Guide to the Human Genome
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Search of human proteins with 166235176

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo
sapiens]
         (364 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]    756   0.0  
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]    540   e-154
gi|13994151 PDZ and LIM domain 1 [Homo sapiens]                       308   5e-84
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]             255   5e-68
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]             161   1e-39
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]             140   2e-33
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]            135   7e-32
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]            131   8e-31
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]            131   8e-31
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]            114   1e-25
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]             114   1e-25
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]            102   4e-22
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]              99   8e-21
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]              99   8e-21
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]              96   5e-20
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]              96   5e-20
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]             91   1e-18
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]              87   2e-17
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]              87   2e-17
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]              65   1e-10
gi|193083191 synaptopodin 2 isoform c [Homo sapiens]                   59   7e-09
gi|193083185 synaptopodin 2 isoform b [Homo sapiens]                   59   7e-09
gi|193083183 synaptopodin 2 isoform a [Homo sapiens]                   59   7e-09
gi|4502175 apical protein of Xenopus-like [Homo sapiens]               56   4e-08
gi|194272207 actin binding LIM protein family, member 2 isoform ...    53   5e-07
gi|153792514 actin binding LIM protein family, member 2 isoform ...    53   5e-07
gi|194272204 actin binding LIM protein family, member 2 isoform ...    53   5e-07
gi|194272202 actin binding LIM protein family, member 2 isoform ...    53   5e-07
gi|194272200 actin binding LIM protein family, member 2 isoform ...    53   5e-07
gi|194272198 actin binding LIM protein family, member 2 isoform ...    53   5e-07

>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
          Length = 364

 Score =  756 bits (1951), Expect = 0.0
 Identities = 364/364 (100%), Positives = 364/364 (100%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
Sbjct: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN
Sbjct: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
           IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL
Sbjct: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180

Query: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN 240
           PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN
Sbjct: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN 240

Query: 241 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 300
           RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG
Sbjct: 241 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 300

Query: 301 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 360
           IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL
Sbjct: 301 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 360

Query: 361 YPKA 364
           YPKA
Sbjct: 361 YPKA 364


>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
          Length = 316

 Score =  540 bits (1391), Expect = e-154
 Identities = 275/364 (75%), Positives = 288/364 (79%), Gaps = 48/364 (13%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM
Sbjct: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQ+       HN
Sbjct: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHN 120

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
            R +PFV                                           A NI  + + 
Sbjct: 121 RRAQPFVA------------------------------------------AANIDDKRQ- 137

Query: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPESDVYRMLHDN 240
               +V A +N+P+ LYS  NI + L GQ+   +  +P  +EPTASVPPESDVYRMLHDN
Sbjct: 138 ----VVSASYNSPIGLYSTSNIQDALHGQLRGLIPSSP-QNEPTASVPPESDVYRMLHDN 192

Query: 241 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 300
           RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG
Sbjct: 193 RNEPTQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPVTKVHGGSGGAQRMPLCDKCGSG 252

Query: 301 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 360
           IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL
Sbjct: 253 IVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTKPPEGYDTVTL 312

Query: 361 YPKA 364
           YPKA
Sbjct: 313 YPKA 316


>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
          Length = 329

 Score =  308 bits (789), Expect = 5e-84
 Identities = 164/373 (43%), Positives = 219/373 (58%), Gaps = 59/373 (15%)

Query: 3   QTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTH 62
           Q + L GP PWGFRL GG DF QPL I+R+TPGSKAA ANLC GDVI AIDG  T +MTH
Sbjct: 4   QQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTH 63

Query: 63  ADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHNIR 122
            +AQ+RIK     L L + R E  +WSP V+E+GK HP+K+NL SEPQ+  +    HN  
Sbjct: 64  LEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRS 123

Query: 123 PKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMELPG 182
             PF                     ++P+S +T                           
Sbjct: 124 AMPFT--------------------ASPASSTT--------------------------- 136

