Guide to the Human Genome
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Search of human proteins with 115527070

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor
[Homo sapiens]
         (828 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...  1744   0.0  
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...  1729   0.0  
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...  1727   0.0  
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]       546   e-155
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]           359   5e-99
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      337   4e-92
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     324   2e-88
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   323   5e-88
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   323   5e-88
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   323   5e-88
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   321   2e-87
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   321   2e-87
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   319   6e-87
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   319   6e-87
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   319   6e-87
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         318   2e-86
gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo s...   317   3e-86
gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo s...   317   3e-86
gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo ...   317   3e-86
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     317   4e-86
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   313   5e-85
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   311   1e-84
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      308   2e-83
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...   308   2e-83
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]          303   6e-82
gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]              302   1e-81
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       301   1e-81
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   301   2e-81
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              300   3e-81
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     300   4e-81

>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 1744 bits (4517), Expect = 0.0
 Identities = 828/828 (100%), Positives = 828/828 (100%)

Query: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60
           MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ
Sbjct: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60

Query: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120
           SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK
Sbjct: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120

Query: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180
           NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA
Sbjct: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180

Query: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240
           REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH
Sbjct: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240

Query: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
           EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK
Sbjct: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300

Query: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
           GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA
Sbjct: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360

Query: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
           GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK
Sbjct: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
           GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600
           DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600

Query: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660
           TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV
Sbjct: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660

Query: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720
           GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR
Sbjct: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720

Query: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780
           QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP
Sbjct: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780

Query: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTGLDGAVLC 828
           QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTGLDGAVLC
Sbjct: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTGLDGAVLC 828


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 1729 bits (4477), Expect = 0.0
 Identities = 822/825 (99%), Positives = 822/825 (99%)

Query: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60
           MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ
Sbjct: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60

Query: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120
           SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK
Sbjct: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120

Query: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180
           NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA
Sbjct: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180

Query: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240
           REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH
Sbjct: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240

Query: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
           EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK
Sbjct: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300

Query: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
           GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA
Sbjct: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360

Query: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
           GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK
Sbjct: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
           GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600
           DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600

Query: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660
           TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV
Sbjct: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660

Query: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720
           GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR
Sbjct: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720

Query: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780
           QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP
Sbjct: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780

Query: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTGLDGA 825
           QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQT L  A
Sbjct: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQTELSVA 825



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 44/174 (25%), Positives = 80/174 (45%), Gaps = 26/174 (14%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEA 673
            +D+VF++D SE +G  NF   + FV  V  RL  +A+        RV ++Q+   G    
Sbjct: 832  VDIVFLLDGSERLGEQNFHKARRFVEQVARRL-TLARRDDDPLNARVALLQFGGPG---E 887

Query: 674  IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESR---RQKTRVFAVVI 730
             Q+      +L++  EA++  +++   +   + +  A + +++  R   R+   +  V +
Sbjct: 888  QQVAFPLSHNLTAIHEALETTQYLNSFSHVGAGVVHAINAIVRSPRGGARRHAELSFVFL 947

Query: 731  TDG----------RHDPRDDD-----LNLRALCDRDVTVTAIGIGD---MFHEK 766
            TDG           H  R  +     L L +  D DV +T + +GD   +FHEK
Sbjct: 948  TDGVTGNDSLHESAHSMRKQNVVPTVLALGSDVDMDV-LTTLSLGDRAAVFHEK 1000


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 1727 bits (4474), Expect = 0.0
 Identities = 820/820 (100%), Positives = 820/820 (100%)

Query: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60
           MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ
Sbjct: 1   MLQGTCSVLLLWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQ 60

Query: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120
           SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK
Sbjct: 61  SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFSPPGSDRASFIK 120

Query: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180
           NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA
Sbjct: 121 NLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERA 180

Query: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240
           REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH
Sbjct: 181 REEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKH 240

Query: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
           EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK
Sbjct: 241 EAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300

Query: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
           GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA
Sbjct: 301 GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360

Query: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
           GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK
Sbjct: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL
Sbjct: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
           GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG
Sbjct: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540

Query: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600
           DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE
Sbjct: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRE 600

Query: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660
           TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV
Sbjct: 601 TCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRV 660

Query: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720
           GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR
Sbjct: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRR 720

Query: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780
           QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP
Sbjct: 721 QKTRVFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDKP 780

Query: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQT 820
           QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQT
Sbjct: 781 QQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLPCQT 820


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score =  546 bits (1408), Expect = e-155
 Identities = 320/806 (39%), Positives = 446/806 (55%), Gaps = 47/806 (5%)

Query: 42  DCPIHVYFVLDTSESVTMQ-SPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRYGGLH 100
           DCP+ ++FVLDTSESV ++  P   L+  +K F  +FI  L++ +Y     L W  G LH
Sbjct: 33  DCPVDLFFVLDTSESVALRLKPYGALVDKVKSFTKRFIDNLRDRYYRCDRNLVWNAGALH 92

Query: 101 FSDQVEVFSP----PGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVH- 155
           +SD+VE+       PG  R +   ++  +  F +GT+TDCA+    EQ+    S    + 
Sbjct: 93  YSDEVEIIQGLTRMPGG-RDALKSSVDAVKYFGKGTYTDCAIKKGLEQLLVGGSHLKENK 151

Query: 156 FAVVITDGHVTGS---PCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELY 212
           + +V+TDGH       PCGG++     A+  G+++F+VA   +  E  L  IA T H   
Sbjct: 152 YLIVVTDGHPLEGYKEPCGGLEDAVNEAKHLGVKVFSVAITPDHLEPRLSIIA-TDHTYR 210

Query: 213 RNDYAT---MLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGA 269
           RN  A       D+ E    TI+ I+ ++K+     C    C    GP G +G  G +G 
Sbjct: 211 RNFTAADWGQSRDAEEAISQTIDTIVDMIKNNVEQVCCSFECQPARGPPGLRGDPGFEGE 270

Query: 270 KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329
           +G  G PGE G+ G  G PG  GP+G+ G KG  G +GEKG  G  G KG  G  G +G 
Sbjct: 271 RGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGV 330

Query: 330 DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389
           DG KG++G  G PGCKG PG  G  G PG  G PG  G +G KG+PG  G  G PG  G 
Sbjct: 331 DGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGP 390

Query: 390 KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449
            G +G  G  G PG  G  G +G PGP G  GE G  G+ G +G+PG+ GP+G+ G+ GP
Sbjct: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450

Query: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509
           +G +G  G VG  G  G+ G  GP+G +G  G PG +G+RG PG AGP GD G  G +G+
Sbjct: 451 QGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGE 510

Query: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG-------P 562
            G  G    G  G PG  G PG RG  G     G KG PG KG++GE  DPG       P
Sbjct: 511 DGPAG---NGTEGFPGFPGYPGNRGAPGIN---GTKGYPGLKGDEGEAGDPGDDNNDIAP 564

Query: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGALDVVFVIDS 622
            G  G +G RG  GP+G PG  G PG  EC+++  + + C CC+C  +CG +D++FV+DS
Sbjct: 565 RGVKGAKGYRGPEGPQGPPGHQGPPGPDECEILDIIMKMCSCCEC--KCGPIDLLFVLDS 622

Query: 623 SESIGYTNFTLEKNFVINVVNRLGAIAKDP--KSETG-TRVGVVQYSHEGTFEAIQLDDE 679
           SESIG  NF + K+FV+ V++RL   ++D   K E G +  GVVQYSH    E + L   
Sbjct: 623 SESIGLQNFEIAKDFVVKVIDRL---SRDELVKFEPGQSYAGVVQYSHSQMQEHVSLRSP 679

Query: 680 RIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRD 739
            I ++   KEA+K+L+W+AGGT+T  AL++  D+L+  S   +    A+VITDGR D + 
Sbjct: 680 SIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPSPNNR---IALVITDGRSDTQR 736

Query: 740 DDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD--KPQQVR-NMTL----FSDL 792
           D   L  LC   + V ++GI D+F     S+ L  I+C    P Q R  ++L    +++L
Sbjct: 737 DTTPLNVLCSPGIQVVSVGIKDVFDFIPGSDQLNVISCQGLAPSQGRPGLSLVKENYAEL 796

Query: 793 VAEKFIDDMEDVLCPDPQIVCPDLPC 818
           + + F+ ++   +C D +  CPD  C
Sbjct: 797 LEDAFLKNVTAQICIDKK--CPDYTC 820



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 32/120 (26%), Positives = 54/120 (45%), Gaps = 4/120 (3%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNR-LGAIAKDPKSETGTRVGVVQYSHEGTFEA 673
           D+  ++D S S+G  NF   K F   +  R L A   DP  +   RV VVQYS  G    
Sbjct: 829 DITILLDGSASVGSHNFDTTKRFAKRLAERFLTAGRTDPAHD--VRVAVVQYSGTGQQRP 886

Query: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVITDG 733
            +   + + + ++   AV  +++I   T    AL +   R  +E+     +   ++ +DG
Sbjct: 887 ERASLQFLQNYTALASAVDAMDFINDATDVNDALGYV-TRFYREASSGAAKKRLLLFSDG 945



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 14/134 (10%)

Query: 36  NCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM-KQFVPQFISQL-QNEFYLDQVALS 93
           +C E    PI + FVLD+SES+ +Q+      F + K FV + I +L ++E    +   S
Sbjct: 605 SCCECKCGPIDLLFVLDSSESIGLQN------FEIAKDFVVKVIDRLSRDELVKFEPGQS 658

Query: 94  W----RYGGLHFSDQVEVFSPPGSDRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDR 149
           +    +Y      + V + SP   +     + ++ +     GTFT  AL    +Q+    
Sbjct: 659 YAGVVQYSHSQMQEHVSLRSPSIRNVQELKEAIKSLQWMAGGTFTGEALQYTRDQLLPPS 718

Query: 150 SKGTVHFAVVITDG 163
               +  A+VITDG
Sbjct: 719 PNNRI--ALVITDG 730


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score =  359 bits (922), Expect = 5e-99
 Identities = 239/580 (41%), Positives = 311/580 (53%), Gaps = 61/580 (10%)

Query: 256 GPSGPKGYRGQ--KGAKGNMGEPGEPGQKG-----RQGDPGIEGPIGFPGPKG-----VP 303
           GP+GP+G +G   KG KG++G  G  G  G      QG+ GI+GPIG PGP+G     +P
Sbjct: 418 GPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLP 477

Query: 304 GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
           G KGE G+ G  G +G  G+    G  G KG+ G IG PG  G PG  G  G  GEAG P
Sbjct: 478 GSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLP 533

Query: 364 GERGDQG--GKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPG-----P 416
           G RG +G  GKG PG  G  G  G  G +G +G  G  G  G PG+ G  G PG     P
Sbjct: 534 GARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGP 593

Query: 417 RGPKGEPGRRGDPGTKGSPGSD--GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
            GPKG+ G  G PG KG PG    GPKG +G  GP G  GL G+ G  G  G RGLPGP 
Sbjct: 594 PGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPP 652

Query: 475 GPQGA-----LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGE--- 526
           GP G       G  G+ G RG PG +GPRG  G  GPKGD G+ G   PGP G PG    
Sbjct: 653 GPMGLRGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGL--PGPPGPPGYGSQ 709

Query: 527 --KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPP 584
             KGE GP+G  G +G  G  G PG+KGE GE  D G  G+ G  G  G PG +G  GP 
Sbjct: 710 GIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768

Query: 585 GDPGLTECDVMTYVRETCGC-CDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVN 643
           GD GLT+ +++  + E CGC   C++    L++VFVIDSSES+G  NF + KNFV  + +
Sbjct: 769 GDLGLTKEEIIKLITEICGCGPKCKET--PLELVFVIDSSESVGPENFQIIKNFVKTMAD 826

Query: 644 RLGAIAKDPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWT 703
           R   +A D  +    R+G++ YSH+    A   + ++  S   FK AV N++++  GT+T
Sbjct: 827 R---VALDLAT---ARIGIINYSHKVEKVA---NLKQFSSKDDFKLAVDNMQYLGEGTYT 877

Query: 704 PSALKFAYDRLIKESRRQKTRVFAVVITDGRHDPRDDDL---NLRALCDRDVTVTAIGI- 759
            +AL+ A D    E  R   +  A+VITDG+ D RD +     ++   D +V +  IG+ 
Sbjct: 878 ATALQAANDMF--EDARPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVV 935

Query: 760 ---GDMFHEKHESENLYSIACDKPQQVRNMTLFSDLVAEK 796
                 F   H+  NL +   +   Q  +     D + +K
Sbjct: 936 KKNDPNFEIFHKEMNLIATDPEHVYQFDDFFTLQDTLKQK 975



 Score =  312 bits (799), Expect = 9e-85
 Identities = 223/632 (35%), Positives = 303/632 (47%), Gaps = 104/632 (16%)

Query: 43  CPIHVYFVLDTSESVTMQSPTDILLFHMKQFVPQFISQLQNEFYLDQVALSWRY----GG 98
           C I + F++D+SES      + I LF  ++    F+  L ++ +      S  Y      
Sbjct: 45  CFIDIVFIVDSSES------SKIALFDKQK---DFVDSLSDKIFQLTPGRSLEYDIKLAA 95

Query: 99  LHFSDQVEVFSPPGS--DRASFIKNLQGISSFRRGTFTDCALANMTEQIRQDRSKGTVHF 156
           L FS  V++  P  S  D  +F + ++ ++   +GTF+  A++N T  ++++  K  V  
Sbjct: 96  LQFSSSVQIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKV 155

Query: 157 AVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIASTPHELYRNDY 216
            +++TDG +       ++  +E AR  GI    +A +  + E  LR I+        ++ 
Sbjct: 156 VLLMTDG-IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSS----SEP 210

Query: 217 ATMLPDSTEID--QDTINRIIKVMKHEAYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMG 274
             +L D T +D  QD ++ + +        EC K      PG  GP G  G  G KG  G
Sbjct: 211 TLLLSDPTLVDKIQDRLDILFEKKCERKICECEKGD----PGDPGPPGTHGNPGIKGERG 266

Query: 275 EPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKG 334
             G PG   ++G+ G  GP G PG KG  G +GE G+ G  G KG+PG  G  G  G +G
Sbjct: 267 PKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQG 325

Query: 335 KLGRIGPPGCKGDPGNRGPDGYPGEAGSPG-----ERGDQGGKGDPGRPGRRGP-----P 384
             G  G PG KG  GN+G  G PG  GSPG     ++G +G +G  GRPG  GP     P
Sbjct: 326 ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEP 385

Query: 385 GEIGAKGSKGYQGNSGAPGS--PGVKGAKGGPGPRGP--------KGEPGRRGDPGTKG- 433
           G+ G +G +G  G  G PG   PG KG KG  GP GP        KGE G  G  G +G 
Sbjct: 386 GQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGP 445

Query: 434 -------SPGSDGPKGEKGDPGPEGPRGLA-----GEVGNKGAKGDRG-----LPGPRGP 476
                  S G  G +G  G PGP+GP G       GEVG  G  G RG     + GP+G 
Sbjct: 446 MGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE 505

Query: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGE------- 529
            G++G PG+ G  G+ G AG +G++G PG +G  G PG   PGP+G  G+KG        
Sbjct: 506 PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR 565

Query: 530 --PGPRGPEGGRGDFG--------LKGEPGRKGEKGEPADPGPPGEP-----------GP 568
             PGP GP+G  G  G        + G PG KG++G P  PG  GEP           GP
Sbjct: 566 GLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGP 625

Query: 569 RGP-----------RGVPGPEGEPGPPGDPGL 589
           RGP            GVPGP G PGPPG  GL
Sbjct: 626 RGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGL 657



 Score =  160 bits (405), Expect = 5e-39
 Identities = 87/191 (45%), Positives = 108/191 (56%), Gaps = 13/191 (6%)

Query: 408 KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSD-----GPKGEKGDPGPEGPRGLAGEVGNK 462
           KG  G PGP G  G PG +G+ G KG+PG+      G +G  G PG +G +G  GE G  
Sbjct: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303

Query: 463 GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKG---DPGRPGFSYPG 519
           G KGD+G PGP GP+G  G  G  G  GDPG  G +G+ G+PGP G    PG PG    G
Sbjct: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQG 363

Query: 520 PRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEG 579
            +G  G++G PG  GP G     G  G+PG +G +G P + G PGE  P GP+G  G EG
Sbjct: 364 IKGERGQEGRPGAPGPIG----VGEPGQPGPRGPEGVPGERGLPGEGFP-GPKGEKGSEG 418

Query: 580 EPGPPGDPGLT 590
             GP G  GL+
Sbjct: 419 PTGPQGLQGLS 429



 Score =  123 bits (308), Expect = 8e-28
 Identities = 71/150 (47%), Positives = 83/150 (55%), Gaps = 9/150 (6%)

Query: 443 EKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSG 502
           EKGDPG  GP G  G  G KG +G +G PG    +G  GE G  G  G  GD G RG+ G
Sbjct: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECG 301

Query: 503 QPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG 561
           +PG KGD G PG +   GPRG  G  G PG  GP+G +G+   KGEPG  G  G P  PG
Sbjct: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN---KGEPGPPGPYGSPGAPG 358

Query: 562 PPGEPGPRGPRGVPGPEGEPGPPGDPGLTE 591
                G +G +G  G EG PG PG  G+ E
Sbjct: 359 I----GQQGIKGERGQEGRPGAPGPIGVGE 384



 Score =  107 bits (268), Expect = 3e-23
 Identities = 65/143 (45%), Positives = 78/143 (54%), Gaps = 10/143 (6%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  GP+G  G  G  G  G     G  G +G+PG+ GP G  GP+GV G +G KG+ G 
Sbjct: 640 PGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQ 694

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            G  G PG  G  G+ G KG+ G  G PG KG  G+    G PG+ G  GERGD G KGD
Sbjct: 695 KGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGD 749

Query: 375 PGRPGRRGPPGEIGAKGSKGYQG 397
            G  G  G PG+ G +G KG  G
Sbjct: 750 KGEIGEPGSPGKQGLQGPKGDLG 772



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 36/131 (27%), Positives = 71/131 (54%), Gaps = 8/131 (6%)

Query: 614 LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFEA 673
           +D+VF++DSSES     F  +K+FV ++ +++  +      E   ++  +Q+S      +
Sbjct: 47  IDIVFIVDSSESSKIALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFS-----SS 101

Query: 674 IQLDD--ERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVVIT 731
           +Q+D        L +FK+ VK++  I  GT++  A+  A   L +E R+   +V  +++T
Sbjct: 102 VQIDPPFSSWKDLQTFKQKVKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKV-VLLMT 160

Query: 732 DGRHDPRDDDL 742
           DG   P++ D+
Sbjct: 161 DGIDHPKNPDV 171



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 27/62 (43%), Positives = 36/62 (58%), Gaps = 2/62 (3%)

Query: 254 IPGPSGPKGYRGQKGAKGN--MGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           I G  GP+G+ G KG  G+   G+ GE G++G  G  G +G IG PG  G  G +G KG+
Sbjct: 711 IKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770

Query: 312 FG 313
            G
Sbjct: 771 LG 772



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 60/274 (21%), Positives = 109/274 (39%), Gaps = 32/274 (11%)

Query: 11   LWGILGAIQAQQQEVISPDTTERNNNCPEKTDCPIHVYFVLDTSESVTMQSPTDILLFHM 70
            L G  G +   ++E+I    TE     P+  + P+ + FV+D+SESV  ++         
Sbjct: 764  LQGPKGDLGLTKEEIIKL-ITEICGCGPKCKETPLELVFVIDSSESVGPEN--------- 813

Query: 71   KQFVPQFISQLQNEFYLDQVALSWRYGGLHFSDQVEVFS--PPGSDRASFIKNLQGISSF 128
             Q +  F+  + +   LD      R G +++S +VE  +     S +  F   +  +   
Sbjct: 814  FQIIKNFVKTMADRVALDLATA--RIGIINYSHKVEKVANLKQFSSKDDFKLAVDNMQYL 871

Query: 129  RRGTFTDCALANMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLF 188
              GT+T  AL    +   +D   G    A+VITDG         +    + A +  + +F
Sbjct: 872  GEGTYTATALQAANDMF-EDARPGVKKVALVITDGQTDSRDKEKLTEVVKNASDTNVEIF 930

Query: 189  AVA------PNQNLKEQGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEA 242
             +       PN  +  + +  IA+ P  +Y+ D           D  T+   +K    + 
Sbjct: 931  VIGVVKKNDPNFEIFHKEMNLIATDPEHVYQFD-----------DFFTLQDTLKQKLFQK 979

Query: 243  YGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEP 276
              E +    ++I G S P+   G  G + +   P
Sbjct: 980  ICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTP 1013


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  337 bits (863), Expect = 4e-92
 Identities = 179/362 (49%), Positives = 208/362 (57%), Gaps = 32/362 (8%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGP------KGVPGFKGE 308
            PGP+GP+G  GQ G  G  GEPG  GQ+G  G  G EGP GFPGP      +G+PG  GE
Sbjct: 1179 PGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGC---------KGDPGNRGPDGYPGE 359
            KGE G  G+ G PG  G  G  G  G  G  GPPG          KG+PG  G  G PGE
Sbjct: 1239 KGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298

Query: 360  AGSPGERGDQGGKGDPGR------PGRRGPPGEIGAKGSKG---YQGNSGAPGSPGVKGA 410
             G PG +G++G KG+ G       PG +GPPG+ G KGS G   + G+ G PG PG  G 
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358

Query: 411  KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G PG +G  GEPG+ G PG  G PG  GP G++G PGP GP G  GE G KG  G  G 
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGP 1418

Query: 471  PG---PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEK 527
            PG   P GPQGA G+PG  G RG PG  G +G  G PGP G PG  G     P G PG K
Sbjct: 1419 PGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMG-----PPGLPGLK 1473

Query: 528  GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            G+ GP+G +G  G  GL G PG +GEKG+   PGP G  GP+G +G+ GP G  GPPG P
Sbjct: 1474 GDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPP 1533

Query: 588  GL 589
            GL
Sbjct: 1534 GL 1535



 Score =  325 bits (832), Expect = 1e-88
 Identities = 176/376 (46%), Positives = 201/376 (53%), Gaps = 43/376 (11%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA- 314
            GP GP G+ G KG  G  G+ G PG  G++G+ G +G  G PGP GV G +G  GE G  
Sbjct: 952  GPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011

Query: 315  -----------DGRKGAPGLAGKNGTDGQKGKLG---RIGPPGCKGDP------------ 348
                        G +G PGLAGK GT G  G  G   + GPPG +G P            
Sbjct: 1012 GERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL 1071

Query: 349  ---GNRGPDGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAP 402
               GN GP G PG AGSPGERG  G  G    PGRPG +GPPG  G KG+ G +G  G  
Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1131

Query: 403  GSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G  G++G  G PGP GP G PG  GD G  G PG  G KG+KG+ GP GP G  G +G  
Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191

Query: 463  GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF------- 515
            G  G  G PGPRG QG  G+ G +G RG PG  GP G  G PGP G+ G  G        
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPP 1251

Query: 516  SYPGPRGAPGEKGEPGPRGPEGGRGD---FGLKGEPGRKGEKGEPADPGPPGEPGPRGPR 572
              PGPRG  G  G  GP+GP GG G+    G KGEPG  GE G P + GPPG  G RG +
Sbjct: 1252 GPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311

Query: 573  GVPGPEGEPGPPGDPG 588
            G  GP G  GPPG  G
Sbjct: 1312 GESGPSGAAGPPGPKG 1327



 Score =  315 bits (806), Expect = 1e-85
 Identities = 169/356 (47%), Positives = 196/356 (55%), Gaps = 28/356 (7%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV---PGFKGEKGE 311
            PGP GP G  G+KGA      PGE G +G  G  G++GP+G PGP G    PG  G+KGE
Sbjct: 1107 PGPQGPPGPAGEKGA------PGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G  G+KG+ G  G+ G  G  G  G IG PG  G  G  GP G  G  G  G+ G +G 
Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGF 1220

Query: 372  KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
             G PG  G +G PG  G KG  G  G  G PG PG +G  G PG  GP+G PG  G+PG 
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA 1280

Query: 432  ---KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP---QGALGEPGK 485
               KG PG  G  G  G+ GP GP+G  GE G  G  G  G PGP+GP    G  G PG 
Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGP 1340

Query: 486  QGSRGD---PGDAGPRGDSGQPGPKGDPGRPG-------FSYPGPRGAPGEKGEPGPRGP 535
             G  GD   PG+ GP G  G PG KGD G PG          PGP G PG++G PGP GP
Sbjct: 1341 VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP 1400

Query: 536  EGGRGDFGLKGEPGRKGEKGEPADPGP---PGEPGPRGPRGVPGPEGEPGPPGDPG 588
            EG +G+ G KGE G +G  G+    GP   PG+PGP G RG+PGP GE G PG PG
Sbjct: 1401 EGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG 1456



 Score =  311 bits (796), Expect = 2e-84
 Identities = 173/361 (47%), Positives = 201/361 (55%), Gaps = 31/361 (8%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
            G  GP+G  G+ G KGN G  G  G  G +G  G +GP GFPGPKG PG  G+ G  G  
Sbjct: 919  GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978

Query: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---PDGYPGEAGSPGERGDQGGK 372
            G++G  G  GK G  G  G +G  GP G  G  G RG   P G PGE G PG  G +G K
Sbjct: 979  GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038

Query: 373  GDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD---- 428
            GDPG  G  G  G  G +G  G +G  G  G+ G+KG +G PGP GP G PG RG     
Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAA 1098

Query: 429  -----PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP------- 476
                 PG  G  G  GP GEKG PG +GP+G AG     G +G  GLPGP GP       
Sbjct: 1099 GPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR---DGLQGPVGLPGPAGPVGPPGED 1155

Query: 477  --QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAP---GEKGEP 530
              +G +GEPG++GS+GD G+ GP G +G  GP G PG  G    PGPRG     G+KG+ 
Sbjct: 1156 GDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDE 1215

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPAD---PGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            GPRG  G  G  GL+G PG  GEKGE  D    GPPG PGPRGP G PG +G  GPPG  
Sbjct: 1216 GPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGI 1275

Query: 588  G 588
            G
Sbjct: 1276 G 1276



 Score =  310 bits (795), Expect = 3e-84
 Identities = 167/348 (47%), Positives = 196/348 (56%), Gaps = 20/348 (5%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            GP G  G  G  GA G  G PG+   PG+KG QG PG +GPIG+PGP+GV G  G +G  
Sbjct: 745  GPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLK 804

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP------DGYPGEAGSPGER 366
            G  G KG  G  G  G  G KG  G IGPPG +G+ G  GP      +G PG  G PGE+
Sbjct: 805  GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864

Query: 367  GDQGGKGDPGRPGRRGPPGEI---GAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
            G  G  G PG PGR+GP G I   G  G+ G +G  G PG PG +G +G  GPRG +G  
Sbjct: 865  GKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPR 924

Query: 424  GRRGDPGTKGSPGSD---GPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
            G  G PG KG+ G D   GP GE+G  GP+GP G  G  G  G  G  GLPG  G +G  
Sbjct: 925  GITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 481  GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
            G  GK G  G PG  GP+G +G+ GP G+ G     +PGP G PGE+G PG  G EG +G
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERG-----HPGPPGPPGEQGLPGLAGKEGTKG 1039

Query: 541  DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            D G  G PG+ G  G    PG  G PGP G  G+ G EG PGPPG  G
Sbjct: 1040 DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087



 Score =  307 bits (786), Expect = 3e-83
 Identities = 176/377 (46%), Positives = 198/377 (52%), Gaps = 44/377 (11%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
            PGP G  G  G KG  G  G+PG    PG+KG+ G PG+ G  G  GPKG  GF G  G 
Sbjct: 834  PGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGA 893

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G  G +G PG  G  G  G  G  G  GP G  G PG +G  G  G AG PGERG  G 
Sbjct: 894  NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953

Query: 372  ---------KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE 422
                     KG PG PG+ G PG  G +G  G+QG +G PG PGV G +G  G  GP GE
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 423  ---PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGA 479
               PG  G PG +G PG  G +G KGDPGP G  G  G  G +G  GDRGLPGP G  G 
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 480  LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEG-- 537
             G  G  G  G  G  G RG +G  GP G PGRPG    GP G  GEKG PG +GP+G  
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQ--GPPGPAGEKGAPGEKGPQGPA 1131

Query: 538  GR----------------------GDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVP 575
            GR                      GD G  GEPG+KG KG+  + GPPG  GP+GP G P
Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191

Query: 576  GP---EGEPGPPGDPGL 589
            GP   +GEPGP G  GL
Sbjct: 1192 GPSGADGEPGPRGQQGL 1208



 Score =  306 bits (784), Expect = 5e-83
 Identities = 167/366 (45%), Positives = 194/366 (53%), Gaps = 31/366 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG---------PKGVPG 304
            +PG  GP G RG  G +G  G  G  G KG +G PG  GP G PG         P G+PG
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
              G +G  G  G KGAPG  G  G  G+ G  G +G PG  G  G  G DG  GE G PG
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 365  ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG------ 418
            ++G +G KG+ G PG  GP G IG  G  G  G  G  G  G+ G KG  GPRG      
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPG 1225

Query: 419  ---------PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRG 469
                     P GE G  GD G  G PG  GP+G  G PG +GP+G  G +GN GA G++G
Sbjct: 1226 PVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKG 1285

Query: 470  LPGPRGPQGALGE---PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPG 525
             PG  G  G  GE   PG +G RG+ G++GP G +G PGPKG PG  G    PGP G PG
Sbjct: 1286 EPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPG 1345

Query: 526  E---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
            +    GEPGP G +G  GD G  GEPG+ G  G   +PGP G PG RGP G  GPEG  G
Sbjct: 1346 DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG 1405

Query: 583  PPGDPG 588
              G  G
Sbjct: 1406 EKGAKG 1411



 Score =  305 bits (782), Expect = 9e-83
 Identities = 172/380 (45%), Positives = 202/380 (53%), Gaps = 43/380 (11%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP+GP G  G+ G KG +GEPG+ G KG +G+ G  GP G  GP G PG  G  GE G
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G++G  G  G  G  G  G  G +G  G  G PG +G  G  G+ G PG  G +G  G
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR------RG 427
             PG  G +GPPG IG  G+ G +G  G  G PG+ G  G PGP+G +GE G        G
Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG 1321

Query: 428  DPGTKGSPGSDGPKGE------KGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALG 481
             PG KG PG DGPKG        GDPGP G  G AG+ G  G KGD G PG  G  G  G
Sbjct: 1322 PPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTG 1381

Query: 482  EPGKQ---GSRGDPGDAGPRGDSGQP------------------GPKGDPGRPG----FS 516
            EPG     G RG PG AGP G  G+                   GP+G PG+PG      
Sbjct: 1382 EPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRG 1441

Query: 517  YPGP---RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGPRG 570
             PGP   +G PG  G  GP GP G  G  GLKG+ G KGEKG P      GPPGE G +G
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKG 1501

Query: 571  PRGVPGPEGEPGPPGDPGLT 590
             RG+PGP+G  GP G+ G+T
Sbjct: 1502 DRGLPGPQGSSGPKGEQGIT 1521



 Score =  301 bits (772), Expect = 1e-81
 Identities = 162/340 (47%), Positives = 188/340 (55%), Gaps = 11/340 (3%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP+G  G  G  G +G  G+ G PG  G  G  G EGP G PGP G PG +G  G  G 
Sbjct: 1041 PGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGP 1100

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G PG  G  G  G+KG  G  GP G  G  G +GP G PG AG  G  G+ G KG+
Sbjct: 1101 IGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGE 1160

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G PG++G  G+ G +G  G  G  G  G PG  GA G PGPRG +G  G++GD G +G 
Sbjct: 1161 IGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGF 1220

Query: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494
            PG  GP G +G PGP G +G  G+VG  G  G    PGPRGP GA G  G QG  G  G+
Sbjct: 1221 PGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP---PGPRGPSGAPGADGPQGPPGGIGN 1277

Query: 495  AGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554
             G  G+ G+PG  G+PG PG    GP G  GE+GE G  GP G  G  G KG PG  G K
Sbjct: 1278 PGAVGEKGEPGEAGEPGLPGEG--GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPK 1335

Query: 555  GE------PADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G       P DPGPPGEPGP G  G PG +G+ G PG  G
Sbjct: 1336 GSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTG 1375



 Score =  300 bits (767), Expect = 5e-81
 Identities = 179/425 (42%), Positives = 217/425 (51%), Gaps = 91/425 (21%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGE---------------PGQKGRQGDPGIEGPIGFPG- 298
            PGP+G  G RG+ G+ G  G PG+               PG+KG +GDPG  GP G PG 
Sbjct: 600  PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 299  -----------PKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGP------ 341
                       P+G+PG  G +G  G  G  G PG  G  G DGQ G  G +GP      
Sbjct: 660  DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719

Query: 342  PGCKGDPGNRGPDGYPGEAGSPGERGD---------QGGKGDPGRPGRRGPPGEIGAKGS 392
            PG +G+PG +G  G  G  G PGE+G           G  G PG PG+ GPPGE G +G 
Sbjct: 720  PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGP 779

Query: 393  KGYQGNSGAPGSPGVKGAKGGPGPRGPKGE------PGRRGDPGTKGSPGSDGPKGEKGD 446
             G QG  G PG  GVKGA G  G +G KGE      PG +GD G KG  G  GP G +G+
Sbjct: 780  PGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGE 839

Query: 447  PGPEGPRGLA------------GEVGNKGAKGDRGLPGPRGPQGALGEP------GKQGS 488
             GPEGP+G              GE G  G  G  G PG +GP+G++G P      G++G 
Sbjct: 840  DGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGG 899

Query: 489  RGDP---------------GDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE 529
            RG P               G+ GPRG +G+PGPKG+ G  G + P    GP G  G  G 
Sbjct: 900  RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959

Query: 530  PGPRGPEGGRGDFGLKGEPGRKGE---KGEPADPGPPGEPGPRGPRGVPGPEGE---PGP 583
            PGP+GP G  G  GL G PG++GE   +G+   PGPPG  GP+GP G  GP GE   PGP
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019

Query: 584  PGDPG 588
            PG PG
Sbjct: 1020 PGPPG 1024



 Score =  298 bits (763), Expect = 1e-80
 Identities = 165/377 (43%), Positives = 196/377 (51%), Gaps = 43/377 (11%)

Query: 255  PGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
            PGP GP GY   RG KGA G  G  G  G+KG  G PG +G +G  G +G  G  G +GE
Sbjct: 780  PGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGE 839

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G +G KG  G  G  G  G  G+ G++G PG  G PG +GP G  G  G PG  G++GG
Sbjct: 840  DGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGG 899

Query: 372  KGDPGRP------------GRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG------ 413
            +G PG+P            G RGP G  G  G KG  G  G  G PG +G  G       
Sbjct: 900  RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959

Query: 414  PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGL 470
            PGP+GP G PG+ G PG  G  G  G +G+ G PGP    GP+G  GE G  G +G  G 
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----------GP 520
            PGP G QG  G  GK+G++GDPG AG  G  G PG +G PG  G   P          GP
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP 1079

Query: 521  RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR-------- 572
             G PG  G PG RGP G  G  G+ G PG +G  G   + G PGE GP+GP         
Sbjct: 1080 PGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGP 1139

Query: 573  -GVPGPEGEPGPPGDPG 588
             G+PGP G  GPPG+ G
Sbjct: 1140 VGLPGPAGPVGPPGEDG 1156



 Score =  293 bits (751), Expect = 3e-79
 Identities = 181/423 (42%), Positives = 205/423 (48%), Gaps = 88/423 (20%)

Query: 252 LEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           L + GP+GP G  G+ G    +G PG  G KG  GD G +GP G  GP G  G  G +G 
Sbjct: 555 LALRGPAGPMGLTGRPGP---VGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGR 611

Query: 312 FGADGRKGAPG------------LAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE 359
            G+DG +G PG            LAG  G  G +G  G  GPPG  GD G RG DG  G 
Sbjct: 612 AGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGP 671

Query: 360 AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKG---------------YQGNSGAPGS 404
            G PGE G +G  G  G PG  GPPG  G  G  G                QGN GA G 
Sbjct: 672 RGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGL 731

Query: 405 PGVKGAKGGPGPRGPKGEPGRRGDPGT---KGSPGSDGPKGEK---GDPGPEGPRGLAGE 458
           PG +GA G PG +GP G+PG  G PG     G PG +GP GEK   G PGP+GP G  G 
Sbjct: 732 PGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGP 791

Query: 459 VGNKGAKGDRGL------------------------------PGPRGPQGALGEPGKQGS 488
            G KGA G RGL                              PGPRG  G  G  G+ G 
Sbjct: 792 RGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGP 851

Query: 489 RGDPGDAGPRGDSGQPGPKGDPGRPG-------FSYPGPRGAPGEK------GEPGPR-- 533
            GDPG  GP G+ G+ G  G PG PG         +PG  GA GEK      G+PGPR  
Sbjct: 852 NGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQ 911

Query: 534 ----GPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR---GVPGPEGEPGPPGD 586
               GP G RG  G+ G+PG KG  G     GPPGE GP GP+   G PGP+G PGPPG 
Sbjct: 912 RGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGK 971

Query: 587 PGL 589
            GL
Sbjct: 972 DGL 974



 Score =  290 bits (743), Expect = 3e-78
 Identities = 166/362 (45%), Positives = 194/362 (53%), Gaps = 34/362 (9%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G  G  GQ G KGN+G  GEPG  G+QG+PG +G    PGP+G  G  GEKG  G 
Sbjct: 693  PGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQG---LPGPQGAIGPPGEKGPLG- 748

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
              + G PG+ G +G  G  GK G  G  G +G PG +GP GYPG  G  G  G +G KG 
Sbjct: 749  --KPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG---------GPGPRGPKGEPGR 425
             G  G  G PG  G  G KG +G  G PG  G  G +G          PGP GP GE G+
Sbjct: 807  KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK 866

Query: 426  RGDPGTKGSPGSDGPKGE---KGDPGPEGPRGLAGEVGNKGAKGDRGLPGP---RGPQGA 479
             G PG  G PG  GPKG     G PG  G +G  G  G  G +G RG  GP   RGP+G 
Sbjct: 867  LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926

Query: 480  LGEPGKQGSRGDPGDA---------GPRGDSGQPGPKGDPGRPGF----SYPGPRGAPGE 526
             G+PG +G+ G  G A         GP+G +G PGPKG PG PG      +PG RG  G 
Sbjct: 927  TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986

Query: 527  KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
            +G+ GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP G 
Sbjct: 987  QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046

Query: 587  PG 588
            PG
Sbjct: 1047 PG 1048



 Score =  281 bits (718), Expect = 2e-75
 Identities = 157/336 (46%), Positives = 180/336 (53%), Gaps = 17/336 (5%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPG---EPGQKGRQGDPGIEGPIGFPGPK 300
            GE   V  +  PGP GP+G  G  GA G  G PG    PG  G +G+PG  G  G PG  
Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299

Query: 301  GVPGFKGEKGEFGADGRKGA---PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP---D 354
            G PG KGE+GE G  G  GA   PG  G  G DG KG  G +G PG  G PG  GP   D
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGS---KGYQGNSGAPGSPGVKGAK 411
            G PG+ G  GE G  G  G  G PG  GPPG+ G  G    +G QG  GA G  G++G  
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419

Query: 412  GGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLP 471
            G  GP GP+G PG+ G  G +G PG  G +G  G PGP+GP G  G  G  G KGD G  
Sbjct: 1420 GKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPK 1479

Query: 472  GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPG 531
            G +G  G +G  G  G +G+ GD G  G  G  GPKG+ G  G S  GP G PG  G PG
Sbjct: 1480 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPS--GPIGPPGPPGLPG 1537

Query: 532  PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPG 567
            P GP+G +G     G  G KGE G P  PGPPG PG
Sbjct: 1538 PPGPKGAKGS---SGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  280 bits (715), Expect = 5e-75
 Identities = 168/398 (42%), Positives = 198/398 (49%), Gaps = 65/398 (16%)

Query: 254 IPGPSGPKGYRGQKGAKGNM---GEPGEPGQKGRQGDPGIEGPIGFPGPKG----VPGFK 306
           I GP GP+G  G  G  G M   G+ G+PG++G  G PG+ G  G PGP G    +P   
Sbjct: 467 IEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRF 526

Query: 307 GEKGEFGADG-----------------RKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG 349
           G  G+ G+ G                 R    G AG  G  G+ G +G  G  G KG+PG
Sbjct: 527 GGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG 586

Query: 350 NRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKG 409
           + GP G  G  G PG  G  G +G  G  G RG PG+ G KG +G+ G +G PG  G +G
Sbjct: 587 DVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRG 646

Query: 410 AKGGPGPRGPKGEPGRRGD---------PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG 460
             G  GP GP G+ G RGD         PG  G  G  GPKG  G PGP G  G+ G+ G
Sbjct: 647 DPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706

Query: 461 NKGAKGDRGLPGPRGPQ---GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSY 517
            KG  G +G PGP G Q   GA G PG QG+ G PG+ GP G  G PG  G  G PG  +
Sbjct: 707 PKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPG--H 764

Query: 518 PGPRGAPGEK------------GEPGPRGPEGGRGDFGLKGEPGRKGE------------ 553
           PG  G PGEK            G PGPRG +G  G  GLKG  G KGE            
Sbjct: 765 PGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGI 824

Query: 554 ---KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
              +GE   PGP GE GP GP+G  GP G+PGP G PG
Sbjct: 825 KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPG 862



 Score =  270 bits (689), Expect = 5e-72
 Identities = 150/338 (44%), Positives = 179/338 (52%), Gaps = 8/338 (2%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G  G  G  G  G+ G+PG++G  G PG+ G  G PGP G       +   G 
Sbjct: 471 PGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGG 530

Query: 315 D-GRKGAPGLAGKNGTDG--QKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
           D G KG    A ++      Q+ +L   GP G  G  G  GP G PG  G  GE GD G 
Sbjct: 531 DAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGP 590

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
           +G  G  G  GP G+ G +G  G  G  G PG  G KG +G  G  G  GE G RGDPG 
Sbjct: 591 QGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650

Query: 432 KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGD 491
            G PG  G  GE+GD G  GPRGL GE G +G  G +G PGP GP G  G  G+ G +G+
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGN 710

Query: 492 PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRK 551
               GP+G+ G PG +G+PG  G   PGP+GA G  GE GP G  G  G  G  G PG  
Sbjct: 711 ---VGPQGEPGPPGQQGNPGAQGL--PGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHP 765

Query: 552 GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
           G++G P + G  G PGP+GP G PGP G  G  G  GL
Sbjct: 766 GKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGL 803



 Score =  256 bits (653), Expect = 8e-68
 Identities = 138/288 (47%), Positives = 156/288 (54%), Gaps = 11/288 (3%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PG  GP G +G++G KG  G  G  G  G +G PG +GP G PGP G PG  G  GE G
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G+ G PG  G +G  GQ G  G  G PG  G PG RGP   PG AG  G +G++G KG
Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP---PGPAGPEGRQGEKGAKG 1411

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            + G  G  G  G IG +G+ G  G  G  G PG  G +G PG  GP G PG  G PG  G
Sbjct: 1412 EAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG 1471

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G  GPKGEKG P   G  GL G  G +G KGDRGLPGP+G  G  GE G  G  G  G
Sbjct: 1472 LKGDSGPKGEKGHP---GLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIG 1528

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGD 541
              GP G  G PGPKG  G       GP G  GE G PGP GP G  G+
Sbjct: 1529 PPGPPGLPGPPGPKGAKGS-----SGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score =  248 bits (634), Expect = 1e-65
 Identities = 134/283 (47%), Positives = 159/283 (56%), Gaps = 11/283 (3%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG---PIGFPGPKGVPGFKGEKGEF 312
            GP GPKG RG+KG  G  G  G PG KG  GD G +G   P+GFPG  G PG  G  G+ 
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQD 1359

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372
            G  G KG  G  G+ G+ G  G+ G  GPPG +G PG  GP+G  GE G+ GE G +G  
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419

Query: 373  GDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTK 432
            G  G  G +G PG+ G  G +G  G  G  G PG  G  G PGP GP G PG +GD G K
Sbjct: 1420 GKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPK 1479

Query: 433  GS---PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSR 489
            G    PG  G  G  G+ G +G RGL G  G+ G KG++G+ GP GP   +G PG  G  
Sbjct: 1480 GEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP---IGPPGPPGLP 1536

Query: 490  GDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGP 532
            G PG  G +G SG  GPKG+ G PG   PGP G PGE  +P P
Sbjct: 1537 GPPGPKGAKGSSGPTGPKGEAGHPG--PPGPPGPPGEVIQPLP 1577



 Score =  228 bits (580), Expect = 2e-59
 Identities = 149/353 (42%), Positives = 174/353 (49%), Gaps = 56/353 (15%)

Query: 261 KGYRGQKGAKGNMGEPG--EPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRK 318
           +G  G +G KG  GEP   EPG         IEGP   PGP+G  G  G  G  G  G+ 
Sbjct: 443 EGIGGPRGEKGQKGEPAIIEPGML-------IEGP---PGPEGPAGLPGPPGTMGPTGQV 492

Query: 319 GAPGLAGKNGTDGQKGKLGRIGPP----------GCKGDPGNRGPDGYPGEAGSPGE--- 365
           G PG  G  G  G  G  G  GPP          G  GD G++GP     E+ +      
Sbjct: 493 GDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQ 552

Query: 366 -----RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
                RG  G  G  GRPG  GPPG  G KG          PG  G +G +G  GP GP 
Sbjct: 553 ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGE---------PGDVGPQGPRGVQGPPGPA 603

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           G+PGRRG        GSDG +G  G  GP+G RG  G  G  G KG RG PGP GP G  
Sbjct: 604 GKPGRRG------RAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP- 656

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
             PG  G RGD G+ GPRG  G+PGP+G  G  G   PGP G PG  G  G  GP   +G
Sbjct: 657 --PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKG--PPGPPGPPGVTGMDGQPGP---KG 709

Query: 541 DFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           + G +GEPG  G++G   +PG  G PGP+G  G PG +G  G PG PG+   D
Sbjct: 710 NVGPQGEPGPPGQQG---NPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGAD 759



 Score =  139 bits (349), Expect = 1e-32
 Identities = 82/183 (44%), Positives = 97/183 (53%), Gaps = 21/183 (11%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQ------KGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP+GP+G +G+KGAKG  G  G PG+      +G  G PG +G  G PGP G  G  G 
Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGS 1454

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGK------LGRIGPPGCKGDPGNRGPDGYPGEAGS 362
             G  G  G  G PGL G  G  G KG+      +G IGPPG +G+ G+RG  G  G +G 
Sbjct: 1455 PGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGP 1514

Query: 363  PGERGDQGGKGD---PGRPGRRGPPGEIGAKGS------KGYQGNSGAPGSPGVKGAKGG 413
             GE+G  G  G    PG PG  GPPG  GAKGS      KG  G+ G PG PG  G    
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ 1574

Query: 414  PGP 416
            P P
Sbjct: 1575 PLP 1577



 Score =  108 bits (269), Expect = 3e-23
 Identities = 61/137 (44%), Positives = 72/137 (52%), Gaps = 9/137 (6%)

Query: 254  IPGPSGPKGYRGQKGAKGN---MGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG 310
            IPGP G +G  G  G  G    MG PG PG KG  G  G +G  G  G  G PG +GEKG
Sbjct: 1442 IPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKG 1501

Query: 311  EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQG 370
            + G  G +G+ G  G+ G  G  G +G  GPPG  G PG +      G  GS G  G +G
Sbjct: 1502 DRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK------GAKGSSGPTGPKG 1555

Query: 371  GKGDPGRPGRRGPPGEI 387
              G PG PG  GPPGE+
Sbjct: 1556 EAGHPGPPGPPGPPGEV 1572


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  324 bits (831), Expect = 2e-88
 Identities = 170/350 (48%), Positives = 198/350 (56%), Gaps = 16/350 (4%)

Query: 255 PGPSGPKGYRGQKG---------AKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF 305
           PGP+GPKG  G+ G         AKG  G PG PG  G+ G PG  G  G PGP G PG 
Sbjct: 514 PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA 573

Query: 306 KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGE 365
           +G+ G  G  G KGA G  GK G  G  G  G +GP G  G+ G +GP G  G AG  GE
Sbjct: 574 RGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGE 633

Query: 366 RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
           +G  G  G  G PG  GPPGE G  G +G  G+ GAPG  G +G +G PG RG +G PG 
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693

Query: 426 RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR------GPQGA 479
            G  G  G+PG+DG KG+ G PG  G +G  G  G  G +G  GLPGP+      GP+GA
Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 480 LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGEPGPRGPEGG 538
            G PGK G RG  G  GP G +G PG KG+ G  G + P G RGAPG++GEPGP GP G 
Sbjct: 754 DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813

Query: 539 RGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G  G  G+PG KGE G+    G  G PGP GP G PGP G  G PG  G
Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKG 863



 Score =  310 bits (793), Expect = 5e-84
 Identities = 176/399 (44%), Positives = 203/399 (50%), Gaps = 68/399 (17%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GPSGP+G  G  G KGN GEPG PG KG  G  G  GP+G  GP G  G +G++G  G  
Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475

Query: 316 GRKGAPGLAGKNGTDGQKG------KLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ 369
           G  G PG  G+ G  G +G        G  GP G +G PG  GP G PGEAG PGE G  
Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP 535

Query: 370 GGKG---------------------DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVK 408
           G KG                       GRPG  GPPG  G  G  G+ G  GA G PG  
Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 409 GAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD------------PGPEGPRGLA 456
           G +G PGP G  G  G+ G+ G +G PG  GP GE+G+            PGP GP G A
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 457 GEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQP---GPKGDPGRP 513
           G+ G +G  GD G PGP G +G  G PG++G +G PG AGPRG +G P   G KGD G P
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715

Query: 514 GFSYPGPRGAPGEKGEPGPR------GPEGGRGDFGLK------------------GEPG 549
           G   PG +GAPG +G PG R      GP+G RGD G K                  G PG
Sbjct: 716 G--APGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773

Query: 550 RKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G  G+  + GP G  GP G RG PG  GEPGPPG  G
Sbjct: 774 PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812



 Score =  307 bits (786), Expect = 3e-83
 Identities = 174/384 (45%), Positives = 202/384 (52%), Gaps = 49/384 (12%)

Query: 255  PGPSGPKGYRGQKGAKGNMG------EPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP+GP G RG++G  G+ G        G PG+ G+ G+ G+ G +G PGP G  G +G 
Sbjct: 622  PGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGF 681

Query: 309  KGEFGADGRKGAPGLAGKNGT---DGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG- 364
             GE G  G  G  G  G NG    DG KG  G  G PG +G PG +G  G  G AG PG 
Sbjct: 682  PGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP 741

Query: 365  --ERGDQGGKGDPGRPGRRG---------PPGEIGAKGSKGYQGNSG------APGSPGV 407
              +RGD G KG  G PG+ G         PPG  GA G KG  G SG      A G+PG 
Sbjct: 742  KGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD 801

Query: 408  KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
            +G  G PGP G  G PG  G PG KG PG  G KG+ G PGP GP G  G +GN GA G 
Sbjct: 802  RGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA 861

Query: 468  RGLPGPRGPQGA---------LGEPGKQGSRGDPGDAGPRGDSGQPGPKGD---PGRPG- 514
            +G  G  GP GA         +G PG  G+ G PG  GP G  G  GP+G+    GRPG 
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE 921

Query: 515  FSYPGPRGAPGEKGEPGPRGPEGG---------RGDFGLKGEPGRKGEKGEPADPGPPGE 565
               PGP G  GEKG PG  GP G           G  G+ G PG++GE+G P  PGP GE
Sbjct: 922  VGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGE 981

Query: 566  PGPRGPRGVPGPEGEPGPPGDPGL 589
            PG +GP G  G  G PGP G PGL
Sbjct: 982  PGKQGPSGASGERGPPGPMGPPGL 1005



 Score =  305 bits (780), Expect = 1e-82
 Identities = 173/415 (41%), Positives = 207/415 (49%), Gaps = 82/415 (19%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G  G  G+ GE G+PG+ G +G PG +G  G PG  G+PG KG +G  G D
Sbjct: 215 GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLD 274

Query: 316 GRKG------------------APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG----- 352
           G KG                  APG  G  G  G++G+ G  GP G +G+ G  G     
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 353 -------PDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
                  P G+PG  G+ GE G QG +G  G  G RG PG  G  G+ G  GN GA G P
Sbjct: 335 GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 406 GVKGAKGGP---------------GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP- 449
           G KGA G P               GP+GP G PG +G+ G  G+PGS G  G KG+PGP 
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454

Query: 450 --EGPRGLAGEVGNKGAKGD------------------RGLP------GPRGPQGALGEP 483
             +GP G AGE G +GA+G+                  RG P      GP+GP G  G P
Sbjct: 455 GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP 514

Query: 484 GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGEPGPRGPEGGR 539
           G  G +G PG+AG  G++G PG KG  G PG   P    GP G  G+ G PGP GP G R
Sbjct: 515 GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 540 GDFGLKGEPGRKGEKGEPAD------PGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           G  G+ G PG KG  GEP        PGPPG  GP G  G  G +G PGP G  G
Sbjct: 575 GQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAG 629



 Score =  303 bits (776), Expect = 4e-82
 Identities = 181/406 (44%), Positives = 201/406 (49%), Gaps = 76/406 (18%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPG---------------EPGQKGRQGDPGIEGPIGFPGPK 300
            GPSGP G  G +GA G+ GEPG               +PG KG  GD G +G  G PGP 
Sbjct: 785  GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 301  GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
            G  G  G  G  GA G KGA G AG  G  G  G  GR+GPPG  G+ G  GP G  G+ 
Sbjct: 845  GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904

Query: 361  GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS---------------P 405
            G  G RG+ G  G PG  G  GPPG  G KGS G  G +GAPG+               P
Sbjct: 905  GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLP 964

Query: 406  GVKGAKGGPGPRGPKGEPGR---------RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLA 456
            G +G +G PG  GP GEPG+         RG PG  G PG  GP GE G  G  G  G  
Sbjct: 965  GQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSP 1024

Query: 457  GEVGNKGAKGDRGLPGPRGPQGALGEP---------GKQGSRGDPGDAGP---------R 498
            G  G+ GAKGDRG  GP GP GA G P         GK G RG+ G AGP         R
Sbjct: 1025 GRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084

Query: 499  GDSGQPGPKGDPGRP------------GFS----YPGPRGAPGEKGEPGPRGPEGGRGDF 542
            G +G  GP+GD G              GFS     PGP G+PGE+G  G  GP G RG  
Sbjct: 1085 GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPP 1144

Query: 543  GLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G  G PG+ G  G    PGP G PGPRG  G  GP G PGPPG PG
Sbjct: 1145 GSAGAPGKDGLNGL---PGPIGPPGPRGRTGDAGPVGPPGPPGPPG 1187



 Score =  301 bits (771), Expect = 2e-81
 Identities = 173/393 (44%), Positives = 198/393 (50%), Gaps = 58/393 (14%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPG---EPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG 310
           +PG  G +G+ G  GAKG+ G  G   EPG  G  G PG  GP G PG +G PG  G  G
Sbjct: 261 LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAG 320

Query: 311 EFGADGRKGA---------------PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG 355
             G DG  GA               PG  G  G  G +G  G  GP G +G+PG  GP G
Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380

Query: 356 YPGEAGSPGERGDQGGKGD---------PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG 406
             G AG+PG  G  G KG          PG PG RGP G  G  G  G +GNSG PG+PG
Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440

Query: 407 VKG---AKGGPGP------RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
            KG   AKG PGP       GP GE G+RG  G  G  G  GP GE+G PG  G  G  G
Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500

Query: 458 EVGNKGAKGDRGLPGPRGPQGALGE---------PGKQGSRGDPGDAGPRGDSGQPGPKG 508
             G KG  G+RG PGP GP+G+ GE         PG +G  G PG  GP G +G PGP G
Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG 560

Query: 509 DPGRPG-------------FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555
             GRPG               +PGP+GA GE G+ G RG  G  G  G  G+ G  G +G
Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620

Query: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            P   GP GE G +GP G PG +G PGP G PG
Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653



 Score =  301 bits (770), Expect = 2e-81
 Identities = 165/358 (46%), Positives = 189/358 (52%), Gaps = 25/358 (6%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQG---DPGIEGPIGFPGPKGVPGFKGE---K 309
           GP+GP G+ G  GAKG  G  G  G +G QG   +PG  GP G  GP G PG  G+   K
Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397

Query: 310 GEFGADGRKGAPGLAGKNGTDGQ---------KGKLGRIGPPGCKGDPGNRG---PDGYP 357
           G  GA G  GAPG  G  G  G          KG  G  G PG KGD G +G   P G  
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457

Query: 358 GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPR 417
           G  G  GE G +G +G+PG  G  GPPGE G  GS+G+ G  G  G  G  G +G PGP 
Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPA 517

Query: 418 GPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477
           GPKG PG  G PG  G PG+ G  G  G PGP+G  G  G  G  G  G  G PG RG  
Sbjct: 518 GPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA 577

Query: 478 GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS----YPGPRGAPGEKGEPGPR 533
           G +G PG +G+ G+PG AG RG  G PG  G  G+ G +     PGP G  GE+GE GP 
Sbjct: 578 GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA 637

Query: 534 GPEGGR---GDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           G  G +   G  G  GE G+ GE+G P D G PG  G RG RG PG  G  GPPG  G
Sbjct: 638 GSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAG 695



 Score =  300 bits (769), Expect = 3e-81
 Identities = 159/343 (46%), Positives = 190/343 (55%), Gaps = 14/343 (4%)

Query: 252 LEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           + +PGP GP G RG  G  G  G  G  G  G  G+PG  GP+G  GP G PG  G+ GE
Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234

Query: 312 FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            G  GR   PG  G  G  G +G  G  G PG KG  G  G DG  G+AG  G +G+ G 
Sbjct: 235 AGKPGR---PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPG------R 425
            G+ G PG+ GP G  G +G  G  G +GA G+ G  GA G PGP GP G PG       
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351

Query: 426 RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK 485
           +G+ G +G  GS+GP+G +G+PGP GP G AG  GN GA G  G  G  G  G  G PG 
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 486 QGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLK 545
            G+R   G +GP+G  G PGPKG+ G PG   PG +G  G KGEPGP G +G  G  G +
Sbjct: 412 PGAR---GPSGPQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 546 GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           G+ G +GE G    PGPPGE G  G RG PG +G  GP G  G
Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG 509



