Guide to the Human Genome
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Search of human proteins with 39930511

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|39930511 collagen and calcium binding EGF domains 1 [Homo
sapiens]
         (406 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|39930511 collagen and calcium binding EGF domains 1 [Homo sap...   879   0.0  
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   102   5e-22
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   101   1e-21
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   101   1e-21
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   101   1e-21
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              101   1e-21
gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]      101   1e-21
gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]      101   1e-21
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      100   4e-21
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         99   7e-21
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    99   7e-21
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      99   9e-21
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    97   2e-20
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    97   2e-20
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    97   2e-20
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      97   2e-20
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                97   2e-20
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    97   3e-20
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    97   3e-20
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    97   3e-20
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    97   3e-20
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    97   3e-20
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    97   3e-20
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           97   3e-20
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]               96   4e-20
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       96   6e-20
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          96   6e-20
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     96   8e-20
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                96   8e-20
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 96   8e-20

>gi|39930511 collagen and calcium binding EGF domains 1 [Homo
           sapiens]
          Length = 406

 Score =  879 bits (2271), Expect = 0.0
 Identities = 406/406 (100%), Positives = 406/406 (100%)

Query: 1   MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL 60
           MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL
Sbjct: 1   MVPPPPSRGGAARGQLGRSLGPLLLLLALGHTWTYREEPEDGDREICSESKIATTKYPCL 60

Query: 61  KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD 120
           KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD
Sbjct: 61  KSSGELTTCYRKKCCKGYKFVLGQCIPEDYDVCAEAPCEQQCTDNFGRVLCTCYPGYRYD 120

Query: 121 RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY 180
           RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY
Sbjct: 121 RERHRKREKPYCLDIDECASSNGTLCAHICINTLGSYRCECREGYIREDDGKTCTRGDKY 180

Query: 181 PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA 240
           PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA
Sbjct: 181 PNDTGHEKSENMVKAGTCCATCKEFYQMKQTVLQLKQKIALLPNNAADLGKYITGDKVLA 240

Query: 241 SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
           SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG
Sbjct: 241 SNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR 360
           RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR
Sbjct: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHR 360

Query: 361 THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP 406
           THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP
Sbjct: 361 THSSAEEFPLPQEFPSYPEAMDLGSGDDHPRRTETRDLRAPRDFYP 406


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  102 bits (255), Expect = 5e-22
 Identities = 49/89 (55%), Positives = 54/89 (60%), Gaps = 2/89 (2%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           +PG PG  GG G  G PGP+G PGF G PG  G+PGPRG +GP G         QG RGP
Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKG--DQGERGP 395

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           VG PG  GR G KGE+G PG  G  G PG
Sbjct: 396 VGQPGPQGRQGPKGEQGPPGIPGPQGLPG 424



 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 46/96 (47%), Positives = 51/96 (53%), Gaps = 8/96 (8%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG QGP G PGP+G PG  G  G  G  GP+G  G  G   ++     G  GP 
Sbjct: 561 PGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPP 620

Query: 306 GPPGAPGR--------DGSKGERGAPGPRGSPGPPG 333
           G PG PGR        DG +G  GAPG  G PG PG
Sbjct: 621 GIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPG 656



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/90 (51%), Positives = 49/90 (54%), Gaps = 15/90 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           G PG+ G  G  G PGP G PG    PG+PGPPG PGP G  GP GP            G
Sbjct: 78  GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPP-----------G 125

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PVG PG  G  G KG+ G  GP G PGPPG
Sbjct: 126 PVGLPGEIGIRGPKGDPGPDGPSGPPGPPG 155



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 44/93 (47%), Positives = 53/93 (56%), Gaps = 9/93 (9%)

Query: 246 PGPPGLPGG---QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQG 300
           PGP G  G    QGPPG PGP+G PG  G  G PG+ GPRG +G  G +  P     ++G
Sbjct: 399 PGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPG----EKG 454

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG  G+ G +GE G PGP G  G PG
Sbjct: 455 EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPG 487



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 4/98 (4%)

Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPD 293
           V+ +   + GPPG  G  GPPG PG  GS G  G  GPPG+   PGP+G  G  GP  PD
Sbjct: 18  VVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPD 77

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGP 331
                 G  G  G PG  G  G KG+ G PGP G PGP
Sbjct: 78  GKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGP 115



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 53/125 (42%), Positives = 60/125 (48%), Gaps = 37/125 (29%)

Query: 245 LPGPPGLPGG--QGPPGSPGP------------KGSPGFPGMPGPPGQPGPRGSMGPM-- 288
           LPGPPGLPG    GPPG PGP            KG PG  G  GPPG PG  G  G +  
Sbjct: 106 LPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQG 165

Query: 289 ------------------GPSPDLSHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328
                             GP P L  +K   G+RG +G PG  G+ G KG+ GA G +G 
Sbjct: 166 LEGSADFLCPTNCPPGMKGP-PGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGI 224

Query: 329 PGPPG 333
           PGPPG
Sbjct: 225 PGPPG 229



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 45/93 (48%), Positives = 50/93 (53%), Gaps = 6/93 (6%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQGRR 302
           GPPG PG  G PGS G  G  G PG  GPPG  G  G  GP GP   P +  +   +G  
Sbjct: 33  GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEP 92

Query: 303 GPVGPPGAPGRDGSKGERGAPGP--RGSPGPPG 333
           GP+G PG  G+ G  G  G PGP   G PGPPG
Sbjct: 93  GPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPG 125



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 49/113 (43%), Positives = 58/113 (51%), Gaps = 10/113 (8%)

Query: 231 KYITGDKVLASNTYLPGPPGLPG--GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287
           K  TG   +      PG PG+ G  GQ G PGSPG +G  G PG PG  G PG +G  GP
Sbjct: 297 KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356

Query: 288 MG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333
            G      P     + G RG +GP G  G+ G +GER   G PGP+G  GP G
Sbjct: 357 QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKG 409



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 45/100 (45%), Positives = 53/100 (53%), Gaps = 17/100 (17%)

Query: 246 PGPPG---LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PGP G     G QG PG PGP+G  G+PGM GP G+ GP G  G +G          G  
Sbjct: 210 PGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIG-----ATGPP 264

Query: 303 GPVGPPGAPGRDGSKGERGAP---------GPRGSPGPPG 333
           G  GP G PGR G KG+ G+P         GP+G+ GPPG
Sbjct: 265 GEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPG 304



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 45/106 (42%), Positives = 55/106 (51%), Gaps = 19/106 (17%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHIK--- 298
           GPPG  G +GPPG  G KG  G PG+ GP G  GP+G+ GP G      +P    +K   
Sbjct: 262 GPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321

Query: 299 --------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333
                    G +G  G PG PG  G  G++G PGP+G P   GPPG
Sbjct: 322 GQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPG 367



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 42/92 (45%), Positives = 51/92 (55%), Gaps = 14/92 (15%)

Query: 245 LPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           +PGP GLPG +G  GSP   GP+G  G PG+ G PG+ G +G  G  GP           
Sbjct: 416 IPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGP----------- 464

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           +G  G  G PG  G  G+ GAPG +G PGPPG
Sbjct: 465 KGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPG 496



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 47/96 (48%), Positives = 49/96 (51%), Gaps = 20/96 (20%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GP G PG   P G  GPKG  G PG+PGP G PG +G  G  G        K G RG VG
Sbjct: 394 GPVGQPG---PQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG--------KTGPRGKVG 442

Query: 307 PPGA---PGRDGSKGERGAPGP------RGSPGPPG 333
            PG    PG  G KGE G PGP      RG PG PG
Sbjct: 443 DPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPG 478



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 49/139 (35%), Positives = 56/139 (40%), Gaps = 37/139 (26%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG--------- 283
           + G+K     +  PGP G  G +G PG PGP G  G PG+ G PG PGPRG         
Sbjct: 449 LPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPG 508

Query: 284 ---SMGPMGPSPDLSHIKQ-------------------------GRRGPVGPPGAPGRDG 315
                G  G      HI                           G  GP GPPG PG  G
Sbjct: 509 QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568

Query: 316 SKGERGAPGPRGSPGPPGS 334
            +G  G PGPRG PG  G+
Sbjct: 569 KQGPHGHPGPRGVPGIVGA 587



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 46/116 (39%), Positives = 55/116 (47%), Gaps = 16/116 (13%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGP- 290
           GD   +    +PGPPG  G +G PG  GPKG  G   + GM G  G  GP G  GP GP 
Sbjct: 214 GDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPP 273

Query: 291 ----------SPDLSHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                     SP +   +   G +G  GPPG  G+DG+ G  G  G  G  G PGS
Sbjct: 274 GRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS 329



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 43/101 (42%), Positives = 44/101 (43%), Gaps = 14/101 (13%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           + GDK     T   G  G PG  G PG  G KG     G PGP GQ G RG  G  GPS 
Sbjct: 425 VKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGE---SGEPGPKGQQGVRGEPGYPGPS- 480

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                     G  G PG  G  G  G RG  G RG PG PG
Sbjct: 481 ----------GDAGAPGVQGYPGPPGPRGLAGNRGVPGQPG 511



 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 37/94 (39%), Positives = 39/94 (41%), Gaps = 32/94 (34%)

Query: 255 QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPP------ 308
           +GPPG  GP      PG PGPPG PG  G  G  GP            G  GPP      
Sbjct: 26  RGPPGERGP------PGPPGPPGVPGSDGIDGDNGPP-----------GKAGPPGPKGEP 68

Query: 309 ---------GAPGRDGSKGERGAPGPRGSPGPPG 333
                    G PG DG  G +G PGP G PG  G
Sbjct: 69  GKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKG 102



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 26/52 (50%), Positives = 30/52 (57%), Gaps = 5/52 (9%)

Query: 245 LPGPPGLPGGQGPPGSP-----GPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
           +PGPPG+PG  G PG       G +GSPG PG  G PG PGP G  G   P+
Sbjct: 616 MPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPA 667



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 14/20 (70%), Positives = 14/20 (70%)

Query: 315 GSKGERGAPGPRGSPGPPGS 334
           G  GERG PGP G PG PGS
Sbjct: 27  GPPGERGPPGPPGPPGVPGS 46


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score =  101 bits (252), Expect = 1e-21
 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292
           LPGPPG PG  G  G+ GPKG  GFPG PGPPG+      PGP+G +      GPMGP P
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I  G +GP GPPG PG  G  G  G PG +G PGPPG
Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852



 Score =  101 bits (251), Expect = 1e-21
 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%)

Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PGPPG+PG +G PGS      PGPKG+PG+PG PG  G PGP G  GP+GP         
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200

Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333
           G  GP GPPG PG  G+        KGE+G  G +G PGPPG
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242



 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 58/113 (51%), Positives = 63/113 (55%), Gaps = 26/113 (23%)

Query: 246  PGPPGLPG--GQ----------GPPGSPGPKGSP---GFPGMPGPPGQP--------GPR 282
            PGPPGLPG  GQ          G PG PGPKG P   GFPG+ GPPG P        GP+
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 283  GSMGPMGP--SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ GP GP   P  +   QG  GP GPPG PG  G KGE+G PG  G PG PG
Sbjct: 1252 GNPGPQGPPGRPGPTGF-QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1303



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%)

Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298
           N   PGPPG+ G  GP G PGP G PG PG+   PGPPG PGP+G+MG     P     +
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333
           QG +GP GPPG           +  KG++G PG RG PGPPG
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%)

Query: 246  PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PG PG+      PG  G PG+PG KG PG PG PG PG PGP+G  GP G +P L     
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPVG  G PG+ G  GE+G PG  G PGP G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%)

Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283
           GD  L  +  LPG PGLPG           G G PG PGPKG PG PG PG PG PG  G
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333
             GP GP P     K        GP GPPG PG  G+   KG+RG PGP   PGPPG
Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
            PG PGL G  G PG PGPKG+PG PG PG  G PG +G++G MG P P       G  G 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 305  VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333
             G PG+PG  G KG++           G PGP+G PG PG
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298
           PGP G PG  GPPG+PG  G  G  G PGPPG PGP+G       GP GP P L   K  
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770

Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333
              +G RG  GPPG PGR   DG  G +G  GP G PGP G
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277
           P    D+G  + GD  L     LPG PG  G     G G PG PGPKG PG PG PG PG
Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG  G  GP GP        +      GPPG PG  G KG  G  G RG PGPPG
Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
           +PGPPG  G +GPPG PG  G+PG PGMPG  G PGP+G  G  G   +       G  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333
             GPPG PG  G KGE G+      PGP+G+PG PG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%)

Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           GPPGLPG       GPPG PGP G PG  G+PG  G PGP G   P  P    S    G 
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333
            GP+GPPG+PG  G  G  G PG +G       PGPPG
Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 246  PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PGP G+   PG  G PG PGP G  G PG PGPPG+ G  G  G  GP+       Q   
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPPG PG  G KG+ G PG  G+PG PG
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290
           I G+K       L G PGLPG  GP G PGP+G  G  G+PGPPG  G RG  G  G   
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333
           +P L  +  G  G  GP G PG +G+KGERG PG       +G PGPPG
Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%)

Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281
           G+K    +T  PGPPGL              G  G PG PG KG  GFPG+ GPPG PGP
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333
            G+  MGP GP P     ++G++G  GPPG   PG  G  G+ GAPG  G PGP G
Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293
           +PGPPG  G  G PG+PGP G PG PG+PG  G    PG +G MG MGP         P 
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340
            S +  G +G  G  G PG  G  GE+G+ G  G PGPPG  D  LL
Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266
            LP N       I G+K       LPG PGL G QGPP               G PG  G 
Sbjct: 1280 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1334

Query: 267  PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318
            PGFPGM GP   PG  GP G  G +GP      P  S      +G  GPPG PG+ G KG
Sbjct: 1335 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1394

Query: 319  ERGAPGPRGSPGPPG 333
              G  GP+G PGP G
Sbjct: 1395 LPGPQGPQGLPGPTG 1409



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/120 (40%), Positives = 58/120 (48%), Gaps = 20/120 (16%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPP--GSPGPKGSP---------GFPGMPGPPGQPGPRG 283
            G+K       +PGP G  G  G P  G+PGP G P         G PG+PG PG PGP+G
Sbjct: 1164 GEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKG 1223

Query: 284  S---------MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                       GP GP        +G +G  GP G PGR G  G +G PGP G PG PG+
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGN 1283



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300
           G PG  G  G PG PG  G PG+PG PG  G+ G +G  GP GP P L      + I  G
Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            +G +G PG PG  G +G  G  GP G PGPPG+
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298
           LPG PG PG  G PG PGPKG PG   F G  GPPG    PG  G++GPMGP P      
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
            G  GPVG  G  G  G+ G+ G PGP+G PG
Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293
           +PGPPGL G  G PG PGP G  G           PG PGPPG PG +G  G  G   D 
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334
                + I  G  GP G PG             PG+ G KG+ GA GP+G PG PG+
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%)

Query: 242  NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
            N  LPG PG  GG G PG PGP   KG PG  G+PGP GQ G  G  G   P P      
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 299  QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334
             G++G  G PG PG  G  G +G       PG +G PGPPGS
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%)

Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
           PG PGLPG  GPPGS                GPKG PG PG PG PG PG +G  G +  
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            P +   K G  G  G PG PG  G+ G+ G PG  G  G PG   F
Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           T L G PG  G  GP G PGP G PG PG+ G  G PGP G  GP+G  P L H   G +
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845

Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GP     PG PG  GS G  GAPGP G PG PG
Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283
           TG K L      PG PG PG +G PG     PG K      GSPG PG+PG PG PG  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP  +   I  +G RGP G PG PG  G+ G  G PG  G PGP G
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%)

Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273
           +P    D G+ IT        G+     +  LPG PGLPG  G PG PG KG PG PG+ 
Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706

Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322
           G PG PGP+G  G   P P  +    GR G  GPPG PG  G KGE G            
Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 323 PGPRGSPGPPGSFDF 337
           PG +G+ GP G   F
Sbjct: 765 PGFKGALGPKGDRGF 779



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 46/95 (48%), Positives = 53/95 (55%), Gaps = 13/95 (13%)

Query: 246  PGPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PG PG  G  GPPG PG    KG  G PG+PG PG PGP+G  G         H   G +
Sbjct: 1184 PGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG--------FHGFPGVQ 1234

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            GP GPPG+PG    +G +G PGP+G PG PG   F
Sbjct: 1235 GPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGF 1268



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%)

Query: 246  PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293
            PGPPGLPG  GQ        GPPG PG  G  G PG  GP G PGP G  G  G +  P 
Sbjct: 1362 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1421

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  G  G PG PG+ G++G  G PGP G  GPPG
Sbjct: 1422 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 13/103 (12%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIK- 298
            L GP G PG QGPPG PGP G  G PG  GPPG PG  G  G  G       P L  +K 
Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306

Query: 299  -QGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334
             QG  G  G PG PG +G KG+ G PG       +G  G PGS
Sbjct: 1307 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG+PG  G  G PGP+G  G PG  GPPG PG  G  G  G          GR+G  G
Sbjct: 1382 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1433

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             PG PG  G  G  G  G +G PGPPG+
Sbjct: 1434 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1461



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278
           K I G   L      PG PG+PG  G PG  G              GSPGFPG+ GPPG 
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148

Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG  G  G   P   +     G +G  G PG PG  G  G  G PGP G PGPPG
Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 49/110 (44%), Positives = 56/110 (50%), Gaps = 22/110 (20%)

Query: 246  PGPPG---LPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDL 294
            PGP G   LPG +GPPG PG    KG  G PG PG PG PG +G  GP G       P L
Sbjct: 1263 PGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGL 1322

Query: 295  SHIK-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            + +K            G +GP G PG+ G +G  G  G PGP G PGP G
Sbjct: 1323 NGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1372



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302
           PG PG PG  G  G PG  G PG PG+PG PG  G  G  G   P  P P      +G  
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339
           G  GPPGAPG  G  G  G PGP G PGP G   F L
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294
            PGP G+ G  GP G PG  GSPG PG  G            PG PGP+G  G  G  P  
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              IK G  G  G PG PG  G+KG+ G PG  G+PGPPG
Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%)

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308
           G+ G +G  G PG +G PG PG PGP G PGPRG  G  G P P       G +G  GPP
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95

Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG  G+ G  G PG  G+PGP G
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQG 120



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%)

Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293
           LPGP G+PG  GPPG PG      P G PG  G       GP G+ G +G  GP GP   
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332
           +S  K+              G RGP GPPG         G  G KGE+G PG RG PG  
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 333 G 333
           G
Sbjct: 304 G 304



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 39/88 (44%), Positives = 46/88 (52%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGP G+PG  G PG  G  G  G PG+PGP G+ G +G  G  GP   +     G +G  
Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG  G  G +G  G  G PG PG
Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPG 994



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%)

Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268
           LP    ++G    G K       L GPPG PG              +G  G PG +G PG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320
            PG+ GPPG P G +G  G  G       P  D  + + G  G  G PG PG  G  GE+
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 321 GAPGPRGSPGPPG 333
           G  G  G PGPPG
Sbjct: 331 GQKGDTGPPGPPG 343



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281
            + GD  L     LPGP G  G +G PG PGP           KG  G PG+PG PG  GP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 282  RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G  G          G+ G  G PG PG  G KG  G PG  G  GPPG
Sbjct: 981  KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PGPPG PG +G            PG PG  G PG PG+PGPPG  GP      + PS ++
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332
                   GP GPPG+PG  G +GE+G                       PG  G PGPP
Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 333 GSFDF 337
           GS  F
Sbjct: 506 GSLGF 510



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292
            G+  L     L GPPGL G  G  G PGP+G  G PG  G PGQPG  G  G  G    P
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 293  DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +S I   G  GP G PG PG  G+ G +G+ G  G PG PG+
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%)

Query: 245  LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293
            +PG  G+P      G QG PG PGP   KGS G PG+PGPPG   P   GS G  G  P 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970

Query: 294  LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I      +G +G  G PG PG  G  G  G PGP+G+PG PG
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%)

Query: 246  PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282
            PG PGLPG +G            PG PGPKG PG PG PG PG             PG  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 283  GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ G  G P    +    G +G  GPPG PG  G  G  G  G  G PGPPG
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%)

Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280
           PGPPG PG                      G G  G PG  G PG PG PG    PGQ G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330
            +G  G  GP        +G  G  G PGAPG  GSKGE          +G  G  GSPG
Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 331 PPG 333
            PG
Sbjct: 568 APG 570



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GQP    +    G SP       G +G  G  G PG +G  G  G PGP G PGP G
Sbjct: 21  GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score =  101 bits (252), Expect = 1e-21
 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292
           LPGPPG PG  G  G+ GPKG  GFPG PGPPG+      PGP+G +      GPMGP P
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I  G +GP GPPG PG  G  G  G PG +G PGPPG
Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852



 Score =  101 bits (251), Expect = 1e-21
 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%)

Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PGPPG+PG +G PGS      PGPKG+PG+PG PG  G PGP G  GP+GP         
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200

Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333
           G  GP GPPG PG  G+        KGE+G  G +G PGPPG
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242



 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 56/111 (50%), Positives = 60/111 (54%), Gaps = 28/111 (25%)

Query: 246  PGPPGLPG--GQ----------GPPGSPGPKGSPGFPGMPG------PPGQP-----GPR 282
            PGPPGLPG  GQ          G PG PGPKG PGF G PG      PPG P     GP+
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ GP GP       + G  GP GPPG PG  G KGE+G PG  G PG PG
Sbjct: 1252 GNPGPQGPPG-----RPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1297



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%)

Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298
           N   PGPPG+ G  GP G PGP G PG PG+   PGPPG PGP+G+MG     P     +
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333
           QG +GP GPPG           +  KG++G PG RG PGPPG
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%)

Query: 246  PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PG PG+      PG  G PG+PG KG PG PG PG PG PGP+G  GP G +P L     
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPVG  G PG+ G  GE+G PG  G PGP G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%)

Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283
           GD  L  +  LPG PGLPG           G G PG PGPKG PG PG PG PG PG  G
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333
             GP GP P     K        GP GPPG PG  G+   KG+RG PGP   PGPPG
Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
            PG PGL G  G PG PGPKG+PG PG PG  G PG +G++G MG P P       G  G 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 305  VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333
             G PG+PG  G KG++           G PGP+G PG PG
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298
           PGP G PG  GPPG+PG  G  G  G PGPPG PGP+G       GP GP P L   K  
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770

Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333
              +G RG  GPPG PGR   DG  G +G  GP G PGP G
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277
           P    D+G  + GD  L     LPG PG  G     G G PG PGPKG PG PG PG PG
Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG  G  GP GP        +      GPPG PG  G KG  G  G RG PGPPG
Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
           +PGPPG  G +GPPG PG  G+PG PGMPG  G PGP+G  G  G   +       G  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333
             GPPG PG  G KGE G+      PGP+G+PG PG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%)

Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           GPPGLPG       GPPG PGP G PG  G+PG  G PGP G   P  P    S    G 
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333
            GP+GPPG+PG  G  G  G PG +G       PGPPG
Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 246  PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PGP G+   PG  G PG PGP G  G PG PGPPG+ G  G  G  GP+       Q   
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPPG PG  G KG+ G PG  G+PG PG
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290
           I G+K       L G PGLPG  GP G PGP+G  G  G+PGPPG  G RG  G  G   
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333
           +P L  +  G  G  GP G PG +G+KGERG PG       +G PGPPG
Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%)

Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281
           G+K    +T  PGPPGL              G  G PG PG KG  GFPG+ GPPG PGP
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333
            G+  MGP GP P     ++G++G  GPPG   PG  G  G+ GAPG  G PGP G
Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293
           +PGPPG  G  G PG+PGP G PG PG+PG  G    PG +G MG MGP         P 
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340
            S +  G +G  G  G PG  G  GE+G+ G  G PGPPG  D  LL
Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266
            LP N       I G+K       LPG PGL G QGPP               G PG  G 
Sbjct: 1274 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1328

Query: 267  PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318
            PGFPGM GP   PG  GP G  G +GP      P  S      +G  GPPG PG+ G KG
Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388

Query: 319  ERGAPGPRGSPGPPG 333
              G  GP+G PGP G
Sbjct: 1389 LPGPQGPQGLPGPTG 1403



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/107 (45%), Positives = 56/107 (52%), Gaps = 19/107 (17%)

Query: 246  PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHI 297
            PG PGLPG +GPPG PG    KG  G PG PG PG PG +G  GP G       P L+ +
Sbjct: 1260 PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319

Query: 298  K-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            K            G +GP G PG+ G +G  G  G PGP G PGP G
Sbjct: 1320 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1366



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300
           G PG  G  G PG PG  G PG+PG PG  G+ G +G  GP GP P L      + I  G
Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            +G +G PG PG  G +G  G  GP G PGPPG+
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298
           LPG PG PG  G PG PGPKG PG   F G  GPPG    PG  G++GPMGP P      
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
            G  GPVG  G  G  G+ G+ G PGP+G PG
Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293
           +PGPPGL G  G PG PGP G  G           PG PGPPG PG +G  G  G   D 
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334
                + I  G  GP G PG             PG+ G KG+ GA GP+G PG PG+
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%)

Query: 242  NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
            N  LPG PG  GG G PG PGP   KG PG  G+PGP GQ G  G  G   P P      
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 299  QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334
             G++G  G PG PG  G  G +G       PG +G PGPPGS
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%)

Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
           PG PGLPG  GPPGS                GPKG PG PG PG PG PG +G  G +  
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            P +   K G  G  G PG PG  G+ G+ G PG  G  G PG   F
Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           T L G PG  G  GP G PGP G PG PG+ G  G PGP G  GP+G  P L H   G +
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845

Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GP     PG PG  GS G  GAPGP G PG PG
Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283
           TG K L      PG PG PG +G PG     PG K      GSPG PG+PG PG PG  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP  +   I  +G RGP G PG PG  G+ G  G PG  G PGP G
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%)

Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273
           +P    D G+ IT        G+     +  LPG PGLPG  G PG PG KG PG PG+ 
Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706

Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322
           G PG PGP+G  G   P P  +    GR G  GPPG PG  G KGE G            
Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 323 PGPRGSPGPPGSFDF 337
           PG +G+ GP G   F
Sbjct: 765 PGFKGALGPKGDRGF 779



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 49/107 (45%), Positives = 58/107 (54%), Gaps = 18/107 (16%)

Query: 246  PGPPGLPGG--QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--------PDLS 295
            PGPPG PG   +GP G+PGP+G PG PG+PGP G PG  G+ G  G          P L 
Sbjct: 1237 PGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1296

Query: 296  HIK--QGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334
             +K  QG  G  G PG PG +G KG+ G PG       +G  G PGS
Sbjct: 1297 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%)

Query: 246  PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293
            PGPPGLPG  GQ        GPPG PG  G  G PG  GP G PGP G  G  G +  P 
Sbjct: 1356 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1415

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  G  G PG PG+ G++G  G PGP G  GPPG
Sbjct: 1416 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1451



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG+PG  G  G PGP+G  G PG  GPPG PG  G  G  G          GR+G  G
Sbjct: 1376 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1427

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             PG PG  G  G  G  G +G PGPPG+
Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1455



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278
           K I G   L      PG PG+PG  G PG  G              GSPGFPG+ GPPG 
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148

Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG  G  G   P   +     G +G  G PG PG  G  G  G PGP G PGPPG
Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302
           PG PG PG  G  G PG  G PG PG+PG PG  G  G  G   P  P P      +G  
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339
           G  GPPGAPG  G  G  G PGP G PGP G   F L
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294
            PGP G+ G  GP G PG  GSPG PG  G            PG PGP+G  G  G  P  
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              IK G  G  G PG PG  G+KG+ G PG  G+PGPPG
Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%)

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308
           G+ G +G  G PG +G PG PG PGP G PGPRG  G  G P P       G +G  GPP
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95

Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG  G+ G  G PG  G+PGP G
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQG 120



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%)

Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293
           LPGP G+PG  GPPG PG      P G PG  G       GP G+ G +G  GP GP   
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332
           +S  K+              G RGP GPPG         G  G KGE+G PG RG PG  
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 333 G 333
           G
Sbjct: 304 G 304



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 5/92 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP----SPDLSHIKQGR 301
           PGP G+PG  G PG  G  G  G PG+PGP G+ G +G  G  GP     P+L   K G 
Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK-GE 965

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           +G  G PG PG  G KG +G PG  G PG  G
Sbjct: 966 KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSG 997



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%)

Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268
           LP    ++G    G K       L GPPG PG              +G  G PG +G PG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320
            PG+ GPPG P G +G  G  G       P  D  + + G  G  G PG PG  G  GE+
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 321 GAPGPRGSPGPPG 333
           G  G  G PGPPG
Sbjct: 331 GQKGDTGPPGPPG 343



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281
            + GD  L     LPGP G  G +G PG PGP           KG  G PG+PG PG  GP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 282  RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G  G          G+ G  G PG PG  G KG  G PG  G  GPPG
Sbjct: 981  KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PGPPG PG +G            PG PG  G PG PG+PGPPG  GP      + PS ++
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332
                   GP GPPG+PG  G +GE+G                       PG  G PGPP
Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 333 GSFDF 337
           GS  F
Sbjct: 506 GSLGF 510



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292
            G+  L     L GPPGL G  G  G PGP+G  G PG  G PGQPG  G  G  G    P
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 293  DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +S I   G  GP G PG PG  G+ G +G+ G  G PG PG+
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%)

Query: 245  LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293
            +PG  G+P      G QG PG PGP   KGS G PG+PGPPG   P   GS G  G  P 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970

Query: 294  LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I      +G +G  G PG PG  G  G  G PGP+G+PG PG
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%)

Query: 246  PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282
            PG PGLPG +G            PG PGPKG PG PG PG PG             PG  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 283  GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ G  G P    +    G +G  GPPG PG  G  G  G  G  G PGPPG
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%)

Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280
           PGPPG PG                      G G  G PG  G PG PG PG    PGQ G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330
            +G  G  GP        +G  G  G PGAPG  GSKGE          +G  G  GSPG
Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 331 PPG 333
            PG
Sbjct: 568 APG 570



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GQP    +    G SP       G +G  G  G PG +G  G  G PGP G PGP G
Sbjct: 21  GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score =  101 bits (252), Expect = 1e-21
 Identities = 55/101 (54%), Positives = 61/101 (60%), Gaps = 15/101 (14%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSM------GPMGPSP 292
           LPGPPG PG  G  G+ GPKG  GFPG PGPPG+      PGP+G +      GPMGP P
Sbjct: 755 LPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP-P 813

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I  G +GP GPPG PG  G  G  G PG +G PGPPG
Sbjct: 814 GLPGI--GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852



 Score =  101 bits (251), Expect = 1e-21
 Identities = 52/102 (50%), Positives = 60/102 (58%), Gaps = 19/102 (18%)

Query: 246 PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PGPPG+PG +G PGS      PGPKG+PG+PG PG  G PGP G  GP+GP         
Sbjct: 146 PGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG-----PP 200

Query: 300 GRRGPVGPPGAPGRDGS--------KGERGAPGPRGSPGPPG 333
           G  GP GPPG PG  G+        KGE+G  G +G PGPPG
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPG 242



 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 57/111 (51%), Positives = 60/111 (54%), Gaps = 25/111 (22%)

Query: 246  PGPPGLPG--GQ----------GPPGSPGPKGSPGFPGMPG------PPGQP-----GPR 282
            PGPPGLPG  GQ          G PG PGPKG PGF G PG      PPG P     GP+
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ GP GP        QG  GP GPPG PG  G KGE+G PG  G PG PG
Sbjct: 1252 GNPGPQGPPGRPGF--QGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG 1300



 Score = 97.8 bits (242), Expect = 2e-20
 Identities = 50/102 (49%), Positives = 59/102 (57%), Gaps = 10/102 (9%)

Query: 242 NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIK 298
           N   PGPPG+ G  GP G PGP G PG PG+   PGPPG PGP+G+MG     P     +
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGE 231

Query: 299 QGRRGPVGPPGAPGR-------DGSKGERGAPGPRGSPGPPG 333
           QG +GP GPPG           +  KG++G PG RG PGPPG
Sbjct: 232 QGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPG 273



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 49/94 (52%), Positives = 55/94 (58%), Gaps = 11/94 (11%)

Query: 246  PGPPGL------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PG PG+      PG  G PG+PG KG PG PG PG PG PGP+G  GP G +P L     
Sbjct: 1091 PGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPG-NPGL----P 1145

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPVG  G PG+ G  GE+G PG  G PGP G
Sbjct: 1146 GEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 58/117 (49%), Positives = 61/117 (52%), Gaps = 22/117 (18%)

Query: 235 GDKVLASNTYLPGPPGLPG-----------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRG 283
           GD  L  +  LPG PGLPG           G G PG PGPKG PG PG PG PG PG  G
Sbjct: 675 GDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIG 734

Query: 284 SMGPMGPSPDLSHIKQ----GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPG 333
             GP GP P     K        GP GPPG PG  G+   KG+RG PGP   PGPPG
Sbjct: 735 LEGPPGP-PGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGP---PGPPG 787



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 48/100 (48%), Positives = 56/100 (56%), Gaps = 12/100 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
            PG PGL G  G PG PGPKG+PG PG PG  G PG +G++G MG P P       G  G 
Sbjct: 990  PGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGV 1049

Query: 305  VGPPGAPGRDGSKGER-----------GAPGPRGSPGPPG 333
             G PG+PG  G KG++           G PGP+G PG PG
Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 52/101 (51%), Positives = 56/101 (55%), Gaps = 14/101 (13%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS-----MGPMGPSPDLSHIK-- 298
           PGP G PG  GPPG+PG  G  G  G PGPPG PGP+G       GP GP P L   K  
Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGP-PGLPGFKGA 770

Query: 299 ---QGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPG 333
              +G RG  GPPG PGR   DG  G +G  GP G PGP G
Sbjct: 771 LGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMG 811



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 54/116 (46%), Positives = 57/116 (49%), Gaps = 7/116 (6%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPG 277
           P    D+G  + GD  L     LPG PG  G     G G PG PGPKG PG PG PG PG
Sbjct: 671 PGRDGDVG--LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG  G  GP GP        +      GPPG PG  G KG  G  G RG PGPPG
Sbjct: 729 TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 48/96 (50%), Positives = 56/96 (58%), Gaps = 7/96 (7%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
           +PGPPG  G +GPPG PG  G+PG PGMPG  G PGP+G  G  G   +       G  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 304 PVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333
             GPPG PG  G KGE G+      PGP+G+PG PG
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 48/98 (48%), Positives = 52/98 (53%), Gaps = 11/98 (11%)

Query: 247 GPPGLPG-----GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           GPPGLPG       GPPG PGP G PG  G+PG  G PGP G   P  P    S    G 
Sbjct: 811 GPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGA 870

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGS------PGPPG 333
            GP+GPPG+PG  G  G  G PG +G       PGPPG
Sbjct: 871 PGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 45/91 (49%), Positives = 50/91 (54%), Gaps = 3/91 (3%)

Query: 246  PGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PGP G+   PG  G PG PGP G  G PG PGPPG+ G  G  G  GP+       Q   
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GPPG PG  G KG+ G PG  G+PG PG
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG 1220



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 52/109 (47%), Positives = 60/109 (55%), Gaps = 9/109 (8%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--P 290
           I G+K       L G PGLPG  GP G PGP+G  G  G+PGPPG  G RG  G  G   
Sbjct: 43  IKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPG 102

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333
           +P L  +  G  G  GP G PG +G+KGERG PG       +G PGPPG
Sbjct: 103 TPGLPGM-PGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 54/116 (46%), Positives = 63/116 (54%), Gaps = 19/116 (16%)

Query: 235 GDKVLASNTYLPGPPGL-------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281
           G+K    +T  PGPPGL              G  G PG PG KG  GFPG+ GPPG PGP
Sbjct: 328 GEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGP 387

Query: 282 RGS--MGPMGPSPDLSHIKQGRRGPVGPPG--APGRDGSKGERGAPGPRGSPGPPG 333
            G+  MGP GP P     ++G++G  GPPG   PG  G  G+ GAPG  G PGP G
Sbjct: 388 PGAAVMGPPGP-PGFPG-ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 50/107 (46%), Positives = 58/107 (54%), Gaps = 12/107 (11%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS--------PD 293
           +PGPPG  G  G PG+PGP G PG PG+PG  G    PG +G MG MGP         P 
Sbjct: 855 VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG 914

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340
            S +  G +G  G  G PG  G  GE+G+ G  G PGPPG  D  LL
Sbjct: 915 RSGV-PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLL 960



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 57/135 (42%), Positives = 62/135 (45%), Gaps = 28/135 (20%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPP---------------GSPGPKGS 266
            LP N       I G+K       LPG PGL G QGPP               G PG  G 
Sbjct: 1277 LPGNGG-----IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGV 1331

Query: 267  PGFPGMPGP---PGQPGPRGSMGPMGPS-----PDLSHIKQGRRGPVGPPGAPGRDGSKG 318
            PGFPGM GP   PG  GP G  G +GP      P  S      +G  GPPG PG+ G KG
Sbjct: 1332 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1391

Query: 319  ERGAPGPRGSPGPPG 333
              G  GP+G PGP G
Sbjct: 1392 LPGPQGPQGLPGPTG 1406



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 7/94 (7%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL------SHIKQG 300
           G PG  G  G PG PG  G PG+PG PG  G+ G +G  GP GP P L      + I  G
Sbjct: 298 GKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGP-PGLVIPRPGTGITIG 356

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            +G +G PG PG  G +G  G  GP G PGPPG+
Sbjct: 357 EKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGA 390



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/92 (52%), Positives = 53/92 (57%), Gaps = 12/92 (13%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIK 298
           LPG PG PG  G PG PGPKG PG   F G  GPPG    PG  G++GPMGP P      
Sbjct: 571 LPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP-PGF---- 625

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
            G  GPVG  G  G  G+ G+ G PGP+G PG
Sbjct: 626 -GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 49/117 (41%), Positives = 56/117 (47%), Gaps = 27/117 (23%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMGPMGPSPD- 293
           +PGPPGL G  G PG PGP G  G           PG PGPPG PG +G  G  G   D 
Sbjct: 418 IPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDK 477

Query: 294 ----LSHIKQGRRGPVGPPGA------------PGRDGSKGERGAPGPRGSPGPPGS 334
                + I  G  GP G PG             PG+ G KG+ GA GP+G PG PG+
Sbjct: 478 GDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGA 534



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 48/102 (47%), Positives = 53/102 (51%), Gaps = 9/102 (8%)

Query: 242  NTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
            N  LPG PG  GG G PG PGP   KG PG  G+PGP GQ G  G  G   P P      
Sbjct: 1141 NPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGL 1200

Query: 299  QGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPGS 334
             G++G  G PG PG  G  G +G       PG +G PGPPGS
Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGS 1242



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 47/107 (43%), Positives = 52/107 (48%), Gaps = 16/107 (14%)

Query: 246 PGPPGLPGGQGPPGS---------------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
           PG PGLPG  GPPGS                GPKG PG PG PG PG PG +G  G +  
Sbjct: 493 PGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT 552

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            P +   K G  G  G PG PG  G+ G+ G PG  G  G PG   F
Sbjct: 553 FPGMKGDK-GELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/96 (52%), Positives = 53/96 (55%), Gaps = 8/96 (8%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           T L G PG  G  GP G PGP G PG PG+ G  G PGP G  GP+G  P L H   G +
Sbjct: 789 TGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIG-QPGL-HGIPGEK 845

Query: 303 GPVGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GP     PG PG  GS G  GAPGP G PG PG
Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG 881



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 12/111 (10%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGS----PGPK------GSPGFPGMPGPPGQPGPRG 283
           TG K L      PG PG PG +G PG     PG K      GSPG PG+PG PG PG  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 284 SMGPMGPSPDLSHIK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP  +   I  +G RGP G PG PG  G+ G  G PG  G PGP G
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVG 632



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 56/135 (41%), Positives = 65/135 (48%), Gaps = 22/135 (16%)

Query: 222 LPNNAADLGKYIT--------GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMP 273
           +P    D G+ IT        G+     +  LPG PGLPG  G PG PG KG PG PG+ 
Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI- 706

Query: 274 GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG-----------A 322
           G PG PGP+G  G   P P  +    GR G  GPPG PG  G KGE G            
Sbjct: 707 GLPGPPGPKGFPGI--PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764

Query: 323 PGPRGSPGPPGSFDF 337
           PG +G+ GP G   F
Sbjct: 765 PGFKGALGPKGDRGF 779



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 48/107 (44%), Positives = 55/107 (51%), Gaps = 19/107 (17%)

Query: 246  PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMG-----PSPDLSHI 297
            PG  GLPG +GPPG PG    KG  G PG PG PG PG +G  GP G       P L+ +
Sbjct: 1263 PGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322

Query: 298  K-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            K            G +GP G PG+ G +G  G  G PGP G PGP G
Sbjct: 1323 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG 1369



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 16/100 (16%)

Query: 246  PGPPGLPG--GQ--------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PD 293
            PGPPGLPG  GQ        GPPG PG  G  G PG  GP G PGP G  G  G +  P 
Sbjct: 1359 PGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPG 1418

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  G  G PG PG+ G++G  G PGP G  GPPG
Sbjct: 1419 F----DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 8/88 (9%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG+PG  G  G PGP+G  G PG  GPPG PG  G  G  G          GR+G  G
Sbjct: 1379 GPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG--------GRKGDPG 1430

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             PG PG  G  G  G  G +G PGPPG+
Sbjct: 1431 LPGQPGTRGLDGPPGPDGLQGPPGPPGT 1458



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 49/115 (42%), Positives = 53/115 (46%), Gaps = 14/115 (12%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP------------KGSPGFPGMPGPPGQ 278
           K I G   L      PG PG+PG  G PG  G              GSPGFPG+ GPPG 
Sbjct: 89  KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGP 148

Query: 279 PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG  G  G   P   +     G +G  G PG PG  G  G  G PGP G PGPPG
Sbjct: 149 PGIPGMKGE--PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/97 (48%), Positives = 49/97 (50%), Gaps = 9/97 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSHIKQGRR 302
           PG PG PG  G  G PG  G PG PG+PG PG  G  G  G   P  P P      +G  
Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP------KGFP 718

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339
           G  GPPGAPG  G  G  G PGP G PGP G   F L
Sbjct: 719 GIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 47/99 (47%), Positives = 52/99 (52%), Gaps = 13/99 (13%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMGPMGPSPDL 294
            PGP G+ G  GP G PG  GSPG PG  G            PG PGP+G  G  G  P  
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG-YPGN 1093

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              IK G  G  G PG PG  G+KG+ G PG  G+PGPPG
Sbjct: 1094 PGIK-GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 42/85 (49%), Positives = 48/85 (56%), Gaps = 7/85 (8%)

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP 308
           G+ G +G  G PG +G PG PG PGP G PGPRG  G  G P P       G +G  GPP
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGP------PGPKGIRGPP 95

Query: 309 GAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG  G+ G  G PG  G+PGP G
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQG 120



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 50/121 (41%), Positives = 56/121 (46%), Gaps = 32/121 (26%)

Query: 245 LPGPPGLPGGQGPPGSPG------PKGSPGFPG-----MPGPPGQPGPRGSMGPMGPSPD 293
           LPGP G+PG  GPPG PG      P G PG  G       GP G+ G +G  GP GP   
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 294 LSHIKQ--------------GRRGPVGPPG-------APGRDGSKGERGAPGPRGSPGPP 332
           +S  K+              G RGP GPPG         G  G KGE+G PG RG PG  
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 333 G 333
           G
Sbjct: 304 G 304



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 46/91 (50%), Positives = 51/91 (56%), Gaps = 3/91 (3%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRR 302
            L GP G PG QGPPG PG +G PG  G PG PG  G +G  G  G    P L  +K G +
Sbjct: 1247 LEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK-GDQ 1305

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP G  G PGR G  G +G PG  G PG PG
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1336



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 39/88 (44%), Positives = 46/88 (52%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGP G+PG  G PG  G  G  G PG+PGP G+ G +G  G  GP   +     G +G  
Sbjct: 907 PGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEK 966

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG  G  G +G  G  G PG PG
Sbjct: 967 GEPGLPGIPGVSGPKGYQGLPGDPGQPG 994



