Search of human proteins with 112789543

Search of human proteins with 112789543

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|112789543 fidgetin-like 1 [Homo sapiens]
         (674 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31742536 fidgetin-like 1 [Homo sapiens]                           1351   0.0  
gi|112789543 fidgetin-like 1 [Homo sapiens]                          1351   0.0  
gi|64084766 fidgetin [Homo sapiens]                                   382   e-106
gi|40806170 spastin isoform 2 [Homo sapiens]                          336   4e-92
gi|11875211 spastin isoform 1 [Homo sapiens]                          336   4e-92
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               254   1e-67
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               254   1e-67
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     253   3e-67
gi|116292174 fidgetin-like 2 [Homo sapiens]                           244   2e-64
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]         226   5e-59
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]          225   9e-59
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]              223   3e-58
gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]     191   1e-48
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              177   4e-44
gi|6005942 valosin-containing protein [Homo sapiens]                  169   6e-42
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       160   3e-39
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 154   3e-37
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 154   3e-37
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   151   2e-36
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   151   2e-36
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   151   2e-36
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            148   2e-35
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           146   5e-35
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            144   2e-34
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            140   4e-33
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             139   7e-33
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   137   4e-32
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     135   9e-32
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           132   1e-30
gi|4505725 peroxin1 [Homo sapiens]                                    128   2e-29

>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 1351 bits (3497), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK 60
           MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK
Sbjct: 1   MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK 60

Query: 61  KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ 120
           KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ
Sbjct: 61  KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ 120

Query: 121 AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN 180
           AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN
Sbjct: 121 AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN 180

Query: 181 RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV 240
           RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV
Sbjct: 181 RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV 240

Query: 241 FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE 300
           FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE
Sbjct: 241 FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE 300

Query: 301 QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP 360
           QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP
Sbjct: 301 QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP 360

Query: 361 YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP 420
           YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP
Sbjct: 361 YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP 420

Query: 421 MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK 480
           MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK
Sbjct: 421 MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK 480

Query: 481 MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL 540
           MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL
Sbjct: 481 MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL 540

Query: 541 VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS 600
           VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS
Sbjct: 541 VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS 600

Query: 601 DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL 660
           DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL
Sbjct: 601 DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL 660

Query: 661 ELYENWNKTFGCGK 674
           ELYENWNKTFGCGK
Sbjct: 661 ELYENWNKTFGCGK 674


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 1351 bits (3497), Expect = 0.0
 Identities = 674/674 (100%), Positives = 674/674 (100%)

Query: 1   MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK 60
           MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK
Sbjct: 1   MQTSSSRSVHLSEWQKNYFAITSGICTGPKADAYRAQILRIQYAWANSEISQVCATKLFK 60

Query: 61  KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ 120
           KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ
Sbjct: 61  KYAEKYSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQ 120

Query: 121 AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN 180
           AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN
Sbjct: 121 AGKKFKDSLLEPALASVVIHKEATVFDLPKFSVCGSSQESDSLPNSAHDRDRTQDFPESN 180

Query: 181 RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV 240
           RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV
Sbjct: 181 RLKLLQNAQPPMVTNTARTCPTFSAPVGESATAKFHVTPLFGNVKKENHSSAKENIGLNV 240

Query: 241 FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE 300
           FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE
Sbjct: 241 FLSNQSCFPAACENPQRKSFYGSGTIDALSNPILNKACSKTEDNGPKEDSSLPTFKTAKE 300

Query: 301 QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP 360
           QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP
Sbjct: 301 QLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGILGKFVPPIPKQDGGEQNGGMQCKP 360

Query: 361 YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP 420
           YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP
Sbjct: 361 YGAGPTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWP 420

Query: 421 MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK 480
           MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK
Sbjct: 421 MLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEK 480

Query: 481 MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL 540
           MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL
Sbjct: 481 MVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRIL 540

Query: 541 VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS 600
           VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS
Sbjct: 541 VVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQS 600

Query: 601 DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL 660
           DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL
Sbjct: 601 DAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL 660

Query: 661 ELYENWNKTFGCGK 674
           ELYENWNKTFGCGK
Sbjct: 661 ELYENWNKTFGCGK 674


>gi|64084766 fidgetin [Homo sapiens]
          Length = 759

 Score =  382 bits (982), Expect = e-106
 Identities = 192/392 (48%), Positives = 271/392 (69%), Gaps = 7/392 (1%)

Query: 288 EDSSLPTFKTAKEQLWVDQQKKYH-QPQRA-SGSSYGGVKKSLGASRSRGILGKFVPPIP 345
           E SSL  FK  K+ +  +QQ+K+  Q  RA +  SY   K SLG SRS    GK+  P+ 
Sbjct: 370 ETSSL-AFKPTKQLMSSEQQRKFSSQSSRALTPPSYSTAKNSLG-SRSSESFGKYTSPVM 427

Query: 346 KQDGGEQNGGMQCKPYGAG---PTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWED 402
            + G E    +     G G    T   H VDE+LKN +  +I+L+ NEI+  GPPV+W D
Sbjct: 428 SEHGDEHRQLLSHPMQGPGLRAATSSNHSVDEQLKNTDTHLIDLVTNEIITQGPPVDWND 487

Query: 403 IAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATF 462
           IAG++  KA IKE V+WP+LR D F+GL   P+ ILLFGP GTGKTL+G+CIASQ GATF
Sbjct: 488 IAGLDLVKAVIKEEVLWPVLRSDAFSGLTALPRSILLFGPRGTGKTLLGRCIASQLGATF 547

Query: 463 FSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKT 522
           F I+ S L +KW+GE EK++ A F VARC+QP+VIF+ +ID LLS + + EH    R++T
Sbjct: 548 FKIAGSGLVAKWLGEAEKIIHASFLVARCRQPSVIFVSDIDMLLSSQVNEEHSPVSRMRT 607

Query: 523 EFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMS 582
           EFL+QLD   TS+ED+I+V+ AT++P+EIDE+ RR  +KRL IPLP+++AR QI++ L+S
Sbjct: 608 EFLMQLDTVLTSAEDQIVVICATSKPEEIDESLRRYFMKRLLIPLPDSTARHQIIVQLLS 667

Query: 583 KEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYI 642
           +   CL+++E   +VQ+++ FSG D+  LC+EA +GP+ ++   D++ I P Q+RP+ Y 
Sbjct: 668 QHNYCLNDKEFALLVQRTEGFSGLDVAHLCQEAVVGPLHAMPATDLSAIMPSQLRPVTYQ 727

Query: 643 DFENAFRTVRPSVSPKDLELYENWNKTFGCGK 674
           DFENAF  ++PS+S K+L++Y  WNK FGC +
Sbjct: 728 DFENAFCKIQPSISQKELDMYVEWNKMFGCSQ 759



 Score = 83.2 bits (204), Expect = 7e-16
 Identities = 54/152 (35%), Positives = 80/152 (52%), Gaps = 7/152 (4%)

