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Search of human proteins with 38327612
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
(278 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 542 e-154
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 497 e-141
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 497 e-141
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 120 1e-27
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 113 2e-25
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 111 6e-25
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 99 5e-21
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 95 6e-20
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 90 2e-18
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 90 2e-18
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 90 2e-18
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 86 4e-17
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 86 4e-17
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 86 4e-17
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 81 9e-16
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 81 9e-16
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 79 6e-15
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 79 6e-15
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 79 6e-15
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 69 6e-12
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 60 2e-09
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 58 8e-09
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 57 2e-08
gi|203098098 shroom family member 3 protein [Homo sapiens] 55 9e-08
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 54 1e-07
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 54 1e-07
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 54 1e-07
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 54 2e-07
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 52 6e-07
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 50 2e-06
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 542 bits (1397), Expect = e-154
Identities = 278/278 (100%), Positives = 278/278 (100%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
Query: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS
Sbjct: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
Query: 241 SFRLLQEALEAEERGTRLCASRRAGTATPAATPVPTVG 278
SFRLLQEALEAEERGTRLCASRRAGTATPAATPVPTVG
Sbjct: 241 SFRLLQEALEAEERGTRLCASRRAGTATPAATPVPTVG 278
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 497 bits (1279), Expect = e-141
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
Query: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS
Sbjct: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
Query: 241 SFRLLQEALEAEERG 255
SFRLLQEALEAEERG
Sbjct: 241 SFRLLQEALEAEERG 255
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 497 bits (1279), Expect = e-141
Identities = 255/255 (100%), Positives = 255/255 (100%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM
Sbjct: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS
Sbjct: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
Query: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
Query: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS
Sbjct: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
Query: 241 SFRLLQEALEAEERG 255
SFRLLQEALEAEERG
Sbjct: 241 SFRLLQEALEAEERG 255
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 120 bits (301), Expect = 1e-27
Identities = 87/256 (33%), Positives = 132/256 (51%), Gaps = 37/256 (14%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
