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Search of human proteins with 181336739
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
(1044 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 2406 0.0
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 1494 0.0
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 892 0.0
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 724 0.0
gi|55770876 notch4 preproprotein [Homo sapiens] 316 8e-86
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 294 3e-79
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 294 3e-79
gi|134244285 Notch homolog 3 [Homo sapiens] 292 1e-78
gi|148833508 notch1 preproprotein [Homo sapiens] 285 2e-76
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 285 2e-76
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 285 2e-76
gi|24041035 notch 2 preproprotein [Homo sapiens] 278 3e-74
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 272 1e-72
gi|153946395 tenascin C precursor [Homo sapiens] 232 2e-60
gi|4557679 jagged 1 precursor [Homo sapiens] 224 4e-58
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 218 3e-56
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 217 5e-56
gi|21264602 laminin alpha 5 [Homo sapiens] 216 9e-56
gi|122937283 6720455I24Rik homolog [Homo sapiens] 216 1e-55
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 213 8e-55
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 179 1e-44
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 179 1e-44
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 178 2e-44
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 177 6e-44
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 172 1e-42
gi|143770880 laminin, beta 4 [Homo sapiens] 171 4e-42
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 164 3e-40
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 158 3e-38
gi|56237021 fibrillin 3 precursor [Homo sapiens] 152 1e-36
gi|110735443 delta-like 1 [Homo sapiens] 149 1e-35
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 2406 bits (6236), Expect = 0.0
Identities = 1044/1044 (100%), Positives = 1044/1044 (100%)
Query: 1 MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNW 60
MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNW
Sbjct: 1 MVLSLTGLIAFSFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNW 60
Query: 61 FKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHC 120
FKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHC
Sbjct: 61 FKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHC 120
Query: 121 EPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGT 180
EPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGT
Sbjct: 121 EPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGT 180
Query: 181 HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC 240
HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC
Sbjct: 181 HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC 240
Query: 241 HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDR 300
HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDR
Sbjct: 241 HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDR 300
Query: 301 CQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL 360
CQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL
Sbjct: 301 CQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL 360
Query: 361 PCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
PCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG
Sbjct: 361 PCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC
Sbjct: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
Query: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 540
PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH
Sbjct: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSH 540
Query: 541 ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 600
ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF
Sbjct: 541 ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 600
Query: 601 RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG 660
RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG
Sbjct: 601 RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG 660
Query: 661 QDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSA 720
QDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSA
Sbjct: 661 QDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSA 720
Query: 721 EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE 780
EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE
Sbjct: 721 EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCE 780
Query: 781 QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISP 840
QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISP
Sbjct: 781 QRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKISP 840
Query: 841 ALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAMRMTSTDY 900
ALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAMRMTSTDY
Sbjct: 841 ALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAMRMTSTDY 900
Query: 901 SLSGACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPES 960
SLSGACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPES
Sbjct: 901 SLSGACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPES 960
Query: 961 SYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSH 1020
SYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSH
Sbjct: 961 SYVEMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSH 1020
Query: 1021 IPGHYDLLPVRQSPANGPSQDKQS 1044
IPGHYDLLPVRQSPANGPSQDKQS
Sbjct: 1021 IPGHYDLLPVRQSPANGPSQDKQS 1044
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 1494 bits (3867), Expect = 0.0
Identities = 598/911 (65%), Positives = 720/911 (79%), Gaps = 8/911 (0%)
Query: 1 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC 54
MV+SL ++F ++ LN EDPNVCSHWESY+VTVQESY HPFDQIYYT C
Sbjct: 1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC 60
Query: 55 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS 114
TDILNWFKCTRHR+SY+TAYR G +TMYRR+SQCCPG+YESG+ C+P C ++CVHGRC++
Sbjct: 61 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA 120
Query: 115 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE 174
P+TC CEPGWGG +CSS CD DHWGPHC++RCQC+NGALCNPITGAC CAAGFRGWRCE+
Sbjct: 121 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED 180
Query: 175 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC 234
C GT+G C CQC++GA+CD GEC C PGYTG +CE+LCPPG HG CE RCPC
Sbjct: 181 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC 240
Query: 235 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA 294
QNGG CHH+TGEC+CP GW G VC QPCP G FG+NCSQ+C CH+GG CD TGQCHC+
Sbjct: 241 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
Query: 295 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH 354
GY G+RCQ+ECP G++G C++ C C NGG+C +GAC CE G+ G RC+ RLCPEGL+
Sbjct: 301 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY 360
Query: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD 414
G C CPC +NT SCHP++G C C+PGWSG +CNE+C G+YG+ CQ C+CQNGAD
Sbjct: 361 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD 420
Query: 415 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL 474
C S+TG CTCAPGF G C+ C GTYG NCSS C C N CSPVDGSCTCK GW G+
Sbjct: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
DC++ CPSGTWG CN +C C NG AC+ +DG+C+C PGW G+ CELPC DGT+GLNC+E
Sbjct: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
Query: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594
CDCSHADGC P TGHC CL GW+G+ CDS C GRWGPNCS+ C C+NG SCSP+DG C
Sbjct: 541 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC 600
Query: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC 654
ECAPGFRG CQRIC PGFYGH C+Q CP CVHSS PCHHI+G+C+CLPGF+GALCN+VC
Sbjct: 601 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC 660
Query: 655 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN 714
G FG++CA +C+C NNGTC+PID SCQC+PGWIG DCSQ CPP WGP C H C+CHN
Sbjct: 661 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN 720
Query: 715 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF 774
GA CSA DG C CTPGWTGL+CTQRCP F+GKDC +CQCQNGA CDHISG+CTCRTGF
Sbjct: 721 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF 780
Query: 775 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQA-ALMMEELN 833
G+HCEQ+C GT+GYGC+Q+C+C+NNSTCDH+TGTCYCSPG+KG RCDQA +++ LN
Sbjct: 781 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN 840
Query: 834 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM 893
++ S AL A+ + +GA+ GI++L+ +++ LL LF +R +QK K + P V+YTPAM
Sbjct: 841 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM 899
Query: 894 RMTSTDYSLSG 904
R+ + DY++SG
Sbjct: 900 RVVNADYTISG 910
Score = 149 bits (375), Expect = 2e-35
Identities = 76/138 (55%), Positives = 94/138 (68%), Gaps = 4/138 (2%)
Query: 904 GACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYV 963
GA G+DR M K KD K S +SS CSL+SSENPYATIKDPP+L K E YV
Sbjct: 994 GAFGLDRSY----MGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYV 1049
Query: 964 EMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSHIPG 1023
EMKSP SPY ++ + +++N+N+YEVEPTVSVVQ +N Q+ YDLP+NSHIP
Sbjct: 1050 EMKSPARRDSPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPC 1109
Query: 1024 HYDLLPVRQSPANGPSQD 1041
HYDLLPVR S ++ +D
Sbjct: 1110 HYDLLPVRDSSSSPKQED 1127
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 892 bits (2304), Expect = 0.0
Identities = 371/720 (51%), Positives = 455/720 (63%), Gaps = 9/720 (1%)
Query: 20 LNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRCTDILNW---FKCTRHRISYKTAYRR 76
LNP DPN CS WES+ T +ES++ PF + C W C + + Y+T YR+
Sbjct: 21 LNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCER--PWEGPHTCPQPTVVYRTVYRQ 78
Query: 77 GLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136
++T +R+R QCC G+YES FC+PLC +ECVHGRCV+P+ C C PGW G DCSS C
Sbjct: 79 VVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGWRGDDCSSECAPG 138
Query: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS 196
WGP C C C N + C+P +G C C +G + C + C PG +G CQ CQC HGA
Sbjct: 139 MWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQC-HGAP 197
Query: 197 CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGA 256
CDP+ G C C TG C+ C G+ G C CQNGG G C+CPPGW G
Sbjct: 198 CDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGT 257
Query: 257 VCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQ 316
+C+ PCP G G NCSQ+C CH+GG CD TGQC C GY GDRC+EECP G FG C++
Sbjct: 258 ICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAE 317
Query: 317 HCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVT 376
CDC +C P GAC CE G+ G RC +RLCP+G +G C PC CD ++++SCHP+
Sbjct: 318 TCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMN 377
Query: 377 GACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS 436
G C+C PGW+G HCNESCP +G GCQ C C +G C + +G C CAPG+ G CA
Sbjct: 378 GECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASL 437
Query: 437 CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCA 496
C TYG NCS+ CSC N CSP+DG C CKEGWQ +C++PCP GTWG +CN SC CA
Sbjct: 438 CPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCA 497
Query: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAG 556
+ A CSP G+C+CTPGW G C+LPCP G FG C+ CDC H+DGCDPV G C C AG
Sbjct: 498 HEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAG 557
Query: 557 WTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGH 616
W G RC +CP G WG NCS +C+C+NGG+C PE+G+C CAPGFRGP CQR C PG YG
Sbjct: 558 WMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGK 617
Query: 617 GCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS 676
C PC HS CH +G C CL G++G C+Q C G++G++CAQ C C + GTC
Sbjct: 618 RCV-PCKCANHSF--CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCH 674
Query: 677 PIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFC 736
P DGSC C GW G C + CP G +G C C C G C E GAC C PG +G C
Sbjct: 675 PQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPC 734
Score = 619 bits (1595), Expect = e-177
Identities = 291/723 (40%), Positives = 368/723 (50%), Gaps = 33/723 (4%)
Query: 163 CAAGF---RGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELC 219
C GF RG+ C LCA +C HG P +C C PG+ G C C
Sbjct: 90 CCHGFYESRGF-CVPLCAQ-----------ECVHGRCVAPN--QCQCVPGWRGDDCSSEC 135
Query: 220 PPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHH 279
PG G C+ C C N +C +G C+CP G C QPC PG +G C C CH
Sbjct: 136 APGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCH- 194
Query: 280 GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGY 339
G CD TG C C A G C C G+ GF C C NGG G+C C PG+
Sbjct: 195 GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGW 254
Query: 340 KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYY 399
G C CPEG HGP C+ C C N C TG C C PG++G C E CPVG +
Sbjct: 255 MGTICSLP-CPEGFHGPNCSQECRCH--NGGLCDRFTGQCRCAPGYTGDRCREECPVGRF 311
Query: 400 GDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS-CAAGTYGPNCSSICSCN--NGG 456
G C C C A C G C C GF G+ C C G YG +C + C+C+ +
Sbjct: 312 GQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSL 371
Query: 457 TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLG 516
+C P++G C+C GW GL C CP T G C E C C +G C G C C PG+ G
Sbjct: 372 SCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTG 431
Query: 517 DTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCS 576
C CP T+G+NCS C C +A C P+ G C C GW C CPPG WG +C+
Sbjct: 432 PHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCN 491
Query: 577 VSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHIS 636
SC C + CSP+ G+C C PG+ G CQ CP G +G GCA C C HS C +
Sbjct: 492 ASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCD-CDHSDG-CDPVH 549
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQA 696
G C+C G+ GA C+ C G +G +C+ C+C N GTC P +G+C C PG+ G C ++
Sbjct: 550 GRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRS 609
Query: 697 CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ 756
C PG +G C C C N + C +G C+C GWTG C+Q CP +G++C + CQC
Sbjct: 610 CQPGRYGKRCV-PCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCH 668
Query: 757 NGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPG 816
+G +C G C C G+TG HC + C GTFG C Q C+C C TG C C PG
Sbjct: 669 HGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPG 728
Query: 817 FKGIRCDQAALMMEELNPYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQ 876
G C + ++E P+T + P +S+GAV GI +L L+V L+ LF +R Q
Sbjct: 729 HSGAPC---RIGIQE--PFT-VMPTTPVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQ 782
Query: 877 KEK 879
K K
Sbjct: 783 KGK 785
Score = 417 bits (1072), Expect = e-116
Identities = 190/461 (41%), Positives = 236/461 (51%), Gaps = 22/461 (4%)
Query: 77 GLRTMYRRRSQCCPGYYESGDFCIPLCT-----EECVHGRCVSPDT--------CHCEPG 123
GL + + +C PGY +GD C C ++C +PD C CE G
Sbjct: 282 GLCDRFTGQCRCAPGY--TGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHG 339
Query: 124 WGGPDCSSG-CDSDHWGPHCSNRCQC--QNGALCNPITGACVCAAGFRGWRCEELCAPGT 180
+ G C+ C +G C C C ++ C+P+ G C C G+ G C E C T
Sbjct: 340 FTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDT 399
Query: 181 HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC 240
HG GCQ C C HG C +G C CAPGYTG +C LCPP ++G +C RC C+N C
Sbjct: 400 HGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIAC 459
Query: 241 HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDR 300
I GEC C GW C+ PCPPGT+G +C+ C C H C TG C CT G+ G
Sbjct: 460 SPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAH 519
Query: 301 CQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL 360
CQ CP G FG C+ CDC + C P G C+C+ G+ G RC CPEGL G C+
Sbjct: 520 CQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLS-CPEGLWGVNCSN 578
Query: 361 PCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
C C T C P G C C PG+ G C SC G YG C +PC C N + CH G
Sbjct: 579 TCTCKNGGT--CLPENGNCVCAPGFRGPSCQRSCQPGRYGKRC-VPCKCANHSFCHPSNG 635
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
C C G+ G C+ C G +G NC+ C C++GGTC P DGSC C GW G C C
Sbjct: 636 TCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGC 695
Query: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCEL 521
P GT+G NC++ C C G C P G+C C PG G C +
Sbjct: 696 PLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRI 736
Score = 267 bits (682), Expect = 4e-71
Identities = 120/285 (42%), Positives = 150/285 (52%), Gaps = 12/285 (4%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDT--CHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
C PG + G C C +C H SP T C C PGW G C C +G C++R
Sbjct: 481 CPPGTW--GFSCNASC--QCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASR 536
Query: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
C C + C+P+ G C C AG+ G RC C G G C C C++G +C P G C+
Sbjct: 537 CDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCV 596
Query: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265
CAPG+ G C+ C PG +G C + C C N CH G C C GWTG C+QPCPPG
Sbjct: 597 CAPGFRGPSCQRSCQPGRYGKRC-VPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPG 655
Query: 266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQ 325
+G+NC+Q C CHHGG C G C C G+ G C E CP G+FG CSQ C C G +
Sbjct: 656 HWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEK 715
Query: 326 CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTI 370
C P TGAC C PG+ G C+ G+ P +P A N++
Sbjct: 716 CHPETGACVCPPGHSGAPCR-----IGIQEPFTVMPTTPVAYNSL 755
Score = 68.6 bits (166), Expect = 3e-11
Identities = 50/128 (39%), Positives = 60/128 (46%), Gaps = 16/128 (12%)
Query: 922 KDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYVEMKSPVHMGSPYTDVPSL 981
K + E +S SL SSENPYATI+D P L ESSY+EMK P GSP P
Sbjct: 904 KGLISEEELGASVASL-SSENPYATIRDLPSLPGGPRESSYMEMKGPPS-GSPPRQPPQF 961
Query: 982 STSNKN----------IYEVEPTVSVVQEGCGHNSSYIQNA----YDLPRNSHIPGHYDL 1027
S + YE + ++ G YD P+NSHIPGHYDL
Sbjct: 962 WDSQRRRQPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDL 1021
Query: 1028 LPVRQSPA 1035
PVR P+
Sbjct: 1022 PPVRHPPS 1029
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 724 bits (1870), Expect = 0.0
Identities = 333/791 (42%), Positives = 401/791 (50%), Gaps = 60/791 (7%)
Query: 83 RRRSQCCPGYYESGDFCIPLCTE------ECVHGRCVSPDTCHCEPGWGGPDCSSGCDSD 136
R +++C GY+ G C CT + V G C C G+ G DC C
Sbjct: 681 RCQAECELGYFGPG--CWQACTCPVGVACDSVSGECGK----RCPAGFQGEDCGQECPVG 734
Query: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQ-CRHGA 195
+G +CS+ C C GA C+ +TG C C G G CE C G G GCQ C C+H A
Sbjct: 735 TFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAA 793
Query: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTG 255
CDP G CLC PG+ G C+++CP G +G C+ RC C N G CH TG C+C PGWTG
Sbjct: 794 RCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTG 853
Query: 256 AVCAQPCPPGTFGQNCSQDCPCHHG-GQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQC 314
C + C G +G +CS C C G G CD ++G C C AGY+G RC+++CP G FG C
Sbjct: 854 FSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGC 913
Query: 315 SQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHP 374
Q C C +G C +GAC C G++G C E CP G G C C C A +C
Sbjct: 914 EQRCQCQHGAACDHVSGACTCPAGWRGTFC-EHACPAGFFGLDCRSACNCTAG--AACDA 970
Query: 375 VTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCA 434
V G+C C G G C E+CP YG C C C NGA C + G C CAPG+MG C
Sbjct: 971 VNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCL 1030
Query: 435 VSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCT 494
+C AG YG NC C C NGGTC PV G C C EGW GL C C C S
Sbjct: 1031 QACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGG 1090
Query: 495 CANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCL 554
C NG C P G C C GW GD C+ PC G FG C++ C C C VTG C C
Sbjct: 1091 CLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCP 1150
Query: 555 AGWTGIRCDSTCPPGRWGPNCSVSCSCENGG-SCSPEDGSCECAPGFRGPLCQRICPPGF 613
G+TG C+ CPPG +G +C+ C C +C P G+C CA G+ GP CQ+ CPPG
Sbjct: 1151 PGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGR 1210
Query: 614 YGHGCAQPC------------------------------------PLCVH-----SSRPC 632
YG GC Q C P C H C
Sbjct: 1211 YGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAAC 1270
Query: 633 HHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKD 692
++G C C PG +G C + C FG C CSC N G C +GSC C GW G+
Sbjct: 1271 DPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRH 1330
Query: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV 752
C ACPPG +G AC CSCHN ++C G C C PG+ G C CP F G C +
Sbjct: 1331 CELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGL 1390
Query: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCY 812
C CQ+GA CD ISG+C C GF G CE+ C PG+FG GC Q C+C + CD VTG C
Sbjct: 1391 CWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCL 1450
Query: 813 CSPGFKGIRCD 823
C PG G C+
Sbjct: 1451 CPPGRSGATCN 1461
Score = 718 bits (1853), Expect = 0.0
Identities = 322/758 (42%), Positives = 398/758 (52%), Gaps = 32/758 (4%)
Query: 88 CCPGYYESGDFCI---------PLCTEECVHGRCVSPDT---------CHCEPGWGGPDC 129
C PG Y G FC P C+EEC +CV P T C C+ G+ G C
Sbjct: 628 CDPGLY--GRFCHLTCPPWAFGPGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERC 682
Query: 130 SSGCDSDHWGPHCSNRCQCQNGALCNPITGACV--CAAGFRGWRCEELCAPGTHGKGCQL 187
+ C+ ++GP C C C G C+ ++G C C AGF+G C + C GT G C
Sbjct: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSS 742
Query: 188 PCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP-CQNGGTCHHITGE 246
C C GA C G+C C PG TG CE CP G G C+ CP CQ+ C TG
Sbjct: 743 SCSCG-GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
Query: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECP 306
C C PG+ G+ C CP G +G +C C C + G C TG C C G+ G CQ C
Sbjct: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
Query: 307 FGSFGFQCSQHCDCHNG-GQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
G +G CS C+C G G C +G C CE GY GPRC+++ CP+G GPGC C C
Sbjct: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQCQ 920
Query: 366 ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCA 425
+ +C V+GACTC GW G C +CP G++G C+ C C GA C ++ G C C
Sbjct: 921 --HGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCP 978
Query: 426 PGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTW 485
G G CA +C A TYG NCS C+C NG +C PV G C C GW G C CP+G +
Sbjct: 979 AGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY 1038
Query: 486 GLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCD 545
G NC SC C NG C P+ G C+C GW G CE C C C + CD
Sbjct: 1039 GDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD 1098
Query: 546 PVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605
P TG C C AGWTG +C S C G +G C+ CSC G +C G+C C PGF G C
Sbjct: 1099 PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
Query: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
++ CPPG +G CAQ C C + CH +G C C G+ G C Q C G +G C Q
Sbjct: 1159 EQACPPGSFGEDCAQMCQ-CPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
Query: 666 LCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGAC 725
LC C N G+C G+C+C G++G DC+ CP G +GP C H C C GA+C G C
Sbjct: 1218 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTC 1277
Query: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAP 785
C PG G+ C + CP FG C C C+NG C +G C+C G+TG+HCE C P
Sbjct: 1278 LCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPP 1337
Query: 786 GTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCD 823
G +G C C C NNSTC+ TGTC C PGF G C+
Sbjct: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Score = 678 bits (1750), Expect = 0.0
Identities = 307/741 (41%), Positives = 376/741 (50%), Gaps = 55/741 (7%)
Query: 133 CDSDHWGPHCSNRCQ-CQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQC 191
C D +G CS C C+NG C C C G+ G C E C P T GK C C C
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 192 RHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP 251
++G +CD G C C PG +G CE+ CP G +G HC +C C N G CH + G C C P
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
Query: 252 GWTGAVCAQPCPPGTFGQNCSQDCPC--HHGGQCDHVTGQCHCTAGYMGDRCQ------- 302
G G C CPP FG CS++C C H CD G C C AG+ G+RCQ
Sbjct: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690
Query: 303 --------------------------------------EECPFGSFGFQCSQHCDCHNGG 324
+ECP G+FG CS C C G
Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGA 749
Query: 325 QCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPG 384
C TG C C PG G C E CPEG G GC CP + C P TGAC C PG
Sbjct: 750 PCHGVTGQCRCPPGRTGEDC-EADCPEGRWGLGCQEICPA-CQHAARCDPETGACLCLPG 807
Query: 385 WSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGP 444
+ G C + CP G+YG CQ C+C N CH TG C+CAPG+ G C +C G +GP
Sbjct: 808 FVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGP 867
Query: 445 NCSSICSCNNG-GTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSP 503
+CS C+C+ G G+C + G C C+ G+ G C CP G +G C + C C +GAAC
Sbjct: 868 DCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDH 927
Query: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCD 563
+ G+C+C GW G CE CP G FGL+C C+C+ CD V G C C AG G RC
Sbjct: 928 VSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCA 987
Query: 564 STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP 623
TCP +G NCS +C+C NG SC P G C CAPG+ GP C + CP G YG C C
Sbjct: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSC- 1046
Query: 624 LCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQ 683
LC + C +SG C C G++G C + C C C N G C P G C
Sbjct: 1047 LC-QNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCL 1105
Query: 684 CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAA 743
C GW G C C G++G AC CSC GA+C GAC C PG+TG C Q CP
Sbjct: 1106 CPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPG 1165
Query: 744 FFGKDCGRVCQCQ-NGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNS 802
FG+DC ++CQC +C +G C+C G+ G C+QRC PG +G GC+QLC C+N
Sbjct: 1166 SFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGG 1225
Query: 803 TCDHVTGTCYCSPGFKGIRCD 823
+CD TG C C GF G C+
Sbjct: 1226 SCDAATGACRCPTGFLGTDCN 1246
Score = 678 bits (1749), Expect = 0.0
Identities = 307/764 (40%), Positives = 382/764 (50%), Gaps = 23/764 (3%)
Query: 87 QCCPGYYESGDFCIPLCTE------------ECVHGRCVSPDT--CHCEPGWGGPDCSSG 132
+C PG +G+ C C E C H P+T C C PG+ G C
Sbjct: 759 RCPPG--RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 816
Query: 133 CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCR 192
C + +GP C RC C N C+P TG C CA G+ G+ C+ C G G C PC C
Sbjct: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCS 876
Query: 193 HG-ASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP 251
G SCD +G CLC GY G CE+ CP G G CE RC CQ+G C H++G C CP
Sbjct: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPA 936
Query: 252 GWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG 311
GW G C CP G FG +C C C G CD V G C C AG G RC E CP ++G
Sbjct: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
Query: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS 371
CSQ C C NG C P G C C PG+ GP C + CP GL+G C C C T
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQA-CPAGLYGDNCRHSCLCQNGGT-- 1053
Query: 372 CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGE 431
C PV+G C C GW+G C + C GC+ C NG C TG C C G+ G+
Sbjct: 1054 CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGD 1113
Query: 432 VCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNE 491
C C G +G C+ CSC G C V G+C C G+ G C CP G++G +C +
Sbjct: 1114 KCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQ 1173
Query: 492 SCTC-ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH 550
C C AC P G+CSC G+ G +C+ CP G +G C + C C + CD TG
Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
Query: 551 CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICP 610
C C G+ G C+ TCP GR+GPNC+ C C G +C P G+C C PG G C+R CP
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293
Query: 611 PGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCA 670
+G GC C + CH +G C C G++G C C G +G C CSC
Sbjct: 1294 QNRFGVGCEHTCSC--RNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
Query: 671 NNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPG 730
NN TC P G+C+C PG+ G+ C CPPGF G C C C +GA C G C C G
Sbjct: 1352 NNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
Query: 731 WTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY 790
+ G FC + C FG+ C + C C GA CD ++G C C G +G C C G FG
Sbjct: 1412 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Query: 791 GCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNP 834
C C+C + CD V+G C+C G+ G C + + NP
Sbjct: 1472 SCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENP 1515
Score = 629 bits (1623), Expect = e-180
Identities = 308/792 (38%), Positives = 378/792 (47%), Gaps = 90/792 (11%)
Query: 120 CEPGWGGPDCSSGCDSDHWGPHCS-----------------NRCQ----CQNGALCNPIT 158
CE GG CS GC GP C+ + C CQ NP
Sbjct: 335 CEANNGG--CSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGG 392
Query: 159 GACVCAAGFR----GWRCEELCAPGTHGKGCQLPCQCRHGA-SCDPRAGECL------CA 207
C C AG+R G CE++ + GC+ C G+ C AG L C+
Sbjct: 393 YECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCS 452
Query: 208 P------------------GYTGVYCEEL-----------------------------CP 220
P + V +EL C
Sbjct: 453 PLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCL 512
Query: 221 PGSHGAHCELRCP-CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHH 279
S G C L C C+NGGTC C CP GWTG +C + CPP TFG+NCS C C +
Sbjct: 513 DDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQN 572
Query: 280 GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGY 339
GG CD VTG C C G G C++ CP G +G C + C+C N G+C GAC C+PG
Sbjct: 573 GGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGL 632
Query: 340 KGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYY 399
G C CP GPGC+ C C +T SC G+C+C+ G+ G C C +GY+
Sbjct: 633 YGRFCH-LTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYF 691
Query: 400 GDGCQLPCTCQNGADCHSITGGC--TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGT 457
G GC CTC G C S++G C C GF GE C C GT+G NCSS CSC G
Sbjct: 692 GPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG-GAP 750
Query: 458 CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC-TCANGAACSPIDGSCSCTPGWLG 516
C V G C C G G DC CP G WGL C E C C + A C P G+C C PG++G
Sbjct: 751 CHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVG 810
Query: 517 DTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCS 576
C+ CP G +G +C C C++ C P TGHC C GWTG C C G WGP+CS
Sbjct: 811 SRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCS 870
Query: 577 VSCSCENG-GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHI 635
C+C G GSC G C C G+ GP C++ CP G +G GC Q C C H + C H+
Sbjct: 871 HPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQ-CQHGAA-CDHV 928
Query: 636 SGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQ 695
SG C C G+ G C C G+FG DC C+C C ++GSC C G G C++
Sbjct: 929 SGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAE 988
Query: 696 ACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQC 755
CP +G C AC+C NGASC G CHC PGW G C Q CPA +G +C C C
Sbjct: 989 TCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLC 1048
Query: 756 QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSP 815
QNG +CD +SG C C G+ G CE+ C P GC+ C+N CD TG C C
Sbjct: 1049 QNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPA 1108
Query: 816 GFKGIRCDQAAL 827
G+ G +C L
Sbjct: 1109 GWTGDKCQSPCL 1120
Score = 605 bits (1560), Expect = e-173
Identities = 261/618 (42%), Positives = 324/618 (52%), Gaps = 10/618 (1%)
Query: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVS--PDTCHCEPGWGGPDCSSGCDSDHWGP 140
R QC G++ G C C +C HG C C GW G C C + +G
Sbjct: 899 RCEQQCPQGHFGPG--CEQRC--QCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
Query: 141 HCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPR 200
C + C C GA C+ + G+C+C AG RG RC E C T+G C C C +GASCDP
Sbjct: 955 DCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPV 1014
Query: 201 AGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQ 260
G+C CAPG+ G C + CP G +G +C C CQNGGTC ++G CACP GW G C +
Sbjct: 1015 HGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEK 1074
Query: 261 PCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDC 320
C P C C +GG CD TG+C C AG+ GD+CQ C G FG C+Q C C
Sbjct: 1075 ECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSC 1134
Query: 321 HNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACT 380
G C TGAC C PG+ G C E+ CP G G C C C +N +CHP TG C+
Sbjct: 1135 PPGAACHHVTGACRCPPGFTGSGC-EQACPPGSFGEDCAQMCQCPGENP-ACHPATGTCS 1192
Query: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
C G+ G C + CP G YG GC+ C C NG C + TG C C GF+G C ++C G
Sbjct: 1193 CAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQG 1252
Query: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500
+GPNC+ +C C G C PV G+C C G G+ C CP +G+ C +C+C NG
Sbjct: 1253 RFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGL 1312
Query: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
C +GSCSC GW G CEL CP G +G C C C + C+P TG C C G+ G
Sbjct: 1313 CHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQ 1372
Query: 561 RCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQ 620
C+ CPPG G C C C++G C P G C C GF G C+R C PG +G GC Q
Sbjct: 1373 ACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQ 1432
Query: 621 PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG 680
C PC ++G+C C PG SGA CN C G FG C C C C P+ G
Sbjct: 1433 RCD--CDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGPSCTLHCDCGGGADCDPVSG 1490
Query: 681 SCQCFPGWIGKDCSQACP 698
C C G++G C + P
Sbjct: 1491 QCHCVDGYMGPTCREGGP 1508
Score = 482 bits (1240), Expect = e-136
Identities = 311/988 (31%), Positives = 383/988 (38%), Gaps = 222/988 (22%)
Query: 18 LALNPEDPNVCSHWESYAVTVQESYAHPFDQ---IYYTRCTDILNWFK-CTRH--RISYK 71
L L P P+VC+ E V ++ ++ C W C H R Y
Sbjct: 38 LPLQPGMPHVCAEQELTLVGRRQPCVQALSHTVPVWKAGC----GWQAWCVGHERRTVYY 93
Query: 72 TAYRRGLRTMYRRRSQCCPGYY----ESGDFCIPLCTEECVHG-RCV--SPDTCHCEPGW 124
YR+ T R +CC G+ E G C HG RCV S CHC PG+
Sbjct: 94 MGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGF 153
Query: 125 GGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR----GWRCEELCAPGT 180
GP C D D H CQ+ + P + C C GFR C + +
Sbjct: 154 QGPRCQ--YDVDECRTHNGG---CQHRCVNTPGSYLCECKPGFRLHTDSRTCLAINSCAL 208
Query: 181 HGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQN-GGT 239
GCQ H C C PG+ G HC R PC N G+
Sbjct: 209 GNGGCQ-----HHCVQLTITRHRCQCRPGF---------QLQEDGRHCVRRSPCANRNGS 254
Query: 240 CHH----ITG--ECACPPGW----TGAVCAQ---------PCPPGTFGQNCSQDCPCHHG 280
C H + G C C G+ G C C G S C CH G
Sbjct: 255 CMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAG 314
Query: 281 -------------------------GQCDHVTGQ------CHCTAGYMGDR--------- 300
G C H C C GY D
Sbjct: 315 YELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVD 374
Query: 301 -------CQEECPFGSFGFQC---------SQHCDCHNGGQCSPTTGACE---------- 334
CQ+ C G++C + C C + +C+ + G CE
Sbjct: 375 DCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECASSRGGCEHHCTNLAGSF 434
Query: 335 ---CEPGYKGPRCQERLCPEGLHGPGCTL--------PCPCDA-----------DNTISC 372
CE GY+ + P L P L P P A D+ +
Sbjct: 435 QCSCEAGYRLHEDRRGCSP--LEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGA 492
Query: 373 ----------HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGC 422
H +T C GH C+ +C C+NG C GC
Sbjct: 493 DEEEAELRGEHTLTEKFVCLDDSFGHDCSLTCD------------DCRNGGTCLLGLDGC 540
Query: 423 TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPS 482
C G+ G +C +C T+G NCS CSC NGGTC V G+C C G G +C CP
Sbjct: 541 DCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGACRCPPGVSGTNCEDGCPK 600
Query: 483 GTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC--SH 540
G +G +C + C CAN C + G+C C PG G C L CP FG CSE C C H
Sbjct: 601 GYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPH 660
Query: 541 ADGCDPVTGHCCCLAGWTGIRCDS------------------------------------ 564
CD G C C AG+ G RC +
Sbjct: 661 TQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPA 720
Query: 565 ---------TCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYG 615
CP G +G NCS SCSC G C G C C PG G C+ CP G +G
Sbjct: 721 GFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWG 779
Query: 616 HGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTC 675
GC + CP C H++R C +G C CLPGF G+ C VC G++G C CSCAN+G C
Sbjct: 780 LGCQEICPACQHAAR-CDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHC 838
Query: 676 SPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNG-ASCSAEDGACHCTPGWTGL 734
P G C C PGW G C +AC G WGP C H C+C G SC A G C C G+ G
Sbjct: 839 HPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGP 898
Query: 735 FCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ 794
C Q+CP FG C + CQCQ+GA+CDH+SG CTC G+ G CE C G FG C+
Sbjct: 899 RCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRS 958
Query: 795 LCECMNNSTCDHVTGTCYCSPGFKGIRC 822
C C + CD V G+C C G +G RC
Sbjct: 959 ACNCTAGAACDAVNGSCLCPAGRRGPRC 986
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 316 bits (809), Expect = 8e-86
Identities = 285/971 (29%), Positives = 360/971 (37%), Gaps = 296/971 (30%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCH---------CEPGWGGPDCSSGCDS--D 136
C PG+ G C + + CV +C + TC C W G DCS D
Sbjct: 264 CPPGFI--GPDC-EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET 320
Query: 137 HWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE---------------------- 174
PHC N CQN A + CVC +G+ G CEE
Sbjct: 321 QGPPHCRNGGTCQNSAG----SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGS 376
Query: 175 ---LCAPGTHGKGCQL-------PCQCRHGASCDPRAGE--CLCAPGYTGVYCEE---LC 219
LC PG G C L PC S +P G CLC PGY+G C + C
Sbjct: 377 FSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
Query: 220 PPGSHGAHCELRCPCQNGGTCHHITGE--CACPPGWTGAVC--------AQPC------- 262
G PC++GG+C + G C CPPG+TG+ C +QPC
Sbjct: 437 LMAQQGPS-----PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL 491
Query: 263 ----------PPGTFGQNC---SQDC---PCHHGGQC-DHVTG-QCHCTAGYMGDRCQEE 304
PPG GQ C + +C PC + C D + G QC C G+ G RC+E+
Sbjct: 492 DLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEED 551
Query: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQER--------------- 347
+C + C NGGQC GA C+C PG++GPRCQ
Sbjct: 552 ID------EC-RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASC 604
Query: 348 ---------LCPEGLHGPGCTLP---------------------CPCDADNTISCHPVTG 377
LCP G G C +P C C D + C P
Sbjct: 605 LDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP-DGSPGCAPPED 663
Query: 378 ACTCQPGWSGHHCNES---CPVGYYGDGCQ------LPCTCQNGADCHSITGG--CTCAP 426
CTC G HC S C VG+ G C+ + C +G C+ G CTC
Sbjct: 664 NCTCHHG----HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPT 719
Query: 427 GFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDC-------- 476
G+ G C+ A GP C NGG+C+P G CTC G C
Sbjct: 720 GYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCV 772
Query: 477 TLPCPSGTWGLNC--NESCTCANGAACSPIDG----SCSCTPGWLGDTCE-------LPC 523
+ PC +G +N SC CA G +G SC+ +P TC+ C
Sbjct: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLC 832
Query: 524 PDGTFGLNCSEHCDCSHADGCDP-----VTG---HCCCLAGWTGIRCD---STCPPGRWG 572
P G G +C D C TG HC CL GWTG C+ S+C
Sbjct: 833 PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALS 892
Query: 573 PNCSVSCSCENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSR 630
VS C NGG C S C C PGF+G LCQ PC SR
Sbjct: 893 QGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ----------DHVNPC-----ESR 937
Query: 631 PCHHISGICECLPGFSGALCNQVCAGGYFGQDCA------QLCSCANNGTCSPIDGS--C 682
PC + + C+ SG LC CA GY GQ+C+ Q C N+GTC+P G C
Sbjct: 938 PCQNGA---TCMAQPSGYLCQ--CAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC 992
Query: 683 QCFPGWIGKDCSQ---------------------------ACPPGFWGPAC------FHA 709
C PG++G C C PG G C H+
Sbjct: 993 ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHS 1052
Query: 710 CSCHNGASCSAEDGA-----CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC--- 761
C +G +C A G+ CHC G+ G C+ R P+ F C +G C
Sbjct: 1053 QPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH-------HCHHGGLCLPS 1105
Query: 762 --DHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG------TCYC 813
+C C +G+ G C AP GC C+ N +C TG C C
Sbjct: 1106 PKPGFPPRCACLSGYGGPDCLTPPAPK----GCGPPSPCLYNGSCSETTGLGGPGFRCSC 1161
Query: 814 SPGFKGIRCDQ 824
G RC +
Sbjct: 1162 PHSSPGPRCQK 1172
Score = 296 bits (757), Expect = 9e-80
Identities = 275/963 (28%), Positives = 334/963 (34%), Gaps = 290/963 (30%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQ 147
C PG+ +G+ C + C C CH + G P CS C G C R
Sbjct: 105 CLPGF--TGERCQAKLEDPCPPSFCSKRGRCHIQAS-GRPQCS--CMPGWTGEQCQLRDF 159
Query: 148 CQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC--------QLPCQCRHGASCDP 199
C NP VC A + +C C PG G C Q P C G SC
Sbjct: 160 CS----ANPCVNGGVCLATYPQIQCH--CPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
Query: 200 RAG--ECLCAPGYTGVYCEE-----------------------------LCPPGSHGAHC 228
G +CLC G G CE LCPPG G C
Sbjct: 214 TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC 273
Query: 229 ELR---C---PCQNGGTCHH--ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCP--CH 278
E+ C CQNGGTC T C CP WTG C++ C P C
Sbjct: 274 EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV------DECETQGPPHCR 327
Query: 279 HGGQCDHVTGQCHCT--AGYMGDRCQEE-------------------------CPFGSFG 311
+GG C + G HC +G+ G C+E CP G G
Sbjct: 328 NGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTG 387
Query: 312 FQC--SQHC---DCHNGGQCS--PTTGA--CECEPGYKGPRCQERL--CPEGLHGPGCTL 360
C C CH QCS P TG+ C C+PGY GP C + L C GP
Sbjct: 388 LLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS--- 444
Query: 361 PCPCDADNTISCHPVTGACTCQPGWSGHHCNES-------------------------CP 395
PC+ + P + C C PG++G C CP
Sbjct: 445 --PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
Query: 396 VGYYGDGCQLPCT------CQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCS 447
G G C++ C N ADCH + G C C PGF G C P
Sbjct: 503 PGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--- 559
Query: 448 SICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID 505
C NGG C G+ C C G++G C S C GA+C +
Sbjct: 560 ----CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL-------SDPCPVGASCLDLP 608
Query: 506 GS--CSCTPGWLGDTCELP-----------------------CPDGTFGLNCSE-HCDCS 539
G+ C C G+ G CE+P CPDG+ G E +C C
Sbjct: 609 GAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCH 668
Query: 540 HADGCDPVTGHCCCLAGWTGIRCDS-------------------------TCPPGRWGPN 574
H C C C GWTG C++ TCP G GP
Sbjct: 669 HGH-CQ--RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPT 725
Query: 575 CSVSCS------CENGGSCSPEDGS--CECAPGFRGPLCQR------------------- 607
CS + C NGGSC+P G C C P GP CQ
Sbjct: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
Query: 608 ------ICPPGFYGHGCAQPC-PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG 660
+C GF G C P C S PC + C+ P G C +C GY G
Sbjct: 786 PGTFSCLCAMGFQGPRCEGKLRPSCADS--PCRN-RATCQDSP--QGPRC--LCPTGYTG 838
Query: 661 QDCA---QLCS---CANNGTCSPIDGS--CQCFPGWIGKDCS---QACPPGFWGPACFHA 709
C LC+ C N C S C C GW G C+ +C +
Sbjct: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVS 898
Query: 710 CSCHNGASC--SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQNGASC-DH 763
CHNG C S CHC PG+ G C +D C+ CQNGA+C
Sbjct: 899 SLCHNGGLCVDSGPSYFCHCPPGFQGSLC----------QDHVNPCESRPCQNGATCMAQ 948
Query: 764 ISGK-CTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGT--CYCSPGFKGI 820
SG C C G+ GQ+C + CQ C N+ TC G C C PGF G+
Sbjct: 949 PSGYLCQCAPGYDGQNCSKELD------ACQSQ-PCHNHGTCTPKPGGFHCACPPGFVGL 1001
Query: 821 RCD 823
RC+
Sbjct: 1002 RCE 1004
Score = 260 bits (664), Expect = 5e-69
Identities = 253/893 (28%), Positives = 322/893 (36%), Gaps = 259/893 (29%)
Query: 105 EECVHG-RCVS----PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC----- 154
E C +G C+S TC C PG+ G C + C N CQNG C
Sbjct: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQ-------FPDPCQNAQLCQNGGSCQALLP 85
Query: 155 ---------NPITGA--CVCAAGFRGWRC----EELCAPGTHGKGCQLPCQCRHGASCDP 199
+P+T + C C GF G RC E+ C P C +C AS P
Sbjct: 86 APLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----CSKRGRCHIQASGRP 141
Query: 200 RAGECLCAPGYTGVYCEEL------------------------CPPGSHGAHCEL---RC 232
+C C PG+TG C+ CPPG G CE C
Sbjct: 142 ---QCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNEC 198
Query: 233 -----PCQNGGTCHHITG--ECACPPGWTGAVC---AQPCPPGTFGQNCSQDCPCHHGGQ 282
PC G +CH+ G +C CP G G C A PCPP + CS C +
Sbjct: 199 FQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP----RGCSNGGTCQLMPE 254
Query: 283 CDHVTGQCHCTAGYMGDRCQEE-------------------------CPFGSFGFQCSQH 317
D C C G++G C+ CP G+ CS+
Sbjct: 255 KDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED 314
Query: 318 CD---------CHNGGQCSPTTGA--CECEPGYKGPRCQERL--CPEGLHGPGCTLPCPC 364
D C NGG C + G+ C C G+ G C+E L C PG T
Sbjct: 315 VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC---I 371
Query: 365 DADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHS--ITGG- 421
D + SC C PG +G C + D C L C A C + +TG
Sbjct: 372 DRVGSFSC-------LCPPGRTGLLC-------HLEDMC-LSQPCHGDAQCSTNPLTGST 416
Query: 422 -CTCAPGFMGEVCAVS---CAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCT 477
C C PG+ G C C GP+ C +GG+C GS C
Sbjct: 417 LCLCQPGYSGPTCHQDLDECLMAQQGPS-----PCEHGGSCLNTPGSFNCL--------- 462
Query: 478 LPCPSGTWGLNC----NE--SCTCANGAACSPIDGS--CSCTPGWLGDTCELPCPDGTFG 529
CP G G C NE S C G+ C + + C C PG G CE+ +
Sbjct: 463 --CPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE---- 516
Query: 530 LNCSEHCDCSHADGCDPVTG-HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCS 588
C+ +HAD D + G C CL G++G RC+ R P C NGG C
Sbjct: 517 --CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------CANGGQCQ 567
Query: 589 PEDGS--CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISG--ICECLPG 644
+ G+ C+C PGF GP CQ + PCP+ C + G C C G
Sbjct: 568 DQPGAFHCKCLPGFEGPRCQTEVDECL-----SDPCPV----GASCLDLPGAFFCLCPSG 618
Query: 645 FSGALCN------------QVCAGGYFGQDCAQLCSCANNGTCSPIDG-----------S 681
F+G LC Q+C +C LC + G P D S
Sbjct: 619 FTGQLCEVPLCAPNLCQPKQICKDQKDKANC--LCPDGSPGCAPPEDNCTCHHGHCQRSS 676
Query: 682 CQCFPGWIGKDCSQAC-----PPGFWGPACF-----HACSC---HNGASCSAEDGACH-- 726
C C GW G +C P G C+ + C+C + G +CS E ACH
Sbjct: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
Query: 727 -------CTPGWTGLFCTQRCPAAFFGKDCGRVCQ------CQNGASCDHISG--KCTCR 771
C P G +CT CP + G C C NG +C + G C C
Sbjct: 737 PCLNGGSCNPSPGGYYCT--CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA 794
Query: 772 TGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTC-DHVTG-TCYCSPGFKGIRC 822
GF G CE + P C C N +TC D G C C G+ G C
Sbjct: 795 MGFQGPRCEGKLRP-----SCAD-SPCRNRATCQDSPQGPRCLCPTGYTGGSC 841
Score = 214 bits (546), Expect = 3e-55
Identities = 230/837 (27%), Positives = 276/837 (32%), Gaps = 260/837 (31%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCH---------CEPGWGGPDCSSGCDSDHW 138
C PG G C + T EC C++ CH C PG+ G C D
Sbjct: 501 CPPGL--EGQLC-EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557
Query: 139 GPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCD 198
P C+N QCQ+ P C C GF G RC+ T C L C GASC
Sbjct: 558 SP-CANGGQCQD----QPGAFHCKCLPGFEGPRCQ------TEVDEC-LSDPCPVGASCL 605
Query: 199 --PRAGECLCAPGYTGVYCEE-----------------------LCPPGSHGAHCELRCP 233
P A CLC G+TG CE LCP GS G P
Sbjct: 606 DLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGC-----AP 660
Query: 234 CQNGGTCHH---ITGECACPPGWTGAVCA-------------------QP------CPPG 265
++ TCHH C C GWTG C QP CP G
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 266 TFGQNCSQDC------PCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD 319
G CS++ PC +GG C+ G +CT CP G QC D
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCT-----------CPPSHTGPQCQTSTD 769
Query: 320 ------CHNGGQC--SPTTGACECEPGYKGPRCQERL--------------CPEGLHGPG 357
C NGG C P T +C C G++GPRC+ +L C + GP
Sbjct: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR 829
Query: 358 CTLPC-----------------PCDADNTISCHPVTGACTCQPGWSGHHCN---ESCPVG 397
C P PC ++ + C C GW+G CN SC
Sbjct: 830 CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKA 889
Query: 398 YYGDGCQLPCTCQNGADCHSITGG----CTCAPGFMGEVCA------------------- 434
G + C NG C + G C C PGF G +C
Sbjct: 890 ALSQGIDVSSLCHNGGLC--VDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMA 947
Query: 435 ------VSCAAGTYGPNCSS---ICS---CNNGGTCSPVDGS--CTCKEGWQGLDCT--- 477
CA G G NCS C C+N GTC+P G C C G+ GL C
Sbjct: 948 QPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDV 1007
Query: 478 -----LPC-PSGTWGLNCNES---CTCANGAA---CSPIDGSCSCTPGWLGDTCELP--- 522
PC P+GT + + C C G C C P + G TCE
Sbjct: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGS 1067
Query: 523 -------CPDGTFGLNCSEHCD------CSHADGCDP-----VTGHCCCLAGWTGIRCDS 564
CP G G CS C H C P C CL+G+ G C
Sbjct: 1068 PLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDC-- 1125
Query: 565 TCPPGRWGPNCSVSCSCENGGSCSPEDG------SCECAPGFRGPLCQRICPPGFYGH-- 616
PP G C C GSCS G C C GP CQ+ G G
Sbjct: 1126 LTPPAPKG--CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSG 1183
Query: 617 ------GCAQP--------CPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGG---YF 659
GC+ P C L V P C F C+ C +
Sbjct: 1184 DGACDAGCSGPGGNWDGGDCSLGVPD--PWKGCPSHSRCWLLFRDGQCHPQCDSEECLFD 1241
Query: 660 GQDCAQLCSCA-----------NNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPA 705
G DC +C +NG C + +C GW G DC WGP+
Sbjct: 1242 GYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAEC--GWDGGDCRPEDGDPEWGPS 1296
Score = 169 bits (428), Expect = 1e-41
Identities = 161/558 (28%), Positives = 201/558 (36%), Gaps = 178/558 (31%)
Query: 406 PCTCQNGADCHSIT---GGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC---- 458
P C NG C S++ G C CAPGF+GE C + C + C NGG+C
Sbjct: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETC-------QFPDPCQNAQLCQNGGSCQALL 84
Query: 459 ----------SPVDGS--CTCKEGWQGLDCTL----PCPSGTWGLNCNESCTCANGAACS 502
SP+ S CTC G+ G C PCP C++ C A+
Sbjct: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----CSKRGRCHIQASGR 140
Query: 503 PIDGSCSCTPGWLGDTCEL-------PCPDGTFGLNCSEHCDCSHADGCDPVTGHCC--- 552
P CSC PGW G+ C+L PC +G L C G + GH C
Sbjct: 141 P---QCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE---GHACERD 194
Query: 553 ---CLAG----WTGIRCDST-------CPPGRWGPNCSVSC------SCENGGSCS--PE 590
C G C +T CP G+ GP C + C NGG+C PE
Sbjct: 195 VNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
Query: 591 DGS----CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFS 646
S C C PGF GP C+ + P H C G C+ G
Sbjct: 255 KDSTFHLCLCPPGFIGPDCE-VNPDNCVSHQCQN---------------GGTCQ--DGLD 296
