Guide to the Human Genome
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Search of human proteins with 23238202

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23238202 tumor necrosis factor receptor superfamily, member
19 isoform 1 precursor [Homo sapiens]
         (423 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23238202 tumor necrosis factor receptor superfamily, member 1...   884   0.0  
gi|23238204 tumor necrosis factor receptor superfamily, member 1...   870   0.0  
gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]            189   4e-48
gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]          68   2e-11
gi|23238200 RELT tumor necrosis factor receptor precursor [Homo ...    52   1e-06
gi|21361873 RELT tumor necrosis factor receptor precursor [Homo ...    52   1e-06
gi|23200021 tumor necrosis factor receptor superfamily, member 2...    51   2e-06
gi|23200023 tumor necrosis factor receptor superfamily, member 2...    45   1e-04
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    45   1e-04
gi|89142745 tumor necrosis factor receptor superfamily, member 2...    45   1e-04
gi|4507569 tumor necrosis factor receptor superfamily, member 25...    45   1e-04
gi|23200025 tumor necrosis factor receptor superfamily, member 2...    44   2e-04
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]       43   5e-04
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]       43   5e-04
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             41   0.002
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...    39   0.009
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    38   0.015
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    38   0.020
gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]     38   0.020
gi|38788416 laminin, alpha 1 precursor [Homo sapiens]                  37   0.034
gi|143770880 laminin, beta 4 [Homo sapiens]                            36   0.058
gi|63053515 keratin associated protein 10-3 [Homo sapiens]             36   0.058
gi|63053512 keratin associated protein 10-1 [Homo sapiens]             36   0.075
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  35   0.098
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       35   0.098
gi|167614504 laminin, beta 1 precursor [Homo sapiens]                  35   0.17 
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            35   0.17 
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    35   0.17 
gi|38490571 keratin associated protein 10-7 [Homo sapiens]             35   0.17 
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]       34   0.22 

>gi|23238202 tumor necrosis factor receptor superfamily, member 19
           isoform 1 precursor [Homo sapiens]
          Length = 423

 Score =  884 bits (2284), Expect = 0.0
 Identities = 423/423 (100%), Positives = 423/423 (100%)

Query: 1   MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK 60
           MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK
Sbjct: 1   MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK 60

Query: 61  ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120
           ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG
Sbjct: 61  ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120

Query: 121 FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT 180
           FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT
Sbjct: 121 FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT 180

Query: 181 VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD 240
           VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD
Sbjct: 181 VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD 240

Query: 241 SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI 300
           SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI
Sbjct: 241 SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI 300

Query: 301 CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV 360
           CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV
Sbjct: 301 CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV 360

Query: 361 PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRL 420
           PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRL
Sbjct: 361 PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQVRQRL 420

Query: 421 GSL 423
           GSL
Sbjct: 421 GSL 423


>gi|23238204 tumor necrosis factor receptor superfamily, member 19
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score =  870 bits (2247), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK 60
           MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK
Sbjct: 1   MALKVLLEQEKTFFTLLVLLGYLSCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSK 60

Query: 61  ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120
           ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG
Sbjct: 61  ECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120

Query: 121 FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT 180
           FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT
Sbjct: 121 FYRKTKLVGFQDMECVPCGDPPPPYEPHCASKVNLVKIASTASSPRDTALAAVICSALAT 180

Query: 181 VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD 240
           VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD
Sbjct: 181 VLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSELSCFDRPQLHEYAHRACCQCRRD 240

Query: 241 SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI 300
           SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI
Sbjct: 241 SVQTCGPVRLLPSMCCEEACSPNPATLGCGVHSAASLQARNAGPAGEMVPTFFGSLTQSI 300

Query: 301 CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV 360
           CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV
Sbjct: 301 CGEFSDAWPLMQNPMGGDNISFCDSYPELTGEDIHSLNPELESSTSLDSNSSQDLVGGAV 360

Query: 361 PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQ 415
           PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQ
Sbjct: 361 PVQSHSENFTAATDLSRYNNTLVESASTQDALTMRSQLDQESGAVIHPATQTSLQ 415