Query: 12  SEWQKNYFAITSGICT-GPKADAYRAQILRI-QYAWANSEISQVCATKLFKKYAEKYSAI 69
           ++W + +F ITS   +   K +AYR  + R  QYAWAN +IS + A+ L KKYAEKYS I
Sbjct: 19  AQWPEQHFDITSTTRSPAHKVEAYRGHLQRTYQYAWANDDISALTASNLLKKYAEKYSGI 78

Query: 70  IDSDNVESGLNNYAENILTLAGSQQTDSDKWQSGLSINNVFKMSSVQKMMQAGKKFKDSL 129
           ++       L+NY++    L   ++ +S+ WQ  L+   V+ M+ V  ++ A K    S 
Sbjct: 79  LEGPVDRPVLSNYSDTPSGLVNGRKNESEPWQPSLNSEAVYPMNCVPDVITASKAGVSSA 138

Query: 130 LEPALASVVIHKE---ATVFDLPKF--SVCGS 156
           L PA  S  I      A+    P +  S CGS
Sbjct: 139 LPPADVSASIGSSPGVASNLTEPSYSSSTCGS 170


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score =  336 bits (862), Expect = 4e-92
 Identities = 174/397 (43%), Positives = 254/397 (63%), Gaps = 17/397 (4%)

Query: 277 ACSKTEDNGPKEDSSLPTFKTAKEQLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGI 336
           A  K +D      +SLP  KT  +         +  P  +  S   GVK+  G       
Sbjct: 199 AVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQGSG------- 251

Query: 337 LGKFVPPIPKQDGGEQNGGMQCKPYGAGPTEPAHPVDE--RLKNLEPKMIELIMNEIMDH 394
                 P P    G        KP  + PT       +    +N++  +  LIMNEI+D+
Sbjct: 252 ------PAPTTHKGTPKTNRTNKP--STPTTATRKKKDLKNFRNVDSNLANLIMNEIVDN 303

Query: 395 GPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCI 454
           G  V ++DIAG + AK  ++EIV+ P LRP++FTGLR P +G+LLFGPPG GKT++ K +
Sbjct: 304 GTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAV 363

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A++S ATFF+ISA+SLTSK+VGEGEK+VRALFAVAR  QP++IFIDE+DSLL +R +GEH
Sbjct: 364 AAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEH 423

Query: 515 ESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARK 574
           ++SRR+KTEFL++ DG  ++ +DR+LV+GATNRPQE+DEA  RR +KR+Y+ LP    R 
Sbjct: 424 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRL 483

Query: 575 QIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPD 634
            ++ NL+ K+   L+++E+ Q+ + +D +SG+D+T L ++A+LGPIR L+   +  ++  
Sbjct: 484 LLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSAS 543

Query: 635 QVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFG 671
           ++R I   DF  + + ++ SVSP+ LE Y  WNK FG
Sbjct: 544 EMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFG 580


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score =  336 bits (862), Expect = 4e-92
 Identities = 174/397 (43%), Positives = 254/397 (63%), Gaps = 17/397 (4%)

Query: 277 ACSKTEDNGPKEDSSLPTFKTAKEQLWVDQQKKYHQPQRASGSSYGGVKKSLGASRSRGI 336
           A  K +D      +SLP  KT  +         +  P  +  S   GVK+  G       
Sbjct: 231 AVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPSYSGLSMVSGVKQGSG------- 283

Query: 337 LGKFVPPIPKQDGGEQNGGMQCKPYGAGPTEPAHPVDE--RLKNLEPKMIELIMNEIMDH 394
                 P P    G        KP  + PT       +    +N++  +  LIMNEI+D+
Sbjct: 284 ------PAPTTHKGTPKTNRTNKP--STPTTATRKKKDLKNFRNVDSNLANLIMNEIVDN 335

Query: 395 GPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCI 454
           G  V ++DIAG + AK  ++EIV+ P LRP++FTGLR P +G+LLFGPPG GKT++ K +
Sbjct: 336 GTAVKFDDIAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAV 395

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A++S ATFF+ISA+SLTSK+VGEGEK+VRALFAVAR  QP++IFIDE+DSLL +R +GEH
Sbjct: 396 AAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGEH 455

Query: 515 ESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARK 574
           ++SRR+KTEFL++ DG  ++ +DR+LV+GATNRPQE+DEA  RR +KR+Y+ LP    R 
Sbjct: 456 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLRRFIKRVYVSLPNEETRL 515

Query: 575 QIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPD 634
            ++ NL+ K+   L+++E+ Q+ + +D +SG+D+T L ++A+LGPIR L+   +  ++  
Sbjct: 516 LLLKNLLCKQGSPLTQKELAQLARMTDGYSGSDLTALAKDAALGPIRELKPEQVKNMSAS 575

Query: 635 QVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFG 671
           ++R I   DF  + + ++ SVSP+ LE Y  WNK FG
Sbjct: 576 EMRNIRLSDFTESLKKIKRSVSPQTLEAYIRWNKDFG 612


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  254 bits (650), Expect = 1e-67
 Identities = 136/301 (45%), Positives = 200/301 (66%), Gaps = 14/301 (4%)

Query: 383 MIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGP 442
           ++E +  +I+   P ++W+DIA +E AK  ++E VV PM  PD F G+R P KG+L+ GP
Sbjct: 190 LVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGP 249

Query: 443 PGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEI 502
           PGTGKT++ K +A++ G TFF++S+S+LTSK+ GE EK+VR LF +AR   P  IFIDEI
Sbjct: 250 PGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEI 309

Query: 503 DSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSED-----RILVVGATNRPQEIDEAAR 556
           DS+ S+RG   EHE+SRR+K+E L+Q+DG   + E+      ++V+ ATN P +IDEA R
Sbjct: 310 DSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALR 369

Query: 557 RRLVKRLYIPLPEASARKQIV-INLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREA 615
           RRL KR+YIPLP A  R +++ INL   E     + ++E I ++ + +SGAD+T +CR+A
Sbjct: 370 RRLEKRIYIPLPTAKGRAELLKINLREVE--LDPDIQLEDIAEKIEGYSGADITNVCRDA 427

Query: 616 SLGPIR----SLQTADIATITPDQVR-PIAYIDFENAFRTVRPSVSPKDLELYENWNKTF 670
           SL  +R     L   +I  ++ ++++ P+   DFE A + +  SVS  DLE YE W   F
Sbjct: 428 SLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKWMVEF 487

Query: 671 G 671
           G
Sbjct: 488 G 488


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  254 bits (650), Expect = 1e-67
 Identities = 136/301 (45%), Positives = 200/301 (66%), Gaps = 14/301 (4%)

Query: 383 MIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGP 442
           ++E +  +I+   P ++W+DIA +E AK  ++E VV PM  PD F G+R P KG+L+ GP
Sbjct: 190 LVEALERDIVSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGP 249

Query: 443 PGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEI 502
           PGTGKT++ K +A++ G TFF++S+S+LTSK+ GE EK+VR LF +AR   P  IFIDEI
Sbjct: 250 PGTGKTMLAKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEI 309

