Guide to the Human Genome
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Name: NOTCH2 Sequence: fasta or formatted (2471aa) NCBI GI: 24041035
Description:

notch 2 preproprotein

Referenced in:

Notch Pathway

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        171           4
 C cysteine            9.8        243           2
 D aspartate           6.2        152           2
 E glutamate           5.2        129           2
 F phenylalanine       2.4         59           1
 G glycine             8.9        219           3
 H histidine           3.1         76           3
 I isoleucine          3.2         79           2
 K lysine              2.9         72           2
 L leucine             6.9        171           4
 M methionine          1.9         47           2
 N asparagine          5.8        143           2
 P proline             7.3        181           2
 Q glutamine           4.8        118           2
 R arginine            3.7         92           2
 S serine              7.3        181           4
 T threonine           5.5        135           2
 V valine              4.8        119           2
 W tryptophan          0.8         19           1
 Y tyrosine            2.6         65           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   notch 2 preproprotein 
NOTCH1                0.532   notch1 preproprotein 
NOTCH3                0.370   Notch homolog 3 
NOTCH4                0.229   notch4 preproprotein 
EYS                   0.106   eyes shut homolog isoform 1 
JAG1                  0.093   jagged 1 precursor 
FBN1                  0.092   fibrillin 1 precursor 
FBN2                  0.090   fibrillin 2 precursor 
FBN3                  0.088   fibrillin 3 precursor 
JAG2                  0.088   jagged 2 isoform a precursor 
NOTCH2NL              0.086   Notch homolog 2 N-terminal like protein 
JAG2                  0.081   jagged 2 isoform b precursor 
SNED1                 0.080   6720455I24Rik homolog 
MEGF6                 0.071   EGF-like-domain, multiple 3 
CRB1                  0.063   crumbs homolog 1 precursor 
CRB2                  0.056   crumbs homolog 2 
DNER                  0.052   delta-notch-like EGF repeat-containing transmembran...
MEGF10                0.047   multiple EGF-like-domains 10 
MEGF11                0.047   multiple EGF-like-domains 11 
DLL1                  0.046   delta-like 1 
SVEP1                 0.046   polydom 
LTBP2                 0.044   latent transforming growth factor beta binding protei...
LTBP4                 0.043   latent transforming growth factor beta binding prot...
LTBP4                 0.043   latent transforming growth factor beta binding prot...
LTBP4                 0.043   latent transforming growth factor beta binding prot...
DLL4                  0.042   delta-like 4 protein precursor 
TNXB                  0.042   tenascin XB isoform 1 precursor 
LTBP1                 0.039   latent transforming growth factor beta binding prote...
LTBP1                 0.039   latent transforming growth factor beta binding prote...
TNC                   0.038   tenascin C precursor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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