG  G PG  G  GLPG+PG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL---PG 1300
            + G     G  G PG  G PGLPG  G  GPPGF       G PGP GE G  G+   PG
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-------GPPGPVGEKGIQGVAGNPG 644

Query: 1301 QEGLPGKDGDTGPTGPQ-GPQGPRGPPGKNGS---PGSPGEPGPSGTPGQKGSKGENGSP 1356
            Q G+PG  GD G T  Q G  G  G PG++G    PG PG PG  G PG  GSKGE G P
Sbjct: 645  QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIP 704

Query: 1357 --GLPGFLGPR---GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-------------- 1397
              GLPG  GP+   G PG PG  G PG+ G+ G PG PGF G +G+              
Sbjct: 705  GIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN---GPVGPP--------GPP 1446
            PG KG  GP G +G PG PG PG  G  GL GP+G  G N   GP+GPP        GPP
Sbjct: 765  PGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPP 824

Query: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSS--QGRPGPPGP 1504
            G PG PG  G+ P +  +        G++ +     L    PP    S    G PGP GP
Sbjct: 825  GPPGIPGPIGQ-PGLHGIP-------GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876

Query: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGP---------------------------IGP 1537
            PG  GLPG+AG  G PG  G+ G+ GP GP                            GP
Sbjct: 877  PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936

Query: 1538 KGERGAKGDPGAPG---------VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETG 1588
             GE+G+KG+PG PG         +G +GE G PG+PG PG  G    G  G+PG  G+ G
Sbjct: 937  TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSG--PKGYQGLPGDPGQPG 994

Query: 1589 PAGHPGLPGPPGPPG 1603
             +G PGLPGPPGP G
Sbjct: 995  LSGQPGLPGPPGPKG 1009



 Score =  357 bits (916), Expect = 5e-98
 Identities = 242/616 (39%), Positives = 276/616 (44%), Gaps = 166/616 (26%)

Query: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ 1230
            G +G  GE G  G +GHPG+PGF GP G PGP G  G  G  GPPG +G  G  G PG  
Sbjct: 42   GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 1231 GPSGLPGIPGEEGKEGRDGKPG---PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA- 1286
            G  GLPG+PG +G  G  G PG     GE G  G PG PG +G  GPPG  G  G+ G+ 
Sbjct: 102  GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 1287 -----PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341
                 PGP+G  G  G PG +GLPG      PTG  GP GP GPPG  G PG PG PGP 
Sbjct: 162  IMSSLPGPKGNPGYPGPPGIQGLPG------PTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 1342 GT-----PGQKGSKGE----------------------------------NGSPGLPGFL 1362
            G       G KG KGE                                   G PG PG  
Sbjct: 216  GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 1363 GPRGPP----------GEPGEKGVPGKE------GVPGKPGEPGFKGE---RGDPGIKGD 1403
            GP GPP          GEPG++G PGK+      G+PG PG+PG+ GE    G+ G KGD
Sbjct: 276  GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 1404 KGPP----------------GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP--GP 1445
             GPP                G KG  G PG+PG KG  G  G QG PG  GP G    GP
Sbjct: 336  TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 1446 PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA-------QMPPAYMKSSQGR 1498
            PG PGFPG RG+          I    G   +     L          +PP+      G 
Sbjct: 396  PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 1499 PGPP-------------------------------GPPGKDGLPGRAGPMGEPGRPGQGG 1527
            PGPP                               GPPG+ GLPG  GP G  G PGQ G
Sbjct: 456  PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 1528 LEGPSGPIGPKGERGAKGDPGAPGV-----------------GLRGEMGPPGIPGQPGEP 1570
             +G +G  GPKG  G  G PGAPG                  G +GE+G PG PG PG P
Sbjct: 516  EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 1571 GY-AKDGLPGIPGP---------QGETGPAGHPGLP------GPPGPPGQCDPSQCAY-- 1612
            G   +DGLPG+PGP         +GE GP G+PGLP      GP GPPG   P       
Sbjct: 576  GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 1613 FASLAARPG--NVKGP 1626
               +A  PG   + GP
Sbjct: 636  IQGVAGNPGQPGIPGP 651



 Score =  235 bits (599), Expect = 3e-61
 Identities = 147/323 (45%), Positives = 164/323 (50%), Gaps = 41/323 (12%)

Query: 438  IPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGE-----MGVAGPM 492
            +P  P  V     P  P PP     PG + I          PAG+KGE      G  GP 
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI--------PGPAGQKGEPGQPGFGNPGPP 1195

Query: 493  GLPG---PKGD---IGAIGPVGAPGPKGEKGDVGI----------GPFGQGEKGEKGSLG 536
            GLPG    KGD    G  G  G PGPKGE G  G           G  G   +G KG+ G
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255

Query: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596
              GPPGR G  G  G PG  G  G+ GE G  G  G PGLPG  G  G PGLQG  G  G
Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1315

Query: 597  TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLK 656
              G KG+ GL G PG PG  G  G PG    AGP+GE G +GP GPPG+PG   Q   +K
Sbjct: 1316 LNGMKGDPGLPGVPGFPGMKGPSGVPGS---AGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1372

Query: 657  GEQGAPGPRGH---QGAPGP------PGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIP 707
            G+ G PG  G    +G PGP      PG  GP G  GR+G PG  G  G+KGD G PG P
Sbjct: 1373 GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1432

Query: 708  GLLGLQGPPGPPGVPGPPGPGGS 730
            G  GL GPPGP G+ GPPGP G+
Sbjct: 1433 GTRGLDGPPGPDGLQGPPGPPGT 1455



 Score =  126 bits (316), Expect = 2e-28
 Identities = 92/218 (42%), Positives = 100/218 (45%), Gaps = 32/218 (14%)

Query: 441  GPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500
            GP        P P  PP RP  PG E    L         GEKG  G  G  GLPG KGD
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLP--GNGGIKGEKGNPGQPGLPGLPGLKGD 1301

Query: 501  IGAIG---PVGAPGPKGEKGDVGI----------GPFG----QGEKGEKGSLGLPGPPGR 543
             G  G     G PG  G KGD G+          GP G     G +GE G +G PGPPG 
Sbjct: 1302 QGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361

Query: 544  DGS-------KGMRGEPGELGEPGLPGEVGMRGPQG------PPGLPGPPGRVGAPGLQG 590
             G        KG  G PG  G+PGL G  G +GPQG      PPG PG  G  G  G  G
Sbjct: 1362 PGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGG 1421

Query: 591  ERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA 628
             +G+ G  G+ G RGLDG PG  G  G  G PG S VA
Sbjct: 1422 RKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVA 1459


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  920 bits (2378), Expect = 0.0
 Identities = 532/1192 (44%), Positives = 624/1192 (52%), Gaps = 158/1192 (13%)

Query: 483  KGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG---------------PF--- 524
            +G  G  GP GLPGP G +G  G VG PG +G  G  G+                PF   
Sbjct: 468  EGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527

Query: 525  GQGEKGEKGS-----------------LGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567
            G G+ G KG                  L L GP G  G  G  G  G  G  GL GE G 
Sbjct: 528  GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587

Query: 568  RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627
             GPQGP G+ GPPG  G PG +G  G  G RG          PG+ G  G +G  G +G+
Sbjct: 588  VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARG---------MPGQTGPKGDRGFDGLAGL 638

Query: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687
             G +G +GD GP+GPPG PG     +G +G+ G  GPRG  G PGP G  GP GP G  G
Sbjct: 639  PGEKGHRGDPGPSGPPGPPGD----DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPG 694

Query: 688  PPGLQGLRGK---KGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPG 744
            PPG+ G+ G+   KG++GP G PG  G QG PG  G+PGP G  G PG  G +G PG PG
Sbjct: 695  PPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPG 754

Query: 745  PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804
             PG  GPPG  G  GPPG  G +G PG +G  G PG  G++G  G +GL G  GEKGE G
Sbjct: 755  MPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG 814

Query: 805  LPGAPGFPGVRGEKGD---QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP 861
             PG  G  G++G++G+    G +GE G  G KG  G  G+ GP GPPG  G   +    P
Sbjct: 815  FPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGV-PGLP 873

Query: 862  RMPGEQGPKGEKGDPGLPG---EPGLQGRPGELGPQG---PTGPPGAKGQEGAHGAPGAA 915
              PG QGPKG  G PG PG   E G +G PG+ GP+G   PTGP G +G  G  G PG  
Sbjct: 874  GYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK 933

Query: 916  GNPGAPGHVGAPG---PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972
            GN G  G  G PG   P+GP G  G PG +G PG  G+ G  G  G+ G  G  G  G P
Sbjct: 934  GNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 993

Query: 973  GAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPG 1031
            G PG+ GP G  G+ G  G RG PG PGP                        G++G PG
Sbjct: 994  GPPGVVGPQGPTGETGPMGERGHPGPPGP-----------------------PGEQGLPG 1030

Query: 1032 IPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGP 1091
            + G  G++GDPG   AG PG  GPPG +G PG RGLPG  G  G  G +G PG PG  G 
Sbjct: 1031 LAGKEGTKGDPG--PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 1092 PGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 1151
            PG+ G +    P  I            PG PG  G PG  G+KG PG+ G +G  G+ G 
Sbjct: 1089 PGERGPAGAAGPIGI------------PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGL 1136

Query: 1152 AGPPGLPGPPGIAGPQGSQGERGADGEVGQKG------DQGHPGVPGFMGPPGNPGPPGA 1205
             GP GLPGP G  GP G  G++G  GE GQKG      +QG PG  G  GP G PGP GA
Sbjct: 1137 QGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGA 1196

Query: 1206 DGIAGAAGPPGIQGSPGKEGP------PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGK 1259
            DG  G  G  G+ G  G EGP      PGP G  GLPG PGE+G+ G  G+ GPPG PG 
Sbjct: 1197 DGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP 1256

Query: 1260 AGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGP 1319
             G  G PG +G +GPPG  G+ G  G  G  GE+G  GLPG+ G PG  G+ G  G  GP
Sbjct: 1257 RGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP 1316

Query: 1320 QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGK 1379
             G  GPPG  G PG   + GP G+PG  G  G+ G PG PG  G  GPPG+ G+ G PG+
Sbjct: 1317 SGAAGPPGPKGPPG---DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQ 1373

Query: 1380 EGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 1439
             G PG  GEPG  G        G +GPPG  G  G  G  G KG  GL GP   PG+ GP
Sbjct: 1374 TGSPGPTGEPGPSGP------PGKRGPPGPAGPEGRQGEKGAKGEAGLEGP---PGKTGP 1424

Query: 1440 VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 1499
            +GP G PG+PG  GLRG           I   +G+Q           +P +      G P
Sbjct: 1425 IGPQGAPGKPGPDGLRG-----------IPGPVGEQ----------GLPGS--PGPDGPP 1461

Query: 1500 GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------V 1552
            GP GPPG  GL G +GP GE G PG  GL GP G  G KG+RG  G  G+ G        
Sbjct: 1462 GPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT 1521

Query: 1553 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            G  G +GPPG PG PG PG    G  G  GP G  G AGHPG PGPPGPPG+
Sbjct: 1522 GPSGPIGPPGPPGLPGPPG--PKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score =  846 bits (2186), Expect = 0.0
 Identities = 564/1460 (38%), Positives = 690/1460 (47%), Gaps = 213/1460 (14%)

Query: 281  TEDVFP-QGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNA 339
            T+ ++P    P++++ +TT + +K S+    ++  + ++  I Q+ + L      +  + 
Sbjct: 87   TKQLYPASAFPEDFSILTTVKAKKGSQA---FLVSIYNEQGIQQIGLELGRSPVFLYEDH 143

Query: 340  VGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEEREN--ID 397
             G        +FRG    +L D  WH++ALS+  +NV+L +DC    T  ++  ++  ID
Sbjct: 144  TGKPGPEDYPLFRGI---NLSDGKWHRIALSVHKKNVTLILDCKKKTTKFLDRSDHPMID 200

Query: 398  IQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPP 457
            I G  V G R+ D    + D+Q+++   D R A     C+  S  C   V     P  P 
Sbjct: 201  INGIIVFGTRILDEEVFEGDIQQLLFVSDHRAAY--DYCEHYSPDCDTAV-----PDTPQ 253

Query: 458  QRPPTPG---SEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP----------KGDIGAI 504
             + P P    +E  G  +T     P  E  E     P     P            ++   
Sbjct: 254  SQDPNPDEYYTEGDGEGETYYYEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPT 313

Query: 505  GPVGAPGPK-----GEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE--PGELG 557
                AP P+     G++ DVGIG +      +  +     P   D      GE  P +  
Sbjct: 314  PTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYT-----PSPYDDLTYGEGEENPDQPT 368

Query: 558  EPGLPGEVGMR-GPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
            +PG   E+            P PP   GA  L+GE  E+  R    E   D +       
Sbjct: 369  DPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRN-LDENYYDPYYDPTSSP 427

Query: 617  GQQGRPGPS-------GVAGPQGEKGDVGPAGPPGV--PGSVVQQEGLKGEQGAPGPRGH 667
             + G   P+       G+ GP+GEKG     G P +  PG +++        G PGP G 
Sbjct: 428  SEIGPGMPANQDTIYEGIGGPRGEKGQ---KGEPAIIEPGMLIE--------GPPGPEGP 476

Query: 668  QGAPGPPGARGP---IGPEGRDGPPGLQGLRGKKGDMGPPGI------------------ 706
             G PGPPG  GP   +G  G  GPPG  GL G  G  GPPG                   
Sbjct: 477  AGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKG 536

Query: 707  ---------------PGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP 751
                              L L+GP GP G+ G PGP G PG  G     G+PG  GP GP
Sbjct: 537  PMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGG---LKGEPGDVGPQGP 593

Query: 752  PGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA--- 808
             G  GP GP G PG +G  G  G  G+PG+ G +G+ G  GLAG PGEKG  G PG    
Sbjct: 594  RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653

Query: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF-TPHPR----M 863
            PG PG  GE+GD GE G  GLPG  G RG  G  GP GPPG PG T +   P P+     
Sbjct: 654  PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713

Query: 864  PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGH 923
             GE GP G++G+PG  G PG QG  G  G +GP G PG  G  GA G PG  G  G PG 
Sbjct: 714  QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773

Query: 924  VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG------PVGPRGDPGAPGL 977
             G  GP GP G +G PG RG  G DG RG KG  GE+G  G       +G +GD G  G 
Sbjct: 774  KGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGP 833

Query: 978  PGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGK--VRGSENCALGGQCVKGDRGAPGIPG 1034
            PGP G+ G +G  G  G  G PGPLG     GK  V G      G Q  KG  G PG PG
Sbjct: 834  PGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYP-GRQGPKGSIGFPGFPG 892

Query: 1035 SPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPG 1093
            + G +G  G  G  GP G  GP G +G  G RG+ G PGP+G +G DG  G PGERGP G
Sbjct: 893  ANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNG 952

Query: 1094 KPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPG---------FKGDKGVPGKPGREG 1144
              G +    P              PPGPPG  GLPG         F+G  G PG PG  G
Sbjct: 953  PQGPTGFPGPKG------------PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVG 1000

Query: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 1204
             +G  GE GP G  G PG  GP G QG  G  G+ G KGD G  G+PG  GPPG  G PG
Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPG 1060

Query: 1205 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264
              G+ G  G  G++G+ G  GPPGP G  G  G  G  G  G  G+PGP G PG AGE G
Sbjct: 1061 DRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKG 1120

Query: 1265 LPGPEGARGPPGFKGHTGDSGAPGPRG---------ESGAMGLPGQEGLPGKDGDTGPTG 1315
             PG +G +GP G  G  G  G PGP G         + G +G PGQ+G  G  G+ GP G
Sbjct: 1121 APGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPG 1180

Query: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375
            P GPQGP G PG +G+ G PG  G  G  GQKG +G  G PG PG +G +G PG PGEKG
Sbjct: 1181 PTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKG 1240

Query: 1376 VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPG------------DPGIPGHKG 1423
              G  G  G PG PG +G  G PG  G +GPPGG G PG            +PG+PG  G
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG 1300

Query: 1424 HTGLMGPQGLPGENGP---VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL 1480
              G  G +G  GE+GP    GPPGP G PG  G +G SP                     
Sbjct: 1301 PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG-SPG-------------------- 1339

Query: 1481 AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG------------RAGPMGEPGRPGQGGL 1528
                    P       G PG PGP G+DG PG              GP GEPG  G  G 
Sbjct: 1340 --------PVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGK 1391

Query: 1529 EGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET 1587
             GP GP GP+G +G KG  G  G+ G  G+ GP G  G PG+PG   DGL GIPGP GE 
Sbjct: 1392 RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPG--PDGLRGIPGPVGEQ 1449

Query: 1588 GPAGHPGLPGPPGPPGQCDP 1607
            G    PG PGP GPPG   P
Sbjct: 1450 GL---PGSPGPDGPPGPMGP 1466



 Score =  817 bits (2110), Expect = 0.0
 Identities = 490/1097 (44%), Positives = 554/1097 (50%), Gaps = 113/1097 (10%)

Query: 448  VTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA--GEKGEMGVAGPM------------- 492
            V +P    PP RP  PG++ +          P   G  G+ G  GPM             
Sbjct: 492  VGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQ 551

Query: 493  -------GLPGPKGDIGAIGPVGAPGPKGEKGDVG-IGPFG-QGEKGEKGSLGLPGPPGR 543
                   G  GP G  G  GPVG PG  G KG+ G +GP G +G +G  G  G PG  GR
Sbjct: 552  QARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGR 611

Query: 544  DGSKGMRGEPGELGEPG---------LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGE 594
             GS G RG PG+ G  G         LPGE G RG  GP G PGPPG  G  G  GE G 
Sbjct: 612  AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGP 671

Query: 595  KGTRGEKGERGL------DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
            +G  GE G RGL       G PG PG TG  G+PGP G  GPQGE G  G  G PG  G 
Sbjct: 672  RGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQG- 730

Query: 649  VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPG 708
            +   +G  G  G  GP G  G PG PGA GP G  G++GPPG +G +G  G  GP G PG
Sbjct: 731  LPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPG 790

Query: 709  LLGLQGPPGPPGVPGPPGPGGSPGLPG------------EIGFPGKPGPPGPTGPPGKDG 756
              G++G  G  G+ G  G  G  G PG            EIG PG  G  GP GP G+ G
Sbjct: 791  PRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGG 850

Query: 757  PNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
            PNG PGP G  GE G+ G  GLPG PG +G  G  G  G PG  GE G  G PG PG RG
Sbjct: 851  PNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRG 910

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAG---PAGPPGLPGTTSLFTPHPRMPGEQGPKGEK 873
            ++G  G +GE G  G+ G  G KG +G   PAGPPG  G      P    PG +GP G  
Sbjct: 911  QRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP-TGFPGPKGPPGPP 969

Query: 874  GDPGLPGEPGLQGR------------PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAP 921
            G  GLPG PG +G             PG +GPQGPTG  G  G+ G  G PG  G  G P
Sbjct: 970  GKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029

Query: 922  GHVGA------PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 975
            G  G       PGP+G PG  G PGLRG PG  G  G  GA G +G+ GP GP G  G+P
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089

Query: 976  GLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA----------------- 1017
            G  GP G  G  G PG  G  G PGP G K A G+ +G +  A                 
Sbjct: 1090 GERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGE-KGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077
            +G     GD+G  G PG  GS+GD G    GPPGP+GP G  G PG  G  G PGP+G  
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKG--EQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206

Query: 1078 GRDGAPGNPGERG---PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL---PGLPGFK 1131
            G  G  G+ G RG   PPG  GL  L  P        DV    PPGPPG     G PG  
Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD 1266

Query: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191
            G +G PG  G  G  G+KGE G  G PG PG  GP G +GERG  GE G  G  G     
Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG----- 1321

Query: 1192 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251
                PPG  GPPG DG  G+ GP G  G PG  G PGP G  G PG  G++G+ G+ G P
Sbjct: 1322 ----PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP 1377

Query: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311
            GP GEPG +G PG  GP G  GP G +G  G  G  G  G  G  G  G +G PGK G  
Sbjct: 1378 GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD 1437

Query: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371
            G  G  GP G +G PG  G  G PG  GP G PG KG  G  G  G PG +G  GPPGE 
Sbjct: 1438 GLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQ 1497

Query: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431
            GEK   G  G+PG  G  G KGE+G  G  G  GPPG  G PG PG  G KG +G  GP+
Sbjct: 1498 GEK---GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPK 1554

Query: 1432 GLPGENGPVGPPGPPGQ 1448
            G  G  GP GPPGPPG+
Sbjct: 1555 GEAGHPGPPGPPGPPGE 1571



 Score =  773 bits (1996), Expect = 0.0
 Identities = 441/918 (48%), Positives = 502/918 (54%), Gaps = 85/918 (9%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFGQ-GEKGEKGSLG 536
            P G  G  GV G  G PGPKG++G  G  G PG +G  G  G+ GP G  G  GEKG LG
Sbjct: 689  PPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLG 748

Query: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596
             PG PG  G+ G  G PG+ G PG  G  G  GPQGP G PGP G  GA G+   RG KG
Sbjct: 749  KPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGI---RGLKG 805

Query: 597  TRGEKGERGLDGFPGK---PGDTGQQGRPGPSGVAGPQGEKG------DVGPAGPPGVPG 647
            T+GEKGE G  GF G     GD G+ G PGP G  GP+G KG      D GP GPPG  G
Sbjct: 806  TKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKG 865

Query: 648  SV-----------------VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690
             +                 +   G  G  G  G RG  G PGP G RGP GP G  GP G
Sbjct: 866  KLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925

Query: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
            + G  G KG+ G  G  G  G +GP GP G  G PGP G PG PG+ G PG PG  G TG
Sbjct: 926  ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985

Query: 751  PPGKDGPNGPPG---PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE---AG 804
              GK GP GPPG   P G  GE G  GE G PG PG  GE G  GLAG+ G KG+   AG
Sbjct: 986  FQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG 1045

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH--PR 862
            LPG  G PG+RG  GD+G  G +G  GLKG+ G  G  GPAG PG  G      P   P 
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 863  MPGEQGPKGEKGDPGLPGEPG---------LQGRPGELGPQGPTGPPGAKGQEGAHGAPG 913
             PG QGP G  G+ G PGE G         LQG  G  GP GP GPPG  G +G  G PG
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 914  AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP---VGPRG 970
              G+ G  G  G PGP+GP G +G PG  G  G+ G RG++G  G++G  GP    GP G
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 971  DPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029
              G  GLPGPPG KG+ G+ G  G PG PGP G   A G   G +    G     G+ GA
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPG-ADGPQGPPGG----IGNPGA 1280

Query: 1030 PGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGE 1088
             G  G PG  G+PG+ G  GPPGP G  G+KG  G  G  G PGP+GP G DG  G+PG 
Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 1089 RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGK 1148
             G PG PG      PG+             PGP G  G PG KGD G PG+ G  G  G+
Sbjct: 1341 VGFPGDPG-----PPGE-------------PGPAGQDGPPGDKGDDGEPGQTGSPGPTGE 1382

Query: 1149 KGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI 1208
             G +GPPG  GPPG AGP+G QGE+GA GE G +G  G  G  G  G PG PGP G  GI
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGI 1442

Query: 1209 AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPG------PPGEPGKAGE 1262
             G  G  G+ GSPG +GPPGP GP GLPG+ G+ G +G  G PG      PPGE G+ G+
Sbjct: 1443 PGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGD 1502

Query: 1263 PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP 1322
             GLPGP+G+ GP G +G TG SG  GP G  G   LPG  G  G  G +GPTGP+G  G 
Sbjct: 1503 RGLPGPQGSSGPKGEQGITGPSGPIGPPGPPG---LPGPPGPKGAKGSSGPTGPKGEAGH 1559

Query: 1323 RGPPGKNGSPGSPGEPGP 1340
             GPPG  G PG   +P P
Sbjct: 1560 PGPPGPPGPPGEVIQPLP 1577



 Score =  620 bits (1598), Expect = e-177
 Identities = 396/938 (42%), Positives = 455/938 (48%), Gaps = 141/938 (15%)

Query: 748  PTGPPGKDGPNGPPGPPGT--KGEPGERGEDGLPGKPGLRGEIGEQGLA--GRPGEKGEA 803
            PT  P + GP G P    T  +G  G RGE G  G+P     I E G+   G PG +G A
Sbjct: 423  PTSSPSEIGP-GMPANQDTIYEGIGGPRGEKGQKGEPA----IIEPGMLIEGPPGPEGPA 477

Query: 804  GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 863
            GLPG PG  G  G+ GD         PG +G  G  G  G  G PG PGT  +    P  
Sbjct: 478  GLPGPPGTMGPTGQVGD---------PGERGPPGRPGLPGADGLPGPPGTMLML---PFR 525

Query: 864  PGEQGPKGEKGDPGLPGEPGLQG--RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAP 921
             G  G  G KG      E   Q   +   L  +GP GP G  G+ G  G PG+ G  G P
Sbjct: 526  FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEP 585

Query: 922  GHVGAPGP---SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 978
            G VG  GP    GPPG  G PG RG  G DG RG          PG  GP+GD G  GL 
Sbjct: 586  GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARG---------MPGQTGPKGDRGFDGLA 636

Query: 979  GPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037
            G PG KG  G+PG  G PG PG  G +   G+V                 G  G+PG PG
Sbjct: 637  GLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEV-----------------GPRGLPGEPG 679

Query: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097
             RG   +G  GPPGP GPPG  G  G  G  G  GPQG  G  G  GNPG +G PG  G 
Sbjct: 680  PRGL--LGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQG- 736

Query: 1098 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157
             ++  PG+              GP G PGLPG  G  G PG PG+EG  G+KG  GPPG 
Sbjct: 737  -AIGPPGE-------------KGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGP 782

Query: 1158 PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG---------NPGPPGADGI 1208
             GP G  GP+G +G  G  G  G KG++G  G PGF G  G          PGP G DG 
Sbjct: 783  QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGP 842

Query: 1209 AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE------ 1262
             G  G  G  G PG  GPPG +G  G+PG+PG  G++G  G  G PG PG  GE      
Sbjct: 843  EGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGT 902

Query: 1263 PGLPGPEGARGPPGFKGHTGD---SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGP 1319
            PG PGP G RGP G +G  G    +G PGP+G SG  G  G  G  G +G  GPTG  GP
Sbjct: 903  PGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGP 962

Query: 1320 QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGK 1379
            +GP GPPGK+G PG PG+ G      + G +G+ G PG PG +GP+GP GE G  G  G 
Sbjct: 963  KGPPGPPGKDGLPGHPGQRG------ETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH 1016

Query: 1380 EGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 1439
             G PG PGE G  G  G  G KGD GP G  G+ G PG+ G  G  GL GP G  G  G 
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGN 1076

Query: 1440 VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 1499
             GPPGPPG  G PG RG + +   +   I    G Q             PA  K + G  
Sbjct: 1077 EGPPGPPGPAGSPGERGPAGAAGPIG--IPGRPGPQ---------GPPGPAGEKGAPGEK 1125

Query: 1500 GPPGPPGKDGL------PGRAGPMGEPGR---------PGQGGLEG------------PS 1532
            GP GP G+DGL      PG AGP+G PG          PGQ G +G            P 
Sbjct: 1126 GPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQ 1185

Query: 1533 GPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETG 1588
            GPIG  G  GA G+PG  G     G +G+ GP G PG PG  G     L G+PGP GE G
Sbjct: 1186 GPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG-----LQGLPGPPGEKG 1240

Query: 1589 PAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
              G  G  GPPGPPG   PS           PG +  P
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNP 1278


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  916 bits (2368), Expect = 0.0
 Identities = 588/1448 (40%), Positives = 701/1448 (48%), Gaps = 216/1448 (14%)

Query: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340
            T  +FP G P +++ +T  R R   +     +  +     + Q+ + L    + +  +  
Sbjct: 72   TRQLFPGGFPKDFSLLTVVRTRPGLQAP---LLTLYSAQGVRQLGLELGRPVRFLYEDQT 128

Query: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDI 398
            G  +   + VFRG     L D  WH++A++++ Q+V+L +DC   + + LP   R  +D 
Sbjct: 129  GRPQPPSQPVFRGL---SLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDT 185

Query: 399  QGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETC----CDIPSGPCQVTVVTEP--- 451
             G  + G R+ D    + D+Q + I      A  E+C     +   G  +     +P   
Sbjct: 186  HGVIIFGARILDEEVFEGDVQELAIV-PGVQAAYESCEQKELECEGGQRERPQNQQPHRA 244

Query: 452  --PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVA-------------GPMGLPG 496
               P   P R   P +++             GEKGE  V              GP GL G
Sbjct: 245  QRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG 304

Query: 497  PKGDIGAIGPVGAPGPKGEKGDVGI-------GP------------FGQGEKG------- 530
            P G  G  GPVG PG +G  G  G+       GP             G G+KG       
Sbjct: 305  PPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQE 364

Query: 531  -------EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP------GEVGMRGPQGPPGLP 577
                   ++  L L GPP   G  G  G PG LG+PG P      G++G +GP+GP GL 
Sbjct: 365  AQAQAILQQARLALRGPP---GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421

Query: 578  GPP---GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP---Q 631
            GPP   GR G  G  G RG  G  G KG+RG DG PG PG+ G +G  G  G+ GP    
Sbjct: 422  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481

Query: 632  GEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGL 691
            GE+GD G  GP G+PG               GPRG  G  GPPG  GP G  G DGP G 
Sbjct: 482  GERGDDGEIGPRGLPGE-------------SGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 528

Query: 692  QGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPGGSPGLPGEIGFPGKPGPPGP 748
            +G  G +G+ GPPG  G  G QG PGP G  GP    GP G PGLPG  G  G PG PG 
Sbjct: 529  KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 588

Query: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP-- 806
             GPPG  G  GP GP G  G PG RG  G+ G  GL+G  GE+G  G PG KG+ G+   
Sbjct: 589  EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 648

Query: 807  -GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPG 865
             G  G PG RGE G +G KG  G  G  G  G  GE G  G PGLPG           PG
Sbjct: 649  RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG----------YPG 698

Query: 866  EQGPKGEKGDPGLPGEP------GLQGRPGELGPQGPTGPPGAKGQEGA----------- 908
             QGPKG  G PG PG        GL G+ G  G +GPTGP G +G  GA           
Sbjct: 699  RQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSG 758

Query: 909  ----HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
                HG PG  G PG  G  G PGP GPPG  G  GL G PG+ GE G +G  G  G PG
Sbjct: 759  GDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 818

Query: 965  PVGPR---------GDPGAPGLPGPPGK----GKDGEPGLRGSPGLPGPLGTKAACGKVR 1011
             VGP+         G+ G PG PGPPG+    G  G+ G +G PG PG  G     G +R
Sbjct: 819  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG-LR 877

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSR---GLP 1068
            G            G+RG PG  G PG +G+   G +GPPGP+G PG++G+ GS    G P
Sbjct: 878  G----------FPGERGLPGTAGGPGLKGNE--GPSGPPGPAGSPGERGAAGSGGPIGPP 925

Query: 1069 GFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLP 1128
            G PGPQGP G  G  G PGE+GP G  G   +  P  +            PGP G PG+ 
Sbjct: 926  GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL------------PGPAGPPGVA 973

Query: 1129 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188
            G  GDKG  G PG++GT+G KGE GP   PGPPG  GP G  G  GADGE G +G QGH 
Sbjct: 974  GEDGDKGEVGDPGQKGTKGNKGEHGP---PGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1030

Query: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248
            G  G  G  G  GPPG  G+ G  GP G +G  G  GP GP GP   PG  G  G  G D
Sbjct: 1031 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP---PGPRGPAGPNGAD 1087

Query: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308
            G  GPPG  G  G PG  G  G  G PG +   G+ G  GPRGE G  G  GQ G PG  
Sbjct: 1088 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQ---GEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368
            G  GPTG  GP+G  GP G  G PG PGE GP G  G KG +GE+G PG PG  GP G  
Sbjct: 1145 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1204

Query: 1369 GEPGEKGVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKGQPGDPGIPGHKGHT 1425
            G PG  G  G  G PG  G  G KG +GDP   G  G  GP G  G  G PG  G +G  
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLP 1264

Query: 1426 GLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA 1485
            G +G QG PG  G  GPPGP G PG PGLRG++ +            G++    L  L+ 
Sbjct: 1265 GSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK-----------GEKGHPGLIGLIG 1313

Query: 1486 QMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKG 1545
              PP      QG  G  G PG  G PG+ G MG PG  G  G  GP G  GP G +GAKG
Sbjct: 1314 --PP----GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1367

Query: 1546 DPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP---------GIPG----PQGETGPAGH 1592
              G PG G +GE G  G PG PG PG     LP          + G     + E  P G 
Sbjct: 1368 ATG-PG-GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG- 1424

Query: 1593 PGLPGPPG 1600
             G PG PG
Sbjct: 1425 -GAPGSPG 1431



 Score =  780 bits (2014), Expect = 0.0
 Identities = 495/1188 (41%), Positives = 575/1188 (48%), Gaps = 187/1188 (15%)

Query: 568  RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627
            R PQ  P     P     P  Q   G +G +GEKGE  +     +PG            V
Sbjct: 246  RSPQQQPSRLHRPQNQ-EPQSQAAHGPRGLKGEKGEPAVL----EPGML----------V 290

Query: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687
             GP G +G  G  GPPG+             QG PGP G  G  GPPG  G  G +G  G
Sbjct: 291  EGPPGPEGPAGLIGPPGI-------------QGNPGPVGDPGERGPPGRAGLPGSDGAPG 337

Query: 688  PPGLQGLRGKK-----GDMGPPGIP-----------GLLGLQGPPGPPGVPGPPGPGGSP 731
            PPG   +   +     GD GP                 L L+GPPGP G  G PGP G P
Sbjct: 338  PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 397

Query: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791
            G PG  G  G  GP GP GP G     GPPG  G +G  G  G  G+PG PG++G+ G  
Sbjct: 398  GSPGLKGESGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFD 454

Query: 792  GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP 851
            GL G PGEKG  G  GA G PG  GE G++G+ GE+G  GL G+ G +G  GP GPPG+P
Sbjct: 455  GLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP 514

Query: 852  GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG---PQGPTGPPGAKGQEGA 908
            G   +      M G QGPKG  G  G PG PG QG PG  G   PQG  GP G KG +G 
Sbjct: 515  GPPGV----RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGK 570

Query: 909  HGAPGAAGNPGAPGHVGAPGP---------SGPPGSVGAPGLRGTPGKDG---------- 949
             G PG  G+ G PGH G  GP         SGP G +G PG RG  G DG          
Sbjct: 571  PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 630

Query: 950  -----------------ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDGE 988
                             +RGE G  G  G  GP GP+G  G  G PGPPG    KGK G 
Sbjct: 631  KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 690

Query: 989  PGLRGSPGLPGPLGTKAACGKVRGS-ENCALGGQCVKGDRGAPGIPGSPGSRGDPGI--- 1044
            PGL G PG  GP G+    G    S E  A G     G RG  G  G  G RG  G    
Sbjct: 691  PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 750

Query: 1045 ----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPGNPGERG------- 1090
                G +G  GP GPPG++G PG +G  GFPGP+GP G   +DG PG+PG+RG       
Sbjct: 751  SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK 810

Query: 1091 --PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF------KGDKGVPGKPGR 1142
              PPG PG+              +  +  PPGPPG  GLPG       KGD G PG PG+
Sbjct: 811  TGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870

Query: 1143 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP 1202
            +G  G +G  G  GLPG  G  G +G++G  G  G  G  G++G  G  G +GPPG PGP
Sbjct: 871  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 930

Query: 1203 PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI------------------PGEEGK 1244
             G  G AG  G PG +G  G  G  G QGP GLPG                   PG++G 
Sbjct: 931  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 990

Query: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG---------PRGESGA 1295
            +G  G+ GPPG PG  G  G PG  GA G PG +G  G  GA G         P G  G 
Sbjct: 991  KGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGL 1050

Query: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQKGSKGE 1352
             GLPG  G  G+ GD GP GP GP GPRGP G NG+ G  G PG  G    PG+KG  GE
Sbjct: 1051 QGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGE 1110

Query: 1353 NGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQ 1412
            +GSPG+ G  G +GP GE GEKG   + G PG+PG PG KG  GD G KG+ GP G  G 
Sbjct: 1111 SGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGD 1167

Query: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE-----SPSMETLRRL 1467
            PG PG  G +G  G  G +G  GE G  G PGP G+ G PG  G+     SP  E     
Sbjct: 1168 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR--- 1224

Query: 1468 IQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG 1527
             Q   G + +        +  P       G  GP G PG DGL G  G +G+ GRPG  G
Sbjct: 1225 -QGGKGAKGDPGAIGAPGKTGPV------GPAGPAGKPGPDGLRGLPGSVGQQGRPGATG 1277

Query: 1528 LEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGPQGE 1586
              GP GP+GP G  G +GD GA     +GE G PG+ G  G PG   + G  G+PGPQG 
Sbjct: 1278 QAGPPGPVGPPGLPGLRGDAGA-----KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS 1332

Query: 1587 TGPAGHPGLP---------GPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
             G  G  G+P         GPPG PG   P      A  A  PG  KG
Sbjct: 1333 PGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG----AKGATGPGGPKG 1376



 Score =  441 bits (1134), Expect = e-123
 Identities = 274/654 (41%), Positives = 318/654 (48%), Gaps = 75/654 (11%)

Query: 1021 QCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG---FPGPQGPA 1077
            Q   G RG  G  G P    +PG+ V GPPGP GP G  G PG +G PG    PG +GP 
Sbjct: 266  QAAHGPRGLKGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 324

Query: 1078 GRDGAPGNPGERGPPGK----------------PGLSSLLSPGDINLLAKDVCNDCPPGP 1121
            GR G PG+ G  GPPG                 P +++  +     L    +    PPGP
Sbjct: 325  GRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP 384

Query: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG---SQGERGADGE 1178
             G  G PG  G  G PG  G  G  G +G  GP GL GPPG AG +G   + G RG  G+
Sbjct: 385  MGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 444

Query: 1179 VGQKGDQGHPGVPGFMGPPGN---------PGPPGADGIAGAAGPPGIQGSPGKEGPPGP 1229
             G KGD+G  G+PG  G  G+         PGPPG DG  G  G  G +G PG+ GP G 
Sbjct: 445  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 504

Query: 1230 QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---RGPPGFKGHTGDSGA 1286
             GP G PGIPG  G  G DG  GP G  G  GEPG PG +G    +G PG +G  G  G 
Sbjct: 505  LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGE 564

Query: 1287 PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ 1346
             GP+G+ G  G+PG +G PG  G  GP G +G QGP GP G  G PG  G  G  G  G 
Sbjct: 565  KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 624

Query: 1347 KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP 1406
            KG KGE G  G PGF G  G  G+ GE GVPG  G  G  G  G  G  GDPG  G  G 
Sbjct: 625  KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGE 684

Query: 1407 PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRR 1466
             G  G PG PG PG +G  G +G  G PG +G  G  G  G+ G  G RG  P+    +R
Sbjct: 685  KGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG--PTGPRGQR 742

Query: 1467 LIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG 1526
              +   GK               +  K + G  GP GPPG+ GLPG  GP G PG     
Sbjct: 743  GPRGATGK---------------SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPG----- 782

Query: 1527 GLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKD-------GLP 1578
                P GP GP G+ G  G PG  G VG +G+ GPPG PG  G  G A +       G P
Sbjct: 783  ----PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 1579 GIPGPQGE------TGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            G PGP GE       G  G  G PGPPG PG+  P+    F      PG   GP
Sbjct: 839  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGP 892


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  902 bits (2332), Expect = 0.0
 Identities = 578/1463 (39%), Positives = 706/1463 (48%), Gaps = 225/1463 (15%)

Query: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340
            T  +FP G P +++ +T  R R   +     +  +     + Q+ + L    + +  +  
Sbjct: 72   TRQLFPGGFPKDFSLLTVVRTRPGLQAP---LLTLYSAQGVRQLGLELGRPVRFLYEDQT 128

Query: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDI 398
            G  +   + VFRG     L D  WH++A++++ Q+V+L +DC   + + LP   R  +D 
Sbjct: 129  GRPQPPSQPVFRGL---SLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDT 185

Query: 399  QGKTVIGKRLYDSVPIDFDLQRIVIY---------CDSRHAELETCC-DIP--------- 439
             G  + G R+ D    + D+Q + I          C+ +  E E    + P         
Sbjct: 186  HGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQ 245

Query: 440  -SGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
             S   Q + +  P    P  + PTPG E+              E  E  +  P+      
Sbjct: 246  RSPQQQPSRLHRPQNQEPQSQDPTPGEEE--------------EILESSLLPPL------ 285

Query: 499  GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558
             +  A GP G  G KGE   +  G   +G  G +G  GL GPPG  G+ G  G+PGE G 
Sbjct: 286  -EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344

Query: 559  P---GLPGEVG-------------------------------------------MRGPQG 572
            P   GLPG  G                                           +RGP G
Sbjct: 345  PGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404

Query: 573  P---PGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629
            P    G PGP G+ G+PGL+GE G+ G +G +G +GL G PGK G  G+ G  G  G+ G
Sbjct: 405  PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 464

Query: 630  PQGEKGDVGPAGPPGVPGSVVQ--------------QEGLKGEQGAPGPRGHQGAPGPPG 675
              G KGD G  G PG+PG                  ++G +G+ G  GPRG  G  GP G
Sbjct: 465  DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 524

Query: 676  ARGPIGPEGRDGPPGLQGL---RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732
              GP GP G  GPPG++G+   +G KG +GP G PG  G QG PG  G+PGP G  G  G
Sbjct: 525  LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 584

Query: 733  LPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQG 792
              G  G PG PG PG  GPPG  G  GPPG  G +G  G +G  G PG  G++G  G +G
Sbjct: 585  EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG 644

Query: 793  LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852
            L G  GEKGE G PG  G  GV+G++G+ G  G  G  G +G +G  G  G  GPPGL G
Sbjct: 645  LKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMG 704

Query: 853  TT-SLFTPH-PRMPGEQGPKGEKGDPGLPGEP------GLQGRPGELGPQGPTGPPGAKG 904
                L  P  P  PG QGPKG  G PG PG        GL G+ G  G +GPTGP G +G
Sbjct: 705  EKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRG 764

Query: 905  QEGA---------------HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDG 949
              GA               HG PG  G PG  G  G PGP GPPG  G  GL G PG+ G
Sbjct: 765  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 824

Query: 950  ERGEKGAAGEEGSPGPVGPR---------GDPGAPGLPGPPGK----GKDGEPGLRGSPG 996
            E G +G  G  G PG VGP+         G+ G PG PGPPG+    G  G+ G +G PG
Sbjct: 825  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPG 884

Query: 997  LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP 1056
             PG  G     G +RG            G+RG PG  G PG +G+   G +GPPGP+G P
Sbjct: 885  PPGAPGKDGPAG-LRG----------FPGERGLPGTAGGPGLKGNE--GPSGPPGPAGSP 931

Query: 1057 GDKGSPGSR---GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDV 1113
            G++G+ GS    G PG PGPQGP G  G  G PGE+GP G  G   +  P  +       
Sbjct: 932  GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL------- 984

Query: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173
                 PGP G PG+ G  GDKG  G PG++GT+G KGE GP   PGPPG  GP G  G  
Sbjct: 985  -----PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP---PGPPGPIGPVGQPGAA 1036

Query: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233
            GADGE G +G QGH G  G  G  G  GPPG  G+ G  GP G +G  G  GP GP GP 
Sbjct: 1037 GADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP- 1095

Query: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
              PG  G  G  G DG  GPPG  G  G PG  G  G  G PG +   G+ G  GPRGE 
Sbjct: 1096 --PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQ---GEPGVKGPRGER 1150

Query: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353
            G  G  GQ G PG  G  GPTG  GP+G  GP G  G PG PGE GP G  G KG +GE+
Sbjct: 1151 GEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1210

Query: 1354 GSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGK 1410
            G PG PG  GP G  G PG  G  G  G PG  G  G KG +GDP   G  G  GP G  
Sbjct: 1211 GEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPA 1270

Query: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
            G  G PG  G +G  G +G QG PG  G  GPPGP G PG PGLRG++ +          
Sbjct: 1271 GPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK--------- 1321

Query: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
              G++    L  L+   PP      QG  G  G PG  G PG+ G MG PG  G  G  G
Sbjct: 1322 --GEKGHPGLIGLIG--PP----GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1373

Query: 1531 PSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP---------GIP 1581
            P G  GP G +GAKG  G PG G +GE G  G PG PG PG     LP          + 
Sbjct: 1374 PPGLPGPAGPKGAKGATG-PG-GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVD 1431

Query: 1582 G----PQGETGPAGHPGLPGPPG 1600
            G     + E  P G  G PG PG
Sbjct: 1432 GSRLMQEDEAIPTG--GAPGSPG 1452



 Score =  778 bits (2009), Expect = 0.0
 Identities = 495/1193 (41%), Positives = 576/1193 (48%), Gaps = 194/1193 (16%)

Query: 580  PGRVGAPGLQGERGEKGTRGEK-----------------GERGLDGFPGKPGDTGQQGRP 622
            P R+  P  Q  + +  T GE+                 G RGL G  G+P        P
Sbjct: 252  PSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVL----EP 307

Query: 623  GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682
            G   V GP G +G  G  GPPG+             QG PGP G  G  GPPG  G  G 
Sbjct: 308  GML-VEGPPGPEGPAGLIGPPGI-------------QGNPGPVGDPGERGPPGRAGLPGS 353

Query: 683  EGRDGPPGLQGLRGKK-----GDMGPPGIP-----------GLLGLQGPPGPPGVPGPPG 726
            +G  GPPG   +   +     GD GP                 L L+GPPGP G  G PG
Sbjct: 354  DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG 413

Query: 727  PGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786
            P G PG PG  G  G  GP GP GP G     GPPG  G +G  G  G  G+PG PG++G
Sbjct: 414  PLGQPGSPGLKGESGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKG 470

Query: 787  EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 846
            + G  GL G PGEKG  G  GA G PG  GE G++G+ GE+G  GL G+ G +G  GP G
Sbjct: 471  DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKG 530

Query: 847  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG---PQGPTGPPGAK 903
            PPG+PG   +      M G QGPKG  G  G PG PG QG PG  G   PQG  GP G K
Sbjct: 531  PPGIPGPPGV----RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 586

Query: 904  GQEGAHGAPGAAGNPGAPGHVGAPGP---------SGPPGSVGAPGLRGTPGKDG----- 949
            G +G  G PG  G+ G PGH G  GP         SGP G +G PG RG  G DG     
Sbjct: 587  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 646

Query: 950  ----------------------ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----K 983
                                  +RGE G  G  G  GP GP+G  G  G PGPPG    K
Sbjct: 647  GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 706

Query: 984  GKDGEPGLRGSPGLPGPLGTKAACGKVRGS-ENCALGGQCVKGDRGAPGIPGSPGSRGDP 1042
            GK G PGL G PG  GP G+    G    S E  A G     G RG  G  G  G RG  
Sbjct: 707  GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 766

Query: 1043 GI-------GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPGNPGERG-- 1090
            G        G +G  GP GPPG++G PG +G  GFPGP+GP G   +DG PG+PG+RG  
Sbjct: 767  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 826

Query: 1091 -------PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF------KGDKGVP 1137
                   PPG PG+              +  +  PPGPPG  GLPG       KGD G P
Sbjct: 827  GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886

Query: 1138 GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP 1197
            G PG++G  G +G  G  GLPG  G  G +G++G  G  G  G  G++G  G  G +GPP
Sbjct: 887  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 946

Query: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI------------------P 1239
            G PGP G  G AG  G PG +G  G  G  G QGP GLPG                   P
Sbjct: 947  GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006

Query: 1240 GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG---------PR 1290
            G++G +G  G+ GPPG PG  G  G PG  GA G PG +G  G  GA G         P 
Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066

Query: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQK 1347
            G  G  GLPG  G  G+ GD GP GP GP GPRGP G NG+ G  G PG  G    PG+K
Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1126

Query: 1348 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPP 1407
            G  GE+GSPG+ G  G +GP GE GEKG   + G PG+PG PG KG  GD G KG+ GP 
Sbjct: 1127 GEPGESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1183

Query: 1408 GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE-----SPSME 1462
            G  G PG PG  G +G  G  G +G  GE G  G PGP G+ G PG  G+     SP  E
Sbjct: 1184 GFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSE 1243

Query: 1463 TLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR 1522
                  Q   G + +        +  P       G  GP G PG DGL G  G +G+ GR
Sbjct: 1244 GR----QGGKGAKGDPGAIGAPGKTGPV------GPAGPAGKPGPDGLRGLPGSVGQQGR 1293

Query: 1523 PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-YAKDGLPGIP 1581
            PG  G  GP GP+GP G  G +GD GA     +GE G PG+ G  G PG   + G  G+P
Sbjct: 1294 PGATGQAGPPGPVGPPGLPGLRGDAGA-----KGEKGHPGLIGLIGPPGEQGEKGDRGLP 1348

Query: 1582 GPQGETGPAGHPGLP---------GPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
            GPQG  G  G  G+P         GPPG PG   P      A  A  PG  KG
Sbjct: 1349 GPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG----AKGATGPGGPKG 1397



 Score =  441 bits (1135), Expect = e-123
 Identities = 274/661 (41%), Positives = 323/661 (48%), Gaps = 81/661 (12%)

Query: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG---F 1070
            E  A G + +KG++G P +        +PG+ V GPPGP GP G  G PG +G PG    
Sbjct: 286  EEAAHGPRGLKGEKGEPAVL-------EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD 338

Query: 1071 PGPQGPAGRDGAPGNPGERGPPGK----------------PGLSSLLSPGDINLLAKDVC 1114
            PG +GP GR G PG+ G  GPPG                 P +++  +     L    + 
Sbjct: 339  PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLA 398

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG---SQG 1171
               PPGP G  G PG  G  G PG  G  G  G +G  GP GL GPPG AG +G   + G
Sbjct: 399  LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 458

Query: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGN---------PGPPGADGIAGAAGPPGIQGSPG 1222
             RG  G+ G KGD+G  G+PG  G  G+         PGPPG DG  G  G  G +G PG
Sbjct: 459  ARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPG 518

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---RGPPGFKG 1279
            + GP G  GP G PGIPG  G  G DG  GP G  G  GEPG PG +G    +G PG +G
Sbjct: 519  ESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQG 578

Query: 1280 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
              G  G  GP+G+ G  G+PG +G PG  G  GP G +G QGP GP G  G PG  G  G
Sbjct: 579  AIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKG 638

Query: 1340 PSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPG 1399
              G  G KG KGE G  G PGF G  G  G+ GE GVPG  G  G  G  G  G  GDPG
Sbjct: 639  VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 698

Query: 1400 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 1459
              G  G  G  G PG PG PG +G  G +G  G PG +G  G  G  G+ G  G RG  P
Sbjct: 699  PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG--P 756

Query: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 1519
            +    +R  +   GK               +  K + G  GP GPPG+ GLPG  GP G 
Sbjct: 757  TGPRGQRGPRGATGK---------------SGAKGTSGGDGPHGPPGERGLPGPQGPNGF 801

Query: 1520 PGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKD--- 1575
            PG         P GP GP G+ G  G PG  G VG +G+ GPPG PG  G  G A +   
Sbjct: 802  PG---------PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGP 852

Query: 1576 ----GLPGIPGPQGE------TGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
                G PG PGP GE       G  G  G PGPPG PG+  P+    F      PG   G
Sbjct: 853  MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912

Query: 1626 P 1626
            P
Sbjct: 913  P 913



 Score =  231 bits (588), Expect = 6e-60
 Identities = 164/436 (37%), Positives = 185/436 (42%), Gaps = 107/436 (24%)

Query: 1218 QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277
            Q  P +   P  Q P      PGEE +E  +    PP E            E A GP G 
Sbjct: 249  QQQPSRLHRPQNQEPQSQDPTPGEE-EEILESSLLPPLE------------EAAHGPRGL 295

Query: 1278 KGHTGD----------SGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327
            KG  G+           G PGP G +G +G PG +G PG         P G  G RGPPG
Sbjct: 296  KGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPG---------PVGDPGERGPPG 346

Query: 1328 KNGSPGSPGEPGPSGT----PGQKGSKGENGSPGLPGF------------LGPRGPPGEP 1371
            + G PGS G PGP GT    P + GS G +  P +               L  RGPPG  
Sbjct: 347  RAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM 406

Query: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD---------------P 1416
            G  G PG  G   +PG PG KGE GD G +G +GP G  G PG                P
Sbjct: 407  GYTGRPGPLG---QPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 463

Query: 1417 GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 1476
            G PG KG  G  G  GLPGE G  G  G  G PG PG  GE                   
Sbjct: 464  GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE------------------- 504

Query: 1477 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 1536
                            +   G  GP G PG+ G  G  GP G PG PG  G+ G  GP G
Sbjct: 505  ----------------RGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 548

Query: 1537 PKGERGAKGDPGAPGV----GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGH 1592
            PKG  G +G+PG PG     G +G  GP G  G  GE G    G PG+PG  G  GP GH
Sbjct: 549  PKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG--PQGKPGLPGMPGSDGPPGH 606

Query: 1593 PGLPGPPGPPGQCDPS 1608
            PG  GPPG  G   PS
Sbjct: 607  PGKEGPPGTKGNQGPS 622



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 44/137 (32%), Positives = 51/137 (37%), Gaps = 22/137 (16%)

Query: 1485 AQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAK 1544
            AQ  P    S   RP    P  +D  PG    + E               + P  E  A 
Sbjct: 244  AQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESS-------------LLPPLEEAAH 290

Query: 1545 GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            G  G     L+GE G P +     EPG   +G PG  GP G  GP G  G PGP G PG+
Sbjct: 291  GPRG-----LKGEKGEPAVL----EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGE 341

Query: 1605 CDPSQCAYFASLAARPG 1621
              P   A        PG
Sbjct: 342  RGPPGRAGLPGSDGAPG 358


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  901 bits (2328), Expect = 0.0
 Identities = 574/1375 (41%), Positives = 664/1375 (48%), Gaps = 265/1375 (19%)

Query: 449  TEPPPPPPPQRPPTPGSE-------------QIGFLKTINCSCPAGEKGEMGVAGPMGLP 495
            +E   P  P +P +PG +               GF   +  +   GE+G  G AG  GLP
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 496  GPKGDIGAIGPVGAPGPKGEKGDVG----------IGPFGQGEKGEKGSLGLPGPPGRDG 545
            G  G  GA GP G PGP G +G+ G          +GP   G KGEKG +G  GP G  G
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATG 1569

Query: 546  SKGMRGEPGEL--GEPGLPGEVGMRGP------------QGPPGLPGPPGRVGAPGLQGE 591
             +G RG PG +  G+PG  G+ G RGP             GPPG  G PGR G PG  G 
Sbjct: 1570 VQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGP 1629

Query: 592  RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ 651
            RG  G  GEKG+ G  G PG PG  G++G  G  GV GP GEKGD G  G          
Sbjct: 1630 RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPG---------- 1679

Query: 652  QEGLKGEQGAPGPRGHQGAPGPPGARGPI---GP----EGRDGPPGLQGLRGKKGDMGPP 704
            ++G  G  G+ GP+G +G PGPPG  G +   GP    +G  G  G +G RG KGD G P
Sbjct: 1680 EDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLP 1739

Query: 705  GIPG---LLGLQGPPGPPGVPGPPGPGGS------PGLPGEIGFPGKPGPPGPTGPPGKD 755
            G PG   + G +GPPGP G PG  GP G       PGL G  G  GKPG  GP+GP   +
Sbjct: 1740 GAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGP---N 1796

Query: 756  GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVR 815
            G  G  G PG  G PG RGE GLPG  G  G  G+ G  G+PG  G+ G PG PG  G +
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 816  GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL-FTPHPRMPGEQGPKGE-- 872
            GEKGD G  G  G  G KG+RG  G  GP GPPGLPG         P +PG  GPKG+  
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRG 1916

Query: 873  ----KGDPGLPGEPGLQGRPGEL------------------------------------- 891
                KG+ GLPGE GL+G PG +                                     
Sbjct: 1917 ETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPER 1976

Query: 892  --------------GPQGPTGPPGAKGQEGAHGAPGAAGNPG-APGHVGAPGPSGPPGSV 936
                          G +GP G PG +G +G  G PG  G PG A G  G PGPSG  G  
Sbjct: 1977 RRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEP 2036

Query: 937  GAPGLRGTPGK---------DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----- 982
            G PG+ G PG+          GERGE+G  GE G  G  GP G PG PG PGPPG     
Sbjct: 2037 GKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSV 2096

Query: 983  -------KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI--- 1032
                    G+ G PGL+G+ G PG  G +   G          G   +KGDRG PG    
Sbjct: 2097 DEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD--------RGVPGIKGDRGEPGPRGQ 2148

Query: 1033 ---PGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN 1085
               PG PG RG  G     G+ GP GP GP G  G PG  G PG  GP GP G  G  G 
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208

Query: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL------PGLPGFKGDKGVPGK 1139
            PGE GPPG+ GL+     G + L         PPGP GL      PGLPG  G+ G PG 
Sbjct: 2209 PGETGPPGR-GLTG--PTGAVGLPG-------PPGPSGLVGPQGSPGLPGQVGETGKPGA 2258

Query: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ--------KGDQGHPG-- 1189
            PGR+G  GK G+ G PG+PG PG+ GP G +GE G  G  GQ        KG++G PG  
Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318

Query: 1190 ------VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
                   PG  G  G PGP G  G AG AG PG  G  G++G PGP+G  G PG+    G
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV----G 2374

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303
              G  G PGPPG  G  G PGLPG  G  G PG  G  G+ G PGP GE G  G PG+EG
Sbjct: 2375 VPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREG 2434

Query: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLG 1363
            +PG  G  GP G  GP G  G  G  G PG  G PGP G  G+ G +GE+G PG  G  G
Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRG 2493

Query: 1364 PRGPPGEPGEKGVPGKEGV----------------PGKPGEPGFKGERGDPGIKGDKGP- 1406
              GPPG  GE+G  G  G                 PG  G  G  GERG  G+ GDKGP 
Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPR 2553

Query: 1407 --------PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 1458
                     G KG+PGD G  G  G  GL+GPQG PG  G  G PG PG+ G PG+RGE 
Sbjct: 2554 GDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEK 2613

Query: 1459 PSMETLR-RLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPM 1517
              +  +  R ++ E G +    L               +G  G  GPPG+ GL G  G M
Sbjct: 2614 GDVGFMGPRGLKGERGVKGACGL------------DGEKGDKGEAGPPGRPGLAGHKGEM 2661

Query: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKDG 1576
            GEPG PGQ G  G  G IGPKG+RG  G PG  G  G +GE G PGI G PG  G   DG
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG--NDG 2719

Query: 1577 LPGIPGPQGETGPAGH-----------------------PGLPGPPGPPGQCDPS 1608
              G PGP G  GP G                        PG PG  G  G+  P+
Sbjct: 2720 SAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774



 Score =  900 bits (2326), Expect = 0.0
 Identities = 564/1301 (43%), Positives = 656/1301 (50%), Gaps = 187/1301 (14%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMG------VAGPM 492
            P+G   +  V   P    P+ PP P   Q             GEKGE G      V GP 
Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQ-------------GEKGEPGRPGDPAVVGPA 1548

Query: 493  --GLPGPKGDIGAIGPVGAPGPKGEKGDVGIG-PFGQGEKGEKGSLGLPGPPGRDGSKGM 549
              G  G KGD+G  GP GA G +GE+G  G+  P   G KG+ G  G  G  GR G  G 
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 550  RGEPGELGEPGL---PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL 606
             G PGE G+PG    PG VG RG  G  G  G  G  G PGL G+ GE+G RG  G RG 
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668

Query: 607  DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPG---VPGSVVQQEGLKGEQGAPG 663
             G  G  GD G+ GR G  G +GP+G++G+ GP GPPG     G   +++G  G++G  G
Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728

Query: 664  PRGHQGAPGPPGARGPIGPEGRDGP------PGLQGLRGKKGDMGPPGIPGLLGLQGPPG 717
            PRG +G PG PGA G  G EG  GP      PG++G  G+KGD GPPG+ G  GL G PG
Sbjct: 1729 PRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPG 1788

Query: 718  PPGVPGP---------PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKD------GPNGPPG 762
              G  GP         PG  G PGL GE G PG  GPPG  G PG+D      G NG PG
Sbjct: 1789 AAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPG 1848

Query: 763  PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA--------PGFPGV 814
             PG  G  GE+G+ G  G+ G  G  GE+G  G  G +G  GLPG         PG PG 
Sbjct: 1849 DPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG 1908

Query: 815  RGEKGDQGEKGELGLPGLKGDRGEKGEAGPA-------GPPGLPG------------TTS 855
             G KGD+GE G  G  GL G+RG +GE G            G+              ++ 
Sbjct: 1909 TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSG 1968

Query: 856  LFTPHPRM-------PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 908
             F P P          GEQGP G++G  G PGE GL+G  G+ GPQGP G   A G+ G 
Sbjct: 1969 SFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGL--ALGERGP 2026

Query: 909  HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP 968
             G  G AG PG PG  G PG +G  G  G PG RG  G+ GERGE+G  G  G PG  GP
Sbjct: 2027 PGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGP 2086

Query: 969  RGDPG---APGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025
             G PG   +   PGP   G+ G PGL+G+ G PG  G +   G          G   +KG
Sbjct: 2087 PGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGD--------RGVPGIKG 2138

Query: 1026 DRGAP------GIPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075
            DRG P      G PG PG RG  G     G+ GP GP GP G  G PG  G PG  GP G
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198

Query: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL------PGLPG 1129
            P G  G  G PGE GPPG+ GL+     G + L         PPGP GL      PGLPG
Sbjct: 2199 PQGPSGLKGEPGETGPPGR-GLTG--PTGAVGLPG-------PPGPSGLVGPQGSPGLPG 2248

Query: 1130 FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ-------- 1181
              G+ G PG PGR+G  GK G+ G PG+PG PG+ GP G +GE G  G  GQ        
Sbjct: 2249 QVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGA 2308

Query: 1182 KGDQGHP--------GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233
            KG++G P        G PG  G  G PGP G  G AG AG PG  G  G++G PGP+G  
Sbjct: 2309 KGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFK 2368

Query: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
            G PG+    G  G  G PGPPG  G  G PGLPG  G  G PG  G  G+ G PGP GE 
Sbjct: 2369 GDPGV----GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGER 2424

Query: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353
            G  G PG+EG+PG  G  GP G  GP G  G  G  G PG  G PGP G  G+ G +GE+
Sbjct: 2425 GLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGED 2483

Query: 1354 GSPGLPGFLGPRGPPGEPGEKGVPGKE----------------GVPGKPGEPGFKGERGD 1397
            G PG  G  G  GPPG  GE+G  G                  G PG  G  G  GERG 
Sbjct: 2484 GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543

Query: 1398 PGIKGDKGP---------PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
             G+ GDKGP          G KG+PGD G  G  G  GL+GPQG PG  G  G PG PG+
Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGK 2603

Query: 1449 PGFPGLRGESPSMETL-RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK 1507
             G PG+RGE   +  +  R ++ E G +                +   +G  G  GPPG+
Sbjct: 2604 DGVPGIRGEKGDVGFMGPRGLKGERGVK------------GACGLDGEKGDKGEAGPPGR 2651

Query: 1508 DGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQ 1566
             GL G  G MGEPG PGQ G  G  G IGPKG+RG  G PG  G  G +GE G PGI G 
Sbjct: 2652 PGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGF 2711

Query: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP---GPPGQ 1604
            PG  G   DG  G PGP G  GP G  GL G     GPPG+
Sbjct: 2712 PGPSG--NDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGE 2750



 Score =  897 bits (2319), Expect = 0.0
 Identities = 576/1382 (41%), Positives = 675/1382 (48%), Gaps = 303/1382 (21%)

Query: 443  CQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIG 502
            CQ +  T+P P P P                    CP G+KGE G  G  G  GP GD G
Sbjct: 1234 CQASFTTQPRPEPCP------------------VYCPKGQKGEPGEMGLRGQVGPPGDPG 1275

Query: 503  AIGPVGAPGP---------KGEKGDVGI-----------GPFGQGEKGEKGSLGLPGP-- 540
              G  GAPGP         KGE+G  G             P   G  G KGS GLPGP  
Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335

Query: 541  -PGRDGSKGMRGEPGELGE------PGLPGEVGMRGPQGPPGLPGP---PGRVGAPGLQG 590
             PG  G +G +GEPG  G+      PGLPG  G  GP GPPG  GP   PG  G PGL G
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG 1395

Query: 591  E--RGEKGTRGEK------------GERGLDGFPGKPGDTGQ------------------ 618
               +G+KG RGE+            GE GL G PG PG  G                   
Sbjct: 1396 TAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAP 1455

Query: 619  --QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676
               G+PG  G  GP+G  G +GP G  G PG  + + G KGE+G PGP G +G PG  G 
Sbjct: 1456 GLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGP-LGEAGEKGERGPPGPAGSRGLPGVAGR 1514

Query: 677  RGPIGPEGRDGPPGLQ--------------------GLRGKKGDMGPPGIPGLLGLQGPP 716
             G  GPEG  GP G Q                    G +G+KGD+GP G  G  G+QG  
Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574

Query: 717  GPPG--VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP------PGKDGPNGPPGPPGTKG 768
            GPPG  +PG PGP G PG  G IG  G+ GPPG +GP      PG+ GP GP GP G  G
Sbjct: 1575 GPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 769  EPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828
            E GE+G++G PG PGL G+ GE+GL G PG +G           G +G++GD GE G  G
Sbjct: 1635 EVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV---------GEKGDQGDPGEDGRNG 1685

Query: 829  LPGLKGDRGEKGEAGPAGPPGL-----PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 883
             PG  G +G++GE GP GPPG      PG      P  R  G++GP+G KGDPGLPG PG
Sbjct: 1686 SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDR--GQEGPRGPKGDPGLPGAPG 1743

Query: 884  LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRG 943
             +G  G  GP GP G PG +G  G  G  G  G  G  G  G PG +GP G  GA G  G
Sbjct: 1744 ERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAG 1803

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLG 1002
             PG+D   G  G  GE+G PGP GP G PG PG  G PG  GK+GEPG  G  G  G  G
Sbjct: 1804 DPGRD---GLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKG 1860

Query: 1003 TKAACGKVRGSENCALGGQCVKGDRGAPGI------PGSPGSRGDPGIGVAGPPGPSGPP 1056
               A G+         G    KG+RGAPGI      PG PG  G PG G  G PG +GP 
Sbjct: 1861 DSGASGRE--------GRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPK 1912

Query: 1057 GDKGSPGSRGLPGFPGPQG----------------------------------------- 1075
            GD+G  GS+G  G PG +G                                         
Sbjct: 1913 GDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLP 1972

Query: 1076 -PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134
             P  R G  G+ GE+GPPGK G   +  PG+  L      +   PGP G PGL       
Sbjct: 1973 VPERRRGPKGDSGEQGPPGKEG--PIGFPGERGLKG----DRGDPGPQGPPGLA-----L 2021

Query: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194
            G  G PG  G  G+ G+ G PGLPG  G  G  G  GERG  GE G++G+QG  G PG  
Sbjct: 2022 GERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLP 2081

Query: 1195 GPPGNPGPPG--------ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIP------G 1240
            G PG PGPPG          G++G  GPPG++G+ G+ G  G QGP G  G+P      G
Sbjct: 2082 GTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRG 2141

Query: 1241 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAP---------GPRG 1291
            E G  G+DG PG PGE G AG  G PG +G RGPPG  G  GD G P         GP+G
Sbjct: 2142 EPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQG 2201

Query: 1292 ESGAMGLPGQEGLPGKD--------GDTGPTGPQGPQGPRGPP------GKNGSPGSPGE 1337
             SG  G PG+ G PG+         G  GP GP G  GP+G P      G+ G PG+PG 
Sbjct: 2202 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR 2261

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK-----GVPGKEGVPGKP------ 1386
             G SG  G +GS G  GSPGLPG +GP+G PG  G       G+PG +G  G P      
Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321

Query: 1387 --GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
              GEPG KG+RG PG +G+KG  G  G+PGDPG  G KG  G  G +G PG    VG PG
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG----VGVPG 2377

Query: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 1504
             PG PG PG++G              +LG          L  +P A      G PG  GP
Sbjct: 2378 SPGPPGPPGVKG--------------DLG----------LPGLPGA--PGVVGFPGQTGP 2411

Query: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGP------IGPKGERGAKGDPGAPGVGL---R 1555
             G+ G PG +G  G  G PG+ G+ GP GP      +GP G  G KGD G PGVGL   R
Sbjct: 2412 RGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPR 2471

Query: 1556 GEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGPAGHPG-------------LPGPPGP 1601
            GE G PGI G+ G PG     GL G PG +GE G  G  G             + GPPGP
Sbjct: 2472 GERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGP 2531

Query: 1602 PG 1603
             G
Sbjct: 2532 RG 2533



 Score =  885 bits (2288), Expect = 0.0
 Identities = 564/1333 (42%), Positives = 665/1333 (49%), Gaps = 240/1333 (18%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540
            G  G  G+ G  GLPGP+GD G  GP G  G  G  G V IG  G G  G KG    PGP
Sbjct: 1317 GTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV-IGGEGPGLPGRKGD---PGP 1372

Query: 541  PGRDGSKGMRGEPGELGEPGLPGEV--------GMRGPQGP------PGLPGPPGRVGAP 586
             G  G +G  G+PG  G PGLPG          G RGP GP      PG PG PG  G+P
Sbjct: 1373 SGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSP 1432

Query: 587  GLQGERGEKGTRGEKG--ERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG--- 641
            G QG  G  G +GEKG  E G  G PG+PG  G+QG  GP G  GP+G++G  GP G   
Sbjct: 1433 GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAG 1492

Query: 642  ------PPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGL---- 691
                  PPG  GS     GL G  G PG +G +G PGP G +G  G  GR G P +    
Sbjct: 1493 EKGERGPPGPAGS----RGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA 1548

Query: 692  -QGLRGKKGDMGPPGIPGLLGLQGPPGPPGV--PGPPGPGGSPGLPGEIGFPGKPGPPGP 748
              G +G+KGD+GP G  G  G+QG  GPPG+  PG PGP G PG  G IG  G+ GPPG 
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 749  TGPPGKDGPNGPPGPPGT------KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 802
            +GPPG+ G  G PGPPG        GE GE+G++G PG PGL G+ GE+GL G PG +G 
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668

Query: 803  AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGL-----PGTTSLF 857
             G          +G++GD GE G  G PG  G +G++GE GP GPPG      PG     
Sbjct: 1669 VG---------EKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKG 1719

Query: 858  TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 917
             P  R  G++GP+G KGDPGLPG PG +G  G  GP GP G PG +G  G  G  G  G 
Sbjct: 1720 EPGDR--GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL 1777

Query: 918  PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL 977
             G  G  G PG +GP G  GA G  G PG+DG  G +G   E+G PGP GP G PG PG 
Sbjct: 1778 DGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG---EQGLPGPSGPPGLPGKPGE 1834

Query: 978  PGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI---- 1032
             G PG  GK+GEPG  G  G  G  G   A G+         G    KG+RGAPGI    
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGRE--------GRDGPKGERGAPGILGPQ 1886

Query: 1033 --PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG--------------- 1075
              PG PG  G PG G  G PG +GP GD+G  GS+G  G PG +G               
Sbjct: 1887 GPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLL 1946

Query: 1076 ---------------------------PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINL 1108
                                       P  R G  G+ GE+GPPGK G      PG+  L
Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGF--PGERGL 2004

Query: 1109 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG 1168
                  +   PGP G PGL       G  G PG  G  G+ G+ G PGLPG  G  G  G
Sbjct: 2005 KG----DRGDPGPQGPPGLA-----LGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAG 2055

Query: 1169 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG--------ADGIAGAAGPPGIQGS 1220
              GERG  GE G++G+QG  G PG  G PG PGPPG          G++G  GPPG++G+
Sbjct: 2056 RPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGA 2115

Query: 1221 PGKEGPPGPQGPSGLPGIPG------EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 1274
             G+ G  G QGP G  G+PG      E G  G+DG PG PGE G AG  G PG +G RGP
Sbjct: 2116 KGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGP 2175

Query: 1275 PGFKGHTGDSGAPG---------PRGESGAMGLPGQEGLPGKD--------GDTGPTGPQ 1317
            PG  G  GD G PG         P+G SG  G PG+ G PG+         G  GP GP 
Sbjct: 2176 PGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS 2235

Query: 1318 GPQGPRGPPG------KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371
            G  GP+G PG      + G PG+PG  G SG  G +GS G  GSPGLPG +GP+G PG  
Sbjct: 2236 GLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPT 2295

Query: 1372 GEKG-----VPGKEGVPGKPG--------EPGFKGERGDPGIKGDKGPPGGKGQPGDPGI 1418
            G  G     +PG +G  G PG        EPG KG+RG PG +G+KG  G  G+PGDPG 
Sbjct: 2296 GAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGE 2355

Query: 1419 PGHKGHTGLMGPQG-----LPGENGPVGPPGPPGQPGFPGLRGESPSM-----ETLRRLI 1468
             G KG  G  G +G     +PG  GP GPPG  G  G PGL G +P +     +T  R  
Sbjct: 2356 DGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPG-APGVVGFPGQTGPRGE 2414

Query: 1469 QEELGKQLETRLAYLLAQMPPAY--MKSSQGRPGPPG---PPGKDGL-----------PG 1512
              + G   E  LA      PP    +    G PGPPG   PPG  GL           PG
Sbjct: 2415 MGQPGPSGERGLAG-----PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG 2469

Query: 1513 RAGPMGEPG------RPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-------------- 1552
              G  GEPG      RPGQ G  G +GP G +GERG KGD G+ G+              
Sbjct: 2470 PRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPP 2529

Query: 1553 ---GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609
               G +G+MG  G  G  G+ G   D   G PG +G  G  G  G  G PG  G   P  
Sbjct: 2530 GPRGAKGDMGERGPRGLDGDKGPRGDN--GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG 2587

Query: 1610 CAYFASLAARPGN 1622
                A +   PG+
Sbjct: 2588 QPGAAGIPGDPGS 2600



 Score =  877 bits (2266), Expect = 0.0
 Identities = 575/1347 (42%), Positives = 666/1347 (49%), Gaps = 242/1347 (17%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPA--GEKGEMGVAGPMGLPGPKGDIGAIGPV 507
            E  P  P   P  PG       + I    P   G KG+ G +GP G  GP GD G  GP 
Sbjct: 1339 ERGPRGPKGEPGAPG-------QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPP 1391