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 50/133 (37%), Positives = 59/133 (44%), Gaps = 21/133 (15%)

Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGG-------------QGPPGSPGPKGSPG 268
           LP    ++G    G K       L GPPG PG              +G  G PG +G PG
Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270

Query: 269 FPGMPGPPGQP-GPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER 320
            PG+ GPPG P G +G  G  G       P  D  + + G  G  G PG PG  G  GE+
Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330

Query: 321 GAPGPRGSPGPPG 333
           G  G  G PGPPG
Sbjct: 331 GQKGDTGPPGPPG 343



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 47/112 (41%), Positives = 52/112 (46%), Gaps = 19/112 (16%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGP-----------KGSPGFPGMPGPPGQPGP 281
            + GD  L     LPGP G  G +G PG PGP           KG  G PG+PG PG  GP
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 282  RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G  G          G+ G  G PG PG  G KG  G PG  G  GPPG
Sbjct: 981  KGYQGLPG--------DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG 1024



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/125 (38%), Positives = 56/125 (44%), Gaps = 43/125 (34%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PGPPG PG +G            PG PG  G PG PG+PGPPG  GP      + PS ++
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH-----IPPSDEI 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGA----------------------PGPRGSPGPP 332
                   GP GPPG+PG  G +GE+G                       PG  G PGPP
Sbjct: 451 C-----EPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPP 505

Query: 333 GSFDF 337
           GS  F
Sbjct: 506 GSLGF 510



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 47/103 (45%), Positives = 54/103 (52%), Gaps = 3/103 (2%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SP 292
            G+  L     L GPPGL G  G  G PGP+G  G PG  G PGQPG  G  G  G    P
Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068

Query: 293  DLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +S I   G  GP G PG PG  G+ G +G+ G  G PG PG+
Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 49/105 (46%), Positives = 56/105 (53%), Gaps = 17/105 (16%)

Query: 245  LPGPPGLP------GGQGPPGSPGP---KGSPGFPGMPGPPGQPGPR--GSMGPMGPSPD 293
            +PG  G+P      G QG PG PGP   KGS G PG+PGPPG   P   GS G  G  P 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG-EPG 970

Query: 294  LSHI-----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            L  I      +G +G  G PG PG  G  G  G PGP+G+PG PG
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG 1015



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 47/112 (41%), Positives = 51/112 (45%), Gaps = 24/112 (21%)

Query: 246  PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPG------------QPGPR 282
            PG PGLPG +G            PG PGPKG PG PG PG PG             PG  
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 283  GSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G+ G  G P    +    G +G  GPPG PG  G  G  G  G  G PGPPG
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 48/123 (39%), Positives = 51/123 (41%), Gaps = 43/123 (34%)

Query: 246 PGPPGLPG----------------------GQGPPGSPGPKGSPGFPGMPGP---PGQPG 280
           PGPPG PG                      G G  G PG  G PG PG PG    PGQ G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGE----------RGAPGPRGSPG 330
            +G  G  GP        +G  G  G PGAPG  GSKGE          +G  G  GSPG
Sbjct: 516 EKGQAGATGP--------KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPG 567

Query: 331 PPG 333
            PG
Sbjct: 568 APG 570



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 23/57 (40%), Positives = 26/57 (45%), Gaps = 2/57 (3%)

Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GQP    +    G SP       G +G  G  G PG +G  G  G PGP G PGP G
Sbjct: 21  GQPAEAAAC--YGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRG 75


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  101 bits (251), Expect = 1e-21
 Identities = 60/134 (44%), Positives = 70/134 (52%), Gaps = 30/134 (22%)

Query: 245  LPGPPGLPGGQG------PPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMGPSPDLS 295
            L G PG+ G +G      PPG PGPKGS G PGMP   G PG+PGP+G  G  GP P + 
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGP-PGMR 1059

Query: 296  HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEK 355
              K GRRGP GP G  G  GS+G +G PGP+G PG PG                   Q+ 
Sbjct: 1060 GAK-GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG-------------------QQG 1099

Query: 356  VFGHRTHSSAEEFP 369
            V G R H  +  FP
Sbjct: 1100 VAGERGHLGSRGFP 1113



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 51/106 (48%), Positives = 60/106 (56%), Gaps = 7/106 (6%)

Query: 235  GDKVLASNTYLPGP------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPM 288
            GD+ +     +PGP      PG+PGG G PG PGP+G PG  G PG  G  G RG  GP 
Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071

Query: 289  GPSPDL-SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+ +  S   +G  GP G PG PG+ G  GERG  G RG PG PG
Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 58/118 (49%), Positives = 64/118 (54%), Gaps = 11/118 (9%)

Query: 229  LGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSM 285
            LGK   GDK        PGP G PG  GPPG  GP   KG PG  G+PGP GQ GP G  
Sbjct: 891  LGK--VGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE 948

Query: 286  GPMGP--SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLM 341
            GPMGP  +P L    +G+ G  G PG PG DG KGE G PG  G  G  G   F+ L+
Sbjct: 949  GPMGPPGAPGL----EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 48/92 (52%), Positives = 55/92 (59%), Gaps = 5/92 (5%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           LPGPPGLPG  G PG+ GP+G PG  G PG PG PG +G  G  G SP  +H   G +G 
Sbjct: 635 LPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAH--DGAKGD 692

Query: 305 VGPPGA---PGRDGSKGERGAPGPRGSPGPPG 333
           +G PG    PG  G KG +G PGP G PG  G
Sbjct: 693 MGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG 724



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/131 (38%), Positives = 59/131 (45%), Gaps = 29/131 (22%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------------- 278
           GD  L     LPG PG+PG +GP G PGP G+PG PG PG  GQ                
Sbjct: 631 GDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAK 690

Query: 279 -----------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
                      PGP G  G  G      H   G +G  GP G+PG  G  G +G PGP G
Sbjct: 691 GDMGLPGLSGNPGPPGRKGHKGYPGPAGH--PGEQGQPGPEGSPGAKGYPGRQGLPGPVG 748

Query: 328 SPGPPGSFDFL 338
            PGP GS  ++
Sbjct: 749 DPGPKGSRGYI 759



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 56/131 (42%), Positives = 64/131 (48%), Gaps = 24/131 (18%)

Query: 222 LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQ 278
           +P  + D G    GDK    +  LPG PG  G  GP G  G KGS GFPG PGP   PG 
Sbjct: 860 VPGVSGDPG--FQGDK---GSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGD 914

Query: 279 PGPRGSMGPMG----------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP----- 323
            GP G  GP G          P P      +G  GP+GPPGAPG +G  G +G P     
Sbjct: 915 IGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGL 974

Query: 324 -GPRGSPGPPG 333
            G +G PG PG
Sbjct: 975 DGVKGEPGDPG 985



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 48/91 (52%), Positives = 53/91 (58%), Gaps = 5/91 (5%)

Query: 246 PGPPGLPGGQGPPG---SPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PGP G PG QG PG   SPG KG PG  G+PGP G PGP+GS G +G  P L  +  G  
Sbjct: 714 PGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIG-LPGLFGL-PGSD 771

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G PG PG+ G  G  G PG  G  GPPG
Sbjct: 772 GERGLPGVPGKRGKMGMPGFPGVFGERGPPG 802



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 48/100 (48%), Positives = 52/100 (52%), Gaps = 20/100 (20%)

Query: 246  PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGSMGPMGPSPD 293
            PGP   PG PG QG  G  G  GS GFPG+PGP         PG+PGP+G  GP+GP   
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP--- 1142

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  GP GPPGA G  G  GE G  G  G  G PG
Sbjct: 1143 -----PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPG 1177



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 44/97 (45%), Positives = 52/97 (53%), Gaps = 10/97 (10%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI--------- 297
            GP G PG  G  G PG KG PG PG+ G  G+PG  G  GP+G    +  I         
Sbjct: 949  GPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIV 1008

Query: 298  -KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             ++G RG +GPPG PG  GS G  G PG  G+PG PG
Sbjct: 1009 GEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 46/101 (45%), Positives = 53/101 (52%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------ 299
            PGP G  G  GPPG  GPKG PG  G PG PG+ G +G +GP+G   +   I Q      
Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190

Query: 300  -GRRGPVGPPGA------PGRDGSKGERGAPGPRGSPGPPG 333
             G  GP+GP G       PG DG  GE+G  G  G  GPPG
Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 49/101 (48%), Positives = 57/101 (56%), Gaps = 14/101 (13%)

Query: 239 LASNTYLP---GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLS 295
           LA +T  P   GPPG  G  G PG PG  G PG PG  GP G PGP G+ G  GP     
Sbjct: 614 LAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGP----- 668

Query: 296 HIKQGRRGPVGPPG-APGR--DGSKGERGAPGPRGSPGPPG 333
               G +G  G PG +PG+  DG+KG+ G PG  G+PGPPG
Sbjct: 669 ---PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPG 706



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 52/114 (45%), Positives = 58/114 (50%), Gaps = 17/114 (14%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP---RGSMGPMGPS 291
            G +     T LPG  G PG +G PG  G  G PG  G+ GP G PG    +G  GP GP 
Sbjct: 1505 GKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP- 1563

Query: 292  PDLSHIKQGRRGP---VGPPGAPGRDGSKGE---------RGAPGPRGSPGPPG 333
            P L   K+G  GP   +GP G PG  G KG          RG PGPRG PGPPG
Sbjct: 1564 PGLMG-KEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPG 1616



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 45/92 (48%), Positives = 49/92 (53%), Gaps = 6/92 (6%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-----SPDLSHIKQGR 301
            G  G PG  GP G PG KG PG PG  GP G  GP G MGP GP      P L   + G 
Sbjct: 1108 GSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG-EAGM 1166

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G +GP G PG  G  G+RG PG  G  GP G
Sbjct: 1167 KGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG 1198



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 49/118 (41%), Positives = 58/118 (49%), Gaps = 31/118 (26%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG------------------FPGMPGPPGQPGPRGSMGP 287
            PGPPG+ G +GP G  G +G  G                   PG PGPPG PGP+GS G 
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 288  MGPS-----------PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPG-PRGSPGPPG 333
            +GP+           P L+    G +G VGP G PG  G KGE+G  G   G PGPPG
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGY-DGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPG 1346



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 46/97 (47%), Positives = 52/97 (53%), Gaps = 10/97 (10%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMP---------GPPGQPGPRGSMGPMG-PSPDLSH 296
            GPPG PG +GP G  G +G PG PG P         G PGQ G  G  GP G P P  S 
Sbjct: 1340 GPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSK 1399

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              +G +G  G  GAPGR G +G +G PGPRG  G  G
Sbjct: 1400 GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQG 1436



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 45/94 (47%), Positives = 52/94 (55%), Gaps = 10/94 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGRR 302
           G  G+PG  G PG  G KGS G PG PG  G+PGP G +G  G    P P      +G  
Sbjct: 856 GEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPP---GPEGFP 912

Query: 303 GPVGPPGAPGRDGSKGE---RGAPGPRGSPGPPG 333
           G +GPPG  G +G KG+   RG PGPRG  GP G
Sbjct: 913 GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEG 946



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 53/120 (44%), Positives = 61/120 (50%), Gaps = 16/120 (13%)

Query: 221 LLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPG 277
           L P  A D  K   GD  L   +  PGPPG  G +G   P G PG +G PG  G PG  G
Sbjct: 680 LSPGKAHDGAK---GDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKG 736

Query: 278 QPGPRGSMGPMG-PSPDLSHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333
            PG +G  GP+G P P      +G RG +G P   G PG DG +G  G PG RG  G PG
Sbjct: 737 YPGRQGLPGPVGDPGP------KGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPG 790



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 45/110 (40%), Positives = 52/110 (47%), Gaps = 22/110 (20%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--------SPDLSHI 297
            PG PG PG +G  G  G  G  G PG PGP G PGP+GS G  GP        +P    +
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV 1419

Query: 298  --------------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                          +QG  G  GP G PGRDG  G++G  G  G PGP G
Sbjct: 1420 QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMG 1469



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 50/124 (40%), Positives = 59/124 (47%), Gaps = 35/124 (28%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---------------FPGMPGPPGQPGPRGSMG---- 286
            PGPPG PG +G  GS GP G+PG                 G+ GP G PGP+G  G    
Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGE 1334

Query: 287  ------PMGPSPDLSHI-KQGRRGPVGPPGAPGRDGSKGERGAPG---------PRGSPG 330
                  P GP  D   +  +G RG  G PG PG++G +G RG PG         PRG PG
Sbjct: 1335 DGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPG 1394

Query: 331  PPGS 334
            P GS
Sbjct: 1395 PKGS 1398



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 45/99 (45%), Positives = 51/99 (51%), Gaps = 14/99 (14%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSM---------GPMGPSPDL 294
            G  GLPG  GPPG  G +G  G P   G PG  GQPG  G M         GP GP  D+
Sbjct: 1493 GESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDI 1552

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                +G +GP GPPG  G++G  G  G  GP G PGP G
Sbjct: 1553 GF--KGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKG 1589



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 54/111 (48%), Positives = 57/111 (51%), Gaps = 26/111 (23%)

Query: 247  GPPGLPGGQGPPGS---PGPKGSPGFPGMPG------PPGQPGPRGSMGPMGPSPDLSHI 297
            G  GLPG QG PGS   PG  G  GFPGM G      PPG  G +G  GP GP P L   
Sbjct: 1511 GRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP-PGLMG- 1568

Query: 298  KQGRRGPVG---PPGAPGRDGSKGERG---------APGPRGS---PGPPG 333
            K+G  GP+G   P G PG  G KG RG          PGPRG    PGPPG
Sbjct: 1569 KEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 43/90 (47%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            LPGP G+ G QG  G  GP G PG  G  G  G+ G  G  GPMGP+      K+G  G 
Sbjct: 1425 LPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAG-----KRGNPGV 1479

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             G PGA G  G KGE G PG  G PG  G+
Sbjct: 1480 AGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 42/90 (46%), Positives = 51/90 (56%), Gaps = 7/90 (7%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
           +PG PG+ G +GPPG  G  G  G PG PG PG  G  G +GP+G P P      +G +G
Sbjct: 788 MPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGP------KGMKG 841

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG  G KGE+G PG  G PG  G
Sbjct: 842 LMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 47/102 (46%), Positives = 51/102 (50%), Gaps = 11/102 (10%)

Query: 245 LPGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
           LPGPPG+PG        GP G PGPKG  G  G  G PG  G +G  G  G S D     
Sbjct: 812 LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGF-- 869

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGS---PGPPGSFDF 337
           QG +G  G PG PG  G  G  G  G +GS   PGPPG   F
Sbjct: 870 QGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGF 911



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/94 (46%), Positives = 52/94 (55%), Gaps = 11/94 (11%)

Query: 246  PGPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PG PGL G +G PG PG       +G  GF G+ G PG  G +G  G MGP P +     
Sbjct: 969  PGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGP-PGV----P 1023

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +G +G PG PG  G+ GE G  GP GS GPPG
Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 42/99 (42%), Positives = 48/99 (48%), Gaps = 2/99 (2%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+  L  ++   GP GL G +G PG  G  G  G  G+ G  G PGP G  G  GP    
Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               KQG +G  G  GA G  G  GE G PG  G PG PG
Sbjct: 1246 G--KQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPG 1282



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP------GPRGSMGPMG-PSPDLSHI 297
            +PG PG PG  GP GS G  G  G PG  G  G+P      G +G +GP+G P P     
Sbjct: 1271 VPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKG 1330

Query: 298  KQGR----RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +QG      GP GPPG  G  G +G+RG PG  G PG  G
Sbjct: 1331 EQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEG 1370



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 41/98 (41%), Positives = 51/98 (52%), Gaps = 11/98 (11%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHIKQGRRG 303
            GPPG  G +G  G PG +G PG  G PG  G+   PG  G  GP GP  D+    +G +G
Sbjct: 1502 GPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF--KGIQG 1559

Query: 304  PVGPPGAPGRDGSKGE------RGAPGPRGSPGPPGSF 335
            P GPPG  G++G  G        G PGP+G  G  G +
Sbjct: 1560 PRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDW 1597



 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 42/105 (40%), Positives = 47/105 (44%), Gaps = 20/105 (19%)

Query: 245  LPGPPGLPG-----GQ-------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            + GP GLPG     GQ       G PG  GP G  G PG+ G PG  GP G  G  G   
Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESG--- 1496

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
                   G+ GP G  G  GR G  G +G PG +G PG  G   F
Sbjct: 1497 -----LPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 39/99 (39%), Positives = 50/99 (50%), Gaps = 11/99 (11%)

Query: 245  LPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
            LPG  G+ G  GP G+PG       +G PG  G  GP G  G +G  G   P PD  H +
Sbjct: 1160 LPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRG--DPGPDGEHGE 1217

Query: 299  QGRRGPV---GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            +G+ G +   GPPG PG  G +G  G  G +G  G  G+
Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGA 1256



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 23/48 (47%), Positives = 27/48 (56%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280
            I G   +   + LPGP G  G +G  G  GP+G PG  G PGPPG PG
Sbjct: 1572 IVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/50 (46%), Positives = 25/50 (50%), Gaps = 11/50 (22%)

Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           MGP GP           +G  G PG PG  G  G  GA GPRG PGP G+
Sbjct: 624 MGPPGP-----------KGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGN 662



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 18/36 (50%), Positives = 19/36 (52%)

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
           G  GP G  G PG  G  G  G PG RG  GPPG +
Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPY 660


>gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]
          Length = 654

 Score =  101 bits (251), Expect = 1e-21
 Identities = 46/88 (52%), Positives = 55/88 (62%), Gaps = 8/88 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG +GPPG  G  G  G PG+PG PG+PG +G MGP+GP         G++G +
Sbjct: 197 PGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGP--------PGQKGSI 248

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG +G KGE G PG  G  G PG
Sbjct: 249 GAPGIPGMNGQKGEPGLPGAVGQNGIPG 276



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 12/118 (10%)

Query: 228 DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGP 281
           D G    G K     +  PG  G PG  G PG PG KG PGF      PG+PG PG  G 
Sbjct: 304 DPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE 363

Query: 282 RGSMGPMG------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           RG  GP G      P       KQG  G  GP G+ G  G KG+ GA GPRG PG  G
Sbjct: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKG 421



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 53/117 (45%), Positives = 64/117 (54%), Gaps = 12/117 (10%)

Query: 222 LPNNAADLGKY-ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280
           L  +  D+G   +TG+K       LPG  G+ G +G  G PGP+G P   G PGPPG  G
Sbjct: 480 LKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHG 538

Query: 281 PRGSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
           P G MGP G P P      +G  GP+GP G  G  G +GE+GA   PGPRG  G PG
Sbjct: 539 PPGPMGPHGLPGP------KGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 16/103 (15%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH---------I 297
           GPPG  G +G  G  GP G PG  G PGP G  G +G  GP    P ++H         I
Sbjct: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182

Query: 298 K-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           K       QG+ GP GPPG PG  G  G+ G  GPRG PG PG
Sbjct: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 16/95 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG PG QG  G  G +GSPG PGM G  G  G +G MG  G +        G +G +G
Sbjct: 449 GPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMT--------GEKGGIG 500

Query: 307 PPGAPGRDGSKGER---GAPGPR-----GSPGPPG 333
            PG PG +G KGE+   G PGP+     G PGPPG
Sbjct: 501 LPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPG 535



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/118 (40%), Positives = 51/118 (43%), Gaps = 38/118 (32%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPG-------FP-----------------------GMPGPP 276
           GPPG PG QGPPG  G KG  G       FP                       G  GPP
Sbjct: 138 GPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPP 197

Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PGP G  GP G +        G+ GP G PG PG  G  GE+G  GP G PG  GS
Sbjct: 198 GPPGPPGPRGPPGDT--------GKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGS 247



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/101 (47%), Positives = 50/101 (49%), Gaps = 16/101 (15%)

Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMP--------GPPGQPGPRGSMGPMGPSPDL 294
           PG  G  GG G PG PG    KG  G  GMP        GPPG PGP G  GPMGP    
Sbjct: 490 PGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP---- 545

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
            H   G +G  GP G  G  G KGERG  G  G PGP G +
Sbjct: 546 -HGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 42/106 (39%), Positives = 50/106 (47%), Gaps = 18/106 (16%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-------- 297
           PG PG+ G +G PG PG  G  G PG  G PG+ G +G  G  GP  D            
Sbjct: 251 PGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAA 310

Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                     + G++G  G PG PG  G KGE G  GP+G PG PG
Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPG 356



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 42/87 (48%), Positives = 48/87 (55%), Gaps = 7/87 (8%)

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRRGPVGP 307
           G+ G  G  G PG KG PG PG+PG PG  G  G +GP G    P L   K G RG  GP
Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTK-GERGEAGP 369

Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PG     G +GE GAPGP+G  G  G+
Sbjct: 370 PGR----GERGEPGAPGPKGKQGESGT 392



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 42/87 (48%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG PG  GPPG  GP G PG  G  GP G  GP G  G  G    +   + G RGP G
Sbjct: 529 GPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG--EPGPRGPYG 586

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
               PG+DG  G  G PGPRG  G  G
Sbjct: 587 L---PGKDGEPGLDGFPGPRGEKGDLG 610



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 42/95 (44%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 247 GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           GPPG  G  G PG PG    KG PG PG  G  G PGP+G  G  G   D    + G +G
Sbjct: 240 GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAG--ENGPKG 297

Query: 304 PVGPPGAPGRD-----GSKGERGAPGPRGSPGPPG 333
             G  G PG       G  GE G PG +G PG PG
Sbjct: 298 DTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPG 332



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 44/100 (44%), Positives = 47/100 (47%), Gaps = 14/100 (14%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG------------QPGPRGSMGPMGPSPD 293
           PGP G PG  GP G PGPKG+ G  G  GP G            +PGPRG  G   P  D
Sbjct: 534 PGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGL--PGKD 591

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 G  GP G  G  G  G KG RG  G +G PG PG
Sbjct: 592 GEPGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPG 631



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 42/100 (42%), Positives = 47/100 (47%), Gaps = 21/100 (21%)

Query: 246 PGPPGLPGGQG---------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPD 293
           PG PG+ G QG          PG  G KG  G PG+PG  G  G +G     GP GPS  
Sbjct: 469 PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPS-- 526

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                    GP GPPG  G  G  G  G PGP+G+ GP G
Sbjct: 527 -------IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMG 559



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 76/165 (46%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------------PGQPGPRG---- 283
           LPG PGLPG +G PG  GP+G PG PG+PG                  PG PGP+G    
Sbjct: 330 LPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGE 389

Query: 284 --------------------SMGPMGP---------------SPDLSHIKQ--------G 300
                               + GP GP               + +L    Q        G
Sbjct: 390 SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449

Query: 301 RRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP GP            PG PG DG +G +G+ G  G PG  G
Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG 494



 Score = 59.3 bits (142), Expect = 6e-09
 Identities = 37/88 (42%), Positives = 41/88 (46%), Gaps = 15/88 (17%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G PG +GP G PG  G PG  G PGP G+ G  G  G  G         +G +G  G
Sbjct: 574 GAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKG--------FRGVKGEKG 625

Query: 307 PPGAPGRDGSKGERGAP---GPRGSPGP 331
            PG PG DG      AP   GP G P P
Sbjct: 626 EPGQPGLDG----LDAPCQLGPDGLPMP 649



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 23/51 (45%), Positives = 25/51 (49%), Gaps = 3/51 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPD 293
           PG  G PG +G  G  G KG  GF G+ G    PGQPG  G   P    PD
Sbjct: 594 PGLDGFPGPRGEKGDLGEKGEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPD 644



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%)

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P G PG+ G +G RG  GP   PG PG
Sbjct: 121 PAGPPGKRGKRGRRGESGP---PGQPG 144


>gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]
          Length = 642

 Score =  101 bits (251), Expect = 1e-21
 Identities = 46/88 (52%), Positives = 55/88 (62%), Gaps = 8/88 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG +GPPG  G  G  G PG+PG PG+PG +G MGP+GP         G++G +
Sbjct: 197 PGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGP--------PGQKGSI 248

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG +G KGE G PG  G  G PG
Sbjct: 249 GAPGIPGMNGQKGEPGLPGAVGQNGIPG 276



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 12/118 (10%)

Query: 228 DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGP 281
           D G    G K     +  PG  G PG  G PG PG KG PGF      PG+PG PG  G 
Sbjct: 304 DPGSSAAGIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGE 363

Query: 282 RGSMGPMG------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           RG  GP G      P       KQG  G  GP G+ G  G KG+ GA GPRG PG  G
Sbjct: 364 RGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKG 421



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 53/117 (45%), Positives = 64/117 (54%), Gaps = 12/117 (10%)

Query: 222 LPNNAADLGKY-ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG 280
           L  +  D+G   +TG+K       LPG  G+ G +G  G PGP+G P   G PGPPG  G
Sbjct: 480 LKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQG-PSIIGPPGPPGPHG 538

Query: 281 PRGSMGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
           P G MGP G P P      +G  GP+GP G  G  G +GE+GA   PGPRG  G PG
Sbjct: 539 PPGPMGPHGLPGP------KGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 16/103 (15%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH---------I 297
           GPPG  G +G  G  GP G PG  G PGP G  G +G  GP    P ++H         I
Sbjct: 123 GPPGKRGKRGRRGESGPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLI 182

Query: 298 K-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           K       QG+ GP GPPG PG  G  G+ G  GPRG PG PG
Sbjct: 183 KRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPG 225



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 46/93 (49%), Positives = 50/93 (53%), Gaps = 5/93 (5%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMGPSPDLSHI-KQG 300
           +PGP G P   GPPG PGP G PG  G   +PGP G  GP G  GP GP  +       G
Sbjct: 519 MPGPQG-PSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMG 577

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP GP G PG+DG  G  G PGPRG  G  G
Sbjct: 578 EPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLG 610



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 16/95 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG PG QG  G  G +GSPG PGM G  G  G +G MG  G +        G +G +G
Sbjct: 449 GPPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMT--------GEKGGIG 500

Query: 307 PPGAPGRDGSKGER---GAPGPR-----GSPGPPG 333
            PG PG +G KGE+   G PGP+     G PGPPG
Sbjct: 501 LPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPG 535



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/118 (40%), Positives = 51/118 (43%), Gaps = 38/118 (32%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPG-------FP-----------------------GMPGPP 276
           GPPG PG QGPPG  G KG  G       FP                       G  GPP
Sbjct: 138 GPPGQPGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSADQQLIKRRLIKGDQGQAGPP 197

Query: 277 GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PGP G  GP G +        G+ GP G PG PG  G  GE+G  GP G PG  GS
Sbjct: 198 GPPGPPGPRGPPGDT--------GKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGS 247



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/101 (47%), Positives = 50/101 (49%), Gaps = 16/101 (15%)

Query: 246 PGPPGLPGGQGPPGSPGP---KGSPGFPGMP--------GPPGQPGPRGSMGPMGPSPDL 294
           PG  G  GG G PG PG    KG  G  GMP        GPPG PGP G  GPMGP    
Sbjct: 490 PGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP---- 545

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
            H   G +G  GP G  G  G KGERG  G  G PGP G +
Sbjct: 546 -HGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPY 585



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 42/106 (39%), Positives = 50/106 (47%), Gaps = 18/106 (16%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-------- 297
           PG PG+ G +G PG PG  G  G PG  G PG+ G +G  G  GP  D            
Sbjct: 251 PGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAA 310

Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                     + G++G  G PG PG  G KGE G  GP+G PG PG
Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPG 356



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 42/87 (48%), Positives = 48/87 (55%), Gaps = 7/87 (8%)

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSHIKQGRRGPVGP 307
           G+ G  G  G PG KG PG PG+PG PG  G  G +GP G    P L   K G RG  GP
Sbjct: 311 GIKGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTK-GERGEAGP 369

Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PG     G +GE GAPGP+G  G  G+
Sbjct: 370 PGR----GERGEPGAPGPKGKQGESGT 392



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 42/95 (44%), Positives = 46/95 (48%), Gaps = 10/95 (10%)

Query: 247 GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           GPPG  G  G PG PG    KG PG PG  G  G PGP+G  G  G   D    + G +G
Sbjct: 240 GPPGQKGSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAG--ENGPKG 297

Query: 304 PVGPPGAPGRD-----GSKGERGAPGPRGSPGPPG 333
             G  G PG       G  GE G PG +G PG PG
Sbjct: 298 DTGEKGDPGSSAAGIKGEPGESGRPGQKGEPGLPG 332



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 42/100 (42%), Positives = 47/100 (47%), Gaps = 21/100 (21%)

Query: 246 PGPPGLPGGQG---------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPD 293
           PG PG+ G QG          PG  G KG  G PG+PG  G  G +G     GP GPS  
Sbjct: 469 PGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKGEKGDSGMPGPQGPS-- 526

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                    GP GPPG  G  G  G  G PGP+G+ GP G
Sbjct: 527 -------IIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMG 559



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 50/165 (30%), Positives = 60/165 (36%), Gaps = 76/165 (46%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----------------PGQPGPRG---- 283
           LPG PGLPG +G PG  GP+G PG PG+PG                  PG PGP+G    
Sbjct: 330 LPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERGEPGAPGPKGKQGE 389

Query: 284 --------------------SMGPMGP---------------SPDLSHIKQ--------G 300
                               + GP GP               + +L    Q        G
Sbjct: 390 SGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTG 449

Query: 301 RRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP GP            PG PG DG +G +G+ G  G PG  G
Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTG 494



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 22/46 (47%), Positives = 24/46 (52%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           G  G PG +GP G PG  G PG  G PGP G+ G  G  G    SP
Sbjct: 574 GAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKVTSP 619



 Score = 32.0 bits (71), Expect = 1.0
 Identities = 14/27 (51%), Positives = 16/27 (59%), Gaps = 3/27 (11%)

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P G PG+ G +G RG  GP   PG PG
Sbjct: 121 PAGPPGKRGKRGRRGESGP---PGQPG 144


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 56/125 (44%), Positives = 65/125 (52%), Gaps = 15/125 (12%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
           P    D G    G + LA +    GP G+PG +G  G+ GP G+ GFPG  G  G PGP 
Sbjct: 866 PGQKGDAGS--PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA 923

Query: 283 GSMGPMGP--------SPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP 329
           G+ GP GP         P L     SH + G RGP GPPG PG  G  GE G PGP G P
Sbjct: 924 GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPP 983

Query: 330 GPPGS 334
           GP G+
Sbjct: 984 GPAGT 988



 Score = 99.4 bits (246), Expect = 5e-21
 Identities = 51/103 (49%), Positives = 57/103 (55%), Gaps = 20/103 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGS---------------PGFPGMPGPPGQPGPRGSMGPMGP 290
           PG  G PG  GPPGSPGP+GS               PGF G  GP G+PGP G  GP+GP
Sbjct: 437 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP 496

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             +     +G+RGP G PG  G  G  GERGAPG RG PG  G
Sbjct: 497 PGE-----EGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 52/106 (49%), Positives = 57/106 (53%), Gaps = 14/106 (13%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G++    +  LPGP G  G +GP GS GPKGS G PG PG PG PG RG  G  G     
Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG----- 579

Query: 295 SHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPGS 334
               QG  G +GP GAPG D      GS G RG PG  G PGP GS
Sbjct: 580 ---VQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 50/107 (46%), Positives = 56/107 (52%), Gaps = 19/107 (17%)

Query: 246  PGPPGLPGGQGPPGSPGP---------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL-S 295
            PGP GLPG QG PG+PGP         +G PG  G  GPPG+ G RG  GP GP  D   
Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD 1132

Query: 296  HIKQGRRGPVGP---------PGAPGRDGSKGERGAPGPRGSPGPPG 333
            H  +G RG  G          PG PG +G +G  G PGP G  GPPG
Sbjct: 1133 HGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG 1179



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 48/91 (52%), Positives = 50/91 (54%), Gaps = 8/91 (8%)

Query: 246 PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PGP   PGLPG  G  G+PG KG  G PG  GPPG  GP GS GP G     S   QG R
Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQG-----STGPQGIR 464

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G PG PG  G  G +G PGP G  GP G
Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIG 495



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 1/88 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPV 305
           G  G  G QGP G PG KG PG PG  G  G PGP+G  G  GP  P+     +G RG  
Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPGA G  GS G  G PGP G+PGP G
Sbjct: 903 GPPGATGFPGSAGRVGPPGPAGAPGPAG 930



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 49/97 (50%), Positives = 53/97 (54%), Gaps = 11/97 (11%)

Query: 247 GPPGLPGGQGPPGSPGPKG------SPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
           G PG  G  G PG PGP G      S GFPG PG  G+ GP G+ GP GP       + G
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG--ETG 408

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSP---GPPGS 334
             GPVG PG PG  G+ G  GA GP GSP   GPPGS
Sbjct: 409 PPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS 445



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 51/108 (47%), Positives = 54/108 (50%), Gaps = 19/108 (17%)

Query: 246 PGPPGLPGGQ---------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           PG  GLPG +         GP GSPGP G+PG  G PG  G PG RG  G  GP  D   
Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG 781

Query: 297 I----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           I            G RG  GP G PG  G  GE+G PGPRG  GPPGS
Sbjct: 782 IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 46/92 (50%), Positives = 52/92 (56%), Gaps = 5/92 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PGL G +G  G  GPKG  G PG  G  G  GP G+MGP+GP         G RG +
Sbjct: 293 PGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRG-----MPGERGRL 347

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           GP GAPG+ G+ G  G PGP G  G PGS  F
Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGF 379



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 47/87 (54%), Positives = 51/87 (58%), Gaps = 8/87 (9%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G  G  G QG PG PGP G  G  G+PGP    GPRG  GP+GPS      K+G  GP+G
Sbjct: 1143 GHRGFTGLQGLPGPPGPNGEQGSAGIPGP---FGPRGPPGPVGPSG-----KEGNPGPLG 1194

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P G PG  GS GE G  GP G PGPPG
Sbjct: 1195 PIGPPGVRGSVGEAGPEGPPGEPGPPG 1221



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 52/134 (38%), Positives = 57/134 (42%), Gaps = 46/134 (34%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSP---------GFPGMPGPPGQPGP--------------- 281
           PGP G PG QGP G  GPKG P         G PG+PG PG PGP               
Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190

Query: 282 ---------------------RGSMGPMGP-SPDLSHIKQGRRGPVGPPGAPGRDGSKGE 319
                                 GS+GP+GP  P     +QG  GP GPPG PG  G  G 
Sbjct: 191 FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGP 250

Query: 320 RGAPGPRGSPGPPG 333
            G+ GP G PG PG
Sbjct: 251 IGSRGPEGPPGKPG 264



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 51/124 (41%), Positives = 65/124 (52%), Gaps = 12/124 (9%)

Query: 215 LKQKIALLPNNAADLG----KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP 270
           L  ++ L+P +   +G    + + G +  A  T  PG PG PG  GP GS GP+G PG P
Sbjct: 204 LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKP 263

Query: 271 GMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
           G  G PG+ G  G +G  G SP       G RG  G PG PG  G +G +G  GP+G  G
Sbjct: 264 GEDGEPGRNGNPGEVGFAG-SP-------GARGFPGAPGLPGLKGHRGHKGLEGPKGEVG 315

Query: 331 PPGS 334
            PGS
Sbjct: 316 APGS 319



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 47/101 (46%), Positives = 52/101 (51%), Gaps = 13/101 (12%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP----SPDLSHIKQGR- 301
           GP G PG  GPPG  G +G+PG  G PG  G PGP+G+ G  GP     P  S    GR 
Sbjct: 504 GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRP 563

Query: 302 --------RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                   RG  G PG  G +G  G  GAPG  G PGPPGS
Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 5/100 (5%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G   LA      GPPG  G QG PG PGP G  G PG  G PG PG  G +GP G   + 
Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGN- 715

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                G RG  G  G PG  G  G  G  GP+GSPGP G+
Sbjct: 716 ----PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 44/102 (43%), Positives = 55/102 (53%), Gaps = 13/102 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP---------GPRGSMGPMGPSPDLSH 296
            PGP G  G +G  G PG +G  G PG+PGP G P         G +G  GP+GP      
Sbjct: 983  PGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042

Query: 297  I-KQGRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPGS 334
            + + G  GP G  G PGRDG+   +G+RG PGP G PG  G+
Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 51/116 (43%), Positives = 55/116 (47%), Gaps = 15/116 (12%)

Query: 222  LPNNAADLGKY----ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277
            LP  A   GK      TGDK        PGP G PG  GP G PGP+G  G  G PG  G
Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGP------PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 278  QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G RG  G  GP+        G +G  G PG  G  G  G+RG PG RG  GPPG
Sbjct: 1063 AVGERGDRGDPGPAG-----LPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPG 1113



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 53/116 (45%), Positives = 55/116 (47%), Gaps = 26/116 (22%)

Query: 246 PGPPGLPGG---------QGPPGSPGPKGSPGFPGMPGPPG------QPGPRGSMGPMGP 290
           PG PGLPG          QGP G  GP G+PG  G PGPPG      QPG  G  GP G 
Sbjct: 563 PGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGS 622

Query: 291 SPDLSHIKQGRRGPVGPPG---APGRDGSKGERGAPGP------RGSPGPPGSFDF 337
           S D    K G  G  G PG   APG+DG  G  G  GP      RG  GPPG   F
Sbjct: 623 SGDPG--KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGF 676



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 45/103 (43%), Positives = 49/103 (47%), Gaps = 16/103 (15%)

Query: 247  GPPGLPGGQG------------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----P 290
            GPPGL G  G            PPG PG KG PG  G PGP G PGP G+ G  G    P
Sbjct: 939  GPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP 998

Query: 291  SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                     G  GP G PG  G  G+ G++G PGP G PG  G
Sbjct: 999  GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 42/87 (48%), Positives = 45/87 (51%), Gaps = 8/87 (9%)

Query: 251 LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA 310
           +PG  GP G  GP+G  G  G  GP G PG  G  GPMGP         G RGP GPPG 
Sbjct: 211 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPI--------GSRGPEGPPGK 262

Query: 311 PGRDGSKGERGAPGPRGSPGPPGSFDF 337
           PG DG  G  G PG  G  G PG+  F
Sbjct: 263 PGEDGEPGRNGNPGEVGFAGSPGARGF 289



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/93 (47%), Positives = 51/93 (54%), Gaps = 4/93 (4%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS--HIKQGR 301
           PG  GLPG +G  G PG  G  G  G+PG  G PG  G +GP GP   P L+    +QG 
Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP 670

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            GP G  G PG  G  GE G PG +G PG PG+
Sbjct: 671 PGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGA 703



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 43/94 (45%), Positives = 49/94 (52%), Gaps = 11/94 (11%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQ 299
            PG  G PG  GPPG  G  G  G  GMPG       PG PGP G+ G +GP+        
Sbjct: 971  PGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG-----AT 1025

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +GP GP G PG +G  GE G  GP G+ G PG
Sbjct: 1026 GDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPG 1059



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 48/117 (41%), Positives = 51/117 (43%), Gaps = 11/117 (9%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GD+    +    G  GLPG  GP G  G  G PG  G  GPPG  GP G  G  GP    
Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGP---- 1192

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITE 351
                    GP+GPPG  G  G  G  G PG  G PGPPG    L   L DI     E
Sbjct: 1193 -------LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDE 1242



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 47/97 (48%), Positives = 54/97 (55%), Gaps = 7/97 (7%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQG 300
            LPGP G PG  GP G+ G KG PG    PG  GP G+PGP G  G  G P  D +  ++G
Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068

Query: 301  RRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPGS 334
             RG  GP   PG+ G  G+ G  GAPG  G  G PGS
Sbjct: 1069 DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 1/95 (1%)

Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIK 298
           A N  +PG  G PG  G  G  GP G PG  G  G  G PGP G  G P  P P     K
Sbjct: 632 AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +G  G PGA G  G +GERG PG RG PG  G
Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITG 726



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 46/104 (44%), Positives = 54/104 (51%), Gaps = 4/104 (3%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSP 292
           TG + +      PG PG  G  GP G PGP G  G  G PG  G+ GPRG  G +G P P
Sbjct: 458 TGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGP 517

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333
                  G RG  G  G PG  G++GER   G+ GP+GS G PG
Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 47/117 (40%), Positives = 56/117 (47%), Gaps = 16/117 (13%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRGSMGPMG 289
           + G + L  N  + GP G  G  G PG  G  G P   G  G PG  G PGP+GS G  G
Sbjct: 568 LPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPG 627

Query: 290 PSPDLSHI----------KQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSPGPPG 333
              +  +           K G  GP GP G PG  G +GE+G PGP   +G PGPPG
Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 53/121 (43%), Positives = 55/121 (45%), Gaps = 16/121 (13%)

Query: 219 IALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGP 275
           IA  P    D G    G+K         G  GLPG  GPPG  GP   KG PG  G+ GP
Sbjct: 769 IAGTPGPKGDRGGI--GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826

Query: 276 PGQ---PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332
           PG    PG RG  GP G          G  GP GP G PG  G  GE G  G  GSPGP 
Sbjct: 827 PGSRGNPGSRGENGPTG--------AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQ 878

Query: 333 G 333
           G
Sbjct: 879 G 879



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/118 (40%), Positives = 54/118 (45%), Gaps = 38/118 (32%)

Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFPGMPG---------------------------P 275
           PGPPG  G +G PGS   PGPKGS G PG PG                           P
Sbjct: 599 PGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658

Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG  G RG  GP GP+        G +G  GPPG PG  G  G++G PG  G+ GP G
Sbjct: 659 PGLAGERGEQGPPGPT--------GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 45/98 (45%), Positives = 54/98 (55%), Gaps = 13/98 (13%)

Query: 247 GPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299
           GP G  G  GP G PG      P+G+PG  G  G PG+PGP   MGP+G P         
Sbjct: 327 GPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGP---MGPLGIPGSSGFPGNP 383

Query: 300 GRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPGS 334
           G +G  GP GA G +G +G+R   G PGP GSPG PG+
Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 47/132 (35%), Positives = 55/132 (41%), Gaps = 43/132 (32%)

Query: 245 LPGPPGLPGGQGPPG---------------------SPGPKGSPGFPGMPGPPGQPG--- 280
           LPGPPG PG  G PG                     +PG +G PG  G+PG  G  G   
Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG 738

Query: 281 ---PRGSMGPMGPSPDL----------------SHIKQGRRGPVGPPGAPGRDGSKGERG 321
              P+GS GP G   D                 +   +G RG +G  GA G  G+ G RG
Sbjct: 739 PDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARG 798

Query: 322 APGPRGSPGPPG 333
            PGP G PGP G
Sbjct: 799 LPGPLGPPGPAG 810



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 38/86 (44%), Positives = 42/86 (48%), Gaps = 12/86 (13%)

Query: 252 PGGQGPPGSPGPKGSPGFPGM----PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307
           PGG       G KG  G PG+     G  G+PGP G  G  GP        +G RGP G 
Sbjct: 100 PGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGP--------RGERGPKGR 151

Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG  G  G  GE G PG  G+PGPPG
Sbjct: 152 PGPRGPQGIDGEPGVPGQPGAPGPPG 177



 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 47/131 (35%), Positives = 51/131 (38%), Gaps = 44/131 (33%)

Query: 247 GPPGL----PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---------------- 286
           G PGL     G +G PG  GP GS G  G  GP G+PGPRG  G                
Sbjct: 116 GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGP 175

Query: 287 ---PMGPSPD-LSH--------------------IKQGRRGPVGPPGAPGRDGSKGERGA 322
              P  P PD LS                     +  G  GPVGP G  G  G +G  G 
Sbjct: 176 PGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP 235

Query: 323 PGPRGSPGPPG 333
            GP G PG PG
Sbjct: 236 TGPPGEPGDPG 246


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 49/91 (53%), Positives = 49/91 (53%), Gaps = 8/91 (8%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  GLPG  GPPG PGP G  GFPG  G  GQ GP G  GP GP         G  GP 
Sbjct: 1291 PGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP--------HGFPGPP 1342

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
            G  G PG  G KG  G PGPRG PGPP   D
Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373



 Score = 98.2 bits (243), Expect = 1e-20
 Identities = 52/104 (50%), Positives = 59/104 (56%), Gaps = 13/104 (12%)

Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD-----L 294
           PGPPGLPG QG       PG  G KG PG PG  GPPG PG  G+ GP G         +
Sbjct: 502 PGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVV 561

Query: 295 SHIK--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
           S +K  +G RGP GPPG PG+ GS G  G  G +G PGPPG  +
Sbjct: 562 SRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHE 605



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 49/111 (44%), Positives = 59/111 (53%), Gaps = 21/111 (18%)

Query: 245 LPG-PPGLPGGQGPPGSPGPKGSPGFPGMPGPP------GQPGPRGSMGPMGP------- 290
           +PG P   PG  G PGSPG  G+PG  G+PG        G PGP+G  G +GP       
Sbjct: 424 IPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPK 483

Query: 291 ----SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP---GPRGSPGPPGS 334
               +  L   + G  GP GPPG PGR GSKG+ G P   G +G PGPPG+
Sbjct: 484 GEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGA 534



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 53/117 (45%), Positives = 57/117 (48%), Gaps = 29/117 (24%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-----------PSPDL 294
            PG PG PG  GPPG PG  G PG  G PG  G PGPRG  G  G            SP L
Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGL 1176

Query: 295  S--HIKQGRRG--------PVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333
            +  H  +G++G         VGPPG  G  G KGERG         PGPRG  GPPG
Sbjct: 1177 NGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPG 1233



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 46/94 (48%), Positives = 52/94 (55%), Gaps = 9/94 (9%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIKQ 299
           +PGPPG    +G PG PG  G PG+PG PG PG  G  G +GP GP+     P L     
Sbjct: 820 VPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGL----P 875

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GR G  GPPG PG  G  G+ G PGP G  GP G
Sbjct: 876 GRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRG 909



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 50/106 (47%), Positives = 50/106 (47%), Gaps = 19/106 (17%)

Query: 247  GPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-----K 298
            GP G PG QGP   PG PG KG PG PG  GP G PGPRG  GP     D   I      
Sbjct: 1325 GPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGA 1384

Query: 299  QGRRGPVGP-----------PGAPGRDGSKGERGAPGPRGSPGPPG 333
             G RGP G            PG  G  G  G RG  G  GSPGPPG
Sbjct: 1385 PGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPG 1430



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 50/105 (47%), Positives = 54/105 (51%), Gaps = 17/105 (16%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSPD 293
            PG  G PG  GPPG PG  G  GF            PG PGPPG  G  G+ GP G   D
Sbjct: 1017 PGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGD 1076

Query: 294  -LSHI-KQGRRGPVGPPGAPGRDGSKGERGAP---GPRGSPGPPG 333
              SH    G +G  G PG PG  G+ GE+G P   GPRGSPG PG
Sbjct: 1077 PASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPG 1121



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 44/98 (44%), Positives = 56/98 (57%), Gaps = 7/98 (7%)

Query: 245  LPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI---- 297
            LPG PG PG +G PG+   PG KG PG  GM G PG  G RG+ G +GP  D   +    
Sbjct: 910  LPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIIS 969

Query: 298  KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
            ++G  G  GPPG  G  G +G++G PG +G  G PG +
Sbjct: 970  QKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 52/114 (45%), Positives = 56/114 (49%), Gaps = 27/114 (23%)

Query: 247  GPPGLPGGQGPPGSPGPKG-------SPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHI 297
            GPPG PG  GPPG  G  G        PG PG  GPPG  GPRG+ GP G   S DL   
Sbjct: 1230 GPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRG 1289

Query: 298  KQGRRGPVGPPGAP---------------GRDGSKGERGAPGPRGS---PGPPG 333
            + G  G  GPPG P               G+DG KG  G PGP+G    PGPPG
Sbjct: 1290 EPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPG 1343



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 48/98 (48%), Positives = 53/98 (54%), Gaps = 5/98 (5%)

Query: 240  ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296
            AS+   PGP G PG  G PG  G  G  G PG+ GP   PG+PGP GS GP G   D  H
Sbjct: 1078 ASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGD--H 1135

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               G RG  G  G PG  G +G+ G PGP G  GP GS
Sbjct: 1136 GMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGS 1173



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 49/113 (43%), Positives = 55/113 (48%), Gaps = 22/113 (19%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPG----------FPGMPGPPGQPGPRGSMG------PMGP 290
            G PG PG +GP G PGP+G PG           PG+PG PG  GP G+MG      P GP
Sbjct: 1346 GLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGP 1405

Query: 291  SPDLSHIKQGRRGPVGPPGAPGRDGSKGERG------APGPRGSPGPPGSFDF 337
                     GRRG  G PG+PG  G KG+ G       PGP G  G PG   F
Sbjct: 1406 GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGF 1458



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/114 (42%), Positives = 53/114 (46%), Gaps = 15/114 (13%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GDK     T +PG PGL G  G PG PGP+G PG  G  G  G PG  G  G +GP   L
Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163

Query: 295 SH---------------IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            H                 +G +G  G PG PG  GS G  G  GP G PG PG
Sbjct: 164 GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPG 217



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 1/90 (1%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRG 303
           LPG PG PG  GPPG PG  G  G  G+PGPPG  GPRG  G P  P        +G  G
Sbjct: 871 LPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPG 930

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG  G  G  G+RG  G +G+ GPPG
Sbjct: 931 AKGEPGEKGMSGLPGDRGLRGAKGAIGPPG 960



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/104 (45%), Positives = 52/104 (50%), Gaps = 17/104 (16%)

Query: 247 GPPGLPGGQGPPGS--PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           GPPG  G  GPPG   PGP G  G PG+PG PG  GP G  G  G +   +    GR GP
Sbjct: 619 GPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGP 678

Query: 305 ------------VGPPGAPGRDGSKGERGAPGPRGS---PGPPG 333
                        GP GAPG  GS G +G PG  G+   PGPPG
Sbjct: 679 PGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 42/84 (50%), Positives = 48/84 (57%), Gaps = 8/84 (9%)

Query: 253 GGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309
           G +GPPG PGP+G  G  G PGP    G+ G RG  GP G + D     +G +GP G PG
Sbjct: 62  GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGD-----KGDKGPTGVPG 116

Query: 310 APGRDGSKGERGAPGPRGSPGPPG 333
            PG DG  G  G PGPRG PG  G
Sbjct: 117 FPGLDGIPGHPGPPGPRGKPGMSG 140



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 50/132 (37%), Positives = 62/132 (46%), Gaps = 33/132 (25%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPP----GQPGPRGS 284
            G+  + S    PG PG PG  G PG  G KG+PG       PG  GPP    G+PG +G 
Sbjct: 963  GEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQ 1022

Query: 285  MGPMGP--SPDLSHIK-----------QGRRGPVGPPGAPGRDGSKGER----------G 321
             GP GP   P  + ++           QG  G  GPPG  G DG++G +          G
Sbjct: 1023 PGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFG 1082

Query: 322  APGPRGSPGPPG 333
             PGP+G PG PG
Sbjct: 1083 PPGPKGEPGSPG 1094



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 53/124 (42%), Positives = 61/124 (49%), Gaps = 19/124 (15%)

Query: 226  AADLGKYITGDKVLASNTYLPGPPGLPG-----------GQ-GPPGSPGPKGSPGFP--- 270
            + DL +   GD  L      PGPPG PG           GQ GP G PGP+G  GFP   
Sbjct: 1283 SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPP 1342

Query: 271  ---GMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
               G+PGPPG+ GP G  GP G     + +    R P G PGAPG  G +G  G PG RG
Sbjct: 1343 GEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIP-GLPGAPGMRGPEGAMGLPGMRG 1401

Query: 328  SPGP 331
              GP
Sbjct: 1402 PSGP 1405



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 11/87 (12%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG  G  G PG  GP+G PG PG  GP G PG  G  GP           +GR G  G
Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGP-----------KGREGHAG 816

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG PG  G   ERGAPG  G PG PG
Sbjct: 817 FPGVPGPPGHSCERGAPGIPGQPGLPG 843



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 51/137 (37%), Positives = 57/137 (41%), Gaps = 46/137 (33%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPP-----------------------GSPGPKGSPGFPG 271
            G + L  +  +PGPPG+ G  G P                       G PGP G PG  G
Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210

Query: 272  MPGPPGQ-----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA----------PGRDGS 316
              G PG      PGPRG  GP GP         G  GP GP GA          PG  G 
Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGP--------PGSSGPPGPAGATGRAPKDIPDPGPPGD 1262

Query: 317  KGERGAPGPRGSPGPPG 333
            +G  G  GPRG+PGPPG
Sbjct: 1263 QGPPGPDGPRGAPGPPG 1279



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 50/114 (43%), Positives = 57/114 (50%), Gaps = 20/114 (17%)

Query: 235 GDKVLASNTY--LPGPPGLPGGQGPPGSPGPKGSPGF---------PGMPGPPGQPGPRG 283
           GD +  + TY    GPPG  G  GP G PGP+G+PG          PG PG    PGP G
Sbjct: 663 GDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPG 722

Query: 284 SMGPMGPSPDLSHIKQGRRG--PVGPPGAPGRDGSKGERGAPGPR--GSPGPPG 333
             G MG  P       G +G  PVGPPG PG  G  G++G PG    G  GPPG
Sbjct: 723 FRGDMG-DPGFG----GEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPG 771



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 46/101 (45%), Positives = 51/101 (50%), Gaps = 15/101 (14%)

Query: 246  PGPPG---LPGGQGPPGS----------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            PGPPG   + G +GP G+          PGPKG PG PG PG  G  G +G  G  GP  
Sbjct: 1056 PGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRG 1115

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              S  + G  G  GPPG PG  G  G RG PG  G PGP G
Sbjct: 1116 --SPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG 1154



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/95 (47%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHI--K 298
           PGPPG  G  GP G+PGP G  G  GM G  G PG  G  G  GP+     P L  I   
Sbjct: 67  PGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGH 126

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GP G PG  G +GS+G+ G PG RG+ GP G
Sbjct: 127 PGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGG 161



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 49/108 (45%), Positives = 55/108 (50%), Gaps = 22/108 (20%)

Query: 245  LPGPPGLPGGQGPPG----SPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
            + G  G PG  GPPG     PG KG PG PG PGPPG  G RG +G  G   D     QG
Sbjct: 997  MQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD-----QG 1051

Query: 301  RRGPVGPPGAPGRDGSKGERG----------APGPRG---SPGPPGSF 335
              G  GPPG  G DG++G +G           PGP+G   SPG PG F
Sbjct: 1052 EPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHF 1099



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 52/130 (40%), Positives = 58/130 (44%), Gaps = 36/130 (27%)

Query: 235 GDKVLASNTYLPGPPG--------------LPGGQGPPGSPGPKGSPGFPGMP------- 273
           G K +     LPGPPG              +PG  GP G PG  GSPGFPG+        
Sbjct: 273 GIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVG 332

Query: 274 --------GPPGQPGPRGSMGPMG--PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAP 323
                   GP G PG RG  GP G   +P L       +GP G PG PGR G  G+ G P
Sbjct: 333 DPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP-----LKGPPGDPGFPGRYGETGDVGPP 387

Query: 324 GPRGSPGPPG 333
           GP G  G PG
Sbjct: 388 GPPGLLGRPG 397



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 63/192 (32%), Positives = 71/192 (36%), Gaps = 59/192 (30%)

Query: 247 GPPGLPG---GQGPPGSPG------------------PKGSPGFPGM------------- 272
           GPPGLPG     GPPG+ G                  P G PGFPG              
Sbjct: 536 GPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEK 595

Query: 273 --PGPPGQ-----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA--PGRDGSKGERGAP 323
             PGPPG      PG +G  GP+GP         G+ GPVGPPG   PG  G +G  G P
Sbjct: 596 GDPGPPGDHEDATPGGKGFPGPLGP--------PGKAGPVGPPGLGFPGPPGERGHPGVP 647

Query: 324 GPRGSPGPPGSFDFLLLMLADIRNDITELQEKVFGHRTHSSAEEFPLPQEFPSYPEAMDL 383
           G  G  GP G        L   + D         G       +  P P+ FP    A  L
Sbjct: 648 GHPGVRGPDG--------LKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699

Query: 384 GSGDDHPRRTET 395
              D H  R  T
Sbjct: 700 SGSDGHKGRPGT 711



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 42/100 (42%), Positives = 53/100 (53%), Gaps = 10/100 (10%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD--LSHIK---- 298
           +PGP G  G  GPPG  GP+G PGFPG PG  G+PG  G  G  G   +  +S +     
Sbjct: 889 IPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRG 948

Query: 299 -QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            +G +G +GPPG  G      ++G PG    PGPPG   F
Sbjct: 949 LRGAKGAIGPPGDEGEMAIISQKGTPG---EPGPPGDDGF 985



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 46/97 (47%), Positives = 51/97 (52%), Gaps = 9/97 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG-----SMGPMGPSPDLSHI-KQ 299
           PG PGLPG  G  G  GP G PG PG+ GPPGQPG  G      +G  G   D   + +Q
Sbjct: 192 PGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQ 251

Query: 300 GRRGP---VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GP   V PP      G KG +G PG  G PGPPG
Sbjct: 252 GSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 41/89 (46%), Positives = 45/89 (50%), Gaps = 8/89 (8%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G PG  GPPG    +G+PG PG PG PG PG  G+ G  G   D+        GP G
Sbjct: 813 GHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDV--------GPPG 864

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
           P G  G  G  G  GA GP G PG PG F
Sbjct: 865 PAGMKGLPGLPGRPGAHGPPGLPGIPGPF 893



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 46/110 (41%), Positives = 53/110 (48%), Gaps = 21/110 (19%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGS------PGFPGM---PGPPGQPGPRGSMGPMGPSPDLS 295
           L G  G+ G +GPPG+ G KG       PGFPG+   PG PG PGPRG  G  G +    
Sbjct: 87  LSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRG 146

Query: 296 HI----KQGRRGPVGPPGAPGRDGSKGE--------RGAPGPRGSPGPPG 333
                  +G  GP GP G PG  G KG         +G  G RG PG PG
Sbjct: 147 DPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPG 196



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 44/101 (43%), Positives = 48/101 (47%), Gaps = 15/101 (14%)

Query: 245 LPGPPGLPGGQGPPGSPG-----------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
           L GP G PG +G PG PG           P G PGFPG  G  G  GP G  G +G   +
Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPG-PRGSPGPPG 333
                 G  GP GP G PG  G  GE G PG P  +PG PG
Sbjct: 399 AC---AGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPG 436



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 46/111 (41%), Positives = 54/111 (48%), Gaps = 20/111 (18%)

Query: 235 GDKVLASNTYLPGPPGL---PGGQGPPGSP------GPK---GSPGFPGMPGPPGQPGPR 282
           G + L+    + GP G    PG +GP G P      GPK   G  GFPG+PGPPG    R
Sbjct: 771 GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCER 830

Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G+ G  G        + G  G  G PGAPG  G  G+ G PGP G  G PG
Sbjct: 831 GAPGIPG--------QPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG 873



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 53/148 (35%), Positives = 57/148 (38%), Gaps = 9/148 (6%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           +PGPPG  G  G PG  G KGS       GPPG PG  G  G  G   D +    G  GP
Sbjct: 717 IPGPPGFRGDMGDPGFGGEKGSSPV----GPPGPPGSPGVNGQKGIPGDPAF---GHLGP 769

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQ--EKVFGHRTH 362
            G  G  G  G KG RG PG  G+ GP G   FL L     R             GH   
Sbjct: 770 PGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCE 829

Query: 363 SSAEEFPLPQEFPSYPEAMDLGSGDDHP 390
             A   P     P YP +     G   P
Sbjct: 830 RGAPGIPGQPGLPGYPGSPGAPGGKGQP 857



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 46/119 (38%), Positives = 51/119 (42%), Gaps = 37/119 (31%)

Query: 247 GPPGLPGGQGPP---------------GSPGPKGSPGFPGMPGPPGQ------------- 278
           G PG  G QG P               G  G KG PG  G+PGPPG+             
Sbjct: 243 GDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKG 302

Query: 279 ----PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               PGPRG  G  G SP       G +G +G  G PG  G  G +G PG RG PGPPG
Sbjct: 303 IPGFPGPRGDPGSYG-SPGF----PGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPG 356



 Score = 62.0 bits (149), Expect = 9e-10
 Identities = 49/135 (36%), Positives = 55/135 (40%), Gaps = 37/135 (27%)

Query: 240 ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDL 294
           A  T  PG PGL G  G PG PG KG+PG  G+ G  G PG  G  G  GP+     PD 
Sbjct: 207 AGPTGYPGEPGLVGPPGQPGRPGLKGNPGV-GVKGQMGDPGEVGQQGSPGPTLLVEPPDF 265

Query: 295 SHIK-----QGRRGPVGPPGAPGRDG-----------------------SKGERGAPGPR 326
              K     +G  G VG PG PGR G                       S G  G PG +
Sbjct: 266 CLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLK 325

Query: 327 GS---PGPPGSFDFL 338
           G     G PG F  +
Sbjct: 326 GELGLVGDPGLFGLI 340



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 27/50 (54%), Positives = 27/50 (54%), Gaps = 3/50 (6%)

Query: 246  PGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            PG  G  G  G PGSPGP   KG  G  G PG PG PGP G  GP G  P
Sbjct: 1411 PGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGPKGFGP 1460



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 25/53 (47%), Positives = 30/53 (56%), Gaps = 11/53 (20%)

Query: 282 RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           +GS GP GP         G +GP+GP GAPG  G  GE+G    RG  GPPG+
Sbjct: 61  KGSRGPPGPP--------GPQGPIGPLGAPGPIGLSGEKGM---RGDRGPPGA 102



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 31/91 (34%), Positives = 34/91 (37%), Gaps = 34/91 (37%)

Query: 245  LPGPPGLPGGQGP-----------PGSPGPKGSPGF------------PGMPGPPGQPGP 281
            +PG PG PG +GP           P  PG KG PG             PG PG  G  G 
Sbjct: 1378 IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGE 1437

Query: 282  RGSMGPMGPSPDLSHIKQGRRGPVGPPGAPG 312
             G  G  GP            GP+G PG  G
Sbjct: 1438 DGYPGGPGPP-----------GPIGDPGPKG 1457



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 21/45 (46%), Positives = 24/45 (53%), Gaps = 9/45 (20%)

Query: 298 KQGRRGPVGPP---------GAPGRDGSKGERGAPGPRGSPGPPG 333
           ++G RGP GPP         GAPG  G  GE+G  G RG PG  G
Sbjct: 60  EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 99.0 bits (245), Expect = 7e-21
 Identities = 54/113 (47%), Positives = 62/113 (54%), Gaps = 26/113 (23%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQ------------PGPRGSMGPMG 289
           +PG  GLPG QGPPG PGPKG PG     G PG PGQ            PGP G +GP G
Sbjct: 864 IPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQG 923

Query: 290 PSPDLSHIKQGRRGPVGPPGAP---------GRDGSKGERGAPGPRGSPGPPG 333
            + ++  +  G RGP GPPG P         GR+G+KGE G PGP G  GP G
Sbjct: 924 KTGEVGPL--GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 14/95 (14%)

Query: 246  PGPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PGPPG PG  GP G        GP G+ G PG  GPPG+ G +GS+GP G   DL     
Sbjct: 1213 PGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDL----- 1267

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               GP G PG  G DGS GE+G PG  G PGPPG+
Sbjct: 1268 ---GPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGA 1299



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 46/90 (51%), Positives = 55/90 (61%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---GPMGPSPDLSHIKQGRRG 303
           G  G  G +GPPGS G KG  G PG+PG PG+PGP+GS+   GP+GP  +    K G+ G
Sbjct: 767 GQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG--KSGKTG 824

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  G  GS+GERG PG  G PGP G
Sbjct: 825 QPGLEGERGPPGSRGERGQPGATGQPGPKG 854



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 46/88 (52%), Positives = 52/88 (59%), Gaps = 4/88 (4%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG  G +G PG  GPKG  GF G+PG PG+ G RG  G +G P P     + G RG  
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPP---GEDGERGAE 586

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G+ G  G RG  GPRGSPGP G
Sbjct: 587 GPPGPTGQAGEPGPRGLLGPRGSPGPTG 614



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 48/100 (48%), Positives = 54/100 (54%), Gaps = 14/100 (14%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGP G PG  G  G+PG KG+ G PG PGPPGQ G  GS G  GP   +     G +GP 
Sbjct: 610 PGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG--TPGEKGPP 667

Query: 306 GPPGA------------PGRDGSKGERGAPGPRGSPGPPG 333
           G PG             PG +G  GE+GA GP GS GPPG
Sbjct: 668 GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPG 707



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 14/102 (13%)

Query: 235  GDKVLASNTYLPG---PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
            G K     T LPG   PPG PG  G  GSPG KG PG  G PGPPG  G  G+ GP    
Sbjct: 1253 GAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP---- 1308

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                    G+RGP G  G  GR+G KG +G PGP G PG  G
Sbjct: 1309 -------PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTG 1343



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 4/89 (4%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
            G  GL G  GPPG  G KG  G PG+ GP   PGP+G  GP GP   L H    G  GP+
Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLPGVQGP---PGPKGDPGPPGPIGSLGHPGPPGVAGPL 1459

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G  G+ G  GS G RG  GP G PGPPG+
Sbjct: 1460 GQKGSKGSPGSMGPRGDTGPAGPPGPPGA 1488



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 49/113 (43%), Positives = 55/113 (48%), Gaps = 25/113 (22%)

Query: 246  PGPPGLPGGQG---PPGSPGPKGS------------PGFPGMPGPPGQPGPRGSMGPMGP 290
            PGPPG  G QG   PPG  G KG             PG  G+PGPPG+ G  G +G MGP
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 291  ----------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                       P  S    G  G VG PGA G  G +G+ G PGP G+PG PG
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPG 1223



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 50/122 (40%), Positives = 55/122 (45%), Gaps = 34/122 (27%)

Query: 246  PGPPGLPGGQ------------------GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287
            PGPPG PG Q                  GP G  GP G  GFPG  G PG PGP G  G 
Sbjct: 937  PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996

Query: 288  MG-PSPDLSHIKQGRRGPVGPPGA---------------PGRDGSKGERGAPGPRGSPGP 331
             G P P  ++   G RGP+GP G                 G+ GS+GERG PGP G  G 
Sbjct: 997  KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056

Query: 332  PG 333
            PG
Sbjct: 1057 PG 1058



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 47/100 (47%), Positives = 52/100 (52%), Gaps = 17/100 (17%)

Query: 246 PGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PG PGLPG  GP G P      G KG+ G PG  GPPG PGPRG  G  G     +   Q
Sbjct: 670 PGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSG-----NRGLQ 724

Query: 300 GRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333
           G +G  G  G P      G  G +G+ GAPGPRG  GP G
Sbjct: 725 GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 51/138 (36%), Positives = 66/138 (47%), Gaps = 22/138 (15%)

Query: 218 KIALLPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGS------PGPKGSPGFPG 271
           ++  +    AD  + + GD     +    G PGLPG +G  G       PGP G  G  G
Sbjct: 525 RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584

Query: 272 MPGPP------GQPGPRGSMGPMG-PSP---------DLSHIKQGRRGPVGPPGAPGRDG 315
             GPP      G+PGPRG +GP G P P         D +   +G  GP G PG PG+ G
Sbjct: 585 AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644

Query: 316 SKGERGAPGPRGSPGPPG 333
           + G +G PGP+G  G PG
Sbjct: 645 NHGSQGLPGPQGLIGTPG 662



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 48/112 (42%), Positives = 57/112 (50%), Gaps = 26/112 (23%)

Query: 246  PGPPGLPG------GQGPPGSPGPKGSPGF------PGMPGPPGQPGPRGSMGP------ 287
            PGP G PG       +GPPG  GP+G  G       PG+ G PGQ GP G +GP      
Sbjct: 1333 PGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGL 1392

Query: 288  ---MGPSPDLSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333
                GP  +  HI  G  G +GPPG  G  G +   G +G PGP+G PGPPG
Sbjct: 1393 KGDTGPKGEKGHI--GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 49/118 (41%), Positives = 53/118 (44%), Gaps = 31/118 (26%)

Query: 247 GPPGLPGGQGPPGS------------PGPK------------GSPGFPGMPGPPGQPGPR 282
           G PGL G +GPPGS            PGPK            G  G PG+ GPPG PGP+
Sbjct: 824 GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPK 883

Query: 283 GSMGPMGPSPDLSHIK-------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G  G      H         QG+ GP GP G  G  G  GE G  G RG PGPPG
Sbjct: 884 GPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPG 941



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 43/95 (45%), Positives = 52/95 (54%), Gaps = 7/95 (7%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
            G PG  G +GP G  G KGS G  G PGP G+ G  G +GP+GP        ++G +G V
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081

Query: 306  GPPGAPGRDGSKGERGAP------GPRGSPGPPGS 334
            G PG  G  G KG+ G P      GP G PGPPG+
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGA 1116



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 50/105 (47%), Positives = 52/105 (49%), Gaps = 8/105 (7%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           I G      N   PG PG PG QG  GS   PGP+G  G PG  GPPG PG  G  G  G
Sbjct: 621 IDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG 680

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           P   L H   G  GP G  GA G  GS G  G PGPRG  G  G+
Sbjct: 681 P---LGH--PGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGN 720



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 49/122 (40%), Positives = 55/122 (45%), Gaps = 23/122 (18%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPG---------PKGSPGFPGMPGP--------- 275
           TG+K         GPPG PG +G  G+ G          KG  GFPG  G          
Sbjct: 691 TGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGK 750

Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
           PG PGPRG  GP GP       + G+ G  GPPG+ G  G  G  G PG  G PGP GS 
Sbjct: 751 PGAPGPRGEDGPEGPKG-----QAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSI 805

Query: 336 DF 337
            F
Sbjct: 806 GF 807



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 52/118 (44%), Positives = 56/118 (47%), Gaps = 32/118 (27%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP-- 304
            GP G  G +G  G+PG KGS G  G  GPPGQPG RG  G   P P  +   QGRRGP  
Sbjct: 1070 GPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAG--HPGPPGADGAQGRRGPPG 1127

Query: 305  ----------------VGPP---GAPGRDGSKGE---------RGAPGPRGSPGPPGS 334
                            +GPP   G PG  G KGE          GAPGPRG  GP GS
Sbjct: 1128 LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS 1185



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 45/101 (44%), Positives = 50/101 (49%), Gaps = 20/101 (19%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPRGSMGPMGPSP 292
            LPGPPG  G  G  GS GP G+P            G PG+PG  GQPG  G  G  G + 
Sbjct: 1152 LPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDA- 1210

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                   G  GP G PG PG  G  GE+G  GP G+ GPPG
Sbjct: 1211 -------GDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG 1244



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/105 (44%), Positives = 51/105 (48%), Gaps = 16/105 (15%)

Query: 245 LPGPPGLPGG------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI- 297
           LPG PGL G       QGP G  GP G PG  G  G PG  G RG  G  GP  D     
Sbjct: 495 LPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDG 554

Query: 298 ------KQGRRGP---VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 ++G+RG    VG PG PG DG +G  G PGP G  G PG
Sbjct: 555 LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 47/111 (42%), Positives = 55/111 (49%), Gaps = 14/111 (12%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---------PRGSM 285
            G+      T  PGP G+ G QG  G  GP G  G PG PGPPG+ G          +G +
Sbjct: 902  GELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL 961

Query: 286  GPMGPSPDLSHIKQGRRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP GP         G RG  GP   PG PG  G KG++G PGP G+ G PG
Sbjct: 962  GPPGPLGKEG--PAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 41/89 (46%), Positives = 47/89 (52%), Gaps = 1/89 (1%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGP 304
            PG PG PG +GP G  G +G  G  G  G PG  GP G  GPMG       +  +G RG 
Sbjct: 1303 PGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP G PG  G+ G+ G PGP G  G PG
Sbjct: 1363 PGPVGEPGLLGAPGQMGPPGPLGPSGLPG 1391



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 46/107 (42%), Positives = 51/107 (47%), Gaps = 23/107 (21%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG------------FPGMPG------PPGQPGPRGSMGP 287
            PGP GL G +GPPG  G  GSPG             PG  G      P G+ G RG  GP
Sbjct: 988  PGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGP 1047

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             GP+      K G  GP+GP G PG  G  GE G  G  G+PG  GS
Sbjct: 1048 PGPTG-----KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGS 1089



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 51/139 (36%), Positives = 55/139 (39%), Gaps = 43/139 (30%)

Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMG-- 289
           V+       GPPG PG QG  G  GP G PGFPG PGPPG       PG  G  GP G  
Sbjct: 383 VIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTV 442

Query: 290 ------------PSPDLSHIK-----------------------QGRRGPVGPPGAPGRD 314
                         P +S  +                        GR GPVG PG PG  
Sbjct: 443 IMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLK 502

Query: 315 GSKGERGAPGPRGSPGPPG 333
           G +G  G  GPRG  GP G
Sbjct: 503 GEEGAEGPQGPRGLQGPHG 521



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 43/93 (46%), Positives = 47/93 (50%), Gaps = 4/93 (4%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI----KQG 300
           LPG PG PG +G  G PGP G  G  G  G  GQPG  G  GP G   +        + G
Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPG 851

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G VG  GAPG  G KG  G  GP G PGP G
Sbjct: 852 PKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKG 884



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G PG  G  GPPG+ GP G  G  G  G PG  G +G  G  GP       + G RGP G
Sbjct: 1055 GIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPG-----QPGIRGPAG 1109

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFL 338
             PG PG DG++G RG PG  G  G  G   F+
Sbjct: 1110 HPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV 1141



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 10/98 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-------PMGPSPDLSHIKQ 299
           G PG PG +G  G  GPKG  G  G  GPPG  G +G +G       P  P P  S    
Sbjct: 749 GKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808

Query: 300 GRRGPVGPPGAPGRDGS---KGERGAPGPRGSPGPPGS 334
           G  GP+G  G  G+ G    +GERG PG RG  G PG+
Sbjct: 809 GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 41/88 (46%), Positives = 45/88 (51%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPV 305
            G  GLPG  G  G  GP G  G  G  GPPG  G  G  GP+GP  P  +    G  G  
Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDK 1078

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GAPG  GSKG++G  GP G PG  G
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRG 1106



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 43/107 (40%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G  GPPG  G  G PG PG+ GP GQ G +GS G MGP  D      G  GP G
Sbjct: 1430 GPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGD-----TGPAGPPG 1484

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQ 353
            PPGAP        R    P   P   G  + +L  L  +  ++ +L+
Sbjct: 1485 PPGAPAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTSLSLELEQLR 1531



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 45/98 (45%), Positives = 48/98 (48%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIK 298
           PGP GL G  GP   PG PG KG  G  G  GP G  GP G  G +G    P  D +   
Sbjct: 481 PGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540

Query: 299 QGRRGPVGP---PGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GP G     G PG  G KG+RG  G  G PGPPG
Sbjct: 541 PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPG 578



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 42/104 (40%), Positives = 51/104 (49%), Gaps = 1/104 (0%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289
           K  +G++ L       G  G PG +G  G  G +G PG PG  G  G  GP+G  G  G 
Sbjct: 715 KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P  S  ++G+ G  G PG PGR G KG  G PGP G  G  G
Sbjct: 775 EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818



 Score = 69.7 bits (169), Expect = 4e-12
 Identities = 37/83 (44%), Positives = 43/83 (51%), Gaps = 8/83 (9%)

Query: 255 QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRD 314
           +GPPG  G  G PG  G+PG PG  G  G+ GP GP        +G +GP GPPG  G+ 
Sbjct: 478 KGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP--------RGLQGPHGPPGRVGKM 529

Query: 315 GSKGERGAPGPRGSPGPPGSFDF 337
           G  G  GA G  G  GP G   F
Sbjct: 530 GRPGADGARGLPGDTGPKGDRGF 552



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/92 (41%), Positives = 43/92 (46%), Gaps = 1/92 (1%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
           + GPPG  G  G PG  G  G PG  G  G  G  GPRG  GP GP   +  + + G  G
Sbjct: 477 MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADG 536

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
             G PG  G  G +G  G PG  G  G  G F
Sbjct: 537 ARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDF 568



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 19/84 (22%)

Query: 258 PGSPGPKGSPGFPGM-------PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGA 310
           PG+ G KG+ G P +        GPPG PGP+G +GP GP            GP G PG 
Sbjct: 370 PGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPP-----------GPPGFPGD 417

Query: 311 PGRDGSKGERGAPGPRGSPGPPGS 334
           PG  G  G  G PG  G  GPPG+
Sbjct: 418 PGPPGPAGLPGIPGIDGIRGPPGT 441


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 98.6 bits (244), Expect = 9e-21
 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 11/88 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGP G PG  GPPG+ G  GSPG PG  GPPG+PG  G  GP GP            G +
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP-----------GAI 221

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G  G+DG  G  G PG RG PGPPG
Sbjct: 222 GPSGPAGKDGESGRPGRPGERGLPGPPG 249



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 5/88 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  GLPG  G PG  G +G  G PG PG PG PGP G +GP G S D     +G  GP 
Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGD-----RGESGPA 1070

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP GAPG  GS+G  G  GPRG  G  G
Sbjct: 1071 GPAGAPGPAGSRGAPGPQGPRGDKGETG 1098



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 1/88 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG PGG G  G PGP GS G  G PGPPG  GPRG  G MG P P  +    G+ G  
Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGER 596

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG  G  G+ G  GP+G PGP G
Sbjct: 597 GGPGGPGPQGPPGKNGETGPQGPPGPTG 624



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 55/113 (48%), Positives = 62/113 (54%), Gaps = 22/113 (19%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMG-PMGPSPDLSHIKQ 299
           GPPG  GG+G  G PGP G+ G PG+ G PG+      PGP+G  G P GP  D    K 
Sbjct: 699 GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKD 758

Query: 300 GRR---GPVGPPGAPGRDGSKGERGAP------GPRGSP------GPPGSFDF 337
           G R   GP+GPPG  G+ G KGE GAP      GPRGSP      GPPG   F
Sbjct: 759 GPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF 811



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 7/95 (7%)

Query: 246 PGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIK 298
           PGPPG PG  G PGSP      GP GSPG  G PG  G+PGP+G  G  G P P   +  
Sbjct: 332 PGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +G +GP G PG  G  G RG PGP G+ G PG
Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG 426



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 49/98 (50%), Positives = 54/98 (55%), Gaps = 11/98 (11%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSH 296
           PGPPG  G  G   PPG  GP+G PG  G PGP      PG+ G RG  GP GP P    
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERG--GPGGPGPQGPP 608

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            K G  GP GPPG  G  G KG+ G PGP+G  G PG+
Sbjct: 609 GKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 8/88 (9%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG  G  G PGSPG +G PG PG  GP G PGP G++GP GP+        G+ G  
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA--------GKDGES 233

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG  G  G  G  GP G PG PG
Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPG 261



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 55/119 (46%), Positives = 65/119 (54%), Gaps = 31/119 (26%)

Query: 246 PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMGP------------ 290
           PG  G+PG +G  GSPGPKG    PG PG  G PG+ GPRG  GP+GP            
Sbjct: 722 PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781

Query: 291 --SPDLSHI--------KQGRRGPVGP---PGAPGRD---GSKGERGAPGPRGSPGPPG 333
             +P L  I        ++G  GP GP   PGAPG++   G KGERGAPG +G  GPPG
Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPG 840



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 48/95 (50%), Positives = 54/95 (56%), Gaps = 7/95 (7%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMGPSPDL----SHIK 298
            PG  G PG QGPPG+PGP G  G  G   + GPPG PGPRGS GP G   +     ++  
Sbjct: 929  PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988

Query: 299  QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G RGP GP G PG  G+ GE G  G  GS G PG
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 44/88 (50%), Positives = 51/88 (57%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305
            G  G+ G +G PG+PG  GSPG  G  G  G PGP G  GP+GPS P       G  GP+
Sbjct: 1101 GAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI 1160

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G +G  G+PG  G PGPPG
Sbjct: 1161 GPPGPRGNRGERGSEGSPGHPGQPGPPG 1188



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 50/110 (45%), Positives = 59/110 (53%), Gaps = 10/110 (9%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--S 291
           TG   L     LPG  G PG  GP G+PG +G PG PG  G  G  G RGS G  GP   
Sbjct: 278 TGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGP 337

Query: 292 PDLSHI--KQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333
           P  +      G +G VGP G+PG +G+ G+RG PGP      +G PGPPG
Sbjct: 338 PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 50/97 (51%), Positives = 52/97 (53%), Gaps = 10/97 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
           G PG PG  G PG PGP GSPG  G PGP G  G  GS G  GP  D     ++G  G  
Sbjct: 879 GLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQ 938

Query: 306 GPPGAPGRDGSKGERGA---------PGPRGSPGPPG 333
           GPPGAPG  G  G  GA         PGPRGSPGP G
Sbjct: 939 GPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 47/91 (51%), Positives = 53/91 (58%), Gaps = 5/91 (5%)

Query: 246 PGP---PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PGP   PG PG  G PG  G +G+PG  G  GPPG  GP G  GP GP P    +K G R
Sbjct: 806 PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP-PGPQGVK-GER 863

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G PGA G  G++G  G PG  G+PGPPG
Sbjct: 864 GSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 48/102 (47%), Positives = 51/102 (50%), Gaps = 15/102 (14%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRG-----SMGPMGPSP--DLSHIKQ 299
           GP G  G  GPPG PG  G PG PG PG PG PGP G       GP   SP  D   +K 
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162

Query: 300 --------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                   G  GP GPPG PG  G+ G  G+PG  G  GPPG
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG 204



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 1/89 (1%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGP 304
           PG  G+PGG G  G PG  G PG  G PGPPG  G  G  GP GPS P       G  GP
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GAPG++G +G  G PGP+G PG  G
Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNG 612



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 49/94 (52%), Positives = 56/94 (59%), Gaps = 8/94 (8%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP-- 304
           GPPG  G +G  GSPG  G+ GFPG  G PG PG  G+ GP GPS   S  K G  GP  
Sbjct: 852 GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG--SPGKDGPPGPAG 909

Query: 305 -VGPPGAPGRDGSKGERGAPGPRGSP---GPPGS 334
             G PG+PG  G KG+ G PG +GSP   GPPG+
Sbjct: 910 NTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGA 943



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 46/96 (47%), Positives = 54/96 (56%), Gaps = 7/96 (7%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF------PGMPGPPGQPGPRGSMGPMG-PSPDLSHI 297
           +PG PGL G +GPPG  G  G+PG       PG  G  G+PGPRG  G  G P    +  
Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           + G+ G  G PGA G  G+ GERGAPG RG  GP G
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 48/105 (45%), Positives = 54/105 (51%), Gaps = 17/105 (16%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSP 292
           LPGPPG+ G  G PG PG KG  GF            PG+ G  G PG  G+ GPMGP  
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
                  G RG  G PGA G  G+ G RG+ G  G PGPPG+  F
Sbjct: 304 -----APGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGF 343



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 48/104 (46%), Positives = 52/104 (50%), Gaps = 23/104 (22%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMP------------GPP---GQPGPRGSMGPMG 289
           LPG  G PG  G PG PGPKG  G PG P            GPP   G PG RG  GP G
Sbjct: 643 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG 702

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P        +G +G  GPPG PG  G+ G +G PG RG  G PG
Sbjct: 703 P--------EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 46/101 (45%), Positives = 49/101 (48%), Gaps = 8/101 (7%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           I G+K  A     PGP G  G  G PG  G  G PG  GMPG PG PG  G  GP G   
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG--- 555

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 QG  G  GPPG  G  G  G  G PGP+G+ G PG
Sbjct: 556 -----SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG 591



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 43/89 (48%), Positives = 47/89 (52%), Gaps = 1/89 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG PG  G PG+ G +G+PGF G  GP G PG +G  G  G P P       G  G  
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG  G  G  G PG  G PGPPGS
Sbjct: 528 GVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 41/88 (46%), Positives = 44/88 (50%), Gaps = 2/88 (2%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  G PG +G  G+PG  G  G PG PGP G PG  G  GP GP         G +G  
Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG--PGGDKGDT 632

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G  G  G PG  G PG PG
Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPG 660



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 47/110 (42%), Positives = 52/110 (47%), Gaps = 19/110 (17%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------- 299
           GP G PG  G PG  G  G+PG PG+ GP G PG RG  GP GP+       Q       
Sbjct: 765 GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGK 824

Query: 300 ------GRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGSFDF 337
                 G +G  GPPG  G  G  G  G PGP      RGSPG PG+  F
Sbjct: 825 GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGF 874



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/91 (50%), Positives = 52/91 (57%), Gaps = 4/91 (4%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
            L GPPG+PG   P GSPGP+G  G  G PG  G  G RG  GP G P    +  + GR G
Sbjct: 958  LAGPPGMPG---PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              G  G PGRDGS G +G  G  GSPG PG+
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 46/104 (44%), Positives = 51/104 (49%), Gaps = 16/104 (15%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGP------------- 290
           G PG  G +G PG PGP+G PG     G  GPPG  GP G  G  GP             
Sbjct: 588 GAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG 647

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            P   + K G  GP G  GAPG  G KG+ GAPG RG PG  G+
Sbjct: 648 GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 45/90 (50%), Positives = 50/90 (55%), Gaps = 8/90 (8%)

Query: 247 GPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           GPPG  G  G PGSP   GPKG  G PG  G PG  GP G+ GP+G    ++ I  G RG
Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG----IAGI-TGARG 957

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GPPG PG  GS G +G  G  G PG  G
Sbjct: 958 LAGPPGMPGPRGSPGPQGVKGESGKPGANG 987



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/91 (49%), Positives = 46/91 (50%), Gaps = 11/91 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PG PG PG  GPPG  GP G  G     G  GP G PGP GS G  GP        QG R
Sbjct: 1040 PGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP--------QGPR 1091

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G  G  G  G KG RG PG  G+PG PG
Sbjct: 1092 GDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 45/101 (44%), Positives = 49/101 (48%), Gaps = 11/101 (10%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            I G +    N   PG PG  G QG  GSPGP G  G  G  GPPG+ G  G  GP+GP  
Sbjct: 1105 IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPP- 1163

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                      GP G  G  G +GS G  G PGP G PG PG
Sbjct: 1164 ----------GPRGNRGERGSEGSPGHPGQPGPPGPPGAPG 1194



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 47/111 (42%), Positives = 55/111 (49%), Gaps = 22/111 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPS----------- 291
           PGP G  G QGPPG PG  GSPG  G  GP   PG PG  G+ GP GP+           
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430

Query: 292 ---PDLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              P  +  K     +G RG  G PG PG  G  G+ G+PG  G+ G PG+
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGA 481



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 42/88 (47%), Positives = 46/88 (52%), Gaps = 5/88 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGP G  G +G  G PGP+G  G PG  GPPG+ G  G  GP G +        G  G  
Sbjct: 620 PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG-----APGAPGGK 674

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GAPG  G  G  GAPG RG  GPPG
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPG 702



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 43/97 (44%), Positives = 48/97 (49%), Gaps = 14/97 (14%)

Query: 246 PGPPGLPGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           PGPPG  G  GP         PG PG +G PG PG+ GP G PG  G  G  G       
Sbjct: 215 PGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG---- 270

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            + G +G  G PG  G +G  GE GAPGP G  G PG
Sbjct: 271 -RNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306



 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 32/77 (41%), Positives = 33/77 (42%), Gaps = 10/77 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G  G PG  GPPG  G +G  G  G PG PGQPGP G  G  GP            G VG
Sbjct: 1152 GTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC----------CGGVG 1201

Query: 307  PPGAPGRDGSKGERGAP 323
                 G  G K    AP
Sbjct: 1202 AAAIAGIGGEKAGGFAP 1218



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 7/65 (10%)

Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGR-RGPVGP------PGAPGRDGSKGERGAPGPRGS 328
           P    P G    + P P  +  +    +GP GP      PG PGR+G  G  G PG  GS
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134

Query: 329 PGPPG 333
           PGPPG
Sbjct: 135 PGPPG 139



 Score = 35.4 bits (80), Expect = 0.093
 Identities = 17/34 (50%), Positives = 20/34 (58%), Gaps = 1/34 (2%)