 Score =  297 bits (761), Expect = 2e-80
 Identities = 174/388 (44%), Positives = 200/388 (51%), Gaps = 56/388 (14%)

Query: 255  PGPSGPKGYRG---QKGAKGNMGEPGEPGQKGR---QGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP+GP+G  G     GAKG+ G PG PG +G    QG PG  G  G PGPKG  G  G 
Sbjct: 691  PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750

Query: 309  KGEFGADGRKGA---------PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE 359
            KG  G+ G+ G          PG AG  G  G+ G  G  GP G +G PG+RG  G PG 
Sbjct: 751  KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 360  AG------------SPGERGDQGGKGDPGRPGRRGPPG------EIGAKGSKGYQGNSGA 401
            AG            + GE GD G KGD G PG  GP G       +GA G+KG +G++G 
Sbjct: 811  AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870

Query: 402  PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKG------DPGPEGPRGL 455
            PG+ G  GA G  GP GP G  G  G PG  G  G  GP+GE G      + GP GP G 
Sbjct: 871  PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930

Query: 456  AGEVGNKGAKGDRGLPGPRGPQGALGE------PGKQGSRGDPGDAGPRGDSGQPGPKGD 509
            AGE G+ GA G  G PG  GPQG  G+      PG++G RG PG  GP G+ G+ GP G 
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 510  PGRPGFSYPGPRGAPGEKGEPGPRGPE---GGRGDFGLKGEPGRKGEKGE------PADP 560
             G  G   PGP G PG  G PG  G E   G  G  G  G PG KG++GE      P  P
Sbjct: 991  SGERG--PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAP 1048

Query: 561  GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G PG PGP GP G  G  GE GP G  G
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGETGPAGPAG 1076



 Score =  294 bits (753), Expect = 2e-79
 Identities = 174/383 (45%), Positives = 193/383 (50%), Gaps = 47/383 (12%)

Query: 253 EIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
           E  G  GPKG  G +G +G  G PG  G  G+ G PG  GP G PGP G+ G    +  +
Sbjct: 106 ETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSY 165

Query: 313 GAD----------GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS 362
           G D          G  G  G  G  G  G  G  G  GPPG  G+PG  GP G  G  G 
Sbjct: 166 GYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGP 225

Query: 363 PGERGDQGGKGDPGRPGRRGPPGEIGA------------KGSKGYQGNSGA--------- 401
           PG+ GD G  G PGRPG RGPPG  GA            KG +G+ G  GA         
Sbjct: 226 PGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGP 285

Query: 402 ---PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGE 458
              PGSPG  GA G  GPRG  GE GR G PG  G+ G+DG  G  G PGP GP G  G 
Sbjct: 286 KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGF 345

Query: 459 VGNKGAKGDRGLPGPRG---PQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF 515
            G  GAKG+ G  GPRG   PQG  GEPG  G  G  G AG  G  GQPG KG  G PG 
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 516 S-YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGP--- 571
           +  PG  GA G  G  GP GP G +G+ G  G PG KG+ G   +PGP G  GP GP   
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGE 465

Query: 572 ------RGVPGPEGEPGPPGDPG 588
                 RG PGP G PGPPG+ G
Sbjct: 466 EGKRGARGEPGPTGLPGPPGERG 488



 Score =  294 bits (753), Expect = 2e-79
 Identities = 171/373 (45%), Positives = 194/373 (52%), Gaps = 38/373 (10%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PG  G  G  G KG +G+ G  G  G  G+ G  G+ GPIG PGP G PG KGE G  G
Sbjct: 729  MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSG 788

Query: 314  A---DGRKGAPG------------LAGKNGTDGQKGKLGRIGPPGCKGD---PGNRGPDG 355
                 G +GAPG             AG  G DGQ G  G  G  G KGD   PG  GP G
Sbjct: 789  PAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAG 848

Query: 356  YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPG 415
             PG  G+ G  G +G +G  G PG  G PG  G  G  G  GN+G PG PG  G +GG G
Sbjct: 849  PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908

Query: 416  PRG---PKGEPGRRGDPGT------KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
            PRG   P G PG  G PG       KGSPG+DGP G  G PGP+G  G  G VG  G +G
Sbjct: 909  PRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRG 968

Query: 467  DRG---LPGP------RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSY 517
            +RG   LPGP      +GP GA GE G  G  G PG AGP G+SG+ G  G  G PG   
Sbjct: 969  ERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD- 1027

Query: 518  PGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGP 577
             G  GA G++GE GP GP G  G  G  G  G  G+ G+  + GP G  GP GP G  GP
Sbjct: 1028 -GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP 1086

Query: 578  EGEPGPPGDPGLT 590
             G  GP GD G T
Sbjct: 1087 AGPQGPRGDKGET 1099



 Score =  292 bits (747), Expect = 1e-78
 Identities = 159/353 (45%), Positives = 185/353 (52%), Gaps = 26/353 (7%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           + G  GP G  G  G  GN G  G+PG KG  G PGI G  GFPG +G  G +G  G  G
Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428

Query: 314 ADGRKGAPGLAGKNGTDGQKGKLGRIG---PPGCKGDPGNRGPDGYPGEAGSPGERGDQG 370
             G  G PG  G  G  G KG+ G +G   PPG  G+ G RG  G PG  G PG  G++G
Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERG 488

Query: 371 GKGDPGRPG------------RRGPPGEIGAKGSKGYQGNSGAPGSPGVKG---AKGGPG 415
           G G  G PG             RG PG  G KGS G  G  G  G PG KG   + G PG
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548

Query: 416 PRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRG 475
           P G  G PG  G  G  G PG  G +G+ G  G  GP+G AGE    G  G+RG+PGP G
Sbjct: 549 PDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE---PGKAGERGVPGPPG 605

Query: 476 PQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGP 535
             G  G+ G+ G++G PG AGP G+ G+ GP G PG  G   PGP G PGE G+PG +G 
Sbjct: 606 AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGL--PGPAGPPGEAGKPGEQGV 663

Query: 536 EGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
               GD G  G  G +GE+G P + G  G PGP GPRG  G  G  G  GD G
Sbjct: 664 P---GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713



 Score =  263 bits (673), Expect = 4e-70
 Identities = 148/329 (44%), Positives = 173/329 (52%), Gaps = 44/329 (13%)

Query: 255  PGPSGPKGYRGQKGAKGN---------MGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF 305
            PGP GP G  G KG +G          +G PG PG  G +G PG +GP G PG  G  G 
Sbjct: 895  PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 306  KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGE 365
             G++G  G  G++G  G  G  G  G+ GK G   P G  G+ G  GP G PG AG PGE
Sbjct: 955  AGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG---PSGASGERGPPGPMGPPGLAGPPGE 1011

Query: 366  RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
             G +G  G  G PGR G PG   AKG +G  G +G PG+PG  GA   PGP GP G+ G 
Sbjct: 1012 SGREGAPGAEGSPGRDGSPG---AKGDRGETGPAGPPGAPGAPGA---PGPVGPAGKSGD 1065

Query: 426  RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG---NKGAKGDRGLPGPRGPQGALGE 482
            RG+ G  G  G  GP G +G  GP+GPRG  GE G   ++G KG RG  G +GP G  G 
Sbjct: 1066 RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS 1125

Query: 483  PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDF 542
            PG+QG  G  G AGPRG    PG  G PG+ G +     G PG  G PGPR         
Sbjct: 1126 PGEQGPSGASGPAGPRGP---PGSAGAPGKDGLN-----GLPGPIGPPGPR--------- 1168

Query: 543  GLKGEPGRKGEKGEPADPGPPGEPGPRGP 571
                  GR G+ G    PGPPG PGP GP
Sbjct: 1169 ------GRTGDAGPVGPPGPPGPPGPPGP 1191



 Score =  188 bits (478), Expect = 2e-47
 Identities = 120/311 (38%), Positives = 140/311 (45%), Gaps = 76/311 (24%)

Query: 345 KGDPGNRGPDGY-----PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNS 399
           K  PG   P+G      P  + SP ++   G +G  G  G RGP      +G  G  G  
Sbjct: 79  KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGP------RGPAGPPGRD 132

Query: 400 GAPGSPGVKGAKGGPGPRGPKGEPGR---------------------------------- 425
           G PG PG+ G    PGP GP G PG                                   
Sbjct: 133 GIPGQPGLPGP---PGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL 189

Query: 426 ------------RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGP 473
                       +G PG  G PG+ GP G +G PGP G  G  GE G  G  G+RG PGP
Sbjct: 190 PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP 249

Query: 474 ---RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS----YPGPRGAPGE 526
              RG  G  G PG +G RG  G  G +GD+G  GPKG+PG PG +      GPRG PGE
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGE 309

Query: 527 KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP------GEPGPRGPRGVPGPE-- 578
           +G PG  GP G RG+ G  G  G  G  G    PG P      GE GP+GPRG  GP+  
Sbjct: 310 RGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGV 369

Query: 579 -GEPGPPGDPG 588
            GEPGPPG  G
Sbjct: 370 RGEPGPPGPAG 380



 Score =  148 bits (373), Expect = 2e-35
 Identities = 88/204 (43%), Positives = 99/204 (48%), Gaps = 29/204 (14%)

Query: 411 KGGPGPRGPKGE-----PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAK 465
           K  PG   P+GE     P     P  + + G +GPKG   D GP GPRG AG  G  G  
Sbjct: 79  KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKG---DTGPRGPRGPAGPPGRDGIP 135

Query: 466 GDRGLPGPRGPQGALGEPGKQGSRGD----------------PGDAGPRGDSGQPGPKGD 509
           G  GLPGP GP G  G PG  G+                   PG  GP G  G PGP G 
Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195

Query: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR 569
           PG  GF     +G PGE GEPG  GP G RG  G  G+ G  GE G+P  PG  G PGP+
Sbjct: 196 PGPQGF-----QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQ 250

Query: 570 GPRGVPGPEGEPGPPGDPGLTECD 593
           G RG+PG  G PG  G  G +  D
Sbjct: 251 GARGLPGTAGLPGMKGHRGFSGLD 274



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 32/75 (42%), Positives = 38/75 (50%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            + GP GP G  G++G  G  G  G  G  G  G PG +G  G PGP G PG +G  G+ G
Sbjct: 1116 LQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAG 1175

Query: 314  ADGRKGAPGLAGKNG 328
              G  G PG  G  G
Sbjct: 1176 PVGPPGPPGPPGPPG 1190



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDP 288
            +PGP GP G RG+ G  G +G PG PG  G  G P
Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  323 bits (827), Expect = 5e-88
 Identities = 183/399 (45%), Positives = 210/399 (52%), Gaps = 64/399 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP GP G+ G KG  G  G+ G PG  G++G+ G +G  G PGP GV G +G  GE G
Sbjct: 792  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 851

Query: 314  A------------DGRKGAPGLAGKNGTDGQKGKLG---RIGPPGCKGDPG--------- 349
                          G +G PG AGK GT G  G  G   + GP G +G PG         
Sbjct: 852  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911

Query: 350  ------NRGPDGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSG 400
                  N GP G PG AGSPGERG  G  G    PGRPG +GPPG  G KG  G +G  G
Sbjct: 912  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 971

Query: 401  APGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG 460
              G  GV+G  G PGP GP G  G  GD G  G PG  G KG KG+ GP GP G  G VG
Sbjct: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1031

Query: 461  NKGAKGDRGLPGPRGPQGALGEPGKQGSRGD------------PGDAGPRGDSGQPGPKG 508
              GA G  G PG RGPQG  G  G +G+RG             PG +G +G++G  GP G
Sbjct: 1032 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1091

Query: 509  DPGRPGFSYP-GPRGA---------------PGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552
             PG PG   P GP GA               PGEKGEPG  G  G +G+ G+KG  G +G
Sbjct: 1092 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1151

Query: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPGP---PGDPG 588
            EKGE   PG PG PGP+GP G  GP+G PGP   PGDPG
Sbjct: 1152 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1190



 Score =  306 bits (784), Expect = 5e-83
 Identities = 180/383 (46%), Positives = 203/383 (53%), Gaps = 50/383 (13%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGP------KGVPGFKGE 308
            PGP GP G  GQ GA G  GEPG  G +G  G  G EG  GF GP      +G+PG  GE
Sbjct: 1021 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1080

Query: 309  KGEFGADGRKGAPGL------AGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGE 359
            KGE G  G  G PG       AG NG DG +G    +G +GPPG KG+PG  G  G  GE
Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140

Query: 360  AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
             G  G RG++G KG+ G+PG  GPPG  G  G  G +GN G  G PG  G  G  GPRG 
Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200

Query: 420  KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN------KGAKGDRGL--- 470
             G  G RG+ G  G PGS GP GE G PGP G RG AG  G+      KGAKGD G    
Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1260

Query: 471  ---PGPRGPQGALGEPGKQGSRGDPGDAGPRG------DSGQPGPKGDPGRPGFSYPGPR 521
                GP GP G  G+PG  G RG PG  G +G       +G PGP G PG PG    G  
Sbjct: 1261 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR--GDA 1318

Query: 522  GAPGEKGEPG------PRGPEGGRGDFGLKGEPGRKGEKGEPADPG---------PPGEP 566
            GA GEKG PG      P G +G +GD GL G  G  G+KGE   PG         PPG P
Sbjct: 1319 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1378

Query: 567  GPRGPRGVPGPEGEPGPPGDPGL 589
            GP GP+G  G  G  GP G+ G+
Sbjct: 1379 GPAGPKGAKGATGPGGPKGEKGV 1401



 Score =  303 bits (777), Expect = 3e-82
 Identities = 164/343 (47%), Positives = 184/343 (53%), Gaps = 11/343 (3%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KGEF 312
            GP G  G +G  GA G  G PGE G  G  G  G++GP+G PGP G PG  GE   KGE 
Sbjct: 944  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1003

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG---DPGNRGPDGYPGEAGSPGERGDQ 369
            G  G+KG  G  G++G  G  G +G +G PG  G   +PG RGP G+ G  G  G RG  
Sbjct: 1004 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1063

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP 429
            G  G  G  G  GP GE G  G  G  G  G PG  G  G  G  GP+GP G  G  G P
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1123

Query: 430  GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP---QGALGEPGKQ 486
            G KG PG  G  G +G+PG +GPRG  GE G  G  G+ G PGP+GP    G  G PG  
Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1183

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKG 546
            G  GDPG  G  G  GQ G KGD G  G   PG  G+PG  GE GP GP G RG  G  G
Sbjct: 1184 GFPGDPGPPGEGGPRGQDGAKGDRGEDG--EPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1241

Query: 547  EPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
              GR+G KG   DPG  G PG  GP G  GP G+PGP G  GL
Sbjct: 1242 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1284



 Score =  301 bits (771), Expect = 2e-81
 Identities = 168/389 (43%), Positives = 199/389 (51%), Gaps = 61/389 (15%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G  G  G  G  G  G +G  GDPG++G  GF G  G+PG KG +G+ GA 
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 493

Query: 316 GRKGAPGLAGKNGTDGQ------------KGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
           G  G PG  G+ G DG+            +G LG  GPPG  G PG RG DG  G  GS 
Sbjct: 494 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 553

Query: 364 GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
           G +G+ G  G  G PG +G PG  GA G  G +G  G PG PG+      PG  GP G P
Sbjct: 554 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM------PGSDGPPGHP 607

Query: 424 GRRGDPGTKGSPGSDGPKGEKGDPGPEGPR---GLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           G+ G PGTKG+ G  GP+G  G PGP G +   G+ G  G+KG KG+ G PG +G  G  
Sbjct: 608 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 667

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-------------------------F 515
           G+ G+ G  G  G+ GP G  G+ GP GDPG PG                          
Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 727

Query: 516 SYPGPRGAPGEK------------GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            +PG  GA GEK            GE GP GP G RG  G  G+ G KG  G     GPP
Sbjct: 728 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 787

Query: 564 GE---PGPRGPRGVPGPEGEPGPPGDPGL 589
           GE   PGP+GP G PGP+G PGPPG  GL
Sbjct: 788 GERGLPGPQGPNGFPGPKGPPGPPGKDGL 816



 Score =  301 bits (771), Expect = 2e-81
 Identities = 165/381 (43%), Positives = 208/381 (54%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGFPGPKGV---PG 304
            +PGP+GP G  G+ G KG +G+PG+ G KG +G+      PG  GP+G PG  G    PG
Sbjct: 984  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1043

Query: 305  FKGEKGEFGADGRKGAP---------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNR---- 351
             +G +G FGA G +G           GL G  G  G+KG+ G +GP G  G PG R    
Sbjct: 1044 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1103

Query: 352  -----GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG 406
                 GP G PG  G+ G  G++G  G+ G PG +G PG  G +G +G +G SG PG PG
Sbjct: 1104 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1163

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G KG  G  GPKG PG  G PG  G PG  GP+G+ G  G  G  G  G+ G+ G  G
Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1223

Query: 467  DRGLPGPRGPQGALGEPGKQ------GSRGDP---------GDAGPRGDSGQPGPKGDPG 511
            + G PGP G +G  G PG +      G++GDP         G  GP G +G+PGP G  G
Sbjct: 1224 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1283

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GL+G+ G KGEKG P      GPPGE G 
Sbjct: 1284 LPG--SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1341

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PGP+G PG  G+ G+
Sbjct: 1342 KGDRGLPGPQGSPGQKGEMGI 1362



 Score =  298 bits (764), Expect = 1e-80
 Identities = 168/365 (46%), Positives = 195/365 (53%), Gaps = 38/365 (10%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG---------PIGFPGPKG--- 301
           IPGP G +G  G +G KG++G  GEPG  G+QG PG +G         P G  GP+G   
Sbjct: 534 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 593

Query: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
           +PG  G  G  G  G++G PG  G  G  G +G LG  GP G KG  G RG  G+ GE G
Sbjct: 594 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 653

Query: 362 S---PGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG----- 413
               PG +GD G KGD G  G  G  GE G +G KG  G +G PG PG+ G KG      
Sbjct: 654 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713

Query: 414 ----PGPRGPKGE------PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463
               PG +GPKG       PG  G+ G +G  G  GP+GE+G  GP G RG  G  G  G
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 773

Query: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523
           AKG  G  GP GP G  G PG QG  G PG  GP      PGP G  G PG  +PG RG 
Sbjct: 774 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP------PGPPGKDGLPG--HPGQRGE 825

Query: 524 PGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            G +G+ GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP
Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 885

Query: 584 PGDPG 588
           PG PG
Sbjct: 886 PGAPG 890



 Score =  298 bits (762), Expect = 2e-80
 Identities = 170/390 (43%), Positives = 195/390 (50%), Gaps = 52/390 (13%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
           GP G  G  G  G+ G  G PG+   PG KG QG  G +GP+G+PGP+GV G  G +G  
Sbjct: 587 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 646

Query: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP------GER 366
           G  G KG  G  G  G  G KG  G +G PG +G+ G  GP G  G  G P      GE+
Sbjct: 647 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 706

Query: 367 GDQGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
           G  G  G PG PGR+GP      PG  GA G KG +G SG  G  G +G  G  G RGP+
Sbjct: 707 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 766

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGL---------------------AGEV 459
           G  G+ G  GT G  G  GP GE+G PGP+GP G                       GEV
Sbjct: 767 GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 826

Query: 460 GNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQP------GPKGDPGRP 513
           G +G  G  G PG  GPQGA GE G  G RG PG  GP G+ G P      G KGDPG P
Sbjct: 827 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886

Query: 514 GF----------SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
           G            +PG RG PG  G PG +G EG  G  G  G PG +G  G     GPP
Sbjct: 887 GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 946

Query: 564 GEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           G PGP+GP G  G +G PG  G  G T  D
Sbjct: 947 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 976



 Score =  295 bits (754), Expect = 2e-79
 Identities = 161/359 (44%), Positives = 189/359 (52%), Gaps = 32/359 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG--- 310
            +PG +G  G +G +G  G  G  G PG++G  G  G  GP G PGP+G PG  GEKG   
Sbjct: 906  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965

Query: 311  ---------EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
                       G  G  G PG AG  G  G+ G  G +G PG KG  GN+G  G PG  G
Sbjct: 966  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1025

Query: 362  SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---------KGAKG 412
              G  G  G  G  G PG RGP G  GAKG +G +G +G PG  G+         KG  G
Sbjct: 1026 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085

Query: 413  GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPG 472
              GP GP G PG RG  G  G+ G  GP G  G+ GP G +G  GE G+ G +G+ G+ G
Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1145

Query: 473  PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGP 532
            PRG +G  GE G+ G  G PG  GP GD    GPKG+PG  GF      G PG  GE GP
Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFP-----GDPGPPGEGGP 1197

Query: 533  RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE---PGPPGDPG 588
            RG +G +GD G  GEPG+ G  G   + GPPG  G RGP G PG EG     G  GDPG
Sbjct: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1256



 Score =  293 bits (749), Expect = 6e-79
 Identities = 164/372 (44%), Positives = 193/372 (51%), Gaps = 41/372 (11%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG------VPGFKGEK 309
            G  GP+G +G+ G  G+ G PG  G+KG+ G PG+ G  G  GPKG       PG  GEK
Sbjct: 680  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 739

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ 369
            G  G  G+ G  G  G  G  GQ+G  G  G  G KG  G  GP G PGE G PG +G  
Sbjct: 740  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 799

Query: 370  G---GKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG------------P 414
            G    KG PG PG+ G PG  G +G  G+QG +G PG PGV G +G             P
Sbjct: 800  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 859

Query: 415  GPRGPKGEPG---------RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAK 465
            GP GP GE G          +GDPG  G+PG DGP G +G PG  G  G AG  G KG +
Sbjct: 860  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919

Query: 466  GDRGLPGPRGPQ---------GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
            G  G PGP G           G +G PG+ G +G PG AG +G  G+ GP G  GR G  
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 517  YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576
              GP G PG  G PG  G +G +G+ G  G+ G KG KGE   PGPPG  GP G  G  G
Sbjct: 980  --GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1037

Query: 577  PEGEPGPPGDPG 588
             +GEPG  G  G
Sbjct: 1038 ADGEPGARGPQG 1049



 Score =  290 bits (741), Expect = 5e-78
 Identities = 159/358 (44%), Positives = 190/358 (53%), Gaps = 26/358 (7%)

Query: 256 GPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
           GP GP GY   RG KG  G  G  G  G+KG  G PG +G IG  G +G  G  G +GE 
Sbjct: 623 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 682

Query: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG---YPGEAGSPGERGDQ 369
           G +G KG  G  G  G  G  G+ G++G PG  G PG +GP G   +PG  G+ GE+G +
Sbjct: 683 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742

Query: 370 GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS---------------PGVKGAKGGP 414
           G  G  G  G RGP G  G +G +G  G SGA G+               PG +G  G P
Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 415 GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGLP 471
           GP+GP G PG+ G PG  G  G  G +G+ G PGP    GP+G AGE G  G +G  G P
Sbjct: 803 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 472 GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPG 531
           GP G QG  G  GK+G++GDPG  G  G  G  G +G PG  G   PG  G PG KG  G
Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--PGTAGGPGLKGNEG 920

Query: 532 PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
           P GP G  G  G +G  G  G  G P  PGP G PG  G +GVPG +G  GP G  G+
Sbjct: 921 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978



 Score =  288 bits (738), Expect = 1e-77
 Identities = 179/419 (42%), Positives = 203/419 (48%), Gaps = 82/419 (19%)

Query: 252  LEIPGPSGPKGY------RGQKGAKGNMGEP------------GEPGQKGRQGDPGIEGP 293
            L  PGP G KG       +G KG KG  G P            GE G  G +G+ G EGP
Sbjct: 628  LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 687

Query: 294  IGFPGP---KGVPGFKGEKGEF------------------------GADGRKGAPGLAGK 326
             G  GP    G PG  GEKG+                         GA G KGA GL+GK
Sbjct: 688  KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 747

Query: 327  N---------GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ---GGKGD 374
            +         G  GQ+G  G  G  G KG  G  GP G PGE G PG +G     G KG 
Sbjct: 748  SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 807

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---KGAKGGPGPRGPKGEPGRRGDPGT 431
            PG PG+ G PG  G +G  G+QG +G PG PGV   +GA G  GP G +G PG  G PG 
Sbjct: 808  PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE 867

Query: 432  KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGD 491
            +G PG+ G +G KGDPGP G  G  G  G +G  G+RGLPG  G  G  G  G  G  G 
Sbjct: 868  QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP 927

Query: 492  PGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------------PGP 532
             G  G RG +G  GP G PGRPG   P    G +G PGEKG                PGP
Sbjct: 928  AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 987

Query: 533  RGPEGGRGDFGLKGE---PGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             GP G  G+ G KGE   PG+KG KG   + GPPG PGP GP G PG  G  G PG  G
Sbjct: 988  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1046



 Score =  278 bits (710), Expect = 2e-74
 Identities = 161/350 (46%), Positives = 187/350 (53%), Gaps = 31/350 (8%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKG---------NMGEPGEPGQKGRQGDPGIEGPI 294
            GE   V  +  PGP GP+G  G  GA G         N+G PGE G+ G  G PGI+G  
Sbjct: 1082 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE- 1140

Query: 295  GFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPD 354
              PG KG  G +GEKGE G  G  G PG  G  G DG KG  G +G PG  G PG  GP 
Sbjct: 1141 --PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP- 1197

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
                  G  G +GD+G  G+PG+PG  GP GE G  G  G +G +G+PGS G +G KG  
Sbjct: 1198 -----RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA- 1251

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
                 KG+PG  G PG  G  G  GP G+   PGP+G RGL G VG +G  G  G  GP 
Sbjct: 1252 -----KGDPGAIGAPGKTGPVGPAGPAGK---PGPDGLRGLPGSVGQQGRPGATGQAGPP 1303

Query: 475  GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGE---P 530
            GP G  G PG +G  G  G+ G  G  G  GP G+ G  G    PGP+G+PG+KGE   P
Sbjct: 1304 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1363

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
            G  GP G  G  GL G  G KG KG     GP GE G +GP G PGP GE
Sbjct: 1364 GASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1413



 Score =  271 bits (693), Expect = 2e-72
 Identities = 161/389 (41%), Positives = 192/389 (49%), Gaps = 60/389 (15%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G  G  G +GN G  G+PG++G  G  G+ G  G PGP G       +  FG+
Sbjct: 315 PGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGS 372

Query: 315 DGRKGAPGLAGKNGTDG---QKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            G    P +A +        Q+ +L   GPPG  G  G  GP G PG  G  GE GD G 
Sbjct: 373 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 432

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
           +G  G  G  GPPG+ G +G  G  G  G PG PGVKG +G  G  G  GE G RGD G 
Sbjct: 433 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492

Query: 432 KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK---GAKGDRGLPGP--------------- 473
           +G PG  G  GE+GD G  GPRGL GE G +   G KG  G+PGP               
Sbjct: 493 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 552

Query: 474 RGPQGALGEPGKQGSRGDPGDAGPR---GDSGQPGPKGDPGRPGF-------SYPGPRGA 523
            GPQG  G PG+QG+ G  G  GP+   G  G+ GP+G PG PG         +PG  G 
Sbjct: 553 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 612

Query: 524 PGEKGEPGPRGPEG--------------------------GRGDF-GLKGEPGRKGEKGE 556
           PG KG  GP GP+G                          G   F G KG+ G KG++GE
Sbjct: 613 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 672

Query: 557 PADPGPPGEPGPRGPRGVPGPEGEPGPPG 585
              PG  GE GP GP+G  GP G+PGPPG
Sbjct: 673 VGVPGSRGEDGPEGPKGRTGPTGDPGPPG 701



 Score =  219 bits (557), Expect = 1e-56
 Identities = 136/334 (40%), Positives = 163/334 (48%), Gaps = 68/334 (20%)

Query: 298 GPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYP 357
           GP+G+ G KGE            PG+  + G  G +G  G IGPPG +G+PG   P G P
Sbjct: 291 GPRGLKGEKGEPAVL-------EPGMLVE-GPPGPEGPAGLIGPPGIQGNPG---PVGDP 339

Query: 358 GEAGSPGERGDQGGKGDPGRPGR------------------------------------- 380
           GE G PG  G  G  G PG PG                                      
Sbjct: 340 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 399

Query: 381 RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP 440
           RGPPG +G  G  G  G  G+PG  G  G  G  GPRGP+G  G  G  G +G  G+DG 
Sbjct: 400 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 459

Query: 441 KGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGD 500
           +G  GDPG +G RG  G  G  G KG RG     G QG  G PG+ G RGD G+ GPRG 
Sbjct: 460 RGMPGDPGVKGDRGFDGLPGLPGEKGHRG---DTGAQGLPGPPGEDGERGDDGEIGPRGL 516

Query: 501 SGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEP 557
            G+ GP+G          GP+G PG  G PG RG   P+G +G  G +GEPG  G++G P
Sbjct: 517 PGESGPRG--------LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 568

Query: 558 ADPGPPGEPGPR---GPRGVPGPEGEPGPPGDPG 588
              G  G PGP+   GP G  GP+G+PG PG PG
Sbjct: 569 ---GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599



 Score =  179 bits (455), Expect = 7e-45
 Identities = 115/283 (40%), Positives = 128/283 (45%), Gaps = 58/283 (20%)

Query: 340 GPPGCKGDPGN----------RGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389
           GP G KG+ G            GP G  G AG  G  G QG  G  G PG RGPPG    
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 348

Query: 390 KGSKGYQGNSGAPGSPGVK-----GAKGGPGPRGP--------------KGEPGRRGDPG 430
               G  G+ GAPG PG           G G +GP              +     RG PG
Sbjct: 349 ----GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 404

Query: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRG 490
             G  G  GP G+ G PG             KG  GD G  GPRGPQG  G PGK G RG
Sbjct: 405 PMGYTGRPGPLGQPGSPGL------------KGESGDLGPQGPRGPQGLTGPPGKAGRRG 452

Query: 491 DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550
             G  G RG  G PG KGD G     + G  G PGEKG  G  G +G      L G PG 
Sbjct: 453 RAGADGARGMPGDPGVKGDRG-----FDGLPGLPGEKGHRGDTGAQG------LPGPPGE 501

Query: 551 KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            GE+G+  + GP G PG  GPRG+ GP+G PG PG PG+   D
Sbjct: 502 DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 544



 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 46/108 (42%), Positives = 54/108 (50%), Gaps = 15/108 (13%)

Query: 242  AYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG 301
            A GE      + + GP G +G +G +G  G  G PG+   KG  G PG  GPIG  GP G
Sbjct: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ---KGEMGIPGASGPIGPGGPPG 1376

Query: 302  VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG 349
            +PG  G KG  GA G    PG        G KG+ G  GPPG  G PG
Sbjct: 1377 LPGPAGPKGAKGATG----PG--------GPKGEKGVQGPPGHPGPPG 1412



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 16/37 (43%), Positives = 18/37 (48%), Gaps = 10/37 (27%)

Query: 562 PPGEPGPRGPRGVPGPEGEP----------GPPGDPG 588
           PP E    GPRG+ G +GEP          GPPG  G
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEG 319


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  323 bits (827), Expect = 5e-88
 Identities = 183/399 (45%), Positives = 210/399 (52%), Gaps = 64/399 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP GP G+ G KG  G  G+ G PG  G++G+ G +G  G PGP GV G +G  GE G
Sbjct: 771  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 830

Query: 314  A------------DGRKGAPGLAGKNGTDGQKGKLG---RIGPPGCKGDPG--------- 349
                          G +G PG AGK GT G  G  G   + GP G +G PG         
Sbjct: 831  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890

Query: 350  ------NRGPDGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSG 400
                  N GP G PG AGSPGERG  G  G    PGRPG +GPPG  G KG  G +G  G
Sbjct: 891  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 950

Query: 401  APGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG 460
              G  GV+G  G PGP GP G  G  GD G  G PG  G KG KG+ GP GP G  G VG
Sbjct: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1010

Query: 461  NKGAKGDRGLPGPRGPQGALGEPGKQGSRGD------------PGDAGPRGDSGQPGPKG 508
              GA G  G PG RGPQG  G  G +G+RG             PG +G +G++G  GP G
Sbjct: 1011 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1070

Query: 509  DPGRPGFSYP-GPRGA---------------PGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552
             PG PG   P GP GA               PGEKGEPG  G  G +G+ G+KG  G +G
Sbjct: 1071 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1130

Query: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPGP---PGDPG 588
            EKGE   PG PG PGP+GP G  GP+G PGP   PGDPG
Sbjct: 1131 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169



 Score =  306 bits (784), Expect = 5e-83
 Identities = 180/383 (46%), Positives = 203/383 (53%), Gaps = 50/383 (13%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGP------KGVPGFKGE 308
            PGP GP G  GQ GA G  GEPG  G +G  G  G EG  GF GP      +G+PG  GE
Sbjct: 1000 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1059

Query: 309  KGEFGADGRKGAPGL------AGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGE 359
            KGE G  G  G PG       AG NG DG +G    +G +GPPG KG+PG  G  G  GE
Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119

Query: 360  AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
             G  G RG++G KG+ G+PG  GPPG  G  G  G +GN G  G PG  G  G  GPRG 
Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179

Query: 420  KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN------KGAKGDRGL--- 470
             G  G RG+ G  G PGS GP GE G PGP G RG AG  G+      KGAKGD G    
Sbjct: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1239

Query: 471  ---PGPRGPQGALGEPGKQGSRGDPGDAGPRG------DSGQPGPKGDPGRPGFSYPGPR 521
                GP GP G  G+PG  G RG PG  G +G       +G PGP G PG PG    G  
Sbjct: 1240 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR--GDA 1297

Query: 522  GAPGEKGEPG------PRGPEGGRGDFGLKGEPGRKGEKGEPADPG---------PPGEP 566
            GA GEKG PG      P G +G +GD GL G  G  G+KGE   PG         PPG P
Sbjct: 1298 GAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLP 1357

Query: 567  GPRGPRGVPGPEGEPGPPGDPGL 589
            GP GP+G  G  G  GP G+ G+
Sbjct: 1358 GPAGPKGAKGATGPGGPKGEKGV 1380



 Score =  303 bits (777), Expect = 3e-82
 Identities = 164/343 (47%), Positives = 184/343 (53%), Gaps = 11/343 (3%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KGEF 312
            GP G  G +G  GA G  G PGE G  G  G  G++GP+G PGP G PG  GE   KGE 
Sbjct: 923  GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 982

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG---DPGNRGPDGYPGEAGSPGERGDQ 369
            G  G+KG  G  G++G  G  G +G +G PG  G   +PG RGP G+ G  G  G RG  
Sbjct: 983  GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1042

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP 429
            G  G  G  G  GP GE G  G  G  G  G PG  G  G  G  GP+GP G  G  G P
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1102

Query: 430  GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP---QGALGEPGKQ 486
            G KG PG  G  G +G+PG +GPRG  GE G  G  G+ G PGP+GP    G  G PG  
Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1162

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKG 546
            G  GDPG  G  G  GQ G KGD G  G   PG  G+PG  GE GP GP G RG  G  G
Sbjct: 1163 GFPGDPGPPGEGGPRGQDGAKGDRGEDG--EPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1220

Query: 547  EPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
              GR+G KG   DPG  G PG  GP G  GP G+PGP G  GL
Sbjct: 1221 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1263



 Score =  301 bits (771), Expect = 2e-81
 Identities = 168/389 (43%), Positives = 199/389 (51%), Gaps = 61/389 (15%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G  G  G  G  G  G +G  GDPG++G  GF G  G+PG KG +G+ GA 
Sbjct: 413 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 472

Query: 316 GRKGAPGLAGKNGTDGQ------------KGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
           G  G PG  G+ G DG+            +G LG  GPPG  G PG RG DG  G  GS 
Sbjct: 473 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532

Query: 364 GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
           G +G+ G  G  G PG +G PG  GA G  G +G  G PG PG+      PG  GP G P
Sbjct: 533 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM------PGSDGPPGHP 586

Query: 424 GRRGDPGTKGSPGSDGPKGEKGDPGPEGPR---GLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           G+ G PGTKG+ G  GP+G  G PGP G +   G+ G  G+KG KG+ G PG +G  G  
Sbjct: 587 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 646

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-------------------------F 515
           G+ G+ G  G  G+ GP G  G+ GP GDPG PG                          
Sbjct: 647 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 706

Query: 516 SYPGPRGAPGEK------------GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            +PG  GA GEK            GE GP GP G RG  G  G+ G KG  G     GPP
Sbjct: 707 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 766

Query: 564 GE---PGPRGPRGVPGPEGEPGPPGDPGL 589
           GE   PGP+GP G PGP+G PGPPG  GL
Sbjct: 767 GERGLPGPQGPNGFPGPKGPPGPPGKDGL 795



 Score =  301 bits (771), Expect = 2e-81
 Identities = 165/381 (43%), Positives = 208/381 (54%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGFPGPKGV---PG 304
            +PGP+GP G  G+ G KG +G+PG+ G KG +G+      PG  GP+G PG  G    PG
Sbjct: 963  LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1022

Query: 305  FKGEKGEFGADGRKGAP---------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNR---- 351
             +G +G FGA G +G           GL G  G  G+KG+ G +GP G  G PG R    
Sbjct: 1023 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1082

Query: 352  -----GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG 406
                 GP G PG  G+ G  G++G  G+ G PG +G PG  G +G +G +G SG PG PG
Sbjct: 1083 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G KG  G  GPKG PG  G PG  G PG  GP+G+ G  G  G  G  G+ G+ G  G
Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1202

Query: 467  DRGLPGPRGPQGALGEPGKQ------GSRGDP---------GDAGPRGDSGQPGPKGDPG 511
            + G PGP G +G  G PG +      G++GDP         G  GP G +G+PGP G  G
Sbjct: 1203 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1262

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GL+G+ G KGEKG P      GPPGE G 
Sbjct: 1263 LPG--SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PGP+G PG  G+ G+
Sbjct: 1321 KGDRGLPGPQGSPGQKGEMGI 1341



 Score =  298 bits (764), Expect = 1e-80
 Identities = 168/365 (46%), Positives = 195/365 (53%), Gaps = 38/365 (10%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG---------PIGFPGPKG--- 301
           IPGP G +G  G +G KG++G  GEPG  G+QG PG +G         P G  GP+G   
Sbjct: 513 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 572

Query: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
           +PG  G  G  G  G++G PG  G  G  G +G LG  GP G KG  G RG  G+ GE G
Sbjct: 573 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632

Query: 362 S---PGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG----- 413
               PG +GD G KGD G  G  G  GE G +G KG  G +G PG PG+ G KG      
Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692

Query: 414 ----PGPRGPKGE------PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463
               PG +GPKG       PG  G+ G +G  G  GP+GE+G  GP G RG  G  G  G
Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 752

Query: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523
           AKG  G  GP GP G  G PG QG  G PG  GP      PGP G  G PG  +PG RG 
Sbjct: 753 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP------PGPPGKDGLPG--HPGQRGE 804

Query: 524 PGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            G +G+ GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 864

Query: 584 PGDPG 588
           PG PG
Sbjct: 865 PGAPG 869



 Score =  298 bits (762), Expect = 2e-80
 Identities = 170/390 (43%), Positives = 195/390 (50%), Gaps = 52/390 (13%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
           GP G  G  G  G+ G  G PG+   PG KG QG  G +GP+G+PGP+GV G  G +G  
Sbjct: 566 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 625

Query: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP------GER 366
           G  G KG  G  G  G  G KG  G +G PG +G+ G  GP G  G  G P      GE+
Sbjct: 626 GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 685

Query: 367 GDQGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
           G  G  G PG PGR+GP      PG  GA G KG +G SG  G  G +G  G  G RGP+
Sbjct: 686 GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 745

Query: 421 GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGL---------------------AGEV 459
           G  G+ G  GT G  G  GP GE+G PGP+GP G                       GEV
Sbjct: 746 GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 805

Query: 460 GNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQP------GPKGDPGRP 513
           G +G  G  G PG  GPQGA GE G  G RG PG  GP G+ G P      G KGDPG P
Sbjct: 806 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865

Query: 514 GF----------SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
           G            +PG RG PG  G PG +G EG  G  G  G PG +G  G     GPP
Sbjct: 866 GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 925

Query: 564 GEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           G PGP+GP G  G +G PG  G  G T  D
Sbjct: 926 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955



 Score =  295 bits (754), Expect = 2e-79
 Identities = 161/359 (44%), Positives = 189/359 (52%), Gaps = 32/359 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG--- 310
            +PG +G  G +G +G  G  G  G PG++G  G  G  GP G PGP+G PG  GEKG   
Sbjct: 885  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944

Query: 311  ---------EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
                       G  G  G PG AG  G  G+ G  G +G PG KG  GN+G  G PG  G
Sbjct: 945  EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004

Query: 362  SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---------KGAKG 412
              G  G  G  G  G PG RGP G  GAKG +G +G +G PG  G+         KG  G
Sbjct: 1005 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064

Query: 413  GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPG 472
              GP GP G PG RG  G  G+ G  GP G  G+ GP G +G  GE G+ G +G+ G+ G
Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124

Query: 473  PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGP 532
            PRG +G  GE G+ G  G PG  GP GD    GPKG+PG  GF      G PG  GE GP
Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFP-----GDPGPPGEGGP 1176

Query: 533  RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE---PGPPGDPG 588
            RG +G +GD G  GEPG+ G  G   + GPPG  G RGP G PG EG     G  GDPG
Sbjct: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1235



 Score =  293 bits (749), Expect = 6e-79
 Identities = 164/372 (44%), Positives = 193/372 (51%), Gaps = 41/372 (11%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG------VPGFKGEK 309
            G  GP+G +G+ G  G+ G PG  G+KG+ G PG+ G  G  GPKG       PG  GEK
Sbjct: 659  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 718

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ 369
            G  G  G+ G  G  G  G  GQ+G  G  G  G KG  G  GP G PGE G PG +G  
Sbjct: 719  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 778

Query: 370  G---GKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG------------P 414
            G    KG PG PG+ G PG  G +G  G+QG +G PG PGV G +G             P
Sbjct: 779  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 838

Query: 415  GPRGPKGEPG---------RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAK 465
            GP GP GE G          +GDPG  G+PG DGP G +G PG  G  G AG  G KG +
Sbjct: 839  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898

Query: 466  GDRGLPGPRGPQ---------GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
            G  G PGP G           G +G PG+ G +G PG AG +G  G+ GP G  GR G  
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 517  YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576
              GP G PG  G PG  G +G +G+ G  G+ G KG KGE   PGPPG  GP G  G  G
Sbjct: 959  --GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016

Query: 577  PEGEPGPPGDPG 588
             +GEPG  G  G
Sbjct: 1017 ADGEPGARGPQG 1028



 Score =  290 bits (741), Expect = 5e-78
 Identities = 159/358 (44%), Positives = 190/358 (53%), Gaps = 26/358 (7%)

Query: 256 GPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
           GP GP GY   RG KG  G  G  G  G+KG  G PG +G IG  G +G  G  G +GE 
Sbjct: 602 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661

Query: 313 GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG---YPGEAGSPGERGDQ 369
           G +G KG  G  G  G  G  G+ G++G PG  G PG +GP G   +PG  G+ GE+G +
Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 721

Query: 370 GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS---------------PGVKGAKGGP 414
           G  G  G  G RGP G  G +G +G  G SGA G+               PG +G  G P
Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 415 GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE---GPRGLAGEVGNKGAKGDRGLP 471
           GP+GP G PG+ G PG  G  G  G +G+ G PGP    GP+G AGE G  G +G  G P
Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841

Query: 472 GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPG 531
           GP G QG  G  GK+G++GDPG  G  G  G  G +G PG  G   PG  G PG KG  G
Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--PGTAGGPGLKGNEG 899

Query: 532 PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
           P GP G  G  G +G  G  G  G P  PGP G PG  G +GVPG +G  GP G  G+
Sbjct: 900 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957



 Score =  288 bits (738), Expect = 1e-77
 Identities = 179/419 (42%), Positives = 203/419 (48%), Gaps = 82/419 (19%)

Query: 252  LEIPGPSGPKGY------RGQKGAKGNMGEP------------GEPGQKGRQGDPGIEGP 293
            L  PGP G KG       +G KG KG  G P            GE G  G +G+ G EGP
Sbjct: 607  LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 666

Query: 294  IGFPGP---KGVPGFKGEKGEF------------------------GADGRKGAPGLAGK 326
             G  GP    G PG  GEKG+                         GA G KGA GL+GK
Sbjct: 667  KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726

Query: 327  N---------GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ---GGKGD 374
            +         G  GQ+G  G  G  G KG  G  GP G PGE G PG +G     G KG 
Sbjct: 727  SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 786

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---KGAKGGPGPRGPKGEPGRRGDPGT 431
            PG PG+ G PG  G +G  G+QG +G PG PGV   +GA G  GP G +G PG  G PG 
Sbjct: 787  PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE 846

Query: 432  KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGD 491
            +G PG+ G +G KGDPGP G  G  G  G +G  G+RGLPG  G  G  G  G  G  G 
Sbjct: 847  QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP 906

Query: 492  PGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------------PGP 532
             G  G RG +G  GP G PGRPG   P    G +G PGEKG                PGP
Sbjct: 907  AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 966

Query: 533  RGPEGGRGDFGLKGE---PGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             GP G  G+ G KGE   PG+KG KG   + GPPG PGP GP G PG  G  G PG  G
Sbjct: 967  AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1025



 Score =  278 bits (710), Expect = 2e-74
 Identities = 161/350 (46%), Positives = 187/350 (53%), Gaps = 31/350 (8%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKG---------NMGEPGEPGQKGRQGDPGIEGPI 294
            GE   V  +  PGP GP+G  G  GA G         N+G PGE G+ G  G PGI+G  
Sbjct: 1061 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE- 1119

Query: 295  GFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPD 354
              PG KG  G +GEKGE G  G  G PG  G  G DG KG  G +G PG  G PG  GP 
Sbjct: 1120 --PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP- 1176

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
                  G  G +GD+G  G+PG+PG  GP GE G  G  G +G +G+PGS G +G KG  
Sbjct: 1177 -----RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA- 1230

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
                 KG+PG  G PG  G  G  GP G+   PGP+G RGL G VG +G  G  G  GP 
Sbjct: 1231 -----KGDPGAIGAPGKTGPVGPAGPAGK---PGPDGLRGLPGSVGQQGRPGATGQAGPP 1282

Query: 475  GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGE---P 530
            GP G  G PG +G  G  G+ G  G  G  GP G+ G  G    PGP+G+PG+KGE   P
Sbjct: 1283 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1342

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
            G  GP G  G  GL G  G KG KG     GP GE G +GP G PGP GE
Sbjct: 1343 GASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1392



 Score =  271 bits (693), Expect = 2e-72
 Identities = 161/389 (41%), Positives = 192/389 (49%), Gaps = 60/389 (15%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G  G  G +GN G  G+PG++G  G  G+ G  G PGP G       +  FG+
Sbjct: 294 PGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGS 351

Query: 315 DGRKGAPGLAGKNGTDG---QKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            G    P +A +        Q+ +L   GPPG  G  G  GP G PG  G  GE GD G 
Sbjct: 352 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 411

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
           +G  G  G  GPPG+ G +G  G  G  G PG PGVKG +G  G  G  GE G RGD G 
Sbjct: 412 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471

Query: 432 KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK---GAKGDRGLPGP--------------- 473
           +G PG  G  GE+GD G  GPRGL GE G +   G KG  G+PGP               
Sbjct: 472 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 531

Query: 474 RGPQGALGEPGKQGSRGDPGDAGPR---GDSGQPGPKGDPGRPGF-------SYPGPRGA 523
            GPQG  G PG+QG+ G  G  GP+   G  G+ GP+G PG PG         +PG  G 
Sbjct: 532 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 591

Query: 524 PGEKGEPGPRGPEG--------------------------GRGDF-GLKGEPGRKGEKGE 556
           PG KG  GP GP+G                          G   F G KG+ G KG++GE
Sbjct: 592 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 651

Query: 557 PADPGPPGEPGPRGPRGVPGPEGEPGPPG 585
              PG  GE GP GP+G  GP G+PGPPG
Sbjct: 652 VGVPGSRGEDGPEGPKGRTGPTGDPGPPG 680



 Score =  219 bits (557), Expect = 1e-56
 Identities = 136/334 (40%), Positives = 163/334 (48%), Gaps = 68/334 (20%)

Query: 298 GPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYP 357
           GP+G+ G KGE            PG+  + G  G +G  G IGPPG +G+PG   P G P
Sbjct: 270 GPRGLKGEKGEPAVL-------EPGMLVE-GPPGPEGPAGLIGPPGIQGNPG---PVGDP 318

Query: 358 GEAGSPGERGDQGGKGDPGRPGR------------------------------------- 380
           GE G PG  G  G  G PG PG                                      
Sbjct: 319 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 378

Query: 381 RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP 440
           RGPPG +G  G  G  G  G+PG  G  G  G  GPRGP+G  G  G  G +G  G+DG 
Sbjct: 379 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 438

Query: 441 KGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGD 500
           +G  GDPG +G RG  G  G  G KG RG     G QG  G PG+ G RGD G+ GPRG 
Sbjct: 439 RGMPGDPGVKGDRGFDGLPGLPGEKGHRG---DTGAQGLPGPPGEDGERGDDGEIGPRGL 495

Query: 501 SGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEP 557
            G+ GP+G          GP+G PG  G PG RG   P+G +G  G +GEPG  G++G P
Sbjct: 496 PGESGPRG--------LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 547

Query: 558 ADPGPPGEPGPR---GPRGVPGPEGEPGPPGDPG 588
              G  G PGP+   GP G  GP+G+PG PG PG
Sbjct: 548 ---GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578



 Score =  179 bits (455), Expect = 7e-45
 Identities = 115/283 (40%), Positives = 128/283 (45%), Gaps = 58/283 (20%)

Query: 340 GPPGCKGDPGN----------RGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGA 389
           GP G KG+ G            GP G  G AG  G  G QG  G  G PG RGPPG    
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 327

Query: 390 KGSKGYQGNSGAPGSPGVK-----GAKGGPGPRGP--------------KGEPGRRGDPG 430
               G  G+ GAPG PG           G G +GP              +     RG PG
Sbjct: 328 ----GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383

Query: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRG 490
             G  G  GP G+ G PG             KG  GD G  GPRGPQG  G PGK G RG
Sbjct: 384 PMGYTGRPGPLGQPGSPGL------------KGESGDLGPQGPRGPQGLTGPPGKAGRRG 431

Query: 491 DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550
             G  G RG  G PG KGD G     + G  G PGEKG  G  G +G      L G PG 
Sbjct: 432 RAGADGARGMPGDPGVKGDRG-----FDGLPGLPGEKGHRGDTGAQG------LPGPPGE 480

Query: 551 KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            GE+G+  + GP G PG  GPRG+ GP+G PG PG PG+   D
Sbjct: 481 DGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 523



 Score =  129 bits (325), Expect = 9e-30
 Identities = 84/237 (35%), Positives = 101/237 (42%), Gaps = 65/237 (27%)

Query: 417 RGPKGEPGR-----RGDPGTKGSPGSDGPKGEKGD-------------PGPEGPRGLAGE 458
           R P+ +P R       +P ++ + G  G KGEKG+             PGPEGP GL G 
Sbjct: 246 RSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGP 305

Query: 459 VGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA----------------------- 495
            G +G  G  G PG RGP G  G PG  G+ G PG +                       
Sbjct: 306 PGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEA 365

Query: 496 -----------------GPRGDSGQPGPKGDPGRPG-------FSYPGPRGAPGEKGEPG 531
                            GP G +G+PGP G PG PG           GPRG  G  G PG
Sbjct: 366 QAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPG 425

Query: 532 PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G  G  G  G +G PG  G KG+    G PG PG +G RG  G +G PGPPG+ G
Sbjct: 426 KAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482



 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 46/108 (42%), Positives = 54/108 (50%), Gaps = 15/108 (13%)

Query: 242  AYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG 301
            A GE      + + GP G +G +G +G  G  G PG+   KG  G PG  GPIG  GP G
Sbjct: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ---KGEMGIPGASGPIGPGGPPG 1355

Query: 302  VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG 349
            +PG  G KG  GA G    PG        G KG+ G  GPPG  G PG
Sbjct: 1356 LPGPAGPKGAKGATG----PG--------GPKGEKGVQGPPGHPGPPG 1391


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  323 bits (827), Expect = 5e-88
 Identities = 183/399 (45%), Positives = 210/399 (52%), Gaps = 64/399 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP GP G+ G KG  G  G+ G PG  G++G+ G +G  G PGP GV G +G  GE G
Sbjct: 878  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937

Query: 314  A------------DGRKGAPGLAGKNGTDGQKGKLG---RIGPPGCKGDPG--------- 349
                          G +G PG AGK GT G  G  G   + GP G +G PG         
Sbjct: 938  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997

Query: 350  ------NRGPDGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSG 400
                  N GP G PG AGSPGERG  G  G    PGRPG +GPPG  G KG  G +G  G
Sbjct: 998  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 1057

Query: 401  APGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG 460
              G  GV+G  G PGP GP G  G  GD G  G PG  G KG KG+ GP GP G  G VG
Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVG 1117

Query: 461  NKGAKGDRGLPGPRGPQGALGEPGKQGSRGD------------PGDAGPRGDSGQPGPKG 508
              GA G  G PG RGPQG  G  G +G+RG             PG +G +G++G  GP G
Sbjct: 1118 QPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMG 1177

Query: 509  DPGRPGFSYP-GPRGA---------------PGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552
             PG PG   P GP GA               PGEKGEPG  G  G +G+ G+KG  G +G
Sbjct: 1178 PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERG 1237

Query: 553  EKGEPADPGPPGEPGPRGPRGVPGPEGEPGP---PGDPG 588
            EKGE   PG PG PGP+GP G  GP+G PGP   PGDPG
Sbjct: 1238 EKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1276



 Score =  306 bits (784), Expect = 5e-83
 Identities = 173/362 (47%), Positives = 197/362 (54%), Gaps = 32/362 (8%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGP------KGVPGFKGE 308
            PGP GP G  GQ GA G  GEPG  G +G  G  G EG  GF GP      +G+PG  GE
Sbjct: 1107 PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGE 1166

Query: 309  KGEFGADGRKGAPGL------AGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGE 359
            KGE G  G  G PG       AG NG DG +G    +G +GPPG KG+PG  G  G  GE
Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1226

Query: 360  AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
             G  G RG++G KG+ G+PG  GPPG  G  G  G +GN G  G PG  G  G  GPRG 
Sbjct: 1227 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1286

Query: 420  KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN------KGAKGDRGL--- 470
             G  G RG+ G  G PGS GP GE G PGP G RG AG  G+      KGAKGD G    
Sbjct: 1287 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGA 1346

Query: 471  ---PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEK 527
                GP GP G  G+PG  G RG PG  G +G  G  G  G PG  G     P G PG +
Sbjct: 1347 PGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVG-----PPGLPGLR 1401

Query: 528  GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            G+ G +G +G  G  GL G PG +GEKG+   PGP G PG +G  G+PG  G  GP G P
Sbjct: 1402 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1461

Query: 588  GL 589
            GL
Sbjct: 1462 GL 1463



 Score =  303 bits (777), Expect = 3e-82
 Identities = 164/343 (47%), Positives = 184/343 (53%), Gaps = 11/343 (3%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KGEF 312
            GP G  G +G  GA G  G PGE G  G  G  G++GP+G PGP G PG  GE   KGE 
Sbjct: 1030 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEV 1089

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG---DPGNRGPDGYPGEAGSPGERGDQ 369
            G  G+KG  G  G++G  G  G +G +G PG  G   +PG RGP G+ G  G  G RG  
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFN 1149

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP 429
            G  G  G  G  GP GE G  G  G  G  G PG  G  G  G  GP+GP G  G  G P
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPP 1209

Query: 430  GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP---QGALGEPGKQ 486
            G KG PG  G  G +G+PG +GPRG  GE G  G  G+ G PGP+GP    G  G PG  
Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV 1269

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKG 546
            G  GDPG  G  G  GQ G KGD G  G   PG  G+PG  GE GP GP G RG  G  G
Sbjct: 1270 GFPGDPGPPGEGGPRGQDGAKGDRGEDG--EPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1327

Query: 547  EPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
              GR+G KG   DPG  G PG  GP G  GP G+PGP G  GL
Sbjct: 1328 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGL 1370



 Score =  301 bits (771), Expect = 2e-81
 Identities = 168/389 (43%), Positives = 199/389 (51%), Gaps = 61/389 (15%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G  G  G  G  G  G +G  GDPG++G  GF G  G+PG KG +G+ GA 
Sbjct: 520 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 579

Query: 316 GRKGAPGLAGKNGTDGQ------------KGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
           G  G PG  G+ G DG+            +G LG  GPPG  G PG RG DG  G  GS 
Sbjct: 580 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 639

Query: 364 GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
           G +G+ G  G  G PG +G PG  GA G  G +G  G PG PG+      PG  GP G P
Sbjct: 640 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM------PGSDGPPGHP 693

Query: 424 GRRGDPGTKGSPGSDGPKGEKGDPGPEGPR---GLAGEVGNKGAKGDRGLPGPRGPQGAL 480
           G+ G PGTKG+ G  GP+G  G PGP G +   G+ G  G+KG KG+ G PG +G  G  
Sbjct: 694 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 753

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-------------------------F 515
           G+ G+ G  G  G+ GP G  G+ GP GDPG PG                          
Sbjct: 754 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL 813

Query: 516 SYPGPRGAPGEK------------GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            +PG  GA GEK            GE GP GP G RG  G  G+ G KG  G     GPP
Sbjct: 814 GFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 873

Query: 564 GE---PGPRGPRGVPGPEGEPGPPGDPGL 589
           GE   PGP+GP G PGP+G PGPPG  GL
Sbjct: 874 GERGLPGPQGPNGFPGPKGPPGPPGKDGL 902



 Score =  301 bits (771), Expect = 2e-81
 Identities = 165/381 (43%), Positives = 208/381 (54%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGFPGPKGV---PG 304
            +PGP+GP G  G+ G KG +G+PG+ G KG +G+      PG  GP+G PG  G    PG
Sbjct: 1070 LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPG 1129

Query: 305  FKGEKGEFGADGRKGAP---------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNR---- 351
             +G +G FGA G +G           GL G  G  G+KG+ G +GP G  G PG R    
Sbjct: 1130 ARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAG 1189

Query: 352  -----GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG 406
                 GP G PG  G+ G  G++G  G+ G PG +G PG  G +G +G +G SG PG PG
Sbjct: 1190 PNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1249

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G KG  G  GPKG PG  G PG  G PG  GP+G+ G  G  G  G  G+ G+ G  G
Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1309

Query: 467  DRGLPGPRGPQGALGEPGKQ------GSRGDP---------GDAGPRGDSGQPGPKGDPG 511
            + G PGP G +G  G PG +      G++GDP         G  GP G +G+PGP G  G
Sbjct: 1310 ENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRG 1369

