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Search of human proteins with 33598937
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33598937 scavenger receptor class F, member 2 isoform 2
[Homo sapiens]
(865 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 1900 0.0
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 1894 0.0
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 608 e-174
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 556 e-158
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 431 e-120
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 291 1e-78
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 290 5e-78
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 288 2e-77
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 275 2e-73
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 158 2e-38
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 140 7e-33
gi|21264602 laminin alpha 5 [Homo sapiens] 140 7e-33
gi|153946395 tenascin C precursor [Homo sapiens] 137 3e-32
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 130 7e-30
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 129 9e-30
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 129 9e-30
gi|143770880 laminin, beta 4 [Homo sapiens] 129 1e-29
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 127 4e-29
gi|219842266 usherin isoform B [Homo sapiens] 126 1e-28
gi|219842259 usherin isoform A [Homo sapiens] 126 1e-28
gi|148833508 notch1 preproprotein [Homo sapiens] 124 3e-28
gi|4557679 jagged 1 precursor [Homo sapiens] 124 4e-28
gi|134244285 Notch homolog 3 [Homo sapiens] 119 9e-27
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 119 2e-26
gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens] 117 4e-26
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 116 1e-25
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 114 4e-25
gi|55770876 notch4 preproprotein [Homo sapiens] 113 7e-25
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 112 1e-24
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 112 1e-24
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 1900 bits (4922), Expect = 0.0
Identities = 865/865 (100%), Positives = 865/865 (100%)
Query: 1 MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ 60
MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ
Sbjct: 1 MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ 60
Query: 61 VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP
Sbjct: 61 VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
Query: 121 DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ 180
DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ
Sbjct: 121 DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ 180
Query: 181 CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240
CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC
Sbjct: 181 CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240
Query: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG
Sbjct: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
Query: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE 360
RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE
Sbjct: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE 360
Query: 361 TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS 420
TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS
Sbjct: 361 TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS 420
Query: 421 CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLG 480
CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLG
Sbjct: 421 CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLG 480
Query: 481 RKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPS 540
RKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPS
Sbjct: 481 RKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPS 540
Query: 541 WSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAI 600
WSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAI
Sbjct: 541 WSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPASAEEAI 600
Query: 601 PLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPA 660
PLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPA
Sbjct: 601 PLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPA 660
Query: 661 TKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPT 720
TKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPT
Sbjct: 661 TKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPT 720
Query: 721 PRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSL 780
PRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSL
Sbjct: 721 PRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSL 780
Query: 781 GRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKT 840
GRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKT
Sbjct: 781 GRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKT 840
Query: 841 PIQKPPRKKSREAAGELGRAGAPTL 865
PIQKPPRKKSREAAGELGRAGAPTL
Sbjct: 841 PIQKPPRKKSREAAGELGRAGAPTL 865
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 1894 bits (4906), Expect = 0.0
Identities = 865/870 (99%), Positives = 865/870 (99%), Gaps = 5/870 (0%)
Query: 1 MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ 60
MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ
Sbjct: 1 MEGAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQ 60
Query: 61 VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP
Sbjct: 61 VPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP 120
Query: 121 DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ 180
DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ
Sbjct: 121 DCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQ 180
Query: 181 CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240
CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC
Sbjct: 181 CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240
Query: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG
Sbjct: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
Query: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE 360
RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE
Sbjct: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCE 360
Query: 361 TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS 420
TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS
Sbjct: 361 TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS 420
Query: 421 CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPT-----RR 475
CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPT RR
Sbjct: 421 CHEDTCDPVTGACHLETNQRKGVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRPRPRR 480
Query: 476 ELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLE 535
ELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLE
Sbjct: 481 ELSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLE 540
Query: 536 QPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPAS 595
QPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPAS
Sbjct: 541 QPSPSWSSRASFSSFDTTDEGPVYCVPHEEAPAESRDPEVPTVPAEAPAPSPVPLTTPAS 600
Query: 596 AEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPP 655
AEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPP
Sbjct: 601 AEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPP 660
Query: 656 PPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPR 715
PPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPR
Sbjct: 661 PPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPR 720
Query: 716 TRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRG 775
TRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRG
Sbjct: 721 TRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRG 780
Query: 776 KTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPET 835
KTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPET
Sbjct: 781 KTRSLGRAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPET 840
Query: 836 PRKKTPIQKPPRKKSREAAGELGRAGAPTL 865
PRKKTPIQKPPRKKSREAAGELGRAGAPTL
Sbjct: 841 PRKKTPIQKPPRKKSREAAGELGRAGAPTL 870
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 608 bits (1568), Expect = e-174
Identities = 333/856 (38%), Positives = 430/856 (50%), Gaps = 70/856 (8%)
Query: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85
LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG
Sbjct: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAEL-QCCAGWRQKDQECTIPICEGPDA 62
Query: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A
Sbjct: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122
Query: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYC-SATSRCDPQTGACLCH 203
RWGARCE C C HG C P +G C CEPGWW + C C C +A +RC+ TGAC+C
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182
Query: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263
GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG
Sbjct: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
Query: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
+RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G +
Sbjct: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
Query: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
GE C +CP CR G AC TG C RC+ GW+G RCE C GT+GEDC C C G
Sbjct: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362
Query: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGV 443
CD +G C+CS G GP CN +CP G HG +C+ C C E C PV+G+C + R
Sbjct: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTA 422
Query: 444 MGAGALLVLLVCLL-LSLLGCCCACRGKD----PTRRELSLGRKKAPHRLCGRFSRISMK 498
+ AG+L+ LL+ L L+ CCC D P R ++ R K ++ G + +
Sbjct: 423 LIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKL--QVWGTLTSLGST 480
Query: 499 LPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSS---FDTTDE 555
LP L KLP V V+HHD + N SF+EPPS W++ SFSS DE
Sbjct: 481 LPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSA------GWATDDSFSSDPESGEADE 534
Query: 556 GPVYCVPHEE-----APAESRD----------PEVPTVPAEAPAPSPVPLTTPASAEEAI 600
P YCVP +E A A S + PE + P P S + S A
Sbjct: 535 VPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPRTSSLARAKRPSVSFAE 594
Query: 601 PLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPA 660
+ S RS+ + P R +R +R A++ E S PE + P PA
Sbjct: 595 GTKFAPQSRRSSGELSSP-----LRKPKRLSRGAQSGPEGREAEESTGPEEAEAPESFPA 649
Query: 661 TKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPT 720
G GR + E + S T A G PR +
Sbjct: 650 AASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYMLA-----GKPRGSEGP 704
Query: 721 PR---------PPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAA 771
R G E A P PPR +A R G+ G S + S A
Sbjct: 705 VRSVFRHFGSFQKGQAEAKVKRAIPKPPR---QALNRKKGSPG-LASGSVGQSPNSAPKA 760
Query: 772 DVRGKTRSLG-RAEVALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGPEKAATDL 830
+ G T + R E A+ G A + ++R+ P S +P E+ +
Sbjct: 761 GLPGATGPMAVRPEEAVRGLG-----AGTESSRRAQEPVSGCGSPEQDPQKQAEEERQEE 815
Query: 831 PAPETPRKKTPIQKPP 846
P E PI +PP
Sbjct: 816 PEYE---NVVPISRPP 828
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 556 bits (1434), Expect = e-158
Identities = 241/497 (48%), Positives = 305/497 (61%), Gaps = 14/497 (2%)
Query: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85
LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG
Sbjct: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAEL-QCCAGWRQKDQECTIPICEGPDA 62
Query: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A
Sbjct: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122
Query: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYC-SATSRCDPQTGACLCH 203
RWGARCE C C HG C P +G C CEPGWW + C C C +A +RC+ TGAC+C
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182
Query: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263
GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG
Sbjct: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
Query: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
+RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G +
Sbjct: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
Query: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
GE C +CP CR G AC TG C RC+ GW+G RCE C GT+GEDC C C G
Sbjct: 303 GESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGS 362
Query: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKGV 443
CD +G C+CS G GP CN +CP G HG +C+ C C E C PV+G+C + R
Sbjct: 363 CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGLCHPVSGSCQPGSGSRDTA 422
Query: 444 MGAGALLVLLVCLL-LSLLGCCCACRGKD----PTRRELSLGRKKAPHRLCGRFSRISMK 498
+ AG+L+ LL+ L L+ CCC D P R ++ R K ++ G + +
Sbjct: 423 LIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRMKL--QVWGTLTSLGST 480
Query: 499 LPRIPLRRQKLPKVVVA 515
LP L KLP V +
Sbjct: 481 LPCRSLSSHKLPWVTAS 497
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 431 bits (1108), Expect = e-120
Identities = 176/328 (53%), Positives = 218/328 (66%), Gaps = 7/328 (2%)
Query: 28 LLLLLLLWMLPDTVAPQELNPRGRNVCRA--PGSQVPTCCAGWRQQGDECGIAVCEGNST 85
LL LLLLW EL+P+G++VC A P +++ CCAGWRQ+ EC I +CEG
Sbjct: 6 LLPLLLLWTRG--TQGSELDPKGQHVCVASSPSAELQ-CCAGWRQKDQECTIPICEGPDA 62
Query: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
C ++EVCV+PG CRC+ G+FGA+C ++CP Q+WGPDC+E C CHPHGQCE TG C C A
Sbjct: 63 CQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQA 122
Query: 146 RRWGARCEHACQC-QHGTCHPRSGACRCEPGWWGAQCASACYCS-ATSRCDPQTGACLCH 203
RWGARCE C C HG C P +G C CEPGWW + C C C+ A +RC+ TGAC+C
Sbjct: 123 DRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCK 182
Query: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG 263
GWWGR C+ +C C+ SPCEQ SGRC CR +G C + C+C RGRC G C C PG
Sbjct: 183 PGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGRCSAASGECTCPPG 242
Query: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
+RG C PCPAG +G+ C CG+CK +PC+ G C +CEPGWNGT+C QPC G +
Sbjct: 243 FRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTF 302
Query: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCN 351
GE C +CP CR G AC TG C RC+
Sbjct: 303 GESCEQQCPHCRHGEACEPDTGHCQRCS 330
Score = 256 bits (653), Expect = 8e-68
Identities = 225/752 (29%), Positives = 296/752 (39%), Gaps = 123/752 (16%)
Query: 152 CEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSC 211
CE CQ + G CRC+PG++GA C+S RC Q +WG C
Sbjct: 57 CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSS--------RCPGQ---------YWGPDC 99
Query: 212 NNQCACNS-SPCEQQSGRCQCRERTFGARCDRYCQCF-RGRCHPVDGTCACEPGYRGKYC 269
C C+ CE +G CQC+ +GARC+ C C GRC P G C CEPG+ C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 270 REPCPA------------------GFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNG 311
R PC G++G C RC C G PC GRC C PGW G
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN-CHGS-PCEQDSGRC-ACRPGWWG 216
Query: 312 TKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGED 371
+C Q C C G C+ +G+CT C G+ G RCE C G++G
Sbjct: 217 PECQQQCE--------------CVRGR-CSAASGECT-CPPGFRGARCELPCPAGSHGVQ 260
Query: 372 CAFVCADCGSGH-CDFQSGRC-LCSPGVHGPHCNVTCPPGLHGADCAQACS-C-HEDTCD 427
CA C C C +G C C PG +G C C PG G C Q C C H + C+
Sbjct: 261 CAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACE 320
Query: 428 PVTGACHLETNQRKGVMGAGALLVLLVCLL-LSLLGCCCACRGKD----PTRRELSLGRK 482
P TG C + R + AG+L+ LL+ L L+ CCC D P R ++ R
Sbjct: 321 PDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCACCCWAPRSDLKDRPARDGATVSRM 380
Query: 483 KAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWS 542
K ++ G + + LP L KLP V V+HHD + N SF+EPPS W+
Sbjct: 381 KL--QVWGTLTSLGSTLPCRSLSSHKLPWVTVSHHDPEVPFNHSFIEPPSA------GWA 432
Query: 543 SRASFSS---FDTTDEGPVYCVPHEE-----APAESRD----------PEVPTVPAEAPA 584
+ SFSS DE P YCVP +E A A S + PE + P P
Sbjct: 433 TDDSFSSDPESGEADEVPAYCVPPQEGMVPVAQAGSSEASLAAGAFPPPEDASTPFAIPR 492
Query: 585 PSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARARGEIGGLS 644
S + S A + S RS+ + P R +R +R A++ E
Sbjct: 493 TSSLARAKRPSVSFAEGTKFAPQSRRSSGELSSP-----LRKPKRLSRGAQSGPEGREAE 547
Query: 645 LSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDK 704
S PE + P PA G GR + E + S T
Sbjct: 548 ESTGPEEAEAPESFPAAASPGDSATGHRRPPLGGRTVAEHVEAIEGSVQESSGPVTTIYM 607
Query: 705 SAHTVEHGSPRTRDPTPR---------PPGLPEEATALAAPSPPRARARAAPRPLGAHGR 755
A G PR + R G E A P PPR +A R G+ G
Sbjct: 608 LA-----GKPRGSEGPVRSVFRHFGSFQKGQAEAKVKRAIPKPPR---QALNRKKGSPG- 658
Query: 756 RRSPAKRAEAASMLAADVRGKTRSLG-RAEVALGAQGPREKPAPPQKAKRSVPPASPARA 814
S + S A + G T + R E A+ G A + ++R+ P S +
Sbjct: 659 LASGSVGQSPNSAPKAGLPGATGPMAVRPEEAVRGLG-----AGTESSRRAQEPVSGCGS 713
Query: 815 PPATETPGPEKAATDLPAPETPRKKTPIQKPP 846
P E+ + P E PI +PP
Sbjct: 714 PEQDPQKQAEEERQEEPEYE---NVVPISRPP 742
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 291 bits (746), Expect = 1e-78
Identities = 160/433 (36%), Positives = 196/433 (45%), Gaps = 70/433 (16%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDC 122
C AGW C+ +C+ + C G C C G+ G +C C WGPDC
Sbjct: 817 CPAGWYGPS-------CQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC 869
Query: 123 KELCSCHP-HGQCEDVTGQCTCHARRWGARCEHAC-------------QCQHGT-CHPRS 167
C+C HG C+ ++G C C A G RCE C QCQHG C S
Sbjct: 870 SHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVS 929
Query: 168 GACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAG--------- 205
GAC C GW +G C SAC C+A + CD G+CLC AG
Sbjct: 930 GACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAET 989
Query: 206 ----WWGRSCNNQCAC-NSSPCEQQSGRCQCRER-------------TFGARCDRYCQCF 247
+G +C+ CAC N + C+ G+C C +G C C C
Sbjct: 990 CPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQ 1049
Query: 248 RG-RCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCE 306
G C PV G CAC G+ G C + C GCR G C C GRCL C
Sbjct: 1050 NGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHS-GGCLNGGLCDPHTGRCL-CP 1107
Query: 307 PGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNG 366
GW G KC PC G++GE C+ RC C G AC+HVTG C RC G+ G CE C G
Sbjct: 1108 AGWTGDKCQSPCLRGWFGEACAQRCS-CPPGAACHHVTGAC-RCPPGFTGSGCEQACPPG 1165
Query: 367 TYGEDCAFVCADCGSGH-CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HED 424
++GEDCA +C G C +G C C+ G HGP C CPPG +G C Q C C +
Sbjct: 1166 SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
Query: 425 TCDPVTGACHLET 437
+CD TGAC T
Sbjct: 1226 SCDAATGACRCPT 1238
Score = 280 bits (716), Expect = 4e-75
Identities = 139/389 (35%), Positives = 177/389 (45%), Gaps = 59/389 (15%)
Query: 86 CSENEVCVRP---------GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
CSE CV+P G C C+ G+ G C +C ++GP C + C+C C+
Sbjct: 650 CSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDS 709
Query: 137 VTGQC---------------TCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQC 181
V+G+C C +G C +C C CH +G CRC PG G C
Sbjct: 710 VSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC 769
Query: 182 ASAC--------------YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSG 227
+ C C +RCDP+TGACLC G+ G C + C
Sbjct: 770 EADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAG--------- 820
Query: 228 RCQCRERTFGARCDRYCQCFR-GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRC 286
+G C C C G CHP G C+C PG+ G C+ C G +G C C
Sbjct: 821 -------WYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPC 873
Query: 287 GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGK 346
G C G CL CE G+ G +C+Q C G +G GC RC C+ G AC+HV+G
Sbjct: 874 NCSAGHGSCDAISGLCL-CEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAACDHVSGA 931
Query: 347 CTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTC 406
CT C AGW G CE C G +G DC C CD +G CLC G GP C TC
Sbjct: 932 CT-CPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETC 990
Query: 407 PPGLHGADCAQACSCHED-TCDPVTGACH 434
P +G +C+QAC+C +CDPV G CH
Sbjct: 991 PAHTYGHNCSQACACFNGASCDPVHGQCH 1019
Score = 271 bits (694), Expect = 1e-72
Identities = 157/479 (32%), Positives = 190/479 (39%), Gaps = 113/479 (23%)
Query: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKC 113
TC AGWR G C A C C+ C G C C G G C C
Sbjct: 933 TCPAGWR--GTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETC 990
Query: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQC-------------TCHARRWGARCEHACQCQH 160
P +G +C + C+C C+ V GQC C A +G C H+C CQ+
Sbjct: 991 PAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQN 1050
Query: 161 G-TCHPRSGACRCEPGWWGAQCASACY-------------CSATSRCDPQTGACLCHAGW 206
G TC P SG C C GW G C C C CDP TG CLC AGW
Sbjct: 1051 GGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGW 1110
Query: 207 WGRSCNNQCA-----------CNSSP---CEQQSGRCQCRER-------------TFGAR 239
G C + C C+ P C +G C+C +FG
Sbjct: 1111 TGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGED 1170
Query: 240 CDRYCQC--FRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTV 297
C + CQC CHP GTC+C GY G C++ CP G YG GC + CG C C
Sbjct: 1171 CAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG-CLNGGSCDA 1229
Query: 298 AEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH-----------------RCPP------- 333
A G C C G+ GT C+ C G +G C+H CPP
Sbjct: 1230 ATGAC-RCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRC 1288
Query: 334 ------------------CRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFV 375
CR+G C+ G C+ C GW G CE C G YG C
Sbjct: 1289 ERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCS-CGLGWTGRHCELACPPGRYGAACHLE 1347
Query: 376 CADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
C+ + C+ +G C C PG +G C CPPG HGA C C C H CDP++G C
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRC 1406
Score = 268 bits (684), Expect = 2e-71
Identities = 148/425 (34%), Positives = 181/425 (42%), Gaps = 72/425 (16%)
Query: 72 GDECGIAV--CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCH 129
G +C + C TC + C C G+ G C+ CP +G +C CSC
Sbjct: 517 GHDCSLTCDDCRNGGTC-----LLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQ 571
Query: 130 PHGQCEDVTGQCTCHARRWGARCEHACQ--------------CQHGTCHPRSGACRCEPG 175
G C+ VTG C C G CE C G CH GAC C+PG
Sbjct: 572 NGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPG 631
Query: 176 ------------W-WGAQCASACYCSA--TSRCDPQTGACLCHAGWWGRSCNNQC----- 215
W +G C+ C C T CD + G+C C AG+ G C +C
Sbjct: 632 LYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYF 691
Query: 216 ------ACNSS---PCEQQSGRC---------------QCRERTFGARCDRYCQCFRGRC 251
AC C+ SG C +C TFG C C C C
Sbjct: 692 GPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPC 751
Query: 252 HPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNG 311
H V G C C PG G+ C CP G +GLGC+ C C+ C G CL C PG+ G
Sbjct: 752 HGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACL-CLPGFVG 810
Query: 312 TKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGED 371
++C C G+YG C RC DGH C+ TG C+ C GW G C+ C G +G D
Sbjct: 811 SRCQDVCPAGWYGPSCQTRCSCANDGH-CHPATGHCS-CAPGWTGFSCQRACDTGHWGPD 868
Query: 372 CAFVCADCGSGH--CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDP 428
C+ C +C +GH CD SG CLC G GP C CP G G C Q C C H CD
Sbjct: 869 CSHPC-NCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH 927
Query: 429 VTGAC 433
V+GAC
Sbjct: 928 VSGAC 932
Score = 261 bits (666), Expect = 3e-69
Identities = 143/415 (34%), Positives = 181/415 (43%), Gaps = 62/415 (14%)
Query: 78 AVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
A C + C +C G C C G+ G C + C R ++G C + CSC P C
Sbjct: 1083 AGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHH 1142
Query: 137 VTGQCTCHARRWGARCEHAC-------------QC--QHGTCHPRSGAC----------- 170
VTG C C G+ CE AC QC ++ CHP +G C
Sbjct: 1143 VTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSC 1202
Query: 171 --RCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN-------------NQC 215
RC PG +G C C C CD TGAC C G+ G CN + C
Sbjct: 1203 QQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVC 1262
Query: 216 ACNS-SPCEQQSGRCQCRERTFGARCDRYCQCFR--------------GRCHPVDGTCAC 260
C + C+ +G C C G RC+R C R G CH +G+C+C
Sbjct: 1263 GCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSC 1322
Query: 261 EPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCAT 320
G+ G++C CP G YG C C C C A G C C PG+ G C+ PC
Sbjct: 1323 GLGWTGRHCELACPPGRYGAACHLECS-CHNNSTCEPATGTC-RCGPGFYGQACEHPCPP 1380
Query: 321 GFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCG 380
GF+G GC C C+ G C+ ++G+C C AG+ G CE C G++GE C C G
Sbjct: 1381 GFHGAGCQGLCW-CQHGAPCDPISGRCL-CPAGFHGHFCERGCEPGSFGEGCHQRCDCDG 1438
Query: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT-CDPVTGACH 434
CD +G CLC PG G CN+ C G G C C C CDPV+G CH
Sbjct: 1439 GAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSGQCH 1493