Query: 183 VKIVHAQFNTPMQLYSDDNI------METLQGQVSTALGETPL-MSEPTAS--VPPESDV 233
            +++  Q+N P  LYS +NI      +E+            PL  ++P +S  +  ES+V
Sbjct: 137 ARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQPPSSLVIDKESEV 196

Query: 234 YRMLHDNRNEPTQPRQSGSFRVLQGMVDD---GSDDRPAGTRSVRAPVTKVHGGSGGAQR 290
           Y+ML + +     P+QS SF VLQ +++    G  ++P+G RSV+APVTKV    G AQ+
Sbjct: 197 YKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAPVTKVAASIGNAQK 256

Query: 291 MPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARARTK 350
           +P+CDKCG+GIVG  VK RD++RHPEC+VC DC  NLKQKG+FF+E ++YCE HAR R  
Sbjct: 257 LPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHARERVT 316

Query: 351 PPEGYDTVTLYPK 363
           PPEGY+ VT++PK
Sbjct: 317 PPEGYEVVTVFPK 329


>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
          Length = 330

 Score =  255 bits (651), Expect = 5e-68
 Identities = 152/377 (40%), Positives = 198/377 (52%), Gaps = 65/377 (17%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MP +V L GP+PWGFRL GG DF+ PL I+R+  GSKAA A LCPGD+I AI+G  TE M
Sbjct: 1   MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ+RIK     L L + R E   W P   +D KA   +I+++ E QDG+    +  
Sbjct: 61  THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGSPTTSRR- 118

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
                            PSG   G     PS  S                 P  P+    
Sbjct: 119 -----------------PSGTGTGPEDGRPSLGSPYGQ------------PPRFPVP--- 146

Query: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPE--------SD 232
                             + +   TL  Q+ST     P  ++P   +P          S+
Sbjct: 147 -----------------HNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSE 189

Query: 233 VYRMLHDNRNEPT--QPRQSGSFRVLQGMVDDGSDDR---PAGTRSVRAPVTKVHGGSGG 287
           VYRML +   EP   +P+QSGSFR LQGM++ G       P G R+++   +K+     G
Sbjct: 190 VYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGDWPGPGGPRNLKPTASKLGAPLSG 248

Query: 288 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHARA 347
            Q +P C +CG GIVG +VKARDK  HPECF+C+DC LNLKQ+GYFF++  LYCE+HA+A
Sbjct: 249 LQGLPECTRCGHGIVGTIVKARDKLYHPECFMCSDCGLNLKQRGYFFLDERLYCESHAKA 308

Query: 348 RTKPPEGYDTVTLYPKA 364
           R KPPEGYD V +YP A
Sbjct: 309 RVKPPEGYDVVAVYPNA 325


>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
          Length = 352

 Score =  161 bits (407), Expect = 1e-39
 Identities = 116/370 (31%), Positives = 184/370 (49%), Gaps = 43/370 (11%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSP-QVSEDGKAHPFKINLESEPQDGNYFEHKH 119
            HA+AQ +I+ +   L L++DR +    SP Q + D          +   +   Y E + 
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQAT--SPGQTNGDSSLEVLATRFQGSVR--TYTESQS 116

Query: 120 NIRPKPFVIPGRSSGCSTPSGID--CGSGRSTPSSVSTVSTICPGDLKVAAKL-----AP 172
           ++R          S  S+P+ +    GS  S P S S+++    G+  ++        +P
Sbjct: 117 SLR----------SSYSSPTSLSPRAGSPFSPPPSSSSLT----GEAAISRSFQSLACSP 162

Query: 173 NIPLEMEL-----PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASV 227
            +P    L     PG +             + D+ +  L            + SE  + +
Sbjct: 163 GLPAADRLSYSGRPGSRQAGLG-------RAGDSAVLVLPPSPGPRSSRPSMDSEGGSLL 215

Query: 228 PPE-SDVYRMLHDNRNEPTQPRQSGSFRVLQGMVD-DGSDDRPAGTRSVRAPVTKVHGGS 285
             E S+V++ML +NR     PRQS SFR+LQ  ++ +     PA   S  +P + +    
Sbjct: 216 LDEDSEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASR 275

