Guide to the Human Genome
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Search of human proteins with 11321607

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|11321607 thyroid hormone receptor interactor 13 [Homo
sapiens]
         (432 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|11321607 thyroid hormone receptor interactor 13 [Homo sapiens]     846   0.0  
gi|6005942 valosin-containing protein [Homo sapiens]                   72   1e-12
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]          70   4e-12
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]           69   6e-12
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]               66   7e-11
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                  65   1e-10
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                  65   1e-10
gi|156564401 vesicle-fusing ATPase [Homo sapiens]                      63   5e-10
gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive fa...    62   8e-10
gi|157671927 spermatogenesis associated 5 [Homo sapiens]               62   1e-09
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                      62   1e-09
gi|4505725 peroxin1 [Homo sapiens]                                     61   2e-09
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]                60   5e-09
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]                60   5e-09
gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]      60   5e-09
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]             59   1e-08
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]        58   1e-08
gi|31742536 fidgetin-like 1 [Homo sapiens]                             57   2e-08
gi|112789543 fidgetin-like 1 [Homo sapiens]                            57   2e-08
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]             57   3e-08
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]             57   4e-08
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...    56   7e-08
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...    56   7e-08
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]    56   7e-08
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]            55   1e-07
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]              54   2e-07
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            54   3e-07
gi|40806170 spastin isoform 2 [Homo sapiens]                           53   6e-07
gi|11875211 spastin isoform 1 [Homo sapiens]                           53   6e-07
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]      47   3e-05

>gi|11321607 thyroid hormone receptor interactor 13 [Homo sapiens]
          Length = 432

 Score =  846 bits (2186), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 1   MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE 60
           MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE
Sbjct: 1   MDEAVGDLKQALPCVAESPTVHVEVHQRGSSTAKKEDINLSVRKLLNRHNIVFGDYTWTE 60

Query: 61  FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII 120
           FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII
Sbjct: 61  FDEPFLTRNVQSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENII 120

Query: 121 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP 180
           AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP
Sbjct: 121 AANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGP 180

Query: 181 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI 240
           PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI
Sbjct: 181 PGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLI 240

Query: 241 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN 300
           DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN
Sbjct: 241 DDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSN 300

Query: 301 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG 360
           ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG
Sbjct: 301 ITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIG 360

Query: 361 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK 420
           FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK
Sbjct: 361 FIENNVSKLSLLLNDISRKSEGLSGRVLRKLPFLAHALYVQAPTVTIEGFLQALSLAVDK 420

Query: 421 QFEERKKLAAYI 432
           QFEERKKLAAYI
Sbjct: 421 QFEERKKLAAYI 432


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score = 71.6 bits (174), Expect = 1e-12
 Identities = 71/267 (26%), Positives = 116/267 (43%), Gaps = 35/267 (13%)

Query: 71  QSVSIIDTELKVKDSQPIDLSACTVALHIFQLNEDGPSSENLEEETENIIAANHWVLPAA 130
           + + +ID E +  D++ ++  A T+    + L++  PS+  L E    +           
Sbjct: 425 KKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSA--LRETVVEVPQVT------- 475

Query: 131 EFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCK 190
                W+ +    +VK  L + V   +   DK +   + T ++ VL +GPPG GKT L K
Sbjct: 476 -----WEDIGGLEDVKRELQELVQYPVEHPDKFLKFGM-TPSKGVLFYGPPGCGKTLLAK 529

Query: 191 ALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVL 250
           A+A +              I I    L + WF ES   V ++F K +     + A   + 
Sbjct: 530 AIANEC---------QANFISIKGPELLTMWFGESEANVREIFDKAR-----QAAPCVLF 575

Query: 251 IDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV 310
            DE++S+  AR     G     A RV+N +LT++D +    NV I+  +N  + ID A +
Sbjct: 576 FDELDSIAKARGG-NIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAIL 634

Query: 311 DRADIKQYIGPP-----SAAAIFKIYL 332
               + Q I  P     S  AI K  L
Sbjct: 635 RPGRLDQLIYIPLPDEKSRVAILKANL 661



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 46/160 (28%), Positives = 77/160 (48%), Gaps = 20/160 (12%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R +LL+GPPGTGKT + +A+A +                IN   + SK   ES   + K 
Sbjct: 239 RGILLYGPPGTGKTLIARAVANETG---------AFFFLINGPEIMSKLAGESESNLRKA 289

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN 292
           F++      +K+A   + IDE++++   R       E     R+V+ +LT +D +K+ ++
Sbjct: 290 FEEA-----EKNAPAIIFIDELDAIAPKREKTHGEVER----RIVSQLLTLMDGLKQRAH 340

Query: 293 VVILTTSNITEKIDVAF--VDRADIKQYIGPPSAAAIFKI 330
           V+++  +N    ID A     R D +  IG P A    +I
Sbjct: 341 VIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGRLEI 380