Score = 240 bits (613), Expect = 4e-63
Identities = 139/405 (34%), Positives = 173/405 (42%), Gaps = 73/405 (18%)
Query: 64 CCAGWRQQGDECGIA--------VCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCP 114
C AGW GD+C C +C C G CRC G+ G+ C+ CP
Sbjct: 1106 CPAGWT--GDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACP 1163
Query: 115 RQFWGPDCKELCSCHPHGQ-CEDVTGQCTCHAR-------------RWGARCEHACQCQH 160
+G DC ++C C C TG C+C A R+G CE C C +
Sbjct: 1164 PGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLN 1223
Query: 161 G-TCHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW 206
G +C +GACRC G+ +G C C C + CDP TG CLC G
Sbjct: 1224 GGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGR 1283
Query: 207 -------------WGRSCNNQCAC-NSSPCEQQSGRCQCR-------------ERTFGAR 239
+G C + C+C N C +G C C +GA
Sbjct: 1284 AGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAA 1343
Query: 240 CDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
C C C C P GTC C PG+ G+ C PCP GF+G GC+ C C+ PC
Sbjct: 1344 CHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCW-CQHGAPCDPI 1402
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
GRCL C G++G C++ C G +GEGC RC C G C+ VTG C C G G
Sbjct: 1403 SGRCL-CPAGFHGHFCERGCEPGSFGEGCHQRCD-CDGGAPCDPVTGLCL-CPPGRSGAT 1459
Query: 359 CETKCSNGTYGEDCAFVCADCGSG-HCDFQSGRCLCSPGVHGPHC 402
C C G +G C C DCG G CD SG+C C G GP C
Sbjct: 1460 CNLDCRRGQFGPSCTLHC-DCGGGADCDPVSGQCHCVDGYMGPTC 1503
Score = 220 bits (561), Expect = 4e-57
Identities = 132/421 (31%), Positives = 180/421 (42%), Gaps = 69/421 (16%)
Query: 71 QGDECGI----AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK--- 123
Q D+ G A G T +E VC+ FG +C C G C
Sbjct: 486 QDDDVGADEEEAELRGEHTLTEKFVCLDDS--------FGHDCSLTCDDCRNGGTCLLGL 537
Query: 124 ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG-TCHPRSGACRCEPG------- 175
+ C C P G + + TC +G C +C CQ+G TC +GACRC PG
Sbjct: 538 DGCDC-PEGWTGLICNE-TCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCE 595
Query: 176 ------WWGAQCASACYCSATSRCDPQTGACLCHAGWWGR-------------SCNNQCA 216
++G C C C+ RC GACLC G +GR C+ +C
Sbjct: 596 DGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQ 655
Query: 217 C---NSSPCEQQSGRCQCRERTFGARCDRYCQ-------CFRG-------RCHPVDGTCA 259
C ++ C+++ G C C+ G RC C+ C++ C V G C
Sbjct: 656 CVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECG 715
Query: 260 --CEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
C G++G+ C + CP G +G+ C C C G PC G+C C PG G C+
Sbjct: 716 KRCPAGFQGEDCGQECPVGTFGVNCSSSCS-CGGA-PCHGVTGQC-RCPPGRTGEDCEAD 772
Query: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
C G +G GC CP C+ C+ TG C C G++G RC+ C G YG C C+
Sbjct: 773 CPEGRWGLGCQEICPACQHAARCDPETGACL-CLPGFVGSRCQDVCPAGWYGPSCQTRCS 831
Query: 378 DCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCH--EDTCDPVTGACHL 435
GHC +G C C+PG G C C G G DC+ C+C +CD ++G C
Sbjct: 832 CANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLC 891
Query: 436 E 436
E
Sbjct: 892 E 892
Score = 144 bits (362), Expect = 5e-34
Identities = 93/332 (28%), Positives = 121/332 (36%), Gaps = 109/332 (32%)
Query: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRC 100
G N P + +C AG+ G C CE C C G CRC
Sbjct: 1179 GENPACHPATGTCSCAAGYH--GPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRC 1236
Query: 101 RHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCE------- 153
G+ G +C+ CP+ +GP+C +C C C+ VTG C C R G RCE
Sbjct: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNR 1296
Query: 154 ------HACQCQHG--------------------------------------------TC 163
H C C++G TC
Sbjct: 1297 FGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTC 1356
Query: 164 HPRSGACRCEPGWWG-------------AQCASACYCSATSRCDPQTGACLCHAGW---- 206
P +G CRC PG++G A C C+C + CDP +G CLC AG+
Sbjct: 1357 EPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHF 1416
Query: 207 ---------WGRSCNNQCACNS-SPCEQQSGRC-------------QCRERTFGARCDRY 243
+G C+ +C C+ +PC+ +G C CR FG C +
Sbjct: 1417 CERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLH 1476
Query: 244 CQCFRGR-CHPVDGTCACEPGYRGKYCREPCP 274
C C G C PV G C C GY G CRE P
Sbjct: 1477 CDCGGGADCDPVSGQCHCVDGYMGPTCREGGP 1508
Score = 142 bits (357), Expect = 2e-33
Identities = 127/505 (25%), Positives = 180/505 (35%), Gaps = 127/505 (25%)
Query: 57 PGSQVPTCCAGWRQQGDE---CGIAVCE-GNSTCSEN--EVCVRPGECRCRHGYF----G 106
PGS + C G+R D I C GN C + ++ + C+CR G+ G
Sbjct: 180 PGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDG 239
Query: 107 ANCDTKCPRQFWGPDCKELCS---------CHPHGQ-------CEDV------------- 137
+C + P C C CH Q CEDV
Sbjct: 240 RHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG 299
Query: 138 ------TGQCTCHARRW----GARCE-------HACQ-----CQHGTCHPRSGA-CRCEP 174
+ +C CHA G +C ++C+ C HG H +G C C
Sbjct: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
Query: 175 GWW----------GAQCASACYCSATSRCDPQTGACLCHAGWW----GRSCNN--QCACN 218
G+ CA + C +P C C+AG+ G C + +CA +
Sbjct: 360 GYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASS 419
Query: 219 SSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVD--------------------- 255
CE C +F C+ + R C P++
Sbjct: 420 RGGCEHH---CTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAV 476
Query: 256 --------------GTCACEPGYRGKYC---REPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
G E RG++ + C +G C C C+ C +
Sbjct: 477 LQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLG 536
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
C C GW G C++ C +G+ CS C C++G C+ VTG C RC G G
Sbjct: 537 LDGC-DCPEGWTGLICNETCPPDTFGKNCSFSCS-CQNGGTCDSVTGAC-RCPPGVSGTN 593
Query: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
CE C G YG+ C C G C G CLC PG++G C++TCPP G C++
Sbjct: 594 CEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEE 653
Query: 419 CSC---HEDTCDPVTGACHLETNQR 440
C C H +CD G+C + R
Sbjct: 654 CQCVQPHTQSCDKRDGSCSCKAGFR 678
Score = 75.1 bits (183), Expect = 3e-13
Identities = 107/413 (25%), Positives = 131/413 (31%), Gaps = 89/413 (21%)
Query: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCE-GNSTCSENEVCVRPGECRCRHGYFGANC 109
R V V CC GW QQ DE G E S C CV PG + H
Sbjct: 97 RQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCV-PGSAQPCH------- 148
Query: 110 DTKCPRQFWGPDCK-ELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSG 168
CP F GP C+ ++ C H C+H C P S
Sbjct: 149 ---CPPGFQGPRCQYDVDECRTH-----------------NGGCQHRC-----VNTPGSY 183
Query: 169 ACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGR 228
C C+PG+ + C A + C G C H ++C C Q+ GR
Sbjct: 184 LCECKPGF--RLHTDSRTCLAINSCALGNGGCQHHCVQL-TITRHRCQCRPGFQLQEDGR 240
Query: 229 CQCRERTFGAR---CDRYCQCFRGRCHPVDGTCACEPGYR----GKYCR--EPCPAGFYG 279
R R C CQ RG C C GY+ GK C + C AG
Sbjct: 241 HCVRRSPCANRNGSCMHRCQVVRGLAR-----CECHVGYQLAADGKACEDVDECAAGL-- 293
Query: 280 LGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ-------PCATGFYGEGCSHRCP 332
C C +G C G E G +G +C + C GCSH C
Sbjct: 294 AQCAHGCLNTQGSFKCVCHAG----YELGADGRQCYRIEMEIVNSCEAN--NGGCSHGCS 347
Query: 333 PCRDGHACNHVTG--------KCTRCNAGWIGDRCETKCSNGTYGEDCAF-----VCAD- 378
G C G C + C+ C+N G +C + AD
Sbjct: 348 HTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADG 407
Query: 379 CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT--CDPV 429
CG D C S G HC T G C HED C P+
Sbjct: 408 CGCEDVD----ECASSRGGCEHHC--TNLAGSFQCSCEAGYRLHEDRRGCSPL 454
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 290 bits (741), Expect = 5e-78
Identities = 147/429 (34%), Positives = 201/429 (46%), Gaps = 67/429 (15%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
CC G+ + GD C I +C C CV P C C G+ G +C + C WGP C
Sbjct: 88 CCPGYYESGDFC-IPLC--TEECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143
Query: 124 ELCSCHPHGQCEDVTGQCTCHA--RRW-----------GARCEHACQCQHG-TCHPRSGA 169
C C C +TG C C A R W G C+ CQC+HG +C PR+G
Sbjct: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE 203
Query: 170 CRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW---------- 206
C C PG+ GA C C C C TG C C GW
Sbjct: 204 CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP 263
Query: 207 ---WGRSCNNQCAC-NSSPCEQQSGRCQCRE-------------RTFGARCDRYCQCFR- 248
+G++C+ C C + C+ +G+C C +FG +C ++C C
Sbjct: 264 PGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNG 323
Query: 249 GRCHPVDGTCACEPGYRGKYCREP-CPAGFYGLGCRRRCGQCKGQQ--PCTVAEGRCLTC 305
G+C P G C CEPGY+G C+E CP G +G GC C C C G C TC
Sbjct: 324 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC-PCDADNTISCHPVTGAC-TC 381
Query: 306 EPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSN 365
+PGW+G C++ C G+YG+GC C C++G C+ +TG CT C G++G+ C C+
Sbjct: 382 QPGWSGHHCNESCPVGYYGDGCQLPC-TCQNGADCHSITGGCT-CAPGFMGEVCAVSCAA 439
Query: 366 GTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HED 424
GTYG +C+ +C+ G C G C C G G C + CP G G +C ++C+C +
Sbjct: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA 499
Query: 425 TCDPVTGAC 433
C P+ G+C
Sbjct: 500 ACSPIDGSC 508
Score = 288 bits (737), Expect = 2e-77
Identities = 154/418 (36%), Positives = 190/418 (45%), Gaps = 66/418 (15%)
Query: 78 AVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
A CE C C GEC C G+ GA C CP +G +C + C CH GQC+
Sbjct: 226 AHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDH 285
Query: 137 VTGQCTCHARRWGARCEHAC-------QC-QH------GTCHPRSGACRCEPGWWGAQCA 182
VTGQC C A G RC+ C QC QH G C P +GAC CEPG+ G +C
Sbjct: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQ 345
Query: 183 S--------------ACYCSA--TSRCDPQTGACLCHAGWWGRSCNNQCAC--------- 217
C C A T C P TGAC C GW G CN C
Sbjct: 346 ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQL 405
Query: 218 -----NSSPCEQQSGRC-------------QCRERTFGARCDRYCQCFR-GRCHPVDGTC 258
N + C +G C C T+G C C C G C PVDG+C
Sbjct: 406 PCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
Query: 259 ACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPC 318
C+ G++G C PCP+G +GL C C C C+ +G C +C PGW G C+ PC
Sbjct: 466 TCKEGWQGLDCTLPCPSGTWGLNCNESC-TCANGAACSPIDGSC-SCTPGWLGDTCELPC 523
Query: 319 ATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCAD 378
G +G CS C C C+ VTG C C AGW G RC++ C G +G +C+ C+
Sbjct: 524 PDGTFGLNCSEHC-DCSHADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGPNCSVSCSC 581
Query: 379 CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACS-CHEDT--CDPVTGAC 433
G C + G C C+PG GP C CPPG +G CAQ C C + C ++G C
Sbjct: 582 ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC 639
Score = 285 bits (728), Expect = 2e-76
Identities = 147/437 (33%), Positives = 184/437 (42%), Gaps = 69/437 (15%)
Query: 63 TCCAGWRQQ--GDECGIAV----CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPR 115
TC GW + C + C+ TC C G C C G+ G C C
Sbjct: 380 TCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAA 439
Query: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCH-------------ARRWGARCEHACQCQHGT 162
+GP+C +CSC+ G C V G CTC + WG C +C C +G
Sbjct: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA 499
Query: 163 -CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW-- 206
C P G+C C PGW +G C+ C CS CDP TG C C AGW
Sbjct: 500 ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTG 559
Query: 207 -----------WGRSCNNQCAC-NSSPCEQQSGRCQCRERTFGARCDRYCQC-FRGR--- 250
WG +C+ C+C N C + G C+C G C R C F G
Sbjct: 560 IRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCA 619
Query: 251 ------------CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
CH + G C C PG+ G C + C G++G C + C C C+
Sbjct: 620 QPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPI 678
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
+G C C PGW G C Q C GF+G C H C C +G +C+ G C C GW G
Sbjct: 679 DGSC-QCFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGAC-HCTPGWTGLF 735
Query: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
C +C +G+DC VC CD SG+C C G G HC C PG G C Q
Sbjct: 736 CTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQL 795
Query: 419 CSC-HEDTCDPVTGACH 434
C C + TCD VTG C+
Sbjct: 796 CECMNNSTCDHVTGTCY 812
Score = 265 bits (676), Expect = 2e-70
Identities = 143/458 (31%), Positives = 186/458 (40%), Gaps = 105/458 (22%)
Query: 80 CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT 138
C + C C G+C C GY G C +CP +G C + C CH GQC T
Sbjct: 271 CSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTT 330
Query: 139 GQCTCHARRWGARCEHA--------------CQCQHG---TCHPRSGACRCEPGWWGAQC 181
G C C G RC+ C C +CHP +GAC C+PGW G C
Sbjct: 331 GACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC 390
Query: 182 ASAC-------------YCSATSRCDPQTGACLCH-------------AGWWGRSCNNQC 215
+C C + C TG C C AG +G +C++ C
Sbjct: 391 NESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSIC 450
Query: 216 ACNSS-PCEQQSGRCQCRER-------------TFGARCDRYCQCFRGR-CHPVDGTCAC 260
+CN+ C G C C+E T+G C+ C C G C P+DG+C+C
Sbjct: 451 SCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSC 510
Query: 261 EPGYRGKYCREPCPAGFYGLGCRRRCG--------------------------------- 287
PG+ G C PCP G +GL C C
Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGR 570
Query: 288 ---------QCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC-RDG 337
C+ C+ +G C C PG+ G C + C GFYG GC+ CP C
Sbjct: 571 WGPNCSVSCSCENGGSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSS 629
Query: 338 HACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGV 397
C+H++G C C G+ G C C+ G +G+DCA +C+ +G C G C C PG
Sbjct: 630 RPCHHISGIC-ECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGW 688
Query: 398 HGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACH 434
G C+ CPPG G C ACSCH +C GACH
Sbjct: 689 IGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACH 726
Score = 195 bits (496), Expect = 1e-49
Identities = 104/300 (34%), Positives = 132/300 (44%), Gaps = 53/300 (17%)
Query: 140 QCTCHARRWGARCEHAC--QCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQT 197
QC G C C +C HG C C CEPGW G C+S
Sbjct: 87 QCCPGYYESGDFCIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSG------------- 132
Query: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
C + WG C+N RCQC+ C+P+ G
Sbjct: 133 ----CDSDHWGPHCSN--------------RCQCQNGAL--------------CNPITGA 160
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
C C G+RG C E C G +G GC+ C QC+ C G CL C PG+ G C++
Sbjct: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPC-QCRHGASCDPRAGECL-CAPGYTGVYCEEL 218
Query: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
C G +G C RCP C++G C+H+TG+C C GW G C C GT+G++C+ C
Sbjct: 219 CPPGSHGAHCELRCP-CQNGGTCHHITGECA-CPPGWTGAVCAQPCPPGTFGQNCSQDCP 276
Query: 378 DCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHE-DTCDPVTGACHLE 436
G CD +G+C C+ G G C CP G G C+Q C CH C P TGAC E
Sbjct: 277 CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
Score = 140 bits (354), Expect = 4e-33
Identities = 76/211 (36%), Positives = 98/211 (46%), Gaps = 20/211 (9%)
Query: 233 ERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREP-CPAGFYGLG------CRRR 285
++ + RC F+ H + A G R Y R C G+Y G C
Sbjct: 47 DQIYYTRCTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEE 106
Query: 286 C--GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHV 343
C G+C C CEPGW G C C + +G CS+RC C++G CN +
Sbjct: 107 CVHGRCVSPDTCH--------CEPGWGGPDCSSGCDSDHWGPHCSNRCQ-CQNGALCNPI 157
Query: 344 TGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN 403
TG C C AG+ G RCE C+ GT+G+ C C CD ++G CLC+PG G +C
Sbjct: 158 TGACV-CAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCE 216
Query: 404 VTCPPGLHGADCAQACSCHE-DTCDPVTGAC 433
CPPG HGA C C C TC +TG C
Sbjct: 217 ELCPPGSHGAHCELRCPCQNGGTCHHITGEC 247
Score = 64.7 bits (156), Expect = 4e-10
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 72 GDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
G +CG + C+ ++C G+C CR G+ G +C+ +C +G C++LC C
Sbjct: 746 GKDCGRVCQCQNGASCDHIS-----GKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMN 800
Query: 131 HGQCEDVTGQCTCHARRWGARCEHA 155
+ C+ VTG C C G RC+ A
Sbjct: 801 NSTCDHVTGTCYCSPGFKGIRCDQA 825
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 288 bits (736), Expect = 2e-77
Identities = 156/472 (33%), Positives = 197/472 (41%), Gaps = 110/472 (23%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
CC G+ + G+ C V C C+ P C+C G+ G NC + C WGP C
Sbjct: 94 CCPGFYESGEMC---VPHCADKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT 149
Query: 124 ELCSCHPHGQCEDVTGQCTCHA--RRW-----------GARCEHACQCQHG-TCHPRSGA 169
C C C +TG C C A R W G C CQCQ+G TC +G
Sbjct: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
Query: 170 CRCEPGWWGA-------------QCASACYCSATSRCDPQTGACLCHAGW---------- 206
CRC PG+ GA QC C C C TG C C +GW
Sbjct: 210 CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCP 269
Query: 207 ---WGRSCNNQCAC-NSSPCEQQSGRCQCR-----ER--------TFGARCDRYCQCFRG 249
+G++C+ +C C N C+ +G+C C ER T+G C CQC G
Sbjct: 270 EGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG 329
Query: 250 -----------------------------------------------RCHPVDGTCACEP 262
CHP+ G CAC+P
Sbjct: 330 GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKP 389
Query: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF 322
G+ G YC E C GFYG C++ C C+ C G+C TC PG+ G C PC G
Sbjct: 390 GWSGLYCNETCSPGFYGEACQQIC-SCQNGADCDSVTGKC-TCAPGFKGIDCSTPCPLGT 447
Query: 323 YGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG 382
YG CS RC C++ C+ V G CT C AGW G C +C +GT+G C C G
Sbjct: 448 YGINCSSRC-GCKNDAVCSPVDGSCT-CKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGG 505
Query: 383 HCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGAC 433
C+ G C C+PG G C + C G +G +CA+ C C H D C P TG C
Sbjct: 506 ACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHC 557
Score = 280 bits (715), Expect = 5e-75
Identities = 147/431 (34%), Positives = 182/431 (42%), Gaps = 70/431 (16%)
Query: 63 TCCAGWRQQGDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD 121
TC G+ G+ C I C+ + C G+C C G+ G +C T CP +G +
Sbjct: 399 TCSPGF--YGEACQQICSCQNGADCDSVT-----GKCTCAPGFKGIDCSTPCPLGTYGIN 451
Query: 122 CKELCSCHPHGQCEDVTGQCTCHAR-------------RWGARCEHACQCQHG-TCHPRS 167
C C C C V G CTC A WG C CQC +G C+
Sbjct: 452 CSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLD 511
Query: 168 GACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW-------- 206
G C C PGW +G CA C CS C P TG C C GW
Sbjct: 512 GTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSV 571
Query: 207 -----WGRSCNNQCAC-NSSPCEQQSGRCQCRERTFGARCDRYC--------------QC 246
WG +C+ C C N + C G C+C G C R C QC
Sbjct: 572 CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC 631
Query: 247 FR--GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLT 304
G CH + G C C PG+ G C E CP+G +G C C C C + C
Sbjct: 632 VHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSC-Q 689
Query: 305 CEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCS 364
C PGW G+ C QPC +G C H C C +G C+ G+C +C GW G C +C
Sbjct: 690 CYPGWIGSDCSQPCPPAHWGPNCIHTCN-CHNGAFCSAYDGEC-KCTPGWTGLYCTQRCP 747
Query: 365 NGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HE 423
G YG+DCA +C CD SG+C C G G HC CP G +G C Q C C +
Sbjct: 748 LGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNN 807
Query: 424 DTCDPVTGACH 434
TCD +TG C+
Sbjct: 808 STCDHITGTCY 818
Score = 263 bits (673), Expect = 4e-70
Identities = 136/407 (33%), Positives = 177/407 (43%), Gaps = 72/407 (17%)
Query: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
TC G++ G +C C C + VC G C C+ G+ G +C +C
Sbjct: 429 TCAPGFK--GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC 486
Query: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------------CQH 160
P WG C C C G C + G CTC G +CE CQ C H
Sbjct: 487 PSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
Query: 161 GT-CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW 206
CHP +G CRC PGW WG C+ CYC + C P G C C G+
Sbjct: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF 606
Query: 207 WGRSCNN----------------QCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFR-- 248
G +C QC +S PC +G C C GA C+ C R
Sbjct: 607 RGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFG 666
Query: 249 ------------GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCT 296
G C+P+D +C C PG+ G C +PCP +G C C C C+
Sbjct: 667 KNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCN-CHNGAFCS 725
Query: 297 VAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIG 356
+G C C PGW G C Q C GFYG+ C+ C C++G C+H++G+CT C G++G
Sbjct: 726 AYDGEC-KCTPGWTGLYCTQRCPLGFYGKDCALICQ-CQNGADCDHISGQCT-CRTGFMG 782
Query: 357 DRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN 403
CE KC +GTYG C +C + CD +G C CSPG G C+
Sbjct: 783 RHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
Score = 260 bits (665), Expect = 3e-69
Identities = 151/483 (31%), Positives = 195/483 (40%), Gaps = 117/483 (24%)
Query: 63 TCCAGWRQQGDECGIAVCEGN--STCSENEVC-------VRPGECRCRHGYFGANCDTKC 113
+C +GW G CG EG CS+ C G+C C GY G C +C
Sbjct: 254 SCPSGW--MGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDEC 311
Query: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG------------ 161
P +G C E C C G+C V+G C C A G RCE A C G
Sbjct: 312 PVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCE-ARLCPEGLYGIKCDKRCPC 370
Query: 162 ------TCHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLC 202
+CHP SG C C+PGW +G C C C + CD TG C C
Sbjct: 371 HLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTC 430
Query: 203 HAGW-------------WGRSCNNQCAC-NSSPCEQQSGRCQCR-------------ERT 235
G+ +G +C+++C C N + C G C C+ T
Sbjct: 431 APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGT 490
Query: 236 FGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCG------- 287
+G C+ CQC G C+ +DGTC C PG+RG+ C PC G YGL C RC
Sbjct: 491 WGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC 550
Query: 288 -----------------------------------QCKGQQPCTVAEGRCLTCEPGWNGT 312
CK C+ +G C C PG+ GT
Sbjct: 551 HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC-ECAPGFRGT 609
Query: 313 KCDQPCATGFYGEGCSHRCPPC-RDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGED 371
C + C+ GFYG CS CP C C+H+TG C C G+ G C C +G +G++
Sbjct: 610 TCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALCNEVCPSGRFGKN 668
Query: 372 CAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDT-CDPVT 430
CA +C +G C+ C C PG G C+ CPP G +C C+CH C
Sbjct: 669 CAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYD 728
Query: 431 GAC 433
G C
Sbjct: 729 GEC 731
Score = 193 bits (490), Expect = 7e-49
Identities = 109/319 (34%), Positives = 146/319 (45%), Gaps = 37/319 (11%)
Query: 129 HPHGQ-----CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWW--GAQC 181
HP Q C D+ C R R + +HG +C PG++ G C
Sbjct: 50 HPFDQIYYTSCTDILNWFKCTRHRVSYRTAY----RHGEKTMYRRKSQCCPGFYESGEMC 105
Query: 182 ASACYCSAT-SRC-DPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGAR 239
C RC P T C C GW G +C++ C + +G
Sbjct: 106 VPHCADKCVHGRCIAPNT--CQCEPGWGGTNCSSACDGDH----------------WGPH 147
Query: 240 CDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
C CQC G C+P+ G C C G+RG C + C G YG C +RC QC+ C
Sbjct: 148 CTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRC-QCQNGATCDHV 206
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
G C C PG+ G C+ C G +G C RCP C++G C+HVTG+C+ C +GW+G
Sbjct: 207 TGEC-RCPPGYTGAFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTGECS-CPSGWMGTV 263
Query: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
C C G +G++C+ C G CD +G+C CSPG G C CP G +G CA+
Sbjct: 264 CGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAET 323
Query: 419 CSC-HEDTCDPVTGACHLE 436
C C + C V+GAC E
Sbjct: 324 CQCVNGGKCYHVSGACLCE 342
Score = 179 bits (453), Expect = 1e-44
Identities = 100/320 (31%), Positives = 128/320 (40%), Gaps = 70/320 (21%)
Query: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKC 113
TC GWR G++C + C CS + C G CRC G+ G +CD+ C
Sbjct: 515 TCAPGWR--GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVC 572
Query: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC--------------QCQ 159
WGP+C C C C G C C G C+ C QC
Sbjct: 573 AEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCV 632
Query: 160 H--GTCHPRSGACRCEPGWWGA-------------QCASACYCSATSRCDPQTGACLCHA 204
H G CH +G C C PG+ GA CA C C+ C+P +C C+
Sbjct: 633 HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYP 692
Query: 205 GW-------------WGRSCNNQCAC-NSSPCEQQSGRCQCRERT-------------FG 237
GW WG +C + C C N + C G C+C +G
Sbjct: 693 GWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG 752
Query: 238 ARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCT 296
C CQC G C + G C C G+ G++C + CP+G YG GCR+ C C C