>gi|11140823 X-linked ectodysplasin receptor [Homo sapiens]
          Length = 297

 Score =  189 bits (480), Expect = 4e-48
 Identities = 86/196 (43%), Positives = 116/196 (59%)

Query: 33  DCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPC 92
           DC++ E+ D+ G CV C +CGPG ELSK+CG+G G DA C  C   R+K  WG  +C+ C
Sbjct: 2   DCQENEYWDQWGRCVTCQRCGPGQELSKDCGYGEGGDAYCTACPPRRYKSSWGHHRCQSC 61

Query: 93  LDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASK 152
           + CAV+NR QK NC+ATS+A+CGDCLP FYRKT++ G QD EC+PC    P  E  CA +
Sbjct: 62  ITCAVINRVQKVNCTATSNAVCGDCLPRFYRKTRIGGLQDQECIPCTKQTPTSEVQCAFQ 121

Query: 153 VNLVKIASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQ 212
           ++LV+  +    P++  L A++ S L    LA L L  +YCK+ F        L   +  
Sbjct: 122 LSLVEADAPTVPPQEATLVALVSSLLVVFTLAFLGLFFLYCKQFFNRHCQRGGLLQFEAD 181

Query: 213 YNGSELSCFDRPQLHE 228
               E S F  P   E
Sbjct: 182 KTAKEESLFPVPPSKE 197


>gi|11641231 ectodysplasin A receptor precursor [Homo sapiens]
          Length = 448

 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 46/135 (34%), Positives = 63/135 (46%), Gaps = 11/135 (8%)

Query: 16  LLVLLGYLSCKVTCESGDCRQQEFRDRS-GNCVPCNQCGPGMELSKECGFG-YGEDAQCV 73
           L VL+  L C    E  +C + E+ +++ G C  C  CGPG E    CG+G   ED  CV
Sbjct: 13  LPVLVVSLMCSARAEYSNCGENEYYNQTTGLCQECPPCGPGEEPYLSCGYGTKDEDYGCV 72

Query: 74  TCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANC----SATSDAICGDCLPGFYR-KTKLV 128
            C   +F +  G+Q C+   DC     F +A         +DA CG CLPG+Y  + +  
Sbjct: 73  PCPAEKFSKG-GYQICRRHKDC---EGFFRATVLTPGDMENDAECGPCLPGYYMLENRPR 128

Query: 129 GFQDMECVPCGDPPP 143
               M C  C   PP
Sbjct: 129 NIYGMVCYSCLLAPP 143


>gi|23238200 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 51  QCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATS 110
           QC PG E   + G G      C  C    F   WG   C+P   C++  R +     AT 
Sbjct: 31  QCPPGEEPDLDPGQG----TLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATR 86

Query: 111 DAICGDCLPGFYRKTKLVGFQDMECVPCGDPP 142
           D +CGDC PG++      G   + C PC   P
Sbjct: 87  DTLCGDCWPGWFGPW---GVPRVPCQPCSWAP 115


>gi|21361873 RELT tumor necrosis factor receptor precursor [Homo
           sapiens]
          Length = 430

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 30/92 (32%), Positives = 39/92 (42%), Gaps = 7/92 (7%)

Query: 51  QCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSATS 110
           QC PG E   + G G      C  C    F   WG   C+P   C++  R +     AT 
Sbjct: 31  QCPPGEEPDLDPGQG----TLCRPCPPGTFSAAWGSSPCQPHARCSLWRRLEAQVGMATR 86

Query: 111 DAICGDCLPGFYRKTKLVGFQDMECVPCGDPP 142
           D +CGDC PG++      G   + C PC   P
Sbjct: 87  DTLCGDCWPGWFGPW---GVPRVPCQPCSWAP 115


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 33/113 (29%), Positives = 47/113 (41%), Gaps = 14/113 (12%)

Query: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139

Query: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPP 143
           PCLDC  ++R  +  CS   D  CG CLPGFY            CV C  PPP
Sbjct: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFYE-------HGDGCVSCPTPPP 184