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score = 70.1 bits (170), Expect = 4e-12
 Identities = 54/164 (32%), Positives = 85/164 (51%), Gaps = 21/164 (12%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R +LL GPPGTGK+ L KA+A        +         I+S  L SKW  ES KLV  +
Sbjct: 168 RGILLFGPPGTGKSYLAKAVA--------TEANNSTFFSISSSDLVSKWLGESEKLVKNL 219

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQI-KRHS 291
           FQ  +   ++K +++F  IDE++SL  +R+      E   A R+    L Q+  +   + 
Sbjct: 220 FQLAR---ENKPSIIF--IDEIDSLCGSRSE----NESEAARRIKTEFLVQMQGVGVDND 270

Query: 292 NVVILTTSNITEKIDVAFVDRADIKQYI---GPPSAAAIFKIYL 332
            +++L  +NI   +D A   R + + YI    P + AA+FK++L
Sbjct: 271 GILVLGATNIPWVLDSAIRRRFEKRIYIPLPEPHARAAMFKLHL 314


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score = 69.3 bits (168), Expect = 6e-12
 Identities = 62/214 (28%), Positives = 98/214 (45%), Gaps = 44/214 (20%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R +LL GPPGTGK+ L KA+A        +         ++S  L SKW  ES KLV  +
Sbjct: 161 RGILLFGPPGTGKSYLAKAVA--------TEANNSTFFSVSSSDLMSKWLGESEKLVKNL 212

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQI-KRHS 291
           F+  +     K +++F  IDEV+SL  +RN      E   A R+    L Q+  +   + 
Sbjct: 213 FELAR---QHKPSIIF--IDEVDSLCGSRNE----NESEAARRIKTEFLVQMQGVGNNND 263

Query: 292 NVVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLL 351
             ++L  +NI   +D A   R + + YI  P  AA                    R Q+ 
Sbjct: 264 GTLVLGATNIPWVLDSAIRRRFEKRIYIPLPEEAA--------------------RAQMF 303

Query: 352 TLRELEMIGFIENNVSKLSLLLNDISRKSEGLSG 385
            L     +G   +N++  +  +++++RK+EG SG
Sbjct: 304 RLH----LGSTPHNLTDAN--IHELARKTEGYSG 331


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score = 65.9 bits (159), Expect = 7e-11
 Identities = 46/153 (30%), Positives = 80/153 (52%), Gaps = 16/153 (10%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           +LL+GPPGTGKT L KA+A +                I++ ++ SKW  +S KLV  +F+
Sbjct: 218 LLLYGPPGTGKTLLAKAVATECKT---------TFFNISASTIVSKWRGDSEKLVRVLFE 268

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVV 294
                +    A   + +DE+ES+ + R    +G E   ++R+   +L Q+D + R  ++V
Sbjct: 269 -----LARYHAPSTIFLDELESVMSQRGTA-SGGEHEGSLRMKTELLVQMDGLARSEDLV 322

Query: 295 -ILTTSNITEKIDVAFVDRADIKQYIGPPSAAA 326
            +L  SN+  ++D A + R + +  +  PS  A
Sbjct: 323 FVLAASNLPWELDCAMLRRLEKRILVDLPSREA 355


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 62/237 (26%), Positives = 105/237 (44%), Gaps = 32/237 (13%)

Query: 102 LNEDGPSSENLEE----ETENIIAANHWVLPAAEFHGL-------WDSLVYDVEVKSHLL 150
           L +  P SE   +    E  + I A   V P+A+  G        W  +    +++  L 
Sbjct: 429 LRDQDPLSEEQMQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDIREELT 488

Query: 151 DYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLI 210
             ++  +   D+     L+T    VLL GPPG GKT L KA+A +  +           I
Sbjct: 489 MAILAPVRNPDQFKALGLVT-PAGVLLAGPPGCGKTLLAKAVANESGLNF---------I 538

Query: 211 EINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEP 270
            +    L + +  ES + V ++FQ+ ++      A   +  DEV++L   R+    G   
Sbjct: 539 SVKGPELLNMYVGESERAVRQVFQRAKN-----SAPCVIFFDEVDALCPRRSDRETGA-- 591

Query: 271 SDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRADIKQYIGPPSAA 325
             ++RVVN +LT++D ++    V I+  +N  + ID A +   R D   ++G P  A
Sbjct: 592 --SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 646



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VLLHGPPG GKT L  A+A +L +          ++++ +  + S    ES + + ++
Sbjct: 193 RGVLLHGPPGCGKTLLAHAIAGELDL---------PILKVAAPEIVSGVSGESEQKLREL 243

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR--- 289
           F++        +A   + IDE++++T  R       E     R+V  +LT +D +     
Sbjct: 244 FEQAV-----SNAPCIIFIDEIDAITPKREVASKDMER----RIVAQLLTCMDDLNNVAA 294

Query: 290 HSNVVILTTSNITEKIDVAF--VDRADIKQYIGPPSAAAIFKIYLSCLEEL 338
            + V+++  +N  + +D A     R D +  +G P  A+  +I  +   +L
Sbjct: 295 TARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRKL 345