Sbjct: 753 KDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQIC-DCLNNSTCD 811
Query: 297 VAEGRCLTCEPGWNGTKCDQ 316
G C C PGW G +CDQ
Sbjct: 812 HITGTCY-CSPGWKGARCDQ 830
Score = 116 bits (290), Expect = 1e-25
Identities = 60/208 (28%), Positives = 82/208 (39%), Gaps = 41/208 (19%)
Query: 96 GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA---------- 145
G C C G+ GA C+ CP +G +C +C+C +G C + C C+
Sbjct: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
Query: 146 ---RRWGARCEHACQCQHGT-CHPRSGACRCEPGW-------------WGAQCASACYCS 188
WG C H C C +G C G C+C PGW +G CA C C
Sbjct: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ 762
Query: 189 ATSRCDPQTGACLCHAGWWGRSCNNQC--------------ACNSSPCEQQSGRCQCRER 234
+ CD +G C C G+ GR C +C N+S C+ +G C C
Sbjct: 763 NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPG 822
Query: 235 TFGARCDRYCQCFRGRCHPVDGTCACEP 262
GARCD+ G + + T P
Sbjct: 823 WKGARCDQAGVIIVGNLNSLSRTSTALP 850
Score = 89.0 bits (219), Expect = 2e-17
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 19/119 (15%)
Query: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
C + CS + GEC+C G+ G C +CP F+G DC +C C C+ ++G
Sbjct: 718 CHNGAFCSAYD-----GECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG 772
Query: 140 QCTCHARRWGARCEHACQC--------------QHGTCHPRSGACRCEPGWWGAQCASA 184
QCTC G CE C + TC +G C C PGW GA+C A
Sbjct: 773 QCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
Score = 68.9 bits (167), Expect = 2e-11
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 72 GDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
G +C I C+ + C G+C CR G+ G +C+ KCP +G C+++C C
Sbjct: 752 GKDCALICQCQNGADCDHIS-----GQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN 806
Query: 131 HGQCEDVTGQCTCHARRWGARCEHA 155
+ C+ +TG C C GARC+ A
Sbjct: 807 NSTCDHITGTCYCSPGWKGARCDQA 831
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 275 bits (702), Expect = 2e-73
Identities = 142/442 (32%), Positives = 185/442 (41%), Gaps = 71/442 (16%)
Query: 60 QVPTCCAGWRQQGDECGIAVCEGNS--------TCSENEVCVRP-GECRCRHGYFGANCD 110
Q C + G C ++ +G S +C V P G C C G+ G C
Sbjct: 201 QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICS 260
Query: 111 TKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCH-------------ARRWGARCEHACQ 157
CP F GP+C + C CH G C+ TGQC C R+G C C
Sbjct: 261 LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCD 320
Query: 158 CQ-HGTCHPRSGACRCE--------------PGWWGAQCASACYCSA--TSRCDPQTGAC 200
C C P +GAC CE G++G C + C C + C P G C
Sbjct: 321 CAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGEC 380
Query: 201 LCHAGWWGRSCNNQC--------------ACNSSPCEQQSGRCQCRER------------ 234
C GW G CN C + C+ SG CQC
Sbjct: 381 SCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPP 440
Query: 235 -TFGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQ 292
T+G C C C C P+DG C C+ G++ C PCP G +G C C QC +
Sbjct: 441 DTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASC-QCAHE 499
Query: 293 QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNA 352
C+ G C TC PGW+G C PC G +GEGC+ RC C C+ V G+C +C A
Sbjct: 500 AVCSPQTGAC-TCTPGWHGAHCQLPCPKGQFGEGCASRCD-CDHSDGCDPVHGRC-QCQA 556
Query: 353 GWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHG 412
GW+G RC C G +G +C+ C G C ++G C+C+PG GP C +C PG +G
Sbjct: 557 GWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYG 616
Query: 413 ADCAQACSCHEDTCDPVTGACH 434
C + C P G C+
Sbjct: 617 KRCVPCKCANHSFCHPSNGTCY 638
Score = 251 bits (640), Expect = 3e-66
Identities = 199/716 (27%), Positives = 266/716 (37%), Gaps = 139/716 (19%)
Query: 80 CEGNSTCS-ENEVCVRP--GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCED 136
C+ TC E+ + P GEC C G+ G +C+ CP+ GP C+E C C G C+
Sbjct: 359 CQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQA 418
Query: 137 VTGQCTC-------HARR------WGARCEHACQCQHG-TCHPRSGACRCEPGW------ 176
+G C C H +G C C C++ C P G C C+ GW
Sbjct: 419 TSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCS 478
Query: 177 -------WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRC 229
WG C ++C C+ + C PQTGAC C GW G C +
Sbjct: 479 VPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHC----------------QL 522
Query: 230 QCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQ 288
C + FG C C C C PV G C C+ G+ G C CP G +G+ C C
Sbjct: 523 PCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTC-T 581
Query: 289 CKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCR-DGHACNHVTGKC 347
CK C G C+ C PG+ G C + C G YG+ RC PC+ H+ H +
Sbjct: 582 CKNGGTCLPENGNCV-CAPGFRGPSCQRSCQPGRYGK----RCVPCKCANHSFCHPSNGT 636
Query: 348 TRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCP 407
C AGW G C C G +GE+CA C G C Q G C+C G G HC CP
Sbjct: 637 CYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCP 696
Query: 408 PGLHGADCAQACSCHE-DTCDPVTGAC-------------------------HLETNQRK 441
G GA+C+Q C C + C P TGAC + N
Sbjct: 697 LGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMPTTPVAYNSLG 756
Query: 442 GVMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLGRKKAPHRLCGRFSRISMKLPR 501
V+G L L+V L+ +G +GK+ ++ GR +P
Sbjct: 757 AVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYS--------SGRLDGSEYVMPD 808
Query: 502 IPLRRQKLPKVVVAHHDLDNTLNCSFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCV 561
+P H TL+ PP + P P ++S +
Sbjct: 809 VPPSYSHYYSNPSYH-----TLSQCSPNPPPPNKVPGPLFASLQN--------------- 848
Query: 562 PHEEAPAESRDPEVPTVPAE---APAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGP 618
P A+ D T+PA+ P P PL +S D S S GP
Sbjct: 849 PERPGGAQGHDNHT-TLPADWKHRREPPPGPLDRGSS---------RLDRSYSYSYSNGP 898
Query: 619 GGALYARVARREARPARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAG 678
G + E A + LS + P P + S++ K
Sbjct: 899 GPFYNKGLISEEELGA----SVASLSSENPYATIRDLPSLPGGPRESSYMEMK------- 947
Query: 679 RAPSPPPPGSEAAPSPSKRKRTPS-DKSAHTVEHGSPRTRD------PTPRPPGLP 727
PS PP S+R+R P + + T E SP D P PPGLP
Sbjct: 948 GPPSGSPPRQPPQFWDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLP 1003
Score = 248 bits (633), Expect = 2e-65
Identities = 137/423 (32%), Positives = 184/423 (43%), Gaps = 55/423 (13%)
Query: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCD 110
R V + Q CC G+ + C + +C C CV P +C+C G+ G +C
Sbjct: 77 RQVVKTDHRQRLQCCHGFYESRGFC-VPLCA--QECVHGR-CVAPNQCQCVPGWRGDDCS 132
Query: 111 TKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARR-------------WGARCEHACQ 157
++C WGP C + CSC + C+ +G C+C + +G C+ CQ
Sbjct: 133 SECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQ 192
Query: 158 CQHGTCHPRSGACRCEPGWWGAQCASAC-------YCSATSRCD-------PQTGACLCH 203
C C P++GAC C G C +C +C +T C PQ G+C C
Sbjct: 193 CHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ-GSCSCP 251
Query: 204 AGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEP 262
GW G C+ C E G C + C+C G C G C C P
Sbjct: 252 PGWMGTICS----------------LPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAP 295
Query: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC-DQPCATG 321
GY G CRE CP G +G C C C C A G CL CE G+ G +C D+ C G
Sbjct: 296 GYTGDRCREECPVGRFGQDCAETC-DCAPDARCFPANGACL-CEHGFTGDRCTDRLCPDG 353
Query: 322 FYGEGCSHRCPPCRDGH-ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCG 380
FYG C C R+ +C+ + G+C+ C GW G C C T+G C C
Sbjct: 354 FYGLSCQAPCTCDREHSLSCHPMNGECS-CLPGWAGLHCNESCPQDTHGPGCQEHCLCLH 412
Query: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACHLETNQ 439
G C SG C C+PG GPHC CPP +G +C+ CSC C P+ G C +
Sbjct: 413 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGW 472
Query: 440 RKG 442
++G
Sbjct: 473 QRG 475
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query: 57 PGSQVPTCCAGWRQQGDECGIAV--------CEGNSTCSENEVC-VRPGECRCRHGYFGA 107
P + C AGW G +C C C C + G C C G+ G
Sbjct: 632 PSNGTCYCLAGWT--GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGH 689
Query: 108 NCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ 157
+C CP +G +C + C C P +C TG C C GA C Q
Sbjct: 690 HCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQ 739
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 158 bits (399), Expect = 2e-38
Identities = 143/437 (32%), Positives = 177/437 (40%), Gaps = 118/437 (27%)
Query: 72 GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTK-CPRQFWGPDCKELCSCHP 130
G++CG C + C E CV G C C GY G +C T+ CPR C
Sbjct: 334 GEDCGTRSCPWD--CGEGGRCV-DGRCVCWPGYTGEDCSTRTCPRD-----------CRG 379
Query: 131 HGQCEDVTGQCTCHARRWGARCE-HAC--QC-QHGTCHPRSGACRCEPGWWGAQCAS-AC 185
G+CED G+C C G C +C C Q G C G C C PG+ G C S AC
Sbjct: 380 RGRCED--GECICDTGYSGDDCGVRSCPGDCNQRGRCE--DGRCVCWPGYTGTDCGSRAC 435
Query: 186 Y--CSATSRCDPQTGACLCHAGWWG-----RSCNNQCACNSSPCEQQSGRCQCRERTFGA 238
C RC+ G C+C+AG+ G RSC C CE SGRC C G
Sbjct: 436 PRDCRGRGRCE--NGVCVCNAGYSGEDCGVRSCPGDCR-GRGRCE--SGRCMCWPGYTGR 490
Query: 239 RCD-RYC--QCFRGRCHPVDGTCACEPGYRGKYC---REP---------------CPAGF 277
C R C C RGR VDG C C PG+ G+ C R P C AG+
Sbjct: 491 DCGTRACPGDC-RGRGRCVDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGY 549
Query: 278 YGLGCRRRC--GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP------------------ 317
G C R G C+G+ C +GRC+ CE G++G C
Sbjct: 550 SGEDCSTRSCPGGCRGRGQC--LDGRCV-CEDGYSGEDCGVRQCPNDCSQHGVCQDGVCI 606
Query: 318 CATGFYGEGCSHR-CPP-CRDGHACNHVTGKCTRCNAGWIGDRCETK------------- 362
C G+ E CS R CP C C G+C C+ G+ G C T+
Sbjct: 607 CWEGYVSEDCSIRTCPSNCHGRGRCEE--GRCL-CDPGYTGPTCATRMCPADCRGRGRCV 663
Query: 363 -----CSNGTYGEDC------AFVC-ADCGSGHCDFQSGRCLCSPGVHGPHCNV-TCPPG 409
C G GEDC A C CG ++G+C+C G GP C + TCP
Sbjct: 664 QGVCLCHVGYGGEDCGQEEPPASACPGGCGPREL-CRAGQCVCVEGFRGPDCAIQTCP-- 720
Query: 410 LHGADCAQACSCHEDTC 426
DC CH+ +C
Sbjct: 721 ---GDCRGRGECHDGSC 734
Score = 127 bits (319), Expect = 4e-29
Identities = 117/389 (30%), Positives = 147/389 (37%), Gaps = 115/389 (29%)
Query: 86 CSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHA 145
C++ CVR G C C GY G +C W P C C G+C V G C C A
Sbjct: 191 CNDQGRCVR-GRCVCFPGYTGPSCG-------W-PSCPG--DCQGRGRC--VQGVCVCRA 237
Query: 146 RRWGARC-EHACQ---CQHGTCHPRSGACRCEPGWWGAQCASACY---CSATSRCDPQTG 198
G C + +C Q G C G C C+PG+ G C CS RC+ G
Sbjct: 238 GFSGPDCSQRSCPRGCSQRGRCE--GGRCVCDPGYTGDDCGMRSCPRGCSQRGRCE--NG 293
Query: 199 ACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGAR-CDRYCQCFRGRCHPVDGT 257
C+C+ G+ G C G R C R C RGRC DG
Sbjct: 294 RCVCNPGYTGEDC-------------------------GVRSCPRGCSQ-RGRCK--DGR 325
Query: 258 CACEPGYRGKYC------------------REPCPAGFYGLGCRRRC--GQCKGQQPCTV 297
C C+PGY G+ C R C G+ G C R C+G+ C
Sbjct: 326 CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRTCPRDCRGRGRC-- 383
Query: 298 AEGRCLTCEPGWNGTKCDQ------------------PCATGFYGEGCSHR-CP-PCRDG 337
+G C+ C+ G++G C C G+ G C R CP CR
Sbjct: 384 EDGECI-CDTGYSGDDCGVRSCPGDCNQRGRCEDGRCVCWPGYTGTDCGSRACPRDCRGR 442
Query: 338 HACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGV 397
C + G C CNAG+ G+ C + G DC G G C +SGRC+C PG
Sbjct: 443 GRCEN--GVCV-CNAGYSGEDCGVRSCPG----DCR------GRGRC--ESGRCMCWPGY 487
Query: 398 HGPHCNVTCPPGLHGADCAQACSCHEDTC 426
G C PG DC C + C
Sbjct: 488 TGRDCGTRACPG----DCRGRGRCVDGRC 512
Score = 102 bits (255), Expect = 1e-21
Identities = 79/247 (31%), Positives = 100/247 (40%), Gaps = 50/247 (20%)
Query: 49 RGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGAN 108
RG +C V C AG+ G++C C G C C+ G C C GY G +
Sbjct: 533 RGHGLCE---DGVCVCDAGY--SGEDCSTRSCPGG--CRGRGQCL-DGRCVCEDGYSGED 584
Query: 109 CDTK-CPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQH--GTCHP 165
C + CP C HG C+D G C C W C + CH
Sbjct: 585 CGVRQCPND-----------CSQHGVCQD--GVCIC----WEGYVSEDCSIRTCPSNCHG 627
Query: 166 RS----GACRCEPGWWGAQCASACY---CSATSRCDPQTGACLCHAGWWGRSCNNQ---- 214
R G C C+PG+ G CA+ C RC G CLCH G+ G C +
Sbjct: 628 RGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRC--VQGVCLCHVGYGGEDCGQEEPPA 685
Query: 215 --CACNSSPCEQ-QSGRCQCRERTFGARCD-RYC--QCF-RGRCHPVDGTCACEPGYRGK 267
C P E ++G+C C E G C + C C RG CH DG+C C+ GY G+
Sbjct: 686 SACPGGCGPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGRGECH--DGSCVCKDGYAGE 743
Query: 268 YCREPCP 274
C E P
Sbjct: 744 DCGEEVP 750
Score = 84.0 bits (206), Expect = 6e-16
Identities = 74/247 (29%), Positives = 94/247 (38%), Gaps = 58/247 (23%)
Query: 209 RSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKY 268
+ QC P Q+G Q RT C + RC TC+CEPG+ G
Sbjct: 115 KGLKEQCTGGCCPASAQAGTGQTDVRTL---CSLHGVFDLSRC-----TCSCEPGWGGPT 166
Query: 269 CREPCPAGFYGLGCRRRCG----QCKGQQPCTVAEGRCLTCEPGWNGTKCDQP------- 317
C +P A G C Q C GRC+ C PG+ G C P
Sbjct: 167 CSDPTDAEIPPSSPPSASGSCPDDCNDQGRC--VRGRCV-CFPGYTGPSCGWPSCPGDCQ 223
Query: 318 -----------CATGFYGEGCSHR-CP-PCRDGHACNHVTGKCTRCNAGWIGDRCETKCS 364
C GF G CS R CP C C G+C C+ G+ GD C +
Sbjct: 224 GRGRCVQGVCVCRAGFSGPDCSQRSCPRGCSQRGRCE--GGRCV-CDPGYTGDDCGMR-- 278
Query: 365 NGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNV-TCPPGLHGADCAQACSCHE 423
C C+ G C ++GRC+C+PG G C V +CP G C+Q C +
Sbjct: 279 ------SCPRGCSQ--RGRC--ENGRCVCNPGYTGEDCGVRSCPRG-----CSQRGRCKD 323
Query: 424 D--TCDP 428
CDP
Sbjct: 324 GRCVCDP 330
Score = 30.4 bits (67), Expect = 7.4
Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 13/137 (9%)
Query: 575 VPTVPAEAPAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYA--RVARREAR 632
V TV AP P+P+P+ P E A+ S S + +GP + R A+ + +
Sbjct: 3244 VSTVGITAPLPTPLPV-EPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQ 3302
Query: 633 PARARGEIGGLSLSPSPERRKPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAP 692
G++ +++S DPA K K + G + G P + P
Sbjct: 3303 AVPVSGDLRAVAVSGL---------DPARKYKF-LLFGLQNGKRHGPVPVEARTAPDTKP 3352
Query: 693 SPSKRKRTPSDKSAHTV 709
SP + T +D + +V
Sbjct: 3353 SPRLGELTVTDATPDSV 3369
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 140 bits (352), Expect = 7e-33
Identities = 135/429 (31%), Positives = 173/429 (40%), Gaps = 50/429 (11%)
Query: 22 SPLLPSLLLLLLLWMLPDTVAPQ-----ELNPRGRNVCRAPGSQVPTC--CAGWRQQGDE 74
+PLL SL L+ LP PQ E NP G PG C CA
Sbjct: 766 APLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP 825
Query: 75 CGIAVCEGNSTCSENEVCVRP-GECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHG 132
G C+ + + + +C + G+C CR G FG CD +C R WG P C+ C C+ H
Sbjct: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCD-RCQRGQWGFPSCRP-CVCNGHA 883
Query: 133 -QCEDVTGQCT-CHARRWGARCEHACQCQHGTCH-PRSGACR-CE-PGWWGAQ--CASAC 185
+C TG C C G CE HG P G CR C P G+Q A++C
Sbjct: 884 DECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSC 943
Query: 186 YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGA------R 239
+ S Q C C AG+ G C + + GRCQ E +
Sbjct: 944 HQDEYS----QQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDA 999
Query: 240 CDRYC-QCFRGRCHPVDGTCA-CEPGYRGKYCREPCPAGFYG-LGCRRRCGQCKGQQPCT 296
CD + QC R H CA C+PG+ G+ R+ C LG + Q C
Sbjct: 1000 CDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCD 1059
Query: 297 VAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC------RDGHACNHVTGKCTRC 350
+ G+C C P G CD+ CA F+ H C PC G CN TG+C C
Sbjct: 1060 PSSGQC-PCLPNVQGPSCDR-CAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HC 1116
Query: 351 NAGWIGDRCETKCSNGTYGEDCAFVC--ADCGS-----GHCDFQSGRCLCSPGVHGPHCN 403
AG+ G C ++C +G D C DC S C +G C C PGV G C+
Sbjct: 1117 RAGFGGRTC-SECQELHWG-DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD 1174
Query: 404 VTCPPGLHG 412
C G G
Sbjct: 1175 -QCARGFSG 1182
Score = 125 bits (315), Expect = 1e-28
Identities = 103/343 (30%), Positives = 127/343 (37%), Gaps = 97/343 (28%)
Query: 182 ASACYC----SATSRCDPQTGACLCHAGWWGRSCN--------------NQCACN----- 218
A C C S +S C+P G CLC G GR C+ C C+
Sbjct: 780 ALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGAL 839
Query: 219 SSPCEQQSGRCQCRERTFGARCDR--------------YCQCFRGRCHPVDGTC-ACEPG 263
SS CE+ SG+C CR FG RCDR C C+ G C C
Sbjct: 840 SSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
Query: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGR-------------------CLT 304
G++C E C AGF+G GQC+ PC EG
Sbjct: 900 TGGEHC-ERCIAGFHGDPRLPYGGQCR---PCPCPEGPGSQRHFATSCHQDEYSQQIVCH 955
Query: 305 CEPGWNGTKCDQPCATGFYGEGC--SHRCPPCR--------DGHACNHVTGKCTRCNAGW 354
C G+ G +C + CA G +G+ RC C D AC+ TG+C RC
Sbjct: 956 CRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHT 1014
Query: 355 IGDRCETKCSNGTYGEDCAFVCADCGSG---------------HCDFQSGRCLCSPGVHG 399
G C C G +G+ C C HCD SG+C C P V G
Sbjct: 1015 EGPHC-AHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQG 1073
Query: 400 PHCNVTCPP---GLHGADCAQACSCHED-----TCDPVTGACH 434
P C+ C P L Q C+CH TC+ TG CH
Sbjct: 1074 PSCD-RCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCH 1115
Score = 55.5 bits (132), Expect = 2e-07
Identities = 77/294 (26%), Positives = 100/294 (34%), Gaps = 78/294 (26%)
Query: 185 CYCSA-TSRCDPQTGA-----------CLCHAGWWGRSCNNQCA-----CNSSPCEQQSG 227
C+C S C P GA C+C G +C QC P E
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCE-QCQDFYRDLPWRPAEDGHS 341
Query: 228 ----RCQCRERTFGARCDRYCQCFRGRCHPVDGTC-ACEPGYRGKYCREPCPAGFYGLGC 282
+C+C T D G G C C+ G++C E C FY
Sbjct: 342 HACRKCECHGHTHSCHFDMAVYLASGNVS--GGVCDGCQHNTAGRHC-ELCRPFFY---- 394
Query: 283 RRRCGQCKGQQPCTVAEGRCLTCEP--GWNGTKCDQPCATGFYGEGCSHRCPPCRDGHAC 340
R + C R C+P +G +CD SH D A
Sbjct: 395 RDPTKDLRDPAVC-----RSCDCDPMGSQDGGRCD------------SH------DDPAL 431
Query: 341 NHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA--FVCADC---------GSGHCDFQSG 389
V+G+C RC +G RC+ +C +G +G + C C GS CD SG
Sbjct: 432 GLVSGQC-RCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
Query: 390 RCLCSPGVHGPHCNVTCPPG----LHGADCAQACSCH-----EDTCDPVTGACH 434
C C V G C+ C PG H + C C + CD TG CH
Sbjct: 490 SCYCKRLVTGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCH 542
Score = 54.7 bits (130), Expect = 4e-07
Identities = 70/273 (25%), Positives = 93/273 (34%), Gaps = 80/273 (29%)
Query: 96 GECRCRHGYFGANCDTKCPRQF----WGPD-------CKELCSCHPHGQ-CEDVTGQCTC 143
G C C+H G NC+ +C + W P C++ C CH H C
Sbjct: 308 GACICKHNTRGLNCE-QCQDFYRDLPWRPAEDGHSHACRK-CECHGHTHSCHFDMAVYLA 365
Query: 144 HARRWGARCEHACQCQHGT-------CHP----------RSGA----CRCEPGWWGAQCA 182
G C+ CQH T C P R A C C+P G+Q
Sbjct: 366 SGNVSGGVCDG---CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDP--MGSQDG 420
Query: 183 SAC---------YCSATSRCDPQ---TGACLCHAGWWGRSCNNQ-----CACN------- 218
C S RC T C G++G S +++ C CN
Sbjct: 421 GRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPG 480
Query: 219 SSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDG--TCACEPGYRGKYCREPCPAG 276
S+PC+ SG C C+ G CDR G H + G C C+ G G
Sbjct: 481 STPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVG------------G 528
Query: 277 FYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGW 309
C GQC +Q + RC +PG+
Sbjct: 529 ALDPQCDEGTGQCHCRQ--HMVGRRCEQVQPGY 559
Score = 49.3 bits (116), Expect = 2e-05
Identities = 46/200 (23%), Positives = 66/200 (33%), Gaps = 68/200 (34%)
Query: 54 CRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGEC-RCRHGYFGANCDTK 112
C GSQ C D+ + + G C E+ V R C +CR G+FG + +
Sbjct: 412 CDPMGSQDGGRC----DSHDDPALGLVSGQCRCKEHVVGTR---CQQCRDGFFGLSISDR 464
Query: 113 CPRQFWGPDCKELCSCHPHG------QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPR 166
C+ C C+ G C+ +G C C G C+
Sbjct: 465 L-------GCRR-CQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD------------- 503
Query: 167 SGACRCEPGWWGAQ----CASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPC 222
RC PG WG C C DPQ C
Sbjct: 504 ----RCLPGHWGLSHDLLGCRPCDCDVGGALDPQ-------------------------C 534
Query: 223 EQQSGRCQCRERTFGARCDR 242
++ +G+C CR+ G RC++
Sbjct: 535 DEGTGQCHCRQHMVGRRCEQ 554
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 140 bits (352), Expect = 7e-33
Identities = 149/548 (27%), Positives = 190/548 (34%), Gaps = 182/548 (33%)
Query: 52 NVCRAPGSQVPTCCAGWRQQ---------GDECGIAVCEGNSTCS--ENEVCVRP----- 95
N C G CC G+ QQ +EC C G++T + EV R
Sbjct: 327 NTC---GGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVDRRRASQSL 383
Query: 96 -------GEC-RCRHGYFGANCDTKCPRQFWGPD--------CKELCSCHPH---GQCED 136
G C C+H G NC+ P + P+ C+ C+C G CED
Sbjct: 384 DGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRR-CNCESDFTDGTCED 442
Query: 137 VTGQCTCHARRWGARCEHA--------------------------------CQC-----Q 159
+TG+C C G RC+ C C Q
Sbjct: 443 LTGRCYCRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQ 502
Query: 160 HGTCH--PRSGACRCEPGWWGAQC-----------ASACYCS----ATSRCDPQTGACLC 202
C PR G C C+P + G C C CS A RCDP TG C C
Sbjct: 503 GNACRKDPRVGRCLCKPNFQGTHCELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRC 562
Query: 203 HAGWWGRSCNNQCA-----------CNSSPCE------QQSGRCQCRERTFGARCDR--- 242
G+ G +C+ +CA C SP ++GRC C+ G CDR
Sbjct: 563 RVGFEGATCD-RCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRP 621
Query: 243 ----YCQCFRGRCHP---------VDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQC 289
+ C C P G C C PGY G C+E C GF+G C C
Sbjct: 622 GYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPSCVPC-HC 679
Query: 290 KGQ----QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYG-----EGCSHRC--------- 331
+ C G+C +C P G +CD C G Y G H
Sbjct: 680 SAEGSLHAACDPRSGQC-SCRPRVTGLRCDT-CVPGAYNFPYCEAGSCHPAGLAPVDPAL 737
Query: 332 PPCRDGHACN-HVTG-KCTRCNAGWIG------DRCETKCS---NGTYGEDCAFVCADCG 380
P + C HV G C RC G+ G + C T+CS GT G G
Sbjct: 738 PEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGC-TRCSCDLRGTLG----------G 786
Query: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCA-----QACSCH-----EDTCDPVT 430
C +G+C C P V G C +C G G D A ++C C +C+P T
Sbjct: 787 VAECQPGTGQCFCKPHVCGQAC-ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRT 845
Query: 431 GACHLETN 438
G C N
Sbjct: 846 GVCRCRPN 853
Score = 122 bits (305), Expect = 2e-27
Identities = 121/461 (26%), Positives = 157/461 (34%), Gaps = 126/461 (27%)
Query: 76 GIAVCEGNSTCSENEVCVRPG--ECRCRHGYFGANCDTKCP---RQFWGP----DCKELC 126
G VC G++ + + P +C C+H G CD CP +Q W P E
Sbjct: 298 GRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQ 357
Query: 127 SCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACY 186
SC+ +G D RR A Q GT C+ G C
Sbjct: 358 SCNCYGHATDCYYDPEVDRRR-------ASQSLDGTYQGGGVCIDCQHHTTGVNCERCLP 410
Query: 187 CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQC 246
S P +C R CN + CE +GRC CR G RCD +
Sbjct: 411 GFYRSPNHPLDSPHVC------RRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEG 464
Query: 247 FRG--RCHPVD-------------------------------------GTCACEPGYRGK 267
F G C+P G C C+P ++G
Sbjct: 465 FTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGT 524
Query: 268 YCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC------LTCEPGWNGTKCDQPCATG 321
+C E C GFYG GC+ C+ P VA+ RC C G+ G CD+ CA G
Sbjct: 525 HC-ELCAPGFYGPGCQ----PCQCSSP-GVADDRCDPDTGQCRCRVGFEGATCDR-CAPG 577
Query: 322 FY----------------GEGCSH-------------RCPPCRDGH----ACNHVT---- 344
++ EGC C CR G+ C T
Sbjct: 578 YFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPR 637
Query: 345 ---------GKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH----CDFQSGRC 391
G RC G+ G C+ +CS G +G C G CD +SG+C
Sbjct: 638 GALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQC 696
Query: 392 LCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGA 432
C P V G C+ TC PG + +A SCH PV A
Sbjct: 697 SCRPRVTGLRCD-TCVPGAYNFPYCEAGSCHPAGLAPVDPA 736
Score = 118 bits (295), Expect = 3e-26
Identities = 111/351 (31%), Positives = 130/351 (37%), Gaps = 80/351 (22%)
Query: 113 CPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHG---TCHPRSGA 169
CP + G C+E C P G DV G RC CQC HG C P SG
Sbjct: 1833 CPASYRGDSCQE---CAP-GFYRDVKGLFL-------GRCV-PCQC-HGHSDRCLPGSGV 1879
Query: 170 C-RCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGR 228
C C+ GA C +SR DP S+PC
Sbjct: 1880 CVDCQHNTEGAHCERCQAGFVSSRDDP-----------------------SAPCVS---- 1912
Query: 229 CQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYG----LGCRR 284
C C C GR C C+PGY G C E C GF+G LG
Sbjct: 1913 CPCPLSVPSNNFAEGCVLRGGRTQ-----CLCKPGYAGASC-ERCAPGFFGNPLVLGSSC 1966
Query: 285 RCGQCKGQ-------QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEG-----CSH-RC 331
+ C G C G C C G +C+ CA GFYG C+ C
Sbjct: 1967 QPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTRCDC 2025
Query: 332 PPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG------HCD 385
PC AC+ +G C C AG G RC+ +C G +G D C C G C
Sbjct: 2026 TPCGT-EACDPHSGHCL-CKAGVTGRRCD-RCQEGHFGFDGCGGCRPCACGPAAEGSECH 2082
Query: 386 FQSGRCLCSPGVHGPHCNVTCPPGLHG--ADCAQACSCHEDTCDPVTGACH 434
QSG+C C PG GP C C PG G + C C CDP TG C+
Sbjct: 2083 PQSGQCHCRPGTMGPQCR-ECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCN 2132
Score = 107 bits (267), Expect = 5e-23
Identities = 88/300 (29%), Positives = 109/300 (36%), Gaps = 86/300 (28%)