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GL+G+ G KGEKG P      GPPGE G 
Sbjct: 1370 LPG--SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1427

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PGP+G PG  G+ G+
Sbjct: 1428 KGDRGLPGPQGSPGQKGEMGI 1448



 Score =  298 bits (764), Expect = 1e-80
 Identities = 168/365 (46%), Positives = 195/365 (53%), Gaps = 38/365 (10%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG---------PIGFPGPKG--- 301
           IPGP G +G  G +G KG++G  GEPG  G+QG PG +G         P G  GP+G   
Sbjct: 620 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG 679

Query: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
           +PG  G  G  G  G++G PG  G  G  G +G LG  GP G KG  G RG  G+ GE G
Sbjct: 680 LPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 739

Query: 362 S---PGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG----- 413
               PG +GD G KGD G  G  G  GE G +G KG  G +G PG PG+ G KG      
Sbjct: 740 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799

Query: 414 ----PGPRGPKGE------PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463
               PG +GPKG       PG  G+ G +G  G  GP+GE+G  GP G RG  G  G  G
Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSG 859

Query: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523
           AKG  G  GP GP G  G PG QG  G PG  GP      PGP G  G PG  +PG RG 
Sbjct: 860 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP------PGPPGKDGLPG--HPGQRGE 911

Query: 524 PGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            G +G+ GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP
Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGP 971

Query: 584 PGDPG 588
           PG PG
Sbjct: 972 PGAPG 976



 Score =  298 bits (762), Expect = 2e-80
 Identities = 170/390 (43%), Positives = 195/390 (50%), Gaps = 52/390 (13%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            GP G  G  G  G+ G  G PG+   PG KG QG  G +GP+G+PGP+GV G  G +G  
Sbjct: 673  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLK 732

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP------GER 366
            G  G KG  G  G  G  G KG  G +G PG +G+ G  GP G  G  G P      GE+
Sbjct: 733  GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEK 792

Query: 367  GDQGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
            G  G  G PG PGR+GP      PG  GA G KG +G SG  G  G +G  G  G RGP+
Sbjct: 793  GKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPR 852

Query: 421  GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGL---------------------AGEV 459
            G  G+ G  GT G  G  GP GE+G PGP+GP G                       GEV
Sbjct: 853  GATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEV 912

Query: 460  GNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQP------GPKGDPGRP 513
            G +G  G  G PG  GPQGA GE G  G RG PG  GP G+ G P      G KGDPG P
Sbjct: 913  GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972

Query: 514  GF----------SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            G            +PG RG PG  G PG +G EG  G  G  G PG +G  G     GPP
Sbjct: 973  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 1032

Query: 564  GEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            G PGP+GP G  G +G PG  G  G T  D
Sbjct: 1033 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 1062



 Score =  295 bits (754), Expect = 2e-79
 Identities = 161/359 (44%), Positives = 189/359 (52%), Gaps = 32/359 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG--- 310
            +PG +G  G +G +G  G  G  G PG++G  G  G  GP G PGP+G PG  GEKG   
Sbjct: 992  LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051

Query: 311  ---------EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
                       G  G  G PG AG  G  G+ G  G +G PG KG  GN+G  G PG  G
Sbjct: 1052 EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1111

Query: 362  SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---------KGAKG 412
              G  G  G  G  G PG RGP G  GAKG +G +G +G PG  G+         KG  G
Sbjct: 1112 PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171

Query: 413  GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPG 472
              GP GP G PG RG  G  G+ G  GP G  G+ GP G +G  GE G+ G +G+ G+ G
Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1231

Query: 473  PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGP 532
            PRG +G  GE G+ G  G PG  GP GD    GPKG+PG  GF      G PG  GE GP
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDD---GPKGNPGPVGFP-----GDPGPPGEGGP 1283

Query: 533  RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE---PGPPGDPG 588
            RG +G +GD G  GEPG+ G  G   + GPPG  G RGP G PG EG     G  GDPG
Sbjct: 1284 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPG 1342



 Score =  293 bits (749), Expect = 6e-79
 Identities = 164/372 (44%), Positives = 193/372 (51%), Gaps = 41/372 (11%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG------VPGFKGEK 309
            G  GP+G +G+ G  G+ G PG  G+KG+ G PG+ G  G  GPKG       PG  GEK
Sbjct: 766  GEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEK 825

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ 369
            G  G  G+ G  G  G  G  GQ+G  G  G  G KG  G  GP G PGE G PG +G  
Sbjct: 826  GARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPN 885

Query: 370  G---GKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG------------P 414
            G    KG PG PG+ G PG  G +G  G+QG +G PG PGV G +G             P
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 415  GPRGPKGEPG---------RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAK 465
            GP GP GE G          +GDPG  G+PG DGP G +G PG  G  G AG  G KG +
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005

Query: 466  GDRGLPGPRGPQ---------GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
            G  G PGP G           G +G PG+ G +G PG AG +G  G+ GP G  GR G  
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 517  YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576
              GP G PG  G PG  G +G +G+ G  G+ G KG KGE   PGPPG  GP G  G  G
Sbjct: 1066 --GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1123

Query: 577  PEGEPGPPGDPG 588
             +GEPG  G  G
Sbjct: 1124 ADGEPGARGPQG 1135



 Score =  290 bits (741), Expect = 5e-78
 Identities = 159/358 (44%), Positives = 190/358 (53%), Gaps = 26/358 (7%)

Query: 256  GPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            GP GP GY   RG KG  G  G  G  G+KG  G PG +G IG  G +G  G  G +GE 
Sbjct: 709  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 768

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG---YPGEAGSPGERGDQ 369
            G +G KG  G  G  G  G  G+ G++G PG  G PG +GP G   +PG  G+ GE+G +
Sbjct: 769  GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 828

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS---------------PGVKGAKGGP 414
            G  G  G  G RGP G  G +G +G  G SGA G+               PG +G  G P
Sbjct: 829  GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG---PRGLAGEVGNKGAKGDRGLP 471
            GP+GP G PG+ G PG  G  G  G +G+ G PGP G   P+G AGE G  G +G  G P
Sbjct: 889  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 948

Query: 472  GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPG 531
            GP G QG  G  GK+G++GDPG  G  G  G  G +G PG  G   PG  G PG KG  G
Sbjct: 949  GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL--PGTAGGPGLKGNEG 1006

Query: 532  PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
            P GP G  G  G +G  G  G  G P  PGP G PG  G +GVPG +G  GP G  G+
Sbjct: 1007 PSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064



 Score =  288 bits (738), Expect = 1e-77
 Identities = 179/419 (42%), Positives = 203/419 (48%), Gaps = 82/419 (19%)

Query: 252  LEIPGPSGPKGY------RGQKGAKGNMGEP------------GEPGQKGRQGDPGIEGP 293
            L  PGP G KG       +G KG KG  G P            GE G  G +G+ G EGP
Sbjct: 714  LGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGP 773

Query: 294  IGFPGP---KGVPGFKGEKGEF------------------------GADGRKGAPGLAGK 326
             G  GP    G PG  GEKG+                         GA G KGA GL+GK
Sbjct: 774  KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 833

Query: 327  N---------GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ---GGKGD 374
            +         G  GQ+G  G  G  G KG  G  GP G PGE G PG +G     G KG 
Sbjct: 834  SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGP 893

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV---KGAKGGPGPRGPKGEPGRRGDPGT 431
            PG PG+ G PG  G +G  G+QG +G PG PGV   +GA G  GP G +G PG  G PG 
Sbjct: 894  PGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGE 953

Query: 432  KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGD 491
            +G PG+ G +G KGDPGP G  G  G  G +G  G+RGLPG  G  G  G  G  G  G 
Sbjct: 954  QGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGP 1013

Query: 492  PGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------------PGP 532
             G  G RG +G  GP G PGRPG   P    G +G PGEKG                PGP
Sbjct: 1014 AGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGP 1073

Query: 533  RGPEGGRGDFGLKGE---PGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             GP G  G+ G KGE   PG+KG KG   + GPPG PGP GP G PG  G  G PG  G
Sbjct: 1074 AGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARG 1132



 Score =  278 bits (710), Expect = 2e-74
 Identities = 161/350 (46%), Positives = 187/350 (53%), Gaps = 31/350 (8%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKG---------NMGEPGEPGQKGRQGDPGIEGPI 294
            GE   V  +  PGP GP+G  G  GA G         N+G PGE G+ G  G PGI+G  
Sbjct: 1168 GETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE- 1226

Query: 295  GFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPD 354
              PG KG  G +GEKGE G  G  G PG  G  G DG KG  G +G PG  G PG  GP 
Sbjct: 1227 --PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP- 1283

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
                  G  G +GD+G  G+PG+PG  GP GE G  G  G +G +G+PGS G +G KG  
Sbjct: 1284 -----RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGA- 1337

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
                 KG+PG  G PG  G  G  GP G+   PGP+G RGL G VG +G  G  G  GP 
Sbjct: 1338 -----KGDPGAIGAPGKTGPVGPAGPAGK---PGPDGLRGLPGSVGQQGRPGATGQAGPP 1389

Query: 475  GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGE---P 530
            GP G  G PG +G  G  G+ G  G  G  GP G+ G  G    PGP+G+PG+KGE   P
Sbjct: 1390 GPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIP 1449

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
            G  GP G  G  GL G  G KG KG     GP GE G +GP G PGP GE
Sbjct: 1450 GASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGE 1499



 Score =  271 bits (693), Expect = 2e-72
 Identities = 161/389 (41%), Positives = 192/389 (49%), Gaps = 60/389 (15%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G  G  G +GN G  G+PG++G  G  G+ G  G PGP G       +  FG+
Sbjct: 401 PGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR--FGS 458

Query: 315 DGRKGAPGLAGKNGTDG---QKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            G    P +A +        Q+ +L   GPPG  G  G  GP G PG  G  GE GD G 
Sbjct: 459 GGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGP 518

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
           +G  G  G  GPPG+ G +G  G  G  G PG PGVKG +G  G  G  GE G RGD G 
Sbjct: 519 QGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578

Query: 432 KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK---GAKGDRGLPGP--------------- 473
           +G PG  G  GE+GD G  GPRGL GE G +   G KG  G+PGP               
Sbjct: 579 QGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGS 638

Query: 474 RGPQGALGEPGKQGSRGDPGDAGPR---GDSGQPGPKGDPGRPGF-------SYPGPRGA 523
            GPQG  G PG+QG+ G  G  GP+   G  G+ GP+G PG PG         +PG  G 
Sbjct: 639 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGP 698

Query: 524 PGEKGEPGPRGPEG--------------------------GRGDF-GLKGEPGRKGEKGE 556
           PG KG  GP GP+G                          G   F G KG+ G KG++GE
Sbjct: 699 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGE 758

Query: 557 PADPGPPGEPGPRGPRGVPGPEGEPGPPG 585
              PG  GE GP GP+G  GP G+PGPPG
Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPG 787



 Score =  219 bits (557), Expect = 1e-56
 Identities = 136/334 (40%), Positives = 163/334 (48%), Gaps = 68/334 (20%)

Query: 298 GPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYP 357
           GP+G+ G KGE            PG+  + G  G +G  G IGPPG +G+PG   P G P
Sbjct: 377 GPRGLKGEKGEPAVL-------EPGMLVE-GPPGPEGPAGLIGPPGIQGNPG---PVGDP 425

Query: 358 GEAGSPGERGDQGGKGDPGRPGR------------------------------------- 380
           GE G PG  G  G  G PG PG                                      
Sbjct: 426 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 485

Query: 381 RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP 440
           RGPPG +G  G  G  G  G+PG  G  G  G  GPRGP+G  G  G  G +G  G+DG 
Sbjct: 486 RGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGA 545

Query: 441 KGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGD 500
           +G  GDPG +G RG  G  G  G KG RG     G QG  G PG+ G RGD G+ GPRG 
Sbjct: 546 RGMPGDPGVKGDRGFDGLPGLPGEKGHRG---DTGAQGLPGPPGEDGERGDDGEIGPRGL 602

Query: 501 SGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEP 557
            G+ GP+G          GP+G PG  G PG RG   P+G +G  G +GEPG  G++G P
Sbjct: 603 PGESGPRG--------LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTP 654

Query: 558 ADPGPPGEPGPR---GPRGVPGPEGEPGPPGDPG 588
              G  G PGP+   GP G  GP+G+PG PG PG
Sbjct: 655 ---GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685



 Score =  180 bits (456), Expect = 5e-45
 Identities = 123/331 (37%), Positives = 143/331 (43%), Gaps = 62/331 (18%)

Query: 292 GPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN- 350
           G  G   P+G   +    G+   +  +  P L+ +    G        GP G KG+ G  
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAH----GPRGLKGEKGEP 388

Query: 351 ---------RGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGA 401
                     GP G  G AG  G  G QG  G  G PG RGPPG        G  G+ GA
Sbjct: 389 AVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA------GLPGSDGA 442

Query: 402 PGSPGVK-----GAKGGPGPRGP--------------KGEPGRRGDPGTKGSPGSDGPKG 442
           PG PG           G G +GP              +     RG PG  G  G  GP G
Sbjct: 443 PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG 502

Query: 443 EKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSG 502
           + G PG             KG  GD G  GPRGPQG  G PGK G RG  G  G RG  G
Sbjct: 503 QPGSPGL------------KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 550

Query: 503 QPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP 562
            PG KGD G     + G  G PGEKG  G  G +G      L G PG  GE+G+  + GP
Sbjct: 551 DPGVKGDRG-----FDGLPGLPGEKGHRGDTGAQG------LPGPPGEDGERGDDGEIGP 599

Query: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            G PG  GPRG+ GP+G PG PG PG+   D
Sbjct: 600 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMD 630



 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 46/108 (42%), Positives = 54/108 (50%), Gaps = 15/108 (13%)

Query: 242  AYGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG 301
            A GE      + + GP G +G +G +G  G  G PG+   KG  G PG  GPIG  GP G
Sbjct: 1406 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ---KGEMGIPGASGPIGPGGPPG 1462

Query: 302  VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG 349
            +PG  G KG  GA G    PG        G KG+ G  GPPG  G PG
Sbjct: 1463 LPGPAGPKGAKGATG----PG--------GPKGEKGVQGPPGHPGPPG 1498


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  321 bits (823), Expect = 2e-87
 Identities = 182/385 (47%), Positives = 213/385 (55%), Gaps = 49/385 (12%)

Query: 255  PGPSGPKGYRGQKGAKGNMG------EPGEPGQKGRQGDPGIEGPIGFPG---PKGVPGF 305
            PGP+GP G RG++GA G  G       PG PG+ G+ GD G+ G  G PG   P+G  GF
Sbjct: 644  PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 703

Query: 306  KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE---AGS 362
             GE+G  GA G +G  GL G  GTDG KG  G  GPPG +G PG +G  G  G    AG 
Sbjct: 704  PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 763

Query: 363  PGERGDQGGKGDPGRPGRR---------GPPGEIGAKGSKGY------QGNSGAPGSPGV 407
             G+RGD G KG  G PG+          GPPG  GA G KG        G++GA G+PG 
Sbjct: 764  KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 823

Query: 408  KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE------GPRGLAGEVGN 461
            +G  G PGP G  G PG  G PG KG  G  G KG+ G PGP+      GP+G  G  G 
Sbjct: 824  RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 462  KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPK---GDPGRPGFS-- 516
            KGA+G +G PG  G  GA G  G  GS G+PG  GP G SG+ GPK   GD G PG +  
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 517  --YPGPRGAPGEKGEP---------GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
                GP G PGEKGEP         GP GP+G  G  G+ G PG++GE+G P  PGP GE
Sbjct: 944  PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 1003

Query: 566  PGPRGPRGVPGPEGEPGPPGDPGLT 590
            PG +G  G  G  G PGP G PGLT
Sbjct: 1004 PGKQGAPGASGDRGPPGPVGPPGLT 1028



 Score =  315 bits (806), Expect = 1e-85
 Identities = 177/411 (43%), Positives = 213/411 (51%), Gaps = 76/411 (18%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           + GP GP+G  G  G  G+ GE G+PG+ G +G PG +G  GFPG  G+PG KG +G  G
Sbjct: 235 VSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPG 294

Query: 314 ADGRKG---APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP---------DGYPGEAG 361
            DG KG   APG+ G++G+ G+ G  G +GP G  G+ G  GP         DG PG AG
Sbjct: 295 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAG 354

Query: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG--------------- 406
            PG  G  GG G PG PG +G  G  GA+G +G QG  G PG+PG               
Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 414

Query: 407 ------------VKGAKGGPGPRGPKGEPG---------RRGDPGTKGSPGSDGPKGEKG 445
                       + GA G PGPRGP G  G         + G+PG  G  G  GPKGE G
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 474

Query: 446 DPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQ---------------GSRG 490
             GP+G  G AGE G +GA+G+ G  GP GP G  G PG +               G RG
Sbjct: 475 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 534

Query: 491 DPGDAGPRGDSGQPGPKGDP---------GRPGFSYP----GPRGAPGEKGEPGPRGPEG 537
             G AGP+G +G PG  G+P         GRPG + P    GP GAPGE G PGP GP+G
Sbjct: 535 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 594

Query: 538 GRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            RG  G+ G PG KG  GEP   G  G PG  G RG+PG +GE G  G PG
Sbjct: 595 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645



 Score =  308 bits (790), Expect = 1e-83
 Identities = 166/370 (44%), Positives = 196/370 (52%), Gaps = 38/370 (10%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  G  G  G  G +G  G PG+PG  G  G PG  G  G PGP+G  GF G  G  G 
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV 286

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            G +G PGL G  G  G  G  G  G PG  G PG  GP G PGE G  G  G  G +G+
Sbjct: 287 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346

Query: 375 PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP---GT 431
            G+PG  GPPG +G  G  G+ G  GA G  G  GA+G  G +GP+GEPG  G P   G 
Sbjct: 347 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 406

Query: 432 KGSPGSD------------------------GPKGEKGDPGPEGPRGLAGE---VGNKGA 464
            G+PG+D                        GP G +G  GP GP+G  GE    G KG 
Sbjct: 407 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE 466

Query: 465 KGDRGLPGPRGPQGA---LGEPGKQGSRGDPGDA---GPRGDSGQPGPKGDPGRPGFSYP 518
           +G +G PGP GPQGA    GE GK+G+RG+PG     GP G+ G PG +G PG+ G +  
Sbjct: 467 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA-- 524

Query: 519 GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE 578
           GP+GAPGE+G  G  GP+G  GD G  GEPG  G +G    PG  G  G  GP G PG +
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584

Query: 579 GEPGPPGDPG 588
           G PGPPG  G
Sbjct: 585 GRPGPPGPQG 594



 Score =  306 bits (785), Expect = 4e-83
 Identities = 176/370 (47%), Positives = 202/370 (54%), Gaps = 37/370 (10%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPG---QKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           PG  GP G  G KGA G+ G PGEPG    +G  G PG  GP G  GP G PG  G  G 
Sbjct: 530 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 312 FGADGRKGAPGLAG------KNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY---PGEAGS 362
            G  G +G PG+ G       NG  G+ G+ G  G PG +G PG  G  G    PG AG 
Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649

Query: 363 PGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
            GERG+QG  G     G PG  GPPGE G  G +G  G +GAPG  G +G +G PG RG 
Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709

Query: 420 KGEPGRRGDPGTKGSPGSDGPKGEK---GDPGPEGPRGLAGEVGNKGA------KGDRGL 470
            G  G +G  G  G+PG+DGPKG     G PG +GP GL G  G +GA      KGDRG 
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769

Query: 471 PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGE 529
            G +GP+GA   PGK G RG  G  GP G +G  G KG+ G PG     G RGAPGE+GE
Sbjct: 770 VGEKGPEGA---PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826

Query: 530 PGPRGPEGGRGDFGLKGEPGRKGEKGE---------PADPGPPGEPGPRGPRGVPGPEGE 580
            GP GP G  G  G  G+PG KGE+GE         P   GP G PGP+GP GV GP+G 
Sbjct: 827 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 886

Query: 581 PGPPGDPGLT 590
            G  G PG T
Sbjct: 887 RGAQGPPGAT 896



 Score =  305 bits (780), Expect = 1e-82
 Identities = 175/392 (44%), Positives = 202/392 (51%), Gaps = 59/392 (15%)

Query: 256  GPSGPKGYRGQKGAKGN---MGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            GP GP G+ G  GA G     GE GE GQKG  G PG +GP G PGP+G  G  G KG  
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 313  GADGRKGA---------------------PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR 351
            GA G  GA                     PG  G +G DG KG  G  GPPG  G+PG +
Sbjct: 888  GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 947

Query: 352  GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAP--------- 402
            GP G PGE G PG+ G  G +G PG  G  G  G +G  G +G +G  G P         
Sbjct: 948  GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 1007

Query: 403  GSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G+PG  G +G PGP GP G  G  G+PG +GSPG+DGP G  G  G +G RG  G VG  
Sbjct: 1008 GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067

Query: 463  GAKGDRGLPGPRGP------------QGALGEPGKQGSRGDPGDAGPRGD---SGQPGPK 507
            GA G  G PGP GP            QG +G  G  G+RG  G  GPRGD   +G+PG +
Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1127

Query: 508  GDPGRPGFS----YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            G  G  GF+     PGP G  G++G  GP GP G RG  G  G  G+ G  G P   GPP
Sbjct: 1128 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187

Query: 564  ------GEPGPRGPRGVPGPEGEPGPPGDPGL 589
                  GE GP GP G PGP G PGPPG PG+
Sbjct: 1188 GPRGRSGETGPAGPPGNPGPPGPPGPPG-PGI 1218



 Score =  304 bits (778), Expect = 3e-82
 Identities = 184/429 (42%), Positives = 213/429 (49%), Gaps = 98/429 (22%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQ------------------KGRQGDPGIEGPIGFP 297
           G +GP G RG +GA+G  GEPG PG                   KG  G PGI G  GFP
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434

Query: 298 GPKGVPG---------------------FKGE---KGEFGADGRKGAPGLA---GKNGTD 330
           GP+G PG                     FKGE   KGE G  G +GAPG A   GK G  
Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494

Query: 331 GQKGKLGRIGPPGCKGDPGNR---------GPDGYPGEAGSPGERGDQGGKGDPGRPGR- 380
           G+ G +G IGPPG +G PGNR         GP G PGE G  G  G +G  GDPGRPG  
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 381 --------------RGPPGEIGAKGSKGYQGNSGAPGSPGVK---GAKGGPGPRGPKGEP 423
                          GP G++G  G+ G  G  G PG  G +   G  G PGP+G  GEP
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614

Query: 424 GRRGD------PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477
           G+ G+      PG +G PG DG  G  G PGP GP G  GE G  G  G +GLPGP GP 
Sbjct: 615 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 478 GALGEPGKQGSRGD---PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAP------GEKG 528
           G  G+PG QG  G+   PG  GPRG+ G PG +G PG  G    GPRG P      G KG
Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ--GPRGLPGTPGTDGPKG 732

Query: 529 EPGPRGPEGGRGDFGLKGEPGR---------KGEKGEPADPGPPGEPGPRGPRGVPGPEG 579
             GP GP G +G  GL+G PG          KG++G+  + GP G PG  G RG+ GP G
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792

Query: 580 EPGPPGDPG 588
            PGP G  G
Sbjct: 793 PPGPAGANG 801



 Score =  303 bits (775), Expect = 6e-82
 Identities = 167/359 (46%), Positives = 198/359 (55%), Gaps = 28/359 (7%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG +GP+G  G  GA G  G PG PG +G +G PG+   +GFPGPKG  G  G+ GE G 
Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV---MGFPGPKGANGEPGKAGEKGL 622

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY---PGEAGSPGERG---D 368
            G  G  GL GK+G  G  G  G  GP G +G+ G  GP G+   PG  G PGE G   D
Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682

Query: 369 QGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP--- 419
           QG  G+ G PG  GP      PGE G+ G++G QG  G PG+PG  G KG  GP GP   
Sbjct: 683 QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA 742

Query: 420 KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGA 479
           +G PG +G PG +G+ G  GPKG++GD G +GP G  G+ G +G  G  G PGP G  G 
Sbjct: 743 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 802

Query: 480 LGE---PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGE------ 529
            GE   PG  GS G  G  G RG++G PGP G  G PG    PG +G  GE G+      
Sbjct: 803 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 862

Query: 530 PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           PGP+GP G  G  G  G  G KG +G    PG  G PG  G  G PG  G PGPPG PG
Sbjct: 863 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921



 Score =  301 bits (771), Expect = 2e-81
 Identities = 174/389 (44%), Positives = 201/389 (51%), Gaps = 55/389 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G +G +G +G+ GE G PG +GR G+PG  G  G PGP G PG  G  G F A
Sbjct: 122 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181

Query: 315 D------------------------GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN 350
                                    G +G PG AG  G  G +G  G  G PG  G  G 
Sbjct: 182 QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 241

Query: 351 RGPDGYP------GEAGSPGERGD------QGGKGDPGRP------GRRGPPGEIGAKGS 392
           RGP G P      GEAG PG+ G+      QG +G PG P      G RG PG  GAKG 
Sbjct: 242 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 301

Query: 393 KGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP 452
            G  G  G  GSPG  G+ G  GPRG  GE GR G  G  G+ G+DG  G  G PGP GP
Sbjct: 302 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 361

Query: 453 RGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ---PGPKGD 509
            G  G  G  GAKG+ G  G RGP+GA G  G+ G+ G PG AG  G+ G    PG KG 
Sbjct: 362 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 421

Query: 510 PGRPGFS----YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
            G PG +    +PGPRG PG +G  GP GP+G  G+ G+ G  G +G KGEP   GP G 
Sbjct: 422 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 481

Query: 566 PGP------RGPRGVPGPEGEPGPPGDPG 588
           PGP      RG RG PG  G  GPPG+ G
Sbjct: 482 PGPAGEEGKRGARGEPGGVGPIGPPGERG 510



 Score =  295 bits (756), Expect = 9e-80
 Identities = 166/362 (45%), Positives = 186/362 (51%), Gaps = 41/362 (11%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KG 310
            +PG  G  G  G KG +G++GE G  G  G+ G  G+ GPIG PGP G  G KGE    G
Sbjct: 751  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 810

Query: 311  EFGADGRKGAPG------------LAGKNGTDGQKGKLGRIGPPGCKGD---PGNRGPDG 355
              G+ G +GAPG             AG  G DGQ G  G  G  G KGD   PG +GP G
Sbjct: 811  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 870

Query: 356  YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPG 415
             PG  G  G  G +G +G  G PG  G PG  G  G  G  GN G PG PG  G  G  G
Sbjct: 871  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930

Query: 416  PRGPKGEPGRRGDPGT---------KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
             RG  G PGR G+PG          KG PG DGP G +G PGP+G  G  G VG  G +G
Sbjct: 931  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 990

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGE 526
            +RG PG  GP    GEPGKQG+ G  GD GP      PGP G PG       GP G PG 
Sbjct: 991  ERGFPGLPGPS---GEPGKQGAPGASGDRGP------PGPVGPPG-----LTGPAGEPGR 1036

Query: 527  KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
            +G PG  GP G  G  G+KG+ G  G  G P  PGPPG PGP GP G  G  GE G  G 
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1096

Query: 587  PG 588
             G
Sbjct: 1097 MG 1098



 Score =  289 bits (740), Expect = 6e-78
 Identities = 177/425 (41%), Positives = 205/425 (48%), Gaps = 91/425 (21%)

Query: 255  PGPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGI------EGPIGFPGPKGV 302
            PGP GP+G RGQ G       KG  GEPG+ G+KG  G PG+      +G  G  GP G 
Sbjct: 587  PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 646

Query: 303  PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG---NRGPDGYPGE 359
             G  GE+GE GA G  G  GL G  G  G+ GK G  G PG  G PG    RG  G+PGE
Sbjct: 647  AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706

Query: 360  AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
             GSPG +G QG +G PG PG  GP G  G  G  G QG  G  G PG +GA G  GP+G 
Sbjct: 707  RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766

Query: 420  KGEPGRRGDPGTKGS------------PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
            +G+ G +G  G  G             PG  G  GEKG+ GP GP G AG  G  G +G+
Sbjct: 767  RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826

Query: 468  RGLPGPRG---------PQGALGEPGKQGSRGDPGDAGPRGDSGQPGP------------ 506
             G PGP G           GA GE G+ G +GD G  GP+G SG PGP            
Sbjct: 827  TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 886

Query: 507  ---KGDPGRPGF-------------SYPGPRGAPGEKGEPGPR------GPEGGRGDFGL 544
               +G PG  GF               PGP G PG  G+ GP+      GP G  G+ GL
Sbjct: 887  RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946

Query: 545  KGEPGRKGEKGEPADPGPPGEPGPRGPR---------------------GVPGPEGEPGP 583
            +G  G  GEKGEP D GP G  GP GP+                     G+PGP GEPG 
Sbjct: 947  QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006

Query: 584  PGDPG 588
             G PG
Sbjct: 1007 QGAPG 1011



 Score =  288 bits (737), Expect = 1e-77
 Identities = 178/409 (43%), Positives = 198/409 (48%), Gaps = 70/409 (17%)

Query: 255 PGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           PGP GP+G    RG+ G  G  G  G  GQ G  G PG  GP G PG  G PG KGE G 
Sbjct: 320 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 379

Query: 312 FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            GA G +GA G  G+ GT G  G  G  G PG  G PG +G  G PG AG+PG  G +G 
Sbjct: 380 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG------------- 418
            G  G  G  GP G+ G  G  G++G  G  G PG  G +G PGP G             
Sbjct: 440 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 499

Query: 419 --PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG------------EVGNKGA 464
             P G PG RG PG +G PG DG  G KG PG  GP GLAG            E G  GA
Sbjct: 500 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559

Query: 465 KGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPG------PKGDPGRPGFS-- 516
           +G  G PG  GPQG +G  G  G  G PG  GP+G  GQPG      PKG  G PG +  
Sbjct: 560 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 619

Query: 517 -----YPGPRGAPGEKGE------PGPRGPEGGRGDFG---------LKGEPGRKGEKGE 556
                 PG RG PG+ GE      PGP GP G RG+ G         L G PG  GE G+
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679

Query: 557 PADPGPPGEPG------PRGPRGVPGP------EGEPGPPGDPGLTECD 593
           P D G PGE G      PRG RG PG       +G  GP G PG    D
Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 728



 Score =  276 bits (705), Expect = 7e-74
 Identities = 158/362 (43%), Positives = 181/362 (50%), Gaps = 62/362 (17%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEG---PIGFPGPKGVPGFKGE 308
            PGP GP G  G KGA+G  G PG    PG  GR G PG  G   P G PGP G  G KG 
Sbjct: 872  PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---------------- 352
            +G+ G  GR G PGL G  G  G+KG+ G  GP G +G PG +G                
Sbjct: 932  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 353  --------PDGYPGEAGSPGERGDQGGKG------------DPGR---PGRRGPPGEIGA 389
                    P G PG+ G+PG  GD+G  G            +PGR   PG  GPPG  GA
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051

Query: 390  KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449
             G KG +G +GA G+PG  G  G PGP GP G+ G RG+ G +G  G  GP G +G  GP
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1111

Query: 450  EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509
            +GPRG  GE G  G +G +G  G  G QG  G PG  G +G  G AGP G  G PGP   
Sbjct: 1112 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP--- 1168

Query: 510  PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR 569
                     GP G  G  G PGP GP G R      G  G  G  G P +PGPPG PGP 
Sbjct: 1169 --------VGPSGKDGANGIPGPIGPPGPR------GRSGETGPAGPPGNPGPPGPPGPP 1214

Query: 570  GP 571
            GP
Sbjct: 1215 GP 1216



 Score =  213 bits (542), Expect = 6e-55
 Identities = 129/285 (45%), Positives = 146/285 (51%), Gaps = 27/285 (9%)

Query: 255  PGPSGPKGYRG------QKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP G  G RG      Q+G +G  G PG  G+ G+QG PG  G  G PGP G PG  G 
Sbjct: 971  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
             GE    GR+G+PG  G  G DG  G  G  G  G  G PG  GP G PG AG  G++GD
Sbjct: 1031 AGE---PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1087

Query: 369  QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD 428
               +G+ G  G  GP G  GA+G +G QG  G       KG  G PG RG KG  G  G 
Sbjct: 1088 ---RGEAGAQGPMGPSGPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGL 1138

Query: 429  PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
             G  G PG  G +G  G  GP GPRG  G VG  G  G  G+PGP GP      PG +G 
Sbjct: 1139 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP------PGPRGR 1192

Query: 489  RGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG-APGEKGEPGP 532
             G+ G AGP G+ G PGP G PG PG       G  P EKG P P
Sbjct: 1193 SGETGPAGPPGNPGPPGPPGPPG-PGIDMSAFAGLGPREKG-PDP 1235



 Score =  163 bits (412), Expect = 7e-40
 Identities = 108/285 (37%), Positives = 132/285 (46%), Gaps = 48/285 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGE---------PGQKGRQGDPGIEGPIGFPGPKGVPG 304
            +PGPSG  G +G  GA G+ G PG           G+ GR+G PG +GP G  G  GV G
Sbjct: 997  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGK---------LGRIGPPGCKGDPGNRGPDG 355
             +GE G  GA G  G PG  G  G  G++G          +G  GP G +G  G +GP G
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 356  YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG--------- 406
              GEAG PGERG +G +G  G  G  GPPG  G +G+ G  G SG  G PG         
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1176

Query: 407  ---VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD--------PGPEGPRGL 455
               + G  G PGPRG  GE G  G PG  G PG  GP G   D        P  +GP  L
Sbjct: 1177 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1236

Query: 456  --------AGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDP 492
                    AG +    A+ D  L        ++  P  +GSR +P
Sbjct: 1237 QYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSP--EGSRKNP 1279



 Score =  158 bits (400), Expect = 2e-38
 Identities = 96/209 (45%), Positives = 103/209 (49%), Gaps = 24/209 (11%)

Query: 401 APGSPGVKGAKGGPGPR----GPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLA 456
           A G PG KG KG PG      GPKG PG +G  G +G  G  G KGEKG PGP   RG  
Sbjct: 96  ASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP---RGRD 152

Query: 457 GEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDP------------GDAGPRGDSGQP 504
           GE G  G  G  G PGP GP G  G    Q + G              G  GP G  G P
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 505 GPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPG 564
           GP G PG  GF     +G PGE GEPG  GP G RG  G  G+PG  GE G+P   G  G
Sbjct: 213 GPAGAPGPQGF-----QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERG 267

Query: 565 EPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            PGP+G RG PG  G PG  G  G    D
Sbjct: 268 PPGPQGARGFPGTPGLPGVKGHRGYPGLD 296



 Score =  122 bits (305), Expect = 2e-27
 Identities = 83/242 (34%), Positives = 101/242 (41%), Gaps = 16/242 (6%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            G+  +   +  PG  GP G  G  G  G  G+ GE G +G  G  G  G  G  GP+G  
Sbjct: 1056 GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1115

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
            G KGE GE G  G KG  G  G  G           GPPG  GD G  GP      AG  
Sbjct: 1116 GDKGEAGEPGERGLKGHRGFTGLQGLP---------GPPGPSGDQGASGP------AGPS 1160

Query: 364  GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
            G RG  G  G  G+ G  G PG IG  G +G  G +G  G PG  G  G PGP GP  + 
Sbjct: 1161 GPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1220

Query: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
                  G +   G D  +  + D    G R    EV       +  +   R P+G+   P
Sbjct: 1221 SAFAGLGPR-EKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1279

Query: 484  GK 485
             +
Sbjct: 1280 AR 1281


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  321 bits (823), Expect = 2e-87
 Identities = 182/385 (47%), Positives = 213/385 (55%), Gaps = 49/385 (12%)

Query: 255 PGPSGPKGYRGQKGAKGNMG------EPGEPGQKGRQGDPGIEGPIGFPG---PKGVPGF 305
           PGP+GP G RG++GA G  G       PG PG+ G+ GD G+ G  G PG   P+G  GF
Sbjct: 575 PGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGF 634

Query: 306 KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE---AGS 362
            GE+G  GA G +G  GL G  GTDG KG  G  GPPG +G PG +G  G  G    AG 
Sbjct: 635 PGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGP 694

Query: 363 PGERGDQGGKGDPGRPGRR---------GPPGEIGAKGSKGY------QGNSGAPGSPGV 407
            G+RGD G KG  G PG+          GPPG  GA G KG        G++GA G+PG 
Sbjct: 695 KGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE 754

Query: 408 KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE------GPRGLAGEVGN 461
           +G  G PGP G  G PG  G PG KG  G  G KG+ G PGP+      GP+G  G  G 
Sbjct: 755 RGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 462 KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPK---GDPGRPGFS-- 516
           KGA+G +G PG  G  GA G  G  GS G+PG  GP G SG+ GPK   GD G PG +  
Sbjct: 815 KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 517 --YPGPRGAPGEKGEP---------GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
               GP G PGEKGEP         GP GP+G  G  G+ G PG++GE+G P  PGP GE
Sbjct: 875 PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 934

Query: 566 PGPRGPRGVPGPEGEPGPPGDPGLT 590
           PG +G  G  G  G PGP G PGLT
Sbjct: 935 PGKQGAPGASGDRGPPGPVGPPGLT 959



 Score =  315 bits (806), Expect = 1e-85
 Identities = 177/411 (43%), Positives = 213/411 (51%), Gaps = 76/411 (18%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           + GP GP+G  G  G  G+ GE G+PG+ G +G PG +G  GFPG  G+PG KG +G  G
Sbjct: 166 VSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPG 225

Query: 314 ADGRKG---APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP---------DGYPGEAG 361
            DG KG   APG+ G++G+ G+ G  G +GP G  G+ G  GP         DG PG AG
Sbjct: 226 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAG 285

Query: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG--------------- 406
            PG  G  GG G PG PG +G  G  GA+G +G QG  G PG+PG               
Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 345

Query: 407 ------------VKGAKGGPGPRGPKGEPG---------RRGDPGTKGSPGSDGPKGEKG 445
                       + GA G PGPRGP G  G         + G+PG  G  G  GPKGE G
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPG 405

Query: 446 DPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQ---------------GSRG 490
             GP+G  G AGE G +GA+G+ G  GP GP G  G PG +               G RG
Sbjct: 406 PAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG 465

Query: 491 DPGDAGPRGDSGQPGPKGDP---------GRPGFSYP----GPRGAPGEKGEPGPRGPEG 537
             G AGP+G +G PG  G+P         GRPG + P    GP GAPGE G PGP GP+G
Sbjct: 466 PSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQG 525

Query: 538 GRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            RG  G+ G PG KG  GEP   G  G PG  G RG+PG +GE G  G PG
Sbjct: 526 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576



 Score =  308 bits (790), Expect = 1e-83
 Identities = 166/370 (44%), Positives = 196/370 (52%), Gaps = 38/370 (10%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  G  G  G  G +G  G PG+PG  G  G PG  G  G PGP+G  GF G  G  G 
Sbjct: 158 PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGV 217

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            G +G PGL G  G  G  G  G  G PG  G PG  GP G PGE G  G  G  G +G+
Sbjct: 218 KGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277

Query: 375 PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP---GT 431
            G+PG  GPPG +G  G  G+ G  GA G  G  GA+G  G +GP+GEPG  G P   G 
Sbjct: 278 DGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGA 337

Query: 432 KGSPGSD------------------------GPKGEKGDPGPEGPRGLAGE---VGNKGA 464
            G+PG+D                        GP G +G  GP GP+G  GE    G KG 
Sbjct: 338 SGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE 397

Query: 465 KGDRGLPGPRGPQGA---LGEPGKQGSRGDPGDA---GPRGDSGQPGPKGDPGRPGFSYP 518
           +G +G PGP GPQGA    GE GK+G+RG+PG     GP G+ G PG +G PG+ G +  
Sbjct: 398 QGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA-- 455

Query: 519 GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE 578
           GP+GAPGE+G  G  GP+G  GD G  GEPG  G +G    PG  G  G  GP G PG +
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515

Query: 579 GEPGPPGDPG 588
           G PGPPG  G
Sbjct: 516 GRPGPPGPQG 525



 Score =  306 bits (785), Expect = 4e-83
 Identities = 176/370 (47%), Positives = 202/370 (54%), Gaps = 37/370 (10%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPG---QKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           PG  GP G  G KGA G+ G PGEPG    +G  G PG  GP G  GP G PG  G  G 
Sbjct: 461 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 312 FGADGRKGAPGLAG------KNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY---PGEAGS 362
            G  G +G PG+ G       NG  G+ G+ G  G PG +G PG  G  G    PG AG 
Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580

Query: 363 PGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
            GERG+QG  G     G PG  GPPGE G  G +G  G +GAPG  G +G +G PG RG 
Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 420 KGEPGRRGDPGTKGSPGSDGPKGEK---GDPGPEGPRGLAGEVGNKGA------KGDRGL 470
            G  G +G  G  G+PG+DGPKG     G PG +GP GL G  G +GA      KGDRG 
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700

Query: 471 PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGE 529
            G +GP+GA   PGK G RG  G  GP G +G  G KG+ G PG     G RGAPGE+GE
Sbjct: 701 VGEKGPEGA---PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757

Query: 530 PGPRGPEGGRGDFGLKGEPGRKGEKGE---------PADPGPPGEPGPRGPRGVPGPEGE 580
            GP GP G  G  G  G+PG KGE+GE         P   GP G PGP+GP GV GP+G 
Sbjct: 758 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 817

Query: 581 PGPPGDPGLT 590
            G  G PG T
Sbjct: 818 RGAQGPPGAT 827



 Score =  305 bits (780), Expect = 1e-82
 Identities = 175/392 (44%), Positives = 202/392 (51%), Gaps = 59/392 (15%)

Query: 256  GPSGPKGYRGQKGAKGN---MGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            GP GP G+ G  GA G     GE GE GQKG  G PG +GP G PGP+G  G  G KG  
Sbjct: 759  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 313  GADGRKGA---------------------PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR 351
            GA G  GA                     PG  G +G DG KG  G  GPPG  G+PG +
Sbjct: 819  GAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQ 878

Query: 352  GPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAP--------- 402
            GP G PGE G PG+ G  G +G PG  G  G  G +G  G +G +G  G P         
Sbjct: 879  GPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQ 938

Query: 403  GSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G+PG  G +G PGP GP G  G  G+PG +GSPG+DGP G  G  G +G RG  G VG  
Sbjct: 939  GAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998

Query: 463  GAKGDRGLPGPRGP------------QGALGEPGKQGSRGDPGDAGPRGD---SGQPGPK 507
            GA G  G PGP GP            QG +G  G  G+RG  G  GPRGD   +G+PG +
Sbjct: 999  GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1058

Query: 508  GDPGRPGFS----YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP 563
            G  G  GF+     PGP G  G++G  GP GP G RG  G  G  G+ G  G P   GPP
Sbjct: 1059 GLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118

Query: 564  ------GEPGPRGPRGVPGPEGEPGPPGDPGL 589
                  GE GP GP G PGP G PGPPG PG+
Sbjct: 1119 GPRGRSGETGPAGPPGNPGPPGPPGPPG-PGI 1149



 Score =  304 bits (778), Expect = 3e-82
 Identities = 184/429 (42%), Positives = 213/429 (49%), Gaps = 98/429 (22%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQ------------------KGRQGDPGIEGPIGFP 297
           G +GP G RG +GA+G  GEPG PG                   KG  G PGI G  GFP
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365

Query: 298 GPKGVPG---------------------FKGE---KGEFGADGRKGAPGLA---GKNGTD 330
           GP+G PG                     FKGE   KGE G  G +GAPG A   GK G  
Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 331 GQKGKLGRIGPPGCKGDPGNR---------GPDGYPGEAGSPGERGDQGGKGDPGRPGR- 380
           G+ G +G IGPPG +G PGNR         GP G PGE G  G  G +G  GDPGRPG  
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 381 --------------RGPPGEIGAKGSKGYQGNSGAPGSPGVK---GAKGGPGPRGPKGEP 423
                          GP G++G  G+ G  G  G PG  G +   G  G PGP+G  GEP
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545

Query: 424 GRRGD------PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477
           G+ G+      PG +G PG DG  G  G PGP GP G  GE G  G  G +GLPGP GP 
Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 478 GALGEPGKQGSRGD---PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAP------GEKG 528
           G  G+PG QG  G+   PG  GPRG+ G PG +G PG  G    GPRG P      G KG
Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ--GPRGLPGTPGTDGPKG 663

Query: 529 EPGPRGPEGGRGDFGLKGEPGR---------KGEKGEPADPGPPGEPGPRGPRGVPGPEG 579
             GP GP G +G  GL+G PG          KG++G+  + GP G PG  G RG+ GP G
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 723

Query: 580 EPGPPGDPG 588
            PGP G  G
Sbjct: 724 PPGPAGANG 732



 Score =  303 bits (775), Expect = 6e-82
 Identities = 167/359 (46%), Positives = 198/359 (55%), Gaps = 28/359 (7%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG +GP+G  G  GA G  G PG PG +G +G PG+   +GFPGPKG  G  G+ GE G 
Sbjct: 497 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV---MGFPGPKGANGEPGKAGEKGL 553

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY---PGEAGSPGERG---D 368
            G  G  GL GK+G  G  G  G  GP G +G+ G  GP G+   PG  G PGE G   D
Sbjct: 554 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613

Query: 369 QGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP--- 419
           QG  G+ G PG  GP      PGE G+ G++G QG  G PG+PG  G KG  GP GP   
Sbjct: 614 QGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGA 673

Query: 420 KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGA 479
           +G PG +G PG +G+ G  GPKG++GD G +GP G  G+ G +G  G  G PGP G  G 
Sbjct: 674 QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGE 733

Query: 480 LGE---PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGE------ 529
            GE   PG  GS G  G  G RG++G PGP G  G PG    PG +G  GE G+      
Sbjct: 734 KGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGA 793

Query: 530 PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           PGP+GP G  G  G  G  G KG +G    PG  G PG  G  G PG  G PGPPG PG
Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852



 Score =  301 bits (771), Expect = 2e-81
 Identities = 174/389 (44%), Positives = 201/389 (51%), Gaps = 55/389 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP GP G +G +G +G+ GE G PG +GR G+PG  G  G PGP G PG  G  G F A
Sbjct: 53  PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 112

Query: 315 D------------------------GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN 350
                                    G +G PG AG  G  G +G  G  G PG  G  G 
Sbjct: 113 QMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP 172

Query: 351 RGPDGYP------GEAGSPGERGD------QGGKGDPGRP------GRRGPPGEIGAKGS 392
           RGP G P      GEAG PG+ G+      QG +G PG P      G RG PG  GAKG 
Sbjct: 173 RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGE 232

Query: 393 KGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP 452
            G  G  G  GSPG  G+ G  GPRG  GE GR G  G  G+ G+DG  G  G PGP GP
Sbjct: 233 AGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGP 292

Query: 453 RGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ---PGPKGD 509
            G  G  G  GAKG+ G  G RGP+GA G  G+ G+ G PG AG  G+ G    PG KG 
Sbjct: 293 AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 510 PGRPGFS----YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
            G PG +    +PGPRG PG +G  GP GP+G  G+ G+ G  G +G KGEP   GP G 
Sbjct: 353 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 412

Query: 566 PGP------RGPRGVPGPEGEPGPPGDPG 588
           PGP      RG RG PG  G  GPPG+ G
Sbjct: 413 PGPAGEEGKRGARGEPGGVGPIGPPGERG 441



 Score =  296 bits (757), Expect = 7e-80
 Identities = 166/372 (44%), Positives = 195/372 (52%), Gaps = 41/372 (11%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           G  GPKG  G  G +G  G  GE G++G +G+PG  GPIG PG +G PG +G  G+ G  
Sbjct: 396 GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA 455

Query: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375
           G KGAPG  G +G  G KG  G  G PG  G PG RG  G PG+AG  G+ G  G  G+ 
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515

Query: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
           GRPG  GP G  G  G  G+ G  GA G PG  G KG PG  G +G PG+ G+ G  G P
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575

Query: 436 GSDGPKGEKGD------------PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
           G  GP GE+G+            PGP GP G  G+ G++G  G+ G PG  GP+G  G P
Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFP 635

Query: 484 GKQGSRGDPGDAGPRGDSGQP---------GPKGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
           G++GS G  G  GPRG  G P         GP G PG  G   PG +G PGE+G  G  G
Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQG--PPGLQGMPGERGAAGIAG 693

Query: 535 PEGGRGDFGLK------------------GEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576
           P+G RGD G K                  G PG  G  GE  + GPPG  G  G RG PG
Sbjct: 694 PKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPG 753

Query: 577 PEGEPGPPGDPG 588
             GE GPPG  G
Sbjct: 754 ERGETGPPGPAG 765



 Score =  295 bits (756), Expect = 9e-80
 Identities = 166/362 (45%), Positives = 186/362 (51%), Gaps = 41/362 (11%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KG 310
            +PG  G  G  G KG +G++GE G  G  G+ G  G+ GPIG PGP G  G KGE    G
Sbjct: 682  MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPG 741

Query: 311  EFGADGRKGAPG------------LAGKNGTDGQKGKLGRIGPPGCKGD---PGNRGPDG 355
              G+ G +GAPG             AG  G DGQ G  G  G  G KGD   PG +GP G
Sbjct: 742  PAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSG 801

Query: 356  YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPG 415
             PG  G  G  G +G +G  G PG  G PG  G  G  G  GN G PG PG  G  G  G
Sbjct: 802  APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861

Query: 416  PRGPKGEPGRRGDPGT---------KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
             RG  G PGR G+PG          KG PG DGP G +G PGP+G  G  G VG  G +G
Sbjct: 862  ARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRG 921

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGE 526
            +RG PG  GP    GEPGKQG+ G  GD GP      PGP G PG       GP G PG 
Sbjct: 922  ERGFPGLPGPS---GEPGKQGAPGASGDRGP------PGPVGPPG-----LTGPAGEPGR 967

Query: 527  KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
            +G PG  GP G  G  G+KG+ G  G  G P  PGPPG PGP GP G  G  GE G  G 
Sbjct: 968  EGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGP 1027

Query: 587  PG 588
             G
Sbjct: 1028 MG 1029



 Score =  289 bits (740), Expect = 6e-78
 Identities = 177/425 (41%), Positives = 205/425 (48%), Gaps = 91/425 (21%)

Query: 255 PGPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGI------EGPIGFPGPKGV 302
           PGP GP+G RGQ G       KG  GEPG+ G+KG  G PG+      +G  G  GP G 
Sbjct: 518 PGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGP 577

Query: 303 PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPG---NRGPDGYPGE 359
            G  GE+GE GA G  G  GL G  G  G+ GK G  G PG  G PG    RG  G+PGE
Sbjct: 578 AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637

Query: 360 AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
            GSPG +G QG +G PG PG  GP G  G  G  G QG  G  G PG +GA G  GP+G 
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697

Query: 420 KGEPGRRGDPGTKGS------------PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
           +G+ G +G  G  G             PG  G  GEKG+ GP GP G AG  G  G +G+
Sbjct: 698 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757

Query: 468 RGLPGPRG---------PQGALGEPGKQGSRGDPGDAGPRGDSGQPGP------------ 506
            G PGP G           GA GE G+ G +GD G  GP+G SG PGP            
Sbjct: 758 TGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGA 817

Query: 507 ---KGDPGRPGF-------------SYPGPRGAPGEKGEPGPR------GPEGGRGDFGL 544
              +G PG  GF               PGP G PG  G+ GP+      GP G  G+ GL
Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877

Query: 545 KGEPGRKGEKGEPADPGPPGEPGPRGPR---------------------GVPGPEGEPGP 583
           +G  G  GEKGEP D GP G  GP GP+                     G+PGP GEPG 
Sbjct: 878 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937

Query: 584 PGDPG 588
            G PG
Sbjct: 938 QGAPG 942



 Score =  288 bits (737), Expect = 1e-77
 Identities = 178/409 (43%), Positives = 198/409 (48%), Gaps = 70/409 (17%)

Query: 255 PGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           PGP GP+G    RG+ G  G  G  G  GQ G  G PG  GP G PG  G PG KGE G 
Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310

Query: 312 FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
            GA G +GA G  G+ GT G  G  G  G PG  G PG +G  G PG AG+PG  G +G 
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG------------- 418
            G  G  G  GP G+ G  G  G++G  G  G PG  G +G PGP G             
Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430

Query: 419 --PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG------------EVGNKGA 464
             P G PG RG PG +G PG DG  G KG PG  GP GLAG            E G  GA
Sbjct: 431 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490

Query: 465 KGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPG------PKGDPGRPGFS-- 516
           +G  G PG  GPQG +G  G  G  G PG  GP+G  GQPG      PKG  G PG +  
Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 517 -----YPGPRGAPGEKGE------PGPRGPEGGRGDFG---------LKGEPGRKGEKGE 556
                 PG RG PG+ GE      PGP GP G RG+ G         L G PG  GE G+
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 557 PADPGPPGEPG------PRGPRGVPGP------EGEPGPPGDPGLTECD 593
           P D G PGE G      PRG RG PG       +G  GP G PG    D
Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTD 659



 Score =  276 bits (705), Expect = 7e-74
 Identities = 158/362 (43%), Positives = 181/362 (50%), Gaps = 62/362 (17%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGE---PGQKGRQGDPGIEG---PIGFPGPKGVPGFKGE 308
            PGP GP G  G KGA+G  G PG    PG  GR G PG  G   P G PGP G  G KG 
Sbjct: 803  PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---------------- 352
            +G+ G  GR G PGL G  G  G+KG+ G  GP G +G PG +G                
Sbjct: 863  RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 353  --------PDGYPGEAGSPGERGDQGGKG------------DPGR---PGRRGPPGEIGA 389
                    P G PG+ G+PG  GD+G  G            +PGR   PG  GPPG  GA
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982

Query: 390  KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP 449
             G KG +G +GA G+PG  G  G PGP GP G+ G RG+ G +G  G  GP G +G  GP
Sbjct: 983  AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGP 1042

Query: 450  EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509
            +GPRG  GE G  G +G +G  G  G QG  G PG  G +G  G AGP G  G PGP   
Sbjct: 1043 QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP--- 1099

Query: 510  PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR 569
                     GP G  G  G PGP GP G R      G  G  G  G P +PGPPG PGP 
Sbjct: 1100 --------VGPSGKDGANGIPGPIGPPGPR------GRSGETGPAGPPGNPGPPGPPGPP 1145

Query: 570  GP 571
            GP
Sbjct: 1146 GP 1147



 Score =  213 bits (542), Expect = 6e-55
 Identities = 129/285 (45%), Positives = 146/285 (51%), Gaps = 27/285 (9%)

Query: 255  PGPSGPKGYRG------QKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP G  G RG      Q+G +G  G PG  G+ G+QG PG  G  G PGP G PG  G 
Sbjct: 902  PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 961

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
             GE    GR+G+PG  G  G DG  G  G  G  G  G PG  GP G PG AG  G++GD
Sbjct: 962  AGE---PGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGD 1018

Query: 369  QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD 428
               +G+ G  G  GP G  GA+G +G QG  G       KG  G PG RG KG  G  G 
Sbjct: 1019 ---RGEAGAQGPMGPSGPAGARGIQGPQGPRGD------KGEAGEPGERGLKGHRGFTGL 1069

Query: 429  PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
             G  G PG  G +G  G  GP GPRG  G VG  G  G  G+PGP GP      PG +G 
Sbjct: 1070 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGP------PGPRGR 1123

Query: 489  RGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG-APGEKGEPGP 532
             G+ G AGP G+ G PGP G PG PG       G  P EKG P P
Sbjct: 1124 SGETGPAGPPGNPGPPGPPGPPG-PGIDMSAFAGLGPREKG-PDP 1166



 Score =  163 bits (412), Expect = 7e-40
 Identities = 108/285 (37%), Positives = 132/285 (46%), Gaps = 48/285 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGE---------PGQKGRQGDPGIEGPIGFPGPKGVPG 304
            +PGPSG  G +G  GA G+ G PG           G+ GR+G PG +GP G  G  GV G
Sbjct: 928  LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGK---------LGRIGPPGCKGDPGNRGPDG 355
             +GE G  GA G  G PG  G  G  G++G          +G  GP G +G  G +GP G
Sbjct: 988  DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 356  YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG--------- 406
              GEAG PGERG +G +G  G  G  GPPG  G +G+ G  G SG  G PG         
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1107

Query: 407  ---VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD--------PGPEGPRGL 455
               + G  G PGPRG  GE G  G PG  G PG  GP G   D        P  +GP  L
Sbjct: 1108 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1167

Query: 456  --------AGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDP 492
                    AG +    A+ D  L        ++  P  +GSR +P
Sbjct: 1168 QYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSP--EGSRKNP 1210



 Score =  155 bits (391), Expect = 2e-37
 Identities = 94/205 (45%), Positives = 101/205 (49%), Gaps = 24/205 (11%)

Query: 405 PGVKGAKGGPGPR----GPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG 460
           PG KG KG PG      GPKG PG +G  G +G  G  G KGEKG PGP   RG  GE G
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGP---RGRDGEPG 87

Query: 461 NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDP------------GDAGPRGDSGQPGPKG 508
             G  G  G PGP GP G  G    Q + G              G  GP G  G PGP G
Sbjct: 88  TPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAG 147

Query: 509 DPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGP 568
            PG  GF     +G PGE GEPG  GP G RG  G  G+PG  GE G+P   G  G PGP
Sbjct: 148 APGPQGF-----QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202

Query: 569 RGPRGVPGPEGEPGPPGDPGLTECD 593
           +G RG PG  G PG  G  G    D
Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLD 227



 Score =  122 bits (305), Expect = 2e-27
 Identities = 83/242 (34%), Positives = 101/242 (41%), Gaps = 16/242 (6%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            G+  +   +  PG  GP G  G  G  G  G+ GE G +G  G  G  G  G  GP+G  
Sbjct: 987  GDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR 1046

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
            G KGE GE G  G KG  G  G  G           GPPG  GD G  GP      AG  
Sbjct: 1047 GDKGEAGEPGERGLKGHRGFTGLQGLP---------GPPGPSGDQGASGP------AGPS 1091

Query: 364  GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
            G RG  G  G  G+ G  G PG IG  G +G  G +G  G PG  G  G PGP GP  + 
Sbjct: 1092 GPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1151

Query: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
                  G +   G D  +  + D    G R    EV       +  +   R P+G+   P
Sbjct: 1152 SAFAGLGPR-EKGPDPLQYMRADQAAGGLRQHDAEVDATLKSLNNQIESIRSPEGSRKNP 1210