Query: 503 DSLLSQRG-DGEHESSRRIKTEFLVQLDGATTSSED-----RILVVGATNRPQEIDEAAR 556
           DS+ S+RG   EHE+SRR+K+E L+Q+DG   + E+      ++V+ ATN P +IDEA R
Sbjct: 310 DSICSRRGTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALR 369

Query: 557 RRLVKRLYIPLPEASARKQIV-INLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREA 615
           RRL KR+YIPLP A  R +++ INL   E     + ++E I ++ + +SGAD+T +CR+A
Sbjct: 370 RRLEKRIYIPLPTAKGRAELLKINLREVE--LDPDIQLEDIAEKIEGYSGADITNVCRDA 427

Query: 616 SLGPIR----SLQTADIATITPDQVR-PIAYIDFENAFRTVRPSVSPKDLELYENWNKTF 670
           SL  +R     L   +I  ++ ++++ P+   DFE A + +  SVS  DLE YE W   F
Sbjct: 428 SLMAMRRRINGLSPEEIRALSKEELQMPVTKGDFELALKKIAKSVSAADLEKYEKWMVEF 487

Query: 671 G 671
           G
Sbjct: 488 G 488


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  253 bits (647), Expect = 3e-67
 Identities = 144/338 (42%), Positives = 205/338 (60%), Gaps = 24/338 (7%)

Query: 351 EQNGGMQCKPYGAGPTEPAHPVDERLKNL--EPKMIELIMNEIMDHGPPVNWEDIAGVEF 408
           EQN G + K     P     P   +  +   +  ++E +  +I+   P V W+DIA +  
Sbjct: 159 EQNKGREEK--NKSPAAVTEPETNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVE 216

Query: 409 AKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISAS 468
           AK  +KE VV PM  P+ F G+R P KG+L+ GPPGTGKTL+ K +A++   TFF++S+S
Sbjct: 217 AKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSS 276

Query: 469 SLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG-EHESSRRIKTEFLVQ 527
           +LTSK+ GE EK+VR LF +AR   PA IFIDEIDS+ S+RG   EHE+SRR+K E LVQ
Sbjct: 277 TLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSEEHEASRRVKAELLVQ 336

Query: 528 LDGATTSSED-----RILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMS 582
           +DG   +SE+      ++V+ ATN P +IDEA RRRL KR+YIPLP A  R+++ + +  
Sbjct: 337 MDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRRRLEKRIYIPLPSAKGREEL-LRISL 395

Query: 583 KEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVR----- 637
           +E     + ++  I +  + +SGAD+T +CR+ASL  +R      I  +TP+++R     
Sbjct: 396 RELELADDVDLASIAENMEGYSGADITNVCRDASLMAMR----RRIEGLTPEEIRNLSKE 451

Query: 638 ----PIAYIDFENAFRTVRPSVSPKDLELYENWNKTFG 671
               P    DFE A + V  SVS  D+E YE W   FG
Sbjct: 452 EMHMPTTMEDFEMALKKVSKSVSAADIERYEKWIFEFG 489


>gi|116292174 fidgetin-like 2 [Homo sapiens]
          Length = 653

 Score =  244 bits (622), Expect = 2e-64
 Identities = 144/411 (35%), Positives = 223/411 (54%), Gaps = 38/411 (9%)

Query: 286 PKEDSSLPTFKTAKEQLWVDQQKKY-HQPQRA---SGSSYGGVKKSLGASRSRGILGKFV 341
           P  +S L   + A ++    + +KY ++P +A    G+SY       G  R  G   K  
Sbjct: 257 PGAESGLSLKRKAADEGPEGRYRKYAYEPAKAPVADGASYPAADN--GECRGNGFRAK-P 313

Query: 342 PPIPKQDGGEQNGGMQCKPYGA---GPT-EP---------------AHPVDERLKNLEPK 382
           P   ++  G+  GG+  K  G+   GP  EP               A P  E  K ++P 
Sbjct: 314 PGAAEEASGKYGGGVPLKVLGSPVYGPQLEPFEKFPERAPAPRGGFAVPSGETPKGVDPG 373

Query: 383 MIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFGP 442
            +EL+ ++++D GPPV W D+AG    KA ++E +VWP+LRP  + G   PP+ +LLFGP
Sbjct: 374 ALELVTSKMVDCGPPVQWADVAGQGALKAALEEELVWPLLRPPAYPGSLRPPRTVLLFGP 433

Query: 443 PGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEI 502
            G GK L+G+C+A+Q GAT   +  ++L +    EG ++++A FA ARC+ P+V+ I E+
Sbjct: 434 RGAGKALLGRCLATQLGATLLRLRGATLAAPGAAEGARLLQAAFAAARCRPPSVLLISEL 493

Query: 503 DSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKR 562
           ++LL  R DG   +   ++   L  LDG   +  D +LVVG T+RP  +DEA RRR   R
Sbjct: 494 EALLPARDDGA-AAGGALQVPLLACLDGGCGAGADGVLVVGTTSRPAALDEATRRRFSLR 552

Query: 563 LYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS 622
            Y+ LP++ AR QI+   ++++ C LSE E+  +VQ +  FSG ++ QLC++A+ G    
Sbjct: 553 FYVALPDSPARGQILQRALAQQGCALSERELAALVQGTQGFSGGELGQLCQQAAAG---- 608

Query: 623 LQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFGCG 673
                     P   RP++Y D E A   V P  S K+L+ +  W+K +G G
Sbjct: 609 -------AGLPGLQRPLSYKDLEAALAKVGPRASAKELDSFVEWDKMYGSG 652



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 28/95 (29%), Positives = 51/95 (53%), Gaps = 11/95 (11%)

Query: 11  LSEWQKNYFAITSGICTGPKADAYRAQI-----LRIQYAWANSEISQVCATKLFKKYAEK 65
           L++W + +  ++S   T P + A++ ++      R  YAWA+ +IS + A+ L K+YAEK
Sbjct: 11  LNQWPEQHLDVSS---TTP-SPAHKLELPPGGRQRCHYAWAHDDISALTASNLLKRYAEK 66

Query: 66  YSAIIDSDNVESGLNNYAENILTLAGSQQTDSDKW 100
           YS ++DS      L  Y++   +     + D + W
Sbjct: 67  YSGVLDSPYERPALGGYSD--ASFLNGAKGDPEPW 99


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score =  226 bits (576), Expect = 5e-59
 Identities = 117/246 (47%), Positives = 168/246 (68%), Gaps = 2/246 (0%)

Query: 382 KMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFG 441
           K+   +   I+   P V W D+AG+E AK  +KE V+ P+  P +FTG R P +GILLFG
Sbjct: 115 KLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFG 174

Query: 442 PPGTGKTLIGKCIASQSG-ATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFID 500
           PPGTGK+ + K +A+++  +TFFSIS+S L SKW+GE EK+V+ LF +AR  +P++IFID
Sbjct: 175 PPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFID 234

