Guide to the Human Genome
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Search of human proteins with 18105032

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
         (680 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]         1484   0.0  
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]               711   0.0  
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]       704   0.0  
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]       704   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      463   e-130
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   461   e-130
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   461   e-129
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     460   e-129
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   459   e-129
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     452   e-127
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   446   e-125
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   446   e-125
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     446   e-125
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        442   e-124
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    438   e-123
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    436   e-122
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   436   e-122
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   436   e-122
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   436   e-122
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      434   e-121
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              431   e-120
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   429   e-120
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   429   e-120
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   429   e-120
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               428   e-120
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         426   e-119
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   426   e-119
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   423   e-118
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...   422   e-118
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   422   e-118

>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 1484 bits (3843), Expect = 0.0
 Identities = 680/680 (100%), Positives = 680/680 (100%)

Query: 1   MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQG 60
           MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQG
Sbjct: 1   MLPQIPFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQG 60

Query: 61  TPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGER 120
           TPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGER
Sbjct: 61  TPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGER 120

Query: 121 GPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPG 180
           GPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPG
Sbjct: 121 GPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPG 180

Query: 181 VPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFP 240
           VPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFP
Sbjct: 181 VPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFP 240

Query: 241 GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK 300
           GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK
Sbjct: 241 GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK 300

Query: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360
           PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP
Sbjct: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360

Query: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL 420
           KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL
Sbjct: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL 420

Query: 421 PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI 480
           PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI
Sbjct: 421 PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI 480

Query: 481 ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLV 540
           ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLV
Sbjct: 481 ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLV 540

Query: 541 SANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFS 600
           SANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFS
Sbjct: 541 SANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFS 600

Query: 601 YHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESN 660
           YHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESN
Sbjct: 601 YHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQLPNAESN 660

Query: 661 GLYSSEYVHSSFSGFLVAPM 680
           GLYSSEYVHSSFSGFLVAPM
Sbjct: 661 GLYSSEYVHSSFSGFLVAPM 680


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score =  711 bits (1834), Expect = 0.0
 Identities = 347/629 (55%), Positives = 406/629 (64%), Gaps = 10/629 (1%)

Query: 59  QGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPG 118
           +G PGPPG  GPRG PGP G PGKPG G PGL G+PG  GPPG S +GK G PGLPGK G
Sbjct: 76  KGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVG 135

Query: 119 ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178
             G  G +G+ G  G  G RGPPGPPG+PGP+GI++PGKPG QG  G PG +G PG +G 
Sbjct: 136 PPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQGE 195

Query: 179 PGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG 238
           PG PG  G KG+ G G PG PG  G  G  GP G  GP G+GK G +G+PG PG KG+ G
Sbjct: 196 PGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESG 255

Query: 239 FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF 298
            PG  GP G PG  GP G  G +G+G PGAAG PG  G  G KG PG  G  G  GP G+
Sbjct: 256 PPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGY 315

Query: 299 GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLP 358
           G PGLPG KG+RGPAG+PG  G +GE G  G PG+ G  G  G  G  G  G+PG  G P
Sbjct: 316 GMPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPP 375

Query: 359 GPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPP 418
           GPKGE GP GP G PG +G++G  G  GKPG PG+ GL G  G PG  GPKG+PG  G P
Sbjct: 376 GPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRP 435

Query: 419 GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPA 478
           G PG  G  G KG  G  G+ G RG  GIPG +GP GP G  G PG KG+PG PGPPG  
Sbjct: 436 GGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEG 495

Query: 479 GIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ--------AVMPEGFIKAGQ 530
                G  GPTGPPG PG  G +G PG PGPPGPPG PG           +P G ++ G 
Sbjct: 496 RAGEPGTAGPTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVE-GA 554

Query: 531 RPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFT 590
                G P     + ++     AFT +L+  +PA G P+ FD+ LYN    Y+P TGIFT
Sbjct: 555 VLGKGGKPQFGLGE-LSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFT 613

Query: 591 CQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQV 650
           C + G+YYF+YHVHVKGT+VWV LYKN  P  YTYDEY KGYLDQASG A++ L  NDQV
Sbjct: 614 CPVGGVYYFAYHVHVKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQV 673

Query: 651 WLQLPNAESNGLYSSEYVHSSFSGFLVAP 679
           W+Q+P+ ++NGLYS+EY+HSSFSGFL+ P
Sbjct: 674 WVQMPSDQANGLYSTEYIHSSFSGFLLCP 702



 Score =  340 bits (873), Expect = 2e-93
 Identities = 200/445 (44%), Positives = 236/445 (53%), Gaps = 57/445 (12%)

Query: 52  GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY---------------GSPGLQGEPGL 96
           GI + G+ G  G PGP G +G PGP G PG PG                G+PG  G PG 
Sbjct: 168 GITIPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGP 227

Query: 97  PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPP---GPPGIPGPAGIS 153
           PG PGP+ +GKPG+ GLPG PG+      KG+ GP G+PGPRG P   GP G PG  G+ 
Sbjct: 228 PGLPGPAGLGKPGLDGLPGAPGD------KGESGPPGVPGPRGEPGAVGPKGPPGVDGVG 281

Query: 154 VPGKPGQQGPTGAPGPRGFPGEKGAP--------GVPGMNGQKGEMG-YGAPGRPGERGL 204
           VPG  G  GP G  G +G PG +G P        G+PG+ G KG+ G  G PG  G+RG 
Sbjct: 282 VPGAAGLPGPQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGE 341

Query: 205 PGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIG 264
           PG  G  G  GP G+G  G  G+PG  G+ G RG PG  G  GP GP G PG RG +   
Sbjct: 342 PGEDGEPGEQGPQGLG--GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQ--- 396

Query: 265 KPGAAGAPGQPGIPGTKGLPGA---PGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPG 320
             G +G  G+PG+PG +GLPGA   PG  GP G PGF G+PG PG+ G  G  G  G PG
Sbjct: 397 --GPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPG 454

Query: 321 AKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380
             G +GP+G+   PGL GP G +GPQG  G+ G  GLPGP GE    G AG PG  G  G
Sbjct: 455 QPGLRGPSGI---PGLQGPAGPIGPQGLPGLKGEPGLPGPPGE----GRAGEPGTAGPTG 507

Query: 381 SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGG----PPGLPGPVGPAGAKGMPGHN 436
            PG  G PG  G PG  GP G PG PG   + G+ G      G+ G V   G K   G  
Sbjct: 508 PPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFG-L 566

Query: 437 GEAGPRGAPGIPGT-RGPIGPPGIP 460
           GE      P        P    G+P
Sbjct: 567 GELSAHATPAFTAVLTSPFPASGMP 591



 Score =  276 bits (705), Expect = 6e-74
 Identities = 166/377 (44%), Positives = 194/377 (51%), Gaps = 48/377 (12%)

Query: 35  LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEP 94
           LP    Q   P      G A  G+ G  G PG  G +G  GP G PG         +GEP
Sbjct: 215 LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGP--------RGEP 266

Query: 95  GLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISV 154
           G  GP GP  V   GVPG  G PG +GP G KG+      PG R   GPPG+ GP G  +
Sbjct: 267 GAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGE------PGTR---GPPGLIGPTGYGM 317

Query: 155 PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAP-------GRPGERGLPGP 207
           PG PG +G  G  G  G  G++G PG  G  G++G  G G P       G PG RG PGP
Sbjct: 318 PGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377

Query: 208 QGPTGPSGPPGV----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG- 262
           +G  GP GPPGV    G +G +G+ G+PG+ G+RG PG  GP GP GP+G PG  G  G 
Sbjct: 378 KGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGRPGG 437

Query: 263 ------IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGE--RGPA 313
                 +G+ G  G PGQPG+ G  G+PG  G AGP GP G  G  G PGL G    G A
Sbjct: 438 PGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRA 497

Query: 314 GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYP 373
           G PG  G  G   P G+PG PG+TGPPG  GP GP G PG+        ETG AG    P
Sbjct: 498 GEPGTAGPTG---PPGVPGSPGITGPPGPPGPPGPPGAPGAF------DETGIAG-LHLP 547

Query: 374 GAKGERGSPGSDGKPGY 390
               E    G  GKP +
Sbjct: 548 NGGVEGAVLGKGGKPQF 564


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  704 bits (1818), Expect = 0.0
 Identities = 355/648 (54%), Positives = 422/648 (65%), Gaps = 39/648 (6%)

Query: 54  AVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGL 113
           ++RGEQG  G PGP GP       GPPG PG+G PG++G+PG  G PG   VGKPG+PG+
Sbjct: 115 SLRGEQGPRGEPGPRGP------PGPPGLPGHGIPGIKGKPGPQGYPG---VGKPGMPGM 165

Query: 114 PGKPGE------RGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAP 167
           PGKPG       +G  G KG++GP G+PGP+GPPGP G+PG       GKPG  G  G P
Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI------GKPGGPGLPGQP 219

Query: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGV 227
           GP+G  G KG PG  G+ G KG+ G+G PG PG +G PG  GP GP G PGVGK G  G 
Sbjct: 220 GPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGF 279

Query: 228 PGQPGIKGDRGFPGEMGPIGP---PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284
           PG  G  G  G PGE GP GP   PG QGPPG     GIGKPG  G PGQPG PG KG  
Sbjct: 280 PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 285 GAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG 344
           G PG+ GPPG PG GKPG PG KG+RG  G+PG  G +GE+GP G PG  G  G PG  G
Sbjct: 337 GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396

Query: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404
             GP G PG+ G PGPKGE G  GP G PG KGE G  G  GKPG+ G+ G  G +G PG
Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456

Query: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464
             GPKG+ G  G PGLPG  G  G KG PG  G+ G +G PGIPG  GP GP G PG PG
Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516

Query: 465 SKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG-QAVM-- 521
            KG+PG PGPPG  GI   G+ G  GPPG PG  G  G+PGLPGPPGPPGPPG  AVM  
Sbjct: 517 PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPP 576

Query: 522 ---PEGFIKAGQRPSLSGTP---LVSANQGVTGMP---VSAFTVILSKAYPAIGTPIPFD 572
              P+G         + G        A +G  G P   + AFT  L+  +P +G P+ F+
Sbjct: 577 TPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFN 636

Query: 573 KILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGY 632
           K+LYN +Q+Y+P+TGIFTC++PG+YYF+YHVH KG +VWV L+KN  PVMYTYDEY KG+
Sbjct: 637 KLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGF 696

Query: 633 LDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM 680
           LDQASGSA++ L   D+V+LQ+P+ ++ GLY+ +YVHSSFSG+L+ PM
Sbjct: 697 LDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 744



 Score =  359 bits (921), Expect = 5e-99
 Identities = 220/461 (47%), Positives = 245/461 (53%), Gaps = 51/461 (11%)

Query: 52  GIAVRGEQGTPGPPGPAG---PRGHPGPSG---PPGKPGY---GSPGLQGEPGLPGPPGP 102
           GI   G  G PG PGP G   P+G PGP G   P G  G+   G+PG++G PG+ GPPGP
Sbjct: 206 GIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGP 265

Query: 103 SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQG 162
             VG PGV G PG  G  GP GP G  G  G PGP+GP G PG+ GP GI   GKPGQ  
Sbjct: 266 --VGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD- 321

Query: 163 PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGK 221
             G PG  GFPG KG  G+PG+ G  G  G G P      G PGP+G  G  G PG +G 
Sbjct: 322 --GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKP------GFPGPKGDRGMGGVPGALGP 373

Query: 222 RGENGVPGQPGI---KGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIP 278
           RGE G  G PGI    G+ G PG  GP+GPPG  G PG +G  GI   G  G PG  G P
Sbjct: 374 RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGI--VGPQGPPGPKGEP 431

Query: 279 GTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGE---RGPAGLPGGPGAKGEQGPAGLPGKP 334
           G +G PG PG  G  GPPG  G PG  G KGE   +G  GLPG PG  G +G  G+PG  
Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQ 491

Query: 335 GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKP 394
           GL GPPG  G  GP G  G  G+PGPKGE G  GP G+PG     G PG  G  G PGKP
Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPPGKP 547

Query: 395 GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
           G  GP+G PGLPGP G PG  GPP +  P  P          GE  P    GI G + P 
Sbjct: 548 GALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPP--------QGEYLPDMGLGIDGVKPP- 598

Query: 455 GPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPP 495
                  +   KG  G P    PA   T  L  P  P G P
Sbjct: 599 -----HAYGAKKGKNGGPAYEMPA--FTAELTAPFPPVGAP 632



 Score =  262 bits (669), Expect = 9e-70
 Identities = 171/392 (43%), Positives = 190/392 (48%), Gaps = 73/392 (18%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGP------------PGPAGPRGHPG 75
           P G+ GP          P  +   G+   G  G PGP            PGP GP G PG
Sbjct: 256 PPGMHGP----------PGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305

Query: 76  PSGPPGKPGYGSPGL---------------QGEPGLPGPPGPSAVGKPGVP------GLP 114
             GPPG PG G PG                QG PGLPGPPG   +GKPG P      G+ 
Sbjct: 306 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMG 365

Query: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG-ISVPGKPGQQGPTGAPGPRGFP 173
           G PG  GP G KG +G  G+ GP G PG PGIPGP G     G PG +G  G  GP+G P
Sbjct: 366 GVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425

Query: 174 GEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGI 233
           G KG PG+ G  G+ G +G   P  PG RGLPGP GP G +G  GV   G  GVPG  G 
Sbjct: 426 GPKGEPGLQGFPGKPGFLGEVGP--PGMRGLPGPIGPKGEAGQKGV--PGLPGVPGLLGP 481

Query: 234 KGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP--GAPGIAG 291
           KG+ G PG+ G  GPPG  G  G  GP  IG PG  G  G+PG+PG  G P  G PG+AG
Sbjct: 482 KGEPGIPGDQGLQGPPGIPGIGGPSGP--IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539

Query: 292 PPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
             GPP  GKP      G  GP G PG PG          PG PG  GPP  M P  P   
Sbjct: 540 LHGPP--GKP------GALGPQGQPGLPGP---------PGPPGPPGPPAVMPPTPP--- 579

Query: 352 PGSHGLPG-PKGETGPAGPAGYPGAKGERGSP 382
           P    LP    G  G   P  Y   KG+ G P
Sbjct: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score =  704 bits (1818), Expect = 0.0
 Identities = 355/648 (54%), Positives = 422/648 (65%), Gaps = 39/648 (6%)

Query: 54  AVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGL 113
           ++RGEQG  G PGP GP       GPPG PG+G PG++G+PG  G PG   VGKPG+PG+
Sbjct: 115 SLRGEQGPRGEPGPRGP------PGPPGLPGHGIPGIKGKPGPQGYPG---VGKPGMPGM 165

Query: 114 PGKPGE------RGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAP 167
           PGKPG       +G  G KG++GP G+PGP+GPPGP G+PG       GKPG  G  G P
Sbjct: 166 PGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGI------GKPGGPGLPGQP 219

Query: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGV 227
           GP+G  G KG PG  G+ G KG+ G+G PG PG +G PG  GP GP G PGVGK G  G 
Sbjct: 220 GPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGF 279

Query: 228 PGQPGIKGDRGFPGEMGPIGP---PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284
           PG  G  G  G PGE GP GP   PG QGPPG     GIGKPG  G PGQPG PG KG  
Sbjct: 280 PGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGI---PGIGKPGQDGIPGQPGFPGGKGEQ 336

Query: 285 GAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG 344
           G PG+ GPPG PG GKPG PG KG+RG  G+PG  G +GE+GP G PG  G  G PG  G
Sbjct: 337 GLPGLPGPPGLPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPG 396

Query: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG 404
             GP G PG+ G PGPKGE G  GP G PG KGE G  G  GKPG+ G+ G  G +G PG
Sbjct: 397 IPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456

Query: 405 LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG 464
             GPKG+ G  G PGLPG  G  G KG PG  G+ G +G PGIPG  GP GP G PG PG
Sbjct: 457 PIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPG 516

Query: 465 SKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG-QAVM-- 521
            KG+PG PGPPG  GI   G+ G  GPPG PG  G  G+PGLPGPPGPPGPPG  AVM  
Sbjct: 517 PKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPP 576

Query: 522 ---PEGFIKAGQRPSLSGTP---LVSANQGVTGMP---VSAFTVILSKAYPAIGTPIPFD 572
              P+G         + G        A +G  G P   + AFT  L+  +P +G P+ F+
Sbjct: 577 TPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFN 636

Query: 573 KILYNRQQHYDPRTGIFTCQIPGIYYFSYHVHVKGTHVWVGLYKNGTPVMYTYDEYTKGY 632
           K+LYN +Q+Y+P+TGIFTC++PG+YYF+YHVH KG +VWV L+KN  PVMYTYDEY KG+
Sbjct: 637 KLLYNGRQNYNPQTGIFTCEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGF 696

Query: 633 LDQASGSAIIDLTENDQVWLQLPNAESNGLYSSEYVHSSFSGFLVAPM 680
           LDQASGSA++ L   D+V+LQ+P+ ++ GLY+ +YVHSSFSG+L+ PM
Sbjct: 697 LDQASGSAVLLLRPGDRVFLQMPSEQAAGLYAGQYVHSSFSGYLLYPM 744



 Score =  359 bits (921), Expect = 5e-99
 Identities = 220/461 (47%), Positives = 245/461 (53%), Gaps = 51/461 (11%)

Query: 52  GIAVRGEQGTPGPPGPAG---PRGHPGPSG---PPGKPGY---GSPGLQGEPGLPGPPGP 102
           GI   G  G PG PGP G   P+G PGP G   P G  G+   G+PG++G PG+ GPPGP
Sbjct: 206 GIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGP 265

Query: 103 SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQG 162
             VG PGV G PG  G  GP GP G  G  G PGP+GP G PG+ GP GI   GKPGQ  
Sbjct: 266 --VGLPGV-GKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD- 321

Query: 163 PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGK 221
             G PG  GFPG KG  G+PG+ G  G  G G P      G PGP+G  G  G PG +G 
Sbjct: 322 --GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKP------GFPGPKGDRGMGGVPGALGP 373

Query: 222 RGENGVPGQPGI---KGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIP 278
           RGE G  G PGI    G+ G PG  GP+GPPG  G PG +G  GI   G  G PG  G P
Sbjct: 374 RGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGI--VGPQGPPGPKGEP 431

Query: 279 GTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGE---RGPAGLPGGPGAKGEQGPAGLPGKP 334
           G +G PG PG  G  GPPG  G PG  G KGE   +G  GLPG PG  G +G  G+PG  
Sbjct: 432 GLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQ 491

Query: 335 GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKP 394
           GL GPPG  G  GP G  G  G+PGPKGE G  GP G+PG     G PG  G  G PGKP
Sbjct: 492 GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGI----GKPGVAGLHGPPGKP 547

Query: 395 GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
           G  GP+G PGLPGP G PG  GPP +  P  P          GE  P    GI G + P 
Sbjct: 548 GALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPP--------QGEYLPDMGLGIDGVKPP- 598

Query: 455 GPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPP 495
                  +   KG  G P    PA   T  L  P  P G P
Sbjct: 599 -----HAYGAKKGKNGGPAYEMPA--FTAELTAPFPPVGAP 632



 Score =  262 bits (669), Expect = 9e-70
 Identities = 171/392 (43%), Positives = 190/392 (48%), Gaps = 73/392 (18%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGP------------PGPAGPRGHPG 75
           P G+ GP          P  +   G+   G  G PGP            PGP GP G PG
Sbjct: 256 PPGMHGP----------PGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPG 305

Query: 76  PSGPPGKPGYGSPGL---------------QGEPGLPGPPGPSAVGKPGVP------GLP 114
             GPPG PG G PG                QG PGLPGPPG   +GKPG P      G+ 
Sbjct: 306 VQGPPGIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGDRGMG 365

Query: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG-ISVPGKPGQQGPTGAPGPRGFP 173
           G PG  GP G KG +G  G+ GP G PG PGIPGP G     G PG +G  G  GP+G P
Sbjct: 366 GVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPP 425

Query: 174 GEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGI 233
           G KG PG+ G  G+ G +G   P  PG RGLPGP GP G +G  GV   G  GVPG  G 
Sbjct: 426 GPKGEPGLQGFPGKPGFLGEVGP--PGMRGLPGPIGPKGEAGQKGV--PGLPGVPGLLGP 481

Query: 234 KGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP--GAPGIAG 291
           KG+ G PG+ G  GPPG  G  G  GP  IG PG  G  G+PG+PG  G P  G PG+AG
Sbjct: 482 KGEPGIPGDQGLQGPPGIPGIGGPSGP--IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAG 539

Query: 292 PPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
             GPP  GKP      G  GP G PG PG          PG PG  GPP  M P  P   
Sbjct: 540 LHGPP--GKP------GALGPQGQPGLPGP---------PGPPGPPGPPAVMPPTPP--- 579

Query: 352 PGSHGLPG-PKGETGPAGPAGYPGAKGERGSP 382
           P    LP    G  G   P  Y   KG+ G P
Sbjct: 580 PQGEYLPDMGLGIDGVKPPHAYGAKKGKNGGP 611


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  463 bits (1191), Expect = e-130
 Identities = 281/652 (43%), Positives = 328/652 (50%), Gaps = 139/652 (21%)

Query: 26   QMPTGIKGPL--PNTKTQFFIPYTIKSKG-IAVRGEQGTPGPPGPAGP------------ 70
            Q PTG  GP   P    +  +P     +G    +G+ G PGPPG  GP            
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 71   RGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDV 129
            RGHPGP GPPG+ G   PGL G+ G  G PGP+ + GK G PGL G PG+RG  GP G +
Sbjct: 1014 RGHPGPPGPPGEQGL--PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGAL 1071

Query: 130  GPAGLPGPRGPPGPPGIPG---PAG----ISVPGKPGQQGPTGAPGPRGFPGEKGAPGV- 181
            G  G  GP GPPGP G PG   PAG    I +PG+PG QGP G  G +G PGEKG  G  
Sbjct: 1072 GLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1131

Query: 182  --------------------PGMNGQKGEMGY----GAPGRPGERGLPGPQGPTGPSGPP 217
                                PG +G KGE+G     G+ G  GE+G PGP GP GP G P
Sbjct: 1132 GRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQP 1191

Query: 218  GV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAG 270
            G        G RG+ G+ GQ G +G RGFPG  GP+G  G  GPPGE+G     + G  G
Sbjct: 1192 GPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKG-----ETGDVG 1246

Query: 271  APGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGA-------- 321
              G PG PG +G  GAPG  GP GPPG  G PG  G KGE G AG PG PG         
Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306

Query: 322  ----KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKG 377
                KGE GP+G  G PG  GPPG+ GP+G  G  G  G PGP GE GPAG  G PG KG
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366

Query: 378  ERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP------------KGDPGVGGPPGLPGPVG 425
            + G PG  G PG  G+PG  GP G  G PGP            KG+ G+ GPPG  GP+G
Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIG 1426

Query: 426  PAGA---------KGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGF-------------- 462
            P GA         +G+PG  GE G  G+PG  G  GP+GPPG+PG               
Sbjct: 1427 PQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPG 1486

Query: 463  ----------PGSKGDPGSPGPPGPAG----IATKGLNGPTGPPGPP------------- 495
                       G KGD G PGP G +G        G +GP GPPGPP             
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKG 1546

Query: 496  --GPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQG 545
              GP G  GE G PGPPGPPGPPG+ + P     +  R ++  + L+    G
Sbjct: 1547 SSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGNG 1598



 Score =  450 bits (1157), Expect = e-126
 Identities = 263/556 (47%), Positives = 301/556 (54%), Gaps = 64/556 (11%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPG-------PSAVGK 107
            RGE G  GP G  GP G PGP GPPG+ G  G PGL G PG  GP G       P A G+
Sbjct: 837  RGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896

Query: 108  PGVPGLPGKP---GERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG-ISVPGKPGQQGP 163
             G  G PGKP   G+RGP GP+G+ GP G+ G  GP G  G  GPAG     G  G QGP
Sbjct: 897  KGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGP 956

Query: 164  TGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPGVGKR 222
            TG PGP+G PG  G  G+PG  GQ+GE G+ G  G PG  G+ GPQGPTG +GP  +G+R
Sbjct: 957  TGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP--MGER 1014

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTK 281
            G  G PG PG +G  G  G+ G  G PGP G PG+ GP G+ G PG  G PG  G  G K
Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074

Query: 282  GLPGAPGIAGPPGPPG----------FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA--- 328
            G  G PG  GP G PG           G PG PG +G  GPAG  G PG KG QGPA   
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134

Query: 329  ------GLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSP 382
                  GLPG  G  GPPG  G +G  G PG  G  G KGE GP GP G  G  G+ G  
Sbjct: 1135 GLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPS 1194

Query: 383  GSDGKPGYPGKPGL------DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 436
            G+DG+PG  G+ GL      +GP+G PG PGP G  G+ GPPG  G  G  G  G PG  
Sbjct: 1195 GADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254

Query: 437  GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP---------GPPGPAG-IATKGLN 486
            G  GP GAPG  G +GP G  G PG  G KG+PG           GPPGP G    KG +
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGES 1314

Query: 487  GPTGPPGPPGPRGHSGE------------PGLPGPPGPPGPPGQAVMPEGFIKAGQRPSL 534
            GP+G  GPPGP+G  G+            PG PGPPG PGP GQ   P      G+ P  
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGE-PGQ 1373

Query: 535  SGTPLVSANQGVTGMP 550
            +G+P  +   G +G P
Sbjct: 1374 TGSPGPTGEPGPSGPP 1389



 Score =  449 bits (1154), Expect = e-126
 Identities = 260/566 (45%), Positives = 296/566 (52%), Gaps = 75/566 (13%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV----GK 107
            RG  G  G PG  G RG PGPSGPPG PG     G  G  G  GLPG PGP  +    G 
Sbjct: 630  RGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGP 689

Query: 108  PGVPGLPGKPGERGPYGPKGDVGPAGLPGP---RGPPGPPGIPGPAGISVPGKPGQQGPT 164
            PG PG PG  G  G  GPKG+VGP G PGP   +G PG  G+PGP G    G PG++GP 
Sbjct: 690  PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQG--AIGPPGEKGPL 747

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEM-GYGAPGRPGERGLPGPQGPTGPSGPPGV-GKR 222
            G PG  G PG  G PG PG  G  GE  G G PG  G  G PGP+G  G  G  G+ G +
Sbjct: 748  GKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTK 807

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG----IGKPGAAGAPGQPGIP 278
            GE G  G PG KGD G  G+ G IGPPGP+G  G  GP+G     G PG  G PG+ G  
Sbjct: 808  GEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867

Query: 279  GTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTG 338
            G  GLPG PG  GP G  GF  PG PG  GE+G  G PG PG +G++GP G  G+ G  G
Sbjct: 868  GVPGLPGYPGRQGPKGSIGF--PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925

Query: 339  PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK----- 393
              G  GP+G  G  G  G PG +G  GP GP G+PG KG  G PG DG PG+PG+     
Sbjct: 926  ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985

Query: 394  -PGLDGPKGNPGLPGPKGDPGVGGP---PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPG 449
              G  GP G PG+ GP+G  G  GP    G PGP GP G +G+PG  G+ G +G PG  G
Sbjct: 986  FQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAG 1045

Query: 450  TRGPIGPPGIPGFPGS------------KGDPGSPGPPGPAG-------------IATKG 484
              G  GPPG+ GFPG             KG+ G PGPPGPAG             I   G
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPG 1105

Query: 485  LNGPTGPPGPPGPRGHSGEP---------------GLPGPPGPPGPPGQAVMPEGFIKAG 529
              GP GPPGP G +G  GE                GLPGP GP GPPG+        + G
Sbjct: 1106 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPG 1165

Query: 530  QRPSL-----SGTPLVSANQGVTGMP 550
            Q+ S       G P  +  QG  G P
Sbjct: 1166 QKGSKGDKGEQGPPGPTGPQGPIGQP 1191



 Score =  428 bits (1101), Expect = e-120
 Identities = 261/570 (45%), Positives = 286/570 (50%), Gaps = 104/570 (18%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPG-PSAVGKPGV 110
            +  RG  G PGP G  GP+G PGP GPPG  G  G PG +G  G  G PG P   G PG 
Sbjct: 669  VGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728

Query: 111  PGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG----PAGISVPGKPGQQGPTGA 166
             GLPG  G  GP G KG +G  GLPG  G  GPPG PG    P      G PG QGP G 
Sbjct: 729  QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGY 788

Query: 167  PGPRGFPGEKGAPGVPGMNGQKGEMGY-------GAPGRPGERGLPGPQGPTGPSGPPG- 218
            PGPRG  G  G  G+ G  G+KGE G+       G  G  GE G PGP+G  GP GP G 
Sbjct: 789  PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGR 848

Query: 219  ------------VGKRGENGVPGQPGI---------------------KGDRGFPGEMGP 245
                         G++G+ GVPG PG                      KG RG PG+ GP
Sbjct: 849  GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908

Query: 246  IGPPGPQGPPGERGPEGI-GKP---------GAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295
             G  GP GP GERGP GI GKP         G AG PG+ G  G +G  G PG  GPPGP
Sbjct: 909  RGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP 968

Query: 296  PG-FGKPGLPGLKGE---RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
            PG  G PG PG +GE   +G  G PG PG  G QGP G  G  G  G PG  GP G +G+
Sbjct: 969  PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028

Query: 352  PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD 411
            PG  G  G KG+ GPAG  G  G  G RG PG  G PG  G  GL G +G PG PGP G 
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 412  PGVGGP------------PGLPGPVGPAGAKGMPGHNGEAGP------RGAPGIPGTRGP 453
            PG  GP            PG  GP GPAG KG PG  G  GP      +G  G+PG  GP
Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 454  IGPP---------GIPGFPGSKGDPGSPGPPGPAG-IATKGLNGPTGPPGPPGPRGH--- 500
            +GPP         G PG  GSKGD G  GPPGP G     G  GP+G  G PGPRG    
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208

Query: 501  ------SGEPGLPGPPGP------PGPPGQ 518
                   G  G PGPPGP      PGPPG+
Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238



 Score =  417 bits (1073), Expect = e-116
 Identities = 252/572 (44%), Positives = 294/572 (51%), Gaps = 62/572 (10%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY---- 85
            GI GP    K Q   P  I+  G+ + G  G  GP G  GP G  GP+G  G PG     
Sbjct: 444  GIGGPR-GEKGQKGEPAIIEP-GMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPP 501

Query: 86   GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPY--------------------GP 125
            G PGL G  GLPGPPG + +  P   G  G  G +GP                     GP
Sbjct: 502  GRPGLPGADGLPGPPG-TMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGP 560

Query: 126  KGDVGPAGLPGPRGPPGPPGIPGPAGISVP----GKPGQQGPTGAPGPRGFPGEKGAPGV 181
             G +G  G PGP GPPG  G+ G  G   P    G  G  GP G PG RG  G  GA G+
Sbjct: 561  AGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGM 620

Query: 182  PGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPG-VGKRGENGVPGQPGIKGDRGF 239
            PG  G KG+ G+ G  G PGE+G  G  GP+GP GPPG  G+RG++G  G  G+ G+ G 
Sbjct: 621  PGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP 680

Query: 240  PGEMGPIGPPGPQGPPGERGPEG-------IGKPGAAGAPGQPGIPGTKGLPGAPGIAGP 292
             G +GP GPPGP GPPG  G +G       +G  G  G PGQ G PG +GLPG  G  GP
Sbjct: 681  RGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740

Query: 293  PGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
            PG  G  GKPGLPG+ G  GP G PG  G  GE+G  G P      GP G +G  GP+G+
Sbjct: 741  PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPP------GPQGPIGYPGPRGV 794

Query: 352  PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD 411
             G+ G+ G KG  G  G  G+PG KG+ G  G  G+ G PG  G DGP+G  G  GP GD
Sbjct: 795  KGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854

Query: 412  PGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS 471
            PG  GPPG  G +G  G  G PG  G  G  G PG PG  G  G  G PG PG +G  G 
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 472  PGP---PGPAGIATK-------GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVM 521
             GP    GP GI  K       G +GP GPPG  GP G  G  G PGP GPPGPPG+  +
Sbjct: 915  TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGL 974

Query: 522  PEGFIKAGQ-----RPSLSGTPLVSANQGVTG 548
            P    + G+     +    G P V   QG TG
Sbjct: 975  PGHPGQRGETGFQGKTGPPGPPGVVGPQGPTG 1006



 Score =  279 bits (713), Expect = 7e-75
 Identities = 189/492 (38%), Positives = 222/492 (45%), Gaps = 103/492 (20%)

Query: 141 PGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGM---------------- 184
           P  P  PG AG  +P        +  P P   PGE GA  + G                 
Sbjct: 364 PDQPTDPG-AGAEIPTSTADTSNSSNPAPP--PGE-GADDLEGEFTEETIRNLDENYYDP 419

Query: 185 ----NGQKGEMGYGAPGRPGE--RGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG 238
                    E+G G P        G+ GP+G  G  G P + + G   + G PG +G  G
Sbjct: 420 YYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGML-IEGPPGPEGPAG 478

Query: 239 FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGT------------------ 280
            PG  G +GP G  G PGERGP G  +PG  GA G PG PGT                  
Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPG--RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKG 536

Query: 281 ---------------------KGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGP 319
                                +G  G  G+ G PGP   G PG  GLKGE G  G  G  
Sbjct: 537 PMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGP--VGPPGSGGLKGEPGDVGPQGPR 594

Query: 320 GAKGEQGPAGLPGKPGLTGP------PGNMGPQGPKGIPGSHGLPGPK---GETGPAGPA 370
           G +G  GPAG PG+ G  G       PG  GP+G +G  G  GLPG K   G+ GP+GP 
Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPP 654

Query: 371 GYPGAKGERGSPGSDGKPGYPGKP---GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPA 427
           G PG  GERG  G  G  G PG+P   GL GPKG PG PGP G  G+ G PG  G VGP 
Sbjct: 655 GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQ 714

Query: 428 GAKGMPGHNGE------AGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA 481
           G  G PG  G        GP+GA G PG +GP+G PG+PG PG+ G PG PG  GP G  
Sbjct: 715 GEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPG-- 772

Query: 482 TKGLNGPTGPPGP---PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTP 538
            KG  GP GP GP   PGPRG  G  G+ G  G  G  G+    +GF      P   G  
Sbjct: 773 EKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE----DGF------PGFKGDM 822

Query: 539 LVSANQGVTGMP 550
            +  ++G  G P
Sbjct: 823 GIKGDRGEIGPP 834


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  461 bits (1187), Expect = e-130
 Identities = 278/586 (47%), Positives = 308/586 (52%), Gaps = 129/586 (22%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGL---------QGEPGLPGPPGP 102
            +GE G  GPPGP GP G PG SG PG  G     G PGL         +GEPGLPGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 103  ---------SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGL------PGPRGPPGPPGIP 147
                        G+PG+PG+PG  G +G  G  GD G  GL      PGP GP G PG+P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 148  GPAGISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPG 197
            G  G+  P          G PG QG  G PGP G PG+ G+PG+PG  G KG+ G  + G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 198  RPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250
             PG   LPGP+G  G  G PG       VG  G  G+PG PG KG  G PG  G  GPPG
Sbjct: 1075 LPG---LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 251  PQG---PPGERG-PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP------PGPPGFGK 300
            P+G   PPG  G P   G  G  G PGQPG PG KG PG  GI GP      PG PGFG 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 301  PG---LPGLKGERGPAGLPGGPG------AKGE---------QGPAGLPGKPG--LTGPP 340
            PG   LPGL G++G  GLPG PG       KGE         QGP G PG PG  L GP 
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 341  GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG------KP 394
            GN GPQGP G PG  GLPGP+G   P G  G  G KGE+G+PG  G PG PG       P
Sbjct: 1252 GNPGPQGPPGRPGFQGLPGPEG---PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1308

Query: 395  GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG---PRGAPGIPGT- 450
            GL G  G PGL G KGDPG+ G PG PG  GP+G  G  G  GE G   P G PG+PG  
Sbjct: 1309 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1368

Query: 451  ------RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG----- 499
                  +G  GPPGIPG PG KG PG  GP        +GL GPTGPPG PG  G     
Sbjct: 1369 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGPTGPPGDPGRNGLPGFD 1420

Query: 500  ----HSGEPGLPGPPG---------------PPGPPGQAVMPEGFI 526
                  G+PGLPG PG               PPGPPG + +  GF+
Sbjct: 1421 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFL 1466



 Score =  460 bits (1183), Expect = e-129
 Identities = 279/612 (45%), Positives = 321/612 (52%), Gaps = 100/612 (16%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKGIAVR-GEQGTPGPPGPAGPRGHPG-----PSGPPGKP 83
            G+ GP P  K    IP    + G   R G +G PGPPG  GP+G PG     P GPPG P
Sbjct: 707  GLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 84   GY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPG--PRGP 140
            G+ G+ G +G+ G PGPPGP   G+ G+ GLPG  G+ GP G  G +GP GLPG   +GP
Sbjct: 766  GFKGALGPKGDRGFPGPPGPP--GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 141  PGPPGIPGPAGI----SVPGKPGQQGPTG--APGPRGFPGEKGAPGVPGMNGQKGEMGY- 193
            PGPPGIPGP G      +PG+ G  GP G   PGP   PGE+G+PG+PG  G  G  G  
Sbjct: 824  PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP---PGERGSPGIPGAPGPIGPPGSP 880

Query: 194  ---------GAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKG---DR 237
                     G PG  GE G+ GP GP GP G PG     G +G++G+ GQPG+ G   ++
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 238  GFPGEMGPIGPPGPQGP-----PGERGPEGI-------GKPGAAGAPGQPGIPGTKGLPG 285
            G  GE G  GPPGP  P      GE+G  G+       G  G  G PG PG PG  G PG
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 286  APGIAGPPGPPGF-GKPGL---PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
             PG  GP G PG  G+PGL   PGLKG  G  G PG  G +G  GP+G+PG+PG  G PG
Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 342  NMGPQGPKGIP--GSHGLPGPKGETG----PAGPA--------------GYPGAKGERGS 381
              G +G  GI   G  GLPGPKGE G    P  P               G PGAKG+ G 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 382  PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP 441
            PG  G PG PG  G+ GP GNPGLPG  G  G GG PG PGP G  G  G  G  G AG 
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180

Query: 442  RGAPGIPGTRGPIGPPGIPGFPGSKGD------------------------PGSPGPPGP 477
            +G PG PG   P GPPG+PG  G KGD                        PG  GPPGP
Sbjct: 1181 KGEPGQPGFGNP-GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239

Query: 478  AGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGT 537
             G     L GP G PGP GP G  G  GLPGP GPPG PG   +       GQ P L G 
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQ-PGLPGL 1298

Query: 538  PLVSANQGVTGM 549
            P +  +QG  G+
Sbjct: 1299 PGLKGDQGPPGL 1310



 Score =  454 bits (1168), Expect = e-127
 Identities = 270/616 (43%), Positives = 306/616 (49%), Gaps = 126/616 (20%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG-PSAVGKPGVPGLPG 115
            G  G PGP G  GP G PGP GPPG PG G  G  G PG+PGP G P   G PG  G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 116  KPG--ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS----VPGKPGQQGPTGAPGP 169
             PG    GP G +G  G  G PGP GPPG PG+PG AG S      G+ G  GP G PGP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 170  RGFPGEKGAPGVPGMNGQKGEMGYGAP----GRPGERGLPGPQGPTGPSGPPGVGKRGEN 225
             G PG  G PG+ G +G +G+ G   P    G  GE GLPGP GP  P+     G++GE 
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 226  GVPGQPGIKGDRGF------PGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIP 278
            G+PG PG+ G +G+      PG+ G  G PG  GPPG +G  G+ G+PG  G PG  G  
Sbjct: 970  GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTI 1029

Query: 279  GTKGLPGAPGIAGPPGPPG------------------------FGKPGLPGLKGERGPAG 314
            G  G PG  G+ GPPGP G                         G PGLPG KGE G  G
Sbjct: 1030 GDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089

Query: 315  LPGGPGAKGEQGPAGLPG---------KPGLTGPPGNMGPQGPKGI---PGSHGLPGPKG 362
             PG PG KG  G  GLPG         +PGL G PG  GP GPKGI   PG+ GLPG  G
Sbjct: 1090 YPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 363  ETGPAGPAGYPGAKGERGSPGSDG-----------------KPGYPGKPGLDGPKG---- 401
              G  G  G PG  GE+G PG DG                  PG PG PGL G KG    
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 402  -----NPGLPGPKGDPGVGG---------PPGLPGPV--------GPAGAKGMPGHNGEA 439
                 NPGLPGPKG+PG  G         PPG PGP         GP G  G PG  G  
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269

Query: 440  GPRGAPGIPGT------RGPIGPPGIPGFPGSKGDPGSPG---------------PPGPA 478
            GP G PG+PG       +G  G PG+PG PG KGD G PG                PG  
Sbjct: 1270 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1329

Query: 479  GI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQ-----RP 532
            G+    G+ GP+G PG  GP G  G  G PGPPG PGP GQ+++ +G   AG      +P
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG--DAGPPGIPGQP 1387

Query: 533  SLSGTPLVSANQGVTG 548
             L G P     QG+ G
Sbjct: 1388 GLKGLPGPQGPQGLPG 1403



 Score =  446 bits (1146), Expect = e-125
 Identities = 267/592 (45%), Positives = 299/592 (50%), Gaps = 84/592 (14%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKG----IAVRGEQGTPGPPGPAGPRGHPGPSGPPG--KP 83
            G+ G LP T  Q  +P     KG    I  +GE+G PG PG  G  G+ GP GPPG   P
Sbjct: 570  GLPG-LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 84   G----YGSPGLQGEPGLPGPPGPSA-----VGKPGVPGLPGKPGERGPYGPKGDVGPAGL 134
            G     G  G+ G PG PG PGP       + +PG PGLPG PG  G  G  GD G  G 
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 135  PGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE------KGAPGVPGMNGQK 188
            PG  G PG  G PG  GI +PG PG +G  G PGP G PG       +G PG PG  G K
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 189  GEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP 248
            GE G+  PG PG  GLPG +G  GP        +G+ G PG PG  G  G  G  GP G 
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGP--------KGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 249  PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP---GAPGIAGPPGPPGFGKPGLPG 305
             GP G PG  GP G+   G  G PG PGIPG  G P   G PG  G PGPPG   PG P 
Sbjct: 801  VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP- 859

Query: 306  LKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNM---------GPQGPKGIPGSHG 356
              GERG  G+PG PG  G  G  GLPGK G +G PG           GP GP GIPG  G
Sbjct: 860  --GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 357  LPGPKGETGPAGPAGYPGAKGER--------------------GSPGSDGKPGYPGKPGL 396
            +PG KG+ G  G  G PG  GE+                    GS G  G+PG PG PG+
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGV 977

Query: 397  DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP---------RGAPGI 447
             GPKG  GLPG  G PG+ G PGLPGP GP G  G+PG  G  GP          G PG 
Sbjct: 978  SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 448  PGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGP---------PGPPGPR 498
             G  GP GP G+PG PGS G PG  G  G  GI++ GL G  GP         PG PG +
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G  G+PGLPG PG PG  GQ  +P GF      P   G      N G+ G P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLP-GFPGTPGPPGPKGISGPPGNPGLPGEP 1148



 Score =  423 bits (1088), Expect = e-118
 Identities = 288/726 (39%), Positives = 327/726 (45%), Gaps = 221/726 (30%)

Query: 28  PTGIKGP--LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85
           P GI+GP  LP        P T    G+   G  G PGP G  G  G  G  G PG PG+
Sbjct: 88  PKGIRGPPGLPG------FPGTPGLPGMP--GHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 86  GSPGLQGEPGLPGPPG-------------PSAVGKPGVPGLPGKPGERGPYGPKGDVGPA 132
             PGLQG PG PG PG             P   G PG PG PG  G  GP G  G +GP 
Sbjct: 140 --PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP 197

Query: 133 GLPGPRGPPGPPGIPGPAG------ISVPGKPGQQGPTGAPGP----------------- 169
           G PG  GPPGPPG+PGP G          G+ G+QG  G PGP                 
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 170 --RGFPGEKGAPGVPGM----------NGQKGEMGY------------------------ 193
             +G PG++G PG PG+           G+KGE G                         
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 194 -GAPGRPGERGLPGPQGPTGPSGPPG-----------VGKRGENGVPGQPGIKGDRGFPG 241
            G PG PG  G  G +G TGP GPPG           +G++G  G+PG PG KG+RGFPG
Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 242 EMGP-----------IGPPGPQGPPGERGPEGIGKPGAAGAPGQPGI---PGTKGLPGAP 287
             GP           +GPPGP G PGERG +G   P     PG PG+   PG  GLPG P
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 288 GIAGP----------PGPPGFGKPGLPGLKGERGPAGLPGGPG-------AKGEQGPAGL 330
           G AGP          PGPP  G PG PG KG +G  G+ G  G         G  GP G 
Sbjct: 438 GPAGPHIPPSDEICEPGPP--GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 331 PGKPGLTGPPGNM------------GPQGPKGIPGSHGLPGPKGETGPAGPAG----YPG 374
           PG PGL GPPG++            G  GPKG+PG  G PG  G  G  G  G    +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP------GVGGPPGLP------- 421
            KG++G  GS G PG PG PG  G  G PGLPGPKG+P      G  GPPG P       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 422 ----------GPVGPAGAKGM------PGHNGEAGPRGAP-------------------- 445
                     GP GP G KG+      PG  G  GP+G P                    
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 446 --GIPGTRGPIGPPGIPGFPGSKGDP-----GSPGPPGPAGI----------ATKGLNGP 488
             G+PG  G  G PG+PG PGSKG+P     G PGPPGP G            T G  G 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 489 TGPPGPPGPRGHSGEPG--LPGPPGPPGPPG--QAVMPEGFIKAGQRPSLSGTPLVSANQ 544
            GPPGPPG  G  GEPG  LPGPPGPPG PG   A+ P+G           G P      
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPGPPGRT 789

Query: 545 GVTGMP 550
           G+ G+P
Sbjct: 790 GLDGLP 795



 Score =  389 bits (998), Expect = e-108
 Identities = 266/652 (40%), Positives = 299/652 (45%), Gaps = 200/652 (30%)

Query: 89  GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
           G++GE G  G PG    G PG+PG PG  G  GP G KGD G  G PGP+G  GPPG+PG
Sbjct: 42  GIKGEKGERGFPGLE--GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPG 99

Query: 149 PAGISVPGKPGQQGPTGAPGPR------------------GFPGEKGAPGVPGMNGQKGE 190
             G   PG PG  G  GAPGP+                  GFPG +G PG PG+ G KGE
Sbjct: 100 FPG--TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 191 MGY-------------GAPGRPGERGLPGP---QGPTGPSGPPGV--------------- 219
            G              G PG PG +GLPGP    GP GP GPPG+               
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 220 ---------GKRGENGVPGQPG----------------IKGDRGFPGEMGPIGPPGPQGP 254
                    G++GE G+ G PG                 KGD+G PG+ GP GPPG +GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 255 P-------GERGPEG----IGKPGAAGAPGQPGIPGTKGLPGAP------------GIAG 291
           P       GE+G +G     GKPG  G  GQPGIPG  G PG P            G  G
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 292 PPGPPG-----------------FGKPGLPGLKGER------GPAGLPGGPGA--KGEQG 326
           PPGPPG                  G PGLPG KGER      GP GLPG PGA   G  G
Sbjct: 338 PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 327 PAGLPGKPGL---TGPPGNM--GPQGPKGIPGSHGLPGPKG-------------ETGPAG 368
           P G PG+ G     GPPG    GP G  G PG+ GLPGP G             E GP G
Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 369 PAGYPGAKGERG----------------SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD- 411
           P G PG KG +G                  G  G PG PG PGL GP G+ G PG KG+ 
Sbjct: 458 PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 412 --PGVGGPPGLPGPVGPAGAKGMP----------------GHNGEAGPRGAPGIPGTRGP 453
              G  GP GLPG  G  GA G P                G  GE G  GAPG+PG  G 
Sbjct: 518 GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 454 IGPPGIPGFPGSKGDP------GSPGPPGPAGI-ATKGLNGPTGPP--GPPGP------R 498
            G  G+PG PG KG+P      G  GPPG  G+    G  GP GPP  GPPGP      +
Sbjct: 578 PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G +G PG PG PGP G PGQ +   G      +P L G P    + G+ G P
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPG------KPGLPGNPGRDGDVGLPGDP 683



 Score =  360 bits (923), Expect = 3e-99
 Identities = 205/424 (48%), Positives = 238/424 (56%), Gaps = 57/424 (13%)

Query: 55   VRGEQGTPGPPGPAGPRGHPG-----------PSGPPGKPGY-GSPGLQG---EPGLPGP 99
            V G+ G+PG PG  G +G PG           P G PG PGY G+PG++G   +PGLPG 
Sbjct: 1049 VPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGL 1108

Query: 100  PG-PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP------PGIPGPAGI 152
            PG P A G+PG+PG PG PG   P GPKG  GP G PG  G PGP      PG PGP G 
Sbjct: 1109 PGTPGAKGQPGLPGFPGTPG---PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGE 1165

Query: 153  SVPGKPGQQGPTGAPGPRGFPGEKG-----APGVPGMNGQKGEMGYGAPGRPGERGLPGP 207
               GKPGQ G  G  G +G PG+ G      PG+PG++GQKG+ G   PG PG  GLPGP
Sbjct: 1166 K--GKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL--PGIPGNPGLPGP 1221

Query: 208  QGPTGPSGPPGVGKRGENGVPGQPG--IKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGK 265
            +G  G  G PGV  +G  G PG PG  ++G +G PG  GP G PG QG PG  GP G+  
Sbjct: 1222 KGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGL-- 1277

Query: 266  PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGE 324
            PG  G  G+ G PG  GLPG PG+ G  GPPG  G PG PGL G +G  GLPG PG  G 
Sbjct: 1278 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1337

Query: 325  QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL----------------PGPKGETGPAG 368
            +GP+G+PG  G  G PG +GP GP G+PG  G                 PG KG  GP G
Sbjct: 1338 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1397

Query: 369  PAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAG 428
            P G PG  G  G PG +G PG+ G  G  G  G PG PG +G  G  GP GL GP GP G
Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457

Query: 429  AKGM 432
               +
Sbjct: 1458 TSSV 1461



 Score =  214 bits (546), Expect = 2e-55
 Identities = 137/328 (41%), Positives = 160/328 (48%), Gaps = 65/328 (19%)

Query: 264 GKPGAAGA-----PGQP----GIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314
           G+P  A A     PG      GI G KG  G PG+ G         PGLPG  G  GP  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG--------HPGLPGFPGPEGP-- 70

Query: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374
               PG +G++G  G+PG PG   P G  GP G  G PG+ GLPG  G  G  GP G PG
Sbjct: 71  ----PGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG------VGGPPGLPGPVGPAG 428
             G +G  G  G PG+PG   L GP G PG+PG KG+PG      + GP G PG  GP G
Sbjct: 124 CNGTKGERGFPGSPGFPG---LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 429 AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGS-----------KGDPGSPGPPGP 477
            +G+PG  G  GP G PG PG  GP GPPG+PG  G+           KG+ G  GPPGP
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 478 AGIAT--------------KGLNGPTGPPGPPGPRGHSGEP-GLPGPPGPPGPPGQAVMP 522
            G  +              +GL G  GPPGPPG RG  G P G  G  G  G PG+   P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 523 EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
               + GQ P + G P    + G  G P
Sbjct: 301 GKDGENGQ-PGIPGLP---GDPGYPGEP 324


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  461 bits (1186), Expect = e-129
 Identities = 275/580 (47%), Positives = 306/580 (52%), Gaps = 120/580 (20%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGL---------QGEPGLPGPPGP 102
            +GE G  GPPGP GP G PG SG PG  G     G PGL         +GEPGLPGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 103  ---------SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGL------PGPRGPPGPPGIP 147
                        G+PG+PG+PG  G +G  G  GD G  GL      PGP GP G PG+P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 148  GPAGISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPG 197
            G  G+  P          G PG QG  G PGP G PG+ G+PG+PG  G KG+ G  + G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 198  RPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250
             PG   LPGP+G  G  G PG       VG  G  G+PG PG KG  G PG  G  GPPG
Sbjct: 1075 LPG---LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 251  PQG---PPGERG-PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP------PGPPGFGK 300
            P+G   PPG  G P   G  G  G PGQPG PG KG PG  GI GP      PG PGFG 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 301  PG---LPGLKGERGPAGLPGGPG------AKGEQGPAGLPGKPGLTGPPGNMGP--QGPK 349
            PG   LPGL G++G  GLPG PG       KGE G  G PG  G  GPPG+ GP  +GPK
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 350  GIPGSHGLPGPKGETGPAGPAGYPG---AKGERGSPGSDGKPGYPG------KPGLDGPK 400
            G PG  G PG  G  GP GP G PG    KGE+G+PG  G PG PG       PGL G  
Sbjct: 1252 GNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNP 1311

Query: 401  GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG---PRGAPGIPGT------- 450
            G PGL G KGDPG+ G PG PG  GP+G  G  G  GE G   P G PG+PG        
Sbjct: 1312 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1371

Query: 451  RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG---------HS 501
            +G  GPPGIPG PG KG PG  GP        +GL GPTGPPG PG  G           
Sbjct: 1372 KGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGPTGPPGDPGRNGLPGFDGAGGRK 1423

Query: 502  GEPGLPGPPG---------------PPGPPGQAVMPEGFI 526
            G+PGLPG PG               PPGPPG + +  GF+
Sbjct: 1424 GDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFL 1463



 Score =  458 bits (1178), Expect = e-129
 Identities = 267/613 (43%), Positives = 307/613 (50%), Gaps = 123/613 (20%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG-PSAVGKPGVPGLPG 115
            G  G PGP G  GP G PGP GPPG PG G  G  G PG+PGP G P   G PG  G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 116  KPG--ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS----VPGKPGQQGPTGAPGP 169
             PG    GP G +G  G  G PGP GPPG PG+PG AG S      G+ G  GP G PGP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 170  RGFPGEKGAPGVPGMNGQKGEMGYGAP----GRPGERGLPGPQGPTGPSGPPGVGKRGEN 225
             G PG  G PG+ G +G +G+ G   P    G  GE GLPGP GP  P+     G++GE 
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 226  GVPGQPGIKGDRGF------PGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIP 278
            G+PG PG+ G +G+      PG+ G  G PG  GPPG +G  G+ G+PG  G PG  G  
Sbjct: 970  GLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTI 1029

Query: 279  GTKGLPGAPGIAGPPGPPG------------------------FGKPGLPGLKGERGPAG 314
            G  G PG  G+ GPPGP G                         G PGLPG KGE G  G
Sbjct: 1030 GDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPG 1089

Query: 315  LPGGPGAKGEQGPAGLPG---------KPGLTGPPGNMGPQGPKGI---PGSHGLPGPKG 362
             PG PG KG  G  GLPG         +PGL G PG  GP GPKGI   PG+ GLPG  G
Sbjct: 1090 YPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPG 1149

Query: 363  ETGPAGPAGYPGAKGERGSPGSDG-----------------KPGYPGKPGLDGPKG---- 401
              G  G  G PG  GE+G PG DG                  PG PG PGL G KG    
Sbjct: 1150 PVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGL 1209

Query: 402  -----NPGLPGPKGDPGVGGPPGLPGPVGPAGAKG--MPGHNGEAGPRGAPGIPGTRGPI 454
                 NPGLPGPKG+PG  G PG+ GP GP G+ G  + G  G  GP+G PG PG  GP 
Sbjct: 1210 PGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPE 1269

Query: 455  GPPGIPGFPGSKGDPGSPGPPGPAGI---------------------------------- 480
            GPPG+PG  G KG+ G+PG PG  G+                                  
Sbjct: 1270 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1329

Query: 481  ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQ-----RPSLS 535
               G+ GP+G PG  GP G  G  G PGPPG PGP GQ+++ +G   AG      +P L 
Sbjct: 1330 GFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG--DAGPPGIPGQPGLK 1387

Query: 536  GTPLVSANQGVTG 548
            G P     QG+ G
Sbjct: 1388 GLPGPQGPQGLPG 1400



 Score =  446 bits (1146), Expect = e-125
 Identities = 267/592 (45%), Positives = 299/592 (50%), Gaps = 84/592 (14%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKG----IAVRGEQGTPGPPGPAGPRGHPGPSGPPG--KP 83
            G+ G LP T  Q  +P     KG    I  +GE+G PG PG  G  G+ GP GPPG   P
Sbjct: 570  GLPG-LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 84   G----YGSPGLQGEPGLPGPPGPSA-----VGKPGVPGLPGKPGERGPYGPKGDVGPAGL 134
            G     G  G+ G PG PG PGP       + +PG PGLPG PG  G  G  GD G  G 
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 135  PGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE------KGAPGVPGMNGQK 188
            PG  G PG  G PG  GI +PG PG +G  G PGP G PG       +G PG PG  G K
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 189  GEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP 248
            GE G+  PG PG  GLPG +G  GP        +G+ G PG PG  G  G  G  GP G 
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGP--------KGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 249  PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP---GAPGIAGPPGPPGFGKPGLPG 305
             GP G PG  GP G+   G  G PG PGIPG  G P   G PG  G PGPPG   PG P 
Sbjct: 801  VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP- 859

Query: 306  LKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNM---------GPQGPKGIPGSHG 356
              GERG  G+PG PG  G  G  GLPGK G +G PG           GP GP GIPG  G
Sbjct: 860  --GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 357  LPGPKGETGPAGPAGYPGAKGER--------------------GSPGSDGKPGYPGKPGL 396
            +PG KG+ G  G  G PG  GE+                    GS G  G+PG PG PG+
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGV 977

Query: 397  DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP---------RGAPGI 447
             GPKG  GLPG  G PG+ G PGLPGP GP G  G+PG  G  GP          G PG 
Sbjct: 978  SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 448  PGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGP---------PGPPGPR 498
             G  GP GP G+PG PGS G PG  G  G  GI++ GL G  GP         PG PG +
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G  G+PGLPG PG PG  GQ  +P GF      P   G      N G+ G P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLP-GFPGTPGPPGPKGISGPPGNPGLPGEP 1148



 Score =  423 bits (1088), Expect = e-118
 Identities = 288/726 (39%), Positives = 327/726 (45%), Gaps = 221/726 (30%)