Query: 508  GAPGP--KGEKGDVGI-GPFGQGEKG-EKGSLGLPGPPGRDGSKGMRGEPGELGE----- 558
            G PG   KG+KGD G  GP G GE G   G  GLPG PG  G +G  G PG+ GE     
Sbjct: 1392 GLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSE 1451

Query: 559  ------PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTR---GEKGERGLDGF 609
                  PG PG  G +GP+GPPG  GP G  G PG  GE GEKG R   G  G RGL G 
Sbjct: 1452 DGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGV 1511

Query: 610  PGKPGDTGQQGRPGPSG--------------------VAGPQGEKGDVGPAGPPGVPGSV 649
             G+PG  G +G PGP+G                    VAGP+GEKGDVGPAGP G     
Sbjct: 1512 AGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGA---- 1567

Query: 650  VQQEGLKGEQGAPG--PRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIP 707
                G++GE+G PG    G  G  G PG RGPIG  GR GPPG  G  G+KGD G PG P
Sbjct: 1568 ---TGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP 1624

Query: 708  GLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP---------PGKDGPN 758
            G +G +G  G  G  G  GP G PGLPG+ G  G  G PG  GP         PG+DG N
Sbjct: 1625 GPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRN 1684

Query: 759  GPPGPPGTKGEPGERGEDGLPGK-----PGLR--GEIGEQGLAGRPGEKGEAGLPGAPGF 811
            G PG  G KG+ GE G  G PG+     PG R  GE G++G  G  G KG+ GLPGAPG 
Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGE 1744

Query: 812  PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
             G+ G +G  G +G+   PG++G  GEKG+    GPPGL G + L    P   G  GP G
Sbjct: 1745 RGIEGFRGPPGPQGD---PGVRGPAGEKGD---RGPPGLDGRSGL-DGKPGAAGPSGPNG 1797

Query: 872  EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG 931
              G  G PG  GL G  GE G  GP+GPPG  G+ G  G PG  G  G PG  G  G  G
Sbjct: 1798 AAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857

Query: 932  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA--PGLPGPPG-KGKDGE 988
              G  GA G  G  G  GERG  G  G +G PG  GP G PG   PG+PG  G KG  GE
Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGE 1917

Query: 989  PGLRGSPGLPGPLGTKAACGKV----RGSENCALGGQCV--------------------- 1023
             G +G  GLPG  G +   G V    R  E   +    +                     
Sbjct: 1918 TGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERR 1977

Query: 1024 ---KGDRGAPGIPGS------------PGSRGDPG--------IGVAGPPGPSGPPGDKG 1060
               KGD G  G PG              G RGDPG        +G  GPPGPSG  G+ G
Sbjct: 1978 RGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPG 2037

Query: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGER---------GPPGKPGLSSLLSPGDINLLAK 1111
             PG  GLPG  G  G AGR G  G  GE+         GPPG PG     +PG       
Sbjct: 2038 KPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPG-----TPG------- 2085

Query: 1112 DVCNDCPPGPPGL--------PGLPGFKGD---KGVPGKPGREGTEGKKGEAGPPGLPGP 1160
                  PPGPPG         PGL G +G    KG  G+PG  G +G KG+ G PG+ G 
Sbjct: 2086 ------PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGD 2139

Query: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP------GNPGPPGADGIAGAA-- 1212
             G  GP+G  G  G  GE G  G +G PG+ G  GPP      G+PGPPGA G+AG A  
Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGP 2199

Query: 1213 -GPPGIQGSPGKEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266
             GP G++G PG+ GPP     GP G  GLPG PG  G  G  G PG PG+ G+ G+PG P
Sbjct: 2200 QGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAP 2259

Query: 1267 GPEGA------RGPPGFKGHTGDSGAPGPRGESGAMGLPGQE--GLPGKDGDTGPTGP-- 1316
            G +GA      RG PG  G  G  G  GP+GE G  G PGQ   GLPG  G+ G  G   
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA 2319

Query: 1317 ---------------QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361
                            GP+G +G  G+ G PG PGE G  G PG KG KG+ G  G+PG 
Sbjct: 2320 GDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGS 2378

Query: 1362 LGPRGPPGEPGEKGVPGKEGVPGK---PGEPGFKGERGDPGIKGDK---GPPGGKGQPGD 1415
             GP GPPG  G+ G+PG  G PG    PG+ G +GE G PG  G++   GPPG +G PG 
Sbjct: 2379 PGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGP 2438

Query: 1416 PGIPGHKGHTGLMGPQGLPGENGP--VGPPGPPGQPGFPGLRGES--PSMETLRRLI--- 1468
             G PG  G  G  G  GL G+ G   VG PGP G+ G PG+RGE   P  E  R L    
Sbjct: 2439 LGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPP 2498

Query: 1469 --QEELGKQLETRLAYLLAQMPPAYMKSSQGRP----GPPGPPGKDGLPGRAGPMGEPGR 1522
              + E G++           +  A +K  +G      GPPGP G  G  G  GP G  G 
Sbjct: 2499 GSRGERGEK---------GDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGD 2549

Query: 1523 PGQGGLEGPSGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYAKDGLP 1578
             G  G  G  G  G KGE G KG  G PG    +G +G+ G  GIPG PG PG  KDG+P
Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPG--KDGVP 2607

Query: 1579 GIPGPQGETGPAGHPGLPGPPGPPGQC 1605
            GI G +G+ G  G  GL G  G  G C
Sbjct: 2608 GIRGEKGDVGFMGPRGLKGERGVKGAC 2634



 Score =  777 bits (2007), Expect = 0.0
 Identities = 478/1123 (42%), Positives = 555/1123 (49%), Gaps = 201/1123 (17%)

Query: 450  EPPPPPPPQR--PPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPV 507
            EP PP PP R     PG+ + G         P G KG+ G+ G  G  G +G  G  GP 
Sbjct: 1698 EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQ 1757

Query: 508  GAPG---PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE 564
            G PG   P GEKGD G  P   G  G  G  G  GP G +G+ G  G+PG  G PGL GE
Sbjct: 1758 GDPGVRGPAGEKGDRG-PPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGE 1816

Query: 565  VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE---KGERGLDGFPGKPGDTGQQGR 621
             G+ GP GPPGLPG PG  G PGL G+ GE G  GE   KGE+G  G  G+ G  G +G 
Sbjct: 1817 QGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGE 1876

Query: 622  PGPSGVAGPQGEKGDVGPAGPPG-----VPGSVVQ-----QEGLKGEQGAPGPRGHQGAP 671
             G  G+ GPQG  G  GP GPPG     VPG         + G KGEQG PG RG +G P
Sbjct: 1877 RGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936

Query: 672  G------------------------------------------PPGARGPIGPEGRDGP- 688
            G                                          P G  G  GP G++GP 
Sbjct: 1937 GSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPI 1996

Query: 689  --PGLQGLRGKKGDMGPPGIPGL-LGLQGPPGPPGVPGPPGPGGSPGLPGE---IGFPGK 742
              PG +GL+G +GD GP G PGL LG +GPPGP G+ G PG  G PGLPG    +G  G+
Sbjct: 1997 GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGR 2056

Query: 743  PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 802
            PG  G  G  G+ G  G  GPPG  G PG       PG PG +  + E G    PG  GE
Sbjct: 2057 PGERGERGEKGERGEQGRDGPPGLPGTPGP------PGPPGPKVSVDEPG----PGLSGE 2106

Query: 803  AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 862
             G PG  G  G  G  GDQG KG+ G+PG+KGDRGE G  G  G PGLPG   +  P  +
Sbjct: 2107 QGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGK 2166

Query: 863  MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG--------A 914
             PG QGP+G  G  G  G+PG  G PG  GP GP GP G KG+ G  G PG        A
Sbjct: 2167 -PGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGA 2225

Query: 915  AGNPGAPGHVGAPGPSGPPG---------SVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965
             G PG PG  G  GP G PG           GAPG  G  GKDG+RG  G  G  G PGP
Sbjct: 2226 VGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP 2285

Query: 966  VGPRGDPGAPGLPG------PPGKGKDG-----------EPGLRGSPGLPGPLGTKAACG 1008
            VGP+G+PG  G PG      P  KG+ G           EPG +G  GLPGP G K   G
Sbjct: 2286 VGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS------P 1062
            +         G     G+ G  G PG  G +GDPG+GV G PGP GPPG KG       P
Sbjct: 2346 RA--------GEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLP 2397

Query: 1063 GSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP 1122
            G+ G+ GFPG  GP G  G PG  GERG  G PG   +  PG +           PPGPP
Sbjct: 2398 GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGI--PGPLG----------PPGPP 2445

Query: 1123 GL---PGLPGFKGDKG-----VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
            G    PG  G KGDKG     +PG  G  G  G +GE G PG  GP G+ GP GS+GERG
Sbjct: 2446 GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG 2505

Query: 1175 ADGEVGQ---KGDQGH-------PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224
              G+VG    KGD+G        PG  G  G  G  GP G DG  G  G  G  G  G +
Sbjct: 2506 EKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSK 2565

Query: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF------- 1277
            G PG +G +GLPG+ G  G +G+ G  G PG+PG  G+ G+PG  G +G  GF       
Sbjct: 2566 GEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625

Query: 1278 --------------KGHTGDSGAPGP------RGESGAMGLPGQEGLPGK---------- 1307
                          KG  G++G PG       +GE G  G+PGQ G PGK          
Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDR 2685

Query: 1308 --DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 1365
              DG  GP G QG +G RG PG  G PG  G  G +G PG  GS G  G  GL G  G R
Sbjct: 2686 GFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGER 2745

Query: 1366 GPPGE-----PGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD 1403
            GPPGE     PG  G PG+ G  G+PG  G +GE+G+  +  D
Sbjct: 2746 GPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  622 bits (1604), Expect = e-178
 Identities = 422/1005 (41%), Positives = 483/1005 (48%), Gaps = 211/1005 (20%)

Query: 791  QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGL 850
            +G  G PGE G  G  G PG PG+ G  G  G +G  G    KG+RG  G  G  G PG 
Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR 1312

Query: 851  PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHG 910
             G           PG  G  G KG PGLPG    +G PGE GP+GP G PGA GQ     
Sbjct: 1313 AGN----------PGTPGAPGLKGSPGLPGP---RGDPGERGPRGPKGEPGAPGQVIGGE 1359

Query: 911  APGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE--RGEKGAAGEEGSPGP--- 965
             PG  G  G PG  G PGP GP   +G PG RG PG  G   +G+KG  GE G PGP   
Sbjct: 1360 GPGLPGRKGDPGPSGPPGPRGP---LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEG 1416

Query: 966  -VGPRGDPGAPGLPG---------PPGK------GKDGEPGLRGSPGLPGPLGTKAACGK 1009
             + P G+PG PGLPG         PPGK       +DG PGL G PG PG  G +   G 
Sbjct: 1417 GIAP-GEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGA 1475

Query: 1010 V-----RGSENCALGGQCVKGDRGAPGIPGS---PGSRGDPGI-GVAGPPGPSGPPGDKG 1060
            +     RG     LG    KG+RG PG  GS   PG  G PG  G  GPPGP+G  G+KG
Sbjct: 1476 IGPKGDRGFPG-PLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKG 1534

Query: 1061 SPGSRGLPGFPGPQ-----------GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLL 1109
             PG  G P   GP            GPAG  GA G  GERGPPG      L+ PGD    
Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPG------LVLPGDPG-- 1586

Query: 1110 AKDVCNDCPP-------GPPGLPGLPGFKGDKGVPGKPG------REGTEGKKGEAGPPG 1156
             K    D  P       GPPG  G PG KGD G PG PG      R+G  G+KG+ GPPG
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646

Query: 1157 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 1216
             PG PG AG +G +G  G  G VG+KGDQG PG  G  G PG+ GP G  G  G  GPPG
Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG 1706

Query: 1217 I-------------QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG---KA 1260
                           G  G+EGP GP+G  GLPG PGE G EG  G PGP G+PG    A
Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320
            GE G  GP G  G  G  G  G +G  GP G +G  G PG++GLPG  G+ G  GP GP 
Sbjct: 1767 GEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPP 1826

Query: 1321 GPRGPPGKNGSPG---SPGEPGPSGTPGQKGSKGENGSPG------------LPGFLGPR 1365
            G  G PG++G PG     GEPG  G  G+KG KG++G+ G             PG LGP+
Sbjct: 1827 GLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQ 1886

Query: 1366 GPPGEPGEKGVPGK--EGVPGK------------------PGEPGFKGE----------- 1394
            GPPG PG  G PG+   GVPG                   PGE G +GE           
Sbjct: 1887 GPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLL 1946

Query: 1395 -------------------------------RGDPGIKGDKGPPGGKGQPGDPGIPGHKG 1423
                                           RG  G  G++GPPG +G  G PG  G KG
Sbjct: 1947 ETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKG 2006

Query: 1424 HTGLMGPQGLPG----ENGPVGPPG---PPGQPGFPGLRGESPSM-ETLRRLIQEELGKQ 1475
              G  GPQG PG    E GP GP G    PG+PG PGL G +  + E  R   + E G++
Sbjct: 2007 DRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEK 2066

Query: 1476 LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP---MGEPGRPGQGGLEGPS 1532
             E               +  QGR GPPG PG  G PG  GP   + EPG PG  G +GP 
Sbjct: 2067 GE---------------RGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPG-PGLSGEQGPP 2110

Query: 1533 GPIGPKGE------RGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGY----AKDGLPGIP 1581
            G  G KGE      +G KGD G PG+ G RGE GP G  G PG PG       +G PG+ 
Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170

Query: 1582 GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            GP+G  GP G  G PGPPG PG   P+     + L   PG    P
Sbjct: 2171 GPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP 2215



 Score =  493 bits (1269), Expect = e-139
 Identities = 299/692 (43%), Positives = 360/692 (52%), Gaps = 87/692 (12%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG-------IGPFG-QGEKG 530
            P G+ G  G+ G  G+ GP+G  G  GP G PGP G  GD G        GP G QG  G
Sbjct: 2145 PRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSG 2204

Query: 531  EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQG 590
             KG  G  GPPGR    G+ G  G +G PG PG  G+ GPQG PGLPG  G  G PG  G
Sbjct: 2205 LKGEPGETGPPGR----GLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 591  ERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSG-----VAGPQGEKGDVGPAGPPGV 645
              G  G  G++G  G+ G PG PG  G +G PGP+G     V G  G KG+ G   P G+
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG--APGGL 2318

Query: 646  PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705
             G +V + G KG++G PGPRG +G  G  G  G  G +G+ G PG +G +G  G +G PG
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPG 2377

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGP------PGPTG------PPG 753
             PG      PPGPPGV G  G  G PG PG +GFPG+ GP      PGP+G      PPG
Sbjct: 2378 SPG------PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431

Query: 754  KDG---PNGPPGPPGTKGEPGERGEDGLPGKPGL-----RGEIGEQGLAGRPGEKGEAGL 805
            ++G   P GPPGPPG+ G PG  G  G  G PG+     RGE GE G+ G  G  G+ G 
Sbjct: 2432 REGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGP 2491

Query: 806  PGAPGFPGVRGEKGDQGEKGELGLPGLKGD----------RGEKGEAGPAGPPGLPGTTS 855
             G  G PG RGE+G++G+ G  GL G KGD          RG KG+ G  GP GL G   
Sbjct: 2492 RGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKG 2551

Query: 856  LFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAA 915
                 PR  G+ G  G+KG  G PG+ G  G PG  G  GP G PGA G  G  G+PG  
Sbjct: 2552 -----PR--GDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKD 2604

Query: 916  GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 975
            G PG  G  G  G  GP G  G  G++G  G DGE+G+KG AG  G PG  G +G+ G P
Sbjct: 2605 GVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEP 2664

Query: 976  GLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPG 1034
            G+PG  G  GK+G  G +G  G  G  G K              G Q  KG+RG PGI G
Sbjct: 2665 GVPGQSGAPGKEGLIGPKGDRGFDGQPGPK--------------GDQGEKGERGTPGIGG 2710

Query: 1035 SPGSRGDPG-IGVAGPPG---PSGPPGDKGSPGSRGLPG-----FPGPQGPAGRDGAPGN 1085
             PG  G+ G  G  GPPG   P GP G +G  G RG PG      PG  G  G  G  G 
Sbjct: 2711 FPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGR 2770

Query: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117
            PG  GP G+ G ++L        + +++   C
Sbjct: 2771 PGPAGPRGEKGEAALTEDDIRGFVRQEMSQHC 2802



 Score =  441 bits (1133), Expect = e-123
 Identities = 289/702 (41%), Positives = 332/702 (47%), Gaps = 147/702 (20%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            EP P      P  PG   +           AG +G+ G+ GP G PGP G  G  GP GA
Sbjct: 2142 EPGPRGQDGNPGLPGERGM-----------AGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190

Query: 510  PG---------PKGEKGDVG-IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPG----- 554
            PG         P G KG+ G  GP G+G  G  G++GLPGPPG  G  G +G PG     
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 555  -------------------ELGEPGLPGEVGMRGPQGPPGLPGPPGR------------- 582
                               + G PG+PG  G+ GP GP G PGP G              
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 583  ------------VGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP 630
                        VG PG +G+RG  G RGEKGE G  G PG PG+ GQ+G PGP G  G 
Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 631  QGE--KGDVGPAGPPGVPGSVVQQEGLKGEQGAPG---------PRGHQGAPGPPGARGP 679
             G    G  GP GPPGV G +    GL G  GAPG         PRG  G PGP G RG 
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDL----GLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGL 2426

Query: 680  IGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGF 739
             GP GR+G PG  G  G  G +GPPG  GL G +G PG  G+PGP G  G PG+ GE G 
Sbjct: 2427 AGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGR 2485

Query: 740  PGKPGPPGPTGPPGKDGPNG----------------------PPGPPGTKGEPGERGEDG 777
            PG+ GP G TGPPG  G  G                      PPGP G KG+ GERG  G
Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG 2545

Query: 778  LPGKPGLRGEIGE---QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG--- 831
            L G  G RG+ G+   +G  G PG+KG AGLPG  G  G +G+ G  G  G+ G PG   
Sbjct: 2546 LDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605

Query: 832  LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891
            + G RGEKG+ G  GP GL G   +        G  G  GEKGD G  G P   GRPG  
Sbjct: 2606 VPGIRGEKGDVGFMGPRGLKGERGV-------KGACGLDGEKGDKGEAGPP---GRPGLA 2655

Query: 892  GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV---GAPGLRGTPGKD 948
            G +G  G PG  GQ GA G  G  G  G  G  G PGP G  G     G PG+ G PG  
Sbjct: 2656 GHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPS 2715

Query: 949  GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK------GKDGEPGLRGSPGLPGPLG 1002
            G  G  G  G  GS GP GP G  G  G  GPPG+      G  G PG RG  G PGP G
Sbjct: 2716 GNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAG 2775

Query: 1003 TKAACGK-------VRG------SENCALGGQCV-KGDRGAP 1030
             +   G+       +RG      S++CA  GQ +  G R  P
Sbjct: 2776 PRGEKGEAALTEDDIRGFVRQEMSQHCACQGQFIASGSRPLP 2817



 Score =  344 bits (882), Expect = 5e-94
 Identities = 227/597 (38%), Positives = 272/597 (45%), Gaps = 153/597 (25%)

Query: 1158 PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP--------------- 1202
            P P  +  P+G +GE G  G  GQ G  G PG+PG  G PG  GP               
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA 1303

Query: 1203 ---------------PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL---------PGI 1238
                           PGA G+ G+ G PG +G PG+ GP GP+G  G          PG+
Sbjct: 1304 DGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGL 1363

Query: 1239 PGEEGKEGRDGKPGP-----------------------------------------PGEP 1257
            PG +G  G  G PGP                                         PGEP
Sbjct: 1364 PGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEP 1423

Query: 1258 GKAGEPGLPGPEGARGPPGFKGHTGDS--GAP------------GPRGESGAMGLPGQEG 1303
            G  G PG PGP+G  GPPG KG  GDS  GAP            GPRG  GA+G  G  G
Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRG 1483

Query: 1304 LP---GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 1360
             P   G+ G+ G  GP GP G RG PG  G PG+ G  GP G  G++G KGE G PG P 
Sbjct: 1484 FPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPA 1543

Query: 1361 FLGPR-----------GPPGEPGEKGVPGKEGVPG--KPGEPGFKGERGDP---GIKGDK 1404
             +GP            GP G  G  GV G+ G PG   PG+PG KG+ GD    G+ G  
Sbjct: 1544 VVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRA 1603

Query: 1405 GPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES--PSME 1462
            GPPG  G PG+ G PG  G  G +GP+G  GE G  G  GPPG PG PG  GE       
Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAP 1663

Query: 1463 TLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK--------------- 1507
             +R  + E+ G Q +            +  K  +G PGPPGPPG+               
Sbjct: 1664 GVRGPVGEK-GDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722

Query: 1508 -DGLPGRAGPMGE---PGRPGQGGLEGPSGPIGPKGE------RGAKGDPGAPGV----- 1552
              G  G  GP G+   PG PG+ G+EG  GP GP+G+       G KGD G PG+     
Sbjct: 1723 DRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 1553 -----GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
                 G  G  GP G  G+ G+PG  +DGLPG+ G QG  GP+G PGLPG PG  G+
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPG--RDGLPGLRGEQGLPGPSGPPGLPGKPGEDGK 1837



 Score =  127 bits (320), Expect = 7e-29
 Identities = 78/194 (40%), Positives = 110/194 (56%), Gaps = 7/194 (3%)

Query: 28  QRAGCKSVHY-DLVFLLDTSSSVGKEDFEKVRQWVANLVDTFE--VGPDRTRVGVVRYSD 84
           +R  C  ++  D+VFLLD SSS+G+ +F +VR ++  LV  F         R   V+YSD
Sbjct: 27  ERVTCTRLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSD 86

Query: 85  RPTTAFELGLFGSQEEVKAAARRLAYHGGNTNTGDALRYITARSFSPHAGGRPRDRAYKQ 144
            P T F L   GS  +V  A R L+Y GGNT TG A+ ++    F P    RP      +
Sbjct: 87  DPRTEFGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLA-RP---GVPK 142

Query: 145 VAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEIASEPKSAHVFHVSDFN 204
           V IL+TDG+SQDLV  AA      G+++FAVG+  A  EEL+ +AS+P S   F V+DF+
Sbjct: 143 VCILITDGKSQDLVDTAAQRLKGQGVKLFAVGIKNADPEELKRVASQPTSDFFFFVNDFS 202

Query: 205 AIDKIRGKLRRRLC 218
            +  +   + RR+C
Sbjct: 203 ILRTLLPLVSRRVC 216



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 38/152 (25%), Positives = 62/152 (40%), Gaps = 4/152 (2%)

Query: 70   VGPDRTRVGVVRYSDRPTTAFELGLFGSQEEVKAAARRLAY-HGGNTNTGDALRYITARS 128
            +GP   +VG++ YS RP+  F L        +    R + Y      N G A+       
Sbjct: 1086 LGPQAVQVGLLSYSHRPSPLFPLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYM 1145

Query: 129  FSPHAGGRPRDRAYKQVAILLTDGRSQDLVLDAAAAAHRAGIRIFAVGVGEALKEELEEI 188
             +P A GR +      V +LL D   +  +      A  +G+ +  +G+  A  E+L  +
Sbjct: 1146 LAPDAPGRRQH--VPGVMVLLVDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRL 1203

Query: 189  ASEPKSAHVFH-VSDFNAIDKIRGKLRRRLCE 219
            A    S   F  V D  ++D+    L   LC+
Sbjct: 1204 APGMDSVQTFFAVDDGPSLDQAVSGLATALCQ 1235



 Score = 35.8 bits (81), Expect = 0.35
 Identities = 22/62 (35%), Positives = 23/62 (37%), Gaps = 9/62 (14%)

Query: 1570 PGYAKDGLPGIPGPQGETGPAGHPGL---------PGPPGPPGQCDPSQCAYFASLAARP 1620
            P Y   G  G PG  G  G  G PG          PGP GPPG         F     RP
Sbjct: 1248 PVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRP 1307

Query: 1621 GN 1622
            G+
Sbjct: 1308 GS 1309


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  894 bits (2310), Expect = 0.0
 Identities = 552/1255 (43%), Positives = 639/1255 (50%), Gaps = 154/1255 (12%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG---------PKGEKGDVGIGPFG-QGEKG 530
            G+ G  G  GP GLPGP G  G +GP G PG         P+G KG +G    G +GE+G
Sbjct: 171  GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 531  EKGSLGLPGPPG-----------RDGSKGMRGEPGELGEPGLPGEVGM--------RGPQ 571
             KG  G PGPPG           R   KG +G+ G +GEPG PG  G+        +G  
Sbjct: 231  VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS------ 625
            G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+      
Sbjct: 291  GDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTY 350

Query: 626  ---------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQG------ 660
                     G  GP+G +G  GP+GPPGVPGS               GLKG +G      
Sbjct: 351  QEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 661  -----APGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPGI----- 706
                  PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG+     
Sbjct: 411  KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470

Query: 707  -PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGKDGPNGP 760
             PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG  G  G 
Sbjct: 471  EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA 530

Query: 761  PGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
             G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G   + G
Sbjct: 531  QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAG--PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 874
            EKGDQG  G+ G PG  G  G  G  G  P G PGL GT  +    P  PGE GP+GE  
Sbjct: 591  EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAGPRGELS 649

Query: 875  -DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933
                +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G PGP GP 
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGPK 708

Query: 934  GSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-----GDPGAPGLPGPPGK-GKDG 987
            G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G  G+ G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENC-------ALGGQCVKGDRGAPGIPGSPGSRG 1040
            E GL G PGLPG  G +   G  RG              G+C++G RGA G+PG  G +G
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 1041 DPGI-GVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQG---PAGRDGAPGNPGERGPPGK 1094
              G  G  GP G  G PG    G PG  G PG PG QG   P G+ G PGNPG  GPPG+
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 1095 PGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
             G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G KGE G
Sbjct: 888  DGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
              G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G+ G AG
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKGLPGPAG 991

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
            PPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG  G +G
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQG 1051

Query: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333
              G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG  GSPG
Sbjct: 1052 DKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393
             PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG  G KG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1394 ERG----DPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------------- 1432
            E G     PG +G+ G  G KG    PG PG+PG KG  G  GP+G              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1433 ---LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 1489
               +PG+ G  GPPG  G PG PG  G   S     +  +  +G             M P
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 1490 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA 1549
                 + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G +GDPG 
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 1550 -PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
               + L G  GPPG PG+PG  G  + G PG PG  G  GP G PG  G PG PG
Sbjct: 1351 LKIISLPGSPGPPGTPGEPGMQG--EPGPPGPPGNLGPCGPRGKPGKDGKPGTPG 1403



 Score =  848 bits (2191), Expect = 0.0
 Identities = 519/1182 (43%), Positives = 606/1182 (51%), Gaps = 151/1182 (12%)

Query: 524  FGQGEKGEKGSLGLPGPPGRDGSKGMRGE---PGELGEPGLPGEVGMRGPQGPPGLPGPP 580
            F  G KGEKG  G PGPPG  G KG  G    PG  G  G PG  G+ G +G  G+ G P
Sbjct: 40   FCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 581  GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640
            G  G+PGL       GT G  G  GL G PG  G  G+QG PG  G  G  G  G  G  
Sbjct: 100  GFSGSPGL------PGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLK 153

Query: 641  GPPGVPGSVVQQE-GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD---GPPGLQGLRG 696
            G  G P      E   KG+ G PG  G QG PGPPG  GP+GP G     G PG  G RG
Sbjct: 154  GQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213

Query: 697  KKGDMGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPP 746
             KG MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPP
Sbjct: 214  PKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273

Query: 747  GPTGPPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804
            GP+G PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP----H 860
              G PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 861  PRMPGEQGPKGEKGDP-----GLPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGA 911
            P  PG +G KGE+G P     G PG PG  G PG  G  GP GPPG     KG  G HG 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 912  PGAAGNPGAPGHVGAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            PG  G+PG PG  G  G             GPPG  G PGL G  G  G +G  G  G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 961  GSPGPVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSP---GLPGPLGT 1003
            GSPG  G  G PG PG  G PG KG+ GE             PGLRG P   GL G  GT
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G        AL G+  KGD+G PG PGSPGS G    G AGPPG  GP G+ G  G
Sbjct: 574  PGVKGLPGPKGELALSGE--KGDQGPPGDPGSPGSPGP--AGPAGPPG-YGPQGEPGLQG 628

Query: 1064 SRGLPGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116
            ++G+PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D
Sbjct: 629  TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGD 684

Query: 1117 ----CPPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP- 1166
                 P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G  
Sbjct: 685  PGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744

Query: 1167 ----QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222
                 G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG
Sbjct: 745  AVAMPGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPG 801

Query: 1223 KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPP 1275
            ++GPP     GP+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G P
Sbjct: 802  EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 1335
            G +G  G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG P
Sbjct: 862  GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP 921

Query: 1336 GEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392
            G  G  GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG K
Sbjct: 922  GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK 981

Query: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP---GENGPVGPPGPPGQP 1449
            G +G PG  G  GP G  G  G+PG PG +G  G MG  G+P   G+ G +G PG  G+P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509
            G PG+ G           +Q + G+              P Y + +  RPGPPGP G  G
Sbjct: 1042 GLPGIHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPG 1074

Query: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPG 1562
            LPG  G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            I G PG PG+     PG PGP G  G  G  G+PGP G  G+
Sbjct: 1135 IRGPPGLPGF-----PGSPGPMGIRGDQGRDGIPGPAGEKGE 1171



 Score =  834 bits (2154), Expect = 0.0
 Identities = 524/1235 (42%), Positives = 619/1235 (50%), Gaps = 198/1235 (16%)

Query: 544  DGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE 603
            DG+KG +GE G  G PG PG+ G  GP+G PG  GP G  G PGL G +G +G  G  G 
Sbjct: 42   DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 604  RGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660
             G  G PG PG+TG  G    PG SG  G QG  G  G  G PG+PG+     GLKG++G
Sbjct: 102  SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA----GLKGQKG 157

Query: 661  AP-----------------GPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRGKKGD 700
            AP                 G  G QG PGPPG  GP+GP G  G    PG  G RG KG 
Sbjct: 158  APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 701  MGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
            MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPPGP+G
Sbjct: 218  MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 751  PPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808
             PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G  G 
Sbjct: 278  LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH----PRMP 864
            PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     P  P
Sbjct: 338  PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 865  GEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGAPGAA 915
            G +G KGE+G PG      PG PG  G PG  G  GP GPPG     KG  G HG PG  
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 916  GNPGAPGHVGAPGPSG-----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
            G+PG PG  G  G  G           PPG  G PGL G  G  G +G  G  G  GSPG
Sbjct: 458  GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 965  PVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSPG---LPGPLGTKAAC 1007
              G  G PG PG  G PG KG+ GE             PGLRG PG   L G  GT    
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 1008 GKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067
            G        AL G+  KGD+G PG PGSPGS G  G   AGPPG  GP G+ G  G++G+
Sbjct: 578  GLPGPKGELALSGE--KGDQGPPGDPGSPGSPGPAG--PAGPPG-YGPQGEPGLQGTQGV 632

Query: 1068 PGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC--- 1117
            PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D    
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGDPGLP 688

Query: 1118 -PPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ---- 1167
             P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G      
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 1168 -GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
             G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG++GP
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1227 PG-----PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPPGFKG 1279
            PG     P+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G PG +G
Sbjct: 806  PGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQG 865

Query: 1280 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
              G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG PG  G
Sbjct: 866  EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG 925

Query: 1340 PSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
              GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG KG +G
Sbjct: 926  QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG 985

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG---ENGPVGPPGPPGQPGFPG 1453
             PG  G  GP G  G  G+PG PG +G  G MG  G+PG   + G +G PG  G+PG PG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513
            + G           +Q + G+              P Y + +  RPGPPGP G  GLPG 
Sbjct: 1046 IHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPGLPGD 1078

Query: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQ 1566
             G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPGI G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1567 PGEPGY-------------AKDGLPGIPGPQGETG----------------------PAG 1591
            PG PG+              +DG+PG  G +GETG                        G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1592 HPGLPG---PPGPPGQCDPSQCAYFASLAARPGNV 1623
             PGLPG     G  G   P+    F      PG +
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233



 Score =  792 bits (2045), Expect = 0.0
 Identities = 483/1090 (44%), Positives = 557/1090 (51%), Gaps = 123/1090 (11%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP--MGLPGPKGDIGAIGPVGAP 510
            P  PP  P +PGS + G           G KGE G  G   MG PG  G  G+ G  G+P
Sbjct: 373  PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432

Query: 511  GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKG-----------------MRGEP 553
            GP G  GD+       G+ G  G LG PG PG DG KG                 + G P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE----RGLDGF 609
            G  G  G+PG  G  G +G PG PG  G  G PG  G +G+ G +GEKGE     G  G 
Sbjct: 493  GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 610  PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG 669
            PG PG  GQ GR G  G+ G  G KG  GP G   + G        KG+QG PG  G  G
Sbjct: 553  PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE-------KGDQGPPGDPGSPG 605

Query: 670  APGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG-------LQGPPGPPGVP 722
            +PGP G  GP G  G  G PGLQG +G  G  GPPG  G  G       + GPPGPPG P
Sbjct: 606  SPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPN--GPPGPPGTKGEPGERGEDGLPG 780
            G PGP G PG+PG +G  G PG PGP G PG  G    GPPGP G +G PG +G  G PG
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 781  KPGLRGEIGEQGLAGRPGEKGEA--GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
            K G  G  G+ GL G  GE   A  G PG PGFPG RG  G+ GE G  GLPGL G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP-----KGEKGDPGLPGEPGLQGRPGELGP 893
            +G  GP G PG PG           PGEQGP     +G +G  GLPG  GL+G+ G  G 
Sbjct: 785  EGLDGPRGDPGQPGP----------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953
             GP G PG  G + + G PG  G+PG PGH G  GP G  G  G PG+ G PG+DG  G 
Sbjct: 835  TGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM 893

Query: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPG---LPGPLGTKAACG- 1008
             G  G  G PGP G  G PG  G PG PG KG+ G PG +G  G    PGP       G 
Sbjct: 894  MGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGD 953

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP 1068
            K         G    KG+RG PG+PG  G +G PG   AGPPGP G  G  G+PG  GL 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 1069 GFPGPQGPAGRDGAPGN------PGERGPPGKPGLSSLLS----PGDINLLAKDVCNDCP 1118
            G PG  G  G  G+ G       PG  G PG PG+  L      PG       +     P
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG-----YSEGTRPGP 1066

Query: 1119 PGPPGLPGLPGF---KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175
            PGP G PGLPG    KG+ G PG PG  G  G +G  G PG PG PG  GP G  G +G 
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126

Query: 1176 DGEVGQKGDQGHPGVPGFMGPPGNPG---PPGADGIAGAAG----------PPGIQGSPG 1222
             G +G  G +G PG+PGF G PG  G     G DGI G AG          PPG +G+PG
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP-----EGARGPPGF 1277
             +G  G +G  G PG+PG +G  G  G  GP G  G  G PGLPG       G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337
            +G  G  G PGP G S  +G+ G +G     G  GP GP G  G  GPPG+ G+PG+PG 
Sbjct: 1247 RGSPGAPGPPGPPG-SHVIGIKGDKG---SMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGK------PGEPGF 1391
            PGP G PG +G  G  G  G PGFLG  GPPG  G KG PG  G PG       PG PG 
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451
             G  G+PG++G+ GP            PG  G+ G  GP+G PG++G  G PGP G+ G 
Sbjct: 1363 PGTPGEPGMQGEPGP------------PGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGN 1410

Query: 1452 PGLRGESPSM 1461
             G +GE  S+
Sbjct: 1411 KGSKGEPESL 1420



 Score =  602 bits (1553), Expect = e-172
 Identities = 371/857 (43%), Positives = 438/857 (51%), Gaps = 127/857 (14%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
            P G   V+    P PP PP  P  PG +            P G  G +G  G  GLPGP 
Sbjct: 644  PRGELSVSTPV-PGPPGPPGPPGHPGPQG-----------PPGIPGSLGKCGDPGLPGPD 691

Query: 499  GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE-----P 553
            G+ G  G +G PGP G KGD G  P  +G  G  G +G PG PG+ G  G +GE     P
Sbjct: 692  GEPGIPG-IGFPGPPGPKGDQGF-PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGK- 612
            G  G PG PGE G  G  G  GLPG PG  G PG +G  G +G  G+ G  G  G PG+ 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 613  -PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671
              G  G QG PG +G+ G QG +G  GP G PG+PG  + + G  GE G+PG  GHQG  
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG--LDRSGFPGETGSPGIPGHQGEM 867

Query: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731
            GP G RG  G  G  GPPG  G+      +G  G PG +   GPPGPPG PG PG  GSP
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGV------IGMMGFPGAI---GPPGPPGNPGTPGQRGSP 918

Query: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPN---------GPPGPPGTKGEPGERGEDGLPGKP 782
            G+PG  G  G PG  G  G  G  GP+         G PG  G  G PGE+G  G+PG P
Sbjct: 919  GIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978

Query: 783  GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842
            GL+G  G  G AG PG +G+ G  G PG PG+RG  G     G +G+PG KG RG  G  
Sbjct: 979  GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM---GNMGMPGSKGKRGTLGFP 1035

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG-----DPGLPGEPGLQGRPGELGPQGPT 897
            G AG PGLPG          + G QG KGE G      PG PG  G  G PG++G +G  
Sbjct: 1036 GRAGRPGLPG----------IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957
            G PG  G  G  G  GA G+PG+P   G PG  GP G +G  G++G  G  G RG  G  
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSP---GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142

Query: 958  GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017
            G  GSPGP+G RGD G  G+PGP   G+ GE GL  +P  PGP G               
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGP--AGEKGETGLLRAP--PGPRGNP------------- 1185

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPG-------IGVAGPPGPSGPP--------GDKGSP 1062
             G Q  KGDRGAPG PG PG +G  G        G+ G PGP G P        G++G P
Sbjct: 1186 -GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244

Query: 1063 GSRGLPGFPGPQGPAGR--------DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            GSRG PG PGP GP G          G+ G+PG +GPPG  G   +  PG +        
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG--DMGPPGRL-------- 1294

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
                 G PG PGLPG +GD G  G PG +G +G  G  G  G PGP G  GP G +G+ G
Sbjct: 1295 -----GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
                +   G  G PG PG  G  G PGPPG  G  G  GP   +G PGK+G PG  GP+ 
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP---RGKPGKDGKPGTPGPA- 1405

Query: 1235 LPGIPGEEGKEGRDGKP 1251
                 GE+G +G  G+P
Sbjct: 1406 -----GEKGNKGSKGEP 1417



 Score =  349 bits (895), Expect = 1e-95
 Identities = 240/647 (37%), Positives = 274/647 (42%), Gaps = 184/647 (28%)

Query: 1133 DKGVPGKPGREGTEGKKGEAGPPGLP------GPPGIAGPQGSQGERGADGEVGQKGDQG 1186
            DKG     G +G +G+KG  GPPG P      GP G+ GPQG +G  G  G  G KG +G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246
              G+PGF G PG PG PG  G  G  G PG  GS G++G PG  G  G PGIPG  G +G
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 1247 RDGK-----------------PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            + G                  PG PG  G  G PG PGP G  GPPGF G  G  G  GP
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 1290 RGESG--AMGLPGQEGLPGKDGDTGP--------TGPQGPQGPRGPPGKNGSPGSPGEPG 1339
            +G  G   +G  G+ G+ G  G  GP        TGP      +G  G  G+ G PG PG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 1340 PSGTPGQK--GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397
            PSG PG+     KG  G PGL G  G  G PG PG +GV G  G PG  GE G KG++GD
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 1398 ---------------------------PGIKGDKGPPGGKGQPGDPGIPGHK-------- 1422
                                       PG +G +GP G  G PG PG PG          
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 1423 -----------------------GHTGLMGPQGLPGENGPVGPP-------GPPGQPGFP 1452
                                   G  G  G  GLPG  GP GPP       GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512
            G  G SP +  +        G + E  L  L  Q P  Y+    G PG PG  G  G+PG
Sbjct: 455  GYLG-SPGIPGVD-------GPKGEPGL--LCTQCP--YIPGPPGLPGLPGLHGVKGIPG 502

Query: 1513 R---AGPMGEPGRPGQGGLEG----------------------PSGPIGPKGERGAKGD- 1546
            R   AG  G PG PG  GL G                      P G +G  G+ G +G  
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 1547 --------PGAPGV-------------GLRGEMGPPGIPGQPGEPGYA------------ 1573
                    PG PGV             G +G+ GPPG PG PG PG A            
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 1574 ------KDGLPGIPGPQGETGPAGH-------PGLPGPPGPPGQCDP 1607
                    G+PG PGP GE GP G        PG PGPPGPPG   P
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669



 Score =  307 bits (786), Expect = 6e-83
 Identities = 210/538 (39%), Positives = 243/538 (45%), Gaps = 114/538 (21%)

Query: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205
            +G KGE G  G PGPPG      S G++G  G  G  G QG  G PG       PG  G+
Sbjct: 42   DGAKGEKGEKGFPGPPG------SPGQKGFTGPEGLPGPQGPKGFPGL------PGLTGS 89

Query: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             G+ G +G PG  GSPG  G PG  GP GL G+P   G  G  G+ G PG PG  G PG+
Sbjct: 90   KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVP---GCSGSKGEQGFPGLPGTLGYPGI 146

Query: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325
            PG  G +G  G      D        E  A G PG  G PG  G  GP G  GP GP GP
Sbjct: 147  PGAAGLKGQKGAPAKEEDI-------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP 199

Query: 1326 PGKNGSPGSPGEPGPSGTPGQK--GSKGENGSPGLPGFLGPRGP--------------PG 1369
            PG  G PG+ G  GP G  G++  G KGE G  GL G  GP G                G
Sbjct: 200  PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259

Query: 1370 EPGEKGVPGKEGVPGKPGEPGF-----KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
            E G+KG  G+ G PG  G PG      KG  GDPG++G  G  G  G PG  G+ G++G 
Sbjct: 260  EKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGF 319

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             GLMG  G+ G+ G +GPPG          RG +   +T +                   
Sbjct: 320  PGLMGEDGIKGQKGDIGPPG---------FRGPTEYYDTYQE------------------ 352

Query: 1485 AQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG-----RPGQGGLEGPSGPIGPKG 1539
                    K  +G PGPPGP G  G  G +GP G PG     RPG  G  G  G  G KG
Sbjct: 353  --------KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 1540 ERG-----AKGDPGAPGV----GLRGEMGPPGIPGQ-------PGE---PGY-AKDGLPG 1579
            ERG     A G PG+PG     GL G  GPPG PG        PG+   PGY    G+PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 1580 IPGPQGETG-----------PAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            + GP+GE G           P G PGLPG  G  G       A        PGN   P
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522



 Score =  242 bits (618), Expect = 2e-63
 Identities = 169/425 (39%), Positives = 191/425 (44%), Gaps = 102/425 (24%)

Query: 1271 ARGPPGFKG----HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            A  P   KG      G     G +GE G  G PG  G PG+ G TGP G  GPQGP+G P
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  GS G  G SG PG  GS    G PG PG  GP G  G PG  G  G++G PG P
Sbjct: 82   GLPGLTGSKGVRGISGLPGFSGSP---GLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP 138

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGK-----GQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
            G  G+ G  G  G+KG KG P  +        GDPG+PG  G  GL GP G P   GPVG
Sbjct: 139  GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP---GPVG 195

Query: 1442 PPGPPGQPGFPGLRG-ESPSMETLRRLIQEELGKQLETRLAYLLAQM-PPAYM------- 1492
            PPGPPG  GFPG  G   P      R+I    G + E  +  L     PP  +       
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVI----GHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 1493 ------------KSSQGRPGPPGP-----------------------PGKDGLPGRAGP- 1516
                        K + G PGPPGP                       PGKDG+PG  G  
Sbjct: 252  DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 1517 -----MGEPGRPGQGGLEGPSGPIGPKGERG---------AKGDPGAPGV----GLRGEM 1558
                  G PG  G+ G++G  G IGP G RG          KGD G PG     G RG  
Sbjct: 312  GVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQ 371

Query: 1559 GPPGIPGQPGEPGYAKDGL------PGIPGPQGETGP--------------AGHPGLPGP 1598
            GP G PG PG PG ++ GL      PG+ G +GE G               AG PGLPG 
Sbjct: 372  GPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431

Query: 1599 PGPPG 1603
            PGPPG
Sbjct: 432  PGPPG 436


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  893 bits (2308), Expect = 0.0
 Identities = 552/1260 (43%), Positives = 639/1260 (50%), Gaps = 157/1260 (12%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG---------PKGEKGDVGIGPFG-QGEKG 530
            G+ G  G  GP GLPGP G  G +GP G PG         P+G KG +G    G +GE+G
Sbjct: 171  GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 531  EKGSLGLPGPPG-----------RDGSKGMRGEPGELGEPGLPGEVGM--------RGPQ 571
             KG  G PGPPG           R   KG +G+ G +GEPG PG  G+        +G  
Sbjct: 231  VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS------ 625
            G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+      
Sbjct: 291  GDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTY 350

Query: 626  ---------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQG------ 660
                     G  GP+G +G  GP+GPPGVPGS               GLKG +G      
Sbjct: 351  QEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 661  -----APGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPGI----- 706
                  PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG+     
Sbjct: 411  KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470

Query: 707  -PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGKDGPNGP 760
             PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG  G  G 
Sbjct: 471  EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA 530

Query: 761  PGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
             G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G   + G
Sbjct: 531  QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAG--PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 874
            EKGDQG  G+ G PG  G  G  G  G  P G PGL GT  +    P  PGE GP+GE  
Sbjct: 591  EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAGPRGELS 649

Query: 875  -DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933
                +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G PGP GP 
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGPK 708

Query: 934  GSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-----GDPGAPGLPGPPGK-GKDG 987
            G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G  G+ G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENC-------ALGGQCVKGDRGAPGIPGSPGSRG 1040
            E GL G PGLPG  G +   G  RG              G+C++G RGA G+PG  G +G
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 1041 DPGI-GVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQG---PAGRDGAPGNPGERGPPGK 1094
              G  G  GP G  G PG    G PG  G PG PG QG   P G+ G PGNPG  GPPG+
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 1095 PGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
             G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G KGE G
Sbjct: 888  DGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
              G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G+ G AG
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKGLPGPAG 991

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
            PPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG  G +G
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQG 1051

Query: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333
              G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG  GSPG
Sbjct: 1052 DKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393
             PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG  G KG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1394 ERG----DPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------------- 1432
            E G     PG +G+ G  G KG    PG PG+PG KG  G  GP+G              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1433 ---LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 1489
               +PG+ G  GPPG  G PG PG  G   S     +  +  +G             M P
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 1490 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA 1549
                 + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G +GDPG 
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 1550 PGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608
              +  L G  GPPG PG+PG       G PG PGP G  GP G  G PG  G PG   P+
Sbjct: 1351 LKIISLPGSPGPPGTPGEPG-----MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405



 Score =  883 bits (2281), Expect = 0.0
 Identities = 563/1321 (42%), Positives = 652/1321 (49%), Gaps = 196/1321 (14%)

Query: 457  PQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPG------------------- 496
            P  P TPG+    G +    CS   GE+G  G+ G +G PG                   
Sbjct: 105  PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 497  ----PKGD---IGAIGPVGAPGPKGEKGDVG-------------IGPFGQ---------G 527
                 KGD    GA GP G PGP G  G VG             +GP G          G
Sbjct: 165  IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224

Query: 528  EKGEKGSLGLPGPPGRDGS--------------KGMRGEPGELGEPGLPGEVGM------ 567
             KGE+G  GL GPPG  G+              KG +G+ G +GEPG PG  G+      
Sbjct: 225  HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284

Query: 568  --RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625
              +G  G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+
Sbjct: 285  SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344

Query: 626  ---------------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQ- 659
                           G  GP+G +G  GP+GPPGVPGS               GLKG + 
Sbjct: 345  EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 660  ----------GAPGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPG 705
                      G PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 706  I------PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGK 754
            +      PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 755  DGPNGPPGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG 810
             G  G  G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA--GPAGPPGLPGTTSLFTPHPRMPGEQG 868
               + GEKGDQG  G+ G PG  G  G  G    GP G PGL GT  +    P  PGE G
Sbjct: 585  ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAG 643

Query: 869  PKGEKG-DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927
            P+GE      +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G P
Sbjct: 644  PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFP 702

Query: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP-----RGDPGAPGLPGPPG 982
            GP GP G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G
Sbjct: 703  GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 983  -KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE-------NCALGGQCVKGDRGAPGIPG 1034
              G+ GE GL G PGLPG  G +   G  RG              G+C++G RGA G+PG
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 1035 SPGSRGDPG-IGVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQ---GPAGRDGAPGNPGE 1088
              G +G  G  G  GP G  G PG    G PG  G PG PG Q   GP G+ G PGNPG 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 1089 RGPPGKPGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 1147
             GPPG+ G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G
Sbjct: 882  LGPPGEDGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 1148 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 1207
             KGE G  G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKG 985

Query: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267
            + G AGPPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327
              G +G  G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG
Sbjct: 1046 IHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387
              GSPG PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1388 EPGFKGE----RGDPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------- 1432
              G KGE    R  PG +G+ G  G KG    PG PG+PG KG  G  GP+G        
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1433 ---------LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYL 1483
                     +PG+ G  GPPG  G PG PG  G   S     +  +  +G          
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1484 LAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543
               M P     + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G 
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1544 KGDPGA-PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPP 1602
            +GDPG    + L G  GPPG PG+PG  G  + G PG PG  G  GP G PG  G PG P
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQG--EPGPPGPPGNLGPCGPRGKPGKDGKPGTP 1402

Query: 1603 G 1603
            G
Sbjct: 1403 G 1403



 Score =  848 bits (2191), Expect = 0.0
 Identities = 519/1182 (43%), Positives = 606/1182 (51%), Gaps = 151/1182 (12%)

Query: 524  FGQGEKGEKGSLGLPGPPGRDGSKGMRGE---PGELGEPGLPGEVGMRGPQGPPGLPGPP 580
            F  G KGEKG  G PGPPG  G KG  G    PG  G  G PG  G+ G +G  G+ G P
Sbjct: 40   FCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 581  GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640
            G  G+PGL       GT G  G  GL G PG  G  G+QG PG  G  G  G  G  G  
Sbjct: 100  GFSGSPGL------PGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLK 153

Query: 641  GPPGVPGSVVQQE-GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD---GPPGLQGLRG 696
            G  G P      E   KG+ G PG  G QG PGPPG  GP+GP G     G PG  G RG
Sbjct: 154  GQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213

Query: 697  KKGDMGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPP 746
             KG MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPP
Sbjct: 214  PKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273

Query: 747  GPTGPPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804
            GP+G PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP----H 860
              G PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 861  PRMPGEQGPKGEKGDP-----GLPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGA 911
            P  PG +G KGE+G P     G PG PG  G PG  G  GP GPPG     KG  G HG 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 912  PGAAGNPGAPGHVGAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            PG  G+PG PG  G  G             GPPG  G PGL G  G  G +G  G  G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 961  GSPGPVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSP---GLPGPLGT 1003
            GSPG  G  G PG PG  G PG KG+ GE             PGLRG P   GL G  GT
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G        AL G+  KGD+G PG PGSPGS G    G AGPPG  GP G+ G  G
Sbjct: 574  PGVKGLPGPKGELALSGE--KGDQGPPGDPGSPGSPGP--AGPAGPPG-YGPQGEPGLQG 628

Query: 1064 SRGLPGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116
            ++G+PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D
Sbjct: 629  TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGD 684

Query: 1117 ----CPPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP- 1166
                 P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G  
Sbjct: 685  PGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744

Query: 1167 ----QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222
                 G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG
Sbjct: 745  AVAMPGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPG 801

Query: 1223 KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPP 1275
            ++GPP     GP+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G P
Sbjct: 802  EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 1335
            G +G  G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG P
Sbjct: 862  GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP 921

Query: 1336 GEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392
            G  G  GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG K
Sbjct: 922  GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK 981

Query: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP---GENGPVGPPGPPGQP 1449
            G +G PG  G  GP G  G  G+PG PG +G  G MG  G+P   G+ G +G PG  G+P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509
            G PG+ G           +Q + G+              P Y + +  RPGPPGP G  G
Sbjct: 1042 GLPGIHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPG 1074

Query: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPG 1562
            LPG  G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            I G PG PG+     PG PGP G  G  G  G+PGP G  G+
Sbjct: 1135 IRGPPGLPGF-----PGSPGPMGIRGDQGRDGIPGPAGEKGE 1171



 Score =  834 bits (2154), Expect = 0.0
 Identities = 524/1235 (42%), Positives = 619/1235 (50%), Gaps = 198/1235 (16%)

Query: 544  DGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE 603
            DG+KG +GE G  G PG PG+ G  GP+G PG  GP G  G PGL G +G +G  G  G 
Sbjct: 42   DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 604  RGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660
             G  G PG PG+TG  G    PG SG  G QG  G  G  G PG+PG+     GLKG++G
Sbjct: 102  SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA----GLKGQKG 157

Query: 661  AP-----------------GPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRGKKGD 700
            AP                 G  G QG PGPPG  GP+GP G  G    PG  G RG KG 
Sbjct: 158  APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 701  MGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
            MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPPGP+G
Sbjct: 218  MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 751  PPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808
             PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G  G 
Sbjct: 278  LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH----PRMP 864
            PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     P  P
Sbjct: 338  PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 865  GEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGAPGAA 915
            G +G KGE+G PG      PG PG  G PG  G  GP GPPG     KG  G HG PG  
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 916  GNPGAPGHVGAPGPSG-----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
            G+PG PG  G  G  G           PPG  G PGL G  G  G +G  G  G  GSPG
Sbjct: 458  GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 965  PVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSPG---LPGPLGTKAAC 1007
              G  G PG PG  G PG KG+ GE             PGLRG PG   L G  GT    
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 1008 GKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067
            G        AL G+  KGD+G PG PGSPGS G  G   AGPPG  GP G+ G  G++G+
Sbjct: 578  GLPGPKGELALSGE--KGDQGPPGDPGSPGSPGPAG--PAGPPG-YGPQGEPGLQGTQGV 632

Query: 1068 PGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC--- 1117
            PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D    
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGDPGLP 688

Query: 1118 -PPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ---- 1167
             P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G      
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 1168 -GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
             G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG++GP
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1227 PG-----PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPPGFKG 1279
            PG     P+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G PG +G
Sbjct: 806  PGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQG 865

Query: 1280 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
              G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG PG  G
Sbjct: 866  EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG 925

Query: 1340 PSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
              GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG KG +G
Sbjct: 926  QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG 985

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG---ENGPVGPPGPPGQPGFPG 1453
             PG  G  GP G  G  G+PG PG +G  G MG  G+PG   + G +G PG  G+PG PG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513
            + G           +Q + G+              P Y + +  RPGPPGP G  GLPG 
Sbjct: 1046 IHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPGLPGD 1078

Query: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQ 1566
             G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPGI G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1567 PGEPGY-------------AKDGLPGIPGPQGETG----------------------PAG 1591
            PG PG+              +DG+PG  G +GETG                        G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1592 HPGLPG---PPGPPGQCDPSQCAYFASLAARPGNV 1623
             PGLPG     G  G   P+    F      PG +
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233



 Score =  801 bits (2070), Expect = 0.0
 Identities = 491/1105 (44%), Positives = 559/1105 (50%), Gaps = 119/1105 (10%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP--MGLPGPKGDIGAIGPVGAP 510
            P  PP  P +PGS + G           G KGE G  G   MG PG  G  G+ G  G+P
Sbjct: 373  PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432

Query: 511  GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKG-----------------MRGEP 553
            GP G  GD+       G+ G  G LG PG PG DG KG                 + G P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE----RGLDGF 609
            G  G  G+PG  G  G +G PG PG  G  G PG  G +G+ G +GEKGE     G  G 
Sbjct: 493  GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 610  PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG 669
            PG PG  GQ GR G  G+ G  G KG  GP G   + G        KG+QG PG  G  G
Sbjct: 553  PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE-------KGDQGPPGDPGSPG 605

Query: 670  APGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG-------LQGPPGPPGVP 722
            +PGP G  GP G  G  G PGLQG +G  G  GPPG  G  G       + GPPGPPG P
Sbjct: 606  SPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPN--GPPGPPGTKGEPGERGEDGLPG 780
            G PGP G PG+PG +G  G PG PGP G PG  G    GPPGP G +G PG +G  G PG
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 781  KPGLRGEIGEQGLAGRPGEKGEA--GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
            K G  G  G+ GL G  GE   A  G PG PGFPG RG  G+ GE G  GLPGL G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP-----KGEKGDPGLPGEPGLQGRPGELGP 893
            +G  GP G PG PG           PGEQGP     +G +G  GLPG  GL+G+ G  G 
Sbjct: 785  EGLDGPRGDPGQPGP----------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953
             GP G PG  G + + G PG  G+PG PGH G  GP G  G  G PG+ G PG+DG  G 
Sbjct: 835  TGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM 893

Query: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPG---LPGPLGTKAACG- 1008
             G  G  G PGP G  G PG  G PG PG KG+ G PG +G  G    PGP       G 
Sbjct: 894  MGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGD 953

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP 1068
            K         G    KG+RG PG+PG  G +G PG   AGPPGP G  G  G+PG  GL 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 1069 GFPGPQGPAGRDGAPGN------PGERGPPGKPGLSSLLS----PGDINLLAKDVCNDCP 1118
            G PG  G  G  G+ G       PG  G PG PG+  L      PG       +     P
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG-----YSEGTRPGP 1066

Query: 1119 PGPPGLPGLPGF---KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175
            PGP G PGLPG    KG+ G PG PG  G  G +G  G PG PG PG  GP G  G +G 
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126

Query: 1176 DGEVGQKGDQGHPGVPGFMGPPGNPG---PPGADGIAGAAG----------PPGIQGSPG 1222
             G +G  G +G PG+PGF G PG  G     G DGI G AG          PPG +G+PG
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP-----EGARGPPGF 1277
             +G  G +G  G PG+PG +G  G  G  GP G  G  G PGLPG       G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337
            +G  G  G PGP G S  +G+ G +G     G  GP GP G  G  GPPG+ G+PG+PG 
Sbjct: 1247 RGSPGAPGPPGPPG-SHVIGIKGDKG---SMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG---------VPGKPGE 1388
            PGP G PG +G  G  G  G PGFLG  GPPG  G KG PG  G         +PG PG 
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 1389 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
            PG  GE G  G  G  GPPG  G  G  G PG  G  G  GP G  G  G  G PGP G 
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS 1422

Query: 1449 PGFPGLRGE-----SPSMETLRRLI 1468
             G PGL+G+     SP+  T R  +
Sbjct: 1423 DGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  621 bits (1602), Expect = e-177
 Identities = 381/879 (43%), Positives = 448/879 (50%), Gaps = 121/879 (13%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
            P G   V+    P PP PP  P  PG +            P G  G +G  G  GLPGP 
Sbjct: 644  PRGELSVSTPV-PGPPGPPGPPGHPGPQG-----------PPGIPGSLGKCGDPGLPGPD 691

Query: 499  GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE-----P 553
            G+ G  G +G PGP G KGD G  P  +G  G  G +G PG PG+ G  G +GE     P
Sbjct: 692  GEPGIPG-IGFPGPPGPKGDQGF-PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGK- 612
            G  G PG PGE G  G  G  GLPG PG  G PG +G  G +G  G+ G  G  G PG+ 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 613  -PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671
              G  G QG PG +G+ G QG +G  GP G PG+PG  + + G  GE G+PG  GHQG  
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG--LDRSGFPGETGSPGIPGHQGEM 867

Query: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731
            GP G RG  G  G  GPPG  G+      +G  G PG +   GPPGPPG PG PG  GSP
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGV------IGMMGFPGAI---GPPGPPGNPGTPGQRGSP 918

Query: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPN---------GPPGPPGTKGEPGERGEDGLPGKP 782
            G+PG  G  G PG  G  G  G  GP+         G PG  G  G PGE+G  G+PG P
Sbjct: 919  GIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978

Query: 783  GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842
            GL+G  G  G AG PG +G+ G  G PG PG+RG  G     G +G+PG KG RG  G  
Sbjct: 979  GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM---GNMGMPGSKGKRGTLGFP 1035

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG-----DPGLPGEPGLQGRPGELGPQGPT 897
            G AG PGLPG          + G QG KGE G      PG PG  G  G PG++G +G  
Sbjct: 1036 GRAGRPGLPG----------IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957
            G PG  G  G  G  GA G+PG+P   G PG  GP G +G  G++G  G  G RG  G  
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSP---GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142

Query: 958  GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017
            G  GSPGP+G RGD G  G+PGP   G+ GE GL  +P  PGP G               
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGP--AGEKGETGLLRAP--PGPRGNP------------- 1185

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPG-------IGVAGPPGPSGPP--------GDKGSP 1062
             G Q  KGDRGAPG PG PG +G  G        G+ G PGP G P        G++G P
Sbjct: 1186 -GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244

Query: 1063 GSRGLPGFPGPQGPAGR--------DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            GSRG PG PGP GP G          G+ G+PG +GPPG  G   +  PG +        
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG--DMGPPGRL-------- 1294

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
                 G PG PGLPG +GD G  G PG +G +G  G  G  G PGP G  GP G +G+ G
Sbjct: 1295 -----GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
                +   G  G PG PG  G  G PGPPG  G  G  GP   +G PGK+G PG  GP+G
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP---RGKPGKDGKPGTPGPAG 1406

Query: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
              G  G +G+ G  G  G PG  GK G+ G P     RG
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  349 bits (895), Expect = 1e-95
 Identities = 240/647 (37%), Positives = 274/647 (42%), Gaps = 184/647 (28%)

Query: 1133 DKGVPGKPGREGTEGKKGEAGPPGLP------GPPGIAGPQGSQGERGADGEVGQKGDQG 1186
            DKG     G +G +G+KG  GPPG P      GP G+ GPQG +G  G  G  G KG +G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246
              G+PGF G PG PG PG  G  G  G PG  GS G++G PG  G  G PGIPG  G +G
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 1247 RDGK-----------------PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            + G                  PG PG  G  G PG PGP G  GPPGF G  G  G  GP
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 1290 RGESG--AMGLPGQEGLPGKDGDTGP--------TGPQGPQGPRGPPGKNGSPGSPGEPG 1339
            +G  G   +G  G+ G+ G  G  GP        TGP      +G  G  G+ G PG PG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 1340 PSGTPGQK--GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397
            PSG PG+     KG  G PGL G  G  G PG PG +GV G  G PG  GE G KG++GD
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 1398 ---------------------------PGIKGDKGPPGGKGQPGDPGIPGHK-------- 1422
                                       PG +G +GP G  G PG PG PG          
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 1423 -----------------------GHTGLMGPQGLPGENGPVGPP-------GPPGQPGFP 1452
                                   G  G  G  GLPG  GP GPP       GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512
            G  G SP +  +        G + E  L  L  Q P  Y+    G PG PG  G  G+PG
Sbjct: 455  GYLG-SPGIPGVD-------GPKGEPGL--LCTQCP--YIPGPPGLPGLPGLHGVKGIPG 502

Query: 1513 R---AGPMGEPGRPGQGGLEG----------------------PSGPIGPKGERGAKGD- 1546
            R   AG  G PG PG  GL G                      P G +G  G+ G +G  
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 1547 --------PGAPGV-------------GLRGEMGPPGIPGQPGEPGYA------------ 1573
                    PG PGV             G +G+ GPPG PG PG PG A            
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 1574 ------KDGLPGIPGPQGETGPAGH-------PGLPGPPGPPGQCDP 1607
                    G+PG PGP GE GP G        PG PGPPGPPG   P
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669



 Score =  312 bits (799), Expect = 2e-84
 Identities = 190/437 (43%), Positives = 218/437 (49%), Gaps = 71/437 (16%)

Query: 449  TEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508
            T P PP P   P  PG                    +MG  G MG PGP G +G  GP G
Sbjct: 1062 TRPGPPGPTGDPGLPG--------------------DMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 509  APGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMR 568
            APG  G  G  G  P   G+ G KG  GL GPPG      +RG PG  G PG PG +G+R
Sbjct: 1102 APGSPGSPGLPG-KPGPHGDLGFKGIKGLLGPPG------IRGPPGLPGFPGSPGPMGIR 1154

Query: 569  GPQGPPGLPGPPGRVGAPGL----QGERGEKGTRGEKGERGLDGFPGKPG---------- 614
            G QG  G+PGP G  G  GL     G RG  G +G KG+RG  GFPG PG          
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 615  --DTGQQGRPGPSGVAG-----------PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661
               TG +G PGP G+ G           P G +G  G  GPPG PGS V   G+KG++G+
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI--GIKGDKGS 1272

Query: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD---MGPPGI------PGLLGL 712
                GH G  GPPG  G +GP GR G PG  GL G +GD    G PG+      PG LG 
Sbjct: 1273 ---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 713  QGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             GPPGP G  GPPG  G PG    I  PG PGPPG  G PG  G  GPPGPPG  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
            RG+ G  GKPG  G  GE+   G  G KGE G  G+ G PG++G++GD G        G 
Sbjct: 1390 RGKPGKDGKPGTPGPAGEK---GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446

Query: 833  KGDRGEKGEAGPAGPPG 849
               R  +  A P+ P G
Sbjct: 1447 VFTRHSQTTAIPSCPEG 1463



 Score =  307 bits (786), Expect = 6e-83
 Identities = 210/538 (39%), Positives = 243/538 (45%), Gaps = 114/538 (21%)

Query: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205
            +G KGE G  G PGPPG      S G++G  G  G  G QG  G PG       PG  G+
Sbjct: 42   DGAKGEKGEKGFPGPPG------SPGQKGFTGPEGLPGPQGPKGFPGL------PGLTGS 89

Query: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             G+ G +G PG  GSPG  G PG  GP GL G+P   G  G  G+ G PG PG  G PG+
Sbjct: 90   KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVP---GCSGSKGEQGFPGLPGTLGYPGI 146

Query: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325
            PG  G +G  G      D        E  A G PG  G PG  G  GP G  GP GP GP
Sbjct: 147  PGAAGLKGQKGAPAKEEDI-------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP 199

Query: 1326 PGKNGSPGSPGEPGPSGTPGQK--GSKGENGSPGLPGFLGPRGP--------------PG 1369
            PG  G PG+ G  GP G  G++  G KGE G  GL G  GP G                G
Sbjct: 200  PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259

Query: 1370 EPGEKGVPGKEGVPGKPGEPGF-----KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
            E G+KG  G+ G PG  G PG      KG  GDPG++G  G  G  G PG  G+ G++G 
Sbjct: 260  EKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGF 319

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             GLMG  G+ G+ G +GPPG          RG +   +T +                   
Sbjct: 320  PGLMGEDGIKGQKGDIGPPG---------FRGPTEYYDTYQE------------------ 352

Query: 1485 AQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG-----RPGQGGLEGPSGPIGPKG 1539
                    K  +G PGPPGP G  G  G +GP G PG     RPG  G  G  G  G KG
Sbjct: 353  --------KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 1540 ERG-----AKGDPGAPGV----GLRGEMGPPGIPGQ-------PGE---PGY-AKDGLPG 1579
            ERG     A G PG+PG     GL G  GPPG PG        PG+   PGY    G+PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 1580 IPGPQGETG-----------PAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            + GP+GE G           P G PGLPG  G  G       A        PGN   P
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522



 Score =  242 bits (618), Expect = 2e-63
 Identities = 169/425 (39%), Positives = 191/425 (44%), Gaps = 102/425 (24%)

Query: 1271 ARGPPGFKG----HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            A  P   KG      G     G +GE G  G PG  G PG+ G TGP G  GPQGP+G P
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  GS G  G SG PG  GS    G PG PG  GP G  G PG  G  G++G PG P
Sbjct: 82   GLPGLTGSKGVRGISGLPGFSGSP---GLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP 138

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGK-----GQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
            G  G+ G  G  G+KG KG P  +        GDPG+PG  G  GL GP G P   GPVG
Sbjct: 139  GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP---GPVG 195

Query: 1442 PPGPPGQPGFPGLRG-ESPSMETLRRLIQEELGKQLETRLAYLLAQM-PPAYM------- 1492
            PPGPPG  GFPG  G   P      R+I    G + E  +  L     PP  +       
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVI----GHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 1493 ------------KSSQGRPGPPGP-----------------------PGKDGLPGRAGP- 1516
                        K + G PGPPGP                       PGKDG+PG  G  
Sbjct: 252  DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 1517 -----MGEPGRPGQGGLEGPSGPIGPKGERG---------AKGDPGAPGV----GLRGEM 1558
                  G PG  G+ G++G  G IGP G RG          KGD G PG     G RG  
Sbjct: 312  GVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQ 371

Query: 1559 GPPGIPGQPGEPGYAKDGL------PGIPGPQGETGP--------------AGHPGLPGP 1598
            GP G PG PG PG ++ GL      PG+ G +GE G               AG PGLPG 
Sbjct: 372  GPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431

Query: 1599 PGPPG 1603
            PGPPG
Sbjct: 432  PGPPG 436


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  893 bits (2308), Expect = 0.0
 Identities = 552/1260 (43%), Positives = 639/1260 (50%), Gaps = 157/1260 (12%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG---------PKGEKGDVGIGPFG-QGEKG 530
            G+ G  G  GP GLPGP G  G +GP G PG         P+G KG +G    G +GE+G
Sbjct: 171  GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 531  EKGSLGLPGPPG-----------RDGSKGMRGEPGELGEPGLPGEVGM--------RGPQ 571
             KG  G PGPPG           R   KG +G+ G +GEPG PG  G+        +G  
Sbjct: 231  VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS------ 625
            G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+      
Sbjct: 291  GDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTY 350

Query: 626  ---------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQG------ 660
                     G  GP+G +G  GP+GPPGVPGS               GLKG +G      
Sbjct: 351  QEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 661  -----APGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPGI----- 706
                  PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG+     
Sbjct: 411  KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470

Query: 707  -PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGKDGPNGP 760
             PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG  G  G 
Sbjct: 471  EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA 530

Query: 761  PGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
             G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G   + G
Sbjct: 531  QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAG--PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 874
            EKGDQG  G+ G PG  G  G  G  G  P G PGL GT  +    P  PGE GP+GE  
Sbjct: 591  EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAGPRGELS 649

Query: 875  -DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933
                +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G PGP GP 
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGPK 708

Query: 934  GSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-----GDPGAPGLPGPPGK-GKDG 987
            G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G  G+ G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENC-------ALGGQCVKGDRGAPGIPGSPGSRG 1040
            E GL G PGLPG  G +   G  RG              G+C++G RGA G+PG  G +G
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 1041 DPGI-GVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQG---PAGRDGAPGNPGERGPPGK 1094
              G  G  GP G  G PG    G PG  G PG PG QG   P G+ G PGNPG  GPPG+
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 1095 PGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
             G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G KGE G
Sbjct: 888  DGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
              G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G+ G AG
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKGLPGPAG 991

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
            PPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG  G +G
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQG 1051

Query: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333
              G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG  GSPG
Sbjct: 1052 DKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393
             PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG  G KG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1394 ERG----DPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------------- 1432
            E G     PG +G+ G  G KG    PG PG+PG KG  G  GP+G              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1433 ---LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 1489
               +PG+ G  GPPG  G PG PG  G   S     +  +  +G             M P
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 1490 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA 1549
                 + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G +GDPG 
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 1550 PGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608
              +  L G  GPPG PG+PG       G PG PGP G  GP G  G PG  G PG   P+
Sbjct: 1351 LKIISLPGSPGPPGTPGEPG-----MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405



 Score =  883 bits (2281), Expect = 0.0
 Identities = 563/1321 (42%), Positives = 652/1321 (49%), Gaps = 196/1321 (14%)

Query: 457  PQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPG------------------- 496
            P  P TPG+    G +    CS   GE+G  G+ G +G PG                   
Sbjct: 105  PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 497  ----PKGD---IGAIGPVGAPGPKGEKGDVG-------------IGPFGQ---------G 527
                 KGD    GA GP G PGP G  G VG             +GP G          G
Sbjct: 165  IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224

Query: 528  EKGEKGSLGLPGPPGRDGS--------------KGMRGEPGELGEPGLPGEVGM------ 567
             KGE+G  GL GPPG  G+              KG +G+ G +GEPG PG  G+      
Sbjct: 225  HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284

Query: 568  --RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625
              +G  G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+
Sbjct: 285  SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344

Query: 626  ---------------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQ- 659
                           G  GP+G +G  GP+GPPGVPGS               GLKG + 
Sbjct: 345  EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 660  ----------GAPGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPG 705
                      G PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 706  I------PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGK 754
            +      PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 755  DGPNGPPGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG 810
             G  G  G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA--GPAGPPGLPGTTSLFTPHPRMPGEQG 868
               + GEKGDQG  G+ G PG  G  G  G    GP G PGL GT  +    P  PGE G
Sbjct: 585  ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAG 643

Query: 869  PKGEKG-DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927
            P+GE      +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G P
Sbjct: 644  PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFP 702

Query: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP-----RGDPGAPGLPGPPG 982
            GP GP G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G
Sbjct: 703  GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 983  -KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE-------NCALGGQCVKGDRGAPGIPG 1034
              G+ GE GL G PGLPG  G +   G  RG              G+C++G RGA G+PG
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 1035 SPGSRGDPG-IGVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQ---GPAGRDGAPGNPGE 1088
              G +G  G  G  GP G  G PG    G PG  G PG PG Q   GP G+ G PGNPG 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 1089 RGPPGKPGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 1147
             GPPG+ G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G
Sbjct: 882  LGPPGEDGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 1148 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 1207
             KGE G  G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKG 985

Query: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267
            + G AGPPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327
              G +G  G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG
Sbjct: 1046 IHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387
              GSPG PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1388 EPGFKGE----RGDPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------- 1432
              G KGE    R  PG +G+ G  G KG    PG PG+PG KG  G  GP+G        
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1433 ---------LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYL 1483
                     +PG+ G  GPPG  G PG PG  G   S     +  +  +G          
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1484 LAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543
               M P     + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G 
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1544 KGDPGA-PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPP 1602
            +GDPG    + L G  GPPG PG+PG  G  + G PG PG  G  GP G PG  G PG P
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQG--EPGPPGPPGNLGPCGPRGKPGKDGKPGTP 1402

Query: 1603 G 1603
            G
Sbjct: 1403 G 1403



 Score =  848 bits (2191), Expect = 0.0
 Identities = 519/1182 (43%), Positives = 606/1182 (51%), Gaps = 151/1182 (12%)