+D+ GP PWGFR+ GG+DF P+ +++V KA A+L GD+I AI+GE+ M H E
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 65 AQSKIRQSPSPLRLQLDRSQ--ATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSY 122
AQ++I+ L L + RS+ SP T +G Y + +S
Sbjct: 66 AQNRIKGCTDNLTLTVARSEHKVWSPLVTE------------EGKRHPYKMNLASEPQEV 113
Query: 123 SSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLS-YSGRPGSRQA 181
S R+ PF+ P+SS T I+ + + A GL +++ +S ++ S+ A
Sbjct: 114 LHIGSAHNRSAMPFTASPASS--TTARVITNQYNNPA---GLYSSENISNFNNALESKTA 168
Query: 182 GLGRAGDSAVL--VLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQS 239
G +S L PPS SL++D++SEV+KMLQE +E P+QS
Sbjct: 169 ASGVEANSRPLDHAQPPS---------------SLVIDKESEVYKMLQEKQELNEPPKQS 213
Query: 240 SSFRLLQEALEAEERG 255
+SF +LQE LE+EE+G
Sbjct: 214 TSFLVLQEILESEEKG 229
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 113 bits (282), Expect = 2e-25
Identities = 89/273 (32%), Positives = 121/273 (44%), Gaps = 44/273 (16%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M +V + GP+PWGFR+ GGRDF P+ +++V KA A L PGD+I AINGES E M
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
H EAQ++I+ L L + R + S DS + ++ + + S S
Sbjct: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
Query: 121 SYSS-PTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
+ P P GSP+ PP + + EA + +L SP
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP-------------- 166
Query: 177 GSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAA- 235
PPS P P +D SEV++ML+E E AA
Sbjct: 167 ------------------PPSADPARGLP----RSRDCRVDLGSEVYRMLREPAEPVAAE 204
Query: 236 PRQSSSFRLLQEALEAEERGTRLCASRRAGTAT 268
P+QS SFR LQ LEA E G S R GT++
Sbjct: 205 PKQSGSFRYLQGMLEAGEGG---APSSRHGTSS 234
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 111 bits (278), Expect = 6e-25
Identities = 85/260 (32%), Positives = 115/260 (44%), Gaps = 41/260 (15%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M +V + GP+PWGFR+ GGRDF P+ +++V KA A L PGD+I AINGES E M
Sbjct: 1 MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
H EAQ++I+ L L + R + S DS + ++ + + S S
Sbjct: 61 THLEAQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQAHRIHIDPEIQDGSPTTSRRPS 120
Query: 121 SYSS-PTSLSPRAGSPFSPPPS---SSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
+ P P GSP+ PP + + EA + +L SP
Sbjct: 121 GTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSP-------------- 166
Query: 177 GSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAA- 235
PPS P P +D SEV++ML+E E AA
Sbjct: 167 ------------------PPSADPARGLP----RSRDCRVDLGSEVYRMLREPAEPVAAE 204
Query: 236 PRQSSSFRLLQEALEAEERG 255
P+QS SFR LQ LEA E G
Sbjct: 205 PKQSGSFRYLQGMLEAGEGG 224
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 98.6 bits (244), Expect = 5e-21
Identities = 80/271 (29%), Positives = 130/271 (47%), Gaps = 39/271 (14%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M TV + GPAPWGFR++GG DF+ P+++T++ KA A+L PGD+I+AI+G E M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQA--TSPGQTNGDSSLEVLATRFQGSVR--TYTESQS 116
HA+AQ +I+ + L L++DR + SP Q + D + + Y E +
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHLWSP-QVSEDGKAHPFKINLESEPQDGNYFEHKH 119
Query: 117 SLR----------SSYSSPTSLSPRAGSPFSPPPSSSSLT----GEAAISRSFQSLACSP 162
++R S S+P+ + GS S P S S+++ G+ ++ +P
Sbjct: 120 NIRPKPFVIPGRSSGCSTPSGID--CGSGRSTPSSVSTVSTICPGDLKVAAKL-----AP 172
Query: 163 GLPAADRLSYSGRPGSRQAGLG-------RAGDSAVLVLPPSPGPRSSRPSMDSEGGSLL 215
+P L PG + + D+ + L + SE +
Sbjct: 173 NIPLEMEL-----PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSE-PTAS 226
Query: 216 LDEDSEVFKMLQENREGRAAPRQSSSFRLLQ 246
+ +S+V++ML +NR PRQS SFR+LQ
Sbjct: 227 VPPESDVYRMLHDNRNEPTQPRQSGSFRVLQ 257