Query: 28  PTGIKGP--LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85
           P GI+GP  LP        P T    G+   G  G PGP G  G  G  G  G PG PG+
Sbjct: 88  PKGIRGPPGLPG------FPGTPGLPGMP--GHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 86  GSPGLQGEPGLPGPPG-------------PSAVGKPGVPGLPGKPGERGPYGPKGDVGPA 132
             PGLQG PG PG PG             P   G PG PG PG  G  GP G  G +GP 
Sbjct: 140 --PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP 197

Query: 133 GLPGPRGPPGPPGIPGPAG------ISVPGKPGQQGPTGAPGP----------------- 169
           G PG  GPPGPPG+PGP G          G+ G+QG  G PGP                 
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 170 --RGFPGEKGAPGVPGM----------NGQKGEMGY------------------------ 193
             +G PG++G PG PG+           G+KGE G                         
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 194 -GAPGRPGERGLPGPQGPTGPSGPPG-----------VGKRGENGVPGQPGIKGDRGFPG 241
            G PG PG  G  G +G TGP GPPG           +G++G  G+PG PG KG+RGFPG
Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 242 EMGP-----------IGPPGPQGPPGERGPEGIGKPGAAGAPGQPGI---PGTKGLPGAP 287
             GP           +GPPGP G PGERG +G   P     PG PG+   PG  GLPG P
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 288 GIAGP----------PGPPGFGKPGLPGLKGERGPAGLPGGPG-------AKGEQGPAGL 330
           G AGP          PGPP  G PG PG KG +G  G+ G  G         G  GP G 
Sbjct: 438 GPAGPHIPPSDEICEPGPP--GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 331 PGKPGLTGPPGNM------------GPQGPKGIPGSHGLPGPKGETGPAGPAG----YPG 374
           PG PGL GPPG++            G  GPKG+PG  G PG  G  G  G  G    +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP------GVGGPPGLP------- 421
            KG++G  GS G PG PG PG  G  G PGLPGPKG+P      G  GPPG P       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 422 ----------GPVGPAGAKGM------PGHNGEAGPRGAP-------------------- 445
                     GP GP G KG+      PG  G  GP+G P                    
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 446 --GIPGTRGPIGPPGIPGFPGSKGDP-----GSPGPPGPAGI----------ATKGLNGP 488
             G+PG  G  G PG+PG PGSKG+P     G PGPPGP G            T G  G 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 489 TGPPGPPGPRGHSGEPG--LPGPPGPPGPPG--QAVMPEGFIKAGQRPSLSGTPLVSANQ 544
            GPPGPPG  G  GEPG  LPGPPGPPG PG   A+ P+G           G P      
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPGPPGRT 789

Query: 545 GVTGMP 550
           G+ G+P
Sbjct: 790 GLDGLP 795



 Score =  389 bits (998), Expect = e-108
 Identities = 266/652 (40%), Positives = 299/652 (45%), Gaps = 200/652 (30%)

Query: 89  GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
           G++GE G  G PG    G PG+PG PG  G  GP G KGD G  G PGP+G  GPPG+PG
Sbjct: 42  GIKGEKGERGFPGLE--GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPG 99

Query: 149 PAGISVPGKPGQQGPTGAPGPR------------------GFPGEKGAPGVPGMNGQKGE 190
             G   PG PG  G  GAPGP+                  GFPG +G PG PG+ G KGE
Sbjct: 100 FPG--TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 191 MGY-------------GAPGRPGERGLPGP---QGPTGPSGPPGV--------------- 219
            G              G PG PG +GLPGP    GP GP GPPG+               
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 220 ---------GKRGENGVPGQPG----------------IKGDRGFPGEMGPIGPPGPQGP 254
                    G++GE G+ G PG                 KGD+G PG+ GP GPPG +GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 255 P-------GERGPEG----IGKPGAAGAPGQPGIPGTKGLPGAP------------GIAG 291
           P       GE+G +G     GKPG  G  GQPGIPG  G PG P            G  G
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 292 PPGPPG-----------------FGKPGLPGLKGER------GPAGLPGGPGA--KGEQG 326
           PPGPPG                  G PGLPG KGER      GP GLPG PGA   G  G
Sbjct: 338 PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 327 PAGLPGKPGL---TGPPGNM--GPQGPKGIPGSHGLPGPKG-------------ETGPAG 368
           P G PG+ G     GPPG    GP G  G PG+ GLPGP G             E GP G
Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 369 PAGYPGAKGERG----------------SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD- 411
           P G PG KG +G                  G  G PG PG PGL GP G+ G PG KG+ 
Sbjct: 458 PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 412 --PGVGGPPGLPGPVGPAGAKGMP----------------GHNGEAGPRGAPGIPGTRGP 453
              G  GP GLPG  G  GA G P                G  GE G  GAPG+PG  G 
Sbjct: 518 GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 454 IGPPGIPGFPGSKGDP------GSPGPPGPAGI-ATKGLNGPTGPP--GPPGP------R 498
            G  G+PG PG KG+P      G  GPPG  G+    G  GP GPP  GPPGP      +
Sbjct: 578 PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G +G PG PG PGP G PGQ +   G      +P L G P    + G+ G P
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPG------KPGLPGNPGRDGDVGLPGDP 683



 Score =  233 bits (594), Expect = 4e-61
 Identities = 136/286 (47%), Positives = 155/286 (54%), Gaps = 29/286 (10%)

Query: 44   IPYTIKSKGIAVRGEQGTPGPPGPAGPR------------GHPGPSGPPGKPGY-GSPGL 90
            IP     KG   +   G PGPPG  G              G+PG  GP G+PG+ G PG+
Sbjct: 1174 IPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGV 1233

Query: 91   QGEPGLPGPPGPS---AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP 147
            QG PG PG PGP+     G PG  G PG+PG  GP GP G  G  G+ G +G PG PG+P
Sbjct: 1234 QGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1293

Query: 148  GPAGI-SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLP 205
            G  G+    G PG QG  G PG  G  G+ G PGVPG  G KG  G  G+ G  GE GL 
Sbjct: 1294 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1353

Query: 206  GPQGPTGPSGPPG-----VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGP 260
            GP GP G  GP G      G  G  G+PGQPG+K   G PG  GP G PGP GPPG+ G 
Sbjct: 1354 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLK---GLPGPQGPQGLPGPTGPPGDPGR 1410

Query: 261  EGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPG 305
             G+  PG  GA G+ G PG  G PG  G+ GPPGP G  G PG PG
Sbjct: 1411 NGL--PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454



 Score =  214 bits (546), Expect = 2e-55
 Identities = 137/328 (41%), Positives = 160/328 (48%), Gaps = 65/328 (19%)

Query: 264 GKPGAAGA-----PGQP----GIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314
           G+P  A A     PG      GI G KG  G PG+ G         PGLPG  G  GP  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG--------HPGLPGFPGPEGP-- 70

Query: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374
               PG +G++G  G+PG PG   P G  GP G  G PG+ GLPG  G  G  GP G PG
Sbjct: 71  ----PGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG------VGGPPGLPGPVGPAG 428
             G +G  G  G PG+PG   L GP G PG+PG KG+PG      + GP G PG  GP G
Sbjct: 124 CNGTKGERGFPGSPGFPG---LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 429 AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGS-----------KGDPGSPGPPGP 477
            +G+PG  G  GP G PG PG  GP GPPG+PG  G+           KG+ G  GPPGP
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 478 AGIAT--------------KGLNGPTGPPGPPGPRGHSGEP-GLPGPPGPPGPPGQAVMP 522
            G  +              +GL G  GPPGPPG RG  G P G  G  G  G PG+   P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 523 EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
               + GQ P + G P    + G  G P
Sbjct: 301 GKDGENGQ-PGIPGLP---GDPGYPGEP 324


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  460 bits (1183), Expect = e-129
 Identities = 266/545 (48%), Positives = 297/545 (54%), Gaps = 67/545 (12%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV-GKPGVPGL 113
            +GE G PGPPGP+GPRG PG  G PG  G  G+PG  GE G PG PGP    GK G  G 
Sbjct: 557  QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616

Query: 114  PGKPGERGPYGPKGDVGPAG------LPGPRGPPGP---PGIPGPAG-ISVPGKPGQQGP 163
             G PG  GP G KGD GP G      LPG  GPPG    PG PGP G    PG PG +G 
Sbjct: 617  QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 164  TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV-GKR 222
             GAPG RG PG  GAPG+ G        G G PG  G +G  GP GP G +G PG+ G  
Sbjct: 677  AGAPGERGPPGLAGAPGLRG--------GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP 728

Query: 223  GENGVPGQPGIKGDRG---------FPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPG 273
            GE G  G PG KGD+G          PG+ GP GP GP GPPG  G  G    G  GAPG
Sbjct: 729  GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG--DKGEGGAPG 786

Query: 274  QPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK 333
             PGI G +G PG  G  GPPGP GF  PG PG  GE G  G  G PG KGE GP G+ G 
Sbjct: 787  LPGIAGPRGSPGERGETGPPGPAGF--PGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 334  PGLTGPPGNMGPQGPKG------------IPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381
            PG +GP G  GPQG KG             PG+ GLPGP G  G  GP G  G+ G+ G 
Sbjct: 845  PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904

Query: 382  PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPA---GAKGMPGHNGE 438
            PG  G  G PG PG+ GPKG+ G PG KG PG  GPPG PGP+G A   GA+G+ G  G 
Sbjct: 905  PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM 964

Query: 439  AGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA----------TKGLNGP 488
             GPRG+PG  G +G  G PG  G  G +G PG  G PG AG A          + GL G 
Sbjct: 965  PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGR 1024

Query: 489  TGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGTPLVSAN 543
             G PG  G RG +G PG PG PG PGPPG  V P G  K+G R        +G P  + +
Sbjct: 1025 DGSPGGKGDRGENGSPGAPGAPGHPGPPG-PVGPAG--KSGDRGESGPAGPAGAPGPAGS 1081

Query: 544  QGVTG 548
            +G  G
Sbjct: 1082 RGAPG 1086



 Score =  446 bits (1146), Expect = e-125
 Identities = 289/631 (45%), Positives = 315/631 (49%), Gaps = 134/631 (21%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGS 87
           PTG     P   +  +  Y +KS G+AV G  G PGP GP GP G PG SG PG PG  S
Sbjct: 145 PTG-----PQNYSPQYDSYDVKS-GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPG--S 196

Query: 88  PGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP 147
           PG QG PG PG  GPS     G PG PG  G  GP G  G+ G  G PG RG PGPPGI 
Sbjct: 197 PGYQGPPGEPGQAGPS-----GPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIK 251

Query: 148 GPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAP----GRPGERG 203
           GPAGI  PG PG +G  G  G  G  GE GAPG+ G NG  GE G   P    G PGERG
Sbjct: 252 GPAGI--PGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG 309

Query: 204 LPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPG------EMGPIGPPGPQGPPGE 257
            PG  G  G  G  G   RG +G PG PG  G  GFPG      E+GP G PG  G PG+
Sbjct: 310 RPGLPGAAGARGNDGA--RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ 367

Query: 258 RGPEGI-GKPGAAGAPGQPGI---PGTKG------LPGAPGIAGPPGPPG----FGKPGL 303
           RG  G  G  GA G PG PGI   PG KG      +PGAPG+ G  GPPG     G PGL
Sbjct: 368 RGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL 427

Query: 304 ---------------PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTG---------P 339
                          PG +GERG AG+PG PGAKGE G  G PG+PG  G          
Sbjct: 428 RGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487

Query: 340 PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAG---------YPGAKGERG------SPGS 384
           PG  GP GP GIPG  G  G +G  GPAGP G          PG  G RG       PGS
Sbjct: 488 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 385 DGKPGYPGK---------PGLDGPKGNPGL---PGPKGD---------------PGVGGP 417
           DGKPG PG          PG  GP+G PG+   PGPKG+               PG  GP
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607

Query: 418 PGL---------PGPVGPAGAKG---------MPGHNGEAGPRGAPGIPGTRGPIGPPGI 459
           PG          PGP GP G KG         + G  G  GP G  G PG  GP G  G 
Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA 667

Query: 460 PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519
           PG PG KGD G+PG  GP G+A  G  G  G  GPPGP G  G  G PGPPG  G PG  
Sbjct: 668 PGAPGGKGDAGAPGERGPPGLA--GAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQ 725

Query: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            MP      G+R  L G+P    ++G  G P
Sbjct: 726 GMP------GERGGL-GSPGPKGDKGEPGGP 749



 Score =  442 bits (1136), Expect = e-124
 Identities = 260/551 (47%), Positives = 290/551 (52%), Gaps = 79/551 (14%)

Query: 59  QGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGL----P 114
           Q    P  P   +G  GP G PG PG   PG  G+PG+PG PG  + G PG PG+    P
Sbjct: 90  QPPTAPTRPPNGQGPQGPKGDPGPPGI--PGRNGDPGIPGQPG--SPGSPGPPGICESCP 145

Query: 115 GKPGERGPYGPKGDV-------GPAGLPGPRGPPGPPGIPGPAG-ISVPGKPGQQGPTGA 166
             P    P     DV       G AG PGP GPPGPPG PG +G    PG PG QGP G 
Sbjct: 146 TGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGE 205

Query: 167 PGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV------ 219
           PG  G  G  G PG  G +G  G+ G  G PGRPGERGLPGP G  GP+G PG       
Sbjct: 206 PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265

Query: 220 ----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQP 275
               G+ GE G  G PG+KG+ G PGE G  GP GP+G PGERG  G+  PGAAGA G  
Sbjct: 266 RGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGL--PGAAGARGND 323

Query: 276 GIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLP---GGPGAKGEQGP----- 327
           G  G+ G PG P   GPPG  GF  PG PG KGE GPAG P   G PG +GE GP     
Sbjct: 324 GARGSDGQPGPP---GPPGTAGF--PGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG 378

Query: 328 -AGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDG 386
             G PG PG+ G PG  G  GP GIPG+ GL G +G  GPAG  G PG +G  G PG +G
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 387 K---------------PGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKG 431
                           PG PG  G DG  G+PG PG  G PG  G  G PG  GPAG  G
Sbjct: 439 AKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498

Query: 432 MPGHNGEAGPRGAPGIPGTRGPIGPP---GIPGFPGSKGDPGSPGPPG----PAGIATKG 484
           +PG  G AG RGAPG  G RG  G P   G+PG PG +G PGSPG PG    P    ++G
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQG 558

Query: 485 LNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGTPL 539
            +G  GPPGP GPRG  G  G PGP G  G PG         K G+R     P   G P 
Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPG---------KNGERGGPGGPGPQGPPG 609

Query: 540 VSANQGVTGMP 550
            +   G  G P
Sbjct: 610 KNGETGPQGPP 620



 Score =  433 bits (1113), Expect = e-121
 Identities = 264/587 (44%), Positives = 293/587 (49%), Gaps = 95/587 (16%)

Query: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVPG 112
           G  G PG PG  G RG PGP+G  G PG     G PG  G  G PGP G    G+ G+PG
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER--GEAGIPG 456

Query: 113 LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS-VPGKPGQQGPTGAPGPRG 171
           +PG  GE G  G  G+ G  GLPG  G  G PG  GPAG + +PG+ G  G  GAPGP G
Sbjct: 457 VPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAG 516

Query: 172 ------FPGEKGAPGVPGMNGQKGEMGY-------GAPGRPGERGLPGPQGPTGPSGPPG 218
                  PG  G PG PGM G  G  G        G PG  GE G PGP GP+GP G PG
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPG 576

Query: 219 V-------------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG------ 259
           V             GK GE G PG PG +G  G  GE GP GPPGP GP G++G      
Sbjct: 577 VMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG 636

Query: 260 PEGI-------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGL---PGLKG 308
           P+G+       G PG  G PG+PG  G  G PGAPG  G  G PG  G PGL   PGL+G
Sbjct: 637 PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRG 696

Query: 309 ERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGN---MGPQGPKG------------IPG 353
             GP G  GG GA G  GP G  G PGL G PG    +G  GPKG            +PG
Sbjct: 697 GAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPG 756

Query: 354 SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDG------KPGYPGKPGLDGPKGNPGLPG 407
             G  GP G  GP GPAG PG KGE G+PG  G       PG  G+ G  GP G PG PG
Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG 816

Query: 408 PKGDPG------------VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP------GIPG 449
             G+PG             GGPPG+ GP G +G  G PG  G  G RG+P      G PG
Sbjct: 817 QNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPG 876

Query: 450 TRGPIGPPGI---PGFPGSKGDPGSPGPPGPAG-IATKGLNGPTGPPGPPGPRGHSGEPG 505
            RG  GPPG    PG PG  G PG  GPPGPAG     G  G +GP G  G  G  G PG
Sbjct: 877 ARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG 936

Query: 506 LPGPPGPPGPPGQAVM--PEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
             GPPG PGP G A +    G       P   G+P     +G +G P
Sbjct: 937 AQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP 983



 Score =  394 bits (1013), Expect = e-109
 Identities = 237/522 (45%), Positives = 266/522 (50%), Gaps = 92/522 (17%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPG------LPGPPGPSAV-GKPG 109
            G +G  GPPGP G +G  GP GPPG  G  +PGLQG PG       PGP G     G PG
Sbjct: 693  GLRGGAGPPGPEGGKGAAGPPGPPGAAG--TPGLQGMPGERGGLGSPGPKGDKGEPGGPG 750

Query: 110  VPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGP 169
              G+PGK G RGP GP G  GPAG PG +G  G PG+PG AG    G PG++G TG PGP
Sbjct: 751  ADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR--GSPGERGETGPPGP 808

Query: 170  RGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGV 227
             GFPG  G  G PG  G++G  G  G  G PG  G PG  GP GP GP GV G+RG  G 
Sbjct: 809  AGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG 868

Query: 228  PGQPGIKGDRGFPGEMGPIG---PPGPQGPPGERGPEG----IGKPGA---------AGA 271
            PG  G  G RG PG  G  G   PPGP G PG+ GP G     G PG+         AG 
Sbjct: 869  PGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQ 928

Query: 272  PGQPGIPGTKGLPGAPG------------IAGPPGPPG-------------FGKPGLPGL 306
            PG+ G PG +G PGAPG            +AGPPG PG              GKPG  GL
Sbjct: 929  PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGL 988

Query: 307  KGERGP---------AGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL 357
             GERGP         AG  G PG  G  G  GLPG+ G  G  G+ G  G  G PG+ G 
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048

Query: 358  PGP------------KGETGPAGPAGYPGAKGERGSPGSDG------KPGYPGKPGLDGP 399
            PGP            +GE+GPAGPAG PG  G RG+PG  G      + G  G  G+ G 
Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108

Query: 400  KGNPGLPGPKGDPGVGG---------PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT 450
            +G PG PG  G PG  G         P G  GPVGP+G  G  G +G  GP G PG  G 
Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGN 1168

Query: 451  RGPIGPPGIPGFPGSKGDPGSPGPPGP--AGIATKGLNGPTG 490
            RG  G  G PG PG  G PG PG PGP   G+    + G  G
Sbjct: 1169 RGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210



 Score =  385 bits (989), Expect = e-107
 Identities = 225/480 (46%), Positives = 255/480 (53%), Gaps = 66/480 (13%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGL---------QGEPGLPGPPG 101
            G    G  G  GP GP GP G PGP+G PG  G  G+PGL          GE G  GPPG
Sbjct: 748  GPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPG 807

Query: 102  PSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQ 160
            P+   G PG  G PG  GERG  G KG+ GP G+ GP G  GP G PGP G+      G+
Sbjct: 808  PAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK-----GE 862

Query: 161  QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV- 219
            +G  G PG  GFPG +G PG PG NG  G    G  G PG+ G PGP G TG  G PGV 
Sbjct: 863  RGSPGGPGAAGFPGARGLPGPPGSNGNPGPP--GPSGSPGKDGPPGPAGNTGAPGSPGVS 920

Query: 220  GKRGENGVPGQPGIKGDRGFPGEMGPI------------GPPGPQGPPGERGPEGI---- 263
            G +G+ G PG+ G  G +G PG  GP+            GPPG  GP G  GP+G+    
Sbjct: 921  GPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGES 980

Query: 264  GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKG 323
            GKPGA G  G+ G PG +GLPG  G AG P     G+ G PG  G  G  G PGG G +G
Sbjct: 981  GKPGANGLSGERGPPGPQGLPGLAGTAGEP-----GRDGNPGSDGLPGRDGSPGGKGDRG 1035

Query: 324  EQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPG 383
            E G  G PG PG  GPPG +GP G           G +GE+GPAGPAG PG  G RG+PG
Sbjct: 1036 ENGSPGAPGAPGHPGPPGPVGPAGKS---------GDRGESGPAGPAGAPGPAGSRGAPG 1086

Query: 384  SDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMP---GHNGEAG 440
              G  G  G+    G +G  G+ G +G PG  G PG PGP G  GA G P   G  G  G
Sbjct: 1087 PQGPRGDKGE---TGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVG 1143

Query: 441  PRGAPGIPGTRG---PIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGP 497
            P G PG  GT G   PIGPPG  G  G +G  GSPG PG          GP GPPG PGP
Sbjct: 1144 PSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQP--------GPPGPPGAPGP 1195



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 35/74 (47%), Positives = 40/74 (54%), Gaps = 10/74 (13%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGP-----SAVGKPGV 110
            G+ GT G PGP GP   PGP G  G+ G  GSPG  G+PG PGPPG        VG   +
Sbjct: 1149 GKDGTSGHPGPIGP---PGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAI 1205

Query: 111  PGLPG-KPGERGPY 123
             G+ G K G   PY
Sbjct: 1206 AGIGGEKAGGFAPY 1219



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 22/51 (43%), Positives = 26/51 (50%), Gaps = 7/51 (13%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVG 106
            RG +G+PG P      G PGP GPPG PG    G+ G   + G  G  A G
Sbjct: 1172 RGSEGSPGHP------GQPGPPGPPGAPGPCCGGV-GAAAIAGIGGEKAGG 1215


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  459 bits (1181), Expect = e-129
 Identities = 282/617 (45%), Positives = 324/617 (52%), Gaps = 107/617 (17%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKGIAVR-GEQGTPGPPGPAGPRGHPG-----PSGPPGKP 83
            G+ GP P  K    IP    + G   R G +G PGPPG  GP+G PG     P GPPG P
Sbjct: 707  GLPGP-PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLP 765

Query: 84   GY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPG--PRGP 140
            G+ G+ G +G+ G PGPPGP   G+ G+ GLPG  G+ GP G  G +GP GLPG   +GP
Sbjct: 766  GFKGALGPKGDRGFPGPPGPP--GRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGP 823

Query: 141  PGPPGIPGPAGI----SVPGKPGQQGPTG--APGPRGFPGEKGAPGVPGMNGQKGEMGY- 193
            PGPPGIPGP G      +PG+ G  GP G   PGP   PGE+G+PG+PG  G  G  G  
Sbjct: 824  PGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP---PGERGSPGIPGAPGPIGPPGSP 880

Query: 194  ---------GAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKG---DR 237
                     G PG  GE G+ GP GP GP G PG     G +G++G+ GQPG+ G   ++
Sbjct: 881  GLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEK 940

Query: 238  GFPGEMGPIGPPGPQGP-----PGERGPEGI-------GKPGAAGAPGQPGIPGTKGLPG 285
            G  GE G  GPPGP  P      GE+G  G+       G  G  G PG PG PG  G PG
Sbjct: 941  GSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPG 1000

Query: 286  APGIAGPPGPPGF-GKPGL---PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
             PG  GP G PG  G+PGL   PGLKG  G  G PG  G +G  GP+G+PG+PG  G PG
Sbjct: 1001 LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPG 1060

Query: 342  NMGPQGPKGIP--GSHGLPGPKGETG----PAGPA--------------GYPGAKGERGS 381
              G +G  GI   G  GLPGPKGE G    P  P               G PGAKG+ G 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 382  PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGP------------VGPAGA 429
            PG  G PG PG  G+ GP GNPGLPG  G  G GG PG PGP             GPAG 
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180

Query: 430  KGMP-----------------GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472
            KG P                 G  G+ G  G PG PG  GP G PG  GFPG +G PG P
Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 473  GPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRP 532
            G PGPA    KG  GP GPPG PGP G     GLPGP GPPG PG   +       GQ P
Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGPTGFQ---GLPGPEGPPGLPGNGGIKGEKGNPGQ-P 1296

Query: 533  SLSGTPLVSANQGVTGM 549
             L G P +  +QG  G+
Sbjct: 1297 GLPGLPGLKGDQGPPGL 1313



 Score =  459 bits (1180), Expect = e-129
 Identities = 276/586 (47%), Positives = 305/586 (52%), Gaps = 126/586 (21%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGL---------QGEPGLPGPPGP 102
            +GE G  GPPGP GP G PG SG PG  G     G PGL         +GEPGLPGPPGP
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 103  ---------SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGL------PGPRGPPGPPGIP 147
                        G+PG+PG+PG  G +G  G  GD G  GL      PGP GP G PG+P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 148  GPAGISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPG 197
            G  G+  P          G PG QG  G PGP G PG+ G+PG+PG  G KG+ G  + G
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 198  RPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250
             PG   LPGP+G  G  G PG       VG  G  G+PG PG KG  G PG  G  GPPG
Sbjct: 1075 LPG---LPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPG 1131

Query: 251  PQG---PPGERG-PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP------PGPPGFGK 300
            P+G   PPG  G P   G  G  G PGQPG PG KG PG  GI GP      PG PGFG 
Sbjct: 1132 PKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGN 1191

Query: 301  PG---LPGLKGERGPAGLPGGPG------AKGE---------QGPAGLPGKPG--LTGPP 340
            PG   LPGL G++G  GLPG PG       KGE         QGP G PG PG  L GP 
Sbjct: 1192 PGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPK 1251

Query: 341  GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG------KP 394
            GN GPQGP G PG  G  G  G  GP G  G  G KGE+G+PG  G PG PG       P
Sbjct: 1252 GNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1311

Query: 395  GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG---PRGAPGIPGT- 450
            GL G  G PGL G KGDPG+ G PG PG  GP+G  G  G  GE G   P G PG+PG  
Sbjct: 1312 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPS 1371

Query: 451  ------RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG----- 499
                  +G  GPPGIPG PG KG PG  GP        +GL GPTGPPG PG  G     
Sbjct: 1372 GQSIIIKGDAGPPGIPGQPGLKGLPGPQGP--------QGLPGPTGPPGDPGRNGLPGFD 1423

Query: 500  ----HSGEPGLPGPPG---------------PPGPPGQAVMPEGFI 526
                  G+PGLPG PG               PPGPPG + +  GF+
Sbjct: 1424 GAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFL 1469



 Score =  452 bits (1164), Expect = e-127
 Identities = 271/602 (45%), Positives = 313/602 (51%), Gaps = 117/602 (19%)

Query: 52   GIAVRGEQGTPGPPGPAGP---RGHPGPSGPPGKPGY---GSPGLQGEPGLPGPPGPSAV 105
            GI V+G  G PG PGP G     G PG  G PG PG    G PG +G PG+PG PGP  +
Sbjct: 817  GIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGP--I 874

Query: 106  GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI-------SVPGKP 158
            G PG PGLPGK G  G  G KG++G   + GP GPPGP GIPG +G+        + G+P
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMG---MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQP 931

Query: 159  GQQGPTGAPGPRGFPG-----------------EKGAPGVPGMNGQKGEMGY----GAPG 197
            G  GPTG  G +G PG                 EKG PG+PG+ G  G  GY    G PG
Sbjct: 932  GLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPG 991

Query: 198  RPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPG 256
            +PG  G PG  GP GP G PG+ G+ G  G PG  G  GD GFPG  G  GPPGP G PG
Sbjct: 992  QPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG 1051

Query: 257  ERGPEGI-GKPGAAGAPG-----QPGIPGTKGLPGAPGIAGPPGPPGF----GKPGLPGL 306
            + G  G+ G+ G  G PG      PG+PG KG PG PG  G PG  G     G PGLPG 
Sbjct: 1052 QPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGT 1111

Query: 307  KGERGPAGLPGGPGAKGEQGPAGL---PGKPGLTGPPGNMG---------PQGPKGIPGS 354
             G +G  GLPG PG  G  GP G+   PG PGL G PG +G         P G KG PG 
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 355  HGLPGPKGETGPAGPAGY-----PGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG----- 404
             G+PGP G+ G  G  G+     PG  G  G  G  G PG PG PGL GPKG PG     
Sbjct: 1172 DGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFP 1231

Query: 405  ---------------LPGPKGDPGVGGPPGLPGPVG------PAGAKGMPGHNGEAGPRG 443
                           L GPKG+PG  GPPG PGP G      P G  G+PG+ G  G +G
Sbjct: 1232 GVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKG 1291

Query: 444  ------APGIPGTRGPIGPPGI------PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGP 491
                   PG+PG +G  GPPG+      PG  G KGDPG PG PG       G+ GP+G 
Sbjct: 1292 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG-----FPGMKGPSGV 1346

Query: 492  PGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQ-----RPSLSGTPLVSANQGV 546
            PG  GP G  G  G PGPPG PGP GQ+++ +G   AG      +P L G P     QG+
Sbjct: 1347 PGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG--DAGPPGIPGQPGLKGLPGPQGPQGL 1404

Query: 547  TG 548
             G
Sbjct: 1405 PG 1406



 Score =  446 bits (1146), Expect = e-125
 Identities = 267/592 (45%), Positives = 299/592 (50%), Gaps = 84/592 (14%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKG----IAVRGEQGTPGPPGPAGPRGHPGPSGPPG--KP 83
            G+ G LP T  Q  +P     KG    I  +GE+G PG PG  G  G+ GP GPPG   P
Sbjct: 570  GLPG-LPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 84   G----YGSPGLQGEPGLPGPPGPSA-----VGKPGVPGLPGKPGERGPYGPKGDVGPAGL 134
            G     G  G+ G PG PG PGP       + +PG PGLPG PG  G  G  GD G  G 
Sbjct: 629  GPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ 688

Query: 135  PGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE------KGAPGVPGMNGQK 188
            PG  G PG  G PG  GI +PG PG +G  G PGP G PG       +G PG PG  G K
Sbjct: 689  PGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPK 748

Query: 189  GEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGP 248
            GE G+  PG PG  GLPG +G  GP        +G+ G PG PG  G  G  G  GP G 
Sbjct: 749  GEPGFALPGPPGPPGLPGFKGALGP--------KGDRGFPGPPGPPGRTGLDGLPGPKGD 800

Query: 249  PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP---GAPGIAGPPGPPGFGKPGLPG 305
             GP G PG  GP G+   G  G PG PGIPG  G P   G PG  G PGPPG   PG P 
Sbjct: 801  VGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP- 859

Query: 306  LKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNM---------GPQGPKGIPGSHG 356
              GERG  G+PG PG  G  G  GLPGK G +G PG           GP GP GIPG  G
Sbjct: 860  --GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSG 917

Query: 357  LPGPKGETGPAGPAGYPGAKGER--------------------GSPGSDGKPGYPGKPGL 396
            +PG KG+ G  G  G PG  GE+                    GS G  G+PG PG PG+
Sbjct: 918  VPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGV 977

Query: 397  DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP---------RGAPGI 447
             GPKG  GLPG  G PG+ G PGLPGP GP G  G+PG  G  GP          G PG 
Sbjct: 978  SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 448  PGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGP---------PGPPGPR 498
             G  GP GP G+PG PGS G PG  G  G  GI++ GL G  GP         PG PG +
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G  G+PGLPG PG PG  GQ  +P GF      P   G      N G+ G P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLP-GFPGTPGPPGPKGISGPPGNPGLPGEP 1148



 Score =  423 bits (1088), Expect = e-118
 Identities = 288/726 (39%), Positives = 327/726 (45%), Gaps = 221/726 (30%)

Query: 28  PTGIKGP--LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY 85
           P GI+GP  LP        P T    G+   G  G PGP G  G  G  G  G PG PG+
Sbjct: 88  PKGIRGPPGLPG------FPGTPGLPGMP--GHDGAPGPQGIPGCNGTKGERGFPGSPGF 139

Query: 86  GSPGLQGEPGLPGPPG-------------PSAVGKPGVPGLPGKPGERGPYGPKGDVGPA 132
             PGLQG PG PG PG             P   G PG PG PG  G  GP G  G +GP 
Sbjct: 140 --PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPP 197

Query: 133 GLPGPRGPPGPPGIPGPAG------ISVPGKPGQQGPTGAPGP----------------- 169
           G PG  GPPGPPG+PGP G          G+ G+QG  G PGP                 
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 170 --RGFPGEKGAPGVPGM----------NGQKGEMGY------------------------ 193
             +G PG++G PG PG+           G+KGE G                         
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGD 317

Query: 194 -GAPGRPGERGLPGPQGPTGPSGPPG-----------VGKRGENGVPGQPGIKGDRGFPG 241
            G PG PG  G  G +G TGP GPPG           +G++G  G+PG PG KG+RGFPG
Sbjct: 318 PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPG 377

Query: 242 EMGP-----------IGPPGPQGPPGERGPEGIGKPGAAGAPGQPGI---PGTKGLPGAP 287
             GP           +GPPGP G PGERG +G   P     PG PG+   PG  GLPG P
Sbjct: 378 IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPP 437

Query: 288 GIAGP----------PGPPGFGKPGLPGLKGERGPAGLPGGPG-------AKGEQGPAGL 330
           G AGP          PGPP  G PG PG KG +G  G+ G  G         G  GP G 
Sbjct: 438 GPAGPHIPPSDEICEPGPP--GPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 331 PGKPGLTGPPGNM------------GPQGPKGIPGSHGLPGPKGETGPAGPAG----YPG 374
           PG PGL GPPG++            G  GPKG+PG  G PG  G  G  G  G    +PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP------GVGGPPGLP------- 421
            KG++G  GS G PG PG PG  G  G PGLPGPKG+P      G  GPPG P       
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 422 ----------GPVGPAGAKGM------PGHNGEAGPRGAP-------------------- 445
                     GP GP G KG+      PG  G  GP+G P                    
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 446 --GIPGTRGPIGPPGIPGFPGSKGDP-----GSPGPPGPAGI----------ATKGLNGP 488
             G+PG  G  G PG+PG PGSKG+P     G PGPPGP G            T G  G 
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 489 TGPPGPPGPRGHSGEPG--LPGPPGPPGPPG--QAVMPEGFIKAGQRPSLSGTPLVSANQ 544
            GPPGPPG  G  GEPG  LPGPPGPPG PG   A+ P+G           G P      
Sbjct: 736 EGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKG------DRGFPGPPGPPGRT 789

Query: 545 GVTGMP 550
           G+ G+P
Sbjct: 790 GLDGLP 795



 Score =  389 bits (998), Expect = e-108
 Identities = 266/652 (40%), Positives = 299/652 (45%), Gaps = 200/652 (30%)

Query: 89  GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
           G++GE G  G PG    G PG+PG PG  G  GP G KGD G  G PGP+G  GPPG+PG
Sbjct: 42  GIKGEKGERGFPGLE--GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPG 99

Query: 149 PAGISVPGKPGQQGPTGAPGPR------------------GFPGEKGAPGVPGMNGQKGE 190
             G   PG PG  G  GAPGP+                  GFPG +G PG PG+ G KGE
Sbjct: 100 FPG--TPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGE 157

Query: 191 MGY-------------GAPGRPGERGLPGP---QGPTGPSGPPGV--------------- 219
            G              G PG PG +GLPGP    GP GP GPPG+               
Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGN 217

Query: 220 ---------GKRGENGVPGQPG----------------IKGDRGFPGEMGPIGPPGPQGP 254
                    G++GE G+ G PG                 KGD+G PG+ GP GPPG +GP
Sbjct: 218 MGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGP 277

Query: 255 P-------GERGPEG----IGKPGAAGAPGQPGIPGTKGLPGAP------------GIAG 291
           P       GE+G +G     GKPG  G  GQPGIPG  G PG P            G  G
Sbjct: 278 PGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTG 337

Query: 292 PPGPPG-----------------FGKPGLPGLKGER------GPAGLPGGPGA--KGEQG 326
           PPGPPG                  G PGLPG KGER      GP GLPG PGA   G  G
Sbjct: 338 PPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPG 397

Query: 327 PAGLPGKPGL---TGPPGNM--GPQGPKGIPGSHGLPGPKG-------------ETGPAG 368
           P G PG+ G     GPPG    GP G  G PG+ GLPGP G             E GP G
Sbjct: 398 PPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPG 457

Query: 369 PAGYPGAKGERG----------------SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD- 411
           P G PG KG +G                  G  G PG PG PGL GP G+ G PG KG+ 
Sbjct: 458 PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEK 517

Query: 412 --PGVGGPPGLPGPVGPAGAKGMP----------------GHNGEAGPRGAPGIPGTRGP 453
              G  GP GLPG  G  GA G P                G  GE G  GAPG+PG  G 
Sbjct: 518 GQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGT 577

Query: 454 IGPPGIPGFPGSKGDP------GSPGPPGPAGI-ATKGLNGPTGPP--GPPGP------R 498
            G  G+PG PG KG+P      G  GPPG  G+    G  GP GPP  GPPGP      +
Sbjct: 578 PGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G +G PG PG PGP G PGQ +   G      +P L G P    + G+ G P
Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPG------KPGLPGNPGRDGDVGLPGDP 683



 Score =  214 bits (546), Expect = 2e-55
 Identities = 137/328 (41%), Positives = 160/328 (48%), Gaps = 65/328 (19%)

Query: 264 GKPGAAGA-----PGQP----GIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAG 314
           G+P  A A     PG      GI G KG  G PG+ G         PGLPG  G  GP  
Sbjct: 21  GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEG--------HPGLPGFPGPEGP-- 70

Query: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374
               PG +G++G  G+PG PG   P G  GP G  G PG+ GLPG  G  G  GP G PG
Sbjct: 71  ----PGPRGQKGDDGIPGPPG---PKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPG 123

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG------VGGPPGLPGPVGPAG 428
             G +G  G  G PG+PG   L GP G PG+PG KG+PG      + GP G PG  GP G
Sbjct: 124 CNGTKGERGFPGSPGFPG---LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPG 180

Query: 429 AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGS-----------KGDPGSPGPPGP 477
            +G+PG  G  GP G PG PG  GP GPPG+PG  G+           KG+ G  GPPGP
Sbjct: 181 IQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGP 240

Query: 478 AGIAT--------------KGLNGPTGPPGPPGPRGHSGEP-GLPGPPGPPGPPGQAVMP 522
            G  +              +GL G  GPPGPPG RG  G P G  G  G  G PG+   P
Sbjct: 241 PGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP 300

Query: 523 EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
               + GQ P + G P    + G  G P
Sbjct: 301 GKDGENGQ-PGIPGLP---GDPGYPGEP 324


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  452 bits (1163), Expect = e-127
 Identities = 271/586 (46%), Positives = 305/586 (52%), Gaps = 114/586 (19%)

Query: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPG---LPGPPGPS-------AV 105
           G +G  GP GP GP G  G SG PG PG  G  G +GEPG   + GPPGP+       A 
Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 106 GKPGVPGLPGKPGERGP------------YGPKGDVGPAGLPGPRGPPGPPG-------- 145
           G+PG  GLPG PGERG              GPKG  G  G PGP GP G PG        
Sbjct: 473 GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEA 532

Query: 146 -IPGPAGIS-VPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-------GAP 196
            +PG  G++  PG PG  G TG PGP G  G  G PG PG  GQ G MG+       G P
Sbjct: 533 GLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEP 592

Query: 197 GRPGERGLPGPQGPTGPSG---------PPG----VGKRGENGVPGQPGIKGDRGFPGEM 243
           G+ GERG+PGP G  GP+G         PPG     G+RGE G  G PG      F G  
Sbjct: 593 GKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG------FQGLP 646

Query: 244 GPIGPPGPQGPPGERG-PEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP---------- 292
           GP GPPG  G PGE+G P  +G PG +GA G+ G PG +G+ G PG AGP          
Sbjct: 647 GPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGND 706

Query: 293 --------PGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNM 343
                   PG PG  G PGL G+ GERG AGLPG  G +G+ GP G  G PG  G  G  
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLT 766

Query: 344 GPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKG---ERGSPGSDGKPGYPGKPGLDGP- 399
           GP GP   PG  G PG KGE+GP+GPAG  GA+G   +RG PG  G  G+ G PG DG  
Sbjct: 767 GPIGP---PGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823

Query: 400 --KGNPGLPGPKGD---PGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
             KG PG  G KGD   PG  GP G PGP+G  GA G  G  G AGP GA G PG  G +
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883

Query: 455 GPPGIPGFPGSKGDPGSPGPPGPAG----------IATKGLNGPTGPPGPPGPRGHSGEP 504
           GPPG        G+ G PGPPGPAG              G  G  GPPGPPGP G  G P
Sbjct: 884 GPPG------PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSP 937

Query: 505 GLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G  GP G PG PG    P+G   AGQR  + G P     +G  G+P
Sbjct: 938 GADGPAGAPGTPG----PQGI--AGQR-GVVGLPGQRGERGFPGLP 976



 Score =  441 bits (1135), Expect = e-124
 Identities = 272/615 (44%), Positives = 303/615 (49%), Gaps = 124/615 (20%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------------GSPGLQGEPGLPGPPGP- 102
            G  G  GPPGPAG  G PGP GPPG  G              G PG  GE G+PGPPG  
Sbjct: 548  GPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAV 607

Query: 103  SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKP 158
               GK G  G  G PG  GP G +G+ GPAG PG +G PGP G PG AG      VPG  
Sbjct: 608  GPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL 667

Query: 159  GQQGPTGAPGPRGFPGEKG------------APGVPGMNGQKGEMG-------YGAPG-- 197
            G  GP+GA G RGFPGE+G            A G PG +G KG+ G        GAPG  
Sbjct: 668  GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQ 727

Query: 198  -RPGERG---LPGPQGPTGPSGPPGV-GKRGENGV---------PGQPGIKGDRGFPGEM 243
              PGERG   LPGP+G  G +GP G  G  G++GV         PG  G  GD+G  G  
Sbjct: 728  GMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPS 787

Query: 244  GPIGPPGPQGPPGERGPEG-------IGKPGAAGAPG---QPGIPGTKGLPGAPGIAGPP 293
            GP GP G +G PG+RG  G        G PGA G PG   +PG  G KG  G PG AGP 
Sbjct: 788  GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPA 847

Query: 294  GPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIP 352
            GPPG  G  G PG KG RG AG PG  G  G  G  G PG  G  GPPG  GP G +G  
Sbjct: 848  GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK 907

Query: 353  GSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD--------------- 397
            G  G  GP G  G  GP G PG  GE+GSPG+DG  G PG PG                 
Sbjct: 908  GPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQR 967

Query: 398  GPKGNPGLPGPKGDPGVGGPPGL------PGPVGPAGAKGMPGHNGEAGPRGAPGIP--- 448
            G +G PGLPGP G+PG  GP G       PGP+GP G  G PG +G  G  GA G P   
Sbjct: 968  GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027

Query: 449  ---------GTRGPIGPPGIPGFPGS---------KGDPGSPGPPGPAG-IATKGLNGPT 489
                     G  GP GPPG PG PG+          GD G  GP GPAG +   G  GP 
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPA 1087

Query: 490  GPPGPPGPRGHSGE------------PGLPGPPGPPGPPGQAVMPEGFIKAGQR--PSLS 535
            GP GP G +G +GE             GL GPPGPPG PG+         AG R  P  +
Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147

Query: 536  GTPLVSANQGVTGMP 550
            G P      G+ G+P
Sbjct: 1148 GAP---GKDGLNGLP 1159



 Score =  439 bits (1130), Expect = e-123
 Identities = 252/512 (49%), Positives = 272/512 (53%), Gaps = 58/512 (11%)

Query: 57   GEQGTPGPPGPAGPRGH---------PGPSGPPGKPG-YGSPGLQGEPG------LPGPP 100
            GE+G  GPPGPAGPRG           G +G PG PG  G+PGLQG PG      LPGP 
Sbjct: 683  GERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPK 742

Query: 101  GPSA-VGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPG 159
            G     G  G  G PGK G RG  GP G  GPAG PG +G  GP G  GP G    G PG
Sbjct: 743  GDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR--GAPG 800

Query: 160  QQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG- 218
             +G  G PGP GF G  GA G PG  G+ G+ G       G+ G PGP GP GP GP G 
Sbjct: 801  DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAG-----AKGDAGPPGPAGPAGPPGPIGN 855

Query: 219  VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG---PPGERGPEG------------- 262
            VG  G  G  G  G  G  GFPG  G +GPPGP G   PPG  GP G             
Sbjct: 856  VGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP 915

Query: 263  IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPGLPGLKGERGPAGLPGG 318
             G+PG  G PG PG  G KG PGA G AG PG PG     G+ G+ GL G+RG  G PG 
Sbjct: 916  AGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL 975

Query: 319  PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
            PG  GE G  G  G  G  GPPG MGP G  G PG  G  G  G  G  G  G PGAKG+
Sbjct: 976  PGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD 1035

Query: 379  RGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVG---PAGAKGMPGH 435
            RG  G  G PG PG PG  GP G  G  G +G+ G  GP G  GPVG   PAG +G  G 
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095

Query: 436  NGEAGPRGAPGIPGTRG------PIGPPGIPGFPGSKGDPGSPGPPGPAGIA----TKGL 485
             GE G +G  GI G RG      P GPPG PG  G  G  G  GP GP G A      GL
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155

Query: 486  NGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517
            NG  GP GPPGPRG +G+ G  GPPGPPGPPG
Sbjct: 1156 NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG 1187



 Score =  433 bits (1114), Expect = e-121
 Identities = 268/574 (46%), Positives = 305/574 (53%), Gaps = 70/574 (12%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKG-IAVRGEQGTPGPPGPAGPRGHPGP---SGPPGKP 83
           P G  G   N   Q    Y  KS G I+V G  G  GP G  GP G PGP    GPPG+P
Sbjct: 149 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP 208

Query: 84  GY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD---VGPAGLPGPRG 139
           G  G+ G  G  G PGPPG +  G  G  G PG+PGERGP GP+G     G AGLPG +G
Sbjct: 209 GEPGASGPMGPRGPPGPPGKN--GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266

Query: 140 PPGPPGI------PGPAG-ISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG 192
             G  G+       GPAG    PG PG+ G  G  GPRG PGE+G PG PG         
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPG--------P 318

Query: 193 YGAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKGDRGFPGEMGPIGP 248
            GA G  G  G  GP GPTGP+GPPG    VG +GE G  G  G +G +G  GE GP GP
Sbjct: 319 AGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGP 378

Query: 249 PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------FGKP 301
            G  GP G  G +  G+PGA GA G PGI G  G PGA G +GP GP G        G+P
Sbjct: 379 AGAAGPAGNPGAD--GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEP 436

Query: 302 GLP------GLKGERGPAGLPGGPGAKGEQGPAGLPGKP---GLTGPPGNMGPQGPKGIP 352
           G P      G KGE GP G+ G PG  GE+G  G  G+P   GL GPPG  G  G +G P
Sbjct: 437 GAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP 496

Query: 353 GSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP---K 409
           G+ G+ GPK   GPAG  G PG  G +GSPG  G+PG  G PG  G  G+PG PGP    
Sbjct: 497 GADGVAGPK---GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT 553

Query: 410 GDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA---PGIPGTRGPIGPPGIPGFPGSK 466
           G PG  G  G PGP GP GA+G  G  G  GP+GA   PG  G RG  GPPG  G  G  
Sbjct: 554 GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD 613

Query: 467 GDPGSPGPPGPAGIA----------TKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPP 516
           G+ G+ GPPGPAG A          + G  G  GP GPPG  G  GE G+PG  G PGP 
Sbjct: 614 GEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPS 673

Query: 517 GQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G A    GF   G+R  + G P  +  +G  G P
Sbjct: 674 G-ARGERGF--PGER-GVQGPPGPAGPRGANGAP 703



 Score =  432 bits (1110), Expect = e-121
 Identities = 261/579 (45%), Positives = 293/579 (50%), Gaps = 89/579 (15%)

Query: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGL-------------- 96
           V G +G  GP GP GP G PG  G PG+PG     G PG  G PGL              
Sbjct: 110 VEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDE 169

Query: 97  --------PGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP 147
                   PGP GPS   G PG PG PG  G +GP G  G+ G +G  GPRGPPGPPG  
Sbjct: 170 KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKN 229

Query: 148 GPAG-ISVPGKPGQQGPTGAPGPRGFPGEKGAPGV------PGMNGQKGEMG----YGAP 196
           G  G    PG+PG++GP G  G RG PG  G PG+       G++G KG+ G     G P
Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP 289

Query: 197 GRPGERGLPGPQGPTG-------PSGPPGVGKRGENGV------PGQPGIKGDRGFPGEM 243
           G PGE G PG  GP G       P  P   G RG +G       PG  G  G  GFPG +
Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349

Query: 244 GPIGPPGPQGPPGERGPEGI----GKPGAAGA------PGQPGIPGTKGLPGAPGIAGPP 293
           G  G  GPQGP G  GP+G+    G PG AGA      PG  G PG KG  GAPGIAG P
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409

Query: 294 GPPGFGKPGLP----GLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPK 349
           G PG   P  P    G  G +G +G PG PG+KG+ G  G PG  G+ GPPG  G +G +
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469

Query: 350 GI---PGSHGLPGPKGETGPAGPAGYPGA---------KGERGSPGSDGKPGYPGKPGLD 397
           G    PG  GLPGP GE G  G  G+PGA          GERGSPG  G  G PG+ G  
Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457
           G  G PG  G  G PG  GP G  GP GPAG  G PG  G  G RG  G+ G  GP G  
Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAA 589

Query: 458 GIPGFPGSKGDPGSPGPPGPAG-IATKGLNGPTGPPGPPGPRGH---SGEPGLPGPPGPP 513
           G PG  G +G PG PG  GPAG     G  GP GP GP G RG    +G PG  G PGP 
Sbjct: 590 GEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPA 649

Query: 514 GPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMP 550
           GPPG+A  P      G++  P   G P  S  +G  G P
Sbjct: 650 GPPGEAGKP------GEQGVPGDLGAPGPSGARGERGFP 682



 Score =  427 bits (1099), Expect = e-119
 Identities = 262/582 (45%), Positives = 288/582 (49%), Gaps = 127/582 (21%)

Query: 57   GEQGTPGPPGPAGP---------RGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPS 103
            GE+G PGPPG  GP         +G PGP+GP G+ G     GSPG QG PG  GPPG +
Sbjct: 596  GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655

Query: 104  AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS-VPGK----- 157
              GKPG  G+PG  G  GP G +G+    G PG RG  GPPG  GP G +  PG      
Sbjct: 656  --GKPGEQGVPGDLGAPGPSGARGE---RGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710

Query: 158  ----PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPGPQG 209
                PG  G  GAPG +G PGE+GA G+PG  G +G+ G     G+PG+ G RGL GP G
Sbjct: 711  DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG 770

Query: 210  PTGPSGPPG-------------------VGKRGENGVPG------------QPGIKGDRG 238
            P GP+G PG                    G RGE G PG            QPG KG+ G
Sbjct: 771  PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830

Query: 239  FPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGI-------- 289
              G  G  GPPGP GP G  GP G +G PGA GA G  G PG  G PGA G         
Sbjct: 831  DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890

Query: 290  -AGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP---PGNMG 344
             AGPPGPPG  GK G  G +GE GPAG PG  G  G  GPAG  G PG  GP   PG  G
Sbjct: 891  NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG 950

Query: 345  PQG------------------------PKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380
            PQG                        P G PG  G  G  GE GP GP G PG  G  G
Sbjct: 951  PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG 1010

Query: 381  SPGSDGKPGYPGKPGLDGP---KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNG 437
              G +G PG  G PG DG    KG+ G  GP G PG  G PG PGPVGPAG  G  G  G
Sbjct: 1011 ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETG 1070

Query: 438  EAGPRGAPGIPGTRGPIGPPGIPG------------------FPGSKGDPGSPGPPGPAG 479
             AGP G  G  G RGP GP G  G                  F G +G PG PG PG  G
Sbjct: 1071 PAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQG 1130

Query: 480  IATKGLNGPTGPPGPPGPRGHSGEPGL---PGPPGPPGPPGQ 518
                G +GP GP GPPG  G  G+ GL   PGP GPPGP G+
Sbjct: 1131 --PSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGR 1170



 Score =  419 bits (1078), Expect = e-117
 Identities = 241/541 (44%), Positives = 274/541 (50%), Gaps = 59/541 (10%)

Query: 60  GTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGK----------- 107
           G  GP G  GPRG  GP+GPPG+ G  G PGL G PG PGPPGP  +G            
Sbjct: 109 GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYD 168

Query: 108 ---------------------PGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146
                                PG PG PG  G +GP G  G+ G +G  GPRGPPGPPG 
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 147 PGPAG-ISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPG------MNGQKGEMG----YGA 195
            G  G    PG+PG++GP G  G RG PG  G PG+ G      ++G KG+ G     G 
Sbjct: 229 NGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGE 288

Query: 196 PGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPP 255
           PG PGE G PG  GP G  G     +RG  G PG  G +G+ G  G  GP GP GP GPP
Sbjct: 289 PGSPGENGAPGQMGPRGLPG-----ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343

Query: 256 GERGPEGI----GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGER 310
           G  G  G     G  G  G+ G  G+ G  G PG  G AGP G PG  G+PG  G  G  
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403

Query: 311 GPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPA 370
           G AG PG PGA+G  GP G  G PG  G  G  G  G KG  G+ G PGP G  GP GPA
Sbjct: 404 GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPA 463

Query: 371 GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK 430
           G  G +G RG PG  G PG PG+ G  G +G PG  G  G  G  G  G PGP GP G+ 
Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP 523

Query: 431 GMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI-ATKGLNGPT 489
           G  G  GEAG  GA G+ G+ G  GP G  G PG  G  G PGPPGP G     G+ G  
Sbjct: 524 GEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFP 583

Query: 490 GPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
           GP G  G  G +GE G+PGPPG  GP G+    +G   A   P  +G       QG  G 
Sbjct: 584 GPKGAAGEPGKAGERGVPGPPGAVGPAGK----DGEAGAQGPPGPAGPAGERGEQGPAGS 639

Query: 550 P 550
           P
Sbjct: 640 P 640



 Score =  402 bits (1033), Expect = e-112
 Identities = 237/534 (44%), Positives = 266/534 (49%), Gaps = 55/534 (10%)

Query: 60  GTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGE 119
           G   P G   P    G   P  +   G  G +G+ G  GP GP+  G PG  G+PG+PG 
Sbjct: 83  GAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPA--GPPGRDGIPGQPGL 140

Query: 120 RGPYGPKGDVGPAGL----------------------PGPRGPPGPPGIPGPAGISVPGK 157
            GP GP G  GP GL                      PGP GP GP G+PGP G   PG 
Sbjct: 141 PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPG--APGP 198

Query: 158 PGQQGPTGAPGPRGFP---GEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS 214
            G QGP G PG  G     G +G PG PG NG  GE   G PGRPGERG PGPQG  G  
Sbjct: 199 QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEA--GKPGRPGERGPPGPQGARGLP 256

Query: 215 GPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPG 273
           G  G+ G +G  G  G  G KGD G  G  G  G PG  G PG+ GP G+  PG  G PG
Sbjct: 257 GTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL--PGERGRPG 314

Query: 274 QPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGL------------KGERGPAGLPGGPG 320
            PG  G +G  GA G AGPPGP G  G PG PG             +G  GP G+ G PG
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374

Query: 321 AKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380
             G  G AG  G PG  G PG  G  G  GI G+ G PG +G +GP GP G PG KG  G
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434

Query: 381 SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG 440
            PG+ G  G  G  G  GP G  G PGP G+ G  G  G PGP G  G  G  G  G  G
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG 494

Query: 441 PRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI-ATKGLNGPTGPPGP---PG 496
             GA G+ G +GP G  G PG  G KG PG  G PG AG+   KGL G  G PGP    G
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554

Query: 497 PRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           P G +G+ G PGPPGPPG  GQA    G +        +G P  +  +GV G P
Sbjct: 555 PPGPAGQDGRPGPPGPPGARGQA----GVMGFPGPKGAAGEPGKAGERGVPGPP 604



 Score =  293 bits (750), Expect = 4e-79
 Identities = 173/378 (45%), Positives = 189/378 (50%), Gaps = 38/378 (10%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGS 87
            P G  GP+ N               +   G +G  G  GP G  G PG +G       G 
Sbjct: 846  PAGPPGPIGN---------------VGAPGAKGARGSAGPPGATGFPGAAG-----RVGP 885

Query: 88   PGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIP 147
            PG  G  G PGPPGP+     G  G  G  GE GP G  G+VGP G PGP G  G PG  
Sbjct: 886  PGPSGNAGPPGPPGPA-----GKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 148  GPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPG 206
            GPAG   PG PG QG  G  G  G PG++G  G PG+ G  GE G  G  G  GERG PG
Sbjct: 941  GPAG--APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998

Query: 207  PQGPTGPSGPPG----VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG 262
            P GP G +GPPG     G  G  G PG+ G  G +G  GE GP GPPG  G PG  GP G
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058

Query: 263  -IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGA 321
              GK G  G  G  G  G  G  GA G AGP GP G       G  GE+G  G+ G  G 
Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD-----KGETGEQGDRGIKGHRGF 1113

Query: 322  KGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381
             G QGP G PG PG  GP G  GP GP+G PGS G PG  G  G  GP G PG +G  G 
Sbjct: 1114 SGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGD 1173

Query: 382  PGSDGKPGYPGKPGLDGP 399
             G  G PG PG PG  GP
Sbjct: 1174 AGPVGPPGPPGPPGPPGP 1191



 Score =  158 bits (399), Expect = 2e-38
 Identities = 104/262 (39%), Positives = 119/262 (45%), Gaps = 61/262 (23%)

Query: 334 PGLTGPPGNMGPQGPKGIPG-----SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKP 388
           PG   P G   P  P G        + G+ GPKG+TGP GP         RG  G  G+ 
Sbjct: 82  PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGP---------RGPAGPPGRD 132

Query: 389 GYPGKPGLDGPKGNPGLPGPKGDPGVGG--PPGL--------------PGPVGPAGAKGM 432
           G PG+PGL GP   PG PGP G PG+GG   P L              PGP+GP+G +G+
Sbjct: 133 GIPGQPGLPGP---PGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL 189

