Guide to the Human Genome
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Search of human proteins with 118498339

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|118498339 EMI domain containing 2 [Homo sapiens]
         (439 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|118498339 EMI domain containing 2 [Homo sapiens]                   932   0.0  
gi|50511941 EMI domain containing 1 [Homo sapiens]                    297   1e-80
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     149   4e-36
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      148   8e-36
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   147   2e-35
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   147   2e-35
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      147   2e-35
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     146   3e-35
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     145   9e-35
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               145   9e-35
gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]              144   1e-34
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       144   2e-34
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   142   6e-34
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   142   6e-34
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   142   6e-34
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   142   6e-34
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   142   6e-34
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  140   2e-33
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   140   3e-33
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   140   3e-33
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   140   3e-33
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   140   3e-33
gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]      140   3e-33
gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]      140   3e-33
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   139   4e-33
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   139   7e-33
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   139   7e-33
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   139   7e-33
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          139   7e-33
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   138   9e-33

>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score =  932 bits (2410), Expect = 0.0
 Identities = 439/439 (100%), Positives = 439/439 (100%)

Query: 1   MKLALLLPWACCCLCGSALATGFLYPFSAAALQQHGYPEPGAGSPGSGYASRRHWCHHTV 60
           MKLALLLPWACCCLCGSALATGFLYPFSAAALQQHGYPEPGAGSPGSGYASRRHWCHHTV
Sbjct: 1   MKLALLLPWACCCLCGSALATGFLYPFSAAALQQHGYPEPGAGSPGSGYASRRHWCHHTV 60

Query: 61  TRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVRTLIRPTYRVSYRTVTVLEWRCCPGFT 120
           TRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVRTLIRPTYRVSYRTVTVLEWRCCPGFT
Sbjct: 61  TRTVSCQVQNGSETVVQRVYQSCRWPGPCANLVRTLIRPTYRVSYRTVTVLEWRCCPGFT 120

Query: 121 GSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNEDFLP 180
           GSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNEDFLP
Sbjct: 121 GSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNEDFLP 180

Query: 181 DAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP 240
           DAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP
Sbjct: 181 DAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP 240

Query: 241 RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
           RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG
Sbjct: 241 RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300

Query: 301 VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360
           VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE
Sbjct: 301 VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360

Query: 361 GVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQPDGVLA 420
           GVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQPDGVLA
Sbjct: 361 GVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQPDGVLA 420

Query: 421 ALLGPDPGQKSVDQASSRK 439
           ALLGPDPGQKSVDQASSRK
Sbjct: 421 ALLGPDPGQKSVDQASSRK 439


>gi|50511941 EMI domain containing 1 [Homo sapiens]
          Length = 443

 Score =  297 bits (760), Expect = 1e-80
 Identities = 192/464 (41%), Positives = 234/464 (50%), Gaps = 104/464 (22%)

Query: 9   WACCCLCGSALATGFLYPFSAAALQQHGYPEPGAGSPGSGYASRRHWCHHTVTRTVSCQV 68
           WA  CL       G L P   AA      P          ++ RR+WC + VTRT+SC V
Sbjct: 7   WALLCL-------GLLLPGGGAAWSIGAAP----------FSGRRNWCSYVVTRTISCHV 49

Query: 69  QNGSETVVQRVYQSCRWPGPC-ANLVRTLIRPTYRVSYRTVTVLEWRCCPGFTGSNCDEE 127
           QNG  T +QRV Q+C WP  C  +  RT++RPTY+V Y+ VT  EWRCCPG +G +C+E 
Sbjct: 50  QNG--TYLQRVLQNCPWPMSCPGSSYRTVVRPTYKVMYKIVTAREWRCCPGHSGVSCEEV 107

Query: 128 ----------------------------CMNCTRLSDMSERLTTLEAKVLLLEAAERPSS 159
                                       C+NC+++S+++ERL  LEAK+ +L   E+P  
Sbjct: 108 AASSASLEPMWSGSTMRRMALRPTAFSGCLNCSKVSELTERLKVLEAKMTMLTVIEQPVP 167

Query: 160 PDNDLPA-PESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKG 218
           P    PA PE   P W         P A   P         G  G  GP GP G  GS+G
Sbjct: 168 PT---PATPEDPAPLWGP-------PPAQGSPGDGGLQDQVGAWGLPGPTGPKGDAGSRG 217

Query: 219 DRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQP 278
             G  G  GP GPPG  G  G  G PGE G PGPPGPPGP G   P+P  P  A  S   
Sbjct: 218 PMGMRGPPGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPG--PPAPVGPPHARIS--- 272

Query: 279 PTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGS---------- 328
                +GD  L++   +T      GP GPPGPPGP GP GPPGP G PGS          
Sbjct: 273 ----QHGDPLLSNTFTETNNHWPQGPTGPPGPPGPMGPPGPPGPTGVPGSPGHIGPPGPT 328

Query: 329 --------------QGLAGE---RGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREALKI 371
                         +GL GE   +G+ G  GEPG KG+ GEK+    GEG+ QLREALKI
Sbjct: 329 GPKGISGHPGEKGERGLRGEPGPQGSAGQRGEPGPKGDPGEKSHW--GEGLHQLREALKI 386

Query: 372 LAERVLILEHMIGIHDP-LASPEG--GSGQDAALRANLKMKRGG 412
           LAERVLILE MIG+++P L S  G  G+G  + LR     KRGG
Sbjct: 387 LAERVLILETMIGLYEPELGSGAGPAGTGTPSLLRG----KRGG 426


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  149 bits (377), Expect = 4e-36
 Identities = 96/240 (40%), Positives = 107/240 (44%), Gaps = 52/240 (21%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHP--VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQ 222
            P P   P    E   P    +A P   P +R  TGP GP G  G PG  G PG KG+RG 
Sbjct: 770  PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA 829

Query: 223  TGEKGPAGPPGLLGPPG------------------------------PRGLPGEMGRPGP 252
             GEKG  GPPG+ GPPG                               RGLPG  G  G 
Sbjct: 830  PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889

Query: 253  PGPPGPAGNPG----PSPNSPQGALYSL----------QPPTDKDNGDSRLASAIVDTVL 298
            PGPPGP+G+PG    P P    GA  S           QP      G      A     +
Sbjct: 890  PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949

Query: 299  AGVPGPRGPPGPPGPPGPRGPPGPPGT------PGSQGLAGERGTVGPSGEPGVKGEEGE 352
            AG+ G RG  GPPG PGPRG PGP G       PG+ GL+GERG  GP G PG+ G  GE
Sbjct: 950  AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009



 Score =  146 bits (368), Expect = 4e-35
 Identities = 81/166 (48%), Positives = 86/166 (51%), Gaps = 24/166 (14%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GPPG+ G  GP GPPG  G  G  G+ GP GP GL G PG  G PGE G+PG PGP 
Sbjct: 603 GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662

Query: 257 GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGP-- 313
           G AG PG P      GA     PP                  LAG PG RG  GPPGP  
Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPG-----------------LAGAPGLRGGAGPPGPEG 705

Query: 314 ----PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
                GP GPPG  GTPG QG+ GERG +G  G  G KGE G   A
Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751



 Score =  138 bits (348), Expect = 9e-33
 Identities = 85/192 (44%), Positives = 90/192 (46%), Gaps = 45/192 (23%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG----PAGP-----------PGL 234
           P  R P GP G PG+ GP G  G PG  G RG  GE G    P GP           PG 
Sbjct: 488 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 235 LGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLA 290
            G PGP G  GE GRPGPPGP GP G PG    P P    GA     P  + + G     
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGA-----PGKNGERGGP--- 599

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP---------PGTPGSQGLAGERGTVGPS 341
                    G PGP+GPPG  G  GP+GPPGP          G PG QGL G  GT GP 
Sbjct: 600 ---------GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 342 GEPGVKGEEGEK 353
           GE G  GE G K
Sbjct: 651 GENGKPGEPGPK 662



 Score =  137 bits (345), Expect = 2e-32
 Identities = 104/261 (39%), Positives = 117/261 (44%), Gaps = 33/261 (12%)

Query: 193  RRPTGPAGPPGQTGPPGP------------AGPPGSKGDRGQTGEKGPAGPPGLLGP--- 237
            R PTGP GPPG  G PG             AGP GS G+RG+TG  GPAG PG  G    
Sbjct: 761  RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE 820

Query: 238  ---PGPRGLPGEMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPTDKDNGDSRLASAI 293
                G RG PGE G  GPPG  GP G  GP+ P  PQG       P     G    A   
Sbjct: 821  PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP-----GGPGAAGFP 875

Query: 294  VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
                L G PG  G PGPPGP G  G  GPPG  G+ G  G  G  GP G+ G  GE+G  
Sbjct: 876  GARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSP 935

Query: 354  AATAEGEGVQQLREALKILAERVLILEHMIGIHDPLAS--PEGGSGQDAALRAN-LKMKR 410
             A         L  A  I   R   L    G+  P  S  P+G  G+     AN L  +R
Sbjct: 936  GAQGPPGAPGPLGIA-GITGARG--LAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGER 992

Query: 411  GGAQPDGV--LAALLGPDPGQ 429
            G   P G+  LA   G +PG+
Sbjct: 993  GPPGPQGLPGLAGTAG-EPGR 1012



 Score =  137 bits (344), Expect = 3e-32
 Identities = 83/197 (42%), Positives = 90/197 (45%), Gaps = 36/197 (18%)

Query: 184 PLAHPVPRQRRPTGPAGPPGQTGP---------------PGPAGPPGSKGDRGQTGEKGP 228
           P A  VP +  P GP GP G  GP               PG AGP GS G+RG+TG  GP
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 229 AGPPGLLGP------PGPRGLPGEMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPTD 281
           AG PG  G        G RG PGE G  GPPG  GP G  GP+ P  PQG       P  
Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG 868

Query: 282 KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
                            AG PG RG PGPPG  G  GPPGP G+PG  G  G  G  G  
Sbjct: 869 PG--------------AAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAP 914

Query: 342 GEPGVKGEEGEKAATAE 358
           G PGV G +G+     E
Sbjct: 915 GSPGVSGPKGDAGQPGE 931



 Score =  135 bits (339), Expect = 1e-31
 Identities = 83/199 (41%), Positives = 91/199 (45%), Gaps = 33/199 (16%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP------GPRG 242
           +P    P G  G PG+ GP G AG PG+ G +G  G  G  GPPGL G P      GP G
Sbjct: 643 LPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG 702

Query: 243 LPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             G  G  GPPGPPG AG PG       +G L S  P  DK       A  +      G 
Sbjct: 703 PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV-----PGK 757

Query: 302 PGPRGPPGPPGPPGPRGPPGP---------PGTPGSQGLAGERGTVGP------------ 340
            GPRGP GP GPPGP G PG          PG  G +G  GERG  GP            
Sbjct: 758 DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQ 817

Query: 341 SGEPGVKGEEGEKAATAEG 359
           +GEPG KGE G      EG
Sbjct: 818 NGEPGGKGERGAPGEKGEG 836



 Score =  134 bits (336), Expect = 2e-31
 Identities = 76/169 (44%), Positives = 86/169 (50%), Gaps = 12/169 (7%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G  G PG  G PG  G PG KGDRG+ G  G  G PG  GPPGP G  G+ G  G  GP 
Sbjct: 1011 GRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPA 1070

Query: 257  GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIV-DTVLAGVPGPRGPPGP----- 310
            GPAG PGP+    +GA     P  DK     R A+ I       G PG  G PGP     
Sbjct: 1071 GPAGAPGPA--GSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128

Query: 311  ----PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
                PGP GPRGP GP G PG  G +G  G +GP G  G +GE G + +
Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGS 1177



 Score =  131 bits (329), Expect = 1e-30
 Identities = 80/195 (41%), Positives = 94/195 (48%), Gaps = 38/195 (19%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKG---------DRGQTGEKGPAGPPGLLGPPGPRGLPGEM 247
           GPAGPPG  GPPG +G PGS G         + GQ G  GP GPPG +GP GP G  GE 
Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGES 233

Query: 248 GRPGPPGP---PGPAGNPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG-- 300
           GRPG PG    PGP G  GP+  P  P    +      + + G++       +  L G  
Sbjct: 234 GRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293

Query: 301 -VPGPRGP---------PGPPGPPGPR------------GPPGPPGTPGSQGLAGERGTV 338
             PGP GP         PG PG  G R            GPPGPPGT G  G  G +G V
Sbjct: 294 GAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEV 353

Query: 339 GPSGEPGVKGEEGEK 353
           GP+G PG  G  G++
Sbjct: 354 GPAGSPGSNGAPGQR 368



 Score =  128 bits (321), Expect = 1e-29
 Identities = 76/174 (43%), Positives = 83/174 (47%), Gaps = 37/174 (21%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLG------PPGPRGLPGEMGRP 250
            G  G PG  GPPGP GP G  GDRG++G  GPAG PG  G      P GPRG  GE G  
Sbjct: 1041 GAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGER 1100

Query: 251  GP---------PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
            G          PG PG  G+PGP+    QGA+ S  P                    AG 
Sbjct: 1101 GAAGIKGHRGFPGNPGAPGSPGPA--GQQGAIGSPGP--------------------AGP 1138

Query: 302  PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
             GP GP GPPG  G  G PGP G PG +G  GERG+ G  G PG  G  G   A
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192



 Score =  127 bits (320), Expect = 2e-29
 Identities = 74/166 (44%), Positives = 83/166 (50%), Gaps = 25/166 (15%)

Query: 198 PAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPG 257
           P  P   T PP   GP G KGD          GPPG+ G  G  G+PG+ G PG PGPPG
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGD---------PGPPGIPGRNGDPGIPGQPGSPGSPGPPG 139

Query: 258 PAGN--PGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG 315
              +   GP   SPQ   Y ++             S +    LAG PGP GPPGPPGPPG
Sbjct: 140 ICESCPTGPQNYSPQYDSYDVK-------------SGVAVGGLAGYPGPAGPPGPPGPPG 186

Query: 316 PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKA-ATAEGE 360
             G PG PG+PG QG  GE G  GPSG PG  G  G    A  +GE
Sbjct: 187 TSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232



 Score =  125 bits (313), Expect = 1e-28
 Identities = 76/192 (39%), Positives = 85/192 (44%), Gaps = 45/192 (23%)

Query: 197 GPAGPPGQTGPPG---------PAGPPGSKGDRGQTG---------EKGPAGPPGLLGPP 238
           GP GPPG  G PG           G PG KGD+G+ G         + GP GP G +GPP
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770

Query: 239 GPRGLPGEMGRPGPP------------------GPPGPAGNPG-PSPNSPQGALYSLQPP 279
           GP G PG+ G  G P                  GPPGPAG PG P  N   G       P
Sbjct: 771 GPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAP 830

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
            +K  G            +AG PG  GP GPPGP G +G  G PG PG+ G  G RG  G
Sbjct: 831 GEKGEGG--------PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG 882

Query: 340 PSGEPGVKGEEG 351
           P G  G  G  G
Sbjct: 883 PPGSNGNPGPPG 894



 Score =  123 bits (309), Expect = 3e-28
 Identities = 74/181 (40%), Positives = 85/181 (46%), Gaps = 19/181 (10%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL---G 236
           P   P ++  P QR   GP G  G  GPPGP G  GS G +G+ G  G  G PGL+   G
Sbjct: 355 PAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414

Query: 237 PPGP---RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAI 293
           PPGP    G PG  G  G PG  G  G PGP     +  +  +     +D  D       
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGS----- 469

Query: 294 VDTVLAGVPGPRGPPGPP---GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                 G PG  G PG     G PG RGP GP G PG +G AGERG  GP+G  G  GE 
Sbjct: 470 -----PGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP 524

Query: 351 G 351
           G
Sbjct: 525 G 525



 Score =  121 bits (304), Expect = 1e-27
 Identities = 72/165 (43%), Positives = 82/165 (49%), Gaps = 18/165 (10%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGD---RGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P GP G PG+ G PG  G  G++G+   RG  G+ GP GPPG  G PG  G  GE+G  G
Sbjct: 298 PMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG 357

Query: 252 PPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            PG  G  G  G P P    GA     PP    +   +           G  GP G PG 
Sbjct: 358 SPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGK-----------GEMGPAGIPGA 406

Query: 311 PGPPGPRGPPGPP---GTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           PG  G RGPPGP    G PG +G AGE G  G  GEPG +GE GE
Sbjct: 407 PGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGE 451



 Score =  121 bits (303), Expect = 1e-27
 Identities = 74/171 (43%), Positives = 84/171 (49%), Gaps = 19/171 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR---PGPP 253
           G  G  GQ GPPGP G  G  G  G  GE GPAG PG  G PG RG PG  G     GPP
Sbjct: 324 GARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPP 383

Query: 254 GPPGPAGNPGPS--------PNSPQGALYSLQPPTDKD-NGDSRLASAIVDTVLAGVPGP 304
           GPPG  G+PG          P +P G + +  PP     NG   L         AG PG 
Sbjct: 384 GPPGINGSPGGKGEMGPAGIPGAP-GLMGARGPPGPAGANGAPGLRGG------AGEPGK 436

Query: 305 RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G  G PGP G RG  G PG PG++G  G+ G+ G  G  G+ G  GE+ A
Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487



 Score =  121 bits (303), Expect = 1e-27
 Identities = 79/183 (43%), Positives = 88/183 (48%), Gaps = 32/183 (17%)

Query: 195  PTGPAGPPGQTGPPGPAG---PPGS------KGDRGQTGEKGPAG---PPGLLGPPGPRG 242
            P GP+G PG+ GPPGPAG    PGS      KGD GQ GEKG  G   PPG  GP G  G
Sbjct: 892  PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951

Query: 243  LPGEMGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTV 297
            + G  G  GPPG PGP G+PGP         P     S +       G   LA       
Sbjct: 952  ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT----- 1006

Query: 298  LAGVPGPRGPP---------GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
             AG PG  G P         G PG  G RG  G PG PG+ G  G  G VGP+G+ G +G
Sbjct: 1007 -AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 349  EEG 351
            E G
Sbjct: 1066 ESG 1068



 Score =  119 bits (299), Expect = 4e-27
 Identities = 75/182 (41%), Positives = 85/182 (46%), Gaps = 26/182 (14%)

Query: 197 GPAGPPGQTGPPG---------PAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEM 247
           GP GPPG  G PG         PAG PGS G  GQ GE GP G  G  GPPGP   PG  
Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP---PGIN 389

Query: 248 GRPGPPGPPGPAGNPG----------PSPNSPQGAL----YSLQPPTDKDNGDSRLASAI 293
           G PG  G  GPAG PG          P P    GA      + +P  +   G+       
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            +  + GVPG +G  G  G PG  G  G PG  G +G  G RG  GP+G PG KG  GE+
Sbjct: 450 GEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER 509

Query: 354 AA 355
            A
Sbjct: 510 GA 511



 Score =  117 bits (293), Expect = 2e-26
 Identities = 81/211 (38%), Positives = 91/211 (43%), Gaps = 38/211 (18%)

Query: 165 PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAG-----PPGSKGD 219
           P   + PP       P   P    +P +    G  G PG  G PGP G     P G +  
Sbjct: 92  PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNY 151

Query: 220 R---------------GQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGP 264
                           G  G  GPAGPPG  GPPG  G PG  G PG  GPPG  G  GP
Sbjct: 152 SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP 211

Query: 265 S-PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGP---P 320
           S P  P GA+     P  KD G+S            G PG  G  G PGPPG +GP   P
Sbjct: 212 SGPPGPPGAI-GPSGPAGKD-GES------------GRPGRPGERGLPGPPGIKGPAGIP 257

Query: 321 GPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           G PG  G +G  G  G  G +G PG+KGE G
Sbjct: 258 GFPGMKGHRGFDGRNGEKGETGAPGLKGENG 288



 Score =  115 bits (289), Expect = 6e-26
 Identities = 80/206 (38%), Positives = 89/206 (43%), Gaps = 36/206 (17%)

Query: 156 RPSSP-DNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGP------- 207
           RP  P +  LP P            P  IP    +   R   G  G  G+TG        
Sbjct: 235 RPGRPGERGLPGPPGIKG-------PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 208 --PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS 265
             PG  G PG  G RG  GE+G  G PG  G  G  G  G  G+PGPPGPPG AG PG S
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPG-S 346

Query: 266 PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGT 325
           P    GA   + P     +               G PG RG PGP G  G +GPPGPPG 
Sbjct: 347 P----GAKGEVGPAGSPGSN--------------GAPGQRGEPGPQGHAGAQGPPGPPGI 388

Query: 326 PGSQGLAGERGTVGPSGEPGVKGEEG 351
            GS G  GE G  G  G PG+ G  G
Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARG 414



 Score =  112 bits (281), Expect = 5e-25
 Identities = 81/210 (38%), Positives = 93/210 (44%), Gaps = 39/210 (18%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLG 236
           P  IP A  +   R P GPAG  G  G  G AG PG   +KG+ G  GE+G AG PG+ G
Sbjct: 400 PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPG 459

Query: 237 P------------PGPRGLPG---EMGRPGPPGPPGPAGNPG----------PSPNSPQG 271
                        PG  GLPG   E G PG  GP GP G PG          P P  P+G
Sbjct: 460 AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG 519

Query: 272 ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL 331
           A  + +P  D   G   +          G+PG  G PG  G PGP G  G  G PG  G 
Sbjct: 520 A--AGEPGRDGVPGGPGMR---------GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 332 AGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
           +G RG  G  G PG KG +G      E  G
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGG 598



 Score =  102 bits (253), Expect = 9e-22
 Identities = 77/247 (31%), Positives = 94/247 (38%), Gaps = 83/247 (33%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG--------------------------- 227
            P GPAG PG  G  G  GP G +GD+G+TGE+G                           
Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128

Query: 228  ------PAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTD 281
                  PAGP G +GP GP G  G  G PGP GPPGP GN                    
Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGN-------------------- 1168

Query: 282  KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
                                 G RG  G PG PG  GPPGPPG PG        G VG +
Sbjct: 1169 --------------------RGERGSEGSPGHPGQPGPPGPPGAPGPC-----CGGVGAA 1203

Query: 342  GEPGVKGEEGEKAATAEGEGVQQLREALKILAERVLI-LEHMIGIHDPLASPEGGSGQDA 400
               G+ GE+    A   G+         KI  + ++  L+ + G  + L SP+G     A
Sbjct: 1204 AIAGIGGEKAGGFAPYYGDEPMD----FKINTDEIMTSLKSVNGQIESLISPDGSRKNPA 1259

Query: 401  ALRANLK 407
                +LK
Sbjct: 1260 RNCRDLK 1266



 Score = 38.5 bits (88), Expect = 0.012
 Identities = 23/69 (33%), Positives = 27/69 (39%)

Query: 283 DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSG 342
           D+G       I D      P P  P G      P+ P  P   P  QG  G +G  GP G
Sbjct: 56  DSGSVLCDDIICDDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPG 115

Query: 343 EPGVKGEEG 351
            PG  G+ G
Sbjct: 116 IPGRNGDPG 124


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  148 bits (374), Expect = 8e-36
 Identities = 91/228 (39%), Positives = 107/228 (46%), Gaps = 35/228 (15%)

Query: 157  PSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS 216
            P  P    PA +  PP    D   D  P     P      GP+GPPG+ GPPGPAGP G 
Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGD---DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGR 1403

Query: 217  KGDRGQTGEKGPAGPPGLLGPPGP------------RGLPGEMGRPGPPGPPGPAGNPGP 264
            +G++G  GE G  GPPG  GP GP            RG+PG +G  G PG PGP G PGP
Sbjct: 1404 QGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGP 1463

Query: 265  --SPNSP--------------QGALYSLQPPTDK-DNGDSRL---ASAIVDTVLAGVPGP 304
               P  P               G +  + PP ++ + GD  L     +       G+ GP
Sbjct: 1464 MGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGP 1523

Query: 305  RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
             GP GPPGPPG  GPPGP G  GS G  G +G  G  G PG  G  GE
Sbjct: 1524 SGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score =  147 bits (372), Expect = 1e-35
 Identities = 82/181 (45%), Positives = 93/181 (51%), Gaps = 33/181 (18%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP---- 252
           GPAGP G TG PGP GPPGS G +G+ G+ GP GP G+ GPPGP G PG  GR G     
Sbjct: 559 GPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGAR 618

Query: 253 --PGPPGPAGNPG----------------PSPNSPQGALYSLQPPTDKDNGDSRLASAIV 294
             PG  GP G+ G                P P+ P G      P  D + GD      + 
Sbjct: 619 GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG-----PPGDDGERGDD---GEVG 670

Query: 295 DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKA 354
              L G PGPRG  GP GPP   GPPGPPG  G  G  G +G VGP GEPG  G++G   
Sbjct: 671 PRGLPGEPGPRGLLGPKGPP---GPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPG 727

Query: 355 A 355
           A
Sbjct: 728 A 728



 Score =  140 bits (354), Expect = 2e-33
 Identities = 84/188 (44%), Positives = 95/188 (50%), Gaps = 27/188 (14%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKG------DRGQTG---EKGPAGPPGLLGPPGP 240
            P +R P GP GP G  GP GP GPPG  G       RG+TG   + GP GPPG++GP GP
Sbjct: 945  PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGP 1004

Query: 241  RGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G  G MG  G PGPPGP G  G P     +G        T  D G + L        L 
Sbjct: 1005 TGETGPMGERGHPGPPGPPGEQGLPGLAGKEG--------TKGDPGPAGLPGKDGPPGLR 1056

Query: 300  GVPGPRGPPGP------PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVK---GEE 350
            G PG RG PGP       G  GP GPPGP G+PG +G AG  G +G  G PG +   G  
Sbjct: 1057 GFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPA 1116

Query: 351  GEKAATAE 358
            GEK A  E
Sbjct: 1117 GEKGAPGE 1124



 Score =  140 bits (354), Expect = 2e-33
 Identities = 80/194 (41%), Positives = 95/194 (48%), Gaps = 32/194 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP---RGLPG------ 245
            PTGP GP GQ GP G  G PG +G +G  G+KG  GP G  GPPGP   +GLPG      
Sbjct: 1181 PTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKG 1240

Query: 246  ------EMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPTDKDN-------------- 284
                  +MG PGPPGP GP+G PG   P  P G + +     +K                
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGG 1300

Query: 285  --GDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSG 342
              G         ++  +G  GP GP GPPG  GP+G PGP G PG  G  GE G  G  G
Sbjct: 1301 PPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDG 1360

Query: 343  EPGVKGEEGEKAAT 356
             PG KG++GE   T
Sbjct: 1361 PPGDKGDDGEPGQT 1374



 Score =  140 bits (353), Expect = 2e-33
 Identities = 79/166 (47%), Positives = 89/166 (53%), Gaps = 27/166 (16%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP---AGPPGLLGPP---GPRGLPGEMGRP 250
            G  G  G+ G PG  GPPG KG+RG+ GE GP   AGPPG  GPP   GP+G PG +G P
Sbjct: 1285 GEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFP 1344

Query: 251  GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPG 309
            G PGPP   G PGP+            PP DK D+G+             G PGP G PG
Sbjct: 1345 GDPGPP---GEPGPAGQD--------GPPGDKGDDGEPG---------QTGSPGPTGEPG 1384

Query: 310  PPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            P GPPG RGPPGP G  G QG  G +G  G  G PG  G  G + A
Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGA 1430



 Score =  140 bits (353), Expect = 2e-33
 Identities = 80/179 (44%), Positives = 88/179 (49%), Gaps = 20/179 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP GPPG  GP G  GP G  GD G  GE GPAG  G  G  G  G PG+ G PGP G
Sbjct: 1322 PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTG 1381

Query: 255  PPGPAGNPG----PSPNSPQGAL--------YSLQPPTDKDN--GDSRLASAIVDTVLAG 300
             PGP+G PG    P P  P+G            L+ P  K    G            L G
Sbjct: 1382 EPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRG 1441

Query: 301  VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV------KGEEGEK 353
            +PGP G  G PG PGP GPPGP G PG  GL G+ G  G  G PG+       GE+GEK
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500



 Score =  138 bits (348), Expect = 9e-33
 Identities = 87/216 (40%), Positives = 91/216 (42%), Gaps = 51/216 (23%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP----- 244
            P +R P G AGP G  G PGP GPPG  G++G  GEKGP GP G  G  GP GLP     
Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 245  -------------------------GEMGRPGPPGPPGPAGNPGPS-------PNSPQGA 272
                                     GE G PGP GP GP G PGPS       P   QG 
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208

Query: 273  LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP---------GPPGPPGPRGPPGPP 323
                      D G            L G+PGP G           GPPGPPGPRGP G P
Sbjct: 1209 F-----GQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAP 1263

Query: 324  GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
            G  G QG  G  G  G  GE G  GE GE     EG
Sbjct: 1264 GADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299



 Score =  137 bits (344), Expect = 3e-32
 Identities = 77/167 (46%), Positives = 82/167 (49%), Gaps = 15/167 (8%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P G  G  G  GPPGP GP GS G+RG  G  GP G PG  GP GP G  GE G PG  G
Sbjct: 1067 PVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKG 1126

Query: 255  PPGPAGNPG-------PSPNSPQGALYSLQPPTDKDN---GDSRLASAIVDTVLAGVPGP 304
            P GPAG  G       P P  P G      P  D D    G+     +  D    G PGP
Sbjct: 1127 PQGPAGRDGLQGPVGLPGPAGPVG-----PPGEDGDKGEIGEPGQKGSKGDKGEQGPPGP 1181

Query: 305  RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
             GP GP G PGP G  G PG  G QGL G++G  GP G PG  G  G
Sbjct: 1182 TGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVG 1228



 Score =  136 bits (343), Expect = 3e-32
 Identities = 80/177 (45%), Positives = 89/177 (50%), Gaps = 23/177 (12%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  G  G  G PGP+GPPG  GD G+ G+ G  GP GL G PGPRGL G  G PGPPGPP
Sbjct: 637 GLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPP 696

Query: 257 GPAG---NPGPSPN-SPQGALYSLQPPTDKDN-------------GDSRLASAIVDTVLA 299
           G  G    PGP  N  PQG      PP  + N             G       +    L 
Sbjct: 697 GVTGMDGQPGPKGNVGPQG---EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLP 753

Query: 300 GVPGPRGPPGPP---GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G+PG  GPPG P   GPPG +G  GPPG  G  G  G RG  G  G  G+KG +GEK
Sbjct: 754 GMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEK 810



 Score =  135 bits (339), Expect = 1e-31
 Identities = 89/222 (40%), Positives = 101/222 (45%), Gaps = 37/222 (16%)

Query: 157  PSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS 216
            P  P    P P+  P    +D LP      HP  R     G  G  G+TGPPGP G  G 
Sbjct: 953  PQGPTG-FPGPKGPPGPPGKDGLP-----GHPGQR-----GETGFQGKTGPPGPPGVVGP 1001

Query: 217  KGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG------------- 263
            +G  G+TG  G  G PG  GPPG +GLPG  G+ G  G PGPAG PG             
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061

Query: 264  ---PSPNSPQGALYSLQPPTDK----DNGDSRLASAIVDTVLAGVPGPRGPPGP------ 310
               P P    G   +  PP         G+   A A     + G PGP+GPPGP      
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121

Query: 311  PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            PG  GP+GP G  G  G  GL G  G VGP GE G KGE GE
Sbjct: 1122 PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE 1163



 Score =  134 bits (338), Expect = 1e-31
 Identities = 79/173 (45%), Positives = 89/173 (51%), Gaps = 20/173 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            P GP GPPG+ G  G  G PG   SKGD+G+ G  GP GP G +G PGP G  GE G  G
Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204

Query: 252  PPGPPGPAGNPG----PSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG 306
              G  G  G+ G    P P  P G      PP +K + GD      +      G PGPRG
Sbjct: 1205 QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD------VGQMGPPGPPGPRG 1258

Query: 307  PPGPPGPPGPRGPPGPPGTPGS------QGLAGERGTVGPSGEPGVKGEEGEK 353
            P G PG  GP+GPPG  G PG+       G AGE G  G  G PG KGE GEK
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311



 Score =  132 bits (333), Expect = 5e-31
 Identities = 75/171 (43%), Positives = 86/171 (50%), Gaps = 18/171 (10%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P +  P G  G PG  G PGP G  G KG+ G  G  GPAG PG  GP G  G  G  G
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 249  RPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGP 307
            RPGP GPPGPAG  G P    PQG       P  +D     +          G+PGP GP
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQG-------PAGRDGLQGPV----------GLPGPAGP 1148

Query: 308  PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
             GPPG  G +G  G PG  GS+G  GE+G  GP+G  G  G+ G   A  E
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGE 1199



 Score =  131 bits (329), Expect = 1e-30
 Identities = 74/176 (42%), Positives = 84/176 (47%), Gaps = 30/176 (17%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR 249
           P  R   GP GPPG  GPPG  G  G  G +G  G +G  GPPG  G PG +GLPG  G 
Sbjct: 678 PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 250 PGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            GPPG  GP G PG    P  + P G      P  +                  G PG +
Sbjct: 738 IGPPGEKGPLGKPGLPGMPGADGPPG-----HPGKE------------------GPPGEK 774

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGE---PGVKGEEGEKAATAE 358
           G  GPPGP GP G PGP G  G+ G+ G +GT G  GE   PG KG+ G K    E
Sbjct: 775 GGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGE 830



 Score =  130 bits (328), Expect = 2e-30
 Identities = 76/166 (45%), Positives = 84/166 (50%), Gaps = 23/166 (13%)

Query: 188  PVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEM 247
            P PR +R  GP GP G+ GP G  G PG KG+   +G  GPAGPPG  GP GP+G  G  
Sbjct: 906  PGPRGQR--GPTGPRGERGPRGITGKPGPKGN---SGGDGPAGPPGERGPNGPQGPTGFP 960

Query: 248  GRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
            G  GPPGPPG  G PG P      G      PP                    GV GP+G
Sbjct: 961  GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP-----------------PGVVGPQG 1003

Query: 307  PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            P G  GP G RG PGPPG PG QGL G  G  G  G+PG  G  G+
Sbjct: 1004 PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGK 1049



 Score =  129 bits (325), Expect = 4e-30
 Identities = 85/194 (43%), Positives = 94/194 (48%), Gaps = 40/194 (20%)

Query: 184 PLAHPVPRQRRPT-GPAGPPGQTGPPGP------AGPPGSKGDRGQTGEKGPAGPPGLLG 236
           P   P  R R  + G  G PGQTGP G       AG PG KG RG  G  GP GPPG  G
Sbjct: 602 PAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDG 661

Query: 237 PPG------PRGLPGE------MGRPGPPGPPGPA------GNPGPSPN-SPQGALYSLQ 277
             G      PRGLPGE      +G  GPPGPPGP       G PGP  N  PQG      
Sbjct: 662 ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG---EPG 718

Query: 278 PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT 337
           PP  + N  ++           G+PGP+G  GPPG  GP G PG PG PG+ G  G  G 
Sbjct: 719 PPGQQGNPGAQ-----------GLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK 767

Query: 338 VGPSGEPGVKGEEG 351
            GP GE G +G  G
Sbjct: 768 EGPPGEKGGQGPPG 781



 Score =  129 bits (325), Expect = 4e-30
 Identities = 77/173 (44%), Positives = 86/173 (49%), Gaps = 29/173 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---GPRGLPGEMGRPG 251
            P G  G  G  G  GP GPPG +G  G  G  GP GPPG +G P   G +G PGE G PG
Sbjct: 1235 PPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294

Query: 252  PP---GPPGPAGNPGPSPNS-PQGALYSLQPPTDK----DNGDSRLASAIVDTVLAGVPG 303
             P   GPPGP G  G    S P GA     PP  K    D+G              G PG
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGA---AGPPGPKGPPGDDGPK------------GSPG 1339

Query: 304  P---RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            P    G PGPPG PGP G  GPPG  G  G  G+ G+ GP+GEPG  G  G++
Sbjct: 1340 PVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKR 1392



 Score =  123 bits (308), Expect = 4e-28
 Identities = 71/169 (42%), Positives = 77/169 (45%), Gaps = 19/169 (11%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP G PG  GPPG  G  G  G  G  G +GP G  G  G PG  G  G  G PG PGP 
Sbjct: 850  GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPR 909

Query: 257  GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGP--- 313
            G  G  GP        +     P     GD            AG PG RGP GP GP   
Sbjct: 910  GQRGPTGPRGERGPRGITGKPGPKGNSGGDGP----------AGPPGERGPNGPQGPTGF 959

Query: 314  PGPRGPPGPPGT------PGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
            PGP+GPPGPPG       PG +G  G +G  GP G PGV G +G    T
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET 1008



 Score =  113 bits (282), Expect = 4e-25
 Identities = 72/186 (38%), Positives = 83/186 (44%), Gaps = 16/186 (8%)

Query: 184 PLAHP----VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
           P  HP     P ++   GP GP G  G PGP G  G+ G RG  G KG  G  G  G  G
Sbjct: 761 PPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKG 820

Query: 240 PRGLPGEMGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
             G+ G+ G  GPPGP G  G  GP     P G    L PP +K          +    L
Sbjct: 821 DMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK--------GKLGVPGL 872

Query: 299 AGVPGPRGPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G PG +GP G    PG PG  G  G  GTPG  G  G+RG  GP GE G +G  G+   
Sbjct: 873 PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932

Query: 356 TAEGEG 361
                G
Sbjct: 933 KGNSGG 938



 Score =  111 bits (277), Expect = 1e-24
 Identities = 72/190 (37%), Positives = 80/190 (42%), Gaps = 40/190 (21%)

Query: 197 GPAGPPGQTG-------------PPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
           GP G  GQ G             PPGP GP G  G  G  G  G  G PG  GPPG  GL
Sbjct: 447 GPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGL 506

Query: 244 PGEMGRPGPPGP----------PGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAI 293
           PG  G PGPPG            G AG+ GP  ++ +      Q           L    
Sbjct: 507 PGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES-----QAQAILQQARLALRGPA 561

Query: 294 VDTVLAGVPGPRGPP------------GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
               L G PGP GPP            GP GP G +GPPGP G PG +G AG  G  G  
Sbjct: 562 GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMP 621

Query: 342 GEPGVKGEEG 351
           G+ G KG+ G
Sbjct: 622 GQTGPKGDRG 631



 Score =  105 bits (263), Expect = 6e-23
 Identities = 65/167 (38%), Positives = 79/167 (47%), Gaps = 22/167 (13%)

Query: 195 PTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P G  GPPG+ GP   PG  G PG+ G  G  G++GP G  G  GPPGP+   G +G PG
Sbjct: 734 PQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQ---GPIGYPG 790

Query: 252 PPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP- 310
           P G  G  G  G                T  + G+        D  + G  G  GPPGP 
Sbjct: 791 PRGVKGADGIRG-------------LKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPR 837

Query: 311 --PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
              GP GP+G  GP G PG  G  GE+G +G  G PG  G +G K +
Sbjct: 838 GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884



 Score =  105 bits (263), Expect = 6e-23
 Identities = 68/176 (38%), Positives = 79/176 (44%), Gaps = 34/176 (19%)

Query: 190 PRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTG---EKGPAGPPGLLGPPGPRGL 243
           P  R   GP GP G+ GP   PGP GPPG KG  G  G     G  GP G +G PG  G 
Sbjct: 834 PGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGA 893

Query: 244 PGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
            GE G  G PG PGP G  GP+   P+G           + G              G+ G
Sbjct: 894 NGEKGGRGTPGKPGPRGQRGPT--GPRG-----------ERGPR------------GITG 928

Query: 304 PRGPPGPPGPPGPRGPP---GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
             GP G  G  GP GPP   GP G  G  G  G +G  GP G+ G+ G  G++  T
Sbjct: 929 KPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984



 Score = 80.9 bits (198), Expect = 2e-15
 Identities = 64/198 (32%), Positives = 70/198 (35%), Gaps = 76/198 (38%)

Query: 198 PAGPPGQTGPPGPAGPPGS-KGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           P   P + GP  PA      +G  G  GEKG  G P ++ P         M   GPPGP 
Sbjct: 423 PTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPG--------MLIEGPPGPE 474

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           GPAG PGP             P T    G              G PG RGPPG PG PG 
Sbjct: 475 GPAGLPGP-------------PGTMGPTGQ------------VGDPGERGPPGRPGLPGA 509

Query: 317 RGPPGPPGT------------------------------------------PGSQGLAGE 334
            G PGPPGT                                           G  GL G 
Sbjct: 510 DGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGR 569

Query: 335 RGTVGPSGEPGVKGEEGE 352
            G VGP G  G+KGE G+
Sbjct: 570 PGPVGPPGSGGLKGEPGD 587



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 52/146 (35%), Positives = 61/146 (41%), Gaps = 23/146 (15%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRP--TGPAGPPGQTGP------PGPAGPPGS 216
            P P+  P       LP     + P   +  P   G  GPPG+ G       PGP G  G 
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514

Query: 217  KGDRGQTGEKGPAGPPG---LLGPPGPRGLPGEMGR------------PGPPGPPGPAGN 261
            KG++G TG  GP GPPG   L GPPGP+G  G  G             PGPPGPPG    
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ 1574

Query: 262  PGPSPNSPQGALYSLQPPTDKDNGDS 287
            P P   S            D  NG++
Sbjct: 1575 PLPIQASRTRRNIDASQLLDDGNGEN 1600


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  147 bits (371), Expect = 2e-35
 Identities = 94/223 (42%), Positives = 104/223 (46%), Gaps = 18/223 (8%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPGE 246
           P +    GP GP G  G  G  GP G+ G RG  G+ GPAGPPG +GP   PG  G PG 
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373

Query: 247 MGRPGPPGPPGPAGNPGP-----SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
            G  GP G  GP G  GP     +P SP  A  S  P TD   G    A A       G 
Sbjct: 374 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 433

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTP------GSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PGPRGPPGP G  GP GP G  G P      G QG  GE G  GP G PG  GEEG++ A
Sbjct: 434 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493

Query: 356 TAEGEGVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQ 398
             E  GV  +        ER           D LA P+G  G+
Sbjct: 494 RGEPGGVGPIGPP----GERGAPGNRGFPGQDGLAGPKGAPGE 532



 Score =  140 bits (353), Expect = 2e-33
 Identities = 84/190 (44%), Positives = 96/190 (50%), Gaps = 34/190 (17%)

Query: 196 TGPAGPPG---------QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP-- 244
           TGP GPPG         + GPPGPAG  G++G  G+ GE GP GP G  GPPG  G P  
Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 847

Query: 245 -------GEMGRPGPPGPPGPAGNPGP----SPNSPQGALYSLQPPTDKDNGDSRLASAI 293
                  G+ G  G PGP GP+G PGP        P+GA  +  PP     G +    A 
Sbjct: 848 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP-----GATGFPGA- 901

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ---GLAGERGTVGPSGEPGVKGEE 350
                 G PG  G PGPPGPPGP G  GP G  G     G AGE G  GP+G PG KGE 
Sbjct: 902 --AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 351 GEKAAT-AEG 359
           G+   + AEG
Sbjct: 960 GDDGPSGAEG 969



 Score =  139 bits (351), Expect = 4e-33
 Identities = 85/209 (40%), Positives = 96/209 (45%), Gaps = 57/209 (27%)

Query: 186  AHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPG------------ 233
            A   P +R  TGP GP G  GPPG  G PG+KG++G+ G+KG AG PG            
Sbjct: 817  ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876

Query: 234  ------------LLGPPGPRGLPGEMGRPGPPGP---PGPAGNPGPS-PNSPQGALYSLQ 277
                          GPPG  G PG  GR GPPG    PGP G PGPS  + P+GA     
Sbjct: 877  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936

Query: 278  PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT 337
            PP                    G+ GP GPPG  G PG  GP G  G PG QGLAG+RG 
Sbjct: 937  PPGRAGE--------------PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 982

Query: 338  V---------------GPSGEPGVKGEEG 351
            V               GPSGEPG +G  G
Sbjct: 983  VGLPGQRGERGFPGLPGPSGEPGKQGAPG 1011



 Score =  136 bits (343), Expect = 3e-32
 Identities = 94/250 (37%), Positives = 109/250 (43%), Gaps = 63/250 (25%)

Query: 165 PAPEST---PPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGP-------------- 207
           P P+     P    E  LP A P    +P +   TG AGPPG  GP              
Sbjct: 605 PGPKGANGEPGKAGEKGLPGA-PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663

Query: 208 ----PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
               PGP GPPG  G  G  G  G AG PGL+GP G RG PGE G PG  G  GP G PG
Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 723

Query: 264 -PSPNSPQGALYSLQPPTDK----------DNGDSRLASAIVDTVLAGVPGPRGPP---- 308
            P  + P+GA     PP  +          + G + +A    D    G  GP G P    
Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783

Query: 309 -----GPPGPPGPR---------GPPGPPGTPGSQGLAGERGTVGP------------SG 342
                GP GPPGP          GPPGP G+ G++G  GERG  GP             G
Sbjct: 784 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 843

Query: 343 EPGVKGEEGE 352
           +PG KGE+GE
Sbjct: 844 QPGAKGEQGE 853



 Score =  134 bits (337), Expect = 2e-31
 Identities = 74/170 (43%), Positives = 85/170 (50%), Gaps = 8/170 (4%)

Query: 196 TGPAGPPGQTGPPG-------PAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
           +G  GP GQ G PG       P GPPG +G  G+ G +G  G  G  G PGPRG  GE G
Sbjct: 97  SGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPG 156

Query: 249 RPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
            PG PGPPGP G PGP P         +    D+  G ++L          G  GP GP 
Sbjct: 157 TPGNPGPPGPPGPPGP-PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 215

Query: 309 GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           G PGP G +G PG PG PG  G  G RG  GP G+PG  GE G+     E
Sbjct: 216 GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 265



 Score =  134 bits (337), Expect = 2e-31
 Identities = 79/163 (48%), Positives = 83/163 (50%), Gaps = 11/163 (6%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GPPG   P GPAG  G +GDRG  GEKG  GP G  G PG  G PG  G PGPPGPP
Sbjct: 117 GPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPP 173

Query: 257 GPAGN-----PGPSPNSPQGA-LYSLQPPTDK--DNGDSRLASAIVDTVLAGVPGPRGPP 308
           G  GN      G       GA L  +Q P       G    A A       G PG  G P
Sbjct: 174 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 233

Query: 309 GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           G  GP GPRGPPGPPG PG  G AG+ G  G  G PG +G  G
Sbjct: 234 GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 276



 Score =  133 bits (335), Expect = 3e-31
 Identities = 80/189 (42%), Positives = 91/189 (48%), Gaps = 20/189 (10%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---------GP 240
           P Q    GP G PG+ GP G AGP G+ GD G+ GE G  G  GL G P         GP
Sbjct: 518 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 577

Query: 241 RGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSL-QPPTDKDNGDSRLASAIVD 295
            G PGE GRPGPPGP G  G PG    P P    G      +       G   L     +
Sbjct: 578 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637

Query: 296 TVLAGVPGPRGP------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
           T  AG PGP GP       G PGP G +G PGPPG PG  G  G++G  G +G PG+ G 
Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 697

Query: 350 EGEKAATAE 358
            GE+    E
Sbjct: 698 RGERGFPGE 706



 Score =  131 bits (330), Expect = 1e-30
 Identities = 76/175 (43%), Positives = 84/175 (48%), Gaps = 7/175 (4%)

Query: 184  PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP---AGPPGLLGPPGP 240
            P A   P      GP G  G  GPPGP GP G  G +G  G+ GP   AG PGL GP GP
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 241  RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
               PGE G PG  GP G  G PGP   + Q  +  L P    + G   L     +    G
Sbjct: 953  ---PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL-PGQRGERGFPGLPGPSGEPGKQG 1008

Query: 301  VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
             PG  G  GPPGP GP G  GP G PG +G  G  G  G  G  GVKG+ GE  A
Sbjct: 1009 APGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA 1063



 Score =  131 bits (330), Expect = 1e-30
 Identities = 80/175 (45%), Positives = 87/175 (49%), Gaps = 24/175 (13%)

Query: 196  TGPAGPPGQTGPPGPAGPPGS------KGDRGQTGE------KGPAGPPGLLGPPGPRGL 243
            TGPAG PG+ G PG  GPPG       KGDRG+TG        GP G PG  GP G +G 
Sbjct: 1028 TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1087

Query: 244  PGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
             GE G  GP GP GPAG  G   P  P+G       P     G+  L      T L G+P
Sbjct: 1088 RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP-----GERGLKGHRGFTGLQGLP 1142

Query: 303  GPRGP------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            GP GP       GP GP GPRGPPGP G  G  G  G  G +GP G  G  GE G
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG 1197



 Score =  130 bits (327), Expect = 2e-30
 Identities = 79/190 (41%), Positives = 92/190 (48%), Gaps = 19/190 (10%)

Query: 176 EDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA-------------GPPGSKGDRGQ 222
           +D L   IP     P    PT  A   GQ GP G               GPPG +G  G+
Sbjct: 73  KDCLSPEIPFGECCPIC--PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGE 130

Query: 223 TGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDK 282
            G +G  G  G  G PGPRG  GE G PG PGPPGP G PGP P         +    D+
Sbjct: 131 QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP-PGLGGNFAAQMAGGFDE 189

Query: 283 DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSG 342
             G ++L    V     G  GPRGPPGP G PGP+G  G PG PG  G++G  G  GP G
Sbjct: 190 KAGGAQLG---VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG 246

Query: 343 EPGVKGEEGE 352
            PG  G++GE
Sbjct: 247 PPGKPGDDGE 256



 Score =  128 bits (322), Expect = 9e-30
 Identities = 76/188 (40%), Positives = 87/188 (46%), Gaps = 26/188 (13%)

Query: 197  GPAGPPGQTGPPG---PAGPPGSKG---DRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
            G +GPPG+ G PG   PAGPPG KG   D G +G +GP GP GL G  G  GLPG+ G  
Sbjct: 933  GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER 992

Query: 251  GPPGPPGPAGNPG-------------PSPNSPQGALYSL-------QPPTDKDNGDSRLA 290
            G PG PGP+G PG             P P  P G             P  D   G    A
Sbjct: 993  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA 1052

Query: 291  SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                D    G  G  G PGPPG PGP GP G  G  G  G  G  G  GP+G  G++G +
Sbjct: 1053 GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1112

Query: 351  GEKAATAE 358
            G +    E
Sbjct: 1113 GPRGDKGE 1120



 Score =  127 bits (320), Expect = 2e-29
 Identities = 80/198 (40%), Positives = 94/198 (47%), Gaps = 41/198 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGD---------RGQTGEKGPAGPPGLLGPPGPRGLPG-- 245
           GP+G PG+ G PGP GP G++G          +G  GE G AG  GL G PG RGLPG  
Sbjct: 576 GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635

Query: 246 -EMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDN-------GDSRLASAI 293
            E G  GPPGP GPAG  G    P P+  QG      PP +          G++     +
Sbjct: 636 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGT------------------PGSQGLAGER 335
                 G PG RG PG  G  GPRG PG PGT                  PG QG+ GER
Sbjct: 696 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 755

Query: 336 GTVGPSGEPGVKGEEGEK 353
           G  G +G  G +G+ GEK
Sbjct: 756 GAAGIAGPKGDRGDVGEK 773



 Score =  127 bits (319), Expect = 2e-29
 Identities = 72/167 (43%), Positives = 82/167 (49%), Gaps = 19/167 (11%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           ++ P G  GP G  G PGPAG  G +G RG+ G  GP GPPG  G PG RG PG+ G  G
Sbjct: 466 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 525

Query: 252 PPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPP 311
           P G PG  G  G +   P+GA           NGD             G+PG RG  G P
Sbjct: 526 PKGAPGERGPSGLA--GPKGA-----------NGDPGRPGE------PGLPGARGLTGRP 566

Query: 312 GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           G  GP+G  GP G PG  G  G  G  G  G+PGV G  G K A  E
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 613



 Score =  126 bits (317), Expect = 3e-29
 Identities = 79/179 (44%), Positives = 85/179 (47%), Gaps = 36/179 (20%)

Query: 189  VPRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPP------GLLGPPG 239
            V   R  TG  G PG  GP   PGPAGP G +GDRG+ G +GP GP       G+ GP G
Sbjct: 1054 VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1113

Query: 240  PRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            PRG  GE G PG  G  G  G  G    P P  P G           D G S        
Sbjct: 1114 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG-----------DQGASG------- 1155

Query: 296  TVLAGVPGPRGPPGPPGP---PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
               AG  GPRGPPGP GP    G  G PGP G PG +G +GE G  GP G PG  G  G
Sbjct: 1156 --PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1212



 Score =  125 bits (313), Expect = 1e-28
 Identities = 75/191 (39%), Positives = 87/191 (45%), Gaps = 34/191 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP---- 250
           P GP GPPG  G PGP G  G+ G+ G+ G  GP GP G  GPPG  G  GE G+P    
Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 264