Query: 484  GK 485
             +
Sbjct: 1211 AR 1212



 Score = 94.4 bits (233), Expect = 4e-19
 Identities = 52/124 (41%), Positives = 56/124 (45%), Gaps = 35/124 (28%)

Query: 500 DSGQPGPKGDPGRPG--FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP 557
           D  QPGPKG  G PG      GP+G PG +G  G +GP G RGD G KG PG +G  GEP
Sbjct: 27  DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86

Query: 558 ADPGPPGEPGPRGPRGVP---------------------------------GPEGEPGPP 584
             PG PG PGP GP G P                                 GP G PGP 
Sbjct: 87  GTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA 146

Query: 585 GDPG 588
           G PG
Sbjct: 147 GAPG 150


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  319 bits (818), Expect = 6e-87
 Identities = 176/362 (48%), Positives = 200/362 (55%), Gaps = 28/362 (7%)

Query: 255  PGPSGPKG------------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGP 299
            PGP GP G             RG+ G +G  G PG  G  G QG  G  GPIG    PGP
Sbjct: 942  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 1001

Query: 300  KGVPGFKGEKGEFGADGRKGAPG---LAGKNGTDGQKGKLGRIGPPGCKGDPG---NRGP 353
             G PG +G  G  G +G KG PG   ++GK+G  G +G  G  G PG +G PG     GP
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061

Query: 354  DGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGA 410
             G PG  GSPGERG  G  G    PGRPG +GPPG  G KG+ G +G  G  G  GV+G 
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 411  KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G PGP GP G PG  GD G  G PG  G KG+KG+ GP GP GL G VG  G  G  G 
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE 529
            PGPRG QG  G+ G +G+RG PG  GP G  G PGP G+ G  G   P GP G PG +G 
Sbjct: 1182 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1241

Query: 530  PGPR---GPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
             GP    GP+G  G  G  G  G KGE GE  +PGPPGE G  GP+G  G +GE GPPG 
Sbjct: 1242 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301

Query: 587  PG 588
             G
Sbjct: 1302 AG 1303



 Score =  318 bits (816), Expect = 1e-86
 Identities = 177/381 (46%), Positives = 215/381 (56%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGF---------PG 298
            +PGP+GP G  G+ G KG +GEPG+ G KG +G+      PG++GP+G          PG
Sbjct: 1124 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183

Query: 299  PKGVPGFKGEKGEFGADGRKGAP------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352
            P+G  G  G+KG+ GA G  G P      GL G  G  G+ G +G +GPPG  G  G +G
Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1243

Query: 353  PDGYPGEAGSPGERGDQGG---KGDPGRPGRRGPPGEIGA---KGSKGYQGNSGAPGSPG 406
            P+G  G  G PG  G  GG   KG+PG  G  GPPGE G    KG +G +G +G PG+ G
Sbjct: 1244 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1303

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP---------KGEKGDPGPEGPRGLAG 457
              GAKG PG  GPKG PG  G PG  G PG  GP         KGE GDPG  GP G +G
Sbjct: 1304 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1363

Query: 458  EVGNKGAKGDRGLPGP------RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG 511
            E G  G  G RG PG       +G +GA GE G +G  G  G  GP+G +G+PGP+G  G
Sbjct: 1364 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1423

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GLKG+PG KGEKG P      GPPGE G 
Sbjct: 1424 IPG--PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1481

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PG +G PG  GD G+
Sbjct: 1482 KGDRGLPGTQGSPGAKGDGGI 1502



 Score =  315 bits (807), Expect = 1e-85
 Identities = 172/361 (47%), Positives = 200/361 (55%), Gaps = 28/361 (7%)

Query: 256  GPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
            GP+GP+G RG +G       KG  G  G PG  G +G  G +GP+GFPGPKG PG  G+ 
Sbjct: 895  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---PDGYPGEAGSPGER 366
            G  G  G++G  G  GK G  G  G +G  GP G  G  G RG   P G PGE G PG  
Sbjct: 955  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1014

Query: 367  GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
            G +G KGDPG  G  G  G  G +G  G +G  GA G+PG+KG +G  GP GP G PG R
Sbjct: 1015 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074

Query: 427  GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGE------VGNKGAKGDRGLPGPRGPQGA- 479
            G  GT G  G  G  G +G PGP G +G  GE       G  G +G  GLPGP GP G+ 
Sbjct: 1075 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1134

Query: 480  --------LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG-RPGFSYPGPRGAP---GEK 527
                    +GEPG++GS+GD G+ GP G  G  GP G PG   G   PGPRG     G+K
Sbjct: 1135 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1194

Query: 528  GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            G+ G RG  G  G  GL+G PG  GEKGE  D GP G PGP GPRG  GP G  GP G P
Sbjct: 1195 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1254

Query: 588  G 588
            G
Sbjct: 1255 G 1255



 Score =  303 bits (776), Expect = 4e-82
 Identities = 172/371 (46%), Positives = 204/371 (54%), Gaps = 37/371 (9%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG---VPGFKGEKGEF 312
            G  GP+G +G+ G  G+ G  G+ G+KG+ G PG+ G  G  GPKG    PGF G  GE 
Sbjct: 820  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGP---PGCKGDPGNRGPDGYPGEAGSPGERGD- 368
            GA G  G PG  G+ G  G +G  G  GP   PG KG  G  GP G PGE G  G +G  
Sbjct: 880  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 939

Query: 369  --QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE---P 423
               G KG PG PG+ G PG  G +G  G+QG +G PG  GV G +G  G  GP GE   P
Sbjct: 940  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 999

Query: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
            G  G PG +G PG+ G +G KGDPGP+G  G  G  G +G  G+RGLPG +G  G  G  
Sbjct: 1000 GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1059

Query: 484  GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------- 529
            G QG  G  G  G RG +G  GP G PGRPG   P    G +GAPGEKG           
Sbjct: 1060 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1119

Query: 530  -----PGPRGPEGGRGDFGLK---GEPGRKGEKGEPADPGPPGEPGPRGPRGVP---GPE 578
                 PGP GP G  G+ G K   GEPG+KG KG+  + GPPG PG +GP G P   G +
Sbjct: 1120 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1179

Query: 579  GEPGPPGDPGL 589
            GEPGP G  G+
Sbjct: 1180 GEPGPRGQQGM 1190



 Score =  302 bits (773), Expect = 1e-81
 Identities = 160/348 (45%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            + G  GP G +G+ G  G MG PG PG +G QG  G +GP G PG  G  G  GEKGE G
Sbjct: 1211 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1270

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G  G PG AG  G  G++G+ G  GPPG  G PG +GP   PG+ G  G  G  G  G
Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGFPG 1327

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            DPG PG  GP G+ G  G KG  G+ G PG PG  G  G PGP G +G PG  G  G +G
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1387

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G+ G  G +G PG  GP G  G  G  G +G RG+PGP G QG  G  G+ G  G  G
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G  G PG KG+ G PG    G  G PGE+GE G RG  G +G  G KG+ G  G 
Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLI--GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1505

Query: 554  KGEPADPGPPGEPGPRGPR---------------GVPGPEGEPGPPGD 586
             G    PGPPG PGP+GP+               G+PGP G PGPPG+
Sbjct: 1506 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553



 Score =  300 bits (769), Expect = 3e-81
 Identities = 168/365 (46%), Positives = 196/365 (53%), Gaps = 37/365 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP GP G +G  GA G  G  G+PG +G  G  G  G  GFPG +G+PG +G  G  G 
Sbjct: 999  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG- 373
            +G +G PG  G   + G++G  G  GP G  G PG +GP G  GE G+PGE+G QG  G 
Sbjct: 1059 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1115

Query: 374  -----------------DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
                              PG  G +G  GE G KGSKG +G +G PG PG++G  G PG 
Sbjct: 1116 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1175

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP---RGLAGEVGNKGAKGD------ 467
             G  GEPG RG  G  G  G +G +G    PGP GP   +GL G  G KG  GD      
Sbjct: 1176 AGGDGEPGPRGQQGMFGQKGDEGARGF---PGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232

Query: 468  RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGE 526
             G PGPRGPQG  G  G QG  G  G  G  G+ G+PG  G+PG PG     GP+G  GE
Sbjct: 1233 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1292

Query: 527  KGE---PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            KGE   PG  GP G +G  G  G  G  G  G P DPGPPGEPGP G  GV G +GE G 
Sbjct: 1293 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1352

Query: 584  PGDPG 588
            PG PG
Sbjct: 1353 PGQPG 1357



 Score =  300 bits (768), Expect = 4e-81
 Identities = 164/368 (44%), Positives = 196/368 (53%), Gaps = 22/368 (5%)

Query: 244  GECYKVSCLEIPGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
            G+  +   L  PGP GP GY   RG KGA G  G  G  G+KG  G PG +G +G  G +
Sbjct: 751  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 810

Query: 301  GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
            G  G  G +GE G +G KG  G  G  G  GQ G+ G++G PG  G PG +GP G  G  
Sbjct: 811  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870

Query: 361  GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGS------------KGYQGNSGAPGSPGVK 408
            G PG  G++G +G  G+PG RG  G  G +GS            KG  G  G PG PG +
Sbjct: 871  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 930

Query: 409  GAKGG------PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G +G       PGP+GP G PG+ G PG  G  G  G +G+ G PGP G  G  G  G  
Sbjct: 931  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 990

Query: 463  GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPR 521
            G  G+RG PGP GP G  G PG  G  G  GD GP+G SG+ GP G  G PG    PG +
Sbjct: 991  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1050

Query: 522  GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEP 581
            GAPG KG  GP+GP G  G  G +G  G  G  G P  PGP G PGP G +G PG +G  
Sbjct: 1051 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1110

Query: 582  GPPGDPGL 589
            GP G  G+
Sbjct: 1111 GPAGRDGV 1118



 Score =  298 bits (763), Expect = 1e-80
 Identities = 170/378 (44%), Positives = 195/378 (51%), Gaps = 46/378 (12%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI------------EGPIGFPGPKGV 302
           PGP+G  G RG+ GA G  G PGEPG KG +G  G+             GP G PGP G 
Sbjct: 582 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 641

Query: 303 PGFKGEKGEF------------------GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGC 344
            G +GE GE                   G  G  G PG+AG +G  G KG +G  G PG 
Sbjct: 642 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 701

Query: 345 KGDPGNRGPDGYP---GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGA 401
            G  GN GP G P   G  G PGE+G QG  G  G PG  GPPG     G +G  G  GA
Sbjct: 702 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH---PGKEGQSGEKGA 758

Query: 402 PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN 461
            G PG +G  G PGPRG KG  G RG  G+KG  G DG  G KGD G +G RG  G++G 
Sbjct: 759 LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP 818

Query: 462 KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF------ 515
           +G  G  G  G  GP G  G  G+ G +G  G  G  G  G+ GPKG  G PGF      
Sbjct: 819 RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 878

Query: 516 -SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR-- 572
               G  G PG +G+ GP GP G RG  G  G+PG KG  G    PGPPGE GP+GP+  
Sbjct: 879 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 938

Query: 573 -GVPGPEGEPGPPGDPGL 589
            G PGP+G PGPPG  GL
Sbjct: 939 VGFPGPKGPPGPPGKDGL 956



 Score =  293 bits (749), Expect = 6e-79
 Identities = 165/362 (45%), Positives = 192/362 (53%), Gaps = 44/362 (12%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV---PGFKGEKGE 311
            PGP GP G  G+KGA      PGE G +G  G  G++GP+G PGP G    PG  G+KGE
Sbjct: 1089 PGPQGPPGPAGEKGA------PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1142

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G  G+KG+ G  G+NG  G  G  G +G PG  G  G  GP G   + G  G++GD+G 
Sbjct: 1143 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG---QQGMFGQKGDEGA 1199

Query: 372  KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
            +G PG      PPG IG +G  G  G  G  G  G  G  G PGPRGP+G  G  G  G 
Sbjct: 1200 RGFPG------PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1253

Query: 432  KGSPGSDGPKGEKGD------PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK 485
             GS GS G  GEKG+      PGP G  G+ G  G +G KG+ G PG  GP GA G PG 
Sbjct: 1254 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1313

Query: 486  QGSRGDPGDAGPRGDSGQP---------------GPKGDPGRPGFSYPGPRGAPGEKGEP 530
             G +G+PG  G  GD G P               G  GDPG+PG   PGP G  G  G P
Sbjct: 1314 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPP 1371

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE---GEPGPPGDP 587
            G RGP G  G  G +GE G KGE G    PG  G  GP+GP G PGPE   G PGP G+ 
Sbjct: 1372 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1431

Query: 588  GL 589
            GL
Sbjct: 1432 GL 1433



 Score =  291 bits (746), Expect = 1e-78
 Identities = 163/366 (44%), Positives = 190/366 (51%), Gaps = 31/366 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG---------PKGVPG 304
            I G  GP G RG  G +G  G  G PG KG +G  G  GP+G PG         P G+PG
Sbjct: 1028 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
              G +G  G  G KGAPG  G  G  G+ G  G +G PG  G  G+ G DG  GE G PG
Sbjct: 1088 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1147

Query: 365  ERGDQGGKGDPGRPG------------------RRGPPGEIGAKGSKGYQGNSGAPGSPG 406
            ++G +G KG+ G PG                    GP G+ G  G KG +G  G PG PG
Sbjct: 1148 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1207

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G +G PGP G KGE G  G  G  G PG  GP+G  G  GP+GP G  G VG  G KG
Sbjct: 1208 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1267

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPG 525
            + G  G  GP G  G  G +G RG+ G+AGP G +G PG KG PG  G    PGP G PG
Sbjct: 1268 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1327

Query: 526  E---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
            +    GEPGP G +G  GD G  G+PG+ G  G   + GPPG PG RGP G  G EG  G
Sbjct: 1328 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1387

Query: 583  PPGDPG 588
              G  G
Sbjct: 1388 EKGAKG 1393



 Score =  291 bits (744), Expect = 2e-78
 Identities = 169/359 (47%), Positives = 190/359 (52%), Gaps = 28/359 (7%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG------PIGFPGPKGVPGFKGE 308
            PG  G  G  G  G KGNMG  GEPG  G+QG+PG +G      PIG PG KG  G  G 
Sbjct: 675  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 734

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR------------GPDGY 356
             G  GAD   G PG  GK G  G+KG LG  GP G  G PG R            G  G 
Sbjct: 735  AGLPGAD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791

Query: 357  PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
             GE G PG +GD G KGD G  G+ GP GE G +G KG  G +G PG  G  G KG  G 
Sbjct: 792  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 851

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEK------GDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G  G PGR+G  G+ G PG  G  GEK      G PGP G RG  G  G++GA+G  G 
Sbjct: 852  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 911

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGE 529
            PGP+G  G  G PG  G RG  G  GP G  G  GP G PG+ G   +PG RG  G +G+
Sbjct: 912  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 971

Query: 530  PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP G  G
Sbjct: 972  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1030



 Score =  280 bits (716), Expect = 4e-75
 Identities = 172/448 (38%), Positives = 218/448 (48%), Gaps = 75/448 (16%)

Query: 206 STPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEI----------P 255
           S P+E    ++   +P  T+I + +IN       H AYGE  +     +          P
Sbjct: 407 SPPNE----EFGPGVPAETDITETSING------HGAYGEKGQKGEPAVVEPGMLVEGPP 456

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----------PGF 305
           GP+GP G  G  G +G  G PG+PG +G  G PG+ G  G PGP G            G 
Sbjct: 457 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 516

Query: 306 KGE--------------------KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCK 345
           KG                     +G  G  G  G PG  G  G+ G KG+ G  GP G +
Sbjct: 517 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 576

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRR------GPPGEIGAKGSKGYQGNS 399
           G  G  GP G PG+ G PG  G +G  G+PG  G R      G PG+ G +G +G QG  
Sbjct: 577 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 636

Query: 400 GAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEV 459
           G PG  G++G  G  GPRG  GE G RG  G +G+PG+ G  G  G  GP GP+G  G  
Sbjct: 637 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696

Query: 460 GNKGAKGDRGLPGPR---GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-- 514
           G  G  G +G PGP+   GPQG +G PG++G +G PG AG  G  G PG  G  G+ G  
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 756

Query: 515 -----------FSYPGPRGAPGEKGEPGPRGPEGGRGDF---GLKGEPGRKGEKGEPADP 560
                        YPGPRG  G  G  G +G +G +G+    G KG+ G KG++GE    
Sbjct: 757 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816

Query: 561 GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           GP GE GP GP+G  GP G+PGP G  G
Sbjct: 817 GPRGEDGPEGPKGRAGPTGDPGPSGQAG 844



 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/331 (44%), Positives = 170/331 (51%), Gaps = 32/331 (9%)

Query: 274 GEPGEPGQKGRQG--DPG--IEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329
           G  GE GQKG     +PG  +EGP   PGP G  G  G  G  G  G  G PG  G  G 
Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGP---PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR 488

Query: 330 DGQKGKLGRIGPPGCKGD-PGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIG 388
            G  G  G  GPPG     P   G DG  G   S  E   Q       R   RGPPG +G
Sbjct: 489 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRGPPGPMG 547

Query: 389 AKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG---EPGRRGDPGTKGSPGSDGPKGEKG 445
             G  G     G PGS G KG  G PGP+GP+G    PG  G PG +G PG+DG +G  G
Sbjct: 548 LTGRPG---PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604

Query: 446 DPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPG 505
           +PG +G RG  G  G  G KG RG    RGPQG  G PG  G RG+ G+ GPRG  G+ G
Sbjct: 605 EPGAKGDRGFDGLPGLPGDKGHRG---ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 661

Query: 506 PKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEPADPGP 562
           P+G          GPRG PG  G+PG  G   P G +G+ G +GEPG  G++G   +PGP
Sbjct: 662 PRG--------LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG---NPGP 710

Query: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            G PGP+GP G PG +G  G PG  GL   D
Sbjct: 711 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741



 Score =  177 bits (448), Expect = 5e-44
 Identities = 92/195 (47%), Positives = 112/195 (57%), Gaps = 3/195 (1%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G +G  G  GA+G  GE G  G+ G +G PG  GP+G  GP G PG +G +G  G 
Sbjct: 1368 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1427

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G +G PG AG+   DG  G +G  G PG KGDPG++G  G+PG  G  G  G+QG KGD
Sbjct: 1428 VGEQGLPGAAGQ---DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD 1484

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G PG +G PG  G  G  G  G  G PG PG+ G +G  G +G  G  G++GD G  G 
Sbjct: 1485 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544

Query: 435  PGSDGPKGEKGDPGP 449
            PGS GP GE   P P
Sbjct: 1545 PGSPGPPGEVIQPLP 1559



 Score =  112 bits (279), Expect = 2e-24
 Identities = 66/143 (46%), Positives = 78/143 (54%), Gaps = 21/143 (14%)

Query: 254  IPGPSGPKGY---RGQKGAKGNMGEPG------EPGQKGRQGDPGIEGPIGFPGPKGVPG 304
            IPGP G +G     GQ G  G MG PG      +PG KG +G PG+   IG  GP   PG
Sbjct: 1424 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL---IGLIGP---PG 1477

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
             +GEKG+ G  G +G+PG  G  G  G  G LG  GPPG    PG +GP G  G  G  G
Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAG 1534

Query: 365  ERGDQGGKGDPGRPGRRGPPGEI 387
            ++GD G  G PG P   GPPGE+
Sbjct: 1535 QKGDSGLPGPPGSP---GPPGEV 1554


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  319 bits (818), Expect = 6e-87
 Identities = 176/362 (48%), Positives = 200/362 (55%), Gaps = 28/362 (7%)

Query: 255  PGPSGPKG------------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGP 299
            PGP GP G             RG+ G +G  G PG  G  G QG  G  GPIG    PGP
Sbjct: 891  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 950

Query: 300  KGVPGFKGEKGEFGADGRKGAPG---LAGKNGTDGQKGKLGRIGPPGCKGDPG---NRGP 353
             G PG +G  G  G +G KG PG   ++GK+G  G +G  G  G PG +G PG     GP
Sbjct: 951  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010

Query: 354  DGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGA 410
             G PG  GSPGERG  G  G    PGRPG +GPPG  G KG+ G +G  G  G  GV+G 
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 411  KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G PGP GP G PG  GD G  G PG  G KG+KG+ GP GP GL G VG  G  G  G 
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE 529
            PGPRG QG  G+ G +G+RG PG  GP G  G PGP G+ G  G   P GP G PG +G 
Sbjct: 1131 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1190

Query: 530  PGPR---GPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
             GP    GP+G  G  G  G  G KGE GE  +PGPPGE G  GP+G  G +GE GPPG 
Sbjct: 1191 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250

Query: 587  PG 588
             G
Sbjct: 1251 AG 1252



 Score =  318 bits (816), Expect = 1e-86
 Identities = 177/381 (46%), Positives = 215/381 (56%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGF---------PG 298
            +PGP+GP G  G+ G KG +GEPG+ G KG +G+      PG++GP+G          PG
Sbjct: 1073 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1132

Query: 299  PKGVPGFKGEKGEFGADGRKGAP------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352
            P+G  G  G+KG+ GA G  G P      GL G  G  G+ G +G +GPPG  G  G +G
Sbjct: 1133 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1192

Query: 353  PDGYPGEAGSPGERGDQGG---KGDPGRPGRRGPPGEIGA---KGSKGYQGNSGAPGSPG 406
            P+G  G  G PG  G  GG   KG+PG  G  GPPGE G    KG +G +G +G PG+ G
Sbjct: 1193 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1252

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP---------KGEKGDPGPEGPRGLAG 457
              GAKG PG  GPKG PG  G PG  G PG  GP         KGE GDPG  GP G +G
Sbjct: 1253 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1312

Query: 458  EVGNKGAKGDRGLPGP------RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG 511
            E G  G  G RG PG       +G +GA GE G +G  G  G  GP+G +G+PGP+G  G
Sbjct: 1313 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1372

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GLKG+PG KGEKG P      GPPGE G 
Sbjct: 1373 IPG--PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1430

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PG +G PG  GD G+
Sbjct: 1431 KGDRGLPGTQGSPGAKGDGGI 1451



 Score =  315 bits (807), Expect = 1e-85
 Identities = 172/361 (47%), Positives = 200/361 (55%), Gaps = 28/361 (7%)

Query: 256  GPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
            GP+GP+G RG +G       KG  G  G PG  G +G  G +GP+GFPGPKG PG  G+ 
Sbjct: 844  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---PDGYPGEAGSPGER 366
            G  G  G++G  G  GK G  G  G +G  GP G  G  G RG   P G PGE G PG  
Sbjct: 904  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 963

Query: 367  GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
            G +G KGDPG  G  G  G  G +G  G +G  GA G+PG+KG +G  GP GP G PG R
Sbjct: 964  GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023

Query: 427  GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGE------VGNKGAKGDRGLPGPRGPQGA- 479
            G  GT G  G  G  G +G PGP G +G  GE       G  G +G  GLPGP GP G+ 
Sbjct: 1024 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1083

Query: 480  --------LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG-RPGFSYPGPRGAP---GEK 527
                    +GEPG++GS+GD G+ GP G  G  GP G PG   G   PGPRG     G+K
Sbjct: 1084 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1143

Query: 528  GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            G+ G RG  G  G  GL+G PG  GEKGE  D GP G PGP GPRG  GP G  GP G P
Sbjct: 1144 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1203

Query: 588  G 588
            G
Sbjct: 1204 G 1204



 Score =  303 bits (776), Expect = 4e-82
 Identities = 172/371 (46%), Positives = 204/371 (54%), Gaps = 37/371 (9%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG---VPGFKGEKGEF 312
            G  GP+G +G+ G  G+ G  G+ G+KG+ G PG+ G  G  GPKG    PGF G  GE 
Sbjct: 769  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGP---PGCKGDPGNRGPDGYPGEAGSPGERGD- 368
            GA G  G PG  G+ G  G +G  G  GP   PG KG  G  GP G PGE G  G +G  
Sbjct: 829  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 888

Query: 369  --QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE---P 423
               G KG PG PG+ G PG  G +G  G+QG +G PG  GV G +G  G  GP GE   P
Sbjct: 889  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 948

Query: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
            G  G PG +G PG+ G +G KGDPGP+G  G  G  G +G  G+RGLPG +G  G  G  
Sbjct: 949  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1008

Query: 484  GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------- 529
            G QG  G  G  G RG +G  GP G PGRPG   P    G +GAPGEKG           
Sbjct: 1009 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1068

Query: 530  -----PGPRGPEGGRGDFGLK---GEPGRKGEKGEPADPGPPGEPGPRGPRGVP---GPE 578
                 PGP GP G  G+ G K   GEPG+KG KG+  + GPPG PG +GP G P   G +
Sbjct: 1069 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1128

Query: 579  GEPGPPGDPGL 589
            GEPGP G  G+
Sbjct: 1129 GEPGPRGQQGM 1139



 Score =  302 bits (773), Expect = 1e-81
 Identities = 160/348 (45%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            + G  GP G +G+ G  G MG PG PG +G QG  G +GP G PG  G  G  GEKGE G
Sbjct: 1160 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1219

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G  G PG AG  G  G++G+ G  GPPG  G PG +GP   PG+ G  G  G  G  G
Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGFPG 1276

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            DPG PG  GP G+ G  G KG  G+ G PG PG  G  G PGP G +G PG  G  G +G
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1336

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G+ G  G +G PG  GP G  G  G  G +G RG+PGP G QG  G  G+ G  G  G
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G  G PG KG+ G PG    G  G PGE+GE G RG  G +G  G KG+ G  G 
Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLI--GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1454

Query: 554  KGEPADPGPPGEPGPRGPR---------------GVPGPEGEPGPPGD 586
             G    PGPPG PGP+GP+               G+PGP G PGPPG+
Sbjct: 1455 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502



 Score =  300 bits (769), Expect = 3e-81
 Identities = 168/365 (46%), Positives = 196/365 (53%), Gaps = 37/365 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP GP G +G  GA G  G  G+PG +G  G  G  G  GFPG +G+PG +G  G  G 
Sbjct: 948  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG- 373
            +G +G PG  G   + G++G  G  GP G  G PG +GP G  GE G+PGE+G QG  G 
Sbjct: 1008 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1064

Query: 374  -----------------DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
                              PG  G +G  GE G KGSKG +G +G PG PG++G  G PG 
Sbjct: 1065 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1124

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP---RGLAGEVGNKGAKGD------ 467
             G  GEPG RG  G  G  G +G +G    PGP GP   +GL G  G KG  GD      
Sbjct: 1125 AGGDGEPGPRGQQGMFGQKGDEGARGF---PGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181

Query: 468  RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGE 526
             G PGPRGPQG  G  G QG  G  G  G  G+ G+PG  G+PG PG     GP+G  GE
Sbjct: 1182 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1241

Query: 527  KGE---PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            KGE   PG  GP G +G  G  G  G  G  G P DPGPPGEPGP G  GV G +GE G 
Sbjct: 1242 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1301

Query: 584  PGDPG 588
            PG PG
Sbjct: 1302 PGQPG 1306



 Score =  300 bits (768), Expect = 4e-81
 Identities = 164/368 (44%), Positives = 196/368 (53%), Gaps = 22/368 (5%)

Query: 244  GECYKVSCLEIPGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
            G+  +   L  PGP GP GY   RG KGA G  G  G  G+KG  G PG +G +G  G +
Sbjct: 700  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 759

Query: 301  GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
            G  G  G +GE G +G KG  G  G  G  GQ G+ G++G PG  G PG +GP G  G  
Sbjct: 760  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819

Query: 361  GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGS------------KGYQGNSGAPGSPGVK 408
            G PG  G++G +G  G+PG RG  G  G +GS            KG  G  G PG PG +
Sbjct: 820  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 879

Query: 409  GAKGG------PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G +G       PGP+GP G PG+ G PG  G  G  G +G+ G PGP G  G  G  G  
Sbjct: 880  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 939

Query: 463  GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPR 521
            G  G+RG PGP GP G  G PG  G  G  GD GP+G SG+ GP G  G PG    PG +
Sbjct: 940  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 999

Query: 522  GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEP 581
            GAPG KG  GP+GP G  G  G +G  G  G  G P  PGP G PGP G +G PG +G  
Sbjct: 1000 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1059

Query: 582  GPPGDPGL 589
            GP G  G+
Sbjct: 1060 GPAGRDGV 1067



 Score =  298 bits (763), Expect = 1e-80
 Identities = 170/378 (44%), Positives = 195/378 (51%), Gaps = 46/378 (12%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI------------EGPIGFPGPKGV 302
           PGP+G  G RG+ GA G  G PGEPG KG +G  G+             GP G PGP G 
Sbjct: 531 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 590

Query: 303 PGFKGEKGEF------------------GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGC 344
            G +GE GE                   G  G  G PG+AG +G  G KG +G  G PG 
Sbjct: 591 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 650

Query: 345 KGDPGNRGPDGYP---GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGA 401
            G  GN GP G P   G  G PGE+G QG  G  G PG  GPPG     G +G  G  GA
Sbjct: 651 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH---PGKEGQSGEKGA 707

Query: 402 PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN 461
            G PG +G  G PGPRG KG  G RG  G+KG  G DG  G KGD G +G RG  G++G 
Sbjct: 708 LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP 767

Query: 462 KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF------ 515
           +G  G  G  G  GP G  G  G+ G +G  G  G  G  G+ GPKG  G PGF      
Sbjct: 768 RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 827

Query: 516 -SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR-- 572
               G  G PG +G+ GP GP G RG  G  G+PG KG  G    PGPPGE GP+GP+  
Sbjct: 828 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887

Query: 573 -GVPGPEGEPGPPGDPGL 589
            G PGP+G PGPPG  GL
Sbjct: 888 VGFPGPKGPPGPPGKDGL 905



 Score =  293 bits (749), Expect = 6e-79
 Identities = 165/362 (45%), Positives = 192/362 (53%), Gaps = 44/362 (12%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV---PGFKGEKGE 311
            PGP GP G  G+KGA      PGE G +G  G  G++GP+G PGP G    PG  G+KGE
Sbjct: 1038 PGPQGPPGPAGEKGA------PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1091

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G  G+KG+ G  G+NG  G  G  G +G PG  G  G  GP G   + G  G++GD+G 
Sbjct: 1092 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG---QQGMFGQKGDEGA 1148

Query: 372  KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
            +G PG      PPG IG +G  G  G  G  G  G  G  G PGPRGP+G  G  G  G 
Sbjct: 1149 RGFPG------PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1202

Query: 432  KGSPGSDGPKGEKGD------PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK 485
             GS GS G  GEKG+      PGP G  G+ G  G +G KG+ G PG  GP GA G PG 
Sbjct: 1203 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1262

Query: 486  QGSRGDPGDAGPRGDSGQP---------------GPKGDPGRPGFSYPGPRGAPGEKGEP 530
             G +G+PG  G  GD G P               G  GDPG+PG   PGP G  G  G P
Sbjct: 1263 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPP 1320

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE---GEPGPPGDP 587
            G RGP G  G  G +GE G KGE G    PG  G  GP+GP G PGPE   G PGP G+ 
Sbjct: 1321 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1380

Query: 588  GL 589
            GL
Sbjct: 1381 GL 1382



 Score =  291 bits (746), Expect = 1e-78
 Identities = 163/366 (44%), Positives = 190/366 (51%), Gaps = 31/366 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG---------PKGVPG 304
            I G  GP G RG  G +G  G  G PG KG +G  G  GP+G PG         P G+PG
Sbjct: 977  ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
              G +G  G  G KGAPG  G  G  G+ G  G +G PG  G  G+ G DG  GE G PG
Sbjct: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1096

Query: 365  ERGDQGGKGDPGRPG------------------RRGPPGEIGAKGSKGYQGNSGAPGSPG 406
            ++G +G KG+ G PG                    GP G+ G  G KG +G  G PG PG
Sbjct: 1097 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1156

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G +G PGP G KGE G  G  G  G PG  GP+G  G  GP+GP G  G VG  G KG
Sbjct: 1157 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1216

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPG 525
            + G  G  GP G  G  G +G RG+ G+AGP G +G PG KG PG  G    PGP G PG
Sbjct: 1217 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1276

Query: 526  E---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
            +    GEPGP G +G  GD G  G+PG+ G  G   + GPPG PG RGP G  G EG  G
Sbjct: 1277 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1336

Query: 583  PPGDPG 588
              G  G
Sbjct: 1337 EKGAKG 1342



 Score =  291 bits (744), Expect = 2e-78
 Identities = 169/359 (47%), Positives = 190/359 (52%), Gaps = 28/359 (7%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG------PIGFPGPKGVPGFKGE 308
           PG  G  G  G  G KGNMG  GEPG  G+QG+PG +G      PIG PG KG  G  G 
Sbjct: 624 PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 683

Query: 309 KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR------------GPDGY 356
            G  GAD   G PG  GK G  G+KG LG  GP G  G PG R            G  G 
Sbjct: 684 AGLPGAD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740

Query: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
            GE G PG +GD G KGD G  G+ GP GE G +G KG  G +G PG  G  G KG  G 
Sbjct: 741 KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 800

Query: 417 RGPKGEPGRRGDPGTKGSPGSDGPKGEK------GDPGPEGPRGLAGEVGNKGAKGDRGL 470
            G  G PGR+G  G+ G PG  G  GEK      G PGP G RG  G  G++GA+G  G 
Sbjct: 801 PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 860

Query: 471 PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGE 529
           PGP+G  G  G PG  G RG  G  GP G  G  GP G PG+ G   +PG RG  G +G+
Sbjct: 861 PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 920

Query: 530 PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP G  G
Sbjct: 921 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 979



 Score =  280 bits (716), Expect = 4e-75
 Identities = 172/448 (38%), Positives = 218/448 (48%), Gaps = 75/448 (16%)

Query: 206 STPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEI----------P 255
           S P+E    ++   +P  T+I + +IN       H AYGE  +     +          P
Sbjct: 356 SPPNE----EFGPGVPAETDITETSING------HGAYGEKGQKGEPAVVEPGMLVEGPP 405

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----------PGF 305
           GP+GP G  G  G +G  G PG+PG +G  G PG+ G  G PGP G            G 
Sbjct: 406 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 465

Query: 306 KGE--------------------KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCK 345
           KG                     +G  G  G  G PG  G  G+ G KG+ G  GP G +
Sbjct: 466 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 525

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRR------GPPGEIGAKGSKGYQGNS 399
           G  G  GP G PG+ G PG  G +G  G+PG  G R      G PG+ G +G +G QG  
Sbjct: 526 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 585

Query: 400 GAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEV 459
           G PG  G++G  G  GPRG  GE G RG  G +G+PG+ G  G  G  GP GP+G  G  
Sbjct: 586 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645

Query: 460 GNKGAKGDRGLPGPR---GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-- 514
           G  G  G +G PGP+   GPQG +G PG++G +G PG AG  G  G PG  G  G+ G  
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705

Query: 515 -----------FSYPGPRGAPGEKGEPGPRGPEGGRGDF---GLKGEPGRKGEKGEPADP 560
                        YPGPRG  G  G  G +G +G +G+    G KG+ G KG++GE    
Sbjct: 706 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765

Query: 561 GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           GP GE GP GP+G  GP G+PGP G  G
Sbjct: 766 GPRGEDGPEGPKGRAGPTGDPGPSGQAG 793



 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/331 (44%), Positives = 170/331 (51%), Gaps = 32/331 (9%)

Query: 274 GEPGEPGQKGRQG--DPG--IEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329
           G  GE GQKG     +PG  +EGP   PGP G  G  G  G  G  G  G PG  G  G 
Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGP---PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR 437

Query: 330 DGQKGKLGRIGPPGCKGD-PGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIG 388
            G  G  G  GPPG     P   G DG  G   S  E   Q       R   RGPPG +G
Sbjct: 438 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRGPPGPMG 496

Query: 389 AKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG---EPGRRGDPGTKGSPGSDGPKGEKG 445
             G  G     G PGS G KG  G PGP+GP+G    PG  G PG +G PG+DG +G  G
Sbjct: 497 LTGRPG---PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553

Query: 446 DPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPG 505
           +PG +G RG  G  G  G KG RG    RGPQG  G PG  G RG+ G+ GPRG  G+ G
Sbjct: 554 EPGAKGDRGFDGLPGLPGDKGHRG---ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 610

Query: 506 PKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEPADPGP 562
           P+G          GPRG PG  G+PG  G   P G +G+ G +GEPG  G++G   +PGP
Sbjct: 611 PRG--------LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG---NPGP 659

Query: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            G PGP+GP G PG +G  G PG  GL   D
Sbjct: 660 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690



 Score =  177 bits (448), Expect = 5e-44
 Identities = 92/195 (47%), Positives = 112/195 (57%), Gaps = 3/195 (1%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G +G  G  GA+G  GE G  G+ G +G PG  GP+G  GP G PG +G +G  G 
Sbjct: 1317 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1376

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G +G PG AG+   DG  G +G  G PG KGDPG++G  G+PG  G  G  G+QG KGD
Sbjct: 1377 VGEQGLPGAAGQ---DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD 1433

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G PG +G PG  G  G  G  G  G PG PG+ G +G  G +G  G  G++GD G  G 
Sbjct: 1434 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493

Query: 435  PGSDGPKGEKGDPGP 449
            PGS GP GE   P P
Sbjct: 1494 PGSPGPPGEVIQPLP 1508



 Score =  112 bits (279), Expect = 2e-24
 Identities = 66/143 (46%), Positives = 78/143 (54%), Gaps = 21/143 (14%)

Query: 254  IPGPSGPKGY---RGQKGAKGNMGEPG------EPGQKGRQGDPGIEGPIGFPGPKGVPG 304
            IPGP G +G     GQ G  G MG PG      +PG KG +G PG+   IG  GP   PG
Sbjct: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL---IGLIGP---PG 1426

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
             +GEKG+ G  G +G+PG  G  G  G  G LG  GPPG    PG +GP G  G  G  G
Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAG 1483

Query: 365  ERGDQGGKGDPGRPGRRGPPGEI 387
            ++GD G  G PG P   GPPGE+
Sbjct: 1484 QKGDSGLPGPPGSP---GPPGEV 1503


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  319 bits (818), Expect = 6e-87
 Identities = 176/362 (48%), Positives = 200/362 (55%), Gaps = 28/362 (7%)

Query: 255  PGPSGPKG------------YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGP 299
            PGP GP G             RG+ G +G  G PG  G  G QG  G  GPIG    PGP
Sbjct: 930  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGP 989

Query: 300  KGVPGFKGEKGEFGADGRKGAPG---LAGKNGTDGQKGKLGRIGPPGCKGDPG---NRGP 353
             G PG +G  G  G +G KG PG   ++GK+G  G +G  G  G PG +G PG     GP
Sbjct: 990  PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049

Query: 354  DGYPGEAGSPGERGDQGGKGD---PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGA 410
             G PG  GSPGERG  G  G    PGRPG +GPPG  G KG+ G +G  G  G  GV+G 
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 411  KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G PGP GP G PG  GD G  G PG  G KG+KG+ GP GP GL G VG  G  G  G 
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGE 529
            PGPRG QG  G+ G +G+RG PG  GP G  G PGP G+ G  G   P GP G PG +G 
Sbjct: 1170 PGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGP 1229

Query: 530  PGPR---GPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
             GP    GP+G  G  G  G  G KGE GE  +PGPPGE G  GP+G  G +GE GPPG 
Sbjct: 1230 QGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1289

Query: 587  PG 588
             G
Sbjct: 1290 AG 1291



 Score =  318 bits (816), Expect = 1e-86
 Identities = 177/381 (46%), Positives = 215/381 (56%), Gaps = 47/381 (12%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD------PGIEGPIGF---------PG 298
            +PGP+GP G  G+ G KG +GEPG+ G KG +G+      PG++GP+G          PG
Sbjct: 1112 LPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171

Query: 299  PKGVPGFKGEKGEFGADGRKGAP------GLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG 352
            P+G  G  G+KG+ GA G  G P      GL G  G  G+ G +G +GPPG  G  G +G
Sbjct: 1172 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231

Query: 353  PDGYPGEAGSPGERGDQGG---KGDPGRPGRRGPPGEIGA---KGSKGYQGNSGAPGSPG 406
            P+G  G  G PG  G  GG   KG+PG  G  GPPGE G    KG +G +G +G PG+ G
Sbjct: 1232 PNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAG 1291

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP---------KGEKGDPGPEGPRGLAG 457
              GAKG PG  GPKG PG  G PG  G PG  GP         KGE GDPG  GP G +G
Sbjct: 1292 PPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSG 1351

Query: 458  EVGNKGAKGDRGLPGP------RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG 511
            E G  G  G RG PG       +G +GA GE G +G  G  G  GP+G +G+PGP+G  G
Sbjct: 1352 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRG 1411

Query: 512  RPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGP 568
             PG    G +G PG  G+ GP GP G  G  GLKG+PG KGEKG P      GPPGE G 
Sbjct: 1412 IPG--PVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGE 1469

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
            +G RG+PG +G PG  GD G+
Sbjct: 1470 KGDRGLPGTQGSPGAKGDGGI 1490



 Score =  315 bits (807), Expect = 1e-85
 Identities = 172/361 (47%), Positives = 200/361 (55%), Gaps = 28/361 (7%)

Query: 256  GPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
            GP+GP+G RG +G       KG  G  G PG  G +G  G +GP+GFPGPKG PG  G+ 
Sbjct: 883  GPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG---PDGYPGEAGSPGER 366
            G  G  G++G  G  GK G  G  G +G  GP G  G  G RG   P G PGE G PG  
Sbjct: 943  GLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA 1002

Query: 367  GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
            G +G KGDPG  G  G  G  G +G  G +G  GA G+PG+KG +G  GP GP G PG R
Sbjct: 1003 GKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062

Query: 427  GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGE------VGNKGAKGDRGLPGPRGPQGA- 479
            G  GT G  G  G  G +G PGP G +G  GE       G  G +G  GLPGP GP G+ 
Sbjct: 1063 GSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSP 1122

Query: 480  --------LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG-RPGFSYPGPRGAP---GEK 527
                    +GEPG++GS+GD G+ GP G  G  GP G PG   G   PGPRG     G+K
Sbjct: 1123 GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQK 1182

Query: 528  GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDP 587
            G+ G RG  G  G  GL+G PG  GEKGE  D GP G PGP GPRG  GP G  GP G P
Sbjct: 1183 GDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1242

Query: 588  G 588
            G
Sbjct: 1243 G 1243



 Score =  303 bits (776), Expect = 4e-82
 Identities = 172/371 (46%), Positives = 204/371 (54%), Gaps = 37/371 (9%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKG---VPGFKGEKGEF 312
            G  GP+G +G+ G  G+ G  G+ G+KG+ G PG+ G  G  GPKG    PGF G  GE 
Sbjct: 808  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGP---PGCKGDPGNRGPDGYPGEAGSPGERGD- 368
            GA G  G PG  G+ G  G +G  G  GP   PG KG  G  GP G PGE G  G +G  
Sbjct: 868  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPV 927

Query: 369  --QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE---P 423
               G KG PG PG+ G PG  G +G  G+QG +G PG  GV G +G  G  GP GE   P
Sbjct: 928  GFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP 987

Query: 424  GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP 483
            G  G PG +G PG+ G +G KGDPGP+G  G  G  G +G  G+RGLPG +G  G  G  
Sbjct: 988  GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGE 1047

Query: 484  GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----GPRGAPGEKGE---------- 529
            G QG  G  G  G RG +G  GP G PGRPG   P    G +GAPGEKG           
Sbjct: 1048 GPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ 1107

Query: 530  -----PGPRGPEGGRGDFGLK---GEPGRKGEKGEPADPGPPGEPGPRGPRGVP---GPE 578
                 PGP GP G  G+ G K   GEPG+KG KG+  + GPPG PG +GP G P   G +
Sbjct: 1108 GPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGD 1167

Query: 579  GEPGPPGDPGL 589
            GEPGP G  G+
Sbjct: 1168 GEPGPRGQQGM 1178



 Score =  302 bits (773), Expect = 1e-81
 Identities = 160/348 (45%), Positives = 187/348 (53%), Gaps = 20/348 (5%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            + G  GP G +G+ G  G MG PG PG +G QG  G +GP G PG  G  G  GEKGE G
Sbjct: 1199 LQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPG 1258

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G  G PG AG  G  G++G+ G  GPPG  G PG +GP   PG+ G  G  G  G  G
Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGP---PGDDGPKGNPGPVGFPG 1315

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            DPG PG  GP G+ G  G KG  G+ G PG PG  G  G PGP G +G PG  G  G +G
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1375

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G+ G  G +G PG  GP G  G  G  G +G RG+PGP G QG  G  G+ G  G  G
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G  G PG KG+ G PG    G  G PGE+GE G RG  G +G  G KG+ G  G 
Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLI--GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGP 1493

Query: 554  KGEPADPGPPGEPGPRGPR---------------GVPGPEGEPGPPGD 586
             G    PGPPG PGP+GP+               G+PGP G PGPPG+
Sbjct: 1494 AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541



 Score =  300 bits (769), Expect = 3e-81
 Identities = 168/365 (46%), Positives = 196/365 (53%), Gaps = 37/365 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP GP G +G  GA G  G  G+PG +G  G  G  G  GFPG +G+PG +G  G  G 
Sbjct: 987  PGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG- 373
            +G +G PG  G   + G++G  G  GP G  G PG +GP G  GE G+PGE+G QG  G 
Sbjct: 1047 EGPQGPPGPVG---SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1103

Query: 374  -----------------DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
                              PG  G +G  GE G KGSKG +G +G PG PG++G  G PG 
Sbjct: 1104 DGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1163

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP---RGLAGEVGNKGAKGD------ 467
             G  GEPG RG  G  G  G +G +G    PGP GP   +GL G  G KG  GD      
Sbjct: 1164 AGGDGEPGPRGQQGMFGQKGDEGARGF---PGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220

Query: 468  RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGE 526
             G PGPRGPQG  G  G QG  G  G  G  G+ G+PG  G+PG PG     GP+G  GE
Sbjct: 1221 PGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGE 1280

Query: 527  KGE---PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            KGE   PG  GP G +G  G  G  G  G  G P DPGPPGEPGP G  GV G +GE G 
Sbjct: 1281 KGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGD 1340

Query: 584  PGDPG 588
            PG PG
Sbjct: 1341 PGQPG 1345



 Score =  300 bits (768), Expect = 4e-81
 Identities = 164/368 (44%), Positives = 196/368 (53%), Gaps = 22/368 (5%)

Query: 244  GECYKVSCLEIPGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK 300
            G+  +   L  PGP GP GY   RG KGA G  G  G  G+KG  G PG +G +G  G +
Sbjct: 739  GQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDR 798

Query: 301  GVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
            G  G  G +GE G +G KG  G  G  G  GQ G+ G++G PG  G PG +GP G  G  
Sbjct: 799  GEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858

Query: 361  GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGS------------KGYQGNSGAPGSPGVK 408
            G PG  G++G +G  G+PG RG  G  G +GS            KG  G  G PG PG +
Sbjct: 859  GFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGER 918

Query: 409  GAKGG------PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G +G       PGP+GP G PG+ G PG  G  G  G +G+ G PGP G  G  G  G  
Sbjct: 919  GPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET 978

Query: 463  GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPR 521
            G  G+RG PGP GP G  G PG  G  G  GD GP+G SG+ GP G  G PG    PG +
Sbjct: 979  GPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQ 1038

Query: 522  GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEP 581
            GAPG KG  GP+GP G  G  G +G  G  G  G P  PGP G PGP G +G PG +G  
Sbjct: 1039 GAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQ 1098

Query: 582  GPPGDPGL 589
            GP G  G+
Sbjct: 1099 GPAGRDGV 1106



 Score =  298 bits (763), Expect = 1e-80
 Identities = 170/378 (44%), Positives = 195/378 (51%), Gaps = 46/378 (12%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI------------EGPIGFPGPKGV 302
           PGP+G  G RG+ GA G  G PGEPG KG +G  G+             GP G PGP G 
Sbjct: 570 PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD 629

Query: 303 PGFKGEKGEF------------------GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGC 344
            G +GE GE                   G  G  G PG+AG +G  G KG +G  G PG 
Sbjct: 630 DGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGP 689

Query: 345 KGDPGNRGPDGYP---GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGA 401
            G  GN GP G P   G  G PGE+G QG  G  G PG  GPPG     G +G  G  GA
Sbjct: 690 PGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH---PGKEGQSGEKGA 746

Query: 402 PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGN 461
            G PG +G  G PGPRG KG  G RG  G+KG  G DG  G KGD G +G RG  G++G 
Sbjct: 747 LGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGP 806

Query: 462 KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF------ 515
           +G  G  G  G  GP G  G  G+ G +G  G  G  G  G+ GPKG  G PGF      
Sbjct: 807 RGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGE 866

Query: 516 -SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR-- 572
               G  G PG +G+ GP GP G RG  G  G+PG KG  G    PGPPGE GP+GP+  
Sbjct: 867 KGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 926

Query: 573 -GVPGPEGEPGPPGDPGL 589
            G PGP+G PGPPG  GL
Sbjct: 927 VGFPGPKGPPGPPGKDGL 944



 Score =  293 bits (749), Expect = 6e-79
 Identities = 165/362 (45%), Positives = 192/362 (53%), Gaps = 44/362 (12%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV---PGFKGEKGE 311
            PGP GP G  G+KGA      PGE G +G  G  G++GP+G PGP G    PG  G+KGE
Sbjct: 1077 PGPQGPPGPAGEKGA------PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G  G+KG+ G  G+NG  G  G  G +G PG  G  G  GP G   + G  G++GD+G 
Sbjct: 1131 IGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG---QQGMFGQKGDEGA 1187

Query: 372  KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT 431
            +G PG      PPG IG +G  G  G  G  G  G  G  G PGPRGP+G  G  G  G 
Sbjct: 1188 RGFPG------PPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGP 1241

Query: 432  KGSPGSDGPKGEKGD------PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK 485
             GS GS G  GEKG+      PGP G  G+ G  G +G KG+ G PG  GP GA G PG 
Sbjct: 1242 PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGD 1301

Query: 486  QGSRGDPGDAGPRGDSGQP---------------GPKGDPGRPGFSYPGPRGAPGEKGEP 530
             G +G+PG  G  GD G P               G  GDPG+PG   PGP G  G  G P
Sbjct: 1302 DGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG--PPGPSGEAGPPGPP 1359

Query: 531  GPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE---GEPGPPGDP 587
            G RGP G  G  G +GE G KGE G    PG  G  GP+GP G PGPE   G PGP G+ 
Sbjct: 1360 GKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQ 1419

Query: 588  GL 589
            GL
Sbjct: 1420 GL 1421



 Score =  291 bits (746), Expect = 1e-78
 Identities = 163/366 (44%), Positives = 190/366 (51%), Gaps = 31/366 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG---------PKGVPG 304
            I G  GP G RG  G +G  G  G PG KG +G  G  GP+G PG         P G+PG
Sbjct: 1016 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
              G +G  G  G KGAPG  G  G  G+ G  G +G PG  G  G+ G DG  GE G PG
Sbjct: 1076 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1135

Query: 365  ERGDQGGKGDPGRPG------------------RRGPPGEIGAKGSKGYQGNSGAPGSPG 406
            ++G +G KG+ G PG                    GP G+ G  G KG +G  G PG PG
Sbjct: 1136 QKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              G +G PGP G KGE G  G  G  G PG  GP+G  G  GP+GP G  G VG  G KG
Sbjct: 1196 PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKG 1255

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPG 525
            + G  G  GP G  G  G +G RG+ G+AGP G +G PG KG PG  G    PGP G PG
Sbjct: 1256 EPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPG 1315

Query: 526  E---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
            +    GEPGP G +G  GD G  G+PG+ G  G   + GPPG PG RGP G  G EG  G
Sbjct: 1316 DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG 1375

Query: 583  PPGDPG 588
              G  G
Sbjct: 1376 EKGAKG 1381



 Score =  291 bits (744), Expect = 2e-78
 Identities = 169/359 (47%), Positives = 190/359 (52%), Gaps = 28/359 (7%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG------PIGFPGPKGVPGFKGE 308
            PG  G  G  G  G KGNMG  GEPG  G+QG+PG +G      PIG PG KG  G  G 
Sbjct: 663  PGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGL 722

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR------------GPDGY 356
             G  GAD   G PG  GK G  G+KG LG  GP G  G PG R            G  G 
Sbjct: 723  AGLPGAD---GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779

Query: 357  PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
             GE G PG +GD G KGD G  G+ GP GE G +G KG  G +G PG  G  G KG  G 
Sbjct: 780  KGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGV 839

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEK------GDPGPEGPRGLAGEVGNKGAKGDRGL 470
             G  G PGR+G  G+ G PG  G  GEK      G PGP G RG  G  G++GA+G  G 
Sbjct: 840  PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 899

Query: 471  PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGE 529
            PGP+G  G  G PG  G RG  G  GP G  G  GP G PG+ G   +PG RG  G +G+
Sbjct: 900  PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 959

Query: 530  PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             GP GP G  G  G  GE G  GE+G P  PGPPGE G  G  G  G +G+PGP G  G
Sbjct: 960  TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISG 1018



 Score =  280 bits (716), Expect = 4e-75
 Identities = 172/448 (38%), Positives = 218/448 (48%), Gaps = 75/448 (16%)

Query: 206 STPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEI----------P 255
           S P+E    ++   +P  T+I + +IN       H AYGE  +     +          P
Sbjct: 395 SPPNE----EFGPGVPAETDITETSING------HGAYGEKGQKGEPAVVEPGMLVEGPP 444

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV----------PGF 305
           GP+GP G  G  G +G  G PG+PG +G  G PG+ G  G PGP G            G 
Sbjct: 445 GPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGS 504

Query: 306 KGE--------------------KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCK 345
           KG                     +G  G  G  G PG  G  G+ G KG+ G  GP G +
Sbjct: 505 KGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPR 564

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRR------GPPGEIGAKGSKGYQGNS 399
           G  G  GP G PG+ G PG  G +G  G+PG  G R      G PG+ G +G +G QG  
Sbjct: 565 GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPP 624

Query: 400 GAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEV 459
           G PG  G++G  G  GPRG  GE G RG  G +G+PG+ G  G  G  GP GP+G  G  
Sbjct: 625 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684

Query: 460 GNKGAKGDRGLPGPR---GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-- 514
           G  G  G +G PGP+   GPQG +G PG++G +G PG AG  G  G PG  G  G+ G  
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744

Query: 515 -----------FSYPGPRGAPGEKGEPGPRGPEGGRGDF---GLKGEPGRKGEKGEPADP 560
                        YPGPRG  G  G  G +G +G +G+    G KG+ G KG++GE    
Sbjct: 745 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804

Query: 561 GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           GP GE GP GP+G  GP G+PGP G  G
Sbjct: 805 GPRGEDGPEGPKGRAGPTGDPGPSGQAG 832



 Score =  231 bits (588), Expect = 3e-60
 Identities = 147/331 (44%), Positives = 170/331 (51%), Gaps = 32/331 (9%)

Query: 274 GEPGEPGQKGRQG--DPG--IEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGT 329
           G  GE GQKG     +PG  +EGP   PGP G  G  G  G  G  G  G PG  G  G 
Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGP---PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGR 476

Query: 330 DGQKGKLGRIGPPGCKGD-PGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIG 388
            G  G  G  GPPG     P   G DG  G   S  E   Q       R   RGPPG +G
Sbjct: 477 PGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAIL-QQARIALRGPPGPMG 535

Query: 389 AKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG---EPGRRGDPGTKGSPGSDGPKGEKG 445
             G  G     G PGS G KG  G PGP+GP+G    PG  G PG +G PG+DG +G  G
Sbjct: 536 LTGRPG---PVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592

Query: 446 DPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPG 505
           +PG +G RG  G  G  G KG RG    RGPQG  G PG  G RG+ G+ GPRG  G+ G
Sbjct: 593 EPGAKGDRGFDGLPGLPGDKGHRG---ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAG 649

Query: 506 PKGDPGRPGFSYPGPRGAPGEKGEPGPRG---PEGGRGDFGLKGEPGRKGEKGEPADPGP 562
           P+G          GPRG PG  G+PG  G   P G +G+ G +GEPG  G++G   +PGP
Sbjct: 650 PRG--------LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG---NPGP 698

Query: 563 PGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
            G PGP+GP G PG +G  G PG  GL   D
Sbjct: 699 QGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729



 Score =  177 bits (448), Expect = 5e-44
 Identities = 92/195 (47%), Positives = 112/195 (57%), Gaps = 3/195 (1%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G +G  G  GA+G  GE G  G+ G +G PG  GP+G  GP G PG +G +G  G 
Sbjct: 1356 PGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP 1415

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G +G PG AG+   DG  G +G  G PG KGDPG++G  G+PG  G  G  G+QG KGD
Sbjct: 1416 VGEQGLPGAAGQ---DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGD 1472

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G PG +G PG  G  G  G  G  G PG PG+ G +G  G +G  G  G++GD G  G 
Sbjct: 1473 RGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532

Query: 435  PGSDGPKGEKGDPGP 449
            PGS GP GE   P P
Sbjct: 1533 PGSPGPPGEVIQPLP 1547



 Score =  112 bits (279), Expect = 2e-24
 Identities = 66/143 (46%), Positives = 78/143 (54%), Gaps = 21/143 (14%)

Query: 254  IPGPSGPKGY---RGQKGAKGNMGEPG------EPGQKGRQGDPGIEGPIGFPGPKGVPG 304
            IPGP G +G     GQ G  G MG PG      +PG KG +G PG+   IG  GP   PG
Sbjct: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGL---IGLIGP---PG 1465

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
             +GEKG+ G  G +G+PG  G  G  G  G LG  GPPG    PG +GP G  G  G  G
Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAG 1522

Query: 365  ERGDQGGKGDPGRPGRRGPPGEI 387
            ++GD G  G PG P   GPPGE+
Sbjct: 1523 QKGDSGLPGPPGSP---GPPGEV 1542


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  318 bits (814), Expect = 2e-86
 Identities = 176/371 (47%), Positives = 203/371 (54%), Gaps = 39/371 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP GP G    KG +G  G  G PG  GR G+PG  G  G  G  G+PG +G+ GE G 
Sbjct: 1283 PGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGP 1342

Query: 315  DGRKGAPGLAGK------NGTDGQKGKLGRIGPPGCK---GDPGNRGPDGYPGEA--GSP 363
             G KG PG  G+       G  G+KG  G  GPPG +   GDPG RGP G PG A  G  
Sbjct: 1343 RGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDK 1402

Query: 364  GERGDQGGKGD------------PGRPGRRGPPGEIGAKGSKGYQGNS--GAPGSPGVKG 409
            G+RG++G  G             PG PG  GP G +G  G KG +G+S  GAPG PG  G
Sbjct: 1403 GDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPG 1462