Query: 433 PGHNGEAGPR------GAPGIPGTRGPIGPPGIPGFPGSKGD---------PGSPGPPGP 477
           PG  G  GP+      G PG PG  GP+GP G PG PG  GD         PG  GPPGP
Sbjct: 190 PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP 249

Query: 478 AGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ-----------AVMPEGFI 526
            G   +GL G  G PG  G RG SG  G  G  GP GP G+            + P G  
Sbjct: 250 QG--ARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP 307

Query: 527 KAGQRPSLSGTPLVSANQGVTG 548
               RP   G      N G TG
Sbjct: 308 GERGRPGAPGPAGARGNDGATG 329



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 16/25 (64%), Positives = 16/25 (64%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPP 80
            RG  G  GP GP GP G PGP GPP
Sbjct: 1168 RGRTGDAGPVGPPGPPGPPGPPGPP 1192


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  446 bits (1148), Expect = e-125
 Identities = 269/577 (46%), Positives = 296/577 (51%), Gaps = 101/577 (17%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPG----PSAVGKPGV 110
            RGEQG PGP G  G  G PGP G  GKPG  G PG  G PGL GP G    P   G PG 
Sbjct: 653  RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 712

Query: 111  PGLPGK---PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGP---AGISVP----GKPGQ 160
             GL G    PG  G  GPKG  GPAG PG +GPPG  G+PG    AGI+ P    G  G+
Sbjct: 713  QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772

Query: 161  QGPTGAPGP---RGFPGEKGAPGVPGMNGQKGEMG-------YGAPGRPGERGLPGPQGP 210
            +GP GAPG    RG  G  G PG  G NG+KGE+G        GA G PGERG  GP GP
Sbjct: 773  KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 211  TGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGA 268
             G +GPPG  G+ G  G  G+ G KGD G PG  GP G PGPQGP G  GP+G  G  G 
Sbjct: 833  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 269  AGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGP 327
             GA G PG  G  G PG+ G  GPPGPPG  GK G  G +G+ GP G  G PG +G  GP
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 328  AGLPGKPGLTGPPGNMGPQGPKGI---------------------------PGSHGLPGP 360
             G  G+PG  GP G  GP GP+G+                           PG  G PG 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 361  KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG------------NPGLPGP 408
             G+ GP GP G PG  G  G PG +G PG  G PG DG  G             PG PGP
Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1072

Query: 409  KGDPGVGGPPGLPG------------PVGPAGAKGMPG------HNGEAGPRGAPGIPGT 450
             G PG  GP G  G            P GPAGA+G+ G        GEAG  G  G+ G 
Sbjct: 1073 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1132

Query: 451  RGPIGPPGIPGFPGSKGDPGSPGP---------PGPAGIATK-GLNGPTGPPGPPGPRGH 500
            RG  G  G+PG PG  GD G+ GP         PGP G + K G NG  GP GPPGPRG 
Sbjct: 1133 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1192

Query: 501  SGE------PGLPGPPGPPGPPGQAVMPEGFIKAGQR 531
            SGE      PG PGPPGPPGPPG  +    F   G R
Sbjct: 1193 SGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR 1229



 Score =  444 bits (1141), Expect = e-124
 Identities = 275/633 (43%), Positives = 320/633 (50%), Gaps = 124/633 (19%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYG 86
            P G  GPL   K Q   P      GIA  +GEQG  G PGPAGP+G PGP+G  GK G  
Sbjct: 442  PQGATGPL-GPKGQTGEP------GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG-- 492

Query: 87   SPGLQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG 145
                +GEPG  GP GP    G PG  G PG+ G  GP G  G+ GP+GL GP+G  G PG
Sbjct: 493  ---ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 549

Query: 146  IPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-------- 193
             PG  G+     + G+PG  GP G  GP G PGE G PG PG  G +G+ G         
Sbjct: 550  RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 609

Query: 194  -----------GAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKGDRG 238
                       G PG PG RGLPG  G TG +GPPG     G+RGE G PG  G +G  G
Sbjct: 610  ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 669

Query: 239  FPGEMGPIGPPGPQGPPGERGPEGI-------GKPGAAGAPGQPGIPGTKGLPGAPGI-- 289
             PG  G  G PG QG PGE G  G+       G PG  G+PG  G+ G +GLPG PG   
Sbjct: 670  PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 729

Query: 290  ----AGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKG---EQGPAGLPGKPG---LTG 338
                +GP GPPG  G PGL G+ GERG AG+ G  G +G   E+GP G PGK G   LTG
Sbjct: 730  PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 789

Query: 339  P------------PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY---PGAKGERGSPG 383
            P             G +GP GP G  G+ G PG +GETGP GPAG+   PGA G+ G+ G
Sbjct: 790  PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 849

Query: 384  SDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGP---------------PGLPGPVGPAG 428
              G+ G  G  G  GP+G  G PGP+G  GV GP               PG  G VGP G
Sbjct: 850  EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 909

Query: 429  AKGMP---------------GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPG 473
            + G P               G  G++GP G  G PG +GP GPPG  G PG  G  G+ G
Sbjct: 910  SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969

Query: 474  PPGPAGIATK----------------GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517
            PPGP G+A +                GL GP+G PG  G  G SG+ G PGP GPPG  G
Sbjct: 970  PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 1029

Query: 518  QAVMP--EGFIKAGQRPSLSGTPLVSANQGVTG 548
             A  P  EG   A   P   G   V  ++G TG
Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 1062



 Score =  437 bits (1123), Expect = e-122
 Identities = 258/573 (45%), Positives = 291/573 (50%), Gaps = 90/573 (15%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGP---PGPSAV------ 105
           RGE GTPG PGPAG  G+PG  G PG  G  G+PG+ G PG PGP   PGP         
Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 451

Query: 106 -GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGP------------------------RGP 140
            G+ G PG+ G  GE+GP G  G  GP G PGP                        RG 
Sbjct: 452 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 511

Query: 141 PGPPGIPGPAGISVP-GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG------- 192
           PG  G PG  G++ P G PG++GP+G  GP+G  G+ G PG PG+ G +G  G       
Sbjct: 512 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 571

Query: 193 ---YGAPGRPGERGLPGPQGPTGPSGPPGV-------------GKRGENGVPGQPGIKGD 236
               G  G PGE G PGP GP G  G PGV             GK GE G+PG PG++G 
Sbjct: 572 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 631

Query: 237 RGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPP 296
            G  GE G  GPPGP GP GERG +G   PG +G  G PG PG  G  G PG  G PG  
Sbjct: 632 PGKDGETGAAGPPGPAGPAGERGEQGA--PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 689

Query: 297 GFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHG 356
           G   PGL G +GERG  G  G PGA+G QGP GLPG PG  GP G  GP GP G  G  G
Sbjct: 690 G--APGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 747

Query: 357 LPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGG 416
           L G  GE G AG AG  G +G+ G  G +G PG  G  GL GP G PG  G  G+ G  G
Sbjct: 748 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 807

Query: 417 PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI---PGFPGSKGDPGSPG 473
           P   PGP G AGA+G PG  GE GP G  G  G  G  G PG     G  G KGD G+PG
Sbjct: 808 P---PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 864

Query: 474 PPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGL------------------PGPPGPPGP 515
           P GP+G    G  GPTG  GP G RG  G PG                   PGPPGPPGP
Sbjct: 865 PQGPSG--APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 922

Query: 516 PGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
            G+   P+G       P  +G P +    G  G
Sbjct: 923 SGKD-GPKGARGDSGPPGRAGEPGLQGPAGPPG 954



 Score =  435 bits (1119), Expect = e-122
 Identities = 261/568 (45%), Positives = 294/568 (51%), Gaps = 59/568 (10%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-G 86
           P G  G   N   Q    +  K+ G  +   QG  GP GP GP   PGP+G PG  G+ G
Sbjct: 169 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP---PGPAGAPGPQGFQG 225

Query: 87  SPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146
           +PG  GEPG+ GP GP   G PG PG PG  GE G  G  G+ GP G  G RG PG PG+
Sbjct: 226 NPGEPGEPGVSGPMGPR--GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 283

Query: 147 PGPAG-ISVPGKPGQQGPTGAPGPR---GFPGEKGAPGVPGMNGQKGEMGYGAP-GRPGE 201
           PG  G    PG  G +G  GAPG +   G PGE G+PG  G  G  GE G   P G  G 
Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 343

Query: 202 RGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPE 261
           RG  G  GP GP GP  VG  G  G PG PG KG+ G  G  GP G  GP+G PG   P 
Sbjct: 344 RGNDGQPGPAGPPGP--VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT--PG 399

Query: 262 GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------------------FGKPG 302
             G  GA+G PG  GIPG KG  GAPGIAG PG PG                    G+PG
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459

Query: 303 LPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---------KGIPG 353
           + G KGE+GP G PG  G +G  GPAG  GK G  G PG +GP GP         +G PG
Sbjct: 460 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 519

Query: 354 SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG 413
             GL GPKG  G  GP+G  G KG  G PG  G+PG PG  GL G  G+ G  G  G  G
Sbjct: 520 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 579

Query: 414 VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP---GFPGSKGDPG 470
             G  G PGP GP GA+G PG  G  GP+GA G PG  G  G PG P   G PG  G+ G
Sbjct: 580 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 639

Query: 471 SPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP-----EGF 525
           + GPPGPAG A     G  G  G PGP G  G PG PGPPG  G PG   +P      G 
Sbjct: 640 AAGPPGPAGPA-----GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 694

Query: 526 I-KAGQR--PSLSGTPLVSANQGVTGMP 550
           +   G+R  P   G+P     QG  G+P
Sbjct: 695 VGPRGERGFPGERGSPGAQGLQGPRGLP 722



 Score =  419 bits (1077), Expect = e-117
 Identities = 271/620 (43%), Positives = 303/620 (48%), Gaps = 142/620 (22%)

Query: 57  GEQGTPGPPGP----AGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
           G +G  G PG      GP+G PGP GP G+ G  G  G +GE G PGP G    G+PG P
Sbjct: 101 GPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD--GEPGTP 158

Query: 112 GLPGKPGERGPYGPKG------------------------DVGPAGLPGPRGPPGPPGIP 147
           G PG PG  GP GP G                          GP G  GPRGPPGP G P
Sbjct: 159 GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 218

Query: 148 GPAGISV-PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPG 206
           GP G    PG+PG+ G +G  GPRG PG    PG PG +G+ G+     PG+ GERG PG
Sbjct: 219 GPQGFQGNPGEPGEPGVSGPMGPRGPPGP---PGKPGDDGEAGK-----PGKAGERGPPG 270

Query: 207 PQGPTGPSGPPGV-GKRGENGVPG---------QPGIKGDRGFPGEMGPIGPPGPQGPPG 256
           PQG  G  G PG+ G +G  G PG          PG+KG+ G PGE G  GP GP+G PG
Sbjct: 271 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 330

Query: 257 ERGPEGI----------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKP----- 301
           ERG  G           G+PG AG PG  G  G  G PGAPG  G  GP G   P     
Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 390

Query: 302 --GLPGLKGERGPAGLPGG------PGAKGEQGPAGLPGKPGLTGPPGNMGPQ------G 347
             G PG  G  GPAG  G       PGAKG  G  G+ G PG  GP G  GPQ      G
Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450

Query: 348 PK------GIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKP------------- 388
           PK      GI G  G  GPKGE GPAGP G PG  GE G  G+ G+P             
Sbjct: 451 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 510

Query: 389 -----GYPGKPGLDGPKGNP------GLPGPK---GDPGVGGPPGLPGPVGPAGAKGMPG 434
                G+PG+ GL GPKG P      GL GPK   GDPG  G PGLPG  G  G  G  G
Sbjct: 511 APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAG 570

Query: 435 HNGEAGPRGAPGIPGTRGPIGP------PGIPGFPGSK---------GDPGSPGPPGPAG 479
             G+ GP GAPG  G  GP GP      PG+ GFPG K         G+ G PG PG  G
Sbjct: 571 PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRG 630

Query: 480 IATK-GLNGPTGPPGPPGPRGHSGEPGLPGP------PGPPGPPGQAVMP--EGFIKAGQ 530
           +  K G  G  GPPGP GP G  GE G PGP      PGPPGPPG+   P  +G      
Sbjct: 631 LPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV----- 685

Query: 531 RPSLSGTPLVSANQGVTGMP 550
            P  +G P +   +G  G P
Sbjct: 686 -PGEAGAPGLVGPRGERGFP 704



 Score =  290 bits (742), Expect = 3e-78
 Identities = 163/350 (46%), Positives = 185/350 (52%), Gaps = 36/350 (10%)

Query: 229 GQPGIKGDRGFPGEM----GPIGPPGPQGPPGERGPEGI----GKPGAAGAPGQPGIPGT 280
           GQPG KG +G PG++    GP GPPGPQGP GE+GP G     G+ GA G  G+ G PGT
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 281 KGLPGAPGIAGPPGPPGFG----------------------KPGLPGLKGERGPAGLPGG 318
            G PG PG  GPPGPPG G                        G  G  G RGP G  G 
Sbjct: 158 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 217

Query: 319 PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
           PG +G QG  G PG+PG++GP G  GP GP G PG  G  G  G+ G  GP G  GA+G 
Sbjct: 218 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 277

Query: 379 RGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGE 438
            G+PG  G  G+ G PGLDG KG  G PG KG+ G  G  G PGP+GP   +G+PG  G 
Sbjct: 278 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP---RGLPGERGR 334

Query: 439 AGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPR 498
            GP GA G  G  G  GP G PG  G  G PG PG PG  G A  G  G  GP G  GPR
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEA--GPTGARGPEGAQGPR 392

Query: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
           G  G PG PGP G  G PG   +P     AG  P ++G P     +G  G
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAG-APGIAGAPGFPGPRGPPG 441



 Score =  155 bits (392), Expect = 1e-37
 Identities = 100/259 (38%), Positives = 114/259 (44%), Gaps = 58/259 (22%)

Query: 339 PPGNMGPQGPKGIPGSHGLPGPKGE-------------TGPAGPAGYPGAKGERGSPGSD 385
           P G   P  P  +  + G PGPKG+              GP GP G  G +G RG  G  
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 386 GKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL------------------------P 421
           G+ G PG  G DG  G PG PGP G PG  GPPGL                         
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 422 GPVGPAGAKGMPGHNGEAGPR------GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPP 475
           GP+GP G +G PG  G  GP+      G PG PG  GP+GP G PG PG  GD G  G P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 476 GPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGP------PGPPGPPGQAVMPEGFIKAG 529
           G A        G  GPPGP G RG  G PGLPG       PG  G  G+A  P G     
Sbjct: 261 GKA--------GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAP-GVKGES 311

Query: 530 QRPSLSGTPLVSANQGVTG 548
             P  +G+P     +G+ G
Sbjct: 312 GSPGENGSPGPMGPRGLPG 330



 Score =  134 bits (338), Expect = 2e-31
 Identities = 92/229 (40%), Positives = 105/229 (45%), Gaps = 51/229 (22%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115
            RGE G  G PG  GP   PG  GP G    G  G +GE G  GP GPS        G  G
Sbjct: 1058 RGETGAVGAPGAPGP---PGSPGPAGPT--GKQGDRGEAGAQGPMGPS--------GPAG 1104

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175
              G +GP GP+GD G AG PG RG  G  G  G  G+  PG PG  G  GA GP G  G 
Sbjct: 1105 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL--PGPPGPSGDQGASGPAGPSGP 1162

Query: 176  KGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKG 235
            +G PG  G +G+      GA G PG  G PGP+G +G +GP G                 
Sbjct: 1163 RGPPGPVGPSGKD-----GANGIPGPIGPPGPRGRSGETGPAGP---------------- 1201

Query: 236  DRGFPGEMGPIGPPGPQGP-----------PGERGPEGIGKPGAAGAPG 273
                PG  GP GPPGP GP           P E+GP+ +    A  A G
Sbjct: 1202 ----PGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1246



 Score =  134 bits (337), Expect = 3e-31
 Identities = 82/181 (45%), Positives = 91/181 (50%), Gaps = 10/181 (5%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
            +   G  G PG PGPAGP G  G  G  G  G  G  G  G  G+ GP GP      G  
Sbjct: 1064 VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR-----GDK 1118

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPR 170
            G  G+PGERG  G +G  G  GLPGP GP G  G  GPAG S P G PG  GP+G  G  
Sbjct: 1119 GEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN 1178

Query: 171  GFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP-TGPSGPPGVGKRGENGVPG 229
            G PG  G PG  G +G+ G    G PG PG  G PGP GP    S   G+G R +   P 
Sbjct: 1179 GIPGPIGPPGPRGRSGETGPA--GPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1236

Query: 230  Q 230
            Q
Sbjct: 1237 Q 1237


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  446 bits (1148), Expect = e-125
 Identities = 269/577 (46%), Positives = 296/577 (51%), Gaps = 101/577 (17%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPG----PSAVGKPGV 110
            RGEQG PGP G  G  G PGP G  GKPG  G PG  G PGL GP G    P   G PG 
Sbjct: 584  RGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGA 643

Query: 111  PGLPGK---PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGP---AGISVP----GKPGQ 160
             GL G    PG  G  GPKG  GPAG PG +GPPG  G+PG    AGI+ P    G  G+
Sbjct: 644  QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703

Query: 161  QGPTGAPGP---RGFPGEKGAPGVPGMNGQKGEMG-------YGAPGRPGERGLPGPQGP 210
            +GP GAPG    RG  G  G PG  G NG+KGE+G        GA G PGERG  GP GP
Sbjct: 704  KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 211  TGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGA 268
             G +GPPG  G+ G  G  G+ G KGD G PG  GP G PGPQGP G  GP+G  G  G 
Sbjct: 764  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 269  AGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGP 327
             GA G PG  G  G PG+ G  GPPGPPG  GK G  G +G+ GP G  G PG +G  GP
Sbjct: 824  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 883

Query: 328  AGLPGKPGLTGPPGNMGPQGPKGI---------------------------PGSHGLPGP 360
             G  G+PG  GP G  GP GP+G+                           PG  G PG 
Sbjct: 884  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943

Query: 361  KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG------------NPGLPGP 408
             G+ GP GP G PG  G  G PG +G PG  G PG DG  G             PG PGP
Sbjct: 944  SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGP 1003

Query: 409  KGDPGVGGPPGLPG------------PVGPAGAKGMPG------HNGEAGPRGAPGIPGT 450
             G PG  GP G  G            P GPAGA+G+ G        GEAG  G  G+ G 
Sbjct: 1004 PGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGH 1063

Query: 451  RGPIGPPGIPGFPGSKGDPGSPGP---------PGPAGIATK-GLNGPTGPPGPPGPRGH 500
            RG  G  G+PG PG  GD G+ GP         PGP G + K G NG  GP GPPGPRG 
Sbjct: 1064 RGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGR 1123

Query: 501  SGE------PGLPGPPGPPGPPGQAVMPEGFIKAGQR 531
            SGE      PG PGPPGPPGPPG  +    F   G R
Sbjct: 1124 SGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPR 1160



 Score =  444 bits (1141), Expect = e-124
 Identities = 275/633 (43%), Positives = 320/633 (50%), Gaps = 124/633 (19%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYG 86
           P G  GPL   K Q   P      GIA  +GEQG  G PGPAGP+G PGP+G  GK G  
Sbjct: 373 PQGATGPL-GPKGQTGEP------GIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG-- 423

Query: 87  SPGLQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG 145
               +GEPG  GP GP    G PG  G PG+ G  GP G  G+ GP+GL GP+G  G PG
Sbjct: 424 ---ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPG 480

Query: 146 IPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-------- 193
            PG  G+     + G+PG  GP G  GP G PGE G PG PG  G +G+ G         
Sbjct: 481 RPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKG 540

Query: 194 -----------GAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKGDRG 238
                      G PG PG RGLPG  G TG +GPPG     G+RGE G PG  G +G  G
Sbjct: 541 ANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPG 600

Query: 239 FPGEMGPIGPPGPQGPPGERGPEGI-------GKPGAAGAPGQPGIPGTKGLPGAPGI-- 289
            PG  G  G PG QG PGE G  G+       G PG  G+PG  G+ G +GLPG PG   
Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDG 660

Query: 290 ----AGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKG---EQGPAGLPGKPG---LTG 338
               +GP GPPG  G PGL G+ GERG AG+ G  G +G   E+GP G PGK G   LTG
Sbjct: 661 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG 720

Query: 339 P------------PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY---PGAKGERGSPG 383
           P             G +GP GP G  G+ G PG +GETGP GPAG+   PGA G+ G+ G
Sbjct: 721 PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKG 780

Query: 384 SDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGP---------------PGLPGPVGPAG 428
             G+ G  G  G  GP+G  G PGP+G  GV GP               PG  G VGP G
Sbjct: 781 EQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG 840

Query: 429 AKGMP---------------GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPG 473
           + G P               G  G++GP G  G PG +GP GPPG  G PG  G  G+ G
Sbjct: 841 SNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900

Query: 474 PPGPAGIATK----------------GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517
           PPGP G+A +                GL GP+G PG  G  G SG+ G PGP GPPG  G
Sbjct: 901 PPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 960

Query: 518 QAVMP--EGFIKAGQRPSLSGTPLVSANQGVTG 548
            A  P  EG   A   P   G   V  ++G TG
Sbjct: 961 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETG 993



 Score =  437 bits (1123), Expect = e-122
 Identities = 258/573 (45%), Positives = 291/573 (50%), Gaps = 90/573 (15%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGP---PGPSAV------ 105
           RGE GTPG PGPAG  G+PG  G PG  G  G+PG+ G PG PGP   PGP         
Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGP 382

Query: 106 -GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGP------------------------RGP 140
            G+ G PG+ G  GE+GP G  G  GP G PGP                        RG 
Sbjct: 383 KGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 141 PGPPGIPGPAGISVP-GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG------- 192
           PG  G PG  G++ P G PG++GP+G  GP+G  G+ G PG PG+ G +G  G       
Sbjct: 443 PGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGP 502

Query: 193 ---YGAPGRPGERGLPGPQGPTGPSGPPGV-------------GKRGENGVPGQPGIKGD 236
               G  G PGE G PGP GP G  G PGV             GK GE G+PG PG++G 
Sbjct: 503 QGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGL 562

Query: 237 RGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPP 296
            G  GE G  GPPGP GP GERG +G   PG +G  G PG PG  G  G PG  G PG  
Sbjct: 563 PGKDGETGAAGPPGPAGPAGERGEQGA--PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEA 620

Query: 297 GFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHG 356
           G   PGL G +GERG  G  G PGA+G QGP GLPG PG  GP G  GP GP G  G  G
Sbjct: 621 G--APGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678

Query: 357 LPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGG 416
           L G  GE G AG AG  G +G+ G  G +G PG  G  GL GP G PG  G  G+ G  G
Sbjct: 679 LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738

Query: 417 PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI---PGFPGSKGDPGSPG 473
           P   PGP G AGA+G PG  GE GP G  G  G  G  G PG     G  G KGD G+PG
Sbjct: 739 P---PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG 795

Query: 474 PPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGL------------------PGPPGPPGP 515
           P GP+G    G  GPTG  GP G RG  G PG                   PGPPGPPGP
Sbjct: 796 PQGPSG--APGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 853

Query: 516 PGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
            G+   P+G       P  +G P +    G  G
Sbjct: 854 SGKD-GPKGARGDSGPPGRAGEPGLQGPAGPPG 885



 Score =  435 bits (1119), Expect = e-122
 Identities = 261/568 (45%), Positives = 294/568 (51%), Gaps = 59/568 (10%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-G 86
           P G  G   N   Q    +  K+ G  +   QG  GP GP GP   PGP+G PG  G+ G
Sbjct: 100 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP---PGPAGAPGPQGFQG 156

Query: 87  SPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146
           +PG  GEPG+ GP GP   G PG PG PG  GE G  G  G+ GP G  G RG PG PG+
Sbjct: 157 NPGEPGEPGVSGPMGPR--GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 214

Query: 147 PGPAG-ISVPGKPGQQGPTGAPGPR---GFPGEKGAPGVPGMNGQKGEMGYGAP-GRPGE 201
           PG  G    PG  G +G  GAPG +   G PGE G+PG  G  G  GE G   P G  G 
Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 274

Query: 202 RGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPE 261
           RG  G  GP GP GP  VG  G  G PG PG KG+ G  G  GP G  GP+G PG   P 
Sbjct: 275 RGNDGQPGPAGPPGP--VGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGT--PG 330

Query: 262 GIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------------------FGKPG 302
             G  GA+G PG  GIPG KG  GAPGIAG PG PG                    G+PG
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390

Query: 303 LPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---------KGIPG 353
           + G KGE+GP G PG  G +G  GPAG  GK G  G PG +GP GP         +G PG
Sbjct: 391 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 450

Query: 354 SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG 413
             GL GPKG  G  GP+G  G KG  G PG  G+PG PG  GL G  G+ G  G  G  G
Sbjct: 451 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 510

Query: 414 VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP---GFPGSKGDPG 470
             G  G PGP GP GA+G PG  G  GP+GA G PG  G  G PG P   G PG  G+ G
Sbjct: 511 APGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETG 570

Query: 471 SPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP-----EGF 525
           + GPPGPAG A     G  G  G PGP G  G PG PGPPG  G PG   +P      G 
Sbjct: 571 AAGPPGPAGPA-----GERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625

Query: 526 I-KAGQR--PSLSGTPLVSANQGVTGMP 550
           +   G+R  P   G+P     QG  G+P
Sbjct: 626 VGPRGERGFPGERGSPGAQGLQGPRGLP 653



 Score =  419 bits (1078), Expect = e-117
 Identities = 274/631 (43%), Positives = 309/631 (48%), Gaps = 144/631 (22%)

Query: 48  IKSKGIAVR--GEQGTPGPPGP----AGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPP 100
           ++ +G  VR  G +G  G PG      GP+G PGP GP G+ G  G  G +GE G PGP 
Sbjct: 21  LRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 80

Query: 101 GPSAVGKPGVPGLPGKPGERGPYGPKG------------------------DVGPAGLPG 136
           G    G+PG PG PG PG  GP GP G                          GP G  G
Sbjct: 81  GRD--GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMG 138

Query: 137 PRGPPGPPGIPGPAGISV-PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGA 195
           PRGPPGP G PGP G    PG+PG+ G +G  GPRG PG    PG PG +G+ G+     
Sbjct: 139 PRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP---PGKPGDDGEAGK----- 190

Query: 196 PGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPG---------QPGIKGDRGFPGEMGP 245
           PG+ GERG PGPQG  G  G PG+ G +G  G PG          PG+KG+ G PGE G 
Sbjct: 191 PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS 250

Query: 246 IGPPGPQGPPGERGPEGI----------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295
            GP GP+G PGERG  G           G+PG AG PG  G  G  G PGAPG  G  GP
Sbjct: 251 PGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP 310

Query: 296 PGFGKP-------GLPGLKGERGPAGLPGG------PGAKGEQGPAGLPGKPGLTGPPGN 342
            G   P       G PG  G  GPAG  G       PGAKG  G  G+ G PG  GP G 
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 343 MGPQ------GPK------GIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKP-- 388
            GPQ      GPK      GI G  G  GPKGE GPAGP G PG  GE G  G+ G+P  
Sbjct: 371 PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGG 430

Query: 389 ----------------GYPGKPGLDGPKGNP------GLPGPK---GDPGVGGPPGLPGP 423
                           G+PG+ GL GPKG P      GL GPK   GDPG  G PGLPG 
Sbjct: 431 VGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490

Query: 424 VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGP------PGIPGFPGSK---------GD 468
            G  G  G  G  G+ GP GAPG  G  GP GP      PG+ GFPG K         G+
Sbjct: 491 RGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGE 550

Query: 469 PGSPGPPGPAGIATK-GLNGPTGPPGPPGPRGHSGEPGLPGP------PGPPGPPGQAVM 521
            G PG PG  G+  K G  G  GPPGP GP G  GE G PGP      PGPPGPPG+   
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610

Query: 522 P--EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           P  +G       P  +G P +   +G  G P
Sbjct: 611 PGDQGV------PGEAGAPGLVGPRGERGFP 635



 Score =  134 bits (338), Expect = 2e-31
 Identities = 92/229 (40%), Positives = 105/229 (45%), Gaps = 51/229 (22%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115
            RGE G  G PG  GP   PG  GP G    G  G +GE G  GP GPS        G  G
Sbjct: 989  RGETGAVGAPGAPGP---PGSPGPAGPT--GKQGDRGEAGAQGPMGPS--------GPAG 1035

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGE 175
              G +GP GP+GD G AG PG RG  G  G  G  G+  PG PG  G  GA GP G  G 
Sbjct: 1036 ARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL--PGPPGPSGDQGASGPAGPSGP 1093

Query: 176  KGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKG 235
            +G PG  G +G+      GA G PG  G PGP+G +G +GP G                 
Sbjct: 1094 RGPPGPVGPSGKD-----GANGIPGPIGPPGPRGRSGETGPAGP---------------- 1132

Query: 236  DRGFPGEMGPIGPPGPQGP-----------PGERGPEGIGKPGAAGAPG 273
                PG  GP GPPGP GP           P E+GP+ +    A  A G
Sbjct: 1133 ----PGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAG 1177



 Score =  134 bits (337), Expect = 3e-31
 Identities = 82/181 (45%), Positives = 91/181 (50%), Gaps = 10/181 (5%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
            +   G  G PG PGPAGP G  G  G  G  G  G  G  G  G+ GP GP      G  
Sbjct: 995  VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPR-----GDK 1049

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPR 170
            G  G+PGERG  G +G  G  GLPGP GP G  G  GPAG S P G PG  GP+G  G  
Sbjct: 1050 GEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGAN 1109

Query: 171  GFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGP-TGPSGPPGVGKRGENGVPG 229
            G PG  G PG  G +G+ G    G PG PG  G PGP GP    S   G+G R +   P 
Sbjct: 1110 GIPGPIGPPGPRGRSGETGPA--GPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1167

Query: 230  Q 230
            Q
Sbjct: 1168 Q 1168


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  446 bits (1146), Expect = e-125
 Identities = 264/596 (44%), Positives = 309/596 (51%), Gaps = 102/596 (17%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG------PSGPPG 81
           P G  G LP T T  F P+         +GE+G PG PG  G +G PG      P+GPPG
Sbjct: 326 PAGPPG-LPGT-TSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 383

Query: 82  KPG----YGSPGLQGEPGLPG---PPGPS----AVGKPGVPGLPGKPGERGPYGPKGDVG 130
             G    +G+PG  G PG PG    PGPS    +VG PG+ G PGK GERG  G  G+ G
Sbjct: 384 AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 443

Query: 131 PAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGE 190
             G  GPRG PG PG+PGP G    G+PG +G  G PGP G  G++GAPG+PG  G +G+
Sbjct: 444 SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGD 503

Query: 191 MGYGAPG------------RPGERGLPG---PQGPTG----------------------- 212
            G G  G             PG RGLPG   PQGP G                       
Sbjct: 504 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCND 563

Query: 213 -PSGPPGV----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP------QGPPGERGPE 261
            P GPPG+    G +G+ GVPG+PG +G  G  GE GP G PGP      QG  GERG +
Sbjct: 564 CPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGAD 623

Query: 262 G-IGKPGAAGAPGQPGI---PGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLP 316
           G +G+ G  G PG PG    PG  G PGA GIAG  GPPG  G PG  G  G +GP+GLP
Sbjct: 624 GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLP 683

Query: 317 GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAK 376
           G PG +G++G  G PG      PPG  G  G  G+PG  G  GP G  G  G +G PG +
Sbjct: 684 GIPGEEGKEGRDGKPG------PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPR 737

Query: 377 GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN 436
           GE G+ G  G+ G PGK G  GP G  G  GP+G PG  G PG PG  GP+G  G  G  
Sbjct: 738 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK 797

Query: 437 GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPG 496
           GE G  G PG  G RGP G PG  G PG +G PG PG PG  G   +G  G  G  GPPG
Sbjct: 798 GENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG--ERGDPGIKGDKGPPG 855

Query: 497 PRGHSGEPGLP------------------GPPGPPGPPGQAVMPEGFIKAGQRPSL 534
            +G  G+PG+P                  GP GPPGPPGQ   P      G+ PS+
Sbjct: 856 GKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG---LRGESPSM 908



 Score =  439 bits (1130), Expect = e-123
 Identities = 270/622 (43%), Positives = 305/622 (49%), Gaps = 139/622 (22%)

Query: 51   KGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGV 110
            KG A  GE+G+PGP GP G  G PG  GPPGK   G PGL+G PGLPGP G    G  G 
Sbjct: 436  KGAA--GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTK--GDRGA 491

Query: 111  PGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPR 170
            PG+PG PG RG  G    +G AG PGP GPPG  G PG  G+  PG PG QGP G  G  
Sbjct: 492  PGIPGSPGSRGDPG----IGVAGPPGPSGPPGDKGSPGSRGL--PGFPGPQGPAGRDGLS 545

Query: 171  GF--PGE-------------KGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPS 214
                PG+              G PG+PG+ G KG+ G  G PGR G  G  G  GP G  
Sbjct: 546  SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 605

Query: 215  GPPGV----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGE------RGPEGI- 263
            GPPG+    G +GE G  G+ G KGD+G PG  G +GPPG  GPPG        GP GI 
Sbjct: 606  GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQ 665

Query: 264  ------GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLP 316
                  G PG  G  G PGIPG +G  G  G  GPPG PG  G+PGLPG +G RGP G  
Sbjct: 666  GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725

Query: 317  G------GPGAKGEQGPAGLPGKPGL------TGPPGNMGPQGPKGIPGSHGLPGPKGET 364
            G       PG +GE G  GLPG+ GL      TGP G  GPQGP+G PG +G PG  GE 
Sbjct: 726  GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP 785

Query: 365  GPAGPAGYPGAKGERGSPG------------SDGKPGYPGKPGLDGPKGNPGLPGPKGDP 412
            GP+G  G  G+KGE GSPG              G+ G PGK G+ G  G PG  G +GDP
Sbjct: 786  GPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP 845

Query: 413  GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPG-------- 464
            G+ G  G PG  G  G  G+PGH G  G  G  G+PG  GP+GPPG PG PG        
Sbjct: 846  GIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGES 905

Query: 465  ------------------------------------SKGDPGSPGPPGPAGIATKGLNGP 488
                                                S+G PG PGPPG  G+   G  GP
Sbjct: 906  PSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP--GRAGP 963

Query: 489  TGPP---------------GPPGPRGHSGEPGLP-----GPPGPPGPPGQAVMPEGFIKA 528
             G P               GP G RG  G+PG P     G  GPPG PGQ   P G+ K 
Sbjct: 964  MGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEP-GYAKD 1022

Query: 529  GQRPSLSGTPLVSANQGVTGMP 550
            G    L G P      G  G P
Sbjct: 1023 G----LPGIPGPQGETGPAGHP 1040



 Score =  409 bits (1051), Expect = e-114
 Identities = 248/586 (42%), Positives = 287/586 (48%), Gaps = 98/586 (16%)

Query: 56  RGEQGTPGPP---------GPAGPRGHPGPSGPPGKPGY----------------GSPGL 90
           RGE G PG P         G AG  G  G +G PG PG+                G PGL
Sbjct: 255 RGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 314

Query: 91  QGEPGLPGPPGPSAVGKPGVPGL-------PGKPGERGPYGPKGDVGPAGLP-------- 135
           +G+ G  G  GP+  G PG+PG        P  PGE+GP G KGD G  G P        
Sbjct: 315 KGDRGEKGEAGPA--GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 372

Query: 136 -GPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGE 190
            GP+GP GPPG  G  G        G PG  G  GAPGP G PG  GAPG+ G  G+ GE
Sbjct: 373 LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 432

Query: 191 MGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEM---GPIG 247
              G  G  GE G PGP GP G  G PG+      G  G+PG++G  G PG +   G  G
Sbjct: 433 R--GEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRG 490

Query: 248 PPGPQGPPGERGPEGI---GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF------ 298
            PG  G PG RG  GI   G PG +G PG  G PG++GLPG PG  GP G  G       
Sbjct: 491 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP 550

Query: 299 ----------------GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGN 342
                           G PGLPGL G +G  G+PG PG +G +G  G  G PGL GPPG 
Sbjct: 551 GDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGI 610

Query: 343 MGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGN 402
            GPQG +G  G+ G  G KG+ G  G  G+ G  G  G PG+DG  G  G PG+ G  G 
Sbjct: 611 AGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGK 670

Query: 403 PGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGF 462
            G PGP+G  G+   PG+PG  G  G  G PG  GE G  G PG+PG  G  GPPG  G 
Sbjct: 671 EGPPGPQGPSGL---PGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 727

Query: 463 ------PGSKGDPGSPGPPGPAGIATK-GLNGPTGPPGPPGPR---GHSGEPGLPGPPGP 512
                 PG +G+ G+ G PG  G+  K G  GPTGP GP GPR   G +G PG PG PGP
Sbjct: 728 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 787

Query: 513 PGPPGQAVMP--------EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G PGQ             GF+     P   G   V   +GV G P
Sbjct: 788 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKP 833



 Score =  389 bits (1000), Expect = e-108
 Identities = 246/596 (41%), Positives = 281/596 (47%), Gaps = 162/596 (27%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPG-----PSGPPGKPG-YGSPGLQGEPGLPGPPGPSA-- 104
            +  +G++G PG PG  G RG PG     P GP G PG  GSPG +G PG PGP GP+   
Sbjct: 483  LGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 542

Query: 105  -----------------------VGKPGVPGLPG---------KPGERGPYGPKGDVGPA 132
                                    G PG+PGLPG         KPG  G  G KG+ GP 
Sbjct: 543  GLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPP 602

Query: 133  GLPGP---------------------------------RGPPGPPGIPGPAGIS-VPGKP 158
            GLPGP                                  GPPG PG PG  GI+   G P
Sbjct: 603  GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 662

Query: 159  GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPGPQGPTGP- 213
            G QG  G  GP G  G  G PG+PG  G++G  G     G PG+ GE GLPGP+G  GP 
Sbjct: 663  GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 722

Query: 214  --------SGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI- 263
                    SG PG  G+ G  G+PGQ G+ G  G  G  GP GP GP+GPPG+ G  G  
Sbjct: 723  GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 782

Query: 264  GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-------GKPGLPGLKGERGPAGLP 316
            G+PG +G PGQ G  G  G PG PG  GP GPPG        GK G+PG  GE G  G  
Sbjct: 783  GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGER 842

Query: 317  GGPGAKGEQGPAG---LPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYP 373
            G PG KG++GP G    PG PG+ G  G+ G  GP+G+PG +G   P G  GP G  G+P
Sbjct: 843  GDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENG---PVGPPGPPGQPGFP 899

Query: 374  GAKGE-----------------------------------RGSPGSDGKPGYPGKPGLDG 398
            G +GE                                   + S G  G PG PGK GL  
Sbjct: 900  GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGL-- 957

Query: 399  PKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPG 458
                PG  GP G+PG  G  GL GP GP G K   G  G  G  GAPG+ G RG +GPPG
Sbjct: 958  ----PGRAGPMGEPGRPGQGGLEGPSGPIGPK---GERGAKGDPGAPGV-GLRGEMGPPG 1009

Query: 459  IPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPG 514
            I            PG PG  G A  GL G  GP G  GP GH   PGLPGPPGPPG
Sbjct: 1010 I------------PGQPGEPGYAKDGLPGIPGPQGETGPAGH---PGLPGPPGPPG 1050



 Score =  365 bits (937), Expect = e-101
 Identities = 229/531 (43%), Positives = 263/531 (49%), Gaps = 94/531 (17%)

Query: 103 SAVGKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRGP---PGPPGIPGPAG-- 151
           +A G   + G PG+      PG+ G  G  G+ G AG PG +G    PG PG PG  G  
Sbjct: 241 TAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEK 300

Query: 152 --------ISVPGKPGQQGPTGAPGPRGFPGEKGA-------PGVPGMNGQKGEMG-YGA 195
                   + +PG  G +G  G  GP G PG  G        P +PG  G KGE G  G 
Sbjct: 301 GDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGL 360

Query: 196 PGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGP 254
           PG PG +G PG  GP GP+GPPG  G+ G +G PG  G  G  G  G  GP GPPG  G 
Sbjct: 361 PGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA 420

Query: 255 PGERGPEG----IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGER 310
           PG RG  G     G+ GAAG  G PG  G +G PGAPG+   PGPPG GK G PGL   R
Sbjct: 421 PGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL---PGPPGKGKDGEPGL---R 474

Query: 311 GPAGLPGGPGAKGEQGPAGLPGKP--------GLTGPPGNMGPQGPKGIPGSHGLPGPKG 362
           G  GLPG  G KG++G  G+PG P        G+ GPPG  GP G KG PGS GLPG  G
Sbjct: 475 GSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG 534

Query: 363 ETGPAGPAGY---------------------PGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
             GPAG  G                      PG  G  G PG  G  G PGKPG +G +G
Sbjct: 535 PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG 594

Query: 402 NPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPG 461
             G  GP   PG+ GPPG+ GP G  G +G  G  G+ G +G PG+PG  GP G PG PG
Sbjct: 595 KKGEAGP---PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 651

Query: 462 F---------PGSKGDPGSPGPPGPAGIA-------TKGLNGPTGPPGPPGPRGHSGEPG 505
                     PG +G PG  GPPGP G +        +G  G  G PGPPG  G +GEPG
Sbjct: 652 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711

Query: 506 LPGPPGPPGPPG--------QAVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
           LPGP G  GPPG         A  P G   A   P   G P    + G TG
Sbjct: 712 LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 762



 Score =  281 bits (718), Expect = 2e-75
 Identities = 172/408 (42%), Positives = 199/408 (48%), Gaps = 83/408 (20%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------GSPGLQGEPGLPGP-------- 99
            ++G  G  GPPGP GP G PG  G  GK G        G PG  GEPGLPGP        
Sbjct: 664  IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 723

Query: 100  ----------PGP----SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG 145
                      PGP     A+G PG  GLPGK G+ GP GP+G  GP G PG  G PG PG
Sbjct: 724  FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 783

Query: 146  IPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGL 204
             PGP+G   PG+ G +G  G+PG  GF G +G PG PG  G  G+ G  G PG PG +G 
Sbjct: 784  EPGPSG--TPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 841

Query: 205  PGPQGPTGPSGPPG-VGKRGENGVPGQPG---IKGDRGFPGEMGPIGPPGPQGPPGERGP 260
             G  G  G  GPPG  G+ G+ G+PG  G   + G +G PGE GP+GPPGP G PG  G 
Sbjct: 842  RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 901

Query: 261  EG---------------IGKP------------------GAAGAPGQPGIPGTKGLPGAP 287
             G               +GK                    + G PG PG PG  GLPG  
Sbjct: 902  RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 961

Query: 288  GIAGPPGPPGFG----KPGLPGLKGERGPAGLPGGPGA--KGEQGPAGLPGKPG------ 335
            G  G PG PG G      G  G KGERG  G PG PG   +GE GP G+PG+PG      
Sbjct: 962  GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1021

Query: 336  --LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381
              L G PG  G  GP G PG  G PGP G+  P+  A +       G+
Sbjct: 1022 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGN 1069



 Score =  228 bits (581), Expect = 1e-59
 Identities = 144/329 (43%), Positives = 160/329 (48%), Gaps = 46/329 (13%)

Query: 250 GPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGE 309
           G QGP  +R         AA        PG K L G PG  G  G      PG PGL+GE
Sbjct: 220 GTQGPADQRADARASCILAAKTA-----PGLKQLNGEPGERGEDG-----LPGKPGLRGE 269

Query: 310 RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGP 369
            G  GL G PG KGE G  G PG PG+ G  G+ G +G  G+PG  G  G KGE GPAGP
Sbjct: 270 IGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP 329

Query: 370 AGYPGA----------------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD-- 411
            G PG                 KGE+G PG  G+PG  G+PG  GP+G  G PG KG   
Sbjct: 330 PGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEG 389

Query: 412 ----PGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTR---GPIGPPGIPGFPG 464
               PG  G PG PG VG  G  G PG  G  G RG PG  G R   G  G  G PG  G
Sbjct: 390 AHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVG 449

Query: 465 SKGDPGSPGPPGPAG---IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVM 521
            +GDPG+PG PGP G       GL G  G PGP G +G  G PG+PG PG  G PG  V 
Sbjct: 450 PRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGV- 508

Query: 522 PEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
                 AG  P  SG P    + G  G+P
Sbjct: 509 ------AGP-PGPSGPPGDKGSPGSRGLP 530



 Score =  138 bits (347), Expect = 2e-32
 Identities = 98/261 (37%), Positives = 119/261 (45%), Gaps = 31/261 (11%)

Query: 319 PGAKGEQGPAGLPGKPGLTGPPGNMGPQG--PKG----IPGSHGLPGPKGETGPAGPAGY 372
           P    +QG  G  G+   +  P ++ PQ   PKG       + G  GP  +   A  +  
Sbjct: 177 PWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCI 236

Query: 373 PGAKGERGSPGSDGKPGYP------GKPGLDGPKGNPGL---PGPKGDPGVGGPPGLP-- 421
             AK   G    +G+PG        GKPGL G  G  GL   PG KG+ G+ G PG P  
Sbjct: 237 LAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGV 296

Query: 422 ----------GPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGP-PGIPGFPGSKGDPG 470
                     G +G  G KG  G  GEAGP G PG+PGT     P P +PG  G KG+ G
Sbjct: 297 RGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKG 356

Query: 471 SPGPPGPAGIATK-GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ--AVMPEGFIK 527
            PG PG  G+  + G  GP GP GPPG +G  G  G PG  G PG PG   A  P G   
Sbjct: 357 DPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 416

Query: 528 AGQRPSLSGTPLVSANQGVTG 548
           +   P L GTP     +G  G
Sbjct: 417 SVGAPGLRGTPGKDGERGEKG 437



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 51/112 (45%), Positives = 62/112 (55%), Gaps = 14/112 (12%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116
            G+ G  GP GP GP+G  G  G PG PG G  G  G PG+PG PG     K G+PG+P  
Sbjct: 971  GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP-- 1028

Query: 117  PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG----ISVPGKPGQ-QGP 163
                   GP+G+ GPAG PG  GPPGPPG   P+      S+  +PG  +GP
Sbjct: 1029 -------GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1073


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  442 bits (1137), Expect = e-124
 Identities = 281/671 (41%), Positives = 314/671 (46%), Gaps = 145/671 (21%)

Query: 20   FYAERYQMPTGIKGP--LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG-- 75
            F  E+   P G  GP   P    Q  IP       +   G++G  G PG  GPRG PG  
Sbjct: 732  FGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCP 791

Query: 76   -PSGPPGKPGY-------GSPGLQGEPGLPGPPG-------PSAVGKPGVPGLPGKPGER 120
               GP G PG+       G  G  G PG+PGPPG       P   G+PG+PG PG PG  
Sbjct: 792  GAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAP 851

Query: 121  GPYGPKGDVGPAG------------LPGPRGPPGPPGIPGPAGIS-VPGKPGQQGPTGAP 167
            G  G  GDVGP G             PG  GPPG PGIPGP G   +PG PG +GP G P
Sbjct: 852  GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLP 911

Query: 168  GPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSG----------- 215
            G  GFPGE+G PG  G  G KGE G  G  G PG+RGL G +G  GP G           
Sbjct: 912  GFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQK 971

Query: 216  -------PPG----VGKRGENGVPGQPGIKGD----------RGFPGEMGPIGPPGPQGP 254
                   PPG     G+RG+ G PG  G +G+          RG PGE G  GPPGP GP
Sbjct: 972  GTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGP 1031

Query: 255  PGERGPEGI----GKPGAAGAPGQPGIPGTKGLPGA----------------PGIAGPPG 294
            PG  G  G     G PG  G PG PG PG  G+ GA                PG  G PG
Sbjct: 1032 PGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPG 1091

Query: 295  PPGF-------GKPGLPGLKGERGPAGLPGGPGAKG---------------------EQG 326
             PG        G+ GLPG++G RG  G PG PG+ G                     + G
Sbjct: 1092 SPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPG 1151

Query: 327  PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG--------ETGPAGPAGYPGAKGE 378
            P GL G PG+ GPPG  GP G  G+ G HGL G KG        + GP GP G PG KGE
Sbjct: 1152 PRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGE 1211

Query: 379  RGSPGSDG--KPGYPGKPGLDGPKGNPGLPGPKG----------DPGVGGPPGLPGPVGP 426
            RG PGS G   PG  GK G  GP G+ G PGP G          DPG  G  G PGP GP
Sbjct: 1212 RGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGP 1271

Query: 427  AGAKGMPGH-------NGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG 479
             GA G PG         GE G  G PG PG  GP GPPG  GFPG  G  G  GP G   
Sbjct: 1272 RGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVG--- 1328

Query: 480  IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPL 539
                G  GP G PGPPG +G  G PG  GP G PGP G+   P       + P L G P 
Sbjct: 1329 --FPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPG 1386

Query: 540  VSANQGVTGMP 550
            +   +G  G+P
Sbjct: 1387 MRGPEGAMGLP 1397



 Score =  418 bits (1074), Expect = e-116
 Identities = 272/658 (41%), Positives = 307/658 (46%), Gaps = 166/658 (25%)

Query: 57   GEQGTPGPPGPAGPRGHPG-PSGPPGKPGY-GSPGLQGEPGLPGPPGPS----AVGKPGV 110
            G QG PG PG  G  G PG P   PGKPG  GSPGL G PGL G PG S    +VG PG 
Sbjct: 408  GPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGP 467

Query: 111  PGLPGKPGERGPYGPKGDVGPAGL----PGPRGPPGPPGIPGPAG----ISVPG---KPG 159
             G+ GK G  G  GPKG+ G  GL    PGP GPPGPPG+PG  G    + +PG     G
Sbjct: 468  QGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKG 527

Query: 160  QQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEM------------------GY-------- 193
              GP GA GP G PG+ GA G PG  G KG+M                  G+        
Sbjct: 528  DPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHG 587

Query: 194  --------GAPGRPGE--------RGLPGPQGP---TGPSGPPGVG------KRGENGVP 228
                    G PG PG+        +G PGP GP    GP GPPG+G      +RG  GVP
Sbjct: 588  RDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVP 647

Query: 229  GQPGIKGDRGFPGEMGP-----IGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKG 282
            G PG++G  G  G+ G      +  PG  GPPG  GP G  G PG  GAPG  G  G KG
Sbjct: 648  GHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKG 707

Query: 283  LPGAPGIAGPPGPPGF---------------------GKPGLPGLKGERGPAGLP----- 316
             PG PG A  PGPPGF                     G PG PG+ G++G  G P     
Sbjct: 708  RPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHL 767

Query: 317  ------------------GGPGAKGEQGPAGLP---------------GKPGLTGPPGNM 343
                              G PG  G +GPAG+P               G PG+ GPPG+ 
Sbjct: 768  GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHS 827

Query: 344  GPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP 403
              +G  GIPG  GLPG  G  G  G  G PG  G  G  G  G PG PG+PG  GP G P
Sbjct: 828  CERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLP 887

Query: 404  GLPGPKGDPGVGGP------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTR 451
            G+PGP GD G+ GP            PG PG  G  GA+G PG  GE G +G  G+PG R
Sbjct: 888  GIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDR 947

Query: 452  ------GPIGPPGIPG---FPGSKGDPGSPGPPGPAGI-------ATKGLNGPTGPPGPP 495
                  G IGPPG  G       KG PG PGPPG  G         T G+ G  G PG  
Sbjct: 948  GLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY 1007

Query: 496  GP----RGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
            GP    RG  GE G PGPPGPPGPPG   +  GFI     P   G P      G +G+
Sbjct: 1008 GPPGFHRGEPGEKGQPGPPGPPGPPGSTGL-RGFIGFPGLPGDQGEPGSPGPPGFSGI 1064



 Score =  417 bits (1071), Expect = e-116
 Identities = 263/594 (44%), Positives = 297/594 (50%), Gaps = 87/594 (14%)

Query: 57   GEQGTPGPPGPAGPRGHPG--------PSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKP 108
            G    PGPPG  G  G PG        P GPPG PG  SPG+ G+ G+PG P    +G P
Sbjct: 713  GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPG--SPGVNGQKGIPGDPAFGHLGPP 770

Query: 109  GVPGLPGKPGERGPYGPKG---DVGPAGLPGPRGPPGP---------PGIPGPAGISV-- 154
            G  GL G PG +GP G  G     GPAG+PG  G  GP         PG+PGP G S   
Sbjct: 771  GKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCER 830

Query: 155  --------PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG----YGAPGRPG-- 200
                    PG PG  G  GAPG +G PG+ G PG  GM G  G  G    +G PG PG  
Sbjct: 831  GAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIP 890

Query: 201  ----ERGLPGPQGPTGPSGPPGV-------GKRGENGVPG---QPGIKGDRGFPGEMGPI 246
                + GLPGP GP GP G PG        GK G  G PG   +PG KG  G PG+ G  
Sbjct: 891  GPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLR 950

Query: 247  GPPGPQGPPGERGPEGI----GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKP 301
            G  G  GPPG+ G   I    G PG  G PG  G PG +G  G PG+ G  G PG +G P
Sbjct: 951  GAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPP 1010

Query: 302  GL----PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL 357
            G     PG KG+ GP G PG PG+ G +G  G PG PG  G PG+ GP G  GI G+ G 
Sbjct: 1011 GFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGP 1070

Query: 358  PGPKGETGPAGPAGYPGAKGERGSPGSD---GKPGYPGKPGLDGPKGNPGLPGPKGDPGV 414
             G KG+  PA   G PG KGE GSPG     G  G  G PG+ GP+G+PG PGP   PG 
Sbjct: 1071 KGNKGD--PASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP---PGS 1125

Query: 415  GGPPGLPGPVGPAGAKGMPGHNGEAGPR------GAPGIPGTRGPIGPPGIPGFPGSKGD 468
             GPPG PG  G  G +G PG  G+ GPR      G PG PG +GP G PG+ G  G KG 
Sbjct: 1126 SGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQ 1185

Query: 469  PGSP--------GPPGPAGI-ATKGLNGPTGPPG--PPGPRGHSGEPGLPGPPGPPGPPG 517
             G+         GPPGP GI   KG  G  G PG  PPGPRG  G PG PG  GPPGP G
Sbjct: 1186 KGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAG 1245

Query: 518  QAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPA-IGTPIP 570
                    I     P   G P     +G  G P    +V L +  P   G P P
Sbjct: 1246 ATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGP 1299



 Score =  415 bits (1066), Expect = e-116
 Identities = 274/685 (40%), Positives = 315/685 (45%), Gaps = 195/685 (28%)

Query: 30   GIKGP-----LPNTKTQFFIPYTIKSKGIAVR----GEQGTPGPPGPAGPRGHPGPSGPP 80
            GIKGP      P  +    IP  +  KG   R    G  G PGPPG +  RG PG  G P
Sbjct: 780  GIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQP 839

Query: 81   GKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAG--- 133
            G PGY    G+PG +G+PG  GPPGP+  G  G+PGLPG+PG  GP G  G  GP G   
Sbjct: 840  GLPGYPGSPGAPGGKGQPGDVGPPGPA--GMKGLPGLPGRPGAHGPPGLPGIPGPFGDDG 897

Query: 134  LPGPRGPPGPPGIPGPAGI-------------SVPGKPGQQGPTGAPGPRG--------- 171
            LPGP GP GP G+PG  G                 G+PG++G +G PG RG         
Sbjct: 898  LPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIG 957

Query: 172  ---------------------------FPGEKGAPGVPGMNGQKGEMG-YGAPG----RP 199
                                       FPGE+G  G PGM G++GE G YG PG     P
Sbjct: 958  PPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEP 1017

Query: 200  GERGLPGPQGPTGPSG------------------------PPGV---------------- 219
            GE+G PGP GP GP G                        PPG                 
Sbjct: 1018 GEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDP 1077

Query: 220  -------GKRGENGVPGQPG---IKGDRGFPGEMGPIGPPGPQGPPGERGPEGI------ 263
                   G +GE G PG PG     G++G PG  GP G PG  GPPG  GP G       
Sbjct: 1078 ASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGM 1137

Query: 264  ----GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF--------------------- 298
                G+PG  G PG  G+ G  G+PG PGI GP G PG                      
Sbjct: 1138 PGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDV 1197

Query: 299  ---GKPGLPGLKGERGPAGLPG--------------GPGAKGEQGPAGL----------P 331
               G  G+PGLKGERG  G PG               PG+ G  GPAG           P
Sbjct: 1198 GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDP 1257

Query: 332  GKPGLTGPPGNMGPQG---PKGIPGS----HGLPGPKGETGPAGPAGYPGAKGERGSPGS 384
            G PG  GPPG  GP+G   P G+PGS     G PG  G  GP GP G PG  G +G PG 
Sbjct: 1258 GPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGC 1317

Query: 385  DGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG--PR 442
            DGK G  G  G  GP+G  G PGP G+ G+ GPPG  GP G  G +G PG   +    PR
Sbjct: 1318 DGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPR 1377

Query: 443  --GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGH 500
              G PG PG RGP G  G+PG  G  G PG  G PG  G   +G++G  G PGPPG +G 
Sbjct: 1378 IPGLPGAPGMRGPEGAMGLPGMRGPSG-PGCKGEPGLDG--RRGVDGVPGSPGPPGRKGD 1434

Query: 501  SGEPGLPGPPGPPGPPGQAVMPEGF 525
            +GE G PG PGPPGP G    P+GF
Sbjct: 1435 TGEDGYPGGPGPPGPIGDP-GPKGF 1458



 Score =  396 bits (1018), Expect = e-110
 Identities = 269/661 (40%), Positives = 306/661 (46%), Gaps = 173/661 (26%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPG------PPGP------ 102
           +G  G PG PG  G  GHPGP GP GKPG  G  G +G+PG PG      P GP      
Sbjct: 109 KGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGE 168

Query: 103 -----------SAV-------GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPP 144
                       AV       G PG+PGLPG  G  GP GP G  G  GL GP G PG P
Sbjct: 169 KGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRP 228

Query: 145 GIPGPAGISVPGK---PGQQGPTGAPGPR---------GFPGEKGAPGVPGM------NG 186
           G+ G  G+ V G+   PG+ G  G+PGP           + GEKG  G+PGM       G
Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288