Query: 251 --GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA---GVPGPR 305
             GPPGP G  G PG +P  P    +   P  D   G++       ++      G PGP 
Sbjct: 265 ERGPPGPQGARGFPG-TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 323

Query: 306 GP------------------------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
           GP                        PGP GPPGP GP G PG PG+ G  GE G  G  
Sbjct: 324 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383

Query: 342 GEPGVKGEEGE 352
           G  G +G  GE
Sbjct: 384 GPEGAQGPRGE 394



 Score =  123 bits (308), Expect = 4e-28
 Identities = 80/194 (41%), Positives = 85/194 (43%), Gaps = 57/194 (29%)

Query: 188 PVPRQRRPTGPAGPPGQTGPPGPAGPPGSKG------------------------DRGQT 223
           P PR R   G  G PG  GPPGP GPPG  G                         +G  
Sbjct: 146 PGPRGR--DGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203

Query: 224 GEKGPAGPPGLLGPPGPRGL---PGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPT 280
           G  GP GPPG  G PGP+G    PGE G PG  GP GP G PGP             P  
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-------------PGK 250

Query: 281 DKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGP 340
             D+G+            AG PG  G  GPPGP G RG PG PG PG +G  G  G  G 
Sbjct: 251 PGDDGE------------AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 298

Query: 341 SGE---PGVKGEEG 351
            GE   PGVKGE G
Sbjct: 299 KGEAGAPGVKGESG 312



 Score =  120 bits (302), Expect = 2e-27
 Identities = 82/228 (35%), Positives = 96/228 (42%), Gaps = 62/228 (27%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGP------------------ 231
           P +R P+G AGP G  G PG  G PG  G RG TG  G AGP                  
Sbjct: 530 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 232 ---------PGLLGPPGP---------------------RGLP---GEMGRPGPPGPPGP 258
                    PG++G PGP                     RGLP   GE G  GPPGP GP
Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649

Query: 259 AGNPG----PSPNSPQGALYSLQPPTDKDN-------GDSRLASAIVDTVLAGVPGPRGP 307
           AG  G    P P+  QG      PP +          G++     +      G PG RG 
Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709

Query: 308 PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PG  G  GPRG PG PGT G +G +G  G  G  G PG++G  GE+ A
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGA 757



 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 48/108 (44%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP+G  G +GP GP+GP G  G  G +G+ G  G PG +GPPGPRG  GE G  GPPG
Sbjct: 1144 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1203

Query: 255  PPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             PGP G PG P P     A   L P   ++ G   L     D    G+
Sbjct: 1204 NPGPPGPPGPPGPGIDMSAFAGLGP---REKGPDPLQYMRADQAAGGL 1248



 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 50/136 (36%), Positives = 53/136 (38%), Gaps = 52/136 (38%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P +R   G  G  G  G PGP GP G +G  G  G  GP GPPG +GP         PGP
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1183

Query: 241  RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
             G PG  GR G  GP GP GNPGP                                    
Sbjct: 1184 IGPPGPRGRSGETGPAGPPGNPGP------------------------------------ 1207

Query: 301  VPGPRGPPGPPGPPGP 316
                   PGPPGPPGP
Sbjct: 1208 -------PGPPGPPGP 1216



 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 46/143 (32%), Positives = 49/143 (34%), Gaps = 47/143 (32%)

Query: 224 GEKGPAGPPGLL---GPPGPRGLPGEMGR----PGPPGPPGPAGNPGPSPNSPQGALYSL 276
           GE  P  P  L    G PGP+G  GE G      GP GPPGP                  
Sbjct: 83  GECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQ----------------- 125

Query: 277 QPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERG 336
                                  G  G +GP G  G  G +G PGP G  G  G  G  G
Sbjct: 126 -----------------------GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPG 162

Query: 337 TVGPSGEPGVKGEEGEKAATAEG 359
             GP G PG  G  G  AA   G
Sbjct: 163 PPGPPGPPGPPGLGGNFAAQMAG 185



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 36/89 (40%), Gaps = 23/89 (25%)

Query: 152  EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA 211
            + A  P+ P      P    P+  +         A+ +P    P GP G  G+TGP GP 
Sbjct: 1151 QGASGPAGPSGPRGPPGPVGPSGKDG--------ANGIPGPIGPPGPRGRSGETGPAGPP 1202

Query: 212  GPPGSKGDRGQTGEKGPAGPPGLLGPPGP 240
            G P            GP GPP   GPPGP
Sbjct: 1203 GNP------------GPPGPP---GPPGP 1216


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  147 bits (371), Expect = 2e-35
 Identities = 94/223 (42%), Positives = 104/223 (46%), Gaps = 18/223 (8%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPGE 246
           P +    GP GP G  G  G  GP G+ G RG  G+ GPAGPPG +GP   PG  G PG 
Sbjct: 245 PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304

Query: 247 MGRPGPPGPPGPAGNPGP-----SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
            G  GP G  GP G  GP     +P SP  A  S  P TD   G    A A       G 
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGF 364

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTP------GSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PGPRGPPGP G  GP GP G  G P      G QG  GE G  GP G PG  GEEG++ A
Sbjct: 365 PGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424

Query: 356 TAEGEGVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQ 398
             E  GV  +        ER           D LA P+G  G+
Sbjct: 425 RGEPGGVGPIGPP----GERGAPGNRGFPGQDGLAGPKGAPGE 463



 Score =  140 bits (353), Expect = 2e-33
 Identities = 84/190 (44%), Positives = 96/190 (50%), Gaps = 34/190 (17%)

Query: 196 TGPAGPPG---------QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP-- 244
           TGP GPPG         + GPPGPAG  G++G  G+ GE GP GP G  GPPG  G P  
Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778

Query: 245 -------GEMGRPGPPGPPGPAGNPGP----SPNSPQGALYSLQPPTDKDNGDSRLASAI 293
                  G+ G  G PGP GP+G PGP        P+GA  +  PP     G +    A 
Sbjct: 779 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP-----GATGFPGA- 832

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ---GLAGERGTVGPSGEPGVKGEE 350
                 G PG  G PGPPGPPGP G  GP G  G     G AGE G  GP+G PG KGE 
Sbjct: 833 --AGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 890

Query: 351 GEKAAT-AEG 359
           G+   + AEG
Sbjct: 891 GDDGPSGAEG 900



 Score =  139 bits (351), Expect = 4e-33
 Identities = 85/209 (40%), Positives = 96/209 (45%), Gaps = 57/209 (27%)

Query: 186 AHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPG------------ 233
           A   P +R  TGP GP G  GPPG  G PG+KG++G+ G+KG AG PG            
Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807

Query: 234 ------------LLGPPGPRGLPGEMGRPGPPGP---PGPAGNPGPS-PNSPQGALYSLQ 277
                         GPPG  G PG  GR GPPG    PGP G PGPS  + P+GA     
Sbjct: 808 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867

Query: 278 PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT 337
           PP                    G+ GP GPPG  G PG  GP G  G PG QGLAG+RG 
Sbjct: 868 PPGRAGE--------------PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGI 913

Query: 338 V---------------GPSGEPGVKGEEG 351
           V               GPSGEPG +G  G
Sbjct: 914 VGLPGQRGERGFPGLPGPSGEPGKQGAPG 942



 Score =  136 bits (343), Expect = 3e-32
 Identities = 94/250 (37%), Positives = 109/250 (43%), Gaps = 63/250 (25%)

Query: 165 PAPEST---PPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGP-------------- 207
           P P+     P    E  LP A P    +P +   TG AGPPG  GP              
Sbjct: 536 PGPKGANGEPGKAGEKGLPGA-PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594

Query: 208 ----PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
               PGP GPPG  G  G  G  G AG PGL+GP G RG PGE G PG  G  GP G PG
Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 654

Query: 264 -PSPNSPQGALYSLQPPTDK----------DNGDSRLASAIVDTVLAGVPGPRGPP---- 308
            P  + P+GA     PP  +          + G + +A    D    G  GP G P    
Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714

Query: 309 -----GPPGPPGPR---------GPPGPPGTPGSQGLAGERGTVGP------------SG 342
                GP GPPGP          GPPGP G+ G++G  GERG  GP             G
Sbjct: 715 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 774

Query: 343 EPGVKGEEGE 352
           +PG KGE+GE
Sbjct: 775 QPGAKGEQGE 784



 Score =  134 bits (337), Expect = 2e-31
 Identities = 79/163 (48%), Positives = 83/163 (50%), Gaps = 11/163 (6%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GPPG   P GPAG  G +GDRG  GEKG  GP G  G PG  G PG  G PGPPGPP
Sbjct: 48  GPKGPPG---PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPP 104

Query: 257 GPAGN-----PGPSPNSPQGA-LYSLQPPTDK--DNGDSRLASAIVDTVLAGVPGPRGPP 308
           G  GN      G       GA L  +Q P       G    A A       G PG  G P
Sbjct: 105 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 164

Query: 309 GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           G  GP GPRGPPGPPG PG  G AG+ G  G  G PG +G  G
Sbjct: 165 GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARG 207



 Score =  133 bits (335), Expect = 3e-31
 Identities = 80/189 (42%), Positives = 91/189 (48%), Gaps = 20/189 (10%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---------GP 240
           P Q    GP G PG+ GP G AGP G+ GD G+ GE G  G  GL G P         GP
Sbjct: 449 PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGP 508

Query: 241 RGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSL-QPPTDKDNGDSRLASAIVD 295
            G PGE GRPGPPGP G  G PG    P P    G      +       G   L     +
Sbjct: 509 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568

Query: 296 TVLAGVPGPRGP------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
           T  AG PGP GP       G PGP G +G PGPPG PG  G  G++G  G +G PG+ G 
Sbjct: 569 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGP 628

Query: 350 EGEKAATAE 358
            GE+    E
Sbjct: 629 RGERGFPGE 637



 Score =  132 bits (332), Expect = 6e-31
 Identities = 73/166 (43%), Positives = 83/166 (50%), Gaps = 8/166 (4%)

Query: 200 GPPGQTGPPG-------PAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP 252
           GP GQ G PG       P GPPG +G  G+ G +G  G  G  G PGPRG  GE G PG 
Sbjct: 32  GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN 91

Query: 253 PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           PGPPGP G PGP P         +    D+  G ++L          G  GP GP G PG
Sbjct: 92  PGPPGPPGPPGP-PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           P G +G PG PG PG  G  G RG  GP G+PG  GE G+     E
Sbjct: 151 PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196



 Score =  131 bits (330), Expect = 1e-30
 Identities = 76/175 (43%), Positives = 84/175 (48%), Gaps = 7/175 (4%)

Query: 184 PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP---AGPPGLLGPPGP 240
           P A   P      GP G  G  GPPGP GP G  G +G  G+ GP   AG PGL GP GP
Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 883

Query: 241 RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
              PGE G PG  GP G  G PGP   + Q  +  L P    + G   L     +    G
Sbjct: 884 ---PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGL-PGQRGERGFPGLPGPSGEPGKQG 939

Query: 301 VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            PG  G  GPPGP GP G  GP G PG +G  G  G  G  G  GVKG+ GE  A
Sbjct: 940 APGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA 994



 Score =  131 bits (330), Expect = 1e-30
 Identities = 80/175 (45%), Positives = 87/175 (49%), Gaps = 24/175 (13%)

Query: 196  TGPAGPPGQTGPPGPAGPPGS------KGDRGQTGE------KGPAGPPGLLGPPGPRGL 243
            TGPAG PG+ G PG  GPPG       KGDRG+TG        GP G PG  GP G +G 
Sbjct: 959  TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1018

Query: 244  PGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
             GE G  GP GP GPAG  G   P  P+G       P     G+  L      T L G+P
Sbjct: 1019 RGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEP-----GERGLKGHRGFTGLQGLP 1073

Query: 303  GPRGP------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            GP GP       GP GP GPRGPPGP G  G  G  G  G +GP G  G  GE G
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETG 1128



 Score =  128 bits (322), Expect = 9e-30
 Identities = 76/188 (40%), Positives = 87/188 (46%), Gaps = 26/188 (13%)

Query: 197  GPAGPPGQTGPPG---PAGPPGSKG---DRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
            G +GPPG+ G PG   PAGPPG KG   D G +G +GP GP GL G  G  GLPG+ G  
Sbjct: 864  GDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGER 923

Query: 251  GPPGPPGPAGNPG-------------PSPNSPQGALYSL-------QPPTDKDNGDSRLA 290
            G PG PGP+G PG             P P  P G             P  D   G    A
Sbjct: 924  GFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAA 983

Query: 291  SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                D    G  G  G PGPPG PGP GP G  G  G  G  G  G  GP+G  G++G +
Sbjct: 984  GVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1043

Query: 351  GEKAATAE 358
            G +    E
Sbjct: 1044 GPRGDKGE 1051



 Score =  127 bits (320), Expect = 2e-29
 Identities = 80/198 (40%), Positives = 94/198 (47%), Gaps = 41/198 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGD---------RGQTGEKGPAGPPGLLGPPGPRGLPG-- 245
           GP+G PG+ G PGP GP G++G          +G  GE G AG  GL G PG RGLPG  
Sbjct: 507 GPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566

Query: 246 -EMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDN-------GDSRLASAI 293
            E G  GPPGP GPAG  G    P P+  QG      PP +          G++     +
Sbjct: 567 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGT------------------PGSQGLAGER 335
                 G PG RG PG  G  GPRG PG PGT                  PG QG+ GER
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 686

Query: 336 GTVGPSGEPGVKGEEGEK 353
           G  G +G  G +G+ GEK
Sbjct: 687 GAAGIAGPKGDRGDVGEK 704



 Score =  127 bits (319), Expect = 2e-29
 Identities = 72/167 (43%), Positives = 82/167 (49%), Gaps = 19/167 (11%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           ++ P G  GP G  G PGPAG  G +G RG+ G  GP GPPG  G PG RG PG+ G  G
Sbjct: 397 EQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAG 456

Query: 252 PPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPP 311
           P G PG  G  G +   P+GA           NGD             G+PG RG  G P
Sbjct: 457 PKGAPGERGPSGLA--GPKGA-----------NGDPGRPGE------PGLPGARGLTGRP 497

Query: 312 GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           G  GP+G  GP G PG  G  G  G  G  G+PGV G  G K A  E
Sbjct: 498 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544



 Score =  126 bits (317), Expect = 3e-29
 Identities = 79/179 (44%), Positives = 85/179 (47%), Gaps = 36/179 (20%)

Query: 189  VPRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPP------GLLGPPG 239
            V   R  TG  G PG  GP   PGPAGP G +GDRG+ G +GP GP       G+ GP G
Sbjct: 985  VKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQG 1044

Query: 240  PRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            PRG  GE G PG  G  G  G  G    P P  P G           D G S        
Sbjct: 1045 PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG-----------DQGASG------- 1086

Query: 296  TVLAGVPGPRGPPGPPGP---PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
               AG  GPRGPPGP GP    G  G PGP G PG +G +GE G  GP G PG  G  G
Sbjct: 1087 --PAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPG 1143



 Score =  125 bits (313), Expect = 1e-28
 Identities = 75/191 (39%), Positives = 87/191 (45%), Gaps = 34/191 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP---- 250
           P GP GPPG  G PGP G  G+ G+ G+ G  GP GP G  GPPG  G  GE G+P    
Sbjct: 136 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 195

Query: 251 --GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA---GVPGPR 305
             GPPGP G  G PG +P  P    +   P  D   G++       ++      G PGP 
Sbjct: 196 ERGPPGPQGARGFPG-TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254

Query: 306 GP------------------------PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
           GP                        PGP GPPGP GP G PG PG+ G  GE G  G  
Sbjct: 255 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314

Query: 342 GEPGVKGEEGE 352
           G  G +G  GE
Sbjct: 315 GPEGAQGPRGE 325



 Score =  120 bits (302), Expect = 2e-27
 Identities = 82/228 (35%), Positives = 96/228 (42%), Gaps = 62/228 (27%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGP------------------ 231
           P +R P+G AGP G  G PG  G PG  G RG TG  G AGP                  
Sbjct: 461 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 232 ---------PGLLGPPGP---------------------RGLP---GEMGRPGPPGPPGP 258
                    PG++G PGP                     RGLP   GE G  GPPGP GP
Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580

Query: 259 AGNPG----PSPNSPQGALYSLQPPTDKDN-------GDSRLASAIVDTVLAGVPGPRGP 307
           AG  G    P P+  QG      PP +          G++     +      G PG RG 
Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 308 PGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PG  G  GPRG PG PGT G +G +G  G  G  G PG++G  GE+ A
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGA 688



 Score =  120 bits (300), Expect = 3e-27
 Identities = 76/182 (41%), Positives = 80/182 (43%), Gaps = 42/182 (23%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGE---------------------KGPAGPPG 233
           P G  G PG  G PGP GPPG  G  G  G                      +GP GP G
Sbjct: 79  PRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138

Query: 234 LLGPPGPRGLPGEMGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASA 292
             GPPGP G PG  G  G PG PG  G  GP  P  P G      P    D+G+      
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG-----PPGKPGDDGE------ 187

Query: 293 IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGE---PGVKGE 349
                 AG PG  G  GPPGP G RG PG PG PG +G  G  G  G  GE   PGVKGE
Sbjct: 188 ------AGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGE 241

Query: 350 EG 351
            G
Sbjct: 242 SG 243



 Score = 92.4 bits (228), Expect = 7e-19
 Identities = 48/108 (44%), Positives = 57/108 (52%), Gaps = 4/108 (3%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP+G  G +GP GP+GP G  G  G +G+ G  G PG +GPPGPRG  GE G  GPPG
Sbjct: 1075 PPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPG 1134

Query: 255  PPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             PGP G PG P P     A   L P   ++ G   L     D    G+
Sbjct: 1135 NPGPPGPPGPPGPGIDMSAFAGLGP---REKGPDPLQYMRADQAAGGL 1179



 Score = 82.8 bits (203), Expect = 6e-16
 Identities = 50/136 (36%), Positives = 53/136 (38%), Gaps = 52/136 (38%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P +R   G  G  G  G PGP GP G +G  G  G  GP GPPG +GP         PGP
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGP 1114

Query: 241  RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
             G PG  GR G  GP GP GNPGP                                    
Sbjct: 1115 IGPPGPRGRSGETGPAGPPGNPGP------------------------------------ 1138

Query: 301  VPGPRGPPGPPGPPGP 316
                   PGPPGPPGP
Sbjct: 1139 -------PGPPGPPGP 1147



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 40/126 (31%), Positives = 43/126 (34%), Gaps = 44/126 (34%)

Query: 238 PGPRGLPGEMGR----PGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAI 293
           PGP+G  GE G      GP GPPGP                                   
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQ---------------------------------- 56

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
                 G  G +GP G  G  G +G PGP G  G  G  G  G  GP G PG  G  G  
Sbjct: 57  ------GPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNF 110

Query: 354 AATAEG 359
           AA   G
Sbjct: 111 AAQMAG 116



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 29/89 (32%), Positives = 36/89 (40%), Gaps = 23/89 (25%)

Query: 152  EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA 211
            + A  P+ P      P    P+  +         A+ +P    P GP G  G+TGP GP 
Sbjct: 1082 QGASGPAGPSGPRGPPGPVGPSGKDG--------ANGIPGPIGPPGPRGRSGETGPAGPP 1133

Query: 212  GPPGSKGDRGQTGEKGPAGPPGLLGPPGP 240
            G P            GP GPP   GPPGP
Sbjct: 1134 GNP------------GPPGPP---GPPGP 1147


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  147 bits (371), Expect = 2e-35
 Identities = 83/183 (45%), Positives = 91/183 (49%), Gaps = 21/183 (11%)

Query: 186 AHPVPRQRRPTGPAGPPGQTGPPGP---AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
           A  +P    P GPAGP G+ G PGP    GPPGS+G+ G  GE GP G  G  GP GP G
Sbjct: 796 ARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855

Query: 243 LPGEMGRPGPPGPPGPAGNPGPS-------PNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            PG  G PG PG  G AG+PGP        P+ P G      P      G      A   
Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGV-----PGLKGGRGTQGPPGATGF 910

Query: 296 TVLAGVPGPRGPPGPPGP------PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
              AG  GP GP G PGP      PG  GPPG  G PGS G  G+RG  GP G PG KG+
Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970

Query: 350 EGE 352
            GE
Sbjct: 971 PGE 973



 Score =  136 bits (342), Expect = 4e-32
 Identities = 85/214 (39%), Positives = 100/214 (46%), Gaps = 56/214 (26%)

Query: 195 PTGPAGPPG------QTGPPGPAG------PPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
           P+GP GPPG      + GPPGP G      PPG  G+ G+ G++G  G PG +GP GPRG
Sbjct: 652 PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRG 711

Query: 243 ---------------LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQ---------- 277
                          LPGE G  G  GP GP G+PGPS          LQ          
Sbjct: 712 ERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771

Query: 278 ---PPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPGP------PGPRGPPGPPGTPG 327
              P  D+   G+        +    G+PGP GPPGP GP      PGPRG  GPPG+ G
Sbjct: 772 TPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRG 831

Query: 328 SQGLAGERGTV---------GPSGEPGVKGEEGE 352
           + G  GE G           GP G+PGVKGE GE
Sbjct: 832 NPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE 865



 Score =  135 bits (341), Expect = 6e-32
 Identities = 79/173 (45%), Positives = 88/173 (50%), Gaps = 24/173 (13%)

Query: 195  PTGPAGPPGQTGP---PGPAGPPGSKGD---RGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            P GPAG PG  GP   PG  GPPG +GD    G+ G++GPAGPPG    PG +G PGE G
Sbjct: 919  PPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG---GPGDKGDPGEDG 975

Query: 249  RPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
            +PGP GPPGPAG  G       P     +G      P      G          T   G 
Sbjct: 976  QPGPDGPPGPAGTTGQRGIVGMPGQRGERG-----MPGLPGPAGTPGKVGPTGATGDKGP 1030

Query: 302  PGPRGPP---GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PGP GPP   GP G PGP GP G  GTPG  G  GERG  G  G  G+ G +G
Sbjct: 1031 PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083



 Score =  134 bits (336), Expect = 2e-31
 Identities = 76/173 (43%), Positives = 87/173 (50%), Gaps = 9/173 (5%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKG---DRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P  +   GP GP G  GP GP G PG +G    +G  G++G  G PG  GP GP G+PG 
Sbjct: 317 PGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGS 376

Query: 247 MGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            G PG PG  G AG  G   P  PQG      PP     G   L  AI      G PG +
Sbjct: 377 SGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPV--GSPGLPGAIGTD---GTPGAK 431

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           GP G PG  GP G  GPPG+PG QG  G +G  G  G+PGV G +GE     E
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE 484



 Score =  133 bits (334), Expect = 4e-31
 Identities = 81/185 (43%), Positives = 95/185 (51%), Gaps = 18/185 (9%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---------GPRGLPG 245
           P G +G PG+ G  G AG PG +G  G+ GE GP+GP   +GPP         GP G  G
Sbjct: 619 PKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGP---VGPPGLAGERGEQGPPGPTG 675

Query: 246 EMGRPGPPGPPGPAGNPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTV-LAGVP 302
             G PGPPGPPG  G PG    P  P GA+  L P  ++ N   R    I       G+ 
Sbjct: 676 FQGLPGPPGPPGEGGKPGDQGVPGDP-GAVGPLGPRGERGNPGERGEPGITGLPGEKGMA 734

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA--TAEGE 360
           G  GP GP G PGP G PG  G PG QG+ GERG  G  G  G +G  GEK A  TA  +
Sbjct: 735 GGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND 794

Query: 361 GVQQL 365
           G + L
Sbjct: 795 GARGL 799



 Score =  130 bits (326), Expect = 3e-30
 Identities = 75/174 (43%), Positives = 89/174 (51%), Gaps = 10/174 (5%)

Query: 186 AHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGL---LGPPGP-- 240
           AH +P +  P GP G PG +G PG    PG KG+ G TG +GP GP G     GPPGP  
Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGN---PGMKGEAGPTGARGPEGPQGQRGETGPPGPVG 414

Query: 241 -RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             GLPG +G  G PG  GP G+PG S   P  A     P      G   +     D  + 
Sbjct: 415 SPGLPGAIGTDGTPGAKGPTGSPGTS-GPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP 473

Query: 300 GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G  G  GP G PGP G +GP GPPG  G +G  G+ GTVGP G  G +G  G +
Sbjct: 474 GFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNR 527



 Score =  129 bits (323), Expect = 7e-30
 Identities = 71/171 (41%), Positives = 84/171 (49%), Gaps = 16/171 (9%)

Query: 184  PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            P A   P      GP GP G  GP GP G PG +G  G  G+ G  G  G  GP GP G 
Sbjct: 905  PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG 964

Query: 244  PGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
            PG+ G PG  G PGP G PGP+  + Q  +  + P    + G            + G+PG
Sbjct: 965  PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM-PGQRGERG------------MPGLPG 1011

Query: 304  PRGPP---GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            P G P   GP G  G +GPPGP G PGS G  GE G  GP+G  G  G +G
Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062



 Score =  129 bits (323), Expect = 7e-30
 Identities = 75/175 (42%), Positives = 87/175 (49%), Gaps = 21/175 (12%)

Query: 192  QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            Q  P GP GP G TG  G  G PG +G+RG  G  GPAG PG +GP G  G  G  G  G
Sbjct: 976  QPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVG 1035

Query: 252  PPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            PPG  GP G PGP  P    G      P  D   G+        D   AG+PG +G PG 
Sbjct: 1036 PPGSNGPVGEPGPEGPAGNDGT-----PGRDGAVGERGDRG---DPGPAGLPGSQGAPGT 1087

Query: 311  PGP------------PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            PGP            PG RGP GPPG  G +GL G +G  G  G+ G +G+ G+K
Sbjct: 1088 PGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQK 1142



 Score =  128 bits (322), Expect = 9e-30
 Identities = 82/211 (38%), Positives = 100/211 (47%), Gaps = 29/211 (13%)

Query: 150 LLEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQT---- 205
           +L+ A+  + P    P    TP   N +F              R   G  G PG      
Sbjct: 79  VLDCADPVTPPGECCPVCSQTPGGGNTNF-------------GRGRKGQKGEPGLVPVVT 125

Query: 206 ---GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNP 262
              G PGPAGPPGS+G R   GE+GP G P   GP GP+G+ GE G PG PG PGP G+P
Sbjct: 126 GIRGRPGPAGPPGSQGPR---GERGPKGRP---GPRGPQGIDGEPGVPGQPGAPGPPGHP 179

Query: 263 G-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPG 321
             P P+       +     D+ +G       +  +V  G  GPRGP G  G  G  GP G
Sbjct: 180 SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSV--GPVGPRGPQGLQGQQGGAGPTG 237

Query: 322 PPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           PPG PG  G  G  G+ GP G PG  GE+GE
Sbjct: 238 PPGEPGDPGPMGPIGSRGPEGPPGKPGEDGE 268



 Score =  126 bits (316), Expect = 4e-29
 Identities = 86/188 (45%), Positives = 91/188 (48%), Gaps = 32/188 (17%)

Query: 197 GPAGPPGQTGPPGP---------AGPPGSKGDRGQTGEKGP---AGPPGLLGPPGPRGLP 244
           GP+G PG TGPPG          AG PG KGDRG  GEKG    AG  G  G PGP G P
Sbjct: 747 GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPP 806

Query: 245 ------GEMGRPGP---PGPPGPAGNPGP-SPNSPQGALYSLQP------PTDK----DN 284
                 GE G PGP    GPPG  GNPG    N P GA+    P      P  K    + 
Sbjct: 807 GPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEP 866

Query: 285 GDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP 344
           G    A +     LAG PGP GP G PG  G RG  GPPG  G  G AG  G  GP+G P
Sbjct: 867 GQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAP 926

Query: 345 GVKGEEGE 352
           G  G  GE
Sbjct: 927 GPAGPLGE 934



 Score =  124 bits (311), Expect = 2e-28
 Identities = 80/185 (43%), Positives = 83/185 (44%), Gaps = 30/185 (16%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG---PAGP---PGLLGPPGPRGLPGEM--- 247
           G  G  G  GP G  G PGSKG+ G TG  G   P GP   PG  G  GP+G PG+    
Sbjct: 300 GHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAH 359

Query: 248 GRPGPPGPPGPAGNPGPS-------------------PNSPQGALYSLQPPTDKDNGDSR 288
           G PG PGP GP G PG S                   P  PQG      PP     G   
Sbjct: 360 GMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPV--GSPG 417

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
           L  AI      G  GP G PG  GPPG  GPPG PG  GS G  G RG  G  G PG KG
Sbjct: 418 LPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKG 477

Query: 349 EEGEK 353
           E G K
Sbjct: 478 EAGPK 482



 Score =  123 bits (309), Expect = 3e-28
 Identities = 75/172 (43%), Positives = 86/172 (50%), Gaps = 16/172 (9%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL---GPPGPRGLPG 245
           VP  +   GP G PG  G  GP GPPG +G RG  G+ G  GPPG +   G PG RG PG
Sbjct: 472 VPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPG 531

Query: 246 EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
             G PGP G  G  G  G S   P+G+      P     G+  L  A   T   GV GP 
Sbjct: 532 SDGLPGPKGAQGERGPVGSS--GPKGSQGDPGRP-----GEPGLPGARGLTGNPGVQGPE 584

Query: 306 GPPGPPGPPGPRGPPGPPGT------PGSQGLAGERGTVGPSGEPGVKGEEG 351
           G  GP G PG  G PGPPG+      PGS GL G +G+ G  G+PG  G  G
Sbjct: 585 GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAG 636



 Score =  123 bits (308), Expect = 4e-28
 Identities = 71/166 (42%), Positives = 84/166 (50%), Gaps = 12/166 (7%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG +GPPG AGPPGS G +G TG +G  G PG  G PG +G  G  G PGP G  
Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQ 491

Query: 257 GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG 315
           GP G PG      P+G   ++ PP     G+             G+PGP+G  G  GP G
Sbjct: 492 GPIGPPGEEGKRGPRGDPGTVGPPGPV--GERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549

Query: 316 PRGP---------PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
             GP         PG PG PG++GL G  G  GP G+ G  G  GE
Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595



 Score =  122 bits (305), Expect = 8e-28
 Identities = 78/194 (40%), Positives = 91/194 (46%), Gaps = 18/194 (9%)

Query: 178 FLPDAIPLAHPVPRQ-RRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPG 233
           F  +A P   P P   + P GP G  G+ GP   PG  GPPG  G+RG  G +G  G  G
Sbjct: 475 FKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534

Query: 234 LLGP------------PGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSL-QPP 279
           L GP             GP+G  G+ GRPG PG PG  G  G P    P+G L  L  P 
Sbjct: 535 LPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPG 594

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
            D   G              G+PGP+G  G PG PG  G  G PG  G+ G  GE G  G
Sbjct: 595 EDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSG 654

Query: 340 PSGEPGVKGEEGEK 353
           P G PG+ GE GE+
Sbjct: 655 PVGPPGLAGERGEQ 668



 Score =  120 bits (301), Expect = 2e-27
 Identities = 81/216 (37%), Positives = 88/216 (40%), Gaps = 57/216 (26%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDR------GQTGEKGPAGPPGLLGP----- 237
            +P QR   G  G PG  G PG  GP G+ GD+      G  G  GP G PG  GP     
Sbjct: 997  MPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDG 1056

Query: 238  ----------------PGPRGLPGEMGRPGPPGP---------------PGPAGNPG--- 263
                            PGP GLPG  G PG PGP                GP G PG   
Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG 1116

Query: 264  ----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGP---PGP 316
                P P  P+G           D GD         T L G+PGP GP G  G    PGP
Sbjct: 1117 KRGLPGPQGPRG-----DKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGP 1171

Query: 317  RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
             GP GPPG  G  G  G  G +GP G PGV+G  GE
Sbjct: 1172 FGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGE 1207



 Score =  120 bits (300), Expect = 3e-27
 Identities = 68/158 (43%), Positives = 78/158 (49%), Gaps = 25/158 (15%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  G  G TG PG +GPPGS G  G  G +G  GP G+ G PG  G+PG  G  GP G P
Sbjct: 426 GTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEP 485

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP---PGP 313
           GP G  GP           + PP ++     R           G PG  GPPGP    G 
Sbjct: 486 GPHGIQGP-----------IGPPGEEGKRGPR-----------GDPGTVGPPGPVGERGA 523

Query: 314 PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           PG RG PG  G PG +G  GERG VG SG  G +G+ G
Sbjct: 524 PGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG 561



 Score =  116 bits (291), Expect = 4e-26
 Identities = 88/252 (34%), Positives = 110/252 (43%), Gaps = 37/252 (14%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGD---RGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P  R P GP G  G+ G PGP GP G KGD   RG  G+KG  G  GL G PGP G  GE
Sbjct: 1103 PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE 1162

Query: 247  MGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
             G  G PGP GP G PGP  P+  +G    L P              I    + G  G  
Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGP--------------IGPPGVRGSVGEA 1208

Query: 306  GPPGPPGPPGPRGPPGPPG--TPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
            GP GPPG PGP GPPGPPG  T     + G      P  +P  +  E + A   + +   
Sbjct: 1209 GPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMP--DPLPEFTEDQAAPDDKNKTDP 1266

Query: 364  QLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKMKRGGAQPDGVLAALL 423
             +   LK L+ ++          + + SP+G     A    +LK+     Q     +   
Sbjct: 1267 GVHATLKSLSSQI----------ETMRSPDGSKKHPARTCDDLKLCHSAKQ-----SGEY 1311

Query: 424  GPDPGQKSVDQA 435
              DP Q SV+ A
Sbjct: 1312 WIDPNQGSVEDA 1323



 Score =  114 bits (285), Expect = 2e-25
 Identities = 77/195 (39%), Positives = 89/195 (45%), Gaps = 18/195 (9%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
           +P    P GP GP G  G  G AGP G  G+ G  G  GP G  G  GPPG  G  GE G
Sbjct: 211 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG 270

Query: 249 RPGPPGPPGPAGNPGPS--PNSP--------------QGALYSLQPPTDK-DNGDSRLAS 291
           R G PG  G AG+PG    P +P              +G    +  P  K + G +    
Sbjct: 271 RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG 330

Query: 292 AIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           A+      G+PG RG  GP G PG RG  G PG PG  G  G  G+ G  G PG+KGE G
Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390

Query: 352 EKAATAEGEGVQQLR 366
              A    EG Q  R
Sbjct: 391 PTGARGP-EGPQGQR 404



 Score = 48.9 bits (115), Expect = 9e-06
 Identities = 41/133 (30%), Positives = 53/133 (39%), Gaps = 20/133 (15%)

Query: 300 GVPGPRGPPGPP-------GPPGPRGPP---GPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
           G  G +G PG         G PGP GPP   GP G  G +G  G RG  G  GEPGV G+
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ 169

Query: 350 EGEKAATAE-----GEGVQQLREALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRA 404
            G             +G+ +   A     +    L   +G+      P G  G       
Sbjct: 170 PGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ----- 224

Query: 405 NLKMKRGGAQPDG 417
            L+ ++GGA P G
Sbjct: 225 GLQGQQGGAGPTG 237


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  146 bits (369), Expect = 3e-35
 Identities = 84/177 (47%), Positives = 91/177 (51%), Gaps = 24/177 (13%)

Query: 195 PTGPAGPPG---QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P GPAG PG   ++GP GPAGP G++G  G  GE GP GP G  GPPG  G PG  G PG
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830

Query: 252 ---------PPGPPGPAGNPGPSPN----SPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
                    PPGP GPAG PGP  N      +GA  S  PP     G +    A      
Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPP-----GATGFPGA---AGR 882

Query: 299 AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G PGP G  GPPGPPGP G  G  G  G  G AG  G VGP G PG  GE+G   A
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939



 Score =  145 bits (366), Expect = 7e-35
 Identities = 90/208 (43%), Positives = 99/208 (47%), Gaps = 55/208 (26%)

Query: 186 AHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           A   P  R   GP GP G  GPPG  G PG+KG+ G  G KG AGPPG  GP GP G  G
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 246 EMGRP---------GPP------------GPPGPAGNPGPSPNSPQGALYSLQPPTDKDN 284
            +G P         GPP            GPPGP+GN GP P  P         P  K+ 
Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP-PGPP--------GPAGKEG 905

Query: 285 GDSRLASAIVDTVLAGVPGPRGPPGPPGP------PGPRGPPGPPGTPGSQGLAGERGTV 338
           G         +T  AG PG  GPPGPPGP      PG  GP G PGTPG QG+AG+RG V
Sbjct: 906 GKGPRG----ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVV 961

Query: 339 ---------------GPSGEPGVKGEEG 351
                          GPSGEPG +G  G
Sbjct: 962 GLPGQRGERGFPGLPGPSGEPGKQGPSG 989



 Score =  145 bits (365), Expect = 9e-35
 Identities = 76/169 (44%), Positives = 86/169 (50%), Gaps = 1/169 (0%)

Query: 184  PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            P A   P      GP GP G  GPPGP GP G +G +G  GE GPAG PG +GPPGP G 
Sbjct: 871  PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930

Query: 244  PGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
             GE G PG  GP G  G PGP   + Q  +  L P    + G   L     +    G  G
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL-PGQRGERGFPGLPGPSGEPGKQGPSG 989

Query: 304  PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
              G  GPPGP GP G  GPPG  G +G  G  G+ G  G PG KG+ GE
Sbjct: 990  ASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038



 Score =  144 bits (362), Expect = 2e-34
 Identities = 82/187 (43%), Positives = 94/187 (50%), Gaps = 23/187 (12%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP------RGL 243
           P  R P+GP GP G  GP G +G PG+ G +G TG KG  GP G+ GPPGP      RG 
Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 244 PGEMGRPGPPGPPGPAGNPG----------PSPNSPQGALYSLQPPTDKDN-------GD 286
            GE G  G PGPPG  G PG            P  P G   S  P   K +       G+
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531

Query: 287 SRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
           + L  A   T   G PGP G  GPPGP G  G PGPPG PG++G AG  G  GP G  G 
Sbjct: 532 AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591

Query: 347 KGEEGEK 353
            G+ GE+
Sbjct: 592 PGKAGER 598



 Score =  142 bits (357), Expect = 8e-34
 Identities = 81/182 (44%), Positives = 89/182 (48%), Gaps = 13/182 (7%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTG---PPGPAGPPGSKGDRGQTGEKGPAGPPGLLG 236
           P  +P     P    P G  G  G TG   PPGP GP G  G  G  G KG AGP G  G
Sbjct: 303 PRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRG 362

Query: 237 PPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
             GP+G+ GE G PGP G  GPAGNPG             QP     NG   +A A    
Sbjct: 363 SEGPQGVRGEPGPPGPAGAAGPAGNPGADG----------QPGAKGANGAPGIAGAPGFP 412

Query: 297 VLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
              G  GP+GP GPPGP G  G PG PG+ G  G  GE G VG  G PG  GEEG++ A 
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 357 AE 358
            E
Sbjct: 473 GE 474



 Score =  138 bits (347), Expect = 1e-32
 Identities = 82/189 (43%), Positives = 93/189 (49%), Gaps = 35/189 (18%)

Query: 192  QRRPTGPAGPPGQTGPPGPAG---------------PPGSKGDRGQTGEKGPAGPPGLLG 236
            +R P GP GPPG  GPPG +G                PG+KGDRG+TG  GP G PG  G
Sbjct: 993  ERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052

Query: 237  PPGPRGLPGEMGRPGPPGPPGPAGNPGP----SPNSPQGALYSLQPPTDK----DNGDSR 288
             PGP G  G+ G  G  GP GPAG  GP     P  PQG      P  DK    + GD  
Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG------PRGDKGETGEQGDRG 1106

Query: 289  LASAIVDTVLAGVPGP------RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSG 342
            +      + L G PGP      +GP G  GP GPRGPPG  G PG  GL G  G +GP G
Sbjct: 1107 IKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166

Query: 343  EPGVKGEEG 351
              G  G+ G
Sbjct: 1167 PRGRTGDAG 1175



 Score =  137 bits (345), Expect = 2e-32
 Identities = 79/181 (43%), Positives = 88/181 (48%), Gaps = 24/181 (13%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           P G  GP G+ G  G  GPPG  G  G+ GE+GPAG PG  G PGP G PGE G+PG  G
Sbjct: 603 PPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQG 662

Query: 255 PPGPAGNPGPS-------------------PNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            PG  G PGPS                   P  P+GA  +  P  D   GD+    A   
Sbjct: 663 VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA--NGAPGNDGAKGDAGAPGAPGS 720

Query: 296 ---TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
                L G+PG RG  G PGP G RG  GP G  GS G  G RG  GP G PG  G  G+
Sbjct: 721 QGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGD 780

Query: 353 K 353
           K
Sbjct: 781 K 781



 Score =  134 bits (338), Expect = 1e-31
 Identities = 78/185 (42%), Positives = 92/185 (49%), Gaps = 27/185 (14%)

Query: 196 TGPAGPPGQTGPPGPAGPPGSK---------------GDRGQTGEKGPAGPPGLLGPPGP 240
           TGP GP GQ G PGP GPPG++               G+ G+ GE+G  GPPG +GP G 
Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGK 612

Query: 241 RGLPGEMGRPGPPGP------PGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLA 290
            G  G  G PGP GP       GPAG+PG    P P  P G   + +P      GD    
Sbjct: 613 DGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE--AGKPGEQGVPGDLGAP 670

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                    G PG RG  GPPGP GPRG  G PG  G++G AG  G  G  G PG++G  
Sbjct: 671 GPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730

Query: 351 GEKAA 355
           GE+ A
Sbjct: 731 GERGA 735



 Score =  132 bits (332), Expect = 6e-31
 Identities = 74/172 (43%), Positives = 87/172 (50%), Gaps = 18/172 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP---- 252
           GP GP G+ G PGPAGP GS G+ G+ GE G  G  GL G PG  G  G+ G PGP    
Sbjct: 503 GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQD 562

Query: 253 --PGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
             PGPPGP G  G       P P    G     +P    + G      A+      G  G
Sbjct: 563 GRPGPPGPPGARGQAGVMGFPGPKGAAG-----EPGKAGERGVPGPPGAVGPAGKDGEAG 617

Query: 304 PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            +GPPGP GP G RG  GP G+PG QGL G  G  G +G+PG +G  G+  A
Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669



 Score =  128 bits (322), Expect = 9e-30
 Identities = 89/242 (36%), Positives = 99/242 (40%), Gaps = 67/242 (27%)

Query: 155 ERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGP---A 211
           E  + P  ++P  E  P            P     P  +  TG  GP G TGP GP   A
Sbjct: 77  ETKNCPGAEVPEGECCP----------VCPDGSESPTDQETTGVEGPKGDTGPRGPRGPA 126

Query: 212 GPPGSKGDRGQTGEKGPAGPPGLLGPPG-------------------------------P 240
           GPPG  G  GQ G  GP GPPG  GPPG                               P
Sbjct: 127 GPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP 186

Query: 241 RGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPP-TDKDNGDSRLASAIVDTVL 298
           RGLPG  G PGP G  GP G PG P  + P G      PP  + D+G+            
Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE------------ 234

Query: 299 AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ---------GLAGERGTVGPSGEPGVKGE 349
           AG PG  G  GPPGP G RG PG  G PG +         G  G+ G  GP GEPG  GE
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 350 EG 351
            G
Sbjct: 295 NG 296



 Score =  128 bits (321), Expect = 1e-29
 Identities = 71/157 (45%), Positives = 80/157 (50%), Gaps = 17/157 (10%)

Query: 198 PAGPPGQTGPPGP--AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP 255
           P  P G   P      G  G KGD G  G +GPAGPPG  G PG  GLPG  G PGPPGP
Sbjct: 93  PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGP 152

Query: 256 PGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG 315
           PG  GN  P  +      Y      +K  G   +   +      G  GPRG PGPPG PG
Sbjct: 153 PGLGGNFAPQLS------YGYD---EKSTGGISVPGPM------GPSGPRGLPGPPGAPG 197

Query: 316 PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           P+G  GPPG PG  G +G  G  GP G PG  G++GE
Sbjct: 198 PQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/190 (39%), Positives = 82/190 (43%), Gaps = 32/190 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           P G  G PG+ G  G  GP G  G  G  G+KG +GP G  GP G RG PG+ G PGPPG
Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG 809

Query: 255 PPGPAGNPG----------------------PSPNSPQGALYSLQPPTDKDN----GDSR 288
           P G AG PG                      P P  P G      PP    N    G   
Sbjct: 810 PAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG------PPGPIGNVGAPGAKG 863

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
              +       G PG  G  GPPGP G  GPPGPPG  G +G  G RG  GP+G PG  G
Sbjct: 864 ARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG 923

Query: 349 EEGEKAATAE 358
             G      E
Sbjct: 924 PPGPPGPAGE 933



 Score =  127 bits (318), Expect = 3e-29
 Identities = 82/214 (38%), Positives = 92/214 (42%), Gaps = 38/214 (17%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQ---TGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLG 236
           P  +P     P  +   GP G PG+   +GP GP GPPG  G  G  GE G  G PG  G
Sbjct: 186 PRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERG 245

Query: 237 PPGP---RGLPGEMGRP---------------GPPGPPGPAGNPG-PSPNSPQGALYSLQ 277
           PPGP   RGLPG  G P               G  GP GP G PG P  N   G +    
Sbjct: 246 PPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305

Query: 278 PPTDKDN----GDSRLASAIVDTVLAGVPGPRGPPGPP------------GPPGPRGPPG 321
            P ++      G +        T  AG PGP GP GPP            GP GPRG  G
Sbjct: 306 LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEG 365

Query: 322 PPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           P G  G  G  G  G  GP+G PG  G+ G K A
Sbjct: 366 PQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA 399



 Score =  126 bits (317), Expect = 3e-29
 Identities = 78/194 (40%), Positives = 86/194 (44%), Gaps = 37/194 (19%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           P GP+GP G  GPPG  GP G +G  G+ GE G +GP G  GPPGP G  G+ G  G PG
Sbjct: 180 PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239

Query: 255 PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA--------------- 299
            PG  G PGP           L P      G S L  A  D   A               
Sbjct: 240 RPGERGPPGPQGARGLPGTAGL-PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP 298

Query: 300 ------GVPGPRGPPGPP---------------GPPGPRGPPGPPGTPGSQGLAGERGTV 338
                 G+PG RG PG P               GPPGP GP GPPG PG+ G  GE G  
Sbjct: 299 GQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQ 358

Query: 339 GPSGEPGVKGEEGE 352
           GP G  G +G  GE
Sbjct: 359 GPRGSEGPQGVRGE 372



 Score =  126 bits (316), Expect = 4e-29
 Identities = 79/213 (37%), Positives = 97/213 (45%), Gaps = 41/213 (19%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPP---GPAGPPGSKGDRGQTGEKGPAGPPGLLG 236
           P   P    +P    P G AG PG+ G P   G  GP G++G+RG  GE+G  GPPG  G
Sbjct: 636 PAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695

Query: 237 P---------------------------PGPRGLPGEMGRPGPPGPPGPAGNPGP--SPN 267
           P                           PG +G+PGE G  G PGP G  G+ GP  +  
Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADG 755

Query: 268 SP-----QGALYSLQPP----TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRG 318
           SP     +G    + PP       D G+S  +     T   G PG RG PGPPGP G  G
Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815

Query: 319 PPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           PPG  G PG++G  G+ G  G +G PG  G  G
Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848



 Score =  125 bits (314), Expect = 8e-29
 Identities = 90/240 (37%), Positives = 109/240 (45%), Gaps = 30/240 (12%)

Query: 180  PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
            P   P A   P    P G +G  G+TGP GPAGP G  G RG  G +GP G  G  G  G
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103

Query: 240  PRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             RG+ G  G  G  GPPGP G+PG     P GA     P      G    A A     L 
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPG--EQGPSGASGPAGP-----RGPPGSAGAPGKDGLN 1156

Query: 300  GVPGPRGPPGP------PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G+PGP GPPGP       GP GP GPPGPPG PG    AG   +  P   P  K  +G +
Sbjct: 1157 GLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPS-AGFDFSFLPQ-PPQEKAHDGGR 1214

Query: 354  AATAEGEGVQQLRE-----ALKILAERVLILEHMIGIHDPLASPEGGSGQDAALRANLKM 408
               A+   V + R+      LK L++++          + + SPEG     A    +LKM
Sbjct: 1215 YYRADDANVVRDRDLEVDTTLKSLSQQI----------ENIRSPEGSRKNPARTCRDLKM 1264



 Score =  125 bits (313), Expect = 1e-28
 Identities = 78/185 (42%), Positives = 81/185 (43%), Gaps = 27/185 (14%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTG------EKGPAGPPGLLGPPG---------PR 241
           GP GP G  G PG AG PG KG RG +G      + GPAGP G  G PG         PR
Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR 304

Query: 242 GLPGEMGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIV 294
           GLPGE GRPG PGP G  GN G       P P  P G      P      G    A    
Sbjct: 305 GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGP-----PGFPGAVGAKGEAGPQG 359

Query: 295 DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKA 354
                G  G RG PGPPGP G  GP G PG  G  G  G  G  G +G PG  G  G   
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419

Query: 355 ATAEG 359
               G
Sbjct: 420 PQGPG 424



 Score =  124 bits (312), Expect = 1e-28
 Identities = 72/175 (41%), Positives = 86/175 (49%), Gaps = 30/175 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG------PAGPPGLLGPPGPRGLPGEMG 248
           P G  G  G  GPPGPAGP G +G++G  G  G      PAGPPG  G PG +G+PG++G
Sbjct: 609 PAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLG 668

Query: 249 RPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
            PGP G  G  G PG       P P  P+GA  +  P  D   GD            AG 
Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGA--NGAPGNDGAKGD------------AGA 714

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
           PG    PG  G PG +G PG  G  G  G  G+RG  GP G  G  G++G +  T
Sbjct: 715 PGA---PGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766



 Score =  124 bits (311), Expect = 2e-28
 Identities = 77/191 (40%), Positives = 86/191 (45%), Gaps = 40/191 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG---------------PR 241
           GP G PG+ G PG  GP G++G+ G TG  GP GP G  GPPG               PR
Sbjct: 302 GPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR 361

Query: 242 GLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           G  G  G  G PGPPGPAG  GP+ N         QP     NG   +A A       G 
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPAGNPGADG----QPGAKGANGAPGIAGAPGFPGARGP 417

Query: 302 PGPRGP------------PGPP---------GPPGPRGPPGPPGTPGSQGLAGERGTVGP 340
            GP+GP            PG P         G PGP G  GPPG  G +G  G RG  GP
Sbjct: 418 SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP 477

Query: 341 SGEPGVKGEEG 351
           +G PG  GE G
Sbjct: 478 TGLPGPPGERG 488



 Score =  124 bits (310), Expect = 2e-28
 Identities = 84/199 (42%), Positives = 90/199 (45%), Gaps = 42/199 (21%)

Query: 197 GPAGPPGQTGPPGP---AGPPGSKGDRGQTGEKGPAGPPGL---------LGPPGPRGLP 244
           G  G PG  G PG    AG PG KGDRG  G KG  G PG          +GPPGP G P
Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778

Query: 245 GEMGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKD---NGDSRLASAIV 294
           G+ G  GP GP GP G  G       P P  P G  ++  P  D      G+   A A  
Sbjct: 779 GDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG--FAGPPGADGQPGAKGEPGDAGAKG 836

Query: 295 DTVLAGVPGPRGPPGPPGP---------PGPRGPPGPPGTPGSQGLAGERGTVGPSGE-- 343
           D   AG PGP GP GPPGP          G RG  GPPG  G  G AG  G  GPSG   
Sbjct: 837 D---AGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG 893

Query: 344 ----PGVKGEEGEKAATAE 358
               PG  G+EG K    E
Sbjct: 894 PPGPPGPAGKEGGKGPRGE 912



 Score =  123 bits (308), Expect = 4e-28
 Identities = 73/183 (39%), Positives = 85/183 (46%), Gaps = 37/183 (20%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKG------------------DRGQTGEKGPAGPPG--- 233
           P GP G PG+ G PG AG PG+KG                    GQ G  GP GPPG   
Sbjct: 516 PAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG 575

Query: 234 ---LLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
              ++G PGP+G  GE G+ G  G PGP G  GP+     G   +  PP        R  
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPA--GKDGEAGAQGPPGPAGPAGER-- 631

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                    G  GP G PG  G PGP GPPG  G PG QG+ G+ G  GPSG  G +G  
Sbjct: 632 ---------GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFP 682

Query: 351 GEK 353
           GE+
Sbjct: 683 GER 685



 Score =  122 bits (307), Expect = 5e-28
 Identities = 79/190 (41%), Positives = 89/190 (46%), Gaps = 37/190 (19%)

Query: 195 PTGPAGPPG------QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPG 245
           PTGPAGPPG        G  GP GP GS+G +G  GE GP GP G  GP   PG  G PG
Sbjct: 336 PTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPG 395