Query: 647 GALCNQVCAGGYFGQDCAQLCS---------CANNGTCSPIDGS--CQCFPGWIGKDCSQ 695
C +C + G DC++ C N GTC GS C C GW G C +
Sbjct: 297 TYTC--LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
Query: 696 -------------------------ACPPGFWGPACF--HAC---SCHNGASCSAE---- 721
CPPG G C C CH A CS
Sbjct: 355 NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTG 414
Query: 722 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHC 779
C C PG++G C Q + C++G SC + G C C G+TG C
Sbjct: 415 STLCLCQPGYSGPTCHQDLDECLMAQQ--GPSPCEHGGSCLNTPGSFNCLCPPGYTGSRC 472
Query: 780 E--------QRCAPG--------TFGYGCQ-----QLCE----------CMNNSTC-DHV 807
E Q C PG TF C QLCE C+N++ C D +
Sbjct: 473 EADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLL 532
Query: 808 TG-TCYCSPGFKGIRCDQ 824
G C C PGF G RC++
Sbjct: 533 NGFQCICLPGFSGTRCEE 550
Score = 135 bits (340), Expect = 2e-31
Identities = 122/441 (27%), Positives = 159/441 (36%), Gaps = 132/441 (29%)
Query: 495 CANGAACSPID---GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGC------- 544
CANG C + G+C C PG+LG+TC+ P P C C + C
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-------CQNAQLCQNGGSCQALLPAP 87
Query: 545 -------DPVTGH--CCCLAGWTGIRC----DSTCPPGRWGPNCSVSCSCENGGSCSPED 591
P+T C CL G+TG RC + CPP CS C S P+
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPS----FCSKRGRCHIQASGRPQ- 142
Query: 592 GSCECAPGFRGPLCQR------------------------ICPPGFYGHGCAQPCPLCVH 627
C C PG+ G CQ CPPGF GH C + C
Sbjct: 143 --CSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQ 200
Query: 628 SSRP------CHHISGICECLPGFSGALCNQVCAGGYFGQDC---AQLC---SCANNGTC 675
P CH+ G +CL C G G C A C C+N GTC
Sbjct: 201 DPGPCPKGTSCHNTLGSFQCL-----------CPVGQEGPRCELRAGPCPPRGCSNGGTC 249
Query: 676 SPIDGS------CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDG----AC 725
+ C C PG+IG DC P + C NG +C +DG C
Sbjct: 250 QLMPEKDSTFHLCLCPPGFIGPDCEV-------NPDNCVSHQCQNGGTC--QDGLDTYTC 300
Query: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK--CTCRTGFTGQHCEQR- 782
C WTG C++ + C+NG +C + +G C C +G+ G CE+
Sbjct: 301 LCPETWTGWDCSEDVDEC----ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
Query: 783 --CAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCDQAALMMEELNPYTKI 838
C T C STC G +C C PG G+ C + + +
Sbjct: 357 DDCIAAT----------CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ------- 399
Query: 839 SPALGAERHSVGAVTGIMLLL 859
P G + S +TG L L
Sbjct: 400 -PCHGDAQCSTNPLTGSTLCL 419
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 294 bits (752), Expect = 3e-79
Identities = 151/384 (39%), Positives = 187/384 (48%), Gaps = 49/384 (12%)
Query: 87 QCCPGYYESGDFC-IPLCT--EECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
QCC G+ + C IP+C + C CV P C C+PG+ G CSS C +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGK-----------------GC 185
C C C P TGAC C A G RCE CA G HG+ C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 186 QLPCQCRHGAS-CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL---RCPCQNG---- 237
+ PCQC A+ C+ G C+C PG+ G C C HG+ CE RC C+ G
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGP 217
Query: 238 ----------GTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-PCHHGGQCDHV 286
G C +GEC CPPG+ GA C PCP G+ G C+ C C H C
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 287 TGQCH-CTAGYMGDRCQEECPFGSFGFQCSQHC-DCHNGGQCSPTTGACE-CEPGYKGPR 343
TG C C G+ G +CQ+ C G+FG C Q C C +G C P TG C+ C+PG+ GPR
Sbjct: 278 TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPR 337
Query: 344 CQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC 403
C++ CP G G C CP SC VTG C C G+ G CN SCP G++G+ C
Sbjct: 338 CEDP-CPTGTFGEDCGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNC 394
Query: 404 QLPCTCQNGADCHSITGGCTCAPG 427
+PC C G CH ++G C G
Sbjct: 395 SVPCECPEGL-CHPVSGSCQPGSG 417
Score = 286 bits (733), Expect = 5e-77
Identities = 161/429 (37%), Positives = 193/429 (44%), Gaps = 64/429 (14%)
Query: 212 GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT--GAVCAQPCPPGTFGQ 269
G EL P G H C P + E C GW C P G
Sbjct: 16 GTQGSELDPKGQHV--CVASSP----------SAELQCCAGWRQKDQECTIPICEGP--D 61
Query: 270 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
C +D C G C C G+ G C CP +G C + C CH GQC P
Sbjct: 62 ACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPA 114
Query: 330 TGACECEPGYKGPRCQERLCPEGLHG------------PG-----CTLPCPCDADNTISC 372
TGAC+C+ G RC E C G HG PG C PC C+ C
Sbjct: 115 TGACQCQADRWGARC-EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA-AARC 172
Query: 373 HPVTGACTCQPGWSGHHCNE----------------SCPVGYYGDGCQLPCTCQNGADCH 416
TGAC C+PGW G C+ +C G++G CQ C C G C
Sbjct: 173 EQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CS 231
Query: 417 SITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS-CNNGGTCSPVDGSC-TCKEGWQGL 474
+ +G CTC PGF G C + C AG++G C+ C C + CSP GSC +C+ GW G
Sbjct: 232 AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGT 291
Query: 475 DCTLPCPSGTWGLNCNESCT-CANGAACSPIDGSCS-CTPGWLGDTCELPCPDGTFGLNC 532
C PC GT+G +C + C C +G AC P G C C PGWLG CE PCP GTFG +C
Sbjct: 292 QCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDC 351
Query: 533 SEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG 592
C CD VTG C C AG+ G C+++CP G G NCSV C C G C P G
Sbjct: 352 GSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE-GLCHPVSG 410
Query: 593 SCECAPGFR 601
SC+ G R
Sbjct: 411 SCQPGSGSR 419
Score = 281 bits (720), Expect = 2e-75
Identities = 145/412 (35%), Positives = 172/412 (41%), Gaps = 54/412 (13%)
Query: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
C GW + P+ C+ P CQ C G C C PGF G C+ C
Sbjct: 41 CCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQ 93
Query: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500
+GP+C C C+ G C P G+C C+ + WG C C C
Sbjct: 94 YWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWGARCEFPCACGPHGR 140
Query: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
C P G C C PGW TC PC T C + TG C C GW G
Sbjct: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGWWGR 188
Query: 561 RCD----------------STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPL 604
RC C PG WGP C C C G CS G C C PGFRG
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGFRGAR 247
Query: 605 CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE-CLPGFSGALCNQVCAGGYFGQDC 663
C+ CP G +G CA C C H + PC +G CE C PG++G C Q C G FG+ C
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKH-NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESC 306
Query: 664 AQLC-SCANNGTCSPIDGSCQ-CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAE 721
Q C C + C P G CQ C PGW+G C CP G +G C C SC
Sbjct: 307 EQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTV 366
Query: 722 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTG 773
G C C+ G+ G C CPA F G +C C+C G C +SG C +G
Sbjct: 367 TGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSG 417
Score = 271 bits (692), Expect = 3e-72
Identities = 144/395 (36%), Positives = 168/395 (42%), Gaps = 54/395 (13%)
Query: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSP 503
P C +C C G C CK G+ G C+ CP WG +C ESC C C P
Sbjct: 55 PICEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
Query: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGW------ 557
G+C C G CE PC G G CDP TG C C GW
Sbjct: 114 ATGACQCQADRWGARCEFPCACGPHGR-------------CDPATGVCHCEPGWWSSTCR 160
Query: 558 -------TGIRCDST-----CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605
RC+ C PG WG CS C+C +G C + G C C PG+ GP C
Sbjct: 161 RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPEC 219
Query: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
Q+ C CV C SG C C PGF GA C C G G CA
Sbjct: 220 QQQCE--------------CVRGR--CSAASGECTCPPGFRGARCELPCPAGSHGVQCAH 263
Query: 666 LCS-CANNGTCSPIDGSCQ-CFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAED 722
C C +N CSP GSC+ C PGW G C Q C PG +G +C C C +G +C +
Sbjct: 264 SCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDT 323
Query: 723 GACH-CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQ 781
G C C PGW G C CP FG+DCG C SCD ++G C C G+ G C
Sbjct: 324 GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNA 383
Query: 782 RCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPG 816
C G G C CEC C V+G+C G
Sbjct: 384 SCPAGFHGNNCSVPCEC-PEGLCHPVSGSCQPGSG 417
Score = 236 bits (602), Expect = 8e-62
Identities = 130/381 (34%), Positives = 163/381 (42%), Gaps = 63/381 (16%)
Query: 467 CKEGWQGLD--CTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCP 524
C GW+ D CT+P G +E C G C C PG+ G C CP
Sbjct: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKP---------GLCRCKPGFFGAHCSSRCP 91
Query: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584
+G +C E C C C+P TG C C A RWG C C+C
Sbjct: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCACGPH 138
Query: 585 GSCSPEDGSCECAPGFRGPLCQR------------------ICPPGFYGHGCAQPCPLCV 626
G C P G C C PG+ C+R +C PG++G C+ C
Sbjct: 139 GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-- 196
Query: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFP 686
H S PC SG C C PG ++G +C Q C C G CS G C C P
Sbjct: 197 HGS-PCEQDSGRCACRPG-------------WWGPECQQQCECVR-GRCSAASGECTCPP 241
Query: 687 GWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGACH-CTPGWTGLFCTQRCPAAF 744
G+ G C CP G G C H+C C + CS + G+C C PGW G C Q C
Sbjct: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301
Query: 745 FGKDCGRVC-QCQNGASCDHISGKCT-CRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNS 802
FG+ C + C C++G +C+ +G C C G+ G CE C GTFG C C
Sbjct: 302 FGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG 361
Query: 803 TCDHVTGTCYCSPGFKGIRCD 823
+CD VTG C CS G+ G C+
Sbjct: 362 SCDTVTGDCVCSAGYWGPSCN 382
Score = 159 bits (402), Expect = 1e-38
Identities = 83/227 (36%), Positives = 104/227 (45%), Gaps = 37/227 (16%)
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQC----------FP 686
G+C C PGF GA C+ C G Y+G DC + C C +G C P G+CQC FP
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 687 GWIGKD--CSQA-----CPPGFWGPACFHACSCHNGAS-CSAEDGACHCTPGWTGLFCTQ 738
G C A C PG+W C C C+ A+ C GAC C PGW G C+
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 739 RCPA----------------AFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQR 782
RC ++G +C + C+C G C SG+CTC GF G CE
Sbjct: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELP 251
Query: 783 CAPGTFGYGCQQLC-ECMNNSTCDHVTGTCY-CSPGFKGIRCDQAAL 827
C G+ G C C C +N C TG+C C PG+ G +C Q L
Sbjct: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCL 298
Score = 60.1 bits (144), Expect = 1e-08
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 11/125 (8%)
Query: 719 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQH 778
S+ C GW Q C C CQ C G C C+ GF G H
Sbjct: 33 SSPSAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAH 85
Query: 779 CEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKI 838
C RC +G C++ C C + C+ TG C C G RC+ P+ +
Sbjct: 86 CSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC----ACGPHGRC 141
Query: 839 SPALG 843
PA G
Sbjct: 142 DPATG 146
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 96 GDFCIPLCTEECVHGRC--VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGAL 153
G+ C C CV G C V+ D C C G+ GP C++ C + G +CS C+C G L
Sbjct: 348 GEDCGSTCPT-CVQGSCDTVTGD-CVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG-L 404
Query: 154 CNPITGACVCAAGFR 168
C+P++G+C +G R
Sbjct: 405 CHPVSGSCQPGSGSR 419
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 294 bits (752), Expect = 3e-79
Identities = 151/384 (39%), Positives = 187/384 (48%), Gaps = 49/384 (12%)
Query: 87 QCCPGYYESGDFC-IPLCT--EECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
QCC G+ + C IP+C + C CV P C C+PG+ G CSS C +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGK-----------------GC 185
C C C P TGAC C A G RCE CA G HG+ C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 186 QLPCQCRHGAS-CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL---RCPCQNG---- 237
+ PCQC A+ C+ G C+C PG+ G C C HG+ CE RC C+ G
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGP 217
Query: 238 ----------GTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-PCHHGGQCDHV 286
G C +GEC CPPG+ GA C PCP G+ G C+ C C H C
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 287 TGQCH-CTAGYMGDRCQEECPFGSFGFQCSQHC-DCHNGGQCSPTTGACE-CEPGYKGPR 343
TG C C G+ G +CQ+ C G+FG C Q C C +G C P TG C+ C+PG+ GPR
Sbjct: 278 TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPR 337
Query: 344 CQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC 403
C++ CP G G C CP SC VTG C C G+ G CN SCP G++G+ C
Sbjct: 338 CEDP-CPTGTFGEDCGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNC 394
Query: 404 QLPCTCQNGADCHSITGGCTCAPG 427
+PC C G CH ++G C G
Sbjct: 395 SVPCECPEGL-CHPVSGSCQPGSG 417
Score = 286 bits (733), Expect = 5e-77
Identities = 161/429 (37%), Positives = 193/429 (44%), Gaps = 64/429 (14%)
Query: 212 GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT--GAVCAQPCPPGTFGQ 269
G EL P G H C P + E C GW C P G
Sbjct: 16 GTQGSELDPKGQHV--CVASSP----------SAELQCCAGWRQKDQECTIPICEGP--D 61
Query: 270 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
C +D C G C C G+ G C CP +G C + C CH GQC P
Sbjct: 62 ACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPA 114
Query: 330 TGACECEPGYKGPRCQERLCPEGLHG------------PG-----CTLPCPCDADNTISC 372
TGAC+C+ G RC E C G HG PG C PC C+ C
Sbjct: 115 TGACQCQADRWGARC-EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA-AARC 172
Query: 373 HPVTGACTCQPGWSGHHCNE----------------SCPVGYYGDGCQLPCTCQNGADCH 416
TGAC C+PGW G C+ +C G++G CQ C C G C
Sbjct: 173 EQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CS 231
Query: 417 SITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS-CNNGGTCSPVDGSC-TCKEGWQGL 474
+ +G CTC PGF G C + C AG++G C+ C C + CSP GSC +C+ GW G
Sbjct: 232 AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGT 291
Query: 475 DCTLPCPSGTWGLNCNESCT-CANGAACSPIDGSCS-CTPGWLGDTCELPCPDGTFGLNC 532
C PC GT+G +C + C C +G AC P G C C PGWLG CE PCP GTFG +C
Sbjct: 292 QCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDC 351
Query: 533 SEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG 592
C CD VTG C C AG+ G C+++CP G G NCSV C C G C P G
Sbjct: 352 GSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPE-GLCHPVSG 410
Query: 593 SCECAPGFR 601
SC+ G R
Sbjct: 411 SCQPGSGSR 419
Score = 281 bits (720), Expect = 2e-75
Identities = 145/412 (35%), Positives = 172/412 (41%), Gaps = 54/412 (13%)
Query: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
C GW + P+ C+ P CQ C G C C PGF G C+ C
Sbjct: 41 CCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQ 93
Query: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500
+GP+C C C+ G C P G+C C+ + WG C C C
Sbjct: 94 YWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWGARCEFPCACGPHGR 140
Query: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
C P G C C PGW TC PC T C + TG C C GW G
Sbjct: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGWWGR 188
Query: 561 RCD----------------STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPL 604
RC C PG WGP C C C G CS G C C PGFRG
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGFRGAR 247
Query: 605 CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE-CLPGFSGALCNQVCAGGYFGQDC 663
C+ CP G +G CA C C H + PC +G CE C PG++G C Q C G FG+ C
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKH-NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESC 306
Query: 664 AQLC-SCANNGTCSPIDGSCQ-CFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAE 721
Q C C + C P G CQ C PGW+G C CP G +G C C SC
Sbjct: 307 EQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTV 366
Query: 722 DGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTG 773
G C C+ G+ G C CPA F G +C C+C G C +SG C +G
Sbjct: 367 TGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSG 417
Score = 271 bits (692), Expect = 3e-72
Identities = 144/395 (36%), Positives = 168/395 (42%), Gaps = 54/395 (13%)
Query: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSP 503
P C +C C G C CK G+ G C+ CP WG +C ESC C C P
Sbjct: 55 PICEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEP 113
Query: 504 IDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGW------ 557
G+C C G CE PC G G CDP TG C C GW
Sbjct: 114 ATGACQCQADRWGARCEFPCACGPHGR-------------CDPATGVCHCEPGWWSSTCR 160
Query: 558 -------TGIRCDST-----CPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLC 605
RC+ C PG WG CS C+C +G C + G C C PG+ GP C
Sbjct: 161 RPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-HGSPCEQDSGRCACRPGWWGPEC 219
Query: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
Q+ C CV C SG C C PGF GA C C G G CA
Sbjct: 220 QQQCE--------------CVRGR--CSAASGECTCPPGFRGARCELPCPAGSHGVQCAH 263
Query: 666 LCS-CANNGTCSPIDGSCQ-CFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAED 722
C C +N CSP GSC+ C PGW G C Q C PG +G +C C C +G +C +
Sbjct: 264 SCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDT 323
Query: 723 GACH-CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQ 781
G C C PGW G C CP FG+DCG C SCD ++G C C G+ G C
Sbjct: 324 GHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNA 383
Query: 782 RCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPG 816
C G G C CEC C V+G+C G
Sbjct: 384 SCPAGFHGNNCSVPCEC-PEGLCHPVSGSCQPGSG 417
Score = 236 bits (602), Expect = 8e-62
Identities = 130/381 (34%), Positives = 163/381 (42%), Gaps = 63/381 (16%)
Query: 467 CKEGWQGLD--CTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCP 524
C GW+ D CT+P G +E C G C C PG+ G C CP
Sbjct: 41 CCAGWRQKDQECTIPICEGPDACQKDEVCVKP---------GLCRCKPGFFGAHCSSRCP 91
Query: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENG 584
+G +C E C C C+P TG C C A RWG C C+C
Sbjct: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCACGPH 138
Query: 585 GSCSPEDGSCECAPGFRGPLCQR------------------ICPPGFYGHGCAQPCPLCV 626
G C P G C C PG+ C+R +C PG++G C+ C
Sbjct: 139 GRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNC-- 196
Query: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFP 686
H S PC SG C C PG ++G +C Q C C G CS G C C P
Sbjct: 197 HGS-PCEQDSGRCACRPG-------------WWGPECQQQCECVR-GRCSAASGECTCPP 241
Query: 687 GWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGACH-CTPGWTGLFCTQRCPAAF 744
G+ G C CP G G C H+C C + CS + G+C C PGW G C Q C
Sbjct: 242 GFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGT 301
Query: 745 FGKDCGRVC-QCQNGASCDHISGKCT-CRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNS 802
FG+ C + C C++G +C+ +G C C G+ G CE C GTFG C C
Sbjct: 302 FGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQG 361
Query: 803 TCDHVTGTCYCSPGFKGIRCD 823
+CD VTG C CS G+ G C+
Sbjct: 362 SCDTVTGDCVCSAGYWGPSCN 382
Score = 159 bits (402), Expect = 1e-38
Identities = 83/227 (36%), Positives = 104/227 (45%), Gaps = 37/227 (16%)
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQC----------FP 686
G+C C PGF GA C+ C G Y+G DC + C C +G C P G+CQC FP
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 687 GWIGKD--CSQA-----CPPGFWGPACFHACSCHNGAS-CSAEDGACHCTPGWTGLFCTQ 738
G C A C PG+W C C C+ A+ C GAC C PGW G C+
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 739 RCPA----------------AFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQR 782
RC ++G +C + C+C G C SG+CTC GF G CE
Sbjct: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELP 251
Query: 783 CAPGTFGYGCQQLC-ECMNNSTCDHVTGTCY-CSPGFKGIRCDQAAL 827
C G+ G C C C +N C TG+C C PG+ G +C Q L
Sbjct: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCL 298
Score = 60.1 bits (144), Expect = 1e-08
Identities = 36/125 (28%), Positives = 46/125 (36%), Gaps = 11/125 (8%)
Query: 719 SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQH 778
S+ C GW Q C C CQ C G C C+ GF G H
Sbjct: 33 SSPSAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAH 85
Query: 779 CEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQAALMMEELNPYTKI 838
C RC +G C++ C C + C+ TG C C G RC+ P+ +
Sbjct: 86 CSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPC----ACGPHGRC 141
Query: 839 SPALG 843
PA G
Sbjct: 142 DPATG 146
Score = 56.6 bits (135), Expect = 1e-07
Identities = 29/75 (38%), Positives = 42/75 (56%), Gaps = 5/75 (6%)
Query: 96 GDFCIPLCTEECVHGRC--VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGAL 153
G+ C C CV G C V+ D C C G+ GP C++ C + G +CS C+C G L
Sbjct: 348 GEDCGSTCPT-CVQGSCDTVTGD-CVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEG-L 404
Query: 154 CNPITGACVCAAGFR 168
C+P++G+C +G R
Sbjct: 405 CHPVSGSCQPGSGSR 419
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 292 bits (748), Expect = 1e-78
Identities = 284/942 (30%), Positives = 347/942 (36%), Gaps = 298/942 (31%)
Query: 110 GRCVSPDT----CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAA 165
GRC + C C PGW G C D H GP C+ R CQ+ + +C C
Sbjct: 53 GRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP-CAGRGVCQSSVVAGTARFSCRCPR 110
Query: 166 GFRGWRCE--ELCAPGTHGKGCQLPCQCRHGASCDPRAGE---CLCAPGYTGVYCEELCP 220
GFRG C + C L C HGA C C C PGY G C
Sbjct: 111 GFRGPDCSLPDPC----------LSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCR---- 156
Query: 221 PGSHGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQP----------------- 261
S C + PC++GGTC + G C CP G+TG +C P
Sbjct: 157 --SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQ 214
Query: 262 ---------CPPGTFGQNCS---QDCP---CHHGGQC-DHV-TGQCHCTAGYMGDRCQEE 304
C PG GQNC DCP C +GG C D V T C C + G C E+
Sbjct: 215 SGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTYNCQCPPEWTGQFCTED 274
Query: 305 CPFGSFGFQCS-QHCDCHNGGQCSPTTG--ACECEPGYKGPRCQERL------------- 348
+C Q CHNGG C T G +C C G+ G C + +
Sbjct: 275 VD------ECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGAT 328
Query: 349 -----------CPEGLHGPGCTL--PC---PCDADNTISCHPVTG--ACTCQPGWSGHHC 390
CP G G C L C PC D +PV G CTC PG++G C
Sbjct: 329 CHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGAC 388
Query: 391 NE---------------------------SCPVGYYGDGCQ------LPCTCQNGADCHS 417
++ C GY G C+ L C+N A C
Sbjct: 389 DQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCLD 448
Query: 418 ITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSP-VDG-SCTCKEGWQG 473
G C C GF G C V C S C NGG C V+G SCTC G+ G
Sbjct: 449 RIGQFTCICMAGFTGTYCEVDI------DECQS-SPCVNGGVCKDRVNGFSCTCPSGFSG 501
Query: 474 LDCTL--------PCPSGTWGLNCNE--SCTCANGAA----------CSP--------ID 505
C L PC +G ++ + C CA G CSP +D
Sbjct: 502 STCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHGRCVD 561
Query: 506 G----SCSCTPGWLGDTCE-------------------------LPCPDGTFGLNCSEHC 536
G SC+C PG+ G CE CP GT G+NC +
Sbjct: 562 GIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNI 621
Query: 537 DCSHADGCDPVTGHCCCLAGWTGI-RCDSTCPPGRWGPNCSV------SCSCENGGSC-S 588
D ++ C G C GI R D C PG GP C+V S C GGSC
Sbjct: 622 DDCASNPC--TFGVC-----RDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVD 674
Query: 589 PEDG-SCECAPGFRGPLCQRICPPGFYGHGCA-QPCPLCVHSSRPCHHISG--ICECLPG 644
E+G C C PG PLC PP H CA +PC S C+ G C C PG
Sbjct: 675 GENGFRCLCPPGSLPPLC---LPP---SHPCAHEPC-----SHGICYDAPGGFRCVCEPG 723
Query: 645 FSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDG---SCQCFPGWIGKDCS--QACPP 699
+SG C+Q A +D + C GTCS DG C C PG G+ C C P
Sbjct: 724 WSGPRCSQSLA-----RDACESQPCRAGGTCSS-DGMGFHCTCPPGVQGRQCELLSPCTP 777
Query: 700 GFWGPACFHACSCHNGASCSAEDG---ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQ 756
C +G C + G C C GW G C Q +C C
Sbjct: 778 N----------PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV------DECAGPAPCG 821
Query: 757 NGASCDHISG--KCTCRTGFTGQHCEQ-------------------------RCAPGTFG 789
C +++G CTC G+TG C+Q C PG G
Sbjct: 822 PHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAG 881
Query: 790 YGC-QQLCECMNN----STC-DHVTG-TCYCSPGFKGIRCDQ 824
C + + EC++N TC DHV TC C PG+ G C+Q
Sbjct: 882 PRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ 923
Score = 276 bits (706), Expect = 7e-74
Identities = 277/979 (28%), Positives = 345/979 (35%), Gaps = 304/979 (31%)
Query: 88 CCPGYYESGDFC---IPLC-TEECVHG-RC---VSPDTCHCEPGWGGPDCSSGCDSDHWG 139
C PGY +G C + C ++ C HG +C V C C G G +C D
Sbjct: 570 CAPGY--TGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASN 627
Query: 140 PHCS--------NR--CQCQ---NGALCNPITGACV---------CAAGFRGWRCEELCA 177
P C+ NR C CQ G LCN C C G G+RC LC
Sbjct: 628 P-CTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRC--LCP 684
Query: 178 PGTHGKGCQLPCQ------CRHGASCDPRAG-ECLCAPGYTGVYCEELCPPGSHGAHCEL 230
PG+ C P C HG D G C+C PG++G C + + CE
Sbjct: 685 PGSLPPLCLPPSHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDA----CES 740
Query: 231 RCPCQNGGTCHH--ITGECACPPGWTGAVCA--QPCPPGTFGQNCSQDCPCHHGGQCDHV 286
+ PC+ GGTC + C CPPG G C PC P PC HGG+C+
Sbjct: 741 Q-PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPN----------PCEHGGRCESA 789
Query: 287 TGQ---CHCTAGYMGDRCQE---EC----PFGSFG--------FQCSQH----------- 317
GQ C C G+ G RCQ+ EC P G G F C+ H
Sbjct: 790 PGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQD 849
Query: 318 ---CD---CHNGGQCSPTTGA--CECEPGYKGPRCQERL--CPEGLHGPGCTLPCPCDAD 367
CD C NGG C G+ C C PG+ GPRC + C GPG
Sbjct: 850 INDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG---------- 899
Query: 368 NTISCHPVTGACTCQPGWSGHHCNESCP-----VGYYGDGC-----QLPCTCQ---NGAD 414
T + H + CTC PG+ G HC + P + G C C C+ GA
Sbjct: 900 -TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAH 958
Query: 415 CHSITGGCTCAPGFMGEVCAVS-------CAAGTYGPNCSSI---CS---CNNGGTCSPV 461
C C P G VC+ + C GP C ++ CS C NGG C
Sbjct: 959 CQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT 1018
Query: 462 DGSCTCKEGWQGLDC---TLPC--------------------------------PSGTWG 486
C C GW G C +LPC P G G
Sbjct: 1019 GAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTG 1078
Query: 487 LNCNESCT------CANGAACSPIDGS--CSCTPGWLGDTCE------------------ 520
+C + C +G C G C C PG+ GD CE
Sbjct: 1079 SHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCI 1138
Query: 521 -------LPCPDGTFGLNCSEHCD-------------CSHADGCDPVTG--HCCCLAGWT 558
CP GT G+ C + D C H C + G C C G+T
Sbjct: 1139 DLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYT 1198
Query: 559 GIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGS---CECAPGFRGPLCQRICPPGFYG 615
G+RC++ R G +C + C + G C C GF GP CQ +
Sbjct: 1199 GLRCEADINECRSG-----ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVL------ 1247
Query: 616 HGCAQPCPLCVHSSRPCHHISGICECLPGFSGAL---CNQVCAGGYFGQDCAQLCSCANN 672
PC S+PC H G C PG G L C+ CA ++G C ++
Sbjct: 1248 ----SPC-----ESQPCQH-GGQCRPSPGPGGGLTFTCH--CAQPFWGPRCERVARSCRE 1295
Query: 673 GTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC--------------FHACSCHNGASC 718
C P+ CQ P G C ACPPG GP+C A C +G SC
Sbjct: 1296 LQC-PVGVPCQQTPR--GPRC--ACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSC 1350
Query: 719 SAEDGA----CHCTPGWTGLFC-----------TQRCPAAFF-----GKDCGRVCQCQNG 758
A C C GWTG C RCP A + C R C N
Sbjct: 1351 RPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDREC---NS 1407
Query: 759 ASCDHISGKCTCRTGFTGQHCEQ-RCAPGTFGYGCQQLCE---CMNNSTCDHVTG---TC 811
C G C+ G + CE +C C C C+ ++ H G TC
Sbjct: 1408 PGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTC 1467
Query: 812 ------YCSPGFKGIRCDQ 824
YC+ F RCDQ
Sbjct: 1468 NPVYEKYCADHFADGRCDQ 1486
Score = 270 bits (690), Expect = 5e-72
Identities = 260/919 (28%), Positives = 324/919 (35%), Gaps = 277/919 (30%)
Query: 88 CCPGYYESGDFC---IPLCT---EECVH-GRCVSPD---TCHCEPGWGGPDCSSGCDSDH 137
C PG+ +G C + C+ C H GRCV+ C C G+ GP C + +
Sbjct: 379 CPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
Query: 138 WGPHCSNRCQCQNGALCNPITG--ACVCAAGFRGWRCEE--------------------- 174
GP C+N A C G C+C AGF G CE
Sbjct: 437 SGP-------CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVN 489
Query: 175 ----LCAPGTHGKGCQLPCQ------CRHGASC--DPRAGECLCAPGYTGVYCEE----- 217
C G G CQL CR+GA C P EC CA G+ G C+
Sbjct: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDC 549
Query: 218 -------------------LCPPGSHGAHCELRC------PCQNGGTCHHITGE--CACP 250
C PG G CE + PC++GG C + + C CP
Sbjct: 550 SPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLVDKYLCRCP 609
Query: 251 PGWTGAVC--------AQPCPPGTFGQNCSQ-DCPCHHGGQ---CDHVTGQC-------- 290
G TG C + PC G ++ DC C G C+ +C
Sbjct: 610 SGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEG 669
Query: 291 -HCTAGYMGDRCQEECPFGSFGFQC------SQHCDCHNGGQCSPTTGA--CECEPGYKG 341
C G G RC CP GS C H C +G C G C CEPG+ G
Sbjct: 670 GSCVDGENGFRCL--CPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAPGGFRCVCEPGWSG 726
Query: 342 PRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGD 401
PRC + L + PC A T S + CTC PG G C P
Sbjct: 727 PRCSQSLARDACESQ------PCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPC----- 775
Query: 402 GCQLPCTCQNGADCHSITGG---CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC 458
P C++G C S G C+C G+ G C C+ C G C
Sbjct: 776 ---TPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV------DECAGPAPCGPHGIC 826
Query: 459 SPVDG--SCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG--SCSCTPGW 514
+ + G SCTC G+ G PS +N + C NG +C G SCSC PG+
Sbjct: 827 TNLAGSFSCTCHGGYTG-------PSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF 879
Query: 515 LGDTC--------ELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTC 566
G C PC GT C++H + C C G+ G C+
Sbjct: 880 AGPRCARDVDECLSNPCGPGT----CTDHV----------ASFTCTCPPGYGGFHCEQDL 925
Query: 567 PPGRWGPNCSVSCSCENGGSC--SPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL 624
P+CS S SC NGG+C SC C PG+ G CQ A PC
Sbjct: 926 ------PDCSPS-SCFNGGTCVDGVNSFSCLCRPGYTGAHCQHE----------ADPC-- 966
Query: 625 CVHSSRPCHHISGICECL-PGFSGALCNQVCAGGYFGQDCAQL---CS---CANNGTCSP 677
SRPC H G+C PGF C + G C L CS C N G C
Sbjct: 967 ---LSRPCLH-GGVCSAAHPGF-----RCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQ 1017
Query: 678 IDGSCQCFPGWIGKDCSQACPPGFWGPACFHACS---------CHNGASCSAEDGA--CH 726
C C PGW G+ C P C A + C G C ED + C
Sbjct: 1018 TGAYCLCPPGWSGRLCDIRSLP------CREAAAQIGVRLEQLCQAGGQCVDEDSSHYCV 1071
Query: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQ--- 781
C G TG C Q D CQ+G +C G C C G+ G +CE
Sbjct: 1072 CPEGRTGSHCEQEV-------DPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVD 1124
Query: 782 ----------------------RCAPGTFGYGC---QQLC----------ECMNNSTCDH 806
C PGT G C + C C++N TC
Sbjct: 1125 ECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVD 1184
Query: 807 VTG--TCYCSPGFKGIRCD 823
+ G C C PG+ G+RC+
Sbjct: 1185 LVGGFRCTCPPGYTGLRCE 1203
Score = 268 bits (684), Expect = 3e-71
Identities = 267/991 (26%), Positives = 346/991 (34%), Gaps = 319/991 (32%)
Query: 102 LCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA- 160
+C V+GR + C C PG+ G C D G + C++ C G+
Sbjct: 365 ICDTNPVNGRAI----CTCPPGFTGGACDQDVDECSIGAN-----PCEHLGRCVNTQGSF 415
Query: 161 -CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE--CLCAPGYTGVYCEE 217
C C G+ G RCE T C L CR+ A+C R G+ C+C G+TG YCE
Sbjct: 416 LCQCGRGYTGPRCE------TDVNEC-LSGPCRNQATCLDRIGQFTCICMAGFTGTYCEV 468
Query: 218 -------------------------LCPPGSHGAHCEL------RCPCQNGGTCHHITG- 245
CP G G+ C+L PC+NG C
Sbjct: 469 DIDECQSSPCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDG 528
Query: 246 -ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG-QCHCTAGYMGDRCQE 303
EC C G+ G +C + +CS D PCHHG D + C C GY G RC+
Sbjct: 529 YECRCAEGFEGTLCDRNV------DDCSPD-PCHHGRCVDGIASFSCACAPGYTGTRCES 581
Query: 304 E-------------------------CPFGSFGFQCSQHCDCHNGGQCSPTTGACE---- 334
+ CP G+ G C + D C T G C
Sbjct: 582 QVDECRSQPCRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPC--TFGVCRDGIN 639
Query: 335 -----CEPGYKGPRCQER------------------------LCPEGLHGPGC---TLPC 362
C+PG+ GP C LCP G P C + PC
Sbjct: 640 RYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPC 699
Query: 363 PCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
+ + C+ G C C+PGWSG C++S D C+ C+ G C S
Sbjct: 700 AHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLA----RDACESQ-PCRAGGTCSSDGM 754
Query: 421 G--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS---CTCKEGWQGL- 474
G CTC PG G C + PN C +GG C G C+C +GWQG
Sbjct: 755 GFHCTCPPGVQGRQCELLSPCT---PN-----PCEHGGRCESAPGQLPVCSCPQGWQGPR 806
Query: 475 ------DCTLPCPSGTWGLNCNE----SCTC---------------------ANGAACSP 503
+C P P G G+ N SCTC NG +C
Sbjct: 807 CQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQD 866
Query: 504 IDGS--CSCTPGWLGDTCE------------------------LPCPDGTFGLNCSEHC- 536
GS CSC PG+ G C CP G G +C +
Sbjct: 867 GVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP 926
Query: 537 DCSHA---DGCDPVTG----HCCCLAGWTGIRCDS------------------------- 564
DCS + +G V G C C G+TG C
Sbjct: 927 DCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRC 986
Query: 565 TCPPGRWGPNCSVS---CS---CENGGSCSPEDGSCECAPGFRGPLCQR----------- 607
TC GP C CS C+NGG C C C PG+ G LC
Sbjct: 987 TCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQ 1046
Query: 608 ------------------------ICPPGFYGHGCAQPCPLCVHSSRPCHH-------IS 636
+CP G G C Q C+ ++PC H +
Sbjct: 1047 IGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL--AQPCQHGGTCRGYMG 1104
Query: 637 G-ICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS--CQCFPGWIGKDC 693
G +CECLPG++G C +CA C + G+C + C C PG +G C
Sbjct: 1105 GYMCECLPGYNGDNCEDDV------DECASQ-PCQHGGSCIDLVARYLCSCPPGTLGVLC 1157
Query: 694 S---QACPPG---FWGPACFHACSCHNGASCSAEDG-ACHCTPGWTGLFCTQRCPAAFFG 746
C PG GP C H NG G C C PG+TGL RC A
Sbjct: 1158 EINEDDCGPGPPLDSGPRCLH-----NGTCVDLVGGFRCTCPPGYTGL----RCEADI-- 1206
Query: 747 KDC-GRVCQCQNGASCDHISG---KCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNN- 801
+C C + C G +C C GF+G C+ +P CQ +C +
Sbjct: 1207 NECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCE-SQPCQHGGQCRPSP 1265
Query: 802 STCDHVTGTCYCSPGFKGIRCDQAALMMEEL 832
+T TC+C+ F G RC++ A EL
Sbjct: 1266 GPGGGLTFTCHCAQPFWGPRCERVARSCREL 1296
Score = 214 bits (545), Expect = 3e-55
Identities = 216/801 (26%), Positives = 265/801 (33%), Gaps = 245/801 (30%)
Query: 88 CCPGYYESGDFCIPLCTEE-CVHG-RCVSPD----TCHCEPGWGGPDC------------ 129
C PG + CT C HG RC S C C GW GP C
Sbjct: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAP 819
Query: 130 --------------SSGCDSDHWGPHCS---NRCQ---CQNGALCNPITGA--CVCAAGF 167
S C + GP C N C C NG C G+ C C GF
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF 879
Query: 168 RGWRCEE------------------------LCAPGTHGKGCQL------PCQCRHGASC 197
G RC C PG G C+ P C +G +C
Sbjct: 880 AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC 939
Query: 198 --DPRAGECLCAPGYTGVYCEE-----LCPPGSHG-----AHCELRC------------- 232
+ CLC PGYTG +C+ L P HG AH RC
Sbjct: 940 VDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT 999
Query: 233 --------PCQNGGTCHHITGECACPPGWTGAVC-----------AQ------------- 260
PCQNGG C C CPPGW+G +C AQ
Sbjct: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
Query: 261 -----------PCPPGTFGQNCSQDC------PCHHGGQCDHVTG--QCHCTAGYMGDRC 301
CP G G +C Q+ PC HGG C G C C GY GD C
Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
Query: 302 QEECPFGSFGFQCSQHCDCHNGGQCSPTTG--ACECEPGYKGPRCQERLCPEGLHGPGCT 359
+++ +C+ C +GG C C C PG G C+ E GPG
Sbjct: 1120 EDDVD------ECASQ-PCQHGGSCIDLVARYLCSCPPGTLGVLCE---INEDDCGPGPP 1169
Query: 360 LPCPCDADNTISCHPVTGA--CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHS 417
L + +C + G CTC PG++G C C++GA CH+
Sbjct: 1170 LDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADIN------------ECRSGA-CHA 1216
Query: 418 I-TGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS------CNNGGTCSPVDGSCTCKEG 470
T C PG G C C AG GP C ++ S C +GG C P G
Sbjct: 1217 AHTRDCLQDPG-GGFRCL--CHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGP------ 1267
Query: 471 WQGLDCTLPCPSGTWGLNCN---ESC---TCANGAAC--SPIDGSCSCTPGWLGDTCEL- 521
GL T C WG C SC C G C +P C+C PG G +C
Sbjct: 1268 GGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSF 1327
Query: 522 -PCPDGTFGLNCSEHCDCSHADGCDPVT----GHCCCLAGWTGIRCD------------- 563
P G +C+ C H C P C C GWTG RC+
Sbjct: 1328 PGSPPGASNASCAA-APCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPR 1386
Query: 564 ---STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRI-CPPGFYGHGCA 619
+ C R C C N C + G C + G C+ + C F C
Sbjct: 1387 CPRAACQAKRGDQRCDREC---NSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCD 1443
Query: 620 QPC--PLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP 677
C P C++ + CH C P + + CA + C Q C N C
Sbjct: 1444 PACSSPACLYDNFDCHAGGRERTCNPVY-----EKYCADHFADGRCDQGC---NTEEC-- 1493
Query: 678 IDGSCQCFPGWIGKDCSQACP 698
GW G DC+ P
Sbjct: 1494 ---------GWDGLDCASEVP 1505
Score = 146 bits (368), Expect = 1e-34
Identities = 165/643 (25%), Positives = 205/643 (31%), Gaps = 259/643 (40%)
Query: 88 CCPGYYESGDFCIPLCT---EECVHGRC--------VSPDTCHCEPGWGG-------PDC 129
C PG F P C +EC+ C V+ TC C PG+GG PDC
Sbjct: 875 CLPG------FAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDC 928
Query: 130 SSG------------------CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWR 171
S C + G HC + + L P VC+A G+R
Sbjct: 929 SPSSCFNGGTCVDGVNSFSCLCRPGYTGAHCQHEA---DPCLSRPCLHGGVCSAAHPGFR 985
Query: 172 CEELCAPGTHGKGCQLPCQ------CRHGASCDPRAGECLCAPGYTGVYCEE-------- 217
C C G CQ C++G C CLC PG++G C+
Sbjct: 986 CT--CLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREA 1043
Query: 218 ---------------------------LCPPGSHGAHCE------LRCPCQNGGTCHHIT 244
+CP G G+HCE L PCQ+GGTC
Sbjct: 1044 AAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYM 1103
Query: 245 GE--CACPPGWTGAVC--------AQPC-----------------PPGTFGQNCS---QD 274
G C C PG+ G C +QPC PPGT G C D
Sbjct: 1104 GGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDD 1163
Query: 275 CP----------CHHGGQCDHVTG--QCHCTAGYMGDRCQ---EECPFGSF--------- 310
C C H G C + G +C C GY G RC+ EC G+
Sbjct: 1164 CGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCL 1223
Query: 311 -----GFQCSQH--------------CD---CHNGGQCSPTTG-------ACECEPGYKG 341
GF+C H C+ C +GGQC P+ G C C + G
Sbjct: 1224 QDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWG 1283
Query: 342 PRCQERL------------------------CPEGLHGPGC-TLP-CPCDADNTI----- 370
PRC+ CP GL GP C + P P A N
Sbjct: 1284 PRCERVARSCRELQCPVGVPCQQTPRGPRCACPPGLSGPSCRSFPGSPPGASNASCAAAP 1343
Query: 371 -----SCHPVTGA----CTCQPGWSGHHCNESCPVGYYGDGCQLP-CTCQ---------- 410
SC P A C C GW+G C + + P CQ
Sbjct: 1344 CLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDR 1403
Query: 411 --NGADCHSITGGCTCAPGFMGEVC-AVSCAAGTYGPNCSSICS----------CNNGG- 456
N C G C+ + G C A+ C C CS C+ GG
Sbjct: 1404 ECNSPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGR 1463
Query: 457 --TCSPV--------------DGSCTCKE-GWQGLDCTLPCPS 482
TC+PV D C +E GW GLDC P+
Sbjct: 1464 ERTCNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPA 1506
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 285 bits (729), Expect = 2e-76
Identities = 268/994 (26%), Positives = 334/994 (33%), Gaps = 323/994 (32%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTC----------HCEPGWGGPDCSSGCDSDH 137
C G+ SG C+ C+ C + TC C PGW G C
Sbjct: 89 CALGF--SGPLCLTPLDNACLTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQA----- 141
Query: 138 WGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC--------QLPC 189
P SN C NG C P + +C C P HG C Q P
Sbjct: 142 -DPCASN--PCANGGQCLPFEASYICH-----------CPPSFHGPTCRQDVNECGQKPG 187
Query: 190 QCRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH---HIT 244
CRHG +C G C+C +TG CE P S PCQNGGTC +T
Sbjct: 188 LCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPS-------PCQNGGTCRPTGDVT 240
Query: 245 GECACPPGWTGAVCAQ-------------------------PCPPGTFGQNCSQDC---- 275
ECAC PG+TG C + CPP GQ C++D
Sbjct: 241 HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ 300
Query: 276 ----PCHHGGQCDHVTG--QCHCTAGYMGDRCQE-------------------------E 304
C +GG C + G C C G+ G+ C E E
Sbjct: 301 LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE 360
Query: 305 CPFGSFGFQC--SQHC---DCHNGGQC--SPTTG--ACECEPGYKGPRCQERL------- 348
CP G G C + C C+ G C +P G C C GY GP C + +
Sbjct: 361 CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA 420
Query: 349 -------------------CPEGLHGPGCTLPC------PCDADNTISCHPVTGACTCQP 383
C +G GP C + PC D T C C P
Sbjct: 421 NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP 480
Query: 384 GWSGHHC----------------------NE---SCPVGYYGDGCQ------LPCTCQNG 412
G+ G HC NE CP G+ G CQ C+NG
Sbjct: 481 GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG 540
Query: 413 ADC--HSITGGCTCAPGFMGEVCAVS------------------------CAAGTYGPNC 446
A C T C C G+ G C V C G G +C
Sbjct: 541 AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC 600
Query: 447 S---SICS---CNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
+ CS C +GGTC D + C C +G G +C + L+ S C +G
Sbjct: 601 ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEI-------NLDDCASSPCDSG 653
Query: 499 AACSPIDG-SCSCTPGWLGDTCEL--------------PCPDGTFGLNC------SEHCD 537
IDG C+C PG+ G C + C DG G C +
Sbjct: 654 TCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTC 713
Query: 538 CSHADGCDP-VTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV------SCSCENGGSCSPE 590
S + C+ H C G +CD C PG G NC + S C NGG+C
Sbjct: 714 LSEVNECNSNPCVHGACRDSLNGYKCD--CDPGWSGTNCDINNNECESNPCVNGGTCKDM 771
Query: 591 DGS--CECAPGFRGPLCQR--------------ICPPGFYGHGCAQPCPLCVHSSRPCHH 634
C C GF GP CQ C G+ C P ++ C
Sbjct: 772 TSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLP---YTGATCEV 828
Query: 635 ISGICECLPGFSGALCNQ---------VCAGGYFGQDC------AQLCSCANNGTCSPID 679
+ C P +G C Q VC G+ GQ C L C + +C
Sbjct: 829 VLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTH 888
Query: 680 GS--CQCFPGWIGKDCS---QACPPGFWGPACFHACSCHNGASCS--AEDGACHCTPGWT 732
G C C G+ G++C C P CHNG SC+ C C PG+
Sbjct: 889 GGYRCHCQAGYSGRNCETDIDDCRPN----------PCHNGGSCTDGINTAFCDCLPGFR 938
Query: 733 GLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI--SGKCTCRTGFTGQHCEQRCAPGTFGY 790
G FC + +C C+NGA+C S CTC GF+G HCE T
Sbjct: 939 GTFCEEDI------NECAS-DPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTES- 990
Query: 791 GCQQLCECMNNSTC-DHVTG-TCYCSPGFKGIRC 822
C N TC D + TC C PGF G C
Sbjct: 991 ------SCFNGGTCVDGINSFTCLCPPGFTGSYC 1018
Score = 285 bits (728), Expect = 2e-76
Identities = 250/838 (29%), Positives = 317/838 (37%), Gaps = 234/838 (27%)
Query: 88 CCPGYYESGDFCIPLCTEECV------HGRC---VSPDTCHCEPGWGGPDCSSGCDSDHW 138
C PGY G C + T+EC +GRC ++ C C G+ G C D
Sbjct: 478 CMPGY--EGVHC-EVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDE--- 531
Query: 139 GPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRCE---ELCAPGTHGKGCQLPCQCRH 193
C++ C+NGA C P T CVC G+ G CE + C P PC H
Sbjct: 532 ---CAST-PCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPD--------PC---H 576
Query: 194 GASCDPRAGE--CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPP 251
SC CLC PGYTG +CE ++ C + PC++GGTC C
Sbjct: 577 YGSCKDGVATFTCLCRPGYTGHHCE------TNINECSSQ-PCRHGGTCQDRDNAYLCF- 628
Query: 252 GWTGAVCAQPCPPGTFGQNCS---QDC---PCHHGGQCDHVTG-QCHCTAGYMGDRCQEE 304
C GT G NC DC PC G D + G +C C GY G C
Sbjct: 629 ----------CLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNIN 678
Query: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC-P 363
+C+ + CHNGG C E G G C+ CPEG H P C
Sbjct: 679 ID------ECAGN-PCHNGGTC---------EDGINGFTCR---CPEGYHDPTCLSEVNE 719
Query: 364 CDADNTI--SCHPVTGA--CTCQPGWSGHHC---NESCPVGYYGDGCQLPCTCQNGADCH 416
C+++ + +C C C PGWSG +C N C C NG C
Sbjct: 720 CNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNNECESN----------PCVNGGTCK 769
Query: 417 SITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC-SPVDG-SCTCKEGWQ 472
+T G CTC GF G C + P C N GTC V G C C +
Sbjct: 770 DMTSGYVCTCREGFSGPNCQTNINECASNP-------CLNQGTCIDDVAGYKCNCLLPYT 822
Query: 473 GLDCTL---PCPSGTWGLNCNESCTCANGAACSPIDG----SCSCTPGWLGDTCELPCPD 525
G C + PC C NG C + SC C GW G TCE+
Sbjct: 823 GATCEVVLAPCAPSP----------CRNGGECRQSEDYESFSCVCPTGWQGQTCEV---- 868
Query: 526 GTFGLNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
+N C H C G C C AG++G C++ R P C N
Sbjct: 869 ---DINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP-------CHN 918
Query: 584 GGSCSP--EDGSCECAPGFRGPLCQR-------------------------ICPPGFYGH 616
GGSC+ C+C PGFRG C+ CP GF G
Sbjct: 919 GGSCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGI 978
Query: 617 GCAQPCPLCVHSSRPCHH----ISGI----CECLPGFSGALCNQVCAGGYFGQDCAQLCS 668
C P C SS C + + GI C C PGF+G+ C + +C
Sbjct: 979 HCENNTPDCTESS--CFNGGTCVDGINSFTCLCPPGFTGSYCQ------HDVNECDSQ-P 1029
Query: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC---FHACS---CHNGASC--SA 720
C + GTC GS +C CP G+ GP C H C C NG C +
Sbjct: 1030 CLHGGTCQDGCGSYRC-----------TCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTH 1078
Query: 721 EDGACHCTPGWTGLFC---TQRCPAAF--FGKDCGRVCQ----CQNGASCDHISGKCTCR 771
C C GWTGL+C + C A G D R+CQ C + + H C C+
Sbjct: 1079 TQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHH----CRCQ 1134
Query: 772 TGFTGQHCE---QRCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCDQ 824
G+TG +CE C+P C N +TC G +C C G+ G+ C +
Sbjct: 1135 AGYTGSYCEDLVDECSPS----------PCQNGATCTDYLGGYSCKCVAGYHGVNCSE 1182
Score = 280 bits (716), Expect = 5e-75
Identities = 278/1038 (26%), Positives = 358/1038 (34%), Gaps = 339/1038 (32%)
Query: 78 LRTMYRRRSQCCPGYYESGDFCI---PLCTEECVHG-RCVSPDT---CHCEPGWGGPDCS 130
L T+ + +C PG+ SG C P + C +G +C+ + CHC P + GP C
Sbjct: 119 LLTLTEYKCRCPPGW--SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCR 176
Query: 131 SG---------------------------CDSDHWGPHCS------NRCQCQNGALCNP- 156
C + H GP+C + CQNG C P
Sbjct: 177 QDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPT 236
Query: 157 --ITGACVCAAGFRGWRCEELC--APGTHGKGCQLPCQCRHGASCDPRAG--ECLCAPGY 210
+T C C GF G CEE PG + C++G +C C C P +
Sbjct: 237 GDVTHECACLPGFTGQNCEENIDDCPGNN---------CKNGGACVDGVNTYNCRCPPEW 287
Query: 211 TGVYCEELCPPGSHGAHCELRC-PCQNGGTCHHITG--ECACPPGWTGAVCAQ------- 260
TG YC E C+L CQNGGTCH+ G C C GWTG C++
Sbjct: 288 TGQYCTEDVD------ECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCAS 341
Query: 261 ------------------PCPPGTFGQNC--SQDC---PCHHGGQCDH--VTGQ--CHCT 293
CP G G C + C PC+ G CD V G+ C C
Sbjct: 342 AACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCP 401
Query: 294 AGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPE 351
+GY G C ++ S G C + G+C T G+ C+C GY GPRC+
Sbjct: 402 SGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQCLQGYTGPRCE------ 450
Query: 352 GLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC--------------------- 390
+ C + PC D T C C PG+ G HC
Sbjct: 451 -IDVNEC-VSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDK 508
Query: 391 -NE---SCPVGYYGDGCQLPCT------CQNGADCHS--ITGGCTCAPGFMGEVCAVS-- 436
NE CP G+ G CQ C+NGA C T C C G+ G C V
Sbjct: 509 INEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDID 568
Query: 437 ----------------------CAAGTYGPNCSSI---CS---CNNGGTCSPVDGS--CT 466
C G G +C + CS C +GGTC D + C
Sbjct: 569 ECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCF 628
Query: 467 CKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG-SCSCTPGWLGDTCEL---- 521
C +G G +C + L+ S C +G IDG C+C PG+ G C +
Sbjct: 629 CLKGTTGPNCEI-------NLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDE 681
Query: 522 ----------PCPDGTFGLNCS------EHCDCSHADGCDP-VTGHCCCLAGWTGIRCDS 564
C DG G C + S + C+ H C G +CD
Sbjct: 682 CAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCD- 740
Query: 565 TCPPGRWGPNCSV------SCSCENGGSCSPEDGS--CECAPGFRGPLCQR--------- 607
C PG G NC + S C NGG+C C C GF GP CQ
Sbjct: 741 -CDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNP 799
Query: 608 -----ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQ---------V 653
C G+ C P ++ C + C P +G C Q V
Sbjct: 800 CLNQGTCIDDVAGYKCNCLLP---YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCV 856
Query: 654 CAGGYFGQDC------AQLCSCANNGTCSPIDGS--CQCFPGWIGKDCS---QACPPGFW 702
C G+ GQ C L C + +C G C C G+ G++C C P
Sbjct: 857 CPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPN-- 914
Query: 703 GPACFHACSCHNGASCSAEDGA----CHCTPGWTGLFC---------------------- 736
CHNG SC+ DG C C PG+ G FC
Sbjct: 915 --------PCHNGGSCT--DGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCV 964
Query: 737 ---TQRCPAAFFGKDCGR------VCQCQNGASC-DHISG-KCTCRTGFTGQHCEQ---- 781
T CPA F G C C NG +C D I+ C C GFTG +C+
Sbjct: 965 DSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNE 1024
Query: 782 ---------------------RCAPGTFGYGCQQL---CE---CMNNSTC--DHVTGTCY 812
C G G CQ L C+ C N C H C
Sbjct: 1025 CDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCE 1084
Query: 813 CSPGFKGIRCDQAALMME 830
C G+ G+ CD ++ E
Sbjct: 1085 CPSGWTGLYCDVPSVSCE 1102
Score = 279 bits (714), Expect = 9e-75
Identities = 258/856 (30%), Positives = 323/856 (37%), Gaps = 260/856 (30%)
Query: 139 GPHCSNRCQ-CQNGALCNPITG--ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGA 195
GP CS + C NG C G ACVC F G RC++ C L C++
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQD-------PNPC-LSTPCKNAG 72
Query: 196 SCD--PRAG----ECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHIT---GE 246
+C R G C CA G++G C L P + C L PC+NGGTC +T +
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPLC--LTPLDNA---C-LTNPCRNGGTCDLLTLTEYK 126
Query: 247 CACPPGWTGAVCAQP------------------------CPPGTFGQNCSQDCP------ 276
C CPPGW+G C Q CPP G C QD
Sbjct: 127 CRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKP 186
Query: 277 --CHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT--- 329
C HGG C + G +C C A + G C E P+ CS C NGG C PT
Sbjct: 187 GLCRHGGTCHNEVGSYRCVCRATHTGPNC--ERPY----VPCSP-SPCQNGGTCRPTGDV 239
Query: 330 TGACECEPGYKGPRCQERL--CPEGLHGPGCTLPCPC-DADNTISCHPVTGACTCQPGWS 386
T C C PG+ G C+E + CP G C C D NT +C C P W+
Sbjct: 240 THECACLPGFTGQNCEENIDDCP----GNNCKNGGACVDGVNTYNCR-------CPPEWT 288
Query: 387 GHHCNESCPVGYYGDGCQL-PCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYG 443
G +C E D CQL P CQNG CH+ GG C C G+ GE C+ +
Sbjct: 289 GQYCTEDV------DECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENI------ 336
Query: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC--NESC---TCANG 498
+C+S +C +G TC S C+ CP G GL C N++C C G
Sbjct: 337 DDCAS-AACFHGATCHDRVASFYCE-----------CPHGRTGLLCHLNDACISNPCNEG 384
Query: 499 AAC--SPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG--HCC 552
+ C +P++G C+C G+ G C + + G N C HA C G C
Sbjct: 385 SNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGAN-----PCEHAGKCINTLGSFECQ 439
Query: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG--SCECAPGFRGPLC----- 605
CL G+TG RC+ N VS C+N +C + G C C PG+ G C
Sbjct: 440 CLQGYTGPRCEIDV-------NECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTD 492
Query: 606 --------------------QRICPPGFYGHGCAQPCPLCVHSSRPCHH----ISG---- 637
Q CP GF GH C C +S PC + + G