Query: 410  AKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRG 469
            + G  GPRGP G  G +GD G  G  G  G KGE+G PGP G RGL G  G  GAKG  G
Sbjct: 1463 SPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEG 1522

Query: 470  LPGPRGPQGALGEPGKQGS-----------RGDPGDAGPRGDSGQPGPKGDPGRPGFSYP 518
             PGP G QG  GEPG+ G            +G+ GD GP G  G  G +G+ G PG   P
Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLP 1582

Query: 519  GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE 578
            G    PG KG+PG RGP G  G  G  G+ G  GEKG+P  PGPPG  GPRG  G  G +
Sbjct: 1583 GD---PGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEK 1639

Query: 579  GEPGPPGDPGL 589
            G+ GPPGDPGL
Sbjct: 1640 GDEGPPGDPGL 1650



 Score =  307 bits (786), Expect = 3e-83
 Identities = 168/355 (47%), Positives = 203/355 (57%), Gaps = 23/355 (6%)

Query: 255  PGPSGPKGYRGQKGAKGNM--------GEPGEPGQKGRQGDPGIEGPIG---FPGPKGVP 303
            PGP GP G  G+KG KG+         G+PG PG++G +G PG  GP G   FPGP G  
Sbjct: 1432 PGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY--PGEAG 361
            G KGE+G  G  G +G PG+AG+ G  G +G  G  G  G KG+PG  G      P  AG
Sbjct: 1492 GEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAG 1551

Query: 362  SPGERGD---QGGKGDPGRPGRRGPPGEI--GAKGSKGYQGNSGAPGSPGVKGAKGGPGP 416
              GE+GD    G +G  G  G RGPPG +  G  G KG  G+ G  G  G  G  G  GP
Sbjct: 1552 PKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP 1611

Query: 417  RGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP 476
             G KG+PGR G PG  G  G DG  GEKGD GP G  GL G+ G +G +G  G+ GP G 
Sbjct: 1612 PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGE 1671

Query: 477  QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPR--GAPGEKGEPGPRG 534
            +G  G+PG+ G  G PG +GP+GD G+PGP G PGR   + PG R  G PG++G+ GPRG
Sbjct: 1672 KGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG 1731

Query: 535  PEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
            P   +GD GL G PG +G +G    PGP G+PG RGP G  G  G PG  G  GL
Sbjct: 1732 P---KGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGL 1783



 Score =  304 bits (779), Expect = 2e-82
 Identities = 182/442 (41%), Positives = 213/442 (48%), Gaps = 107/442 (24%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
            GP G +G+ G  G  G  GE G PG  G +G PG+ G  G  GP+G PG  G +GE G  
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 316  GRKGAPGLAGKN--GTDGQKGKLGRIGP--------------------PGCKGDPGNRGP 353
            GR G P + G    G  G+KG +G  GP                    PG KGDPG+RGP
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 354  DGYPGEAGSPGERGDQGGKGDPGRPGRRGP------PGEIGAKGSKGYQGNSGAPGSPGV 407
             G  G AG PG+ G  G KGDPGRPG  GP       GE+G KG +G  G+ G PG  G 
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 408  KGAKGGPGPRGPKGEPGRRGDPGT---KGSPGSDGPKGEKGDPGP--------------- 449
            +G +G PG RGP GE G +GDPG     GSPGS GPKG++G+PGP               
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 450  ----------EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP-- 497
                      EGPRG  G+ G  GA G+RG+ G RGP G  G+PG +G  G+ GD GP  
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPG 1776

Query: 498  -------------------------------------RGDSGQPGPKGDPGRPGF----S 516
                                                 RG+ G PGP G PG PG      
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDG 1836

Query: 517  YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG------PPGEPGPRG 570
             PG  G  GE G+PG  G +G +GD G  G  GR G KGE   PG      PPG PGP G
Sbjct: 1837 KPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVG 1896

Query: 571  P--RGVPGPEGEPGPPGDPGLT 590
            P  +G PG  G  GP GD G T
Sbjct: 1897 PPGQGFPGVPGGTGPKGDRGET 1918



 Score =  298 bits (762), Expect = 2e-80
 Identities = 179/412 (43%), Positives = 218/412 (52%), Gaps = 64/412 (15%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP---------- 303
            +PG  G  G+ GQ G +G MG+PG  G++G  G PG EG    PGP G P          
Sbjct: 2396 LPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREG---IPGPLGPPGPPGSVGPPG 2452

Query: 304  --GFKGEKGEFGAD-----GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY 356
              G KG+KG+ G       G +G PG+ G++G  GQ+G  G  GPPG +G+ G +G  G 
Sbjct: 2453 ASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGS 2512

Query: 357  PGEAGSPGER-------GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKG 409
             G  G  G+        G +G KGD G  G RG  G+ G +G  G  G+ G+ G PG KG
Sbjct: 2513 AGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572

Query: 410  AKGGPGPR---GPKGEPGRRGDPGTKGSPGSDGP---KGEKGDPGPEGPRGLAGEVGNKG 463
            + G PG R   GP+G+PG  G PG  GSPG DG    +GEKGD G  GPRGL GE G KG
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKG 2632

Query: 464  A------KGDRGLPGP------RGPQGALGEPGKQGSRGDPGD---AGPRGD---SGQPG 505
            A      KGD+G  GP       G +G +GEPG  G  G PG     GP+GD    GQPG
Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPG 2692

Query: 506  PKGDPGRPG-------FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGE-- 556
            PKGD G  G         +PGP G  G  G PGP G  G RG  GL+G+ G +G  GE  
Sbjct: 2693 PKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERV 2752

Query: 557  PADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRET----CGC 604
               PG PG PG RG +G PGP G  G  G+  LTE D+  +VR+     C C
Sbjct: 2753 VGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQHCAC 2804



 Score =  297 bits (760), Expect = 3e-80
 Identities = 174/370 (47%), Positives = 196/370 (52%), Gaps = 43/370 (11%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP GPK    + G  G  GE G PG KG +G+PG  G  G  G +GVPG KG++GE G 
Sbjct: 2087 PGPPGPKVSVDEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGP 2145

Query: 315  DGRKGAPGLAGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G+ G PGL G+ G  G +GK    G  GPPG  G  G+ GP G PG AG  G +G  G 
Sbjct: 2146 RGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGL 2205

Query: 372  KGDPGR---PGRR--------GPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPK 420
            KG+PG    PGR         G PG  G  G  G QG+ G PG  G  G  G PG  G  
Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265

Query: 421  GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG------------------PRGLAGE-VGN 461
            G+ G RG PG  GSPG  GP G KG+PGP G                  P GLAG+ VG 
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 462  KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPR 521
             GAKGDRGLPGPR      GE G+ G  G+PGD G  G  G PGPKG  G PG   PG  
Sbjct: 2326 PGAKGDRGLPGPR------GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSP 2379

Query: 522  GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE---PGPRGPRGVPGPE 578
            G PG  G  G  G  G  G  G+ G PG+ G +GE   PGP GE    GP G  G+PGP 
Sbjct: 2380 GPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439

Query: 579  GEPGPPGDPG 588
            G PGPPG  G
Sbjct: 2440 GPPGPPGSVG 2449



 Score =  288 bits (736), Expect = 2e-77
 Identities = 162/354 (45%), Positives = 193/354 (54%), Gaps = 16/354 (4%)

Query: 252  LEIPGPSGPK---GYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            L +PG  GPK   G RG  G  G  G PG+ G  G +GDPG  GP G  GP+G  G  GE
Sbjct: 1579 LVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE 1638

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
            KG+ G  G  G PG AG+ G  G  G  G +G  G +GDPG  G +G PG +G  G+RG+
Sbjct: 1639 KGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE 1698

Query: 369  QGGKGDPGR-----PGRR--GPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKG 421
             G  G PGR     PG R  G PG+ G +G +G +G+ G PG+PG +G +G  GP GP+G
Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758

Query: 422  EPGRRGDPGTKGS---PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQG 478
            +PG RG  G KG    PG DG  G  G PG  GP G  G  G  G  G  GLPG RG QG
Sbjct: 1759 DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQG 1818

Query: 479  ALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRGPEG 537
              G  G  G  G PG+ G  G +G+ G  GDPG  G     G  GA G +G  GP+G  G
Sbjct: 1819 LPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERG 1878

Query: 538  GRGDFGLKGEPGRKGEKGEPAD--PGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
              G  G +G PG  G  G P    PG PG  GP+G RG  G +GE G PG+ GL
Sbjct: 1879 APGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932



 Score =  285 bits (729), Expect = 1e-76
 Identities = 170/398 (42%), Positives = 199/398 (50%), Gaps = 66/398 (16%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPG--------------------------------- 280
            +PG +GPKG RG+ G+KG  G PGE G                                 
Sbjct: 1905 VPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWD 1964

Query: 281  ------------QKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLA---- 324
                        ++G +GD G +GP G  GP G PG +G KG+ G  G +G PGLA    
Sbjct: 1965 ESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGER 2024

Query: 325  ---GKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRR 381
               G +G  G+ GK G  G PG  G  G  G  G  GE G  GERG+QG  G PG PG  
Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTP 2084

Query: 382  GPPGEIGAKGSKGYQGN--SGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439
            GPPG  G K S    G   SG  G PG+KGAKG PG  G +G  G RG PG KG  G  G
Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG 2144

Query: 440  PKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG 499
            P+G+ G+PG  G RG+AG  G  G +G R   GP GP G  G+PG  G+ G  G AGP+G
Sbjct: 2145 PRGQDGNPGLPGERGMAGPEGKPGLQGPR---GPPGPVGGHGDPGPPGAPGLAGPAGPQG 2201

Query: 500  DSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGE---------PGR 550
             SG  G  G+ G PG    GP GA G  G PGP G  G +G  GL G+         PGR
Sbjct: 2202 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR 2261

Query: 551  KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G  G+  D G PG PG  G  G  GP+GEPGP G PG
Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPG 2299



 Score =  282 bits (721), Expect = 1e-75
 Identities = 165/374 (44%), Positives = 196/374 (52%), Gaps = 44/374 (11%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQ-----KGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
            PG +GP G +G  G KG  GE G PG+      G  G PG  GP G  GP+G PG  G+ 
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV 2250

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA--GSPGERG 367
            GE G  G  G  G +GK+G  G  G  G  G PG  G  G  GP G PG+A  G PG +G
Sbjct: 2251 GETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKG 2310

Query: 368  DQGGKGD-----PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE 422
            ++G  G       G PG +G  G  G +G KG  G +G PG PG  G KG PGP+G KG+
Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 423  PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482
            PG  G PG+ G PG  G KG+ G PG  G  G+ G  G  G +G+ G PGP G +G  G 
Sbjct: 2371 PGV-GVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGP 2429

Query: 483  PGKQGSRGDPGDAGPRGDSGQPGP---KGDPGRPGFSYPGPRGAPGEKGEPGPRGPE--- 536
            PG++G  G  G  GP G  G PG    KGD G PG   PGPRG   E+GEPG RG +   
Sbjct: 2430 PGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRG---ERGEPGIRGEDGRP 2486

Query: 537  GGRGDFGLKGEPGRKGEKGEPAD-------------------PGP---PGEPGPRGPRGV 574
            G  G  GL G PG +GE+GE  D                   PGP    G+ G RGPRG+
Sbjct: 2487 GQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGL 2546

Query: 575  PGPEGEPGPPGDPG 588
             G +G  G  GDPG
Sbjct: 2547 DGDKGPRGDNGDPG 2560



 Score =  281 bits (720), Expect = 1e-75
 Identities = 171/410 (41%), Positives = 204/410 (49%), Gaps = 76/410 (18%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G  G RG  G  G  G PG+ G  G +GDPG  GP G  GP+G  G  GEKG+ G 
Sbjct: 1585 PGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGP 1644

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G PG AG+ G  G  G  G +G  G +GDPG  G +G PG +G  G+RG+ G  G 
Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704

Query: 375  PGR-----PGRR--GPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRG 427
            PGR     PG R  G PG+ G +G +G +G+ G PG+PG +G +G  GP GP+G+PG RG
Sbjct: 1705 PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764

Query: 428  DPGTKGS---PGSDGPKGEKGDPG---PEGPRGLAGEVGNKGA------KGDRGLPGPRG 475
              G KG    PG DG  G  G PG   P GP G AG+ G+ G       +G++GLPGP G
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824

Query: 476  PQGALGEPG---------KQGSRGDPG---------DAGPRGDSGQPGPKGDPGRPGFSY 517
            P G  G+PG         K G  GDPG         D+G  G  G+ GPKG+ G PG   
Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 518  P-GPRGAPGEKGEPGPRGP--EGGRGDFGLKGEPGRKGEKGEPADPGPPGEPG------- 567
            P GP G PG  G PG   P   GG G  G +GE G KGE+G P + G  GEPG       
Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDR 1944

Query: 568  -----------------------------PRGPRGVPGPEGEPGPPGDPG 588
                                         P   RG  G  GE GPPG  G
Sbjct: 1945 LLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEG 1994



 Score =  272 bits (695), Expect = 1e-72
 Identities = 174/466 (37%), Positives = 205/466 (43%), Gaps = 132/466 (28%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKG----- 310
            GP GPKG  G  GA G  G  G  G  G QGDPG+ GP G  G +G PG  G  G     
Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787

Query: 311  -------EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------RGPDGYP 357
                     GA G+ G PG  G  G  G++G  G  GPPG  G PG        G +G P
Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847

Query: 358  GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQG-----------NSGAPGSPG 406
            G+ G  G +G++G  G  GR GR GP GE GA G  G QG             G PG PG
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPG 1907

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGS----------------------------- 437
              G KG  G  G KGE G  G+ G +G PGS                             
Sbjct: 1908 GTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESS 1967

Query: 438  ----------DGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP----------- 476
                       GPKG+ G+ GP G  G  G  G +G KGDRG PGP+GP           
Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027

Query: 477  --------------------QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
                                 G +GE G+ G RG+ G+ G RG+ G+ GP G PG PG  
Sbjct: 2028 GPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPP 2087

Query: 517  YP------------------GPRGAPGEKGEPGPRGPEGGRGDFGL------KGEPGRKG 552
             P                  GP G  G KGEPG  G +G +GD G+      +GEPG +G
Sbjct: 2088 GPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147

Query: 553  EKGEPADP------GPPGEPGPRGPRGVPGP---EGEPGPPGDPGL 589
            + G P  P      GP G+PG +GPRG PGP    G+PGPPG PGL
Sbjct: 2148 QDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGL 2193



 Score =  261 bits (667), Expect = 2e-69
 Identities = 168/420 (40%), Positives = 194/420 (46%), Gaps = 94/420 (22%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  G  G RG++G  G  G PG PG+ G  G PG+ G  G PG  G  G KGEKG+ GA
Sbjct: 1805 PGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGA 1864

Query: 315  DGRKGAPGLAGKNGT------DGQKGKLGRIGPPG--CKGDPGNRGPDGYPGEAGSPGER 366
             GR+G  G  G+ G        G  G  G +GPPG    G PG  GP G  GE GS GE+
Sbjct: 1865 SGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQ 1924

Query: 367  GDQGGKGDPGRPG---------------------------------------RRGPPGEI 387
            G  G +G  G PG                                       RRGP G+ 
Sbjct: 1925 GLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984

Query: 388  GAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP-------KGEPG------RRGDPGTKGS 434
            G +G  G +G  G PG  G+KG +G PGP+GP       +G PG        G PG  G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044

Query: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGP-----------------Q 477
            PG  G  GE G PG  G RG  GE G +G  G  GLPG  GP                  
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104

Query: 478  GALGEPGKQGSRGDPG---DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
            G  G PG +G++G+PG   D GP+GD G PG KGD G PG     PRG  G  G PG RG
Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPG-----PRGQDGNPGLPGERG 2159

Query: 535  PEGGRGDFGLKGEPGRKGEKGEPADPGPPGEP------GPRGPRGVPGPEGEPGPPGDPG 588
              G  G  GL+G  G  G  G   DPGP   P      GP GP+G  G +GEPG  G PG
Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGP---PGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216



 Score =  254 bits (649), Expect = 2e-67
 Identities = 160/358 (44%), Positives = 178/358 (49%), Gaps = 75/358 (20%)

Query: 299  PKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPG 358
            PKG  G  GE G  G  G  G PGL G+ G  G +G  G     G +G PG  G  G PG
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 359  EAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS------PGVKGAKG 412
             AG+PG  G  G KG PG PG RG PGE G +G KG     GAPG       PG+ G KG
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKG---EPGAPGQVIGGEGPGLPGRKG 1368

Query: 413  GPGPRGPKGEPGRRGDPGTKGSPGSDGP--KGEKGDPGPEGPRGLAGEVG-NKGAKGDRG 469
             PGP GP G  G  GDPG +G PG  G   KG+KGD G  GP G  GE G   G  G  G
Sbjct: 1369 DPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPG-PGEGGIAPGEPGLPG 1427

Query: 470  LPGPRGPQGALGEPGKQGSRGD--------------PGDAGPRGDSGQPGPKGDPGRPGF 515
            LPG  GPQG +G PGK+G +GD              PG+ GPRG  G  GPKGD G    
Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRG---- 1483

Query: 516  SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPG------------RKGEKGEPADPGPP 563
             +PGP G  GEKGE GP GP G RG  G+ G PG            R+GEKGEP  PG P
Sbjct: 1484 -FPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 564  --------------GEPGPRGPRGV-----------------PGPEGEPGPPGDPGLT 590
                          G+ GP GPRG                  PGP+G+PG  G  GLT
Sbjct: 1543 AVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLT 1600



 Score = 47.4 bits (111), Expect = 6e-05
 Identities = 43/151 (28%), Positives = 68/151 (45%), Gaps = 9/151 (5%)

Query: 610 RCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG 669
           R  A D+VF++D S SIG +NF   ++F+  +V      A    S  G R   VQYS + 
Sbjct: 33  RLYAADIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAA----SAQGVRFATVQYSDDP 88

Query: 670 TFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRL-IKESRRQKTRVFAV 728
             E      + + S      A++ L +  G T T +A+    D + + +  R       +
Sbjct: 89  RTE---FGLDALGSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCI 145

Query: 729 VITDGRHDPRDDDLNLRALCDRDVTVTAIGI 759
           +ITDG+     D    R L  + V + A+GI
Sbjct: 146 LITDGKSQDLVDTAAQR-LKGQGVKLFAVGI 175


>gi|55743106 alpha 3 type VI collagen isoform 5 precursor [Homo
            sapiens]
          Length = 2971

 Score =  317 bits (812), Expect = 3e-86
 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%)

Query: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 1729 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1782

Query: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 1783 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 1839

Query: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 1840 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 1896

Query: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 1897 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 1953

Query: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 1954 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2013

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 2014 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2073

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 2074 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2133

Query: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 2134 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2192

Query: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 2193 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2250

Query: 672  EAIQLDDERIDSLSSFKEAVKNLE 695
            E    D +R    S   + +KNL+
Sbjct: 2251 EIRFADSKR---KSVLLDKIKNLQ 2271



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%)

Query: 613  ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672
            A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 1228 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1280

Query: 673  AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727
               L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 1281 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1338

Query: 728  VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
            V++  G+     DD++  A   R   + ++G+GD   ++ E + +
Sbjct: 1339 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1380



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673
           D++F++D S ++G TNF   ++FV+N+VN L  I  D       RVG+VQ+S     E +
Sbjct: 433 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 486

Query: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724
           +     + D L   ++    L+   G G  T SAL + Y     E+   + R
Sbjct: 487 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 534



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668
           D++F+ID S + G  NF +  +F++N++ +L      P      RVGVVQ+S E
Sbjct: 36  DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 83



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 239 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 292

Query: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 293 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 345

Query: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E +
Sbjct: 346 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 389



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 2412 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2470

Query: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700
               +   +++ SL+ +    K +++++ G
Sbjct: 2471 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2499



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 612  GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
            G  DVVF+ID S+S G   F   +  +  +V+ L     D   +T TRV V+Q+S +   
Sbjct: 1024 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL-----DVGFDT-TRVAVIQFSDDPKV 1076

Query: 672  EAIQLDDERIDSLSSFKEAV--KNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVV 729
            E +       D + +  + +  K    I  G       +  + R +     +    F V+
Sbjct: 1077 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 1136

Query: 730  ITDGRHDPRDDD 741
            I+ G+ D   DD
Sbjct: 1137 ISSGKSDDEVDD 1148


>gi|55743098 alpha 3 type VI collagen isoform 1 precursor [Homo
            sapiens]
          Length = 3177

 Score =  317 bits (812), Expect = 3e-86
 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%)

Query: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 1935 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1988

Query: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 1989 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 2045

Query: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 2046 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 2102

Query: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 2103 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 2159

Query: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 2160 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 2219

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 2220 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 2279

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 2280 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 2339

Query: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 2340 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 2398

Query: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 2399 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 2456

Query: 672  EAIQLDDERIDSLSSFKEAVKNLE 695
            E    D +R    S   + +KNL+
Sbjct: 2457 EIRFADSKR---KSVLLDKIKNLQ 2477



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%)

Query: 613  ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672
            A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 1434 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 1486

Query: 673  AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727
               L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 1487 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 1544

Query: 728  VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
            V++  G+     DD++  A   R   + ++G+GD   ++ E + +
Sbjct: 1545 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 1586



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 35/112 (31%), Positives = 56/112 (50%), Gaps = 12/112 (10%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673
           D++F++D S ++G TNF   ++FV+N+VN L  I  D       RVG+VQ+S     E +
Sbjct: 639 DIIFLLDGSANVGKTNFPYVRDFVMNLVNSLD-IGND-----NIRVGLVQFSDTPVTEFS 692

Query: 674 IQLDDERIDSLSSFKEAVKNLEWIAG-GTWTPSALKFAYDRLIKESRRQKTR 724
           +     + D L   ++    L+   G G  T SAL + Y     E+   + R
Sbjct: 693 LNTYQTKSDILGHLRQ----LQLQGGSGLNTGSALSYVYANHFTEAGGSRIR 740



 Score = 40.8 bits (94), Expect = 0.005
 Identities = 41/157 (26%), Positives = 67/157 (42%), Gaps = 14/157 (8%)

Query: 609 KRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668
           K   A D++F++DSS +IG  +F L + F+ +VV  L         E      +VQ++  
Sbjct: 33  KNGAAADIIFLVDSSWTIGEEHFQLVREFLYDVVKSLAV------GENDFHFALVQFNGN 86

Query: 669 GTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQK----TR 724
              E + L+  R  +       + N+ +I G   T   L++     + ++   +      
Sbjct: 87  PHTEFL-LNTYR--TKQEVLSHISNMSYIGGTNQTGKGLEYIMQSHLTKAAGSRAGDGVP 143

Query: 725 VFAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGD 761
              VV+TDG H      L    L   DV V AIG+ D
Sbjct: 144 QVIVVLTDG-HSKDGLALPSAELKSADVNVFAIGVED 179



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 20/54 (37%), Positives = 32/54 (59%), Gaps = 6/54 (11%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668
           D++F+ID S + G  NF +  +F++N++ +L      P      RVGVVQ+S E
Sbjct: 242 DIIFLIDGSNNTGSVNFAVILDFLVNLLEKL------PIGTQQIRVGVVQFSDE 289



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 445 DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 498

Query: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 499 FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 551

Query: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E +
Sbjct: 552 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 595



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 2618 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2676

Query: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700
               +   +++ SL+ +    K +++++ G
Sbjct: 2677 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2705



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 612  GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
            G  DVVF+ID S+S G   F   +  +  +V+ L     D   +T TRV V+Q+S +   
Sbjct: 1230 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL-----DVGFDT-TRVAVIQFSDDPKV 1282

Query: 672  EAIQLDDERIDSLSSFKEAV--KNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVV 729
            E +       D + +  + +  K    I  G       +  + R +     +    F V+
Sbjct: 1283 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 1342

Query: 730  ITDGRHDPRDDD 741
            I+ G+ D   DD
Sbjct: 1343 ISSGKSDDEVDD 1354


>gi|240255535 alpha 3 type VI collagen isoform 4 precursor [Homo
            sapiens]
          Length = 2570

 Score =  317 bits (812), Expect = 3e-86
 Identities = 205/564 (36%), Positives = 271/564 (48%), Gaps = 29/564 (5%)

Query: 140  NMTEQIRQDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIR-LFAVAPNQNLKE 198
            N   Q   D  K  +HF    TDG         +   +E  R+EG+R L  V   + +  
Sbjct: 1328 NKFRQSSPDSVKVVIHF----TDG--ADGDLADLHRASENLRQEGVRALILVGLERVVNL 1381

Query: 199  QGLRDIASTPHELYRNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIP-GP 257
            + L  +      +Y       L D   +D +   ++  + +    G   K S      GP
Sbjct: 1382 ERLMHLEFGRGFMYDRPLRLNLLD---LDYELAEQLDNIAEKACCGVPCKCSGQRGDRGP 1438

Query: 258  SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317
             G  G +G  G  G  G PG+ G  G +G PG+ G  GF   +G PG +G KG  G  G 
Sbjct: 1439 IGSIGPKGIPGEDGYRGYPGDEGGPGERGPPGVNGTQGF---QGCPGQRGVKGSRGFPGE 1495

Query: 318  KGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGR 377
            KG  G  G +G DG+ G  G  G  G KG+PG RG  G  GE G   ERGD G +GDPG 
Sbjct: 1496 KGEVGEIGLDGLDGEDGDKGLPGSSGEKGNPGRRGDKGPRGEKG---ERGDVGIRGDPGN 1552

Query: 378  PGR----RGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            PG+    RGP GE G  G  G  G  G PG PG  G  GG G RGP G  G +G PG  G
Sbjct: 1553 PGQDSQERGPKGETGDLGPMGVPGRDGVPGGPGETGKNGGFGRRGPPGAKGNKGGPGQPG 1612

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
              G  G +G +G  GP GP GL GE G  G +G  G  G  G +G  G  G++G  G+PG
Sbjct: 1613 FEGEQGTRGAQGPAGPAGPPGLIGEQGISGPRGSGGAAGAPGERGRTGPLGRKGEPGEPG 1672

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE 553
              G  G+ G  G  GD GR G    G RG  GE+G PG  GP+G  G+ GL G  G KG 
Sbjct: 1673 PKGGIGNRGPRGETGDDGRDGVGSEGRRGKKGERGFPGYPGPKGNPGEPGLNGTTGPKGI 1732

Query: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKRCGA 613
            +G   + GPPG  G +G  G PGP G  G  GD  + +C ++  +++ C CC     C  
Sbjct: 1733 RGRRGNSGPPGIVGQKGDPGYPGPAGPKGNRGD-SIDQCALIQSIKDKCPCCYGPLECPV 1791

Query: 614  L--DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
               ++ F +D+SE +    F   ++ V+++VN L     +     G RV VV Y++E T 
Sbjct: 1792 FPTELAFALDTSEGVNQDTFGRMRDVVLSIVNDL--TIAESNCPRGARVAVVTYNNEVTT 1849

Query: 672  EAIQLDDERIDSLSSFKEAVKNLE 695
            E    D +R    S   + +KNL+
Sbjct: 1850 EIRFADSKR---KSVLLDKIKNLQ 1870



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 17/165 (10%)

Query: 613 ALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE 672
           A D+VF+IDSSE +    F   ++FV  +V RL          +  RVGVVQ+S++  F 
Sbjct: 827 AADIVFLIDSSEGVRPDGFAHIRDFVSRIVRRLNI------GPSKVRVGVVQFSND-VFP 879

Query: 673 AIQLDDERIDSLSSFKEAVKNLEWIAGGTW-TPSALKFAYDRLIKESRRQKTR----VFA 727
              L   R  S +   +A++ L    G    T  AL+F    L  +S   +         
Sbjct: 880 EFYLKTYR--SQAPVLDAIRRLRLRGGSPLNTGKALEFVARNLFVKSAGSRIEDGVPQHL 937

Query: 728 VVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
           V++  G+     DD++  A   R   + ++G+GD   ++ E + +
Sbjct: 938 VLVLGGK---SQDDVSRFAQVIRSSGIVSLGVGDRNIDRTELQTI 979



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 25/167 (14%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSH----EGT 670
           D+VF++D S ++G  NF   ++F+  V+ RL  I +D       +V V QY+     E  
Sbjct: 38  DIVFLVDGSSALGLANFNAIRDFIAKVIQRL-EIGQDL-----IQVAVAQYADTVRPEFY 91

Query: 671 FEAIQLDDERIDSLSSFKEAVKNLEWIAGGT-WTPSALKFAYDRLIKESRRQKTR----V 725
           F       E I        AV+ ++ + G   +T SAL F  + L   S   +       
Sbjct: 92  FNTHPTKREVI-------TAVRKMKPLDGSALYTGSALDFVRNNLFTSSAGYRAAEGIPK 144

Query: 726 FAVVITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENL 772
             V+IT G+     D+++  A   +  ++ A  IG+   ++ E E +
Sbjct: 145 LLVLITGGK---SLDEISQPAQELKRSSIMAFAIGNKGADQAELEEI 188



 Score = 34.7 bits (78), Expect = 0.37
 Identities = 22/89 (24%), Positives = 50/89 (56%), Gaps = 3/89 (3%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYSHEGTFE 672
            +D+ F++DS+E+     F   K ++  +V +L  ++ DPK S+   RV VVQ++   + +
Sbjct: 2011 IDMAFILDSAETTTLFQFNEMKKYIAYLVRQLD-MSPDPKASQHFARVAVVQHAPSESVD 2069

Query: 673  AIQLDDERID-SLSSFKEAVKNLEWIAGG 700
               +   +++ SL+ +    K +++++ G
Sbjct: 2070 NASMPPVKVEFSLTDYGSKEKLVDFLSRG 2098



 Score = 30.8 bits (68), Expect = 5.4
 Identities = 34/132 (25%), Positives = 56/132 (42%), Gaps = 9/132 (6%)

Query: 612 GALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTF 671
           G  DVVF+ID S+S G   F   +  +  +V+ L     D   +T TRV V+Q+S +   
Sbjct: 623 GKRDVVFLIDGSQSAG-PEFQYVRTLIERLVDYL-----DVGFDT-TRVAVIQFSDDPKV 675

Query: 672 EAIQLDDERIDSLSSFKEAV--KNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVFAVV 729
           E +       D + +  + +  K    I  G       +  + R +     +    F V+
Sbjct: 676 EFLLNAHSSKDEVQNAVQRLRPKGGRQINVGNALEYVSRNIFKRPLGSRIEEGVPQFLVL 735

Query: 730 ITDGRHDPRDDD 741
           I+ G+ D   DD
Sbjct: 736 ISSGKSDDEVDD 747


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  317 bits (811), Expect = 4e-86
 Identities = 170/353 (48%), Positives = 198/353 (56%), Gaps = 22/353 (6%)

Query: 255 PGPSGPKGYRGQKGA---------KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF 305
           PGP+GP+G  G+ G          +G  G PG PG  G+ G PG +G  G PGP G  G 
Sbjct: 512 PGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGP 571

Query: 306 KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGE 365
           +G+ G  G  G KG  G  GKNG  G  G  G  GPPG  G+ G +GP G  G  G  G+
Sbjct: 572 RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGD 631

Query: 366 RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
            G  G +G  G PG  GPPGE G  G  G +G++GAPG+PG KG  G PG RGP   PG 
Sbjct: 632 TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGP---PGL 688

Query: 426 RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDR---GLPGPRGPQ----- 477
            G PG +G  G  GP+G KG  GP GP G AG  G +G  G+R   G PGP+G +     
Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGG 748

Query: 478 -GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGEPGPRGP 535
            GA G PGK G RG  G  GP G +GQPG KG+ G PG     GPRG+PGE+GE GP GP
Sbjct: 749 PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGP 808

Query: 536 EGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G  G  G  GEPG KGE+G P + G  G PG  GP G  GP G PGP G  G
Sbjct: 809 AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKG 861



 Score =  313 bits (801), Expect = 5e-85
 Identities = 177/372 (47%), Positives = 199/372 (53%), Gaps = 40/372 (10%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP---------IGFPGPKGVPG 304
           +PG  G +G  G  G  G+ G+PG PG +G  G PG  GP         +GFPGPKG  G
Sbjct: 529 VPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDG 588

Query: 305 FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY-------- 356
             G+ GE G  G  G  G  GKNG  G +G  G  GP G KGD G  GP G         
Sbjct: 589 APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGG 648

Query: 357 -PGEAGSPGERGDQ---------GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG 406
            PGE G PGE G +         GGKGD G PG RGPPG  GA    G +G +G PG  G
Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGA---PGLRGGAGPPGPEG 705

Query: 407 VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
            KGA G PGP G  G PG +G PG +G  GS GPKG+KG+PG  G  G+ G+ G +G  G
Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765

Query: 467 DRGLPGPRGPQGALGE---PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS----YPG 519
             G PGP G  G  GE   PG  G  G  G  G RG++G PGP G PG PG +      G
Sbjct: 766 PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG 825

Query: 520 PRGAPGEKGE---PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPG 576
            RGAPGEKGE   PG  GP GG G  G  G  G KGE+G P  PG  G PG RG  G PG
Sbjct: 826 ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPG 885

Query: 577 PEGEPGPPGDPG 588
             G PGPPG  G
Sbjct: 886 SNGNPGPPGPSG 897



 Score =  310 bits (794), Expect = 4e-84
 Identities = 171/386 (44%), Positives = 197/386 (51%), Gaps = 52/386 (13%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP+G  G  GQ G  G  GE G PG+KG  G PG+ GP G  GP G PG +G KGE G+
Sbjct: 806  PGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGS 865

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  GA G  G  G  G  G  G  GPPG  G PG  GP G  G  G+PG  G  G KGD
Sbjct: 866  PGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGD 925

Query: 375  PGRPGRR---------------------------GPPGEIGAKGS---KGYQGNSGAPGS 404
             G+PG +                           GPPG  G +GS   +G +G SG PG+
Sbjct: 926  AGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985

Query: 405  PGVKGAKGGPGPR------GPKGEPGRRGDPGTKGSPGSDGPKGEKGD------------ 446
             G+ G +G PGP+      G  GEPGR G+PG+ G PG DG  G KGD            
Sbjct: 986  NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045

Query: 447  ---PGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ 503
               PGP GP G AG+ G++G  G  G  G  GP G+ G PG QG RGD G+ G RG +G 
Sbjct: 1046 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 504  PGPKGDPGRPGF-SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP 562
             G +G PG PG    PGP G  G  G PGP GP G  G  G  G+ G  G  G    PGP
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGP 1165

Query: 563  PGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G  G RG  G PG  G+PGPPG PG
Sbjct: 1166 RGNRGERGSEGSPGHPGQPGPPGPPG 1191



 Score =  310 bits (793), Expect = 5e-84
 Identities = 175/382 (45%), Positives = 199/382 (52%), Gaps = 52/382 (13%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  GP G  G  G KG+ G  G  G+KG  G PG++G  G PG  G PG  G +G  G 
Sbjct: 248 PGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGE 307

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPG------CKGDPGNRG---PDGYPGEAGSPGE 365
            GR G PG AG  G DG +G  G+ GPPG        G PG +G   P G PG  G+PG+
Sbjct: 308 RGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ 367

Query: 366 RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
           RG+ G +G  G  G  GPPG  G+ G KG  G +G PG+PG+ GA+G PGP G  G PG 
Sbjct: 368 RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL 427

Query: 426 RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD------------RGLP-- 471
           RG  G    PG +G KGE   PGP G RG AG  G  GAKG+             GLP  
Sbjct: 428 RGGAG---EPGKNGAKGE---PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGA 481

Query: 472 ----------GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF------ 515
                     GP GP G  GE G  G RG PG AGPRG +G+PG  G PG PG       
Sbjct: 482 AGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGS 541

Query: 516 -------SYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGP 568
                    PGP G+ GE G PGP GP G RG  G+ G PG KG  G P   G  G PG 
Sbjct: 542 PGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG 601

Query: 569 RGPRGVPGPEGEPGPPGDPGLT 590
            GP+G PG  GE GP G PG T
Sbjct: 602 PGPQGPPGKNGETGPQGPPGPT 623



 Score =  309 bits (792), Expect = 6e-84
 Identities = 160/340 (47%), Positives = 187/340 (55%), Gaps = 10/340 (2%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           G  GP+G RG+ G  G  G  GE G+ G  G+PG  G  G  G +G PGF+G  G  G  
Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIP 500

Query: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375
           G KG  G  G  G  G +G  G  G  G  G PG RG  G PG  GS G+ G  G +G+ 
Sbjct: 501 GEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGES 560

Query: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
           GRPG  GP G  G  G  G+ G  G  G+PG  G +GGPG  GP+G PG+ G+ G +G P
Sbjct: 561 GRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPP 620

Query: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGD---P 492
           G  GP G+KGD GP GP+GL G  G  G  G+ G PG  GP+G  G PG  G +GD   P
Sbjct: 621 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680

Query: 493 GDAGPRGDSGQPGPKGDPGRP----GFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEP 548
           G+ GP G +G PG +G  G P    G    GP G PG  G PG +G  G RG     G P
Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL---GSP 737

Query: 549 GRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           G KG+KGEP  PG  G PG  GPRG  GP G PGP G PG
Sbjct: 738 GPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG 777



 Score =  303 bits (776), Expect = 4e-82
 Identities = 177/386 (45%), Positives = 203/386 (52%), Gaps = 55/386 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGF------PGPKGVPGFKGE 308
           PGP G  G+ G  GAKG +G  G PG  G  G  G  GP G       PGP G+ G  G 
Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394

Query: 309 KGEFGADGRKGAPGL---------AGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE 359
           KGE G  G  GAPGL         AG NG  G +G  G  G  G KG+PG RG  G  G 
Sbjct: 395 KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454

Query: 360 AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGA---KGGPGP 416
            G PG +G+ G  G PG PG  G PG  G +G+ G++G +G  G PG KG    +G PGP
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514

Query: 417 RGPKG---EPGR---------RGDPGTKGSPGSD---GPKGEKGD------PGPEGPRGL 455
            GP+G   EPGR         RG PG+ G PGSD   GP G +G+      PGP GPRG 
Sbjct: 515 AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQ 574

Query: 456 AGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP---KGDPGR 512
            G +G  G KG+ G PG  G +G  G PG QG  G  G+ GP+G  G  GP   KGD G 
Sbjct: 575 PGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634

Query: 513 PG----FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP---GE 565
           PG       PG  G PGE G+PG  GP   +GD G  G PG KG+ G P + GPP   G 
Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGP---KGDAGAPGAPGGKGDAGAPGERGPPGLAGA 691

Query: 566 PGPRGPRGVPGPE---GEPGPPGDPG 588
           PG RG  G PGPE   G  GPPG PG
Sbjct: 692 PGLRGGAGPPGPEGGKGAAGPPGPPG 717



 Score =  303 bits (776), Expect = 4e-82
 Identities = 166/368 (45%), Positives = 192/368 (52%), Gaps = 34/368 (9%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  G  G RG  G+ G  G+ GEPG  G  G PG +GP G  GP G PG  G+ G+ G 
Sbjct: 722  PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G PG+AG  G+ G++G+ G  GP G  G PG  G  G  GE G+PGE+G+ G  G 
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGS---------PGVKGAKGGPGPRGPKGEPGR 425
             G PG  GP G  G +G KG +G+ G PG+         PG  G+ G PGP GP G PG+
Sbjct: 842  AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901

Query: 426  RGDP------GTKGSPGSDGPK------GEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGP 473
             G P      G  GSPG  GPK      GEKG PG +GP G  G +G  G  G RGL GP
Sbjct: 902  DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGP 961

Query: 474  RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS----YPGPRGAPGEKGE 529
             G  G  G PG QG +G+ G  G  G SG+ GP G  G PG +     PG  G PG  G 
Sbjct: 962  PGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGL 1021

Query: 530  PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP---------PGEPGPRGPRGVPGPEGE 580
            PG  G  GG+GD G  G PG  G  G P  PGP          GE GP GP G PGP G 
Sbjct: 1022 PGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081

Query: 581  PGPPGDPG 588
             G PG  G
Sbjct: 1082 RGAPGPQG 1089



 Score =  297 bits (760), Expect = 3e-80
 Identities = 168/398 (42%), Positives = 200/398 (50%), Gaps = 64/398 (16%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP+GP G  G  G  G+ G PG PG +G  G+PG  GP G PGP G  G  G  G+ G 
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGE 232

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            GR G PG  G  G  G KG  G  G PG KG  G  G +G  GE G+PG +G+ G  G+
Sbjct: 233 SGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGE 292

Query: 375 PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP------KGEPGRRGD 428
            G PG  GP G  G +G  G  G +GA G+ G +G+ G PGP GP       G PG +G+
Sbjct: 293 NGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGE 352

Query: 429 PGTKGSPGSDGPKGEKGDPGPE---------GPRGLAGEVGNKGAKGDRGLP-------- 471
            G  GSPGS+G  G++G+PGP+         GP G+ G  G KG  G  G+P        
Sbjct: 353 VGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGA 412

Query: 472 -GPRGPQGA---------LGEPGKQGSRGDPGDAGPRGD--------------------- 500
            GP GP GA          GEPGK G++G+PG  G RG+                     
Sbjct: 413 RGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGE 472

Query: 501 ---SGQPGPKGDPGRPGFSYP-GPRGAPGEK------GEPGPRGPEGGRGDFGLKGEPGR 550
              +G PG  G+ G PGF  P GP G PGEK      G PGP GP G  G+ G  G PG 
Sbjct: 473 PGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGG 532

Query: 551 KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G +G P  PG PG  G  GP G  G  G PGPPG  G
Sbjct: 533 PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG 570



 Score =  295 bits (754), Expect = 2e-79
 Identities = 159/344 (46%), Positives = 181/344 (52%), Gaps = 10/344 (2%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  GP G  G  G +G  G PG  G KG  G PG  G  G PG +G+PG +G  G  G 
Sbjct: 680  PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739

Query: 315  DGRKGAPGLAGKNGT---DGQKGKLGRIGPPGCKGDPGNRGPDGYPG------EAGSPGE 365
             G KG PG  G +G    DG +G  G IGPPG  G PG++G  G PG        GSPGE
Sbjct: 740  KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 366  RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
            RG+ G  G  G PG  G  GE G KG +G  G  G  G PGV G  GG GP GP G  G 
Sbjct: 800  RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 426  RGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK 485
            +G+ G+ G PG+ G  G +G PGP G  G  G  G  G+ G  G PGP G  GA G PG 
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919

Query: 486  QGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS-YPGPRGAPGEKGEPGPRGPEGGRGDFGL 544
             G +GD G  G +G  G  GP G PG  G +   G RG  G  G PGPRG  G +G  G 
Sbjct: 920  SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE 979

Query: 545  KGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G+PG  G  GE   PGP G PG  G  G PG +G PG  G PG
Sbjct: 980  SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023



 Score =  292 bits (747), Expect = 1e-78
 Identities = 172/381 (45%), Positives = 200/381 (52%), Gaps = 46/381 (12%)

Query: 255  PGPSGPKGYRGQ------KGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PGP+GP G +G       +G +G  G  G PG+ G+ G+PG +G  G PG  G  G  G 
Sbjct: 620  PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679

Query: 309  KGEFGADGRKGAPGL---AGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGE 365
             GE G  G  GAPGL   AG  G +G KG  G  GPPG  G PG +G  G  G  GSPG 
Sbjct: 680  PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739

Query: 366  RGDQGGKGDPG------RPGRRGPPGEIGAKGSKGY---QGNSGAPGSPGVKGAKGGPGP 416
            +GD+G  G PG      + G RGP G IG  G  G    +G  GAPG PG+ G +G PG 
Sbjct: 740  KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 417  RGPKGEPG---------RRGDPGTKGSPGSDGPKGEKGDP---GPEGPRGLAGEVGNKGA 464
            RG  G PG         + G+PG KG  G+ G KGE G P   GP G  G AG  G +G 
Sbjct: 800  RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 465  KGDRGLPGPRGP---QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD------PGRPGF 515
            KG+RG PG  G     GA G PG  GS G+PG  GP G  G+ GP G       PG PG 
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919

Query: 516  SYP-GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGV 574
            S P G  G PGEKG PG +GP G  G  G+ G  G +G  G P  PGP G PGP+G +G 
Sbjct: 920  SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE 979

Query: 575  PGP------EGEPGPPGDPGL 589
             G        GE GPPG  GL
Sbjct: 980  SGKPGANGLSGERGPPGPQGL 1000



 Score =  287 bits (734), Expect = 3e-77
 Identities = 161/342 (47%), Positives = 177/342 (51%), Gaps = 17/342 (4%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
            GP GP G  GQ G KG  G PG PG  G +G PG  G  G PGP G PG  G+ GE G  
Sbjct: 765  GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGK 824

Query: 316  GRKGAPGLAGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372
            G +GAPG  G+ G  G  G     G  GPPG +G  G RG  G PG AG PG RG  G  
Sbjct: 825  GERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP 884

Query: 373  GDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTK 432
            G  G PG  GP G  G  G  G  GN+GAPGSPGV G KG  G  G KG PG +G PG  
Sbjct: 885  GSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944

Query: 433  GS---PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQ 486
            G     G  G +G  G PG  GPRG  G  G KG  G     GL G RGP G  G PG  
Sbjct: 945  GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA 1004

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKG 546
            G+ G+PG  G  G  G PG  G PG  G    G  G+PG  G PG  GP G        G
Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGDR--GENGSPGAPGAPGHPGPPGP------VG 1056

Query: 547  EPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
              G+ G++GE    GP G PGP G RG PGP+G  G  G+ G
Sbjct: 1057 PAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETG 1098



 Score =  277 bits (708), Expect = 3e-74
 Identities = 164/396 (41%), Positives = 187/396 (47%), Gaps = 55/396 (13%)

Query: 243 YGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDP-------------- 288
           +GEC  V       P+ P   +G +G KG+ G PG PG+ G  G P              
Sbjct: 81  FGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI 140

Query: 289 ------------------------------GIEGPIGFPGPKGVPGFKGEKGEFGADGRK 318
                                         G  GP G PGP G PG  G  G  G+ G +
Sbjct: 141 CESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQ 200

Query: 319 GAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRP 378
           G PG  G+ G  G  G  G IGP G  G  G  G  G PGE G PG  G +G  G PG P
Sbjct: 201 GPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFP 260

Query: 379 GRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD---PGTKGSP 435
           G +G  G  G  G KG  G  G  G  G+ G  G PGP GP+G PG RG    PG  G+ 
Sbjct: 261 GMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGAR 320

Query: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQGSRGDP 492
           G+DG +G  G PGP GP G AG  G+ GAKG+    G PG  G  G  GEPG QG  G  
Sbjct: 321 GNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380

Query: 493 GDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKG 552
           G  GP G +G PG KG+ G  G   PG  G  G +G PGP G  G  G  G  GEPG+ G
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGI--PGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 553 EKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            KGE   PGP GE G  G  GVPG +GE G  G PG
Sbjct: 439 AKGE---PGPRGERGEAGIPGVPGAKGEDGKDGSPG 471



 Score =  248 bits (633), Expect = 2e-65
 Identities = 143/309 (46%), Positives = 165/309 (53%), Gaps = 25/309 (8%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEG------PIGFPGPKGVPGFKGE 308
            PG SGPKG  GQ G KG+ G  G PG  G  G  GI G      P G PGP+G PG +G 
Sbjct: 917  PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP---GE 365
            KGE    G+ GA GL+G+ G  G +G  G  G  G  G  GN G DG PG  GSP   G+
Sbjct: 977  KGE---SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033

Query: 366  RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNS---GAPGSPGVKGAKGGPGPRGPKGE 422
            RG+ G  G PG PG  GPPG +G  G  G +G S   G  G+PG  G++G PGP+GP   
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGP--- 1090

Query: 423  PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482
               RGD G  G  G+ G KG +G PG  G  G  G  G +GA G  G  GPRGP G  G 
Sbjct: 1091 ---RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 483  PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDF 542
            PGK G+ G PG  GP G  G  G +G  G PG  +PG  G PG  G PGP    GG G  
Sbjct: 1148 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG--HPGQPGPPGPPGAPGPCC--GGVGAA 1203

Query: 543  GLKGEPGRK 551
             + G  G K
Sbjct: 1204 AIAGIGGEK 1212



 Score =  186 bits (472), Expect = 8e-47
 Identities = 111/241 (46%), Positives = 127/241 (52%), Gaps = 27/241 (11%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            GE  K     + G  GP G +G  G  G  GEP      GR G+PG +   G PG  G P
Sbjct: 978  GESGKPGANGLSGERGPPGPQGLPGLAGTAGEP------GRDGNPGSD---GLPGRDGSP 1028

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
            G KG++GE G+ G  GAPG  G  G  G  GK       G +G+ G  GP G PG AGS 
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGK------SGDRGESGPAGPAGAPGPAGSR 1082

Query: 364  GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP---GVKGAKGGPGPRGPK 420
            G  G QG +GD G  G R   G  G KG +G+ GN GAPGSP   G +GA G PGP GP 
Sbjct: 1083 GAPGPQGPRGDKGETGER---GAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP- 1138

Query: 421  GEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
                 RG  G  G PG DG  G  G  GP GPRG  GE G++G+ G  G PGP GP GA 
Sbjct: 1139 -----RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193

Query: 481  G 481
            G
Sbjct: 1194 G 1194



 Score =  138 bits (348), Expect = 2e-32
 Identities = 86/202 (42%), Positives = 97/202 (48%), Gaps = 31/202 (15%)

Query: 402 PGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKG--DPGPEGPRGLAGEV 459
           P   G +G KG PGP    G PGR GDPG  G PGS G  G  G  +  P GP+  + + 
Sbjct: 99  PNGQGPQGPKGDPGP---PGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQY 155

Query: 460 GNKGAK------GDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRP 513
            +   K      G  G PGP GP G  G PG  G  G PG          PG +G PG P
Sbjct: 156 DSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGS---------PGYQGPPGEP 206

Query: 514 GFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADP------GPPGEPG 567
           G +  GP G PG  G  GP GP G  G+    G PGR GE+G P  P      G PG PG
Sbjct: 207 GQA--GPSGPPGPPGAIGPSGPAGKDGE---SGRPGRPGERGLPGPPGIKGPAGIPGFPG 261

Query: 568 PRGPRGVPGPEGEPGPPGDPGL 589
            +G RG  G  GE G  G PGL
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGL 283



 Score = 56.6 bits (135), Expect = 9e-08
 Identities = 23/44 (52%), Positives = 27/44 (61%)

Query: 548 PGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTE 591
           P  +G +G   DPGPPG PG  G  G+PG  G PG PG PG+ E
Sbjct: 99  PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICE 142


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  313 bits (801), Expect = 5e-85
 Identities = 175/391 (44%), Positives = 206/391 (52%), Gaps = 54/391 (13%)

Query: 250 SCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
           +C E+P    P     ++G  G  G PG PG  G  G  GI+G  G  GP G PG  GE 
Sbjct: 251 TCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP 310

Query: 310 GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNR--------GPDGYPGEAG 361
           G+ GA G+ G PG  G  G DG  G +G  G  G  G PG+R        GP G PG AG
Sbjct: 311 GKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAG 370

Query: 362 SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQ------------GNSGAPGSPGVKG 409
            PGE G  G  GDPGR G  GPPG  G +G+ G+             G SG PG PG++G
Sbjct: 371 LPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRG 430

Query: 410 AKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRG 469
            KG    +G  GEPGR+G  G +G  G  G  G +G PG +G RG+ G VG+KG KG RG
Sbjct: 431 HKGA---KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 487

Query: 470 LPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ---------PGPKGDPGRPGF----S 516
           L G  GPQG  G PG QG RG PG+AGP+GD G          PGPKGD G PG      
Sbjct: 488 LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 547

Query: 517 YPGPRGAPGEKGEPGP------------------RGPEGGRGDFGLKGEPGRKGEKGEPA 558
            PG  G  GE G+PGP                  +G  G +G  G  G+PG+ G  G+P 
Sbjct: 548 IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 607

Query: 559 DPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
             GPPGE GPRGP+G+PG  GE GP G PGL
Sbjct: 608 QQGPPGEVGPRGPQGLPGSRGELGPVGSPGL 638



 Score =  288 bits (736), Expect = 2e-77
 Identities = 168/381 (44%), Positives = 195/381 (51%), Gaps = 47/381 (12%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP---IGF------------PG 298
           IPGP GP G  G  G  G +G  G+PG++G  G PG  GP   IGF            PG
Sbjct: 359 IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPG 418

Query: 299 PKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIG---PPGC----------- 344
             G PG  G +G  GA G  G PG  G  G +G +G+LG +G   PPG            
Sbjct: 419 RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVG 478

Query: 345 -KGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403
            KG+ G RG DG PG  G PG  GDQG +G PG  G +G  G  GA+G  G  G  G  G
Sbjct: 479 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 538

Query: 404 SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS------PGSDGPKGEKGDPGPEGPRGLAG 457
            PGV G  G PG  G KGEPG+ G PG  G       PG  G KG  G+ G  G  G  G
Sbjct: 539 LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG 598

Query: 458 EVGNKGAKGDRGLPG---PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG 514
           ++GN G  G +G PG   PRGPQG  G  G+ G  G PG  G  G  G PG  G PG PG
Sbjct: 599 QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG 658

Query: 515 FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE------KGEPADPGPPGEPGP 568
              PG +G  G  GEPGP+G +G  G+ G  GE G  G+      KG   +PG PG  GP
Sbjct: 659 L--PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 716

Query: 569 RGPRGVPGPEGEPGPPGDPGL 589
            G RG+PG EG  GPPG  G+
Sbjct: 717 EGSRGLPGVEGPRGPPGPRGV 737



 Score =  283 bits (725), Expect = 4e-76
 Identities = 161/357 (45%), Positives = 186/357 (52%), Gaps = 21/357 (5%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF---------K 306
           G  G  G RG KGAKG +GEPG  G KG +GD G  G +G  GP G  G          K
Sbjct: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 480

Query: 307 GEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGER 366
           GEKG  G DG  G  GL G  G  GQ+G  G  GP G +G  G RG  G PG  G  G  
Sbjct: 481 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 540

Query: 367 GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
           G  G  G PG PG +G PG+ G  G  G QG    PG PG+ GAKG  G +G  G PG+ 
Sbjct: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG---LPGVPGIPGAKGVAGEKGSTGAPGKP 597

Query: 427 GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQ 486
           G  G  G PG  GP GE G   P GP+GL G  G  G  G  GLPG  G  G+ G PG  
Sbjct: 598 GQMGNSGKPGQQGPPGEVG---PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 654

Query: 487 GSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLK 545
           G  G PG  G RG  G+PGPKG+ G  G     G RG  G+ G PGP+G  G  G+ GL+
Sbjct: 655 GPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR 714

Query: 546 GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETC 602
           G    +G +G P   GP G PGPRG +G  G  G PG  G PG    D   ++++ C
Sbjct: 715 GP---EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTD--QHIKQVC 766



 Score =  282 bits (721), Expect = 1e-75
 Identities = 169/393 (43%), Positives = 195/393 (49%), Gaps = 56/393 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG +GPKG RG +GA+G  G PG  G  G  G  G +G  G PG KG PG  G  G+ G 
Sbjct: 510 PGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL 569

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            G  G PG+ G  G  G+KG  G  G PG  G+ G  G  G PGE G  G +G  G +G+
Sbjct: 570 QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629

Query: 375 PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
            G  G  G PG++G+ GS G  G  G PG PG+KG +G  G  GPKGE G  G+ G  G 
Sbjct: 630 LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE 689

Query: 435 PGS------DGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
            G        GPKG  G+PG  G RG  G  G  G +G RG PGPRG QG  G  G  G 
Sbjct: 690 RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 749

Query: 489 RGDPG------------------------------DAGPRGDSGQPGPKGDPGRPGFS-Y 517
           +G PG                              D+G  G  G+PGP G PG PG + +
Sbjct: 750 QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809

Query: 518 PGP---RGAPGEKGEPGPRGPEGGRGDFGLKGE---PGR-----KGEKGEPADPGPP--- 563
           PG    RG PG KG PG  G  G +GD G KGE   PGR      G  G P DPGP    
Sbjct: 810 PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYG 869

Query: 564 -----GEPGPRGPRGVPGPEGEPGPPGDPGLTE 591
                GE GP G  G+PG  G PGPPG PG  E
Sbjct: 870 RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 902



 Score =  276 bits (705), Expect = 7e-74
 Identities = 176/422 (41%), Positives = 208/422 (49%), Gaps = 86/422 (20%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGPKGVPGFKGEKG 310
           I G  G KG RG  G  G  G PG PG +G++G PG  GP G     G +G+PG  G KG
Sbjct: 476 IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKG 535

Query: 311 EFG---ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERG 367
           + G    DGR G PG+ G  G  G+ G  G  G  G  G PG  G  G  GE GS G  G
Sbjct: 536 DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG 595

Query: 368 DQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSG------APGSPGVKGAKGGPGPRG--- 418
             G  G+ G+PG++GPPGE+G +G +G  G+ G      +PG PG  G+ G PG  G   
Sbjct: 596 KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 655

Query: 419 PKGEPGRRGD------PGTKGSPGSDGPKGEKGD---------PGPEGPRGLAGEVGNKG 463
           P G PG +GD      PG KG  G+ G +GE G+         PGP+G  G  GE G +G
Sbjct: 656 PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 715

Query: 464 AKGDRGLP---GPRGPQGALGEPGKQGSRGDPG--------------------------- 493
            +G RGLP   GPRGP G  G  G+QG+ G PG                           
Sbjct: 716 PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA 775

Query: 494 ---------DAGPRGDSGQPGPKGDPGRPGFS-YPGP---RGAPGEKGEPGPRGPEGGRG 540
                    D+G  G  G+PGP G PG PG + +PG    RG PG KG PG  G  G +G
Sbjct: 776 EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 835

Query: 541 DFGLKGE---PGR-----KGEKGEPADPGPP-----GEPGPRGPRGVPGPEGEPGPPGDP 587
           D G KGE   PGR      G  G P DPGP      G  G RGP GV G  G PGPPG P
Sbjct: 836 DLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895

Query: 588 GL 589
           GL
Sbjct: 896 GL 897



 Score =  270 bits (690), Expect = 4e-72
 Identities = 169/432 (39%), Positives = 202/432 (46%), Gaps = 99/432 (22%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF---KGEKG 310
           +PG  G  G RG KG  G  G  GEPG+ G  G PG  G  G  GP G PG    KG+KG
Sbjct: 285 VPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKG 344