Query: 246 EMGRPGPPG------------PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAI 293
             G  G PG            P GP G  GP    P+G   S +P      GD+      
Sbjct: 396 AKGANGAPGIAGAPGFPGARGPSGPQGPGGPP--GPKG--NSGEPGAPGSKGDTGAKGEP 451

Query: 294 VDTVLAGVPGP---------RGPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
               + G PGP         RG PGP   PGPPG RG PG  G PG+ G+AG +G  G  
Sbjct: 452 GPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGER 511

Query: 342 GEPGVKGEEG 351
           G PG  G +G
Sbjct: 512 GSPGPAGPKG 521


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  145 bits (365), Expect = 9e-35
 Identities = 82/175 (46%), Positives = 93/175 (53%), Gaps = 12/175 (6%)

Query: 187 HP-VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           HP VP    P G  GPPG  G  G AGPPG +G  G+ G  GP GP GL G PG  G  G
Sbjct: 634 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 693

Query: 246 EMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDN-GDSRLASAIVDTVLAGVPG 303
             G+PGPPG PG AG PG P P   +G      PP  K + GDS       ++   G+PG
Sbjct: 694 RDGKPGPPGEPGKAGEPGLPGPEGARG------PPGFKGHTGDSGAPGPRGESGAMGLPG 747

Query: 304 PRGPP---GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
             G P   G  GP GP+GP GP G PG  G  G  G  GPSG PG KG +GE  +
Sbjct: 748 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 802



 Score =  138 bits (348), Expect = 9e-33
 Identities = 92/231 (39%), Positives = 108/231 (46%), Gaps = 32/231 (13%)

Query: 157  PSSPDNDLPAPESTPP---TWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGP 213
            P SP    P P  TP    +  E+  P       P      P G  G PG+ G PG  G 
Sbjct: 779  PGSPGE--PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP-GEKGVPGKEGVPGKPGE 835

Query: 214  PGSKGDRGQTGEKGPAGPPGLLGPPG---------------PRGLPGEMGRPGPPGPPGP 258
            PG KG+RG  G KG  GPPG  G PG               P+GLPGE G  GPPGPPG 
Sbjct: 836  PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 895

Query: 259  AGNPGPSPNSPQGALYSLQPPTDKDNG---DSRLASAIVDTVLA------GVPGPRGPPG 309
             G PG    SP  ++ +L+    ++ G   ++RLA  +     A      G PGP GPPG
Sbjct: 896  PGFPGLRGESP--SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 953

Query: 310  PPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360
              G PG  GP G PG PG  GL G  G +GP GE G KG+ G       GE
Sbjct: 954  KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGE 1004



 Score =  128 bits (322), Expect = 9e-30
 Identities = 76/161 (47%), Positives = 84/161 (52%), Gaps = 18/161 (11%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---GPRGLPGEMGRPG 251
           P GP G PG  G  G  G PG  G  G  G+KG AGPPGL GPP   GP+G  GE G  G
Sbjct: 565 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 624

Query: 252 PPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
             G  G  G+PG P    P G   +  PP     G   +A A      AG PG +G PG 
Sbjct: 625 EVGQKGDQGHPGVPGFMGPPG---NPGPP-----GADGIAGA------AGPPGIQGSPGK 670

Query: 311 PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            GPPGP+GP G PG PG +G  G  G  GP GEPG  GE G
Sbjct: 671 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711



 Score =  125 bits (314), Expect = 8e-29
 Identities = 73/183 (39%), Positives = 88/183 (48%), Gaps = 12/183 (6%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRG---QTGEKGPAGPPGLLGPPGPRGLPGE 246
           P +  P GP GPPG  G  G  G PG+ G+ G     G  GP+GPPG +G PG RG PG+
Sbjct: 370 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 429

Query: 247 MGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            G  G  G  G  G+PGP  P    GA     PP    +G+  L  +       G  G R
Sbjct: 430 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDR 489

Query: 306 GPPGPPGPPGPR--------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
           G PG PG PG R        GPPGP G PG +G  G RG  G  G  G  G +G  +  +
Sbjct: 490 GAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLS 549

Query: 358 EGE 360
            G+
Sbjct: 550 PGD 552



 Score =  124 bits (312), Expect = 1e-28
 Identities = 78/183 (42%), Positives = 86/183 (46%), Gaps = 25/183 (13%)

Query: 181 DAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP------AGPPGL 234
           D I  A   P  +   G  GPPG  GP G  G PG +G  G+ G+ GP      AG PGL
Sbjct: 653 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 712

Query: 235 LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIV 294
            GP G RG PG  G  G  G PGP G  G      Q  L    P  D D G         
Sbjct: 713 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL----PGKDGDTG--------- 759

Query: 295 DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT------VGPSGEPGVKG 348
            T   G  GPRGPPG  G PG  G PGP GTPG +G  GE G+      +GP G PG  G
Sbjct: 760 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819

Query: 349 EEG 351
           E+G
Sbjct: 820 EKG 822



 Score =  121 bits (304), Expect = 1e-27
 Identities = 72/174 (41%), Positives = 82/174 (47%), Gaps = 28/174 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           P GP GPPG+ G PG  G PG  G  GQ G KG  G PGL G  GPRG PGE G  G PG
Sbjct: 766 PQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG 825

Query: 255 PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP---GPP 311
             G  G PG             +P    + GD             G+ G +GPP   G P
Sbjct: 826 KEGVPGKPG-------------EPGFKGERGD------------PGIKGDKGPPGGKGQP 860

Query: 312 GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQL 365
           G PG  G  G  G  G QGL GE G VGP G PG  G  G +  +   E +++L
Sbjct: 861 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 914



 Score =  120 bits (302), Expect = 2e-27
 Identities = 76/216 (35%), Positives = 95/216 (43%), Gaps = 54/216 (25%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP------------------- 237
           GP+GPPG  G PG  G PG  G+RG+ G  G  G PG +GP                   
Sbjct: 410 GPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDG 469

Query: 238 ----------PGPRGLPGEMGRPGPPGPPGPAGNPG------PSPNSPQGALYSL----- 276
                     PGP G  G+ G PG PG PG  G+PG      P P+ P G   S      
Sbjct: 470 EPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 529

Query: 277 ------QPPTDKDNGDSRLASAIVDTVLAGVPG--PRGPPGPPGPPGPRGPPGPPGTPGS 328
                 Q P  +D   S L+   ++ +   V    P GPPG PG PG +G  G PG PG 
Sbjct: 530 PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 589

Query: 329 QGLAGERGTVGPSGEP------GVKGEEGEKAATAE 358
           +G  G++G  GP G P      G +G +GE+ A  E
Sbjct: 590 EGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 625



 Score =  106 bits (264), Expect = 5e-23
 Identities = 77/209 (36%), Positives = 85/209 (40%), Gaps = 40/209 (19%)

Query: 171 PPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAG 230
           P    ED LP    L   +  Q    G AG PG+ G  G  G PG  G RG+ G++G  G
Sbjct: 252 PGERGEDGLPGKPGLRGEIGEQ----GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 307

Query: 231 PPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
             GL G  G RG  GE G  GPPG PG      P P  P               G+    
Sbjct: 308 ELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMP---------------GEQGPK 352

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQGLAGERGTVGPS 341
               D  L G PG +G PG  GP GP GPP         G PG  G+ G  G  G  GPS
Sbjct: 353 GEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS 412

Query: 342 ------------GEPGVKGEEGEKAATAE 358
                       G PG  GE GEK A  E
Sbjct: 413 GPPGSVGAPGLRGTPGKDGERGEKGAAGE 441



 Score =  103 bits (256), Expect = 4e-22
 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 35/152 (23%)

Query: 178  FLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP 237
            +L   +P A+    Q RP GP GPPG+ G PG AGP G  G  GQ G +GP+GP   +GP
Sbjct: 929  YLLAQMPPAYMKSSQGRP-GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP---IGP 984

Query: 238  PGPRGLPGEMGRPG-----PPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASA 292
             G RG  G+ G PG       GPPG  G PG             +P   KD         
Sbjct: 985  KGERGAKGDPGAPGVGLRGEMGPPGIPGQPG-------------EPGYAKDG-------- 1023

Query: 293  IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPG 324
                 L G+PGP+G  GP G PG  GPPGPPG
Sbjct: 1024 -----LPGIPGPQGETGPAGHPGLPGPPGPPG 1050



 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 75/202 (37%), Positives = 79/202 (39%), Gaps = 53/202 (26%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGD------RGQTGEKGPAGPPGLLGPPGPRGLPGE---- 246
            G  GPPG  G PG  G PG KG       +G  GE GP GPPG  G PG  GL GE    
Sbjct: 849  GDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 908

Query: 247  ----------------------------------MGRPGPPGPPGPAGNPGPS-----PN 267
                                               GRPGPPGPPG  G PG +     P 
Sbjct: 909  ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG 968

Query: 268  SP-QGALYSLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG--PRGPPGPP 323
             P QG L     P   K    ++         L G  GP G PG PG PG    G PG P
Sbjct: 969  RPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1028

Query: 324  GTPGSQGLAGERGTVGPSGEPG 345
            G  G  G AG  G  GP G PG
Sbjct: 1029 GPQGETGPAGHPGLPGPPGPPG 1050



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 66/183 (36%), Positives = 72/183 (39%), Gaps = 41/183 (22%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGE------------------------------- 225
            GP G PG+ GP GP GPPG  G  G  GE                               
Sbjct: 876  GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 935

Query: 226  ----KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPT 280
                K   G PG  GPPG  GLPG  G  G PG PG  G  GPS P  P+G   +   P 
Sbjct: 936  PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG 995

Query: 281  DKDNGDSRLASAIVDTVLAGVPGPRG--PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTV 338
                G   L   +    + G PG  G    G PG PGP+G  GP G PG  G  G  G  
Sbjct: 996  APGVG---LRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1052

Query: 339  GPS 341
             PS
Sbjct: 1053 DPS 1055



 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 56/171 (32%), Positives = 69/171 (40%), Gaps = 33/171 (19%)

Query: 117  PGFTGSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNE 176
            PGF G   +   M   R     E    LE ++  L A   P+   +    P    P    
Sbjct: 896  PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP---- 951

Query: 177  DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGE--------KGP 228
                   P    +P +  P G  G PGQ G  GP+GP G KG+RG  G+        +G 
Sbjct: 952  -------PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGE 1004

Query: 229  AGPPGLLGPPG--------------PRGLPGEMGRPGPPGPPGPAGNPGPS 265
             GPPG+ G PG              P+G  G  G PG PGPPGP G   PS
Sbjct: 1005 MGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1055



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 55/174 (31%), Positives = 66/174 (37%), Gaps = 36/174 (20%)

Query: 218 GDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP------PGPP---------GPAGNP 262
           G +G   ++  A    +L      GL    G PG       PG P         G AG P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 263 GPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPP------ 311
           G       P +P       +     + G+  L     D    G  GP GPPG P      
Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339

Query: 312 ----------GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
                     GP G +G PG PG PG QG  GE G  GP+G PG KG+EG   A
Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGA 393



 Score = 60.5 bits (145), Expect = 3e-09
 Identities = 49/139 (35%), Positives = 59/139 (42%), Gaps = 21/139 (15%)

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNS-------PQG------ALYSLQPPTDKDNG 285
           GPR  P E    G  G  G  GN    P+S       P+G      A    Q P D+   
Sbjct: 172 GPRTDPWENVDQGAQGACG-RGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQ-RA 229

Query: 286 DSRLASAIVDTV------LAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
           D+R +  +          L G PG RG  G PG PG RG  G  G  G  G  GE G  G
Sbjct: 230 DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPG 289

Query: 340 PSGEPGVKGEEGEKAATAE 358
             G PGV+GE+G++    E
Sbjct: 290 APGFPGVRGEKGDQGEKGE 308



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/67 (40%), Positives = 27/67 (40%), Gaps = 8/67 (11%)

Query: 193  RRPTGPAGPPGQTGPPGPA--------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP 244
            R   GP G PGQ G PG A        GP G  G  G  G  GP GPPG   P       
Sbjct: 1002 RGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFA 1061

Query: 245  GEMGRPG 251
                RPG
Sbjct: 1062 SLAARPG 1068


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  145 bits (365), Expect = 9e-35
 Identities = 82/175 (46%), Positives = 93/175 (53%), Gaps = 12/175 (6%)

Query: 187  HP-VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
            HP VP    P G  GPPG  G  G AGPPG +G  G+ G  GP GP GL G PG  G  G
Sbjct: 1187 HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG 1246

Query: 246  EMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDN-GDSRLASAIVDTVLAGVPG 303
              G+PGPPG PG AG PG P P   +G      PP  K + GDS       ++   G+PG
Sbjct: 1247 RDGKPGPPGEPGKAGEPGLPGPEGARG------PPGFKGHTGDSGAPGPRGESGAMGLPG 1300

Query: 304  PRGPP---GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
              G P   G  GP GP+GP GP G PG  G  G  G  GPSG PG KG +GE  +
Sbjct: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGS 1355



 Score =  138 bits (348), Expect = 9e-33
 Identities = 92/231 (39%), Positives = 108/231 (46%), Gaps = 32/231 (13%)

Query: 157  PSSPDNDLPAPESTPP---TWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGP 213
            P SP    P P  TP    +  E+  P       P      P G  G PG+ G PG  G 
Sbjct: 1332 PGSPGE--PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP-GEKGVPGKEGVPGKPGE 1388

Query: 214  PGSKGDRGQTGEKGPAGPPGLLGPPG---------------PRGLPGEMGRPGPPGPPGP 258
            PG KG+RG  G KG  GPPG  G PG               P+GLPGE G  GPPGPPG 
Sbjct: 1389 PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ 1448

Query: 259  AGNPGPSPNSPQGALYSLQPPTDKDNG---DSRLASAIVDTVLA------GVPGPRGPPG 309
             G PG    SP  ++ +L+    ++ G   ++RLA  +     A      G PGP GPPG
Sbjct: 1449 PGFPGLRGESP--SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 1506

Query: 310  PPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360
              G PG  GP G PG PG  GL G  G +GP GE G KG+ G       GE
Sbjct: 1507 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGE 1557



 Score =  136 bits (343), Expect = 3e-32
 Identities = 79/168 (47%), Positives = 90/168 (53%), Gaps = 17/168 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGE------KGPAGPPGLLGPPGPRG---LPGEM 247
           GP GP G+ GPPG  G  G KGD G  G       +GP GPPG+ GPPGP G   LPGE+
Sbjct: 678 GPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEI 737

Query: 248 GRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV-LAGVPGPR 305
           G PG PGPPGP G PG   PN P G      PP  K     R    +     L G  G +
Sbjct: 738 GFPGKPGPPGPTGPPGKDGPNGPPG------PPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G  G PG  G  G PG PG PG +G  G++G  G  G PG+KG+ GEK
Sbjct: 792 GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEK 839



 Score =  132 bits (332), Expect = 6e-31
 Identities = 75/167 (44%), Positives = 84/167 (50%), Gaps = 40/167 (23%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAG---PPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P  R   G  GPPG  GP GP G   PPG +G RG+ G+ GP G PGLLG  GP   PG 
Sbjct: 662 PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGP---PGP 718

Query: 247 MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
            G PGPPGP G  G PG                                    G PG  G
Sbjct: 719 PGVPGPPGPGGSPGLPGE----------------------------------IGFPGKPG 744

Query: 307 PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           PPGP GPPG  GP GPPG PG++G  GERG  G  G+PG++GE GE+
Sbjct: 745 PPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQ 791



 Score =  130 bits (328), Expect = 2e-30
 Identities = 72/159 (45%), Positives = 83/159 (52%), Gaps = 17/159 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GPPG  GPPG  G PG +G+RG+ G +G  G  GL G PG  G  G+ GRPGP G  
Sbjct: 569 GPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA 628

Query: 257 GPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG 315
           GP G  G   P  P G   S+                       G PGPRG  G PGPPG
Sbjct: 629 GPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQ-------------GAPGPRGHQGAPGPPG 675

Query: 316 PRGPPGP---PGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            RGP GP    G PG QGL G++G +GP G PG+ G +G
Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQG 714



 Score =  128 bits (322), Expect = 9e-30
 Identities = 76/161 (47%), Positives = 84/161 (52%), Gaps = 18/161 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP---GPRGLPGEMGRPG 251
            P GP G PG  G  G  G PG  G  G  G+KG AGPPGL GPP   GP+G  GE G  G
Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177

Query: 252  PPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              G  G  G+PG P    P G   +  PP     G   +A A      AG PG +G PG 
Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPG---NPGPP-----GADGIAGA------AGPPGIQGSPGK 1223

Query: 311  PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
             GPPGP+GP G PG PG +G  G  G  GP GEPG  GE G
Sbjct: 1224 EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264



 Score =  124 bits (312), Expect = 1e-28
 Identities = 78/183 (42%), Positives = 86/183 (46%), Gaps = 25/183 (13%)

Query: 181  DAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP------AGPPGL 234
            D I  A   P  +   G  GPPG  GP G  G PG +G  G+ G+ GP      AG PGL
Sbjct: 1206 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGL 1265

Query: 235  LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIV 294
             GP G RG PG  G  G  G PGP G  G      Q  L    P  D D G         
Sbjct: 1266 PGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL----PGKDGDTG--------- 1312

Query: 295  DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT------VGPSGEPGVKG 348
             T   G  GPRGPPG  G PG  G PGP GTPG +G  GE G+      +GP G PG  G
Sbjct: 1313 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 1372

Query: 349  EEG 351
            E+G
Sbjct: 1373 EKG 1375



 Score =  124 bits (311), Expect = 2e-28
 Identities = 77/191 (40%), Positives = 87/191 (45%), Gaps = 24/191 (12%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPR---GLPG 245
           VP    P G  G PG+ G PG  GPPG  G  G+ G  GP GPPG  G PG R   GLPG
Sbjct: 721 VPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPG 780

Query: 246 EMGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
           + G  G  G  G AG PG       P +P       +     + G+  L     D    G
Sbjct: 781 KPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKG 840

Query: 301 VPGPRGPPGPP----------------GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP 344
             GP GPPG P                GP G +G PG PG PG QG  GE G  GP+G P
Sbjct: 841 EAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP 900

Query: 345 GVKGEEGEKAA 355
           G KG+EG   A
Sbjct: 901 GAKGQEGAHGA 911



 Score =  123 bits (308), Expect = 4e-28
 Identities = 77/202 (38%), Positives = 91/202 (45%), Gaps = 38/202 (18%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRG---QTGEKGPAGPPGLLGPPGPRGLPGE 246
            P +  P GP GPPG  G  G  G PG+ G+ G     G  GP+GPPG +G PG RG PG+
Sbjct: 888  PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 947

Query: 247  MGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRL-----------ASAIV 294
             G  G  G  G  G+PGP  P    GA     PP    +G+  L             A  
Sbjct: 948  DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAAC 1007

Query: 295  DTV---------------------LAGVPGPRGPP--GPPGPPGPRGPPGPPGTPGSQGL 331
              V                     + G PG RG P  G  GPPGP GPPG  G+PGS+GL
Sbjct: 1008 GKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067

Query: 332  AGERGTVGPSGEPGVKGEEGEK 353
             G  G  GP+G  G  G  GE+
Sbjct: 1068 PGFPGPQGPAGRDGAPGNPGER 1089



 Score =  122 bits (306), Expect = 6e-28
 Identities = 83/220 (37%), Positives = 93/220 (42%), Gaps = 51/220 (23%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG---- 245
           P +  P GP GPPG+ GP GP GPPG+KG+ G+ GE G  G PGL G  G +GL G    
Sbjct: 740 PGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE 799

Query: 246 --EMGRPGPPGPPGPAGNPGPS----------------------PNSPQG--ALYSLQPP 279
             E G PG PG PG  G  G                        P  P G     SL  P
Sbjct: 800 KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP 859

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQG 330
             +  G+        D  L G PG +G PG  GP GP GPP         G PG  G+ G
Sbjct: 860 HPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919

Query: 331 LAGERGTVGPS------------GEPGVKGEEGEKAATAE 358
             G  G  GPS            G PG  GE GEK A  E
Sbjct: 920 APGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 959



 Score =  122 bits (305), Expect = 8e-28
 Identities = 80/201 (39%), Positives = 90/201 (44%), Gaps = 44/201 (21%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG-----RPG 251
            G AGPPG +GPPG  G PGS+G  G  G +GPAG  G  G PG RG PG+ G      PG
Sbjct: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104

Query: 252  -------------PPGPPGPAGNPG----------PSPNSPQGALYSLQPP--------- 279
                         PPGPPG  G PG          P     +G      PP         
Sbjct: 1105 DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIA 1164

Query: 280  ----TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP---RGPPGPPGTPGSQGLA 332
                +  + G         D    GVPG  GPPG PGPPG     G  GPPG  GS G  
Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224

Query: 333  GERGTVGPSGEPGVKGEEGEK 353
            G  G  GPSG PG+ GEEG++
Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKE 1245



 Score =  121 bits (304), Expect = 1e-27
 Identities = 72/174 (41%), Positives = 82/174 (47%), Gaps = 28/174 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP GPPG+ G PG  G PG  G  GQ G KG  G PGL G  GPRG PGE G  G PG
Sbjct: 1319 PQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG 1378

Query: 255  PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP---GPP 311
              G  G PG             +P    + GD             G+ G +GPP   G P
Sbjct: 1379 KEGVPGKPG-------------EPGFKGERGD------------PGIKGDKGPPGGKGQP 1413

Query: 312  GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQL 365
            G PG  G  G  G  G QGL GE G VGP G PG  G  G +  +   E +++L
Sbjct: 1414 GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 1467



 Score =  117 bits (294), Expect = 2e-26
 Identities = 70/164 (42%), Positives = 86/164 (52%), Gaps = 18/164 (10%)

Query: 203  GQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNP 262
            G  G PG  G PGS+GD G     G AGPPG  GPPG +G PG  G PG PGP GPAG  
Sbjct: 1025 GDRGAPGIPGSPGSRGDPGI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 1080

Query: 263  GPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG--PRGPPGPPGPPGPRGPP 320
            G +P +P       + P  K    S L+   ++ +   V    P GPPG PG PG +G  
Sbjct: 1081 G-APGNP-----GERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 321  GPPGTPGSQGLAGERGTVGPSGEP------GVKGEEGEKAATAE 358
            G PG PG +G  G++G  GP G P      G +G +GE+ A  E
Sbjct: 1135 GVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 1178



 Score =  117 bits (292), Expect = 3e-26
 Identities = 76/181 (41%), Positives = 89/181 (49%), Gaps = 20/181 (11%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP- 255
            GP+GPPG  G PG  G PG  G+RG   EKG AG  G  GP GPRG PG  G PGPPG  
Sbjct: 928  GPSGPPGSVGAPGLRGTPGKDGERG---EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 984

Query: 256  ----PGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDS-----RLASAIVDTVLA------ 299
                PG  G+PG P P   + A   ++   +   G       R A  I  +  +      
Sbjct: 985  KDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI 1044

Query: 300  GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
            GV GP GP GPPG  G  G  G PG PG QG AG  G  G  GE G  G+ G  +  + G
Sbjct: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104

Query: 360  E 360
            +
Sbjct: 1105 D 1105



 Score =  112 bits (281), Expect = 5e-25
 Identities = 73/189 (38%), Positives = 82/189 (43%), Gaps = 32/189 (16%)

Query: 179  LPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPP 238
            LP    L  P PR     G  GP G+ G PG  G PG +G  G+ G +GP GPPG  G  
Sbjct: 850  LPGTTSLFTPHPRM---PGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906

Query: 239  GPRGLPGEMGRPGPPG------PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASA 292
            G  G PG  G PG PG      P GP G+ G            L+    KD         
Sbjct: 907  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAP---------GLRGTPGKDGE------- 950

Query: 293  IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
                   G  G  G  G PGP GPRG PG PG PG  G  G+ G  G  G PG+ G  G 
Sbjct: 951  ------RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGT 1003

Query: 353  KAATAEGEG 361
            KAA  +  G
Sbjct: 1004 KAACGKVRG 1012



 Score =  103 bits (256), Expect = 4e-22
 Identities = 64/152 (42%), Positives = 75/152 (49%), Gaps = 35/152 (23%)

Query: 178  FLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP 237
            +L   +P A+    Q RP GP GPPG+ G PG AGP G  G  GQ G +GP+GP   +GP
Sbjct: 1482 YLLAQMPPAYMKSSQGRP-GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGP---IGP 1537

Query: 238  PGPRGLPGEMGRPG-----PPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASA 292
             G RG  G+ G PG       GPPG  G PG             +P   KD         
Sbjct: 1538 KGERGAKGDPGAPGVGLRGEMGPPGIPGQPG-------------EPGYAKDG-------- 1576

Query: 293  IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPG 324
                 L G+PGP+G  GP G PG  GPPGPPG
Sbjct: 1577 -----LPGIPGPQGETGPAGHPGLPGPPGPPG 1603



 Score =  101 bits (252), Expect = 1e-21
 Identities = 68/175 (38%), Positives = 78/175 (44%), Gaps = 25/175 (14%)

Query: 195 PTGPAGPPGQTGPPGPAGP-----PGSKG-----------DRGQTGEKGPAGPPGLLGPP 238
           P+GP      T PP P  P     PGS+              G+ GE G AGP GL GP 
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           G  G  G +G PGP G  G  G  GP     +G   SL  P       S+         +
Sbjct: 499 GDIGAIGPVGAPGPKGEKGDVGI-GPFGQGEKGEKGSLGLPGPPGRDGSK--------GM 549

Query: 299 AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG  G PG PG  G RGP GPPG PG  G  G  G  G  GE G +GE+GE+
Sbjct: 550 RGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGER 604



 Score = 99.4 bits (246), Expect = 6e-21
 Identities = 75/202 (37%), Positives = 79/202 (39%), Gaps = 53/202 (26%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGD------RGQTGEKGPAGPPGLLGPPGPRGLPGE---- 246
            G  GPPG  G PG  G PG KG       +G  GE GP GPPG  G PG  GL GE    
Sbjct: 1402 GDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSM 1461

Query: 247  ----------------------------------MGRPGPPGPPGPAGNPGPS-----PN 267
                                               GRPGPPGPPG  G PG +     P 
Sbjct: 1462 ETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPG 1521

Query: 268  SP-QGALYSLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG--PRGPPGPP 323
             P QG L     P   K    ++         L G  GP G PG PG PG    G PG P
Sbjct: 1522 RPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP 1581

Query: 324  GTPGSQGLAGERGTVGPSGEPG 345
            G  G  G AG  G  GP G PG
Sbjct: 1582 GPQGETGPAGHPGLPGPPGPPG 1603



 Score = 91.3 bits (225), Expect = 2e-18
 Identities = 66/183 (36%), Positives = 72/183 (39%), Gaps = 41/183 (22%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGE------------------------------- 225
            GP G PG+ GP GP GPPG  G  G  GE                               
Sbjct: 1429 GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 1488

Query: 226  ----KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPT 280
                K   G PG  GPPG  GLPG  G  G PG PG  G  GPS P  P+G   +   P 
Sbjct: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPG 1548

Query: 281  DKDNGDSRLASAIVDTVLAGVPGPRG--PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTV 338
                G   L   +    + G PG  G    G PG PGP+G  GP G PG  G  G  G  
Sbjct: 1549 APGVG---LRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQC 1605

Query: 339  GPS 341
             PS
Sbjct: 1606 DPS 1608



 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 56/171 (32%), Positives = 69/171 (40%), Gaps = 33/171 (19%)

Query: 117  PGFTGSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNE 176
            PGF G   +   M   R     E    LE ++  L A   P+   +    P    P    
Sbjct: 1449 PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGP---- 1504

Query: 177  DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGE--------KGP 228
                   P    +P +  P G  G PGQ G  GP+GP G KG+RG  G+        +G 
Sbjct: 1505 -------PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGE 1557

Query: 229  AGPPGLLGPPG--------------PRGLPGEMGRPGPPGPPGPAGNPGPS 265
             GPPG+ G PG              P+G  G  G PG PGPPGP G   PS
Sbjct: 1558 MGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/67 (40%), Positives = 27/67 (40%), Gaps = 8/67 (11%)

Query: 193  RRPTGPAGPPGQTGPPGPA--------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP 244
            R   GP G PGQ G PG A        GP G  G  G  G  GP GPPG   P       
Sbjct: 1555 RGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFA 1614

Query: 245  GEMGRPG 251
                RPG
Sbjct: 1615 SLAARPG 1621



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 22/52 (42%), Positives = 28/52 (53%), Gaps = 3/52 (5%)

Query: 310 PPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
           P G  G  G  GP G PG +G   + G +GP G PG KGE+G+      G+G
Sbjct: 479 PAGEKGEMGVAGPMGLPGPKG---DIGAIGPVGAPGPKGEKGDVGIGPFGQG 527


>gi|29725624 collagen, type XXIII, alpha 1 [Homo sapiens]
          Length = 540

 Score =  144 bits (364), Expect = 1e-34
 Identities = 89/203 (43%), Positives = 104/203 (51%), Gaps = 39/203 (19%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG------ 248
           P GP G PGQ G  GP GPPG KG+ G  G+KG  G P   GPPGP+G PG MG      
Sbjct: 212 PAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENG 271

Query: 249 ---RPGPPGPPGPAGNPGPSPNSPQGA--LYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
               PGP G PG  G  G +   P+GA  L   Q  T   + D R+  A     L G PG
Sbjct: 272 VDGAPGPKGEPGHRGTDGAA--GPRGAPGLKGEQGDTVVIDYDGRILDA-----LKGPPG 324

Query: 304 PRGPPGPPGPPG------------------PRGPPGPPGTPGSQGLAGERGTVGPSGEP- 344
           P+GPPGPPG PG                  P+G  G PG PG  GL GE G +G SG P 
Sbjct: 325 PQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPG 384

Query: 345 --GVKGEEGEKAATAEGEGVQQL 365
             G+KGE+GE A+ +  E + QL
Sbjct: 385 ADGLKGEKGESASDSLQESLAQL 407



 Score =  134 bits (336), Expect = 2e-31
 Identities = 74/161 (45%), Positives = 84/161 (52%), Gaps = 7/161 (4%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           P G  G PG  GP G  G PG  G RG  G+ G AGPPG  GPPG RG PG+ G+ GP G
Sbjct: 149 PLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRG 208

Query: 255 PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP 314
             GPAG  G       G +    PP  K  G+  +     D      PGP GP G PG  
Sbjct: 209 AQGPAGPKGEP--GQDGEMGPKGPPGPK--GEPGVPGKKGDDGTPSQPGPPGPKGEPGSM 264

Query: 315 GPRGPPGPPGTPGSQGLAGERGT---VGPSGEPGVKGEEGE 352
           GPRG  G  G PG +G  G RGT    GP G PG+KGE+G+
Sbjct: 265 GPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGD 305



 Score =  126 bits (317), Expect = 3e-29
 Identities = 83/220 (37%), Positives = 103/220 (46%), Gaps = 24/220 (10%)

Query: 188 PVPRQRRP--TGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           P  R+ +P   G  GPPGQ+G  G  GP G  G  G  G KG  G PG  GP G +G  G
Sbjct: 122 PPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDG 181

Query: 246 EMGRPGPPGPPGPAGNPGPS-PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP 304
             G PGPPGPPG  G PG +  + P+GA     P  +                  G  GP
Sbjct: 182 AAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQD--------------GEMGP 227

Query: 305 RGPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE--G 359
           +GPPGP   PG PG +G  G P  PG  G  GE G++GP GE GV G  G K        
Sbjct: 228 KGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGT 287

Query: 360 EGVQQLREALKILAER--VLILEHMIGIHDPLASPEGGSG 397
           +G    R A  +  E+   +++++   I D L  P G  G
Sbjct: 288 DGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQG 327



 Score =  125 bits (313), Expect = 1e-28
 Identities = 71/158 (44%), Positives = 77/158 (48%), Gaps = 10/158 (6%)

Query: 198 PAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAG---PPGLLGPPGPRGLPGEMGRPGPPG 254
           P GPPG+ G PG  G PG  G  G+ G  GP G    PGL GP G +G PG+ G  G  G
Sbjct: 119 PPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQG 178

Query: 255 PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP 314
             G AG PGP    P GA     PP D      R A         G PG  G  GP GPP
Sbjct: 179 QDGAAGPPGPP--GPPGA---RGPPGDTGKDGPRGAQGPAGP--KGEPGQDGEMGPKGPP 231

Query: 315 GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           GP+G PG PG  G  G   + G  GP GEPG  G  GE
Sbjct: 232 GPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGE 269



 Score =  119 bits (297), Expect = 7e-27
 Identities = 66/146 (45%), Positives = 76/146 (52%), Gaps = 6/146 (4%)

Query: 206 GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS 265
           GPPGP GPPG  G  G  GE G  G PG+ G  GP+G  G+ G PGP G  G AG  G S
Sbjct: 321 GPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLS 380

Query: 266 PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGT 325
                  L   +  +  D+    LA  IV+      PGP GPPGPPGP G +G  GP G 
Sbjct: 381 GLPGADGLKGEKGESASDSLQESLAQLIVE------PGPPGPPGPPGPMGLQGIQGPKGL 434

Query: 326 PGSQGLAGERGTVGPSGEPGVKGEEG 351
            G++G  G  G  GPSG PG  G  G
Sbjct: 435 DGAKGEKGASGERGPSGLPGPVGPPG 460



 Score =  117 bits (293), Expect = 2e-26
 Identities = 75/197 (38%), Positives = 86/197 (43%), Gaps = 46/197 (23%)

Query: 200 GPPGQTGPPGPAGPPGSKGDRGQTG------EKGPAGPPGLLGPPGPRGLPGEMGRPG-- 251
           GPPG  GPPGP G PG+KG+ G  G      EKGP G  G  G PGP GL GE G  G  
Sbjct: 321 GPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLS 380

Query: 252 -----------------------------PPGPPGPAGNPGP-------SPNSPQGALYS 275
                                         PGPPGP G PGP        P    GA   
Sbjct: 381 GLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGA--K 438

Query: 276 LQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGER 335
            +     + G S L   +    L G+PG +G  G PG PG  G PGP G  G +   GE+
Sbjct: 439 GEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEK 498

Query: 336 GTVGPSGEPGVKGEEGE 352
           G  G  G  GVKG++GE
Sbjct: 499 GERGVPGRKGVKGQKGE 515



 Score =  100 bits (249), Expect = 3e-21
 Identities = 63/168 (37%), Positives = 77/168 (45%), Gaps = 32/168 (19%)

Query: 177 DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLG 236
           D L +++      P    P GP GP G  G  GP G  G+KG++G +GE+GP+G PG +G
Sbjct: 398 DSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVG 457

Query: 237 PPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
           PPG  GLPG  G  G PG PG  G PGP                +K +   R        
Sbjct: 458 PPGLIGLPGTKGEKGRPGEPGLDGFPGPR--------------GEKGDRSER-------- 495

Query: 297 VLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP 344
              G  G RG PG  G  G +G PGPPG         +   VGP G P
Sbjct: 496 ---GEKGERGVPGRKGVKGQKGEPGPPG-------LDQPCPVGPDGLP 533



 Score = 95.9 bits (237), Expect = 6e-20
 Identities = 55/144 (38%), Positives = 66/144 (45%), Gaps = 21/144 (14%)

Query: 231 PPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRL 289
           P   + PPGP G  G+ GR G PGPPG +G  G P P    G     +P      G+   
Sbjct: 113 PSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDG-----KPGLPGPKGEKGA 167

Query: 290 ASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------------GPPGTPGSQGLAGE 334
                     G  G  GPPGPPGPPG RGPP               GP G PG  G  G 
Sbjct: 168 PGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGP 227

Query: 335 RGTVGPSGEPGVKGEEGEKAATAE 358
           +G  GP GEPGV G++G+    ++
Sbjct: 228 KGPPGPKGEPGVPGKKGDDGTPSQ 251


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  144 bits (363), Expect = 2e-34
 Identities = 79/168 (47%), Positives = 92/168 (54%), Gaps = 21/168 (12%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAG---PPGLLGPPGPRGLPGEMGRPGPP 253
            GP G  G  GPPGPAGP G +G +G +GEKG  G    PG  GPPGP G PG++G PGPP
Sbjct: 1120 GPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPP 1179

Query: 254  GPP---------GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
            GP          GP+G PG P P  P G    +Q P   D  D +         L G PG
Sbjct: 1180 GPQAEKGSEGIRGPSGLPGSPGPPGPPG----IQGPAGLDGLDGKDGK----PGLRGDPG 1231

Query: 304  PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            P GPPG  GPPG +G  G PG PG +G  G+ G  G +G PG +GE G
Sbjct: 1232 PAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPG 1279



 Score =  135 bits (340), Expect = 7e-32
 Identities = 78/169 (46%), Positives = 86/169 (50%), Gaps = 20/169 (11%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEM-- 247
            P  R   GPAGPPG  GPPG  G  G  G  G  G+ G  GPPG  G PG  G PG M  
Sbjct: 1224 PGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGP 1283

Query: 248  -GRPGPP---GPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
             GRPGPP   GPPGP G PGP+  S  G             GD     A  +  LAG+PG
Sbjct: 1284 QGRPGPPGHVGPPGPPGQPGPAGISAVGL-----------KGD---RGATGERGLAGLPG 1329

Query: 304  PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
              GPPG PGPPG  G  G  G  G  G  G  G  GP G+PG  G++G+
Sbjct: 1330 QPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQ 1378



 Score =  125 bits (314), Expect = 8e-29
 Identities = 83/235 (35%), Positives = 102/235 (43%), Gaps = 32/235 (13%)

Query: 187  HP-VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP----- 240
            HP +P  +   G  GPPG TG PG  G PG+ G +G+ G  G  GPPG  G PGP     
Sbjct: 1250 HPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISA 1309

Query: 241  ------------RGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDN 284
                        RGL G  G+PGPPG PGP G PG         P G      PP  K  
Sbjct: 1310 VGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPK-- 1367

Query: 285  GDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP 344
            GD   A         G  G +G  G PG PG  G  GP G PG  G  G  G  GPSG P
Sbjct: 1368 GDPGAAGQ------KGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSP 1421

Query: 345  GVKGEEGEKAATAEGEGVQQL--REALKILAERVLILEHMIGIHDPLASPEGGSG 397
            G+ G  G        + +++   +E +K+  ER+      +     +A+  G  G
Sbjct: 1422 GLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPG 1476



 Score =  125 bits (313), Expect = 1e-28
 Identities = 86/218 (39%), Positives = 95/218 (43%), Gaps = 69/218 (31%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGP------------PGSKGDRGQT------GEKGPAG 230
            +P QR   GP G  G  GPPGP GP            PG +G+RG T      GE GP G
Sbjct: 1028 LPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPG 1087

Query: 231  PPGLLGPPGPRGLP------------GEMGRPGPPGPPGPAGNPGPS----PNSPQGALY 274
             PG  G  GP GLP            GE G PGPPG  G  G PGP+       PQG   
Sbjct: 1088 QPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQG--- 1144

Query: 275  SLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP------GPPGPPGP---------RGP 319
                    + GD             G PGP GPP      G PGPPGP         RGP
Sbjct: 1145 -----NSGEKGDQGFQGQ------PGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGP 1193

Query: 320  ------PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
                  PGPPG PG QG AG  G  G  G+PG++G+ G
Sbjct: 1194 SGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPG 1231



 Score =  121 bits (304), Expect = 1e-27
 Identities = 81/200 (40%), Positives = 93/200 (46%), Gaps = 25/200 (12%)

Query: 184  PLAHPVPRQRRPT----GPAGPPGQTG---PPGPAGPPGSKGDRGQTGEKGPAGPPG--- 233
            P  HP P     T    G  GPPG+ G   PPGP G PG+ G +GQ GEKG AG PG   
Sbjct: 1333 PPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPG 1392

Query: 234  ------LLGPPGP---RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDN 284
                   +GPPGP   RG PG  G  G PG PG  G+ G   N  +   +  Q       
Sbjct: 1393 KSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKM-- 1450

Query: 285  GDSRLA----SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGP 340
             D R+A           +A  PG  GPPG  G PG  G PG PG PG  G  G +G  G 
Sbjct: 1451 FDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGV 1510

Query: 341  SGEPGVKGEEGEKAATAEGE 360
             G PG KGE+G+      GE
Sbjct: 1511 RGLPGTKGEKGDIGIGIAGE 1530



 Score =  119 bits (298), Expect = 5e-27
 Identities = 72/185 (38%), Positives = 81/185 (43%), Gaps = 21/185 (11%)

Query: 183  IPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
            + L  P   + R     G PG  G PG  GPPG  G RG+ G  G  G PG  GP GP G
Sbjct: 995  LSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPG 1054

Query: 243  LPGEMGRPGPP---------------GPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGD 286
             PG +G PG P               G PGP G PG P    P G      P    + G 
Sbjct: 1055 FPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGL-----PGIKGERGY 1109

Query: 287  SRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
            +  A    +    G  G  GPPGP GP G RGP G  G  G QG  G+ G  GP G PG 
Sbjct: 1110 TGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGF 1169

Query: 347  KGEEG 351
             G+ G
Sbjct: 1170 PGKVG 1174



 Score =  118 bits (296), Expect = 9e-27
 Identities = 87/246 (35%), Positives = 95/246 (38%), Gaps = 76/246 (30%)

Query: 184  PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS--------KGDRGQTGEKGPAGPPGLL 235
            P A   P    P G  GPPG  GPPGP G PG         KGDRG TGE+G AG PG  
Sbjct: 1272 PGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQP 1331

Query: 236  GPPGPRGLPGEMGR------------------PGPPGPPGPAGNPGPS--------PNSP 269
            GPPG  G PGE G                   PGP G PG AG  G +        P  P
Sbjct: 1332 GPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGP 1391

Query: 270  --QGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG-------------------- 306
               G++  + PP    + G            L GVPG  G                    
Sbjct: 1392 GKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMF 1451

Query: 307  -------------------PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVK 347
                                PG PGPPG  G PG PG PGS GL G+ G  G  G PGV+
Sbjct: 1452 DERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVR 1511

Query: 348  GEEGEK 353
            G  G K
Sbjct: 1512 GLPGTK 1517



 Score =  117 bits (293), Expect = 2e-26
 Identities = 82/212 (38%), Positives = 91/212 (42%), Gaps = 59/212 (27%)

Query: 190 PRQRRPTGPAGP--------PGQTGPPGPAGPPGSKGDRGQTGE-----KGPAGPPGLLG 236
           P Q  P G  GP        PGQ G PG  GPPG KG +G+ G      +GP G PG  G
Sbjct: 741 PGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPG 800

Query: 237 PPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASA 292
            PG +GLPG  G PGP G  G  G+PG      P  P GA  S  P  D   G       
Sbjct: 801 LPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQ------ 854

Query: 293 IVDTVLAGVPGPRGP-----------------------PGPPG-------PPGPRGP--- 319
              T L G PG +GP                       PG PG        PGP+GP   
Sbjct: 855 ---TGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911

Query: 320 PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           PGPPG PG  GL G  G  G  G+PG+  E G
Sbjct: 912 PGPPGPPGVPGLQGVPGNNGLPGQPGLTAELG 943



 Score =  116 bits (291), Expect = 4e-26
 Identities = 74/193 (38%), Positives = 87/193 (45%), Gaps = 29/193 (15%)

Query: 184 PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGE--------------KGPA 229
           P  H          P+GP G  G  G  GPPGSKG++G  G               +GP 
Sbjct: 318 PCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPK 377

Query: 230 GPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNG 285
           G  G  G  GP GLPG  G  G  G  G  G  G    P  +   G +  + P   K  G
Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQK--G 435

Query: 286 DSRLASAIVDTVLAGVPGPRGPPGPPG------PPGPRGPPGPPGTPGSQGLAGERGTVG 339
           D      +    LAG PGP G PGPPG      P  P GPPGP G  GS G+ G+ G  G
Sbjct: 436 D---PGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGG 492

Query: 340 PSGEPGVKGEEGE 352
             G+PGVKGE+G+
Sbjct: 493 KPGKPGVKGEKGD 505



 Score =  115 bits (288), Expect = 8e-26
 Identities = 78/196 (39%), Positives = 89/196 (45%), Gaps = 35/196 (17%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP---------------AGPPGLLGPPGPR 241
           G  G PG TG PG +G PG +G  G  GEKG                AG PG  GP G +
Sbjct: 691 GDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQ 750

Query: 242 GLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           G P  +GRPG PG PG  G  GP     +G      PP     G      A     + G+
Sbjct: 751 G-PEGVGRPGKPGQPGLPGVQGPP--GLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGL 807

Query: 302 PGPRGPPGPPGPPG------------PRGPPG-----PPGTPGSQGLAGERGTVGPSGEP 344
           PGPRGPPGP G  G            P GPPG     PPG  G QG  G RGT G  G  
Sbjct: 808 PGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPR 867

Query: 345 GVKGEEGEKAATAEGE 360
           G KGE GE +  ++G+
Sbjct: 868 GEKGEPGECSCPSQGD 883



 Score =  110 bits (275), Expect = 3e-24
 Identities = 75/203 (36%), Positives = 88/203 (43%), Gaps = 43/203 (21%)

Query: 197 GPAGPPGQTGPPGPA--GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           GP+G  G+ GPPG    G  G  G+RG  G+KG AG PG  G PG  G PG  G PG  G
Sbjct: 653 GPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQG 712

Query: 255 PPGP---------------------AGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASA 292
           P GP                     AG PG P P   QG     +P      G   +   
Sbjct: 713 PAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGP 772

Query: 293 IVDTVLAGVPGP-----RGPPGPPGP---------PGPRGPPGPPGTPGSQGLAGERGTV 338
                + G PGP     +GP G PG          PGPRGPPGP G  G+QG  G +G  
Sbjct: 773 PGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGAT 832

Query: 339 GPSGEPGVK-----GEEGEKAAT 356
           GP G PG       G +G++  T
Sbjct: 833 GPVGPPGASVSGPPGRDGQQGQT 855



 Score =  108 bits (269), Expect = 1e-23
 Identities = 85/258 (32%), Positives = 97/258 (37%), Gaps = 97/258 (37%)

Query: 196 TGPAGPPG--QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG----------- 242
           +G  G PG    G PG AG PG KG++G  GE GPAG PG  GP GP G           
Sbjct: 575 SGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEP 634

Query: 243 ----------------LPGEMGRPGPPGPP--------------------GPAGNPG--- 263
                           LPG  G  G PGPP                    G AGNPG   
Sbjct: 635 CPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPG 694

Query: 264 -------PSPNSPQGALYSLQPPTDKDNGDS---RLASAIVDTV-LAGVPGPRGPPGP-- 310
                  P  +   G      P  +K +G +    L   + D     G PGP+G  GP  
Sbjct: 695 TPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEG 754

Query: 311 ---------------------------PGPP-----GPRGPPGPPGTPGSQGLAGERGTV 338
                                      PGPP     GP+G PG PG PG QGL G RG  
Sbjct: 755 VGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPP 814

Query: 339 GPSGEPGVKGEEGEKAAT 356
           GP+GE G +G  G K AT
Sbjct: 815 GPTGEKGAQGSPGVKGAT 832



 Score =  102 bits (253), Expect = 9e-22
 Identities = 94/303 (31%), Positives = 108/303 (35%), Gaps = 124/303 (40%)

Query: 164  LPAPESTP-PTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQT--GPPGP---------A 211
            LP P   P PT  +         A   P  +  TGP GPPG +  GPPG           
Sbjct: 807  LPGPRGPPGPTGEKG--------AQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLR 858

Query: 212  GPPGSKGDRGQTGEKG------------------------------PAGPPGLLGPPGPR 241
            G PG KG RG+ GE G                              P GPPG+ GPPGP 
Sbjct: 859  GTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPP 918

Query: 242  GLPGEMGRPGPPGPPGPAG----------------------------NPG---------- 263
            G+PG  G PG  G PG  G                            +PG          
Sbjct: 919  GVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGD 978

Query: 264  ------PSPNSPQGALYSLQPPT------DKDNGDSRLASAIVDTVLAGVPGPRGPP--- 308
                  P  ++      SL+ P       D   GD     +       G+PGP G P   
Sbjct: 979  QGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGS------PGLPGPPGLPGQR 1032

Query: 309  ---------GPPGPPGPRGPPGPP---GTPGSQGLAGER---GTVGPSGEPGVKGEEGEK 353
                     G PGPPGP GPPG P   G+PG  GL GER   G  G  GEPG  G+ G  
Sbjct: 1033 GEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYP 1092

Query: 354  AAT 356
             AT
Sbjct: 1093 GAT 1095



 Score =  100 bits (249), Expect = 3e-21
 Identities = 77/218 (35%), Positives = 90/218 (41%), Gaps = 53/218 (24%)

Query: 159 SPDNDLPAPESTPPTWNEDFL--PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS 216
           SPD  L   E       E     P  +P +     Q+   G  G  G  G PG  G PG 
Sbjct: 365 SPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGE 424

Query: 217 ---KGDRGQTGEKGPAGPPGLLGPPGPRGLPGE--MGRPGPPGPPGPAGNPGPSPNSPQG 271
               G +GQ G+ G  GP GL G PGP GLPG   +G PG PG PG  G PGP       
Sbjct: 425 ICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG--GPPGPK------ 476

Query: 272 ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPP-------- 323
                      D G S            G+PG  GP G PG PG +G  G P        
Sbjct: 477 ----------GDKGSS------------GIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLP 514

Query: 324 -------GTPGSQGLAGERGTVGPS-GEPGVKGEEGEK 353
                  G PG  G  GE G   P+ G+PG++G +GEK
Sbjct: 515 EGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEK 552



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 75/243 (30%), Positives = 93/243 (38%), Gaps = 73/243 (30%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQ------------------TGEKGPAGP 231
           P  +   G +G PG+ GP G  G PG KG++G                    G+ GP G 
Sbjct: 473 PGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGE 532

Query: 232 PG----LLGPPGPRGLPGEMGRP----------------------------GPPGPP--- 256
           PG      G PG +G+ GE G P                            G PG P   
Sbjct: 533 PGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRA 592

Query: 257 ---------------GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
                          GPAG+PG P P  P G   +   P +     S L     D  +  
Sbjct: 593 GVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDG--DVRVVA 650

Query: 301 VPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360
           +PGP G  G PGPPG  G PG  G  G +GL G++G  G  G+PG  G  G    + E  
Sbjct: 651 LPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGE-P 708

Query: 361 GVQ 363
           GVQ
Sbjct: 709 GVQ 711



 Score = 91.7 bits (226), Expect = 1e-18
 Identities = 82/247 (33%), Positives = 95/247 (38%), Gaps = 65/247 (26%)

Query: 157  PSSPDNDLPAPESTPPTWNEDFL----PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAG 212
            P  P  D  A +  PP   + F     P   P A     Q    G AG PG  G  G  G
Sbjct: 1340 PGEPGTDGAAGKEGPPG-KQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMG 1398

Query: 213  PPGSKGDRGQTGEK---GPAGPPGLLGPPGPRG--------------------------- 242
            P G  G  G+ G     GP+G PGL G PG  G                           
Sbjct: 1399 PVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYY 1458

Query: 243  -----LPGEM----GRPGPPGPPGPAGNPGPSPNSP----------QGALYSLQ--PPTD 281
                  P EM    GRPGPPG  G  G PG +P SP          +  L  ++  P T 
Sbjct: 1459 TSRMQFPMEMAAAPGRPGPPGKDGAPGRPG-APGSPGLPGQIGREGRQGLPGVRGLPGTK 1517

Query: 282  KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
             + GD       +   +AG  G  GPPGP GPPG  G  G  G  G QG+ G  G  GP 
Sbjct: 1518 GEKGD-------IGIGIAGENGLPGPPGPQGPPG-YGKMGATGPMGQQGIPGIPGPPGPM 1569

Query: 342  GEPGVKG 348
            G+PG  G
Sbjct: 1570 GQPGKAG 1576



 Score = 85.1 bits (209), Expect = 1e-16
 Identities = 66/202 (32%), Positives = 75/202 (37%), Gaps = 74/202 (36%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPG------------------SKGDRGQTGEKGPAG 230
            V  QR   G     G+ G  G  G PG                  ++GD  + G+ G  G
Sbjct: 960  VQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSE-GDPGCVG 1018

Query: 231  PPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
             PGL   PGP GLPG+ G  GPPG  G  G PGP           + PP           
Sbjct: 1019 SPGL---PGPPGLPGQRGEEGPPGMRGSPGPPGP-----------IGPP----------- 1053

Query: 291  SAIVDTVLAGVPGPRGP---------------------PGPPGPPGPRGPPGPPGTPGSQ 329
                     G PG  G                      PGPPG PG  G  GPPG PG +
Sbjct: 1054 ---------GFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIK 1104

Query: 330  GLAGERGTVGPSGEPGVKGEEG 351
            G  G  G+ G  GEPG  G EG
Sbjct: 1105 GERGYTGSAGEKGEPGPPGSEG 1126



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 43/103 (41%), Positives = 49/103 (47%), Gaps = 18/103 (17%)