Query: 524  FGQGEKGEKGSLGLPGPPGRDGSKGMRGE---PGELGEPGLPGEVGMRGPQGPPGLPGPP 580
            F  G KGEKG  G PGPPG  G KG  G    PG  G  G PG  G+ G +G  G+ G P
Sbjct: 40   FCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 581  GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640
            G  G+PGL       GT G  G  GL G PG  G  G+QG PG  G  G  G  G  G  
Sbjct: 100  GFSGSPGL------PGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLK 153

Query: 641  GPPGVPGSVVQQE-GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD---GPPGLQGLRG 696
            G  G P      E   KG+ G PG  G QG PGPPG  GP+GP G     G PG  G RG
Sbjct: 154  GQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213

Query: 697  KKGDMGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPP 746
             KG MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPP
Sbjct: 214  PKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273

Query: 747  GPTGPPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804
            GP+G PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP----H 860
              G PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 861  PRMPGEQGPKGEKGDP-----GLPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGA 911
            P  PG +G KGE+G P     G PG PG  G PG  G  GP GPPG     KG  G HG 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 912  PGAAGNPGAPGHVGAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            PG  G+PG PG  G  G             GPPG  G PGL G  G  G +G  G  G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 961  GSPGPVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSP---GLPGPLGT 1003
            GSPG  G  G PG PG  G PG KG+ GE             PGLRG P   GL G  GT
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G        AL G+  KGD+G PG PGSPGS G    G AGPPG  GP G+ G  G
Sbjct: 574  PGVKGLPGPKGELALSGE--KGDQGPPGDPGSPGSPGP--AGPAGPPG-YGPQGEPGLQG 628

Query: 1064 SRGLPGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116
            ++G+PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D
Sbjct: 629  TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGD 684

Query: 1117 ----CPPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP- 1166
                 P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G  
Sbjct: 685  PGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744

Query: 1167 ----QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222
                 G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG
Sbjct: 745  AVAMPGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPG 801

Query: 1223 KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPP 1275
            ++GPP     GP+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G P
Sbjct: 802  EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 1335
            G +G  G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG P
Sbjct: 862  GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP 921

Query: 1336 GEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392
            G  G  GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG K
Sbjct: 922  GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK 981

Query: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP---GENGPVGPPGPPGQP 1449
            G +G PG  G  GP G  G  G+PG PG +G  G MG  G+P   G+ G +G PG  G+P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509
            G PG+ G           +Q + G+              P Y + +  RPGPPGP G  G
Sbjct: 1042 GLPGIHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPG 1074

Query: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPG 1562
            LPG  G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            I G PG PG+     PG PGP G  G  G  G+PGP G  G+
Sbjct: 1135 IRGPPGLPGF-----PGSPGPMGIRGDQGRDGIPGPAGEKGE 1171



 Score =  834 bits (2154), Expect = 0.0
 Identities = 524/1235 (42%), Positives = 619/1235 (50%), Gaps = 198/1235 (16%)

Query: 544  DGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE 603
            DG+KG +GE G  G PG PG+ G  GP+G PG  GP G  G PGL G +G +G  G  G 
Sbjct: 42   DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 604  RGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660
             G  G PG PG+TG  G    PG SG  G QG  G  G  G PG+PG+     GLKG++G
Sbjct: 102  SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA----GLKGQKG 157

Query: 661  AP-----------------GPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRGKKGD 700
            AP                 G  G QG PGPPG  GP+GP G  G    PG  G RG KG 
Sbjct: 158  APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 701  MGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
            MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPPGP+G
Sbjct: 218  MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 751  PPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808
             PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G  G 
Sbjct: 278  LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH----PRMP 864
            PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     P  P
Sbjct: 338  PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 865  GEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGAPGAA 915
            G +G KGE+G PG      PG PG  G PG  G  GP GPPG     KG  G HG PG  
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 916  GNPGAPGHVGAPGPSG-----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
            G+PG PG  G  G  G           PPG  G PGL G  G  G +G  G  G  GSPG
Sbjct: 458  GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 965  PVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSPG---LPGPLGTKAAC 1007
              G  G PG PG  G PG KG+ GE             PGLRG PG   L G  GT    
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 1008 GKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067
            G        AL G+  KGD+G PG PGSPGS G  G   AGPPG  GP G+ G  G++G+
Sbjct: 578  GLPGPKGELALSGE--KGDQGPPGDPGSPGSPGPAG--PAGPPG-YGPQGEPGLQGTQGV 632

Query: 1068 PGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC--- 1117
            PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D    
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGDPGLP 688

Query: 1118 -PPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ---- 1167
             P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G      
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 1168 -GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
             G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG++GP
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1227 PG-----PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPPGFKG 1279
            PG     P+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G PG +G
Sbjct: 806  PGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQG 865

Query: 1280 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
              G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG PG  G
Sbjct: 866  EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG 925

Query: 1340 PSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
              GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG KG +G
Sbjct: 926  QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG 985

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG---ENGPVGPPGPPGQPGFPG 1453
             PG  G  GP G  G  G+PG PG +G  G MG  G+PG   + G +G PG  G+PG PG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513
            + G           +Q + G+              P Y + +  RPGPPGP G  GLPG 
Sbjct: 1046 IHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPGLPGD 1078

Query: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQ 1566
             G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPGI G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1567 PGEPGY-------------AKDGLPGIPGPQGETG----------------------PAG 1591
            PG PG+              +DG+PG  G +GETG                        G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1592 HPGLPG---PPGPPGQCDPSQCAYFASLAARPGNV 1623
             PGLPG     G  G   P+    F      PG +
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233



 Score =  801 bits (2070), Expect = 0.0
 Identities = 491/1105 (44%), Positives = 559/1105 (50%), Gaps = 119/1105 (10%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP--MGLPGPKGDIGAIGPVGAP 510
            P  PP  P +PGS + G           G KGE G  G   MG PG  G  G+ G  G+P
Sbjct: 373  PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432

Query: 511  GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKG-----------------MRGEP 553
            GP G  GD+       G+ G  G LG PG PG DG KG                 + G P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE----RGLDGF 609
            G  G  G+PG  G  G +G PG PG  G  G PG  G +G+ G +GEKGE     G  G 
Sbjct: 493  GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 610  PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG 669
            PG PG  GQ GR G  G+ G  G KG  GP G   + G        KG+QG PG  G  G
Sbjct: 553  PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE-------KGDQGPPGDPGSPG 605

Query: 670  APGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG-------LQGPPGPPGVP 722
            +PGP G  GP G  G  G PGLQG +G  G  GPPG  G  G       + GPPGPPG P
Sbjct: 606  SPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPN--GPPGPPGTKGEPGERGEDGLPG 780
            G PGP G PG+PG +G  G PG PGP G PG  G    GPPGP G +G PG +G  G PG
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 781  KPGLRGEIGEQGLAGRPGEKGEA--GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
            K G  G  G+ GL G  GE   A  G PG PGFPG RG  G+ GE G  GLPGL G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP-----KGEKGDPGLPGEPGLQGRPGELGP 893
            +G  GP G PG PG           PGEQGP     +G +G  GLPG  GL+G+ G  G 
Sbjct: 785  EGLDGPRGDPGQPGP----------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953
             GP G PG  G + + G PG  G+PG PGH G  GP G  G  G PG+ G PG+DG  G 
Sbjct: 835  TGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM 893

Query: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPG---LPGPLGTKAACG- 1008
             G  G  G PGP G  G PG  G PG PG KG+ G PG +G  G    PGP       G 
Sbjct: 894  MGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGD 953

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP 1068
            K         G    KG+RG PG+PG  G +G PG   AGPPGP G  G  G+PG  GL 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 1069 GFPGPQGPAGRDGAPGN------PGERGPPGKPGLSSLLS----PGDINLLAKDVCNDCP 1118
            G PG  G  G  G+ G       PG  G PG PG+  L      PG       +     P
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG-----YSEGTRPGP 1066

Query: 1119 PGPPGLPGLPGF---KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175
            PGP G PGLPG    KG+ G PG PG  G  G +G  G PG PG PG  GP G  G +G 
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126

Query: 1176 DGEVGQKGDQGHPGVPGFMGPPGNPG---PPGADGIAGAAG----------PPGIQGSPG 1222
             G +G  G +G PG+PGF G PG  G     G DGI G AG          PPG +G+PG
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP-----EGARGPPGF 1277
             +G  G +G  G PG+PG +G  G  G  GP G  G  G PGLPG       G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337
            +G  G  G PGP G S  +G+ G +G     G  GP GP G  G  GPPG+ G+PG+PG 
Sbjct: 1247 RGSPGAPGPPGPPG-SHVIGIKGDKG---SMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG---------VPGKPGE 1388
            PGP G PG +G  G  G  G PGFLG  GPPG  G KG PG  G         +PG PG 
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 1389 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
            PG  GE G  G  G  GPPG  G  G  G PG  G  G  GP G  G  G  G PGP G 
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS 1422

Query: 1449 PGFPGLRGE-----SPSMETLRRLI 1468
             G PGL+G+     SP+  T R  +
Sbjct: 1423 DGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  621 bits (1602), Expect = e-177
 Identities = 381/879 (43%), Positives = 448/879 (50%), Gaps = 121/879 (13%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
            P G   V+    P PP PP  P  PG +            P G  G +G  G  GLPGP 
Sbjct: 644  PRGELSVSTPV-PGPPGPPGPPGHPGPQG-----------PPGIPGSLGKCGDPGLPGPD 691

Query: 499  GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE-----P 553
            G+ G  G +G PGP G KGD G  P  +G  G  G +G PG PG+ G  G +GE     P
Sbjct: 692  GEPGIPG-IGFPGPPGPKGDQGF-PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGK- 612
            G  G PG PGE G  G  G  GLPG PG  G PG +G  G +G  G+ G  G  G PG+ 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 613  -PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671
              G  G QG PG +G+ G QG +G  GP G PG+PG  + + G  GE G+PG  GHQG  
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG--LDRSGFPGETGSPGIPGHQGEM 867

Query: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731
            GP G RG  G  G  GPPG  G+      +G  G PG +   GPPGPPG PG PG  GSP
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGV------IGMMGFPGAI---GPPGPPGNPGTPGQRGSP 918

Query: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPN---------GPPGPPGTKGEPGERGEDGLPGKP 782
            G+PG  G  G PG  G  G  G  GP+         G PG  G  G PGE+G  G+PG P
Sbjct: 919  GIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978

Query: 783  GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842
            GL+G  G  G AG PG +G+ G  G PG PG+RG  G     G +G+PG KG RG  G  
Sbjct: 979  GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM---GNMGMPGSKGKRGTLGFP 1035

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG-----DPGLPGEPGLQGRPGELGPQGPT 897
            G AG PGLPG          + G QG KGE G      PG PG  G  G PG++G +G  
Sbjct: 1036 GRAGRPGLPG----------IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957
            G PG  G  G  G  GA G+PG+P   G PG  GP G +G  G++G  G  G RG  G  
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSP---GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142

Query: 958  GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017
            G  GSPGP+G RGD G  G+PGP   G+ GE GL  +P  PGP G               
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGP--AGEKGETGLLRAP--PGPRGNP------------- 1185

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPG-------IGVAGPPGPSGPP--------GDKGSP 1062
             G Q  KGDRGAPG PG PG +G  G        G+ G PGP G P        G++G P
Sbjct: 1186 -GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244

Query: 1063 GSRGLPGFPGPQGPAGR--------DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            GSRG PG PGP GP G          G+ G+PG +GPPG  G   +  PG +        
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG--DMGPPGRL-------- 1294

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
                 G PG PGLPG +GD G  G PG +G +G  G  G  G PGP G  GP G +G+ G
Sbjct: 1295 -----GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
                +   G  G PG PG  G  G PGPPG  G  G  GP   +G PGK+G PG  GP+G
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP---RGKPGKDGKPGTPGPAG 1406

Query: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
              G  G +G+ G  G  G PG  GK G+ G P     RG
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  349 bits (895), Expect = 1e-95
 Identities = 240/647 (37%), Positives = 274/647 (42%), Gaps = 184/647 (28%)

Query: 1133 DKGVPGKPGREGTEGKKGEAGPPGLP------GPPGIAGPQGSQGERGADGEVGQKGDQG 1186
            DKG     G +G +G+KG  GPPG P      GP G+ GPQG +G  G  G  G KG +G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246
              G+PGF G PG PG PG  G  G  G PG  GS G++G PG  G  G PGIPG  G +G
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 1247 RDGK-----------------PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            + G                  PG PG  G  G PG PGP G  GPPGF G  G  G  GP
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 1290 RGESG--AMGLPGQEGLPGKDGDTGP--------TGPQGPQGPRGPPGKNGSPGSPGEPG 1339
            +G  G   +G  G+ G+ G  G  GP        TGP      +G  G  G+ G PG PG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 1340 PSGTPGQK--GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397
            PSG PG+     KG  G PGL G  G  G PG PG +GV G  G PG  GE G KG++GD
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 1398 ---------------------------PGIKGDKGPPGGKGQPGDPGIPGHK-------- 1422
                                       PG +G +GP G  G PG PG PG          
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 1423 -----------------------GHTGLMGPQGLPGENGPVGPP-------GPPGQPGFP 1452
                                   G  G  G  GLPG  GP GPP       GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512
            G  G SP +  +        G + E  L  L  Q P  Y+    G PG PG  G  G+PG
Sbjct: 455  GYLG-SPGIPGVD-------GPKGEPGL--LCTQCP--YIPGPPGLPGLPGLHGVKGIPG 502

Query: 1513 R---AGPMGEPGRPGQGGLEG----------------------PSGPIGPKGERGAKGD- 1546
            R   AG  G PG PG  GL G                      P G +G  G+ G +G  
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 1547 --------PGAPGV-------------GLRGEMGPPGIPGQPGEPGYA------------ 1573
                    PG PGV             G +G+ GPPG PG PG PG A            
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 1574 ------KDGLPGIPGPQGETGPAGH-------PGLPGPPGPPGQCDP 1607
                    G+PG PGP GE GP G        PG PGPPGPPG   P
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669



 Score =  312 bits (799), Expect = 2e-84
 Identities = 190/437 (43%), Positives = 218/437 (49%), Gaps = 71/437 (16%)

Query: 449  TEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508
            T P PP P   P  PG                    +MG  G MG PGP G +G  GP G
Sbjct: 1062 TRPGPPGPTGDPGLPG--------------------DMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 509  APGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMR 568
            APG  G  G  G  P   G+ G KG  GL GPPG      +RG PG  G PG PG +G+R
Sbjct: 1102 APGSPGSPGLPG-KPGPHGDLGFKGIKGLLGPPG------IRGPPGLPGFPGSPGPMGIR 1154

Query: 569  GPQGPPGLPGPPGRVGAPGL----QGERGEKGTRGEKGERGLDGFPGKPG---------- 614
            G QG  G+PGP G  G  GL     G RG  G +G KG+RG  GFPG PG          
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 615  --DTGQQGRPGPSGVAG-----------PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661
               TG +G PGP G+ G           P G +G  G  GPPG PGS V   G+KG++G+
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI--GIKGDKGS 1272

Query: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD---MGPPGI------PGLLGL 712
                GH G  GPPG  G +GP GR G PG  GL G +GD    G PG+      PG LG 
Sbjct: 1273 ---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 713  QGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             GPPGP G  GPPG  G PG    I  PG PGPPG  G PG  G  GPPGPPG  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
            RG+ G  GKPG  G  GE+   G  G KGE G  G+ G PG++G++GD G        G 
Sbjct: 1390 RGKPGKDGKPGTPGPAGEK---GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446

Query: 833  KGDRGEKGEAGPAGPPG 849
               R  +  A P+ P G
Sbjct: 1447 VFTRHSQTTAIPSCPEG 1463



 Score =  307 bits (786), Expect = 6e-83
 Identities = 210/538 (39%), Positives = 243/538 (45%), Gaps = 114/538 (21%)

Query: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205
            +G KGE G  G PGPPG      S G++G  G  G  G QG  G PG       PG  G+
Sbjct: 42   DGAKGEKGEKGFPGPPG------SPGQKGFTGPEGLPGPQGPKGFPGL------PGLTGS 89

Query: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             G+ G +G PG  GSPG  G PG  GP GL G+P   G  G  G+ G PG PG  G PG+
Sbjct: 90   KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVP---GCSGSKGEQGFPGLPGTLGYPGI 146

Query: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325
            PG  G +G  G      D        E  A G PG  G PG  G  GP G  GP GP GP
Sbjct: 147  PGAAGLKGQKGAPAKEEDI-------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP 199

Query: 1326 PGKNGSPGSPGEPGPSGTPGQK--GSKGENGSPGLPGFLGPRGP--------------PG 1369
            PG  G PG+ G  GP G  G++  G KGE G  GL G  GP G                G
Sbjct: 200  PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259

Query: 1370 EPGEKGVPGKEGVPGKPGEPGF-----KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
            E G+KG  G+ G PG  G PG      KG  GDPG++G  G  G  G PG  G+ G++G 
Sbjct: 260  EKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGF 319

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             GLMG  G+ G+ G +GPPG          RG +   +T +                   
Sbjct: 320  PGLMGEDGIKGQKGDIGPPG---------FRGPTEYYDTYQE------------------ 352

Query: 1485 AQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG-----RPGQGGLEGPSGPIGPKG 1539
                    K  +G PGPPGP G  G  G +GP G PG     RPG  G  G  G  G KG
Sbjct: 353  --------KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 1540 ERG-----AKGDPGAPGV----GLRGEMGPPGIPGQ-------PGE---PGY-AKDGLPG 1579
            ERG     A G PG+PG     GL G  GPPG PG        PG+   PGY    G+PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 1580 IPGPQGETG-----------PAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            + GP+GE G           P G PGLPG  G  G       A        PGN   P
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522



 Score =  242 bits (618), Expect = 2e-63
 Identities = 169/425 (39%), Positives = 191/425 (44%), Gaps = 102/425 (24%)

Query: 1271 ARGPPGFKG----HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            A  P   KG      G     G +GE G  G PG  G PG+ G TGP G  GPQGP+G P
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  GS G  G SG PG  GS    G PG PG  GP G  G PG  G  G++G PG P
Sbjct: 82   GLPGLTGSKGVRGISGLPGFSGSP---GLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP 138

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGK-----GQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
            G  G+ G  G  G+KG KG P  +        GDPG+PG  G  GL GP G P   GPVG
Sbjct: 139  GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP---GPVG 195

Query: 1442 PPGPPGQPGFPGLRG-ESPSMETLRRLIQEELGKQLETRLAYLLAQM-PPAYM------- 1492
            PPGPPG  GFPG  G   P      R+I    G + E  +  L     PP  +       
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVI----GHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 1493 ------------KSSQGRPGPPGP-----------------------PGKDGLPGRAGP- 1516
                        K + G PGPPGP                       PGKDG+PG  G  
Sbjct: 252  DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 1517 -----MGEPGRPGQGGLEGPSGPIGPKGERG---------AKGDPGAPGV----GLRGEM 1558
                  G PG  G+ G++G  G IGP G RG          KGD G PG     G RG  
Sbjct: 312  GVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQ 371

Query: 1559 GPPGIPGQPGEPGYAKDGL------PGIPGPQGETGP--------------AGHPGLPGP 1598
            GP G PG PG PG ++ GL      PG+ G +GE G               AG PGLPG 
Sbjct: 372  GPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431

Query: 1599 PGPPG 1603
            PGPPG
Sbjct: 432  PGPPG 436


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  893 bits (2308), Expect = 0.0
 Identities = 552/1260 (43%), Positives = 639/1260 (50%), Gaps = 157/1260 (12%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG---------PKGEKGDVGIGPFG-QGEKG 530
            G+ G  G  GP GLPGP G  G +GP G PG         P+G KG +G    G +GE+G
Sbjct: 171  GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 531  EKGSLGLPGPPG-----------RDGSKGMRGEPGELGEPGLPGEVGM--------RGPQ 571
             KG  G PGPPG           R   KG +G+ G +GEPG PG  G+        +G  
Sbjct: 231  VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS------ 625
            G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+      
Sbjct: 291  GDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTY 350

Query: 626  ---------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQG------ 660
                     G  GP+G +G  GP+GPPGVPGS               GLKG +G      
Sbjct: 351  QEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 661  -----APGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPGI----- 706
                  PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG+     
Sbjct: 411  KDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470

Query: 707  -PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGKDGPNGP 760
             PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG  G  G 
Sbjct: 471  EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGA 530

Query: 761  PGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
             G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G   + G
Sbjct: 531  QGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSG 590

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAG--PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 874
            EKGDQG  G+ G PG  G  G  G  G  P G PGL GT  +    P  PGE GP+GE  
Sbjct: 591  EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAGPRGELS 649

Query: 875  -DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933
                +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G PGP GP 
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFPGPPGPK 708

Query: 934  GSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR-----GDPGAPGLPGPPGK-GKDG 987
            G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G  G+ G
Sbjct: 709  GDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHG 768

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGSENC-------ALGGQCVKGDRGAPGIPGSPGSRG 1040
            E GL G PGLPG  G +   G  RG              G+C++G RGA G+PG  G +G
Sbjct: 769  EIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 1041 DPGI-GVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQG---PAGRDGAPGNPGERGPPGK 1094
              G  G  GP G  G PG    G PG  G PG PG QG   P G+ G PGNPG  GPPG+
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGE 887

Query: 1095 PGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
             G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G KGE G
Sbjct: 888  DGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQG 937

Query: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
              G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G+ G AG
Sbjct: 938  DKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKGLPGPAG 991

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
            PPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG  G +G
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQG 1051

Query: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333
              G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG  GSPG
Sbjct: 1052 DKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393
             PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG  G KG
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 1394 ERG----DPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------------- 1432
            E G     PG +G+ G  G KG    PG PG+PG KG  G  GP+G              
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 1433 ---LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 1489
               +PG+ G  GPPG  G PG PG  G   S     +  +  +G             M P
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGP 1290

Query: 1490 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA 1549
                 + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G +GDPG 
Sbjct: 1291 PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGT 1350

Query: 1550 PGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608
              +  L G  GPPG PG+PG       G PG PGP G  GP G  G PG  G PG   P+
Sbjct: 1351 LKIISLPGSPGPPGTPGEPG-----MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405



 Score =  883 bits (2281), Expect = 0.0
 Identities = 563/1321 (42%), Positives = 652/1321 (49%), Gaps = 196/1321 (14%)

Query: 457  PQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPG------------------- 496
            P  P TPG+    G +    CS   GE+G  G+ G +G PG                   
Sbjct: 105  PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 497  ----PKGD---IGAIGPVGAPGPKGEKGDVG-------------IGPFGQ---------G 527
                 KGD    GA GP G PGP G  G VG             +GP G          G
Sbjct: 165  IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIG 224

Query: 528  EKGEKGSLGLPGPPGRDGS--------------KGMRGEPGELGEPGLPGEVGM------ 567
             KGE+G  GL GPPG  G+              KG +G+ G +GEPG PG  G+      
Sbjct: 225  HKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYG 284

Query: 568  --RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625
              +G  G PGL G PG+ G PG  G  G KG RG  G  G DG  G+ GD G  G  GP+
Sbjct: 285  SEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPT 344

Query: 626  ---------------GVAGPQGEKGDVGPAGPPGVPGSVVQQE----------GLKGEQ- 659
                           G  GP+G +G  GP+GPPGVPGS               GLKG + 
Sbjct: 345  EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 660  ----------GAPGPRGHQGAPGPPGARGPIGPEG----RDGPPGLQGLRGKKGDMGPPG 705
                      G PG  G  G+PG PG+ GP GP G    R GPPG  GL G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 706  I------PGLLGLQGP--PGPPGVPGPPGPGGSPGLPGE---IGFPGKPGPPGPTGPPGK 754
            +      PGLL  Q P  PGPPG+PG PG  G  G+PG     G  G PG PG TG PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 755  DGPNGPPGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG 810
             G  G  G PG KGE GE     G+ G+PG PGLRG+ G +GL G PG  G  GLPG  G
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA--GPAGPPGLPGTTSLFTPHPRMPGEQG 868
               + GEKGDQG  G+ G PG  G  G  G    GP G PGL GT  +    P  PGE G
Sbjct: 585  ELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV-PGAPGPPGEAG 643

Query: 869  PKGEKG-DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP 927
            P+GE      +PG PG  G PG  GPQGP G PG+ G+ G  G PG  G PG PG +G P
Sbjct: 644  PRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG-IGFP 702

Query: 928  GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP-----RGDPGAPGLPGPPG 982
            GP GP G  G PG +G+ G  G+ GE G  G+ G PG  G       G PG PG PG  G
Sbjct: 703  GPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERG 762

Query: 983  -KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE-------NCALGGQCVKGDRGAPGIPG 1034
              G+ GE GL G PGLPG  G +   G  RG              G+C++G RGA G+PG
Sbjct: 763  NSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPG 821

Query: 1035 SPGSRGDPG-IGVAGPPGPSGPPG--DKGSPGSRGLPGFPGPQ---GPAGRDGAPGNPGE 1088
              G +G  G  G  GP G  G PG    G PG  G PG PG Q   GP G+ G PGNPG 
Sbjct: 822  LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881

Query: 1089 RGPPGKPGLSSLLS-PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 1147
             GPPG+ G+  ++  PG I           PPGPPG PG PG +G  G+PG  G+ GT G
Sbjct: 882  LGPPGEDGVIGMMGFPGAIG----------PPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 1148 KKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADG 1207
             KGE G  G PGP  I+   G +GE G  G  G  G++G+ GVPG       PG  G  G
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGM------PGLKGLKG 985

Query: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 1267
            + G AGPPG +G  G  G PG  G  G+PG  G  G  G  GK G  G PG+AG PGLPG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG 1327
              G +G  G  G++ +   PGP G +G  GLPG  G  G+ G  GP G  GP GP G PG
Sbjct: 1046 IHGLQGDKGEPGYS-EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG 1387
              GSPG PG+PGP G  G KG KG  G PG+ G  G  G PG PG  G+ G +G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 1388 EPGFKGE----RGDPGIKGDKGPPGGKGQ---PGDPGIPGHKGHTGLMGPQG-------- 1432
              G KGE    R  PG +G+ G  G KG    PG PG+PG KG  G  GP+G        
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 1433 ---------LPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYL 1483
                     +PG+ G  GPPG  G PG PG  G   S     +  +  +G          
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284

Query: 1484 LAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543
               M P     + G PG PGP G  G  G  G  GE G PG  G  GP GPIGPKG  G 
Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344

Query: 1544 KGDPGA-PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPP 1602
            +GDPG    + L G  GPPG PG+PG  G  + G PG PG  G  GP G PG  G PG P
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQG--EPGPPGPPGNLGPCGPRGKPGKDGKPGTP 1402

Query: 1603 G 1603
            G
Sbjct: 1403 G 1403



 Score =  848 bits (2191), Expect = 0.0
 Identities = 519/1182 (43%), Positives = 606/1182 (51%), Gaps = 151/1182 (12%)

Query: 524  FGQGEKGEKGSLGLPGPPGRDGSKGMRGE---PGELGEPGLPGEVGMRGPQGPPGLPGPP 580
            F  G KGEKG  G PGPPG  G KG  G    PG  G  G PG  G+ G +G  G+ G P
Sbjct: 40   FCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 581  GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640
            G  G+PGL       GT G  G  GL G PG  G  G+QG PG  G  G  G  G  G  
Sbjct: 100  GFSGSPGL------PGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLK 153

Query: 641  GPPGVPGSVVQQE-GLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD---GPPGLQGLRG 696
            G  G P      E   KG+ G PG  G QG PGPPG  GP+GP G     G PG  G RG
Sbjct: 154  GQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRG 213

Query: 697  KKGDMGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPP 746
             KG MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPP
Sbjct: 214  PKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPP 273

Query: 747  GPTGPPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAG 804
            GP+G PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G
Sbjct: 274  GPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP----H 860
              G PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     
Sbjct: 334  DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 861  PRMPGEQGPKGEKGDP-----GLPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGA 911
            P  PG +G KGE+G P     G PG PG  G PG  G  GP GPPG     KG  G HG 
Sbjct: 394  PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 912  PGAAGNPGAPGHVGAPGP-----------SGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            PG  G+PG PG  G  G             GPPG  G PGL G  G  G +G  G  G  
Sbjct: 454  PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 961  GSPGPVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSP---GLPGPLGT 1003
            GSPG  G  G PG PG  G PG KG+ GE             PGLRG P   GL G  GT
Sbjct: 514  GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGT 573

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPG 1063
                G        AL G+  KGD+G PG PGSPGS G    G AGPPG  GP G+ G  G
Sbjct: 574  PGVKGLPGPKGELALSGE--KGDQGPPGDPGSPGSPGP--AGPAGPPG-YGPQGEPGLQG 628

Query: 1064 SRGLPGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116
            ++G+PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D
Sbjct: 629  TQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGD 684

Query: 1117 ----CPPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP- 1166
                 P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G  
Sbjct: 685  PGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEP 744

Query: 1167 ----QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 1222
                 G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG
Sbjct: 745  AVAMPGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPG 801

Query: 1223 KEGPP-----GPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPP 1275
            ++GPP     GP+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G P
Sbjct: 802  EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861

Query: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 1335
            G +G  G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG P
Sbjct: 862  GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIP 921

Query: 1336 GEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 1392
            G  G  GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG K
Sbjct: 922  GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLK 981

Query: 1393 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP---GENGPVGPPGPPGQP 1449
            G +G PG  G  GP G  G  G+PG PG +G  G MG  G+P   G+ G +G PG  G+P
Sbjct: 982  GLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509
            G PG+ G           +Q + G+              P Y + +  RPGPPGP G  G
Sbjct: 1042 GLPGIHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPG 1074

Query: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPG 1562
            LPG  G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            I G PG PG+     PG PGP G  G  G  G+PGP G  G+
Sbjct: 1135 IRGPPGLPGF-----PGSPGPMGIRGDQGRDGIPGPAGEKGE 1171



 Score =  834 bits (2154), Expect = 0.0
 Identities = 524/1235 (42%), Positives = 619/1235 (50%), Gaps = 198/1235 (16%)

Query: 544  DGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE 603
            DG+KG +GE G  G PG PG+ G  GP+G PG  GP G  G PGL G +G +G  G  G 
Sbjct: 42   DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101

Query: 604  RGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQG 660
             G  G PG PG+TG  G    PG SG  G QG  G  G  G PG+PG+     GLKG++G
Sbjct: 102  SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAA----GLKGQKG 157

Query: 661  AP-----------------GPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRGKKGD 700
            AP                 G  G QG PGPPG  GP+GP G  G    PG  G RG KG 
Sbjct: 158  APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGH 217

Query: 701  MGP-----PGIPGLLGLQGPPGPPG-----VPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
            MG       G  G+ GL GPPGPPG     + GP       G  G+ G  G+PGPPGP+G
Sbjct: 218  MGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277

Query: 751  PPGKD--GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808
             PG+      G PG PG +G+PG+ G  G PG  G++G  G  GL G  G KG+ G  G 
Sbjct: 278  LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGP 337

Query: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH----PRMP 864
            PGF G         EKG+ G PG  G RG +G  GP+GPPG+PG+     P     P  P
Sbjct: 338  PGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWP 397

Query: 865  GEQGPKGEKGDPG-----LPGEPGLQGRPGELGPQGPTGPPG----AKGQEGAHGAPGAA 915
            G +G KGE+G PG      PG PG  G PG  G  GP GPPG     KG  G HG PG  
Sbjct: 398  GLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYL 457

Query: 916  GNPGAPGHVGAPGPSG-----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964
            G+PG PG  G  G  G           PPG  G PGL G  G  G +G  G  G  GSPG
Sbjct: 458  GSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPG 517

Query: 965  PVGPRGDPGAPGLPGPPG-KGKDGE-------------PGLRGSPG---LPGPLGTKAAC 1007
              G  G PG PG  G PG KG+ GE             PGLRG PG   L G  GT    
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVK 577

Query: 1008 GKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067
            G        AL G+  KGD+G PG PGSPGS G  G   AGPPG  GP G+ G  G++G+
Sbjct: 578  GLPGPKGELALSGE--KGDQGPPGDPGSPGSPGPAG--PAGPPG-YGPQGEPGLQGTQGV 632

Query: 1068 PGFPGPQGPAGRDG-------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC--- 1117
            PG PGP G AG  G        PG PG  GPPG PG      PG    L K  C D    
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGK--CGDPGLP 688

Query: 1118 -PPGPPGLPGL-----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQ---- 1167
             P G PG+PG+     PG KGD+G PG  G  G  GK GE G PG PG PG  G      
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 1168 -GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
             G  G  G  GE G  G+ G  G+PG    PG PG PG +G+ G  G PG  G PG++GP
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGL---PGLPGTPGNEGLDGPRGDPGQPGPPGEQGP 805

Query: 1227 PG-----PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG--EPGLPGPEGARGPPGFKG 1279
            PG     P+G  GLPG+ G +G++GR GK GP G+PG  G    G PG  G+ G PG +G
Sbjct: 806  PGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQG 865

Query: 1280 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
              G  G  G  G  G +G PG++G+ G  G  G  GP GP G  G PG+ GSPG PG  G
Sbjct: 866  EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKG 925

Query: 1340 PSGTPGQKGSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
              GTPG KG +G+ G+PG   +   +G +G PG  G  G PG++G  G PG PG KG +G
Sbjct: 926  QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG 985

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPG---ENGPVGPPGPPGQPGFPG 1453
             PG  G  GP G  G  G+PG PG +G  G MG  G+PG   + G +G PG  G+PG PG
Sbjct: 986  LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045

Query: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513
            + G           +Q + G+              P Y + +  RPGPPGP G  GLPG 
Sbjct: 1046 IHG-----------LQGDKGE--------------PGYSEGT--RPGPPGPTGDPGLPGD 1078

Query: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQ 1566
             G  GE G+PG  G  GP+GP G  G  G+ G PG PG        G++G +GPPGI G 
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138

Query: 1567 PGEPGY-------------AKDGLPGIPGPQGETG----------------------PAG 1591
            PG PG+              +DG+PG  G +GETG                        G
Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198

Query: 1592 HPGLPG---PPGPPGQCDPSQCAYFASLAARPGNV 1623
             PGLPG     G  G   P+    F      PG +
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233



 Score =  801 bits (2070), Expect = 0.0
 Identities = 491/1105 (44%), Positives = 559/1105 (50%), Gaps = 119/1105 (10%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGP--MGLPGPKGDIGAIGPVGAP 510
            P  PP  P +PGS + G           G KGE G  G   MG PG  G  G+ G  G+P
Sbjct: 373  PSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSP 432

Query: 511  GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKG-----------------MRGEP 553
            GP G  GD+       G+ G  G LG PG PG DG KG                 + G P
Sbjct: 433  GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGE----RGLDGF 609
            G  G  G+PG  G  G +G PG PG  G  G PG  G +G+ G +GEKGE     G  G 
Sbjct: 493  GLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGV 552

Query: 610  PGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG 669
            PG PG  GQ GR G  G+ G  G KG  GP G   + G        KG+QG PG  G  G
Sbjct: 553  PGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE-------KGDQGPPGDPGSPG 605

Query: 670  APGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG-------LQGPPGPPGVP 722
            +PGP G  GP G  G  G PGLQG +G  G  GPPG  G  G       + GPPGPPG P
Sbjct: 606  SPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPP 664

Query: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPN--GPPGPPGTKGEPGERGEDGLPG 780
            G PGP G PG+PG +G  G PG PGP G PG  G    GPPGP G +G PG +G  G PG
Sbjct: 665  GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 781  KPGLRGEIGEQGLAGRPGEKGEA--GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
            K G  G  G+ GL G  GE   A  G PG PGFPG RG  G+ GE G  GLPGL G  G 
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGN 784

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP-----KGEKGDPGLPGEPGLQGRPGELGP 893
            +G  GP G PG PG           PGEQGP     +G +G  GLPG  GL+G+ G  G 
Sbjct: 785  EGLDGPRGDPGQPGP----------PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953
             GP G PG  G + + G PG  G+PG PGH G  GP G  G  G PG+ G PG+DG  G 
Sbjct: 835  TGPKGDPGIPGLDRS-GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGM 893

Query: 954  KGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPG---LPGPLGTKAACG- 1008
             G  G  G PGP G  G PG  G PG PG KG+ G PG +G  G    PGP       G 
Sbjct: 894  MGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGD 953

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP 1068
            K         G    KG+RG PG+PG  G +G PG   AGPPGP G  G  G+PG  GL 
Sbjct: 954  KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPG--PAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 1069 GFPGPQGPAGRDGAPGN------PGERGPPGKPGLSSLLS----PGDINLLAKDVCNDCP 1118
            G PG  G  G  G+ G       PG  G PG PG+  L      PG       +     P
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPG-----YSEGTRPGP 1066

Query: 1119 PGPPGLPGLPGF---KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGA 1175
            PGP G PGLPG    KG+ G PG PG  G  G +G  G PG PG PG  GP G  G +G 
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126

Query: 1176 DGEVGQKGDQGHPGVPGFMGPPGNPG---PPGADGIAGAAG----------PPGIQGSPG 1222
             G +G  G +G PG+PGF G PG  G     G DGI G AG          PPG +G+PG
Sbjct: 1127 KGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPG 1186

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP-----EGARGPPGF 1277
             +G  G +G  G PG+PG +G  G  G  GP G  G  G PGLPG       G RGPPG 
Sbjct: 1187 AQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGS 1246

Query: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337
            +G  G  G PGP G S  +G+ G +G     G  GP GP G  G  GPPG+ G+PG+PG 
Sbjct: 1247 RGSPGAPGPPGPPG-SHVIGIKGDKG---SMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG---------VPGKPGE 1388
            PGP G PG +G  G  G  G PGFLG  GPPG  G KG PG  G         +PG PG 
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 1389 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
            PG  GE G  G  G  GPPG  G  G  G PG  G  G  GP G  G  G  G PGP G 
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS 1422

Query: 1449 PGFPGLRGE-----SPSMETLRRLI 1468
             G PGL+G+     SP+  T R  +
Sbjct: 1423 DGLPGLKGKRGDSGSPATWTTRGFV 1447



 Score =  621 bits (1602), Expect = e-177
 Identities = 381/879 (43%), Positives = 448/879 (50%), Gaps = 121/879 (13%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
            P G   V+    P PP PP  P  PG +            P G  G +G  G  GLPGP 
Sbjct: 644  PRGELSVSTPV-PGPPGPPGPPGHPGPQG-----------PPGIPGSLGKCGDPGLPGPD 691

Query: 499  GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE-----P 553
            G+ G  G +G PGP G KGD G  P  +G  G  G +G PG PG+ G  G +GE     P
Sbjct: 692  GEPGIPG-IGFPGPPGPKGDQGF-PGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMP 749

Query: 554  GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGK- 612
            G  G PG PGE G  G  G  GLPG PG  G PG +G  G +G  G+ G  G  G PG+ 
Sbjct: 750  GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 613  -PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671
              G  G QG PG +G+ G QG +G  GP G PG+PG  + + G  GE G+PG  GHQG  
Sbjct: 810  IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG--LDRSGFPGETGSPGIPGHQGEM 867

Query: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731
            GP G RG  G  G  GPPG  G+      +G  G PG +   GPPGPPG PG PG  GSP
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGV------IGMMGFPGAI---GPPGPPGNPGTPGQRGSP 918

Query: 732  GLPGEIGFPGKPGPPGPTGPPGKDGPN---------GPPGPPGTKGEPGERGEDGLPGKP 782
            G+PG  G  G PG  G  G  G  GP+         G PG  G  G PGE+G  G+PG P
Sbjct: 919  GIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMP 978

Query: 783  GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842
            GL+G  G  G AG PG +G+ G  G PG PG+RG  G     G +G+PG KG RG  G  
Sbjct: 979  GLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSM---GNMGMPGSKGKRGTLGFP 1035

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG-----DPGLPGEPGLQGRPGELGPQGPT 897
            G AG PGLPG          + G QG KGE G      PG PG  G  G PG++G +G  
Sbjct: 1036 GRAGRPGLPG----------IHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 957
            G PG  G  G  G  GA G+PG+P   G PG  GP G +G  G++G  G  G RG  G  
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSP---GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLP 1142

Query: 958  GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA 1017
            G  GSPGP+G RGD G  G+PGP   G+ GE GL  +P  PGP G               
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGP--AGEKGETGLLRAP--PGPRGNP------------- 1185

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPG-------IGVAGPPGPSGPP--------GDKGSP 1062
             G Q  KGDRGAPG PG PG +G  G        G+ G PGP G P        G++G P
Sbjct: 1186 -GAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPP 1244

Query: 1063 GSRGLPGFPGPQGPAGR--------DGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            GSRG PG PGP GP G          G+ G+PG +GPPG  G   +  PG +        
Sbjct: 1245 GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG--DMGPPGRL-------- 1294

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
                 G PG PGLPG +GD G  G PG +G +G  G  G  G PGP G  GP G +G+ G
Sbjct: 1295 -----GAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
                +   G  G PG PG  G  G PGPPG  G  G  GP   +G PGK+G PG  GP+G
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP---RGKPGKDGKPGTPGPAG 1406

Query: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
              G  G +G+ G  G  G PG  GK G+ G P     RG
Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  349 bits (895), Expect = 1e-95
 Identities = 240/647 (37%), Positives = 274/647 (42%), Gaps = 184/647 (28%)

Query: 1133 DKGVPGKPGREGTEGKKGEAGPPGLP------GPPGIAGPQGSQGERGADGEVGQKGDQG 1186
            DKG     G +G +G+KG  GPPG P      GP G+ GPQG +G  G  G  G KG +G
Sbjct: 35   DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246
              G+PGF G PG PG PG  G  G  G PG  GS G++G PG  G  G PGIPG  G +G
Sbjct: 95   ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 1247 RDGK-----------------PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            + G                  PG PG  G  G PG PGP G  GPPGF G  G  G  GP
Sbjct: 155  QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 1290 RGESG--AMGLPGQEGLPGKDGDTGP--------TGPQGPQGPRGPPGKNGSPGSPGEPG 1339
            +G  G   +G  G+ G+ G  G  GP        TGP      +G  G  G+ G PG PG
Sbjct: 215  KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 1340 PSGTPGQK--GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD 1397
            PSG PG+     KG  G PGL G  G  G PG PG +GV G  G PG  GE G KG++GD
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 1398 ---------------------------PGIKGDKGPPGGKGQPGDPGIPGHK-------- 1422
                                       PG +G +GP G  G PG PG PG          
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 1423 -----------------------GHTGLMGPQGLPGENGPVGPP-------GPPGQPGFP 1452
                                   G  G  G  GLPG  GP GPP       GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 1453 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 1512
            G  G SP +  +        G + E  L  L  Q P  Y+    G PG PG  G  G+PG
Sbjct: 455  GYLG-SPGIPGVD-------GPKGEPGL--LCTQCP--YIPGPPGLPGLPGLHGVKGIPG 502

Query: 1513 R---AGPMGEPGRPGQGGLEG----------------------PSGPIGPKGERGAKGD- 1546
            R   AG  G PG PG  GL G                      P G +G  G+ G +G  
Sbjct: 503  RQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQP 562

Query: 1547 --------PGAPGV-------------GLRGEMGPPGIPGQPGEPGYA------------ 1573
                    PG PGV             G +G+ GPPG PG PG PG A            
Sbjct: 563  GRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQG 622

Query: 1574 ------KDGLPGIPGPQGETGPAGH-------PGLPGPPGPPGQCDP 1607
                    G+PG PGP GE GP G        PG PGPPGPPG   P
Sbjct: 623  EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669



 Score =  312 bits (799), Expect = 2e-84
 Identities = 190/437 (43%), Positives = 218/437 (49%), Gaps = 71/437 (16%)

Query: 449  TEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508
            T P PP P   P  PG                    +MG  G MG PGP G +G  GP G
Sbjct: 1062 TRPGPPGPTGDPGLPG--------------------DMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 509  APGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMR 568
            APG  G  G  G  P   G+ G KG  GL GPPG      +RG PG  G PG PG +G+R
Sbjct: 1102 APGSPGSPGLPG-KPGPHGDLGFKGIKGLLGPPG------IRGPPGLPGFPGSPGPMGIR 1154

Query: 569  GPQGPPGLPGPPGRVGAPGL----QGERGEKGTRGEKGERGLDGFPGKPG---------- 614
            G QG  G+PGP G  G  GL     G RG  G +G KG+RG  GFPG PG          
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 615  --DTGQQGRPGPSGVAG-----------PQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661
               TG +G PGP G+ G           P G +G  G  GPPG PGS V   G+KG++G+
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI--GIKGDKGS 1272

Query: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD---MGPPGI------PGLLGL 712
                GH G  GPPG  G +GP GR G PG  GL G +GD    G PG+      PG LG 
Sbjct: 1273 ---MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS 1329

Query: 713  QGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             GPPGP G  GPPG  G PG    I  PG PGPPG  G PG  G  GPPGPPG  G  G 
Sbjct: 1330 IGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGP 1389

Query: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
            RG+ G  GKPG  G  GE+   G  G KGE G  G+ G PG++G++GD G        G 
Sbjct: 1390 RGKPGKDGKPGTPGPAGEK---GNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446

Query: 833  KGDRGEKGEAGPAGPPG 849
               R  +  A P+ P G
Sbjct: 1447 VFTRHSQTTAIPSCPEG 1463



 Score =  307 bits (786), Expect = 6e-83
 Identities = 210/538 (39%), Positives = 243/538 (45%), Gaps = 114/538 (21%)

Query: 1146 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205
            +G KGE G  G PGPPG      S G++G  G  G  G QG  G PG       PG  G+
Sbjct: 42   DGAKGEKGEKGFPGPPG------SPGQKGFTGPEGLPGPQGPKGFPGL------PGLTGS 89

Query: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265
             G+ G +G PG  GSPG  G PG  GP GL G+P   G  G  G+ G PG PG  G PG+
Sbjct: 90   KGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVP---GCSGSKGEQGFPGLPGTLGYPGI 146

Query: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325
            PG  G +G  G      D        E  A G PG  G PG  G  GP G  GP GP GP
Sbjct: 147  PGAAGLKGQKGAPAKEEDI-------ELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP 199

Query: 1326 PGKNGSPGSPGEPGPSGTPGQK--GSKGENGSPGLPGFLGPRGP--------------PG 1369
            PG  G PG+ G  GP G  G++  G KGE G  GL G  GP G                G
Sbjct: 200  PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259

Query: 1370 EPGEKGVPGKEGVPGKPGEPGF-----KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
            E G+KG  G+ G PG  G PG      KG  GDPG++G  G  G  G PG  G+ G++G 
Sbjct: 260  EKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGF 319

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             GLMG  G+ G+ G +GPPG          RG +   +T +                   
Sbjct: 320  PGLMGEDGIKGQKGDIGPPG---------FRGPTEYYDTYQE------------------ 352

Query: 1485 AQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG-----RPGQGGLEGPSGPIGPKG 1539
                    K  +G PGPPGP G  G  G +GP G PG     RPG  G  G  G  G KG
Sbjct: 353  --------KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 1540 ERG-----AKGDPGAPGV----GLRGEMGPPGIPGQ-------PGE---PGY-AKDGLPG 1579
            ERG     A G PG+PG     GL G  GPPG PG        PG+   PGY    G+PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 1580 IPGPQGETG-----------PAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            + GP+GE G           P G PGLPG  G  G       A        PGN   P
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLP 522



 Score =  242 bits (618), Expect = 2e-63
 Identities = 169/425 (39%), Positives = 191/425 (44%), Gaps = 102/425 (24%)

Query: 1271 ARGPPGFKG----HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            A  P   KG      G     G +GE G  G PG  G PG+ G TGP G  GPQGP+G P
Sbjct: 22   AAAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP 81

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  GS G  G SG PG  GS    G PG PG  GP G  G PG  G  G++G PG P
Sbjct: 82   GLPGLTGSKGVRGISGLPGFSGSP---GLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLP 138

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGK-----GQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
            G  G+ G  G  G+KG KG P  +        GDPG+PG  G  GL GP G P   GPVG
Sbjct: 139  GTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFP---GPVG 195

Query: 1442 PPGPPGQPGFPGLRG-ESPSMETLRRLIQEELGKQLETRLAYLLAQM-PPAYM------- 1492
            PPGPPG  GFPG  G   P      R+I    G + E  +  L     PP  +       
Sbjct: 196  PPGPPGFFGFPGAMGPRGPKGHMGERVI----GHKGERGVKGLTGPPGPPGTVIVTLTGP 251

Query: 1493 ------------KSSQGRPGPPGP-----------------------PGKDGLPGRAGP- 1516
                        K + G PGPPGP                       PGKDG+PG  G  
Sbjct: 252  DNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSE 311

Query: 1517 -----MGEPGRPGQGGLEGPSGPIGPKGERG---------AKGDPGAPGV----GLRGEM 1558
                  G PG  G+ G++G  G IGP G RG          KGD G PG     G RG  
Sbjct: 312  GVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQ 371

Query: 1559 GPPGIPGQPGEPGYAKDGL------PGIPGPQGETGP--------------AGHPGLPGP 1598
            GP G PG PG PG ++ GL      PG+ G +GE G               AG PGLPG 
Sbjct: 372  GPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGS 431

Query: 1599 PGPPG 1603
            PGPPG
Sbjct: 432  PGPPG 436


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  892 bits (2305), Expect = 0.0
 Identities = 562/1306 (43%), Positives = 658/1306 (50%), Gaps = 176/1306 (13%)

Query: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPG------PKGDIGAI 504
            P PP  P     PG E +G +  +      G  G  G  GP GLPG      P G  G  
Sbjct: 147  PGPPGLPGMKGDPG-EILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPP 205

Query: 505  GPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE 564
            GP G PGP GEKG +G+    QG KG+KG  G+ GPPG  G   ++    E G+    GE
Sbjct: 206  GPPGPPGPPGEKGQMGLS--FQGPKGDKGDQGVSGPPGVPGQAQVQ----EKGDFATKGE 259

Query: 565  VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624
             G +G  G  G+PG  G  G PG  G RG+ G  G+KGE+G  GFPG+PG       PG 
Sbjct: 260  KGQKGEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPG------YPGL 312

Query: 625  SGVAGPQGEKGDVGPAGPPGVPGSV--VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP 682
             G  GPQGEKG+ GP GPPG+      + ++G +G  G PGPRG  G  G PG  G  GP
Sbjct: 313  IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372

Query: 683  EG-----RDGPPGLQGLRGKKGDMGPPG--IPGLLGLQGPPGPPGVPGPPG--------- 726
             G     + G PG  G RG+KGD G PG  +PG  G  G PGPPG PGPPG         
Sbjct: 373  PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432

Query: 727  ------PG--GSPGLPGEIGFPGK-------------------PGPPGPTGPPGKDGPNG 759
                  PG  G PG+PG+ GF G+                    GPPGP GPPG+ G  G
Sbjct: 433  ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492

Query: 760  PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE-------KGEAGLPGAPGFP 812
             PG  G +G PG  G  G+PG  G  G IG+ G  G PGE       KG+ G PG PG P
Sbjct: 493  QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQP 552

Query: 813  GVRGEKGDQGEKGELGLPGLKGDRGE---KGEAGPAGPPGLPGTTS-LFTPHPRMPGEQG 868
            G+ G  G  G  G  GLPG KG  G    KGE GP G  G PG+      P P   G  G
Sbjct: 553  GMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAG 612

Query: 869  PKGEKGDPGLPGEPGLQGRPGELGPQGPT----GPPGAKGQEGAHGAPGAAGNPGAPGHV 924
            P G+KG  G PG PG  G PG  G  G      GPPGA+G  G+ G PG  G+ G PG  
Sbjct: 613  PIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTP 672

Query: 925  GAPGPSGPPGSVGAPGLR--GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 982
            G PG  G  G+VG PG+   G PG  G  G  G  G  G+PG  G  G PG PG+ G  G
Sbjct: 673  GRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKG 732

Query: 983  KGKDGEPGLRGSPGLPGPLGTKAACGKVR----GSENCALGGQCVKGDRGAPGIPGSPGS 1038
            +   G PGL+G PGLPG  GT    G +       E+ A+G   ++G RG PG PG PGS
Sbjct: 733  EPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGS 792

Query: 1039 RGDPGIGVAGPPGPSGPPGDKGSPG---------SRGLPGFPG-----PQGP-------- 1076
             G PG+   GPPG  GPPG +G PG          +G PGFPG     P+G         
Sbjct: 793  VGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPG 852

Query: 1077 -AGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKG 1135
              G+ G PG PG++G PG PG     S G++ ++         PGP G PGLPG KGD G
Sbjct: 853  ITGQSGLPGLPGQQGAPGIPGFPG--SKGEMGVMGTPG-QPGSPGPVGAPGLPGEKGDHG 909

Query: 1136 VPGKPGREGTEGKKGEAGPPGLPGPPG---------IAGPQGSQGERGADGEVGQKGDQG 1186
             PG  G  G  G KG+ G  GLPG PG         + G +G QGE+G  G +G+KG +G
Sbjct: 910  FPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRG 969

Query: 1187 HPGVPGF------MGPPGNPGPPGADGIAGAAGPPGIQG------------SPGKEGPPG 1228
             PG PG        G PG PGP G  GI+G  G PG+ G            +PG++G PG
Sbjct: 970  DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPG 1029

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPPGE--PGKAGEPGLPGPEGARGPPGFKGHTGDSGA 1286
              GP G PG+PG++G +G  G+ GPPG   PG  GE G  G  G  G PG KG  G  G 
Sbjct: 1030 IPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI 1089

Query: 1287 PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ 1346
            PG  G  G  G PG  G PG  G  G  G +G  G  G PG  G  G PG PGP+G  GQ
Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQ 1149

Query: 1347 KGSKGENGSPGLPGFLGPRGPPGEPGE--KGVPGKEGVPGKPGEPGFKGERGDPGIKGDK 1404
            KG   E GS G+PG  G +G PG PG    G PG +G  G  GE GF G  G PGI G K
Sbjct: 1150 KG---EPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSK 1206

Query: 1405 G------PPGGKGQPGDPGIPGH--KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456
            G      PPG +GQPG PG PGH  +G  G  GPQG PG  G  GP GPPG PG  G++G
Sbjct: 1207 GEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKG 1266

Query: 1457 E--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG---PPGKDGLP 1511
            +  +P        +    G      +  +         K   G PG PG   P G  GL 
Sbjct: 1267 DKGNPGWPGAPG-VPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQ 1325

Query: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGP----KGERGAKGDPGAPGV-GLRGEMGPPG---- 1562
            G  G  G+ G PG  GL GP GP GP    KGE G  G  G PG+ GL+G  GP G    
Sbjct: 1326 GIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGV 1385

Query: 1563 -----IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
                 IPG PG PG+  DG PG  G  G  GP G  G PGPPGP G
Sbjct: 1386 TGLVGIPGPPGIPGF--DGAPGQKGEMGPAGPTGPRGFPGPPGPDG 1429



 Score =  890 bits (2301), Expect = 0.0
 Identities = 568/1359 (41%), Positives = 664/1359 (48%), Gaps = 272/1359 (20%)

Query: 476  CSCPA--GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKG 533
            C C    G+KGE G+ G  G+ G  G  G  GP G PG KG+ G+ G+ P  +G +G  G
Sbjct: 39   CDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGL-PGTKGTRGPPG 97

Query: 534  SLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERG 593
            + G PG PG  G  G  G PG  G PG  G  G RGP GPPGLPG  G  G PGL G +G
Sbjct: 98   ASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKG 157

Query: 594  EKG----------TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA--------------- 628
            + G           +GE+G  G+ G PG PG  G QG  GP G                 
Sbjct: 158  DPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEK 217

Query: 629  --------GPQGEKGDVGPAGPPGVPGSV-VQQEG---LKGEQGAPGPRGHQGAP--GPP 674
                    GP+G+KGD G +GPPGVPG   VQ++G    KGE+G  G  G QG P  G  
Sbjct: 218  GQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEK 277

Query: 675  GARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP------G 728
            G  G  GP G+ G  G +G +G  G  G PG PGL+G QGP G  G  GPPGP       
Sbjct: 278  GEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGT 337

Query: 729  GSPGLPGEIGFPGKPGP---PGPTGPPGKDGPNGPPGPP-----GTKGEPGERGE----- 775
            G  G  GE G+PG PGP   PGP G PG  G  GPPG P     G  G PGERGE     
Sbjct: 338  GPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRG 397

Query: 776  ------------DGLPGKPGLRGEIGEQGLA--------GRPGEKGEAGLPGAPGFPGVR 815
                        DGLPG PG  G  G+ G          G PG++G  G+PG PGF G  
Sbjct: 398  FPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEI 457

Query: 816  GEKGDQGEK-------------------GELGL---PGLKGDRGEKGEAGPAGPPGLPGT 853
            GEKG +GE                    GE+G    PG KGDRG  G  G AG PG  GT
Sbjct: 458  GEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGT 517

Query: 854  TSLFTPHPRMPGEQGP-------KGEKGDPGLPGEPGLQGR------------------- 887
              L    P   GE G        KG+KGDPG PG+PG+ GR                   
Sbjct: 518  PGLI-GQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSP 576

Query: 888  -----PGELGPQGPTGPPGAKGQEGAHGAP-----------GAAGNPGAPGHVGAPGPS- 930
                  GE GP G  G PG++G  G  G P           G AG PG PG  G PGP  
Sbjct: 577  GSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKG 636

Query: 931  ---------GPPGSVGAPGLRGTPGKDGER------------GEKGAAGE---------- 959
                     GPPG+ G PG  G PG  G+R            GEKGA G+          
Sbjct: 637  EPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG 696

Query: 960  ----EGSPGPVGPRGDPGAP---GLPGPPG-KGKDGE-----PGLRGSPGLPGPLGTKAA 1006
                +G PG +GP G PG P   GLPG PG +G+ GE     PGL+G PGLPG  GT   
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 1007 CGKVR----GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSP 1062
             G +       E+ A+G   ++G RG PG PG PGS G PG+   GPPG  GPPG +G P
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 1063 ---------GSRGLPGF-----PGPQGP---------AGRDGAPGNPGERGPPGKPGLSS 1099
                     G +G PGF     PGP+G           G+ G PG PG++G PG PG   
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876

Query: 1100 LLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG 1159
              S G++ ++         PGP G PGLPG KGD G PG  G  G  G KG+ G  GLPG
Sbjct: 877  --SKGEMGVMGTP-GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPG 933

Query: 1160 PPG---------IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 1210
             PG         + G +G QGE+G  G +G+KG +G PG PG  G  G  G PG     G
Sbjct: 934  KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQ---PG 990

Query: 1211 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 1270
              G PGI G+PG  G PGP+G  G  G+PG  G++G  G PGP G PG  G+ G  G +G
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050

Query: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 1330
              GPPG        G PG RGE G  G+    G PG  G+ G  G  G  G  G PG  G
Sbjct: 1051 QAGPPGI-------GIPGLRGEKGDQGI---AGFPGSPGEKGEKGSIGIPGMPGSPGLKG 1100

Query: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 1390
            SPGS G PG  G PG+KG KG  G  G+PG  G  G PG PG  G  G++G PG  G PG
Sbjct: 1101 SPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPG 1160

Query: 1391 FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP---GENGPVGPPGPPG 1447
              GE+G+PG+ G +G PG  G  GD G  G  G  GL G  G+P   GE G +GPPGP G
Sbjct: 1161 SAGEKGEPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQG 1219

Query: 1448 QPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK 1507
            QPG PG  G +       R  Q + G             +P        G PGP GPPG 
Sbjct: 1220 QPGLPGSPGHATEGPKGDRGPQGQPG-------------LP--------GLPGPMGPPGL 1258

Query: 1508 DGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1567
             G+ G  G  G PG PG  G+ GP G  G +G  G  G PG    G +G+MGPPG+PG  
Sbjct: 1259 PGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGI--TGSKGDMGPPGVPGFQ 1316

Query: 1568 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606
            G  G    GL GI G QG+ G  G  GLPGPPGPPG  D
Sbjct: 1317 GPKGL--PGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYD 1353



 Score =  876 bits (2264), Expect = 0.0
 Identities = 549/1266 (43%), Positives = 637/1266 (50%), Gaps = 212/1266 (16%)

Query: 505  GPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGE 564
            G     G KG+KG+ G+        G +G +G PG  G +G +G  G+ G+ GEPGLPG 
Sbjct: 37   GKCDCHGVKGQKGERGL-------PGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGT 89

Query: 565  VGMRGPQGPPGLPGPPGRVGAPGLQGERGE---KGTRGEKGERGLDGFPGKPGDTGQQGR 621
             G RGP G  G PG PG  G PG  G  G     G  G KGERG  G PG PG  G  G 
Sbjct: 90   KGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGP 149

Query: 622  PGPSGVAGPQGE----------KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAP 671
            PG  G+ G  GE          KG+ G  G PG PG      GL G QG  GP G  G P
Sbjct: 150  PGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPG----PPGLPGLQGPVGPPGFTGPP 205

Query: 672  GPPGARGPIGPEGR-----------------DGPPGLQG-----------LRGKKGDMGP 703
            GPPG  GP G +G+                  GPPG+ G            +G+KG  G 
Sbjct: 206  GPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGE 265

Query: 704  PGIPGL--LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP---GPTGPPGKDGPN 758
            PG  G+  +G +G PG PG  G PG  G  G  G  GFPG+PG P   G  GP G+ G  
Sbjct: 266  PGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEA 325

Query: 759  GPPGPPGT---KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP-----GAPG 810
            GPPGPPG     G  GE+GE G PG PG RGE G +G  G PG+ G  GLP     GAPG
Sbjct: 326  GPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPG 385

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG-TTSLFTPHPRMPGEQGP 869
            FPG RGEKGD+G  G   LPG  G  G  G  G  GPPG PG T  +    P  PG+QGP
Sbjct: 386  FPGERGEKGDRGFPG-TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGP 444

Query: 870  KGEKGDPGLPGEPGLQGRPGE----------LGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919
             G  G PG  GE G +G+ GE           GP GP GPPG  G  G  GA G  G PG
Sbjct: 445  PGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPG 504

Query: 920  APGHVGAPGPSGPPGSVGAPGLRGTPGK-------DGERGEKGAAGEEGSPGPVGPRGDP 972
              G  G PGP G PG +G PG +G PG+        G++G+ G  G+ G  G  G  G  
Sbjct: 505  RDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRD 564

Query: 973  GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI 1032
            G PGLPGP  KG  G  GL+G  G PG +G   + G          G     GD+G  G 
Sbjct: 565  GHPGLPGP--KGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGF 622

Query: 1033 PGSPGSRGDPGIGVAGPPGP----SGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN--- 1085
            PG PGS G P  G  G PG      GPPG +G PGS   PGFPGPQG  G  G PG    
Sbjct: 623  PGGPGSPGLP--GPKGEPGKIVPLPGPPGAEGLPGS---PGFPGPQGDRGFPGTPGRPGL 677

Query: 1086 PGERGPPGKPGLSSLLSPG--DINLLAKDVCNDCPPGPPGLPGLP--------------G 1129
            PGE+G  G+PG+     PG   ++ L  D+     PG PG  GLP              G
Sbjct: 678  PGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVG 737

Query: 1130 FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG 1189
              G KG+PG PG  GT G+KG  G PG+PG  G  GP G QG RG  G  G  G  G PG
Sbjct: 738  LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG 797

Query: 1190 VPGFMGPPGNPGPPGADGIAGAAGPPGI-----------------QGSPGKEGPPGPQGP 1232
            VPG +GPPG  GPPG  G  G +GPPGI                 +G  G +G PG  G 
Sbjct: 798  VPG-IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQ 856

Query: 1233 SGLPGIPGEEGKEGRDGKPGPPGE---PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            SGLPG+PG++G  G  G PG  GE    G  G+PG PGP GA G PG KG  G  G+ GP
Sbjct: 857  SGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGP 916

Query: 1290 RGESGAMGLPGQEGLPGK------------------DGDTGPTGPQGPQGPRGPPGKNGS 1331
            RG+ G  G  G  GLPGK                   G+ G  GP G +G RG PG  G 
Sbjct: 917  RGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGV 976

Query: 1332 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGP------PGEPGEKGV---PGKEGV 1382
            PG  G+ G  G PG KG  G +G+PG PG  GP+G       PG PGEKGV   PG +G 
Sbjct: 977  PGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGS 1036

Query: 1383 PGKPGEPGFKGERGD--------PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLP 1434
            PG PG+ G KGE+G         PG++G+KG  G  G PG PG  G KG  G+ G  G P
Sbjct: 1037 PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSP 1096

Query: 1435 GENGPVGPPGPPGQPGFPGLRGES--PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYM 1492
            G  G  G  G PG PG PG +G+   P ++ +  +  E              A +P    
Sbjct: 1097 GLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGE--------------AGLP---- 1138

Query: 1493 KSSQGRPGPPGP------PGKDGLPGRAGPMGEPGRPGQG--GLEGPSGPIGPKGERGAK 1544
                G PGP GP      PG DG+PG AG  GEPG PG+G  G  G  G  G KGE G  
Sbjct: 1139 ----GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFP 1194

Query: 1545 GDPGAPGV----GLRGEMGPP---GIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPG 1597
            G  G+PG+    G +G MGPP   G PG PG PG+A +G  G  GPQG+    G PGLPG
Sbjct: 1195 GLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ---PGLPGLPG 1251

Query: 1598 PPGPPG 1603
            P GPPG
Sbjct: 1252 PMGPPG 1257



 Score =  874 bits (2257), Expect = 0.0
 Identities = 543/1278 (42%), Positives = 633/1278 (49%), Gaps = 185/1278 (14%)

Query: 441  GPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500
            GP      T PP PP P  PP     Q+G    ++   P G+KG+ GV+GP G+PG +  
Sbjct: 194  GPVGPPGFTGPPGPPGPPGPPGEKG-QMG----LSFQGPKGDKGDQGVSGPPGVPG-QAQ 247

Query: 501  IGAIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEP 559
            +   G     G KG+KG+ G  G  G GEKGE G  G  G PG+DG KG +G PG  GEP
Sbjct: 248  VQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEP 307

Query: 560  GLPGEVGMRGPQGPPGLPGPPG------RVGAPGLQGERGEKGTRGEKGERGLDGFPGKP 613
            G PG +G +GPQG  G  GPPG        G  G +GERG  GT G +GE G  GFPG P
Sbjct: 308  GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLP 367

Query: 614  GDTGQQGRP-----GPSGVAGPQGEKGD-----------------VGPAGPPGVPGSVVQ 651
            G  G  G P     G  G  G +GEKGD                  GP G PG PG    
Sbjct: 368  GQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGY 427

Query: 652  QEGL-KGEQGAPGPRGHQGAPGPP----------------------GARGPIGPEGRDGP 688
              G+ + + G PG +G  G PG P                      G RGP GP+G  G 
Sbjct: 428  TNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGE 487

Query: 689  PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGL----------PGEIG 738
             G  G  G KGD G PG  G+ G+ GP G PG+ G PG  G PG            G+ G
Sbjct: 488  IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG 547

Query: 739  FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP- 797
            FPG+PG  G  G PG+DG  G PGP G+ G  G +GE G PG  G  G  G+ G  G P 
Sbjct: 548  FPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG 607

Query: 798  -------GEKGEAGLPGAPGFPGVRGEKGDQGE----------KGELGLPGLKGDRGEKG 840
                   G+KG+AG PG PG PG+ G KG+ G+          +G  G PG  G +G++G
Sbjct: 608  YGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRG 667

Query: 841  EAGPAGPPGLPGTT-SLFTPHPRMPGEQGPK------GEKGDPGLPGEPGLQGRPGELGP 893
              G  G PGLPG   ++  P    PG  GPK      G+ G PG PG PG  G PG  G 
Sbjct: 668  FPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGV 727

Query: 894  QGPTGPPGA--KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951
            QG  G PG    G +G  G PG  G PG  G +G PG  G  G++G PGL+G  G+ G  
Sbjct: 728  QGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPP 787

Query: 952  GEKGAAGEEGSP--GPVGPRGDPGA---PGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKA 1005
            G  G+ G  G P  GP G RG PG    PGL GPPG KG+ G PG  G   +PGP G K 
Sbjct: 788  GLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGL-DMPGPKGDKG 846

Query: 1006 ACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGS 1064
            A G    +    L G  + G +GAPGIPG PGS+G+ G+ G  G PG  GP G  G PG 
Sbjct: 847  AQGLPGITGQSGLPG--LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGE 904

Query: 1065 RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP--- 1121
            +G  GFPG  GP G  G  G+ G+ G PGKPG    +  G +     D       GP   
Sbjct: 905  KGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE 964

Query: 1122 ------PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP--------------- 1160
                  PG PG+PG  G  G PG+PG +G  G  G  G PGLPGP               
Sbjct: 965  KGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGE 1024

Query: 1161 ---PGIAGPQGSQGERGADGEVGQKGDQGHP--GVPGFMGPPGN------PGPPGADGIA 1209
               PGI GPQGS G  G  G  G+KG  G P  G+PG  G  G+      PG PG  G  
Sbjct: 1025 KGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEK 1084

Query: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 1269
            G+ G PG+ GSPG +G PG  G  G PG+PGE+G +G  G  G PG  G+AG PG PGP 
Sbjct: 1085 GSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGP- 1143

Query: 1270 GARGPPGFKGHTGDSGAPGPRGESGAMGLP-----------------GQEGLPGKDGDTG 1312
               GP G KG  G  G PG  GE G  GLP                 G+ G PG  G  G
Sbjct: 1144 --TGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPG 1201

Query: 1313 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 1372
              G +G QG  GPPG  G PG PG PG   T G KG +G  G PGLPG  GP GPPG PG
Sbjct: 1202 IPGSKGEQGFMGPPGPQGQPGLPGSPG-HATEGPKGDRGPQGQPGLPGLPGPMGPPGLPG 1260

Query: 1373 EKGVPGKEGVPGKPGEPGFKGERGD------PGIKGDKGPPGGKGQPGDPGIPGHKGHTG 1426
              GV G +G PG PG PG  G +GD      PGI G  G  G KG  G PG+PG +G  G
Sbjct: 1261 IDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKG 1320

Query: 1427 LMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQ 1486
            L G QG+ G+ G  G PG  G PG PG  G          +I+ E G         L   
Sbjct: 1321 LPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYD-------IIKGEPG---------LPGP 1364

Query: 1487 MPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGD 1546
              P  +K  QG PGP G  G  GL G  GP G PG  G  G +G  GP GP G RG  G 
Sbjct: 1365 EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP 1424

Query: 1547 PGAPGVGLRGEMGPPGIP 1564
            PG    GL G MGPPG P
Sbjct: 1425 PGPD--GLPGSMGPPGTP 1440



 Score =  816 bits (2109), Expect = 0.0
 Identities = 511/1177 (43%), Positives = 596/1177 (50%), Gaps = 185/1177 (15%)

Query: 450  EPPPPPPPQRPPTPGSE----------QIGFLKTINCSCPAGEKGEMGVAGPMGL---PG 496
            EP  P P  +P   G +          + G+   I    P GEKGE G  GP G+    G
Sbjct: 279  EPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTG 338

Query: 497  PKGDIGAIGPVGAPGPKGEKGDVGI-------GPFG------------QGEKGEKGSLG- 536
            P G+ G  G  G PGP+GE G  G        GP G             GE+GEKG  G 
Sbjct: 339  PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 398

Query: 537  ----LPGPPGRDGSKGMRGEPGELGEPGLPGEV-----GMRGPQGPPGLPGPPGRVGAPG 587
                LPGP GRDG  G  G PG  G+PG    +     G  G QGPPG+PG PG +G  G
Sbjct: 399  PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIG 458

Query: 588  LQGERGEK-------------GTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEK 634
             +G++GE              G +G  GE G  G PG  GD G  GR G +GV GPQG  
Sbjct: 459  EKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTP 518

Query: 635  GDVGPAGPPGVPGSVV---------------QQEGLKGEQGAPGPRGHQGAPGPPGARGP 679
            G +G  G  G PG                   Q G+ G  G+PG  GH G PGP G+ G 
Sbjct: 519  GLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGS 578

Query: 680  IGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGF 739
            +G +G  GPPG  G  G +GD GPPG PG  G  GP G  G  G PG  GSPGLPG  G 
Sbjct: 579  VGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGSPGLPGPKGE 637

Query: 740  PGK----PGPPGPTGPPGKDG---PNGPPGPPGTKGEPGERGEDGLPGKPGLR--GEIGE 790
            PGK    PGPPG  G PG  G   P G  G PGT G PG  GE G  G+PG+   G  G 
Sbjct: 638  PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP 697

Query: 791  QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE--------LGLPGLKGDRGEKGEA 842
            +G+ G PG+ G  G PG PGF G+ G  G QG+KGE         GLPGL G  G  GE 
Sbjct: 698  KGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEK 757

Query: 843  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE-----------PGLQGRPGEL 891
            G  G PG+PG      P    PG QG +GE G PGLPG            PG +G PG  
Sbjct: 758  GSIGVPGVPGEHGAIGP----PGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQ 813

Query: 892  GPQGPTGPPGAKGQEGAHGAPGA--------AGNPGAPGHVGAPGPSGPPGSVGAPGLRG 943
            GP G +GPPG KG++G  G PG          G  G PG  G  G  G PG  GAPG+ G
Sbjct: 814  GPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPG 873

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPG---LPG 999
             PG  GE G  G  G+ GSPGPVG  G PG  G  G PG  G  G+PGL+G  G   LPG
Sbjct: 874  FPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPG 933

Query: 1000 PLGT--KAACGKVRGS-----ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGP 1052
              G+  K   G ++G      E   +G    KG RG PG PG PG  G      AG PG 
Sbjct: 934  KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ-----AGQPGQ 988

Query: 1053 SGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG-LSSLLSPGDINLLAK 1111
             GP GD G  G+ G PG PGP+G  G  G PG PGE+G PG PG   S   PGD    AK
Sbjct: 989  PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKG--AK 1046

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171
                   P   G+PGL G KGD+G+ G PG  G +G+KG  G PG+PG PG+ G  GS G
Sbjct: 1047 GEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106

Query: 1172 ERGADGEVGQKGDQGHPG---VPGFMGPPGNPGPPGADGIAGAAGPPG---IQGSPGKEG 1225
              G+ G  G+KGD+G PG   +PG  G  G PG PG  G AG  G PG   I GS G++G
Sbjct: 1107 YPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKG 1166

Query: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSG 1285
             PG  G  G PG PG +G +G  G+ G PG  G  G PG  G +G  GPPG +G  G  G
Sbjct: 1167 EPGLPG-RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPG 1225

Query: 1286 APG-----PRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE--- 1337
            +PG     P+G+ G  G PG  GLPG  G  G  G  G +G +G PG  G+PG PG    
Sbjct: 1226 SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGD 1285

Query: 1338 ------PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPG------EPGEKGVPGKEGVPGK 1385
                  PG  G+PG  GSKG+ G PG+PGF GP+G PG      + G++GVPG +G+PG 
Sbjct: 1286 PGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGP 1345