Query: 311 EFGADGRKGAPGLA-----GKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS--- 362
           E G  G +G PG       G  GT G  G+LGR+GP G   DPG RGP G PG  G    
Sbjct: 345 EPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVG---DPGRRGPPGPPGPPGPRGT 401

Query: 363 ------------------------PGERGDQGGKGDPGRPGRRG---------------- 382
                                   PG RG +G KG+ G PGR+G                
Sbjct: 402 IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461

Query: 383 --PPGEIGAKG------SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR------RGD 428
             PPG  G +G       KG +G  G  G PG +G  G PG +G +G PG       RG 
Sbjct: 462 QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 521

Query: 429 PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
            G +G PG  GPKG+ G PG +G  G+ G  G KG  G  G PG  G QG  G PG  G+
Sbjct: 522 EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA 581

Query: 489 RGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-------GPRGAPGEKGE------------ 529
           +G  G+ G  G  G+PG  G+ G+PG   P       GP+G PG +GE            
Sbjct: 582 KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 641

Query: 530 ------------PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGP 577
                       PGP G  G +GD G+ GEPG KGE+G   + G  GE G  G  G+PGP
Sbjct: 642 LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701

Query: 578 EGEPGPPGDPGL 589
           +G  G PG+PGL
Sbjct: 702 KGSAGNPGEPGL 713



 Score =  245 bits (625), Expect = 1e-64
 Identities = 145/346 (41%), Positives = 168/346 (48%), Gaps = 50/346 (14%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           +PG  G  G +G  G KG+ G PG+PGQ G  G PG +GP G  GP+G  G  G +GE G
Sbjct: 572 LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELG 631

Query: 314 ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
             G  G PG  G  G+ G  G  G  G PG KGD G  G  G  GE G+ GE G+ G +G
Sbjct: 632 PVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERG 691

Query: 374 DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
           + G  G  GP G  G  G  G +G  G+ G PGV+G +G PGPRG +GE G  G PG +G
Sbjct: 692 ELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQG 751

Query: 434 SPG------------------------------SDGPKGEKGDPGPEGPRGLAGEVGNKG 463
            PG                                G  G  G PGP GP G  GE G  G
Sbjct: 752 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 811

Query: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP--RGDSGQPGPKGDPGRPGFSYPGPR 521
             G RGLPG +GP GALG  G +G  G+ G+ GP  RG +G PG  G PG PG   P   
Sbjct: 812 QMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG---PASY 868

Query: 522 GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPG 567
           G  G  GE GP               PG  G  G P  PGPPG PG
Sbjct: 869 GRNGRDGERGP---------------PGVAGIPGVPGPPGPPGLPG 899



 Score =  176 bits (446), Expect = 8e-44
 Identities = 115/311 (36%), Positives = 134/311 (43%), Gaps = 65/311 (20%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G +G  G +G PG PG+ G  G PG+ G    PGP G+PG KG++G  G  
Sbjct: 616 GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEP 672

Query: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------------------------- 350
           G KG  G +G+ G  G++G+LG IG PG KG  GN                         
Sbjct: 673 GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPP 732

Query: 351 --RGPDGYPGEAGSPGERG---------------------------------DQGGKGDP 375
             RG  G  G  G PG +G                                 D G  G P
Sbjct: 733 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792

Query: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
           GRPG  GPPG  G  G  G  G  G PG  G  GA G  GP+G  GE G RG PG +G  
Sbjct: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPN 851

Query: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
           G  G  G  GDPGP    G  G  G +G  G  G+PG  GP G  G PG          A
Sbjct: 852 GLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA 910

Query: 496 GPRGDSGQPGP 506
           G R  +  P P
Sbjct: 911 GQRAFNKGPDP 921



 Score =  134 bits (337), Expect = 3e-31
 Identities = 87/237 (36%), Positives = 104/237 (43%), Gaps = 29/237 (12%)

Query: 244 GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
           GE  ++  + +PGP G  G  G+ G +G  G  G PG +G +G PG  G  G  G  G+P
Sbjct: 688 GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 747

Query: 304 GFKGEKGEFGADGR--------------KGAPGL----AGKNGTDGQKGKLGRIGPPGCK 345
           G +G  G    D                + A  L    +G  G  G+ G  G  GPPG  
Sbjct: 748 GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN 807

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
           G PG  G  G PG  G PG  G +G KGD G  G RGPPG    +G  G  G  G PG P
Sbjct: 808 GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDP 863

Query: 406 GVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
                  GP   G  G  G RG PG  G PG  GP G  G PG   P     + G +
Sbjct: 864 -------GPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913



 Score =  124 bits (311), Expect = 4e-28
 Identities = 76/158 (48%), Positives = 84/158 (53%), Gaps = 21/158 (13%)

Query: 439 GPKGEKGDPGPEGPRGLAGEVG---NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
           GP GE+G PGP GP G+ G  G   ++G KG  G PGP G  G  G PGK G+ G  G  
Sbjct: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328

Query: 496 GPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555
           GP G  G  G KG  G PG   PG RG PG +G PGP GP G  G   L GE GR G   
Sbjct: 329 GPDGSPGSIGSKGQKGEPGV--PGSRGFPG-RGIPGPPGPPGTAG---LPGELGRVG--- 379

Query: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
                 P G+PG RGP   PGP G PGP G  G  + D
Sbjct: 380 ------PVGDPGRRGP---PGPPGPPGPRGTIGFHDGD 408



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 37/73 (50%), Positives = 41/73 (56%), Gaps = 9/73 (12%)

Query: 521 RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
           RG PGE+G PGP GP G  G  G+ G+ G KG         PPG PGP G  G PG  G+
Sbjct: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKG---------PPGPPGPAGEPGKPGAPGK 318

Query: 581 PGPPGDPGLTECD 593
           PG PG  GLT  D
Sbjct: 319 PGTPGADGLTGPD 331



 Score = 38.1 bits (87), Expect = 0.034
 Identities = 18/37 (48%), Positives = 19/37 (51%)

Query: 557 PADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           PA   P      RGP G  GP G PGPPG PG+   D
Sbjct: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGID 292


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  311 bits (798), Expect = 1e-84
 Identities = 174/395 (44%), Positives = 202/395 (51%), Gaps = 61/395 (15%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
            GP GP G  G  G +G+ G+ G PG KG +GD G  GP G PG +G  G  G  G  GA 
Sbjct: 1061 GPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQ 1120

Query: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG---------------------DPGNRGPD 354
            GR+G PGL G+ G DG +G +G IGPPG +G                      PG RGP 
Sbjct: 1121 GRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQ 1180

Query: 355  G---------------YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNS 399
            G                PG  G  GERGD G  G PG PG  GP G+IG KG  G  G +
Sbjct: 1181 GPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAA 1240

Query: 400  GAPGS---PGVKGAKGGPGPRGPKGE---------------PGRRGDPGTKGSPGSDGPK 441
            G PG    PG  GAKG  GP G  G+               PG +GDPG  G PG  G  
Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGAS 1300

Query: 442  GEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS 501
            GE G PGP G RG +G +G +G +G++G  G  GP G  G  G  G+RG PG  GP G  
Sbjct: 1301 GEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR 1360

Query: 502  GQPGPKGDP---GRPGFSYP----GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554
            G PGP G+P   G PG   P    GP G PG KG+ GP+G +G  G  GL G PG  GEK
Sbjct: 1361 GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEK 1420

Query: 555  GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
            G+   PG  G PGP+G  G PGP G  G PG PG+
Sbjct: 1421 GDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGV 1455



 Score =  305 bits (782), Expect = 9e-83
 Identities = 171/357 (47%), Positives = 195/357 (54%), Gaps = 29/357 (8%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PG SG +G  G  G KG+ GE G PG  G+ G PG  GP+G PG  G  G +G+KG+ G
Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVG 1082

Query: 314  ADGRKGAPGLAGKNGTDGQ---KGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQG 370
            A G KG+ G  G  G  GQ   +G  G  GPPG  G  G RGP G  G+ G  G RG  G
Sbjct: 1083 APGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVG 1142

Query: 371  GKGDPGRPGRRGPPGE------------IGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG 418
              G PG  G  GPPGE             GA G +G QG +G+ G+PG+ G  G PG  G
Sbjct: 1143 VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVG 1202

Query: 419  PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQG 478
             KGE G  GDPG  G+PG  GPKG+ G+ G  GP G AG  G KG       PG  G +G
Sbjct: 1203 EKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGP------PGEDGAKG 1256

Query: 479  ALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG 538
            ++G  G  G  G PGD G  G  G PG KGDPG  G   PGP GA GE G PGP G  G 
Sbjct: 1257 SVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG--GPGPPGASGEPGAPGPPGKRGP 1314

Query: 539  RGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVP---GPE---GEPGPPGDPGL 589
             G  G +G  G KG KGEP   GPPG  GP G RG P   GPE   G PGP G+PGL
Sbjct: 1315 SGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL 1371



 Score =  301 bits (772), Expect = 1e-81
 Identities = 166/346 (47%), Positives = 191/346 (55%), Gaps = 13/346 (3%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           +PGP G  G  G+KG  GN G PG PG  G  G PG EGP G  G +G PG  G  G   
Sbjct: 651 LPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGY-- 708

Query: 314 ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
             G +G  G +G  G  G+KG+ G  G PG KGD G +G  G PG  G  GE G +G KG
Sbjct: 709 -PGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG 767

Query: 374 DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP---KGEPGRRGDPG 430
             G+ G  GPPG  G KG  G  G  G PG PG KG+ G PGP GP   KG+ G+ G PG
Sbjct: 768 QAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPG 827

Query: 431 TKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGA---KGDRGLPGPRGP---QGALGEPG 484
            +G  G  G +GE+G PG  G  G  G+VG  GA    G++GLPG +GP    G  G PG
Sbjct: 828 LEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887

Query: 485 KQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-GPRGAPGEKGEPGPRGPEGGRGDFG 543
            QG  G PG  G RG+ G  G  G PG  G   P G  G  G  GE GP GP G  G+ G
Sbjct: 888 HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947

Query: 544 LKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGL 589
           L G  GR+G KGE   PGP G+ GP G RG PGP+G PG PG  GL
Sbjct: 948 LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993



 Score =  299 bits (765), Expect = 8e-81
 Identities = 179/429 (41%), Positives = 207/429 (48%), Gaps = 94/429 (21%)

Query: 255  PGPSGPKGY---RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
            PG +GP GY   RG KG  GN G  GE G+KG  G PG +G +G  G +G PG  G +GE
Sbjct: 700  PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG---YPGEAGSPGERGD 368
             G +G KG  G AG+ G  G  G+ G++G PG  G PG  GP G   +PG  G  GE+G 
Sbjct: 760  DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819

Query: 369  QGGKGDPGRPGRRGPPGEIGAKGS---------KGYQGNSGAPGSPGVKGA---KGGPGP 416
             G  G PG  G RGPPG  G +G          KG  G  GAPG PG KG    +G PG 
Sbjct: 820  SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879

Query: 417  RGPKGEPGRRGDPGTKGSPGSDG---------------------------PKGEKGDPGP 449
             GPKG PG +G  G  G PG  G                           P GE+G PGP
Sbjct: 880  PGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGP 939

Query: 450  EGP---RGLAGEVGNKGAKGDRGLPGP---RGPQGALGEPGKQGSRGDPGDAGPRGDSGQ 503
             GP   +GL G  G +GAKG+ G PGP    GP G  G PG +G  GDPG  G +GD G 
Sbjct: 940  PGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGP 999

Query: 504  PGPKGDPGRPGFSYP----------------------GPRGAPGEKGEPGP--------- 532
            PGP G  G PG   P                      G +G+ GE+G PGP         
Sbjct: 1000 PGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGP 1059

Query: 533  ---------RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGP---EGE 580
                      GP G  GD G  G PG KG KG+  D GPPG+PG RGP G PGP   +G 
Sbjct: 1060 LGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGA 1119

Query: 581  PGPPGDPGL 589
             G  G PGL
Sbjct: 1120 QGRRGPPGL 1128



 Score =  298 bits (763), Expect = 1e-80
 Identities = 172/377 (45%), Positives = 199/377 (52%), Gaps = 43/377 (11%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  G  G  G++GAKG +G PG  G++G  G  G  GP G PG  G  G KG+KG  G 
Sbjct: 943  PGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGP 1002

Query: 315  DGRKGAPGL------AGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
             G  G+PG       AG  G  GQ G  G +GP G KG  G RGP G  G+ G PG  G 
Sbjct: 1003 VGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGP 1062

Query: 369  QGGKGDPGRPGRRGPPGEIGA---KGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR 425
             G  G  G  G  G  G++GA   KGSKG +G++G PG PG++G  G PGP G  G  GR
Sbjct: 1063 LGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGR 1122

Query: 426  RGDPGTKGSPGSDGPKGEKGDPGP------EGPRGLAGEVGNKGAKGDRGLPGPRGPQ-- 477
            RG PG  G  G DG +G  G  GP       GP G  GEVG+ G+ G  G PGPRGPQ  
Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182

Query: 478  ----------GALGEP---GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS-------Y 517
                      G +G+P   G++G RGD GD GP G  G PGPKGD G  G S        
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGP 1242

Query: 518  PGPRGAPGEKGEPGPRGPEGGRGDFGLKGEP------GRKGEKGEPADPGPPGEPGPRGP 571
            PG +G PGE G  G  GP G  GD G  G+P      G  GEKG+P D G PG PG  G 
Sbjct: 1243 PGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGE 1302

Query: 572  RGVPGPEGEPGPPGDPG 588
             G PGP G+ GP G  G
Sbjct: 1303 PGAPGPPGKRGPSGHMG 1319



 Score =  297 bits (760), Expect = 3e-80
 Identities = 161/340 (47%), Positives = 186/340 (54%), Gaps = 17/340 (5%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PGP G  G RG +G  G  G+ GEPG +G  G  G  GP G PG  G+ G  G KG  G 
Sbjct: 574 PGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGP 633

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGE---AGSPGERGDQGG 371
            G  G PG  G +G+ G  G  G IG PG KG PGN G  G PG     G PG  G  G 
Sbjct: 634 PGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGE 693

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP---KGEPGRRGD 428
           KG  G PG  GPPG  G +G KG  GN G  G  G KG  G PG +G    KG+ G+ G 
Sbjct: 694 KGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGA 753

Query: 429 PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
           PG +G  G +GPKG+ G  G EGP G AGE G  G  G  G PG  GP+G++G PG  G 
Sbjct: 754 PGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGP 813

Query: 489 RGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEP 548
            G+ G +G    +GQPG +G+ G PG    G RG PG  G+PGP      +GD G  G P
Sbjct: 814 IGEKGKSGK---TGQPGLEGERGPPGSR--GERGQPGATGQPGP------KGDVGQDGAP 862

Query: 549 GRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           G  GEKG P   GPPG PGP+GP G  G +G PG PG  G
Sbjct: 863 GIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRG 902



 Score =  291 bits (746), Expect = 1e-78
 Identities = 165/365 (45%), Positives = 197/365 (53%), Gaps = 38/365 (10%)

Query: 252 LEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           L + GP GP G  G+ G    +G PG PG KG +G  G +GP G  GP G PG  G+ G 
Sbjct: 475 LSMKGPPGPVGLTGRPGP---VGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGR 531

Query: 312 FGADGRKGAPG------------LAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPG- 358
            GADG +G PG            L G  G  GQ+G  G +G PG  G+ G RG +G PG 
Sbjct: 532 PGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP 591

Query: 359 --EAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKG---AKGG 413
             +AG PG RG  G +G PG  GR G  G  GA G+KG  G  G PG PG +G   ++G 
Sbjct: 592 TGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGL 651

Query: 414 PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGP 473
           PGP+G  G PG +G PG  G PG  G  G  G PG EGP G  G  G  G+ G  G PGP
Sbjct: 652 PGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGP 711

Query: 474 RGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPR 533
           RG +G  G  G QG +G+ G+ G  G  G  G KGD G+P        GAPG +GE GP 
Sbjct: 712 RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP--------GAPGPRGEDGPE 763

Query: 534 GPEGGRGDFGLKGEPGRKGEKGE---PADPGPPGEPGPRGPRGVPGP------EGEPGPP 584
           GP+G  G  G +G PG  GEKG+   P  PG PG PGP+G  G PGP      +G+ G  
Sbjct: 764 GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKT 823

Query: 585 GDPGL 589
           G PGL
Sbjct: 824 GQPGL 828



 Score =  288 bits (738), Expect = 1e-77
 Identities = 168/390 (43%), Positives = 199/390 (51%), Gaps = 59/390 (15%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV------PGFKGE 308
            PG  GP G+ G  GA G  G  G PG  G++GD G+ G +G  GP G+      PG KGE
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161

Query: 309  KGEFGADGRKGAPGLAGKNG---TDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPG- 364
             G+ G+ G  GAPG  G  G   ++G  G  G +G PG  G+ G RG  G PG  G+PG 
Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221

Query: 365  --------ERGDQGGKGDPGRPGRRGPPGEIGAKGS---KGYQGNSGAPGSPGVKGAKGG 413
                    E+GD G  G  G PG++GPPGE GAKGS    G  G+ G PG PGV G  G 
Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS 1281

Query: 414  PGPRGPKGEPGRRGDPGTKGSPGSDGP------------------KGEKGDPGPEGPRGL 455
            PG +G  G+ G  G PG  G PG+ GP                  KG KG+PGP+GP G 
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341

Query: 456  AGEVGNKGAKGD------RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509
             G +G +G  G       RG+PGP G  G LG PG+ G  G  G +G  G  G  GPKG+
Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401

Query: 510  PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPP------ 563
             G  G    G  G PGE GE G +G  G +G  G KG+PG  G  G    PGPP      
Sbjct: 1402 KGHIGLI--GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL 1459

Query: 564  ------GEPGPRGPRGVPGPEGEPGPPGDP 587
                  G PG  GPRG  GP G PGPPG P
Sbjct: 1460 GQKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  288 bits (736), Expect = 2e-77
 Identities = 165/369 (44%), Positives = 187/369 (50%), Gaps = 34/369 (9%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            + G  GP G RG++G  G  G+PG  G  G+ G PGI G  G PG +G PGF G KG  G
Sbjct: 828  LEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPG 887

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G+ G PG  G+ G  G +G+ G  GP G  G  G  G  G  GE G PG  G  G +G
Sbjct: 888  HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG 947

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
             PG  GR G  GE+G  G  G +G +G  G PG KG  G PGP G KG+ G  G  G  G
Sbjct: 948  LPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANG 1007

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
            SPG  GP G  G  G  G  G  G VG  G KG RG  GP GP G  G PG  G  G PG
Sbjct: 1008 SPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPG 1067

Query: 494  DAGP------RGDSGQPGPKGD---------PGRPGF----SYPGPRGAPGEKGEPGPRG 534
             AGP      +GD G PG KG          PG+PG      +PGP GA G +G  GP G
Sbjct: 1068 AAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPG 1127

Query: 535  PEGGRGD---------------FGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEG 579
              G +GD                GL G PG KGE G+    GP G PGPRGP+G  G EG
Sbjct: 1128 LFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEG 1187

Query: 580  EPGPPGDPG 588
             PG PG  G
Sbjct: 1188 TPGLPGGVG 1196



 Score =  287 bits (735), Expect = 2e-77
 Identities = 165/387 (42%), Positives = 197/387 (50%), Gaps = 55/387 (14%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PG  GP G+ G KG  G+ G+ G PG  G++G+ G +G  G PGP GV G +G+ GE G
Sbjct: 870  LPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG 929

Query: 314  ADGRKGAPG---------LAGKNGTDGQKGKLGRIGP------------PGCKGDPGNRG 352
              G +G PG         L G  G +G KG+LG  GP            PG KG PG+ G
Sbjct: 930  PLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPG 989

Query: 353  PDGYPGEAG---------SPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403
            P G  G+ G         SPGERG  G  G  G PG+ G  G +G  G KG +G  G PG
Sbjct: 990  PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPG 1049

Query: 404  S------PGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
                   PG  G  G PG  GP GE G +GD    G+PG  G KG+KGD GP G  G+ G
Sbjct: 1050 PTGKDGIPGPLGPLGPPGAAGPSGEEGDKGD---VGAPGHKGSKGDKGDAGPPGQPGIRG 1106

Query: 458  EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FS 516
              G+ G  G  G  G RGP G  G+ G  G RG  G  GP G  G PGP G+ G  G   
Sbjct: 1107 PAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVG 1166

Query: 517  YPGPRGAPGEKGEPGPRGPE------GGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR- 569
              GP GAPG +G  GP G E      GG G  G  GE G +G+ G+P  PG PG PGP+ 
Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226

Query: 570  --------GPRGVPGPEGEPGPPGDPG 588
                    GP G  GP G+ GPPG+ G
Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDG 1253



 Score =  286 bits (731), Expect = 7e-77
 Identities = 159/378 (42%), Positives = 193/378 (51%), Gaps = 47/378 (12%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI------------------------- 290
           GP GP G+ G  G  G  G PG PG  G +G PG                          
Sbjct: 407 GPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQA 466

Query: 291 --------------EGPIGF---PGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQK 333
                          GP+G    PGP G+PG  G KGE GA+G +G  GL G +G  G+ 
Sbjct: 467 QAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRV 526

Query: 334 GKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSK 393
           GK+GR G  G +G PG+ GP G  G  G PG  G++G +GD G  G+ GPPGE G +G++
Sbjct: 527 GKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAE 586

Query: 394 GYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPR 453
           G  G +G  G PG +G  G  G  GP G PG  G  G  G+ G+ GP GE G PG +G  
Sbjct: 587 GPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNH 646

Query: 454 GLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRP 513
           G  G  G +G  G  G  GP G  G  G PG  G  G PG  GP G+ G  GP G  G P
Sbjct: 647 GSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPP 706

Query: 514 GFSYPGPRGAPGEKGEPGPRGPEGGRGDF---GLKGEPGRKGEKGEPADPGPPGEPGPRG 570
           G  YPGPRG  G  G  G +G +G +G+    G KG+ G KG++G+P  PGP GE GP G
Sbjct: 707 G--YPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764

Query: 571 PRGVPGPEGEPGPPGDPG 588
           P+G  G  GE GPPG  G
Sbjct: 765 PKGQAGQAGEEGPPGSAG 782



 Score =  233 bits (594), Expect = 5e-61
 Identities = 123/269 (45%), Positives = 143/269 (53%), Gaps = 9/269 (3%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            IPGP G  G +G  G  G  G PG+ G  G  G  G  GP G PG  G PG  G  G  G
Sbjct: 1221 IPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDG 1280

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
            + G KG PG  G  G  G  G+ G  GPPG +G  G+ G +G  GE G+ GE G  G  G
Sbjct: 1281 SPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPG 1340

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
              G  G RGPPG +G +G +G  G  G PG  G  G  G PGP GP G PG +GD G KG
Sbjct: 1341 RTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG 1400

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP---------G 484
              G  G  G  G PG  G +G  G  G +G  G +G PGP GP G+LG P         G
Sbjct: 1401 EKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLG 1460

Query: 485  KQGSRGDPGDAGPRGDSGQPGPKGDPGRP 513
            ++GS+G PG  GPRGD+G  GP G PG P
Sbjct: 1461 QKGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  212 bits (540), Expect = 1e-54
 Identities = 139/361 (38%), Positives = 166/361 (45%), Gaps = 97/361 (26%)

Query: 265 GQKGAKGNMGEPGEPG--QKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPG 322
           G+KGAKG      EP   +KG+Q     EGP G PGP+GV G  G               
Sbjct: 373 GEKGAKG------EPAVIEKGQQ----FEGPPGAPGPQGVVGPSGPP------------- 409

Query: 323 LAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG----------- 371
                            GPPG  GDPG  GP G PG  G  G RG  G            
Sbjct: 410 -----------------GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGG 452

Query: 372 --KGDP--------------GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPG 415
             KG P               +   +GPPG +G  G  G     G PG PG+KG +G  G
Sbjct: 453 SFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPG---PVGLPGHPGLKGEEGAEG 509

Query: 416 PRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRG 475
           P+GP+G  G  G PG  G         + G PG +G RGL G+ G KG +G  GLPG  G
Sbjct: 510 PQGPRGLQGPHGPPGRVG---------KMGRPGADGARGLPGDTGPKGDRGFDGLPGLPG 560

Query: 476 PQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRG 534
            +G  G+ G  G  G PG+ G RG  G PGP G  G PG     GPRG+PG  G PG   
Sbjct: 561 EKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVT- 619

Query: 535 PEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPE------GEPGPPGDPG 588
                   G+ G PG KG  G P +PGPPG+ G  G +G+PGP+      GE GPPG+PG
Sbjct: 620 --------GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPG 671

Query: 589 L 589
           +
Sbjct: 672 I 672



 Score =  177 bits (448), Expect = 5e-44
 Identities = 124/296 (41%), Positives = 139/296 (46%), Gaps = 65/296 (21%)

Query: 345 KGDPGNRGPDGYPGEAGS-------PGERGDQGGKGDPG--RPGRR--GPPGEIGAKGSK 393
           +GD    GPD    E  S       PG  G++G KG+P     G++  GPPG   A G +
Sbjct: 345 EGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFEGPPG---APGPQ 400

Query: 394 GYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR---RGDPGT-------------KGSPGS 437
           G  G SG PG PG  G  G PGP G  G PG    RG PGT             KG P S
Sbjct: 401 GVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVS 460

Query: 438 -----------------DGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGAL 480
                             GP G  G  G  GP GL G  G KG +G  G  GPRG QG  
Sbjct: 461 FQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPH 520

Query: 481 GEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRG 540
           G PG+ G  G PG  G RG  G  GPKGD G     + G  G PGEKG+         RG
Sbjct: 521 GPPGRVGKMGRPGADGARGLPGDTGPKGDRG-----FDGLPGLPGEKGQ---------RG 566

Query: 541 DFGLKGEPGRKGEKGE---PADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           DFG  G+PG  GE GE      PGP G+ G  GPRG+ GP G PGP G PG+T  D
Sbjct: 567 DFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID 622



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 42/105 (40%), Positives = 52/105 (49%), Gaps = 15/105 (14%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            GE   +  + + GP G     G+KG +G  G  G PG KG  G PG  G +G PGP GV 
Sbjct: 1400 GEKGHIGLIGLIGPPGEA---GEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVA 1456

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDP 348
            G  G+KG       KG+P      G+ G +G  G  GPPG  G P
Sbjct: 1457 GPLGQKGS------KGSP------GSMGPRGDTGPAGPPGPPGAP 1489


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  308 bits (788), Expect = 2e-83
 Identities = 176/405 (43%), Positives = 203/405 (50%), Gaps = 58/405 (14%)

Query: 244 GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
           GE      +   GP GP+G  G++G  G  G PG+ G  G  G PG  GP+G PG  G P
Sbjct: 321 GEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFP 380

Query: 304 GFKGEKGEFGADGRKG------------------APGLAGKNGTDGQKGKLGRIGPPGCK 345
           G  G KGE G  G +G                  +PGL G  GTDG  G  G  G PG  
Sbjct: 381 GNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS 440

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
           G PG+ GP G PG  GS G +G +G  GDPG PG +G  G  G  G  G QG  G PG  
Sbjct: 441 GPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE 500

Query: 406 GVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSD---GPKGEKGDPGPEGPRGLAGEVGNK 462
           G +G +G PG  GP G  G RG PG +G PGSD   GPKG +G+ GP G  G  G  G+ 
Sbjct: 501 GKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDP 560

Query: 463 GAKGDRGLP------------GPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ---PGPK 507
           G  G+ GLP            GP G  G LG PG+ G  G PG  G RG  G    PGPK
Sbjct: 561 GRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPK 620

Query: 508 ---GDPGRPG----FSYPGPRGAPGEKGEPGP---------------RGPEGGRGDFGLK 545
              GDPG+PG       PG RGAPG+ GE GP               +GP G  G  GL 
Sbjct: 621 GSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680

Query: 546 GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLT 590
           G PG  GE G+P D G PG+PG  GP G  G  G PG  G+PG+T
Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGIT 725



 Score =  307 bits (786), Expect = 3e-83
 Identities = 173/360 (48%), Positives = 195/360 (54%), Gaps = 35/360 (9%)

Query: 256  GPSGPKGYRGQKGAKGN---MGEPGEPGQKGRQGDPGIEGPIGFPGP---KGVPGFKGEK 309
            GP+G  G+ G +G  G     GEPGEPGQKG  G PG +G  G PGP    GVPG KG +
Sbjct: 840  GPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR 899

Query: 310  GEFG---------ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------RGPD 354
            G  G         + GR G PG AG  G  G  G+ G+ GPPG +GDPG+      RGP 
Sbjct: 900  GTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPA 959

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
            G P   G PG++GD G  G PG  G  GP G  G +G  G  G  G  G PG+ G  G P
Sbjct: 960  GPP---GGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTP 1016

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
            G  GP G  G +G PG  G PGS+GP GE G  GP G  G  G  G  G +GDRG PGP 
Sbjct: 1017 GKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPA 1076

Query: 475  GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
            G  G+ G PG  G  G PGDAG RGD G  GP G PGR      G RG PG +G  G +G
Sbjct: 1077 GLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR-----AGKRGLPGPQGPRGDKG 1131

Query: 535  PEGGRGDFGLKGEPGRKGEKGEPADPGPPGE------PGPRGPRGVPGPEGEPGPPGDPG 588
              G RGD G KG  G  G +G P  PGP GE      PGP GPRG PGP G  G  G+PG
Sbjct: 1132 DHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPG 1191



 Score =  306 bits (784), Expect = 5e-83
 Identities = 165/366 (45%), Positives = 198/366 (54%), Gaps = 31/366 (8%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDP------GIEGPIGFPGPKGVPGFKGE 308
           PG  GP G  G +G +G  G+PGE G+ GR G+P      G  G  GFPG  G+PG KG 
Sbjct: 242 PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGH 301

Query: 309 KGEFGADGRK---GAPGLAGKNGTDGQKGKLGRIGPPGCKGD---------PGNRGPDGY 356
           +G  G +G K   GAPG  G+ G  G  G +G +GP G  G+         PG RG  G 
Sbjct: 302 RGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGM 361

Query: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNS---------GAPGSPGV 407
           PG+ G  G  G  G  G PG PG +G  G  GA+G +G QG           G+PG PG 
Sbjct: 362 PGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGA 421

Query: 408 KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
            G  G PG +GP G PG  G PG+ G PGS GP+G  G  G  G  G  G  G KG  G 
Sbjct: 422 IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481

Query: 468 RGLPGPRGPQGALGEP---GKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGA 523
           +G PGP G QG +G P   GK+G RGDPG  GP G  G+ G  G+ G PG    PGP+GA
Sbjct: 482 KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGA 541

Query: 524 PGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGP 583
            GE+G  G  GP+G +GD G  GEPG  G +G   +PG  G  G  GP G PG +G PGP
Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGP 601

Query: 584 PGDPGL 589
           PG  G+
Sbjct: 602 PGSIGI 607



 Score =  303 bits (776), Expect = 4e-82
 Identities = 175/379 (46%), Positives = 198/379 (52%), Gaps = 53/379 (13%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  GP+G  G  GA G  G PG PG  G +G PG    +G PGPKG  G  G+ GE G 
Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG---SMGLPGPKGSSGDPGKPGEAG- 633

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP------DGYPGEAGSPGERGD 368
               G PG  G  G DG+ G  G +GPPG  G+ G +GP       G PG  G PGE G 
Sbjct: 634 --NAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691

Query: 369 QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD 428
            G +G PG PG  GP G  G +G+ G +G  G  G PG KG  GG GP GPKG PG  G 
Sbjct: 692 PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751

Query: 429 PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD------RGLPGPRGPQGALG- 481
           PG  G PG  G  GE+G  G  GP+G  G +G KGA+G       RGLPGP GP G  G 
Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811

Query: 482 -----EPGKQG------SRGDPGD------------AGPRGDSGQPGPKGDPGRPGFSYP 518
                EPG +G      SRG+PG             AGP+G  GQPG KG+PG PG    
Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPG--QK 869

Query: 519 GPRGAPGEK---GEPGPRGP------EGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR 569
           G  G+PG +   G PGP GP      +GGRG  G  G  G  G  G    PGP G PGP 
Sbjct: 870 GDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPA 929

Query: 570 GPRGVPGPEGEPGPPGDPG 588
           GP G PG EG PG  GDPG
Sbjct: 930 GPLGEPGKEGPPGLRGDPG 948



 Score =  301 bits (771), Expect = 2e-81
 Identities = 168/357 (47%), Positives = 193/357 (54%), Gaps = 17/357 (4%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            GE  K     +PG  G  G  G +G +GN GE GEPG  G  G+ G+ G  G  GPKG P
Sbjct: 687  GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP 746

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
            G  G  G+ G  G +G PG  G  GT G KG  G IG  G +G  GN G  G PG  G P
Sbjct: 747  GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPP 806

Query: 364  GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
            G  G  G KG+PG  G  GPPG  G  GS+G  G +GA G  G +G  G PG +G  GEP
Sbjct: 807  GPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEP 866

Query: 424  GRRGD---PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGA- 479
            G++GD   PG +G  GS GP G  G PG +G RG  G  G  G  G  G  GP GP GA 
Sbjct: 867  GQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAP 926

Query: 480  -----LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEP---G 531
                 LGEPGK+G  G  GD G  G  G  GP G PG      PG +G PGE G+P   G
Sbjct: 927  GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG-----PGDKGDPGEDGQPGPDG 981

Query: 532  PRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            P GP G  G  G+ G PG++GE+G P  PGP G PG  GP G  G +G PGP G PG
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG 1038



 Score =  299 bits (766), Expect = 6e-81
 Identities = 167/366 (45%), Positives = 199/366 (54%), Gaps = 34/366 (9%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPG----------- 304
           GP G  G +G +G  G  GEPG PG +G  G+PG++GP G  GP G PG           
Sbjct: 546 GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI 605

Query: 305 -FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
             +G+ G  G  G KG+ G  GK G  G  G  G+ G PG  G+ G  GP G PG AG  
Sbjct: 606 GIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGER 665

Query: 364 GERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP 423
           GE+G  G  G  G PG  GPPGE G  G +G  G+ GA G  G +G +G PG RG   EP
Sbjct: 666 GEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG---EP 722

Query: 424 GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGL---PGPRGPQGAL 480
           G  G PG KG  G  GP G KG PGP G  G  G  G +G  G+RG+   PGP+G +G +
Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782

Query: 481 GEPGKQ------GSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGEPGP- 532
           GE G +      G+RG PG  GP G +G  G KG+PG  G    PG RG PG +GE GP 
Sbjct: 783 GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842

Query: 533 -----RGPEGGRGDFGLKGEPGRKGEKGEPADPGP---PGEPGPRGPRGVPGPEGEPGPP 584
                 GP+G  G  G+KGEPG  G+KG+   PGP    G PGP GP GVPG +G  G  
Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQ 902

Query: 585 GDPGLT 590
           G PG T
Sbjct: 903 GPPGAT 908



 Score =  299 bits (766), Expect = 6e-81
 Identities = 172/400 (43%), Positives = 200/400 (50%), Gaps = 67/400 (16%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPG----------- 304
            GP GP+G RG  G +G  G  G PG+KG  G  G +GP G PGP G PG           
Sbjct: 705  GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764

Query: 305  -------FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGR---IGPPGCKGDPGNRGPD 354
                     G KG+ G  G KGA G AG +G  G  G LG     GP G KG+PG RG  
Sbjct: 765  GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLV 824

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
            G PG  G+PG RG+ G  G  G  G +GP G+ G KG  G  G  G  GSPG +G  G P
Sbjct: 825  GPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSP 884

Query: 415  GPRGPKGEPGRRGDPGTKGSP------------------GSDGPKGEKGDPGPEGPRGLA 456
            GP GP G PG +G  GT+G P                  G+ GP G  G+PG EGP GL 
Sbjct: 885  GPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944

Query: 457  GEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQ------PGPKGDP 510
            G+ G+ G  GDRG  GP G  G  G+PG+ G  G  G  GP G +GQ      PG +G+ 
Sbjct: 945  GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004

Query: 511  GRPGFSYP-------GPRGAPGEKGEPGP------------RGPEGGRGDFGLKGEPGRK 551
            G PG   P       GP GA G+KG PGP             GPEG  G+ G  G  G  
Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064

Query: 552  GEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPP---GDPG 588
            GE+G+  DPGP G PG +G  G PGP G PG     GDPG
Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPG 1104



 Score =  295 bits (754), Expect = 2e-79
 Identities = 168/383 (43%), Positives = 200/383 (52%), Gaps = 49/383 (12%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  GP+G  G +G +G  G+PG PG KG  G  G  GP G  GP G PG +G++G  G 
Sbjct: 449 PGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGD 508

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS------PGERGD 368
            G  G PG  G+ G  G +G  G  G PG KG  G RGP G  G  GS      PGE G 
Sbjct: 509 PGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL 568

Query: 369 QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG---PGPRGPKGEPGR 425
            G +G  G PG +GP G++G  G+ G  G  G PGS G++G  G    PGP+G  G+PG+
Sbjct: 569 PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK 628

Query: 426 RGDPGTKGSPG---SDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGA 479
            G+ G  G PG   + G  GE G  GP GP GLAGE G +G  G    +GLPGP GP G 
Sbjct: 629 PGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE 688

Query: 480 LGEPGKQGSRGDPGDAGP---RGDSGQPG------------------------PKGDPGR 512
            G+PG QG  GDPG  GP   RG+ G PG                        PKG PG 
Sbjct: 689 GGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGP 748

Query: 513 PG----FSYPGPRGAPGEK---GEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
            G       PG +G PGE+   G PGP+G  GG G+ G +G  G  G +G P   GPPG 
Sbjct: 749 SGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGP 808

Query: 566 PGPRGPRGVPGPEGEPGPPGDPG 588
            GP G +G PGP G  GPPG  G
Sbjct: 809 AGPTGEKGEPGPRGLVGPPGSRG 831



 Score =  294 bits (753), Expect = 2e-79
 Identities = 172/413 (41%), Positives = 199/413 (48%), Gaps = 79/413 (19%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGPKGVPGFKGEKGE 311
           PGP GP G RG +G  G  GE GEPG+ G  G+ G  G  G   FPG  G+PG KG +G 
Sbjct: 245 PGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGH 304

Query: 312 FGADGRKG---APGLAGKNGTDGQKGKLGRIGPPGCKGD---------PGNRGPDGYPGE 359
            G +G KG   APG  G+ G  G  G +G +GP G  G+         PG RG  G PG+
Sbjct: 305 KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGK 364

Query: 360 AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSG---------APGSPGVKGA 410
            G  G  G  G  G PG PG +G  G  GA+G +G QG  G         +PG PG  G 
Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT 424

Query: 411 KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGE------------------------KGD 446
            G PG +GP G PG  G PG+ G PGS GP+G                         KG+
Sbjct: 425 DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGE 484

Query: 447 PGP---EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGK---------------QGS 488
           PGP   +GP G  GE G +G +GD G  GP GP G  G PG                QG 
Sbjct: 485 PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544

Query: 489 RGDPGDAGPRGDSGQPGPKGDP---------GRPGFSYP----GPRGAPGEKGEPGPRGP 535
           RG  G +GP+G  G PG  G+P         G PG   P    GP GAPGE G PGP G 
Sbjct: 545 RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604

Query: 536 EGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G RG  G  G PG KG  G+P  PG  G  G  G RG PG +GE GP G  G
Sbjct: 605 IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVG 657



 Score =  283 bits (725), Expect = 4e-76
 Identities = 156/347 (44%), Positives = 184/347 (53%), Gaps = 19/347 (5%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
            G  GP G  G  G  G +GEPG+ G  G +GDPG  G +G  GP G PG  G+KG+ G D
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974

Query: 316  GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDP 375
            G+ G  G  G  GT GQ+G +G  G  G +G PG  GP G PG+ G  G  GD+G  G  
Sbjct: 975  GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV 1034

Query: 376  GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
            G PG  GP GE    G +G  GN G PG  G  G +G  G  GP G PG +G PGT G  
Sbjct: 1035 GPPGSNGPVGE---PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPV 1091

Query: 436  GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
            G+ G  G++GDPG  GP      +G  G  G RGLPGP+GP+G  G+ G +G RG  G  
Sbjct: 1092 GAPGDAGQRGDPGSRGP------IGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHR 1145

Query: 496  GPRGDSGQPGPKGDPGRPGFS-YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554
            G  G  G PGP G  G  G +  PGP G  G  G  GP G EG  G  G  G PG +G  
Sbjct: 1146 GFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSV 1205

Query: 555  GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRET 601
            GE    GPPGEPGP GP         PGPPG       D+M +  E+
Sbjct: 1206 GEAGPEGPPGEPGPPGP---------PGPPGHLTAALGDIMGHYDES 1243



 Score =  281 bits (718), Expect = 2e-75
 Identities = 172/403 (42%), Positives = 194/403 (48%), Gaps = 64/403 (15%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKG------- 307
           PGP+GP G +G +G +G  G PG  G +G  G+PG+ G  G PGP G P   G       
Sbjct: 131 PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRP 190

Query: 308 ---------EKGEFGAD-----GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP 353
                    EK   G+      G  G  G  G  G  GQ+G  G  GPPG  GDPG  GP
Sbjct: 191 FSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGP 250

Query: 354 ---------------DGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGN 398
                          DG PG  G+PGE G  G  G  G PG  G PG  G +G KG +G 
Sbjct: 251 IGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310

Query: 399 SGAPGSPGVKGAKG--GP----GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP 452
            G  G+PG KG  G  GP    GP GP+G PG RG  G +G+PG  G  G  G PGP GP
Sbjct: 311 KGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGP 370

Query: 453 RGLAGEVG------NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506
            G+ G  G       KG  G  G  GP GPQG  GE G  G  G PG  G  G  G PG 
Sbjct: 371 LGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGA 430

Query: 507 KGDPGRPGFSYP----GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPG- 561
           KG  G PG S P    GP G+PG +G  GP+G  G  GD G+ G  G  G KGEP   G 
Sbjct: 431 KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI 490

Query: 562 -----PPGEPGPRGPRG------VPGPEGEPGPPGDPGLTECD 593
                PPGE G RGPRG       PGP GE G PG+ G    D
Sbjct: 491 QGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSD 533



 Score =  239 bits (611), Expect = 6e-63
 Identities = 136/298 (45%), Positives = 157/298 (52%), Gaps = 32/298 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGE------PGEPGQKGRQGDPGIEGPIGFPGPKG------- 301
            PG  GP G RG  G+ G +G+      PG PG KG  G+ G  GP G PGP G       
Sbjct: 935  PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGI 994

Query: 302  --VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG---DPGNRGP--- 353
              +PG +GE+G  G  G  G PG  G  G  G KG  G +GPPG  G   +PG  GP   
Sbjct: 995  VGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGN 1054

Query: 354  DGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGS------PGV 407
            DG PG  G+ GERGD+G  G  G PG +G PG  G  G+ G  G  G PGS      PG 
Sbjct: 1055 DGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGR 1114

Query: 408  KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
             G +G PGP+GP+G+ G  GD G +G  G  G  G +G PGP GP G  G  G  G  G 
Sbjct: 1115 AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGP 1174

Query: 468  RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPG 525
            RG PGP GP G  G PG  G  G P   G RG  G+ GP+G PG PG   PGP G PG
Sbjct: 1175 RGPPGPVGPSGKEGNPGPLGPIGPP---GVRGSVGEAGPEGPPGEPG--PPGPPGPPG 1227



 Score =  239 bits (610), Expect = 8e-63
 Identities = 151/359 (42%), Positives = 174/359 (48%), Gaps = 32/359 (8%)

Query: 244 GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
           GEC  V C + PG       RG+KG KG      EPG       P + G  G PGP G P
Sbjct: 90  GECCPV-CSQTPGGGNTNFGRGRKGQKG------EPGLV-----PVVTGIRGRPGPAGPP 137

Query: 304 GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDG----YPGE 359
           G +G +GE G  GR   PG  G  G DG+ G  G+ G PG  G P + GPDG    +  +
Sbjct: 138 GSQGPRGERGPKGR---PGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194

Query: 360 AGSPGERGDQGGK-----GDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
                E+   G +     G  G  G RGP G  G +G  G  G  G PG PG  G  G  
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSR 254

Query: 415 GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
           GP GP G+PG  G+PG  G+PG     G  G PG  G  G  G  G KG +G +GL GP+
Sbjct: 255 GPEGPPGKPGEDGEPGRNGNPGE---VGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 475 GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
           G  GA G  G+ G  G  G  GP G  G PG +G  G  G   PG RGA G  G+PGP G
Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGA--PGQRGAHGMPGKPGPMG 369

Query: 535 PEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           P G  G  G  G PG KGE G     GP G   P+G RG  GP G  G PG PG    D
Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEG---PQGQRGETGPPGPVGSPGLPGAIGTD 425



 Score =  201 bits (510), Expect = 3e-51
 Identities = 121/293 (41%), Positives = 147/293 (50%), Gaps = 24/293 (8%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGF------PGPKGVPGFKGE 308
            PGP+G  G RG  G  G  GE G PG  G  G PG  GP G       PGP G PG  G 
Sbjct: 983  PGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGP---PGCKGDPGNRGPDGYPGEAGSPGE 365
             GE G +G  G  G  G++G  G++G  G  GP   PG +G PG  GP G PG+AG  G+
Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD 1102

Query: 366  RGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKG---AKGGPGPRGPKGE 422
             G +G  G PGR G+RG PG  G +G KG  G+ G  G  G +G    +G PGP GP GE
Sbjct: 1103 PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE 1162

Query: 423  PGRRGDPGT---KGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGA 479
             G  G PG    +G PG  GP G++G+PGP GP G  G  G+ G  G  G PG  GP G 
Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGP 1222

Query: 480  LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGP 532
             G PG   +    GD     D   P P  +       +   + AP +K +  P
Sbjct: 1223 PGPPGHLTAA--LGDIMGHYDESMPDPLPE-------FTEDQAAPDDKNKTDP 1266



 Score =  190 bits (483), Expect = 4e-48
 Identities = 116/266 (43%), Positives = 133/266 (50%), Gaps = 15/266 (5%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP+G  G  G  GA G+ G PG  G  G  G  G  GP G  G  G PG  G  GE G
Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G  G  GL G  G  G  G +G  G  G +GDPG+RGP G PG AG  G  G QG +G
Sbjct: 1069 DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRG 1128

Query: 374  DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
            D G  G RG  G+ G +G  G QG  G PG  G +G+ G PGP GP+G PG  G  G +G
Sbjct: 1129 DKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEG 1188

Query: 434  SPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQG----ALGEPGKQGSR 489
            +PG  GP       GP G RG  GE G +G  G+ G PGP GP G    ALG+       
Sbjct: 1189 NPGPLGP------IGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDE 1242

Query: 490  GDPGDAGPRGDSGQPGP----KGDPG 511
              P D  P     Q  P    K DPG
Sbjct: 1243 SMP-DPLPEFTEDQAAPDDKNKTDPG 1267


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score =  308 bits (788), Expect = 2e-83
 Identities = 172/374 (45%), Positives = 202/374 (54%), Gaps = 48/374 (12%)

Query: 261 KGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGA 320
           +G  G++G  G  G PG PG  G  GD G +GP G PGP G PG  G  G+ G  G  G 
Sbjct: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84

Query: 321 PGLAGKNGTDGQKGKLGRIGPPGCKGDPGN--RGPDGYPGEAGSPGERGDQGGKGDPGRP 378
            G  G  G+ G KG+ G  G PG +G PG    GP G PG AG PGE G  G  GDPGR 
Sbjct: 85  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144

Query: 379 GRRGPPGEIGAKGSKGYQ------------GNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
           G  GPPG  G +G+ G+             G SG PG PG++G KG    +G  GEPGR+
Sbjct: 145 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA---KGEIGEPGRQ 201

Query: 427 GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQ 486
           G  G +G  G  G  G +G PG +G RG+ G VG+KG KG RGL G  GPQG  G PG Q
Sbjct: 202 GHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ 261

Query: 487 GSRGDPGDAGPRGDSGQ---------PGPKGDPGRPGF----SYPGPRGAPGEKGEPGP- 532
           G RG PG+AGP+GD G          PGPKGD G PG       PG  G  GE G+PGP 
Sbjct: 262 GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 321

Query: 533 -----------------RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVP 575
                            +G  G +G  G  G+PG+ G  G+P   GPPGE GPRGP+G+P
Sbjct: 322 GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 381

Query: 576 GPEGEPGPPGDPGL 589
           G  GE GP G PGL
Sbjct: 382 GSRGELGPVGSPGL 395



 Score =  288 bits (736), Expect = 2e-77
 Identities = 168/381 (44%), Positives = 195/381 (51%), Gaps = 47/381 (12%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP---IGF------------PG 298
           IPGP GP G  G  G  G +G  G+PG++G  G PG  GP   IGF            PG
Sbjct: 116 IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPG 175

Query: 299 PKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIG---PPGC----------- 344
             G PG  G +G  GA G  G PG  G  G +G +G+LG +G   PPG            
Sbjct: 176 RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVG 235

Query: 345 -KGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403
            KG+ G RG DG PG  G PG  GDQG +G PG  G +G  G  GA+G  G  G  G  G
Sbjct: 236 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 295

Query: 404 SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS------PGSDGPKGEKGDPGPEGPRGLAG 457
            PGV G  G PG  G KGEPG+ G PG  G       PG  G KG  G+ G  G  G  G
Sbjct: 296 LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG 355

Query: 458 EVGNKGAKGDRGLPG---PRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG 514
           ++GN G  G +G PG   PRGPQG  G  G+ G  G PG  G  G  G PG  G PG PG
Sbjct: 356 QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG 415

Query: 515 FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGE------KGEPADPGPPGEPGP 568
              PG +G  G  GEPGP+G +G  G+ G  GE G  G+      KG   +PG PG  GP
Sbjct: 416 L--PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473

Query: 569 RGPRGVPGPEGEPGPPGDPGL 589
            G RG+PG EG  GPPG  G+
Sbjct: 474 EGSRGLPGVEGPRGPPGPRGV 494



 Score =  283 bits (725), Expect = 4e-76
 Identities = 161/357 (45%), Positives = 186/357 (52%), Gaps = 21/357 (5%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF---------K 306
           G  G  G RG KGAKG +GEPG  G KG +GD G  G +G  GP G  G          K
Sbjct: 178 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 237

Query: 307 GEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGER 366
           GEKG  G DG  G  GL G  G  GQ+G  G  GP G +G  G RG  G PG  G  G  
Sbjct: 238 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297

Query: 367 GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRR 426
           G  G  G PG PG +G PG+ G  G  G QG    PG PG+ GAKG  G +G  G PG+ 
Sbjct: 298 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG---LPGVPGIPGAKGVAGEKGSTGAPGKP 354

Query: 427 GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQ 486
           G  G  G PG  GP GE G   P GP+GL G  G  G  G  GLPG  G  G+ G PG  
Sbjct: 355 GQMGNSGKPGQQGPPGEVG---PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411

Query: 487 GSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLK 545
           G  G PG  G RG  G+PGPKG+ G  G     G RG  G+ G PGP+G  G  G+ GL+
Sbjct: 412 GPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR 471

Query: 546 GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETC 602
           G    +G +G P   GP G PGPRG +G  G  G PG  G PG    D   ++++ C
Sbjct: 472 GP---EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTD--QHIKQVC 523



 Score =  282 bits (721), Expect = 1e-75
 Identities = 169/393 (43%), Positives = 195/393 (49%), Gaps = 56/393 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG +GPKG RG +GA+G  G PG  G  G  G  G +G  G PG KG PG  G  G+ G 
Sbjct: 267 PGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL 326

Query: 315 DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            G  G PG+ G  G  G+KG  G  G PG  G+ G  G  G PGE G  G +G  G +G+
Sbjct: 327 QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 386

Query: 375 PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
            G  G  G PG++G+ GS G  G  G PG PG+KG +G  G  GPKGE G  G+ G  G 
Sbjct: 387 LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE 446

Query: 435 PGS------DGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
            G        GPKG  G+PG  G RG  G  G  G +G RG PGPRG QG  G  G  G 
Sbjct: 447 RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 506

Query: 489 RGDPG------------------------------DAGPRGDSGQPGPKGDPGRPGFS-Y 517
           +G PG                              D+G  G  G+PGP G PG PG + +
Sbjct: 507 QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 566

Query: 518 PGP---RGAPGEKGEPGPRGPEGGRGDFGLKGE---PGR-----KGEKGEPADPGPP--- 563
           PG    RG PG KG PG  G  G +GD G KGE   PGR      G  G P DPGP    
Sbjct: 567 PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYG 626

Query: 564 -----GEPGPRGPRGVPGPEGEPGPPGDPGLTE 591
                GE GP G  G+PG  G PGPPG PG  E
Sbjct: 627 RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 659



 Score =  276 bits (705), Expect = 7e-74
 Identities = 176/422 (41%), Positives = 208/422 (49%), Gaps = 86/422 (20%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG---FPGPKGVPGFKGEKG 310
           I G  G KG RG  G  G  G PG PG +G++G PG  GP G     G +G+PG  G KG
Sbjct: 233 IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKG 292

Query: 311 EFG---ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERG 367
           + G    DGR G PG+ G  G  G+ G  G  G  G  G PG  G  G  GE GS G  G
Sbjct: 293 DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG 352

Query: 368 DQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSG------APGSPGVKGAKGGPGPRG--- 418
             G  G+ G+PG++GPPGE+G +G +G  G+ G      +PG PG  G+ G PG  G   
Sbjct: 353 KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 412

Query: 419 PKGEPGRRGD------PGTKGSPGSDGPKGEKGD---------PGPEGPRGLAGEVGNKG 463
           P G PG +GD      PG KG  G+ G +GE G+         PGP+G  G  GE G +G
Sbjct: 413 PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 472

Query: 464 AKGDRGLP---GPRGPQGALGEPGKQGSRGDPG--------------------------- 493
            +G RGLP   GPRGP G  G  G+QG+ G PG                           
Sbjct: 473 PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA 532

Query: 494 ---------DAGPRGDSGQPGPKGDPGRPGFS-YPGP---RGAPGEKGEPGPRGPEGGRG 540
                    D+G  G  G+PGP G PG PG + +PG    RG PG KG PG  G  G +G
Sbjct: 533 EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 592

Query: 541 DFGLKGE---PGR-----KGEKGEPADPGPP-----GEPGPRGPRGVPGPEGEPGPPGDP 587
           D G KGE   PGR      G  G P DPGP      G  G RGP GV G  G PGPPG P
Sbjct: 593 DLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 652

Query: 588 GL 589
           GL
Sbjct: 653 GL 654



 Score =  270 bits (690), Expect = 4e-72
 Identities = 169/432 (39%), Positives = 202/432 (46%), Gaps = 99/432 (22%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGF---KGEKG 310
           +PG  G  G RG KG  G  G  GEPG+ G  G PG  G  G  GP G PG    KG+KG
Sbjct: 42  VPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKG 101

Query: 311 EFGADGRKGAPGLA-----GKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS--- 362
           E G  G +G PG       G  GT G  G+LGR+GP G   DPG RGP G PG  G    
Sbjct: 102 EPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVG---DPGRRGPPGPPGPPGPRGT 158

Query: 363 ------------------------PGERGDQGGKGDPGRPGRRG---------------- 382
                                   PG RG +G KG+ G PGR+G                
Sbjct: 159 IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 218

Query: 383 --PPGEIGAKG------SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGR------RGD 428
             PPG  G +G       KG +G  G  G PG +G  G PG +G +G PG       RG 
Sbjct: 219 QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 278

Query: 429 PGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGS 488
            G +G PG  GPKG+ G PG +G  G+ G  G KG  G  G PG  G QG  G PG  G+
Sbjct: 279 EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA 338

Query: 489 RGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-------GPRGAPGEKGE------------ 529
           +G  G+ G  G  G+PG  G+ G+PG   P       GP+G PG +GE            
Sbjct: 339 KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 398

Query: 530 ------------PGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGP 577
                       PGP G  G +GD G+ GEPG KGE+G   + G  GE G  G  G+PGP
Sbjct: 399 LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458

Query: 578 EGEPGPPGDPGL 589
           +G  G PG+PGL
Sbjct: 459 KGSAGNPGEPGL 470



 Score =  245 bits (625), Expect = 1e-64
 Identities = 145/346 (41%), Positives = 168/346 (48%), Gaps = 50/346 (14%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
           +PG  G  G +G  G KG+ G PG+PGQ G  G PG +GP G  GP+G  G  G +GE G
Sbjct: 329 LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELG 388

Query: 314 ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
             G  G PG  G  G+ G  G  G  G PG KGD G  G  G  GE G+ GE G+ G +G
Sbjct: 389 PVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERG 448

Query: 374 DPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKG 433
           + G  G  GP G  G  G  G +G  G+ G PGV+G +G PGPRG +GE G  G PG +G
Sbjct: 449 ELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQG 508

Query: 434 SPG------------------------------SDGPKGEKGDPGPEGPRGLAGEVGNKG 463
            PG                                G  G  G PGP GP G  GE G  G
Sbjct: 509 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568

Query: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP--RGDSGQPGPKGDPGRPGFSYPGPR 521
             G RGLPG +GP GALG  G +G  G+ G+ GP  RG +G PG  G PG PG   P   
Sbjct: 569 QMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG---PASY 625

Query: 522 GAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPG 567
           G  G  GE GP               PG  G  G P  PGPPG PG
Sbjct: 626 GRNGRDGERGP---------------PGVAGIPGVPGPPGPPGLPG 656



 Score =  190 bits (482), Expect = 5e-48
 Identities = 111/248 (44%), Positives = 131/248 (52%), Gaps = 39/248 (15%)

Query: 380 RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439
           +RGPPGE G  G  G  G  G  G  G +G KG PGP GP GEPG+ G PG  G+PG+DG
Sbjct: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83

Query: 440 PKGEKGDPGPEGPRGLAGEVGNKGAKG--DRGLPGPRGPQGALGEP---GKQGSRGDPGD 494
             G  G PG  G +G  GE G  G++G   RG+PGP GP G  G P   G+ G  GDPG 
Sbjct: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 143

Query: 495 AGPRGDSGQPGPKG---------------DPGRPGF-SYPGPR---GAPGEKGEPGPRGP 535
            GP G  G PGP+G                PGR G+   PG R   GA GE GEPG +G 
Sbjct: 144 RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 203

Query: 536 EGGRGDFGLKGEPGRK---------------GEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
           +G  GD G  GE G +               G+KGE    G  GEPGP+G  G PG +G+
Sbjct: 204 KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 263