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score = 65.1 bits (157), Expect = 1e-10
 Identities = 62/237 (26%), Positives = 105/237 (44%), Gaps = 32/237 (13%)

Query: 102 LNEDGPSSENLEE----ETENIIAANHWVLPAAEFHGL-------WDSLVYDVEVKSHLL 150
           L +  P SE   +    E  + I A   V P+A+  G        W  +    +++  L 
Sbjct: 535 LRDQDPLSEEQMQGLCIELNDFIVALSSVQPSAKREGFVTVPNVTWADIGALEDIREELT 594

Query: 151 DYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLI 210
             ++  +   D+     L+T    VLL GPPG GKT L KA+A +  +           I
Sbjct: 595 MAILAPVRNPDQFKALGLVT-PAGVLLAGPPGCGKTLLAKAVANESGLNF---------I 644

Query: 211 EINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEP 270
            +    L + +  ES + V ++FQ+ ++      A   +  DEV++L   R+    G   
Sbjct: 645 SVKGPELLNMYVGESERAVRQVFQRAKN-----SAPCVIFFDEVDALCPRRSDRETGA-- 697

Query: 271 SDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRADIKQYIGPPSAA 325
             ++RVVN +LT++D ++    V I+  +N  + ID A +   R D   ++G P  A
Sbjct: 698 --SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 752



 Score = 49.3 bits (116), Expect = 7e-06
 Identities = 43/171 (25%), Positives = 81/171 (47%), Gaps = 23/171 (13%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VLLHGPPG GKT L  A+A +L +          ++++ +  + S    ES + + ++
Sbjct: 299 RGVLLHGPPGCGKTLLAHAIAGELDL---------PILKVAAPEIVSGVSGESEQKLREL 349

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR--- 289
           F++        +A   + IDE++++T  R       E     R+V  +LT +D +     
Sbjct: 350 FEQAV-----SNAPCIIFIDEIDAITPKREVASKDMER----RIVAQLLTCMDDLNNVAA 400

Query: 290 HSNVVILTTSNITEKIDVAF--VDRADIKQYIGPPSAAAIFKIYLSCLEEL 338
            + V+++  +N  + +D A     R D +  +G P  A+  +I  +   +L
Sbjct: 401 TARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASRERILQTLCRKL 451


>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
          Length = 744

 Score = 63.2 bits (152), Expect = 5e-10
 Identities = 41/153 (26%), Positives = 79/153 (51%), Gaps = 15/153 (9%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMF- 233
           +LL+GPPG GKT L + + + L  R        +   +N   + +K+  ES   + K+F 
Sbjct: 256 ILLYGPPGCGKTLLARQIGKMLNAR--------EPKVVNGPEILNKYVGESEANIRKLFA 307

Query: 234 --QKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHS 291
             ++ Q  +     L  ++ DE++++   R +    T   D   VVN +L++ID +++ +
Sbjct: 308 DAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDT--VVNQLLSKIDGVEQLN 365

Query: 292 NVVILTTSNITEKIDVAFV--DRADIKQYIGPP 322
           N++++  +N  + ID A +   R ++K  IG P
Sbjct: 366 NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLP 398



 Score = 30.8 bits (68), Expect = 2.5
 Identities = 25/85 (29%), Positives = 40/85 (47%), Gaps = 17/85 (20%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           VLL GPP +GKT+L   +A++            ++I           FSE+ K      Q
Sbjct: 539 VLLEGPPHSGKTALAAKIAEESNFPFIKICSPDKMI----------GFSETAKC-----Q 583

Query: 235 KIQDLIDD--KDALVFVLIDEVESL 257
            ++ + DD  K  L  V++D++E L
Sbjct: 584 AMKKIFDDAYKSQLSCVVVDDIERL 608


>gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
           factor [Homo sapiens]
          Length = 563

 Score = 62.4 bits (150), Expect = 8e-10
 Identities = 41/153 (26%), Positives = 79/153 (51%), Gaps = 15/153 (9%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMF- 233
           +LL+GPPG GKT L + + + L  R        +   +N   + +K+  ES   + K+F 
Sbjct: 329 ILLYGPPGCGKTLLARQIGKMLNAR--------EPKVVNGPEILNKYVGESEANIRKLFA 380

Query: 234 --QKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHS 291
             ++ Q  +     L  ++ DE++++   R +    T   D   VVN +L++ID +++ +
Sbjct: 381 DAEEEQRRLGANSGLHIIIFDEIDAICKQRGSMAGSTGVHDT--VVNQLLSKIDGMEQLN 438

Query: 292 NVVILTTSNITEKIDVAFV--DRADIKQYIGPP 322
           N++++  +N  + ID A +   R ++K  IG P
Sbjct: 439 NILVIGMTNRPDLIDEALLRPGRLEVKMEIGLP 471


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 49/161 (30%), Positives = 80/161 (49%), Gaps = 21/161 (13%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           VLL+GPPG  KT + KALA +  +           + I    L +K+  ES + V + F+
Sbjct: 664 VLLYGPPGCSKTMIAKALANESGL---------NFLAIKGPELMNKYVGESERAVRETFR 714

