Guide to the Human Genome
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Search of human proteins with 166235178

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]    655   0.0  
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]    540   e-154
gi|13994151 PDZ and LIM domain 1 [Homo sapiens]                       342   3e-94
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]             263   2e-70
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]             157   9e-39
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]            143   2e-34
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]             137   2e-32
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]            122   3e-28
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            122   3e-28
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]             120   2e-27
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]             119   5e-27
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]            106   2e-23
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             106   2e-23
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]              98   8e-21
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]              95   7e-20
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]             90   3e-18
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]              87   1e-17
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]              87   1e-17
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]             87   1e-17
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              65   6e-11
gi|193083191 synaptopodin 2 isoform c [Homo sapiens]                   59   6e-09
gi|193083185 synaptopodin 2 isoform b [Homo sapiens]                   59   6e-09
gi|193083183 synaptopodin 2 isoform a [Homo sapiens]                   59   6e-09
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               56   4e-08
gi|194272207 actin binding LIM protein family, member 2 isoform ...    53   4e-07
gi|153792514 actin binding LIM protein family, member 2 isoform ...    53   4e-07
gi|194272204 actin binding LIM protein family, member 2 isoform ...    53   4e-07
gi|194272202 actin binding LIM protein family, member 2 isoform ...    53   4e-07
gi|194272200 actin binding LIM protein family, member 2 isoform ...    53   4e-07
gi|194272198 actin binding LIM protein family, member 2 isoform ...    53   4e-07

>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
          Length = 316

 Score =  655 bits (1689), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
Sbjct: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120
           THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN
Sbjct: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120

Query: 121 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP 180
           RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP
Sbjct: 121 RRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQNEPTASVP 180

Query: 181 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA 240
           PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA
Sbjct: 181 PESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGA 240

Query: 241 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR 300
           QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR
Sbjct: 241 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARAR 300

Query: 301 TKPPEGYDTVTLYPKA 316
           TKPPEGYDTVTLYPKA
Sbjct: 301 TKPPEGYDTVTLYPKA 316


>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
          Length = 364

 Score =  540 bits (1391), Expect = e-154
 Identities = 275/364 (75%), Positives = 288/364 (79%), Gaps = 48/364 (13%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
Sbjct: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120
           THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQ+       HN
Sbjct: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120

Query: 121 RRAQPFVA------------------------------------------AANIDDKRQ- 137
            R +PFV                                           A NI  + + 
Sbjct: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180

Query: 138 ----VVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSP-QNEPTASVPPESDVYRMLHDN 192
               +V A +N+P+ LYS  NI + L GQ+   +  +P  +EPTASVPPESDVYRMLHDN
Sbjct: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN 240

Query: 193 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 252
           RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG
Sbjct: 241 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 300

Query: 253 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 312
           IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL
Sbjct: 301 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 360

Query: 313 YPKA 316
           YPKA
Sbjct: 361 YPKA 364


>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
          Length = 329

 Score =  342 bits (877), Expect = 3e-94
 Identities = 170/326 (52%), Positives = 218/326 (66%), Gaps = 13/326 (3%)

Query: 3   QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTH 62
           Q + L GP PWGFRL GG DF QPL I+R+TPGSKAA ANLC GDVI AIDG  T +MTH
Sbjct: 4   QQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTH 63

Query: 63  ADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRR 122
            +AQ+RIK     L L + R E  +WSP V+E+GK HP+K+NL SEPQE   IG+AHNR 
Sbjct: 64  LEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRS 123

Query: 123 AQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQD---------ALHGQLRGLIPSSPQN 173
           A PF A+       +V++  YN+P GLYS+ NI +         A  G      P     
Sbjct: 124 AMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQ 183

Query: 174 EPTASV-PPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTRSVRAP 229
            P++ V   ES+VY+ML + +     P+QS SF VLQ +++    G  ++P+G RSV+AP
Sbjct: 184 PPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAP 243

Query: 230 VTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEG 289
           VTKV    G AQ++P+CDKCG+GIVG  VK RD++RHPEC+VC DC  NLKQKG+FF+E 
Sbjct: 244 VTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVED 303

Query: 290 ELYCETHARARTKPPEGYDTVTLYPK 315
           ++YCE HAR R  PPEGY+ VT++PK
Sbjct: 304 QIYCEKHARERVTPPEGYEVVTVFPK 329


>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
          Length = 330

 Score =  263 bits (672), Expect = 2e-70
 Identities = 146/332 (43%), Positives = 196/332 (59%), Gaps = 23/332 (6%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MP +V L GP+PWGFRL GG DF+ PL I+R+  GSKAA A LCPGD+I AI+G  TE M
Sbjct: 1   MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120
           TH +AQ+RIK     L L + R E   W P   +D KA   +I+++ E Q+  P  +   
Sbjct: 61  THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTSR-- 117