Query: 1386 PG----------EPGFKGERGDPGIKGDKGPPGGKGQ---------PGDPGIPG------ 1420
            PG          EPG  G  G PG+KG +G PG KGQ         PG PGIPG      
Sbjct: 1346 PGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPG 1405

Query: 1421 ---HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 1454
                 G  G  GP+G PG  GP G PG  G PG P +
Sbjct: 1406 QKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442



 Score =  689 bits (1778), Expect = 0.0
 Identities = 437/1025 (42%), Positives = 506/1025 (49%), Gaps = 140/1025 (13%)

Query: 693  GLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPP 752
            G++G+KG+ G PG+ G++G       PG+ GP GP G PG  G+ G PG PG  G  GPP
Sbjct: 43   GVKGQKGERGLPGLQGVIGF------PGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPP 96

Query: 753  GKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 812
            G    +G PG PG  G PG+ G  G PG PG  G  GE+G  G PG  G AG PG PG P
Sbjct: 97   GA---SGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLP 153

Query: 813  GVRGEKGD----------QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 862
            G++G+ G+          +GE+G  G+PG  G  G  G  GP GPPG       FT  P 
Sbjct: 154  GMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPG-------FTGPPG 206

Query: 863  MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ-----EGAHGAPGAAGN 917
             PG  GP GEKG  GL      QG  G+ G QG +GPPG  GQ     +G     G  G 
Sbjct: 207  PPGPPGPPGEKGQMGL----SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQ 262

Query: 918  PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG------PVGPRGD 971
             G PG  G PG  G  G  G PG RG PGKDG++GEKG+ G  G PG        GP+G+
Sbjct: 263  KGEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGE 321

Query: 972  PGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDR 1027
             G  G PGPPG     G  GE G RG PG PGP G     G           G  V G  
Sbjct: 322  KGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQA 381

Query: 1028 GAPGIPGSPGSRGD---PGIGVAGPPGPSGPPGDKGSPGSRGLPGF-----------PGP 1073
            GAPG PG  G +GD   PG  + GP G  G PG  GSPG  G PG+           PG 
Sbjct: 382  GAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGD 441

Query: 1074 QGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 1133
            QGP G  G PG  GE G  G+ G S L+   DI+          PPG  G PG PG KGD
Sbjct: 442  QGPPGIPGQPGFIGEIGEKGQKGESCLIC--DIDGYRGPPGPQGPPGEIGFPGQPGAKGD 499

Query: 1134 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGS-------QGERGADGEVGQKGDQG 1186
            +G+PG   R+G  G  G  G PGL G PG  G  G        +G++G  G  GQ G  G
Sbjct: 500  RGLPG---RDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTG 556

Query: 1187 HPGVPGFMGPPGNPGP---PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL--PGIPGE 1241
              G PG  G PG PGP   PG+ G+ G  GPPG  G PG  G  GP GP G    G  G+
Sbjct: 557  RAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGD 616

Query: 1242 EGKEGRDGKPGPPGEPGKAGEPG----LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297
            +G+ G  G PG PG PG  GEPG    LPGP GA G PG        G PGP+G+ G  G
Sbjct: 617  KGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPG------SPGFPGPQGDRGFPG 670

Query: 1298 LPGQEGLPGKDGDTGPTG-----PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGE 1352
             PG+ GLPG+ G  G  G     P GP+G  G PG  G PG+PG PG +G PG  G +G+
Sbjct: 671  TPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQ 730

Query: 1353 NGSPG--LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
             G PG  LPG  G  G PG PG  G  G  GVPG PGE G  G  G  GI+G+ GPPG  
Sbjct: 731  KGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLP 790

Query: 1411 GQPGDPGIPG--HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLI 1468
            G  G PG+PG    G  G  G QG PG +GP G  G  G PGFPGL    P         
Sbjct: 791  GSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPK-------- 842

Query: 1469 QEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG---------LPGRAGPMGE 1519
                G +    L  +  Q     +   QG PG PG PG  G          PG  GP+G 
Sbjct: 843  ----GDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA 898

Query: 1520 PGRPGQGGLEGPSGPIGPKGERGAKGD------PGAPGV----------GLRGEMGPPGI 1563
            PG PG+ G  G  G  GP+G+ G KGD      PG PG           G +G+ G  G 
Sbjct: 899  PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ 958

Query: 1564 PGQPGEPGYAKD-GLPGIPGPQGETG------PAGHPGLPGPPGPPGQCDPSQCAYFASL 1616
             G  GE G   D G PG+PG  G+ G      P G PG+ G PG PG   P        L
Sbjct: 959  IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL 1018

Query: 1617 AARPG 1621
               PG
Sbjct: 1019 PGTPG 1023



 Score =  594 bits (1532), Expect = e-169
 Identities = 368/853 (43%), Positives = 439/853 (51%), Gaps = 93/853 (10%)

Query: 454  PPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPK 513
            P  P RP  PG +       I    P G KG  G+ G MG PG  G  G  G  G PG +
Sbjct: 669  PGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQ 728

Query: 514  GEKGDVGIG----------PFGQGEKGEKGSLGLPGPPGRDGS---KGMRGEPGELGEPG 560
            G+KG+ G+G          P   G  GEKGS+G+PG PG  G+    G++G  GE G PG
Sbjct: 729  GQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788

Query: 561  LPGEVGMRGPQG--PPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618
            LPG VG  G  G  PPG  GPPG  G PGL G  G KG +G  G  GLD  PG  GD G 
Sbjct: 789  LPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGA 847

Query: 619  QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARG 678
            QG PG +G +G  G  G  G  G PG PGS  +  G+ G  G PG  G  GAPG PG +G
Sbjct: 848  QGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEM-GVMGTPGQPGSPGPVGAPGLPGEKG 906

Query: 679  PIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIG 738
              G  G  GP G  GL+G KGD+G PG PG +          + G  G  G  G  G IG
Sbjct: 907  DHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMD---KVDMGSMKGQKGDQGEKGQIGPIG 963

Query: 739  FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG 798
              G  G PG  G PGKDG  G PG PG KG+PG  G  G PG PG +G +G  GL G PG
Sbjct: 964  EKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG 1023

Query: 799  EKGEAGLPGAPGFPGVRGEKGDQGEKGE-----LGLPGLKGDRG------------EKGE 841
            EKG  G+PG  G PG+ G+KG +GEKG+     +G+PGL+G++G            EKGE
Sbjct: 1024 EKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE 1083

Query: 842  AGPAGPPGLPGTTSL-----FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGP 896
             G  G PG+PG+  L        +P  PG  G KG+KG PGL G PG++G  G  G  GP
Sbjct: 1084 KGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGP 1143

Query: 897  TGPPGAKGQEGAHGAPGAAGNPGAPGHVGA--PGPSGPPGSVGAPGLRGTPGKDGERGEK 954
            TGP G KG+ G+ G PG+AG  G PG  G   PG  G  G  G+ G  G PG  G  G  
Sbjct: 1144 TGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIP 1203

Query: 955  GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014
            G+ GE+G  GP GP+G PG PG PG   +G  G+ G +G PGLPG  G     G      
Sbjct: 1204 GSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLP---- 1259

Query: 1015 NCALGGQCVKGDRGAPGIPGSPG---SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 1071
                G   VKGD+G PG PG+PG    +GDPG    G PG  G PG  GS G  G PG P
Sbjct: 1260 ----GIDGVKGDKGNPGWPGAPGVPGPKGDPGF--QGMPGIGGSPGITGSKGDMGPPGVP 1313

Query: 1072 GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGL------- 1124
            G QGP G  G  G  G++G  G PG   L  PG             PPGPPG        
Sbjct: 1314 GFQGPKGLPGLQGIKGDQGDQGVPGAKGL--PG-------------PPGPPGPYDIIKGE 1358

Query: 1125 PGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGD 1184
            PGLPG +G  G+ G  G  G +G++G  G  G+PGPPGI G  G+ G++G  G  G  G 
Sbjct: 1359 PGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGP 1418

Query: 1185 QGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG---------L 1235
            +G PG PG  G PG+ GPPG   +       G   +   +    PQ PSG         L
Sbjct: 1419 RGFPGPPGPDGLPGSMGPPGTPSV-----DHGFLVTRHSQTIDDPQCPSGTKILYHGYSL 1473

Query: 1236 PGIPGEEGKEGRD 1248
              + G E   G+D
Sbjct: 1474 LYVQGNERAHGQD 1486



 Score =  441 bits (1135), Expect = e-123
 Identities = 267/616 (43%), Positives = 316/616 (51%), Gaps = 86/616 (13%)

Query: 1037 GSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096
            G     G G     G  G  G++G PG +G+ GFPG QGP G  G PG  G+ G PG PG
Sbjct: 29   GGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG 88

Query: 1097 LSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 1156
                  P   +           PG PGLPG+PG  G  G PG PG  GT+G++G  GPPG
Sbjct: 89   TKGTRGPPGASGY---------PGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPG 139

Query: 1157 LPGPPGIAGPQGSQGERGADGEV-GQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 1215
            LPG  G  GP G  G +G  GE+ G        G  GF G PG PGPPG  G+ G  GPP
Sbjct: 140  LPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPP 199

Query: 1216 GIQGSPGKEGPPGPQGPSGLPGI--PGEEGKEGRDGKPGPPGEPGKA-----GEPGLPGP 1268
            G  G PG  GPPGP G  G  G+   G +G +G  G  GPPG PG+A     G+    G 
Sbjct: 200  GFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGE 259

Query: 1269 EGARGPPGFK-----GHTGDSGAPGPR---------GESGAMGLPGQEGLPGKDGDTGPT 1314
            +G +G PGF+     G  G+ G PGPR         GE G+ G PG+ G PG  G  GP 
Sbjct: 260  KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQ 319

Query: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK 1374
            G +G  GP GPPG     G  GE G  G PG  G +GE G  G PG  G  GPPG P   
Sbjct: 320  GEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP--- 376

Query: 1375 GVPGKEGVPGKPGEPGFKGERGDPG--IKGDKGPPGGKGQPGDPGIPGHKGHT-GLMGPQ 1431
             VPG+ G PG PGE G KG+RG PG  + G  G  G  G PG PG PG  G+T G++  Q
Sbjct: 377  -VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435

Query: 1432 GLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY 1491
              PG  G  GPPG PGQPGF G  GE               G++ E+ L           
Sbjct: 436  --PGPPGDQGPPGIPGQPGFIGEIGEK--------------GQKGESCLI--------CD 471

Query: 1492 MKSSQGRPGPPGPPGKDGLPGRAGPMGE---PGRPGQGGLEGPSGPIGPKGERGAKGDPG 1548
            +   +G PGP GPPG+ G PG+ G  G+   PGR G  G+ GP G  G  G+ GAKG+PG
Sbjct: 472  IDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG 531

Query: 1549 A--PGVGLRGEMGPPGIPGQPGEPGYA----KDGLPGIPGP---------QGETGPAGHP 1593
                 + L+G+ G PG PGQPG  G A    +DG PG+PGP         +GE GP G  
Sbjct: 532  EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591

Query: 1594 GLP------GPPGPPG 1603
            G P      GPPGPPG
Sbjct: 592  GFPGSRGDTGPPGPPG 607



 Score =  397 bits (1020), Expect = e-110
 Identities = 238/574 (41%), Positives = 287/574 (50%), Gaps = 94/574 (16%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            +P  P P   P  PG +              G+ G  G +GP G PG KGD G +G  G 
Sbjct: 889  QPGSPGPVGAPGLPGEK--------------GDHGFPGSSGPRGDPGLKGDKGDVGLPGK 934

Query: 510  PGP---------KGEKGDVG----IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL 556
            PG          KG+KGD G    IGP G  EKG +G  G PG PG+DG  G  G+PG  
Sbjct: 935  PGSMDKVDMGSMKGQKGDQGEKGQIGPIG--EKGSRGDPGTPGVPGKDGQAGQPGQPGPK 992

Query: 557  GEPGL---PGEVGMRGPQGP---------------PGLPGPPGRVGAPGLQGERGEKGT- 597
            G+PG+   PG  G+ GP+G                PG+PGP G  G PG +G +GEKG  
Sbjct: 993  GDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQA 1052

Query: 598  ----------RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG 647
                      RGEKG++G+ GFPG PG+ G++G  G  G+ G  G KG  G  G PG PG
Sbjct: 1053 GPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPG 1112

Query: 648  SVVQQ--EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP----------------- 688
               ++  +GL G  G PG +G  G PG PG  GP G +G  G                  
Sbjct: 1113 LPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPG 1172

Query: 689  ------PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP-- 740
                  PG +G +G KG++G PG+ G  G+ G  G  G  GPPGP G PGLPG  G    
Sbjct: 1173 RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATE 1232

Query: 741  ---GKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 797
               G  GP G  G PG  GP GPPG PG  G  G++G  G PG PG+ G  G+ G  G P
Sbjct: 1233 GPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMP 1292

Query: 798  GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGP---AGPPGLPGTT 854
            G  G  G+ G+ G  G  G  G QG KG  GL G+KGD+G++G  G     GPPG PG  
Sbjct: 1293 GIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPY 1352

Query: 855  SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA 914
             +    P +PG +GP G KG  GLPG  G QG  G +G  GP G PG  G  G  G  G 
Sbjct: 1353 DIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGP 1412

Query: 915  AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKD 948
            AG  G  G  G PGP G PGS+G P   GTP  D
Sbjct: 1413 AGPTGPRGFPGPPGPDGLPGSMGPP---GTPSVD 1443



 Score =  268 bits (684), Expect = 4e-71
 Identities = 161/367 (43%), Positives = 186/367 (50%), Gaps = 49/367 (13%)

Query: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337
            KG    SG  G     G  G  G+ GLPG  G  G  G QGP+GP+GPPG+ G  G PG 
Sbjct: 28   KGGCAGSGC-GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGL 86

Query: 1338 PGPSGTPGQKGSKGENGSPGLPGFLG---PRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 1394
            PG  GT G  G+ G  G+PGLPG  G   P GPPG PG  G  G+ G  G PG PGF G 
Sbjct: 87   PGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGN 146

Query: 1395 RGDPGIKGDKGPPGG-------------KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
             G PG+ G KG PG              +G PG PG PG  G  GL GP G PG  GP G
Sbjct: 147  PGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPG 206

Query: 1442 PPGPPGQPGFPGLRG---ESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGR 1498
            PPGPPG PG  G  G   + P  +   + +    G   +       AQ+      +++G 
Sbjct: 207  PPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQ-------AQVQEKGDFATKGE 259

Query: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV------ 1552
             G  G PG  G+PG  G  GEPG+PG  G  G  G  G KG  G  G+PG PG+      
Sbjct: 260  KGQKGEPGFQGMPG-VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP 318

Query: 1553 -GLRGEMGPPGIPG---------QPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPP 1602
             G +GE GPPG PG         + GE GY     PG PGP+GE GP G PGLPG PGPP
Sbjct: 319  QGEKGEAGPPGPPGIVIGTGPLGEKGERGY-----PGTPGPRGEPGPKGFPGLPGQPGPP 373

Query: 1603 GQCDPSQ 1609
            G   P Q
Sbjct: 374  GLPVPGQ 380



 Score =  200 bits (508), Expect = 1e-50
 Identities = 134/336 (39%), Positives = 149/336 (44%), Gaps = 65/336 (19%)

Query: 1328 KNGSPGSPGEPGPSGTPGQKGSKGENGSPGL------PGFLGPRGPPGEPGEKGVPGKEG 1381
            K G  GS    G     G KG KGE G PGL      PG  GP GP G PG+KG  G+ G
Sbjct: 28   KGGCAGSGC--GKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPG 85

Query: 1382 VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVG 1441
            +PG  G  G  G  G PG  G  G PG  G PG PGIPG  G  G  GP G PG  G  G
Sbjct: 86   LPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAG 145

Query: 1442 PPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGP 1501
             PGPPG PG  G  GE                         +L  +P   +K  +G PG 
Sbjct: 146  NPGPPGLPGMKGDPGE-------------------------ILGHVPGMLLKGERGFPGI 180

Query: 1502 PGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG-----------PKGERGAKGDPGAP 1550
            PG PG  GLPG  GP+G PG  G  G  GP GP G           PKG++G +G  G P
Sbjct: 181  PGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPP 240

Query: 1551 GV------------GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQG---------ETGP 1589
            GV              +GE G  G PG  G PG  + G PG PGP+G         E G 
Sbjct: 241  GVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGS 300

Query: 1590 AGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
             G PG PG PG  G+  P      A     PG V G
Sbjct: 301  PGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIG 336


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  890 bits (2300), Expect = 0.0
 Identities = 539/1249 (43%), Positives = 611/1249 (48%), Gaps = 187/1249 (14%)

Query: 423  IYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPPT-------------------- 462
            I CD +  +     +IP G C       P PP  P RPP                     
Sbjct: 65   IICDDQELDCPNP-EIPFGECCAVC---PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRN 120

Query: 463  --------PGSEQIGFLKTINCSCPAGE------------KGEMGVAGPMGLPGPKGDIG 502
                    PGS        I  SCP G             K  + V G  G PGP G  G
Sbjct: 121  GDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPG 180

Query: 503  AIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL 561
              GP G  G  G  G  G  GP   GE G+ G  G PGPPG  G  G  G+ GE G PG 
Sbjct: 181  PPGPPGTSGHPGSPGSPGYQGP--PGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGR 238

Query: 562  PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGR 621
            PGE   RG  GPPG+ GP G  G PG++G RG  G  GEKGE G  G  G+ G  G+ G 
Sbjct: 239  PGE---RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGA 295

Query: 622  PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIG 681
            PGP G  G  GE+G  G  G  G  G+   + G  G+ G PGP G  G PG PGA+G +G
Sbjct: 296  PGPMGPRGAPGERGRPGLPGAAGARGNDGAR-GSDGQPGPPGPPGTAGFPGSPGAKGEVG 354

Query: 682  PEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG------PGGSPGLPG 735
            P G  G  G  G RG+      PG  G  G QGPPGPPG+ G PG      P G PG PG
Sbjct: 355  PAGSPGSNGAPGQRGE------PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408

Query: 736  EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAG 795
             +G  G PGP G  G PG  G  G PG  G KGEPG RGE G  G PG+ G  GE G  G
Sbjct: 409  LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468

Query: 796  RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTS 855
             PGE G  GLPGA G    RG  G +G  G  G+PG KG  GE+G  GPAGP G  G   
Sbjct: 469  SPGEPGANGLPGAAG---ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525

Query: 856  LFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAA 915
                 P  PG +G  G  G PG  G+PG  G  GE G  GP GP G +GQ G  G PG  
Sbjct: 526  R-DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK 584

Query: 916  GNPGAPGH------VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG----------- 958
            GN GAPG        G PGP GPPG  G  G +G PG  G  G+KG  G           
Sbjct: 585  GNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP 644

Query: 959  -------EEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011
                   E G PG  GP+GD GAPG PG  GKG  G PG RG PGL G  G +   G   
Sbjct: 645  GTGGPPGENGKPGEPGPKGDAGAPGAPG--GKGDAGAPGERGPPGLAGAPGLRGGAGPP- 701

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGF 1070
            G E    GG+   G  G PG  G+PG +G PG  G  G PGP G  G+ G PG+ G+PG 
Sbjct: 702  GPE----GGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757

Query: 1071 PGPQGPAGRDGAPG---NPGERGPPGKPGLSSLL----SPGDINLLAKDVCNDCPPGPPG 1123
             GP+GP G  G PG    PG++G  G PGL  +     SPG+            PPGP G
Sbjct: 758  DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG-------PPGPAG 810

Query: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 1183
             PG PG  G+   PG  G  G  G+KGE GPPG+ GPPG +GP G  G +G  GE   +G
Sbjct: 811  FPGAPGQNGE---PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE---RG 864

Query: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243
              G PG  GF G  G PGPPG++G     GPPG  GSPGK+GPPGP G +G PG PG  G
Sbjct: 865  SPGGPGAAGFPGARGLPGPPGSNG---NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSG 921

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303
             +G  G+PG  G PG  G PG PGP G  G  G +G  G  G PGPRG  G  G+ G+ G
Sbjct: 922  PKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESG 981

Query: 1304 LPGKDGDTGPTGPQGPQ------GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357
             PG +G +G  GP GPQ      G  G PG++G+PGS G PG  G+PG KG +GENGSPG
Sbjct: 982  KPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPG 1041

Query: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417
             PG  G  GPPG  G  G  G  G  G  G  G  G  G  G  G +GP G KG+ G+ G
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101

Query: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 1477
              G KGH G  G  G PG  GP G  G  G PG  G RG                     
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP-------------------- 1141

Query: 1478 TRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGP 1537
                                  GP GPPGKDG  G  GP+            GP GP G 
Sbjct: 1142 ---------------------VGPSGPPGKDGTSGHPGPI------------GPPGPRGN 1168

Query: 1538 KGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGE 1586
            +GERG++G PG P     G+ GPPG PG PG P     G   I G  GE
Sbjct: 1169 RGERGSEGSPGHP-----GQPGPPGPPGAPG-PCCGGVGAAAIAGIGGE 1211



 Score =  811 bits (2096), Expect = 0.0
 Identities = 487/1057 (46%), Positives = 541/1057 (51%), Gaps = 139/1057 (13%)

Query: 624  PSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA--RGPIG 681
            P    GPQG KGD    GPPG+PG         G+ G PG  G  G+PGPPG     P G
Sbjct: 98   PPNGQGPQGPKGD---PGPPGIPGR-------NGDPGIPGQPGSPGSPGPPGICESCPTG 147

Query: 682  PEGR-------DGPPGLQ--GLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732
            P+         D   G+   GL G  G  GPPG PG  G  G PG PG PG  GP G PG
Sbjct: 148  PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPG 207

Query: 733  LPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE---RGEDGLPGKPGLRGEIG 789
              G  G PG PG  GP+GP GKDG +G PG PG +G PG    +G  G+PG PG++G  G
Sbjct: 208  QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267

Query: 790  ------EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE---KG 840
                  E+G  G PG KGE GLPG  G PG  G +G  GE+G  GLPG  G RG    +G
Sbjct: 268  FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327

Query: 841  EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP 900
              G  GPPG PGT   F   P   GE GP G  G  G PG+ G  G  G  G QGP GPP
Sbjct: 328  SDGQPGPPGPPGTAG-FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPP 386

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
            G  G  G  G  G AG PGAPG +GA GP GP G+ GAPGLRG  G+ G+ G KG     
Sbjct: 387  GINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG----- 441

Query: 961  GSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRG--SENCA 1017
              PGP G RG+ G PG+PG  G+ GKDG PG  G+ GLPG  G + A G  RG    N  
Sbjct: 442  -EPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG-FRGPAGPNGI 499

Query: 1018 LGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 1076
             G +   G+RGAPG  G  G+ G+PG  GV G PG  G PG  G PGS G PG PG QG 
Sbjct: 500  PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGE 559

Query: 1077 AGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 1136
            +GR G PG  G RG PG  G                      PGP G  G PG  G++G 
Sbjct: 560  SGRPGPPGPSGPRGQPGVMGF---------------------PGPKGNDGAPGKNGERGG 598

Query: 1137 PGKPGREGTEGKKGEAGPPGLPGPPGIAG---------PQGSQG---------ERGADGE 1178
            PG PG +G  GK GE GP G PGP G  G         PQG QG         E G  GE
Sbjct: 599  PGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGE 658

Query: 1179 VGQKGDQGHPGVPGFMGP---PGNPGPPG---ADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232
             G KGD G PG PG  G    PG  GPPG   A G+ G AGPPG +G  G  GPPGP G 
Sbjct: 659  PGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGA 718

Query: 1233 SGLPGIPGEEGKEGRDGKPGPPG---EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 1289
            +G PG+ G  G+ G  G PGP G   EPG  G  G+PG +G RGP G  G  G +G PG 
Sbjct: 719  AGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGD 778

Query: 1290 RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG---------SPGSPGEPGP 1340
            +GE GA GLPG  G  G  G+ G TGP GP G  G PG+NG         +PG  GE GP
Sbjct: 779  KGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGP 838

Query: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE---PGFKGERGD 1397
             G  G  G  G  G PG  G  G RG PG PG  G PG  G+PG PG    PG  G  G 
Sbjct: 839  PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898

Query: 1398 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 1457
            PG  G  GP G  G PG PG+ G KG  G  G +G PG  GP G PGP G  G  G RG 
Sbjct: 899  PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958

Query: 1458 S--PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG------PPGKDG 1509
            +  P M   R                       P  +K   G+PG  G      PPG  G
Sbjct: 959  AGPPGMPGPR-------------------GSPGPQGVKGESGKPGANGLSGERGPPGPQG 999

Query: 1510 LPGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1566
            LPG AG  GEPGR   PG  GL G  G  G KG+RG  G PGAPG    G  GPPG  G 
Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA--PGHPGPPGPVGP 1057

Query: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
             G+ G    G  G  GP G  GPAG  G PGP GP G
Sbjct: 1058 AGKSG--DRGESGPAGPAGAPGPAGSRGAPGPQGPRG 1092



 Score =  764 bits (1974), Expect = 0.0
 Identities = 460/1030 (44%), Positives = 518/1030 (50%), Gaps = 131/1030 (12%)

Query: 657  GEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPP 716
            GE  A  P+       PP  +GP GP+G  GPPG+ G  G       PGIPG  G  G P
Sbjct: 82   GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGD------PGIPGQPGSPGSP 135

Query: 717  GPPGV--PGPPGPGG-SP-----------GLPGEIGFPGKPGPPGPTGPPGKDGPNGPPG 762
            GPPG+    P GP   SP            + G  G+PG  GPPGP GPPG  G  G PG
Sbjct: 136  GPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG 195

Query: 763  PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG 822
             PG +G PGE G+ G  G PG  G IG  G AG+ GE G  G PG  G PG  G KG  G
Sbjct: 196  SPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAG 255

Query: 823  EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEP 882
              G  G+ G +G  G  GE G  G PGL G   L       PGE G  G  G  G PGE 
Sbjct: 256  IPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGL-------PGENGAPGPMGPRGAPGER 308

Query: 883  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942
            G  G PG  G +G  G  G+ GQ G  G PG AG PG+PG  G  GP+G PGS GAPG R
Sbjct: 309  GRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQR 368

Query: 943  GTPGKDGERGEKGAAGE---EGSPG---PVGPRGDPGAPGLPG---PPGK-GKDGEPGLR 992
            G PG  G  G +G  G     GSPG    +GP G PGAPGL G   PPG  G +G PGLR
Sbjct: 369  GEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR 428

Query: 993  GSPGLPGPLGTKAACGKVRGSENCA--LGGQCVKGDRGAPGIPGSPGSRGDPGI------ 1044
            G  G PG  G K   G  RG    A   G    KG+ G  G PG PG+ G PG       
Sbjct: 429  GGAGEPGKNGAKGEPGP-RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487

Query: 1045 -GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPGNPGERGPPGKPG-LSS 1099
             G  GP GP+G PG+KG  G RG PG  GP+G AG   RDG PG PG RG PG PG   S
Sbjct: 488  PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 1100 LLSPGDINLLAKDVCNDCPPGP------PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAG 1153
               PG      +      PPGP      PG+ G PG KG+ G PGK G  G  G  G  G
Sbjct: 548  DGKPGPPGSQGESG-RPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606

Query: 1154 PPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
            PPG  G  G  GP G  G  G  G+ G  G QG  G+PG  GPPG  G PG  G  G AG
Sbjct: 607  PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273
             PG  G  G  G PG +GP GL G PG  G  G    PGP G  G AG PG PG  G  G
Sbjct: 667  APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAG---PPGPEGGKGAAGPPGPPGAAGTPG 723

Query: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPG---KNG 1330
              G  G  G  G+PGP+G+ G  G PG +G+PGKDG  GPTGP GP GP G PG   + G
Sbjct: 724  LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG 783

Query: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG--- 1387
            +PG PG  GP G+PG++G  G  G  G PG  G  G PG  GE+G PG++G  G PG   
Sbjct: 784  APGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAG 843

Query: 1388 EPGFKGERGDPG---IKGDKGPPGGKGQPGDPGI------PGHKGHTGLMGPQGLPGENG 1438
             PG  G  G PG   +KG++G PGG G  G PG       PG  G+ G  GP G PG++G
Sbjct: 844  PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903

Query: 1439 PVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGR 1498
            P GP G  G PG PG+ G                                    K   G+
Sbjct: 904  PPGPAGNTGAPGSPGVSGP-----------------------------------KGDAGQ 928

Query: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE---RGAKGDPGAPGV-GL 1554
            PG  G PG  G PG  GP+G  G  G  GL GP G  GP+G    +G KG+ G PG  GL
Sbjct: 929  PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988

Query: 1555 RGEMGPPGIPGQPG------EPGY----------AKDGLPGIPGPQGETGPAGHPGLPGP 1598
             GE GPPG  G PG      EPG            +DG PG  G +GE G  G PG PG 
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048

Query: 1599 PGPPGQCDPS 1608
            PGPPG   P+
Sbjct: 1049 PGPPGPVGPA 1058



 Score =  469 bits (1208), Expect = e-132
 Identities = 291/666 (43%), Positives = 321/666 (48%), Gaps = 105/666 (15%)

Query: 452  PPPPPPQRPP-TPGSEQIGFLKTINCSCPA--GEKGEMGVAGPMGLPGPKGDIGAIGPVG 508
            P PP P  P   PG       K  N   P   GE+G  G  GP G PG  G+ G  GP G
Sbjct: 563  PGPPGPSGPRGQPGVMGFPGPKG-NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG 621

Query: 509  APGPKGEKGDVGI-GPFGQ-------GEKGEKGSLGLPGP------PGRDGSKGMRGEPG 554
              GP G+KGD G  GP G        G  GE G  G PGP      PG  G KG  G PG
Sbjct: 622  PTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPG 681

Query: 555  ELGEPGLPGEVGMRGPQGPPGL---------PGPPGRVGAPGLQGERGEKG------TRG 599
            E G PGL G  G+RG  GPPG          PGPPG  G PGLQG  GE+G       +G
Sbjct: 682  ERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKG 741

Query: 600  EKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQ 659
            +KGE G  G  G PG  G +G  GP G  GP G+ GD G  G PG+PG       + G +
Sbjct: 742  DKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG-------IAGPR 794

Query: 660  GAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPP 719
            G+PG RG  G PGP G  G  G  G  G  G +G  G+KG+ GPPG+ G  G  GP GPP
Sbjct: 795  GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPP 854

Query: 720  GVPGPPGPGGSPGLPGEIGFPG------------KPGPPGPTGPPGKDGPNGPPGPPGTK 767
            G  G  G  GSPG PG  GFPG             PGPPGP+G PGKDGP GP G  G  
Sbjct: 855  GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 768  GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA------PGFPGVRGEKGDQ 821
            G PG  G  G  G+PG +G  G QG  G PG  G AG+ GA      PG PG RG  G Q
Sbjct: 915  GSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQ 974

Query: 822  GEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL-----FTPHPRMPGEQGPKGEKGDP 876
            G KGE G PG  G  GE+G  GP G PGL GT              +PG  G  G KGD 
Sbjct: 975  GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034

Query: 877  GLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG-- 934
            G  G PG  G PG  GP GP GP G  G  G  G  G AG PG  G  GAPGP GP G  
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094

Query: 935  -------SVGAPGLRGTPGKDGERGEKGAAGEEG---SPGPVGPRGDPGAPGLPG----- 979
                   + G  G RG PG  G  G  G AG++G   SPGP GPRG  G  G PG     
Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTS 1154

Query: 980  -------PPGK-------------GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALG 1019
                   PPG              G  G+PG  G PG PGP      CG V  +    +G
Sbjct: 1155 GHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP-----CCGGVGAAAIAGIG 1209

Query: 1020 GQCVKG 1025
            G+   G
Sbjct: 1210 GEKAGG 1215



 Score =  144 bits (363), Expect = 7e-34
 Identities = 108/317 (34%), Positives = 124/317 (39%), Gaps = 100/317 (31%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIG------- 505
            PP P      PGS  +   K    +   GEKG  G  GP G PGP G  G  G       
Sbjct: 904  PPGPAGNTGAPGSPGVSGPK--GDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP 961

Query: 506  -----PVGAPGPKGEKGDVGI-------------GPFG-------QGEKGEKGSLGLPGP 540
                 P G+PGP+G KG+ G              GP G        GE G  G+ G  G 
Sbjct: 962  PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL 1021

Query: 541  PGRDGSKGMRGEPGELGEPGLPG------------------EVGMRGPQGPPGLPGPPGR 582
            PGRDGS G +G+ GE G PG PG                  + G  GP GP G PGP G 
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 583  VGAPGLQGERGEKGTRGEKGERGLDGF---------PGKPGDTGQQG------------- 620
             GAPG QG RG+KG  GE+G  G+ G          PG PG  GQQG             
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141

Query: 621  --------------RPGPSGVAGPQGEKGD------------VGPAGPPGVPGSVVQQEG 654
                           PGP G  GP+G +G+             GP GPPG PG      G
Sbjct: 1142 VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVG 1201

Query: 655  LKGEQGAPGPRGHQGAP 671
                 G  G +    AP
Sbjct: 1202 AAAIAGIGGEKAGGFAP 1218



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 61/143 (42%), Positives = 67/143 (46%), Gaps = 10/143 (6%)

Query: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG-----PIGPKGERGA 1543
            P    + QG  GP G PG  G+PGR G  G PG+PG  G  GP G     P GP+     
Sbjct: 95   PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQ 154

Query: 1544 KGD----PGAPGVGLRGEMGPPGIPGQPGEPGYA-KDGLPGIPGPQGETGPAGHPGLPGP 1598
                    G    GL G  GP G PG PG PG +   G PG PG QG  G  G  G  GP
Sbjct: 155  YDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGP 214

Query: 1599 PGPPGQCDPSQCAYFASLAARPG 1621
            PGPPG   PS  A     + RPG
Sbjct: 215  PGPPGAIGPSGPAGKDGESGRPG 237


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  883 bits (2281), Expect = 0.0
 Identities = 540/1248 (43%), Positives = 613/1248 (49%), Gaps = 239/1248 (19%)

Query: 478  CPAGEKGEMGVAGPMGLPGPKGDI-GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLG 536
            CP       G  GP G  G  GDI   +GP G PGP+G  G+ G     +G++G+KG  G
Sbjct: 89   CPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG----PRGDRGDKGEKG 144

Query: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVG------------------------MRGPQG 572
             PGP GRDG  G  G PG  G PG PG  G                        M+GP G
Sbjct: 145  APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 573  PPGLPGPPGRVGAPGLQ------GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSG 626
            P G  GPPG  GAPG Q      GE GE G  G  G RG  G PGKPGD G+ G+PG +G
Sbjct: 205  PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 264

Query: 627  VAGPQGEKGDVGPAGPPGVPGSVVQQ-----EGLKGEQGAPGPRGHQGAPGPPGARGPIG 681
              GP G +G  G  G PG+PG    +     +G KGE GAPG +G  G+PG  G+ GP+G
Sbjct: 265  ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 324

Query: 682  PEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPG 741
            P         +GL G++G  GP G  G  G  G PGP G PGP GP G PG PG  G  G
Sbjct: 325  P---------RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKG 375

Query: 742  KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP---- 797
            + GP G  GP G  GP G PG PG+ G  G  G  G  G PG +G  G  G+AG P    
Sbjct: 376  EAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPG 435

Query: 798  --------------GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP------GLKGDRG 837
                          G KG+ G PG  GF G +G KG+ G  G  G P      G +G RG
Sbjct: 436  PRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARG 495

Query: 838  EKGEAGPAGPP---------GLPGTTSLFTPHPRMPGEQ------GPKGEKGDPGLPGEP 882
            E G  GP GPP         G PG   L  P    PGE+      GPKG  GDPG PGEP
Sbjct: 496  EPGGVGPIGPPGERGAPGNRGFPGQDGLAGP-KGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 883  ------GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP---SGPP 933
                  GL GRPG+ GPQG  GP GA G++G  G PG  G  G PG +G PGP   +G P
Sbjct: 555  GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614

Query: 934  GSV------GAPGLRGTPGKDGER------GEKGAAGEEGSPGPVGPRGDPGAPGLPGPP 981
            G        GAPGLRG PGKDGE       G  G AGE G  G  GP G  G PG PGPP
Sbjct: 615  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 982  GK----GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037
            G+    G  G PG  G+PGL GP G +   G+ RGS     G Q ++G RG PG PG+ G
Sbjct: 675  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE-RGSP----GAQGLQGPRGLPGTPGTDG 729

Query: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097
             +G    G AGPPG  GPPG +G PG RG  G  GP+G        G+ GE+GP G PG 
Sbjct: 730  PKG--ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDR------GDVGEKGPEGAPG- 780

Query: 1098 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157
                  G   L         P GPPG  G  G KG+ G PG  G  G  G  GE G  G 
Sbjct: 781  ----KDGGRGLTG-------PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 1158 PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP----------------- 1200
            PGP G AGP G+ G+ GA GE G+ G +G  G PG  GP G P                 
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889

Query: 1201 -GPPGADGIAGAA---GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP---GP 1253
             GPPGA G  GAA   GPPG  G+PG  GPPGP G  G  G  G+ G  GR G+P   GP
Sbjct: 890  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949

Query: 1254 PGEPGKAGEPGLPGPEGARGPP---GFKGHTGDSGAPGPRGESGAMGL------PGQEGL 1304
             G PG+ GEPG  GP GA GPP   G  G  G  G PG RGE G  GL      PG++G 
Sbjct: 950  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 1305 PGKDGDTGPTGPQGP---QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361
            PG  GD GP GP GP    GP G PG+ GSPG+ G PG  G  G KG +GE G+ G PG 
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069

Query: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH 1421
             GP G PG  G  G  G  G  G  G  G  G  G  GI+G +GP G KG+ G+PG  G 
Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL 1129

Query: 1422 KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLA 1481
            KGH G  G QGLP      GPPGP G  G  G                            
Sbjct: 1130 KGHRGFTGLQGLP------GPPGPSGDQGASG---------------------------- 1155

Query: 1482 YLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
                   PA     +G PGP GP GKDG  G  GP+G PG  G+ G  GP+GP       
Sbjct: 1156 -------PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP------- 1201

Query: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGP 1589
                 PG P        GPPG PG PG PG       G+ GP+ E GP
Sbjct: 1202 -----PGNP--------GPPGPPGPPG-PGIDMSAFAGL-GPR-EKGP 1233



 Score =  867 bits (2240), Expect = 0.0
 Identities = 526/1203 (43%), Positives = 603/1203 (50%), Gaps = 194/1203 (16%)

Query: 551  GEPGELGEPGLPGEV-GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF 609
            G+PG  G+ G PG++  + GP+GPPG  GP G  G  G +G++GEKG  G +G  G  G 
Sbjct: 98   GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 610  PGKPGDTGQQGRPGPSGVAGP---------------------QGEKGDVGPAGPPGVPGS 648
            PG PG  G  G PGP G+ G                      QG  G +GP GPPG    
Sbjct: 158  PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG---- 213

Query: 649  VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPG 708
                       GAPGP+G QG PG PG  G  GP G  GPPG  G   K GD G  G PG
Sbjct: 214  ---------PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG---KPGDDGEAGKPG 261

Query: 709  LLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPG------KPGPPGPTGPPGKDGPNGPPG 762
              G +GPPGP G  G PG  G PG+ G  G+PG      + G PG  G  G  G NG PG
Sbjct: 262  KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG 321

Query: 763  PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG 822
            P G +G PGERG  G  G  G RG  G+ G AG PG  G AG PG PG PG +GE G  G
Sbjct: 322  PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTG 381

Query: 823  EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE- 881
             +G  G  G +G+ G  G  GPAG  G PGT  +    P   G  G  G  G PG PG  
Sbjct: 382  ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI----PGAKGSAGAPGIAGAPGFPGPR 437

Query: 882  --PGLQGRPGELGPQGPTGPPGA---KGQEGAHGAPGAAGNPGAPGHVGAPG-------- 928
              PG QG  G LGP+G TG PG    KG++G  G PG AG  GAPG  G  G        
Sbjct: 438  GPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEP 497

Query: 929  ----PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRG---DPGAPGLPGPP 981
                P GPPG  GAPG RG PG+DG  G KGA GE G  G  GP+G   DPG PG PG P
Sbjct: 498  GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557

Query: 982  GK----------------GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025
            G                 G  G PG  G PG PGP G +   G +         G+   G
Sbjct: 558  GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE--PG 615

Query: 1026 DRGAPGIPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081
              G  G+PG+PG RG PG     G AGPPGP+GP G++G  G+ G  GF G  GP G  G
Sbjct: 616  KAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675

Query: 1082 APGNPGERGPPGKPGLSSLLSP-GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 1140
              G PG++G PG+ G   L+ P G+             PG  G PG  G +G +G+PG P
Sbjct: 676  EGGKPGDQGVPGEAGAPGLVGPRGERGF----------PGERGSPGAQGLQGPRGLPGTP 725

Query: 1141 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200
            G +G +G  G AGPPG  GPPG+   QG  GERGA G  G KGD+G  G  G  G PG  
Sbjct: 726  GTDGPKGASGPAGPPGAQGPPGL---QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKD 782

Query: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260
            G  G  G  G  GP G  G  G+ GPPGP G +G  G PGE G+ G      PPG  G A
Sbjct: 783  GGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG------PPGPAGFA 836

Query: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA------MGLPGQEGLPGKDGDTGPT 1314
            G PG  G  GA+G  G  G  GD+GAPGP+G SGA       G+ G +G  G  G  G T
Sbjct: 837  GPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGAT 896

Query: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---PGFLGPRGPPGEP 1371
            G  G  G  GPPG NG+PG PG PGPSG  G KG++G++G PG    PG  GP GPPGE 
Sbjct: 897  GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956

Query: 1372 GEKGVPGKEGVPGKPGE------------PGFKGERGDPGIKGDKGPPGGKGQP---GDP 1416
            GE G  G  G  G PG             PG +GERG PG+ G  G PG +G P   GD 
Sbjct: 957  GEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDR 1016

Query: 1417 GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 1476
            G PG  G  GL GP G PG  G  G  GPPG+ G  G++G+           + E G   
Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD-----------RGETG--- 1062

Query: 1477 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA---GPMGEPGRPGQGGLEGPSG 1533
               +    A  PP       G PGP GP GK G  G A   GPMG  G  G  G++GP G
Sbjct: 1063 --AVGAPGAPGPP-------GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1113

Query: 1534 PIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYA---------------- 1573
            P G KGE G  G+ G  G     GL+G  GPPG  G  G  G A                
Sbjct: 1114 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173

Query: 1574 KDGLPGIPGP---------QGETGPAGHPGLPGPPGPPGQCDPS-QCAYFASLAARPGNV 1623
            KDG  GIPGP          GETGPAG PG PGPPGPPG   P    + FA L  R    
Sbjct: 1174 KDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE--- 1230

Query: 1624 KGP 1626
            KGP
Sbjct: 1231 KGP 1233



 Score =  742 bits (1916), Expect = 0.0
 Identities = 432/931 (46%), Positives = 487/931 (52%), Gaps = 75/931 (8%)

Query: 480  AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFG-QGEKGEKGSLGL 537
            AG +G  G  GP G PGP G  G  G  GAPG KGE G  G  GP G QG +GE G+ G 
Sbjct: 341  AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 400

Query: 538  PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT 597
            PGP G  G+ G  G PG  G  G PG  G  G  GP G PGP G  G  G +G+ GE G 
Sbjct: 401  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 598  RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ-----Q 652
             G KGE+G  G PG  G  G  G  G  G  G +GE G VGP GPPG  G+        Q
Sbjct: 461  AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 520

Query: 653  EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGL 712
            +GL G +GAPG RG  G  GP GA G  G  G  G PG +GL G+ GD GP G    +G 
Sbjct: 521  DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG---KVGP 577

Query: 713  QGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             G PG  G PGPPGP G+ G PG +GFPG   P G  G PGK G  G PG PG +G PG+
Sbjct: 578  SGAPGEDGRPGPPGPQGARGQPGVMGFPG---PKGANGEPGKAGEKGLPGAPGLRGLPGK 634

Query: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
             GE G  G PG  G  GE+G  G PG  G  GLPG PG PG  G+ GDQG  GE G PGL
Sbjct: 635  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694

Query: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGD---PGLPGEPGLQGR 887
             G RGE+G  G  G PG  G   L  P   P  PG  GPKG  G    PG  G PGLQG 
Sbjct: 695  VGPRGERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 751

Query: 888  PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947
            PGE G  G  GP G +G  G  G  GA G  G  G  G  GP GP G+ G  G  G PG 
Sbjct: 752  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 811

Query: 948  DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAA 1006
             G  G +GA GE G  GP GP G  G PG  G PG KG+ GE G +G  G PGP G   A
Sbjct: 812  AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 871

Query: 1007 CGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSR 1065
             G          G   V G +GA G  G PG+ G PG  G  GPPG +G PG  G PG  
Sbjct: 872  PGPQ--------GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923

Query: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125
            G  G  G +G +G  G  G PG +GP G PG      PGD      +     PPGP GL 
Sbjct: 924  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--EPGDDGPSGAEG----PPGPQGLA 977

Query: 1126 G------LPGFKGDKGVPG------KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173
            G      LPG +G++G PG      +PG++G  G  G+ GPPG  GPPG+ GP G  G  
Sbjct: 978  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 1037

Query: 1174 GA---------DGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224
            G+         DG  G KGD+G  G    +G PG PGPPG+ G AG  G  G +G  G +
Sbjct: 1038 GSPGADGPPGRDGAAGVKGDRGETGA---VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1094

Query: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284
            GP GP GP+G  GI G +G  G  G+ G PGE G  G  G  G +G  GPP   G +GD 
Sbjct: 1095 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP---GPSGDQ 1151

Query: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344
            GA GP G SG  G PG  G  GKDG  G  GP GP GPRG  G+ G  G PG PGP G P
Sbjct: 1152 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1211

Query: 1345 GQKGSKGENGSPGLP----GFLGPRGPPGEP 1371
            G  G       PG+       LGPR    +P
Sbjct: 1212 GPPG-------PGIDMSAFAGLGPREKGPDP 1235



 Score =  673 bits (1737), Expect = 0.0
 Identities = 413/991 (41%), Positives = 471/991 (47%), Gaps = 175/991 (17%)

Query: 748  PTGPPGKDGPNGPPGPPGTKGEP-------------------------GERGEDGLPGKP 782
            P  P      +G PGP G KGEP                         G+RG+ G  G P
Sbjct: 87   PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146

Query: 783  GLRGEIGEQGLAGRPGEKGEAGLPGAPGF------------------------------- 811
            G RG  GE G  G PG  G  G PG PG                                
Sbjct: 147  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 206

Query: 812  -----------PGVRGEKGDQGEKGELGL---------------PGLKGDRGEKGEAGPA 845
                       PG +G +G+ GE GE G+               PG  G+ G+ G+AG  
Sbjct: 207  GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 266

Query: 846  GPP------GLPGTTSL--FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPT 897
            GPP      G PGT  L     H   PG  G KGE G PG+ GE G  G  G  GP GP 
Sbjct: 267  GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 326

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP---PGSVGAPGLRGTPGKDGERGEK 954
            G PG +G+ G  GA GA GN G PG  G PGP GP   PG  GAPG +G  G  G RG +
Sbjct: 327  GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 955  GAAGEE------GSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACG 1008
            GA G        GSPGP G  G+PG  G+PG   KG  G PG+ G+PG PGP G     G
Sbjct: 387  GAQGPRGEPGTPGSPGPAGASGNPGTDGIPG--AKGSAGAPGIAGAPGFPGPRGPPGPQG 444

Query: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGL 1067
                    A G    KG  G PGI G  G +G  G  G AGP G  GP G++G  G+RG 
Sbjct: 445  --------ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 496

Query: 1068 PGFPGPQGPAGRDGAPGN---------PGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP 1118
            PG  GP GP G  GAPGN          G +G PG+ G S L  P   N           
Sbjct: 497  PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGAN----------- 545

Query: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178
             G PG PG PG  G +G+ G+PG  G +GK G +G PG  G PG  GPQG++G+ G  G 
Sbjct: 546  -GDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 1179 VGQKGDQGHPGVPGFMGPPGNP---GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL 1235
             G KG  G PG  G  G PG P   G PG DG  GAAGPPG  G  G+ G  G  GPSG 
Sbjct: 605  PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 1236 PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA 1295
             G+PG  G  G  GKPG  G PG+AG PGL GP G RG PG +G  G  G  GPR   G 
Sbjct: 665  QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPR---GL 721

Query: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355
             G PG +G  G  G  GP G QGP G +G PG+ G+ G  G  G  G  G+KG +G  G 
Sbjct: 722  PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK 781

Query: 1356 PGLPGFLGPRGPP------GEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 1409
             G  G  GP GPP      GE GE G PG  G  G  G PG +GE G PG  G  GPPG 
Sbjct: 782  DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 841

Query: 1410 KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQ 1469
             GQ   PG  G +G  G  G  G PG  GP G PGP G  G  G +G   +         
Sbjct: 842  DGQ---PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ-------- 890

Query: 1470 EELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLE 1529
               G    T       ++ P     + G PGPPGP GKDG  G  G  G PGR G+ GL+
Sbjct: 891  ---GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947

Query: 1530 GPSGPIGPKGE------RGAKGDPGAPGV----------GLRGEMGPPGIPGQPGEPGYA 1573
            GP+GP G KGE       GA+G PG  G+          G RGE G PG+PG  GEPG  
Sbjct: 948  GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG-- 1005

Query: 1574 KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604
            K G PG  G +G  GP G PGL GP G PG+
Sbjct: 1006 KQGAPGASGDRGPPGPVGPPGLTGPAGEPGR 1036



 Score =  407 bits (1047), Expect = e-113
 Identities = 248/603 (41%), Positives = 291/603 (48%), Gaps = 120/603 (19%)

Query: 1112 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171
            + C  CP       G PG KG KG PG       +   G  GPPG  GP G  GP+G +G
Sbjct: 84   ECCPICPTDLATASGQPGPKGQKGEPG-----DIKDIVGPKGPPGPQGPAGEQGPRGDRG 138

Query: 1172 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI----------------------- 1208
            ++G  G  G +G  G PG PG  GPPG PGPPG  G+                       
Sbjct: 139  DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 1209 ----------------AGAAGPPGIQGSPGK------EGPPGPQGPSGLPGIPGEEGKEG 1246
                            AGA GP G QG+PG+       GP GP+GP G PG PG++G+ G
Sbjct: 199  MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 1247 RDGK------PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA----- 1295
            + GK      PGP G  G  G PGLPG +G RG PG  G  G++GAPG +GESG+     
Sbjct: 259  KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318

Query: 1296 -------MGLPGQE---------GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339
                    GLPG+          G  G DG  GP GP GP GP G PG  G+PG+ GE G
Sbjct: 319  SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 378

Query: 1340 PSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE---GVPGKPGEPGFKGERG 1396
            P+G  G +G++G  G PG PG  GP G  G PG  G+PG +   G PG  G PGF G RG
Sbjct: 379  PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGH------KGHTGLMGPQGLP------------GENG 1438
             PG +G  GP G KGQ G+PGI G       KG  G  GPQG P            GE G
Sbjct: 439  PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 1439 PVGPPGPPGQPGFPGLRG----------------ESPSMETLRRLIQEELGKQLETRLAY 1482
             VGP GPPG+ G PG RG                  PS     +    + G+  E  L  
Sbjct: 499  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 1483 LLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERG 1542
                         QG+ GP G PG+DG PG  GP G  G+PG  G  GP G  G  G+ G
Sbjct: 559  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAG 618

Query: 1543 AKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGP 1601
             KG PGAPG+ GL G+ G  G  G PG  G A     G  G QG  GP+G  GLPGPPGP
Sbjct: 619  EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPA-----GERGEQGAPGPSGFQGLPGPPGP 673

Query: 1602 PGQ 1604
            PG+
Sbjct: 674  PGE 676



 Score =  145 bits (365), Expect = 4e-34
 Identities = 92/242 (38%), Positives = 109/242 (45%), Gaps = 20/242 (8%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPP----TPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGL 494
            P GP     +T P   P  +  P     PG +    +K        G++GE G  G  G 
Sbjct: 1018 PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK--------GDRGETGAVGAPGA 1069

Query: 495  PGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPG 554
            PGP G  G  GP G  G +GE G  G      G  G  G+ G+ GP G  G KG  GEPG
Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQG----PMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1125

Query: 555  ELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPG 614
            E G  G  G  G++G  GPPG  G  G  G  G  G RG  G  G  G+ G +G PG  G
Sbjct: 1126 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1185

Query: 615  DTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP----RGHQGA 670
              G +GR G +G AGP G  G  GP GPPG    +    GL   +  P P    R  Q A
Sbjct: 1186 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1245

Query: 671  PG 672
             G
Sbjct: 1246 GG 1247


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  881 bits (2276), Expect = 0.0
 Identities = 565/1302 (43%), Positives = 646/1302 (49%), Gaps = 242/1302 (18%)

Query: 476  CSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSL 535
            C C   EKG  G  GP G  GP G +GA GP+G  G KG +GD G  P   G+KG+KG  
Sbjct: 55   CHC-VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG-PPGAAGDKGDKGPT 112

Query: 536  GLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPP---GLPGPPGRVGAPGLQGER 592
            G+PG PG DG  G  G PG  G+PG+ G  G RG  G P   G  GP G +G PG +GE+
Sbjct: 113  GVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEK 172

Query: 593  GE--------KGTRGEKGERGLDGFPGK---PGDTGQQGRPGPSGVAGPQGEKGDVGPAG 641
            G         KG +G++G+ GL G PG     G  G  G PG  G+ GP G+ G  G  G
Sbjct: 173  GNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKG 232

Query: 642  PPGV--------PGSVVQQEG--------------LKGEQGAPGPRGHQGAPGPPGARGP 679
             PGV        PG V QQ                 KGE+G  G  G  G PGPPG +G 
Sbjct: 233  NPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGE 292

Query: 680  --IGPEGRDGPPGLQGLRGKKGDMGPPGIPGL---LGLQGPPGPPGVPGP---PGPGGSP 731
              IG +G  G PG  G RG  G  G PG PGL   LGL G PG  G+ GP   PG  G P
Sbjct: 293  SGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHP 352

Query: 732  GLPGEIGFPGKP--GPPGPTGPPGKDGPN---GPPGPPGTKGEPGER--------GEDGL 778
            G PG +  P  P  GPPG  G PG+ G     GPPGPPG  G PGE         G  G 
Sbjct: 353  GPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGF 412

Query: 779  PGKPGLRGEIGEQG----LAGRPGEKGEAGLPGAPGFPGVRGEK---------GDQGEKG 825
            PG PGL GE G  G      G+PG+ G  GLPGAPG  G+ G           G QG KG
Sbjct: 413  PGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKG 472

Query: 826  ELGLPGLKGDRGEKG-------EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 878
            ++G PG +G +GEKG       E GP GPPG PG          +PG Q   G KGD GL
Sbjct: 473  KVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPG----------LPGRQ---GSKGDLGL 519

Query: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG------APGHVGAPGPSGP 932
            PG  G +G P   GP G  GPPG  G+ GA G PG  G  G        GH G  GP GP
Sbjct: 520  PGWLGTKGDP---GPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGP 576

Query: 933  PGSVGAPGLRGTPGKDGERGEKGAAGE--------EGSPGPVGPRGDPGAPGLPGPPGKG 984
            PG  G PG  G  G  GE+G+ G  G+        +G PGP+GP   PG  G  GPPG G
Sbjct: 577  PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGP---PGKAGPVGPPGLG 633

Query: 985  KDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI 1044
              G PG RG PG+PG  G       VRG +   L GQ  KGD  +  +   PG  G PG 
Sbjct: 634  FPGPPGERGHPGVPGHPG-------VRGPD--GLKGQ--KGDTISCNVT-YPGRHGPPGF 681

Query: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104
               GPPGP G PG +G+PG  G  G  G  G  G    PG PG RG  G PG        
Sbjct: 682  D--GPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGG----- 734

Query: 1105 DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP--GREGTEGKKGEAGPPGLPGP-- 1160
                         P GPPG PG PG  G KG+PG P  G  G  GK+G +G PG+ GP  
Sbjct: 735  --------EKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRG 786

Query: 1161 -PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN---------PGPPGADGIAG 1210
             PG  G +G  G  G  G  G KG +GH G PG  GPPG+         PG PG  G  G
Sbjct: 787  DPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPG 846

Query: 1211 AAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEG 1270
            + G PG +G PG  GPPGP G  GLPG+PG  G  G  G PG PG  G  G PG PGP+G
Sbjct: 847  SPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKG 906

Query: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP-------- 1322
             RG PGF G  G+ G PG  G  GA G PG++G+ G  GD G  G +G  GP        
Sbjct: 907  PRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMA 966

Query: 1323 ----RGPPGKNGSPGS---PGEPGPSGTPGQKGSKGENGSPGLPGF----------LGPR 1365
                +G PG+ G PG    PGE G  GTPG +G +GE G  G PGF           GP 
Sbjct: 967  IISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPP 1026

Query: 1366 GPPGEPGE---------KGVPGKEGVPGKPGEPGFKGERGDPGIKGDK-------GPPGG 1409
            GPPG PG           G+PG +G PG PG PGF G  G  G KG+K       GPPG 
Sbjct: 1027 GPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGP 1086

Query: 1410 KGQPGDPGIPGH------KGHTGLMGPQGLPGENGP---VGPPGPPGQPGFPGLRGESPS 1460
            KG+PG PG PGH      +G  G+ GP+G PG  GP    GPPG PG  G PGLRG+   
Sbjct: 1087 KGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGE 1146

Query: 1461 METLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPP---GPPGKDGLPGRAGPM 1517
            M                           P  ++   G PGPP   GP G  GL G  G  
Sbjct: 1147 M-----------------------GDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLK 1183

Query: 1518 GEPGRPGQGGLE--GPSGPIGPKGERGAKGDPGAPGV---GLRGEMGPPGIPGQPGEPGY 1572
            G+ G  G  GL   GP GP+G  G +G +GDPG+PG+   G RG+ GPPG PG  G PG 
Sbjct: 1184 GQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGP 1243

Query: 1573 A-------KD-GLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606
            A       KD   PG PG QG  GP G  G PGPPG PG  D
Sbjct: 1244 AGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVD 1285



 Score =  861 bits (2224), Expect = 0.0
 Identities = 580/1435 (40%), Positives = 671/1435 (46%), Gaps = 323/1435 (22%)

Query: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAP 510
            PP PP PQ P  P          +    P G  GE G+ G  G PG  GD G  GP G P
Sbjct: 66   PPGPPGPQGPIGP----------LGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVP 115

Query: 511  G------------PKGEKGDVGIG-----------PFGQGEKGEKGSLGLPGPPGRDGS- 546
            G            P G +G  G+            P G+G  G  G LG PG  G  G+ 
Sbjct: 116  GFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNS 175

Query: 547  -------KGMRGEPGELGEPGLPGEVGMRGPQGP------PGLPGPPGRVGAPGLQGE-- 591
                   KG++G+ G+ G PGLPG  G  GP GP      PGL GPPG+ G PGL+G   
Sbjct: 176  VFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPG 235

Query: 592  ---RGEKGTRGE---------------------KGERGLDGFPGKPGDTGQQGRPGPSGV 627
               +G+ G  GE                     KGE+G+ G PG  G  G  GR G SG+
Sbjct: 236  VGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGI 295

Query: 628  AGPQGEKGDVGPAGPPGVPGS--------------VVQQEGLKGEQGAPGPRGHQGAPGP 673
             G +GEKG  G  GP G PGS              +V   GL G  G  G  G++G PGP
Sbjct: 296  -GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGP 354

Query: 674  PGA--RGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG--------LQGPPGPPGVPG 723
            PG     P+  +G  G PG  G  G+ GD+GPPG PGLLG        + GPPGP G PG
Sbjct: 355  PGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPG 414

Query: 724  PPG----------PGGSPGLPGEIGFPGKPGPPG------------PTGPPGKDGPNGPP 761
             PG          P  +PG PG+ G PG PG PG              G PG  G  G  
Sbjct: 415  LPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKV 474

Query: 762  GPPGTKGEPGERGEDGLPG-KPGLRGEIGEQGLAGRPGEKGEAGLPG------APGFPGV 814
            GPPG +G  GE+G +GL   +PG  G  G  GL GR G KG+ GLPG       PG PG 
Sbjct: 475  GPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGA 534

Query: 815  RGEKGDQGEKGELGLPGLKGDRGE---------KGEAGPAGPPGLPGTTSLFTPHPRMPG 865
             G  G  G+ G  G PG KG +G+         KGE GP GPPG PG        P   G
Sbjct: 535  EGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG-------QPGSHG 587

Query: 866  EQGPKGEKGDPGLPGE-----PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGA 920
              G  GEKGDPG PG+     PG +G PG LGP G  GP G  G  G  G PG  G+PG 
Sbjct: 588  RDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGV 646

Query: 921  PGHVGAPGPSGPPGSVGA--------PGLRGTPGKDGERGEKGAAGEEGSPGPVGP---R 969
            PGH G  GP G  G  G         PG  G PG DG  G KG  G +G+PG  G    +
Sbjct: 647  PGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHK 706

Query: 970  GDPGAPG---LPGPPG-KGKDGEPGLRGSPGL-----PGPLGTKAACGKVRGSENCALGG 1020
            G PG PG   +PGPPG +G  G+PG  G  G      PGP G+    G+     + A G 
Sbjct: 707  GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH 766

Query: 1021 QCVKGDRGAPGIPGSPGSRGDPGI----------------------------GVAGPPGP 1052
                G RG  G+PG  G RGDPG                             GV GPPG 
Sbjct: 767  LGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH 826

Query: 1053 S---------------GPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097
            S               G PG  G+PG +G PG  GP GPAG  G PG PG  G  G PGL
Sbjct: 827  SCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGL 886

Query: 1098 SSLLSP-GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 1156
              +  P GD  L         P GP GLPG PGF G++G PG  G  G +G+ GE G  G
Sbjct: 887  PGIPGPFGDDGLPGPPG----PKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSG 942

Query: 1157 LPGPPGIAGPQGSQGERGADGE---VGQKGDQGHPGVPGFMGPPGN------PGPPGADG 1207
            LPG  G+ G +G+ G  G +GE   + QKG  G PG PG  G PG       PG  G  G
Sbjct: 943  LPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRG 1002

Query: 1208 IAGAAGPPGI-QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266
              G  GPPG  +G PG++G PGP GP G PG  G  G  G  G PG  GEPG  G PG  
Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFS 1062

Query: 1267 GPEGARGPPGFKGHTGDS-GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGP 1325
            G +GARGP G KG      G PGP+GE G+ G PG  G  G+ G  G  GP+G  G  GP
Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP 1122

Query: 1326 PGKNGSPGSPGE---------PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 1376
            PG +G PG PG+         PG  G PG +G +G+ G PG PG  GP G PG  G  G+
Sbjct: 1123 PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGL 1182

Query: 1377 PGKEGV-----------PGKPGEPGFKGERGDPGIKG--DKGPPGGKGQPGDPGIPGHKG 1423
             G++G            PG  G PG KGERGDPG  G    GP G KG PG PG  G  G
Sbjct: 1183 KGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPG 1242

Query: 1424 HTGLMG-------PQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 1476
              G  G         G PG+ GP GP GP G PG PGL G   S++ LR           
Sbjct: 1243 PAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPG---SVDLLR----------- 1288

Query: 1477 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPG---------KDG------LPGRAGPMGEPG 1521
                     +     +    G PGPPGPPG         KDG       PG  GP G PG
Sbjct: 1289 --------GEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG 1340

Query: 1522 RPGQGGLEGPSGPIGPKGERGAKGDPG----------------APGV-GLRGEMGPPGI- 1563
             PG+ GL GP G  GP G  G +G+PG                APG+ G  G MG PG+ 
Sbjct: 1341 PPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMR 1400

Query: 1564 ----PGQPGEPGY----AKDGLPGIPGP---QGETGPAGHPGLPGPPGPPGQCDP 1607
                PG  GEPG       DG+PG PGP   +G+TG  G+PG PGPPGP G   P
Sbjct: 1401 GPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGP 1455



 Score =  830 bits (2145), Expect = 0.0
 Identities = 531/1298 (40%), Positives = 617/1298 (47%), Gaps = 226/1298 (17%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP--------------- 497
            PP  P RP   G+  +G           G+ G+ G  G  G PGP               
Sbjct: 221  PPGQPGRPGLKGNPGVGV---------KGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGE 271

Query: 498  KGDIGAIGPVGAPGPKGEKGDVGIGPFGQ-------GEKGEKGSLGLPGPPGRDGSKGMR 550
            KG  G  G VG PGP G KG+ GIG  G+       G +G+ GS G PG PG  G  G+ 
Sbjct: 272  KGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLV 331

Query: 551  GEPGELGEPGLPGEVGMRGPQGPPG--------LPGPPGRVGAPGLQGERGEKGTRGEKG 602
            G+PG  G  G  G+ G RG  GPPG        L GPPG  G PG  GE G+ G  G  G
Sbjct: 332  GDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPG 391

Query: 603  E--------RGLDGFPGKPGDTGQQGRPGPSGVAG-PQGEKGDVGPAGPPGVPGSVVQQE 653
                      G+ G PG  G  G  G PG +G+ G P    G  G  G PG+PG+   Q 
Sbjct: 392  LLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQ- 450

Query: 654  GLKGEQ------GAPGPRGHQGAPGPPGARGPIGPEGRDG----------PPGLQGLRGK 697
            GL G        G PGP+G +G  GPPG RGP G +G +G          PPG  GL G+
Sbjct: 451  GLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGR 510

Query: 698  KGDMGPPGIPGLLGLQGPPGPPGVPGPPG---------PGGSPGLPGEI------GFPGK 742
            +G  G  G+PG LG +G PGPPG  GPPG         P G+ G  G++      G  G+
Sbjct: 511  QGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGE 570

Query: 743  PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERG--EDGLPGKPGLRGEIGEQGLAGR---- 796
             GP GP G PG+ G +G  G  G KG+PG  G  ED  PG  G  G +G  G AG     
Sbjct: 571  RGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPP 630

Query: 797  ----PGEKGEAGLPGAPGFPGVRGEKGDQGEKGEL-----------GLPGLKGDRGEKGE 841
                PG  GE G PG PG PGVRG  G +G+KG+            G PG  G  G KG 
Sbjct: 631  GLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGF 690

Query: 842  AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901
             GP G PGL G+      H   PG  G     G PG  G+ G  G  GE G   P GPPG
Sbjct: 691  PGPQGAPGLSGSDG----HKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKG-SSPVGPPG 745

Query: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961
              G  G +G  G  G+P A GH+G PG  G  G  G  G RG PG  G  G  G  G  G
Sbjct: 746  PPGSPGVNGQKGIPGDP-AFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLG 804

Query: 962  SPGPVGPRGDPGAPGLPGPPGKGKD-GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGG 1020
              GP G  G  G PG+PGPPG   + G PG+ G PGLPG  G+  A G  +G     +G 
Sbjct: 805  LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGG-KGQPG-DVGP 862

Query: 1021 QCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR 1079
                G +G PG+PG PG+ G PG+ G+ GP G  G PG  G  G RGLPGFPG  G  G+
Sbjct: 863  PGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGK 922

Query: 1080 DGAPGNPGERGPPGKPGLSSLLS-------------PGDINLLAKDVCNDCP--PGPPGL 1124
             GA G PG +G PG+ G+S L               PGD   +A       P  PGPPG 
Sbjct: 923  PGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGD 982

Query: 1125 PGLPGFKGDKGVPGKPGREGTEGK-------KGEAGPPGLPGPPGIAGPQGSQGERGADG 1177
             G PG +GDKG PG  GR G  G+       +GE G  G PGPPG  GP GS G RG  G
Sbjct: 983  DGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIG 1042

Query: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE-GPPGPQGPSGLP 1236
                      PG+PG  G PG+PGPPG  GI GA GP G +G P    GPPGP+G  G P
Sbjct: 1043 ---------FPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093

Query: 1237 GIPGEEGKEGRDGKPG---PPGEPGKAGEPGLPGPEGA---RGPPGFKGHTGDSGAPGPR 1290
            G PG  G  G  G PG   P G PG+ G PG  GP G     G PG +G  G+ G PGPR
Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR 1153

Query: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG-----------PPGKNGSPGSPGEPG 1339
            G  G  G+PG  G+ G  G  G  G  G +G +G           PPG  G PG  GE G
Sbjct: 1154 GLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERG 1213

Query: 1340 PSGTPG--QKGSKGENGSPGLPGFLGPRGP-------------PGEPGEKGVPGKEGVPG 1384
              G+PG    G +G+ G PG PG  GP GP             PG PG++G PG +G  G
Sbjct: 1214 DPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRG 1273

Query: 1385 KPGEPGF-------KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN 1437
             PG PG        +GE GD G+ G  GPPG  G PG  G PG  G  G  GP G PG  
Sbjct: 1274 APGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQ 1333

Query: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497
            GP G PGPPG+ G PG  G                                P  +   +G
Sbjct: 1334 GPHGFPGPPGEKGLPGPPGRKG-----------------------------PTGLPGPRG 1364

Query: 1498 RPGPPGP-------PGKDGLPGRAGPMGEPGRPGQGGLEGPS--GPIGPKGERGAKGDPG 1548
             PGPP         PG  G PG  GP G  G PG  G  GP   G  G  G RG  G PG
Sbjct: 1365 EPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPG 1424

Query: 1549 APGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQG 1585
            +PG  G +G+ G  G PG PG PG   D     PGP+G
Sbjct: 1425 SPGPPGRKGDTGEDGYPGGPGPPGPIGD-----PGPKG 1457



 Score =  774 bits (1999), Expect = 0.0
 Identities = 503/1175 (42%), Positives = 572/1175 (48%), Gaps = 193/1175 (16%)

Query: 564  EVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPG 623
            E G RGP GPPG  GP G +GAPG  G  GEKG RG++G       PG  GD G +G  G
Sbjct: 60   EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGP------PGAAGDKGDKGPTG 113

Query: 624  PSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPE 683
              G  G  G  G  GP GP G PG      G  G +G PG  G +GA GP G  G  G +
Sbjct: 114  VPGFPGLDGIPGHPGPPGPRGKPG----MSGHNGSRGDPGFPGGRGALGPGGPLGHPGEK 169

Query: 684  GRDGPP-----GLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIG 738
            G  G        ++G++G +GD G PG+PG  G  GP GP G PG PG  G PG PG  G
Sbjct: 170  GEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPG 229

Query: 739  FPGKPGP--PGPTGPPGKDGPNGPPGPP------------GTKGEPGERGEDGLPGKPGL 784
              G PG    G  G PG+ G  G PGP             G KG  G  G  GLPG PG 
Sbjct: 230  LKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGR 289

Query: 785  RGEIG-----EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEK 839
            +GE G     E+G+ G PG +G+ G  G+PGFPG++GE G  G+ G  GL G KGD G +
Sbjct: 290  KGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNR 349

Query: 840  GEAGPAG---PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGP 896
            G  GP G    P LP         P  PG  G  GE GD G PG PGL GRPGE    G 
Sbjct: 350  GHPGPPGVLVTPPLP-----LKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE-ACAGM 403

Query: 897  TGPPGAKGQEGAHGAPGAAGNPGAPGHV-GAPGPSGPPGSVGAPGLRGTPGKD------G 949
             GPPG +G  G  G PG AG PG P    G PG  G PG  GAPGL+G PG        G
Sbjct: 404  IGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVG 463

Query: 950  ERGEKGAAGEEGSPGPVGPRGDPG-------APGLPGPPGK-GKDGEPGLRGSPGLPGPL 1001
              G +G  G+ G PG  GP+G+ G        PG  GPPG  G  G  G +G  GLPG L
Sbjct: 464  NPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWL 523

Query: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPG 1057
            GTK   G   G+E    G   + G  GA G PG+ G++GD  +    G  G  GP GPPG
Sbjct: 524  GTKGDPGPP-GAE----GPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPG 578

Query: 1058 DKGSPGSRGLPGFPGPQGPAG-----RDGAPGN---PGERGPPGKPGLSSLLSPGDINLL 1109
              G PGS G  G  G +G  G      D  PG    PG  GPPGK G             
Sbjct: 579  FPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAG------------- 625

Query: 1110 AKDVCNDCPPGPPGL--PGLPGFKGDKGVPGKPGREGTEGKKGEAGP--------PGLPG 1159
                    P GPPGL  PG PG +G  GVPG PG  G +G KG+ G         PG  G
Sbjct: 626  --------PVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHG 677

Query: 1160 PPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQG 1219
            PPG  GP G +G  G  G  G  G  GH G PG  G    PGPPG  G  G  G  G +G
Sbjct: 678  PPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKG 737

Query: 1220 S-----PGKEGPPGPQGPSGLPGIP--GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272
            S     PG  G PG  G  G+PG P  G  G  G+ G  G PG  G  G+PG PG EG  
Sbjct: 738  SSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPA 797

Query: 1273 GPPGF---------KGHTGDSGAPGPRGES---GAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320
            G PGF         +GH G  G PGP G S   GA G+PGQ GLPG  G  G  G +G  
Sbjct: 798  GIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQP 857

Query: 1321 G---PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVP 1377
            G   P GP G  G PG PG PG  G PG  G  G  G  GLPG  GP+GP G PG  G P
Sbjct: 858  GDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFP 917

Query: 1378 GKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN 1437
            G+ G PG  G PG KGE G+ G+ G  G  G +G  G  G PG +G   ++  +G PGE 
Sbjct: 918  GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGE- 976

Query: 1438 GPVGPPGPPGQPGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY---- 1491
                 PGPPG  GFPG RG+  +P M+  R     E G+             PP +    
Sbjct: 977  -----PGPPGDDGFPGERGDKGTPGMQGRR----GEPGR-----------YGPPGFHRGE 1016

Query: 1492 --MKSSQGRPGPPGPPGKDGL------PGRAGPMGEPGRPGQGGLEGPSGPIGPKGER-- 1541
               K   G PGPPGPPG  GL      PG  G  GEPG PG  G  G  G  GPKG +  
Sbjct: 1017 PGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGD 1076

Query: 1542 --------GAKGDPGAPGV----------GLRGEMGPPGIPGQPGEPG----------YA 1573
                    G KG+PG+PG           GL G  GP G PG+PG PG          + 
Sbjct: 1077 PASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHG 1136

Query: 1574 KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608
              GL G PG  G+ GP G  G PG PGPPG   PS
Sbjct: 1137 MPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPS 1171



 Score =  774 bits (1999), Expect = 0.0
 Identities = 500/1184 (42%), Positives = 565/1184 (47%), Gaps = 212/1184 (17%)