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139

Query: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
           PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 43/174 (24%), Positives = 64/174 (36%), Gaps = 39/174 (22%)

Query: 30  ESGDCRQQE---FRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGF 86
           E+  CR QE   +  +   C  C++C PG  +S +C      D  C TC  + + E W +
Sbjct: 39  ENQTCRDQEKEYYEPQHRIC--CSRCPPGTYVSAKCS--RIRDTVCATCAENSYNEHWNY 94

Query: 87  ----QKCKPC------LDCAVVNRFQKANCSATSDAIC-------------GDCLPGFYR 123
               Q C+PC       + A     +K  C       C              DC PG   
Sbjct: 95  LTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEA 154

Query: 124 KTK-LVGFQDMECVPC--------GDPPPPYEPHCASKVNLVKIASTASSPRDT 168
           + K  VG  +  CVPC          P    +PH   +   +  A+  ++  DT
Sbjct: 155 ELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDT 208


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139

Query: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
           PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170


>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139

Query: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
           PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/34 (52%), Positives = 22/34 (64%), Gaps = 1/34 (2%)

Query: 89  CKPCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122
           C+PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 93  CQPCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 125



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 4/52 (7%)

Query: 92  CLDCAVVNRFQKANCSATSDAICGDCLPGFY---RKTKLVGFQDMECVPCGD 140
           C  C   ++    NCSA +D  CG C PG++   + ++ V      C PC D
Sbjct: 48  CRGCPAASQVALENCSAVADTRCG-CKPGWFVECQVSQCVSSSPFYCQPCLD 98


>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
          Length = 1111

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 8/96 (8%)

Query: 29  CESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYG----EDAQCVTCRLHRFKEDW 84
           C SG  R        G C+PCN C  G     + G  Y      D +C  C +  + +  
Sbjct: 396 CASGYKRDSARLGPFGTCIPCN-CQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH 454

Query: 85  GFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120
             + CKPC      N F  +    T + +C +C PG
Sbjct: 455 DPRSCKPC---PCHNGFSCSVMPETEEVVCNNCPPG 487



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 34/127 (26%), Positives = 45/127 (35%), Gaps = 29/127 (22%)

Query: 51  QCGPGMELSKECGFGYGEDAQCVTCR-----LHRFKEDWGFQKCKPCLDCAVVNRFQKAN 105
           QC    EL ++ G G+    +C+ C      +H  K   GF + +    C   N   K +
Sbjct: 36  QCIFDRELHRQTGNGF----RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS 91

Query: 106 CSATSD-------------AICGDCLPGFYRKTKLVGFQDM-------ECVPCGDPPPPY 145
            SA  D             A C  CLPGF+  T     QD        +C P G   P  
Sbjct: 92  LSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD 151

Query: 146 EPHCASK 152
              C  K
Sbjct: 152 AGRCVCK 158


>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
          Length = 1193

 Score = 43.1 bits (100), Expect = 5e-04
 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 8/96 (8%)

Query: 29  CESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYG----EDAQCVTCRLHRFKEDW 84
           C SG  R        G C+PCN C  G     + G  Y      D +C  C +  + +  
Sbjct: 396 CASGYKRDSARLGPFGTCIPCN-CQGGGACDPDTGDCYSGDENPDIECADCPIGFYNDPH 454

Query: 85  GFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPG 120
             + CKPC      N F  +    T + +C +C PG
Sbjct: 455 DPRSCKPC---PCHNGFSCSVMPETEEVVCNNCPPG 487



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 34/127 (26%), Positives = 45/127 (35%), Gaps = 29/127 (22%)

Query: 51  QCGPGMELSKECGFGYGEDAQCVTCR-----LHRFKEDWGFQKCKPCLDCAVVNRFQKAN 105
           QC    EL ++ G G+    +C+ C      +H  K   GF + +    C   N   K +
Sbjct: 36  QCIFDRELHRQTGNGF----RCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPCNCNSKGS 91