Query: 286 GGAQ--RMPLCDKCGSGIVGAVVKARD-KYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
             A   ++  C+KC + I    V+ ++ +YRHP C+ CADC LNLK +G+F++  ELYCE
Sbjct: 276 ALATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFWVGDELYCE 335

Query: 343 THARARTKPP 352
            HAR R   P
Sbjct: 336 KHARQRYSAP 345


>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
          Length = 366

 Score =  140 bits (353), Expect = 2e-33
 Identities = 105/352 (29%), Positives = 173/352 (49%), Gaps = 43/352 (12%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSP-QVSEDGKAHPFKINLESEPQDGNYFEHKH 119
            HA+AQ +I+ +   L L++DR +    SP Q + D          +   +   Y E + 
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQA--TSPGQTNGDSSLEVLATRFQGSVR--TYTESQS 116

Query: 120 NIRPKPFVIPGRSSGCSTPSGID--CGSGRSTPSSVSTVSTICPGDLKVAAKL-----AP 172
           ++R          S  S+P+ +    GS  S P S S+++    G+  ++        +P
Sbjct: 117 SLR----------SSYSSPTSLSPRAGSPFSPPPSSSSLT----GEAAISRSFQSLACSP 162

Query: 173 NIPLEMEL-----PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSE-PTAS 226
            +P    L     PG +             + D+ +  L            + SE  +  
Sbjct: 163 GLPAADRLSYSGRPGSRQAGLG-------RAGDSAVLVLPPSPGPRSSRPSMDSEGGSLL 215

Query: 227 VPPESDVYRMLHDNRNEPTQPRQSGSFRVLQGMVD-DGSDDRPAGTRSVRAPVTKVHGGS 285
           +  +S+V++ML +NR     PRQS SFR+LQ  ++ +     PA   S  +P + +    
Sbjct: 216 LDEDSEVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSLPASR 275

Query: 286 GGA--QRMPLCDKCGSGIVGAVVKARD-KYRHPECFVCADCNLNLKQKGYFF 334
             A   ++  C+KC + I    V+ ++ +YRHP C+ CADC LNLK +G+F+
Sbjct: 276 ALATPPKLHTCEKCSTSIANQAVRIQEGRYRHPGCYTCADCGLNLKMRGHFW 327


>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
          Length = 246

 Score =  135 bits (339), Expect = 7e-32
 Identities = 97/288 (33%), Positives = 130/288 (45%), Gaps = 62/288 (21%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           MP +V L GP+PWGFRL GG DF+ PL I+R+  GSKAA A LCPGD+I AI+G  TE M
Sbjct: 1   MPHSVTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ+RIK     L L + R E   W P   +D KA   +I+++ E QDG+       
Sbjct: 61  THLEAQNRIKGCHDHLTLSVSRPEGRSW-PSAPDDSKAQAHRIHIDPEIQDGS------- 112

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
                       +    PSG   G     PS  S                 P  P+    
Sbjct: 113 -----------PTTSRRPSGTGTGPEDGRPSLGSPYGQ------------PPRFPVP--- 146

Query: 181 PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVPPE--------SD 232
                             + +   TL  Q+ST     P  ++P   +P          S+
Sbjct: 147 -----------------HNGSSEATLPAQMSTLHVSPPPSADPARGLPRSRDCRVDLGSE 189

Query: 233 VYRMLHDNRNEP--TQPRQSGSFRVLQGMVDDGSDDRPAGTRSVRAPV 278
           VYRML +   EP   +P+QSGSFR LQGM++ G    P+      + +
Sbjct: 190 VYRMLREPA-EPVAAEPKQSGSFRYLQGMLEAGEGGAPSSRHGTSSTI 236


>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
          Length = 283

 Score =  131 bits (330), Expect = 8e-31
 Identities = 94/275 (34%), Positives = 140/275 (50%), Gaps = 57/275 (20%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ++IK+A++ L L + + +               P  I+  + P           
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSK--------------RPIPISTTAPPVQ--------- 97