Sbjct: 493 ECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDEC--ASTPCKNGAKCLDGPNTY 550
Query: 638 ICECLPGFSGALCNQ------------------------VCAGGYFGQDC---AQLCS-- 668
C C G++G C +C GY G C CS
Sbjct: 551 TCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQ 610
Query: 669 -CANNGTCSPIDGS--CQCFPGWIGKDC------------------------SQACPPGF 701
C + GTC D + C C G G +C AC PG+
Sbjct: 611 PCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGY 670
Query: 702 WGPAC---FHACS---CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDC-GRVCQ 754
G C C+ CHNG +C EDG G C RCP + C V +
Sbjct: 671 TGSMCNINIDECAGNPCHNGGTC--EDGI-------NGFTC--RCPEGYHDPTCLSEVNE 719
Query: 755 CQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGC---QQLCE---CMNNSTCDHVT 808
C N C H CR G C+ C PG G C CE C+N TC +T
Sbjct: 720 C-NSNPCVH----GACRDSLNGYKCD--CDPGWSGTNCDINNNECESNPCVNGGTCKDMT 772
Query: 809 G--TCYCSPGFKGIRC 822
C C GF G C
Sbjct: 773 SGYVCTCREGFSGPNC 788
Score = 202 bits (515), Expect = 1e-51
Identities = 221/781 (28%), Positives = 264/781 (33%), Gaps = 177/781 (22%)
Query: 85 RSQCCPGYYESGDFC---IPLCTEECVH--GRC---VSPDTCHCEPGWGGPDCSSG---C 133
R C GY SG C I C H G C ++ C C PG+ G C C
Sbjct: 892 RCHCQAGY--SGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEEDINEC 949
Query: 134 DSDHWGPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELCAPGTHGKGCQLPCQC 191
SD C+NGA C + C C AGF G CE T C
Sbjct: 950 ASD----------PCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESS-------C 992
Query: 192 RHGASCDPRAGE--CLCAPGYTGVYCEE-------------------------LCPPGSH 224
+G +C CLC PG+TG YC+ CP G
Sbjct: 993 FNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYT 1052
Query: 225 GAHCEL------RCPCQNGGTC--HHITGECACPPGWTGAVCAQP---CPPGTFGQNCSQ 273
G +C+ PC+NGG C H C CP GWTG C P C Q
Sbjct: 1053 GPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDV 1112
Query: 274 DCPCHHGGQCDHV--TGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTG 331
C HGG C T C C AGY G C++ +CS C NG C+ G
Sbjct: 1113 ARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVD------ECSP-SPCQNGATCTDYLG 1165
Query: 332 --ACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
+C+C GY G C E + L PC T P T C+C G G H
Sbjct: 1166 GYSCKCVAGYHGVNCSEEIDE--------CLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 390 CNESCPVGYYGDGCQLPC-------TCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAG 440
C + D C P C N C GG CTC PGF+GE C G
Sbjct: 1218 CEINV------DDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERC-----EG 1266
Query: 441 TYGPNCSSICSCNNGGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
S+ C C D C C+ G G C +G G C TCA
Sbjct: 1267 DVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCE-SVINGCKGKPCKNGGTCA-- 1323
Query: 499 AACSPIDG-SCSCTPGWLGDTCELPCPDGTFGLNCSEHCD---CSHADGC--DPVTGHCC 552
A + G C C G+ G TCE N + C C + C P + C
Sbjct: 1324 VASNTARGFICKCPAGFEGATCE----------NDARTCGSLRCLNGGTCISGPRSPTCL 1373
Query: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGS----CECAPGFRGPLCQRI 608
CL +TG C G N C N G+C P S C C F G LC +
Sbjct: 1374 CLGPFTGPECQFPASSPCLGGN-----PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHIL 1428
Query: 609 CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS 668
G G P PL I CE LP N+VC+
Sbjct: 1429 DYSFGGGAGRDIPPPL----------IEEACE-LPECQEDAGNKVCS-----------LQ 1466
Query: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQA--CPPGFWGPACFHACSCHNGASCSAEDGACH 726
C NN C G C K+C+Q+ C F C C N A C + C
Sbjct: 1467 C-NNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQC---NSAGCLFDGFDCQ 1522
Query: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPG 786
G Q C F C + C N A C+ C +H +R A G
Sbjct: 1523 RAEGQCNPLYDQYCKDHFSDGHCDQGC---NSAECEWDGLDC-------AEHVPERLAAG 1572
Query: 787 T 787
T
Sbjct: 1573 T 1573
Score = 112 bits (281), Expect = 1e-24
Identities = 89/274 (32%), Positives = 116/274 (42%), Gaps = 59/274 (21%)
Query: 572 GPNCSVSC-SCENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHS 628
GP CS +C NGG C +G+ C C F GP CQ P + PC +
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPC------LSTPCK----N 70
Query: 629 SRPCHHIS--GI----CECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPI--- 678
+ CH + G+ C C GFSG LC D A L + C N GTC +
Sbjct: 71 AGTCHVVDRRGVADYACSCALGFSGPLCLTPL-------DNACLTNPCRNGGTCDLLTLT 123
Query: 679 DGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA--CHCTPGWTGLFC 736
+ C+C PGW GK C QA P + C NG C + + CHC P + G C
Sbjct: 124 EYKCRCPPGWSGKSCQQADPCA--------SNPCANGGQCLPFEASYICHCPPSFHGPTC 175
Query: 737 TQRCPAAFFGKDCG-RVCQCQNGASCDHISG--KCTCRTGFTGQHCEQRCAPGTFGYGCQ 793
Q +CG + C++G +C + G +C CR TG +CE+ P C
Sbjct: 176 RQDV------NECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVP------CS 223
Query: 794 QLCECMNNSTC---DHVTGTCYCSPGFKGIRCDQ 824
C N TC VT C C PGF G C++
Sbjct: 224 P-SPCQNGGTCRPTGDVTHECACLPGFTGQNCEE 256
Score = 52.0 bits (123), Expect = 3e-06
Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 34/139 (24%)
Query: 703 GPACFHAC-SCHNGASCSAEDG--ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGA 759
GP C +C NG C A +G AC C + G C P C+N
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNPCLS--------TPCKNAG 72
Query: 760 SCDHISGK------CTCRTGFTGQHC----EQRCAPGTFGYGCQQLCECMNNSTCDHVTG 809
+C + + C+C GF+G C + C C N TCD +T
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNP----------CRNGGTCDLLTL 122
Query: 810 T---CYCSPGFKGIRCDQA 825
T C C PG+ G C QA
Sbjct: 123 TEYKCRCPPGWSGKSCQQA 141
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 285 bits (728), Expect = 2e-76
Identities = 147/437 (33%), Positives = 184/437 (42%), Gaps = 69/437 (15%)
Query: 380 TCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAA 439
TC GW + C + C+ TC C G C C G+ G C C
Sbjct: 63 TCCAGWRQQ--GDECGIAV----CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPR 115
Query: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA 499
+GP+C +CSC+ G C V G CTC + WG C +C C +G
Sbjct: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCH-------------ARRWGARCEHACQCQHGT 162
Query: 500 ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTG 559
C P G+C C PGW +G C+ C CS CDP TG C C AGW
Sbjct: 163 -CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW-- 206
Query: 560 IRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCA 619
WG +C+ C+C N C + G C+C G C R C F G
Sbjct: 207 -----------WGRSCNNQCAC-NSSPCEQQSGRCQCRERTFGARCDRYCQC-FRGR--- 250
Query: 620 QPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPI 678
CH + G C C PG+ G C + C G++G C + C C C+
Sbjct: 251 ------------CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
Query: 679 DGSC-QCFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGAC-HCTPGWTGLF 735
+G C C PGW G C Q C GF+G C H C C +G +C+ G C C GW G
Sbjct: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
Query: 736 CTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQL 795
C +C +G+DC VC CD SG+C C G G HC C PG G C Q
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
Query: 796 CECMNNSTCDHVTGTCY 812
C C + TCD VTG C+
Sbjct: 419 CSC-HEDTCDPVTGACH 434
Score = 268 bits (685), Expect = 2e-71
Identities = 142/401 (35%), Positives = 175/401 (43%), Gaps = 54/401 (13%)
Query: 88 CCPGYYESGDFC-IPLC--TEECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143
CC G+ + GD C I +C C CV P C C G+ G +C + C WGP C
Sbjct: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
Query: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE 203
C C C +TG C C A G RCE C QC+HG +C PR+G
Sbjct: 124 ELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC-------------QCQHG-TCHPRSGA 169
Query: 204 CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP 263
C C PG+ G A C C C C TG C C GW G C C
Sbjct: 170 CRCEPGWWG-------------AQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCA 216
Query: 264 PG----------------TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPF 307
TFG C + C C G +C V G C C GY G C+E CP
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 308 GSFGFQCSQHC-DCHNGGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
G +G C + C C C+ G C CEPG+ G +C + C G +G GC+ CP
Sbjct: 276 GFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP-CATGFYGEGCSHRCPPC 334
Query: 366 ADNTISCHPVTGACT-CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTC 424
D +C+ VTG CT C GW G C C G YG+ C C C +G C C
Sbjct: 335 RDGH-ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLC 393
Query: 425 APGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
+PG G C V+C G +G +C+ CSC+ TC PV G+C
Sbjct: 394 SPGVHGPHCNVTCPPGLHGADCAQACSCHE-DTCDPVTGAC 433
Score = 263 bits (672), Expect = 6e-70
Identities = 131/385 (34%), Positives = 175/385 (45%), Gaps = 52/385 (13%)
Query: 364 CDADNTISCHPVT---GACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
C+ ++T S + V G C C+ G+ G +C+ CP ++G C+ C+C C +TG
Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
CTC A +G C C C +G TC P G+C C+ GW
Sbjct: 140 QCTCH-------------ARRWGARCEHACQCQHG-TCHPRSGACRCEPGW--------- 176
Query: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE----------------LPCP 524
WG C +C C+ + C P G+C C GW G +C C
Sbjct: 177 ----WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCS-CEN 583
+ TFG C +C C C PV G C C G+ G C CP G +G C C C+
Sbjct: 233 ERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 584 GGSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC-EC 641
C+ +G C C PG+ G C + C GFYG GC+ CP C C+H++G C C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC-RDGHACNHVTGKCTRC 350
Query: 642 LPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGF 701
G+ G C C+ G +G+DCA +C+ +G C G C C PG G C+ CPPG
Sbjct: 351 NAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGL 410
Query: 702 WGPACFHACSCHNGASCSAEDGACH 726
G C ACSCH +C GACH
Sbjct: 411 HGADCAQACSCHED-TCDPVTGACH 434
Score = 250 bits (638), Expect = 6e-66
Identities = 150/468 (32%), Positives = 205/468 (43%), Gaps = 88/468 (18%)
Query: 466 TCKEGW--QGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPC 523
TC GW QG +C + C + TC+ C G C C G+ G C+ C
Sbjct: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 524 PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
P +G +C E C C C+ VTG C TC RWG C +C C++
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQC-------------TCHARRWGARCEHACQCQH 160
Query: 584 GGSCSPEDGSCECAPGFRGPLCQR-----------------ICPPGFYGHGCAQPCPLCV 626
G +C P G+C C PG+ G C +C G++G C C
Sbjct: 161 G-TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCAC-- 217
Query: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFP 686
+S PC SG C+C GA C++ C C + G C P+DG+C C P
Sbjct: 218 -NSSPCEQQSGRCQCRERTFGARCDRYC-------QCFR-------GRCHPVDGTCACEP 262
Query: 687 GWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGAC-HCTPGWTGLFCTQRCPAAF 744
G+ GK C + CP GF+G C C C C+ +G C C PGW G C Q C F
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF 322
Query: 745 FGKDCGRVCQ-CQNGASCDHISGKCT-CRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNS 802
+G+ C C C++G +C+H++GKCT C G+ G CE +C+ GT+G C +C +
Sbjct: 323 YGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG 382
Query: 803 TCDHVTGTCYCSPGFKGIRCD-------------QAALMMEE-LNPYTKISPALGAERHS 848
CD +G C CSPG G C+ QA E+ +P T +R
Sbjct: 383 HCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKG 442
Query: 849 V-GAVTGIMLLLFLIVVLLGLFAWHR----------RRQKEKGRDLAP 885
V GA ++LL+ L++ LLG R RR+ GR AP
Sbjct: 443 VMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRPRPRRELSLGRKKAP 490
Score = 196 bits (497), Expect = 1e-49
Identities = 102/300 (34%), Positives = 131/300 (43%), Gaps = 53/300 (17%)
Query: 87 QCCPGYYESGDFCIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGC------------ 133
QC G C C +C HG C C CEPGW G C+S C
Sbjct: 140 QCTCHARRWGARCEHAC--QCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQT 197
Query: 134 -----DSDHWGPHCSNRCQCQNGAL----------------------------CNPITGA 160
+ WG C+N+C C + C+P+ G
Sbjct: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
Query: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPC-QCRHGASCDPRAGECL-CAPGYTGVYCEEL 218
C C G+RG C E C G +G GC+ C QC+ C G CL C PG+ G C++
Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
Query: 219 CPPGSHGAHCELRCP-CQNGGTCHHITGECA-CPPGWTGAVCAQPCPPGTFGQNCSQDCP 276
C G +G C RCP C++G C+H+TG+C C GW G C C GT+G++C+ C
Sbjct: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
Query: 277 CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
G CD +G+C C+ G G C CP G G C+Q C CH C P TGAC E
Sbjct: 378 DCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACHLE 436
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 285 bits (728), Expect = 2e-76
Identities = 147/437 (33%), Positives = 184/437 (42%), Gaps = 69/437 (15%)
Query: 380 TCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAA 439
TC GW + C + C+ TC C G C C G+ G C C
Sbjct: 63 TCCAGWRQQ--GDECGIAV----CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKCPR 115
Query: 440 GTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA 499
+GP+C +CSC+ G C V G CTC + WG C +C C +G
Sbjct: 116 QFWGPDCKELCSCHPHGQCEDVTGQCTCH-------------ARRWGARCEHACQCQHGT 162
Query: 500 ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTG 559
C P G+C C PGW +G C+ C CS CDP TG C C AGW
Sbjct: 163 -CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW-- 206
Query: 560 IRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCA 619
WG +C+ C+C N C + G C+C G C R C F G
Sbjct: 207 -----------WGRSCNNQCAC-NSSPCEQQSGRCQCRERTFGARCDRYCQC-FRGR--- 250
Query: 620 QPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS-CANNGTCSPI 678
CH + G C C PG+ G C + C G++G C + C C C+
Sbjct: 251 ------------CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVA 298
Query: 679 DGSC-QCFPGWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGAC-HCTPGWTGLF 735
+G C C PGW G C Q C GF+G C H C C +G +C+ G C C GW G
Sbjct: 299 EGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDR 358
Query: 736 CTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQL 795
C +C +G+DC VC CD SG+C C G G HC C PG G C Q
Sbjct: 359 CETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQA 418
Query: 796 CECMNNSTCDHVTGTCY 812
C C + TCD VTG C+
Sbjct: 419 CSC-HEDTCDPVTGACH 434
Score = 268 bits (685), Expect = 2e-71
Identities = 142/401 (35%), Positives = 175/401 (43%), Gaps = 54/401 (13%)
Query: 88 CCPGYYESGDFC-IPLC--TEECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCS 143
CC G+ + GD C I +C C CV P C C G+ G +C + C WGP C
Sbjct: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
Query: 144 NRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGE 203
C C C +TG C C A G RCE C QC+HG +C PR+G
Sbjct: 124 ELCSCHPHGQCEDVTGQCTCHARRWGARCEHAC-------------QCQHG-TCHPRSGA 169
Query: 204 CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP 263
C C PG+ G A C C C C TG C C GW G C C
Sbjct: 170 CRCEPGWWG-------------AQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCA 216
Query: 264 PG----------------TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPF 307
TFG C + C C G +C V G C C GY G C+E CP
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 308 GSFGFQCSQHC-DCHNGGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLHGPGCTLPCPCD 365
G +G C + C C C+ G C CEPG+ G +C + C G +G GC+ CP
Sbjct: 276 GFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP-CATGFYGEGCSHRCPPC 334
Query: 366 ADNTISCHPVTGACT-CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTC 424
D +C+ VTG CT C GW G C C G YG+ C C C +G C C
Sbjct: 335 RDGH-ACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLC 393
Query: 425 APGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSC 465
+PG G C V+C G +G +C+ CSC+ TC PV G+C
Sbjct: 394 SPGVHGPHCNVTCPPGLHGADCAQACSCHE-DTCDPVTGAC 433
Score = 263 bits (672), Expect = 6e-70
Identities = 131/385 (34%), Positives = 175/385 (45%), Gaps = 52/385 (13%)
Query: 364 CDADNTISCHPVT---GACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
C+ ++T S + V G C C+ G+ G +C+ CP ++G C+ C+C C +TG
Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
CTC A +G C C C +G TC P G+C C+ GW
Sbjct: 140 QCTCH-------------ARRWGARCEHACQCQHG-TCHPRSGACRCEPGW--------- 176
Query: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE----------------LPCP 524
WG C +C C+ + C P G+C C GW G +C C
Sbjct: 177 ----WGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCR 232
Query: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCS-CEN 583
+ TFG C +C C C PV G C C G+ G C CP G +G C C C+
Sbjct: 233 ERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKG 291
Query: 584 GGSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC-EC 641
C+ +G C C PG+ G C + C GFYG GC+ CP C C+H++G C C
Sbjct: 292 QQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC-RDGHACNHVTGKCTRC 350
Query: 642 LPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGF 701
G+ G C C+ G +G+DCA +C+ +G C G C C PG G C+ CPPG
Sbjct: 351 NAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGL 410
Query: 702 WGPACFHACSCHNGASCSAEDGACH 726
G C ACSCH +C GACH
Sbjct: 411 HGADCAQACSCHED-TCDPVTGACH 434
Score = 252 bits (643), Expect = 1e-66
Identities = 150/463 (32%), Positives = 205/463 (44%), Gaps = 83/463 (17%)
Query: 466 TCKEGW--QGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPC 523
TC GW QG +C + C + TC+ C G C C G+ G C+ C
Sbjct: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 524 PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
P +G +C E C C C+ VTG C TC RWG C +C C++
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQC-------------TCHARRWGARCEHACQCQH 160
Query: 584 GGSCSPEDGSCECAPGFRGPLCQR-----------------ICPPGFYGHGCAQPCPLCV 626
G +C P G+C C PG+ G C +C G++G C C
Sbjct: 161 G-TCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCAC-- 217
Query: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFP 686
+S PC SG C+C GA C++ C C + G C P+DG+C C P
Sbjct: 218 -NSSPCEQQSGRCQCRERTFGARCDRYC-------QCFR-------GRCHPVDGTCACEP 262
Query: 687 GWIGKDCSQACPPGFWGPACFHACS-CHNGASCSAEDGAC-HCTPGWTGLFCTQRCPAAF 744
G+ GK C + CP GF+G C C C C+ +G C C PGW G C Q C F
Sbjct: 263 GYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGF 322
Query: 745 FGKDCGRVCQ-CQNGASCDHISGKCT-CRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNS 802
+G+ C C C++G +C+H++GKCT C G+ G CE +C+ GT+G C +C +
Sbjct: 323 YGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSG 382
Query: 803 TCDHVTGTCYCSPGFKGIRCD-------------QAALMMEE-LNPYTKISPALGAERHS 848
CD +G C CSPG G C+ QA E+ +P T +R
Sbjct: 383 HCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHEDTCDPVTGACHLETNQRKG 442
Query: 849 V-GAVTGIMLLLFLIVVLLGLFAWHR-----RRQKEKGRDLAP 885
V GA ++LL+ L++ LLG R RR+ GR AP
Sbjct: 443 VMGAGALLVLLVCLLLSLLGCCCACRGKDPTRRELSLGRKKAP 485
Score = 196 bits (497), Expect = 1e-49
Identities = 102/300 (34%), Positives = 131/300 (43%), Gaps = 53/300 (17%)
Query: 87 QCCPGYYESGDFCIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGC------------ 133
QC G C C +C HG C C CEPGW G C+S C
Sbjct: 140 QCTCHARRWGARCEHAC--QCQHGTCHPRSGACRCEPGWWGAQCASACYCSATSRCDPQT 197
Query: 134 -----DSDHWGPHCSNRCQCQNGAL----------------------------CNPITGA 160
+ WG C+N+C C + C+P+ G
Sbjct: 198 GACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGRCHPVDGT 257
Query: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPC-QCRHGASCDPRAGECL-CAPGYTGVYCEEL 218
C C G+RG C E C G +G GC+ C QC+ C G CL C PG+ G C++
Sbjct: 258 CACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQP 317
Query: 219 CPPGSHGAHCELRCP-CQNGGTCHHITGECA-CPPGWTGAVCAQPCPPGTFGQNCSQDCP 276
C G +G C RCP C++G C+H+TG+C C GW G C C GT+G++C+ C
Sbjct: 318 CATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCA 377
Query: 277 CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECE 336
G CD +G+C C+ G G C CP G G C+Q C CH C P TGAC E
Sbjct: 378 DCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGACHLE 436
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 278 bits (710), Expect = 3e-74
Identities = 267/952 (28%), Positives = 345/952 (36%), Gaps = 309/952 (32%)
Query: 89 CPGYYESGDF------CIPLCTEECVH-GRCVSPDT---CHCEPGWGGPDCSSGCDSDHW 138
CP Y+ D C + C H G+CV+ D C C G+ GP C + H
Sbjct: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS 462
Query: 139 GPHCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEE---------------------- 174
P CQN A C G C+C GF+G CE
Sbjct: 463 DP-------CQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNR 515
Query: 175 ---LCAPGTHGKGCQLPCQ------CRHGASC--DPRAGECLCAPGYTGVYCEE---LCP 220
LC PG G CQ+ C +GA C P EC CA G+TGV CEE C
Sbjct: 516 FQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD 575
Query: 221 PGSHGAHCELRCPCQNGGTCHHITG-ECACPPGWTGAVCAQP------------------ 261
P PC +G I C C PG+ GA+C+
Sbjct: 576 PD----------PCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDL 625
Query: 262 -------CPPGTFGQNCS---QDC---PCHHGGQCDHVTG-QCHCTAGYMGDRCQEECPF 307
C PGT G NC DC PC HG D + C C+ G+ G RC +
Sbjct: 626 VNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDID- 684
Query: 308 GSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
+C+ + C G C G G RC +CPEG H P C +
Sbjct: 685 -----ECASN-PCRKGATCI---------NGVNGFRC---ICPEGPHHPSCY----SQVN 722
Query: 368 NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ------LPCTCQNGADCHSITGG 421
+S + G CT G SG+ C C G+ G C+ L CQNG C ++ G
Sbjct: 723 ECLSNPCIHGNCT--GGLSGYKC--LCDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNG 778
Query: 422 --CTCAPGFMGEVCAVS-------------------------CAAGTYGPNCSSI---CS 451
CTC GF G C V+ C G NC ++ CS
Sbjct: 779 YRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCS 838
Query: 452 ---CNNGGTCSPVDG----SCTCKEGWQGLDCTL-------------------------P 479
C N C +C C GWQG CT+
Sbjct: 839 PNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCE 898
Query: 480 CPSGTWGLNCNESC------TCANGAACSPIDG----SCSCTPGWLGDTCEL-------- 521
CP G G++C E C NG +C +DG SC C PG+ GD C+
Sbjct: 899 CPPGFSGMDCEEDIDDCLANPCQNGGSC--MDGVNTFSCLCLPGFTGDKCQTDMNECLSE 956
Query: 522 PCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSC 581
PC +G CS++ + + C C AG+ G+ C++ N SC
Sbjct: 957 PCKNGG---TCSDYVN----------SYTCKCQAGFDGVHCENNI-------NECTESSC 996
Query: 582 ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICEC 641
NGG+C S C +CP GF G C C SS PC + C
Sbjct: 997 FNGGTCVDGINSFSC-----------LCPVGFTGSFCLHEINEC--SSHPCLNEG---TC 1040
Query: 642 LPGFSGALCNQVCAGGYFGQDC---AQLCS---CANNGTC--SPIDGSCQCFPGWIGKDC 693
+ G C+ C GY G++C LCS C N GTC + C C GW G C
Sbjct: 1041 VDGLGTYRCS--CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYC 1098
Query: 694 -----SQACPPGFWGPACFHACSCHNGASCSA-EDGACHCTPGWTGLFCTQRCPAAFFGK 747
S G H C H+G +A C C G+TG +C ++
Sbjct: 1099 DVPNVSCDIAASRRGVLVEHLCQ-HSGVCINAGNTHYCQCPLGYTGSYCEEQL------D 1151
Query: 748 DCGRVCQCQNGASC-DHISG-KCTCRTGFTGQHCEQR----------------------- 782
+C CQ+GA+C D I G +C C G+ G +CE
Sbjct: 1152 ECAS-NPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFK 1210
Query: 783 --CAPGTFGYGCQQLCE-------CMNNSTC-DHVTG-TCYCSPGFKGIRCD 823
C PGT G C++ + C+N C D + G +C C PGF G RC+
Sbjct: 1211 CSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
Score = 273 bits (697), Expect = 8e-73
Identities = 271/990 (27%), Positives = 351/990 (35%), Gaps = 312/990 (31%)
Query: 87 QCCPGYYESGDFCIPLCTEECVHGR-CVSPDTCH----------CEPGWGGPDCSSGCDS 135
+C G+ +G+ C + C R C++ TCH C+ G+ G +C
Sbjct: 91 RCASGF--TGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ----- 143
Query: 136 DHWGPHCSNRCQCQNGALCNPITG--ACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRH 193
W C + C NG+ C + +C C GF G +CE T C +P C+H
Sbjct: 144 --WTDACLSH-PCANGSTCTTVANQFSCKCLTGFTGQKCE------TDVNECDIPGHCQH 194
Query: 194 GASCD--PRAGECLCAPGYTGVYCEEL--------------------------CPPGSHG 225
G +C P + +C C G+TG YC+ L C PG G
Sbjct: 195 GGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEG 254
Query: 226 AHCELR---CP---CQNGGTCHH--ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPC 277
+ CE CP CQNGG C T C CPP WTG C + N C
Sbjct: 255 STCERNIDDCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDECLLQPNA-----C 309
Query: 278 HHGGQCDHVTG--QCHCTAGYMGDRCQEE-------------------------CPFGSF 310
+GG C + G C C G+ GD C E CP G
Sbjct: 310 QNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKA 369
Query: 311 GFQCSQHCD-------CHNGGQC--SPTTG--ACECEPGYKGPRCQERL----------- 348
G C H D CH G C +P G C C GYKG C E +
Sbjct: 370 GLLC--HLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDVDECAMANSNPC 427
Query: 349 ----------------CPEGLHGPGCTLPC------PCDADNTISCHPVTGACTCQPGWS 386
C +G GP C + PC D T C C PG+
Sbjct: 428 EHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDATCLDKIGGFTCLCMPGFK 487
Query: 387 GHHC----NES---------------------CPVGYYGDGCQL---PCT---CQNGADC 415
G HC NE CP G+ G CQ+ C+ C NGA C
Sbjct: 488 GVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKC 547
Query: 416 HSITGG--CTCAPGFMGEVCAVS-------------CAAGTYGPNC-------SSICS-- 451
G C CA GF G +C + C G C +ICS
Sbjct: 548 IDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQ 607
Query: 452 --------CNNGGTC-SPVDG-SCTCKEGWQGLDCTL--------PCPSGTW--GLNCNE 491
C N G C V+G C C+ G G++C + PC G G+N
Sbjct: 608 IDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGIN-RY 666
Query: 492 SCTCA---NGAACSPIDGSCSCTPGWLGDTC-------ELPCPDGTFGLNCSEHCD---- 537
SC C+ G C+ C+ P G TC CP+G +C +
Sbjct: 667 SCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLS 726
Query: 538 --CSHADGCDPVTGH-CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCS--PEDG 592
C H + ++G+ C C AGW GI C+ N +S C+NGG+C
Sbjct: 727 NPCIHGNCTGGLSGYKCLCDAGWVGINCEV-------DKNECLSNPCQNGGTCDNLVNGY 779
Query: 593 SCECAPGFRGPLC--------------QRICPPGFYGHGCAQPCP---------LCVHSS 629
C C GF+G C Q C G+ C P L S
Sbjct: 780 RCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSP 839
Query: 630 RPCHHISGICECLPGFSGALCNQVCAGGYFGQDCA---QLC---SCANNGTCSPIDGS-- 681
PC + + +C+ P F C +CA G+ GQ C C C N+G C GS
Sbjct: 840 NPCEN-AAVCKESPNFESYTC--LCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYM 896
Query: 682 CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASC--SAEDGACHCTPGWTGLFC--- 736
C+C PG+ G DC + P C NG SC +C C PG+TG C
Sbjct: 897 CECPPGFSGMDCEEDIDDCLANP-------CQNGGSCMDGVNTFSCLCLPGFTGDKCQTD 949
Query: 737 TQRCPAAFFGKDCGRVCQCQNGASC-DHI-SGKCTCRTGFTGQHCEQRCAPGTFGYGCQQ 794
C + C+NG +C D++ S C C+ GF G HCE T
Sbjct: 950 MNECLSE----------PCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINECTES----- 994
Query: 795 LCECMNNSTC-DHVTG-TCYCSPGFKGIRC 822
C N TC D + +C C GF G C
Sbjct: 995 --SCFNGGTCVDGINSFSCLCPVGFTGSFC 1022
Score = 261 bits (668), Expect = 2e-69
Identities = 250/884 (28%), Positives = 327/884 (36%), Gaps = 297/884 (33%)
Query: 148 CQNGALCNPI---TGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA--- 201
C N +C TG C C GF G C+ H C+ +C++G +C +A
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQ-------HRDPCE-KNRCQNGGTCVAQAMLG 86
Query: 202 -GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHI---TGECACPPGWTGAV 257
C CA G+TG C+ S C + PC NGGTCH + T EC C G+TG
Sbjct: 87 KATCRCASGFTGEDCQY-----STSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 258 C-------AQPCPPGT-----------------FGQNCSQDC-------PCHHGGQCDHV 286
C + PC G+ GQ C D C HGG C ++
Sbjct: 142 CQWTDACLSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNECDIPGHCQHGGTCLNL 201
Query: 287 TG--QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT---TGACECEPGYKG 341
G QC C G+ G C S C+ C NGG C T T C C PG++G
Sbjct: 202 PGSYQCQCPQGFTGQYCD------SLYVPCAP-SPCVNGGTCRQTGDFTFECNCLPGFEG 254
Query: 342 PRCQERL--CPEG--LHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVG 397
C+ + CP +G C D NT +C C P W+G C E
Sbjct: 255 STCERNIDDCPNHRCQNGGVCV-----DGVNTYNCR-------CPPQWTGQFCTEDV--- 299
Query: 398 YYGDGCQL-PCTCQNGADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 454
D C L P CQNG C + G GC C G+ G+ C+ + +C + SC
Sbjct: 300 ---DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENI------DDC-AFASCTP 349
Query: 455 GGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC---TCANGAAC--SPIDGS 507
G TC SC C EG GL C L +++C C GA C +P++G
Sbjct: 350 GSTCIDRVASFSCMCPEGKAGLLCHL-----------DDACISNPCHKGALCDTNPLNGQ 398
Query: 508 CSCTPGWLGDTCELPCPDGTFGLNCSEHCD---------CSHADGCDPVTG--HCCCLAG 556
CT CP G G +C+E D C HA C G HC CL G
Sbjct: 399 YICT-----------CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKG 447
Query: 557 WTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG--SCECAPGFRGPLC--------- 605
+ G RC+ N S C+N +C + G +C C PGF+G C
Sbjct: 448 YAGPRCEMDI-------NECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQS 500
Query: 606 ----------------QRICPPGFYGHGCAQPCPLCVHSSRPC-------HHISGI-CEC 641
Q +CPPGF G C C SS PC H +G C+C
Sbjct: 501 NPCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDIDDC--SSTPCLNGAKCIDHPNGYECQC 558
Query: 642 LPGFSGALCNQ------------------------VCAGGYFGQDCAQLCS------CAN 671
GF+G LC + +C GY G C+ C N
Sbjct: 559 ATGFTGVLCEENIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLN 618
Query: 672 NGTCSPIDG--SCQCFPGWIGKDC------------------------SQACPPGFWGPA 705
+G C + C C PG G +C S C PGF G
Sbjct: 619 DGRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQR 678
Query: 706 C---FHACS---CHNGA--------------------SCSAEDGAC--------HCTPGW 731
C C+ C GA SC ++ C +CT G
Sbjct: 679 CNIDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGL 738
Query: 732 TGLFCTQRCPAAFFGKDC---GRVC---QCQNGASCDHISG--KCTCRTGFTGQHCE--- 780
+G C C A + G +C C CQNG +CD++ +CTC+ GF G +C+
Sbjct: 739 SGYKCL--CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI 796
Query: 781 QRCAPGTFGYGCQQLCECMNNSTC-DHVTG-TCYCSPGFKGIRC 822
CA C+N TC D ++G TC+C + G C
Sbjct: 797 DECASN----------PCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Score = 241 bits (614), Expect = 3e-63
Identities = 248/890 (27%), Positives = 317/890 (35%), Gaps = 239/890 (26%)
Query: 90 PGYYESGDFCIPLCTEECVHGRC---VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRC 146
P Y + C+ + C+HG C +S C C+ GW G +C N C
Sbjct: 715 PSCYSQVNECL---SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVD----------KNEC 761
Query: 147 ---QCQNGALCNPITGA--CVCAAGFRGWRCE---ELCAP------GT------------ 180
CQNG C+ + C C GF+G+ C+ + CA GT
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHC 821
Query: 181 ----HGKGCQLPCQCRHGASCDPR----AGECLCAPGYTGVYCEELCPPGSHGAHCEL-- 230
GK CQ A C P A C +P + C LC PG G C +
Sbjct: 822 VLPYTGKNCQTVL-----APCSPNPCENAAVCKESPNFESYTC--LCAPGWQGQRCTIDI 874
Query: 231 -RC---PCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDC---PCHHGG 281
C PC N G CH+ G C CPPG++G C + DC PC +GG
Sbjct: 875 DECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDI----------DDCLANPCQNGG 924
Query: 282 QC-DHV-TGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEP 337
C D V T C C G+ GD+CQ + +C C NGG CS + C+C+
Sbjct: 925 SCMDGVNTFSCLCLPGFTGDKCQTDMN------ECLSE-PCKNGGTCSDYVNSYTCKCQA 977
Query: 338 GYKGPRCQERL-------------CPEGLHGPGCTLPCPCDAD------NTISCHPVTGA 378
G+ G C+ + C +G++ C P N S HP
Sbjct: 978 GFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNE 1037
Query: 379 CTCQPGWSGHHCNESCPVGYYGDGCQLPCT------CQNGADC--HSITGGCTCAPGFMG 430
TC G + C SCP+GY G CQ C+N C C C G+ G
Sbjct: 1038 GTCVDGLGTYRC--SCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAG 1095
Query: 431 EVCAV---SC--AAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTW 485
C V SC AA G +C + G C + C+ CP G
Sbjct: 1096 AYCDVPNVSCDIAASRRGVLVEHLCQ--HSGVCINAGNTHYCQ-----------CPLGYT 1142
Query: 486 GLNCNE------SCTCANGAACSPIDGS--CSCTPGWLGDTCELP--------------- 522
G C E S C +GA CS G C C PG+ G CE
Sbjct: 1143 GSYCEEQLDECASNPCQHGATCSDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTC 1202
Query: 523 ----------CPDGTFGLNCSEHCD-CSHADGC-------DPVTGHCC-CLAGWTGIRCD 563
CP GT GL C E+ D C+ C D + G+ C CL G+ G RC+
Sbjct: 1203 IDLVNHFKCSCPPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCE 1262
Query: 564 STCPPGRWGPNCSVSCSCENGGSCSP--EDGSCECAPGFRGPLCQR---ICP--PGFYGH 616
G S CS E C D C C F G C+ +CP P G
Sbjct: 1263 -----GDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGG 1317
Query: 617 GCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS 676
CA V S+ P I C C PGFSGA C C GQ C C
Sbjct: 1318 TCA------VASNMPDGFI---CRCPPGFSGARCQSSC-----GQ-----VKCRKGEQCV 1358
Query: 677 PIDGSCQCF-PGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLF 735
+CF P +DC C C H SCH +C C P ++G
Sbjct: 1359 HTASGPRCFCPS--PRDCESGCA----SSPCQHGGSCH--PQRQPPYYSCQCAPPFSGSR 1410
Query: 736 C------TQRCPAAFFGKDCG-----RVC-QCQNGASCDHISGKCTCRTGFTGQHCEQRC 783
C PA + C VC + N +C G C+ +C
Sbjct: 1411 CELYTAPPSTPPATCLSQYCADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPL 1470
Query: 784 APGTF-GYGCQQLC---ECM-NNSTCDHVTGTC----YCSPGFKGIRCDQ 824
+ C +LC EC+ +N C + TC YC+ FK CDQ
Sbjct: 1471 PCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQ 1520
Score = 169 bits (429), Expect = 1e-41
Identities = 151/501 (30%), Positives = 192/501 (38%), Gaps = 129/501 (25%)
Query: 409 CQNGADC---HSITGGCTCAPGFMGEVC--------------------------AVSCAA 439
C N C H+ TG C C GF+GE C CA+
Sbjct: 35 CVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKNRCQNGGTCVAQAMLGKATCRCAS 94
Query: 440 GTYGPNCSSICS--------CNNGGTCSPVDG---SCTCKEGWQGLDCTLPCPSGTWGLN 488
G G +C S C NGGTC + CTC+ G+ G +C W
Sbjct: 95 GFTGEDCQYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKEC-------QWTDA 147
Query: 489 CNESCTCANGAACSPIDG--SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDP 546
C S CANG+ C+ + SC C G+ G CE + C C H C
Sbjct: 148 C-LSHPCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE------CDIPGHCQHGGTCLN 200
Query: 547 VTG--HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDG---SCECAPGFR 601
+ G C C G+TG CDS P C+ S C NGG+C C C PGF
Sbjct: 201 LPGSYQCQCPQGFTGQYCDSLYVP------CAPS-PCVNGGTCRQTGDFTFECNCLPGFE 253
Query: 602 GPLCQR---ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGY 658
G C+R CP H C Q +CV + C C P ++G C +
Sbjct: 254 GSTCERNIDDCP----NHRC-QNGGVCVDGVNTYN-----CRCPPQWTGQFCTEDV---- 299
Query: 659 FGQDC-AQLCSCANNGTCSPIDG--SCQCFPGWIGKDCSQ--------ACPPGFW--GPA 705
+C Q +C N GTC+ +G C C GW G DCS+ +C PG
Sbjct: 300 --DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRV 357
Query: 706 CFHACSCHNGAS---CSAEDGACHCTPGWTGLFCTQR---------CPAAFFGKDCGR-- 751
+C C G + C +D AC P G C CP + G DC
Sbjct: 358 ASFSCMCPEGKAGLLCHLDD-ACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV 416
Query: 752 -VCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCE------CMNNSTC 804
C N C+H +GKC G HCE C G G C+ C N++TC
Sbjct: 417 DECAMANSNPCEH-AGKCVNTDG--AFHCE--CLKGYAGPRCEMDINECHSDPCQNDATC 471
Query: 805 -DHVTG-TCYCSPGFKGIRCD 823
D + G TC C PGFKG+ C+
Sbjct: 472 LDKIGGFTCLCMPGFKGVHCE 492
Score = 140 bits (352), Expect = 8e-33
Identities = 150/541 (27%), Positives = 196/541 (36%), Gaps = 150/541 (27%)
Query: 62 KCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFC---IPLCTEE-CVH-GRCV--- 113
+C+ H + GL T R C GY +G C + LC+ C + G CV
Sbjct: 1028 ECSSHPCLNEGTCVDGLGTY---RCSCPLGY--TGKNCQTLVNLCSRSPCKNKGTCVQKK 1082
Query: 114 SPDTCHCEPGWGGPDC---SSGCD--SDHWGPHCSNRCQCQNGALCNPITGACVCAAGFR 168
+ C C GW G C + CD + G + CQ + T C C G+
Sbjct: 1083 AESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYT 1142
Query: 169 GWRCEEL---CAPGTHGKGCQLPCQCRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGS 223
G CEE CA PCQ HGA+C G C C PGY GV CE
Sbjct: 1143 GSYCEEQLDECASN--------PCQ--HGATCSDFIGGYRCECVPGYQGVNCEYEVD--- 1189
Query: 224 HGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
C+ + PCQNGGTC + +C+CPPG G +C + +C++ C +GG
Sbjct: 1190 ---ECQNQ-PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENI------DDCARGPHCLNGG 1239
Query: 282 QC-DHVTG-QCHCTAGYMGDRCQ---EEC---PFGSFG-FQCSQ---------------- 316
QC D + G C C G+ G+RC+ EC P S G C Q
Sbjct: 1240 QCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSAFTGR 1299
Query: 317 HCD----------CHNGGQCS-----PTTGACECEPGYKGPRCQERL----------CPE 351
HC+ C NGG C+ P C C PG+ G RCQ C
Sbjct: 1300 HCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGEQCVH 1359
Query: 352 GLHGPGCTLPCPCDADNTI---------SCHPVTG----ACTCQPGWSGHHCN------- 391
GP C P P D ++ SCHP +C C P +SG C
Sbjct: 1360 TASGPRCFCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPS 1419
Query: 392 ---ESCPVGYYGDGCQLPCTCQNGADCHSIT---GGCTCAPGFMGEVCAVSCAAGTYGPN 445
+C Y D + C + H+ G C+ C+ Y N
Sbjct: 1420 TPPATCLSQYCADKAR-DGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINN 1478
Query: 446 -CSSICSC-----------NNGGTC------------SPVDGSCTCKE-GWQGLDCTLPC 480
C +C+ N TC + D C +E GW GLDC
Sbjct: 1479 QCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQ 1538
Query: 481 P 481
P
Sbjct: 1539 P 1539
Score = 124 bits (310), Expect = 6e-28
Identities = 118/417 (28%), Positives = 148/417 (35%), Gaps = 93/417 (22%)
Query: 437 CAAGTYGPNC-SSICSCNNGGTCSPVD---GSCTCKEGWQGLDCTL--PCPSGTWGLNCN 490
CAA + C C N G C G C C EG+ G C PC C
Sbjct: 19 CAAPAHALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQHRDPCEKN----RCQ 74
Query: 491 ESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPV--- 547
TC A +C C G+ G+ C+ C C + C +
Sbjct: 75 NGGTCVAQAMLGK--ATCRCASGFTGEDCQYSTSHP-----CFVSRPCLNGGTCHMLSRD 127
Query: 548 TGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSP--EDGSCECAPGFRGPLC 605
T C C G+TG C +W C +S C NG +C+ SC+C GF G C
Sbjct: 128 TYECTCQVGFTGKEC-------QWTDAC-LSHPCANGSTCTTVANQFSCKCLTGFTGQKC 179
Query: 606 QRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ 665
+ C + H C H G C LPG C Q G+ GQ C
Sbjct: 180 ETD----------VNECDIPGH----CQH-GGTCLNLPGSYQCQCPQ----GFTGQYCDS 220
Query: 666 L---CS---CANNGTCSPIDG---SCQCFPGWIGKDCSQA---CPPGFWGPACFHACSCH 713
L C+ C N GTC C C PG+ G C + CP C
Sbjct: 221 LYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNH----------RCQ 270
Query: 714 NGASCSAEDGA----CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--K 767
NG C DG C C P WTG FCT+ + CQNG +C + +G
Sbjct: 271 NGGVCV--DGVNTYNCRCPPQWTGQFCTEDVDECLLQPNA-----CQNGGTCANRNGGYG 323
Query: 768 CTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTC-DHVTG-TCYCSPGFKGIRC 822
C C G++G C + F C STC D V +C C G G+ C
Sbjct: 324 CVCVNGWSGDDCSENIDDCAF-------ASCTPGSTCIDRVASFSCMCPEGKAGLLC 373
Score = 106 bits (264), Expect = 1e-22
Identities = 86/297 (28%), Positives = 114/297 (38%), Gaps = 79/297 (26%)
Query: 552 CCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPED---GSCECAPGFRGPLCQRI 608
CC A ++C P C N G C G C+C GF G CQ
Sbjct: 18 CCAAPAHALQCRDGYEP------------CVNEGMCVTYHNGTGYCKCPEGFLGEYCQH- 64
Query: 609 CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS 668
PC C + G C A C CA G+ G+DC S
Sbjct: 65 ----------RDPC-----EKNRCQN-GGTCVAQAMLGKATCR--CASGFTGEDCQYSTS 106
Query: 669 --------CANNGTCSPIDGS---CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGAS 717
C N GTC + C C G+ GK+C W AC + C NG++
Sbjct: 107 HPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQ-------WTDACL-SHPCANGST 158
Query: 718 CS--AEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTG 773
C+ A +C C G+TG Q+C +C CQ+G +C ++ G +C C G
Sbjct: 159 CTTVANQFSCKCLTGFTG----QKCETDV--NECDIPGHCQHGGTCLNLPGSYQCQCPQG 212
Query: 774 FTGQHCEQR---CAPGTFGYGCQQLCECMNNSTCDHV---TGTCYCSPGFKGIRCDQ 824
FTGQ+C+ CAP C+N TC T C C PGF+G C++
Sbjct: 213 FTGQYCDSLYVPCAPSP----------CVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 272 bits (696), Expect = 1e-72
Identities = 227/713 (31%), Positives = 274/713 (38%), Gaps = 189/713 (26%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSD---HWGPHCS 143
CCP ++G + T +HG +S TC CEPGWGGP CS D++ P S
Sbjct: 125 CCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSAS 184
Query: 144 NRC--QCQNGALCNPITGACVCAAGFRGWRCEELCAPGT---HGKGCQLPCQCRHGAS-- 196
C C + C + G CVC G+ G C PG G+ Q C CR G S
Sbjct: 185 GSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGP 242
Query: 197 -CDPRA-------------GECLCAPGYTGVYC------------------EELCPPGSH 224
C R+ G C+C PGYTG C +C PG
Sbjct: 243 DCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMRSCPRGCSQRGRCENGRCVCNPGYT 302
Query: 225 GAHCELR-CP--CQNGGTCHHITGECACPPGWTGAVC-AQPCP----------------- 263
G C +R CP C G C G C C PG+TG C + CP
Sbjct: 303 GEDCGVRSCPRGCSQRGRCK--DGRCVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCW 360
Query: 264 PGTFGQNCS-QDCP--CHHGGQCDHVTGQCHCTAGYMGDRC-QEECPFGSFGFQCSQHCD 319
PG G++CS + CP C G+C+ G+C C GY GD C CP D
Sbjct: 361 PGYTGEDCSTRTCPRDCRGRGRCE--DGECICDTGYSGDDCGVRSCP-----------GD 407
Query: 320 CHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGAC 379
C+ G+C G C C PGY G C R CP G G C+ G C
Sbjct: 408 CNQRGRCE--DGRCVCWPGYTGTDCGSRACPRDCRGRG-----RCE----------NGVC 450
Query: 380 TCQPGWSGHHCN-ESCPVGYYGDG-CQL-PCTC---QNGADC-------------HSITG 420
C G+SG C SCP G G C+ C C G DC + G
Sbjct: 451 VCNAGYSGEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDG 510
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLP 479
C C PGF GE C G C G C DG C C G+ G DC T
Sbjct: 511 RCVCNPGFTGEDCGSRRCPG----------DCRGHGLCE--DGVCVCDAGYSGEDCSTRS 558
Query: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCEL-PCPDGTFGLNCSEHCDC 538
CP G C C +DG C C G+ G+ C + CP+ +CS+H C
Sbjct: 559 CPGG-----------CRGRGQC--LDGRCVCEDGYSGEDCGVRQCPN-----DCSQHGVC 600
Query: 539 SHADGCDPVTGHCCCLAGWTGIRCD-STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECA 597
G C C G+ C TCP +C G C E+G C C
Sbjct: 601 Q--------DGVCICWEGYVSEDCSIRTCP-----------SNCHGRGRC--EEGRCLCD 639
Query: 598 PGFRGPLC-QRICPPGFYGHG-CAQPCPLC--VHSSRPCHHISGICECLPGFSG--ALCN 651
PG+ GP C R+CP G G C Q LC + C PG G LC
Sbjct: 640 PGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCR 699
Query: 652 Q---VCAGGYFGQDCA-QLC--SCANNGTCSPIDGSCQCFPGWIGKDCSQACP 698
VC G+ G DCA Q C C G C DGSC C G+ G+DC + P
Sbjct: 700 AGQCVCVEGFRGPDCAIQTCPGDCRGRGECH--DGSCVCKDGYAGEDCGEEVP 750
Score = 260 bits (664), Expect = 5e-69
Identities = 218/756 (28%), Positives = 282/756 (37%), Gaps = 229/756 (30%)
Query: 215 CEELCPPGSHGA---HCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP---PGTFG 268
C C P S A ++R C G C+C PGW G C+ P P +
Sbjct: 121 CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSP 180
Query: 269 QNCSQDCP--CHHGGQCDHVTGQCHCTAGYMGDRCQ-EECPFGSFGFQCSQHCDCHNGGQ 325
+ S CP C+ G+C V G+C C GY G C CP DC G+
Sbjct: 181 PSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPG-----------DCQGRGR 227
Query: 326 CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGW 385
C G C C G+ GP C +R CP G C+ C+ G C C PG+
Sbjct: 228 C--VQGVCVCRAGFSGPDCSQRSCPRG-----CSQRGRCEG----------GRCVCDPGY 270
Query: 386 SGHHCN-ESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAV-SCAAGTYG 443
+G C SCP GC C+NG C C PG+ GE C V SC G
Sbjct: 271 TGDDCGMRSCP-----RGCSQRGRCENGR--------CVCNPGYTGEDCGVRSCPRG--- 314
Query: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC-TLPCPSGTWGLNCNESCTCANGAACS 502
C+ G C DG C C G+ G DC T CP W C G C
Sbjct: 315 --------CSQRGRCK--DGRCVCDPGYTGEDCGTRSCP---WD--------CGEGGRC- 352
Query: 503 PIDGSCSCTPGWLGDTC------------------ELPCPDGTFGLNCSEHC---DCSHA 541
+DG C C PG+ G+ C E C G G +C DC+
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQR 411
Query: 542 DGCDPVTGHCCCLAGWTGIRCDS------------------TCPPGRWGPNCSV-SC--S 580
C+ G C C G+TG C S C G G +C V SC
Sbjct: 412 GRCED--GRCVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGEDCGVRSCPGD 469
Query: 581 CENGGSCSPEDGSCECAPGFRGPLC------------------QRICPPGFYGHGC-AQP 621
C G C E G C C PG+ G C + +C PGF G C ++
Sbjct: 470 CRGRGRC--ESGRCMCWPGYTGRDCGTRACPGDCRGRGRCVDGRCVCNPGFTGEDCGSRR 527
Query: 622 CPLCVHSSRPCHHISGICECLPGFSGALCNQ------------------VCAGGYFGQDC 663
CP C G+C C G+SG C+ VC GY G+DC
Sbjct: 528 CPGDCRGHGLCE--DGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDC 585
Query: 664 A-QLC--SCANNGTCSPIDGSCQCFPGWIGKDCS-QACPPGFWGPACFHACSCHNGASCS 719
+ C C+ +G C DG C C+ G++ +DCS + CP +CH C
Sbjct: 586 GVRQCPNDCSQHGVCQ--DGVCICWEGYVSEDCSIRTCPS-----------NCHGRGRC- 631
Query: 720 AEDGACHCTPGWTGLFC-TQRCPA-----------------AFFGKDCGR----VCQCQN 757
E+G C C PG+TG C T+ CPA + G+DCG+ C
Sbjct: 632 -EEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPG 690
Query: 758 GASCDHI--SGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSP 815
G + +G+C C GF G C + PG +C C G+C C
Sbjct: 691 GCGPRELCRAGQCVCVEGFRGPDCAIQTCPG----------DCRGRGECH--DGSCVCKD 738
Query: 816 GFKGIRCDQAA--------LMMEELNPYTKISPALG 843
G+ G C + ++EE T+ +PA G
Sbjct: 739 GYAGEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPG 774
Score = 177 bits (450), Expect = 4e-44
Identities = 138/446 (30%), Positives = 167/446 (37%), Gaps = 135/446 (30%)
Query: 88 CCPGYYESGDFC-IPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSS-GCDSDHWGPHCSN 144
C GY SGD C + C +C GRC C C PG+ G DC S C D C
Sbjct: 390 CDTGY--SGDDCGVRSCPGDCNQRGRC-EDGRCVCWPGYTGTDCGSRACPRD-----CRG 441
Query: 145 RCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGEC 204
R +C+NG CVC AG+ G C PG CR C+ +G C
Sbjct: 442 RGRCENGV--------CVCNAGYSGEDCGVRSCPG----------DCRGRGRCE--SGRC 481
Query: 205 LCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQP--- 261
+C PGYTG C PG C+ G C + G C C PG+TG C
Sbjct: 482 MCWPGYTGRDCGTRACPGD----------CRGRGRC--VDGRCVCNPGFTGEDCGSRRCP 529
Query: 262 ---------------CPPGTFGQNCS-QDCP--CHHGGQCDHVTGQCHCTAGYMGDRCQ- 302
C G G++CS + CP C GQC + G+C C GY G+ C
Sbjct: 530 GDCRGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQC--LDGRCVCEDGYSGEDCGV 587
Query: 303 EECPFGSFGFQCSQH-------------------------CDCHNGGQCSPTTGACECEP 337
+CP CSQH +CH G+C G C C+P
Sbjct: 588 RQCPN-----DCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE--GRCLCDP 640
Query: 338 GYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC-NESCPV 396
GY GP C R+CP G G V G C C G+ G C E P
Sbjct: 641 GYTGPTCATRMCPADCRGRG---------------RCVQGVCLCHVGYGGEDCGQEEPPA 685
Query: 397 GYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGG 456
GC C+ G C C GF G CA+ G C G
Sbjct: 686 SACPGGCGPRELCR--------AGQCVCVEGFRGPDCAIQTCPG----------DCRGRG 727
Query: 457 TCSPVDGSCTCKEGWQGLDCTLPCPS 482
C DGSC CK+G+ G DC P+
Sbjct: 728 ECH--DGSCVCKDGYAGEDCGEEVPT 751
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 232 bits (591), Expect = 2e-60
Identities = 177/580 (30%), Positives = 232/580 (40%), Gaps = 177/580 (30%)
Query: 258 CAQPCPPGTFGQNCSQ-DCP--CHHGGQCDHVTGQCHCTAGYMGDRC-QEECPFGSFGFQ 313
C C PG G NCS+ +CP CH G+C + GQC C G+ G+ C Q CP
Sbjct: 172 CGCVCEPGWKGPNCSEPECPGNCHLRGRC--IDGQCICDDGFTGEDCSQLACP------- 222
Query: 314 CSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCH 373
DC++ G+C G C C GY G C +C P PC ++ +C
Sbjct: 223 ----SDCNDQGKC--VNGVCICFEGYAGADCSREIC-----------PVPCSEEHG-TC- 263
Query: 374 PVTGACTCQPGWSGHHCNES------------------CPVGYYGDGCQ---LPCTCQNG 412
V G C C G++G CN+ C G+ G+ C P C +
Sbjct: 264 -VDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDR 322
Query: 413 ADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQ 472
C I G C C GF GE C P C +C+ G C +G C C EG+
Sbjct: 323 GRC--INGTCYCEEGFTGEDCG--------KPTCPH--ACHTQGRCE--EGQCVCDEGFA 368
Query: 473 GLDCT-LPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCPDGTFGL 530
G+DC+ CP+ C N C +DG C C G+ G C EL CP+G
Sbjct: 369 GVDCSEKRCPA-----------DCHNRGRC--VDGRCECDDGFTGADCGELKCPNG---- 411
Query: 531 NCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDS-TCPPGRWGPNCSVSCSCENGGSCSP 589
CS H C V G C C G+TG C CP C + G C
Sbjct: 412 -CSGHGRC--------VNGQCVCDEGYTGEDCSQLRCPN-----------DCHSRGRC-- 449
Query: 590 EDGSCECAPGFRGPLCQRI-CPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGA 648
+G C C GF+G C + CP + HG ++G+C C G++G
Sbjct: 450 VEGKCVCEQGFKGYDCSDMSCPNDCHQHG---------------RCVNGMCVCDDGYTGE 494
Query: 649 LCNQ------------------VCAGGYFGQDCAQLC---SCANNGTCSPIDGSCQCFPG 687
C VC G+ G DCA+L C G C ++G C C G
Sbjct: 495 DCRDRQCPRDCSNRGLCVDGQCVCEDGFTGPDCAELSCPNDCHGQGRC--VNGQCVCHEG 552
Query: 688 WIGKDC-SQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQR-CPAAFF 745
++GKDC Q CP CH C DG C C G+TGL C Q CP+
Sbjct: 553 FMGKDCKEQRCP-----------SDCHGQGRC--VDGQCICHEGFTGLDCGQHSCPS--- 596
Query: 746 GKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAP 785
DC + QC +SG+C C G++G+ C + P
Sbjct: 597 --DCNNLGQC--------VSGRCICNEGYSGEDCSEVSPP 626
Score = 218 bits (555), Expect = 2e-56
Identities = 173/564 (30%), Positives = 213/564 (37%), Gaps = 181/564 (32%)
Query: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCA 177
C CEPGW GP+CS P C C + I G C+C GF G C +L
Sbjct: 174 CVCEPGWKGPNCSE--------PECPGNCHLRGRC----IDGQCICDDGFTGEDCSQLAC 221
Query: 178 P---GTHGKG--------------------CQLPCQCRHGASCDPRAGECLCAPGYTGVY 214
P GK C +PC HG D G C+C G+ G
Sbjct: 222 PSDCNDQGKCVNGVCICFEGYAGADCSREICPVPCSEEHGTCVD---GLCVCHDGFAGDD 278
Query: 215 C------------------EELCPPGSHGAHC-ELRCP--CQNGGTCHHITGECACPPGW 253
C E +C G G C EL CP C + G C I G C C G+
Sbjct: 279 CNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSELICPNDCFDRGRC--INGTCYCEEGF 336
Query: 254 TGAVCAQP-CPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEE-CPFGSFG 311
TG C +P CP CH G+C+ GQC C G+ G C E+ CP
Sbjct: 337 TGEDCGKPTCPHA-----------CHTQGRCEE--GQCVCDEGFAGVDCSEKRCP----- 378
Query: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL--PCPCDADNT 369
DCHN G+C G CEC+ G+ G C E CP G G G + C CD T
Sbjct: 379 ------ADCHNRGRC--VDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYT 430
Query: 370 ----------ISCHP----VTGACTCQPGWSGHHCNE-SCPVGYYGDGCQLPCTCQNGAD 414
CH V G C C+ G+ G+ C++ SCP D
Sbjct: 431 GEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCSDMSCP-----------------ND 473
Query: 415 CHS----ITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEG 470
CH + G C C G+ GE C C C+N G C VDG C C++G
Sbjct: 474 CHQHGRCVNGMCVCDDGYTGEDCR--------DRQCPR--DCSNRGLC--VDGQCVCEDG 521
Query: 471 WQGLDCT-LPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC-ELPCPDGTF 528
+ G DC L CP+ +C+ C N G C C G++G C E CP
Sbjct: 522 FTGPDCAELSCPN-----DCHGQGRCVN--------GQCVCHEGFMGKDCKEQRCPS--- 565
Query: 529 GLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRC-DSTCPPGRWGPNCSVSCSCENGGSC 587
DC C V G C C G+TG+ C +CP C N G C
Sbjct: 566 --------DCHGQGRC--VDGQCICHEGFTGLDCGQHSCP-----------SDCNNLGQC 604
Query: 588 SPEDGSCECAPGFRGPLCQRICPP 611
G C C G+ G C + PP
Sbjct: 605 --VSGRCICNEGYSGEDCSEVSPP 626
Score = 190 bits (483), Expect = 5e-48
Identities = 153/484 (31%), Positives = 188/484 (38%), Gaps = 143/484 (29%)
Query: 88 CCPGYYE---SGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
C GY S + C C+EE HG CV C C G+ G DC+ P C N
Sbjct: 238 CFEGYAGADCSREICPVPCSEE--HGTCVD-GLCVCHDGFAGDDCNK--------PLCLN 286
Query: 145 RCQCQNGALCNPITGACVCAAGFRGWRCEEL------------------CAPGTHGKGCQ 186
C N C + CVC GF G C EL C G G+ C
Sbjct: 287 NCY--NRGRC--VENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCEEGFTGEDCG 342
Query: 187 LPCQCRHGASCDPRA--GECLCAPGYTGVYC-EELCPPGSH-----------------GA 226
P C H R G+C+C G+ GV C E+ CP H GA
Sbjct: 343 KPT-CPHACHTQGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRCVDGRCECDDGFTGA 401
Query: 227 HC-ELRCP--CQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC 283