Query: 187 QKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGI------------ 233
           +KGE G GA G  G  G PGP+G  G  G PG  G +GE G+ G PG+            
Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGN 348

Query: 234 --------------------KGDRGFP---GEMGPIGPPGPQ--------------GPPG 256
                                GD GFP   GE G +GPPGP               GPPG
Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPG 408

Query: 257 ERGPEGI-GKPGAAG-------APGQPGIPGTKGLPGAPGI------------AGPPGPP 296
            +G  G+ G PG AG       APG+PG PG+ GLPGAPG+             G PGP 
Sbjct: 409 PQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQ 468

Query: 297 GF----GKPGLPGLKGER-------------GPAGLPGGPGAKGEQGPAGLPGKPGLTGP 339
           G     G PG  G KGE+             GP G PG PG +G +G  GLPG  G  G 
Sbjct: 469 GIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGD 528

Query: 340 PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD-- 397
           PG  G +GP G+PG HG  GP G  G  G       KG +G  G DG PG+PG+PG    
Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588

Query: 398 ----GPKGNPG--------LPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 445
               G KG+PG         PG KG PG  GPPG  GPVGP G  G PG  GE G  G P
Sbjct: 589 DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGL-GFPGPPGERGHPGVP 647

Query: 446 GIPGTRGPIGPPGIPG--------FPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGP 497
           G PG RGP G  G  G        +PG  G PG  GPPGP     KG  GP G PG  G 
Sbjct: 648 GHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGP-----KGFPGPQGAPGLSGS 702

Query: 498 RGHSGEPGLPGP---PGPPGPPGQAVMP-----EGFIKAGQRPSLSGTPLVSANQGVTGM 549
            GH G PG PG    PGPPG  G    P     +G    G  P   G+P V+  +G+ G 
Sbjct: 703 DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGP-PGPPGSPGVNGQKGIPGD 761

Query: 550 P 550
           P
Sbjct: 762 P 762



 Score =  393 bits (1009), Expect = e-109
 Identities = 260/620 (41%), Positives = 301/620 (48%), Gaps = 138/620 (22%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG-PSAVGKPGVPGLP 114
           +GE+G  G PG  G    PGP G  G+ G G+ G +G PG PGP G P + G PG PGL 
Sbjct: 269 KGEKGIKGIPGMVGL---PGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLK 325

Query: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI--------PGPAGISVPGKPGQQGPTGA 166
           G+ G  G  G  G +GP G PG RG PGPPG+         GP G   PG PG+ G TG 
Sbjct: 326 GELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPG--DPGFPGRYGETGD 383

Query: 167 PGPRGFPGEKGAPG--VPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPGVGKRG 223
            GP G PG  G PG    GM G  G  G+ G PG PGE G+PG   P    G P  GK G
Sbjct: 384 VGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPG--RPDSAPGKP--GKPG 439

Query: 224 ENGVPGQPGIK------------GDRGFPGEMGPIGPPGPQGPPGERGPEGI--GKPGAA 269
             G+PG PG++            G+ G  G  G +GPPG +GP GE+G EG+   +PG  
Sbjct: 440 SPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPM 499

Query: 270 GAPGQPGIPGTK------GLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAG-------- 314
           G PG PG+PG +      GLPG  G  G PGPPG  G PGLPG  G  GP G        
Sbjct: 500 GPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDM 559

Query: 315 ----LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSH--------GLPGPKG 362
               + G  G +G  GP G PG+PG  G  G+ G +G  G PG H        G PGP G
Sbjct: 560 VVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLG 619

Query: 363 ETGPAGPA-----GYPGAKGERGSPGSDGKPG--------------------YPGK---P 394
             G AGP      G+PG  GERG PG  G PG                    YPG+   P
Sbjct: 620 PPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPP 679

Query: 395 GLDGPKGNPGLPGPKGDPGVGGPPG------------LPGPVGPAGAKGMPGHNGE---- 438
           G DGP G  G PGP+G PG+ G  G            +PGP G  G  G PG  GE    
Sbjct: 680 GFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSS 739

Query: 439 -AGPRGAPGIPGTRGP-----------IGPP------GIPGFPGSKGDPGSPGPPGPAGI 480
             GP G PG PG  G            +GPP      G+PG  G +GDPG PG  GPAGI
Sbjct: 740 PVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGI 799

Query: 481 -------ATKGLNGPTGPPGPPGPRGHS---GEPGLPGPPGPPGPPGQAVMPEGFIKAGQ 530
                    KG  G  G PG PGP GHS   G PG+PG PG PG PG    P G    GQ
Sbjct: 800 PGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGG---KGQ 856

Query: 531 RPSLSGTPLVSANQGVTGMP 550
            P   G P  +  +G+ G+P
Sbjct: 857 -PGDVGPPGPAGMKGLPGLP 875



 Score =  355 bits (912), Expect = 6e-98
 Identities = 257/626 (41%), Positives = 288/626 (46%), Gaps = 147/626 (23%)

Query: 89  GLQGEPGLPGPPGP-SAVGKPGVPGLPGKPGERGPYGP------KGDVGPAGLPGPRGPP 141
           G +G PG PGP GP   +G PG  GL G+ G RG  GP      KGD GP G+PG  G  
Sbjct: 62  GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGLD 121

Query: 142 GPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA--PGVP-GMNGQKGEMGY----- 193
           G PG PGP G    GKPG  G  G+ G  GFPG +GA  PG P G  G+KGE G      
Sbjct: 122 GIPGHPGPPG--PRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFIL 179

Query: 194 -------------GAPGRPGERGLPGPQGPTGPSGPPGV----GKRGENGVPGQP--GIK 234
                        G PG PG  G  GP GPTG  G PG+    G+ G  G+ G P  G+K
Sbjct: 180 GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVK 239

Query: 235 GDRGFPGEMGPIGPPGPQ---GPP------GERGPEGI----GKPGAAGAPGQPGIPGTK 281
           G  G PGE+G  G PGP     PP      GE+G +GI    G PG  G  G+ GI G K
Sbjct: 240 GQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGI-GAK 298

Query: 282 GLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLP---------GGPGAKGEQGPAGL- 330
           G  G PG  GP G PG +G PG PGLKGE G  G P         G PG +G  GP G+ 
Sbjct: 299 GEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVL 358

Query: 331 ----------PGKPGLTGPPGNMGPQGPKGIPGSHGLPGP--KGETGPAGPAGY---PGA 375
                     PG PG  G  G  G  GP G PG  G PG    G  GP GP G+   PG 
Sbjct: 359 VTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGL 418

Query: 376 KGERGSPG----SDGKPGYPGKPGLDGPKGNPGL------------PGPKGDPGVGGPPG 419
            GE G PG    + GKPG PG PGL G  G  GL            PGP+G  G  GPPG
Sbjct: 419 PGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPG 478

Query: 420 ----------------LPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFP 463
                            PGP+GP G  G+PG  G  G  G PG  GT+G  GPPG  G P
Sbjct: 479 GRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPP 538

Query: 464 GSKGDPGSPGPPGPAGI----------ATKGLNGPTGPPGPPGP------RGHSGEPGLP 507
           G  G  G+ GPPG  G             KG  GP GPPG PG        GH+GE G P
Sbjct: 539 GLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDP 598

Query: 508 GP--------------PGPPGPPGQA--VMPEGFIKAGQ-----RPSLSGTPLVSANQGV 546
           GP              PGP GPPG+A  V P G    G       P + G P V    G+
Sbjct: 599 GPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGL 658

Query: 547 TGMPVSAFTVILSKAYPAIGTPIPFD 572
            G      T+  +  YP    P  FD
Sbjct: 659 KGQ--KGDTISCNVTYPGRHGPPGFD 682



 Score =  285 bits (728), Expect = 1e-76
 Identities = 175/372 (47%), Positives = 201/372 (54%), Gaps = 51/372 (13%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVPGL 113
            ++G +G+PG PGP      PG SGPPG PG +G PGL+G+PG  G PGP   G  G PG+
Sbjct: 1110 IQGPRGSPGRPGP------PGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR--GLQGDPGI 1161

Query: 114  PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI-----PGPAGISVPGKPGQQGPTGAPG 168
            PG PG +GP G  G  G  GL G +G  G  G+     PGP GI  PG  G++G  G+PG
Sbjct: 1162 PGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI--PGLKGERGDPGSPG 1219

Query: 169  --PRGFPGEKGAPGVPGMNGQKGEMGYGA--------PGRPGERGLPGPQGPTGPSGPPG 218
              P G  G+KG PG PG +G  G  G           PG PG++G PGP GP G  GPPG
Sbjct: 1220 ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPG 1279

Query: 219  VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGI 277
            +       V    G  GD G PG   P GPPGP GPPG +G  G  GK G  G  G PG 
Sbjct: 1280 L----PGSVDLLRGEPGDCGLPG---PPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGP 1332

Query: 278  PGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGP----------AGLPGGPGAKGEQG 326
             G  G PG PG  G PGPPG  G  GLPG +GE GP           GLPG PG +G +G
Sbjct: 1333 QGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEG 1392

Query: 327  PAGLPGK-----PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381
              GLPG      PG  G PG  G +G  G+PGS G PG KG+TG  G  G PG  G  G 
Sbjct: 1393 AMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGD 1452

Query: 382  PGSDG-KPGYPG 392
            PG  G  PGY G
Sbjct: 1453 PGPKGFGPGYLG 1464



 Score =  268 bits (684), Expect = 2e-71
 Identities = 175/435 (40%), Positives = 207/435 (47%), Gaps = 82/435 (18%)

Query: 206 GPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IG 264
           GP G    S    V ++G  G PG PG +      G +GP+G PGP G  GE+G  G  G
Sbjct: 45  GPCGGRDCSVCHCVPEKGSRGPPGPPGPQ------GPIGPLGAPGPIGLSGEKGMRGDRG 98

Query: 265 KPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKG 323
            PGAAG  G  G  G  G PG  GI G PGPPG  GKPG+ G  G RG  G PGG GA G
Sbjct: 99  PPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALG 158

Query: 324 EQGPAGLPGKPGLTGPP-----GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
             GP G PG+ G  G          G QG +G PG  GLPG  G  GPAGP GYPG  G 
Sbjct: 159 PGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGL 218

Query: 379 RGSPGSDGKPGYPGKPGL--------DGPKGNPGLPGP------------KGDPGVGGPP 418
            G PG  G+PG  G PG+         G  G  G PGP            KG+ G+ G P
Sbjct: 219 VGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIP 278

Query: 419 GLPGPVGPAGAK--------------GMPGHNGEAGPRGAPGIPGTRGP---IGPPGIPG 461
           G+ G  GP G K              G PG  G+ G  G+PG PG +G    +G PG+ G
Sbjct: 279 GMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFG 338

Query: 462 FPGSKGDPGSPGPPGPAGIATK---GLNGPTGPPGPPGPRGHSGEPGLPGPP-------- 510
             G KGDPG+ G PGP G+       L GP G PG PG  G +G+ G PGPP        
Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398

Query: 511 ------GPPGP---------PGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFT 555
                 GPPGP         PG+A +P     A  +P   G+P +    G+ G+P S   
Sbjct: 399 ACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGS--- 455

Query: 556 VILSKAYPAIGTPIP 570
              S  Y ++G P P
Sbjct: 456 ---SVIYCSVGNPGP 467



 Score =  201 bits (512), Expect = 1e-51
 Identities = 123/262 (46%), Positives = 141/262 (53%), Gaps = 55/262 (20%)

Query: 50   SKGIAVRGEQGTPGPPGPAGPRGHPGPSGP----------PGKPG-YGSPGLQGEPGLPG 98
            S GI+  G +G  GPPGP G  G PGP+G           PG PG  G PG  G  G PG
Sbjct: 1217 SPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276

Query: 99   PPG-PSAV----GKPGVPGLPGKPGERGPYGPKG------------DVGPAGLPGPRGPP 141
            PPG P +V    G+PG  GLPG PG  GP GP G              GP G PGP+GP 
Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPH 1336

Query: 142  GPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEK----------GAPGVPGMNGQKGEM 191
            G PG PG  G+  PG PG++GPTG PGPRG PG            G PG PGM G +G M
Sbjct: 1337 GFPGPPGEKGL--PGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAM 1394

Query: 192  GYGAPGRPGERGLPGPQGPTGPS--GPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGP 248
            G           LPG +GP+GP   G PG+ G+RG +GVPG PG  G +G  GE G  G 
Sbjct: 1395 G-----------LPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGG 1443

Query: 249  PGPQGPPGERGPEGIGKPGAAG 270
            PGP GP G+ GP+G G PG  G
Sbjct: 1444 PGPPGPIGDPGPKGFG-PGYLG 1464


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  438 bits (1127), Expect = e-123
 Identities = 278/638 (43%), Positives = 320/638 (50%), Gaps = 122/638 (19%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-- 85
            P G +G  P T  +  +P     KG   +   G PGPPGP G  G PG  GPPG PG   
Sbjct: 662  PQGDRG-FPGTPGRPGLP---GEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPG 717

Query: 86   -----GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYG------PKGDVGPAGL 134
                 G+PG+QG+ G PG   P   G PG+PG+PG PGE+G  G        G +GP GL
Sbjct: 718  FNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGL 777

Query: 135  PGPRGPPGPPGIPGPAGI-SVPG--------KPGQQGPTGAPGPRGFPGEKGAPGVPGMN 185
             G RG PGPPG+PG  G   VPG         PG QGP G  GP G  GEKG PG PG++
Sbjct: 778  QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLD 837

Query: 186  --GQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGV-------------- 227
              G KG+ G  G PG  G+ GLPG  G  G  G PG  G +GE GV              
Sbjct: 838  MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG 897

Query: 228  -PGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG------------------------ 262
             PG PG KGD GFPG  GP G PG +G  G+ G  G                        
Sbjct: 898  APGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKG 957

Query: 263  ----IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF----GKPGLPGLKGERGPAG 314
                IG+ G+ G PG PG+PG  G  G PG  GP G PG     G PGLPG KG  G  G
Sbjct: 958  QIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMG 1017

Query: 315  LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPG 374
            LPG PG KG  G  G  G PGL G  G  G +G  G PG  G+PG +GE G  G AG+PG
Sbjct: 1018 LPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI-GIPGLRGEKGDQGIAGFPG 1076

Query: 375  AKGERGSPGSDGKPGYPGKPGLDGP------KGNPGLPGPKGDPGV------------GG 416
            + GE+G  GS G PG PG PGL G        G+PGLPG KGD G+             G
Sbjct: 1077 SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAG 1136

Query: 417  PPGLPGPVGPAGAKGMPGHN---GEAGPRGAPGIP--------------GTRGPIGPPGI 459
             PG PGP GPAG KG PG +   G AG +G PG+P              G++G +G PG+
Sbjct: 1137 LPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGL 1196

Query: 460  ---PGFPGSKGDPGSPGPPGPAGIATKGLNGPTG--PPGPPGPRGHSGEPGLPGPPGPPG 514
               PG PGSKG+ G  GPPGP G    GL G  G    GP G RG  G+PGLPG PGP G
Sbjct: 1197 AGSPGIPGSKGEQGFMGPPGPQG--QPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMG 1254

Query: 515  PPGQAVMP--EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            PPG   +   +G       P   G P    + G  GMP
Sbjct: 1255 PPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMP 1292



 Score =  436 bits (1121), Expect = e-122
 Identities = 275/658 (41%), Positives = 327/658 (49%), Gaps = 164/658 (24%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPG-PSAVG 106
            G+ + G +G PG PG  G  G  G  G PG PG     G PGLQG  G PGPPG P +VG
Sbjct: 735  GVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG 794

Query: 107  KPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGA 166
             PGVPG+ G PG RGP G +G   P GL GP G  G  G PG  G+ +PG  G +G  G 
Sbjct: 795  SPGVPGI-GPPGARGPPGGQG---PPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGL 850

Query: 167  PGPRG------FPGEKGAPGVPGMNGQKGEMGY-------------GAPGRPGERGLPGP 207
            PG  G       PG++GAPG+PG  G KGEMG              GAPG PGE+G  G 
Sbjct: 851  PGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGF 910

Query: 208  QGPTGPSGPPGV-GKRGENGVPGQPGI------------KGDRGFPGEMGPIGPPGPQGP 254
             G +GP G PG+ G +G+ G+PG+PG             KGD+G  G++GPIG  G +G 
Sbjct: 911  PGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGD 970

Query: 255  PGERGPEGI-------------GKPGAAGAPGQPGIPGTKG------LPGAPGIAGPPG- 294
            PG  G  G              G PG +G PG PG+PG KG      LPG PG  G PG 
Sbjct: 971  PGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGI 1030

Query: 295  -----------------------PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331
                                   PPG G PGL G KG++G AG PG PG KGE+G  G+P
Sbjct: 1031 PGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090

Query: 332  G---KPGLTGPPGNMG---------PQGPKGIPGSHGLPGPKGE---------TGPAGPA 370
            G    PGL G PG++G          +G KG+PG  G+PG KGE         TGPAG  
Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 371  GYPGAKGERGSPGSDGKPGYPGK--PGLDGPKGNPGLPGPKGDPGVGGPPGLPG------ 422
            G PG+ G  GS G  G+PG PG+  PG  G KG+ G  G  G PG+ G PG+PG      
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 423  ---PVGPAGAKGMPGHNGEA--------GPRGAPGIPGTRGPIGPPGIPGFPGSKGD--- 468
               P GP G  G+PG  G A        GP+G PG+PG  GP+GPPG+PG  G KGD   
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270

Query: 469  ---PGSPGPPGPAG----------------IATKGLNGPTGPPGPPGPR----------- 498
               PG+PG PGP G                  +KG  GP G PG  GP+           
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 499  -GHSGEPGLPGPPGPPGPPG--QAVMPEGFIKAGQRP----SLSGTPLVSANQGVTGM 549
             G  G PG  G PGPPGPPG    +  E  +   + P     L G P     QGVTG+
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388



 Score =  421 bits (1082), Expect = e-117
 Identities = 280/673 (41%), Positives = 320/673 (47%), Gaps = 153/673 (22%)

Query: 25   YQMPTGIKGP--------LPNTKTQFFIPYTIKSKGIA-VRGEQGTPGPPGPAGPRGHPG 75
            Y+ P G +GP         P  K    +P      G+A V G QGTPG  G  G +G PG
Sbjct: 475  YRGPPGPQGPPGEIGFPGQPGAKGDRGLP---GRDGVAGVPGPQGTPGLIGQPGAKGEPG 531

Query: 76   P-------------SGPPGKPGY----GSPGLQGEPGLPGPPG-PSAVG------KPGVP 111
                           G PG+PG     GSPG  G PGLPGP G P +VG       PG  
Sbjct: 532  EFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGV 591

Query: 112  GLPGKPGERGP-----YGPKGDVGPAGLPGPRGPPGPPGIPGPAG-----ISVPGKPGQQ 161
            G PG  G+ GP     YGP G +G  G  G  G PG PG+PGP G     + +PG PG +
Sbjct: 592  GFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAE 651

Query: 162  GPTGAPG------PRGFPGEKGAPGVPGMNGQKGEMGYG--------------------- 194
            G  G+PG       RGFPG  G PG+PG  G  G+ G G                     
Sbjct: 652  GLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPG 711

Query: 195  APGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRG---------FPGEMGP 245
             PGRPG  GLPG  G  G  G PGVG  G  G+PG PGI G  G          PGE G 
Sbjct: 712  TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGA 771

Query: 246  IGPPGPQGPPGERGPEG------------IGKPGAAGAP---------GQPGIPGTKGLP 284
            IGPPG QG  GE GP G            IG PGA G P         G PGI G KG P
Sbjct: 772  IGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFP 831

Query: 285  GAPGI--AGPPGPPG-------FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG 335
            G PG+   GP G  G        G+ GLPGL G++G  G+PG PG+KGE G  G PG+PG
Sbjct: 832  GFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPG 891

Query: 336  LTGP---PGNMGPQGPKGIPGS---HGLPGPKGETGPAGPAGYPGA---------KGER- 379
              GP   PG  G +G  G PGS    G PG KG+ G  G  G PG+         KG++ 
Sbjct: 892  SPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKG 951

Query: 380  -----------GSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAG 428
                       G  GS G PG PG PG DG  G PG PGPKGDPG+ G PG PG  GP G
Sbjct: 952  DQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKG 1011

Query: 429  AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG---PAGIATKGL 485
            + G  G  G  G +G PGIP   GP G PG+PG  G+KG+ G  GPPG   P     KG 
Sbjct: 1012 SVGGMGLPGTPGEKGVPGIP---GPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGD 1068

Query: 486  NGPTGPPGPPGPRGHSGE---PGLPGPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGT 537
             G  G PG PG +G  G    PG+PG PG  G PG    P      G++     P L G 
Sbjct: 1069 QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGI 1128

Query: 538  PLVSANQGVTGMP 550
            P V    G+ G P
Sbjct: 1129 PGVKGEAGLPGTP 1141



 Score =  417 bits (1072), Expect = e-116
 Identities = 264/649 (40%), Positives = 300/649 (46%), Gaps = 166/649 (25%)

Query: 57  GEQGTPGPPGPAGPRGHPGP--------------------SGPPGKPGY----------- 85
           G  G  GPPGP GP G PG                     SGPPG PG            
Sbjct: 197 GPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFAT 256

Query: 86  -GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD---------------V 129
            G  G +GEPG  G PG    G+PG PG  GKPG+ G  G KG                 
Sbjct: 257 KGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQ 316

Query: 130 GPAGLPGPRGPPGPPGI---PGPAG-ISVPGKPGQQGPTGAPGPRGF------------- 172
           GP G  G  GPPGPPGI    GP G     G PG  GP G PGP+GF             
Sbjct: 317 GPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP 376

Query: 173 -PGEKGAPGVPGMNGQKGEMGY---GAPGRPGERGLPGPQGPTGPSGPPGV--------- 219
            PG+ GAPG PG  G+KG+ G+     PG  G  GLPGP G  GP G PG          
Sbjct: 377 VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQP 436

Query: 220 ---GKRGENGVPGQPGIKGDRGFPGEMGPI----------GPPGPQGPPGERGPEGIGKP 266
              G +G  G+PGQPG  G+ G  G+ G            GPPGPQGPPGE         
Sbjct: 437 GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGE--------- 487

Query: 267 GAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPGLPG----------LKGERGP 312
              G PGQPG  G +GLPG  G+AG PGP G     G+PG  G          LKG++G 
Sbjct: 488 --IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGD 545

Query: 313 AGLPGGPGAKGEQGPAGLPGKPGLTGP---PGNMGPQGPKGIPGSHGLPGPKGETGPAGP 369
            G PG PG  G  G  G  G PGL GP   PG++G +G +G PG  G PG +G+TGP GP
Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGP 605

Query: 370 --------------AGYPGAKGERGSPGSDGKPG----YPGKPGLDGPKGNPGLPGPKGD 411
                         AG+PG  G  G PG  G+PG     PG PG +G  G+PG PGP+GD
Sbjct: 606 PGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGD 665

Query: 412 PGVGGPPGLPGPVGPAGAKGMP--GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDP 469
            G  G PG PG  G  GA G P  G  G  GP+G  G+PG  GP G PG PGF G  G+P
Sbjct: 666 RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNP 725

Query: 470 GSPGPPGPAGI---ATKGLNGPTGPPGPPGPRGHSGEPGLP---------------GPPG 511
           G  G  G  G+     KGL G  G PG PG +G  G PG+P               G PG
Sbjct: 726 GVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPG 785

Query: 512 PPGPPGQAVMP--EGFIKAGQR--------PSLSGTPLVSANQGVTGMP 550
           PPG PG    P   G    G R        P LSG P +   +G  G P
Sbjct: 786 PPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFP 834



 Score =  416 bits (1068), Expect = e-116
 Identities = 269/623 (43%), Positives = 307/623 (49%), Gaps = 140/623 (22%)

Query: 28   PTGIKGP--LPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG- 84
            P G KG   LP    Q  +P         + G+QG PG PG  G +G  G  G PG+PG 
Sbjct: 841  PKGDKGAQGLPGITGQSGLP--------GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS 892

Query: 85   ---YGSPGLQGE------PGLPGPPG-PSAVGKPGVPGLPGKPG------------ERGP 122
                G+PGL GE      PG  GP G P   G  G  GLPGKPG            ++G 
Sbjct: 893  PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGD 952

Query: 123  YGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVP 182
             G KG +GP G  G RG PG PG        VPGK GQ G  G PGP+G PG  G PG P
Sbjct: 953  QGEKGQIGPIGEKGSRGDPGTPG--------VPGKDGQAGQPGQPGPKGDPGISGTPGAP 1004

Query: 183  GMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-VGKRGENGVPGQPGI------- 233
            G+ G KG +G  G PG PGE+G+PG  GP G  G PG  G +GE G  G PGI       
Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064

Query: 234  -KGDRG---FPG------EMGPIGPPGPQGPPGERG-PEGIGKPGAAGAPGQPG------ 276
             KGD+G   FPG      E G IG PG  G PG +G P  +G PG+ G PG+ G      
Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG 1124

Query: 277  ---IPGTKGLPGAPGIAGPPGPPGF----GKPGLPGLKGERGPAGLPGG-----PGAKGE 324
               IPG KG  G PG  GP GP G     G  G+PG  GE+G  GLPG      PGAKG+
Sbjct: 1125 LDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGD 1184

Query: 325  QGPAGLPGKPGLTGPPGN---------MGPQGPKGIPGSHGLPG-----PKGETGPAGPA 370
            +G  G  G PGL G PG          MGP GP+G PG  G PG     PKG+ GP G  
Sbjct: 1185 KGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQP 1244

Query: 371  GYPGAKGERGSPG---------SDGKPGYPGKPGLDGPKGNPG---LPGPKGDPGVGG-- 416
            G PG  G  G PG           G PG+PG PG+ GPKG+PG   +PG  G PG+ G  
Sbjct: 1245 GLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSK 1304

Query: 417  ----PPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI-------PGFPGS 465
                PPG+PG  GP G  G+ G  G+ G +G PG  G  GP GPPG        PG PG 
Sbjct: 1305 GDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGP 1364

Query: 466  KGDPGS------PGP------------PGPAGI----ATKGLNGPTGPPGPPGPRGHSGE 503
            +G PG       PGP            PGP GI       G  G  GP GP GPRG  G 
Sbjct: 1365 EGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGP 1424

Query: 504  PGLPGPPGPPGPPGQAVMPEGFI 526
            PG  G PG  GPPG   +  GF+
Sbjct: 1425 PGPDGLPGSMGPPGTPSVDHGFL 1447



 Score =  415 bits (1067), Expect = e-116
 Identities = 275/652 (42%), Positives = 304/652 (46%), Gaps = 161/652 (24%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGVP 111
           +GE+G PG  G  G  G  GP GP G PG     G PGL G  G  GPPG S  G PG P
Sbjct: 48  KGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGAS--GYPGNP 105

Query: 112 GLPGKPGERGPYGP------------KGDVGPAGLPGPRGPPGPPGIPG----------- 148
           GLPG PG+ GP GP            +G +GP GLPG  G PGPPG+PG           
Sbjct: 106 GLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGH 165

Query: 149 ---------------PAGISVPGKPGQQGPT---------GAPGPRGFPGEK-------- 176
                          P     PG PG QGP          G PGP G PGEK        
Sbjct: 166 VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQ 225

Query: 177 ------------GAPGVPGM--------------NGQKGEMGY---------GAPGRPGE 201
                       G PGVPG                GQKGE G+         G PG+PG 
Sbjct: 226 GPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGP 285

Query: 202 RGLPGPQGPTGPSGPPGV----------------GKRGENGVPGQPGI---------KGD 236
           RG PG  G  G  G PG                 G++GE G PG PGI         KG+
Sbjct: 286 RGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGE 345

Query: 237 RGFPGEMGPIGPPGPQ---GPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPP 293
           RG+PG  GP G PGP+   G PG+ GP G+  PG AGAPG PG  G KG  G PG    P
Sbjct: 346 RGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPG-TSLP 404

Query: 294 GPPGFGKPGLPGLKGERGPAGLPG--------GPGAKGEQGPAGLPGKPGLTGPPGNMGP 345
           GP   G+ GLPG  G  GP G PG         PG  G+QGP G+PG+PG  G  G  G 
Sbjct: 405 GPS--GRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462

Query: 346 QGPK----GIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
           +G       I G  G PGP+G  G  G  G PGAKG+RG PG DG  G PG  G  G  G
Sbjct: 463 KGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIG 522

Query: 402 NPGLPGP----------KGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTR 451
            PG  G           KGD G  G PG PG  G AG+ G  GH G  GP+G+PG  G +
Sbjct: 523 QPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLK 582

Query: 452 GPIGPPGIPGFPGSKGDPGSPGPP--GPAG-IATKGLNGPTGPPGPPGPRGHSGEPG--- 505
           G  GPPG  GFPGS+GD G PGPP  GPAG I  KG  G  G PG PG  G  GEPG   
Sbjct: 583 GERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIV 642

Query: 506 -LPGPPGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMPVSAF 554
            LPGPPG  G PG    P      G R  P   G P +   +G  G P   F
Sbjct: 643 PLPGPPGAEGLPGSPGFPG---PQGDRGFPGTPGRPGLPGEKGAVGQPGIGF 691



 Score =  404 bits (1037), Expect = e-112
 Identities = 267/670 (39%), Positives = 306/670 (45%), Gaps = 183/670 (27%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY------GSPGLQGE---------------- 93
            RG  GTPGP G  GP+G PG  G PG PG       G+PG  GE                
Sbjct: 346  RGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPG 405

Query: 94   ----------PGLPGPPG------------PSAVGKPGVPGLPGKPGERGPYGPKGDVGP 131
                      PG PGPPG            P   G  G PG+PG+PG  G  G KG  G 
Sbjct: 406  PSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGE 465

Query: 132  A----------GLPGPRGPPGPPGIPG-PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPG 180
            +          G PGP+GPPG  G PG P      G PG+ G  G PGP+G PG  G PG
Sbjct: 466  SCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPG 525

Query: 181  VPG----------MNGQKGEMGY----------GAPGRPGERGLPGPQGPTGPSGPPGVG 220
              G          + G KG+ G+          G+PGR G  GLPGP+G      P  VG
Sbjct: 526  AKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG-----SPGSVG 580

Query: 221  KRGENGVPGQPGIKGDRGFPGEMGPIGPP--GPQGPPGERGPEGI-GKPGAAGAPGQ--- 274
             +GE G PG  G  G R   G+ GP GPP  GP GP G++G  G  G PG+ G PG    
Sbjct: 581  LKGERGPPGGVGFPGSR---GDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGE 637

Query: 275  -------PGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPG----GP--- 319
                   PG PG +GLPG+PG  GP G  GF G PG PGL GE+G  G PG    GP   
Sbjct: 638  PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP 697

Query: 320  ----GAKGEQGPAGLPGKPGLTGPPGNMGPQGP-----------KGIPGSHGLPGPKGET 364
                G  G+ GP G PG+PG  G PGN G QG            KG+PG  G+PG  GE 
Sbjct: 698  KGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEK 757

Query: 365  GPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGL-----PGPKGDPGVGGPPG 419
            G  G  G PG  G  G PG  G  G PG PGL G  G+PG+     PG +G PG  GPPG
Sbjct: 758  GSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPG 817

Query: 420  LPGPVGPAGAKG--------MPGHNGEAGPRGAPGI------PGTRGPIGPPGIPGFPGS 465
            L GP G  G KG        MPG  G+ G +G PGI      PG  G  G PGIPGFPGS
Sbjct: 818  LSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGS 877

Query: 466  KGD------PGSPGPPGPAGI-------ATKGLNGPTGPPGPPGPRGHSGEPGLPGPP-- 510
            KG+      PG PG PGP G           G  G +GP G PG +G  G+ GLPG P  
Sbjct: 878  KGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGS 937

Query: 511  ----------------------------GPPGPPGQAVMPEGFIKAGQ--RPSLSGTPLV 540
                                        G  G PG   +P    +AGQ  +P   G P +
Sbjct: 938  MDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGI 997

Query: 541  SANQGVTGMP 550
            S   G  G+P
Sbjct: 998  SGTPGAPGLP 1007



 Score =  369 bits (946), Expect = e-102
 Identities = 230/523 (43%), Positives = 258/523 (49%), Gaps = 76/523 (14%)

Query: 69  GPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKG 127
           G +G  G  G PG  G  G PG+QG  G  GPPG    G  G PGLPG  G RGP G  G
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQK--GDTGEPGLPGTKGTRGPPGASG 100

Query: 128 ---DVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGM 184
              + G  G+PG  GPPGPPGIPG       G  G++GP G PG  GF G  G PG+PGM
Sbjct: 101 YPGNPGLPGIPGQDGPPGPPGIPG-----CNGTKGERGPLGPPGLPGFAGNPGPPGLPGM 155

Query: 185 NGQKGEMGYGAPGR--PGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE 242
            G  GE+    PG    GERG PG  G  GP              PG PG++G  G PG 
Sbjct: 156 KGDPGEILGHVPGMLLKGERGFPGIPGTPGP--------------PGLPGLQGPVGPPGF 201

Query: 243 MGPIGPPGPQGPPGERGPEGI------GKPGAAGAPGQPGIPG-----------TKGLPG 285
            GP GPPGP GPPGE+G  G+      G  G  G  G PG+PG           TKG  G
Sbjct: 202 TGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKG 261

Query: 286 APGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGP 345
             G  G  G PG G+ G PG   + GP G PG  G KGE+G  G PG+PG  G  G  GP
Sbjct: 262 QKGEPGFQGMPGVGEKGEPG---KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP 318

Query: 346 QGPKGIPGSHGLPG------PKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGL--D 397
           QG KG  G  G PG      P GE G  G  G PG +GE G  G  G PG PG PGL   
Sbjct: 319 QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVP 378

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGI--------PG 449
           G  G PG PG +G+ G  G PG   P GP+G  G+PG  G  GP G PG         PG
Sbjct: 379 GQAGAPGFPGERGEKGDRGFPGTSLP-GPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPG 437

Query: 450 TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA--TKGLNGPTGPPGPPGPRGHSGEPGLP 507
             G  GPPGIPG PG  G+ G  G  G + +     G  GP GP GPPG  G  G+PG  
Sbjct: 438 PPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAK 497

Query: 508 GPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
           G  G PG  G A +          P   GTP +    G  G P
Sbjct: 498 GDRGLPGRDGVAGV----------PGPQGTPGLIGQPGAKGEP 530



 Score =  201 bits (511), Expect = 2e-51
 Identities = 137/358 (38%), Positives = 151/358 (42%), Gaps = 109/358 (30%)

Query: 297 GFGKPGLPGLKGERGPAGL------------------------------PGGPGAKGEQG 326
           G GK    G+KG++G  GL                              PG PG KG +G
Sbjct: 35  GCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 327 P---AGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGP---------AGPAGYPG 374
           P   +G PG PGL G PG  GP GP GIPG +G  G +G  GP          GP G PG
Sbjct: 95  PPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG 154

Query: 375 ----------------AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP---------- 408
                            KGERG PG  G PG PG PGL GP G PG  GP          
Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214

Query: 409 ----------------KGDPGVGGPPGLPGPV-----GPAGAKGMPGHNGEAGPRGAPGI 447
                           KGD GV GPPG+PG       G    KG  G  GE G +G PG+
Sbjct: 215 GEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV 274

Query: 448 -----PGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI----ATKGLNGPTGPPGPP--- 495
                PG  GP G PG  G  G KG PG PG PG  G+      +G  G  GPPGPP   
Sbjct: 275 GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 496 ---GPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
              GP G  GE G PG PGP G PG    P+GF     +P   G P V    G  G P
Sbjct: 335 IGTGPLGEKGERGYPGTPGPRGEPG----PKGFPGLPGQPGPPGLP-VPGQAGAPGFP 387


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  436 bits (1122), Expect = e-122
 Identities = 250/515 (48%), Positives = 276/515 (53%), Gaps = 53/515 (10%)

Query: 56   RGEQGTPGPPG---PAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV-GKPGV 110
            RGE+G PG  G   P GP G  GPSGPPG  G  G PG+ G  G  GP GPS + G+ G 
Sbjct: 588  RGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA 647

Query: 111  PGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGP 169
             G+PG  GE+G  G +G++G  G  G RG PG  G PGPAG +   G+ G  GP G  GP
Sbjct: 648  AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707

Query: 170  RGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQG---------------PTGP 213
            RG PGE+G  G  G NG  G  G  G PG  GERG  GP+G               P GP
Sbjct: 708  RGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGP 767

Query: 214  SGPPG-VGKRGENGVPGQ---PGIKGDRGFPGEMGPIGPPGPQGPPGE---RGPEG---- 262
            +GPPG  G RG+ G PG    PG  G  G PG  G  GPPGP GP G+   RGP G    
Sbjct: 768  NGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGP 827

Query: 263  IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPGLPGLKGERGPAGLPGG 318
            +G+ G  GA G PG  G KG  G  G AGPPG PG     G PG+ GL G RG  GLPG 
Sbjct: 828  VGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGV 887

Query: 319  PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
             GA GE GP G+ G PG  GPPG +G  G  G PG  G  G  G  GP G  G PG KGE
Sbjct: 888  AGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGE 947

Query: 379  RGSPGSDGKPGYPGKPGLDGP------KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGM 432
            RG PG+ G  G  G PG  GP       GN G  GP G  G  G  G  GP GP G +G 
Sbjct: 948  RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGD 1007

Query: 433  PGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA----------T 482
             G  GE GPRG PG+ G  G  G PGI G  G +G PGS GP GP G A           
Sbjct: 1008 KGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGR 1067

Query: 483  KGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517
             G  G  GP G  GP+GH G  G PGPPGPPGPPG
Sbjct: 1068 TGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPG 1102



 Score =  420 bits (1080), Expect = e-117
 Identities = 262/591 (44%), Positives = 293/591 (49%), Gaps = 102/591 (17%)

Query: 56  RGEQGTPGPPG------PAGPRGHPGPSGPPGKPG-----------------YGSPGLQG 92
           RGE+G PGPPG      P GP G PGP GPPG  G                  G  G +G
Sbjct: 41  RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100

Query: 93  EPGLPGPPGPSA----VGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
            PG  G PGP       G+PG PG  G  G RGP GP G  G  G PG  G PG  G+ G
Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160

Query: 149 PAGI-SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPG 206
           P G    PG PG  G  G  G  G  G KG PG PG+ G+ G  G  G PG+ G RGLPG
Sbjct: 161 PQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPG 220

Query: 207 PQGPTGPSGPPG----------------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250
            +G  G  GP G                +G  G  G PG PG KG+ G  G  GP GP G
Sbjct: 221 ERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAG 280

Query: 251 PQ------------GPPGERGPEGI-GKPGAAGAP---GQPGIPGTKGLPGAPGIAGPPG 294
           P+            GPPG  G  G+ G  GAAG P   G PG+PG +G+PG  G AG  G
Sbjct: 281 PRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATG 340

Query: 295 PPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI-- 351
             G  G+PG  G KGE G  G PG  G +G  GP+G  GK G  G  G+ GP GP G+  
Sbjct: 341 ARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRG 400

Query: 352 -PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG 410
            PGS GLPG  G  G  GP G  GA G  G  G +G  G PG+PGL GP+G PG PG  G
Sbjct: 401 SPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIG 460

Query: 411 DPGVGGPPGL------PGPVGPAGAKGMP---------------------GHNGEAGPRG 443
             G  GP GL      PGP+GPAGA+G P                     GH G AG RG
Sbjct: 461 PAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARG 520

Query: 444 APGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGE 503
           APG  G  G  GPPG  G  G KG+ G PGPPG  G+   G +GP G  G PG RG  GE
Sbjct: 521 APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGL--PGPSGPAGEVGKPGERGLHGE 578

Query: 504 PGLPGPPGP---PGPPGQ--AVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
            GLPGP GP    GPPG+  A  P G I  G R   SG P    N+G  G+
Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTGPI--GSR-GPSGPPGPDGNKGEPGV 626



 Score =  411 bits (1056), Expect = e-114
 Identities = 270/634 (42%), Positives = 304/634 (47%), Gaps = 116/634 (18%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGH------PGPSGPPG 81
           P G  GP+ +     F P     KG    G  G  GP GPAGPRG        GP GPPG
Sbjct: 242 PVGPAGPIGSAGPPGF-PGAPGPKGEI--GAVGNAGPAGPAGPRGEVGLPGLSGPVGPPG 298

Query: 82  KPGY----------GSPGLQGEPGLPGPPG-PSAVGKPGVPGLPGKPGERGPYGPKGDVG 130
            PG           G PG+ G PGLPGP G P  VG  G  G  G  GE GP G KG+ G
Sbjct: 299 NPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESG 358

Query: 131 PAGLPGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPRGFPGEKGAPGV-------- 181
             G PG  GP GPPG  G  G   P G+ G  GP G PG RG PG +G PG         
Sbjct: 359 NKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMG 418

Query: 182 -PGMNGQKGEMGYGAP----GRPGE------RGLPGPQGPTGPSGPPG-VGKRGENGVPG 229
            PG  G  G  G   P    GRPGE      RGLPG  G  GP+G  G VG  G +G PG
Sbjct: 419 PPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPG 478

Query: 230 QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPG 288
             G  G RG PG +G  GP GP G PG+ G +G  G  GA GAPG  G  G +G PG  G
Sbjct: 479 PIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQG 538

Query: 289 IAG------PPGPPGF----------GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPG 332
           + G      PPGPPGF          G+ G PG +G  G  GLPG  G +GE+GP G  G
Sbjct: 539 VQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESG 598

Query: 333 KPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
             G TGP G+ GP GP G  G+ G PG  G  G AGP+G  G  GERG+ G  G  G  G
Sbjct: 599 AAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKG 658

Query: 393 KPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG 452
           +PGL G  GNPG  G +G PG  G PG  G  G  G  G  G  G AGPRG+PG  G  G
Sbjct: 659 EPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVG 718

Query: 453 P------IGPPGIPGFPGSKGDPGSPGPPGPAG-------IATKGLNGPTGPPGPPGPRG 499
           P       GP G  G PG+KG+ G+ GP G  G       +   G  GP GPPGP G RG
Sbjct: 719 PAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRG 778

Query: 500 HSGEP------------------GLPGPPGPPGPPGQ--------------------AVM 521
             G P                  G+ GPPGPPGP G+                    AV 
Sbjct: 779 DGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVG 838

Query: 522 PEGFIKAGQR-PS----LSGTPLVSANQGVTGMP 550
           P GF  AG++ PS     +G P     QG+ G P
Sbjct: 839 PPGF--AGEKGPSGEAGTAGPPGTPGPQGLLGAP 870



 Score =  404 bits (1039), Expect = e-112
 Identities = 246/538 (45%), Positives = 273/538 (50%), Gaps = 82/538 (15%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV-GKPGVPGLP 114
            G  G  GPPGP G +G  G  GPPG PG+ G PG  G  G  G PG   + G+ G+PG  
Sbjct: 526  GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585

Query: 115  GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174
            G  GERGP G  G  GP G  G RGP GPPG  G  G   PG  G  G  G  GP G PG
Sbjct: 586  GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKG--EPGVVGAVGTAGPSGPSGLPG 643

Query: 175  EKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPG---------------------PQG 209
            E+GA G+PG  G+KGE G     G PGR G RG PG                     P G
Sbjct: 644  ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703

Query: 210  PTGPSGPPG----VGKRGENG------VPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259
            P GP G PG    VG  G NG        GQPG KG+RG  G  G  G  GP GP G  G
Sbjct: 704  PAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAG 763

Query: 260  PEGI-GKPGAAGAPGQPGIPGTKGLPGAPG---------IAGPPGPPG-FGKPGLPGLKG 308
            P G  G PG AG+ G  G PG  G PGA G         I+GPPGPPG  GK GL G +G
Sbjct: 764  PAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRG 823

Query: 309  ERGPAGLPGG------PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362
            ++GP G  G       PG  GE+GP+G   + G  GPPG  GPQG  G PG  GLPG +G
Sbjct: 824  DQGPVGRTGEVGAVGPPGFAGEKGPSG---EAGTAGPPGTPGPQGLLGAPGILGLPGSRG 880

Query: 363  ETG------------PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG 410
            E G            P G AG PGA+G  G+ GS G  G PG+ G DG  GN G PG  G
Sbjct: 881  ERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDG 940

Query: 411  DPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP---------IGPPGIPG 461
             PG  G  G PG +GP GA G PG +G  GP G  G  G  GP         +GP G  G
Sbjct: 941  QPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSG 1000

Query: 462  FPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519
              G +GD G PG  GP G+   GL G  G  G PG  GH G+ G PG  GP GP G A
Sbjct: 1001 PQGIRGDKGEPGEKGPRGLP--GLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPA 1056



 Score =  355 bits (912), Expect = 6e-98
 Identities = 225/501 (44%), Positives = 248/501 (49%), Gaps = 76/501 (15%)

Query: 90  LQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
           LQ E    GP G     G+ G PG PG+ GE GP GP         PGP GPPGPPG+ G
Sbjct: 25  LQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGP---------PGPPGPPGPPGLGG 75

Query: 149 PAGISVPGKPGQ--QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPG 206
                  GK      GP G  GPRG PG  GAPG  G  G  GE        PGE G  G
Sbjct: 76  NFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGE--------PGEPGQTG 127

Query: 207 PQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKP 266
           P G  GP+GPPG  K GE+G PG+PG       PGE G +GP G +G PG  G      P
Sbjct: 128 PAGARGPAGPPG--KAGEDGHPGKPGR------PGERGVVGPQGARGFPGTPG-----LP 174

Query: 267 GAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQG 326
           G  G  G  G+ G KG PGAPG+ G PG PG  + G PG  G RG   LPG  G  G  G
Sbjct: 175 GFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG--ENGTPGQTGARG---LPGERGRVGAPG 229

Query: 327 PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGP---AGPAGYPGAKGERGSPG 383
           PAG  G  G  GP G  GP G  G PG  G PGPKGE G    AGPAG  G +GE G PG
Sbjct: 230 PAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPG 289

Query: 384 SDGKPGYPGKPG---LDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAG 440
             G  G PG PG   L G KG  GLPG  G PG+ GP G+PGPVG AGA G  G  GE G
Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPG 349

Query: 441 P---------RGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI----------- 480
           P         +G PG  G +GP GP G  G  G  G+ GS GPPGP G+           
Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPG 409

Query: 481 -----------ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAG 529
                       ++G +GP G  GP G  G  GEPGL GP G PG PG  + P G     
Sbjct: 410 ADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGN-IGPAGKEGPV 468

Query: 530 QRPSLSGTPLVSANQGVTGMP 550
             P + G P      G  G P
Sbjct: 469 GLPGIDGRPGPIGPAGARGEP 489



 Score =  263 bits (673), Expect = 3e-70
 Identities = 150/321 (46%), Positives = 165/321 (51%), Gaps = 32/321 (9%)

Query: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK------ 300
           GP G +GP GERGP           PG PG  G  G  G PG  GPPGPPG G       
Sbjct: 33  GPAGDRGPRGERGP-----------PGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQY 81

Query: 301 --------PGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIP 352
                   PG  GL G RGP G  G PG +G QGPAG PG+PG TGP G  GP GP G  
Sbjct: 82  DGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKA 141

Query: 353 GSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP 412
           G  G PG  G  G  G  G  GA+G  G+PG  G  G  G  GLDG KG PG PG KG+P
Sbjct: 142 GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEP 201

Query: 413 GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472
           G  G  G PG  G  G  G  G  G  GP GA G  G+ GP+GP G  G  G  G PG+P
Sbjct: 202 GAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAP 261

Query: 473 GPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRP 532
           GP G  G       G  GP GP GPRG  G PGL GP GPPG PG   +  G   A   P
Sbjct: 262 GPKGEIGAV-----GNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL-TGAKGAAGLP 315

Query: 533 SLSGTPLVSANQGVTGMPVSA 553
            ++G P +   +G+ G PV A
Sbjct: 316 GVAGAPGLPGPRGIPG-PVGA 335



 Score = 75.1 bits (183), Expect = 2e-13
 Identities = 44/95 (46%), Positives = 49/95 (51%), Gaps = 19/95 (20%)

Query: 57   GEQGTPGPPGPAGPRGHP---GPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGL 113
            G QG PG  G  G +G P   GP+GP G                GP GP+  GK G  G 
Sbjct: 1027 GLQGLPGIAGHHGDQGAPGSVGPAGPRGP--------------AGPSGPA--GKDGRTGH 1070

Query: 114  PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
            PG  G  G  GP+G  GPAG PGP GPPGPPG+ G
Sbjct: 1071 PGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 21/44 (47%), Positives = 22/44 (50%), Gaps = 9/44 (20%)

Query: 483 KGLNGPTGPPGPPGPRGHSGEPGLPGPP---------GPPGPPG 517
           + L   T   GP G RG  GE G PGPP         GPPGPPG
Sbjct: 23  QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPG 66



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 20/37 (54%), Positives = 21/37 (56%), Gaps = 2/37 (5%)

Query: 45   PYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPG 81
            P T+   GI  RG QG  GP GP GP G PGP G  G
Sbjct: 1071 PGTVGPAGI--RGPQGHQGPAGPPGPPGPPGPPGVSG 1105


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  436 bits (1121), Expect = e-122
 Identities = 249/552 (45%), Positives = 290/552 (52%), Gaps = 95/552 (17%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSA----VGKPGVP 111
            G +G  G PGP GPRG  GP GP GKPG  G PG  G  G+PG PG        G PG+P
Sbjct: 562  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 621

Query: 112  GLPGKPGERGPYGP------------KGDVGPAGLP---------GPRGPPGPPGIPGPA 150
            G  G  GERGP GP             G++GP GLP         GPRG PG PG PG A
Sbjct: 622  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 151  GISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY------- 193
            G+  P          G+PG  G  G PGP+G PG +G  G PG  G +G+ G        
Sbjct: 682  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741

Query: 194  GAPGRPGERGL---------PGPQGPTGPSGPPGV-------------GKRGENGVP--- 228
            G PG PG+ G          PGPQGP G  GP GV             G++GE+G P   
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 229  GQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288
            G  G+KGDRG  G++GP G  GP+GP G  GP   G PG +G  G+ G  G  GLPG PG
Sbjct: 802  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP--TGDPGPSGQAGEKGKLGVPGLPGYPG 859

Query: 289  IAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP 348
              GP G  GF  PG PG  GE+G  G+ G PG +G++GP G  G  G  GP G  GP+G 
Sbjct: 860  RQGPKGSTGF--PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 917

Query: 349  KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP 408
             G  G  G PG +G  GP GP G+PG KG  G PG DG PG+PG+ G  G +G  G PGP
Sbjct: 918  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 977

Query: 409  KGDPGVGGPP---------GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI 459
             G  G  GP          G PGP GP G +G+PG  G+ G +G PG  G  G  GP G+
Sbjct: 978  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL 1037

Query: 460  PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGE------PGLPGPP 510
             GFPG +G PG+ G PG      KG  GP GPPGP   PG RG +G       PG PGP 
Sbjct: 1038 RGFPGERGLPGAQGAPG-----LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1092

Query: 511  GPPGPPGQAVMP 522
            GPPGP G+   P
Sbjct: 1093 GPPGPAGEKGAP 1104



 Score =  433 bits (1113), Expect = e-121
 Identities = 255/566 (45%), Positives = 294/566 (51%), Gaps = 75/566 (13%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV----GK 107
            RG  G PG PG  G RG  GP GPPG PG     G  G  G  GLPG  GP  +    G 
Sbjct: 612  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 671

Query: 108  PGVPGLPGKPGERGPYGPKGDVGPAGLPGP---RGPPGPPGIPGPAGISVPGKPGQQGPT 164
            PG PG PG  G  GP GPKG++GP G PGP   +G PGP G+PGP G    G PG++GP 
Sbjct: 672  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPGEKGPQ 729

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV---- 219
            G PG  G PG  G PG PG  GQ GE G  G PG  G  G PGP+G  G  G  G+    
Sbjct: 730  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 789

Query: 220  GKRGENGVPG---QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-------------I 263
            G++GE+G PG     G+KGDRG  G++GP G  GP+GP G  GP G             +
Sbjct: 790  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 849

Query: 264  GKPGAAGAPGQ---------PGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPA 313
            G PG  G PG+         PG PG  G  GA G+AG PGP G  G  G  G +G RGP 
Sbjct: 850  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 909

Query: 314  GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG---PQGPKGIPGSHGLPGP---------K 361
            G PG  G  G  GP G PG+ G  GP G +G   P+GP G PG  GLPG          +
Sbjct: 910  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 969

Query: 362  GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLP 421
            G+TGP GP G  G +G  G  G  G+ G+PG PG  G +G PG  G +G  G  GP G+ 
Sbjct: 970  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1029

Query: 422  GPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD------------P 469
            G  GPAG +G PG  G  G +GAPG+ G  GP GPPG  G PG +G             P
Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1089

Query: 470  GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAG 529
            G  GPPGPAG   KG  G  GP GP G  G  G  GLPGP GP G PG+        + G
Sbjct: 1090 GPQGPPGPAG--EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1147

Query: 530  QRPSL-----SGTPLVSANQGVTGMP 550
            Q+ S      +G P     QG  G P
Sbjct: 1148 QKGSKGDKGENGPPGPPGLQGPVGAP 1173



 Score =  433 bits (1113), Expect = e-121
 Identities = 243/488 (49%), Positives = 275/488 (56%), Gaps = 31/488 (6%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPS-AVGKPGVP 111
            I + G  G  GPPGPAG +G PG  GP G  G    G+QG  GLPGP GP+ + G+ G  
Sbjct: 1083 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDK 1140

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI------PGPAGIS-VPGKPGQQGPT 164
            G  G+PG++G  G KG+ GP G PG +GP G PGI      PGP G   + G+ G +G  
Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-VGKR 222
            G PGP G  G +G PG PG  G+ G++G  G PG PG RG  GP G  GP GPPG VG  
Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTK 281
            G  G  G+PG  G+ G PGE G  GP G +G  GE GP G  G PGA G PG  G  G  
Sbjct: 1261 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1320

Query: 282  GLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK---PGLT 337
            G  G PG  GPPG PG  G+ G+ G KGE G  G PG PG  GE GP G PGK   PG  
Sbjct: 1321 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1380

Query: 338  GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
            G  G  G +G KG  G+ G PG  G  GP GPAG PG +G RG PG  G+ G PG  G D
Sbjct: 1381 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1440

Query: 398  GPKGN---PGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
            GP G    PGLPG KGDPG  G  G PG +G  G    PG  GE G RG PG  G+ G  
Sbjct: 1441 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGTQGSPGAK 1497

Query: 455  GPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPG 514
            G  GIPG  G  G PG PG PGP         GP G  G  GP G  G+ GLPGPPG PG
Sbjct: 1498 GDGGIPGPAGPLGPPGPPGLPGP--------QGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549

Query: 515  PPGQAVMP 522
            PPG+ + P
Sbjct: 1550 PPGEVIQP 1557



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/595 (44%), Positives = 294/595 (49%), Gaps = 88/595 (14%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPG------PAGPRGHPGPSGPPG 81
            P G +GP     ++     T K       G  G PGPPG      P GP G PGP GPPG
Sbjct: 890  PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 949

Query: 82   KPGY----GSPGLQGEPGLPG---PPGPSAV-------------------GKPGVPGLPG 115
             PG     G PG +GE G  G   PPGP  V                   G PG PG  G
Sbjct: 950  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 1009

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRG 171
             PG  G  G KGD GP G+ G  GP G  G PG  G+      PG  G +GP G PGP G
Sbjct: 1010 LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG 1069

Query: 172  FPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRG 223
             PGE+G+ G  G  G  G  G  G PG  GE+G PG +GP GP+G  GV       G  G
Sbjct: 1070 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129

Query: 224  ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKG 282
              G PG+ G KG+ G PG+ G  G  G  GPPG  G +G +G PG AG  G+PG  G +G
Sbjct: 1130 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1189

Query: 283  L------PGAPGIAGPPGPPGF-GKPGLPGLKGERG---PAGLPGGPGAKGEQGPAGLPG 332
            +       GA G  GPPGP G  G PG PG KGE G   P G PG PG +G QGP G  G
Sbjct: 1190 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1249

Query: 333  KPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
              G  G  G++G  G KG PG  G PGP GE G  GP G  G KGE G PG+ G PG  G
Sbjct: 1250 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1309

Query: 393  KPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG 452
             PG DGPKGN   PGP G PG  GPPG PGP G  G  G  G +G+ G  G PG  G  G
Sbjct: 1310 PPGDDGPKGN---PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1366

Query: 453  PIGPPGIPGFP------------GSKGDPGSPGPPGPAGIATKGLNGPTGPPGP------ 494
            P GPPG  G P            G+KG+ G+ GPPG  G    G  GP G PGP      
Sbjct: 1367 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG--PVGPQGPAGKPGPEGLRGI 1424

Query: 495  PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
            PGP G  G PG  G  GPPGP G    P G       P L G P     +G  G+
Sbjct: 1425 PGPVGEQGLPGAAGQDGPPGPMG----PPGL------PGLKGDPGSKGEKGHPGL 1469



 Score =  412 bits (1060), Expect = e-115
 Identities = 257/603 (42%), Positives = 290/603 (48%), Gaps = 114/603 (18%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV-- 105
            G+ V G  G  GP G  GP G  GP+GPPG PG     G PGL G  GLPGPPG   +  
Sbjct: 449  GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 508

Query: 106  --------------------------------GKPGVPGLPGKPGERGPYGPKGDVGPAG 133
                                            G PG  GL G+PG  G  G  G  G +G
Sbjct: 509  FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568

Query: 134  LPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA---------PGVPGM 184
             PGP+GP G  G PGP      GKPG++G  GA G RG PGE GA         PG+PG 
Sbjct: 569  DPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623

Query: 185  NGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGD 236
             G +GE G  G PG PG+ G+ G  G  GP G PG       +G RG  G PGQPG+ G 
Sbjct: 624  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683

Query: 237  RGFPGEMGPIGP------------PGPQ---------GPPGERGPEGIGKPGAAGAP--- 272
             G PG  G +GP            PGPQ         GPPGE+GP+  GKPG AG P   
Sbjct: 684  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ--GKPGLAGLPGAD 741