Query: 194  RPTGPAGP--PGQTGPPGPAGPPGSKGDRGQTGEKGP-----AGPPGLLGPPGPRGLPG- 245
            RP  P  P  PGQ G  G  G PG +G  G  GEKG      AG  GL GPPGP+G PG 
Sbjct: 1486 RPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY 1545

Query: 246  ----------EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQP 278
                      + G PG PGPPGP G PG + +      +   P
Sbjct: 1546 GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMP 1588



 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 35/74 (47%), Positives = 38/74 (51%), Gaps = 7/74 (9%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G AG  G  GPPGP GPPG  G  G TG  G  G PG+ GPPGP      MG+PG  G  
Sbjct: 1526 GIAGENGLPGPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGP------MGQPGKAGHC 1578

Query: 257  GPAGNPGPSPNSPQ 270
             P+   G  P   Q
Sbjct: 1579 NPSDCFGAMPMEQQ 1592



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 23/76 (30%)

Query: 307 PPGPPGPPGPRGPPGPPGTPGSQGLAG--------------------ER---GTVGPSGE 343
           P GP G  G RG PGPPG+ G +G  G                    E+   G +GPSG 
Sbjct: 332 PSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGL 391

Query: 344 PGVKGEEGEKAATAEG 359
           PG  GE+G+K    +G
Sbjct: 392 PGSTGEKGQKGEKGDG 407



 Score = 37.7 bits (86), Expect = 0.021
 Identities = 27/74 (36%), Positives = 29/74 (39%), Gaps = 13/74 (17%)

Query: 195  PTGPAGPPGQ-----TGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P GP GPPG      TGP G  G PG     G  GQ G+ G   P    G      +P E
Sbjct: 1536 PPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFG-----AMPME 1590

Query: 247  MGRPGPPGPPGPAG 260
               P      GP G
Sbjct: 1591 QQYPPMKTMKGPFG 1604



 Score = 31.6 bits (70), Expect = 1.5
 Identities = 20/61 (32%), Positives = 22/61 (36%)

Query: 310 PPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREAL 369
           PP   G R         G +G  GERG  GP G  G KG  G        +   Q  E  
Sbjct: 317 PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGP 376

Query: 370 K 370
           K
Sbjct: 377 K 377


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  142 bits (358), Expect = 6e-34
 Identities = 91/231 (39%), Positives = 109/231 (47%), Gaps = 45/231 (19%)

Query: 187 HPVPRQRRP---TGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
           H +P +  P   T   GPPG+ GPPGP GPPG  G  G  G++GP GPP   GPPGP G 
Sbjct: 253 HELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP---GPPGPAGE 309

Query: 244 PGEMGRPGPPGPP------GPAGNPG----------PSPNSPQGALYSLQPPTDKDNGDS 287
           PG+ G PG PG P      GP G+PG          P     +G      P      G +
Sbjct: 310 PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 369

Query: 288 RLASAIVDTVLAGVPGPRGPPGPPGPPGPRG---------------PPGPPGTPGSQGLA 332
            L   +      G PG RGPPGPPGPPGPRG               PPG  G PG  G+ 
Sbjct: 370 GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 429

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAE-GE-------GVQQLREALKILAER 375
           G +G  G  GEPG +G +GE+    E GE       G Q LR    I+ ++
Sbjct: 430 GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 480



 Score =  126 bits (316), Expect = 4e-29
 Identities = 71/169 (42%), Positives = 91/169 (53%), Gaps = 10/169 (5%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG---EKGPAGPPGLLGPPGPRGLPGE 246
           P ++   G  G  G+ G  G  GPPG++G RG TG   +KG  G  GL G PGP+GLPG 
Sbjct: 441 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 500

Query: 247 MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
            G  G  GPPG AG  G         +  L  P     GD+ L        + G+PG +G
Sbjct: 501 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP----KGDTGLPGVDGRDGIPGMPGTKG 556

Query: 307 PPGPPGPPGP---RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            PG PGPPG    +G PG PG PG++G+AGE+G+ G  G+PG  G  G+
Sbjct: 557 EPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 605



 Score =  125 bits (313), Expect = 1e-28
 Identities = 79/204 (38%), Positives = 97/204 (47%), Gaps = 20/204 (9%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G +G PGQ GPPG  GP G +G  G  GE GP G PGL G  G  G PG  G PGPPG P
Sbjct: 601 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 660

Query: 257 GPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           G  G+ G    P P   QGA          + G++     + D    G+PGP+G  G PG
Sbjct: 661 GMKGDRGVVGEPGPKGEQGA--------SGEEGEAGERGELGD---IGLPGPKGSAGNPG 709

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREALKIL 372
            PG RGP G  G PG +G  G  G  G  GE G  G  G +         Q +++    +
Sbjct: 710 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQ----V 765

Query: 373 AERVLILEHMIGIHDPLASPEGGS 396
             RV I EH   +   L  P+ G+
Sbjct: 766 CMRV-IQEHFAEMAASLKRPDSGA 788



 Score =  122 bits (307), Expect = 5e-28
 Identities = 70/155 (45%), Positives = 77/155 (49%), Gaps = 4/155 (2%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG  G  G  GPPG  G +G  G +G  G PGL GP G  GLPG  GR G PG P
Sbjct: 493 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G PG  P  P  A     P      G   +A     T   G PG  G  G  G PG 
Sbjct: 553 GTKGEPG-KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST---GAPGKPGQMGNSGKPGQ 608

Query: 317 RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           +GPPG  G  G QGL G RG +GP G PG+ G+ G
Sbjct: 609 QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLG 643



 Score =  121 bits (304), Expect = 1e-27
 Identities = 76/207 (36%), Positives = 87/207 (42%), Gaps = 44/207 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  G PG  G PGP G PG KGDRG  GE GP G  G  G  G  G  GE+G  G PGP 
Sbjct: 643 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702

Query: 257 GPAGNPG----------------------PSPNSPQG-----ALYSLQPPTDKDNGDSRL 289
           G AGNPG                      P P   QG      L  +Q P  +   D  +
Sbjct: 703 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 762

Query: 290 ASAIV-----------------DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA 332
               +                 D+   G+PG  GPPGPPGPPG  G PG  G  G  G+ 
Sbjct: 763 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 822

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEG 359
           G  G +G  G  G  GE+GE+     G
Sbjct: 823 GPPGALGLRGPKGDLGEKGERGPPGRG 849



 Score =  111 bits (278), Expect = 1e-24
 Identities = 79/195 (40%), Positives = 86/195 (44%), Gaps = 16/195 (8%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGP------------PGQTGPPGPAGPPGSKGDRGQTGEKG 227
           P  +P A     QR P G AGP            PG  GP G  G PG  G  G  G  G
Sbjct: 494 PQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPG 553

Query: 228 PAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGP--SPNSPQGALYSLQPPTDKDNG 285
             G PG  GPPG  GL G  G PG PG  G AG  G   +P  P     S +P      G
Sbjct: 554 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 613

Query: 286 DSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPG 345
           +             G  GP G PG PG  G  G PG PG PG  GL G +G  G  GEPG
Sbjct: 614 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 673

Query: 346 VKGEEGEKAATAEGE 360
            KGE+G  A+  EGE
Sbjct: 674 PKGEQG--ASGEEGE 686



 Score =  106 bits (264), Expect = 5e-23
 Identities = 84/230 (36%), Positives = 90/230 (39%), Gaps = 70/230 (30%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA 211
           EA ER    D  LP P+ +     E             P  R P G  G PG  GP GP 
Sbjct: 686 EAGERGELGDIGLPGPKGSAGNPGE-------------PGLRGPEGSRGLPGVEGPRGPP 732

Query: 212 GPPGSKGDRGQTGEKGPAGPPG--------------------------LLGPP-GPRGLP 244
           GP G +G++G TG  G  GPPG                          L  P  G  GLP
Sbjct: 733 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792

Query: 245 GEMGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTD---------KDNGDSR 288
           G  G PGPPGPPG  G PG       P    P GAL    P  D            G + 
Sbjct: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 852

Query: 289 LASAIVDTVLAGVPGP-----------RGPPGPPGPPGPRGPPGPPGTPG 327
           L  AI    L G PGP           RGPPG  G PG  GPPGPPG PG
Sbjct: 853 LPGAIG---LPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/102 (36%), Positives = 40/102 (39%), Gaps = 25/102 (24%)

Query: 168 ESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPP--GQTGPPGPAGPPGSKGDRGQTGE 225
           E  PP    + LP AI L           G  GP   G+ G  G  GPP           
Sbjct: 842 ERGPPGRGPNGLPGAIGLP----------GDPGPASYGRNGRDGERGPP----------- 880

Query: 226 KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGP-AGNPGPSP 266
            G AG PG+ GPPGP GLPG           G  A N GP P
Sbjct: 881 -GVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  142 bits (358), Expect = 6e-34
 Identities = 86/200 (43%), Positives = 97/200 (48%), Gaps = 26/200 (13%)

Query: 172  PTWNEDF-----LPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS-----KGDRG 221
            PT  E F     LP AI     +P Q    GP G  G  G PGP GPPGS     KGD+G
Sbjct: 1217 PTGIEGFPGPPGLPGAI-----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG 1271

Query: 222  QTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-------PSPNSPQGALY 274
              G  GP GPPG  G  GP   PG +G PG PG PGP G+PG              G L 
Sbjct: 1272 SMGHPGPKGPPGTAGDMGP---PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 275  SLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAG 333
            S+ PP      G   +        +  +PG  GPPG PG PG +G PGPPG PG+ G  G
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 334  ERGTVGPSGEPGVKGEEGEK 353
             RG  G  G+PG  G  GEK
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEK 1408



 Score =  132 bits (333), Expect = 5e-31
 Identities = 78/174 (44%), Positives = 89/174 (51%), Gaps = 29/174 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR----P 250
           P G  G PG  GP GPAGPPG  G +G+ G +G  G PG  GPPG  G  GE+      P
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGPPGP G+PGP    P G   SL    D                  G+PGP G PG 
Sbjct: 656 GPPGPPGPPGHPGPQ--GPPGIPGSLGKCGDP-----------------GLPGPDGEPGI 696

Query: 311 PG-----PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           PG     PPGP+G  G PGT GS G  G+ G  G  G+PG+ G +GE A    G
Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG 750



 Score =  127 bits (318), Expect = 3e-29
 Identities = 91/232 (39%), Positives = 101/232 (43%), Gaps = 70/232 (30%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P    P GP G PG  G PG  G PG  GD G  G KG  GPPG+ GP         PGP
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 241  RGLPGEMGRPGPPG-------------PPGPAGNPGP--------SPNSP-----QGALY 274
             G+ G+ GR G PG             PPGP GNPG         +P  P     +GA+ 
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 275  SLQP--PTDKDN--GDSRLASAIV--DTVLAGVPGPRGPPGPPGPPGP------------ 316
               P  PT  +   G   L  AI+   T   G PG RG PG PGPPGP            
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 317  -----RGPPGPPGT------------PGSQGLAGERGTVGPSGEPGVKGEEG 351
                  GP GPPGT            PG+ GL G RG  G  G PGVKGE+G
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322



 Score =  126 bits (316), Expect = 4e-29
 Identities = 81/189 (42%), Positives = 87/189 (46%), Gaps = 38/189 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG----PAGPPGLLGPPGPRGLPGEMGRPGP 252
           G  G PG TG PG  G PG++GD G  GEKG    P G  G+ G PG RG PG  G  G 
Sbjct: 511 GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 253 PGPPGPAGNPGP--------------------SPNSPQGALYSLQPPTDKDNGDSRLASA 292
           PG PG  G PGP                    SP SP G      PP     G+  L   
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAGPPGYGPQGEPGLQGT 629

Query: 293 IVDTVLAGVPG---PRG----------PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  G PG   PRG          PPGPPGPPG  GP GPPG PGS G  G+ G  G
Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 340 PSGEPGVKG 348
           P GEPG+ G
Sbjct: 690 PDGEPGIPG 698



 Score =  124 bits (311), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 84/187 (44%), Gaps = 23/187 (12%)

Query: 197  GPAGPPGQT-----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            G  G PG +     GPPGP G PG  GD G+ GE G  GPPG LGP GP G PG  G PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 252  PPGPPGPAGNPG----------PSPNSPQG--------ALYSLQPPTDKDNGDSRLASAI 293
             PG PGP G+ G          P    P G            ++    +D          
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 294  VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
               +L   PGPRG PG  G  G RG PG PG PG +G  G+ G  GP+G  G  G  G  
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 354  AATAEGE 360
             A   G+
Sbjct: 1231 GAIIPGQ 1237



 Score =  122 bits (306), Expect = 6e-28
 Identities = 77/200 (38%), Positives = 96/200 (48%), Gaps = 40/200 (20%)

Query: 192  QRRPTGPAGPPG-----QTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            +R  TGP G PG     ++G PG  G PG    +G+ G  G++G  G PG+LGPPG  G+
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890

Query: 244  PGEMGRPGPPGPPGPAGNPG----------PSPNSPQGALYSLQPPTDKDN-GDSRLASA 292
             G MG PG  GPPGP GNPG          P     +G   +     DK N G S ++  
Sbjct: 891  IGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHV 950

Query: 293  IVD---------------------TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            I D                       + G+ G +G PGP GPPGPRG  G  G PG  GL
Sbjct: 951  IGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL 1010

Query: 332  AGERGTVGPSGEPGVKGEEG 351
             G  G++G  G PG KG+ G
Sbjct: 1011 RGIPGSMGNMGMPGSKGKRG 1030



 Score =  121 bits (304), Expect = 1e-27
 Identities = 81/198 (40%), Positives = 97/198 (48%), Gaps = 42/198 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGPRGLPGE--MGRPGP 252
           GP GP G  GP GP+GPPG  G  G +  G +G  G PGL G  G RG PG+  MG PG 
Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS 419

Query: 253 PG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPG 309
           PG    PG  G+PGP P  P   ++   PP     GD  L   +    + GV GP+G PG
Sbjct: 420 PGCAGSPGLPGSPGP-PGPPGDIVFRKGPP-----GDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 310 P--------PGPPGPRGPPG------------------PPGTPGSQGLAGERGTVGPSGE 343
                    PGPPG  G PG                   PG+PG+ GL G  G  G  G+
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD 533

Query: 344 PGVKGEEGEKAATAEGEG 361
           PG+KGE+GE   T + EG
Sbjct: 534 PGLKGEKGE---TLQPEG 548



 Score =  120 bits (301), Expect = 2e-27
 Identities = 82/177 (46%), Positives = 87/177 (49%), Gaps = 11/177 (6%)

Query: 190 PRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P Q+  TGP G PG  GP   PG  G  GSKG RG +G  G +G PGL G PG  G  G 
Sbjct: 60  PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 247 MGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           +G PG  G  G  G PG       P  P  A    Q        D  L  A  D  L G 
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL-DAKGDPGLPGA 178

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP--GVKGEEGEKAAT 356
           PGP+G PGPPG PGP GPPGPPG  G  G  G RG  G  GE   G KGE G K  T
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235



 Score =  117 bits (292), Expect = 3e-26
 Identities = 83/218 (38%), Positives = 93/218 (42%), Gaps = 44/218 (20%)

Query: 190 PRQRRPTGPAGPPGQ-----------TGPPGPAGPPGSKGDRGQT-------GEKGPAGP 231
           P    P GPAGPPG             G PG  GPPG  G RG+        G  GP GP
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG------PSPNSPQGALYSLQPPTDKDNG 285
           PG  GP GP G+PG +G+ G PG PGP G PG      P P  P+G      P T    G
Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF--PGTKGSLG 721

Query: 286 DSRLASAIVDTVLAGVPGPRGPP--------GPPGPPGPRGP---------PGPPGTPGS 328
                         G+PG +G P        G PG PG RG          PG PG PG+
Sbjct: 722 CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGT 781

Query: 329 QGLAGERGTVGPSGEPGVKGEEGEKAATAEG-EGVQQL 365
            G  G  G  G  G+PG  GE+G      EG  G Q L
Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819



 Score =  116 bits (290), Expect = 5e-26
 Identities = 80/200 (40%), Positives = 87/200 (43%), Gaps = 35/200 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGP------------ 240
           P GP GPPG  G PG  GP G KG  G+   G KG  G  GL GPPGP            
Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPD 252

Query: 241 -----RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYS--LQPPTDKDN-----GDSR 288
                +G  G+ G  G PGPPGP+G PG S  S +GA     LQ    KD      G   
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQGLAGERGTVG 339
           +        L G  G +G  G  GPPG RGP          G  GTPG  G  G RG  G
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 340 PSGEPGVKGEEGEKAATAEG 359
           PSG PGV G  G       G
Sbjct: 373 PSGPPGVPGSPGSSRPGLRG 392



 Score =  115 bits (287), Expect = 1e-25
 Identities = 77/210 (36%), Positives = 89/210 (42%), Gaps = 56/210 (26%)

Query: 183 IPLAHPVPRQRRPTGPAGPPGQTGPPGPAG--------------------------PPGS 216
           + ++ PVP    P GP G PG  GPPG  G                          PPG 
Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 217 KGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRP--GPPGPPGPAGNPGPSPNSPQG 271
           KGD+G  G KG  G PG +G    PG  GLPG  G P    PG PG  G PG   NS + 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 272 ALYSLQ--PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP------- 322
               L   P      G+             G+ GPRG PG PGPPG +GPPG        
Sbjct: 768 GEIGLPGLPGLPGTPGNE------------GLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 323 ----PGTPGSQGLAGERGTVGPSGEPGVKG 348
               PG  G +G  G RG  GP G+PG+ G
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score =  113 bits (282), Expect = 4e-25
 Identities = 81/201 (40%), Positives = 88/201 (43%), Gaps = 40/201 (19%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGP------------------------PGSKGDRGQTG 224
            VP      G  G PG  GPPGP G                         PGSKG RG  G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 225  EKGPAGPPGLLGPPGPRGLPGEMGRPG-----PPGPPGPAGNPG-PSPNSPQGALYSLQP 278
              G AG PGL   PG  GL G+ G PG      PGPPGP G+PG P     +G +    P
Sbjct: 1034 FPGRAGRPGL---PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 279  PTD-KDNGDSRLASAIVDTVLAGVPGP------RGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            P      G      +     L G PGP      +G  G  GPPG RGPPG PG PGS G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 332  AGERGTVGPSGEPGVKGEEGE 352
             G RG  G  G PG  GE+GE
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGE 1171



 Score =  112 bits (281), Expect = 5e-25
 Identities = 83/233 (35%), Positives = 98/233 (42%), Gaps = 69/233 (29%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPP---------GSKGDRGQTGE-----KGPAGPPGL 234
           +P    P G  GPPG  GP GP GPP         G +G +G  GE     KG  G  GL
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGL 234

Query: 235 LGPPGP-----------------RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGAL--YS 275
            GPPGP                 +G  G+ G  G PGPPGP+G PG S  S +GA     
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 276 LQPPTDKD-----------NGDSRLASAIVDTVLAGVPGPRGPP---------------- 308
           LQ    KD            G+      + +  + G  G  GPP                
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 309 --GPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             G PGPPGPR      GP GPPG PGS G +   G  G  G PG+KG +GE+
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPG-SSRPGLRGAPGWPGLKGSKGER 406



 Score =  111 bits (278), Expect = 1e-24
 Identities = 76/208 (36%), Positives = 86/208 (41%), Gaps = 44/208 (21%)

Query: 197 GPAGPPGQTGPPGPAGP--PGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  G P    P GP  P  PG +G+ G+ GE G  G PGL G PG  GL G  G PG PG
Sbjct: 739 GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798

Query: 255 PPGPAGNPGPSPNSPQGA-----LYSLQ-----------------PPTDKDNGDSRLASA 292
           PPG  G PG     P+GA     L  L+                 P  D+        S 
Sbjct: 799 PPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858

Query: 293 IV-----------DTVLAGVPGPRGPPGP---------PGPPGPRGPPGPPGTPGSQGLA 332
            +                G PG  GPPG          PG  GP GPPG PGTPG +G  
Sbjct: 859 GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP 918

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G  G  G  G PG KGE+G+K      E
Sbjct: 919 GIPGVKGQRGTPGAKGEQGDKGNPGPSE 946



 Score =  109 bits (272), Expect = 6e-24
 Identities = 85/254 (33%), Positives = 100/254 (39%), Gaps = 47/254 (18%)

Query: 151 LEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQ------ 204
           L+A   P  P    P     PP +     P   P     P    P GP G  G+      
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226

Query: 205 --------TGPPGPAGP--------------PGSKGDRGQTGEKGPAGPPGL-------- 234
                   TGPPGP G                G KGD+G  GE GP GP GL        
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286

Query: 235 ---LGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDS 287
               G PG +G PG+ G PG PG  G  GN G       +  +G    + PP  +  G +
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR--GPT 344

Query: 288 RLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ--GLAGERGTVGPSGEPG 345
                  +    G PGP GP G  GP GP GPPG PG+PGS   GL G  G  G  G  G
Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 346 VKGEEGEKAATAEG 359
            +G  G+ A    G
Sbjct: 405 ERGRPGKDAMGTPG 418



 Score =  108 bits (270), Expect = 1e-23
 Identities = 80/204 (39%), Positives = 89/204 (43%), Gaps = 46/204 (22%)

Query: 197 GPAGPPG----QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL--------GPPGPRGLP 244
           GP GPPG    + GPPG  G PG  G  G  G  GP G PGLL        GPPG  GLP
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 245 GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV------- 297
           G  G  G PG  G AG  G SP SP        P      GD  L     +T+       
Sbjct: 493 GLHGVKGIPGRQGAAGLKG-SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551

Query: 298 ------LAGVPGPRGPPGPPGPPGPR------------------GPPGPPGTPGSQGLAG 333
                 L G PG +G  G PG PG +                  GPPG PG+PGS G AG
Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG 611

Query: 334 ERGT--VGPSGEPGVKGEEGEKAA 355
             G    GP GEPG++G +G   A
Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGA 635



 Score =  107 bits (267), Expect = 2e-23
 Identities = 81/227 (35%), Positives = 97/227 (42%), Gaps = 58/227 (25%)

Query: 188 PVPRQRR-PTGPAGPPGQTGPPGPAGP-----------PGSKGDRGQTGEK--------- 226
           P PR  R P GP+GPPG  G PG + P            GSKG+RG+ G+          
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 227 -----------GPAGPPGLL----GPPGPRGLPGEMGRPGPPGPPGPAGNPG-------- 263
                      GP GPPG +    GPPG  GLPG +G PG PG  GP G PG        
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 264 -PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG----- 315
            P P    G   L+ ++    +  G + L  +       G+PG  G PG  G PG     
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQ-GAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 316 -----PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
                P G  G PG PG +G  G +G  G  G PGVKG  G K   A
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587



 Score =  107 bits (267), Expect = 2e-23
 Identities = 78/204 (38%), Positives = 92/204 (45%), Gaps = 17/204 (8%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA---------GPPG 215
            P P   P T  +   P  IP    V  QR   G  G  G  G PGP+         G PG
Sbjct: 903  PGPPGNPGTPGQRGSP-GIP---GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG 958

Query: 216  SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALY 274
             KG  G  GEKG  G PG+ G  G +GLPG  G PGP G  G  GNPG P      G++ 
Sbjct: 959  LKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMG 1018

Query: 275  SLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPG-PPGPR-GPPGPPGTPGSQGL 331
            ++  P  K   G            L G+ G +G  G PG   G R GPPGP G PG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 332  AGERGTVGPSGEPGVKGEEGEKAA 355
             G++G +G  G PG  G  G + A
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGA 1102



 Score =  104 bits (259), Expect = 2e-22
 Identities = 65/172 (37%), Positives = 72/172 (41%), Gaps = 22/172 (12%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP------------------P 238
           G  G PG  G  G  G PG  G+ G  G+KG  GPPG  GP                  P
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           GPRG  G  G  GPPG PG  G+  P      G         ++                
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 299 AGVPGPRGPPGPPGPPGP----RGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
           AG PG  G PGPPGPPG     +GPPG  G PG  G  G  G  GP GEPG+
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 70/186 (37%), Positives = 80/186 (43%), Gaps = 33/186 (17%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP GPPG  G PG  G PG  G +GQ G  G  G  G  G PGP  +   +G  G PG  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 257  GPAGNPGPS-----PNSPQ-GALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            G AGNPG       P  P    L  L  P         L S    T   G PG RG PG 
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS----TGNPGEPGLRGIPGS 1016

Query: 311  ------PGPPGPRGP------PGPPGTPGSQGLAGER-----------GTVGPSGEPGVK 347
                  PG  G RG        G PG PG  GL G++           G  GP+G+PG+ 
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 348  GEEGEK 353
            G+ G+K
Sbjct: 1077 GDMGKK 1082



 Score = 93.6 bits (231), Expect = 3e-19
 Identities = 46/91 (50%), Positives = 52/91 (57%), Gaps = 10/91 (10%)

Query: 195  PTGPAGPPGQTGPPGPA---------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
            P GP GPPG  G PG           GPPG+ G+ G  GE GP GPPG LGP GPRG PG
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 246  EMGRPGPPGPPGPAGNPGPSPNSPQGALYSL 276
            + G+PG PGP G  GN G S   P+   + L
Sbjct: 1395 KDGKPGTPGPAGEKGNKG-SKGEPESLFHQL 1424



 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 62/167 (37%), Positives = 74/167 (44%), Gaps = 37/167 (22%)

Query: 211 AGPPGSKG----DRGQT---GEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
           A P  SKG    D+GQ    G KG  G  G  GPPG  G  G  G  G PGP GP G PG
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 264 -PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGP--- 319
            P     +G                          ++G+PG  G PG PG PG  GP   
Sbjct: 83  LPGLTGSKGV-----------------------RGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 320 ---PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
              PG  G+ G QG  G  GT+G  G PG  G +G+K A A+ E ++
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166



 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 64/201 (31%), Positives = 70/201 (34%), Gaps = 71/201 (35%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPR-------QRRPTGPAGPPGQTGPPGPAGPPGSK 217
            P P   P +       D   + HP P+          P G  G PG  G PGP G PG +
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 218  GDRGQTGEKG---------------PAGPPGLLG---------------PPGPRGLPGEM 247
            G  G  GEKG               P GPPG+ G               PPG  G PG  
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQ 1372

Query: 248  GRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGP 307
            G PGPPGPPG  G  GP                                   G PG  G 
Sbjct: 1373 GEPGPPGPPGNLGPCGP----------------------------------RGKPGKDGK 1398

Query: 308  PGPPGPPGPRGPPGPPGTPGS 328
            PG PGP G +G  G  G P S
Sbjct: 1399 PGTPGPAGEKGNKGSKGEPES 1419


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  142 bits (358), Expect = 6e-34
 Identities = 86/200 (43%), Positives = 97/200 (48%), Gaps = 26/200 (13%)

Query: 172  PTWNEDF-----LPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS-----KGDRG 221
            PT  E F     LP AI     +P Q    GP G  G  G PGP GPPGS     KGD+G
Sbjct: 1217 PTGIEGFPGPPGLPGAI-----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG 1271

Query: 222  QTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-------PSPNSPQGALY 274
              G  GP GPPG  G  GP   PG +G PG PG PGP G+PG              G L 
Sbjct: 1272 SMGHPGPKGPPGTAGDMGP---PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 275  SLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAG 333
            S+ PP      G   +        +  +PG  GPPG PG PG +G PGPPG PG+ G  G
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 334  ERGTVGPSGEPGVKGEEGEK 353
             RG  G  G+PG  G  GEK
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEK 1408



 Score =  132 bits (333), Expect = 5e-31
 Identities = 78/174 (44%), Positives = 89/174 (51%), Gaps = 29/174 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR----P 250
           P G  G PG  GP GPAGPPG  G +G+ G +G  G PG  GPPG  G  GE+      P
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGPPGP G+PGP    P G   SL    D                  G+PGP G PG 
Sbjct: 656 GPPGPPGPPGHPGPQ--GPPGIPGSLGKCGDP-----------------GLPGPDGEPGI 696

Query: 311 PG-----PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           PG     PPGP+G  G PGT GS G  G+ G  G  G+PG+ G +GE A    G
Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG 750



 Score =  127 bits (318), Expect = 3e-29
 Identities = 91/232 (39%), Positives = 101/232 (43%), Gaps = 70/232 (30%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P    P GP G PG  G PG  G PG  GD G  G KG  GPPG+ GP         PGP
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 241  RGLPGEMGRPGPPG-------------PPGPAGNPGP--------SPNSP-----QGALY 274
             G+ G+ GR G PG             PPGP GNPG         +P  P     +GA+ 
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 275  SLQP--PTDKDN--GDSRLASAIV--DTVLAGVPGPRGPPGPPGPPGP------------ 316
               P  PT  +   G   L  AI+   T   G PG RG PG PGPPGP            
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 317  -----RGPPGPPGT------------PGSQGLAGERGTVGPSGEPGVKGEEG 351
                  GP GPPGT            PG+ GL G RG  G  G PGVKGE+G
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322



 Score =  126 bits (316), Expect = 4e-29
 Identities = 81/189 (42%), Positives = 87/189 (46%), Gaps = 38/189 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG----PAGPPGLLGPPGPRGLPGEMGRPGP 252
           G  G PG TG PG  G PG++GD G  GEKG    P G  G+ G PG RG PG  G  G 
Sbjct: 511 GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 253 PGPPGPAGNPGP--------------------SPNSPQGALYSLQPPTDKDNGDSRLASA 292
           PG PG  G PGP                    SP SP G      PP     G+  L   
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAGPPGYGPQGEPGLQGT 629

Query: 293 IVDTVLAGVPG---PRG----------PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  G PG   PRG          PPGPPGPPG  GP GPPG PGS G  G+ G  G
Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 340 PSGEPGVKG 348
           P GEPG+ G
Sbjct: 690 PDGEPGIPG 698



 Score =  124 bits (311), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 84/187 (44%), Gaps = 23/187 (12%)

Query: 197  GPAGPPGQT-----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            G  G PG +     GPPGP G PG  GD G+ GE G  GPPG LGP GP G PG  G PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 252  PPGPPGPAGNPG----------PSPNSPQG--------ALYSLQPPTDKDNGDSRLASAI 293
             PG PGP G+ G          P    P G            ++    +D          
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 294  VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
               +L   PGPRG PG  G  G RG PG PG PG +G  G+ G  GP+G  G  G  G  
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 354  AATAEGE 360
             A   G+
Sbjct: 1231 GAIIPGQ 1237



 Score =  122 bits (306), Expect = 6e-28
 Identities = 77/200 (38%), Positives = 96/200 (48%), Gaps = 40/200 (20%)

Query: 192  QRRPTGPAGPPG-----QTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            +R  TGP G PG     ++G PG  G PG    +G+ G  G++G  G PG+LGPPG  G+
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890

Query: 244  PGEMGRPGPPGPPGPAGNPG----------PSPNSPQGALYSLQPPTDKDN-GDSRLASA 292
             G MG PG  GPPGP GNPG          P     +G   +     DK N G S ++  
Sbjct: 891  IGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHV 950

Query: 293  IVD---------------------TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            I D                       + G+ G +G PGP GPPGPRG  G  G PG  GL
Sbjct: 951  IGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL 1010

Query: 332  AGERGTVGPSGEPGVKGEEG 351
             G  G++G  G PG KG+ G
Sbjct: 1011 RGIPGSMGNMGMPGSKGKRG 1030



 Score =  121 bits (304), Expect = 1e-27
 Identities = 81/198 (40%), Positives = 97/198 (48%), Gaps = 42/198 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGPRGLPGE--MGRPGP 252
           GP GP G  GP GP+GPPG  G  G +  G +G  G PGL G  G RG PG+  MG PG 
Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS 419

Query: 253 PG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPG 309
           PG    PG  G+PGP P  P   ++   PP     GD  L   +    + GV GP+G PG
Sbjct: 420 PGCAGSPGLPGSPGP-PGPPGDIVFRKGPP-----GDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 310 P--------PGPPGPRGPPG------------------PPGTPGSQGLAGERGTVGPSGE 343
                    PGPPG  G PG                   PG+PG+ GL G  G  G  G+
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD 533

Query: 344 PGVKGEEGEKAATAEGEG 361
           PG+KGE+GE   T + EG
Sbjct: 534 PGLKGEKGE---TLQPEG 548



 Score =  120 bits (301), Expect = 2e-27
 Identities = 82/177 (46%), Positives = 87/177 (49%), Gaps = 11/177 (6%)

Query: 190 PRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P Q+  TGP G PG  GP   PG  G  GSKG RG +G  G +G PGL G PG  G  G 
Sbjct: 60  PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 247 MGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           +G PG  G  G  G PG       P  P  A    Q        D  L  A  D  L G 
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL-DAKGDPGLPGA 178

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP--GVKGEEGEKAAT 356
           PGP+G PGPPG PGP GPPGPPG  G  G  G RG  G  GE   G KGE G K  T
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235



 Score =  117 bits (292), Expect = 3e-26
 Identities = 83/218 (38%), Positives = 93/218 (42%), Gaps = 44/218 (20%)

Query: 190 PRQRRPTGPAGPPGQ-----------TGPPGPAGPPGSKGDRGQT-------GEKGPAGP 231
           P    P GPAGPPG             G PG  GPPG  G RG+        G  GP GP
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG------PSPNSPQGALYSLQPPTDKDNG 285
           PG  GP GP G+PG +G+ G PG PGP G PG      P P  P+G      P T    G
Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF--PGTKGSLG 721

Query: 286 DSRLASAIVDTVLAGVPGPRGPP--------GPPGPPGPRGP---------PGPPGTPGS 328
                         G+PG +G P        G PG PG RG          PG PG PG+
Sbjct: 722 CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGT 781

Query: 329 QGLAGERGTVGPSGEPGVKGEEGEKAATAEG-EGVQQL 365
            G  G  G  G  G+PG  GE+G      EG  G Q L
Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819



 Score =  116 bits (290), Expect = 5e-26
 Identities = 80/200 (40%), Positives = 87/200 (43%), Gaps = 35/200 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGP------------ 240
           P GP GPPG  G PG  GP G KG  G+   G KG  G  GL GPPGP            
Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPD 252

Query: 241 -----RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYS--LQPPTDKDN-----GDSR 288
                +G  G+ G  G PGPPGP+G PG S  S +GA     LQ    KD      G   
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQGLAGERGTVG 339
           +        L G  G +G  G  GPPG RGP          G  GTPG  G  G RG  G
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 340 PSGEPGVKGEEGEKAATAEG 359
           PSG PGV G  G       G
Sbjct: 373 PSGPPGVPGSPGSSRPGLRG 392



 Score =  115 bits (287), Expect = 1e-25
 Identities = 77/210 (36%), Positives = 89/210 (42%), Gaps = 56/210 (26%)

Query: 183 IPLAHPVPRQRRPTGPAGPPGQTGPPGPAG--------------------------PPGS 216
           + ++ PVP    P GP G PG  GPPG  G                          PPG 
Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 217 KGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRP--GPPGPPGPAGNPGPSPNSPQG 271
           KGD+G  G KG  G PG +G    PG  GLPG  G P    PG PG  G PG   NS + 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 272 ALYSLQ--PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP------- 322
               L   P      G+             G+ GPRG PG PGPPG +GPPG        
Sbjct: 768 GEIGLPGLPGLPGTPGNE------------GLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 323 ----PGTPGSQGLAGERGTVGPSGEPGVKG 348
               PG  G +G  G RG  GP G+PG+ G
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score =  113 bits (282), Expect = 4e-25
 Identities = 81/201 (40%), Positives = 88/201 (43%), Gaps = 40/201 (19%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGP------------------------PGSKGDRGQTG 224
            VP      G  G PG  GPPGP G                         PGSKG RG  G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 225  EKGPAGPPGLLGPPGPRGLPGEMGRPG-----PPGPPGPAGNPG-PSPNSPQGALYSLQP 278
              G AG PGL   PG  GL G+ G PG      PGPPGP G+PG P     +G +    P
Sbjct: 1034 FPGRAGRPGL---PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 279  PTD-KDNGDSRLASAIVDTVLAGVPGP------RGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            P      G      +     L G PGP      +G  G  GPPG RGPPG PG PGS G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 332  AGERGTVGPSGEPGVKGEEGE 352
             G RG  G  G PG  GE+GE
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGE 1171



 Score =  112 bits (281), Expect = 5e-25
 Identities = 83/233 (35%), Positives = 98/233 (42%), Gaps = 69/233 (29%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPP---------GSKGDRGQTGE-----KGPAGPPGL 234
           +P    P G  GPPG  GP GP GPP         G +G +G  GE     KG  G  GL
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGL 234

Query: 235 LGPPGP-----------------RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGAL--YS 275
            GPPGP                 +G  G+ G  G PGPPGP+G PG S  S +GA     
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 276 LQPPTDKD-----------NGDSRLASAIVDTVLAGVPGPRGPP---------------- 308
           LQ    KD            G+      + +  + G  G  GPP                
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 309 --GPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             G PGPPGPR      GP GPPG PGS G +   G  G  G PG+KG +GE+
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPG-SSRPGLRGAPGWPGLKGSKGER 406



 Score =  111 bits (278), Expect = 1e-24
 Identities = 76/208 (36%), Positives = 86/208 (41%), Gaps = 44/208 (21%)

Query: 197 GPAGPPGQTGPPGPAGP--PGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  G P    P GP  P  PG +G+ G+ GE G  G PGL G PG  GL G  G PG PG
Sbjct: 739 GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798

Query: 255 PPGPAGNPGPSPNSPQGA-----LYSLQ-----------------PPTDKDNGDSRLASA 292
           PPG  G PG     P+GA     L  L+                 P  D+        S 
Sbjct: 799 PPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858

Query: 293 IV-----------DTVLAGVPGPRGPPGP---------PGPPGPRGPPGPPGTPGSQGLA 332
            +                G PG  GPPG          PG  GP GPPG PGTPG +G  
Sbjct: 859 GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP 918

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G  G  G  G PG KGE+G+K      E
Sbjct: 919 GIPGVKGQRGTPGAKGEQGDKGNPGPSE 946



 Score =  109 bits (272), Expect = 6e-24
 Identities = 85/254 (33%), Positives = 100/254 (39%), Gaps = 47/254 (18%)

Query: 151 LEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQ------ 204
           L+A   P  P    P     PP +     P   P     P    P GP G  G+      
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226

Query: 205 --------TGPPGPAGP--------------PGSKGDRGQTGEKGPAGPPGL-------- 234
                   TGPPGP G                G KGD+G  GE GP GP GL        
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286

Query: 235 ---LGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDS 287
               G PG +G PG+ G PG PG  G  GN G       +  +G    + PP  +  G +
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR--GPT 344

Query: 288 RLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ--GLAGERGTVGPSGEPG 345
                  +    G PGP GP G  GP GP GPPG PG+PGS   GL G  G  G  G  G
Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 346 VKGEEGEKAATAEG 359
            +G  G+ A    G
Sbjct: 405 ERGRPGKDAMGTPG 418



 Score =  108 bits (270), Expect = 1e-23
 Identities = 80/204 (39%), Positives = 89/204 (43%), Gaps = 46/204 (22%)

Query: 197 GPAGPPG----QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL--------GPPGPRGLP 244
           GP GPPG    + GPPG  G PG  G  G  G  GP G PGLL        GPPG  GLP
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 245 GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV------- 297
           G  G  G PG  G AG  G SP SP        P      GD  L     +T+       
Sbjct: 493 GLHGVKGIPGRQGAAGLKG-SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551

Query: 298 ------LAGVPGPRGPPGPPGPPGPR------------------GPPGPPGTPGSQGLAG 333
                 L G PG +G  G PG PG +                  GPPG PG+PGS G AG
Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG 611

Query: 334 ERGT--VGPSGEPGVKGEEGEKAA 355
             G    GP GEPG++G +G   A
Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGA 635



 Score =  107 bits (267), Expect = 2e-23
 Identities = 81/227 (35%), Positives = 97/227 (42%), Gaps = 58/227 (25%)

Query: 188 PVPRQRR-PTGPAGPPGQTGPPGPAGP-----------PGSKGDRGQTGEK--------- 226
           P PR  R P GP+GPPG  G PG + P            GSKG+RG+ G+          
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 227 -----------GPAGPPGLL----GPPGPRGLPGEMGRPGPPGPPGPAGNPG-------- 263
                      GP GPPG +    GPPG  GLPG +G PG PG  GP G PG        
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 264 -PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG----- 315
            P P    G   L+ ++    +  G + L  +       G+PG  G PG  G PG     
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQ-GAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 316 -----PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
                P G  G PG PG +G  G +G  G  G PGVKG  G K   A
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587



 Score =  107 bits (267), Expect = 2e-23
 Identities = 78/204 (38%), Positives = 92/204 (45%), Gaps = 17/204 (8%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA---------GPPG 215
            P P   P T  +   P  IP    V  QR   G  G  G  G PGP+         G PG
Sbjct: 903  PGPPGNPGTPGQRGSP-GIP---GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG 958

Query: 216  SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALY 274
             KG  G  GEKG  G PG+ G  G +GLPG  G PGP G  G  GNPG P      G++ 
Sbjct: 959  LKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMG 1018

Query: 275  SLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPG-PPGPR-GPPGPPGTPGSQGL 331
            ++  P  K   G            L G+ G +G  G PG   G R GPPGP G PG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 332  AGERGTVGPSGEPGVKGEEGEKAA 355
             G++G +G  G PG  G  G + A
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGA 1102



 Score =  104 bits (259), Expect = 2e-22
 Identities = 65/172 (37%), Positives = 72/172 (41%), Gaps = 22/172 (12%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP------------------P 238
           G  G PG  G  G  G PG  G+ G  G+KG  GPPG  GP                  P
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           GPRG  G  G  GPPG PG  G+  P      G         ++                
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 299 AGVPGPRGPPGPPGPPGP----RGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
           AG PG  G PGPPGPPG     +GPPG  G PG  G  G  G  GP GEPG+
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474



 Score =  102 bits (254), Expect = 7e-22
 Identities = 72/199 (36%), Positives = 83/199 (41%), Gaps = 37/199 (18%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPR-------QRRPTGPAGPPGQTGPPGPAGPPGSK 217
            P P   P +       D   + HP P+          P G  G PG  G PGP G PG +
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 218  GDRGQTGEKG------PAGPPGLLGPPGPRGLPGEMGR------PGPPGPPGPAGNPG-- 263
            G  G  GEKG        GPPG +GP GP G+ G+ G       PG PGPPG  G PG  
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQ 1372

Query: 264  --PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP---RGPPGPPGPPGPRG 318
              P P  P G L    P   K   D +           G PGP   +G  G  G PGP G
Sbjct: 1373 GEPGPPGPPGNLGPCGP-RGKPGKDGK----------PGTPGPAGEKGNKGSKGEPGPAG 1421

Query: 319  PPGPPGTPGSQGLAGERGT 337
              G PG  G +G +G   T
Sbjct: 1422 SDGLPGLKGKRGDSGSPAT 1440



 Score =  102 bits (253), Expect = 9e-22
 Identities = 59/150 (39%), Positives = 65/150 (43%), Gaps = 43/150 (28%)

Query: 195  PTGPAGPPGQTGPPGPA---------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
            P GP GPPG  G PG           GPPG+ G+ G  GE GP GPPG LGP GPRG PG
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 246  EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            + G+PG PGP G  GN G                                    G PGP 
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSK----------------------------------GEPGPA 1420

Query: 306  GPPGPPGPPGPRGPPGPPGTPGSQGLAGER 335
            G  G PG  G RG  G P T  ++G    R
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 70/186 (37%), Positives = 80/186 (43%), Gaps = 33/186 (17%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP GPPG  G PG  G PG  G +GQ G  G  G  G  G PGP  +   +G  G PG  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 257  GPAGNPGPS-----PNSPQ-GALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            G AGNPG       P  P    L  L  P         L S    T   G PG RG PG 
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS----TGNPGEPGLRGIPGS 1016

Query: 311  ------PGPPGPRGP------PGPPGTPGSQGLAGER-----------GTVGPSGEPGVK 347
                  PG  G RG        G PG PG  GL G++           G  GP+G+PG+ 
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 348  GEEGEK 353
            G+ G+K
Sbjct: 1077 GDMGKK 1082



 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 62/167 (37%), Positives = 74/167 (44%), Gaps = 37/167 (22%)

Query: 211 AGPPGSKG----DRGQT---GEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
           A P  SKG    D+GQ    G KG  G  G  GPPG  G  G  G  G PGP GP G PG
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 264 -PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGP--- 319
            P     +G                          ++G+PG  G PG PG PG  GP   
Sbjct: 83  LPGLTGSKGV-----------------------RGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 320 ---PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
              PG  G+ G QG  G  GT+G  G PG  G +G+K A A+ E ++
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  142 bits (358), Expect = 6e-34
 Identities = 86/200 (43%), Positives = 97/200 (48%), Gaps = 26/200 (13%)

Query: 172  PTWNEDF-----LPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS-----KGDRG 221
            PT  E F     LP AI     +P Q    GP G  G  G PGP GPPGS     KGD+G
Sbjct: 1217 PTGIEGFPGPPGLPGAI-----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG 1271

Query: 222  QTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-------PSPNSPQGALY 274
              G  GP GPPG  G  GP   PG +G PG PG PGP G+PG              G L 
Sbjct: 1272 SMGHPGPKGPPGTAGDMGP---PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 275  SLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAG 333
            S+ PP      G   +        +  +PG  GPPG PG PG +G PGPPG PG+ G  G
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 334  ERGTVGPSGEPGVKGEEGEK 353
             RG  G  G+PG  G  GEK
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEK 1408



 Score =  132 bits (333), Expect = 5e-31
 Identities = 78/174 (44%), Positives = 89/174 (51%), Gaps = 29/174 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR----P 250
           P G  G PG  GP GPAGPPG  G +G+ G +G  G PG  GPPG  G  GE+      P
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGPPGP G+PGP    P G   SL    D                  G+PGP G PG 
Sbjct: 656 GPPGPPGPPGHPGPQ--GPPGIPGSLGKCGDP-----------------GLPGPDGEPGI 696

Query: 311 PG-----PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           PG     PPGP+G  G PGT GS G  G+ G  G  G+PG+ G +GE A    G
Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG 750



 Score =  127 bits (318), Expect = 3e-29
 Identities = 91/232 (39%), Positives = 101/232 (43%), Gaps = 70/232 (30%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P    P GP G PG  G PG  G PG  GD G  G KG  GPPG+ GP         PGP
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 241  RGLPGEMGRPGPPG-------------PPGPAGNPGP--------SPNSP-----QGALY 274
             G+ G+ GR G PG             PPGP GNPG         +P  P     +GA+ 
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 275  SLQP--PTDKDN--GDSRLASAIV--DTVLAGVPGPRGPPGPPGPPGP------------ 316
               P  PT  +   G   L  AI+   T   G PG RG PG PGPPGP            
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 317  -----RGPPGPPGT------------PGSQGLAGERGTVGPSGEPGVKGEEG 351
                  GP GPPGT            PG+ GL G RG  G  G PGVKGE+G
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322



 Score =  126 bits (316), Expect = 4e-29
 Identities = 81/189 (42%), Positives = 87/189 (46%), Gaps = 38/189 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG----PAGPPGLLGPPGPRGLPGEMGRPGP 252
           G  G PG TG PG  G PG++GD G  GEKG    P G  G+ G PG RG PG  G  G 
Sbjct: 511 GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 253 PGPPGPAGNPGP--------------------SPNSPQGALYSLQPPTDKDNGDSRLASA 292
           PG PG  G PGP                    SP SP G      PP     G+  L   
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAGPPGYGPQGEPGLQGT 629

Query: 293 IVDTVLAGVPG---PRG----------PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  G PG   PRG          PPGPPGPPG  GP GPPG PGS G  G+ G  G
Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 340 PSGEPGVKG 348
           P GEPG+ G
Sbjct: 690 PDGEPGIPG 698



 Score =  124 bits (311), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 84/187 (44%), Gaps = 23/187 (12%)

Query: 197  GPAGPPGQT-----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            G  G PG +     GPPGP G PG  GD G+ GE G  GPPG LGP GP G PG  G PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 252  PPGPPGPAGNPG----------PSPNSPQG--------ALYSLQPPTDKDNGDSRLASAI 293
             PG PGP G+ G          P    P G            ++    +D          
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 294  VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
               +L   PGPRG PG  G  G RG PG PG PG +G  G+ G  GP+G  G  G  G  
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 354  AATAEGE 360
             A   G+
Sbjct: 1231 GAIIPGQ 1237



 Score =  122 bits (306), Expect = 6e-28
 Identities = 77/200 (38%), Positives = 96/200 (48%), Gaps = 40/200 (20%)

Query: 192  QRRPTGPAGPPG-----QTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            +R  TGP G PG     ++G PG  G PG    +G+ G  G++G  G PG+LGPPG  G+
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890

Query: 244  PGEMGRPGPPGPPGPAGNPG----------PSPNSPQGALYSLQPPTDKDN-GDSRLASA 292
             G MG PG  GPPGP GNPG          P     +G   +     DK N G S ++  
Sbjct: 891  IGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHV 950

Query: 293  IVD---------------------TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            I D                       + G+ G +G PGP GPPGPRG  G  G PG  GL
Sbjct: 951  IGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL 1010

Query: 332  AGERGTVGPSGEPGVKGEEG 351
             G  G++G  G PG KG+ G
Sbjct: 1011 RGIPGSMGNMGMPGSKGKRG 1030



 Score =  121 bits (304), Expect = 1e-27
 Identities = 81/198 (40%), Positives = 97/198 (48%), Gaps = 42/198 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGPRGLPGE--MGRPGP 252
           GP GP G  GP GP+GPPG  G  G +  G +G  G PGL G  G RG PG+  MG PG 
Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS 419

Query: 253 PG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPG 309
           PG    PG  G+PGP P  P   ++   PP     GD  L   +    + GV GP+G PG
Sbjct: 420 PGCAGSPGLPGSPGP-PGPPGDIVFRKGPP-----GDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 310 P--------PGPPGPRGPPG------------------PPGTPGSQGLAGERGTVGPSGE 343
                    PGPPG  G PG                   PG+PG+ GL G  G  G  G+
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD 533

Query: 344 PGVKGEEGEKAATAEGEG 361
           PG+KGE+GE   T + EG
Sbjct: 534 PGLKGEKGE---TLQPEG 548



 Score =  120 bits (301), Expect = 2e-27
 Identities = 82/177 (46%), Positives = 87/177 (49%), Gaps = 11/177 (6%)

Query: 190 PRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P Q+  TGP G PG  GP   PG  G  GSKG RG +G  G +G PGL G PG  G  G 
Sbjct: 60  PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 247 MGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           +G PG  G  G  G PG       P  P  A    Q        D  L  A  D  L G 
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL-DAKGDPGLPGA 178

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP--GVKGEEGEKAAT 356
           PGP+G PGPPG PGP GPPGPPG  G  G  G RG  G  GE   G KGE G K  T
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235



 Score =  117 bits (292), Expect = 3e-26
 Identities = 83/218 (38%), Positives = 93/218 (42%), Gaps = 44/218 (20%)

Query: 190 PRQRRPTGPAGPPGQ-----------TGPPGPAGPPGSKGDRGQT-------GEKGPAGP 231
           P    P GPAGPPG             G PG  GPPG  G RG+        G  GP GP
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG------PSPNSPQGALYSLQPPTDKDNG 285
           PG  GP GP G+PG +G+ G PG PGP G PG      P P  P+G      P T    G
Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF--PGTKGSLG 721

Query: 286 DSRLASAIVDTVLAGVPGPRGPP--------GPPGPPGPRGP---------PGPPGTPGS 328
                         G+PG +G P        G PG PG RG          PG PG PG+
Sbjct: 722 CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGT 781

Query: 329 QGLAGERGTVGPSGEPGVKGEEGEKAATAEG-EGVQQL 365
            G  G  G  G  G+PG  GE+G      EG  G Q L
Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819



 Score =  116 bits (290), Expect = 5e-26
 Identities = 80/200 (40%), Positives = 87/200 (43%), Gaps = 35/200 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGP------------ 240
           P GP GPPG  G PG  GP G KG  G+   G KG  G  GL GPPGP            
Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPD 252

Query: 241 -----RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYS--LQPPTDKDN-----GDSR 288
                +G  G+ G  G PGPPGP+G PG S  S +GA     LQ    KD      G   
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQGLAGERGTVG 339
           +        L G  G +G  G  GPPG RGP          G  GTPG  G  G RG  G
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 340 PSGEPGVKGEEGEKAATAEG 359
           PSG PGV G  G       G
Sbjct: 373 PSGPPGVPGSPGSSRPGLRG 392



 Score =  115 bits (287), Expect = 1e-25
 Identities = 77/210 (36%), Positives = 89/210 (42%), Gaps = 56/210 (26%)