C EL+CP C G C + G+C C G+TG C+Q C D CH G+C
Sbjct: 402 DCGELKCPNGCSGHGRC--VNGQCVCDEGYTGEDCSQ--------LRCPND--CHSRGRC 449
Query: 284 DHVTGQCHCTAGYMGDRCQE-ECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGP 342
V G+C C G+ G C + CP DCH G+C G C C+ GY G
Sbjct: 450 --VEGKCVCEQGFKGYDCSDMSCP-----------NDCHQHGRC--VNGMCVCDDGYTGE 494
Query: 343 RCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNE-SCPVGYYGD 401
C++R CP D N C V G C C+ G++G C E SCP +G
Sbjct: 495 DCRDRQCPR-------------DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHGQ 539
Query: 402 GCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPV 461
G + G C C GFMG+ C C S C+ G C V
Sbjct: 540 G-------------RCVNGQCVCHEGFMGKDCKEQ--------RCPS--DCHGQGRC--V 574
Query: 462 DGSCTCKEGWQGLDC-TLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE 520
DG C C EG+ GLDC CPS +CN C + G C C G+ G+ C
Sbjct: 575 DGQCICHEGFTGLDCGQHSCPS-----DCNNLGQC--------VSGRCICNEGYSGEDCS 621
Query: 521 LPCP 524
P
Sbjct: 622 EVSP 625
Score = 133 bits (335), Expect = 8e-31
Identities = 109/350 (31%), Positives = 137/350 (39%), Gaps = 105/350 (30%)
Query: 88 CCPGYYESGDFCIPL-CTEECV-HGRCVSPDTCHCEPGWGGPDCSSG------------- 132
C G+ +G+ C L C +C GRC++ TC+CE G+ G DC
Sbjct: 301 CDEGF--TGEDCSELICPNDCFDRGRCIN-GTCYCEEGFTGEDCGKPTCPHACHTQGRCE 357
Query: 133 -----CDSDHWGPHCSN-RC--QCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKG 184
CD G CS RC C N C + G C C GF G C EL P G
Sbjct: 358 EGQCVCDEGFAGVDCSEKRCPADCHNRGRC--VDGRCECDDGFTGADCGELKCPN----G 411
Query: 185 CQLPCQCRHGASCDPRAGECLCAPGYTGVYCEEL-CPPGSH--GAHCELRCPCQNG---- 237
C +C +G +C+C GYTG C +L CP H G E +C C+ G
Sbjct: 412 CSGHGRCVNG--------QCVCDEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGY 463
Query: 238 --------GTCHH----ITGECACPPGWTGAVCAQP------------------CPPGTF 267
CH + G C C G+TG C C G
Sbjct: 464 DCSDMSCPNDCHQHGRCVNGMCVCDDGYTGEDCRDRQCPRDCSNRGLCVDGQCVCEDGFT 523
Query: 268 GQNCSQ-DCP--CHHGGQCDHVTGQCHCTAGYMGDRCQEE------------------CP 306
G +C++ CP CH G+C V GQC C G+MG C+E+ C
Sbjct: 524 GPDCAELSCPNDCHGQGRC--VNGQCVCHEGFMGKDCKEQRCPSDCHGQGRCVDGQCICH 581
Query: 307 FGSFGFQCSQHC---DCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGL 353
G G C QH DC+N GQC +G C C GY G C E P+ L
Sbjct: 582 EGFTGLDCGQHSCPSDCNNLGQC--VSGRCICNEGYSGEDCSEVSPPKDL 629
Score = 77.4 bits (189), Expect = 6e-14
Identities = 54/197 (27%), Positives = 72/197 (36%), Gaps = 59/197 (29%)
Query: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQ------------------ACPPGFWGPACFH-A 709
C+ G S C C PGW G +CS+ C GF G C A
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHLRGRCIDGQCICDDGFTGEDCSQLA 220
Query: 710 C--SCHNGASCSAEDGACHCTPGWTGLFCTQR-------------------CPAAFFGKD 748
C C++ C +G C C G+ G C++ C F G D
Sbjct: 221 CPSDCNDQGKC--VNGVCICFEGYAGADCSREICPVPCSEEHGTCVDGLCVCHDGFAGDD 278
Query: 749 CGR-VC--QCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCD 805
C + +C C N C + +C C GFTG+ C + P +C + C
Sbjct: 279 CNKPLCLNNCYNRGRC--VENECVCDEGFTGEDCSELICPN----------DCFDRGRC- 325
Query: 806 HVTGTCYCSPGFKGIRC 822
+ GTCYC GF G C
Sbjct: 326 -INGTCYCEEGFTGEDC 341
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 224 bits (570), Expect = 4e-58
Identities = 223/809 (27%), Positives = 289/809 (35%), Gaps = 211/809 (26%)
Query: 97 DFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCN- 155
D CIP CVHG C P C CE WGG C + +C C NG C+
Sbjct: 263 DKCIP--HPGCVHGICNEPWQCLCETNWGGQLCDKDLN------YCGTHQPCLNGGTCSN 314
Query: 156 --PITGACVCAAGFRGWRC---EELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGY 210
P C C G+ G C E C PC R EC C+PG+
Sbjct: 315 TGPDKYQCSCPEGYSGPNCEIAEHACLSD--------PCHNRGSCKETSLGFECECSPGW 366
Query: 211 TGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVC------- 258
TG C + C P + C +GGTC + +C CPP WTG C
Sbjct: 367 TGPTCSTNIDDCSPNN----------CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANEC 416
Query: 259 -AQPCP-----------------PGTFGQNCS---QDC--PCHHGGQC-DHVTG-QCHCT 293
A+PC PG GQNC DC C + C D V G +C C
Sbjct: 417 EAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICP 476
Query: 294 AGYMGDRCQ---EECPFGSF--GFQCSQ-----HCDC---HNGGQCSPTTGACECEPGYK 340
GY GD C+ +EC G C C C +G C CE P
Sbjct: 477 PGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQN 536
Query: 341 GPRCQERL------CPEGLHGPGC--------TLPCPCDADNTIS--------------- 371
G +C R CPE G C T PC T++
Sbjct: 537 GAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISS 596
Query: 372 --------CHPVTG---ACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
C +G C C G++G +C+E+ + C+ TC +G + +
Sbjct: 597 NVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIN-DCESNPCRNGGTCIDGVNSYK--- 652
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPV--DGSCTCKEGWQGLDCTL 478
C C+ G+ G C + + P C+NGGTC + D C CK GW+G C
Sbjct: 653 -CICSDGWEGAYCETNINDCSQNP-------CHNGGTCRDLVNDFYCDCKNGWKGKTC-- 702
Query: 479 PCPSGTWGLNCNESCTCANGAACSPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHC 536
+ C+E+ TC NG C + C C GW G TC + C
Sbjct: 703 ----HSRDSQCDEA-TCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLPNPC---- 753
Query: 537 DCSHADGCDPVTGH---CCCLAGWTGIRC---DSTCPPGRWGPNCSVSCSCENGGSCSPE 590
H G V G C C GW G C + C P C N G+C
Sbjct: 754 ---HNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPH----------PCYNSGTCVDG 800
Query: 591 DG--SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI-CECLPGFSG 647
D CECAPGF GP C+ Q P C + I+G C C PG SG
Sbjct: 801 DNWYRCECAPGFAGPDCR-------ININECQSSP-CAFGATCVDEINGYRCVCPPGHSG 852
Query: 648 ALCNQVCAGGYFGQDCAQLCSCANNGTCSPID-GSCQCFPGWIGKDCSQACPPGFWGPAC 706
A C +V G+ C + S +G D +CQC G I AC + GP
Sbjct: 853 AKCQEVS-----GRPCITMGSVIPDGAKWDDDCNTCQCLNGRI------ACSKVWCGP-- 899
Query: 707 FHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISG 766
C H G S C G + C F C V +C++ +S +
Sbjct: 900 -RPCLLHKGHS--------ECPSGQS---CIPILDDQCFVHPCTGVGECRS-SSLQPVKT 946
Query: 767 KCTCRTGFTGQHCEQRCAPGTFGYGCQQL 795
KCT + + + CA TF + + +
Sbjct: 947 KCT-----SDSYYQDNCANITFTFNKEMM 970
Score = 191 bits (484), Expect = 4e-48
Identities = 199/756 (26%), Positives = 255/756 (33%), Gaps = 218/756 (28%)
Query: 206 CAPGYTGVYCEELCPPGS----HGAHCELRCPCQNGGTCHHITGECACPPGWTG-----A 256
C Y G C + C P H A C+ QNG C GW G A
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYA-CD-----QNGNK--------TCMEGWMGPECNRA 232
Query: 257 VCAQPCPPGTFGQNCSQDCPCHHGGQ---CD-------------HVTGQCHCTAGYMGDR 300
+C Q C P DC C +G Q CD + QC C + G
Sbjct: 233 ICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQL 292
Query: 301 CQEECPFGSFGFQCSQHCDCHNGGQCS---PTTGACECEPGYKGPRCQ--ERLCPEGLHG 355
C ++ + C H C NGG CS P C C GY GP C+ E C
Sbjct: 293 CDKDLNY------CGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHAC------ 340
Query: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADC 415
L PC + + C C PGW+G C+ + D C P C +G C
Sbjct: 341 ----LSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNI------DDCS-PNNCSHGGTC 389
Query: 416 HSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGW 471
+ G C C P + G+ C + N C N +C + S C C GW
Sbjct: 390 QDLVNGFKCVCPPQWTGKTCQLDA-------NECEAKPCVNAKSCKNLIASYYCDCLPGW 442
Query: 472 QGLDCTLPCPSGTWGLNCNESC-TCANGAACSPIDGS--CSCTPGWLGDTCEL------- 521
G +C +N N+ C N A+C + C C PG+ GD CE
Sbjct: 443 MGQNC---------DININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECAS 493
Query: 522 -PCPDGTFGLNCSEHCDCSHADG-----CDPVTGHCCCLAGWTGIRCDS-------TCPP 568
PC +G N C G C +C G +C + CP
Sbjct: 494 NPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPE 553
Query: 569 GRWGPNCS------VSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPP----------- 611
G NCS + CE SC+ S + G R + +C P
Sbjct: 554 DYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVR-YISSNVCGPHGKCKSQSGGK 612
Query: 612 -------GFYGHGCAQPCPLCVHSSRPCHH----ISGI----CECLPGFSGALCNQVCAG 656
GF G C + C S PC + I G+ C C G+ GA C
Sbjct: 613 FTCDCNKGFTGTYCHENINDC--ESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNI-- 668
Query: 657 GYFGQDCAQLCSCANNGTCSPI--DGSCQCFPGWIGKDCSQ------------------- 695
DC+Q C N GTC + D C C GW GK C
Sbjct: 669 ----NDCSQ-NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE 723
Query: 696 ------ACPPGFWGPACFHACS-------CHNGASC--SAEDGACHCTPGWTGLFCTQRC 740
CP G+ G C A + CHNG +C + E C C GW G C Q
Sbjct: 724 GDAFKCMCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNT 783
Query: 741 PAAFFGKDCGRVCQCQNGASCDHISG----KCTCRTGFTGQHC-----EQRCAPGTFGYG 791
DC C N +C + G +C C GF G C E + +P FG
Sbjct: 784 ------NDCS-PHPCYNSGTC--VDGDNWYRCECAPGFAGPDCRININECQSSPCAFGAT 834
Query: 792 CQQLCECMNNSTCDHVTG-TCYCSPGFKGIRCDQAA 826
C D + G C C PG G +C + +
Sbjct: 835 C-----------VDEINGYRCVCPPGHSGAKCQEVS 859
Score = 159 bits (402), Expect = 1e-38
Identities = 185/672 (27%), Positives = 230/672 (34%), Gaps = 207/672 (30%)
Query: 54 CTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCV 113
C D++N FKC CP + +G C L EC CV
Sbjct: 389 CQDLVNGFKCV------------------------CPPQW-TGKTC-QLDANECEAKPCV 422
Query: 114 SPDT---------CHCEPGWGGPDCSSGCDSDHWGPHCSNRC--QCQNGALCNPITGA-- 160
+ + C C PGW G +C N C QCQN A C +
Sbjct: 423 NAKSCKNLIASYYCDCLPGWMGQNCDINI----------NDCLGQCQNDASCRDLVNGYR 472
Query: 161 CVCAAGFRGWRCEE-------------------------LCAPGTHGKGCQL------PC 189
C+C G+ G CE LC G G CQL P
Sbjct: 473 CICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN 532
Query: 190 QCRHGASCDPRAGE--CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC------- 240
C++GA C RA + C C Y G C L HC PC+ +C
Sbjct: 533 PCQNGAQCYNRASDYFCKCPEDYEGKNCSHL------KDHCR-TTPCEVIDSCTVAMASN 585
Query: 241 ------HHITGECACPPG----WTGAVCAQPCPPGTFGQNCSQ---DC---PCHHGGQC- 283
+I+ P G +G C G G C + DC PC +GG C
Sbjct: 586 DTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCI 645
Query: 284 DHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTG--ACECEPGYK 340
D V +C C+ G+ G C+ CSQ+ CHNGG C C+C+ G+K
Sbjct: 646 DGVNSYKCICSDGWEGAYCETNIN------DCSQN-PCHNGGTCRDLVNDFYCDCKNGWK 698
Query: 341 GPRCQER--LCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC----NESC 394
G C R C E G T C + D C C GW G C N SC
Sbjct: 699 GKTCHSRDSQCDEATCNNGGT--CYDEGD--------AFKCMCPGGWEGTTCNIARNSSC 748
Query: 395 PVGYYGDGCQLPCTCQNGADC--HSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSC 452
LP C NG C + + C C G+ G +CA N S C
Sbjct: 749 ----------LPNPCHNGGTCVVNGESFTCVCKEGWEGPICA-------QNTNDCSPHPC 791
Query: 453 NNGGTCSPVDGS----CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC-SPIDG- 506
N GTC VDG C C G+ G DC + +N +S CA GA C I+G
Sbjct: 792 YNSGTC--VDGDNWYRCECAPGFAGPDCRI-------NINECQSSPCAFGATCVDEINGY 842
Query: 507 SCSCTPGWLGDTCE----LPC-------PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLA 555
C C PG G C+ PC PDG + C C + G C
Sbjct: 843 RCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDCNTCQC--------LNGRIACSK 894
Query: 556 GWTGIR-C-----DSTCPPGRWGPNCSVSCSCENGGSC--SPEDGSCECAPGFRGPLCQR 607
W G R C S CP G+ SC C P G EC P+ +
Sbjct: 895 VWCGPRPCLLHKGHSECPSGQ-------SCIPILDDQCFVHPCTGVGECRSSSLQPVKTK 947
Query: 608 ICPPGFYGHGCA 619
+Y CA
Sbjct: 948 CTSDSYYQDNCA 959
Score = 149 bits (375), Expect = 2e-35
Identities = 121/406 (29%), Positives = 156/406 (38%), Gaps = 86/406 (21%)
Query: 435 VSCAAGTYGPNCSSICSCNN---GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNE 491
V+C YG C+ C + G +G+ TC EGW G +C C +
Sbjct: 185 VTCDDYYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGPECNRAI--------CRQ 236
Query: 492 SCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHC 551
C+ +G+ P G C C GW G C+ C H C H +P C
Sbjct: 237 GCSPKHGSCKLP--GDCRCQYGWQGLYCD----------KCIPHPGCVHGICNEP--WQC 282
Query: 552 CCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCS---PEDGSCECAPGFRGPLCQRI 608
C W G CD C C NGG+CS P+ C C G+ GP C+
Sbjct: 283 LCETNWGGQLCDKDL------NYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE-- 334
Query: 609 CPPGFYGHGC-AQPCPLCVHSSRPCHHIS-GI-CECLPGFSGALCNQVCAGGYFGQDCAQ 665
H C + PC H+ C S G CEC PG++G C+ DC+
Sbjct: 335 ----IAEHACLSDPC----HNRGSCKETSLGFECECSPGWTGPTCSTNI------DDCSP 380
Query: 666 LCSCANNGTCSPIDG--SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDG 723
+C++ GTC + C C P W GK C Q C +A SC N
Sbjct: 381 -NNCSHGGTCQDLVNGFKCVCPPQWTGKTC-QLDANECEAKPCVNAKSCKN----LIASY 434
Query: 724 ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC-DHISG-KCTCRTGFTGQHCEQ 781
C C PGW G C DC + QCQN ASC D ++G +C C G+ G HCE+
Sbjct: 435 YCDCLPGWMGQNCDINI------NDC--LGQCQNDASCRDLVNGYRCICPPGYAGDHCER 486
Query: 782 ---RCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRC 822
CA C+N C + C C GF G C
Sbjct: 487 DIDECASN----------PCLNGGHCQNEINRFQCLCPTGFSGNLC 522
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 218 bits (554), Expect = 3e-56
Identities = 260/952 (27%), Positives = 333/952 (34%), Gaps = 267/952 (28%)
Query: 97 DFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC-- 154
D C+P CVHG CV P C+CE WGG C + +C + C NG C
Sbjct: 274 DECVPY--PGCVHGSCVEPWQCNCETNWGGLLCDKDLN------YCGSHHPCTNGGTCIN 325
Query: 155 -NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCD--PRAGECLCAPGYT 211
P C C G+ G CE+ T C +G SC P EC C G++
Sbjct: 326 AEPDQYRCTCPDGYSGRNCEKAEHACTSN-------PCANGGSCHEVPSGFECHCPSGWS 378
Query: 212 GVYCE---ELCPPGSHGAHCELRCPCQNGGTC-HHITG-ECACPPGWTGAVC-------- 258
G C + C PC GGTC + G EC CP W GA C
Sbjct: 379 GPTCALDIDECASN----------PCAAGGTCVDQVDGFECICPEQWVGATCQLDANECE 428
Query: 259 AQP-----------------CPPGTFGQNCS---QDC--PCHHGGQC-DHVTG-QCHCTA 294
+P C PG G NC DC C HGG C D V G QC C
Sbjct: 429 GKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPR 488
Query: 295 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQ--ERLCP 350
G+ G C+ E +C+ CH+GG C C C G+ GP C+ LC
Sbjct: 489 GFGGRHCELERD------ECAS-SPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCE 541
Query: 351 EGLHGPGCTLPCPCDADNTISCHPVTG--ACTCQPGWSGHHCN---ESCPVGYYG--DGC 403
P PC N C+ + G C C + G +C+ E CP G DGC
Sbjct: 542 ----------PSPC--RNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGC 589
Query: 404 ------QLPCTCQNG-----ADCHSITGG---CTCAPGFMGEVCAVSCAAGTYGPNCSSI 449
+P T +G C S GG C C GF G C + P
Sbjct: 590 GSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP----- 644
Query: 450 CSCNNGGTC-SPVDG-SCTCKEGWQGLDC------TLP-------------------CPS 482
C NGGTC VD C C GW+G C LP C
Sbjct: 645 --CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDD 702
Query: 483 GTWGLNCN------ESCTCANGAAC--SPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
G G C+ ++ TC+NG C S C+C PGW G TC + C
Sbjct: 703 GWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVN 762
Query: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRC---DSTCPPGRWGPNCSVSCSCENGGSCSPED 591
C + + C C GW G C + C P C NGG C D
Sbjct: 763 GGTCVGSG----ASFSCICRDGWEGRTCTHNTNDCNP----------LPCYNGGIC--VD 806
Query: 592 G----SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI-CECLPGFS 646
G CECAPGF GP C+ Q P C + + I+G C C PG +
Sbjct: 807 GVNWFRCECAPGFAGPDCR-------INIDECQSSP-CAYGATCVDEINGYRCSCPPGRA 858
Query: 647 GALCNQVCAGGYFGQDCAQLCSCANNGTCSPID-GSCQCFPGWIGKDCSQA-CPPGFWGP 704
G C +V FG+ C + +G+ D SC+C G +DCS+ C W P
Sbjct: 859 GPRCQEVIG---FGRSCWSRGTPFPHGSSWVEDCNSCRCLDG--RRDCSKVWCG---WKP 910
Query: 705 ACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI 764
A C G C ++ P C +C GA +
Sbjct: 911 CLLAGQPEALSAQCP------------LGQRCLEKAPGQCLRPPCEAWGEC--GAE-EPP 955
Query: 765 SGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIR--- 821
S C R+G H + CA T + + + +T + P + +
Sbjct: 956 STPCLPRSG----HLDNNCARLTLHFNRDHVPQ---GTTVGAICSGIRSLPATRAVARDR 1008
Query: 822 -----CDQAALMMEELNPYTKISPA---------LGAERHSVGAVT---GIMLLL----- 859
CD+A+ + SPA GA V A+T LLL
Sbjct: 1009 LLVLLCDRASSGASAVEVAVSFSPARDLPDSSLIQGAAHAIVAAITQRGNSSLLLAVTEV 1068
Query: 860 -------------FLIVVLLGLFA------------WHRRRQKEKGRDLAPR 886
L+ VL G F+ W R+R+KE+ R PR
Sbjct: 1069 KVETVVTGGSSTGLLVPVLCGAFSVLWLACVVLCVWWTRKRRKERERSRLPR 1120
Score = 182 bits (462), Expect = 1e-45
Identities = 196/739 (26%), Positives = 245/739 (33%), Gaps = 235/739 (31%)
Query: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFG 308
C + A C + C P D H+ CD G C G+MG C+E
Sbjct: 198 CDENYYSATCNKFCRP-------RNDFFGHY--TCDQY-GNKACMDGWMGKECKEAV--- 244
Query: 309 SFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADN 368
C Q C+ +GG P G C C G++G R C E + PGC
Sbjct: 245 -----CKQGCNLLHGGCTVP--GECRCSYGWQG-----RFCDECVPYPGCVHG------- 285
Query: 369 TISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG---CTCA 425
SC C C+ W G C++ + Y G PCT NG C + CTC
Sbjct: 286 --SCVE-PWQCNCETNWGGLLCDKD--LNYCGS--HHPCT--NGGTCINAEPDQYRCTCP 336
Query: 426 PGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSG 483
G+ G C + A T P C NGG+C V C C GW G C L
Sbjct: 337 DGYSGRNCEKAEHACTSNP-------CANGGSCHEVPSGFECHCPSGWSGPTCALDIDE- 388
Query: 484 TWGLNCNESCTCANGAACSPIDG-SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD 542
C + A G +DG C C W+G TC+L N E C +A
Sbjct: 389 -----CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDA-------NECEGKPCLNAF 436
Query: 543 GCDPVTG--HCCCLAGWTGIRC------------------------DSTCPPGRWGPNCS 576
C + G +C C+ GW GI C CP G G +C
Sbjct: 437 SCKNLIGGYYCDCIPGWKGINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCE 496
Query: 577 V------SCSCENGGSCSP-EDG-SCECAPGFRGPLCQR--------------------- 607
+ S C +GG C DG C C GF GPLC+
Sbjct: 497 LERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEG 556
Query: 608 ----ICPPGFYGHGCA---QPCPLCVHSSRPCHHISGI-CECLPGFSGALCNQVCA---- 655
CP F G C+ +PCP C I G + PG G + VC
Sbjct: 557 DYYCACPDDFGGKNCSVPREPCP-----GGACRVIDGCGSDAGPGMPGTAASGVCGPHGR 611
Query: 656 --------------GGYFGQDCAQLCS------CANNGTC-SPIDG-SCQCFPGWIGKDC 693
G+ G C + C N GTC +D C C GW G+ C
Sbjct: 612 CVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELC 671
Query: 694 SQ-------------------------ACPPGFWGPACFH------ACSCHNGASC--SA 720
AC G+ G C A +C NG +C S
Sbjct: 672 DTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSG 731
Query: 721 EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC--DHISGKCTCRTGFTGQH 778
+ C C PGW G C A C C NG +C S C CR G+ G+
Sbjct: 732 DTFRCACPPGWKGSTC-----AVAKNSSC-LPNPCVNGGTCVGSGASFSCICRDGWEGRT 785
Query: 779 CEQ-------------------------RCAPGTFGYGCQ------QLCECMNNSTC-DH 806
C CAPG G C+ Q C +TC D
Sbjct: 786 CTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDE 845
Query: 807 VTG-TCYCSPGFKGIRCDQ 824
+ G C C PG G RC +
Sbjct: 846 INGYRCSCPPGRAGPRCQE 864
Score = 138 bits (348), Expect = 2e-32
Identities = 119/411 (28%), Positives = 157/411 (38%), Gaps = 94/411 (22%)
Query: 435 VSCAAGTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN 490
V C Y C+ C N TC G+ C +GW G +C C
Sbjct: 196 VRCDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKEAV--------CK 246
Query: 491 ESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH 550
+ C +G P G C C+ GW G C+ C + C H +P
Sbjct: 247 QGCNLLHGGCTVP--GECRCSYGWQGRFCD----------ECVPYPGCVHGSCVEP--WQ 292
Query: 551 CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSC---SPEDGSCECAPGFRGPLCQR 607
C C W G+ CD C C NGG+C P+ C C G+ G C++
Sbjct: 293 CNCETNWGGLLCDKDLN------YCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK 346
Query: 608 ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCA-QL 666
H C +S PC + G C +P SG C+ C G+ G CA +
Sbjct: 347 A------EHAC---------TSNPCAN-GGSCHEVP--SGFECH--CPSGWSGPTCALDI 386
Query: 667 CSCANN-----GTC-SPIDG-SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCS 719
CA+N GTC +DG C C W+G C Q G C +A SC N
Sbjct: 387 DECASNPCAAGGTCVDQVDGFECICPEQWVGATC-QLDANECEGKPCLNAFSCKNLIG-- 443
Query: 720 AEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC-DHISG-KCTCRTGFTGQ 777
C C PGW G+ C DC QCQ+G +C D ++G +C C GF G+
Sbjct: 444 --GYYCDCIPGWKGINCHINV------NDCRG--QCQHGGTCKDLVNGYQCVCPRGFGGR 493
Query: 778 HCE---QRCA--PGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCD 823
HCE CA P G C+ L + + C+C GF G C+
Sbjct: 494 HCELERDECASSPCHSGGLCEDLADGFH----------CHCPQGFSGPLCE 534
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 217 bits (552), Expect = 5e-56
Identities = 254/924 (27%), Positives = 326/924 (35%), Gaps = 249/924 (26%)
Query: 97 DFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC-- 154
D C+P CVHG CV P C+CE WGG C + +C + C NG C
Sbjct: 274 DECVPY--PGCVHGSCVEPWQCNCETNWGGLLCDKDLN------YCGSHHPCTNGGTCIN 325
Query: 155 -NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCD--PRAGECLCAPGYT 211
P C C G+ G CE+ T C +G SC P EC C G++
Sbjct: 326 AEPDQYRCTCPDGYSGRNCEKAEHACTSN-------PCANGGSCHEVPSGFECHCPSGWS 378
Query: 212 GVYCE---ELCPPGSHGAHCELRCPCQNGGTC-HHITG-ECACPPGWTGAVCAQPCPPGT 266
G C + C PC GGTC + G EC CP W GA C
Sbjct: 379 GPTCALDIDECASN----------PCAAGGTCVDQVDGFECICPEQWVGATC-------- 420
Query: 267 FGQNCSQDC--PCHHGGQC-DHVTG-QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHN 322
Q DC C HGG C D V G QC C G+ G C+ E +C+ CH+
Sbjct: 421 --QLDVNDCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERD------ECAS-SPCHS 471
Query: 323 GGQCSPTTGA--CECEPGYKGPRCQ--ERLCPEGLHGPGCTLPCPCDADNTISCHPVTG- 377
GG C C C G+ GP C+ LC P PC N C+ + G
Sbjct: 472 GGLCEDLADGFHCHCPQGFSGPLCEVDVDLCE----------PSPC--RNGARCYNLEGD 519
Query: 378 -ACTCQPGWSGHHCN---ESCPVGYYG--DGC------QLPCTCQNG-----ADCHSITG 420
C C + G +C+ E CP G DGC +P T +G C S G
Sbjct: 520 YYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPG 579
Query: 421 G---CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC-SPVDG-SCTCKEGWQGLD 475
G C C GF G C + P C NGGTC VD C C GW+G
Sbjct: 580 GNFSCICDSGFTGTYCHENIDDCLGQP-------CRNGGTCIDEVDAFRCFCPSGWEGEL 632
Query: 476 C------TLP-------------------CPSGTWGLNCN------ESCTCANGAAC--S 502
C LP C G G C+ ++ TC+NG C S
Sbjct: 633 CDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDS 692
Query: 503 PIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRC 562
C+C PGW G TC + C C + + C C GW G C
Sbjct: 693 GDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSG----ASFSCICRDGWEGRTC 748
Query: 563 ---DSTCPPGRWGPNCSVSCSCENGGSCSPEDG----SCECAPGFRGPLCQRICPPGFYG 615
+ C P C NGG C DG CECAPGF GP C+
Sbjct: 749 THNTNDCNP----------LPCYNGGIC--VDGVNWFRCECAPGFAGPDCR-------IN 789
Query: 616 HGCAQPCPLCVHSSRPCHHISGI-CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGT 674
Q P C + + I+G C C PG +G C +V FG+ C + +G+
Sbjct: 790 IDECQSSP-CAYGATCVDEINGYRCSCPPGRAGPRCQEVIG---FGRSCWSRGTPFPHGS 845
Query: 675 CSPID-GSCQCFPGWIGKDCSQA-CPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWT 732
D SC+C G +DCS+ C W P A C
Sbjct: 846 SWVEDCNSCRCLDG--RRDCSKVWCG---WKPCLLAGQPEALSAQCP------------L 888
Query: 733 GLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGC 792
G C ++ P C +C GA + S C R+G H + CA T +
Sbjct: 889 GQRCLEKAPGQCLRPPCEAWGEC--GAE-EPPSTPCLPRSG----HLDNNCARLTLHFNR 941
Query: 793 QQLCECMNNSTCDHVTGTCYCSPGFKGIR--------CDQAALMMEELNPYTKISPA--- 841
+ + +T + P + + CD+A+ + SPA
Sbjct: 942 DHVPQ---GTTVGAICSGIRSLPATRAVARDRLLVLLCDRASSGASAVEVAVSFSPARDL 998
Query: 842 ------LGAERHSVGAVT---GIMLLL------------------FLIVVLLGLFA---- 870
GA V A+T LLL L+ VL G F+
Sbjct: 999 PDSSLIQGAAHAIVAAITQRGNSSLLLAVTEVKVETVVTGGSSTGLLVPVLCGAFSVLWL 1058
Query: 871 --------WHRRRQKEKGRDLAPR 886
W R+R+KE+ R PR
Sbjct: 1059 ACVVLCVWWTRKRRKERERSRLPR 1082
Score = 175 bits (443), Expect = 2e-43
Identities = 192/714 (26%), Positives = 238/714 (33%), Gaps = 223/714 (31%)
Query: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFG 308
C + A C + C P D H+ CD G C G+MG C+E
Sbjct: 198 CDENYYSATCNKFCRP-------RNDFFGHY--TCDQY-GNKACMDGWMGKECKEAV--- 244
Query: 309 SFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADN 368
C Q C+ +GG P G C C G++G R C E + PGC
Sbjct: 245 -----CKQGCNLLHGGCTVP--GECRCSYGWQG-----RFCDECVPYPGCVHG------- 285
Query: 369 TISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG---CTCA 425
SC C C+ W G C++ + Y G PCT NG C + CTC
Sbjct: 286 --SCVE-PWQCNCETNWGGLLCDKD--LNYCGS--HHPCT--NGGTCINAEPDQYRCTCP 336
Query: 426 PGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSG 483
G+ G C + A T P C NGG+C V C C GW G C L
Sbjct: 337 DGYSGRNCEKAEHACTSNP-------CANGGSCHEVPSGFECHCPSGWSGPTCALDIDE- 388
Query: 484 TWGLNCNESCTCANGAACSPIDG-SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD 542
C + A G +DG C C W+G TC+L D C C H
Sbjct: 389 -----CASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVND------CRGQCQ--HGG 435
Query: 543 GC-DPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV------SCSCENGGSCSP-EDG-S 593
C D V G+ C CP G G +C + S C +GG C DG
Sbjct: 436 TCKDLVNGYQC------------VCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFH 483
Query: 594 CECAPGFRGPLCQR-------------------------ICPPGFYGHGCA---QPCPLC 625
C C GF GPLC+ CP F G C+ +PCP
Sbjct: 484 CHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCP-- 541
Query: 626 VHSSRPCHHISGI-CECLPGFSGALCNQVCA------------------GGYFGQDCAQL 666
C I G + PG G + VC G+ G C +
Sbjct: 542 ---GGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHEN 598
Query: 667 CS------CANNGTC-SPIDG-SCQCFPGWIGKDCSQ----------------------- 695
C N GTC +D C C GW G+ C
Sbjct: 599 IDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDF 658
Query: 696 --ACPPGFWGPACFH------ACSCHNGASC--SAEDGACHCTPGWTGLFCTQRCPAAFF 745
AC G+ G C A +C NG +C S + C C PGW G C A
Sbjct: 659 YCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTC-----AVAK 713
Query: 746 GKDCGRVCQCQNGASC--DHISGKCTCRTGFTGQHCEQ---------------------- 781
C C NG +C S C CR G+ G+ C
Sbjct: 714 NSSC-LPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNW 772
Query: 782 ---RCAPGTFGYGCQ------QLCECMNNSTC-DHVTG-TCYCSPGFKGIRCDQ 824
CAPG G C+ Q C +TC D + G C C PG G RC +
Sbjct: 773 FRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQE 826
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 216 bits (550), Expect = 9e-56
Identities = 166/523 (31%), Positives = 207/523 (39%), Gaps = 114/523 (21%)
Query: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
RR SQ G Y+ G CI +C H + C PG+ + DS PH
Sbjct: 377 RRASQSLDGTYQGGGVCI-----DCQH-HTTGVNCERCLPGFYRSP-NHPLDS----PHV 425
Query: 143 SNRCQCQNG---ALCNPITGACVCAAGFRGWRCEELCAPGTHG----------------- 182
RC C++ C +TG C C F G RC+ +CA G G
Sbjct: 426 CRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFTGFPSCYPTPSSSNDTREQ 484
Query: 183 ---KGCQLPCQCR----HGASC--DPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCP 233
G + C C G +C DPR G CLC P + G +C ELC PG +G C+ C
Sbjct: 485 VLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC-ELCAPGFYGPGCQ-PCQ 542
Query: 234 CQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDH 285
C + G C TG+C C G+ GA C + C PG F Q C C G CD
Sbjct: 543 CSSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDE 601
Query: 286 VTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA---CECEPGYKGP 342
G+C C + G C + C G GF Q C C G GA C C PGY G
Sbjct: 602 -AGRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGT 659
Query: 343 RCQERLCPEGLHGPGCTLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYG 400
CQE C G HG +PC C A+ ++ +C P +G C+C+P +G C+ P Y
Sbjct: 660 ACQE--CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNF 717
Query: 401 DGC--------------------QLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSC 437
C Q+PC C+ G C C PGF G
Sbjct: 718 PYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCD------RCKPGFWG------- 764
Query: 438 AAGTYGPNCSSICSCNNGGT------CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNE 491
P + CSC+ GT C P G C CK G C C G +GL+ +
Sbjct: 765 -LSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQAD 822
Query: 492 -----SCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPD 525
SC C A G +C P G C C P G TC P D
Sbjct: 823 YFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
Score = 199 bits (507), Expect = 9e-51
Identities = 176/592 (29%), Positives = 217/592 (36%), Gaps = 115/592 (19%)
Query: 275 CPCH-HGGQCDHVTG------QCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCS 327
C CH H CD QC C G C CP F Q + ++ +C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCP--GFNQQPWKPATANSANECQ 357
Query: 328 PTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACT-CQPGWS 386
Y P R + L G + G C CQ +
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGT----------------YQGGGVCIDCQHHTT 401
Query: 387 GHHCNESCPVGYYGDGCQLP-------CTCQNG---ADCHSITGGCTCAPGFMGEVCAVS 436
G +C P Y L C C++ C +TG C C P F GE C V
Sbjct: 402 GVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDV- 460
Query: 437 CAAGTYG-PNCSSI-------------------CSCNNGGT----C--SPVDGSCTCKEG 470
CA G G P+C C C+ GT C P G C CK
Sbjct: 461 CAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPN 520
Query: 471 WQGLDCTLPCPSGTWGLNCNESCTCAN-GAA---CSPIDGSCSCTPGWLGDTCELPCPDG 526
+QG C L C G +G C + C C++ G A C P G C C G+ G TC+ C G
Sbjct: 521 FQGTHCEL-CAPGFYGPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCD-RCAPG 577
Query: 527 TFGLNCSEHCDCSHA----DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSC 581
F + C CS A +GCD G C C + G CD C PG G PNC +C+C
Sbjct: 578 YFHFPLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCD-RCRPGYHGFPNCQ-ACTC 634
Query: 582 ENGGSCSP---EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSS--RPCHHIS 636
+ G+ G C C PG+ G CQ C PGF+G PC S C S
Sbjct: 635 DPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPSCVPCHCSAEGSLHAACDPRS 693
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGS-------CQCFPGWI 689
G C C P +G C+ C G + + SC G +P+D + C C
Sbjct: 694 GQCSCRPRVTGLRCD-TCVPGAYNFPYCEAGSCHPAG-LAPVDPALPEAQVPCMCRAHVE 751
Query: 690 GKDCSQACPPGFWG-----PACFHACSCH------NGASCSAEDGACHCTPGWTGLFCTQ 738
G C + C PGFWG P CSC A C G C C P G C
Sbjct: 752 GPSCDR-CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS 810
Query: 739 RCPAAFFGKDCG-----RVCQCQNGA----SCDHISGKCTCRTGFTGQHCEQ 781
C FFG D R C+C G SC+ +G C CR G C +
Sbjct: 811 -CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Score = 196 bits (498), Expect = 1e-49
Identities = 184/631 (29%), Positives = 233/631 (36%), Gaps = 139/631 (22%)
Query: 108 VHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACV-CAAG 166
+ GRCV CH + CD+ +C CQ+ N G C C G
Sbjct: 296 IGGRCV----CHGH--------ADACDAKDPTDPFRLQCTCQH----NTCGGTCDRCCPG 339
Query: 167 F--RGWRCEELCAPGTHGKGCQLPCQCR-HGASC--DPRAGECLCAPGYTGVYCEELCPP 221
F + W+ A CQ C C H C DP + G Y
Sbjct: 340 FNQQPWKP----ATANSANECQ-SCNCYGHATDCYYDPEVDRRRASQSLDGTY------- 387
Query: 222 GSHGAHCELRCPCQNGGTC----HHITG-ECA-CPPGWTGAVCAQPCPPGTFGQNCSQDC 275
Q GG C HH TG C C PG+ + P P C + C
Sbjct: 388 -------------QGGGVCIDCQHHTTGVNCERCLPGFYRS----PNHPLDSPHVCRR-C 429
Query: 276 PCHHG---GQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQ---------------- 316
C G C+ +TG+C+C + G+RC + C G GF
Sbjct: 430 NCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSSSNDTREQVLPA 488
Query: 317 ----HCDCH----NGGQC--SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDA 366
+CDC G C P G C C+P ++G C+ LC G +GPGC PC C +
Sbjct: 489 GQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE--LCAPGFYGPGCQ-PCQCSS 545
Query: 367 DNTIS--CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD----CHSITG 420
C P TG C C+ G+ G C+ P ++ CQL C C C G
Sbjct: 546 PGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQL-CGCSPAGTLPEGCDE-AG 603
Query: 421 GCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCNNGGTCSPVDGS---CTCKEGWQGLDC 476
C C P F G C C G +G PNC + C+C+ G + G+ C C+ G+ G C
Sbjct: 604 RCLCQPEFAGPHCD-RCRPGYHGFPNCQA-CTCDPRGALDQLCGAGGLCRCRPGYTGTAC 661
Query: 477 TLPCPSGTWGLNCNESCTC-ANG---AACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNC 532
C G G C C A G AAC P G CSC P G C+ C G +
Sbjct: 662 Q-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFPY 719
Query: 533 SEHCDCSHADGCDPVTGH-------CCCLAGWTGIRCDSTCPPGRWG-----PNCSVSCS 580
E C H G PV C C A G CD C PG WG P CS
Sbjct: 720 CEAGSC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR-CKPGFWGLSPSNPEGCTRCS 777
Query: 581 CENGGS------CSPEDGSCECAPGFRGPLCQRICPPGFYG------HGCAQ-PCPLCVH 627
C+ G+ C P G C C P G C C GF+G GC C +
Sbjct: 778 CDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS-CKDGFFGLDQADYFGCRSCRCDIGGA 836
Query: 628 SSRPCHHISGICECLPGFSGALCNQVCAGGY 658
+ C +G+C C P G C++ Y
Sbjct: 837 LGQSCEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 160 bits (406), Expect = 4e-39
Identities = 125/376 (33%), Positives = 155/376 (41%), Gaps = 78/376 (20%)
Query: 151 GALCNPITGACVCAAGFRGWRCEELCAPGTHGK------GCQLPCQCR-HGASCDPRAGE 203
GAL + + C+C A +RG C+E CAPG + G +PCQC H C P +G
Sbjct: 1822 GALASNVE-LCLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGV 1879
Query: 204 CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCP 263
C+ C + GAHCE CQ G C + PCP
Sbjct: 1880 CVD------------CQHNTEGAHCER---CQAGFVSSRDDPSAPC--------VSCPCP 1916
Query: 264 PGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECP--FGS---FGFQCSQHC 318
N ++ C G QC C GY G C+ P FG+ G C Q C
Sbjct: 1917 LSVPSNNFAEGCVLRGGRT------QCLCKPGYAGASCERCAPGFFGNPLVLGSSC-QPC 1969
Query: 319 DCHNGGQ-------CSPTTGACE-CEPGYKGPRCQERLCPEGLHG----PGCTLPCPCDA 366
DC G C P TGAC C GPRC+ +C G +G PG C C
Sbjct: 1970 DCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE--ICAPGFYGNALLPGNCTRCDCTP 2027
Query: 367 DNTISCHPVTGACTCQPGWSGHHCNESCPVGYYG-DGCQ--LPCTC---QNGADCHSITG 420
T +C P +G C C+ G +G C + C G++G DGC PC C G++CH +G
Sbjct: 2028 CGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSG 2086
Query: 421 GCTCAPGFMGEVCAVSCAAGTYG---PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDC- 476
C C PG MG C CA G +G C C C GG C P G C C G G C
Sbjct: 2087 QCHCRPGTMGPQCR-ECAPGYWGLPEQGCRR-CQC-PGGRCDPHTGRCNCPPGLSGERCD 2143
Query: 477 ------TLPCPSGTWG 486
+P P G G
Sbjct: 2144 TCSQQHQVPVPGGPVG 2159
Score = 149 bits (375), Expect = 2e-35
Identities = 120/416 (28%), Positives = 157/416 (37%), Gaps = 92/416 (22%)
Query: 493 CTCANGA-ACSPIDGS------CSCTPGWLGDTCELPCPD---------GTFGLNCSEHC 536
C C A AC D + C+C G TC+ CP N + C
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 537 DC-SHADGC--DPVT---------------GHCC--CLAGWTGIRCDSTCPPGRW----- 571
+C HA C DP G C C TG+ C+ C PG +
Sbjct: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCER-CLPGFYRSPNH 418
Query: 572 ---GPNCSVSCSCENG---GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLC 625
P+ C+CE+ G+C G C C P F G C +C GF G P P
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFTGFPSCYPTPSS 477
Query: 626 VHSSR----PCHHIS--------------------GICECLPGFSGALCNQVCAGGYFGQ 661
+ +R P I G C C P F G C ++CA G++G
Sbjct: 478 SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHC-ELCAPGFYGP 536
Query: 662 DCAQLCSCANNGT----CSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGAS 717
C Q C C++ G C P G C+C G+ G C + P F P C C C +
Sbjct: 537 GC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLC-QLCGCSPAGT 594
Query: 718 CSA---EDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGK---CTCR 771
E G C C P + G C RC + G + C C + D + G C CR
Sbjct: 595 LPEGCDEAGRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCR 653
Query: 772 TGFTGQHCEQRCAPGTFGYGCQQLCECMN----NSTCDHVTGTCYCSPGFKGIRCD 823
G+TG C Q C+PG G+ C C ++ CD +G C C P G+RCD
Sbjct: 654 PGYTGTAC-QECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD 708
Score = 144 bits (362), Expect = 6e-34
Identities = 113/367 (30%), Positives = 136/367 (37%), Gaps = 94/367 (25%)
Query: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGAL----CNPITGACVCAAGFRGWRCE 173
C C+P + G C C +GP C CQC + + C+P TG C C GF G C+
Sbjct: 515 CLCKPNFQGTHCEL-CAPGFYGPGCQP-CQCSSPGVADDRCDPDTGQCRCRVGFEGATCD 572
Query: 174 ELCAPGT-HGKGCQLPCQCRHGAS----CDPRAGECLCAPGYTGVYCEELCPPGSHGAHC 228
CAPG H CQL C C + CD AG CLC P + G +C+ C PG HG
Sbjct: 573 R-CAPGYFHFPLCQL-CGCSPAGTLPEGCD-EAGRCLCQPEFAGPHCDR-CRPGYHGFPN 628
Query: 229 ELRCPCQNGGTCHHITGE---CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ--- 282
C C G + G C C PG+TG C Q C PG G C C G
Sbjct: 629 CQACTCDPRGALDQLCGAGGLCRCRPGYTGTAC-QECSPGFHGFPSCVPCHCSAEGSLHA 687
Query: 283 -CDHVTGQCHCTAGYMGDRCQEECPFGSFGF---------------------------QC 314
CD +GQC C G RC + C G++ F C
Sbjct: 688 ACDPRSGQCSCRPRVTGLRC-DTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMC 746
Query: 315 SQH--------------------------CDCHNGG------QCSPTTGACECEPGYKGP 342
H C C G +C P TG C C+P G
Sbjct: 747 RAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQ 806
Query: 343 RCQERLCPEGLHGP------GCTLPCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESC 394
C C +G G GC C CD + SC P TG C C+P G C+E
Sbjct: 807 ACAS--CKDGFFGLDQADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPA 863
Query: 395 PVGYYGD 401
Y D
Sbjct: 864 RDHYLPD 870
Score = 142 bits (359), Expect = 1e-33
Identities = 113/326 (34%), Positives = 141/326 (43%), Gaps = 60/326 (18%)
Query: 290 CHCTAGYMGDRCQEECPF------GSFGFQCSQHCDCH-NGGQCSPTTGAC-ECEPGYKG 341
C C A Y GD CQE P G F +C C CH + +C P +G C +C+ +G
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 342 PRCQERLCPEGL-------HGPGCTLPCPCD--ADNTISCHPVTGA---CTCQPGWSGHH 389
C+ C G P + PCP ++N + G C C+PG++G
Sbjct: 1890 AHCER--CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
Query: 390 CNESCPVGYYGD------GCQLPCTCQ-NG------ADCHSITGGCT-CAPGFMGEVCAV 435
C E C G++G+ CQ PC C NG +DC +TG C C G C +
Sbjct: 1948 C-ERCAPGFFGNPLVLGSSCQ-PCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
Query: 436 SCAAGTYG----PNCSSICSCNNGGT--CSPVDGSCTCKEGWQGLDCTLPCPSGTWGLN- 488
CA G YG P + C C GT C P G C CK G G C C G +G +
Sbjct: 2006 -CAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRCDR-CQEGHFGFDG 2063
Query: 489 CN--ESCTC---ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGL---NCSEHCDCSH 540
C C C A G+ C P G C C PG +G C C G +GL C C C
Sbjct: 2064 CGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLPEQGC-RRCQCP- 2120
Query: 541 ADGCDPVTGHCCCLAGWTGIRCDSTC 566
CDP TG C C G +G RCD TC
Sbjct: 2121 GGRCDPHTGRCNCPPGLSGERCD-TC 2145
Score = 142 bits (357), Expect = 2e-33
Identities = 112/321 (34%), Positives = 137/321 (42%), Gaps = 56/321 (17%)
Query: 551 CCCLAGWTGIRCDSTCP------PGRWGPNCSVSCSCE-NGGSCSPEDGSC-ECAPGFRG 602
C C A + G C P G + C V C C + C P G C +C G
Sbjct: 1831 CLCPASYRGDSCQECAPGFYRDVKGLFLGRC-VPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 603 PLCQRICPPGFYGHG------CAQ-PCPLCVHSSR---PCHHISGICECL--PGFSGALC 650
C+R C GF C PCPL V S+ C G +CL PG++GA C
Sbjct: 1890 AHCER-CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASC 1948
Query: 651 NQVCAGGYFGQ-----DCAQLCSCANNGT-------CSPIDGSCQ-CFPGWIGKDCSQAC 697
+ CA G+FG Q C C+ NG C P+ G+C+ C G C + C
Sbjct: 1949 ER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC-EIC 2006
Query: 698 PPGFWGPACFHA----CSCH--NGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD-CG 750
PGF+G A C C +C G C C G TG C RC FG D CG
Sbjct: 2007 APGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCG 2065
Query: 751 --RVCQC---QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECMNNS 802
R C C G+ C SG+C CR G G C + CAPG +G GC++ C+C
Sbjct: 2066 GCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQGCRR-CQCPGGR 2123
Query: 803 TCDHVTGTCYCSPGFKGIRCD 823
CD TG C C PG G RCD
Sbjct: 2124 -CDPHTGRCNCPPGLSGERCD 2143
Score = 140 bits (352), Expect = 8e-33
Identities = 115/363 (31%), Positives = 142/363 (39%), Gaps = 76/363 (20%)
Query: 324 GQCSPTTGACECEPGYKGPRCQERLCPEGLHGP------GCTLPCPCDADNTISCHPVTG 377
G + C C Y+G CQE C G + G +PC C + C P +G
Sbjct: 1822 GALASNVELCLCPASYRGDSCQE--CAPGFYRDVKGLFLGRCVPCQCHGHSD-RCLPGSG 1878
Query: 378 ACT-CQPGWSGHHCNESCPVGYYGDG-----------CQLPCTCQNGADCHSITGG---C 422
C CQ G HC E C G+ C L N A+ + GG C
Sbjct: 1879 VCVDCQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQC 1937
Query: 423 TCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPS 482
C PG+ G C CA G +G G +C P C C S
Sbjct: 1938 LCKPGYAGASCE-RCAPGFFGNPLVL------GSSCQP----CDC--------------S 1972
Query: 483 GTWGLNCNESCTCANGAACSPIDGSC-SCTPGWLGDTCELPCPDGTFGL-----NCSEHC 536
G N S C P+ G+C C G CE+ C G +G NC+ C
Sbjct: 1973 GNGDPNLLFS-------DCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTR-C 2023
Query: 537 DCSHA--DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCS--VSCSC---ENGGSCS 588
DC+ + CDP +GHC C AG TG RCD C G +G C C+C G C
Sbjct: 2024 DCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFDGCGGCRPCACGPAAEGSECH 2082
Query: 589 PEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGA 648
P+ G C C PG GP C R C PG++G Q C C C +G C C PG SG
Sbjct: 2083 PQSGQCHCRPGTMGPQC-RECAPGYWGLP-EQGCRRCQCPGGRCDPHTGRCNCPPGLSGE 2140
Query: 649 LCN 651
C+
Sbjct: 2141 RCD 2143
Score = 131 bits (330), Expect = 3e-30
Identities = 112/339 (33%), Positives = 137/339 (40%), Gaps = 73/339 (21%)
Query: 87 QCCPGYYESGDFCIPLCTEECVHGRCVSPDTCH-----CEPGWGGPDCSSGCDSDHWGPH 141
+C PG+Y + GRCV P CH C PG G C + G H
Sbjct: 1844 ECAPGFYRD--------VKGLFLGRCV-PCQCHGHSDRCLPGSG---VCVDCQHNTEGAH 1891
Query: 142 CSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRA 201
C +CQ G + + + C + C +GC L R G +
Sbjct: 1892 CE---RCQAGFVSSRDDPSAPCVS----CPCPLSVPSNNFAEGCVL----RGGRT----- 1935
Query: 202 GECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ------NG------GTCHHITGEC-A 248
+CLC PGY G CE C PG G L CQ NG C +TG C
Sbjct: 1936 -QCLCKPGYAGASCER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRG 1993
Query: 249 CPPGWTGAVCAQPCPPGTFGQ-----NCSQDCPCHHGGQ--CDHVTGQCHCTAGYMGDRC 301
C TG C + C PG +G NC++ C C G CD +G C C AG G RC
Sbjct: 1994 CLRHTTGPRC-EICAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRC 2051
Query: 302 QEECPFGSFGFQ-CS--QHCDCH---NGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG 355
+ C G FGF C + C C G +C P +G C C PG GP+C+E C G G
Sbjct: 2052 -DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE--CAPGYWG 2108
Query: 356 ---PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN 391
GC C C C P TG C C PG SG C+
Sbjct: 2109 LPEQGCR-RCQCPGGR---CDPHTGRCNCPPGLSGERCD 2143
Score = 108 bits (270), Expect = 3e-23
Identities = 89/309 (28%), Positives = 119/309 (38%), Gaps = 49/309 (15%)
Query: 532 CSEHCD-CSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGR---WGPNCSVSCSCENGGSC 587
C H D C D DP C C G CD CP W P + S + +C
Sbjct: 302 CHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNC 361
Query: 588 SPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI-CE-CLPGF 645
C P + + G G C HH +G+ CE CLPGF
Sbjct: 362 YGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQ---------HHTTGVNCERCLPGF 412
Query: 646 SGALCNQVCAGGYFGQDCAQLCSCANN---GTCSPIDGSCQCFPGWIGKDCSQACPPGFW 702
+ + + + + C+C ++ GTC + G C C P + G+ C C GF
Sbjct: 413 YRSPNHPLDS-----PHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD-VCAEGFT 466
Query: 703 G-PACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC 761
G P+C+ S S+ D P + C DC N
Sbjct: 467 GFPSCYPTPS-------SSNDTREQVLPAGQIVNC-----------DCSAAGTQGNACRK 508
Query: 762 DHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMN----NSTCDHVTGTCYCSPGF 817
D G+C C+ F G HCE CAPG +G GCQ C+C + + CD TG C C GF
Sbjct: 509 DPRVGRCLCKPNFQGTHCEL-CAPGFYGPGCQP-CQCSSPGVADDRCDPDTGQCRCRVGF 566
Query: 818 KGIRCDQAA 826
+G CD+ A
Sbjct: 567 EGATCDRCA 575
Score = 108 bits (269), Expect = 3e-23
Identities = 94/281 (33%), Positives = 117/281 (41%), Gaps = 56/281 (19%)
Query: 594 CECAPGFRGPLCQRICPPGFYGH------GCAQPCPLCVHSSRPCHHISGIC-ECLPGFS 646
C C +RG CQ C PGFY G PC HS R C SG+C +C
Sbjct: 1831 CLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDR-CLPGSGVCVDCQHNTE 1888
Query: 647 GALCNQVCAGGYFGQD-----CAQLCSC-----ANNGT--CSPIDG--SCQCFPGWIGKD 692
GA C + AG +D C C C +NN C G C C PG+ G
Sbjct: 1889 GAHCERCQAGFVSSRDDPSAPCVS-CPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
Query: 693 CSQACPPGFWGPACFHACSCH------NG------ASCSAEDGACH-CTPGWTGLFCTQR 739
C + C PGF+G SC NG + C GAC C TG C +
Sbjct: 1948 CER-CAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC-EI 2005
Query: 740 CPAAFFGK-----DCGRVCQCQ--NGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY-- 790
C F+G +C R C C +CD SG C C+ G TG+ C+ RC G FG+
Sbjct: 2006 CAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFDG 2063
Query: 791 --GCQQLCEC---MNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
GC+ C C S C +G C+C PG G +C + A
Sbjct: 2064 CGGCRP-CACGPAAEGSECHPQSGQCHCRPGTMGPQCRECA 2103
Score = 107 bits (267), Expect = 6e-23
Identities = 77/245 (31%), Positives = 99/245 (40%), Gaps = 35/245 (14%)
Query: 608 ICPPGFYGHGCAQPCPL------CVHSSRPCHHISGICECLPGFSGALCNQVCAG-GYFG 660
+ P Y G + PL H + +HIS P S C A F
Sbjct: 1378 VVPENVYSFGYLREEPLDKSYDFISHCAAQGYHIS------PSSSSLFCRNAAASLSLFY 1431
Query: 661 QDCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGA 716
+ A+ C C A TC P G C C IG+DCS+ C G+WG C C
Sbjct: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-GAR 1489
Query: 717 SCSAEDGACHCTPGWTGLFCTQRCPAAFFG-------KDC---GRVCQCQNGASCDHISG 766
C G C C P C C FG ++C G Q +CD SG
Sbjct: 1490 LCDELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSG 1548
Query: 767 KCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNST----CDHVTGTCYCSPGFKGIRC 822
+C CR TG+ C+ C+PG GY + C+C T CD +TG CYC +G +C
Sbjct: 1549 QCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC 1607
Query: 823 DQAAL 827
DQ +L
Sbjct: 1608 DQCSL 1612
Score = 100 bits (249), Expect = 7e-21
Identities = 67/195 (34%), Positives = 80/195 (41%), Gaps = 27/195 (13%)
Query: 146 CQCQN----GALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGAS-CDPR 200
C C G C P G C C A G C CA G G PC C GA CD
Sbjct: 1438 CGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC--GARLCDEL 1494
Query: 201 AGECLCAPGYTGVYCEELCPPGSHGAH----CELRCPCQNGG-------TCHHITGECAC 249
G+C+C P C LC P + G H CE C C G TC +G+C C
Sbjct: 1495 TGQCICPPRTIPPDC-LLCQPQTFGCHPLVGCE-ECNCSGPGIQELTDPTCDTDSGQCKC 1552
Query: 250 PPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEEC 305
P TG C C PG G + C CH G CD +TGQC+C G +C ++C
Sbjct: 1553 RPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQC 1610
Query: 306 PFGSFGFQCSQHCDC 320
G+F + C
Sbjct: 1611 SLGTFSLDAANPKGC 1625
Score = 97.8 bits (242), Expect = 5e-20
Identities = 74/233 (31%), Positives = 91/233 (39%), Gaps = 30/233 (12%)
Query: 416 HSITGGCTCAPGFMGEVCAVSCAA-GTYGPNCSSICSCNN----GGTCSPVDGSCTCKEG 470
H G +P C + A+ + N + C C+ G TC P G C C
Sbjct: 1403 HCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAH 1462
Query: 471 WQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG- 529
G DC+ C +G WG C C C + G C C P + C L C TFG
Sbjct: 1463 VIGRDCSR-CATGYWGFPNCRPCDCG-ARLCDELTGQCICPPRTIPPDCLL-CQPQTFGC 1519
Query: 530 ---LNCSEHCDCSHAD-------GCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVS 578
+ C E C+CS CD +G C C TG RCD TC PG G P C
Sbjct: 1520 HPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCD-TCSPGFHGYPRCR-P 1576
Query: 579 CSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQP--CPLC 625
C C G+ C P G C C +GP C + C G + A P C C
Sbjct: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSLGTFSLDAANPKGCTRC 1628
Score = 95.5 bits (236), Expect = 2e-19
Identities = 60/179 (33%), Positives = 77/179 (43%), Gaps = 26/179 (14%)
Query: 188 PCQCRH----GASCDPRAGECLCAPGYTGVYCEELCPPGSHG-AHCELRCPCQNGGT-CH 241
PC C G +C+P G+C C G C C G G +C PC G C
Sbjct: 1437 PCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR---PCDCGARLCD 1492
Query: 242 HITGECACPPGWTGAVCAQPCPPGTFGQNC---SQDCPCHHGG-------QCDHVTGQCH 291
+TG+C CPP C C P TFG + ++C C G CD +GQC
Sbjct: 1493 ELTGQCICPPRTIPPDCLL-CQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCK 1551
Query: 292 CTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQ----CSPTTGACECEPGYKGPRCQE 346
C G RC + C G G+ + CDCH G C P TG C C+ +GP+C +
Sbjct: 1552 CRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
Score = 91.3 bits (225), Expect = 4e-18
Identities = 87/313 (27%), Positives = 115/313 (36%), Gaps = 40/313 (12%)
Query: 385 WSGHHCNESCPVGYYGDGCQLPCTCQNGA---DCHSITGGCTCAPG----FMGEVCAVSC 437
W GH CP GY GC+ C+ A HS P ++ V V
Sbjct: 1325 WQGHANASFCPHGY---GCRTLVVCEGQALLDVTHSELTVTVRVPKGRWLWLDYVLVVPE 1381
Query: 438 AAGTYG--------PNCSSICSCN-NGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLN 488
++G + I C G SP S C+ L +L +G
Sbjct: 1382 NVYSFGYLREEPLDKSYDFISHCAAQGYHISPSSSSLFCRNAAASL--SLFYNNGARPCG 1439
Query: 489 CNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVT 548
C+E A G C P G C C +G C C G +G CDC A CD +T
Sbjct: 1440 CHE--VGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDCG-ARLCDELT 1495
Query: 549 GHCCCLAGWTGIRCDSTCPPGRWGPNCSVSC---SCENGG-------SCSPEDGSCECAP 598
G C C C C P +G + V C +C G +C + G C+C P
Sbjct: 1496 GQCICPPRTIPPDC-LLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 599 GFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP--CHHISGICECLPGFSGALCNQVCAG 656
G C C PGF+G+ +PC + P C ++G C C G C+Q C+
Sbjct: 1555 NVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSL 1612
Query: 657 GYFGQDCAQLCSC 669
G F D A C
Sbjct: 1613 GTFSLDAANPKGC 1625
Score = 85.1 bits (209), Expect = 3e-16
Identities = 60/203 (29%), Positives = 80/203 (39%), Gaps = 24/203 (11%)
Query: 267 FGQNCSQDCPCHH----GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHN 322
F N ++ C CH G C+ GQC C A +G C C G +GF + CDC
Sbjct: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCRPCDC-G 1487
Query: 323 GGQCSPTTGACECEPGYKGPRCQERLCPEGLHG----PGCTLPCPCDADNTI-----SCH 373
C TG C C P P C LC G GC C C +C
Sbjct: 1488 ARLCDELTGQCICPPRTIPPDCL--LCQPQTFGCHPLVGCE-ECNCSGPGIQELTDPTCD 1544
Query: 374 PVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD----CHSITGGCTCAPGFM 429
+G C C+P +G C ++C G++G PC C C +TG C C
Sbjct: 1545 TDSGQCKCRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQ 1603
Query: 430 GEVCAVSCAAGTYGPNCSSICSC 452
G C C+ GT+ + ++ C
Sbjct: 1604 GPKCD-QCSLGTFSLDAANPKGC 1625
Score = 82.8 bits (203), Expect = 2e-15
Identities = 75/310 (24%), Positives = 98/310 (31%), Gaps = 118/310 (38%)
Query: 87 QCCPGYYESGDFCIPLCT------EECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGP 140
+C PGY+ PLC + C C C+P + GP C H P
Sbjct: 573 RCAPGYFH-----FPLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFP 627
Query: 141 HCSNRCQCQNGALCNPITGA---CVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHG--- 194
+C C C + + GA C C G+ G C+E C+PG HG +PC C
Sbjct: 628 NCQ-ACTCDPRGALDQLCGAGGLCRCRPGYTGTACQE-CSPGFHGFPSCVPCHCSAEGSL 685
Query: 195 -ASCDPRAGECLCAPGYTGVYCEELCPPGSHG---------------------------- 225
A+CDPR+G+C C P TG+ C+ C PG++
Sbjct: 686 HAACDPRSGQCSCRPRVTGLRCDT-CVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPC 744
Query: 226 ---AHCE----------------------LRCPCQNGGT------CHHITGECACPPGWT 254
AH E RC C GT C TG+C C P
Sbjct: 745 MCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVC 804
Query: 255 GAVCAQ--------------------------------------PCPPGTFGQNCSQDCP 276
G CA C P T G CS+
Sbjct: 805 GQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPAR 864
Query: 277 CHHGGQCDHV 286
H+ H+
Sbjct: 865 DHYLPDLHHL 874
Score = 66.6 bits (161), Expect = 1e-10
Identities = 67/246 (27%), Positives = 89/246 (36%), Gaps = 62/246 (25%)
Query: 648 ALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPA-- 705
AL +Q+ + + + ++ S A G + C C + G C Q C PGF+