Query: 479  PAGEKGEMGVA-----GPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG-------IGPFGQ 526
            P G KGE G+      G  G PGP+GD G+ G  G PG KGE G VG       IGP G 
Sbjct: 286  PPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGD 345

Query: 527  -GEKGEKGSLG--------LPGPPGRDGSKGMRGEPGELGEPGLPG-----------EVG 566
             G +G  G  G        L GPPG  G  G  GE G++G PG PG            +G
Sbjct: 346  PGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIG 405

Query: 567  MRGPQGPPGLPGPPGRVGAPG----LQGERGEKGTRGEKGERGLDGFPGK---------P 613
              GPQG PGLPG PG  G PG      G+ G+ G+ G  G  GL G PG          P
Sbjct: 406  PPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNP 465

Query: 614  GDTGQQGRPGPSGVAGPQGEKGD----------VGPAGPPGVPGSVVQQEGLKGEQGAPG 663
            G  G +G+ GP G  GP+GEKG+          +GP GPPG+PG    ++G KG+ G PG
Sbjct: 466  GPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG----RQGSKGDLGLPG 521

Query: 664  PRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPG 723
              G +G PGPPGA GP G  G+ G  G  G +G KGDM    + G  G +GP GPPG PG
Sbjct: 522  WLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG 581

Query: 724  PPGPGGSPGLPGEIGFPGKPGP-----------PGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             PG  G  G  GE G PG PG            PGP GPPGK GP GPPG  G  G PGE
Sbjct: 582  QPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGE 640

Query: 773  RGEDGLPGKPGLRG--------------------EIGEQGLAGRPGEKGEAGLPGAPGFP 812
            RG  G+PG PG+RG                      G  G  G PG KG  G  GAPG  
Sbjct: 641  RGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLS 700

Query: 813  GVRGEKGDQGEKGELGLPGLKGDRGEKGE-----------AGPAGPPGLPGTTS------ 855
            G  G KG  G  G   +PG  G RG+ G+            GP GPPG PG         
Sbjct: 701  GSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPG 760

Query: 856  ------LFTPHPR-MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTG---------- 898
                  L  P  R + G  G KG +GDPG PG  G  G PG LG +GP G          
Sbjct: 761  DPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGV 820

Query: 899  --PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAP------GLRGTPGKDGE 950
              PPG   + GA G PG  G PG PG  GAPG  G PG VG P      GL G PG+ G 
Sbjct: 821  PGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGA 880

Query: 951  RGEKGAAGEEGS---------PGPVGPRGDPGAPGLPGPPGK-------GKDGEPGLRGS 994
             G  G  G  G          PGP GPRG PG PG PG  GK       G  GEPG +G 
Sbjct: 881  HGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGM 940

Query: 995  PGLPGPLG---TKAACGKVRGSENCALGGQCVKGDRGAPGIPGS---PGSRGDPGI---- 1044
             GLPG  G    K A G        A+  Q  KG  G PG PG    PG RGD G     
Sbjct: 941  SGLPGDRGLRGAKGAIGPPGDEGEMAIISQ--KGTPGEPGPPGDDGFPGERGDKGTPGMQ 998

Query: 1045 GVAGPPGPSGPPG-DKGSPGSRGLPGFPGPQGPAGRDGA---------PGNPGERGPPGK 1094
            G  G PG  GPPG  +G PG +G PG PGP GP G  G          PG+ GE G PG 
Sbjct: 999  GRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGP 1058

Query: 1095 PGLSSLLSP-GDINLLAKDVCNDCPPGP---PGLPGLPGFKGDKGVPGKPGREGTEGKKG 1150
            PG S +    G          +  PPGP   PG PG PG  G  G  G PG +G  G  G
Sbjct: 1059 PGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPG 1118

Query: 1151 EAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 1210
              GPPG  GPPG  G  G  G RG  GE+G  G +G  G PG  GPPG  GP G+ G+ G
Sbjct: 1119 RPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNG 1178

Query: 1211 AAGPPGIQGSPGKEG--PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 1268
              G  G +G+ G  G    GP GP G+PG+ GE G  G  G   PPG  GK G PG PG 
Sbjct: 1179 LHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGI-SPPGPRGKKGPPGPPGS 1237

Query: 1269 EGARGPPGFKGHT----------GDSGAPGPRGESGAMGLPGQEG----LPGKDGDTGPT 1314
             G  GP G  G            GD G PGP G  GA G PG  G    L G+ GD G  
Sbjct: 1238 SGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP 1297

Query: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEK 1374
            GP GP GP GPPG  G PG  G+ G  G  G  G +G +G PG PG  G  GPPG  G  
Sbjct: 1298 GPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPT 1357

Query: 1375 GVPGKEG-------------VPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH 1421
            G+PG  G             +PG PG PG +G  G  G+ G +GP  G G  G+PG+ G 
Sbjct: 1358 GLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGP-SGPGCKGEPGLDGR 1416

Query: 1422 KGHTGLMGPQGLPG------ENGPVGPPGPPGQPGFPGLRGESP 1459
            +G  G+ G  G PG      E+G  G PGPPG  G PG +G  P
Sbjct: 1417 RGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGP 1460



 Score =  719 bits (1857), Expect = 0.0
 Identities = 461/1071 (43%), Positives = 527/1071 (49%), Gaps = 179/1071 (16%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            +P  P  P  P  PG + +     I CS              +G PGP+G  G +GP G 
Sbjct: 434  KPGKPGSPGLPGAPGLQGLPGSSVIYCS--------------VGNPGPQGIKGKVGPPGG 479

Query: 510  PGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRG 569
             GPKGEKG+ G+      E G  G  G PG PGR GSKG  G PG LG  G PG     G
Sbjct: 480  RGPKGEKGNEGLCAC---EPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGP---PG 533

Query: 570  PQGPPGLPGPPGRVGAPGLQGERGE------KGTRGEKGERGLDGFPGKPGDTGQQGRPG 623
             +GPPGLPG  G  G PG +G +G+      KG +GE+G  G  GFPG+PG  G+ G  G
Sbjct: 534  AEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAG 593

Query: 624  PSGVAGPQGE--------KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPG 675
              G  GP G+        KG  GP GPPG  G  V   GL G  G PG RGH G PG PG
Sbjct: 594  EKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGP-VGPPGL-GFPGPPGERGHPGVPGHPG 651

Query: 676  ARGPIGPE--------------GRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721
             RGP G +              GR GPPG  G  G KG  GP G PGL G  G  G PG 
Sbjct: 652  VRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGT 711

Query: 722  P-----------------------------GPPGPGGSPGLPGEIGFPGKP-----GPPG 747
            P                             GPPGP GSPG+ G+ G PG P     GPPG
Sbjct: 712  PGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPG 771

Query: 748  P---TGPPGKDGPNGPPGPPGT------------KGEPGERGEDGLPGKPGLRGEIGEQG 792
                +G PG  GP G PG PG             KG  G  G  G PG PG  G   E+G
Sbjct: 772  KRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERG 831

Query: 793  LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852
              G PG+ G  G PG+PG PG +G+ GD G  G  G+ GL G  G  G  GP G PG+PG
Sbjct: 832  APGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPG 891

Query: 853  TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK------GQE 906
                      +PG  GPKG +G PG PG PG +G+PG  G  G  G PG K      G  
Sbjct: 892  PFG----DDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947

Query: 907  GAHGAPGAAGNPGAPGHV------GAPGPSGPPGSVGAPGLR---GTPGKDGERGE---- 953
            G  GA GA G PG  G +      G PG  GPPG  G PG R   GTPG  G RGE    
Sbjct: 948  GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007

Query: 954  ------KGAAGEEGSPGPVGPRGDPGAPGLPG----PPGKGKDGEPGLRGSPGLPGPLGT 1003
                  +G  GE+G PGP GP G PG+ GL G    P   G  GEPG  G PG  G  G 
Sbjct: 1008 GPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGA 1067

Query: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----------GVAGPPGPS 1053
            +   G  +G      G    KG+ G+PG PG  G+ G+ G+          G  GPPG S
Sbjct: 1068 RGPKGN-KGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSS 1126

Query: 1054 GP---PGDKGSPGSRGLP---GFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS-PGDI 1106
            GP   PGD G PG RG P   G PGP+G  G  G PG PG +GP G PGL+ L    G  
Sbjct: 1127 GPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQK 1186

Query: 1107 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG--REGTEGKKGEAGPPGLPGPPGIA 1164
                    +D   GPPG  G+PG KG++G PG PG    G  GKKG  GPPG  GPP   
Sbjct: 1187 GTKGASGLHDV--GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPP--- 1241

Query: 1165 GPQGSQGERGAD-GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 1223
            GP G+ G    D  + G  GDQG PG  G  G PG PG PG+  +    G PG  G PG 
Sbjct: 1242 GPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDL--LRGEPGDCGLPGP 1299

Query: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGD 1283
             GPPGP GP G  G PG +GK   DG+ GP G PG  G  G PGP G +G PG  G  G 
Sbjct: 1300 PGPPGPPGPPGYKGFPGCDGK---DGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGP 1356

Query: 1284 SGAPGPRGESG----------AMGLPGQEGLPGKDGDTGPTGPQGPQGP--RGPPGKNGS 1331
            +G PGPRGE G            GLPG  G+ G +G  G  G +GP GP  +G PG +G 
Sbjct: 1357 TGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGR 1416

Query: 1332 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV-PGKEG 1381
             G  G PG  G PG+KG  GE+G PG P   GP GP G+PG KG  PG  G
Sbjct: 1417 RGVDGVPGSPGPPGRKGDTGEDGYPGGP---GPPGPIGDPGPKGFGPGYLG 1464


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  880 bits (2275), Expect = 0.0
 Identities = 526/1168 (45%), Positives = 599/1168 (51%), Gaps = 149/1168 (12%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG------IGPFGQGEKGEK 532
            PAG  G MG  G  G  GP GD G  GP G PG  G  G  G      + PF  G  G K
Sbjct: 458  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517

Query: 533  G-----------------SLGLPGPP------GRDGSKGMRGEPGELGEPGLPGEVGMRG 569
            G                  + L GPP      GR G  G  G  G  GE G PG  G RG
Sbjct: 518  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577

Query: 570  PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629
             QGPPG  G PG+ G PG  G RG  G  G KG+RG DG PG PGD G +G  GP G  G
Sbjct: 578  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 637

Query: 630  PQGE---KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD 686
            P G+   +G+ G  GP G+PG         G +G  GPRG  GAPG PG  G       D
Sbjct: 638  PPGDDGMRGEDGEIGPRGLPGEA-------GPRGLLGPRGTPGAPGQPGMAGV------D 684

Query: 687  GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP 746
            GPPG       KG+MGP G PG  G QG PGP G+PGP GP G PG  G  G PG  G P
Sbjct: 685  GPPG------PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP 738

Query: 747  GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 806
            G  GPPG  G  G  G  G  G PG +G  G PG  G++G  G +GL G  GEKGE G  
Sbjct: 739  GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 797

Query: 807  GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT----SLFTPH-P 861
              PGF G  G KGD+GE G++G  G  G  G KG AGP G PG  G       L  P  P
Sbjct: 798  --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855

Query: 862  RMPGEQGPKGEKGDPGLP------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP--- 912
              PG QGPKG  G PG P      G  G+ G+PG  G +GPTGP G++G  G  G P   
Sbjct: 856  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 915

Query: 913  GAAGNPGAPGHVGAPGPSGPPGSVGAPGLR---GTPGKD------GERGEKGAAGEEGSP 963
            G +G  G PG  G  GP GP G VG PG +   G PGKD      G+RGE G  G+ G P
Sbjct: 916  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 975

Query: 964  GP------------VGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKV 1010
            GP             GP G+ G PG PGPPG +G  G  G  G+ G PGP G     G  
Sbjct: 976  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1035

Query: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSR---GL 1067
                    G +   G+RG PG  G+PG +G  G G  GPPGP G PG++GS G+    GL
Sbjct: 1036 --------GLRGFPGERGLPGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGL 1085

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL 1127
            PG PGPQGP G  G  G PGE+GP G  G   +  P  +            PGP G  G 
Sbjct: 1086 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL------------PGPAGPAGS 1133

Query: 1128 PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            PG  GDKG  G+PG++G++G KGE GP   PGPPG+ GP G+ G  G DGE G +G QG 
Sbjct: 1134 PGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1190

Query: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR 1247
             G  G  G  G PGPPG  G+ G  GPPG +G  G  GP GP GP G  G  G  G +G 
Sbjct: 1191 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP 1250

Query: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
             G PG  G  G  GE G PG  G  GPP      G++G  GP+GE G  G  G  G  G 
Sbjct: 1251 QGPPGSVGSVGGVGEKGEPGEAGNPGPP------GEAGVGGPKGERGEKGEAGPPGAAGP 1304

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGP--- 1364
             G  GP G  GP+G  GP G  G PG PGEPGP+G  G  G KGE+G PG PG  GP   
Sbjct: 1305 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1364

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
             GPPG PG++G PG  G  G+ GE G KGE G  G  G  GP G +G  G PG  G +G 
Sbjct: 1365 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI 1424

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             G +G QGLPG  G  GPPGP G PG PGL+G+  S            G++    L  L+
Sbjct: 1425 PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-----------GEKGHPGLIGLI 1473

Query: 1485 AQMPPAYMKSSQGRP---GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
                    K  +G P   G PG  G  G+PG AGP+G PG PG  G +GP G  G  G  
Sbjct: 1474 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1533

Query: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569
            G KGD G P        GPPG PG PGE
Sbjct: 1534 GQKGDSGLP--------GPPGSPGPPGE 1553



 Score =  847 bits (2189), Expect = 0.0
 Identities = 519/1205 (43%), Positives = 596/1205 (49%), Gaps = 173/1205 (14%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM-------GLPGPKGDIG 502
            +P  PP  +  P   +E      +IN     GEKG+ G    +       G PGP G  G
Sbjct: 404  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 463

Query: 503  AIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGR----------DGSKG--- 548
             +GP G  GP G  GD G  GP   G  G  G+ GLPGPPG           DGSKG   
Sbjct: 464  IMGPPGLQGPTGPPGDPGDRGP--PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 521

Query: 549  -----------------MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591
                             +RG PG +G  G PG VG  G  G  G  G PG  G  G+QG 
Sbjct: 522  SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 581

Query: 592  RGEKGTRGEKGERGLDG---FPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
             G  G  G++G  G DG    PG+PG  G +G  G  G+ G +G +G+ GP GPPG PG 
Sbjct: 582  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 641

Query: 649  VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGK---KGDMGPPG 705
                +G++GE G  GPRG  G  GP G  GP G  G  G PG+ G+ G    KG+MGP G
Sbjct: 642  ----DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765
             PG  G QG PGP G+PGP GP G PG  G  G PG  G PG  GPPG  G  G  G  G
Sbjct: 698  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 757

Query: 766  TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825
              G PG +G  G PG  G++G  G +GL G  GEKGE G PG   F G  G KGD+GE G
Sbjct: 758  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG---FKGDMGLKGDRGEVG 814

Query: 826  ELGLPGLKGDRGEKGEAGPAGPPGLPGTTS----LFTPH-PRMPGEQGPKGEKGDPGLPG 880
            ++G  G  G  G KG AGP G PG  G       L  P  P  PG QGPKG  G PG PG
Sbjct: 815  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 874

Query: 881  EPG------LQGRPGELGPQGPTGPPGAKGQEGAHGAPG---AAGNPGAPGHVGAPGPSG 931
              G      + G+PG  G +GPTGP G++G  G  G PG    +G  G PG  G  GP G
Sbjct: 875  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 934

Query: 932  PPGSVGAPGLRGTPG---KDG------ERGEKGAAGEEGSPGP------------VGPRG 970
            P G VG PG +G PG   KDG      +RGE G  G+ G PGP             GP G
Sbjct: 935  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 994

Query: 971  DPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029
            + G PG PGPPG+ G  G  G  G+ G PGP G     G          G +   G+RG 
Sbjct: 995  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA--------GLRGFPGERGL 1046

Query: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG---LPGFPGPQGPAGRDGAPGNP 1086
            PG  G+PG +G  G G  GPPGP G PG++GS G+ G   LPG PGPQGP G  G  G P
Sbjct: 1047 PGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1104

Query: 1087 GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
            GE+GP G  G   +  P  +            PGP G  G PG  GDKG  G+PG++G++
Sbjct: 1105 GEKGPQGPAGRDGVQGPVGL------------PGPAGPAGSPGEDGDKGEIGEPGQKGSK 1152

Query: 1147 GKKGEAGPPGLPG------PPGIAGPQGSQGERGADGEVGQKGDQG---HPGVPGFMGPP 1197
            G KGE GPPG PG       PGIAG  G  G RG  G  GQKGD+G    PG PG +G  
Sbjct: 1153 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1212

Query: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG---------EEGKEGRD 1248
            G PGPPG  G  G  GP G  G PG  GP GP G  G  G PG         E+G+ G  
Sbjct: 1213 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1272

Query: 1249 GKPGPPGEPG------KAGEPGLPGPEGARGPPGFKGHTGDSGA------------PGPR 1290
            G PGPPGE G      + GE G  GP GA GPPG KG  GD G             PGP 
Sbjct: 1273 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1332

Query: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 1350
            GE G  G  G  G  G+DGD G  GP GP G  GPPG  G  G PG  G  G  G+KG+K
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1392

Query: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            GE G+ G PG  GP GP G  G+ G  G  G+PG  GE G  G  G  G  G  GPPG  
Sbjct: 1393 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1452

Query: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
            G  GDPG  G KGH GL+G  G PGE G  G  G PG  G PG +G+             
Sbjct: 1453 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----------- 1501

Query: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
                        +     P       G PGP GP G  G  G AG  G+ G PG  G  G
Sbjct: 1502 ------------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 1531 PSGPI 1535
            P G +
Sbjct: 1550 PPGEV 1554



 Score =  835 bits (2156), Expect = 0.0
 Identities = 563/1522 (36%), Positives = 700/1522 (45%), Gaps = 239/1522 (15%)

Query: 260  KRENGAQSSYVRMGSFPVVQSTEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQ 318
            K   G+ ++Y       +   T+ +FP G  P++++ + T + +K  +    ++  + ++
Sbjct: 65   KNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNE 121

Query: 319  YSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSL 378
            + I Q+ + +      +  +  G        +FR     ++ D  WH++A+S++ + V++
Sbjct: 122  HGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR---TVNIADGKWHRVAISVEKKTVTM 178

Query: 379  HIDCALVQTLPIE--ERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCC 436
             +DC    T P++  ER  +D  G TV G R+ D    + D+Q+ +I  D + A     C
Sbjct: 179  IVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAA--YDYC 236

Query: 437  DIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINC-------------------- 476
            +  S  C     +  P     Q P     ++  F K +                      
Sbjct: 237  EHYSPDCD----SSAPKAAQAQEPQIDEKKKSNFKKKMRTVATKSKEKSKKFTPPKSEKF 292

Query: 477  ------SCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPF------ 524
                  S  A  K ++GV   +     + + G +       P+   G     P       
Sbjct: 293  SSKKKKSYQASAKAKLGVKANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTE 352

Query: 525  ---------GQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL---------GEPGLPGEVG 566
                      Q +  E          GRD    + G+ GE           +P  P    
Sbjct: 353  EYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEE 412

Query: 567  MRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRG--EKGERGLDGFPGKPGDTGQQGRPGP 624
              GP  P         +   G  GE+G+KG     E G   ++G PG  G  G  G PG 
Sbjct: 413  F-GPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML-VEGPPGPAGPAGIMGPPGL 470

Query: 625  SGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA----PGPRGHQGAPGPP------ 674
             G  GP G+ GD GP G PG+PG+    +GL G  G     P   G  G+ GP       
Sbjct: 471  QGPTGPPGDPGDRGPPGRPGLPGA----DGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 526

Query: 675  --------------GARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720
                          G  GP+G  GR GP G  G  G KG+ G PG  G  G+QGPPGP G
Sbjct: 527  QAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTG 586

Query: 721  VPGPPG-PG--------GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPP---GTKG 768
             PG  G PG        G PG  G+ GF G PG PG  G  G+ GP GPPGPP   G +G
Sbjct: 587  KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRG 646

Query: 769  EPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD------QG 822
            E GE G  GLPG+ G RG +G +G  G PG+ G AG+ G PG  G  G +G+      QG
Sbjct: 647  EDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG 706

Query: 823  EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEP 882
              G  GLPG +G  G  GE GP G PGL G          +PG  GP G  G  G  GE 
Sbjct: 707  NPGPQGLPGPQGPIGPPGEKGPQGKPGLAG----------LPGADGPPGHPGKEGQSGEK 756

Query: 883  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942
            G  G PG  GP G  GP G KG +G  G  G+ G  G  G  G  G  G  G  G  G  
Sbjct: 757  GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816

Query: 943  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPL 1001
            G  G+DG  G KG AG  G PGP G  G+ G  G+PG PG  G+ G  G  G PG PG  
Sbjct: 817  GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 876

Query: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG----IGVAGPPGPSGPPG 1057
            G K A G          G    +G RG  G  GS G+RG  G     G +G  GP GPPG
Sbjct: 877  GEKGARG--------VAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPG 928

Query: 1058 DKGSPGSRGLPGFPGPQ---GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            ++G  G +G  GFPGP+   GP G+DG PG+PG+RG  G  G +    PG +        
Sbjct: 929  ERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV-------- 980

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
               P GP G  G  G +G  G PG PG +G  G  G+ G  G PGP GI+G  G  G RG
Sbjct: 981  -VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGP---PGADGIAGAAGPPGIQGSPGKEGPPGP-- 1229
              GE G  G QG PG+ G  GP G PGP   PG  G AG AGP G+ G PG +GPPGP  
Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099

Query: 1230 -------------------QGPSGLP------GIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264
                               QGP GLP      G PGE+G +G  G+PG  G  G  GE G
Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 1265 LPGPEGARGPPGFKGHTGDSGAPGPRGES---------------------GAMGLPGQEG 1303
             PGP G +GP G  G  G  G PGPRG+                      G  GLPG  G
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQKGSKGENGSPGLPG 1360
              G++GD GP GP GP GPRGP G NG+ G  G PG  G+    G+KG  GE G+PG PG
Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279

Query: 1361 FLGPRGPPGEPGEK---GVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKGQPG 1414
              G  GP GE GEK   G PG  G PG  G PG  G +G+P   G  GD GPPG  G  G
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG 1339

Query: 1415 DPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGK 1474
              G+ G KG  G  G  G PG +G  GPPGPPG+ G PG  G            Q E G 
Sbjct: 1340 QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGR--------QGEKGA 1391

Query: 1475 QLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP 1534
            + E       A+ PP       G  GP G PG +GL G  GP+GE G PG  G +GP GP
Sbjct: 1392 KGEAG-----AEGPPG-KTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGP 1445

Query: 1535 IGPKGERGAKGDPGAPG----VGLRGEMGPP---------GIPGQPGEPGYAKDGLPGIP 1581
            +GP G  G KGDPG+ G     GL G +GPP         G+PG  G PG   DG  GIP
Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG--GIP 1503

Query: 1582 GPQGETGPAGHPGLPGPPGPPG 1603
            GP G  GP G PGLPGP GP G
Sbjct: 1504 GPAGPLGPPGPPGLPGPQGPKG 1525



 Score =  782 bits (2020), Expect = 0.0
 Identities = 487/1157 (42%), Positives = 566/1157 (48%), Gaps = 199/1157 (17%)

Query: 632  GEKGDVGPAGPPGV--PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG-- 687
            G  G+ G  G P V  PG +V+        G PGP G  G  GPPG +GP GP G  G  
Sbjct: 432  GAYGEKGQKGEPAVVEPGMLVE--------GPPGPAGPAGIMGPPGLQGPTGPPGDPGDR 483

Query: 688  -PPGLQGLRGKKGDMGPPGIPGLL------------------------------GLQGPP 716
             PPG  GL G  G  GPPG   +L                               L+GPP
Sbjct: 484  GPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 543

Query: 717  GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED 776
            GP G+ G PGP G PG  G     G+ G PGP GP G  GP GP G PG +G PG  G  
Sbjct: 544  GPMGLTGRPGPVGGPGSSGA---KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 777  GLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836
            G+PG+PG +G+ G  GL G PG+KG  G  G  G PG  G+ G +GE GE+G  GL G+ 
Sbjct: 601  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 660

Query: 837  GEKGEAGPAGPPGLPGTTSLF----TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG 892
            G +G  GP G PG PG   +      P P+  G  GP+GE G PG  G PG QG PG  G
Sbjct: 661  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPK--GNMGPQGEPGPPGQQGNPGPQGLPGPQG 718

Query: 893  PQGPTGPPGAKGQEGAHGAPGAAGNPGAPG------HVGAPGPSGPPGSVGAPGLRGTPG 946
            P GP G  G +G+ G  G PGA G PG PG        GA GP GP G +G PG RG  G
Sbjct: 719  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 778

Query: 947  KDGERGEKGAAGEEGSPG---------------------------PVGPRGDPGAPGLPG 979
             DG RG KG+ GE+G  G                           P GP+G  G  G PG
Sbjct: 779  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 838

Query: 980  PPG----KGKDGEPGLRGSPGLPGPLGTKAACG-----KVRGSENCALGGQCVKGDRGAP 1030
            P G    KGK G PGL G PG  GP G+    G       +G+   A G    +G RG  
Sbjct: 839  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA-GKPGPRGQRGPT 897

Query: 1031 GIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAP 1083
            G  GS G+RG  G     G +G  GP GPPG++G  G +G  GFPGP+GP G   +DG P
Sbjct: 898  GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP 957

Query: 1084 GNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE 1143
            G+PG+RG  G  G +    PG +           P GP G  G  G +G  G PG PG +
Sbjct: 958  GHPGQRGETGFQGKTGPPGPGGVV---------GPQGPTGETGPIGERGHPGPPGPPGEQ 1008

Query: 1144 GTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP- 1202
            G  G  G+ G  G PGP GI+G  G  G RG  GE G  G QG PG+ G  GP G PGP 
Sbjct: 1009 GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1068

Query: 1203 --PGADGIAGAAGPPGIQGSPGKEGPPGP---------------------QGPSGLPG-- 1237
              PG  G AG AGP G+ G PG +GPPGP                     QGP GLPG  
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1128

Query: 1238 ----IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
                 PGE+G +G  G+PG  G  G  GE G PGP G +GP G  G  G  G PGPRG+ 
Sbjct: 1129 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188

Query: 1294 GAMG---------------------LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332
            G  G                     LPG  G  G++GD GP GP GP GPRGP G NG+ 
Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1248

Query: 1333 GSPGEPGPSGTPG---QKGSKGENGSPGLPGFLGPRGPPGEPGEKGV---PGKEGVPGKP 1386
            G  G PG  G+ G   +KG  GE G+PG PG  G  GP GE GEKG    PG  G PG  
Sbjct: 1249 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308

Query: 1387 GEPGFKGERGDPG---IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP 1443
            G PG  G +G+PG     GD GPPG  G  G  G+ G KG  G  G  G PG +G  GPP
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368

Query: 1444 GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG 1503
            GPPG+ G PG  G            Q E G + E       A+ PP       G  GP G
Sbjct: 1369 GPPGKRGPPGAAGAEGR--------QGEKGAKGEAG-----AEGPPG-KTGPVGPQGPAG 1414

Query: 1504 PPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMG 1559
             PG +GL G  GP+GE G PG  G +GP GP+GP G  G KGDPG+ G     GL G +G
Sbjct: 1415 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1474

Query: 1560 PPG---------IPGQPGEPGYAKDG-LPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609
            PPG         +PG  G PG   DG +PG  GP G  GP G PG  GP G  G   P+ 
Sbjct: 1475 PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG 1534

Query: 1610 CAYFASLAARPGNVKGP 1626
                + L   PG+   P
Sbjct: 1535 QKGDSGLPGPPGSPGPP 1551



 Score =  764 bits (1973), Expect = 0.0
 Identities = 465/1060 (43%), Positives = 527/1060 (49%), Gaps = 118/1060 (11%)

Query: 444  QVTVVTEPPPPPP--PQRP-PTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500
            Q  +    PP P     RP P  G    G         P G +G  G  GP G PG +G 
Sbjct: 534  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 593

Query: 501  IGAIGPVGAPGPKGEKGDVGIG--PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558
             GA G  G PG  G KGD G    P   G+KG +G  G  GPPG  G  GMRGE GE+G 
Sbjct: 594  PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 653

Query: 559  PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618
             GLPGE G RG  GP G PG PG+ G  G+ G  G KG  G +GE G    PG+ G+ G 
Sbjct: 654  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGP 710

Query: 619  QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARG 678
            QG PGP G  GP GEKG  G  G  G+PG+    +G  G  G  G  G +GA GPPG +G
Sbjct: 711  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGA----DGPPGHPGKEGQSGEKGALGPPGPQG 766

Query: 679  PIG---PEGRDGPPGLQGLRGKKGDMGPPGIPGL---------------LGLQGPPGPPG 720
            PIG   P G  G  G++GL+G KG+ G  G PG                +G +G  GP G
Sbjct: 767  PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 826

Query: 721  VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780
              G  GP G PG  G+ G  GK G PG  G PG+ GP G  G PG  G  GE+G  G+ G
Sbjct: 827  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 886

Query: 781  KPGLRGEIGE---------QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE-------- 823
            KPG RG+ G          +G  G+PG KG +G  G PG PG RG +G QG         
Sbjct: 887  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 946

Query: 824  ----KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGL 878
                 G+ GLPG  G RGE G  G  GPPG  G        P+ P GE GP GE+G PG 
Sbjct: 947  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-----PQGPTGETGPIGERGHPGP 1001

Query: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG---------APGHVGAPGP 929
            PG PG QG PG  G +G  G PG +G  G  G  G  G PG         APG  G  GP
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061

Query: 930  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 989
             GPPG VG+PG RG+ G  G  G  G  G +G PGP G +G PG  G  GP G+  DG  
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR--DGVQ 1119

Query: 990  GLRGSPGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVA 1047
            G  G PG  GP G+    G K    E    G +  KG+ G PG PG  G  G PGI G  
Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1179

Query: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG---------PPGKPGLS 1098
            G PGP G  G  G  G  G  GFPGP GP G  G PG PGE+G         PPG PG  
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239

Query: 1099 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK------PGREGTEGKKGEA 1152
                P            D P GPPG  G  G  G+KG PG+      PG  G  G KGE 
Sbjct: 1240 GPQGPNGA---------DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290

Query: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212
            G  G  GPPG AGP G++G  G DG  G  G  G PG PG   PPG PGP G DG+ G  
Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG---PPGEPGPAGQDGVGGDK 1347

Query: 1213 GPPGIQGSPG------KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266
            G  G  G PG      + GPPGP G     G PG  G EGR G+ G  GE G  G PG  
Sbjct: 1348 GEDGDPGQPGPPGPSGEAGPPGPPGKR---GPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1404

Query: 1267 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            GP G +GP G  G  G  G PGP GE G  G  GQ+G P      GP GP G  G +G P
Sbjct: 1405 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP------GPMGPPGLPGLKGDP 1458

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  G PG  G  G PG++G KG+ G P      G +G PG  G+ G+PG  G  G P
Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP------GTQGSPGAKGDGGIPGPAGPLGPP 1512

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG 1426
            G PG  G +G  G KG  GP G KG  G PG PG  G  G
Sbjct: 1513 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  212 bits (540), Expect = 2e-54
 Identities = 149/410 (36%), Positives = 171/410 (41%), Gaps = 94/410 (22%)

Query: 1242 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 1301
            E KE  D    PP E    G P     E         GH       G  GE G  G P  
Sbjct: 397  EYKEYEDKPTSPPNEEFGPGVPA----ETDITETSINGH-------GAYGEKGQKGEPAV 445

Query: 1302 EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361
               PG   + GP GP GP G  GPPG  G  G PG+PG  G PG+ G  G +G PG PG 
Sbjct: 446  VE-PGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 503

Query: 1362 L----------GPRGPP--------------------GEPGEKGVPGKEGVPGKPGEPGF 1391
            +          G +GP                     G PG  G+ G+ G  G PG  G 
Sbjct: 504  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGA 563

Query: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451
            KGE GDPG    +GP G +G PG  G PG +G  G  G +G+PGE G  G  G  G PG 
Sbjct: 564  KGESGDPG---PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 620

Query: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511
            PG +G                                    +  +G  GPPGPPG DG+ 
Sbjct: 621  PGDKGH-----------------------------------RGERGPQGPPGPPGDDGMR 645

Query: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571
            G  G +G  G PG+ G   P G +GP+G  GA G PG  GV      GPPG  G  G  G
Sbjct: 646  GEDGEIGPRGLPGEAG---PRGLLGPRGTPGAPGQPGMAGVD-----GPPGPKGNMGPQG 697

Query: 1572 YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621
                  PG PG QG  GP G PG  GP GPPG+  P      A L    G
Sbjct: 698  E-----PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 742


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  880 bits (2275), Expect = 0.0
 Identities = 526/1168 (45%), Positives = 599/1168 (51%), Gaps = 149/1168 (12%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG------IGPFGQGEKGEK 532
            PAG  G MG  G  G  GP GD G  GP G PG  G  G  G      + PF  G  G K
Sbjct: 407  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466

Query: 533  G-----------------SLGLPGPP------GRDGSKGMRGEPGELGEPGLPGEVGMRG 569
            G                  + L GPP      GR G  G  G  G  GE G PG  G RG
Sbjct: 467  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526

Query: 570  PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629
             QGPPG  G PG+ G PG  G RG  G  G KG+RG DG PG PGD G +G  GP G  G
Sbjct: 527  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 586

Query: 630  PQGE---KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD 686
            P G+   +G+ G  GP G+PG         G +G  GPRG  GAPG PG  G       D
Sbjct: 587  PPGDDGMRGEDGEIGPRGLPGEA-------GPRGLLGPRGTPGAPGQPGMAGV------D 633

Query: 687  GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP 746
            GPPG       KG+MGP G PG  G QG PGP G+PGP GP G PG  G  G PG  G P
Sbjct: 634  GPPG------PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP 687

Query: 747  GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 806
            G  GPPG  G  G  G  G  G PG +G  G PG  G++G  G +GL G  GEKGE G  
Sbjct: 688  GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 746

Query: 807  GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT----SLFTPH-P 861
              PGF G  G KGD+GE G++G  G  G  G KG AGP G PG  G       L  P  P
Sbjct: 747  --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804

Query: 862  RMPGEQGPKGEKGDPGLP------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP--- 912
              PG QGPKG  G PG P      G  G+ G+PG  G +GPTGP G++G  G  G P   
Sbjct: 805  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 864

Query: 913  GAAGNPGAPGHVGAPGPSGPPGSVGAPGLR---GTPGKD------GERGEKGAAGEEGSP 963
            G +G  G PG  G  GP GP G VG PG +   G PGKD      G+RGE G  G+ G P
Sbjct: 865  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 924

Query: 964  GP------------VGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKV 1010
            GP             GP G+ G PG PGPPG +G  G  G  G+ G PGP G     G  
Sbjct: 925  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 984

Query: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSR---GL 1067
                    G +   G+RG PG  G+PG +G  G G  GPPGP G PG++GS G+    GL
Sbjct: 985  --------GLRGFPGERGLPGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGL 1034

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL 1127
            PG PGPQGP G  G  G PGE+GP G  G   +  P  +            PGP G  G 
Sbjct: 1035 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL------------PGPAGPAGS 1082

Query: 1128 PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            PG  GDKG  G+PG++G++G KGE GP   PGPPG+ GP G+ G  G DGE G +G QG 
Sbjct: 1083 PGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1139

Query: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR 1247
             G  G  G  G PGPPG  G+ G  GPPG +G  G  GP GP GP G  G  G  G +G 
Sbjct: 1140 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP 1199

Query: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
             G PG  G  G  GE G PG  G  GPP      G++G  GP+GE G  G  G  G  G 
Sbjct: 1200 QGPPGSVGSVGGVGEKGEPGEAGNPGPP------GEAGVGGPKGERGEKGEAGPPGAAGP 1253

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGP--- 1364
             G  GP G  GP+G  GP G  G PG PGEPGP+G  G  G KGE+G PG PG  GP   
Sbjct: 1254 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
             GPPG PG++G PG  G  G+ GE G KGE G  G  G  GP G +G  G PG  G +G 
Sbjct: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI 1373

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             G +G QGLPG  G  GPPGP G PG PGL+G+  S            G++    L  L+
Sbjct: 1374 PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-----------GEKGHPGLIGLI 1422

Query: 1485 AQMPPAYMKSSQGRP---GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
                    K  +G P   G PG  G  G+PG AGP+G PG PG  G +GP G  G  G  
Sbjct: 1423 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482

Query: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569
            G KGD G P        GPPG PG PGE
Sbjct: 1483 GQKGDSGLP--------GPPGSPGPPGE 1502



 Score =  847 bits (2189), Expect = 0.0
 Identities = 519/1205 (43%), Positives = 596/1205 (49%), Gaps = 173/1205 (14%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM-------GLPGPKGDIG 502
            +P  PP  +  P   +E      +IN     GEKG+ G    +       G PGP G  G
Sbjct: 353  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 412

Query: 503  AIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGR----------DGSKG--- 548
             +GP G  GP G  GD G  GP   G  G  G+ GLPGPPG           DGSKG   
Sbjct: 413  IMGPPGLQGPTGPPGDPGDRGP--PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 470

Query: 549  -----------------MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591
                             +RG PG +G  G PG VG  G  G  G  G PG  G  G+QG 
Sbjct: 471  SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 530

Query: 592  RGEKGTRGEKGERGLDG---FPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
             G  G  G++G  G DG    PG+PG  G +G  G  G+ G +G +G+ GP GPPG PG 
Sbjct: 531  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 590

Query: 649  VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGK---KGDMGPPG 705
                +G++GE G  GPRG  G  GP G  GP G  G  G PG+ G+ G    KG+MGP G
Sbjct: 591  ----DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765
             PG  G QG PGP G+PGP GP G PG  G  G PG  G PG  GPPG  G  G  G  G
Sbjct: 647  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 706

Query: 766  TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825
              G PG +G  G PG  G++G  G +GL G  GEKGE G PG   F G  G KGD+GE G
Sbjct: 707  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG---FKGDMGLKGDRGEVG 763

Query: 826  ELGLPGLKGDRGEKGEAGPAGPPGLPGTTS----LFTPH-PRMPGEQGPKGEKGDPGLPG 880
            ++G  G  G  G KG AGP G PG  G       L  P  P  PG QGPKG  G PG PG
Sbjct: 764  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823

Query: 881  EPG------LQGRPGELGPQGPTGPPGAKGQEGAHGAPG---AAGNPGAPGHVGAPGPSG 931
              G      + G+PG  G +GPTGP G++G  G  G PG    +G  G PG  G  GP G
Sbjct: 824  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 883

Query: 932  PPGSVGAPGLRGTPG---KDG------ERGEKGAAGEEGSPGP------------VGPRG 970
            P G VG PG +G PG   KDG      +RGE G  G+ G PGP             GP G
Sbjct: 884  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 943

Query: 971  DPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029
            + G PG PGPPG+ G  G  G  G+ G PGP G     G          G +   G+RG 
Sbjct: 944  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA--------GLRGFPGERGL 995

Query: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG---LPGFPGPQGPAGRDGAPGNP 1086
            PG  G+PG +G  G G  GPPGP G PG++GS G+ G   LPG PGPQGP G  G  G P
Sbjct: 996  PGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1053

Query: 1087 GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
            GE+GP G  G   +  P  +            PGP G  G PG  GDKG  G+PG++G++
Sbjct: 1054 GEKGPQGPAGRDGVQGPVGL------------PGPAGPAGSPGEDGDKGEIGEPGQKGSK 1101

Query: 1147 GKKGEAGPPGLPG------PPGIAGPQGSQGERGADGEVGQKGDQG---HPGVPGFMGPP 1197
            G KGE GPPG PG       PGIAG  G  G RG  G  GQKGD+G    PG PG +G  
Sbjct: 1102 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1161

Query: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG---------EEGKEGRD 1248
            G PGPPG  G  G  GP G  G PG  GP GP G  G  G PG         E+G+ G  
Sbjct: 1162 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1221

Query: 1249 GKPGPPGEPG------KAGEPGLPGPEGARGPPGFKGHTGDSGA------------PGPR 1290
            G PGPPGE G      + GE G  GP GA GPPG KG  GD G             PGP 
Sbjct: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1281

Query: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 1350
            GE G  G  G  G  G+DGD G  GP GP G  GPPG  G  G PG  G  G  G+KG+K
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1341

Query: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            GE G+ G PG  GP GP G  G+ G  G  G+PG  GE G  G  G  G  G  GPPG  
Sbjct: 1342 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1401

Query: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
            G  GDPG  G KGH GL+G  G PGE G  G  G PG  G PG +G+             
Sbjct: 1402 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----------- 1450

Query: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
                        +     P       G PGP GP G  G  G AG  G+ G PG  G  G
Sbjct: 1451 ------------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 1531 PSGPI 1535
            P G +
Sbjct: 1499 PPGEV 1503



 Score =  813 bits (2100), Expect = 0.0
 Identities = 556/1516 (36%), Positives = 698/1516 (46%), Gaps = 229/1516 (15%)

Query: 260  KRENGAQSSYVRMGSFPVVQSTEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQ 318
            K   G+ ++Y       +   T+ +FP G  P++++ + T + +K  +    ++  + ++
Sbjct: 65   KNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNE 121

Query: 319  YSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSL 378
            + I Q+ + +      +  +  G        +FR     ++ D  WH++A+S++ + V++
Sbjct: 122  HGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR---TVNIADGKWHRVAISVEKKTVTM 178

Query: 379  HIDCALVQTLPIE--ERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCC 436
             +DC    T P++  ER  +D  G TV G R+ D    + D+Q+ +I  D + A     C
Sbjct: 179  IVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAAY--DYC 236

Query: 437  DIPSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPG 496
            +  S  C     +  P     Q P    +  +   +  N       + E           
Sbjct: 237  EHYSPDCD----SSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTE----------A 282

Query: 497  PKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGEL 556
            P+   G   P        E+   G     Q +  E          GRD    + G+ GE 
Sbjct: 283  PRHVSGTNEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEY 342

Query: 557  GEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
                       +  +  P    PP     PG+  E        +  E  ++G  G  G+ 
Sbjct: 343  DF------YEYKEYEDKP--TSPPNEEFGPGVPAET-------DITETSINGH-GAYGEK 386

Query: 617  GQQGRPGPSG----VAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG 672
            GQ+G P        V GP G  G  G  GPPG+             QG  GP G  G  G
Sbjct: 387  GQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGL-------------QGPTGPPGDPGDRG 433

Query: 673  PPGARGPIGPEGRDGPPG----LQGLRGKKGDMGPPGIP-----------GLLGLQGPPG 717
            PPG  G  G +G  GPPG    L    G  G  GP                 + L+GPPG
Sbjct: 434  PPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPG 493

Query: 718  PPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDG 777
            P G+ G PGP G PG  G     G+ G PGP GP G  GP GP G PG +G PG  G  G
Sbjct: 494  PMGLTGRPGPVGGPGSSGA---KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 550

Query: 778  LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRG 837
            +PG+PG +G+ G  GL G PG+KG  G  G  G PG  G+ G +GE GE+G  GL G+ G
Sbjct: 551  MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 610

Query: 838  EKGEAGPAGPPGLPGTTSLF----TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893
             +G  GP G PG PG   +      P P+  G  GP+GE G PG  G PG QG PG  GP
Sbjct: 611  PRGLLGPRGTPGAPGQPGMAGVDGPPGPK--GNMGPQGEPGPPGQQGNPGPQGLPGPQGP 668

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPG------HVGAPGPSGPPGSVGAPGLRGTPGK 947
             GP G  G +G+ G  G PGA G PG PG        GA GP GP G +G PG RG  G 
Sbjct: 669  IGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728

Query: 948  DGERGEKGAAGEEGSPG---------------------------PVGPRGDPGAPGLPGP 980
            DG RG KG+ GE+G  G                           P GP+G  G  G PGP
Sbjct: 729  DGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGP 788

Query: 981  PG----KGKDGEPGLRGSPGLPGPLGTKAACG-----KVRGSENCALGGQCVKGDRGAPG 1031
             G    KGK G PGL G PG  GP G+    G       +G+   A G    +G RG  G
Sbjct: 789  SGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA-GKPGPRGQRGPTG 847

Query: 1032 IPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPG 1084
              GS G+RG  G     G +G  GP GPPG++G  G +G  GFPGP+GP G   +DG PG
Sbjct: 848  PRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 907

Query: 1085 NPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREG 1144
            +PG+RG  G  G +    PG +           P GP G  G  G +G  G PG PG +G
Sbjct: 908  HPGQRGETGFQGKTGPPGPGGVV---------GPQGPTGETGPIGERGHPGPPGPPGEQG 958

Query: 1145 TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP-- 1202
              G  G+ G  G PGP GI+G  G  G RG  GE G  G QG PG+ G  GP G PGP  
Sbjct: 959  LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG 1018

Query: 1203 -PGADGIAGAAGPPGIQGSPGKEGPPGP---------------------QGPSGLPG--- 1237
             PG  G AG AGP G+ G PG +GPPGP                     QGP GLPG   
Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078

Query: 1238 ---IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294
                PGE+G +G  G+PG  G  G  GE G PGP G +GP G  G  G  G PGPRG+ G
Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1138

Query: 1295 AMG---------------------LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333
              G                     LPG  G  G++GD GP GP GP GPRGP G NG+ G
Sbjct: 1139 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198

Query: 1334 SPGEPGPSGTPG---QKGSKGENGSPGLPGFLGPRGPPGEPGEKGV---PGKEGVPGKPG 1387
              G PG  G+ G   +KG  GE G+PG PG  G  GP GE GEKG    PG  G PG  G
Sbjct: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258

Query: 1388 EPGFKGERGDPG---IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
             PG  G +G+PG     GD GPPG  G  G  G+ G KG  G  G  G PG +G  GPPG
Sbjct: 1259 PPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318

Query: 1445 PPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP 1504
            PPG+ G PG  G            Q E G + E       A+ PP       G  GP G 
Sbjct: 1319 PPGKRGPPGAAGAEGR--------QGEKGAKGEAG-----AEGPPG-KTGPVGPQGPAGK 1364

Query: 1505 PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMGP 1560
            PG +GL G  GP+GE G PG  G +GP GP+GP G  G KGDPG+ G     GL G +GP
Sbjct: 1365 PGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1424

Query: 1561 PG---------IPGQPGEPGYAKDG-LPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQC 1610
            PG         +PG  G PG   DG +PG  GP G  GP G PG  GP G  G   P+  
Sbjct: 1425 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1484

Query: 1611 AYFASLAARPGNVKGP 1626
               + L   PG+   P
Sbjct: 1485 KGDSGLPGPPGSPGPP 1500



 Score =  764 bits (1973), Expect = 0.0
 Identities = 465/1060 (43%), Positives = 527/1060 (49%), Gaps = 118/1060 (11%)

Query: 444  QVTVVTEPPPPPP--PQRP-PTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500
            Q  +    PP P     RP P  G    G         P G +G  G  GP G PG +G 
Sbjct: 483  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 542

Query: 501  IGAIGPVGAPGPKGEKGDVGIG--PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558
             GA G  G PG  G KGD G    P   G+KG +G  G  GPPG  G  GMRGE GE+G 
Sbjct: 543  PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 602

Query: 559  PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618
             GLPGE G RG  GP G PG PG+ G  G+ G  G KG  G +GE G    PG+ G+ G 
Sbjct: 603  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGP 659

Query: 619  QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARG 678
            QG PGP G  GP GEKG  G  G  G+PG+    +G  G  G  G  G +GA GPPG +G
Sbjct: 660  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGA----DGPPGHPGKEGQSGEKGALGPPGPQG 715

Query: 679  PIG---PEGRDGPPGLQGLRGKKGDMGPPGIPGL---------------LGLQGPPGPPG 720
            PIG   P G  G  G++GL+G KG+ G  G PG                +G +G  GP G
Sbjct: 716  PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 775

Query: 721  VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780
              G  GP G PG  G+ G  GK G PG  G PG+ GP G  G PG  G  GE+G  G+ G
Sbjct: 776  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 835

Query: 781  KPGLRGEIGE---------QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE-------- 823
            KPG RG+ G          +G  G+PG KG +G  G PG PG RG +G QG         
Sbjct: 836  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 895

Query: 824  ----KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGL 878
                 G+ GLPG  G RGE G  G  GPPG  G        P+ P GE GP GE+G PG 
Sbjct: 896  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-----PQGPTGETGPIGERGHPGP 950

Query: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG---------APGHVGAPGP 929
            PG PG QG PG  G +G  G PG +G  G  G  G  G PG         APG  G  GP
Sbjct: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010

Query: 930  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 989
             GPPG VG+PG RG+ G  G  G  G  G +G PGP G +G PG  G  GP G+  DG  
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR--DGVQ 1068

Query: 990  GLRGSPGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVA 1047
            G  G PG  GP G+    G K    E    G +  KG+ G PG PG  G  G PGI G  
Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1128

Query: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG---------PPGKPGLS 1098
            G PGP G  G  G  G  G  GFPGP GP G  G PG PGE+G         PPG PG  
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188

Query: 1099 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK------PGREGTEGKKGEA 1152
                P            D P GPPG  G  G  G+KG PG+      PG  G  G KGE 
Sbjct: 1189 GPQGPNGA---------DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239

Query: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212
            G  G  GPPG AGP G++G  G DG  G  G  G PG PG   PPG PGP G DG+ G  
Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG---PPGEPGPAGQDGVGGDK 1296

Query: 1213 GPPGIQGSPG------KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266
            G  G  G PG      + GPPGP G     G PG  G EGR G+ G  GE G  G PG  
Sbjct: 1297 GEDGDPGQPGPPGPSGEAGPPGPPGKR---GPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1353

Query: 1267 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            GP G +GP G  G  G  G PGP GE G  G  GQ+G P      GP GP G  G +G P
Sbjct: 1354 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP------GPMGPPGLPGLKGDP 1407

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  G PG  G  G PG++G KG+ G P      G +G PG  G+ G+PG  G  G P
Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP------GTQGSPGAKGDGGIPGPAGPLGPP 1461

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG 1426
            G PG  G +G  G KG  GP G KG  G PG PG  G  G
Sbjct: 1462 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  880 bits (2275), Expect = 0.0
 Identities = 526/1168 (45%), Positives = 599/1168 (51%), Gaps = 149/1168 (12%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG------IGPFGQGEKGEK 532
            PAG  G MG  G  G  GP GD G  GP G PG  G  G  G      + PF  G  G K
Sbjct: 446  PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505

Query: 533  G-----------------SLGLPGPP------GRDGSKGMRGEPGELGEPGLPGEVGMRG 569
            G                  + L GPP      GR G  G  G  G  GE G PG  G RG
Sbjct: 506  GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565

Query: 570  PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG 629
             QGPPG  G PG+ G PG  G RG  G  G KG+RG DG PG PGD G +G  GP G  G
Sbjct: 566  VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625

Query: 630  PQGE---KGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD 686
            P G+   +G+ G  GP G+PG         G +G  GPRG  GAPG PG  G       D
Sbjct: 626  PPGDDGMRGEDGEIGPRGLPGEA-------GPRGLLGPRGTPGAPGQPGMAGV------D 672

Query: 687  GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP 746
            GPPG       KG+MGP G PG  G QG PGP G+PGP GP G PG  G  G PG  G P
Sbjct: 673  GPPG------PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLP 726

Query: 747  GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 806
            G  GPPG  G  G  G  G  G PG +G  G PG  G++G  G +GL G  GEKGE G  
Sbjct: 727  GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 785

Query: 807  GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT----SLFTPH-P 861
              PGF G  G KGD+GE G++G  G  G  G KG AGP G PG  G       L  P  P
Sbjct: 786  --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843

Query: 862  RMPGEQGPKGEKGDPGLP------GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP--- 912
              PG QGPKG  G PG P      G  G+ G+PG  G +GPTGP G++G  G  G P   
Sbjct: 844  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 903

Query: 913  GAAGNPGAPGHVGAPGPSGPPGSVGAPGLR---GTPGKD------GERGEKGAAGEEGSP 963
            G +G  G PG  G  GP GP G VG PG +   G PGKD      G+RGE G  G+ G P
Sbjct: 904  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 963

Query: 964  GP------------VGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKV 1010
            GP             GP G+ G PG PGPPG +G  G  G  G+ G PGP G     G  
Sbjct: 964  GPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA 1023

Query: 1011 RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSR---GL 1067
                    G +   G+RG PG  G+PG +G  G G  GPPGP G PG++GS G+    GL
Sbjct: 1024 --------GLRGFPGERGLPGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGL 1073

Query: 1068 PGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL 1127
            PG PGPQGP G  G  G PGE+GP G  G   +  P  +            PGP G  G 
Sbjct: 1074 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGL------------PGPAGPAGS 1121

Query: 1128 PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 1187
            PG  GDKG  G+PG++G++G KGE GP   PGPPG+ GP G+ G  G DGE G +G QG 
Sbjct: 1122 PGEDGDKGEIGEPGQKGSKGDKGENGP---PGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1178

Query: 1188 PGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGR 1247
             G  G  G  G PGPPG  G+ G  GPPG +G  G  GP GP GP G  G  G  G +G 
Sbjct: 1179 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP 1238

Query: 1248 DGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGK 1307
             G PG  G  G  GE G PG  G  GPP      G++G  GP+GE G  G  G  G  G 
Sbjct: 1239 QGPPGSVGSVGGVGEKGEPGEAGNPGPP------GEAGVGGPKGERGEKGEAGPPGAAGP 1292

Query: 1308 DGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGP--- 1364
             G  GP G  GP+G  GP G  G PG PGEPGP+G  G  G KGE+G PG PG  GP   
Sbjct: 1293 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGH 1424
             GPPG PG++G PG  G  G+ GE G KGE G  G  G  GP G +G  G PG  G +G 
Sbjct: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGI 1412

Query: 1425 TGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLL 1484
             G +G QGLPG  G  GPPGP G PG PGL+G+  S            G++    L  L+
Sbjct: 1413 PGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-----------GEKGHPGLIGLI 1461

Query: 1485 AQMPPAYMKSSQGRP---GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
                    K  +G P   G PG  G  G+PG AGP+G PG PG  G +GP G  G  G  
Sbjct: 1462 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521

Query: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGE 1569
            G KGD G P        GPPG PG PGE
Sbjct: 1522 GQKGDSGLP--------GPPGSPGPPGE 1541



 Score =  847 bits (2189), Expect = 0.0
 Identities = 519/1205 (43%), Positives = 596/1205 (49%), Gaps = 173/1205 (14%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM-------GLPGPKGDIG 502
            +P  PP  +  P   +E      +IN     GEKG+ G    +       G PGP G  G
Sbjct: 392  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 451

Query: 503  AIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGR----------DGSKG--- 548
             +GP G  GP G  GD G  GP   G  G  G+ GLPGPPG           DGSKG   
Sbjct: 452  IMGPPGLQGPTGPPGDPGDRGP--PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTI 509

Query: 549  -----------------MRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591
                             +RG PG +G  G PG VG  G  G  G  G PG  G  G+QG 
Sbjct: 510  SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGP 569

Query: 592  RGEKGTRGEKGERGLDG---FPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGS 648
             G  G  G++G  G DG    PG+PG  G +G  G  G+ G +G +G+ GP GPPG PG 
Sbjct: 570  PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 629

Query: 649  VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGK---KGDMGPPG 705
                +G++GE G  GPRG  G  GP G  GP G  G  G PG+ G+ G    KG+MGP G
Sbjct: 630  ----DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765
             PG  G QG PGP G+PGP GP G PG  G  G PG  G PG  GPPG  G  G  G  G
Sbjct: 686  EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKG 745

Query: 766  TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 825
              G PG +G  G PG  G++G  G +GL G  GEKGE G PG   F G  G KGD+GE G
Sbjct: 746  ALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG---FKGDMGLKGDRGEVG 802

Query: 826  ELGLPGLKGDRGEKGEAGPAGPPGLPGTTS----LFTPH-PRMPGEQGPKGEKGDPGLPG 880
            ++G  G  G  G KG AGP G PG  G       L  P  P  PG QGPKG  G PG PG
Sbjct: 803  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862

Query: 881  EPG------LQGRPGELGPQGPTGPPGAKGQEGAHGAPG---AAGNPGAPGHVGAPGPSG 931
              G      + G+PG  G +GPTGP G++G  G  G PG    +G  G PG  G  GP G
Sbjct: 863  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 922

Query: 932  PPGSVGAPGLRGTPG---KDG------ERGEKGAAGEEGSPGP------------VGPRG 970
            P G VG PG +G PG   KDG      +RGE G  G+ G PGP             GP G
Sbjct: 923  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 982

Query: 971  DPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029
            + G PG PGPPG+ G  G  G  G+ G PGP G     G          G +   G+RG 
Sbjct: 983  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPA--------GLRGFPGERGL 1034

Query: 1030 PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRG---LPGFPGPQGPAGRDGAPGNP 1086
            PG  G+PG +G  G G  GPPGP G PG++GS G+ G   LPG PGPQGP G  G  G P
Sbjct: 1035 PGAQGAPGLKG--GEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAP 1092

Query: 1087 GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
            GE+GP G  G   +  P  +            PGP G  G PG  GDKG  G+PG++G++
Sbjct: 1093 GEKGPQGPAGRDGVQGPVGL------------PGPAGPAGSPGEDGDKGEIGEPGQKGSK 1140

Query: 1147 GKKGEAGPPGLPG------PPGIAGPQGSQGERGADGEVGQKGDQG---HPGVPGFMGPP 1197
            G KGE GPPG PG       PGIAG  G  G RG  G  GQKGD+G    PG PG +G  
Sbjct: 1141 GDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQ 1200

Query: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG---------EEGKEGRD 1248
            G PGPPG  G  G  GP G  G PG  GP GP G  G  G PG         E+G+ G  
Sbjct: 1201 GLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEA 1260

Query: 1249 GKPGPPGEPG------KAGEPGLPGPEGARGPPGFKGHTGDSGA------------PGPR 1290
            G PGPPGE G      + GE G  GP GA GPPG KG  GD G             PGP 
Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPP 1320

Query: 1291 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 1350
            GE G  G  G  G  G+DGD G  GP GP G  GPPG  G  G PG  G  G  G+KG+K
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAK 1380

Query: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            GE G+ G PG  GP GP G  G+ G  G  G+PG  GE G  G  G  G  G  GPPG  
Sbjct: 1381 GEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP 1440

Query: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
            G  GDPG  G KGH GL+G  G PGE G  G  G PG  G PG +G+             
Sbjct: 1441 GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGG----------- 1489

Query: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
                        +     P       G PGP GP G  G  G AG  G+ G PG  G  G
Sbjct: 1490 ------------IPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 1531 PSGPI 1535
            P G +
Sbjct: 1538 PPGEV 1542



 Score =  782 bits (2020), Expect = 0.0
 Identities = 487/1157 (42%), Positives = 566/1157 (48%), Gaps = 199/1157 (17%)

Query: 632  GEKGDVGPAGPPGV--PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG-- 687
            G  G+ G  G P V  PG +V+        G PGP G  G  GPPG +GP GP G  G  
Sbjct: 420  GAYGEKGQKGEPAVVEPGMLVE--------GPPGPAGPAGIMGPPGLQGPTGPPGDPGDR 471

Query: 688  -PPGLQGLRGKKGDMGPPGIPGLL------------------------------GLQGPP 716
             PPG  GL G  G  GPPG   +L                               L+GPP
Sbjct: 472  GPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPP 531

Query: 717  GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED 776
            GP G+ G PGP G PG  G     G+ G PGP GP G  GP GP G PG +G PG  G  
Sbjct: 532  GPMGLTGRPGPVGGPGSSGA---KGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 777  GLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836
            G+PG+PG +G+ G  GL G PG+KG  G  G  G PG  G+ G +GE GE+G  GL G+ 
Sbjct: 589  GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 648

Query: 837  GEKGEAGPAGPPGLPGTTSLF----TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG 892
            G +G  GP G PG PG   +      P P+  G  GP+GE G PG  G PG QG PG  G
Sbjct: 649  GPRGLLGPRGTPGAPGQPGMAGVDGPPGPK--GNMGPQGEPGPPGQQGNPGPQGLPGPQG 706

Query: 893  PQGPTGPPGAKGQEGAHGAPGAAGNPGAPG------HVGAPGPSGPPGSVGAPGLRGTPG 946
            P GP G  G +G+ G  G PGA G PG PG        GA GP GP G +G PG RG  G
Sbjct: 707  PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766

Query: 947  KDGERGEKGAAGEEGSPG---------------------------PVGPRGDPGAPGLPG 979
             DG RG KG+ GE+G  G                           P GP+G  G  G PG
Sbjct: 767  ADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPG 826

Query: 980  PPG----KGKDGEPGLRGSPGLPGPLGTKAACG-----KVRGSENCALGGQCVKGDRGAP 1030
            P G    KGK G PGL G PG  GP G+    G       +G+   A G    +G RG  
Sbjct: 827  PSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA-GKPGPRGQRGPT 885

Query: 1031 GIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAP 1083
            G  GS G+RG  G     G +G  GP GPPG++G  G +G  GFPGP+GP G   +DG P
Sbjct: 886  GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLP 945

Query: 1084 GNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE 1143
            G+PG+RG  G  G +    PG +           P GP G  G  G +G  G PG PG +
Sbjct: 946  GHPGQRGETGFQGKTGPPGPGGVV---------GPQGPTGETGPIGERGHPGPPGPPGEQ 996

Query: 1144 GTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP- 1202
            G  G  G+ G  G PGP GI+G  G  G RG  GE G  G QG PG+ G  GP G PGP 
Sbjct: 997  GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV 1056

Query: 1203 --PGADGIAGAAGPPGIQGSPGKEGPPGP---------------------QGPSGLPG-- 1237
              PG  G AG AGP G+ G PG +GPPGP                     QGP GLPG  
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA 1116

Query: 1238 ----IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
                 PGE+G +G  G+PG  G  G  GE G PGP G +GP G  G  G  G PGPRG+ 
Sbjct: 1117 GPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176

Query: 1294 GAMG---------------------LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332
            G  G                     LPG  G  G++GD GP GP GP GPRGP G NG+ 
Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD 1236

Query: 1333 GSPGEPGPSGTPG---QKGSKGENGSPGLPGFLGPRGPPGEPGEKGV---PGKEGVPGKP 1386
            G  G PG  G+ G   +KG  GE G+PG PG  G  GP GE GEKG    PG  G PG  
Sbjct: 1237 GPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296

Query: 1387 GEPGFKGERGDPG---IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP 1443
            G PG  G +G+PG     GD GPPG  G  G  G+ G KG  G  G  G PG +G  GPP
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356

Query: 1444 GPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPG 1503
            GPPG+ G PG  G            Q E G + E       A+ PP       G  GP G
Sbjct: 1357 GPPGKRGPPGAAGAEGR--------QGEKGAKGEAG-----AEGPPG-KTGPVGPQGPAG 1402

Query: 1504 PPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEMG 1559
             PG +GL G  GP+GE G PG  G +GP GP+GP G  G KGDPG+ G     GL G +G
Sbjct: 1403 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIG 1462

Query: 1560 PPG---------IPGQPGEPGYAKDG-LPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609
            PPG         +PG  G PG   DG +PG  GP G  GP G PG  GP G  G   P+ 
Sbjct: 1463 PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAG 1522

Query: 1610 CAYFASLAARPGNVKGP 1626
                + L   PG+   P
Sbjct: 1523 QKGDSGLPGPPGSPGPP 1539



 Score =  764 bits (1973), Expect = 0.0
 Identities = 465/1060 (43%), Positives = 527/1060 (49%), Gaps = 118/1060 (11%)

Query: 444  QVTVVTEPPPPPP--PQRP-PTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGD 500
            Q  +    PP P     RP P  G    G         P G +G  G  GP G PG +G 
Sbjct: 522  QARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGR 581

Query: 501  IGAIGPVGAPGPKGEKGDVGIG--PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558
             GA G  G PG  G KGD G    P   G+KG +G  G  GPPG  G  GMRGE GE+G 
Sbjct: 582  PGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGP 641

Query: 559  PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618
             GLPGE G RG  GP G PG PG+ G  G+ G  G KG  G +GE G    PG+ G+ G 
Sbjct: 642  RGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP---PGQQGNPGP 698

Query: 619  QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARG 678
            QG PGP G  GP GEKG  G  G  G+PG+    +G  G  G  G  G +GA GPPG +G
Sbjct: 699  QGLPGPQGPIGPPGEKGPQGKPGLAGLPGA----DGPPGHPGKEGQSGEKGALGPPGPQG 754

Query: 679  PIG---PEGRDGPPGLQGLRGKKGDMGPPGIPGL---------------LGLQGPPGPPG 720
            PIG   P G  G  G++GL+G KG+ G  G PG                +G +G  GP G
Sbjct: 755  PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 814

Query: 721  VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780
              G  GP G PG  G+ G  GK G PG  G PG+ GP G  G PG  G  GE+G  G+ G
Sbjct: 815  PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874

Query: 781  KPGLRGEIGE---------QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE-------- 823
            KPG RG+ G          +G  G+PG KG +G  G PG PG RG +G QG         
Sbjct: 875  KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 934

Query: 824  ----KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGL 878
                 G+ GLPG  G RGE G  G  GPPG  G        P+ P GE GP GE+G PG 
Sbjct: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVG-----PQGPTGETGPIGERGHPGP 989

Query: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG---------APGHVGAPGP 929
            PG PG QG PG  G +G  G PG +G  G  G  G  G PG         APG  G  GP
Sbjct: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049

Query: 930  SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 989
             GPPG VG+PG RG+ G  G  G  G  G +G PGP G +G PG  G  GP G+  DG  
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR--DGVQ 1107

Query: 990  GLRGSPGLPGPLGTKAACG-KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVA 1047
            G  G PG  GP G+    G K    E    G +  KG+ G PG PG  G  G PGI G  
Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1167

Query: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERG---------PPGKPGLS 1098
            G PGP G  G  G  G  G  GFPGP GP G  G PG PGE+G         PPG PG  
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227

Query: 1099 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK------PGREGTEGKKGEA 1152
                P            D P GPPG  G  G  G+KG PG+      PG  G  G KGE 
Sbjct: 1228 GPQGPNGA---------DGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278

Query: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212
            G  G  GPPG AGP G++G  G DG  G  G  G PG PG   PPG PGP G DG+ G  
Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG---PPGEPGPAGQDGVGGDK 1335

Query: 1213 GPPGIQGSPG------KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266
            G  G  G PG      + GPPGP G     G PG  G EGR G+ G  GE G  G PG  
Sbjct: 1336 GEDGDPGQPGPPGPSGEAGPPGPPGKR---GPPGAAGAEGRQGEKGAKGEAGAEGPPGKT 1392

Query: 1267 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            GP G +GP G  G  G  G PGP GE G  G  GQ+G P      GP GP G  G +G P
Sbjct: 1393 GPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP------GPMGPPGLPGLKGDP 1446

Query: 1327 GKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 1386
            G  G  G PG  G  G PG++G KG+ G P      G +G PG  G+ G+PG  G  G P
Sbjct: 1447 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP------GTQGSPGAKGDGGIPGPAGPLGPP 1500

Query: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTG 1426
            G PG  G +G  G KG  GP G KG  G PG PG  G  G
Sbjct: 1501 GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  212 bits (540), Expect = 2e-54
 Identities = 149/410 (36%), Positives = 171/410 (41%), Gaps = 94/410 (22%)

Query: 1242 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 1301
            E KE  D    PP E    G P     E         GH       G  GE G  G P  
Sbjct: 385  EYKEYEDKPTSPPNEEFGPGVPA----ETDITETSINGH-------GAYGEKGQKGEPAV 433

Query: 1302 EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361
               PG   + GP GP GP G  GPPG  G  G PG+PG  G PG+ G  G +G PG PG 
Sbjct: 434  VE-PGMLVE-GPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 491

Query: 1362 L----------GPRGPP--------------------GEPGEKGVPGKEGVPGKPGEPGF 1391
            +          G +GP                     G PG  G+ G+ G  G PG  G 
Sbjct: 492  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGA 551

Query: 1392 KGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGF 1451
            KGE GDPG    +GP G +G PG  G PG +G  G  G +G+PGE G  G  G  G PG 
Sbjct: 552  KGESGDPG---PQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL 608

Query: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511
            PG +G                                    +  +G  GPPGPPG DG+ 
Sbjct: 609  PGDKGH-----------------------------------RGERGPQGPPGPPGDDGMR 633

Query: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571
            G  G +G  G PG+ G   P G +GP+G  GA G PG  GV      GPPG  G  G  G
Sbjct: 634  GEDGEIGPRGLPGEAG---PRGLLGPRGTPGAPGQPGMAGVD-----GPPGPKGNMGPQG 685

Query: 1572 YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621
                  PG PG QG  GP G PG  GP GPPG+  P      A L    G
Sbjct: 686  E-----PGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 730



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 39/174 (22%), Positives = 85/174 (48%), Gaps = 9/174 (5%)

Query: 260 KRENGAQSSYVRMGSFPVVQSTEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQ 318
           K   G+ ++Y       +   T+ +FP G  P++++ + T + +K  +    ++  + ++
Sbjct: 65  KNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS---FLLSIYNE 121

Query: 319 YSIPQVSIRLDGENKAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSL 378
           + I Q+ + +      +  +  G        +FR     ++ D  WH++A+S++ + V++
Sbjct: 122 HGIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFR---TVNIADGKWHRVAISVEKKTVTM 178

Query: 379 HIDCALVQTLPIE--ERENIDIQGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHA 430
            +DC    T P++  ER  +D  G TV G R+ D    + D+Q+ +I  D + A
Sbjct: 179 IVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPKAA 232


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  879 bits (2271), Expect = 0.0
 Identities = 537/1236 (43%), Positives = 610/1236 (49%), Gaps = 239/1236 (19%)

Query: 490  GPMGLPGPKGDI-GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKG 548
            GP G  G  GDI   +GP G PGP+G  G+ G     +G++G+KG  G PGP GRDG  G
Sbjct: 32   GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG----PRGDRGDKGEKGAPGPRGRDGEPG 87

Query: 549  MRGEPGELGEPGLPGEVG------------------------MRGPQGPPGLPGPPGRVG 584
              G PG  G PG PG  G                        M+GP GP G  GPPG  G
Sbjct: 88   TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147

Query: 585  APGLQ------GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVG 638
            APG Q      GE GE G  G  G RG  G PGKPGD G+ G+PG +G  GP G +G  G
Sbjct: 148  APGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 207

Query: 639  PAGPPGVPGSVVQQ-----EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQG 693
              G PG+PG    +     +G KGE GAPG +G  G+PG  G+ GP+GP         +G
Sbjct: 208  FPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP---------RG 258

Query: 694  LRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPG 753
            L G++G  GP G  G  G  G PGP G PGP GP G PG PG  G  G+ GP G  GP G
Sbjct: 259  LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318

Query: 754  KDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP---------------- 797
              GP G PG PG+ G  G  G  G  G PG +G  G  G+AG P                
Sbjct: 319  AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 378

Query: 798  --GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP------GLKGDRGEKGEAGPAGPP- 848
              G KG+ G PG  GF G +G KG+ G  G  G P      G +G RGE G  GP GPP 
Sbjct: 379  PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 438

Query: 849  --------GLPGTTSLFTPHPRMPGEQ------GPKGEKGDPGLPGEP------GLQGRP 888
                    G PG   L  P    PGE+      GPKG  GDPG PGEP      GL GRP
Sbjct: 439  ERGAPGNRGFPGQDGLAGP-KGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 497

Query: 889  GELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP---SGPPGSV------GAP 939
            G+ GPQG  GP GA G++G  G PG  G  G PG +G PGP   +G PG        GAP
Sbjct: 498  GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557

Query: 940  GLRGTPGKDGER------GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK----GKDGEP 989
            GLRG PGKDGE       G  G AGE G  G  GP G  G PG PGPPG+    G  G P
Sbjct: 558  GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 990  GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGP 1049
            G  G+PGL GP G +   G+ RGS     G Q ++G RG PG PG+ G +G    G AGP
Sbjct: 618  GEAGAPGLVGPRGERGFPGE-RGSP----GAQGLQGPRGLPGTPGTDGPKG--ASGPAGP 670

Query: 1050 PGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLL 1109
            PG  GPPG +G PG RG  G  GP+G        G+ GE+GP G PG       G   L 
Sbjct: 671  PGAQGPPGLQGMPGERGAAGIAGPKGDR------GDVGEKGPEGAPG-----KDGGRGLT 719

Query: 1110 AKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGS 1169
                    P GPPG  G  G KG+ G PG  G  G  G  GE G  G PGP G AGP G+
Sbjct: 720  G-------PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGA 772

Query: 1170 QGERGADGEVGQKGDQGHPGVPGFMGPPGNP------------------GPPGADGIAGA 1211
             G+ GA GE G+ G +G  G PG  GP G P                  GPPGA G  GA
Sbjct: 773  DGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGA 832

Query: 1212 A---GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP---GPPGEPGKAGEPGL 1265
            A   GPPG  G+PG  GPPGP G  G  G  G+ G  GR G+P   GP G PG+ GEPG 
Sbjct: 833  AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD 892

Query: 1266 PGPEGARGPP---GFKGHTGDSGAPGPRGESGAMGL------PGQEGLPGKDGDTGPTGP 1316
             GP GA GPP   G  G  G  G PG RGE G  GL      PG++G PG  GD GP GP
Sbjct: 893  DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGP 952

Query: 1317 QGP---QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGE 1373
             GP    GP G PG+ GSPG+ G PG  G  G KG +GE G+ G PG  GP G PG  G 
Sbjct: 953  VGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 1374 KGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433
             G  G  G  G  G  G  G  G  GI+G +GP G KG+ G+PG  G KGH G  G QGL
Sbjct: 1013 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL 1072

Query: 1434 PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMK 1493
            P      GPPGP G  G  G                                   PA   
Sbjct: 1073 P------GPPGPSGDQGASG-----------------------------------PAGPS 1091

Query: 1494 SSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVG 1553
              +G PGP GP GKDG  G  GP+G PG  G+ G  GP+GP            PG P   
Sbjct: 1092 GPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGP------------PGNP--- 1136

Query: 1554 LRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGP 1589
                 GPPG PG PG PG       G+ GP+ E GP
Sbjct: 1137 -----GPPGPPGPPG-PGIDMSAFAGL-GPR-EKGP 1164



 Score =  865 bits (2234), Expect = 0.0
 Identities = 525/1202 (43%), Positives = 602/1202 (50%), Gaps = 194/1202 (16%)