Query: 501 EIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLV 560
           EIDSL   R + E E++RRIKTEFLVQ+ G    + D ILV+GATN P  +D A RRR  
Sbjct: 235 EIDSLCGSRSENESEAARRIKTEFLVQMQGVGVDN-DGILVLGATNIPWVLDSAIRRRFE 293

Query: 561 KRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPI 620
           KR+YIPLPE  AR  +    +   Q  L+E +  ++ +++D +SGAD++ + R+A + P+
Sbjct: 294 KRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPV 353

Query: 621 RSLQTA 626
           R +Q+A
Sbjct: 354 RKVQSA 359


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score =  225 bits (574), Expect = 9e-59
 Identities = 112/246 (45%), Positives = 171/246 (69%), Gaps = 2/246 (0%)

Query: 382 KMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFG 441
           K+ E +M  ++   P + W D+AG+E AK  +KE V+ P+  P +FTG R P +GILLFG
Sbjct: 108 KLQEQLMGAVVMEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFG 167

Query: 442 PPGTGKTLIGKCIASQSG-ATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFID 500
           PPGTGK+ + K +A+++  +TFFS+S+S L SKW+GE EK+V+ LF +AR  +P++IFID
Sbjct: 168 PPGTGKSYLAKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFID 227

Query: 501 EIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLV 560
           E+DSL   R + E E++RRIKTEFLVQ+ G   ++ D  LV+GATN P  +D A RRR  
Sbjct: 228 EVDSLCGSRNENESEAARRIKTEFLVQMQG-VGNNNDGTLVLGATNIPWVLDSAIRRRFE 286

Query: 561 KRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPI 620
           KR+YIPLPE +AR Q+    +      L++  I ++ ++++ +SGAD++ + R++ + P+
Sbjct: 287 KRIYIPLPEEAARAQMFRLHLGSTPHNLTDANIHELARKTEGYSGADISIIVRDSLMQPV 346

Query: 621 RSLQTA 626
           R +Q+A
Sbjct: 347 RKVQSA 352


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score =  223 bits (569), Expect = 3e-58
 Identities = 123/307 (40%), Positives = 192/307 (62%), Gaps = 24/307 (7%)

Query: 382 KMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPKGILLFG 441
           ++  ++  +I  H P + W DI G++ AK  +KE VV+P+  P +FTG+  P KG+LL+G
Sbjct: 163 ELAAVVSRDIYLHNPNIKWNDIIGLDAAKQLVKEAVVYPIRYPQLFTGILSPWKGLLLYG 222

Query: 442 PPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDE 501
           PPGTGKTL+ K +A++   TFF+ISAS++ SKW G+ EK+VR LF +AR   P+ IF+DE
Sbjct: 223 PPGTGKTLLAKAVATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDE 282

Query: 502 IDSLLSQRG---DGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRR 558
           ++S++SQRG    GEHE S R+KTE LVQ+DG    SED + V+ A+N P E+D A  RR
Sbjct: 283 LESVMSQRGTASGGEHEGSLRMKTELLVQMDG-LARSEDLVFVLAASNLPWELDCAMLRR 341

Query: 559 LVKRLYIPLPEASARKQIVINLM---SKEQCCLSEEEIEQIV--QQSDAFSGADMTQLCR 613
           L KR+ + LP   AR+ ++ + +   SK +      E+E  V  Q+++ +SG+D+  +CR
Sbjct: 342 LEKRILVDLPSREARQAMIYHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCR 401

Query: 614 EASLGPIRSL---------QTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDL-ELY 663
           EA++ P+R +         +++D+  I   Q+  +   DF +     +PS   K+L + Y
Sbjct: 402 EAAMRPVRKIFDALENHQSESSDLPRI---QLDIVTTADFLDVLTHTKPSA--KNLAQRY 456

Query: 664 ENWNKTF 670
            +W + F
Sbjct: 457 SDWQREF 463


>gi|31377644 ATPase family, AAA domain containing 1 [Homo sapiens]
          Length = 361

 Score =  191 bits (486), Expect = 1e-48
 Identities = 95/260 (36%), Positives = 159/260 (61%), Gaps = 4/260 (1%)

Query: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR--GPPKGILLFGPPGTGKTLIGKCIA 455
           V W DIAG++     +K+ V+ P+ +  +F   R   PPKG+LL+GPPG GKTLI K  A
Sbjct: 88  VTWSDIAGLDDVITDLKDTVILPIKKKHLFENSRLLQPPKGVLLYGPPGCGKTLIAKATA 147

Query: 456 SQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHE 515
            ++G  F ++  S+LT KW GE +K+  A+F++A   QP++IFIDEIDS L  R   +HE
Sbjct: 148 KEAGCRFINLQPSTLTDKWYGESQKLAAAVFSLAIKLQPSIIFIDEIDSFLRNRSSSDHE 207

Query: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQ 575
           ++  +K +F+   DG  T    +++V+GATNRPQ++D A  RR+  R +I  P A  +++
Sbjct: 208 ATAMMKAQFMSLWDGLDTDHSCQVIVMGATNRPQDLDSAIMRRMPTRFHINQP-ALKQRE 266

Query: 576 IVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS-LQTADIATITPD 634
            ++ L+ K +      ++ ++ Q++D FSG+D+ ++CR+A+L  +R  + +    +   D
Sbjct: 267 AILKLILKNENVDRHVDLLEVAQETDGFSGSDLKEMCRDAALLCVREYVNSTSEESHDED 326

Query: 635 QVRPIAYIDFENAFRTVRPS 654
           ++RP+   D   A   ++ S
Sbjct: 327 EIRPVQQQDLHRAIEKMKKS 346


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  177 bits (448), Expect = 4e-44
 Identities = 101/289 (34%), Positives = 160/289 (55%), Gaps = 18/289 (6%)

Query: 388 MNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTG 446
           M EI    P V+W DI G+E  K  +++ V WP+  P+ F  +   PPKG+LL+GPPG  
Sbjct: 614 MREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCS 673

Query: 447 KTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLL 506
           KT+I K +A++SG  F +I    L +K+VGE E+ VR  F  AR   P++IF DE+D+L 
Sbjct: 674 KTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALA 733

Query: 507 SQRGD--GEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKR 562
            +RG   G    + R+  + L ++DG     +  + ++ ATNRP  ID+A  R  R+ + 
Sbjct: 734 VERGSSLGAGNVADRVLAQLLTEMDGIEQLKD--VTILAATNRPDRIDKALMRPGRIDRI 791

Query: 563 LYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS 622
           +Y+PLP+A+ R++I   L        +E ++++++ Q+DA+SGA++  +CREA+L     
Sbjct: 792 IYVPLPDAATRREI-FKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAAL----- 845

Query: 623 LQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTFG 671
                +A     Q   I    F  A  TV P +       YE++ +  G
Sbjct: 846 -----LALEEDIQANLIMKRHFTQALSTVTPRIPESLRRFYEDYQEKSG 889