Query: 106 CSATSD-------------AICGDCLPGFYRKTKLVGFQDM-------ECVPCGDPPPPY 145
            SA  D             A C  CLPGF+  T     QD        +C P G   P  
Sbjct: 92  LSARCDNSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDPAGIAGPCD 151

Query: 146 EPHCASK 152
              C  K
Sbjct: 152 AGRCVCK 158


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 52/211 (24%), Positives = 79/211 (37%), Gaps = 54/211 (25%)

Query: 34  CRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQK----- 88
           CR++++   S  C  C+ C PG +L  +C      + +C+ C    F + W  +      
Sbjct: 26  CREKQYLINS-QC--CSLCQPGQKLVSDCT--EFTETECLPCGESEFLDTWNRETHCHQH 80

Query: 89  --CKPCLDCAVVNRFQKANCSATSDAICG-------------------DCLPGFYRKTKL 127
             C P L      R Q+   S T D IC                     C PGF  K   
Sbjct: 81  KYCDPNLGL----RVQQKGTSET-DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIA 135

Query: 128 VGFQDMECVPC-----GDPPPPYE-----PHCASKVNLVKIAST-----ASSPRDTALAA 172
            G  D  C PC      +    +E       C +K  +V+ A T        P+D   A 
Sbjct: 136 TGVSDTICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDRLRAL 195

Query: 173 VICSALATVLLALLILCVIYCKRQFMEKKPS 203
           V+   +  +L A+L++ V   K   + KKP+
Sbjct: 196 VVIPIIFGILFAILLVLVFIKK---VAKKPT 223


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score = 38.9 bits (89), Expect = 0.009
 Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 4/92 (4%)

Query: 34  CRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRF-KEDWGFQKCKPC 92
           C Q ++     N + C +C  G  L  +C  G G+D  C  C    F   +   + C  C
Sbjct: 44  CPQGKYIHPQNNSICCTKCHKGTYLYNDCP-GPGQDTDCRECESGSFTASENHLRHCLSC 102

Query: 93  LDC-AVVNRFQKANCSATSDAICGDCLPGFYR 123
             C   + + + ++C+   D +CG C    YR
Sbjct: 103 SKCRKEMGQVEISSCTVDRDTVCG-CRKNQYR 133


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 38.1 bits (87), Expect = 0.015
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 8/91 (8%)

Query: 34  CRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDW-GFQKCKPC 92
           C++ E+   S  C  C +C PG  + + CG   G    C  C    +     G  KC  C
Sbjct: 42  CKEDEYPVGS-EC--CPKCSPGYRVKEACGELTG--TVCEPCPPGTYIAHLNGLSKCLQC 96

Query: 93  LDC-AVVNRFQKANCSATSDAICGDCLPGFY 122
             C   +      NCS T +A+CG C PG +
Sbjct: 97  QMCDPAMGLRASRNCSRTENAVCG-CSPGHF 126



 Score = 29.6 bits (65), Expect = 5.4
 Identities = 21/79 (26%), Positives = 28/79 (35%), Gaps = 3/79 (3%)

Query: 46  CVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKAN 105
           C+ C  C P M L         E+A C  C    F        C  C   A  +  Q+  
Sbjct: 93  CLQCQMCDPAMGLRASRNCSRTENAVC-GCSPGHFCIVQDGDHCAACRAYATSSPGQRVQ 151

Query: 106 CSAT--SDAICGDCLPGFY 122
              T   D +C +C PG +
Sbjct: 152 KGGTESQDTLCQNCPPGTF 170


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 36/152 (23%), Positives = 60/152 (39%), Gaps = 26/152 (17%)

Query: 9   QEKTFFTLLVLLGYLS-CKVTCE-SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGY 66
           + +  F LL+L   L+  +V  + +  C  ++  +  G C  CN+C PG  +S +C    
Sbjct: 7   RRRPLFALLLLCALLARLQVALQIAPPCTSEKHYEHLGRC--CNKCEPGKYMSSKC--TT 62