Query: 183 IPLAHPVPRQRRPTGPAGPPGQTGPPGPAG--------------------------PPGS 216
           + ++ PVP    P GP G PG  GPPG  G                          PPG 
Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 217 KGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRP--GPPGPPGPAGNPGPSPNSPQG 271
           KGD+G  G KG  G PG +G    PG  GLPG  G P    PG PG  G PG   NS + 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 272 ALYSLQ--PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP------- 322
               L   P      G+             G+ GPRG PG PGPPG +GPPG        
Sbjct: 768 GEIGLPGLPGLPGTPGNE------------GLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 323 ----PGTPGSQGLAGERGTVGPSGEPGVKG 348
               PG  G +G  G RG  GP G+PG+ G
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score =  113 bits (282), Expect = 4e-25
 Identities = 81/201 (40%), Positives = 88/201 (43%), Gaps = 40/201 (19%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGP------------------------PGSKGDRGQTG 224
            VP      G  G PG  GPPGP G                         PGSKG RG  G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 225  EKGPAGPPGLLGPPGPRGLPGEMGRPG-----PPGPPGPAGNPG-PSPNSPQGALYSLQP 278
              G AG PGL   PG  GL G+ G PG      PGPPGP G+PG P     +G +    P
Sbjct: 1034 FPGRAGRPGL---PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 279  PTD-KDNGDSRLASAIVDTVLAGVPGP------RGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            P      G      +     L G PGP      +G  G  GPPG RGPPG PG PGS G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 332  AGERGTVGPSGEPGVKGEEGE 352
             G RG  G  G PG  GE+GE
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGE 1171



 Score =  112 bits (281), Expect = 5e-25
 Identities = 83/233 (35%), Positives = 98/233 (42%), Gaps = 69/233 (29%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPP---------GSKGDRGQTGE-----KGPAGPPGL 234
           +P    P G  GPPG  GP GP GPP         G +G +G  GE     KG  G  GL
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGL 234

Query: 235 LGPPGP-----------------RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGAL--YS 275
            GPPGP                 +G  G+ G  G PGPPGP+G PG S  S +GA     
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 276 LQPPTDKD-----------NGDSRLASAIVDTVLAGVPGPRGPP---------------- 308
           LQ    KD            G+      + +  + G  G  GPP                
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 309 --GPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             G PGPPGPR      GP GPPG PGS G +   G  G  G PG+KG +GE+
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPG-SSRPGLRGAPGWPGLKGSKGER 406



 Score =  111 bits (278), Expect = 1e-24
 Identities = 76/208 (36%), Positives = 86/208 (41%), Gaps = 44/208 (21%)

Query: 197 GPAGPPGQTGPPGPAGP--PGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  G P    P GP  P  PG +G+ G+ GE G  G PGL G PG  GL G  G PG PG
Sbjct: 739 GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798

Query: 255 PPGPAGNPGPSPNSPQGA-----LYSLQ-----------------PPTDKDNGDSRLASA 292
           PPG  G PG     P+GA     L  L+                 P  D+        S 
Sbjct: 799 PPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858

Query: 293 IV-----------DTVLAGVPGPRGPPGP---------PGPPGPRGPPGPPGTPGSQGLA 332
            +                G PG  GPPG          PG  GP GPPG PGTPG +G  
Sbjct: 859 GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP 918

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G  G  G  G PG KGE+G+K      E
Sbjct: 919 GIPGVKGQRGTPGAKGEQGDKGNPGPSE 946



 Score =  109 bits (272), Expect = 6e-24
 Identities = 85/254 (33%), Positives = 100/254 (39%), Gaps = 47/254 (18%)

Query: 151 LEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQ------ 204
           L+A   P  P    P     PP +     P   P     P    P GP G  G+      
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226

Query: 205 --------TGPPGPAGP--------------PGSKGDRGQTGEKGPAGPPGL-------- 234
                   TGPPGP G                G KGD+G  GE GP GP GL        
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286

Query: 235 ---LGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDS 287
               G PG +G PG+ G PG PG  G  GN G       +  +G    + PP  +  G +
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR--GPT 344

Query: 288 RLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ--GLAGERGTVGPSGEPG 345
                  +    G PGP GP G  GP GP GPPG PG+PGS   GL G  G  G  G  G
Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 346 VKGEEGEKAATAEG 359
            +G  G+ A    G
Sbjct: 405 ERGRPGKDAMGTPG 418



 Score =  108 bits (270), Expect = 1e-23
 Identities = 80/204 (39%), Positives = 89/204 (43%), Gaps = 46/204 (22%)

Query: 197 GPAGPPG----QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL--------GPPGPRGLP 244
           GP GPPG    + GPPG  G PG  G  G  G  GP G PGLL        GPPG  GLP
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 245 GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV------- 297
           G  G  G PG  G AG  G SP SP        P      GD  L     +T+       
Sbjct: 493 GLHGVKGIPGRQGAAGLKG-SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551

Query: 298 ------LAGVPGPRGPPGPPGPPGPR------------------GPPGPPGTPGSQGLAG 333
                 L G PG +G  G PG PG +                  GPPG PG+PGS G AG
Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG 611

Query: 334 ERGT--VGPSGEPGVKGEEGEKAA 355
             G    GP GEPG++G +G   A
Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGA 635



 Score =  107 bits (267), Expect = 2e-23
 Identities = 81/227 (35%), Positives = 97/227 (42%), Gaps = 58/227 (25%)

Query: 188 PVPRQRR-PTGPAGPPGQTGPPGPAGP-----------PGSKGDRGQTGEK--------- 226
           P PR  R P GP+GPPG  G PG + P            GSKG+RG+ G+          
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 227 -----------GPAGPPGLL----GPPGPRGLPGEMGRPGPPGPPGPAGNPG-------- 263
                      GP GPPG +    GPPG  GLPG +G PG PG  GP G PG        
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 264 -PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG----- 315
            P P    G   L+ ++    +  G + L  +       G+PG  G PG  G PG     
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQ-GAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 316 -----PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
                P G  G PG PG +G  G +G  G  G PGVKG  G K   A
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587



 Score =  107 bits (267), Expect = 2e-23
 Identities = 78/204 (38%), Positives = 92/204 (45%), Gaps = 17/204 (8%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA---------GPPG 215
            P P   P T  +   P  IP    V  QR   G  G  G  G PGP+         G PG
Sbjct: 903  PGPPGNPGTPGQRGSP-GIP---GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG 958

Query: 216  SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALY 274
             KG  G  GEKG  G PG+ G  G +GLPG  G PGP G  G  GNPG P      G++ 
Sbjct: 959  LKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMG 1018

Query: 275  SLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPG-PPGPR-GPPGPPGTPGSQGL 331
            ++  P  K   G            L G+ G +G  G PG   G R GPPGP G PG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 332  AGERGTVGPSGEPGVKGEEGEKAA 355
             G++G +G  G PG  G  G + A
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGA 1102



 Score =  104 bits (259), Expect = 2e-22
 Identities = 65/172 (37%), Positives = 72/172 (41%), Gaps = 22/172 (12%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP------------------P 238
           G  G PG  G  G  G PG  G+ G  G+KG  GPPG  GP                  P
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           GPRG  G  G  GPPG PG  G+  P      G         ++                
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 299 AGVPGPRGPPGPPGPPGP----RGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
           AG PG  G PGPPGPPG     +GPPG  G PG  G  G  G  GP GEPG+
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474



 Score =  102 bits (254), Expect = 7e-22
 Identities = 72/199 (36%), Positives = 83/199 (41%), Gaps = 37/199 (18%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPR-------QRRPTGPAGPPGQTGPPGPAGPPGSK 217
            P P   P +       D   + HP P+          P G  G PG  G PGP G PG +
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 218  GDRGQTGEKG------PAGPPGLLGPPGPRGLPGEMGR------PGPPGPPGPAGNPG-- 263
            G  G  GEKG        GPPG +GP GP G+ G+ G       PG PGPPG  G PG  
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQ 1372

Query: 264  --PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP---RGPPGPPGPPGPRG 318
              P P  P G L    P   K   D +           G PGP   +G  G  G PGP G
Sbjct: 1373 GEPGPPGPPGNLGPCGP-RGKPGKDGK----------PGTPGPAGEKGNKGSKGEPGPAG 1421

Query: 319  PPGPPGTPGSQGLAGERGT 337
              G PG  G +G +G   T
Sbjct: 1422 SDGLPGLKGKRGDSGSPAT 1440



 Score =  102 bits (253), Expect = 9e-22
 Identities = 59/150 (39%), Positives = 65/150 (43%), Gaps = 43/150 (28%)

Query: 195  PTGPAGPPGQTGPPGPA---------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
            P GP GPPG  G PG           GPPG+ G+ G  GE GP GPPG LGP GPRG PG
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 246  EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            + G+PG PGP G  GN G                                    G PGP 
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSK----------------------------------GEPGPA 1420

Query: 306  GPPGPPGPPGPRGPPGPPGTPGSQGLAGER 335
            G  G PG  G RG  G P T  ++G    R
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 70/186 (37%), Positives = 80/186 (43%), Gaps = 33/186 (17%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP GPPG  G PG  G PG  G +GQ G  G  G  G  G PGP  +   +G  G PG  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 257  GPAGNPGPS-----PNSPQ-GALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            G AGNPG       P  P    L  L  P         L S    T   G PG RG PG 
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS----TGNPGEPGLRGIPGS 1016

Query: 311  ------PGPPGPRGP------PGPPGTPGSQGLAGER-----------GTVGPSGEPGVK 347
                  PG  G RG        G PG PG  GL G++           G  GP+G+PG+ 
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 348  GEEGEK 353
            G+ G+K
Sbjct: 1077 GDMGKK 1082



 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 62/167 (37%), Positives = 74/167 (44%), Gaps = 37/167 (22%)

Query: 211 AGPPGSKG----DRGQT---GEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
           A P  SKG    D+GQ    G KG  G  G  GPPG  G  G  G  G PGP GP G PG
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 264 -PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGP--- 319
            P     +G                          ++G+PG  G PG PG PG  GP   
Sbjct: 83  LPGLTGSKGV-----------------------RGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 320 ---PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
              PG  G+ G QG  G  GT+G  G PG  G +G+K A A+ E ++
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  142 bits (358), Expect = 6e-34
 Identities = 86/200 (43%), Positives = 97/200 (48%), Gaps = 26/200 (13%)

Query: 172  PTWNEDF-----LPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGS-----KGDRG 221
            PT  E F     LP AI     +P Q    GP G  G  G PGP GPPGS     KGD+G
Sbjct: 1217 PTGIEGFPGPPGLPGAI-----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG 1271

Query: 222  QTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-------PSPNSPQGALY 274
              G  GP GPPG  G  GP   PG +G PG PG PGP G+PG              G L 
Sbjct: 1272 SMGHPGPKGPPGTAGDMGP---PGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 275  SLQPPTD-KDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAG 333
            S+ PP      G   +        +  +PG  GPPG PG PG +G PGPPG PG+ G  G
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 334  ERGTVGPSGEPGVKGEEGEK 353
             RG  G  G+PG  G  GEK
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEK 1408



 Score =  132 bits (333), Expect = 5e-31
 Identities = 78/174 (44%), Positives = 89/174 (51%), Gaps = 29/174 (16%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR----P 250
           P G  G PG  GP GPAGPPG  G +G+ G +G  G PG  GPPG  G  GE+      P
Sbjct: 597 PPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVP 655

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGPPGP G+PGP    P G   SL    D                  G+PGP G PG 
Sbjct: 656 GPPGPPGPPGHPGPQ--GPPGIPGSLGKCGDP-----------------GLPGPDGEPGI 696

Query: 311 PG-----PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           PG     PPGP+G  G PGT GS G  G+ G  G  G+PG+ G +GE A    G
Sbjct: 697 PGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPG 750



 Score =  127 bits (318), Expect = 3e-29
 Identities = 91/232 (39%), Positives = 101/232 (43%), Gaps = 70/232 (30%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---------PGP 240
            P    P GP G PG  G PG  G PG  GD G  G KG  GPPG+ GP         PGP
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 241  RGLPGEMGRPGPPG-------------PPGPAGNPGP--------SPNSP-----QGALY 274
             G+ G+ GR G PG             PPGP GNPG         +P  P     +GA+ 
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 275  SLQP--PTDKDN--GDSRLASAIV--DTVLAGVPGPRGPPGPPGPPGP------------ 316
               P  PT  +   G   L  AI+   T   G PG RG PG PGPPGP            
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 317  -----RGPPGPPGT------------PGSQGLAGERGTVGPSGEPGVKGEEG 351
                  GP GPPGT            PG+ GL G RG  G  G PGVKGE+G
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322



 Score =  126 bits (316), Expect = 4e-29
 Identities = 81/189 (42%), Positives = 87/189 (46%), Gaps = 38/189 (20%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG----PAGPPGLLGPPGPRGLPGEMGRPGP 252
           G  G PG TG PG  G PG++GD G  GEKG    P G  G+ G PG RG PG  G  G 
Sbjct: 511 GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 253 PGPPGPAGNPGP--------------------SPNSPQGALYSLQPPTDKDNGDSRLASA 292
           PG PG  G PGP                    SP SP G      PP     G+  L   
Sbjct: 571 PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSP-GPAGPAGPPGYGPQGEPGLQGT 629

Query: 293 IVDTVLAGVPG---PRG----------PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  G PG   PRG          PPGPPGPPG  GP GPPG PGS G  G+ G  G
Sbjct: 630 QGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689

Query: 340 PSGEPGVKG 348
           P GEPG+ G
Sbjct: 690 PDGEPGIPG 698



 Score =  124 bits (311), Expect = 2e-28
 Identities = 73/187 (39%), Positives = 84/187 (44%), Gaps = 23/187 (12%)

Query: 197  GPAGPPGQT-----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
            G  G PG +     GPPGP G PG  GD G+ GE G  GPPG LGP GP G PG  G PG
Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPG 1110

Query: 252  PPGPPGPAGNPG----------PSPNSPQG--------ALYSLQPPTDKDNGDSRLASAI 293
             PG PGP G+ G          P    P G            ++    +D          
Sbjct: 1111 LPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKG 1170

Query: 294  VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
               +L   PGPRG PG  G  G RG PG PG PG +G  G+ G  GP+G  G  G  G  
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 354  AATAEGE 360
             A   G+
Sbjct: 1231 GAIIPGQ 1237



 Score =  122 bits (306), Expect = 6e-28
 Identities = 77/200 (38%), Positives = 96/200 (48%), Gaps = 40/200 (20%)

Query: 192  QRRPTGPAGPPG-----QTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            +R  TGP G PG     ++G PG  G PG    +G+ G  G++G  G PG+LGPPG  G+
Sbjct: 831  RRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGV 890

Query: 244  PGEMGRPGPPGPPGPAGNPG----------PSPNSPQGALYSLQPPTDKDN-GDSRLASA 292
             G MG PG  GPPGP GNPG          P     +G   +     DK N G S ++  
Sbjct: 891  IGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHV 950

Query: 293  IVD---------------------TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            I D                       + G+ G +G PGP GPPGPRG  G  G PG  GL
Sbjct: 951  IGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGL 1010

Query: 332  AGERGTVGPSGEPGVKGEEG 351
             G  G++G  G PG KG+ G
Sbjct: 1011 RGIPGSMGNMGMPGSKGKRG 1030



 Score =  121 bits (304), Expect = 1e-27
 Identities = 81/198 (40%), Positives = 97/198 (48%), Gaps = 42/198 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGPRGLPGE--MGRPGP 252
           GP GP G  GP GP+GPPG  G  G +  G +G  G PGL G  G RG PG+  MG PG 
Sbjct: 360 GPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS 419

Query: 253 PG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPG 309
           PG    PG  G+PGP P  P   ++   PP     GD  L   +    + GV GP+G PG
Sbjct: 420 PGCAGSPGLPGSPGP-PGPPGDIVFRKGPP-----GDHGLPGYLGSPGIPGVDGPKGEPG 473

Query: 310 P--------PGPPGPRGPPG------------------PPGTPGSQGLAGERGTVGPSGE 343
                    PGPPG  G PG                   PG+PG+ GL G  G  G  G+
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGD 533

Query: 344 PGVKGEEGEKAATAEGEG 361
           PG+KGE+GE   T + EG
Sbjct: 534 PGLKGEKGE---TLQPEG 548



 Score =  120 bits (301), Expect = 2e-27
 Identities = 82/177 (46%), Positives = 87/177 (49%), Gaps = 11/177 (6%)

Query: 190 PRQRRPTGPAGPPGQTGP---PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P Q+  TGP G PG  GP   PG  G  GSKG RG +G  G +G PGL G PG  G  G 
Sbjct: 60  PGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 247 MGRPGPPGPPGPAGNPGPS-----PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
           +G PG  G  G  G PG       P  P  A    Q        D  L  A  D  L G 
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIEL-DAKGDPGLPGA 178

Query: 302 PGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP--GVKGEEGEKAAT 356
           PGP+G PGPPG PGP GPPGPPG  G  G  G RG  G  GE   G KGE G K  T
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLT 235



 Score =  117 bits (292), Expect = 3e-26
 Identities = 83/218 (38%), Positives = 93/218 (42%), Gaps = 44/218 (20%)

Query: 190 PRQRRPTGPAGPPGQ-----------TGPPGPAGPPGSKGDRGQT-------GEKGPAGP 231
           P    P GPAGPPG             G PG  GPPG  G RG+        G  GP GP
Sbjct: 604 PGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGP 663

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG------PSPNSPQGALYSLQPPTDKDNG 285
           PG  GP GP G+PG +G+ G PG PGP G PG      P P  P+G      P T    G
Sbjct: 664 PGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGF--PGTKGSLG 721

Query: 286 DSRLASAIVDTVLAGVPGPRGPP--------GPPGPPGPRGP---------PGPPGTPGS 328
                         G+PG +G P        G PG PG RG          PG PG PG+
Sbjct: 722 CPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGT 781

Query: 329 QGLAGERGTVGPSGEPGVKGEEGEKAATAEG-EGVQQL 365
            G  G  G  G  G+PG  GE+G      EG  G Q L
Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819



 Score =  116 bits (290), Expect = 5e-26
 Identities = 80/200 (40%), Positives = 87/200 (43%), Gaps = 35/200 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQT--GEKGPAGPPGLLGPPGP------------ 240
           P GP GPPG  G PG  GP G KG  G+   G KG  G  GL GPPGP            
Sbjct: 193 PVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPD 252

Query: 241 -----RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYS--LQPPTDKDN-----GDSR 288
                +G  G+ G  G PGPPGP+G PG S  S +GA     LQ    KD      G   
Sbjct: 253 NRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEG 312

Query: 289 LASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP---------GPPGTPGSQGLAGERGTVG 339
           +        L G  G +G  G  GPPG RGP          G  GTPG  G  G RG  G
Sbjct: 313 VKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQG 372

Query: 340 PSGEPGVKGEEGEKAATAEG 359
           PSG PGV G  G       G
Sbjct: 373 PSGPPGVPGSPGSSRPGLRG 392



 Score =  115 bits (287), Expect = 1e-25
 Identities = 77/210 (36%), Positives = 89/210 (42%), Gaps = 56/210 (26%)

Query: 183 IPLAHPVPRQRRPTGPAGPPGQTGPPGPAG--------------------------PPGS 216
           + ++ PVP    P GP G PG  GPPG  G                          PPG 
Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707

Query: 217 KGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRP--GPPGPPGPAGNPGPSPNSPQG 271
           KGD+G  G KG  G PG +G    PG  GLPG  G P    PG PG  G PG   NS + 
Sbjct: 708 KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767

Query: 272 ALYSLQ--PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP------- 322
               L   P      G+             G+ GPRG PG PGPPG +GPPG        
Sbjct: 768 GEIGLPGLPGLPGTPGNE------------GLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 323 ----PGTPGSQGLAGERGTVGPSGEPGVKG 348
               PG  G +G  G RG  GP G+PG+ G
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845



 Score =  113 bits (282), Expect = 4e-25
 Identities = 81/201 (40%), Positives = 88/201 (43%), Gaps = 40/201 (19%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGP------------------------PGSKGDRGQTG 224
            VP      G  G PG  GPPGP G                         PGSKG RG  G
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 225  EKGPAGPPGLLGPPGPRGLPGEMGRPG-----PPGPPGPAGNPG-PSPNSPQGALYSLQP 278
              G AG PGL   PG  GL G+ G PG      PGPPGP G+PG P     +G +    P
Sbjct: 1034 FPGRAGRPGL---PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 279  PTD-KDNGDSRLASAIVDTVLAGVPGP------RGPPGPPGPPGPRGPPGPPGTPGSQGL 331
            P      G      +     L G PGP      +G  G  GPPG RGPPG PG PGS G 
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 332  AGERGTVGPSGEPGVKGEEGE 352
             G RG  G  G PG  GE+GE
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGE 1171



 Score =  112 bits (281), Expect = 5e-25
 Identities = 83/233 (35%), Positives = 98/233 (42%), Gaps = 69/233 (29%)

Query: 189 VPRQRRPTGPAGPPGQTGPPGPAGPP---------GSKGDRGQTGE-----KGPAGPPGL 234
           +P    P G  GPPG  GP GP GPP         G +G +G  GE     KG  G  GL
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGL 234

Query: 235 LGPPGP-----------------RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGAL--YS 275
            GPPGP                 +G  G+ G  G PGPPGP+G PG S  S +GA     
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG 294

Query: 276 LQPPTDKD-----------NGDSRLASAIVDTVLAGVPGPRGPP---------------- 308
           LQ    KD            G+      + +  + G  G  GPP                
Sbjct: 295 LQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG 354

Query: 309 --GPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             G PGPPGPR      GP GPPG PGS G +   G  G  G PG+KG +GE+
Sbjct: 355 DEGTPGPPGPRGARGPQGPSGPPGVPGSPG-SSRPGLRGAPGWPGLKGSKGER 406



 Score =  111 bits (278), Expect = 1e-24
 Identities = 76/208 (36%), Positives = 86/208 (41%), Gaps = 44/208 (21%)

Query: 197 GPAGPPGQTGPPGPAGP--PGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  G P    P GP  P  PG +G+ G+ GE G  G PGL G PG  GL G  G PG PG
Sbjct: 739 GAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPG 798

Query: 255 PPGPAGNPGPSPNSPQGA-----LYSLQ-----------------PPTDKDNGDSRLASA 292
           PPG  G PG     P+GA     L  L+                 P  D+        S 
Sbjct: 799 PPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858

Query: 293 IV-----------DTVLAGVPGPRGPPGP---------PGPPGPRGPPGPPGTPGSQGLA 332
            +                G PG  GPPG          PG  GP GPPG PGTPG +G  
Sbjct: 859 GIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSP 918

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G  G  G  G PG KGE+G+K      E
Sbjct: 919 GIPGVKGQRGTPGAKGEQGDKGNPGPSE 946



 Score =  109 bits (272), Expect = 6e-24
 Identities = 85/254 (33%), Positives = 100/254 (39%), Gaps = 47/254 (18%)

Query: 151 LEAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQ------ 204
           L+A   P  P    P     PP +     P   P     P    P GP G  G+      
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHK 226

Query: 205 --------TGPPGPAGP--------------PGSKGDRGQTGEKGPAGPPGL-------- 234
                   TGPPGP G                G KGD+G  GE GP GP GL        
Sbjct: 227 GERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSE 286

Query: 235 ---LGPPGPRGLPGEMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDS 287
               G PG +G PG+ G PG PG  G  GN G       +  +G    + PP  +  G +
Sbjct: 287 KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFR--GPT 344

Query: 288 RLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQ--GLAGERGTVGPSGEPG 345
                  +    G PGP GP G  GP GP GPPG PG+PGS   GL G  G  G  G  G
Sbjct: 345 EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKG 404

Query: 346 VKGEEGEKAATAEG 359
            +G  G+ A    G
Sbjct: 405 ERGRPGKDAMGTPG 418



 Score =  108 bits (270), Expect = 1e-23
 Identities = 80/204 (39%), Positives = 89/204 (43%), Gaps = 46/204 (22%)

Query: 197 GPAGPPG----QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL--------GPPGPRGLP 244
           GP GPPG    + GPPG  G PG  G  G  G  GP G PGLL        GPPG  GLP
Sbjct: 433 GPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLP 492

Query: 245 GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV------- 297
           G  G  G PG  G AG  G SP SP        P      GD  L     +T+       
Sbjct: 493 GLHGVKGIPGRQGAAGLKG-SPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG 551

Query: 298 ------LAGVPGPRGPPGPPGPPGPR------------------GPPGPPGTPGSQGLAG 333
                 L G PG +G  G PG PG +                  GPPG PG+PGS G AG
Sbjct: 552 VPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAG 611

Query: 334 ERGT--VGPSGEPGVKGEEGEKAA 355
             G    GP GEPG++G +G   A
Sbjct: 612 PAGPPGYGPQGEPGLQGTQGVPGA 635



 Score =  107 bits (267), Expect = 2e-23
 Identities = 81/227 (35%), Positives = 97/227 (42%), Gaps = 58/227 (25%)

Query: 188 PVPRQRR-PTGPAGPPGQTGPPGPAGP-----------PGSKGDRGQTGEK--------- 226
           P PR  R P GP+GPPG  G PG + P            GSKG+RG+ G+          
Sbjct: 362 PGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPG 421

Query: 227 -----------GPAGPPGLL----GPPGPRGLPGEMGRPGPPGPPGPAGNPG-------- 263
                      GP GPPG +    GPPG  GLPG +G PG PG  GP G PG        
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 264 -PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG----- 315
            P P    G   L+ ++    +  G + L  +       G+PG  G PG  G PG     
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQ-GAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEK 540

Query: 316 -----PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
                P G  G PG PG +G  G +G  G  G PGVKG  G K   A
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA 587



 Score =  107 bits (267), Expect = 2e-23
 Identities = 78/204 (38%), Positives = 92/204 (45%), Gaps = 17/204 (8%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA---------GPPG 215
            P P   P T  +   P  IP    V  QR   G  G  G  G PGP+         G PG
Sbjct: 903  PGPPGNPGTPGQRGSP-GIP---GVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPG 958

Query: 216  SKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALY 274
             KG  G  GEKG  G PG+ G  G +GLPG  G PGP G  G  GNPG P      G++ 
Sbjct: 959  LKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMG 1018

Query: 275  SLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPG-PPGPR-GPPGPPGTPGSQGL 331
            ++  P  K   G            L G+ G +G  G PG   G R GPPGP G PG  G 
Sbjct: 1019 NMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078

Query: 332  AGERGTVGPSGEPGVKGEEGEKAA 355
             G++G +G  G PG  G  G + A
Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGA 1102



 Score =  104 bits (259), Expect = 2e-22
 Identities = 65/172 (37%), Positives = 72/172 (41%), Gaps = 22/172 (12%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP------------------P 238
           G  G PG  G  G  G PG  G+ G  G+KG  GPPG  GP                  P
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           GPRG  G  G  GPPG PG  G+  P      G         ++                
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGC 422

Query: 299 AGVPGPRGPPGPPGPPGP----RGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
           AG PG  G PGPPGPPG     +GPPG  G PG  G  G  G  GP GEPG+
Sbjct: 423 AGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474



 Score =  102 bits (254), Expect = 7e-22
 Identities = 72/199 (36%), Positives = 83/199 (41%), Gaps = 37/199 (18%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPR-------QRRPTGPAGPPGQTGPPGPAGPPGSK 217
            P P   P +       D   + HP P+          P G  G PG  G PGP G PG +
Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312

Query: 218  GDRGQTGEKG------PAGPPGLLGPPGPRGLPGEMGR------PGPPGPPGPAGNPG-- 263
            G  G  GEKG        GPPG +GP GP G+ G+ G       PG PGPPG  G PG  
Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQ 1372

Query: 264  --PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP---RGPPGPPGPPGPRG 318
              P P  P G L    P   K   D +           G PGP   +G  G  G PGP G
Sbjct: 1373 GEPGPPGPPGNLGPCGP-RGKPGKDGK----------PGTPGPAGEKGNKGSKGEPGPAG 1421

Query: 319  PPGPPGTPGSQGLAGERGT 337
              G PG  G +G +G   T
Sbjct: 1422 SDGLPGLKGKRGDSGSPAT 1440



 Score =  102 bits (253), Expect = 9e-22
 Identities = 59/150 (39%), Positives = 65/150 (43%), Gaps = 43/150 (28%)

Query: 195  PTGPAGPPGQTGPPGPA---------GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
            P GP GPPG  G PG           GPPG+ G+ G  GE GP GPPG LGP GPRG PG
Sbjct: 1335 PIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG 1394

Query: 246  EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            + G+PG PGP G  GN G                                    G PGP 
Sbjct: 1395 KDGKPGTPGPAGEKGNKGSK----------------------------------GEPGPA 1420

Query: 306  GPPGPPGPPGPRGPPGPPGTPGSQGLAGER 335
            G  G PG  G RG  G P T  ++G    R
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFVFTR 1450



 Score = 96.7 bits (239), Expect = 4e-20
 Identities = 70/186 (37%), Positives = 80/186 (43%), Gaps = 33/186 (17%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP GPPG  G PG  G PG  G +GQ G  G  G  G  G PGP  +   +G  G PG  
Sbjct: 901  GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960

Query: 257  GPAGNPGPS-----PNSPQ-GALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
            G AGNPG       P  P    L  L  P         L S    T   G PG RG PG 
Sbjct: 961  GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS----TGNPGEPGLRGIPGS 1016

Query: 311  ------PGPPGPRGP------PGPPGTPGSQGLAGER-----------GTVGPSGEPGVK 347
                  PG  G RG        G PG PG  GL G++           G  GP+G+PG+ 
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 348  GEEGEK 353
            G+ G+K
Sbjct: 1077 GDMGKK 1082



 Score = 89.4 bits (220), Expect = 6e-18
 Identities = 62/167 (37%), Positives = 74/167 (44%), Gaps = 37/167 (22%)

Query: 211 AGPPGSKG----DRGQT---GEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
           A P  SKG    D+GQ    G KG  G  G  GPPG  G  G  G  G PGP GP G PG
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 264 -PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGP--- 319
            P     +G                          ++G+PG  G PG PG PG  GP   
Sbjct: 83  LPGLTGSKGV-----------------------RGISGLPGFSGSPGLPGTPGNTGPYGL 119

Query: 320 ---PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
              PG  G+ G QG  G  GT+G  G PG  G +G+K A A+ E ++
Sbjct: 120 VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  140 bits (354), Expect = 2e-33
 Identities = 83/190 (43%), Positives = 93/190 (48%), Gaps = 41/190 (21%)

Query: 195 PTGPAGPPG---------QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLG--------- 236
           P GP GPPG         + GPPG  GPPG KG  G+ G+ G AG PGL G         
Sbjct: 33  PPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDG 92

Query: 237 PPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
           PPGP+G PGE G  GPPGPPG  G   P P    G      PP     G   L      +
Sbjct: 93  PPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGV---SGPP-----GGIGLRGPPGPS 144

Query: 297 VLAGVPGPRGPPGPPGPPG---------------PRGPPGPPGTPGSQGLAGERGTVGPS 341
            L G+PGP GPPGPPG PG               P GPPGPPG PG +G  G +G  G  
Sbjct: 145 GLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEV 204

Query: 342 GEPGVKGEEG 351
           G+ G KG+ G
Sbjct: 205 GKDGEKGDPG 214



 Score =  136 bits (343), Expect = 3e-32
 Identities = 90/220 (40%), Positives = 104/220 (47%), Gaps = 66/220 (30%)

Query: 195 PTGPAGPPGQTGPPGPAGPPG--SKGDRGQTGEKGPAGPPG---LLGPPGPRGLPGEMGR 249
           P GP G PG+ G  GP GPPG   KG  G  GE G +GPPG   L GPPGP GLPG    
Sbjct: 93  PPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG---L 149

Query: 250 PGPPGPPGPAGNPG----------------PSPNSPQGALYSLQPPT-----------DK 282
           PGPPGPPGP G+PG                P P  P G +   + PT           D 
Sbjct: 150 PGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPG-MPGFKGPTGYKGEQGEVGKDG 208

Query: 283 DNGDSRLA--SAIVDTV-------LAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAG 333
           + GD      + +  +V       L G+PGP GPPG  GP G RGPPG PG PG  G  G
Sbjct: 209 EKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG 268

Query: 334 ER---------------------GTVGPSGEPGVKGEEGE 352
           ER                     G  GPSGEPG+ G++G+
Sbjct: 269 ERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQ 308



 Score =  135 bits (339), Expect = 1e-31
 Identities = 79/184 (42%), Positives = 90/184 (48%), Gaps = 34/184 (18%)

Query: 204 QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG 263
           + G PGP GPPG  G  GQ G  G AGPPGL GPPGP+G PG+ G+PG  G PG  G  G
Sbjct: 27  RVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDG 86

Query: 264 -------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP---RGPPGP--- 310
                  P P    G   SL PP     G   L     +  ++G PG    RGPPGP   
Sbjct: 87  LTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGL 146

Query: 311 ---PGPPGPRGPPG------------------PPGTPGSQGLAGERGTVGPSGEPGVKGE 349
              PGPPGP GPPG                  PPG PG  G+ G +G  G  GE G  G+
Sbjct: 147 PGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGK 206

Query: 350 EGEK 353
           +GEK
Sbjct: 207 DGEK 210



 Score =  122 bits (305), Expect = 8e-28
 Identities = 77/193 (39%), Positives = 93/193 (48%), Gaps = 13/193 (6%)

Query: 179 LPDAIPLAHP-----VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPG 233
           LP ++ L  P     +P    P G  GP G  GPPG  G PG  GDRG+ G +G  GP G
Sbjct: 221 LPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKG 280

Query: 234 LLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKD-NGDSRLAS 291
            LG PGP+G PG  G  G PG PG  G  G P  +  +G       P +K  NG   L  
Sbjct: 281 DLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPG 340

Query: 292 AIV------DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPG 345
                    +   AG  G  GP G PG PG  G PG  G  G +G AG  G  GP G PG
Sbjct: 341 RAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPG 400

Query: 346 VKGEEGEKAATAE 358
           V+G +G+K +  +
Sbjct: 401 VRGFQGQKGSMGD 413



 Score =  121 bits (304), Expect = 1e-27
 Identities = 80/194 (41%), Positives = 91/194 (46%), Gaps = 14/194 (7%)

Query: 164 LPAPESTP-PTWNEDFLPD-AIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRG 221
           LP P   P P  +   LP+ A  L  P      P GP GPPG  G  GP G  G +G+ G
Sbjct: 149 LPGPPGPPGPPGHPGVLPEGATDLQCP---SICPPGPPGPPGMPGFKGPTGYKGEQGEVG 205

Query: 222 QTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGP----SPNSPQGALYSLQ 277
           + GEKG  GPPG  G PG  GL G  G  G PGP GP G+ GP     P    GA     
Sbjct: 206 KDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGA----- 260

Query: 278 PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGT 337
           P    D G+             G PGP+G PG  GP G  G PG  G  G  GL G++G 
Sbjct: 261 PGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGE 320

Query: 338 VGPSGEPGVKGEEG 351
            G +G PG KG  G
Sbjct: 321 AGRNGAPGEKGPNG 334



 Score =  120 bits (301), Expect = 2e-27
 Identities = 71/172 (41%), Positives = 88/172 (51%), Gaps = 6/172 (3%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  G  G+ GP G  GP G  G RG+ G KG  GP G  G  G  G PG +G  G PG P
Sbjct: 448 GLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVP 507

Query: 257 GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV---PGPRGPPGPPG 312
           G  G PG P   + +  +  L      +   ++LA+ +   +  G    PGP GPPGPPG
Sbjct: 508 GITGKPGVPGKEASEQRIRELCGGMISEQ-IAQLAAHLRKPLAPGSIGRPGPAGPPGPPG 566

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG-EGVQ 363
           PPG  G PG  G PG +G  GE G  GP G  G +G++G   A  +G EG Q
Sbjct: 567 PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQ 618



 Score =  116 bits (290), Expect = 5e-26
 Identities = 70/181 (38%), Positives = 86/181 (47%), Gaps = 21/181 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G AGP G+ G PG AG PG +G+ G  G  G  GP G  G PG RG  G+ G  G PG P
Sbjct: 358 GEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLP 417

Query: 257 GP------AGNPGP----SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
           GP       G+ GP     P   QG   S   P DK            +   +G+ GP+G
Sbjct: 418 GPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKG-----------ELGPSGLVGPKG 466

Query: 307 PPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLR 366
             G  G  GP+G  GP GT G QG+ G  G +G  G PGV G  G+     +    Q++R
Sbjct: 467 ESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIR 526

Query: 367 E 367
           E
Sbjct: 527 E 527



 Score =  114 bits (285), Expect = 2e-25
 Identities = 68/157 (43%), Positives = 78/157 (49%), Gaps = 13/157 (8%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  GP G  G PG AG  G KG+RG+ GE G AGP G  G PG  G+PGE G  G  G  
Sbjct: 328 GEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSA 387

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G  GP P +P    +  Q  +  D G            L G  G RG  G  GP G 
Sbjct: 388 GALGPQGP-PGAPGVRGFQGQKGSMGDPG------------LPGPQGLRGDVGDRGPGGA 434

Query: 317 RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            GP G  G  GS GL G++G +GPSG  G KGE G +
Sbjct: 435 AGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSR 471



 Score =  103 bits (256), Expect = 4e-22
 Identities = 73/223 (32%), Positives = 89/223 (39%), Gaps = 60/223 (26%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG--------- 245
           P+G  GP G++G  G  GP G++G  G +G +G  GPPG LG  G  G+PG         
Sbjct: 458 PSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPG 517

Query: 246 ----------------------------------EMGRPGPPGPPGPAGNPG-------- 263
                                              +GRPGP GPPGP G PG        
Sbjct: 518 KEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGAR 577

Query: 264 --PSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPR--G 318
             P    P G L    P  ++ D GD   A A +D    G  G +GP GP G PG    G
Sbjct: 578 GPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLD----GPEGDQGPQGPQGVPGTSKDG 633

Query: 319 PPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
             G PG PG  G  G  G +G  G PG+      + A   G G
Sbjct: 634 QDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQGAVLGGVG 676



 Score =  102 bits (255), Expect = 5e-22
 Identities = 66/155 (42%), Positives = 71/155 (45%), Gaps = 26/155 (16%)

Query: 193 RRPTGPA--GPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
           R+P  P   G PG  GPPGP GPPGS G  G  G  G  GP G LG PGPRG  G+ G  
Sbjct: 545 RKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDK 604

Query: 251 GPPGP--PGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
           G  G    GP G+ G  P  PQG      P T KD  D             G PG  GPP
Sbjct: 605 GAAGAGLDGPEGDQG--PQGPQGV-----PGTSKDGQD-------------GAPGEPGPP 644

Query: 309 GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGE 343
           G PG PG  G  G PG   +    G    +G  GE
Sbjct: 645 GDPGLPGAIGAQGTPGICDTSACQG--AVLGGVGE 677



 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 34/76 (44%), Positives = 37/76 (48%), Gaps = 18/76 (23%)

Query: 298 LAGVPGPRGPPGP---------------PGPPGPRGPPGPPGTPGS---QGLAGERGTVG 339
           L G PGP GPPG                PGPPGP+G PG PG PG     GL G  G  G
Sbjct: 30  LPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTG 89

Query: 340 PSGEPGVKGEEGEKAA 355
             G PG KG  GE+ +
Sbjct: 90  RDGPPGPKGAPGERGS 105



 Score = 56.2 bits (134), Expect = 6e-08
 Identities = 25/47 (53%), Positives = 27/47 (57%)

Query: 312 GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           G PGP GPPGPPG PG  G+ GE G  G  G PG KG  G+     E
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75



 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 51/160 (31%), Positives = 59/160 (36%), Gaps = 34/160 (21%)

Query: 117 PGFTGSNCDEECMNCTRLSDMSERLTTLEAKVLLLEAAERPSSPDNDLPAPESTPPTWNE 176
           PG  G    E+ +       +SE++  L A    L     P S     PA    PP    
Sbjct: 513 PGVPGKEASEQRIRELCGGMISEQIAQLAAH---LRKPLAPGSIGRPGPAGPPGPPG--- 566

Query: 177 DFLPDAI--PLAHPVPRQRRPTGPAGPPGQTG--------------------PPGPAGPP 214
              P +I  P A   P  R PTG  G PG  G                      GP GP 
Sbjct: 567 --PPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQ 624

Query: 215 GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  G    T + G  G PG  GPPG  GLPG +G  G PG
Sbjct: 625 GVPG----TSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  140 bits (352), Expect = 3e-33
 Identities = 78/171 (45%), Positives = 87/171 (50%), Gaps = 29/171 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GPAG PG+ G  G  G PG KG +G  GE GP GPPGL GP G  G+ G  G PGP G
Sbjct: 1127 PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1186

Query: 255  PPGPAGNPG-------PSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG 306
              G  G  G       P P  P G      PP +K +NGD                GP G
Sbjct: 1187 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV---------------GPMG 1231

Query: 307  PPGPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PPGPPGP GP+      GP GPPG+ GS G  GE+G  G +G PG  GE G
Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282



 Score =  138 bits (348), Expect = 9e-33
 Identities = 74/161 (45%), Positives = 82/161 (50%), Gaps = 22/161 (13%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE---MGRPGP- 252
            G  G PG+ G PGP G  G  G +G+ GEKG AGPPG  GPPG +G PG+    G PGP 
Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323

Query: 253  --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              PG PGP G PGP+     G           D G+        D    G PGP G  GP
Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGG----------DKGEDG------DPGQPGPPGPSGEAGP 1367

Query: 311  PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PGPPG RGPPG  G  G QG  G +G  G  G PG  G  G
Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1408



 Score =  138 bits (348), Expect = 9e-33
 Identities = 85/212 (40%), Positives = 102/212 (48%), Gaps = 42/212 (19%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEK---------------GPAGPPGL 234
            P Q  P GP+G  G  GPPG  GPPG+ G  G+ GEK               GP GP G 
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1412

Query: 235  LGPPGP------------RGLPGEMGRPGPPGPPGPAGNPG--PSPNSP-----QGALYS 275
             G PGP            +GLPG  G+ GPPGP GP G PG    P S       G +  
Sbjct: 1413 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1472

Query: 276  LQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGE 334
            + PP ++ + GD  L          G PG +G  G PGP GP GPPGPPG PG QG  G 
Sbjct: 1473 IGPPGEQGEKGDRGLPGT------QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526

Query: 335  RGTVGPSGEPGVKGEEGEKAATA-EGEGVQQL 365
            +G+ GP+G+ G  G  G   +    GE +Q L
Sbjct: 1527 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1558



 Score =  137 bits (344), Expect = 3e-32
 Identities = 74/161 (45%), Positives = 87/161 (54%), Gaps = 22/161 (13%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GP G TG PGP G PGS G +G++G+ GP GP G+ GPPGP G PG+ GRPG  G  
Sbjct: 541 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 600

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G PG   +     L  L  P DK +   R              GP+GPPGPPG  G 
Sbjct: 601 GMPGEPGAKGDRGFDGLPGL--PGDKGHRGER--------------GPQGPPGPPGDDGM 644

Query: 317 R------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           R      GP G PG  G +GL G RGT G  G+PG+ G +G
Sbjct: 645 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 685



 Score =  137 bits (344), Expect = 3e-32
 Identities = 81/188 (43%), Positives = 95/188 (50%), Gaps = 27/188 (14%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGS------KGDRGQT---GEKGPAGPPGLLGPPGP 240
            P +R P GP GP G  GP GP GPPG        G RG+T   G+ GP GP G++GP GP
Sbjct: 927  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986

Query: 241  RGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G  G +G  G PGPPGP G  G P     +GA          D G   ++       L 
Sbjct: 987  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA--------KGDPGPQGISGKDGPAGLR 1038

Query: 300  GVPGPRGPPGPPGPP------GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVK---GEE 350
            G PG RG PG  G P      GP+GPPGP G+PG +G AG  G +G  G PG +   G  
Sbjct: 1039 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1098

Query: 351  GEKAATAE 358
            GEK A  E
Sbjct: 1099 GEKGAPGE 1106



 Score =  136 bits (343), Expect = 3e-32
 Identities = 77/170 (45%), Positives = 88/170 (51%), Gaps = 31/170 (18%)

Query: 192  QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP- 250
            +R   GP GPPG+ G PG AG  G+KGD G  G  G  GP GL G PG RGLPG  G P 
Sbjct: 995  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1054

Query: 251  -----GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
                 GP GPPGP G+PG                   + G +  A  I    L G PGP+
Sbjct: 1055 LKGGEGPQGPPGPVGSPG-------------------ERGSAGTAGPI---GLPGRPGPQ 1092

Query: 306  GPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            GPPGP    G PG +GP GP G  G QG  G  G  GP+G PG  G++GE
Sbjct: 1093 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1142



 Score =  134 bits (338), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 89/180 (49%), Gaps = 18/180 (10%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG--------- 245
            P G  G  G+ GPPG AGPPG+KG  G  G KG  GP G  G PGP G PG         
Sbjct: 1286 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1345

Query: 246  ---EMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
               E G PG PGPPGP+G  G    P    P GA  +     +K  G    A A      
Sbjct: 1346 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGK 1403

Query: 299  AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
             G  GP+GP G PGP G RG PGP G  G  G AG+ G  GP G PG+ G +G+  +  E
Sbjct: 1404 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE 1463



 Score =  134 bits (336), Expect = 2e-31
 Identities = 79/185 (42%), Positives = 95/185 (51%), Gaps = 35/185 (18%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP------AGPPGLLGPPGPRGLPGEMGRP 250
           G  G  G+ GP GP GPPG  G RG+ GE GP      AGP GLLGP G  G PG+ G  
Sbjct: 622 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           G  GPPGP GN G     PQG      PP  + N   +           G+PGP+GP GP
Sbjct: 682 GVDGPPGPKGNMG-----PQG---EPGPPGQQGNPGPQ-----------GLPGPQGPIGP 722

Query: 311 PGPPGPRGPP---------GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
           PG  GP+G P         GPPG PG +G +GE+G +GP G  G  G  G +      +G
Sbjct: 723 PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG-ADG 781

Query: 362 VQQLR 366
           V+ L+
Sbjct: 782 VRGLK 786



 Score =  134 bits (336), Expect = 2e-31
 Identities = 87/215 (40%), Positives = 92/215 (42%), Gaps = 51/215 (23%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPP---------GLLGPPGP 240
            P +R   G AGP G  G PGP GPPG  G++G  GEKGP GP          GL GP GP
Sbjct: 1071 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1130

Query: 241  RGLPGE------------------MGRPGPPGPP---GPAGNPG-------PSPNSPQGA 272
             G PGE                   G  GPPGPP   GP G PG       P P   QG 
Sbjct: 1131 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1190

Query: 273  LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---------GPPGPPGPPGPRGPPGPP 323
                      D G            L G+PGP          GP GPPGPPGPRGP GP 
Sbjct: 1191 F-----GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1245

Query: 324  GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
            G  G QG  G  G+VG  GE G  GE G      E
Sbjct: 1246 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1280



 Score =  132 bits (331), Expect = 8e-31
 Identities = 76/174 (43%), Positives = 87/174 (50%), Gaps = 13/174 (7%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP---------G 245
           P G  GPPGQ G PGP G PG +G  G  GEKGP G PGL G PG  G P         G
Sbjct: 695 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 754

Query: 246 EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL---AGVP 302
           E G  GPPGP GP G PGP        +  L+  +  + G+        D  L    G  
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGFKGDMGLKGDRGEV 813

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
           G  GP G  GP GP+G  GP G PG  G AGE+G +G  G PG  G +G K +T
Sbjct: 814 GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 867



 Score =  131 bits (329), Expect = 1e-30
 Identities = 71/156 (45%), Positives = 79/156 (50%), Gaps = 7/156 (4%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G AG PG  G  GP GP GS+G RG TG+ GP G  G  GPPGP G  G  G  GP G P
Sbjct: 883  GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942

Query: 257  GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
            GP G PGP             P      G++            GV GP+GP G  GP G 
Sbjct: 943  GPKGPPGPPGKDG-------LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 995

Query: 317  RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            RG PGPPG PG QGL G  G  G  G+PG +G  G+
Sbjct: 996  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/182 (41%), Positives = 84/182 (46%), Gaps = 27/182 (14%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRPG 251
            P G  G  G  GP GP GPPG +G +G  G  GP GPPG +G     G +G PGE G PG
Sbjct: 1217 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1276

Query: 252  PP------------------GPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRL 289
            PP                  GPPG AG PG    P  + P+G    +  P D   G    
Sbjct: 1277 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGE 1334

Query: 290  ASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
                    + G  G  G PG PGPPGP G  GPPG PG +G  G  G  G  GE G KGE
Sbjct: 1335 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394

Query: 350  EG 351
             G
Sbjct: 1395 AG 1396



 Score =  125 bits (314), Expect = 8e-29
 Identities = 69/160 (43%), Positives = 82/160 (51%), Gaps = 18/160 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG  G PG AG  G  G +G  G +G  GPPG  G PGP+GLPG  G  GPPG  
Sbjct: 667 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 726

Query: 257 GPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           GP G PG    P  + P G      P  +  +G+             G PGP+GP G PG
Sbjct: 727 GPQGKPGLAGLPGADGPPG-----HPGKEGQSGEKG---------ALGPPGPQGPIGYPG 772

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           P G +G  G  G  GS+G  GE G  G  G+ G+KG+ GE
Sbjct: 773 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGE 812



 Score =  125 bits (314), Expect = 8e-29
 Identities = 79/183 (43%), Positives = 86/183 (46%), Gaps = 31/183 (16%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G  G  GP G AGP G  G  GQ GEKG  G PGL G PG +G  G  G PG PG  
Sbjct: 817 GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 876

Query: 257 GP------AGNPGP----SPNSPQGALYSLQP-----PTDKDNGDSRLASAIVDTVLAGV 301
           G       AG PGP     P  P+G+  +  P     P     GD             G 
Sbjct: 877 GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP----------PGP 926

Query: 302 PGPRGPPGPPGP---PGPRGPPGPP---GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PG RGP GP GP   PGP+GPPGPP   G PG  G  GE G  G +G PG  G  G +  
Sbjct: 927 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986

Query: 356 TAE 358
           T E
Sbjct: 987 TGE 989



 Score =  125 bits (314), Expect = 8e-29
 Identities = 73/176 (41%), Positives = 86/176 (48%), Gaps = 27/176 (15%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P +R   G  G PG  G  GP GPP   GS G+RG  G  GP G PG  GP GP G  GE
Sbjct: 1041 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1100

Query: 247  MGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G PG  GP GPAG  G       P P  P G+     P  D D G+             
Sbjct: 1101 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS-----PGEDGDKGE------------I 1143

Query: 300  GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G PG +G  G  G  GP GPPG  G  G+ G+AG  G  GP G+ G+ G++G++ A
Sbjct: 1144 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199



 Score =  125 bits (313), Expect = 1e-28
 Identities = 81/195 (41%), Positives = 94/195 (48%), Gaps = 39/195 (20%)

Query: 192 QRRPTGPAGPP------GQTGPPGPAGPPGSKGDRGQTGEK---GPAGPPGLLGPPGPRG 242
           +R P GP GPP      G+ G  GP G PG  G RG  G +   G  G PG+ G  GP G
Sbjct: 629 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSP-NSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             G MG  G PGPPG  GNPGP     PQG    + PP +K               LAG+
Sbjct: 689 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGK--------PGLAGL 737

Query: 302 PGPRGPPGPP------------GPPGPRGP---PGPPGTPGSQGLAGERGTVGPSGE--- 343
           PG  GPPG P            GPPGP+GP   PGP G  G+ G+ G +G+ G  GE   
Sbjct: 738 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 797

Query: 344 PGVKGEEGEKAATAE 358
           PG KG+ G K    E
Sbjct: 798 PGFKGDMGLKGDRGE 812



 Score =  115 bits (289), Expect = 6e-26
 Identities = 80/219 (36%), Positives = 100/219 (45%), Gaps = 24/219 (10%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAG--PPGQT--GP 207
           E  ++P+SP N+    E  P    E  + +     H    ++   G      PG    GP
Sbjct: 400 EYEDKPTSPPNE----EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP 455

Query: 208 PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP-------GPAG 260
           PGPAGP G  G  G  G  GP G PG  GPPG  GLPG  G PGPPG         G  G
Sbjct: 456 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 515

Query: 261 NPGPSPNSP--------QGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           + GP+ ++         Q A  +L+ P     G +     +     +G  G  G PGP G
Sbjct: 516 SKGPTISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSSGAKGESGDPGPQG 574

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           P G +GPPGP G PG +G  G  G  G  GEPG KG+ G
Sbjct: 575 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 613



 Score =  112 bits (281), Expect = 5e-25
 Identities = 79/206 (38%), Positives = 94/206 (45%), Gaps = 33/206 (16%)

Query: 184 PLAHPVPRQ-------RRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG------EKGPAG 230
           P+ +P PR        R   G  G  G+ G PG  G  G KGDRG+ G      E GP G
Sbjct: 767 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 826