Sbjct: 1797 ALFSQISSAVFLRRVALEVASPAGQGALASNVELCLCPASYRGDSC-QECAPGFYRDVKG 1855
Query: 706 -----CFHACSCHNGAS-CSAEDGAC-HCTPGWTGLFCTQRCPAAFFGK----------- 747
C C CH + C G C C G C +RC A F
Sbjct: 1856 LFLGRCV-PCQCHGHSDRCLPGSGVCVDCQHNTEGAHC-ERCQAGFVSSRDDPSAPCVSC 1913
Query: 748 DCGRVCQCQNGASCDHISG---KCTCRTGFTGQHCEQRCAPGTF------GYGCQQLCEC 798
C N A + G +C C+ G+ G CE RCAPG F G CQ C+C
Sbjct: 1914 PCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQP-CDC 1971
Query: 799 MNN-------STCDHVTGTC-------------YCSPGFKG--------IRCDQAALMME 830
N S CD +TG C C+PGF G RCD E
Sbjct: 1972 SGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTE 2031
Query: 831 ELNPYT 836
+P++
Sbjct: 2032 ACDPHS 2037
Score = 60.1 bits (144), Expect = 1e-08
Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 33/153 (21%)
Query: 86 SQCCPGYYESGDFCIP------LCTE---ECV-HGRCVSPDTCHCEPGWGGPDCSSGCDS 135
S+C GY+ + C P LC E +C+ R + PD C+P G GC+
Sbjct: 1469 SRCATGYWGFPN-CRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527
Query: 136 DHWGPHCSNRCQCQNGAL-------CNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLP 188
C C + C+ +G C C G RC+ C+PG HG P
Sbjct: 1528 ----------CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFHGYPRCRP 1576
Query: 189 CQCRHGAS----CDPRAGECLCAPGYTGVYCEE 217
C C + CDP G+C C G C++
Sbjct: 1577 CDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
Score = 43.9 bits (102), Expect = 8e-04
Identities = 23/78 (29%), Positives = 32/78 (41%), Gaps = 6/78 (7%)
Query: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGA----LCNPITGACVCAAGFRGWRCE 173
C C P G C + H P C C C +C+P+TG C C +G +C+
Sbjct: 1550 CKCRPNVTGRRCDTCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCD 1608
Query: 174 ELCAPGTHGKGCQLPCQC 191
+ C+ GT P C
Sbjct: 1609 Q-CSLGTFSLDAANPKGC 1625
Score = 34.7 bits (78), Expect = 0.48
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 6/63 (9%)
Query: 80 TMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDT--CHCEPGWGGPDCSSGCDSDH 137
TM + +C PGY+ + C +C GRC P T C+C PG G C + C H
Sbjct: 2094 TMGPQCRECAPGYWGLPEQGCRRC--QCPGGRC-DPHTGRCNCPPGLSGERCDT-CSQQH 2149
Query: 138 WGP 140
P
Sbjct: 2150 QVP 2152
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 216 bits (549), Expect = 1e-55
Identities = 204/714 (28%), Positives = 265/714 (37%), Gaps = 206/714 (28%)
Query: 103 CTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA-- 160
C ++CV G TC C G+ G C + C+++ CQNG C +
Sbjct: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVNE------CASQ-PCQNGGTCTHGINSFR 334
Query: 161 CVCAAGFRGWRCEELCAPGTHGKGCQLPC---QCRHGASCDPRAGE--CLCAPGYTGVYC 215
C C AGF G CE Q PC +C+HG C G C+C GYTG C
Sbjct: 335 CQCPAGFGGPTCET----------AQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 216 E---ELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQP-----CPPGTF 267
E + C P PC NGG+C + G C +CA+P C G
Sbjct: 385 EMDVDDCSPD----------PCLNGGSCVDLVGNYTC-------LCAEPFKGLRCETGDH 427
Query: 268 G-QNCSQDCPCHHGGQC-DHVTGQ-CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGG 324
+ PCH+GG C D G C C G+MG C+E P C+C NGG
Sbjct: 428 PVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGG 478
Query: 325 QC-SPTTGACECEPGYKGPRCQERL----------CPEGLH--GPGCTLPCPCDADNTIS 371
+C T C+C G+ G C+ + CP+G + G + C C D+ S
Sbjct: 479 RCLGANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS 538
Query: 372 CHPVTGACTCQPGWSGHHCNE-------SCPVGYYGDGCQLP----CT---CQNGADCHS 417
H + C P ++G C+ CP G++G C+ C+ C+NG C
Sbjct: 539 -HSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKE 597
Query: 418 ITG--GCTCAPGFMGEVCAV----SCAAGTYGPNCSSICSCNNGGTCSPVDG--SCTCKE 469
G C+C F G C + SCA+G C+NGGTC G C C
Sbjct: 598 AGGEYHCSCPYRFTGRHCEIGKPDSCASG----------PCHNGGTCFHYIGKYKCDCPP 647
Query: 470 GWQGLDCTL-PCPSGTWGLNCNESCTCANGAACSPIDGS--CSCTPGWLGDTC--ELPCP 524
G+ G C + P P C S C NG C D C C G++G C E+ C
Sbjct: 648 GFSGRHCEIAPSP-------CFRS-PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCG 699
Query: 525 -------------------------DGTFGLN-------CSEH--------C-------- 536
D + L+ C H C
Sbjct: 700 PPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRS 759
Query: 537 -DCSHADGC-DPVTGH-CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGS 593
C H C D V G+ C C G+ G C+ R P C NGGSC G+
Sbjct: 760 QPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGA 812
Query: 594 CECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQV 653
C CP GF G C C S PC H G CE G LC V
Sbjct: 813 YVCR-----------CPAGFVGVHCETEVDAC--DSSPCQH-GGRCE--SGGGAYLC--V 854
Query: 654 CAGGYFGQDCAQLCS------CANNGTCSPIDG--SCQCFPGWIGKDCSQACPP 699
C +FG C + C G C +G SC C G+ G+DC++ P
Sbjct: 855 CPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 205 bits (521), Expect = 2e-52
Identities = 200/713 (28%), Positives = 252/713 (35%), Gaps = 211/713 (29%)
Query: 202 GECL--CAPGYTGVYCEELCPPGSHGAHCEL---RC---PCQNGGTCHHITGE--CACPP 251
G+C+ C G C C G G C L C PCQNGGTC H C CP
Sbjct: 282 GKCIDDCVTGNPSYTCS--CLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQCPA 339
Query: 252 GWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQ--CHCTAGYMGDRCQEECPFGS 309
G+ G C P C C HGGQC G C C AGY G C+ +
Sbjct: 340 GFGGPTCETAQSP------CDTK-ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVD--- 389
Query: 310 FGFQCSQHCDCHNGGQCSPTTG--ACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDAD 367
CS C NGG C G C C +KG RC+ P P L PC
Sbjct: 390 ---DCSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV----PDACLSAPCHNG 441
Query: 368 NTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSI-TGGCTCAP 426
T C C G+ G C E P D C+ C+NG C T C C
Sbjct: 442 GTCVDADQGYVCECPEGFMGLDCRERVP-----DDCE----CRNGGRCLGANTTLCQCPL 492
Query: 427 GFMGEVC-----AVSCAAGTYGPN---C-----SSICSCN-------------------N 454
GF G +C A+ C T P+ C S +C C+ N
Sbjct: 493 GFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFN 552
Query: 455 GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNES----CT---CANGAACSPIDGS 507
GG+C D S TC+ CP G G +C ++ C+ C NG C G
Sbjct: 553 GGSCDAHDDSYTCE-----------CPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
Query: 508 --CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDST 565
CSC + G CE+ PD C C H G +CD
Sbjct: 602 YHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIG---------------KYKCD-- 644
Query: 566 CPPGRWGPNCSVSCS------CENGGSCSPEDGS--CECAPGFRGPLCQ----------- 606
CPPG G +C ++ S C NGG+C D C C G+ G CQ
Sbjct: 645 CPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEV 704
Query: 607 --------------------------------RICPPGFYGHGCAQPCPLCVH----SSR 630
R+C P HG P C+ S+
Sbjct: 705 KHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP----HGVWSEPPQCLEIDECRSQ 760
Query: 631 PCHHISGICECLPGFSGALCNQVCAGGYFGQDC------AQLCSCANNGTCSPIDGS--C 682
PC H G C+ +G LC +C+ GY G C + C N G+C + G+ C
Sbjct: 761 PCLH-GGSCQ--DRVAGYLC--LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVC 815
Query: 683 QCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPA 742
+C G++G C AC + C +G C + GA C CP
Sbjct: 816 RCPAGFVGVHCETEVD------AC-DSSPCQHGGRCESGGGAYLCV-----------CPE 857
Query: 743 AFFGKDCGRVCQ------CQNGASCDHISGK--CTCRTGFTGQHCEQRCAPGT 787
+FFG C V C C +G CTC+ G+TG+ C + P T
Sbjct: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPT 910
Score = 192 bits (488), Expect = 1e-48
Identities = 186/665 (27%), Positives = 233/665 (35%), Gaps = 193/665 (29%)
Query: 276 PCHHGGQC--DHVTGQ----CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
PC +GG+C D VTG C C +G+ G RC + +C+ C NGG C+
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVN------ECASQ-PCQNGGTCTH- 328
Query: 330 TGACECEPGYKGPRCQERLCPEGLHGPGC-TLPCPCDADNTI---SCHPVTGA--CTCQP 383
G RCQ CP G GP C T PCD C G+ C CQ
Sbjct: 329 --------GINSFRCQ---CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQA 377
Query: 384 GWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGT 441
G++G C D C P C NG C + G C CA F G + C G
Sbjct: 378 GYTGAACEMDV------DDCS-PDPCLNGGSCVDLVGNYTCLCAEPFKG----LRCETGD 426
Query: 442 YG-PNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
+ P+ C+NGGTC D C C EG+ GLDC P + C C NG
Sbjct: 427 HPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNG 477
Query: 499 AACSPIDGS-CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGW 557
C + + C C G+ G CE + C+ + C C G C+
Sbjct: 478 GRCLGANTTLCQCPLGFFGLLCEFEIT----AMPCNMNTQCPDGGYCMEHGGSYLCV--- 530
Query: 558 TGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGS--CECAPGFRGPLCQRICPPGFYG 615
C + P+ S C NGGSC D S CEC GF G C++ P
Sbjct: 531 ----CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARP----- 581
Query: 616 HGCAQ-PCPLCVHSSRPCHHISGI--CECLPGFSGALCN----QVCAGGYFGQDCAQLCS 668
H C+ PC + C G C C F+G C CA G
Sbjct: 582 HLCSSGPC----RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG----------P 627
Query: 669 CANNGTCSPIDGS--CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA-- 724
C N GTC G C C PG+ G+ C A P F P C NG +C D
Sbjct: 628 CHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSP-------CVNGGTCEDRDTDFF 680
Query: 725 CHCTPGWTGLFC---------------------TQRCPAAFFGKDCG---------RVCQ 754
CHC G+ G C T+ A + D G RVCQ
Sbjct: 681 CHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQ 740
Query: 755 ---------------------CQNGASC-DHISGK-CTCRTGFTGQHCEQ---------- 781
C +G SC D ++G C C TG+ G HCE
Sbjct: 741 PHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPC 800
Query: 782 ---------------RCAPGTFGYGCQQLCECMNNSTCDH--------VTGTCYCSPGFK 818
RC G G C+ + ++S C H C C F
Sbjct: 801 RNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFF 860
Query: 819 GIRCD 823
G C+
Sbjct: 861 GYHCE 865
Score = 162 bits (411), Expect = 1e-39
Identities = 152/517 (29%), Positives = 192/517 (37%), Gaps = 128/517 (24%)
Query: 94 ESGDFCIP-LCTEECVH--GRCVSPD---TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQ 147
E+GD +P C H G CV D C C G+ G DC D C+
Sbjct: 423 ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD---------CE 473
Query: 148 CQNGALC-NPITGACVCAAGFRGWRCE-ELCAPGTHGKGCQLPCQCRHGASCDPRAGECL 205
C+NG C T C C GF G CE E+ A C + QC G C G L
Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEITA-----MPCNMNTQCPDGGYCMEHGGSYL 528
Query: 206 CA------------------PGYTGVYCEEL-------CPPGSHGAHCELR----C---P 233
C P + G C+ CP G HG HCE C P
Sbjct: 529 CVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP 588
Query: 234 CQNGGTCHHITGE--CACPPGWTGAVC--AQP------------------------CPPG 265
C+NGGTC GE C+CP +TG C +P CPPG
Sbjct: 589 CRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG 648
Query: 266 TFGQNCS---QDC---PCHHGGQCDHVTGQ--CHCTAGYMGDRCQEECPFGSFGFQCSQH 317
G++C C PC +GG C+ CHC AGYMG RCQ E G + +H
Sbjct: 649 FSGRHCEIAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGP--PEEVKH 706
Query: 318 CDCHNGGQCSPTTGACECEPGYK-GPRCQERLC-PEGLHGPGCTLPCPCDADNTISCHPV 375
G C+ GY + R+C P G+ P C + P
Sbjct: 707 ATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSE----PPQCLEIDECRSQPC 762
Query: 376 TGACTCQPGWSGHHCNESCPVGYYGDGCQL---PC---TCQNGADCHSITGG--CTCAPG 427
+CQ +G+ C C GY G C+L C C+NG C ++ G C C G
Sbjct: 763 LHGGSCQDRVAGYLC--LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAG 820
Query: 428 FMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGLDCTL---PCPS 482
F+G C A P C +GG C G+ C C E + G C PC S
Sbjct: 821 FVGVHCETEVDACDSSP-------CQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFS 873
Query: 483 GTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTC 519
G C +NG+ SC+C G+ G+ C
Sbjct: 874 SPCG--GRGYCLASNGS------HSCTCKVGYTGEDC 902
Score = 155 bits (392), Expect = 2e-37
Identities = 130/452 (28%), Positives = 174/452 (38%), Gaps = 107/452 (23%)
Query: 409 CQNGADC--HSITGG----CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVD 462
C NG C +TG C+C GF G C + P C NGGTC+
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQP-------CQNGGTCTHGI 330
Query: 463 GSCTCKEGWQGLDCTLPCPSGTWGLNCN------ESCTCANGAACSPIDGS--CSCTPGW 514
S C+ CP+G G C ++ C +G C +GS C C G+
Sbjct: 331 NSFRCQ-----------CPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
Query: 515 LGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDSTCPPGRWG 572
G CE+ D CS C + C + G+ C C + G+RC++ P
Sbjct: 380 TGAACEMDVDD------CSPD-PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPV--- 429
Query: 573 PNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCP---LCVHSS 629
P+ +S C NGG+C D +G +C+ CP GF G C + P C +
Sbjct: 430 PDACLSAPCHNGGTCVDAD---------QGYVCE--CPEGFMGLDCRERVPDDCECRNGG 478
Query: 630 RPCHHISGICECLPGFSGALCN-QVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGW 688
R + +C+C GF G LC ++ A C C + G C GS C
Sbjct: 479 RCLGANTTLCQCPLGFFGLLCEFEITA-----MPCNMNTQCPDGGYCMEHGGSYLCV--- 530
Query: 689 IGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKD 748
C P+ + C NG SC A D + C CP F GK
Sbjct: 531 ----CHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTC-----------ECPRGFHGKH 575
Query: 749 CGR----VCQ---CQNGASCDHISGK--CTCRTGFTGQHCE----QRCAPGTFGYGCQQL 795
C + +C C+NG +C G+ C+C FTG+HCE CA G
Sbjct: 576 CEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGP-------- 627
Query: 796 CECMNNSTCDHVTGT--CYCSPGFKGIRCDQA 825
C N TC H G C C PGF G C+ A
Sbjct: 628 --CHNGGTCFHYIGKYKCDCPPGFSGRHCEIA 657
Score = 102 bits (255), Expect = 1e-21
Identities = 93/322 (28%), Positives = 114/322 (35%), Gaps = 79/322 (24%)
Query: 89 CPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHW--GPHCSNRC 146
CP Y +G C + C G C + TC G DC G H P R
Sbjct: 606 CP-YRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRS 664
Query: 147 QCQNGALC--NPITGACVCAAGFRGWRC--EELCAP------------GT---------- 180
C NG C C C AG+ G RC E C P GT
Sbjct: 665 PCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYAC 724
Query: 181 -HGKGCQLPCQCR----HGASCDP----RAGECLCAPGYTGVYCEE-------LCPPGSH 224
G P + R HG +P EC P G C++ LC G
Sbjct: 725 DRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYE 784
Query: 225 GAHCEL---RC---PCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDCP 276
GAHCEL C PC+NGG+C ++ G C CP G+ G C + P
Sbjct: 785 GAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV-------DACDSSP 837
Query: 277 CHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD------CHNGGQCSPTT 330
C HGG+C+ G C CP FG+ C D C G C +
Sbjct: 838 CQHGGRCESGGGAYLCV-----------CPESFFGYHCETVSDPCFSSPCGGRGYCLASN 886
Query: 331 G--ACECEPGYKGPRCQERLCP 350
G +C C+ GY G C + L P
Sbjct: 887 GSHSCTCKVGYTGEDCAKELFP 908
Score = 72.4 bits (176), Expect = 2e-12
Identities = 57/186 (30%), Positives = 76/186 (40%), Gaps = 47/186 (25%)
Query: 657 GYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACF---HACS-- 711
G+ C L C N G C ID C G CS C GF G C + C+
Sbjct: 266 GHTTSVCLALRPCLNGGKC--ID---DCVTGNPSYTCS--CLSGFTGRRCHLDVNECASQ 318
Query: 712 -CHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV---C---QCQNGASCDHI 764
C NG +C+ + C +CPA F G C C +CQ+G C
Sbjct: 319 PCQNGGTCTHGINSFRC-----------QCPAGFGGPTCETAQSPCDTKECQHGGQCQVE 367
Query: 765 SGK--CTCRTGFTGQHCEQR---CAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGF 817
+G C C+ G+TG CE C+P C+N +C + G TC C+ F
Sbjct: 368 NGSAVCVCQAGYTGAACEMDVDDCSPDP----------CLNGGSCVDLVGNYTCLCAEPF 417
Query: 818 KGIRCD 823
KG+RC+
Sbjct: 418 KGLRCE 423
Score = 49.7 bits (117), Expect = 1e-05
Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 19/82 (23%)
Query: 574 NCSVSCSCENGGSCSP--EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP 631
NCS + C+NGG+C P + SC+C PGF+G C+ C+ SRP
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCEL----------------ACIKVSRP 1352
Query: 632 CHHISGICECLPGFSGALCNQV 653
C + + P + G +C+ V
Sbjct: 1353 CTRLFSETKAFPVWEGGVCHHV 1374
Score = 39.7 bits (91), Expect = 0.015
Identities = 18/40 (45%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 308 GSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQ 345
G+ CS++ C NGG C P A C+C PG+KG RC+
Sbjct: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 38.1 bits (87), Expect = 0.044
Identities = 24/62 (38%), Positives = 29/62 (46%), Gaps = 10/62 (16%)
Query: 233 PCQNGGTCHHITG----ECACPPGWTGAVCAQPC----PPGTFGQNCSQDCPCHHGGQCD 284
PCQNGGTC + G C C PG+ G C C P T + ++ P GG C
Sbjct: 1315 PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCH 1372
Query: 285 HV 286
HV
Sbjct: 1373 HV 1374
Score = 37.7 bits (86), Expect = 0.057
Identities = 17/35 (48%), Positives = 19/35 (54%), Gaps = 4/35 (11%)
Query: 403 CQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSC 437
CQ TC GAD HS C C PGF G C ++C
Sbjct: 1316 CQNGGTCVPGADAHS----CDCGPGFKGRRCELAC 1346
Score = 37.4 bits (85), Expect = 0.075
Identities = 19/38 (50%), Positives = 22/38 (57%), Gaps = 3/38 (7%)
Query: 488 NCNESCTCANGAACSP-IDG-SCSCTPGWLGDTCELPC 523
NC+E+ C NG C P D SC C PG+ G CEL C
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 37.4 bits (85), Expect = 0.075
Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 6/59 (10%)
Query: 191 CRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGA---HCELRC-PCQNGGTCHHI 243
C++G +C P A C C PG+ G CE C S E + P GG CHH+
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGVCHHV 1374
Score = 35.4 bits (80), Expect = 0.28
Identities = 20/43 (46%), Positives = 22/43 (51%), Gaps = 3/43 (6%)
Query: 440 GTYGPNCSSICSCNNGGTCSP-VDG-SCTCKEGWQGLDCTLPC 480
G NCS C NGGTC P D SC C G++G C L C
Sbjct: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 35.4 bits (80), Expect = 0.28
Identities = 18/38 (47%), Positives = 20/38 (52%), Gaps = 3/38 (7%)
Query: 141 HCSNRCQCQNGALCNPITGA--CVCAAGFRGWRCEELC 176
+CS CQNG C P A C C GF+G RCE C
Sbjct: 1310 NCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 33.9 bits (76), Expect = 0.82
Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)
Query: 265 GTFGQNCSQDCPCHHGGQCDHVTG----QCHCTAGYMGDRCQEEC 305
G NCS++ PC +GG C V G C C G+ G RC+ C
Sbjct: 1305 GNVPGNCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELAC 1346
Score = 33.9 bits (76), Expect = 0.82
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 669 CANNGTCSP-IDG-SCQCFPGWIGKDCSQAC 697
C N GTC P D SC C PG+ G+ C AC
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 33.1 bits (74), Expect = 1.4
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 8/45 (17%)
Query: 798 CMNNSTCDHVTG----TCYCSPGFKGIRCDQAALMMEELNPYTKI 838
C N TC V G +C C PGFKG RC+ A + + P T++
Sbjct: 1316 CQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVS--RPCTRL 1356
Score = 31.2 bits (69), Expect = 5.3
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 12/47 (25%)
Query: 747 KDCGRV---CQ---CQNGASCDHISG----KCTCRTGFTGQHCEQRC 783
KD G V C CQNG +C + G C C GF G+ CE C
Sbjct: 1302 KDIGNVPGNCSENPCQNGGTC--VPGADAHSCDCGPGFKGRRCELAC 1346
Score = 31.2 bits (69), Expect = 5.3
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 3/61 (4%)
Query: 373 HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEV 432
+P TC PG H C+ C G+ G C+L C + C + P + G V
Sbjct: 1314 NPCQNGGTCVPGADAHSCD--CGPGFKGRRCELAC-IKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 433 C 433
C
Sbjct: 1371 C 1371
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 213 bits (542), Expect = 8e-55
Identities = 111/321 (34%), Positives = 130/321 (40%), Gaps = 52/321 (16%)
Query: 381 CQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAG 440
C GW + P+ C+ P CQ C G C C PGF G C+ C
Sbjct: 41 CCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQ 93
Query: 441 TYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAA 500
+GP+C C C+ G C P G+C C+ + WG C C C
Sbjct: 94 YWGPDCRESCPCHPHGQCEPATGACQCQ-------------ADRWGARCEFPCACGPHGR 140
Query: 501 CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGI 560
C P G C C PGW TC PC T C + TG C C GW G
Sbjct: 141 CDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQ------------ATGACVCKPGWWGR 188
Query: 561 RCD----------------STCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPL 604
RC C PG WGP C C C G CS G C C PGFRG
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGFRGAR 247
Query: 605 CQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICE-CLPGFSGALCNQVCAGGYFGQDC 663
C+ CP G +G CA C C H + PC +G CE C PG++G C Q C G FG+ C
Sbjct: 248 CELPCPAGSHGVQCAHSCGRCKH-NEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESC 306
Query: 664 AQLC-SCANNGTCSPIDGSCQ 683
Q C C + C P G CQ
Sbjct: 307 EQQCPHCRHGEACEPDTGHCQ 327
Score = 210 bits (534), Expect = 6e-54
Identities = 111/290 (38%), Positives = 136/290 (46%), Gaps = 44/290 (15%)
Query: 87 QCCPGYYESGDFC-IPLCT--EECVHGR-CVSPDTCHCEPGWGGPDCSSGCDSDHWGPHC 142
QCC G+ + C IP+C + C CV P C C+PG+ G CSS C +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGK-----------------GC 185
C C C P TGAC C A G RCE CA G HG+ C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 186 QLPCQCRHGAS-CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL---RCPCQNG---- 237
+ PCQC A+ C+ G C+C PG+ G C C HG+ CE RC C+ G
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRC--NCHGSPCEQDSGRCACRPGWWGP 217
Query: 238 ----------GTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-PCHHGGQCDHV 286
G C +GEC CPPG+ GA C PCP G+ G C+ C C H C
Sbjct: 218 ECQQQCECVRGRCSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPD 277
Query: 287 TGQCH-CTAGYMGDRCQEECPFGSFGFQCSQHC-DCHNGGQCSPTTGACE 334
TG C C G+ G +CQ+ C G+FG C Q C C +G C P TG C+
Sbjct: 278 TGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
Score = 192 bits (488), Expect = 1e-48
Identities = 116/340 (34%), Positives = 142/340 (41%), Gaps = 62/340 (18%)
Query: 212 GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT--GAVCAQPCPPGTFGQ 269
G EL P G H C P + E C GW C P G
Sbjct: 16 GTQGSELDPKGQHV--CVASSP----------SAELQCCAGWRQKDQECTIPICEGP--D 61
Query: 270 NCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT 329
C +D C G C C G+ G C CP +G C + C CH GQC P
Sbjct: 62 ACQKDEVCVK-------PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPA 114
Query: 330 TGACECEPGYKGPRCQERLCPEGLHG------------PG-----CTLPCPCDADNTISC 372
TGAC+C+ G RC E C G HG PG C PC C+ C
Sbjct: 115 TGACQCQADRWGARC-EFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNT-AAARC 172
Query: 373 HPVTGACTCQPGWSGHHCNE----------------SCPVGYYGDGCQLPCTCQNGADCH 416
TGAC C+PGW G C+ +C G++G CQ C C G C
Sbjct: 173 EQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CS 231
Query: 417 SITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS-CNNGGTCSPVDGSC-TCKEGWQGL 474
+ +G CTC PGF G C + C AG++G C+ C C + CSP GSC +C+ GW G
Sbjct: 232 AASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGT 291
Query: 475 DCTLPCPSGTWGLNCNESCT-CANGAACSPIDGSCSCTPG 513
C PC GT+G +C + C C +G AC P G C G
Sbjct: 292 QCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSG 331
Score = 173 bits (439), Expect = 7e-43
Identities = 102/314 (32%), Positives = 128/314 (40%), Gaps = 57/314 (18%)
Query: 545 DPVTGHCC----------CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594
DP H C C AGW + D C P C +C+ C + G C
Sbjct: 23 DPKGQHVCVASSPSAELQCCAGWR--QKDQECTI----PICEGPDACQKDEVCV-KPGLC 75
Query: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC 654
C PGF G C CP ++G C + CP H C +G C+C GA C C
Sbjct: 76 RCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQ--CEPATGACQCQADRWGARCEFPC 133
Query: 655 A-----------------GGYFGQDCAQLCSCANNGT-CSPIDGSCQCFPGWIGKDCSQ- 695
A G++ C + C C C G+C C PGW G+ CS
Sbjct: 134 ACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
Query: 696 ---------------ACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRC 740
AC PG+WGP C C C G CSA G C C PG+ G C C
Sbjct: 194 CNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPC 252
Query: 741 PAAFFGKDCGRVC-QCQNGASCDHISGKC-TCRTGFTGQHCEQRCAPGTFGYGCQQLC-E 797
PA G C C +C++ C +G C +C G+ G C+Q C PGTFG C+Q C
Sbjct: 253 PAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPH 312
Query: 798 CMNNSTCDHVTGTC 811
C + C+ TG C
Sbjct: 313 CRHGEACEPDTGHC 326
Score = 159 bits (402), Expect = 1e-38
Identities = 83/227 (36%), Positives = 104/227 (45%), Gaps = 37/227 (16%)
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQC----------FP 686
G+C C PGF GA C+ C G Y+G DC + C C +G C P G+CQC FP
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 687 GWIGKD--CSQA-----CPPGFWGPACFHACSCHNGAS-CSAEDGACHCTPGWTGLFCTQ 738
G C A C PG+W C C C+ A+ C GAC C PGW G C+
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 739 RCPA----------------AFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQR 782
RC ++G +C + C+C G C SG+CTC GF G CE
Sbjct: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG-RCSAASGECTCPPGFRGARCELP 251
Query: 783 CAPGTFGYGCQQLC-ECMNNSTCDHVTGTC-YCSPGFKGIRCDQAAL 827
C G+ G C C C +N C TG+C C PG+ G +C Q L
Sbjct: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCL 298
Score = 55.1 bits (131), Expect = 3e-07
Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 4/66 (6%)
Query: 107 CVHGRCVSPDT--CH-CEPGWGGPDCSSGCDSDHWGPHCSNRC-QCQNGALCNPITGACV 162
C H SPDT C CEPGW G C C +G C +C C++G C P TG C
Sbjct: 268 CKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQ 327
Query: 163 CAAGFR 168
+G R
Sbjct: 328 RCSGSR 333
Score = 31.2 bits (69), Expect = 5.3
Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 3/41 (7%)
Query: 88 CCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPD 128
C PG + G+ C C C HG PDT HC+ G D
Sbjct: 297 CLPGTF--GESCEQQCPH-CRHGEACEPDTGHCQRCSGSRD 334
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 179 bits (454), Expect = 1e-44
Identities = 152/495 (30%), Positives = 201/495 (40%), Gaps = 102/495 (20%)
Query: 379 CTCQPGWSGHHCNESCPVGY-------YGDGCQLPCTCQNGAD-CHSITGGCTCAPGFMG 430
C C PG++G C ESC + +G C+ PC C A+ C +TG C
Sbjct: 724 CQCPPGYTGSSC-ESCWPRHRRVNGTIFGGICE-PCQCFGHAESCDDVTGEC-------- 773
Query: 431 EVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN 490
++C T GP C C G P G+ E Q C L PS + C+
Sbjct: 774 ----LNCKDHTGGPYCDK---CLPGFYGEPTKGT---SEDCQPCACPLNIPSNNFSPTCH 823
Query: 491 ESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG-----------LNCSEHCDCS 539
+ G C DG C G+ G CE C +G FG C+++ D S
Sbjct: 824 LDRSL--GLIC---DG---CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 540 HADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGP-----NCSVSCSCENGGS----CSP 589
CD ++G C C G TG C+ C G +G NC C C GGS C
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHS 932
Query: 590 EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCV-----HSSRPCHHISGICECLPG 644
+ G CEC +G C + C G +G A+ C C S C SG C C PG
Sbjct: 933 QTGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPG 990
Query: 645 FSGALCNQVCAGGYFG--QDCAQLCSCANNGT-CSPIDGSCQCFPGWIGKDCSQACPPGF 701
+G C++ CA GYF + C C++ G C P G C C P IG+ CS+ C P
Sbjct: 991 VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSK-CAPNT 1048
Query: 702 WGPACF---HACSCHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ 754
WG + AC+C S C+ G C+C P ++G CT+ C + +C
Sbjct: 1049 WGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCD 1107
Query: 755 C-------------QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG------YGCQQL 795
C SC +G+CTC+ G HC+ RC PG FG GC
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS- 1165
Query: 796 CECMNNST-CDHVTG 809
C C +T C G
Sbjct: 1166 CYCFGTTTQCSEAKG 1180
Score = 176 bits (446), Expect = 1e-43
Identities = 137/457 (29%), Positives = 178/457 (38%), Gaps = 92/457 (20%)
Query: 204 CLCAPGYTGVYCEELCPPGSH------GAHCELRCPCQNGG---TCHHITGECACPPGWT 254
C C PGYTG CE P G CE PCQ G +C +TGEC T
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICE---PCQCFGHAESCDDVTGECLNCKDHT 780
Query: 255 GAVCAQPCPPGTFG-------QNCSQDCPCHHGGQCDHVTGQCH-----------CTAGY 296
G C PG +G ++C Q C C ++ + CH C GY
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDC-QPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGY 839
Query: 297 MGDRCQEECPFGSFG-----------FQCSQHCDCHNGGQCSPTTGAC-ECEPGYKGPRC 344
G RC E C G FG QC+ + D G C +G+C C+PG G C
Sbjct: 840 TGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC 898
Query: 345 QERLCPEGLHGPGCTL----PCPCDADNTIS--CHPVTGACTCQPGWSGHHCNESCPVGY 398
+ LC +G G PC C+A + S CH TG C C+ G C + C G
Sbjct: 899 E--LCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKAGT 955
Query: 399 YG----DGCQLPCTCQN----GADCHSITGGCTCAPGFMGEVCAVSCAAGTYG---PNCS 447
+G GC +PC C + DC +G C C PG G+ C CA G + C+
Sbjct: 956 FGLQSARGC-VPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCT 1012
Query: 448 SICSCNN-GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID- 505
+ C C++ G C P G C C G C+ C TWG + C N + +D
Sbjct: 1013 A-CECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDF 1070
Query: 506 ------GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC-------------SHADGCDP 546
G C+C P + G C C G + CDC + C
Sbjct: 1071 QCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSD 1129
Query: 547 VTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
TG C C GI CD C PG++G + C +
Sbjct: 1130 QTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS 1165
Score = 174 bits (440), Expect = 5e-43
Identities = 145/475 (30%), Positives = 191/475 (40%), Gaps = 93/475 (19%)
Query: 116 DTCHCEPGWGGPDCSSGCDSDH-------WGPHCSNRCQCQNGA-LCNPITGACVCAAGF 167
+ C C PG+ G C S C H +G C CQC A C+ +TG C+
Sbjct: 722 EVCQCPPGYTGSSCES-CWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDH 779
Query: 168 RGWRCEELCAPGTHG-------KGCQLPCQCRHGASCDPRAGECL-----------CAPG 209
G + C PG +G + CQ PC C + + C C G
Sbjct: 780 TGGPYCDKCLPGFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG 838
Query: 210 YTGVYCEELC-----PPGSHGAHCELRCPCQNG------GTCHHITGEC-ACPPGWTGAV 257
YTG CE P G C+ C C + G+C ++G C C PG TG
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSCQ-PCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRY 897
Query: 258 CAQPCPPGTFG-----QNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFG 308
C + C G FG +NC Q C C+ GG C TGQC C A G RC ++C G
Sbjct: 898 C-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKAG 954
Query: 309 SFGFQCSQ---HCDCHNGGQCS---PTTGACECEPGYKGPRCQERLCPEG---LHGPGCT 359
+FG Q ++ C+C++ G S +G C C+PG G +C C G GCT
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR--CAHGYFNFQEGGCT 1012
Query: 360 LPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGY---YGDGCQLPCTCQN----G 412
C C +C P TG C C P G C++ P + GC+ C C
Sbjct: 1013 -ACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCK-ACNCSTVGSLD 1069
Query: 413 ADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCNNGGT-------------C 458
C+ TG C C P F G C C+ G + P C ++C C GT C
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC 1127
Query: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPG 513
S G CTCK +G+ C C G +GL+ C++ C CS G
Sbjct: 1128 SDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS-CYCFGTTTQCSEAKG 1180
Score = 158 bits (400), Expect = 2e-38
Identities = 125/393 (31%), Positives = 166/393 (42%), Gaps = 71/393 (18%)
Query: 499 AACSPIDGS-------CSCTPGWLGDTCELPCP-----DGTFGLNCSEHCDC-SHADGCD 545
A P DGS C C PG+ G +CE P +GT E C C HA+ CD
Sbjct: 708 AVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCD 767
Query: 546 PVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVS-----CSCENGGSCSPEDGSCE---- 595
VTG C TG C PG +G P S C+C + +C
Sbjct: 768 DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 596 -------CAPGFRGPLCQRICPPGFYGH-----GCAQPCP----LCVHSSRPCHHISGIC 639
C G+ GP C+R C G++G G QPC L C +SG C
Sbjct: 828 LGLICDGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSC 886
Query: 640 -ECLPGFSGALCNQVCAGGYFG-----QDCAQLCSCANNGT----CSPIDGSCQCFPGWI 689
C PG +G C ++CA GYFG ++C Q C C G+ C G C+C
Sbjct: 887 LICKPGTTGRYC-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 690 GKDCSQACPPGFWGPACFHA---CSCHNGASCS---AEDGACHCTPGWTGLFCTQRCPAA 743
G+ C + C G +G C+C++ S S E G C C PG TG C RC
Sbjct: 945 GQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHG 1002
Query: 744 FFGKDCG--RVCQCQN-GASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMN 800
+F G C+C + G +CD +G+C C G+ C +CAP T+G+ C+ N
Sbjct: 1003 YFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACN 1061
Query: 801 NST-------CDHVTGTCYCSPGFKGIRCDQAA 826
ST C+ TG C C P F G +C + +
Sbjct: 1062 CSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECS 1094
Score = 148 bits (374), Expect = 2e-35
Identities = 133/478 (27%), Positives = 169/478 (35%), Gaps = 139/478 (29%)
Query: 324 GQCSPTTGACECEPGYKGPRCQ-----ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 378
G + C+C PGY G C+ R + G C PC C + SC VTG
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICE-PCQC-FGHAESCDDVTGE 772
Query: 379 C-------------TCQPGWSGH---------------------------HCNES----- 393
C C PG+ G H + S
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 394 --CPVGYYGDGCQ-----------------LPCTCQNGAD------CHSITGGC-TCAPG 427
CPVGY G C+ PC C + D C S++G C C PG
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPG 892
Query: 428 FMGEVCAVSCAAGTYG-----PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTL 478
G C + CA G +G NC C CN GG+ C G C C+ QG C
Sbjct: 893 TTGRYCEL-CADGYFGDAVDAKNCQP-CRCNAGGSFSEVCHSQTGQCECRANVQGQRCD- 949
Query: 479 PCPSGTWGLNCNESCTCANGAACSPI---------DGSCSCTPGWLGDTCELPCPDGTFG 529
C +GT+GL C N C+ G C C PG G C+ C G F
Sbjct: 950 KCKAGTFGLQSARGCVPCN---CNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFN 1005
Query: 530 L---NCSEHCDCSH-ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV---SCSCE 582
C+ C+CSH + CDP TG C C G +C S C P WG + + +C+C
Sbjct: 1006 FQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCS 1063
Query: 583 NGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---------PLCVHSS 629
GS C+ G C C P F G C C G + + C C +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSET 1122
Query: 630 R--PCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCF 685
+ C +G C C G C++ C G FG D C+ SC CF
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDR-CRPGKFGLDAKNPLGCS----------SCYCF 1169
Score = 147 bits (371), Expect = 5e-35
Identities = 136/459 (29%), Positives = 176/459 (38%), Gaps = 91/459 (19%)
Query: 422 CTCAPGFMGEVCAVSC------AAGTYGPNCSSICSC-NNGGTCSPVDGSCTCKEGWQGL 474
C C PG+ G C SC GT C C + +C V G C
Sbjct: 724 CQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC--------- 773
Query: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCS-CTPGWLGDTCELPCPDGTFGLNCS 533
L C T G C++ C G P G+ C P C L P F C
Sbjct: 774 ---LNCKDHTGGPYCDK---CLPGFYGEPTKGTSEDCQPC----ACPLNIPSNNFSPTC- 822
Query: 534 EHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG----PNCSVS-CSCENG---- 584
H D S CD C G+TG RC+ C G +G P S C C +
Sbjct: 823 -HLDRSLGLICDG------CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 585 --GSCSPEDGSCE-CAPGFRGPLCQRICPPGFYGHGC----AQPCPLCVHSS--RPCHHI 635
GSC GSC C PG G C+ +C G++G QPC S CH
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ 933
Query: 636 SGICECLPGFSGALCNQVCAGGYFGQDCAQ---LCSCANNGTCS---PIDGSCQCFPGWI 689
+G CEC G C++ C G FG A+ C+C + G+ S G C C PG
Sbjct: 934 TGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT 992
Query: 690 GKDCSQACPPGFWG---PACFHACSC-HNGASCSAEDGACHCTPGWTGLFCTQRCPAAF- 744
GK C + C G++ C AC C H G +C + G C C P G C++ P +
Sbjct: 993 GKKCDR-CAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG 1050
Query: 745 --FGKDCGRVCQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCEC 798
C + C C S C+ +G+C C F+G C + C+ G + Y LC+C
Sbjct: 1051 HSITTGC-KACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCDC 1108
Query: 799 MNNST-------------CDHVTGTCYCSPGFKGIRCDQ 824
T C TG C C +GI CD+
Sbjct: 1109 FLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 94.7 bits (234), Expect = 4e-19
Identities = 86/338 (25%), Positives = 115/338 (34%), Gaps = 93/338 (27%)
Query: 84 RRSQCCPGYYES----GDFCIPL-CTEEC---VHGRC--VSPDTCHCEPGWGGPDCSSGC 133
R +C GY+ G C P C + + G C +S C+PG G C C
Sbjct: 843 RCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-C 901
Query: 134 DSDHWGPHCSNR----CQCQNGA----LCNPITGACVCAAGFRGWRCEEL---------- 175
++G + C+C G +C+ TG C C A +G RC++
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961
Query: 176 -------------------------CAPGTHGKGCQ--------------LPCQCRH-GA 195
C PG GK C C+C H G
Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGT-------CHHITGECA 248
+CDP+ G C+C P G C + C P + G C N T C+ TG+C
Sbjct: 1022 NCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN 1080
Query: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG-------------QCDHVTGQCHCTAG 295
C P ++GA C + C G + C C G C TGQC C
Sbjct: 1081 CHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVN 1139
Query: 296 YMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGAC 333
G C + C G FG C + C TT C
Sbjct: 1140 VEGIHC-DRCRPGKFGLDAKNPLGC-SSCYCFGTTTQC 1175
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/183 (33%), Positives = 78/183 (42%), Gaps = 45/183 (24%)
Query: 682 CQCFPGWIGKDCSQACPPGFW-----------GPACFHA--CSCHNGAS-CSAEDGAC-H 726
C C G+ G C +AC PGF+ GP C C+ +S C E C +
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 727 CTPGWTGLFCTQRCPAAFFG------KDCGRVCQCQNGASCDHISGKCT----------- 769
C G FC +RC ++G DC + C C +S ++ S C
Sbjct: 1439 CQHHTAGDFC-ERCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 770 CRTGFTGQHCEQRCAPGTFGY-----GCQQLCECMNNST----CDHVTGTCYCSPGFKGI 820
C G+ GQ+CE RCAPG G G Q CEC + CD VTG C C PG G
Sbjct: 1497 CPRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 821 RCD 823
+CD
Sbjct: 1556 KCD 1558
Score = 70.1 bits (170), Expect = 1e-11
Identities = 65/234 (27%), Positives = 84/234 (35%), Gaps = 67/234 (28%)
Query: 551 CCCLAGWTGIRCDSTCPPGRW-----------GPNCS--VSCSCENGGS-CSPEDGSCE- 595
C C G++G+ C++ C PG + GP V C C S C PE C+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 596 CAPGFRGPLCQRICPPGFYG------HGCAQ-PCPLCVHSSR--PCHHISGICE-----C 641
C G C+R C G+YG + C Q CPL S+ P G+ + C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 642 LPGFSGALCNQVCAGGYFGQD-----CAQLCSCANNGT----CSPIDGSCQCFPGWIGKD 692
G+ G C + CA GY G Q C C G+ C P+ G C C PG G+
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG 746
C C H H GW +FC C G
Sbjct: 1557 CD----------GCKH----------------WHAREGWECVFCGDECTGLLLG 1584
Score = 68.6 bits (166), Expect = 3e-11
Identities = 68/233 (29%), Positives = 83/233 (35%), Gaps = 63/233 (27%)
Query: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ---------- 404
G G T+ P D + C C G+SG C E+C G+Y Q
Sbjct: 1365 GRGTTMTPPAD---------LIEKCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTL 1414
Query: 405 ---LPCTCQNGAD-CHSITGGC-TCAPGFMGEVCAVSCAAGTYG-----PNCSSICSCNN 454
+PC C + C T C C G+ C CA G YG PN C+C
Sbjct: 1415 GTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE-RCALGYYGIVKGLPNDCQQCACPL 1473
Query: 455 GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGW 514
+ + SC EG CT CP G G C C PG+
Sbjct: 1474 ISSSNNFSPSCVA-EGLDDYRCTA-CPRGYEGQYCER------------------CAPGY 1513
Query: 515 LGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHCCCLAGWTGIRCD 563
G G G +C E C+C CDPVTG C C G TG +CD
Sbjct: 1514 TGSP-------GNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 67.8 bits (164), Expect = 5e-11
Identities = 56/185 (30%), Positives = 72/185 (38%), Gaps = 44/185 (23%)
Query: 246 ECACPPGWTGAVCAQPCPPGTF-----------GQNCSQDCPCH---HGGQCDHVTGQC- 290
+C CP G++G C + C PG + G PC H CD T C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 291 HCTAGYMGDRCQEECPFGSFGF------QCSQHCDC---HNGGQCSPTTGA--------C 333
+C GD C E C G +G C Q C C + SP+ A
Sbjct: 1438 NCQHHTAGDFC-ERCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 334 ECEPGYKGPRCQERLCPEGLHGP-----GCTLPCPCDADNT--ISCHPVTGACTCQPGWS 386
C GY+G C+ C G G G C CD + + C PVTG CTC+PG +
Sbjct: 1496 ACPRGYEGQYCER--CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT 1553
Query: 387 GHHCN 391
G C+
Sbjct: 1554 GRKCD 1558
Score = 66.6 bits (161), Expect = 1e-10
Identities = 63/211 (29%), Positives = 83/211 (39%), Gaps = 56/211 (26%)
Query: 594 CECAPGFRGPLCQRICPPGFYGH-------------GCAQPCPLCVHSSRPCHHISGICE 640
C+C G+ G C+ C PGFY G PC HSS C + IC+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL-CDPETSICQ 1437
Query: 641 -CLPGFSGALCNQVCAGGYFG------QDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDC 693
C +G C + CA GY+G DC Q C+C + + SC G C
Sbjct: 1438 NCQHHTAGDFCER-CALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVA-EGLDDYRC 1494
Query: 694 SQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVC 753
+ ACP G+ G C C PG+TG G C + C
Sbjct: 1495 T-ACPRGYEGQYCER------------------CAPGYTG-------SPGNPGGSC-QEC 1527
Query: 754 QCQNGAS----CDHISGKCTCRTGFTGQHCE 780
+C S CD ++G CTCR G TG+ C+
Sbjct: 1528 ECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 61.2 bits (147), Expect = 5e-09
Identities = 56/218 (25%), Positives = 78/218 (35%), Gaps = 63/218 (28%)
Query: 666 LCSCANNGTCSPIDGS-----CQCFPGWIGKDCSQACPPGF----WGPACF------HAC 710
+C C + P+D + C+C G C Q CP GF W F AC
Sbjct: 286 MCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCP-GFHQKPWRAGTFLTKTECEAC 344
Query: 711 SCHNGAS-CSAED------------------GAC-HCTPGWTGLFCTQRCPAAFFG---- 746
+CH A C ++ G C +CT G+ C + C FF
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC-ETCTDGFFRPKGV 403
Query: 747 -----KDCGRVCQCQNGASCDHIS-------------GKCTCRTGFTGQHCEQRCAPGTF 788
+ C + C C S + + G C C+TGF G C+ RCA G
Sbjct: 404 SPNYPRPC-QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD-RCARGYT 461
Query: 789 GYGCQQLCEC--MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
GY + C C + + D G C C +G C +
Sbjct: 462 GYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 60.8 bits (146), Expect = 6e-09
Identities = 47/140 (33%), Positives = 59/140 (42%), Gaps = 29/140 (20%)
Query: 146 CQCQ-NGALCNPITGACV-CAAGFRGWRCEELCAPGTHGKGCQLP-----CQCRHGASCD 198
CQC + +LC+P T C C G CE CA G +G LP C C +S +
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSN 1478
Query: 199 PRAGECL-----------CAPGYTGVYCEELCP-----PGSHGAHCELRCPCQNGGT--- 239
+ C+ C GY G YCE P PG+ G C+ C C G+
Sbjct: 1479 NFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPV 1537
Query: 240 -CHHITGECACPPGWTGAVC 258
C +TG C C PG TG C
Sbjct: 1538 PCDPVTGFCTCRPGATGRKC 1557
Score = 59.7 bits (143), Expect = 1e-08
Identities = 53/182 (29%), Positives = 72/182 (39%), Gaps = 41/182 (22%)
Query: 508 CSCTPGWLGDTCELPCPDGTFGLNCSEH-------------CDCS-HADGCDPVTGHCC- 552
C C G+ G +CE C G + L C C+ H+ CDP T C
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 553 CLAGWTGIRCDSTCPPGRWG-----PNCSVSCSC---ENGGSCSP-------EDGSCECA 597
C G C+ C G +G PN C+C + + SP +D C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 598 P-GFRGPLCQRICPPGFYGH-----GCAQPCPLCVHSSRP--CHHISGICECLPGFSGAL 649
P G+ G C+R C PG+ G G Q C + S P C ++G C C PG +G
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 650 CN 651
C+
Sbjct: 1557 CD 1558
Score = 58.5 bits (140), Expect = 3e-08
Identities = 66/248 (26%), Positives = 87/248 (35%), Gaps = 67/248 (27%)
Query: 493 CTCANGAACSPIDGS-----CSCTPGWLGDTCELPCPD--------GTFGLNCS-EHCDC 538
C C A P+D + C C GD+C+ CP GTF E C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 539 -SHADGC-----------------DPVTGHCC--CLAGWTGIRCDSTCPPGRWGPNCSVS 578
A+ C + G C C GI C+ TC G + P
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPK---G 402
Query: 579 CSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHH--IS 636
S C P C C P G L + +CV +
Sbjct: 403 VSPNYPRPCQP----CHCDP--IGSLNE-----------------VCVKDEKHARRGLAP 439
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS--PIDGSCQCFPGWIGKDCS 694
G C C GF G C++ CA GY G + C+C+ G+ + P G C C G DCS
Sbjct: 440 GSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498
Query: 695 QACPPGFW 702
+ C GF+
Sbjct: 499 R-CKSGFF 505
Score = 53.9 bits (128), Expect = 8e-07
Identities = 72/262 (27%), Positives = 100/262 (38%), Gaps = 49/262 (18%)
Query: 275 CPCH-HGGQC--DHVTGQ--CHCTAGYMGDRCQEECP--------FGSFGFQCS-QHCDC 320
C C+ H C D T + C C GD C + CP G+F + + C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 321 HNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH-GPGCTLPCPCDADNT--ISCHPVTG 377
H + EC R L G + G G + C NT I+C T
Sbjct: 347 HGKAE--------ECYYDENVARRNLSLNIRGKYIGGGVCINC---TQNTAGINCETCTD 395
Query: 378 ACTCQPGWSGH--------HCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFM 429
G S + HC+ P+G + C + A G C C GF
Sbjct: 396 GFFRPKGVSPNYPRPCQPCHCD---PIGSLNEVCVKD---EKHARRGLAPGSCHCKTGFG 449
Query: 430 GEVCAVSCAAGTYG-PNCSSICSCNNGGTCS--PVDGSCTCKEGWQGLDCTLPCPSGTWG 486
G C CA G G P+C + C+C+ G+ + P G C CKE +G DC+ C SG +
Sbjct: 450 GVSCD-RCARGYTGYPDCKA-CNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFN 506
Query: 487 LNCNESCTCANGAACSPIDGSC 508
L + C + CS + C
Sbjct: 507 LQEDNWKGC-DECFCSGVSNRC 527
Score = 50.4 bits (119), Expect = 9e-06
Identities = 49/167 (29%), Positives = 65/167 (38%), Gaps = 39/167 (23%)
Query: 82 YRRRSQCCPGYYESGDF---CIPLCTEECV-HGRCVSPDTC---HCEPGWGGPDCSSGCD 134
YR RSQ PG G C+P +C H P+T +C+ G C C
Sbjct: 1399 YRLRSQ--PGGRTPGPTLGTCVPC---QCNGHSSLCDPETSICQNCQHHTAGDFCER-CA 1452
Query: 135 SDHWG-----PHCSNRCQCQNGALCNPITGACV-----------CAAGFRGWRCEELC-- 176
++G P+ +C C + N + +CV C G+ G CE
Sbjct: 1453 LGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPG 1512
Query: 177 ---APGTHGKGCQLPCQCRHGAS----CDPRAGECLCAPGYTGVYCE 216
+PG G CQ C+C S CDP G C C PG TG C+
Sbjct: 1513 YTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 47.8 bits (112), Expect = 6e-05
Identities = 59/243 (24%), Positives = 79/243 (32%), Gaps = 62/243 (25%)
Query: 146 CQCQNGALCNPITGA-----CVCAAGFRGWRCEELCAPGTHGK----GCQLPCQCRHGAS 196
C C A P+ A C C G C++ C PG H K G L +
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQ-CCPGFHQKPWRAGTFLTKTECEACN 345
Query: 197 CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGA 256
C +A EC Y E + +R GG C + T T
Sbjct: 346 CHGKAEECY--------YDENVA---RRNLSLNIRGKYIGGGVCINCTQN-------TAG 387
Query: 257 VCAQPCPPGTF-----GQNCSQDC-PCHHGGQCDHV-------------------TGQCH 291
+ + C G F N + C PCH CD + G CH
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCH----CDPIGSLNEVCVKDEKHARRGLAPGSCH 443
Query: 292 CTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCS--PTTGACECEPGYKGPRCQERLC 349
C G+ G C + C G G+ + C+C G + P G C C+ +G C C
Sbjct: 444 CKTGFGGVSC-DRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR--C 500
Query: 350 PEG 352
G
Sbjct: 501 KSG 503
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 102 LCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCN--PIT 158
+C ++ H R ++P +CHC+ G+GG C C + G C C N P
Sbjct: 425 VCVKDEKHARRGLAPGSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKNEDPCF 483
Query: 159 GACVCAAGFRGWRCEELCAPG------THGKGCQLPCQC 191
G C+C G C C G + KGC C C
Sbjct: 484 GPCICKENVEGGDCSR-CKSGFFNLQEDNWKGCD-ECFC 520
Score = 40.4 bits (93), Expect = 0.009
Identities = 60/243 (24%), Positives = 82/243 (33%), Gaps = 61/243 (25%)
Query: 87 QCCPGYYE----SGDFCIPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSSGCDSDH-WGP 140
QCCPG+++ +G F E C HG+ + C+ + + S + G
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKA---EECYYDENVARRNLSLNIRGKYIGGG 376
Query: 141 HCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP- 199
C N Q G C C GF P PCQ H CDP
Sbjct: 377 VCINCTQNTAGINCE------TCTDGF--------FRPKGVSPNYPRPCQPCH---CDPI 419
Query: 200 ------------------RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH 241
G C C G+ GV C+ C G G C C G+ +
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKN 478
Query: 242 H--ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGD 299
G C C G C++ C G F N +D + CD +C C+ + +
Sbjct: 479 EDPCFGPCICKENVEGGDCSR-CKSGFF--NLQED----NWKGCD----ECFCSG--VSN 525
Query: 300 RCQ 302
RCQ
Sbjct: 526 RCQ 528
Score = 32.0 bits (71), Expect = 3.1
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 16/76 (21%)
Query: 767 KCTCRTGFTGQHCEQRCAPGTFGYGCQQ-------------LCECMNNST-CDHVTGTCY 812
KC C G++G CE C PG + Q C+C +S+ CD T C
Sbjct: 1379 KCDCPLGYSGLSCE-ACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 813 -CSPGFKGIRCDQAAL 827
C G C++ AL
Sbjct: 1438 NCQHHTAGDFCERCAL 1453
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 179 bits (454), Expect = 1e-44
Identities = 152/495 (30%), Positives = 201/495 (40%), Gaps = 102/495 (20%)
Query: 379 CTCQPGWSGHHCNESCPVGY-------YGDGCQLPCTCQNGAD-CHSITGGCTCAPGFMG 430
C C PG++G C ESC + +G C+ PC C A+ C +TG C
Sbjct: 724 CQCPPGYTGSSC-ESCWPRHRRVNGTIFGGICE-PCQCFGHAESCDDVTGEC-------- 773
Query: 431 EVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN 490
++C T GP C C G P G+ E Q C L PS + C+
Sbjct: 774 ----LNCKDHTGGPYCDK---CLPGFYGEPTKGT---SEDCQPCACPLNIPSNNFSPTCH 823
Query: 491 ESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFG-----------LNCSEHCDCS 539
+ G C DG C G+ G CE C +G FG C+++ D S
Sbjct: 824 LDRSL--GLIC---DG---CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 540 HADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGP-----NCSVSCSCENGGS----CSP 589
CD ++G C C G TG C+ C G +G NC C C GGS C
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQ-PCRCNAGGSFSEVCHS 932
Query: 590 EDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCV-----HSSRPCHHISGICECLPG 644
+ G CEC +G C + C G +G A+ C C S C SG C C PG
Sbjct: 933 QTGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPG 990
Query: 645 FSGALCNQVCAGGYFG--QDCAQLCSCANNGT-CSPIDGSCQCFPGWIGKDCSQACPPGF 701
+G C++ CA GYF + C C++ G C P G C C P IG+ CS+ C P
Sbjct: 991 VTGKKCDR-CAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSK-CAPNT 1048
Query: 702 WGPACF---HACSCHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ 754
WG + AC+C S C+ G C+C P ++G CT+ C + +C
Sbjct: 1049 WGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCD 1107
Query: 755 C-------------QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG------YGCQQL 795
C SC +G+CTC+ G HC+ RC PG FG GC
Sbjct: 1108 CFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS- 1165
Query: 796 CECMNNST-CDHVTG 809
C C +T C G
Sbjct: 1166 CYCFGTTTQCSEAKG 1180
Score = 176 bits (446), Expect = 1e-43
Identities = 137/457 (29%), Positives = 178/457 (38%), Gaps = 92/457 (20%)
Query: 204 CLCAPGYTGVYCEELCPPGSH------GAHCELRCPCQNGG---TCHHITGECACPPGWT 254
C C PGYTG CE P G CE PCQ G +C +TGEC T
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICE---PCQCFGHAESCDDVTGECLNCKDHT 780
Query: 255 GAVCAQPCPPGTFG-------QNCSQDCPCHHGGQCDHVTGQCH-----------CTAGY 296
G C PG +G ++C Q C C ++ + CH C GY
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDC-QPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGY 839
Query: 297 MGDRCQEECPFGSFG-----------FQCSQHCDCHNGGQCSPTTGAC-ECEPGYKGPRC 344
G RC E C G FG QC+ + D G C +G+C C+PG G C
Sbjct: 840 TGPRC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC 898
Query: 345 QERLCPEGLHGPGCTL----PCPCDADNTIS--CHPVTGACTCQPGWSGHHCNESCPVGY 398
+ LC +G G PC C+A + S CH TG C C+ G C + C G
Sbjct: 899 E--LCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKAGT 955
Query: 399 YG----DGCQLPCTCQN----GADCHSITGGCTCAPGFMGEVCAVSCAAGTYG---PNCS 447
+G GC +PC C + DC +G C C PG G+ C CA G + C+
Sbjct: 956 FGLQSARGC-VPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCD-RCAHGYFNFQEGGCT 1012
Query: 448 SICSCNN-GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID- 505