Query: 246  PGPPGLPGGQGPPGSPGP-KGSPGFPGMPGPPGQ 278
            PG PG PG  GPPG+PGP  G  G   + G  G+
Sbjct: 1178 PGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGE 1211


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287
            PG  G PG +GPPG  GPKG+PG   FPG PGPPG+PGP                G  GP
Sbjct: 1299 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1358

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GPS +      G  G  GPPGA G +G +GE+GA G  G+ GPPG
Sbjct: 1359 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1402



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288
            G PGL GG+GP G PGP GSP            G PG PGP G PGP       G  GP 
Sbjct: 1051 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1110

Query: 289  GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
            GP+  D      G  GP GP G+PG DG KGE G PG +GS         PGPPG
Sbjct: 1111 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G QG PG PG KG  G  G  GPPG PGPRG  GP            G  GP 
Sbjct: 1203 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1251

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG+ G  G  GE+G PG  G+PGPPG
Sbjct: 1252 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301
           PG PG PG  G  G PGPKG+ G  G PGPPGQ   PGP+G  GP GP  P      QG+
Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731

Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G        GPPG PG++G  GE+GA GP G  GP G
Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 769



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282
            GPPGLPG +G PGS G KG PG  G+ GPPG+                        PGP 
Sbjct: 1447 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +GP GP P L     G +GP G  G+ G  G KG+ G PGP GSPGPPG
Sbjct: 1507 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           GP G  G +GP G PGPKG+ G  G PGPPG+ GP+G  GP+G P P         +GP 
Sbjct: 898 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 948

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G  G+RG  G +G  GPPG
Sbjct: 949 GPPGKDGLPGHPGQRGETGFQGKTGPPG 976



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288
            G +     T  PGP G  GG GPPG P      GP+G  GFPG  GPPG PG  G  G  
Sbjct: 901  GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 960

Query: 289  GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G   +     QG+ GP GP G  G  G  GE G  G RG PGPPG
Sbjct: 961  GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%)

Query: 246  PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287
            PGPPG  G QGP G    PGPKG PG P   G+PG PGQ            PGP G +GP
Sbjct: 924  PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 983

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP+ +   I  G RG  GPPG PG  G  G  G  G +G PGP G
Sbjct: 984  QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1027



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284
           TGD   +      G  G+PG  G PG  GPKGS GFPG PG           G+PGPRG 
Sbjct: 834 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 893

Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            GP GP        P      +G  G  GPPG PG  G +G +G    PGP+G PGPPG
Sbjct: 894 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 952



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285
           G  + G    A    + GPPGL G  GPPG PG +G PG PG+PG  G PGP G+M    
Sbjct: 449 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508

Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318
                 G  GP+      +                      GR GPVG PG+ G  G  G
Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568

Query: 319 ERGAPGPRGSPGPPG 333
           + G  GPRG  GPPG
Sbjct: 569 DPGPQGPRGVQGPPG 583



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG  GG+G PG PG KG  GF G+PG PG  G RG  GP G P P      +G  G +
Sbjct: 592 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 651

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G P   G  G RG  GPRG+PG PG
Sbjct: 652 GPRGLP---GEAGPRGLLGPRGTPGAPG 676



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298
           GP GLPG  GP G  GP+G+PG PG P   G  G PGP+G+MGP G P P          
Sbjct: 652 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 711

Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G +GP+GPPG  G  G  G  G PG  G PG PG
Sbjct: 712 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 748



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            + GDK    +   PGPPG  G  GPPG PG +G PG  G  G  G+ G +G  G  GP  
Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1400

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                   G+ GPVGP G  G+ G +G RG PGP G  G PG+
Sbjct: 1401 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP G  G QGPPGS G  G  G  G PG  G PGP G  G  GP  +     +G +G  G
Sbjct: 1243 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1297

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPGA G  G+KG  G  GP+G+PGP G
Sbjct: 1298 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1324



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK         G  G  G  GPPG PG +G  G PG+ G  G+PGPRG  G  G   D 
Sbjct: 1138 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1196

Query: 295  SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333
                +G RG  GPP      G PG  G KGE G  GP G PGPPG
Sbjct: 1197 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1237



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G  GP G  G KG  G PG  GPPG  GP G  GP G    +     G  GP 
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1332

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G+DG  G++G  G  G PGPPG
Sbjct: 1333 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303
            G PG PG QGPPG  G KG+PG  G  GP G+ G   P G  GP GP+   S  + G +G
Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1141

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +G PG  G  G KGE G PGP G  GP G+
Sbjct: 1142 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1172



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+      T  PGP G+ G QGP G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 1015

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               K+G +G  GP G  G+DG  G RG PG RG PG  G+
Sbjct: 1016 ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1052



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293
           PGP GLPG QGP   PG  GP+G PG  G+PG   PPG P      G +G++GP GP   
Sbjct: 708 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 764

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                QG  G  GP G  G DG +G +G+ G +G  G PG
Sbjct: 765 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%)

Query: 235  GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285
            G+K         GPPG     G QGP G PGP+G  G P      G+PG  GQ GP G M
Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446

Query: 286  GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP G  P L     S  ++G  G +G  G PG  G KG+RG PG +GSPG  G
Sbjct: 1447 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1498



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%)

Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283
           AD G+ + G+     +    G PGLPG +G  G  GP+G P   G  GM G  G+ GPRG
Sbjct: 596 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 655

Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP        +G  GP G PGAPG+ G  G  G PGP+G+ GP G
Sbjct: 656 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293
            GPPG PG QGP G+PG  G  G PG  G  G             PGP G +G  G P P 
Sbjct: 1159 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1218

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                + G  GP+GPPG PG  G +G  GA GP+G PG  GS
Sbjct: 1219 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301
           PGP GL G  GP G PG  G+ G  G PGP G   PRG  GP GP+      K+GR    
Sbjct: 543 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 597

Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333
             RG  G PGA         PG  G KG RG  GP+G PGPPG
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 640



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299
           GP G  G  GP G PGP      KG  G PG+PG PG+ GP+GS G P  P  +     +
Sbjct: 823 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G  G  GP G  G  G +G RGA GP G PGP G+
Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 917



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP GLPG  GP GSPG  G  G  G PG  G  G +G  GP GP         G +GPVG
Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1171

Query: 307  PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333
             PG  G DG  G RG           G RG PGPPG
Sbjct: 1172 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%)

Query: 246  PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284
            PGPPG PG QG PG+         PGP            +G PG  G+PG  G PG +G 
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 285  MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333
             GP G P P  S  ++G  G  GP G PGR G +      GE+GAPG +G  GP G
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1114



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
            GP GL G  G  G PG +G+PG  G  GP G PGP GS G  G +     I   GR GP 
Sbjct: 1033 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1092

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G+ GE+G  GP G  G  G
Sbjct: 1093 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296
            PGPPG  G QGP G+ GP+G PG  G          PG  G PGP G  G  GP  +   
Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1289

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
              +G +G  GPPGA G  G+KG    PG  G  G PG   F
Sbjct: 1290 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1325



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298
           PG  GLPG  GPPG PG +G  G  G  GPPG  GP G  GP G   +  +  +K     
Sbjct: 732 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791

Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                          +G RG VG  G  G DG +G +G  GP G PGP G
Sbjct: 792 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 841



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301
           PGP G+ G  G     GS G KG  GFPG  G  G  G RG +G +GP   D     +GR
Sbjct: 771 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 830

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337
            GP G PG  G+ G KG+ G PG     G  GP GS  F
Sbjct: 831 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 869



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G  G +G  G  GPKG  G  G PGP GQ G +G +G  G  P     +QG +G  G
Sbjct: 811 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 868

Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            PG PG +G KG RG    PGPRG  GP G
Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 898



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%)

Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309
           G G  G  G KG P    PGM   GPPG  GP G MGP            G +GP GPPG
Sbjct: 430 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 478

Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334
            PG  G  G  G PG  G PGPPG+
Sbjct: 479 DPGDRGPPGRPGLPGADGLPGPPGT 503



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%)

Query: 246  PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
            PGPPGLPG QGP    GS GP G  G  G+PGPPG PGP G +  + P P LS  K  R
Sbjct: 1512 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1568


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287
            PG  G PG +GPPG  GPKG+PG   FPG PGPPG+PGP                G  GP
Sbjct: 1248 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1307

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GPS +      G  G  GPPGA G +G +GE+GA G  G+ GPPG
Sbjct: 1308 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1351



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288
            G PGL GG+GP G PGP GSP            G PG PGP G PGP       G  GP 
Sbjct: 1000 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1059

Query: 289  GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
            GP+  D      G  GP GP G+PG DG KGE G PG +GS         PGPPG
Sbjct: 1060 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G QG PG PG KG  G  G  GPPG PGPRG  GP            G  GP 
Sbjct: 1152 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1200

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG+ G  G  GE+G PG  G+PGPPG
Sbjct: 1201 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301
           PG PG PG  G  G PGPKG+ G  G PGPPGQ   PGP+G  GP GP  P      QG+
Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680

Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G        GPPG PG++G  GE+GA GP G  GP G
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 718



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282
            GPPGLPG +G PGS G KG PG  G+ GPPG+                        PGP 
Sbjct: 1396 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +GP GP P L     G +GP G  G+ G  G KG+ G PGP GSPGPPG
Sbjct: 1456 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           GP G  G +GP G PGPKG+ G  G PGPPG+ GP+G  GP+G P P         +GP 
Sbjct: 847 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 897

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G  G+RG  G +G  GPPG
Sbjct: 898 GPPGKDGLPGHPGQRGETGFQGKTGPPG 925



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288
           G +     T  PGP G  GG GPPG P      GP+G  GFPG  GPPG PG  G  G  
Sbjct: 850 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 909

Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G   +     QG+ GP GP G  G  G  GE G  G RG PGPPG
Sbjct: 910 GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%)

Query: 246 PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287
           PGPPG  G QGP G    PGPKG PG P   G+PG PGQ            PGP G +GP
Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 932

Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+ +   I  G RG  GPPG PG  G  G  G  G +G PGP G
Sbjct: 933 QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 976



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284
           TGD   +      G  G+PG  G PG  GPKGS GFPG PG           G+PGPRG 
Sbjct: 783 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 842

Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            GP GP        P      +G  G  GPPG PG  G +G +G    PGP+G PGPPG
Sbjct: 843 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 901



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285
           G  + G    A    + GPPGL G  GPPG PG +G PG PG+PG  G PGP G+M    
Sbjct: 398 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457

Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318
                 G  GP+      +                      GR GPVG PG+ G  G  G
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517

Query: 319 ERGAPGPRGSPGPPG 333
           + G  GPRG  GPPG
Sbjct: 518 DPGPQGPRGVQGPPG 532



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG  GG+G PG PG KG  GF G+PG PG  G RG  GP G P P      +G  G +
Sbjct: 541 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 600

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G P   G  G RG  GPRG+PG PG
Sbjct: 601 GPRGLP---GEAGPRGLLGPRGTPGAPG 625



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298
           GP GLPG  GP G  GP+G+PG PG P   G  G PGP+G+MGP G P P          
Sbjct: 601 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660

Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G +GP+GPPG  G  G  G  G PG  G PG PG
Sbjct: 661 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 697



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            + GDK    +   PGPPG  G  GPPG PG +G PG  G  G  G+ G +G  G  GP  
Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1349

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                   G+ GPVGP G  G+ G +G RG PGP G  G PG+
Sbjct: 1350 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP G  G QGPPGS G  G  G  G PG  G PGP G  G  GP  +     +G +G  G
Sbjct: 1192 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1246

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPGA G  G+KG  G  GP+G+PGP G
Sbjct: 1247 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1273



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK         G  G  G  GPPG PG +G  G PG+ G  G+PGPRG  G  G   D 
Sbjct: 1087 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1145

Query: 295  SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333
                +G RG  GPP      G PG  G KGE G  GP G PGPPG
Sbjct: 1146 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1186



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G  GP G  G KG  G PG  GPPG  GP G  GP G    +     G  GP 
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1281

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G+DG  G++G  G  G PGPPG
Sbjct: 1282 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303
            G PG PG QGPPG  G KG+PG  G  GP G+ G   P G  GP GP+   S  + G +G
Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1090

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +G PG  G  G KGE G PGP G  GP G+
Sbjct: 1091 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1121



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+      T  PGP G+ G QGP G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 964

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               K+G +G  GP G  G+DG  G RG PG RG PG  G+
Sbjct: 965  ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1001



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293
           PGP GLPG QGP   PG  GP+G PG  G+PG   PPG P      G +G++GP GP   
Sbjct: 657 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 713

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                QG  G  GP G  G DG +G +G+ G +G  G PG
Sbjct: 714 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%)

Query: 235  GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285
            G+K         GPPG     G QGP G PGP+G  G P      G+PG  GQ GP G M
Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395

Query: 286  GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP G  P L     S  ++G  G +G  G PG  G KG+RG PG +GSPG  G
Sbjct: 1396 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1447



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%)

Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283
           AD G+ + G+     +    G PGLPG +G  G  GP+G P   G  GM G  G+ GPRG
Sbjct: 545 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 604

Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP        +G  GP G PGAPG+ G  G  G PGP+G+ GP G
Sbjct: 605 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293
            GPPG PG QGP G+PG  G  G PG  G  G             PGP G +G  G P P 
Sbjct: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1167

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                + G  GP+GPPG PG  G +G  GA GP+G PG  GS
Sbjct: 1168 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301
           PGP GL G  GP G PG  G+ G  G PGP G   PRG  GP GP+      K+GR    
Sbjct: 492 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 546

Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333
             RG  G PGA         PG  G KG RG  GP+G PGPPG
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 589



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299
           GP G  G  GP G PGP      KG  G PG+PG PG+ GP+GS G P  P  +     +
Sbjct: 772 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G  G  GP G  G  G +G RGA GP G PGP G+
Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 866



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP GLPG  GP GSPG  G  G  G PG  G  G +G  GP GP         G +GPVG
Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1120

Query: 307  PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333
             PG  G DG  G RG           G RG PGPPG
Sbjct: 1121 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%)

Query: 246  PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284
            PGPPG PG QG PG+         PGP            +G PG  G+PG  G PG +G 
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 285  MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333
             GP G P P  S  ++G  G  GP G PGR G +      GE+GAPG +G  GP G
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
            GP GL G  G  G PG +G+PG  G  GP G PGP GS G  G +     I   GR GP 
Sbjct: 982  GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G+ GE+G  GP G  G  G
Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296
            PGPPG  G QGP G+ GP+G PG  G          PG  G PGP G  G  GP  +   
Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1238

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
              +G +G  GPPGA G  G+KG    PG  G  G PG   F
Sbjct: 1239 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1274



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298
           PG  GLPG  GPPG PG +G  G  G  GPPG  GP G  GP G   +  +  +K     
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740

Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                          +G RG VG  G  G DG +G +G  GP G PGP G
Sbjct: 741 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 790



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301
           PGP G+ G  G     GS G KG  GFPG  G  G  G RG +G +GP   D     +GR
Sbjct: 720 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 779

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337
            GP G PG  G+ G KG+ G PG     G  GP GS  F
Sbjct: 780 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 818



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G  G +G  G  GPKG  G  G PGP GQ G +G +G  G  P     +QG +G  G
Sbjct: 760 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 817

Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            PG PG +G KG RG    PGPRG  GP G
Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 847



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%)

Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309
           G G  G  G KG P    PGM   GPPG  GP G MGP            G +GP GPPG
Sbjct: 379 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 427

Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334
            PG  G  G  G PG  G PGPPG+
Sbjct: 428 DPGDRGPPGRPGLPGADGLPGPPGT 452



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%)

Query: 246  PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
            PGPPGLPG QGP    GS GP G  G  G+PGPPG PGP G +  + P P LS  K  R
Sbjct: 1461 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1517


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 51/106 (48%), Positives = 59/106 (55%), Gaps = 20/106 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPR---------------GSMGP 287
            PG  G PG +GPPG  GPKG+PG   FPG PGPPG+PGP                G  GP
Sbjct: 1287 PGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGP 1346

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GPS +      G  G  GPPGA G +G +GE+GA G  G+ GPPG
Sbjct: 1347 PGPSGEAG--PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPG 1390



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 54/115 (46%), Positives = 58/115 (50%), Gaps = 28/115 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSP------------GFPGMPGPPGQPGPR------GSMGPM 288
            G PGL GG+GP G PGP GSP            G PG PGP G PGP       G  GP 
Sbjct: 1039 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1098

Query: 289  GPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
            GP+  D      G  GP GP G+PG DG KGE G PG +GS         PGPPG
Sbjct: 1099 GPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 47/88 (53%), Positives = 50/88 (56%), Gaps = 11/88 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G QG PG PG KG  G  G  GPPG PGPRG  GP            G  GP 
Sbjct: 1191 PGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGP-----------NGADGPQ 1239

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG+ G  G  GE+G PG  G+PGPPG
Sbjct: 1240 GPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 50/98 (51%), Positives = 56/98 (57%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGP-SPDLSHIKQGR 301
           PG PG PG  G  G PGPKG+ G  G PGPPGQ   PGP+G  GP GP  P      QG+
Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719

Query: 302 RGPV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G        GPPG PG++G  GE+GA GP G  GP G
Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 757



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 51/111 (45%), Positives = 58/111 (52%), Gaps = 29/111 (26%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------------------PGPR 282
            GPPGLPG +G PGS G KG PG  G+ GPPG+                        PGP 
Sbjct: 1435 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +GP GP P L     G +GP G  G+ G  G KG+ G PGP GSPGPPG
Sbjct: 1495 GPLGPPGP-PGL----PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 44/88 (50%), Positives = 52/88 (59%), Gaps = 10/88 (11%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           GP G  G +GP G PGPKG+ G  G PGPPG+ GP+G  GP+G P P         +GP 
Sbjct: 886 GPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPP 936

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G  G+RG  G +G  GPPG
Sbjct: 937 GPPGKDGLPGHPGQRGETGFQGKTGPPG 964



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 49/105 (46%), Positives = 53/105 (50%), Gaps = 8/105 (7%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSP------GPKGSPGFPGMPGPPGQPGPRGSMGPM 288
           G +     T  PGP G  GG GPPG P      GP+G  GFPG  GPPG PG  G  G  
Sbjct: 889 GSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHP 948

Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G   +     QG+ GP GP G  G  G  GE G  G RG PGPPG
Sbjct: 949 GQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 51/106 (48%), Positives = 56/106 (52%), Gaps = 20/106 (18%)

Query: 246  PGPPGLPGGQGPPGS---PGPKGSPGFP---GMPGPPGQ------------PGPRGSMGP 287
            PGPPG  G QGP G    PGPKG PG P   G+PG PGQ            PGP G +GP
Sbjct: 912  PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGP 971

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP+ +   I  G RG  GPPG PG  G  G  G  G +G PGP G
Sbjct: 972  QGPTGETGPI--GERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1015



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 52/119 (43%), Positives = 59/119 (49%), Gaps = 19/119 (15%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGS 284
           TGD   +      G  G+PG  G PG  GPKGS GFPG PG           G+PGPRG 
Sbjct: 822 TGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQ 881

Query: 285 MGPMGP-------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            GP GP        P      +G  G  GPPG PG  G +G +G    PGP+G PGPPG
Sbjct: 882 RGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG 940



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/135 (37%), Positives = 60/135 (44%), Gaps = 31/135 (22%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM---- 285
           G  + G    A    + GPPGL G  GPPG PG +G PG PG+PG  G PGP G+M    
Sbjct: 437 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496

Query: 286 ------GPMGPSPDLSHIK---------------------QGRRGPVGPPGAPGRDGSKG 318
                 G  GP+      +                      GR GPVG PG+ G  G  G
Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556

Query: 319 ERGAPGPRGSPGPPG 333
           + G  GPRG  GPPG
Sbjct: 557 DPGPQGPRGVQGPPG 571



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 45/88 (51%), Positives = 50/88 (56%), Gaps = 4/88 (4%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G PG  GG+G PG PG KG  GF G+PG PG  G RG  GP G P P      +G  G +
Sbjct: 580 GRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 639

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G P   G  G RG  GPRG+PG PG
Sbjct: 640 GPRGLP---GEAGPRGLLGPRGTPGAPG 664



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 47/97 (48%), Positives = 53/97 (54%), Gaps = 10/97 (10%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMP---GPPGQPGPRGSMGPMG-PSPDLSHIK---- 298
           GP GLPG  GP G  GP+G+PG PG P   G  G PGP+G+MGP G P P          
Sbjct: 640 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 699

Query: 299 --QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G +GP+GPPG  G  G  G  G PG  G PG PG
Sbjct: 700 GLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 736



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 45/102 (44%), Positives = 54/102 (52%), Gaps = 8/102 (7%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            + GDK    +   PGPPG  G  GPPG PG +G PG  G  G  G+ G +G  G  GP  
Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP-- 1388

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                   G+ GPVGP G  G+ G +G RG PGP G  G PG+
Sbjct: 1389 ------PGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 43/87 (49%), Positives = 49/87 (56%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP G  G QGPPGS G  G  G  G PG  G PGP G  G  GP  +     +G +G  G
Sbjct: 1231 GPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE-----RGEKGEAG 1285

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPGA G  G+KG  G  GP+G+PGP G
Sbjct: 1286 PPGAAGPPGAKGPPGDDGPKGNPGPVG 1312



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/105 (45%), Positives = 52/105 (49%), Gaps = 11/105 (10%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK         G  G  G  GPPG PG +G  G PG+ G  G+PGPRG  G  G   D 
Sbjct: 1126 GDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD- 1184

Query: 295  SHIKQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSPGPPG 333
                +G RG  GPP      G PG  G KGE G  GP G PGPPG
Sbjct: 1185 ----EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG 1225



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 2/88 (2%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G  GP G  G KG  G PG  GPPG  GP G  GP G    +     G  GP 
Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF--PGDPGPP 1320

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G+DG  G++G  G  G PGPPG
Sbjct: 1321 GEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/91 (49%), Positives = 52/91 (57%), Gaps = 5/91 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHIKQGRRG 303
            G PG PG QGPPG  G KG+PG  G  GP G+ G   P G  GP GP+   S  + G +G
Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAG--SPGEDGDKG 1129

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +G PG  G  G KGE G PGP G  GP G+
Sbjct: 1130 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGA 1160



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 44/100 (44%), Positives = 52/100 (52%), Gaps = 11/100 (11%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+      T  PGP G+ G QGP G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAG-------- 1003

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               K+G +G  GP G  G+DG  G RG PG RG PG  G+
Sbjct: 1004 ---KEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA 1040



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/100 (46%), Positives = 55/100 (55%), Gaps = 20/100 (20%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPG---PPGQP------GPRGSMGPMGPSPD 293
           PGP GLPG QGP   PG  GP+G PG  G+PG   PPG P      G +G++GP GP   
Sbjct: 696 PGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP--- 752

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                QG  G  GP G  G DG +G +G+ G +G  G PG
Sbjct: 753 -----QGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 50/113 (44%), Positives = 58/113 (51%), Gaps = 15/113 (13%)

Query: 235  GDKVLASNTYLPGPPGLP---GGQGPPGSPGPKGSPGFP------GMPGPPGQPGPRGSM 285
            G+K         GPPG     G QGP G PGP+G  G P      G+PG  GQ GP G M
Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434

Query: 286  GPMGPSPDL-----SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP G  P L     S  ++G  G +G  G PG  G KG+RG PG +GSPG  G
Sbjct: 1435 GPPG-LPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKG 1486



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/110 (42%), Positives = 58/110 (52%), Gaps = 11/110 (10%)

Query: 227 ADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP---GFPGMPGPPGQPGPRG 283
           AD G+ + G+     +    G PGLPG +G  G  GP+G P   G  GM G  G+ GPRG
Sbjct: 584 ADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRG 643

Query: 284 SMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  GP        +G  GP G PGAPG+ G  G  G PGP+G+ GP G
Sbjct: 644 LPGEAGP--------RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 46/101 (45%), Positives = 52/101 (51%), Gaps = 13/101 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------------PGPRGSMGPMG-PSPD 293
            GPPG PG QGP G+PG  G  G PG  G  G             PGP G +G  G P P 
Sbjct: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPP 1206

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                + G  GP+GPPG PG  G +G  GA GP+G PG  GS
Sbjct: 1207 GEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 20/103 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR---- 301
           PGP GL G  GP G PG  G+ G  G PGP G   PRG  GP GP+      K+GR    
Sbjct: 531 PGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG---PRGVQGPPGPTGKPG--KRGRPGAD 585

Query: 302 --RGPVGPPGA---------PGRDGSKGERGAPGPRGSPGPPG 333
             RG  G PGA         PG  G KG RG  GP+G PGPPG
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPG 628



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 44/95 (46%), Positives = 51/95 (53%), Gaps = 7/95 (7%)

Query: 247 GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQ 299
           GP G  G  GP G PGP      KG  G PG+PG PG+ GP+GS G P  P  +     +
Sbjct: 811 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 870

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G  G  GP G  G  G +G RGA GP G PGP G+
Sbjct: 871 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 905



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 45/96 (46%), Positives = 47/96 (48%), Gaps = 17/96 (17%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP GLPG  GP GSPG  G  G  G PG  G  G +G  GP GP         G +GPVG
Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPP--------GLQGPVG 1159

Query: 307  PPGAPGRDGSKGERGA---------PGPRGSPGPPG 333
             PG  G DG  G RG           G RG PGPPG
Sbjct: 1160 APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 49/116 (42%), Positives = 58/116 (50%), Gaps = 28/116 (24%)

Query: 246  PGPPGLPGGQGPPGS---------PGP------------KGSPGFPGMPGPPGQPGPRGS 284
            PGPPG PG QG PG+         PGP            +G PG  G+PG  G PG +G 
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 285  MGPMG-PSPDLSHIKQGRRGPVGPPGAPGRDGSK------GERGAPGPRGSPGPPG 333
             GP G P P  S  ++G  G  GP G PGR G +      GE+GAPG +G  GP G
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/88 (47%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRGPV 305
            GP GL G  G  G PG +G+PG  G  GP G PGP GS G  G +     I   GR GP 
Sbjct: 1021 GPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G+ GE+G  GP G  G  G
Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/101 (43%), Positives = 50/101 (49%), Gaps = 17/101 (16%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296
            PGPPG  G QGP G+ GP+G PG  G          PG  G PGP G  G  GP  +   
Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE--- 1277

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
              +G +G  GPPGA G  G+KG    PG  G  G PG   F
Sbjct: 1278 --RGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGF 1313



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 44/110 (40%), Positives = 51/110 (46%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIK----- 298
           PG  GLPG  GPPG PG +G  G  G  GPPG  GP G  GP G   +  +  +K     
Sbjct: 720 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779

Query: 299 ---------------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                          +G RG VG  G  G DG +G +G  GP G PGP G
Sbjct: 780 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSG 829



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/99 (44%), Positives = 50/99 (50%), Gaps = 7/99 (7%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301
           PGP G+ G  G     GS G KG  GFPG  G  G  G RG +G +GP   D     +GR
Sbjct: 759 PGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGR 818

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPR---GSPGPPGSFDF 337
            GP G PG  G+ G KG+ G PG     G  GP GS  F
Sbjct: 819 AGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGF 857



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 42/90 (46%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G  G +G  G  GPKG  G  G PGP GQ G +G +G  G  P     +QG +G  G
Sbjct: 799 GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG-LPGYPG-RQGPKGSTG 856

Query: 307 PPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            PG PG +G KG RG    PGPRG  GP G
Sbjct: 857 FPGFPGANGEKGARGVAGKPGPRGQRGPTG 886



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 40/85 (47%), Positives = 42/85 (49%), Gaps = 15/85 (17%)

Query: 254 GQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPG 309
           G G  G  G KG P    PGM   GPPG  GP G MGP            G +GP GPPG
Sbjct: 418 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP-----------PGLQGPTGPPG 466

Query: 310 APGRDGSKGERGAPGPRGSPGPPGS 334
            PG  G  G  G PG  G PGPPG+
Sbjct: 467 DPGDRGPPGRPGLPGADGLPGPPGT 491



 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 5/59 (8%)

Query: 246  PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
            PGPPGLPG QGP    GS GP G  G  G+PGPPG PGP G +  + P P LS  K  R
Sbjct: 1500 PGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV--IQPLPILSSKKTRR 1556


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 50/99 (50%), Positives = 56/99 (56%), Gaps = 10/99 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMG-------PSPDLS 295
           PGPPG PG  G PG PGP+G+   PGF G  G  G PGPRG  G MG       P  D  
Sbjct: 698 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               G +GP GP G PG++GS G  G PGP G+PG  GS
Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 796



 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 47/92 (51%), Positives = 55/92 (59%), Gaps = 6/92 (6%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMGPS--PDLSHIKQGR 301
           G PG+PG  GPPG+PGP G+ G  G  GPP   G PG  G  GP GPS  P +   ++G+
Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG-EEGK 691

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G PG PG  G  GE G PGP G+ GPPG
Sbjct: 692 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 723



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 48/99 (48%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS------------MGPMGPSPDL 294
           GP G  G QGP G PG  GSPG PG PGP G PG +GS            +GP GP  + 
Sbjct: 759 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              ++G  G  G PG PG  G KGERG PG +G  GPPG
Sbjct: 819 G--EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 855



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 47/100 (47%), Positives = 53/100 (53%), Gaps = 13/100 (13%)

Query: 247 GPPGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQ 299
           GPPG  G  G  G+PGP+G       PG  G+PG  G  GP G  GP GP  P   +   
Sbjct: 720 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779

Query: 300 GRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPG 333
           G  G  GP G PG+ GSKGE G+P      GPRG PG PG
Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 11/102 (10%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GD  L     L G PG  G QGP G PG KG  G  G PG  G PG  G +G  GPS   
Sbjct: 356 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS--- 412

Query: 295 SHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333
                G  G VG P   G PG+DG +GE+GA G  GSPGP G
Sbjct: 413 -----GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 449



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/109 (42%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQG-------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285
           + GD+         GPPGLPG           PG  GPKG  G PG+PG PG  G  G +
Sbjct: 314 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 373

Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           GP GP+       +G+ G  G PGA G  G+ G  GAPGP G PG  G+
Sbjct: 374 GPQGPTGPPG--AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 420



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/93 (48%), Positives = 51/93 (54%), Gaps = 4/93 (4%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
           +PG PG  G +G  G  GP G PG PG+ GP G  G RG+ G +G   D  H    G  G
Sbjct: 583 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 642

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333
           P G PG PG DG  G  G PG +GSP   GPPG
Sbjct: 643 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 675



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 44/93 (47%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG PG  G PG  GP G PG PG  G  G  GP G  G  G   D      G RG +
Sbjct: 946  PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEM 1005

Query: 306  GPPGAPGRDGSKGER-----GAPGPRGSPGPPG 333
            GPPG PG+ G  G       G PGP+G  GP G
Sbjct: 1006 GPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1038



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 45/95 (47%), Positives = 50/95 (52%), Gaps = 14/95 (14%)

Query: 246 PGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PGPPGLPG       +G PG PG +G+ G  G  GPPG PGP G  GP G         Q
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG--------SQ 617

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G RG  G  G  G  G  G  G  GP G+PGPPG+
Sbjct: 618 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 652



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 43/88 (48%), Positives = 49/88 (55%), Gaps = 5/88 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PG  G +GPPG PG KG PG  G+PG PG+PG +G  G  G   D     +G  G  
Sbjct: 803 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD-----KGPPGGK 857

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G PG PG  G KG  G  GP+G PG  G
Sbjct: 858 GQPGDPGIPGHKGHTGLMGPQGLPGENG 885



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 49/106 (46%), Positives = 54/106 (50%), Gaps = 12/106 (11%)

Query: 240 ASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           A N   PG  G PG  GPPGS   PG +G+PG  G  G  G  G  GS GP+GP  D   
Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGA 456

Query: 297 I---------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                     K G  G  G PG PG  G+KG+RGAPG  GSPG  G
Sbjct: 457 PGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG 502



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 46/102 (45%), Positives = 55/102 (53%), Gaps = 4/102 (3%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           G+K  A     PGP G  G  G PG PGP  KG  G PG+ G PG PGP G+ G  G +P
Sbjct: 434 GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRG-AP 492

Query: 293 DLSHIKQGRRGP-VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +      R  P +G  G PG  G  G++G+PG RG PG PG
Sbjct: 493 GIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 54/146 (36%), Positives = 69/146 (47%), Gaps = 42/146 (28%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM-----PGPPGQPGPRGS 284
           GK   G+  L  +  LPGP G  G +G PG PG  GS G PG+     PGP G PG +GS
Sbjct: 464 GKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGS 523

Query: 285 ---------MGPMGP----------SP-DLSHIKQ-----------------GRRGPVGP 307
                     GP GP          SP D++ + +                 G +G  G 
Sbjct: 524 PGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGV 583

Query: 308 PGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG PGR+G++G++G  GP G PGPPG
Sbjct: 584 PGKPGREGTEGKKGEAGPPGLPGPPG 609



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/134 (38%), Positives = 57/134 (42%), Gaps = 33/134 (24%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           I GDK        PG PG+PG +G  G  GP+G PG  G  GPPG PG  G  G  G SP
Sbjct: 847 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 906

Query: 293 DLSHIK------------------------------QGRRGPVGPP---GAPGRDGSKGE 319
            +  ++                              QGR GP GPP   G PGR G  GE
Sbjct: 907 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 966

Query: 320 RGAPGPRGSPGPPG 333
            G PG  G  GP G
Sbjct: 967 PGRPGQGGLEGPSG 980



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/99 (42%), Positives = 51/99 (51%), Gaps = 10/99 (10%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---------PSPDLS 295
           LPG PG PG +G  G  G KG  G PG+ G  G+ G  G  GP G         P P + 
Sbjct: 287 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 346

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +QG +G  G PG PG  G +G  G  GP+G  GPPG+
Sbjct: 347 G-EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 384



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/110 (43%), Positives = 54/110 (49%), Gaps = 7/110 (6%)

Query: 246 PGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           PG PGLPG  G+G  G PG +GSPG PG  G  G  G  G  G  G   D      G  G
Sbjct: 454 PGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPG 513

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL-----LMLADIRND 348
           P GPPG  G  GS+G  G PGP+G  G  G    L      L+  D+ ND
Sbjct: 514 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCND 563



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/86 (48%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 248  PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307
            P  +   QG PG PGP G  G PG  GP G+PG  G  G  GPS  +    +G RG  G 
Sbjct: 936  PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--PKGERGAKGD 993

Query: 308  PGAPGRDGSKGERGAPGPRGSPGPPG 333
            PGAPG  G +GE G PG  G PG PG
Sbjct: 994  PGAPG-VGLRGEMGPPGIPGQPGEPG 1018



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 46/123 (37%), Positives = 53/123 (43%), Gaps = 20/123 (16%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
           K + G+        LPG PGL G  G  G  G  G  G  G+PG PG PG RG  G  G 
Sbjct: 246 KQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGE 305

Query: 291 SPDL-------SHIKQGRRGPVGPPG-------------APGRDGSKGERGAPGPRGSPG 330
             +L          ++G  GP GPPG              PG  G KGE+G PG  G PG
Sbjct: 306 KGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 365

Query: 331 PPG 333
             G
Sbjct: 366 LQG 368



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 41/90 (45%), Positives = 47/90 (52%), Gaps = 8/90 (8%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS 291
           G+K +     +PG PG PG +G  G PG KG  G PG  G PG    PG +G  G MGP 
Sbjct: 819 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 878

Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321
                   G  GPVGPPG PG+ G  G RG
Sbjct: 879 G-----LPGENGPVGPPGPPGQPGFPGLRG 903



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 49/132 (37%), Positives = 56/132 (42%), Gaps = 40/132 (30%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGM------------------------------PGPP 276
           GPPG  G  G  GSPG +G PGFPG                               PGPP
Sbjct: 510 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569

Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVG---PPGAPGRDGSKGERGAPGP---R 326
           G PG  G  G  G    P  + +  K+G  GP G   PPG  G  GS+GERGA G    +
Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629

Query: 327 GSPGPPGSFDFL 338
           G  G PG   F+
Sbjct: 630 GDQGHPGVPGFM 641



 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 40/104 (38%), Positives = 51/104 (49%), Gaps = 11/104 (10%)

Query: 238 VLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMG-PMGP 290
           +LA+ T     PGL    G PG  G  G PG PG+ G        G+PG +G  G P  P
Sbjct: 236 ILAAKT----APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 291

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                  ++G +G  G  G PG  G +GE+G  GP G PG PG+
Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 335



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 23/92 (25%)

Query: 247  GPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            GP G  G +G PG+PG   +G  G PG+PG PG+PG               + K G    
Sbjct: 983  GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG---------------YAKDGL--- 1024

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
               PG PG  G  G  G PG  G PGPPG  D
Sbjct: 1025 ---PGIPGPQGETGPAGHPGLPGPPGPPGQCD 1053



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 24/41 (58%), Positives = 24/41 (58%), Gaps = 5/41 (12%)

Query: 246  PGPPG-----LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281
            PG PG     LPG  GP G  GP G PG PG PGPPGQ  P
Sbjct: 1014 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1054



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 29/62 (46%), Positives = 31/62 (50%), Gaps = 16/62 (25%)

Query: 246  PGPPG--LPGGQGPPGSPGPKGSPGF-----PGMPGP---------PGQPGPRGSMGPMG 289
            PG PG  L G  GPPG PG  G PG+     PG+PGP         PG PGP G  G   
Sbjct: 994  PGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1053

Query: 290  PS 291
            PS
Sbjct: 1054 PS 1055



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 24/45 (53%), Positives = 26/45 (57%), Gaps = 2/45 (4%)

Query: 245  LPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287
            +PG PG PG    G PG PGP+G  G  G PG PG PGP G   P
Sbjct: 1010 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1054



 Score = 35.8 bits (81), Expect = 0.071
 Identities = 25/68 (36%), Positives = 29/68 (42%), Gaps = 17/68 (25%)

Query: 270 PGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP 329
           PG+    G+PG RG  G  G        K G RG +G  G  GR G KGE          
Sbjct: 243 PGLKQLNGEPGERGEDGLPG--------KPGLRGEIGEQGLAGRPGEKGE---------A 285

Query: 330 GPPGSFDF 337
           G PG+  F
Sbjct: 286 GLPGAPGF 293



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277
            G PGLPG  GPPG   P     F  +   PG
Sbjct: 1038 GHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1068


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 97.4 bits (241), Expect = 2e-20
 Identities = 50/99 (50%), Positives = 56/99 (56%), Gaps = 10/99 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMG-------PSPDLS 295
            PGPPG PG  G PG PGP+G+   PGF G  G  G PGPRG  G MG       P  D  
Sbjct: 1251 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310

Query: 296  HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                G +GP GP G PG++GS G  G PGP G+PG  GS
Sbjct: 1311 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349



 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 47/92 (51%), Positives = 55/92 (59%), Gaps = 6/92 (6%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG---QPGPRGSMGPMGPS--PDLSHIKQGR 301
            G PG+PG  GPPG+PGP G+ G  G  GPPG    PG  G  GP GPS  P +   ++G+
Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG-EEGK 1244

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G PG PG  G  GE G PGP G+ GPPG
Sbjct: 1245 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 50/96 (52%), Positives = 56/96 (58%), Gaps = 4/96 (4%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
           PGPPG+PG  GP GSPG  G  GFPG PGPPG  GP G  GP G P P  +  + G RG 
Sbjct: 716 PGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGE 775

Query: 305 VGPPGAPGRDGSKGER---GAPGPRGSPGPPGSFDF 337
            G PG PG  G  GE+   G PG +G  G PG+  F
Sbjct: 776 DGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGF 811



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 48/99 (48%), Positives = 54/99 (54%), Gaps = 14/99 (14%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS------------MGPMGPSPDL 294
            GP G  G QGP G PG  GSPG PG PGP G PG +GS            +GP GP  + 
Sbjct: 1312 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 1371

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               ++G  G  G PG PG  G KGERG PG +G  GPPG
Sbjct: 1372 G--EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPG 1408



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 47/100 (47%), Positives = 53/100 (53%), Gaps = 13/100 (13%)

Query: 247  GPPGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQ 299
            GPPG  G  G  G+PGP+G       PG  G+PG  G  GP G  GP GP  P   +   
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 300  GRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPG 333
            G  G  GP G PG+ GSKGE G+P      GPRG PG PG
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 1372



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 48/94 (51%), Positives = 50/94 (53%), Gaps = 14/94 (14%)

Query: 246 PGPPGLPGGQGPPGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PG PGL G QGPPG PG      P GSPG PG  G PG+PGP G  GP G        K 
Sbjct: 704 PGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPG--------KD 755

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  GP GPPG  G  G +GE G PG  G  G  G
Sbjct: 756 GPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIG 789



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/102 (48%), Positives = 53/102 (51%), Gaps = 11/102 (10%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GD  L     L G PG  G QGP G PG KG  G  G PG  G PG  G +G  GPS   
Sbjct: 874 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS--- 930

Query: 295 SHIKQGRRGPVGPP---GAPGRDGSKGERGAPGPRGSPGPPG 333
                G  G VG P   G PG+DG +GE+GA G  GSPGP G
Sbjct: 931 -----GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 967



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 57/156 (36%), Positives = 69/156 (44%), Gaps = 50/156 (32%)

Query: 229 LGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP------GMPGPPGQPGPR 282
           +G +  G+K    +  LPGPPG  G +G  G PG  G PG P      G  GPPG PGP 
Sbjct: 521 IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPP 580

Query: 283 GSMGPMG----------------------------------PSPDLSHIKQGRR---GPV 305
           G +G  G                                  P P      QG +   GP 
Sbjct: 581 GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640

Query: 306 GPPGAPG----RDGSKGERGAPGPR---GSPGPPGS 334
           GPPG PG    ++G KGE+GAPGPR   G+PGPPG+
Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 46/93 (49%), Positives = 49/93 (52%), Gaps = 14/93 (15%)

Query: 247 GPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
           GPPG+PG        GPPG PGP G  G PG+PG  G PG  G  GP GP         G
Sbjct: 702 GPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGP--------PG 753

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           + GP GPPG PG  G  GERG  G  G PG  G
Sbjct: 754 KDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG 786



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 45/89 (50%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI--KQGRRGP 304
           GPPGL G +G  G  GP G PG  G+ GPPG PG  G  GP G SP L       G+ GP
Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP-GGSPGLPGEIGFPGKPGP 745

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP G PG+DG  G  G PG +G PG  G
Sbjct: 746 PGPTGPPGKDGPNGPPGPPGTKGEPGERG 774



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/109 (42%), Positives = 55/109 (50%), Gaps = 9/109 (8%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQG-------PPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285
           + GD+         GPPGLPG           PG  GPKG  G PG+PG PG  G  G +
Sbjct: 832 LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGEL 891

Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           GP GP+       +G+ G  G PGA G  G+ G  GAPGP G PG  G+
Sbjct: 892 GPQGPTGPPG--AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 938



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/93 (48%), Positives = 51/93 (54%), Gaps = 4/93 (4%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI-KQGRRG 303
            +PG PG  G +G  G  GP G PG PG+ GP G  G RG+ G +G   D  H    G  G
Sbjct: 1136 VPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMG 1195

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333
            P G PG PG DG  G  G PG +GSP   GPPG
Sbjct: 1196 PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 1228



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 44/93 (47%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG PG  G PG  GP G PG PG  G  G  GP G  G  G   D      G RG +
Sbjct: 1499 PGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEM 1558

Query: 306  GPPGAPGRDGSKGER-----GAPGPRGSPGPPG 333
            GPPG PG+ G  G       G PGP+G  GP G
Sbjct: 1559 GPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAG 1591



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 48/110 (43%), Positives = 57/110 (51%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM-------------PGPPGQ---PGPRGSMGPMG 289
           PGP G+ G QG  G  GP G PG PG              PGP G    PGP G+ GP+G
Sbjct: 622 PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIG 681

Query: 290 PS-----PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           P      P L  ++ G++G +GPPG PG  G +G  G PG  G PGP GS
Sbjct: 682 PEGRDGPPGLQGLR-GKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGS 730



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 45/95 (47%), Positives = 50/95 (52%), Gaps = 14/95 (14%)