Query: 121 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGLIPSSPQN-EPTA 177
              +P       +D R  + + Y  P    +    + +  L  Q+  L  S P + +P  
Sbjct: 118 ---RPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 174

Query: 178 SVPPE--------SDVYRMLHDNRNEPT--QPRQSGSFRVLQGMVDDGSDDR---PAGTR 224
            +P          S+VYRML +   EP   +P+QSGSFR LQGM++ G       P G R
Sbjct: 175 GLPRSRDCRVDLGSEVYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPR 233

Query: 225 SVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGY 284
           +++   +K+     G Q +P C +CG GIVG +VKARDK  HPECF+C+DC LNLKQ+GY
Sbjct: 234 NLKPTASKLGAPLSGLQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGY 293

Query: 285 FFIEGELYCETHARARTKPPEGYDTVTLYPKA 316
           FF++  LYCE+HA+AR KPPEGYD V +YP A
Sbjct: 294 FFLDERLYCESHAKARVKPPEGYDVVAVYPNA 325


>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
          Length = 352

 Score =  157 bits (398), Expect = 9e-39
 Identities = 109/347 (31%), Positives = 167/347 (48%), Gaps = 45/347 (12%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDR----------GETHLWSPQVSEDGKAHPFKINLESEPQ 110
            HA+AQ +I+ +   L L++DR          G++ L        G    +  +  S   
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120

Query: 111 EFKPIGTAHNRRAQPF---------VAAANIDDKRQVVSASYNSP----IGLYSTSNIQD 157
            +    +   R   PF            A I    Q ++ S   P    +        + 
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180

Query: 158 ALHGQLRG----LIPSSPQNEPTASVPP------------ESDVYRMLHDNRNEPTQPRQ 201
           A  G+       ++P SP   P +S P             +S+V++ML +NR     PRQ
Sbjct: 181 AGLGRAGDSAVLVLPPSPG--PRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQ 238

Query: 202 SGSFRVLQGMVD-DGSDDRPAGTRSVRAPVTKVHGGSGGAQ--RMPLCDKCGSGIVGAVV 258
           S SFR+LQ  ++ +     PA   S  +P + +      A   ++  C+KC + I    V
Sbjct: 239 SSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAV 298

Query: 259 KARD-KYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPP 304
           + ++ +YRHP C+ CADC LNLK +G+F++  ELYCE HAR R   P
Sbjct: 299 RIQEGRYRHPGCYTCADCGLNLKMRGHFWVGDELYCEKHARQRYSAP 345


>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
          Length = 246

 Score =  143 bits (360), Expect = 2e-34
 Identities = 90/243 (37%), Positives = 126/243 (51%), Gaps = 20/243 (8%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MP +V L GP+PWGFRL GG DF+ PL I+R+  GSKAA A LCPGD+I AI+G  TE M
Sbjct: 1   MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120
           TH +AQ+RIK     L L + R E   W P   +D KA   +I+++ E Q+  P      
Sbjct: 61  THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSP-----T 114

Query: 121 RRAQPFVAAANIDDKRQVVSASYNSP--IGLYSTSNIQDALHGQLRGL-IPSSPQNEPTA 177
              +P       +D R  + + Y  P    +    + +  L  Q+  L +   P  +P  
Sbjct: 115 TSRRPSGTGTGPEDGRPSLGSPYGQPPRFPVPHNGSSEATLPAQMSTLHVSPPPSADPAR 174

Query: 178 SVPPE--------SDVYRMLHDNRNEP--TQPRQSGSFRVLQGMVDDGSDDRPAGTRSVR 227
            +P          S+VYRML +   EP   +P+QSGSFR LQGM++ G    P+      
Sbjct: 175 GLPRSRDCRVDLGSEVYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTS 233

Query: 228 APV 230
           + +
Sbjct: 234 STI 236


>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
          Length = 366

 Score =  137 bits (344), Expect = 2e-32
 Identities = 97/327 (29%), Positives = 154/327 (47%), Gaps = 41/327 (12%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDR----------GETHLWSPQVSEDGKAHPFKINLESEPQ 110
            HA+AQ +I+ +   L L++DR          G++ L        G    +  +  S   
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120

Query: 111 EFKPIGTAHNRRAQPF---------VAAANIDDKRQVVSASYNSP----IGLYSTSNIQD 157
            +    +   R   PF            A I    Q ++ S   P    +        + 
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180