Query: 67  GEDAQCVTCRLHRFKEDWGFQ-KC---------KPCLDCAVVNRFQKANCSATS------ 110
             D+ C+ C    + + W  + KC         K  +     N      C+ T+      
Sbjct: 63  TSDSVCLPCGPDEYLDSWNEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTAGYHWSQ 122

Query: 111 DAIC----GDCLPGFYRKTKLVGFQDMECVPC 138
           D  C     +C PG   +  L   +D  C PC
Sbjct: 123 DCECCRRNTECAPGLGAQHPLQLNKDTVCKPC 154



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 6/81 (7%)

Query: 43  SGNCVPCN---QCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGF-QKCKPCLDCAVV 98
           S +C  C    +C PG  L  +      +D  C  C    F + +    KC+P  +C  +
Sbjct: 121 SQDCECCRRNTECAPG--LGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFL 178

Query: 99  NRFQKANCSATSDAICGDCLP 119
            +  + + +  SDA+C   LP
Sbjct: 179 GKRVEHHGTEKSDAVCSSSLP 199



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 15/72 (20%)

Query: 114 CGDCLPGFYRKTKLVGFQDMECVPCGDPPPPY------EPHC-------ASKVNLVKIAS 160
           C  C PG Y  +K     D  C+PCG  P  Y      E  C         K  +  +A 
Sbjct: 47  CNKCEPGKYMSSKCTTTSDSVCLPCG--PDEYLDSWNEEDKCLLHKVCDTGKALVAVVAG 104

Query: 161 TASSPRDTALAA 172
            +++PR  A  A
Sbjct: 105 NSTTPRRCACTA 116


>gi|120587029 signal peptide, CUB domain, EGF-like 1 [Homo sapiens]
          Length = 988

 Score = 37.7 bits (86), Expect = 0.020
 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 14/95 (14%)

Query: 49  CNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNRFQKANCSA 108
           C  CGPG     E G       QCV+C    +++  G   C PC     +      N S 
Sbjct: 630 CVACGPGTHFGGELG-------QCVSCMPGTYQDMEGQLSCTPCPSSDGLGLPGARNVSE 682

Query: 109 TSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPP 143
                 G C PGF+      GF+  +  P G   P
Sbjct: 683 CG----GQCSPGFFSAD---GFKPCQACPVGTYQP 710


>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
          Length = 3075

 Score = 37.0 bits (84), Expect = 0.034
 Identities = 28/103 (27%), Positives = 40/103 (38%), Gaps = 11/103 (10%)

Query: 49  CNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQ----KCKPCLDCAVVNRFQKA 104
           CN+C PG                C  C  H   +D  +     K K  L+ A   +F+  
Sbjct: 301 CNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKSLNTA--GQFRGG 358

Query: 105 ----NCSATSDAI-CGDCLPGFYRKTKLVGFQDMECVPCGDPP 142
               NC   +  I C  C+ G+YR  K+  ++D  C PC   P
Sbjct: 359 GVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDP 401


>gi|143770880 laminin, beta 4 [Homo sapiens]
          Length = 1761

 Score = 36.2 bits (82), Expect = 0.058
 Identities = 33/126 (26%), Positives = 47/126 (37%), Gaps = 22/126 (17%)

Query: 48  PCNQ----CGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCL--DCAVVNRF 101
           PCN+    C P       CG G+     C  C    +      Q C+PCL  D    N++
Sbjct: 864 PCNRFAELCDPETGSCFNCG-GFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQY 922

Query: 102 QKANCSA---TSDAIC-----------GDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEP 147
              +C     +SD IC           G+C  GFY   ++ G     C  C +     +P
Sbjct: 923 FAHSCYQNLWSSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCA-CNNNIDVTDP 981

Query: 148 HCASKV 153
              S+V
Sbjct: 982 ESCSRV 987


>gi|63053515 keratin associated protein 10-3 [Homo sapiens]
          Length = 221

 Score = 36.2 bits (82), Expect = 0.058
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 233 ACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGC 269
           +CC         C PV  + S CC+ AC P+P   GC
Sbjct: 35  SCCAPAPCLTLVCTPVSCVSSPCCQAACEPSPCQSGC 71