Query: 231 PPGLLGP---PGPRGLPGEMGR---------PGPPGPPGPAGNPG-PSPNSPQGAL-YSL 276
           P G  GP   PGP G  GE G+         PG  GP G  G PG P  N  +GA   + 
Sbjct: 827 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 886

Query: 277 QPPTDKDNGDSRLASAIVDTVLAGVPGPR------GPPGPPGPPGPRGPPGPPGTPGSQG 330
           +P      G +    +       G PGP+      GPPGPPG  GP+GP GP G PG +G
Sbjct: 887 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 946

Query: 331 LAGERGTVGPSGEPGVKGEEGEKAAT 356
             G  G  G  G PG +GE G +  T
Sbjct: 947 PPGPPGKDGLPGHPGQRGETGFQGKT 972



 Score =  100 bits (250), Expect = 2e-21
 Identities = 73/165 (44%), Positives = 76/165 (46%), Gaps = 43/165 (26%)

Query: 184  PLAHPVPRQRR----PTGPAGPPG---QTGPPGPAGPPGS---KGDRGQTGEKGPAGPPG 233
            P   P P   R    P G  G PG   Q GPPGP GPPG    KGD G  GEKG  G  G
Sbjct: 1412 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1471

Query: 234  LLGPPGP------RGLPGEMGRPGP------PGPPGPAGNPGP----SPNSPQGALYSLQ 277
            L+GPPG       RGLPG  G PG       PGP GP G PGP     P  P+G   S  
Sbjct: 1472 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG 1531

Query: 278  PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP 322
            P   K  GDS            G+PGP   PG PGPPG    P P
Sbjct: 1532 PAGQK--GDS------------GLPGP---PGSPGPPGEVIQPLP 1559



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 38/98 (38%), Positives = 47/98 (47%), Gaps = 16/98 (16%)

Query: 155  ERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            E+    D  LP  + +P    +  +P                GPAGP G  GPPG  GP 
Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIP----------------GPAGPLGPPGPPGLPGPQ 1521

Query: 215  GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP 252
            G KG++G TG  G  G  GL GPPG  G PGE+ +P P
Sbjct: 1522 GPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 65/204 (31%), Positives = 71/204 (34%), Gaps = 83/204 (40%)

Query: 194 RPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
           +PT P  P  + GP  PA       S    G  GEKG  G P ++ P    G+  E    
Sbjct: 404 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVE---- 453

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGP GPAG  GP           LQ PT                   G PG  G  GP
Sbjct: 454 GPPGPAGPAGIMGPP---------GLQGPT-------------------GPPGDPGDRGP 485

Query: 311 PGP---PGPRGPPGPPGT---------------------------------------PGS 328
           PG    PG  G PGPPGT                                       PG 
Sbjct: 486 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 545

Query: 329 QGLAGERGTVGPSGEPGVKGEEGE 352
            GL G  G VG  G  G KGE G+
Sbjct: 546 MGLTGRPGPVGGPGSSGAKGESGD 569



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 183  IPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
            +P     P  +   G  GP G  GPPGP G PG +G +G  G  GPAG  G  G PGP  
Sbjct: 1487 LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP-- 1544

Query: 243  LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDN 284
                   PG PGPPG    P P  +S +   ++     D D+
Sbjct: 1545 -------PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADD 1579


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  140 bits (352), Expect = 3e-33
 Identities = 78/171 (45%), Positives = 87/171 (50%), Gaps = 29/171 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GPAG PG+ G  G  G PG KG +G  GE GP GPPGL GP G  G+ G  G PGP G
Sbjct: 1076 PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1135

Query: 255  PPGPAGNPG-------PSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG 306
              G  G  G       P P  P G      PP +K +NGD                GP G
Sbjct: 1136 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV---------------GPMG 1180

Query: 307  PPGPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PPGPPGP GP+      GP GPPG+ GS G  GE+G  G +G PG  GE G
Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231



 Score =  138 bits (348), Expect = 9e-33
 Identities = 74/161 (45%), Positives = 82/161 (50%), Gaps = 22/161 (13%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE---MGRPGP- 252
            G  G PG+ G PGP G  G  G +G+ GEKG AGPPG  GPPG +G PG+    G PGP 
Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272

Query: 253  --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              PG PGP G PGP+     G           D G+        D    G PGP G  GP
Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGG----------DKGEDG------DPGQPGPPGPSGEAGP 1316

Query: 311  PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PGPPG RGPPG  G  G QG  G +G  G  G PG  G  G
Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1357



 Score =  138 bits (348), Expect = 9e-33
 Identities = 85/212 (40%), Positives = 102/212 (48%), Gaps = 42/212 (19%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEK---------------GPAGPPGL 234
            P Q  P GP+G  G  GPPG  GPPG+ G  G+ GEK               GP GP G 
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1361

Query: 235  LGPPGP------------RGLPGEMGRPGPPGPPGPAGNPG--PSPNSP-----QGALYS 275
             G PGP            +GLPG  G+ GPPGP GP G PG    P S       G +  
Sbjct: 1362 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1421

Query: 276  LQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGE 334
            + PP ++ + GD  L          G PG +G  G PGP GP GPPGPPG PG QG  G 
Sbjct: 1422 IGPPGEQGEKGDRGLPGT------QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475

Query: 335  RGTVGPSGEPGVKGEEGEKAATA-EGEGVQQL 365
            +G+ GP+G+ G  G  G   +    GE +Q L
Sbjct: 1476 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1507



 Score =  137 bits (344), Expect = 3e-32
 Identities = 74/161 (45%), Positives = 87/161 (54%), Gaps = 22/161 (13%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GP G TG PGP G PGS G +G++G+ GP GP G+ GPPGP G PG+ GRPG  G  
Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G PG   +     L  L  P DK +   R              GP+GPPGPPG  G 
Sbjct: 550 GMPGEPGAKGDRGFDGLPGL--PGDKGHRGER--------------GPQGPPGPPGDDGM 593

Query: 317 R------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           R      GP G PG  G +GL G RGT G  G+PG+ G +G
Sbjct: 594 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 634



 Score =  137 bits (344), Expect = 3e-32
 Identities = 81/188 (43%), Positives = 95/188 (50%), Gaps = 27/188 (14%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGS------KGDRGQT---GEKGPAGPPGLLGPPGP 240
            P +R P GP GP G  GP GP GPPG        G RG+T   G+ GP GP G++GP GP
Sbjct: 876  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935

Query: 241  RGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G  G +G  G PGPPGP G  G P     +GA          D G   ++       L 
Sbjct: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA--------KGDPGPQGISGKDGPAGLR 987

Query: 300  GVPGPRGPPGPPGPP------GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVK---GEE 350
            G PG RG PG  G P      GP+GPPGP G+PG +G AG  G +G  G PG +   G  
Sbjct: 988  GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1047

Query: 351  GEKAATAE 358
            GEK A  E
Sbjct: 1048 GEKGAPGE 1055



 Score =  136 bits (343), Expect = 3e-32
 Identities = 77/170 (45%), Positives = 88/170 (51%), Gaps = 31/170 (18%)

Query: 192  QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP- 250
            +R   GP GPPG+ G PG AG  G+KGD G  G  G  GP GL G PG RGLPG  G P 
Sbjct: 944  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1003

Query: 251  -----GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
                 GP GPPGP G+PG                   + G +  A  I    L G PGP+
Sbjct: 1004 LKGGEGPQGPPGPVGSPG-------------------ERGSAGTAGPI---GLPGRPGPQ 1041

Query: 306  GPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            GPPGP    G PG +GP GP G  G QG  G  G  GP+G PG  G++GE
Sbjct: 1042 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091



 Score =  134 bits (338), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 89/180 (49%), Gaps = 18/180 (10%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG--------- 245
            P G  G  G+ GPPG AGPPG+KG  G  G KG  GP G  G PGP G PG         
Sbjct: 1235 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1294

Query: 246  ---EMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
               E G PG PGPPGP+G  G    P    P GA  +     +K  G    A A      
Sbjct: 1295 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGK 1352

Query: 299  AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
             G  GP+GP G PGP G RG PGP G  G  G AG+ G  GP G PG+ G +G+  +  E
Sbjct: 1353 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE 1412



 Score =  134 bits (336), Expect = 2e-31
 Identities = 79/185 (42%), Positives = 95/185 (51%), Gaps = 35/185 (18%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP------AGPPGLLGPPGPRGLPGEMGRP 250
           G  G  G+ GP GP GPPG  G RG+ GE GP      AGP GLLGP G  G PG+ G  
Sbjct: 571 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           G  GPPGP GN G     PQG      PP  + N   +           G+PGP+GP GP
Sbjct: 631 GVDGPPGPKGNMG-----PQG---EPGPPGQQGNPGPQ-----------GLPGPQGPIGP 671

Query: 311 PGPPGPRGPP---------GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
           PG  GP+G P         GPPG PG +G +GE+G +GP G  G  G  G +      +G
Sbjct: 672 PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG-ADG 730

Query: 362 VQQLR 366
           V+ L+
Sbjct: 731 VRGLK 735



 Score =  134 bits (336), Expect = 2e-31
 Identities = 87/215 (40%), Positives = 92/215 (42%), Gaps = 51/215 (23%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPP---------GLLGPPGP 240
            P +R   G AGP G  G PGP GPPG  G++G  GEKGP GP          GL GP GP
Sbjct: 1020 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1079

Query: 241  RGLPGE------------------MGRPGPPGPP---GPAGNPG-------PSPNSPQGA 272
             G PGE                   G  GPPGPP   GP G PG       P P   QG 
Sbjct: 1080 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1139

Query: 273  LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---------GPPGPPGPPGPRGPPGPP 323
                      D G            L G+PGP          GP GPPGPPGPRGP GP 
Sbjct: 1140 F-----GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1194

Query: 324  GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
            G  G QG  G  G+VG  GE G  GE G      E
Sbjct: 1195 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1229



 Score =  132 bits (331), Expect = 8e-31
 Identities = 76/174 (43%), Positives = 87/174 (50%), Gaps = 13/174 (7%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP---------G 245
           P G  GPPGQ G PGP G PG +G  G  GEKGP G PGL G PG  G P         G
Sbjct: 644 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 703

Query: 246 EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL---AGVP 302
           E G  GPPGP GP G PGP        +  L+  +  + G+        D  L    G  
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGFKGDMGLKGDRGEV 762

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
           G  GP G  GP GP+G  GP G PG  G AGE+G +G  G PG  G +G K +T
Sbjct: 763 GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 816



 Score =  131 bits (329), Expect = 1e-30
 Identities = 71/156 (45%), Positives = 79/156 (50%), Gaps = 7/156 (4%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G AG PG  G  GP GP GS+G RG TG+ GP G  G  GPPGP G  G  G  GP G P
Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           GP G PGP             P      G++            GV GP+GP G  GP G 
Sbjct: 892 GPKGPPGPPGKDG-------LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 944

Query: 317 RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           RG PGPPG PG QGL G  G  G  G+PG +G  G+
Sbjct: 945 RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/182 (41%), Positives = 84/182 (46%), Gaps = 27/182 (14%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRPG 251
            P G  G  G  GP GP GPPG +G +G  G  GP GPPG +G     G +G PGE G PG
Sbjct: 1166 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1225

Query: 252  PP------------------GPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRL 289
            PP                  GPPG AG PG    P  + P+G    +  P D   G    
Sbjct: 1226 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGE 1283

Query: 290  ASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
                    + G  G  G PG PGPPGP G  GPPG PG +G  G  G  G  GE G KGE
Sbjct: 1284 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343

Query: 350  EG 351
             G
Sbjct: 1344 AG 1345



 Score =  125 bits (314), Expect = 8e-29
 Identities = 69/160 (43%), Positives = 82/160 (51%), Gaps = 18/160 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG  G PG AG  G  G +G  G +G  GPPG  G PGP+GLPG  G  GPPG  
Sbjct: 616 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 675

Query: 257 GPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           GP G PG    P  + P G      P  +  +G+             G PGP+GP G PG
Sbjct: 676 GPQGKPGLAGLPGADGPPG-----HPGKEGQSGEKG---------ALGPPGPQGPIGYPG 721

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           P G +G  G  G  GS+G  GE G  G  G+ G+KG+ GE
Sbjct: 722 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGE 761



 Score =  125 bits (314), Expect = 8e-29
 Identities = 79/183 (43%), Positives = 86/183 (46%), Gaps = 31/183 (16%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G  G  GP G AGP G  G  GQ GEKG  G PGL G PG +G  G  G PG PG  
Sbjct: 766 GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 825

Query: 257 GP------AGNPGP----SPNSPQGALYSLQP-----PTDKDNGDSRLASAIVDTVLAGV 301
           G       AG PGP     P  P+G+  +  P     P     GD             G 
Sbjct: 826 GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP----------PGP 875

Query: 302 PGPRGPPGPPGP---PGPRGPPGPP---GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PG RGP GP GP   PGP+GPPGPP   G PG  G  GE G  G +G PG  G  G +  
Sbjct: 876 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935

Query: 356 TAE 358
           T E
Sbjct: 936 TGE 938



 Score =  125 bits (314), Expect = 8e-29
 Identities = 73/176 (41%), Positives = 86/176 (48%), Gaps = 27/176 (15%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P +R   G  G PG  G  GP GPP   GS G+RG  G  GP G PG  GP GP G  GE
Sbjct: 990  PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1049

Query: 247  MGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G PG  GP GPAG  G       P P  P G+     P  D D G+             
Sbjct: 1050 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS-----PGEDGDKGE------------I 1092

Query: 300  GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G PG +G  G  G  GP GPPG  G  G+ G+AG  G  GP G+ G+ G++G++ A
Sbjct: 1093 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148



 Score =  125 bits (313), Expect = 1e-28
 Identities = 81/195 (41%), Positives = 94/195 (48%), Gaps = 39/195 (20%)

Query: 192 QRRPTGPAGPP------GQTGPPGPAGPPGSKGDRGQTGEK---GPAGPPGLLGPPGPRG 242
           +R P GP GPP      G+ G  GP G PG  G RG  G +   G  G PG+ G  GP G
Sbjct: 578 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSP-NSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             G MG  G PGPPG  GNPGP     PQG    + PP +K               LAG+
Sbjct: 638 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGK--------PGLAGL 686

Query: 302 PGPRGPPGPP------------GPPGPRGP---PGPPGTPGSQGLAGERGTVGPSGE--- 343
           PG  GPPG P            GPPGP+GP   PGP G  G+ G+ G +G+ G  GE   
Sbjct: 687 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 746

Query: 344 PGVKGEEGEKAATAE 358
           PG KG+ G K    E
Sbjct: 747 PGFKGDMGLKGDRGE 761



 Score =  115 bits (289), Expect = 6e-26
 Identities = 80/219 (36%), Positives = 100/219 (45%), Gaps = 24/219 (10%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAG--PPGQT--GP 207
           E  ++P+SP N+    E  P    E  + +     H    ++   G      PG    GP
Sbjct: 349 EYEDKPTSPPNE----EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP 404

Query: 208 PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP-------GPAG 260
           PGPAGP G  G  G  G  GP G PG  GPPG  GLPG  G PGPPG         G  G
Sbjct: 405 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 464

Query: 261 NPGPSPNSP--------QGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           + GP+ ++         Q A  +L+ P     G +     +     +G  G  G PGP G
Sbjct: 465 SKGPTISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSSGAKGESGDPGPQG 523

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           P G +GPPGP G PG +G  G  G  G  GEPG KG+ G
Sbjct: 524 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 562



 Score =  112 bits (281), Expect = 5e-25
 Identities = 79/206 (38%), Positives = 94/206 (45%), Gaps = 33/206 (16%)

Query: 184 PLAHPVPRQ-------RRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG------EKGPAG 230
           P+ +P PR        R   G  G  G+ G PG  G  G KGDRG+ G      E GP G
Sbjct: 716 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 775

Query: 231 PPGLLGP---PGPRGLPGEMGR---------PGPPGPPGPAGNPG-PSPNSPQGAL-YSL 276
           P G  GP   PGP G  GE G+         PG  GP G  G PG P  N  +GA   + 
Sbjct: 776 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 835

Query: 277 QPPTDKDNGDSRLASAIVDTVLAGVPGPR------GPPGPPGPPGPRGPPGPPGTPGSQG 330
           +P      G +    +       G PGP+      GPPGPPG  GP+GP GP G PG +G
Sbjct: 836 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 895

Query: 331 LAGERGTVGPSGEPGVKGEEGEKAAT 356
             G  G  G  G PG +GE G +  T
Sbjct: 896 PPGPPGKDGLPGHPGQRGETGFQGKT 921



 Score =  100 bits (250), Expect = 2e-21
 Identities = 73/165 (44%), Positives = 76/165 (46%), Gaps = 43/165 (26%)

Query: 184  PLAHPVPRQRR----PTGPAGPPG---QTGPPGPAGPPGS---KGDRGQTGEKGPAGPPG 233
            P   P P   R    P G  G PG   Q GPPGP GPPG    KGD G  GEKG  G  G
Sbjct: 1361 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1420

Query: 234  LLGPPGP------RGLPGEMGRPGP------PGPPGPAGNPGP----SPNSPQGALYSLQ 277
            L+GPPG       RGLPG  G PG       PGP GP G PGP     P  P+G   S  
Sbjct: 1421 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG 1480

Query: 278  PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP 322
            P   K  GDS            G+PGP   PG PGPPG    P P
Sbjct: 1481 PAGQK--GDS------------GLPGP---PGSPGPPGEVIQPLP 1508



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 38/98 (38%), Positives = 47/98 (47%), Gaps = 16/98 (16%)

Query: 155  ERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            E+    D  LP  + +P    +  +P                GPAGP G  GPPG  GP 
Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIP----------------GPAGPLGPPGPPGLPGPQ 1470

Query: 215  GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP 252
            G KG++G TG  G  G  GL GPPG  G PGE+ +P P
Sbjct: 1471 GPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 65/204 (31%), Positives = 71/204 (34%), Gaps = 83/204 (40%)

Query: 194 RPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
           +PT P  P  + GP  PA       S    G  GEKG  G P ++ P    G+  E    
Sbjct: 353 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVE---- 402

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGP GPAG  GP           LQ PT                   G PG  G  GP
Sbjct: 403 GPPGPAGPAGIMGPP---------GLQGPT-------------------GPPGDPGDRGP 434

Query: 311 PGP---PGPRGPPGPPGT---------------------------------------PGS 328
           PG    PG  G PGPPGT                                       PG 
Sbjct: 435 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 494

Query: 329 QGLAGERGTVGPSGEPGVKGEEGE 352
            GL G  G VG  G  G KGE G+
Sbjct: 495 MGLTGRPGPVGGPGSSGAKGESGD 518



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 183  IPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
            +P     P  +   G  GP G  GPPGP G PG +G +G  G  GPAG  G  G PGP  
Sbjct: 1436 LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP-- 1493

Query: 243  LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDN 284
                   PG PGPPG    P P  +S +   ++     D D+
Sbjct: 1494 -------PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADD 1528


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  140 bits (352), Expect = 3e-33
 Identities = 78/171 (45%), Positives = 87/171 (50%), Gaps = 29/171 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GPAG PG+ G  G  G PG KG +G  GE GP GPPGL GP G  G+ G  G PGP G
Sbjct: 1115 PAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG 1174

Query: 255  PPGPAGNPG-------PSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG 306
              G  G  G       P P  P G      PP +K +NGD                GP G
Sbjct: 1175 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDV---------------GPMG 1219

Query: 307  PPGPPGPPGPR------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PPGPPGP GP+      GP GPPG+ GS G  GE+G  G +G PG  GE G
Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270



 Score =  138 bits (348), Expect = 9e-33
 Identities = 74/161 (45%), Positives = 82/161 (50%), Gaps = 22/161 (13%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE---MGRPGP- 252
            G  G PG+ G PGP G  G  G +G+ GEKG AGPPG  GPPG +G PG+    G PGP 
Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311

Query: 253  --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              PG PGP G PGP+     G           D G+        D    G PGP G  GP
Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGG----------DKGEDG------DPGQPGPPGPSGEAGP 1355

Query: 311  PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            PGPPG RGPPG  G  G QG  G +G  G  G PG  G  G
Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG 1396



 Score =  138 bits (348), Expect = 9e-33
 Identities = 85/212 (40%), Positives = 102/212 (48%), Gaps = 42/212 (19%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEK---------------GPAGPPGL 234
            P Q  P GP+G  G  GPPG  GPPG+ G  G+ GEK               GP GP G 
Sbjct: 1341 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1400

Query: 235  LGPPGP------------RGLPGEMGRPGPPGPPGPAGNPG--PSPNSP-----QGALYS 275
             G PGP            +GLPG  G+ GPPGP GP G PG    P S       G +  
Sbjct: 1401 AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGL 1460

Query: 276  LQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGE 334
            + PP ++ + GD  L          G PG +G  G PGP GP GPPGPPG PG QG  G 
Sbjct: 1461 IGPPGEQGEKGDRGLPGT------QGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514

Query: 335  RGTVGPSGEPGVKGEEGEKAATA-EGEGVQQL 365
            +G+ GP+G+ G  G  G   +    GE +Q L
Sbjct: 1515 KGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL 1546



 Score =  137 bits (344), Expect = 3e-32
 Identities = 74/161 (45%), Positives = 87/161 (54%), Gaps = 22/161 (13%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GP G TG PGP G PGS G +G++G+ GP GP G+ GPPGP G PG+ GRPG  G  
Sbjct: 529 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 588

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G PG   +     L  L  P DK +   R              GP+GPPGPPG  G 
Sbjct: 589 GMPGEPGAKGDRGFDGLPGL--PGDKGHRGER--------------GPQGPPGPPGDDGM 632

Query: 317 R------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           R      GP G PG  G +GL G RGT G  G+PG+ G +G
Sbjct: 633 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDG 673



 Score =  137 bits (344), Expect = 3e-32
 Identities = 81/188 (43%), Positives = 95/188 (50%), Gaps = 27/188 (14%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGS------KGDRGQT---GEKGPAGPPGLLGPPGP 240
            P +R P GP GP G  GP GP GPPG        G RG+T   G+ GP GP G++GP GP
Sbjct: 915  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974

Query: 241  RGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G  G +G  G PGPPGP G  G P     +GA          D G   ++       L 
Sbjct: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGA--------KGDPGPQGISGKDGPAGLR 1026

Query: 300  GVPGPRGPPGPPGPP------GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVK---GEE 350
            G PG RG PG  G P      GP+GPPGP G+PG +G AG  G +G  G PG +   G  
Sbjct: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPA 1086

Query: 351  GEKAATAE 358
            GEK A  E
Sbjct: 1087 GEKGAPGE 1094



 Score =  136 bits (343), Expect = 3e-32
 Identities = 77/170 (45%), Positives = 88/170 (51%), Gaps = 31/170 (18%)

Query: 192  QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP- 250
            +R   GP GPPG+ G PG AG  G+KGD G  G  G  GP GL G PG RGLPG  G P 
Sbjct: 983  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPG 1042

Query: 251  -----GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
                 GP GPPGP G+PG                   + G +  A  I    L G PGP+
Sbjct: 1043 LKGGEGPQGPPGPVGSPG-------------------ERGSAGTAGPI---GLPGRPGPQ 1080

Query: 306  GPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            GPPGP    G PG +GP GP G  G QG  G  G  GP+G PG  G++GE
Sbjct: 1081 GPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130



 Score =  134 bits (338), Expect = 1e-31
 Identities = 78/180 (43%), Positives = 89/180 (49%), Gaps = 18/180 (10%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG--------- 245
            P G  G  G+ GPPG AGPPG+KG  G  G KG  GP G  G PGP G PG         
Sbjct: 1274 PKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1333

Query: 246  ---EMGRPGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
               E G PG PGPPGP+G  G    P    P GA  +     +K  G    A A      
Sbjct: 1334 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEK--GAKGEAGAEGPPGK 1391

Query: 299  AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
             G  GP+GP G PGP G RG PGP G  G  G AG+ G  GP G PG+ G +G+  +  E
Sbjct: 1392 TGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE 1451



 Score =  134 bits (336), Expect = 2e-31
 Identities = 79/185 (42%), Positives = 95/185 (51%), Gaps = 35/185 (18%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP------AGPPGLLGPPGPRGLPGEMGRP 250
           G  G  G+ GP GP GPPG  G RG+ GE GP      AGP GLLGP G  G PG+ G  
Sbjct: 610 GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           G  GPPGP GN G     PQG      PP  + N   +           G+PGP+GP GP
Sbjct: 670 GVDGPPGPKGNMG-----PQG---EPGPPGQQGNPGPQ-----------GLPGPQGPIGP 710

Query: 311 PGPPGPRGPP---------GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
           PG  GP+G P         GPPG PG +G +GE+G +GP G  G  G  G +      +G
Sbjct: 711 PGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG-ADG 769

Query: 362 VQQLR 366
           V+ L+
Sbjct: 770 VRGLK 774



 Score =  134 bits (336), Expect = 2e-31
 Identities = 87/215 (40%), Positives = 92/215 (42%), Gaps = 51/215 (23%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPP---------GLLGPPGP 240
            P +R   G AGP G  G PGP GPPG  G++G  GEKGP GP          GL GP GP
Sbjct: 1059 PGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGP 1118

Query: 241  RGLPGE------------------MGRPGPPGPP---GPAGNPG-------PSPNSPQGA 272
             G PGE                   G  GPPGPP   GP G PG       P P   QG 
Sbjct: 1119 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1178

Query: 273  LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---------GPPGPPGPPGPRGPPGPP 323
                      D G            L G+PGP          GP GPPGPPGPRGP GP 
Sbjct: 1179 F-----GQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPN 1233

Query: 324  GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
            G  G QG  G  G+VG  GE G  GE G      E
Sbjct: 1234 GADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGE 1268



 Score =  132 bits (331), Expect = 8e-31
 Identities = 76/174 (43%), Positives = 87/174 (50%), Gaps = 13/174 (7%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP---------G 245
           P G  GPPGQ G PGP G PG +G  G  GEKGP G PGL G PG  G P         G
Sbjct: 683 PQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSG 742

Query: 246 EMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL---AGVP 302
           E G  GPPGP GP G PGP        +  L+  +  + G+        D  L    G  
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLK-GSKGEKGEDGFPGFKGDMGLKGDRGEV 801

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAAT 356
           G  GP G  GP GP+G  GP G PG  G AGE+G +G  G PG  G +G K +T
Sbjct: 802 GQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGST 855



 Score =  131 bits (329), Expect = 1e-30
 Identities = 71/156 (45%), Positives = 79/156 (50%), Gaps = 7/156 (4%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G AG PG  G  GP GP GS+G RG TG+ GP G  G  GPPGP G  G  G  GP G P
Sbjct: 871  GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 930

Query: 257  GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
            GP G PGP             P      G++            GV GP+GP G  GP G 
Sbjct: 931  GPKGPPGPPGKDG-------LPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGE 983

Query: 317  RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            RG PGPPG PG QGL G  G  G  G+PG +G  G+
Sbjct: 984  RGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019



 Score =  128 bits (321), Expect = 1e-29
 Identities = 75/182 (41%), Positives = 84/182 (46%), Gaps = 27/182 (14%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGP---PGPRGLPGEMGRPG 251
            P G  G  G  GP GP GPPG +G +G  G  GP GPPG +G     G +G PGE G PG
Sbjct: 1205 PPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPG 1264

Query: 252  PP------------------GPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRL 289
            PP                  GPPG AG PG    P  + P+G    +  P D   G    
Sbjct: 1265 PPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGE 1322

Query: 290  ASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
                    + G  G  G PG PGPPGP G  GPPG PG +G  G  G  G  GE G KGE
Sbjct: 1323 PGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382

Query: 350  EG 351
             G
Sbjct: 1383 AG 1384



 Score =  125 bits (314), Expect = 8e-29
 Identities = 69/160 (43%), Positives = 82/160 (51%), Gaps = 18/160 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG  G PG AG  G  G +G  G +G  GPPG  G PGP+GLPG  G  GPPG  
Sbjct: 655 GPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEK 714

Query: 257 GPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           GP G PG    P  + P G      P  +  +G+             G PGP+GP G PG
Sbjct: 715 GPQGKPGLAGLPGADGPPG-----HPGKEGQSGEKG---------ALGPPGPQGPIGYPG 760

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           P G +G  G  G  GS+G  GE G  G  G+ G+KG+ GE
Sbjct: 761 PRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGE 800



 Score =  125 bits (314), Expect = 8e-29
 Identities = 79/183 (43%), Positives = 86/183 (46%), Gaps = 31/183 (16%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G  G  GP G AGP G  G  GQ GEKG  G PGL G PG +G  G  G PG PG  
Sbjct: 805 GPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGAN 864

Query: 257 GP------AGNPGP----SPNSPQGALYSLQP-----PTDKDNGDSRLASAIVDTVLAGV 301
           G       AG PGP     P  P+G+  +  P     P     GD             G 
Sbjct: 865 GEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP----------PGP 914

Query: 302 PGPRGPPGPPGP---PGPRGPPGPP---GTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           PG RGP GP GP   PGP+GPPGPP   G PG  G  GE G  G +G PG  G  G +  
Sbjct: 915 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974

Query: 356 TAE 358
           T E
Sbjct: 975 TGE 977



 Score =  125 bits (314), Expect = 8e-29
 Identities = 73/176 (41%), Positives = 86/176 (48%), Gaps = 27/176 (15%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P +R   G  G PG  G  GP GPP   GS G+RG  G  GP G PG  GP GP G  GE
Sbjct: 1029 PGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGE 1088

Query: 247  MGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G PG  GP GPAG  G       P P  P G+     P  D D G+             
Sbjct: 1089 KGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS-----PGEDGDKGE------------I 1131

Query: 300  GVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            G PG +G  G  G  GP GPPG  G  G+ G+AG  G  GP G+ G+ G++G++ A
Sbjct: 1132 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187



 Score =  125 bits (313), Expect = 1e-28
 Identities = 81/195 (41%), Positives = 94/195 (48%), Gaps = 39/195 (20%)

Query: 192 QRRPTGPAGPP------GQTGPPGPAGPPGSKGDRGQTGEK---GPAGPPGLLGPPGPRG 242
           +R P GP GPP      G+ G  GP G PG  G RG  G +   G  G PG+ G  GP G
Sbjct: 617 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSP-NSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
             G MG  G PGPPG  GNPGP     PQG    + PP +K               LAG+
Sbjct: 677 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGK--------PGLAGL 725

Query: 302 PGPRGPPGPP------------GPPGPRGP---PGPPGTPGSQGLAGERGTVGPSGE--- 343
           PG  GPPG P            GPPGP+GP   PGP G  G+ G+ G +G+ G  GE   
Sbjct: 726 PGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF 785

Query: 344 PGVKGEEGEKAATAE 358
           PG KG+ G K    E
Sbjct: 786 PGFKGDMGLKGDRGE 800



 Score =  115 bits (289), Expect = 6e-26
 Identities = 80/219 (36%), Positives = 100/219 (45%), Gaps = 24/219 (10%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAG--PPGQT--GP 207
           E  ++P+SP N+    E  P    E  + +     H    ++   G      PG    GP
Sbjct: 388 EYEDKPTSPPNE----EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGP 443

Query: 208 PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP-------GPAG 260
           PGPAGP G  G  G  G  GP G PG  GPPG  GLPG  G PGPPG         G  G
Sbjct: 444 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 503

Query: 261 NPGPSPNSP--------QGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           + GP+ ++         Q A  +L+ P     G +     +     +G  G  G PGP G
Sbjct: 504 SKGPTISAQEAQAQAILQQARIALRGPPG-PMGLTGRPGPVGGPGSSGAKGESGDPGPQG 562

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           P G +GPPGP G PG +G  G  G  G  GEPG KG+ G
Sbjct: 563 PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRG 601



 Score =  112 bits (281), Expect = 5e-25
 Identities = 79/206 (38%), Positives = 94/206 (45%), Gaps = 33/206 (16%)

Query: 184 PLAHPVPRQ-------RRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG------EKGPAG 230
           P+ +P PR        R   G  G  G+ G PG  G  G KGDRG+ G      E GP G
Sbjct: 755 PIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG 814

Query: 231 PPGLLGP---PGPRGLPGEMGR---------PGPPGPPGPAGNPG-PSPNSPQGAL-YSL 276
           P G  GP   PGP G  GE G+         PG  GP G  G PG P  N  +GA   + 
Sbjct: 815 PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAG 874

Query: 277 QPPTDKDNGDSRLASAIVDTVLAGVPGPR------GPPGPPGPPGPRGPPGPPGTPGSQG 330
           +P      G +    +       G PGP+      GPPGPPG  GP+GP GP G PG +G
Sbjct: 875 KPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKG 934

Query: 331 LAGERGTVGPSGEPGVKGEEGEKAAT 356
             G  G  G  G PG +GE G +  T
Sbjct: 935 PPGPPGKDGLPGHPGQRGETGFQGKT 960



 Score =  100 bits (250), Expect = 2e-21
 Identities = 73/165 (44%), Positives = 76/165 (46%), Gaps = 43/165 (26%)

Query: 184  PLAHPVPRQRR----PTGPAGPPG---QTGPPGPAGPPGS---KGDRGQTGEKGPAGPPG 233
            P   P P   R    P G  G PG   Q GPPGP GPPG    KGD G  GEKG  G  G
Sbjct: 1400 PAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIG 1459

Query: 234  LLGPPGP------RGLPGEMGRPGP------PGPPGPAGNPGP----SPNSPQGALYSLQ 277
            L+GPPG       RGLPG  G PG       PGP GP G PGP     P  P+G   S  
Sbjct: 1460 LIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTG 1519

Query: 278  PPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGP 322
            P   K  GDS            G+PGP   PG PGPPG    P P
Sbjct: 1520 PAGQK--GDS------------GLPGP---PGSPGPPGEVIQPLP 1547



 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 38/98 (38%), Positives = 47/98 (47%), Gaps = 16/98 (16%)

Query: 155  ERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            E+    D  LP  + +P    +  +P                GPAGP G  GPPG  GP 
Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIP----------------GPAGPLGPPGPPGLPGPQ 1509

Query: 215  GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP 252
            G KG++G TG  G  G  GL GPPG  G PGE+ +P P
Sbjct: 1510 GPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 65/204 (31%), Positives = 71/204 (34%), Gaps = 83/204 (40%)

Query: 194 RPTGPAGPPGQTGPPGPAGPP---GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP 250
           +PT P  P  + GP  PA       S    G  GEKG  G P ++ P    G+  E    
Sbjct: 392 KPTSP--PNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVE---- 441

Query: 251 GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
           GPPGP GPAG  GP           LQ PT                   G PG  G  GP
Sbjct: 442 GPPGPAGPAGIMGPP---------GLQGPT-------------------GPPGDPGDRGP 473

Query: 311 PGP---PGPRGPPGPPGT---------------------------------------PGS 328
           PG    PG  G PGPPGT                                       PG 
Sbjct: 474 PGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGP 533

Query: 329 QGLAGERGTVGPSGEPGVKGEEGE 352
            GL G  G VG  G  G KGE G+
Sbjct: 534 MGLTGRPGPVGGPGSSGAKGESGD 557



 Score = 66.6 bits (161), Expect = 4e-11
 Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 9/102 (8%)

Query: 183  IPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
            +P     P  +   G  GP G  GPPGP G PG +G +G  G  GPAG  G  G PGP  
Sbjct: 1475 LPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP-- 1532

Query: 243  LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDN 284
                   PG PGPPG    P P  +S +   ++     D D+
Sbjct: 1533 -------PGSPGPPGEVIQPLPILSSKKTRRHTEGMQADADD 1567


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score =  140 bits (352), Expect = 3e-33
 Identities = 87/215 (40%), Positives = 103/215 (47%), Gaps = 42/215 (19%)

Query: 200 GPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP--- 256
           GPPG+ GPPGP GPPG  G  G  G++GP GPP   GPPGP G PG+ G PG PG P   
Sbjct: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP---GPPGPAGEPGKPGAPGKPGTPGAD 82

Query: 257 ---GPAGNPG----------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
              GP G+PG          P     +G      P      G + L   +      G PG
Sbjct: 83  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPG 142

Query: 304 PRGPPGPPGPPGPRG---------------PPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
            RGPPGPPGPPGPRG               PPG  G PG  G+ G +G  G  GEPG +G
Sbjct: 143 RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 202

Query: 349 EEGEKAATAE-GE-------GVQQLREALKILAER 375
            +GE+    E GE       G Q LR    I+ ++
Sbjct: 203 HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 237



 Score =  126 bits (316), Expect = 4e-29
 Identities = 71/169 (42%), Positives = 91/169 (53%), Gaps = 10/169 (5%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG---EKGPAGPPGLLGPPGPRGLPGE 246
           P ++   G  G  G+ G  G  GPPG++G RG TG   +KG  G  GL G PGP+GLPG 
Sbjct: 198 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257

Query: 247 MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
            G  G  GPPG AG  G         +  L  P     GD+ L        + G+PG +G
Sbjct: 258 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP----KGDTGLPGVDGRDGIPGMPGTKG 313

Query: 307 PPGPPGPPGP---RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            PG PGPPG    +G PG PG PG++G+AGE+G+ G  G+PG  G  G+
Sbjct: 314 EPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 362



 Score =  125 bits (313), Expect = 1e-28
 Identities = 79/204 (38%), Positives = 97/204 (47%), Gaps = 20/204 (9%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G +G PGQ GPPG  GP G +G  G  GE GP G PGL G  G  G PG  G PGPPG P
Sbjct: 358 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417

Query: 257 GPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           G  G+ G    P P   QGA          + G++     + D    G+PGP+G  G PG
Sbjct: 418 GMKGDRGVVGEPGPKGEQGA--------SGEEGEAGERGELGD---IGLPGPKGSAGNPG 466

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQQLREALKIL 372
            PG RGP G  G PG +G  G  G  G  GE G  G  G +         Q +++    +
Sbjct: 467 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQ----V 522

Query: 373 AERVLILEHMIGIHDPLASPEGGS 396
             RV I EH   +   L  P+ G+
Sbjct: 523 CMRV-IQEHFAEMAASLKRPDSGA 545



 Score =  122 bits (307), Expect = 5e-28
 Identities = 70/155 (45%), Positives = 77/155 (49%), Gaps = 4/155 (2%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP G PG  G  G  GPPG  G +G  G +G  G PGL GP G  GLPG  GR G PG P
Sbjct: 250 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G PG  P  P  A     P      G   +A     T   G PG  G  G  G PG 
Sbjct: 310 GTKGEPG-KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST---GAPGKPGQMGNSGKPGQ 365

Query: 317 RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           +GPPG  G  G QGL G RG +GP G PG+ G+ G
Sbjct: 366 QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLG 400



 Score =  121 bits (304), Expect = 1e-27
 Identities = 76/207 (36%), Positives = 87/207 (42%), Gaps = 44/207 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  G PG  G PGP G PG KGDRG  GE GP G  G  G  G  G  GE+G  G PGP 
Sbjct: 400 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 459

Query: 257 GPAGNPG----------------------PSPNSPQG-----ALYSLQPPTDKDNGDSRL 289
           G AGNPG                      P P   QG      L  +Q P  +   D  +
Sbjct: 460 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 519

Query: 290 ASAIV-----------------DTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA 332
               +                 D+   G+PG  GPPGPPGPPG  G PG  G  G  G+ 
Sbjct: 520 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 579

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEG 359
           G  G +G  G  G  GE+GE+     G
Sbjct: 580 GPPGALGLRGPKGDLGEKGERGPPGRG 606



 Score =  111 bits (278), Expect = 1e-24
 Identities = 79/195 (40%), Positives = 86/195 (44%), Gaps = 16/195 (8%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGP------------PGQTGPPGPAGPPGSKGDRGQTGEKG 227
           P  +P A     QR P G AGP            PG  GP G  G PG  G  G  G  G
Sbjct: 251 PQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPG 310

Query: 228 PAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGP--SPNSPQGALYSLQPPTDKDNG 285
             G PG  GPPG  GL G  G PG PG  G AG  G   +P  P     S +P      G
Sbjct: 311 TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 370

Query: 286 DSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPG 345
           +             G  GP G PG PG  G  G PG PG PG  GL G +G  G  GEPG
Sbjct: 371 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 430

Query: 346 VKGEEGEKAATAEGE 360
            KGE+G  A+  EGE
Sbjct: 431 PKGEQG--ASGEEGE 443



 Score =  106 bits (264), Expect = 5e-23
 Identities = 84/230 (36%), Positives = 90/230 (39%), Gaps = 70/230 (30%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA 211
           EA ER    D  LP P+ +     E             P  R P G  G PG  GP GP 
Sbjct: 443 EAGERGELGDIGLPGPKGSAGNPGE-------------PGLRGPEGSRGLPGVEGPRGPP 489

Query: 212 GPPGSKGDRGQTGEKGPAGPPG--------------------------LLGPP-GPRGLP 244
           GP G +G++G TG  G  GPPG                          L  P  G  GLP
Sbjct: 490 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 549

Query: 245 GEMGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTD---------KDNGDSR 288
           G  G PGPPGPPG  G PG       P    P GAL    P  D            G + 
Sbjct: 550 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNG 609

Query: 289 LASAIVDTVLAGVPGP-----------RGPPGPPGPPGPRGPPGPPGTPG 327
           L  AI    L G PGP           RGPPG  G PG  GPPGPPG PG
Sbjct: 610 LPGAIG---LPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 37/102 (36%), Positives = 40/102 (39%), Gaps = 25/102 (24%)

Query: 168 ESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPP--GQTGPPGPAGPPGSKGDRGQTGE 225
           E  PP    + LP AI L           G  GP   G+ G  G  GPP           
Sbjct: 599 ERGPPGRGPNGLPGAIGLP----------GDPGPASYGRNGRDGERGPP----------- 637

Query: 226 KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGP-AGNPGPSP 266
            G AG PG+ GPPGP GLPG           G  A N GP P
Sbjct: 638 -GVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678


>gi|38570075 collagen, type XXV, alpha 1 isoform 1 [Homo sapiens]
          Length = 654

 Score =  140 bits (352), Expect = 3e-33
 Identities = 84/208 (40%), Positives = 101/208 (48%), Gaps = 44/208 (21%)

Query: 184 PLAHPVPRQRRPT-GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP-------------- 228
           P   P  R +R   G +GPPGQ   PGP GPPG KGD+G+ G++GP              
Sbjct: 121 PAGPPGKRGKRGRRGESGPPGQ---PGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSA 177

Query: 229 ----------------AGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGA 272
                           AGPPG  GPPGPRG PG+ G+ GP G PG  G PG      QG 
Sbjct: 178 DQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKP--GEQGL 235

Query: 273 LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA 332
           +  L PP  K         +I    + G+ G +G PG PG  G  G PGP G PG QG  
Sbjct: 236 MGPLGPPGQK--------GSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEK 287

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G+ G  GP G+ G KG+ G  AA  +GE
Sbjct: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGE 315



 Score =  130 bits (328), Expect = 2e-30
 Identities = 76/182 (41%), Positives = 88/182 (48%), Gaps = 13/182 (7%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           Q  P GP GPPG  GPPG  G  G +G  G  GE G  G  GL+GP GP G  G +G PG
Sbjct: 193 QAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG 252

Query: 252 PPGPPGPAGNPGPSPNSPQGALYSL--QPPTDKDNGDSRLASAIVDTVLAGVPGP----- 304
            PG  G  G PG      Q  +     +P    + GD+       DT   G PG      
Sbjct: 253 IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGI 312

Query: 305 RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV------KGEEGEKAATAE 358
           +G PG  G PG +G PG PG PG  G+ GE G +GP GEPG+      KGE GE      
Sbjct: 313 KGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR 372

Query: 359 GE 360
           GE
Sbjct: 373 GE 374



 Score =  125 bits (313), Expect = 1e-28
 Identities = 77/190 (40%), Positives = 88/190 (46%), Gaps = 51/190 (26%)

Query: 197 GPAGPPGQTGPPG-------------------------PAGPPGSKGDRGQTGEKGPAGP 231
           GP GPPGQ G  G                         P GPPG +G +G  GE+G  G 
Sbjct: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGI 471

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLA 290
           PG+ G  G +G  G+MG PG  G  G  G PG P  N  +G           + GDS   
Sbjct: 472 PGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG-----------EKGDS--- 517

Query: 291 SAIVDTVLAGVPGPRGPP--GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
                    G+PGP+GP   GPPGPPGP GPPGP G  G  G  G  G +GP G  G KG
Sbjct: 518 ---------GMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKG 568

Query: 349 EEGEKAATAE 358
           E GEK A  E
Sbjct: 569 ERGEKGAMGE 578



 Score =  115 bits (288), Expect = 8e-26
 Identities = 78/195 (40%), Positives = 94/195 (48%), Gaps = 29/195 (14%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP-----RGLPGE 246
           Q+   G  G  GQ G PGP G PG +G++G  GE GP G  G  G PG      +G PGE
Sbjct: 259 QKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGE 318

Query: 247 MGRPGPPGPPGPAGNPG-------PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTV 297
            GRPG  G PG  G PG       P    PQG   L  L P T  + G+           
Sbjct: 319 SGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGL-PGTKGERGE----------- 366

Query: 298 LAGVPG--PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            AG PG   RG PG PGP G +G  G  G  GS+G  GE+G  G  G  G  G++G++ A
Sbjct: 367 -AGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGA 425

Query: 356 TAEGEGVQQLREALK 370
           T   +    L EAL+
Sbjct: 426 TEIIDYNGNLHEALQ 440



 Score =  115 bits (288), Expect = 8e-26
 Identities = 76/183 (41%), Positives = 83/183 (45%), Gaps = 32/183 (17%)

Query: 195 PTGPAGPPGQTGPPGPAGPPG---------------SKGDRGQTGEKGPAGPPGLLGPPG 239
           P GP GP G  GP G  G PG                 GD G TGEKG  G PGL G  G
Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANG 509

Query: 240 PRGLPGEMGRPGPPGPP--GPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
            +G  G+ G PGP GP   GP G PGP  P  P G  + L  P   D        A    
Sbjct: 510 MKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP-HGLPGPKGTDGPMGPHGPA---- 564

Query: 297 VLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGL------AGERGTVGPSGEPGVKGEE 350
              G  G RG  G  G PGPRGP G PG  G  GL       GE+G +G  GE G +G +
Sbjct: 565 ---GPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDLGEKGEKGFRGVK 621

Query: 351 GEK 353
           GEK
Sbjct: 622 GEK 624



 Score =  114 bits (285), Expect = 2e-25
 Identities = 80/233 (34%), Positives = 96/233 (41%), Gaps = 67/233 (28%)

Query: 165 PAPESTPPTWNEDF---LPDAIPLAHPVPRQRRPTGPAGPPGQTGP-------------- 207
           P P   P    +D    +P  +P     P ++   GP GPPGQ G               
Sbjct: 203 PGPRGPPGDTGKDGPRGMP-GVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKG 261

Query: 208 -------------PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP-----RGLPGEMGR 249
                        PGP G PG +G++G  GE GP G  G  G PG      +G PGE GR
Sbjct: 262 EPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGR 321

Query: 250 PGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           PG  G PG  G PG       P    PQG                       +  L G+P
Sbjct: 322 PGQKGEPGLPGLPGLPGIKGEPGFIGPQG-----------------------EPGLPGLP 358

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           G +G  G  GPPG RG  G PG PG +G  GE GT GP G  G +GE+G+  A
Sbjct: 359 GTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGA 410



 Score =  104 bits (260), Expect = 1e-22
 Identities = 74/201 (36%), Positives = 85/201 (42%), Gaps = 53/201 (26%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG----- 251
           G +G PGQ G PG  G PG  G +G+ G  GP G PGL G PG +G  GE G PG     
Sbjct: 317 GESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERG 376

Query: 252 PPGPPGPAGNPGPS-PNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPG 309
            PG PGP G  G S    P+G+        D+ + GDS            G  GPRGPPG
Sbjct: 377 EPGAPGPKGKQGESGTRGPKGS------KGDRGEKGDS------------GAQGPRGPPG 418

Query: 310 PPG----------------------------PPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
             G                            PPGP GP G  G  G QG  G  G  G  
Sbjct: 419 QKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ 478

Query: 342 GEPGVKGEEGEKAATAEGEGV 362
           G  G KG+ G+   T E  G+
Sbjct: 479 GLKGSKGDMGDPGMTGEKGGI 499



 Score = 94.4 bits (233), Expect = 2e-19
 Identities = 64/155 (41%), Positives = 67/155 (43%), Gaps = 35/155 (22%)

Query: 197 GPAGPP--GQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           GP GP   G  GPPGP GPPG  G  G  G KG  GP G  GP GP+G  GE G  G PG
Sbjct: 521 GPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPG 580

Query: 255 PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP 314
           P GP G PG                 D + G            L G PGPRG  G  G  
Sbjct: 581 PRGPYGLPGK----------------DGEPG------------LDGFPGPRGEKGDLGEK 612

Query: 315 GP---RGPPGPPGTPGSQGLAGERG--TVGPSGEP 344
           G    RG  G  G PG  GL G      +GP G P
Sbjct: 613 GEKGFRGVKGEKGEPGQPGLDGLDAPCQLGPDGLP 647



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 58/149 (38%), Positives = 63/149 (42%), Gaps = 33/149 (22%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
           P   P  H  P    P G  GP G  GP GP GP G KG+R   GEKG  G P   GP G
Sbjct: 530 PPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGER---GEKGAMGEP---GPRG 583

Query: 240 PRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
           P GLPG+ G PG  G PGP G  G                   D G+        +    
Sbjct: 584 PYGLPGKDGEPGLDGFPGPRGEKG-------------------DLGEKG------EKGFR 618

Query: 300 GVPGPRGPPGPPGPPGPRGP--PGPPGTP 326
           GV G +G PG PG  G   P   GP G P
Sbjct: 619 GVKGEKGEPGQPGLDGLDAPCQLGPDGLP 647


>gi|38570073 collagen, type XXV, alpha 1 isoform 2 [Homo sapiens]
          Length = 642

 Score =  140 bits (352), Expect = 3e-33
 Identities = 84/208 (40%), Positives = 101/208 (48%), Gaps = 44/208 (21%)

Query: 184 PLAHPVPRQRRPT-GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP-------------- 228
           P   P  R +R   G +GPPGQ   PGP GPPG KGD+G+ G++GP              
Sbjct: 121 PAGPPGKRGKRGRRGESGPPGQ---PGPQGPPGPKGDKGEQGDQGPRMVFPKINHGFLSA 177

Query: 229 ----------------AGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGA 272
                           AGPPG  GPPGPRG PG+ G+ GP G PG  G PG      QG 
Sbjct: 178 DQQLIKRRLIKGDQGQAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKP--GEQGL 235

Query: 273 LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA 332
           +  L PP  K         +I    + G+ G +G PG PG  G  G PGP G PG QG  
Sbjct: 236 MGPLGPPGQK--------GSIGAPGIPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEK 287

Query: 333 GERGTVGPSGEPGVKGEEGEKAATAEGE 360
           G+ G  GP G+ G KG+ G  AA  +GE
Sbjct: 288 GDAGENGPKGDTGEKGDPGSSAAGIKGE 315



 Score =  130 bits (328), Expect = 2e-30
 Identities = 76/182 (41%), Positives = 88/182 (48%), Gaps = 13/182 (7%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           Q  P GP GPPG  GPPG  G  G +G  G  GE G  G  GL+GP GP G  G +G PG
Sbjct: 193 QAGPPGPPGPPGPRGPPGDTGKDGPRGMPGVPGEPGKPGEQGLMGPLGPPGQKGSIGAPG 252

Query: 252 PPGPPGPAGNPGPSPNSPQGALYSL--QPPTDKDNGDSRLASAIVDTVLAGVPGP----- 304
            PG  G  G PG      Q  +     +P    + GD+       DT   G PG      
Sbjct: 253 IPGMNGQKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGI 312

Query: 305 RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV------KGEEGEKAATAE 358
           +G PG  G PG +G PG PG PG  G+ GE G +GP GEPG+      KGE GE      
Sbjct: 313 KGEPGESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGR 372

Query: 359 GE 360
           GE
Sbjct: 373 GE 374



 Score =  125 bits (313), Expect = 1e-28
 Identities = 77/190 (40%), Positives = 88/190 (46%), Gaps = 51/190 (26%)

Query: 197 GPAGPPGQTGPPG-------------------------PAGPPGSKGDRGQTGEKGPAGP 231
           GP GPPGQ G  G                         P GPPG +G +G  GE+G  G 
Sbjct: 412 GPRGPPGQKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGI 471

Query: 232 PGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLA 290
           PG+ G  G +G  G+MG PG  G  G  G PG P  N  +G           + GDS   
Sbjct: 472 PGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANGMKG-----------EKGDS--- 517

Query: 291 SAIVDTVLAGVPGPRGPP--GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
                    G+PGP+GP   GPPGPPGP GPPGP G  G  G  G  G +GP G  G KG
Sbjct: 518 ---------GMPGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKG 568