Query: 581 PGPPGDPG 588
            GPPG+ G
Sbjct: 264 RGPPGEAG 271



 Score =  176 bits (446), Expect = 8e-44
 Identities = 115/311 (36%), Positives = 134/311 (43%), Gaps = 65/311 (20%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGAD 315
           GP GP+G  G +G  G +G PG PG+ G  G PG+ G    PGP G+PG KG++G  G  
Sbjct: 373 GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEP 429

Query: 316 GRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGN------------------------- 350
           G KG  G +G+ G  G++G+LG IG PG KG  GN                         
Sbjct: 430 GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPP 489

Query: 351 --RGPDGYPGEAGSPGERG---------------------------------DQGGKGDP 375
             RG  G  G  G PG +G                                 D G  G P
Sbjct: 490 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 549

Query: 376 GRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
           GRPG  GPPG  G  G  G  G  G PG  G  GA G  GP+G  GE G RG PG +G  
Sbjct: 550 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPN 608

Query: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
           G  G  G  GDPGP    G  G  G +G  G  G+PG  GP G  G PG          A
Sbjct: 609 GLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA 667

Query: 496 GPRGDSGQPGP 506
           G R  +  P P
Sbjct: 668 GQRAFNKGPDP 678



 Score =  134 bits (337), Expect = 3e-31
 Identities = 87/237 (36%), Positives = 104/237 (43%), Gaps = 29/237 (12%)

Query: 244 GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
           GE  ++  + +PGP G  G  G+ G +G  G  G PG +G +G PG  G  G  G  G+P
Sbjct: 445 GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 504

Query: 304 GFKGEKGEFGADGR--------------KGAPGL----AGKNGTDGQKGKLGRIGPPGCK 345
           G +G  G    D                + A  L    +G  G  G+ G  G  GPPG  
Sbjct: 505 GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN 564

Query: 346 GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
           G PG  G  G PG  G PG  G +G KGD G  G RGPPG    +G  G  G  G PG P
Sbjct: 565 GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDP 620

Query: 406 GVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
                  GP   G  G  G RG PG  G PG  GP G  G PG   P     + G +
Sbjct: 621 -------GPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670



 Score =  124 bits (311), Expect = 4e-28
 Identities = 76/158 (48%), Positives = 84/158 (53%), Gaps = 21/158 (13%)

Query: 439 GPKGEKGDPGPEGPRGLAGEVG---NKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
           GP GE+G PGP GP G+ G  G   ++G KG  G PGP G  G  G PGK G+ G  G  
Sbjct: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85

Query: 496 GPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKG 555
           GP G  G  G KG  G PG   PG RG PG +G PGP GP G  G   L GE GR G   
Sbjct: 86  GPDGSPGSIGSKGQKGEPGV--PGSRGFPG-RGIPGPPGPPGTAG---LPGELGRVG--- 136

Query: 556 EPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
                 P G+PG RGP   PGP G PGP G  G  + D
Sbjct: 137 ------PVGDPGRRGP---PGPPGPPGPRGTIGFHDGD 165



 Score =  120 bits (302), Expect = 4e-27
 Identities = 68/146 (46%), Positives = 75/146 (51%), Gaps = 19/146 (13%)

Query: 454 GLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRP 513
           GL      +G  G++G PGP GP      PG  G  G  GD GP+G  G PGP G+PG+P
Sbjct: 17  GLCLCAAQRGPPGEQGPPGPPGP------PGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP 70

Query: 514 GFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPAD--PGPPGEPGPR-- 569
           G   PG  G PG  G  GP G  G  G  G KGEPG  G +G P    PGPPG PG    
Sbjct: 71  G--APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 128

Query: 570 -------GPRGVPGPEGEPGPPGDPG 588
                  GP G PG  G PGPPG PG
Sbjct: 129 PGELGRVGPVGDPGRRGPPGPPGPPG 154



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 37/73 (50%), Positives = 41/73 (56%), Gaps = 9/73 (12%)

Query: 521 RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGE 580
           RG PGE+G PGP GP G  G  G+ G+ G KG         PPG PGP G  G PG  G+
Sbjct: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKG---------PPGPPGPAGEPGKPGAPGK 75

Query: 581 PGPPGDPGLTECD 593
           PG PG  GLT  D
Sbjct: 76  PGTPGADGLTGPD 88


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score =  303 bits (775), Expect = 6e-82
 Identities = 183/398 (45%), Positives = 207/398 (52%), Gaps = 58/398 (14%)

Query: 243 YGECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK-- 300
           YG    V    +PGP GP G  G  G  G +  PG+PGQ+G  G P   GP GFPG K  
Sbjct: 123 YGPKGDVGPAGLPGPRGPPGPPGIPGPAG-ISVPGKPGQQGPTGAP---GPRGFPGEKGA 178

Query: 301 -GVPGFKGEKGE--FGADGRKGAPGL-----------------AGKNGTDGQ-------- 332
            GVPG  G+KGE  +GA GR G  GL                  G+NG  GQ        
Sbjct: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG 238

Query: 333 -KGKLGRIGPPGCKGDPGNRGPDGY--PGEAGSPGERGDQGGKGDPGRPGRRGPPGE--I 387
             G++G IGPPG +G PG RGP+G   PG AG+PG+ G  G KG PG PG  GPPG    
Sbjct: 239 FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF 298

Query: 388 GAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDP 447
           G  G  G +G  G  G PG  GAKG  GP G  G+PG  G PG  G  G  G  G  G P
Sbjct: 299 GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP 358

Query: 448 GPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPK 507
           GP+G  G AG  G  GAKG+RG PG  G  G  G+PG  G +G+PG  GP+GD G  GP 
Sbjct: 359 GPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPP 418

Query: 508 GDPGRPGFSYPGPRGAPGEKGEPGPRGP---EGGRGDFGLKGEPGRKGEKGEPADPGPP- 563
           G PG  G +  G +G PG  GE GPRG     G RG  G  G PG  G KG+P  PGPP 
Sbjct: 419 GLPGPVGPA--GAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG 476

Query: 564 -------------GEPGPRGPRGVPGPEGEPGPPGDPG 588
                        G PGP GPRG  G  G PGPPG PG
Sbjct: 477 PAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPG 514



 Score =  285 bits (730), Expect = 9e-77
 Identities = 177/388 (45%), Positives = 204/388 (52%), Gaps = 55/388 (14%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP-----IGFPGPKGVPGFKGEK 309
           PGP GP G RG  G  G  G+PG  G  G QG+PG+ GP     +G PG  G+PG  GE+
Sbjct: 62  PGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGER 120

Query: 310 GEFGADGRKGAPGLAGKNGTDGQKGKLGRI-----GPPGCKGDPGNRGPDGYPGEAGSPG 364
           G +G  G  G  GL G  G  G  G  G       G PG +G  G  GP G+PGE G+PG
Sbjct: 121 GPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPG 180

Query: 365 ERGDQGGKGD-----PGRPGRRGPPGEIGAKGSK-----GYQGNSGAPGSPGVKGAKGGP 414
             G  G KG+     PGRPG RG PG  G  G       G +G +G PG PG+KG +G P
Sbjct: 181 VPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFP 240

Query: 415 ------GPRGPKGEPGRR-----GDPGTKGSPGSDGPKGEKGDP------GPEGPRGLAG 457
                 GP GP+G PG R     G PG  G+PG  G  G KG P      GP GP G  G
Sbjct: 241 GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-G 299

Query: 458 EVGNKGAKGDRGL------PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG 511
           + G  G KG+RG       PG +G QG  G PGK G  G PG+ GP+G  G PG  G PG
Sbjct: 300 KPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPG 359

Query: 512 RPGFSYP-GPRGAPGEKGE---PGPRGPEGGRGDFGL---KGEPGRKGEKGEPADPGPPG 564
             G + P GP G PG KGE   PG  G  G  G  GL   KG PG  G KG+P   GPPG
Sbjct: 360 PKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG 419

Query: 565 EPGPRGP---RGVPGPEGEPGPPGDPGL 589
            PGP GP   +G+PG  GE GP G PG+
Sbjct: 420 LPGPVGPAGAKGMPGHNGEAGPRGAPGI 447



 Score =  276 bits (705), Expect = 7e-74
 Identities = 162/338 (47%), Positives = 182/338 (53%), Gaps = 35/338 (10%)

Query: 254 IPGPSGPKGYRGQKGA--KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
           +PGP GP G  G  G   +G  G PG+PG KG +G PG  GPIG PGP+G PG +G +G 
Sbjct: 204 LPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG- 262

Query: 312 FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGD-----PGNRGPDGYPGEAGSPGER 366
            G  G  GAPG  G  GT G  G  G  GPPG  G      PG +G  G  G  G PG +
Sbjct: 263 IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAK 322

Query: 367 GDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG---PGPRGPKGEP 423
           G+QG  G PG+PG  GPPG +G +G KG  G+ G PG  G  G  G    PG +G +G P
Sbjct: 323 GEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSP 382

Query: 424 GRRGDPGTKGSPGSDGPKGE------KGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQ 477
           G  G PG  G PG DGPKG       KGDPG  GP GL G VG  GAKG  G  G  GP+
Sbjct: 383 GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442

Query: 478 GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEG 537
           GA G PG +G        GP G  G PG KGDPG PG   PGP G    KG  GP GP  
Sbjct: 443 GAPGIPGTRGP------IGPPGIPGFPGSKGDPGSPG--PPGPAGI-ATKGLNGPTGP-- 491

Query: 538 GRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVP 575
                   G PG +G  GEP  PGPPG PGP G   +P
Sbjct: 492 -------PGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP 522



 Score =  251 bits (642), Expect = 1e-66
 Identities = 146/319 (45%), Positives = 172/319 (53%), Gaps = 28/319 (8%)

Query: 290 IEGPIGFPGPKGVPGFKGEKGEFGADGRK--GAPGLAGKNGTDGQKG--KLGRIGPPGCK 345
           + G  G PGP G  G +G  G  G  G+   G+PGL G+ G  G  G   +G+ G PG  
Sbjct: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114

Query: 346 GDPGNRGPDGYPGE---AGSPGERGDQGGKGDPGR-----PGRRGPPGEIGAKGSKGYQG 397
           G PG RGP G  G+   AG PG RG  G  G PG      PG+ G  G  GA G +G+ G
Sbjct: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174

Query: 398 NSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP--------KGEKGDPGP 449
             GAPG PG+ G KG  G  G  G PG RG PG +G  G  GP         G  G PG 
Sbjct: 175 EKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGI 233

Query: 450 EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGD 509
           +G RG  GE+G  G  G +G PG RGP+G +G+PG  G+ G PG  G +G  G PG  G 
Sbjct: 234 KGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGP 292

Query: 510 PGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPR 569
           PG PGF  P   G PG KGE GP G  GG    G KGE G  G  G+P   GPPG  GP+
Sbjct: 293 PGPPGFGKP---GLPGLKGERGPAGLPGGP---GAKGEQGPAGLPGKPGLTGPPGNMGPQ 346

Query: 570 GPRGVPGPEGEPGPPGDPG 588
           GP+G+PG  G PGP G+ G
Sbjct: 347 GPKGIPGSHGLPGPKGETG 365



 Score =  187 bits (475), Expect = 3e-47
 Identities = 117/267 (43%), Positives = 137/267 (51%), Gaps = 34/267 (12%)

Query: 341 PPGCKGD-PGNRGPDGYPGEAGSPG--ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQG 397
           P G KG  P  +     P    S G   RG+QG  G PG  G RG PG  G  G  GY  
Sbjct: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-- 85

Query: 398 NSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
                GSPG++G  G PGP GP    G+ G PG  G PG  GP G KGD GP      AG
Sbjct: 86  -----GSPGLQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGP------AG 133

Query: 458 EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSY 517
             G +G  G  G+PGP G     G+PG+QG  G PG  G  G+ G PG  G  G+ G   
Sbjct: 134 LPGPRGPPGPPGIPGPAGIS-VPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG 192

Query: 518 PGPRGAPGEKGEPGPRGPEGG--------RGDFGLKGEPGRKGEKGEPAD------PGPP 563
            G  G PGE+G PGP+GP G         RG+ G+ G+PG KG++G P +      PGP 
Sbjct: 193 YGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQ 252

Query: 564 GEPGPRGPRGV--PGPEGEPGPPGDPG 588
           G PG RGP G+  PG  G PG PG PG
Sbjct: 253 GPPGERGPEGIGKPGAAGAPGQPGIPG 279



 Score =  134 bits (336), Expect = 5e-31
 Identities = 77/165 (46%), Positives = 88/165 (53%), Gaps = 14/165 (8%)

Query: 430 GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSR 489
           G +G+PG  GP G +G PGP GP G  G  G+ G +G+ GLPGP GP  A+G+PG  G  
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPS-AVGKPGVPGLP 114

Query: 490 GDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPE--GGRGDFGLKGE 547
           G PG+ GP G  G  GP G         PGPRG PG  G PGP G    G  G  G  G 
Sbjct: 115 GKPGERGPYGPKGDVGPAG--------LPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGA 166

Query: 548 PGRKGEKGEPADPGPPGEPGPRGPRG--VPGPEGEPGPPGDPGLT 590
           PG +G  GE   PG PG  G +G  G   PG  GE G PG  G T
Sbjct: 167 PGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPT 211


>gi|183583553 collagen, type XXIX, alpha 1 [Homo sapiens]
          Length = 2526

 Score =  302 bits (773), Expect = 1e-81
 Identities = 189/550 (34%), Positives = 272/550 (49%), Gaps = 44/550 (8%)

Query: 147  QDRSKGTVHFAVVITDGHVTGSPCGGIKLQAERAREEGIRLFAVAPNQNLKEQGLRDIAS 206
            +D+S       ++ +DG  + S    ++ Q++R RE G+    V             + +
Sbjct: 1295 KDKSASRGQVLLIFSDGLQSESNIM-LENQSDRLREAGLDALLVV-----------SLNT 1342

Query: 207  TPHELY-------RNDYATMLPDSTEIDQDTINRIIKVMKHEAYGECYKVSCLEIPGPSG 259
            T H  +       R DY T L       ++   ++ + + + A   C    C + PG  G
Sbjct: 1343 TAHHEFSSFEFGKRFDYRTHLTIGM---RELGKKLSQYLGNIAERTCCCTFC-KCPGIPG 1398

Query: 260  PKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKG 319
            P G RG +  KG+ G  G  G +G  G+PG+ G  G  G KG+ G  G  G+ G  G  G
Sbjct: 1399 PHGTRGLQAMKGSQGLKGSRGHRGEDGNPGVRGDTGPQGDKGIAGCPGAWGQKGLKGFSG 1458

Query: 320  APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPG 379
              G  G +G DG  G+ G  G PG KG+ G+ G  G PG  G+PG+ G++G  GDPG PG
Sbjct: 1459 PKGGHGDDGIDGLDGEEGCHGFPGIKGEKGDPGSQGSPGSRGAPGQYGEKGFPGDPGNPG 1518

Query: 380  RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439
            +         KG KG +G  G  G  G KG +G P  RG +G  G+RG  G  G PG+ G
Sbjct: 1519 QNN-----NIKGQKGSKGEQGRQGRSGQKGVQGSPSSRGSRGREGQRGLRGVSGEPGNPG 1573

Query: 440  PKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPG---------KQGSRG 490
            P G  G  G +GP+G  G  G KG KG +G  GP+G  G +G  G         K+G  G
Sbjct: 1574 PTGTLGAEGLQGPQGSQGNPGRKGEKGSQGQKGPQGSPGLMGAKGSTGRPGLLGKKGEPG 1633

Query: 491  DPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR 550
             PGD GP G +GQ G +GD G PG+   G +G  G +G PG  G +G  G+ G+ G PG 
Sbjct: 1634 LPGDLGPVGQTGQRGRQGDSGIPGYGQMGRKGVKGPRGFPGDAGQKGDIGNPGIPGGPGP 1693

Query: 551  KGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECDVMTYVRETCGCCDCEKR 610
            KG +G     G  GE G RG  G PG  G  G  G P  ++CD++ ++RE   C   +++
Sbjct: 1694 KGFRGLALTVGLKGEEGSRGLPGPPGQRGIKGMAGQPVYSQCDLIRFLREHSPC--WKEK 1751

Query: 611  CGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHE 668
            C A   ++VF +D+S  +   +F   ++ + ++VN L    ++     G RV +V Y + 
Sbjct: 1752 CPAYPTELVFALDNSYDVTEESFNKTRDIITSIVNDLN--IRENNCPVGARVAMVSY-NS 1808

Query: 669  GTFEAIQLDD 678
            GT   I+  D
Sbjct: 1809 GTSYLIRWSD 1818



 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 55/165 (33%), Positives = 83/165 (50%), Gaps = 17/165 (10%)

Query: 598 VRETCGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETG 657
           VRE C    CE      D++F++DSS SIG  NF   K F+ N++ ++  I  D      
Sbjct: 613 VREICAEKGCEDM--KADIMFLVDSSWSIGNENFRKMKIFMKNLLTKI-QIGADK----- 664

Query: 658 TRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLI-K 716
           T++GVVQ+S + T E  QL+  R  +     +A+  +  I  GT T  AL F        
Sbjct: 665 TQIGVVQFS-DKTKEEFQLN--RYFTQQEISDAIDRMSLINEGTLTGKALNFVGQYFTHS 721

Query: 717 ESRRQKTRVFAVVITDG--RHDPRDDDLNLRALCDRDVTVTAIGI 759
           +  R   + F ++ITDG  + D RD     R L  +DVT+ ++G+
Sbjct: 722 KGARLGAKKFLILITDGVAQDDVRDP---ARILRGKDVTIFSVGV 763



 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 54/164 (32%), Positives = 80/164 (48%), Gaps = 24/164 (14%)

Query: 603 GCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGV 662
           GC D ++     D+ F+ID S SI    F   K F++  V  + +I  D       RVGV
Sbjct: 434 GCVDTKEA----DIHFLIDGSSSIQEKQFEQIKRFMLE-VTEMFSIGPDK-----VRVGV 483

Query: 663 VQYSHEGTFEAIQLD-DERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIK---ES 718
           VQYS +   E    D    ID     ++A+ N++ + GGT+T  AL +   ++IK   + 
Sbjct: 484 VQYSDDTEVEFYITDYSNDID----LRKAIFNIKQLTGGTYTGKALDYIL-QIIKNGMKD 538

Query: 719 RRQKTRVFAVVITDGRHDPR--DDDLNLRALCDRDVTVTAIGIG 760
           R  K   + +V+TDG    R  +    LRA     +TV A+GIG
Sbjct: 539 RMSKVPCYLIVLTDGMSTDRVVEPAKRLRA---EQITVHAVGIG 579



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 63/223 (28%), Positives = 100/223 (44%), Gaps = 35/223 (15%)

Query: 602 CGCCDCEKRCGALDVVFVIDSSESIGYTNFTLEKNFVINVVN-RLGAIAKDPKSETGTRV 660
           C   DC KR   LDVVFV+D S SI       +K +  +++N  +  + K        + 
Sbjct: 802 CALHDC-KRITLLDVVFVLDHSGSI-------KKQYQDHMINLTIHLVKKADVGRDRVQF 853

Query: 661 GVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKE--S 718
           G ++YS +     I        + S+  E ++      G T+T  ALK A     +E  S
Sbjct: 854 GALKYSDQPN---ILFYLNTYSNRSAIIENLRKRRDTGGNTYTAKALKHANALFTEEHGS 910

Query: 719 R-RQKTRVFAVVITDGR-HDPRDDDLNLRA--LCDRDVTVTAIGIGDMFHEKHESENLYS 774
           R +Q  +   +VITDG  HD   D LN  A  L ++ +T+ A+G+G     K   + L  
Sbjct: 911 RIKQNVKQMLIVITDGESHD--HDQLNDTALELRNKGITIFAVGVG-----KANQKELEG 963

Query: 775 IACDKPQQVRNMTLFSDLVAEKFIDDMEDVLCPDPQIVCPDLP 817
           +A +K     N T++ D       D ++DV     + +C + P
Sbjct: 964 MAGNK-----NNTIYVD-----NFDKLKDVFTLVQERMCTEAP 996



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 44/176 (25%), Positives = 78/176 (44%), Gaps = 13/176 (7%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEG---- 669
            +DV F+ID+S+ +G   F   K F+ +V++          S  G RV V+ YS  G    
Sbjct: 2290 MDVAFLIDASQRVGSDEFKEVKAFITSVLDYFHIAPTPLTSTLGDRVAVLSYSPPGYMPN 2349

Query: 670  TFEA---IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFAYDRLIKESRRQKTRVF 726
            T E    ++ D    +S+   K  +++ + + G  +   AL++  D +   +   +    
Sbjct: 2350 TEECPVYLEFDLVTYNSIHQMKHHLQDSQQLNGDVFIGHALQWTIDNVFVGTPNLRKNKV 2409

Query: 727  AVVITDGRHDPRDDD----LNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD 778
              VI+ G  +  D D    ++LRA C +  ++     G   ++K E E L S   D
Sbjct: 2410 IFVISAGETNSLDKDVLRNVSLRAKC-QGYSIFVFSFGPKHNDK-ELEELASHPLD 2463



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 55/218 (25%), Positives = 96/218 (44%), Gaps = 30/218 (13%)

Query: 615 DVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPKSETGTRVGVVQYSHEGTFE-A 673
           DVVF++DSS+ +G  +F   K F+  ++N L      P      RV + QYS E   E  
Sbjct: 30  DVVFLVDSSDHLGPKSFPFVKTFINKMINSL------PIEANKYRVALAQYSDEFHSEFH 83

Query: 674 IQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA----YDRLIKESRRQKTRVFAVV 729
           +     R   L+  K   KN ++I G      AL+ A    +   I    R++     VV
Sbjct: 84  LSTFKGRSPMLNHLK---KNFQFIGGSLQIGKALQEAHRTYFSAPINGRDRKQFPPILVV 140

Query: 730 ITDGRHDPRDDDLNLRALCDRDVTVTAIGIGDMFHEKHESENLYSIACD----KPQQVRN 785
           +     +   ++ + +AL    V + ++G+     +K   ENL ++A        + +R+
Sbjct: 141 LASAESEDEVEEAS-KALQKDGVKIISVGV-----QKASEENLKAMATSHFHFNLRTIRD 194

Query: 786 MTLFSDLVAEKFIDDM----EDVLCPDPQIVCPDLPCQ 819
           ++ FS  + +  I D+    E  +  D Q+  P + CQ
Sbjct: 195 LSTFSQNMTQ-IIKDVTKYKEGAVDADMQVHFP-ISCQ 230



 Score = 38.5 bits (88), Expect = 0.026
 Identities = 45/178 (25%), Positives = 79/178 (44%), Gaps = 17/178 (9%)

Query: 614  LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAKDPK-SETGTRVGVVQYS------ 666
            +DVVF+ID+S +I    F   K  V +V++    IA DP  S++G R+ ++ YS      
Sbjct: 1962 MDVVFLIDNSRNIAKDEFKAVKALVSSVIDNFN-IASDPLISDSGDRIALLSYSPWESSR 2020

Query: 667  -HEGTFEAIQLDDERIDSLSSFKEAVK-NLEWIAGGTWTPSALKFAYDRLIKESRRQKTR 724
               GT +  + D    D+    K  ++ + + + G      AL +  + L  E+   +  
Sbjct: 2021 RKMGTVKT-EFDFITYDNQLLMKNHIQTSFQQLNGEATIGRALLWTTENLFPETPYLRKH 2079

Query: 725  VFAVVITDGRHDPRDDDLN---LRALCDRDVTVTAIGIGDMFHEKHESENLYSIACDK 779
                V++ G +  R + +    LRA C +   +  I +G     K + E L S   D+
Sbjct: 2080 KVIFVVSAGENYERKEFVKMMALRAKC-QGYVIFVISLGST--RKDDMEELASYPLDQ 2134



 Score = 37.7 bits (86), Expect = 0.044
 Identities = 44/179 (24%), Positives = 86/179 (48%), Gaps = 18/179 (10%)

Query: 593  DVMTYVRETCGCCDCEKRCGA--LDVVFVIDSSESIGYTNFTLEKNFVINVVNRLGAIAK 650
            DV T V+E   C +  + C     DV+F+ D S+ +  ++F     F+ ++++       
Sbjct: 982  DVFTLVQERM-CTEAPEVCHLQEADVIFLCDGSDRVSNSDFVTMTTFLSDLIDNF----- 1035

Query: 651  DPKSETGTRVGVVQYSHEGTFEAIQLDDERIDSLSSFKEAVKNLEWIAGGTWTPSALKFA 710
            D +S+   ++G+ Q+     +++I ++ +   + + +K  ++N+    G      ALK  
Sbjct: 1036 DIQSQR-MKIGMAQFG--SNYQSI-IELKNSLTKTQWKTQIQNVSKSGGFPRIDFALKKV 1091

Query: 711  YDRL-IKESRRQKTRV--FAVVITDGRHDPRDDDLN-LRALCDRDVTVTAIGIGDMFHE 765
             +   +    R+   V    VVIT G  DPR D  + ++ L D  + V  +GIGD++ E
Sbjct: 1092 SNMFNLHAGGRRNAGVPQTLVVITSG--DPRYDVADAVKTLKDLGICVLVLGIGDVYKE 1148


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  301 bits (772), Expect = 1e-81
 Identities = 168/355 (47%), Positives = 188/355 (52%), Gaps = 33/355 (9%)

Query: 261  KGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGA 320
            +G  G  G+ G  G PG PGQ+G +G PG+ G  G PGP G PGF G      A G  G 
Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPG------AVGSPGL 1064

Query: 321  PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGR 380
            PGL G+ G  G  G  G  GPPG  G PG  GP G PG  G  G  G  G KG+PG PG 
Sbjct: 1065 PGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGS 1124

Query: 381  RG---PPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGT------ 431
             G   PPG  G +G +G QGNSG  G  G +G  G PGP GP G PG+ G PG       
Sbjct: 1125 EGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184

Query: 432  KGSPGSDGPKGEKGDPGPEGPRGLAGEV------GNKGAKGDRGLPGPRGPQGALGEPGK 485
            KGS G  GP G  G PGP GP G+ G        G  G  G RG PGP GP G +G PG 
Sbjct: 1185 KGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGF 1244

Query: 486  QGSRGDPGDAGPRGDSGQPGPKGDPGRPGF----SYPGPRGAPGEKGEPGPRGPEG---- 537
            +G  G PG  GP+GD G+PGP G  GRPG        GP+G PG  G  GP GP G    
Sbjct: 1245 KGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGP 1304

Query: 538  -GRGDFGLKGEPGRKGEK---GEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G    GLKG+ G  GE+   G P  PGPPG PGP G  G  G  G+ GPPG  G
Sbjct: 1305 AGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQG 1359



 Score =  295 bits (754), Expect = 2e-79
 Identities = 163/342 (47%), Positives = 185/342 (54%), Gaps = 12/342 (3%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP---IGFPGPKGVPGFKGEKGEF 312
            G  GP G RG  G  G +G PG PG  G  G PG++G     G  G KG PG  G+ G  
Sbjct: 1033 GEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYP 1092

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG---SPGERGDQ 369
            GA G  G PG+ G+ G  G  G+ G  GPPG +G PG  GP G  GE G   + GE+GDQ
Sbjct: 1093 GATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQ 1152

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP 429
            G +G PG PG  GPPG  G  GS G  G     GS G++G  G PG  GP G PG +G  
Sbjct: 1153 GFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPA 1212

Query: 430  GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEP---GKQ 486
            G  G  G DG  G +GDPGP GP GL G  G KG  G  GLPGP+G  G  G P   G+ 
Sbjct: 1213 GLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRP 1272

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKG 546
            G+ G+PG  GP+G  G PG  G PG PG   PGP G     G  G RG  G RG  GL G
Sbjct: 1273 GAEGEPGAMGPQGRPGPPGHVGPPGPPG--QPGPAGI-SAVGLKGDRGATGERGLAGLPG 1329

Query: 547  EPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            +PG  G  G P +PG  G  G  GP G  G  G PGP GDPG
Sbjct: 1330 QPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPG 1371



 Score =  288 bits (737), Expect = 1e-77
 Identities = 165/375 (44%), Positives = 195/375 (52%), Gaps = 46/375 (12%)

Query: 255  PGPSGPKGY------------RGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV 302
            PGP GP G+            +G++G  G  G+ GEPG  G+ G PG  GP G PG KG 
Sbjct: 1047 PGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGE 1106

Query: 303  PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGD---------PGNRGP 353
             G+ G  GE G  G  G+ GL G  G  G +G+ G  G  G KGD         PG  GP
Sbjct: 1107 RGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGP 1166

Query: 354  DGYPGEAGSPG------ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGV 407
             G+PG+ GSPG      E+G +G +G  G PG  GPPG  G +G  G  G  G  G PG+
Sbjct: 1167 PGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGL 1226

Query: 408  KGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD 467
               +G PGP GP G  G  G  G  G PG  GPKG+ G PGP G  G  G  G  GA G 
Sbjct: 1227 ---RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGP 1283

Query: 468  RGLPGPRGPQGALGEPGK-----------QGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS 516
            +G PGP G  G  G PG+           +G RG  G+ G  G  GQPGP G PG PG  
Sbjct: 1284 QGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPG-- 1341

Query: 517  YPGPRGAPGEKGEPGPR---GPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRG 573
             PG  GA G++G PG +   GP G +GD G  G+ G+ GEKG    PG PG+ G  GP G
Sbjct: 1342 EPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVG 1401

Query: 574  VPGPEGEPGPPGDPG 588
             PGP GE G PG PG
Sbjct: 1402 PPGPAGERGHPGAPG 1416



 Score =  281 bits (720), Expect = 1e-75
 Identities = 159/347 (45%), Positives = 184/347 (53%), Gaps = 23/347 (6%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG +GP G  G KG +G  G  GE G+ G  G  G+ GP G  GP+G  G +G  GE G 
Sbjct: 1092 PGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGD 1151

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGC---KGDPGNRGPDGYPGEAGSPGERGDQGG 371
             G +G PG  G  G  G  GK+G  GPPG    KG  G RGP G PG  G PG  G QG 
Sbjct: 1152 QGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGP 1211

Query: 372  KG------DPGRPGRRGPPGEIGAKG---SKGYQGNSGAPGSPGVKGAKGGPGPRGPKGE 422
             G        G+PG RG PG  G  G     G++G +G PG PG KG  G PGP G  G 
Sbjct: 1212 AGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGR 1271

Query: 423  PGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE 482
            PG  G+PG  G  G  GP G  G PGP G  G AG +   G KGDRG  G RG  G  G+
Sbjct: 1272 PGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAG-ISAVGLKGDRGATGERGLAGLPGQ 1330

Query: 483  PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-SYPGPRGAPGEKGEPGPRGPEGGRGD 541
            PG  G  G PG+ G  G +G+ GP   PG+ GF   PGP+G PG  G+   +G  G +G 
Sbjct: 1331 PGPPGHPGPPGEPGTDGAAGKEGP---PGKQGFYGPPGPKGDPGAAGQ---KGQAGEKGR 1384

Query: 542  FGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G+ G PG+ G  G     GPPG  G RG  G PGP G PG PG PG
Sbjct: 1385 AGMPGGPGKSGSMG---PVGPPGPAGERGHPGAPGPSGSPGLPGVPG 1428



 Score =  272 bits (695), Expect = 1e-72
 Identities = 170/457 (37%), Positives = 205/457 (44%), Gaps = 118/457 (25%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PGP GP G RG++G +GN GE G+ G +G+ G PG  GP GFPG  G PG  G + E G
Sbjct: 1127 LPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKG 1186

Query: 314  ADGRKGAPGL---------------AGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPG 358
            ++G +G  GL               AG +G DG+ GK G  G PG  G PG  GP G+ G
Sbjct: 1187 SEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKG 1246

Query: 359  EAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG 418
            + G PG  G +G  G PG PG  G PG  G  G+ G QG  G PG  G  G  G PGP G
Sbjct: 1247 KTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAG 1306

Query: 419  --------------------------PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP 452
                                      P G PG  G+PGT G+ G +GP G++G  GP GP
Sbjct: 1307 ISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGP 1366

Query: 453  RGLAGEVGNKGAKGDRGL------PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGP 506
            +G  G  G KG  G++G       PG  G  G +G PG  G RG PG  GP G  G PG 
Sbjct: 1367 KGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGV 1426

Query: 507  KGD------------------------------------------PGRPG----FSYPGP 520
             G                                           PGRPG       PG 
Sbjct: 1427 PGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGR 1486

Query: 521  RGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGE-----------PADPGPPGEPG-- 567
             GAPG  G PG  G EG +G  G++G PG KGEKG+           P  PGP G PG  
Sbjct: 1487 PGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYG 1546

Query: 568  ------PRGPRGVPG------PEGEPGPPGDPGLTEC 592
                  P G +G+PG      P G+PG  G    ++C
Sbjct: 1547 KMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDC 1583



 Score =  268 bits (685), Expect = 2e-71
 Identities = 167/398 (41%), Positives = 190/398 (47%), Gaps = 61/398 (15%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPI-------GFPGPKGVPGFK 306
            IPGP GP G  G +G  GN G PG+PG     G   IE  +          G +  PG+ 
Sbjct: 911  IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYL 970

Query: 307  GEKGEFGADGRKGAPGL-----------------AGKNGTDGQKGKLGRIGPPGCKGDPG 349
             EKGE G  G  G PGL                 A  + ++G  G +G  G PG  G PG
Sbjct: 971  VEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPG 1030

Query: 350  NRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPG---EIGAKGSKGYQGNSGAPGSPG 406
             RG +G PG  GSPG  G  G  G PG  G  G PG   E G  G  G +G  G PG PG
Sbjct: 1031 QRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPG 1090

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
              GA G PG  G KGE G  G  G KG PG  G +G  G PGP GPRG  G  GN G KG
Sbjct: 1091 YPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKG 1150

Query: 467  DRGL---------PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSY 517
            D+G          PGP G  G +G PG  G + + G  G RG SG PG  G PG PG   
Sbjct: 1151 DQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQG 1210

Query: 518  P-------GPRGAPGEKGEPGPRGPEGGRGDFGLKGE---PGRKGEKGEPADPGPPG--- 564
            P       G  G PG +G+PGP GP G  G  G KG+   PG  G KG+   PGPPG   
Sbjct: 1211 PAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTG 1270

Query: 565  ------EPGPRGPRGVPGPEGE------PGPPGDPGLT 590
                  EPG  GP+G PGP G       PG PG  G++
Sbjct: 1271 RPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGIS 1308



 Score =  259 bits (663), Expect = 5e-69
 Identities = 186/501 (37%), Positives = 222/501 (44%), Gaps = 128/501 (25%)

Query: 210 ELYRNDYATMLPDSTEIDQDTINRI-------IKVMKHEAYGECYKVSCLE-------IP 255
           ++Y   +    P ++E+D     RI        KV +  A  EC    C+          
Sbjct: 273 KVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADEC--PPCVHGARDSNVTL 330

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGR--------------QGDPGIEGPIGFPGPKG 301
            PSGPKG +G++G  G  G  GE G +G               +G  G +G  G  GP G
Sbjct: 331 APSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSG 390

Query: 302 VPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAG 361
           +PG  GEKG+ G  G  G  G+ GK G DG+ G++  IGP G KGDPG  GP+G  GE G
Sbjct: 391 LPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPG 450

Query: 362 SPGERGDQGG--KGDPGRPGRRGPPGEIGAKGSKGY---QGNSGAPGSPGVKGAKGGP-- 414
            PG  G  G    G PG PG  GPPG  G KGS G    +G  G PG PGVKG KG P  
Sbjct: 451 PPGLPGPPGIGLPGTPGDPG--GPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCE 508

Query: 415 ----------------GPRGPKGEPGRRGDP-GTKGSPGSDGPKGEKGDP--------GP 449
                           G  GPKGEPG   DP   +G PG  G KGEKG+P        G 
Sbjct: 509 VCPTLPEGFQNFVGLPGKPGPKGEPG---DPVPARGDPGIQGIKGEKGEPCLSCSSVVGA 565

Query: 450 E---GPRGLAGEVGNKG-----AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS 501
           +      G +G+VG+ G       G  G+PG +G +G  GE G  GS G PG  GP G  
Sbjct: 566 QHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIK 625

Query: 502 GQ------------------------PGP---KGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
           G                         PGP   KG+PG PGF  PG +G  GE+G  G +G
Sbjct: 626 GAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKG 685

Query: 535 PEGGRGDFGLKGEPGRKGEKGEPADPGP------------------------PGEPGPRG 570
             G  GD G  G  GR G  GEP   GP                         G PG  G
Sbjct: 686 DAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPG 745

Query: 571 PRGVPGPE--GEPGPPGDPGL 589
           P+G  GPE  G PG PG PGL
Sbjct: 746 PKGEQGPEGVGRPGKPGQPGL 766



 Score =  254 bits (650), Expect = 2e-67
 Identities = 169/458 (36%), Positives = 196/458 (42%), Gaps = 119/458 (25%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQ-----KGRQGDPGIEGPIGFPGPKGVPGFKGEK 309
            PG  G  G +G  G KG  GEPG PG+     +G  G PG+ G  G PGP+G PG  GEK
Sbjct: 761  PGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEK 820

Query: 310  GEFGADGRKGAPG--------LAGKNGTDGQKGKLGRIGPPGCKG--------------- 346
            G  G+ G KGA G        ++G  G DGQ+G+ G  G PG KG               
Sbjct: 821  GAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPS 880

Query: 347  ---------------------DPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPG 385
                                  PG +GP G PG  G PG  G QG  G+ G PG+ G   
Sbjct: 881  QGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTA 940

Query: 386  EIGA----------------------------KGSKGYQGNSGAPG-------------- 403
            E+G+                            KG KG QG  G PG              
Sbjct: 941  ELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERP 1000

Query: 404  ------------SPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEG 451
                         PG  G+ G PGP G  G+ G  G PG +GSPG  GP G  G PG  G
Sbjct: 1001 RAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVG 1060

Query: 452  PRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPG 511
              GL G  G +G  G  G  G  GP G  G PG  G  G PG  G RG +G  G KG+PG
Sbjct: 1061 SPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPG 1120

Query: 512  RPGFS-YPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRG 570
             PG    PGP G  G +GE GP+G  G +GD G +G+PG  G  G P  PG  G PGP G
Sbjct: 1121 PPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPG 1180

Query: 571  PR---------------GVPGPEGEPGPPGDPGLTECD 593
            P+               G PGP G PG  G  GL   D
Sbjct: 1181 PQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLD 1218



 Score =  250 bits (639), Expect = 3e-66
 Identities = 167/392 (42%), Positives = 194/392 (49%), Gaps = 62/392 (15%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  GPKG +G +G  G  G+PG+PG  G QG PG++G  G PGP G  G +G +GE GA
Sbjct: 741  PGQPGPKGEQGPEGV-GRPGKPGQPGLPGVQGPPGLKGVQGEPGPPG-RGVQGPQGEPGA 798

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G  GL G  G  G  G+ G  G PG KG  G  GP G    +G PG  G QG  G 
Sbjct: 799  PGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG-ASVSGPPGRDGQQGQTGL 857

Query: 375  PGRPGRRGPPGEIGAKG-----SKG---YQGNSGAPG-------SPGVKGAKGGPGPRGP 419
             G PG +GP GE G  G     S+G   + G  GAPG        PG +G  G PGP GP
Sbjct: 858  RGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGP 917

Query: 420  KGEPGRRGDPGTKGSPGSDGPKGEKGDPGPE-------------GPRGLAGEVGNKGAKG 466
             G PG +G PG  G PG  G   E G    E             G R   G +  KG KG
Sbjct: 918  PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977

Query: 467  DRGLPG----------------PRGPQG----ALGEPGKQGSRGDPGDAG---PRGDSGQ 503
            D+G+PG                PR  +     + G+PG  GS G PG  G    RG+ G 
Sbjct: 978  DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037

Query: 504  PGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGL---KGEPGRKGEKGEPADP 560
            PG +G PG PG    GP G PG  G PG  G +G RG  GL   KGEPG  G+ G P   
Sbjct: 1038 PGMRGSPGPPGPI--GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGAT 1095

Query: 561  GPPGEPGPRGPRGVPGP---EGEPGPPGDPGL 589
            GPPG PG +G RG  G    +GEPGPPG  GL
Sbjct: 1096 GPPGLPGIKGERGYTGSAGEKGEPGPPGSEGL 1127



 Score =  244 bits (624), Expect = 2e-64
 Identities = 177/488 (36%), Positives = 214/488 (43%), Gaps = 149/488 (30%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQ------------KGRQGDPGIEGP-------- 293
           +PG +G KG +G+KG  G  G PG+PG+            KG++GDPG  GP        
Sbjct: 391 LPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPG 450

Query: 294 ---------IGFPG----PKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGK----- 335
                    IG PG    P G PG KG+KG  G  G++G  G  GK G  G+KG      
Sbjct: 451 PPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVC 510

Query: 336 ----------LGRIGPPGCKGDPGNRGP-------DGYPGEAGSP--------------- 363
                     +G  G PG KG+PG+  P        G  GE G P               
Sbjct: 511 PTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVS 570

Query: 364 --GERGDQG--GKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPG------VKGAKGG 413
             G  GD G  G G PG PGR G PG  G KG+ G  G +G+PG PG      +KGAKG 
Sbjct: 571 STGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGE 630

Query: 414 P---------------------GPRGPKGEPGRRGD--PGTKGSPGSDGPKGEKGDPGPE 450
           P                     GP G KGEPG  G   PG +G  G  G KG+KGD G  
Sbjct: 631 PCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNP 690

Query: 451 GPRGLAGEVGNKGAKGDRGLPGPRGPQGALGE-----PGKQGS----RGDPGDAGPRGDS 501
           G  G  G  G  G  G+ G+ GP GP+G  G+     P  QG+     G PG  GP+G+ 
Sbjct: 691 GDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQ 750

Query: 502 G-----------QPG------------PKGDPGRPGFSYPGPRGAPGE------KGEPGP 532
           G           QPG             +G+PG PG    GP+G PG       +G PGP
Sbjct: 751 GPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGP 810

Query: 533 RGPEGGRGDFGLKGEPGRKGEKGEPADP-----GPPGEPGPRGP---RGVPGPEGEPGPP 584
           RGP G  G+ G +G PG KG  G    P     GPPG  G +G    RG PG +G  G  
Sbjct: 811 RGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEK 870

Query: 585 GDPGLTEC 592
           G+PG   C
Sbjct: 871 GEPGECSC 878



 Score =  223 bits (569), Expect = 4e-58
 Identities = 166/460 (36%), Positives = 208/460 (45%), Gaps = 106/460 (23%)

Query: 221 PDSTEIDQDTINRIIKVMKHEAYGECY-KVSCLEIP----------GPSGPKGYRGQKGA 269
           P++++  +DT +  +  +  ++ G+ Y +  CLE P          G    K  RG K  
Sbjct: 249 PETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTGRISQKAERGAKVH 308

Query: 270 KGNMGEPGEPGQKGRQ---------GDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGA 320
           +    +   P   G +         G  G +G  G PGP   PG KGEKG  G D  + +
Sbjct: 309 QETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGP---PGSKGEKGARGNDCVRIS 365

Query: 321 PG--LAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRP 378
           P   L    G  G+KG+ G +GP G  G  G         E G  GE+GD G KG PG+P
Sbjct: 366 PDAPLQCAEGPKGEKGESGALGPSGLPGSTG---------EKGQKGEKGDGGIKGVPGKP 416

Query: 379 GRRGPPGEI------GAKGSKGYQGNSGAPGSPGVKGAKGGPG------PRGPKGEPGRR 426
           GR G PGEI      G KG  G+ G  G  G PG  G  G PG      P  P G PG +
Sbjct: 417 GRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPK 476

Query: 427 GDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVG---NKGAKGDRGLPGPRGPQGALGEP 483
           GD G+ G PG +GP G+ G PG +G +G   EV     +G +   GLPG  GP+G  G+P
Sbjct: 477 GDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDP 536

Query: 484 GKQGSRGDPGDAGPRGDSGQP-----------------GPKGDPGRPGF---SYPGPRGA 523
               +RGDPG  G +G+ G+P                 G  GD G PGF     PG  G 
Sbjct: 537 --VPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGV 594

Query: 524 PGEKGE------------PGPRGPEGGRGDFGLKGE---------------------PGR 550
           PG KGE            PGP GP G  G  G KGE                     PG 
Sbjct: 595 PGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGP 654

Query: 551 KGEKGEPADP--GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            GEKGEP  P  G PG+ G  G RG+ G +G+ G PGDPG
Sbjct: 655 SGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPG 694



 Score =  197 bits (502), Expect = 3e-50
 Identities = 127/325 (39%), Positives = 147/325 (45%), Gaps = 52/325 (16%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVP 303
            G+C K       G  G +G  G  G +G  G PG  G  G  G PG  G I   G KG  
Sbjct: 1258 GDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAG-ISAVGLKGDR 1316

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSP 363
            G  GE+G  G  G+ G PG  G  G  G  G  G+ GPPG +G  G  GP G PG AG  
Sbjct: 1317 GATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQK 1376

Query: 364  GERGDQGGKGDPGRPGRR------GPPGEIGAKGSKGYQGNSGAPGSPGVKG-------- 409
            G+ G++G  G PG PG+       GPPG  G +G  G  G SG+PG PGV G        
Sbjct: 1377 GQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNY 1436

Query: 410  ----------------------------------AKGGPGPRGPKGEPGRRGDPGTKGSP 435
                                              A G PGP G  G PGR G PG+ G P
Sbjct: 1437 DEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLP 1496

Query: 436  GSDGPKGEKGDPGPEGPRGLAGEVGN--KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
            G  G +G +G PG  G  G  GE G+   G  G+ GLPGP GPQG  G  GK G+ G  G
Sbjct: 1497 GQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGY-GKMGATGPMG 1555

Query: 494  DAGPRGDSGQPGPKGDPGRPGFSYP 518
              G  G  G PGP G PG+ G   P
Sbjct: 1556 QQGIPGIPGPPGPMGQPGKAGHCNP 1580



 Score =  146 bits (369), Expect = 7e-35
 Identities = 99/269 (36%), Positives = 112/269 (41%), Gaps = 70/269 (26%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKG---RQGDPGIEGPIGFPGPKGVPGFKGEKGEF 312
            G  G  G  GQ G  G+ G PGEPG  G   ++G PG +G  G PGPKG PG  G+KG+ 
Sbjct: 1320 GERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQA 1379

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ--- 369
            G  GR G PG  GK+G+    G +G  GP G +G PG  GP G PG  G PG  GD    
Sbjct: 1380 GEKGRAGMPGGPGKSGS---MGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNY 1436

Query: 370  ------------------------------------------GGKGDPGRPGRRGPPGEI 387
                                                      G  G PGRPG  G PG  
Sbjct: 1437 DEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLP 1496

Query: 388  GAKGSKGYQGNSGAPGSPGVKGAKGG-----------PGPRGPKGEPGR--------RGD 428
            G  G +G QG  G  G PG KG KG            PGP GP+G PG          G 
Sbjct: 1497 GQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGATGPMGQ 1556

Query: 429  PGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
             G  G PG  GP G+ G  G   P    G
Sbjct: 1557 QGIPGIPGPPGPMGQPGKAGHCNPSDCFG 1585



 Score =  103 bits (258), Expect = 5e-22
 Identities = 73/206 (35%), Positives = 84/206 (40%), Gaps = 54/206 (26%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD---------------------------- 287
            GP GP G RG  GA G  G PG PG  G  GD                            
Sbjct: 1401 GPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTS 1460

Query: 288  --------------PGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQK 333
                          PG  G  G PG  G PG  G  G+ G +GR+G PG+ G  GT G+K
Sbjct: 1461 RMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEK 1520

Query: 334  GKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSK 393
            G +G IG  G  G PG  GP G PG     G+ G  G  G  G PG  GPPG +G  G  
Sbjct: 1521 GDIG-IGIAGENGLPGPPGPQGPPGY----GKMGATGPMGQQGIPGIPGPPGPMGQPGKA 1575

Query: 394  GYQGNSGAPGS-------PGVKGAKG 412
            G+   S   G+       P +K  KG
Sbjct: 1576 GHCNPSDCFGAMPMEQQYPPMKTMKG 1601



 Score = 89.4 bits (220), Expect = 1e-17
 Identities = 62/169 (36%), Positives = 80/169 (47%), Gaps = 32/169 (18%)

Query: 226  IDQDTINRIIKVMKHEAYGE--CYKVSCLEIP----GPSGPKGYRGQKGAKGNMGEPGEP 279
            ++ D I R I+    + + E   Y  S ++ P       G  G  G+ GA G  G PG P
Sbjct: 1434 VNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSP 1493

Query: 280  GQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRI 339
            G  G+ G    EG  G PG +G+PG KGEKG+ G        G+AG+N            
Sbjct: 1494 GLPGQIGR---EGRQGLPGVRGLPGTKGEKGDIGI-------GIAGEN------------ 1531

Query: 340  GPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIG 388
               G  G PG +GP GY G+ G+ G  G QG  G PG PG  G PG+ G
Sbjct: 1532 ---GLPGPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAG 1576



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 45/112 (40%), Positives = 58/112 (51%), Gaps = 21/112 (18%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI---------EGPIGF--------- 296
            PGP G  G  G+ GA G+ G PG+ G++GRQG PG+         +G IG          
Sbjct: 1475 PGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLP 1534

Query: 297  --PGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG 346
              PGP+G PG+ G+ G  G  G++G PG+ G  G  GQ GK G   P  C G
Sbjct: 1535 GPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFG 1585



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 32/79 (40%), Positives = 38/79 (48%), Gaps = 7/79 (8%)

Query: 518 PGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPAD------PGPPGEPGPRGP 571
           P   GA        P GP+GG+G+ GL G PG KGEKG   +      P  P +    GP
Sbjct: 318 PCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCA-EGP 376

Query: 572 RGVPGPEGEPGPPGDPGLT 590
           +G  G  G  GP G PG T
Sbjct: 377 KGEKGESGALGPSGLPGST 395


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  301 bits (770), Expect = 2e-81
 Identities = 182/415 (43%), Positives = 210/415 (50%), Gaps = 78/415 (18%)

Query: 252  LEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGR---------QGDPGIEGPIGFPGPKGV 302
            L++PGP G +G  G  GA G +G PG PG  G+         +G+ G+ GP G PGP G+
Sbjct: 853  LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI 912

Query: 303  PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPG-----CKGDPGNRGPDGYP 357
            PG  G  G  G DG +G PGL G  G  G KG+ G  GPPG       G  G +G  G P
Sbjct: 913  PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLP 972

Query: 358  GEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG---SPGVKGAKGG- 413
            G  G  G +G QG  GDPG+PG  G PG  G  G KG  G  G PG    PG+KG  G  
Sbjct: 973  GIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032

Query: 414  --PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPG-----------PEGPRGLAGEVG 460
              PGP+G +G PG  G PG  GSPG  G KG+KGDPG           P+G  GL G  G
Sbjct: 1033 GFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPG 1092

Query: 461  N---KGAKGDRGLPG---------------------PRGPQGALGEPGKQGSRGDPGDAG 496
            N   KG+ GD GLPG                     P GP+G  G PG  G  G+PG  G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVG 1152

Query: 497  PRGDSGQPGP------------------KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGG 538
              G  GQPGP                  KG+PG+PGF  PGP G PG  G+ G  G  G 
Sbjct: 1153 GGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGI 1212

Query: 539  RGDFGL---KGEPGRKGEKGEPADPGPPGEPGP--RGPRGVPGPEGEPGPPGDPG 588
             G+ GL   KGEPG  G  G    PGPPG PGP   GP+G PGP+G PG PG PG
Sbjct: 1213 PGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPG 1267



 Score =  300 bits (769), Expect = 3e-81
 Identities = 191/451 (42%), Positives = 214/451 (47%), Gaps = 91/451 (20%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIE--GPIGFPGPKGVPGFKGEKGEF 312
            PGP G +G  G  G  G  G PG PGQKG +GDPGI   G  G PGPKG PG  G  G  
Sbjct: 1035 PGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 313  GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGK 372
            G  G  G PGL G  GT G KG+ G  G PG  G PG +G  G PG  G PGE G  GG 
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154

Query: 373  GDPGRPG---RRGPPGEIGAKGSKGYQG--------NSGAPGSPGVKGAKG--------- 412
            G PG+PG    +G PG+ G  G  G +G        N G PG PG+ G KG         
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 413  GPGPRGPKGEPGRRGDPGT-----------------KGSPGSDGPKGEKGDPGPEGPRGL 455
             PG  GPKGEPG  G PG                  KG+PG  GP G  G PGPEGP GL
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGL 1274

Query: 456  AGEVGNKGAKGDRGLPG------------PRGPQGALGEPGKQGSRGDPG---------- 493
             G  G KG KG+ G PG            P G QG  G PG  G +GDPG          
Sbjct: 1275 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1334

Query: 494  --------DAGPRGDSGQPGPKGDPGRPGFSY-----------PGPRGAPGEKGEPGPRG 534
                     AGP G+ G  GP G PG PG S            PG  G PG KG PGP+G
Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394

Query: 535  PEGGRGDFGLKGEPGRKG------EKGEPADPGPPGEPGPRGPRGVPGPEG---EPGPPG 585
            P+G  G  G  G+PGR G        G   DPG PG+PG RG  G PGP+G    PGPPG
Sbjct: 1395 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454

Query: 586  DPGLTECDVMTYVRETCGCCDCEKRCGALDV 616
               +    ++T   +T     C +  G L V
Sbjct: 1455 TSSVAHGFLITRHSQTTDAPQCPQ--GTLQV 1483



 Score =  296 bits (758), Expect = 5e-80
 Identities = 183/388 (47%), Positives = 199/388 (51%), Gaps = 52/388 (13%)

Query: 254  IPGPSGPKGYRG------QKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV---PG 304
            IPG SGPKGY+G      Q G  G  G PG PG KG  G PG  G IG PG KG     G
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 305  FKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLG-----RIGPPGCKGDPGNRGPDGYPGE 359
            F G +G  G  G  G PG  G  G  GQKG  G      IG PG  G  G  G  GYPG 
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093

Query: 360  AGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGP 419
             G  G  GD G  G PG PG +G PG  G  G+ G  G  G  G PG  G  G PGP G 
Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153

Query: 420  KGEPGRRGDPGTKGSPGSDG---PKGEKGDPGPEG--PRGLAGEVGNKGAKGD------- 467
             G PG+ G PG KG PG DG   P G+KG+PG  G    G  G  G  G KGD       
Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 468  --RGLPGPRGPQGALGEPGKQGSRGDPGDAGP--RGDSGQPGPKGDPGRPGFSYP----- 518
               GLPGP+G  G  G PG QG  G PG  GP   G  G PGP+G PGRPG   P     
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPG 1273

Query: 519  --------GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR---KGEKGEPADPGPPGEPG 567
                    G +G PG+ G PG  G +G +G  GL+G PGR    G KG+P  PG PG PG
Sbjct: 1274 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333

Query: 568  PRGPRGVP---GPEGEP---GPPGDPGL 589
             +GP GVP   GPEGEP   GPPG PGL
Sbjct: 1334 MKGPSGVPGSAGPEGEPGLIGPPGPPGL 1361



 Score =  294 bits (752), Expect = 3e-79
 Identities = 171/363 (47%), Positives = 191/363 (52%), Gaps = 36/363 (9%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPG--QKGRQGDPGIEGPIGFPGPKGVPGFKGEKG- 310
            + G  GPKG  G  G  G MG PG PG   +G  G PGI GPIG PG  G+PG KG+ G 
Sbjct: 791  LDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850

Query: 311  ----------EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEA 360
                      E G+ G  GAPG  G  G+ G  GK G  G PG KG+ G  GP G PG  
Sbjct: 851  PGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 361  GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG--------------SPG 406
            G PG  G  G KGD G  G+ G PG  G KGSKG  G  G PG               PG
Sbjct: 911  GIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG 970

Query: 407  VKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKG 466
            + G  G  GP+G +G PG  G PG  G PG  GP G KG+PG  G  GL G  G KG  G
Sbjct: 971  LPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIG 1030

Query: 467  DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGE 526
            D G PGP+G +G  G  G  G  G PG  G +GD G PG     G PG   PGP+G PG 
Sbjct: 1031 DMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI-GLPGL--PGPKGEPGL 1087

Query: 527  KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGD 586
             G PG  G +G  GD GL G PG  G KG+P  PG PG PGP      PGP+G  GPPG+
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP------PGPKGISGPPGN 1141

Query: 587  PGL 589
            PGL
Sbjct: 1142 PGL 1144



 Score =  291 bits (745), Expect = 2e-78
 Identities = 173/393 (44%), Positives = 201/393 (51%), Gaps = 57/393 (14%)

Query: 254  IPGPSGPKGYRGQKGAKGNMG--EPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGE 311
            +PGP+G KG +G+ G  G  G  +P   G KG +G+PG+ G  G  GPKG  G  G+ G+
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992

Query: 312  FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRG------------PDGYPGE 359
             G  G+ G PG  G  G  G  G+ G IGPPG KG  G+ G            P G PG+
Sbjct: 993  PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052

Query: 360  AGSPGERGDQGGKGDPG--------------RPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
             GSPG  G +G KGDPG               PG  G PG  G KGS G  G  G PG+P
Sbjct: 1053 PGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 406  GVKGAKG------GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEV 459
            G KG  G       PGP GPKG  G  G+PG  G PG  G  G  G PGP G +G  G+ 
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQD 1172

Query: 460  GNKGAKGDRGLPGPRG--PQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGF-- 515
            G  G  G +G PG  G    G  G PG  G +GD G  G  G+ G PGPKG+PG  GF  
Sbjct: 1173 GIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPG 1232

Query: 516  --SYPGPRGAPGE-----KGEPGPRGPEGG------RGDFGLKGEPGRKGEKGEPADPGP 562
                PGP G+PG      KG PGP+GP G        G  GL G  G KGEKG P  PG 
Sbjct: 1233 VQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGL 1292

Query: 563  PGEPGPRGPRGVPGPEGEPGPP------GDPGL 589
            PG PG +G +G PG +G PG P      GDPGL
Sbjct: 1293 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1325



 Score =  291 bits (744), Expect = 2e-78
 Identities = 177/381 (46%), Positives = 192/381 (50%), Gaps = 54/381 (14%)

Query: 255 PGPSGPKG----YRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPG---FKG 307
           PG  G  G    + G KG KG +G PG PG  G  G PG +G  G PGPKG PG   FKG
Sbjct: 541 PGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKG 600

Query: 308 EKGEFGADGRKGAPGL--------------AGKNGTDGQKGKLGRIGPPGCKGDPGNR-G 352
           E+G  G  G  G PG                G+ G  G  G  G+ G PG KGDPG    
Sbjct: 601 ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 353 PDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG 412
             G PG  G+PG  GD G  GDPG PG+ G PG  G+KG  G  G  G PG PG KG  G
Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPG 719