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 95.1 bits (235), Expect = 6e-20
Identities = 72/246 (29%), Positives = 111/246 (45%), Gaps = 37/246 (15%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M TV + GPAPWGFR++GG DF+ P+++T++ KA A+L PGD+I+AI+G E M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120
HA+AQ +I+ + L L++DR G++ L G + + S
Sbjct: 61 THADAQDRIKAAAHQLCLKIDR----------GETHLWSPQVSEDGKAHPFKINLESEPQ 110
Query: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180
+ + R PF A I Q ++ S P + +
Sbjct: 111 EFKPIGTAHNRRAQPF---------VAAANIDDKRQVVSASYNSP----IGLYSTSNIQD 157
Query: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240
A G+ ++ P P +S P +S+V++ML +NR PRQS
Sbjct: 158 ALHGQL--RGLIPSSPQNEPTASVP------------PESDVYRMLHDNRNEPTQPRQSG 203
Query: 241 SFRLLQ 246
SFR+LQ
Sbjct: 204 SFRVLQ 209
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 89.7 bits (221), Expect = 2e-18
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS 117
H EAQ+KI+ + L L L +S+ P T + L V+ + ++ T
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDT------- 113
Query: 118 LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSL--ACSPGLPAADRLSYS 173
S +P+ SP +P T A SR +F SL A PG P A + +
Sbjct: 114 -NGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 172
Query: 174 GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG 232
G+R +L P P SS+P + L E E+ +M Q + G
Sbjct: 173 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 220
Query: 233 RAA 235
+A+
Sbjct: 221 KAS 223
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 89.7 bits (221), Expect = 2e-18
Identities = 71/243 (29%), Positives = 113/243 (46%), Gaps = 28/243 (11%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNG---DSSLEVLATRFQGSVRTYTESQSS 117
H EAQ+KI+ + L L L +S+ P T + L V+ + ++ T
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDT------- 113
Query: 118 LRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISR--SFQSL--ACSPGLPAADRLSYS 173
S +P+ SP +P T A SR +F SL A PG P A + +
Sbjct: 114 -NGSLVAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKT 172
Query: 174 GRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDED-SEVFKMLQENREG 232
G+R +L P P SS+P + L E E+ +M Q + G
Sbjct: 173 SPEGARD------------LLGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRG 220
Query: 233 RAA 235
+A+
Sbjct: 221 KAS 223
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 89.7 bits (221), Expect = 2e-18
Identities = 63/193 (32%), Positives = 99/193 (51%), Gaps = 14/193 (7%)
Query: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
Query: 64 EAQSKIRQSPSPLRLQLDRSQAT---SPGQTNGDSSLEVL----ATRFQGSVRTYTESQS 116
EAQ+KI+ L + L R+ A P EV+ T S T T + +
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMA 124
Query: 117 SLRS-----SYSSPTSLS-PRAGSPFSPP-PSSSSLTGEAAISRSFQSLACSPGLPAADR 169
++ S SSP S P S F+P ++SS + ++ L + GL A
Sbjct: 125 YNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHANAN 184
Query: 170 LSYSGRPGSRQAG 182
LS P + AG
Sbjct: 185 LSADQSPSALSAG 197
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 85.9 bits (211), Expect = 4e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
Query: 64 EAQSKIRQSPSPLRLQLDRSQA 85
EAQ+KI+ L + L R+ A
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASA 86
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 85.9 bits (211), Expect = 4e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
Query: 64 EAQSKIRQSPSPLRLQLDRSQA 85
EAQ+KI+ L + L R+ A
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASA 86
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 85.9 bits (211), Expect = 4e-17
Identities = 36/82 (43%), Positives = 59/82 (71%)
Query: 4 TVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHA 63
