Guide to the Human Genome
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Name: NOTCH1 Sequence: fasta or formatted (2555aa) NCBI GI: 148833508
Description:

notch1 preproprotein

Referenced in:

Neurons
Notch Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.7        170           4
 C cysteine            9.6        246           1
 D aspartate           6.1        155           2
 E glutamate           5.3        136           4
 F phenylalanine       2.5         64           2
 G glycine            10.1        257           4
 H histidine           3.2         82           2
 I isoleucine          2.2         56           1
 K lysine              2.5         63           3
 L leucine             7.3        187           2
 M methionine          1.1         29           2
 N asparagine          5.9        151           3
 P proline             7.8        200           6
 Q glutamine           4.7        121           4
 R arginine            4.0        103           4
 S serine              7.4        189           4
 T threonine           5.5        141           2
 V valine              4.9        124           4
 W tryptophan          0.8         20           1
 Y tyrosine            2.4         61           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   notch1 preproprotein 
NOTCH2                0.512   notch 2 preproprotein 
NOTCH3                0.361   Notch homolog 3 
NOTCH4                0.223   notch4 preproprotein 
EYS                   0.108   eyes shut homolog isoform 1 
JAG1                  0.088   jagged 1 precursor 
FBN1                  0.087   fibrillin 1 precursor 
FBN2                  0.087   fibrillin 2 precursor 
JAG2                  0.085   jagged 2 isoform a precursor 
FBN3                  0.084   fibrillin 3 precursor 
JAG2                  0.082   jagged 2 isoform b precursor 
SNED1                 0.079   6720455I24Rik homolog 
MEGF6                 0.074   EGF-like-domain, multiple 3 
CRB1                  0.062   crumbs homolog 1 precursor 
CRB2                  0.058   crumbs homolog 2 
MEGF11                0.047   multiple EGF-like-domains 11 
TNXB                  0.046   tenascin XB isoform 1 precursor 
DLL1                  0.046   delta-like 1 
DNER                  0.044   delta-notch-like EGF repeat-containing transmembran...
SVEP1                 0.044   polydom 
LTBP2                 0.044   latent transforming growth factor beta binding protei...
MEGF10                0.044   multiple EGF-like-domains 10 
LTBP4                 0.044   latent transforming growth factor beta binding prot...
LTBP4                 0.044   latent transforming growth factor beta binding prot...
LTBP4                 0.044   latent transforming growth factor beta binding prot...
DLL4                  0.042   delta-like 4 protein precursor 
PEAR1                 0.037   platelet endothelial aggregation receptor 1 
SLIT1                 0.036   slit homolog 1 
TNC                   0.035   tenascin C precursor 
LTBP1                 0.035   latent transforming growth factor beta binding prote...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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