Query: 273  GQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331
            G PG PG +G  G  G  GPPGP G  G PG  G+KG  G  GL G  G KGE G  G  
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 332  GKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYP 391
            G  GL G  G +G  GP+   G  G  GPKG  GP G  G  G  GE+G  G  G PGYP
Sbjct: 802  GDMGLKGDRGEVGQIGPR---GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 858

Query: 392  GKPGLDGPKGNPGLPGPKGDPGVGGPPGLP------GPVGPAGAKGMPGHNGEAGPRGA- 444
            G+ G  G  G PG PG  G+ G  G  G P      GP GP G++G  G  G+ GP+G  
Sbjct: 859  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918

Query: 445  -----PGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG----PAGIATKGLNGPTGPP--- 492
                 PG PG RGP GP G  GFPG KG PG PG  G    P      G  G TGPP   
Sbjct: 919  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978

Query: 493  ---GPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVT 547
               GP GP G +G  G  G PGPPGPPG+  +P    K G +  P   G        G+ 
Sbjct: 979  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1038

Query: 548  GMP 550
            G P
Sbjct: 1039 GFP 1041



 Score =  389 bits (1000), Expect = e-108
 Identities = 242/571 (42%), Positives = 277/571 (48%), Gaps = 126/571 (22%)

Query: 81  GKPGYGSPGLQGEPGL-------PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAG 133
           G   YG  G +GEP +        GPPGP+     G  G+ G PG +GP GP GD     
Sbjct: 430 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPA-----GPAGIMGPPGLQGPTGPPGD----- 479

Query: 134 LPGPRGPPGPPGIPGPAGISVP-----------GKPGQQGPT------------------ 164
            PG RGPPG PG+PG  G+  P           G  G +GPT                  
Sbjct: 480 -PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA 538

Query: 165 --GAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGK 221
             G PGP G  G  G  G PG +G KGE   G PG  G RG+ GP GPTG  G  G  G 
Sbjct: 539 LRGPPGPMGLTGRPGPVGGPGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGA 596

Query: 222 RGENGVPGQPGIKGDRGFP------------GEMGPIGPPGPQGPPGERGPEG----IGK 265
            G  G+PG+PG KGDRGF             GE GP GPPGP G  G RG +G     G 
Sbjct: 597 DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGL 656

Query: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------FGKPGLPGLKGERGPAGLP-- 316
           PG AG  G  G  GT G PG PG+AG  GPPG        G+PG PG +G  GP GLP  
Sbjct: 657 PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 716

Query: 317 ----GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372
               G PG KG QG  GL G PG  GPPG+ G +G  G  G+ G PGP+G  G  GP G 
Sbjct: 717 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 776

Query: 373 PGA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGP 426
            GA      KG +G  G DG PG+ G  GL G +G  G  GP+G+ G  GP G  GP G 
Sbjct: 777 KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 836

Query: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------PGP------ 474
            G  G  G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+      PGP      
Sbjct: 837 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896

Query: 475 ---------------PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519
                          PGP G  T G +GP GPPG  GP+G  G  G PGP GPPGPPG+ 
Sbjct: 897 TGPRGSRGARGPTGKPGPKG--TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 954

Query: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            +P      GQR         +  QG TG P
Sbjct: 955 GLPG---HPGQRGE-------TGFQGKTGPP 975



 Score =  292 bits (748), Expect = 6e-79
 Identities = 186/486 (38%), Positives = 224/486 (46%), Gaps = 92/486 (18%)

Query: 137 PRGPPGP---PGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193
           P  PP     PG+P    I+     G        G  G  G+KG P V     + G +  
Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGH-------GAYGEKGQKGEPAVV----EPGMLVE 453

Query: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPI------- 246
           G PG  G  G+ GP G  GP+GPPG    G+ G PG+PG+ G  G PG  G +       
Sbjct: 454 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 511

Query: 247 -----------------------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGI 277
                                        GPPGP G  G  GP  +G PG++GA G+ G 
Sbjct: 512 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGD 569

Query: 278 PGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLT 337
           PG +G     G+ GPPGP G  KPG  G  G  G  G+PG PGAKG++G  GLPG PG  
Sbjct: 570 PGPQG---PRGVQGPPGPTG--KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 624

Query: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
           G  G  GPQGP G PG  G+ G  GE GP G  G  G +G  G  G+ G PG PG  G+D
Sbjct: 625 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 684

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457
           GP G  G  GP+G+PG  G  G PGP G  G +G  G  GE GP+G PG+ G  G  GPP
Sbjct: 685 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744

Query: 458 GIPGFPGSKGDPGSPGPPGPAG----IATKGLNGPTGPPGPPGPRGHSGEPGLP------ 507
           G PG  G  G+ G+ GPPGP G       +G+ G  G  G  G +G  GE G P      
Sbjct: 745 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804

Query: 508 ------------------GPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGTPLVSANQ 544
                             GP GP G  G    P    +AG++     P L G P     +
Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864

Query: 545 GVTGMP 550
           G TG P
Sbjct: 865 GSTGFP 870



 Score =  224 bits (570), Expect = 3e-58
 Identities = 141/343 (41%), Positives = 161/343 (46%), Gaps = 84/343 (24%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKP---- 108
            G  G PGP GP GP G  GP GPPG  G     G  G  GE G PGPPG + VG P    
Sbjct: 1231 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1290

Query: 109  ------GVPGLPGKPGERGPYG---PKGDVGPAGLPGPRGPPGPPGIPGPAGISV----- 154
                  G PG  G PG +GP G   PKG+ GP G PG  GPPG PG  G  G+       
Sbjct: 1291 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1350

Query: 155  --PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPGPQ 208
              PG+PG  GP+G  GP G PG++G PG  G  G++GE G     GA G PG+ G  GPQ
Sbjct: 1351 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1410

Query: 209  GPTGPSGPPGV----GKRGENGVPG---------------------QPGIKGDRGFPGEM 243
            GP G  GP G+    G  GE G+PG                      PG KG++G PG +
Sbjct: 1411 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1470

Query: 244  GPIGPPGPQGPPGERGPEGI-GKPGAAG------------APGQPGIPGTKG-------- 282
            G IGPPG QG  G+RG  G  G PGA G             PG PG+PG +G        
Sbjct: 1471 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530

Query: 283  ----------LPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL 315
                      LPG PG  GPPG      P L   K  R   G+
Sbjct: 1531 GPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1573



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 8/113 (7%)

Query: 445 PGIPG----TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGH 500
           PG+P     T   I   G  G  G KG+P    P    G+  +G  GP GP G  GP G 
Sbjct: 415 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPAGPAGIMGPPGL 470

Query: 501 SGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSA 553
            G  G PG PG  GPPG+  +P      G   ++   P      G  G  +SA
Sbjct: 471 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 523



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 44   IPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG---PSGPPGKPGYGSP----GLQGEPGL 96
            +P T  S G   +G+ G PGP GP GP G PG   P GP G  G   P    G  G PG 
Sbjct: 1487 LPGTQGSPG--AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1544

Query: 97   PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD 128
            PG PGP       +P L  K   R   G + D
Sbjct: 1545 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQAD 1576


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  436 bits (1121), Expect = e-122
 Identities = 249/552 (45%), Positives = 290/552 (52%), Gaps = 95/552 (17%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSA----VGKPGVP 111
            G +G  G PGP GPRG  GP GP GKPG  G PG  G  G+PG PG        G PG+P
Sbjct: 511  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 570

Query: 112  GLPGKPGERGPYGP------------KGDVGPAGLP---------GPRGPPGPPGIPGPA 150
            G  G  GERGP GP             G++GP GLP         GPRG PG PG PG A
Sbjct: 571  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 151  GISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY------- 193
            G+  P          G+PG  G  G PGP+G PG +G  G PG  G +G+ G        
Sbjct: 631  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690

Query: 194  GAPGRPGERGL---------PGPQGPTGPSGPPGV-------------GKRGENGVP--- 228
            G PG PG+ G          PGPQGP G  GP GV             G++GE+G P   
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 229  GQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288
            G  G+KGDRG  G++GP G  GP+GP G  GP   G PG +G  G+ G  G  GLPG PG
Sbjct: 751  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP--TGDPGPSGQAGEKGKLGVPGLPGYPG 808

Query: 289  IAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP 348
              GP G  GF  PG PG  GE+G  G+ G PG +G++GP G  G  G  GP G  GP+G 
Sbjct: 809  RQGPKGSTGF--PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 866

Query: 349  KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP 408
             G  G  G PG +G  GP GP G+PG KG  G PG DG PG+PG+ G  G +G  G PGP
Sbjct: 867  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 926

Query: 409  KGDPGVGGPP---------GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI 459
             G  G  GP          G PGP GP G +G+PG  G+ G +G PG  G  G  GP G+
Sbjct: 927  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL 986

Query: 460  PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGE------PGLPGPP 510
             GFPG +G PG+ G PG      KG  GP GPPGP   PG RG +G       PG PGP 
Sbjct: 987  RGFPGERGLPGAQGAPG-----LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1041

Query: 511  GPPGPPGQAVMP 522
            GPPGP G+   P
Sbjct: 1042 GPPGPAGEKGAP 1053



 Score =  433 bits (1113), Expect = e-121
 Identities = 255/566 (45%), Positives = 294/566 (51%), Gaps = 75/566 (13%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV----GK 107
            RG  G PG PG  G RG  GP GPPG PG     G  G  G  GLPG  GP  +    G 
Sbjct: 561  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 620

Query: 108  PGVPGLPGKPGERGPYGPKGDVGPAGLPGP---RGPPGPPGIPGPAGISVPGKPGQQGPT 164
            PG PG PG  G  GP GPKG++GP G PGP   +G PGP G+PGP G    G PG++GP 
Sbjct: 621  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPGEKGPQ 678

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV---- 219
            G PG  G PG  G PG PG  GQ GE G  G PG  G  G PGP+G  G  G  G+    
Sbjct: 679  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 738

Query: 220  GKRGENGVPG---QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-------------I 263
            G++GE+G PG     G+KGDRG  G++GP G  GP+GP G  GP G             +
Sbjct: 739  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 798

Query: 264  GKPGAAGAPGQ---------PGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPA 313
            G PG  G PG+         PG PG  G  GA G+AG PGP G  G  G  G +G RGP 
Sbjct: 799  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 858

Query: 314  GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG---PQGPKGIPGSHGLPGP---------K 361
            G PG  G  G  GP G PG+ G  GP G +G   P+GP G PG  GLPG          +
Sbjct: 859  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 918

Query: 362  GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLP 421
            G+TGP GP G  G +G  G  G  G+ G+PG PG  G +G PG  G +G  G  GP G+ 
Sbjct: 919  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 978

Query: 422  GPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD------------P 469
            G  GPAG +G PG  G  G +GAPG+ G  GP GPPG  G PG +G             P
Sbjct: 979  GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1038

Query: 470  GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAG 529
            G  GPPGPAG   KG  G  GP GP G  G  G  GLPGP GP G PG+        + G
Sbjct: 1039 GPQGPPGPAG--EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1096

Query: 530  QRPSL-----SGTPLVSANQGVTGMP 550
            Q+ S      +G P     QG  G P
Sbjct: 1097 QKGSKGDKGENGPPGPPGLQGPVGAP 1122



 Score =  433 bits (1113), Expect = e-121
 Identities = 243/488 (49%), Positives = 275/488 (56%), Gaps = 31/488 (6%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPS-AVGKPGVP 111
            I + G  G  GPPGPAG +G PG  GP G  G    G+QG  GLPGP GP+ + G+ G  
Sbjct: 1032 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDK 1089

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI------PGPAGIS-VPGKPGQQGPT 164
            G  G+PG++G  G KG+ GP G PG +GP G PGI      PGP G   + G+ G +G  
Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-VGKR 222
            G PGP G  G +G PG PG  G+ G++G  G PG PG RG  GP G  GP GPPG VG  
Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTK 281
            G  G  G+PG  G+ G PGE G  GP G +G  GE GP G  G PGA G PG  G  G  
Sbjct: 1210 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1269

Query: 282  GLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK---PGLT 337
            G  G PG  GPPG PG  G+ G+ G KGE G  G PG PG  GE GP G PGK   PG  
Sbjct: 1270 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1329

Query: 338  GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
            G  G  G +G KG  G+ G PG  G  GP GPAG PG +G RG PG  G+ G PG  G D
Sbjct: 1330 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1389

Query: 398  GPKGN---PGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
            GP G    PGLPG KGDPG  G  G PG +G  G    PG  GE G RG PG  G+ G  
Sbjct: 1390 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGTQGSPGAK 1446

Query: 455  GPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPG 514
            G  GIPG  G  G PG PG PGP         GP G  G  GP G  G+ GLPGPPG PG
Sbjct: 1447 GDGGIPGPAGPLGPPGPPGLPGP--------QGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498

Query: 515  PPGQAVMP 522
            PPG+ + P
Sbjct: 1499 PPGEVIQP 1506



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/595 (44%), Positives = 294/595 (49%), Gaps = 88/595 (14%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPG------PAGPRGHPGPSGPPG 81
            P G +GP     ++     T K       G  G PGPPG      P GP G PGP GPPG
Sbjct: 839  PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 898

Query: 82   KPGY----GSPGLQGEPGLPG---PPGPSAV-------------------GKPGVPGLPG 115
             PG     G PG +GE G  G   PPGP  V                   G PG PG  G
Sbjct: 899  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 958

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRG 171
             PG  G  G KGD GP G+ G  GP G  G PG  G+      PG  G +GP G PGP G
Sbjct: 959  LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG 1018

Query: 172  FPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRG 223
             PGE+G+ G  G  G  G  G  G PG  GE+G PG +GP GP+G  GV       G  G
Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078

Query: 224  ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKG 282
              G PG+ G KG+ G PG+ G  G  G  GPPG  G +G +G PG AG  G+PG  G +G
Sbjct: 1079 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1138

Query: 283  L------PGAPGIAGPPGPPGF-GKPGLPGLKGERG---PAGLPGGPGAKGEQGPAGLPG 332
            +       GA G  GPPGP G  G PG PG KGE G   P G PG PG +G QGP G  G
Sbjct: 1139 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198

Query: 333  KPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
              G  G  G++G  G KG PG  G PGP GE G  GP G  G KGE G PG+ G PG  G
Sbjct: 1199 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1258

Query: 393  KPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG 452
             PG DGPKGN   PGP G PG  GPPG PGP G  G  G  G +G+ G  G PG  G  G
Sbjct: 1259 PPGDDGPKGN---PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1315

Query: 453  PIGPPGIPGFP------------GSKGDPGSPGPPGPAGIATKGLNGPTGPPGP------ 494
            P GPPG  G P            G+KG+ G+ GPPG  G    G  GP G PGP      
Sbjct: 1316 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG--PVGPQGPAGKPGPEGLRGI 1373

Query: 495  PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
            PGP G  G PG  G  GPPGP G    P G       P L G P     +G  G+
Sbjct: 1374 PGPVGEQGLPGAAGQDGPPGPMG----PPGL------PGLKGDPGSKGEKGHPGL 1418



 Score =  412 bits (1060), Expect = e-115
 Identities = 257/603 (42%), Positives = 290/603 (48%), Gaps = 114/603 (18%)

Query: 52  GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV-- 105
           G+ V G  G  GP G  GP G  GP+GPPG PG     G PGL G  GLPGPPG   +  
Sbjct: 398 GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 457

Query: 106 --------------------------------GKPGVPGLPGKPGERGPYGPKGDVGPAG 133
                                           G PG  GL G+PG  G  G  G  G +G
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517

Query: 134 LPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA---------PGVPGM 184
            PGP+GP G  G PGP      GKPG++G  GA G RG PGE GA         PG+PG 
Sbjct: 518 DPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572

Query: 185 NGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGD 236
            G +GE G  G PG PG+ G+ G  G  GP G PG       +G RG  G PGQPG+ G 
Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 632

Query: 237 RGFPGEMGPIGP------------PGPQ---------GPPGERGPEGIGKPGAAGAP--- 272
            G PG  G +GP            PGPQ         GPPGE+GP+  GKPG AG P   
Sbjct: 633 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ--GKPGLAGLPGAD 690

Query: 273 GQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331
           G PG PG +G  G  G  GPPGP G  G PG  G+KG  G  GL G  G KGE G  G  
Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 332 GKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYP 391
           G  GL G  G +G  GP+   G  G  GPKG  GP G  G  G  GE+G  G  G PGYP
Sbjct: 751 GDMGLKGDRGEVGQIGPR---GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807

Query: 392 GKPGLDGPKGNPGLPGPKGDPGVGGPPGLP------GPVGPAGAKGMPGHNGEAGPRGA- 444
           G+ G  G  G PG PG  G+ G  G  G P      GP GP G++G  G  G+ GP+G  
Sbjct: 808 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867

Query: 445 -----PGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG----PAGIATKGLNGPTGPP--- 492
                PG PG RGP GP G  GFPG KG PG PG  G    P      G  G TGPP   
Sbjct: 868 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927

Query: 493 ---GPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVT 547
              GP GP G +G  G  G PGPPGPPG+  +P    K G +  P   G        G+ 
Sbjct: 928 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 987

Query: 548 GMP 550
           G P
Sbjct: 988 GFP 990



 Score =  389 bits (1000), Expect = e-108
 Identities = 242/571 (42%), Positives = 277/571 (48%), Gaps = 126/571 (22%)

Query: 81  GKPGYGSPGLQGEPGL-------PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAG 133
           G   YG  G +GEP +        GPPGP+     G  G+ G PG +GP GP GD     
Sbjct: 379 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPA-----GPAGIMGPPGLQGPTGPPGD----- 428

Query: 134 LPGPRGPPGPPGIPGPAGISVP-----------GKPGQQGPT------------------ 164
            PG RGPPG PG+PG  G+  P           G  G +GPT                  
Sbjct: 429 -PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA 487

Query: 165 --GAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGK 221
             G PGP G  G  G  G PG +G KGE   G PG  G RG+ GP GPTG  G  G  G 
Sbjct: 488 LRGPPGPMGLTGRPGPVGGPGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGA 545

Query: 222 RGENGVPGQPGIKGDRGFP------------GEMGPIGPPGPQGPPGERGPEG----IGK 265
            G  G+PG+PG KGDRGF             GE GP GPPGP G  G RG +G     G 
Sbjct: 546 DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGL 605

Query: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------FGKPGLPGLKGERGPAGLP-- 316
           PG AG  G  G  GT G PG PG+AG  GPPG        G+PG PG +G  GP GLP  
Sbjct: 606 PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 665

Query: 317 ----GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372
               G PG KG QG  GL G PG  GPPG+ G +G  G  G+ G PGP+G  G  GP G 
Sbjct: 666 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725

Query: 373 PGA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGP 426
            GA      KG +G  G DG PG+ G  GL G +G  G  GP+G+ G  GP G  GP G 
Sbjct: 726 KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785

Query: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------PGP------ 474
            G  G  G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+      PGP      
Sbjct: 786 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845

Query: 475 ---------------PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519
                          PGP G  T G +GP GPPG  GP+G  G  G PGP GPPGPPG+ 
Sbjct: 846 TGPRGSRGARGPTGKPGPKG--TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 903

Query: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            +P      GQR         +  QG TG P
Sbjct: 904 GLPG---HPGQRGE-------TGFQGKTGPP 924



 Score =  292 bits (748), Expect = 6e-79
 Identities = 186/486 (38%), Positives = 224/486 (46%), Gaps = 92/486 (18%)

Query: 137 PRGPPGP---PGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193
           P  PP     PG+P    I+     G        G  G  G+KG P V     + G +  
Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGH-------GAYGEKGQKGEPAVV----EPGMLVE 402

Query: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPI------- 246
           G PG  G  G+ GP G  GP+GPPG    G+ G PG+PG+ G  G PG  G +       
Sbjct: 403 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 460

Query: 247 -----------------------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGI 277
                                        GPPGP G  G  GP  +G PG++GA G+ G 
Sbjct: 461 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGD 518

Query: 278 PGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLT 337
           PG +G     G+ GPPGP G  KPG  G  G  G  G+PG PGAKG++G  GLPG PG  
Sbjct: 519 PGPQG---PRGVQGPPGPTG--KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 573

Query: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
           G  G  GPQGP G PG  G+ G  GE GP G  G  G +G  G  G+ G PG PG  G+D
Sbjct: 574 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 633

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457
           GP G  G  GP+G+PG  G  G PGP G  G +G  G  GE GP+G PG+ G  G  GPP
Sbjct: 634 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693

Query: 458 GIPGFPGSKGDPGSPGPPGPAG----IATKGLNGPTGPPGPPGPRGHSGEPGLP------ 507
           G PG  G  G+ G+ GPPGP G       +G+ G  G  G  G +G  GE G P      
Sbjct: 694 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753

Query: 508 ------------------GPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGTPLVSANQ 544
                             GP GP G  G    P    +AG++     P L G P     +
Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 545 GVTGMP 550
           G TG P
Sbjct: 814 GSTGFP 819



 Score =  224 bits (570), Expect = 3e-58
 Identities = 141/343 (41%), Positives = 161/343 (46%), Gaps = 84/343 (24%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKP---- 108
            G  G PGP GP GP G  GP GPPG  G     G  G  GE G PGPPG + VG P    
Sbjct: 1180 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1239

Query: 109  ------GVPGLPGKPGERGPYG---PKGDVGPAGLPGPRGPPGPPGIPGPAGISV----- 154
                  G PG  G PG +GP G   PKG+ GP G PG  GPPG PG  G  G+       
Sbjct: 1240 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1299

Query: 155  --PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPGPQ 208
              PG+PG  GP+G  GP G PG++G PG  G  G++GE G     GA G PG+ G  GPQ
Sbjct: 1300 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1359

Query: 209  GPTGPSGPPGV----GKRGENGVPG---------------------QPGIKGDRGFPGEM 243
            GP G  GP G+    G  GE G+PG                      PG KG++G PG +
Sbjct: 1360 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1419

Query: 244  GPIGPPGPQGPPGERGPEGI-GKPGAAG------------APGQPGIPGTKG-------- 282
            G IGPPG QG  G+RG  G  G PGA G             PG PG+PG +G        
Sbjct: 1420 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479

Query: 283  ----------LPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL 315
                      LPG PG  GPPG      P L   K  R   G+
Sbjct: 1480 GPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1522



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 8/113 (7%)

Query: 445 PGIPG----TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGH 500
           PG+P     T   I   G  G  G KG+P    P    G+  +G  GP GP G  GP G 
Sbjct: 364 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPAGPAGIMGPPGL 419

Query: 501 SGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSA 553
            G  G PG PG  GPPG+  +P      G   ++   P      G  G  +SA
Sbjct: 420 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 472



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 44   IPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG---PSGPPGKPGYGSP----GLQGEPGL 96
            +P T  S G   +G+ G PGP GP GP G PG   P GP G  G   P    G  G PG 
Sbjct: 1436 LPGTQGSPG--AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1493

Query: 97   PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD 128
            PG PGP       +P L  K   R   G + D
Sbjct: 1494 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQAD 1525


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  436 bits (1121), Expect = e-122
 Identities = 249/552 (45%), Positives = 290/552 (52%), Gaps = 95/552 (17%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSA----VGKPGVP 111
            G +G  G PGP GPRG  GP GP GKPG  G PG  G  G+PG PG        G PG+P
Sbjct: 550  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 609

Query: 112  GLPGKPGERGPYGP------------KGDVGPAGLP---------GPRGPPGPPGIPGPA 150
            G  G  GERGP GP             G++GP GLP         GPRG PG PG PG A
Sbjct: 610  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 151  GISVP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY------- 193
            G+  P          G+PG  G  G PGP+G PG +G  G PG  G +G+ G        
Sbjct: 670  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729

Query: 194  GAPGRPGERGL---------PGPQGPTGPSGPPGV-------------GKRGENGVP--- 228
            G PG PG+ G          PGPQGP G  GP GV             G++GE+G P   
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 229  GQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPG 288
            G  G+KGDRG  G++GP G  GP+GP G  GP   G PG +G  G+ G  G  GLPG PG
Sbjct: 790  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGP--TGDPGPSGQAGEKGKLGVPGLPGYPG 847

Query: 289  IAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP 348
              GP G  GF  PG PG  GE+G  G+ G PG +G++GP G  G  G  GP G  GP+G 
Sbjct: 848  RQGPKGSTGF--PGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGT 905

Query: 349  KGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP 408
             G  G  G PG +G  GP GP G+PG KG  G PG DG PG+PG+ G  G +G  G PGP
Sbjct: 906  SGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGP 965

Query: 409  KGDPGVGGPP---------GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGI 459
             G  G  GP          G PGP GP G +G+PG  G+ G +G PG  G  G  GP G+
Sbjct: 966  GGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGL 1025

Query: 460  PGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGE------PGLPGPP 510
             GFPG +G PG+ G PG      KG  GP GPPGP   PG RG +G       PG PGP 
Sbjct: 1026 RGFPGERGLPGAQGAPG-----LKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQ 1080

Query: 511  GPPGPPGQAVMP 522
            GPPGP G+   P
Sbjct: 1081 GPPGPAGEKGAP 1092



 Score =  433 bits (1113), Expect = e-121
 Identities = 255/566 (45%), Positives = 294/566 (51%), Gaps = 75/566 (13%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV----GK 107
            RG  G PG PG  G RG  GP GPPG PG     G  G  G  GLPG  GP  +    G 
Sbjct: 600  RGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGT 659

Query: 108  PGVPGLPGKPGERGPYGPKGDVGPAGLPGP---RGPPGPPGIPGPAGISVPGKPGQQGPT 164
            PG PG PG  G  GP GPKG++GP G PGP   +G PGP G+PGP G    G PG++GP 
Sbjct: 660  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI--GPPGEKGPQ 717

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV---- 219
            G PG  G PG  G PG PG  GQ GE G  G PG  G  G PGP+G  G  G  G+    
Sbjct: 718  GKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSK 777

Query: 220  GKRGENGVPG---QPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-------------I 263
            G++GE+G PG     G+KGDRG  G++GP G  GP+GP G  GP G             +
Sbjct: 778  GEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKL 837

Query: 264  GKPGAAGAPGQ---------PGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPA 313
            G PG  G PG+         PG PG  G  GA G+AG PGP G  G  G  G +G RGP 
Sbjct: 838  GVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPT 897

Query: 314  GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG---PQGPKGIPGSHGLPGP---------K 361
            G PG  G  G  GP G PG+ G  GP G +G   P+GP G PG  GLPG          +
Sbjct: 898  GKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQ 957

Query: 362  GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLP 421
            G+TGP GP G  G +G  G  G  G+ G+PG PG  G +G PG  G +G  G  GP G+ 
Sbjct: 958  GKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGIS 1017

Query: 422  GPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD------------P 469
            G  GPAG +G PG  G  G +GAPG+ G  GP GPPG  G PG +G             P
Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRP 1077

Query: 470  GSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAG 529
            G  GPPGPAG   KG  G  GP GP G  G  G  GLPGP GP G PG+        + G
Sbjct: 1078 GPQGPPGPAG--EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPG 1135

Query: 530  QRPSL-----SGTPLVSANQGVTGMP 550
            Q+ S      +G P     QG  G P
Sbjct: 1136 QKGSKGDKGENGPPGPPGLQGPVGAP 1161



 Score =  433 bits (1113), Expect = e-121
 Identities = 243/488 (49%), Positives = 275/488 (56%), Gaps = 31/488 (6%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPS-AVGKPGVP 111
            I + G  G  GPPGPAG +G PG  GP G  G    G+QG  GLPGP GP+ + G+ G  
Sbjct: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG--RDGVQGPVGLPGPAGPAGSPGEDGDK 1128

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI------PGPAGIS-VPGKPGQQGPT 164
            G  G+PG++G  G KG+ GP G PG +GP G PGI      PGP G   + G+ G +G  
Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188

Query: 165  GAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-VGKR 222
            G PGP G  G +G PG PG  G+ G++G  G PG PG RG  GP G  GP GPPG VG  
Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1248

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTK 281
            G  G  G+PG  G+ G PGE G  GP G +G  GE GP G  G PGA G PG  G  G  
Sbjct: 1249 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1308

Query: 282  GLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK---PGLT 337
            G  G PG  GPPG PG  G+ G+ G KGE G  G PG PG  GE GP G PGK   PG  
Sbjct: 1309 GPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA 1368

Query: 338  GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
            G  G  G +G KG  G+ G PG  G  GP GPAG PG +G RG PG  G+ G PG  G D
Sbjct: 1369 GAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQD 1428

Query: 398  GPKGN---PGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
            GP G    PGLPG KGDPG  G  G PG +G  G    PG  GE G RG PG  G+ G  
Sbjct: 1429 GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP---PGEQGEKGDRGLPGTQGSPGAK 1485

Query: 455  GPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPG 514
            G  GIPG  G  G PG PG PGP         GP G  G  GP G  G+ GLPGPPG PG
Sbjct: 1486 GDGGIPGPAGPLGPPGPPGLPGP--------QGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537

Query: 515  PPGQAVMP 522
            PPG+ + P
Sbjct: 1538 PPGEVIQP 1545



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/595 (44%), Positives = 294/595 (49%), Gaps = 88/595 (14%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPG------PAGPRGHPGPSGPPG 81
            P G +GP     ++     T K       G  G PGPPG      P GP G PGP GPPG
Sbjct: 878  PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 937

Query: 82   KPGY----GSPGLQGEPGLPG---PPGPSAV-------------------GKPGVPGLPG 115
             PG     G PG +GE G  G   PPGP  V                   G PG PG  G
Sbjct: 938  PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQG 997

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRG 171
             PG  G  G KGD GP G+ G  GP G  G PG  G+      PG  G +GP G PGP G
Sbjct: 998  LPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVG 1057

Query: 172  FPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRG 223
             PGE+G+ G  G  G  G  G  G PG  GE+G PG +GP GP+G  GV       G  G
Sbjct: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117

Query: 224  ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKG 282
              G PG+ G KG+ G PG+ G  G  G  GPPG  G +G +G PG AG  G+PG  G +G
Sbjct: 1118 PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQG 1177

Query: 283  L------PGAPGIAGPPGPPGF-GKPGLPGLKGERG---PAGLPGGPGAKGEQGPAGLPG 332
            +       GA G  GPPGP G  G PG PG KGE G   P G PG PG +G QGP G  G
Sbjct: 1178 MFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1237

Query: 333  KPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
              G  G  G++G  G KG PG  G PGP GE G  GP G  G KGE G PG+ G PG  G
Sbjct: 1238 PQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKG 1297

Query: 393  KPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG 452
             PG DGPKGN   PGP G PG  GPPG PGP G  G  G  G +G+ G  G PG  G  G
Sbjct: 1298 PPGDDGPKGN---PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1354

Query: 453  PIGPPGIPGFP------------GSKGDPGSPGPPGPAGIATKGLNGPTGPPGP------ 494
            P GPPG  G P            G+KG+ G+ GPPG  G    G  GP G PGP      
Sbjct: 1355 PPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTG--PVGPQGPAGKPGPEGLRGI 1412

Query: 495  PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
            PGP G  G PG  G  GPPGP G    P G       P L G P     +G  G+
Sbjct: 1413 PGPVGEQGLPGAAGQDGPPGPMG----PPGL------PGLKGDPGSKGEKGHPGL 1457



 Score =  412 bits (1060), Expect = e-115
 Identities = 257/603 (42%), Positives = 290/603 (48%), Gaps = 114/603 (18%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV-- 105
            G+ V G  G  GP G  GP G  GP+GPPG PG     G PGL G  GLPGPPG   +  
Sbjct: 437  GMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLP 496

Query: 106  --------------------------------GKPGVPGLPGKPGERGPYGPKGDVGPAG 133
                                            G PG  GL G+PG  G  G  G  G +G
Sbjct: 497  FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556

Query: 134  LPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA---------PGVPGM 184
             PGP+GP G  G PGP      GKPG++G  GA G RG PGE GA         PG+PG 
Sbjct: 557  DPGPQGPRGVQGPPGPT-----GKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611

Query: 185  NGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKGD 236
             G +GE G  G PG PG+ G+ G  G  GP G PG       +G RG  G PGQPG+ G 
Sbjct: 612  KGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671

Query: 237  RGFPGEMGPIGP------------PGPQ---------GPPGERGPEGIGKPGAAGAP--- 272
             G PG  G +GP            PGPQ         GPPGE+GP+  GKPG AG P   
Sbjct: 672  DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQ--GKPGLAGLPGAD 729

Query: 273  GQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331
            G PG PG +G  G  G  GPPGP G  G PG  G+KG  G  GL G  G KGE G  G  
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 332  GKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYP 391
            G  GL G  G +G  GP+   G  G  GPKG  GP G  G  G  GE+G  G  G PGYP
Sbjct: 790  GDMGLKGDRGEVGQIGPR---GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846

Query: 392  GKPGLDGPKGNPGLPGPKGDPGVGGPPGLP------GPVGPAGAKGMPGHNGEAGPRGA- 444
            G+ G  G  G PG PG  G+ G  G  G P      GP GP G++G  G  G+ GP+G  
Sbjct: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906

Query: 445  -----PGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPG----PAGIATKGLNGPTGPP--- 492
                 PG PG RGP GP G  GFPG KG PG PG  G    P      G  G TGPP   
Sbjct: 907  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966

Query: 493  ---GPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVT 547
               GP GP G +G  G  G PGPPGPPG+  +P    K G +  P   G        G+ 
Sbjct: 967  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1026

Query: 548  GMP 550
            G P
Sbjct: 1027 GFP 1029



 Score =  389 bits (1000), Expect = e-108
 Identities = 242/571 (42%), Positives = 277/571 (48%), Gaps = 126/571 (22%)

Query: 81  GKPGYGSPGLQGEPGL-------PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAG 133
           G   YG  G +GEP +        GPPGP+     G  G+ G PG +GP GP GD     
Sbjct: 418 GHGAYGEKGQKGEPAVVEPGMLVEGPPGPA-----GPAGIMGPPGLQGPTGPPGD----- 467

Query: 134 LPGPRGPPGPPGIPGPAGISVP-----------GKPGQQGPT------------------ 164
            PG RGPPG PG+PG  G+  P           G  G +GPT                  
Sbjct: 468 -PGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIA 526

Query: 165 --GAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGK 221
             G PGP G  G  G  G PG +G KGE   G PG  G RG+ GP GPTG  G  G  G 
Sbjct: 527 LRGPPGPMGLTGRPGPVGGPGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGA 584

Query: 222 RGENGVPGQPGIKGDRGFP------------GEMGPIGPPGPQGPPGERGPEG----IGK 265
            G  G+PG+PG KGDRGF             GE GP GPPGP G  G RG +G     G 
Sbjct: 585 DGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGL 644

Query: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------FGKPGLPGLKGERGPAGLP-- 316
           PG AG  G  G  GT G PG PG+AG  GPPG        G+PG PG +G  GP GLP  
Sbjct: 645 PGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 704

Query: 317 ----GGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372
               G PG KG QG  GL G PG  GPPG+ G +G  G  G+ G PGP+G  G  GP G 
Sbjct: 705 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764

Query: 373 PGA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGP 426
            GA      KG +G  G DG PG+ G  GL G +G  G  GP+G+ G  GP G  GP G 
Sbjct: 765 KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824

Query: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------PGP------ 474
            G  G  G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+      PGP      
Sbjct: 825 PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884

Query: 475 ---------------PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQA 519
                          PGP G  T G +GP GPPG  GP+G  G  G PGP GPPGPPG+ 
Sbjct: 885 TGPRGSRGARGPTGKPGPKG--TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD 942

Query: 520 VMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            +P      GQR         +  QG TG P
Sbjct: 943 GLPG---HPGQRGE-------TGFQGKTGPP 963



 Score =  292 bits (748), Expect = 6e-79
 Identities = 186/486 (38%), Positives = 224/486 (46%), Gaps = 92/486 (18%)

Query: 137 PRGPPGP---PGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193
           P  PP     PG+P    I+     G        G  G  G+KG P V     + G +  
Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGH-------GAYGEKGQKGEPAVV----EPGMLVE 441

Query: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPI------- 246
           G PG  G  G+ GP G  GP+GPPG    G+ G PG+PG+ G  G PG  G +       
Sbjct: 442 GPPGPAGPAGIMGPPGLQGPTGPPG--DPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRY 499

Query: 247 -----------------------------GPPGPQGPPGERGPEGIGKPGAAGAPGQPGI 277
                                        GPPGP G  G  GP  +G PG++GA G+ G 
Sbjct: 500 GGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGD 557

Query: 278 PGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLT 337
           PG +G     G+ GPPGP G  KPG  G  G  G  G+PG PGAKG++G  GLPG PG  
Sbjct: 558 PGPQG---PRGVQGPPGPTG--KPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDK 612

Query: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
           G  G  GPQGP G PG  G+ G  GE GP G  G  G +G  G  G+ G PG PG  G+D
Sbjct: 613 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVD 672

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPP 457
           GP G  G  GP+G+PG  G  G PGP G  G +G  G  GE GP+G PG+ G  G  GPP
Sbjct: 673 GPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732

Query: 458 GIPGFPGSKGDPGSPGPPGPAG----IATKGLNGPTGPPGPPGPRGHSGEPGLP------ 507
           G PG  G  G+ G+ GPPGP G       +G+ G  G  G  G +G  GE G P      
Sbjct: 733 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792

Query: 508 ------------------GPPGPPGPPGQAVMPEGFIKAGQR-----PSLSGTPLVSANQ 544
                             GP GP G  G    P    +AG++     P L G P     +
Sbjct: 793 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852

Query: 545 GVTGMP 550
           G TG P
Sbjct: 853 GSTGFP 858



 Score =  224 bits (570), Expect = 3e-58
 Identities = 141/343 (41%), Positives = 161/343 (46%), Gaps = 84/343 (24%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKP---- 108
            G  G PGP GP GP G  GP GPPG  G     G  G  GE G PGPPG + VG P    
Sbjct: 1219 GPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGER 1278

Query: 109  ------GVPGLPGKPGERGPYG---PKGDVGPAGLPGPRGPPGPPGIPGPAGISV----- 154
                  G PG  G PG +GP G   PKG+ GP G PG  GPPG PG  G  G+       
Sbjct: 1279 GEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGED 1338

Query: 155  --PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPGPQ 208
              PG+PG  GP+G  GP G PG++G PG  G  G++GE G     GA G PG+ G  GPQ
Sbjct: 1339 GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQ 1398

Query: 209  GPTGPSGPPGV----GKRGENGVPG---------------------QPGIKGDRGFPGEM 243
            GP G  GP G+    G  GE G+PG                      PG KG++G PG +
Sbjct: 1399 GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLI 1458

Query: 244  GPIGPPGPQGPPGERGPEGI-GKPGAAG------------APGQPGIPGTKG-------- 282
            G IGPPG QG  G+RG  G  G PGA G             PG PG+PG +G        
Sbjct: 1459 GLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518

Query: 283  ----------LPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL 315
                      LPG PG  GPPG      P L   K  R   G+
Sbjct: 1519 GPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEGM 1561



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 39/113 (34%), Positives = 48/113 (42%), Gaps = 8/113 (7%)

Query: 445 PGIPG----TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGH 500
           PG+P     T   I   G  G  G KG+P    P    G+  +G  GP GP G  GP G 
Sbjct: 403 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPAGPAGIMGPPGL 458

Query: 501 SGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSA 553
            G  G PG PG  GPPG+  +P      G   ++   P      G  G  +SA
Sbjct: 459 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISA 511



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 37/92 (40%), Positives = 42/92 (45%), Gaps = 9/92 (9%)

Query: 44   IPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG---PSGPPGKPGYGSP----GLQGEPGL 96
            +P T  S G   +G+ G PGP GP GP G PG   P GP G  G   P    G  G PG 
Sbjct: 1475 LPGTQGSPG--AKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP 1532

Query: 97   PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGD 128
            PG PGP       +P L  K   R   G + D
Sbjct: 1533 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQAD 1564


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  434 bits (1115), Expect = e-121
 Identities = 253/566 (44%), Positives = 284/566 (50%), Gaps = 77/566 (13%)

Query: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPG-------YGSPGLQGEPGLPGPPGPSAV---- 105
           G  G+ G  GP GP G  GP GP G PG        G+PG +G  G+PG PGP       
Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIP 374

Query: 106 GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG-PAGISVPGKPGQQGPT 164
           G  G PG PG  GE GP G +G  GP G  G  GPPGP G PG P  I   G PG +GPT
Sbjct: 375 GSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPT 434

Query: 165 GAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPG---------ERGLPGPQGPTGPS 214
           G+PG  G PG  G PG PG  G  G  G  G PG PG          +G PGP G  GP 
Sbjct: 435 GSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPI 494

Query: 215 GPPGV----GKRGENGVPGQPGIKGDRGFPGEMG---PIGPPGPQGPPGERGPEGIGKPG 267
           GPPG     G RG+ G  G PG  G+RG PG  G     G PGP+G  GERGP  +G  G
Sbjct: 495 GPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP--VGSSG 552

Query: 268 AAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQG 326
             G+ G PG PG  GLPGA G+ G PG  G  GK G  G  GE G  G PG  G +G+ G
Sbjct: 553 PKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG 612

Query: 327 PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDG 386
             GLPG  G +G PG  G  G  G+PG  G PG  GE GP+GP G PG  GERG  G  G
Sbjct: 613 SMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG 672

Query: 387 KPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEA------- 439
             G+ G PG  GP G  G P   GD GV G PG  GP+GP G +G PG  GE        
Sbjct: 673 PTGFQGLPGPPGPPGEGGKP---GDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPG 729

Query: 440 -----------GPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG--------- 479
                      GP+G+PG  GT G  GPPG+ G PG +G  G+PGP G  G         
Sbjct: 730 EKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEG 789

Query: 480 ----IATKGLNGPTGPPGPPGPRGHSGEP---GLPGPPGPPGPPGQ--------AVMPEG 524
                  +GL GP GPPGP GP G  GEP   GL GPPG  G PG         AV   G
Sbjct: 790 TAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849

Query: 525 FIKAGQRPSLSGTPLVSANQGVTGMP 550
                 +P + G P     +G  G P
Sbjct: 850 PQGPDGQPGVKGEPGEPGQKGDAGSP 875



 Score =  432 bits (1110), Expect = e-121
 Identities = 270/643 (41%), Positives = 307/643 (47%), Gaps = 149/643 (23%)

Query: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPG-PSAVGKPGVPG 112
           V G +G PGP GP G +G  G  GP G+PG  G  G+ GEPG+PG PG P   G P  PG
Sbjct: 124 VTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPG 183

Query: 113 ---------------------------LPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG 145
                                      +PG  G  GP GP+G  G  G  GP GPPG PG
Sbjct: 184 PDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPG 243

Query: 146 IPGPAG-------ISVPGKPGQQGP------------TGAPGPRGFPGEKGAPGVPGMNG 186
            PGP G          PGKPG+ G              G+PG RGFPG  G PG+ G  G
Sbjct: 244 DPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRG 303

Query: 187 QKGEMG----YGAPGRPGERGLPGPQGPTGPSGPPGV-------------GKRGENGVPG 229
            KG  G     GAPG  GE G  GP G  GP GP G+             G+RG +G+PG
Sbjct: 304 HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPG 363

Query: 230 QP------GIKGDRGFP------GEMGPIGPPGPQGPPGERGPEG----IGKPGAAGAPG 273
           +P      GI G  GFP      GE GP G  GP+GP G+RG  G    +G PG  GA G
Sbjct: 364 KPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIG 423

Query: 274 QPGIPGTKGLPGAPGIAGPP---GPPGF----------------GKPGLPGLKGERGPAG 314
             G PG KG  G+PG +GPP   GPPG                 G PG+PG KGE GP G
Sbjct: 424 TDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKG 483

Query: 315 LPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---------KGIPGSHGLPGPKGETG 365
            PG  G +G  GP G  GK G  G PG +GP GP         +G PGS GLPGPKG  G
Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543

Query: 366 PAGPAGYPGAKGERGSPGSDGKPGYP------GKPGLDGPK---------GNPGLPGPKG 410
             GP G  G KG +G PG  G+PG P      G PG+ GP+         G  G PGP G
Sbjct: 544 ERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603

Query: 411 DPGVGGPP---GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKG 467
             G+ G P   GLPGP G +G  G PG  G AG  G  G PG  G +GP G  G PG  G
Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663

Query: 468 DPGSPGPPGPAGIATKGLNGPTGPP------------------GPPGPRGHSGEPGLPGP 509
           + G  GPPGP G   +GL GP GPP                  GP GPRG  G PG  G 
Sbjct: 664 ERGEQGPPGPTGF--QGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGE 721

Query: 510 PGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMP 550
           PG  G PG+  M  G    G +  P  SGTP  +   G+ GMP
Sbjct: 722 PGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMP 764



 Score =  431 bits (1108), Expect = e-120
 Identities = 262/576 (45%), Positives = 293/576 (50%), Gaps = 108/576 (18%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV-------GKP 108
            GE+G  GPPGP G +G PGP GPPG+ G  G  G+ G+PG  GP GP          G+P
Sbjct: 663  GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEP 722

Query: 109  GVPGLPGKPGE---RGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVP---------- 155
            G+ GLPG+ G     GP GPKG  GP+G PG  GPPG  G+PG  GI+            
Sbjct: 723  GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782

Query: 156  GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPS 214
            G+ G +G  G  G RG PG  G PG  G  G+KGE G  G  G PG RG PG +G  GP+
Sbjct: 783  GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842

Query: 215  GPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG---PPGERGPEGI-------- 263
            G   VG  G  G  GQPG+KG+ G PG+ G  G PGPQG    PG  GP G+        
Sbjct: 843  G--AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG 900

Query: 264  --GKPGAAGAPGQPGIPGTKGLPGAPGIAGP------PGPPGF-GKPGLPGLKGERGPAG 314
              G PGA G PG  G  G  G  GAPG AGP       GPPG  G PG  G  G+RGPAG
Sbjct: 901  TQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960

Query: 315  LPGGPGAKGEQG---------------------------------------PAGLPGKPG 335
             PGGPG KG+ G                                       PAG PGK G
Sbjct: 961  PPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG 1020

Query: 336  LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGA------KGERGSPGSDGKPG 389
             TG  G+ GP GP G PGS+G  G  G  GPAG  G PG       +G+RG PG  G PG
Sbjct: 1021 PTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080

Query: 390  YPGKPGLDGPKGNPGLPGPKGDPGVGGP---------PGLPGPVGPAGAKGMPGHNGEAG 440
              G PG  GP G PG  G +GDPG  GP          GLPGP GP G KG  G  G+ G
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRG 1140

Query: 441  PRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS---PGPPGPAGIATK-GLNGPTGPPGPPG 496
             +G  G  G +G  GPPG  G  GS G PG     GPPGP G + K G  GP GP GPPG
Sbjct: 1141 QKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPG 1200

Query: 497  PRGHSGE------PGLPGPPGPPGPPGQAVMPEGFI 526
             RG  GE      PG PGPPGPPGPPG      G I
Sbjct: 1201 VRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDI 1236



 Score =  429 bits (1103), Expect = e-120
 Identities = 256/542 (47%), Positives = 278/542 (51%), Gaps = 62/542 (11%)

Query: 57   GEQGTPGPPGPAGPRGHPGP---------SGPPGKPGY-GSPGLQGEPGLPGPPGPSAVG 106
            GE G PGPPG  G RG PG          SG PGKPG  G+ G+ G+ G PG  G   VG
Sbjct: 594  GEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGE--VG 651

Query: 107  KPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGA 166
              G  G PG  GERG  GP G  G  GLPGP GPPG  G PG  G  VPG PG  GP G 
Sbjct: 652  PSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQG--VPGDPGAVGPLGP 709

Query: 167  PGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGV-GKRGEN 225
             G RG PGE+G PG+ G+ G+KG  G   P  P  +G PGP G  G +GPPG+ G  GE 
Sbjct: 710  RGERGNPGERGEPGITGLPGEKGMAGGHGPDGP--KGSPGPSGTPGDTGPPGLQGMPGER 767

Query: 226  GVPGQPGIKGDRGFPGEMG---------------PIGPPGPQGPPGERGPEGI-GKPGAA 269
            G+ G PG KGDRG  GE G               P+GPPGP GP GE+G  G  G  G  
Sbjct: 768  GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827

Query: 270  GAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
            G+ G PG  G  G  GA G AGP GP G  G  G PG  G++G AG PG  G  G  GP 
Sbjct: 828  GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPH 887

Query: 329  GLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKP 388
            G  G PGL G  G  GP G  G PGS G  GP G  G  GPAG  G  G+ G PG  G P
Sbjct: 888  GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP 947

Query: 389  GYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP 448
            G  G+ G  GP G PG PG KGDPG  G PG  GP GPAG  G  G  G  G RG  G+P
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007

Query: 449  GTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEP---- 504
            G  GP G PG  G  G+ GD G PGP GP      G NGP G PGP GP G+ G P    
Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGPPGPVGP-----PGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 505  --------------GLPGPPGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTG 548
                          GLPG  G PG PG    P     AGQR  P   G        G  G
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG---DAGQRGDPGSRGPIGPPGRAGKRG 1119

Query: 549  MP 550
            +P
Sbjct: 1120 LP 1121



 Score =  422 bits (1085), Expect = e-118
 Identities = 260/570 (45%), Positives = 286/570 (50%), Gaps = 89/570 (15%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGP---PGKPG-------YGSPGLQGEPGLPGPPG----- 101
            G  G  GPPG AG RG  GP GP    G PG        G PG QG PG PG  G     
Sbjct: 651  GPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPR 710

Query: 102  -----PSAVGKPGVPGLPGK---PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGIS 153
                 P   G+PG+ GLPG+    G  GP GPKG  GP+G PG  GPPG  G+PG  GI+
Sbjct: 711  GERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIA 770

Query: 154  VP----------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGER 202
                        G+ G +G  G  G RG PG  G PG  G  G+KGE G  G  G PG R
Sbjct: 771  GTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSR 830

Query: 203  GLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG 262
            G PG +G  GP+G   VG  G  G  GQPG+KG+ G PG+ G  G PGPQG  G  GP G
Sbjct: 831  GNPGSRGENGPTG--AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888

Query: 263  -IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLP-GLKGERGPAGLPGGPG 320
              G PG  G  G  G PG  G PG+ G  GPPGP G   P  P G  G+ GP GL G PG
Sbjct: 889  PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPG 948

Query: 321  AK---GEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKG 377
            +    G++GPAG PG PG  G PG        G PG  G PGP G TG  G  G PG +G
Sbjct: 949  SHGRVGDRGPAGPPGGPGDKGDPGE------DGQPGPDGPPGPAGTTGQRGIVGMPGQRG 1002

Query: 378  ERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHN- 436
            ERG PG  G  G PGK G  G  G+ G PGP G PG  GP G PGP GPAG  G PG + 
Sbjct: 1003 ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 437  --------GEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-GLNG 487
                    G+ GP G PG  G  G  GP G PG  G +GDPGS GP GP G A K GL G
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPG 1122

Query: 488  PTGP---------------------------PGPPGPRGHSGEPGLPGPPGPPGPPGQAV 520
            P GP                           PGPPGP G  G  G+PGP GP GPPG  V
Sbjct: 1123 PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPG-PV 1181

Query: 521  MPEGFIKAGQRPSLS--GTPLVSANQGVTG 548
             P G  K G    L   G P V  + G  G
Sbjct: 1182 GPSG--KEGNPGPLGPIGPPGVRGSVGEAG 1209



 Score =  375 bits (963), Expect = e-104
 Identities = 236/551 (42%), Positives = 269/551 (48%), Gaps = 87/551 (15%)

Query: 64  PPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPY 123
           PPG   P     P G     G G  G +GEPGL           P V G+ G+PG   P 
Sbjct: 88  PPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLV----------PVVTGIRGRPG---PA 134

Query: 124 GPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPG 183
           GP G  GP G  GP+G PGP G   P GI   G+PG  G  GAPGP G P   G  G+  
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRG---PQGID--GEPGVPGQPGAPGPPGHPSHPGPDGLSR 189

Query: 184 -----MNGQKGEMGYGAPGRPGERGL-PGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDR 237
                M G   + G G+     + GL PG  GP GP GP G+  +G+ G  G  G  G+ 
Sbjct: 190 PFSAQMAGLDEKSGLGS-----QVGLMPGSVGPVGPRGPQGL--QGQQGGAGPTGPPGEP 242

Query: 238 GFPGEMGPIGPPGPQGPPGERGPEG-------------IGKPGAAGAPGQPGIPGTKGLP 284
           G PG MGPIG  GP+GPPG+ G +G              G PGA G PG PG+PG KG  
Sbjct: 243 GDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHR 302

Query: 285 GAPGIAGPPG----PPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPP 340
           G  G+ GP G    P   G+ G  G  G  GP G  G PG +G  GP G PG+ G  G P
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362

Query: 341 GNMGPQGPKGIPGSHGLPGP---KGETGPAG---PAGYPGAKGERGSPGSDGKPGYPGKP 394
           G  GP GP GIPGS G PG    KGE GP G   P G  G +GE G PG  G PG PG  
Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422

Query: 395 GLDGP---KGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGM---------PGHNGEAGPR 442
           G DG    KG  G PG  G PG  GPPG PGP G  G +G+         PG  GEAGP+
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 443 GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG----------------IATKGLN 486
           G PG  G +GPIGPPG  G  G +GDPG+ GPPGP G                   KG  
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 487 GPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG-----QAVMPEGFIKAGQRPSLSGTPLVS 541
           G  GP G  GP+G  G+PG PG PG PG  G         PEG +     P   G P   
Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602

Query: 542 ANQGVTGMPVS 552
            + G+ G P S
Sbjct: 603 GSIGIRGQPGS 613



 Score =  313 bits (801), Expect = 4e-85
 Identities = 185/402 (46%), Positives = 215/402 (53%), Gaps = 33/402 (8%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPG-KPGYGSPGLQGEPGLP------GPPGPSAVGKP 108
            +G+ G+PGP G AG  G  GP+G PG K G G+ G  G  G P      GPPGP+  G P
Sbjct: 869  KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPA--GAP 926

Query: 109  GVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168
            G  G  G+PG+ GP G +GD G  G  G RGP GPPG PG  G   PG+ GQ GP G PG
Sbjct: 927  GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG--DPGEDGQPGPDGPPG 984

Query: 169  PRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGKRGENGV 227
            P G  G++G  G+PG  G++G    G PG  G  G  GP G TG  GPPG VG  G NG 
Sbjct: 985  PAGTTGQRGIVGMPGQRGERGMP--GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042

Query: 228  PGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGA 286
             G+PG +G  G  G  G  G  G +G  G+ GP G+ G  GA G PG  G PG  G  G 
Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD 1102

Query: 287  PGIAGPPGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGP 345
            PG  GP GPPG  GK GLPG +G RG  G  G  G +G++G  G  G  GL GPPG  G 
Sbjct: 1103 PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE 1162

Query: 346  QGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGL 405
            QG  GIPG  G  GP G  GP+G  G PG  G  G P               G +G+ G 
Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPP---------------GVRGSVGE 1207

Query: 406  PGPKGDPGVGGPPGLPGPVG--PAGAKGMPGHNGEAGPRGAP 445
             GP+G PG  GPPG PGP G   A    + GH  E+ P   P
Sbjct: 1208 AGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLP 1249



 Score =  137 bits (345), Expect = 3e-32
 Identities = 86/204 (42%), Positives = 99/204 (48%), Gaps = 24/204 (11%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPG 89
            G +GP  N  T        +   +  RG++G PGP G  G +G PG  GP G P  G  G
Sbjct: 1047 GPEGPAGNDGTPG------RDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAP--GDAG 1098

Query: 90   LQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGP 149
             +G+PG  GP GP   G+ G  GLPG  G RG  G  GD G  G  G RG  G  G+PGP
Sbjct: 1099 QRGDPGSRGPIGPP--GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGP 1156

Query: 150  AGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQ 208
                 PG  G+QG  G PGP G  G  G  G  G  G  G +G  G PG  G  G  GP+
Sbjct: 1157 -----PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPE 1211

Query: 209  GPTGPSGPPGVGKRGENGVPGQPG 232
            GP G  GPP        G PG PG
Sbjct: 1212 GPPGEPGPP--------GPPGPPG 1227


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  431 bits (1108), Expect = e-120
 Identities = 240/504 (47%), Positives = 285/504 (56%), Gaps = 25/504 (4%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGL-PGPPGPSAVGKPGVPGLP 114
            G  G PG PG  GPRG PGP G PG PG  G+ G +G+PGL PG     A G  G+PGL 
Sbjct: 640  GLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLS 699

Query: 115  GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPG 174
            G PG  G  G KG  GPAG PG +G PGP G PG  G   PG+ G  GP G PGP+G  G
Sbjct: 700  GNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGY--PGRQGLPGPVGDPGPKGSRG 757

Query: 175  EKGAPGVPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPG 232
              G PG+ G+ G  GE G  G PG+ G+ G+PG  G  G  GPPG+ G  GE G+PG PG
Sbjct: 758  YIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPG 817

Query: 233  IKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGP 292
            + G  G  G +GPIG PGP+G  G  G   +G+PG  G  G+ G+PG  G PG  G  G 
Sbjct: 818  VPGLIGDLGVLGPIGYPGPKGMKGLMG--SVGEPGLKGDKGEQGVPGVSGDPGFQGDKGS 875

Query: 293  PGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIP 352
             G PGF     PG +G+ GP G  G  G+ G  GP G  G PG  GPPG+ GP+G KG P
Sbjct: 876  QGLPGF-----PGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKP 930

Query: 353  GSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDP 412
            G+ GLPGP+G+ GP G  G  G  G  G  G  G+ G+PG+PGLDG KG PG P   G P
Sbjct: 931  GARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP---GRP 987

Query: 413  GVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472
            G  G  G  G +G  G  G+ G  G+ G  G PG+PG +G +G PG+PG  G+ G+PG  
Sbjct: 988  GPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQ 1047

Query: 473  GPPGPAG-IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531
            GPPG  G    +G  G  GP GP GP G  G  GL GPPGP G PG+   P     AG+R
Sbjct: 1048 GPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGR---PGQQGVAGER 1104