 Score =  159 bits (402), Expect = 8e-39
 Identities = 92/263 (34%), Positives = 149/263 (56%), Gaps = 6/263 (2%)

Query: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKCIAS 456
           V ++ I G+      I+EI+  P+ +P++F     P P+G+LL+GPPGTGKT+I + +A+
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVAN 409

Query: 457 QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHES 516
           + GA    I+   + SK+ GE E  +R +FA A  + P++IFIDE+D+L  +R   ++E 
Sbjct: 410 EVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEV 469

Query: 517 SRRIKTEFLVQLDG-ATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASAR 573
            +R+    L  +DG  +  SE ++LV+GATNRP  +D A RR  R  K + I +P A  R
Sbjct: 470 EKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQDR 529

Query: 574 KQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSL--QTADIATI 631
             I+  L+ +    L+E E+ Q+   +  + GAD+  LC EA L  +R +  +  ++  +
Sbjct: 530 LDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPNLPDV 589

Query: 632 TPDQVRPIAYIDFENAFRTVRPS 654
               +  I   DF  A   +RPS
Sbjct: 590 KVAGLVKITLKDFLQAMNDIRPS 612


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  169 bits (429), Expect = 6e-42
 Identities = 106/301 (35%), Positives = 158/301 (52%), Gaps = 22/301 (7%)

Query: 388 MNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGL-RGPPKGILLFGPPGTG 446
           + E +   P V WEDI G+E  K  ++E+V +P+  PD F      P KG+L +GPPG G
Sbjct: 464 LRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCG 523

Query: 447 KTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLL 506
           KTL+ K IA++  A F SI    L + W GE E  VR +F  AR   P V+F DE+DS+ 
Sbjct: 524 KTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIA 583

Query: 507 SQRGDGEHE---SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVK 561
             RG    +   ++ R+  + L ++DG +T  +  + ++GATNRP  ID A  R  RL +
Sbjct: 584 KARGGNIGDGGGAADRVINQILTEMDGMST--KKNVFIIGATNRPDIIDPAILRPGRLDQ 641

Query: 562 RLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621
            +YIPLP+  +R  I+   + K      + ++E + + ++ FSGAD+T++C+ A    IR
Sbjct: 642 LIYIPLPDEKSRVAILKANLRKSPVA-KDVDLEFLAKMTNGFSGADLTEICQRACKLAIR 700

Query: 622 SLQTADIATITPDQVRP-------------IAYIDFENAFRTVRPSVSPKDLELYENWNK 668
               ++I      Q  P             I    FE A R  R SVS  D+  YE + +
Sbjct: 701 ESIESEIRRERERQTNPSAMEVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQ 760

Query: 669 T 669
           T
Sbjct: 761 T 761



 Score =  156 bits (394), Expect = 7e-38
 Identities = 103/293 (35%), Positives = 154/293 (52%), Gaps = 27/293 (9%)

Query: 343 PIPKQDGGEQNGGMQCKPYGAGPTEPA-----------HPVDERLKNLEPKMIELIMNEI 391
           PI K D     GGM+   +    T+P+           H   E +K  +    E  +NE 
Sbjct: 145 PIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDTVIHCEGEPIKREDE---EESLNE- 200

Query: 392 MDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLI 450
                 V ++DI G     A IKE+V  P+  P +F  +   PP+GILL+GPPGTGKTLI
Sbjct: 201 ------VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLI 254

Query: 451 GKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRG 510
            + +A+++GA FF I+   + SK  GE E  +R  F  A    PA+IFIDE+D++  +R 
Sbjct: 255 ARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKRE 314

Query: 511 DGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLP 568
               E  RRI ++ L  +DG        ++V+ ATNRP  ID A RR  R  + + I +P
Sbjct: 315 KTHGEVERRIVSQLLTLMDG--LKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIP 372

Query: 569 EASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621
           +A+ R +I + + +K      + ++EQ+  ++    GAD+  LC EA+L  IR
Sbjct: 373 DATGRLEI-LQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIR 424


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  160 bits (406), Expect = 3e-39
 Identities = 105/320 (32%), Positives = 168/320 (52%), Gaps = 34/320 (10%)

Query: 374 ERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-G 432
           E  KN++P     ++  +MD   PV+WE+I G+E  K  +K+ + WP+  P  F  +   
Sbjct: 439 EAFKNIQPSSFRSVIG-LMDI-KPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLT 496

Query: 433 PPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQ 492
            PKG+LL+GPPG  KT + + +A+    +F S+S + L S +VG+ EK++  +F  AR  
Sbjct: 497 QPKGVLLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARAS 556

Query: 493 QPAVIFIDEIDSLLSQRGDGEH--ESSRRIKTEFLVQLDGATTSSEDR------------ 538
            PA++F+DEIDS+L  R   +   +   R+ +  L +LDG    + +R            
Sbjct: 557 TPAILFLDEIDSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQE 616

Query: 539 -----ILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE 591
                ++++ ATNRP  +D A  R  RL K +YIP P+   R  I + + +K      + 
Sbjct: 617 VFNRSVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSI-LKVCTKTMPIGPDV 675

Query: 592 EIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651
            +E +  ++  FSGAD+  LC EA+L  ++     D  T+  +         F  + +TV
Sbjct: 676 SLENLAAETCFFSGADLRNLCTEAALLALQE-NGLDATTVKQEH--------FLKSLKTV 726

Query: 652 RPSVSPKDLELYENWNKTFG 671
           +PS+S KDL LYEN  K  G
Sbjct: 727 KPSLSCKDLALYENLFKKEG 746



 Score =  131 bits (329), Expect = 2e-30
 Identities = 88/259 (33%), Positives = 144/259 (55%), Gaps = 20/259 (7%)

Query: 403 IAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCIASQSGAT 461
           + G+  A  +++E++  P+  P   T L    P+G+LL GPPG GKT + + +A ++GA 
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261

Query: 462 FFSISASSLTSKWVGEGEKMVRALFAVAR---CQQPAVIFIDEIDSLLSQRGDGEHESSR 518
             ++SA +L     GE E+ VR +F  AR    + P+++F+DE+D+L  QRG    ES  
Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQRGSRAPES-- 319

Query: 519 RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASARKQI 576
           R+  + L  LDGA  S +  ++VVGATNRP  +D A RR  R  + + I  P    RK+I
Sbjct: 320 RVVAQVLTLLDGA--SGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEI 377

Query: 577 VINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIATITPDQV 636
            + +++ +    S  ++  + + +  + GAD+T LCREA++  +   +         +Q 
Sbjct: 378 -LQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSE--------KNQD 428

Query: 637 RP-IAYIDFENAFRTVRPS 654
            P I  IDF  AF+ ++PS
Sbjct: 429 NPVIDEIDFLEAFKNIQPS 447


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  154 bits (388), Expect = 3e-37
 Identities = 96/276 (34%), Positives = 151/276 (54%), Gaps = 10/276 (3%)