Query: 158 ALHGQL--RGLIPSSPQNEPTASVP------------PESDVYRMLHDNRNEPTQPRQSG 203
           A  G+     ++   P   P +S P             +S+V++ML +NR     PRQS 
Sbjct: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240

Query: 204 SFRVLQGMVD-DGSDDRPAGTRSVRAPVTKVHGGSGGA--QRMPLCDKCGSGIVGAVVKA 260
           SFR+LQ  ++ +     PA   S  +P + +      A   ++  C+KC + I    V+ 
Sbjct: 241 SFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASRALATPPKLHTCEKCSTSIANQAVRI 300

Query: 261 RD-KYRHPECFVCADCNLNLKQKGYFF 286
           ++ +YRHP C+ CADC LNLK +G+F+
Sbjct: 301 QEGRYRHPGCYTCADCGLNLKMRGHFW 327


>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
          Length = 283

 Score =  122 bits (307), Expect = 3e-28
 Identities = 79/234 (33%), Positives = 120/234 (51%), Gaps = 23/234 (9%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHL----WSPQVSEDGKAHPFKINLESEP------Q 110
           TH +AQ++IK+A++ L L + + +  +     +P V       P +  + + P      +
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120

Query: 111 EFKPIGTAHNR-RAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPS 169
            F P     +       +    +  K  ++ A YN+PI +YS   I DA+ GQ +     
Sbjct: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180

Query: 170 SPQNEP--TASVPPESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
              + P    +V   S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  122 bits (307), Expect = 3e-28
 Identities = 79/234 (33%), Positives = 120/234 (51%), Gaps = 23/234 (9%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHL----WSPQVSEDGKAHPFKINLESEP------Q 110
           TH +AQ++IK+A++ L L + + +  +     +P V       P +  + + P      +
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120

Query: 111 EFKPIGTAHNR-RAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPS 169
            F P     +       +    +  K  ++ A YN+PI +YS   I DA+ GQ +     
Sbjct: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180

Query: 170 SPQNEP--TASVPPESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
              + P    +V   S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 21/51 (41%), Positives = 27/51 (52%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           PLC KC + I+G V+ A  +  H  CFVCA C        +   +GE YCE
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 240 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           + R PLC  C + I G  + A  +  HPE F CA C  +L    +   +  +YCE
Sbjct: 435 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 11/32 (34%), Positives = 20/32 (62%)

Query: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
           H  CF+CA C++NL+ + ++  +    C+ HA
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score =  120 bits (301), Expect = 2e-27
 Identities = 94/324 (29%), Positives = 142/324 (43%), Gaps = 35/324 (10%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFK------INLESEPQEF---KPI 115
           AQ++I+A   +L L + R +     PQ +    A P +      ++L    + F    P 
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFGAPPPA 125

Query: 116 GTAHNRRAQPFVAAANIDDKRQVV--------------SASYNSPIGLYSTSNIQDALHG 161
            +A  +  QP         K++++              S S+     L  T  +QD    
Sbjct: 126 DSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEE 185

Query: 162 QLR--GLIPSSPQNEPTASVPPESDVYRMLHDNRNEP---TQPRQSGSFRVLQGMVDDGS 216
            L+    +P +    P +S P E           + P     P  +  +   +       
Sbjct: 186 HLKKSSQVPRTEAPAPASSTPQEPWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTR 245

Query: 217 DDRPA-------GTRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPEC 269
             +PA        T  V+A    V GG     + P+C +C   I G  + A     HPE 
Sbjct: 246 HSQPATPTPLQSRTSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEE 305

Query: 270 FVCADCNLNLKQKGYFFIEGELYC 293
           FVC+ C   L++ G+F  +G ++C
Sbjct: 306 FVCSQCGKVLEEGGFFEEKGAIFC 329



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           P C KC   I G ++ A     H  CF CA C   ++ + ++  EG  YCE
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 389



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
           H  CFVCA C +NL+ K ++  +    C++HA
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 453


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score =  119 bits (297), Expect = 5e-27
 Identities = 89/301 (29%), Positives = 134/301 (44%), Gaps = 23/301 (7%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQ 124
           AQ++I+A   +L L + R +     PQ  +     P +  L  +  + + +    + R +
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKVQTPDKQPLR-PLVPDASKQRLMENTEDWRPR 124

Query: 125 PFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLR--GLIPSSPQNEPTASVPPE 182
           P              S S+     L  T  +QD     L+    +P +    P +S P E
Sbjct: 125 PGTGQ----------SRSFRILAHLTGTEFMQDPDEEHLKKSSQVPRTEAPAPASSTPQE 174