Query: 349 EEGEKAATAE 358
           E GEK A  E
Sbjct: 569 ERGEKGAMGE 578



 Score =  115 bits (288), Expect = 8e-26
 Identities = 78/195 (40%), Positives = 94/195 (48%), Gaps = 29/195 (14%)

Query: 192 QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP-----RGLPGE 246
           Q+   G  G  GQ G PGP G PG +G++G  GE GP G  G  G PG      +G PGE
Sbjct: 259 QKGEPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGE 318

Query: 247 MGRPGPPGPPGPAGNPG-------PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTV 297
            GRPG  G PG  G PG       P    PQG   L  L P T  + G+           
Sbjct: 319 SGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGL-PGTKGERGE----------- 366

Query: 298 LAGVPG--PRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            AG PG   RG PG PGP G +G  G  G  GS+G  GE+G  G  G  G  G++G++ A
Sbjct: 367 -AGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQGPRGPPGQKGDQGA 425

Query: 356 TAEGEGVQQLREALK 370
           T   +    L EAL+
Sbjct: 426 TEIIDYNGNLHEALQ 440



 Score =  114 bits (285), Expect = 2e-25
 Identities = 80/233 (34%), Positives = 96/233 (41%), Gaps = 67/233 (28%)

Query: 165 PAPESTPPTWNEDF---LPDAIPLAHPVPRQRRPTGPAGPPGQTGP-------------- 207
           P P   P    +D    +P  +P     P ++   GP GPPGQ G               
Sbjct: 203 PGPRGPPGDTGKDGPRGMP-GVPGEPGKPGEQGLMGPLGPPGQKGSIGAPGIPGMNGQKG 261

Query: 208 -------------PGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP-----RGLPGEMGR 249
                        PGP G PG +G++G  GE GP G  G  G PG      +G PGE GR
Sbjct: 262 EPGLPGAVGQNGIPGPKGEPGEQGEKGDAGENGPKGDTGEKGDPGSSAAGIKGEPGESGR 321

Query: 250 PGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           PG  G PG  G PG       P    PQG                       +  L G+P
Sbjct: 322 PGQKGEPGLPGLPGLPGIKGEPGFIGPQG-----------------------EPGLPGLP 358

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
           G +G  G  GPPG RG  G PG PG +G  GE GT GP G  G +GE+G+  A
Sbjct: 359 GTKGERGEAGPPG-RGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGA 410



 Score =  114 bits (284), Expect = 2e-25
 Identities = 76/189 (40%), Positives = 81/189 (42%), Gaps = 47/189 (24%)

Query: 195 PTGPAGPPGQTGPPGPAGPPG---------------SKGDRGQTGEKGPAGPPGLLGPPG 239
           P GP GP G  GP G  G PG                 GD G TGEKG  G PGL G  G
Sbjct: 450 PPGPPGPQGLQGPKGEQGSPGIPGMDGEQGLKGSKGDMGDPGMTGEKGGIGLPGLPGANG 509

Query: 240 PRGLPGEMGRPGPPGPP--GPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
            +G  G+ G PGP GP   GP G PGP  P  P G  + L  P                 
Sbjct: 510 MKGEKGDSGMPGPQGPSIIGPPGPPGPHGPPGPMGP-HGLPGPK---------------- 552

Query: 297 VLAGVPGPRGPPGPPGPPGPR---------GPPGPPGTPGSQGLAGERGTVGPSGEPGVK 347
              G  GP GP GP GP G R         GP GP G PG  G  G  G  GP GE G  
Sbjct: 553 ---GTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDL 609

Query: 348 GEEGEKAAT 356
           GE+GEK  +
Sbjct: 610 GEKGEKVTS 618



 Score =  104 bits (260), Expect = 1e-22
 Identities = 74/201 (36%), Positives = 85/201 (42%), Gaps = 53/201 (26%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG----- 251
           G +G PGQ G PG  G PG  G +G+ G  GP G PGL G PG +G  GE G PG     
Sbjct: 317 GESGRPGQKGEPGLPGLPGLPGIKGEPGFIGPQGEPGLPGLPGTKGERGEAGPPGRGERG 376

Query: 252 PPGPPGPAGNPGPS-PNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPG 309
            PG PGP G  G S    P+G+        D+ + GDS            G  GPRGPPG
Sbjct: 377 EPGAPGPKGKQGESGTRGPKGS------KGDRGEKGDS------------GAQGPRGPPG 418

Query: 310 PPG----------------------------PPGPRGPPGPPGTPGSQGLAGERGTVGPS 341
             G                            PPGP GP G  G  G QG  G  G  G  
Sbjct: 419 QKGDQGATEIIDYNGNLHEALQRITTLTVTGPPGPPGPQGLQGPKGEQGSPGIPGMDGEQ 478

Query: 342 GEPGVKGEEGEKAATAEGEGV 362
           G  G KG+ G+   T E  G+
Sbjct: 479 GLKGSKGDMGDPGMTGEKGGI 499



 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 45/93 (48%), Positives = 48/93 (51%), Gaps = 10/93 (10%)

Query: 188 PVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEM 247
           P P+     GP GPPG  GPPGP GP G  G +G  G  GP GP    GP G RG  G M
Sbjct: 520 PGPQGPSIIGPPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGP---AGPKGERGEKGAM 576

Query: 248 GRPGPPGP---PGPAGNPG----PSPNSPQGAL 273
           G PGP GP   PG  G PG    P P   +G L
Sbjct: 577 GEPGPRGPYGLPGKDGEPGLDGFPGPRGEKGDL 609



 Score = 77.4 bits (189), Expect = 2e-14
 Identities = 41/90 (45%), Positives = 43/90 (47%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
           P   P  H  P    P G  GP G  GP GP GP G KG+RG+ G  G  GP G  G PG
Sbjct: 530 PPGPPGPHGPPGPMGPHGLPGPKGTDGPMGPHGPAGPKGERGEKGAMGEPGPRGPYGLPG 589

Query: 240 PRGLPGEMGRPGPPGPPGPAGNPGPSPNSP 269
             G PG  G PGP G  G  G  G    SP
Sbjct: 590 KDGEPGLDGFPGPRGEKGDLGEKGEKVTSP 619


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  139 bits (351), Expect = 4e-33
 Identities = 73/158 (46%), Positives = 87/158 (55%), Gaps = 9/158 (5%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            GP GPPG  G  G  G PG +G+ G  G+ GP GP G+LGP G  G  G +G  GPPGPP
Sbjct: 881  GPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940

Query: 257  GPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPG 315
            GP G  G P     +GA   L PP     G    A       L G PGP+G PG PGP G
Sbjct: 941  GPPGEQGLPGLEGREGAKGELGPPGPL--GKEGPAG------LRGFPGPKGGPGDPGPTG 992

Query: 316  PRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             +G  GPPG  G+ G  GERG +GP+G  G+ G+ G +
Sbjct: 993  LKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSE 1030



 Score =  135 bits (340), Expect = 7e-32
 Identities = 81/208 (38%), Positives = 105/208 (50%), Gaps = 26/208 (12%)

Query: 184  PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243
            P A   P +R P+G  G  G+ G  G  G PG  G  G+TG  G  GPPG +GP G RG+
Sbjct: 1303 PGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362

Query: 244  PGEMGRP---------GPPGPPGPAGNPG-PSPNSPQ------GALYSLQPPTDK-DNGD 286
            PG +G P         GPPGP GP+G PG      P+      G +  + PP +  + GD
Sbjct: 1363 PGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGD 1422

Query: 287  SRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTP---GSQGLAGERGTVGPSGE 343
              L        + G PGP+G PGPPGP G  G PGPPG     G +G  G  G++GP G+
Sbjct: 1423 QGLPG------VQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGD 1476

Query: 344  PGVKGEEGEKAATAEGEGVQQLREALKI 371
             G  G  G   A AE  G+++ R  + +
Sbjct: 1477 TGPAGPPGPPGAPAELHGLRRRRRFVPV 1504



 Score =  131 bits (330), Expect = 1e-30
 Identities = 75/171 (43%), Positives = 83/171 (48%), Gaps = 18/171 (10%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP- 253
            P G  GPPG  GPPG  G PG +G  G  GE GP GP G  GP G RG PG  G PG P 
Sbjct: 930  PLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPG 989

Query: 254  --------GPPGPAG-NPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP 304
                    GPPGP G N  P    P G    +  P     G S     +      G  G 
Sbjct: 990  PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLP-----GQSGSEGPVGPAGKKGSRGE 1044

Query: 305  RGPPGPPGP---PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            RGPPGP G    PGP GP GPPG  G  G  G++G VG  G  G KG++G+
Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGD 1095



 Score =  131 bits (330), Expect = 1e-30
 Identities = 74/175 (42%), Positives = 86/175 (49%), Gaps = 21/175 (12%)

Query: 187  HPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            H  P  R P GP G  G  G PG  G PG+ G++G+ G+ G  GPPG  G PGP+G  GE
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230

Query: 247  MGRPGPPGPPGPAGNPGPSPN-------SPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
             G  GP G  GP G  GP           P G    L PP     GD  ++       + 
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPP-----GDPGVSG------ID 1279

Query: 300  GVPGPRGPPGP---PGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            G PG +G PG    PGPPG  G PG PG PG +G +G  G  G  GE G KGE G
Sbjct: 1280 GSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPG 1334



 Score =  128 bits (322), Expect = 9e-30
 Identities = 72/159 (45%), Positives = 83/159 (52%), Gaps = 10/159 (6%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           GP GP G TG PGP G PG  G +G+ G +GP GP GL GP GP G  G+MGRPG  G  
Sbjct: 479 GPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGAR 538

Query: 257 GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP 316
           G  G+ GP  +     L  L  P +K            D    G PGP G  G  G  GP
Sbjct: 539 GLPGDTGPKGDRGFDGLPGL--PGEKGQRG--------DFGHVGQPGPPGEDGERGAEGP 588

Query: 317 RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
            GP G  G PG +GL G RG+ GP+G PGV G +G   A
Sbjct: 589 PGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGA 627



 Score =  127 bits (320), Expect = 2e-29
 Identities = 85/216 (39%), Positives = 97/216 (44%), Gaps = 48/216 (22%)

Query: 186  AHPVPRQRRPTGPAGP---PGQTGPPGPAGPPGSKGDRGQTGEKGPAG------------ 230
            A+  P +R P GPAG    PGQ+G  GP GP G KG RG+ G  GP G            
Sbjct: 1005 ANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064

Query: 231  PPGLLGPPGPRGLPGEMGRPG------------PPGPPG---PAGNPGPSPNSPQGALYS 275
            PPG  GP G  G  G++G PG            PPG PG   PAG+PGP      GA   
Sbjct: 1065 PPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPP--GADGAQGR 1122

Query: 276  LQPP----TDKDNGDSRLASAIVDTVLAGVPGP------------RGPPGPPGPPGPRGP 319
              PP       D+G       I    L G+PGP             GP G PGP GP+GP
Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182

Query: 320  PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAA 355
             G  GTPG  G  G+ G VG  GE G  G+ G   A
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGA 1218



 Score =  127 bits (319), Expect = 2e-29
 Identities = 75/166 (45%), Positives = 84/166 (50%), Gaps = 16/166 (9%)

Query: 195 PTGPAGPPGQTGPPG---PAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP- 250
           P G  G  G+TG PG     GPPGS+G+RGQ G  G  GP G +G  G  G+PGE G P 
Sbjct: 813 PIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPG 872

Query: 251 --GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
             GPPG PGP G PG             +P      G+            AGV GP+G  
Sbjct: 873 LQGPPGFPGPKGPPGHQGKDG-------RPGHPGQRGELGFQGQTGPPGPAGVLGPQGKT 925

Query: 309 GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGE---PGVKGEEG 351
           G  GP G RGPPGPPG PG QGL G  G  G  GE   PG  G+EG
Sbjct: 926 GEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEG 971



 Score =  126 bits (316), Expect = 4e-29
 Identities = 76/178 (42%), Positives = 87/178 (48%), Gaps = 21/178 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGP---PGLLGPPGPRGLPGEMGRPG 251
            P G  G  G +GP G AGPPG KG  G+ G KG  GP   PG LGPPG  G+ G  G PG
Sbjct: 1224 PKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPG 1283

Query: 252  PPGPPGPAGNPGPSPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              G PG  G PGP   S  G   +  PP  +  +G         +    G PGP GPPG 
Sbjct: 1284 EKGDPGDVGGPGPPGAS--GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341

Query: 311  PGPPGPRGPP---------------GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
             GP G RGPP               G PG  G+ G  G  G +GPSG PG+KG+ G K
Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPK 1399



 Score =  123 bits (309), Expect = 3e-28
 Identities = 73/172 (42%), Positives = 85/172 (49%), Gaps = 14/172 (8%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP G  G  G  GP GP G  G  GQ+G +GP GP G  G  G RG PG  G+ G PG
Sbjct: 999  PPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPG 1058

Query: 255  PPGPAGNPGPS-PNSPQGALYSLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPPG 312
            P GP G PG + P+  +G    +  P  K + GD        D    G PG RGP G PG
Sbjct: 1059 PLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG------DAGPPGQPGIRGPAGHPG 1112

Query: 313  PPGP------RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
            PPG       RGPPG  G  G  G+ G  G +GP G  G+ G  GEK    +
Sbjct: 1113 PPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164



 Score =  123 bits (308), Expect = 4e-28
 Identities = 76/184 (41%), Positives = 86/184 (46%), Gaps = 26/184 (14%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P G  G  G  G  GP G PG +G +G TG +G  G PG +G PG  G  GE G  G PG
Sbjct: 1155 PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPG 1214

Query: 255  PPGPAGNPGP-------SPNSPQGALYSLQPPTDK-DNGDSRLASAIVDTVLAGVPGPRG 306
            PPG  G PGP         + P GA     PP  K   G+     ++  T   G+PG  G
Sbjct: 1215 PPGAPGIPGPKGDIGEKGDSGPSGA---AGPPGKKGPPGEDGAKGSVGPT---GLPGDLG 1268

Query: 307  PPGPP------------GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKA 354
            PPG P            G PG  G PGPPG  G  G  G  G  GPSG  G +G EGEK 
Sbjct: 1269 PPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG 1328

Query: 355  ATAE 358
            A  E
Sbjct: 1329 AKGE 1332



 Score =  122 bits (307), Expect = 5e-28
 Identities = 72/167 (43%), Positives = 78/167 (46%), Gaps = 15/167 (8%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLG---------PPGPRGLPG 245
            P G  G PG TG  G  GPPG  G  G  GE+GP GP G +G         P GP G  G
Sbjct: 981  PKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKG 1040

Query: 246  EMGRPGPPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP 304
              G  GPPGP G  G PGP  P  P GA          + GD     A       G  G 
Sbjct: 1041 SRGERGPPGPTGKDGIPGPLGPLGPPGA-----AGPSGEEGDKGDVGAPGHKGSKGDKGD 1095

Query: 305  RGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
             GPPG PG  GP G PGPPG  G+QG  G  G  G  G+ GV+G  G
Sbjct: 1096 AGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142



 Score =  121 bits (304), Expect = 1e-27
 Identities = 80/206 (38%), Positives = 95/206 (46%), Gaps = 35/206 (16%)

Query: 167 PESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEK 226
           P  T P  +  F  D +P    +P ++   G  G  GQ GPPG  G  G++G  G TG+ 
Sbjct: 541 PGDTGPKGDRGF--DGLP---GLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQA 595

Query: 227 GPAGPPGLLGP---PGPRG---------LPGEMGRPGPPGPPGPAGNPG-------PSPN 267
           G  GP GLLGP   PGP G          PG  G  GPPG PGP G  G       P P 
Sbjct: 596 GEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQ 655

Query: 268 SPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPG 327
              G      PP     G+  +        L G  GP G PG  GP G +G  GPPG+ G
Sbjct: 656 GLIGTPGEKGPP-----GNPGIPG------LPGSDGPLGHPGHEGPTGEKGAQGPPGSAG 704

Query: 328 SQGLAGERGTVGPSGEPGVKGEEGEK 353
             G  G RG  G SG  G++GE+GEK
Sbjct: 705 PPGYPGPRGVKGTSGNRGLQGEKGEK 730



 Score =  121 bits (304), Expect = 1e-27
 Identities = 74/175 (42%), Positives = 83/175 (47%), Gaps = 36/175 (20%)

Query: 195 PTGPAGPPGQTG------PPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
           PTG AG PG  G       PGP G PG  G  G  G KG  GPPG  GPPG +G  G  G
Sbjct: 591 PTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQG 650

Query: 249 RPGP------PGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
            PGP      PG  GP GNPG    P  + P G      P  +   G+            
Sbjct: 651 LPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLG-----HPGHEGPTGEK----------- 694

Query: 299 AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
               G +GPPG  GPPG  GP G  GT G++GL GE+G  G  G PG KG+ G K
Sbjct: 695 ----GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLK 745



 Score =  120 bits (301), Expect = 2e-27
 Identities = 72/182 (39%), Positives = 89/182 (48%), Gaps = 27/182 (14%)

Query: 192  QRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG--- 248
            +R P GP GPPG+ G PG  G  G+KG+ G  G  G  GP GL G PGP+G PG+ G   
Sbjct: 933  ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTG 992

Query: 249  ---------------RPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASA 292
                            PG  GP GPAG  G P  +  +G    + P   K +   R    
Sbjct: 993  LKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEG---PVGPAGKKGSRGERGPPG 1049

Query: 293  IVDTVLAGVPGPRGPPGPP---GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
               T   G+PGP GP GPP   GP G  G  G  G PG +G  G++G  GP G+PG++G 
Sbjct: 1050 --PTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP 1107

Query: 350  EG 351
             G
Sbjct: 1108 AG 1109



 Score =  117 bits (293), Expect = 2e-26
 Identities = 86/229 (37%), Positives = 99/229 (43%), Gaps = 26/229 (11%)

Query: 152 EAAERPSSPDNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA 211
           E AE P  P   L  P   P    +   P A          R   G  GP G  G  G  
Sbjct: 505 EGAEGPQGP-RGLQGPHGPPGRVGKMGRPGA-------DGARGLPGDTGPKGDRGFDGLP 556

Query: 212 GPPGSKGDRGQTGEKGPAGPPG------LLGPPGPRGL---PGEMGRPGPPGPPGPAGNP 262
           G PG KG RG  G  G  GPPG        GPPGP G    PG  G  GP G PGP G P
Sbjct: 557 GLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRP 616

Query: 263 GPSP-NSPQGALYSLQPPTDK----DNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPR 317
           G +  +   GA  ++ PP +       G+           L G PG +GPPG PG PG  
Sbjct: 617 GVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLP 676

Query: 318 GPPGPPGTPGSQGLAGERGTVGP---SGEPGVKGEEGEKAATAEGEGVQ 363
           G  GP G PG +G  GE+G  GP   +G PG  G  G K  T+   G+Q
Sbjct: 677 GSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVK-GTSGNRGLQ 724



 Score =  117 bits (293), Expect = 2e-26
 Identities = 73/181 (40%), Positives = 84/181 (46%), Gaps = 18/181 (9%)

Query: 184 PLAHPVPRQRRPTGPAG---PPGQTGPPGPAGPPGSKG---DRGQTGEKGPAGPPGLLGP 237
           PL HP      PTG  G   PPG  GPPG  GP G KG   +RG  GEKG  G  G  G 
Sbjct: 681 PLGHP--GHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGF 738

Query: 238 PGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV 297
            G  GL G+ G+PG PGP G  G  GP   + Q            + G    A       
Sbjct: 739 KGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAG----------EEGPPGSAGEKGKLG 788

Query: 298 LAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
           + G+PG  G PGP G  G  GP GP G  G  G  G+ G  G  G PG +GE G+  AT 
Sbjct: 789 VPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATG 848

Query: 358 E 358
           +
Sbjct: 849 Q 849



 Score =  115 bits (289), Expect = 6e-26
 Identities = 69/189 (36%), Positives = 84/189 (44%), Gaps = 26/189 (13%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR 249
           P  +   G  G  G+ G PGP G  G +G +GQ G+ G  GPPG  G  G  G+PG  G 
Sbjct: 736 PGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGY 795

Query: 250 PGPPGPPGPAGNPGP-------------------SPNSPQGAL-------YSLQPPTDKD 283
           PG PGP G  G PGP                       P G+         + QP    D
Sbjct: 796 PGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGD 855

Query: 284 NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGE 343
            G         +  L G+ GP G PGP GPPG +G  G PG PG +G  G +G  GP G 
Sbjct: 856 VGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGP 915

Query: 344 PGVKGEEGE 352
            GV G +G+
Sbjct: 916 AGVLGPQGK 924



 Score =  115 bits (289), Expect = 6e-26
 Identities = 71/174 (40%), Positives = 80/174 (45%), Gaps = 27/174 (15%)

Query: 197  GPAGPPGQTGPPGPAG------PPGSKGDRGQTGEKGP---AGPPGLLGPPGPRGLPGEM 247
            GP G PG  GPPG  G       PG KGD G  G  GP   +G PG  GPPG RG  G M
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHM 1318

Query: 248  GRPG---------PPGPPGPAGNPGP-SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV 297
            GR G          PGP GP G  GP     P G +           G   +   + +  
Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRV--------GPEGLRGIPGPVGEPG 1370

Query: 298  LAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            L G PG  GPPGP GP G  G  G  G  G +G  G  G +GP GE G KG++G
Sbjct: 1371 LLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424



 Score =  112 bits (281), Expect = 5e-25
 Identities = 75/189 (39%), Positives = 85/189 (44%), Gaps = 37/189 (19%)

Query: 190  PRQRRPTGPAGPPGQTGPPGPAGPPG---SKGDRGQTGEKGPAGPPGLLGPPGP------ 240
            P  R P G  GPPG  G  G  GPPG    KGD G  G  G  GPPGL G PGP      
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161

Query: 241  ---------RGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLAS 291
                            G PGP GP GP G+ G +P  P G     QP    + G+   A 
Sbjct: 1162 VGDVGSMGPH------GAPGPRGPQGPTGSEG-TPGLPGGV---GQPGAVGEKGERGDAG 1211

Query: 292  AIVDTVLAGVPGPR---------GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSG 342
                    G+PGP+         GP G  GPPG +GPPG  G  GS G  G  G +GP G
Sbjct: 1212 DPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPG 1271

Query: 343  EPGVKGEEG 351
            +PGV G +G
Sbjct: 1272 DPGVSGIDG 1280



 Score = 99.8 bits (247), Expect = 4e-21
 Identities = 68/186 (36%), Positives = 79/186 (42%), Gaps = 14/186 (7%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPA-------GPPGSKGDRGQTGEKGPAGPP 232
           PD     +P   Q +    AG  G  G P          GPPG+ G +G  G  GP GPP
Sbjct: 353 PDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPP 412

Query: 233 GLLG---PPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRL 289
           G  G   PPGP GLP   G PG  G  GP G     P    G  +   PP       ++ 
Sbjct: 413 GFPGDPGPPGPAGLP---GIPGIDGIRGPPGTVIMMPFQFAGGSFK-GPPVSFQQAQAQA 468

Query: 290 ASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
                   + G PGP G  G PGP G  G PG  G  G++G  G RG  GP G PG  G+
Sbjct: 469 VLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGK 528

Query: 350 EGEKAA 355
            G   A
Sbjct: 529 MGRPGA 534



 Score = 62.8 bits (151), Expect = 6e-10
 Identities = 31/68 (45%), Positives = 35/68 (51%), Gaps = 3/68 (4%)

Query: 183  IPLAHPVPRQRRPTGPAGPPGQT---GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
            +P     P  +   GP GP G     GPPG AGP G KG +G  G  GP G  G  GPPG
Sbjct: 1425 LPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPG 1484

Query: 240  PRGLPGEM 247
            P G P E+
Sbjct: 1485 PPGAPAEL 1492



 Score = 60.1 bits (144), Expect = 4e-09
 Identities = 61/226 (26%), Positives = 78/226 (34%), Gaps = 59/226 (26%)

Query: 176 EDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKG-------- 227
           E +LPD   LA        P     P G+   P P      KG +   G KG        
Sbjct: 218 ERYLPDCDNLA--------PAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKE 269

Query: 228 ---PAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPA------------------GNPGPSP 266
               + PP          +P +   P P  PP P                    +  P  
Sbjct: 270 IWTSSPPPDSAENQTSTDIP-KTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDS 328

Query: 267 NSPQGALYSLQPPTDKDNGDS------RLASAIVDTVL-----AGVPGPRGPP------- 308
            +  G L +     D++  DS      R A     T       AG  G +G P       
Sbjct: 329 GTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQ 388

Query: 309 ---GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
              GPPG PGP+G  GP G PG  G  G+ G  GP+G PG+ G +G
Sbjct: 389 QFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDG 434


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score =  139 bits (349), Expect = 7e-33
 Identities = 84/193 (43%), Positives = 95/193 (49%), Gaps = 22/193 (11%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQ---------TGEKGPAG 230
           P  IP  +    +R   G  G PG  GPPGP G PG KG+ G           G  G  G
Sbjct: 118 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177

Query: 231 PPGLLGPPGPRGLPGEMGRPGPP---GPPGPAGNPGPSPN------SPQG--ALYSLQPP 279
           PPG+ G PGP G+PG +G PGPP   GPPGP G PGP  N       P+G      LQ P
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  S     I      G  G  G  GPPGPPG RGPPGPPG  G +G  GE+G  G
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPG 295

Query: 340 PSGEPGVKGEEGE 352
             G+PG  GE G+
Sbjct: 296 KRGKPGKDGENGQ 308



 Score =  135 bits (339), Expect = 1e-31
 Identities = 85/224 (37%), Positives = 101/224 (45%), Gaps = 47/224 (20%)

Query: 165 PAPESTP-PTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGP------PGSK 217
           P P   P P     F     P    +P  +   GP G  G  GPPGP G       PG K
Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK 798

Query: 218 GDRGQTGEKGPAGPPGL-----LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGA 272
           GD G  G+ GP GPPGL      GPPGP G+PG +G+PG  G PG  G+PGP      G 
Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG- 857

Query: 273 LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP------------------ 314
                PP ++ +             + G PGP GPPG PG P                  
Sbjct: 858 -----PPGERGSPG-----------IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 315 GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           GP GPPGP G PG  G+ G +G  G  G+PG+ G  GEK +  E
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945



 Score =  132 bits (333), Expect = 5e-31
 Identities = 74/174 (42%), Positives = 89/174 (51%), Gaps = 14/174 (8%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP--- 253
           G  G PG  G PGP GPPG +G +G  G  GP GP G+ GPPG  G PG  G PG P   
Sbjct: 54  GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 254 GPPGPAGNPGPS--------PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
           G PGP G PG +        P SP      LQ P     G   +       +++ +PGP+
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSP--GFPGLQGPPGPP-GIPGMKGEPGSIIMSSLPGPK 170

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           G PG PGPPG +G PGP G PG  G  G  G +GP G PG+ G +G      +G
Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQG 224



 Score =  132 bits (331), Expect = 8e-31
 Identities = 76/181 (41%), Positives = 91/181 (50%), Gaps = 32/181 (17%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P +  P G  G PGQ GPPG  G PG  G  G  G+KG  G PG  G PGP GLPG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSG 1202

Query: 249  R---------PGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            +         PG PG PGP G PG    P    P G   S  P  +   G+         
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN--------- 1253

Query: 296  TVLAGVPGPRGPPGPPGPPGPR---GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
                  PGP+GPPG PGP G +   GP GPPG PG+ G+ GE+G  G  G PG+ G +G+
Sbjct: 1254 ------PGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGD 1307

Query: 353  K 353
            +
Sbjct: 1308 Q 1308



 Score =  130 bits (326), Expect = 3e-30
 Identities = 75/171 (43%), Positives = 88/171 (51%), Gaps = 20/171 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP G PG  G PG  GPPG KG     G+ G  GP G+ GPPGP G+PG+ G PG PG
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGT---IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 255  PPGPAGNPG------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
              G  G+PG      P    P+G     +P      G+  +  ++ D  L G+PG  G  
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKG-----EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 309  GPPGPPGPRGPPGPP------GTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG  G PGPP      G PG+ GL GE G VG  G PG  G  GEK
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166



 Score =  128 bits (321), Expect = 1e-29
 Identities = 76/171 (44%), Positives = 86/171 (50%), Gaps = 17/171 (9%)

Query: 197 GPAGPPGQTGPPGPA--GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  GPPG  GPPG A  GPPG  G  G+ G+KG  GPPG+   PGP GL G+ G PG PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLPG 435

Query: 255 PPGPAG----------NPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           PPGPAG           PGP   P SP       +     D GD+      + T ++G P
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT--CFNCIGTGISGPP 493

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G  G PG PGPPG  G PG  G  G  G  G +G  G  G PG  G  G K
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544



 Score =  127 bits (319), Expect = 2e-29
 Identities = 77/185 (41%), Positives = 87/185 (47%), Gaps = 28/185 (15%)

Query: 190  PRQRRPTGPAGPPGQTGPPGP---AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P  +   G  G PG  GPPGP   +GPPG+ G  G+ G  G  G PG  GPPG +G PG+
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 247  MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL-------- 298
             G PGP G  G  G PG     P G      P      GD  L     +  L        
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGL-----PGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226

Query: 299  ----AGVPGPRGPPGPPGP--------PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGV 346
                 GV GP GPPG PGP        PGP+GPPG PG  G QGL G  G  G  G  G+
Sbjct: 1227 FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGI 1286

Query: 347  KGEEG 351
            KGE+G
Sbjct: 1287 KGEKG 1291



 Score =  127 bits (318), Expect = 3e-29
 Identities = 83/198 (41%), Positives = 92/198 (46%), Gaps = 17/198 (8%)

Query: 161  DNDLPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDR 220
            D  LP    TP    +  LP   P     P    P G +GPPG  G PG  GP G  G  
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLP-GFP---GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157

Query: 221  GQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPT 280
            GQ G  G  G PG  G PGP G  GE G+PG  G PGP G PG S     G L  +    
Sbjct: 1158 GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIP--- 1213

Query: 281  DKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGP--RGP---PGPPGTPGSQGLAGER 335
                G+  L     +    G PG +GPPGPPG PGP   GP   PGP G PG  G  G +
Sbjct: 1214 ----GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269

Query: 336  GTVGPSGEPGVKGEEGEK 353
            G  GP G PG+ G  G K
Sbjct: 1270 GLPGPEGPPGLPGNGGIK 1287



 Score =  125 bits (315), Expect = 6e-29
 Identities = 81/186 (43%), Positives = 88/186 (47%), Gaps = 39/186 (20%)

Query: 197 GPAGPPGQTGP--------PGPAGPPG---------SKGDRGQTGEKGPAGPPGLLGPPG 239
           GP GPPG  GP        PGP GPPG          KGDRG  G  GP G  GL G PG
Sbjct: 737 GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 240 PRGLPGEMGRPGPPGPP--------GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLAS 291
           P+G  G  G+PGP GPP        GP G PG      Q  L+ + P    D G   L  
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPPGLD- 854

Query: 292 AIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA------GERGTVGPSGEPG 345
                 + G PG RG PG PG PGP GPPG PG PG  G +      GE G +GP G PG
Sbjct: 855 ------VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 346 VKGEEG 351
             G  G
Sbjct: 909 PLGIPG 914



 Score =  125 bits (315), Expect = 6e-29
 Identities = 83/211 (39%), Positives = 97/211 (45%), Gaps = 26/211 (12%)

Query: 165  PAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTG 224
            P P  +P    E   P   P     P +  PTG  G PG  GPPG  G  G KG++G  G
Sbjct: 1237 PGPPGSPGPALEG--PKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPG 1294

Query: 225  E---------KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS--PNS--PQG 271
            +         KG  GPPGL G PG  GL G  G PG PG PG  G  GPS  P S  P+G
Sbjct: 1295 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEG 1354

Query: 272  ALYSLQPPTDKD-----------NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPP 320
                + PP                GD+          L G+PGP+GP G PGP GP G P
Sbjct: 1355 EPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP 1414

Query: 321  GPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            G  G PG  G  G +G  G  G+PG +G +G
Sbjct: 1415 GRNGLPGFDGAGGRKGDPGLPGQPGTRGLDG 1445



 Score =  125 bits (314), Expect = 8e-29
 Identities = 77/185 (41%), Positives = 88/185 (47%), Gaps = 26/185 (14%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P    P G  G PG  G PG +G PG  G  G  G  G  G PGL+GPPG +G  G+MG
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 249  RPGPPG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
             PGP G   PPGP+G PG  P SP        P    D GD  ++S      L G+PGP+
Sbjct: 1034 FPGPQGVEGPPGPSGVPG-QPGSPG------LPGQKGDKGDPGISSI----GLPGLPGPK 1082

Query: 306  GPPGPPG------------PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG             PG  G PG PG  G  GL G  GT GP G  G+ G  G  
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 354  AATAE 358
                E
Sbjct: 1143 GLPGE 1147



 Score =  125 bits (313), Expect = 1e-28
 Identities = 72/168 (42%), Positives = 81/168 (48%), Gaps = 36/168 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP---- 252
           G  G PG  G PGP G PG  G +G+ G  G  G PGL GPPGP G+PG  G PG     
Sbjct: 105 GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS 164

Query: 253 --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
             PGP G  G PGP        +  L  PT                   G+PGP GPPGP
Sbjct: 165 SLPGPKGNPGYPGPP------GIQGLPGPT-------------------GIPGPIGPPGP 199

Query: 311 PGPPGPRGPPGPPGTPGSQGL-----AGERGTVGPSGEPGVKGEEGEK 353
           PG  GP GPPG PG  G+ GL      GE+G  G  G PG  G+  E+
Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247



 Score =  124 bits (312), Expect = 1e-28
 Identities = 83/203 (40%), Positives = 94/203 (46%), Gaps = 33/203 (16%)

Query: 184  PLAHPVPRQRRPTG---PAGPPGQTGP------PGPAGPPGSKGDRGQTGEKG------- 227
            P   P P    P G   P GPPG+ GP      PGP GPPG  G+ G  GEKG       
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1298

Query: 228  --------PAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS--PNS--PQGALYS 275
                      GPPGL G PG  GL G  G PG PG PG  G  GPS  P S  P+G    
Sbjct: 1299 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL 1358

Query: 276  LQPPTDKDNGDSRLASAIVD-----TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQG 330
            + PP           S I+        + G PG +G PGP GP G  GP GPPG PG  G
Sbjct: 1359 IGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNG 1418

Query: 331  LAGERGTVGPSGEPGVKGEEGEK 353
            L G  G  G  G+PG+ G+ G +
Sbjct: 1419 LPGFDGAGGRKGDPGLPGQPGTR 1441



 Score =  124 bits (311), Expect = 2e-28
 Identities = 94/235 (40%), Positives = 103/235 (43%), Gaps = 44/235 (18%)

Query: 161  DNDLPAPESTPPTWNEDFLPDAIPLAHPVPR-QRRPTGPAGPPG-----QTGPPGPAGPP 214
            D   P P   P     D LP   P     P  Q  P GP G PG       GPPG  GP 
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPG--PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 215  GSKGDRGQTGEKGPAGPPGL--LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNS---- 268
            G  G  G  GEKG  GPPGL   GPPG RG PG  G PGP GPPG  G PG +  S    
Sbjct: 834  GQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 269  PQGALYSLQPPTDKDN----GDSRLASAIVDTVLAGVPGPRGP---------PGPPGPPG 315
             +G +  + PP         G S +     D  L G PG  GP         PG PGPPG
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 316  P-----------RGPPGPPGTPGS------QGLAGERGTVGPSGEPGVKGEEGEK 353
            P           +G PG PG PG       QGL G+ G  G SG+PG+ G  G K
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008



 Score =  123 bits (309), Expect = 3e-28
 Identities = 82/198 (41%), Positives = 94/198 (47%), Gaps = 46/198 (23%)

Query: 190 PRQRRPTGPAGPPGQT----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           P Q    GP G PGQT    G PG  G PG  GD G  G+ G  G PGL G PG +G PG
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702

Query: 246 --EMGRPGPPGPPGPAGNPGP--SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
              +G PGPPGP G  G PGP  +P +P G +    PP                    G 
Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTP-GRIGLEGPPGPP-----------------GF 744

Query: 302 PGPRGPPG-----PPGPPG---------PRG------PPGPPGTPGSQGLAGERGTVGPS 341
           PGP+G PG     PPGPPG         P+G      PPGPPG  G  GL G +G VGP+
Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 342 GEPGVKGEEGEKAATAEG 359
           G+PG  G  G      +G
Sbjct: 805 GQPGPMGPPGLPGIGVQG 822



 Score =  123 bits (309), Expect = 3e-28
 Identities = 73/177 (41%), Positives = 88/177 (49%), Gaps = 28/177 (15%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP------GEMGRP 250
            GP GPPG  G PG AG  G  G +G+ G  GP GPPG LG PG  G+P      G  G+P
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 251  GPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---- 305
            G PGP G  G+ G P    P G +      +  + G+  L        + GV GP+    
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQG 985

Query: 306  -----------GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
                       G PG PGPPGP+G PG PG PG  G  G +GT+G  G PG +G EG
Sbjct: 986  LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042



 Score =  122 bits (307), Expect = 5e-28
 Identities = 79/178 (44%), Positives = 86/178 (48%), Gaps = 22/178 (12%)

Query: 195 PTGPAGPPGQTG---PPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P G  G PG+ G   PPGP G PG KG+ G     GP GPPGL G  G  G  G+ G PG
Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 252 PPGPPGPAGNPG-PSPN---SPQGALYSLQPP------TDKDNGDSRLASAIVDTVLAGV 301
           PPGPPG  G  G P P     P G    + PP           G   +   I    L G+
Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 302 PGPRGPPGP-----PGPPGPRGPPGPPGTP---GSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G PGP     PGPPG RG PG PG P   G  G  G  G  G SG PG KGE G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899



 Score =  122 bits (306), Expect = 6e-28
 Identities = 73/172 (42%), Positives = 88/172 (51%), Gaps = 26/172 (15%)

Query: 197 GPAGPPGQTGPPGP-AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP-- 253
           GP GPPG  GPPGP  G  G KG++G+ G++G  G  G  G PG  GLPG+ G PG P  
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 254 ----------GPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
                     GPPGP G   P P +           T  + G+  L     +    G PG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGT---------GITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 304 PRGPPGPPGPPGP--RGPPGPPGTPGSQGLAGERGTVGPS--GEPGVKGEEG 351
            +GPPG PGPPG    GPPGPPG PG +G  G+ G  G S  G PG+ G+ G
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429



 Score =  122 bits (305), Expect = 8e-28
 Identities = 73/182 (40%), Positives = 84/182 (46%), Gaps = 19/182 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGS---KGDRGQTGEKGPAGPPGLLGPPGP-----------RG 242
           G  G  G  G PGP G PG    KG+RG  G  G  G PG +GP GP           +G
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           + G  G PG PG PGP G+PG +   P        P  D D G            L G+P
Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 303 GPRGPP-----GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
           G +G P     G PGPPGP+G PG PG PG+ G  G  G  GP G PG  G +GE     
Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 358 EG 359
            G
Sbjct: 756 PG 757



 Score =  121 bits (304), Expect = 1e-27
 Identities = 80/182 (43%), Positives = 88/182 (48%), Gaps = 36/182 (19%)

Query: 196 TGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP 255
           TG +GPPGQ G PG  GPPGS G  GQ GEKG A      G  GP+GLPG  G PG PG 
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA------GATGPKGLPGIPGAPGAPGF 540

Query: 256 PGPAGNPG-----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP------ 304
           PG  G PG     P     +G L S   P     G   L        L G+PGP      
Sbjct: 541 PGSKGEPGDILTFPGMKGDKGELGSPGAP-----GLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 305 ------RGPPGPPGPP------GPRGPP--GPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                 RGPPG PG P      GP GPP  GPPG  G +G+ G  G  G  G PG KG+ 
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 351 GE 352
           G+
Sbjct: 656 GQ 657



 Score =  119 bits (297), Expect = 7e-27
 Identities = 80/209 (38%), Positives = 93/209 (44%), Gaps = 55/209 (26%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL-------------- 235
           P +    G  G PG  G PG  G PG  G++GQ G+ GP GPPGL+              
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 236 --------GPPGPRGLPGEMGRPGPPGPPGPA--GNPGPSPNSP--QGALYSLQPPTDKD 283
                   G  G RG PG  G PG PGPPG A  G PGP P  P  +G      PP    
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP-PGFPGERGQKGDEGPPGISI 418

Query: 284 NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPR----------GPPGPPGTPGSQGLAG 333
            G            L G PG  G PGPPGP GP           GPPGPPG+PG +GL G
Sbjct: 419 PGPPG---------LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 334 ERGTVGPSGEPGVKGEEGEKAATAEGEGV 362
           E+         GVKG++G+      G G+
Sbjct: 470 EQ---------GVKGDKGDTCFNCIGTGI 489



 Score =  119 bits (297), Expect = 7e-27
 Identities = 77/185 (41%), Positives = 84/185 (45%), Gaps = 29/185 (15%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP---------RGLPGEM 247
            G  G PG  G PG  G PG+ G  G  G  GP G PGL G PGP          G PGE 
Sbjct: 1107 GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166

Query: 248  GRPGPPGPPGPA-----------GNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDT 296
            G+PG  G PGPA           GNPGP P  P  +            G+  L     + 
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGP-PGLPGLSGQKGDGGLPGIPGNPGLPGPKGEP 1225

Query: 297  VLAGVPGPRGPPGPPGPPGPR--------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
               G PG +GPPGPPG PGP         GP GPPG PG  G  G  G  GP G PG  G
Sbjct: 1226 GFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGG 1285

Query: 349  EEGEK 353
             +GEK
Sbjct: 1286 IKGEK 1290



 Score =  117 bits (294), Expect = 2e-26
 Identities = 82/191 (42%), Positives = 89/191 (46%), Gaps = 42/191 (21%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRG---------QTGEKGPAGPPGLLGPPGPR-----G 242
            GP GPPG  G PG +G PG KGD G          TGEKG  G PGL GPPGP      G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 243  LPGEMGRPGPPGPPGPAGNPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
              GE G PG PG PG +G  G    P  P     S QP      G         +  L G
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG------NPGLPG 1015

Query: 301  VPGPRGPPGP---------PGPPGPRGPPGP---PGTPGSQGLAGERG--------TVGP 340
             PG  GPPG          PGP G  GPPGP   PG PGS GL G++G        ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 341  SGEPGVKGEEG 351
             G PG KGE G
Sbjct: 1076 PGLPGPKGEPG 1086



 Score =  116 bits (290), Expect = 5e-26
 Identities = 79/198 (39%), Positives = 90/198 (45%), Gaps = 10/198 (5%)

Query: 157  PSSPDNDLPAPESTPPTWNE--DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            P  P    P P   P    +  D     IP    +P  +   G  G PG  GPPGP G P
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 215  GSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALY 274
            G   + G  G  GP GPPG  GP G +GLPG     GPPG PG  G  G   N  Q  L 
Sbjct: 1244 GPALE-GPKGNPGPQGPPGRPGPTGFQGLPGP---EGPPGLPGNGGIKGEKGNPGQPGLP 1299

Query: 275  SLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGE 334
             L P    D G   L     +    G+ G +G PG PG PG  G  GP G PGS G  GE
Sbjct: 1300 GL-PGLKGDQGPPGLQG---NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1355

Query: 335  RGTVGPSGEPGVKGEEGE 352
             G +GP G PG+ G  G+
Sbjct: 1356 PGLIGPPGPPGLPGPSGQ 1373



 Score =  111 bits (277), Expect = 1e-24
 Identities = 69/176 (39%), Positives = 76/176 (43%), Gaps = 40/176 (22%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRP----GP 252
            G  G  G  G PG  G PG KG  G  G  GP G PGL+GPPGP GLPG  G+     G 
Sbjct: 1321 GLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGD 1380

Query: 253  PGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
             GPPG  G PG    P P  PQG                             +PGP GPP
Sbjct: 1381 AGPPGIPGQPGLKGLPGPQGPQG-----------------------------LPGPTGPP 1411

Query: 309  GPPGP---PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEG 361
            G PG    PG  G  G  G PG  G  G RG  GP G  G++G  G    ++   G
Sbjct: 1412 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHG 1467



 Score =  108 bits (269), Expect = 1e-23
 Identities = 76/206 (36%), Positives = 90/206 (43%), Gaps = 47/206 (22%)

Query: 192 QRRPTGPAGPPG-------------QTGPPGPAGPPGSKGDRG------QTGEKGPAGPP 232
           Q+  TGP GPPG             + G  G  G PG KG+RG        G  GP G  
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-A 390

Query: 233 GLLGPPGPRGLPGEMGRPGP--------PGPPGPAGNPG-PSPNSPQGALYSLQPPTDK- 282
            ++GPPGP G PGE G+ G         PGPPG  G PG P    P G      PP+D+ 
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 283 -DNGDSRLASAIVDTVLAGVPGPR----------------GPPGPPGPPGPRGPPGPPGT 325
            + G      +  D  L G  G +                GPPG PG PG  GPPG  G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 326 PGSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G  G+ G  GP G PG+ G  G
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPG 536



 Score =  105 bits (261), Expect = 1e-22
 Identities = 71/193 (36%), Positives = 81/193 (41%), Gaps = 43/193 (22%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP----- 244
           P Q    G  GPPG        G PG KG++GQ G  GP G PG+ G PG  G P     
Sbjct: 493 PGQPGLPGLPGPPGS------LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 245 --------------GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
                         GE+G PG PG PG  G PG      Q  L  L  P  +  G     
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPG------QDGLPGLPGPKGEPGG----- 595

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPP--GTPGSQGLAGERGTVGPSGEPGVKG 348
                    G  GP G PG PG PG  GP GPP  G PG  G  G +G  G  G+PG+ G
Sbjct: 596 -----ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 349 EEGEKAATAEGEG 361
            +G+   T    G
Sbjct: 651 PKGDPGQTITQPG 663



 Score =  103 bits (257), Expect = 3e-22
 Identities = 71/174 (40%), Positives = 74/174 (42%), Gaps = 12/174 (6%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G  GP G+ G PG  G PG KG  G  G  G  G PG  G PG  G PG  G PGP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 257  GPAGNPG----PSPNSPQGALYSLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPP 311
            GP GNPG    P P    G      PP +K   G   +          G PG  G PGPP
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPP 1195

Query: 312  GPPGPRGP------PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
            G PG  G       PG PG PG  G  GE G  G  G  G  G  G      EG
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 49/124 (39%), Positives = 52/124 (41%), Gaps = 17/124 (13%)

Query: 164  LPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQT 223
            LP P         D  P  IP     P  +   GP GP G  GP GP G PG  G  G  
Sbjct: 1367 LPGPSGQSIIIKGDAGPPGIP---GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1423

Query: 224  GEKGPAGPPGLLGPPGPRGL---PGEMGRPGPPGPPGPA-----------GNPGPSPNSP 269
            G  G  G PGL G PG RGL   PG  G  GPPGPPG +                +P  P
Sbjct: 1424 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP 1483

Query: 270  QGAL 273
            QG L
Sbjct: 1484 QGTL 1487


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score =  139 bits (349), Expect = 7e-33
 Identities = 84/193 (43%), Positives = 95/193 (49%), Gaps = 22/193 (11%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQ---------TGEKGPAG 230
           P  IP  +    +R   G  G PG  GPPGP G PG KG+ G           G  G  G
Sbjct: 118 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177

Query: 231 PPGLLGPPGPRGLPGEMGRPGPP---GPPGPAGNPGPSPN------SPQG--ALYSLQPP 279
           PPG+ G PGP G+PG +G PGPP   GPPGP G PGP  N       P+G      LQ P
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  S     I      G  G  G  GPPGPPG RGPPGPPG  G +G  GE+G  G
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPG 295

Query: 340 PSGEPGVKGEEGE 352
             G+PG  GE G+
Sbjct: 296 KRGKPGKDGENGQ 308



 Score =  135 bits (339), Expect = 1e-31
 Identities = 85/224 (37%), Positives = 101/224 (45%), Gaps = 47/224 (20%)

Query: 165 PAPESTP-PTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGP------PGSK 217
           P P   P P     F     P    +P  +   GP G  G  GPPGP G       PG K
Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK 798

Query: 218 GDRGQTGEKGPAGPPGL-----LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGA 272
           GD G  G+ GP GPPGL      GPPGP G+PG +G+PG  G PG  G+PGP      G 
Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG- 857

Query: 273 LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP------------------ 314
                PP ++ +             + G PGP GPPG PG P                  
Sbjct: 858 -----PPGERGSPG-----------IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 315 GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           GP GPPGP G PG  G+ G +G  G  G+PG+ G  GEK +  E
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945



 Score =  132 bits (333), Expect = 5e-31
 Identities = 74/174 (42%), Positives = 89/174 (51%), Gaps = 14/174 (8%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP--- 253
           G  G PG  G PGP GPPG +G +G  G  GP GP G+ GPPG  G PG  G PG P   
Sbjct: 54  GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 254 GPPGPAGNPGPS--------PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
           G PGP G PG +        P SP      LQ P     G   +       +++ +PGP+
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSP--GFPGLQGPPGPP-GIPGMKGEPGSIIMSSLPGPK 170

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           G PG PGPPG +G PGP G PG  G  G  G +GP G PG+ G +G      +G
Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQG 224



 Score =  130 bits (327), Expect = 2e-30
 Identities = 73/168 (43%), Positives = 85/168 (50%), Gaps = 12/168 (7%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P +  P G  G PGQ GPPG  G PG  G  G  G+KG  G PG  G PGP GLPG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSG 1202

Query: 249  RPGPPGPPGPAGNPG-PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
            + G  G PG  GNPG P P    G      +Q P                  L G  G  
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG--------PALEGPKGNP 1254

Query: 306  GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            GP GPPG PG  GP GPPG PG+ G+ GE+G  G  G PG+ G +G++
Sbjct: 1255 GPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1302



 Score =  130 bits (326), Expect = 3e-30
 Identities = 75/171 (43%), Positives = 88/171 (51%), Gaps = 20/171 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP G PG  G PG  GPPG KG     G+ G  GP G+ GPPGP G+PG+ G PG PG
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGT---IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 255  PPGPAGNPG------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
              G  G+PG      P    P+G     +P      G+  +  ++ D  L G+PG  G  
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKG-----EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 309  GPPGPPGPRGPPGPP------GTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG  G PGPP      G PG+ GL GE G VG  G PG  G  GEK
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166



 Score =  129 bits (323), Expect = 7e-30
 Identities = 74/175 (42%), Positives = 87/175 (49%), Gaps = 13/175 (7%)

Query: 190  PRQRRPTGPAGPPGQTGPPGP---AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P  +   G  G PG  GPPGP   +GPPG+ G  G+ G  G  G PG  GPPG +G PG+
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 247  MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRG 306
             G PGP G  G  G PG     P G      P      GD  L     +    G+PGP+G
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGL-----PGLSGQKGDGGLPGIPGN---PGLPGPKG 1223

Query: 307  PPGPPGPPGPRGPPGPPGTPGS--QGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
             PG  G PG +GPPGPPG+PG   +G  G  G  GP G PG+ G EG       G
Sbjct: 1224 EPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNG 1278



 Score =  128 bits (322), Expect = 9e-30
 Identities = 82/201 (40%), Positives = 93/201 (46%), Gaps = 33/201 (16%)

Query: 184  PLAHPVPRQRRPTG---PAGPPGQTGPPGPAGPPGSKGDRGQTGE--------------- 225
            P   P P    P G   P GPPG+ G PGP GPPG  G+ G  GE               
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGL 1298

Query: 226  KGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPGPS--PNS--PQGALYSLQPPTD 281
            KG  GPPGL G PG  GL G  G PG PG PG  G  GPS  P S  P+G    + PP  
Sbjct: 1299 KGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP 1358

Query: 282  KD-----------NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQG 330
                          GD+          L G+PGP+GP G PGP GP G PG  G PG  G
Sbjct: 1359 PGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDG 1418

Query: 331  LAGERGTVGPSGEPGVKGEEG 351
              G +G  G  G+PG +G +G
Sbjct: 1419 AGGRKGDPGLPGQPGTRGLDG 1439



 Score =  128 bits (321), Expect = 1e-29
 Identities = 76/171 (44%), Positives = 86/171 (50%), Gaps = 17/171 (9%)

Query: 197 GPAGPPGQTGPPGPA--GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  GPPG  GPPG A  GPPG  G  G+ G+KG  GPPG+   PGP GL G+ G PG PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLPG 435

Query: 255 PPGPAG----------NPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           PPGPAG           PGP   P SP       +     D GD+      + T ++G P
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT--CFNCIGTGISGPP 493

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G  G PG PGPPG  G PG  G  G  G  G +G  G  G PG  G  G K
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544



 Score =  125 bits (315), Expect = 6e-29
 Identities = 81/186 (43%), Positives = 88/186 (47%), Gaps = 39/186 (20%)