Query: 50 GRNVC-----RAPGSQVPTCCAGWRQQGDE---------CGIAVCEGNSTCSENEVCVRP 95
G VC G+ C AG+ D+ C ++V N E CV
Sbjct: 1876 GSGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFA----EGCVLR 1931
Query: 96 G---ECRCRHGYFGANCDTKCPRQFWGP-----DCKELCSCHPHGQ-------CEDVTGQ 140
G +C C+ GY GA+C+ P F P C+ C C +G C+ +TG
Sbjct: 1932 GGRTQCLCKPGYAGASCERCAPGFFGNPLVLGSSCQP-CDCSGNGDPNLLFSDCDPLTGA 1990
Query: 141 CT-CHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGA 199
C C G RCE +G RC+ C T CDP +G
Sbjct: 1991 CRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCD-----------CTPCGTEACDPHSGH 2039
Query: 200 CLCHAGWWGRSCNN---------------QCACN----SSPCEQQSGRCQCRERTFGARC 240
CLC AG GR C+ CAC S C QSG+C CR T G +C
Sbjct: 2040 CLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQC 2099
Query: 241 D--------------RYCQCFRGRCHPVDGTCACEPGYRGKYC-------REPCPAGFYG 279
R CQC GRC P G C C PG G+ C + P P G G
Sbjct: 2100 RECAPGYWGLPEQGCRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVG 2159
Score = 101 bits (251), Expect = 3e-21
Identities = 92/286 (32%), Positives = 114/286 (39%), Gaps = 60/286 (20%)
Query: 200 CLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCF--RGRCHPVDGT 257
CLC A + G SC +CA G + + F RC CQC RC P G
Sbjct: 1831 CLCPASYRGDSCQ-ECA---------PGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGV 1879
Query: 258 CA-CEPGYRGKYCREPCPAGFYG-----------LGCRRRCGQCKGQQPCTVAEGR--CL 303
C C+ G +C E C AGF C + C + GR CL
Sbjct: 1880 CVDCQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCL 1938
Query: 304 TCEPGWNGTKCDQPCATGFYGEGC--SHRCPPCR-DGHA--------CNHVTGKCTRCNA 352
C+PG+ G C++ CA GF+G C PC G+ C+ +TG C C
Sbjct: 1939 -CKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLR 1996
Query: 353 GWIGDRCETKCSNGTYGE-----DCAFV-CADCGSGHCDFQSGRCLCSPGVHGPHCNVTC 406
G RCE C+ G YG +C C CG+ CD SG CLC GV G C+ C
Sbjct: 1997 HTTGPRCEI-CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCD-RC 2054
Query: 407 PPGLHGAD-------CAQACSCHEDTCDPVTGACHLETNQRKGVMG 445
G G D CA + C P +G CH R G MG
Sbjct: 2055 QEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHC----RPGTMG 2096
Score = 95.1 bits (235), Expect = 2e-19
Identities = 76/283 (26%), Positives = 104/283 (36%), Gaps = 59/283 (20%)
Query: 38 PDTVAPQELNPRGRNVCRAPGSQVPTC--CAGWRQQGDECGIAVCEGNSTCSENEVCVRP 95
P P+ + GR +C+ P P C C C C+ +++C
Sbjct: 591 PAGTLPEGCDEAGRCLCQ-PEFAGPHCDRCRPGYHGFPNCQACTCDPRGAL--DQLCGAG 647
Query: 96 GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP----HGQCEDVTGQCTCHARRWGAR 151
G CRCR GY G C P P C C C H C+ +GQC+C R G R
Sbjct: 648 GLCRCRPGYTGTACQECSPGFHGFPSCVP-CHCSAEGSLHAACDPRSGQCSCRPRVTGLR 706
Query: 152 CEHACQ-------CQHGTCHPRSGACRCEPGWWGAQCASACYCSATS-RCDPQTGACLCH 203
C+ C+ G+CHP +G +P AQ C CD C
Sbjct: 707 CDTCVPGAYNFPYCEAGSCHP-AGLAPVDPALPEAQVPCMCRAHVEGPSCDR------CK 759
Query: 204 AGWWGRSCNN-----QCACNS-------SPCEQQSGRCQCRERTFGARCD---------- 241
G+WG S +N +C+C+ + C+ +G+C C+ G C
Sbjct: 760 PGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLD 819
Query: 242 -------RYCQCFRG-----RCHPVDGTCACEPGYRGKYCREP 272
R C+C G C P G C C P +G C EP
Sbjct: 820 QADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEP 862
Score = 89.4 bits (220), Expect = 1e-17
Identities = 90/321 (28%), Positives = 113/321 (35%), Gaps = 80/321 (24%)
Query: 137 VTGQCTCHARRWGARCEHA-------CQCQHGTCHPRSGAC-RCEPG-----WWGAQCAS 183
+ G+C CH + C CQH TC G C RC PG W A S
Sbjct: 296 IGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTC---GGTCDRCCPGFNQQPWKPATANS 352
Query: 184 ACYCSATSRCDPQTGACLCHAG--WWGRSCNNQCACNSSPCEQQSGRC--QCRERTFGAR 239
A C + + C HA ++ + + A S Q G C+ T G
Sbjct: 353 ANECQSCN--------CYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVN 404
Query: 240 CDRYCQCF-RGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
C+R F R HP+D C R C + F C G+C
Sbjct: 405 CERCLPGFYRSPNHPLDSPHVCR--------RCNCESDFTDGTCEDLTGRCY-------- 448
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
C P ++G +CD CA GF G + P + TR G
Sbjct: 449 ------CRPNFSGERCDV-CAEGFTGFPSCYPTPSSSND----------TREQVLPAGQI 491
Query: 359 CETKCSN-GTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQ 417
CS GT G C D + GRCLC P G HC + C PG +G C Q
Sbjct: 492 VNCDCSAAGTQGNAC----------RKDPRVGRCLCKPNFQGTHCEL-CAPGFYGPGC-Q 539
Query: 418 ACSCH-----EDTCDPVTGAC 433
C C +D CDP TG C
Sbjct: 540 PCQCSSPGVADDRCDPDTGQC 560
Score = 86.3 bits (212), Expect = 1e-16
Identities = 93/342 (27%), Positives = 126/342 (36%), Gaps = 57/342 (16%)
Query: 262 PGYRGKYCREPCPAG--FYGLGCRR-RCGQCKGQQP-CTVAEGRCLTCEPGWNGTKCDQP 317
P +CR + FY G R C + P C G+C C G C +
Sbjct: 1413 PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQC-PCHAHVIGRDCSR- 1470
Query: 318 CATGFYGEGCSHRCPPCRDG-HACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVC 376
CATG++G C PC G C+ +TG+C C I C C T+G C
Sbjct: 1471 CATGYWG---FPNCRPCDCGARLCDELTGQCI-CPPRTIPPDC-LLCQPQTFGCHPLVGC 1525
Query: 377 ADC---GSG-------HCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHE--- 423
+C G G CD SG+C C P V G C+ TC PG HG + C CHE
Sbjct: 1526 EECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCRPCDCHEAGT 1584
Query: 424 --DTCDPVTGACHLETNQRKGVMGAGALLVLLV-------CLLLSLLGCCCACRGKDPTR 474
CDP+TG C+ + N + +L + C G CR TR
Sbjct: 1585 APGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATERCRSSSYTR 1644
Query: 475 RE---------LSLGRKKAPHRLCGRFSRISMKLPRIPLRRQKLPKVVVAHHDLDNTLNC 525
+E LS R+ PH + L +P + +P+ +
Sbjct: 1645 QEFVDMEGWVLLSTDRQVVPHERQPGTEMLRADLRHVP---EAVPEAFPELY-------- 1693
Query: 526 SFLEPPSGLEQPSPSWSSRASFSSFDTTDEGPVYCVPHEEAP 567
+ PPS L S+ + T G V+ VP E P
Sbjct: 1694 -WQAPPSYLGDRVSSYGGTLRYELHSETQRGDVF-VPMESRP 1733
Score = 78.2 bits (191), Expect = 3e-14
Identities = 61/200 (30%), Positives = 79/200 (39%), Gaps = 48/200 (24%)
Query: 193 CDPQTGACLCHA------------GWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARC 240
C+P G C CHA G+WG C C + C++ +G+C C RT C
Sbjct: 1450 CEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDC 1509
Query: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
CQ CHP+ G C C P C GQCK
Sbjct: 1510 -LLCQPQTFGCHPLVGCEECN-------CSGPGIQELTDPTCDTDSGQCK---------- 1551
Query: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGH-------ACNHVTGKCTRCNAG 353
C P G +CD C+ GF+G RC PC D H C+ +TG+C C
Sbjct: 1552 ----CRPNVTGRRCD-TCSPGFHG---YPRCRPC-DCHEAGTAPGVCDPLTGQC-YCKEN 1601
Query: 354 WIGDRCETKCSNGTYGEDCA 373
G +C+ +CS GT+ D A
Sbjct: 1602 VQGPKCD-QCSLGTFSLDAA 1620
Score = 76.6 bits (187), Expect = 9e-14
Identities = 61/223 (27%), Positives = 75/223 (33%), Gaps = 69/223 (30%)
Query: 126 CSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQC 181
C CH G CE GQC CHA G C RC G+WG
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-----------------RCATGYWGFPN 1480
Query: 182 ASACYCSATSRCDPQTGACLCHAGWWGRSC---------------NNQCACN-------- 218
C C A CD TG C+C C +C C+
Sbjct: 1481 CRPCDCGA-RLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELT 1539
Query: 219 SSPCEQQSGRCQCRERTFGARCD------------RYCQCFR-----GRCHPVDGTCACE 261
C+ SG+C+CR G RCD R C C G C P+ G C C+
Sbjct: 1540 DPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCK 1599
Query: 262 PGYRGKYCREPCPAGFYGLGCR--RRCGQCKGQQPCTVAEGRC 302
+G C + C G + L + C +C C A RC
Sbjct: 1600 ENVQGPKC-DQCSLGTFSLDAANPKGCTRCF----CFGATERC 1637
Score = 74.7 bits (182), Expect = 3e-13
Identities = 51/172 (29%), Positives = 71/172 (41%), Gaps = 31/172 (18%)
Query: 96 GECRCRHGYFGANCDTKCPRQFWG-PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEH 154
G+C C G +C ++C +WG P+C+ C C C+++TGQC C R C
Sbjct: 1455 GQCPCHAHVIGRDC-SRCATGYWGFPNCRP-CDCGAR-LCDELTGQCICPPRTIPPDC-L 1510
Query: 155 ACQCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN-- 212
CQ Q CHP G C G Q + CD +G C C GR C+
Sbjct: 1511 LCQPQTFGCHPLVGCEECNCSGPGIQELT------DPTCDTDSGQCKCRPNVTGRRCDTC 1564
Query: 213 ----------NQCACNSS-----PCEQQSGRCQCRERTFGARCDRYCQCFRG 249
C C+ + C+ +G+C C+E G +CD QC G
Sbjct: 1565 SPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD---QCSLG 1613
Score = 53.5 bits (127), Expect = 8e-07
Identities = 34/100 (34%), Positives = 45/100 (45%), Gaps = 14/100 (14%)
Query: 96 GECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQ----CEDVTGQCTCHARRWGAR 151
G+C+CR G CDT P P C+ C CH G C+ +TGQC C G +
Sbjct: 1548 GQCKCRPNVTGRRCDTCSPGFHGYPRCRP-CDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
Query: 152 CEHACQCQHGT-----CHPRSGACRCEPGWWGAQCASACY 186
C+ QC GT +P+ G RC +C S+ Y
Sbjct: 1607 CD---QCSLGTFSLDAANPK-GCTRCFCFGATERCRSSSY 1642
Score = 37.0 bits (84), Expect = 0.079
Identities = 44/167 (26%), Positives = 62/167 (37%), Gaps = 26/167 (15%)
Query: 282 CRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF----YGEGCSHRCPPCRDG 337
C C + P +C TC+ G CD+ C GF + ++ C+
Sbjct: 302 CHGHADACDAKDPTDPFRLQC-TCQHNTCGGTCDR-CCPGFNQQPWKPATANSANECQ-- 357
Query: 338 HACNHVTGKCTRCNAGWIGDRCETKCS-NGTYGEDCAFVCADCGSGHCDFQSGRCLCSPG 396
+CN G T C DR S +GTY VC DC RCL PG
Sbjct: 358 -SCN-CYGHATDCYYDPEVDRRRASQSLDGTY--QGGGVCIDCQHHTTGVNCERCL--PG 411
Query: 397 VH-GPHCNVTCPPGLHGADCAQACSCHED----TCDPVTGACHLETN 438
+ P+ + P + C+C D TC+ +TG C+ N
Sbjct: 412 FYRSPNHPLDSP------HVCRRCNCESDFTDGTCEDLTGRCYCRPN 452
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 137 bits (346), Expect = 3e-32
Identities = 126/422 (29%), Positives = 170/422 (40%), Gaps = 108/422 (25%)
Query: 51 RNVCRAPGSQVP-TCCAGWRQ-----QGDECGIAVCEGNSTCSENEVCVRPGECRCRHGY 104
R +C P S+ TC G GD+C +C N C CV EC C G+
Sbjct: 249 REICPVPCSEEHGTCVDGLCVCHDGFAGDDCNKPLCLNN--CYNRGRCVE-NECVCDEGF 305
Query: 105 FGANCDTK------------------CPRQFWGPDC-KELC--SCHPHGQCEDVTGQCTC 143
G +C C F G DC K C +CH G+CE+ GQC C
Sbjct: 306 TGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCGKPTCPHACHTQGRCEE--GQCVC 363
Query: 144 HARRWGARC-EHACQCQHGTCHPRS----GACRCEPGWWGAQCASACY---CSATSRCDP 195
G C E C CH R G C C+ G+ GA C CS RC
Sbjct: 364 DEGFAGVDCSEKRCPAD---CHNRGRCVDGRCECDDGFTGADCGELKCPNGCSGHGRC-- 418
Query: 196 QTGACLCHAGWWGRSCNNQCACNSSPCEQQS----GRCQCRERTFGARC-DRYC--QCFR 248
G C+C G+ G C+ Q C + C + G+C C + G C D C C +
Sbjct: 419 VNGQCVCDEGYTGEDCS-QLRCPND-CHSRGRCVEGKCVCEQGFKGYDCSDMSCPNDCHQ 476
Query: 249 -GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQ-CKGQQPCTVAEGRCLTCE 306
GRC V+G C C+ GY G+ CR+ R+C + C + C +G+C+ CE
Sbjct: 477 HGRC--VNGMCVCDDGYTGEDCRD------------RQCPRDCSNRGLCV--DGQCV-CE 519
Query: 307 PGWNGTKCDQ-PCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRC-ETKCS 364
G+ G C + C +G+G RC V G+C C+ G++G C E +C
Sbjct: 520 DGFTGPDCAELSCPNDCHGQG---RC-----------VNGQCV-CHEGFMGKDCKEQRCP 564
Query: 365 NGTYGE------DC----AFVCADCGSGHCDFQ--------SGRCLCSPGVHGPHCNVTC 406
+ +G+ C F DCG C SGRC+C+ G G C+
Sbjct: 565 SDCHGQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQCVSGRCICNEGYSGEDCSEVS 624
Query: 407 PP 408
PP
Sbjct: 625 PP 626
Score = 132 bits (332), Expect = 1e-30
Identities = 122/406 (30%), Positives = 154/406 (37%), Gaps = 95/406 (23%)
Query: 98 CRCRHGYFGANCDTKCPRQFWGPDCKE-LC--SCHPHGQCEDVTGQCTCHARRWGARCEH 154
C R + C C + GP+C E C +CH G+C D GQC C G C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCID--GQCICDDGFTGEDCSQ 218
Query: 155 -ACQC---QHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQT---GACLCHAGWW 207
AC G C +G C C G+ GA C S C + T G C+CH G+
Sbjct: 219 LACPSDCNDQGKC--VNGVCICFEGYAGADC-SREICPVPCSEEHGTCVDGLCVCHDGFA 275
Query: 208 GRSCNNQCACNSSPCEQQ----SGRCQCRERTFGARCDRYC---QCF-RGRCHPVDGTCA 259
G CN N+ C + C C E G C CF RGRC ++GTC
Sbjct: 276 GDDCNKPLCLNN--CYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY 331
Query: 260 CEPGYRGKYCREP------------------CPAGFYGLGC-RRRC-GQCKGQQPCTVAE 299
CE G+ G+ C +P C GF G+ C +RC C + C +
Sbjct: 332 CEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRC--VD 389
Query: 300 GRCLTCEPGWNGTKCDQ------------------PCATGFYGEGCSH-RCP-PCRDGHA 339
GRC C+ G+ G C + C G+ GE CS RCP C
Sbjct: 390 GRC-ECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGR 448
Query: 340 CNHVTGKCTRCNAGWIGDRCET-----------KCSNGTYGEDCAFVCADCGSGHCDFQ- 387
C V GKC C G+ G C +C NG D + DC C
Sbjct: 449 C--VEGKCV-CEQGFKGYDCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDC 505
Query: 388 -------SGRCLCSPGVHGPHC-NVTCPPGLHG-ADCAQA-CSCHE 423
G+C+C G GP C ++CP HG C C CHE
Sbjct: 506 SNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRCVNGQCVCHE 551
Score = 107 bits (268), Expect = 4e-23
Identities = 111/368 (30%), Positives = 133/368 (36%), Gaps = 91/368 (24%)
Query: 120 PDCKELCSC--HPHGQCEDVTGQCT----CHARRWGARCEHACQCQ-HGTCHPRSGACRC 172
PD KEL S + QCT C + R + C G C C
Sbjct: 117 PDVKELLSRLEELENLVSSLREQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVC 176
Query: 173 EPGWWGAQCAS-AC--YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQ---- 225
EPGW G C+ C C RC G C+C G+ G C +Q AC S C Q
Sbjct: 177 EPGWKGPNCSEPECPGNCHLRGRC--IDGQCICDDGFTGEDC-SQLAC-PSDCNDQGKCV 232
Query: 226 SGRCQCRERTFGARCDRY-----CQCFRGRCHPVDGTCACEPGYRGKYCREP-------- 272
+G C C E GA C R C G C VDG C C G+ G C +P
Sbjct: 233 NGVCICFEGYAGADCSREICPVPCSEEHGTC--VDGLCVCHDGFAGDDCNKPLCLNNCYN 290
Query: 273 ----------CPAGFYGLGCRRRC--GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP--- 317
C GF G C C + C G C CE G+ G C +P
Sbjct: 291 RGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCY-CEEGFTGEDCGKPTCP 347
Query: 318 ---------------CATGFYGEGCSH-RCP-PCRDGHACNHVTGKCTRCNAGWIGDRC- 359
C GF G CS RCP C + C V G+C C+ G+ G C
Sbjct: 348 HACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRC--VDGRC-ECDDGFTGADCG 404
Query: 360 ETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN-VTCPPGLHGADCAQA 418
E KC NG SGH +G+C+C G G C+ + CP DC
Sbjct: 405 ELKCPNGC-------------SGHGRCVNGQCVCDEGYTGEDCSQLRCP-----NDCHSR 446
Query: 419 CSCHEDTC 426
C E C
Sbjct: 447 GRCVEGKC 454
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 130 bits (326), Expect = 7e-30
Identities = 121/439 (27%), Positives = 160/439 (36%), Gaps = 115/439 (26%)
Query: 74 ECGIAVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTKCPRQF-WGPDCKELCSCHPH 131
+ G+A CE + S + VC G+C+CR G C+ P F +GP + C CH
Sbjct: 768 QTGLA-CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQ 826
Query: 132 GQ----CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYC 187
G C VTGQC C + +C+ RC PG WG C C
Sbjct: 827 GSVNAFCNPVTGQCHCFQGVYARQCD-----------------RCLPGHWGFPSCQPCQC 869
Query: 188 SA-TSRCDPQTGACL-CHAGWWGRSCNNQCA-------------CNSSPCEQ--QSGR-- 228
+ CDP TG CL C G +C A C PC SGR
Sbjct: 870 NGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQF 929
Query: 229 --------------CQCRERTFGARCD-----------------RYCQCFRG-------R 250
C C G+RCD + CQC
Sbjct: 930 ARSCYQDPVTLQLACVCDPGYIGSRCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEA 989
Query: 251 CHPVDGTCA-CEPGYRGKYCREPCPAGFYGLGCRRRCGQCK-------------GQQPCT 296
C G C C G++C+ C G+YG ++ C +C C
Sbjct: 990 CDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCD 1048
Query: 297 VAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRD------GHACNHVTGKCTRC 350
A G+CL C P G CD+ CA + C PC G +CN TG+C +C
Sbjct: 1049 KATGQCL-CLPNVIGQNCDR-CAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQC-QC 1105
Query: 351 NAGWIGDRCETKCSNGTYGE-DCAFVCADCG-----SGHCDFQSGRCLCSPGVHGPHCNV 404
G+ G C ++C +G+ D DC + CD +G+C+C GV GP C+
Sbjct: 1106 MPGFGGRTC-SECQELFWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD- 1163
Query: 405 TCPPGLHGA--DCAQACSC 421
C G G DC C
Sbjct: 1164 KCTRGYSGVFPDCTPCHQC 1182
Score = 121 bits (303), Expect = 3e-27
Identities = 101/361 (27%), Positives = 144/361 (39%), Gaps = 83/361 (22%)
Query: 126 CSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQC 181
C C P G C+ GQC C G C +C GT G C+P C
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN---RCAPGTFG--FGPSGCKP------C 821
Query: 182 ASACYCSATSRCDPQTGACLCHAGWWGRSCNN------------QCACN--SSPCEQQSG 227
S + C+P TG C C G + R C+ C CN + C+ +G
Sbjct: 822 ECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTG 881
Query: 228 RC-QCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCRE-PCPAGFYGLGCRRR 285
C C++ T G C+R + G P+ G+ G +CR PCP G R+
Sbjct: 882 ECLNCQDYTMGHNCERCLAGYYG--DPIIGS--------GDHCRPCPCPDG---PDSGRQ 928
Query: 286 CGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCS--HRCPPCR-------- 335
+ Q P T+ C+PG+ G++CD CA+G++G C PC+
Sbjct: 929 FARSCYQDPVTLQ--LACVCDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTT 985
Query: 336 DGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH------------ 383
D AC+ TG+C +C G+ C+ C G YG+ C C +
Sbjct: 986 DPEACDKETGRCLKCLYHTEGEHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSD 1044
Query: 384 --CDFQSGRCLCSPGVHGPHCNVTCPPG----LHGADCAQACSCHE-----DTCDPVTGA 432
CD +G+CLC P V G +C+ C P G C C+C+ +C+ TG
Sbjct: 1045 CQCDKATGQCLCLPNVIGQNCD-RCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQ 1102
Query: 433 C 433
C
Sbjct: 1103 C 1103
Score = 61.6 bits (148), Expect = 3e-09
Identities = 65/269 (24%), Positives = 86/269 (31%), Gaps = 102/269 (37%)
Query: 96 GECRCRHGYFGANCDTKCPRQF----WGPD-------CKELCSCHPH------------- 131
G C CRH G NC+ C + W P CK+ C+C+ H
Sbjct: 296 GHCMCRHNTKGLNCEL-CMDFYHDLPWRPAEGRNSNACKK-CNCNEHSISCHFDMAVYLA 353
Query: 132 ------GQCEDVTGQCTCHARRWGARCEHACQ----------------CQHGTCHP---- 165
G C+D C G CE C+ C+ TC P
Sbjct: 354 TGNVSGGVCDD------CQHNTMGRNCEQ-CKPFYYQHPERDIRDPNFCERCTCDPAGSQ 406
Query: 166 RSGACRCEPGWWGAQCASACYCSAT---SRCDPQTGACLCHAGWWGRSCNN-----QCAC 217
G C + A C C CD +C G++ S + CAC
Sbjct: 407 NEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD------VCKEGFYDLSSEDPFGCKSCAC 460
Query: 218 N-------SSPCEQQSGRCQCRERTFGARCD----------------RYCQCFRG----- 249
N +PC+ ++G C C+ G CD R C C G
Sbjct: 461 NPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNN 520
Query: 250 RCHPVDGTCACEPGYRGKYCREPCPAGFY 278
C G C+C P G+ C E P G+Y
Sbjct: 521 SCFAESGQCSCRPHMIGRQCNEVEP-GYY 548
Score = 55.5 bits (132), Expect = 2e-07
Identities = 36/111 (32%), Positives = 46/111 (41%), Gaps = 11/111 (9%)
Query: 58 GSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQ 116
G C Q G C N+ S C G+C+C G+ G C ++C
Sbjct: 1062 GQNCDRCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC-SECQEL 1120
Query: 117 FWG-PDCK-ELCSCHPHG----QCEDVTGQCTCHARRWGARCEHACQCQHG 161
FWG PD + C C P G QC+ TGQC C G RC+ +C G
Sbjct: 1121 FWGDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD---KCTRG 1168
Score = 50.4 bits (119), Expect = 7e-06
Identities = 66/280 (23%), Positives = 90/280 (32%), Gaps = 58/280 (20%)
Query: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
G C C+ C N G C CR T G C+ C F H +
Sbjct: 269 GNCFCYGH--ASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE-LCMDFY---HDLPWR 322
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
A G C++ C + + C V+ G C C+ G C+Q
Sbjct: 323 PA--EGRNSNACKK-CNCNEHSISCHFDMAVYLATG--NVSGGVCDDCQHNTMGRNCEQ- 376
Query: 318 CATGFYGEGCSHRCPPCRDGHACNHVT------------------------GKCTRCNAG 353
C +Y H RD + C T G+C RC
Sbjct: 377 CKPFYY----QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC-RCKLN 431
Query: 354 WIGDRCETKCSNGTY--GEDCAFVCADC---------GSGHCDFQSGRCLCSPGVHGPHC 402
G+ C+ C G Y + F C C G CD ++G C C V G HC
Sbjct: 432 VEGEHCDV-CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHC 490
Query: 403 NVTCPP--GL-HGADCAQACSCHEDTCDPVTGACHLETNQ 439
+ P GL + D + C C D + +C E+ Q
Sbjct: 491 DQCLPEHWGLSNDLDGCRPCDC--DLGGALNNSCFAESGQ 528
Score = 46.2 bits (108), Expect = 1e-04
Identities = 26/62 (41%), Positives = 30/62 (48%), Gaps = 10/62 (16%)
Query: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHG---ADCAQACSCH-----EDTCDPVTGA 432
S CD G+C C P V G CN C PG G + C + C CH C+PVTG
Sbjct: 782 SSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGC-KPCECHLQGSVNAFCNPVTGQ 839
Query: 433 CH 434
CH
Sbjct: 840 CH 841
Score = 43.9 bits (102), Expect = 6e-04
Identities = 80/307 (26%), Positives = 103/307 (33%), Gaps = 64/307 (20%)
Query: 137 VTGQCTCHARRWGARCEHACQCQ---------HGTCHPRSGACRCEPGWWGAQCASACYC 187
V G C C+ HA +C G H G C C G C
Sbjct: 267 VRGNCFCYG--------HASECAPVDGFNEEVEGMVH---GHCMCRHNTKGLNCELCMDF 315
Query: 188 SATSRCDPQTG----ACL-CHAGWWGRSCNNQCACNSSPCEQQSGRCQ-CRERTFGARCD 241
P G AC C+ SC+ A + G C C+ T G C+
Sbjct: 316 YHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCE 375
Query: 242 RYCQCFRGRCHPVDGTCACEPGYRGKYCREPC---PAGFYGLGCRRRCGQCKGQQPCTVA 298
+ C+ F + HP E R E C PAG G C +A
Sbjct: 376 Q-CKPFYYQ-HP-------ERDIRDPNFCERCTCDPAGSQNEGI---CDSYTDFSTGLIA 423
Query: 299 EGRCLTCEPGWNGTKCDQPCATGFYGE------GC-SHRCPPCRD---GHACNHVTGKCT 348
G+C C+ G CD C GFY GC S C P G+ C+ TG C
Sbjct: 424 -GQC-RCKLNVEGEHCDV-CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCY 480
Query: 349 RCNAGWIGDRCETKCSNGTYG-----EDCAFVCADCG---SGHCDFQSGRCLCSPGVHGP 400
C G C+ +C +G + C D G + C +SG+C C P + G
Sbjct: 481 -CKRLVTGQHCD-QCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGR 538
Query: 401 HCNVTCP 407
CN P
Sbjct: 539 QCNEVEP 545
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 129 bits (325), Expect = 9e-30
Identities = 125/463 (26%), Positives = 163/463 (35%), Gaps = 138/463 (29%)
Query: 98 CRCRHGYFGANCDTKCPRQ------FWGPDCKELCSCHPHGQ-CEDVTGQC-TCHARRWG 149
C+C GY G++C++ PR +G C E C C H + C+DVTG+C C G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 150 ARCEHA------------------CQCQHG--------TCH------------------P 165
C+ C C TCH P
Sbjct: 783 PYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 166 RSGACRCEPGWWG-----------AQCASACYCSATSRCDPQTGACL-CHAGWWGRSCN- 212
R RC G++G QC S CD +G+CL C G GR C
Sbjct: 843 RCE--RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 213 ---------------NQCACN-----SSPCEQQSGRCQCRERTFGARCDRY------CQC 246
C CN S C Q+G+C+CR G RCD+ Q
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS 960
Query: 247 FRGRCHPVD--------------GTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQC 289
RG C P + G C C+PG GK C + C G++ GC C
Sbjct: 961 ARG-CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECS 1017
Query: 290 KGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDG------HACNHV 343
C GRC+ C P G KC + CA +G + C C CN
Sbjct: 1018 HLGNNCDPKTGRCI-CPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVN 1075
Query: 344 TGKCTRCNAGWIGDRCETKCSNGTY-------------GEDCAFVCADCGSGHCDFQSGR 390
TG+C C+ + G +C T+CS G + G D ++ C Q+G+
Sbjct: 1076 TGQC-NCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 391 CLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGAC 433
C C V G HC+ C PG G D C C T C
Sbjct: 1134 CTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSSCYCFGTTTQC 1175
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/259 (25%), Positives = 92/259 (35%), Gaps = 39/259 (15%)
Query: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
G C+C+ R+C A N S RC+C T G CD+ C F + GT
Sbjct: 285 GMCICYGH--ARACPLDPATNKS-------RCECEHNTCGDSCDQCCPGFHQKPWRA-GT 334
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCRRR--CGQCKGQQPCTVAEGRCLTCEPGWNGTKCD 315
+ C +Y RR +G+ + G C+ C G C
Sbjct: 335 FLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKY---IGGGVCINCTQNTAGINC- 390
Query: 316 QPCATGFY-GEGCS----HRCPPCR--------------DGHACNHVTGKCTRCNAGWIG 356
+ C GF+ +G S C PC + HA + C G+ G
Sbjct: 391 ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGG 450
Query: 357 DRCETKCSNGTYG-EDC-AFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
C+ +C+ G G DC A C+ GS + D G C+C V G C+ C G
Sbjct: 451 VSCD-RCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFNLQ 508
Query: 415 CAQACSCHEDTCDPVTGAC 433
C E C V+ C
Sbjct: 509 EDNWKGCDECFCSGVSNRC 527
Score = 56.2 bits (134), Expect = 1e-07
Identities = 64/238 (26%), Positives = 83/238 (34%), Gaps = 66/238 (27%)
Query: 52 NVCRAPGSQVPTCCAGWRQQG---------DECGIAVCEGNST-CSENEVCVRP------ 95
N C G CC G+ Q+ EC C G + C +E R
Sbjct: 312 NTC---GDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNI 368
Query: 96 -------GEC-RCRHGYFGANCDTKCPRQFWGPD---------CKELCSCHPHGQCEDVT 138
G C C G NC+T C F+ P C+ C C P G +V
Sbjct: 369 RGKYIGGGVCINCTQNTAGINCET-CTDGFFRPKGVSPNYPRPCQP-CHCDPIGSLNEVC 426
Query: 139 GQCTCHARRWGARCEHACQCQHGTCHPRSG----AC-RCEPGWWGAQCASACYCSA--TS 191
+ HARR A G+CH ++G +C RC G+ G AC CS +
Sbjct: 427 VKDEKHARRGLAP---------GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSK 477
Query: 192 RCDPQTGACLCHAGWWGRSCN------------NQCACNSSPCEQQSGRCQCRERTFG 237
DP G C+C G C+ N C+ C S RCQ T+G
Sbjct: 478 NEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYG 535
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 47/186 (25%)
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCR---RRCG---------QCKGQQP-CTVAEGRCLT 304
C C GY G C E C GFY L + R G QC G C C
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 305 CEPGWNGTKCDQPCATGFYG--EGCSHRCPPCRDGHACNHVTG----------------K 346