Query: 532  PSLS-----GTPLVSANQGVTGMP 550
              L      G P  S   G  G+P
Sbjct: 1105 GHLGSRGFPGIPGPSGPPGTKGLP 1128



 Score =  428 bits (1100), Expect = e-120
 Identities = 260/614 (42%), Positives = 308/614 (50%), Gaps = 98/614 (15%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKG-------IAVRGEQGTPGPPGPAGPRGHPGPSGPPGK 82
            G+ GP P  K Q   P     K        + + G  G PGPPG  G +G+PGP+G PG+
Sbjct: 664  GLPGP-PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGE 722

Query: 83   PGY----GSPGLQGEPG---LPGP---PGPSA----VGKPGVPGLPGKPGERG---PYGP 125
             G     GSPG +G PG   LPGP   PGP      +G PG+ GLPG  GERG     G 
Sbjct: 723  QGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGK 782

Query: 126  KGDVGPAGLPGPRGPPGPPGIPG-PAGISVPGKPGQQG---------PTGAPGPRGFPGE 175
            +G +G  G PG  G  GPPG+ G P  + +PG PG  G         P G PGP+G  G 
Sbjct: 783  RGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGL 842

Query: 176  KGAPGVPGMNGQKGEMGY----------------GAPGRPGERGLPGP------------ 207
             G+ G PG+ G KGE G                 G PG PG RG PGP            
Sbjct: 843  MGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGF 902

Query: 208  QGPTGPSGPPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GK 265
             GP GP G PG +G  G+NG  G  G  G RG PG  G +GP G +GP G  G  G+ G+
Sbjct: 903  PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQ 962

Query: 266  PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-------GKPGLPGLKGERGPAGLPGG 318
            PG  G PG+PG+ G KG PG PG  GP G  GF       G+PG+ G KG+RG  G PG 
Sbjct: 963  PGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGV 1022

Query: 319  PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
            PG KG  G  G+PG  G  G PG  GP G +G PG  G  G +G  GP GPAG  G++G 
Sbjct: 1023 PGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGL 1082

Query: 379  RGSPGSDGKPGYPGK---------------PGLDGPKGNPGLPGPKGDPGVGGPPGLPGP 423
            +G PG  G+PG PG+               PG+ GP G PG  G  G+PG  GP G  GP
Sbjct: 1083 KGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGP 1142

Query: 424  VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK 483
             G  G KG PG  GE G  G  G+ G  GP+G PG  G  G +G+PG  G  GP G    
Sbjct: 1143 PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG--PD 1200

Query: 484  GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVM--PEGFIKAGQ-----RPSLSG 536
            GL G  G PGP G  G  G+ GL G  GPPGPPG   +  PEG  K+G+     R    G
Sbjct: 1201 GLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEG--KSGKQGEKGRTGAKG 1258

Query: 537  TPLVSANQGVTGMP 550
                    G  G+P
Sbjct: 1259 AKGYQGQLGEMGVP 1272



 Score =  403 bits (1036), Expect = e-112
 Identities = 238/557 (42%), Positives = 288/557 (51%), Gaps = 73/557 (13%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAVGKPGV 110
            V+GE G PG PGP G +G  G  G  G+PG     G  G+ G PG+PGP G  ++G PG+
Sbjct: 977  VKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG--SMGHPGM 1034

Query: 111  PGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPR 170
            PG  G PGE GP GP G  GP G+ G +G  GP G  GPAG     + G +G  G PGP+
Sbjct: 1035 PGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAG-----EQGSRGLKGPPGPQ 1089

Query: 171  GFPGEKGAPGVPGMNGQKGEMGY----GAPGRPGERGLPG---PQGPTGPSGPPG-VGKR 222
            G PG  G  GV G  G  G  G+    G  G PG +GLPG   PQGP GP GPPG +G +
Sbjct: 1090 GRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPK 1149

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI----------GKPGAAGAP 272
            G  G  G+PG+ G+ G  G++GP+G PG QG  G+RG  G+          G  G  G P
Sbjct: 1150 GPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP 1209

Query: 273  GQPGIPGTKGLPGAPGIAGPPGPPGF----------------------------GKPGLP 304
            G  G  G KG  G  G  GPPGPPG                             G+ G  
Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 305  GLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGET 364
            G+ G+ GP G PG  G++G  GP G PG+ G  G PG  G  G KGI G  G PGPKGE 
Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEK 1329

Query: 365  GPAG-------PAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGP 417
            G  G       P G PG +G  G  G  G+PG PG PG +G +G  G PG +G PG  GP
Sbjct: 1330 GEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389

Query: 418  PGLPGPVGPAGAKGMPGHNGEAGP------RGAPGIPGTRGPIGPPGIPGFPGSKGDPGS 471
             G PGP G  GA+G  G  G+AG       +G  G+PG RG +G  G+ G  G  G PG 
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449

Query: 472  PGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531
             G  G  G   +G +G  GP GP G RG+ G  GLPG  GPPG  G++ +P      G+R
Sbjct: 1450 DGQAGQQG--EQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKR 1507

Query: 532  PSLSGTPLVSANQGVTG 548
             +   T L   NQG  G
Sbjct: 1508 GTEGRTGL-PGNQGEPG 1523



 Score =  400 bits (1029), Expect = e-111
 Identities = 242/568 (42%), Positives = 290/568 (51%), Gaps = 110/568 (19%)

Query: 55   VRGEQGTPGPPGPAGP---------RGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPG 101
            +RG +G  GP GP GP         +G PGP G PG+PG     G  G  G  G PG PG
Sbjct: 1058 MRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117

Query: 102  PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP---PGIPGPAGISVPGKP 158
            PS  G PG  GLPG+PG +GP GP   +GP G  GP+GPPG    PG+PG AG+      
Sbjct: 1118 PS--GPPGTKGLPGEPGPQGPQGP---IGPPGEMGPKGPPGAVGEPGLPGEAGMK----- 1167

Query: 159  GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-------GAPGRPGERGLPGPQGPT 211
            G  GP G PG +G  G++G PG+ G +G  G  G        G  G  GE+G  G  G  
Sbjct: 1168 GDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGED 1227

Query: 212  GPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-- 262
            GP GPPGV       GK G+ G  G+ G KG +G+ G++G +G PG  GPPG  GP+G  
Sbjct: 1228 GPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSR 1287

Query: 263  -----IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-----------GKPGLPGL 306
                  G PG  GA G+PG+ G  G  G  G  GPPGP G            G PG PG 
Sbjct: 1288 GSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGD 1347

Query: 307  KG---ERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGP------------QGPKG- 350
            +G   +RG  G PG PG  G++G  GL GKPG  G PG+ GP            +GPKG 
Sbjct: 1348 RGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK 1407

Query: 351  -----------IPGSHGLPGPKGETGP------AGPAGYPGAKGERGSPGSDGKPGYPGK 393
                       + G  GLPGP+G  G       AGP G PG  G+ G  G  G  G PG 
Sbjct: 1408 QGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGP 1467

Query: 394  PGLDGPKGNPG---LPGPKGDPGVGGPPGLPGPVGPAGAKG------MPGHNGEAGPRGA 444
             G  G +GNPG   LPG +G PG  G  GLPG +GP G +G      +PG+ GE G +G 
Sbjct: 1468 MGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQ 1527

Query: 445  PG------IPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG----IATKGLNGPTGPPGP 494
            PG       PG  G  GP G PG  G KG  G  GPPG  G    +   G+ GP+G PGP
Sbjct: 1528 PGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGP 1587

Query: 495  PGPRGHSGEPGLPGPPGPPGPPGQAVMP 522
             G +G  G+ GL GP GPPGP G+   P
Sbjct: 1588 KGDKGSRGDWGLQGPRGPPGPRGRPGPP 1615



 Score =  265 bits (678), Expect = 8e-71
 Identities = 164/358 (45%), Positives = 187/358 (52%), Gaps = 42/358 (11%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPG------PPGPSAV 105
            + V G+ G PG PGP G RG  GP+G PG+ G  G PGL G  G  G      PPGP   
Sbjct: 1269 MGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGE 1328

Query: 106  ----GKPG-VPGLPGKPGERGPYGPKGDVGPAGLPG------------------PRGPPG 142
                G+ G   G PG PG+RGP G +GD G  G PG                    G PG
Sbjct: 1329 KGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPG 1388

Query: 143  PPGIPGPAGI-SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAPG 197
            P G PGP G     G  G+QG  GAPG RG  G +G PG  G+ G++G  G     G PG
Sbjct: 1389 PRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPG 1448

Query: 198  RPGERGLPGPQGPTGPSGPPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPG 256
            R G+ G  G QG  G  GP G  GKRG  GV G PG +G  GF GE    G PG  GPPG
Sbjct: 1449 RDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGES---GLPGQLGPPG 1505

Query: 257  ERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGL 315
            +RG EG  G PG  G PG  G PG  G  G PG+AG  GP   G PG  G KG +GP G 
Sbjct: 1506 KRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPK--GPPGDIGFKGIQGPRGP 1563

Query: 316  PGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYP 373
            PG  G +G  GP G+ G  GL GP G+ G +G  G+ G  G PGP+G  GP GP G P
Sbjct: 1564 PGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  225 bits (574), Expect = 9e-59
 Identities = 194/573 (33%), Positives = 230/573 (40%), Gaps = 101/573 (17%)

Query: 31  IKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGL 90
           IK P P  KT    P +     +  + +      P PA        S P  KP      +
Sbjct: 382 IKSPHPTQKTA---PSSFTKSALPTQKQVPPTSRPVPARV------SRPAEKP------I 426

Query: 91  QGEPGLPGPPGPS--------AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPG 142
           Q  PG+P PP PS        +  K  +P L     +   +  K    PA        P 
Sbjct: 427 QRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASK----PASARTSTHKPP 482

Query: 143 PPGIPGPAGISVPGKPGQQGP--TGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPG 200
           P      +    PG      P  T  P   G    + AP VP                PG
Sbjct: 483 PFTALSSSPAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVP---------------TPG 527

Query: 201 ERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGP 260
                 P G   P G     K G    P +P +    G      P+     +  P +  P
Sbjct: 528 S----APTGSKKPIGSEASKKAGPKSSPRKP-VPLRPGKAARDVPLSDLTTRPSPRQPQP 582

Query: 261 EGIGKPGAAGAPGQ-------PGIPGTK-----GLPGAPGIAGPPGPPG-FGKPGLPGLK 307
                P    AP Q       P   G       G    P + GPPGP G  G PG PGL 
Sbjct: 583 SQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLP 642

Query: 308 GERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG---------------NMGPQGPKGIP 352
           G      LPG PGA+G +GP G  G PGL GPPG               + G +G  G+P
Sbjct: 643 G------LPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLP 696

Query: 353 GSHGLPGP---KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNP------ 403
           G  G PGP   KG  G  GPAG+PG +G+ G  GS G  GYPG+ GL GP G+P      
Sbjct: 697 GLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSR 756

Query: 404 ---GLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP 460
              GLPG  G PG  G  GLPG  G  G  GMPG  G  G RG PG+ G  G +G PG P
Sbjct: 757 GYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPP 816

Query: 461 GFPGSKGDPGSPGP---PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG 517
           G PG  GD G  GP   PGP G+  KGL G  G PG  G +G  G PG+ G PG  G  G
Sbjct: 817 GVPGLIGDLGVLGPIGYPGPKGM--KGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKG 874

Query: 518 QAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
              +P GF  A  +P   G      + G  G P
Sbjct: 875 SQGLP-GFPGARGKPGPLGKVGDKGSIGFPGPP 906



 Score =  178 bits (451), Expect = 2e-44
 Identities = 178/584 (30%), Positives = 210/584 (35%), Gaps = 133/584 (22%)

Query: 96  LPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLP---------------GPRGP 140
           LP   GP     P  P  P +     P+      GPA  P                P   
Sbjct: 282 LPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASV 341

Query: 141 PGPPGIPGPAGI-------------SVPGKPGQQGPTGAPGPRGFPGEKGAPG---VPGM 184
            G    P PA               S+P KP     +  P     P +K AP       +
Sbjct: 342 GGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSAL 401

Query: 185 NGQKGEMGYGAP-----GRPGER------GLPGPQGP----------------------- 210
             QK       P      RP E+      G+P P  P                       
Sbjct: 402 PTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTE 461

Query: 211 ---TGPSGPPGVGKRGENGVPGQPGIKGDRG-FPGEMGPIGPPGPQGPPGERGPEGIGKP 266
              T  +  P   +   +  P    +       PG      PP    PP      G   P
Sbjct: 462 AKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPP----TSGTSTP 517

Query: 267 GAAGAPGQPGI--PGTKGLPG--APGIAGPPGPPGFGKPGLPGLKGERGPAG------LP 316
             A A   PG    G+K   G  A   AGP   P    P  PG      P         P
Sbjct: 518 RTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSP 577

Query: 317 GGPGAKGEQGP--------------------------AGLPGKPGLTGPP---GNMGPQG 347
             P    +  P                          AG    P L GPP   G+ G  G
Sbjct: 578 RQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLPG 637

Query: 348 PKGIPGSHGLPGPKGETGPAGP------AGYPGAKGERGSPG------SDGKPGYPGKPG 395
           P G+PG  G+PG +G  GP GP       G PGAKG++G PG       DG  G  G PG
Sbjct: 638 PPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPG 697

Query: 396 LDGPKGNPGLPGPKGDPGVGGPP---GLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG 452
           L G  G PG  G KG PG  G P   G PGP G  GAKG PG  G  GP G PG  G+RG
Sbjct: 698 LSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRG 757

Query: 453 PIGPPGIPGFPGSKGDPGSPGPPGPAG-IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPG 511
            IG PG+ G PGS G+ G PG PG  G +   G  G  G  GPPG  G+ GE GLPGPPG
Sbjct: 758 YIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPG 817

Query: 512 PPGPPGQ--AVMPEGFIKAGQRPSLSGT---PLVSANQGVTGMP 550
            PG  G    + P G+        L G+   P +  ++G  G+P
Sbjct: 818 VPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVP 861



 Score =  169 bits (428), Expect = 8e-42
 Identities = 104/254 (40%), Positives = 128/254 (50%), Gaps = 48/254 (18%)

Query: 57   GEQGTPGPPGPAG---PRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV------- 105
            G+QG PG PGP G   P+G  G  GP GK G  G+PG +G  GL G PGP  V       
Sbjct: 1379 GQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLE 1438

Query: 106  ---GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG-------------P 149
               G  G+PG  G+ G++G  G  GD GP G  G RG PG  G+PG             P
Sbjct: 1439 GIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLP 1498

Query: 150  AGISVPGKPGQQGPTGAPGPRGFPGEKGAPG------VPGM------NGQKGEMGY---- 193
              +  PGK G +G TG PG +G PG KG PG       PGM       G  G++G+    
Sbjct: 1499 GQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQ 1558

Query: 194  ---GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG 250
               G PG  G+ G+ GP G  GPSG PG   +G+ G  G  G++G RG PG  G  GPPG
Sbjct: 1559 GPRGPPGLMGKEGIVGPLGILGPSGLPG--PKGDKGSRGDWGLQGPRGPPGPRGRPGPPG 1616

Query: 251  PQGPPGERGPEGIG 264
            P G P +   + +G
Sbjct: 1617 PPGGPIQLQQDDLG 1630


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  429 bits (1103), Expect = e-120
 Identities = 272/649 (41%), Positives = 309/649 (47%), Gaps = 130/649 (20%)

Query: 26   QMPTGIKGPL--PNTKTQFFIPYTIKSKG-IAVRGEQGTPGPPGPAGP------------ 70
            Q P G  GP   P    +  +P     +G +  +G+ G PGPPG  GP            
Sbjct: 796  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 855

Query: 71   RGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV 129
            RGHPGP GPPG+ G  G+ G +G  G PGPPG  A GK G  GL G PGERG  G  G  
Sbjct: 856  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG--APGKDGPAGLRGFPGERGLPGTAGGP 913

Query: 130  GPAGLPGPRGPPGPPGIPGPAG-------ISVPGKPGQQGPTGAPGPRGFPGEKGA---- 178
            G  G  GP GPPGP G PG  G       I  PG+PG QGP GA G +G PGEKG     
Sbjct: 914  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 973

Query: 179  -----------------PGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTGPSGPP 217
                             PGV G +G KGE+G     G  G  GE G PGP GP GP G P
Sbjct: 974  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1033

Query: 218  GV----------------------GKRGENGVPGQ------PGIKGDRGFPGEMGPIGPP 249
            G                       G RG NG PG       PG  G++G  G++GP+GPP
Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1093

Query: 250  GPQGPPGERGPEG-------------IGKPGAAGAPGQPGIPGTKGLPGA---------- 286
            GP GP G  GP G             +G PG  G PG+ G PG +G PG           
Sbjct: 1094 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1153

Query: 287  -----PGIAGPPGPPG-------------FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
                 PG  GPPGP G              G PG PG  GE GP G  G  G +GE G  
Sbjct: 1154 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1213

Query: 329  GLPGKPGLTG---PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 385
            G PG PG TG   PPG +G +GP G PGS G  G KG  G  G  G PG  G  G  G  
Sbjct: 1214 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1273

Query: 386  GKPG---YPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442
            GKPG     G PG  G +G PG  G  G PG  GPPGLPG  G AGAKG  GH G  G  
Sbjct: 1274 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333

Query: 443  GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA-TKGLNGPTGPPGPPG---PR 498
            G PG  G +G  G PG  G PG KG+ G PG  GP G     GL GP GP G  G   P 
Sbjct: 1334 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1393

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGF-IKAGQRPSLSGTPLVSANQGV 546
            G  GE G+ GPPG PGPPG+ + P    +    R S+ G+ L+  ++ +
Sbjct: 1394 GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAI 1442



 Score =  428 bits (1101), Expect = e-120
 Identities = 258/606 (42%), Positives = 297/606 (49%), Gaps = 114/606 (18%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-------------YGSPGLQGEPGLPGPPG 101
            VRG  G  GP G  GP+G PGP G  G PG             +G  G QG+PGLPG PG
Sbjct: 540  VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599

Query: 102  PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG---------- 151
                G PG PG  G PG +G  GP G  GP G PGPRG  G  GI G  G          
Sbjct: 600  SD--GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657

Query: 152  ---------------ISVPGKPGQQ---------GPTGAPGPRGFPGEK------GAPGV 181
                           + VPG  G+          GPTG PGP G  GEK      G PG 
Sbjct: 658  PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 717

Query: 182  PGMNGQKGEMGY----GAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGIK-- 234
            PG  G KG +G+    GA G  G RGL G  GP G  GP G  G+RG  G  G+ G K  
Sbjct: 718  PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 777

Query: 235  ----------GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284
                      G+RG PG  GP G PGP+GPPG  G +G+  PG  G  G+ G  G  G P
Sbjct: 778  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 835

Query: 285  GAPGIAGP---------------PGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
            G PG+ GP               PGPPG  G+ GLPG  G+ G  G PG PGA G+ GPA
Sbjct: 836  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 895

Query: 329  GL---PGK---PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSP 382
            GL   PG+   PG  G PG  G +GP G PG  G PG +G  G  GP G PG  G +G P
Sbjct: 896  GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 955

Query: 383  GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442
            G+ G+ G PG+ G  GP G  G+ GP G PG  GPPG+ G  G  G  G PG  G  G +
Sbjct: 956  GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 1015

Query: 443  GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI----ATKGLNGPTGP------P 492
            G  G PG  GPIGP G PG  G+ G+PG+ GP G  G      T+G NGP GP      P
Sbjct: 1016 GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1075

Query: 493  GPPGPRGHSGEPGLPGPPGPPGPPGQA--------VMPEGFIKAGQRPSLSGTPLVSANQ 544
            GP G +G +G+ G  GPPGPPGP G A          P G +     P   G P  S + 
Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135

Query: 545  GVTGMP 550
            G+ G P
Sbjct: 1136 GIQGEP 1141



 Score =  428 bits (1100), Expect = e-120
 Identities = 247/549 (44%), Positives = 291/549 (53%), Gaps = 88/549 (16%)

Query: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----------GSPGLQGE---PGLPGPPG 101
           ++GE G  GP GP GP+G  GP G  G+ G           G PG++G+    GLPG PG
Sbjct: 423 LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 482

Query: 102 PSA-VGKPGVPGLPGKPGERGPYGPKGDVGPAGLP---GPR---GPPGPPGIPGPAGI-- 152
                G  G  GLPG PGE G  G  G++GP GLP   GPR   GP GPPGIPGP G+  
Sbjct: 483 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 542

Query: 153 --------------SVPGKPGQQ---------GPTGAPGPRGFPGEKGAPGVPGMNGQKG 189
                           PG PGQQ         GP GA GP G  G +G PG+PGM G  G
Sbjct: 543 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602

Query: 190 EMGY----GAPGRPGERGLPGPQGPTGPSGPPGV----------GKRGENGVPGQPGIKG 235
             G+    G PG  G +G  GPQGP G  GP GV          G +GE G  G PG KG
Sbjct: 603 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 662

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295
           D G  G+ G +G PG +G  G  GP+  G+ G  G PG PG+ G KG  G PG+ G PG 
Sbjct: 663 DIGVKGDRGEVGVPGSRGEDGPEGPK--GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 720

Query: 296 PG----FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
            G     G PG PG  GE+G  GL G  G +GE+GP G  G+ G  G  G  G +G  G 
Sbjct: 721 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 780

Query: 352 PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK------PGLDGPKGNPGL 405
            G HG PG +G  GP GP G+PG KG  G PG DG PG+PG+       G  GP G PG+
Sbjct: 781 DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 840

Query: 406 PGPKGDPGVGGP---PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGF 462
            GP+G  G  GP    G PGP GP G +G+PG  G+ G +G PG PG  G  GP G+ GF
Sbjct: 841 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 900

Query: 463 PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGE------PGLPGPPGPP 513
           PG +G PG+ G PG      KG  GP+GPPGP   PG RG +G       PG PGP GPP
Sbjct: 901 PGERGLPGTAGGPG-----LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 955

Query: 514 GPPGQAVMP 522
           G  G+  +P
Sbjct: 956 GAAGEKGVP 964



 Score =  427 bits (1098), Expect = e-119
 Identities = 250/565 (44%), Positives = 284/565 (50%), Gaps = 106/565 (18%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
           RG QG  GPPG AG RG  G  G  G PG     G  G  G PGLPG  G    G  G  
Sbjct: 436 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR--GDTGAQ 493

Query: 112 GLPGKPGERGPYGPKGDVGPAGLPG---PRG---PPGPPGIPGPAGI------------- 152
           GLPG PGE G  G  G++GP GLPG   PRG   P GPPGIPGP G+             
Sbjct: 494 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 553

Query: 153 ---SVPGKPGQQG---------PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAP 196
                PG PGQQG         P GA GP G  G +G PG+PGM G  G  G+    G P
Sbjct: 554 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 613

Query: 197 GRPGERGLPGPQGPTGPSGPPGV----------GKRGENGVPGQPGIKGDRGFPGEMGPI 246
           G  G +G  GPQGP G  GP GV          G +GE G  G PG KGD G  G+ G +
Sbjct: 614 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 673

Query: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPG 302
           G PG +G  G  GP+G  + G  G PG PG+ G KG  G PG+ G PG  G     G PG
Sbjct: 674 GVPGSRGEDGPEGPKG--RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 731

Query: 303 LPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362
            PG  GE+G  GL G  G +GE+GP G  G+ G  G  G  G +G  G  G HG PG +G
Sbjct: 732 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791

Query: 363 ETGPAGPAGYPGAKGERGSPGSDGKPGYPGK---------------PGLDGP-------- 399
             GP GP G+PG KG  G PG DG PG+PG+               PG+ GP        
Sbjct: 792 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 851

Query: 400 ----KGNPGLPGPKGDPGVGG------------PPGLPGPVGPAGAKGMPGHNGEAGPRG 443
               +G+PG PGP G+ G+ G            PPG PG  GPAG +G PG  G  G  G
Sbjct: 852 PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 911

Query: 444 APGIPGTRGPIGPPGIPGFPGSK---------GDPGSPGPPGPAGIA-TKGLNGPTGPPG 493
            PG+ G  GP GPPG  G PG +         G PG PGP GP G A  KG+ G  GP G
Sbjct: 912 GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 971

Query: 494 PPGPRGHSGEPGLPGPPGPPGPPGQ 518
           P G  G  G  GLPGP GPPG  G+
Sbjct: 972 PTGRDGVQGPVGLPGPAGPPGVAGE 996



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/581 (45%), Positives = 288/581 (49%), Gaps = 60/581 (10%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGP------PGPAGPRGHPGPSGPPG 81
            P G +GP      +     T KS      G  G  GP      PGP GP G PGP GPPG
Sbjct: 750  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 809

Query: 82   KPGY----GSPGLQGEPGL---PGPPGPSAV-------------------GKPGVPGLPG 115
             PG     G PG +GE G     GPPGP  V                   G PG PG  G
Sbjct: 810  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRG 171
             PG  G  G KGD GP G PG  GP G  G PG  G+      PG  G +GP+G PGP G
Sbjct: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 929

Query: 172  FPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRG 223
             PGE+GA G  G  G  G  G  G PG  GE+G+PG +GP GP+G  GV       G  G
Sbjct: 930  SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 989

Query: 224  ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIP---- 278
              GV G+ G KG+ G PG+ G  G  G  GPPG  GP G +G+PGAAGA G+PG      
Sbjct: 990  PPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1049

Query: 279  --GTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG 335
              G KG  G  G  GPPGP G  G PG  G KGE G  G  G PG  G +GPAG  G  G
Sbjct: 1050 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109

Query: 336  LTGPP---GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
              GPP   GN+GP G KG PG  G PG +GE G  GP G  G KGE G PG  G PG  G
Sbjct: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169

Query: 393  KPGLDGPKGNP---GLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPG 449
              G DGPKGNP   G PG  G PG GGP G  G  G  G  G PG  G  GP G  G PG
Sbjct: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229

Query: 450  TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-GLNGPTGPPGPPGPRGHSGEPGLPG 508
              G  GP G PG  G +G  G+ G PG  G   K G  GP GP G PGP G  G PG  G
Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289

Query: 509  PPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
              G PG  GQA  P G +     P L G       +G  G+
Sbjct: 1290 QQGRPGATGQA-GPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1329



 Score =  424 bits (1091), Expect = e-118
 Identities = 267/614 (43%), Positives = 294/614 (47%), Gaps = 115/614 (18%)

Query: 50   SKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPG---PPGP 102
            S G    G  G  G PGP GP G PGP GPPG PG     G PG +GE G  G   PPGP
Sbjct: 778  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 837

Query: 103  SAV-------------------GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143
              V                   G PG PG  G PG  G  G KGD GP G PG  GP G 
Sbjct: 838  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 897

Query: 144  PGIPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGR 198
             G PG  G+      PG  G +GP+G PGP G PGE+GA G  G  G  G  G  G PG 
Sbjct: 898  RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 957

Query: 199  PGERGLPGPQGPTGPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP 251
             GE+G+PG +GP GP+G  GV       G  G  GV G+ G KG+ G PG+ G  G  G 
Sbjct: 958  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1017

Query: 252  QGPPGERGPEG-IGKPGAAGAPGQPGIPG------TKGLPGAPGIAGPPGPPGF-GKPGL 303
             GPPG  GP G +G+PGAAGA G+PG  G       KG  G  G  GPPGP G  G PG 
Sbjct: 1018 HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP 1077

Query: 304  PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG---NMGPQGPKGIPGSHGLPGP 360
             G KGE G  G  G PG  G +GPAG  G  G  GPPG   N+GP G KG PG  G PG 
Sbjct: 1078 SGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI 1137

Query: 361  KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG---LPGPKGDPGVGGP 417
            +GE G  GP G  G KGE G PG  G PG  G  G DGPKGNPG    PG  G PG GGP
Sbjct: 1138 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP 1197

Query: 418  ---------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPG---------------- 446
                           PG PG  GP G  G PG  G+ GP G+PG                
Sbjct: 1198 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257

Query: 447  --IPGTRGPIGPPG---------IPGFPGSKGDPGSPG------PPGPAG---------- 479
               PG  GP+GP G         + G PGS G  G PG      PPGP G          
Sbjct: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1317

Query: 480  ---IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP--EGFIKAGQRPSL 534
                  KG  G  G  GPPG +G  G+ GLPGP G PG  G+  +P   G I  G  P L
Sbjct: 1318 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1377

Query: 535  SGTPLVSANQGVTG 548
             G       +G TG
Sbjct: 1378 PGPAGPKGAKGATG 1391



 Score =  422 bits (1085), Expect = e-118
 Identities = 260/581 (44%), Positives = 288/581 (49%), Gaps = 91/581 (15%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP----GLQGEPGLPGPPGPSAVGKP 108
            I  RG  G  GP G  GP+G PG  GPPG  G   P    G  G  G PGPPG    G P
Sbjct: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ--GTP 568

Query: 109  GVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168
            G  GLPG  G  GP+G KG  G  GLPG  G  GPPG PG  G   PG  G QGP+G  G
Sbjct: 569  GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG--PPGTKGNQGPSGPQG 626

Query: 169  PRGFPGEKGAPGVPGMNGQKGEMG----------------------YGAPGRPGERGLPG 206
            P G+PG +G  GV G+ G KG  G                       G PG  GE G  G
Sbjct: 627  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 686

Query: 207  PQGPTGPSGPPG----VGKRGENGVPGQPGI---------------------KGDRGFPG 241
            P+G TGP+G PG    +G++G+ GVPG PG                      KG RG  G
Sbjct: 687  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 746

Query: 242  EMGPIGPPGPQGPPGERGPEG-IGKPGAAGA---------PGQPGIPGTKGLPGAPGIAG 291
            + GP G  GP GP G+RGP G  GK GA G          PG+ G+PG +G  G PG  G
Sbjct: 747  KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG 806

Query: 292  PPGPPG-FGKPGLPGLKGE---------RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
            PPGPPG  G PG PG +GE          GP G+ G  GA GE GP G  G PG  GPPG
Sbjct: 807  PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 866

Query: 342  NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
              G  G  G  G+ G PGP G  G  GPAG  G  GERG PG+ G PG  G  G  GP G
Sbjct: 867  EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 926

Query: 402  NPGLPGPKGDPGVG---GPPGLPGPVGP---AGAKGMPGHNGEAGPRGAPGIP---GTRG 452
              G PG +G  G G   GPPG PGP GP   AG KG+PG  G  GP G  G+    G  G
Sbjct: 927  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 986

Query: 453  PIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGP 512
            P GPPG+ G  G KG+ G PG  G  G   KG +GP GPPGP GP G  G  G  G PG 
Sbjct: 987  PAGPPGVAGEDGDKGEVGDPGQKGTKG--NKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1044

Query: 513  PGPPGQ--AVMPEGFIKAGQRP---SLSGTPLVSANQGVTG 548
             GP G   A   EG       P    L G P  S  +G TG
Sbjct: 1045 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085



 Score =  394 bits (1011), Expect = e-109
 Identities = 245/600 (40%), Positives = 282/600 (47%), Gaps = 107/600 (17%)

Query: 52  GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP----GLQGEPGLPGPPGPSAV-- 105
           G+ V G  G  GP G  GP G  G  GP G PG   P    GL G  G PGPPG S +  
Sbjct: 308 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 367

Query: 106 ---------------------------------GKPGVPGLPGKPGERGPYGPKGDVGPA 132
                                            G PG  G  G+PG  G  G  G  G +
Sbjct: 368 FRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 427

Query: 133 GLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA---------PGVPG 183
           G  GP+GP GP G+ GP     PGK G++G  GA G RG PG+ G          PG+PG
Sbjct: 428 GDLGPQGPRGPQGLTGP-----PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 482

Query: 184 MNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKG 235
             G +G+ G  G PG PGE G  G  G  GP G PG       +G +G  G+PG PG++G
Sbjct: 483 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 542

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294
             G  G  G +GP G  GPPG++G  G  G PG  GA G  G  G +G PG PG+ G  G
Sbjct: 543 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602

Query: 295 PPGF-GKPGLPGLKGERGPAGLPGGP----------------GAKGEQGPAGLPGKPGLT 337
           PPG  GK G PG KG +GP+G P GP                G KG +G  G  G PG  
Sbjct: 603 PPGHPGKEGPPGTKGNQGPSG-PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 661

Query: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
           G  G  G +G  G+PGS G  GP+G  G  GP G PG  G  G  G  G PG PG PG  
Sbjct: 662 GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 721

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTR------ 451
           GPKG+ G PG  G  G  G  GL G  GP G +G  G  G+ GPRGA G  G +      
Sbjct: 722 GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 781

Query: 452 GPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-------------GLNGPTGPPGPPGPR 498
           GP GPPG  G PG +G  G PGP GP G   K             G  G TGPPGPPG  
Sbjct: 782 GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 841

Query: 499 GHSGEPGLPGP------PGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMP 550
           G  G  G  GP      PGPPGPPG+  +P    K G +  P   G P      G+ G P
Sbjct: 842 GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 901



 Score =  383 bits (984), Expect = e-106
 Identities = 237/529 (44%), Positives = 268/529 (50%), Gaps = 79/529 (14%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------------GSPGLQGEPGLPGPPGPS 103
            GE+G  G  GP GP G PGP GPPG  G              G  G+QG  GLPGP GP 
Sbjct: 932  GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 991

Query: 104  AV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQG 162
             V G+ G  G  G PG++G  G KG+ GP G PGP GP G PG  G  G   PG  G QG
Sbjct: 992  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG--EPGARGPQG 1049

Query: 163  PTGAPGP---RGF---PGEKGAPGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTG 212
              GA G    RGF   PG  G  G+PG +G+KGE G     G PG PG RG  GP G  G
Sbjct: 1050 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109

Query: 213  PSGPPG-------------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259
            P GPPG              G+ G  G+ G+PG+KG RG  GE G  G PG  GPPG +G
Sbjct: 1110 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169

Query: 260  PEGI----GKPGAAGAPGQPGIPG---------TKGLPGAPGIAGPPGPPG-FGKPGLPG 305
            P G     G PG  G PG PG PG          KG  G  G  G PG PG  G+ G PG
Sbjct: 1170 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1229

Query: 306  LKGERGPAGLPG------GPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---KGIPGS-- 354
              G+RGPAG PG      G GAKG+ G  G PGK G  GP G  G  GP   +G+PGS  
Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289

Query: 355  -HGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP------KGNPGLPG 407
              G PG  G+ GP GP G PG  G RG  G+ G+ G+PG  GL GP      KG+ GLPG
Sbjct: 1290 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1349

Query: 408  PKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKG 467
            P+G PG  G  G+PG  GP G  G PG  G AGP+GA G  G  GP G  G+ G PG  G
Sbjct: 1350 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPG 1409

Query: 468  DPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP--GPPGPPG 514
             PG    P P  +  K            G R    +  +P  G PG PG
Sbjct: 1410 PPGEVIQPLPIQMPKKTRR------SVDGSRLMQEDEAIPTGGAPGSPG 1452



 Score =  368 bits (944), Expect = e-101
 Identities = 230/575 (40%), Positives = 270/575 (46%), Gaps = 99/575 (17%)

Query: 64  PPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPY 123
           PP      G  G  G  G+P    PG+  E    GPPGP      G  GL G PG +G  
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVE----GPPGPE-----GPAGLIGPPGIQGNP 333

Query: 124 GPKGDVGPAGLPGPRGPPGPPGIPGPAGISV------PGKPGQQGPT------------- 164
           GP GD G  G PG  G PG  G PGP G S+          G +GP              
Sbjct: 334 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 393

Query: 165 -------GAPGPRGF---PGEKGAPGVPGMNGQKGEMG----------YGAPGRPGERGL 204
                  G PGP G+   PG  G PG PG+ G+ G++G           G PG+ G RG 
Sbjct: 394 QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 453

Query: 205 PGPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPP------------GP 251
            G  G  G  G PGV G RG +G+PG PG KG RG  G  G  GPP            GP
Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 513

Query: 252 QGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGE 309
           +G PGE GP G +G  G  G PG PG+ G  G  G  G  GP G PG  G+ G PG +G 
Sbjct: 514 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 573

Query: 310 RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGP 369
            GP G  G  G KG QG  GLPG PG  GPPG+ G +GP G  G+ G  GP+G  G  GP
Sbjct: 574 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 633

Query: 370 AGYPGA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGP 423
            G  G       KG +G  G DG PG+ G  G+ G +G  G+PG +G+ G  GP G  GP
Sbjct: 634 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 693

Query: 424 VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------------ 471
            G  G  G+ G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+            
Sbjct: 694 TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE 753

Query: 472 PGPPGPAG----------IATKGLNGPTGPPGPPGPR---GHSGEPGLPGPPGPPGPPGQ 518
            GP GP G             KG +G  GP GPPG R   G  G  G PGP GPPGPPG+
Sbjct: 754 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 813

Query: 519 AVMP-----EGFIKAGQRPSLSGTPLVSANQGVTG 548
             +P      G +    +    G P V   QG  G
Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 848



 Score =  267 bits (682), Expect = 3e-71
 Identities = 169/405 (41%), Positives = 192/405 (47%), Gaps = 88/405 (21%)

Query: 224 ENGVPGQPGIKGDRGFPGEMGP----IGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIP 278
           E    G  G+KG++G P  + P     GPPGP+GP G  GP GI G PG  G PG+ G P
Sbjct: 286 EEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPP 345

Query: 279 GTKGLPGAPGIAGPPG-----PPGFGK------------------------------PGL 303
           G  GLPG+ G  GPPG     P  FG                               PG 
Sbjct: 346 GRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP 405

Query: 304 PGLKGERGPAGLPGGPGAKGEQG---PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360
            G  G  GP G PG PG KGE G   P G  G  GLTGPPG  G +G  G  G+ G+PG 
Sbjct: 406 MGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 465

Query: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD---------GPKGNP------GL 405
            G  G  G  G PG  GE+G  G  G  G PG PG D         GP+G P      GL
Sbjct: 466 PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGL 525

Query: 406 PGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT--------------- 450
            GPKG PG+ GPPG+ G  GP G KG  G  GE GP G  G PGT               
Sbjct: 526 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGE 585

Query: 451 RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGEPGLP 507
           +GP G PG+PG PGS G PG PG  GP G  TKG  GP+GP GP   PGPRG  G  G+ 
Sbjct: 586 KGPQGKPGLPGMPGSDGPPGHPGKEGPPG--TKGNQGPSGPQGPLGYPGPRGVKGVDGIR 643

Query: 508 GPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVS 552
           G  G  G  G+    +GF      P   G   V  ++G  G+P S
Sbjct: 644 GLKGHKGEKGE----DGF------PGFKGDIGVKGDRGEVGVPGS 678


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  429 bits (1103), Expect = e-120
 Identities = 272/649 (41%), Positives = 309/649 (47%), Gaps = 130/649 (20%)

Query: 26   QMPTGIKGPL--PNTKTQFFIPYTIKSKG-IAVRGEQGTPGPPGPAGP------------ 70
            Q P G  GP   P    +  +P     +G +  +G+ G PGPPG  GP            
Sbjct: 775  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 834

Query: 71   RGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV 129
            RGHPGP GPPG+ G  G+ G +G  G PGPPG  A GK G  GL G PGERG  G  G  
Sbjct: 835  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG--APGKDGPAGLRGFPGERGLPGTAGGP 892

Query: 130  GPAGLPGPRGPPGPPGIPGPAG-------ISVPGKPGQQGPTGAPGPRGFPGEKGA---- 178
            G  G  GP GPPGP G PG  G       I  PG+PG QGP GA G +G PGEKG     
Sbjct: 893  GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 952

Query: 179  -----------------PGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTGPSGPP 217
                             PGV G +G KGE+G     G  G  GE G PGP GP GP G P
Sbjct: 953  GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1012

Query: 218  GV----------------------GKRGENGVPGQ------PGIKGDRGFPGEMGPIGPP 249
            G                       G RG NG PG       PG  G++G  G++GP+GPP
Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1072

Query: 250  GPQGPPGERGPEG-------------IGKPGAAGAPGQPGIPGTKGLPGA---------- 286
            GP GP G  GP G             +G PG  G PG+ G PG +G PG           
Sbjct: 1073 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1132

Query: 287  -----PGIAGPPGPPG-------------FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
                 PG  GPPGP G              G PG PG  GE GP G  G  G +GE G  
Sbjct: 1133 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1192

Query: 329  GLPGKPGLTG---PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 385
            G PG PG TG   PPG +G +GP G PGS G  G KG  G  G  G PG  G  G  G  
Sbjct: 1193 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252

Query: 386  GKPG---YPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442
            GKPG     G PG  G +G PG  G  G PG  GPPGLPG  G AGAKG  GH G  G  
Sbjct: 1253 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312

Query: 443  GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA-TKGLNGPTGPPGPPG---PR 498
            G PG  G +G  G PG  G PG KG+ G PG  GP G     GL GP GP G  G   P 
Sbjct: 1313 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1372

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGF-IKAGQRPSLSGTPLVSANQGV 546
            G  GE G+ GPPG PGPPG+ + P    +    R S+ G+ L+  ++ +
Sbjct: 1373 GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAI 1421



 Score =  428 bits (1101), Expect = e-120
 Identities = 258/606 (42%), Positives = 297/606 (49%), Gaps = 114/606 (18%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-------------YGSPGLQGEPGLPGPPG 101
            VRG  G  GP G  GP+G PGP G  G PG             +G  G QG+PGLPG PG
Sbjct: 519  VRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578

Query: 102  PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG---------- 151
                G PG PG  G PG +G  GP G  GP G PGPRG  G  GI G  G          
Sbjct: 579  SD--GPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636

Query: 152  ---------------ISVPGKPGQQ---------GPTGAPGPRGFPGEK------GAPGV 181
                           + VPG  G+          GPTG PGP G  GEK      G PG 
Sbjct: 637  PGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGY 696

Query: 182  PGMNGQKGEMGY----GAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGIK-- 234
            PG  G KG +G+    GA G  G RGL G  GP G  GP G  G+RG  G  G+ G K  
Sbjct: 697  PGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGT 756

Query: 235  ----------GDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284
                      G+RG PG  GP G PGP+GPPG  G +G+  PG  G  G+ G  G  G P
Sbjct: 757  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEVGFQGKTGPP 814

Query: 285  GAPGIAGP---------------PGPPG-FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
            G PG+ GP               PGPPG  G+ GLPG  G+ G  G PG PGA G+ GPA
Sbjct: 815  GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPA 874

Query: 329  GL---PGK---PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSP 382
            GL   PG+   PG  G PG  G +GP G PG  G PG +G  G  GP G PG  G +G P
Sbjct: 875  GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 934

Query: 383  GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442
            G+ G+ G PG+ G  GP G  G+ GP G PG  GPPG+ G  G  G  G PG  G  G +
Sbjct: 935  GAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNK 994

Query: 443  GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI----ATKGLNGPTGP------P 492
            G  G PG  GPIGP G PG  G+ G+PG+ GP G  G      T+G NGP GP      P
Sbjct: 995  GEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLP 1054

Query: 493  GPPGPRGHSGEPGLPGPPGPPGPPGQA--------VMPEGFIKAGQRPSLSGTPLVSANQ 544
            GP G +G +G+ G  GPPGPPGP G A          P G +     P   G P  S + 
Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114

Query: 545  GVTGMP 550
            G+ G P
Sbjct: 1115 GIQGEP 1120



 Score =  428 bits (1100), Expect = e-120
 Identities = 247/549 (44%), Positives = 291/549 (53%), Gaps = 88/549 (16%)

Query: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----------GSPGLQGE---PGLPGPPG 101
           ++GE G  GP GP GP+G  GP G  G+ G           G PG++G+    GLPG PG
Sbjct: 402 LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 461

Query: 102 PSA-VGKPGVPGLPGKPGERGPYGPKGDVGPAGLP---GPR---GPPGPPGIPGPAGI-- 152
                G  G  GLPG PGE G  G  G++GP GLP   GPR   GP GPPGIPGP G+  
Sbjct: 462 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521

Query: 153 --------------SVPGKPGQQ---------GPTGAPGPRGFPGEKGAPGVPGMNGQKG 189
                           PG PGQQ         GP GA GP G  G +G PG+PGM G  G
Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 190 EMGY----GAPGRPGERGLPGPQGPTGPSGPPGV----------GKRGENGVPGQPGIKG 235
             G+    G PG  G +G  GPQGP G  GP GV          G +GE G  G PG KG
Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295
           D G  G+ G +G PG +G  G  GP+  G+ G  G PG PG+ G KG  G PG+ G PG 
Sbjct: 642 DIGVKGDRGEVGVPGSRGEDGPEGPK--GRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGR 699

Query: 296 PG----FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
            G     G PG PG  GE+G  GL G  G +GE+GP G  G+ G  G  G  G +G  G 
Sbjct: 700 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 759

Query: 352 PGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK------PGLDGPKGNPGL 405
            G HG PG +G  GP GP G+PG KG  G PG DG PG+PG+       G  GP G PG+
Sbjct: 760 DGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGV 819

Query: 406 PGPKGDPGVGGP---PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGF 462
            GP+G  G  GP    G PGP GP G +G+PG  G+ G +G PG PG  G  GP G+ GF
Sbjct: 820 VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGF 879

Query: 463 PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGP---PGPRGHSGE------PGLPGPPGPP 513
           PG +G PG+ G PG      KG  GP+GPPGP   PG RG +G       PG PGP GPP
Sbjct: 880 PGERGLPGTAGGPG-----LKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP 934

Query: 514 GPPGQAVMP 522
           G  G+  +P
Sbjct: 935 GAAGEKGVP 943



 Score =  427 bits (1098), Expect = e-119
 Identities = 250/565 (44%), Positives = 284/565 (50%), Gaps = 106/565 (18%)

Query: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
           RG QG  GPPG AG RG  G  G  G PG     G  G  G PGLPG  G    G  G  
Sbjct: 415 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR--GDTGAQ 472

Query: 112 GLPGKPGERGPYGPKGDVGPAGLPG---PRG---PPGPPGIPGPAGI------------- 152
           GLPG PGE G  G  G++GP GLPG   PRG   P GPPGIPGP G+             
Sbjct: 473 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532

Query: 153 ---SVPGKPGQQG---------PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAP 196
                PG PGQQG         P GA GP G  G +G PG+PGM G  G  G+    G P
Sbjct: 533 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 592

Query: 197 GRPGERGLPGPQGPTGPSGPPGV----------GKRGENGVPGQPGIKGDRGFPGEMGPI 246
           G  G +G  GPQGP G  GP GV          G +GE G  G PG KGD G  G+ G +
Sbjct: 593 GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 652

Query: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPG 302
           G PG +G  G  GP+G  + G  G PG PG+ G KG  G PG+ G PG  G     G PG
Sbjct: 653 GVPGSRGEDGPEGPKG--RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 710

Query: 303 LPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362
            PG  GE+G  GL G  G +GE+GP G  G+ G  G  G  G +G  G  G HG PG +G
Sbjct: 711 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 770

Query: 363 ETGPAGPAGYPGAKGERGSPGSDGKPGYPGK---------------PGLDGP-------- 399
             GP GP G+PG KG  G PG DG PG+PG+               PG+ GP        
Sbjct: 771 LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 830

Query: 400 ----KGNPGLPGPKGDPGVGG------------PPGLPGPVGPAGAKGMPGHNGEAGPRG 443
               +G+PG PGP G+ G+ G            PPG PG  GPAG +G PG  G  G  G
Sbjct: 831 PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 890

Query: 444 APGIPGTRGPIGPPGIPGFPGSK---------GDPGSPGPPGPAGIA-TKGLNGPTGPPG 493
            PG+ G  GP GPPG  G PG +         G PG PGP GP G A  KG+ G  GP G
Sbjct: 891 GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 950

Query: 494 PPGPRGHSGEPGLPGPPGPPGPPGQ 518
           P G  G  G  GLPGP GPPG  G+
Sbjct: 951 PTGRDGVQGPVGLPGPAGPPGVAGE 975



 Score =  427 bits (1097), Expect = e-119
 Identities = 263/581 (45%), Positives = 288/581 (49%), Gaps = 60/581 (10%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGP------PGPAGPRGHPGPSGPPG 81
            P G +GP      +     T KS      G  G  GP      PGP GP G PGP GPPG
Sbjct: 729  PRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPG 788

Query: 82   KPGY----GSPGLQGEPGL---PGPPGPSAV-------------------GKPGVPGLPG 115
             PG     G PG +GE G     GPPGP  V                   G PG PG  G
Sbjct: 789  PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848

Query: 116  KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI----SVPGKPGQQGPTGAPGPRG 171
             PG  G  G KGD GP G PG  GP G  G PG  G+      PG  G +GP+G PGP G
Sbjct: 849  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908

Query: 172  FPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRG 223
             PGE+GA G  G  G  G  G  G PG  GE+G+PG +GP GP+G  GV       G  G
Sbjct: 909  SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 968

Query: 224  ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIP---- 278
              GV G+ G KG+ G PG+ G  G  G  GPPG  GP G +G+PGAAGA G+PG      
Sbjct: 969  PPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1028

Query: 279  --GTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPG 335
              G KG  G  G  GPPGP G  G PG  G KGE G  G  G PG  G +GPAG  G  G
Sbjct: 1029 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088

Query: 336  LTGPP---GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
              GPP   GN+GP G KG PG  G PG +GE G  GP G  G KGE G PG  G PG  G
Sbjct: 1089 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148

Query: 393  KPGLDGPKGNP---GLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPG 449
              G DGPKGNP   G PG  G PG GGP G  G  G  G  G PG  G  GP G  G PG
Sbjct: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208

Query: 450  TRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-GLNGPTGPPGPPGPRGHSGEPGLPG 508
              G  GP G PG  G +G  G+ G PG  G   K G  GP GP G PGP G  G PG  G
Sbjct: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268

Query: 509  PPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
              G PG  GQA  P G +     P L G       +G  G+
Sbjct: 1269 QQGRPGATGQA-GPPGPVGPPGLPGLRGDAGAKGEKGHPGL 1308



 Score =  424 bits (1091), Expect = e-118
 Identities = 267/614 (43%), Positives = 294/614 (47%), Gaps = 115/614 (18%)

Query: 50   SKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPG---PPGP 102
            S G    G  G  G PGP GP G PGP GPPG PG     G PG +GE G  G   PPGP
Sbjct: 757  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 816

Query: 103  SAV-------------------GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143
              V                   G PG PG  G PG  G  G KGD GP G PG  GP G 
Sbjct: 817  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 876

Query: 144  PGIPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGR 198
             G PG  G+      PG  G +GP+G PGP G PGE+GA G  G  G  G  G  G PG 
Sbjct: 877  RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 936

Query: 199  PGERGLPGPQGPTGPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP 251
             GE+G+PG +GP GP+G  GV       G  G  GV G+ G KG+ G PG+ G  G  G 
Sbjct: 937  AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996

Query: 252  QGPPGERGPEG-IGKPGAAGAPGQPGIPG------TKGLPGAPGIAGPPGPPGF-GKPGL 303
             GPPG  GP G +G+PGAAGA G+PG  G       KG  G  G  GPPGP G  G PG 
Sbjct: 997  HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP 1056

Query: 304  PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG---NMGPQGPKGIPGSHGLPGP 360
             G KGE G  G  G PG  G +GPAG  G  G  GPPG   N+GP G KG PG  G PG 
Sbjct: 1057 SGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI 1116

Query: 361  KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG---LPGPKGDPGVGGP 417
            +GE G  GP G  G KGE G PG  G PG  G  G DGPKGNPG    PG  G PG GGP
Sbjct: 1117 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP 1176

Query: 418  ---------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPG---------------- 446
                           PG PG  GP G  G PG  G+ GP G+PG                
Sbjct: 1177 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236

Query: 447  --IPGTRGPIGPPG---------IPGFPGSKGDPGSPG------PPGPAG---------- 479
               PG  GP+GP G         + G PGS G  G PG      PPGP G          
Sbjct: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296

Query: 480  ---IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP--EGFIKAGQRPSL 534
                  KG  G  G  GPPG +G  G+ GLPGP G PG  G+  +P   G I  G  P L
Sbjct: 1297 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1356

Query: 535  SGTPLVSANQGVTG 548
             G       +G TG
Sbjct: 1357 PGPAGPKGAKGATG 1370



 Score =  422 bits (1085), Expect = e-118
 Identities = 260/581 (44%), Positives = 288/581 (49%), Gaps = 91/581 (15%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP----GLQGEPGLPGPPGPSAVGKP 108
            I  RG  G  GP G  GP+G PG  GPPG  G   P    G  G  G PGPPG    G P
Sbjct: 490  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQ--GTP 547

Query: 109  GVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPG 168
            G  GLPG  G  GP+G KG  G  GLPG  G  GPPG PG  G   PG  G QGP+G  G
Sbjct: 548  GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG--PPGTKGNQGPSGPQG 605

Query: 169  PRGFPGEKGAPGVPGMNGQKGEMG----------------------YGAPGRPGERGLPG 206
            P G+PG +G  GV G+ G KG  G                       G PG  GE G  G
Sbjct: 606  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665

Query: 207  PQGPTGPSGPPG----VGKRGENGVPGQPGI---------------------KGDRGFPG 241
            P+G TGP+G PG    +G++G+ GVPG PG                      KG RG  G
Sbjct: 666  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG 725

Query: 242  EMGPIGPPGPQGPPGERGPEG-IGKPGAAGA---------PGQPGIPGTKGLPGAPGIAG 291
            + GP G  GP GP G+RGP G  GK GA G          PG+ G+PG +G  G PG  G
Sbjct: 726  KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKG 785

Query: 292  PPGPPG-FGKPGLPGLKGE---------RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
            PPGPPG  G PG PG +GE          GP G+ G  GA GE GP G  G PG  GPPG
Sbjct: 786  PPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPG 845

Query: 342  NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
              G  G  G  G+ G PGP G  G  GPAG  G  GERG PG+ G PG  G  G  GP G
Sbjct: 846  EQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPG 905

Query: 402  NPGLPGPKGDPGVG---GPPGLPGPVGP---AGAKGMPGHNGEAGPRGAPGIP---GTRG 452
              G PG +G  G G   GPPG PGP GP   AG KG+PG  G  GP G  G+    G  G
Sbjct: 906  PAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPG 965

Query: 453  PIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGP 512
            P GPPG+ G  G KG+ G PG  G  G   KG +GP GPPGP GP G  G  G  G PG 
Sbjct: 966  PAGPPGVAGEDGDKGEVGDPGQKGTKG--NKGEHGPPGPPGPIGPVGQPGAAGADGEPGA 1023

Query: 513  PGPPGQ--AVMPEGFIKAGQRP---SLSGTPLVSANQGVTG 548
             GP G   A   EG       P    L G P  S  +G TG
Sbjct: 1024 RGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064



 Score =  394 bits (1011), Expect = e-109
 Identities = 245/600 (40%), Positives = 282/600 (47%), Gaps = 107/600 (17%)

Query: 52  GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP----GLQGEPGLPGPPGPSAV-- 105
           G+ V G  G  GP G  GP G  G  GP G PG   P    GL G  G PGPPG S +  
Sbjct: 287 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLP 346

Query: 106 ---------------------------------GKPGVPGLPGKPGERGPYGPKGDVGPA 132
                                            G PG  G  G+PG  G  G  G  G +
Sbjct: 347 FRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGES 406

Query: 133 GLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA---------PGVPG 183
           G  GP+GP GP G+ GP     PGK G++G  GA G RG PG+ G          PG+PG
Sbjct: 407 GDLGPQGPRGPQGLTGP-----PGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 461

Query: 184 MNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPG-------VGKRGENGVPGQPGIKG 235
             G +G+ G  G PG PGE G  G  G  GP G PG       +G +G  G+PG PG++G
Sbjct: 462 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG 294
             G  G  G +GP G  GPPG++G  G  G PG  GA G  G  G +G PG PG+ G  G
Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 295 PPGF-GKPGLPGLKGERGPAGLPGGP----------------GAKGEQGPAGLPGKPGLT 337
           PPG  GK G PG KG +GP+G P GP                G KG +G  G  G PG  
Sbjct: 582 PPGHPGKEGPPGTKGNQGPSG-PQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFK 640

Query: 338 GPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLD 397
           G  G  G +G  G+PGS G  GP+G  G  GP G PG  G  G  G  G PG PG PG  
Sbjct: 641 GDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 700

Query: 398 GPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTR------ 451
           GPKG+ G PG  G  G  G  GL G  GP G +G  G  G+ GPRGA G  G +      
Sbjct: 701 GPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 760

Query: 452 GPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-------------GLNGPTGPPGPPGPR 498
           GP GPPG  G PG +G  G PGP GP G   K             G  G TGPPGPPG  
Sbjct: 761 GPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVV 820

Query: 499 GHSGEPGLPGP------PGPPGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMP 550
           G  G  G  GP      PGPPGPPG+  +P    K G +  P   G P      G+ G P
Sbjct: 821 GPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFP 880



 Score =  383 bits (984), Expect = e-106
 Identities = 237/529 (44%), Positives = 268/529 (50%), Gaps = 79/529 (14%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------------GSPGLQGEPGLPGPPGPS 103
            GE+G  G  GP GP G PGP GPPG  G              G  G+QG  GLPGP GP 
Sbjct: 911  GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 970

Query: 104  AV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQG 162
             V G+ G  G  G PG++G  G KG+ GP G PGP GP G PG  G  G   PG  G QG
Sbjct: 971  GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG--EPGARGPQG 1028

Query: 163  PTGAPGP---RGF---PGEKGAPGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTG 212
              GA G    RGF   PG  G  G+PG +G+KGE G     G PG PG RG  GP G  G
Sbjct: 1029 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088

Query: 213  PSGPPG-------------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259
            P GPPG              G+ G  G+ G+PG+KG RG  GE G  G PG  GPPG +G
Sbjct: 1089 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148

Query: 260  PEGI----GKPGAAGAPGQPGIPG---------TKGLPGAPGIAGPPGPPG-FGKPGLPG 305
            P G     G PG  G PG PG PG          KG  G  G  G PG PG  G+ G PG
Sbjct: 1149 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1208

Query: 306  LKGERGPAGLPG------GPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---KGIPGS-- 354
              G+RGPAG PG      G GAKG+ G  G PGK G  GP G  G  GP   +G+PGS  
Sbjct: 1209 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1268

Query: 355  -HGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP------KGNPGLPG 407
              G PG  G+ GP GP G PG  G RG  G+ G+ G+PG  GL GP      KG+ GLPG
Sbjct: 1269 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1328