+ C C++ G C P G C C G C+ C TWG + C N + +D
Sbjct: 1013 A-CECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDF 1070
Query: 506 ------GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC-------------SHADGCDP 546
G C+C P + G C C G + CDC + C
Sbjct: 1071 QCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSD 1129
Query: 547 VTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
TG C C GI CD C PG++G + C +
Sbjct: 1130 QTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS 1165
Score = 174 bits (440), Expect = 5e-43
Identities = 145/475 (30%), Positives = 191/475 (40%), Gaps = 93/475 (19%)
Query: 116 DTCHCEPGWGGPDCSSGCDSDH-------WGPHCSNRCQCQNGA-LCNPITGACVCAAGF 167
+ C C PG+ G C S C H +G C CQC A C+ +TG C+
Sbjct: 722 EVCQCPPGYTGSSCES-CWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKDH 779
Query: 168 RGWRCEELCAPGTHG-------KGCQLPCQCRHGASCDPRAGECL-----------CAPG 209
G + C PG +G + CQ PC C + + C C G
Sbjct: 780 TGGPYCDKCLPGFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVG 838
Query: 210 YTGVYCEELC-----PPGSHGAHCELRCPCQNG------GTCHHITGEC-ACPPGWTGAV 257
YTG CE P G C+ C C + G+C ++G C C PG TG
Sbjct: 839 YTGPRCERCAEGYFGQPSVPGGSCQ-PCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRY 897
Query: 258 CAQPCPPGTFG-----QNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFG 308
C + C G FG +NC Q C C+ GG C TGQC C A G RC ++C G
Sbjct: 898 C-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKAG 954
Query: 309 SFGFQCSQ---HCDCHNGGQCS---PTTGACECEPGYKGPRCQERLCPEG---LHGPGCT 359
+FG Q ++ C+C++ G S +G C C+PG G +C C G GCT
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR--CAHGYFNFQEGGCT 1012
Query: 360 LPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGY---YGDGCQLPCTCQN----G 412
C C +C P TG C C P G C++ P + GC+ C C
Sbjct: 1013 -ACECSHLGN-NCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCK-ACNCSTVGSLD 1069
Query: 413 ADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCNNGGT-------------C 458
C+ TG C C P F G C C+ G + P C ++C C GT C
Sbjct: 1070 FQCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRC-NLCDCFLPGTDATTCDSETKKCSC 1127
Query: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPG 513
S G CTCK +G+ C C G +GL+ C++ C CS G
Sbjct: 1128 SDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCSS-CYCFGTTTQCSEAKG 1180
Score = 158 bits (400), Expect = 2e-38
Identities = 125/393 (31%), Positives = 166/393 (42%), Gaps = 71/393 (18%)
Query: 499 AACSPIDGS-------CSCTPGWLGDTCELPCP-----DGTFGLNCSEHCDC-SHADGCD 545
A P DGS C C PG+ G +CE P +GT E C C HA+ CD
Sbjct: 708 AVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCD 767
Query: 546 PVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVS-----CSCENGGSCSPEDGSCE---- 595
VTG C TG C PG +G P S C+C + +C
Sbjct: 768 DVTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRS 827
Query: 596 -------CAPGFRGPLCQRICPPGFYGH-----GCAQPCP----LCVHSSRPCHHISGIC 639
C G+ GP C+R C G++G G QPC L C +SG C
Sbjct: 828 LGLICDGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSC 886
Query: 640 -ECLPGFSGALCNQVCAGGYFG-----QDCAQLCSCANNGT----CSPIDGSCQCFPGWI 689
C PG +G C ++CA GYFG ++C Q C C G+ C G C+C
Sbjct: 887 LICKPGTTGRYC-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQ 944
Query: 690 GKDCSQACPPGFWGPACFHA---CSCHNGASCS---AEDGACHCTPGWTGLFCTQRCPAA 743
G+ C + C G +G C+C++ S S E G C C PG TG C RC
Sbjct: 945 GQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHG 1002
Query: 744 FFGKDCG--RVCQCQN-GASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMN 800
+F G C+C + G +CD +G+C C G+ C +CAP T+G+ C+ N
Sbjct: 1003 YFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACN 1061
Query: 801 NST-------CDHVTGTCYCSPGFKGIRCDQAA 826
ST C+ TG C C P F G +C + +
Sbjct: 1062 CSTVGSLDFQCNVNTGQCNCHPKFSGAKCTECS 1094
Score = 148 bits (374), Expect = 2e-35
Identities = 133/478 (27%), Positives = 169/478 (35%), Gaps = 139/478 (29%)
Query: 324 GQCSPTTGACECEPGYKGPRCQ-----ERLCPEGLHGPGCTLPCPCDADNTISCHPVTGA 378
G + C+C PGY G C+ R + G C PC C + SC VTG
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGICE-PCQC-FGHAESCDDVTGE 772
Query: 379 C-------------TCQPGWSGH---------------------------HCNES----- 393
C C PG+ G H + S
Sbjct: 773 CLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC 832
Query: 394 --CPVGYYGDGCQ-----------------LPCTCQNGAD------CHSITGGC-TCAPG 427
CPVGY G C+ PC C + D C S++G C C PG
Sbjct: 833 DGCPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPG 892
Query: 428 FMGEVCAVSCAAGTYG-----PNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTL 478
G C + CA G +G NC C CN GG+ C G C C+ QG C
Sbjct: 893 TTGRYCEL-CADGYFGDAVDAKNCQP-CRCNAGGSFSEVCHSQTGQCECRANVQGQRCD- 949
Query: 479 PCPSGTWGLNCNESCTCANGAACSPI---------DGSCSCTPGWLGDTCELPCPDGTFG 529
C +GT+GL C N C+ G C C PG G C+ C G F
Sbjct: 950 KCKAGTFGLQSARGCVPCN---CNSFGSKSFDCEESGQCWCQPGVTGKKCD-RCAHGYFN 1005
Query: 530 L---NCSEHCDCSH-ADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV---SCSCE 582
C+ C+CSH + CDP TG C C G +C S C P WG + + +C+C
Sbjct: 1006 FQEGGCTA-CECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCS 1063
Query: 583 NGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPC---------PLCVHSS 629
GS C+ G C C P F G C C G + + C C +
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSET 1122
Query: 630 R--PCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCF 685
+ C +G C C G C++ C G FG D C+ SC CF
Sbjct: 1123 KKCSCSDQTGQCTCKVNVEGIHCDR-CRPGKFGLDAKNPLGCS----------SCYCF 1169
Score = 147 bits (371), Expect = 5e-35
Identities = 136/459 (29%), Positives = 176/459 (38%), Gaps = 91/459 (19%)
Query: 422 CTCAPGFMGEVCAVSC------AAGTYGPNCSSICSC-NNGGTCSPVDGSCTCKEGWQGL 474
C C PG+ G C SC GT C C + +C V G C
Sbjct: 724 CQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGEC--------- 773
Query: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCS-CTPGWLGDTCELPCPDGTFGLNCS 533
L C T G C++ C G P G+ C P C L P F C
Sbjct: 774 ---LNCKDHTGGPYCDK---CLPGFYGEPTKGTSEDCQPC----ACPLNIPSNNFSPTC- 822
Query: 534 EHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG----PNCSVS-CSCENG---- 584
H D S CD C G+TG RC+ C G +G P S C C +
Sbjct: 823 -HLDRSLGLICDG------CPVGYTGPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFS 874
Query: 585 --GSCSPEDGSCE-CAPGFRGPLCQRICPPGFYGHGC----AQPCPLCVHSS--RPCHHI 635
GSC GSC C PG G C+ +C G++G QPC S CH
Sbjct: 875 IPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQ 933
Query: 636 SGICECLPGFSGALCNQVCAGGYFGQDCAQ---LCSCANNGTCS---PIDGSCQCFPGWI 689
+G CEC G C++ C G FG A+ C+C + G+ S G C C PG
Sbjct: 934 TGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVT 992
Query: 690 GKDCSQACPPGFWG---PACFHACSC-HNGASCSAEDGACHCTPGWTGLFCTQRCPAAF- 744
GK C + C G++ C AC C H G +C + G C C P G C++ P +
Sbjct: 993 GKKCDR-CAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWG 1050
Query: 745 --FGKDCGRVCQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCEC 798
C + C C S C+ +G+C C F+G C + C+ G + Y LC+C
Sbjct: 1051 HSITTGC-KACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRCNLCDC 1108
Query: 799 MNNST-------------CDHVTGTCYCSPGFKGIRCDQ 824
T C TG C C +GI CD+
Sbjct: 1109 FLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 94.7 bits (234), Expect = 4e-19
Identities = 86/338 (25%), Positives = 115/338 (34%), Gaps = 93/338 (27%)
Query: 84 RRSQCCPGYYES----GDFCIPL-CTEEC---VHGRC--VSPDTCHCEPGWGGPDCSSGC 133
R +C GY+ G C P C + + G C +S C+PG G C C
Sbjct: 843 RCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCEL-C 901
Query: 134 DSDHWGPHCSNR----CQCQNGA----LCNPITGACVCAAGFRGWRCEEL---------- 175
++G + C+C G +C+ TG C C A +G RC++
Sbjct: 902 ADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSA 961
Query: 176 -------------------------CAPGTHGKGCQ--------------LPCQCRH-GA 195
C PG GK C C+C H G
Sbjct: 962 RGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGN 1021
Query: 196 SCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGT-------CHHITGECA 248
+CDP+ G C+C P G C + C P + G C N T C+ TG+C
Sbjct: 1022 NCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCN 1080
Query: 249 CPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG-------------QCDHVTGQCHCTAG 295
C P ++GA C + C G + C C G C TGQC C
Sbjct: 1081 CHPKFSGAKCTE-CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVN 1139
Query: 296 YMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGAC 333
G C + C G FG C + C TT C
Sbjct: 1140 VEGIHC-DRCRPGKFGLDAKNPLGC-SSCYCFGTTTQC 1175
Score = 75.9 bits (185), Expect = 2e-13
Identities = 61/183 (33%), Positives = 78/183 (42%), Gaps = 45/183 (24%)
Query: 682 CQCFPGWIGKDCSQACPPGFW-----------GPACFHA--CSCHNGAS-CSAEDGAC-H 726
C C G+ G C +AC PGF+ GP C C+ +S C E C +
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 727 CTPGWTGLFCTQRCPAAFFG------KDCGRVCQCQNGASCDHISGKCT----------- 769
C G FC +RC ++G DC + C C +S ++ S C
Sbjct: 1439 CQHHTAGDFC-ERCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCTA 1496
Query: 770 CRTGFTGQHCEQRCAPGTFGY-----GCQQLCECMNNST----CDHVTGTCYCSPGFKGI 820
C G+ GQ+CE RCAPG G G Q CEC + CD VTG C C PG G
Sbjct: 1497 CPRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 821 RCD 823
+CD
Sbjct: 1556 KCD 1558
Score = 70.1 bits (170), Expect = 1e-11
Identities = 65/234 (27%), Positives = 84/234 (35%), Gaps = 67/234 (28%)
Query: 551 CCCLAGWTGIRCDSTCPPGRW-----------GPNCS--VSCSCENGGS-CSPEDGSCE- 595
C C G++G+ C++ C PG + GP V C C S C PE C+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 596 CAPGFRGPLCQRICPPGFYG------HGCAQ-PCPLCVHSSR--PCHHISGICE-----C 641
C G C+R C G+YG + C Q CPL S+ P G+ + C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 642 LPGFSGALCNQVCAGGYFGQD-----CAQLCSCANNGT----CSPIDGSCQCFPGWIGKD 692
G+ G C + CA GY G Q C C G+ C P+ G C C PG G+
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFG 746
C C H H GW +FC C G
Sbjct: 1557 CD----------GCKH----------------WHAREGWECVFCGDECTGLLLG 1584
Score = 68.6 bits (166), Expect = 3e-11
Identities = 68/233 (29%), Positives = 83/233 (35%), Gaps = 63/233 (27%)
Query: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ---------- 404
G G T+ P D + C C G+SG C E+C G+Y Q
Sbjct: 1365 GRGTTMTPPAD---------LIEKCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTL 1414
Query: 405 ---LPCTCQNGAD-CHSITGGC-TCAPGFMGEVCAVSCAAGTYG-----PNCSSICSCNN 454
+PC C + C T C C G+ C CA G YG PN C+C
Sbjct: 1415 GTCVPCQCNGHSSLCDPETSICQNCQHHTAGDFCE-RCALGYYGIVKGLPNDCQQCACPL 1473
Query: 455 GGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGW 514
+ + SC EG CT CP G G C C PG+
Sbjct: 1474 ISSSNNFSPSCVA-EGLDDYRCTA-CPRGYEGQYCER------------------CAPGY 1513
Query: 515 LGDTCELPCPDGTFGLNCSEHCDCSHADG----CDPVTGHCCCLAGWTGIRCD 563
G G G +C E C+C CDPVTG C C G TG +CD
Sbjct: 1514 TGSP-------GNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 67.8 bits (164), Expect = 5e-11
Identities = 56/185 (30%), Positives = 72/185 (38%), Gaps = 44/185 (23%)
Query: 246 ECACPPGWTGAVCAQPCPPGTF-----------GQNCSQDCPCH---HGGQCDHVTGQC- 290
+C CP G++G C + C PG + G PC H CD T C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 291 HCTAGYMGDRCQEECPFGSFGF------QCSQHCDC---HNGGQCSPTTGA--------C 333
+C GD C E C G +G C Q C C + SP+ A
Sbjct: 1438 NCQHHTAGDFC-ERCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 334 ECEPGYKGPRCQERLCPEGLHGP-----GCTLPCPCDADNT--ISCHPVTGACTCQPGWS 386
C GY+G C+ C G G G C CD + + C PVTG CTC+PG +
Sbjct: 1496 ACPRGYEGQYCER--CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGAT 1553
Query: 387 GHHCN 391
G C+
Sbjct: 1554 GRKCD 1558
Score = 66.6 bits (161), Expect = 1e-10
Identities = 63/211 (29%), Positives = 83/211 (39%), Gaps = 56/211 (26%)
Query: 594 CECAPGFRGPLCQRICPPGFYGH-------------GCAQPCPLCVHSSRPCHHISGICE 640
C+C G+ G C+ C PGFY G PC HSS C + IC+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL-CDPETSICQ 1437
Query: 641 -CLPGFSGALCNQVCAGGYFG------QDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDC 693
C +G C + CA GY+G DC Q C+C + + SC G C
Sbjct: 1438 NCQHHTAGDFCER-CALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVA-EGLDDYRC 1494
Query: 694 SQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVC 753
+ ACP G+ G C C PG+TG G C + C
Sbjct: 1495 T-ACPRGYEGQYCER------------------CAPGYTG-------SPGNPGGSC-QEC 1527
Query: 754 QCQNGAS----CDHISGKCTCRTGFTGQHCE 780
+C S CD ++G CTCR G TG+ C+
Sbjct: 1528 ECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 61.2 bits (147), Expect = 5e-09
Identities = 56/218 (25%), Positives = 78/218 (35%), Gaps = 63/218 (28%)
Query: 666 LCSCANNGTCSPIDGS-----CQCFPGWIGKDCSQACPPGF----WGPACF------HAC 710
+C C + P+D + C+C G C Q CP GF W F AC
Sbjct: 286 MCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCP-GFHQKPWRAGTFLTKTECEAC 344
Query: 711 SCHNGAS-CSAED------------------GAC-HCTPGWTGLFCTQRCPAAFFG---- 746
+CH A C ++ G C +CT G+ C + C FF
Sbjct: 345 NCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC-ETCTDGFFRPKGV 403
Query: 747 -----KDCGRVCQCQNGASCDHIS-------------GKCTCRTGFTGQHCEQRCAPGTF 788
+ C + C C S + + G C C+TGF G C+ RCA G
Sbjct: 404 SPNYPRPC-QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD-RCARGYT 461
Query: 789 GYGCQQLCEC--MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
GY + C C + + D G C C +G C +
Sbjct: 462 GYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 60.8 bits (146), Expect = 6e-09
Identities = 47/140 (33%), Positives = 59/140 (42%), Gaps = 29/140 (20%)
Query: 146 CQCQ-NGALCNPITGACV-CAAGFRGWRCEELCAPGTHGKGCQLP-----CQCRHGASCD 198
CQC + +LC+P T C C G CE CA G +G LP C C +S +
Sbjct: 1420 CQCNGHSSLCDPETSICQNCQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSN 1478
Query: 199 PRAGECL-----------CAPGYTGVYCEELCP-----PGSHGAHCELRCPCQNGGT--- 239
+ C+ C GY G YCE P PG+ G C+ C C G+
Sbjct: 1479 NFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQ-ECECDPYGSLPV 1537
Query: 240 -CHHITGECACPPGWTGAVC 258
C +TG C C PG TG C
Sbjct: 1538 PCDPVTGFCTCRPGATGRKC 1557
Score = 59.7 bits (143), Expect = 1e-08
Identities = 53/182 (29%), Positives = 72/182 (39%), Gaps = 41/182 (22%)
Query: 508 CSCTPGWLGDTCELPCPDGTFGLNCSEH-------------CDCS-HADGCDPVTGHCC- 552
C C G+ G +CE C G + L C C+ H+ CDP T C
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 553 CLAGWTGIRCDSTCPPGRWG-----PNCSVSCSC---ENGGSCSP-------EDGSCECA 597
C G C+ C G +G PN C+C + + SP +D C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 598 P-GFRGPLCQRICPPGFYGH-----GCAQPCPLCVHSSRP--CHHISGICECLPGFSGAL 649
P G+ G C+R C PG+ G G Q C + S P C ++G C C PG +G
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 650 CN 651
C+
Sbjct: 1557 CD 1558
Score = 58.5 bits (140), Expect = 3e-08
Identities = 66/248 (26%), Positives = 87/248 (35%), Gaps = 67/248 (27%)
Query: 493 CTCANGAACSPIDGS-----CSCTPGWLGDTCELPCPD--------GTFGLNCS-EHCDC 538
C C A P+D + C C GD+C+ CP GTF E C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 539 -SHADGC-----------------DPVTGHCC--CLAGWTGIRCDSTCPPGRWGPNCSVS 578
A+ C + G C C GI C+ TC G + P
Sbjct: 347 HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPK---G 402
Query: 579 CSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHH--IS 636
S C P C C P G L + +CV +
Sbjct: 403 VSPNYPRPCQP----CHCDP--IGSLNE-----------------VCVKDEKHARRGLAP 439
Query: 637 GICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS--PIDGSCQCFPGWIGKDCS 694
G C C GF G C++ CA GY G + C+C+ G+ + P G C C G DCS
Sbjct: 440 GSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS 498
Query: 695 QACPPGFW 702
+ C GF+
Sbjct: 499 R-CKSGFF 505
Score = 53.9 bits (128), Expect = 8e-07
Identities = 72/262 (27%), Positives = 100/262 (38%), Gaps = 49/262 (18%)
Query: 275 CPCH-HGGQC--DHVTGQ--CHCTAGYMGDRCQEECP--------FGSFGFQCS-QHCDC 320
C C+ H C D T + C C GD C + CP G+F + + C+C
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNC 346
Query: 321 HNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH-GPGCTLPCPCDADNT--ISCHPVTG 377
H + EC R L G + G G + C NT I+C T
Sbjct: 347 HGKAE--------ECYYDENVARRNLSLNIRGKYIGGGVCINC---TQNTAGINCETCTD 395
Query: 378 ACTCQPGWSGH--------HCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFM 429
G S + HC+ P+G + C + A G C C GF
Sbjct: 396 GFFRPKGVSPNYPRPCQPCHCD---PIGSLNEVCVKD---EKHARRGLAPGSCHCKTGFG 449
Query: 430 GEVCAVSCAAGTYG-PNCSSICSCNNGGTCS--PVDGSCTCKEGWQGLDCTLPCPSGTWG 486
G C CA G G P+C + C+C+ G+ + P G C CKE +G DC+ C SG +
Sbjct: 450 GVSCD-RCARGYTGYPDCKA-CNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFN 506
Query: 487 LNCNESCTCANGAACSPIDGSC 508
L + C + CS + C
Sbjct: 507 LQEDNWKGC-DECFCSGVSNRC 527
Score = 50.4 bits (119), Expect = 9e-06
Identities = 49/167 (29%), Positives = 65/167 (38%), Gaps = 39/167 (23%)
Query: 82 YRRRSQCCPGYYESGDF---CIPLCTEECV-HGRCVSPDTC---HCEPGWGGPDCSSGCD 134
YR RSQ PG G C+P +C H P+T +C+ G C C
Sbjct: 1399 YRLRSQ--PGGRTPGPTLGTCVPC---QCNGHSSLCDPETSICQNCQHHTAGDFCER-CA 1452
Query: 135 SDHWG-----PHCSNRCQCQNGALCNPITGACV-----------CAAGFRGWRCEELC-- 176
++G P+ +C C + N + +CV C G+ G CE
Sbjct: 1453 LGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPG 1512
Query: 177 ---APGTHGKGCQLPCQCRHGAS----CDPRAGECLCAPGYTGVYCE 216
+PG G CQ C+C S CDP G C C PG TG C+
Sbjct: 1513 YTGSPGNPGGSCQ-ECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 47.8 bits (112), Expect = 6e-05
Identities = 59/243 (24%), Positives = 79/243 (32%), Gaps = 62/243 (25%)
Query: 146 CQCQNGALCNPITGA-----CVCAAGFRGWRCEELCAPGTHGK----GCQLPCQCRHGAS 196
C C A P+ A C C G C++ C PG H K G L +
Sbjct: 287 CICYGHARACPLDPATNKSRCECEHNTCGDSCDQ-CCPGFHQKPWRAGTFLTKTECEACN 345
Query: 197 CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGA 256
C +A EC Y E + +R GG C + T T
Sbjct: 346 CHGKAEECY--------YDENVA---RRNLSLNIRGKYIGGGVCINCTQN-------TAG 387
Query: 257 VCAQPCPPGTF-----GQNCSQDC-PCHHGGQCDHV-------------------TGQCH 291
+ + C G F N + C PCH CD + G CH
Sbjct: 388 INCETCTDGFFRPKGVSPNYPRPCQPCH----CDPIGSLNEVCVKDEKHARRGLAPGSCH 443
Query: 292 CTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCS--PTTGACECEPGYKGPRCQERLC 349
C G+ G C + C G G+ + C+C G + P G C C+ +G C C
Sbjct: 444 CKTGFGGVSC-DRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR--C 500
Query: 350 PEG 352
G
Sbjct: 501 KSG 503
Score = 42.4 bits (98), Expect = 0.002
Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 12/99 (12%)
Query: 102 LCTEECVHGRC-VSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCN--PIT 158
+C ++ H R ++P +CHC+ G+GG C C + G C C N P
Sbjct: 425 VCVKDEKHARRGLAPGSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKNEDPCF 483
Query: 159 GACVCAAGFRGWRCEELCAPG------THGKGCQLPCQC 191
G C+C G C C G + KGC C C
Sbjct: 484 GPCICKENVEGGDCSR-CKSGFFNLQEDNWKGCD-ECFC 520
Score = 40.4 bits (93), Expect = 0.009
Identities = 60/243 (24%), Positives = 82/243 (33%), Gaps = 61/243 (25%)
Query: 87 QCCPGYYE----SGDFCIPLCTEEC-VHGRCVSPDTCHCEPGWGGPDCSSGCDSDH-WGP 140
QCCPG+++ +G F E C HG+ + C+ + + S + G
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKA---EECYYDENVARRNLSLNIRGKYIGGG 376
Query: 141 HCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP- 199
C N Q G C C GF P PCQ H CDP
Sbjct: 377 VCINCTQNTAGINCE------TCTDGF--------FRPKGVSPNYPRPCQPCH---CDPI 419
Query: 200 ------------------RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH 241
G C C G+ GV C+ C G G C C G+ +
Sbjct: 420 GSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLGSKN 478
Query: 242 H--ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGD 299
G C C G C++ C G F N +D + CD +C C+ + +
Sbjct: 479 EDPCFGPCICKENVEGGDCSR-CKSGFF--NLQED----NWKGCD----ECFCSG--VSN 525
Query: 300 RCQ 302
RCQ
Sbjct: 526 RCQ 528
Score = 32.0 bits (71), Expect = 3.1
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 16/76 (21%)
Query: 767 KCTCRTGFTGQHCEQRCAPGTFGYGCQQ-------------LCECMNNST-CDHVTGTCY 812
KC C G++G CE C PG + Q C+C +S+ CD T C
Sbjct: 1379 KCDCPLGYSGLSCE-ACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 813 -CSPGFKGIRCDQAAL 827
C G C++ AL
Sbjct: 1438 NCQHHTAGDFCERCAL 1453
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 178 bits (452), Expect = 2e-44
Identities = 185/675 (27%), Positives = 255/675 (37%), Gaps = 176/675 (26%)
Query: 148 CQNGALCNPITGACV--CAAGFRGWRCE---ELCAPGTHGKGCQLPCQCRHGASCDPRAG 202
C+NG + G C GF+G +CE + CA +H C++GA+C + G
Sbjct: 652 CKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECA--SH--------PCKNGATCIDQPG 701
Query: 203 E----------------CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCH--HIT 244
CLC PGY G+ CE+ C L C++ TC H++
Sbjct: 702 NYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDID------DCILNA-CEHNSTCKDLHLS 754
Query: 245 GECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCD--HVTGQCHCTAGYMGDRCQ 302
+C C W G C Q C + PC + C + + +C CT+G+ G C
Sbjct: 755 YQCVCLSDWEGNFCEQE------SNECKMN-PCKNNSTCTDLYKSYRCECTSGWTGQNCS 807
Query: 303 EECPFGSFGFQCSQHCD---CHNGGQCSPTT----GACECEPGYKGPRCQER--LCPEGL 353
EE CD C NGG C +T C C P Y G C +R LC + L
Sbjct: 808 EEI----------NECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLC-DLL 856
Query: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCN---ESCPVGYYGDGCQLPCTCQ 410
H P C C A + H C C+ + G +C + C L +CQ
Sbjct: 857 HNP-CRNNSTCLALVDANQH-----CICREEFEGKNCEIDVKDC----------LFLSCQ 900
Query: 411 NGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CT 466
+ DC + C C PGF G +C + CSS C N GTC + C
Sbjct: 901 DYGDCEDMVNNFRCICRPGFSGSLCEIEI------NECSSE-PCKNNGTCVDLTNRFFCN 953
Query: 467 CKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAAC-SPIDG-SCSCTPGWLGDTCELPCP 524
C+ + G C L +N + C + C DG +C C PG+ G CE+
Sbjct: 954 CEPEYHGPFCEL-------DVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLD 1006
Query: 525 DGTFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDST--------CPPGRWGPN 574
+ C C H C H C C +G+ G C++ C GR
Sbjct: 1007 E------CLSE-PCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTEL 1059
Query: 575 CS-VSCSCENGGS---CSPEDGSCECAPGFRGPLCQR-------ICPPGFYG-------H 616
+ CSC+ G+ C + C P CQ+ ICP G+ G
Sbjct: 1060 INEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSID 1119
Query: 617 GCAQP---CPLCVHS----SRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSC 669
CA+P +C++ P H C CLPGFSG C ++ C C
Sbjct: 1120 NCAEPELNSVICLNGGICVDGPGHTFD--CRCLPGFSGQFC-EININECSSSPCLHGADC 1176
Query: 670 ANNGTCSPIDG-SCQCFPGWIGKDCSQ--ACPPGFWGPACFHACSCHNGASCSAEDGA-C 725
++ I+G C+C PGW G C C P +C H N E G+ C
Sbjct: 1177 EDH-----INGYVCKCQPGWSGHHCENELECIPN----SCVHELCMEN------EPGSTC 1221
Query: 726 HCTPGW----TGLFC 736
CTPG+ GL C
Sbjct: 1222 LCTPGFMTCSIGLLC 1236
Score = 164 bits (415), Expect = 4e-40
Identities = 208/882 (23%), Positives = 301/882 (34%), Gaps = 256/882 (29%)
Query: 89 CPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPH------C 142
C G ++ F CTE+ + P+ D +S C W PH C
Sbjct: 493 CQGVIDAYFFLAANCTEDATYVN--DPE-----------DNNSSC----WFPHEGTKEIC 535
Query: 143 SNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAG 202
+N C C + C F W T + +C+H A C
Sbjct: 536 ANGCSCLSEEDSQEYRYLC-----FLRWAGNMYLENTTDDQ----ENECQHEAVCKDEIN 586
Query: 203 E--CLCAPGYTGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHHITGECACP--PGWTG 255
C C+ Y G C + C G+H G C ++ C C +
Sbjct: 587 RPRCSCSLSYIGRLCVVNVDYCL-GNHSISVH--------GLCLALSHNCNCSGLQRYER 637
Query: 256 AVCAQPCPPGTFGQNCSQDCP---CHHGGQCDHVTGQCH--CTAGYMGDRCQEECPFGSF 310
+C + ++DC C +G H+ G C G+ G +C+ +
Sbjct: 638 NIC----------EIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDID---- 683
Query: 311 GFQCSQHCDCHNGGQCSPTTG----------------ACECEPGYKGPRCQERLCPEGLH 354
+C+ H C NG C G +C C PGY G RC++ +
Sbjct: 684 --ECASH-PCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDI------ 734
Query: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD 414
C L C+ ++T ++ C C W G+ C + + C++ C+N +
Sbjct: 735 -DDCILNA-CEHNSTCKDLHLSYQCVCLSDWEGNFCEQE------SNECKMN-PCKNNST 785
Query: 415 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICS------CNNGGTC--SPVDGSCT 466
C + C C +G G NCS + C NGG C S + G
Sbjct: 786 CTDLYKSYRC-----------ECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFV 834
Query: 467 CKEGWQGLDCTLPCPSGTWGLNCNESCT--------CANGAACSPI---DGSCSCTPGWL 515
C CP G C++ C N + C + + C C +
Sbjct: 835 CL-----------CPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFE 883
Query: 516 GDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG-HCCCLAGWTGIRCDSTCPPGRWGPN 574
G CE+ D F L+C ++ DC D V C C G++G C+
Sbjct: 884 GKNCEIDVKDCLF-LSCQDYGDCE-----DMVNNFRCICRPGFSGSLCEIEIN------E 931
Query: 575 CSVSCSCENGGSCSPEDGS--CECAPGFRGPLCQR------------------------- 607
CS S C+N G+C C C P + GP C+
Sbjct: 932 CS-SEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNC 990
Query: 608 ICPPGFYGHGCAQPCPLCVHSSRPCHH----ISGI----CECLPGFSGALC----NQVCA 655
+C PG+ G C C+ S PC H I GI C+C GF G C N +
Sbjct: 991 LCAPGYTGINCEINLDECL--SEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLS 1048
Query: 656 GGYFGQDCAQL-----CSCANNGT---CSPIDGSCQCFPGWIGKDCSQA-------CPPG 700
C +L CSC +GT C C P C ++ CP G
Sbjct: 1049 NPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRG 1108
Query: 701 FWGPAC-----------FHACSCHNGASCSAEDGA---CHCTPGWTGLFCTQRCPAAFFG 746
+ G C ++ C NG C G C C PG++G FC
Sbjct: 1109 YTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEINI------ 1162
Query: 747 KDCGRVCQCQNGASC-DHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCD 805
+C C +GA C DHI+G +C PG G+ C+ EC+ NS C
Sbjct: 1163 NECSS-SPCLHGADCEDHINGYVC------------KCQPGWSGHHCENELECIPNS-CV 1208
Query: 806 HVT-------GTCYCSPGFKGIRCDQAALMMEELNPYTKISP 840
H TC C+PGF + C L +E+ T ++P
Sbjct: 1209 HELCMENEPGSTCLCTPGF--MTCSIGLLCGDEIRRITCLTP 1248
Score = 155 bits (391), Expect = 2e-37
Identities = 226/939 (24%), Positives = 322/939 (34%), Gaps = 246/939 (26%)
Query: 77 GLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPD-----TCHCEPGWGGPDCSS 131
GLR + Q C S +FC HG+C+S +CHC+P + G C
Sbjct: 162 GLRLNVTVKQQFCQESLSS-EFCSG-------HGKCLSEAWSKTYSCHCQPPFSGKYCQE 213
Query: 132 GCDSDHWGPHCSNRCQCQN-GALCNPITGACVCAAGFRGWRCEEL---CAPGT--HGKGC 185
D+ + P C N C N + CVC F G C E+ C P HG
Sbjct: 214 -LDACSFKP-CKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCS 271
Query: 186 QLP-----CQCRH---GASCDPRAGECL--------CAPGYTGVYCEELCPPGSHGAHCE 229
+ C+C G C+ A C+ P + Y E CP GS + E
Sbjct: 272 NITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICPNSSSAYTYE-CPKGSSSQNGE 330
Query: 230 L------RCPCQNGGTCHHITGE--CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGG 281
PCQNG C I+ + C C P +T +C Q + P +
Sbjct: 331 TDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSI-------QTSCESFPLRNNA 383
Query: 282 QCDHVTGQ--CHCTAGYMGDRCQ---------------EECPF---GSFGFQCSQHCD-- 319
C C C +G+ C+ EE F G F + C C
Sbjct: 384 TCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKN 443
Query: 320 ---------------CHNG----GQCSPTTGACECE-------PGYKGPRCQERLCPEGL 353
C+ G G C G + E G +G +CQ +
Sbjct: 444 PCWFLKNVYLIHQHLCYCGVTFHGICQ-DKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFF 502
Query: 354 HGPGCTLPCPC---DADNTISC---HPVT-----GACTCQPGWSGHHCNESCPVGYYGDG 402
CT DN SC H T C+C C + + G+
Sbjct: 503 LAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNM 562
Query: 403 CQLPCT------CQNGADCHSITG--GCTCAPGFMGEVCAVS---------------CAA 439
T CQ+ A C C+C+ ++G +C V+ C A
Sbjct: 563 YLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLA 622
Query: 440 GTYGPNCS-------SIC----------SCNNGGTCSPVDGSC--TCKEGWQGLDCTL-- 478
++ NCS +IC SC NG T + + G C G++G C +
Sbjct: 623 LSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDI 682
Query: 479 ------PCPSGTWGLNCNESCTCANGAACSPIDG-SCSCTPGWLGDTCELPCPDGTFGLN 531
PC +G ++ + C +DG SC C PG++G CE D LN
Sbjct: 683 DECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCI--LN 740
Query: 532 CSEH---CDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGP-----NC-----SVS 578
EH C H ++ C CL+ W G C+ + P C S
Sbjct: 741 ACEHNSTCKDLH------LSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYR 794
Query: 579 CSCEN---GGSCSPEDGSCECAPGFRGPLCQR---------ICPPGFYGHGCAQPCPLCV 626
C C + G +CS E C+ P G LC +CPP + G C Q LC
Sbjct: 795 CECTSGWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCD 854
Query: 627 HSSRPCHHISGICECLPGFSGALCNQVCAGGYFG---QDCAQLCSCANNGTCSPIDGSCQ 683
PC + S + +C + G +DC L SC + G C + + +
Sbjct: 855 LLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFL-SCQDYGDCEDMVNNFR 913
Query: 684 CFPGWIGKDCSQACPPGFWGPAC---FHACS---CHNGASC--SAEDGACHCTPGWTGLF 735
C C PGF G C + CS C N +C C+C P + G F
Sbjct: 914 CI-----------CRPGFSGSLCEIEINECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPF 962
Query: 736 C---TQRCPAAFFGKDCGRVCQCQNGASCDHISG--KCTCRTGFTGQHCEQRCAPGTFGY 790
C +C ++ C + +C + + C C G+TG +CE
Sbjct: 963 CELDVNKC----------KISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLD------ 1006
Query: 791 GCQQLCE-CMNNSTC-DHVTG-TCYCSPGFKGIRCDQAA 826
+ L E C+++ C D + TC C GF G C+ A
Sbjct: 1007 --ECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNA 1043
Score = 63.5 bits (153), Expect = 1e-09
Identities = 87/321 (27%), Positives = 119/321 (37%), Gaps = 65/321 (20%)
Query: 522 PCPDGTFGLNCS-EHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV--S 578
PCP G LN + + C + + +GH CL+ C P G C +
Sbjct: 158 PCPLG-LRLNVTVKQQFCQESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDA 216
Query: 579 CS---CENGGSC-------SPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHS 628
CS C+N GSC + C C P F G C I G QP +C H
Sbjct: 217 CSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEII-------GQCQP-HVCFHG 268
Query: 629 SRPCHHISG---ICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCF 685
+ C +I+ ICEC FSG C +V A + C L G C P S +
Sbjct: 269 N--CSNITSNSFICECDEQFSGPFC-EVSA-----KPCVSLLFW-KRGIC-PNSSSAYTY 318
Query: 686 PGWIGKDCSQACPPGFWGPACFHACSCHNGASCS--AEDGACHCTPGWTGLFCTQRCPAA 743
G G + F C NG C + D C C+P +T L C
Sbjct: 319 ECPKGSSSQN----GETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLC------- 367
Query: 744 FFGKDCGRVCQC---QNGASCDHISGK--CTCRTGFTGQHCEQRCAPGTFGYGCQQL-CE 797
K C+ +N A+C C+C +GFT ++CE+ C+ L
Sbjct: 368 ---KSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCEKAID------HCKLLSIN 418
Query: 798 CMNNSTCDHVTG--TCYCSPG 816
C+N C ++ G C PG
Sbjct: 419 CLNEEWCFNIIGRFKYVCIPG 439
Score = 47.8 bits (112), Expect = 6e-05
Identities = 37/94 (39%), Positives = 42/94 (44%), Gaps = 15/94 (15%)
Query: 655 AGGYFGQDCAQLCS---CANNGTCSPIDGS--CQCFPGWIGKDCSQ---ACPPGFWGPAC 706
AG GQ A CS C N GTC S C C GW G C++ C P P
Sbjct: 2602 AGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP-- 2659
Query: 707 FHACSCHNGASC-SAEDG-ACHCTPGWTGLFCTQ 738
H CS GA+C S G C C G TG++C Q
Sbjct: 2660 -HHCS--RGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 47.0 bits (110), Expect = 9e-05
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 6/74 (8%)
Query: 712 CHNGASC--SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI--SGK 767
C NG +C S C+CT GW G FCT+ D C GA+C +
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH--HCSRGATCISLPHGYT 2676
Query: 768 CTCRTGFTGQHCEQ 781
C C G TG +CEQ
Sbjct: 2677 CFCPLGTTGIYCEQ 2690
Score = 47.0 bits (110), Expect = 9e-05
Identities = 25/75 (33%), Positives = 35/75 (46%), Gaps = 9/75 (12%)
Query: 668 SCANNGTCSPIDG---SCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGA 724
+C N G C+ ++G SC+C P W G C+Q+ C H C S S +
Sbjct: 2883 TCRNGGECT-VNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQSFSY---S 2936
Query: 725 CHCTPGWTGLFCTQR 739
C CT GW G +C +
Sbjct: 2937 CLCTLGWVGRYCENK 2951
Score = 43.9 bits (102), Expect = 8e-04
Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 8/97 (8%)
Query: 125 GGPDCSSGCDSDHWGPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHG 182
G P+ H P CS +C NG C + + C C G++G C E + T
Sbjct: 2598 GHPNAGRSVGQCHASP-CS-LMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS--TCD 2653
Query: 183 KGCQLPCQCRHGASCD--PRAGECLCAPGYTGVYCEE 217
P C GA+C P C C G TG+YCE+
Sbjct: 2654 PEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 43.9 bits (102), Expect = 8e-04
Identities = 25/77 (32%), Positives = 35/77 (45%), Gaps = 15/77 (19%)
Query: 494 TCANGAACSPIDG---SCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDP---V 547
TC NG C+ ++G SC C P W G+TC ++C + C H C P
Sbjct: 2883 TCRNGGECT-VNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSF 2933
Query: 548 TGHCCCLAGWTGIRCDS 564
+ C C GW G C++
Sbjct: 2934 SYSCLCTLGWVGRYCEN 2950
Score = 43.1 bits (100), Expect = 0.001
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 13/73 (17%)
Query: 110 GRCVSPDT---CHCEPGWGGPDCS---SGCDSDHWGPHCSNRCQCQNGALC--NPITGAC 161
G C+ T C+C GW G C+ S CD +H PH C GA C P C
Sbjct: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTC 2677
Query: 162 VCAAGFRGWRCEE 174
C G G CE+
Sbjct: 2678 FCPLGTTGIYCEQ 2690
Score = 42.4 bits (98), Expect = 0.002
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 15/89 (16%)
Query: 448 SICSCNNGGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPID 505
S+ C NGGTC S C C GW+G CT T + C+ GA C +
Sbjct: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETV--STCDPEHDPPHHCSRGATCISLP 2672
Query: 506 GSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
+C CP GT G+ C +
Sbjct: 2673 HGYTCF-----------CPLGTTGIYCEQ 2690
Score = 41.6 bits (96), Expect = 0.004
Identities = 29/95 (30%), Positives = 39/95 (41%), Gaps = 20/95 (21%)
Query: 307 FGSFGFQCSQHCD--------CHNGGQCSP--TTGACECEPGYKGPRCQERL-CPEGLHG 355
FG+ G CD C NGG+C+ TT +C C P + G C + + C L
Sbjct: 2863 FGAKGGSNVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL-- 2920
Query: 356 PGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC 390
C C D + S +C C GW G +C
Sbjct: 2921 --CLHQSLCIPDQSFSY-----SCLCTLGWVGRYC 2948
Score = 41.6 bits (96), Expect = 0.004
Identities = 25/84 (29%), Positives = 35/84 (41%), Gaps = 13/84 (15%)
Query: 234 CQNGGTC--HHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC---DHVTG 288
C+NGG C + T C C P W G C Q +C + C H C +
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFSY 2935
Query: 289 QCHCTAGYMGDRCQEECPFGSFGF 312
C CT G++G C+ + F + F
Sbjct: 2936 SCLCTLGWVGRYCENKTSFSTAKF 2959
Score = 40.4 bits (93), Expect = 0.009
Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 10/88 (11%)
Query: 703 GPACFHACSCHNGASCSAEDG--ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS 760
G AC + +C NG C+ +C C P W G C Q +C Q+
Sbjct: 2876 GTACGYN-TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC------LNNLCLHQSLCI 2928
Query: 761 CDH-ISGKCTCRTGFTGQHCEQRCAPGT 787
D S C C G+ G++CE + + T
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYCENKTSFST 2956
Score = 38.9 bits (89), Expect = 0.026
Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 11/82 (13%)
Query: 320 CHNGGQC--SPTTGACECEPGYKGPRCQERLC---PEGLHGPGCTLPCPCDADNTISCHP 374
C NGG C S T+ C C G+KG C E + PE H P P C T P
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPE--HDP----PHHCSRGATCISLP 2672
Query: 375 VTGACTCQPGWSGHHCNESCPV 396
C C G +G +C ++ +
Sbjct: 2673 HGYTCFCPLGTTGIYCEQALSI 2694
Score = 38.1 bits (87), Expect = 0.044
Identities = 24/76 (31%), Positives = 30/76 (39%), Gaps = 17/76 (22%)
Query: 408 TCQNGADC--HSITGGCTCAPGFMGEVC--AVSCAAGTYGPNCSSICSCNNGGTCSPVDG 463
TC+NG +C + T C C P + G C +VSC C + C P
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL----------CLHQSLCIPDQS 2932
Query: 464 ---SCTCKEGWQGLDC 476
SC C GW G C
Sbjct: 2933 FSYSCLCTLGWVGRYC 2948
Score = 37.7 bits (86), Expect = 0.057
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 17/102 (16%)
Query: 224 HGAHCELRCPCQNGGTCHH--ITGECACPPGWTGAVCAQ---PCPPGTFGQNCSQDCP-- 276
H + C L C NGGTC + C C GW G+ C + C P D P
Sbjct: 2610 HASPCSLM-KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP-------EHDPPHH 2661
Query: 277 CHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQCSQ 316
C G C + C C G G C++ F+ ++
Sbjct: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSNE 2703
Score = 37.7 bits (86), Expect = 0.057
Identities = 27/99 (27%), Positives = 39/99 (39%), Gaps = 22/99 (22%)
Query: 406 PCT---CQNGADCHSITGG----CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC 458
PC+ C NG C I G C C G+ G C + + T P C+ G TC
Sbjct: 2613 PCSLMKCGNGGTC--IESGTSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATC 2668
Query: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCAN 497
+ TC CP GT G+ C ++ + ++
Sbjct: 2669 ISLPHGYTCF-----------CPLGTTGIYCEQALSISD 2696
Score = 37.7 bits (86), Expect = 0.057
Identities = 24/76 (31%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 754 QCQNGASC--DHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG-- 809
+C NG +C S C C TG+ G C + + T C +TC +
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATCISLPHGY 2675
Query: 810 TCYCSPGFKGIRCDQA 825
TC+C G GI C+QA
Sbjct: 2676 TCFCPLGTTGIYCEQA 2691
Score = 36.2 bits (82), Expect = 0.17
Identities = 28/101 (27%), Positives = 34/101 (33%), Gaps = 14/101 (13%)
Query: 354 HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGA 413
H C+L C T + C C GW G C E+ V P C GA
Sbjct: 2610 HASPCSL-MKCGNGGTCIESGTSVYCNCTTGWKGSFCTET--VSTCDPEHDPPHHCSRGA 2666
Query: 414 DCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNN 454
C S+ G TC C GT G C S ++
Sbjct: 2667 TCISLPHGYTC-----------FCPLGTTGIYCEQALSISD 2696
Score = 35.0 bits (79), Expect = 0.37
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 11/58 (18%)
Query: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP---IDGSCQCFPGWIGKDC 693
C CLP ++G CNQ C C + C P SC C GW+G+ C
Sbjct: 2899 CRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 34.7 bits (78), Expect = 0.48
Identities = 26/85 (30%), Positives = 30/85 (35%), Gaps = 18/85 (21%)
Query: 314 CSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTIS 371
C+ H C N G C CEC Y G CQ C G G T
Sbjct: 2339 CAHHL-CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGAT------------ 2385
Query: 372 CHPVTG---ACTCQPGWSGHHCNES 393
C P +G C C G SG C ++
Sbjct: 2386 CVPKSGTDIVCLCPYGRSGPLCTDA 2410
Score = 34.7 bits (78), Expect = 0.48
Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 10/75 (13%)
Query: 495 CANGAACSPIDGS--CSCTPGWLGDTCELPC----PDGTFGLNCSEHCDCSHADGCDPVT 548
C NG C S C+CT GW G C P+ +CS C P
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISL----PHG 2674
Query: 549 GHCCCLAGWTGIRCD 563
C C G TGI C+
Sbjct: 2675 YTCFCPLGTTGIYCE 2689
Score = 34.7 bits (78), Expect = 0.48
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 13/74 (17%)
Query: 148 CQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAG--- 202
C+NG C N T +C C + G C + + C L C H + C P
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-------C-LNNLCLHQSLCIPDQSFSY 2935
Query: 203 ECLCAPGYTGVYCE 216
CLC G+ G YCE
Sbjct: 2936 SCLCTLGWVGRYCE 2949
Score = 34.3 bits (77), Expect = 0.63
Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 13/72 (18%)
Query: 550 HCCCLAGWTGIRCD---STCPPGRWGPNCSVSCSCENGGSC--SPEDGSCECAPGFRGPL 604
+C C GW G C STC P P+ C G +C P +C C G G
Sbjct: 2633 YCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTCFCPLGTTGIY 2687
Query: 605 CQR---ICPPGF 613
C++ I P F
Sbjct: 2688 CEQALSISDPSF 2699
Score = 34.3 bits (77), Expect = 0.63
Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 5/70 (7%)
Query: 364 CDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCT 423
C + + T +C C P W+G+ CN+S V + C C S + C
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQS--VSCLNNLCLHQSLC---IPDQSFSYSCL 2938
Query: 424 CAPGFMGEVC 433
C G++G C
Sbjct: 2939 CTLGWVGRYC 2948
Score = 33.9 bits (76), Expect = 0.82
Identities = 31/107 (28%), Positives = 37/107 (34%), Gaps = 17/107 (15%)
Query: 569 GRWGPNCSVS-CS---CENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPL 624
GR C S CS C NGG+C S C C G+ G C +
Sbjct: 2603 GRSVGQCHASPCSLMKCGNGGTCIESGTSVYCN-----------CTTGWKGSFCTETVST 2651
Query: 625 CVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCAN 671
C P HH S C+ G C C G G C Q S ++
Sbjct: 2652 CDPEHDPPHHCSRGATCISLPHGYTC--FCPLGTTGIYCEQALSISD 2696
Score = 33.5 bits (75), Expect = 1.1
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 12/73 (16%)
Query: 553 CLAGWTGIRCDSTCPPGRWGPNCS-VSCS---CENGGSCSPEDGS---CECAPGFRGPLC 605
C++ + C+ CP G C SC C NG +C P+ G+ C C G GPLC
Sbjct: 2350 CISDNENLFCE--CPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
Query: 606 Q---RICPPGFYG 615
I P F G
Sbjct: 2408 TDAINITQPRFSG 2420
Score = 33.1 bits (74), Expect = 1.4
Identities = 25/80 (31%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 757 NGASCDHIS-GKCTCRTG----FTGQHCEQRCAPGTFGYGCQQLCECMNN-----STC-- 804
N CD + G TCR G G RC P G C Q C+NN S C
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIP 2929
Query: 805 -DHVTGTCYCSPGFKGIRCD 823
+ +C C+ G+ G C+
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCE 2949
Score = 33.1 bits (74), Expect = 1.4
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 13/75 (17%)
Query: 580 SCENGGSCSPEDG--SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSR--PCHHI 635
+C NGG C+ SC C P + G C + C LC+H S P
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLN--NLCLHQSLCIPDQSF 2933
Query: 636 SGICECLPGFSGALC 650
S C C G+ G C
Sbjct: 2934 SYSCLCTLGWVGRYC 2948
Score = 32.7 bits (73), Expect = 1.8
Identities = 23/73 (31%), Positives = 29/73 (39%), Gaps = 14/73 (19%)
Query: 452 CNNGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGS-- 507
C N GTC + + C C + G C +C E+ C NGA C P G+
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFA--------SC-ENNPCGNGATCVPKSGTDI 2394
Query: 508 -CSCTPGWLGDTC 519
C C G G C
Sbjct: 2395 VCLCPYGRSGPLC 2407
Score = 32.7 bits (73), Expect = 1.8
Identities = 18/60 (30%), Positives = 26/60 (43%), Gaps = 11/60 (18%)
Query: 117 TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNP---ITGACVCAAGFRGWRCE 173
+C C P W G C+ C N C + +LC P + +C+C G+ G CE
Sbjct: 2898 SCRCLPDWAGNTCNQSVS-------CLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 31.6 bits (70), Expect = 4.1
Identities = 14/32 (43%), Positives = 17/32 (53%), Gaps = 7/32 (21%)
Query: 234 CQNGGTCHHI-------TGECACPPGWTGAVC 258
C NGGTCH I + +C CP +TG C
Sbjct: 2108 CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
Score = 30.8 bits (68), Expect = 7.0
Identities = 25/85 (29%), Positives = 36/85 (42%), Gaps = 19/85 (22%)
Query: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLP-CQ---CRHGA 195
P C++ C+N C C C L + GK CQ C+ C +GA
Sbjct: 2337 PWCAHHL-CRNNGTCISDNENLFC-------ECPRLYS----GKLCQFASCENNPCGNGA 2384
Query: 196 SCDPRAGE---CLCAPGYTGVYCEE 217
+C P++G CLC G +G C +
Sbjct: 2385 TCVPKSGTDIVCLCPYGRSGPLCTD 2409
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 177 bits (448), Expect = 6e-44
Identities = 129/410 (31%), Positives = 172/410 (41%), Gaps = 75/410 (18%)
Query: 482 SGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS--EHCDCS 539
+G CN + ++ C+P G C C PG +G C+L C G +G + + C CS
Sbjct: 778 NGALPCQCNPQGSLSS--ECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCS 834
Query: 540 HADG----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCE-NGGSCSPEDGS 593
H C+ +G C C G G+RCD C G+WG P+C C C + C+ G+
Sbjct: 835 HEGALSSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCR-PCVCNGHADECNTHTGA 892
Query: 594 C-ECAPGFRGPLCQRICPPGFYGH------GCAQPCPLCV------HSSRPCHHISG--- 637
C C G C+R C GF+G G +PCP H + CH
Sbjct: 893 CLGCRDHTGGEHCER-CIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQ 951
Query: 638 -ICECLPGFSGALCNQVCAGGYFGQDC-----AQLCSCANN------GTCSPIDGSC-QC 684
+C C G++G C + CA G+FG QLC C+ N C P G C +C
Sbjct: 952 IVCHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRC 1010
Query: 685 FPGWIGKDCSQACPPGFWGPAC---FHACSCH------------NGASCSAEDGACHCTP 729
G C+ C PGF G A H C+C+ + C G C C P
Sbjct: 1011 LHHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLP 1069
Query: 730 GWTGLFCTQRCPAAFFGKDCGRVCQ---CQ----NGASCDHISGKCTCRTGFTGQHCE-- 780
G C RC F+ G CQ C G +C+ +G+C CR GF G+ C
Sbjct: 1070 NVQGPSC-DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128
Query: 781 QRCAPGTFGYGCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
Q G G C C+C ++ C TG C C PG G+RCDQ A
Sbjct: 1129 QELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA 1177
Score = 168 bits (426), Expect = 2e-41
Identities = 134/412 (32%), Positives = 168/412 (40%), Gaps = 81/412 (19%)
Query: 146 CQCQ-NGAL---CNPITGACVCAAGFRGWRCEELCAPGTHG---KGCQLPCQCRH----G 194
CQC G+L CNP G C+C G G RC +LCAPG +G GCQ CQC H
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQ-ACQCSHEGALS 840
Query: 195 ASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ-NGGTCHHITGECACPPGW 253
+ C+ +G+CLC G G+ C+ C G G C C + C+ TG C
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
Query: 254 TGAVCAQPCPPG-------TFGQNCSQDCPC--------HHGGQC--DHVTGQ--CHCTA 294
TG + C G +G C + CPC H C D + Q CHC A
Sbjct: 900 TGGEHCERCIAGFHGDPRLPYGGQC-RPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 295 GYMGDRCQEECPFGSFG-----------FQCSQHCDCHNGGQCSPTTGAC-ECEPGYKGP 342
GY G RC E C G FG +CS + D + C P TG C C +GP
Sbjct: 959 GYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
Query: 343 RCQERLCPEGLHGPGC-------------TLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
C C G HG T P C + + C P +G C C P G
Sbjct: 1018 HCAH--CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
Query: 390 CNESCPVGY---YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAA--- 439
C+ P + G GCQ PC C G C+ TG C C GF G C+ C
Sbjct: 1076 CDRCAPNFWNLTSGHGCQ-PCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHW 1133
Query: 440 GTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGL 487
G G C + C C++ G C G C+C+ G G+ C C G G+
Sbjct: 1134 GDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD-QCARGFSGI 1183
Score = 164 bits (415), Expect = 4e-40
Identities = 139/454 (30%), Positives = 172/454 (37%), Gaps = 100/454 (22%)
Query: 187 LPCQCRHGAS----CDPRAGECLCAPGYTGVYCEELCPPGSHG---AHCELRCPCQNGGT 239
LPCQC S C+P G+CLC PG G C +LC PG +G C+ C C + G
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQ-ACQCSHEGA 838
Query: 240 ----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCH-HGGQCDHVTGQCHCTA 294
C +G+C C G G C + C G +G + C C+ H +C+ TG C
Sbjct: 839 LSSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCR 897
Query: 295 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH 354
+ G E C G G + GGQC P C C G R C +
Sbjct: 898 DHTGGEHCERCIAGFHGDPRLPY-----GGQCRP----CPCPEGPGSQRHFATSCHQD-- 946
Query: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGD------GCQLPCT 408
+ I CH C+ G++G C E+C G++GD CQL C
Sbjct: 947 ----------EYSQQIVCH-------CRAGYTGLRC-EACAPGHFGDPSRPGGRCQL-CE 987
Query: 409 CQNGAD------CHSITGGCT-------------CAPGFMGEVCAVSC------AAGTYG 443
C D C TG C C PGF G+ SC GT
Sbjct: 988 CSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNP 1047
Query: 444 PNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCN---ESCTC----A 496
C S C+ C P G C C QG C C W L + C C A
Sbjct: 1048 QQCPSPDQCH----CDPSSGQCPCLPNVQGPSCD-RCAPNFWNLTSGHGCQPCACHPSRA 1102
Query: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPD---GTFGLNCSEHCDCS----HADGCDPVTG 549
G C+ G C C G+ G TC C + G GL C CDC C TG
Sbjct: 1103 RGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTG 1160
Query: 550 HCCCLAGWTGIRCDSTCPPGRWG--PNCSVSCSC 581
HC C G +G+RCD C G G P C +C
Sbjct: 1161 HCSCRPGVSGVRCDQ-CARGFSGIFPACHPCHAC 1193
Score = 152 bits (383), Expect = 2e-36
Identities = 127/411 (30%), Positives = 157/411 (38%), Gaps = 79/411 (19%)
Query: 318 CDCHNGG----QCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCT--LPCPCDADNTIS 371
C C+ G +C+P G C C+PG G RC LC G +G G T C C + +S
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCD--LCAPGYYGFGPTGCQACQCSHEGALS 840
Query: 372 --CHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD-CHSITGGCT-CAPG 427
C +G C C+ G G C+ C G +G PC C AD C++ TG C C
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
Query: 428 FMGEVCAVSCAAG-------TYGPNCSSICSCNNGG--------TCSPVDGS----CTCK 468
GE C C AG YG C C C G +C + S C C+
Sbjct: 900 TGGEHCE-RCIAGFHGDPRLPYGGQCRP-CPCPEGPGSQRHFATSCHQDEYSQQIVCHCR 957
Query: 469 EGWQGLDCTLPCPSGTWGLNCN-----ESCTCANGA------ACSPIDGSC--------- 508
G+ GL C C G +G + C C+ AC P G C
Sbjct: 958 AGYTGLRCEA-CAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
Query: 509 ----SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGC--DPVTGHCCCLAGWTGIRC 562
C PG+ G C T L + C D C DP +G C CL G C
Sbjct: 1017 PHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSC 1076
Query: 563 DSTCPPGRW----GPNCSVSCSCE----NGGSCSPEDGSCECAPGFRGPLCQRICP---- 610
D C P W G C C+C G +C+ G C C GF G C
Sbjct: 1077 DR-CAPNFWNLTSGHGCQ-PCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG 1134
Query: 611 -PGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFG 660
PG H C C + CH +G C C PG SG C+Q CA G+ G
Sbjct: 1135 DPGLQCHAC--DCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSG 1182
Score = 141 bits (356), Expect = 3e-33
Identities = 127/385 (32%), Positives = 145/385 (37%), Gaps = 80/385 (20%)
Query: 83 RRRSQCCPGYYESGDFCIPLCTEECVHGRCVS------PDTCHCEPGWGGPDCSSGCDSD 136
RR C PGYY G C +C H +S C C G G C C
Sbjct: 811 RRCDLCAPGYYGFGPTGCQAC--QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDR-CQRG 867
Query: 137 HWGPHCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPGTHGK------GCQLPC 189
WG C C A CN TGAC+ G E C G HG G PC
Sbjct: 868 QWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPC 927
Query: 190 QCRHG--------ASC--DPRAGE--CLCAPGYTGVYCEELCP-----PGSHGAHCELRC 232
C G SC D + + C C GYTG+ CE P P G C+L C
Sbjct: 928 PCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQL-C 986
Query: 233 PCQNG-------------GTC----HHITG-ECA-CPPGWTGAVCAQPCPP------GTF 267
C G C HH G CA C PG+ G Q C GT
Sbjct: 987 ECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTN 1046
Query: 268 GQNCSQDCPCHHGGQCDHVTGQCHCTAGYMG---DRCQEECPFGSFGFQCSQHCDCH--- 321
Q C CH CD +GQC C G DRC + G C Q C CH
Sbjct: 1047 PQQCPSPDQCH----CDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC-QPCACHPSR 1101
Query: 322 -NGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC-PCDAD----NTISCHPV 375
G C+ TG C C G+ G C E C E LH L C CD D +T CH
Sbjct: 1102 ARGPTCNEFTGQCHCRAGFGGRTCSE--CQE-LHWGDPGLQCHACDCDSRGIDTPQCHRF 1158
Query: 376 TGACTCQPGWSGHHCNESCPVGYYG 400
TG C+C+PG SG C++ C G+ G
Sbjct: 1159 TGHCSCRPGVSGVRCDQ-CARGFSG 1182
Score = 89.7 bits (221), Expect = 1e-17
Identities = 77/239 (32%), Positives = 96/239 (40%), Gaps = 35/239 (14%)
Query: 97 DFCIPLCTEECVHGRCV----SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQC--QN 150
D C P T +C+ RC+ P HC+PG+ G C +N QC +
Sbjct: 998 DACDPH-TGQCL--RCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPD 1054
Query: 151 GALCNPITGACVCAAGFRGWRCEELCAPG----THGKGCQLPCQCR----HGASCDPRAG 202
C+P +G C C +G C+ CAP T G GCQ PC C G +C+ G
Sbjct: 1055 QCHCDPSSGQCPCLPNVQGPSCDR-CAPNFWNLTSGHGCQ-PCACHPSRARGPTCNEFTG 1112
Query: 203 ECLCAPGYTGVYCEELCPP---GSHGAHCELRCPCQNGG----TCHHITGECACPPGWTG 255
+C C G+ G C E C G G C C C + G CH TG C+C PG +G
Sbjct: 1113 QCHCRAGFGGRTCSE-CQELHWGDPGLQCH-ACDCDSRGIDTPQCHRFTGHCSCRPGVSG 1170
Query: 256 AVCAQPCPPGTFG--QNCSQDCPCHH-GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG 311
C Q C G G C PCH G D V + R QE G G