C+ G C++ CA G+YG +G + C C AC ++ +
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQC----ACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 347 CTRCNAGWIGDRCETKCSNGTYGE--DCAFVCADCGSGH-------CDFQSGRCLCSPGV 397
CT C G+ G CE +C+ G G + C +C CD +G C C PG
Sbjct: 1494 CTACPRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 398 HGPHCN 403
G C+
Sbjct: 1553 TGRKCD 1558
Score = 51.2 bits (121), Expect = 4e-06
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 42/168 (25%)
Query: 305 CEPGWNGTKCDQPCATGFYGEGCSH----------RCPPCR-DGHA--CNHVTGKCTRCN 351
C G++G C+ C GFY C PC+ +GH+ C+ T C C
Sbjct: 1382 CPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 352 AGWIGDRCETKCSNGTYG------EDCAFVCADCGSGHCDFQSG---------RCLCSP- 395
GD CE +C+ G YG DC S +F RC P
Sbjct: 1441 HHTAGDFCE-RCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPR 1499
Query: 396 GVHGPHCNVTCPPGLHGADCAQACSCHE----------DTCDPVTGAC 433
G G +C C PG G+ SC E CDPVTG C
Sbjct: 1500 GYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 31/165 (18%)
Query: 67 GWRQQGDECGIAV---CEGNSTCSENEVCVRPGECR-CRHGYFGANCDTKCPRQFWG--- 119
G R G G V C G+S+ + E + C+ C+H G C+ +C ++G
Sbjct: 1406 GGRTPGPTLGTCVPCQCNGHSSLCDPETSI----CQNCQHHTAGDFCE-RCALGYYGIVK 1460
Query: 120 ---PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGW 176
DC++ C+C + + C G C G + RC PG+
Sbjct: 1461 GLPNDCQQ-CACPLISSSNNFSPSCVAE----GLDDYRCTACPRG--YEGQYCERCAPGY 1513
Query: 177 WGA---------QCASACYCSATSRCDPQTGACLCHAGWWGRSCN 212
G+ +C Y S CDP TG C C G GR C+
Sbjct: 1514 TGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 45.4 bits (106), Expect = 2e-04
Identities = 50/196 (25%), Positives = 67/196 (34%), Gaps = 40/196 (20%)
Query: 97 ECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT-GQCT-CHARRWGARCE- 153
+C C GY G +C+ P + P G+ T G C C + C+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFY-------RLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 154 --HACQ-CQHGTCHPRSGAC-RCEPGWWGA-----QCASACYCSATSRCDPQTGACL--- 201
CQ CQH H C RC G++G C C S + + +C+
Sbjct: 1432 ETSICQNCQH---HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEG 1488
Query: 202 --------CHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHP 253
C G+ G+ C + G CQ E CD Y C P
Sbjct: 1489 LDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECE------CDPYGS-LPVPCDP 1541
Query: 254 VDGTCACEPGYRGKYC 269
V G C C PG G+ C
Sbjct: 1542 VTGFCTCRPGATGRKC 1557
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 129 bits (325), Expect = 9e-30
Identities = 125/463 (26%), Positives = 163/463 (35%), Gaps = 138/463 (29%)
Query: 98 CRCRHGYFGANCDTKCPRQ------FWGPDCKELCSCHPHGQ-CEDVTGQC-TCHARRWG 149
C+C GY G++C++ PR +G C E C C H + C+DVTG+C C G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 150 ARCEHA------------------CQCQHG--------TCH------------------P 165
C+ C C TCH P
Sbjct: 783 PYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 166 RSGACRCEPGWWG-----------AQCASACYCSATSRCDPQTGACL-CHAGWWGRSCN- 212
R RC G++G QC S CD +G+CL C G GR C
Sbjct: 843 RCE--RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL 900
Query: 213 ---------------NQCACN-----SSPCEQQSGRCQCRERTFGARCDRY------CQC 246
C CN S C Q+G+C+CR G RCD+ Q
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQS 960
Query: 247 FRGRCHPVD--------------GTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQC 289
RG C P + G C C+PG GK C + C G++ GC C
Sbjct: 961 ARG-CVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGC-TACECS 1017
Query: 290 KGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDG------HACNHV 343
C GRC+ C P G KC + CA +G + C C CN
Sbjct: 1018 HLGNNCDPKTGRCI-CPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVN 1075
Query: 344 TGKCTRCNAGWIGDRCETKCSNGTY-------------GEDCAFVCADCGSGHCDFQSGR 390
TG+C C+ + G +C T+CS G + G D ++ C Q+G+
Sbjct: 1076 TGQC-NCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQ 1133
Query: 391 CLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGAC 433
C C V G HC+ C PG G D C C T C
Sbjct: 1134 CTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSSCYCFGTTTQC 1175
Score = 62.0 bits (149), Expect = 2e-09
Identities = 66/259 (25%), Positives = 92/259 (35%), Gaps = 39/259 (15%)
Query: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
G C+C+ R+C A N S RC+C T G CD+ C F + GT
Sbjct: 285 GMCICYGH--ARACPLDPATNKS-------RCECEHNTCGDSCDQCCPGFHQKPWRA-GT 334
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCRRR--CGQCKGQQPCTVAEGRCLTCEPGWNGTKCD 315
+ C +Y RR +G+ + G C+ C G C
Sbjct: 335 FLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKY---IGGGVCINCTQNTAGINC- 390
Query: 316 QPCATGFY-GEGCS----HRCPPCR--------------DGHACNHVTGKCTRCNAGWIG 356
+ C GF+ +G S C PC + HA + C G+ G
Sbjct: 391 ETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGG 450
Query: 357 DRCETKCSNGTYG-EDC-AFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
C+ +C+ G G DC A C+ GS + D G C+C V G C+ C G
Sbjct: 451 VSCD-RCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFNLQ 508
Query: 415 CAQACSCHEDTCDPVTGAC 433
C E C V+ C
Sbjct: 509 EDNWKGCDECFCSGVSNRC 527
Score = 56.2 bits (134), Expect = 1e-07
Identities = 64/238 (26%), Positives = 83/238 (34%), Gaps = 66/238 (27%)
Query: 52 NVCRAPGSQVPTCCAGWRQQG---------DECGIAVCEGNST-CSENEVCVRP------ 95
N C G CC G+ Q+ EC C G + C +E R
Sbjct: 312 NTC---GDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNI 368
Query: 96 -------GEC-RCRHGYFGANCDTKCPRQFWGPD---------CKELCSCHPHGQCEDVT 138
G C C G NC+T C F+ P C+ C C P G +V
Sbjct: 369 RGKYIGGGVCINCTQNTAGINCET-CTDGFFRPKGVSPNYPRPCQP-CHCDPIGSLNEVC 426
Query: 139 GQCTCHARRWGARCEHACQCQHGTCHPRSG----AC-RCEPGWWGAQCASACYCSA--TS 191
+ HARR A G+CH ++G +C RC G+ G AC CS +
Sbjct: 427 VKDEKHARRGLAP---------GSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSK 477
Query: 192 RCDPQTGACLCHAGWWGRSCN------------NQCACNSSPCEQQSGRCQCRERTFG 237
DP G C+C G C+ N C+ C S RCQ T+G
Sbjct: 478 NEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECFCSGVSNRCQSSYWTYG 535
Score = 55.8 bits (133), Expect = 2e-07
Identities = 53/186 (28%), Positives = 70/186 (37%), Gaps = 47/186 (25%)
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCR---RRCG---------QCKGQQP-CTVAEGRCLT 304
C C GY G C E C GFY L + R G QC G C C
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 305 CEPGWNGTKCDQPCATGFYG--EGCSHRCPPCRDGHACNHVTG----------------K 346
C+ G C++ CA G+YG +G + C C AC ++ +
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQC----ACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 347 CTRCNAGWIGDRCETKCSNGTYGE--DCAFVCADCGSGH-------CDFQSGRCLCSPGV 397
CT C G+ G CE +C+ G G + C +C CD +G C C PG
Sbjct: 1494 CTACPRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGA 1552
Query: 398 HGPHCN 403
G C+
Sbjct: 1553 TGRKCD 1558
Score = 51.2 bits (121), Expect = 4e-06
Identities = 49/168 (29%), Positives = 61/168 (36%), Gaps = 42/168 (25%)
Query: 305 CEPGWNGTKCDQPCATGFYGEGCSH----------RCPPCR-DGHA--CNHVTGKCTRCN 351
C G++G C+ C GFY C PC+ +GH+ C+ T C C
Sbjct: 1382 CPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNCQ 1440
Query: 352 AGWIGDRCETKCSNGTYG------EDCAFVCADCGSGHCDFQSG---------RCLCSP- 395
GD CE +C+ G YG DC S +F RC P
Sbjct: 1441 HHTAGDFCE-RCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPR 1499
Query: 396 GVHGPHCNVTCPPGLHGADCAQACSCHE----------DTCDPVTGAC 433
G G +C C PG G+ SC E CDPVTG C
Sbjct: 1500 GYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFC 1546
Score = 46.2 bits (108), Expect = 1e-04
Identities = 43/165 (26%), Positives = 63/165 (38%), Gaps = 31/165 (18%)
Query: 67 GWRQQGDECGIAV---CEGNSTCSENEVCVRPGECR-CRHGYFGANCDTKCPRQFWG--- 119
G R G G V C G+S+ + E + C+ C+H G C+ +C ++G
Sbjct: 1406 GGRTPGPTLGTCVPCQCNGHSSLCDPETSI----CQNCQHHTAGDFCE-RCALGYYGIVK 1460
Query: 120 ---PDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGW 176
DC++ C+C + + C G C G + RC PG+
Sbjct: 1461 GLPNDCQQ-CACPLISSSNNFSPSCVAE----GLDDYRCTACPRG--YEGQYCERCAPGY 1513
Query: 177 WGA---------QCASACYCSATSRCDPQTGACLCHAGWWGRSCN 212
G+ +C Y S CDP TG C C G GR C+
Sbjct: 1514 TGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 45.4 bits (106), Expect = 2e-04
Identities = 50/196 (25%), Positives = 67/196 (34%), Gaps = 40/196 (20%)
Query: 97 ECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVT-GQCT-CHARRWGARCE- 153
+C C GY G +C+ P + P G+ T G C C + C+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFY-------RLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDP 1431
Query: 154 --HACQ-CQHGTCHPRSGAC-RCEPGWWGA-----QCASACYCSATSRCDPQTGACL--- 201
CQ CQH H C RC G++G C C S + + +C+
Sbjct: 1432 ETSICQNCQH---HTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEG 1488
Query: 202 --------CHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHP 253
C G+ G+ C + G CQ E CD Y C P
Sbjct: 1489 LDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECE------CDPYGS-LPVPCDP 1541
Query: 254 VDGTCACEPGYRGKYC 269
V G C C PG G+ C
Sbjct: 1542 VTGFCTCRPGATGRKC 1557
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 129 bits (324), Expect = 1e-29
Identities = 119/435 (27%), Positives = 156/435 (35%), Gaps = 109/435 (25%)
Query: 76 GIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFW--GPDCKELCSCHPHG 132
G C+ + S C R G+C+C+ G CD +C + G C CHP G
Sbjct: 765 GAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCD-RCSTGSYDLGHHGCHPCHCHPQG 823
Query: 133 Q----CEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCS 188
C+ VTGQC CH G RC+ RC G++G C C+
Sbjct: 824 SKDTVCDQVTGQCPCHGEVSGRRCD-----------------RCLAGYFGFPSCHPCPCN 866
Query: 189 ATSR-CDPQTGACL-------------CHAGWWGRSCNNQ----CACNSSPCEQQSGRCQ 230
+ CDP+TG+C C G++G + Q C C P Q
Sbjct: 867 RFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHS 926
Query: 231 CRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYG----LGCRRRC 286
C + + + D C C GY G C E C GFYG G +
Sbjct: 927 CYQNLWSS----------------DVICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQP 969
Query: 287 GQCKGQ------QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEG-------CS----- 328
C + C+ G CL C G C Q C G YG CS
Sbjct: 970 CACNNNIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGHYGSALNQTCRRCSCHASG 1028
Query: 329 ---HRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCG----- 380
CPP C+ VTG C C G C+ +C++G + C C
Sbjct: 1029 VSPMECPPGGGACLCDPVTGACP-CLPNVTGLACD-RCADGYWNLVPGRGCQSCDCDPRT 1086
Query: 381 --SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHG--------ADCAQACSCHEDTCDPVT 430
S HCD +G+C C G G C+ C +G DC +A + CDP T
Sbjct: 1087 SQSSHCDQLTGQCPCKLGYGGKRCS-ECQENYYGDPPGRCIPCDCNRA-GTQKPICDPDT 1144
Query: 431 GACHLETNQRKGVMG 445
G C R+GV G
Sbjct: 1145 GMCRC----REGVSG 1155
Score = 91.7 bits (226), Expect = 3e-18
Identities = 74/241 (30%), Positives = 91/241 (37%), Gaps = 71/241 (29%)
Query: 58 GSQVPTCCAGW----RQQGDECGIAVCEGNSTCSENEVCVR-PGEC-RCRHGYFGANCDT 111
G+Q C G+ R G C C N ++ E C R GEC RC H GANC
Sbjct: 946 GTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL 1005
Query: 112 KCPRQFWGP---DCKELCSCHPHGQ-------------CEDVTGQCTCHARRWGARCEHA 155
P + C+ CSCH G C+ VTG C C G C+
Sbjct: 1006 CKPGHYGSALNQTCRR-CSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD-- 1062
Query: 156 CQCQHGTCHPRSGACRCEPGWW----GAQCASACYC----SATSRCDPQTGACLCHAGWW 207
RC G+W G C S C C S +S CD TG C C G+
Sbjct: 1063 ---------------RCADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYG 1106
Query: 208 GRSCNN--------------QCACNSSP-----CEQQSGRCQCRERTFGARCDRYCQCFR 248
G+ C+ C CN + C+ +G C+CRE G RCDR C R
Sbjct: 1107 GKRCSECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR---CAR 1163
Query: 249 G 249
G
Sbjct: 1164 G 1164
Score = 67.0 bits (162), Expect = 7e-11
Identities = 84/331 (25%), Positives = 117/331 (35%), Gaps = 101/331 (30%)
Query: 96 GECRCRHGYFGANCDTKCPRQF----WGPD-------CKELCSCHPHG-QCEDVTGQCTC 143
G+C C+H G NC+ +C F W P C+ CSC+ H +C
Sbjct: 293 GQCVCQHNTDGPNCE-RCKDFFQDAPWRPAADLQDNACRS-CSCNSHSSRCHFDMTTYLA 350
Query: 144 HARRWGARCEHACQCQHGTCHPRSGAC-RCEPGWWG--AQCASACYCSATSRCDPQTGAC 200
G CE CQH T C RC P ++ + S Y CDP
Sbjct: 351 SGGLSGGVCE---DCQHNT---EGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD---- 400
Query: 201 LCHAGWWGRSCNNQCACNSSPC-EQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCA 259
G C +S P +G+C C+E GA+CD+
Sbjct: 401 -------GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ----------------- 436
Query: 260 CEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQP---CTVAEGRCLTCEPGWNGTKCDQ 316
C+P + G +P LGC+ G P C V G+CL C G C++
Sbjct: 437 CKPNHYGLSATDP-------LGCQPCDCNPLGSLPFLTCDVDTGQCL-CLSYVTGAHCEE 488
Query: 317 PCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVC 376
C G++G G NH+ G C+ C+ C+ G Y
Sbjct: 489 -CTVGYWGLG--------------NHLHG-CSPCD-------CDI---GGAY-------- 514
Query: 377 ADCGSGHCDFQSGRCLCSPGVHGPHCNVTCP 407
S C ++G+C C P V G C+ P
Sbjct: 515 ----SNVCSPKNGQCECRPHVTGRSCSEPAP 541
Score = 52.8 bits (125), Expect = 1e-06
Identities = 67/262 (25%), Positives = 84/262 (32%), Gaps = 70/262 (26%)
Query: 220 SPCEQQSGRCQCRERTFGARCDRY------------------------CQCFRGRCHPVD 255
SP G+C C+ T G C+R C RCH
Sbjct: 286 SPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDM 345
Query: 256 GTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPC-TVAEG-RCLTCEPGWNGTK 313
T G G C E C G C R C + P T+++ C+ CE +GT
Sbjct: 346 TTYLASGGLSGGVC-EDCQHNTEGQHCDR-CRPLFYRDPLKTISDPYACIPCECDPDGTI 403
Query: 314 CDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA 373
C SH P A V G+C C G +C+ +C YG
Sbjct: 404 SGGICV--------SHSDP------ALGSVAGQCL-CKENVEGAKCD-QCKPNHYGLSAT 447
Query: 374 --FVCADCGSGH--------CDFQSGRCLCSPGVHGPHCNVTCPPG-------LHGADCA 416
C C CD +G+CLC V G HC C G LHG
Sbjct: 448 DPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHG---C 503
Query: 417 QACSC-----HEDTCDPVTGAC 433
C C + + C P G C
Sbjct: 504 SPCDCDIGGAYSNVCSPKNGQC 525
Score = 30.4 bits (67), Expect = 7.4
Identities = 17/65 (26%), Positives = 29/65 (44%), Gaps = 2/65 (3%)
Query: 58 GSQVPTCCAGWRQQGDEC-GIAVCEGNSTCSENEVCV-RPGECRCRHGYFGANCDTKCPR 115
G+ C G+ G+ G + C+ + + + VC + G+C CR G +C P
Sbjct: 483 GAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPG 542
Query: 116 QFWGP 120
F+ P
Sbjct: 543 YFFAP 547
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 127 bits (319), Expect = 4e-29
Identities = 146/552 (26%), Positives = 190/552 (34%), Gaps = 181/552 (32%)
Query: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANC 109
G C G++ C GW G EC AVC+ C PGECRC +G+ G C
Sbjct: 219 GHYTCDQYGNKA--CMDGW--MGKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFC 273
Query: 110 DTKCPR---------QFWGPDC----------KELCSCHPHGQC---------EDVTGQC 141
D P + W +C K+L C H C E +C
Sbjct: 274 DECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRC 333
Query: 142 TCHARRWGARC---EHACQ----CQHGTCH--PRSGACRCEPGWWGAQCA------SACY 186
TC G C EHAC G+CH P C C GW G CA ++
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNP 393
Query: 187 CSATSRCDPQTGA--CLCHAGWWGRSCN---NQC-------------------------- 215
C+A C Q C+C W G +C N C
Sbjct: 394 CAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFG 453
Query: 216 ---------ACNSSPCEQ--------QSGRCQCRERTFGARCD---RYCQ---CFRG-RC 251
C SSPC C C + G C+ C+ C G RC
Sbjct: 454 GRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARC 513
Query: 252 HPVDGT--CACEPGYRGKYC---REPCPAGFYGLGCR--RRCGQCKGQ-QPCTVAEGRCL 303
+ ++G CAC + GK C REPCP G CR CG G P T A G C
Sbjct: 514 YNLEGDYYCACPDDFGGKNCSVPREPCPGG----ACRVIDGCGSDAGPGMPGTAASGVC- 568
Query: 304 TCEPGWNGTKCDQP-------CATGFYGEGCSHRC-----PPCRDGHAC-NHVTGKCTRC 350
G +G QP C +GF G C PCR+G C + V C
Sbjct: 569 ----GPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC 624
Query: 351 NAGWIGDRCETK-------------------------CSNGTYGEDC--------AFVCA 377
+GW G+ C+T C +G G+ C A+ C+
Sbjct: 625 PSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCS 684
Query: 378 DCGSGHCDFQSGRCLCSPGVHGPHC----NVTCPPG--LHGADC-----AQACSCHED-- 424
+ G+ + + RC C PG G C N +C P ++G C + +C C +
Sbjct: 685 NGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWE 744
Query: 425 --TCDPVTGACH 434
TC T C+
Sbjct: 745 GRTCTHNTNDCN 756
Score = 112 bits (281), Expect = 1e-24
Identities = 136/476 (28%), Positives = 161/476 (33%), Gaps = 149/476 (31%)
Query: 54 CRAP-GSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTK 112
C P G PTC DEC C TC + V EC C + GA C
Sbjct: 371 CHCPSGWSGPTCALDI----DECASNPCAAGGTCVDQ---VDGFECICPEQWVGATCQLD 423
Query: 113 ------------------------CPRQFWGPDC---KELCS---CHPHGQCEDVTGQCT 142
CPR F G C ++ C+ CH G CED+
Sbjct: 424 VNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 483
Query: 143 CHAR--------------------RWGARC-----EHACQCQHG----TCH-PRS----G 168
CH R GARC ++ C C C PR G
Sbjct: 484 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG 543
Query: 169 ACR--------CEPGWWGAQCASACYCSATSRCDPQTG---ACLCHAGWWGRSCN-NQCA 216
ACR PG G A++ C RC Q G +C+C +G+ G C+ N
Sbjct: 544 ACRVIDGCGSDAGPGMPGT--AASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDD 601
Query: 217 CNSSPC--------EQQSGRCQCRERTFGARCDRYCQ-CF------RGRCHPV--DGTCA 259
C PC E + RC C G CD C RGRC+ + D CA
Sbjct: 602 CLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCA 661
Query: 260 CEPGYRGKYCRE---PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKC-- 314
C+ G++GK C C A G G C RC C PGW G+ C
Sbjct: 662 CDDGWKGKTCHSREFQCDAYTCSNG-----GTCYDSGDTF----RC-ACPPGWKGSTCAV 711
Query: 315 -------DQPCATG--FYGEGCSHRCPPCRDG---HACNHVTGKCTRC---NAGWIGD-- 357
PC G G G S C CRDG C H T C N G D
Sbjct: 712 AKNSSCLPNPCVNGGTCVGSGASFSCI-CRDGWEGRTCTHNTNDCNPLPCYNGGICVDGV 770
Query: 358 ---RCETKCSNGTYGEDCAFVCADCGSGHC--------DFQSGRCLCSPGVHGPHC 402
RCE C+ G G DC +C S C + RC C PG GP C
Sbjct: 771 NWFRCE--CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRC 824
Score = 96.3 bits (238), Expect = 1e-19
Identities = 100/385 (25%), Positives = 131/385 (34%), Gaps = 107/385 (27%)
Query: 37 LPDTVAPQELNPRGRNVCRAPGSQVPTCCAGW-----RQQGDECGIAVCEGNSTCSENEV 91
+P T A P GR V + G+ C +G+ + D+C C TC +
Sbjct: 559 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD 618
Query: 92 CVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQC---------- 141
R C C G+ G CDT DC CH G+C D+
Sbjct: 619 AFR---CFCPSGWEGELCDTN------PNDCLP-DPCHSRGRCYDLVNDFYCACDDGWKG 668
Query: 142 -TCHARRWGARCEHACQCQHGTCHPRSGA--CRCEPGWWGAQCASA---------CYCSA 189
TCH+R + +C+ GTC+ C C PGW G+ CA A C
Sbjct: 669 KTCHSREF--QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 726
Query: 190 TSRCDPQTGACLCHAGWWGRSC-NNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFR 248
T + +C+C GW GR+C +N CN PC G C
Sbjct: 727 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC-YNGGIC------------------- 766
Query: 249 GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPG 308
VDG + R C GF G CR +C+ PC TC
Sbjct: 767 -----VDGV---------NWFRCECAPGFAGPDCRINIDECQ-SSPCAYG----ATCVDE 807
Query: 309 WNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRC---------NAGWIGDRC 359
NG +C CPP R G C V G C + W+ D
Sbjct: 808 INGYRCS---------------CPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN 852
Query: 360 ETKCSNGTYGEDCAFVCADCGSGHC 384
+C +G DC+ V CG C
Sbjct: 853 SCRCLDGR--RDCSKVW--CGWKPC 873
Score = 94.4 bits (233), Expect = 4e-19
Identities = 105/393 (26%), Positives = 134/393 (34%), Gaps = 87/393 (22%)
Query: 99 RCRHGYFGANCDTKC-PRQ-------------------FWGPDCKE-LC--SCH-PHGQC 134
RC Y+ A C+ C PR + G +CKE +C C+ HG C
Sbjct: 197 RCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC 256
Query: 135 EDVTGQCTCHARRWGARCEHACQ---CQHGTCHPRSGACRCEPGWWGAQC-ASACYCSAT 190
V G+C C G C+ C HG+C C CE W G C YC +
Sbjct: 257 -TVPGECRCSYGWQGRFCDECVPYPGCVHGSC-VEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 191 SRC---------DPQTGACLCHAGWWGRSCNN-QCACNSSPCEQQSGRCQCRERTFGARC 240
C +P C C G+ GR+C + AC S+PC C E G C
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG---SCHEVPSGFEC 371
Query: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREP-------CPAGFYGLGCRRRCGQCKGQQ 293
C CA P G C + CP + G C+ C+GQ
Sbjct: 372 HCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ- 430
Query: 294 PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCS---HRC--PPCRDGHACNHVT-GKC 347
C TC+ NG +C C GF G C C PC G C + G
Sbjct: 431 -CQHGG----TCKDLVNGYQC--VCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 483
Query: 348 TRCNAGWIGDRCE--------TKCSNGT--YGEDCAFVCA---DCGSGHCDF-----QSG 389
C G+ G CE + C NG Y + + CA D G +C G
Sbjct: 484 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG 543
Query: 390 RCLCSPGVHGPHCNVTCPPGLHGADCAQACSCH 422
C G C PG+ G + C H
Sbjct: 544 ACRVIDG-----CGSDAGPGMPGTAASGVCGPH 571
Score = 63.9 bits (154), Expect = 6e-10
Identities = 70/307 (22%), Positives = 98/307 (31%), Gaps = 108/307 (35%)
Query: 228 RCQCRERTFGARCDRYC---------------------------QCFRGRCH-------- 252
R +C E + A C+++C +C C
Sbjct: 195 RVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHG 254
Query: 253 --PVDGTCACEPGYRGKYCRE------------------PCPAGFYGLGCRRRCGQCKGQ 292
V G C C G++G++C E C + GL C + C
Sbjct: 255 GCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 293 QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGC---SHRCP--PCRDGHACNHV-TGK 346
PCT G C+ EP + +C C G+ G C H C PC +G +C+ V +G
Sbjct: 315 HPCTNG-GTCINAEP--DQYRC--TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGF 369
Query: 347 CTRCNAGWIGDRC-------------------------ETKCSNGTYGEDCAFVCADCGS 381
C +GW G C E C G C DC
Sbjct: 370 ECHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDC-R 428
Query: 382 GHC-------DFQSG-RCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHE-DTCDPVTGA 432
G C D +G +C+C G G HC L +CA + CH C+ +
Sbjct: 429 GQCQHGGTCKDLVNGYQCVCPRGFGGRHCE------LERDECASS-PCHSGGLCEDLADG 481
Query: 433 CHLETNQ 439
H Q
Sbjct: 482 FHCHCPQ 488
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 126 bits (316), Expect = 1e-28
Identities = 113/418 (27%), Positives = 158/418 (37%), Gaps = 91/418 (21%)
Query: 73 DECGIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-----PDCKELC 126
D C C+ T + + +C + G+C C+ G C+ +C F+ PD C
Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCSPC 694
Query: 127 SCHPHGQ------CEDVTGQCTCHARRWGARCEHA-----------------CQCQ-HGT 162
+C+ G C +GQC C A G RC+H CQC HG+
Sbjct: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGS 754
Query: 163 ----CHPRSGACRCEPGWWGAQC--------------ASACYCSATSR-----CDPQTGA 199
C+P SG C C+ G QC AC C C+ +TG
Sbjct: 755 VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQ 814
Query: 200 CLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVDGT 257
C+C GR CN N + S C CD+ G C+ G
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFLC------LPCNCDK-TGTINGSLLCNKSTGQ 867
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCR--RRCGQCK----GQQPCTVAE---GRCLTCEPG 308
C C+ G G C + C Y L + C C+ G P T+ + G+CL C P
Sbjct: 868 CPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPN 925
Query: 309 WNGTKCDQPCATGFY-GEGCSHRCPPCRD------GHACNHVTGKCTRCNAGWIGDRCET 361
G +C+Q C GFY G + C PC H CN +TG+C +A G RC+
Sbjct: 926 RQGRRCNQ-CQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD- 983
Query: 362 KCSNGTYGED--------CAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
+C + +G D C + + C +G+C C V G C+ P H
Sbjct: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041
Score = 112 bits (281), Expect = 1e-24
Identities = 120/466 (25%), Positives = 161/466 (34%), Gaps = 125/466 (26%)
Query: 80 CEGNSTCSENEVCVRPGECRCRHGYF--GANCDTKCPR----------QFWGPDCKELCS 127
C+ + + +P C C F G +CD P Q + +CK C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-CQ 576
Query: 128 CHPHGQ-CE---DVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR------------ 171
C+ H + C V H R G C+ C+H T C+
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCD---DCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 172 ----CEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN--------------- 212
C+P C + + + CD G C C GR CN
Sbjct: 634 AIDVCKP----CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 213 --NQCACNSS-------PCEQQSGRCQCRERTFGARCDRY-----------------CQC 246
+ C CN+S C Q SG+C+C+ G RCD CQC
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 247 -----FRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQCKGQQP---C 295
C+P G C C+ +G C + C FYGL C+ G P C
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFY-GEGCSHRCPPC--------RDGHACNHVTGK 346
G+C+ C+P G +C++ FY + S C PC CN TG+
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQ 867
Query: 347 CTRCNAGWIGDRCETKCSNGTYG------EDCAFV-CADCGS---GHCDFQSGRCLCSPG 396
C C G G RC +C Y + C C G+ CD SG+CLC P
Sbjct: 868 CP-CKLGVTGLRC-NQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPN 925