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVV 294
           K + +     A   +  DE+++L   R +       +D  RV+  +LT++D I++  +V 
Sbjct: 715 KARAV-----APSIIFFDELDALAVERGSSLGAGNVAD--RVLAQLLTEMDGIEQLKDVT 767

Query: 295 ILTTSNITEKIDVAFV--DRADIKQYIGPPSAAA---IFKI 330
           IL  +N  ++ID A +   R D   Y+  P AA    IFK+
Sbjct: 768 ILAATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKL 808



 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 70/252 (27%), Positives = 116/252 (46%), Gaps = 41/252 (16%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VLL+GPPGTGKT + +A+A ++   +S          IN   + SK++   G+   K+
Sbjct: 388 RGVLLYGPPGTGKTMIARAVANEVGAYVS---------VINGPEIISKFY---GETEAKL 435

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQI---KR 289
            Q   +      +++F  IDE+++L   R   +   E     RVV ++LT +D I     
Sbjct: 436 RQIFAEATLRHPSIIF--IDELDALCPKREGAQNEVEK----RVVASLLTLMDGIGSEVS 489

Query: 290 HSNVVILTTSNITEKIDVAF--VDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPR 347
              V++L  +N    +D A     R D +  IG P+A    +  L  L++L++       
Sbjct: 490 EGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNA----QDRLDILQKLLR-----RV 540

Query: 348 QQLLTLRELEMIGFIENNV--SKLSLLLNDISRKSEGLSG--RVLRKLPFLAHALYVQAP 403
             LLT  EL  +    +    + L +L N+      GL    R+L+K P L         
Sbjct: 541 PHLLTEAELLQLANSAHGYVGADLKVLCNE-----AGLCALRRILKKQPNLPDVKVAGLV 595

Query: 404 TVTIEGFLQALS 415
            +T++ FLQA++
Sbjct: 596 KITLKDFLQAMN 607


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 74/260 (28%), Positives = 115/260 (44%), Gaps = 59/260 (22%)

Query: 136 WDSLVYDVEVKSHLLDYVMTTLLFSD--KNVNSNLITWNRVVLLHGPPGTGKTSLCKALA 193
           WD +   VE K  L + V+  +   +  K +      W  V+++ GPPGTGKT L KA+A
Sbjct: 208 WDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRR---PWKGVLMV-GPPGTGKTLLAKAVA 263

Query: 194 QKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDE 253
            +                ++S +L SK+  ES KLV  +F+  +       A +F  IDE
Sbjct: 264 TECKT---------TFFNVSSSTLTSKYRGESEKLVRLLFEMARFY---SPATIF--IDE 309

Query: 254 VESLTAARNACRAGTEPSDAIRVVNA-VLTQIDQIKRHSN-------VVILTTSNITEKI 305
           ++S+ + R      +E  +A R V A +L Q+D +   S        V++L  +N    I
Sbjct: 310 IDSICSRRGT----SEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDI 365

Query: 306 DVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENN 365
           D A   R + + YI  PSA           EEL++          ++LRELE+   ++  
Sbjct: 366 DEALRRRLEKRIYIPLPSAKG--------REELLR----------ISLRELELADDVD-- 405

Query: 366 VSKLSLLLNDISRKSEGLSG 385
                  L  I+   EG SG
Sbjct: 406 -------LASIAENMEGYSG 418


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 57/197 (28%), Positives = 88/197 (44%), Gaps = 21/197 (10%)

Query: 136  WDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQK 195
            WD +    EV+  L+D +     + +   N   I     +LL+GPPGTGKT L   +A++
Sbjct: 839  WDKIGGLHEVRQILMDTIQLPAKYPELFANLP-IRQRTGILLYGPPGTGKTLLAGVIARE 897

Query: 196  LTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVE 255
                  SR  +   I +    L SK+   S + V  +F + Q     K  ++F   DE E
Sbjct: 898  ------SRMNF---ISVKGPELLSKYIGASEQAVRDIFIRAQAA---KPCILF--FDEFE 943

Query: 256  SLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRA 313
            S+   R     G       RVVN +LTQ+D ++    V +L  ++  + ID A +   R 
Sbjct: 944  SIAPRRGHDNTGVTD----RVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRL 999

Query: 314  DIKQYIGPPSAAAIFKI 330
            D   Y  PP   +  +I
Sbjct: 1000 DKCVYCPPPDQVSRLEI 1016



 Score = 28.9 bits (63), Expect = 9.5
 Identities = 39/181 (21%), Positives = 75/181 (41%), Gaps = 20/181 (11%)

Query: 172 NRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTK 231
           N  +LL G  G+GK++L KA+ ++   +L +         ++  +L  K      K +  
Sbjct: 592 NGALLLTGGKGSGKSTLAKAICKEAFDKLDAHVE-----RVDCKALRGKRLENIQKTLEV 646