Sbjct: 1171 VRCDQ-CARGFSGIFPACH---PCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLG 1225
Score = 85.5 bits (210), Expect = 2e-16
Identities = 74/272 (27%), Positives = 97/272 (35%), Gaps = 46/272 (16%)
Query: 157 ITGACVCAAGFRGWRCEELC----------APGTHGKGCQLPCQCR-HGASCDPRAGECL 205
+ GAC+C RG CE+ A H C+ C+C H SC L
Sbjct: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR-KCECHGHTHSCHFDMAVYL 364
Query: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265
+ +G C+ C + G HCEL P + C + C
Sbjct: 365 ASGNVSGGVCDG-CQHNTAGRHCELCRPFFYRDPTKDLRDPAVC----------RSCDCD 413
Query: 266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS-----QHCDC 320
G C H V+GQC C +G RCQ+ C G FG S + C C
Sbjct: 414 PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQC 472
Query: 321 HNGGQ------CSPTTGACECEPGYKGPRCQERLCPEGLHGP-----GCTLPCPCDADNT 369
+ G C P +G+C C+ G C C G G GC PC CD
Sbjct: 473 NARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR--CLPGHWGLSHDLLGCR-PCDCDVGGA 529
Query: 370 IS--CHPVTGACTCQPGWSGHHCNESCPVGYY 399
+ C TG C C+ G C + P GY+
Sbjct: 530 LDPQCDEGTGQCHCRQHMVGRRCEQVQP-GYF 560
Score = 76.3 bits (186), Expect = 1e-13
Identities = 72/270 (26%), Positives = 94/270 (34%), Gaps = 45/270 (16%)
Query: 375 VTGACTCQPGWSGHHCNESCPVGYYG-------DGCQLPCTCQNGADCHSITGGCTCAPG 427
V GAC C+ G +C E C Y DG C +CH T C
Sbjct: 306 VHGACICKHNTRGLNC-EQCQDFYRDLPWRPAEDGHSHAC---RKCECHGHTHSCHFD-- 359
Query: 428 FMGEVCAVSCAAGTYGPNCSSICSCNNGGT----CSPVDGSCTCKEGWQGLDCTLPCPSG 483
AV A+G C N G C P K+ C C
Sbjct: 360 -----MAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCR-SCDCD 413
Query: 484 TWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD- 542
G C + A + G C C +G C+ C DG FGL+ S+ C
Sbjct: 414 PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRRCQC 472
Query: 543 ----------GCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV----SCSCENGGSCS 588
CDP +G C C TG CD C PG WG + + C C+ GG+
Sbjct: 473 NARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALD 531
Query: 589 PE----DGSCECAPGFRGPLCQRICPPGFY 614
P+ G C C G C+++ PG++
Sbjct: 532 PQCDEGTGQCHCRQHMVGRRCEQV-QPGYF 560
Score = 75.5 bits (184), Expect = 2e-13
Identities = 67/261 (25%), Positives = 96/261 (36%), Gaps = 45/261 (17%)
Query: 202 GECLCAPGYTGVYCEELCP--------PGSHG-AHCELRCPCQ-NGGTCHHITGECACPP 251
G C+C G+ CE+ P G +H +C C + +CH
Sbjct: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
Query: 252 GWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG 311
+G VC C T G++C P + + C + C G
Sbjct: 368 NVSGGVC-DGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRS----------CDCDPMG 416
Query: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG------PGCTLPCPCD 365
Q CD H+ +G C C+ G RCQ+ C +G G GC C C+
Sbjct: 417 SQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ--CRDGFFGLSISDRLGCR-RCQCN 473
Query: 366 ADNTI----SCHPVTGACTCQPGWSGHHCNESCPVGYYG-----DGCQLPCTCQNGA--- 413
A T+ C P +G+C C+ +G C+ P G++G GC+ PC C G
Sbjct: 474 ARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLP-GHWGLSHDLLGCR-PCDCDVGGALD 531
Query: 414 -DCHSITGGCTCAPGFMGEVC 433
C TG C C +G C
Sbjct: 532 PQCDEGTGQCHCRQHMVGRRC 552
Score = 73.9 bits (180), Expect = 7e-13
Identities = 76/289 (26%), Positives = 100/289 (34%), Gaps = 64/289 (22%)
Query: 585 GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP--CHHISGICECL 642
G+C + ECAP P + G +C H++R C L
Sbjct: 281 GNCFCYGHASECAPAPGAPA---------HAEGMVHGACICKHNTRGLNCEQCQDFYRDL 331
Query: 643 P------GFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQA 696
P G S A C G A+ + CQ G+ C +
Sbjct: 332 PWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQ--HNTAGRHC-EL 388
Query: 697 CPPGFW--------GPACFHACSC-----HNGASCSAED--------GACHCTPGWTGLF 735
C P F+ PA +C C +G C + D G C C G
Sbjct: 389 CRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTR 448
Query: 736 CTQRCPAAFFGKDCG-----RVCQCQ------NGASCDHISGKCTCRTGFTGQHCEQRCA 784
C Q+C FFG R CQC CD SG C C+ TG+ C+ RC
Sbjct: 449 C-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-RCL 506
Query: 785 PGTFGY-----GCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
PG +G GC+ C+C + CD TG C+C G RC+Q
Sbjct: 507 PGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ 554
Score = 72.4 bits (176), Expect = 2e-12
Identities = 75/291 (25%), Positives = 97/291 (33%), Gaps = 73/291 (25%)
Query: 76 RGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDS 135
RG Y S+C P P E VHG C+ H G C
Sbjct: 280 RGNCFCYGHASECAPAPGA------PAHAEGMVHGACICK---HNTRGLNCEQCQDFYRD 330
Query: 136 DHWGP------HCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQL- 187
W P H +C+C C+ + + G C+ C T G+ C+L
Sbjct: 331 LPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG-CQHNTAGRHCELC 389
Query: 188 --------------PCQCRHGASCDPR-------------------AGECLCAPGYTGVY 214
P CR CDP +G+C C G
Sbjct: 390 RPFFYRDPTKDLRDPAVCR-SCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTR 448
Query: 215 CEELCPPGSHGAHCE-----LRCPCQNGGT------CHHITGECACPPGWTGAVCAQPCP 263
C++ C G G RC C GT C +G C C TG C + C
Sbjct: 449 CQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CL 506
Query: 264 PGTFGQNCS----QDCPCHHGG----QCDHVTGQCHCTAGYMGDRCQEECP 306
PG +G + + C C GG QCD TGQCHC +G RC++ P
Sbjct: 507 PGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
Score = 61.6 bits (148), Expect = 4e-09
Identities = 78/321 (24%), Positives = 108/321 (33%), Gaps = 66/321 (20%)
Query: 492 SCTCANGAA-CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD----GCDP 546
+C C A+ C+P G+ + G + C C T GLNC E C + D +
Sbjct: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACI--CKHNTRGLNC-EQCQDFYRDLPWRPAED 338
Query: 547 VTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFRGPLCQ 606
H C C + ++ +GG C DG C G C+
Sbjct: 339 GHSHAC-----RKCECHGHTHSCHFDMAVYLASGNVSGGVC---DG---CQHNTAGRHCE 387
Query: 607 RICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQL 666
+C P FY V S C+C P G
Sbjct: 388 -LCRPFFYRDPTKDLRDPAVCRS---------CDCDP---------------MGSQDGGR 422
Query: 667 CSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACF-----HACSCH------NG 715
C ++ + G C+C +G C Q C GF+G + C C+
Sbjct: 423 CDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGS 481
Query: 716 ASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCG----RVCQCQNGAS----CDHISGK 767
C G+C+C TG C RC +G R C C G + CD +G+
Sbjct: 482 TPCDPNSGSCYCKRLVTGRGC-DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ 540
Query: 768 CTCRTGFTGQHCEQRCAPGTF 788
C CR G+ CEQ PG F
Sbjct: 541 CHCRQHMVGRRCEQ-VQPGYF 560
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 172 bits (436), Expect = 1e-42
Identities = 141/424 (33%), Positives = 172/424 (40%), Gaps = 84/424 (19%)
Query: 230 LRCPCQNGGT----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCS--QDCPCHHGGQ- 282
L C C G+ C G+C C P G C + C PGTFG S + C CH G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSV 829
Query: 283 ---CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCH-NGGQCSPTTGAC-ECEP 337
C+ VTGQCHC G +C + C G +GF Q C C+ + C P TG C C+
Sbjct: 830 NAFCNPVTGQCHCFQGVYARQC-DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQD 888
Query: 338 GYKGPRCQERLCPEGLHGPGCT------LPCPC----DADNTI--SCH--PVTG--ACTC 381
G C+ C G +G PCPC D+ SC+ PVT AC C
Sbjct: 889 YTMGHNCER--CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
Query: 382 QPGWSGHHCNESCPVGYYGD------GCQLPCTCQNGAD------CHSITGGCT-CAPGF 428
PG+ G C++ C GY+G+ CQ PC C N D C TG C C
Sbjct: 947 DPGYIGSRCDD-CASGYFGNPSEVGGSCQ-PCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
Query: 429 MGEVCAVSCAAGTYGP----NCSSICSCNNGGT-----------CSPVDGSCTCKEGWQG 473
GE C C G YG +C C CN GT C G C C G
Sbjct: 1005 EGEHCQF-CRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 474 LDCTLPCPSGTWGLNCNESCTCAN-------GAACSPIDGSCSCTPGWLGDTCELPCPDG 526
+C C TW L C N G +C+ G C C PG+ G TC C +
Sbjct: 1063 QNCDR-CAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQEL 1120
Query: 527 TFG---LNCSEHCDCS----HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG--PNCSV 577
+G + C CDC CD TG C C+ G G RCD C G G P+C+
Sbjct: 1121 FWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSGVFPDCTP 1178
Query: 578 SCSC 581
C
Sbjct: 1179 CHQC 1182
Score = 161 bits (408), Expect = 3e-39
Identities = 127/403 (31%), Positives = 161/403 (39%), Gaps = 80/403 (19%)
Query: 118 CHCEPGWGGPDCSSGCDSDH-WGPHCSNRCQCQN----GALCNPITGACVCAAGFRGWRC 172
C C P G C+ +GP C+C A CNP+TG C C G +C
Sbjct: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
Query: 173 EELCAPGTHGKGCQLPCQCR-HGASCDPRAGECLCAPGYTGVYCEELCPPGSH------- 224
+ C PG G PCQC H CDP GECL YT + E C G +
Sbjct: 852 DR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGS 910
Query: 225 GAHCELRCPCQNG--------GTCHH----ITGECACPPGWTGAVCAQPCPPGTFGQ--- 269
G HC CPC +G +C+ + C C PG+ G+ C C G FG
Sbjct: 911 GDHCR-PCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSE 968
Query: 270 --NCSQDCPCHHG------GQCDHVTGQC-------------HCTAGYMGDRCQEECP-- 306
Q C CH+ CD TG+C C GY GD Q++C
Sbjct: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQQDCRKC 1028
Query: 307 FGSFGFQCSQHC---DCHNGGQCSPTTGACECEPGYKGPRCQERLCP---EGLHGPGCTL 360
++ +HC DC QC TG C C P G C +R P + G GC
Sbjct: 1029 VCNYLGTVQEHCNGSDC----QCDKATGQCLCLPNVIGQNC-DRCAPNTWQLASGTGCD- 1082
Query: 361 PCPCDADNTI--SCHPVTGACTCQPGWSGHHCNESCPVGYYGD---GCQLPCTCQ----N 411
PC C+A ++ SC+ TG C C PG+ G C+E C ++GD C+ C C
Sbjct: 1083 PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVECR-ACDCDPRGIE 1140
Query: 412 GADCHSITGGCTCAPGFMGEVCAVSCAAGTYG--PNCSSICSC 452
C TG C C G G C C G G P+C+ C
Sbjct: 1141 TPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGVFPDCTPCHQC 1182
Score = 161 bits (407), Expect = 3e-39
Identities = 153/479 (31%), Positives = 184/479 (38%), Gaps = 106/479 (22%)
Query: 353 LHGPGCTLPCPCDADNTIS--CHPVTGACTCQPGWSGHHCNESCP--VGYYGDGCQLPCT 408
LH G L C CD ++S C P G C C+P G CN P G+ GC+ PC
Sbjct: 766 LHQTG--LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCK-PCE 822
Query: 409 C----QNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-PNCSSICSCN-NGGTCSPVD 462
C A C+ +TG C C G C C G +G P+C C CN + C PV
Sbjct: 823 CHLQGSVNAFCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQP-CQCNGHADDCDPVT 880
Query: 463 GSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE-L 521
G C L C T G NC C G PI GS GD C
Sbjct: 881 GEC------------LNCQDYTMGHNCER---CLAGYYGDPIIGS--------GDHCRPC 917
Query: 522 PCPDG-----TFGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCDSTCPPGRWGPN 574
PCPDG F +C + DPVT C C G+ G RCD C G +G
Sbjct: 918 PCPDGPDSGRQFARSCYQ----------DPVTLQLACVCDPGYIGSRCDD-CASGYFGNP 966
Query: 575 CSVS-----CSCENG------GSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCAQPC 622
V C C N +C E G C +C G CQ C G+YG Q C
Sbjct: 967 SEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ-FCRFGYYGDALQQDC 1025
Query: 623 PLCV------------HSSRPCHHISGICECLPGFSGALCNQVCAGGYF----GQDCAQL 666
CV S C +G C CLP G C++ CA + G C
Sbjct: 1026 RKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR-CAPNTWQLASGTGC-DP 1083
Query: 667 CSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGP---ACFHACSCH----NG 715
C+C + +C+ G CQC PG+ G+ CS+ C FWG C AC C
Sbjct: 1084 CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVEC-RACDCDPRGIET 1141
Query: 716 ASCSAEDGACHCTPGWTGLFCTQRCPAAFFG--KDCGRVCQCQNGASCDHISGKCTCRT 772
C G C C G G C +C + G DC QC A D I + T RT
Sbjct: 1142 PQCDQSTGQCVCVEGVEGPRC-DKCTRGYSGVFPDCTPCHQC--FALWDVIIAELTNRT 1197
Score = 160 bits (406), Expect = 4e-39
Identities = 135/429 (31%), Positives = 171/429 (39%), Gaps = 82/429 (19%)
Query: 182 GKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHG---AHCELRCPCQNGG 238
G C+ Q + CDP G+C C P G C C PG+ G + C+ C C G
Sbjct: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCK-PCECHLQG 827
Query: 239 T----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCH-HGGQCDHVTGQC-HC 292
+ C+ +TG+C C G C + C PG +G Q C C+ H CD VTG+C +C
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNC 886
Query: 293 TAGYMGDRCQEECPFGSFG---FQCSQH---CDCHNGGQC----------SPTT--GACE 334
MG C E C G +G H C C +G P T AC
Sbjct: 887 QDYTMGHNC-ERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
Query: 335 CEPGYKGPRCQERLCPEGLHG-----PGCTLPCPC----DADNTISCHPVTGAC-TCQPG 384
C+PGY G RC + C G G G PC C D + +C TG C C
Sbjct: 946 CDPGYIGSRCDD--CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 385 WSGHHCNESCPVGYYGDGCQ---LPCTCQ---------NGADCH--SITGGCTCAPGFMG 430
G HC + C GYYGD Q C C NG+DC TG C C P +G
Sbjct: 1004 TEGEHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 431 EVCAVSCAAGTY----GPNCSSICSCNN----GGTCSPVDGSCTCKEGWQGLDCTLPCPS 482
+ C CA T+ G C C+CN G +C+ G C C G+ G C+ C
Sbjct: 1063 QNCD-RCAPNTWQLASGTGCDP-CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQE 1119
Query: 483 GTWG---LNCNESCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEH 535
WG + C +C C C G C C G G C+ C G G+
Sbjct: 1120 LFWGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGV----F 1173
Query: 536 CDCSHADGC 544
DC+ C
Sbjct: 1174 PDCTPCHQC 1182
Score = 157 bits (398), Expect = 4e-38
Identities = 130/404 (32%), Positives = 165/404 (40%), Gaps = 74/404 (18%)
Query: 486 GLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS--EHCDCSHADG 543
GL C + + C P G C C P +G TC C GTFG S + C+C H G
Sbjct: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCEC-HLQG 827
Query: 544 -----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCE-NGGSCSPEDGSC-E 595
C+PVTG C C G +CD C PG WG P+C C C + C P G C
Sbjct: 828 SVNAFCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQ-PCQCNGHADDCDPVTGECLN 885
Query: 596 CAPGFRGPLCQRICPPGFYG--------HGCAQPCPLCVHS----SRPCHH----ISGIC 639
C G C+R C G+YG H PCP S +R C+ + C
Sbjct: 886 CQDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLAC 944
Query: 640 ECLPGFSGALCNQVCAGGYFGQ-----DCAQLCSCANN------GTCSPIDGSC-QCFPG 687
C PG+ G+ C+ CA GYFG Q C C NN C G C +C
Sbjct: 945 VCDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 688 WIGKDCSQACPPGFWGPAC---FHACSCH---------NGASCSAE--DGACHCTPGWTG 733
G+ C Q C G++G A C C+ NG+ C + G C C P G
Sbjct: 1004 TEGEHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 734 LFCTQRCPAAF---FGKDCGRVCQCQN----GASCDHISGKCTCRTGFTGQHCE--QRCA 784
C + P + G C C C G SC+ +G+C C GF G+ C Q
Sbjct: 1063 QNCDRCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELF 1121
Query: 785 PGTFGYGCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
G C + C+C + CD TG C C G +G RCD+
Sbjct: 1122 WGDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
Score = 147 bits (371), Expect = 5e-35
Identities = 127/413 (30%), Positives = 161/413 (38%), Gaps = 84/413 (20%)
Query: 146 CQCQN----GALCNPITGACVCAAGFRGWRCEELCAPGTHG---KGCQLPCQCR----HG 194
C+C ++C+P G C C G C CAPGT G GC+ PC+C
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCK-PCECHLQGSVN 830
Query: 195 ASCDPRAGECLCAPGYTGVYCEELCPPGSHG-AHCELRCPCQNGG---TCHHITGECACP 250
A C+P G+C C G C+ C PG G C+ PCQ G C +TGEC
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQ---PCQCNGHADDCDPVTGECLNC 886
Query: 251 PGWTGAVCAQPCPPGTFGQ------NCSQDCPCHHGGQC----------DHVTGQ--CHC 292
+T + C G +G + + CPC G D VT Q C C
Sbjct: 887 QDYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
Query: 293 TAGYMGDRCQEECPFGSFGFQCS-----QHCDCHNG------GQCSPTTGAC-ECEPGYK 340
GY+G RC ++C G FG Q C CHN C TG C +C +
Sbjct: 947 DPGYIGSRC-DDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
Query: 341 GPRCQERLCPEGLHGPGC---TLPCPCDADNTI---------SCHPVTGACTCQPGWSGH 388
G CQ C G +G C C+ T+ C TG C C P G
Sbjct: 1006 GEHCQ--FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQ 1063
Query: 389 HCNESCPVGYY---GDGCQLPCTCQN----GADCHSITGGCTCAPGFMGEVCAVSCAAGT 441
+C+ P + G GC PC C G C+ TG C C PGF G C+ C
Sbjct: 1064 NCDRCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQELF 1121
Query: 442 YGP---NCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGL 487
+G C + C C+ G C G C C EG +G C C G G+
Sbjct: 1122 WGDPDVECRA-CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGV 1172
Score = 121 bits (304), Expect = 3e-27
Identities = 94/328 (28%), Positives = 132/328 (40%), Gaps = 59/328 (17%)
Query: 577 VSCSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYGHGCA--QPCPLCVHSSR 630
++C C+ GS C P G C+C P G C R C PG +G G + +PC + S
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSV 829
Query: 631 P--CHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGT-CSPIDGSC-QCFP 686
C+ ++G C C G C++ C G++G Q C C + C P+ G C C
Sbjct: 830 NAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQD 888
Query: 687 GWIGKDCSQACPPGFWGPACFHA------CSCHNGASCSAEDG------------ACHCT 728
+G +C + C G++G + C C +G + AC C
Sbjct: 889 YTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
Query: 729 PGWTGLFCTQRCPAAFFGKDCG-----RVCQCQNGA------SCDHISGKCT-CRTGFTG 776
PG+ G C C + +FG + CQC N +CD +G+C C G
Sbjct: 948 PGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEG 1006
Query: 777 QHCEQRCAPGTFGYGCQQLC-ECMNN-------------STCDHVTGTCYCSPGFKGIRC 822
+HC Q C G +G QQ C +C+ N CD TG C C P G C
Sbjct: 1007 EHC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
Query: 823 DQAALMMEELNPYTKISPALGAERHSVG 850
D+ A +L T P HS G
Sbjct: 1066 DRCAPNTWQLASGTGCDPCNCNAAHSFG 1093
Score = 79.3 bits (194), Expect = 2e-14
Identities = 72/258 (27%), Positives = 90/258 (34%), Gaps = 65/258 (25%)
Query: 202 GECLCAPGYTGVYCEELC----------PPGSHGAHCELRCPC-QNGGTCHHITGECACP 250
G C+C G+ CE LC P ++ +C C ++ +CH
Sbjct: 296 GHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLAT 354
Query: 251 PGWTGAVCAQPCPPGTFGQNCSQ--------------------DCPCHHGGQ-----CDH 285
+G VC C T G+NC Q C C G CD
Sbjct: 355 GNVSGGVC-DDCQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDS 413
Query: 286 VT--------GQCHCTAGYMGDRCQ----------EECPFGSFGFQCSQHCDCHNGGQCS 327
T GQC C G+ C E PFG C+ G C
Sbjct: 414 YTDFSTGLIAGQCRCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCD 473
Query: 328 PTTGACECEPGYKGPRCQERLCPE--GLHGP--GCTLPCPCDADNTI--SCHPVTGACTC 381
TG C C+ G C + L PE GL GC PC CD + SC +G C+C
Sbjct: 474 SETGHCYCKRLVTGQHCDQCL-PEHWGLSNDLDGCR-PCDCDLGGALNNSCFAESGQCSC 531
Query: 382 QPGWSGHHCNESCPVGYY 399
+P G CNE P GYY
Sbjct: 532 RPHMIGRQCNEVEP-GYY 548
Score = 73.2 bits (178), Expect = 1e-12
Identities = 76/242 (31%), Positives = 90/242 (37%), Gaps = 62/242 (25%)
Query: 84 RRSQCCPGYY----ESGDFCIPL-------------CTEECVHGRCVS------PDTCH- 119
R C GY+ E G C P C +E GRC+ + C
Sbjct: 954 RCDDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKET--GRCLKCLYHTEGEHCQF 1011
Query: 120 CEPGWGGP----DCSSGCDSDHWGP---HCSNRCQCQNGALCNPITGACVCAAGFRGWRC 172
C G+ G DC C ++ G HC N CQ C+ TG C+C G C
Sbjct: 1012 CRFGYYGDALQQDCRK-CVCNYLGTVQEHC-NGSDCQ----CDKATGQCLCLPNVIGQNC 1065
Query: 173 EELCAPGT----HGKGCQLPCQCR----HGASCDPRAGECLCAPGYTGVYCEELCPP--- 221
+ CAP T G GC PC C G SC+ G+C C PG+ G C E C
Sbjct: 1066 DR-CAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFW 1122
Query: 222 GSHGAHCELRCPCQNGG----TCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-P 276
G C C C G C TG+C C G G C C G G DC P
Sbjct: 1123 GDPDVECR-ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRC-DKCTRGYSG--VFPDCTP 1178
Query: 277 CH 278
CH
Sbjct: 1179 CH 1180
Score = 70.9 bits (172), Expect = 6e-12
Identities = 86/335 (25%), Positives = 112/335 (33%), Gaps = 71/335 (21%)
Query: 450 CSC-NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSC 508
C C + C+PVDG EG C C T GLNC + P +G
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM--CRHNTKGLNCELCMDFYHDLPWRPAEGRN 328
Query: 509 SCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD-----GCDPVTGHCC--CLAGWTGIR 561
S + C+ NC+EH H D V+G C C G
Sbjct: 329 S-------NACKK--------CNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRN 373
Query: 562 CDSTCP-----PGR--WGPNCSVSCSCENGGS-----CSPED--------GSCECAPGFR 601
C+ P P R PN C+C+ GS C G C C
Sbjct: 374 CEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVE 433
Query: 602 GPLCQRICPPGFYGHGCAQP--CPLC-------VHSSRPCHHISGICECLPGFSGALCNQ 652
G C +C GFY P C C + PC +G C C +G C+Q
Sbjct: 434 GEHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ 492
Query: 653 VCAGGYFGQ----DCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGP 704
C ++G D + C C A N +C G C C P IG+ C++ PG++
Sbjct: 493 -CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEV-EPGYYFA 550
Query: 705 ACFH------ACSCHNGASCSAEDGACHCTPGWTG 733
H + G S P WTG
Sbjct: 551 TLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTG 585
Score = 65.5 bits (158), Expect = 3e-10
Identities = 80/280 (28%), Positives = 99/280 (35%), Gaps = 86/280 (30%)
Query: 317 HCDCH-NGGQCSPTTGA-----------CECEPGYKGPRCQERLC-----------PEGL 353
+C C+ + +C+P G C C KG C+ LC EG
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE--LCMDFYHDLPWRPAEGR 327
Query: 354 HGPGCTLPCPCDADNTISCH-----------PVTGACT-CQPGWSGHHCNESCPVGYYG- 400
+ C C C+ +++ISCH G C CQ G +C E C YY
Sbjct: 328 NSNACK-KCNCN-EHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNC-EQCKPFYYQH 384
Query: 401 --------DGCQLPCTC-----QNGADCHSIT--------GGCTCAPGFMGEVCAVSCAA 439
+ C+ CTC QN C S T G C C GE C V C
Sbjct: 385 PERDIRDPNFCER-CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCDV-CKE 442
Query: 440 GTYGPN------CSSICSCNNGGT------CSPVDGSCTCKEGWQGLDCTLPCPSGTWGL 487
G Y + C S C+CN GT C G C CK G C C WGL
Sbjct: 443 GFYDLSSEDPFGCKS-CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD-QCLPEHWGL 500
Query: 488 NCN----ESCTCANGAA----CSPIDGSCSCTPGWLGDTC 519
+ + C C G A C G CSC P +G C
Sbjct: 501 SNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Score = 62.0 bits (149), Expect = 3e-09
Identities = 75/322 (23%), Positives = 101/322 (31%), Gaps = 81/322 (25%)
Query: 535 HCDC-SHADGCDPVTG-----------HCCCLAGWTGIRCDSTC---------PPGRWGP 573
+C C HA C PV G HC C G+ C+ P
Sbjct: 270 NCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCELCMDFYHDLPWRPAEGRNS 329
Query: 574 NCSVSCSC-ENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPC 632
N C+C E+ SC + G +C C G C Q P
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERD 388
Query: 633 HHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKD 692
CE C G +C + + I G C+C G+
Sbjct: 389 IRDPNFCER------------CTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEGEH 436
Query: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRV 752
C C GF+ + C + C C P T
Sbjct: 437 CD-VCKEGFYDLSSEDPFGCKS----------CACNPLGT-------------------- 465
Query: 753 CQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY-----GCQQLCEC-----MNNS 802
G CD +G C C+ TGQHC+Q C P +G GC+ C+C +NNS
Sbjct: 466 --IPGGNPCDSETGHCYCKRLVTGQHCDQ-CLPEHWGLSNDLDGCRP-CDCDLGGALNNS 521
Query: 803 TCDHVTGTCYCSPGFKGIRCDQ 824
C +G C C P G +C++
Sbjct: 522 -CFAESGQCSCRPHMIGRQCNE 542
Score = 56.6 bits (135), Expect = 1e-07
Identities = 50/203 (24%), Positives = 66/203 (32%), Gaps = 45/203 (22%)
Query: 80 TMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWG 139
TM R QC P YY+ H E P+ C D G
Sbjct: 369 TMGRNCEQCKPFYYQ------------------------HPERDIRDPNFCERCTCDPAG 404
Query: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRH------ 193
C I G C C G C+ +C G + + P C+
Sbjct: 405 SQNEGICDSYTDFSTGLIAGQCRCKLNVEGEHCD-VCKEGFYDLSSEDPFGCKSCACNPL 463
Query: 194 -----GASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCEL----RCPCQNGG----TC 240
G CD G C C TG +C++ C P G +L C C GG +C
Sbjct: 464 GTIPGGNPCDSETGHCYCKRLVTGQHCDQ-CLPEHWGLSNDLDGCRPCDCDLGGALNNSC 522
Query: 241 HHITGECACPPGWTGAVCAQPCP 263
+G+C+C P G C + P
Sbjct: 523 FAESGQCSCRPHMIGRQCNEVEP 545
Score = 55.1 bits (131), Expect = 3e-07
Identities = 61/266 (22%), Positives = 86/266 (32%), Gaps = 51/266 (19%)
Query: 243 ITGECACPPGWTGAVCAQPC----------PPGTFGQNCSQDCPCHHGGQCDHVTGQCHC 292
+ G C C G C + C P N + C C+ H +
Sbjct: 294 VHGHCMCRHNTKGLNC-ELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYL 352
Query: 293 TAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPR-CQERLC-P 350
G + ++C + G C Q C P E + P C+ C P
Sbjct: 353 ATGNVSGGVCDDCQHNTMGRNCEQ---------CKPFYYQ-HPERDIRDPNFCERCTCDP 402
Query: 351 EGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQ 410
G G CD+ S + G C C+ G HC + C G+Y + P C+
Sbjct: 403 AGSQNEGI-----CDSYTDFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCK 456
Query: 411 N-----------GADCHSITGGCTCAPGFMGEVCAVSCAAGTYG-----PNCSSICSCNN 454
+ G C S TG C C G+ C C +G C C C+
Sbjct: 457 SCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD-QCLPEHWGLSNDLDGCRP-CDCDL 514
Query: 455 GG----TCSPVDGSCTCKEGWQGLDC 476
GG +C G C+C+ G C
Sbjct: 515 GGALNNSCFAESGQCSCRPHMIGRQC 540
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 171 bits (432), Expect = 4e-42
Identities = 132/403 (32%), Positives = 175/403 (43%), Gaps = 76/403 (18%)
Query: 492 SCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLN------CSEHCDCSHA 541
+C C + G++CS + G C C P +G C+ C G++ L C H S
Sbjct: 768 ACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKD 826
Query: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCENGGS-CSPEDGSCECAPG 599
CD VTG C C +G RCD C G +G P+C C C C PE GSC G
Sbjct: 827 TVCDQVTGQCPCHGEVSGRRCDR-CLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGG 884
Query: 600 FR-GPLCQRICPPGFYGH-GCAQPCPLCVHSSRP---------CHH----ISGICECLPG 644
F G C+R C G+YG+ QPC C+ P C+ IC CL G
Sbjct: 885 FTTGRNCER-CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQG 943
Query: 645 FSGALCNQVCAGGYFGQDC-----AQLCSCANN------GTCSPIDGSC-QCFPGWIGKD 692
++G C + C+ G++G Q C+C NN +CS + G C +C G +
Sbjct: 944 YTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGAN 1002
Query: 693 CSQACPPGFWGPACFHAC---SCH-NGAS------------CSAEDGACHCTPGWTGLFC 736
C Q C PG +G A C SCH +G S C GAC C P TGL C
Sbjct: 1003 C-QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC 1061
Query: 737 TQRCPAAFFGKDCGRVCQC-------QNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFG 789
RC ++ GR CQ + CD ++G+C C+ G+ G+ C + C +G
Sbjct: 1062 -DRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYG 1119
Query: 790 Y--GCQQLCECMNNST----CDHVTGTCYCSPGFKGIRCDQAA 826
G C+C T CD TG C C G G RCD+ A
Sbjct: 1120 DPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCA 1162
Score = 164 bits (415), Expect = 4e-40
Identities = 141/436 (32%), Positives = 172/436 (39%), Gaps = 91/436 (20%)
Query: 275 CPCHH----GGQCDHVTGQCHCTAGYMGDRCQEECPFGSF--GFQCSQHCDCHNGGQ--- 325
C CH G C + GQC C +G RC + C GS+ G C CH G
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 326 -CSPTTGACECEPGYKGPRCQERLCPEGLHG-PGCTLPCPCDADNTISCHPVTGAC-TCQ 382
C TG C C G RC C G G P C PCPC+ + C P TG+C C
Sbjct: 828 VCDQVTGQCPCHGEVSGRRCDR--CLAGYFGFPSCH-PCPCNRFAEL-CDPETGSCFNCG 883
Query: 383 PGWSGHHCNESCPVGYYGDGCQ----LPCTC-----QNGADCHSITGG-------CTCAP 426
+G +C E C GYYG+ PC C N HS C C
Sbjct: 884 GFTTGRNC-ERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQ 942
Query: 427 GFMGEVCAVSCAAGTYG-PNCSSI----CSCNNG------GTCSPVDGSCT-CKEGWQGL 474
G+ G C C+ G YG P S C+CNN +CS V G C C QG
Sbjct: 943 GYTGTQCG-ECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
+C L C G +G N++C CSC + + CP G G C
Sbjct: 1002 NCQL-CKPGHYGSALNQTCR------------RCSCHASGVSP---MECPPG--GGACL- 1042
Query: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW----GPNCSVSCSCE----NGGS 586
CDPVTG C CL TG+ CD C G W G C SC C+
Sbjct: 1043 ---------CDPVTGACPCLPNVTGLACD-RCADGYWNLVPGRGCQ-SCDCDPRTSQSSH 1091
Query: 587 CSPEDGSCECAPGFRGPLCQRICPPGFYGH--GCAQPCPL-CVHSSRP-CHHISGICECL 642
C G C C G+ G C C +YG G PC + +P C +G+C C
Sbjct: 1092 CDQLTGQCPCKLGYGGKRCSE-CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCR 1150
Query: 643 PGFSGALCNQVCAGGY 658
G SG C++ CA G+
Sbjct: 1151 EGVSGQRCDR-CARGH 1165
Score = 162 bits (409), Expect = 2e-39
Identities = 132/419 (31%), Positives = 166/419 (39%), Gaps = 80/419 (19%)
Query: 215 CEELCPPGSHGAHC-ELRCPCQN----GGTCHHITGECACPPGWTGAVCAQPCPPGTF-- 267
CE L S H + C C G +C + G+C C P G C + C G++
Sbjct: 751 CERLIISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDL 809
Query: 268 GQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNG 323
G + C CH G CD VTGQC C G RC + C G FGF C C+
Sbjct: 810 GHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRC-DRCLAGYFGFPSCHPCPCNRF 868
Query: 324 GQ-CSPTTGAC-ECEPGYKGPRCQERLCPEGLHG-PGCTLPC-PC-----DADNTISCHP 374
+ C P TG+C C G C+ C +G +G P PC PC + N H
Sbjct: 869 AELCDPETGSCFNCGGFTTGRNCER--CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHS 926
Query: 375 V-------TGACTCQPGWSGHHCNESCPVGYYGD------GCQLPCTCQNGAD------C 415
C C G++G C E C G+YG+ CQ PC C N D C
Sbjct: 927 CYQNLWSSDVICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQ-PCACNNNIDVTDPESC 984
Query: 416 HSITGGC-TCAPGFMGEVCAVSCAAGTYGPNCSSI---CSCNNGGT-------------C 458
+TG C C G C + C G YG + CSC+ G C
Sbjct: 985 SRVTGECLRCLHNTQGANCQL-CKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLC 1043
Query: 459 SPVDGSCTCKEGWQGLDCTLPCPSGTW----GLNCNESCTC----ANGAACSPIDGSCSC 510
PV G+C C GL C C G W G C +SC C + + C + G C C
Sbjct: 1044 DPVTGACPCLPNVTGLACD-RCADGYWNLVPGRGC-QSCDCDPRTSQSSHCDQLTGQCPC 1101
Query: 511 TPGWLGDTCELPCPDGTFGLNCSE--HCDCSHADG----CDPVTGHCCCLAGWTGIRCD 563
G+ G C C + +G CDC+ A CDP TG C C G +G RCD
Sbjct: 1102 KLGYGGKRCS-ECQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD 1159
Score = 136 bits (343), Expect = 9e-32
Identities = 117/376 (31%), Positives = 149/376 (39%), Gaps = 75/376 (19%)
Query: 87 QCCPGYYESGDF------CIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGP 140
+C G Y+ G C P +++ V + CH E G C C + ++G
Sbjct: 801 RCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVS--GRRCDR-CLAGYFGF 857
Query: 141 HCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPG-----THGKGCQLPCQCRHG 194
+ C C A LC+P TG+C GF R E C G + G+ C+ PC C
Sbjct: 858 PSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCERCIDGYYGNPSSGQPCR-PCLCPDD 916
Query: 195 ASCDPRAGE------------CLCAPGYTGVYCEELCPPGSH------GAHCELRCPCQN 236
S + C C GYTG C E C G + GA C+ C C N
Sbjct: 917 PSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-CSTGFYGNPRISGAPCQ-PCACNN 974
Query: 237 G------GTCHHITGEC-ACPPGWTGAVCAQPCPPGTFGQNCSQD---CPCHHGG----- 281
+C +TGEC C GA C Q C PG +G +Q C CH G
Sbjct: 975 NIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGHYGSALNQTCRRCSCHASGVSPME 1033
Query: 282 --------QCDHVTGQCHCTAGYMGDRCQEECPFGSFGF---QCSQHCDC----HNGGQC 326
CD VTG C C G C + C G + + Q CDC C
Sbjct: 1034 CPPGGGACLCDPVTGACPCLPNVTGLAC-DRCADGYWNLVPGRGCQSCDCDPRTSQSSHC 1092
Query: 327 SPTTGACECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDADNTIS--CHPVTGACTCQ 382
TG C C+ GY G RC E C E +G PG +PC C+ T C P TG C C+
Sbjct: 1093 DQLTGQCPCKLGYGGKRCSE--CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCR 1150
Query: 383 PGWSGHHCNESCPVGY 398
G SG C + C G+
Sbjct: 1151 EGVSGQRC-DRCARGH 1165
Score = 132 bits (331), Expect = 2e-30
Identities = 118/404 (29%), Positives = 152/404 (37%), Gaps = 85/404 (21%)
Query: 189 CQCRH----GASCDPRAGECLCAPGYTGVYCEELCPPGS-----HGAHCELRCPCQNGGT 239
C+C G+SC G+C C P G C+ C GS HG H C C G+
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCH---PCHCHPQGS 824
Query: 240 ----CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ-CDHVTGQCHCTA 294
C +TG+C C +G C + C G FG CPC+ + CD TG C
Sbjct: 825 KDTVCDQVTGQCPCHGEVSGRRCDR-CLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCG 883
Query: 295 GYMGDRCQEECPFGSFGFQCS----QHCDCHNGGQCS------------PTTGACECEPG 338
G+ R E C G +G S + C C + + + C C G
Sbjct: 884 GFTTGRNCERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQG 943
Query: 339 YKGPRCQERLCPEGLHG-PGCT-LPC-PCDADNTI------SCHPVTGAC-TCQPGWSGH 388
Y G +C E C G +G P + PC PC +N I SC VTG C C G
Sbjct: 944 YTGTQCGE--CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGA 1001
Query: 389 HCNESCPVGYYGDGCQLPC-------------TCQNGAD---CHSITGGCTCAPGFMGEV 432
+C + C G+YG C C G C +TG C C P G
Sbjct: 1002 NC-QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLA 1060
Query: 433 CAVSCAAGTY----GPNCSSICSC----NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGT 484
C CA G + G C S C C + C + G C CK G+ G C+ C
Sbjct: 1061 CD-RCADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENY 1117
Query: 485 WG--------LNCNESCTCANGAACSPIDGSCSCTPGWLGDTCE 520
+G +CN + T C P G C C G G C+
Sbjct: 1118 YGDPPGRCIPCDCNRAGT--QKPICDPDTGMCRCREGVSGQRCD 1159
Score = 115 bits (289), Expect = 2e-25
Identities = 94/306 (30%), Positives = 121/306 (39%), Gaps = 61/306 (19%)
Query: 576 SVSCSCEN----GGSCSPEDGSCECAPGFRGPLCQRICPPGFYG---HGCAQPCPLCVHS 628
+V+C C G SCS G C+C P G C R C G Y HGC PC
Sbjct: 766 AVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGC-HPCHCHPQG 823
Query: 629 SRP--CHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGT-CSPIDGSC-QC 684
S+ C ++G C C SG C++ C GYFG C C C P GSC C
Sbjct: 824 SKDTVCDQVTGQCPCHGEVSGRRCDR-CLAGYFGFPSCHPCPCNRFAELCDPETGSCFNC 882
Query: 685 FPGWIGKDCSQACPPGFWGPACF----HACSCHNGASCS------------AEDGACHCT 728
G++C + C G++G C C + S + + D C+C
Sbjct: 883 GGFTTGRNCER-CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCL 941
Query: 729 PGWTGLFCTQRCPAAFFGKD--CGRVCQ---CQNGA------SCDHISGKCT-CRTGFTG 776
G+TG C + C F+G G CQ C N SC ++G+C C G
Sbjct: 942 QGYTGTQCGE-CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQG 1000
Query: 777 QHCEQRCAPGTFGYGCQQLC-------------ECMNNS---TCDHVTGTCYCSPGFKGI 820
+C Q C PG +G Q C EC CD VTG C C P G+
Sbjct: 1001 ANC-QLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGL 1059
Query: 821 RCDQAA 826
CD+ A
Sbjct: 1060 ACDRCA 1065
Score = 86.3 bits (212), Expect = 1e-16
Identities = 76/270 (28%), Positives = 97/270 (35%), Gaps = 43/270 (15%)
Query: 157 ITGACVCAAGFRGWRCEELC----------APGTHGKGCQLPCQCR-HGASCDPRAGECL 205
+ G CVC G CE A C+ C C H + C L
Sbjct: 291 VHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACR-SCSCNSHSSRCHFDMTTYL 349
Query: 206 CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPG 265
+ G +G CE+ C + G HC+ P I+ AC P + P G
Sbjct: 350 ASGGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP-------CECDPDG 401
Query: 266 TFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS-----QHCDC 320
T C H V GQC C G +C ++C +G + Q CDC
Sbjct: 402 TISGGI---CVSHSDPALGSVAGQCLCKENVEGAKC-DQCKPNHYGLSATDPLGCQPCDC 457
Query: 321 HNGGQ-----CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL----PCPCDADNTIS 371
+ G C TG C C G C+E C G G G L PC CD S
Sbjct: 458 NPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE--CTVGYWGLGNHLHGCSPCDCDIGGAYS 515
Query: 372 --CHPVTGACTCQPGWSGHHCNESCPVGYY 399
C P G C C+P +G C+E P GY+
Sbjct: 516 NVCSPKNGQCECRPHVTGRSCSEPAP-GYF 544
Score = 81.3 bits (199), Expect = 4e-15
Identities = 85/305 (27%), Positives = 114/305 (37%), Gaps = 49/305 (16%)
Query: 436 SCAAGTYGPNCSSICSCNNGGTCSP---VDGSCTCKEGWQGLDCTLPC----------PS 482
SC + C + G SP V G C C+ G +C C P+
Sbjct: 264 SCFCNGHASECRPMQKMR-GDVFSPPGMVHGQCVCQHNTDGPNCER-CKDFFQDAPWRPA 321
Query: 483 GTWGLNCNESCTCANGAACSPIDGSCSCTPGWL-GDTCELPCPDGTFGLNCSEHCDCSHA 541
N SC+C + ++ D + G L G CE C T G +C +
Sbjct: 322 ADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCE-DCQHNTEGQHCDRCRPLFYR 380
Query: 542 DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGFR 601
D ++ C+ CD P G VS S GS + G C C
Sbjct: 381 DPLKTISDPYACIP----CECD---PDGTISGGICVSHSDPALGSVA---GQCLCKENVE 430
Query: 602 GPLCQRICPPGFYGH------GCAQPCPLCVHSSRP---CHHISGICECLPGFSGALCNQ 652
G C + C P YG GC QPC S P C +G C CL +GA C +
Sbjct: 431 GAKCDQ-CKPNHYGLSATDPLGC-QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE 488
Query: 653 VCAGGYFG-----QDCAQLCSC----ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWG 703
C GY+G C+ C C A + CSP +G C+C P G+ CS+ P F+
Sbjct: 489 -CTVGYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFA 546
Query: 704 PACFH 708
P F+
Sbjct: 547 PLNFY 551
Score = 81.3 bits (199), Expect = 4e-15
Identities = 78/293 (26%), Positives = 96/293 (32%), Gaps = 91/293 (31%)
Query: 375 VTGACTCQPGWSGHHCNESC----------PVGYYGDGCQLPCTCQNGAD-CHSITGGCT 423
V G C CQ G +C E C P D C+C + + CH
Sbjct: 291 VHGQCVCQHNTDGPNC-ERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
Query: 424 CAPGFMGEVCAVSCAAGTYGPNCSSI--------------------CSCNNGGTCS---- 459
+ G G VC C T G +C C C+ GT S
Sbjct: 350 ASGGLSGGVCE-DCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGIC 408
Query: 460 ---------PVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSC 510
V G C CKE +G C C +GL+ + C C C
Sbjct: 409 VSHSDPALGSVAGQCLCKENVEGAKCD-QCKPNHYGLSATDPLGCQ----------PCDC 457
Query: 511 TPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGR 570
P LG L CD TG C CL+ TG C+ C G
Sbjct: 458 NP--LGSLPFLT---------------------CDVDTGQCLCLSYVTGAHCEE-CTVGY 493
Query: 571 WG-----PNCSVSCSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFY 614
WG CS C C+ GG+ CSP++G CEC P G C P F+
Sbjct: 494 WGLGNHLHGCS-PCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
Score = 75.9 bits (185), Expect = 2e-13
Identities = 73/298 (24%), Positives = 99/298 (33%), Gaps = 44/298 (14%)
Query: 176 CAPGTHGKGCQLPCQCRHGASCDPRA---GECLCAPGYTGVYCEELC---------PPGS 223
C H C+ P Q G P G+C+C G CE P
Sbjct: 265 CFCNGHASECR-PMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAAD 323
Query: 224 HGAHCELRCPCQNGGT-CHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ 282
+ C C + + CH G +G VC + C T GQ+C + P +
Sbjct: 324 LQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVC-EDCQHNTEGQHCDRCRPLFYRDP 382
Query: 283 CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGP 342
++ C C G C H+ G C C+ +G
Sbjct: 383 LKTISDPYACIP----------CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGA 432
Query: 343 RCQERLCPEGLHGPGCTLPC---PCDADNT-----ISCHPVTGACTCQPGWSGHHCNESC 394
+C + C +G T P PCD + ++C TG C C +G HC E C
Sbjct: 433 KCDQ--CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-C 489
Query: 395 PVGYYGDGCQL----PCTCQNGAD----CHSITGGCTCAPGFMGEVCAVSCAAGTYGP 444
VGY+G G L PC C G C G C C P G C+ + P
Sbjct: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFFAP 547
Score = 74.7 bits (182), Expect = 4e-13
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 22/150 (14%)
Query: 133 CDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGK------GCQ 186
C+ D G C + + G C+C G +C++ C P +G GCQ
Sbjct: 395 CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQ 453
Query: 187 LPCQCRHGAS-----CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELR----CPCQNG 237
PC C S CD G+CLC TG +CEE C G G L C C G
Sbjct: 454 -PCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIG 511
Query: 238 G----TCHHITGECACPPGWTGAVCAQPCP 263
G C G+C C P TG C++P P
Sbjct: 512 GAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
Score = 73.9 bits (180), Expect = 7e-13
Identities = 81/285 (28%), Positives = 97/285 (34%), Gaps = 79/285 (27%)
Query: 536 CDCS-HADGCDP--------------VTGHCCCLAGWTGI---RCDSTCPPGRWGP---- 573
C C+ HA C P V G C C G RC W P
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Query: 574 --NCSVSCSCENGGSCSPED------------GSCE-CAPGFRGPLCQRICPPGFYG--- 615
N SCSC + S D G CE C G C R C P FY
Sbjct: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDR-CRPLFYRDPL 383
Query: 616 ------HGCAQPCP----------LCV-HSSRPCHHISGICECLPGFSGALCNQVCAGGY 658
+ C PC +CV HS ++G C C GA C+Q C +
Sbjct: 384 KTISDPYACI-PCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNH 441
Query: 659 FGQDCA-----QLCSCANNG-----TCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC-F 707
+G Q C C G TC G C C G C + C G+WG
Sbjct: 442 YGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHL 500
Query: 708 HACS---CHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFF 745
H CS C G + CS ++G C C P TG C++ P FF
Sbjct: 501 HGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
Score = 67.0 bits (162), Expect = 9e-11
Identities = 68/263 (25%), Positives = 87/263 (33%), Gaps = 43/263 (16%)
Query: 592 GSCECAPGFRGPLCQRIC---------PPGFYGHGCAQPCPLCVHSSRPCHHISGICECL 642
G C C GP C+R P + C HSSR CH
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSR-CHFDMTTYLAS 351
Query: 643 PGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFW 702
G SG +C C GQ C + I C P C C P
Sbjct: 352 GGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP------CE--CDPD-- 400
Query: 703 GPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCG-----RVCQCQN 757
G C H+ + + G C C G C Q C +G + C C
Sbjct: 401 GTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQPCDCNP 459
Query: 758 GAS-----CDHISGKCTCRTGFTGQHCEQRCAPGTFG-----YGCQQLCEC----MNNST 803
S CD +G+C C + TG HCE+ C G +G +GC C+C ++
Sbjct: 460 LGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSP-CDCDIGGAYSNV 517
Query: 804 CDHVTGTCYCSPGFKGIRCDQAA 826
C G C C P G C + A
Sbjct: 518 CSPKNGQCECRPHVTGRSCSEPA 540
Score = 50.8 bits (120), Expect = 7e-06
Identities = 46/205 (22%), Positives = 67/205 (32%), Gaps = 59/205 (28%)
Query: 678 IDGSCQCFPGWIGKDCSQACPPGF----WGPACFHACSCHNGASCSAEDGACH------- 726
+ G C C G +C + C F W PA + SC++ CH
Sbjct: 291 VHGQCVCQHNTDGPNCER-CKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYL 349
Query: 727 ------------CTPGWTGLFCTQRCPAAFF---------------------GKDCGRVC 753
C G C RC F+ G G +C
Sbjct: 350 ASGGLSGGVCEDCQHNTEGQHC-DRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGIC 408
Query: 754 QCQNGASCDHISGKCTCRTGFTGQHCEQRCAPGTFGY------GCQQLCEC-----MNNS 802
+ + ++G+C C+ G C+Q C P +G GCQ C+C +
Sbjct: 409 VSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGCQP-CDCNPLGSLPFL 466
Query: 803 TCDHVTGTCYCSPGFKGIRCDQAAL 827
TCD TG C C G C++ +
Sbjct: 467 TCDVDTGQCLCLSYVTGAHCEECTV 491
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 164 bits (416), Expect = 3e-40
Identities = 125/337 (37%), Positives = 155/337 (45%), Gaps = 76/337 (22%)
Query: 551 CCCLAGWTGIRCDSTCPPG------RWGPNCS-VSCSCENGGSCSPEDGSCECAPGFRGP 603
C C G+TG C+S C PG + GP S V C+C G+C P G C C+ GP
Sbjct: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 604 LCQRICPPGFYGHGCA------QPCPLCVHSSRPCHHI----SGIC-ECLPGFSGALCNQ 652
C+R C PGFYG+ A QPCP S+ C I +C C PG G C +
Sbjct: 732 SCER-CLPGFYGNPFAGQADDCQPCPCPGQSA--CTTIPESREVVCTHCPPGQRGRRC-E 787
Query: 653 VCAGGYFG---------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDCSQA 696
VC G+FG Q C Q C C+ N G C P+ G C +C G C +
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQ-CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EH 845
Query: 697 CPPGFWGPA--------CFHACSCHNGAS------CSAEDGACHCTPGWTGLFCTQRCPA 742
C GF+G A C CSCH S C G C C P T C+ RC
Sbjct: 846 CQEGFYGSALAPRPADKCM-PCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS-RCYP 903
Query: 743 AFF----GKDCGRVCQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---G 791
FF G+ C R C+C S C +G+CTCR G TGQ C+ RC G FG+ G
Sbjct: 904 GFFDLQPGRGC-RSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACD-RCQLGFFGFSIKG 961
Query: 792 CQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
C + C C ++ C H GTC C PGF+G +CD+
Sbjct: 962 C-RACRCSPLGAASAQC-HENGTCVCRPGFEGYKCDR 996
Score = 152 bits (383), Expect = 2e-36
Identities = 128/394 (32%), Positives = 151/394 (38%), Gaps = 86/394 (21%)
Query: 161 CVCAAGFRGWRCEELCAPGTHGKGCQ-------LPCQCRHGASCDPRAGECLCAPGYTGV 213
C C G+ G CE CAPG + Q +PC C +CDP G C+C+ G
Sbjct: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 214 YCEELCPPGSHG-------AHCELRCPCQNGGTCHHITGE----CA-CPPGWTGAVCAQP 261
CE C PG +G C+ CPC C I C CPPG G C +
Sbjct: 732 SCER-CLPGFYGNPFAGQADDCQ-PCPCPGQSACTTIPESREVVCTHCPPGQRGRRC-EV 788
Query: 262 CPPGTFG---------QNCSQDCPCHHG------GQCDHVTGQC-HCTAGYMGDRCQEEC 305
C G FG Q C Q C C G CD ++G C C GD C E C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQ-CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EHC 846
Query: 306 PFGSFGFQCSQH-------CDCHNGGQ------CSPTTGACECEPGYKGPRCQERLCPEG 352
G +G + C CH G C P TG C C P C C G
Sbjct: 847 QEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR--CYPG 904
Query: 353 LH----GPGCTLPCPCD--ADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYG---DGC 403
G GC C C CHP TG CTC+PG +G C + C +G++G GC
Sbjct: 905 FFDLQPGRGCR-SCKCHPLGSQEDQCHPKTGQCTCRPGVTGQAC-DRCQLGFFGFSIKGC 962
Query: 404 QLPCTCQ----NGADCHSITGGCTCAPGFMGEVC------AVSCAAGTYGPNCSSICSCN 453
+ C C A CH G C C PGF G C A GT+ C S C
Sbjct: 963 R-ACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQCPS-CYAL 1019
Query: 454 NGGTCSPVDGSCTCKEGW-QGLDCTLPCPSGTWG 486
+ + T EGW QG DC P WG
Sbjct: 1020 VKEEAAKLKARLTLTEGWLQGSDCGSP-----WG 1048
Score = 145 bits (367), Expect = 1e-34
Identities = 114/353 (32%), Positives = 149/353 (42%), Gaps = 69/353 (19%)
Query: 422 CTCAPGFMGEVCAVSCAAGTY------GPNCSSI-CSCNNGGTCSPVDGSCTCKEGWQGL 474
C+C G+ G+ C SCA G GP S + C+CN GTC P G C C +G
Sbjct: 673 CSCPTGYTGQFCE-SCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 475 DCTLPCPSGTWGL-------NCNESCTCANGAACSPIDGS----CS-CTPGWLGDTCELP 522
C C G +G +C + C C +AC+ I S C+ C PG G CE+
Sbjct: 732 SCER-CLPGFYGNPFAGQADDC-QPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV- 788
Query: 523 CPDGTFG--------------LNCSEHCDCSHADGCDPVTGHCC-CLAGWTGIRCDSTCP 567
C DG FG CS + D + CDP++GHC CL TG C+ C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-CQ 847
Query: 568 PGRWGPNCS-------VSCSCENGGS------CSPEDGSCECAPGFRGPLCQRICPPGFY 614
G +G + + CSC GS C P G C C P C R C PGF+
Sbjct: 848 EGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR-CYPGFF 906
Query: 615 ----GHGCAQ-PCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC--AQLC 667
G GC C CH +G C C PG +G C++ C G+FG + C
Sbjct: 907 DLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR-CQLGFFGFSIKGCRAC 965
Query: 668 SCANNGTCSPI---DGSCQCFPGWIGKDCSQACPPGFW----GPACFHACSCH 713
C+ G S +G+C C PG+ G C + C F+ G C SC+
Sbjct: 966 RCSPLGAASAQCHENGTCVCRPGFEGYKCDR-CHDNFFLTADGTHCQQCPSCY 1017
Score = 139 bits (350), Expect = 1e-32
Identities = 125/394 (31%), Positives = 155/394 (39%), Gaps = 85/394 (21%)
Query: 379 CTCQPGWSGHHCNESCPVGYYGDGCQ-------LPCTCQNGADCHSITGGCTCAPGFMGE 431
C+C G++G C ESC GY + Q +PCTC C TG C C+ G
Sbjct: 673 CSCPTGYTGQFC-ESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 432 VCAVSCAAGTYG-------PNCSSICSCNNGGTCSPVDGS----CT-CKEGWQGLDCTLP 479
C C G YG +C C C C+ + S CT C G +G C +
Sbjct: 732 SCE-RCLPGFYGNPFAGQADDCQP-CPCPGQSACTTIPESREVVCTHCPPGQRGRRCEV- 788
Query: 480 CPSGTWG---------LNCNESCTCANGAA------CSPIDGSC-SCTPGWLGDTCELPC 523
C G +G C++ C C+ C P+ G C C GD CE C
Sbjct: 789 CDDGFFGDPLGLFGHPQPCHQ-CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCE-HC 846
Query: 524 PDGTFGLNCSEH-------CDCSHADG-------CDPVTGHCCCLAGWTGIRCDSTCPPG 569
+G +G + C C H G CDPVTG C CL T C S C PG
Sbjct: 847 QEGFYGSALAPRPADKCMPCSC-HPQGSVSEQMPCDPVTGQCSCLPHVTARDC-SRCYPG 904
Query: 570 RW----GPNCSVSCSCENGGS----CSPEDGSCECAPGFRGPLCQRICPPGFYG---HGC 618
+ G C SC C GS C P+ G C C PG G C R C GF+G GC
Sbjct: 905 FFDLQPGRGCR-SCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDR-CQLGFFGFSIKGC 962
Query: 619 -AQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYF----GQDCAQLCSC--AN 671
A C +S CH +G C C PGF G C++ C +F G C Q SC
Sbjct: 963 RACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDR-CHDNFFLTADGTHCQQCPSCYALV 1020
Query: 672 NGTCSPIDGSCQCFPGWI-GKDCSQACPPGFWGP 704
+ + GW+ G DC WGP
Sbjct: 1021 KEEAAKLKARLTLTEGWLQGSDCGSP-----WGP 1049
Score = 119 bits (298), Expect = 1e-26
Identities = 114/388 (29%), Positives = 146/388 (37%), Gaps = 71/388 (18%)
Query: 420 GGCTCAPGFMGEVCAVSCAAGTYGP-NCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTL 478
G P F+ EV S G P + ICSC G T + +C G++
Sbjct: 642 GPSPAGPVFLTEVRLTSARPGLSPPASWVEICSCPTGYTGQFCE---SCAPGYKR----- 693
Query: 479 PCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC 538
P G +C CTC C P G C C+ G +CE C G +G + D
Sbjct: 694 EMPQGGPYASC-VPCTCNQHGTCDPNTGICVCSHHTEGPSCER-CLPGFYGNPFAGQADD 751
Query: 539 SHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSV--------------------S 578
C P C + + C + CPPG+ G C V
Sbjct: 752 CQPCPC-PGQSACTTIPESREVVC-THCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQ 809
Query: 579 CSCENG------GSCSPEDGSC-ECAPGFRGPLCQRICPPGFYGHGCA-QPCPLC----- 625
C C G+C P G C C G C+ C GFYG A +P C
Sbjct: 810 CQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-CQEGFYGSALAPRPADKCMPCSC 868
Query: 626 -----VHSSRPCHHISGICECLPGFSGALCNQVCAGGYF----GQDCAQLCSCANNGT-- 674
V PC ++G C CLP + C++ C G+F G+ C C C G+
Sbjct: 869 HPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR-CYPGFFDLQPGRGCRS-CKCHPLGSQE 926
Query: 675 --CSPIDGSCQCFPGWIGKDCSQACPPGFWG---PACFHACSCHNGASCSA---EDGACH 726
C P G C C PG G+ C + C GF+G C AC C + SA E+G C
Sbjct: 927 DQCHPKTGQCTCRPGVTGQACDR-CQLGFFGFSIKGC-RACRCSPLGAASAQCHENGTCV 984
Query: 727 CTPGWTGLFCTQRCPAAFFGKDCGRVCQ 754
C PG+ G C RC FF G CQ
Sbjct: 985 CRPGFEGYKC-DRCHDNFFLTADGTHCQ 1011
Score = 103 bits (258), Expect = 6e-22
Identities = 83/286 (29%), Positives = 107/286 (37%), Gaps = 58/286 (20%)
Query: 594 CECAPGFRGPLCQRICPPGF-----YGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGA 648
C C G+ G C+ C PG+ G A P + C +GIC C G
Sbjct: 673 CSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHTEGP 731
Query: 649 LCNQVCAGGYFGQ------DCAQLCSCANNGTCSPIDGSCQ-----CFPGWIGKDCSQAC 697
C + C G++G D Q C C C+ I S + C PG G+ C + C
Sbjct: 732 SCER-CLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC-EVC 789
Query: 698 PPGFWG--------PACFHACSCHNGA------SCSAEDGAC-HCTPGWTGLFCTQRCPA 742
GF+G P H C C +C G C C TG C + C
Sbjct: 790 DDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHC-EHCQE 848
Query: 743 AFFGK-------DCGRVCQCQNGAS------CDHISGKCTCRTGFTGQHCEQRCAPGTF- 788
F+G D C C S CD ++G+C+C T + C RC PG F
Sbjct: 849 GFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCS-RCYPGFFD 907
Query: 789 ---GYGCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQAAL 827
G GC+ C+C C TG C C PG G CD+ L
Sbjct: 908 LQPGRGCRS-CKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQL 952
Score = 91.3 bits (225), Expect = 4e-18
Identities = 75/244 (30%), Positives = 91/244 (37%), Gaps = 52/244 (21%)
Query: 638 ICECLPGFSGALCNQVCAGGYFGQ--------DCAQLCSCANNGTCSPIDGSCQCFPGWI 689
IC C G++G C CA GY + C C+C +GTC P G C C
Sbjct: 672 ICSCPTGYTGQFCES-CAPGYKREMPQGGPYASCVP-CTCNQHGTCDPNTGICVCSHHTE 729
Query: 690 GKDCSQACPPGFWG-PACFHA-----CSCHNGASC-----SAEDGACHCTPGWTGLFCTQ 738
G C + C PGF+G P A C C ++C S E HC PG G C +
Sbjct: 730 GPSCER-CLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC-E 787
Query: 739 RCPAAFFGKDCG--------RVCQCQNGA------SCDHISGKCT-CRTGFTGQHCEQRC 783
C FFG G CQC +CD +SG C C TG HCE C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCEH-C 846
Query: 784 APGTFGYGCQQL-------CECMNNST------CDHVTGTCYCSPGFKGIRCDQAALMME 830
G +G C C + CD VTG C C P C +
Sbjct: 847 QEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFF 906
Query: 831 ELNP 834
+L P
Sbjct: 907 DLQP 910
Score = 72.0 bits (175), Expect = 3e-12
Identities = 67/238 (28%), Positives = 89/238 (37%), Gaps = 45/238 (18%)
Query: 237 GGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCS------QDCPCHHG-GQCDHVTGQ 289
GG C C P G + + C T G +C QD P G + H
Sbjct: 268 GGRCKCNGHASECGPDVAGQLACR-CQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
Query: 290 CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLC 349
C+C+ EEC F F+ + H GG+C C GP C+ C