Query: 552  EPGELGEPGLPGEV-GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFP 610
            +PG  G+ G PG++  + GP+GPPG  GP G  G  G +G++GEKG  G +G  G  G P
Sbjct: 30   QPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 611  GKPGDTGQQGRPGPSGVAGP---------------------QGEKGDVGPAGPPGVPGSV 649
            G PG  G  G PGP G+ G                      QG  G +GP GPPG     
Sbjct: 90   GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPG----- 144

Query: 650  VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGL 709
                      GAPGP+G QG PG PG  G  GP G  GPPG  G   K GD G  G PG 
Sbjct: 145  --------PAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPG---KPGDDGEAGKPGK 193

Query: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPG------KPGPPGPTGPPGKDGPNGPPGP 763
             G +GPPGP G  G PG  G PG+ G  G+PG      + G PG  G  G  G NG PGP
Sbjct: 194  AGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP 253

Query: 764  PGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE 823
             G +G PGERG  G  G  G RG  G+ G AG PG  G AG PG PG PG +GE G  G 
Sbjct: 254  MGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGA 313

Query: 824  KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE-- 881
            +G  G  G +G+ G  G  GPAG  G PGT  +    P   G  G  G  G PG PG   
Sbjct: 314  RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGI----PGAKGSAGAPGIAGAPGFPGPRG 369

Query: 882  -PGLQGRPGELGPQGPTGPPGA---KGQEGAHGAPGAAGNPGAPGHVGAPG--------- 928
             PG QG  G LGP+G TG PG    KG++G  G PG AG  GAPG  G  G         
Sbjct: 370  PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429

Query: 929  ---PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRG---DPGAPGLPGPPG 982
               P GPPG  GAPG RG PG+DG  G KGA GE G  G  GP+G   DPG PG PG PG
Sbjct: 430  GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 489

Query: 983  K----------------GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGD 1026
                             G  G PG  G PG PGP G +   G +         G+   G 
Sbjct: 490  ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE--PGK 547

Query: 1027 RGAPGIPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082
             G  G+PG+PG RG PG     G AGPPGP+GP G++G  G+ G  GF G  GP G  G 
Sbjct: 548  AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607

Query: 1083 PGNPGERGPPGKPGLSSLLSP-GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 1141
             G PG++G PG+ G   L+ P G+             PG  G PG  G +G +G+PG PG
Sbjct: 608  GGKPGDQGVPGEAGAPGLVGPRGERGF----------PGERGSPGAQGLQGPRGLPGTPG 657

Query: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201
             +G +G  G AGPPG  GPPG+   QG  GERGA G  G KGD+G  G  G  G PG  G
Sbjct: 658  TDGPKGASGPAGPPGAQGPPGL---QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714

Query: 1202 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAG 1261
              G  G  G  GP G  G  G+ GPPGP G +G  G PGE G+ G      PPG  G AG
Sbjct: 715  GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG------PPGPAGFAG 768

Query: 1262 EPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA------MGLPGQEGLPGKDGDTGPTG 1315
             PG  G  GA+G  G  G  GD+GAPGP+G SGA       G+ G +G  G  G  G TG
Sbjct: 769  PPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATG 828

Query: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL---PGFLGPRGPPGEPG 1372
              G  G  GPPG NG+PG PG PGPSG  G KG++G++G PG    PG  GP GPPGE G
Sbjct: 829  FPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888

Query: 1373 EKGVPGKEGVPGKPGE------------PGFKGERGDPGIKGDKGPPGGKGQP---GDPG 1417
            E G  G  G  G PG             PG +GERG PG+ G  G PG +G P   GD G
Sbjct: 889  EPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG 948

Query: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 1477
             PG  G  GL GP G PG  G  G  GPPG+ G  G++G+           + E G    
Sbjct: 949  PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD-----------RGETG---- 993

Query: 1478 TRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA---GPMGEPGRPGQGGLEGPSGP 1534
              +    A  PP       G PGP GP GK G  G A   GPMG  G  G  G++GP GP
Sbjct: 994  -AVGAPGAPGPP-------GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045

Query: 1535 IGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYA----------------K 1574
             G KGE G  G+ G  G     GL+G  GPPG  G  G  G A                K
Sbjct: 1046 RGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGK 1105

Query: 1575 DGLPGIPGP---------QGETGPAGHPGLPGPPGPPGQCDPS-QCAYFASLAARPGNVK 1624
            DG  GIPGP          GETGPAG PG PGPPGPPG   P    + FA L  R    K
Sbjct: 1106 DGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPRE---K 1162

Query: 1625 GP 1626
            GP
Sbjct: 1163 GP 1164



 Score =  742 bits (1916), Expect = 0.0
 Identities = 432/931 (46%), Positives = 487/931 (52%), Gaps = 75/931 (8%)

Query: 480  AGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFG-QGEKGEKGSLGL 537
            AG +G  G  GP G PGP G  G  G  GAPG KGE G  G  GP G QG +GE G+ G 
Sbjct: 272  AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS 331

Query: 538  PGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT 597
            PGP G  G+ G  G PG  G  G PG  G  G  GP G PGP G  G  G +G+ GE G 
Sbjct: 332  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 391

Query: 598  RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ-----Q 652
             G KGE+G  G PG  G  G  G  G  G  G +GE G VGP GPPG  G+        Q
Sbjct: 392  AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 451

Query: 653  EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGL 712
            +GL G +GAPG RG  G  GP GA G  G  G  G PG +GL G+ GD GP G    +G 
Sbjct: 452  DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG---KVGP 508

Query: 713  QGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE 772
             G PG  G PGPPGP G+ G PG +GFPG   P G  G PGK G  G PG PG +G PG+
Sbjct: 509  SGAPGEDGRPGPPGPQGARGQPGVMGFPG---PKGANGEPGKAGEKGLPGAPGLRGLPGK 565

Query: 773  RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 832
             GE G  G PG  G  GE+G  G PG  G  GLPG PG PG  G+ GDQG  GE G PGL
Sbjct: 566  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625

Query: 833  KGDRGEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGD---PGLPGEPGLQGR 887
             G RGE+G  G  G PG  G   L  P   P  PG  GPKG  G    PG  G PGLQG 
Sbjct: 626  VGPRGERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGM 682

Query: 888  PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947
            PGE G  G  GP G +G  G  G  GA G  G  G  G  GP GP G+ G  G  G PG 
Sbjct: 683  PGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGP 742

Query: 948  DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAA 1006
             G  G +GA GE G  GP GP G  G PG  G PG KG+ GE G +G  G PGP G   A
Sbjct: 743  AGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGA 802

Query: 1007 CGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSR 1065
             G          G   V G +GA G  G PG+ G PG  G  GPPG +G PG  G PG  
Sbjct: 803  PGPQ--------GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854

Query: 1066 GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLP 1125
            G  G  G +G +G  G  G PG +GP G PG      PGD      +     PPGP GL 
Sbjct: 855  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKG--EPGDDGPSGAEG----PPGPQGLA 908

Query: 1126 G------LPGFKGDKGVPG------KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173
            G      LPG +G++G PG      +PG++G  G  G+ GPPG  GPPG+ GP G  G  
Sbjct: 909  GQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGRE 968

Query: 1174 GA---------DGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224
            G+         DG  G KGD+G  G    +G PG PGPPG+ G AG  G  G +G  G +
Sbjct: 969  GSPGADGPPGRDGAAGVKGDRGETGA---VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQ 1025

Query: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDS 1284
            GP GP GP+G  GI G +G  G  G+ G PGE G  G  G  G +G  GPP   G +GD 
Sbjct: 1026 GPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP---GPSGDQ 1082

Query: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP 1344
            GA GP G SG  G PG  G  GKDG  G  GP GP GPRG  G+ G  G PG PGP G P
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1142

Query: 1345 GQKGSKGENGSPGLP----GFLGPRGPPGEP 1371
            G  G       PG+       LGPR    +P
Sbjct: 1143 GPPG-------PGIDMSAFAGLGPREKGPDP 1166



 Score =  145 bits (365), Expect = 4e-34
 Identities = 92/242 (38%), Positives = 109/242 (45%), Gaps = 20/242 (8%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPP----TPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGL 494
            P GP     +T P   P  +  P     PG +    +K        G++GE G  G  G 
Sbjct: 949  PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK--------GDRGETGAVGAPGA 1000

Query: 495  PGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPG 554
            PGP G  G  GP G  G +GE G  G      G  G  G+ G+ GP G  G KG  GEPG
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQG----PMGPSGPAGARGIQGPQGPRGDKGEAGEPG 1056

Query: 555  ELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPG 614
            E G  G  G  G++G  GPPG  G  G  G  G  G RG  G  G  G+ G +G PG  G
Sbjct: 1057 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIG 1116

Query: 615  DTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP----RGHQGA 670
              G +GR G +G AGP G  G  GP GPPG    +    GL   +  P P    R  Q A
Sbjct: 1117 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1176

Query: 671  PG 672
             G
Sbjct: 1177 GG 1178


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  878 bits (2268), Expect = 0.0
 Identities = 539/1222 (44%), Positives = 613/1222 (50%), Gaps = 185/1222 (15%)

Query: 483  KGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-------GP------------ 523
            +G  G  GP GL GP G  G  GPVG PG +G  G  G+       GP            
Sbjct: 398  EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 457

Query: 524  FGQGEKG--------------EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP------G 563
             G G+KG              ++  L L GPP   G  G  G PG LG+PG P      G
Sbjct: 458  SGGGDKGPVVAAQEAQAQAILQQARLALRGPP---GPMGYTGRPGPLGQPGSPGLKGESG 514

Query: 564  EVGMRGPQGPPGLPGPP---GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620
            ++G +GP+GP GL GPP   GR G  G  G RG  G  G KG+RG DG PG PG+ G +G
Sbjct: 515  DLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG 574

Query: 621  RPGPSGVAGP---QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGAR 677
              G  G+ GP    GE+GD G  GP G+PG               GPRG  G  GPPG  
Sbjct: 575  DTGAQGLPGPPGEDGERGDDGEIGPRGLPGE-------------SGPRGLLGPKGPPGIP 621

Query: 678  GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP---PGPGGSPGLP 734
            GP G  G DGP G +G  G +G+ GPPG  G  G QG PGP G  GP    GP G PGLP
Sbjct: 622  GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 681

Query: 735  GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLA 794
            G  G  G PG PG  GPPG  G  GP GP G  G PG RG  G+ G  GL+G  GE+G  
Sbjct: 682  GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED 741

Query: 795  GRPGEKGEAGLP---GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLP 851
            G PG KG+ G+    G  G PG RGE G +G KG  G  G  G  G  GE G  G PGLP
Sbjct: 742  GFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 801

Query: 852  GTTSLFTPHPRMPGEQGPKGEKGDPGLPGEP------GLQGRPGELGPQGPTGPPGAKGQ 905
            G           PG QGPKG  G PG PG        GL G+ G  G +GPTGP G +G 
Sbjct: 802  G----------YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP 851

Query: 906  EGA---------------HGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950
             GA               HG PG  G PG  G  G PGP GPPG  G  GL G PG+ GE
Sbjct: 852  RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGE 911

Query: 951  RGEKGAAGEEGSPGPVGPR---------GDPGAPGLPGPPGK----GKDGEPGLRGSPGL 997
             G +G  G  G PG VGP+         G+ G PG PGPPG+    G  G+ G +G PG 
Sbjct: 912  VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 998  PGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057
            PG  G     G +RG            G+RG PG  G PG +G+   G +GPPGP+G PG
Sbjct: 972  PGAPGKDGPAG-LRG----------FPGERGLPGTAGGPGLKGNE--GPSGPPGPAGSPG 1018

Query: 1058 DKGSPGSR---GLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            ++G+ GS    G PG PGPQGP G  G  G PGE+GP G  G   +  P  +        
Sbjct: 1019 ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL-------- 1070

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
                PGP G PG+ G  GDKG  G PG++GT+G KGE GP   PGPPG  GP G  G  G
Sbjct: 1071 ----PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP---PGPPGPIGPVGQPGAAG 1123

Query: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
            ADGE G +G QGH G  G  G  G  GPPG  G+ G  GP G +G  G  GP GP GP  
Sbjct: 1124 ADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP-- 1181

Query: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294
             PG  G  G  G DG  GPPG  G  G PG  G  G  G PG +   G+ G  GPRGE G
Sbjct: 1182 -PGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQ---GEPGVKGPRGERG 1237

Query: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354
              G  GQ G PG  G  GPTG  GP+G  GP G  G PG PGE GP G  G KG +GE+G
Sbjct: 1238 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDG 1297

Query: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP---GIKGDKGPPGGKG 1411
             PG PG  GP G  G PG  G  G  G PG  G  G KG +GDP   G  G  GP G  G
Sbjct: 1298 EPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAG 1357

Query: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471
              G PG  G +G  G +G QG PG  G  GPPGP G PG PGLRG++ +           
Sbjct: 1358 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAK---------- 1407

Query: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 1531
             G++    L  L+   PP      QG  G  G PG  G PG+ G MG PG  G  G  GP
Sbjct: 1408 -GEKGHPGLIGLIG--PP----GEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1460

Query: 1532 SGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP---------GIPG 1582
             G  GP G +GAKG  G PG G +GE G  G PG PG PG     LP          + G
Sbjct: 1461 PGLPGPAGPKGAKGATG-PG-GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1518

Query: 1583 ----PQGETGPAGHPGLPGPPG 1600
                 + E  P G  G PG PG
Sbjct: 1519 SRLMQEDEAIPTG--GAPGSPG 1538



 Score =  811 bits (2094), Expect = 0.0
 Identities = 561/1489 (37%), Positives = 686/1489 (46%), Gaps = 221/1489 (14%)

Query: 281  TEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAV 340
            T  +FP G P +++ +T  R R   +     +  +     + Q+ + L    + +  +  
Sbjct: 72   TRQLFPGGFPKDFSLLTVVRTRPGLQAP---LLTLYSAQGVRQLGLELGRPVRFLYEDQT 128

Query: 341  GAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCA--LVQTLPIEERENIDI 398
            G  +   + VFRG     L D  WH++A++++ Q+V+L +DC   + + LP   R  +D 
Sbjct: 129  GRPQPPSQPVFRGL---SLADGKWHRVAVAVKGQSVTLIVDCKKRVTRPLPRSARPVLDT 185

Query: 399  QGKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQ 458
             G  + G R+ D    + D+Q + I    + A     C+     C+     E P    P 
Sbjct: 186  HGVIIFGARILDEEVFEGDVQELAIVPGVQAAY--ESCEQKELECEGGQ-RERPQNQQPH 242

Query: 459  RPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG-----APGPK 513
            R      +Q   L       P  +  E           P  D+   G         PG +
Sbjct: 243  RAQRSPQQQPSRLHRPQNQEPQSQPTESLY---YDYEPPYYDVMTTGTTPDYQDPTPGEE 299

Query: 514  GEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGP 573
             E  +  + P  + E+ +     L  PP  D     R +  E GE G         P+GP
Sbjct: 300  EEILESSLLPPLEEEQTD-----LQVPPTAD-----RFQAEEYGEGGTDP------PEGP 343

Query: 574  PGLPGPPG-------RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSG 626
                   G        +G P L  E    G     G RGL G  G+P        PG   
Sbjct: 344  YDYTYGYGDDYREETELG-PALSAETAHSGAAAH-GPRGLKGEKGEPAVL----EPGML- 396

Query: 627  VAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRD 686
            V GP G +G  G  GPPG+             QG PGP G  G  GPPG  G  G +G  
Sbjct: 397  VEGPPGPEGPAGLIGPPGI-------------QGNPGPVGDPGERGPPGRAGLPGSDGAP 443

Query: 687  GPPGLQGLRGKK-----GDMGPPGIP-----------GLLGLQGPPGPPGVPGPPGPGGS 730
            GPPG   +   +     GD GP                 L L+GPPGP G  G PGP G 
Sbjct: 444  GPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQ 503

Query: 731  PGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGE 790
            PG PG  G  G  GP GP GP G     GPPG  G +G  G  G  G+PG PG++G+ G 
Sbjct: 504  PGSPGLKGESGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 560

Query: 791  QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGL 850
             GL G PGEKG  G  GA G PG  GE G++G+ GE+G  GL G+ G +G  GP GPPG+
Sbjct: 561  DGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 620

Query: 851  PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG---PQGPTGPPGAKGQEG 907
            PG   +      M G QGPKG  G  G PG PG QG PG  G   PQG  GP G KG +G
Sbjct: 621  PGPPGV----RGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG 676

Query: 908  AHGAPGAAGNPGAPGHVGAPGP---------SGPPGSVGAPGLRGTPGKDG--------- 949
              G PG  G+ G PGH G  GP         SGP G +G PG RG  G DG         
Sbjct: 677  KPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKG 736

Query: 950  ------------------ERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDG 987
                              +RGE G  G  G  GP GP+G  G  G PGPPG    KGK G
Sbjct: 737  EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 796

Query: 988  EPGLRGSPGLPGPLGTKAACGKVRGS-ENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-- 1044
             PGL G PG  GP G+    G    S E  A G     G RG  G  G  G RG  G   
Sbjct: 797  VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 856

Query: 1045 -----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPGNPGERG------ 1090
                 G +G  GP GPPG++G PG +G  GFPGP+GP G   +DG PG+PG+RG      
Sbjct: 857  KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 916

Query: 1091 ---PPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF------KGDKGVPGKPG 1141
               PPG PG+              +  +  PPGPPG  GLPG       KGD G PG PG
Sbjct: 917  KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976

Query: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201
            ++G  G +G  G  GLPG  G  G +G++G  G  G  G  G++G  G  G +GPPG PG
Sbjct: 977  KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036

Query: 1202 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI------------------PGEEG 1243
            P G  G AG  G PG +G  G  G  G QGP GLPG                   PG++G
Sbjct: 1037 PQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096

Query: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG---------PRGESG 1294
             +G  G+ GPPG PG  G  G PG  GA G PG +G  G  GA G         P G  G
Sbjct: 1097 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156

Query: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQKGSKG 1351
              GLPG  G  G+ GD GP GP GP GPRGP G NG+ G  G PG  G    PG+KG  G
Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216

Query: 1352 ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411
            E+GSPG+ G  G +GP GE GEKG   + G PG+PG PG KG  GD G KG+ GP G  G
Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1273

Query: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE-----SPSMETLRR 1466
             PG PG  G +G  G  G +G  GE G  G PGP G+ G PG  G+     SP  E    
Sbjct: 1274 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR-- 1331

Query: 1467 LIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG 1526
              Q   G + +        +  P       G  GP G PG DGL G  G +G+ GRPG  
Sbjct: 1332 --QGGKGAKGDPGAIGAPGKTGPV------GPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383

Query: 1527 GLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGPQG 1585
            G  GP GP+GP G  G +GD GA     +GE G PG+ G  G PG   + G  G+PGPQG
Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDAGA-----KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1438

Query: 1586 ETGPAGHPGLP---------GPPGPPGQCDPSQCAYFASLAARPGNVKG 1625
              G  G  G+P         GPPG PG   P      A  A  PG  KG
Sbjct: 1439 SPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG----AKGATGPGGPKG 1483



 Score =  795 bits (2052), Expect = 0.0
 Identities = 465/1053 (44%), Positives = 539/1053 (51%), Gaps = 109/1053 (10%)

Query: 454  PPPPQRPPTPGSE-QIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            P P  +P +PG + + G L       P G +G  G+ GP G  G +G  GA G  G PG 
Sbjct: 498  PGPLGQPGSPGLKGESGDLG------PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 551

Query: 513  KGEKGDVGIG-----PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGM 567
             G KGD G       P  +G +G+ G+ GLPGPPG DG    RG+ GE+G  GLPGE G 
Sbjct: 552  PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGE---RGDDGEIGPRGLPGESGP 608

Query: 568  RG---PQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGP 624
            RG   P+GPPG+PGPPG  G  G QG +G  G +GE G       PG+ G  G QG PGP
Sbjct: 609  RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP------PGQQGTPGTQGLPGP 662

Query: 625  SGVAGPQGEKGDVGPAGPPGVPGS--------VVQQEGLKGEQGAPGPRGHQGAPGPPGA 676
             G  GP GEKG  G  G PG+PGS             G KG QG  GP+G  G PGP G 
Sbjct: 663  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722

Query: 677  RGPIG---------PEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP------------ 715
            +G  G          +G DG PG +G  G KGD G  G+PG  G  GP            
Sbjct: 723  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782

Query: 716  PGPPGVPGPPGPGGSPGLPG---------EIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT 766
            PGPPG+ G  G  G PGLPG          +GFPG PG  G  G  G  G +GP G  G 
Sbjct: 783  PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGP 842

Query: 767  KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 826
             G  G+RG  G  GK G +G  G  G  G PGE+G  G  G  GFPG +G  G  G+ G 
Sbjct: 843  TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 902

Query: 827  LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 886
             G PG +G+ G +G+ GP GPPG+ G            GE GP GE+G PG PG PG QG
Sbjct: 903  PGHPGQRGEVGFQGKTGPPGPPGVVGPQGA-------AGETGPMGERGHPGPPGPPGEQG 955

Query: 887  RPGELGPQGPTG---PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRG 943
             PG  G +G  G   PPGA G++G  G  G  G  G PG  G PG  G  G  G PG  G
Sbjct: 956  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015

Query: 944  TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLG 1002
            +PG+ G  G  G  G  G PGP GP G  G  G+PG  G  G  G  G++G  GLPGP G
Sbjct: 1016 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 1075

Query: 1003 TKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGS 1061
                 G+               GD+G  G PG  G++G+ G  G  GPPGP GP G  G+
Sbjct: 1076 PPGVAGE--------------DGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGA 1121

Query: 1062 PGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGP 1121
             G+ G PG  GPQG  G  G  G  G  GPPG  GL  L  P        DV      GP
Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDV------GP 1175

Query: 1122 PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQ 1181
             G PG PG +G  G  G  G +G  G  G  GPPG  G PG +G  G QGE G  G  G+
Sbjct: 1176 MGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE 1235

Query: 1182 KGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGE 1241
            +G++G  G PG  GPPG  GP G DG  G  GP G  G P   GPPG  GP G  G  G+
Sbjct: 1236 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP---GPPGEGGPRGQDGAKGD 1292

Query: 1242 EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ 1301
             G+   DG+PG PG PG  GE G PGP G RGP G  G  G  G  G +G+ GA+G PG+
Sbjct: 1293 RGE---DGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1349

Query: 1302 EGLPGKDGDTGPTGPQGPQ------GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355
             G  G  G  G  GP G +      G +G PG  G  G PG  GP G PG +G  G  G 
Sbjct: 1350 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409

Query: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD 1415
             G PG +G  GPPGE GEK   G  G+PG  G PG KGE G PG  G  GP G  G PG 
Sbjct: 1410 KGHPGLIGLIGPPGEQGEK---GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1466

Query: 1416 PGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
             G  G KG TG  GP+G  G  GP G PGPPG+
Sbjct: 1467 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1499



 Score =  540 bits (1391), Expect = e-153
 Identities = 311/694 (44%), Positives = 358/694 (51%), Gaps = 87/694 (12%)

Query: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPM---GLPGPKGDIGAIGPVG 508
            P  P  QR P   + + G   T     P G  GE G+ GP    G PGPKG  G  G  G
Sbjct: 842  PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDG 901

Query: 509  APGPKGEKGDVG-------------IGPFG----QGEKGEKGSLGLPGPPGRDGSKGMRG 551
             PG  G++G+VG             +GP G     G  GE+G  G PGPPG  G  G  G
Sbjct: 902  LPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG 961

Query: 552  EPGELGEPGLPGEVGMRGPQGPPGLPGP---PGRVGAPGLQGERGEK------GTRGEKG 602
            + G  G+PG PG  G  GP G  G PG    PG  G PGL+G  G        G+ GE+G
Sbjct: 962  KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG 1021

Query: 603  ERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA------GPPGVPG-----SVVQ 651
              G  G  G PG  G QG PG +G  G  GEKG +GP       GP G+PG      V  
Sbjct: 1022 AAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG 1081

Query: 652  QEGLKGEQGAPGP------RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705
            ++G KGE G PG       +G  G PGPPG  GP+G  G  G  G  G RG +G  G  G
Sbjct: 1082 EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1141

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI---GFPGKPGPPGPTGPPGKDGPNGPPG 762
              G  G  GPPGP G+ G PGP G  G  G++   G PG PGP GP GP G DGP GPPG
Sbjct: 1142 DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1201

Query: 763  PPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG 822
              G  G PGE+GE G  G PG++GE G +G  G  GEKGE+G PG PG PG +G  GD G
Sbjct: 1202 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDG 1261

Query: 823  EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEP 882
             KG  G  G  GD G  GE GP G  G               G++G  GE G PG PG  
Sbjct: 1262 PKGNPGPVGFPGDPGPPGEGGPRGQDG-------------AKGDRGEDGEPGQPGSPGPT 1308

Query: 883  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942
            G  G PG LG +GP G PG++G++G  GA G  G  GAPG  G  GP+GP G  G  GLR
Sbjct: 1309 GENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLR 1368

Query: 943  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPL 1001
            G PG  G++G  GA G+ G PGPVGP   PG PGL G  G KG+ G PGL G  G PG  
Sbjct: 1369 GLPGSVGQQGRPGATGQAGPPGPVGP---PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQ 1425

Query: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKG 1060
            G                     KGDRG PG  GSPG +G+ GI G +GP GP GPPG  G
Sbjct: 1426 GE--------------------KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1465

Query: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGK 1094
              G +G  G  GP GP G  G  G PG  GPPG+
Sbjct: 1466 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1499



 Score =  458 bits (1178), Expect = e-128
 Identities = 286/667 (42%), Positives = 327/667 (49%), Gaps = 79/667 (11%)

Query: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511
            PP PP    P   + + G +       P G  GE G+ G  G  G KGD    GP GAPG
Sbjct: 920  PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGD---PGPPGAPG 976

Query: 512  PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571
              G  G        +G  GE+G  G  G PG  G++G  G PG  G PG  G  G  GP 
Sbjct: 977  KDGPAG-------LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI 1029

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLD---------GFPGKPGDTGQQGRP 622
            GPPG PGP G  GA G +G  GEKG  G  G  G+          G PG  G+ G +G  
Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 623  GPSGVAGPQGEKGDVGPAGPPGVPGSVVQ--QEGLKGEQGAPGPRGHQGAPGPPGAR--- 677
            G  G  G +G KG+ GP GPPG  G V Q    G  GE GA GP+GH GA G  G R   
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149

Query: 678  GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI 737
            GP GP G  G PG  G +G+ GD+GP G PG  G +GP GP G  GP GP   PG  G +
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP---PGGVGNL 1206

Query: 738  GFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 797
            G PG+ G PG +G PG  G  G  GP G +GE GE G+ G PG PG +G  G+ G  G P
Sbjct: 1207 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266

Query: 798  GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 857
            G  G  G PG PG  G RG+ G +G++GE G PG  G  G  GE GP GP G  G     
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG-- 1324

Query: 858  TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 917
               P   G QG KG KGDPG  G P   G+ G +GP GP G PG  G  G  G+ G  G 
Sbjct: 1325 --SPGSEGRQGGKGAKGDPGAIGAP---GKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGR 1379

Query: 918  PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL 977
            PGA G  G PGP GPP   G PGLRG  G  GE+G  G  G  G PG  G +GD G PG 
Sbjct: 1380 PGATGQAGPPGPVGPP---GLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP 1436

Query: 978  PGPPG-KGKDGEPGLR------GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAP 1030
             G PG KG+ G PG        G PGLPGP G K                       GA 
Sbjct: 1437 QGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPK-----------------------GAK 1473

Query: 1031 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGR----------D 1080
            G  G  G +G+   GV GPPG  GPPG+   P    +P          R           
Sbjct: 1474 GATGPGGPKGEK--GVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG 1531

Query: 1081 GAPGNPG 1087
            GAPG+PG
Sbjct: 1532 GAPGSPG 1538



 Score =  442 bits (1137), Expect = e-123
 Identities = 276/662 (41%), Positives = 320/662 (48%), Gaps = 75/662 (11%)

Query: 1013 SENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG--- 1069
            S   A  G    G RG  G  G P    +PG+ V GPPGP GP G  G PG +G PG   
Sbjct: 365  SAETAHSGAAAHGPRGLKGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVG 423

Query: 1070 FPGPQGPAGRDGAPGNPGERGPPGK----------------PGLSSLLSPGDINLLAKDV 1113
             PG +GP GR G PG+ G  GPPG                 P +++  +     L    +
Sbjct: 424  DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 483

Query: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG---SQ 1170
                PPGP G  G PG  G  G PG  G  G  G +G  GP GL GPPG AG +G   + 
Sbjct: 484  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 543

Query: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGN---------PGPPGADGIAGAAGPPGIQGSP 1221
            G RG  G+ G KGD+G  G+PG  G  G+         PGPPG DG  G  G  G +G P
Sbjct: 544  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 603

Query: 1222 GKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---RGPPGFK 1278
            G+ GP G  GP G PGIPG  G  G DG  GP G  G  GEPG PG +G    +G PG +
Sbjct: 604  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 663

Query: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 1338
            G  G  G  GP+G+ G  G+PG +G PG  G  GP G +G QGP GP G  G PG  G  
Sbjct: 664  GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 723

Query: 1339 GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 1398
            G  G  G KG KGE G  G PGF G  G  G+ GE GVPG  G  G  G  G  G  GDP
Sbjct: 724  GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 783

Query: 1399 GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 1458
            G  G  G  G  G PG PG PG +G  G +G  G PG +G  G  G  G+ G  G RG  
Sbjct: 784  GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERG-- 841

Query: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 1518
            P+    +R  +   GK               +  K + G  GP GPPG+ GLPG  GP G
Sbjct: 842  PTGPRGQRGPRGATGK---------------SGAKGTSGGDGPHGPPGERGLPGPQGPNG 886

Query: 1519 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKD-- 1575
             PG         P GP GP G+ G  G PG  G VG +G+ GPPG PG  G  G A +  
Sbjct: 887  FPG---------PKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937

Query: 1576 -----GLPGIPGPQGE------TGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVK 1624
                 G PG PGP GE       G  G  G PGPPG PG+  P+    F      PG   
Sbjct: 938  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997

Query: 1625 GP 1626
            GP
Sbjct: 998  GP 999



 Score =  398 bits (1023), Expect = e-110
 Identities = 244/547 (44%), Positives = 277/547 (50%), Gaps = 60/547 (10%)

Query: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAP 510
            PP  P PQ PP    E+             G  GE G  GP G  G +G +G  GP G P
Sbjct: 1031 PPGRPGPQGPPGAAGEK-------------GVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 1077

Query: 511  GPKGEKGDVG-IGPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL---PGEV 565
            G  GE GD G +G  GQ G KG KG  G PGPPG  G  G  G  G  GEPG     G  
Sbjct: 1078 GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF 1137

Query: 566  GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625
            G +G +G  G  GPPG +G  GL G  GEKG  G+ G        G PG  G +G  GP+
Sbjct: 1138 GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM------GPPGPPGPRGPAGPN 1191

Query: 626  GVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGR 685
            G  GPQG  G VG  GPPG       ++G  GE G+PG +G  G  GP G RG  G  G+
Sbjct: 1192 GADGPQGPPGGVGNLGPPG-------EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244

Query: 686  DGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGP 745
             G PG  G +G  GD GP G PG +G  G PGPPG  GP G  G+ G  GE G PG+PG 
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS 1304

Query: 746  PGPT------GPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE 799
            PGPT      GP GK GP G PG  G +G  G +G+ G  G PG  G +G  G AG+PG 
Sbjct: 1305 PGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGP 1364

Query: 800  KGEAGLPGA---PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856
             G  GLPG+    G PG  G+ G  G  G  GLPGL+GD G KGE G  G  GL G    
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGP--- 1421

Query: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR---PGELGPQGPTGPPGAKGQEGAHGAPG 913
                   PGEQG KG++G PG  G PG +G    PG  GP GP GPPG  G  G  GA G
Sbjct: 1422 -------PGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1474

Query: 914  AAGNPGAP----GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR 969
            A G PG P    G  G PG  GPPG V  P     P K     +     +E    P G  
Sbjct: 1475 ATG-PGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTG-- 1531

Query: 970  GDPGAPG 976
            G PG+PG
Sbjct: 1532 GAPGSPG 1538


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  866 bits (2238), Expect = 0.0
 Identities = 528/1200 (44%), Positives = 587/1200 (48%), Gaps = 160/1200 (13%)

Query: 464  GSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG- 522
            GSE     +T     P G+ G  G  GP G PG  G  G  G  G PGP G  G  G+G 
Sbjct: 98   GSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGG 157

Query: 523  ------PFGQGEK-----------GEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEV 565
                   +G  EK           G  G  GLPGPPG  G +G +G PGE GEPG  G +
Sbjct: 158  NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM 217

Query: 566  GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPS 625
            G RGP      PGPPG+ G  G  G+ G  G RG  G +G  G PG  G  G +G  G S
Sbjct: 218  GPRGP------PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFS 271

Query: 626  GVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPG---PRGHQGAPGPPGARGPIGP 682
            G+    G KGD GPAGP G PGS        GE GAPG   PRG  G  G PGA GP G 
Sbjct: 272  GL---DGAKGDAGPAGPKGEPGS-------PGENGAPGQMGPRGLPGERGRPGAPGPAGA 321

Query: 683  EGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGK 742
             G DG  G  G  G  G  GPPG PG +G +G  GP G  G  GP G           G+
Sbjct: 322  RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG---------VRGE 372

Query: 743  PGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGE 802
            PGPPGP G  G  G  G  G PG KG  G  G  G PG PG RG  G QG  G PG KG 
Sbjct: 373  PGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN 432

Query: 803  AGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL-----F 857
            +G PGAPG  G  G KG+ G  G  G PG  G+ G++G  G  GP GLPG          
Sbjct: 433  SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGS 492

Query: 858  TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 917
               P   G  GPKG  G+ G PG  G +G PGE G  G  G PGAKG  G+ G+PG  G 
Sbjct: 493  RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 918  PGAPGHVGA---PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP---VGPRGD 971
             G PG  G    PGP GPPG+ G  G+ G PG  G  GE G AGE G PGP   VGP G 
Sbjct: 553  TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK 612

Query: 972  PGAPGLPGPPGK----GKDGEPGLRGSPG---LPGPLGTKAACGKVRGSENCALGGQCVK 1024
             G  G  GPPG     G+ GE G  GSPG   LPGP G     GK         G Q V 
Sbjct: 613  DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP--------GEQGVP 664

Query: 1025 GDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGP------PGDKGSPGSRGLPGFPGPQGPA 1077
            GD GAPG  G+ G RG PG  GV GPPGP+GP      PG+ G+ G  G PG PG QG  
Sbjct: 665  GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724

Query: 1078 GRDGAPGNPGERGPPGKPGLSSLLSP-GDINLLAKDVCNDC--PPGPPGLPGLPGFKGDK 1134
            G  G PG  G  G PG  G      P G      KD       P GPPG  G PG KG+ 
Sbjct: 725  GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784

Query: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFM 1194
            G  G  G  G  G  G+ G PG PGP G AGP G+ G+ GA GE G  G +G  G PG  
Sbjct: 785  GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 1195 GPPGNPGP------PGADGIAGAAGPPGIQGSP---GKEGPPGPQGPSGLPGIPGEEGKE 1245
            GP G PGP      PGA G  G+AGPPG  G P   G+ GPPGP G +G PG PG  GKE
Sbjct: 845  GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904

Query: 1246 GRD---GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR---GESGAMGLP 1299
            G     G+ GP G PG+ G PG PGP G +G PG  G  G  G PGP+   G+ G +GLP
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 1300 GQE------GLPGKDGDTGPTGPQGPQGPRGPPGKNGSP---GSPGEPGPSGTPGQKGSK 1350
            GQ       GLPG  G+ G  GP G  G RGPPG  G P   G PGE G  G PG +GS 
Sbjct: 965  GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024

Query: 1351 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGK 1410
            G +GSPG  G  G  GP G PG  G PG  G  G  G+ G +GE G  G  G  GP G +
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084

Query: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470
            G  G  G  G KG TG  G +G+ G  G  G  GPPG PG PG +G S            
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS------------ 1132

Query: 1471 ELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEG 1530
                                    + G  GP GPPG           G PG+ G  GL G
Sbjct: 1133 -----------------------GASGPAGPRGPPGS---------AGAPGKDGLNGLPG 1160

Query: 1531 PSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEP--GYAKDGLPGIPGPQGETG 1588
            P GP GP+G  G  G  G P        GPPG PG PG P  G+    LP  P  +   G
Sbjct: 1161 PIGPPGPRGRTGDAGPVGPP--------GPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212



 Score =  851 bits (2199), Expect = 0.0
 Identities = 509/1186 (42%), Positives = 580/1186 (48%), Gaps = 179/1186 (15%)

Query: 559  PGLPGEVGMRGPQGPPGLPGPPGR--VGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDT 616
            PG     G   P  P G   P  +   G  G +G+ G +G RG  G  G DG PG+PG  
Sbjct: 82   PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141

Query: 617  GQQGRPGPSGVAGPQGE-------------------KGDVGPAGPPGVPGSVVQQEGLKG 657
            G  G PGP G  G  G                     G +GP+GP G+PG          
Sbjct: 142  GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGP--------- 192

Query: 658  EQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPG 717
              GAPGP+G QG PG PG  G  GP G  GPPG  G  G  G+ G PG PG    +GPPG
Sbjct: 193  -PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE---RGPPG 248

Query: 718  PPGVPGPPGPGGSPGLPGEIGFPG------KPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771
            P G  G PG  G PG+ G  GF G        GP GP G PG  G NG PG  G +G PG
Sbjct: 249  PQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308

Query: 772  ERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 831
            ERG  G PG  G RG  G  G AG PG  G AG PG PG  G +GE G QG +G  G  G
Sbjct: 309  ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368

Query: 832  LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891
            ++G+ G  G AG AGP G PG            G+ G KG  G PG+ G PG  G  G  
Sbjct: 369  VRGEPGPPGPAGAAGPAGNPGAD----------GQPGAKGANGAPGIAGAPGFPGARGPS 418

Query: 892  GPQGPTGPPGAKGQEGAHGAPGAAGNPGA---PGHVGAPGPSGP---------------- 932
            GPQGP GPPG KG  G  GAPG+ G+ GA   PG VG  GP GP                
Sbjct: 419  GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478

Query: 933  -----PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG-------------- 973
                 PG  G PG RG PG DG  G KG AGE GSPGP GP+G PG              
Sbjct: 479  GLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAK 538

Query: 974  ----APGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVK-GDR 1027
                +PG PGP GK G  G  G  G PG PGP G +   G +         G+  K G+R
Sbjct: 539  GLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER 598

Query: 1028 GAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNP 1086
            G PG PG+ G  G  G  G  GPPGP+GP G++G  G  G PGF G  GPAG  G  G P
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658

Query: 1087 GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG----- 1141
            GE+G PG  G                      PGP G  G  GF G++GV G PG     
Sbjct: 659  GEQGVPGDLGA---------------------PGPSGARGERGFPGERGVQGPPGPAGPR 697

Query: 1142 ----REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP 1197
                  G +G KG+AG PG PG  G  G QG  GERGA G  G KGD+G  G  G  G P
Sbjct: 698  GANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSP 757

Query: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP 1257
            G  G  G  G  G  GP G  G  G+ GP GP GP+G  G PG+ G+      PGPPG  
Sbjct: 758  GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGE------PGPPGPA 811

Query: 1258 GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGA------MGLPGQEGLPGKDGDT 1311
            G AG PG  G  GA+G PG  G  GD+G PGP G +G       +G PG +G  G  G  
Sbjct: 812  GFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP 871

Query: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371
            G TG  G  G  GPPG +G+ G PG PGP+G  G KG +GE G  G PG +GP GPPG  
Sbjct: 872  GATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPA 931

Query: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431
            GEKG PG +G  G PG PG +G  G  G+ G    PG +G+ G PG+PG  G  G  GP 
Sbjct: 932  GEKGSPGADGPAGAPGTPGPQGIAGQRGVVG---LPGQRGERGFPGLPGPSGEPGKQGPS 988

Query: 1432 GLPGENGPVGPPGPPGQPGFPGLRGE--SPSMETL--RRLIQEELGKQLETRLAYLLAQM 1487
            G  GE GP GP GPPG  G PG  G   +P  E    R       G + ET  A      
Sbjct: 989  GASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA------ 1042

Query: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDP 1547
             P     + G PGP GP GK G  G  GP G  G  G  G  GP+GP GP+G++G  G+ 
Sbjct: 1043 GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQ 1102

Query: 1548 GAPGV----GLRGEMGPPGIPGQPGE---------------PGYA----KDGLPGI---- 1580
            G  G+    G  G  GPPG PG PGE               PG A    KDGL G+    
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162

Query: 1581 --PGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVK 1624
              PGP+G TG AG  G PGPPGPPG   P    +  S   +P   K
Sbjct: 1163 GPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEK 1208



 Score =  836 bits (2160), Expect = 0.0
 Identities = 484/1078 (44%), Positives = 557/1078 (51%), Gaps = 104/1078 (9%)

Query: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511
            P PP P  PP P      F   ++        G + V GPMG  GP+   G  GP GAPG
Sbjct: 141  PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPR---GLPGPPGAPG 197

Query: 512  PKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571
            P+G +G  G  P   G  G  G  G PGPPG++G  G  G+PG  GE G PG  G RG  
Sbjct: 198  PQGFQGPPG-EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256

Query: 572  GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL---DGFPGK------PGDTGQQGRP 622
            G  GLPG  G  G  GL G +G+ G  G KGE G    +G PG+      PG+ G+ G P
Sbjct: 257  GTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAP 316

Query: 623  GPS------GVAGPQGEKGDVGPAGPPGVPGSV-----VQQEGLKGEQGAPGPRGHQGAP 671
            GP+      G  G  G  G  GPAGPPG PG+V        +G +G +G  G RG  G P
Sbjct: 317  GPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376

Query: 672  GPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSP 731
            GP GA GP G  G DG PG +G  G  G  G PG PG  G  GP GP G PGP G  G P
Sbjct: 377  GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP 436

Query: 732  GLP---GEIGFPGKPGPPGPTGPP------------GKDGPNGPPGPPGTKGEPGER--- 773
            G P   G+ G  G+PGP G  GPP            G+ GP G PGPPG +G PG R   
Sbjct: 437  GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP 496

Query: 774  GEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLK 833
            G DG+ G  G  GE G  G AG  G  GEAG PG  G PG +G  G  G  G  G  G  
Sbjct: 497  GADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPP 556

Query: 834  GDRGEKGEAGPAGPPGLPGTTSLF-TPHPR-MPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891
            G  G+ G  GP GPPG  G   +   P P+   GE G  GE+G PG PG  G  G+ GE 
Sbjct: 557  GPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEA 616

Query: 892  GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGER 951
            G QGP GP G  G+ G  G  G+ G  G PG  G PG +G PG  G PG  G PG  G R
Sbjct: 617  GAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR 676

Query: 952  GEKGAAGE---EGSPGPVGPR------------GDPGAPGLPGPPG-KGKDGEPGLRGSP 995
            GE+G  GE   +G PGP GPR            GD GAPG PG  G  G  G PG RG+ 
Sbjct: 677  GERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 996  GLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSG 1054
            GLPGP G +   G  +G++    G     G RG  G  G PG  G PG  G +GP GP+G
Sbjct: 737  GLPGPKGDRGDAGP-KGAD----GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAG 791

Query: 1055 PPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS-PGDINLLAKDV 1113
            P G +G+PG RG PG PGP G AG  GA G PG +G PG  G       PG         
Sbjct: 792  PTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG--- 848

Query: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173
                PPGP G  G PG KG +G  G PG  G  G  G  GP   PGP G AGP G  G  
Sbjct: 849  ----PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGP---PGPSGNAGPPGPPGPA 901

Query: 1174 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 1233
            G +G  G +G+ G  G PG +GPPG PGP G  G  GA GP    G+PG  GP G  G  
Sbjct: 902  GKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGP---AGAPGTPGPQGIAGQR 958

Query: 1234 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 1293
            G+ G+PG+ G+ G  G PGP GEPGK G     G  G RGPP   G  G  G  GP GES
Sbjct: 959  GVVGLPGQRGERGFPGLPGPSGEPGKQGP---SGASGERGPP---GPMGPPGLAGPPGES 1012

Query: 1294 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGEN 1353
            G  G PG EG PG+DG  G  G +G  GP GPPG  G+PG+PG  GP+G  G +G  G  
Sbjct: 1013 GREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPA 1072

Query: 1354 GSPGLPGFLGPRGP------------PGEPGEKGVPGK------EGVPGKPGEPGFKGER 1395
            G  G  G +G RGP             GE G++G+ G       +G PG PG PG +G  
Sbjct: 1073 GPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132

Query: 1396 GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453
            G  G  G +GPPG  G PG  G+ G  G  G  GP+G  G+ GPVGPPGPPG PG PG
Sbjct: 1133 GASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPG 1190



 Score =  688 bits (1776), Expect = 0.0
 Identities = 416/934 (44%), Positives = 472/934 (50%), Gaps = 119/934 (12%)

Query: 459  RPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP---KGDIGAIGPVGAPGPKGE 515
            RP  PG    G       +  AG  G  G AGP G PG    KG+ G  GP G+ GP+G 
Sbjct: 312  RPGAPGPA--GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV 369

Query: 516  KGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPG 575
            +G+ G      G  G  G  G PG  G+ G+KG  G PG  G PG PG  G  GPQGP G
Sbjct: 370  RGEPG----PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG 425

Query: 576  LPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG---RPGPSGVAGPQG 632
             PGP G  G PG  G +G+ G +GE G  G+ G PG  G+ G++G    PGP+G+ GP G
Sbjct: 426  PPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG 485

Query: 633  EKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQ 692
            E+G  G  G PG  G V   +G  GE+G+PGP G +G+PG  G  G  G  G  G  G  
Sbjct: 486  ERGGPGSRGFPGADG-VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544

Query: 693  GLRGKKGDMGPPGIPGLLGLQGPPGPPG------VPGPPGPGGSPGLPGEIGFPGKPGPP 746
            G  G  G  GPPG  G  G  GPPGPPG      V G PGP G+ G PG+ G  G PGPP
Sbjct: 545  GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604

Query: 747  GPTGPPGKDGP---NGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEA 803
            G  GP GKDG     GPPGP G  GE GE+G  G PG  GL G  G  G AG+PGE+G  
Sbjct: 605  GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664

Query: 804  GLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE---------KGEAGPAGPPGLPGTT 854
            G  GAPG  G RGE+G  GE+G  G PG  G RG          KG+AG  G PG  G  
Sbjct: 665  GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724

Query: 855  SLFTPHPRMPGEQG------PKGEKGDPG------LPGEPGLQGRPGELGPQGPTGPPGA 902
             L      MPGE+G      PKG++GD G       PG+ G++G  G +GP GP G PG 
Sbjct: 725  GL----QGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780

Query: 903  KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 962
            KG+ G  G  G  G  GAPG  G PGP GP G  G PG  G PG  GE G+ GA G+ G 
Sbjct: 781  KGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGP 840

Query: 963  PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQC 1022
            PGP GP G PG  G  G PG       G RGS G PG  G   A G+V        G   
Sbjct: 841  PGPAGPAGPPGPIGNVGAPGA-----KGARGSAGPPGATGFPGAAGRV--------GPPG 887

Query: 1023 VKGDRGAPGIPGSPGSRGDPGI----------GVAGPPGPSGPPGDKGSPGS---RGLPG 1069
              G+ G PG PG  G  G  G           G  GPPGP GP G+KGSPG+    G PG
Sbjct: 888  PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947

Query: 1070 FPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDC--------PPGP 1121
             PGPQG AG+ G  G PG+RG  G PGL     PG      K   +          P GP
Sbjct: 948  TPGPQGIAGQRGVVGLPGQRGERGFPGL-----PGPSGEPGKQGPSGASGERGPPGPMGP 1002

Query: 1122 PGLPGLPGFKGDKGVPG---KPGREGTEGKKGE------AGPPGLPGPPGIAGPQGSQGE 1172
            PGL G PG  G +G PG    PGR+G+ G KG+      AGPPG PG PG  GP G  G+
Sbjct: 1003 PGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGK 1062

Query: 1173 RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGP 1232
             G  GE G  G  G  G  G  GP G  GP G  G  G  G  GI+G  G  G  GP GP
Sbjct: 1063 SGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGP 1122

Query: 1233 SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGE 1292
               PG PGE+G  G  G  GP G PG AG PG  G  G  GP          G PGPRG 
Sbjct: 1123 ---PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP---------IGPPGPRGR 1170

Query: 1293 SGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            +G  G              GP GP GP GP GPP
Sbjct: 1171 TGDAG------------PVGPPGPPGPPGPPGPP 1192



 Score =  488 bits (1257), Expect = e-137
 Identities = 294/649 (45%), Positives = 332/649 (51%), Gaps = 45/649 (6%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            P PP    P     + G       + PAGE+GE G AG  G  G  G  G  G  G PG 
Sbjct: 601  PGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGE 660

Query: 513  KGEKGDVGI-GPFG-QGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP 570
            +G  GD+G  GP G +GE+G  G  G+ GPPG  G +G  G PG  G  G  G  G  G 
Sbjct: 661  QGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGS 720

Query: 571  QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP 630
            QG PGL G PG  GA GL    G KG RG+ G +G DG PGK G  G  G  GP G AG 
Sbjct: 721  QGAPGLQGMPGERGAAGLP---GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGA 777

Query: 631  QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690
             G+KG+ GP+GP G  G+          +GAPG RG  G PGP G  GP G +G+ G  G
Sbjct: 778  PGDKGESGPSGPAGPTGA----------RGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827

Query: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTG 750
              G  G KGD GPPG  G  G  GP G  G PG  G  GS G PG  GFPG  G  GP G
Sbjct: 828  EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887

Query: 751  PPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG 810
            P G  GP GPPGP G +G  G RGE G  G+P   GE+G  G  G  GEKG  G  G  G
Sbjct: 888  PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP---GEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPK 870
             PG  G +G  G++G +GLPG +G+RG  G  GP+G PG  G +          GE+GP 
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSG-------ASGERGPP 997

Query: 871  GEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS 930
            G  G PGL G PG  GR G  G +G  G  G+ G +G  G  G AG PGAPG  GAPGP 
Sbjct: 998  GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV 1057

Query: 931  GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEP 989
            GP G  G    RG  G  G  G  G  G  G  GP GPRGD G  G  G  G KG  G  
Sbjct: 1058 GPAGKSGD---RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFS 1114

Query: 990  GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAG 1048
            GL+G PG PG  G           E    G     G RG PG  G+PG  G  G+ G  G
Sbjct: 1115 GLQGPPGPPGSPG-----------EQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 1049 PPGPSGPPGDKGSPGSRGLPGFPGPQGP--AGRDGA--PGNPGERGPPG 1093
            PPGP G  GD G  G  G PG PGP GP  AG D +  P  P E+   G
Sbjct: 1164 PPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212



 Score =  320 bits (819), Expect = 9e-87
 Identities = 192/455 (42%), Positives = 217/455 (47%), Gaps = 38/455 (8%)

Query: 448  VTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPV 507
            +T P  PP P   P    E          S PAG  G  G  G  G PGP G  G  GP 
Sbjct: 765  LTGPIGPPGPAGAPGDKGES-------GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP 817

Query: 508  GA---PGPKGEKGDVGI----GPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEP 559
            GA   PG KGE GD G     GP G  G  G  G +G  G PG  G++G  G PG  G P
Sbjct: 818  GADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFP 877

Query: 560  GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQ 619
            G  G VG  GP G  G PGPPG  G  G +G RGE G  G  GE G  G PG  G+ G  
Sbjct: 878  GAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937

Query: 620  GRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ-----------QEGLKGEQGAPGPRGHQ 668
            G  GP+G  G  G +G  G  G  G+PG   +           + G +G  GA G RG  
Sbjct: 938  GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP 997

Query: 669  GAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPG 728
            G  GPPG  GP G  GR+G PG +G  G+ G  G  G  G  G  GPPG PG PG PGP 
Sbjct: 998  GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV 1057

Query: 729  GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL---------- 778
            G  G  G+ G  G  GP GP GP G  GP GP GP G KGE GE+G+ G+          
Sbjct: 1058 GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQ 1117

Query: 779  --PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDR 836
              PG PG  GE G  G +G  G +G  G  GAPG  G+ G  G  G  G  G  G  G  
Sbjct: 1118 GPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPV 1177

Query: 837  GEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
            G  G  GP GPPG P     F+  P+ P E+   G
Sbjct: 1178 GPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDG 1212


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  865 bits (2236), Expect = 0.0
 Identities = 526/1226 (42%), Positives = 614/1226 (50%), Gaps = 142/1226 (11%)

Query: 443  CQVTVVTEPPPPPPPQRPP----TPGSEQIGFLKTINCSCPAGEKGEMG----VAGPMGL 494
            CQ  +    P  PP +  P    TPG     F +        G+KGE G    V G  G 
Sbjct: 76   CQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRK-----GQKGEPGLVPVVTGIRGR 130

Query: 495  PGPKGDIGAIGPVGAPGPKGEKGDVGIGPFG-QGEKGEKGSLGLPGPPGRDGSKGMRG-- 551
            PGP G  G+ GP G  GPKG  G  G  P G  GE G  G  G PGPPG     G  G  
Sbjct: 131  PGPAGPPGSQGPRGERGPKGRPGPRG--PQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLS 188

Query: 552  -----------EPGELG-EPGL-PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTR 598
                       E   LG + GL PG VG  GP+GP GL G  G  G  G  GE G+ G  
Sbjct: 189  RPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPM 248

Query: 599  GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGE 658
            G  G RG +G PGKPG+ G+ GR G  G  G  G  G  G  G PG+PG     +G +G 
Sbjct: 249  GPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL----KGHRGH 304

Query: 659  QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718
            +G  GP+G  GAPG  G  GP GP G  GP G +G+ G++G +GP G PG  G  G    
Sbjct: 305  KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHG---- 360

Query: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778
              +PG PGP G  G+PG  GFPG PG  G  GP G  GP GP G  G  G PG  G  GL
Sbjct: 361  --MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGL 418

Query: 779  PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
            PG  G  G  G +G  G PG  G  G  G PG PG +G  G QG +G+ G PG+ G +GE
Sbjct: 419  PGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGE 478

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGL---QGRPGELGPQG 895
             G  G  GP G+ G           PGE+G +G +GDPG  G PG    +G PG  G  G
Sbjct: 479  AGPKGEPGPHGIQGPIG-------PPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPG 531

Query: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955
              G PG KG +G  G  G++G  G+ G  G PG  G PG+ G  G  G  G +G+ G  G
Sbjct: 532  SDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLG 591

Query: 956  AAGEEGSPGP---VGPRGDPGAPGLPGPPGKGKD-GEPGLRGSPGLPGPLGTKAACGKVR 1011
            A GE+G PGP   +G RG PG+ GLPGP G   D G+PG  G+ G+PG  G     G+V 
Sbjct: 592  APGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVG 651

Query: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGF 1070
             S           G  G PG+ G  G +G PG  G  G PGP GPPG+ G PG +G+PG 
Sbjct: 652  PS-----------GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGD 700

Query: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLA---KDVCNDCP--------P 1119
            PG  GP G  G  GNPGERG PG  GL     PG+  +      D     P         
Sbjct: 701  PGAVGPLGPRGERGNPGERGEPGITGL-----PGEKGMAGGHGPDGPKGSPGPSGTPGDT 755

Query: 1120 GPPGLPGLPGF---------KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQ 1170
            GPPGL G+PG          KGD+G  G+ G EGT G  G  G PG  GPPG AGP G +
Sbjct: 756  GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815

Query: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGN---PGPPGADGIAGAAGPPGIQGSPGKEGPP 1227
            GE G  G VG  G +G+PG  G  GP G     GP G DG  G  G PG  G  G  G P
Sbjct: 816  GEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875

Query: 1228 GPQGPSGLPG------IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 1281
            GPQG +G PG      +PG +G  G  G PG  G PG AG  G PGP GA GP G  G  
Sbjct: 876  GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935

Query: 1282 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 1341
            G  G PG RG+ G+ G         + GD GP GP G  G +G PG++G PG  G PGP+
Sbjct: 936  GKEGPPGLRGDPGSHG---------RVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPA 986

Query: 1342 GTPGQK---GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 1398
            GT GQ+   G  G+ G  G+PG  GP G PG+ G  G  G +G PG  G PG  G  G+P
Sbjct: 987  GTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEP 1046

Query: 1399 GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 1458
               G +GP G  G PG  G  G +G  G  GP GLPG  G  G PGP G PG  G RG+ 
Sbjct: 1047 ---GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDP 1103

Query: 1459 PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 1518
             S                          + P      +G PGP GP G  G  G  G  G
Sbjct: 1104 GSR-----------------------GPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 1519 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-YAKDGL 1577
            + G  G  GL+G  GP GP GE+G+ G PG    G RG  GP G  G+ G PG     G 
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP--FGPRGPPGPVGPSGKEGNPGPLGPIGP 1198

Query: 1578 PGIPGPQGETGPAGHPGLPGPPGPPG 1603
            PG+ G  GE GP G PG PGPPGPPG
Sbjct: 1199 PGVRGSVGEAGPEGPPGEPGPPGPPG 1224



 Score =  842 bits (2175), Expect = 0.0
 Identities = 527/1262 (41%), Positives = 611/1262 (48%), Gaps = 232/1262 (18%)

Query: 511  GPKGEKGDVGI-----------GPFG----QGEKGEKGSLGLP---GPPGRDGSKGMRGE 552
            G KG+KG+ G+           GP G    QG +GE+G  G P   GP G DG  G+ G+
Sbjct: 110  GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ 169

Query: 553  PGELGEPG---------------------------------LPGEVGMRGPQGPPGLPGP 579
            PG  G PG                                 +PG VG  GP+GP GL G 
Sbjct: 170  PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQ 229

Query: 580  PGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGR---PGPSGVAGPQGEKGD 636
             G  G  G  GE G+ G  G  G RG +G PGKPG+ G+ GR   PG  G AG  G +G 
Sbjct: 230  QGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGF 289

Query: 637  VGPAGPPGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPGP------------PGARGPIGP 682
             G  G PG+ G    +  EG KGE GAPG +G  G  GP            PG RG +GP
Sbjct: 290  PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGP 349

Query: 683  EGRDGPPGLQGLRGKKGDMGPPGIPGLLGL------------------QGPPGPPGVPGP 724
            +G  G  G  G+ GK G MGP GIPG  G                   +GP G  G  GP
Sbjct: 350  QGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGP 409

Query: 725  PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGL 784
            PGP GSPGLPG IG  G PG  GPTG PG  GP G  GPPG+ G  G  G  G+ G+PG 
Sbjct: 410  PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGD 469

Query: 785  RGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGP 844
             G  G +G AG  GE G  G+ G  G PG  G++G +G+ G +G PG  G+RG  G  G 
Sbjct: 470  PGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGF 529

Query: 845  AGPPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGLPGEP------GLQGRPGELGPQGPT 897
             G  GLPG         R P G  GPKG +GDPG PGEP      GL G PG  GP+G  
Sbjct: 530  PGSDGLPGPKG--AQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKL 587

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP---SGPP------GSVGAPGLRGTPGKD 948
            GP GA G++G  G PG+ G  G PG +G PGP   SG P      G+ G PG RG PGKD
Sbjct: 588  GPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKD 647

Query: 949  GERGEK------GAAGEEGSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPL 1001
            GE G        G AGE G  GP GP G  G PG PGPPG+ GK G+ G+ G PG  GPL
Sbjct: 648  GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL 707

Query: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG----IGVAGPPGPSGPPG 1057
            G +   G                G+RG PGI G PG +G  G     G  G PGPSG PG
Sbjct: 708  GPRGERGN--------------PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPG 753

Query: 1058 DKGSPGSRGLP---GFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
            D G PG +G+P   G  G  GP G  G  G  G  G  G  G   L  PG +        
Sbjct: 754  DTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL--PGPLG------- 804

Query: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
               PPGP G  G  G  G +G+ G PG  G  G +GE GP G  G  G  GP G  G +G
Sbjct: 805  ---PPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861

Query: 1175 ADGEVGQKGDQGHP---------------GVPGFMGPPGNPGPPGADGIAGAA---GPPG 1216
              GE GQKGD G P               GVPG  G  G  GPPGA G  G+A   GPPG
Sbjct: 862  EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921

Query: 1217 IQGSPGKEGP---PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP---GLPGPEG 1270
              G+PG  GP   PG +GP GL G PG  G+ G  G  GPPG PG  G+P   G PGP+G
Sbjct: 922  PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981

Query: 1271 ARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNG 1330
              GP G  G  G  G PG RGE G  GLPG  G PGK G TG TG +GP GP GPPG NG
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041

Query: 1331 SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP---G 1387
              G PG  GP+         G +G+PG  G +G RG  G+PG  G+PG +G PG P   G
Sbjct: 1042 PVGEPGPEGPA---------GNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVG 1092

Query: 1388 EPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447
             PG  G+RGDPG +G  GPPG  G+ G PG  G +G  G  G +G  G+ G  G  G  G
Sbjct: 1093 APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG 1152

Query: 1448 QPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK 1507
             PG PG  GE                                   + S G PGP GP G 
Sbjct: 1153 LPGPPGPNGE-----------------------------------QGSAGIPGPFGPRGP 1177

Query: 1508 DGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQP 1567
               PG  GP G+ G PG      P GPIGP G RG+ G+ G       G  G PG PG P
Sbjct: 1178 ---PGPVGPSGKEGNPG------PLGPIGPPGVRGSVGEAGP-----EGPPGEPGPPGPP 1223

Query: 1568 GEPGYAKDGLPGIPGPQGETGPAGHPGL---PGPPGPPGQCDPSQCAYFASLAARPGNVK 1624
            G PG+    L  I G   E+ P   P        P    + DP   A   SL+++   ++
Sbjct: 1224 GPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKTDPGVHATLKSLSSQIETMR 1283

Query: 1625 GP 1626
             P
Sbjct: 1284 SP 1285



 Score =  833 bits (2151), Expect = 0.0
 Identities = 510/1157 (44%), Positives = 577/1157 (49%), Gaps = 112/1157 (9%)

Query: 502  GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL 561
            G   PV +  P G     G   FG+G KG+KG  GL          G+RG PG  G PG 
Sbjct: 90   GECCPVCSQTPGG-----GNTNFGRGRKGQKGEPGLVPVV-----TGIRGRPGPAGPPGS 139

Query: 562  PGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGR 621
             G  G RGP+G PG  GP G  G PG+ G+ G  G  G     G DG   +P      G 
Sbjct: 140  QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGL-SRPFSAQMAGL 198

Query: 622  PGPSGVAGPQG-EKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680
               SG+    G   G VGP GP G        +GL+G+QG  GP G  G PG PG  GPI
Sbjct: 199  DEKSGLGSQVGLMPGSVGPVGPRG-------PQGLQGQQGGAGPTGPPGEPGDPGPMGPI 251

Query: 681  GPEGRDGPPGLQGLRGKKGDMGPPG------IPGLLGLQGPPGPPGVPGPPGPGGSPGLP 734
            G  G +GPPG  G  G+ G  G PG       PG  G  G PG PG+ G  G  G  G  
Sbjct: 252  GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 735  GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE------PGERGEDGLPGKPGLRGEI 788
            GE+G PG  G  GPTGP G  GP GP G PG +G       PG+RG  G+PGKPG  G +
Sbjct: 312  GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 789  G---EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845
            G     G  G PG KGEAG  GA G  G +G++G+ G  G +G PGL G  G  G  G  
Sbjct: 372  GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431

Query: 846  GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 905
            GP G PGT+         PG  GP+G  G  G+ G+PG  G PG  G  GP G PG  G 
Sbjct: 432  GPTGSPGTSGP-PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI 490

Query: 906  EGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG---S 962
            +G  G PG  G  G  G  G  GP GP G  GAPG RG PG DG  G KGA GE G   S
Sbjct: 491  QGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGS 550

Query: 963  PGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021
             GP G +GDPG PG PG PG +G  G PG++G  G  GPLG                   
Sbjct: 551  SGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAP----------------- 593

Query: 1022 CVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGS------PGSRGLPGFPG-- 1072
               G+ G PG PGS G RG PG +G+ GP G SG PG  G       PG RG PG  G  
Sbjct: 594  ---GEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEV 650

Query: 1073 -PQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFK 1131
             P GP G  G  G  GE+GPPG  G   L                  PGPPG PG  G  
Sbjct: 651  GPSGPVGPPGLAGERGEQGPPGPTGFQGL------------------PGPPGPPGEGGKP 692

Query: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191
            GD+GVPG PG  G  G +GE G PG  G PGI G  G +G  G  G  G KG  G  G P
Sbjct: 693  GDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTP 752

Query: 1192 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251
            G  GPPG  G PG  GIAG  GP G +G  G++G  G  G  G  G+PG  G  G     
Sbjct: 753  GDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPG---PA 809

Query: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA---PGPRGESGAMGLPGQEGLPGKD 1308
            GP GE G+ G  GL GP G+RG PG +G  G +GA    GP+G  G  G+ G+ G PG+ 
Sbjct: 810  GPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQK 869

Query: 1309 GDTGPTGPQGPQGPRGPPGKNGSPG---SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 1365
            GD G  GPQG  G  GP G NG PG     G  GP G  G  GS G  G PG  G  GP 
Sbjct: 870  GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA 929

Query: 1366 GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHT 1425
            GP GEPG++G PG  G PG  G  G +G  G PG  GDKG PG  GQPG  G PG  G T
Sbjct: 930  GPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTT 989

Query: 1426 GLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA 1485
            G  G  G+PG+ G  G PG PG  G PG  G  P+  T  +     +G            
Sbjct: 990  GQRGIVGMPGQRGERGMPGLPGPAGTPGKVG--PTGATGDKGPPGPVGPPGSNGPVGEPG 1047

Query: 1486 QMPPAYMKSSQGR------------PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG 1533
               PA    + GR            PGP G PG  G PG  GP+G PG  GQ G  G  G
Sbjct: 1048 PEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG 1107

Query: 1534 PIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAK-DGLPGIPGPQGETGPAG 1591
            PIGP G  G +G PG  G  G +G+ G  G  GQ G  G+    GLPG PGP GE G AG
Sbjct: 1108 PIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAG 1167

Query: 1592 HPGLPGPPGPPGQCDPS 1608
             PG  GP GPPG   PS
Sbjct: 1168 IPGPFGPRGPPGPVGPS 1184



 Score =  814 bits (2102), Expect = 0.0
 Identities = 506/1161 (43%), Positives = 572/1161 (49%), Gaps = 197/1161 (16%)

Query: 442  PCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDI 501
            P  V VVT     P P  PP  GS+            P GE+G  G  GP G  G  G+ 
Sbjct: 118  PGLVPVVTGIRGRPGPAGPP--GSQG-----------PRGERGPKGRPGPRGPQGIDGEP 164

Query: 502  GAIGPVGAPGPKGEKGDVGIG----PF-----GQGEK-----------GEKGSLGLPGPP 541
            G  G  GAPGP G     G      PF     G  EK           G  G +G  GP 
Sbjct: 165  GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224

Query: 542  GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEK 601
            G  G +G  G  G  GEPG PG +G  G +GP G PG PG  G PG  G  GE G  G  
Sbjct: 225  GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSP 284

Query: 602  GERGLDGFPGKPG------------DTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV 649
            G RG  G PG PG              G+ G PG  G AGP G  G +GP GP G+PG  
Sbjct: 285  GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPG-- 342

Query: 650  VQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGL 709
              + G  G QGAPG RG  G PG PG  GP+G  G  G PG  G+   KG+ GP G  G 
Sbjct: 343  --ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGM---KGEAGPTGARGP 397

Query: 710  LGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGE 769
               +GP G  G  GPPGP GSPGLPG IG  G PG  GPTG PG  GP G  GPPG+ G 
Sbjct: 398  ---EGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454

Query: 770  PGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGL 829
             G  G  G+ G+PG  G  G +G AG  GE G  G+ G  G PG  G++G +G+ G +G 
Sbjct: 455  QGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGP 514

Query: 830  PGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGLPGEPGLQG-- 886
            PG  G+RG  G  G  G  GLPG         R P G  GPKG +GDPG PGEPGL G  
Sbjct: 515  PGPVGERGAPGNRGFPGSDGLPGPKG--AQGERGPVGSSGPKGSQGDPGRPGEPGLPGAR 572

Query: 887  ----RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP---SGPPG----- 934
                 PG  GP+G  GP GA G++G  G PG+ G  G PG +G PGP   SG PG     
Sbjct: 573  GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEA 632

Query: 935  -SVGAPGLRGTPGKDGERGEKGA------AGEEGSPGPVGPRGDPGAPGLPGPPGKG-KD 986
             + G PG RG PGKDGE G  G       AGE G  GP GP G  G PG PGPPG+G K 
Sbjct: 633  GNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP 692

Query: 987  GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG--- 1043
            G+ G+ G PG  GPLG +   G                G+RG PGI G PG +G  G   
Sbjct: 693  GDQGVPGDPGAVGPLGPRGERGN--------------PGERGEPGITGLPGEKGMAGGHG 738

Query: 1044 -IGVAGPPGPSGPPGDKGSPGSRGLPG---FPGPQGPAGRDGAPGNPGERGPPGKPGLSS 1099
              G  G PGPSG PGD G PG +G+PG     G  GP G  G  G  G  G  G  G   
Sbjct: 739  PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG 798

Query: 1100 LLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPG 1159
            L  PG +           PPGP G  G  G  G +G+ G PG  G  G +GE GP G  G
Sbjct: 799  L--PGPLG----------PPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVG 846

Query: 1160 PPGIAGPQGSQGERGADGEVGQKGDQGHPG---------------VPGFMGPPGNPGPPG 1204
              G  GP G  G +G  GE GQKGD G PG               VPG  G  G  GPPG
Sbjct: 847  FAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPG 906

Query: 1205 ADGIAGAAG---PPGIQGSPGKEGP---PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG 1258
            A G  G+AG   PPG  G+PG  GP   PG +GP GL G PG  G+ G  G  GPPG PG
Sbjct: 907  ATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPG 966

Query: 1259 KAGEPG---LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 1315
              G+PG    PGP+G  GP G  G  G  G PG RGE G  GLPG  G PGK G TG TG
Sbjct: 967  DKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATG 1026

Query: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSG---TPGQKGSKGENG------------SPGLPG 1360
             +GP GP GPPG NG  G PG  GP+G   TPG+ G+ GE G            S G PG
Sbjct: 1027 DKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPG 1086

Query: 1361 FLGPRGPPGEPGEKGVPG------------KEGVPGKPGEPGFKGERGDPGIKGDKG--- 1405
              GP G PG+ G++G PG            K G+PG  G  G KG+ GD G +G KG   
Sbjct: 1087 TPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRG 1146

Query: 1406 ---------PPGGKGQPGDPGIPG---------------HKGHTGLMGPQGLPG------ 1435
                     PPG  G+ G  GIPG                +G+ G +GP G PG      
Sbjct: 1147 FTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVG 1206

Query: 1436 ENGPVGPPGPPGQPGFPGLRG 1456
            E GP GPPG PG PG PG  G
Sbjct: 1207 EAGPEGPPGEPGPPGPPGPPG 1227



 Score =  790 bits (2039), Expect = 0.0
 Identities = 480/1159 (41%), Positives = 573/1159 (49%), Gaps = 161/1159 (13%)

Query: 439  PSGPCQVT----VVTEPPPPPPPQRPPTPGSE---------------------QIGFLK- 472
            P GP  +     V  +P  P PP  P  PG +                     Q+G +  
Sbjct: 154  PRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPG 213

Query: 473  ---TINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG--------- 520
                +    P G +G+ G AGP G PG  GD G +GP+G+ GP+G  G  G         
Sbjct: 214  SVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNG 273

Query: 521  ----IGPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQG--- 572
                +G  G  G +G  G+ GLPG  G  G KG+ G  GE+G PG  GE G  GP G   
Sbjct: 274  NPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMG 333

Query: 573  ---PPGLPGPPGRVGAPGLQGERGEKGTRGEKGERG------LDGFPGKPGDTGQQGRPG 623
               P G+PG  GR+G  G  G+RG  G  G+ G  G        GFPG PG  G+ G  G
Sbjct: 334  PLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTG 393

Query: 624  PSGVAGPQGEKGDVGPAGP---PGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPGPPGARG 678
              G  GPQG++G+ GP GP   PG+PG++      G KG  G+PG  G  G+ GPPG+ G
Sbjct: 394  ARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPG 453

Query: 679  P---IGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG------------VPG 723
            P    GP+G  G PG  G+ G KG+ GP G PG  G+QGP GPPG              G
Sbjct: 454  PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG 513

Query: 724  PPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG 783
            PPGP G  G PG  GFPG  G PGP G  G+ GP G  GP G++G+PG  GE   PG PG
Sbjct: 514  PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE---PGLPG 570

Query: 784  LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 843
             RG  G  G+ G  G+ G  G PG  G PG  G  G +G+ G +GLPG KG  G+ G+ G
Sbjct: 571  ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPG 630

Query: 844  PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903
             AG  G+PG        P   GE GP G  G PGL GE G QG PG  G QG  GPPG  
Sbjct: 631  EAGNAGVPGQRGA----PGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPP 686

Query: 904  GQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSP 963
            G+ G  G  G  G+PGA G +G  G  G PG  G PG+ G PG+ G  G  G  G +GSP
Sbjct: 687  GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP 746

Query: 964  GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCAL--GGQ 1021
            GP G  GD G PGL G PG+        RG  G PGP G +   G+ +G+E  A   G +
Sbjct: 747  GPSGTPGDTGPPGLQGMPGE--------RGIAGTPGPKGDRGGIGE-KGAEGTAGNDGAR 797

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080
             + G  G PG  G  G +G+PG  G+ GPPG  G PG +G  G  G  GF GPQGP G+ 
Sbjct: 798  GLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQP 857

Query: 1081 GA---PGNPGERGPPGKPGLSSLL-SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 1136
            G    PG PG++G  G PG   L  SPG             P GP G+PGL G +G +G 
Sbjct: 858  GVKGEPGEPGQKGDAGSPGPQGLAGSPG-------------PHGPNGVPGLKGGRGTQGP 904

Query: 1137 PGKPGREGTEGKKGEAGPPGLPGP------PGIAGPQGSQGERGADGEVGQKGDQGHPGV 1190
            PG  G  G+ G+ G  GP G PGP      PG  GP G +G+ G+ G VG +G  G PG 
Sbjct: 905  PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG 964

Query: 1191 PGFMGPPGN---PGPPGADGIAGAAGPPGIQGSPGKEGP---PGPQGPSGLPGIPGEEGK 1244
            PG  G PG    PGP G  G AG  G  GI G PG+ G    PG  GP+G PG  G  G 
Sbjct: 965  PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024