>gi|63053512 keratin associated protein 10-1 [Homo sapiens]
          Length = 282

 Score = 35.8 bits (81), Expect = 0.075
 Identities = 14/37 (37%), Positives = 18/37 (48%)

Query: 233 ACCQCRRDSVQTCGPVRLLPSMCCEEACSPNPATLGC 269
           +CC         C PV  + S CC+ AC P+P   GC
Sbjct: 35  SCCAPAPCLTLVCTPVSRVSSPCCQAACEPSPCQSGC 71


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 35.4 bits (80), Expect = 0.098
 Identities = 21/77 (27%), Positives = 34/77 (44%), Gaps = 8/77 (10%)

Query: 49  CNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCKPCLDCAVVNR---FQKAN 105
           C++C PG  L + C   +     C  C  H + + W       CL C+ V +   + K  
Sbjct: 41  CDKCPPGTYLKQHCTAKW--KTVCAPCPDHYYTDSW--HTSDECLYCSPVCKELQYVKQE 96

Query: 106 CSATSDAICGDCLPGFY 122
           C+ T + +C +C  G Y
Sbjct: 97  CNRTHNRVC-ECKEGRY 112


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 35.4 bits (80), Expect = 0.098
 Identities = 33/112 (29%), Positives = 44/112 (39%), Gaps = 17/112 (15%)

Query: 16  LLVLLGYL--SCKVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCV 73
           LL+LLG      K  C +G          SG C  C  C  G  +++ CG        C 
Sbjct: 17  LLLLLGVSLGGAKEACPTG------LYTHSGEC--CKACNLGEGVAQPCG---ANQTVCE 65

Query: 74  TCRLHRFKEDW--GFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPGFYR 123
            C       D     + CKPC +C V  +   A C    DA+C  C  G+Y+
Sbjct: 66  PCLDSVTFSDVVSATEPCKPCTEC-VGLQSMSAPCVEADDAVC-RCAYGYYQ 115


>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
          Length = 1786

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 31/124 (25%)

Query: 49  CNQCGPGME-------LSKECGFGYGEDAQC--VTCRLHRFKE------------DWGFQ 87
           CN+C PG            EC      +A C  VT + H F+              WGF 
Sbjct: 803 CNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQCDRCLPGHWGFP 862

Query: 88  KCKPCL------DCAVVNRFQKANC-SATSDAICGDCLPGFYRKTKLVGFQDMECVPCGD 140
            C+PC       DC  V   +  NC   T    C  CL G+Y    ++G  D  C PC  
Sbjct: 863 SCQPCQCNGHADDCDPVTG-ECLNCQDYTMGHNCERCLAGYY-GDPIIGSGD-HCRPCPC 919

Query: 141 PPPP 144
           P  P
Sbjct: 920 PDGP 923


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 34/131 (25%), Positives = 47/131 (35%), Gaps = 36/131 (27%)

Query: 34  CRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQK----- 88
           CR++++   S  C  C+ C PG +L  +C      + +C+ C    F + W  +      
Sbjct: 26  CREKQYLINS-QC--CSLCQPGQKLVSDCT--EFTETECLPCGESEFLDTWNRETHCHQH 80

Query: 89  --CKPCLDCAVVNRFQKANCSATSDAICG-------------------DCLPGFYRKTKL 127
             C P L      R Q+   S T D IC                     C PGF  K   
Sbjct: 81  KYCDPNLGL----RVQQKGTSET-DTICTCEEGWHCTSEACESCVLHRSCSPGFGVKQIA 135

Query: 128 VGFQDMECVPC 138
            G  D  C PC
Sbjct: 136 TGVSDTICEPC 146


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 30/115 (26%), Positives = 50/115 (43%), Gaps = 13/115 (11%)

Query: 17  LVLLGYLSC-------KVTCESGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGED 69
           L+LLG+LS        K +   G  R  +    +G  + C++C  G  +S+ C       
Sbjct: 30  LLLLGFLSTTTAQPEQKASNLIGTYRHVD--RATGQVLTCDKCPAGTYVSEHCT--NTSL 85