Sbjct: 327 CNCSGR------SEECTFDRELFRSTGH-----GGRCH------HCRDHTAGPHCER--C 367
Query: 350 PEGLHGPGCTLPC-PCDADNTISCH---PVTGACTCQPGWSGHHCNESCPVGYYG---DG 402
E + +PC PCD + S H TG C C+P +G C+ P G++ G
Sbjct: 368 QENFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLP-GFHSLSEGG 426
Query: 403 CQLPCTCQNGAD---CHSITGGCTCAPGFMGEVCAVSCAAGTY-----GPNCSSICSC 452
C+ PCTC C +G C C G +C C GT+ P S C C
Sbjct: 427 CR-PCTCNPAGSLDTCDPRSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGCSSCFC 482
Score = 71.2 bits (173), Expect = 5e-12
Identities = 55/156 (35%), Positives = 70/156 (44%), Gaps = 28/156 (17%)
Query: 91 GYYESGDFCIPL-CT---EECVHGRCVSPDT-----CH-CEPGWGGPDCSSGCDSD--HW 138
G E+ C+P C+ EEC R + T CH C GP C C + HW
Sbjct: 316 GTAEAAHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCER-CQENFYHW 374
Query: 139 GPHCSNR-CQCQN-GAL---CNPITGACVCAAGFRGWRCEELCAPGTHGK---GCQLPCQ 190
P + C CQ+ G+L C+ TG C C GW+C+ C PG H GC+ PC
Sbjct: 375 DPRMPCQPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDR-CLPGFHSLSEGGCR-PCT 431
Query: 191 CRHGAS---CDPRAGECLCAPGYTGVYCEELCPPGS 223
C S CDPR+G C C G C+ C PG+
Sbjct: 432 CNPAGSLDTCDPRSGRCPCKENVEGNLCDR-CRPGT 466
Score = 64.3 bits (155), Expect = 6e-10
Identities = 69/240 (28%), Positives = 82/240 (34%), Gaps = 42/240 (17%)
Query: 584 GGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLP 643
GG C + EC P G L R C G C + P ECLP
Sbjct: 268 GGRCKCNGHASECGPDVAGQLACR-CQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLP 326
Query: 644 GFSGALCNQVCAGGYFGQDCA----QLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPP 699
CN C+G ++C S + G C C G C + C
Sbjct: 327 ------CN--CSGR--SEECTFDRELFRSTGHGGRCH------HCRDHTAGPHC-ERCQE 369
Query: 700 GF--WGPAC-FHACSCHNGASCSA---EDGACHCTPGWTGLFCTQRCPAAFFGKDCG--R 751
F W P C C + S + G C C P TG C RC F G R
Sbjct: 370 NFYHWDPRMPCQPCDCQSAGSLHLQCDDTGTCACKPTVTGWKC-DRCLPGFHSLSEGGCR 428
Query: 752 VCQCQNGAS---CDHISGKCTCRTGFTGQHCEQRCAPGTFGY------GCQQLCECMNNS 802
C C S CD SG+C C+ G C+ RC PGTF GC C C +S
Sbjct: 429 PCTCNPAGSLDTCDPRSGRCPCKENVEGNLCD-RCRPGTFNLQPHNPAGCSS-CFCYGHS 486
Score = 61.2 bits (147), Expect = 5e-09
Identities = 66/227 (29%), Positives = 80/227 (35%), Gaps = 45/227 (19%)
Query: 450 CSCN-NGGTCSP-VDG--SCTCKEGWQGLDCTLPCP---SGTWGLNCNES------CTCA 496
C CN + C P V G +C C+ G DC P W E+ C C+
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 497 NGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS---------------EHCDCSHA 541
+ D + G G C C D T G +C + CDC A
Sbjct: 331 GRSEECTFDRELFRSTGH-GGRCH-HCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSA 388
Query: 542 DG----CDPVTGHCCCLAGWTGIRCDSTCPPG--RWGPNCSVSCSCENGGS---CSPEDG 592
CD TG C C TG +CD C PG C+C GS C P G
Sbjct: 389 GSLHLQCDD-TGTCACKPTVTGWKCDR-CLPGFHSLSEGGCRPCTCNPAGSLDTCDPRSG 446
Query: 593 SCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGIC 639
C C G LC R C PG + QP SS C+ S +C
Sbjct: 447 RCPCKENVEGNLCDR-CRPGTFN---LQPHNPAGCSSCFCYGHSKVC 489
Score = 59.3 bits (142), Expect = 2e-08
Identities = 64/245 (26%), Positives = 81/245 (33%), Gaps = 60/245 (24%)
Query: 189 CQCR-HGASCDPR-AGE--CLCAPGYTGVYCEELCP-----PGSHG----AHCELRCPCQ 235
C+C H + C P AG+ C C TG CE P P + G AH L C C
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 236 -----------------NGGTCHHITGECA------CPPGWTGAVCAQPCPPGTFGQNCS 272
+GG CHH A C + PC P
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQP-------- 382
Query: 273 QDCPCHHGG----QCDHVTGQCHCTAGYMGDRCQEECP-FGSFGFQCSQHCDCHNGGQ-- 325
C C G QCD TG C C G +C P F S + C C+ G
Sbjct: 383 --CDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD 439
Query: 326 -CSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPG 384
C P +G C C+ +G C C G P C ++ C+ + C
Sbjct: 440 TCDPRSGRCPCKENVEGNLCDR--CRPGTFNLQPHNPAGC---SSCFCYGHSKVCASTAQ 494
Query: 385 WSGHH 389
+ HH
Sbjct: 495 FQVHH 499
Score = 58.2 bits (139), Expect = 4e-08
Identities = 61/206 (29%), Positives = 80/206 (38%), Gaps = 41/206 (19%)
Query: 667 CSCANNGT-CSP-IDG--SCQCFPGWIGKDCSQACP-----PGFWGPA-CFHACSCHNGA 716
C C + + C P + G +C+C G DC + P P G A H C N +
Sbjct: 271 CKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCS 330
Query: 717 SCSAE-------------DGACH-CTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQNGA 759
S E G CH C G C +RC F+ D CQ CQ+
Sbjct: 331 GRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHC-ERCQENFYHWDPRMPCQPCDCQSAG 389
Query: 760 S----CDHISGKCTCRTGFTGQHCEQRCAPGTFGY---GCQQLCECM---NNSTCDHVTG 809
S CD +G C C+ TG C+ RC PG GC+ C C + TCD +G
Sbjct: 390 SLHLQCDD-TGTCACKPTVTGWKCD-RCLPGFHSLSEGGCRP-CTCNPAGSLDTCDPRSG 446
Query: 810 TCYCSPGFKGIRCDQAALMMEELNPY 835
C C +G CD+ L P+
Sbjct: 447 RCPCKENVEGNLCDRCRPGTFNLQPH 472
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 158 bits (399), Expect = 3e-38
Identities = 154/519 (29%), Positives = 194/519 (37%), Gaps = 102/519 (19%)
Query: 379 CTCQPGWSGHHCNESCPVGYYG-DGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSC 437
C C G++G C ESC GYY DG CQ +CH C + VC ++C
Sbjct: 709 CECPQGYTGTSC-ESCLSGYYRVDGILFGGICQP-CECHGHAAECN-----VHGVC-IAC 760
Query: 438 AAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCAN 497
A T G +C G G C Q C L S + C+ +
Sbjct: 761 AHNTTGVHCEQCLPGFYGEPSRGTPGDC------QPCACPLTIASNNFSPTCH--LNDGD 812
Query: 498 GAACSPIDGSCSCTPGWLGDTCELPCPDGTFG-----------LNCSEHCDCSHADGCDP 546
C C PG+ G CE C DG +G +CS + D S A CD
Sbjct: 813 EVVCD------WCAPGYSGAWCER-CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDS 865
Query: 547 VTGHCC-CLAGWTGIRCDSTCPPGRWGP-----NCSVSCSCENGGS----CSPEDGSCEC 596
VTG C CL G C+ C G +G NC +C C GS C E G C+C
Sbjct: 866 VTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNCR-ACECHVKGSHSAVCHLETGLCDC 923
Query: 597 APGFRGPLCQRICPPGFYG----HGCAQPCPLCVHSSRP--CHHISGICECLPGFSGALC 650
P G C + C G+YG HGC +PC V S C G C C+PG +G C
Sbjct: 924 KPNVTGQQCDQ-CLHGYYGLDSGHGC-RPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRC 980
Query: 651 NQVCAGGYFGQD--CAQLCSCANN-GTCSPIDGSCQCFPGWIGKDCSQACPPGFWG---- 703
++ G Y QD C C C + TC P G C C P G C + C G WG
Sbjct: 981 DRCAHGFYAYQDGSCTP-CDCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAE 1038
Query: 704 PACFHACSCHNGAS----CSAEDGACHCTPGWTGLFCTQRCPAAFFGKDC---------- 749
C AC+C S C G C C + G C Q DC
Sbjct: 1039 VGC-QACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDFPDCVPCDCDLRGT 1097
Query: 750 -GRVCQCQNG-ASCDHISGKCTCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHV 807
G C + G C +G C C+ G C + C GTF D+
Sbjct: 1098 SGDACNLEQGLCGCVEETGACPCKENVFGPQCNE-CREGTFAL------------RADNP 1144
Query: 808 TGTCYCSPGFKGIRCDQAALMMEELNPYTKISPALGAER 846
G CSP F C + + EL Y + LG+++
Sbjct: 1145 LG---CSPCF----CSGLSHLCSELEDYVRTPVTLGSDQ 1176
Score = 156 bits (395), Expect = 8e-38
Identities = 137/468 (29%), Positives = 175/468 (37%), Gaps = 96/468 (20%)
Query: 204 CLCAPGYTGVYCEELCPPGSH-------GAHCELRCPCQNGGTCHHITGEC-------AC 249
C C GYTG CE C G + G C+ PC+ CH EC AC
Sbjct: 709 CECPQGYTGTSCES-CLSGYYRVDGILFGGICQ---PCE----CHGHAAECNVHGVCIAC 760
Query: 250 PPGWTGAVCAQPCPPGTFGQ-------NCSQDCPCHHGGQCDHVTGQCH----------- 291
TG C Q C PG +G+ +C Q C C ++ + CH
Sbjct: 761 AHNTTGVHCEQ-CLPGFYGEPSRGTPGDC-QPCACPLTIASNNFSPTCHLNDGDEVVCDW 818
Query: 292 CTAGYMGDRCQEECPFGSFG-----------FQCSQHCDCHNGGQCSPTTGAC-ECEPGY 339
C GY G C E C G +G CS + D G C TG C +C
Sbjct: 819 CAPGYSGAWC-ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNT 877
Query: 340 KGPRCQERLCPEGLHGPGCTL----PCPCDADNTIS--CHPVTGACTCQPGWSGHHCNES 393
G C+ C +G +G T C C + S CH TG C C+P +G C++
Sbjct: 878 DGAHCER--CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ- 934
Query: 394 CPVGYY----GDGCQLPCTCQ---NGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC 446
C GYY G GC+ PC C + +D + G C C PG G+ C CA G Y
Sbjct: 935 CLHGYYGLDSGHGCR-PCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQD 992
Query: 447 SSICSC---NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGA---- 499
S C + TC P G C C QG+ C C G WG + C N +
Sbjct: 993 GSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCE-ECEDGHWGYDAEVGCQACNCSLVGS 1051
Query: 500 ---ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC----SHADGCDPVTGHCC 552
C + G C C + G C+ C G CDC + D C+ G C
Sbjct: 1052 THHRCDVVTGHCQCKSKFGGRACD-QCSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCG 1110
Query: 553 CLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCECAPGF 600
C+ TG C +GP C+ C G D C+P F
Sbjct: 1111 CVEE-TGA---CPCKENVFGPQCN---ECREGTFALRADNPLGCSPCF 1151
Score = 153 bits (386), Expect = 9e-37
Identities = 139/460 (30%), Positives = 177/460 (38%), Gaps = 82/460 (17%)
Query: 333 CECEPGYKGPRCQERLCP----EGLHGPGCTLPCPCDADNTISCHPVTGAC-TCQPGWSG 387
CEC GY G C+ L +G+ G PC C + C+ V G C C +G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHG-HAAECN-VHGVCIACAHNTTG 766
Query: 388 HHCNESCPVGYYGD-------GCQLPCTC-------QNGADCHSITGG---CT-CAPGFM 429
HC E C G+YG+ CQ PC C CH G C CAPG+
Sbjct: 767 VHC-EQCLPGFYGEPSRGTPGDCQ-PCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 430 GEVCAVSCAAGTYGP-----------NCSSICSCNNGGTCSPVDGSCT-CKEGWQGLDCT 477
G C CA G YG +CS + G C V G C C G C
Sbjct: 825 GAWCE-RCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE 883
Query: 478 LPCPSGTWG-----LNCNESCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPDGTF 528
C G +G NC +C C ++ A C G C C P G C+ C G +
Sbjct: 884 R-CADGFYGDAVTAKNCR-ACECHVKGSHSAVCHLETGLCDCKPNVTGQQCD-QCLHGYY 940
Query: 529 GLNCSEHC---DCSHA----DGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG--PNCSVSC 579
GL+ C +CS A DGC G C C+ G G RCD C G + C
Sbjct: 941 GLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDR-CAHGFYAYQDGSCTPC 998
Query: 580 SCENG-GSCSPEDGSCECAPGFRGPLCQRICPPGFYGH----GC-AQPCPLCVHSSRPCH 633
C + +C PE G C C P +G C+ C G +G+ GC A C L + C
Sbjct: 999 DCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCD 1057
Query: 634 HISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGT----CSPIDGSCQCFPGWI 689
++G C+C F G C+Q G DC C C GT C+ G C C +
Sbjct: 1058 VVTGHCQCKSKFGGRACDQCSLGYRDFPDCVP-CDCDLRGTSGDACNLEQGLCGC----V 1112
Query: 690 GKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTP 729
+ + C +GP C C G D C+P
Sbjct: 1113 EETGACPCKENVFGPQC---NECREGTFALRADNPLGCSP 1149
Score = 150 bits (380), Expect = 5e-36
Identities = 140/449 (31%), Positives = 175/449 (38%), Gaps = 93/449 (20%)
Query: 88 CCPGYYES-----GDFCIPL-C---TEEC-VHGRCVS----PDTCHCE---PGWGGPDCS 130
C GYY G C P C EC VHG C++ HCE PG+ G + S
Sbjct: 723 CLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGVHCEQCLPGFYG-EPS 781
Query: 131 SGCDSDHWGPHCSNRCQCQNGALCNPITGACV-----------CAAGFRGWRCEELCAPG 179
G D C C N + C CA G+ G CE CA G
Sbjct: 782 RGTPGD------CQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER-CADG 834
Query: 180 THG------KGCQLPCQCR------HGASCDPRAGECLCAPGYT-GVYCEELCPPGSHG- 225
+G + C +PC C CD GECL G T G +CE C G +G
Sbjct: 835 YYGNPTVPGESC-VPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER-CADGFYGD 892
Query: 226 -------AHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDC-PC 277
CE + CH TG C C P TG C Q C G +G + C PC
Sbjct: 893 AVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPC 951
Query: 278 H---HGGQCDHVT--GQCHCTAGYMGDRCQEECPFGSFGFQ---CSQHCDC-HNGGQCSP 328
+ G D T GQCHC G G RC + C G + +Q C+ CDC H C P
Sbjct: 952 NCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTP-CDCPHTQNTCDP 1009
Query: 329 TTGACECEPGYKGPRCQERLCPEGLHG----PGCTLPCPCDADNTI--SCHPVTGACTCQ 382
TG C C P +G +C+E C +G G GC C C + C VTG C C+
Sbjct: 1010 ETGECVCPPHTQGVKCEE--CEDGHWGYDAEVGCQ-ACNCSLVGSTHHRCDVVTGHCQCK 1066
Query: 383 PGWSGHHCNESCPVGYYGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCA 438
+ G C++ C +GY +PC C +G C+ G C C + E A C
Sbjct: 1067 SKFGGRACDQ-CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGC----VEETGACPCK 1121
Query: 439 AGTYGPNCSSICSCNNGGTCSPVDGSCTC 467
+GP C+ C G D C
Sbjct: 1122 ENVFGPQCN---ECREGTFALRADNPLGC 1147
Score = 149 bits (375), Expect = 2e-35
Identities = 111/328 (33%), Positives = 148/328 (45%), Gaps = 61/328 (18%)
Query: 550 HCCCLAGWTGIRCDSTCPPGRW-------GPNCSVSCSCE-NGGSCSPEDGSCECAPGFR 601
HC C G+TG C+S C G + G C C C + C+ CA
Sbjct: 708 HCECPQGYTGTSCES-CLSGYYRVDGILFGGICQ-PCECHGHAAECNVHGVCIACAHNTT 765
Query: 602 GPLCQRICPPGFYGH------GCAQPC--PLCVHS---SRPCHHISG---ICE-CLPGFS 646
G C++ C PGFYG G QPC PL + S S CH G +C+ C PG+S
Sbjct: 766 GVHCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 647 GALCNQVCAGGYFG------QDCAQLCSCANN------GTCSPIDGSC-QCFPGWIGKDC 693
GA C + CA GY+G + C C C+ N G C + G C +C G C
Sbjct: 825 GAWCER-CADGYYGNPTVPGESCVP-CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
Query: 694 SQACPPGFWGPACF----HACSCH----NGASCSAEDGACHCTPGWTGLFCTQRCPAAFF 745
+ C GF+G A AC CH + A C E G C C P TG C Q C ++
Sbjct: 883 ER-CADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYY 940
Query: 746 GKDCGRVCQCQNGASCDHIS------GKCTCRTGFTGQHCEQRCAPGTFGY--GCQQLCE 797
G D G C+ N + +S G+C C G G+ C+ RCA G + Y G C+
Sbjct: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDGSCTPCD 999
Query: 798 CMNN-STCDHVTGTCYCSPGFKGIRCDQ 824
C + +TCD TG C C P +G++C++
Sbjct: 1000 CPHTQNTCDPETGECVCPPHTQGVKCEE 1027
Score = 77.4 bits (189), Expect = 6e-14
Identities = 63/211 (29%), Positives = 82/211 (38%), Gaps = 56/211 (26%)
Query: 161 CVCAAGFRGWRCEELCAPGTH--------GKGCQ------LPCQCR-HGASCDPRAGECL 205
CVC G G+ C++ CAPG H +G + +PC C H +CDP G+CL
Sbjct: 1362 CVCPPGTVGFSCQD-CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 206 -CAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPP 264
C G +C+ +C G +G C CACP PP
Sbjct: 1421 NCGDNTAGDHCD-VCTSGYYGKVTGSASDC----------ALCACPHS----------PP 1459
Query: 265 GTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS-----QHCD 319
+F C + H +CD C GY G C E C +G + Q CD
Sbjct: 1460 ASFSPTCVLEGD--HDFRCDA------CLLGYEGKHC-ERCSSSYYGNPQTPGGSCQKCD 1510
Query: 320 CHNGGQ----CSPTTGACECEPGYKGPRCQE 346
C+ G C T+G C C G G RC E
Sbjct: 1511 CNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
Score = 72.0 bits (175), Expect = 3e-12
Identities = 77/287 (26%), Positives = 105/287 (36%), Gaps = 54/287 (18%)
Query: 175 LCAPGTHGKGC-------QLPCQCRH---GASCDPRAGECLCAPGYTGVYCEELCPPG-- 222
+C H C +L CQC H G SC+ C PGY ++ PG
Sbjct: 269 MCICYGHASSCPWDETTKKLQCQCEHNTCGESCNR------CCPGYH----QQPWRPGTV 318
Query: 223 SHGAHCELRCPCQNGGT-CHHITGECACPPGWT-------GAVCAQPCPPGTFGQNCSQD 274
S G CE C C N C++ G VC C T G NC
Sbjct: 319 SSGNTCEA-CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCIN-CLQNTMGINCET- 375
Query: 275 CPCHHGGQCDHVTGQCHCTAGYMGDRCQE-EC-PFGSFGFQCSQ---HCDCHNGGQCSPT 329
C + H + Y + C+ C P GS C + H D HNG Q
Sbjct: 376 --------CIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQ---- 423
Query: 330 TGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
G C C+ GY G +C C G + C C+ + S P TG C C+ G
Sbjct: 424 PGQCPCKEGYTGEKCDR--CQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKA 481
Query: 390 CNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVS 436
C + C G+Y + P C C ++ C+ +G+V ++S
Sbjct: 482 C-DRCKPGFYNLKEKNPRGCSE-CFCFGVSDVCSSLSWPVGQVNSMS 526
Score = 71.2 bits (173), Expect = 5e-12
Identities = 65/213 (30%), Positives = 80/213 (37%), Gaps = 60/213 (28%)
Query: 639 CECLPGFSGALCNQVCAGGYF------GQD---------CAQLCSCANNG-TCSPIDGSC 682
C C PG G C Q CA GY G D C CSC N+ TC P G C
Sbjct: 1362 CVCPPGTVGFSC-QDCAPGYHRGKLPAGSDRGPRPLVAPCVP-CSCNNHSDTCDPNTGKC 1419
Query: 683 -QCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCP 741
C G C C G++G A C C C P
Sbjct: 1420 LNCGDNTAGDHCD-VCTSGYYGKVTGSASDC----------ALCACP----------HSP 1458
Query: 742 AAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCA------PGTFGYGCQQL 795
A F C V + + CD C G+ G+HCE RC+ P T G CQ+
Sbjct: 1459 PASFSPTC--VLEGDHDFRCD------ACLLGYEGKHCE-RCSSSYYGNPQTPGGSCQK- 1508
Query: 796 CECMNNST----CDHVTGTCYCSPGFKGIRCDQ 824
C+C + + CD +G C C G G+RCD+
Sbjct: 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
Score = 69.7 bits (169), Expect = 1e-11
Identities = 75/277 (27%), Positives = 97/277 (35%), Gaps = 64/277 (23%)
Query: 379 CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCA 438
C C+ G CN CP GY+ + P T +G C + C C + C +
Sbjct: 290 CQCEHNTCGESCNRCCP-GYHQQPWR-PGTVSSGNTCEA----CNCHN--KAKDCYYDES 341
Query: 439 AGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANG 498
+ ++ GG C + C T G+NC TC +G
Sbjct: 342 VAKQKKSLNTAGQFRGGGVC-------------------INCLQNTMGINCE---TCIDG 379
Query: 499 A----ACSPIDGS----CSCTP-GWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG 549
SP + C+C P G L C + H D + G P G
Sbjct: 380 YYRPHKVSPYEDEPCRPCNCDPVGSLSSVC----------IKDDLHSDLHN--GKQP--G 425
Query: 550 HCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPE--DGSCECAPGFRGPLCQR 607
C C G+TG +CD + P C VSC C GS S E G C C G C R
Sbjct: 426 QCPCKEGYTGEKCDRCQLGYKDYPTC-VSCGCNPVGSASDEPCTGPCVCKENVEGKACDR 484
Query: 608 ICPPGFYGHGCAQP--CPLCVHSSRPCHHISGICECL 642
C PGFY P C C C +S +C L
Sbjct: 485 -CKPGFYNLKEKNPRGCSECF-----CFGVSDVCSSL 515
Score = 63.9 bits (154), Expect = 7e-10
Identities = 64/208 (30%), Positives = 80/208 (38%), Gaps = 47/208 (22%)
Query: 417 SITGGCTCAPGFMGEVCAVSCAAGTY----------GPN-----CSSICSCNN-GGTCSP 460
S+ C C PG +G C CA G + GP C CSCNN TC P
Sbjct: 1357 SLLENCVCPPGTVGFSCQ-DCAPGYHRGKLPAGSDRGPRPLVAPCVP-CSCNNHSDTCDP 1414
Query: 461 VDGSC-TCKEGWQGLDCTLPCPSGTWGLNCNESCTCA-------NGAACSPI-------D 505
G C C + G C + C SG +G + CA A+ SP D
Sbjct: 1415 NTGKCLNCGDNTAGDHCDV-CTSGYYGKVTGSASDCALCACPHSPPASFSPTCVLEGDHD 1473
Query: 506 GSC-SCTPGWLGDTCELPCPDGTFGL-----NCSEHCDCS-----HADGCDPVTGHCCCL 554
C +C G+ G CE C +G + CDC+ H D CD +G C C
Sbjct: 1474 FRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGD-CDRTSGQCVCR 1531
Query: 555 AGWTGIRCDSTCPPGRWGPNCSVSCSCE 582
G +G+RCD P VSC E
Sbjct: 1532 LGASGLRCDECEPRHILMETDCVSCDDE 1559
Score = 63.5 bits (153), Expect = 1e-09
Identities = 60/197 (30%), Positives = 81/197 (41%), Gaps = 43/197 (21%)
Query: 480 CPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCS 539
CP GT G +C + CA G + P L C +PC +C+ +
Sbjct: 1364 CPPGTVGFSCQD---CAPGYHRGKLPAGSDRGPRPLVAPC-VPC-------SCN-----N 1407
Query: 540 HADGCDPVTGHCC-CLAGWTGIRCDSTCPPGRWGP------NCSVSCSCENG--GSCSP- 589
H+D CDP TG C C G CD C G +G +C++ C+C + S SP
Sbjct: 1408 HSDTCDPNTGKCLNCGDNTAGDHCD-VCTSGYYGKVTGSASDCAL-CACPHSPPASFSPT 1465
Query: 590 ------EDGSCE-CAPGFRGPLCQRICPPGFYGH-----GCAQPCPLCVHSS--RPCHHI 635
D C+ C G+ G C+R C +YG+ G Q C H S C
Sbjct: 1466 CVLEGDHDFRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRT 1524
Query: 636 SGICECLPGFSGALCNQ 652
SG C C G SG C++
Sbjct: 1525 SGQCVCRLGASGLRCDE 1541
Score = 62.0 bits (149), Expect = 3e-09
Identities = 61/223 (27%), Positives = 86/223 (38%), Gaps = 69/223 (30%)
Query: 593 SCECAPGFRGPLCQRICPPGFY-----GHGCAQPCPL--------CVHSSRPCHHISGIC 639
+C C PG G CQ C PG++ P PL C + S C +G C
Sbjct: 1361 NCVCPPGTVGFSCQD-CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKC 1419
Query: 640 -ECLPGFSGALCNQVCAGGYFGQ------DCAQLCSCANNGTCSPIDGSCQCFPGWIGKD 692
C +G C+ VC GY+G+ DCA LC+C ++
Sbjct: 1420 LNCGDNTAGDHCD-VCTSGYYGKVTGSASDCA-LCACPHS-------------------- 1457
Query: 693 CSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGK----- 747
PP + P C + C A C G+ G C +RC ++++G
Sbjct: 1458 -----PPASFSPTC--VLEGDHDFRCDA------CLLGYEGKHC-ERCSSSYYGNPQTPG 1503
Query: 748 -DCGRVCQCQNGAS----CDHISGKCTCRTGFTGQHCEQRCAP 785
C + C C S CD SG+C CR G +G C++ C P
Sbjct: 1504 GSCQK-CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
Score = 60.5 bits (145), Expect = 8e-09
Identities = 59/213 (27%), Positives = 71/213 (33%), Gaps = 61/213 (28%)
Query: 247 CACPPGWTGAVCAQPCPPGTFGQNCSQD--------------CPCH-HGGQCDHVTGQC- 290
C CPPG G C Q C PG C C+ H CD TG+C
Sbjct: 1362 CVCPPGTVGFSC-QDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 291 HCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCP 350
+C GD C + C G +G DC C C P
Sbjct: 1421 NCGDNTAGDHC-DVCTSGYYGKVTGSASDC----------ALCACPHS-----------P 1458
Query: 351 EGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGD------GCQ 404
P C L + D+ C C G+ G HC E C YYG+ CQ
Sbjct: 1459 PASFSPTCVL----EGDHDFRCD------ACLLGYEGKHC-ERCSSSYYGNPQTPGGSCQ 1507
Query: 405 LPCTCQ-NGA---DCHSITGGCTCAPGFMGEVC 433
C C +G+ DC +G C C G G C
Sbjct: 1508 -KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRC 1539
Score = 56.6 bits (135), Expect = 1e-07
Identities = 55/233 (23%), Positives = 85/233 (36%), Gaps = 68/233 (29%)
Query: 666 LCSCANNGTCSPIDGS-----CQCFPGWIGKDCSQACPPGF----WGPACF------HAC 710
+C C + + P D + CQC G+ C++ CP G+ W P AC
Sbjct: 269 MCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCP-GYHQQPWRPGTVSSGNTCEAC 327
Query: 711 SCHNGASCSAED-------------------GAC-HCTPGWTGLFCTQRCPAAFF----- 745
+CHN A D G C +C G+ C + C ++
Sbjct: 328 NCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINC-ETCIDGYYRPHKV 386
Query: 746 ----GKDCGRVCQCQNGASCDHIS---------------GKCTCRTGFTGQHCEQRCAPG 786
+ C R C C S + G+C C+ G+TG+ C+ RC G
Sbjct: 387 SPYEDEPC-RPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCD-RCQLG 444
Query: 787 TFGYGCQQLCEC--MNNSTCDHVTGTCYCSPGFKGIRCDQAA---LMMEELNP 834
Y C C + +++ + TG C C +G CD+ ++E NP
Sbjct: 445 YKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNP 497
Score = 51.6 bits (122), Expect = 4e-06
Identities = 76/297 (25%), Positives = 100/297 (33%), Gaps = 72/297 (24%)
Query: 493 CTCANGAACSPIDGS-----CSCTPGWLGDTCELPCPD--------GTFGL-NCSEHCDC 538
C C A+ P D + C C G++C CP GT N E C+C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNC 329
Query: 539 SH-ADGC---DPVT--------------GHCC--CLAGWTGIRCDSTCPPGRWGPNCSVS 578
+ A C + V G C CL GI C+ TC G + P+
Sbjct: 330 HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCE-TCIDGYYRPH---K 385
Query: 579 CSCENGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI 638
S C P C C P G C + +HS G
Sbjct: 386 VSPYEDEPCRP----CNCDP------------VGSLSSVCIKDD---LHSDLHNGKQPGQ 426
Query: 639 CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCS--PIDGSCQCFPGWIGKDCSQA 696
C C G++G C++ C GY C C G+ S P G C C GK C +
Sbjct: 427 CPCKEGYTGEKCDR-CQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACDR- 484
Query: 697 CPPGFW-----GPACFHACSCHN----GASCSAEDGACHCTPGW--TGLFCTQRCPA 742
C PGF+ P C C +S S G + GW T L ++ P+
Sbjct: 485 CKPGFYNLKEKNPRGCSECFCFGVSDVCSSLSWPVGQVNSMSGWLVTDLISPRKIPS 541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/178 (26%), Positives = 67/178 (37%), Gaps = 53/178 (29%)
Query: 88 CCPGYYESGDFCIPLCTEE--------CVHGRCVS-PDTC--------HCEPGWGGPDCS 130
C PGY+ +P ++ CV C + DTC +C G C
Sbjct: 1376 CAPGYHRGK---LPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCD 1432
Query: 131 SGCDSDHWGPHCSNRCQCQNGALCN-------PITGACV-----------CAAGFRGWRC 172
C S ++G + C ALC + CV C G+ G C
Sbjct: 1433 V-CTSGYYGKVTGSASDC---ALCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHC 1488
Query: 173 EELCA-----PGTHGKGCQLPCQCR-HGA---SCDPRAGECLCAPGYTGVYCEELCPP 221
E + P T G CQ C C HG+ CD +G+C+C G +G+ C+E C P
Sbjct: 1489 ERCSSSYYGNPQTPGGSCQ-KCDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
Score = 40.0 bits (92), Expect = 0.011
Identities = 52/225 (23%), Positives = 78/225 (34%), Gaps = 54/225 (24%)
Query: 86 SQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
++CCPGY++ + G S +TC +C + ++ + +
Sbjct: 302 NRCCPGYHQ----------QPWRPGTVSSGNTCE------ACNCHNKAKDCYYDESVAKQ 345
Query: 146 CQCQNGALCNPITGACV-CAAGFRGWRCEELCAPGTHGKGCQLPCQ---CRHGASCDP-- 199
+ N A G C+ C G C E C G + P + CR +CDP
Sbjct: 346 KKSLNTAGQFRGGGVCINCLQNTMGINC-ETCIDGYYRPHKVSPYEDEPCR-PCNCDPVG 403
Query: 200 -------------------RAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTC 240
+ G+C C GYTG C+ C G + C C G+
Sbjct: 404 SLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDR-CQLGYKDYPTCVSCGCNPVGSA 462
Query: 241 --HHITGECACPPGWTGAVCAQPCPPGTFG------QNCSQDCPC 277
TG C C G C + C PG + + CS +C C
Sbjct: 463 SDEPCTGPCVCKENVEGKACDR-CKPGFYNLKEKNPRGCS-ECFC 505
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 152 bits (385), Expect = 1e-36
Identities = 242/891 (27%), Positives = 306/891 (34%), Gaps = 211/891 (23%)
Query: 83 RRRSQCCPGY--YESGDFCI-PLCTEECVHGRCVSPDTCHCEPGWGGPDC----SSGCDS 135
R + CCPG+ + C+ P+C C G C P+ C C G P C SGC
Sbjct: 63 RFHAYCCPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGTLAPSCGVSRGSGCS- 121
Query: 136 DHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRC-EELCAPGTHGKG-CQLP--CQC 191
C NG C +C+C G+ G C + +C G H G C P C C
Sbjct: 122 ----------VSCMNGGTCR--GASCLCQKGYTGTVCGQPICDRGCHNGGRCIGPNRCAC 169
Query: 192 RHG-----ASCDPRAGECL-------CAPGYTGVYCE----------------ELCP--- 220
+G D R G C C TG+ C ELCP
Sbjct: 170 VYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAWGLPCELCPAQP 229
Query: 221 --------PGSHGAHCELRCPCQ------NGGTCHHITG--ECACPPGW----TGAVC-- 258
P H C+ CQ GG+C ++ G C CP G + A C
Sbjct: 230 HPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGHRLSDSSAACED 289
Query: 259 --AQPCPPGTFGQNCSQDCPCHH-GGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQ-- 313
A C FG C+ D H+ QC G+C AG + + C P GS FQ
Sbjct: 290 YRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRC-WAAGPVPELCP---PRGSNEFQQL 345
Query: 314 CSQHCDCHNG--GQCSPTTGACECEPGYKGPRCQERLCPEGLH-------GPGCTLPCPC 364
C+Q G G G G P RL P G GPG +
Sbjct: 346 CAQRLPLLPGHPGLFPGLLGF--GSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTA 403
Query: 365 DADNTIS-CHPVTGAC---TCQPGWSGHHCNESCPVGYYGD---GC--QLPCT---CQNG 412
+ TI C T C C P S + C C VGY D C CT C +G
Sbjct: 404 TLNQTIDICRHFTNLCLNGRCLPTPSSYRC--ECNVGYTQDVRGECIDVDECTSSPCHHG 461
Query: 413 ADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCK 468
DC +I G C C PGF +C +C G C +GS C C
Sbjct: 462 -DCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHL---GRCVNTEGSFQCVCN 517
Query: 469 EGWQGLDCTLPCPSGTWGLNCNESCT---CANGAACSPIDG--SCSCTPGWLGDTCELPC 523
G++ P G ++ NE T C NG C DG SC C PG+ L
Sbjct: 518 AGFE------LSPDGKNCVDHNECATSTMCVNG-VCLNEDGSFSCLCKPGF------LLA 564
Query: 524 PDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCEN 583
P G + C + +C C V GHC G +C G G C V +
Sbjct: 565 PGGHY---CMDIDECQTPGIC--VNGHCTNTEGSFRCQCLGGLAVGTDGRVC-VDTHVRS 618
Query: 584 GGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSR------------- 630
+ E GS CA F G + + C HG +PC LC
Sbjct: 619 TCYGAIEKGS--CARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGI 676
Query: 631 -------------PCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSP 677
P +G+CE L G +CN G G+DC + CA N
Sbjct: 677 TTDGRDINECALDPEVCANGVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCD 736
Query: 678 IDGSCQCFPGWIGKDCSQACPPG--FWGPA--CFHACSCHNGASCS------AEDGACHC 727
+G CQ PG S +CPPG FW C C + S A C C
Sbjct: 737 -NGWCQNSPG----SYSCSCPPGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGSYTCKC 791
Query: 728 TPGW----TGLFCTQRCPAAFFGKDCGRVCQCQ-NGASCDHISGKCTCRTGFT-GQHCEQ 781
PG +G FC + K C+ GAS + +C G G CE+
Sbjct: 792 GPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGAS---LRSECCATLGAAWGSPCER 848
Query: 782 -----RCAPG---TFGYGCQQLCECMN------NSTCDHVTGT--CYCSPG 816
CA G G C + EC + N C + G+ C C G
Sbjct: 849 CEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEG 899
Score = 129 bits (323), Expect = 2e-29
Identities = 209/748 (27%), Positives = 259/748 (34%), Gaps = 194/748 (25%)
Query: 148 CQNGALCNPITGA-CVCAAGFRGWRCEELCAPGTHGKGCQL-PCQCRHGASCD-PRAGEC 204
C +G N + C CA GF E C T C++ P C G + P + EC
Sbjct: 997 CTHGTCRNTVGSFHCACAGGFALDAQERNC---TDIDECRISPDLCGQGTCVNTPGSFEC 1053
Query: 205 LCAPGY-TGVYCEELCPPGSHGAHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQP 261
C PGY +G + C A L C GGTC + G +C CPPG
Sbjct: 1054 ECFPGYESGFMLMKNCMDVDECARDPLLC---RGGTCTNTDGSYKCQCPPGHELTAKGTA 1110
Query: 262 CPPGTFGQNCS-QDCPCHHGGQCDHVTG--QCHCTAGYMGDRCQEECPFGSFGFQCSQHC 318
C CS D C HG QC +V G QC C AG+ ++ C C
Sbjct: 1111 CEDI---DECSLSDGLCPHG-QCVNVIGAFQCSCHAGFQSTPDRQGCVD-------INEC 1159
Query: 319 DCHNGG---QCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCH 373
NGG C T G+ C C GY L P+G C C+ +N C
Sbjct: 1160 RVQNGGCDVHCINTEGSYRCSCGQGYS-------LMPDGR---ACADVDECE-ENPRVCD 1208
Query: 374 PVTGACTCQPGWSGHHCNESCPVGYYG----------DGCQL-PCTCQNGADCHSITGG- 421
G CT PG GH C C G+ D C L P C +G DC + G
Sbjct: 1209 Q--GHCTNMPG--GHRC--LCYDGFMATPDMRTCVDVDECDLNPHICLHG-DCENTKGSF 1261
Query: 422 -CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPC 480
C C G+M A C S + C GG
Sbjct: 1262 VCHCQLGYMVRKGATGC---------SDVDECEVGGH----------------------- 1289
Query: 481 PSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDC-S 539
NC+ +C N P SC C PGW+GD G C + +C S
Sbjct: 1290 -------NCDSHASCLN----IPGSFSCRCLPGWVGD-----------GFECHDLDECVS 1327
Query: 540 HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPN--CSVSCSC-ENGGSCSPEDGSCEC 596
C P G C + G RC TC G G C C EN C ++G C
Sbjct: 1328 QEHRCSP-RGDCLNVPG--SYRC--TCRQGFAGDGFFCEDRDECAENVDLC--DNGQCLN 1380
Query: 597 APGFRGPLCQRICPPGF---YGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQV 653
APG G C+ C GF H Q C + G CE LPG +CN
Sbjct: 1381 APG--GYRCE--CEMGFDPTEDHRACQDVDECAQGNLCAF---GSCENLPGMFRCICN-- 1431
Query: 654 CAGGY----FGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACF-- 707
GGY G +C + CA+ C I+G C PG C Q G C
Sbjct: 1432 --GGYELDRGGGNCTDINECADPVNC--INGVCINTPGSYLCSCPQDFELNPSGVGCVDT 1487
Query: 708 HACSC--------HNGASCSAEDG------ACHCTPGWTGLFCTQRCPAAFFGKDCGRVC 753
A +C +G SCSAE G +C C+ G + CP A + +C
Sbjct: 1488 RAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMA-NTTEYRTLC 1546
Query: 754 QCQNG-------------ASCDHISGKC---TCRTGFTGQHCEQRCAPG----TFGYGCQ 793
G C + G C C F CE C PG C+
Sbjct: 1547 PGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCE--CPPGYHLSEHTRICE 1604
Query: 794 QLCECMNNS------TCDHVTG--TCYC 813
+ EC +S TC + G TC C
Sbjct: 1605 DIDECSTHSGICGPGTCYNTLGNYTCVC 1632
Score = 127 bits (318), Expect = 7e-29
Identities = 238/943 (25%), Positives = 304/943 (32%), Gaps = 253/943 (26%)
Query: 85 RSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSN 144
R +C G+ + D +EC G + +C PG C+ G + D G +C++
Sbjct: 1386 RCECEMGFDPTEDHRACQDVDECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTD 1445
Query: 145 RCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGC----------QLPCQCRHG 194
+C + C I G C+ G C + G GC + + G
Sbjct: 1446 INECADPVNC--INGVCINTPGSYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSG 1503
Query: 195 ASCDPRAG------ECLCAPGYTGVYCEELCP-----------PGSHG------------ 225
SC G C C+ G ELCP PG G
Sbjct: 1504 ISCSAEIGVGVTRASCCCSLGRAWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILED 1563
Query: 226 -AHC-ELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHG- 280
C EL CQ GG C + G +C CPPG+ + + C +C H G
Sbjct: 1564 IDECQELPGLCQ-GGDCVNTFGSFQCECPPGYHLSEHTRICED-------IDECSTHSGI 1615
Query: 281 ---GQCDHVTGQ--CHCTAGYM--------------------GDRCQEECPFGSFGFQCS 315
G C + G C C A Y+ CQ E F C
Sbjct: 1616 CGPGTCYNTLGNYTCVCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMC- 1674
Query: 316 QHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL------PCPCDADNT 369
C +N GQ CE P P Q LC G PG P D
Sbjct: 1675 --CCSYNIGQA--WNRPCEACPTPISPDYQ-ILC--GNQAPGFLTDIHTGKPLDIDECGE 1727
Query: 370 ISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPC-----------TCQNGADCHSI 418
I G C Q G C CP G+ + L C CQ ADC +I
Sbjct: 1728 IPAICANGICINQIG--SFRC--ECPAGFNYNSILLACEDVDECGSRESPCQQNADCINI 1783
Query: 419 TGG--CTCAPGFMGEVCAVSCAAGTYGPN-CSSICSCNNGGTCSPVDGS--CTCKEGWQ- 472
G C C G+ +S G N C I + + G C +GS C C G+Q
Sbjct: 1784 PGSYRCKCTRGY-----KLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQA 1838
Query: 473 GLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGS--CSCTPGWL----GDTCELPCPDG 526
D TL ++ + C NG C I GS C C PG++ GD +
Sbjct: 1839 SADQTL-----CMDIDECDRQPCGNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTT 1892
Query: 527 TFGLNC----------SEHCDCSH-----ADGCDPV-TGHCCCLAGWT----------GI 560
G C S HC C ADG + V T C LAG
Sbjct: 1893 LVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEGSF 1952
Query: 561 RCDSTCPPG--------------RWGPNCSVSCSCENGGSCSPEDGSCECAPGF----RG 602
RC CPPG PN + +C N SP C C PGF G
Sbjct: 1953 RC--ICPPGFQVQSDHCIDIDECSEEPNLCLFGTCTN----SPGSFQCLCPPGFVLSDNG 2006
Query: 603 PLC----QRICPPGFYGHGCAQPCPL------CVHSSRPCHHISGICECLPGFSGALCNQ 652
C Q C F C+ P C S RP CE P A +
Sbjct: 2007 HRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQE 2066
Query: 653 VCAGGYFG-----------QDCAQLCSCANNGTCSPIDGS--CQCFPGW----------- 688
+C G+ +CA+ NG C DGS C+C G+
Sbjct: 2067 LCPFGHGAVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVD 2126
Query: 689 -----IGKDCSQ-ACPPGFWGPACFHACSCHNGASCSAED------------GACHCTPG 730
+G C Q C G C A G + ED CH T G
Sbjct: 2127 TDECSVGHPCGQGTCTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCAFRCHNTEG 2186
Query: 731 WTGLFCTQRCPAAFFGKDCGRVC----QCQNGASCDHISG-KCTCRTGFTGQHCE--QRC 783
CT CPA + ++ G +C +C +G H G +C G C R
Sbjct: 2187 --SYLCT--CPAGYTLREDGAMCRDVDECADGQQDCHARGMECKNLIGTFACVCPPGMRP 2242
Query: 784 APGTFGYGCQQLCEC------MNNSTCDHVTGT--CYCSPGFK 818
PG+ G GC EC N C + G+ C C GF+
Sbjct: 2243 LPGS-GEGCTDDNECHAQPDLCVNGRCVNTAGSFRCDCDEGFQ 2284
Score = 124 bits (312), Expect = 4e-28
Identities = 223/894 (24%), Positives = 298/894 (33%), Gaps = 244/894 (27%)
Query: 85 RSQCCPGYYES-GDFCIPL--CTE---ECVHGRCVSPD---TCHCEPGWGGPDCSSGC-D 134
R +C GY S G C+ C E C HG C+ + C C G+ + C D
Sbjct: 1788 RCKCTRGYKLSPGGACVGRNECREIPNVCSHGDCMDTEGSYMCLCHRGFQASADQTLCMD 1847
Query: 135 SDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPG---THGKGCQLPCQC 191
D +R C NG C I G+ C LC PG TH C +C
Sbjct: 1848 IDE-----CDRQPCGNGT-CKNIIGSYNC-----------LCFPGFVVTHNGDCVDFDEC 1890
Query: 192 RHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQN------GGTCHHITG 245
R G CL G C++ + G +C C + GTC ++ G
Sbjct: 1891 TTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLPGTCQNLEG 1950
Query: 246 E--CACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTG--QCHCTAGYM---- 297
C CPPG+ V + C CS++ G C + G QC C G++
Sbjct: 1951 SFRCICPPGFQ--VQSDHCIDI---DECSEEPNLCLFGTCTNSPGSFQCLCPPGFVLSDN 2005
Query: 298 GDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPG-----------YKGPRCQE 346
G RC + F + C + T C PG +G +
Sbjct: 2006 GHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQ 2065
Query: 347 RLCPEGLHGPGCTLPCPCDADNTIS-CHPVTGACT---CQPGWSGHHCNESCPVGYY--- 399
LCP G HG +P P D+ ++ C G CT C C CP GY
Sbjct: 2066 ELCPFG-HG---AVPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCE--CPFGYSLDF 2119
Query: 400 -------GDGCQLPCTCQNGADCHSITGG--CTCAPGFMG---------EVCAVS---CA 438
D C + C G C ++ GG C CA GF + C+++ CA
Sbjct: 2120 TGINCVDTDECSVGHPCGQGT-CTNVIGGFECACADGFEPGLMMTCEDIDECSLNPLLCA 2178
Query: 439 AGTYGPNCSSICSC-------NNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNE 491
+ S +C+C +G C VD C +G Q DC
Sbjct: 2179 FRCHNTEGSYLCTCPAGYTLREDGAMCRDVD---ECADGQQ--DCH-------------- 2219
Query: 492 SCTCANGAACSPIDGS--CSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTG 549
A G C + G+ C C PG P P G C++ +C HA V G
Sbjct: 2220 ----ARGMECKNLIGTFACVCPPGMR------PLPGS--GEGCTDDNEC-HAQPDLCVNG 2266
Query: 550 HCCCLAGWTGIRCDSTCPPG---------RWGPNCS--VSCSCENGGSCSPEDGSCECAP 598
C AG CD P R GP + + C + S S EC
Sbjct: 2267 RCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCC 2326
Query: 599 GFR---GPLCQRICP-PGFYGHGCAQPCPLCVHSSR---------PCHHISGIC---ECL 642
G GP C+ +CP PG + LC H S C ++ +C EC+
Sbjct: 2327 GGGRGWGPRCE-LCPLPGTSAYR-----KLCPHGSGYTAEGRDVDECRMLAHLCAHGECI 2380
Query: 643 PGFSGALCNQVCAGGYFGQDCAQLC----SCAN-----NGTCSPIDGS--CQCFPGWI-- 689
C+ C GY A C C+ C GS C C G++
Sbjct: 2381 NSLGSFRCH--CQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLE 2438
Query: 690 --GKDCSQA------------------------CPPGFWGPACFHACSCHNGASCSAEDG 723
G+ C CPPGF H +C + CSA+ G
Sbjct: 2439 EDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQ----HHQACFDNDECSAQPG 2494
Query: 724 AC------HCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDH-----ISG-KCTCR 771
C H TPG C Q G C V +C C H + G +C+C
Sbjct: 2495 PCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHGCQNQLGGYRCSCP 2554
Query: 772 TGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTC---YCSPGFKGIRC 822
GFT QH Q +C++ + C TC C G RC
Sbjct: 2555 QGFT-QH--------------SQWAQCVDENECALSPPTCGSASCRNTLGGFRC 2593
Score = 112 bits (279), Expect = 2e-24
Identities = 236/1004 (23%), Positives = 310/1004 (30%), Gaps = 331/1004 (32%)
Query: 76 RGLRTMYRRRSQCCPGYYES--GDFCIPL--CTEE-CVHGRCVS-PDTCHCEPGWGGPDC 129
R L T R +C GY + G+ CI + CT C HG CV+ P T HC C
Sbjct: 423 RCLPTPSSYRCECNVGYTQDVRGE-CIDVDECTSSPCHHGDCVNIPGTYHCR-------C 474
Query: 130 SSGCDSDHWGPHCSNRCQC-QNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLP 188
G + C + +C +G LC+ G CV G C GK C
Sbjct: 475 YPGFQATPTRQACVDVDECIVSGGLCH--LGRCVNTEGSFQCVCNAGFELSPDGKNCVDH 532
Query: 189 CQCRHGASC-------DPRAGECLCAPGYT----GVYC---EELCPPG-SHGAHC----- 228
+C C + + CLC PG+ G YC +E PG HC
Sbjct: 533 NECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVNGHCTNTEG 592
Query: 229 ELRCPCQNG----------------GTCHHITGECACPPGWTGAVCAQPC----PPGTFG 268
RC C G TC+ + +C + G V C P FG
Sbjct: 593 SFRCQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFG 652
Query: 269 QNCSQDCP----------CHHG----------------------GQCDHVTG--QCHCTA 294
+ C Q CP C G G C+++ G +C C
Sbjct: 653 EPC-QLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCANGVCENLRGSYRCVCNL 711
Query: 295 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH 354
GY ++C +C+ + + G C + G+ C CP G H
Sbjct: 712 GYEAGASGKDCTDVD---ECALNSLLCDNGWCQNSPGSYSCS------------CPPGFH 756
Query: 355 GPGCTLPCPCDADNTISCHPVTGACT---------CQPGW----SGHHCNES-------- 393
T C D D +S V+G C C PG SG C +S
Sbjct: 757 FWQDTEICK-DVDECLSSPCVSGVCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTCWLK 815
Query: 394 -----CPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSS 448
C V G + C GA S C P CA A T G C
Sbjct: 816 IQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPA-----CARGFARMT-GVTCDD 869
Query: 449 ICSCNN------GGTCSPVDGS--CTCKEG---------------------WQGLDC--T 477
+ C + G C GS C C EG W +C T
Sbjct: 870 VNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVT 929
Query: 478 LP---------CPSGT-WGLNCNESCT----------CANGAACSPID------------ 505
LP C G WG+ C E+C C G + D
Sbjct: 930 LPGKYRMDVCCCSIGAVWGVEC-EACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVN 988
Query: 506 -----------GSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGC---DPVTGHC 551
G+C T G C G F L+ E +C+ D C + G
Sbjct: 989 ECKVFPGLCTHGTCRNTVGSFHCACA-----GGFALDAQER-NCTDIDECRISPDLCGQG 1042
Query: 552 CCLAGWTGIRCDSTCPPGRWG-----PNCSVSCSCEN------GGSCSPEDGS--CECAP 598
C+ C+ C PG NC C GG+C+ DGS C+C P
Sbjct: 1043 TCVNTPGSFECE--CFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYKCQCPP 1100
Query: 599 GF----RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI--CECLPGFSGALCNQ 652
G +G C+ I C+ LC H C ++ G C C GF Q
Sbjct: 1101 GHELTAKGTACEDI-------DECSLSDGLCPHGQ--CVNVIGAFQCSCHAGFQSTPDRQ 1151
Query: 653 VCAG----------------------------GYF----GQDCAQLCSCANN------GT 674
C GY G+ CA + C N G
Sbjct: 1152 GCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGH 1211
Query: 675 CSPIDGS--CQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDGACHCTPGW- 731
C+ + G C C+ G++ + C H C H + CHC G+
Sbjct: 1212 CTNMPGGHRCLCYDGFMATPDMRTCVDVDECDLNPHIC-LHGDCENTKGSFVCHCQLGYM 1270
Query: 732 -----TGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGFTGQHCEQRCAPG 786
TG C C + ASC +I G +CR C PG
Sbjct: 1271 VRKGATGCSDVDECEVGGHN--------CDSHASCLNIPGSFSCR-----------CLPG 1311
Query: 787 TFGYG--CQQLCECMN-------NSTCDHVTGT--CYCSPGFKG 819
G G C L EC++ C +V G+ C C GF G
Sbjct: 1312 WVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCRQGFAG 1355
Score = 72.8 bits (177), Expect = 2e-12
Identities = 102/428 (23%), Positives = 134/428 (31%), Gaps = 113/428 (26%)
Query: 107 CVHGRCVSPD---TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNP---ITGA 160
CV+GRCV+ C C+ G+ + C GP + Q +L + +T A
Sbjct: 2263 CVNGRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRA 2322
Query: 161 CVCAAGFRGW--RCEELCAPGT--------HGKG----------CQLPCQ-CRHGASCDP 199
C G RGW RCE PGT HG G C++ C HG +
Sbjct: 2323 ECCCGGGRGWGPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAHGECINS 2382
Query: 200 RAG-ECLCAPGYT----GVYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWT 254
C C GYT C ++ C C G C+CP G+
Sbjct: 2383 LGSFRCHCQAGYTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFL------CSCPRGYL 2436
Query: 255 ----GAVCAQ------------------------PCPPG--TFGQNCSQDCPCH-HGGQC 283
G C CPPG Q C + C G C
Sbjct: 2437 LEEDGRTCKDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDNDECSAQPGPC 2496
Query: 284 DHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPR 343
G CH T G C + S G C +C +C C+ G R
Sbjct: 2497 G-AHGHCHNTPGSFRCECHQGFTLVSSGHGCEDVNECDGPHRCQHG-----CQNQLGGYR 2550
Query: 344 CQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGC 403
C CP+G C + + +S P G+ +C+ G C
Sbjct: 2551 CS---CPQGFTQHSQWAQCVDENECALS-PPTCGSASCRNTLGGFRC------------- 2593
Query: 404 QLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDG 463
C +G D GGC V AG GP CS C+ GG
Sbjct: 2594 ----VCPSGFDFDQALGGCQ----------EVDECAGRRGP-CSYSCANTPGGFL----- 2633
Query: 464 SCTCKEGW 471
C C +G+
Sbjct: 2634 -CGCPQGY 2640
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 149 bits (377), Expect = 1e-35
Identities = 118/386 (30%), Positives = 149/386 (38%), Gaps = 98/386 (25%)
Query: 83 RRRSQCCPGY---YESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWG 139
R C PG+ Y + C+P C E+ HG C P C C GW G C
Sbjct: 207 RGEKVCNPGWKGPYCTEPICLPGCDEQ--HGFCDKPGECKCRVGWQGRYCD--------- 255
Query: 140 PHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDP 199
C C +G P C C G+ G C + TH K C++GA+C
Sbjct: 256 -ECIRYPGCLHGTCQQP--WQCNCQEGWGGLFCNQDLNYCTHHK------PCKNGATC-T 305
Query: 200 RAGE----CLCAPGYTGVYCE---ELCPPGSHGAHCELRCPCQNGGTCHHITG--ECACP 250
G+ C C PGYTG CE + C P PC+NGG+C + C CP
Sbjct: 306 NTGQGSYTCSCRPGYTGATCELGIDECDPS----------PCKNGGSCTDLENSYSCTCP 355
Query: 251 PGWTGAVC---AQPCPPGTFGQNCSQDCPCHHGGQC-DHVTG--QCHCTAGYMGDRCQEE 304
PG+ G +C A C G PC +GG+C D G C C GY G C+++
Sbjct: 356 PGFYGKICELSAMTCADG----------PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKK 405
Query: 305 CPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKGPRCQERLCPEGLHGPGCTLPC 362
+ CS C NG +C A C C+ G+ G C
Sbjct: 406 IDY------CSS-SPCSNGAKCVDLGDAYLCRCQAGFSGRHCD----------------- 441
Query: 363 PCDADNTISC--HPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITG 420
DN C P TC+ G + C +CP GY G C P + A CH+
Sbjct: 442 ----DNVDDCASSPCANGGTCRDGVNDFSC--TCPPGYTGRNCSAPVSRCEHAPCHN--- 492
Query: 421 GCTCAPGFMGEVCAVSCAAGTYGPNC 446
G TC VC CA G GPNC
Sbjct: 493 GATCHERGHRYVC--ECARGYGGPNC 516
Score = 144 bits (363), Expect = 4e-34
Identities = 125/433 (28%), Positives = 164/433 (37%), Gaps = 118/433 (27%)
Query: 266 TFGQNCSQDCPCHHGGQCD-HVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGG 324
T G+ SQD H G+ D + + C Y G+ C C F H C G
Sbjct: 154 TVGEEWSQDL--HSSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDDAFG---HFTCGERG 208
Query: 325 QCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPG 384
+ C PG+KGP C E +C G CD + P G C C+ G
Sbjct: 209 EKV-------CNPGWKGPYCTEPICLPG-----------CDEQHGFCDKP--GECKCRVG 248
Query: 385 WSGHHCNE------------------SCPVGYYGDGCQLP---CT----CQNGADCHSIT 419
W G +C+E +C G+ G C CT C+NGA C +
Sbjct: 249 WQGRYCDECIRYPGCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTG 308
Query: 420 GG---CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGL 474
G C+C PG+ G C + P C NGG+C+ ++ S CTC G+ G
Sbjct: 309 QGSYTCSCRPGYTGATCELGIDECDPSP-------CKNGGSCTDLENSYSCTCPPGFYGK 361
Query: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPI-DGSCSCTPGWLGDTCELPCPDGTFGLNCS 533
C L + C + C NG CS DG SC CP G G NC
Sbjct: 362 ICELSA------MTCADG-PCFNGGRCSDSPDGGYSCR-----------CPVGYSGFNCE 403
Query: 534 EHCD------CSHADGCDPVTGH--CCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGG 585
+ D CS+ C + C C AG++G CD +C+ S C NGG
Sbjct: 404 KKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVD------DCA-SSPCANGG 456
Query: 586 SCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCH-----HISG--- 637
+C C CPPG+ G C+ P C H+ PCH H G
Sbjct: 457 TCRDGVNDFSCT-----------CPPGYTGRNCSAPVSRCEHA--PCHNGATCHERGHRY 503
Query: 638 ICECLPGFSGALC 650
+CEC G+ G C
Sbjct: 504 VCECARGYGGPNC 516
Score = 139 bits (351), Expect = 1e-32
Identities = 123/405 (30%), Positives = 152/405 (37%), Gaps = 118/405 (29%)
Query: 262 CPPGTFGQNCSQDCPCHHGGQCDHVT----GQCHCTAGYMGDRCQEECPFGSFGFQCSQH 317
C +G+ CS C H T G+ C G+ G C E C
Sbjct: 179 CDEHYYGEGCSVFCRPRDDA-FGHFTCGERGEKVCNPGWKGPYCTEPI--------CLPG 229
Query: 318 CDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTG 377
CD +G P G C+C G++G R C E + PGC L C
Sbjct: 230 CDEQHGFCDKP--GECKCRVGWQG-----RYCDECIRYPGC-LHGTCQQP---------W 272
Query: 378 ACTCQPGWSGHHCNE---------------------------SCPVGYYGDGCQL----- 405
C CQ GW G CN+ SC GY G C+L
Sbjct: 273 QCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDEC 332
Query: 406 -PCTCQNGADCHSITG--GCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCS-PV 461
P C+NG C + CTC PGF G++C +S GP C NGG CS
Sbjct: 333 DPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGP-------CFNGGRCSDSP 385
Query: 462 DGSCTCKEGWQGLDCTLPCPSGTWGLNCNE------SCTCANGAACSPIDGSCSCTPGWL 515
DG +C+ CP G G NC + S C+NGA C +D L
Sbjct: 386 DGGYSCR-----------CPVGYSGFNCEKKIDYCSSSPCSNGAKC--VD---------L 423
Query: 516 GDTCELPCPDGTFGLNCSEHC-DCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPN 574
GD C G G +C ++ DC+ + P C G C TCPPG G N
Sbjct: 424 GDAYLCRCQAGFSGRHCDDNVDDCASS----PCANGGTCRDGVNDFSC--TCPPGYTGRN 477
Query: 575 CSVSCS------CENGGSCSPEDGS---CECAPGFRGPLCQRICP 610
CS S C NG +C E G CECA G+ GP CQ + P
Sbjct: 478 CSAPVSRCEHAPCHNGATCH-ERGHRYVCECARGYGGPNCQFLLP 521
Score = 124 bits (312), Expect = 4e-28
Identities = 93/301 (30%), Positives = 115/301 (38%), Gaps = 87/301 (28%)
Query: 107 CVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALC-NPITGACVCAA 165
C+HG C P C+C+ GWGG C+ + +C++ C+NGA C N G+ C+
Sbjct: 263 CLHGTCQQPWQCNCQEGWGGLFCNQDLN------YCTHHKPCKNGATCTNTGQGSYTCS- 315
Query: 166 GFRGWRCEELCAPGTHGKGCQL------PCQCRHGASCDPRAGECLCAPGYTGVYCEELC 219
C PG G C+L P C++G SC C C
Sbjct: 316 ----------CRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCT-----------C 354
Query: 220 PPGSHGAHCELRC------PCQNGGTCHHITG---ECACPPGWTGAVCAQP--------- 261
PPG +G CEL PC NGG C C CP G++G C +
Sbjct: 355 PPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPC 414
Query: 262 ----------------CPPGTFGQNCS---QDC---PCHHGGQC-DHVTG-QCHCTAGYM 297
C G G++C DC PC +GG C D V C C GY
Sbjct: 415 SNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYT 474
Query: 298 GDRCQEECPFGSFGFQCSQHCDCHNGGQCSPT--TGACECEPGYKGPRCQERLCPEGLHG 355
G C S +H CHNG C CEC GY GP CQ L PE G
Sbjct: 475 GRNC-------SAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQ-FLLPELPPG 526
Query: 356 P 356
P
Sbjct: 527 P 527
Score = 120 bits (300), Expect = 9e-27
Identities = 119/448 (26%), Positives = 156/448 (34%), Gaps = 130/448 (29%)
Query: 480 CPSGTWGLNCNESCTCANGA----ACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEH 535
C +G C+ C + A C G C PGW G C P C
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGE-RGEKVCNPGWKGPYCTEPI--------CLPG 229
Query: 536 CDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCE 595
CD H CD G C C GW G CD C C +G P C
Sbjct: 230 CDEQHGF-CDK-PGECKCRVGWQGRYCDE----------CIRYPGCLHGTCQQP--WQCN 275
Query: 596 CAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHI---------SGICECLPGFS 646
C G+ G C Q C H +PC + S C C PG++
Sbjct: 276 CQEGWGGLFCN-------------QDLNYCTHH-KPCKNGATCTNTGQGSYTCSCRPGYT 321
Query: 647 GALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC 706
GA C G D C N G+C+ ++ S C CPPGF+G C
Sbjct: 322 GATCE-------LGIDECDPSPCKNGGSCTDLENSYSC-----------TCPPGFYGKIC 363
Query: 707 ---FHACS---CHNGASCS-AEDG--ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQN 757
C+ C NG CS + DG +C C G++G C ++ D C N
Sbjct: 364 ELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKI-------DYCSSSPCSN 416
Query: 758 GASCDHISGK--CTCRTGFTGQHCEQR-------------------------CAPGTFGY 790
GA C + C C+ GF+G+HC+ C PG G
Sbjct: 417 GAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Query: 791 GCQ---QLCE---CMNNSTCDHVTG---TCYCSPGFKGIRCDQAALMMEELNP------Y 835
C CE C N +TC H G C C+ G+ G C ++ EL P
Sbjct: 477 NCSAPVSRCEHAPCHNGATC-HERGHRYVCECARGYGGPNCQ---FLLPELPPGPAVVDL 532
Query: 836 TKISPALGAERHSVGAVTGIMLLLFLIV 863
T+ G V G++L+L L++
Sbjct: 533 TEKLEGQGGPFPWVAVCAGVILVLMLLL 560
Score = 87.0 bits (214), Expect = 8e-17
Identities = 68/232 (29%), Positives = 92/232 (39%), Gaps = 53/232 (22%)
Query: 608 ICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQ-- 665
+C +YG GC+ C RP G C G +VC G+ G C +
Sbjct: 178 VCDEHYYGEGCSVFC-------RPRDDAFGHFTC-----GERGEKVCNPGWKGPYCTEPI 225
Query: 666 -LCSC-ANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHNGASCSAEDG 723
L C +G C G C+C GW G+ C + P C H +C +
Sbjct: 226 CLPGCDEQHGFCDK-PGECKCRVGWQGRYCDECIRY----PGCLHG-------TCQ-QPW 272
Query: 724 ACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHI---SGKCTCRTGFTGQHCE 780
C+C GW GLFC Q C C+NGA+C + S C+CR G+TG CE
Sbjct: 273 QCNCQEGWGGLFCNQDL------NYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCE 326
Query: 781 ---QRCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCDQAAL 827
C P C N +C + +C C PGF G C+ +A+
Sbjct: 327 LGIDECDPS----------PCKNGGSCTDLENSYSCTCPPGFYGKICELSAM 368
Score = 68.6 bits (166), Expect = 3e-11
Identities = 61/212 (28%), Positives = 77/212 (36%), Gaps = 78/212 (36%)
Query: 54 CTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCV 113
CTD+ N + CT C PG+Y G C L C G C
Sbjct: 343 CTDLENSYSCT-----------------------CPPGFY--GKIC-ELSAMTCADGPCF 376
Query: 114 -------SPD---TCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA--C 161
SPD +C C G+ G +C D +CS+ C NGA C + A C
Sbjct: 377 NGGRCSDSPDGGYSCRCPVGYSGFNCEKKID------YCSSS-PCSNGAKCVDLGDAYLC 429
Query: 162 VCAAGFRGWRCEE-------------------------LCAPGTHGKGCQLP---CQ--- 190
C AGF G C++ C PG G+ C P C+
Sbjct: 430 RCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP 489
Query: 191 CRHGASCDPRAGE--CLCAPGYTGVYCEELCP 220
C +GA+C R C CA GY G C+ L P
Sbjct: 490 CHNGATCHERGHRYVCECARGYGGPNCQFLLP 521
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.139 0.516
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,575,212
Number of Sequences: 37866
Number of extensions: 3617772
Number of successful extensions: 29561
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 154
Number of HSP's successfully gapped in prelim test: 446
Number of HSP's that attempted gapping in prelim test: 7786
Number of HSP's gapped (non-prelim): 6033
length of query: 1044
length of database: 18,247,518
effective HSP length: 112
effective length of query: 932
effective length of database: 14,006,526
effective search space: 13054082232
effective search space used: 13054082232
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.