Query: 232 MFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAI---RVVNAVLTQIDQ-I 287
            F +   +         VL+D+++ L A   A        DA+   R+ +A+   I + I
Sbjct: 647 AFSEAVWMQPS-----VVLLDDLD-LIAGLPAVPEHEHSPDAVQSQRLAHALNDMIKEFI 700

Query: 288 KRHSNVVILTTSNITEKIDVAFVDRADIK-----QYIGPPSAAAIFKIYLSCLEELMKCQ 342
              S V ++ TS   + +    V    +      Q+I PP+     +I  + ++  + C 
Sbjct: 701 SMGSLVALIATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCD 760

Query: 343 I 343
           I
Sbjct: 761 I 761


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 71/259 (27%), Positives = 110/259 (42%), Gaps = 57/259 (22%)

Query: 136 WDSLVYDVEVKSHLLDYVMTTLLFSD--KNVNSNLITWNRVVLLHGPPGTGKTSLCKALA 193
           WD +    E K  L + V+  +   D  K +      W  V+++ GPPGTGKT L KA+A
Sbjct: 207 WDDIADLEEAKKLLREAVVLPMWMPDFFKGIRR---PWKGVLMV-GPPGTGKTMLAKAVA 262

Query: 194 QKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDE 253
            +                ++S +L SK+  ES KLV  +F+  +       A   + IDE
Sbjct: 263 TECGT---------TFFNVSSSTLTSKYRGESEKLVRLLFEMARFY-----APTTIFIDE 308

Query: 254 VESLTAARNACRAGTEPSDAIRVVNAVLTQIDQI-------KRHSNVVILTTSNITEKID 306
           ++S+ + R       E   + RV + +L Q+D +            V++L  +N    ID
Sbjct: 309 IDSICSRRG---TSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDID 365

Query: 307 VAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNV 366
            A   R + + YI  P+A            EL+K          + LRE+E+   I+   
Sbjct: 366 EALRRRLEKRIYIPLPTAKG--------RAELLK----------INLREVELDPDIQ--- 404

Query: 367 SKLSLLLNDISRKSEGLSG 385
                 L DI+ K EG SG
Sbjct: 405 ------LEDIAEKIEGYSG 417


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 71/259 (27%), Positives = 110/259 (42%), Gaps = 57/259 (22%)

Query: 136 WDSLVYDVEVKSHLLDYVMTTLLFSD--KNVNSNLITWNRVVLLHGPPGTGKTSLCKALA 193
           WD +    E K  L + V+  +   D  K +      W  V+++ GPPGTGKT L KA+A
Sbjct: 207 WDDIADLEEAKKLLREAVVLPMWMPDFFKGIRR---PWKGVLMV-GPPGTGKTMLAKAVA 262

Query: 194 QKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDE 253
            +                ++S +L SK+  ES KLV  +F+  +       A   + IDE
Sbjct: 263 TECGT---------TFFNVSSSTLTSKYRGESEKLVRLLFEMARFY-----APTTIFIDE 308

Query: 254 VESLTAARNACRAGTEPSDAIRVVNAVLTQIDQI-------KRHSNVVILTTSNITEKID 306
           ++S+ + R       E   + RV + +L Q+D +            V++L  +N    ID
Sbjct: 309 IDSICSRRG---TSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDID 365

Query: 307 VAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKCQIIYPRQQLLTLRELEMIGFIENNV 366
            A   R + + YI  P+A            EL+K          + LRE+E+   I+   
Sbjct: 366 EALRRRLEKRIYIPLPTAKG--------RAELLK----------INLREVELDPDIQ--- 404

Query: 367 SKLSLLLNDISRKSEGLSG 385
                 L DI+ K EG SG
Sbjct: 405 ------LEDIAEKIEGYSG 417


>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
          Length = 361

 Score = 59.7 bits (143), Expect = 5e-09
 Identities = 62/224 (27%), Positives = 96/224 (42%), Gaps = 27/224 (12%)

Query: 115 ETENIIAANHWVLPAAEFHGLWDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRV 174
           E E  IAA H V P    H  W  +    +V + L D V+  +       NS L+   + 
Sbjct: 71  EYEMSIAA-HLVDPL-NMHVTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKG 128

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           VLL+GPPG GKT + KA A++   R          I +   +L  KW+ ES KL   +F 
Sbjct: 129 VLLYGPPGCGKTLIAKATAKEAGCR---------FINLQPSTLTDKWYGESQKLAAAVFS 179

Query: 235 ---KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHS 291
              K+Q  I        + IDE++S    RN   +  E +  ++     L          
Sbjct: 180 LAIKLQPSI--------IFIDEIDSF--LRNRSSSDHEATAMMKAQFMSLWDGLDTDHSC 229

Query: 292 NVVILTTSNITEKIDVAFVDRADIKQYIGPPS---AAAIFKIYL 332
            V+++  +N  + +D A + R   + +I  P+     AI K+ L
Sbjct: 230 QVIVMGATNRPQDLDSAIMRRMPTRFHINQPALKQREAILKLIL 273