Query: 246  PGPPGLPG------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
            PGPPGLPG       +G PG PG +G+ G  G  GPPG PGP G  GP G         Q
Sbjct: 1119 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG--------SQ 1170

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G RG  G  G  G  G  G  G  GP G+PGPPG+
Sbjct: 1171 GERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 1205



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 43/88 (48%), Positives = 49/88 (55%), Gaps = 5/88 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG PG  G +GPPG PG KG PG  G+PG PG+PG +G  G  G   D     +G  G  
Sbjct: 1356 PGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGD-----KGPPGGK 1410

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG PG  G KG  G  GP+G PG  G
Sbjct: 1411 GQPGDPGIPGHKGHTGLMGPQGLPGENG 1438



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 44/87 (50%), Positives = 50/87 (57%), Gaps = 4/87 (4%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G  G  GP G PGPKG  G     GP G PGP+G  G +G  P     ++G +G +G
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIG---AIGPVGAPGPKGEKGDVGIGP-FGQGEKGEKGSLG 536

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG PGRDGSKG RG PG  G PG PG
Sbjct: 537 LPGPPGRDGSKGMRGEPGELGEPGLPG 563



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/87 (50%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PG  G QG PG PG +G  G  G  GPPG  G RG  G MGP P +  +  G +GP G
Sbjct: 660 GAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGP-PGIPGL-LGLQGPPG 717

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PPG PG  G  G  G PG  G PG PG
Sbjct: 718 PPGVPGPPGPGGSPGLPGEIGFPGKPG 744



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 45/108 (41%), Positives = 53/108 (49%), Gaps = 14/108 (12%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSM 285
           G   L      PG PG PG  GPPG  GP G PG PG  G PG+         PG RG +
Sbjct: 729 GSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEI 788

Query: 286 GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G +      + G +G  G PGAPG  G +GE+G  G +G  G PG
Sbjct: 789 GEQGLAG-----RPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 831



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/134 (38%), Positives = 57/134 (42%), Gaps = 33/134 (24%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            I GDK        PG PG+PG +G  G  GP+G PG  G  GPPG PG  G  G  G SP
Sbjct: 1400 IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESP 1459

Query: 293  DLSHIK------------------------------QGRRGPVGPP---GAPGRDGSKGE 319
             +  ++                              QGR GP GPP   G PGR G  GE
Sbjct: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 1519

Query: 320  RGAPGPRGSPGPPG 333
             G PG  G  GP G
Sbjct: 1520 PGRPGQGGLEGPSG 1533



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 50/130 (38%), Positives = 56/130 (43%), Gaps = 31/130 (23%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGP------------------------KGSPGFP 270
            GDK +       G  G  G  GPPG PGP                        +G PG P
Sbjct: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191

Query: 271  GMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGP---PGAPGRDGSKGERGAP 323
            G  GPPG PGP G+ G  G    P    S  K+G  GP GP   PG PG +G +G  G P
Sbjct: 1192 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 1251

Query: 324  GPRGSPGPPG 333
            GP G PG  G
Sbjct: 1252 GPPGEPGKAG 1261



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/99 (42%), Positives = 51/99 (51%), Gaps = 10/99 (10%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---------PSPDLS 295
           LPG PG PG +G  G  G KG  G PG+ G  G+ G  G  GP G         P P + 
Sbjct: 805 LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP 864

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +QG +G  G PG PG  G +G  G  GP+G  GPPG+
Sbjct: 865 G-EQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 902



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 42/86 (48%), Positives = 47/86 (54%), Gaps = 3/86 (3%)

Query: 248  PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGP 307
            P  +   QG PG PGP G  G PG  GP G+PG  G  G  GPS  +    +G RG  G 
Sbjct: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG--PKGERGAKGD 1546

Query: 308  PGAPGRDGSKGERGAPGPRGSPGPPG 333
            PGAPG  G +GE G PG  G PG PG
Sbjct: 1547 PGAPG-VGLRGEMGPPGIPGQPGEPG 1571



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/97 (48%), Positives = 51/97 (52%), Gaps = 15/97 (15%)

Query: 240 ASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           A N   PG  G PG  GPPGS   PG +G+PG  G  G  G  G  GS GP+GP      
Sbjct: 915 AGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP------ 968

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                RG  G PG PG  G KG+ G PG RGSPG PG
Sbjct: 969 -----RGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPG 999



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 47/100 (47%), Positives = 54/100 (54%), Gaps = 3/100 (3%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD 293
           G+  +A    LPGP G  G  GP G+PGPKG  G  G+ GP GQ G +G  G +G P P 
Sbjct: 484 GEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGI-GPFGQ-GEKGEKGSLGLPGPP 541

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                +G RG  G  G PG  G  G RG  GP G PGPPG
Sbjct: 542 GRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPG 581



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 44/108 (40%), Positives = 51/108 (47%), Gaps = 19/108 (17%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--------------PSP 292
           GPPG  G  GPPG PG KG PG  G  G PG+PG RG +G  G               +P
Sbjct: 750 GPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 809

Query: 293 DLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSF 335
               ++     QG +G +G PG  G  G KGE G  GP G PG    F
Sbjct: 810 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 857



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 46/106 (43%), Positives = 51/106 (48%), Gaps = 7/106 (6%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            G+K  A     PGP G  G  G PG PGP  KG  G PG+ G PG PGP G+    G   
Sbjct: 952  GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAP-----GPRGSPGPPG 333
               +   G +   G  GAPG  GS G RG P     GP G  GPPG
Sbjct: 1012 GSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPG 1057



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 48/124 (38%), Positives = 57/124 (45%), Gaps = 31/124 (25%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGM---------------------PGPPGQPGPRGS 284
            PGP G  G  G PG+PG +G PG PG+                     PGPPG PG  G 
Sbjct: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF 1130

Query: 285  MGPMG----PSPDLSHIKQGRRGPVG---PPGAPGRDGSKGERGAPGP---RGSPGPPGS 334
             G  G    P  + +  K+G  GP G   PPG  G  GS+GERGA G    +G  G PG 
Sbjct: 1131 KGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGV 1190

Query: 335  FDFL 338
              F+
Sbjct: 1191 PGFM 1194



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 54/141 (38%), Positives = 59/141 (41%), Gaps = 38/141 (26%)

Query: 245  LPGPPGL-----PGGQGPPGSPGP--------------------------KGSPGFPGMP 273
            LPGPPG      PG +G PG PGP                          +G+PG PG P
Sbjct: 977  LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036

Query: 274  GPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332
            G  G PG  G  GP GPS P       G RG  G PG  G  G  G  G PG RG PG P
Sbjct: 1037 GSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKP 1095

Query: 333  GSFDFLL-----LMLADIRND 348
            G    L      L+  D+ ND
Sbjct: 1096 GLSSLLSPGDINLLAKDVCND 1116



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 41/90 (45%), Positives = 47/90 (52%), Gaps = 8/90 (8%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPS 291
            G+K +     +PG PG PG +G  G PG KG  G PG  G PG    PG +G  G MGP 
Sbjct: 1372 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 1431

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321
                    G  GPVGPPG PG+ G  G RG
Sbjct: 1432 G-----LPGENGPVGPPGPPGQPGFPGLRG 1456



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 45/108 (41%), Positives = 55/108 (50%), Gaps = 11/108 (10%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG--QPGPRGSMG------ 286
            GDK    +  LPG PG  G  G  G+PG  G  G PG PG      PG    +       
Sbjct: 1057 GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCND 1116

Query: 287  -PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P GP P L  +  G +G  G PG PGR+G++G++G  GP G PGPPG
Sbjct: 1117 CPPGP-PGLPGL-PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 42/108 (38%), Positives = 46/108 (42%), Gaps = 20/108 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  G PG +G PG  G +G  G  G  G PG  GPRG  G  G        K G  G  
Sbjct: 933  PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 992

Query: 306  GPPGAPGRDGS--------------------KGERGAPGPRGSPGPPG 333
            G PG PG  G+                    KG+RGAPG  GSPG  G
Sbjct: 993  GSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG 1040



 Score = 63.2 bits (152), Expect = 4e-10
 Identities = 37/92 (40%), Positives = 43/92 (46%), Gaps = 23/92 (25%)

Query: 247  GPPGLPGGQGPPGSPGP--KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            GP G  G +G PG+PG   +G  G PG+PG PG+PG               + K G    
Sbjct: 1536 GPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG---------------YAKDGL--- 1577

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
               PG PG  G  G  G PG  G PGPPG  D
Sbjct: 1578 ---PGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 24/41 (58%), Positives = 24/41 (58%), Gaps = 5/41 (12%)

Query: 246  PGPPG-----LPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP 281
            PG PG     LPG  GP G  GP G PG PG PGPPGQ  P
Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607



 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 29/62 (46%), Positives = 31/62 (50%), Gaps = 16/62 (25%)

Query: 246  PGPPG--LPGGQGPPGSPGPKGSPGF-----PGMPGP---------PGQPGPRGSMGPMG 289
            PG PG  L G  GPPG PG  G PG+     PG+PGP         PG PGP G  G   
Sbjct: 1547 PGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCD 1606

Query: 290  PS 291
            PS
Sbjct: 1607 PS 1608



 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 24/45 (53%), Positives = 26/45 (57%), Gaps = 2/45 (4%)

Query: 245  LPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGP 287
            +PG PG PG    G PG PGP+G  G  G PG PG PGP G   P
Sbjct: 1563 IPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDP 1607



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 14/31 (45%), Positives = 15/31 (48%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG 277
            G PGLPG  GPPG   P     F  +   PG
Sbjct: 1591 GHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG QGP G PGPKG PG PG  G PG PG RG +G            QG+ GP 
Sbjct: 787 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 835

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G+ GE G  G RG PGPPG
Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPG 863



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PG PG PG +GP G  GPKG+PG   FPG PGPPG+ GPRG  G            +G R
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1207

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G  G PG PG  G  GE G PGP G  GP GS
Sbjct: 1208 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%)

Query: 234  TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287
            TGD     N   PGP G PG  GPPG  GP      KG  G  G PG PG PGP G  GP
Sbjct: 1171 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1227

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP         G+RGP G PG+ GR G KG +G PG  G+PG  G
Sbjct: 1228 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G+      T  PGPPG+ G QG  G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 824 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 875

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              K+G +G  GPPGAPG+DG  G RG PG RG PG  G
Sbjct: 876 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%)

Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278
           G K     T  PGPPGL         PG  G PG  GPKGS GFPG PG  G+       
Sbjct: 686 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 745

Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326
              GPRG  GP GP     P  +  K G +      GP GPPG  G  G +G  G PGP+
Sbjct: 746 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 805

Query: 327 GSPGPPG 333
           G PGPPG
Sbjct: 806 GPPGPPG 812



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301
            PGP G PG +G  GS GP G PG PG  GPPG  G +   G  GP+GP+  D      G 
Sbjct: 925  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 984

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
             GP GPPG  G DG KGE G PG +G+         PGPPG
Sbjct: 985  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GP GLPG  GP G  GPKG PG PG PG  G  GP+G  G +GP        QG  GP G
Sbjct: 512 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 563

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG  G  G +GA GP G  GP G
Sbjct: 564 QQGTPGTQGLPGPQGAIGPHGEKGPQG 590



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305
            GPPG PG QGPPG+ G KG PG  G  GP G+ G +G +G  GP+ P     + G +G V
Sbjct: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G  G+KGE G PGP G  GP G
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G  G  G +G PG PG KG  GF G+PG PG+ G RG  G  G P P     ++G  G +
Sbjct: 452 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 511

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G PG  G +G  G  GP G PGPPG
Sbjct: 512 GPRGLPGESGPRGLLGPKGPPGIPGPPG 539



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%)

Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297
           +PGPPG+    G QGP GS GP+G PG PG  G PG    PGP+G++GP G   P     
Sbjct: 534 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  GPPG PG++G  G +G  GP G  GP G
Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 629



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PG PG +G  G  GPKGS G  G PGPPGQ G  G+ G  GP   +     G +GP 
Sbjct: 532 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 589

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG  GS G  G PG  G PG  G+
Sbjct: 590 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    +LG    G+K     +  PG  G PG +GP G  G KG  G PG PGPPG  GP 
Sbjct: 1114 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1171

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GP G    +     G  GP G  G  G+DG+KG+RG  G  G PG PG
Sbjct: 1172 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285
            GPPGLPG +G  G+ G KG PG  G+ GPPG+         PGP+GS             
Sbjct: 1307 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1366

Query: 286  GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+GP   P L     G  GP G  GA G  G KGE+G  GP G PGPPG
Sbjct: 1367 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299
           PG PG+PG  GPPG PG +G PG  G  GP G       PGPRG  G  G      H  +
Sbjct: 592 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 651

Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                           G RG VG PG+ G DG +G +G  GP G PGPPG
Sbjct: 652 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 701



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK    +    G  G  G  GPPG PGP G  G PG  G  G+PG RG  G  G   D 
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 295  -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             +    G  GP+G  G PG  G KGE G  GP G PGPPG
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1097



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297
           GPPG PG  G PG PG +G  GF G  GPPG PG   P+G+ G  GP  +  H       
Sbjct: 806 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 865

Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323
                     K+G +G  GPPGAPG+DG  G RG                         P
Sbjct: 866 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 925

Query: 324 GPRGSPGPPGS 334
           GP GSPG  G+
Sbjct: 926 GPAGSPGERGA 936



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%)

Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296
           +PG PG+ G +G       PG  G +G  G  G+PGPPG+ G RG  G +GP   P  S 
Sbjct: 462 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 521

Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333
             +G  GP GPPG P      G DG +G +G+ GP+G PGPPG
Sbjct: 522 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 563



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%)

Query: 246 PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           PGPPG PG  GP          G PG  G PG  G  GP G PGP GS G  G +     
Sbjct: 883 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 937

Query: 297 IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333
              G  GP+GPPG PG     G+ GE+G PG +G  GP G
Sbjct: 938 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 974



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G  GPPG  G  G  G PG+ G PG  GPRG  G  G S      + G  GP G
Sbjct: 1112 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1166

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P G  G DG KG  G  G  G PGPPG
Sbjct: 1167 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1193



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298
            PG  G  G  GP G PGP G  G PG  G  G+PG  G  GP GP   P L  ++     
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320

Query: 299  ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               +G  G +G  G PG  G KG+RG PGP+GSPG  G
Sbjct: 1321 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1358



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301
            PGPPG  G  GP G+ GP+G PG  G  GPP   G+PG  GS G  G P       ++G 
Sbjct: 1093 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1152

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG PG  G KG  G  GP+G+PGP G
Sbjct: 1153 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1184



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G QG PG  G KG  G  G  GPPG PGPRG  GP            G  GP G
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1112

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPG  G  G  GE+G PG  GSPG  G
Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQG 1139



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301
           PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G  G  G    P        +G 
Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 302 RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334
            GP GPPG  G  G +G  G+ GP       G  GPPG+
Sbjct: 919 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 957



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289
            G K    N    GPPG PG  GP G PG  G+ G PG  GP G  G +G  G  G     
Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066

Query: 290  --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333
                    P P     + G  GP+GPPG PG  G  G  GA GP+G P      GPPG
Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%)

Query: 247  GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299
            GPPG  G +GP GSPG       KG+ G PG  G PG+ GP G  GP G P PD      
Sbjct: 1226 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1279

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G RG  G  G  GR G+ G+ G PGP G PG PG
Sbjct: 1280 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PG  GLPG QG   P G  GP+G PG PGMPG  G PG  G  GP G   +     QG  
Sbjct: 568 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 622

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           GP GP G PG  G KG  G  G +G  G  G   F
Sbjct: 623 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292
           LPGPPG  G +G  G  GP+G    PG  GP            PG PG RG  GP GP  
Sbjct: 495 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 549

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 +G  GP G PG PG+ G+ G +G PGP+G+ GP G
Sbjct: 550 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 584



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287
           +G+K     +   GP G  G  GP G  GP+G+ G  G        GP G PG RG  GP
Sbjct: 736 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 795

Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333
            GP+        G  GP GPPG PG+D      G +GE G  G  G PGPPG
Sbjct: 796 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 839



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           + G +  A  T   G  G PG  GPPG    PG  G  G  G PGPPG PG  G  G  G
Sbjct: 840 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 899

Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  P        +G  GP GPPG  G  G +G  G+ GP G PG PG
Sbjct: 900 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 950



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297
            PGP GL G  GP G  G  G  G  G PGPPG     GP G+ GP GP   + ++     
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125

Query: 298  -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 + G  G  G PG  G  G +GE+G  G  G PGPPG
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1166



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288
           L GPPG+ G  GP G PG +G PG  G+PG  G PGP G+               GP+  
Sbjct: 323 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 382

Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328
                             GP   + +   GR GP+G PG+PG  G  G+ G  GPRG   
Sbjct: 383 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440

Query: 329 -PGPPG 333
             GPPG
Sbjct: 441 LTGPPG 446



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300
            GP G  G QGP G PGP G PG  G  G       PGQ G +G+ G  GP         G
Sbjct: 971  GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1022

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP+GP G PG  G+ GE GA GP+G  G  G
Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300
            LPGP G PG  G  G  G  G PG  G  G  G+ GP G  GP+GP   P  +    + G
Sbjct: 984  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1043

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             RGP G  GA G +G++G  G PGP G  G PG
Sbjct: 1044 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1076



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G+PG +G  G  GPKG  G  G PGPPG  G +G +G  G  P     +QG +G +G
Sbjct: 671 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 728

Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333
            PG PG  G KG R   G  GPRG  GP G
Sbjct: 729 FPGFPGASGEKGARGLSGKSGPRGERGPTG 758



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GPPG  G  G PG  G  GSPG  G  G  G  GPRG  G  GP       K GRRG 
Sbjct: 399 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 453

Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333
            G  GA                  PG  G KG RG  G +G PGPPG
Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            LPGP G PG +G  G PG  G  G  G PG PG  GP+G+ G  GP        +G +G 
Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1401

Query: 305  VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342
             GPPG PG  G            K  R   G R           G+PG PG  + +   L
Sbjct: 1402 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1461

Query: 343  ADIRNDITELQ 353
              +R +I +++
Sbjct: 1462 DSLREEIEQMR 1472



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289
           K + G + L  +    G  G PG +G  G  G +G  G PG  G  G  GP+G  GP G 
Sbjct: 637 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 696

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           P P     ++G+ G  G PG PGR G KG  G PG  G+ G  G+
Sbjct: 697 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 741



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 41/91 (45%), Positives = 44/91 (48%), Gaps = 15/91 (16%)

Query: 248 PPGLPGGQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           PP      GP G  G KG P    PGM   GPPG  GP G +GP G         QG  G
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPG 334

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PVG PG     G  G  G PG  G+PGPPG+
Sbjct: 335 PVGDPG---ERGPPGRAGLPGSDGAPGPPGT 362


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG QGP G PGPKG PG PG  G PG PG RG +G            QG+ GP 
Sbjct: 766 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 814

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G+ GE G  G RG PGPPG
Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPG 842



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PG PG PG +GP G  GPKG+PG   FPG PGPPG+ GPRG  G            +G R
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1186

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G  G PG PG  G  GE G PGP G  GP GS
Sbjct: 1187 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%)

Query: 234  TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287
            TGD     N   PGP G PG  GPPG  GP      KG  G  G PG PG PGP G  GP
Sbjct: 1150 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1206

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP         G+RGP G PG+ GR G KG +G PG  G+PG  G
Sbjct: 1207 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G+      T  PGPPG+ G QG  G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 854

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              K+G +G  GPPGAPG+DG  G RG PG RG PG  G
Sbjct: 855 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%)

Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278
           G K     T  PGPPGL         PG  G PG  GPKGS GFPG PG  G+       
Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724

Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326
              GPRG  GP GP     P  +  K G +      GP GPPG  G  G +G  G PGP+
Sbjct: 725 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 784

Query: 327 GSPGPPG 333
           G PGPPG
Sbjct: 785 GPPGPPG 791



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301
            PGP G PG +G  GS GP G PG PG  GPPG  G +   G  GP+GP+  D      G 
Sbjct: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 963

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
             GP GPPG  G DG KGE G PG +G+         PGPPG
Sbjct: 964  PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GP GLPG  GP G  GPKG PG PG PG  G  GP+G  G +GP        QG  GP G
Sbjct: 491 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 542

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG  G  G +GA GP G  GP G
Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGPQG 569



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305
            GPPG PG QGPPG+ G KG PG  G  GP G+ G +G +G  GP+ P     + G +G V
Sbjct: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G  G+KGE G PGP G  GP G
Sbjct: 983  GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G  G  G +G PG PG KG  GF G+PG PG+ G RG  G  G P P     ++G  G +
Sbjct: 431 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 490

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G PG  G +G  G  GP G PGPPG
Sbjct: 491 GPRGLPGESGPRGLLGPKGPPGIPGPPG 518



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%)

Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297
           +PGPPG+    G QGP GS GP+G PG PG  G PG    PGP+G++GP G   P     
Sbjct: 513 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  GPPG PG++G  G +G  GP G  GP G
Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 608



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PG PG +G  G  GPKGS G  G PGPPGQ G  G+ G  GP   +     G +GP 
Sbjct: 511 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 568

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG  GS G  G PG  G PG  G+
Sbjct: 569 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 597



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    +LG    G+K     +  PG  G PG +GP G  G KG  G PG PGPPG  GP 
Sbjct: 1093 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1150

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GP G    +     G  GP G  G  G+DG+KG+RG  G  G PG PG
Sbjct: 1151 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1199



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285
            GPPGLPG +G  G+ G KG PG  G+ GPPG+         PGP+GS             
Sbjct: 1286 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1345

Query: 286  GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+GP   P L     G  GP G  GA G  G KGE+G  GP G PGPPG
Sbjct: 1346 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299
           PG PG+PG  GPPG PG +G PG  G  GP G       PGPRG  G  G      H  +
Sbjct: 571 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 630

Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                           G RG VG PG+ G DG +G +G  GP G PGPPG
Sbjct: 631 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK    +    G  G  G  GPPG PGP G  G PG  G  G+PG RG  G  G   D 
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 295  -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             +    G  GP+G  G PG  G KGE G  GP G PGPPG
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1076



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297
           GPPG PG  G PG PG +G  GF G  GPPG PG   P+G+ G  GP  +  H       
Sbjct: 785 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 844

Query: 298 ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323
                     K+G +G  GPPGAPG+DG  G RG                         P
Sbjct: 845 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904

Query: 324 GPRGSPGPPGS 334
           GP GSPG  G+
Sbjct: 905 GPAGSPGERGA 915



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%)

Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296
           +PG PG+ G +G       PG  G +G  G  G+PGPPG+ G RG  G +GP   P  S 
Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 500

Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333
             +G  GP GPPG P      G DG +G +G+ GP+G PGPPG
Sbjct: 501 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%)

Query: 246 PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           PGPPG PG  GP          G PG  G PG  G  GP G PGP GS G  G +     
Sbjct: 862 PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 916

Query: 297 IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333
              G  GP+GPPG PG     G+ GE+G PG +G  GP G
Sbjct: 917 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G  GPPG  G  G  G PG+ G PG  GPRG  G  G S      + G  GP G
Sbjct: 1091 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1145

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P G  G DG KG  G  G  G PGPPG
Sbjct: 1146 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1172



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298
            PG  G  G  GP G PGP G  G PG  G  G+PG  G  GP GP   P L  ++     
Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299

Query: 299  ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               +G  G +G  G PG  G KG+RG PGP+GSPG  G
Sbjct: 1300 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1337



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301
            PGPPG  G  GP G+ GP+G PG  G  GPP   G+PG  GS G  G P       ++G 
Sbjct: 1072 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1131

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG PG  G KG  G  GP+G+PGP G
Sbjct: 1132 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1163



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G QG PG  G KG  G  G  GPPG PGPRG  GP            G  GP G
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1091

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPG  G  G  GE+G PG  GSPG  G
Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQG 1118



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301
           PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G  G  G    P        +G 
Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 302 RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334
            GP GPPG  G  G +G  G+ GP       G  GPPG+
Sbjct: 898 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289
            G K    N    GPPG PG  GP G PG  G+ G PG  GP G  G +G  G  G     
Sbjct: 986  GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045

Query: 290  --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333
                    P P     + G  GP+GPPG PG  G  G  GA GP+G P      GPPG
Sbjct: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%)

Query: 247  GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299
            GPPG  G +GP GSPG       KG+ G PG  G PG+ GP G  GP G P PD      
Sbjct: 1205 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1258

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G RG  G  G  GR G+ G+ G PGP G PG PG
Sbjct: 1259 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PG  GLPG QG   P G  GP+G PG PGMPG  G PG  G  GP G   +     QG  
Sbjct: 547 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 601

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           GP GP G PG  G KG  G  G +G  G  G   F
Sbjct: 602 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292
           LPGPPG  G +G  G  GP+G    PG  GP            PG PG RG  GP GP  
Sbjct: 474 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 528

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 +G  GP G PG PG+ G+ G +G PGP+G+ GP G
Sbjct: 529 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287
           +G+K     +   GP G  G  GP G  GP+G+ G  G        GP G PG RG  GP
Sbjct: 715 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 774

Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333
            GP+        G  GP GPPG PG+D      G +GE G  G  G PGPPG
Sbjct: 775 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 818



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           + G +  A  T   G  G PG  GPPG    PG  G  G  G PGPPG PG  G  G  G
Sbjct: 819 VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878

Query: 290 -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  P        +G  GP GPPG  G  G +G  G+ GP G PG PG
Sbjct: 879 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 929



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297
            PGP GL G  GP G  G  G  G  G PGPPG     GP G+ GP GP   + ++     
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104

Query: 298  -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 + G  G  G PG  G  G +GE+G  G  G PGPPG
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1145



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288
           L GPPG+ G  GP G PG +G PG  G+PG  G PGP G+               GP+  
Sbjct: 302 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 361

Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328
                             GP   + +   GR GP+G PG+PG  G  G+ G  GPRG   
Sbjct: 362 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419

Query: 329 -PGPPG 333
             GPPG
Sbjct: 420 LTGPPG 425



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300
            GP G  G QGP G PGP G PG  G  G       PGQ G +G+ G  GP         G
Sbjct: 950  GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1001

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP+GP G PG  G+ GE GA GP+G  G  G
Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1034



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300
            LPGP G PG  G  G  G  G PG  G  G  G+ GP G  GP+GP   P  +    + G
Sbjct: 963  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             RGP G  GA G +G++G  G PGP G  G PG
Sbjct: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1055



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G+PG +G  G  GPKG  G  G PGPPG  G +G +G  G  P     +QG +G +G
Sbjct: 650 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 707

Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333
            PG PG  G KG R   G  GPRG  GP G
Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTG 737



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GPPG  G  G PG  G  GSPG  G  G  G  GPRG  G  GP       K GRRG 
Sbjct: 378 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 432

Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333
            G  GA                  PG  G KG RG  G +G PGPPG
Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            LPGP G PG +G  G PG  G  G  G PG PG  GP+G+ G  GP        +G +G 
Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1380

Query: 305  VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342
             GPPG PG  G            K  R   G R           G+PG PG  + +   L
Sbjct: 1381 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1440

Query: 343  ADIRNDITELQ 353
              +R +I +++
Sbjct: 1441 DSLREEIEQMR 1451



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289
           K + G + L  +    G  G PG +G  G  G +G  G PG  G  G  GP+G  GP G 
Sbjct: 616 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 675

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           P P     ++G+ G  G PG PGR G KG  G PG  G+ G  G+
Sbjct: 676 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 720



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 40/90 (44%), Positives = 43/90 (47%), Gaps = 15/90 (16%)

Query: 249 PGLPGGQGPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           P      GP G  G KG P    PGM   GPPG  GP G +GP G         QG  GP
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPGP 314

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           VG PG     G  G  G PG  G+PGPPG+
Sbjct: 315 VGDPG---ERGPPGRAGLPGSDGAPGPPGT 341



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 45/125 (36%), Positives = 49/125 (39%), Gaps = 40/125 (32%)

Query: 247 GPPGLPGGQGPP----------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           GP GL G +G P          G PGP+G  G  G PG  G PGP G  G  GP P  + 
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAG 328

Query: 297 IKQGRRGPVGPPGA----PGRDGSKGE------------------------RGAPGPRGS 328
           +  G  G  GPPG     P R GS G                         RG PGP G 
Sbjct: 329 L-PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 387

Query: 329 PGPPG 333
            G PG
Sbjct: 388 TGRPG 392


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/88 (54%), Positives = 51/88 (57%), Gaps = 11/88 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG QGP G PGPKG PG PG  G PG PG RG +G            QG+ GP 
Sbjct: 873 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVG-----------FQGKTGPP 921

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GPPG  G  G+ GE G  G RG PGPPG
Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPG 949



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 48/92 (52%), Positives = 52/92 (56%), Gaps = 14/92 (15%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            PG PG PG +GP G  GPKG+PG   FPG PGPPG+ GPRG  G            +G R
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA-----------KGDR 1293

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G  G PG PG  G  GE G PGP G  GP GS
Sbjct: 1294 GEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 51/106 (48%), Positives = 55/106 (51%), Gaps = 17/106 (16%)

Query: 234  TGDKVLASNTYLPGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGP 287
            TGD     N   PGP G PG  GPPG  GP      KG  G  G PG PG PGP G  GP
Sbjct: 1257 TGDDGPKGN---PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1313

Query: 288  MGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP         G+RGP G PG+ GR G KG +G PG  G+PG  G
Sbjct: 1314 PGP--------LGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 47/99 (47%), Positives = 54/99 (54%), Gaps = 11/99 (11%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G+      T  PGPPG+ G QG  G  GP G  G PG PGPPG+ G  G+ G        
Sbjct: 910 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAG-------- 961

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              K+G +G  GPPGAPG+DG  G RG PG RG PG  G
Sbjct: 962 ---KEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 56/127 (44%), Positives = 61/127 (48%), Gaps = 28/127 (22%)

Query: 235 GDKVLASNTYLPGPPGL---------PGGQGPPGSPGPKGSPGFPGMPGPPGQ------- 278
           G K     T  PGPPGL         PG  G PG  GPKGS GFPG PG  G+       
Sbjct: 772 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 831

Query: 279 --PGPRGSMGPMGP----SPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPR 326
              GPRG  GP GP     P  +  K G +      GP GPPG  G  G +G  G PGP+
Sbjct: 832 GKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK 891

Query: 327 GSPGPPG 333
           G PGPPG
Sbjct: 892 GPPGPPG 898



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR---GSMGPMGPS-PDLSHIKQGR 301
            PGP G PG +G  GS GP G PG PG  GPPG  G +   G  GP+GP+  D      G 
Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGL 1070

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGS---------PGPPG 333
             GP GPPG  G DG KGE G PG +G+         PGPPG
Sbjct: 1071 PGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 44/87 (50%), Positives = 47/87 (54%), Gaps = 8/87 (9%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GP GLPG  GP G  GPKG PG PG PG  G  GP+G  G +GP        QG  GP G
Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGP--------QGEPGPPG 649

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG  G  G +GA GP G  GP G
Sbjct: 650 QQGTPGTQGLPGPQGAIGPHGEKGPQG 676



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 45/88 (51%), Positives = 53/88 (60%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-PDLSHIKQGRRGPV 305
            GPPG PG QGPPG+ G KG PG  G  GP G+ G +G +G  GP+ P     + G +G V
Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG  G  G+KGE G PGP G  GP G
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 42/88 (47%), Positives = 49/88 (55%), Gaps = 1/88 (1%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
           G  G  G +G PG PG KG  GF G+PG PG+ G RG  G  G P P     ++G  G +
Sbjct: 538 GRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEI 597

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G PG  G +G  G  GP G PGPPG
Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPG 625



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 46/96 (47%), Positives = 55/96 (57%), Gaps = 7/96 (7%)

Query: 245 LPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMG-PSPDLSHI 297
           +PGPPG+    G QGP GS GP+G PG PG  G PG    PGP+G++GP G   P     
Sbjct: 620 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  GPPG PG++G  G +G  GP G  GP G
Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLG 715



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 44/89 (49%), Positives = 49/89 (55%), Gaps = 2/89 (2%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PG PG +G  G  GPKGS G  G PGPPGQ G  G+ G  GP   +     G +GP 
Sbjct: 618 PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG--PHGEKGPQ 675

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG  GS G  G PG  G PG  G+
Sbjct: 676 GKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 48/111 (43%), Positives = 56/111 (50%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    +LG    G+K     +  PG  G PG +GP G  G KG  G PG PGPPG  GP 
Sbjct: 1200 PGGVGNLGP--PGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPT 1257

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  GP G    +     G  GP G  G  G+DG+KG+RG  G  G PG PG
Sbjct: 1258 GDDGPKGNPGPVGF--PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1306



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGS------------M 285
            GPPGLPG +G  G+ G KG PG  G+ GPPG+         PGP+GS             
Sbjct: 1393 GPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGAS 1452

Query: 286  GPMGPS--PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+GP   P L     G  GP G  GA G  G KGE+G  GP G PGPPG
Sbjct: 1453 GPIGPGGPPGL----PGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQ 299
           PG PG+PG  GPPG PG +G PG  G  GP G       PGPRG  G  G      H  +
Sbjct: 678 PGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGE 737

Query: 300 ----------------GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                           G RG VG PG+ G DG +G +G  GP G PGPPG
Sbjct: 738 KGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPG 787



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 46/100 (46%), Positives = 50/100 (50%), Gaps = 1/100 (1%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK    +    G  G  G  GPPG PGP G  G PG  G  G+PG RG  G  G   D 
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 295  -SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             +    G  GP+G  G PG  G KGE G  GP G PGPPG
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPG 1183



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 50/131 (38%), Positives = 58/131 (44%), Gaps = 43/131 (32%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG---PRGSMGPMGPSPDLSHI------ 297
            GPPG PG  G PG PG +G  GF G  GPPG PG   P+G+ G  GP  +  H       
Sbjct: 892  GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 951

Query: 298  ----------KQGRRGPVGPPGAPGRDGSKGERG------------------------AP 323
                      K+G +G  GPPGAPG+DG  G RG                         P
Sbjct: 952  GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011

Query: 324  GPRGSPGPPGS 334
            GP GSPG  G+
Sbjct: 1012 GPAGSPGERGA 1022



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 46/103 (44%), Positives = 58/103 (56%), Gaps = 15/103 (14%)

Query: 245 LPGPPGLPGGQG------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS--PDLSH 296
           +PG PG+ G +G       PG  G +G  G  G+PGPPG+ G RG  G +GP   P  S 
Sbjct: 548 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESG 607

Query: 297 IKQGRRGPVGPPGAP------GRDGSKGERGAPGPRGSPGPPG 333
             +G  GP GPPG P      G DG +G +G+ GP+G PGPPG
Sbjct: 608 -PRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 649



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 45/100 (45%), Positives = 50/100 (50%), Gaps = 20/100 (20%)

Query: 246  PGPPGLPGGQGPP---------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            PGPPG PG  GP          G PG  G PG  G  GP G PGP GS G  G +     
Sbjct: 969  PGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA----- 1023

Query: 297  IKQGRRGPVGPPGAPGRD---GSKGERGAPGPRGSPGPPG 333
               G  GP+GPPG PG     G+ GE+G PG +G  GP G
Sbjct: 1024 ---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 1060



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 43/87 (49%), Positives = 45/87 (51%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G  GPPG  G  G  G PG+ G PG  GPRG  G  G S      + G  GP G
Sbjct: 1198 GPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESG-----QPGEPGPPG 1252

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P G  G DG KG  G  G  G PGPPG
Sbjct: 1253 PKGPTGDDGPKGNPGPVGFPGDPGPPG 1279



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 44/98 (44%), Positives = 51/98 (52%), Gaps = 10/98 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIK----- 298
            PG  G  G  GP G PGP G  G PG  G  G+PG  G  GP GP   P L  ++     
Sbjct: 1347 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1406

Query: 299  ---QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               +G  G +G  G PG  G KG+RG PGP+GSPG  G
Sbjct: 1407 KGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKG 1444



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 44/92 (47%), Positives = 52/92 (56%), Gaps = 4/92 (4%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMG-PSPDLSHIKQGR 301
            PGPPG  G  GP G+ GP+G PG  G  GPP   G+PG  GS G  G P       ++G 
Sbjct: 1179 PGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGE 1238

Query: 302  RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG PG  G KG  G  GP+G+PGP G
Sbjct: 1239 KGESGQPGEPGPPGPKGPTGDDGPKGNPGPVG 1270



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/87 (50%), Positives = 45/87 (51%), Gaps = 11/87 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG  G QG PG  G KG  G  G  GPPG PGPRG  GP            G  GP G
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGP-----------NGADGPQG 1198

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PPG  G  G  GE+G PG  GSPG  G
Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGIQG 1225



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 44/99 (44%), Positives = 52/99 (52%), Gaps = 10/99 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301
            PGPPG PG QG PG+ G +G+ G PG PG PG+ GP G  G  G    P        +G 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 302  RGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPGS 334
             GP GPPG  G  G +G  G+ GP       G  GPPG+
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 1043



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 48/118 (40%), Positives = 53/118 (44%), Gaps = 19/118 (16%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----- 289
            G K    N    GPPG PG  GP G PG  G+ G PG  GP G  G +G  G  G     
Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1152

Query: 290  --------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP------GPPG 333
                    P P     + G  GP+GPPG PG  G  G  GA GP+G P      GPPG
Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 46/94 (48%), Positives = 51/94 (54%), Gaps = 13/94 (13%)

Query: 247  GPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQ 299
            GPPG  G +GP GSPG       KG+ G PG  G PG+ GP G  GP G P PD      
Sbjct: 1312 GPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPD------ 1365

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G RG  G  G  GR G+ G+ G PGP G PG PG
Sbjct: 1366 GLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1399



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 8/95 (8%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PG  GLPG QG   P G  GP+G PG PGMPG  G PG  G  GP G   +     QG  
Sbjct: 654 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN-----QGPS 708

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           GP GP G PG  G KG  G  G +G  G  G   F
Sbjct: 709 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 44/101 (43%), Positives = 52/101 (51%), Gaps = 23/101 (22%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292
           LPGPPG  G +G  G  GP+G    PG  GP            PG PG RG  GP GP  
Sbjct: 581 LPGPPGEDGERGDDGEIGPRG---LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP-- 635

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 +G  GP G PG PG+ G+ G +G PGP+G+ GP G
Sbjct: 636 ------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 670



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 46/112 (41%), Positives = 54/112 (48%), Gaps = 20/112 (17%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGP 287
           +G+K     +   GP G  G  GP G  GP+G+ G  G        GP G PG RG  GP
Sbjct: 822 SGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGP 881

Query: 288 MGPSPDLSHIKQGRRGPVGPPGAPGRD------GSKGERGAPGPRGSPGPPG 333
            GP+        G  GP GPPG PG+D      G +GE G  G  G PGPPG
Sbjct: 882 QGPN--------GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPG 925



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 45/111 (40%), Positives = 50/111 (45%), Gaps = 10/111 (9%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
            + G +  A  T   G  G PG  GPPG    PG  G  G  G PGPPG PG  G  G  G
Sbjct: 926  VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 985

Query: 290  -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                   P        +G  GP GPPG  G  G +G  G+ GP G PG PG
Sbjct: 986  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPG 1036



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 42/101 (41%), Positives = 49/101 (48%), Gaps = 13/101 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---PGPRGSMGPMGPSPDLSHI----- 297
            PGP GL G  GP G  G  G  G  G PGPPG     GP G+ GP GP   + ++     
Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1211

Query: 298  -----KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 + G  G  G PG  G  G +GE+G  G  G PGPPG
Sbjct: 1212 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPG 1252



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 39/126 (30%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGS--------------MGPM-- 288
           L GPPG+ G  GP G PG +G PG  G+PG  G PGP G+               GP+  
Sbjct: 409 LIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVA 468

Query: 289 ------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS-- 328
                             GP   + +   GR GP+G PG+PG  G  G+ G  GPRG   
Sbjct: 469 AQEAQAQAILQQARLALRGPPGPMGY--TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526

Query: 329 -PGPPG 333
             GPPG
Sbjct: 527 LTGPPG 532



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 47/93 (50%), Gaps = 14/93 (15%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPMGPSPDLSHIKQG 300
            GP G  G QGP G PGP G PG  G  G       PGQ G +G+ G  GP         G
Sbjct: 1057 GPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGP--------PG 1108

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP+GP G PG  G+ GE GA GP+G  G  G
Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1141



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHI--KQG 300
            LPGP G PG  G  G  G  G PG  G  G  G+ GP G  GP+GP   P  +    + G
Sbjct: 1070 LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1129

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             RGP G  GA G +G++G  G PGP G  G PG
Sbjct: 1130 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPG 1162



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 42/90 (46%), Positives = 49/90 (54%), Gaps = 5/90 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G  G+PG +G  G  GPKG  G  G PGPPG  G +G +G  G  P     +QG +G +G
Sbjct: 757 GEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPG-RQGPKGSLG 814

Query: 307 PPGAPGRDGSKGER---GAPGPRGSPGPPG 333
            PG PG  G KG R   G  GPRG  GP G
Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTG 844



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 46/107 (42%), Positives = 47/107 (43%), Gaps = 23/107 (21%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GPPG  G  G PG  G  GSPG  G  G  G  GPRG  G  GP       K GRRG 
Sbjct: 485 LRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG-----KAGRRGR 539

Query: 305 VGPPGA------------------PGRDGSKGERGAPGPRGSPGPPG 333
            G  GA                  PG  G KG RG  G +G PGPPG
Sbjct: 540 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 45/131 (34%), Positives = 58/131 (44%), Gaps = 27/131 (20%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            LPGP G PG +G  G PG  G  G  G PG PG  GP+G+ G  GP        +G +G 
Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGG-----PKGEKGV 1487

Query: 305  VGPPGAPGRDG-----------SKGERGAPGPR-----------GSPGPPGSFDFLLLML 342
             GPPG PG  G            K  R   G R           G+PG PG  + +   L
Sbjct: 1488 QGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSL 1547

Query: 343  ADIRNDITELQ 353
              +R +I +++
Sbjct: 1548 DSLREEIEQMR 1558



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 41/105 (39%), Positives = 52/105 (49%), Gaps = 1/105 (0%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG- 289
           K + G + L  +    G  G PG +G  G  G +G  G PG  G  G  GP+G  GP G 
Sbjct: 723 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGD 782

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           P P     ++G+ G  G PG PGR G KG  G PG  G+ G  G+
Sbjct: 783 PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGA 827



 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 39/83 (46%), Positives = 42/83 (50%), Gaps = 15/83 (18%)

Query: 256 GPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAP 311
           GP G  G KG P    PGM   GPPG  GP G +GP G         QG  GPVG PG  
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--------QGNPGPVGDPG-- 426

Query: 312 GRDGSKGERGAPGPRGSPGPPGS 334
              G  G  G PG  G+PGPPG+
Sbjct: 427 -ERGPPGRAGLPGSDGAPGPPGT 448



 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 45/125 (36%), Positives = 49/125 (39%), Gaps = 40/125 (32%)

Query: 247 GPPGLPGGQGPP----------GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
           GP GL G +G P          G PGP+G  G  G PG  G PGP G  G  GP P  + 
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-PGRAG 435

Query: 297 IKQGRRGPVGPPGA----PGRDGSKGE------------------------RGAPGPRGS 328
           +  G  G  GPPG     P R GS G                         RG PGP G 
Sbjct: 436 L-PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 494

Query: 329 PGPPG 333
            G PG
Sbjct: 495 TGRPG 499


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%)

Query: 247  GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
            GPPG+ G  G       PGSPGP G+PG PGM G PG PGP G++GP GP       K G
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            + G  G PG  G  G+KG +G PGP GS G PG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%)

Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296
           PG PG PG  GP      PG  G KG  GFPG+PG    PG PG  G  G  G       
Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356
           I+   +G  G PGAPG  G  G  G PGP G PGPPG F F   M    R     + E+V
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222