+V + GPAPWGFR+ GG+DF+ P+ ++ + + GKA A++R GD++++I+G +A+GM H
Sbjct: 5 SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64
Query: 64 EAQSKIRQSPSPLRLQLDRSQA 85
EAQ+KI+ L + L R+ A
Sbjct: 65 EAQNKIKGCTGSLNMTLQRASA 86
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 81.3 bits (199), Expect = 9e-16
Identities = 36/91 (39%), Positives = 58/91 (63%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQT 91
H EAQ+KI+ + L L L +S+ P T
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPIST 91
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 81.3 bits (199), Expect = 9e-16
Identities = 36/91 (39%), Positives = 58/91 (63%)
Query: 1 MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60
M+ +V + GP PWGFR+ GG+DF+ P+ ++++ KA + L GD++VAI+G + + M
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 LHAEAQSKIRQSPSPLRLQLDRSQATSPGQT 91
H EAQ+KI+ + L L L +S+ P T
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPIST 91
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 78.6 bits (192), Expect = 6e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQSKIRQSPSPLRLQLDRSQ 84
AQ+KIR L L L R+Q
Sbjct: 66 AQNKIRACGERLSLGLSRAQ 85
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 78.6 bits (192), Expect = 6e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQSKIRQSPSPLRLQLDRSQ 84
AQ+KIR L L L R+Q
Sbjct: 66 AQNKIRACGERLSLGLSRAQ 85
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 78.6 bits (192), Expect = 6e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
Query: 65 AQSKIRQSPSPLRLQLDRSQ 84
AQ+KIR L L L R+Q
Sbjct: 66 AQNKIRACGERLSLGLSRAQ 85
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 68.6 bits (166), Expect = 6e-12
Identities = 38/97 (39%), Positives = 54/97 (55%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
V ++G APWGFR+ GG + P+ V+K+ R +A A LR D ++AING S + HA
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 65 AQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLA 101
A S I S + L L + R P Q+ L+VL+
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLS 105
Score = 30.8 bits (68), Expect = 1.4
Identities = 38/152 (25%), Positives = 54/152 (35%), Gaps = 13/152 (8%)
Query: 66 QSKIRQSPSPLRLQLDRSQATSPGQTNGDS-------SLEVLATRFQGSV--RTYTESQS 116
+ + + SP+P L L ++ P +S SL A F V R+Y
Sbjct: 641 KEETKNSPNPELLSLVQNLDEKPRAGGAESGPEEDALSLGAEACNFMQPVGARSYKTLPH 700
Query: 117 SLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRP 176
+ +P +P +PPP + + A S G+P RL GR
Sbjct: 701 VTPKTPPPMAPKTPPPMTPKTPPPVAPKPPSRGLLDGLVNGAASSAGIPEPPRL--QGRG 758
Query: 177 GSRQAGLGRAGDSAVLVLPPSP--GPRSSRPS 206
G A D V+ P P GPR PS
Sbjct: 759 GELFAKRQSRADRYVVEGTPGPGLGPRPRSPS 790
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 60.1 bits (144), Expect = 2e-09
Identities = 56/183 (30%), Positives = 83/183 (45%), Gaps = 22/183 (12%)
Query: 7 VAGPAPWGFRITGGRDF--HTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
V G A +G + GGRD TP+ V + + G A+ L GD+++ INGES +G+ HA
Sbjct: 62 VRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHA 121
Query: 64 EAQSKIRQSPSPLRLQLDRSQATSPGQTNG--------DSSLEVLATRFQGSVRTYTESQ 115
+A +IR L L + R T PG+ G D S + GS S
Sbjct: 122 QAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVDRSPDPGGPEVTGS----RSSS 177
Query: 116 SSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQ----SLACSPG---LPAAD 168
+SL S T+L GSP P +++ + R + + SPG +P+ +
Sbjct: 178 TSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWLVPSEE 237
Query: 169 RLS 171
RLS
Sbjct: 238 RLS 240
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 58.2 bits (139), Expect = 8e-09
Identities = 56/188 (29%), Positives = 83/188 (44%), Gaps = 27/188 (14%)