Query: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 1304
             G  G PGP G PG  G  G PGPEG  G  G  G  G  G  G RG+ G  GLPG +G 
Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084

Query: 1305 PGKDG------DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358
            PG  G      D G  G  G +GP GPPG+ G  G PG  GP G  G  G +G+ G  G 
Sbjct: 1085 PGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGH 1144

Query: 1359 PGFLGPRGPPGEPGEKGVPGKEGVPG---------------KPGEPGFKGERGDPGIKGD 1403
             GF G +G PG PG  G  G  G+PG               K G PG  G  G PG++G 
Sbjct: 1145 RGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGS 1204

Query: 1404 ------KGPPGGKGQPGDPGIPGH--------KGHTGLMGPQGLPGENGPVGPPGPPGQ- 1448
                  +GPPG  G PG PG PGH         GH     P  LP        P    + 
Sbjct: 1205 VGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPEFTEDQAAPDDKNKT 1264

Query: 1449 -PGFPG-LRGESPSMETLR 1465
             PG    L+  S  +ET+R
Sbjct: 1265 DPGVHATLKSLSSQIETMR 1283



 Score =  375 bits (964), Expect = e-103
 Identities = 245/599 (40%), Positives = 283/599 (47%), Gaps = 69/599 (11%)

Query: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPG----ERGPPGKPGLSSLLSPGDIN 1107
            P  PPG+   P     PG        GR G  G PG      G  G+PG           
Sbjct: 85   PVTPPGEC-CPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPG----------- 132

Query: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIA--- 1164
                      P GPPG  G  G +G KG PG  G +G +G+ G  G PG PGPPG     
Sbjct: 133  ----------PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHP 182

Query: 1165 GPQG-----SQGERGADGEVGQKGDQG-HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 1218
            GP G     S    G D + G     G  PG  G +GP G  G  G  G AG  GPPG  
Sbjct: 183  GPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEP 242

Query: 1219 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 1278
            G PG  GP G +GP G PG PGE+G+ GR+G PG   E G AG PG  G  GA G PG K
Sbjct: 243  GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPG---EVGFAGSPGARGFPGAPGLPGLK 299

Query: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG------PRGPPGKNGSP 1332
            GH G  G  GP+GE GA G  G+ G  G  G  GP GP+G  G      P+G PG+ G+ 
Sbjct: 300  GHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAH 359

Query: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGP---RGPPGEPGEKGVPGKEGVPGKPGEP 1389
            G PG+PGP G  G  GS G  G+PG+ G  GP   RGP G  G++G  G  G  G PG P
Sbjct: 360  GMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLP 419

Query: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 1449
            G  G  G PG KG  G PG  G PG  G PG  G  G  GPQG+ G+         PG P
Sbjct: 420  GAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ---------PGDP 470

Query: 1450 GFPGLRGES-PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKD 1508
            G PG +GE+ P  E     IQ  +G   E        +  P   +   G  GPPGP G+ 
Sbjct: 471  GVPGFKGEAGPKGEPGPHGIQGPIGPPGEE------GKRGP---RGDPGTVGPPGPVGER 521

Query: 1509 GLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQP 1567
            G PG  G  G  G PG  G +G  GP+G  G +G++GDPG PG  GL G  G  G PG  
Sbjct: 522  GAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQ 581

Query: 1568 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            G  G  K G  G PG  G  GP G  G+ G PG  G   P   +         GN   P
Sbjct: 582  GPEG--KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP 638


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  855 bits (2210), Expect = 0.0
 Identities = 515/1204 (42%), Positives = 591/1204 (49%), Gaps = 163/1204 (13%)

Query: 480  AGEKGEMG----------VAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEK 529
            AGEKG  G            GP G PGP+G    +GP G PGP G  GD           
Sbjct: 372  AGEKGAKGEPAVIEKGQQFEGPPGAPGPQG---VVGPSGPPGPPGFPGD----------P 418

Query: 530  GEKGSLGLPGPPGRDGSKGMRGE----PGELGEPGLPG-----------------EVGMR 568
            G  G  GLPG PG DG +G  G     P +       G                 ++ M+
Sbjct: 419  GPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMK 478

Query: 569  GPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA 628
            GP GP GL G PG VG PG  G +GE+G  G +G RGL G  G PG  G+ GRPG  G  
Sbjct: 479  GPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGAR 538

Query: 629  GPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP 688
            G  G+ G  G  G  G+PG       L GE+G  G  GH G PGPPG  G  G EG  GP
Sbjct: 539  GLPGDTGPKGDRGFDGLPG-------LPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP 591

Query: 689  PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGP 748
             G           G PG  GLLG +G PGP G PG  G  G+PG  G +G PG+PGPPG 
Sbjct: 592  TG---------QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQ 642

Query: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808
             G  G  G  GP G  GT GE G  G  G+PG PG  G +G  G  G  GEKG  G PG+
Sbjct: 643  QGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGS 702

Query: 809  ---PGFPGVRGEKG---------DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856
               PG+PG RG KG         ++GEKGE G PG KGD G KG+ G  G PG  G    
Sbjct: 703  AGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762

Query: 857  FTPHPRM--------PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGA 908
              P  +         PG  G KG+ G PGLPG PG  G  G +G  GP GP G KG+ G 
Sbjct: 763  EGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGK 822

Query: 909  HGAPGAAGN---PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965
             G PG  G    PG+ G  G PG +G PG  G  G  G PG  GE+G  G  G  G PGP
Sbjct: 823  TGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGP 882

Query: 966  VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025
             GP G  G  G PG PG+   GE G +G  G PGP G     GK         G     G
Sbjct: 883  KGPPGHQGKDGRPGHPGQR--GELGFQGQTGPPGPAGVLGPQGKT--------GEVGPLG 932

Query: 1026 DRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG 1084
            +RG PG PG PG +G PG+ G  G  G  GPPG  G  G  GL GFPGP+G  G  G  G
Sbjct: 933  ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG 992

Query: 1085 NPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCP-----PGPPGLPGLPGFKGDKGVPGK 1139
              G++GPPG  G +   SPG+   L        P      GP G  G  G +G++G PG 
Sbjct: 993  LKGDKGPPGPVGANG--SPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 1140 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 1199
             G++G  G  G  GPPG  GP G  G +G  G  G  G  G KGD G PG PG  GP G+
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 1200 PGPPGADGIAGAAGPPGIQGSPGKEGPPG------PQGPSGLPGIPGEEGKEGRDGKPGP 1253
            PGPPGADG  G  GPPG+ G  G +G  G      P G  GLPG PGE+G+ G  G  GP
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 1313
             G PG  G  G  G EG  G PG  G  G  G  G RG++G  G PG  G+PG  GD G 
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230

Query: 1314 TGPQGPQGPRGPPGKNGSP---GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE 1370
             G  GP G  GPPGK G P   G+ G  GP+G PG  G  G+ G  G+ G  G +G PG+
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290

Query: 1371 PGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP 1430
             G  G PG  G PG PG PG +G  G  G +G +G  G KG+PG  G PG  G  G  GP
Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGP 1350

Query: 1431 QGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490
             G  G  G  G PGP G+PG  G  G+                                 
Sbjct: 1351 PGRVGPEGLRGIPGPVGEPGLLGAPGQ--------------------------------- 1377

Query: 1491 YMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA------- 1543
                  G PGP GP G  GL G  GP GE G  G  GL GP G  G KG++G        
Sbjct: 1378 -----MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPP 1432

Query: 1544 --KGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1600
              KGDPG PG +G  G  GPPG+ G  G+ G    G PG  GP+G+TGPAG PG   PPG
Sbjct: 1433 GPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG--SKGSPGSMGPRGDTGPAGPPG---PPG 1487

Query: 1601 PPGQ 1604
             P +
Sbjct: 1488 APAE 1491



 Score =  837 bits (2162), Expect = 0.0
 Identities = 509/1159 (43%), Positives = 588/1159 (50%), Gaps = 151/1159 (13%)

Query: 479  PAGEKGEMGVAGPMGLPGPKG---DIGAIGPVGAPGP------KGEKGDVGIGPF---GQ 526
            P G  G  GV GP G PGP G   D G  GP G PG       +G  G V + PF   G 
Sbjct: 393  PPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGG 452

Query: 527  GEKG--------------EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQG 572
              KG              ++  L + GPPG  G  G  G  G  G PGL GE G  GPQG
Sbjct: 453  SFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQG 512

Query: 573  PPGLPGP---PGRVGA---PGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSG 626
            P GL GP   PGRVG    PG  G RG  G  G KG+RG DG PG PG+ GQ+G  G  G
Sbjct: 513  PRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVG 572

Query: 627  VAGPQGEKGDVGPAGPPGVPGSVVQQ--EGLKGEQGAPGPRGHQGAPG---PPGARGPIG 681
              GP GE G+ G  GPPG  G   +    GL G +G+PGP G  G  G    PGA+G +G
Sbjct: 573  QPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVG 632

Query: 682  PEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPP---GPGGSPGLPGEIG 738
            P G  GPPG QG  G +G  GP G+ G  G +GPPG PG+PG P   GP G PG  G  G
Sbjct: 633  PPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTG 692

Query: 739  FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG 798
              G  GPPG  GPPG  GP G  G  G +G  GE+GE G  G PG +G++G +G  G+PG
Sbjct: 693  EKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPG 752

Query: 799  EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT-SLF 857
                   PG  G  G  G KG  G+ GE G PG  G++G+ G  G  G PG PG   S+ 
Sbjct: 753  A------PGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIG 806

Query: 858  TPHPRMP-GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 916
             P P  P GE+G  G+ G PGL GE G  G  GE G  G TG PG KG  G  GAPG  G
Sbjct: 807  FPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPG 866

Query: 917  NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGP----------- 965
              G PG  G PG  GP G  G  G  G PG  G+RGE G  G+ G PGP           
Sbjct: 867  EKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTG 926

Query: 966  -VGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVK 1024
             VGP G+ G PG PGPPG+   G PGL G  G  G LG     GK              +
Sbjct: 927  EVGPLGERGPPGPPGPPGE--QGLPGLEGREGAKGELGPPGPLGK--------------E 970

Query: 1025 GDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRG---------LPGFPGPQ 1074
            G  G  G PG  G  GDPG  G+ G  GP GP G  GSPG RG         LPG  G +
Sbjct: 971  GPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSE 1030

Query: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134
            GP G  G  G+ GERGPPG  G   +  PG +           P GPPG  G  G +GDK
Sbjct: 1031 GPVGPAGKKGSRGERGPPGPTGKDGI--PGPLG----------PLGPPGAAGPSGEEGDK 1078

Query: 1135 GVPGKPGREGTEGKKGEAGP---PGLPGPPGIAGP---QGSQGERGADGEVGQKGDQGHP 1188
            G  G PG +G++G KG+AGP   PG+ GP G  GP    G+QG RG  G  GQKGD G  
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 1189 GVPGFMGPPGN---PGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKE 1245
            G  G +GPPG    PGPPG  G  G  G  G  G+PG  GP GP G  G PG+PG  G+ 
Sbjct: 1139 GFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQ- 1197

Query: 1246 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP 1305
                 PG  GE G+ G+ G PGP GA G PG KG  G+ G  GP   SGA G PG++G P
Sbjct: 1198 -----PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGP---SGAAGPPGKKGPP 1249

Query: 1306 GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 1365
            G+DG  G  GP G  G  GPPG       PG  G  G+PG+KG  G+ G PG PG  G  
Sbjct: 1250 GEDGAKGSVGPTGLPGDLGPPG------DPGVSGIDGSPGEKGDPGDVGGPGPPGASGEP 1303

Query: 1366 GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHT 1425
            G PG PG++G  G  G  G+ GE G KGE G  G  G  GP G +G PG  G  G +G  
Sbjct: 1304 GAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIP 1363

Query: 1426 GLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLA 1485
            G +G  GL G  G +GPPGP G  G PGL+G++              G++    L  L+ 
Sbjct: 1364 GPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPK-----------GEKGHIGLIGLIG 1412

Query: 1486 QMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP-------------- 1531
                A  K  QG PG  GPPG  G PG  GP+G  G PG  G+ GP              
Sbjct: 1413 PPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMG 1472

Query: 1532 ----SGPIGPKGERGAKGD 1546
                +GP GP G  GA  +
Sbjct: 1473 PRGDTGPAGPPGPPGAPAE 1491



 Score =  813 bits (2099), Expect = 0.0
 Identities = 562/1463 (38%), Positives = 679/1463 (46%), Gaps = 217/1463 (14%)

Query: 281  TEDVFPQG-LPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNA 339
            T ++FP+G  P+ ++ + T R +  ++     +  + D+    Q+ + L          A
Sbjct: 77   TWELFPEGHFPENFSLLITLRGQPANQS---VLLSIYDERGARQLGLALGP--------A 125

Query: 340  VGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQ 399
            +G + D  R +    +VN L D  WH++A+SI  + V+L  DC     +       I I 
Sbjct: 126  LGLLGDPFRPL--PQQVN-LTDGRWHRVAVSIDGEMVTLVADCEAQPPVLGHGPRFISIA 182

Query: 400  GKTVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETC------CDIPSGPCQVTVVTEPPP 453
            G TV+G +       + D+Q ++I  D + A  + C      CD  +    V    EP  
Sbjct: 183  GLTVLGTQDLGEKTFEGDIQELLISPDPQ-AAFQACERYLPDCDNLAPAATVAPQGEPET 241

Query: 454  PPPPQRPPTPGSEQIGFLK--------TINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIG 505
            P P ++    G ++    K         I  S P  +  E   +  +    PK +  A  
Sbjct: 242  PRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDI----PKTETPAPN 297

Query: 506  PVGAPGPKGEKGDVGIG-----------PFGQGEKG----------EKGSLGLPGPPGRD 544
                P P      V  G           P    E G          E+G     GP  R 
Sbjct: 298  LPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFRA 357

Query: 545  GSKGMRGE----PGELGEPGLPGEVGM--RGPQ--GPPGLPGPPGRVGAPGLQGERGEKG 596
                 R +    PG  GE G  GE  +  +G Q  GPPG PGP G VG            
Sbjct: 358  AEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPS---------- 406

Query: 597  TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQG-------EKGDVGPAGPP----GV 645
              G  G  G  G PG PG  G  G PG  G+ GP G       +       GPP      
Sbjct: 407  --GPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464

Query: 646  PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705
                V Q+     +G PGP G  G PGP G  G  G +G +G  G QG RG +G  GPPG
Sbjct: 465  QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524

Query: 706  IPGLLGLQGPPGPPGVPGPPGPGGS------PGLPGEIGFPGKPGPPGPTGPPGKDGPNG 759
              G +G  G  G  G+PG  GP G       PGLPGE G  G  G  G  GPPG+DG  G
Sbjct: 525  RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584

Query: 760  ---PPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRG 816
               PPGP G  GEPG RG  G  G PG  G  G  G+ G PG KG  G PG PG PG +G
Sbjct: 585  AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644

Query: 817  EKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDP 876
              G QG      LPG +G  G  GE GP G PG+PG          +PG  GP G  G  
Sbjct: 645  NHGSQG------LPGPQGLIGTPGEKGPPGNPGIPG----------LPGSDGPLGHPGHE 688

Query: 877  GLPGEPGLQGRPGELGPQGPTGPPGAKG---QEGAHGAPGAAGNPGAPGHVGAPGPSGPP 933
            G  GE G QG PG  GP G  GP G KG     G  G  G  G  G PG  G  G  G  
Sbjct: 689  GPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQ 748

Query: 934  GSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRG 993
            G  GAPG RG  G +G +G+ G AGEEG PG  G +G  G PGLPG PG+     PG +G
Sbjct: 749  GKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGR-----PGPKG 803

Query: 994  SPGLPGPLGTKAACGKVRGSENCALGGQC----VKGDRGAPGIPGSPGSRGDPGIGVAGP 1049
            S G PGPLG     GK   +    L G+      +G+RG PG  G PG +GD      G 
Sbjct: 804  SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGD-----VGQ 858

Query: 1050 PGPSGPPGDKGSPGSRGLPGFPGPQGPAG---RDGAPGNPGERGP------PGKPGLSSL 1100
             G  G PG+KG PG +G PGFPGP+GP G   +DG PG+PG+RG        G PG + +
Sbjct: 859  DGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGV 918

Query: 1101 LSP----GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 1156
            L P    G++  L +      PPGPPG  GLPG +G +G  G+ G  G  GK+G AG  G
Sbjct: 919  LGPQGKTGEVGPLGERGPPG-PPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRG 977

Query: 1157 LPGP---PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAG 1213
             PGP   PG  GP G +G++G  G VG  G    PG  G +GP G  G PG  G  G  G
Sbjct: 978  FPGPKGGPGDPGPTGLKGDKGPPGPVGANGS---PGERGPLGPAGGIGLPGQSGSEGPVG 1034

Query: 1214 PPGIQGSPGKEGPPGPQGPSGLPG------------------------IPGEEGKEGRDG 1249
            P G +GS G+ GPPGP G  G+PG                         PG +G +G  G
Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG 1094

Query: 1250 KPGPPGEPGKAGEPGLPGPEGA------RGPPGFKGHTGDSGAPG---PRGESGAMGLPG 1300
              GPPG+PG  G  G PGP GA      RGPPG  G  GD G  G     G  G  GLPG
Sbjct: 1095 DAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG 1154

Query: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS----- 1355
              G  G+ GD G  GP G  GPRGP G  GS G+PG PG  G PG  G KGE G      
Sbjct: 1155 PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPG 1214

Query: 1356 -PGLPGFLGPRGPPGEPGEKGVPGKEGVPGK---PGEPGFKGERGDPGIKGDKGPPGGKG 1411
             PG PG  GP+G  GE G+ G  G  G PGK   PGE G KG  G  G+ GD GPPG  G
Sbjct: 1215 PPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPG 1274

Query: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471
              G  G PG KG  G +G  G PG +G  G PGPPG+ G  G  G               
Sbjct: 1275 VSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGRE------------- 1321

Query: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGP 1531
             G++ E           P       G  GPPG  G +GL G  GP+GEPG  G  G  GP
Sbjct: 1322 -GREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGP 1380

Query: 1532 SGPIGPKGERGAKGDPGAPG----VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET 1587
             GP+GP G  G KGD G  G    +GL G +GPPG  G+ G+ G    G+ G PGP+G+ 
Sbjct: 1381 PGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLP--GVQGPPGPKGDP 1438

Query: 1588 GPAG------HPGLPGPPGPPGQ 1604
            GP G      HPG PG  GP GQ
Sbjct: 1439 GPPGPIGSLGHPGPPGVAGPLGQ 1461



 Score =  714 bits (1842), Expect = 0.0
 Identities = 438/1045 (41%), Positives = 507/1045 (48%), Gaps = 132/1045 (12%)

Query: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGR-- 685
            A  + E+GD    GP         +   +   GA    G +GA G P     +  +G+  
Sbjct: 339  AAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGA----GEKGAKGEPA----VIEKGQQF 390

Query: 686  DGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI-----GFP 740
            +GPPG  G +G  G  GPPG PG  G  GPPGP G+PG PG  G  G PG +      F 
Sbjct: 391  EGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFA 450

Query: 741  GKP--GPP-----------------GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781
            G    GPP                    GPPG  G  G PGP G  G PG +GE+G  G 
Sbjct: 451  GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGP 510

Query: 782  PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841
             G RG  G  G  GR G+ G  G  GA G PG  G KGD+G  G  GLPG KG RG+ G 
Sbjct: 511  QGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGH 570

Query: 842  AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901
             G  GPPG                E G +G +G PG  G+ G  G  G LGP+G  GP G
Sbjct: 571  VGQPGPPG----------------EDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTG 614

Query: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961
              G  G  GAPGA GN G PG  G PG  G  GS G PG +G  G  GE+G  G  G  G
Sbjct: 615  RPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPG 674

Query: 962  SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021
             PG  GP G PG  G  G   KG  G PG  G PG PGP G K   G  RG +    G +
Sbjct: 675  LPGSDGPLGHPGHEGPTGE--KGAQGPPGSAGPPGYPGPRGVKGTSGN-RGLQ----GEK 727

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077
              KG+ G PG  G  G +GD G     G  G  GP GP G  G  G  G PG  G +G  
Sbjct: 728  GEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKL 787

Query: 1078 GRDGAPGNPGERGPPGKPGLSSLLSP-GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 1136
            G  G PG PG  GP G  G    L P G+     K       PG  G  G PG +G++G 
Sbjct: 788  GVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTG----QPGLEGERGPPGSRGERGQ 843

Query: 1137 PGKPGREGTEGKKGEAGPPGLPGP---PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 1193
            PG  G+ G +G  G+ G PG+PG    PG+ GP G  G +G  G  G+ G  GHPG  G 
Sbjct: 844  PGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903

Query: 1194 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 1253
            +G  G  GPPG  G+ G  G  G  G  G+ GPPGP GP G  G+PG EG+EG  G+ GP
Sbjct: 904  LGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGP 963

Query: 1254 PGEPGKAGEPGL---PGPEGARGPPGFKGHTGDSGAPGP------RGESGAMGLPGQEGL 1304
            PG  GK G  GL   PGP+G  G PG  G  GD G PGP       GE G +G  G  GL
Sbjct: 964  PGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023

Query: 1305 PGKDGDTGPTGP---QGPQGPRGPPGKNGSPGSPGEPGPSGTPG------QKGSKGENGS 1355
            PG+ G  GP GP   +G +G RGPPG  G  G PG  GP G PG      ++G KG+ G+
Sbjct: 1024 PGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGA 1083

Query: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKG---------- 1405
            PG  G  G +G  G PG+ G+ G  G PG PG  G +G RG PG+ G KG          
Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGV 1143

Query: 1406 --PPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMET 1463
              PPG +G PG PG  G  G  G MGP G PG  GP GP G  G PG PG  G+  ++  
Sbjct: 1144 IGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGE 1203

Query: 1464 LRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRP 1523
                                         K  +G  G PGPPG  G+PG  G +GE G  
Sbjct: 1204 -----------------------------KGERGDAGDPGPPGAPGIPGPKGDIGEKGDS 1234

Query: 1524 GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGP 1583
            G  G  GP G  GP GE GAKG  G    GL G++GPPG PG  G  G    G  G PG 
Sbjct: 1235 GPSGAAGPPGKKGPPGEDGAKGSVGP--TGLPGDLGPPGDPGVSGIDG--SPGEKGDPGD 1290

Query: 1584 QGETGPAGHPGLPGPPGPPGQCDPS 1608
             G  GP G  G PG PGPPG+  PS
Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPS 1315



 Score =  589 bits (1518), Expect = e-168
 Identities = 366/896 (40%), Positives = 428/896 (47%), Gaps = 146/896 (16%)

Query: 811  FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPK 870
            FPG  GEKG +GE   +       ++G++ E    GPPG PG   +  P        GP 
Sbjct: 369  FPGA-GEKGAKGEPAVI-------EKGQQFE----GPPGAPGPQGVVGP-------SGPP 409

Query: 871  GEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP------------ 918
            G  G PG PG PG  G PG  G  G  GPPG         A G+   P            
Sbjct: 410  GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469

Query: 919  ---------GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPR 969
                     G PG VG  G  GP G  G PGL+G  G +G +G +G  G  G PG VG  
Sbjct: 470  LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 970  GDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028
            G PGA G  G PG  G  G+ G  G PGLPG  G +   G V        G     G+RG
Sbjct: 530  GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQP-----GPPGEDGERG 584

Query: 1029 APGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPG 1087
            A G PG  G  G+PG  G+ GP G  GP G  G  G  G PG  G  GP G  G PG  G
Sbjct: 585  AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644

Query: 1088 ERGPPGKPGLSSLL-SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
              G  G PG   L+ +PG+              GPPG PG+PG  G  G  G PG EG  
Sbjct: 645  NHGSQGLPGPQGLIGTPGE-------------KGPPGNPGIPGLPGSDGPLGHPGHEGPT 691

Query: 1147 GKKGEAGPPGLPGPPGIAGPQG---SQGERGADGEVGQKGDQGHPGVPG---FMGPPGNP 1200
            G+KG  GPPG  GPPG  GP+G   + G RG  GE G+KG+ G PG  G     G  G P
Sbjct: 692  GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751

Query: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG------LPGIPGEEGKEGRDGKPGPP 1254
            G PG  G  G  GP G  G  G+EGPPG  G  G      LPG PG  G +G  G PGP 
Sbjct: 752  GAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL 811

Query: 1255 G---EPGKAGEPGLPGPEGARGPPGFKGHTGDSGA---PGPRGE---SGAMGLPGQEGLP 1305
            G   E GK+G+ G PG EG RGPPG +G  G  GA   PGP+G+    GA G+PG++GLP
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 1306 GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE---------PGPSGTPGQKGSKGENGSP 1356
            G  G  G  GP+GP G +G  G+ G PG  GE         PGP+G  G +G  GE G  
Sbjct: 872  GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 1357 GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 1416
            G  G  GP GPPGE G  G+ G+EG  G+ G PG  G+ G  G++G  GP GG G PG  
Sbjct: 932  GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991

Query: 1417 GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 1476
            G+ G KG  G +G  G PGE GP+GP G  G PG  G  G                    
Sbjct: 992  GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGP------------------- 1032

Query: 1477 ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 1536
                      + PA  K S+G  GPPGP GKDG+PG  GP+G PG  G  G EG  G +G
Sbjct: 1033 ----------VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082

Query: 1537 PKGERGAKGD------PGAPGV-------------GLRGEMGPPGIPGQPGEPGY----- 1572
              G +G+KGD      PG PG+             G +G  GPPG+ GQ G+ G      
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142

Query: 1573 --AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
                 GL G+PGP GE G  G  G  GP G PG   P            PG V  P
Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP 1198


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score =  828 bits (2138), Expect = 0.0
 Identities = 563/1415 (39%), Positives = 651/1415 (46%), Gaps = 324/1415 (22%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG-PFGQ------------- 526
            G KG+ G  G  G+ GPKGD+GA G  G PG  G  G  G G P G+             
Sbjct: 85   GRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDS 144

Query: 527  GEKGEKGSLGLPGPPGRDGSKGMRGEPGEL---------GEPGLPGEVGMRGPQGPPGLP 577
            G +G  GS G  GPPG  G KG +GEP  L         GEPG PG VG +GP G PG  
Sbjct: 145  GPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHV 204

Query: 578  GPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAG-------- 629
            G  G VGAPG  G  G  G +G++G RGL GF G  G+ G  G+PGP+G+          
Sbjct: 205  GQMGPVGAPGRPGPPGPPGPKGQQGNRGL-GFYGVKGEKGDVGQPGPNGIPSDTLHPIIA 263

Query: 630  -------PQGEKGDVGPAGPPGVPGSVVQQE-------------GLKGEQGAPGPRGHQG 669
                   P   KG+ G  G PG+ G  ++ E             GL GE+G+PG +G +G
Sbjct: 264  PTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRG 323

Query: 670  APGPPGARGPIGPEGRDGPPGLQGL----------RGKKGDMGPPGIPGLLGLQGPPGPP 719
              G  G  GP GP+G  G PG  GL          +G +GD G PG  G  G QG PG P
Sbjct: 324  LDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDP 383

Query: 720  GVPGPPGPG--------GSPGLPGEIGFPGKPGPPGPTG-PPGKDGPNGPPGPPGTKGEP 770
            G+PGPPG          G PG  G  GF G PG P   G PPG DG  GPPGPPG  G P
Sbjct: 384  GLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPP 443

Query: 771  GE----------RGEDGLPGKPGLRGEIGEQGLAGRPGE----------KGEAGLPGAPG 810
            G           +G  G PG PG  G  G +G  G  GE          KG  GLPG  G
Sbjct: 444  GPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKG 503

Query: 811  FPGVRGE---KGDQGEKGELGLPGLKGDRGEKGEAGPAGP------------------PG 849
            F G+ GE   KGD+G+ G+ GLPG  G +G  G  G  GP                  PG
Sbjct: 504  FAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPG 563

Query: 850  LPGTTSL--------------FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQG 895
            +PG   +              F   P  PG+ G KG  GDPG PG PG +G PGE+GP G
Sbjct: 564  VPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-GIKGPPGDPGYPGIPGTKGTPGEMGPPG 622

Query: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV------------------- 936
              G PG KGQ G    PG AG PG PG +G PGP+G PG +                   
Sbjct: 623  -LGLPGLKGQRGF---PGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQ 678

Query: 937  --------GAPGLRGTPGKDGERGEKGA---AGEEGSPGPVGPRGDPGAPGLPGPPG--- 982
                    G PGL G PG  G +G +G    AG +G PGP G  GD G  G PGPPG   
Sbjct: 679  PGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIG 738

Query: 983  ----------KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE-----NCALGGQC----V 1023
                       G DG PG  G PG  GP G +   G+V G++     +  + GQ     +
Sbjct: 739  PRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGL 798

Query: 1024 KGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082
             GDRG PG  GS G  G PG+ G  G PGPSG PG  G PG  G PG PG +GP G  G 
Sbjct: 799  PGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGI 858

Query: 1083 PGN---PGERGPPGKPGLSSLLSPGDINL--LAKDVCNDCPPGPPGLPGLPGFKGDKGVP 1137
            PG    PG+RG PG  G     +PG + +  L+ D  +    G  G PG PGFKG  G+P
Sbjct: 859  PGREGLPGDRGDPGDTG-----APGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMP 913

Query: 1138 GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP 1197
            G PG +G  G  G  G  G+PG  G  G  GS+GE G  G  G KG  G PG  G  G P
Sbjct: 914  GTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDP 973

Query: 1198 GNPGPP-----------GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK-E 1245
            G PGPP           G  G  G  G  G  G+ G +G PG  G SG+PG+PG  G  +
Sbjct: 974  GPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIK 1033

Query: 1246 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP---------------- 1289
            G  G  G PG PG  G PG+ GP G  G PGF G  GD GAPG                 
Sbjct: 1034 GVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDI 1093

Query: 1290 ------------RGESGAMGLPGQEGL------------PGKDGDTGPTGPQGPQGPRGP 1325
                        +GE G  G+PG +G             PG  G TG  GP G +G  G 
Sbjct: 1094 GDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGF 1153

Query: 1326 PGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF---LGPRGPPGEPGEKGVPGKEG- 1381
            PG  G PGS GE G  G PG KG  G  G+PGLPGF    G RG  G PG KG PG  G 
Sbjct: 1154 PGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGS 1213

Query: 1382 -VPGKPGEPGFKGERGDPGI-------------KGDKGPPGGKGQPGDPGIPGHKGHTGL 1427
             + G PG PG  GERGDPG              KGD+G PG +G PG PG+ G  G T  
Sbjct: 1214 DIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPP 1273

Query: 1428 MGPQGLPGENGPVG---------PPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLET 1478
                G PG+ G  G         PPGPPG    PG +G++ +                  
Sbjct: 1274 SNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPG---------------- 1317

Query: 1479 RLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPK 1538
                  A   P   K   G  GP G PG  GLPG  GP GE G  G  G  G  G  GPK
Sbjct: 1318 ------APGTPG-TKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPK 1370

Query: 1539 GERGAKGDPGAPG--------------------VGLRGEMGPPGIPGQ------PGEPGY 1572
            G +G  G PGAPG                    VG +G  GPPG PG+      PGEPG+
Sbjct: 1371 GPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGF 1430

Query: 1573 AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607
               G PG  GPQG  G +  PG  G  GP G   P
Sbjct: 1431 R--GAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGP 1463



 Score =  820 bits (2119), Expect = 0.0
 Identities = 560/1394 (40%), Positives = 642/1394 (46%), Gaps = 282/1394 (20%)

Query: 476  CSC--PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKG 533
            C C    G +G+ G  GP G  GP G  G  G  G  G KGE+G  G+     G KG+ G
Sbjct: 51   CQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGV----TGPKGDVG 106

Query: 534  SLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERG 593
            + G+ G PG DG  G  G+ G  G PG  G  G +G  GP G PG  G  G PG QG +G
Sbjct: 107  ARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKG 166

Query: 594  EKGT------------RGEKGERGLDGF---PGKPGDTGQQ------GRPGPSGVAGP-- 630
            +KG             RGE GE GL GF   PG+PG  GQ       GRPGP G  GP  
Sbjct: 167  QKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKG 226

Query: 631  ------------QGEKGDVGPAGPPGVPGSVV--------------QQEGLKGEQGAPGP 664
                        +GEKGDVG  GP G+P   +              Q +G KG +G PG 
Sbjct: 227  QQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGI 286

Query: 665  R-----GHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPP 719
            R     G +G  G PG RG  G  G  G PG +G RG  G  GP G  G  G  G PGPP
Sbjct: 287  RGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP 346

Query: 720  GV----------------PGPPGPGGSPGLPGEIGFPGKPGPPGPT-------------- 749
            G+                PG PG  G PG  GE G PG PGPPG +              
Sbjct: 347  GLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEM 406

Query: 750  ----------------GPPGKDGPNGPPGPPGTKGEP----------GERGEDGLPGKPG 783
                            GPPG DG  GPPGPPG  G P          G +G  G PG PG
Sbjct: 407  GPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPG 466

Query: 784  LRGEIGEQGLAGRPGE----------KGEAGLPGAPGFPGVRGE---KGDQGEKGELGLP 830
              G  G +G  G  GE          KG  GLPG  GF G+ GE   KGD+G+ G+ GLP
Sbjct: 467  SPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLP 526

Query: 831  GLKGDRGEKGEAGPAGP------------------PGLPGTTSL--------------FT 858
            G  G +G  G  G  GP                  PG+PG   +              F 
Sbjct: 527  GFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFP 586

Query: 859  PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP 918
              P  PG+ G KG  GDPG PG PG +G PGE+GP G  G PG KGQ    G PG AG P
Sbjct: 587  GLPGPPGD-GIKGPPGDPGYPGIPGTKGTPGEMGPPG-LGLPGLKGQ---RGFPGDAGLP 641

Query: 919  GAPGHVGAPGPSGPPGSV---------------------------GAPGLRGTPGKDGER 951
            G PG +G PGP+G PG +                           G PGL G PG  G +
Sbjct: 642  GPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAK 701

Query: 952  GEKGA---AGEEGSPGPVGPRGDPGAPGLPGPPG-------------KGKDGEPGLRGSP 995
            G +G    AG +G PGP G  GD G  G PGPPG              G DG PG  G P
Sbjct: 702  GLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLP 761

Query: 996  GLPGPLGTKAACGKVRGSE-----NCALGGQ----CVKGDRGAPGIPGSPGSRGDPGI-G 1045
            G  GP G +   G+V G++     +  + GQ     + GDRG PG  GS G  G PG+ G
Sbjct: 762  GPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKG 821

Query: 1046 VAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGN---PGERGPPGKPGLSSLLS 1102
              G PGPSG PG  G PG  G PG PG +GP G  G PG    PG+RG PG  G     +
Sbjct: 822  QPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTG-----A 876

Query: 1103 PGDINL--LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160
            PG + +  L+ D  +    G  G PG PGFKG  G+PG PG +G  G  G  G  G+PG 
Sbjct: 877  PGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGL 936

Query: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPP-----------GADGIA 1209
             G  G  GS+GE G  G  G KG  G PG  G  G PG PGPP           G  G  
Sbjct: 937  KGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDE 996

Query: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK-EGRDGKPGPPGEPGKAGEPGLPGP 1268
            G  G  G  G+ G +G PG  G SG+PG+PG  G  +G  G  G PG PG  G PG+ GP
Sbjct: 997  GPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGP 1056

Query: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMG-------------LPGQEGLPGKDGDTGPTG 1315
             G  G PGF G  GD GAPG  G  G +G             LPG+ GL G+ G TG  G
Sbjct: 1057 PGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPG 1116

Query: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375
             +G  G +G  G  G PG  G  G  G PG KG  G  G  G PG  G  G  G PG KG
Sbjct: 1117 LKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKG 1176

Query: 1376 VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP--GDPGIPGHKGHTG------- 1426
              G  G PG PG PG +G RG  G+ G KG PG  G    GDPG PG  G  G       
Sbjct: 1177 DDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANT 1236

Query: 1427 LMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQ 1486
            L GP G+PG+ G  G PG  G PG PGL+G  P +     +      K           +
Sbjct: 1237 LPGPVGVPGQKGDQGAPGERGPPGSPGLQG-FPGITPPSNISGAPGDKGAPGIFGLKGYR 1295

Query: 1487 MPP-----AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
             PP     A +  S+G  G PG PG  G  G AG  G  GRPG  GL G  GP G +G  
Sbjct: 1296 GPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFM 1355

Query: 1542 GAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-YAKDGLPGIP----------GPQGETGPA 1590
            G  G  GA  VG RG  GP G PG PG PG     G+ GIP          GPQG  GP 
Sbjct: 1356 GNTGPTGA--VGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPP 1413

Query: 1591 GHPGLPGPPGPPGQ 1604
            G PG  GP GPPG+
Sbjct: 1414 GAPGEMGPQGPPGE 1427



 Score =  757 bits (1955), Expect = 0.0
 Identities = 511/1293 (39%), Positives = 605/1293 (46%), Gaps = 258/1293 (19%)

Query: 542  GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEK 601
            GRD S G +  P + G        G  GP GP G  GPPG  G PGLQG +G+KG     
Sbjct: 44   GRDCSGGCQCYPEKGGR-------GQPGPVGPQGYNGPPGLQGFPGLQGRKGDKG----- 91

Query: 602  GERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661
             ERG  G  G  GD G +G  G  G  G  G  G  GP G PG  G      G +G+ G 
Sbjct: 92   -ERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGC----NGTQGDSGP 146

Query: 662  PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721
             GP G +G  GPP   GP GP+G+ G P       +    G PG PGL+G QGPPG PG 
Sbjct: 147  QGPPGSEGFTGPP---GPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGH 203

Query: 722  PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPP--GPPGTKGEPGERGEDGLP 779
             G  GP         +G PG+PGPPGP GP G+ G  G    G  G KG+ G+ G +G+P
Sbjct: 204  VGQMGP---------VGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIP 254

Query: 780  ---------------------GKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEK 818
                                 G+ G  GE G +G++ + GE+G  G PG  G+PG+ GEK
Sbjct: 255  SDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLK-GEEGIMGFPGLRGYPGLSGEK 313

Query: 819  GDQGEKGELGLPGLKGD---RGEKGEAGPAGPPGLPGTTSLFTPHPRMP----------- 864
            G  G+KG  GL G +G    RG KGEAG  GPPGLP     ++PHP +            
Sbjct: 314  GSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPA----YSPHPSLAKGARGDPGFPG 369

Query: 865  --GEQGPKGEKGDPGLPGEPGL--------QGRPGELGPQGPTGPPGAKGQEGAHGAPGA 914
              GE G +GE GDPGLPG PGL        +G PGE+GP+G  G PG     G  G PG 
Sbjct: 370  AQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYG--GPPGP 427

Query: 915  AGNPGAPGHVGAPGPSGPPGSV----------GAPGLRGTPGKDGERGEKGAAGE----- 959
             G  G PG  G PGP GP G +          G PGL G+PG  G +G KG AGE     
Sbjct: 428  DGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTE 487

Query: 960  -----EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014
                 +G PG  GP+G  G  G PG   KG  G+PG  G PG PG  G     G   G +
Sbjct: 488  GDEAIKGLPGLPGPKGFAGINGEPGR--KGDRGDPGQHGLPGFPGLKGVPGNIG-APGPK 544

Query: 1015 NCALGGQCV--KGDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGD--KGSPGSRG 1066
                  + +  KG+RG PG+PG PG +GD G     G+ G PG  GPPGD  KG PG  G
Sbjct: 545  GAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPG 604

Query: 1067 LPGFPGPQGPAGRDGAPGN-----------PGERGPPGKPGLSSLLSP------------ 1103
             PG PG +G  G  G PG            PG+ G PG PG      P            
Sbjct: 605  YPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTD 664

Query: 1104 ------GDINLLAKDVCNDCPPGPPGLPG------------LPGFKGDKGVPGKPGREGT 1145
                  GD     +  C   P G PGLPG            +PGF G  G PG  G  G 
Sbjct: 665  VKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGD 724

Query: 1146 EGKKGEAGPPGL------------------PGPPGIAGPQGSQGERGADGEV-----GQK 1182
             G++G  GPPG                   PGP G+ GP G  GERG  GEV     G +
Sbjct: 725  AGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPR 784

Query: 1183 GDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP---------------- 1226
            GD G PG PG  G PG+ GPPG  G  G  G PG++G PG  GP                
Sbjct: 785  GDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFP 844

Query: 1227 --PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG------------------KAGEPGLP 1266
              PG +GP GLPGIPG EG  G  G PG  G PG                  + G PG P
Sbjct: 845  GAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSP 904

Query: 1267 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 1326
            G +G  G PG  G  GD G+PG  G  G  GL G+ G PG  G+ G  G  G +G  G P
Sbjct: 905  GFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEP 964

Query: 1327 GKNGSPGSPGEPGPSGT--PGQK---GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 1381
            G  GS G PG PGP     PG K   G KG+ G  GL G+LG +G  G PG   +PG  G
Sbjct: 965  GFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPG---IPGLSG 1021

Query: 1382 VPGKPGEPG-FKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440
            +PG PG PG  KG +GD G+ G  G PG  G  G PGI G  G  G  G +G PG  G  
Sbjct: 1022 IPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLY 1081

Query: 1441 GPPGPPGQ----------PGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLA--- 1485
            G  G  G           PG PGL+GE  +  +  L+    E+ G + +     +     
Sbjct: 1082 GEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEK-GTEGDIGFPGITGVTG 1140

Query: 1486 -QMPPAYMKSSQGRPGPPGPPGKDG------LPGRAGPMGEPGRPGQGGLEGPSGPIGPK 1538
             Q PP  +K   G PG  GPPG  G      LPG  G  G PG PG  G  G  G  G  
Sbjct: 1141 VQGPPG-LKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLH 1199

Query: 1539 GERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD-----GLPGIPGPQGETGPAGHP 1593
            G  G KG PG+PG  + G+ G PG PG+ G+PG A       G+PG  G QG  G  G P
Sbjct: 1200 GLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPP 1259

Query: 1594 GLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626
            G PG  G PG   PS      +++  PG+   P
Sbjct: 1260 GSPGLQGFPGITPPS------NISGAPGDKGAP 1286



 Score =  747 bits (1928), Expect = 0.0
 Identities = 493/1185 (41%), Positives = 570/1185 (48%), Gaps = 209/1185 (17%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG-DIG----AI 504
            +P PP  P   P P   + G           GE G  G  G  GLPGP G  IG      
Sbjct: 342  DPGPPGLPAYSPHPSLAK-GARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRR 400

Query: 505  GPVGAPGPKGEKGDVGI-----GPFG-QGEKGEKGSLGLPGPPGRDGSK-GMRGEPGELG 557
            G  G  GPKG  GD GI     GP G  G++G  G  GLPGPPG DG   G++G  G  G
Sbjct: 401  GLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAG 460

Query: 558  EPGLPGEVGMRGPQG----------------PPGLPGPPGRVGAPGLQGERGEKGTRGEK 601
             PGLPG  G RGP+G                  GLPG PG  G  G+ GE G KG RG+ 
Sbjct: 461  FPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDP 520

Query: 602  GERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGA 661
            G+ GL GFPG  G  G  G PGP G  G        G  G PGVPG      G+KG+ G+
Sbjct: 521  GQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGV----PGMKGDDGS 576

Query: 662  PGPRGHQGAPGPPGARGP--IGPEGRDGPPGLQGLRGKKGDMGPPGI--PGLLGLQGPPG 717
            PG  G  G PG PG  G    GP G  G PG+ G +G  G+MGPPG+  PGL G +G PG
Sbjct: 577  PGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPG 636

Query: 718  PPGVPGPPG---PGGSPGLPGEIGF-----------------PGKPGPPGPTGPPGKDGP 757
              G+PGPPG   P G  G PG+I                   PG  G  GP G PG  GP
Sbjct: 637  DAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIG--GPKGLPGLPGP 694

Query: 758  NGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG------EKGEAGLPGAPGF 811
             GP G  G +G PG  G DG PG  GL G+ G +G  G PG       KG  GLPG  G 
Sbjct: 695  PGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGS 754

Query: 812  PGVRGEKGDQGEKGELGLPG--LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 869
            PG  G  G  G  GE GLPG  L    G +G+AG  G PGL G          +PG++GP
Sbjct: 755  PGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKG----------LPGDRGP 804

Query: 870  KGEKGDPGLPGEPGLQGRPGELGPQGPTG---PPGAKGQEGAHGAPGAAGNPGAPGHVGA 926
             G +G  G+PG PGL+G+PG  GP G  G   PPG  G  GA G  G  G PG PG  G 
Sbjct: 805  PGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGL 864

Query: 927  PGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGK--- 983
            PG  G PG  GAPG  G  G  G+RG+ G  GE+G PG  G +G  G PG PG  G    
Sbjct: 865  PGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGS 924

Query: 984  ----GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP--- 1036
                G  G PGL+G PG PG  G     G + G +  A G    KG RG PG PG P   
Sbjct: 925  PGMDGFQGMPGLKGRPGFPGSKGEAGFFG-IPGLKGLA-GEPGFKGSRGDPGPPGPPPVI 982

Query: 1037 --------GSRGD------------------PGI-GVAGPPGPSGPPG-------DKGSP 1062
                    G +GD                  PGI G++G PG  G PG       D G P
Sbjct: 983  LPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDIGVP 1042

Query: 1063 GSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL----SPGDINLLAKDVCNDCP 1118
            G  GLPGFPG  GP G  G PG  G RG  G PG + L     + GD   +   +     
Sbjct: 1043 GIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGR 1102

Query: 1119 PG------PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP---PGIAGPQGS 1169
            PG        G+PGL GF G+KG  G  G  G  G  G  GPPGL G    PG+ GP GS
Sbjct: 1103 PGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGS 1162

Query: 1170 QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG-----IQGSPGKE 1224
            QGE G  G  G KGD G PG PG  G PG  G  G  G+ G  G PG     I G PG  
Sbjct: 1163 QGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFP 1222

Query: 1225 GPPGPQGPSG----LPG---IPGEEGKEGRDGKPGPPGEPGKAGEPGL------------ 1265
            GPPG +G  G    LPG   +PG++G +G  G+ GPPG PG  G PG+            
Sbjct: 1223 GPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAPGD 1282

Query: 1266 ---------------PGPEGARGPPGFKGHTGDSGAPG------------PRGESGAMGL 1298
                           PGP G+   PG KG TG+ GAPG            P+G  G  GL
Sbjct: 1283 KGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGL 1342

Query: 1299 PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPG-----QK------ 1347
            PG++G  G+ G  G TGP G  G RGP G  G PG PG PG  G PG     QK      
Sbjct: 1343 PGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPG 1402

Query: 1348 --GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE---PGFKGERGDPGIKG 1402
              G +G  G PG PG +GP+GPPGEPG +G PGK G  G+ G    PGF+G+ G  G +G
Sbjct: 1403 TVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQG 1462

Query: 1403 ---DKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPG 1444
                +G PG  G PG PG+PG     G +  +    +  P+ P G
Sbjct: 1463 PIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVG 1507



 Score =  734 bits (1895), Expect = 0.0
 Identities = 493/1230 (40%), Positives = 570/1230 (46%), Gaps = 267/1230 (21%)

Query: 456  PPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGA---------IGP 506
            P Q     GSE    ++ I+     G  G  G+ G  GL G KG  G           GP
Sbjct: 271  PDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGP 330

Query: 507  VGAPGPKGEKGDVGIG---------------------PFGQGE---KGEKGSLGLPGPPG 542
             G  GPKGE GD G                       P  QGE   +GE G  GLPGPPG
Sbjct: 331  DGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPG 390

Query: 543  --------RDGSKGMRGEPGELGEPGL-------PGEVGMRGPQGPPGLPGPP------- 580
                    R G  G  G  G +G+PG+       PG  G RGP GPPGLPGPP       
Sbjct: 391  LSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLF 450

Query: 581  ------GRVGAPGLQGERGEKGTRGEKGE-------RGLDGFPGKPGDTGQQGRPGPSGV 627
                  GR G PGL G  G +G +G KG+        G +   G PG  G +G  G +G 
Sbjct: 451  GLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGE 510

Query: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP---------------RGHQGAPG 672
             G +G++GD G  G PG PG     +G+ G  GAPGP               RG  G PG
Sbjct: 511  PGRKGDRGDPGQHGLPGFPG----LKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPG 566

Query: 673  PPGARGPIGPEGRDGPPGLQGLRGKKGD--MGPPGIPGLLGLQGPPGPPGVPGPPGPGGS 730
             PG +G  G  GRDG  G  GL G  GD   GPPG PG  G+ G  G PG  GPPG  G 
Sbjct: 567  VPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGL-GL 625

Query: 731  PGLPGEIGFPGK---PGPPGPTGPPGKDGP---------------------------NGP 760
            PGL G+ GFPG    PGPPG  GPPG  G                             GP
Sbjct: 626  PGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGP 685

Query: 761  PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEK-- 818
             G PG  G PG  G  GL G PG  G  G  G  G PG+ G  G PG PGF G RG K  
Sbjct: 686  KGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGA 745

Query: 819  ----GDQGEKGELGLPGLKGDRGEKG--------EAGPAGPPGLPGTTSLFTPHPRMPGE 866
                G  G  G +GLPG  G  GE+G        + GP G  G+PG   L      +PG+
Sbjct: 746  VGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGL----KGLPGD 801

Query: 867  QGPKGEKGDPGLPGEPGLQGRPGELGPQGPT---GPPGAKGQEGAHGAPGAAGNPGAPGH 923
            +GP G +G  G+PG PGL+G+PG  GP G     GPPG  G  GA G  G  G PG PG 
Sbjct: 802  RGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGR 861

Query: 924  VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG---- 979
             G PG  G PG  GAPG  G  G  G+RG+ G  GE+G PG  G +G  G PG PG    
Sbjct: 862  EGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGD 921

Query: 980  ---PPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036
               P   G  G PGL+G PG PG  G     G + G +  A G    KG RG PG PG P
Sbjct: 922  RGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFG-IPGLKGLA-GEPGFKGSRGDPGPPGPP 979

Query: 1037 -----------GSRGD------------------PGI-GVAGPPGPSGPP-------GDK 1059
                       G +GD                  PGI G++G PG  G P       GD 
Sbjct: 980  PVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDI 1039

Query: 1060 GSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL----SPGDINLLAKDVCN 1115
            G PG  GLPGFPG  GP G  G PG  G RG  G PG + L     + GD   +   +  
Sbjct: 1040 GVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINL 1099

Query: 1116 DCPP------GPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP---PGIAGP 1166
               P      G  G+PGL GF G+KG  G  G  G  G  G  GPPGL G    PG+ GP
Sbjct: 1100 PGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGP 1159

Query: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG-----IQGSP 1221
             GSQGE G  G  G KGD G PG PG  G PG  G  G  G+ G  G PG     I G P
Sbjct: 1160 PGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDP 1219

Query: 1222 GKEGPPGPQGPSG----LP---GIPGEEGKEGRDGKPGPPGEPGKAGEPGL--------- 1265
            G  GPPG +G  G    LP   G+PG++G +G  G+ GPPG PG  G PG+         
Sbjct: 1220 GFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGA 1279

Query: 1266 ------------------PGPEGARGPPGFKGHTGDSGAP------------GPRGESGA 1295
                              PGP G+   PG KG TG+ GAP            GP+G  G 
Sbjct: 1280 PGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGV 1339

Query: 1296 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPG-----QK--- 1347
             GLPG++G  G+ G  G TGP G  G RGP G  G PG PG PG  G PG     QK   
Sbjct: 1340 FGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAV 1399

Query: 1348 -----GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPG---EPGFKGERGDPG 1399
                 G +G  G PG PG +GP+GPPGEPG +G PGK G  G+ G    PGF+G+ G  G
Sbjct: 1400 QPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIG 1459

Query: 1400 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMG 1429
             +G  G  G  G+PG PG+PG  G +  +G
Sbjct: 1460 HQGPIGQEGAPGRPGSPGLPGMPGRSVSIG 1489



 Score =  537 bits (1383), Expect = e-152
 Identities = 375/953 (39%), Positives = 433/953 (45%), Gaps = 214/953 (22%)

Query: 481  GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVG----IGPFGQGEKGEKGSLG 536
            G  G  G+ G  GLPGP GD G  GP G PG  G  G  G    +GP G G  G KG  G
Sbjct: 575  GSPGRDGLDGFPGLPGPPGD-GIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRG 633

Query: 537  LPGPPGRDGSKGMRGEPGELGEPGL--------------------PGEVGMRGPQGPPGL 576
             PG  G  G  G  G PG  G PG                     PG +G  GP+G PGL
Sbjct: 634  FPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIG--GPKGLPGL 691

Query: 577  PGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGD 636
            PGPPG  GA GL+G  G  G  G  G RGL      PGD G++G PGP G  GP+G KG 
Sbjct: 692  PGPPGPTGAKGLRGIPGFAGADGGPGPRGL------PGDAGREGFPGPPGFIGPRGSKGA 745

Query: 637  VGPAGPPGVPGSV--VQQEGLKGEQGAPG--------PRGHQGAPGPPGA------RGPI 680
            VG  GP G PG +     +G  GE+G PG        PRG  G PG PG       RGP 
Sbjct: 746  VGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPP 805

Query: 681  GPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP 740
            G  G  G PG+ GL+G+ G  GP G PGL G  G  G PG PG  GP G PG+PG  G P
Sbjct: 806  GFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLP 865

Query: 741  GKPGPPGPTGPPGKDGPNGPPGPPGTKG---------EPGERGEDGLPGKPGLRGEIGEQ 791
            G  G PG TG PG  G  G  G  G  G          PG +G DG+PG PGL+G+ G  
Sbjct: 866  GDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSP 925

Query: 792  GL------------AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG--------LPG 831
            G+             G PG KGEAG  G PG  G+ GE G +G +G+ G        LPG
Sbjct: 926  GMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPG 985

Query: 832  LKGDRGEKGEAGPAG------------PPGLPGTTSLFTPHPRMPGEQGP-KGEKGDPGL 878
            +K  +GEKG+ GP G             PG+PG + +    P +PG  G  KG KGD G+
Sbjct: 986  MKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGI----PGLPGRPGHIKGVKGDIGV 1041

Query: 879  PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVG------------- 925
            PG PGL G PG  GP G TG PG  G  G  GAPG AG  G  G  G             
Sbjct: 1042 PGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPG 1101

Query: 926  APGPSGPPGSVGAPGLRGTPGKDGERGE---KGAAGEEGSPGPVGPRGDPGAPGLPGPPG 982
             PG  G  G+ G PGL+G  G+ G  G+    G  G  G  GP G +G  G PGL GPPG
Sbjct: 1102 RPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPG 1161

Query: 983  -------------KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGA 1029
                         KG DG PG  G PG PG  G +   G           G  + GD   
Sbjct: 1162 SQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGD--- 1218

Query: 1030 PGIPGSPGSRGDPG--------IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081
            PG PG PG RGDPG        +GV G  G  G PG++G PGS GL GFPG   P+   G
Sbjct: 1219 PGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISG 1278

Query: 1082 APGNPGE---------RGPPGKPGLSSLL-SPGDINLLA-------KDVCNDC-PPGPPG 1123
            APG+ G          RGPPG PG ++L  S GD            K    D  P G PG
Sbjct: 1279 APGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPG 1338

Query: 1124 LPGLPGFKG---------------------------DKGVPGKPG--------------- 1141
            + GLPG KG                           D G PG PG               
Sbjct: 1339 VFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIA 1398

Query: 1142 -REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP---- 1196
             + GT G +G  GPPG PG  G  GP G  G RGA G+ G +G  G   VPGF G     
Sbjct: 1399 VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI 1458

Query: 1197 --------------PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL 1235
                          PG+PG PG  G + + G   ++ S   + P  P G + L
Sbjct: 1459 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGMNKL 1511



 Score =  483 bits (1243), Expect = e-136
 Identities = 348/937 (37%), Positives = 411/937 (43%), Gaps = 226/937 (24%)

Query: 899  PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG 958
            P G +   G        G  G PG VG  G +GPPG  G PGL+G  G  GERG  G  G
Sbjct: 41   PCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTG 100

Query: 959  EEGSPGPVGPRGDPGAPGLPGPPGK-------------------GKDGEPGLRGSPGLPG 999
             +G  G  G  G PGA G+PG PG+                   G  G PG  G  G PG
Sbjct: 101  PKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPG 160

Query: 1000 PLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG----------IGVAGP 1049
            P G K   G     E  AL  +     RG PG PG  G +G PG          +G  G 
Sbjct: 161  PQGPKGQKG-----EPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGR 215

Query: 1050 PGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG------------------------N 1085
            PGP GPPG KG  G+RGL GF G +G  G  G PG                         
Sbjct: 216  PGPPGPPGPKGQQGNRGL-GFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQY 274

Query: 1086 PGERGPPGKPGLSSLLSPGDINLLAKDVCN--------------------------DCPP 1119
             GE+G  G+PG+  +   G+  ++                                D P 
Sbjct: 275  KGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPR 334

Query: 1120 GP------PGLPGLPGF-------KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166
            GP      PG PGLP +       KG +G PG PG +G  G +GE G PGLPGPPG++  
Sbjct: 335  GPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIG 394

Query: 1167 QGSQGERGADGEVGQKGDQGHPGVP-------------GFMGPPGNPGPPGADGI----- 1208
             G Q  RG  GE+G KG  G PG+P             G  GPPG PGPPG DG      
Sbjct: 395  DGDQ-RRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLK 453

Query: 1209 --AGAAGPPGIQGSPGKEGPPGPQGPS-------------GLPGIPGEEGKEGRDGKPGP 1253
               G AG PG+ GSPG  GP G +G +             GLPG+PG +G  G +G+PG 
Sbjct: 454  GAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGR 513

Query: 1254 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG------PRGESGAMGLPGQEGLPGK 1307
             G+ G  G+ GLPG  G +G PG  G  G  GA G       +GE G  G+PG  G+ G 
Sbjct: 514  KGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGD 573

Query: 1308 DGDTGPTGPQGPQGPRGPPGKN-----GSPGSPGEPGPSGTP--------------GQKG 1348
            DG  G  G  G  G  GPPG       G PG PG PG  GTP              GQ+G
Sbjct: 574  DGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRG 633

Query: 1349 SKGENGSPGLPGFLGPRGPPGEPGE------------------------KGVPGKEGVPG 1384
              G+ G PG PGFLGP GP G PG+                         G  G  G+PG
Sbjct: 634  FPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPG 693

Query: 1385 KPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ------GLPGEN- 1437
             PG  G KG RG PG  G  G PG +G PGD G  G  G  G +GP+      GLPG + 
Sbjct: 694  PPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDG 753

Query: 1438 --GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSS 1495
              GP+G PGP G PG  GL GE    +   R    + G   +  L  L     P   + S
Sbjct: 754  SPGPIGLPGPDGPPGERGLPGEVLGAQPGPR---GDAGVPGQPGLKGLPGDRGPPGFRGS 810

Query: 1496 QGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGP------------KGERGA 1543
            QG PG PG  G+ GLPG +G  G  G PG  G  G  G  GP             G+RG 
Sbjct: 811  QGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGD 870

Query: 1544 KGDPGAPG-VGL------RGEMGPPGIPGQPGEPGY-AKDGLPGIPGPQGETGP------ 1589
             GD GAPG VG+      RG+ G  G  G PG PG+   DG+PG PG +G+ G       
Sbjct: 871  PGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGF 930

Query: 1590 AGHPGLPGPPGPPGQCDPSQCAYFA-----SLAARPG 1621
             G PGL G PG PG     +  +F       LA  PG
Sbjct: 931  QGMPGLKGRPGFPG--SKGEAGFFGIPGLKGLAGEPG 965



 Score =  122 bits (306), Expect = 3e-27
 Identities = 88/224 (39%), Positives = 102/224 (45%), Gaps = 35/224 (15%)

Query: 1390 GFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQP 1449
            GF  +    G+K    P GG+   G       KG  G  GP G  G N      GPPG  
Sbjct: 25   GFLAQSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYN------GPPGLQ 78

Query: 1450 GFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG 1509
            GFPGL+G        R+  + E G    T          P     ++G  G PG  G  G
Sbjct: 79   GFPGLQG--------RKGDKGERGAPGVT---------GPKGDVGARGVSGFPGADGIPG 121

Query: 1510 LPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG-VGLRGEMGPPGIP---- 1564
             PG+ GP G PG  G  G +G SGP GP G  G  G PG  G  G +GE  P  +P    
Sbjct: 122  HPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGE--PYALPKEER 179

Query: 1565 ----GQPGEPGYAK-DGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
                G+PGEPG     G PG PG  G+ GP G PG PGPPGPPG
Sbjct: 180  DRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPG 223


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score =  820 bits (2119), Expect = 0.0
 Identities = 572/1395 (41%), Positives = 666/1395 (47%), Gaps = 291/1395 (20%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLP 538
            P G+KG MGV G +G+ G  G  G  GP G PG  G  G  G      G  G  G  GL 
Sbjct: 90   PKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQG----AVGFPGPDGYPGLL 145

Query: 539  GPPGRDGSKGMRGEP--------GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQG 590
            GPPG  G KG +G+P        G  G+PGLPG  G+ GPQG PG PG  G  G PGLQG
Sbjct: 146  GPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQG 205

Query: 591  ERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA-------------GPQGEKGDV 637
              G  G  G  G  GL GF G+ G  G  G PGP+G               G +G KG+ 
Sbjct: 206  PPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 264

Query: 638  GP------AGPPGVPG-SVVQQEGLKGEQGAPG------PRGHQGAPGPPGARGPIGPEG 684
            GP      +GPPG PG     ++G KGE+G PG      P G +G  GPPG +G  G  G
Sbjct: 265  GPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG 324

Query: 685  RDGPPGLQGLRGKKGDMG--------------------PPGIPGLLGL------QGPPGP 718
              G  G QG+ G+KGD+G                     PG+PGL GL      QG  GP
Sbjct: 325  FPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGP 384

Query: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGP---PGPT-----GPPGKDGPNGPPGPPGT---- 766
             GVPG P   G PG  G  GFPG  G    PG T     G PG+DG  GPPGPPG     
Sbjct: 385  SGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPE 444

Query: 767  ----------KGEPGERGEDGLPGKPGLRGEIGEQGLA------------GRPGEKGEAG 804
                       G PG RGE G  G  GL+G  G+ G              G PG  G  G
Sbjct: 445  FETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWG 504

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGL------------------------KGDRGEKG 840
            L G PG  G RG++G  G +G  G PGL                         GDRG+ G
Sbjct: 505  LIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSG 564

Query: 841  ---------EAGPAGPPGLPGTTSLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPG 889
                     E G  G PGLPG        P +PG+  QG  GEKG PGLPGE G  G PG
Sbjct: 565  SQGFRGVIGEPGKDGVPGLPGL-------PGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 617

Query: 890  ELGP--QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV------GAPGPSGPPGSVGAPG- 940
              G    G  GP G  G +G  G PG  G PG+ G        G+ GPSG PG+ G PG 
Sbjct: 618  LPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGP 677

Query: 941  --LRGTPGKDGERGEKGAAGEEGSPGPV---------GPRGDPGAPGLPGPPGKGKDGEP 989
               RG PG  G+ G  G+ GE GSPG V         GPRG+ G PG PG PGK  DG P
Sbjct: 678  KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK--DGLP 735

Query: 990  GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV------------------KGDRGAPG 1031
            G+ GSPGLPG   +K A G + G+EN A G Q +                  KG  G PG
Sbjct: 736  GMIGSPGLPG---SKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPG 792

Query: 1032 IPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGLPGFPG------PQGPAGRDG 1081
            + G  G RG PG    +G  G PG SGP G KG  G  G PGFPG       +G  G+ G
Sbjct: 793  LLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKG 852

Query: 1082 APGN------PGERGPPGKPGLSSLL-SPGDINLLAKDVCNDCP-----------PGPPG 1123
             PG+      PG +G PG PGL  L  SPG   +      +              PG PG
Sbjct: 853  PPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPG 912

Query: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKG---EAGPPGLPGPPGIAGPQ------------G 1168
            LPG+PG +G KG+PG  G+ G  G+ G   E G  G PGP GI  P+            G
Sbjct: 913  LPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKG 972

Query: 1169 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA-DGIAGAAGPPGIQGSPGKEGPP 1227
            SQG  G++G  G +GD+G  G PG  G PG PG PG   G++G  GPPG  G  G  G  
Sbjct: 973  SQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLK 1032

Query: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGE---PGKAGE-------PGLPGPEGARGPPGF 1277
            G  G +G PG+PGE G +G  G PG PG    PG  G+        G PGP+G  G  GF
Sbjct: 1033 GSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGF 1092

Query: 1278 KGHTGDSGA------PGPRGESGAMGLPGQEGLPG------------KDGDTGPTGPQGP 1319
            KG  G  G       PG +GE G +G+ G  GLPG            + G  G +G QG 
Sbjct: 1093 KGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGA 1152

Query: 1320 QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGEPGEKGVP 1377
             GP G PG  G  G PG PG  G  G  G+KG +G+PG  + G  GP G PG  GEKG P
Sbjct: 1153 IGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYP 1212

Query: 1378 GKE-GVPGKPGEPGFKGERGDPGIKGDKGPPGGKG---------QPGDPGIPGHKGHTGL 1427
            G   G PGKPG  G KG+RG PG++G  G PG  G         QPGDPG PG  G  G 
Sbjct: 1213 GIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGR 1272

Query: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 1487
             GP G PG  GP    G  G PGFPG+ G  P      + I    G   E  L  +  + 
Sbjct: 1273 PGPAGPPGPPGPSSNQGDTGDPGFPGIPG--PKGPKGDQGIPGFSGLPGELGLKGMRGE- 1329

Query: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG-------LEGPSGPIGPKGE 1540
             P +M  + G+ GPPG PG  G+ G+AGP G  G  G  G       ++ P GP+G  G 
Sbjct: 1330 -PGFM-GTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGI 1387

Query: 1541 RGAKG---DPGAPG-VGLRGEMGPPGIPGQ------PGEPGYAKD-GLPGIPGPQGETGP 1589
             G  G   DPGA G VGL+G  G PGIPG+      PG PG   D GLPG+ GP G  G 
Sbjct: 1388 DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGA 1447

Query: 1590 AGHPGLPGPPGPPGQ 1604
             G  G  G PG PGQ
Sbjct: 1448 PGQQGPFGMPGMPGQ 1462



 Score =  820 bits (2118), Expect = 0.0
 Identities = 582/1444 (40%), Positives = 684/1444 (47%), Gaps = 303/1444 (20%)

Query: 440  SGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG 499
            SG CQ          P P     P   Q GF  +   S   GE+G  G+ GP G  G KG
Sbjct: 37   SGSCQCFPEKGARGRPGPIGIQGPTGPQ-GFTGSTGLSGLKGERGFPGLLGPYGPKGDKG 95

Query: 500  DIGAIGPVGAPGPKGEKGDVG-IGPFG-QGEKGEKGSLGLP---------GPPGRDGSKG 548
             +G  G +G  G  G  G  G  GP G  G  G +G++G P         GPPG  G KG
Sbjct: 96   PMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKG 155

Query: 549  MRGEP--------GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600
             +G+P        G  G+PGLPG  G+ GPQG PG PG  G  G PGLQG  G  G  G 
Sbjct: 156  SKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGP 215

Query: 601  KGERGLDGFPGKPGDTGQQGRPGPSG-------------VAGPQGEKGDVGP------AG 641
             G  GL GF G+ G  G  G PGP+G               G +G KG+ GP      +G
Sbjct: 216  DGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISG 274

Query: 642  PPGVPG-SVVQQEGLKGEQGAP------GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGL 694
            PPG PG     ++G KGE+G P      GP G +G  GPPG +G  G  G  G  G QG+
Sbjct: 275  PPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGI 334

Query: 695  RGKKGDM--------------------GPPGIPGLLGL------QGPPGPPGVPGPP--- 725
             G+KGD+                    G PG+PGL GL      QG  GP GVPG P   
Sbjct: 335  EGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 394

Query: 726  ------GPGGSPGLPGEIGFPGK--------------PGPPGPTGPP------------- 752
                  GP G PGL G+ G PG+              PGPPGP GPP             
Sbjct: 395  GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE 454

Query: 753  -------GKDGPNGPPGPPGTKGEPG---------ERGEDGLPGKPGLRGEIGEQGLAGR 796
                   G+ GP G  G  G KG+ G           G  G PG PG  G IG  GL G 
Sbjct: 455  SGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 514

Query: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP------GLKGDRGEK---------GE 841
             G++G  G  G  G PG+ G  G  G KG+ G P      G+ GDRG+          GE
Sbjct: 515  RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGE 574

Query: 842  AGPAGPPGLPGTTSLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPG--ELGPQGPT 897
             G  G PGLPG        P +PG+  QG  GEKG PGLPGE G  G PG    G  G  
Sbjct: 575  PGKDGVPGLPGL-------PGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP 627

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHV------GAPGPSGPPGSVGAP---GLRGTPGKD 948
            GP G  G +G  G PG  G PG+ G        G+ GPSG PG+ G P   G RG PG  
Sbjct: 628  GPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTP 687

Query: 949  GERGEKGAAGEEGSPGPV---------GPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
            G+ G  G+ GE GSPG V         GPRG+ G PG PG P  GKDG PG+ GSPGLP 
Sbjct: 688  GQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP--GKDGLPGMIGSPGLP- 744

Query: 1000 PLGTKAACGKVRGSENCALGGQ------------------CVKGDRGAPGIPGSPGSRGD 1041
              G+K A G + G+EN A G Q                   +KG  G PG+ G  G RG 
Sbjct: 745  --GSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 802

Query: 1042 PG----IGVAGPPGPSGPPGDKGSPGSRGLPGF------PGPQGPAGRDGAPGN------ 1085
            PG    +G  G PG SGP G KG  G  G PGF      PG +G  G+ G PG+      
Sbjct: 803  PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 862

Query: 1086 PGERGPPGKPGLSSLL-SPGDINLLAKDVCNDCP-----------PGPPGLPGLPGFKGD 1133
            PG +G PG PGL  L  SPG   +      +              PG PGLPG+PG +G 
Sbjct: 863  PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGL 922

Query: 1134 KGVPGKPGREGTEGK---KGEAGPPGLPGPPGIAGP------------QGSQGERGADGE 1178
            KG+PG  G+ G  G+    GE G  G PGP GI  P            +GSQG  G++G 
Sbjct: 923  KGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGF 982

Query: 1179 VGQKGDQGHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237
             G +GD+G  G PG  G PG PG PG   G++G  GPPG  G  G  G  G  G +G PG
Sbjct: 983  PGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPG 1042

Query: 1238 IPGEEGKEGRDGKPGPPGE---PGKAGE-------PGLPGPEGARGPPGFKGH------T 1281
            +PGE G +G  G PG PG    PG  G+        G PGP+G  G  GFKG        
Sbjct: 1043 MPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLI 1102

Query: 1282 GDSGAPGPRGESGAMGLPGQEGLP------------GKDGDTGPTGPQGPQGPRGPPGKN 1329
            G+ G PG +GE G +G+ G  GLP            G+ G  G +G QG  GP G PG  
Sbjct: 1103 GNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLI 1162

Query: 1330 GSPGSPGEPGPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGEPGEKGVPG-KEGVPGKP 1386
            G  G PG PG  G  G  G+KG +G+PG  + G  GP G PG  GEKG PG   G PGKP
Sbjct: 1163 GPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKP 1222

Query: 1387 GEPGFKGERGDPGIKGDKGPPGG---------KGQPGDPGIPGHKGHTGLMGPQGLPGEN 1437
            G  G KG+RG PG++G  G PG           GQPGDPG PG  G  G  GP G PG  
Sbjct: 1223 GLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPP 1282

Query: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497
            GP    G  G PGFPG+ G  P      + I    G   E  L  +  +  P +M  + G
Sbjct: 1283 GPSSNQGDTGDPGFPGIPG--PKGPKGDQGIPGFSGLPGELGLKGMRGE--PGFM-GTPG 1337

Query: 1498 RPGPPGPPGKDGLPGRAGPMGEPGRPGQGG-------LEGPSGPI---GPKGERGAKGDP 1547
            + GPPG PG  G+ G+AGP G  G  G  G       ++ P GP+   G  G  G  GDP
Sbjct: 1338 KVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDP 1397

Query: 1548 GAPG-VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP---GPPG 1603
            GA G VGL+G  G PGIPG        KDG  G+PGP G  G  G PGL GPP   G PG
Sbjct: 1398 GAQGPVGLQGSKGLPGIPG--------KDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPG 1449

Query: 1604 QCDP 1607
            Q  P
Sbjct: 1450 QQGP 1453



 Score =  800 bits (2066), Expect = 0.0
 Identities = 526/1272 (41%), Positives = 618/1272 (48%), Gaps = 200/1272 (15%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            EP P   P     PG   +G           GEKGE G  G  GLPGP+G +G+ G  G 
Sbjct: 263  EPGPKGFPGISGPPGFPGLG---------TTGEKGEKGEKGIPGLPGPRGPMGSEGVQGP 313

Query: 510  PGPKGEKGDVGIGPFG--QGEKGEKGSLGLPGPP---GRDGSKGMRGEPGELGEPGLPGE 564
            PG +G+KG +G       QG +G+KG +GLPGP      DG+  + G PG+ G PGLPG 
Sbjct: 314  PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV-ISGNPGDPGVPGLPGL 372

Query: 565  VG------MRGPQGPPGLP---GPPGRVGA---PGLQGERGEKG--TRGEKGERGLDGFP 610
             G      +RGP G PGLP   G PG +G    PGL+G++G  G  T G  G  G DG P
Sbjct: 373  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 432

Query: 611  GKPGDTGQ--------------------QGRPGPSGVAGPQGEKGD------------VG 638
            G PG  G                     +G  GP G  G +G KGD             G
Sbjct: 433  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 492

Query: 639  PAGPPGVPG--SVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG------ 690
            P G PG PG   ++   GLKG +G  G  G QG  G PG  GP+GP G  G  G      
Sbjct: 493  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 552

Query: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG-PG-GSPGLPGEIGFPGKPGPPGP 748
            +QG+ G +GD G  G  G++G  G  G PG+PG PG PG G  G PGE G PG PG  G 
Sbjct: 553  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 612

Query: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK---------------PGLRGEIGEQGL 793
             GPPG  G NG PG PG +G PG++G+DGLPG+               PG  G  G  G 
Sbjct: 613  PGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 671

Query: 794  AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 853
             G PG KG  GLPG PG PG  G KG+ G  G + LP L G  G +GE G  G PGLPG 
Sbjct: 672  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 731

Query: 854  TSL--FTPHPRMPGEQGPKGE--KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG----- 904
              L      P +PG +G  G+    + G PGE GLQG  G  G  G +G PG KG     
Sbjct: 732  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 791