Query: 357 FGHR 360
            GH+
Sbjct: 223 IGHK 226



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P  A D+G    G         LPGP G PG QG PG  G KG+PGF G  GPPG  GP+
Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G  G    L  I     G  GPPG PG  G +GE G PGP G+ GP G
Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300
           G PGLPG  GP G PGP G PG  G PGPPG  G  G+MGP GP   +         ++G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333
            +G  GPPG PG           R   KGE+G  G  G PGPPG
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG +G     G KG  G PG PG PG PGP G  GP G  P      QG +G  
Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333
           G PG PG  G +GE       PGP G PGPPG
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    D G  + GD         PGPPG  G  GP G+PG  GSPG PG PGP G  G +
Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G +GP         G RGP G PG PG  G  G RG  G  G PGP G
Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG QGPPG PG  G  G PG+PGP G+PG  G   P  P P       G +G +
Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720

Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337
           G PG  G  G  G+ G PG +G      PG PG+  F
Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
           P N   LG    G+  +      PG  G PG  G PG+PG +GSPG PG+ G  G PG +
Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329
           G  G  G P P ++SH+     + G +G  G P      G PG  G KG +G PGP G P
Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993

Query: 330 GPPG 333
           GP G
Sbjct: 994 GPRG 997



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290
            PG PGLPG +G  G  GP+G  G  G PGPPG PG           P GS G  G    P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 291  SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             P  SH+          G  GP GPPG  G  G  G  GAPG  G PGP G   F
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 43/89 (48%), Positives = 46/89 (51%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L G PG  G  G PGS G +G+ GFPG  G PG PG  G  G  G        + G  GP
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG PG  G KGE G PGP G  GP G
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300
           PGPPG PG +G   P G PGP+G  GFPG+PG  G  G RG  G  G   SP L     G
Sbjct: 54  PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP G  G PG  GSKGE+G PG  G+ G PG
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%)

Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285
           LPGP G PG  G G PG PGPKG  GFPG               +PG PG PG +G    
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746

Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               GP  P         G  G +G PG PG  G+ G  G  GPRG PG PG
Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%)

Query: 230  GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
            G ++ G K    +   PGP G PG  G  G PG  G+PG PG+PGP G PG +G  G  G
Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319

Query: 290  PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333
               +   +   G  GP+GP G PG  G  G        G+PGP G+PG PG
Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278
            P    DLG    G K L     + GPPGLPG  G PG  G +G  G  G+PGP G+    
Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 279  ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329
                  PGPRG+ G  G         +G RG  G PG PGR G+ G+ G  GP    G P
Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 330  GPPG 333
            GPPG
Sbjct: 1225 GPPG 1228



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%)

Query: 246  PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294
            PGPPGLPG    GQ G  G PG +GSPG PG PGPPG       G +GSMG  GP  P  
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 295  SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333
            +    G  G +G PG PG  G             KGE+G PG  GS GPPG
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%)

Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297
           PG PG PG        G GP G PG +G+ G PG PGPPG+ GPRG +    P P     
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                GP GPPG PG          PGP+G PG PGS
Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%)

Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295
           L+ +T +PGPPG P   GPPG PGP+G PG P   G  G PG PGP G  G  G      
Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               G  GP GP G  G  G+KG  G PG  G PG PG
Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298
           LPG PGLPG  G  G  GP+G PG PG PG  G PG     PRG+ G     P L+ +K 
Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827

Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333
            QGRRG  GP G PG     R G  GE G+PG             RG PG PG
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%)

Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285
           Y+PGPPGLPG                   +G PGSPG  G PGFPG PG  G PG +G  
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325
           G    P G    P       + GR+G  G PG PG              G KG++G PG 
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600

Query: 326 RGSPGPPG 333
            GSPG PG
Sbjct: 601 PGSPGSPG 608



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L  PPG  G  G  G+ G +G+PGFPG+PG  G  G  G  GP G         +G  GP
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226

Query: 305  VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334
             G PGA  PG+ G++   G RG+PG  G PGPPGS
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%)

Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281
           LPG PGLPG           G G PG PG +G+            PG PG PG  G  GP
Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790

Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           RG  G  GP  +        +G RG  G PG  G  G +G RG  GP+G PG PG
Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PG+PG QG  G  G +G PG PG+ GPPG+ G  G MG             G  GP G
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PPG PG  G +G  G PG +G  G PG+
Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           G+    +K    +  L G PG  G  G PGS G KG+ GFPG+ G  G  G +G +GP G
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              P   +     +G  G PG PG  G++G +G  GP G PG PGS
Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302
           PGP G  G QGP G PG  GSPG   PG+ G PG PG +GS G  G P  D         
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             +G PG+PG  GS G  G+PGP   PGPPG   F
Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PG PGL G +G            PGSPG  GSPG PG PGPPG PG    +   GP  D 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333
                G  G +G PG PG DG KGE G         PGP G PG PG
Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289
           LPG  GL G QG  G  GPKG PG        FPG  G PG PG +G MGP+G       
Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878

Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331
                 P  D      G  G +GPPG PG  G+            KG+RG PG +G  G 
Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938

Query: 332 PGS 334
            G+
Sbjct: 939 KGN 941



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG PG  G  G PGP G PG  G  GP G+PG  G  G  GP+ +     +G +G  
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414

Query: 306  GPPGAPGRDGSKGERGAPGPRGSP 329
            G PG  G DG  G +G  G  GSP
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%)

Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GP GLPG QGP   PG PG  GS         PGF G PG PG PG  G  G +G  P  
Sbjct: 67  GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125

Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329
           S  K      G  G +G PG PG  G KG++                    GAPGP+G P
Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185

Query: 330 GPPG 333
           GPPG
Sbjct: 186 GPPG 189



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%)

Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
           N  L GP G PG  GPPG          GP+G+ G PG+ G  GQ G RG  GP G    
Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333
               + G  G  G PG PG  G     G+RG PG  G  GPPG
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
            +PG  GL G  GP G PGP+G  G  G PG PG  G  GSMG MG P         G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 304  PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333
              G PG PG  G +G++G PG   G+ PGPPG
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 232  YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
            ++ GDK         G PG  G +G PG PG KG  G PG  GPPG  G  GS G  G  
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P L    +G  G +G  G PG  G +G  G PG  G PG PG
Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%)

Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284
           G    A +  LPG PG PG        +GPPG    PG  GSPG PG+ GP G+PG   +
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P  P P       G  G  G PG  G  G KG  G+PG  G PG PG
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276
            +P +  ++G  + G K        PG  G PG  G  G  G KG PG+     PG PGP 
Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070

Query: 277  GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328
            G PG  G MG  G    P P       G  GP GP GAPG  GS G  G PGP G     
Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 329  -----------------PGPPGS 334
                             PG PGS
Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302
            PGP G PG QG  G  G  G PG PG  G  G  GPRG  G  G P P      I  G+ 
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 303  GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333
            G  GPPG+ G  G+                 KG  G PGP+G PG  G
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277
           P+N  DL K   GDK        PGP GLPG      +G PG PG +G PG  G+PG PG
Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
             G +G+ G                     PG  G DG KG++G  GP G  GP   +D
Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%)

Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321
           G KG  G  G PGPPG PG +G  GP G          G +GP G PG PG  GSKG RG
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 322 A---PGPRGSPGPPGS 334
               PG  GSPG PG+
Sbjct: 95  ISGLPGFSGSPGLPGT 110



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274
           K I G +  A     PG PG  G  G PG PG +G PG                 PG PG
Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557

Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
             GQPG +G  G  G       P P       G +G  GPPG PG  GS      PGP G
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611

Query: 328 SPGPPG 333
             GPPG
Sbjct: 612 PAGPPG 617



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286
           GD  L      PG PG+ G +G PG         PGP G PG PG+ G  G PG +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333
             G SP  S    G  G  G PGA G  G KGE+G      G  G PG PG
Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%)

Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281
           LPGPPG PG  GPPG PG                        KG  G  G+ GPPG PG 
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243

Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306
                                   G  GP GPS  P  S+            QG+ G  G
Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303

Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337
            PG PG +G KG RG PG              G PG  G  ++
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 18/38 (47%), Positives = 21/38 (55%)

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           G +G  G  G PG  GS G++G  GP G PGP G   F
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%)

Query: 314 DGSKGERGA---PGPRGSPGPPG 333
           DG+KGE+G    PGP GSPG  G
Sbjct: 42  DGAKGEKGEKGFPGPPGSPGQKG 64


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%)

Query: 247  GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
            GPPG+ G  G       PGSPGP G+PG PGM G PG PGP G++GP GP       K G
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            + G  G PG  G  G+KG +G PGP GS G PG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%)

Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296
           PG PG PG  GP      PG  G KG  GFPG+PG    PG PG  G  G  G       
Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356
           I+   +G  G PGAPG  G  G  G PGP G PGPPG F F   M    R     + E+V
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222

Query: 357 FGHR 360
            GH+
Sbjct: 223 IGHK 226



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P  A D+G    G         LPGP G PG QG PG  G KG+PGF G  GPPG  GP+
Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G  G    L  I     G  GPPG PG  G +GE G PGP G+ GP G
Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300
           G PGLPG  GP G PGP G PG  G PGPPG  G  G+MGP GP   +         ++G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333
            +G  GPPG PG           R   KGE+G  G  G PGPPG
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG +G     G KG  G PG PG PG PGP G  GP G  P      QG +G  
Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333
           G PG PG  G +GE       PGP G PGPPG
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    D G  + GD         PGPPG  G  GP G+PG  GSPG PG PGP G  G +
Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G +GP         G RGP G PG PG  G  G RG  G  G PGP G
Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG QGPPG PG  G  G PG+PGP G+PG  G   P  P P       G +G +
Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720

Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337
           G PG  G  G  G+ G PG +G      PG PG+  F
Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
           P N   LG    G+  +      PG  G PG  G PG+PG +GSPG PG+ G  G PG +
Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329
           G  G  G P P ++SH+     + G +G  G P      G PG  G KG +G PGP G P
Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993

Query: 330 GPPG 333
           GP G
Sbjct: 994 GPRG 997



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290
            PG PGLPG +G  G  GP+G  G  G PGPPG PG           P GS G  G    P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 291  SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             P  SH+          G  GP GPPG  G  G  G  GAPG  G PGP G   F
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 43/89 (48%), Positives = 46/89 (51%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L G PG  G  G PGS G +G+ GFPG  G PG PG  G  G  G        + G  GP
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG PG  G KGE G PGP G  GP G
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300
           PGPPG PG +G   P G PGP+G  GFPG+PG  G  G RG  G  G   SP L     G
Sbjct: 54  PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP G  G PG  GSKGE+G PG  G+ G PG
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%)

Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285
           LPGP G PG  G G PG PGPKG  GFPG               +PG PG PG +G    
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746

Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               GP  P         G  G +G PG PG  G+ G  G  GPRG PG PG
Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%)

Query: 230  GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
            G ++ G K    +   PGP G PG  G  G PG  G+PG PG+PGP G PG +G  G  G
Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319

Query: 290  PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333
               +   +   G  GP+GP G PG  G  G        G+PGP G+PG PG
Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278
            P    DLG    G K L     + GPPGLPG  G PG  G +G  G  G+PGP G+    
Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 279  ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329
                  PGPRG+ G  G         +G RG  G PG PGR G+ G+ G  GP    G P
Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 330  GPPG 333
            GPPG
Sbjct: 1225 GPPG 1228



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%)

Query: 246  PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294
            PGPPGLPG    GQ G  G PG +GSPG PG PGPPG       G +GSMG  GP  P  
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 295  SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333
            +    G  G +G PG PG  G             KGE+G PG  GS GPPG
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%)

Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297
           PG PG PG        G GP G PG +G+ G PG PGPPG+ GPRG +    P P     
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                GP GPPG PG          PGP+G PG PGS
Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%)

Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295
           L+ +T +PGPPG P   GPPG PGP+G PG P   G  G PG PGP G  G  G      
Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               G  GP GP G  G  G+KG  G PG  G PG PG
Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298
           LPG PGLPG  G  G  GP+G PG PG PG  G PG     PRG+ G     P L+ +K 
Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827

Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333
            QGRRG  GP G PG     R G  GE G+PG             RG PG PG
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%)

Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285
           Y+PGPPGLPG                   +G PGSPG  G PGFPG PG  G PG +G  
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325
           G    P G    P       + GR+G  G PG PG              G KG++G PG 
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600

Query: 326 RGSPGPPG 333
            GSPG PG
Sbjct: 601 PGSPGSPG 608



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L  PPG  G  G  G+ G +G+PGFPG+PG  G  G  G  GP G         +G  GP
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226

Query: 305  VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334
             G PGA  PG+ G++   G RG+PG  G PGPPGS
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%)

Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281
           LPG PGLPG           G G PG PG +G+            PG PG PG  G  GP
Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790

Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           RG  G  GP  +        +G RG  G PG  G  G +G RG  GP+G PG PG
Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PG+PG QG  G  G +G PG PG+ GPPG+ G  G MG             G  GP G
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PPG PG  G +G  G PG +G  G PG+
Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           G+    +K    +  L G PG  G  G PGS G KG+ GFPG+ G  G  G +G +GP G
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              P   +     +G  G PG PG  G++G +G  GP G PG PGS
Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302
           PGP G  G QGP G PG  GSPG   PG+ G PG PG +GS G  G P  D         
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             +G PG+PG  GS G  G+PGP   PGPPG   F
Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PG PGL G +G            PGSPG  GSPG PG PGPPG PG    +   GP  D 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333
                G  G +G PG PG DG KGE G         PGP G PG PG
Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289
           LPG  GL G QG  G  GPKG PG        FPG  G PG PG +G MGP+G       
Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878

Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331
                 P  D      G  G +GPPG PG  G+            KG+RG PG +G  G 
Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938

Query: 332 PGS 334
            G+
Sbjct: 939 KGN 941



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG PG  G  G PGP G PG  G  GP G+PG  G  G  GP+ +     +G +G  
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414

Query: 306  GPPGAPGRDGSKGERGAPGPRGSP 329
            G PG  G DG  G +G  G  GSP
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%)

Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GP GLPG QGP   PG PG  GS         PGF G PG PG PG  G  G +G  P  
Sbjct: 67  GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125

Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329
           S  K      G  G +G PG PG  G KG++                    GAPGP+G P
Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185

Query: 330 GPPG 333
           GPPG
Sbjct: 186 GPPG 189



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%)

Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
           N  L GP G PG  GPPG          GP+G+ G PG+ G  GQ G RG  GP G    
Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333
               + G  G  G PG PG  G     G+RG PG  G  GPPG
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
            +PG  GL G  GP G PGP+G  G  G PG PG  G  GSMG MG P         G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 304  PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333
              G PG PG  G +G++G PG   G+ PGPPG
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 232  YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
            ++ GDK         G PG  G +G PG PG KG  G PG  GPPG  G  GS G  G  
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P L    +G  G +G  G PG  G +G  G PG  G PG PG
Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%)

Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284
           G    A +  LPG PG PG        +GPPG    PG  GSPG PG+ GP G+PG   +
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P  P P       G  G  G PG  G  G KG  G+PG  G PG PG
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276
            +P +  ++G  + G K        PG  G PG  G  G  G KG PG+     PG PGP 
Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070

Query: 277  GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328
            G PG  G MG  G    P P       G  GP GP GAPG  GS G  G PGP G     
Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 329  -----------------PGPPGS 334
                             PG PGS
Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302
            PGP G PG QG  G  G  G PG PG  G  G  GPRG  G  G P P      I  G+ 
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 303  GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333
            G  GPPG+ G  G+                 KG  G PGP+G PG  G
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277
           P+N  DL K   GDK        PGP GLPG      +G PG PG +G PG  G+PG PG
Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
             G +G+ G                     PG  G DG KG++G  GP G  GP   +D
Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%)

Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321
           G KG  G  G PGPPG PG +G  GP G          G +GP G PG PG  GSKG RG
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 322 A---PGPRGSPGPPGS 334
               PG  GSPG PG+
Sbjct: 95  ISGLPGFSGSPGLPGT 110



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274
           K I G +  A     PG PG  G  G PG PG +G PG                 PG PG
Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557

Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
             GQPG +G  G  G       P P       G +G  GPPG PG  GS      PGP G
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611

Query: 328 SPGPPG 333
             GPPG
Sbjct: 612 PAGPPG 617



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286
           GD  L      PG PG+ G +G PG         PGP G PG PG+ G  G PG +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333
             G SP  S    G  G  G PGA G  G KGE+G      G  G PG PG
Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%)

Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281
           LPGPPG PG  GPPG PG                        KG  G  G+ GPPG PG 
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243

Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306
                                   G  GP GPS  P  S+            QG+ G  G
Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303

Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337
            PG PG +G KG RG PG              G PG  G  ++
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 18/38 (47%), Positives = 21/38 (55%)

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           G +G  G  G PG  GS G++G  GP G PGP G   F
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%)

Query: 314 DGSKGERGA---PGPRGSPGPPG 333
           DG+KGE+G    PGP GSPG  G
Sbjct: 42  DGAKGEKGEKGFPGPPGSPGQKG 64


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score = 97.1 bits (240), Expect = 3e-20
 Identities = 48/93 (51%), Positives = 55/93 (59%), Gaps = 11/93 (11%)

Query: 247  GPPGLPGGQGP------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
            GPPG+ G  G       PGSPGP G+PG PGM G PG PGP G++GP GP       K G
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG-----KPG 1394

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            + G  G PG  G  G+KG +G PGP GS G PG
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 54/124 (43%), Positives = 60/124 (48%), Gaps = 11/124 (8%)

Query: 246 PGPPGLPGGQGP------PGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPMGPSPDLSH 296
           PG PG PG  GP      PG  G KG  GFPG+PG    PG PG  G  G  G       
Sbjct: 105 PGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEED 164

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLLMLADIRNDITELQEKV 356
           I+   +G  G PGAPG  G  G  G PGP G PGPPG F F   M    R     + E+V
Sbjct: 165 IELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM--GPRGPKGHMGERV 222

Query: 357 FGHR 360
            GH+
Sbjct: 223 IGHK 226



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 52/111 (46%), Positives = 57/111 (51%), Gaps = 4/111 (3%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P  A D+G    G         LPGP G PG QG PG  G KG+PGF G  GPPG  GP+
Sbjct: 1282 PGTAGDMGP--PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G  G    L  I     G  GPPG PG  G +GE G PGP G+ GP G
Sbjct: 1340 GPPGVRGDPGTLKII--SLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 48/104 (46%), Positives = 54/104 (51%), Gaps = 17/104 (16%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI------KQG 300
           G PGLPG  GP G PGP G PG  G PGPPG  G  G+MGP GP   +         ++G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 301 RRGPVGPPGAPG-----------RDGSKGERGAPGPRGSPGPPG 333
            +G  GPPG PG           R   KGE+G  G  G PGPPG
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 45/92 (48%), Positives = 48/92 (52%), Gaps = 4/92 (4%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  GLPG +G     G KG  G PG PG PG PGP G  GP G  P      QG +G  
Sbjct: 574 PGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVP 633

Query: 306 GPPGAPGRDGSKGERG----APGPRGSPGPPG 333
           G PG PG  G +GE       PGP G PGPPG
Sbjct: 634 GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPG 665



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 50/111 (45%), Positives = 54/111 (48%), Gaps = 10/111 (9%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
            P    D G  + GD         PGPPG  G  GP G+PG  GSPG PG PGP G  G +
Sbjct: 1067 PGPTGDPG--LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 283  GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G +GP         G RGP G PG PG  G  G RG  G  G PGP G
Sbjct: 1125 GIKGLLGP--------PGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 45/97 (46%), Positives = 52/97 (53%), Gaps = 5/97 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG QGPPG PG  G  G PG+PGP G+PG  G   P  P P       G +G +
Sbjct: 661 PGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSL 720

Query: 306 GPPGAPGRDGSKGERGAPGPRGS-----PGPPGSFDF 337
           G PG  G  G  G+ G PG +G      PG PG+  F
Sbjct: 721 GCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGF 757



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 15/124 (12%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
           P N   LG    G+  +      PG  G PG  G PG+PG +GSPG PG+ G  G PG +
Sbjct: 876 PGNPGILGP--PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAK 933

Query: 283 GSMGPMG-PSP-DLSHI-----KQGRRGPVGPP------GAPGRDGSKGERGAPGPRGSP 329
           G  G  G P P ++SH+     + G +G  G P      G PG  G KG +G PGP G P
Sbjct: 934 GEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPP 993

Query: 330 GPPG 333
           GP G
Sbjct: 994 GPRG 997



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 50/115 (43%), Positives = 53/115 (46%), Gaps = 23/115 (20%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----------PRGSMGPMG----P 290
            PG PGLPG +G  G  GP+G  G  G PGPPG PG           P GS G  G    P
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 291  SPDLSHI--------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             P  SH+          G  GP GPPG  G  G  G  GAPG  G PGP G   F
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 43/89 (48%), Positives = 46/89 (51%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L G PG  G  G PGS G +G+ GFPG  G PG PG  G  G  G        + G  GP
Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP 1069

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G PG PG  G KGE G PGP G  GP G
Sbjct: 1070 TGDPGLPGDMGKKGEMGQPGPPGHLGPAG 1098



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 48/93 (51%), Positives = 53/93 (56%), Gaps = 6/93 (6%)

Query: 246 PGPPGLPGGQG---PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--PSPDLSHIKQG 300
           PGPPG PG +G   P G PGP+G  GFPG+PG  G  G RG  G  G   SP L     G
Sbjct: 54  PGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG-TPG 112

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP G  G PG  GSKGE+G PG  G+ G PG
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPG 145



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 48/112 (42%), Positives = 52/112 (46%), Gaps = 23/112 (20%)

Query: 245 LPGPPGLPG--GQGPPGSPGPKGSPGFPG---------------MPGPPGQPGPRGSM-- 285
           LPGP G PG  G G PG PGPKG  GFPG               +PG PG PG +G    
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAV 746

Query: 286 ----GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               GP  P         G  G +G PG PG  G+ G  G  GPRG PG PG
Sbjct: 747 AMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798



 Score = 83.2 bits (204), Expect = 4e-16
 Identities = 46/111 (41%), Positives = 57/111 (51%), Gaps = 7/111 (6%)

Query: 230  GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
            G ++ G K    +   PGP G PG  G  G PG  G+PG PG+PGP G PG +G  G  G
Sbjct: 1260 GSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKG 1319

Query: 290  PSPDLSHIKQ-GRRGPVGPPGAPGRDGSKGE------RGAPGPRGSPGPPG 333
               +   +   G  GP+GP G PG  G  G        G+PGP G+PG PG
Sbjct: 1320 EKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 52/124 (41%), Positives = 60/124 (48%), Gaps = 23/124 (18%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---- 278
            P    DLG    G K L     + GPPGLPG  G PG  G +G  G  G+PGP G+    
Sbjct: 1115 PGPHGDLG--FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGET 1172

Query: 279  ------PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGP---RGSP 329
                  PGPRG+ G  G         +G RG  G PG PGR G+ G+ G  GP    G P
Sbjct: 1173 GLLRAPPGPRGNPGAQG--------AKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 330  GPPG 333
            GPPG
Sbjct: 1225 GPPG 1228



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 53/111 (47%), Positives = 58/111 (52%), Gaps = 23/111 (20%)

Query: 246  PGPPGLPG----GQ-GPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPS-PDL 294
            PGPPGLPG    GQ G  G PG +GSPG PG PGPPG       G +GSMG  GP  P  
Sbjct: 1224 PGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPG 1283

Query: 295  SHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGPPG 333
            +    G  G +G PG PG  G             KGE+G PG  GS GPPG
Sbjct: 1284 TAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPG 1334



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 44/97 (45%), Positives = 49/97 (50%), Gaps = 27/97 (27%)

Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297
           PG PG PG        G GP G PG +G+ G PG PGPPG+ GPRG +    P P     
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP----- 655

Query: 298 KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                GP GPPG PG          PGP+G PG PGS
Sbjct: 656 -----GPPGPPGPPGH---------PGPQGPPGIPGS 678



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 47/98 (47%), Positives = 52/98 (53%), Gaps = 15/98 (15%)

Query: 239 LASNTYLPGPPGLPGGQGPPGSPGPKGSPGFP---GMPGPPGQPGPRGSMGPMGPSPDLS 295
           L+ +T +PGPPG P   GPPG PGP+G PG P   G  G PG PGP G  G  G      
Sbjct: 648 LSVSTPVPGPPGPP---GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG------ 698

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               G  GP GP G  G  G+KG  G PG  G PG PG
Sbjct: 699 ---IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 52/113 (46%), Positives = 57/113 (50%), Gaps = 28/113 (24%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPG-----PRGSMGPMGPSPDLSHIK- 298
           LPG PGLPG  G  G  GP+G PG PG PG  G PG     PRG+ G     P L+ +K 
Sbjct: 772 LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQG----LPGLNGLKG 827

Query: 299 -QGRRGPVGPPGAPG-----RDGSKGERGAPG------------PRGSPGPPG 333
            QGRRG  GP G PG     R G  GE G+PG             RG PG PG
Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPG 880



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 51/128 (39%), Positives = 58/128 (45%), Gaps = 38/128 (29%)

Query: 244 YLPGPPGLPGG------------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM 285
           Y+PGPPGLPG                   +G PGSPG  G PGFPG PG  G PG +G  
Sbjct: 481 YIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 286 G----PMG----PSPDLSHIKQGRRGPVGPPGAPG------------RDGSKGERGAPGP 325
           G    P G    P       + GR+G  G PG PG              G KG++G PG 
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGD 600

Query: 326 RGSPGPPG 333
            GSPG PG
Sbjct: 601 PGSPGSPG 608



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 44/95 (46%), Positives = 53/95 (55%), Gaps = 13/95 (13%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L  PPG  G  G  G+ G +G+PGFPG+PG  G  G  G  GP G         +G  GP
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTG--------IEGFPGP 1226

Query: 305  VGPPGA--PGRDGSK---GERGAPGPRGSPGPPGS 334
             G PGA  PG+ G++   G RG+PG  G PGPPGS
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/115 (40%), Positives = 53/115 (46%), Gaps = 26/115 (22%)

Query: 245 LPGPPGLPG-----------GQGPPGSPGPKGS------------PGFPGMPGPPGQPGP 281
           LPG PGLPG           G G PG PG +G+            PG PG PG  G  GP
Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP 790

Query: 282 RGSMGPMGPSPDL---SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           RG  G  GP  +        +G RG  G PG  G  G +G RG  GP+G PG PG
Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 40/88 (45%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PG+PG QG  G  G +G PG PG+ GPPG+ G  G MG             G  GP G
Sbjct: 856 GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG-----------FPGAIGPPG 904

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           PPG PG  G +G  G PG +G  G PG+
Sbjct: 905 PPGNPGTPGQRGSPGIPGVKGQRGTPGA 932



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 43/106 (40%), Positives = 55/106 (51%), Gaps = 1/106 (0%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
           G+    +K    +  L G PG  G  G PGS G KG+ GFPG+ G  G  G +G +GP G
Sbjct: 280 GESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPG 339

Query: 290 -PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              P   +     +G  G PG PG  G++G +G  GP G PG PGS
Sbjct: 340 FRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 46/95 (48%), Positives = 51/95 (53%), Gaps = 16/95 (16%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRR 302
           PGP G  G QGP G PG  GSPG   PG+ G PG PG +GS G  G P  D         
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDA-------- 413

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             +G PG+PG  GS G  G+PGP   PGPPG   F
Sbjct: 414 --MGTPGSPGCAGSPGLPGSPGP---PGPPGDIVF 443



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 26/107 (24%)

Query: 246 PGPPGLPGGQGP-----------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           PG PGL G +G            PGSPG  GSPG PG PGPPG PG    +   GP  D 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPG--DIVFRKGPPGD- 450

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERG--------APGPRGSPGPPG 333
                G  G +G PG PG DG KGE G         PGP G PG PG
Sbjct: 451 ----HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG 493



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 48/123 (39%), Positives = 55/123 (44%), Gaps = 33/123 (26%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPG--------FPGMPGPPGQPGPRGSMGPMG------- 289
           LPG  GL G QG  G  GPKG PG        FPG  G PG PG +G MGP+G       
Sbjct: 819 LPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGN 878

Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGS------------KGERGAPGPRGSPGP 331
                 P  D      G  G +GPPG PG  G+            KG+RG PG +G  G 
Sbjct: 879 PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938

Query: 332 PGS 334
            G+
Sbjct: 939 KGN 941



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 39/84 (46%), Positives = 45/84 (53%), Gaps = 5/84 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG PG  G  G PGP G PG  G  GP G+PG  G  G  GP+ +     +G +G  
Sbjct: 1360 PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSK 1414

Query: 306  GPPGAPGRDGSKGERGAPGPRGSP 329
            G PG  G DG  G +G  G  GSP
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSP 1438



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 52/124 (41%), Positives = 57/124 (45%), Gaps = 38/124 (30%)

Query: 247 GPPGLPGGQGP---PGSPGPKGS---------PGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           GP GLPG QGP   PG PG  GS         PGF G PG PG PG  G  G +G  P  
Sbjct: 67  GPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVG-VPGC 125

Query: 295 SHIK-----QGRRGPVGPPGAPGRDGSKGER--------------------GAPGPRGSP 329
           S  K      G  G +G PG PG  G KG++                    GAPGP+G P
Sbjct: 126 SGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLP 185

Query: 330 GPPG 333
           GPPG
Sbjct: 186 GPPG 189



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 11/103 (10%)

Query: 242 NTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
           N  L GP G PG  GPPG          GP+G+ G PG+ G  GQ G RG  GP G    
Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843

Query: 294 LSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGSPGPPG 333
               + G  G  G PG PG  G     G+RG PG  G  GPPG
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPG 886



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 44/92 (47%), Positives = 50/92 (54%), Gaps = 3/92 (3%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
            +PG  GL G  GP G PGP+G  G  G PG PG  G  GSMG MG P         G  G
Sbjct: 977  MPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPG 1036

Query: 304  PVGPPGAPGRDGSKGERGAPG-PRGS-PGPPG 333
              G PG PG  G +G++G PG   G+ PGPPG
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPG 1068



 Score = 74.3 bits (181), Expect = 2e-13
 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 5/102 (4%)

Query: 232  YITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
            ++ GDK         G PG  G +G PG PG KG  G PG  GPPG  G  GS G  G  
Sbjct: 949  HVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPG-E 1007

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P L    +G  G +G  G PG  G +G  G PG  G PG PG
Sbjct: 1008 PGL----RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPG 1045



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 46/109 (42%), Positives = 52/109 (47%), Gaps = 10/109 (9%)

Query: 235 GDKVLASNTYLPGPPGLPG-------GQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGS 284
           G    A +  LPG PG PG        +GPPG    PG  GSPG PG+ GP G+PG   +
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P  P P       G  G  G PG  G  G KG  G+PG  G PG PG
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG 526



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 52/143 (36%), Positives = 58/143 (40%), Gaps = 38/143 (26%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF-----PGMPGPP 276
            +P +  ++G  + G K        PG  G PG  G  G  G KG PG+     PG PGP 
Sbjct: 1013 IPGSMGNMG--MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPT 1070

Query: 277  GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS---- 328
            G PG  G MG  G    P P       G  GP GP GAPG  GS G  G PGP G     
Sbjct: 1071 GDPGLPGDMGKKGEMGQPGPP------GHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFK 1124

Query: 329  -----------------PGPPGS 334
                             PG PGS
Sbjct: 1125 GIKGLLGPPGIRGPPGLPGFPGS 1147



 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 44/108 (40%), Positives = 48/108 (44%), Gaps = 20/108 (18%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD--LSHIKQGRR 302
            PGP G PG QG  G  G  G PG PG  G  G  GPRG  G  G P P      I  G+ 
Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238

Query: 303  GPVGPPGAPGRDGS-----------------KGERGAPGPRGSPGPPG 333
            G  GPPG+ G  G+                 KG  G PGP+G PG  G
Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 45/119 (37%), Positives = 54/119 (45%), Gaps = 26/119 (21%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGG-----QGPPGSPGPKGSPGFPGMPGPPG 277
           P+N  DL K   GDK        PGP GLPG      +G PG PG +G PG  G+PG PG
Sbjct: 251 PDNRTDL-KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPG 309

Query: 278 QPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
             G +G+ G                     PG  G DG KG++G  GP G  GP   +D
Sbjct: 310 SEGVKGNRGF--------------------PGLMGEDGIKGQKGDIGPPGFRGPTEYYD 348



 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 38/76 (50%), Positives = 41/76 (53%), Gaps = 11/76 (14%)

Query: 262 GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG 321
           G KG  G  G PGPPG PG +G  GP G          G +GP G PG PG  GSKG RG
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG--------LPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 322 A---PGPRGSPGPPGS 334
               PG  GSPG PG+
Sbjct: 95  ISGLPGFSGSPGLPGT 110



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 48/126 (38%), Positives = 52/126 (41%), Gaps = 29/126 (23%)

Query: 231 KYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------PGMPG 274
           K I G +  A     PG PG  G  G PG PG +G PG                 PG PG
Sbjct: 498 KGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557

Query: 275 PPGQPGPRGSMGPMG-------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
             GQPG +G  G  G       P P       G +G  GPPG PG  GS      PGP G
Sbjct: 558 LRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS------PGPAG 611

Query: 328 SPGPPG 333
             GPPG
Sbjct: 612 PAGPPG 617



 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 47/111 (42%), Positives = 53/111 (47%), Gaps = 14/111 (12%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS--------PGPKGSPGFPGMPGPPGQPGPRGSMG 286
           GD  L      PG PG+ G +G PG         PGP G PG PG+ G  G PG +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPG 333
             G SP  S    G  G  G PGA G  G KGE+G      G  G PG PG
Sbjct: 509 LKG-SPG-SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 51/163 (31%), Positives = 57/163 (34%), Gaps = 70/163 (42%)

Query: 245 LPGPPGLPGGQGPPGSPG-----------------------PKGSPGFPGMPGPPGQPGP 281
           LPGPPG PG  GPPG PG                        KG  G  G+ GPPG PG 
Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243

Query: 282 -----------------------RGSMGPMGPS--PDLSHIK----------QGRRGPVG 306
                                   G  GP GPS  P  S+            QG+ G  G
Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303

Query: 307 PPGAPGRDGSKGERGAPG------------PRGSPGPPGSFDF 337
            PG PG +G KG RG PG              G PG  G  ++
Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEY 346



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 18/38 (47%), Positives = 21/38 (55%)

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           G +G  G  G PG  GS G++G  GP G PGP G   F
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF 80



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 14/23 (60%), Positives = 16/23 (69%), Gaps = 3/23 (13%)

Query: 314 DGSKGERGA---PGPRGSPGPPG 333
           DG+KGE+G    PGP GSPG  G
Sbjct: 42  DGAKGEKGEKGFPGPPGSPGQKG 64


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 96.7 bits (239), Expect = 3e-20
 Identities = 49/102 (48%), Positives = 54/102 (52%), Gaps = 15/102 (14%)

Query: 247 GPPGLPGGQGPPGSPG---------PKGSPGFPGMPGP------PGQPGPRGSMGPMGPS 291
           GPPGLPG  GP G+ G         P+G+PG PG  GP      PG PG +G  G  GP 
Sbjct: 416 GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPP 475

Query: 292 PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  +G  GP GPPG PG  G  GE G PGP G PGPPG
Sbjct: 476 GPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 49/92 (53%), Positives = 55/92 (59%), Gaps = 4/92 (4%)

Query: 246 PGPPGLPGGQGP---PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP-DLSHIKQGR 301
           PG PGL G +GP   PG PG KG  G  G+PG PG  GP G+MGP GP     SH   G 
Sbjct: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           +G  GP G  G  G+KGERG+PG  G PG PG
Sbjct: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392



 Score = 93.2 bits (230), Expect = 4e-19
 Identities = 51/115 (44%), Positives = 58/115 (50%), Gaps = 27/115 (23%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------------P 292
           PG  G PG  G PG  GPKG+PG PG  G PG  GP G  GP+GP+             P
Sbjct: 382 PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP 441

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAP--------------GPRGSPGPPG 333
             +    G RGP+GPPG PG  GSKG+ G+P              GP G PGPPG
Sbjct: 442 RGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 496



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 51/117 (43%), Positives = 58/117 (49%), Gaps = 28/117 (23%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGF--------PGMPGPPGQ-----------PGPRGSMG 286
           PGPPG  G +G PG  GP G PG+        PG+PGPPG            PG  G  G
Sbjct: 62  PGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERG 121

Query: 287 PMGPSPDLSHI-KQGRRGPVGPPG--------APGRDGSKGERGAPGPRGSPGPPGS 334
           P GP  D+      G RGP GPPG         PG+ G +G  GAPGPRG PG  G+
Sbjct: 122 PYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 50/105 (47%), Positives = 56/105 (53%), Gaps = 16/105 (15%)

Query: 245 LPGP-----PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG---PMGPSPDLSH 296
           +PGP     PG PG QGP G+PGP+G PG  G PG PG  G +G MG   P  P      
Sbjct: 146 IPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP 205

Query: 297 IKQGRRGPVGPP--------GAPGRDGSKGERGAPGPRGSPGPPG 333
             QG  GP GPP        G PG+ G KG+RG PG  G  GPPG
Sbjct: 206 GPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 46/92 (50%), Positives = 50/92 (54%), Gaps = 5/92 (5%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           LPG PGL G  G  G  GPKG PG  G+PGP G+ GP G  G  G   +      G  G 
Sbjct: 330 LPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG--SPGSDGK 387

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSP---GPPG 333
            G PG PG DG KG  G PGP+G P   GPPG
Sbjct: 388 PGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG 419



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 49/105 (46%), Positives = 52/105 (49%), Gaps = 23/105 (21%)

Query: 246 PGPPGLPGGQGP-----------------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPM 288
           PG  GLPG QGP                 PG PG KG  GFPG  GP G PGP+G  G  
Sbjct: 199 PGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGER 258

Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP         G+ G  G PG PG  G+KG  GAPG  G PGPPG
Sbjct: 259 GPEGI------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG 297



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 49/100 (49%), Positives = 54/100 (54%), Gaps = 13/100 (13%)

Query: 247 GPPGLPGGQGPPGSPGPKG-----SPGFPGMPGPPGQ---PGPRGSMGPMGP----SPDL 294
           GP G PG QGPPG  GP+G     + G PG PG PG    PG  G  GP GP     P L
Sbjct: 244 GPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGL 303

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             +K G RGP G PG PG  G +G  G PG  G  GPPG+
Sbjct: 304 PGLK-GERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGN 342



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 49/102 (48%), Positives = 52/102 (50%), Gaps = 14/102 (13%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PGLPG  G  G  GPKG  G  G+PGP G PGP G  GP G S      +QG  G  
Sbjct: 108 PGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAP 167

Query: 306 GP---------PGAPGRDGSKGER-----GAPGPRGSPGPPG 333
           GP         PG PG +G KGE      G PG RG PGP G
Sbjct: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQG 209



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 45/89 (50%), Positives = 48/89 (53%), Gaps = 8/89 (8%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG PGL G +G PG PGPKG PG  G PG PG  GP G+ G  G +        G  GP 
Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN--------GEAGPR 442

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG  G  G  G PG  GS G PGS
Sbjct: 443 GAPGIPGTRGPIGPPGIPGFPGSKGDPGS 471



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 50/106 (47%), Positives = 56/106 (52%), Gaps = 8/106 (7%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G K +  +  LPGP G  G  GP G PG KG  G PG  G PG PG  G  GP G +P L
Sbjct: 347 GPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG-NPGL 405

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAP------GPRGSPGPPGS 334
              K G  G  GPPG PG  G  G +G P      GPRG+PG PG+
Sbjct: 406 PGPK-GDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT 450



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 46/95 (48%), Positives = 49/95 (51%), Gaps = 14/95 (14%)

Query: 253 GGQGPPGSPGPKGSPGFPGMPGPPGQP--------GPRGSMGPMGPS----PDLSHI--K 298
           G QG PG PGP G  G PG  GPPG+P        G  G  GP GPS    P +  +  K
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116

Query: 299 QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G RGP GP G  G  G  G RG PGP G PGP G
Sbjct: 117 PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG 151



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 47/105 (44%), Positives = 55/105 (52%), Gaps = 17/105 (16%)

Query: 246 PGPPGLPGGQGPPGSPG---PKGSPGF--PGMPGP---------PGQPGPRGSMGPMG-- 289
           PG PG+PG +G PG+PG   P G PGF  PG+PG          PG PG +G  GP G  
Sbjct: 272 PGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             P L+    G  GP GP G PG  G  G +G  GP G  G PG+
Sbjct: 332 GKPGLTG-PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGA 375



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 44/99 (44%), Positives = 48/99 (48%), Gaps = 17/99 (17%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKG--------SPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           T  PGP G PG +G PG PG  G        +PG PG  G PG  GP G  GP G     
Sbjct: 164 TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG----- 218

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                G+RG  G PG PG  G +G  G  GP G PGP G
Sbjct: 219 ----VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG 253



 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 32/79 (40%), Positives = 35/79 (44%), Gaps = 16/79 (20%)

Query: 246 PGPPG--------LPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGPS 291
           PGPPG        L G  GPPG PGP+G       PG PG PGPPGQ          G  
Sbjct: 472 PGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531

Query: 292 PDLS--HIKQGRRGPVGPP 308
           P LS   +    +G  G P
Sbjct: 532 PSLSGTPLVSANQGVTGMP 550


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score = 96.3 bits (238), Expect = 4e-20
 Identities = 46/92 (50%), Positives = 56/92 (60%), Gaps = 5/92 (5%)

Query: 245 LPGPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           L G PGLPG +G  G+PG   P+G  G  G  GPPG PGP G+ GP G +       +G 
Sbjct: 152 LDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTG--KDGPRGA 209

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           +GP GP G PG+DG  G +G PGP+G PG PG
Sbjct: 210 QGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPG 241



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 43/89 (48%), Positives = 46/89 (51%), Gaps = 11/89 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG +GPPG  G  G  G  G  GP G+PG  G MGP GP            GP 
Sbjct: 186 PGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPP-----------GPK 234

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G PG PG+ G  G    PGP G  G PGS
Sbjct: 235 GEPGVPGKKGDDGTPSQPGPPGPKGEPGS 263



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 50/120 (41%), Positives = 59/120 (49%), Gaps = 7/120 (5%)

Query: 221 LLPNNAADLGKYITGDKVLASNTYLPGPPGL---PGGQGPPGSPGPKGSPGFP---GMPG 274
           LL      L K  T  +  +     PGPPG    PG +G PG PG  G  G+P   G+ G
Sbjct: 95  LLREKLDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDG 154

Query: 275 PPGQPGPRGSMGPMGP-SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            PG PGP+G  G  G   P     + G  GP GPPG PG  G  G+ G  GPRG+ GP G
Sbjct: 155 KPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAG 214



 Score = 86.7 bits (213), Expect = 4e-17
 Identities = 44/91 (48%), Positives = 49/91 (53%), Gaps = 5/91 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GP G PG +G PG PG KG  G P  PGPPG  G  GSMGP G +        G  GP G
Sbjct: 226 GPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG-----VDGAPGPKG 280

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            PG  G DG+ G RGAPG +G  G     D+
Sbjct: 281 EPGHRGTDGAAGPRGAPGLKGEQGDTVVIDY 311



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 48/105 (45%), Positives = 54/105 (51%), Gaps = 18/105 (17%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GPPG  G  GPPG PG KG  G PG PG  G+ GP+G  G  G  P  + +K G  G 
Sbjct: 319 LKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPG-EPGPAGLK-GEAGE 376

Query: 305 VGPPGAPGRDGSKGERG----------------APGPRGSPGPPG 333
           +G  G PG DG KGE+G                 PGP G PGPPG
Sbjct: 377 MGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPG 421



 Score = 84.0 bits (206), Expect = 2e-16
 Identities = 48/115 (41%), Positives = 56/115 (48%), Gaps = 27/115 (23%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS-------- 295
           P  PG PG +G PGS GP+G  G  G PGP G+PG RG+ G  GP  +P L         
Sbjct: 249 PSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVV 308

Query: 296 --------HIKQGRRGPVGPPGAPGRDGSKGERGAP---------GPRGSPGPPG 333
                      +G  GP GPPG PG  G+KGE G P         GP+G  G PG
Sbjct: 309 IDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPG 363



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 48/109 (44%), Positives = 53/109 (48%), Gaps = 23/109 (21%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PGPPG PG  G  G  GPKG  G  G  G  G+ GP G  GP+GP P L  +  G +G  
Sbjct: 414 PGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGP-PGLIGL-PGTKGEK 471