Query: 7 VAGPAPWGFRITGGRDF--HTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
V G A +G + GGRD TP+ V + + G A+ L GD+++ INGES +G+ HA
Sbjct: 129 VRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTHA 188
Query: 64 EAQSKIRQSPSPLRLQLDRSQATSPGQTNG-------------DSSLEVLATRFQGSVRT 110
+A +IR L L + R T PG+ G D S + GS
Sbjct: 189 QAVERIRAGGPQLHLVIRRPLETHPGKPRGVGEPRKGVVPSWPDRSPDPGGPEVTGS--- 245
Query: 111 YTESQSSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQ----SLACSPG--- 163
S +SL S T+L GSP P +++ + R + + SPG
Sbjct: 246 -RSSSTSLVQHPPSRTTLKKTRGSPEPSPEAAADGPTVSPPERRAEDPNDQIPGSPGPWL 304
Query: 164 LPAADRLS 171
+P+ +RLS
Sbjct: 305 VPSEERLS 312
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 56.6 bits (135), Expect = 2e-08
Identities = 81/316 (25%), Positives = 117/316 (37%), Gaps = 85/316 (26%)
Query: 4 TVDVA-GPAPWGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGML 61
TVD+ G +GF I GGR++ + V ++AE G A ++ +R GD I+ INGES M
Sbjct: 1147 TVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMT 1206
Query: 62 HAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSS 121
HA A I+ +RL L R G V Y E +
Sbjct: 1207 HARAIELIKSGGRRVRLLLKRG---------------------TGQVPEYDEP-----AP 1240
Query: 122 YSSPTSLSPRAG----------SPFSP----PPSSSS----------LTGEAAISRSFQS 157
+SSP + +P +PFSP PPS S + E + + +
Sbjct: 1241 WSSPAAAAPGLPEVGVSLDDGLAPFSPSHPAPPSDPSHQISPGPTWDIKREHDVRKPKEL 1300
Query: 158 LACSPGLPAADRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPG-PRSSRPSMDSEGGSLLL 216
AC + G R A RA + P G P + RP+ ++ L
Sbjct: 1301 SAC------GQKKQRLGEQRERSASPQRAARPRLEEAPGGQGRPEAGRPASEARAPGLAA 1354
Query: 217 DEDSEVFKMLQENREGRAAPRQSSSFRLLQE------------------ALEAEER-GTR 257
+ ++ + G+ APR ++ L + ALEAE R G R
Sbjct: 1355 ADAADAAR-----AGGKEAPRAAAGSELCRREGPGAAPAFAGPGGGGSGALEAEGRAGAR 1409
Query: 258 LCASRRAGTATPAATP 273
A R G P P
Sbjct: 1410 --AGPRPGPRPPGGAP 1423
Score = 43.9 bits (102), Expect = 2e-04
Identities = 43/147 (29%), Positives = 66/147 (44%), Gaps = 15/147 (10%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GFRI GG + PI++ V G A +D L PGD +V ++G G H +
Sbjct: 788 FGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHH 847
Query: 72 SPSPLRLQLD-RSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSP 130
+ ++ L R + G+ ++ R GSV T+ SS RS Y++ T+ +
Sbjct: 848 AARNGQVNLTVRRKVLCGGEPCPENG------RSPGSVSTH---HSSPRSDYATYTNSNH 898
Query: 131 RAGSPFSPPP----SSSSLTGEAAISR 153
A S + PP S S T + I R
Sbjct: 899 AAPSSNASPPEGFASHSLQTSDVVIHR 925
Score = 32.3 bits (72), Expect = 0.47
Identities = 31/141 (21%), Positives = 56/141 (39%), Gaps = 12/141 (8%)
Query: 16 RITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQSPS 74
R G P + ++ + A + A L+ GD I+A+NG+S M HA+ I+ +
Sbjct: 941 RPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGL 1000
Query: 75 PLRLQ-LDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAG 133
+ L+ + + + SP +A +S + +S + P+ +P +
Sbjct: 1001 SVTLRIIPQEELNSPTSAPSSEKQSPMA----------QQSPLAQQSPLAQPSPATPNSP 1050
Query: 134 SPFSPPPSSSSLTGEAAISRS 154
PP L G RS
Sbjct: 1051 IAQPAPPQPLQLQGHENSYRS 1071
Score = 30.8 bits (68), Expect = 1.4
Identities = 20/62 (32%), Positives = 28/62 (45%), Gaps = 1/62 (1%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GF I GG + + V V G A +D + GD+IV IN G HA+ +
Sbjct: 436 FGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQS 495
Query: 72 SP 73
P
Sbjct: 496 VP 497
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 54.7 bits (130), Expect = 9e-08
Identities = 34/90 (37%), Positives = 48/90 (53%), Gaps = 3/90 (3%)
Query: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKAK--DADLRPGDIIVAINGESAEGMLHAEAQ 66
G APWGF + GG + P++++KV E GKA + L+ GD +V IN E EA