Query: 183 SDVYRMLHDNRNEP---TQPRQSGSFRVLQGMVDDGSDDRPA-------GTRSVRAPVTK 232
                      + P     P  +  +   +         +PA        T  V+A    
Sbjct: 175 PWPGPTAPSPTSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQSRTSIVQAAAGG 234

Query: 233 VHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELY 292
           V GG     + P+C +C   I G  + A     HPE FVC+ C   L++ G+F  +G ++
Sbjct: 235 VPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIF 294

Query: 293 C 293
           C
Sbjct: 295 C 295



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           P C KC   I G ++ A     H  CF CA C   ++ + ++  EG  YCE
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 355



 Score = 34.7 bits (78), Expect = 0.11
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
           H  CFVCA C +NL+ K ++  +    C++HA
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 419


>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
          Length = 330

 Score =  106 bits (265), Expect = 2e-23
 Identities = 84/281 (29%), Positives = 125/281 (44%), Gaps = 70/281 (24%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGET------------------------------HLWSP 90
           TH +AQ++IK+A++ L L + + +                                L +P
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120

Query: 91  QVSEDGKAHPFKINLE----------SEPQEFKPIGTAHN---------RRAQPFVAAAN 131
             S + +A P                S P  F  +  A +          +  P  A   
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180

Query: 132 IDDKRQVVSA---SYNSPIGLYSTSNIQD-------ALHGQLRGL-IPSSPQNEPTASVP 180
           +  K    S+    YN+PIGLYS   +++       +L G+  G+ +P         +V 
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240

Query: 181 PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
             S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  106 bits (265), Expect = 2e-23
 Identities = 84/281 (29%), Positives = 125/281 (44%), Gaps = 70/281 (24%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGET------------------------------HLWSP 90
           TH +AQ++IK+A++ L L + + +                                L +P
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120

Query: 91  QVSEDGKAHPFKINLE----------SEPQEFKPIGTAHN---------RRAQPFVAAAN 131
             S + +A P                S P  F  +  A +          +  P  A   
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180

Query: 132 IDDKRQVVSA---SYNSPIGLYSTSNIQD-------ALHGQLRGL-IPSSPQNEPTASVP 180
           +  K    S+    YN+PIGLYS   +++       +L G+  G+ +P         +V 
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKDLAVD 240

Query: 181 PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
             S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 241 SASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 21/51 (41%), Positives = 27/51 (52%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           PLC KC + I+G V+ A  +  H  CFVCA C        +   +GE YCE
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 658



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 240 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           + R PLC  C + I G  + A  +  HPE F CA C  +L    +   +  +YCE
Sbjct: 545 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 599



 Score = 32.0 bits (71), Expect = 0.74
 Identities = 11/32 (34%), Positives = 20/32 (62%)

Query: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
           H  CF+CA C++NL+ + ++  +    C+ HA
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 722


>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
          Length = 222

 Score = 98.2 bits (243), Expect = 8e-21
 Identities = 56/133 (42%), Positives = 75/133 (56%), Gaps = 8/133 (6%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQ 124
           AQ++I+A   +L L + R +     PQ +    A P +         F P   + N+ A+
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYT-------FAP-SVSLNKTAR 117

Query: 125 PFVAAANIDDKRQ 137
           PF A    D   Q
Sbjct: 118 PFGAPPPADSAPQ 130


>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
          Length = 278

 Score = 95.1 bits (235), Expect = 7e-20
 Identities = 72/246 (29%), Positives = 111/246 (45%), Gaps = 37/246 (15%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDR----------GETHLWSPQVSEDGKAHPFKINLESEPQ 110
            HA+AQ +I+ +   L L++DR          G++ L        G    +  +  S   
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVLATRFQGSVRTYTESQSSLRS 120

Query: 111 EFKPIGTAHNRRAQPF---------VAAANIDDKRQVVSASYNSP----IGLYSTSNIQD 157
            +    +   R   PF            A I    Q ++ S   P    +        + 
Sbjct: 121 SYSSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAADRLSYSGRPGSRQ 180

Query: 158 ALHGQL--RGLIPSSPQNEPTASVP------------PESDVYRMLHDNRNEPTQPRQSG 203
           A  G+     ++   P   P +S P             +S+V++ML +NR     PRQS 
Sbjct: 181 AGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEVFKMLQENREGRAAPRQSS 240

Query: 204 SFRVLQ 209
           SFR+LQ
Sbjct: 241 SFRLLQ 246


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 67/206 (32%), Positives = 96/206 (46%), Gaps = 41/206 (19%)