Query: 396 PPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCI 454
           P V W DI  +E  +  +   ++ P+  PD F  L    P G+LL GPPG GKTL+ K +
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A++SG  F S+    L + +VGE E+ VR +F  A+   P VIF DE+D+L  +R D E 
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 515 ESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASA 572
            +S R+  + L ++DG    +  ++ ++ ATNRP  ID A  R  RL K L++ LP  + 
Sbjct: 590 GASVRVVNQLLTEMDG--LEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 647

Query: 573 RKQIV--INLMSKEQCCLSEEEIEQIV--QQSDAFSGADMTQLCREASLGPIRSLQTADI 628
           R  I+  I     +    ++  +E I    + D ++GAD++ L REAS+  +R       
Sbjct: 648 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQK 707

Query: 629 ATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYE 664
           +     +++ +++  FE AF+ VR S+S KD  +YE
Sbjct: 708 SGNEKGELK-VSHKHFEEAFKKVRSSISKKDQIMYE 742



 Score =  121 bits (303), Expect = 2e-27
 Identities = 76/226 (33%), Positives = 124/226 (54%), Gaps = 10/226 (4%)

Query: 398 VNWEDIAGVEFAKATIKEI--VVWPMLRPDIFTGLRG-PPKGILLFGPPGTGKTLIGKCI 454
           V +ED+ G +    T+KE+  ++  M  P+++  L   PP+G+LL GPPG GKTL+   I
Sbjct: 156 VKFEDVGGNDM---TLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAI 212

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A +       ++A  + S   GE E+ +R LF  A    P +IFIDEID++  +R     
Sbjct: 213 AGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASK 272

Query: 515 ESSRRIKTEFLVQLDGA-TTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEAS 571
           +  RRI  + L  +D     ++  R+LV+GATNRP  +D A RR  R  + + + +P+ +
Sbjct: 273 DMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEA 332

Query: 572 ARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617
           +R++I+  L  K +      +   +   +  F GAD+  LCREA++
Sbjct: 333 SRERILQTLCRKLR-LPQAFDFCHLAHLTPGFVGADLMALCREAAM 377


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  154 bits (388), Expect = 3e-37
 Identities = 96/276 (34%), Positives = 151/276 (54%), Gaps = 10/276 (3%)

Query: 396 PPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCI 454
           P V W DI  +E  +  +   ++ P+  PD F  L    P G+LL GPPG GKTL+ K +
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A++SG  F S+    L + +VGE E+ VR +F  A+   P VIF DE+D+L  +R D E 
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 515 ESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASA 572
            +S R+  + L ++DG    +  ++ ++ ATNRP  ID A  R  RL K L++ LP  + 
Sbjct: 696 GASVRVVNQLLTEMDG--LEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 753

Query: 573 RKQIV--INLMSKEQCCLSEEEIEQIV--QQSDAFSGADMTQLCREASLGPIRSLQTADI 628
           R  I+  I     +    ++  +E I    + D ++GAD++ L REAS+  +R       
Sbjct: 754 RLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQK 813

Query: 629 ATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYE 664
           +     +++ +++  FE AF+ VR S+S KD  +YE
Sbjct: 814 SGNEKGELK-VSHKHFEEAFKKVRSSISKKDQIMYE 848



 Score =  121 bits (303), Expect = 2e-27
 Identities = 76/226 (33%), Positives = 124/226 (54%), Gaps = 10/226 (4%)

Query: 398 VNWEDIAGVEFAKATIKEI--VVWPMLRPDIFTGLRG-PPKGILLFGPPGTGKTLIGKCI 454
           V +ED+ G +    T+KE+  ++  M  P+++  L   PP+G+LL GPPG GKTL+   I
Sbjct: 262 VKFEDVGGNDM---TLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAI 318

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A +       ++A  + S   GE E+ +R LF  A    P +IFIDEID++  +R     
Sbjct: 319 AGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASK 378

Query: 515 ESSRRIKTEFLVQLDGA-TTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEAS 571
           +  RRI  + L  +D     ++  R+LV+GATNRP  +D A RR  R  + + + +P+ +
Sbjct: 379 DMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEA 438

Query: 572 ARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617
           +R++I+  L  K +      +   +   +  F GAD+  LCREA++
Sbjct: 439 SRERILQTLCRKLR-LPQAFDFCHLAHLTPGFVGADLMALCREAAM 483


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  151 bits (381), Expect = 2e-36
 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437
           L P+    IM    D  P V + DI G++  K  ++E V  P+   +++  +   PP+G+
Sbjct: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198

Query: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497
           L++GPPG GKT++ K +A  + A F  +  S    K++GEG +MVR +F +A+   PA+I
Sbjct: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258

Query: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554
           FIDEID++ ++R D +  + R   RI  E L Q+DG        + V+ ATNR   +D A
Sbjct: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 316

Query: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611
             R  RL +++  PLP+   ++ I   + SK    LSEE ++E  V + D  SGAD+  +
Sbjct: 317 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 374

Query: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651
           C+E+ +  +R  +   +A             DFE A++TV
Sbjct: 375 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 402


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  151 bits (381), Expect = 2e-36
 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437
           L P+    IM    D  P V + DI G++  K  ++E V  P+   +++  +   PP+G+
Sbjct: 112 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 171

Query: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497
           L++GPPG GKT++ K +A  + A F  +  S    K++GEG +MVR +F +A+   PA+I
Sbjct: 172 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 231

Query: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554
           FIDEID++ ++R D +  + R   RI  E L Q+DG        + V+ ATNR   +D A
Sbjct: 232 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 289

Query: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611
             R  RL +++  PLP+   ++ I   + SK    LSEE ++E  V + D  SGAD+  +
Sbjct: 290 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 347

Query: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651
           C+E+ +  +R  +   +A             DFE A++TV
Sbjct: 348 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 375


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  151 bits (381), Expect = 2e-36
 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437
           L P+    IM    D  P V + DI G++  K  ++E V  P+   +++  +   PP+G+
Sbjct: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202

Query: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497
           L++GPPG GKT++ K +A  + A F  +  S    K++GEG +MVR +F +A+   PA+I
Sbjct: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262

Query: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554
           FIDEID++ ++R D +  + R   RI  E L Q+DG        + V+ ATNR   +D A
Sbjct: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 320

Query: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611
             R  RL +++  PLP+   ++ I   + SK    LSEE ++E  V + D  SGAD+  +
Sbjct: 321 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 378

Query: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651
           C+E+ +  +R  +   +A             DFE A++TV
Sbjct: 379 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 406


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  148 bits (373), Expect = 2e-35
 Identities = 85/237 (35%), Positives = 136/237 (57%), Gaps = 11/237 (4%)

Query: 392 MDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFT--GLRGPPKGILLFGPPGTGKTL 449
           ++  P   + DI G++     IKE V  P+  P+ +   G++ PPKG++L+GPPGTGKTL
Sbjct: 176 VEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIK-PPKGVILYGPPGTGKTL 234

Query: 450 IGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQR 509
           + K +A+Q+ ATF  +  S L  K++G+G K+VR LF VA    P+++FIDEID++ ++R
Sbjct: 235 LAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKR 294