Query: 408  PKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKG 467
            P+G PG  G  G+PG  GP G  G PG  G AGP+GA G  G  GP G  G+ G PG  G
Sbjct: 1329 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPG 1388

Query: 468  DPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP--GPPGPPG 514
             PG    P P  +  K            G R    +  +P  G PG PG
Sbjct: 1389 PPGEVIQPLPIQMPKKTRR------SVDGSRLMQEDEAIPTGGAPGSPG 1431



 Score =  367 bits (941), Expect = e-101
 Identities = 229/575 (39%), Positives = 270/575 (46%), Gaps = 105/575 (18%)

Query: 74  PGPSGPPGKPGYGSPGLQGEPGLP----------GPPGPSAVGKPGVPGLPGKPGERGPY 123
           P    P  +  +G  GL+GE G P          GPPGP      G  GL G PG +G  
Sbjct: 258 PQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE-----GPAGLIGPPGIQGNP 312

Query: 124 GPKGDVGPAGLPGPRGPPGPPGIPGPAGISV------PGKPGQQGPT------------- 164
           GP GD G  G PG  G PG  G PGP G S+          G +GP              
Sbjct: 313 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 372

Query: 165 -------GAPGPRGF---PGEKGAPGVPGMNGQKGEMG----------YGAPGRPGERGL 204
                  G PGP G+   PG  G PG PG+ G+ G++G           G PG+ G RG 
Sbjct: 373 QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 432

Query: 205 PGPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPP------------GP 251
            G  G  G  G PGV G RG +G+PG PG KG RG  G  G  GPP            GP
Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGP 492

Query: 252 QGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGE 309
           +G PGE GP G +G  G  G PG PG+ G  G  G  G  GP G PG  G+ G PG +G 
Sbjct: 493 RGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGL 552

Query: 310 RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGP 369
            GP G  G  G KG QG  GLPG PG  GPPG+ G +GP G  G+ G  GP+G  G  GP
Sbjct: 553 PGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 612

Query: 370 AGYPGA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGP 423
            G  G       KG +G  G DG PG+ G  G+ G +G  G+PG +G+ G  GP G  GP
Sbjct: 613 RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 672

Query: 424 VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------------ 471
            G  G  G+ G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+            
Sbjct: 673 TGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE 732

Query: 472 PGPPGPAG----------IATKGLNGPTGPPGPPGPR---GHSGEPGLPGPPGPPGPPGQ 518
            GP GP G             KG +G  GP GPPG R   G  G  G PGP GPPGPPG+
Sbjct: 733 RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGK 792

Query: 519 AVMP-----EGFIKAGQRPSLSGTPLVSANQGVTG 548
             +P      G +    +    G P V   QG  G
Sbjct: 793 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 827



 Score =  268 bits (685), Expect = 1e-71
 Identities = 178/439 (40%), Positives = 203/439 (46%), Gaps = 98/439 (22%)

Query: 200 GERGLPGPQGP----TGPSGPPGVGKRGENGVP------GQPGIKGDRGFPGEMGP---- 245
           G+R  P  Q P      P   P    R +N  P      G  G+KG++G P  + P    
Sbjct: 231 GQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLV 290

Query: 246 IGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG-----PPGFG 299
            GPPGP+GP G  GP GI G PG  G PG+ G PG  GLPG+ G  GPPG     P  FG
Sbjct: 291 EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 350

Query: 300 K------------------------------PGLPGLKGERGPAGLPGGPGAKGEQG--- 326
                                          PG  G  G  GP G PG PG KGE G   
Sbjct: 351 SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG 410

Query: 327 PAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDG 386
           P G  G  GLTGPPG  G +G  G  G+ G+PG  G  G  G  G PG  GE+G  G  G
Sbjct: 411 PQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTG 470

Query: 387 KPGYPGKPGLD---------GPKGNP------GLPGPKGDPGVGGPPGLPGPVGPAGAKG 431
             G PG PG D         GP+G P      GL GPKG PG+ GPPG+ G  GP G KG
Sbjct: 471 AQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKG 530

Query: 432 MPGHNGEAGPRGAPGIPGT---------------RGPIGPPGIPGFPGSKGDPGSPGPPG 476
             G  GE GP G  G PGT               +GP G PG+PG PGS G PG PG  G
Sbjct: 531 SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 590

Query: 477 PAGIATKGLNGPTGPPGP---PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPS 533
           P G  TKG  GP+GP GP   PGPRG  G  G+ G  G  G  G+    +GF      P 
Sbjct: 591 PPG--TKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE----DGF------PG 638

Query: 534 LSGTPLVSANQGVTGMPVS 552
             G   V  ++G  G+P S
Sbjct: 639 FKGDIGVKGDRGEVGVPGS 657


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  429 bits (1103), Expect = e-120
 Identities = 272/649 (41%), Positives = 309/649 (47%), Gaps = 130/649 (20%)

Query: 26   QMPTGIKGPL--PNTKTQFFIPYTIKSKG-IAVRGEQGTPGPPGPAGP------------ 70
            Q P G  GP   P    +  +P     +G +  +G+ G PGPPG  GP            
Sbjct: 882  QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGE 941

Query: 71   RGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV 129
            RGHPGP GPPG+ G  G+ G +G  G PGPPG  A GK G  GL G PGERG  G  G  
Sbjct: 942  RGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG--APGKDGPAGLRGFPGERGLPGTAGGP 999

Query: 130  GPAGLPGPRGPPGPPGIPGPAG-------ISVPGKPGQQGPTGAPGPRGFPGEKGA---- 178
            G  G  GP GPPGP G PG  G       I  PG+PG QGP GA G +G PGEKG     
Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPT 1059

Query: 179  -----------------PGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTGPSGPP 217
                             PGV G +G KGE+G     G  G  GE G PGP GP GP G P
Sbjct: 1060 GRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP 1119

Query: 218  GV----------------------GKRGENGVPGQ------PGIKGDRGFPGEMGPIGPP 249
            G                       G RG NG PG       PG  G++G  G++GP+GPP
Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1179

Query: 250  GPQGPPGERGPEG-------------IGKPGAAGAPGQPGIPGTKGLPGA---------- 286
            GP GP G  GP G             +G PG  G PG+ G PG +G PG           
Sbjct: 1180 GPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEK 1239

Query: 287  -----PGIAGPPGPPG-------------FGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328
                 PG  GPPGP G              G PG PG  GE GP G  G  G +GE G  
Sbjct: 1240 GESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEP 1299

Query: 329  GLPGKPGLTG---PPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD 385
            G PG PG TG   PPG +G +GP G PGS G  G KG  G  G  G PG  G  G  G  
Sbjct: 1300 GQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359

Query: 386  GKPG---YPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPR 442
            GKPG     G PG  G +G PG  G  G PG  GPPGLPG  G AGAKG  GH G  G  
Sbjct: 1360 GKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419

Query: 443  GAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA-TKGLNGPTGPPGPPG---PR 498
            G PG  G +G  G PG  G PG KG+ G PG  GP G     GL GP GP G  G   P 
Sbjct: 1420 GPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPG 1479

Query: 499  GHSGEPGLPGPPGPPGPPGQAVMPEGF-IKAGQRPSLSGTPLVSANQGV 546
            G  GE G+ GPPG PGPPG+ + P    +    R S+ G+ L+  ++ +
Sbjct: 1480 GPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAI 1528



 Score =  429 bits (1102), Expect = e-120
 Identities = 261/615 (42%), Positives = 304/615 (49%), Gaps = 122/615 (19%)

Query: 56   RGEQGTPGPPG------PAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSAV--- 105
            +G  G PGPPG      P GP+G  GP G PG PG  G+PG QG PG  G  GP      
Sbjct: 615  KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674

Query: 106  -GKPGVPGLPGK------PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI------ 152
             GKPG+PG+PG       PG+ GP G KG+ GP+G  GP G PGP G+ G  GI      
Sbjct: 675  QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734

Query: 153  -------------------------SVPGKPGQQGP---------TGAPGPRGFPGEKGA 178
                                      VPG  G+ GP         TG PGP G  GEKG 
Sbjct: 735  KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794

Query: 179  ------PGVPGMNGQKGEMGY----GAPGRPGERGLPGPQGPTGPSGPPGV-GKRGENGV 227
                  PG PG  G KG +G+    GA G  G RGL G  GP G  GP G  G+RG  G 
Sbjct: 795  LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854

Query: 228  PGQPGIKG------------DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQP 275
             G+ G KG            +RG PG  GP G PGP+GPPG  G +G+  PG  G  G+ 
Sbjct: 855  TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL--PGHPGQRGEV 912

Query: 276  GIPGTKGLPGAPGIAGP---------------PGPPGF-GKPGLPGLKGERGPAGLPGGP 319
            G  G  G PG PG+ GP               PGPPG  G+ GLPG  G+ G  G PG P
Sbjct: 913  GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972

Query: 320  GAKGEQGPAGL---PGK---PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYP 373
            GA G+ GPAGL   PG+   PG  G PG  G +GP G PG  G PG +G  G  GP G P
Sbjct: 973  GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP 1032

Query: 374  GAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMP 433
            G  G +G PG+ G+ G PG+ G  GP G  G+ GP G PG  GPPG+ G  G  G  G P
Sbjct: 1033 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1092

Query: 434  GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI----ATKGLNGPT 489
            G  G  G +G  G PG  GPIGP G PG  G+ G+PG+ GP G  G      T+G NGP 
Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1152

Query: 490  GP------PGPPGPRGHSGEPGLPGPPGPPGPPGQA--------VMPEGFIKAGQRPSLS 535
            GP      PGP G +G +G+ G  GPPGPPGP G A          P G +     P   
Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1212

Query: 536  GTPLVSANQGVTGMP 550
            G P  S + G+ G P
Sbjct: 1213 GEPGESGSPGIQGEP 1227



 Score =  427 bits (1098), Expect = e-119
 Identities = 250/565 (44%), Positives = 284/565 (50%), Gaps = 106/565 (18%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
            RG QG  GPPG AG RG  G  G  G PG     G  G  G PGLPG  G    G  G  
Sbjct: 522  RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHR--GDTGAQ 579

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPG---PRG---PPGPPGIPGPAGI------------- 152
            GLPG PGE G  G  G++GP GLPG   PRG   P GPPGIPGP G+             
Sbjct: 580  GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 639

Query: 153  ---SVPGKPGQQG---------PTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY----GAP 196
                 PG PGQQG         P GA GP G  G +G PG+PGM G  G  G+    G P
Sbjct: 640  GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPP 699

Query: 197  GRPGERGLPGPQGPTGPSGPPGV----------GKRGENGVPGQPGIKGDRGFPGEMGPI 246
            G  G +G  GPQGP G  GP GV          G +GE G  G PG KGD G  G+ G +
Sbjct: 700  GTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEV 759

Query: 247  GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG----FGKPG 302
            G PG +G  G  GP+G  + G  G PG PG+ G KG  G PG+ G PG  G     G PG
Sbjct: 760  GVPGSRGEDGPEGPKG--RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 817

Query: 303  LPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKG 362
             PG  GE+G  GL G  G +GE+GP G  G+ G  G  G  G +G  G  G HG PG +G
Sbjct: 818  FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 877

Query: 363  ETGPAGPAGYPGAKGERGSPGSDGKPGYPGK---------------PGLDGP-------- 399
              GP GP G+PG KG  G PG DG PG+PG+               PG+ GP        
Sbjct: 878  LPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETG 937

Query: 400  ----KGNPGLPGPKGDPGVGG------------PPGLPGPVGPAGAKGMPGHNGEAGPRG 443
                +G+PG PGP G+ G+ G            PPG PG  GPAG +G PG  G  G  G
Sbjct: 938  PMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAG 997

Query: 444  APGIPGTRGPIGPPGIPGFPGSK---------GDPGSPGPPGPAGIA-TKGLNGPTGPPG 493
             PG+ G  GP GPPG  G PG +         G PG PGP GP G A  KG+ G  GP G
Sbjct: 998  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 1057

Query: 494  PPGPRGHSGEPGLPGPPGPPGPPGQ 518
            P G  G  G  GLPGP GPPG  G+
Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGE 1082



 Score =  424 bits (1091), Expect = e-118
 Identities = 267/614 (43%), Positives = 294/614 (47%), Gaps = 115/614 (18%)

Query: 50   SKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPG---PPGP 102
            S G    G  G  G PGP GP G PGP GPPG PG     G PG +GE G  G   PPGP
Sbjct: 864  SGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923

Query: 103  SAV-------------------GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143
              V                   G PG PG  G PG  G  G KGD GP G PG  GP G 
Sbjct: 924  PGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGL 983

Query: 144  PGIPGPAGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGR 198
             G PG  G+      PG  G +GP+G PGP G PGE+GA G  G  G  G  G  G PG 
Sbjct: 984  RGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGA 1043

Query: 199  PGERGLPGPQGPTGPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP 251
             GE+G+PG +GP GP+G  GV       G  G  GV G+ G KG+ G PG+ G  G  G 
Sbjct: 1044 AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1103

Query: 252  QGPPGERGPEG-IGKPGAAGAPGQPGIPG------TKGLPGAPGIAGPPGPPGF-GKPGL 303
             GPPG  GP G +G+PGAAGA G+PG  G       KG  G  G  GPPGP G  G PG 
Sbjct: 1104 HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP 1163

Query: 304  PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG---NMGPQGPKGIPGSHGLPGP 360
             G KGE G  G  G PG  G +GPAG  G  G  GPPG   N+GP G KG PG  G PG 
Sbjct: 1164 SGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGI 1223

Query: 361  KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPG---LPGPKGDPGVGGP 417
            +GE G  GP G  G KGE G PG  G PG  G  G DGPKGNPG    PG  G PG GGP
Sbjct: 1224 QGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGP 1283

Query: 418  ---------------PGLPGPVGPAGAKGMPGHNGEAGPRGAPG---------------- 446
                           PG PG  GP G  G PG  G+ GP G+PG                
Sbjct: 1284 RGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1343

Query: 447  --IPGTRGPIGPPG---------IPGFPGSKGDPGSPG------PPGPAG---------- 479
               PG  GP+GP G         + G PGS G  G PG      PPGP G          
Sbjct: 1344 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1403

Query: 480  ---IATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP--EGFIKAGQRPSL 534
                  KG  G  G  GPPG +G  G+ GLPGP G PG  G+  +P   G I  G  P L
Sbjct: 1404 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1463

Query: 535  SGTPLVSANQGVTG 548
             G       +G TG
Sbjct: 1464 PGPAGPKGAKGATG 1477



 Score =  392 bits (1006), Expect = e-109
 Identities = 246/611 (40%), Positives = 285/611 (46%), Gaps = 119/611 (19%)

Query: 55  VRGEQGTP----------GPPGPAGP---------RGHPGPSGPPGKPGY-GSPGLQGEP 94
           ++GE+G P          GPPGP GP         +G+PGP G PG+ G  G  GL G  
Sbjct: 381 LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 440

Query: 95  GLPGPPG--------------------------------------------------PSA 104
           G PGPPG                                                  P  
Sbjct: 441 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 500

Query: 105 VGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPT 164
           +G+PG PGL G+ G+ GP GP+G  G  G PG  G  G  G  G  G  +PG PG +G  
Sbjct: 501 LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG--MPGDPGVKGDR 558

Query: 165 GAPGPRGFPGEK---------GAPGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPT 211
           G  G  G PGEK         G PG PG +G++G+ G     G PG  G RGL GP+GP 
Sbjct: 559 GFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPP 618

Query: 212 GPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-I 263
           G  GPPGV       G +G  G  G+PG  G +G PG  G  GP G  GP GE+GP+G  
Sbjct: 619 GIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKP 678

Query: 264 GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKG 323
           G PG  G+ G PG PG +G PG  G  GP GP   G  G PG +G +G  G+ G  G KG
Sbjct: 679 GLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQ--GPLGYPGPRGVKGVDGIRGLKGHKG 736

Query: 324 EQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPG 383
           E+G  G PG  G  G  G+ G  G  G  G  G  GPKG TGP G  G PG  GE+G  G
Sbjct: 737 EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 796

Query: 384 SDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGP---VGPAGAKGMPGHNGEAG 440
             G PGYPG+ G  G  G PG PG  G+ G  G  G  GP    GP G +G  G  G  G
Sbjct: 797 VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATG 856

Query: 441 PRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATK-------------GLNG 487
             GA G  G  GP GPPG  G PG +G  G PGP GP G   K             G  G
Sbjct: 857 KSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQG 916

Query: 488 PTGPPGPPGPRGHSGEPGLPGP------PGPPGPPGQAVMPEGFIKAGQR--PSLSGTPL 539
            TGPPGPPG  G  G  G  GP      PGPPGPPG+  +P    K G +  P   G P 
Sbjct: 917 KTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976

Query: 540 VSANQGVTGMP 550
                G+ G P
Sbjct: 977 KDGPAGLRGFP 987



 Score =  383 bits (984), Expect = e-106
 Identities = 237/529 (44%), Positives = 268/529 (50%), Gaps = 79/529 (14%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------------GSPGLQGEPGLPGPPGPS 103
            GE+G  G  GP GP G PGP GPPG  G              G  G+QG  GLPGP GP 
Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 1077

Query: 104  AV-GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQG 162
             V G+ G  G  G PG++G  G KG+ GP G PGP GP G PG  G  G   PG  G QG
Sbjct: 1078 GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADG--EPGARGPQG 1135

Query: 163  PTGAPGP---RGF---PGEKGAPGVPGMNGQKGEMG----YGAPGRPGERGLPGPQGPTG 212
              GA G    RGF   PG  G  G+PG +G+KGE G     G PG PG RG  GP G  G
Sbjct: 1136 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1195

Query: 213  PSGPPG-------------VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG 259
            P GPPG              G+ G  G+ G+PG+KG RG  GE G  G PG  GPPG +G
Sbjct: 1196 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1255

Query: 260  PEGI----GKPGAAGAPGQPGIPG---------TKGLPGAPGIAGPPGPPG-FGKPGLPG 305
            P G     G PG  G PG PG PG          KG  G  G  G PG PG  G+ G PG
Sbjct: 1256 PTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPG 1315

Query: 306  LKGERGPAGLPG------GPGAKGEQGPAGLPGKPGLTGPPGNMGPQGP---KGIPGS-- 354
              G+RGPAG PG      G GAKG+ G  G PGK G  GP G  G  GP   +G+PGS  
Sbjct: 1316 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1375

Query: 355  -HGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGP------KGNPGLPG 407
              G PG  G+ GP GP G PG  G RG  G+ G+ G+PG  GL GP      KG+ GLPG
Sbjct: 1376 QQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1435

Query: 408  PKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKG 467
            P+G PG  G  G+PG  GP G  G PG  G AGP+GA G  G  GP G  G+ G PG  G
Sbjct: 1436 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPG 1495

Query: 468  DPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP--GPPGPPG 514
             PG    P P  +  K            G R    +  +P  G PG PG
Sbjct: 1496 PPGEVIQPLPIQMPKKTRR------SVDGSRLMQEDEAIPTGGAPGSPG 1538



 Score =  370 bits (950), Expect = e-102
 Identities = 242/631 (38%), Positives = 285/631 (45%), Gaps = 122/631 (19%)

Query: 34  PLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGP----------------AGPRGHPGPS 77
           PL   +T   +P T         GE GT  P GP                 GP      +
Sbjct: 310 PLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGP-ALSAET 368

Query: 78  GPPGKPGYGSPGLQGEPGLP----------GPPGPSAVGKPGVPGLPGKPGERGPYGPKG 127
              G   +G  GL+GE G P          GPPGP      G  GL G PG +G  GP G
Sbjct: 369 AHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPE-----GPAGLIGPPGIQGNPGPVG 423

Query: 128 DVGPAGLPGPRGPPGPPGIPGPAGISV------PGKPGQQGPT----------------- 164
           D G  G PG  G PG  G PGP G S+          G +GP                  
Sbjct: 424 DPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARL 483

Query: 165 ---GAPGPRGF---PGEKGAPGVPGMNGQKGEMG----------YGAPGRPGERGLPGPQ 208
              G PGP G+   PG  G PG PG+ G+ G++G           G PG+ G RG  G  
Sbjct: 484 ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 543

Query: 209 GPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPP------------GPQGPP 255
           G  G  G PGV G RG +G+PG PG KG RG  G  G  GPP            GP+G P
Sbjct: 544 GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 603

Query: 256 GERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKPGLPGLKGERGPA 313
           GE GP G +G  G  G PG PG+ G  G  G  G  GP G PG  G+ G PG +G  GP 
Sbjct: 604 GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQ 663

Query: 314 GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYP 373
           G  G  G KG QG  GLPG PG  GPPG+ G +GP G  G+ G  GP+G  G  GP G  
Sbjct: 664 GAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVK 723

Query: 374 GA------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPA 427
           G       KG +G  G DG PG+ G  G+ G +G  G+PG +G+ G  GP G  GP G  
Sbjct: 724 GVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDP 783

Query: 428 GAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGS------------PGPP 475
           G  G+ G  G+ G  G PG PG +GP G  G PGFPG+ G+ G+             GP 
Sbjct: 784 GPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843

Query: 476 GPAG----------IATKGLNGPTGPPGPPGPR---GHSGEPGLPGPPGPPGPPGQAVMP 522
           GP G             KG +G  GP GPPG R   G  G  G PGP GPPGPPG+  +P
Sbjct: 844 GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLP 903

Query: 523 -----EGFIKAGQRPSLSGTPLVSANQGVTG 548
                 G +    +    G P V   QG  G
Sbjct: 904 GHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 934



 Score =  268 bits (685), Expect = 1e-71
 Identities = 177/433 (40%), Positives = 199/433 (45%), Gaps = 89/433 (20%)

Query: 192 GYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGP 251
           GYG   R      P     T  SG    G RG  G  G+P +      PG +   GPPGP
Sbjct: 349 GYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLE----PGMLVE-GPPGP 403

Query: 252 QGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPG-----PPGFGK----- 300
           +GP G  GP GI G PG  G PG+ G PG  GLPG+ G  GPPG     P  FG      
Sbjct: 404 EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 463

Query: 301 -------------------------PGLPGLKGERGPAGLPGGPGAKGEQG---PAGLPG 332
                                    PG  G  G  GP G PG PG KGE G   P G  G
Sbjct: 464 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 523

Query: 333 KPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPG 392
             GLTGPPG  G +G  G  G+ G+PG  G  G  G  G PG  GE+G  G  G  G PG
Sbjct: 524 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 583

Query: 393 KPGLD---------GPKGNP------GLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNG 437
            PG D         GP+G P      GL GPKG PG+ GPPG+ G  GP G KG  G  G
Sbjct: 584 PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 643

Query: 438 EAGPRGAPGIPGT---------------RGPIGPPGIPGFPGSKGDPGSPGPPGPAGIAT 482
           E GP G  G PGT               +GP G PG+PG PGS G PG PG  GP G  T
Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPG--T 701

Query: 483 KGLNGPTGPPGP---PGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPL 539
           KG  GP+GP GP   PGPRG  G  G+ G  G  G  G+    +GF      P   G   
Sbjct: 702 KGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGE----DGF------PGFKGDIG 751

Query: 540 VSANQGVTGMPVS 552
           V  ++G  G+P S
Sbjct: 752 VKGDRGEVGVPGS 764


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  428 bits (1101), Expect = e-120
 Identities = 264/631 (41%), Positives = 309/631 (48%), Gaps = 137/631 (21%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPG------PSGPPG 81
            P G  G LP T T  F P+         +GE+G PG PG  G +G PG      P+GPPG
Sbjct: 844  PAGPPG-LPGT-TSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901

Query: 82   KPG----YGSPGLQGEPGLPG---PPGPS----AVGKPGVPGLPGKPGERGPYGPKGDVG 130
              G    +G+PG  G PG PG    PGPS    +VG PG+ G PGK GERG  G  G+ G
Sbjct: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEG 961

Query: 131  PAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRG------------------- 171
              G  GPRG PG PG+PGP G    G+PG +G  G PGP G                   
Sbjct: 962  SPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQ 1021

Query: 172  -FPGEKGAPGVPGMNGQKGEMGYGAPG------------RPGERGLPG---PQGPTG--- 212
               G++GAPG+PG  G +G+ G G  G             PG RGLPG   PQGP G   
Sbjct: 1022 CVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDG 1081

Query: 213  ------------------------------------PSGPPGV----GKRGENGVPGQPG 232
                                                P GPPG+    G +G+ GVPG+PG
Sbjct: 1082 APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPG 1141

Query: 233  IKGDRGFPGEMGPIGPPGP------QGPPGERGPEG-IGKPGAAGAPGQPGI---PGTKG 282
             +G  G  GE GP G PGP      QG  GERG +G +G+ G  G PG PG    PG  G
Sbjct: 1142 REGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPG 1201

Query: 283  LPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
             PGA GIAG  GPPG  G PG  G  G +GP+GLPG PG +G++G  G PG      PPG
Sbjct: 1202 PPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPG------PPG 1255

Query: 342  NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
              G  G  G+PG  G  GP G  G  G +G PG +GE G+ G  G+ G PGK G  GP G
Sbjct: 1256 EPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTG 1315

Query: 402  NPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPG 461
              G  GP+G PG  G PG PG  GP+G  G  G  GE G  G PG  G RGP G PG  G
Sbjct: 1316 PQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKG 1375

Query: 462  FPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP-------------- 507
             PG +G PG PG PG  G   +G  G  G  GPPG +G  G+PG+P              
Sbjct: 1376 VPGKEGVPGKPGEPGFKG--ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 1433

Query: 508  ----GPPGPPGPPGQAVMPEGFIKAGQRPSL 534
                GP GPPGPPGQ   P      G+ PS+
Sbjct: 1434 PGENGPVGPPGPPGQPGFPG---LRGESPSM 1461



 Score =  426 bits (1094), Expect = e-119
 Identities = 269/655 (41%), Positives = 308/655 (47%), Gaps = 170/655 (25%)

Query: 51   KGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGL-------------- 96
            KG A  GE+G+PGP GP G  G PG  GPPGK   G PGL+G PGL              
Sbjct: 954  KGAA--GEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVR 1011

Query: 97   ---------------------PGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLP 135
                                 PG PG  + G PG+ G+ G PG  GP G KG  G  GLP
Sbjct: 1012 GSENCALGGQCVKGDRGAPGIPGSPG--SRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLP 1068

Query: 136  GPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF--PGE-------------KGAPG 180
            G  GP GP G  G      PG PG++GP G PG      PG+              G PG
Sbjct: 1069 GFPGPQGPAGRDG-----APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPG 1123

Query: 181  VPGMNGQKGEMGY-GAPGRPGERGLPGPQGPTGPSGPPGV----GKRGENGVPGQPGIKG 235
            +PG+ G KG+ G  G PGR G  G  G  GP G  GPPG+    G +GE G  G+ G KG
Sbjct: 1124 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 1183

Query: 236  DRGFPGEMGPIGPPGPQGPP------GERGPEGI-------GKPGAAGAPGQPGIPGTKG 282
            D+G PG  G +GPPG  GPP      G  GP GI       G PG  G  G PGIPG +G
Sbjct: 1184 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 1243

Query: 283  LPGAPGIAGPPGPPG-FGKPGLPGLKGERGPAGL------PGGPGAKGEQGPAGLPGKPG 335
              G  G  GPPG PG  G+PGLPG +G RGP G        G PG +GE G  GLPG+ G
Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEG 1303

Query: 336  L------TGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE----------- 378
            L      TGP G  GPQGP+G PG +G PG  GE GP+G  G  G+KGE           
Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLG 1363

Query: 379  -RGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNG 437
             RG PG  G+ G PGK G+ G  G PG  G +GDPG+ G  G PG  G  G  G+PGH G
Sbjct: 1364 PRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKG 1423

Query: 438  EAGPRGAPGIPGTRGPIGPPGIPGFPG--------------------------------- 464
              G  G  G+PG  GP+GPPG PG PG                                 
Sbjct: 1424 HTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYL 1483

Query: 465  -----------SKGDPGSPGPPGPAGIATK-------------GLNGPTGPPGPPGPRGH 500
                       S+G PG PGPPG  G+  +             GL GP+GP GP G RG 
Sbjct: 1484 LAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGA 1543

Query: 501  SGEPGLP-----GPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
             G+PG P     G  GPPG PGQ   P G+ K G    L G P      G  G P
Sbjct: 1544 KGDPGAPGVGLRGEMGPPGIPGQPGEP-GYAKDG----LPGIPGPQGETGPAGHP 1593



 Score =  419 bits (1078), Expect = e-117
 Identities = 268/682 (39%), Positives = 311/682 (45%), Gaps = 191/682 (28%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPG-------------P 102
            G  G PGPPGP GP G  GP+GPPG PG  G PG +GE GLPG PG             P
Sbjct: 738  GFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 797

Query: 103  SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRG---------PPGPPGIPGPAGIS 153
               G+ G+PG PG PG RG  G +G+ G  GLPG +G         P GPPG+PG   + 
Sbjct: 798  GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 857

Query: 154  VP--------------------------GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQ 187
             P                          G+PG+ GP G  GP G  G++GA G PG  G 
Sbjct: 858  TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGN 917

Query: 188  KGEMGY-------------------GAPGRPGERG---------LPGPQGPTGPSG---- 215
             G  G+                   G PG+ GERG          PGP GP G  G    
Sbjct: 918  PGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGL 977

Query: 216  --PPGVGKRGENGVPGQPG--------------------------IKGDRGFPG------ 241
              PPG GK GE G+ G PG                          +KGDRG PG      
Sbjct: 978  PGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPG 1037

Query: 242  -----EMGPIGPPGPQGPPGERGPEGI-------GKPGAAGAPGQPGIPGTKGLPGAPGI 289
                  +G  GPPGP GPPG++G  G        G  G AG  G PG PG +G PG PG+
Sbjct: 1038 SRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGL 1097

Query: 290  AG------------------PPGPPGFGKPGLPGLKGERGPAGLPGGPGA---KGEQGPA 328
            +                   PPGPPG   PGLPG KG++G  G PG  G    KGE GP 
Sbjct: 1098 SSLLSPGDINLLAKDVCNDCPPGPPGL--PGLPGFKGDKGVPGKPGREGTEGKKGEAGPP 1155

Query: 329  GLPGKPGLTGPPGN---------MGPQGPKGIPGSHGLPGPKGETGP---------AGPA 370
            GLPG PG+ GP G+         +G +G +G PG  G  GP G  GP         AGP 
Sbjct: 1156 GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 1215

Query: 371  GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK 430
            G  G+ G+ G PG  G  G PG PG +G +G  G PGP G+PG  G PGLPGP G  G  
Sbjct: 1216 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPP 1275

Query: 431  GMPGHNGEA---GPR---GAPGIPGTR------------GPIGPPGIPGFPGSKGDPGSP 472
            G  GH G++   GPR   GA G+PG              GP GP G  G PG  G PGSP
Sbjct: 1276 GFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSP 1335

Query: 473  GPPGPAGI----ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKA 528
            G PGP+G      +KG NG  G PG  GPRG  GEPG  G PG  G PG+   P GF   
Sbjct: 1336 GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP-GFKGE 1394

Query: 529  GQRPSLSGTPLVSANQGVTGMP 550
               P + G       +G  G P
Sbjct: 1395 RGDPGIKGDKGPPGGKGQPGDP 1416



 Score =  407 bits (1047), Expect = e-113
 Identities = 258/583 (44%), Positives = 290/583 (49%), Gaps = 80/583 (13%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPG---PAGPRGHPGPSGPPGKPG 84
            P G  GP          P+    KG   +G  G PGPPG     G RG PG  G PG PG
Sbjct: 506  PVGAPGPKGEKGDVGIGPFGQGEKG--EKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPG 563

Query: 85   -YGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143
              G  G QG PGLPGPPG     + G PGL G+ GE+G  G KG+ G  G PG  G  G 
Sbjct: 564  EVGMRGPQGPPGLPGPPG-----RVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618

Query: 144  PGIPGPAGISVP-GKPGQQGPTGAPGPRGF----PGEKGAPGVPGMNGQKGEMGYGAPGR 198
             G PGP+G++ P G+ G  GP G PG  G      G KG  G PG  G +G     APG 
Sbjct: 619  QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQG-----APGP 673

Query: 199  PGERGLPGPQGPTGPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGE 257
            PG RG  GP+G  GP G  G+ GK+G+ G PG PG+ G +G PG  G  GPPGP G PG 
Sbjct: 674  PGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGL 733

Query: 258  RGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGL 315
             G  G  GKPG  G  G PG  G  G PG PG  G PG  G  G PG PGL+GE G  GL
Sbjct: 734  PGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGL 793

Query: 316  PGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGA 375
             G PG KGE G  G PG PG+ G  G+ G +G  G+PG  G  G KGE GPAGP G PG 
Sbjct: 794  AGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGT 853

Query: 376  ----------------KGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD------PG 413
                            KGE+G PG  G+PG  G+PG  GP+G  G PG KG       PG
Sbjct: 854  TSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG 913

Query: 414  VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGS---KGDPG 470
              G PG PG VG  G  G PG  G  G RG PG  G RG  G  G  G PG    +GDPG
Sbjct: 914  AAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPG 973

Query: 471  S---PGPPGPAGIATKGLNGPTGPPGPPGP--------------------RGHSGEPGLP 507
            +   PGPPG       GL G  G PGP G                     +G  G PG+P
Sbjct: 974  APGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIP 1033

Query: 508  GPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G PG  G PG  V       AG  P  SG P    + G  G+P
Sbjct: 1034 GSPGSRGDPGIGV-------AGP-PGPSGPPGDKGSPGSRGLP 1068



 Score =  407 bits (1047), Expect = e-113
 Identities = 250/578 (43%), Positives = 285/578 (49%), Gaps = 108/578 (18%)

Query: 44   IPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-------YGSPGLQGEPGL 96
            IP +  S+G    G  G PGP GP G +G PG  G PG PG        G+PG  GE G 
Sbjct: 1032 IPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGP 1091

Query: 97   PGPPGPSAV-------------------GKPGVPGL---------PGKPGERGPYGPKGD 128
            PG PG S++                   G PG+PGL         PGKPG  G  G KG+
Sbjct: 1092 PGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 1151

Query: 129  VGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQK 188
             GP GLPGP G  GP G  G  G    G+ GQ+G  G PG  GF G  G PG PG +G  
Sbjct: 1152 AGPPGLPGPPGIAGPQGSQGERG--ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 1209

Query: 189  GEMG-YGAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKGDRGFPGEM 243
            G  G  G  G PG+ G PGPQGP+G  G PG     G+ G+ G PG+PG  G+ G PG  
Sbjct: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE 1269

Query: 244  GPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-FGKP 301
            G  GPPG +G  G+ G  G  G+ GA G PGQ G+PG  G  G  G  GP GP G  GK 
Sbjct: 1270 GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKN 1329

Query: 302  GLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPK 361
            G PG  GE GP+G PG  G+KGE G  GLPG  G  GPPG     G KG+PG  G+PG  
Sbjct: 1330 GSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE---PGEKGVPGKEGVPGKP 1386

Query: 362  GETGPAGPAGYPGAKGERGSPGSDGKPGYPGKP------GLDGPKGNPGLPGPKGDPGVG 415
            GE G  G  G PG KG++G PG  G+PG PG P      GL GP+G PG  GP G PG  
Sbjct: 1387 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 1446

Query: 416  GPPGL-----------------------------------------------PGPVGPAG 428
            G PG                                                PGP GP G
Sbjct: 1447 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 1506

Query: 429  AKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP--------GPPGPAGI 480
              G+PG  G  G  G PG  G  GP GP G  G  G+KGDPG+P        GPPG  G 
Sbjct: 1507 KDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQ 1566

Query: 481  ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ 518
              +      G PG PGP+G +G  G PG PGPPGPPGQ
Sbjct: 1567 PGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604



 Score =  342 bits (876), Expect = 9e-94
 Identities = 215/499 (43%), Positives = 239/499 (47%), Gaps = 64/499 (12%)

Query: 99  PPGPSAVGKPGVPGLPGKPGERGPYGPKGDVG---------PAGLPGPRGPPGPPGIPGP 149
           P GP  V     P  P  P +R P      +G         PAG  G  G  GP G+PGP
Sbjct: 439 PSGPCQVTVVTEPP-PPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGP 497

Query: 150 AGISVPGKPGQQGPTGAPGPRGFPGEKG-APGVPGMNGQKGEMGY-GAPGRPGERGLPGP 207
            G       G  GP GAPGP+G  G+ G  P   G  G+KG +G  G PGR G +G+ G 
Sbjct: 498 KG-----DIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGE 552

Query: 208 QGPTGPSGPPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GK 265
            G  G  G PG VG RG  G PG PG  G  G PG  G  G  G +G  GERG +G  GK
Sbjct: 553 PGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGK 612

Query: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF--------GKPGLPGLKGERGPAGLPG 317
           PG  G  G+PG  G  G  G  G  GP GPPG         G  G  G  G RG  G PG
Sbjct: 613 PGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG 672

Query: 318 GPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGL---PGPKGETGPAGPAGYPG 374
            PGA+G  GP G  G PGL G  G  G  GP GIPG  GL   PGP G  GP GP G PG
Sbjct: 673 PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732

Query: 375 AKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPG 434
             GE G PG  G PG  G PG DGP G PG PG KG+PG  G  GLPG          PG
Sbjct: 733 LPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK---------PG 783

Query: 435 HNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI-------ATKGLNG 487
             GE G +G  G PG +G  G PG PGFPG +G+ G  G  G  G+         KG  G
Sbjct: 784 LRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 843

Query: 488 PTGPPGPP----------------GPRGHSGEPGLPGPPGPPGPPGQ--AVMPEGFIKAG 529
           P GPPG P                GP+G  G+PGLPG PG  G PG+     P G   A 
Sbjct: 844 PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903

Query: 530 QRPSLSGTPLVSANQGVTG 548
            +    G P  + N G  G
Sbjct: 904 GQEGAHGAPGAAGNPGAPG 922



 Score =  281 bits (718), Expect = 2e-75
 Identities = 172/408 (42%), Positives = 199/408 (48%), Gaps = 83/408 (20%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------GSPGLQGEPGLPGP-------- 99
            ++G  G  GPPGP GP G PG  G  GK G        G PG  GEPGLPGP        
Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276

Query: 100  ----------PGP----SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG 145
                      PGP     A+G PG  GLPGK G+ GP GP+G  GP G PG  G PG PG
Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 1336

Query: 146  IPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGL 204
             PGP+G   PG+ G +G  G+PG  GF G +G PG PG  G  G+ G  G PG PG +G 
Sbjct: 1337 EPGPSG--TPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 1394

Query: 205  PGPQGPTGPSGPPG-VGKRGENGVPGQPG---IKGDRGFPGEMGPIGPPGPQGPPGERGP 260
             G  G  G  GPPG  G+ G+ G+PG  G   + G +G PGE GP+GPPGP G PG  G 
Sbjct: 1395 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 1454

Query: 261  EG---------------IGKP------------------GAAGAPGQPGIPGTKGLPGAP 287
             G               +GK                    + G PG PG PG  GLPG  
Sbjct: 1455 RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 1514

Query: 288  GIAGPPGPPGFG----KPGLPGLKGERGPAGLPGGPGA--KGEQGPAGLPGKPG------ 335
            G  G PG PG G      G  G KGERG  G PG PG   +GE GP G+PG+PG      
Sbjct: 1515 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1574

Query: 336  --LTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS 381
              L G PG  G  GP G PG  G PGP G+  P+  A +       G+
Sbjct: 1575 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGN 1622



 Score = 99.8 bits (247), Expect = 8e-21
 Identities = 51/112 (45%), Positives = 62/112 (55%), Gaps = 14/112 (12%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116
            G+ G  GP GP GP+G  G  G PG PG G  G  G PG+PG PG     K G+PG+P  
Sbjct: 1524 GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIP-- 1581

Query: 117  PGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG----ISVPGKPGQ-QGP 163
                   GP+G+ GPAG PG  GPPGPPG   P+      S+  +PG  +GP
Sbjct: 1582 -------GPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGNVKGP 1626


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  426 bits (1094), Expect = e-119
 Identities = 255/583 (43%), Positives = 298/583 (51%), Gaps = 101/583 (17%)

Query: 48   IKSKGIAVRGEQGTPGPPGPAGPR---GHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPS- 103
            I  +G  + G +G PGP GP GPR   G PGP GPPG PG    G +G+ G  GPPGP  
Sbjct: 1356 IGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGE 1415

Query: 104  ---AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQ 160
               A G+PG+PGLPG PG +GP GP G  G  G        G PG+PG      PG PG+
Sbjct: 1416 GGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG----DSEDGAPGLPGQ-----PGSPGE 1466

Query: 161  QGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP---GPQGPTGPSGPP 217
            QGP G PG  G  G++G PG  G  G+KGE   G PG  G RGLP   G  G  GP GPP
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGER--GPPGPAGSRGLPGVAGRPGAKGPEGPP 1524

Query: 218  G-VGKRGENGVPGQPG--------IKGDRGFPGEMGPIGP-------------------- 248
            G  G++GE G PG+PG        + G +G  G++GP GP                    
Sbjct: 1525 GPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGD 1584

Query: 249  PGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF---------- 298
            PGP+G PG+RGP  IG  G AG PG  G PG KG PG PG  GP GP G           
Sbjct: 1585 PGPKGDPGDRGP--IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642

Query: 299  ---GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSH 355
               G PGLPG  GERG  G PG  G  GE+G  G PG+ G  G PG+ GP+G +G PG  
Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702

Query: 356  GLPGPKGETGP-AGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGV 414
            G PG   +TGP A   G PG +G+ G  G  G PG PG PG  G +G  G PGP+GDPGV
Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGV 1762

Query: 415  GGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGP 474
             GP G  G  GP G  G  G +G+ G  G  G  G  G  G PG  G PG +G+ G PGP
Sbjct: 1763 RGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP 1822

Query: 475  PGPAGIATK-------GLNGPTGPPGPP---------------------GPRGHSGEPGL 506
             GP G+  K       GLNG  G PG P                     GP+G  G PG+
Sbjct: 1823 SGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGI 1882

Query: 507  PGPPGPPGPPGQAVMP-EGFIKAGQRPSLSGTPLVSANQGVTG 548
             GP GPPG PG    P +GF      P + G      ++G TG
Sbjct: 1883 LGPQGPPGLPGPVGPPGQGF------PGVPGGTGPKGDRGETG 1919



 Score =  417 bits (1072), Expect = e-116
 Identities = 253/570 (44%), Positives = 289/570 (50%), Gaps = 84/570 (14%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG-PSAVGKPGVP 111
            + +RG+ G PG PG  G  G PGP GPPG     + G +G PG  G PG P   G PG P
Sbjct: 1262 MGLRGQVGPPGDPGLPGRTGAPGPQGPPGSA--TAKGERGFPGADGRPGSPGRAGNPGTP 1319

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPG-IPGPAGISVPGKPGQQGPTGAPGPR 170
            G PG  G  G  GP+GD G  G  GP+G PG PG + G  G  +PG+ G  GP+G PGPR
Sbjct: 1320 GAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR 1379

Query: 171  ---GFPGEKGAPGVPG--MNGQKGEMGYG----------APGRPGERGLPGPQGPTGPSG 215
               G PG +G PG+PG  M G KG+ G            APG PG  GLPG  GP GP G
Sbjct: 1380 GPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVG 1439

Query: 216  PPGVGKRGENG--VPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERG-PEGIGKPGAAGAP 272
            PP  GK+GE G    G PG+ G  G PGE GP GPPG  GP G+RG P  +G+ G  G  
Sbjct: 1440 PP--GKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGER 1497

Query: 273  GQPGIPGTKGLPGA---PGIAGPPGPPG-------FGKPGLP--------------GLKG 308
            G PG  G++GLPG    PG  GP GPPG        G+PG P              G KG
Sbjct: 1498 GPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG 1557

Query: 309  ERGPAGLPGGPGAKGEQGPAG--LPGKPGLTGPPGN---------MGPQGPKGIPGSHGL 357
            + GPAG  G  G +GE+GP G  LPG PG  G PG+          GP G  G PG  G 
Sbjct: 1558 DVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGD 1617

Query: 358  PGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGP------KGD 411
            PG  G  GP GP G  G  GE+G  G  G PG PGK G  G +G PG+ GP      +GD
Sbjct: 1618 PGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGD 1677

Query: 412  PGVGGPPGLPGPVGPAGAKGMPGHNG-------------EAGPRGAPGIPGTRGPIGPPG 458
            PG  G  G PG  GP G +G PG  G             E G  G  G  G RGP G PG
Sbjct: 1678 PGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPG 1737

Query: 459  IPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ 518
            +PG PG +G  G  GPPGP G    G+ GP G  G  GP G  G  GL G PG  GP G 
Sbjct: 1738 LPGAPGERGIEGFRGPPGPQG--DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSG- 1794

Query: 519  AVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
               P G       P   G P +   QG+ G
Sbjct: 1795 ---PNGAAGKAGDPGRDGLPGLRGEQGLPG 1821



 Score =  406 bits (1043), Expect = e-113
 Identities = 250/515 (48%), Positives = 273/515 (53%), Gaps = 62/515 (12%)

Query: 49   KSKGIAVRGEQGTPGPPGPAGPRGHP----GPSGPPGKPGY-GSPGLQGEPGLPGPPGPS 103
            K   I   GE+G  G  G  GP+G P    G  GPPG  G  G PG  G PGLPG  G  
Sbjct: 1992 KEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAG-- 2049

Query: 104  AVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGP 163
             VG+ G PG  G+ GE+G  G +G  GP GLPG  GPPGPPG         PG  G+QGP
Sbjct: 2050 GVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGP 2109

Query: 164  TGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGVGKR 222
                     PG KGA G PG NG +G  G  G PG  G+RG PGP+G  G  G P  G+R
Sbjct: 2110 ---------PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLP--GER 2158

Query: 223  GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIP--G 279
            G  G  G+PG++G RG PG +G  G PGP G PG  GP G  G  G  G PG+ G P  G
Sbjct: 2159 GMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRG 2218

Query: 280  TKGLPGAPGIAGPPGPPGF----GKPGLPGLKGERGPAGLPGGPGAK---GEQGPAGLPG 332
              G  GA G+ GPPGP G     G PGLPG  GE G  G PG  GA    G++G  G+PG
Sbjct: 2219 LTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPG 2278

Query: 333  KPGLTGPPGNMGPQGPKGIPGSH--GLPGPKGETG-PAGPA----GYPGAKGERGSP--- 382
             PGL GP G  G  GP G PG    GLPG KGE G P G A    G PGAKG+RG P   
Sbjct: 2279 SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPR 2338

Query: 383  ---GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAK--------- 430
               G  G+ G PG PG DG KG PG  G KGDPGV G PG PGP GP G K         
Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGLP 2397

Query: 431  ------GMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKG 484
                  G PG  G  G  G PG  G RG  GPPG  G PG  G PG PG  GP G    G
Sbjct: 2398 GAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPG--ASG 2455

Query: 485  LNGPTGPPGP--PGPRGHSGEPGLPGPPGPPGPPG 517
            L G  G PG   PGPRG  GEPG+ G  G PG  G
Sbjct: 2456 LKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEG 2490



 Score =  405 bits (1040), Expect = e-113
 Identities = 257/616 (41%), Positives = 293/616 (47%), Gaps = 123/616 (19%)

Query: 47   TIKSKGIAVRGEQGTP---------------------GPPGPAGPRGHPGPSGPPGKPGY 85
            ++   G  + GEQG P                     G PG  G RG PGP G  G PG 
Sbjct: 2095 SVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGL 2154

Query: 86   ----GSPGLQGEPGLPGPPG-PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGP 140
                G  G +G+PGL GP G P  VG  G PG PG PG  GP GP+G  G  G PG  GP
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGP 2214

Query: 141  PGPPGIPGPAG-ISVPGKPGQQ---GPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGA 195
            PG  G+ GP G + +PG PG     GP G+PG  G  GE G PG PG +G  G+ G  G+
Sbjct: 2215 PG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGS 2273

Query: 196  PGRPGERGLPGPQGPTGPSGPPGV---------GKRGENGVP--------GQPGIKGDRG 238
            PG PG  GLPGP GP G  GP G          G +GE G P        G+PG KGDRG
Sbjct: 2274 PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRG 2333

Query: 239  FPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQP--GIPGTKGLPGAPGIAGPPGP 295
             PG  G  G  G  G PG+ G +G  G PG  G  G P  G+PG+ G PG PG+ G  G 
Sbjct: 2334 LPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393

Query: 296  PGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGS 354
            PG  G PG+ G  G+ GP G  G PG  GE+G AG PG+ G+ GP G  GP G  G PG+
Sbjct: 2394 PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453

Query: 355  HGLPGPKGETGPAGPAGYPGAKGERGSP---GSDGKPGYPGKPGLDGPKGN--------- 402
             GL G KG+ G     G PG +GERG P   G DG+PG  G  GL GP G+         
Sbjct: 2454 SGLKGDKGDPG----VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGD 2509

Query: 403  -------------------PGLPGPKGDPGVGGPPGLPGPVGPAGAKGMP---GHNGEAG 440
                               PG  G KGD G  GP GL G  GP G  G P   G  GE G
Sbjct: 2510 VGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPG 2569

Query: 441  PRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI-------------------- 480
             +G+ G+PG RG +GP G PG  G  GDPGSPG  G  GI                    
Sbjct: 2570 DKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERG 2629

Query: 481  --------ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRP 532
                      KG  G  GPPG PG  GH GE G PG PG  G PG+    EG I      
Sbjct: 2630 VKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGK----EGLIGPKGDR 2685

Query: 533  SLSGTPLVSANQGVTG 548
               G P    +QG  G
Sbjct: 2686 GFDGQPGPKGDQGEKG 2701



 Score =  404 bits (1037), Expect = e-112
 Identities = 252/575 (43%), Positives = 287/575 (49%), Gaps = 117/575 (20%)

Query: 56   RGEQGTPGPPGPAGPRGHPGPSGPPGKPGY------------------------GSPGLQ 91
            +G+ G  GPPGP GP G PGP GPPG PG                         G PGL 
Sbjct: 1367 KGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLP 1426

Query: 92   GEPGLPGPPGP------------SAVGKPGVPGLPGKPGERGPYGPKGDVGPAG---LPG 136
            G PG PGP GP            S  G PG+PG PG PGE+GP GP G +GP G    PG
Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPG 1486

Query: 137  P---------RGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPG---- 183
            P         RGPPGP G  G  G++  G+PG +GP G PGP G  GEKG PG PG    
Sbjct: 1487 PLGEAGEKGERGPPGPAGSRGLPGVA--GRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544

Query: 184  -------MNGQKGEMG----YGAPGRPGERGLPGP--QGPTGPSGPPGVGKRGENGVPGQ 230
                     G+KG++G     GA G  GERG PG    G  GP G PG   RG  G+ G+
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPG--DRGPIGLTGR 1602

Query: 231  PGIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGT---KGLPGA 286
             G  GD G PGE G  G PGP GP G RG +G +G+ G  G PG PG+PG    +GL GA
Sbjct: 1603 AGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGA 1662

Query: 287  PGIAGPPGPPGF----------GKPGLPGLKGERGPAGLPG--------GPGAK------ 322
            PG+ GP G  G           G PG  G KG+RG  G PG        GPGA+      
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPG 1722

Query: 323  --GEQGPAGLPGKPGLTGPPGNMG------PQGPKGIPGSHGLPGPKGETGP------AG 368
              G++GP G  G PGL G PG  G      P GP+G PG  G  G KG+ GP      +G
Sbjct: 1723 DRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 369  PAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPG---LPGPVG 425
              G PGA G  G  G+ GK G PG+ GL G +G  GLPGP G PG+ G PG    PG  G
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 426  PAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGL 485
              G  G PG +G  G +G  G  G  G  GP G  G PG  G  G PG PGP G   +G 
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902

Query: 486  NGPTGPPGPPGPRGHS---GEPGLPGPPGPPGPPG 517
             G  G  GP G RG +   GE GLPG  G  G PG
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPG 1937



 Score =  404 bits (1037), Expect = e-112
 Identities = 254/569 (44%), Positives = 292/569 (51%), Gaps = 75/569 (13%)

Query: 49   KSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGP------PGP 102
            ++ G+   G  G  G  G  G RG  G  GPP     G PG  G PG PGP      PGP
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPP-----GLPGTPGPPGPPGPKVSVDEPGP 2101

Query: 103  SAVGKPGVPGL---PGKPGERGPYGPKGDVGPAGLPGPRGPPGP------PGIPGPAGIS 153
               G+ G PGL    G+PG  G  GPKGD G  G+ G RG PGP      PG+PG  G++
Sbjct: 2102 GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMA 2161

Query: 154  VP-GKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGER--------- 202
             P GKPG QGP G PGP G  G+ G PG PG+ G  G  G  G  G PGE          
Sbjct: 2162 GPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTG 2221

Query: 203  -----GLPGPQGPT---GPSGPPGV-GKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG 253
                 GLPGP GP+   GP G PG+ G+ GE G PG PG  G  G  G+ G  G PG  G
Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281

Query: 254  PPGERGPEGIGKPGAAGAPGQP--GIPGTKGLPGAPG-----IAGPPGPPG-FGKPGLPG 305
             PG  GP+  G+PG  GAPGQ   G+PG KG  GAPG     + G PG  G  G PG  G
Sbjct: 2282 LPGPVGPK--GEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRG 2339

Query: 306  LKGERGPAGLPGGPGAKGEQGP-----------AGLPGKPGLTGPPGNMGPQGPKGIPGS 354
             KGE G AG PG PG  G++G             G+PG PG  GPPG  G  G  G+PG+
Sbjct: 2340 EKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA 2399

Query: 355  HGLPGPKGETGPAGPAGYPGAKGER---GSPGSDGKP---GYPGKPGLDGPKGNPGLPGP 408
             G+ G  G+TGP G  G PG  GER   G PG +G P   G PG PG  GP G  GL G 
Sbjct: 2400 PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGD 2459

Query: 409  KGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGD 468
            KGDPGV G PG  G  G  G +G  G  G+ GPRG  G PG+RG  G  G  G  G KGD
Sbjct: 2460 KGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518

Query: 469  PGSP----GPPGPAGI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMP- 522
             G      GPPGP G     G  GP G  G  GPRG +G+PG  G  G PG  G A +P 
Sbjct: 2519 KGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPG 2578

Query: 523  -EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
              G +    +P  +G P    + G  G+P
Sbjct: 2579 LRGLLGPQGQPGAAGIPGDPGSPGKDGVP 2607



 Score =  400 bits (1029), Expect = e-111
 Identities = 245/536 (45%), Positives = 279/536 (52%), Gaps = 68/536 (12%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPG---L 113
            G  G+PG PGP GP+G PGP+G PG+   G PG +GE G PG      VG+PG  G   L
Sbjct: 2275 GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGL 2334

Query: 114  PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFP 173
            PG  GE+G  G  G+ G  G  G +G PGP G  G  G+ VPG PG  GP G  G  G P
Sbjct: 2335 PGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLP 2394

Query: 174  GEKGAPGV---PGMNGQKGEMGYGAP-------GRPGERGLPGPQGPTGPSG---PPGV- 219
            G  GAPGV   PG  G +GEMG   P       G PG  G+PGP GP GP G   PPG  
Sbjct: 2395 GLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGAS 2454

Query: 220  GKRGENGVPGQ--PGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGI 277
            G +G+ G PG   PG +G+RG PG  G  G PG +GP G  GP     PG+ G  G+ G 
Sbjct: 2455 GLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP-----PGSRGERGEKGD 2509

Query: 278  PGTKGLPGAPG----IAGPPGPPGF-------GKPGLPGLKGERGPAGLPGGPGAKGE-- 324
             G+ GL G  G    I GPPGP G        G  GL G KG RG  G PG  G+KGE  
Sbjct: 2510 VGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPG 2569

Query: 325  -QGPAGLPGKPGLTGP---PGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERG 380
             +G AGLPG  GL GP   PG  G  G  G PG  G+PG +GE G  G  G  G KGERG
Sbjct: 2570 DKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERG 2629

Query: 381  SPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD---PGVGGPPGLPGPVGPAGAKGMPGHNG 437
              G+ G  G  G  G  GP G PGL G KG+   PGV G  G PG  G  G KG  G +G
Sbjct: 2630 VKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDG 2689

Query: 438  EAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIA----------TKGLNG 487
            + GP+G  G  G RG    PGI GFPG  G+ GS GPPGP G             KG  G
Sbjct: 2690 QPGPKGDQGEKGERGT---PGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERG 2746

Query: 488  PTGP--------PGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLS 535
            P G         PG PG RG  G    PGP GP G  G+A + E  I+   R  +S
Sbjct: 2747 PPGERVVGAPGVPGAPGERGEQGR---PGPAGPRGEKGEAALTEDDIRGFVRQEMS 2799



 Score =  390 bits (1001), Expect = e-108
 Identities = 263/640 (41%), Positives = 297/640 (46%), Gaps = 175/640 (27%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGK-------------PG----YGSPGLQGEPGLPGP 99
            G  G+PG  GP G RG PGP GPPG+             PG     G  G +G+PGLPG 
Sbjct: 1682 GRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGA 1741

Query: 100  PGPSAV-GKPGVPGLPGKPGERGPYGPKGDVGPAGL---------PGPRGPPGPPGIPGP 149
            PG   + G  G PG  G PG RGP G KGD GP GL         PG  GP GP G  G 
Sbjct: 1742 PGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGK 1801

Query: 150  AGI----SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG------------- 192
            AG      +PG  G+QG  G  GP G PG+ G  G PG+NG+ GE G             
Sbjct: 1802 AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGD 1861

Query: 193  YGAPGRPG------ERGLPG---PQGPTG---PSGPPGVG------------KRGENGVP 228
             GA GR G      ERG PG   PQGP G   P GPPG G             RGE G  
Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSK 1921

Query: 229  GQPGIKGDRGFPGE------------------------------------------MGPI 246
            G+ G+ G+RG  GE                                           GP 
Sbjct: 1922 GEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPK 1981

Query: 247  GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPG-APGIAGPPGPPGF----GKP 301
            G  G QGPPG+ GP  IG PG  G  G  G PG +G PG A G  GPPGP G     GKP
Sbjct: 1982 GDSGEQGPPGKEGP--IGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKP 2039