Query: 905  ----QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
                 +G  G+PG  G  G PG  G+ GP G  G  G PG  G PG  G  G+KG  G++
Sbjct: 792  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 851

Query: 961  GSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 1016
            G PG +  +G PG  GLPG PG    KG  G PG+ G P L GP G K + G V      
Sbjct: 852  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 911

Query: 1017 ALGGQCVKGDRGAPGIPGSPGSRGDPGI-------GVAGPPGPSGPP------------G 1057
             L G  + G RG  GIPGS G  G  G        G  G PGP G P            G
Sbjct: 912  GLPG--IPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKG 969

Query: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS--PGDINLLAKDVCN 1115
            DKGS GS G  GFPGP+G  G  G PG PG  G PG PG+   +S  PG           
Sbjct: 970  DKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPG----------- 1018

Query: 1116 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE--- 1172
              PPG  G+ GLPG KG  G+ G PG  G  G +G  G PGLPG  G+ G +G  G+   
Sbjct: 1019 --PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVE 1076

Query: 1173 -------RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG--- 1222
                   +G  GE G KG +G  G+ G +G PGN G  G  G++G  G PG  G PG   
Sbjct: 1077 ISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1136

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG--FKGH 1280
              G PG  G SG  G  G  G  G  G  G PG PG  G  GLPG +G  G PG    G 
Sbjct: 1137 MRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGV 1196

Query: 1281 TGDSGAPGPRGESG----AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336
             G +G PGP+GE G     +G PG+ GL G+ GD G  G QGP G  G PG +      G
Sbjct: 1197 PGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAG 1256

Query: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
            +PG    PG+ G  GE G PG      P GPPG PG     G  G PG PG PG KG +G
Sbjct: 1257 QPGD---PGRPGLDGERGRPG------PAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKG 1307

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456
            D GI G  G PG  G  G  G PG  G  G +GP G PG  G  G  GP G  G  G  G
Sbjct: 1308 DQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPG 1367

Query: 1457 ESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP 1516
            ++P+ E +                     Q+PP  +    G PG  G PG  G PG  GP
Sbjct: 1368 QTPTAEAV---------------------QVPPGPL----GLPGIDGIPGLTGDPGAQGP 1402

Query: 1517 MGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDG 1576
            +G  G  G  G+ G  GP G  G  GA GDPG PG+      GPPG  G PG+ G    G
Sbjct: 1403 VGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGL-----QGPPGFEGAPGQQG--PFG 1455

Query: 1577 LPGIPGPQGETG 1588
            +PG+PG     G
Sbjct: 1456 MPGMPGQSMRVG 1467



 Score =  773 bits (1996), Expect = 0.0
 Identities = 524/1320 (39%), Positives = 612/1320 (46%), Gaps = 266/1320 (20%)

Query: 526  QGEKGEKGSLGLPGPPGRDG---SKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGR 582
            +G +G  G +G+ GP G  G   S G+ G  GE G PGL G  G +G +GP G+PG  G 
Sbjct: 46   KGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGI 105

Query: 583  VGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGP 642
             G PG  G+ G +G  G  G  G  G  G PG  G  G  GP G+ G +G KGD     P
Sbjct: 106  NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGD-----P 160

Query: 643  PGVPGSVVQQEGLKGEQGAPGP---RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKG 699
               PGS    +G+KG+ G PG     G QGAPG PGA GP GP G  GPPG  G  G  G
Sbjct: 161  VLAPGSF---KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 217

Query: 700  DMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI---GFP-GKPGPPGPTGPPGKD 755
            +MG       LG QG  G  G  G PGP G P   GE+   GFP GK G  G  GP G  
Sbjct: 218  NMG-------LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFP 270

Query: 756  GPNGPPGPPG--TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE---KGEAGLPGAPG 810
            G +GPPG PG  T GE GE+GE G+PG PG RG +G +G+ G PG+   KG  G PG  G
Sbjct: 271  GISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG 330

Query: 811  FPGVRGEKGD--------------------QGEKGELGLPGLKGDRGEKGEAGPAGPPGL 850
            F G+ G+KGD                     G+ G  GLPGLKGD G +G  GP+G PGL
Sbjct: 331  FQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGL 390

Query: 851  ------------------------PGTTSLFT---------------PHPRMP------- 864
                                    PG T++                 P P  P       
Sbjct: 391  PALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 450

Query: 865  -----------GEQGPKGEKGDPGLPGEPGL---------QGRPGELGPQGP---TGPPG 901
                       GEQGPKG  G  G+ G+ G           G PGE GP GP    G PG
Sbjct: 451  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 510

Query: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961
             KG  G  G+ GA G  GAPG VG  GPSGP G  G P L    G  G+RG+ G+ G  G
Sbjct: 511  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 570

Query: 962  SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021
              G  G  G PG PGLPG PG G  G PG +G PGLPG  G     G          G +
Sbjct: 571  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPR 630

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI-------GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074
             + GD+G  G+PG  G  G  GI       G  GP G  G PG  G  GSRGLPG PG  
Sbjct: 631  GLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQP 690

Query: 1075 GPAGRDGAPGNPG---------------ERGPPGKPGLSSLLSPGDINLLAKDVCNDCPP 1119
            G +G  G PG+PG               E+G PG PGL     PG   L          P
Sbjct: 691  GSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGL-----PGKDGL----------P 735

Query: 1120 GPPGLPGLPGFKG--------DKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171
            G  G PGLPG KG        + G PG+ G +G  G KG  G  GLPG  G+ G  G  G
Sbjct: 736  GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG 795

Query: 1172 ERGADGEVGQKGDQGHPGVPGFMGP---PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
             +G  G  G  G  G PG PG  GP    G  G PGA G  G +G PG +G+ GK+GPPG
Sbjct: 796  PKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPG 855

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG 1288
                 GLPG+ G  G  G  G  G PG PG AG P L GP+G +G  GF G  G  G PG
Sbjct: 856  SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG 915

Query: 1289 PRGESGAMGLPG---------QEGLPGKDGDTGPTGPQGPQGPRGP-------------- 1325
              G  G  G+PG         + G PG+ GD G  GP G   PR P              
Sbjct: 916  IPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQG 975

Query: 1326 -------PGKNGSPGSPGEPGPSGTPGQKGS----KGENGSPGLPGFLGPRGPPGEPGEK 1374
                   PG  G  G  G PGP G PG  G     KG +G PG PGF+G RG PG  G  
Sbjct: 976  SAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSS 1035

Query: 1375 GVPGKEGVPGKPGE------PGFKGERGDPGIKGDKGP-------PGGKGQPGDPGIPGH 1421
            G+ G  G+PG+ G       PG  G  G PG+KGD G        PG KGQPG+ G  G 
Sbjct: 1036 GITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1095

Query: 1422 KGHTGLMGPQGLPG---ENGPVGPPGP---PGQPGFPGLRGESPSMETLRRLIQEELGKQ 1475
            KG  GL+G  G PG   E+G VG  G    PG PGFPG+ G           ++ E G  
Sbjct: 1096 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG-----------MRGEPGLP 1144

Query: 1476 LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPI 1535
              +     +  +    +   +G PG PG  G +GLPG  G  G PG P   G+ GP+G  
Sbjct: 1145 GSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPG-PSITGVPGPAGLP 1203

Query: 1536 GPKGERGAKG----DPGAPGV-------GLRGEMGPPGIPGQPG---------EPGYAKD 1575
            GPKGE+G  G     PG PG+       G  G  GP G+PG PG         +PG    
Sbjct: 1204 GPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPG--DP 1261

Query: 1576 GLPGIPGPQGETGPAGHPGLPGP------------PGPPGQCDPSQCAYFASLAARPGNV 1623
            G PG+ G +G  GPAG PG PGP            PG PG   P         +  PG +
Sbjct: 1262 GRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGEL 1321



 Score =  620 bits (1599), Expect = e-177
 Identities = 418/1037 (40%), Positives = 489/1037 (47%), Gaps = 201/1037 (19%)

Query: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511
            P   PP  P  PG   +  L         G KG  G  G  G  GP G  G +GP+G  G
Sbjct: 489  PNTGPPGEPGPPGPWGLIGLP--------GLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 540

Query: 512  PKGEKGDVGIG-----PFGQGEKGEKGSLGLPGPPGRDGSKGM-----------RGEPGE 555
            PKG+KG+  +      P  +G+ G +G  G+ G PG+DG  G+           +G PGE
Sbjct: 541  PKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGE 600

Query: 556  LGEPGLPGEVGMRGPQG-----------PPGLPGPPGRVGAPGLQGERGEKGTR------ 598
             G PGLPGE G  GP G           P GLPG  G+ G PG QG  G KG        
Sbjct: 601  KGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIP 660

Query: 599  ---------------GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP 643
                           G KG RGL G PG+PG +G +G PG  G+       G  GP G  
Sbjct: 661  GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEK 720

Query: 644  GVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI--GPEGRDGPPGLQGLRGKKGDM 701
            G+PG      GL G+ G PG  G  G PG  GA G I     G  G  GLQGL G KG +
Sbjct: 721  GLPGF----PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFL 776

Query: 702  GPPGIPGLLG------LQGPPGPPGVPGPPGPGGSPGLPG---------EIGFPGKPGPP 746
            G  G+PGL G      L GP G  G PG PG  G PG PG         + G PG PG P
Sbjct: 777  GDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFP 836

Query: 747  GPTGPPGKDGPNGPPGPPGT---KGEPGERGEDGLPGKPGLRGEIGEQGLAGRP------ 797
            G +G PGK G  G  GPPG+   KG PG +G  G PG  GL+G  G  G+AG P      
Sbjct: 837  GISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPK 896

Query: 798  GEKGEAG------LPGAPGFPGVRG---------------------EKGDQGEKGELGLP 830
            GEKG  G      +PG PG PG RG                     EKGD+G  G +G+P
Sbjct: 897  GEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIP 956

Query: 831  G---------LKGD---------------RGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE 866
                      LKGD               RG+KGEAG  GPPGLPG        P +PG 
Sbjct: 957  SPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGA-------PGLPGI 1009

Query: 867  QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926
               KG  G PG PG  G++G PG  G  G TG PG  G+ G+ G  G+ G PGA G  G 
Sbjct: 1010 I--KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGL 1067

Query: 927  PGPSG----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976
             G +G          P G  G  G +GT G+DG  G  G  G +G  G VG  GD G PG
Sbjct: 1068 KGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPG 1127

Query: 977  LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA--LGGQCVKGDRGAPGIPG 1034
             PG PG       G+RG PGLPG  G + A G + GS       G     G  G  G+PG
Sbjct: 1128 APGFPGVA-----GMRGEPGLPGSSGHQGAIGPL-GSPGLIGPKGFPGFPGLHGLNGLPG 1181

Query: 1035 SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL----PGFPGPQGPAGRDGAPGNPGERG 1090
            + G+ G PG  + G PGP+G PG KG  G  G+    PG PG +G  G  G PG  G  G
Sbjct: 1182 TKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAG 1241

Query: 1091 PPGKPGLS--SLLS--PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
             PG PG+S  SL++  PGD             PG PGL G  G  G  G PG PG    +
Sbjct: 1242 LPGAPGISLPSLIAGQPGD-------------PGRPGLDGERGRPGPAGPPGPPGPSSNQ 1288

Query: 1147 GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG---VPGFMGPPGNPGPP 1203
            G  G+ G PG+PGP G  G QG  G  G  GE+G KG +G PG    PG +GPPG+PG P
Sbjct: 1289 GDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFP 1348

Query: 1204 GADGIAGAAGPPGIQGSPGK-------EGPPGPQGPSGLPGIPG------EEGKEGRDGK 1250
            G  G AG  G  G+QG PG+       + PPGP G  G+ GIPG       +G  G  G 
Sbjct: 1349 GMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGS 1408

Query: 1251 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310
             G PG PGK G  GLPGP GA G PG  G  G  G  G  G+ G  G+PG  G   + G 
Sbjct: 1409 KGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGY 1468

Query: 1311 TGPTGPQGPQGPRGPPG 1327
            T     Q  Q P  P G
Sbjct: 1469 TLVKHSQSEQVPPCPIG 1485



 Score =  463 bits (1192), Expect = e-130
 Identities = 335/883 (37%), Positives = 388/883 (43%), Gaps = 201/883 (22%)

Query: 914  AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973
            AAG        G    SG        G RG PG  G +G  G  G  GS G  G +G+ G
Sbjct: 21   AAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERG 80

Query: 974  APGLPGPPG----KGKDGEP------GLRGSPGLPGPLGTKA--ACGKVRGSENCALGGQ 1021
             PGL GP G    KG  G P      G+ G PG PGP G      C   +G+     G  
Sbjct: 81   FPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFP-GPD 139

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI------GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075
               G  G PG+PG  GS+GDP +      G+ G PG  G  G  G  G+ G PG  GP G
Sbjct: 140  GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 199

Query: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP------------- 1122
            P G  G PG PG  GP G  GL      G    +  DV    P GPP             
Sbjct: 200  PPGLQGPPGPPGPLGPDGNMGLGFQGEKG----VKGDVGLPGPAGPPPSTGELEFMGFPK 255

Query: 1123 ------GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176
                  G PG  GF G  G PG PG  GT G+KGE G  G+PG PG  GP GS+G +G  
Sbjct: 256  GKKGSKGEPGPKGFPGISGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP 314

Query: 1177 GEVGQKGDQGHPGVPGFM--------------------------GPPGNPGPPGA----- 1205
            G+ G+KG  G PG+ GF                           G PG+PG PG      
Sbjct: 315  GQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 374

Query: 1206 -DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK-----------EGRDGKPGP 1253
             +GI G  GP G+ G P   G PG  GP G PG+ G++G             GRDG PGP
Sbjct: 375  DEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGP 434

Query: 1254 PGEPG--------------KAGEPGLPGPEGARGPPGFKGHTGDS--------------- 1284
            PG PG              ++G PGL G +G +G  G KG  GDS               
Sbjct: 435  PGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPP 494

Query: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ------GPQGPRGPPGKNGSP------ 1332
            G PGP G  G +GLPG +G  G  G  G  GP       GP GP GP GK G P      
Sbjct: 495  GEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQ 554

Query: 1333 GSPGEPGPSGTPGQK---GSKGENGSPGLP-----------GFLGPRGPPGEPGEKGVPG 1378
            G PG+ G SG+ G +   G  G++G PGLP           GF G +G PG PGEKG PG
Sbjct: 555  GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPG 614

Query: 1379 KEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG------IPGHKGHTGLMGPQG 1432
              G+PG  G PG  G RG PG KG  G PG +G PG  G      IPG  G +G  G  G
Sbjct: 615  PPGLPGN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPG 673

Query: 1433 LPGENGPVGPPGPPGQPGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490
             PG  G  G PG PGQPG  G +GE  SP +  L  L                     P 
Sbjct: 674  FPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPEL---------------------PG 712

Query: 1491 Y--MKSSQGRPGPPGPPGKDGLPGRAGPMGEP--------------GRPGQGGLEGPSGP 1534
            +   +  +G PG PG PGKDGLPG  G  G P              G PG+ GL+G +G 
Sbjct: 713  FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGH 772

Query: 1535 ---IGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPG----------YAKDGLPGI 1580
               +G  G  G KG  G PG +G +GE G PG PGQ G+PG            K GLPG 
Sbjct: 773  KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 832

Query: 1581 PGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623
            PG  G +G  G  G  G  GPPG            L   PG V
Sbjct: 833  PGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLV 875



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 30/77 (38%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 1550 PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609
            P  G RG  GP GI G  G  G+   G  G+ G +GE G    PGL GP GP G   P  
Sbjct: 44   PEKGARGRPGPIGIQGPTGPQGFT--GSTGLSGLKGERG---FPGLLGPYGPKGDKGPMG 98

Query: 1610 CAYFASLAARPGNVKGP 1626
               F  +   PG+   P
Sbjct: 99   VPGFLGINGIPGHPGQP 115


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score =  820 bits (2119), Expect = 0.0
 Identities = 572/1395 (41%), Positives = 666/1395 (47%), Gaps = 291/1395 (20%)

Query: 479  PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLP 538
            P G+KG MGV G +G+ G  G  G  GP G PG  G  G  G      G  G  G  GL 
Sbjct: 89   PKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQG----AVGFPGPDGYPGLL 144

Query: 539  GPPGRDGSKGMRGEP--------GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQG 590
            GPPG  G KG +G+P        G  G+PGLPG  G+ GPQG PG PG  G  G PGLQG
Sbjct: 145  GPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQG 204

Query: 591  ERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA-------------GPQGEKGDV 637
              G  G  G  G  GL GF G+ G  G  G PGP+G               G +G KG+ 
Sbjct: 205  PPGPPGPLGPDGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEP 263

Query: 638  GP------AGPPGVPG-SVVQQEGLKGEQGAPG------PRGHQGAPGPPGARGPIGPEG 684
            GP      +GPPG PG     ++G KGE+G PG      P G +G  GPPG +G  G  G
Sbjct: 264  GPKGFPGISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLG 323

Query: 685  RDGPPGLQGLRGKKGDMG--------------------PPGIPGLLGL------QGPPGP 718
              G  G QG+ G+KGD+G                     PG+PGL GL      QG  GP
Sbjct: 324  FPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGP 383

Query: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGP---PGPT-----GPPGKDGPNGPPGPPGT---- 766
             GVPG P   G PG  G  GFPG  G    PG T     G PG+DG  GPPGPPG     
Sbjct: 384  SGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPE 443

Query: 767  ----------KGEPGERGEDGLPGKPGLRGEIGEQGLA------------GRPGEKGEAG 804
                       G PG RGE G  G  GL+G  G+ G              G PG  G  G
Sbjct: 444  FETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWG 503

Query: 805  LPGAPGFPGVRGEKGDQGEKGELGLPGL------------------------KGDRGEKG 840
            L G PG  G RG++G  G +G  G PGL                         GDRG+ G
Sbjct: 504  LIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSG 563

Query: 841  ---------EAGPAGPPGLPGTTSLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPG 889
                     E G  G PGLPG        P +PG+  QG  GEKG PGLPGE G  G PG
Sbjct: 564  SQGFRGVIGEPGKDGVPGLPGL-------PGLPGDGGQGFPGEKGLPGLPGEKGHPGPPG 616

Query: 890  ELGP--QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV------GAPGPSGPPGSVGAPG- 940
              G    G  GP G  G +G  G PG  G PG+ G        G+ GPSG PG+ G PG 
Sbjct: 617  LPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGP 676

Query: 941  --LRGTPGKDGERGEKGAAGEEGSPGPV---------GPRGDPGAPGLPGPPGKGKDGEP 989
               RG PG  G+ G  G+ GE GSPG V         GPRG+ G PG PG PGK  DG P
Sbjct: 677  KGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK--DGLP 734

Query: 990  GLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV------------------KGDRGAPG 1031
            G+ GSPGLPG   +K A G + G+EN A G Q +                  KG  G PG
Sbjct: 735  GMIGSPGLPG---SKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPG 791

Query: 1032 IPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGLPGFPG------PQGPAGRDG 1081
            + G  G RG PG    +G  G PG SGP G KG  G  G PGFPG       +G  G+ G
Sbjct: 792  LLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKG 851

Query: 1082 APGN------PGERGPPGKPGLSSLL-SPGDINLLAKDVCNDCP-----------PGPPG 1123
             PG+      PG +G PG PGL  L  SPG   +      +              PG PG
Sbjct: 852  PPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPG 911

Query: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKG---EAGPPGLPGPPGIAGPQ------------G 1168
            LPG+PG +G KG+PG  G+ G  G+ G   E G  G PGP GI  P+            G
Sbjct: 912  LPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKG 971

Query: 1169 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA-DGIAGAAGPPGIQGSPGKEGPP 1227
            SQG  G++G  G +GD+G  G PG  G PG PG PG   G++G  GPPG  G  G  G  
Sbjct: 972  SQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLK 1031

Query: 1228 GPQGPSGLPGIPGEEGKEGRDGKPGPPGE---PGKAGE-------PGLPGPEGARGPPGF 1277
            G  G +G PG+PGE G +G  G PG PG    PG  G+        G PGP+G  G  GF
Sbjct: 1032 GSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGF 1091

Query: 1278 KGHTGDSGA------PGPRGESGAMGLPGQEGLPG------------KDGDTGPTGPQGP 1319
            KG  G  G       PG +GE G +G+ G  GLPG            + G  G +G QG 
Sbjct: 1092 KGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGA 1151

Query: 1320 QGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGEPGEKGVP 1377
             GP G PG  G  G PG PG  G  G  G+KG +G+PG  + G  GP G PG  GEKG P
Sbjct: 1152 IGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYP 1211

Query: 1378 GKE-GVPGKPGEPGFKGERGDPGIKGDKGPPGGKG---------QPGDPGIPGHKGHTGL 1427
            G   G PGKPG  G KG+RG PG++G  G PG  G         QPGDPG PG  G  G 
Sbjct: 1212 GIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGR 1271

Query: 1428 MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 1487
             GP G PG  GP    G  G PGFPG+ G  P      + I    G   E  L  +  + 
Sbjct: 1272 PGPAGPPGPPGPSSNQGDTGDPGFPGIPG--PKGPKGDQGIPGFSGLPGELGLKGMRGE- 1328

Query: 1488 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG-------LEGPSGPIGPKGE 1540
             P +M  + G+ GPPG PG  G+ G+AGP G  G  G  G       ++ P GP+G  G 
Sbjct: 1329 -PGFM-GTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGI 1386

Query: 1541 RGAKG---DPGAPG-VGLRGEMGPPGIPGQ------PGEPGYAKD-GLPGIPGPQGETGP 1589
             G  G   DPGA G VGL+G  G PGIPG+      PG PG   D GLPG+ GP G  G 
Sbjct: 1387 DGIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGA 1446

Query: 1590 AGHPGLPGPPGPPGQ 1604
             G  G  G PG PGQ
Sbjct: 1447 PGQQGPFGMPGMPGQ 1461



 Score =  820 bits (2118), Expect = 0.0
 Identities = 582/1444 (40%), Positives = 684/1444 (47%), Gaps = 303/1444 (20%)

Query: 440  SGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG 499
            SG CQ          P P     P   Q GF  +   S   GE+G  G+ GP G  G KG
Sbjct: 36   SGSCQCFPEKGARGRPGPIGIQGPTGPQ-GFTGSTGLSGLKGERGFPGLLGPYGPKGDKG 94

Query: 500  DIGAIGPVGAPGPKGEKGDVG-IGPFG-QGEKGEKGSLGLP---------GPPGRDGSKG 548
             +G  G +G  G  G  G  G  GP G  G  G +G++G P         GPPG  G KG
Sbjct: 95   PMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKG 154

Query: 549  MRGEP--------GELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGE 600
             +G+P        G  G+PGLPG  G+ GPQG PG PG  G  G PGLQG  G  G  G 
Sbjct: 155  SKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGP 214

Query: 601  KGERGLDGFPGKPGDTGQQGRPGPSG-------------VAGPQGEKGDVGP------AG 641
             G  GL GF G+ G  G  G PGP+G               G +G KG+ GP      +G
Sbjct: 215  DGNMGL-GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISG 273

Query: 642  PPGVPG-SVVQQEGLKGEQGAP------GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGL 694
            PPG PG     ++G KGE+G P      GP G +G  GPPG +G  G  G  G  G QG+
Sbjct: 274  PPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGI 333

Query: 695  RGKKGDM--------------------GPPGIPGLLGL------QGPPGPPGVPGPP--- 725
             G+KGD+                    G PG+PGL GL      QG  GP GVPG P   
Sbjct: 334  EGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 393

Query: 726  ------GPGGSPGLPGEIGFPGK--------------PGPPGPTGPP------------- 752
                  GP G PGL G+ G PG+              PGPPGP GPP             
Sbjct: 394  GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE 453

Query: 753  -------GKDGPNGPPGPPGTKGEPG---------ERGEDGLPGKPGLRGEIGEQGLAGR 796
                   G+ GP G  G  G KG+ G           G  G PG PG  G IG  GL G 
Sbjct: 454  SGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 513

Query: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLP------GLKGDRGEK---------GE 841
             G++G  G  G  G PG+ G  G  G KG+ G P      G+ GDRG+          GE
Sbjct: 514  RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGE 573

Query: 842  AGPAGPPGLPGTTSLFTPHPRMPGE--QGPKGEKGDPGLPGEPGLQGRPG--ELGPQGPT 897
             G  G PGLPG        P +PG+  QG  GEKG PGLPGE G  G PG    G  G  
Sbjct: 574  PGKDGVPGLPGL-------PGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLP 626

Query: 898  GPPGAKGQEGAHGAPGAAGNPGAPGHV------GAPGPSGPPGSVGAP---GLRGTPGKD 948
            GP G  G +G  G PG  G PG+ G        G+ GPSG PG+ G P   G RG PG  
Sbjct: 627  GPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTP 686

Query: 949  GERGEKGAAGEEGSPGPV---------GPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPG 999
            G+ G  G+ GE GSPG V         GPRG+ G PG PG P  GKDG PG+ GSPGLP 
Sbjct: 687  GQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP--GKDGLPGMIGSPGLP- 743

Query: 1000 PLGTKAACGKVRGSENCALGGQ------------------CVKGDRGAPGIPGSPGSRGD 1041
              G+K A G + G+EN A G Q                   +KG  G PG+ G  G RG 
Sbjct: 744  --GSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGS 801

Query: 1042 PG----IGVAGPPGPSGPPGDKGSPGSRGLPGF------PGPQGPAGRDGAPGN------ 1085
            PG    +G  G PG SGP G KG  G  G PGF      PG +G  G+ G PG+      
Sbjct: 802  PGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGL 861

Query: 1086 PGERGPPGKPGLSSLL-SPGDINLLAKDVCNDCP-----------PGPPGLPGLPGFKGD 1133
            PG +G PG PGL  L  SPG   +      +              PG PGLPG+PG +G 
Sbjct: 862  PGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGL 921

Query: 1134 KGVPGKPGREGTEGK---KGEAGPPGLPGPPGIAGP------------QGSQGERGADGE 1178
            KG+PG  G+ G  G+    GE G  G PGP GI  P            +GSQG  G++G 
Sbjct: 922  KGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGF 981

Query: 1179 VGQKGDQGHPGVPGFMGPPGNPGPPG-ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237
             G +GD+G  G PG  G PG PG PG   G++G  GPPG  G  G  G  G  G +G PG
Sbjct: 982  PGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPG 1041

Query: 1238 IPGEEGKEGRDGKPGPPGE---PGKAGE-------PGLPGPEGARGPPGFKGH------T 1281
            +PGE G +G  G PG PG    PG  G+        G PGP+G  G  GFKG        
Sbjct: 1042 MPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLI 1101

Query: 1282 GDSGAPGPRGESGAMGLPGQEGLP------------GKDGDTGPTGPQGPQGPRGPPGKN 1329
            G+ G PG +GE G +G+ G  GLP            G+ G  G +G QG  GP G PG  
Sbjct: 1102 GNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLI 1161

Query: 1330 GSPGSPGEPGPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGEPGEKGVPG-KEGVPGKP 1386
            G  G PG PG  G  G  G+KG +G+PG  + G  GP G PG  GEKG PG   G PGKP
Sbjct: 1162 GPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKP 1221

Query: 1387 GEPGFKGERGDPGIKGDKGPPGG---------KGQPGDPGIPGHKGHTGLMGPQGLPGEN 1437
            G  G KG+RG PG++G  G PG           GQPGDPG PG  G  G  GP G PG  
Sbjct: 1222 GLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPP 1281

Query: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497
            GP    G  G PGFPG+ G  P      + I    G   E  L  +  +  P +M  + G
Sbjct: 1282 GPSSNQGDTGDPGFPGIPG--PKGPKGDQGIPGFSGLPGELGLKGMRGE--PGFM-GTPG 1336

Query: 1498 RPGPPGPPGKDGLPGRAGPMGEPGRPGQGG-------LEGPSGPI---GPKGERGAKGDP 1547
            + GPPG PG  G+ G+AGP G  G  G  G       ++ P GP+   G  G  G  GDP
Sbjct: 1337 KVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDP 1396

Query: 1548 GAPG-VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP---GPPG 1603
            GA G VGL+G  G PGIPG        KDG  G+PGP G  G  G PGL GPP   G PG
Sbjct: 1397 GAQGPVGLQGSKGLPGIPG--------KDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPG 1448

Query: 1604 QCDP 1607
            Q  P
Sbjct: 1449 QQGP 1452



 Score =  800 bits (2066), Expect = 0.0
 Identities = 526/1272 (41%), Positives = 618/1272 (48%), Gaps = 200/1272 (15%)

Query: 450  EPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGA 509
            EP P   P     PG   +G           GEKGE G  G  GLPGP+G +G+ G  G 
Sbjct: 262  EPGPKGFPGISGPPGFPGLG---------TTGEKGEKGEKGIPGLPGPRGPMGSEGVQGP 312

Query: 510  PGPKGEKGDVGIGPFG--QGEKGEKGSLGLPGPP---GRDGSKGMRGEPGELGEPGLPGE 564
            PG +G+KG +G       QG +G+KG +GLPGP      DG+  + G PG+ G PGLPG 
Sbjct: 313  PGQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAV-ISGNPGDPGVPGLPGL 371

Query: 565  VG------MRGPQGPPGLP---GPPGRVGA---PGLQGERGEKG--TRGEKGERGLDGFP 610
             G      +RGP G PGLP   G PG +G    PGL+G++G  G  T G  G  G DG P
Sbjct: 372  KGDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLP 431

Query: 611  GKPGDTGQ--------------------QGRPGPSGVAGPQGEKGD------------VG 638
            G PG  G                     +G  GP G  G +G KGD             G
Sbjct: 432  GPPGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTG 491

Query: 639  PAGPPGVPG--SVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG------ 690
            P G PG PG   ++   GLKG +G  G  G QG  G PG  GP+GP G  G  G      
Sbjct: 492  PPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILST 551

Query: 691  LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG-PG-GSPGLPGEIGFPGKPGPPGP 748
            +QG+ G +GD G  G  G++G  G  G PG+PG PG PG G  G PGE G PG PG  G 
Sbjct: 552  IQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGH 611

Query: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK---------------PGLRGEIGEQGL 793
             GPPG  G NG PG PG +G PG++G+DGLPG+               PG  G  G  G 
Sbjct: 612  PGPPGLPG-NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGT 670

Query: 794  AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 853
             G PG KG  GLPG PG PG  G KG+ G  G + LP L G  G +GE G  G PGLPG 
Sbjct: 671  PGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGK 730

Query: 854  TSL--FTPHPRMPGEQGPKGE--KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG----- 904
              L      P +PG +G  G+    + G PGE GLQG  G  G  G +G PG KG     
Sbjct: 731  DGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKP 790

Query: 905  ----QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960
                 +G  G+PG  G  G PG  G+ GP G  G  G PG  G PG  G  G+KG  G++
Sbjct: 791  GLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKK 850

Query: 961  GSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 1016
            G PG +  +G PG  GLPG PG    KG  G PG+ G P L GP G K + G V      
Sbjct: 851  GPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 910

Query: 1017 ALGGQCVKGDRGAPGIPGSPGSRGDPGI-------GVAGPPGPSGPP------------G 1057
             L G  + G RG  GIPGS G  G  G        G  G PGP G P            G
Sbjct: 911  GLPG--IPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKG 968

Query: 1058 DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLS--PGDINLLAKDVCN 1115
            DKGS GS G  GFPGP+G  G  G PG PG  G PG PG+   +S  PG           
Sbjct: 969  DKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPG----------- 1017

Query: 1116 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGE--- 1172
              PPG  G+ GLPG KG  G+ G PG  G  G +G  G PGLPG  G+ G +G  G+   
Sbjct: 1018 --PPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVE 1075

Query: 1173 -------RGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG--- 1222
                   +G  GE G KG +G  G+ G +G PGN G  G  G++G  G PG  G PG   
Sbjct: 1076 ISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG 1135

Query: 1223 KEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG--FKGH 1280
              G PG  G SG  G  G  G  G  G  G PG PG  G  GLPG +G  G PG    G 
Sbjct: 1136 MRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGV 1195

Query: 1281 TGDSGAPGPRGESG----AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336
             G +G PGP+GE G     +G PG+ GL G+ GD G  G QGP G  G PG +      G
Sbjct: 1196 PGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAG 1255

Query: 1337 EPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERG 1396
            +PG    PG+ G  GE G PG      P GPPG PG     G  G PG PG PG KG +G
Sbjct: 1256 QPGD---PGRPGLDGERGRPG------PAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKG 1306

Query: 1397 DPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRG 1456
            D GI G  G PG  G  G  G PG  G  G +GP G PG  G  G  GP G  G  G  G
Sbjct: 1307 DQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPG 1366

Query: 1457 ESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP 1516
            ++P+ E +                     Q+PP  +    G PG  G PG  G PG  GP
Sbjct: 1367 QTPTAEAV---------------------QVPPGPL----GLPGIDGIPGLTGDPGAQGP 1401

Query: 1517 MGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDG 1576
            +G  G  G  G+ G  GP G  G  GA GDPG PG+      GPPG  G PG+ G    G
Sbjct: 1402 VGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGL-----QGPPGFEGAPGQQG--PFG 1454

Query: 1577 LPGIPGPQGETG 1588
            +PG+PG     G
Sbjct: 1455 MPGMPGQSMRVG 1466



 Score =  773 bits (1996), Expect = 0.0
 Identities = 524/1320 (39%), Positives = 612/1320 (46%), Gaps = 266/1320 (20%)

Query: 526  QGEKGEKGSLGLPGPPGRDG---SKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGR 582
            +G +G  G +G+ GP G  G   S G+ G  GE G PGL G  G +G +GP G+PG  G 
Sbjct: 45   KGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGI 104

Query: 583  VGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGP 642
             G PG  G+ G +G  G  G  G  G  G PG  G  G  GP G+ G +G KGD     P
Sbjct: 105  NGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGD-----P 159

Query: 643  PGVPGSVVQQEGLKGEQGAPGP---RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKG 699
               PGS    +G+KG+ G PG     G QGAPG PGA GP GP G  GPPG  G  G  G
Sbjct: 160  VLAPGSF---KGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDG 216

Query: 700  DMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI---GFP-GKPGPPGPTGPPGKD 755
            +MG       LG QG  G  G  G PGP G P   GE+   GFP GK G  G  GP G  
Sbjct: 217  NMG-------LGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFP 269

Query: 756  GPNGPPGPPG--TKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE---KGEAGLPGAPG 810
            G +GPPG PG  T GE GE+GE G+PG PG RG +G +G+ G PG+   KG  G PG  G
Sbjct: 270  GISGPPGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNG 329

Query: 811  FPGVRGEKGD--------------------QGEKGELGLPGLKGDRGEKGEAGPAGPPGL 850
            F G+ G+KGD                     G+ G  GLPGLKGD G +G  GP+G PGL
Sbjct: 330  FQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGL 389

Query: 851  ------------------------PGTTSLFT---------------PHPRMP------- 864
                                    PG T++                 P P  P       
Sbjct: 390  PALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETL 449

Query: 865  -----------GEQGPKGEKGDPGLPGEPGL---------QGRPGELGPQGP---TGPPG 901
                       GEQGPKG  G  G+ G+ G           G PGE GP GP    G PG
Sbjct: 450  HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPG 509

Query: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961
             KG  G  G+ GA G  GAPG VG  GPSGP G  G P L    G  G+RG+ G+ G  G
Sbjct: 510  LKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRG 569

Query: 962  SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021
              G  G  G PG PGLPG PG G  G PG +G PGLPG  G     G          G +
Sbjct: 570  VIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGLPGPR 629

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI-------GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074
             + GD+G  G+PG  G  G  GI       G  GP G  G PG  G  GSRGLPG PG  
Sbjct: 630  GLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQP 689

Query: 1075 GPAGRDGAPGNPG---------------ERGPPGKPGLSSLLSPGDINLLAKDVCNDCPP 1119
            G +G  G PG+PG               E+G PG PGL     PG   L          P
Sbjct: 690  GSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGL-----PGKDGL----------P 734

Query: 1120 GPPGLPGLPGFKG--------DKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 1171
            G  G PGLPG KG        + G PG+ G +G  G KG  G  GLPG  G+ G  G  G
Sbjct: 735  GMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLG 794

Query: 1172 ERGADGEVGQKGDQGHPGVPGFMGP---PGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228
             +G  G  G  G  G PG PG  GP    G  G PGA G  G +G PG +G+ GK+GPPG
Sbjct: 795  PKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPG 854

Query: 1229 PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPG 1288
                 GLPG+ G  G  G  G  G PG PG AG P L GP+G +G  GF G  G  G PG
Sbjct: 855  SIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPG 914

Query: 1289 PRGESGAMGLPG---------QEGLPGKDGDTGPTGPQGPQGPRGP-------------- 1325
              G  G  G+PG         + G PG+ GD G  GP G   PR P              
Sbjct: 915  IPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQG 974

Query: 1326 -------PGKNGSPGSPGEPGPSGTPGQKGS----KGENGSPGLPGFLGPRGPPGEPGEK 1374
                   PG  G  G  G PGP G PG  G     KG +G PG PGF+G RG PG  G  
Sbjct: 975  SAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSS 1034

Query: 1375 GVPGKEGVPGKPGE------PGFKGERGDPGIKGDKGP-------PGGKGQPGDPGIPGH 1421
            G+ G  G+PG+ G       PG  G  G PG+KGD G        PG KGQPG+ G  G 
Sbjct: 1035 GITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGT 1094

Query: 1422 KGHTGLMGPQGLPG---ENGPVGPPGP---PGQPGFPGLRGESPSMETLRRLIQEELGKQ 1475
            KG  GL+G  G PG   E+G VG  G    PG PGFPG+ G           ++ E G  
Sbjct: 1095 KGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAG-----------MRGEPGLP 1143

Query: 1476 LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPI 1535
              +     +  +    +   +G PG PG  G +GLPG  G  G PG P   G+ GP+G  
Sbjct: 1144 GSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPG-PSITGVPGPAGLP 1202

Query: 1536 GPKGERGAKG----DPGAPGV-------GLRGEMGPPGIPGQPG---------EPGYAKD 1575
            GPKGE+G  G     PG PG+       G  G  GP G+PG PG         +PG    
Sbjct: 1203 GPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPG--DP 1260

Query: 1576 GLPGIPGPQGETGPAGHPGLPGP------------PGPPGQCDPSQCAYFASLAARPGNV 1623
            G PG+ G +G  GPAG PG PGP            PG PG   P         +  PG +
Sbjct: 1261 GRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGEL 1320



 Score =  620 bits (1599), Expect = e-177
 Identities = 418/1037 (40%), Positives = 489/1037 (47%), Gaps = 201/1037 (19%)

Query: 452  PPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG 511
            P   PP  P  PG   +  L         G KG  G  G  G  GP G  G +GP+G  G
Sbjct: 488  PNTGPPGEPGPPGPWGLIGLP--------GLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 539

Query: 512  PKGEKGDVGIG-----PFGQGEKGEKGSLGLPGPPGRDGSKGM-----------RGEPGE 555
            PKG+KG+  +      P  +G+ G +G  G+ G PG+DG  G+           +G PGE
Sbjct: 540  PKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGE 599

Query: 556  LGEPGLPGEVGMRGPQG-----------PPGLPGPPGRVGAPGLQGERGEKGTR------ 598
             G PGLPGE G  GP G           P GLPG  G+ G PG QG  G KG        
Sbjct: 600  KGLPGLPGEKGHPGPPGLPGNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIP 659

Query: 599  ---------------GEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP 643
                           G KG RGL G PG+PG +G +G PG  G+       G  GP G  
Sbjct: 660  GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEK 719

Query: 644  GVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI--GPEGRDGPPGLQGLRGKKGDM 701
            G+PG      GL G+ G PG  G  G PG  GA G I     G  G  GLQGL G KG +
Sbjct: 720  GLPGF----PGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFL 775

Query: 702  GPPGIPGLLG------LQGPPGPPGVPGPPGPGGSPGLPG---------EIGFPGKPGPP 746
            G  G+PGL G      L GP G  G PG PG  G PG PG         + G PG PG P
Sbjct: 776  GDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFP 835

Query: 747  GPTGPPGKDGPNGPPGPPGT---KGEPGERGEDGLPGKPGLRGEIGEQGLAGRP------ 797
            G +G PGK G  G  GPPG+   KG PG +G  G PG  GL+G  G  G+AG P      
Sbjct: 836  GISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPK 895

Query: 798  GEKGEAG------LPGAPGFPGVRG---------------------EKGDQGEKGELGLP 830
            GEKG  G      +PG PG PG RG                     EKGD+G  G +G+P
Sbjct: 896  GEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIP 955

Query: 831  G---------LKGD---------------RGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE 866
                      LKGD               RG+KGEAG  GPPGLPG        P +PG 
Sbjct: 956  SPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGA-------PGLPGI 1008

Query: 867  QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 926
               KG  G PG PG  G++G PG  G  G TG PG  G+ G+ G  G+ G PGA G  G 
Sbjct: 1009 I--KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGL 1066

Query: 927  PGPSG----------PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976
             G +G          P G  G  G +GT G+DG  G  G  G +G  G VG  GD G PG
Sbjct: 1067 KGDNGQTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPG 1126

Query: 977  LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCA--LGGQCVKGDRGAPGIPG 1034
             PG PG       G+RG PGLPG  G + A G + GS       G     G  G  G+PG
Sbjct: 1127 APGFPGVA-----GMRGEPGLPGSSGHQGAIGPL-GSPGLIGPKGFPGFPGLHGLNGLPG 1180

Query: 1035 SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL----PGFPGPQGPAGRDGAPGNPGERG 1090
            + G+ G PG  + G PGP+G PG KG  G  G+    PG PG +G  G  G PG  G  G
Sbjct: 1181 TKGTHGTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAG 1240

Query: 1091 PPGKPGLS--SLLS--PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 1146
             PG PG+S  SL++  PGD             PG PGL G  G  G  G PG PG    +
Sbjct: 1241 LPGAPGISLPSLIAGQPGD-------------PGRPGLDGERGRPGPAGPPGPPGPSSNQ 1287

Query: 1147 GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG---VPGFMGPPGNPGPP 1203
            G  G+ G PG+PGP G  G QG  G  G  GE+G KG +G PG    PG +GPPG+PG P
Sbjct: 1288 GDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFP 1347

Query: 1204 GADGIAGAAGPPGIQGSPGK-------EGPPGPQGPSGLPGIPG------EEGKEGRDGK 1250
            G  G AG  G  G+QG PG+       + PPGP G  G+ GIPG       +G  G  G 
Sbjct: 1348 GMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGS 1407

Query: 1251 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310
             G PG PGK G  GLPGP GA G PG  G  G  G  G  G+ G  G+PG  G   + G 
Sbjct: 1408 KGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMPGMPGQSMRVGY 1467

Query: 1311 TGPTGPQGPQGPRGPPG 1327
            T     Q  Q P  P G
Sbjct: 1468 TLVKHSQSEQVPPCPIG 1484



 Score =  463 bits (1192), Expect = e-130
 Identities = 335/883 (37%), Positives = 388/883 (43%), Gaps = 201/883 (22%)

Query: 914  AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973
            AAG        G    SG        G RG PG  G +G  G  G  GS G  G +G+ G
Sbjct: 20   AAGEKSYGKPCGGQDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERG 79

Query: 974  APGLPGPPG----KGKDGEP------GLRGSPGLPGPLGTKA--ACGKVRGSENCALGGQ 1021
             PGL GP G    KG  G P      G+ G PG PGP G      C   +G+     G  
Sbjct: 80   FPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQPGPRGPPGLDGCNGTQGAVGFP-GPD 138

Query: 1022 CVKGDRGAPGIPGSPGSRGDPGI------GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075
               G  G PG+PG  GS+GDP +      G+ G PG  G  G  G  G+ G PG  GP G
Sbjct: 139  GYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAG 198

Query: 1076 PAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP------------- 1122
            P G  G PG PG  GP G  GL      G    +  DV    P GPP             
Sbjct: 199  PPGLQGPPGPPGPLGPDGNMGLGFQGEKG----VKGDVGLPGPAGPPPSTGELEFMGFPK 254

Query: 1123 ------GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 1176
                  G PG  GF G  G PG PG  GT G+KGE G  G+PG PG  GP GS+G +G  
Sbjct: 255  GKKGSKGEPGPKGFPGISGPPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP 313

Query: 1177 GEVGQKGDQGHPGVPGFM--------------------------GPPGNPGPPGA----- 1205
            G+ G+KG  G PG+ GF                           G PG+PG PG      
Sbjct: 314  GQQGKKGTLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 373

Query: 1206 -DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK-----------EGRDGKPGP 1253
             +GI G  GP G+ G P   G PG  GP G PG+ G++G             GRDG PGP
Sbjct: 374  DEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGP 433

Query: 1254 PGEPG--------------KAGEPGLPGPEGARGPPGFKGHTGDS--------------- 1284
            PG PG              ++G PGL G +G +G  G KG  GDS               
Sbjct: 434  PGPPGPPSPEFETETLHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPP 493

Query: 1285 GAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ------GPQGPRGPPGKNGSP------ 1332
            G PGP G  G +GLPG +G  G  G  G  GP       GP GP GP GK G P      
Sbjct: 494  GEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQ 553

Query: 1333 GSPGEPGPSGTPGQK---GSKGENGSPGLP-----------GFLGPRGPPGEPGEKGVPG 1378
            G PG+ G SG+ G +   G  G++G PGLP           GF G +G PG PGEKG PG
Sbjct: 554  GMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPG 613

Query: 1379 KEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG------IPGHKGHTGLMGPQG 1432
              G+PG  G PG  G RG PG KG  G PG +G PG  G      IPG  G +G  G  G
Sbjct: 614  PPGLPGN-GLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPG 672

Query: 1433 LPGENGPVGPPGPPGQPGFPGLRGE--SPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490
             PG  G  G PG PGQPG  G +GE  SP +  L  L                     P 
Sbjct: 673  FPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPEL---------------------PG 711

Query: 1491 Y--MKSSQGRPGPPGPPGKDGLPGRAGPMGEP--------------GRPGQGGLEGPSGP 1534
            +   +  +G PG PG PGKDGLPG  G  G P              G PG+ GL+G +G 
Sbjct: 712  FPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFGAENGAPGEQGLQGLTGH 771

Query: 1535 ---IGPKGERGAKGDPGAPG-VGLRGEMGPPGIPGQPGEPG----------YAKDGLPGI 1580
               +G  G  G KG  G PG +G +GE G PG PGQ G+PG            K GLPG 
Sbjct: 772  KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 831

Query: 1581 PGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNV 1623
            PG  G +G  G  G  G  GPPG            L   PG V
Sbjct: 832  PGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLV 874



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 30/77 (38%), Positives = 35/77 (45%), Gaps = 5/77 (6%)

Query: 1550 PGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQ 1609
            P  G RG  GP GI G  G  G+   G  G+ G +GE G    PGL GP GP G   P  
Sbjct: 43   PEKGARGRPGPIGIQGPTGPQGFT--GSTGLSGLKGERG---FPGLLGPYGPKGDKGPMG 97

Query: 1610 CAYFASLAARPGNVKGP 1626
               F  +   PG+   P
Sbjct: 98   VPGFLGINGIPGHPGQP 114


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  786 bits (2029), Expect = 0.0
 Identities = 471/1054 (44%), Positives = 539/1054 (51%), Gaps = 96/1054 (9%)

Query: 453  PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGP 512
            P  PP     PG +  GF        PAGE GE G  GP G  GP G  G  G  G PG 
Sbjct: 98   PRGPPGAAGAPGPQ--GF------QGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGK 149

Query: 513  KGEKGDVGI-GPFGQGEKGEKGSLGLPG------PPGRDGSKGMRGEPGELGEPGLPGEV 565
             G  G+ G+ GP  QG +G  G+ GLPG        G DG KG  G PG  GEPG PGE 
Sbjct: 150  PGRPGERGVVGP--QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGEN 207

Query: 566  GMRGPQGPPGLPGPPGRVGAPGLQGERGEKGT------RGEKGERGLDGFPGKPGDTGQQ 619
            G  G  G  GLPG  GRVGAPG  G RG  G+       G  G  G  GFPG PG  G+ 
Sbjct: 208  GTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEI 267

Query: 620  GRPGPSGVAGPQGEKGDVG------PAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGP 673
            G  G +G AGP G +G+VG      P GPPG PG+     GL G +GA G  G  GAPG 
Sbjct: 268  GAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGA----NGLTGAKGAAGLPGVAGAPGL 323

Query: 674  PGARGPIGPEGRDGPPGLQGL------RGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727
            PG RG  GP G  G  G +GL       G KG+ G  G PG  G QGPPGP G  G  GP
Sbjct: 324  PGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGP 383

Query: 728  GGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE---RGEDGLPGKPGL 784
             G  G  G  G PG  G PG  G PG DG  G  GPPG++G  G    RG +G  G+PG 
Sbjct: 384  NGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGE 443

Query: 785  RGEIGEQGLAGRPG------EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838
             G +G +GL G PG      ++G  GLPG  G PG  G  G +GE G +G PG KG  G+
Sbjct: 444  PGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGD 503

Query: 839  KGEAGPAGPPGLPGTTSLFTPHPRM-----PGEQGPKGEKGDPGLPGEPGLQGRPGELGP 893
             G+ G  G  GL G      P         PG QG +G KG+ G PG PG QG PG  GP
Sbjct: 504  PGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGP 563

Query: 894  QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGE 953
             G  G PG +G  G  G PG AG  G  G  G  G +GP G +G+ G  G PG DG +GE
Sbjct: 564  AGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGE 623

Query: 954  KGAAGEEGSPGPVGPRGDPGAPGLPG-PPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRG 1012
             G  G  G+ GP GP G PG  G  G P GKG+ GEPGLRG  G PG  G + A G V  
Sbjct: 624  PGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAV-- 681

Query: 1013 SENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFP 1071
                           GAPG  G+ G RG+ G  G AGP GP G PG++G  G  G  GF 
Sbjct: 682  ---------------GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726

Query: 1072 GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFK 1131
            GP G AG+ GA G  G +GP G+ G+     P         V    P GP G PG  G +
Sbjct: 727  GPAGAAGQPGAKGERGAKGPKGENGVVGPTGP---------VGAAGPAGPNGPPGPAGSR 777

Query: 1132 GDKGVPGKPGREGTEGKKGEAGPPGL---PGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188
            GD G PG  G  G  G+ G  GP G+   PGPPG AG +G +G RG  G VG+ G+ G  
Sbjct: 778  GDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAV 837

Query: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248
            G PGF G  G  G  G  G  G  GP G+ G+PG  G PG +G  GLPG+ G  G+ G  
Sbjct: 838  GPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPL 897

Query: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308
            G  GPPG  G  G  G PG  GA   PG  G  G+ G  GP G  G  G  G+ G PG  
Sbjct: 898  GIAGPPGARGPPGAVGSPGVNGA---PGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNI 954

Query: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368
            G  G  G  GP GP GP GK+G+ G   E GPSG  G  G+ G  G  G  G  G +G P
Sbjct: 955  GPVGAAGAPGPHGPVGPAGKHGNRG---ETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011

Query: 1369 GEPGEKGVPGKEGVPGKPGEPGFKGERGD---PGIKGDKGPPGGKGQPGDPGIPGHKGHT 1425
            GE G +G+PG +G  G  G PG  G  GD   PG  G  GP G  G  G  G  G  GH 
Sbjct: 1012 GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHP 1071

Query: 1426 GLMGPQGL---PGENGPVGPPGPPGQPGFPGLRG 1456
            G +GP G+    G  GP GPPGPPG PG PG+ G
Sbjct: 1072 GTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score =  779 bits (2012), Expect = 0.0
 Identities = 481/1116 (43%), Positives = 541/1116 (48%), Gaps = 121/1116 (10%)

Query: 563  GEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERG--LDGFPGK-----PGD 615
            G  G RGP+G  G PGPPGR G  G  G  G  G  G  G  G     + GK     PG 
Sbjct: 33   GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92

Query: 616  TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRG---HQGAPG 672
             G  G  GP G AG  G +G  GPAG PG PG      G +G  G PG  G   H G PG
Sbjct: 93   MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQT-GPAGARGPAGPPGKAGEDGHPGKPG 151

Query: 673  PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732
             PG RG +GP+G  G PG  GL G KG  G  G+ GL G  G PG  G PG PG  G+PG
Sbjct: 152  RPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211

Query: 733  LPGEIGFPG---KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIG 789
              G  G PG   + G PGP G  G DG  GP GP G  G  G  G  G PG  G  G +G
Sbjct: 212  QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271

Query: 790  EQGLAGRPGEKGEAGLPGAPGF---PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 846
              G AG  G +GE GLPG  G    PG  G  G  G KG  GLPG+ G  G  G  G  G
Sbjct: 272  NAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG 331

Query: 847  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906
            P G  G T          G +G  GE G  G  GE G +G PG  GPQGP GP G +G+ 
Sbjct: 332  PVGAAGAT----------GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKR 381

Query: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGS------VGAPGLRGTPGKDGERGEKGAAGEE 960
            G +G  G+AG PG PG  G+PG  G PG+      +G PG RG  G  G RG  G AG  
Sbjct: 382  GPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRP 441

Query: 961  GSPGPVGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKV-----RG-- 1012
            G PG +GPRG PG+PG  GP GK G  G PG+ G PG  GP G +   G +     +G  
Sbjct: 442  GEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPT 501

Query: 1013 ---SENCALGGQCVKGDRGAPGIPGSPGSRGDPGI----------------GVAGPPGPS 1053
                +N   G   + G RGAPG  G+ G++G PG                 G  G PGPS
Sbjct: 502  GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPS 561

Query: 1054 GPPGDKGSPGSRGLPG---FPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSP------- 1103
            GP G+ G PG RGL G    PGP GP G  G PG  G  GP G  G      P       
Sbjct: 562  GPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK 621

Query: 1104 GDINLLAKDVCNDCPPGPPGLPG------LPGFKGDKGVPGKPGREGTEGKKGEAGPPGL 1157
            G+  ++   V    P GP GLPG      +PG KG+KG PG  G  G  G+ G  G PG 
Sbjct: 622  GEPGVVGA-VGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGA 680

Query: 1158 PGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPG---------FMGPPGNPGPPGADGI 1208
             G PG AG  G +GE GA G  G  G +G PG  G         F GP G  G PGA G 
Sbjct: 681  VGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE 740

Query: 1209 AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 1268
             GA GP G  G  G  GP G  GP+G  G PG  G  G  G PG  G PG AG  G PGP
Sbjct: 741  RGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGP 800

Query: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK 1328
             G  GPPG  G  G  G  GPRG+ G +G  G+ G  G  G  G  GP G  G  GPPG 
Sbjct: 801  SGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGT 860

Query: 1329 NGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388
             G  G  G PG  G PG +G +G  G  G  G  GP G  G PG +G PG  G PG  G 
Sbjct: 861  PGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGA 920

Query: 1389 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448
            PG  G  G+PG   + GPPG  GQPG  G  G+ G+ G +G  G PG +GPVGP G  G 
Sbjct: 921  PGEAGRDGNPG---NDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGN 977

Query: 1449 PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKD 1508
             G  G  G                              + PA     +G  GP G  G  
Sbjct: 978  RGETGPSGP-----------------------------VGPAGAVGPRGPSGPQGIRGDK 1008

Query: 1509 GLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQP 1567
            G PG  GP G PG  G  GL+G  G  G  G++GA G  G  G  G  G  GP G  G+ 
Sbjct: 1009 GEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRT 1068

Query: 1568 GEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPG 1603
            G PG    G  GI GPQG  GPAG PG PGPPGPPG
Sbjct: 1069 GHPGTV--GPAGIRGPQGHQGPAGPPGPPGPPGPPG 1102



 Score =  755 bits (1950), Expect = 0.0
 Identities = 463/1101 (42%), Positives = 524/1101 (47%), Gaps = 140/1101 (12%)

Query: 527  GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLP----------------------GE 564
            G++G +G  G PGPPGRDG  G  G PG    PG P                      G 
Sbjct: 36   GDRGPRGERGPPGPPGRDGEDGPTGPPGP---PGPPGPPGLGGNFAAQYDGKGVGLGPGP 92

Query: 565  VGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGD---TGQQGR 621
            +G+ GP+GPPG  G PG  G  G  GE GE G  G  G RG  G PGK G+    G+ GR
Sbjct: 93   MGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR 152

Query: 622  PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQ--EGLKGEQGAPGPRGHQGA------PGP 673
            PG  GV GPQG +G  G  G PG  G       +GLKG+ GAPG +G  GA      PG 
Sbjct: 153  PGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQ 212

Query: 674  PGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP--------- 724
             GARG  G  GR G PG  G RG  G +GP G  G +G  GPPG PG PGP         
Sbjct: 213  TGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGN 272

Query: 725  PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKD---GPNGPPGPPGTKGEPGERGEDGLPGK 781
             GP G  G  GE+G PG  GP GP G PG +   G  G  G PG  G PG  G  G+PG 
Sbjct: 273  AGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGP 332

Query: 782  PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841
             G  G  G +GL G PG  G  G  G  G PG  G +G  G  GE    G +G  GE G 
Sbjct: 333  VGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGE---EGKRGPNGEAGS 389

Query: 842  AGPAGPPGL---PGTTSL--------FTPHPRMPGEQGP---KGEKGDPGLPGEPGLQ-- 885
            AGP GPPGL   PG+  L            P   G  GP   +G  GD G PGEPGL   
Sbjct: 390  AGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP 449

Query: 886  ----GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS------ 935
                G PG +GP G  GP G  G +G  G  G AG  G PG++G PGP GP G       
Sbjct: 450  RGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGD 509

Query: 936  ---VGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP---GLPGPPGK----GK 985
                G  G RG PG DG  G +G  G +G  G  G +G PG P   GLPGP G     GK
Sbjct: 510  KGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGK 569

Query: 986  DGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-I 1044
             GE GL G  GLPGP G +   G     E+ A G     G RG  G PG  G++G+PG +
Sbjct: 570  PGERGLHGEFGLPGPAGPRGERGP--PGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627

Query: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104
            G  G  GPSGP G  G  G+ G+PG  G +G  G  G  GNPG  G  G PG      P 
Sbjct: 628  GAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687

Query: 1105 DINLLAKDVCNDCPPGPPGLPGLP------------GFKGDKGVPGKPGREGTEGKKGEA 1152
                   +     P GP G  G P            GF G  G  G+PG +G  G KG  
Sbjct: 688  GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPK 747

Query: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212
            G  G+ GP G  G  G  G  G  G  G +GD G PG+ GF G  G  GPPG  GI+G  
Sbjct: 748  GENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPP 807

Query: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272
            GPPG  G  G  GP G QGP G  G  G  G  G  G+ GP GE G AG PG PGP+G  
Sbjct: 808  GPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLL 867

Query: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332
            G PG  G  G  G  G  G +GA+G PG  G+ G  G  GP G  G  G  G PG+ G  
Sbjct: 868  GAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRD 927

Query: 1333 GSPGEPGPSGTPGQKGSKGENGSP---------GLPGFLGPRGPPGEPGEKGVPGKEGVP 1383
            G+PG  GP G  GQ G KGE G P         G PG  GP GP G+ G +G  G  G  
Sbjct: 928  GNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPV 987

Query: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL------MGPQGLPGEN 1437
            G  G  G +G  G  GI+GDKG PG KG  G PG+ GH G  GL       G QG PG  
Sbjct: 988  GPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSV 1047

Query: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497
            GP GP GP G  G  G  G +    T                       + PA ++  QG
Sbjct: 1048 GPAGPRGPAGPSGPAGKDGRTGHPGT-----------------------VGPAGIRGPQG 1084

Query: 1498 RPGPPGPPGKDGLPGRAGPMG 1518
              GP GPPG  G PG  G  G
Sbjct: 1085 HQGPAGPPGPPGPPGPPGVSG 1105



 Score =  748 bits (1932), Expect = 0.0
 Identities = 458/1085 (42%), Positives = 530/1085 (48%), Gaps = 107/1085 (9%)

Query: 592  RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGD-----------VGPA 640
            +G  G RG +GERG  G PG+ G+ G  G PGP G  GP G  G+           +GP 
Sbjct: 32   KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP- 90

Query: 641  GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700
            GP G+ G      G  G  GAPGP+G QG  G PG  G  GP G  GP G  G  G+ G 
Sbjct: 91   GPMGLMGP----RGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGH 146

Query: 701  MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPG---KPGPPGPTGPPGKDGP 757
             G PG PG  G+ GP G  G PG PG  G  G+ G  G  G   +PG PG  G PG  G 
Sbjct: 147  PGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGE 206

Query: 758  NGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGE 817
            NG PG  G +G PGERG  G PG  G RG  G  G  G  G  G AG PG PG PG +GE
Sbjct: 207  NGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGE 266

Query: 818  KGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF----------------TPHP 861
             G  G  G  G  G +G+ G  G +GP GPPG PG   L                  P P
Sbjct: 267  IGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGP 326

Query: 862  R-MPGEQGPKGEKGDPGLPGEPGL---------QGRPGELGPQGPTGPPGAKGQEGAHGA 911
            R +PG  G  G  G  GL GEPG          +G PG  GPQGP GP G +G+ G +G 
Sbjct: 327  RGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGE 386

Query: 912  PGAAGNPGAPGHVGAPGPSGPPGS------VGAPGLRGTPGKDGERGEKGAAGEEGSPGP 965
             G+AG PG PG  G+PG  G PG+      +G PG RG  G  G RG  G AG  G PG 
Sbjct: 387  AGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446

Query: 966  VGPRGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKAACGKVR-GSENCALGGQCV 1023
            +GPRG PG+PG  GP GK G  G PG+ G PG  GP G +   G +         G    
Sbjct: 447  MGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGK 506

Query: 1024 KGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGA 1082
             GD+G  G+ G+ G+ G  G  G  GPPGP G  G KG  G  G PGF G  GP+G  G 
Sbjct: 507  NGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGE 566

Query: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 1142
             G PGERG  G+ GL     P                GPPG  G  G  G  G  G  G 
Sbjct: 567  VGKPGERGLHGEFGLPGPAGPRGER------------GPPGESGAAGPTGPIGSRGPSGP 614

Query: 1143 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGP 1202
             G +G KGE G  G  G  G +GP G  GERGA G  G KG++G PG+ G +G PG  G 
Sbjct: 615  PGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA 674

Query: 1203 PGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE 1262
             GA G  GA GP G  G  G+ G  GP GP+G  G PGE G+ G  G  G  G  G AG+
Sbjct: 675  RGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQ 734

Query: 1263 PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP 1322
            PG  G  GA+GP G  G  G +G  G  G +G  G PG  G  G  G  G TG  G  G 
Sbjct: 735  PGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGR 794

Query: 1323 RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGV 1382
             GPPG +G  G PG PGP+G  G +G +G+ G  G  G +G  GPPG  GEKG  G+ G 
Sbjct: 795  TGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGT 854

Query: 1383 PGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442
             G PG PG +G  G PGI G  G  G +G PG  G  G  G  G+ GP G  G  G VG 
Sbjct: 855  AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGS 914

Query: 1443 PGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPP 1502
            PG  G PG  G  G   +     R  Q                   P + K  +G PG  
Sbjct: 915  PGVNGAPGEAGRDGNPGNDGPPGRDGQ-------------------PGH-KGERGYPGNI 954

Query: 1503 GPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV----GLRGEM 1558
            GP G  G PG  GP+G  G+ G  G  GPSGP+GP G  G +G  G  G+    G  GE 
Sbjct: 955  GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014

Query: 1559 GPPGIPGQPGEPGYAKDGLPGIPG---------------PQGETGPAGHPGLPGPPGPPG 1603
            GP G+PG  G  G    GLPGI G               P+G  GP+G  G  G  G PG
Sbjct: 1015 GPRGLPGLKGHNGL--QGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072

Query: 1604 QCDPS 1608
               P+
Sbjct: 1073 TVGPA 1077



 Score =  691 bits (1782), Expect = 0.0
 Identities = 449/1091 (41%), Positives = 504/1091 (46%), Gaps = 193/1091 (17%)

Query: 692  QGLRGKKGDMGPPGIPGLLGLQGPPGPP---------GVPGPPGPGGSPGL--------- 733
            Q L+ +    GP G  G  G +GPPGPP         G PGPPGP G PGL         
Sbjct: 23   QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYD 82

Query: 734  -------PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786
                   PG +G  G  GPPG  G PG  G  GP G PG  G+ G  G  G  G PG  G
Sbjct: 83   GKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAG 142

Query: 787  EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 846
            E G  G  GRPGE+G  G  GA GFPG  G  G +G +G  GL GLKG  G  G  G  G
Sbjct: 143  EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPG 202

Query: 847  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906
             PG  GT       P   G +G  GE+G  G PG  G +G  G +GP GP GP G+ G  
Sbjct: 203  APGENGT-------PGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255

Query: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR------GTPGKDGERGEKGAA--- 957
            G  GAPG  G  GA G+ G  GP+GP G VG PGL       G PG +G  G KGAA   
Sbjct: 256  GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315

Query: 958  ---------GEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAAC 1007
                     G  G PGPVG  G  GA GL G PG  G  GE G +G PG  GP G     
Sbjct: 316  GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375

Query: 1008 GK--VRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG----IGVAGPP---GPSGPPGD 1058
            G+   RG      G     G  G PG+ GSPGSRG PG     GV GPP   G SGP G 
Sbjct: 376  GEEGKRGPN----GEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431

Query: 1059 KGSPGSRGLPGFPGPQGPAGRDGAPGN---PGERGPPGKPGLSSLLSPGDINLLAKDVCN 1115
            +G  G  G PG PG  GP G  G+PGN    G+ GP G PG+     P        +  N
Sbjct: 432  RGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGN 491

Query: 1116 DCPPGPPGLPGLPGFKGDK------------------GVPGKPGREGTEGKKGEAGPP-- 1155
               PGP G  G PG  GDK                  G  G PG +G +G KGE GPP  
Sbjct: 492  IGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGP 551

Query: 1156 ----GLPGPPGIAGPQGSQGERGADGEV---GQKGDQGHPGVPGFMGPPGNPGPPGADGI 1208
                GLPGP G AG  G  GERG  GE    G  G +G  G PG  G  G  GP G+ G 
Sbjct: 552  PGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGP 611

Query: 1209 AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGP 1268
            +G  GP G +G PG  G  G  GPSG  G+PGE G  G  G  G  GEPG  GE G PG 
Sbjct: 612  SGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGR 671

Query: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGK 1328
            +GARG PG  G  G +GA G RGE+GA G  G  G  G  G+ G  GP GP G  GP G 
Sbjct: 672  DGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGA 731

Query: 1329 NGSPGSPGE------------------------PGPSGTPGQKGSKGENGSPGLPGFLGP 1364
             G PG+ GE                         GP+G PG  GS+G+ G PG+ GF G 
Sbjct: 732  AGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGA 791

Query: 1365 RGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD---------------PGIKGDKGPPGG 1409
             G  G PG  G+ G  G PG  G+ G +G RGD               PG  G+KGP G 
Sbjct: 792  AGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGE 851

Query: 1410 KGQPGDPGIPGHKGHTGL---------MGPQGLPGENGPVGPPGPPGQPGFPGLRGE--- 1457
             G  G PG PG +G  G           G +GLPG  G VG PGP G  G PG RG    
Sbjct: 852  AGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGA 911

Query: 1458 --SPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG 1515
              SP +         E G+                      G PG  GPPG+DG PG  G
Sbjct: 912  VGSPGVNG----APGEAGR---------------------DGNPGNDGPPGRDGQPGHKG 946

Query: 1516 PMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPG 1565
              G PG     G  G  GP GP+GP G+ G +G+ G  G       VG RG  GP GI G
Sbjct: 947  ERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRG 1006

Query: 1566 QPGEPG----------YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFAS 1615
              GEPG             +GL G+PG  G  G  G PG  GP GP G   PS  A    
Sbjct: 1007 DKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDG 1066

Query: 1616 LAARPGNVKGP 1626
                PG V GP
Sbjct: 1067 RTGHPGTV-GP 1076



 Score =  615 bits (1586), Expect = e-175
 Identities = 386/882 (43%), Positives = 439/882 (49%), Gaps = 91/882 (10%)

Query: 439  PSGPCQVTVVTEPPPPPPPQRPP-TPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497
            P+GP         P    P  PP  PG+   G       +   G  G  G+ GP G+PGP
Sbjct: 275  PAGPAGPRGEVGLPGLSGPVGPPGNPGAN--GLTGAKGAAGLPGVAGAPGLPGPRGIPGP 332

Query: 498  KGDIGAIGP---VGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPG 554
             G  GA G    VG PGP G KG+        G KGE GS G  GPPG  G +G RG  G
Sbjct: 333  VGAAGATGARGLVGEPGPAGSKGE-------SGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385

Query: 555  ELGEPGLPGEVGMRGPQGPPGLPG---------PPGRVGAPGLQGERGEKGTRGEKGERG 605
            E G  G PG  G+RG  G  GLPG         PPG  GA G  G RG  G  G  GE G
Sbjct: 386  EAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG 445

Query: 606  L---DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSV--VQQEGLKGEQG 660
            L    G PG PG+ G  G+ GP G+ G  G  G +GPAG  G PG++     +G  G+ G
Sbjct: 446  LMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPG 505

Query: 661  APGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPG 720
              G +GH G  G  GA GP G  G  GPPG QG++G KG+ GPPG PG  GL GP GP G
Sbjct: 506  KNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAG 565

Query: 721  VPGPPGPGGSPG---LPGEIGFPGKPGPPG------PTGPPGKDGPNGPPGPPGTKGEPG 771
              G PG  G  G   LPG  G  G+ GPPG      PTGP G  GP+GPPGP G KGEPG
Sbjct: 566  EVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPG 625

Query: 772  ERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA------PGFPGVRGEKGDQGEKG 825
              G  G  G  G  G  GE+G AG PG KGE G PG       PG  G RG  G  G  G
Sbjct: 626  VVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPG 685

Query: 826  ELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 885
              G  G +G+ G  G AGPAGP G PG      P     G  GP G  G PG  GE G +
Sbjct: 686  PAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGP-AGPNGFAGPAGAAGQPGAKGERGAK 744

Query: 886  GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG---APGHVGAPGPSGPPGSVGAPGLR 942
            G  GE G  GPTGP GA G  G +G PG AG+ G    PG  G PG +G  G  G  G+ 
Sbjct: 745  GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804

Query: 943  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPL 1001
            G PG  G  G++G  G  G  GPVG  G+ GA G PG  G KG  GE G  G PG PGP 
Sbjct: 805  GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQ 864

Query: 1002 GTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKG 1060
            G   A G         LG   + G RG  G+PG  G+ G+PG +G+AGPPG  GPPG  G
Sbjct: 865  GLLGAPG--------ILG---LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVG 913

Query: 1061 SPGSRGLPGF------PGPQGPAGRDGAPGNPGERGPPGKPG-LSSLLSPGDINLLAKDV 1113
            SPG  G PG       PG  GP GRDG PG+ GERG PG  G + +  +PG         
Sbjct: 914  SPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPG--------- 964

Query: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGP---------PGLPGPPGIA 1164
                P GP G  G  G +G+ G  G  G  G  G +G +GP         PG  GP G+ 
Sbjct: 965  ----PHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLP 1020

Query: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224
            G +G  G +G  G  G  GDQG PG  G  GP G  GP G  G  G  G PG  G  G  
Sbjct: 1021 GLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIR 1080

Query: 1225 GPPG---PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 1263
            GP G   P GP G PG PG  G  G     G  G+  +A +P
Sbjct: 1081 GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQP 1122



 Score =  469 bits (1206), Expect = e-131
 Identities = 299/714 (41%), Positives = 341/714 (47%), Gaps = 107/714 (14%)

Query: 480  AGEKGEMGVAGPMGLPGPKGDIGAIG---PVGAPGPKGEKGDVGIGPFGQGEKGEKGSLG 536
            AG  GE G+ GP GLPG  G+IG  G   PVG PG  G  G +G      G +GE G++G
Sbjct: 438  AGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPA----GARGEPGNIG 493

Query: 537  LPGP------PGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGL---------PGPPG 581
             PGP      PG++G KG  G  G  G PG  G  G +GP GP G+         PGPPG
Sbjct: 494  FPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPG 553

Query: 582  RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAG 641
              G PG  G  GE G  GE+G  G  G PG  G  G++G PG SG AGP G  G  GP+G
Sbjct: 554  FQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSG 613

Query: 642  PPGVPGSVVQQ--------------EGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDG 687
            PPG  G+  +                GL GE+GA G  G +G  G PG RG IG  GRDG
Sbjct: 614  PPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDG 673

Query: 688  ------------PPGLQGLRGKKGDMGPPG------IPGLLGLQGPPGPPGVPGPPGPGG 729
                        P G  G RG+ G  GP G       PG  G  GP GP G  GP G  G
Sbjct: 674  ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAG 733

Query: 730  SPGLPGEIGFPGKPG------PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPG 783
             PG  GE G  G  G      P GP G  G  GPNGPPGP G++G+ G  G  G PG  G
Sbjct: 734  QPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAG 793

Query: 784  LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 843
              G  G  G++G PG  G AG  G  G  G +G  G  GE G +G PG  G++G  GEAG
Sbjct: 794  RTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAG 853

Query: 844  PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELG---PQGPTGPP 900
             AGPPG PG   L       PG  G  G +G+ GLPG  G  G PG LG   P G  GPP
Sbjct: 854  TAGPPGTPGPQGLLGA----PGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPP 909

Query: 901  GAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGS------------VGAPGLRGTPGKD 948
            GA G  G +GAPG AG  G PG+ G PG  G PG             VGA G  G  G  
Sbjct: 910  GAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPV 969

Query: 949  GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG----KGKDGEPGLRGSPGLPGPLGTK 1004
            G  G+ G  GE G  GPVGP G  G  G  GP G    KG+ GE G RG PGL G  G +
Sbjct: 970  GPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQ 1029

Query: 1005 AACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-------------GVAGPPG 1051
               G         + G    GD+GAPG  G  G RG  G              G  GP G
Sbjct: 1030 GLPG---------IAGH--HGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAG 1078

Query: 1052 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD 1105
              GP G +G  G  G PG PGP G +G     G  G+     +P  +  L P D
Sbjct: 1079 IRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKD 1132


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.144    0.458 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 120,368,460
Number of Sequences: 37866
Number of extensions: 10871053
Number of successful extensions: 461450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 736
Number of HSP's successfully gapped in prelim test: 1956
Number of HSP's that attempted gapping in prelim test: 40611
Number of HSP's gapped (non-prelim): 58634
length of query: 1626
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1510
effective length of database: 13,855,062
effective search space: 20921143620
effective search space used: 20921143620
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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