Query: 510 GDGEHESSRRIK---TEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLY 564
            D      R I+    E L QLDG    S   + V+ ATNR + +D A  R  R+ +++ 
Sbjct: 295 YDSNSGGEREIQRTMLELLNQLDG--FDSRGDVKVIMATNRIETLDPALIRPGRIDRKIE 352

Query: 565 IPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621
            PLP+   +K+I   + +       +  ++ ++   D  SGAD+  +C EA L  +R
Sbjct: 353 FPLPDEKTKKRI-FQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALR 408


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  146 bits (369), Expect = 5e-35
 Identities = 87/239 (36%), Positives = 137/239 (57%), Gaps = 11/239 (4%)

Query: 392 MDHGPP--VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKT 448
           M H  P  V++ +I G+      ++E++  P+  P++F  +   PPKG LL+GPPGTGKT
Sbjct: 136 MSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKT 195

Query: 449 LIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQ 508
           L+ + +ASQ    F  + +SS+  K++GE  +++R +F  AR  QP +IF+DEID++  +
Sbjct: 196 LLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGR 255

Query: 509 R---GDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRL 563
           R   G       +R   E L Q+DG  T    R+ ++ ATNRP  +D A  R  RL +++
Sbjct: 256 RFSEGTSADREIQRTLMELLNQMDGFDTL--HRVKMIMATNRPDTLDPALLRPGRLDRKI 313

Query: 564 YIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRS 622
           +I LP   AR  I + + +       E + E IV+ SD F+GAD+  +C EA +  IR+
Sbjct: 314 HIDLPNEQARLDI-LKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRA 371


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  144 bits (364), Expect = 2e-34
 Identities = 97/296 (32%), Positives = 151/296 (51%), Gaps = 21/296 (7%)

Query: 377 KNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPK 435
           K L  K+  L+   +++  P   +E I G++     IKE++  P+  P++F  L    PK
Sbjct: 125 KILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPK 184

Query: 436 GILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPA 495
           G+LL+GPPGTGKTL+ + +A  +  TF  +S S L  K++GEG +MVR LF +AR   P+
Sbjct: 185 GVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPS 244

Query: 496 VIFIDEIDSLLSQR---GDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEID 552
           +IF+DEIDS+ S R   G G     +R   E L QLDG   +    I V+ ATNR   +D
Sbjct: 245 IIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATK--NIKVIMATNRIDILD 302

Query: 553 EAARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQ 610
            A  R  R+ +++  P P   AR  I + + S++        + +I +     SGA++  
Sbjct: 303 SALLRPGRIDRKIEFPPPNEEARLDI-LKIHSRKMNLTRGINLRKIAELMPGASGAEVKG 361

Query: 611 LCREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENW 666
           +C EA +  +R  +              +   DFE A   V    S K++ + + W
Sbjct: 362 VCTEAGMYALRERRV------------HVTQEDFEMAVAKVMQKDSEKNMSIKKLW 405


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  140 bits (353), Expect = 4e-33
 Identities = 88/263 (33%), Positives = 146/263 (55%), Gaps = 24/263 (9%)

Query: 365 PTEPAHPVDERLKNLEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRP 424
           PTE     D R+K +E           +D  P   + DI G++     + E +V PM   
Sbjct: 165 PTE----YDSRVKAME-----------VDERPTEQYSDIGGLDKQIQELVEAIVLPMNHK 209

Query: 425 DIFTGLR-GPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVR 483
           + F  L   PPKG+L++GPPGTGKTL+ +  A+Q+ ATF  ++   L   ++G+G K+VR
Sbjct: 210 EKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVR 269

Query: 484 ALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIK---TEFLVQLDGATTSSEDRIL 540
             FA+A+ + P++IFIDE+D++ ++R D E    R ++    E L QLDG   +++  + 
Sbjct: 270 DAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQ--VK 327

Query: 541 VVGATNRPQEIDEAARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQ 598
           V+ ATNR   +D A  R  RL +++  P+P   AR +I + + S++     +   E++ +
Sbjct: 328 VIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARI-MQIHSRKMNVSPDVNYEELAR 386

Query: 599 QSDAFSGADMTQLCREASLGPIR 621
            +D F+GA    +C EA +  +R
Sbjct: 387 CTDDFNGAQCKAVCVEAGMIALR 409


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  139 bits (351), Expect = 7e-33
 Identities = 85/250 (34%), Positives = 134/250 (53%), Gaps = 9/250 (3%)

Query: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437
           L PK+   +    ++  P V + D+ G +     ++E+V  P+L P+ F  L   PPKG+
Sbjct: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212

Query: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497
           LLFGPPGTGKTL  + +A+++ A F  +  S L  K+VGEG +MVR LF +AR ++  +I
Sbjct: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272

Query: 498 FIDEIDSLLSQR---GDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554
           F DEID++   R   G G     +R   E + QLDG       ++L+  ATNRP  +D A
Sbjct: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLM--ATNRPDTLDPA 330

Query: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLC 612
             R  RL +++   LP+   R  I   + ++      +   E + +     +GA++  +C
Sbjct: 331 LMRPGRLDRKIEFSLPDLEGRTHI-FKIHARSMSVERDIRFELLARLCPNSTGAEIRSVC 389

Query: 613 REASLGPIRS 622
            EA +  IR+
Sbjct: 390 TEAGMFAIRA 399


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  137 bits (344), Expect = 4e-32
 Identities = 83/232 (35%), Positives = 124/232 (53%), Gaps = 10/232 (4%)

Query: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCIAS 456
           V ++ I G+      +KE+VV+P+L P+IF   +  PP+G L +GPPGTGKTL+ + +A+
Sbjct: 397 VRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALAN 456

Query: 457 QSG-----ATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGD 511
           +         FF    +   SKWVGE E+ +R LF  A   +P++IF DEID L   R  
Sbjct: 457 ECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSS 516

Query: 512 GEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPE 569
            + +    I +  L  +DG     E  I+V+GATNR   ID A RR  R  +     LP+
Sbjct: 517 RQDQIHSSIVSTLLALMDGLDNRGE--IVVIGATNRLDSIDPALRRPGRFDREFLFNLPD 574

Query: 570 ASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621
             ARK I+          LS+  + ++ ++   + GAD+  LC EA+L  +R
Sbjct: 575 QKARKHILQIHTRDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALR 626


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  135 bits (341), Expect = 9e-32
 Identities = 80/232 (34%), Positives = 125/232 (53%), Gaps = 10/232 (4%)

Query: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGILLFGPPGTGKTLIGKCIAS 456
           V ++ + G+    A +KE+VV+P+L P++F   +  PP+G L +GPPGTGKTL+ + +A+
Sbjct: 423 VRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALAN 482

Query: 457 QSG-----ATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGD 511
           +         FF    +   SKWVGE E+ +R LF  A   +P++IF DEID L   R  
Sbjct: 483 ECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSS 542