Query: 306 GPPGAPGRD---------------GSKGERGAP------GPRGSPGPPG 333
           G PG PG D               G KGERG P      G +G PGPPG
Sbjct: 472 GRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPG 520



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 41/81 (50%), Positives = 47/81 (58%), Gaps = 8/81 (9%)

Query: 257 PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGS 316
           PPG PG +G PG  G PGPPGQ G  G  GP+G        K G  GP G  GAPG  G 
Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDG-----KPGLPGPKGEKGAPGDFGP 173

Query: 317 KGERG---APGPRGSPGPPGS 334
           +G++G   A GP G PGPPG+
Sbjct: 174 RGDQGQDGAAGPPGPPGPPGA 194



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 51/126 (40%), Positives = 58/126 (46%), Gaps = 38/126 (30%)

Query: 246 PGPPGLPGGQGP---PGSPG------PKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLS 295
           PGPPG+PG +G    PG+PG      PKG  G PG PGP G  G  G MG  G P  D  
Sbjct: 329 PGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGL 388

Query: 296 HIKQGRR----------------GPVGPPGAP------------GRDGSKGERGAPGPRG 327
             ++G                  GP GPPG P            G DG+KGE+GA G RG
Sbjct: 389 KGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERG 448

Query: 328 SPGPPG 333
             G PG
Sbjct: 449 PSGLPG 454



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 42/88 (47%), Positives = 45/88 (51%), Gaps = 14/88 (15%)

Query: 247 GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           GP GLPG  GPPG    PG KG  G PG PG  G PGPRG  G            +  RG
Sbjct: 448 GPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKG-----------DRSERG 496

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGP 331
             G  G PGR G KG++G PGP G   P
Sbjct: 497 EKGERGVPGRKGVKGQKGEPGPPGLDQP 524



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 50/137 (36%), Positives = 54/137 (39%), Gaps = 37/137 (27%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF----------------------- 269
           I G+K        PG PG  G +G  G  G  G PG                        
Sbjct: 349 IDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLI 408

Query: 270 --PGMPGPPGQPGPRGSMGPMGPSPDLSHIK-----------QGRRGPVGPPGAPGRDGS 316
             PG PGPPG PGP G  G  GP   L   K            G  GPVGPPG  G  G+
Sbjct: 409 VEPGPPGPPGPPGPMGLQGIQGPK-GLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGT 467

Query: 317 KGERGAPGPRGSPGPPG 333
           KGE+G PG  G  G PG
Sbjct: 468 KGEKGRPGEPGLDGFPG 484



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 30/67 (44%), Positives = 32/67 (47%), Gaps = 20/67 (29%)

Query: 275 PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKG------ERGAPGPRGS 328
           PPG PG RG              K GRRG  GPPG  GRDG  G      + G PGP+G 
Sbjct: 119 PPGPPGRRG--------------KPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGE 164

Query: 329 PGPPGSF 335
            G PG F
Sbjct: 165 KGAPGDF 171



 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 20/48 (41%), Positives = 24/48 (50%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
           PGP G  G +   G  G +G PG  G+ G  G+PGP G   P    PD
Sbjct: 483 PGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPD 530



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 28/72 (38%), Positives = 28/72 (38%), Gaps = 18/72 (25%)

Query: 246 PGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           PG PGL G  GP G  G       KG  G PG  G  GQ G  G  G   P         
Sbjct: 474 PGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPC-------- 525

Query: 300 GRRGPVGPPGAP 311
               PVGP G P
Sbjct: 526 ----PVGPDGLP 533



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 2/49 (4%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF--PGMPGPPGQPGP 281
           G+K   S     G  G+PG +G  G  G  G PG   P   GP G P P
Sbjct: 487 GEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVP 535


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 48/90 (53%), Positives = 53/90 (58%), Gaps = 5/90 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPG---FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
            G  G PG +GPPG  GPKGSPG   FPG PGPPG+PGP G  GP G   D    + G+ G
Sbjct: 1318 GAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDG--EPGQTG 1375

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP G PG  G  G+RG PGP G  G  G
Sbjct: 1376 SPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405



 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 47/89 (52%), Positives = 50/89 (56%), Gaps = 1/89 (1%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
            PGP G PG  GPPG PGP G  G PG  G  G+PG  GS GP G P P     K+G  GP
Sbjct: 1338 PGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             GP G  G  G+KGE G  GP G  GP G
Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIG 1426



 Score = 94.7 bits (234), Expect = 1e-19
 Identities = 52/113 (46%), Positives = 60/113 (53%), Gaps = 15/113 (13%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------PGQPGPRGSMGPM 288
            G+K       L GPPG  G  GP G+PG  G  G  G+PGP      PG PGP G  GPM
Sbjct: 1405 GEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPM 1464

Query: 289  GPSPDLSHIK--------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP P L  +K        +G  G +G  G PG  G KG+RG PGP+GS GP G
Sbjct: 1465 GP-PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKG 1516



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 51/112 (45%), Positives = 57/112 (50%), Gaps = 25/112 (22%)

Query: 247 GPPG------LPGGQGPPGSPGPKGSPGFPGMPGP---------PGQPGPRGSMGPMGPS 291
           GPPG      +PG  G PG  GPKGS GFPG PG          PG+PGPRG  GP GP 
Sbjct: 859 GPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR 918

Query: 292 PDLS----------HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +                G  GP GPPG  G +G +G  G PGP+G PGPPG
Sbjct: 919 GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPG 970



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 47/100 (47%), Positives = 54/100 (54%), Gaps = 11/100 (11%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+      T  PGPPG+ G QGP G  GP G  G PG PGPPG+ G  G  G        
Sbjct: 982  GETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAG-------- 1033

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
               K+G +G  GP G PG+DG  G RG PG RG PGP G+
Sbjct: 1034 ---KEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 52/108 (48%), Positives = 57/108 (52%), Gaps = 19/108 (17%)

Query: 246  PGPPGLPG--GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-SPDLSHIKQGR 301
            PGPPG PG  GQ GPPG  G  G PG  G PGP G+PGP G  G  GP  P     +QG 
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406

Query: 302  RG---------------PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            +G               P+GP GAPG+ G  G RG PGP G  G PGS
Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454



 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 53/111 (47%), Positives = 56/111 (50%), Gaps = 22/111 (19%)

Query: 245  LPGPPG---LPGGQGPPGSPGPKGSPG------------FPGMPGPPGQPGPR------G 283
            LPGP G   L G +GPPG PGP GSPG             PG PGP G PGP       G
Sbjct: 1064 LPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPG 1123

Query: 284  SMGPMGPS-PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP GP+  D      G  GP GP G PG DG KGE G PG +GS G  G
Sbjct: 1124 EKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKG 1174



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/98 (45%), Positives = 51/98 (52%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----------PSPDLS 295
           PGP GL G +GPPG PGP G  G  G PGP G  GP+G  GP G          P P  +
Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               G +GP+G PG PG  G+ G  G PG  G PG  G
Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKG 775



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 44/88 (50%), Positives = 51/88 (57%), Gaps = 1/88 (1%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGPV 305
            GPPG  G +G  G  GP G+ G PG  GPPG  GP+GS GP+G P       + G  G  
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G DG  G+ G+PGP G PGP G
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSG 1387



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 49/105 (46%), Positives = 54/105 (51%), Gaps = 17/105 (16%)

Query: 235 GDKVLASNTYLPGPPGL---PGGQGPPGSPGPKGSPGFPGMPGP---PGQPGPRGSMGPM 288
           GD+       LPG  G    PG  GPPG PG  G  G  G  GP   PG+PGPRG +GP 
Sbjct: 628 GDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK 687

Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP            GP GPPG  G DG  G +G  GP+G PGPPG
Sbjct: 688 GPP-----------GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPG 721



 Score = 90.5 bits (223), Expect = 2e-18
 Identities = 54/113 (47%), Positives = 57/113 (50%), Gaps = 25/113 (22%)

Query: 246  PGPPGLPGGQGPPGS---------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            PGP GLPG  GPPG          PGP G+ G  G  GPPG PGP GS G  GP+     
Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100

Query: 297  IK-QGRRGPVGPP------GAP---------GRDGSKGERGAPGPRGSPGPPG 333
            I   GR GP GPP      GAP         GRDG +G  G PGP G  GPPG
Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPG 1153



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 46/88 (52%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  G  G QGP G PGPKG PG PG  G PG PG RG  G            QG+ GP 
Sbjct: 945  PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG-----------FQGKTGPP 993

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G  GE G  G RG PGPPG
Sbjct: 994  GPPGVVGPQGPTGETGPMGERGHPGPPG 1021



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 45/88 (51%), Positives = 47/88 (53%), Gaps = 11/88 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PGPPG  G QG PG PG KG  G  G  GPPG PGPRG  G  G             GP 
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGAD-----------GPQ 1269

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPPG  G  G+ GE+G PG  G PG PG
Sbjct: 1270 GPPGGIGNPGAVGEKGEPGEAGEPGLPG 1297



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 50/111 (45%), Positives = 55/111 (49%), Gaps = 29/111 (26%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSMGPMGPSPDLSHI 297
            GPPGLPG +G  G  G KG PG  G+ GPPG+         PGP+GS GP G        
Sbjct: 1465 GPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT--- 1521

Query: 298  KQGRRGPVGPPGAPGRDGS---------------KGERGAPGPRGSPGPPG 333
              G  GP+GPPG PG  G                KGE G PGP G PGPPG
Sbjct: 1522 --GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 47/93 (50%), Positives = 48/93 (51%), Gaps = 14/93 (15%)

Query: 247  GPPGLPGGQGPPGS------PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
            GP G PGG G PG+      PG  G PG PG  GPPG  G RG  G  GPS        G
Sbjct: 1267 GPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPS--------G 1318

Query: 301  RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              GP GP G PG DG KG  G  G  G PGPPG
Sbjct: 1319 AAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 46/98 (46%), Positives = 52/98 (53%), Gaps = 10/98 (10%)

Query: 246 PGPPGLPG---------GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLS 295
           PGP G PG          +G PG  GPKG  GF G+ G PG+ G RG  GP G P P   
Sbjct: 600 PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             ++G  G VGP G PG  G +G  G  GP G PGPPG
Sbjct: 660 DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 47/102 (46%), Positives = 56/102 (54%), Gaps = 13/102 (12%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ---------PGPRGSMGPMGPSPDLSH 296
           PGPPG PG  G  G PGPKG+ G  G PGPPGQ         PGP+G++GP G    L  
Sbjct: 690 PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGK 749

Query: 297 IK-QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
               G  G  GPPG PG++G  GE+G    +G PGP G   +
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGG---QGPPGPQGPIGY 788



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 45/94 (47%), Positives = 53/94 (56%), Gaps = 8/94 (8%)

Query: 243 TYLPGPPGLPGGQGPPGSPGP---KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ 299
           T + G PG  G  GP G PGP   +G+PG  G+PGP G  GP G  GP+G  P L     
Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLG-KPGL----P 753

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  G  GPPG PG++G  GE+G  GP G  GP G
Sbjct: 754 GMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIG 787



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 22/110 (20%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMG---------- 289
           PG PG+PG  GPPG PG +G PG  G  GPPG       PGPRG  G  G          
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809

Query: 290 ------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                 P        +G RG +GPPG  G DG +G +G  GP G PGP G
Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLG 859



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 44/90 (48%), Positives = 49/90 (54%), Gaps = 1/90 (1%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ-GRRG 303
            L GP GLPG  GP G PG  G  G  G PG  G  G +G  GP GP+     I Q G  G
Sbjct: 1136 LQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSG 1195

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G PG  G+ G  G++G  GPRG PGPPG
Sbjct: 1196 ADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 50/125 (40%), Positives = 57/125 (45%), Gaps = 38/125 (30%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM----------------GPM 288
           LPGPPG  G  G  G PG +G PG PG+PG  G PGP G+M                GPM
Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPM 538

Query: 289 --------------------GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328
                               GP+  +     GR GPVGPPG+ G  G  G+ G  GPRG 
Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMG--LTGRPGPVGPPGSGGLKGEPGDVGPQGPRGV 596

Query: 329 PGPPG 333
            GPPG
Sbjct: 597 QGPPG 601



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 47/95 (49%), Positives = 51/95 (53%), Gaps = 13/95 (13%)

Query: 246  PGPPGLPGGQGPPGSPGP------KGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIK 298
            PGP G PG +GPPG  GP      KG+ G  G+ GPPG+ GP G  G  G P PD     
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPD----- 1437

Query: 299  QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G RG  GP G  G  GS G  G PGP G PG PG
Sbjct: 1438 -GLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG 1471



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 45/95 (47%), Positives = 53/95 (55%), Gaps = 8/95 (8%)

Query: 245  LPGPPGLPG-----GQ-GPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIK 298
            LPGPPG  G     GQ GPPG PGP+G  G PG  GP G PG  G+ G +G   +    +
Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPG--E 1289

Query: 299  QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  G  G PG  G +GE+G  GP G+ GPPG
Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG 1324



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 47/100 (47%), Positives = 49/100 (49%), Gaps = 1/100 (1%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK         G  G  G QGPPG  GP+G  G PG  G  G+PGPRG  G  G   D 
Sbjct: 1156 GDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDE 1215

Query: 295  S-HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  GPVG  G PG  G KGE G  G  G PGPPG
Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 49/107 (45%), Positives = 52/107 (48%), Gaps = 23/107 (21%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GP G  G  G PG  GP GS G  G PG  G  GPRG  GP GP+      K GRRG 
Sbjct: 557 LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG-----KPGRRGR 611

Query: 305 VGPPGA---PGRDGSKGE---------------RGAPGPRGSPGPPG 333
            G  GA   PG+ G KG+               RG PGP G PGPPG
Sbjct: 612 AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 41/88 (46%), Positives = 50/88 (56%), Gaps = 2/88 (2%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG PG  G  G  G  G  G PG PGP G  GP+G  GP GP P ++ +  G+ GP G
Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGP-PGVTGM-DGQPGPKG 709

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             G  G  G  G++G PG +G PGP G+
Sbjct: 710 NVGPQGEPGPPGQQGNPGAQGLPGPQGA 737



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 44/103 (42%), Positives = 48/103 (46%), Gaps = 26/103 (25%)

Query: 246  PGPPGLPGGQG---------------PPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
            PGPPG PG QG               P G PG  G PG  G PG  G PGP G++G    
Sbjct: 1017 PGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALG---- 1072

Query: 291  SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                    +G  GP GPPG  G  G +G  GA GP G PG PG
Sbjct: 1073 -------LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPG 1108



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 43/95 (45%), Positives = 49/95 (51%), Gaps = 7/95 (7%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQGR 301
           PGP G  G QG PG PG +G+PG  G+PGP G  GP G  GP+G    P    +    G 
Sbjct: 705 PGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764

Query: 302 RGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
            G  GPPG  G  G  G +G    PGPRG  G  G
Sbjct: 765 PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADG 799



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 45/101 (44%), Positives = 51/101 (50%), Gaps = 13/101 (12%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGM------------PGPPGQPGPRGSMGPMG-PSPD 293
            GPPG  G QGP G PGP G+ G PG              GP G PGP G +G  G P P 
Sbjct: 1177 GPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPP 1236

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                + G  G +GPPG PG  G  G  GA GP+G PG  G+
Sbjct: 1237 GEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGN 1277



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 42/93 (45%), Positives = 49/93 (52%), Gaps = 14/93 (15%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPG------FPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQG 300
           GP G  G  GP G PGP G PG       PG+PG PG+ GP+GS+G  G          G
Sbjct: 841 GPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPG--------FPG 892

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  G PG+ G +G+RG  GPRG  GP G
Sbjct: 893 ANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 47/119 (39%), Positives = 50/119 (42%), Gaps = 28/119 (23%)

Query: 247 GPPGLPGGQGPPGSPGP------------------------KGSPGFPGMPGPPGQPGPR 282
           GPPG  GGQGPPG  GP                        KG  GFPG  G  G  G R
Sbjct: 769 GPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828

Query: 283 GSMGPMGP----SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
           G +GP GP     P+    + G  G  GP G PG  G  G  G PG  G  GP GS  F
Sbjct: 829 GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 49/114 (42%), Positives = 58/114 (50%), Gaps = 16/114 (14%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR 282
           P    D+G  I GD+         G  G PG +G  G  GPKG  G  G PGP G PG +
Sbjct: 816 PGFKGDMG--IKGDR---------GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864

Query: 283 GSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA---PGPRGSPGPPG 333
           G +G  G  P     +QG +G +G PG PG +G KG RG    PGPRG  GP G
Sbjct: 865 GKLGVPG-LPGYPG-RQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTG 916



 Score = 72.4 bits (176), Expect = 7e-13
 Identities = 36/71 (50%), Positives = 40/71 (56%), Gaps = 8/71 (11%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGS---PGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
            LPGP G  G +G  G  GP G    PG PG+PGPPG  G +GS GP GP  +  H     
Sbjct: 1505 LPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGH----- 1559

Query: 302  RGPVGPPGAPG 312
             GP GPPG PG
Sbjct: 1560 PGPPGPPGPPG 1570



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 41/98 (41%), Positives = 43/98 (43%), Gaps = 23/98 (23%)

Query: 249 PGLPGGQ--------GPPGSPGPKGSPGF--PGM--PGPPGQPGPRGSMGPMGPSPDLSH 296
           PG+P  Q        GP G  G KG P    PGM   GPPG  GP G  GP         
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGP--------- 482

Query: 297 IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              G  GP G  G PG  G  G  G PG  G PGPPG+
Sbjct: 483 --PGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGT 518



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 26/43 (60%), Positives = 27/43 (62%), Gaps = 3/43 (6%)

Query: 246  PGPPGLPGGQGPPG---SPGPKGSPGFPGMPGPPGQPGPRGSM 285
            PGPPGLPG  GP G   S GP G  G  G PGPPG PGP G +
Sbjct: 1530 PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEV 1572


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 50/104 (48%), Positives = 56/104 (53%), Gaps = 15/104 (14%)

Query: 245  LPGPPGLPGGQGPPGSPGPK--------GSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            LPG PG PG QGP G PG K        G+PG PG PG PG+ GPRG  G +GP  D   
Sbjct: 1425 LPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGF 1484

Query: 297  I-------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                    ++G RGP GP G+ G  G  G  GA GP G PGP G
Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTG 1528



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 45/87 (51%), Positives = 50/87 (57%), Gaps = 8/87 (9%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GP GL G  GPPG  GP G  G PG PGPPG  GPRG  G +G        ++G  GP G
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG--------EKGDEGPPG 1646

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
             PG PG+ G +G RGAPG RG  G  G
Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKG 1673



 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 47/89 (52%), Positives = 52/89 (58%), Gaps = 4/89 (4%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRGP 304
            PG  GLPG +G  G PGP G PG PG PG  G+PG  G  G P  P  D    ++G +G 
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED---GRKGEKGD 1861

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             G  G  GRDG KGERGAPG  G  GPPG
Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPG 1890



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 51/107 (47%), Positives = 56/107 (52%), Gaps = 20/107 (18%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGM------------PGPPGQPGPRGSMGPMGPSP 292
            LPG  G PG QGPPGS   KG  GFPG             PG PG PG +GS G  GP  
Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335

Query: 293  DLSHIKQGRRGPVGPPGAPGR------DGSKGERGAPGPRGSPGPPG 333
            D    ++G RGP G PGAPG+       G  G +G PGP G PGP G
Sbjct: 1336 DPG--ERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRG 1380



 Score = 89.0 bits (219), Expect = 7e-18
 Identities = 45/90 (50%), Positives = 50/90 (55%), Gaps = 1/90 (1%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMG-PMGPSPDLSHIKQGRRGP 304
            PG PG  G  G PG+PG KGSPG PG  G PG+ GPRG  G P  P   +     G  G 
Sbjct: 1307 PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGR 1366

Query: 305  VGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             G PG  G  G +G  G PGPRG PG PG+
Sbjct: 1367 KGDPGPSGPPGPRGPLGDPGPRGPPGLPGT 1396



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 51/103 (49%), Positives = 56/103 (54%), Gaps = 22/103 (21%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ--------------PGPRGSMGPMGPS 291
            PGPPG PG  GP G  GP G  G PG  GPPG+              PGP G +GP G S
Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQG-S 2243

Query: 292  PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            P L     G+ G  G PGAPGRDG+ G+    G RGSPG PGS
Sbjct: 2244 PGLP----GQVGETGKPGAPGRDGASGK---DGDRGSPGVPGS 2279



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 46/99 (46%), Positives = 50/99 (50%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            G+  L     + GP G PG QGP G PGP G  G PG PG PG  GP G  GP G   + 
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEP 2209

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                   RG  GP GA G  G  G  G  GP+GSPG PG
Sbjct: 2210 GETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPG 2248



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 45/92 (48%), Positives = 52/92 (56%), Gaps = 6/92 (6%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----PDLSHIKQ 299
            LPG PG PG QGP G PG  G  G  G PGP G+ G +G  GP GP+     P ++  + 
Sbjct: 1457 LPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAG-RP 1515

Query: 300  GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGP 331
            G +GP GPPG  GR G KGE G PG     GP
Sbjct: 1516 GAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP 1547



 Score = 87.0 bits (214), Expect = 3e-17
 Identities = 45/117 (38%), Positives = 55/117 (47%), Gaps = 29/117 (24%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPG-----------------------------MPGPP 276
            PGP G PG +GP G PGP+G PG PG                             +PG P
Sbjct: 1370 PGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP 1429

Query: 277  GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PGP+G +GP G   +    + G  G  G PG+PG  G +G  GA GP+G  G PG
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486



 Score = 86.3 bits (212), Expect = 5e-17
 Identities = 51/119 (42%), Positives = 57/119 (47%), Gaps = 13/119 (10%)

Query: 223  PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGP--------PGSPGPKGSPGFPGMPG 274
            P + A +G  + G K    +    GP G  G QG         PG PGPKG PG  G  G
Sbjct: 1539 PGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG 1598

Query: 275  PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G+ GP G  GP G   D      GR GP GP G  GRDG  GE+G  GP G PG PG
Sbjct: 1599 LTGRAGPPGDSGPPGEKGD-----PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 52/127 (40%), Positives = 59/127 (46%), Gaps = 42/127 (33%)

Query: 250  GLPGGQGPPGSPGPKGSPGFPGMPGPPG------QPGPRGSMGPMGPSPDLSHI----KQ 299
            G+PG  GPPG PG KG  G PG+PG PG      Q GPRG MG  GPS +        ++
Sbjct: 2374 GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGRE 2433

Query: 300  GRRGPVGPPGAPGR--------------------DGSKGERGAPG------------PRG 327
            G  GP+GPPG PG                      G +GERG PG            PRG
Sbjct: 2434 GIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRG 2493

Query: 328  SPGPPGS 334
              GPPGS
Sbjct: 2494 LTGPPGS 2500



 Score = 84.7 bits (208), Expect = 1e-16
 Identities = 44/91 (48%), Positives = 49/91 (53%), Gaps = 11/91 (12%)

Query: 247  GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
            GPPGL G +G PGS    GPKG  G PG+ G  G+PGPRG  G  G          G RG
Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPG--------LPGERG 2159

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              GP G PG  G +G  G  G  G PGPPG+
Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGA 2190



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 48/117 (41%), Positives = 55/117 (47%), Gaps = 18/117 (15%)

Query: 235  GDKVLASNTYLPGPPGLPG---GQGPPGSPGPKGS---------------PGFPGMPGPP 276
            G   LA     PG PGLPG   G G  G PG +G                PG PG PGPP
Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 277  GQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PGP+ S+   GP         G +G  G PG+ G  G KG+RG PG +G  G PG
Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 52/125 (41%), Positives = 59/125 (47%), Gaps = 43/125 (34%)

Query: 247  GPPGLPGGQGPP------GSPGPKGSPGFPGMPGP------------------------- 275
            G PGL G +GPP      G PGP G+PG  G  GP                         
Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224

Query: 276  ----PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSK---GERGAPGPRGS 328
                PG PGP G +GP G SP L     G+ G  G PGAPGRDG+    G+RG+PG  GS
Sbjct: 2225 AVGLPGPPGPSGLVGPQG-SPGL----PGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS 2279

Query: 329  PGPPG 333
            PG PG
Sbjct: 2280 PGLPG 2284



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 44/93 (47%), Positives = 52/93 (55%), Gaps = 7/93 (7%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP- 304
            PGP G  G +G  G+PG  G PG  G  G  G PGP GS+GP G  P+    ++G RGP 
Sbjct: 2691 PGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG--PEGLQGQKGERGPP 2748

Query: 305  ----VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                VG PG PG  G +GE+G PGP G  G  G
Sbjct: 2749 GERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 47/100 (47%), Positives = 52/100 (52%), Gaps = 12/100 (12%)

Query: 247  GPPGLPGGQGPPGSPG---PKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQ 299
            G PG+PG  G PG  G   PKG  GF G PGP G  G +G  G  G    P P  +    
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA 2721

Query: 300  GRRGP---VGPPGAPGRDGSKGERGAPGPR--GSPGPPGS 334
            G  GP   VGP G  G  G KGERG PG R  G+PG PG+
Sbjct: 2722 GPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGA 2761



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 43/99 (43%), Positives = 50/99 (50%), Gaps = 12/99 (12%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-----------PDL 294
            PGP G PG +GP G  G +G PG  G  G  G+PG  G  GP G +           P L
Sbjct: 1754 PGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGL 1813

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
               +QG  GP GPPG PG+ G  G+ G  G  G PG PG
Sbjct: 1814 RG-EQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPG 1851



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 49/103 (47%), Positives = 53/103 (51%), Gaps = 16/103 (15%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLS-----HIKQ 299
            GP G  G  G PG+PG +G  GF G PGP G PG RG  G  G    P L        K 
Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787

Query: 300  GRRGPVGPPGA------PGRD---GSKGERGAPGPRGSPGPPG 333
            G  GP GP GA      PGRD   G +GE+G PGP G PG PG
Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 48/115 (41%), Positives = 58/115 (50%), Gaps = 22/115 (19%)

Query: 240  ASNTYLP------GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPR-------GSMG 286
            +S ++LP      GP G  G QGPPG  GP G PG  G+ G  G PGP+       G  G
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 287  PMGPS--------PDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            P GPS        P +  +  GR G VG  G PG  G +GE+G  G +G  GPPG
Sbjct: 2026 PPGPSGLAGEPGKPGIPGL-PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPG 2079



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 46/103 (44%), Positives = 52/103 (50%), Gaps = 6/103 (5%)

Query: 235  GDKVLASNTYLPGPPGLPG-GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPD 293
            G++ L  +   PGP G PG   G  G PGP G  G PG PG PG PG  G +G  G   +
Sbjct: 2000 GERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGE 2059

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
                 +G RG  G  G  GRDG  G  G PGP G PGP  S D
Sbjct: 2060 -----RGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVD 2097



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 48/109 (44%), Positives = 54/109 (49%), Gaps = 13/109 (11%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GDK  A    LPG  GL G QG PG+ G  G PG PG  G PG  G +G +G MGP    
Sbjct: 2569 GDKGSAG---LPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625

Query: 295  SHI----------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                         ++G +G  GPPG PG  G KGE G PG  G  G PG
Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPG 2674



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 44/102 (43%), Positives = 50/102 (49%), Gaps = 14/102 (13%)

Query: 246  PGPPGLPGGQGPPGSP---------GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            PG PG  G  G PG+P         G +GSPG PG PG PG  GP+G  GP G       
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVV 2303

Query: 297  IKQGRRGPVGPPGA-----PGRDGSKGERGAPGPRGSPGPPG 333
               G +G  G PG       G  G+KG+RG PGPRG  G  G
Sbjct: 2304 GLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG 2345



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 41/90 (45%), Positives = 48/90 (53%), Gaps = 5/90 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G  G+PG +G  G PGP+G  G PG+PG  G  GP G  G  GP      +  G  G  G
Sbjct: 2129 GDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV--GGHGDPG 2186

Query: 307  PPGAPGRDGSKGERGAPGPRGSP---GPPG 333
            PPGAPG  G  G +G  G +G P   GPPG
Sbjct: 2187 PPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 48/113 (42%), Positives = 52/113 (46%), Gaps = 24/113 (21%)

Query: 245  LPGPPGLPGGQGP------------------PGSPGPKGSPGFPGMPGPPGQPGPRGSMG 286
            LPGP G PG +GP                  PG PG KG PG  G PGP G  G  G  G
Sbjct: 1330 LPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRG 1389

Query: 287  PMGPSPDLSHIKQGRRGPVGPPG------APGRDGSKGERGAPGPRGSPGPPG 333
            P G         +G RG  GPPG      APG  G  G  G+PGP+G  GPPG
Sbjct: 1390 PPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPG 1442



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 41/88 (46%), Positives = 43/88 (48%), Gaps = 5/88 (5%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  GL G  GPPG PG  G  G PG  GPPG    +G  G  G        + G  G  
Sbjct: 1259 PGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADG-----RPGSPGRA 1313

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PG PG  G KG  G PGPRG PG  G
Sbjct: 1314 GNPGTPGAPGLKGSPGLPGPRGDPGERG 1341



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 45/95 (47%), Positives = 48/95 (50%), Gaps = 16/95 (16%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQG 300
            G PGLPG  G  G PG  G  G  G PGP G+      PG  G  GP+GP         G
Sbjct: 2392 GLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGP--------PG 2443

Query: 301  RRGPVGPPGAPGRDGSKGERGA--PGPRGSPGPPG 333
              G VGPPGA G  G KG+ G   PGPRG  G PG
Sbjct: 2444 PPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478



 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 45/111 (40%), Positives = 54/111 (48%), Gaps = 10/111 (9%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMG 289
            + G++ +     L G  G  G  GPPG P   G KG  G PG+PG  G PG  G +GP G
Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683

Query: 290  -------PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                   P P     ++G RG  G  G PG  G+ G  G PGP GS GP G
Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 44/113 (38%), Positives = 51/113 (45%), Gaps = 14/113 (12%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            GD  L       G  G PG +GP G  G +G PG  G  G PG  GP+G  G  GP    
Sbjct: 1646 GDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP 1705

Query: 295  SHI--------------KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              +               +G+ GP GP G PG  G+ GERG  G RG PGP G
Sbjct: 1706 GRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 43/91 (47%), Positives = 48/91 (52%), Gaps = 9/91 (9%)

Query: 244  YLP-GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
            Y P G  G PG  G  G  GP G PG PG  G PG  GP GS    G        ++G  
Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKG--------ERGFP 1301

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G PG+PGR G+ G  GAPG +GSPG PG
Sbjct: 1302 GADGRPGSPGRAGNPGTPGAPGLKGSPGLPG 1332



 Score = 76.6 bits (187), Expect = 4e-14
 Identities = 45/110 (40%), Positives = 51/110 (46%), Gaps = 21/110 (19%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
            L G PG  G +G PG  G KG  G  G PG PG+ G +G+ GP G   D      G  GP
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGP 2381

Query: 305  VGPPGA------------------PGRDGSKGERGAPGP---RGSPGPPG 333
             GPPG                   PG+ G +GE G PGP   RG  GPPG
Sbjct: 2382 PGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 48/126 (38%), Positives = 55/126 (43%), Gaps = 32/126 (25%)

Query: 240  ASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP--------GPRGSMGPMGPS 291
            A +  LPG  G PG +GP G PGP G  G  G PG PG P        GP+G  G +GP+
Sbjct: 1503 AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPA 1562

Query: 292  -PDLSHIKQGRRGP-----------------------VGPPGAPGRDGSKGERGAPGPRG 327
             P  +   QG RGP                        G  G PG  G  GE+G PG  G
Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622

Query: 328  SPGPPG 333
             PGP G
Sbjct: 1623 PPGPVG 1628



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 43/102 (42%), Positives = 48/102 (47%), Gaps = 14/102 (13%)

Query: 246  PGPPGLPGG-------------QGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
            PGPPG PG               G  G  GP+G  G PG+PG PG+ G  G  GP GP  
Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758

Query: 293  DLS-HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            D       G +G  GPPG  GR G  G+ GA GP G  G  G
Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 44/97 (45%), Positives = 47/97 (48%), Gaps = 17/97 (17%)

Query: 246  PGPPGLPGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            PG PG PG  GP          G  GP G PG PG  G  G  G  G  GP+G   D   
Sbjct: 1618 PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD--- 1674

Query: 297  IKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              QG  G  G  G+PG  G KG+RG PGP   PGPPG
Sbjct: 1675 --QGDPGEDGRNGSPGSSGPKGDRGEPGP---PGPPG 1706



 Score = 75.5 bits (184), Expect = 8e-14
 Identities = 47/118 (39%), Positives = 53/118 (44%), Gaps = 18/118 (15%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP-----------GFPGMPGPPGQPGPRG 283
            GD+ L       G  G  G  G PG  G KG+P           G PG PGPPG PG +G
Sbjct: 2330 GDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKG 2389

Query: 284  SMG----PMGPSPDLSHIKQGRRGPVGPPGAPGR---DGSKGERGAPGPRGSPGPPGS 334
             +G    P  P       + G RG +G PG  G     G  G  G PGP G PGPPGS
Sbjct: 2390 DLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGS 2447



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 44/114 (38%), Positives = 49/114 (42%), Gaps = 23/114 (20%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G PG PG  G  G  G +GSPG PG PG PG  GP+G  GP G          G +G  G
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG 2313

Query: 307  PPGA-----PGRDGSKGERGAPGPRGS------------------PGPPGSFDF 337
             PG       G  G+KG+RG PGPRG                    G PG   F
Sbjct: 2314 APGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 48/123 (39%), Positives = 52/123 (42%), Gaps = 35/123 (28%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPG-------------QPGPRGSMGPMGPSPD 293
            G PG  G  G PGS GPKG  G PG PGPPG             +PG RG  GP GP  D
Sbjct: 1676 GDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGD 1735

Query: 294  LS-------HIKQGRRGPVGPPGAPGRDGSKGERG---------------APGPRGSPGP 331
                        +G RGP GP G PG  G  GE+G                PG  G  GP
Sbjct: 1736 PGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGP 1795

Query: 332  PGS 334
             G+
Sbjct: 1796 NGA 1798



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 48/108 (44%), Positives = 55/108 (50%), Gaps = 20/108 (18%)

Query: 246  PGPPG---LPGGQGPPGSPGPKGSP------GFPGMPGPPGQP--------GPRGSMGPM 288
            PGP G   LPG  G PG+ GP+G P      G  G PG PG P        GP+G  G +
Sbjct: 1500 PGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDV 1559

Query: 289  GPS-PDLSHIKQGRRGPVG--PPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+ P  +   QG RGP G   PG PG  G  G+RG  G  G  GPPG
Sbjct: 1560 GPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPG 1607



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 44/93 (47%), Positives = 49/93 (52%), Gaps = 7/93 (7%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP--SPDLSHIKQGRRG 303
            PGP G  G  G PG  G  G  G PG+ GP G PGP G  G  GP  +P L+    G +G
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG-PAGPQG 2201

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGS---PGPPG 333
            P G  G PG  G  G RG  GP G+   PGPPG
Sbjct: 2202 PSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPG 2233



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 46/110 (41%), Positives = 56/110 (50%), Gaps = 10/110 (9%)

Query: 234  TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP--GQPGPRGSMGPMG-P 290
            +G++ LA      G PG  G  GPPGS GP G+ G  G  G P  G PGPRG  G  G  
Sbjct: 2421 SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIR 2480

Query: 291  SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSP-------GPPG 333
              D    ++G RG  GPPG+ G  G KG+ G+ G +G         GPPG
Sbjct: 2481 GEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPG 2530



 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 45/120 (37%), Positives = 52/120 (43%), Gaps = 29/120 (24%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGP---------------------KGSPGFPGMP 273
            GD+     T   GPPG  G  G  G PG                      +G PG PG+P
Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651

Query: 274  GPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G  G+ G RG+ G  GP         G +G  G PG  GR+GS G  G  G RG PGPPG
Sbjct: 1652 GKAGERGLRGAPGVRGP--------VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPG 1703



 Score = 72.8 bits (177), Expect = 5e-13
 Identities = 42/90 (46%), Positives = 47/90 (52%), Gaps = 11/90 (12%)

Query: 247  GPPGLPGGQGPPGS---PGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
            GP GL G +GP G    PG KGS G PG  G  G PG RG +GP G        + G  G
Sbjct: 2542 GPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG--------QPGAAG 2593

Query: 304  PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
              G PG+PG+DG  G RG  G  G  GP G
Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623



 Score = 72.0 bits (175), Expect = 9e-13
 Identities = 40/88 (45%), Positives = 44/88 (50%), Gaps = 9/88 (10%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G  G  G +G  G  G +G+PG  G  GPPG PGP G  G   P         G  G  G
Sbjct: 1860 GDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP---------GVPGGTG 1910

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            P G  G  GSKGE+G PG RG  G PGS
Sbjct: 1911 PKGDRGETGSKGEQGLPGERGLRGEPGS 1938



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 40/93 (43%), Positives = 48/93 (51%), Gaps = 6/93 (6%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            GPPG PG  GPPG+ G KG  G PG+    G PGPRG  G  G   +    + G+ GP G
Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPGV----GLPGPRGERGEPGIRGEDG--RPGQEGPRG 2493

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLL 339
              G PG  G +GE+G  G  G  G  G    +L
Sbjct: 2494 LTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526



 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 43/105 (40%), Positives = 51/105 (48%), Gaps = 17/105 (16%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGM---------PGPPGQPGPRGSMGPMGPSPDLSH 296
            PGP G  G +G  G PGP GS G PG+          GPPG  G +G  G  G   D + 
Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544

Query: 297  I------KQGRRGPVGPPGAPGRDGSKGERGAPG--PRGSPGPPG 333
            +       +G +G VGP G  G  G +GERG PG    G PGP G
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589



 Score = 70.1 bits (170), Expect = 3e-12
 Identities = 47/130 (36%), Positives = 53/130 (40%), Gaps = 37/130 (28%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGF-------------------------PGMPGPPGQP 279
            +PG PGLPG  GP G PGP G+PG                          PG  G  G P
Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLP 2335

Query: 280  GPRGSMGPMG----PSPDLSHIKQGRRGP--------VGPPGAPGRDGSKGERGAPGPRG 327
            GPRG  G  G    P       ++G  GP        VG PG+PG  G  G +G  G  G
Sbjct: 2336 GPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPG 2395

Query: 328  SPGPPGSFDF 337
             PG PG   F
Sbjct: 2396 LPGAPGVVGF 2405



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 42/95 (44%), Positives = 48/95 (50%), Gaps = 11/95 (11%)

Query: 250  GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL-SHIKQGRRGP---- 304
            GLPG +G  G PG +G  G PG  GP G  GP GS G  G   D+ S   +G +G     
Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525

Query: 305  VGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333
            +GPPG  G  G  GERG        GPRG  G PG
Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPG 2560



 Score = 68.9 bits (167), Expect = 8e-12
 Identities = 43/103 (41%), Positives = 51/103 (49%), Gaps = 14/103 (13%)

Query: 245  LPGP------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI- 297
            LPGP      PG+ G  G PG  GP+G  G PG  G  G+ G  GS G  G   D + I 
Sbjct: 2467 LPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526

Query: 298  ----KQGRRGPVGPPGAPGRDGSKGER---GAPGPRGSPGPPG 333
                 +G +G +G  G  G DG KG R   G PG +GS G PG
Sbjct: 2527 GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPG 2569



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 45/125 (36%), Positives = 50/125 (40%), Gaps = 36/125 (28%)

Query: 245  LPGP--------PGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSM----------- 285
            LPGP        PG+PGG GP G  G  GS G  G+PG  G  G  GS+           
Sbjct: 1891 LPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAG 1950

Query: 286  -----------------GPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS 328
                             G   P P+     +G  G  GPPG  G  G  GERG  G RG 
Sbjct: 1951 IKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGD 2010

Query: 329  PGPPG 333
            PGP G
Sbjct: 2011 PGPQG 2015



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/107 (38%), Positives = 51/107 (47%), Gaps = 23/107 (21%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGF------------PGMPGPPGQPGPRGSMGPMGPSP 292
            +PG PG PG  G PG  G KG  GF             G  G  G+ G +G  GP G  P
Sbjct: 2594 IPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPG-RP 2652

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPR------GSPGPPG 333
             L+    G +G +G PG PG+ G+ G+ G  GP+      G PGP G
Sbjct: 2653 GLA----GHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695



 Score = 67.4 bits (163), Expect = 2e-11
 Identities = 44/106 (41%), Positives = 53/106 (50%), Gaps = 8/106 (7%)

Query: 233  ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-- 290
            + GDK    +  + GPPG  G +G  G  GP+G  G  G  G  G PG +GS G  G   
Sbjct: 2515 LKGDK--GDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572

Query: 291  SPDLSHIKQGRRGPVGPPGA---PGRDGSKGERGAPGPRGSPGPPG 333
            S  L  ++ G  GP G PGA   PG  GS G+ G PG RG  G  G
Sbjct: 2573 SAGLPGLR-GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 42/97 (43%), Positives = 47/97 (48%), Gaps = 7/97 (7%)

Query: 240  ASNTYLPGPPGLPG--GQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHI 297
            AS T  P P   P    +G  G PG  G  G  G PG PG PG  G+ GP GP    +  
Sbjct: 1236 ASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSAT-- 1293

Query: 298  KQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                +G  G PGA GR GS G  G PG  G+PG  GS
Sbjct: 1294 ---AKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGS 1327



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 44/131 (33%), Positives = 54/131 (41%), Gaps = 27/131 (20%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPG---------- 271
            L  +  D G  + G +       + G  G PG +GP G  GP GS G  G          
Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGL 2515

Query: 272  ---------MPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA 322
                     + GPPG  G +G MG  GP        +G  G  GP G  G  G KG +G 
Sbjct: 2516 KGDKGDSAVILGPPGPRGAKGDMGERGP--------RGLDGDKGPRGDNGDPGDKGSKGE 2567

Query: 323  PGPRGSPGPPG 333
            PG +GS G PG
Sbjct: 2568 PGDKGSAGLPG 2578



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 26/69 (37%), Positives = 32/69 (46%), Gaps = 11/69 (15%)

Query: 246  PGPPGLPGGQGPPGSPGPKG-----------SPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
            PGPPG  G +GP G  G KG           +PG PG PG  G+ G  G  GP G   + 
Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEA 2783

Query: 295  SHIKQGRRG 303
            +  +   RG
Sbjct: 2784 ALTEDDIRG 2792


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 47/92 (51%), Positives = 53/92 (57%), Gaps = 3/92 (3%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG---PSPDLSHIKQGR 301
           LPGPPG  G  G PG PGP+G  GFPG PG PG PG +G++G  G   P P       G 
Sbjct: 644 LPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL 703

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G +GPPG PGR G  G  G PG +G  G PG
Sbjct: 704 PGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG 735



 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 50/100 (50%), Positives = 56/100 (56%), Gaps = 2/100 (2%)

Query: 235  GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPD 293
            G+K    +   PG PG  G  G PG PGPKG PG  G PG PG PGP+GS+G MG P   
Sbjct: 963  GEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTP 1022

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  G  GP G PG PG  G+KGE+G  GP G  G PG
Sbjct: 1023 GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPG 1061



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 47/87 (54%), Positives = 53/87 (60%), Gaps = 5/87 (5%)

Query: 247  GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
            G  G PG  G PG PGPKG PGF GMPG  G PG  GS G MGP P +     G +GP G
Sbjct: 1266 GDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGP-PGV----PGFQGPKG 1320

Query: 307  PPGAPGRDGSKGERGAPGPRGSPGPPG 333
             PG  G  G +G++G PG +G PGPPG
Sbjct: 1321 LPGLQGIKGDQGDQGVPGAKGLPGPPG 1347



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 47/91 (51%), Positives = 55/91 (60%), Gaps = 7/91 (7%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ--PGPRGSMGPMGPSPDLSHIKQGRR 302
            L G PG+PG +G  G  GP G  G PG+PG PG    GP+G  GP G  P L     G  
Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQG-QPGL----PGLP 1250

Query: 303  GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GP+GPPG PG DG KG++G PG  G+PG PG
Sbjct: 1251 GPMGPPGLPGIDGVKGDKGNPGWPGAPGVPG 1281