Sbjct: 34 GGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQAGDEVVHIN-EVTLSSSRKEAV 92
Query: 67 SKIRQSPSPLRLQLDRSQATSPGQTNGDSS 96
S ++ S LRL + R T PG + +S
Sbjct: 93 SLVKGSYKTLRLVVRRDVCTDPGHADTGAS 122
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/80 (30%), Positives = 42/80 (52%)
Query: 3 LTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLH 62
+ + + G APWGFR+ GG++ P+ V K+ + KA + L GD +V+ING + +
Sbjct: 7 ICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTY 66
Query: 63 AEAQSKIRQSPSPLRLQLDR 82
E + L++ + R
Sbjct: 67 PEVIKLMESITDSLQMLIKR 86
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/80 (30%), Positives = 42/80 (52%)
Query: 3 LTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLH 62
+ + + G APWGFR+ GG++ P+ V K+ + KA + L GD +V+ING + +
Sbjct: 7 ICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTY 66
Query: 63 AEAQSKIRQSPSPLRLQLDR 82
E + L++ + R
Sbjct: 67 PEVIKLMESITDSLQMLIKR 86
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 54.3 bits (129), Expect = 1e-07
Identities = 24/80 (30%), Positives = 42/80 (52%)
Query: 3 LTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLH 62
+ + + G APWGFR+ GG++ P+ V K+ + KA + L GD +V+ING + +
Sbjct: 7 ICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTY 66
Query: 63 AEAQSKIRQSPSPLRLQLDR 82
E + L++ + R
Sbjct: 67 PEVIKLMESITDSLQMLIKR 86
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 53.9 bits (128), Expect = 2e-07
Identities = 75/273 (27%), Positives = 109/273 (39%), Gaps = 41/273 (15%)
Query: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHAEAQS 67
G +GF + GGR+++ + V ++AE G A+ +R GD I+ INGE+ + M H+ A
Sbjct: 1129 GAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTKNMKHSRAIE 1188
Query: 68 KIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQG--SVRTYTESQS--SLRSSY- 122
I+ +RL L R + P + + S AT QG VR + + SL SSY
Sbjct: 1189 LIKNGGRRVRLFLKRGDGSVP-EYDPSSDRHGPATGPQGVPEVRAGPDRRQHPSLESSYP 1247
Query: 123 -----SSP------TSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLS 171
SSP + P+ +S P+ SR S AC P A +
Sbjct: 1248 PDLHKSSPHGEKRAHARDPKGSREYSRQPNEHHTWN--GTSRKPDSGACRPKDRAPE--- 1302
Query: 172 YSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQ---- 227
G R A RA A P P R S +L E E + +
Sbjct: 1303 -----GRRDAQAERA---AAANGPKRRSPEKRREGTRSADNTLERREKHEKRRDVSPERR 1354
Query: 228 ------ENREGRAAPRQSSSFRLLQEALEAEER 254
R+G + R+ S RLL++ E R
Sbjct: 1355 RERSPTRRRDGSPSRRRRSLERLLEQRRSPERR 1387
Score = 37.0 bits (84), Expect = 0.019
Identities = 29/125 (23%), Positives = 54/125 (43%), Gaps = 3/125 (2%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GFRI GG + PI + + G A D LR GD ++ ++G G H ++Q
Sbjct: 823 FGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVVQLMQQ 882
Query: 72 SPSP--LRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLS 129
+ + L + R + +T + + + TE + + + S +S ++S
Sbjct: 883 AAKQGHVNLTVRRKVVFAVPKTENEVPSPASSHHSSNQPASLTEEKRTPQGSQNSLNTVS 942
Query: 130 PRAGS 134
+GS
Sbjct: 943 SGSGS 947
Score = 30.8 bits (68), Expect = 1.4
Identities = 19/79 (24%), Positives = 40/79 (50%), Gaps = 6/79 (7%)
Query: 43 LRPGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLAT 102
L+ GD I+A+NG S H++ + I+++ + + L++ PG + +++L A
Sbjct: 1024 LKVGDRILAVNGCSITNKSHSDIVNLIKEAGNTVTLRI------IPGDESSNATLLTNAE 1077
Query: 103 RFQGSVRTYTESQSSLRSS 121
+ T+T SQ + +
Sbjct: 1078 KIATITTTHTPSQQGTQET 1096
Score = 29.6 bits (65), Expect = 3.0
Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 1/70 (1%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKAK-DADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GF + GG + + + + G A D + GD+IV++N G HA+ +
Sbjct: 482 FGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVNDTCVLGHTHAQVVKIFQS 541