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 44/164 (26%), Positives = 78/164 (47%), Gaps = 20/164 (12%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           V+L+GPPGTGKT L KA+A + +            + +    L  K+  +  KLV ++F+
Sbjct: 222 VILYGPPGTGKTLLAKAVANQTS---------ATFLRVVGSELIQKYLGDGPKLVRELFR 272

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVV 294
                + ++ A   V IDE++++   R    +G E  +  R +  +L Q+D      +V 
Sbjct: 273 -----VAEEHAPSIVFIDEIDAIGTKRYDSNSGGE-REIQRTMLELLNQLDGFDSRGDVK 326

Query: 295 ILTTSNITEKIDVAFVDRADIKQYIGPP-----SAAAIFKIYLS 333
           ++  +N  E +D A +    I + I  P     +   IF+I+ S
Sbjct: 327 VIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTS 370


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score = 58.2 bits (139), Expect = 1e-08
 Identities = 56/224 (25%), Positives = 105/224 (46%), Gaps = 38/224 (16%)

Query: 136 WDSLVYDVEVKSHLLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQK 195
           W+ +    +VK  L   +   L F  + V   L T  + VLL+GPPG  KT+L +ALA  
Sbjct: 463 WEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGL-TQPKGVLLYGPPGCAKTTLVRALATS 521

Query: 196 LTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVE 255
                     +   + ++   LFS +  +S K+++++F++ +       A++F  +DE++
Sbjct: 522 C---------HCSFVSVSGADLFSPFVGDSEKVLSQIFRQAR---ASTPAILF--LDEID 567

Query: 256 SLTAARNACRAGTEPSDAIRVVNAVLTQIDQI------KRHS-------------NVVIL 296
           S+  AR+A + G +  +  RV++ +L ++D +      +R S             +V+I+
Sbjct: 568 SILGARSASKTGCDVQE--RVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMII 625

Query: 297 TTSNITEKIDVAFV--DRADIKQYIGPPSAAAIFKIYLSCLEEL 338
             +N  + +D A +   R D   YI PP       I   C + +
Sbjct: 626 AATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTM 669



 Score = 53.1 bits (126), Expect = 5e-07
 Identities = 46/153 (30%), Positives = 78/153 (50%), Gaps = 19/153 (12%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VLL GPPG GKT L +A+A         R    +L+ +++ +L      E+ + V ++
Sbjct: 235 RGVLLAGPPGVGKTQLVRAVA---------REAGAELLAVSAPALQGSRPGETEENVRRV 285

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN 292
           FQ+ ++L     +L+F  +DE+++L   R     G+   ++ RVV  VLT +D       
Sbjct: 286 FQRARELASRGPSLLF--LDEMDALCPQR-----GSRAPES-RVVAQVLTLLDGASGDRE 337

Query: 293 VVILTTSNITEKIDVAF--VDRADIKQYIGPPS 323
           VV++  +N  + +D A     R D +  IG P+
Sbjct: 338 VVVVGATNRPDALDPALRRPGRFDREVVIGTPT 370


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 20/169 (11%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           +LL GPPGTGKT + K +A +      S         I++ SL SKW  E  K+V  +F 
Sbjct: 437 ILLFGPPGTGKTLIGKCIASQSGATFFS---------ISASSLTSKWVGEGEKMVRALFA 487

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHS--N 292
             +     + A++F  IDE++SL +     R   E   + R+    L Q+D     S   
Sbjct: 488 VAR---CQQPAVIF--IDEIDSLLSQ----RGDGEHESSRRIKTEFLVQLDGATTSSEDR 538

Query: 293 VVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKC 341
           ++++  +N  ++ID A   R   + YI  P A+A  +I ++ + +   C
Sbjct: 539 ILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCC 587


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 49/169 (28%), Positives = 81/169 (47%), Gaps = 20/169 (11%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           +LL GPPGTGKT + K +A +      S         I++ SL SKW  E  K+V  +F 
Sbjct: 437 ILLFGPPGTGKTLIGKCIASQSGATFFS---------ISASSLTSKWVGEGEKMVRALFA 487

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHS--N 292
             +     + A++F  IDE++SL +     R   E   + R+    L Q+D     S   
Sbjct: 488 VAR---CQQPAVIF--IDEIDSLLSQ----RGDGEHESSRRIKTEFLVQLDGATTSSEDR 538

Query: 293 VVILTTSNITEKIDVAFVDRADIKQYIGPPSAAAIFKIYLSCLEELMKC 341
           ++++  +N  ++ID A   R   + YI  P A+A  +I ++ + +   C
Sbjct: 539 ILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCC 587


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score = 57.0 bits (136), Expect = 3e-08
 Identities = 44/162 (27%), Positives = 80/162 (49%), Gaps = 20/162 (12%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           VLL+GPPGTGKT L +A+A                I ++   L  K+  E  ++V ++F 
Sbjct: 186 VLLYGPPGTGKTLLARAVAHHTDC---------TFIRVSGSELVQKFIGEGARMVRELF- 235