Query: 4   TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
           +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5   SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64  DAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQE-FKPI------- 115
           +AQ++IK     L + + R          S   K  P  +  + EP+E  KP+       
Sbjct: 65  EAQNKIKGCTGSLNMTLQR---------ASAAPKPEPVPVQ-KGEPKEVVKPVPITSPAV 114

Query: 116 -------GTAHNRRAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIP 168
                    A+N+  +PF + ++          S  SP   ++ ++   + H        
Sbjct: 115 SKVTSTNNMAYNKAPRPFGSVSS------PKVTSIPSPSSAFTPAHATTSSH-------- 160

Query: 169 SSPQNEPTASVPPESDVYRMLHDNRN 194
           +SP   P A+V P       LH N N
Sbjct: 161 ASP--SPVAAVTPPLFAASGLHANAN 184



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCET 295
           P C +C   I+G V+ A  +  H  CFVC  C   ++   +   +GE YCET
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCET 528



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 21/54 (38%), Positives = 27/54 (50%)

Query: 241 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           +R P+C  C   I G  + A  K  HPE F CA C   +   G+   +G LYCE
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCE 468


>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
          Length = 214

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 41/79 (51%), Positives = 53/79 (67%)

Query: 4  TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
          +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5  SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64 DAQDRIKAAAHQLCLKIDR 82
          +AQ++IK     L + + R
Sbjct: 65 EAQNKIKGCTGSLNMTLQR 83


>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
          Length = 234

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 41/79 (51%), Positives = 53/79 (67%)

Query: 4  TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
          +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5  SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64 DAQDRIKAAAHQLCLKIDR 82
          +AQ++IK     L + + R
Sbjct: 65 EAQNKIKGCTGSLNMTLQR 83


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score = 87.4 bits (215), Expect = 1e-17
 Identities = 41/79 (51%), Positives = 53/79 (67%)

Query: 4  TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
          +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5  SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64 DAQDRIKAAAHQLCLKIDR 82
          +AQ++IK     L + + R
Sbjct: 65 EAQNKIKGCTGSLNMTLQR 83



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCET 295
           P C +C   I+G V+ A  +  H  CFVC  C   ++   +   +GE YCET
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCET 419



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 21/54 (38%), Positives = 27/54 (50%)

Query: 241 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
           +R P+C  C   I G  + A  K  HPE F CA C   +   G+   +G LYCE
Sbjct: 306 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCE 359


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 65.5 bits (158), Expect = 6e-11
 Identities = 66/235 (28%), Positives = 95/235 (40%), Gaps = 32/235 (13%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V L G APWGFRL GG +  +PL +++I   S+A  A L   D +LAI+G    +++HA 
Sbjct: 9   VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68

Query: 65  AQDRIKAAAHQLCLKIDR--GETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRR 122
           A   I A+ +QL L + R   E  + SP        H  ++     P   +P G    + 
Sbjct: 69  AMSLIDASGNQLVLTVQRLADEGPVQSP------SPHELQVLSPLSPLSPEPPGAPVPQP 122

Query: 123 AQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSPQ----NEPTAS 178
            QP    +  D +              Y      DA  G      P  P+      PT  
Sbjct: 123 LQPGSLRSPPDSE-------------AYYGETDSDA-DGPATQEKPRRPRRRGPTRPTPP 168

Query: 179 VPPESDVYRMLHDNRNEPTQ----PRQSGSFRVLQGMVDDGSDDRPAGTRSVRAP 229
             P  +VY  L D+  EP      P   G  RV     +DG+  +P    ++  P
Sbjct: 169 GAPPDEVY--LSDSPAEPAPTIPGPPSQGDSRVSSPSWEDGAALQPPPAEALLLP 221


>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
          Length = 1109

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
          Length = 1093

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
          Length = 1261

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAAN-LCPGDVILAIDGFGTESMTHA 63
           V L G APWGF L GG +  +PLVIT+I  GSKAAA + L  GD I+ I+  G       
Sbjct: 29  VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGF-RQ 87

Query: 64  DAQDRIKAAAHQLCLKIDRGETHLWSP 90
           +A   +K +   L L + R     W P
Sbjct: 88  EAICLVKGSHKTLKLVVKRRSELGWRP 114


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 245 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 293
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 290
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.010
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 246 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 277
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.19
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 240 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 298
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 299 AR 300
           A+
Sbjct: 206 AK 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.135    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,108,010
Number of Sequences: 37866
Number of extensions: 692893
Number of successful extensions: 2278
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 164
Number of HSP's successfully gapped in prelim test: 69
Number of HSP's that attempted gapping in prelim test: 1828
Number of HSP's gapped (non-prelim): 495
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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