Query: 70  AQCVTCRLHRF-KEDWGFQKCKPCLDCAVVNRFQKANCSATSDAICGDCLPGFYR 123
             C +C +  F + + G +KC  C         +K  C+A +D  C  C PG ++
Sbjct: 86  RVCSSCPVGTFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDREC-TCPPGMFQ 139


>gi|38490571 keratin associated protein 10-7 [Homo sapiens]
          Length = 370

 Score = 34.7 bits (78), Expect = 0.17
 Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 10/75 (13%)

Query: 205 SLRSQDIQYN------GSELSCFDRPQLHEYAHRAC----CQCRRDSVQTCGPVRLLPSM 254
           S+ S D+ Y       GS  SC D  Q+ +     C    C         C PV  + S 
Sbjct: 7   SVCSSDLSYGSRVCLPGSCDSCSDSWQVDDCPESCCEPPCCAPAPCLSLVCTPVSYVSSP 66

Query: 255 CCEEACSPNPATLGC 269
           CC   C P+P   GC
Sbjct: 67  CCRVTCEPSPCQSGC 81



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 37/181 (20%), Positives = 55/181 (30%), Gaps = 43/181 (23%)

Query: 106 CSATSDAICGDCLPGFYRKTKLVGFQDMECVPCGDPPPPYEPHCASKV-------NLVKI 158
           C A +  +   C P        V +    C      P P +  C S         +  ++
Sbjct: 46  CCAPAPCLSLVCTP--------VSYVSSPCCRVTCEPSPCQSGCTSSCTPSCCQQSSCQL 97

Query: 159 ASTASSPRDTALAAVICSALATVLLALLILCVIYCKRQFMEKKPSWSLRSQDIQYNGSEL 218
           A  ASSP   A    +C      +    + CV  C              S   Q +    
Sbjct: 98  ACCASSPCQQACCVPVC---CKTVCCKPVYCVPVCSGD----------SSCCQQSSCQSA 144

Query: 219 SCFDRPQLHEYAHRACCQ----------CRRDSVQTCGPVRLLPSMCCEEACSPNPATLG 268
            C   P         CC+          C++ S  +C     + S CC+  C P+P   G
Sbjct: 145 CCTSSPCQQACCVPICCKPVCSGISSSCCQQSSCVSC-----VSSPCCQAVCEPSPCQSG 199

Query: 269 C 269
           C
Sbjct: 200 C 200


>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
          Length = 1816

 Score = 34.3 bits (77), Expect = 0.22
 Identities = 38/134 (28%), Positives = 50/134 (37%), Gaps = 29/134 (21%)

Query: 34  CRQQEFRDRSGNCVPCNQCGPGMELSKEC--GFGYGEDAQCVTCRLHRFKEDWGF----- 86
           C    F   SG CVPC+  G     S EC  G GY    Q  T   H  K   G+     
Sbjct: 67  CNAGFFHTLSGECVPCDCNGN----SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSI 122

Query: 87  ----QKCKPCLDCAVVNRFQKA-NCSATSDAI------------CGDCLPGFYRKTKLVG 129
               Q C+PC  C + +    A +C   + A+            C  C PG+Y    L+G
Sbjct: 123 RGAPQFCQPC-PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIG 181

Query: 130 FQDMECVPCGDPPP 143
               +C   G+  P
Sbjct: 182 STCKKCDCSGNSDP 195


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.133    0.423 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,321,617
Number of Sequences: 37866
Number of extensions: 917104
Number of successful extensions: 3062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 23
Number of HSP's successfully gapped in prelim test: 85
Number of HSP's that attempted gapping in prelim test: 2854
Number of HSP's gapped (non-prelim): 290
length of query: 423
length of database: 18,247,518
effective HSP length: 105
effective length of query: 318
effective length of database: 14,271,588
effective search space: 4538364984
effective search space used: 4538364984
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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