Query: 512 GEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPE 569
            + +    I +  L  +DG  +  E  I+V+GATNR   ID A RR  R  +     LP+
Sbjct: 543 RQDQIHSSIVSTLLALMDGLDSRGE--IVVIGATNRLDSIDPALRRPGRFDREFLFSLPD 600

Query: 570 ASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIR 621
             ARK+I+            +  +E++ +    + GAD+  +C EA+L  +R
Sbjct: 601 KEARKEILKIHTRDWNPKPLDTFLEELAENCVGYCGADIKSICAEAALCALR 652


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  132 bits (331), Expect = 1e-30
 Identities = 89/285 (31%), Positives = 145/285 (50%), Gaps = 17/285 (5%)

Query: 396 PPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFT-GLRGPPKGILLFGPPGTGKTLIGKCI 454
           P V+W D+ G++  K  I E +  P+  P++ + GLR    G+LL GPPGTGKTL+ K +
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLSLGLRR--SGLLLHGPPGTGKTLLAKAV 757

Query: 455 ASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEH 514
           A++   TF S+    L + +VG+ E+ VR +FA AR   P +IF DE+DSL   RG    
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 817

Query: 515 ESS--RRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEA 570
                 R+ ++ L +LDG  ++ +  + V+GATNRP  +D A  R  R  K +++   E 
Sbjct: 818 SGGVMDRVVSQLLAELDGLHSTQD--VFVIGATNRPDLLDPALLRPGRFDKLVFVGANED 875

Query: 571 SARKQIVINLMSKEQCCLSEEEIEQIVQQSDA----FSGADMTQLCREASLGPI-RSLQT 625
            A +  V++ ++++      E    +V   D      +GAD+  LC +A    + R +  
Sbjct: 876 RASQLRVLSAITRK---FKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRRVHD 932

Query: 626 ADIATITPDQVRPIAYIDFENAFRTVRPSVSPKDLELYENWNKTF 670
            +           +   D   A   ++PSVS ++L  Y+   + F
Sbjct: 933 LEEGLEPGSSALMLTMEDLLQAAARLQPSVSEQELLRYKRIQRKF 977



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 56/224 (25%), Positives = 101/224 (45%), Gaps = 10/224 (4%)

Query: 410 KATIKEI--VVWPMLRPD--IFTGLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSI 465
           +A + E+  V+ P L+P   + TG       +LL GPPG GKT +     S  G     +
Sbjct: 439 EALVSELCAVLKPRLQPGGALLTGT----SSVLLRGPPGCGKTTVVAAACSHLGLHLLKV 494

Query: 466 SASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFL 525
             SSL ++  G  E  ++A+F+ AR  +PAV+ +  +D LL +  DG  E +R +     
Sbjct: 495 PCSSLCAESSGAVETKLQAIFSRARRCRPAVLLLTAVD-LLGRDRDGLGEDARVMAVLRH 553

Query: 526 VQLDGATTSSEDRILVVGATNRPQEIDEAARRRLVKRLYIPLPEASARKQIVINLMSKEQ 585
           + L+    +S   ++VV  T+R Q++    +      L +P      R  I +  ++   
Sbjct: 554 LLLNEDPLNSCPPLMVVATTSRAQDLPADVQTAFPHELEVPALSEGQRLSI-LRALTAHL 612

Query: 586 CCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSLQTADIA 629
               E  + Q+ ++   F   D+  L   +S      ++ + +A
Sbjct: 613 PLGQEVNLAQLARRCAGFVVGDLYALLTHSSRAACTRIKNSGLA 656


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  128 bits (321), Expect = 2e-29
 Identities = 74/229 (32%), Positives = 123/229 (53%), Gaps = 6/229 (2%)

Query: 398  VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGPPK-GILLFGPPGTGKTLIGKCIAS 456
            + W+ I G+   +  + + +  P   P++F  L    + GILL+GPPGTGKTL+   IA 
Sbjct: 837  LGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIAR 896

Query: 457  QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHES 516
            +S   F S+    L SK++G  E+ VR +F  A+  +P ++F DE +S+  +RG      
Sbjct: 897  ESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGV 956

Query: 517  SRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASARK 574
            + R+  + L QLDG        + V+ AT+RP  ID A  R  RL K +Y P P+  +R 
Sbjct: 957  TDRVVNQLLTQLDG--VEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRL 1014

Query: 575  QIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASLGPIRSL 623
            +I +N++S       + +++ +   +D+F+GAD+  L   A L  +  +
Sbjct: 1015 EI-LNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGM 1062



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 69/327 (21%), Positives = 134/327 (40%), Gaps = 48/327 (14%)

Query: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPML-RP------DIFTGLR 431
           L+P + E    EI    P +    + GV     +  E +   +L RP       +  GLR
Sbjct: 532 LDPMVKEENSEEIDFILPFLKLSSLGGVNSLGVSSLEHITHSLLGRPLSRQLMSLVAGLR 591

Query: 432 GPPKGILLFGPPGTGKTLIGKCIASQS----GATFFSISASSLTSKWVGEGEKMVRALFA 487
                +LL G  G+GK+ + K I  ++     A    +   +L  K +   +K +   F+
Sbjct: 592 NG--ALLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRGKRLENIQKTLEVAFS 649

Query: 488 VARCQQPAVIFIDEIDSLLSQRGDGEHE-SSRRIKTEFLVQLDGATTS---SEDRILVVG 543
            A   QP+V+ +D++D +       EHE S   ++++ L            S   ++ + 
Sbjct: 650 EAVWMQPSVVLLDDLDLIAGLPAVPEHEHSPDAVQSQRLAHALNDMIKEFISMGSLVALI 709

Query: 544 ATNRPQE-----IDEAARRRLVKRL-YIPLPEASARKQIVINLMSKEQCC----LSEEEI 593
           AT++ Q+     +  A    + + + +I  P    R +I+ N++  +  C     ++ ++
Sbjct: 710 ATSQSQQSLHPLLVSAQGVHIFQCVQHIQPPNQEQRCEILCNVIKNKLDCDINKFTDLDL 769

Query: 594 EQIVQQSDAFSGADMTQLCREASLGPI--RSLQTADIATITPDQVRPIAYIDFENAFRTV 651
           + + +++  F   D T L   A    +  +S+ T +   +T         +DF+ A R  
Sbjct: 770 QHVAKETGGFVARDFTVLVDRAIHSRLSRQSISTREKLVLTT--------LDFQKALRGF 821

Query: 652 RPSV-------SPKDLELYENWNKTFG 671
            P+         P+DL     W+K  G
Sbjct: 822 LPASLRSVNLHKPRDL----GWDKIGG 844


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.130    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,682,917
Number of Sequences: 37866
Number of extensions: 1242002
Number of successful extensions: 2748
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 57
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 2562
Number of HSP's gapped (non-prelim): 90
length of query: 674
length of database: 18,247,518
effective HSP length: 109
effective length of query: 565
effective length of database: 14,120,124
effective search space: 7977870060
effective search space used: 7977870060
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.