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVV 294
               ++  + A   + +DE++S+ ++R    +G + S+  R +  +L Q+D  +   N+ 
Sbjct: 236 ----VMAREHAPSIIFMDEIDSIGSSRLEGGSGGD-SEVQRTMLELLNQLDGFEATKNIK 290

Query: 295 ILTTSNITEKIDVAFV--DRADIKQYIGPPSAAA---IFKIY 331
           ++  +N  + +D A +   R D K    PP+  A   I KI+
Sbjct: 291 VIMATNRIDILDSALLRPGRIDRKIEFPPPNEEARLDILKIH 332


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 47/166 (28%), Positives = 78/166 (46%), Gaps = 20/166 (12%)

Query: 176 LLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQK 235
           +L GPPGTGKT L KA A +  +           I ++       +       V  +F  
Sbjct: 345 ILTGPPGTGKTLLAKATAGEANV---------PFITVSGSEFLEMFVGVGPARVRDLF-- 393

Query: 236 IQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVVI 295
               +  K+A   + IDE++++   R     G + S+    +N +L ++D     +NVVI
Sbjct: 394 ---ALARKNAPCILFIDEIDAVGRKRGRGNFGGQ-SEQENTLNQLLVEMDGFNTTTNVVI 449

Query: 296 LTTSNITEKIDVAFV--DRADIKQYIGPP---SAAAIFKIYLSCLE 336
           L  +N  + +D A +   R D + +IGPP     A+IFK++L  L+
Sbjct: 450 LAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLK 495


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 15/138 (10%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VL++GPPG GKT L KA+A   T            I +       K+  E  ++V  +
Sbjct: 196 RGVLMYGPPGCGKTMLAKAVAHHTT---------AAFIRVVGSEFVQKYLGEGPRMVRDV 246

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN 292
           F+     +  ++A   + IDE++++   R   + G +  +  R++  +L Q+D   ++ N
Sbjct: 247 FR-----LAKENAPAIIFIDEIDAIATKRFDAQTGAD-REVQRILLELLNQMDGFDQNVN 300

Query: 293 VVILTTSNITEKIDVAFV 310
           V ++  +N  + +D A +
Sbjct: 301 VKVIMATNRADTLDPALL 318


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 15/138 (10%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VL++GPPG GKT L KA+A   T            I +       K+  E  ++V  +
Sbjct: 169 RGVLMYGPPGCGKTMLAKAVAHHTT---------AAFIRVVGSEFVQKYLGEGPRMVRDV 219

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN 292
           F+     +  ++A   + IDE++++   R   + G +  +  R++  +L Q+D   ++ N
Sbjct: 220 FR-----LAKENAPAIIFIDEIDAIATKRFDAQTGAD-REVQRILLELLNQMDGFDQNVN 273

Query: 293 VVILTTSNITEKIDVAFV 310
           V ++  +N  + +D A +
Sbjct: 274 VKVIMATNRADTLDPALL 291


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 15/138 (10%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R VL++GPPG GKT L KA+A   T            I +       K+  E  ++V  +
Sbjct: 200 RGVLMYGPPGCGKTMLAKAVAHHTT---------AAFIRVVGSEFVQKYLGEGPRMVRDV 250

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSN 292
           F+     +  ++A   + IDE++++   R   + G +  +  R++  +L Q+D   ++ N
Sbjct: 251 FR-----LAKENAPAIIFIDEIDAIATKRFDAQTGAD-REVQRILLELLNQMDGFDQNVN 304

Query: 293 VVILTTSNITEKIDVAFV 310
           V ++  +N  + +D A +
Sbjct: 305 VKVIMATNRADTLDPALL 322


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 47/162 (29%), Positives = 81/162 (50%), Gaps = 22/162 (13%)

Query: 176 LLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQK 235
           LL+GPPGTGKT L +A+A +L             +++ S S+  K+  ES +L+ +MF  
Sbjct: 185 LLYGPPGTGKTLLARAVASQLDC---------NFLKVVSSSIVDKYIGESARLIREMFNY 235

Query: 236 IQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAI-RVVNAVLTQIDQIKRHSNVV 294
            +   D +  ++F  +DE++++   R +   GT     I R +  +L Q+D       V 
Sbjct: 236 AR---DHQPCIIF--MDEIDAIGGRRFS--EGTSADREIQRTLMELLNQMDGFDTLHRVK 288

Query: 295 ILTTSNITEKIDVAFV--DRADIKQYIGPPSAAA---IFKIY 331
           ++  +N  + +D A +   R D K +I  P+  A   I KI+
Sbjct: 289 MIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIH 330


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 21/188 (11%)

Query: 149 LLDYVMTTLLFSDKNVNSNLITWNRVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQ 208
           L + V T LL  ++ VN   I   + VLL GPPGTGKT   +A+A +             
Sbjct: 187 LREVVETPLLHPERFVNLG-IEPPKGVLLFGPPGTGKTLCARAVANRTD---------AC 236