Query: 397 VHGPHCNVTCPPGLH----GADCAQACSCH-----EDTCDPVTGAC 433
G CN C PG + A CSCH C+ +TG C
Sbjct: 926 RQGRRCN-QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQC 970
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 126 bits (316), Expect = 1e-28
Identities = 113/418 (27%), Positives = 158/418 (37%), Gaps = 91/418 (21%)
Query: 73 DECGIAVCEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPRQFWG-----PDCKELC 126
D C C+ T + + +C + G+C C+ G C+ +C F+ PD C
Sbjct: 636 DVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCN-QCQNGFYNLQELDPDGCSPC 694
Query: 127 SCHPHGQ------CEDVTGQCTCHARRWGARCEHA-----------------CQCQ-HGT 162
+C+ G C +GQC C A G RC+H CQC HG+
Sbjct: 695 NCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGS 754
Query: 163 ----CHPRSGACRCEPGWWGAQC--------------ASACYCSATSR-----CDPQTGA 199
C+P SG C C+ G QC AC C C+ +TG
Sbjct: 755 VNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKACDCDTAGSLPGTVCNAKTGQ 814
Query: 200 CLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR--CHPVDGT 257
C+C GR CN N + S C CD+ G C+ G
Sbjct: 815 CICKPNVEGRQCNKCLEGNFYLRQNNSFLC------LPCNCDK-TGTINGSLLCNKSTGQ 867
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCR--RRCGQCK----GQQPCTVAE---GRCLTCEPG 308
C C+ G G C + C Y L + C C+ G P T+ + G+CL C P
Sbjct: 868 CPCKLGVTGLRCNQ-CEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCL-CVPN 925
Query: 309 WNGTKCDQPCATGFY-GEGCSHRCPPCRD------GHACNHVTGKCTRCNAGWIGDRCET 361
G +C+Q C GFY G + C PC H CN +TG+C +A G RC+
Sbjct: 926 RQGRRCNQ-CQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDASIAGQRCD- 983
Query: 362 KCSNGTYGED--------CAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLH 411
+C + +G D C + + C +G+C C V G C+ P H
Sbjct: 984 QCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASH 1041
Score = 112 bits (281), Expect = 1e-24
Identities = 120/466 (25%), Positives = 161/466 (34%), Gaps = 125/466 (26%)
Query: 80 CEGNSTCSENEVCVRPGECRCRHGYF--GANCDTKCPR----------QFWGPDCKELCS 127
C+ + + +P C C F G +CD P Q + +CK C
Sbjct: 518 CQCHGHADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFNCKP-CQ 576
Query: 128 CHPHGQ-CE---DVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACR------------ 171
C+ H + C V H R G C+ C+H T C+
Sbjct: 577 CNSHSKSCHYNISVDPFPFEHFRGGGGVCD---DCEHNTTGRNCELCKDYFFRQVGADPS 633
Query: 172 ----CEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCN--------------- 212
C+P C + + + CD G C C GR CN
Sbjct: 634 AIDVCKP----CDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 213 --NQCACNSS-------PCEQQSGRCQCRERTFGARCDRY-----------------CQC 246
+ C CN+S C Q SG+C+C+ G RCD CQC
Sbjct: 690 GCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQC 749
Query: 247 -----FRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGL---GCRRRCGQCKGQQP---C 295
C+P G C C+ +G C + C FYGL C+ G P C
Sbjct: 750 NLHGSVNKFCNPHSGQCECKKEAKGLQC-DTCRENFYGLDVTNCKACDCDTAGSLPGTVC 808
Query: 296 TVAEGRCLTCEPGWNGTKCDQPCATGFY-GEGCSHRCPPC--------RDGHACNHVTGK 346
G+C+ C+P G +C++ FY + S C PC CN TG+
Sbjct: 809 NAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKSTGQ 867
Query: 347 CTRCNAGWIGDRCETKCSNGTYG------EDCAFV-CADCGS---GHCDFQSGRCLCSPG 396
C C G G RC +C Y + C C G+ CD SG+CLC P
Sbjct: 868 CP-CKLGVTGLRC-NQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVPN 925
Query: 397 VHGPHCNVTCPPGLH----GADCAQACSCH-----EDTCDPVTGAC 433
G CN C PG + A CSCH C+ +TG C
Sbjct: 926 RQGRRCN-QCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQC 970
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 124 bits (312), Expect = 3e-28
Identities = 135/531 (25%), Positives = 180/531 (33%), Gaps = 159/531 (29%)
Query: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCD 110
R VCRA + P C + C + C+ TC EC C G+ G NC+
Sbjct: 203 RCVCRATHTG-PNC----ERPYVPCSPSPCQNGGTCRPTGDVTH--ECACLPGFTGQNCE 255
Query: 111 -------------------------TKCPRQFWGPDCKELC--------SCHPHGQCEDV 137
+CP ++ G C E +C G C +
Sbjct: 256 ENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNT 315
Query: 138 TG--QCTCHARRWGARCEH------ACQCQHG-TCHPR--SGACRCEPGWWGAQC--ASA 184
G C C G C + C HG TCH R S C C G G C A
Sbjct: 316 HGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA 375
Query: 185 CY---CSATSRCD--PQTG--ACLCHAGWWGRSCN---NQCACNSSPCEQQ--------S 226
C C+ S CD P G C C +G+ G +C+ ++C+ ++PCE S
Sbjct: 376 CISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGS 435
Query: 227 GRCQCRERTFGARCD-RYCQCFRGRCHPVDGT---------CACEPGYRGKYCRE----- 271
CQC + G RC+ +C C D T C C PGY G +C
Sbjct: 436 FECQCLQGYTGPRCEIDVNECVSNPCQN-DATCLDQIGEFQCICMPGYEGVHCEVNTDEC 494
Query: 272 --------------------PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL-------- 303
CP GF G C+ +C PC +CL
Sbjct: 495 ASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDEC-ASTPCKNG-AKCLDGPNTYTC 552
Query: 304 TCEPGWNGTKCD--------QPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWI 355
C G+ GT C+ PC G +G + CR G+ +H C++
Sbjct: 553 VCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC 612
Query: 356 --GDRCETK-------CSNGTYGEDCAFVCADCGSGHCDFQSGRCL---------CSPGV 397
G C+ + C GT G +C DC S CD SG CL C PG
Sbjct: 613 RHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCD--SGTCLDKIDGYECACEPGY 670
Query: 398 HGPHCNV--------------TCPPGLHGADCAQACSCHEDTCDPVTGACH 434
G CN+ TC G++G C H+ TC C+
Sbjct: 671 TGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECN 721
Score = 118 bits (295), Expect = 3e-26
Identities = 136/539 (25%), Positives = 172/539 (31%), Gaps = 164/539 (30%)
Query: 45 ELNP-RGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRP---GECRC 100
+ NP G+ +C P C+ Q DEC + G + C C+ EC+C
Sbjct: 388 DTNPVNGKAICTCPSGYTGPACS---QDVDECSL----GANPCEHAGKCINTLGSFECQC 440
Query: 101 RHGYFGANCD---TKCPRQFWGPDCKEL-------CSCHPHGQ---CEDVTGQCTCHARR 147
GY G C+ +C D L C C P + CE T +C
Sbjct: 441 LQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCL 500
Query: 148 WGARC-----EHACQCQHG----TCHPRSGACRCEPGWWGAQCASA-----CYCSA---- 189
RC E C+C G C C P GA+C C C+
Sbjct: 501 HNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTG 560
Query: 190 ------TSRCDPQ------------TGACLCHAGWWGRSC-NNQCACNSSPCEQQSGRCQ 230
CDP T CLC G+ G C N C+S PC + G CQ
Sbjct: 561 THCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPC-RHGGTCQ 619
Query: 231 ---------CRERTFGARCD------RYCQCFRGRC-HPVDG-TCACEPGYRGKYCR--- 270
C + T G C+ C G C +DG CACEPGY G C
Sbjct: 620 DRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINI 679
Query: 271 -----EP-----------------CPAGFYGLGCRRRCGQCKGQQPCTVAEGRC------ 302
P CP G++ C +C PC G C
Sbjct: 680 DECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC-NSNPC--VHGACRDSLNG 736
Query: 303 --LTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVT-GKCTRCNAGWIGDRC 359
C+PGW+GT CD C PC +G C +T G C G+ G C
Sbjct: 737 YKCDCDPGWSGTNCD------INNNECESN--PCVNGGTCKDMTSGYVCTCREGFSGPNC 788
Query: 360 ETK--------CSN-GT----------------YGEDCAFVCADCGSGHC---------- 384
+T C N GT G C V A C C
Sbjct: 789 QTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSE 848
Query: 385 DFQSGRCLCSPGVHGPHCNV-----TCPPGLHGADCAQACSCHEDTCDPVTGACHLETN 438
D++S C+C G G C V P HGA C + C + ET+
Sbjct: 849 DYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Score = 106 bits (264), Expect = 1e-22
Identities = 130/515 (25%), Positives = 165/515 (32%), Gaps = 174/515 (33%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECR---------CRHGYFGANCDTK-- 112
C GW G C I N+ C N CV G C+ CR G+ G NC T
Sbjct: 741 CDPGW--SGTNCDI----NNNECESNP-CVNGGTCKDMTSGYVCTCREGFSGPNCQTNIN 793
Query: 113 -----------------------CPRQFWGPDCKELCS------CHPHGQC---EDVTG- 139
C + G C+ + + C G+C ED
Sbjct: 794 ECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESF 853
Query: 140 QCTCHARRWGARCE---HAC---QCQHG-TCHPRSGA--CRCEPGWWGAQCAS------- 183
C C G CE + C C+HG +C G C C+ G+ G C +
Sbjct: 854 SCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRP 913
Query: 184 -ACYCSATSRCDPQTGACLCHAGWWGRSCN---NQCACNSSPCEQ--------QSGRCQC 231
C+ + T C C G+ G C N+CA S PC S C C
Sbjct: 914 NPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINECA--SDPCRNGANCTDCVDSYTCTC 971
Query: 232 RERTFGARCDRYC------QCFRG-RCHPVDG----TCACEPGYRGKYC----------- 269
G C+ CF G C VDG TC C PG+ G YC
Sbjct: 972 PAGFSGIHCENNTPDCTESSCFNGGTC--VDGINSFTCLCPPGFTGSYCQHDVNECDSQP 1029
Query: 270 --------------REPCPAGFYGLGCRRRCGQCKGQQPC--------TVAEGRCLTCEP 307
R CP G+ G C+ C PC T + RC C
Sbjct: 1030 CLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWC-DSSPCKNGGKCWQTHTQYRC-ECPS 1087
Query: 308 GWNGTKCDQP---CATGFYGEG------CSH--RCPPCRDGHACNHVTGKCTRCNAGWIG 356
GW G CD P C +G C H C + H C RC AG+ G
Sbjct: 1088 GWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHC--------RCQAGYTG 1139
Query: 357 DRCE--------TKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN----- 403
CE + C NG C D G+ C C G HG +C+
Sbjct: 1140 SYCEDLVDECSPSPCQNGA-------TCTDYLGGY------SCKCVAGYHGVNCSEEIDE 1186
Query: 404 VTCPPGLHGADCAQACSCHEDTCDPVTGACHLETN 438
P +G C + ++ +C T H E N
Sbjct: 1187 CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEIN 1221
Score = 95.5 bits (236), Expect = 2e-19
Identities = 124/502 (24%), Positives = 151/502 (30%), Gaps = 192/502 (38%)
Query: 119 GPDCKELC-SCHPHGQCEDVTGQ--CTCHARRWGARCEHACQC------QHGTCH--PRS 167
GP C + +C G+CE G C C G RC+ C GTCH R
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
Query: 168 G----ACRCEPGWWGAQCAS----ACY---CSATSRCDPQTGA---CLCHAGWWGRSCNN 213
G AC C G+ G C + AC C CD T C C GW G+SC
Sbjct: 81 GVADYACSCALGFSGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQ 140
Query: 214 QCACNSSPC------------------------------------------------EQQ 225
C S+PC E
Sbjct: 141 ADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVG 200
Query: 226 SGRCQCRERTFGARCDR-YCQCF------RGRCHP---VDGTCACEPGYRGKYCRE---- 271
S RC CR G C+R Y C G C P V CAC PG+ G+ C E
Sbjct: 201 SYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDD 260
Query: 272 ---------------------PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC-------- 302
CP + G C +C+ G C
Sbjct: 261 CPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYN 320
Query: 303 LTCEPGWNGTKCDQ---PCATG--FYGEGCSHR-------CP-----------------P 333
C GW G C + CA+ F+G C R CP P
Sbjct: 321 CVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNP 380
Query: 334 CRDGHAC--NHVTGK--CTRCNAGWIGDRC---------------------------ETK 362
C +G C N V GK CT C +G+ G C E +
Sbjct: 381 CNEGSNCDTNPVNGKAICT-CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQ 439
Query: 363 CSNGTYGEDCAFVCADCGSGHCDFQSG--------RCLCSPGVHGPHCNV-----TCPPG 409
C G G C +C S C + +C+C PG G HC V P
Sbjct: 440 CLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPC 499
Query: 410 LHGADCAQACSCHEDTCDPVTG 431
LH C +E C+ TG
Sbjct: 500 LHNGRCLD--KINEFQCECPTG 519
Score = 67.4 bits (163), Expect = 5e-11
Identities = 95/399 (23%), Positives = 127/399 (31%), Gaps = 81/399 (20%)
Query: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
C N TC + V C C G+ G C+ P C C
Sbjct: 1238 CFNNGTCVDQ---VGGYSCTCPPGFVGERCEGDVNECLSNP-----CDARGTQNCVQRVN 1289
Query: 140 Q--CTCHARRWGARCE---HACQ---CQHG-TCHPRSGA-----CRCEPGWWGAQCASAC 185
C C A G RCE + C+ C++G TC S C+C G+ GA C +
Sbjct: 1290 DFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDA 1349
Query: 186 YCSATSRC--------DPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFG 237
+ RC P++ CLC + G C SSPC G
Sbjct: 1350 RTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPA---SSPC-------------LG 1393
Query: 238 ARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTV 297
+P CEP + R CPA F GL C G
Sbjct: 1394 G-------------NPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGG------ 1434
Query: 298 AEGRCLTCEPGWNGTKCDQP-CATGFYGEGCSHRCPPCRDGHACNHVTGKCT-RCNAGWI 355
G P C+ P C + CS +C + HAC G C+ N W
Sbjct: 1435 --GAGRDIPPPLIEEACELPECQEDAGNKVCSLQC----NNHACGWDGGDCSLNFNDPW- 1487
Query: 356 GDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADC 415
C Y D + C S C F C + G P + C C
Sbjct: 1488 -KNCTQSLQCWKYFSD-GHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHC 1545
Query: 416 AQACSCHEDTCDPVTGACHLETNQRKGVMGAGALLVLLV 454
Q C+ E D + A H+ + AG L+V+++
Sbjct: 1546 DQGCNSAECEWDGLDCAEHVPER-----LAAGTLVVVVL 1579
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 124 bits (311), Expect = 4e-28
Identities = 126/477 (26%), Positives = 174/477 (36%), Gaps = 105/477 (22%)
Query: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCS-ENEVCVRPGECRCRHGYFGAN 108
G C G++ TC GW G EC A+C CS ++ C PG+CRC++G+ G
Sbjct: 208 GHYACDQNGNK--TCMEGW--MGPECNRAICRQG--CSPKHGSCKLPGDCRCQYGWQGLY 261
Query: 109 CD------------------TKCPRQFWGPDC-KELCSCHPH------GQCEDVTG---- 139
CD C + G C K+L C H G C + TG
Sbjct: 262 CDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSN-TGPDKY 320
Query: 140 QCTCHARRWGARC---EHACQCQHGTCHPRSGA--------CRCEPGWWGAQCA------ 182
QC+C G C EHAC CH R C C PGW G C+
Sbjct: 321 QCSCPEGYSGPNCEIAEHACLSD--PCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDC 378
Query: 183 SACYCSATSRCDPQTGA--CLCHAGWWGRSCN---NQC----ACNSSPCEQ--QSGRCQC 231
S CS C C+C W G++C N+C N+ C+ S C C
Sbjct: 379 SPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDC 438
Query: 232 RERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
G CD G+C +C G C CP G+ G C R +C
Sbjct: 439 LPGWMGQNCDININDCLGQC---QNDASCRDLVNGYRC--ICPPGYAGDHCERDIDEC-A 492
Query: 292 QQPC--------TVAEGRCLTCEPGWNGTKCD--------QPCATG--FYGEGCSH--RC 331
PC + +CL C G++G C PC G Y + +C
Sbjct: 493 SNPCLNGGHCQNEINRFQCL-CPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKC 551
Query: 332 PPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCAD-CG-SGHCDFQSG 389
P +G C+H+ C R + D C ++ E ++ ++ CG G C QSG
Sbjct: 552 PEDYEGKNCSHLKDHC-RTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSG 610
Query: 390 ---RCLCSPGVHGPHC-----NVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETN 438
C C+ G G +C + P +G C + ++ C + ETN
Sbjct: 611 GKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETN 667
Score = 93.6 bits (231), Expect = 7e-19
Identities = 120/468 (25%), Positives = 158/468 (33%), Gaps = 130/468 (27%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVC---VRPGECRCRHGYFGANCDTKCPRQFWGP 120
C GW Q + I C G C + C V C C GY G +C+
Sbjct: 438 CLPGWMGQNCDININDCLGQ--CQNDASCRDLVNGYRCICPPGYAGDHCER--------- 486
Query: 121 DCKELCS--CHPHGQCEDVTG--QCTCHARRWGARCE---HACQ---CQHGT-CHPRSGA 169
D E S C G C++ QC C G C+ C+ CQ+G C+ R+
Sbjct: 487 DIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASD 546
Query: 170 --CRCEPGWWGAQCA---------------------------------SACYCSATSRCD 194
C+C + G C+ S+ C +C
Sbjct: 547 YFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCK 606
Query: 195 PQTGA---CLCHAGWWGRSCN-NQCACNSSPCEQ--------QSGRCQCRERTFGARCDR 242
Q+G C C+ G+ G C+ N C S+PC S +C C + GA C+
Sbjct: 607 SQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCET 666
Query: 243 YCQ-CFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA--- 298
C + CH GTC YC C G+ G C R QC + C
Sbjct: 667 NINDCSQNPCHN-GGTC--RDLVNDFYC--DCKNGWKGKTCHSRDSQCD-EATCNNGGTC 720
Query: 299 --EG---RCLTCEPGWNGTKCD---------QPCATG----FYGEGCSHRCPPCRDGHAC 340
EG +C+ C GW GT C+ PC G GE + C +G C
Sbjct: 721 YDEGDAFKCM-CPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPIC 779
Query: 341 NHVTGKCTR---CNAGWIGD-----RCETKCSNGTYGEDCAFVCADCGSGHCDFQSG--- 389
T C+ N+G D RCE C+ G G DC +C S C F +
Sbjct: 780 AQNTNDCSPHPCYNSGTCVDGDNWYRCE--CAPGFAGPDCRININECQSSPCAFGATCVD 837
Query: 390 -----RCLCSPGVHGPHC-----------NVTCPPGLHGADCAQACSC 421
RC+C PG G C P G D C C
Sbjct: 838 EINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC 885
Score = 87.4 bits (215), Expect = 5e-17
Identities = 99/405 (24%), Positives = 143/405 (35%), Gaps = 78/405 (19%)
Query: 48 PRGRNVCRAPGSQVPTCCAGW-----RQQGDECGIAVCEGNSTCSENEVCVRPGECRCRH 102
P G+ ++ G C G+ + ++C C TC + V +C C
Sbjct: 601 PHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDG---VNSYKCICSD 657
Query: 103 GYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQC-----------TCHARRWGAR 151
G+ GA C+T DC + CH G C D+ TCH+R ++
Sbjct: 658 GWEGAYCETNIN------DCSQN-PCHNGGTCRDLVNDFYCDCKNGWKGKTCHSR--DSQ 708
Query: 152 CEHACQCQHGTCHPRSGA--CRCEPGWWGAQCASA---------CYCSATSRCDPQTGAC 200
C+ A GTC+ A C C GW G C A C+ T + ++ C
Sbjct: 709 CDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTC 768
Query: 201 LCHAGWWGRSC-NNQCACNSSPCEQQSG--------RCQCRERTFGARCD---RYCQ--- 245
+C GW G C N C+ PC RC+C G C CQ
Sbjct: 769 VCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSP 828
Query: 246 -CFRGRC-HPVDG-TCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAE--- 299
F C ++G C C PG+ G C+E +G G K C +
Sbjct: 829 CAFGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDG-AKWDDDCNTCQCLN 887
Query: 300 GRCLTCEPGWNGTKCDQPCATGFYGEGC--SHRCPPCRDGHACNHVTGKCTRCNAGWIGD 357
GR + C W G + PC C C P D H C + +
Sbjct: 888 GR-IACSKVWCGPR---PCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSL-Q 942
Query: 358 RCETKCSNGTYGED-CAFVCADCGSGHCDFQSGRCLCSPGVHGPH 401
+TKC++ +Y +D CA + F + + SPG+ H
Sbjct: 943 PVKTKCTSDSYYQDNCA---------NITFTFNKEMMSPGLTTEH 978
Score = 52.0 bits (123), Expect = 2e-06
Identities = 49/176 (27%), Positives = 68/176 (38%), Gaps = 33/176 (18%)
Query: 270 REPCPAGFYGLGCRRRC---GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEG 326
R C +YG GC + C G C + TC GW G +C++ +G
Sbjct: 184 RVTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNK--TCMEGWMGPECNRAICR----QG 237
Query: 327 CSHRCPPCRDGHACNHVTGKCTRCNAGWIG---DRC--ETKCSNGTYGEDCAFVC-ADCG 380
CS + C+ + G C RC GW G D+C C +G E +C + G
Sbjct: 238 CSPKHGSCK-------LPGDC-RCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWG 289
Query: 381 SGHCDFQSGRC-LCSPGVHGPHCNVT--------CPPGLHGADCAQA-CSCHEDTC 426
CD C P ++G C+ T CP G G +C A +C D C
Sbjct: 290 GQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPC 345
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 119 bits (299), Expect = 9e-27
Identities = 141/521 (27%), Positives = 179/521 (34%), Gaps = 126/521 (24%)
Query: 3 GAGPRGAGPARRRGAGGPPSPLLPSLLLLLLLWMLPDTVAPQELN----PRGRNVCRAPG 58
G G RG RR + PP P + +L LLLLL P AP L+ G + P
Sbjct: 2 GPGARGRRRRRRPMSPPPPPPPVRALPLLLLL-AGPGAAAPPCLDGSPCANGGRCTQLPS 60
Query: 59 SQVPTCC-AGW----RQQGDECGIAVCEGNSTCSENEVC-VRPGECRCRHGYFGANCDTK 112
+ C GW Q D C C G C + V CRC G+ G +C
Sbjct: 61 REAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLP 120
Query: 113 CP----------RQFWGPDCKELCSCHPHGQ---CEDVTGQCTCHARRWGARCEHACQCQ 159
P R GPD + LCSC P Q C +C R G C H
Sbjct: 121 DPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDEC-----RVGEPCRHG---- 171
Query: 160 HGTC--HPRSGACRCEPGWWGAQCASACYCSATSRC---------DPQTGACLCHAGWWG 208
GTC P S C+C G+ G C + A S C T C C G+ G
Sbjct: 172 -GTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEG 230
Query: 209 RSCN---NQC----ACNSSPCEQ--QSGRCQCRERTFGARCDR---YCQCFRGRCH---- 252
++C + C N C + CQC G C CQ CH
Sbjct: 231 QNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGT 290
Query: 253 ---PVDG-TCACEPGYRGKYCRE-------------------------PCPAGFYGLGCR 283
+ G +C C G+ G+ C + CP G GL C
Sbjct: 291 CFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCACPMGKTGLLCH 350
Query: 284 RR----CGQCKGQQPCTV--AEGRCL-TCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRD 336
C C GR + TC PG+ G CDQ + CS PC
Sbjct: 351 LDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDV------DECSIGANPCEH 404
Query: 337 GHACNHVTGK-CTRCNAGWIGDRCET---KCSNGTYGEDCA-------FVCADCGSG--- 382
C + G +C G+ G RCET +C +G F C C +G
Sbjct: 405 LGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCI-CMAGFTG 463
Query: 383 -HCDFQSGRCLCSPGVHGPHC-------NVTCPPGLHGADC 415
+C+ C SP V+G C + TCP G G+ C
Sbjct: 464 TYCEVDIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTC 504
Score = 119 bits (299), Expect = 9e-27
Identities = 132/496 (26%), Positives = 160/496 (32%), Gaps = 144/496 (29%)
Query: 57 PGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
PG P C + DEC C G TC+++ V C C GY G +C+ P
Sbjct: 877 PGFAGPRCA----RDVDECLSNPC-GPGTCTDH---VASFTCTCPPGYGGFHCEQDLP-- 926
Query: 117 FWGPDCKELCSCHPHGQCEDVTGQ--CTCHARRWGARCEHACQ------CQHG----TCH 164
DC SC G C D C C GA C+H C HG H
Sbjct: 927 ----DCSP-SSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAH 981
Query: 165 PRSGACRCEPGWWGAQC------ASACYCSATSRCDPQTGA-CLCHAGWWGRSC------ 211
P C C + G QC S C RC QTGA CLC GW GR C
Sbjct: 982 P-GFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRC-VQTGAYCLCPPGWSGRLCDIRSLP 1039
Query: 212 ---------------------------NNQCAC----NSSPCEQQSGRCQCRERTFGARC 240
++ C C S CEQ+ C + G C
Sbjct: 1040 CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC 1099
Query: 241 DRY-----CQCFRG----RCHPVDGTCACEPGYRGKYCRE-------PCPAGFYGLGCRR 284
Y C+C G C CA +P G C + CP G G+ C
Sbjct: 1100 RGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEI 1159
Query: 285 RCGQCKGQQPCTVAEGRCL---TCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACN 341
C G P + RCL TC G +C C G+ G C CR G
Sbjct: 1160 NEDDC-GPGPPLDSGPRCLHNGTCVDLVGGFRC--TCPPGYTGLRCEADINECRSGACHA 1216
Query: 342 HVTGKCTR---------CNAGWIGDRCET------------------------------K 362
T C + C+AG+ G RC+T
Sbjct: 1217 AHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCH 1276
Query: 363 CSNGTYGEDCAFVCADCGSGHCDF--------QSGRCLCSPGVHGPHCN--VTCPPGLHG 412
C+ +G C V C C + RC C PG+ GP C PPG
Sbjct: 1277 CAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASN 1336
Query: 413 ADCAQACSCHEDTCDP 428
A CA A H +C P
Sbjct: 1337 ASCAAAPCLHGGSCRP 1352
Score = 114 bits (285), Expect = 4e-25
Identities = 123/474 (25%), Positives = 146/474 (30%), Gaps = 150/474 (31%)
Query: 56 APGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANC------ 109
APG C Q DEC C C + V CRC G G NC
Sbjct: 571 APGYTGTRC----ESQVDECRSQPCRHGGKCLD---LVDKYLCRCPSGTTGVNCEVNIDD 623
Query: 110 ------------------DTKCPRQFWGPDCK----ELCS--CHPHGQCEDVTG--QCTC 143
D C F GP C E S C G C D +C C
Sbjct: 624 CASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLC 683
Query: 144 HARRWGARC---EHACQ---CQHGTCHPRSGA--CRCEPGWWGAQCASA----------C 185
C H C C HG C+ G C CEPGW G +C+ + C
Sbjct: 684 PPGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPC 743
Query: 186 YCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQ 245
T D C C G GR C C +PCE
Sbjct: 744 RAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNPCEH--------------------- 782
Query: 246 CFRGRCHPVDG---TCACEPGYRGKYCRE-------PCPAGFYGLGCRRRCGQCKGQQPC 295
GRC G C+C G++G C++ P P G +G+ C G C
Sbjct: 783 --GGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGI-----CTNLAGSFSC 835
Query: 296 TVAEGRCLTCEPGWNGTKCDQ-------------------------PCATGFYGEGCSH- 329
TC G+ G CDQ C GF G C+
Sbjct: 836 --------TCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARD 887
Query: 330 --RC--PPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCA-FVCADCGSGHC 384
C PC G +HV C G+ G CE DC+ C + G+
Sbjct: 888 VDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDL------PDCSPSSCFNGGTCVD 941
Query: 385 DFQSGRCLCSPGVHGPHCN-----VTCPPGLHGADCAQA-----CSCHEDTCDP 428
S CLC PG G HC P LHG C+ A C+C E P
Sbjct: 942 GVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGP 995
Score = 114 bits (284), Expect = 5e-25
Identities = 125/515 (24%), Positives = 159/515 (30%), Gaps = 156/515 (30%)
Query: 46 LNPRGRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYF 105
LN G C+ P C C + C TC ++ +C C G+
Sbjct: 175 LNTPGSFRCQCPAGYTGPLC---ENPAVPCAPSPCRNGGTCRQSGDLTY--DCACLPGFE 229
Query: 106 GANCDTK---CPRQFWGPDCKELCSCHPHGQCEDV--TGQCTCHARRWGARCEH---ACQ 157
G NC+ CP C G C D T C C G C CQ
Sbjct: 230 GQNCEVNVDDCPGH----------RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVDECQ 279
Query: 158 CQHGTCHPRSG--------ACRCEPGWWGAQCA--------SACYCSATSRCDPQTGACL 201
Q CH +C C GW G C+ + C+ AT + C
Sbjct: 280 LQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRVASFYCA 339
Query: 202 CHAGWWGRSCNNQCACNSSPCEQQ--------SGR--CQCRERTFGARCDR-YCQC---- 246
C G G C+ AC S+PC + +GR C C G CD+ +C
Sbjct: 340 CPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVDECSIGA 399
Query: 247 ----FRGRCHPVDGT--CACEPGYRGKYCREP-------------------------CPA 275
GRC G+ C C GY G C C A
Sbjct: 400 NPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLDRIGQFTCICMA 459
Query: 276 GFYGLGCRRRCGQCKGQQPCT-------VAEGRCLTCEPGWNGTKC-------------- 314
GF G C +C+ PC G TC G++G+ C
Sbjct: 460 GFTGTYCEVDIDECQ-SSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRN 518
Query: 315 -----DQP------CATGFYGEGCSHRC-----PPCRDGHACNHVTGKCTRCNAGWIGDR 358
DQP CA GF G C PC G + + C G+ G R
Sbjct: 519 GAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTR 578
Query: 359 CET-------------------------KCSNGTYGEDCAFVCADCGSGHCDFQSGR--- 390
CE+ +C +GT G +C DC S C F R