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 50/105 (47%), Positives = 62/105 (59%), Gaps = 8/105 (7%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDL 294
           G++ L     + G PG+ G +GP G PG KG  G PG+PG  G  GP G+ G  G +P L
Sbjct: 49  GERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPG-NPGL 107

Query: 295 SHIKQGRRGPVGPPGAPGRDGSKGERGAPGP------RGSPGPPG 333
             I  G+ GP GPPG PG +G+KGERG  GP       G+PGPPG
Sbjct: 108 PGI-PGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPG 151



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 55/142 (38%), Positives = 61/142 (42%), Gaps = 30/142 (21%)

Query: 222 LPNNAADLGKYI--TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQP 279
           LP    D G+ +      +L      PG PG PG  G PG  GP G PGF G PGPPG P
Sbjct: 152 LPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPP 211

Query: 280 GPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRD------------------------- 314
           GP G  G MG S       +G +G  GPPG PG+                          
Sbjct: 212 GPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGM 271

Query: 315 ---GSKGERGAPGPRGSPGPPG 333
              G KGE G PGPRG PG  G
Sbjct: 272 PGVGEKGEPGKPGPRGKPGKDG 293



 Score = 88.6 bits (218), Expect = 9e-18
 Identities = 47/114 (41%), Positives = 57/114 (50%), Gaps = 25/114 (21%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG--------PSPDLSHI 297
            PG PG PG  G PG PG KG  GFPG  GP G PG +G  G +G           D+  +
Sbjct: 887  PGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSM 946

Query: 298  K-----QGRRGPVGP------------PGAPGRDGSKGERGAPGPRGSPGPPGS 334
            K     QG +G +GP            PG PG+DG  G+ G PGP+G PG  G+
Sbjct: 947  KGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGT 1000



 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 47/93 (50%), Positives = 50/93 (53%), Gaps = 14/93 (15%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PG PG +G PG  G KG  G PG PG PG PG  G  GP G        ++G  GP G
Sbjct: 278 GEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQG--------EKGEAGPPG 329

Query: 307 PPG---APGRDGSKGER---GAPGPRGSPGPPG 333
           PPG     G  G KGER   G PGPRG PGP G
Sbjct: 330 PPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKG 362



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 50/110 (45%), Positives = 57/110 (51%), Gaps = 27/110 (24%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGP---------RGSMGPMGPSPDLSH 296
           PG PG  G +GPPG+ G  G+PG PG+PG  G PGP         +G  GP+GP P L  
Sbjct: 84  PGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGP-PGL-- 140

Query: 297 IKQGRRGPVGPPGAPGRDGS-------------KGERGAPGPRGSPGPPG 333
              G  G  GPPG PG  G              KGERG PG  G+PGPPG
Sbjct: 141 --PGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPG 188



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 43/84 (51%), Positives = 50/84 (59%), Gaps = 5/84 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           G PGLPG +G  G PG  G PG PG+PG PGQ GP G  G  G      +  +G RGP+G
Sbjct: 82  GEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPG-----CNGTKGERGPLG 136

Query: 307 PPGAPGRDGSKGERGAPGPRGSPG 330
           PPG PG  G+ G  G PG +G PG
Sbjct: 137 PPGLPGFAGNPGPPGLPGMKGDPG 160



 Score = 85.9 bits (211), Expect = 6e-17
 Identities = 54/121 (44%), Positives = 61/121 (50%), Gaps = 36/121 (29%)

Query: 247  GPPGLPGGQGPPGSPG---------PKGSPGFPGMPGPPGQPGP-------RGSMGPMGP 290
            GPPG+PG QGP G PG          +G PG  G+PGPPG PGP        G  GP GP
Sbjct: 1308 GPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGP 1367

Query: 291  SPDLSHIKQGRRGP------------VGPPGAPGRDGSKGER------GAPGPRGSPGPP 332
             P L  + QG  GP             GPPG PG DG+ G++      G  GPRG PGPP
Sbjct: 1368 -PGLKGL-QGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPP 1425

Query: 333  G 333
            G
Sbjct: 1426 G 1426



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 48/105 (45%), Positives = 50/105 (47%), Gaps = 26/105 (24%)

Query: 246 PGPPGL---------------PGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
           PGPPG+               PG  GP G PGPKG PG PG PGPPG P P  +  P  P
Sbjct: 328 PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFP 387

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRD--GSKGERGAPGPRGSPGPPG 333
                    G RG  G  G PG    G  G  G PGP GSPGPPG
Sbjct: 388 ---------GERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG 423



 Score = 85.5 bits (210), Expect = 8e-17
 Identities = 48/102 (47%), Positives = 56/102 (54%), Gaps = 14/102 (13%)

Query: 246  PGPPGLP------GGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------P 292
            PG PGLP      GG G PG+PG KG PG PG  G PG PG +G+ G  G +       P
Sbjct: 1001 PGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIP 1060

Query: 293  DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
             L   ++G +G  G PG+PG  G KG  G PG  GSPG  GS
Sbjct: 1061 GLRG-EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGS 1101



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 48/101 (47%), Positives = 54/101 (53%), Gaps = 15/101 (14%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGP-MGPSPDLSHIKQGR 301
           PGPPG+PG  G  G  GP G PG PG    PGPPG PG +G  G  +G  P +  + +G 
Sbjct: 117 PGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGM--LLKGE 174

Query: 302 RG------PVGPPGAPGRDGSKGE---RGAPGPRGSPGPPG 333
           RG        GPPG PG  G  G     G PGP G PGPPG
Sbjct: 175 RGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 50/111 (45%), Positives = 55/111 (49%), Gaps = 21/111 (18%)

Query: 242 NTYLPGPPGLPGGQGPPGSP------------GPKGSPGFPGMPGPPGQPGPRGSMGP-M 288
           N  LPG PG  G  GPPG P            GP G PGF G PGPPG PG +G  G  +
Sbjct: 104 NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEIL 163

Query: 289 GPSPDLSHIKQGRR------GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G  P +  + +G R      G  GPPG PG  G  G  G  GP G PGPPG
Sbjct: 164 GHVPGM--LLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPG 212



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 49/107 (45%), Positives = 53/107 (49%), Gaps = 16/107 (14%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGF-----------PGMPGPPGQPGPRGSMGPMGPS 291
           T LPGP G  G  GPPGSPGP G PG+           PG  GPPG PG  G +G +G  
Sbjct: 401 TSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEK 460

Query: 292 PD-----LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
                  L     G RGP GP G PG  G  G+ GA G RG PG  G
Sbjct: 461 GQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDG 507



 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 45/92 (48%), Positives = 49/92 (53%), Gaps = 8/92 (8%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGPMGPSPDLSHIKQGR 301
           +PGP G  G QG PG  G  G PG PG    PG PG PG +G MG MG        + G 
Sbjct: 838 MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPG-----QPGS 892

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            GPVG PG PG  G  G  G+ GPRG PG  G
Sbjct: 893 PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKG 924



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 49/100 (49%), Positives = 53/100 (53%), Gaps = 13/100 (13%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPG-----------PPGQPGPRGSMGPMGPSPDL 294
            PG PG  G QG  G PGP+G PG PG PG           P GQPG  G  GPMGP P L
Sbjct: 1200 PGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP-PGL 1258

Query: 295  SHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
              I  G +G  G PG PG  G  G +G PG +G PG  GS
Sbjct: 1259 PGI-DGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS 1297



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 46/91 (50%), Positives = 51/91 (56%), Gaps = 5/91 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP---GQPGPRGSMGPMGPSPDLSHIKQGRR 302
           PG PG  G  G  G  G KGSPGFPG PG P   G+ GP+G  G  GP P    I  G  
Sbjct: 280 PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGP-PGPPGIVIG-T 337

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP+G  G  G  G+ G RG PGP+G PG PG
Sbjct: 338 GPLGEKGERGYPGTPGPRGEPGPKGFPGLPG 368



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 43/88 (48%), Positives = 47/88 (53%), Gaps = 5/88 (5%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVG 306
           GPPG P G GP G  G KG  GFPG PG PG PGP+G  G + P P       G  G  G
Sbjct: 601 GPPG-PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG----PPGAEGLPG 655

Query: 307 PPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            PG PG  G +G  G PG  G PG  G+
Sbjct: 656 SPGFPGPQGDRGFPGTPGRPGLPGEKGA 683



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 50/118 (42%), Positives = 57/118 (48%), Gaps = 24/118 (20%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGS------PGP-----------KGSPGFPGMPGP 275
           + G K    +  L G  G PGG G PGS      PGP           KG  GFPG PG 
Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGS 628

Query: 276 PGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           PG PGP+G  G + P P       G  G  G PG+PG  G +G+RG PG  G PG PG
Sbjct: 629 PGLPGPKGEPGKIVPLP-------GPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPG 679



 Score = 81.3 bits (199), Expect = 1e-15
 Identities = 47/102 (46%), Positives = 52/102 (50%), Gaps = 9/102 (8%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------PDLSHI 297
            LPGP G  GG G PG+PG KG PG PG  G PG PG +G+ G  G +       P L   
Sbjct: 1006 LPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGE 1065

Query: 298  K--QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
            K  QG  G  G PG  G  GS G  G PG  G  G PGS  +
Sbjct: 1066 KGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY 1107



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 48/98 (48%), Positives = 50/98 (51%), Gaps = 9/98 (9%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRGP 304
            PG PGLPG +G  G PG  G PG  G  G PG PGP G  G  G P  D      G +G 
Sbjct: 1108 PGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGE 1167

Query: 305  VGPPG--------APGRDGSKGERGAPGPRGSPGPPGS 334
             G PG        A G  GSKGE G PG  GSPG PGS
Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGS 1205



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 51/116 (43%), Positives = 57/116 (49%), Gaps = 13/116 (11%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGM------PGPPGQPGPRGSMGPM 288
           GD        + G  G PG  G PG PGPKGSPG  G+      PG  G PG RG  GP 
Sbjct: 544 GDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPP 603

Query: 289 GP---SPDLSHIKQGRRGPVGPPGAPGRDGSKGERG----APGPRGSPGPPGSFDF 337
           GP    P      +G+ G  G PG+PG  G KGE G     PGP G+ G PGS  F
Sbjct: 604 GPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGF 659



 Score = 80.5 bits (197), Expect = 3e-15
 Identities = 47/109 (43%), Positives = 56/109 (51%), Gaps = 11/109 (10%)

Query: 235  GDKVLASNTYLPGPPGLPGG----QGPPGSPGPKGSPGFPGM---PGPPGQPGPRGSMGP 287
            GD+ +     LPGPPG PG     +G PG PGP+G PG  G+   PGP GQ G  G +G 
Sbjct: 1332 GDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGI 1391

Query: 288  MGPSP----DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPP 332
             GP      D +  ++G  GP GP G  G  G  G  G PG  G PG P
Sbjct: 1392 PGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTP 1440



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 46/104 (44%), Positives = 52/104 (50%), Gaps = 15/104 (14%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS-------PDLSHIK 298
           PGPPG  G  G PG  GP G+PG PG  G PG PG +G  G  G         P L  I 
Sbjct: 692 PGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIP 751

Query: 299 --QGRRGPVGPPGAPGRDGS------KGERGAPGPRGSPGPPGS 334
              G +G +G PG PG  G+      +G RG PGP G PG  GS
Sbjct: 752 GTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGS 795



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 47/99 (47%), Positives = 53/99 (53%), Gaps = 16/99 (16%)

Query: 246  PGP---PGLPGGQGPPGSPGPKGS------PGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            PGP   PG+ G  G PG PGPKGS      PG PG  G PG PGP+GS G  G       
Sbjct: 989  PGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKG---- 1044

Query: 297  IKQGRRGPVGPP--GAPGRDGSKGERGAPGPRGSPGPPG 333
              +G +G  GPP  G PG  G KG++G  G  GSPG  G
Sbjct: 1045 -AKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKG 1082



 Score = 79.3 bits (194), Expect = 6e-15
 Identities = 42/89 (47%), Positives = 49/89 (55%), Gaps = 9/89 (10%)

Query: 246  PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
            PG  G PG  G PG  G KG PG  G+PG  G+ G  G+ GP GP+        G++G  
Sbjct: 1102 PGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA--------GQKGEP 1153

Query: 306  GPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
            G  G PG  G KGE G PG RG PG PG+
Sbjct: 1154 GSDGIPGSAGEKGEPGLPG-RGFPGFPGA 1181



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 41/93 (44%), Positives = 48/93 (51%), Gaps = 5/93 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP-----SPDLSHIKQG 300
           PGP G PG  G PG PG KG  G PG  G  G PGP+G+ G +G       P   +    
Sbjct: 479 PGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLR 538

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +G  G PG PG+ G  G  G+PG  G PG PG
Sbjct: 539 LKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPG 571



 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 49/109 (44%), Positives = 58/109 (53%), Gaps = 9/109 (8%)

Query: 235  GDKVLASNTYLPG---PPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPS 291
            GDK L     +PG     GLPG  GP G  G KG PG  G+PG  G+ G  G  G   P 
Sbjct: 1118 GDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG 1177

Query: 292  PDLSHIKQGRRGPVGPPG---APGRDGSKGER---GAPGPRGSPGPPGS 334
               +   +G +G VG PG   +PG  GSKGE+   G PGP+G PG PGS
Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGS 1226



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 47/106 (44%), Positives = 50/106 (47%), Gaps = 19/106 (17%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           LPGP G PG  G  G  GP G  GFPG  G  G PGP G  GP GP  D     +G+ G 
Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG-YGPAGPIGD-----KGQAGF 622

Query: 305 VGPPGAPGRDGSKGE-------------RGAPGPRGSPGPPGSFDF 337
            G PG+PG  G KGE              G PG  G PGP G   F
Sbjct: 623 PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGF 668



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 49/117 (41%), Positives = 54/117 (46%), Gaps = 29/117 (24%)

Query: 246 PGPPGLPG--------GQGPPGSPGPKGSPGFPG---MPGPPGQPGPRGSMGPMG----- 289
           PG PGLPG        G G PG PGPKG  G PG    PG PG+PG  G  G  G     
Sbjct: 672 PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQK 731

Query: 290 --PSPDLSHIK-----------QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             P   L  +K            G +G +G PG PG  G+ G  G  G RG PGPPG
Sbjct: 732 GEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 51/107 (47%), Positives = 57/107 (53%), Gaps = 19/107 (17%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP------------PGQPGPRGSMGPMGPSP 292
           LPG  GLPG  G PG+PG KGS G PG+PG              G+PGP G  G +G SP
Sbjct: 738 LPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG-SP 796

Query: 293 DLSHI-KQGRRGP---VGPPGAPGRDGSKGERGAPGPRG--SPGPPG 333
            +  I   G RGP    GPPG  G  G KGE+G PG  G   PGP G
Sbjct: 797 GVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG 843



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 46/95 (48%), Positives = 50/95 (52%), Gaps = 7/95 (7%)

Query: 246 PGPPGLPGGQGPPGSPG--PKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQ 299
           PGPPGLPG  G PG PG  P G+ G PG  GPPG  GP G  G  G    P  D+   K 
Sbjct: 784 PGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPK- 842

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
           G +G  G PG  G+ G  G  G  G  G PG PGS
Sbjct: 843 GDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGS 877



 Score = 76.3 bits (186), Expect = 5e-14
 Identities = 50/123 (40%), Positives = 55/123 (44%), Gaps = 34/123 (27%)

Query: 245 LPGPPGLPGGQGPPGSPGP-------------KGSPGFPGMPGP------------PGQP 279
           +PGP G PG  G PG+ G              KG PGFPG PG             PG P
Sbjct: 511 VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP 570

Query: 280 GPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRD-----GSKGERGAPGPRGSPG 330
           GP+GS G +G      P       G RG  GPPG PG       G KG+ G PG  GSPG
Sbjct: 571 GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPG 630

Query: 331 PPG 333
            PG
Sbjct: 631 LPG 633



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 43/96 (44%), Positives = 52/96 (54%), Gaps = 11/96 (11%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSHIKQG 300
           G PG+ G  G PG PG +G+PG PG PG  G+      PG  GS GP+G +P L     G
Sbjct: 849 GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG-APGL----PG 903

Query: 301 RRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFD 336
            +G  G PG+ G  G  G +G  G  G PG PGS D
Sbjct: 904 EKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMD 939



 Score = 75.9 bits (185), Expect = 6e-14
 Identities = 49/114 (42%), Positives = 56/114 (49%), Gaps = 17/114 (14%)

Query: 233  ITGDKVLASNTYLPGPPGL--PGGQGP---------PGSPGPKGSPGFPGMPGPPGQPGP 281
            + GDK         GPPG+  PG +G          PGSPG KG  G  G+PG PG PG 
Sbjct: 1039 LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGL 1098

Query: 282  RGSMGPMG--PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            +GS G +G   SP L     G +G  G PG  G  G KGE G PG  G  GP G
Sbjct: 1099 KGSPGSVGYPGSPGL----PGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAG 1148



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 48/130 (36%), Positives = 55/130 (42%), Gaps = 30/130 (23%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQ--------GPPGSPGPKGSPGFPGMPG 274
           P     +G    G K    +  + GPPG+PG             G  G KG PGF GMPG
Sbjct: 214 PGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPG 273

Query: 275 -----PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGS- 328
                 PG+PGPRG  G           K G +G  G PG PG  G  G  G  GP+G  
Sbjct: 274 VGEKGEPGKPGPRGKPG-----------KDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEK 322

Query: 329 -----PGPPG 333
                PGPPG
Sbjct: 323 GEAGPPGPPG 332



 Score = 74.7 bits (182), Expect = 1e-13
 Identities = 50/115 (43%), Positives = 56/115 (48%), Gaps = 27/115 (23%)

Query: 245 LPGPPGLPGGQGPPGS--PGPKGSPGFPGMPGPPGQ------PGPRGSMGPMGPSPDLSH 296
           LPG PG+ G +G PG   PG KG PG PG+PG PG+      PG  G  G +GP P L  
Sbjct: 721 LPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP-PGL-- 777

Query: 297 IKQGRRGPVGPPGAPGRDGSKGE--------------RGAPGPRGSPGPPGSFDF 337
             QG RG  GPPG PG  GS G               +G PG  G PG  G   F
Sbjct: 778 --QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGF 830



 Score = 73.9 bits (180), Expect = 2e-13
 Identities = 51/123 (41%), Positives = 57/123 (46%), Gaps = 25/123 (20%)

Query: 233  ITGDKVLASNTYLPGPPGL------------PGGQGPPGSPGP---KGSPGFPGMPGPPG 277
            + GDK    +  LPG PG              G QG  G  GP   KGS G PG PG PG
Sbjct: 922  LKGDK---GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPG 978

Query: 278  QPGPRGSMGPMGP--SPDLSHIK-----QGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
            + G  G  G  GP   P +S         G +G VG  G PG  G KG  G PGP+GSPG
Sbjct: 979  KDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038

Query: 331  PPG 333
             PG
Sbjct: 1039 LPG 1041



 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 47/115 (40%), Positives = 51/115 (44%), Gaps = 24/115 (20%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSP----------GFPGMPGPPGQPGPRGS 284
           GD+ L     + G PG  G  G  G PG KG P          G  G PG PGQPG  G 
Sbjct: 498 GDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGR 557

Query: 285 MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGA------PGPRGSPGPPG 333
            G  G        + G  G  GP G+PG  G KGERG       PG RG  GPPG
Sbjct: 558 AGSPG--------RDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG 604



 Score = 67.0 bits (162), Expect = 3e-11
 Identities = 36/74 (48%), Positives = 38/74 (51%), Gaps = 10/74 (13%)

Query: 245  LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMG----PSPDLSHIKQG 300
            LPGP G  G  G  G PGP G PGF G PG  G+ GP G  GP G    P PD      G
Sbjct: 1376 LPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPD------G 1429

Query: 301  RRGPVGPPGAPGRD 314
              G +GPPG P  D
Sbjct: 1430 LPGSMGPPGTPSVD 1443



 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 29/55 (52%), Positives = 33/55 (60%), Gaps = 4/55 (7%)

Query: 245  LPGPPGLPGGQGPPGSP---GPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSH 296
            +PGPPG+PG  G PG     GP G  G  G PGPPG  G  GSMGP G +P + H
Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPG-TPSVDH 1444



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 20/76 (26%)

Query: 259 GSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKG 318
           G  G KG  G PG+ G  G PG                     +GP GP G PG+ G  G
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPG--------------------MQGPEGPQGPPGQKGDTG 82

Query: 319 ERGAPGPRGSPGPPGS 334
           E G PG +G+ GPPG+
Sbjct: 83  EPGLPGTKGTRGPPGA 98



 Score = 33.9 bits (76), Expect = 0.27
 Identities = 16/38 (42%), Positives = 21/38 (55%)

Query: 296 HIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           H  +G++G  G PG  G  G  G +G  GP+G PG  G
Sbjct: 42  HGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKG 79


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 56/141 (39%), Positives = 62/141 (43%), Gaps = 39/141 (27%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF------------------------P 270
           G   LA    +PG  GLPG  GPPG  GPKG PGF                        P
Sbjct: 397 GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQP 456

Query: 271 GMPGPPGQPGPRGSMGPMGPS--PDLSHI-------------KQGRRGPVGPPGAPGRDG 315
           G+ GP G PG +G  GP+GP   P L                + G  GP GPPG PG  G
Sbjct: 457 GLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPG 516

Query: 316 SKGERGAPGPRGSPGPPGSFD 336
             G  G PGP G PG PG+FD
Sbjct: 517 ITGPPGPPGPPGPPGAPGAFD 537



 Score = 92.0 bits (227), Expect = 8e-19
 Identities = 49/92 (53%), Positives = 53/92 (57%), Gaps = 7/92 (7%)

Query: 248 PPGLPGGQGPPGSPGPKGSPGFPGMPGPP--GQPGPRGSMGPMGPSPDLSHIKQ----GR 301
           P  L G  GPPG PGP+G PG PG PG P  G+PG  G  GP GP P  S + +    G 
Sbjct: 72  PMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGP-PGFSRMGKAGPPGL 130

Query: 302 RGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G VGPPG PG  G  G RG  G RG PGPPG
Sbjct: 131 PGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPG 162



 Score = 90.1 bits (222), Expect = 3e-18
 Identities = 48/104 (46%), Positives = 56/104 (53%), Gaps = 15/104 (14%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGP-----PGQPGPRGSMGPMG---------- 289
           +PG  GLPG QGP G+ G  G+ G PG+ GP     PG PGP+G  GP G          
Sbjct: 282 VPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGE 341

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P  D    +QG +G  GPPG PG  G  G RG PGP+G  GP G
Sbjct: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG 385



 Score = 89.7 bits (221), Expect = 4e-18
 Identities = 46/88 (52%), Positives = 50/88 (56%), Gaps = 5/88 (5%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  G PG QGP G  GP G PG  G+PG  G PGP+G  GP GP P +     G RG  
Sbjct: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGP-PGV----PGIRGDQ 396

Query: 306 GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP G  G+ G  GERG PG  G PGP G
Sbjct: 397 GPSGLAGKPGVPGERGLPGAHGPPGPTG 424



 Score = 89.4 bits (220), Expect = 5e-18
 Identities = 51/112 (45%), Positives = 57/112 (50%), Gaps = 33/112 (29%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGF------------PGMPGP-----PGQPGPRGSMGPMG 289
           GPPGLPG  GPPG PG +G PG             PG+PGP     PG+PG +G  GP G
Sbjct: 126 GPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPG 185

Query: 290 PSPDLSHIKQGRRGPVGPPGAPGRDGSKGER--------GAPGPRGSPGPPG 333
                    QG  GP G PG PG  G KG+         GAPG  G+PGPPG
Sbjct: 186 --------FQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPG 229



 Score = 83.6 bits (205), Expect = 3e-16
 Identities = 47/103 (45%), Positives = 51/103 (49%), Gaps = 17/103 (16%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGS-----------PGFPGMPGPPGQPGPRGSMGPMG---P 290
           +PGPPG  G  GP G PGP G            PG PG PG  G PGP G  GP G   P
Sbjct: 180 VPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKP 239

Query: 291 SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
             D      G +G  GPPG P   G +GE GA GP+G PG  G
Sbjct: 240 GLDGLPGAPGDKGESGPPGVP---GPRGEPGAVGPKGPPGVDG 279



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 49/102 (48%), Positives = 55/102 (53%), Gaps = 15/102 (14%)

Query: 246 PGPPGLPGGQGP--PGSPGPK---GSPGFPGMPGPPGQPGPRGSMGPMGPS----PDLSH 296
           PGPPGLPG  G   PG PG +   G PGF G PGP G+PGP G  G  G +    P L  
Sbjct: 158 PGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPG 217

Query: 297 IKQGRRGPVGPPGAP-----GRDGSKGERGAPGPRGSPGPPG 333
              G+ G  GPPG P     G+ G  G  GAPG +G  GPPG
Sbjct: 218 -APGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPG 258



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 48/102 (47%), Positives = 52/102 (50%), Gaps = 15/102 (14%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQ-----PGPRGSMGPMGPSPDLSHIKQ 299
           LPG PG  G  GPPG PGP+G PG  G  GPPG      PG  G  GP GPS      + 
Sbjct: 244 LPGAPGDKGESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKG--EP 301

Query: 300 GRRGP---VGP-----PGAPGRDGSKGERGAPGPRGSPGPPG 333
           G RGP   +GP     PG PG  G +G  G PG  G  G PG
Sbjct: 302 GTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEPG 343



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 51/112 (45%), Positives = 59/112 (52%), Gaps = 25/112 (22%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPG--------MPGPPG------QPGPRGSMGPMGPS- 291
           GPPG+PG +G PG+ GPKG PG  G        +PGP G      +PG RG  G +GP+ 
Sbjct: 255 GPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTG 314

Query: 292 ---PDLSHIKQGRRGPVGPPGA------PGRDGSKGERGAPGPRGSPGPPGS 334
              P L   K G RGP G PG       PG DG  GE+G  G  G PG PGS
Sbjct: 315 YGMPGLPGPK-GDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGS 365



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 45/89 (50%), Positives = 47/89 (52%), Gaps = 5/89 (5%)

Query: 245 LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGP 304
           L GPPGLPG  G PG  GP G  G  G  GPPG PG RG  GP G +      K G  G 
Sbjct: 356 LGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGLAG-----KPGVPGE 410

Query: 305 VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
            G PGA G  G  G +G PG  G PG PG
Sbjct: 411 RGLPGAHGPPGPTGPKGEPGFTGRPGGPG 439



 Score = 79.7 bits (195), Expect = 4e-15
 Identities = 47/107 (43%), Positives = 55/107 (51%), Gaps = 17/107 (15%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKG-----SPGFPGMPGPP---GQPGPRGSMG 286
           G   L     + G  GL G  GPPG PGP G      PG  G+PGPP   G+PGP+G  G
Sbjct: 138 GQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGEPG 197

Query: 287 PMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P G         +G +G  G  G PG  G+ G+ GAPGP G PGP G
Sbjct: 198 PPG--------DRGLKGDNG-VGQPGLPGAPGQGGAPGPPGLPGPAG 235



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 44/101 (43%), Positives = 47/101 (46%), Gaps = 5/101 (4%)

Query: 233 ITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           + GD+        PG  G  G  GPPG PG  G PG  G PGP G+ GP G  G  G   
Sbjct: 335 LLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRG 394

Query: 293 DLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           D     QG  G  G PG PG  G  G  G PGP G  G PG
Sbjct: 395 D-----QGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPG 430



 Score = 78.2 bits (191), Expect = 1e-14
 Identities = 52/123 (42%), Positives = 62/123 (50%), Gaps = 9/123 (7%)

Query: 223 PNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGF---PGMPGPPGQ- 278
           P  A  LG+   GD  L     L GP G+PG QGP G  GP+G PG    PG+PGPPG+ 
Sbjct: 438 PGVAGALGQ--KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEG 495

Query: 279 -PGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDF 337
             G  G+ GP GP P +     G  GP GPPG PG  G+ G     G  G   P G  + 
Sbjct: 496 RAGEPGTAGPTGP-PGVPG-SPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEG 553

Query: 338 LLL 340
            +L
Sbjct: 554 AVL 556



 Score = 77.0 bits (188), Expect = 3e-14
 Identities = 50/113 (44%), Positives = 57/113 (50%), Gaps = 25/113 (22%)

Query: 246 PGPPGLPG-------GQ-GPPGSPGPKGSPGFPGMPGP-----------PGQPGPRGSMG 286
           PGPPG  G       GQ G PG+PG  G+PG PG+PGP           PG PG +G  G
Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG 255

Query: 287 PMG-PSPDLSHIKQGRRGP-----VGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P G P P       G +GP     VG PGA G  G +G  GA G  G+ GPPG
Sbjct: 256 PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPG 308



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 24/57 (42%), Positives = 27/57 (47%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRG 303
           GP G PG  G PG  GP G PG PG PG PG     G  G   P+  +     G+ G
Sbjct: 504 GPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGG 560



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 17/96 (17%)

Query: 254 GQGPPGSPG--PKGSPGF-------PGMPGPPGQPGPRGSMGPMG-PSPDLSHIKQGRRG 303
           G GP  S G    G+ G+       P   GP G P   G    +  P P L    +G  G
Sbjct: 21  GCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDLKGEPG 80

Query: 304 PV------GPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P       GPPG PG  G  G  G PG  G PGP G
Sbjct: 81  PPGKPGPRGPPGPPGFPGKPG-MGKPGLHGQPGPAG 115



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 234 TGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSP 292
           TG   +  +  + GPPG PG  GPPG+PG     G  G+  P G  G  G++   G  P
Sbjct: 506 TGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNG--GVEGAVLGKGGKP 562


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 95.5 bits (236), Expect = 8e-20
 Identities = 60/150 (40%), Positives = 75/150 (50%), Gaps = 13/150 (8%)

Query: 194 KAGTCCATCKEFYQMKQTVLQLKQKIALL---PNNAADLGKY-ITGDKVLASNTYLPGPP 249
           K G    + +E +   +  L ++Q+   L   P    D+G     GD+       +PGP 
Sbjct: 537 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL 596

Query: 250 GLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR------G 303
           G PG QGP G    KGS G PGM GP GQ G  G MGP G +      ++G R      G
Sbjct: 597 GHPGPQGPKGQ---KGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG 653

Query: 304 PVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           P GPPG PG  G KG  G+PGP+G PGP G
Sbjct: 654 PHGPPGVPGSVGPKGSSGSPGPQGPPGPVG 683



 Score = 92.8 bits (229), Expect = 5e-19
 Identities = 56/136 (41%), Positives = 64/136 (47%), Gaps = 40/136 (29%)

Query: 230 GKYITGDKVLASNTYLPGPPGLPGGQGPPG---SPGPKGSPGFPG------MPGPPGQPG 280
           GK +T +   +S   +PGPPG PG  GPPG   +PGP G  G PG      + GPPG PG
Sbjct: 806 GKIVTSEG--SSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPG 863

Query: 281 PRGSMGPMGPSPDLSHIKQGRRGPVG-----------------------PPGAPGRDGSK 317
           PRG  GP  P P       G RGP G                       PPG PG  G K
Sbjct: 864 PRGPPGPSIPGPP------GPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK 917

Query: 318 GERGAPGPRGSPGPPG 333
           G++G PGPRG  G  G
Sbjct: 918 GDQGPPGPRGHQGEQG 933



 Score = 92.4 bits (228), Expect = 6e-19
 Identities = 55/127 (43%), Positives = 69/127 (54%), Gaps = 10/127 (7%)

Query: 218 KIALLPNNAADLGKYITGDKVLAS-NTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPP 276
           KI L  ++  +L  ++    ++   N  L G PG  G  G PG  G +G PG PG+PGP 
Sbjct: 537 KIGLHSDSQEELWMFVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL 596

Query: 277 GQPGPRGSMGPMG----PSPDLSHIKQGRRGPVGPPGAPGRDGS--KGERGA---PGPRG 327
           G PGP+G  G  G    P  +    ++GR GP+GP G  G  GS  KGERGA   PGP G
Sbjct: 597 GHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHG 656

Query: 328 SPGPPGS 334
            PG PGS
Sbjct: 657 PPGVPGS 663



 Score = 82.8 bits (203), Expect = 5e-16
 Identities = 53/139 (38%), Positives = 58/139 (41%), Gaps = 50/139 (35%)

Query: 246  PGP--PGLPGGQGPPGS--PGPKGSPG---------FPGMPGPPGQPGPRGSMGPMGP-- 290
            PGP  PG PG +GPPG   PGP G PG           G PGPPG PGP+G  GP GP  
Sbjct: 868  PGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPKGDQGPPGPRG 927

Query: 291  -----------SPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPG--------------- 324
                       +   S      +GP GPPG  G  G KG+ G PG               
Sbjct: 928  HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSS 987

Query: 325  ---------PRGSPGPPGS 334
                     P G PGPPGS
Sbjct: 988  TMYVSGPPGPPGPPGPPGS 1006



 Score = 82.0 bits (201), Expect = 9e-16
 Identities = 42/94 (44%), Positives = 50/94 (53%), Gaps = 7/94 (7%)

Query: 247 GPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ------- 299
           GPPG  G QG  G  G  G PG  G+PG  G+PG +G+MGP GP        +       
Sbjct: 704 GPPGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMP 763

Query: 300 GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           G RGP GP G PG+ G  G +G  G  G+PG PG
Sbjct: 764 GIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPG 797



 Score = 81.6 bits (200), Expect = 1e-15
 Identities = 46/105 (43%), Positives = 55/105 (52%), Gaps = 8/105 (7%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGS---PGPKGSPG---FPGMPGPPGQPGPRGSMGPM 288
           G++  A      GPPG+PG  GP GS   PGP+G PG     G+ G  G PG +G  GPM
Sbjct: 644 GERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGLPGVKGDKGPM 703

Query: 289 GPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPG 333
           GP        QG +GP G  G PG  G  G  G PG +G+ GP G
Sbjct: 704 GPPGPKG--DQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAG 746



 Score = 80.1 bits (196), Expect = 3e-15
 Identities = 45/101 (44%), Positives = 49/101 (48%), Gaps = 20/101 (19%)

Query: 246 PGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRRGPV 305
           PG  G  G  GP G  GP+G  G  GMPG  G PGP G  G  G +        G +GP 
Sbjct: 736 PGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT--------GPQGPQ 787

Query: 306 GPPGAPGRDGSKGERGAPGP------------RGSPGPPGS 334
           G PG PGR G KGE GAPG              G PGPPG+
Sbjct: 788 GLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGA 828



 Score = 79.0 bits (193), Expect = 7e-15
 Identities = 46/123 (37%), Positives = 52/123 (42%), Gaps = 32/123 (26%)

Query: 235 GDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPG-------------------- 274
           G++ L     + GPPG  G  G PG  GP+G  G PG PG                    
Sbjct: 755 GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814

Query: 275 ----PPGQPGPRGSMGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRGSPG 330
                PG PGP G+MGP GP         G  GP GP G PG       +G PGP G  G
Sbjct: 815 SMLTVPGPPGPPGAMGPPGP--------PGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRG 866

Query: 331 PPG 333
           PPG
Sbjct: 867 PPG 869



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 53/163 (32%), Positives = 62/163 (38%), Gaps = 55/163 (33%)

Query: 222  LPNNAADLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPG------- 274
            LP      G +++  +   S    PGPPG PG +G  G PGP+G  G  G+PG       
Sbjct: 886  LPGPPGPPGSFLSNSETFLSGP--PGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSS 943

Query: 275  --------PPGQPGPRGSMG-------------PMGPSPDLSHIKQGRRGPVGPPGAPGR 313
                    PPG PGP+G  G             P GPS   S       GP GPPG PG 
Sbjct: 944  SFGLNLQGPPGPPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGP 1003

Query: 314  DGS-------------------------KGERGAPGPRGSPGP 331
             GS                          G +G PGP G PGP
Sbjct: 1004 PGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046



 Score = 75.1 bits (183), Expect = 1e-13
 Identities = 42/98 (42%), Positives = 49/98 (50%), Gaps = 2/98 (2%)

Query: 243 TYLPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQGRR 302
           T +PG  G PG  G PG PG  G  G  G+PG PG+PG +G   P  P   ++       
Sbjct: 760 TGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGE--PGAPGKIVTSEGSSML 817

Query: 303 GPVGPPGAPGRDGSKGERGAPGPRGSPGPPGSFDFLLL 340
              GPPG PG  G  G  GAPGP G  G PG  + L L
Sbjct: 818 TVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNL 855



 Score = 65.5 bits (158), Expect = 8e-11
 Identities = 35/94 (37%), Positives = 43/94 (45%), Gaps = 32/94 (34%)

Query: 255  QGPPGSPGPKGSPG---------------------FPGMPGPPGQPGPRGSMGPMGPSPD 293
            QGPPG PGP+G PG                     +  + GPPGQ G  G+ GP      
Sbjct: 1398 QGPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGP------ 1451

Query: 294  LSHIKQGRRGPVGPPGAPGRDGSKGERGAPGPRG 327
                 +G RGP GPPG PG  G +G +G  G +G
Sbjct: 1452 -----KGDRGPAGPPGHPGPPGPRGHKGEKGDKG 1480



 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 45/134 (33%), Positives = 47/134 (35%), Gaps = 66/134 (49%)

Query: 246  PGPPGLPGGQ-----------------GPPGSPGPKGSPG-------------------- 268
            PGPPGLPG                   GPPG PGP G PG                    
Sbjct: 1151 PGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGL 1210

Query: 269  --FPGMPGPPGQPGPRGSMGPMGP---------------------SPDLSHIKQGRRGPV 305
               PG PGPPG PGPRG  G  G                      SPD+      R   V
Sbjct: 1211 SFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDV------RSFIV 1264

Query: 306  GPPGAPGRDGSKGE 319
            GPPG PG  G  G+
Sbjct: 1265 GPPGPPGPQGPPGD 1278



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 43/131 (32%), Positives = 44/131 (33%), Gaps = 63/131 (48%)

Query: 245  LPGPPGLPGGQ--------------------GPPGSPGPKGSPG---------------- 268
            LPGPPG PG                      GPPG PGP G PG                
Sbjct: 1147 LPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLH 1206

Query: 269  ------FPGMPGPPGQPGPRGSMGPMG---------------------PSPDLSHIKQGR 301
                   PG PGPPG PGPRG  G  G                      SPD+     G 
Sbjct: 1207 TAGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENSDSFRSELISYLTSPDVRSFIVGP 1266

Query: 302  RGPVGPPGAPG 312
             GP GP G PG
Sbjct: 1267 PGPPGPQGPPG 1277



 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 39/99 (39%), Positives = 45/99 (45%), Gaps = 24/99 (24%)

Query: 250  GLPGGQGPPGSPGP---------KGSPGFPGMPGPPGQPGPRGSMGPMGPSPDLSHIKQ- 299
            GLPG  GPPG PG          +GS  F G+ GPPG PGP G  G +  S  +  +   
Sbjct: 1146 GLPGPPGPPGLPGTSYEELLSLLRGSE-FRGIVGPPGPPGPPGIPGNVWSSISVEDLSSY 1204

Query: 300  ----GRRGPVGPPGAPGRDGSKGERGAPGPRGSPGPPGS 334
                G     GPPG PG          PGPRG PG  G+
Sbjct: 1205 LHTAGLSFIPGPPGPPG---------PPGPRGPPGVSGA 1234



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 31/70 (44%), Positives = 35/70 (50%), Gaps = 10/70 (14%)

Query: 274  GPPGQPGPRGSMGPM-------GPSPDLSHIKQ---GRRGPVGPPGAPGRDGSKGERGAP 323
            GPPGQPGP+G  G           + DL    Q     +GP G  G  G  G KG+RG  
Sbjct: 1399 GPPGQPGPQGPPGISKVFSAYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA 1458

Query: 324  GPRGSPGPPG 333
            GP G PGPPG
Sbjct: 1459 GPPGHPGPPG 1468



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 31/72 (43%), Positives = 38/72 (52%), Gaps = 5/72 (6%)

Query: 233  ITGDKVLASNTY--LPGPPGLPGGQGPPGSPGPKGSPGFPGMPGPPGQPGPRGSMGPMGP 290
            +T D +    TY  + GPPG    +G  G+PGPKG  G  G PG PG PGPRG  G  G 
Sbjct: 1422 VTADLMDFFQTYGAIQGPPGQ---KGEMGTPGPKGDRGPAGPPGHPGPPGPRGHKGEKGD 1478

Query: 291  SPDLSHIKQGRR 302
              D  +  + RR
Sbjct: 1479 KGDQVYAGRRRR 1490



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 45/132 (34%), Positives = 47/132 (35%), Gaps = 60/132 (45%)

Query: 251  LPGGQGPPGSPGPKG-------------------------SPGFPGMPGPPGQPGP---- 281
            L G +GPPG PG  G                         S G PG PGPPG PG     
Sbjct: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163

Query: 282  -----RGS--MGPMGPSPDLSHIKQGRRGPVGPPGAPGRDGSK-------------GERG 321
                 RGS   G +GP            GP GPPG PG   S              G   
Sbjct: 1164 LLSLLRGSEFRGIVGPP-----------GPPGPPGIPGNVWSSISVEDLSSYLHTAGLSF 1212

Query: 322  APGPRGSPGPPG 333
             PGP G PGPPG
Sbjct: 1213 IPGPPGPPGPPG 1224



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 52/185 (28%), Positives = 63/185 (34%), Gaps = 84/185 (45%)

Query: 240  ASNTYLPGPPGLPGGQGPPGSPGPKGSP-------------------GFPGMPGPPGQPG 280
            +S  Y+ GPPG PG  GPPGS    G                     G  G PGPPG PG
Sbjct: 986  SSTMYVSGPPGPPGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPG 1045

Query: 281  PRGSMGPMGPSPDLS----------------------------------------HIKQG 300
            P  ++   G + D S                                        +++Q 
Sbjct: 1046 PVTTI--TGETFDYSELASHVVSYLRTSGYGVSLFSSSISSEDILAVLQRDDVRQYLRQY 1103

Query: 301  RRGPVGPPGAPGRDG---------------------SKG-ERGAPGPRGSPGPPG-SFDF 337
              GP GPPG PG  G                     S G   G PGP G PG PG S++ 
Sbjct: 1104 LMGPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEE 1163

Query: 338  LLLML 342
            LL +L
Sbjct: 1164 LLSLL 1168



 Score = 46.2 bits (108), Expect = 5e-05
 Identities = 48/158 (30%), Positives = 58/158 (36%), Gaps = 60/158 (37%)

Query: 228  DLGKYITGDKVLASNTYLPGPPGLPGGQGPPGSPGPKGSPGFPG---------------- 271
            DL  Y+      A  +++PGPPG      PPG PGP+G PG  G                
Sbjct: 1200 DLSSYLH----TAGLSFIPGPPG------PPGPPGPRGPPGVSGALATYAAENSDSFRSE 1249

Query: 272  ----MPGPP------GQPGPRGSMGPMGPSPDL-------------SHIKQGRRGPV--- 305
                +  P       G PGP G  GP G S  L             SH    RRG     
Sbjct: 1250 LISYLTSPDVRSFIVGPPGPPGPQGPPGDSRLLSTDASHSRGSSSSSHSSSVRRGSSYSS 1309

Query: 306  ------GPPGAPGRDGSKGE-RGAPGPRGSP-GPPGSF 335
                  G  G+ G  G+ GE  G  GP G+  GP G +
Sbjct: 1310 SMSTGGGGAGSLGAGGAFGEAAGDRGPYGTDIGPGGGY 1347


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.140    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,516,479
Number of Sequences: 37866
Number of extensions: 1769500
Number of successful extensions: 65652
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 574
Number of HSP's successfully gapped in prelim test: 1056
Number of HSP's that attempted gapping in prelim test: 10814
Number of HSP's gapped (non-prelim): 12685
length of query: 406
length of database: 18,247,518
effective HSP length: 105
effective length of query: 301
effective length of database: 14,271,588
effective search space: 4295747988
effective search space used: 4295747988
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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