Query: 72 SPSPLRLQLD 81
P + L+
Sbjct: 542 IPIGASVDLE 551
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 52.0 bits (123), Expect = 6e-07
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
V ++G APWGF + GGR+ P+++TK+ E KA D L GD IV IN G
Sbjct: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSG-FRQ 87
Query: 64 EAQSKIRQSPSPLRLQLDR 82
EA ++ S L+L + R
Sbjct: 88 EAICLVKGSHKTLKLVVKR 106
Score = 29.6 bits (65), Expect = 3.0
Identities = 48/172 (27%), Positives = 63/172 (36%), Gaps = 15/172 (8%)
Query: 64 EAQSKIRQSPSPLRLQLDRSQATSPGQT--NGDSSLEVLATRF------QGSVRTYTESQ 115
E QS RQ+ + R SQ P Q N + E+ R +G R T +
Sbjct: 958 EGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPR 1017
Query: 116 SSLRSSYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGR 175
S S+P L PRA SP SP + +S + S +P P +
Sbjct: 1018 DYRYSEESTPADLGPRAQSPGSPLHARGQ--DSWPVSSALLSKRPAPQRPPPPK----RE 1071
Query: 176 PGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQ 227
P +A G D+ V VL P P S S+D L L VF Q
Sbjct: 1072 PRRYRATDGAPADAPVGVL-GRPFPTPSPASLDVYVARLSLSHSPSVFSSAQ 1122
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 50.4 bits (119), Expect = 2e-06
Identities = 28/87 (32%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Query: 9 GPAPWGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQS 67
GP +GF + GG++++ + + ++AE G A KD + GD IV INGE +G+ H A
Sbjct: 1027 GPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGITHTRAIE 1086
Query: 68 KIRQSPSPLRLQLDRSQATSPGQTNGD 94
I+ + + L L P + D
Sbjct: 1087 LIQAGGNKVLLLLRPGTGLIPDHGDWD 1113
Score = 37.4 bits (85), Expect = 0.015
Identities = 33/150 (22%), Positives = 60/150 (40%), Gaps = 1/150 (0%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GF I GG + V V + G A +D + PGD+IV ING G HA+ +
Sbjct: 420 FGFTIIGGDRPDEFLQVKNVLKDGPAAQDGKIAPGDVIVDINGNCVLGHTHADVVQMFQL 479
Query: 72 SPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPR 131
P + L + + D ++++A + ++ T+ ++ + P ++
Sbjct: 480 VPVNQYVNLTLCRGYPLPDDSEDPVVDIVAATPVINGQSLTKGETCMNPQDFKPGAMVLE 539
Query: 132 AGSPFSPPPSSSSLTGEAAISRSFQSLACS 161
+ L G + S S+A S
Sbjct: 540 QNGKSGHTLTGDGLNGPSDASEQRVSMASS 569
Score = 32.7 bits (73), Expect = 0.36
Identities = 18/65 (27%), Positives = 32/65 (49%), Gaps = 6/65 (9%)
Query: 45 PGDIIVAINGESAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRF 104
PGD+++ +NG G+ + + + IR P+RL + PG+ L+ +F
Sbjct: 67 PGDVLLEVNGTPVSGLTNRDTLAVIRHFREPIRL-----KTVKPGKVINKDLRHYLSLQF 121
Query: 105 Q-GSV 108
Q GS+
Sbjct: 122 QKGSI 126
Score = 30.0 bits (66), Expect = 2.3
Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 19/129 (14%)
Query: 13 WGFRITGGRDFHTPIMVTKVAERGKA-KDADLRPGDIIVAINGESAEGMLHAEAQSKIRQ 71
+GFR+ GG I + + G A KD LR D ++ I+G +G H +
Sbjct: 736 FGFRVLGGDGPDQSIYIGAIIPLGAAEKDGRLRAADELMCIDGIPVKGKSHKQV------ 789
Query: 72 SPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRSSYSSPTSLSPR 131
L L + A NG L V F G + +S + S+ + L+ R
Sbjct: 790 ------LDLMTTAA-----RNGHVLLTVRRKIFYGEKQPEDDSSQAFISTQNGSPRLN-R 837
Query: 132 AGSPFSPPP 140
A P P P
Sbjct: 838 AEVPARPAP 846
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,098,027
Number of Sequences: 37866
Number of extensions: 625667
Number of successful extensions: 4015
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 347
Number of HSP's that attempted gapping in prelim test: 3408
Number of HSP's gapped (non-prelim): 888
length of query: 278
length of database: 18,247,518
effective HSP length: 101
effective length of query: 177
effective length of database: 14,423,052
effective search space: 2552880204
effective search space used: 2552880204
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.