Sbjct: 579 CESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGI 638
Query: 391 ----CLCSPGVHGPHCNVTCPPGLHGADCAQACSC 421
C+C PG GP CNV + C + SC
Sbjct: 639 NRYDCVCQPGFTGPLCNVEINE-CASSPCGEGGSC 672
Score = 106 bits (264), Expect = 1e-22
Identities = 127/479 (26%), Positives = 163/479 (34%), Gaps = 132/479 (27%)
Query: 37 LPDTVAPQELNPRGRNVCRAPGSQVP-------TCCAG-----WRQQGDECGIAVCEGNS 84
LP A ++ R +C+A G V C G Q+ D C C+
Sbjct: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGG 1097
Query: 85 TCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCS--CHPHGQCEDVTGQ-- 140
TC + C C GY G NC+ D E S C G C D+ +
Sbjct: 1098 TCRGY---MGGYMCECLPGYNGDNCED---------DVDECASQPCQHGGSCIDLVARYL 1145
Query: 141 CTCHARRWGARCE-------------HACQCQH-GTCHPRSGA--CRCEPGWWGAQC--- 181
C+C G CE +C H GTC G C C PG+ G +C
Sbjct: 1146 CSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEAD 1205
Query: 182 -----ASACYCSATSRC--DPQTG-ACLCHAGWWGRSCNNQCA-CNSSPCEQQSGRCQ-- 230
+ AC+ + T C DP G CLCHAG+ G C + C S PC Q G+C+
Sbjct: 1206 INECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPC-QHGGQCRPS 1264
Query: 231 ------------CRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFY 278
C + +G RC+R + R PV C P RG C CP G
Sbjct: 1265 PGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTP--RGPRCA--CPPGLS 1320
Query: 279 GLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGH 338
G CR G G + A CL +G C F+ RC
Sbjct: 1321 GPSCRSFPGSPPGASNASCAAAPCL------HGGSCRPAPLAPFF------RCA------ 1362
Query: 339 ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGED--CAFVCA-----------DCGSGHCD 385
C GW G RCE + E+ C +C S C
Sbjct: 1363 -----------CAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCG 1411
Query: 386 FQSGRCLCSPGVHGPHCN-VTCPPGLHGADCAQACS----------CH----EDTCDPV 429
+ G C S G C + C + + C ACS CH E TC+PV
Sbjct: 1412 WDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPV 1470
Score = 94.0 bits (232), Expect = 5e-19
Identities = 79/283 (27%), Positives = 103/283 (36%), Gaps = 54/283 (19%)
Query: 174 PGWWGAQCASACYCSATSRCDP---QTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQ 230
PG C C+ RC + ACLC GW G C + C+S PC +GR
Sbjct: 36 PGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPC---AGRGV 92
Query: 231 CRERTFGARCDRYCQC---FRGRCHPVDGTCACEPGYRGKYCRE--------PCPAGFYG 279
C+ C+C FRG + C P G C CP G+ G
Sbjct: 93 CQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQG 152
Query: 280 LGCRRRCGQCKGQQPCTVAEGRCLT--------CEPGWNGTKCDQPCATGFYGEGCSHRC 331
CR +C+ +PC G CL C G+ G C+ P C+
Sbjct: 153 RSCRSDVDECRVGEPCRHG-GTCLNTPGSFRCQCPAGYTGPLCENPAVP------CAP-- 203
Query: 332 PPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRC 391
PCR+G C +G T + C G G++C DC GH G C
Sbjct: 204 SPCRNGGTCRQ-SGDLT----------YDCACLPGFEGQNCEVNVDDC-PGHRCLNGGTC 251
Query: 392 LCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACH 434
+ GV+ +C CPP G Q C+ D C ACH
Sbjct: 252 V--DGVNTYNCQ--CPPEWTG----QFCTEDVDECQLQPNACH 286
Score = 77.0 bits (188), Expect = 7e-14
Identities = 94/368 (25%), Positives = 112/368 (30%), Gaps = 91/368 (24%)
Query: 51 RNVCRAPGSQVPTCCAGWRQQGDECGIAV-CEGNSTCSENEVCVR---PGECRCRHGYFG 106
R +C P + C D+CG + C N CV C C GY G
Sbjct: 1143 RYLCSCPPGTLGVLC---EINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTG 1199
Query: 107 ANCDTK----------------------------CPRQFWGPDCKELCS------CHPHG 132
C+ C F GP C+ + S C G
Sbjct: 1200 LRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGG 1259
Query: 133 QCEDVTGQ-----CTCHARR--WGARCEHAC------QCQHGT-CH--PRSGACRCEPGW 176
QC G TCH + WG RCE QC G C PR C C PG
Sbjct: 1260 QCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGL 1319
Query: 177 WGAQCAS--------------ACYCSATSRCDPQTGA----CLCHAGWWGRSCNNQCACN 218
G C S A C C P A C C GW G C A
Sbjct: 1320 SGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAP 1379
Query: 219 SSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCRE-PCPAGF 277
E + R C+ + RCDR +C C G C+ G + C C F
Sbjct: 1380 EVSEEPRCPRAACQAKRGDQRCDR--ECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLF 1437
Query: 278 YGLGCRRRCGQ--CKGQQPCTVAEGRCLTCEPGWN--------GTKCDQPCAT---GFYG 324
C C C A GR TC P + +CDQ C T G+ G
Sbjct: 1438 NNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNTEECGWDG 1497
Query: 325 EGCSHRCP 332
C+ P
Sbjct: 1498 LDCASEVP 1505
Score = 37.7 bits (86), Expect = 0.046
Identities = 55/222 (24%), Positives = 79/222 (35%), Gaps = 32/222 (14%)
Query: 566 APAESRDPEVPTV-PAEAPAPSPVPLTTPASAEEAIPLPASSDSERSASSVEGPGGALYA 624
+P +S D P P +P P+ A+ A+ L R+ + PGG + +
Sbjct: 2100 SPVDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVSLAQLGGPGRAGLGRQPPGGCVLS 2159
Query: 625 -------RVARREAR--PARARGEIGGLSLSPSPERRKPPPP-DPATKPKVSWIHGKHSA 674
V AR P G L L+P P+ P P P +P
Sbjct: 2160 LGLLNPVAVPLDWARLPPPAPPGPSFLLPLAPGPQLLNPGTPVSPQERPPPY-------L 2212
Query: 675 AAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGL-------P 727
A G P G+ ++P ++ R PS+ T SP +P PP L P
Sbjct: 2213 AVPGHGEEYPAAGAHSSPPKARFLRVPSEHPYLTPSPESPE-HWASPSPPSLSDWSESTP 2271
Query: 728 EEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASML 769
ATA A + A P PL P+ A+A + L
Sbjct: 2272 SPATATGAMATTTGALPAQPLPLSV------PSSLAQAQTQL 2307
Score = 37.4 bits (85), Expect = 0.060
Identities = 54/203 (26%), Positives = 77/203 (37%), Gaps = 32/203 (15%)
Query: 656 PPDPATKPKVSWIHGKHSAAAAGRAPSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPR 715
P P + P G H P PG +AA S SK+ R P K+ + R
Sbjct: 2027 PSGPRSPP------GPHGLGPLLCPPGAFLPGLKAAQSGSKKSRRPPGKAGLGPQGPRGR 2080
Query: 716 TRDPTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRR------RSPAKRAEAASML 769
+ T PG +++ +P + +PRP G P A A ++
Sbjct: 2081 GKKLTLACPGPLADSSVTLSP----VDSLDSPRPFGGPPASPGGFPLEGPYAAATATAVS 2136
Query: 770 AADVRGKTRS-LGRAE-----VALGAQGPREKPAPPQKAKRSVPPASPARAPPATETPGP 823
A + G R+ LGR ++LG P A P R PPA P + PGP
Sbjct: 2137 LAQLGGPGRAGLGRQPPGGCVLSLGLLNP---VAVPLDWARLPPPAPPGPSFLLPLAPGP 2193
Query: 824 EKAATDLPAPETPRKKTPIQKPP 846
+ L P TP +P ++PP
Sbjct: 2194 Q-----LLNPGTP--VSPQERPP 2209
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 119 bits (297), Expect = 2e-26
Identities = 118/425 (27%), Positives = 152/425 (35%), Gaps = 86/425 (20%)
Query: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANC 109
G C G++ C GW G EC AVC+ C PGECRC +G+ G C
Sbjct: 219 GHYTCDQYGNKA--CMDGW--MGKECKEAVCKQGCNLLHGG-CTVPGECRCSYGWQGRFC 273
Query: 110 DTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCE---HACQCQH-----G 161
D P P C HG C + QC C G C+ + C H G
Sbjct: 274 DECVPY----PGC-------VHGSCVE-PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGG 321
Query: 162 TC---HPRSGACRCEPGWWGAQCASACYCSATSRCD--------PQTGACLCHAGWWGRS 210
TC P C C G+ G C A + ++ C P C C +GW G +
Sbjct: 322 TCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPT 381
Query: 211 C--------NNQCACNSSPCEQQSG-RCQCRERTFGARCDRYCQCFRGRCHPVDGTCACE 261
C +N CA + +Q G C C E+ GA C G+ P +C+
Sbjct: 382 CALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK--PCLNAFSCK 439
Query: 262 PGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATG 321
G YC C G+ G+ C C+GQ C TC+ NG +C C G
Sbjct: 440 NLIGGYYC--DCIPGWKGINCHINVNDCRGQ--CQHGG----TCKDLVNGYQC--VCPRG 489
Query: 322 FYGEGCS---HRC--PPCRDGHACNHVT-GKCTRCNAGWIGDRCE--------TKCSNGT 367
F G C C PC G C + G C G+ G CE + C NG
Sbjct: 490 FGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGA 549
Query: 368 --YGEDCAFVCA---DCGSGHCDF-----QSGRCLCSPGVHGPHCNVTCPPGLHGADCAQ 417
Y + + CA D G +C G C G C PG+ G +
Sbjct: 550 RCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDG-----CGSDAGPGMPGTAASG 604
Query: 418 ACSCH 422
C H
Sbjct: 605 VCGPH 609
Score = 115 bits (289), Expect = 1e-25
Identities = 121/430 (28%), Positives = 153/430 (35%), Gaps = 107/430 (24%)
Query: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVC---VRPGECRCRHGYFGANCDTK-------- 112
C GW+ G C I V + C C V +C C G+ G +C+ +
Sbjct: 449 CIPGWK--GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSP 506
Query: 113 -----------------CPRQFWGPDCK---ELCS---CHPHGQCEDVTGQ--CTCHARR 147
CP+ F GP C+ +LC C +C ++ G C C
Sbjct: 507 CHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDF 566
Query: 148 WGARCEHACQ-CQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTG---ACLCH 203
G C + C G C G C + G A++ C RC Q G +C+C
Sbjct: 567 GGKNCSVPREPCPGGACRVIDG-CGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICD 625
Query: 204 AGWWGRSCN-NQCACNSSPC--------EQQSGRCQCRERTFGARCDRYCQ-CF------ 247
+G+ G C+ N C PC E + RC C G CD C
Sbjct: 626 SGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHS 685
Query: 248 RGRCHPV--DGTCACEPGYRGKYCRE---PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRC 302
RGRC+ + D CAC+ G++GK C C A G G C RC
Sbjct: 686 RGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNG-----GTCYDSGDTF----RC 736
Query: 303 LTCEPGWNGTKC---------DQPCATG--FYGEGCSHRCPPCRDG---HACNHVTGKCT 348
C PGW G+ C PC G G G S C CRDG C H T C
Sbjct: 737 -ACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCI-CRDGWEGRTCTHNTNDCN 794
Query: 349 RC---NAGWIGD-----RCETKCSNGTYGEDCAFVCADCGSGHC--------DFQSGRCL 392
N G D RCE C+ G G DC +C S C + RC
Sbjct: 795 PLPCYNGGICVDGVNWFRCE--CAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCS 852
Query: 393 CSPGVHGPHC 402
C PG GP C
Sbjct: 853 CPPGRAGPRC 862
Score = 114 bits (285), Expect = 4e-25
Identities = 128/493 (25%), Positives = 174/493 (35%), Gaps = 147/493 (29%)
Query: 80 CEGNSTCSENEVCVRPG----ECRCRHGYFGANCDTK----------------------- 112
C + C+ C+ C C GY G NC+
Sbjct: 311 CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFE 370
Query: 113 --CPRQFWGPDCK---ELCSCHP---HGQCED-VTG-QCTCHARRWGARCE-HACQCQHG 161
CP + GP C + C+ +P G C D V G +C C + GA C+ A +C+
Sbjct: 371 CHCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGK 430
Query: 162 TCHPRSGA--------CRCEPGWWGAQC-------ASACYCSATSRCDPQTGACLCHAGW 206
C C C PGW G C C T + C+C G+
Sbjct: 431 PCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGF 490
Query: 207 WGRSCN-NQCACNSSPCEQ--------QSGRCQCRERTFGARCD---RYCQ---CFRG-R 250
GR C + C SSPC C C + G C+ C+ C G R
Sbjct: 491 GGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGAR 550
Query: 251 CHPVDGT--CACEPGYRGKYC---REPCPAGFYGLGCR--RRCGQCKGQ-QPCTVAEGRC 302
C+ ++G CAC + GK C REPCP G CR CG G P T A G C
Sbjct: 551 CYNLEGDYYCACPDDFGGKNCSVPREPCPGG----ACRVIDGCGSDAGPGMPGTAASGVC 606
Query: 303 LTCEPGWNGTKCDQP-------CATGFYGEGCSHRCP-----PCRDGHAC-NHVTGKCTR 349
G +G QP C +GF G C PCR+G C + V
Sbjct: 607 -----GPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCF 661
Query: 350 CNAGWIGDRCETK-------------------------CSNGTYGEDC--------AFVC 376
C +GW G+ C+T C +G G+ C A+ C
Sbjct: 662 CPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTC 721
Query: 377 ADCGSGHCDFQSGRCLCSPGVHGPHC----NVTCPPG--LHGADC-----AQACSCHED- 424
++ G+ + + RC C PG G C N +C P ++G C + +C C +
Sbjct: 722 SNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGW 781
Query: 425 ---TCDPVTGACH 434
TC T C+
Sbjct: 782 EGRTCTHNTNDCN 794
Score = 100 bits (250), Expect = 4e-21
Identities = 104/375 (27%), Positives = 133/375 (35%), Gaps = 74/375 (19%)
Query: 99 RCRHGYFGANCDTKC-PRQ-------------------FWGPDCKE-LC--SCH-PHGQC 134
RC Y+ A C+ C PR + G +CKE +C C+ HG C
Sbjct: 197 RCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGC 256
Query: 135 EDVTGQCTCHARRWGARCEHACQ---CQHGTCHPRSGACRCEPGWWGAQC-ASACYCSAT 190
V G+C C G C+ C HG+C C CE W G C YC +
Sbjct: 257 -TVPGECRCSYGWQGRFCDECVPYPGCVHGSC-VEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 191 SRC---------DPQTGACLCHAGWWGRSCNN-QCACNSSPCEQQSGRCQCRERTFGARC 240
C +P C C G+ GR+C + AC S+PC C E G C
Sbjct: 315 HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGG---SCHEVPSGFEC 371
Query: 241 DRYCQCFRGRCHPVDGTCACEPGYRGKYCREP-------CPAGFYGLGCRRRCGQCKGQQ 293
C CA P G C + CP + G C+ +C+G +
Sbjct: 372 HCPSGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEG-K 430
Query: 294 PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAG 353
PC A +C+ G CD C G+ G C CR C H G C G
Sbjct: 431 PCLNA----FSCKNLIGGYYCD--CIPGWKGINCHINVNDCRG--QCQH-GGTCKDLVNG 481
Query: 354 WIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGA 413
+ + C G G C +C S C SG LC G HC+ CP G G
Sbjct: 482 Y-----QCVCPRGFGGRHCELERDECASSPC--HSGG-LCEDLADGFHCH--CPQGFSG- 530
Query: 414 DCAQACSCHEDTCDP 428
C D C+P
Sbjct: 531 ---PLCEVDVDLCEP 542
Score = 96.3 bits (238), Expect = 1e-19
Identities = 100/385 (25%), Positives = 131/385 (34%), Gaps = 107/385 (27%)
Query: 37 LPDTVAPQELNPRGRNVCRAPGSQVPTCCAGW-----RQQGDECGIAVCEGNSTCSENEV 91
+P T A P GR V + G+ C +G+ + D+C C TC +
Sbjct: 597 MPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVD 656
Query: 92 CVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQC---------- 141
R C C G+ G CDT DC CH G+C D+
Sbjct: 657 AFR---CFCPSGWEGELCDTN------PNDCLP-DPCHSRGRCYDLVNDFYCACDDGWKG 706
Query: 142 -TCHARRWGARCEHACQCQHGTCHPRSGA--CRCEPGWWGAQCASA---------CYCSA 189
TCH+R + +C+ GTC+ C C PGW G+ CA A C
Sbjct: 707 KTCHSREF--QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 764
Query: 190 TSRCDPQTGACLCHAGWWGRSC-NNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFR 248
T + +C+C GW GR+C +N CN PC G C
Sbjct: 765 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPC-YNGGIC------------------- 804
Query: 249 GRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPG 308
VDG + R C GF G CR +C+ PC TC
Sbjct: 805 -----VDGV---------NWFRCECAPGFAGPDCRINIDECQ-SSPCAYG----ATCVDE 845
Query: 309 WNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRC---------NAGWIGDRC 359
NG +C CPP R G C V G C + W+ D
Sbjct: 846 INGYRCS---------------CPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCN 890
Query: 360 ETKCSNGTYGEDCAFVCADCGSGHC 384
+C +G DC+ V CG C
Sbjct: 891 SCRCLDGR--RDCSKVW--CGWKPC 911
Score = 67.0 bits (162), Expect = 7e-11
Identities = 67/285 (23%), Positives = 96/285 (33%), Gaps = 82/285 (28%)
Query: 228 RCQCRERTFGARCDRYC---------------------------QCFRGRCH-------- 252
R +C E + A C+++C +C C
Sbjct: 195 RVRCDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHG 254
Query: 253 --PVDGTCACEPGYRGKYCRE------------------PCPAGFYGLGCRRRCGQCKGQ 292
V G C C G++G++C E C + GL C + C
Sbjct: 255 GCTVPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSH 314
Query: 293 QPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGC---SHRCP--PCRDGHACNHV-TGK 346
PCT G C+ EP + +C C G+ G C H C PC +G +C+ V +G
Sbjct: 315 HPCTNG-GTCINAEP--DQYRC--TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGF 369
Query: 347 CTRCNAGWIGDRCETKCSNGTYGEDCAF-VCADCGSGHCDFQSGRCLCSPGVHGPHCNVT 405
C +GW G C ++CA CA G+ C+C G C +
Sbjct: 370 ECHCPSGWSGPTCALDI------DECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLD 423
Query: 406 CPPGLHGADCAQACSCHE----DTCDPVTG----ACHLETNQRKG 442
G C A SC CD + G CH+ N +G
Sbjct: 424 ANE-CEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRG 467
>gi|169790825 odz, odd Oz/ten-m homolog 4 [Homo sapiens]
Length = 2769
Score = 117 bits (294), Expect = 4e-26
Identities = 87/281 (30%), Positives = 110/281 (39%), Gaps = 65/281 (23%)
Query: 72 GDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPH 131
G +CG A C CS N ++ G C C G+ GA CD + C ++ +C H
Sbjct: 589 GPDCGRASCP--VLCSGNGQYMK-GRCLCHSGWKGAECDVPTNQ------CIDV-ACSNH 638
Query: 132 GQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRS----GACRCEPGWWGAQC---ASA 184
G C +TG C C+ G CE C TC R G C C GW G C +
Sbjct: 639 GTC--ITGTCICNPGYKGESCEEV-DCMDPTCSGRGVCVRGECHCSVGWGGTNCETPRAT 695
Query: 185 C--YCSATSRCDPQTGACLCHAGWWGRSCNNQ-CACN---SSPCEQQSGRCQCRERTFGA 238
C CS P TG C C W G C+ + CA + C G C+C + GA
Sbjct: 696 CLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAADCGGHGVC--VGGTCRCEDGWMGA 753
Query: 239 RCDRYCQCFRGRCHP--------VDGTCACEPGYRGKYC----------REPCPAGFYGL 280
CD+ CHP DG C C PG+ G++C +E CP
Sbjct: 754 ACDQRA------CHPRCAEHGTCRDGKCECSPGWNGEHCTIAHYLDRVVKEGCP------ 801
Query: 281 GCRRRCGQCKGQQPCTV-AEGRCLTCEPGWNGTKCDQPCAT 320
G C G CT+ G C+ GW G CD T
Sbjct: 802 ------GLCNGNGRCTLDLNGWHCVCQLGWRGAGCDTSMET 836
Score = 102 bits (255), Expect = 1e-21
Identities = 89/305 (29%), Positives = 113/305 (37%), Gaps = 66/305 (21%)
Query: 127 SCHPHGQCEDVTGQCTCHARRWGARCEHACQCQ---HGTCHPRSGACRCEPGWWGAQC-- 181
+C+ +G C ++G C C G C A C G G C C GW GA+C
Sbjct: 569 NCYGNGDC--ISGTCHCFLGFLGPDCGRA-SCPVLCSGNGQYMKGRCLCHSGWKGAECDV 625
Query: 182 -ASACY---CSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQS----GRCQCRE 233
+ C CS C TG C+C+ G+ G SC + C C + G C C
Sbjct: 626 PTNQCIDVACSNHGTC--ITGTCICNPGYKGESC-EEVDCMDPTCSGRGVCVRGECHCSV 682
Query: 234 RTFGARCDR-----YCQCF-RGRCHPVDGTCACEPGYRGKYCR-EPCPAGFYGLGCRRRC 286
G C+ QC G P G C+C+P + G C E C A
Sbjct: 683 GWGGTNCETPRATCLDQCSGHGTFLPDTGLCSCDPSWTGHDCSIEICAA----------- 731
Query: 287 GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCP---PCRDGHACNHV 343
C G C G CE GW G CDQ C RC CRD
Sbjct: 732 -DCGGHGVCV---GGTCRCEDGWMGAACDQ--------RACHPRCAEHGTCRD------- 772
Query: 344 TGKCTRCNAGWIGDRCE-TKCSNGTYGEDCAFVCADCGSGHC--DFQSGRCLCSPGVHGP 400
GKC C+ GW G+ C + E C +C G+G C D C+C G G
Sbjct: 773 -GKC-ECSPGWNGEHCTIAHYLDRVVKEGCPGLCN--GNGRCTLDLNGWHCVCQLGWRGA 828
Query: 401 HCNVT 405
C+ +
Sbjct: 829 GCDTS 833
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 116 bits (290), Expect = 1e-25
Identities = 112/397 (28%), Positives = 146/397 (36%), Gaps = 106/397 (26%)
Query: 50 GRNVCRAPGSQVPTCCAGWRQQGDECGIAVCEGNSTCSE-NEVCVRPGECRCRHGYFGAN 108
G VC+ G+ +C GW G+ C +C S C E N C +P EC CR G+ G
Sbjct: 196 GHYVCQPDGNL--SCLPGWT--GEYCQQPICL--SGCHEQNGYCSKPAECLCRPGWQGRL 249
Query: 109 CDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGA--------RCEHACQCQH 160
C+ P C+ HG C QCTC WG C H C++
Sbjct: 250 CNECIPHN----GCR-------HGTC-STPWQCTCD-EGWGGLFCDQDLNYCTHHSPCKN 296
Query: 161 G-TCH---PRSGACRCEPGWWGAQC---ASAC---YCSATSRCDPQTGA--CLCHAGWWG 208
G TC RS C C PG+ G C S C C C Q CLC G++G
Sbjct: 297 GATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYG 356
Query: 209 RSC-NNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGK 267
C ++ +C SPC CRER GA + C C P + G
Sbjct: 357 LHCEHSTLSCADSPCFNGG---SCRERNQGA----------------NYACECPPNFTGS 397
Query: 268 YCRE--------PCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCA 319
C + PC G GQC + P R C PG+ GT C+
Sbjct: 398 NCEKKVDRCTSNPCANG----------GQCLNRGP-----SRMCRCRPGFTGTYCE---- 438
Query: 320 TGFYGEGCSHRCPPCRDGHACNHV-TGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCAD 378
+ C+ PC G C+ + G C AG+ G RCE + S F A
Sbjct: 439 --LHVSDCARN--PCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRAT 494
Query: 379 CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADC 415
C + D + +C+ CP G G+ C
Sbjct: 495 C---YTDLSTDTFVCN-----------CPYGFVGSRC 517
Score = 101 bits (251), Expect = 3e-21
Identities = 92/321 (28%), Positives = 111/321 (34%), Gaps = 77/321 (23%)
Query: 143 CHARRWGARCEHACQCQ-----HGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQT 197
C +G C C+ + H C P G C PGW G C S C Q
Sbjct: 175 CSDNYYGDNCSRLCKKRNDHFGHYVCQP-DGNLSCLPGWTGEYCQQPICLSG---CHEQN 230
Query: 198 G------ACLCHAGWWGRSCNNQC----ACNSSPCEQQSGRCQCRERTFGARCDR---YC 244
G CLC GW GR CN +C C C +C C E G CD+ YC
Sbjct: 231 GYCSKPAECLCRPGWQGRLCN-ECIPHNGCRHGTCSTP-WQCTCDEGWGGLFCDQDLNYC 288
Query: 245 Q----CFRGRCHPVDG----TCACEPGYRGKYCR--------EPCPAGFYGLGCRRRCGQ 288
C G G TC C PGY G C PC G G
Sbjct: 289 THHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNG----------GS 338
Query: 289 CKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHAC---NHVTG 345
CK Q+ +G C PG+ G C+ + C+ PC +G +C N
Sbjct: 339 CKDQE-----DGYHCLCPPGYYGLHCEHSTLS------CADS--PCFNGGSCRERNQGAN 385
Query: 346 KCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVT 405
C + G CE K T CA+ G S C C PG G +C
Sbjct: 386 YACECPPNFTGSNCEKKVDRCTSNP-----CANGGQCLNRGPSRMCRCRPGFTGTYCE-- 438
Query: 406 CPPGLHGADCAQACSCHEDTC 426
LH +DCA+ H TC
Sbjct: 439 ----LHVSDCARNPCAHGGTC 455
Score = 84.3 bits (207), Expect = 4e-16
Identities = 68/242 (28%), Positives = 94/242 (38%), Gaps = 67/242 (27%)
Query: 226 SGRCQCRERTFGARCDRYCQCFRGR-----CHPVDGTCACEPGYRGKYCREP-CPAGFYG 279
S R C + +G C R C+ C P DG +C PG+ G+YC++P C +G +
Sbjct: 170 SYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQP-DGNLSCLPGWTGEYCQQPICLSGCHE 228
Query: 280 LG----------CR-----RRCGQCKGQQPCTVAEGRC-----LTCEPGWNGTKCDQPCA 319
CR R C +C C G C TC+ GW G CDQ
Sbjct: 229 QNGYCSKPAECLCRPGWQGRLCNECIPHNGC--RHGTCSTPWQCTCDEGWGGLFCDQDL- 285
Query: 320 TGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADC 379
C+H PC++G C++ + C C G G DC ++C
Sbjct: 286 -----NYCTHH-SPCKNGATCSNSGQRSYTCT-----------CRPGYTGVDCELELSEC 328
Query: 380 GSGHC-------DFQSG-RCLCSPGVHGPHC---NVTC--PPGLHGADCAQ-------AC 419
S C D + G CLC PG +G HC ++C P +G C + AC
Sbjct: 329 DSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYAC 388
Query: 420 SC 421
C
Sbjct: 389 EC 390
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 114 bits (285), Expect = 4e-25
Identities = 119/465 (25%), Positives = 154/465 (33%), Gaps = 143/465 (30%)
Query: 98 CRCRHGYFGANCDTKCPRQF------WGPDCKELCSCHPHGQCEDVTGQC-TCHARRWGA 150
C C GY G +C++ + +G C+ C CH H +V G C C G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQP-CECHGHAAECNVHGVCIACAHNTTGV 767
Query: 151 RCEHA------------------CQCQ--------HGTCHPRSG---ACR-CEPGWWGAQ 180
CE C C TCH G C C PG+ GA
Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAW 827
Query: 181 CASA-----------------CYCSAT------SRCDPQTGACL-------------CHA 204
C C CS CD TG CL C
Sbjct: 828 CERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCAD 887
Query: 205 GWWG-----RSCNNQCACN-----SSPCEQQSGRCQCRERTFGARCDRYCQCFRGR---- 250
G++G ++C C C+ S+ C ++G C C+ G +CD QC G
Sbjct: 888 GFYGDAVTAKNCR-ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCD---QCLHGYYGLD 943
Query: 251 ----CHPV--------------DGTCACEPGYRGKYCREPCPAGFYGL--GCRRRCGQCK 290
C P +G C C PG GK C + C GFY G C
Sbjct: 944 SGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTPCDCPH 1002
Query: 291 GQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDG------HACNHVT 344
Q C G C+ C P G KC++ C G +G C C H C+ VT
Sbjct: 1003 TQNTCDPETGECV-CPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVT 1060
Query: 345 GKCTRCNAGWIGDRCETKCS----------------NGTYGEDCAFVCADCGSGHCDFQS 388
G C +C + + G C+ +CS GT G+ C CG C ++
Sbjct: 1061 GHC-QCKSKFGGRACD-QCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCG---CVEET 1115
Query: 389 GRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGAC 433
G C C V GP CN C G C C ++ C
Sbjct: 1116 GACPCKENVFGPQCN-ECREGTFALRADNPLGCSPCFCSGLSHLC 1159
Score = 84.7 bits (208), Expect = 3e-16
Identities = 66/244 (27%), Positives = 87/244 (35%), Gaps = 62/244 (25%)
Query: 58 GSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQF 117
G Q C G+ G C + S ++ C G+C C G G CD +C F
Sbjct: 929 GQQCDQCLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGF 987
Query: 118 WG---PDCKELCSC-HPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCE 173
+ C C C H C+ TG+C C G +CE CE
Sbjct: 988 YAYQDGSCTP-CDCPHTQNTCDPETGECVCPPHTQGVKCE-----------------ECE 1029
Query: 174 PGWWGAQC---ASACYCSATS----RCDPQTGACLCHAGWWGRSCNNQC----------- 215
G WG AC CS RCD TG C C + + GR+C +QC
Sbjct: 1030 DGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRAC-DQCSLGYRDFPDCV 1088
Query: 216 ------------ACNSSP----CEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTC 258
ACN C +++G C C+E FG +C+ +C G D
Sbjct: 1089 PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCN---ECREGTFALRADNPL 1145
Query: 259 ACEP 262
C P
Sbjct: 1146 GCSP 1149
Score = 63.5 bits (153), Expect = 8e-10
Identities = 62/213 (29%), Positives = 81/213 (38%), Gaps = 58/213 (27%)
Query: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQP----------------CTVAEGR 301
C C PG G C++ P G + G +G +P C G+
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRG---KLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGK 1418
Query: 302 CLTCEPGWNGTKCDQPCATGFYGE--GCSHRCPPCRDGHACNHVTG-------------- 345
CL C G CD C +G+YG+ G + C C AC H
Sbjct: 1419 CLNCGDNTAGDHCDV-CTSGYYGKVTGSASDCALC----ACPHSPPASFSPTCVLEGDHD 1473
Query: 346 -KCTRCNAGWIGDRCETKCSNGTYG--EDCAFVCADC-----GSGH--CDFQSGRCLCSP 395
+C C G+ G CE +CS+ YG + C C GS H CD SG+C+C
Sbjct: 1474 FRCDACLLGYEGKHCE-RCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRL 1532
Query: 396 GVHGPHCNVTCPPG--LHGADCAQACSCHEDTC 426
G G C+ C P L DC SC +D C
Sbjct: 1533 GASGLRCD-ECEPRHILMETDCV---SC-DDEC 1560
Score = 60.5 bits (145), Expect = 7e-09
Identities = 66/252 (26%), Positives = 94/252 (37%), Gaps = 54/252 (21%)
Query: 76 GIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCP---RQFWGP------DCKELC 126
G+ +C G+++ + + +C+C H G +C+ CP +Q W P + E C