Query: 302  GLPGLKGERGPAGLPGGPGAKGEQG------------PAGLPGKPGLTGPPGNM------ 343
            G+PGL G  G  G  G PG +GE+G            P GLPG PG  GPPG        
Sbjct: 2040 GIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEP 2099

Query: 344  -----GPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDG 398
                 G QGP G+ G+ G PG  G+ GP G  G PG KG+RG PG  G+ G PG PG   
Sbjct: 2100 GPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPG--- 2156

Query: 399  PKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPG 458
                 G+ GP+G PG+ GP G PGPVG        GH G+ GP GAPG+ G  GP GP G
Sbjct: 2157 ---ERGMAGPEGKPGLQGPRGPPGPVG--------GH-GDPGPPGAPGLAGPAGPQGPSG 2204

Query: 459  IPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGP---PGPPGPR---GHSGEPGLPGPPGP 512
            +      KG+PG  GPPG      +GL GPTG    PGPPGP    G  G PGLPG  G 
Sbjct: 2205 L------KGEPGETGPPG------RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGE 2252

Query: 513  PGPPGQAVMPEGFIKAGQR--PSLSGTPLVSANQGVTGMP 550
             G PG         K G R  P + G+P +    G  G P
Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEP 2292



 Score =  388 bits (996), Expect = e-107
 Identities = 245/559 (43%), Positives = 275/559 (49%), Gaps = 96/559 (17%)

Query: 79   PPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV---GPAGLP 135
            P   P Y   G +GEPG  G  G   VG PG PGLPG+ G  GP GP G     G  G P
Sbjct: 1244 PEPCPVYCPKGQKGEPGEMGLRGQ--VGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFP 1301

Query: 136  GPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGE-MGYG 194
            G  G PG PG  G  G   PG PG +G  G PGPRG PGE+G  G  G  G  G+ +G  
Sbjct: 1302 GADGRPGSPGRAGNPG--TPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGE 1359

Query: 195  APGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPG--IKGDRGFPGEMGPIGP---- 248
             PG PG +G PGP GP GP GP  +G  G  G PG PG  +KGD+G  GE GP GP    
Sbjct: 1360 GPGLPGRKGDPGPSGPPGPRGP--LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGG 1417

Query: 249  --------------PGPQ---GPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAG 291
                          PGPQ   GPPG++G +G  + GA G PGQPG PG +G  G PG  G
Sbjct: 1418 IAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIG 1477

Query: 292  PPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGI 351
            P G  GF  PG  G  GE+G  G PG  G++G  G AG PG  G  GPPG  G QG KG 
Sbjct: 1478 PKGDRGF--PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGE 1535

Query: 352  PGSHGLP-----------GPKGETGPAGPAGYPGAKGER--------GSPGSDGKPGYPG 392
            PG  G P           G KG+ GPAGP G  G +GER        G PG  G PG  G
Sbjct: 1536 PGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595

Query: 393  KPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP---G 449
              GL G  G PG  GP G+ G  G PG PGPVGP G  G  G  G+ GP G PG+P   G
Sbjct: 1596 PIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAG 1655

Query: 450  TRGPIGPPGIPGFPGSKGDPGSPGPPG----PAGIATKGLNGPTGPPGPP---------- 495
             RG  G PG+ G  G KGD G PG  G    P     KG  G  GPPGPP          
Sbjct: 1656 ERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGA 1715

Query: 496  ------------GPRGHSGEPGLPGPP---------GPPGPPGQAVMPEGFIKAGQRPSL 534
                        GPRG  G+PGLPG P         GPPGP G   +     + G R   
Sbjct: 1716 REKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDR--- 1772

Query: 535  SGTPLVSANQGVTGMPVSA 553
             G P +    G+ G P +A
Sbjct: 1773 -GPPGLDGRSGLDGKPGAA 1790



 Score =  348 bits (892), Expect = 1e-95
 Identities = 208/445 (46%), Positives = 236/445 (53%), Gaps = 55/445 (12%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----------GSPGLQGEPGLPGPPG 101
            G+ V G  G PGPPG  G  G PG  G PG  G+          G PG  GE GL GPPG
Sbjct: 2372 GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPG 2431

Query: 102  ----PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGK 157
                P  +G PG PG  G PG  G  G KGD G  GLPGPRG  G PGI G       G+
Sbjct: 2432 REGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGE-----DGR 2485

Query: 158  PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAP--GRPGERGLPGPQGPTGPSG 215
            PGQ+GP G  GP G  GE+G  G  G  G KG+ G  A   G PG RG  G  G  GP G
Sbjct: 2486 PGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRG 2545

Query: 216  PPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQ 274
              G  G RG+N   G PG KG +G PG+ G  G PG +G  G +     G+PGAAG PG 
Sbjct: 2546 LDGDKGPRGDN---GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQ-----GQPGAAGIPGD 2597

Query: 275  PGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKP 334
            PG PG  G+   PGI G  G  GF  P   GLKGERG  G  G  G KG++G AG PG+P
Sbjct: 2598 PGSPGKDGV---PGIRGEKGDVGFMGP--RGLKGERGVKGACGLDGEKGDKGEAGPPGRP 2652

Query: 335  GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKP 394
            GL G  G M   G  G+PG  G PG +G  GP G  G+ G  G +G  G  G+ G PG  
Sbjct: 2653 GLAGHKGEM---GEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIG 2709

Query: 395  GLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPI 454
            G  GP GN G  G         PPG PG VGP G +G+ G  GE GP      PG R  +
Sbjct: 2710 GFPGPSGNDGSAG---------PPGPPGSVGPRGPEGLQGQKGERGP------PGER-VV 2753

Query: 455  GPPGIPGFPGSKGDPGSPGPPGPAG 479
            G PG+PG PG +G+ G PGP GP G
Sbjct: 2754 GAPGVPGAPGERGEQGRPGPAGPRG 2778



 Score =  293 bits (749), Expect = 5e-79
 Identities = 175/365 (47%), Positives = 200/365 (54%), Gaps = 24/365 (6%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSA-VGKPGVPGL 113
            + G  G PGPPG  GP G  G  G  G PG G PG +GE G PG  G     G+ G  GL
Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGL 2494

Query: 114  PGKPGERGPYGPKGDVGPAGLPGPRGPPGP-PGIPGPAGISVPGKPGQQGPTGAPGPRGF 172
             G PG RG  G KGDVG AGL G +G      G PGP G    G  G++GP G  G +G 
Sbjct: 2495 TGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRG--AKGDMGERGPRGLDGDKGP 2552

Query: 173  PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPG-VGKRGENGVPGQP 231
             G+ G PG  G  G+ G+   G+ G PG RGL GPQG  G +G PG  G  G++GVPG  
Sbjct: 2553 RGDNGDPGDKGSKGEPGDK--GSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIR 2610

Query: 232  GIKGDRGFPGEMGPIGPPGPQGPPGERGPEG-IGKPGAAGAPGQPGIPGTKGLPGAPGIA 290
            G KGD GF   MGP G  G +G  G  G +G  G  G AG PG+PG+ G KG  G PG+ 
Sbjct: 2611 GEKGDVGF---MGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVP 2667

Query: 291  GPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKG 350
            G  G P  GK GL G KG+RG  G PG  G +GE+G  G PG  G  GP GN G  GP  
Sbjct: 2668 GQSGAP--GKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP-- 2723

Query: 351  IPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD--GKPGYPGKPGLDGPKGNPGLPGP 408
                   PGP G  GP GP G  G KGERG PG    G PG PG PG  G +G PG  GP
Sbjct: 2724 -------PGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGP 2776

Query: 409  KGDPG 413
            +G+ G
Sbjct: 2777 RGEKG 2781



 Score = 40.0 bits (92), Expect = 0.007
 Identities = 17/33 (51%), Positives = 20/33 (60%)

Query: 52   GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG 84
            G  V G  G PG PG  G +G PGP+GP G+ G
Sbjct: 2749 GERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  426 bits (1094), Expect = e-119
 Identities = 285/667 (42%), Positives = 324/667 (48%), Gaps = 141/667 (21%)

Query: 6   PFLLLVSLNLVHGVFYAERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPP 65
           P  LLV L +V  V    + + P G +GP P       +P    S GI   G+ G PG  
Sbjct: 8   PRSLLVLLQVV--VLALAQIRGPPGERGP-PGPPGPPGVP---GSDGID--GDNGPPGKA 59

Query: 66  GPAGPRGHPG---PSGPPGKPGY-------------GSPGLQGEPGLPGPPG---PSAVG 106
           GP GP+G PG   P GP GKPG              G PG++G+PGLPGPPG   P   G
Sbjct: 60  GPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAG 119

Query: 107 KPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGP-------AGISVPGK-- 157
            PG PG  G PGE G  GPKGD GP G  GP GPPG PG PG        A    P    
Sbjct: 120 PPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCP 179

Query: 158 PGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPP 217
           PG +GP G  G +G  G++G  G PG  G+ G  G    G  GE+G+PGP GP G  G P
Sbjct: 180 PGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKG--DVGASGEQGIPGPPGPQGIRGYP 237

Query: 218 GV----GKRGENGVPGQPGIKGDRGFPGEMGPIGPPG------PQGPPGERGPEGI-GKP 266
           G+    G+ G +G  G  G  G  G PGE GP GPPG       +G PG RGP+GI G  
Sbjct: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297

Query: 267 GAAGAPG---QPGIPGTKGLPGAPGIAGPPGPPGF----GKPGLPGLKG------ERGPA 313
           GA G PG   + G PGT G+ G+ G AG PG PG     G PG PG KG      E GP 
Sbjct: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQ 357

Query: 314 GLPG---GPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAG-- 368
           GLPG    PG +GE GP G  G  G+ G  G+ G +GP G PG  G  GPKGE GP G  
Sbjct: 358 GLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIP 417

Query: 369 -PAGYPGAKGERGSPGSDGK------PGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLP 421
            P G PG KG++GSPG  G       PG  G PG  G KG  G PGPKG  GV G PG P
Sbjct: 418 GPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYP 477

Query: 422 GPVGPAGAKGMPGHNGEAGPRG------APGIPGTRG----------------------- 452
           GP G AGA G+ G+ G  GPRG       PG PG +G                       
Sbjct: 478 GPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQL 537

Query: 453 -------------------PIGPPGIPGFPGSKGDPGSPGPPGPAGIA----------TK 483
                              P GPPG PG+PG +G  G PGP G  GI            K
Sbjct: 538 AEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPK 597

Query: 484 GLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSAN 543
           G  G  G PG  G RGH G PG PG PG PG PGQA+      K G R    G+P     
Sbjct: 598 GKRGEKGDPGEVG-RGHPGMPGPPGIPGLPGRPGQAING----KDGDR----GSPGAPGE 648

Query: 544 QGVTGMP 550
            G  G+P
Sbjct: 649 AGRPGLP 655



 Score =  348 bits (892), Expect = 1e-95
 Identities = 215/491 (43%), Positives = 247/491 (50%), Gaps = 66/491 (13%)

Query: 53  IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVP 111
           +   GEQG PGPPGP G RG+PG +GP G+ G +G  G+ G  G  GPPG     + G  
Sbjct: 216 VGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPG-----EEGPR 270

Query: 112 GLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRG 171
           G PG+ GE+G  G  G  GP G+ GP+G  GPPGI G  G   PG PG +G  G  G  G
Sbjct: 271 GPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG--TPGTPGMKGSAGQAGQPG 328

Query: 172 FPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQP 231
            PG +G  GVPG  G KG  G G  G PG +GLPG  GP G  G PG   RGE G  G  
Sbjct: 329 SPGHQGLAGVPGQPGTKG--GPGDQGEPGPQGLPGFSGPPGKEGEPG--PRGEIGPQGIM 384

Query: 232 GIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI----GKPGAAGAPGQPGIPGTKGLPGAP 287
           G KGD+G  G +G  GP G QGP GE+GP GI    G PG  G  G PG  G +G  G P
Sbjct: 385 GQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDP 444

Query: 288 GIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQ 346
           G+AG PG  G  G+ G PG KG++G  G PG PG  G+ G  G+ G PG  GP G  G +
Sbjct: 445 GVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNR 504

Query: 347 GPKGIPGSHGLPGPK------------------------------------GETGPAGPA 370
           G  G PG  G+ G                                      G  GP GP 
Sbjct: 505 GVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPP 564

Query: 371 GYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG-VG-GPPGLPGPVGPAG 428
           GYPG +G  G PG  G PG  G  G  G  G  G  G KGDPG VG G PG+PGP G  G
Sbjct: 565 GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPG 624

Query: 429 AKGMPGH--NGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPP---GPAGIATK 483
             G PG   NG+ G RG+PG PG  G       PG PG  G PG   P    G +  A+ 
Sbjct: 625 LPGRPGQAINGKDGDRGSPGAPGEAGR------PGLPGPVGLPGFCEPAACLGASAYASA 678

Query: 484 GLNGPTGPPGP 494
            L  P    GP
Sbjct: 679 RLTEPGSIKGP 689



 Score = 76.6 bits (187), Expect = 7e-14
 Identities = 49/132 (37%), Positives = 56/132 (42%), Gaps = 42/132 (31%)

Query: 44  IPYTIKSKGIAVRGEQGTPGPPGPAG------PRGHPGP--------------------- 76
           +  + K + +   G  G PGPPGP G      P GHPGP                     
Sbjct: 540 VAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGK 599

Query: 77  ---SGPPGKPGYGSPGLQGEPG---LPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVG 130
               G PG+ G G PG+ G PG   LPG PG +  GK G  G PG PGE          G
Sbjct: 600 RGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGE---------AG 650

Query: 131 PAGLPGPRGPPG 142
             GLPGP G PG
Sbjct: 651 RPGLPGPVGLPG 662



 Score = 39.3 bits (90), Expect = 0.012
 Identities = 17/37 (45%), Positives = 20/37 (54%)

Query: 52  GIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP 88
           G A+ G+ G  G PG  G  G PG  GP G PG+  P
Sbjct: 630 GQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEP 666


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  423 bits (1088), Expect = e-118
 Identities = 265/593 (44%), Positives = 297/593 (50%), Gaps = 111/593 (18%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPG-PSAVGKPGVPGLPG 115
            GE+G  GPPGP G  G PGP G  G  G  SPG  G PG+ G  G P A G  G PG PG
Sbjct: 581  GERGAEGPPGPTGQAGEPGPRGLLGPRG--SPGPTGRPGVTGIDGAPGAKGNVGPPGEPG 638

Query: 116  KPGERGPYGPKGDVGPAGL---PGPRGPPGPPGIPGPAGISVP-GKPGQQGPTGAPGPRG 171
             PG++G +G +G  GP GL   PG +GPPG PGIPG  G   P G PG +GPTG  G +G
Sbjct: 639  PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQG 698

Query: 172  FPGEKGAPGVPG------------MNGQKGEMG----------------YGAPGRPGERG 203
             PG  G PG PG            + G+KGE G                 G PG PG RG
Sbjct: 699  PPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758

Query: 204  LPGPQGPTGPSG------PPG-VGKRGENGVPG------QPGIKGDRGFPGEMGPIGPPG 250
              GP+GP G +G      PPG  G++G+ GVPG      +PG KG  GFPG +GPIG  G
Sbjct: 759  EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818

Query: 251  PQGPPG------ERGPEGI----GKPGAAGAPGQ---------PGIPGTKGLPGA---PG 288
              G  G      ERGP G     G+PGA G PG          PGIPG KGLPG    PG
Sbjct: 819  KSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPG 878

Query: 289  IAGPPGPPGF----GKPGLPGLKGE---RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG 341
              GP GPPG     G+PG PG +GE   +G  G PG  G  G QG  G  G  G  GPPG
Sbjct: 879  FPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPG 938

Query: 342  NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKG 401
              GP G +G+PG  G  G KGE GP GP G  G  G RG PG  G PG PG  GL G KG
Sbjct: 939  PPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKG 998

Query: 402  NPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGP------------RGAP---- 445
                  P G  G  G PG  GP+GPAG  G+PG +G  GP            RG P    
Sbjct: 999  ------PPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG 1052

Query: 446  --GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPP---GPRGH 500
              GIPG  GP+GPPG  G  G +GD G  G PG  G  +KG  G  GPPG P   GP GH
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKG--SKGDKGDAGPPGQPGIRGPAGH 1110

Query: 501  SGEPGLPGPPGPPGPPGQAVMP-----EGFIKAGQRPSLSGTPLVSANQGVTG 548
             G PG  G  G  GPPG           GF+     P L G P     +G  G
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163



 Score =  421 bits (1083), Expect = e-118
 Identities = 255/568 (44%), Positives = 294/568 (51%), Gaps = 105/568 (18%)

Query: 49   KSKGIAVRGEQGTPGPPGPAGPRGHPG------------PSGPPGKPG----YGSPGLQG 92
            K+  +   GE+G PGPPGP G +G PG            P GP GK G     G PG +G
Sbjct: 924  KTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKG 983

Query: 93   EPGLPGPPGPSA-VGKPGVPGLPGKPGERGPYGP------------KGDVGPAGLPGPRG 139
             PG PGP G     G PG  G  G PGERGP GP            +G VGPAG  G RG
Sbjct: 984  GPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRG 1043

Query: 140  PPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGR 198
              GPPG  G  GI  PG  G  GP GA GP G  G+KG  G PG  G KG+ G  G PG+
Sbjct: 1044 ERGPPGPTGKDGI--PGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQ 1101

Query: 199  PGERGLPGPQGPTGPSG------PPGV-GKRGENGV---------------PGQPGIKGD 236
            PG RG  G  GP G  G      PPG+ G++G++GV               PG PG KG+
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGE 1161

Query: 237  RGFPGEMGPIGPPGPQGPPGERG-------PEGIGKPGAAGAPGQPGIPGTKGLPGAPGI 289
             G  G MGP G PGP+GP G  G       P G+G+PGA G  G+ G  G  G PGAPGI
Sbjct: 1162 VGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI 1221

Query: 290  AGPPG---------------PPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK 333
             GP G               PPG  G PG  G KG  GP GLPG  G  G+ G +G+ G 
Sbjct: 1222 PGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGS 1281

Query: 334  PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGS---PGSDGKPGY 390
            PG  G PG++G  GP G  G  G PGP G+ GP+G  G  G +GE+G+   PG DG PG 
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341

Query: 391  PGK------PGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGA 444
             G       PG  GP+G  G+PGP G+PG+ G PG  GP GP G  G+PG  G+ GP+G 
Sbjct: 1342 TGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGE 1401

Query: 445  PGIPGTRGPIGPPG------------IPGFPGSKGDPGSPGP------PGPAGIA-TKGL 485
             G  G  G IGPPG            + G PG KGDPG PGP      PGP G+A   G 
Sbjct: 1402 KGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQ 1461

Query: 486  NGPTGPPGPPGPRGHSGEPGLPGPPGPP 513
             G  G PG  GPRG +G  G PGPPG P
Sbjct: 1462 KGSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  419 bits (1076), Expect = e-117
 Identities = 255/596 (42%), Positives = 293/596 (49%), Gaps = 103/596 (17%)

Query: 51  KGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSP----------GLQGEPG----- 95
           KG    G  G PGP G  GP G PGP G PG PG   P          G++G PG     
Sbjct: 386 KGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMM 445

Query: 96  -------------------------------LPGPPGP-SAVGKPGVPGLPGKPGERGPY 123
                                          + GPPGP    G+PG  GLPG PG +G  
Sbjct: 446 PFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEE 505

Query: 124 GPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPG 183
           G +G  GP GL GP GPPG  G  G      PG  G +G  G  GP+G  G  G PG+PG
Sbjct: 506 GAEGPQGPRGLQGPHGPPGRVGKMGR-----PGADGARGLPGDTGPKGDRGFDGLPGLPG 560

Query: 184 MNGQKGEMGY----GAPGRPGERGLPGPQGPTGPSGPPG----VGKRGENGVPGQPGIKG 235
             GQ+G+ G+    G PG  GERG  GP GPTG +G PG    +G RG  G  G+PG+ G
Sbjct: 561 EKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTG 620

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGI----GKPGAAGAPGQPGIPGTKGLPGAPGIAG 291
             G PG  G +GPPG  GPPG++G  G     G  G  G PG+ G PG  G+PG PG  G
Sbjct: 621 IDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDG 680

Query: 292 PPGPPGF----GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGP---PGNMG 344
           P G PG     G+ G  G  G  GP G PG  G KG  G  GL G+ G  G    PG  G
Sbjct: 681 PLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKG 740

Query: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGK------PGYPGKPGLDG 398
             G KG  G  G PGP+GE GP GP G  G  GE G PGS G+      PG PG PG  G
Sbjct: 741 DVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPG 800

Query: 399 PKGNPGLPGP------KGDPGVGGPPGLPGPVGP---------AGAKGMPGHNGEAGPRG 443
           PKG+ G PGP      KG  G  G PGL G  GP          GA G PG  G+ G  G
Sbjct: 801 PKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDG 860

Query: 444 APGIPGTRGPIGPPGIPGFPGSKGDP------GSPGPPGPAG-IATKGLNGPTGPPGPPG 496
           APGIPG +G  G  G PGFPG KG P      G PG PG  G +  +G  GP GP G  G
Sbjct: 861 APGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLG 920

Query: 497 PRGHSGEP---GLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVTGM 549
           P+G +GE    G  GPPGPPGPPG+  +P    + G +  L G P     +G  G+
Sbjct: 921 PQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGEL-GPPGPLGKEGPAGL 975



 Score =  418 bits (1075), Expect = e-117
 Identities = 264/598 (44%), Positives = 296/598 (49%), Gaps = 111/598 (18%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG----YGSPGLQGEPGLPGPPGPSAV-GKPGVP 111
            GE+G  GPPG AGP G+PGP G  G  G     G  G +GE G PG  G   + G  G P
Sbjct: 692  GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751

Query: 112  GLPGKPGERGPYGPKGDVGPAGLPGPRGP------------PGPPGIPGPAG-ISVPG-- 156
            G PG  GE GP GPKG  G AG  GP G             PG PG PGP G I  PG  
Sbjct: 752  GAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL 811

Query: 157  ----------KPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY-GAPGRPGERGLP 205
                      K GQ G  G  GP G  GE+G PG  G  G KG++G  GAPG PGE+GLP
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 206  GPQGPTG---PSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPG---PQGPPGERG 259
            G QGP G   P GPPG   +G++G PG PG +G+ GF G+ GP GP G   PQG  GE G
Sbjct: 872  GLQGPPGFPGPKGPPG--HQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG 929

Query: 260  PEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGG 318
            P G  G PG  G PG+ G+PG +G  GA G  GPPGP   GK G  GL+G  GP G PG 
Sbjct: 930  PLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGP--LGKEGPAGLRGFPGPKGGPGD 987

Query: 319  PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
            PG  G +G  G PG  G  G PG  GP GP G     GLPG  G  GP GPAG  G++GE
Sbjct: 988  PGPTGLKGDKGPPGPVGANGSPGERGPLGPAG---GIGLPGQSGSEGPVGPAGKKGSRGE 1044

Query: 379  RGSPGSDGKPGYPGK------PGLDGPKGN---------PGLPGPKGDPGVGGPPGLPGP 423
            RG PG  GK G PG       PG  GP G          PG  G KGD G  GPPG PG 
Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104

Query: 424  VGPAGAKGMPGHNGEAGPRGAPGIPGTRGP---------IGPPGIPGFPG---------- 464
             GPAG  G PG +G  G RG PG+ G +G          IGPPG+ G PG          
Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGD 1164

Query: 465  --SKGDPGSPGPPGPAG-------------------IATKGLNG------PTGPPGPPGP 497
              S G  G+PGP GP G                   +  KG  G      P G PG PGP
Sbjct: 1165 VGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGP 1224

Query: 498  RGHSGEPGLPGPPGPPGPPGQAVMP-----EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            +G  GE G  GP G  GPPG+   P     +G +     P   G P      G+ G P
Sbjct: 1225 KGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP 1282



 Score =  400 bits (1027), Expect = e-111
 Identities = 234/518 (45%), Positives = 269/518 (51%), Gaps = 62/518 (11%)

Query: 57   GEQGTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAV-GKPGVPGLP 114
            G +G  G  GP GPRG  GP GPPG+ G  G PG  G  GLPG  GP    G  G+PGLP
Sbjct: 500  GLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLP 559

Query: 115  GKPGERG------------------------PYGPKGDVGPAGLPGPRGPPGPPGIPGPA 150
            G+ G+RG                        P G  G+ GP GL GPRG PGP G PG  
Sbjct: 560  GEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVT 619

Query: 151  GIS-------------VPGKPGQQGPTGA---PGPRGF---PGEKGAPGVPGMNGQKGEM 191
            GI               PG PGQQG  G+   PGP+G    PGEKG PG PG+ G  G  
Sbjct: 620  GIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSD 679

Query: 192  G-YGAPGRPGERGLPGPQGPTGPSGPPGV-------GKRGENGVPGQPGIKGDRGFPGEM 243
            G  G PG  G  G  G QGP G +GPPG        G  G  G+ G+ G KG+ GFPG  
Sbjct: 680  GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFK 739

Query: 244  GPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGL 303
            G +G  G QG PG  GP G  + G  G  GQ G  G +G PG+ G  G  G PG   PG 
Sbjct: 740  GDVGLKGDQGKPGAPGPRG--EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGL--PGY 795

Query: 304  PGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGE 363
            PG  G +G  G PG  G  GE+G +G  G+PGL G  G  G +G +G PG+ G PGPKG+
Sbjct: 796  PGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGD 855

Query: 364  TGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGP 423
             G  G  G PG KG  G  G  G PG  G PG  G  G PG PG +G+ G  G  G PGP
Sbjct: 856  VGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGP 915

Query: 424  VGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGP---PGPAGI 480
             G  G +G  G  G  G RG PG PG  G  G PG+ G  G+KG+ G PGP    GPAG+
Sbjct: 916  AGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGL 975

Query: 481  ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ 518
              +G  GP G PG PGP G  G+ G PGP G  G PG+
Sbjct: 976  --RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011



 Score =  369 bits (947), Expect = e-102
 Identities = 232/563 (41%), Positives = 265/563 (47%), Gaps = 92/563 (16%)

Query: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPG--VPGLP 114
           G+  T GP   A    +P  +     PG G  G +GEP         AV + G    G P
Sbjct: 346 GDDSTMGPDFRAAE--YPSRTQFQIFPGAGEKGAKGEP---------AVIEKGQQFEGPP 394

Query: 115 GKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI---------------------- 152
           G PG +G  GP G  GP G PG  GPPGP G+PG  GI                      
Sbjct: 395 GAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSF 454

Query: 153 ---------------------SVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEM 191
                                S+ G PG  G TG PGP G PG  G  G  G  G +G  
Sbjct: 455 KGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPR 514

Query: 192 G----YGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIG 247
           G    +G PGR G+ G PG  G  G   P   G +G+ G  G PG+ G++G  G+ G +G
Sbjct: 515 GLQGPHGPPGRVGKMGRPGADGARGL--PGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVG 572

Query: 248 PPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLK 307
            PGP G  GERG E  G PG  G  G+PG  G  G  G+PG  G PG  G    G PG K
Sbjct: 573 QPGPPGEDGERGAE--GPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGI--DGAPGAK 628

Query: 308 GERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPA 367
           G  GP G PG PG +G  G  GLPG  GL G PG  GP G  GIPG  G  GP G  G  
Sbjct: 629 GNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHE 688

Query: 368 GPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG----------VG-- 415
           GP    G KG +G PGS G PGYPG  G+ G  GN GL G KG+ G          VG  
Sbjct: 689 GPT---GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLK 745

Query: 416 ---GPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSP 472
              G PG PGP G  G +G  G  G+AG  G PG  G +G +G PG+PG+PG  G  GS 
Sbjct: 746 GDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSI 805

Query: 473 GPPGPAG-IATKGLNGPTGPP------GPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGF 525
           G PGP G I  KG +G TG P      GPPG RG  G+PG  G PGP G  GQ   P G 
Sbjct: 806 GFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAP-GI 864

Query: 526 IKAGQRPSLSGTPLVSANQGVTG 548
                 P L G P     +G  G
Sbjct: 865 PGEKGLPGLQGPPGFPGPKGPPG 887



 Score =  331 bits (849), Expect = 1e-90
 Identities = 218/534 (40%), Positives = 251/534 (47%), Gaps = 151/534 (28%)

Query: 56   RGEQGTPGP---PGPAGPRGHPGPSGPPGKPGY----------GSPGLQGEPGLPGPPGP 102
            +GE G PGP    GPAG RG PGP G PG PG           G  G  G PG  GP GP
Sbjct: 958  KGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGP 1017

Query: 103  SA-VGKPGVPGLPG------KPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG---- 151
            +  +G PG  G  G      K G RG  GP G  G  G+PGP GP GPPG  GP+G    
Sbjct: 1018 AGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGD 1077

Query: 152  ------------------ISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGY 193
                                 PG+PG +GP G PGP G  G +G  G PG+ GQKG+ G 
Sbjct: 1078 KGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGV 1137

Query: 194  -------------GAPGRPGERG------------LPGPQGPTGPSG------------- 215
                         G PG PGE+G             PGP+GP GP+G             
Sbjct: 1138 RGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQ 1197

Query: 216  PPGVGKRGENG---------VPGQPGIKGDRGFPGEMGP---IGPPGPQGPPGERGPEG- 262
            P  VG++GE G          PG PG KGD G  G+ GP    GPPG +GPPGE G +G 
Sbjct: 1198 PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGS 1257

Query: 263  ---IGKPGAAGAPGQPGIPGTKGLPGA---PGIAGPPGPPGF-GKPGLPGLKGERGPAG- 314
                G PG  G PG PG+ G  G PG    PG  G PGPPG  G+PG PG  G+RGP+G 
Sbjct: 1258 VGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH 1317

Query: 315  -----LPGGPGAKGEQGPAGLPGKPG---LTGPPGNMGPQGPKGIPGSHG------LPGP 360
                   G  GAKGE GP G PG+ G     GPPG +GP+G +GIPG  G       PG 
Sbjct: 1318 MGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQ 1377

Query: 361  KGETGPAGPAGYPGAKGERGS---------------PGSDGKPGYPGKPGLDGP---KGN 402
             G  GP GP+G PG KG+ G                PG  G+ G  G PG+ GP   KG+
Sbjct: 1378 MGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGD 1437

Query: 403  PGLPGPKGDPGVGGPPGLPGPVG------------------PAGAKGMPGHNGE 438
            PG PGP G  G  GPPG+ GP+G                  PAG  G PG   E
Sbjct: 1438 PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPGAPAE 1491


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score =  422 bits (1086), Expect = e-118
 Identities = 241/542 (44%), Positives = 276/542 (50%), Gaps = 85/542 (15%)

Query: 55  VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-------------GSPGLQGEPGLPGPPG 101
           + G++G  GPPGP GP G PG  G PGKPG              GS G +G+ G PG PG
Sbjct: 291 IDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPG 350

Query: 102 PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI--------S 153
                  G+PG PG PG  G  G  G VGP G PG RGPPGPPG PGP G          
Sbjct: 351 SRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 410

Query: 154 VPG--KPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGP 210
            P    PG+ G  G PG RG  G KG  G PG  G KGE G  G  G  G +G PG QG 
Sbjct: 411 CPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470

Query: 211 TGPSGPPG-VGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI----GK 265
            G +G  G  G++G  G+ G+PG +G  G PG+ G  GPPG  GP G+RG EG     G 
Sbjct: 471 RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 530

Query: 266 PGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-------FGKPGLPGLKGERGPAGLPGG 318
           PG  G  G PG+ G  G+PG PG  G PG PG        G PG+PG+ G +G AG  G 
Sbjct: 531 PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 590

Query: 319 PGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGE 378
            GA G+ G  G  GKPG  GPPG +GP+GP+G+PGS      +GE GP G  G PG  G 
Sbjct: 591 TGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS------RGELGPVGSPGLPGKLGS 644

Query: 379 RGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPP------------GLPGPVGP 426
            GSPG  G PG PG PG+ G +G  G PGPKG+ G  G              GLPGP G 
Sbjct: 645 LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 704

Query: 427 AGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPA-------- 478
           AG  G PG  G  G RG PG+ G RGP GP G+ G  G+ G PG  GPPG A        
Sbjct: 705 AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQ 764

Query: 479 -----------------------GIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGP 515
                                       G  GP GPPGPPG  G  G+ G+ G PG  GP
Sbjct: 765 VCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824

Query: 516 PG 517
           PG
Sbjct: 825 PG 826



 Score =  405 bits (1041), Expect = e-113
 Identities = 257/652 (39%), Positives = 295/652 (45%), Gaps = 187/652 (28%)

Query: 57  GEQGTPGPPGPAG---------------PRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPP 100
           GEQG PGPPGP G               P G PGP+G PGKPG  G PG  G  GL GP 
Sbjct: 272 GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPD 331

Query: 101 G-PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG----ISVP 155
           G P ++G  G  G PG PG RG  G        G+PGP GPPG  G+PG  G    +  P
Sbjct: 332 GSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELGRVGPVGDP 384

Query: 156 GKPGQQGPTGAPGPRGF---------------PGEKGAPGVPGMNGQKGEMG-YGAPGRP 199
           G+ G  GP G PGPRG                PG  G PG+PGM G KG  G  G PGR 
Sbjct: 385 GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ 444

Query: 200 GERGLPGPQGP---TGPSGPPGV-------------GKRGENGVPGQPGIKGDRGFPGEM 243
           G +G  G QG     G  GPPG              G++G  G+ G+PG +G  G PG+ 
Sbjct: 445 GHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ 504

Query: 244 GPIGPPGPQGPPGERGPEGI----GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-- 297
           G  GPPG  GP G+RG EG     G PG  G  G PG+ G  G+PG PG  G PG PG  
Sbjct: 505 GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 564

Query: 298 -----FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIP 352
                 G PG+PG+ G +G AG  G  GA G+ G  G  GKPG  GPPG +GP+GP+G+P
Sbjct: 565 GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 624

Query: 353 GSHGL------------------------------------------PGPKGETGPAGPA 370
           GS G                                           PGPKGE G +G  
Sbjct: 625 GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 684

Query: 371 GYPGAKGERGS---PGSDGKPGYPGKPGLDGPKGNPGLPGPKGD---------------- 411
           G  G +GE G    PG  G  G PG+PGL GP+G+ GLPG +G                 
Sbjct: 685 GEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT 744

Query: 412 --PGVGGPPG------------------------------------LPGPVGPAGAKGMP 433
             PGV GPPG                                    LPG  GP G  G P
Sbjct: 745 GLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPP 804

Query: 434 GHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPG 493
           G NG  G  G  G+PG +   GPPG  G  G KGD G  G  GP G    GL G  G PG
Sbjct: 805 GENGFPGQMGIRGLPGIK---GPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPG 861

Query: 494 PPGPR--------------GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQR 531
            PGP               G +G PG+PGPPGPPG PG        ++AGQR
Sbjct: 862 DPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913



 Score =  385 bits (989), Expect = e-107
 Identities = 232/537 (43%), Positives = 262/537 (48%), Gaps = 89/537 (16%)

Query: 91  QGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPA 150
           +G PG  GPPGP   G PGVPG+ G  G+RGP GP G       PGP G PG PG PG  
Sbjct: 268 RGPPGEQGPPGPP--GPPGVPGIDGIDGDRGPKGPPGP------PGPAGEPGKPGAPGKP 319

Query: 151 GISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGP--- 207
           G   PG  G  GP G+PG  G  G+KG PGVPG  G  G    G PG PG  GLPG    
Sbjct: 320 G--TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGR 377

Query: 208 ---------QGPTGPSGPPG----------------------------------VGKRGE 224
                    +GP GP GPPG                                   G +GE
Sbjct: 378 VGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGE 437

Query: 225 NGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGTKGL 283
            G PG+ G KG+ G  GE+G +G  GP G  G RG  GI G  G  GA G  G PG +GL
Sbjct: 438 IGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGL 497

Query: 284 PGAPGIAGPPGPPGFGKP----------GLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK 333
           PGAPG  G  GPPG   P          G+PGL G +G  GLPG  G  G  G  G  G+
Sbjct: 498 PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557

Query: 334 PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKP----- 388
           PG  GPPG+ G QG  G+PG  G  G  GE G  G  G PG  G  G PG  G P     
Sbjct: 558 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617

Query: 389 ----GYPGKPGLDGPKGNPGLPGPKGD------PGVGGPPGLPGPVGPAGAKGMPGHNGE 438
               G PG  G  GP G+PGLPG  G       PG+ GPPGLPG  G  G  G PG  GE
Sbjct: 618 RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGE 677

Query: 439 AGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPR 498
            G  G  G  G RG +G  G+PG  GS G+PG PG  GP G  ++GL G  GP GPPGPR
Sbjct: 678 QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG--SRGLPGVEGPRGPPGPR 735

Query: 499 GHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRP-----SLSGTPLVSANQGVTGMP 550
           G  GE G  G PG  GPPG+A   +   +   R      +     L   + G TG+P
Sbjct: 736 GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792



 Score =  326 bits (835), Expect = 5e-89
 Identities = 194/440 (44%), Positives = 229/440 (52%), Gaps = 53/440 (12%)

Query: 149 PAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG----------YGAPGR 198
           PA I+      ++GP G  GP G PG  G PG+ G++G +G  G           G PG 
Sbjct: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315

Query: 199 PGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE--MGPIGPPGPQGPPG 256
           PG+ G PG  G TGP G P  G  G  G  G+PG+ G RGFPG    GP GPPG  G PG
Sbjct: 316 PGKPGTPGADGLTGPDGSP--GSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPG 373

Query: 257 ERGPEG-IGKPGAAGAPGQPGIPGTKGL-------PGAPGIAGPPGPPGF-GKPGLPGLK 307
           E G  G +G PG  G PG PG PG +G        P  P  A PPG  G+ G PG+ G K
Sbjct: 374 ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN-ACPPGRSGYPGLPGMRGHK 432

Query: 308 GERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPA 367
           G +G  G PG  G KGE+G  G  G+ G  GPPG  G +G  GI G  G  G +G  G  
Sbjct: 433 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 492

Query: 368 GPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGD---PGVGGPPGLPGPV 424
           GP G PGA G++G  G  G+ G  G  G +G +G PGLPGPKGD   PGV G  G+PG  
Sbjct: 493 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552

Query: 425 GPAGAKGMPGHNGEAGPRGAPGIP---------GTRGPIGPPGIPGFPGSKGDPGSPGPP 475
           G  G  G PG  G+AG +G PG+P         G +G  G PG PG  G+ G PG  GPP
Sbjct: 553 GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 612

Query: 476 ------GPAGI-ATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKA 528
                 GP G+  ++G  GP G PG PG  G  G PGLPG PGPPG PG           
Sbjct: 613 GEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM---------K 663

Query: 529 GQRPSLSGTPLVSANQGVTG 548
           G R  + G P     QG +G
Sbjct: 664 GDR-GVVGEPGPKGEQGASG 682



 Score =  192 bits (489), Expect = 7e-49
 Identities = 131/315 (41%), Positives = 147/315 (46%), Gaps = 75/315 (23%)

Query: 57  GEQGTPGPPGPAGPRGHPG------PSGPPGKPG-YGSPGLQGEPGLPGPPG-------P 102
           G+QG PG  GP GP+G PG      P G PG PG  GS G  G PGLPGPPG        
Sbjct: 607 GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 666

Query: 103 SAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGP---PGPPGIPGPAGISVPGKPG 159
             VG+PG  G  G  GE G  G +G++G  GLPGP+G    PG PG+ GP G    G PG
Sbjct: 667 GVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR--GLPG 724

Query: 160 QQGPTGAPGPRGFPGEKGAPGVPGMNGQKG---------------------EMGY----- 193
            +GP G PGPRG  GE+GA G+PG+ G  G                     EM       
Sbjct: 725 VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784

Query: 194 --GAPGRPGERGLPGPQGPTGPSGPPG-VGKRGENGVPGQPGI------KGDRGFPGEMG 244
             GA G PG  G PGP GP G +G PG +G RG  G+ G PG       KGD G  GE G
Sbjct: 785 DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG 844

Query: 245 P-----------IGPPGPQGPP--------GERGPEGIGKPGAAGAPGQPGIPGTKGLPG 285
           P           IG PG  GP         GERGP G+   G  G PG PG PG  G   
Sbjct: 845 PPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVA--GIPGVPGPPGPPGLPGFCE 902

Query: 286 APGIAGPPGPPGFGK 300
                   G   F K
Sbjct: 903 PASCTMQAGQRAFNK 917



 Score =  149 bits (375), Expect = 1e-35
 Identities = 100/239 (41%), Positives = 109/239 (45%), Gaps = 52/239 (21%)

Query: 56  RGEQGTPGPPGPAGPRGH------PGPSGPPGKPGY-------GSPGLQGEPGLPGPPGP 102
           +GEQG  G  G AG RG       PGP G  G PG        GS GL G  G  GPPGP
Sbjct: 675 KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734

Query: 103 SAV----GKPGVPGLPGKPG---------------------ERGPYGPKGDVGPAGLPGP 137
             V    G  G+PG+ G PG                     E      + D G  GLPG 
Sbjct: 735 RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794

Query: 138 RGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPG 197
            GPPGPPG PG  G      PGQ G  G PG +G PG  G  G  G  G+KGE   G PG
Sbjct: 795 PGPPGPPGPPGENGF-----PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER--GPPG 847

Query: 198 RPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPG 256
           R G  GLPG  G  G  GP   G+ G +G  G PG+ G  G P      GPPGP G PG
Sbjct: 848 R-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP------GPPGPPGLPG 899



 Score =  103 bits (258), Expect = 4e-22
 Identities = 62/137 (45%), Positives = 75/137 (54%), Gaps = 17/137 (12%)

Query: 47  TIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVG 106
           ++K       G  G PGPPGP GP   PG +G PG+      G++G PG+ GPPG  A+G
Sbjct: 780 SLKRPDSGATGLPGRPGPPGPPGP---PGENGFPGQ-----MGIRGLPGIKGPPG--ALG 829

Query: 107 KPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGA 166
             G  G  G+ GERGP G     GP GLPG  G PG    PGPA     G+ G++GP G 
Sbjct: 830 LRGPKGDLGEKGERGPPGR----GPNGLPGAIGLPGD---PGPASYGRNGRDGERGPPGV 882

Query: 167 PGPRGFPGEKGAPGVPG 183
            G  G PG  G PG+PG
Sbjct: 883 AGIPGVPGPPGPPGLPG 899



 Score =  102 bits (255), Expect = 9e-22
 Identities = 56/120 (46%), Positives = 62/120 (51%), Gaps = 19/120 (15%)

Query: 420 LPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT---------RGPIGPPGIPGFPGSKGDPG 470
           LP  + P+      G  GE GP G PG PG          RGP GPPG PG  G  G PG
Sbjct: 255 LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314

Query: 471 SPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGP--------PGPPGPPGQAVMP 522
           +PG PG  G    GL GP G PG  G +G  GEPG+PG         PGPPGPPG A +P
Sbjct: 315 APGKPGTPG--ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLP 372


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  422 bits (1086), Expect = e-118
 Identities = 268/632 (42%), Positives = 300/632 (47%), Gaps = 149/632 (23%)

Query: 60   GTPGPPGPAGPRGHPGPSGPPGKPG-YGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPG 118
            G PGPPGP G +G PG  G  G PG  G PGL G+PGLPG  G  AV  PG PG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 119  ERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGI-SVPGKPGQQGPTGA--PGPRG---- 171
            ERG  G  G++G  GLPG  G PG  G+ GP G    PG PG+QGP G    GPRG    
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 172  -------------------------------FPGEKGAPGVPGMNGQKGEMGY-GAPGRP 199
                                           FPGE G+PG+PG  G+ G +G  G PG P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 200  GERGLPGPQG---------PTGPSGPPG-VGKRGENGVPGQPGIKGDRGFPG---EMGPI 246
            G  G PG  G           GP GPPG  G  G+ G PG PG+KG RG PG   E G  
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 247  GPPGPQ------GPPGERGPEGI-GKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPG-- 297
            G PGP       G  GE G +G  G PG  G  G PG+PG KGL G PG AGPPGP G  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 298  --FGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPG-------------- 341
               G PG PGL+G  G  G  G PG+KG++G  G PG+ G  G PG              
Sbjct: 1000 GSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYS 1059

Query: 342  ---NMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDG 398
                 GP GP G PG  G  G KGE G  GP G+ G  G  G+PGS G PG PGKPG  G
Sbjct: 1060 EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHG 1119

Query: 399  PKGNPGLPGPKGDPGVGGPPGLPG------PVG-------------------------PA 427
              G  G+ G  G PG+ GPPGLPG      P+G                         P 
Sbjct: 1120 DLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPP 1179

Query: 428  GAKGMPGHNGEAGPRGAPGIP------------GTRGPI------GPPGIPGF------- 462
            G +G PG  G  G RGAPG P            G RGP       GPPG+PG        
Sbjct: 1180 GPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239

Query: 463  ----PGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQ 518
                PGS+G PG+PGPPGP G    G+ G  G  G PGP+G  G  G  GPPG  G PG 
Sbjct: 1240 NRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGT 1299

Query: 519  AVMPEGFIKAGQR--PSLSGTPLVSANQGVTG 548
              +P      G R  P   G P V   +G  G
Sbjct: 1300 PGLP------GPRGDPGFQGFPGVKGEKGNPG 1325



 Score =  416 bits (1069), Expect = e-116
 Identities = 262/606 (43%), Positives = 296/606 (48%), Gaps = 98/606 (16%)

Query: 30   GIKGPLPNTKTQFFIPYTIKSKGI-------AVRGEQGTPGPPGPAGPRGHPGPSGPPGK 82
            G++G  P  K    IP T   KG+       A+ GE+G  GPPG  G  G PGP+GP G 
Sbjct: 557  GLRGQ-PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615

Query: 83   PGYG---SPGLQGEPGLPGPPGPS-----------AVGKPGVPGLPGKPGERGPYGPKGD 128
            PGYG    PGLQG  G+PG PGP            +   PG PG PG PG  GP GP G 
Sbjct: 616  PGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGI 675

Query: 129  VGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPTGAPGPRGF------PGEKGAPGVP 182
             G  G  G  G PGP G PG  GI  PG PG +G  G PG +G        GE G PG P
Sbjct: 676  PGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735

Query: 183  GMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE 242
            G+ G KGE     PG PG  G PG +G +G        + GE G+PG PG+ G  G  G 
Sbjct: 736  GLPGAKGEPAVAMPGGPGTPGFPGERGNSG--------EHGEIGLPGLPGLPGTPGNEGL 787

Query: 243  MGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPG 302
             GP G PG  GPPGE+GP G    G  GA G PG+ G KG  G  G  GP G PG   PG
Sbjct: 788  DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI--PG 845

Query: 303  LP--GLKGERGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGP 360
            L   G  GE G  G+PG  G  G  G  G PG PG+ GPPG  G  G  G PG+ G PGP
Sbjct: 846  LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905

Query: 361  KGE---TGPAGPAGYPGAKGERGSPGSDGKPGYPGKPG------LDGPKGNPGL------ 405
             G     G  G  G PG KG+RG+PG+ G+ G  G PG      + G KG PGL      
Sbjct: 906  PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965

Query: 406  PGPKGDPGVGGPP------GLPGPVGPAGAK---GMPGHNGEAGPRGAP----------- 445
            PG KG+ GV G P      GLPGP GP G +   G  G+ GE G RG P           
Sbjct: 966  PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGS 1025

Query: 446  -------GIPGTRGPIGPPGIPGFPGSKGDPG-----SPGPPGPAG-------IATKGLN 486
                   G PG  G  G PGI G  G KG+PG      PGPPGP G       +  KG  
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 487  GPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGV 546
            G  GPPG  GP G  G PG PG PG PG PG    P G +       L G P +    G+
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPG----PHGDLGFKGIKGLLGPPGIRGPPGL 1141

Query: 547  TGMPVS 552
             G P S
Sbjct: 1142 PGFPGS 1147



 Score =  413 bits (1061), Expect = e-115
 Identities = 251/546 (45%), Positives = 286/546 (52%), Gaps = 59/546 (10%)

Query: 53   IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY----GSPGLQGEPGLPGPPGPSAV--- 105
            I + G  G  GPPGP G  G PG  G PG PG     G+PG +GE G  G PGPS +   
Sbjct: 891  IGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHV 950

Query: 106  ----GKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQ 161
                G+PG+ G  G PGE+G    +G  G  GL G +G PGP G PGP G       G  
Sbjct: 951  IGDKGEPGLKGFAGNPGEKGN---RGVPGMPGLKGLKGLPGPAGPPGPRG-----DLGST 1002

Query: 162  GPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGK 221
            G  G PG RG PG  G  G+PG  G++G +G+  PGR G  GLPG  G  G  G PG   
Sbjct: 1003 GNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGF--PGRAGRPGLPGIHGLQGDKGEPGYS- 1059

Query: 222  RGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI-GKPGAAGAPGQPGIPGT 280
              E   PG PG  GD G PG+MG  G  G  GPPG  GP G  G PG+ G+PG PG PG 
Sbjct: 1060 --EGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117

Query: 281  ---------KGLPGAPGIAGPPGPPGF-GKPGLPGLKGERGPAGLPGGPGAKGEQGPAGL 330
                     KGL G PGI GPPG PGF G PG  G++G++G  G+PG  G KGE G    
Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRA 1177

Query: 331  PGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGK--P 388
            P  PG  G PG  G +G +G PG  GLPG KG  G AGP G  G +G  G PG  G   P
Sbjct: 1178 P--PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIP 1235

Query: 389  GYPGKPGLDGPKGNPGLPGPKGDPG--VGGPPGLPGPVGPAGAKGMPGHNGEAGPRG--- 443
            G  G  G  G +G+PG PGP G PG  V G  G  G +G  G KG PG  G+ GP G   
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLG 1295

Query: 444  APGIPGTRGPIGPPGIPGFPGSKGDPGSPG------PPGPAGI-ATKGLNGPTGP----- 491
            APG PG  GP G PG  GFPG KG+ G+PG      PPGP G     G+ G  G      
Sbjct: 1296 APGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIIS 1355

Query: 492  -PGPPGPRGHSGEPGLPGPPGPPGPPGQ--AVMPEGFIKAGQRPSLSGTPLVSANQGVTG 548
             PG PGP G  GEPG+ G PGPPGPPG      P G      +P   G      N+G  G
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415

Query: 549  MPVSAF 554
             P S F
Sbjct: 1416 EPESLF 1421



 Score =  402 bits (1032), Expect = e-112
 Identities = 255/575 (44%), Positives = 286/575 (49%), Gaps = 91/575 (15%)

Query: 55   VRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPGLQGEPGLPGPPGPSA-----VGKP 108
            + G +G PG  G AG +G PG  G  G PG+ G PG QG+PGL G  G +      VG P
Sbjct: 494  LHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553

Query: 109  GVPGLPGKPGERGPYGPKGDVGPAGLPGPRGP---------PGPPGIPGPAGISVPGKPG 159
            G PGL G+PG +G  G  G  G  GLPGP+G           GPPG PG      PG PG
Sbjct: 554  GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGS-----PGSPG 608

Query: 160  QQGPTGAP--GPRGFPGEKGAPGVPGMNGQKGEMG-----------YGAPGRPGERGLPG 206
              GP G P  GP+G PG +G  GVPG  G  GE G            G PG PG  G PG
Sbjct: 609  PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 207  PQGP------TGPSGPPGV-GKRGENGV-----PGQPGIKGDRGFPGEMGPIGPPGPQGP 254
            PQGP       G  G PG+ G  GE G+     PG PG KGD+GFPG  G +G PG  G 
Sbjct: 669  PQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGE 728

Query: 255  PGERGPEGI----GKPGAA--GAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKG 308
            PG  G  G+    G+P  A  G PG PG PG +G  G  G  G PG PG   PG PG +G
Sbjct: 729  PGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL--PGTPGNEG 786

Query: 309  ERGPAGLPGGPGAKGEQGP-----------AGLPGKPGLTGPPGNMGPQGPKGIP----- 352
              GP G PG PG  GEQGP            GLPG  GL G  G  G  GPKG P     
Sbjct: 787  LDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGL 846

Query: 353  ---------GSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD---GKPGYPGKPGLDGPK 400
                     GS G+PG +GE GP G  GYPG  G  G PG D   G  G+PG  G  GP 
Sbjct: 847  DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906

Query: 401  GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP 460
            GNPG PG +G PG+   PG+ G  G  GAKG  G  G  GP     + G +G  G  G  
Sbjct: 907  GNPGTPGQRGSPGI---PGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFA 963

Query: 461  GFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAV 520
            G PG KG+ G PG PG  G+  KGL GP GPPGP G  G +G PG PG  G PG  G   
Sbjct: 964  GNPGEKGNRGVPGMPGLKGL--KGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMG 1021

Query: 521  MPEGFIKAGQ-----RPSLSGTPLVSANQGVTGMP 550
            MP    K G      R    G P +   QG  G P
Sbjct: 1022 MPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEP 1056



 Score =  387 bits (994), Expect = e-107
 Identities = 264/628 (42%), Positives = 302/628 (48%), Gaps = 121/628 (19%)

Query: 28  PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPG-YG 86
           P   KG +   K Q F      +KG   +GE+G PGPPG  G +G  GP G PG  G  G
Sbjct: 25  PAASKGCVCKDKGQCFCD---GAKG--EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKG 79

Query: 87  SPGLQGEPGLPGPPGPSAV-GKPGVPGLPGKPGERGPYGP------KGDVGPAGLPGPRG 139
            PGL G  G  G  G S + G  G PGLPG PG  GPYG        G  G  G PG  G
Sbjct: 80  FPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPG 139

Query: 140 PPGPPGIPGPAGISV------------------PGKPGQQGPTGAPGPRGFPGEKGAPGV 181
             G PGIPG AG+                    PG PG  GP G PGP GFPG  G PG 
Sbjct: 140 TLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGP 199

Query: 182 PGMNGQKGEMGYGAP-GRPGER-----GLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKG 235
           PG  G  G MG   P G  GER     G  G +G TGP GPPG       G   +  +KG
Sbjct: 200 PGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG 259

Query: 236 DRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP 295
           ++G  G MG  GPPGP G PGE      G PG  G  G+PG  G  G PG+ G+ G  G 
Sbjct: 260 EKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGF 319

Query: 296 PG-FGKPGLPGLKGERGPAGL------------------PGGPGAKGEQGPAGLPGKPGL 336
           PG  G+ G+ G KG+ GP G                   PG PG +G +GP G  G PG+
Sbjct: 320 PGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGV 379

Query: 337 TGPPGNMGPQGPKGIPGSHGLPGPKGETGPAG--PAGYPGAKGERGSPGSDGKPGYPGKP 394
            G PG+  P G +G PG  GL G KGE G  G    G PG+ G  GSPG  G PG PG P
Sbjct: 380 PGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPP 438

Query: 395 -------------GLDGPKGNPGLP---GPKGDPG--------VGGPPGLPGPVGPAGAK 430
                        GL G  G+PG+P   GPKG+PG        + GPPGLPG  G  G K
Sbjct: 439 GDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVK 498

Query: 431 GMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPG-------PPGPAGI--- 480
           G+PG  G AG +G+PG PG     G PG PGFPG++GDPG  G       P G  G+   
Sbjct: 499 GIPGRQGAAGLKGSPGSPGN---TGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555

Query: 481 -------ATKGLNGPTGPPGP---PGPRGH---SGEPGLPGPPGPPGPPGQ-----AVMP 522
                    KGL+G  G PG    PGP+G    SGE G  GPPG PG PG         P
Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615

Query: 523 EGFIKAGQRPSLSGTPLVSANQGVTGMP 550
            G+   G+ P L GT      QGV G P
Sbjct: 616 PGYGPQGE-PGLQGT------QGVPGAP 636



 Score =  152 bits (385), Expect = 8e-37
 Identities = 96/219 (43%), Positives = 105/219 (47%), Gaps = 23/219 (10%)

Query: 28   PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGS 87
            PTGI+G           P      G  + G+ G  GPPG  G  G PGP GPPG    G 
Sbjct: 1217 PTGIEG----------FPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGI 1266

Query: 88   PGLQGEPGLPGPPG-PSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGI 146
             G +G  G PGP G P   G  G PG  G PG  G  GP+GD G  G PG +G  G PG 
Sbjct: 1267 KGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGF 1326

Query: 147  PGPAGISVPGKPGQQGPTGAPGPRGFPGEK---GAPGVPGMNGQKGEMGYGAPGRPGERG 203
             G       G PG  GP G PG RG PG       PG PG  G  GE   G  G PG  G
Sbjct: 1327 LGSI-----GPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP--GMQGEPGPPG 1379

Query: 204  LPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGE 242
             PG  GP GP G P  GK G+ G PG  G KG++G  GE
Sbjct: 1380 PPGNLGPCGPRGKP--GKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  150 bits (379), Expect = 4e-36
 Identities = 97/235 (41%), Positives = 115/235 (48%), Gaps = 18/235 (7%)

Query: 341 GNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK 400
           G  G +G KG PG  G PG KG TGP             G PG  G  G+PG PGL G K
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGP------------EGLPGPQGPKGFPGLPGLTGSK 90

Query: 401 GNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIP 460
           G  G+ G  G  G  G PG PG  GP G  G+PG +G  G +G PG+PGT   +G PGIP
Sbjct: 91  GVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGT---LGYPGIP 147

Query: 461 GFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLPGPPGPPGPPG--Q 518
           G  G KG  G+P       +  KG  G  G PGP G  G  G PG  GPPGPPG  G   
Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 519 AVMPEGFIKAGQRPSLSGTPLVSANQGVTGMPVSAFTVILSKAYPAIGTPIPFDK 573
           A+ P G  K      + G       +G+TG P    TVI++   P   T +  +K
Sbjct: 208 AMGPRG-PKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEK 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.146    0.479 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 55,505,313
Number of Sequences: 37866
Number of extensions: 5589594
Number of successful extensions: 271117
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 796
Number of HSP's successfully gapped in prelim test: 2047
Number of HSP's that attempted gapping in prelim test: 20780
Number of HSP's gapped (non-prelim): 31173
length of query: 680
length of database: 18,247,518
effective HSP length: 109
effective length of query: 571
effective length of database: 14,120,124
effective search space: 8062590804
effective search space used: 8062590804
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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