Query: 197 GPAGPPGQTGP--------PGPAGPPG---------SKGDRGQTGEKGPAGPPGLLGPPG 239
           GP GPPG  GP        PGP GPPG          KGDRG  G  GP G  GL G PG
Sbjct: 737 GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 240 PRGLPGEMGRPGPPGPP--------GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLAS 291
           P+G  G  G+PGP GPP        GP G PG      Q  L+ + P    D G   L  
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPPGLD- 854

Query: 292 AIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA------GERGTVGPSGEPG 345
                 + G PG RG PG PG PGP GPPG PG PG  G +      GE G +GP G PG
Sbjct: 855 ------VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 346 VKGEEG 351
             G  G
Sbjct: 909 PLGIPG 914



 Score =  125 bits (314), Expect = 8e-29
 Identities = 77/185 (41%), Positives = 88/185 (47%), Gaps = 26/185 (14%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P    P G  G PG  G PG +G PG  G  G  G  G  G PGL+GPPG +G  G+MG
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 249  RPGPPG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
             PGP G   PPGP+G PG  P SP        P    D GD  ++S      L G+PGP+
Sbjct: 1034 FPGPQGVEGPPGPSGVPG-QPGSPG------LPGQKGDKGDPGISSI----GLPGLPGPK 1082

Query: 306  GPPGPPG------------PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG             PG  G PG PG  G  GL G  GT GP G  G+ G  G  
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 354  AATAE 358
                E
Sbjct: 1143 GLPGE 1147



 Score =  125 bits (313), Expect = 1e-28
 Identities = 72/168 (42%), Positives = 81/168 (48%), Gaps = 36/168 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP---- 252
           G  G PG  G PGP G PG  G +G+ G  G  G PGL GPPGP G+PG  G PG     
Sbjct: 105 GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS 164

Query: 253 --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
             PGP G  G PGP        +  L  PT                   G+PGP GPPGP
Sbjct: 165 SLPGPKGNPGYPGPP------GIQGLPGPT-------------------GIPGPIGPPGP 199

Query: 311 PGPPGPRGPPGPPGTPGSQGL-----AGERGTVGPSGEPGVKGEEGEK 353
           PG  GP GPPG PG  G+ GL      GE+G  G  G PG  G+  E+
Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247



 Score =  124 bits (311), Expect = 2e-28
 Identities = 94/235 (40%), Positives = 103/235 (43%), Gaps = 44/235 (18%)

Query: 161  DNDLPAPESTPPTWNEDFLPDAIPLAHPVPR-QRRPTGPAGPPG-----QTGPPGPAGPP 214
            D   P P   P     D LP   P     P  Q  P GP G PG       GPPG  GP 
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPG--PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 215  GSKGDRGQTGEKGPAGPPGL--LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNS---- 268
            G  G  G  GEKG  GPPGL   GPPG RG PG  G PGP GPPG  G PG +  S    
Sbjct: 834  GQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 269  PQGALYSLQPPTDKDN----GDSRLASAIVDTVLAGVPGPRGP---------PGPPGPPG 315
             +G +  + PP         G S +     D  L G PG  GP         PG PGPPG
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 316  P-----------RGPPGPPGTPGS------QGLAGERGTVGPSGEPGVKGEEGEK 353
            P           +G PG PG PG       QGL G+ G  G SG+PG+ G  G K
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008



 Score =  123 bits (309), Expect = 3e-28
 Identities = 82/198 (41%), Positives = 94/198 (47%), Gaps = 46/198 (23%)

Query: 190 PRQRRPTGPAGPPGQT----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           P Q    GP G PGQT    G PG  G PG  GD G  G+ G  G PGL G PG +G PG
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702

Query: 246 --EMGRPGPPGPPGPAGNPGP--SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
              +G PGPPGP G  G PGP  +P +P G +    PP                    G 
Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTP-GRIGLEGPPGPP-----------------GF 744

Query: 302 PGPRGPPG-----PPGPPG---------PRG------PPGPPGTPGSQGLAGERGTVGPS 341
           PGP+G PG     PPGPPG         P+G      PPGPPG  G  GL G +G VGP+
Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 342 GEPGVKGEEGEKAATAEG 359
           G+PG  G  G      +G
Sbjct: 805 GQPGPMGPPGLPGIGVQG 822



 Score =  123 bits (309), Expect = 3e-28
 Identities = 73/177 (41%), Positives = 88/177 (49%), Gaps = 28/177 (15%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP------GEMGRP 250
            GP GPPG  G PG AG  G  G +G+ G  GP GPPG LG PG  G+P      G  G+P
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 251  GPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---- 305
            G PGP G  G+ G P    P G +      +  + G+  L        + GV GP+    
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQG 985

Query: 306  -----------GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
                       G PG PGPPGP+G PG PG PG  G  G +GT+G  G PG +G EG
Sbjct: 986  LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042



 Score =  122 bits (307), Expect = 5e-28
 Identities = 79/178 (44%), Positives = 86/178 (48%), Gaps = 22/178 (12%)

Query: 195 PTGPAGPPGQTG---PPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P G  G PG+ G   PPGP G PG KG+ G     GP GPPGL G  G  G  G+ G PG
Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 252 PPGPPGPAGNPG-PSPN---SPQGALYSLQPP------TDKDNGDSRLASAIVDTVLAGV 301
           PPGPPG  G  G P P     P G    + PP           G   +   I    L G+
Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 302 PGPRGPPGP-----PGPPGPRGPPGPPGTP---GSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G PGP     PGPPG RG PG PG P   G  G  G  G  G SG PG KGE G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899



 Score =  122 bits (306), Expect = 6e-28
 Identities = 73/172 (42%), Positives = 88/172 (51%), Gaps = 26/172 (15%)

Query: 197 GPAGPPGQTGPPGP-AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP-- 253
           GP GPPG  GPPGP  G  G KG++G+ G++G  G  G  G PG  GLPG+ G PG P  
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 254 ----------GPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
                     GPPGP G   P P +           T  + G+  L     +    G PG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGT---------GITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 304 PRGPPGPPGPPGP--RGPPGPPGTPGSQGLAGERGTVGPS--GEPGVKGEEG 351
            +GPPG PGPPG    GPPGPPG PG +G  G+ G  G S  G PG+ G+ G
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429



 Score =  122 bits (305), Expect = 8e-28
 Identities = 73/182 (40%), Positives = 84/182 (46%), Gaps = 19/182 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGS---KGDRGQTGEKGPAGPPGLLGPPGP-----------RG 242
           G  G  G  G PGP G PG    KG+RG  G  G  G PG +GP GP           +G
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           + G  G PG PG PGP G+PG +   P        P  D D G            L G+P
Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 303 GPRGPP-----GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
           G +G P     G PGPPGP+G PG PG PG+ G  G  G  GP G PG  G +GE     
Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 358 EG 359
            G
Sbjct: 756 PG 757



 Score =  121 bits (304), Expect = 1e-27
 Identities = 80/182 (43%), Positives = 88/182 (48%), Gaps = 36/182 (19%)

Query: 196 TGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP 255
           TG +GPPGQ G PG  GPPGS G  GQ GEKG A      G  GP+GLPG  G PG PG 
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA------GATGPKGLPGIPGAPGAPGF 540

Query: 256 PGPAGNPG-----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP------ 304
           PG  G PG     P     +G L S   P     G   L        L G+PGP      
Sbjct: 541 PGSKGEPGDILTFPGMKGDKGELGSPGAP-----GLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 305 ------RGPPGPPGPP------GPRGPP--GPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                 RGPPG PG P      GP GPP  GPPG  G +G+ G  G  G  G PG KG+ 
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 351 GE 352
           G+
Sbjct: 656 GQ 657



 Score =  120 bits (301), Expect = 2e-27
 Identities = 87/214 (40%), Positives = 98/214 (45%), Gaps = 25/214 (11%)

Query: 157  PSSPDNDLPAPESTPPTWNE--DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            P  P    P P   P    +  D     IP    +P  +   G  G PG  GPPGP G P
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 215  GS--KGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQG 271
            G   +G +G  G +GP G PGL GP GP GLPG  G  G  G PG  G PG P     QG
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1303

Query: 272  ALYSLQPPTDKDN-GDSRLASAIVDTVLAGVP------GPRGPP---GPPGPPGPRGPPG 321
                  PP  + N G   L     D  L GVP      GP G P   GP G PG  GPPG
Sbjct: 1304 ------PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPG 1357

Query: 322  PPGTPGSQG----LAGERGTVGPSGEPGVKGEEG 351
            PPG PG  G    + G+ G  G  G+PG+KG  G
Sbjct: 1358 PPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1391



 Score =  119 bits (297), Expect = 7e-27
 Identities = 80/209 (38%), Positives = 93/209 (44%), Gaps = 55/209 (26%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL-------------- 235
           P +    G  G PG  G PG  G PG  G++GQ G+ GP GPPGL+              
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 236 --------GPPGPRGLPGEMGRPGPPGPPGPA--GNPGPSPNSP--QGALYSLQPPTDKD 283
                   G  G RG PG  G PG PGPPG A  G PGP P  P  +G      PP    
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP-PGFPGERGQKGDEGPPGISI 418

Query: 284 NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPR----------GPPGPPGTPGSQGLAG 333
            G            L G PG  G PGPPGP GP           GPPGPPG+PG +GL G
Sbjct: 419 PGPPG---------LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 334 ERGTVGPSGEPGVKGEEGEKAATAEGEGV 362
           E+         GVKG++G+      G G+
Sbjct: 470 EQ---------GVKGDKGDTCFNCIGTGI 489



 Score =  117 bits (294), Expect = 2e-26
 Identities = 82/191 (42%), Positives = 89/191 (46%), Gaps = 42/191 (21%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRG---------QTGEKGPAGPPGLLGPPGPR-----G 242
            GP GPPG  G PG +G PG KGD G          TGEKG  G PGL GPPGP      G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 243  LPGEMGRPGPPGPPGPAGNPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
              GE G PG PG PG +G  G    P  P     S QP      G         +  L G
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG------NPGLPG 1015

Query: 301  VPGPRGPPGP---------PGPPGPRGPPGP---PGTPGSQGLAGERG--------TVGP 340
             PG  GPPG          PGP G  GPPGP   PG PGS GL G++G        ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 341  SGEPGVKGEEG 351
             G PG KGE G
Sbjct: 1076 PGLPGPKGEPG 1086



 Score =  108 bits (269), Expect = 1e-23
 Identities = 76/206 (36%), Positives = 90/206 (43%), Gaps = 47/206 (22%)

Query: 192 QRRPTGPAGPPG-------------QTGPPGPAGPPGSKGDRG------QTGEKGPAGPP 232
           Q+  TGP GPPG             + G  G  G PG KG+RG        G  GP G  
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-A 390

Query: 233 GLLGPPGPRGLPGEMGRPGP--------PGPPGPAGNPG-PSPNSPQGALYSLQPPTDK- 282
            ++GPPGP G PGE G+ G         PGPPG  G PG P    P G      PP+D+ 
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 283 -DNGDSRLASAIVDTVLAGVPGPR----------------GPPGPPGPPGPRGPPGPPGT 325
            + G      +  D  L G  G +                GPPG PG PG  GPPG  G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 326 PGSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G  G+ G  GP G PG+ G  G
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPG 536



 Score =  105 bits (261), Expect = 1e-22
 Identities = 71/193 (36%), Positives = 81/193 (41%), Gaps = 43/193 (22%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP----- 244
           P Q    G  GPPG        G PG KG++GQ G  GP G PG+ G PG  G P     
Sbjct: 493 PGQPGLPGLPGPPGS------LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 245 --------------GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
                         GE+G PG PG PG  G PG      Q  L  L  P  +  G     
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPG------QDGLPGLPGPKGEPGG----- 595

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPP--GTPGSQGLAGERGTVGPSGEPGVKG 348
                    G  GP G PG PG PG  GP GPP  G PG  G  G +G  G  G+PG+ G
Sbjct: 596 -----ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 349 EEGEKAATAEGEG 361
            +G+   T    G
Sbjct: 651 PKGDPGQTITQPG 663



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 49/124 (39%), Positives = 52/124 (41%), Gaps = 17/124 (13%)

Query: 164  LPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQT 223
            LP P         D  P  IP     P  +   GP GP G  GP GP G PG  G  G  
Sbjct: 1361 LPGPSGQSIIIKGDAGPPGIP---GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1417

Query: 224  GEKGPAGPPGLLGPPGPRGL---PGEMGRPGPPGPPGPA-----------GNPGPSPNSP 269
            G  G  G PGL G PG RGL   PG  G  GPPGPPG +                +P  P
Sbjct: 1418 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP 1477

Query: 270  QGAL 273
            QG L
Sbjct: 1478 QGTL 1481


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score =  139 bits (349), Expect = 7e-33
 Identities = 84/193 (43%), Positives = 95/193 (49%), Gaps = 22/193 (11%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQ---------TGEKGPAG 230
           P  IP  +    +R   G  G PG  GPPGP G PG KG+ G           G  G  G
Sbjct: 118 PQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPG 177

Query: 231 PPGLLGPPGPRGLPGEMGRPGPP---GPPGPAGNPGPSPN------SPQG--ALYSLQPP 279
           PPG+ G PGP G+PG +G PGPP   GPPGP G PGP  N       P+G      LQ P
Sbjct: 178 PPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 280 TDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVG 339
                  S     I      G  G  G  GPPGPPG RGPPGPPG  G +G  GE+G  G
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPG 295

Query: 340 PSGEPGVKGEEGE 352
             G+PG  GE G+
Sbjct: 296 KRGKPGKDGENGQ 308



 Score =  135 bits (339), Expect = 1e-31
 Identities = 85/224 (37%), Positives = 101/224 (45%), Gaps = 47/224 (20%)

Query: 165 PAPESTP-PTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGP------PGSK 217
           P P   P P     F     P    +P  +   GP G  G  GPPGP G       PG K
Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPK 798

Query: 218 GDRGQTGEKGPAGPPGL-----LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGA 272
           GD G  G+ GP GPPGL      GPPGP G+PG +G+PG  G PG  G+PGP      G 
Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPG- 857

Query: 273 LYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPP------------------ 314
                PP ++ +             + G PGP GPPG PG P                  
Sbjct: 858 -----PPGERGSPG-----------IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 315 GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           GP GPPGP G PG  G+ G +G  G  G+PG+ G  GEK +  E
Sbjct: 902 GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE 945



 Score =  132 bits (333), Expect = 5e-31
 Identities = 74/174 (42%), Positives = 89/174 (51%), Gaps = 14/174 (8%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP--- 253
           G  G PG  G PGP GPPG +G +G  G  GP GP G+ GPPG  G PG  G PG P   
Sbjct: 54  GLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHD 113

Query: 254 GPPGPAGNPGPS--------PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
           G PGP G PG +        P SP      LQ P     G   +       +++ +PGP+
Sbjct: 114 GAPGPQGIPGCNGTKGERGFPGSP--GFPGLQGPPGPP-GIPGMKGEPGSIIMSSLPGPK 170

Query: 306 GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           G PG PGPPG +G PGP G PG  G  G  G +GP G PG+ G +G      +G
Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQG 224



 Score =  132 bits (332), Expect = 6e-31
 Identities = 75/178 (42%), Positives = 89/178 (50%), Gaps = 29/178 (16%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P +  P G  G PGQ GPPG  G PG  G  G  G+KG  G PG  G PGP GLPG  G
Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF-GNPGPPGLPGLSG 1202

Query: 249  R---------PGPPGPPGPAGNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVD 295
            +         PG PG PGP G PG    P    P G   S  P  +   G+         
Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN--------- 1253

Query: 296  TVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
                  PGP+GPPG PG  G  GP GPPG PG+ G+ GE+G  G  G PG+ G +G++
Sbjct: 1254 ------PGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQ 1305



 Score =  130 bits (326), Expect = 3e-30
 Identities = 75/171 (43%), Positives = 88/171 (51%), Gaps = 20/171 (11%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
            P GP G PG  G PG  GPPG KG     G+ G  GP G+ GPPGP G+PG+ G PG PG
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGT---IGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 255  PPGPAGNPG------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
              G  G+PG      P    P+G     +P      G+  +  ++ D  L G+PG  G  
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKG-----EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115

Query: 309  GPPGPPGPRGPPGPP------GTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG  G PGPP      G PG+ GL GE G VG  G PG  G  GEK
Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEK 1166



 Score =  130 bits (326), Expect = 3e-30
 Identities = 77/182 (42%), Positives = 87/182 (47%), Gaps = 25/182 (13%)

Query: 190  PRQRRPTGPAGPPGQTGPPGP---AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGE 246
            P  +   G  G PG  GPPGP   +GPPG+ G  G+ G  G  G PG  GPPG +G PG+
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 247  MGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA------- 299
             G PGP G  G  G PG     P G      P      GD  L     +  L        
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGL-----PGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226

Query: 300  --GVPGPRGPPGPPGPPGPR--------GPPGPPGTPGSQGLAGERGTVGPSGEPGVKGE 349
              G PG +GPPGPPG PGP         GP GPPG PG QGL G  G  G  G  G+KGE
Sbjct: 1227 FHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGE 1286

Query: 350  EG 351
            +G
Sbjct: 1287 KG 1288



 Score =  128 bits (321), Expect = 1e-29
 Identities = 76/171 (44%), Positives = 86/171 (50%), Gaps = 17/171 (9%)

Query: 197 GPAGPPGQTGPPGPA--GPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPG 254
           G  GPPG  GPPG A  GPPG  G  G+ G+KG  GPPG+   PGP GL G+ G PG PG
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLPG 435

Query: 255 PPGPAG----------NPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           PPGPAG           PGP   P SP       +     D GD+      + T ++G P
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDT--CFNCIGTGISGPP 493

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
           G  G PG PGPPG  G PG  G  G  G  G +G  G  G PG  G  G K
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544



 Score =  125 bits (315), Expect = 6e-29
 Identities = 81/186 (43%), Positives = 88/186 (47%), Gaps = 39/186 (20%)

Query: 197 GPAGPPGQTGP--------PGPAGPPG---------SKGDRGQTGEKGPAGPPGLLGPPG 239
           GP GPPG  GP        PGP GPPG          KGDRG  G  GP G  GL G PG
Sbjct: 737 GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 240 PRGLPGEMGRPGPPGPP--------GPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLAS 291
           P+G  G  G+PGP GPP        GP G PG      Q  L+ + P    D G   L  
Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI-PGEKGDPGPPGLD- 854

Query: 292 AIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLA------GERGTVGPSGEPG 345
                 + G PG RG PG PG PGP GPPG PG PG  G +      GE G +GP G PG
Sbjct: 855 ------VPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 346 VKGEEG 351
             G  G
Sbjct: 909 PLGIPG 914



 Score =  125 bits (314), Expect = 8e-29
 Identities = 77/185 (41%), Positives = 88/185 (47%), Gaps = 26/185 (14%)

Query: 189  VPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG 248
            +P    P G  G PG  G PG +G PG  G  G  G  G  G PGL+GPPG +G  G+MG
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 249  RPGPPG---PPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR 305
             PGP G   PPGP+G PG  P SP        P    D GD  ++S      L G+PGP+
Sbjct: 1034 FPGPQGVEGPPGPSGVPG-QPGSPG------LPGQKGDKGDPGISSI----GLPGLPGPK 1082

Query: 306  GPPGPPG------------PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G PG PG             PG  G PG PG  G  GL G  GT GP G  G+ G  G  
Sbjct: 1083 GEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNP 1142

Query: 354  AATAE 358
                E
Sbjct: 1143 GLPGE 1147



 Score =  125 bits (314), Expect = 8e-29
 Identities = 78/187 (41%), Positives = 88/187 (47%), Gaps = 30/187 (16%)

Query: 195  PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGE---------------KGPAGPPGLLGPPG 239
            P GP G PG  G PGP GPPG  G+ G  GE               KG  GPPGL G PG
Sbjct: 1256 PQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1315

Query: 240  PRGLPGEMGRPGPPGPPGPAGNPGPS--PNS--PQGALYSLQPPTDKD-----------N 284
              GL G  G PG PG PG  G  GPS  P S  P+G    + PP                
Sbjct: 1316 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1375

Query: 285  GDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEP 344
            GD+          L G+PGP+GP G PGP GP G PG  G PG  G  G +G  G  G+P
Sbjct: 1376 GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQP 1435

Query: 345  GVKGEEG 351
            G +G +G
Sbjct: 1436 GTRGLDG 1442



 Score =  125 bits (313), Expect = 1e-28
 Identities = 72/168 (42%), Positives = 81/168 (48%), Gaps = 36/168 (21%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGP---- 252
           G  G PG  G PGP G PG  G +G+ G  G  G PGL GPPGP G+PG  G PG     
Sbjct: 105 GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMS 164

Query: 253 --PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
             PGP G  G PGP        +  L  PT                   G+PGP GPPGP
Sbjct: 165 SLPGPKGNPGYPGPP------GIQGLPGPT-------------------GIPGPIGPPGP 199

Query: 311 PGPPGPRGPPGPPGTPGSQGL-----AGERGTVGPSGEPGVKGEEGEK 353
           PG  GP GPPG PG  G+ GL      GE+G  G  G PG  G+  E+
Sbjct: 200 PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQ 247



 Score =  124 bits (311), Expect = 2e-28
 Identities = 94/235 (40%), Positives = 103/235 (43%), Gaps = 44/235 (18%)

Query: 161  DNDLPAPESTPPTWNEDFLPDAIPLAHPVPR-QRRPTGPAGPPG-----QTGPPGPAGPP 214
            D   P P   P     D LP   P     P  Q  P GP G PG       GPPG  GP 
Sbjct: 776  DRGFPGPPGPPGRTGLDGLPG--PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 215  GSKGDRGQTGEKGPAGPPGL--LGPPGPRGLPGEMGRPGPPGPPGPAGNPGPSPNS---- 268
            G  G  G  GEKG  GPPGL   GPPG RG PG  G PGP GPPG  G PG +  S    
Sbjct: 834  GQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 269  PQGALYSLQPPTDKDN----GDSRLASAIVDTVLAGVPGPRGP---------PGPPGPPG 315
             +G +  + PP         G S +     D  L G PG  GP         PG PGPPG
Sbjct: 894  TKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPG 953

Query: 316  P-----------RGPPGPPGTPGS------QGLAGERGTVGPSGEPGVKGEEGEK 353
            P           +G PG PG PG       QGL G+ G  G SG+PG+ G  G K
Sbjct: 954  PMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008



 Score =  123 bits (309), Expect = 3e-28
 Identities = 82/198 (41%), Positives = 94/198 (47%), Gaps = 46/198 (23%)

Query: 190 PRQRRPTGPAGPPGQT----GPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPG 245
           P Q    GP G PGQT    G PG  G PG  GD G  G+ G  G PGL G PG +G PG
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702

Query: 246 --EMGRPGPPGPPGPAGNPGP--SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGV 301
              +G PGPPGP G  G PGP  +P +P G +    PP                    G 
Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTP-GRIGLEGPPGPP-----------------GF 744

Query: 302 PGPRGPPG-----PPGPPG---------PRG------PPGPPGTPGSQGLAGERGTVGPS 341
           PGP+G PG     PPGPPG         P+G      PPGPPG  G  GL G +G VGP+
Sbjct: 745 PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPN 804

Query: 342 GEPGVKGEEGEKAATAEG 359
           G+PG  G  G      +G
Sbjct: 805 GQPGPMGPPGLPGIGVQG 822



 Score =  123 bits (309), Expect = 3e-28
 Identities = 73/177 (41%), Positives = 88/177 (49%), Gaps = 28/177 (15%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP------GEMGRP 250
            GP GPPG  G PG AG  G  G +G+ G  GP GPPG LG PG  G+P      G  G+P
Sbjct: 872  GPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 251  GPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPR---- 305
            G PGP G  G+ G P    P G +      +  + G+  L        + GV GP+    
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG------IPGVSGPKGYQG 985

Query: 306  -----------GPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
                       G PG PGPPGP+G PG PG PG  G  G +GT+G  G PG +G EG
Sbjct: 986  LPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042



 Score =  122 bits (307), Expect = 5e-28
 Identities = 79/178 (44%), Positives = 86/178 (48%), Gaps = 22/178 (12%)

Query: 195 PTGPAGPPGQTG---PPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPG 251
           P G  G PG+ G   PPGP G PG KG+ G     GP GPPGL G  G  G  G+ G PG
Sbjct: 723 PPGAPGTPGRIGLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 252 PPGPPGPAGNPG-PSPN---SPQGALYSLQPP------TDKDNGDSRLASAIVDTVLAGV 301
           PPGPPG  G  G P P     P G    + PP           G   +   I    L G+
Sbjct: 782 PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 302 PGPRGPPGP-----PGPPGPRGPPGPPGTP---GSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G PGP     PGPPG RG PG PG P   G  G  G  G  G SG PG KGE G
Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899



 Score =  122 bits (306), Expect = 6e-28
 Identities = 73/172 (42%), Positives = 88/172 (51%), Gaps = 26/172 (15%)

Query: 197 GPAGPPGQTGPPGP-AGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPP-- 253
           GP GPPG  GPPGP  G  G KG++G+ G++G  G  G  G PG  GLPG+ G PG P  
Sbjct: 267 GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGR 326

Query: 254 ----------GPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPG 303
                     GPPGP G   P P +           T  + G+  L     +    G PG
Sbjct: 327 DGEKGQKGDTGPPGPPGLVIPRPGT---------GITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 304 PRGPPGPPGPPGP--RGPPGPPGTPGSQGLAGERGTVGPS--GEPGVKGEEG 351
            +GPPG PGPPG    GPPGPPG PG +G  G+ G  G S  G PG+ G+ G
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429



 Score =  122 bits (305), Expect = 8e-28
 Identities = 73/182 (40%), Positives = 84/182 (46%), Gaps = 19/182 (10%)

Query: 197 GPAGPPGQTGPPGPAGPPGS---KGDRGQTGEKGPAGPPGLLGPPGP-----------RG 242
           G  G  G  G PGP G PG    KG+RG  G  G  G PG +GP GP           +G
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 243 LPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVP 302
           + G  G PG PG PGP G+PG +   P        P  D D G            L G+P
Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 303 GPRGPP-----GPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATA 357
           G +G P     G PGPPGP+G PG PG PG+ G  G  G  GP G PG  G +GE     
Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 358 EG 359
            G
Sbjct: 756 PG 757



 Score =  121 bits (304), Expect = 1e-27
 Identities = 80/182 (43%), Positives = 88/182 (48%), Gaps = 36/182 (19%)

Query: 196 TGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGP 255
           TG +GPPGQ G PG  GPPGS G  GQ GEKG A      G  GP+GLPG  G PG PG 
Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA------GATGPKGLPGIPGAPGAPGF 540

Query: 256 PGPAGNPG-----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP------ 304
           PG  G PG     P     +G L S   P     G   L        L G+PGP      
Sbjct: 541 PGSKGEPGDILTFPGMKGDKGELGSPGAP-----GLPGLPGTPGQDGLPGLPGPKGEPGG 595

Query: 305 ------RGPPGPPGPP------GPRGPP--GPPGTPGSQGLAGERGTVGPSGEPGVKGEE 350
                 RGPPG PG P      GP GPP  GPPG  G +G+ G  G  G  G PG KG+ 
Sbjct: 596 ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655

Query: 351 GE 352
           G+
Sbjct: 656 GQ 657



 Score =  119 bits (297), Expect = 7e-27
 Identities = 80/209 (38%), Positives = 93/209 (44%), Gaps = 55/209 (26%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLL-------------- 235
           P +    G  G PG  G PG  G PG  G++GQ G+ GP GPPGL+              
Sbjct: 300 PGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKG 359

Query: 236 --------GPPGPRGLPGEMGRPGPPGPPGPA--GNPGPSPNSP--QGALYSLQPPTDKD 283
                   G  G RG PG  G PG PGPPG A  G PGP P  P  +G      PP    
Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP-PGFPGERGQKGDEGPPGISI 418

Query: 284 NGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPR----------GPPGPPGTPGSQGLAG 333
            G            L G PG  G PGPPGP GP           GPPGPPG+PG +GL G
Sbjct: 419 PGPPG---------LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 334 ERGTVGPSGEPGVKGEEGEKAATAEGEGV 362
           E+         GVKG++G+      G G+
Sbjct: 470 EQ---------GVKGDKGDTCFNCIGTGI 489



 Score =  117 bits (294), Expect = 2e-26
 Identities = 82/191 (42%), Positives = 89/191 (46%), Gaps = 42/191 (21%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRG---------QTGEKGPAGPPGLLGPPGPR-----G 242
            GP GPPG  G PG +G PG KGD G          TGEKG  G PGL GPPGP      G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 243  LPGEMGRPGPPGPPGPAGNPGPS--PNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
              GE G PG PG PG +G  G    P  P     S QP      G         +  L G
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG------NPGLPG 1015

Query: 301  VPGPRGPPGP---------PGPPGPRGPPGP---PGTPGSQGLAGERG--------TVGP 340
             PG  GPPG          PGP G  GPPGP   PG PGS GL G++G        ++G 
Sbjct: 1016 QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGL 1075

Query: 341  SGEPGVKGEEG 351
             G PG KGE G
Sbjct: 1076 PGLPGPKGEPG 1086



 Score =  115 bits (288), Expect = 8e-26
 Identities = 87/231 (37%), Positives = 99/231 (42%), Gaps = 39/231 (16%)

Query: 157  PSSPDNDLPAPESTPPTWNE--DFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPP 214
            P  P    P P   P    +  D     IP    +P  +   G  G PG  GPPGP G P
Sbjct: 1184 PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSP 1243

Query: 215  GS--KGDRGQTGEKGPAGPPGLLGPPGPRGLP---------GEMGRPGPP---------- 253
            G   +G +G  G +GP G PG  G PGP G P         GE G PG P          
Sbjct: 1244 GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1303

Query: 254  --GPPGPAGNPG-PSPNSPQG--ALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPP 308
              GPPG  GNPG P  N  +G   L  + P      G S +  +       G PG  GPP
Sbjct: 1304 DQGPPGLQGNPGRPGLNGMKGDPGLPGV-PGFPGMKGPSGVPGSAGP---EGEPGLIGPP 1359

Query: 309  GPPGPPGP-------RGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            GPPG PGP       +G  GPPG PG  GL G  G  GP G PG  G  G+
Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1410



 Score =  108 bits (269), Expect = 1e-23
 Identities = 76/206 (36%), Positives = 90/206 (43%), Gaps = 47/206 (22%)

Query: 192 QRRPTGPAGPPG-------------QTGPPGPAGPPGSKGDRG------QTGEKGPAGPP 232
           Q+  TGP GPPG             + G  G  G PG KG+RG        G  GP G  
Sbjct: 332 QKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-A 390

Query: 233 GLLGPPGPRGLPGEMGRPGP--------PGPPGPAGNPG-PSPNSPQGALYSLQPPTDK- 282
            ++GPPGP G PGE G+ G         PGPPG  G PG P    P G      PP+D+ 
Sbjct: 391 AVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEI 450

Query: 283 -DNGDSRLASAIVDTVLAGVPGPR----------------GPPGPPGPPGPRGPPGPPGT 325
            + G      +  D  L G  G +                GPPG PG PG  GPPG  G 
Sbjct: 451 CEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF 510

Query: 326 PGSQGLAGERGTVGPSGEPGVKGEEG 351
           PG +G  G+ G  GP G PG+ G  G
Sbjct: 511 PGQKGEKGQAGATGPKGLPGIPGAPG 536



 Score =  105 bits (261), Expect = 1e-22
 Identities = 71/193 (36%), Positives = 81/193 (41%), Gaps = 43/193 (22%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLP----- 244
           P Q    G  GPPG        G PG KG++GQ G  GP G PG+ G PG  G P     
Sbjct: 493 PGQPGLPGLPGPPGS------LGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGE 546

Query: 245 --------------GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLA 290
                         GE+G PG PG PG  G PG      Q  L  L  P  +  G     
Sbjct: 547 PGDILTFPGMKGDKGELGSPGAPGLPGLPGTPG------QDGLPGLPGPKGEPGG----- 595

Query: 291 SAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPP--GTPGSQGLAGERGTVGPSGEPGVKG 348
                    G  GP G PG PG PG  GP GPP  G PG  G  G +G  G  G+PG+ G
Sbjct: 596 -----ITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 349 EEGEKAATAEGEG 361
            +G+   T    G
Sbjct: 651 PKGDPGQTITQPG 663



 Score =  103 bits (257), Expect = 3e-22
 Identities = 71/174 (40%), Positives = 74/174 (42%), Gaps = 12/174 (6%)

Query: 197  GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
            G  GP G+ G PG  G PG KG  G  G  G  G PG  G PG  G PG  G PGP G  
Sbjct: 1077 GLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGIS 1136

Query: 257  GPAGNPG----PSPNSPQGALYSLQPPTDKDN-GDSRLASAIVDTVLAGVPGPRGPPGPP 311
            GP GNPG    P P    G      PP +K   G   +          G PG  G PGPP
Sbjct: 1137 GPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPP 1195

Query: 312  GPPGPRGP------PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
            G PG  G       PG PG PG  G  GE G  G  G  G  G  G      EG
Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249



 Score = 73.6 bits (179), Expect = 3e-13
 Identities = 49/124 (39%), Positives = 52/124 (41%), Gaps = 17/124 (13%)

Query: 164  LPAPESTPPTWNEDFLPDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQT 223
            LP P         D  P  IP     P  +   GP GP G  GP GP G PG  G  G  
Sbjct: 1364 LPGPSGQSIIIKGDAGPPGIP---GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFD 1420

Query: 224  GEKGPAGPPGLLGPPGPRGL---PGEMGRPGPPGPPGPA-----------GNPGPSPNSP 269
            G  G  G PGL G PG RGL   PG  G  GPPGPPG +                +P  P
Sbjct: 1421 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCP 1480

Query: 270  QGAL 273
            QG L
Sbjct: 1481 QGTL 1484


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  139 bits (349), Expect = 7e-33
 Identities = 84/177 (47%), Positives = 91/177 (51%), Gaps = 14/177 (7%)

Query: 189 VPRQRRPTGPAGPPG--QTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG---- 242
           +P  + PTGP+GPPG  + G  G  G PG KGDRG  GE GP GPPG  GPPG RG    
Sbjct: 204 LPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI 263

Query: 243 -LPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAG 300
             PG  G PG PG PG  G PG P    P G     +P      G+   A         G
Sbjct: 264 GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKG 323

Query: 301 VPGPRGPPGPPG---PPGPRGPPGPPGTPGSQGL---AGERGTVGPSGEPGVKGEEG 351
             GP G PG PG   PPG  GP GP G PGS GL    GE G  GP+G PG KGE G
Sbjct: 324 EQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380



 Score =  135 bits (341), Expect = 6e-32
 Identities = 80/182 (43%), Positives = 91/182 (50%), Gaps = 23/182 (12%)

Query: 180 PDAIPLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPG 239
           P  IP +H +P  +  TGPAGP G  G  G  G PGS G  G  G+ G  GP G  G PG
Sbjct: 348 PKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPG 407

Query: 240 PRGLPGEMGRPGPPGPPGPAGNPG-PSPN---SPQGALYSLQPPTDKDNGDSRLASAIVD 295
           P+G PG  G PG PGP GPAG  G P  N    P+GA            G       I  
Sbjct: 408 PKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA-----------PGIPGTRGPIGP 456

Query: 296 TVLAGVPGPRGPPGPPGPPGP--------RGPPGPPGTPGSQGLAGERGTVGPSGEPGVK 347
             + G PG +G PG PGPPGP         GP GPPG PG +G +GE G  GP G PG  
Sbjct: 457 PGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPP 516

Query: 348 GE 349
           G+
Sbjct: 517 GQ 518



 Score =  133 bits (335), Expect = 3e-31
 Identities = 79/172 (45%), Positives = 87/172 (50%), Gaps = 19/172 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G  GPPG  GP GP G PGS G  G  GE GPAGP G  G  G RG PG  G+PG PG P
Sbjct: 335 GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKP 394

Query: 257 G---PAGNPG-------PSPNSPQGALYSLQPPTDKD----NGDSRLASAIVDTVLAGVP 302
           G   P GNPG       P    P G    + P   K     NG++    A     + G  
Sbjct: 395 GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA---PGIPGTR 451

Query: 303 GPRGPPGPPGPPGPRGPPGPPGTPGSQGLA--GERGTVGPSGEPGVKGEEGE 352
           GP GPPG PG PG +G PG PG PG  G+A  G  G  GP G PG +G  GE
Sbjct: 452 GPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGE 503



 Score =  127 bits (319), Expect = 2e-29
 Identities = 80/193 (41%), Positives = 94/193 (48%), Gaps = 25/193 (12%)

Query: 183 IPLAHPVPRQRRPTGPAGPPG-----------QTGPPGPAGPPGSKGDRGQTG---EKGP 228
           IP    +P      GP GPPG           + GP G  G PG+KG++G  G   + G 
Sbjct: 277 IPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGL 336

Query: 229 AGPPGLLGPPGPRGLPGEMGRPGPPG---PPGPAGNPGP-----SPNSPQGALYSLQPPT 280
            GPPG +GP GP+G+PG  G PGP G   P GPAG PG      SP S     Y  +P  
Sbjct: 337 TGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGL 396

Query: 281 DKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGP 340
           D   G+  L     D    GV GP G PGP GP G +G PG  G  G +G  G  GT GP
Sbjct: 397 DGPKGNPGLPGPKGDP---GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP 453

Query: 341 SGEPGVKGEEGEK 353
            G PG+ G  G K
Sbjct: 454 IGPPGIPGFPGSK 466



 Score =  125 bits (314), Expect = 8e-29
 Identities = 74/186 (39%), Positives = 85/186 (45%), Gaps = 29/186 (15%)

Query: 188 PVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL--PG 245
           P P      G  G PG  G PG  GP G KGD G  G  GP GPPG  G PGP G+  PG
Sbjct: 97  PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPG 156

Query: 246 EMGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           + G+ GP G PGP G PG       P  N  +G +    P    +               
Sbjct: 157 KPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGER-------------- 202

Query: 299 AGVPGPRGPPGPPGPP-----GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
            G+PGP+GP GP GPP     G  G PG PG  G +G  GE G +GP G  G  GE G +
Sbjct: 203 -GLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPE 261

Query: 354 AATAEG 359
                G
Sbjct: 262 GIGKPG 267



 Score =  122 bits (307), Expect = 5e-28
 Identities = 88/233 (37%), Positives = 93/233 (39%), Gaps = 66/233 (28%)

Query: 157 PSSPDND-----LPAPESTPPTWNEDFLPDAIP--LAHPVPRQRRPTGPAGPPGQTGPPG 209
           P  P  D     LP P   P        P  IP      VP +    GP G PG  G PG
Sbjct: 122 PYGPKGDVGPAGLPGPRGPPG-------PPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174

Query: 210 PAGPPGSKGDRGQTGE--------------KGPAGPPGLLGPP----------------- 238
             G PG  G  GQ GE               GP GP G  GPP                 
Sbjct: 175 EKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234

Query: 239 GPRGLPGEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVL 298
           G RG PGEMG  GPPGP GP G  GP      GA  +   P                   
Sbjct: 235 GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQP------------------- 275

Query: 299 AGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
            G+PG +G PG PG  GP GPPG  G PG  GL GERG  G  G PG KGE+G
Sbjct: 276 -GIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQG 326



 Score =  122 bits (306), Expect = 6e-28
 Identities = 73/176 (41%), Positives = 87/176 (49%), Gaps = 20/176 (11%)

Query: 197 GPAGPP--GQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMG--RPGP 252
           GP GP   G+ G PG  G PG +G  G  G+ GPAG PG  GPPGP G+PG  G   PG 
Sbjct: 98  GPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157

Query: 253 PGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           PG  GP G PGP     +     + P  +   G+    +        G PG RG PGP G
Sbjct: 158 PGQQGPTGAPGPRGFPGEKGAPGV-PGMNGQKGEMGYGA-------PGRPGERGLPGPQG 209

Query: 313 PPGPRGPP--------GPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGE 360
           P GP GPP        G PG PG +G  G  G +GP G PG +G  GE+     G+
Sbjct: 210 PTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGK 265



 Score =  114 bits (284), Expect = 2e-25
 Identities = 75/177 (42%), Positives = 82/177 (46%), Gaps = 14/177 (7%)

Query: 191 RQRRPTGPAGPPGQTGP----PGPAGPPGS--KGDRGQTGEKGPAGPPGLLGPPGPRGLP 244
           R + PTG  GP   T      P      G   +G++G  G  GPAGP G  GP GP G P
Sbjct: 24  RYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKP 83

Query: 245 GEMGRPGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGP 304
           G  G PG  G PG  G PGPS     G      P      G+        D   AG+PGP
Sbjct: 84  G-YGSPGLQGEPGLPGPPGPSAVGKPGV-----PGLPGKPGERGPYGPKGDVGPAGLPGP 137

Query: 305 RGPPGPPGPPGPRG--PPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEG 359
           RGPPGPPG PGP G   PG PG  G  G  G RG  G  G PGV G  G+K     G
Sbjct: 138 RGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYG 194



 Score = 82.4 bits (202), Expect = 7e-16
 Identities = 60/166 (36%), Positives = 70/166 (42%), Gaps = 19/166 (11%)

Query: 164 LPAPESTPPTWNEDFLPDAIPLAHP--VPRQRRPTGPAGPPGQTGPPGPAGPPG------ 215
           LP P+  P       LP  +  A    +P      GP G PG  G  GP GPPG      
Sbjct: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464

Query: 216 SKGDRGQTGEKGPAG--------PPGLLGPPGPRGLPGEMGRPGPP---GPPGPAGNPGP 264
           SKGD G  G  GPAG        P G  GPPGPRG  GE G PGPP   GPPG A  P  
Sbjct: 465 SKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEG 524

Query: 265 SPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGP 310
              + Q    S  P    + G + +  +    +L+      G P P
Sbjct: 525 FIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIP 570


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  138 bits (348), Expect = 9e-33
 Identities = 84/187 (44%), Positives = 94/187 (50%), Gaps = 40/187 (21%)

Query: 190 PRQRRPTGPAGPP---------GQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGP 240
           P +R P GP GPP         G  GPPG AGPPG KG+ G+ G  GP G PG+ G  G 
Sbjct: 29  PGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGA 88

Query: 241 RGLPGEMGRP---GPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTV 297
           +G PG MG P   G PG PGP G PGP    P G      PP     G   L   I    
Sbjct: 89  KGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPG------PP-----GPVGLPGEI---- 133

Query: 298 LAGVPGPRGPPGPPGPPGPRGPPGPPGTPGS-QGLAGER----------GTVGPSGEPGV 346
             G+ GP+G PGP GP GP GPPG PG PG+ QGL G            G  GP G  GV
Sbjct: 134 --GIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGV 191

Query: 347 KGEEGEK 353
           KG  G++
Sbjct: 192 KGHAGKR 198



 Score =  134 bits (338), Expect = 1e-31
 Identities = 84/214 (39%), Positives = 98/214 (45%), Gaps = 45/214 (21%)

Query: 184 PLAHPVPRQRR-PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRG 242
           P+  P P+ R+ P G  GPPG  GP G  G  G KG  G+TG +G  G PG+ G PG +G
Sbjct: 395 PVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKG 454

Query: 243 LPGEMGRPGP------------PGPPGPAGNPG----PSPNSPQGALYSL----QPPTDK 282
             GE G PGP            PGP G AG PG    P P  P+G   +     QP    
Sbjct: 455 EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQG 514

Query: 283 DNGDSRLASAIVDTVL---------------------AGVPGPRGPPGPPGPPGPRGP-- 319
             G       IVD  L                      G+ GP GPPGPPG PG +GP  
Sbjct: 515 VEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHG 574

Query: 320 -PGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
            PGP G PG  G  G+ G  GP G+ G KG+ GE
Sbjct: 575 HPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGE 608



 Score =  129 bits (324), Expect = 5e-30
 Identities = 78/185 (42%), Positives = 88/185 (47%), Gaps = 24/185 (12%)

Query: 190 PRQRRPTGPAGPPGQTGPPG------PAGPPGSKGDRGQTGEKGPAGPPGLLG---PPGP 240
           P  R P G  GP G TGPPG        G PG KG  GQ G+ G  G  GL G    PG 
Sbjct: 285 PGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGT 344

Query: 241 RGLPGEMGRPGP------PGPPGPAGNPGPSPN-SPQGALYSLQPPTDKDNGDSRLASAI 293
           +G PG+ G PGP       GPPG  G PGP     PQG +           GD      +
Sbjct: 345 KGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIM--------GQKGDQGERGPV 396

Query: 294 VDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEK 353
                 G  GP+G  GPPG PGP+G PG  G  GS G  G RG VG  G  G+ GE+GEK
Sbjct: 397 GQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEK 456

Query: 354 AATAE 358
             + E
Sbjct: 457 GESGE 461



 Score =  126 bits (316), Expect = 4e-29
 Identities = 73/163 (44%), Positives = 82/163 (50%), Gaps = 19/163 (11%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGP---AGPPGLLGPPGPRGLPGEMGRPGPP 253
           G  GPPG+ GP GP G  G KGD G  G +GP    GP G  GPPG  G  G  G PG  
Sbjct: 259 GATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMK 318

Query: 254 GPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGP 313
           G  G AG PG SP     A    QP T    GD             G PGP+G PG  GP
Sbjct: 319 GSAGQAGQPG-SPGHQGLAGVPGQPGTKGGPGDQ------------GEPGPQGLPGFSGP 365

Query: 314 PGPRGPPGPPGTPGSQGLAGERGTV---GPSGEPGVKGEEGEK 353
           PG  G PGP G  G QG+ G++G     GP G+PG +G +G K
Sbjct: 366 PGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPK 408



 Score =  120 bits (301), Expect = 2e-27
 Identities = 75/196 (38%), Positives = 92/196 (46%), Gaps = 37/196 (18%)

Query: 179 LPDAIPLAHPV--PRQRRPTGPAGPPGQTG--------------------PPGPAGPPGS 216
           LP  I +  P   P    P+GP GPPG+ G                    PPG  GPPG 
Sbjct: 129 LPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGL 188

Query: 217 KGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPAGNPG-PSPNSPQGALYS 275
           +G +G  G++G  G PG  G PGP+G  G  G  G PGPPGP G  G P    P+G    
Sbjct: 189 QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKG---- 244

Query: 276 LQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGER 335
                   +G   +  AI  T   G PG  GP GPPG  G +G  G PG  G QG+ G +
Sbjct: 245 ----ETGPHGYKGMVGAIGAT---GPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297

Query: 336 GTVGPSGEPGVKGEEG 351
           G  GP   PG+ G++G
Sbjct: 298 GATGP---PGINGKDG 310



 Score =  120 bits (301), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 89/180 (49%), Gaps = 27/180 (15%)

Query: 190 PRQRRPTGPAGPPGQTGPPGPAGPPGSKGD---RGQTGEKGPAGPPGLLGPPGPRGLPGE 246
           P  +   GP G PG +GPPG  G PG +G+   +G  G+KG  G  G +G PGP+G  G 
Sbjct: 348 PGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGP 407

Query: 247 MGRPGPPGPPGPAGNPG-------PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLA 299
            G  GPPG PGP G PG       P    P+G +         D G + L     +   +
Sbjct: 408 KGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKV--------GDPGVAGLPGEKGEKGES 459

Query: 300 GVPGP------RGPPGPPGPPGPRGPPGP---PGTPGSQGLAGERGTVGPSGEPGVKGEE 350
           G PGP      RG PG PGP G  G PG    PG PG +GLAG RG  G  G  GV+G +
Sbjct: 460 GEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRD 519



 Score =  119 bits (297), Expect = 7e-27
 Identities = 69/170 (40%), Positives = 79/170 (46%), Gaps = 35/170 (20%)

Query: 200 GPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPPGPA 259
           GPPG+ GPPGP GPP   G  G  G  G  GPPG  GPPGP+G PG+ G  GP G PG  
Sbjct: 27  GPPGERGPPGPPGPP---GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGID 83

Query: 260 GNPG----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPGP-- 313
           G  G    P P    G                          + G PG  GPPG PGP  
Sbjct: 84  GLTGAKGEPGPMGIPG--------------------------VKGQPGLPGPPGLPGPGF 117

Query: 314 PGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAEGEGVQ 363
            GP GPPGP G PG  G+ G +G  GP G  G  G  G+       +G++
Sbjct: 118 AGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLE 167



 Score =  119 bits (297), Expect = 7e-27
 Identities = 68/167 (40%), Positives = 83/167 (49%), Gaps = 11/167 (6%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGRPGPPGPP 256
           G AGP G+TGP G  G  G+ G  G  GE+GP GPPG  G  G  G PG  G  G  GP 
Sbjct: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297

Query: 257 GPAGNPG-----PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPP 311
           G  G PG      +P +P     + Q       G   LA       + G PG +G PG  
Sbjct: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG------VPGQPGTKGGPGDQ 351

Query: 312 GPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGEKAATAE 358
           G PGP+G PG  G PG +G  G RG +GP G  G KG++GE+    +
Sbjct: 352 GEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQ 398



 Score =  113 bits (282), Expect = 4e-25
 Identities = 65/159 (40%), Positives = 75/159 (47%), Gaps = 30/159 (18%)

Query: 197 GPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAG---PPGLLGPPGPRGLPGEMGRPGPP 253
           G  G PG  G PGP G PG  G  G+ GE GP G   P G++G  G +G  G +G+PGP 
Sbjct: 343 GTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQ 402

Query: 254 GPPGPAGNPG-PSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPGPPG 312
           G  GP G  G P    PQG                          L GV G +G PG  G
Sbjct: 403 GRQGPKGEQGPPGIPGPQG--------------------------LPGVKGDKGSPGKTG 436

Query: 313 PPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           P G  G PG  G PG +G  GE G  GP G+ GV+GE G
Sbjct: 437 PRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPG 475



 Score = 87.8 bits (216), Expect = 2e-17
 Identities = 54/138 (39%), Positives = 58/138 (42%), Gaps = 37/138 (26%)

Query: 195 PTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGLPGEMGR----- 249
           P GP GPPG  G  GP G PG +G  G  G  G  G  G  G  G +G PGE+GR     
Sbjct: 557 PPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGM 616

Query: 250 PGPPGPPGPAGNPGPSPNSPQGALYSLQPPTDKDNGDSRLASAIVDTVLAGVPGPRGPPG 309
           PGPPG PG  G PG + N                                G  G RG PG
Sbjct: 617 PGPPGIPGLPGRPGQAIN--------------------------------GKDGDRGSPG 644

Query: 310 PPGPPGPRGPPGPPGTPG 327
            PG  G  G PGP G PG
Sbjct: 645 APGEAGRPGLPGPVGLPG 662



 Score = 68.6 bits (166), Expect = 1e-11
 Identities = 32/65 (49%), Positives = 37/65 (56%), Gaps = 9/65 (13%)

Query: 298 LAGVPGPRGPPGPPGPP---------GPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKG 348
           + G PG RGPPGPPGPP         G  GPPG  G PG +G  G+ G  GP G+PG+ G
Sbjct: 25  IRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDG 84

Query: 349 EEGEK 353
             G K
Sbjct: 85  LTGAK 89



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 43/93 (46%), Positives = 43/93 (46%), Gaps = 15/93 (16%)

Query: 184 PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGD-----RGQTGEKGPAGPPGLLGPP 238
           P  HP PR     G  G  GQ G  GP G  G KGD     RG  G  GP G PGL G P
Sbjct: 572 PHGHPGPRG--VPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRP 629

Query: 239 --------GPRGLPGEMGRPGPPGPPGPAGNPG 263
                   G RG PG  G  G PG PGP G PG
Sbjct: 630 GQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662



 Score = 66.2 bits (160), Expect = 5e-11
 Identities = 30/60 (50%), Positives = 38/60 (63%), Gaps = 3/60 (5%)

Query: 293 IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEGE 352
           ++  V+  +   RGPPG  GPP   GPPGPPG PGS G+ G+ G  G +G PG KGE G+
Sbjct: 14  LLQVVVLALAQIRGPPGERGPP---GPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGK 70



 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 30/59 (50%), Positives = 34/59 (57%)

Query: 293 IVDTVLAGVPGPRGPPGPPGPPGPRGPPGPPGTPGSQGLAGERGTVGPSGEPGVKGEEG 351
           +V   LA + GP G  GPPGPPGP G PG  G  G  G  G+ G  GP GEPG  G +G
Sbjct: 17  VVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,876,784
Number of Sequences: 37866
Number of extensions: 2531386
Number of successful extensions: 97448
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 808
Number of HSP's successfully gapped in prelim test: 1867
Number of HSP's that attempted gapping in prelim test: 13710
Number of HSP's gapped (non-prelim): 18800
length of query: 439
length of database: 18,247,518
effective HSP length: 105
effective length of query: 334
effective length of database: 14,271,588
effective search space: 4766710392
effective search space used: 4766710392
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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