Query: 209 LIEINSHSLFSKWFSESGKLVTKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGT 268
            I +    L  K+  E  ++V ++F+  +     K  L+F   DE++++  AR    AG 
Sbjct: 237 FIRVIGSELVQKYVGEGARMVRELFEMAR---TKKACLIF--FDEIDAIGGARFDDGAGG 291

Query: 269 EPSDAIRVVNAVLTQIDQIKRHSNVVILTTSNITEKIDVAFV--DRADIKQYIGPPSAAA 326
           + ++  R +  ++ Q+D      N+ +L  +N  + +D A +   R D K     P    
Sbjct: 292 D-NEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEG 350

Query: 327 ---IFKIY 331
              IFKI+
Sbjct: 351 RTHIFKIH 358


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 53.9 bits (128), Expect = 3e-07
 Identities = 36/136 (26%), Positives = 68/136 (50%), Gaps = 16/136 (11%)

Query: 175 VLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKMFQ 234
           +LLHGPPGTGKT L KA+A + ++           + +    L + +  +S + V ++F 
Sbjct: 740 LLLHGPPGTGKTLLAKAVATECSL---------TFLSVKGPELINMYVGQSEENVREVFA 790

Query: 235 KIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKRHSNVV 294
           + +       A   +  DE++SL  +R   R+G       RVV+ +L ++D +    +V 
Sbjct: 791 RAR-----AAAPCIIFFDELDSLAPSRG--RSGDSGGVMDRVVSQLLAELDGLHSTQDVF 843

Query: 295 ILTTSNITEKIDVAFV 310
           ++  +N  + +D A +
Sbjct: 844 VIGATNRPDLLDPALL 859



 Score = 31.2 bits (69), Expect = 1.9
 Identities = 15/33 (45%), Positives = 19/33 (57%)

Query: 168 LITWNRVVLLHGPPGTGKTSLCKALAQKLTIRL 200
           L+T    VLL GPPG GKT++  A    L + L
Sbjct: 459 LLTGTSSVLLRGPPGCGKTTVVAAACSHLGLHL 491


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 20/153 (13%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R +LL GPPG GKT L KA+A +                I++ SL SK+  E  KLV  +
Sbjct: 344 RGLLLFGPPGNGKTMLAKAVAAESN---------ATFFNISAASLTSKYVGEGEKLVRAL 394

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR--H 290
           F   ++L   + +++F  IDEV+SL   R   R G E   + R+    L + D ++    
Sbjct: 395 FAVAREL---QPSIIF--IDEVDSLLCER---REG-EHDASRRLKTEFLIEFDGVQSAGD 445

Query: 291 SNVVILTTSNITEKIDVAFVDRADIKQYIGPPS 323
             V+++  +N  +++D A + R   + Y+  P+
Sbjct: 446 DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPN 478


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 46/153 (30%), Positives = 76/153 (49%), Gaps = 20/153 (13%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLTIRLSSRYRYGQLIEINSHSLFSKWFSESGKLVTKM 232
           R +LL GPPG GKT L KA+A +                I++ SL SK+  E  KLV  +
Sbjct: 376 RGLLLFGPPGNGKTMLAKAVAAESN---------ATFFNISAASLTSKYVGEGEKLVRAL 426

Query: 233 FQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR--H 290
           F   ++L   + +++F  IDEV+SL   R   R G E   + R+    L + D ++    
Sbjct: 427 FAVAREL---QPSIIF--IDEVDSLLCER---REG-EHDASRRLKTEFLIEFDGVQSAGD 477

Query: 291 SNVVILTTSNITEKIDVAFVDRADIKQYIGPPS 323
             V+++  +N  +++D A + R   + Y+  P+
Sbjct: 478 DRVLVMGATNRPQELDEAVLRRFIKRVYVSLPN 510


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 36/139 (25%), Positives = 67/139 (48%), Gaps = 19/139 (13%)

Query: 173 RVVLLHGPPGTGKTSLCKALAQKLT---IRLSSRYRYGQLIEINSHSLFSKWFSESGKLV 229
           R  L +GPPGTGKT + +ALA + +    R++   R G           SKW  ES + +
Sbjct: 461 RGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGA-------DCLSKWVGESERQL 513

Query: 230 TKMFQKIQDLIDDKDALVFVLIDEVESLTAARNACRAGTEPSDAIRVVNAVLTQIDQIKR 289
             +F +   +   + +++F   DE++ L   R++ +     S    +V+ +L  +D +  
Sbjct: 514 RLLFDQAYQM---RPSIIF--FDEIDGLAPVRSSRQDQIHSS----IVSTLLALMDGLDS 564

Query: 290 HSNVVILTTSNITEKIDVA 308
              +V++  +N  + ID A
Sbjct: 565 RGEIVVIGATNRLDSIDPA 583


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,914,870
Number of Sequences: 37866
Number of extensions: 591298
Number of successful extensions: 1697
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 1578
Number of HSP's gapped (non-prelim): 112
length of query: 432
length of database: 18,247,518
effective HSP length: 105
effective length of query: 327
effective length of database: 14,271,588
effective search space: 4666809276
effective search space used: 4666809276
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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