Sbjct: 268 GMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEAC 327
Query: 127 SCHPHGQ-C---EDVTGQ----CTCHARRWGARCEHACQCQHG-TCHPRSGACRCEPGWW 177
+CH + C E V Q T R G C + Q G C C G++
Sbjct: 328 NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE------TCIDGYY 381
Query: 178 GAQCASACYCSATSR---CDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRER 234
S Y R CDP G C + +Q G+C C+E
Sbjct: 382 RPHKVSP-YEDEPCRPCNCDP--------VGSLSSVCIKDDLHSDLHNGKQPGQCPCKEG 432
Query: 235 TFGARCDR-------YCQCFRGRCHPV--------DGTCACEPGYRGKYCREPCPAGFYG 279
G +CDR Y C C+PV G C C+ GK C + C GFY
Sbjct: 433 YTGEKCDRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKAC-DRCKPGFYN 491
Query: 280 LGCR--RRCGQC 289
L + R C +C
Sbjct: 492 LKEKNPRGCSEC 503
Score = 54.3 bits (129), Expect = 5e-07
Identities = 65/266 (24%), Positives = 96/266 (36%), Gaps = 60/266 (22%)
Query: 210 SCNNQCAC----NSSPCEQQSGR--CQCRERTFGARCDRYC-----QCFRGRCHPVDGTC 258
S C C +S P ++ + + CQC T G C+R C Q +R TC
Sbjct: 265 SVGGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTC 324
Query: 259 -ACEPGYRGKYCREPCPAGFYGLGCRRR------CGQCKGQQPCTVAEGRCLTCEPGWNG 311
AC + K C +Y ++ GQ +G G C+ C G
Sbjct: 325 EACNCHNKAKDC-------YYDESVAKQKKSLNTAGQFRG-------GGVCINCLQNTMG 370
Query: 312 TKCDQPCATGFY--GEGCSHRCPPCR-----------------DGHACNH---VTGKCTR 349
C + C G+Y + + PCR D H+ H G+C
Sbjct: 371 INC-ETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCP- 428
Query: 350 CNAGWIGDRCETKCSNG--TYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCP 407
C G+ G++C+ +C G Y + C GS + +G C+C V G C+ C
Sbjct: 429 CKEGYTGEKCD-RCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD-RCK 486
Query: 408 PGLHGADCAQACSCHEDTCDPVTGAC 433
PG + C E C V+ C
Sbjct: 487 PGFYNLKEKNPRGCSECFCFGVSDVC 512
Score = 52.8 bits (125), Expect = 1e-06
Identities = 44/189 (23%), Positives = 63/189 (33%), Gaps = 39/189 (20%)
Query: 58 GSQVPTCCAG-WRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
G + C G + Q C C + E GEC C G C+ +C
Sbjct: 977 GKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPET----GECVCPPHTQGVKCE-ECEDG 1031
Query: 117 FWGPDCK---ELCSCH----PHGQCEDVTGQCTCHARRWGARCEH--------------- 154
WG D + + C+C H +C+ VTG C C ++ G C+
Sbjct: 1032 HWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCD 1091
Query: 155 ---------ACQCQHGTCH--PRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCH 203
AC + G C +GAC C+ +G QC + R D G C
Sbjct: 1092 CDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNECREGTFALRADNPLGCSPCF 1151
Query: 204 AGWWGRSCN 212
C+
Sbjct: 1152 CSGLSHLCS 1160
Score = 52.0 bits (123), Expect = 2e-06
Identities = 33/122 (27%), Positives = 54/122 (44%), Gaps = 22/122 (18%)
Query: 58 GSQVPTCCAGWRQQ----GDECGIAVCEGNSTCSENEVCVRPGE----C-RCRHGYFGAN 108
G C +G+ + +C + C + S + CV G+ C C GY G +
Sbjct: 1428 GDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKH 1487
Query: 109 CDTKCPRQFWGP------DCKELCSCHPHGQ----CEDVTGQCTCHARRWGARCEHACQC 158
C+ +C ++G C++ C C+PHG C+ +GQC C G RC+ C+
Sbjct: 1488 CE-RCSSSYYGNPQTPGGSCQK-CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
Query: 159 QH 160
+H
Sbjct: 1545 RH 1546
Score = 45.1 bits (105), Expect = 3e-04
Identities = 53/203 (26%), Positives = 67/203 (33%), Gaps = 63/203 (31%)
Query: 88 ENEVCVRPGECRCRHGYFGANCDTKCPRQFWGP--------------DCKELCSCHPHGQ 133
E EV C C G G +C P G C CSC+ H
Sbjct: 1352 EEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVP-CSCNNHSD 1410
Query: 134 -CEDVTGQC-TCHARRWGARCEHA-----------------CQCQHGTCHPRSGAC---- 170
C+ TG+C C G C+ C C H S C
Sbjct: 1411 TCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEG 1470
Query: 171 ----RCEP---GWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNS---- 219
RC+ G+ G C CS++ +PQT G SC +C CN
Sbjct: 1471 DHDFRCDACLLGYEGKHCER---CSSSYYGNPQTP---------GGSCQ-KCDCNPHGSV 1517
Query: 220 -SPCEQQSGRCQCRERTFGARCD 241
C++ SG+C CR G RCD
Sbjct: 1518 HGDCDRTSGQCVCRLGASGLRCD 1540
Score = 42.0 bits (97), Expect = 0.002
Identities = 45/195 (23%), Positives = 60/195 (30%), Gaps = 55/195 (28%)
Query: 129 HPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQCASACYCS 188
HP + + C C G C+ H P +G+ R P A C +
Sbjct: 1350 HPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLP-AGSDR-GPRPLVAPCVPCSCNN 1407
Query: 189 ATSRCDPQTGACL-------------CHAGWWGRSCNNQ-----CACNSSP--------- 221
+ CDP TG CL C +G++G+ + CAC SP
Sbjct: 1408 HSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCACPHSPPASFSPTCV 1467
Query: 222 --------------------CEQQSGRCQCRERTFGARCDRYCQC-----FRGRCHPVDG 256
CE+ S +T G C + C C G C G
Sbjct: 1468 LEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQK-CDCNPHGSVHGDCDRTSG 1526
Query: 257 TCACEPGYRGKYCRE 271
C C G G C E
Sbjct: 1527 QCVCRLGASGLRCDE 1541
Score = 39.7 bits (91), Expect = 0.012
Identities = 24/59 (40%), Positives = 26/59 (44%), Gaps = 17/59 (28%)
Query: 391 CLCSPGVHGPHCNVTCPPGLH------GADCAQA--------CSC--HEDTCDPVTGAC 433
C+C PG G C C PG H G+D CSC H DTCDP TG C
Sbjct: 1362 CVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKC 1419
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 113 bits (283), Expect = 7e-25
Identities = 120/415 (28%), Positives = 145/415 (34%), Gaps = 58/415 (13%)
Query: 56 APGSQVPTCCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDT---- 111
A G Q P C R C + C +TC ++ R C C GY G +C T
Sbjct: 794 AMGFQGPRCEGKLRPS---CADSPCRNRATCQDSPQGPR---CLCPTGYTGGSCQTLMDL 847
Query: 112 ----KCPRQFW----GPDCKELCSCHPHGQ-CEDVTGQCTCHARRWGARCEHACQCQHGT 162
CPR GP LC G C C A G C G
Sbjct: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCH-NGGL 906
Query: 163 CHPRSGA--CRCEPGWWGAQC--------ASACYCSATSRCDPQTGACLCHAGWWGRSCN 212
C + C C PG+ G+ C + C AT P C C G+ G++C+
Sbjct: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS 966
Query: 213 NQC-ACNSSPCEQQSG--------RCQCRERTFGARCDRYC-QCFRGRCHPVDGTCACEP 262
+ AC S PC C C G RC+ +C CHP GT AC
Sbjct: 967 KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT-GTAACHS 1025
Query: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF 322
YC+ C G G C C Q PC G C G C C GF
Sbjct: 1026 LANAFYCQ--CLPGHTGQWCEVEIDPCHSQ-PCFHG-GTCEATAGSPLGFICH--CPKGF 1079
Query: 323 YGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCAD--CG 380
G CSHR P C H C+H G C RC C +G G DC A CG
Sbjct: 1080 EGPTCSHRAPSC-GFHHCHH-GGLCLPSPKPGFPPRCA--CLSGYGGPDCLTPPAPKGCG 1135
Query: 381 SGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQ--ACSCHEDTCDPVTGAC 433
+G C + G+ GP +CP G C + A C + D GAC
Sbjct: 1136 PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGD---GAC 1187
Score = 113 bits (282), Expect = 9e-25
Identities = 135/549 (24%), Positives = 178/549 (32%), Gaps = 167/549 (30%)
Query: 16 GAGGPPSPLLPSLLLLLLLWM--------LPDTVAPQELNPRGRNVCRAPGSQVPTCCAG 67
G PSPL PS L L L D P + RGR +A G +C G
Sbjct: 89 GLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG 148
Query: 68 WRQQGDECGIAVCEGNSTCSENEVCVRPG---ECRCRHGYFGANCDTKCPRQFWGPD-CK 123
W G++C + + C VC+ +C C G+ G C+ F P C
Sbjct: 149 WT--GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
Query: 124 ELCSCHPHGQCEDVTG--QCTCHARRWGARCEHACQCQHGTCHPRSGA------------ 169
+ SCH + G QC C + G RCE + G C PR +
Sbjct: 207 KGTSCH------NTLGSFQCLCPVGQEGPRCE----LRAGPCPPRGCSNGGTCQLMPEKD 256
Query: 170 -----CRCEPGWWGAQC--------ASACYCSATSRCDPQTGACLCHAGWWGRSCN---N 213
C C PG+ G C + C T + T CLC W G C+ +
Sbjct: 257 STFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVD 316
Query: 214 QCACNSSPCEQQSGRCQCRERTFGARC----------DRYCQCFRGRCHP----VDG--- 256
+C P + G CQ +F C + C C P +D
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS 376
Query: 257 -TCACEPGYRGKYCR-------EPCPA-------------------GFYGLGCRRRCGQC 289
+C C PG G C +PC G+ G C + +C
Sbjct: 377 FSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 290 ----KGQQPCTVAEGRCLT--------CEPGWNGTKCD--------QPCATGFYGEGCSH 329
+G PC G CL C PG+ G++C+ QPC G C
Sbjct: 437 LMAQQGPSPCEHG-GSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPG---STCLD 492
Query: 330 R-------CPPCRDGHACNHVTGKCTR-------------------CNAGWIGDRCETKC 363
CPP +G C T +C C G+ G RCE
Sbjct: 493 LLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI 552
Query: 364 SNGTYGEDC-AFVCADCGSGHCDFQSG--RCLCSPGVHGPHCNV--------TCPPGLHG 412
++C + CA+ G C Q G C C PG GP C CP G
Sbjct: 553 ------DECRSSPCAN--GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
Query: 413 ADCAQACSC 421
D A C
Sbjct: 605 LDLPGAFFC 613
Score = 110 bits (275), Expect = 6e-24
Identities = 119/441 (26%), Positives = 151/441 (34%), Gaps = 105/441 (23%)
Query: 76 GIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTK----------------------- 112
G A E N TC C R C C G+ G C+ +
Sbjct: 657 GCAPPEDNCTCHHGH-CQR-SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYN 714
Query: 113 --CPRQFWGPDC-KELCSCHPH-----GQCEDVTG--QCTCHARRWGARCEHACQC---- 158
CP + GP C +E+ +CH G C G CTC G +C+ +
Sbjct: 715 CTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA 774
Query: 159 ---QHGTCHPRSG--ACRCEPGWWGAQCA---------SACYCSATSRCDPQTGACLCHA 204
GTC R G +C C G+ G +C S C AT + PQ CLC
Sbjct: 775 PCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPT 834
Query: 205 GWWGRSCNN-QCACNSSPCEQQSG--------RCQCRERTFGARCD---RYCQ------- 245
G+ G SC C PC + S C C + G C+ CQ
Sbjct: 835 GYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
Query: 246 -CFRGRCHPVDGTCA-CEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCL 303
CH G C P Y +C CP GF G C+ C+ +PC
Sbjct: 895 IDVSSLCHN-GGLCVDSGPSY---FCH--CPPGFQGSLCQDHVNPCE-SRPCQ----NGA 943
Query: 304 TCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCT--------RCNAGWI 355
TC +G C CA G+ G+ CS C+ NH G CT C G++
Sbjct: 944 TCMAQPSGYLCQ--CAPGYDGQNCSKELDACQSQPCHNH--GTCTPKPGGFHCACPPGFV 999
Query: 356 GDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGR--CLCSPGVHGPHCNVTCPPGLHGA 413
G RCE G E C G+ C + C C PG G C V P H
Sbjct: 1000 GLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP-CHSQ 1053
Query: 414 DCAQACSCHEDTCDPVTGACH 434
C +C P+ CH
Sbjct: 1054 PCFHGGTCEATAGSPLGFICH 1074
Score = 108 bits (270), Expect = 2e-23
Identities = 128/476 (26%), Positives = 167/476 (35%), Gaps = 133/476 (27%)
Query: 26 PSLLLLLLLWMLPDTVAPQELNPRGRNVCRAPGSQVPTCCAGWRQQGDECGI--AVCEGN 83
PSLLLLLLL +L C + R +G CG C
Sbjct: 4 PSLLLLLLLLLL-------------------------LCVSVVRPRGLLCGSFPEPCANG 38
Query: 84 STCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTGQ--- 140
TC + + G C+C G+ G C QF P C+ C G C+ +
Sbjct: 39 GTCLS--LSLGQGTCQCAPGFLGETC------QFPDP-CQNAQLCQNGGSCQALLPAPLG 89
Query: 141 -------------CTCHARRWGARCEHACQ--------CQHGTCHPRSGA---CRCEPGW 176
CTC G RC+ + + G CH ++ C C PGW
Sbjct: 90 LPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW 149
Query: 177 WGAQCASACYCSATSRCD--------PQTGACLCHAGWWGRSCN---NQCACNSSPCEQ- 224
G QC +CSA + PQ C C G+ G +C N+C + PC +
Sbjct: 150 TGEQCQLRDFCSANPCVNGGVCLATYPQI-QCHCPPGFEGHACERDVNECFQDPGPCPKG 208
Query: 225 -------QSGRCQCRERTFGARCDRYCQCFRGRCHP----VDGTCACEPGYRGKYCREPC 273
S +C C G RC+ G C P GTC P + C
Sbjct: 209 TSCHNTLGSFQCLCPVGQEGPRCELRA----GPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
Query: 274 PAGFYGLGCRRRCGQCKGQQPC----TVAEG----RCLTCEPGWNGTKCDQPCATGFYGE 325
P GF G C C Q C T +G CL C W G C + +
Sbjct: 265 PPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGLDTYTCL-CPETWTGWDCSEDV------D 316
Query: 326 GCSHRCPP-CRDGHACNHVTGK--CTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG 382
C + PP CR+G C + G C C +GW G CE +DC + A C G
Sbjct: 317 ECETQGPPHCRNGGTCQNSAGSFHCV-CVSGWGGTSCEENL------DDC--IAATCAPG 367
Query: 383 HCDFQ---SGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED---TCDPVTGA 432
S CLC PG G C H D + CH D + +P+TG+
Sbjct: 368 STCIDRVGSFSCLCPPGRTGLLC--------HLEDMCLSQPCHGDAQCSTNPLTGS 415
Score = 75.5 bits (184), Expect = 2e-13
Identities = 105/408 (25%), Positives = 141/408 (34%), Gaps = 107/408 (26%)
Query: 39 DTVAPQELNP--RGRNVCRAPGSQVPTCCAGWRQQG-----DECGIAVCEGNSTCSENEV 91
D V P E P G P + C G+ Q D C C + TC+
Sbjct: 929 DHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTP--- 985
Query: 92 CVRPG--ECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQ--CEDVTGQ--CTCHA 145
+PG C C G+ G C+ P CHP G C + C C
Sbjct: 986 --KPGGFHCACPPGFVGLRCEGDVDECLDQP-------CHPTGTAACHSLANAFYCQCLP 1036
Query: 146 RRWGARCE------HACQCQHG-TCHPRSGA-----CRCEPGWWGAQC---ASAC---YC 187
G CE H+ C HG TC +G+ C C G+ G C A +C +C
Sbjct: 1037 GHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHC 1096
Query: 188 SATSRC--DPQTG---ACLCHAGWWGRSC-----------NNQCACNSSPCEQQSG---- 227
C P+ G C C +G+ G C + C N S C + +G
Sbjct: 1097 HHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS-CSETTGLGGP 1155
Query: 228 --RCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPG-------YRGKYCREPCPAGFY 278
RC C + G RC + +G C G AC+ G + G C P +
Sbjct: 1156 GFRCSCPHSSPGPRCQK--PGAKG-CEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWK 1212
Query: 279 GLGCRRRC------GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCP 332
G RC GQC Q C E CL ++G C+ P A C
Sbjct: 1213 GCPSHSRCWLLFRDGQCHPQ--CDSEE--CL-----FDGYDCETPPA-----------CT 1252
Query: 333 PCRDGHACNHV-TGKCTR-CNA---GWIGDRCETKCSNGTYGEDCAFV 375
P D + +H G C + CN GW G C + + +G A +
Sbjct: 1253 PAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALL 1300
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 112 bits (280), Expect = 1e-24
Identities = 114/365 (31%), Positives = 136/365 (37%), Gaps = 88/365 (24%)
Query: 126 CSCHPHG-QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEP-----GWWGA 179
C CH H +C G + + C CQH T P RC P W A
Sbjct: 250 CFCHGHADRCAPKPGASAGPST--AVQVHDVCVCQHNTAGPNCE--RCAPFYNNRPWRPA 305
Query: 180 QCASACYCSATSRCDPQTGACLCH---------AGWWGRSCNNQCACNSSPCEQQSGRCQ 230
+ A C RCD + CH G +G C+N C + RCQ
Sbjct: 306 EGQDAHECQ---RCDCNGHSETCHFDPAVFAASQGAYGGVCDN---CRDHTEGKNCERCQ 359
Query: 231 C---RERTFGARCDRYC---QCFR------GRCHPVDGTCACEPGYRGKYCREPCPAGFY 278
R R GA C +C C PV G C C+ +G+ C + C GF
Sbjct: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFT 418
Query: 279 GL------GCRRRCGQCKGQQ---PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH 329
GL GC R G + PC GRCL C P G KCDQ CA +
Sbjct: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQ-CAPYHWKLASGQ 476
Query: 330 RCPPCR-DGH-----ACNHVTGKCTRCNAGWIGDRCET----KCSNGTYGEDCAFVCADC 379
C PC D H CN TG+C C G+ G C +C + TYG D A C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYG-DVATGCRAC 534
Query: 380 --------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCD--PV 429
G G CD SGRCLC PG+ GP C+ C C+ PV
Sbjct: 535 DCDFRGTEGPG-CDKASGRCLCRPGLTGPRCD----------------QCQRGYCNRYPV 577
Query: 430 TGACH 434
ACH
Sbjct: 578 CVACH 582
Score = 93.2 bits (230), Expect = 9e-19
Identities = 86/321 (26%), Positives = 115/321 (35%), Gaps = 93/321 (28%)
Query: 98 CRCRHGYFGANCDTKCP-------RQFWGPDCKEL--CSCHPHGQCEDVTGQCTCH---A 145
C C+H G NC+ P R G D E C C+ H + TCH A
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSE--------TCHFDPA 330
Query: 146 RRWGARCEHACQCQHGTCHPRSGAC-RCE--------PGWWGAQCASACYCSAT-----S 191
++ + C + H C RC+ PG + +C C +
Sbjct: 331 VFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA 390
Query: 192 RCDPQTGACLCHAGWWGRSCN-----------------NQCACN------SSPCEQQSGR 228
CDP TG C+C G C+ ++C CN PC+++SGR
Sbjct: 391 PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGR 450
Query: 229 CQCRERTFGARCDRY---------------CQC-----FRGRCHPVDGTCACEPGYRGKY 268
C C G +CD+ C C +C+ G C C G+ G
Sbjct: 451 CLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLM 510
Query: 269 CR----EPCPAGFYG---LGCRRRCGQCKGQQ--PCTVAEGRCLTCEPGWNGTKCDQPCA 319
C CP YG GCR +G + C A GRCL C PG G +CDQ C
Sbjct: 511 CSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQ-CQ 568
Query: 320 TGFYGEGCSHRCPPCRDGHAC 340
G+ +R P C H C
Sbjct: 569 RGY-----CNRYPVCVACHPC 584
Score = 81.3 bits (199), Expect = 4e-15
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 95/289 (32%)
Query: 68 WR----QQGDECGIAVCEGNS-TCSENEVCVRP------GEC-RCRHGYFGANCDTKCPR 115
WR Q EC C G+S TC + G C CR G NC+ +C
Sbjct: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE-RCQL 360
Query: 116 QFW-----GPDCKELC---SCHPHGQ-----CEDVTGQCTCHARRWGARCE--------- 153
++ G +E C C P G C+ VTGQC C G RC+
Sbjct: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 154 --------HACQC------QHGTCHPRSGACRCEPGWWGAQC---------------ASA 184
H C C + C SG C C P G +C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 185 CYC----SATSRCDPQTGACLCHAGWWGRSCN----NQC-------------ACNSS--- 220
C C S + +C+ TG C C G+ G C+ QC AC+
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 221 ----PCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265
C++ SGRC CR G RCD QC RG C+ AC P ++
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCD---QCQRGYCNRYPVCVACHPCFQ 586
Score = 68.6 bits (166), Expect = 2e-11
Identities = 82/301 (27%), Positives = 109/301 (36%), Gaps = 73/301 (24%)
Query: 184 ACYCSA-TSRCDPQTGA-------------CLCHAGWWGRSCNNQCA--CNSSPCEQQSG 227
+C+C RC P+ GA C+C G +C +CA N+ P G
Sbjct: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCE-RCAPFYNNRPWRPAEG 307
Query: 228 R----CQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCR 283
+ CQ RCD C CH A G G C + C G C
Sbjct: 308 QDAHECQ--------RCD--CNGHSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCE 356
Query: 284 R-RCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNH 342
R + + ++P + C++CE CD A G C+
Sbjct: 357 RCQLHYFRNRRPGASIQETCISCE-------CDPDGAV---------------PGAPCDP 394
Query: 343 VTGKCTRCNAGWIGDRCETKCSNG----TYGEDCAFVCADC---GSGH---CDFQSGRCL 392
VTG+C C G+RC+ C G TY DC GS CD +SGRCL
Sbjct: 395 VTGQCV-CKEHVQGERCDL-CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Query: 393 CSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDP---VTGACHLETNQRKGVMGAGAL 449
C P V GP C+ P + A C CDP ++ C+ T Q G G L
Sbjct: 453 CLPNVVGPKCDQCAP---YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGL 509
Query: 450 L 450
+
Sbjct: 510 M 510
Score = 51.2 bits (121), Expect = 4e-06
Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 24/142 (16%)
Query: 50 GRNVCRAPGSQVPTC--CAGWRQQ---GDECGIAVCEGNSTCSENEVCVR-PGECRCRHG 103
GR +C P P C CA + + G C C+ +++ S C + G+C CR G
Sbjct: 449 GRCLC-LPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ--CNQFTGQCPCREG 505
Query: 104 YFGANCDT----KCPRQFWG---PDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARC 152
+ G C +CP + +G C+ C C G C+ +G+C C G RC
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 153 EHACQCQHGTCHPRSGACRCEP 174
+ QCQ G C+ C P
Sbjct: 565 D---QCQRGYCNRYPVCVACHP 583
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 112 bits (280), Expect = 1e-24
Identities = 114/365 (31%), Positives = 136/365 (37%), Gaps = 88/365 (24%)
Query: 126 CSCHPHG-QCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEP-----GWWGA 179
C CH H +C G + + C CQH T P RC P W A
Sbjct: 250 CFCHGHADRCAPKPGASAGPST--AVQVHDVCVCQHNTAGPNCE--RCAPFYNNRPWRPA 305
Query: 180 QCASACYCSATSRCDPQTGACLCH---------AGWWGRSCNNQCACNSSPCEQQSGRCQ 230
+ A C RCD + CH G +G C+N C + RCQ
Sbjct: 306 EGQDAHECQ---RCDCNGHSETCHFDPAVFAASQGAYGGVCDN---CRDHTEGKNCERCQ 359
Query: 231 C---RERTFGARCDRYC---QCFR------GRCHPVDGTCACEPGYRGKYCREPCPAGFY 278
R R GA C +C C PV G C C+ +G+ C + C GF
Sbjct: 360 LHYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERC-DLCKPGFT 418
Query: 279 GL------GCRRRCGQCKGQQ---PCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSH 329
GL GC R G + PC GRCL C P G KCDQ CA +
Sbjct: 419 GLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL-CLPNVVGPKCDQ-CAPYHWKLASGQ 476
Query: 330 RCPPCR-DGH-----ACNHVTGKCTRCNAGWIGDRCET----KCSNGTYGEDCAFVCADC 379
C PC D H CN TG+C C G+ G C +C + TYG D A C C
Sbjct: 477 GCEPCACDPHNSLSPQCNQFTGQCP-CREGFGGLMCSAAAIRQCPDRTYG-DVATGCRAC 534
Query: 380 --------GSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCD--PV 429
G G CD SGRCLC PG+ GP C+ C C+ PV
Sbjct: 535 DCDFRGTEGPG-CDKASGRCLCRPGLTGPRCD----------------QCQRGYCNRYPV 577
Query: 430 TGACH 434
ACH
Sbjct: 578 CVACH 582
Score = 93.2 bits (230), Expect = 9e-19
Identities = 86/321 (26%), Positives = 115/321 (35%), Gaps = 93/321 (28%)
Query: 98 CRCRHGYFGANCDTKCP-------RQFWGPDCKEL--CSCHPHGQCEDVTGQCTCH---A 145
C C+H G NC+ P R G D E C C+ H + TCH A
Sbjct: 279 CVCQHNTAGPNCERCAPFYNNRPWRPAEGQDAHECQRCDCNGHSE--------TCHFDPA 330
Query: 146 RRWGARCEHACQCQHGTCHPRSGAC-RCE--------PGWWGAQCASACYCSAT-----S 191
++ + C + H C RC+ PG + +C C +
Sbjct: 331 VFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRRPGASIQETCISCECDPDGAVPGA 390
Query: 192 RCDPQTGACLCHAGWWGRSCN-----------------NQCACN------SSPCEQQSGR 228
CDP TG C+C G C+ ++C CN PC+++SGR
Sbjct: 391 PCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGR 450
Query: 229 CQCRERTFGARCDRY---------------CQC-----FRGRCHPVDGTCACEPGYRGKY 268
C C G +CD+ C C +C+ G C C G+ G
Sbjct: 451 CLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLM 510
Query: 269 CR----EPCPAGFYG---LGCRRRCGQCKGQQ--PCTVAEGRCLTCEPGWNGTKCDQPCA 319
C CP YG GCR +G + C A GRCL C PG G +CDQ C
Sbjct: 511 CSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCL-CRPGLTGPRCDQ-CQ 568
Query: 320 TGFYGEGCSHRCPPCRDGHAC 340
G+ +R P C H C
Sbjct: 569 RGY-----CNRYPVCVACHPC 584
Score = 81.3 bits (199), Expect = 4e-15
Identities = 79/289 (27%), Positives = 101/289 (34%), Gaps = 95/289 (32%)
Query: 68 WR----QQGDECGIAVCEGNS-TCSENEVCVRP------GEC-RCRHGYFGANCDTKCPR 115
WR Q EC C G+S TC + G C CR G NC+ +C
Sbjct: 302 WRPAEGQDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCE-RCQL 360
Query: 116 QFW-----GPDCKELC---SCHPHGQ-----CEDVTGQCTCHARRWGARCE--------- 153
++ G +E C C P G C+ VTGQC C G RC+
Sbjct: 361 HYFRNRRPGASIQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGL 420
Query: 154 --------HACQC------QHGTCHPRSGACRCEPGWWGAQC---------------ASA 184
H C C + C SG C C P G +C
Sbjct: 421 TYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEP 480
Query: 185 CYC----SATSRCDPQTGACLCHAGWWGRSCN----NQC-------------ACNSS--- 220
C C S + +C+ TG C C G+ G C+ QC AC+
Sbjct: 481 CACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRG 540
Query: 221 ----PCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYR 265
C++ SGRC CR G RCD QC RG C+ AC P ++
Sbjct: 541 TEGPGCDKASGRCLCRPGLTGPRCD---QCQRGYCNRYPVCVACHPCFQ 586
Score = 68.6 bits (166), Expect = 2e-11
Identities = 82/301 (27%), Positives = 109/301 (36%), Gaps = 73/301 (24%)
Query: 184 ACYCSA-TSRCDPQTGA-------------CLCHAGWWGRSCNNQCA--CNSSPCEQQSG 227
+C+C RC P+ GA C+C G +C +CA N+ P G
Sbjct: 249 SCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCE-RCAPFYNNRPWRPAEG 307
Query: 228 R----CQCRERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCR 283
+ CQ RCD C CH A G G C + C G C
Sbjct: 308 QDAHECQ--------RCD--CNGHSETCHFDPAVFAASQGAYGGVC-DNCRDHTEGKNCE 356
Query: 284 R-RCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNH 342
R + + ++P + C++CE CD A G C+
Sbjct: 357 RCQLHYFRNRRPGASIQETCISCE-------CDPDGAV---------------PGAPCDP 394
Query: 343 VTGKCTRCNAGWIGDRCETKCSNG----TYGEDCAFVCADC---GSGH---CDFQSGRCL 392
VTG+C C G+RC+ C G TY DC GS CD +SGRCL
Sbjct: 395 VTGQCV-CKEHVQGERCDL-CKPGFTGLTYANPQGCHRCDCNILGSRRDMPCDEESGRCL 452
Query: 393 CSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDP---VTGACHLETNQRKGVMGAGAL 449
C P V GP C+ P + A C CDP ++ C+ T Q G G L
Sbjct: 453 CLPNVVGPKCDQCAP---YHWKLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGL 509
Query: 450 L 450
+
Sbjct: 510 M 510
Score = 51.2 bits (121), Expect = 4e-06
Identities = 41/142 (28%), Positives = 60/142 (42%), Gaps = 24/142 (16%)
Query: 50 GRNVCRAPGSQVPTC--CAGWRQQ---GDECGIAVCEGNSTCSENEVCVR-PGECRCRHG 103
GR +C P P C CA + + G C C+ +++ S C + G+C CR G
Sbjct: 449 GRCLC-LPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSPQ--CNQFTGQCPCREG 505
Query: 104 YFGANCDT----KCPRQFWG---PDCKELCSCHPHGQ----CEDVTGQCTCHARRWGARC 152
+ G C +CP + +G C+ C C G C+ +G+C C G RC
Sbjct: 506 FGGLMCSAAAIRQCPDRTYGDVATGCR-ACDCDFRGTEGPGCDKASGRCLCRPGLTGPRC 564
Query: 153 EHACQCQHGTCHPRSGACRCEP 174
+ QCQ G C+ C P
Sbjct: 565 D---QCQRGYCNRYPVCVACHP 583
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.135 0.468
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,753,004
Number of Sequences: 37866
Number of extensions: 3479754
Number of successful extensions: 53317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 491
Number of HSP's successfully gapped in prelim test: 2638
Number of HSP's that attempted gapping in prelim test: 21442
Number of HSP's gapped (non-prelim): 17717
length of query: 865
length of database: 18,247,518
effective HSP length: 111
effective length of query: 754
effective length of database: 14,044,392
effective search space: 10589471568
effective search space used: 10589471568
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.