Query: 413 GPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGD--PGPEGPRGLAGEVGNKGAKGDRGL 470
            PGP G  G PGR G  G  G PG  GPKGE G   PGP GP GL G  G  G KGDRG 
Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779

Query: 471 PGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGP---------- 520
           PGP GP      PG+ G  G PG  G  G +GQPGP G PG PG    GP          
Sbjct: 780 PGPPGP------PGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833

Query: 521 -----RGAPGEKGEPGP-----RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE---PG 567
                 G PGEKG+PGP      GP G RG  G+ G PG  G  G P  PG  G    PG
Sbjct: 834 GQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPG 893

Query: 568 PRGPRGVPGPEGEPGPPGDPG 588
            +G  G+ GP G PGP G PG
Sbjct: 894 TKGEMGMMGPPGPPGPLGIPG 914



 Score =  291 bits (744), Expect = 2e-78
 Identities = 176/388 (45%), Positives = 201/388 (51%), Gaps = 56/388 (14%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG--------PKGVPGF 305
            +PGP GPKG+ G  G  G  G PG  G +G  G PG  GP G PG        P G+PGF
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 306  KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGP---PGCKGDPG--------NRGPD 354
            KG  G  G  G  G PG  G+ G DG  G  G +GP   PG  G PG          GP 
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRR--GPPGEIGAKGSKGYQGNSGAPGSPGVKG--- 409
            G PG  G PG  G  G KGDPG PG    GPPGE G+ G  G  G  G PGSPG+ G   
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 410  AKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRG 469
            A G PG +G  G  G  G PG  G PG  G  G KGD G +G  GL G  G KG+KG+ G
Sbjct: 888  ASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPG 947

Query: 470  LPGPRGPQ-----GALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFS-YPGPRGA 523
            LPGP GP      G+ GE G+ G  G PG +GP+G  G PG   DPG+PG S  PG  G 
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG---DPGQPGLSGQPGLPGP 1004

Query: 524  PGEKGEP---------GPRGPEGGRGDF------GLKGEPGRKGEKGEPADPGPPGEPGP 568
            PG KG P         GP G +G  GD       G++G PG  G  G+P  PG PG+ G 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 569  RGPRGV--------PGPEGEPGPPGDPG 588
            +G  G+        PGP+GEPG PG PG
Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPG 1092



 Score =  289 bits (740), Expect = 6e-78
 Identities = 173/379 (45%), Positives = 193/379 (50%), Gaps = 45/379 (11%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQ----------KGRQGDPGIEGPIGFPGPKGVPG 304
           PGP GP G  G KG +G  G  G+ G            G  G PG+ G  G PG  G PG
Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 305 FKGEKGEFGADGRKGAPGLAGKNGTDG-------------------QKGKLGRIGPPGCK 345
            KGEKG+ GA G KG PG+ G  G  G                    KG+LG  G PG  
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 346 GDPGNRGPDGYPGEAGSPGERGD---QGGKGDPGRPGRRGPPGEIGAKGSKGY--QGNSG 400
           G PG  G DG PG  G  GE G    +G +G PG PG  G PG IG  G  G+   G  G
Sbjct: 573 GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 401 APGSPGVKGAKGGPGPRGPKGEPGRR----GDPGTKGSPGSDGPKGEKGDPGPEGPRGLA 456
             G  GV G  G PG  GPKG+PG+     G PG  G+PG DG  G  GDPG  G  GL 
Sbjct: 633 EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLP 692

Query: 457 GEVGNKGAKG--DRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG 514
           G  G+KG  G    GLPGP GP+G  G PG  G+ G PG  G  G  G PG  G  G PG
Sbjct: 693 GIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPG 752

Query: 515 FSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP---ADPGPPGEPGPRGP 571
           F+ PGP G PG  G  G  GP+G RG  G  G PGR G  G P    D GP G+PGP GP
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 572 RGVP--GPEGEPGPPGDPG 588
            G+P  G +G PGPPG PG
Sbjct: 813 PGLPGIGVQGPPGPPGIPG 831



 Score =  276 bits (705), Expect = 7e-74
 Identities = 166/378 (43%), Positives = 190/378 (50%), Gaps = 57/378 (15%)

Query: 268 GAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKN 327
           G KG  GE G PG +G  G PG  GP G PGP+G  G  G  G  G  G +G PGL G  
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFP 101

Query: 328 GTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEI 387
           GT G  G  G  G PG +G PG  G  G  G  GSPG  G QG  G PG PG +G PG I
Sbjct: 102 GTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSI 161

Query: 388 GAKGSKGYQGNSGAPGSPGVKGAKGG---PGPRGPKGEPGRRGDPGTKGSPGS------- 437
                 G +GN G PG PG++G  G    PGP GP G PG  G PG  G PG        
Sbjct: 162 IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLN 221

Query: 438 -DGPKGEKGDPGPEGPRGLAGEV-------------GNKGAKGDRGLPGP---RGP---- 476
             GPKGEKG+ G +GP G  G++             G++G  GDRG PGP   RGP    
Sbjct: 222 FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPP 281

Query: 477 ---QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPR 533
              +G  GE G+ G RG PG  G  G  G PG  GDPG PG   PG  G  G+KG+ GP 
Sbjct: 282 GGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG--EPGRDGEKGQKGDTGPP 339

Query: 534 GPE-------------GGRGDFGLKGEPGRKGEKGEPADPGPPGEP--------GPRGPR 572
           GP              G +G+ GL G PG KGE+G P   GPPG P        GP GP 
Sbjct: 340 GPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPP 399

Query: 573 GVPGPEGEPGPPGDPGLT 590
           G PG  G+ G  G PG++
Sbjct: 400 GFPGERGQKGDEGPPGIS 417



 Score =  276 bits (705), Expect = 7e-74
 Identities = 182/457 (39%), Positives = 208/457 (45%), Gaps = 120/457 (26%)

Query: 256 GPSGPKGYRGQK-------GAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV------ 302
           GP GP G    +       G KGN+G PG PG+KG +G PGI+GP G PGP G       
Sbjct: 337 GPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPP 396

Query: 303 --PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG----------DPGN 350
             PGF GE+G+ G +G  G   + G  G DGQ G  G  GPPG  G          +PG 
Sbjct: 397 GPPGFPGERGQKGDEGPPGI-SIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 351 RGPDGYPGEAGSPGERGDQGGKGD----------------PGRPGRRGPPGEIGAKGSKG 394
            GP G PG+ G  GE+G +G KGD                PG PG  GPPG +G  G KG
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 395 YQGNSGAPGS---PGVKGAKGGPGPRGPKGEPG-------RRGDPGTKGSPGSDGPKGEK 444
            +G +GA G    PG+ GA G PG  G KGEPG        +GD G  GSPG+ G  G  
Sbjct: 516 EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 445 GDPGPEGPRGLAGEVGNKGA---KGDRGLPG--------------------PRGPQGALG 481
           G PG +G  GL G  G  G    KG+RG PG                    P GP G  G
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKG 635

Query: 482 EPGKQGSRGDPGDAGPRGDSGQ-------------------------------------P 504
             G  G+ G PG  GP+GD GQ                                     P
Sbjct: 636 IQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIP 695

Query: 505 GPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKG---EKGEPA--- 558
           G KG+PG PG   PGP G  G  G PGP G  G  G  GL+G PG  G    KGEP    
Sbjct: 696 GSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFAL 755

Query: 559 --DPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
              PGPPG PG +G  G  G  G PGPPG PG T  D
Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792



 Score =  274 bits (700), Expect = 3e-73
 Identities = 178/447 (39%), Positives = 202/447 (45%), Gaps = 116/447 (25%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPG---------------------QKGRQGDPGIEG 292
           IPGP GPKG RG  G  G  G PG PG                     ++G  G PG  G
Sbjct: 82  IPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG 141

Query: 293 PIGFPGPKGVPGFKGEKGEF------GADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKG 346
             G PGP G+PG KGE G        G  G  G PG  G  G  G  G  G IGPPG  G
Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPG 201

Query: 347 DPGNRGPDGYPGEAGSPGE--RGDQGGKGDPGRPGRRGPPGEIGA----------KGSKG 394
             G  GP G PG  G+ G   +G +G KG+ G  G  GPPG+I            KG +G
Sbjct: 202 LMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQG 261

Query: 395 YQGNSGAPGSPGVKGAKGGPG----PRGPKGEPGRRG------------------DPGTK 432
             G+ G PG PG++G  G PG     +G +GEPG+RG                  DPG  
Sbjct: 262 LPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYP 321

Query: 433 GSPGSDGPKGEKGDPGPEGPRGLA----------GEVGN------KGAKGDRGLPGPRGP 476
           G PG DG KG+KGD GP GP GL           GE GN       G KG+RG PG +GP
Sbjct: 322 GEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP 381

Query: 477 QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKG-------- 528
            G  G PG        G  GP G  G+ G KGD G PG S PGP G  G+ G        
Sbjct: 382 PGLPGPPGAAVM----GPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 529 --------------EPGPRGPEGGRGDFGLKGEPGRKGEKGE-------------PADPG 561
                         EPGP GP G  GD GL+GE G KG+KG+             P  PG
Sbjct: 438 GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG 497

Query: 562 PPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            PG PGP G  G PG +GE G  G  G
Sbjct: 498 LPGLPGPPGSLGFPGQKGEKGQAGATG 524



 Score =  265 bits (678), Expect = 1e-70
 Identities = 178/455 (39%), Positives = 208/455 (45%), Gaps = 109/455 (23%)

Query: 244 GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI---EGPIGFPGPK 300
           GE   +    +PGP G  GY G  G +G  G  G PG  G  G PG+    GP G PGPK
Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 301 GVPG--FKGEKGEFGADGRKGAPGLAG-------------KNGTDGQKGKLGRIGPPGCK 345
           G  G  F+G KGE G  G +G PG  G             + G  G  G  G  GPPG +
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 346 GDP-------GNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGN 398
           G P       G +G  G PG+ G PG+ G+ G  G PG PG  G PGE G  G KG +G+
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 399 SGAPGSPGVK----------GAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGP-------- 440
           +G PG PG+           G KG  G  G  GE G RG PG +G PG  GP        
Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 441 ------KGEKGDPGPEGPRGLA--GEVGNKGAKGDRGLPGPRGPQG-------ALGEPGK 485
                  GE+G  G EGP G++  G  G  G  G  GLPGP GP G        + EPG 
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 486 QGSRGDPGDAGPRGDSGQPGPKGD-------------PGRPGF-SYPGPRGA------PG 525
            G  G PGD G +G+ G  G KGD             PG+PG    PGP G+       G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKG 515

Query: 526 EKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPAD----------------------PGPP 563
           EKG+ G  GP+G  G  G  G PG  G KGEP D                      PG P
Sbjct: 516 EKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLP 575

Query: 564 GEPGPRGPRGVPGPEGEP---------GPPGDPGL 589
           G PG  G  G+PGP+GEP         GPPG+PGL
Sbjct: 576 GTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610



 Score =  202 bits (515), Expect = 8e-52
 Identities = 125/307 (40%), Positives = 148/307 (48%), Gaps = 52/307 (16%)

Query: 320 APGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPG 379
           +PG   K    G KG+ G  G PG +G PG     G+PG  G PG RG +G  G PG   
Sbjct: 33  SPG--SKCDCSGIKGEKGERGFPGLEGHPGL---PGFPGPEGPPGPRGQKGDDGIPG--- 84

Query: 380 RRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDG 439
              PPG  G +G  G  G  G PG PG+ G  G PGP+G    PG  G  G +G PGS G
Sbjct: 85  ---PPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGI---PGCNGTKGERGFPGSPG 138

Query: 440 PKGEKGDPGPEGPRGLAGEVGN------KGAKGDRGLPGPRGPQGALGEPGKQGSRGDPG 493
             G +G PGP G  G+ GE G+       G KG+ G PGP G QG  G  G  G  G PG
Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198

Query: 494 DAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEG-------------GRG 540
             G  G  G PG  G  G  G ++ GP+G  GE+G  GP GP G              +G
Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258

Query: 541 DFGLK-------------------GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEP 581
           D GL                    GE G KGE+GEP   G PG+ G  G  G+PG  G+P
Sbjct: 259 DQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDP 318

Query: 582 GPPGDPG 588
           G PG+PG
Sbjct: 319 GYPGEPG 325



 Score =  175 bits (444), Expect = 1e-43
 Identities = 112/275 (40%), Positives = 133/275 (48%), Gaps = 47/275 (17%)

Query: 361 GSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP---------GVKGAK 411
           G P E     G     +    G  GE G +G  G +G+ G PG P         G KG  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDD 80

Query: 412 GGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLP 471
           G PGP GPKG  G  G PG  G+PG  G  G  G PGP+G  G  G  G +G  G  G P
Sbjct: 81  GIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFP 140

Query: 472 GPRGPQGALGEPGKQGS------------RGDPGDAGP------RGDSGQPGPKGDPGRP 513
           G +GP G  G PG +G             +G+PG  GP       G +G PGP G PG P
Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPP 200

Query: 514 G-FSYPGPRGAPGEKGEPGP--RGPEGGRGDFGLKGEPG----------------RKGEK 554
           G    PGP G PG KG  G   +GP+G +G+ GL+G PG                +KG++
Sbjct: 201 GLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQ 260

Query: 555 GEPADPGPPGEPGPRGPRGVPGPE-GEPGPPGDPG 588
           G P D GPPG PG RGP G PG E GE G  G+PG
Sbjct: 261 GLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPG 295



 Score =  174 bits (442), Expect = 2e-43
 Identities = 109/266 (40%), Positives = 129/266 (48%), Gaps = 41/266 (15%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQ--KGRQGDPGIEGPIG---FPGPKGVPGF--- 305
            +PGP G  G+ G  G +G  G PG PG   +G +G+PG +GP G    PGP+G PG    
Sbjct: 1218 LPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277

Query: 306  ---KGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS 362
               KGEKG  G  G  G PGL G  G  G +G  GR G  G KGDPG  G  G+PG  G 
Sbjct: 1278 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337

Query: 363  PGERGDQGGKGDPGRPGRRGPPGEIGAKGS----KGYQGNSGAPGSPGVKGAKGG----- 413
             G  G  G +G+PG  G  GPPG  G  G     KG  G  G PG PG+KG  G      
Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1397

Query: 414  -PGPRGPKGEPGR------------------RGDPGTKGSPGSDGPKGEKGDPGPEGPRG 454
             PGP GP G+PGR                   G PGT+G  G  GP G +G PGP G   
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSS 1457

Query: 455  LAGEVGNKGAKGDRGLPGPRGPQGAL 480
            +A   G    +  +    P+ PQG L
Sbjct: 1458 VAH--GFLITRHSQTTDAPQCPQGTL 1481



 Score = 80.1 bits (196), Expect = 8e-15
 Identities = 47/108 (43%), Positives = 57/108 (52%), Gaps = 18/108 (16%)

Query: 487 GSRGD-PGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLK 545
           GS+ D  G  G +G+ G PG +G PG PGF  PGP G PG         P G +GD G+ 
Sbjct: 35  GSKCDCSGIKGEKGERGFPGLEGHPGLPGF--PGPEGPPG---------PRGQKGDDGIP 83

Query: 546 GEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLTECD 593
           G PG KG +G      PPG PG  G  G+PG  G  G PG  G+  C+
Sbjct: 84  GPPGPKGIRG------PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  300 bits (769), Expect = 3e-81
 Identities = 163/360 (45%), Positives = 194/360 (53%), Gaps = 28/360 (7%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            +PG SG  G++G KG++G  G PG  G+ G  G  G +G IGFPGP G  GF G+ G  G
Sbjct: 860  VPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPG 919

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
             +G +G  G  G  G  G +G+LG  G  G  G PG  G +G PG  G PG  G  G KG
Sbjct: 920  DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKG 979

Query: 374  DPGRPGRRGP---------------PGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRG 418
            +PG PGR GP               PG +G KG +G  G  G PG  G  G  G PG  G
Sbjct: 980  EPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMG 1039

Query: 419  PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQG 478
              GEPG +G PG++G PG  G KG +G  GP+GP G  G  G KG  G +G PG  G QG
Sbjct: 1040 TPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQG 1099

Query: 479  ALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP----------GPRGAPGEKG 528
              GE G  GSRG PG  GP   SG PG KG PG PG   P          GP+G PG  G
Sbjct: 1100 VAGERGHLGSRGFPGIPGP---SGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVG 1156

Query: 529  EPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            EPG  G  G +GD G  G PG +G  G+  +PG  G+ GP GP G+ G  G+PGP G+ G
Sbjct: 1157 EPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHG 1216



 Score =  297 bits (761), Expect = 2e-80
 Identities = 167/379 (44%), Positives = 204/379 (53%), Gaps = 40/379 (10%)

Query: 244  GECYKVSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV- 302
            G+  K+     PG  G +G  G  G  G +G PG PG  G  GD G+ GPIG+PGPKG+ 
Sbjct: 781  GKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMK 840

Query: 303  --------PGFKGEKGEFGADGRKGAPGLAGKNGTD---------GQKGKLGRIGPPGCK 345
                    PG KG+KGE G  G  G PG  G  G+          G+ G LG++G  G  
Sbjct: 841  GLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI 900

Query: 346  GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAP--- 402
            G PG  GP+G+PG+ G PG+ G +G KG PG  G  GP G++G +G +G  G  GAP   
Sbjct: 901  GFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLE 960

Query: 403  GSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            G PG KG  G PG  G KGEPG  G PG  G  G  G  G  G+P      G+ GE G++
Sbjct: 961  GQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEP------GIVGEKGDR 1014

Query: 463  GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP---- 518
            G  G  G+PGP+G  G  G PG  G+ G+PG  GP G  G PG +G  GR G   P    
Sbjct: 1015 GMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPA 1074

Query: 519  GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP---------PGEPGPR 569
            G +G+ G KG PGP+G  G  G  G+ GE G  G +G P  PGP         PGEPGP+
Sbjct: 1075 GEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQ 1134

Query: 570  GPRGVPGPEGEPGPPGDPG 588
            GP+G  GP GE GP G PG
Sbjct: 1135 GPQGPIGPPGEMGPKGPPG 1153



 Score =  297 bits (761), Expect = 2e-80
 Identities = 165/362 (45%), Positives = 194/362 (53%), Gaps = 26/362 (7%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIG------FPGPKGVPGFKGEK 309
            GP G  G  GQ G KG  G PG  G KG  GDPG  GP+G      F G  G PG  GEK
Sbjct: 952  GPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEK 1011

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGP---------------D 354
            G+ G  G  G PG  G  G  G  G +G  G PG +G PG+RGP               D
Sbjct: 1012 GDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPD 1071

Query: 355  GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
            G  GE GS G +G  G +G PGRPG++G  GE G  GS+G+ G  G  G PG KG  G P
Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEP 1131

Query: 415  GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPR 474
            GP+GP+G  G  G+ G KG PG+ G  G  G+ G +G  G  G  G +G  G RG PG  
Sbjct: 1132 GPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLE 1191

Query: 475  GPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRG 534
            G  G +G  G +G RGDPG  G  G+ GQ G  G+ G PG   PG  G  G +G+ G +G
Sbjct: 1192 GDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG--PPGVTGVRGPEGKSGKQG 1249

Query: 535  PEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEP---GPPGDPGLTE 591
             +G  G  G KG  G+ GE G P DPGPPG PGP+G RG  GP G P   G  G+PGL  
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAG 1309

Query: 592  CD 593
             D
Sbjct: 1310 YD 1311



 Score =  295 bits (754), Expect = 2e-79
 Identities = 163/349 (46%), Positives = 194/349 (55%), Gaps = 20/349 (5%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G KG++G  G  G+ GE G+PG +G  G  G  G  G PGP G PG KG +G  G 
Sbjct: 702  PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGL 761

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G PG  G+ G  G  GK G++G PG  G  G RGP   PG  G+PGE G  G  G 
Sbjct: 762  PGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGP---PGLDGNPGELGLPGPPGV 818

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
            PG  G  G  G IG  G KG +G  G+ G PG+KG KG  G  G  G+PG +GD G++G 
Sbjct: 819  PGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGL 878

Query: 435  P------GSDGPKGEKGD------PGPEGPRGLAGEV---GNKGAKGDRGLPGPRGPQGA 479
            P      G  GP G+ GD      PGP GP G  G++   G+ G +G +G PG RG  G 
Sbjct: 879  PGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGP 938

Query: 480  LGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGR 539
             G+ G +G  G  G  G  G  GQPG KG PGRPG    G +G PG+ G PGP G +G  
Sbjct: 939  RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLD--GVKGEPGDPGRPGPVGEQGFM 996

Query: 540  GDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            G  GL GEPG  GEKG+    GPPG PGP+G  G PG  G  G PG+PG
Sbjct: 997  GFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045



 Score =  293 bits (749), Expect = 6e-79
 Identities = 170/390 (43%), Positives = 201/390 (51%), Gaps = 56/390 (14%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG---PKGVPGFKGEKGE 311
            PGP G  G RG +G  G  GE G  G KG +G  G  G +G PG   P G PG KG +G 
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 312  FG---ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY-------PGEAG 361
             G   A GR GA G  G  G DG KG +G +GPPG KG+ G +G DG        PG+ G
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349

Query: 362  SPGERGDQGGKGDPGRPGRRG------------------------PPGEIGAKGSKGYQG 397
              G+RGD+G  GDPG PG+ G                        P G  GA+G KG QG
Sbjct: 1350 PVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQG 1409

Query: 398  NSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
             +GAPG  GV+G +G PGPRG  G  G  G  G  G PG DG  G++G+ G +G  G  G
Sbjct: 1410 KAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMG 1469

Query: 458  EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG--- 514
              G +G  G  GLPG +GP G  GE G  G  G PG  G  G +G PG +G+PG  G   
Sbjct: 1470 PAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPG 1529

Query: 515  ----FSYPG------PRGAPGE---KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPA--- 558
                  +PG      P+G PG+   KG  GPRGP G  G  G+ G  G  G  G P    
Sbjct: 1530 DSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKG 1589

Query: 559  DPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
            D G  G+ G +GPRG PGP G PGPPG PG
Sbjct: 1590 DKGSRGDWGLQGPRGPPGPRGRPGPPGPPG 1619



 Score =  291 bits (744), Expect = 2e-78
 Identities = 173/384 (45%), Positives = 200/384 (52%), Gaps = 57/384 (14%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE---KG 310
            IPGPSGP       G KG  GEPG  G +G  G PG  GP G PG  G PG  GE   KG
Sbjct: 1115 IPGPSGP------PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKG 1168

Query: 311  EFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQG 370
            + G  G  G  GL G+ G  G +G  G +GP G KGD G+ GPDG  GE G  G  G+ G
Sbjct: 1169 DLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDG 1228

Query: 371  GKGDPGRPGRRGPPGE---------IGAKGSKGYQ---------GNSGAPGSPGVKGAKG 412
              G PG  G RGP G+          GAKG+KGYQ         G+ G PG+PG KG++G
Sbjct: 1229 PPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRG 1288

Query: 413  GPGPRGPKGEPGRRGDPGTKGSP---------GSDGPKGEKGD----------PGPEGPR 453
              GP G  G  G +G+PG  G           G  GPKGEKG+          PGP G R
Sbjct: 1289 SLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDR 1348

Query: 454  GLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD---AGPRGDSGQPGPKGDP 510
            G  G+ G++G  GD G PG  G QG  G+PG+QG  G PG     GP+G  G  GPKG  
Sbjct: 1349 GPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQ 1408

Query: 511  GRPGFSYPGPRGAPGEKGEPGPRGP------EGGRGDFGLKGEPGRKGEKGEPADPGPPG 564
            G+ G   PG RG  G +G PGPRG       EG  G  GL G  G+ G++GE  D G PG
Sbjct: 1409 GKAG--APGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPG 1466

Query: 565  EPGPRGPRGVPGPEGEPGPPGDPG 588
              GP G RG PG  G PG  G PG
Sbjct: 1467 PMGPAGKRGNPGVAGLPGAQGPPG 1490



 Score =  290 bits (743), Expect = 3e-78
 Identities = 166/349 (47%), Positives = 189/349 (54%), Gaps = 28/349 (8%)

Query: 265 GQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLA 324
           G  G KG+ G PG PG  G  G PG  GP G PGP G PG  G  G   A G+KG PGL+
Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPG---AKGQKGDPGLS 681

Query: 325 GKNGTDGQKGKLG------RIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRP 378
                DG KG +G        GPPG KG  G  GP G+PGE G PG  G  G KG PGR 
Sbjct: 682 PGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQ 741

Query: 379 GRRGPPGEIGAKGSKGY---QGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP 435
           G  GP G+ G KGS+GY    G  G PGS G +G  G PG RG  G PG  G  G +G P
Sbjct: 742 GLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPP 801

Query: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495
           G DG  GE G PGP G  GL G++G  G  G  G  G +G  G++GEPG +G +G+ G  
Sbjct: 802 GLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVP 861

Query: 496 GPRGDSGQPGPKGDPGRPGF----SYPGPRGAPGEKGE---PGPRGPEGGRGDF------ 542
           G  GD G  G KG  G PGF      PGP G  G+KG    PGP GPEG  GD       
Sbjct: 862 GVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDN 921

Query: 543 ---GLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
              G+KG+PG +G  G     GP G+ GP GP G PG EG+PG  G PG
Sbjct: 922 GPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPG 970



 Score =  289 bits (740), Expect = 6e-78
 Identities = 173/395 (43%), Positives = 211/395 (53%), Gaps = 65/395 (16%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV------PGFKGEK 309
            GP GP G  G KG  G +GEPG PG+ G +GD G   P+G PG +G+      PG +G+ 
Sbjct: 1138 GPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLG---PLGTPGEQGLIGQRGEPGLEGDS 1194

Query: 310  GEFGADGRKGA---PGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGER 366
            G  G DG KG    PG  G++G  GQ+G +G  GPPG  G  G RGP+G  G+ G  G  
Sbjct: 1195 GPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRT 1254

Query: 367  GDQGGKGDPGR------PGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKG-------- 412
            G +G KG  G+      PG  GPPG  G KGS+G  G +GAPG  G +G  G        
Sbjct: 1255 GAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHK 1314

Query: 413  ---GP-GPRGPKGEPGRRGDPGTK----GSPGSDGPKGEKGD---------PGPEGPRGL 455
               GP GP GPKGE G +G+ G      G PG  GP G++GD         PG EG +GL
Sbjct: 1315 GIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGL 1374

Query: 456  AGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGR 512
             G+ G +G  G    RG PGP+G +GA G  GKQG  G PG  G +G  G PGP+G  GR
Sbjct: 1375 RGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGR 1434

Query: 513  PGFS-YPGPRGAP------------GEKGEPGPRGPEGGRGDFGL------KGEPGRKGE 553
             G     GP G P            G+ G+PGP GP G RG+ G+      +G PG KGE
Sbjct: 1435 QGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGE 1494

Query: 554  KGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
             G P   GPPG+ G  G  G+PG +GEPG  G PG
Sbjct: 1495 SGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPG 1529



 Score =  287 bits (735), Expect = 2e-77
 Identities = 167/366 (45%), Positives = 195/366 (53%), Gaps = 35/366 (9%)

Query: 255  PGPSGPKGYRGQKGA------KGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGE 308
            PG  G KG RG  G       KG+MG PG PG  G  G+PG +GP G  GP G+ G KG 
Sbjct: 1005 PGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
            +G  G DG  G  G  G  G  G +G+ GR G  G  G+ G+ G  G+PG    PG  G 
Sbjct: 1065 RGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG---IPGPSGP 1121

Query: 369  QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEP----- 423
             G KG PG PG +GP G IG  G  G +G  GA G PG+ G  G  G  GP G P     
Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181

Query: 424  -GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGP------RGP 476
             G+RG+PG +G  G  GP G KGD G  GP G  GE G +G  G+ G PGP      RGP
Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241

Query: 477  QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-------GPRGAPGE--- 526
            +G  G+ G++G  G  G  G +G  G+ G  GDPG PG   P       GP GAPG    
Sbjct: 1242 EGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGA 1301

Query: 527  KGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPAD----PGPPGEPGPRGPRGVPGPEGEPG 582
            +GEPG  G +G +G  G  G PG KGEKGE  +     GPPG PG RGP G  G  GEPG
Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG 1361

Query: 583  PPGDPG 588
             PG PG
Sbjct: 1362 DPGYPG 1367



 Score =  287 bits (735), Expect = 2e-77
 Identities = 171/377 (45%), Positives = 198/377 (52%), Gaps = 44/377 (11%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGD---------PGIEGPIGFPGPKGVPGFK 306
            GP+G +G RG KG  G  G PG PGQ+G  G+         PGI GP G PG KG+PG  
Sbjct: 1072 GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEP 1131

Query: 307  GE---------------KGEFGADGRKGAPGLAGKNG------TDGQKGKLGRIGPPGCK 345
            G                KG  GA G  G PG AG  G      T G++G +G+ G PG +
Sbjct: 1132 GPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLE 1191

Query: 346  GDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSP 405
            GD G  GPDG  G+ G PG  G+ G KG  G  G  GPPG  G  G +G +G SG  G  
Sbjct: 1192 GDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEK 1251

Query: 406  GVKGAKGGPGPRGPKGEPGRRGDPGTKGSP------GSDGPKGEKGDPGPEGPRGLAGEV 459
            G  GAKG  G +G  GE G  GDPG  G+P      GS GP G  G  G +G  GLAG  
Sbjct: 1252 GRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYD 1311

Query: 460  GNKGAKGDRGLPGPRGPQGALGEPGK-QGSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSY 517
            G+KG  G  G PGP+G +G  GE GK +G  G PGD GP GD G  G  GDPG PG    
Sbjct: 1312 GHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGV 1371

Query: 518  PGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP------PGEPGPRGP 571
             G RG PG++G+PG  GP G  G  G KG  G KG++G+   PG        G PGPRG 
Sbjct: 1372 QGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGV 1431

Query: 572  RGVPGPEGEPGPPGDPG 588
             G  G EG  GP G PG
Sbjct: 1432 VGRQGLEGIAGPDGLPG 1448



 Score =  283 bits (725), Expect = 4e-76
 Identities = 156/366 (42%), Positives = 190/366 (51%), Gaps = 32/366 (8%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PG  GP G RG KG +G  G  G  G++G +G  G  GP G PG  G  G  GE+G  G+
Sbjct: 1050 PGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGS 1109

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
             G  G PG +G  GT G  G+ G  GP G  G PG  GP G PG  G PG  G+ G KGD
Sbjct: 1110 RGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGD 1169

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G  G  G  G IG +G  G +G+SG  G  G+KG +G PGP G  GE G+ G  G  G 
Sbjct: 1170 LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGP 1229

Query: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494
            PG  G  G +G  G  G +G  G  G KGAKG +G  G  G  G  G PG  G +G  G 
Sbjct: 1230 PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS 1289

Query: 495  AGPRGDSGQPGPKGDPGRPGF----------SYPGPRGAPGEKGE----------PGPRG 534
             GP G  G+ G +G+PG  G+            PGP+G  GE+GE          PG RG
Sbjct: 1290 LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG 1349

Query: 535  PEGGRGDFGLKGEP------------GRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
            P G RGD G  G+P            G+ G++G+P  PGP G PGP+G +G  GP+G+ G
Sbjct: 1350 PVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQG 1409

Query: 583  PPGDPG 588
              G PG
Sbjct: 1410 KAGAPG 1415



 Score =  245 bits (625), Expect = 1e-64
 Identities = 135/293 (46%), Positives = 160/293 (54%), Gaps = 22/293 (7%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQG------DPGIEGPIGFPGPKGVPGFKGEK 309
            GP GP G RG  G +G+ GEPG+PG  G++G       PG +G  G PGP+G PG KG K
Sbjct: 1340 GPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSK 1399

Query: 310  GEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQ 369
            G  G  G++G  G  G+ G  G +G  G  G  G +G  G  GPDG PG  G  G++G+Q
Sbjct: 1400 GAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQ 1459

Query: 370  GGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDP 429
            G  GDPG      P G  G +G+ G  G  GA G PG KG  G PG  GP G+ G  G  
Sbjct: 1460 GDDGDPG------PMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRT 1513

Query: 430  GTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGD---RGLPGPRGPQGALGEPGKQ 486
            G  G+ G  G KG+ GD G  G  G+AG  G KG  GD   +G+ GPRGP      PG  
Sbjct: 1514 GLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP------PGLM 1567

Query: 487  GSRGDPGDAGPRGDSGQPGPKGDPGRPG-FSYPGPRGAPGEKGEPGPRGPEGG 538
            G  G  G  G  G SG PGPKGD G  G +   GPRG PG +G PGP GP GG
Sbjct: 1568 GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGG 1620



 Score =  229 bits (583), Expect = 1e-59
 Identities = 139/299 (46%), Positives = 155/299 (51%), Gaps = 22/299 (7%)

Query: 312 FGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGG 371
           F   G    P L G  G  G  G  G  G PG  G PG RGP G PG  G+PG  G  G 
Sbjct: 612 FHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGA 671

Query: 372 KGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPR---GPKGEPGRRGD 428
           KG  G PG        GAKG  G  G SG PG PG KG KG PGP    G +G+PG  G 
Sbjct: 672 KGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGS 731

Query: 429 PGTKGSPGSDGPKGEKGDPGPEGPR---GLAGEVGNKGAKGDRGL---PGPRGPQGALGE 482
           PG KG PG  G  G  GDPGP+G R   GL G  G  G+ G+RGL   PG RG  G  G 
Sbjct: 732 PGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGF 791

Query: 483 PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPG-------FSYPGPRGAP---GEKGEPGP 532
           PG  G RG PG  G  G+ G PGP G PG  G         YPGP+G     G  GEPG 
Sbjct: 792 PGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGL 851

Query: 533 RGPEGGRGDFGLKGEPGRKGEKGE---PADPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           +G +G +G  G+ G+PG +G+KG    P  PG  G+PGP G  G  G  G PGPPG  G
Sbjct: 852 KGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEG 910



 Score =  203 bits (516), Expect = 6e-52
 Identities = 117/256 (45%), Positives = 136/256 (53%), Gaps = 27/256 (10%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
            PGP G KG  G KG +G  G PG  G +G Q         G PGP+GV G +G +G  G 
Sbjct: 1393 PGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQ---------GLPGPRGVVGRQGLEGIAGP 1443

Query: 315  DGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGD 374
            DG  G  G AG+ G  G  G  G +GP G +G+         PG AG PG +G  G KG+
Sbjct: 1444 DGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGN---------PGVAGLPGAQGPPGFKGE 1494

Query: 375  PGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGS 434
             G PG+ GPPG+ G +G  G  GN G PGS      KG PG  G  G PG  G  G KG 
Sbjct: 1495 SGLPGQLGPPGKRGTEGRTGLPGNQGEPGS------KGQPGDSGEMGFPGMAGLFGPKGP 1548

Query: 435  PGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGD 494
            PG  G KG +G  GP G  G  G VG  G  G  GLPGP+G +G+ G+ G QG RG P  
Sbjct: 1549 PGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPP-- 1606

Query: 495  AGPRGDSGQPGPKGDP 510
             GPRG  G PGP G P
Sbjct: 1607 -GPRGRPGPPGPPGGP 1621



 Score =  193 bits (491), Expect = 5e-49
 Identities = 116/258 (44%), Positives = 132/258 (51%), Gaps = 23/258 (8%)

Query: 339 IGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKG---- 394
           +GPPG KGD G  GP G PG  G PG RG +G  G  G PG  GPPG  G KG  G    
Sbjct: 624 MGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPG 683

Query: 395 --YQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGP 452
             + G  G  G PG+ G  G PG +G KG PG  G PG +G PG +G  G KG PG +G 
Sbjct: 684 KAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGL 743

Query: 453 RGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGR 512
            G  G+ G KG++G  GLPG        G PG  G RG PG  G RG  G PG  G  G 
Sbjct: 744 PGPVGDPGPKGSRGYIGLPG------LFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGE 797

Query: 513 PGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPR 572
            G   PG  G PGE G PGP G  G  GD G+ G  G          PGP G  G  G  
Sbjct: 798 RG--PPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGY---------PGPKGMKGLMGSV 846

Query: 573 GVPGPEGEPGPPGDPGLT 590
           G PG +G+ G  G PG++
Sbjct: 847 GEPGLKGDKGEQGVPGVS 864



 Score =  156 bits (394), Expect = 8e-38
 Identities = 87/186 (46%), Positives = 103/186 (55%), Gaps = 9/186 (4%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFG 313
            I GP G  G  GQ G +G  G+ G+PG  G  G  G  G  G PG +G PGFKGE    G
Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGES---G 1496

Query: 314  ADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGDQGGKG 373
              G+ G P   GK GT+G+ G  G  G PG KG PG+ G  G+PG AG  G +G  G  G
Sbjct: 1497 LPGQLGPP---GKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG 1553

Query: 374  DPGRPGRRGPPGEIGAK---GSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPG 430
              G  G RGPPG +G +   G  G  G SG PG  G KG++G  G +GP+G PG RG PG
Sbjct: 1554 FKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPG 1613

Query: 431  TKGSPG 436
              G PG
Sbjct: 1614 PPGPPG 1619



 Score = 73.6 bits (179), Expect = 7e-13
 Identities = 66/223 (29%), Positives = 80/223 (35%), Gaps = 22/223 (9%)

Query: 386 EIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSP--GSDGPKGE 443
           +I +  SK     +     P        P P    G       P T   P  G+  P+  
Sbjct: 463 KITSHASKPASARTSTHKPPPFTALSSSPAPT--PGSTRSTRPPATMVPPTSGTSTPRTA 520

Query: 444 KGDPGP-EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSG 502
              P P   P G    +G++ +K       PR P      PGK        D   R    
Sbjct: 521 PAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPL--RPGKAARDVPLSDLTTRPSPR 578

Query: 503 QPGPKGD--------PGRPGFSYPGPRGA-------PGEKGEPGPRGPEGGRGDFGLKGE 547
           QP P           P +   S P P  +        G    P   GP G +GD GL G 
Sbjct: 579 QPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGP 638

Query: 548 PGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLT 590
           PG  G  G P   GP G PGP G  G+PGP G  G  GDPGL+
Sbjct: 639 PGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLS 681



 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 23/49 (46%), Positives = 28/49 (57%)

Query: 249  VSCLEIPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFP 297
            V  L I GPSG  G +G KG++G+ G  G  G  G +G PG  GP G P
Sbjct: 1573 VGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  300 bits (768), Expect = 4e-81
 Identities = 161/347 (46%), Positives = 191/347 (55%), Gaps = 29/347 (8%)

Query: 257 PSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADG 316
           P GP G  G  G KG+ G PG+PG++G +G  G  GP G PGP G+ G +G +GE GADG
Sbjct: 565 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 624

Query: 317 R---------KGAPGLAGKNGTDGQKGK---LGRIGPPGCKGDPGNRGPDGYPGEAGSPG 364
                      G PG  G  G  G  G     G  GPPG +G PG  GP G  G +G PG
Sbjct: 625 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 684

Query: 365 ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPG 424
             G++G +G  G+P   GPPGE G  G  G  G  GA G PG KG  G  G  GP+GE G
Sbjct: 685 IPGEEGKEGRDGKP---GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 741

Query: 425 RRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPG 484
             G PG +G PG DG  G  G  GP+GPRG  G+ G+ G+ G+   PGP G  G  G  G
Sbjct: 742 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE---PGPSGTPGQKGSKG 798

Query: 485 KQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGL 544
           + GS G PG  GPRG  G+PG KG PG+         G PG+ GEPG +G  G  G  G 
Sbjct: 799 ENGSPGLPGFLGPRGPPGEPGEKGVPGK--------EGVPGKPGEPGFKGERGDPGIKGD 850

Query: 545 KGEPGRKGEKGEPADPGPPGEPGPRGPRGVP---GPEGEPGPPGDPG 588
           KG PG KG+ G+P  PG  G  G  GP+G+P   GP G PGPPG PG
Sbjct: 851 KGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPG 897



 Score =  296 bits (757), Expect = 7e-80
 Identities = 175/407 (42%), Positives = 204/407 (50%), Gaps = 75/407 (18%)

Query: 256 GPSGPKGYRG-------------QKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGV 302
           GP+GP G  G             ++G KG  G+PG PG+ G QG PG  GP    GP G 
Sbjct: 325 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGP---QGPTGP 381

Query: 303 PGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGS 362
           PG KG++G  GA G  G PG  G  G  G  G  G +G PG +G PG  G  G  G AG 
Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGE 441

Query: 363 PGERGDQGGKGDPGRPGRRGPP-----GEIGAKGSKGY------QGNSGAPGSPGVKGAK 411
            G  G  G +GDPG PG  GPP     GE G +GS G       +G+ GAPG PG  G++
Sbjct: 442 EGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501

Query: 412 GGP-----GPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPG------------------ 448
           G P     GP GP G PG +G PG++G PG  GP+G  G  G                  
Sbjct: 502 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561

Query: 449 ---PEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPR------- 498
              P GP GL G  G KG KG  G PG  G +G  GE G  G  G PG AGP+       
Sbjct: 562 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 621

Query: 499 --GDSGQPGPKGDPGRPGF----SYPGPRGA---------PGEKGEPGPRGPEGGRGDFG 543
             G+ GQ G +G PG PGF      PGP GA         PG +G PG  GP G +G  G
Sbjct: 622 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 681

Query: 544 LKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPPGDPGLT 590
           L G PG +G++G    PGPPGEPG  G  G+PGPEG  GPPG  G T
Sbjct: 682 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 728



 Score =  292 bits (747), Expect = 1e-78
 Identities = 169/379 (44%), Positives = 198/379 (52%), Gaps = 57/379 (15%)

Query: 255 PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGA 314
           PG  G  G  G  G KG+ G PG PG  G +GDPGI G  G PGP G PG KG  G  G 
Sbjct: 471 PGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGL 529

Query: 315 DGRKGAPGLAGKNGTDG--QKGKLGRI----------GPPGCKGDPGNRGPDGYPGEAGS 362
            G  G  G AG++G       G +  +          GPPG  G PG +G  G PG+   
Sbjct: 530 PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGK--- 586

Query: 363 PGERGDQGGKGDPGRPGRRGPPG---------EIGAKGSKGYQGNSGAPGSPGVKGAKGG 413
           PG  G +G KG+ G PG  GPPG         E GA G  G +G+ G PG PG  G  G 
Sbjct: 587 PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN 646

Query: 414 PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGP 473
           PGP G  G  G  G PG +GSPG +GP      PGP+GP GL G  G +G +G  G PGP
Sbjct: 647 PGPPGADGIAGAAGPPGIQGSPGKEGP------PGPQGPSGLPGIPGEEGKEGRDGKPGP 700

Query: 474 RGPQGALGE---PGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGAPGEKGEP 530
            G  G  GE   PG +G+RG PG  G  GDSG PGP+G+ G  G   PG  G PG+ G+ 
Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL--PGQEGLPGKDGDT 758

Query: 531 GPRGPEGGR---------------GDFGLKGEPGRKGEKGEPADPGPPGEPGPRGP---- 571
           GP GP+G +               G+ G  G PG+KG KGE   PG PG  GPRGP    
Sbjct: 759 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818

Query: 572 --RGVPGPEGEPGPPGDPG 588
             +GVPG EG PG PG+PG
Sbjct: 819 GEKGVPGKEGVPGKPGEPG 837



 Score =  288 bits (738), Expect = 1e-77
 Identities = 182/432 (42%), Positives = 208/432 (48%), Gaps = 96/432 (22%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGR------------QGDPGIEGPIGFPGPKGVP 303
            G  G KG +G  G  G MG PG PG  G             QG PG EGP G  GP G+P
Sbjct: 624  GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 683

Query: 304  GFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGD------PGNRGPDG-- 355
            G  GE+G+ G DG+ G PG  GK G  G  G  G  GPPG KG       PG RG  G  
Sbjct: 684  GIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAM 743

Query: 356  -YPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGP 414
              PG+ G PG+ GD G  G  G  G RGPPG+ G+ GS G  G SG PG  G KG  G P
Sbjct: 744  GLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSP 803

Query: 415  G------PRGPKGEPGRRGDPGTKGSPGSDGP---KGEKGDPG------PEGPRGLAGEV 459
            G      PRGP GEPG +G PG +G PG  G    KGE+GDPG      P G +G  G+ 
Sbjct: 804  GLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDP 863

Query: 460  GNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDS------------------ 501
            G  G KG  GL GP+G  G  G  G  G  G PG  G RG+S                  
Sbjct: 864  GIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQL 923

Query: 502  --------------------GQPGPKGDPGRPGF-SYPGPRGAPGEKGE---PGPRGPEG 537
                                G+PGP G PG+ G     GP G PG  G+    GP GP G
Sbjct: 924  ETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 983

Query: 538  GRGDFGLKGEPGR-----KGEKGEPADPGPPGEPG--PRGPRGVPGPEGE---------P 581
             +G+ G KG+PG      +GE G P  PG PGEPG    G  G+PGP+GE         P
Sbjct: 984  PKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLP 1043

Query: 582  GPPGDPGLTECD 593
            GPPG PG  +CD
Sbjct: 1044 GPPGPPG--QCD 1053



 Score =  287 bits (734), Expect = 3e-77
 Identities = 181/441 (41%), Positives = 210/441 (47%), Gaps = 106/441 (24%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGI------------------------ 290
            PG  GP G  G +G++G  G  GE GQKG QG PG+                        
Sbjct: 602  PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP 661

Query: 291  ---------EGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGP 341
                     EGP G  GP G+PG  GE+G+ G DG+ G PG  GK G  G  G  G  GP
Sbjct: 662  PGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 721

Query: 342  PGCKGD------PGNRGPD---GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGS 392
            PG KG       PG RG     G PG+ G PG+ GD G  G  G  G RGPPG+ G+ GS
Sbjct: 722  PGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS 781

Query: 393  KGYQGNSGAPGSPGVKGAKGGP------GPRGPKGEPGRRGDPGTKGSPGSDGP---KGE 443
             G  G SG PG  G KG  G P      GPRGP GEPG +G PG +G PG  G    KGE
Sbjct: 782  PGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 841

Query: 444  KGDP------GPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGP 497
            +GDP      GP G +G  G+ G  G KG  GL GP+G  G  G  G  G  G PG  G 
Sbjct: 842  RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 901

Query: 498  RGDS--------------------------------------GQPGPKGDPGR---PGFS 516
            RG+S                                      G+PGP G PG+   PG +
Sbjct: 902  RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 961

Query: 517  YP-GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGR-----KGEKGEPADPGPPGEPG--P 568
             P G  G PG+ G  GP GP G +G+ G KG+PG      +GE G P  PG PGEPG   
Sbjct: 962  GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1021

Query: 569  RGPRGVPGPEGEPGPPGDPGL 589
             G  G+PGP+GE GP G PGL
Sbjct: 1022 DGLPGIPGPQGETGPAGHPGL 1042



 Score =  285 bits (729), Expect = 1e-76
 Identities = 170/388 (43%), Positives = 201/388 (51%), Gaps = 60/388 (15%)

Query: 258 SGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPKGVPGFKGEKGEFGADGR 317
           +G  G RG+ G  G  G  GE G++G  G PG +G  G PG  G PG +GEKG+ G  G 
Sbjct: 249 NGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 308

Query: 318 KGAPGLAGKNGTDGQKGKLGRIGPPGCKGD----------PGNRGPDGYPGEAGSPGERG 367
            G PGL G     G+KG+ G  GPPG  G           PG +GP G  G+ G PGE G
Sbjct: 309 LGLPGLKGDR---GEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG 365

Query: 368 DQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRG 427
            QG  G+ G  G  GPPG  G +G+ G  G +G PG+PG  GA G  GP G  G PG RG
Sbjct: 366 LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRG 425

Query: 428 DPGTKGSPGSDGPKGEKGDPGPEGPRG-----------LAGEVGNKGAKGDRGLPGP--- 473
            PG  G  G  G  GE+G PGP GPRG             G+ G  G +G  GLPGP   
Sbjct: 426 TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 485

Query: 474 RGPQGALGEPGKQGSRGDP--GDAGPRGDSGQPGPKGDPGRPGF-SYPGPRG-------- 522
           +G +GA G PG  GSRGDP  G AGP G SG PG KG PG  G   +PGP+G        
Sbjct: 486 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS 545

Query: 523 ---APGE-------------KGEPGPRGPEGGRGDFGLKGEPGR------KGEKGEPADP 560
              +PG+              G PG  G  G +GD G+ G+PGR      KGE G P  P
Sbjct: 546 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 605

Query: 561 GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           GPPG  GP+G +G  G +GE G  GD G
Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQG 633



 Score =  278 bits (711), Expect = 1e-74
 Identities = 164/388 (42%), Positives = 193/388 (49%), Gaps = 56/388 (14%)

Query: 256 GPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGP---IGFPGPKGVPGFKGEKGEF 312
           GP+GP G +GQ+GA G  G  G PG  G  G PG  GP   +G PG +G PG  GE+GE 
Sbjct: 377 GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 436

Query: 313 GADGRKGAPGLAGKNGTDGQKGK-----LGRIGPPGCKGDPGNRGPDGYPGEAGSPGERG 367
           GA G +G+PG  G  G  G  G       G+ G PG +G PG  GP G  G+ G+PG  G
Sbjct: 437 GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPG 496

Query: 368 DQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGG-------------- 413
             G +GDPG  G  GPPG  G  G KG  G+ G PG PG +G  G               
Sbjct: 497 SPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINL 555

Query: 414 ----------PGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP-------------- 449
                     PGP G  G PG +GD G  G PG +G +G+KG+ GP              
Sbjct: 556 LAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQG 615

Query: 450 -EGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQG---SRGDPGDAGPRGDSGQPG 505
            +G RG  GEVG KG +G  G+PG  GP G  G PG  G   + G PG  G  G  G PG
Sbjct: 616 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 675

Query: 506 PKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGE 565
           P+G  G PG   PG  G  G  G+PGP G  G  G+ GL G  G +G  G     G  G 
Sbjct: 676 PQGPSGLPGI--PGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA 733

Query: 566 PGPR---GPRGVPGPEGEPGPPGDPGLT 590
           PGPR   G  G+PG EG PG  GD G T
Sbjct: 734 PGPRGESGAMGLPGQEGLPGKDGDTGPT 761



 Score =  276 bits (707), Expect = 4e-74
 Identities = 165/411 (40%), Positives = 196/411 (47%), Gaps = 77/411 (18%)

Query: 254 IPGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPGPK---GVPGFKGEKG 310
           +PG  G +G  G++G  G  GE GE G  G  G PG+ G  G  G K   G+PG KG++G
Sbjct: 260 LPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRG 319

Query: 311 EFGADGRKGAPGL-------------AGKNGTDGQKGKLGRIGPPGCKGDPGNRGPD--- 354
           E G  G  G PGL              G+ G  G+KG  G  G PG +G PG  GP    
Sbjct: 320 EKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPT 379

Query: 355 ------GYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVK 408
                 G  G  G+PG  G+ G  G  G PG  GPPG +GA G +G  G  G  G  G  
Sbjct: 380 GPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 439

Query: 409 GAKGGPGPRGPKGEP-----------GRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAG 457
           G +G PGP GP+G+P           G+ G+PG +GSPG  GP G KGD G  G  G  G
Sbjct: 440 GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPG 499

Query: 458 EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSG--------------- 502
             G+ G  G  G PGP GP G  G PG +G  G PG  GP G  G               
Sbjct: 500 SRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAK 558

Query: 503 ------QPGPKGDPGRPGF-------SYPGPRGAPGEKGEPGP---------RGPEGGRG 540
                  PGP G PG PGF         PG  G  G+KGE GP          GP+G +G
Sbjct: 559 DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQG 618

Query: 541 DFGLKGEPGRKGEKGEPADP---GPPGEPGPRGPRGVPGPEGEPGPPGDPG 588
           + G  GE G+KG++G P  P   GPPG PGP G  G+ G  G PG  G PG
Sbjct: 619 ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 669



 Score =  254 bits (648), Expect = 3e-67
 Identities = 154/370 (41%), Positives = 180/370 (48%), Gaps = 54/370 (14%)

Query: 255  PGPSGPKGYRGQKGAKGNMGEPGEPGQKGRQGDPGIEGPIGFPG------PKGVPGFKGE 308
            PG  GP+G RG  G KG+ G+ G PG +G  G  G+ G  G PG      P G  G +G 
Sbjct: 710  PGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP 769

Query: 309  KGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGYPGEAGSPGERGD 368
            +G  G +G  G+PG  G +GT GQKG  G  G PG  G  G RGP G PGE G PG+ G 
Sbjct: 770  RGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGV 829

Query: 369  QGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGAKGGPGPRGPKGEPGRRGD 428
             G  G+PG  G RG PG    KG KG  G  G PG PG+ G KG  G  GP+G PG  G 
Sbjct: 830  PGKPGEPGFKGERGDPG---IKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 886

Query: 429  PGTKGSPGSDGPKGEKGD-PGPEGPRGLAGEVGNKG----------------AKGDRGLP 471
             G  G PG  G  G +G+ P  E  R L  E   K                  K  +G P
Sbjct: 887  VGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP 946

Query: 472  GPRGP---------QGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRG 522
            GP GP          G +GEPG+ G  G  G +GP G  G+ G KGDPG PG    G  G
Sbjct: 947  GPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMG 1006

Query: 523  APGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPG 582
             PG  G+P               GEPG   + G P  PGP GE GP G  G+PGP   PG
Sbjct: 1007 PPGIPGQP---------------GEPG-YAKDGLPGIPGPQGETGPAGHPGLPGP---PG 1047

Query: 583  PPGDPGLTEC 592
            PPG    ++C
Sbjct: 1048 PPGQCDPSQC 1057



 Score =  244 bits (622), Expect = 3e-64
 Identities = 145/340 (42%), Positives = 168/340 (49%), Gaps = 49/340 (14%)

Query: 300 KGVPGFK---GEKGEFGADGRKGAPGLAGKNGTDGQKGKLGRIGPPGCKGDPGNRGPDGY 356
           K  PG K   GE GE G DG  G PGL G+            IG  G  G PG +G  G 
Sbjct: 240 KTAPGLKQLNGEPGERGEDGLPGKPGLRGE------------IGEQGLAGRPGEKGEAGL 287

Query: 357 PGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKGA------ 410
           PG  G PG RG+   KGD G  G  G PG  G +G KG  G +G PG PG          
Sbjct: 288 PGAPGFPGVRGE---KGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPR 344

Query: 411 -KGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGP---EGPRGLAGEVGNKGAKG 466
             G  GP+G KG+PG  G+PG +G PG  GP+G  G PG    EG  G  G  GN GA G
Sbjct: 345 MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG 404

Query: 467 DRGLPGPRGPQGALGEPG------KQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYP-- 518
             G PGP GP G++G PG      K G RG+ G AG  G  G  GP+GDPG PG   P  
Sbjct: 405 HVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG 464

Query: 519 -GPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEP--ADPGPPGEPGPRGPRGVP 575
            G  G PG +G PG  GP G +GD G  G PG  G +G+P     GPPG  GP G +G P
Sbjct: 465 KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSP 524

Query: 576 GPEGEPGPPGDPG----------LTECDVMTYVRETCGCC 605
           G  G PG PG  G          L+  D+    ++ C  C
Sbjct: 525 GSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDC 564



 Score =  162 bits (411), Expect = 9e-40
 Identities = 109/302 (36%), Positives = 129/302 (42%), Gaps = 70/302 (23%)

Query: 358 GEAGSPGERGDQGGKGDPGRPGRRGPPGEIG---------------AKGSKGYQGNSGAP 402
           G    P E  DQG +G  GR      P  +                A G++G        
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231

Query: 403 GSPGVKGAKGGPGPRGPKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNK 462
            +  +  AK  PG +   GEPG RG+ G  G PG  G  GE+G  G  G +G AG  G  
Sbjct: 232 RASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAP 291

Query: 463 GAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQP------------------ 504
           G  G RG  G +G +G LG PG +G RG+ G+AGP G  G P                  
Sbjct: 292 GFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGP 351

Query: 505 -GPKGDPGRPG----------FSYPGPRGAPGEKGE---------------------PGP 532
            G KGDPG PG              GP G PG KG+                     PGP
Sbjct: 352 KGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGP 411

Query: 533 RGPEGGRGDFGLKGEPGRKGEKGEPADPGPPGEPGPRGPRGVPGPEGEPGPP-----GDP 587
            GP G  G  GL+G PG+ GE+GE    G  G PGP GPRG PG  G PGPP     G+P
Sbjct: 412 SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 471

Query: 588 GL 589
           GL
Sbjct: 472 GL 473



 Score =  103 bits (256), Expect = 9e-22
 Identities = 75/232 (32%), Positives = 90/232 (38%), Gaps = 80/232 (34%)

Query: 256  GPSGPKGYRGQKGAKGNMGEPGEPGQKGR------QGDPGIEGPIGFPGPKGVPGFKGEK 309
            G  G KG +G  G KG  G+PG PG KG       QG PG  GP+G PGP G PGF G +
Sbjct: 843  GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLR 902

Query: 310  GEF-----------------------------------GADGRKGAPGLAGKNGTDGQKG 334
            GE                                     + GR G PG  GK+G  G+ G
Sbjct: 903  GESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG 962

Query: 335  KLGRIGPPG------------------CKGDPG--------NRGPDGYPGEAGSPG---- 364
             +G  G PG                   KGDPG          GP G PG+ G PG    
Sbjct: 963  PMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKD 1022

Query: 365  -------ERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPGSPGVKG 409
                    +G+ G  G PG PG  GPPG+        +   +  PG+  VKG
Sbjct: 1023 GLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGN--VKG 1072



 Score = 32.0 bits (71), Expect = 2.4
 Identities = 14/28 (50%), Positives = 16/28 (57%)

Query: 254  IPGPSGPKGYRGQKGAKGNMGEPGEPGQ 281
            +PG  GP+G  G  G  G  G PG PGQ
Sbjct: 1024 LPGIPGPQGETGPAGHPGLPGPPGPPGQ 1051


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.140    0.437 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,288,755
Number of Sequences: 37866
Number of extensions: 3378934
Number of successful extensions: 125295
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 438
Number of HSP's successfully gapped in prelim test: 1314
Number of HSP's that attempted gapping in prelim test: 13772
Number of HSP's gapped (non-prelim): 15610
length of query: 828
length of database: 18,247,518
effective HSP length: 111
effective length of query: 717
effective length of database: 14,044,392
effective search space: 10069829064
effective search space used: 10069829064
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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