Guide to the Human Genome
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Name: NOTCH4 Sequence: fasta or formatted (2003aa) NCBI GI: 55770876
Description:

notch4 preproprotein

Referenced in:

Notch Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.9        158           3
 C cysteine           10.4        209           2
 D aspartate           4.9         98           2
 E glutamate           4.8         96           2
 F phenylalanine       2.5         50           2
 G glycine            12.3        247           3
 H histidine           3.2         64           2
 I isoleucine          1.0         20           1
 K lysine              1.6         33           2
 L leucine             9.3        187          11
 M methionine          1.0         20           1
 N asparagine          2.6         53           2
 P proline            11.0        220           3
 Q glutamine           4.9         99           2
 R arginine            4.9         98           5
 S serine              6.4        128           2
 T threonine           5.1        103           2
 V valine              3.5         70           3
 W tryptophan          1.2         25           1
 Y tyrosine            1.2         25           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   notch4 preproprotein 
NOTCH1                0.306   notch1 preproprotein 
NOTCH3                0.295   Notch homolog 3 
NOTCH2                0.286   notch 2 preproprotein 
EYS                   0.107   eyes shut homolog isoform 1 
JAG2                  0.099   jagged 2 isoform a precursor 
JAG1                  0.096   jagged 1 precursor 
JAG2                  0.093   jagged 2 isoform b precursor 
MEGF6                 0.089   EGF-like-domain, multiple 3 
SNED1                 0.081   6720455I24Rik homolog 
CRB1                  0.074   crumbs homolog 1 precursor 
FBN3                  0.074   fibrillin 3 precursor 
FBN1                  0.070   fibrillin 1 precursor 
FBN2                  0.068   fibrillin 2 precursor 
CRB2                  0.068   crumbs homolog 2 
MEGF11                0.059   multiple EGF-like-domains 11 
LTBP4                 0.055   latent transforming growth factor beta binding prot...
LTBP4                 0.055   latent transforming growth factor beta binding prot...
LTBP4                 0.055   latent transforming growth factor beta binding prot...
MEGF10                0.052   multiple EGF-like-domains 10 
DNER                  0.050   delta-notch-like EGF repeat-containing transmembran...
LTBP2                 0.050   latent transforming growth factor beta binding protei...
TNXB                  0.050   tenascin XB isoform 1 precursor 
PEAR1                 0.048   platelet endothelial aggregation receptor 1 
SVEP1                 0.048   polydom 
DLL4                  0.048   delta-like 4 protein precursor 
DLL1                  0.046   delta-like 1 
LTBP3                 0.043   latent transforming growth factor beta binding prot...
LTBP3                 0.040   latent transforming growth factor beta binding prote...
SLIT1                 0.040   slit homolog 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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