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
             P P VIP +    ++P+  D    R  PS++              + L+ + P+E++ 
Sbjct: 98  -TPLP-VIPHQKVVVNSPANADY-QERFNPSALKD------------SALSTHKPIEVKG 142

Query: 181 PGVK--IVHAQFNTPMQLYSDDNIMETLQGQV----STALGETPLMSEPTASVPPESDVY 234
            G K  I+HAQ+NTP+ +YS D IM+ + GQ     S   G  P+      +V   S VY
Sbjct: 143 LGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKD---LAVDSASPVY 199

Query: 235 RMLHDNRNEP----------TQPRQSGSFRVLQGM 259
           + +  ++N+P          +   QS SFR+L  M
Sbjct: 200 QAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234


>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
          Length = 617

 Score =  131 bits (330), Expect = 8e-31
 Identities = 94/275 (34%), Positives = 140/275 (50%), Gaps = 57/275 (20%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ++IK+A++ L L + + +               P  I+  + P           
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSK--------------RPIPISTTAPPVQ--------- 97

Query: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
             P P VIP +    ++P+  D    R  PS++              + L+ + P+E++ 
Sbjct: 98  -TPLP-VIPHQKVVVNSPANADY-QERFNPSALKD------------SALSTHKPIEVKG 142

Query: 181 PGVK--IVHAQFNTPMQLYSDDNIMETLQGQV----STALGETPLMSEPTASVPPESDVY 234
            G K  I+HAQ+NTP+ +YS D IM+ + GQ     S   G  P+      +V   S VY
Sbjct: 143 LGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKD---LAVDSASPVY 199

Query: 235 RMLHDNRNEP----------TQPRQSGSFRVLQGM 259
           + +  ++N+P          +   QS SFR+L  M
Sbjct: 200 QAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 21/51 (41%), Positives = 27/51 (52%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           PLC KC + I+G V+ A  +  H  CFVCA C        +   +GE YCE
Sbjct: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 288 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           + R PLC  C + I G  + A  +  HPE F CA C  +L    +   +  +YCE
Sbjct: 435 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 11/32 (34%), Positives = 20/32 (62%)

Query: 314 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 345
           H  CF+CA C++NL+ + ++  +    C+ HA
Sbjct: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612


>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
          Length = 330

 Score =  114 bits (286), Expect = 1e-25
 Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 30/285 (10%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ++IK+A++ L L + + +  +    +S         + +    +D     +   
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPI---PISTTAPPVQTPLPVIPHQKDPALDTNGSL 117

Query: 121 IRPKPFVIPGRSSGCS-----TPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIP 175
           + P P      S G        P+     S  S  SS++  S   P    + AK +P   
Sbjct: 118 VAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGA 177

Query: 176 LEM----ELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVP--- 228
            ++     LPG      Q+N P+ LYS + + E  Q    +  G+   +  P  S+P   
Sbjct: 178 RDLLGPKALPG-SSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKD 236

Query: 229 ----PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 259
                 S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 237 LAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281


>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
          Length = 727

 Score =  114 bits (286), Expect = 1e-25
 Identities = 89/285 (31%), Positives = 135/285 (47%), Gaps = 30/285 (10%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L  GD+++AIDG  T++M
Sbjct: 1   MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
           TH +AQ++IK+A++ L L + + +  +    +S         + +    +D     +   
Sbjct: 61  THLEAQNKIKSASYNLSLTLQKSKRPI---PISTTAPPVQTPLPVIPHQKDPALDTNGSL 117

Query: 121 IRPKPFVIPGRSSGCS-----TPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIP 175
           + P P      S G        P+     S  S  SS++  S   P    + AK +P   
Sbjct: 118 VAPSPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGA 177

Query: 176 LEM----ELPGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSEPTASVP--- 228
            ++     LPG      Q+N P+ LYS + + E  Q    +  G+   +  P  S+P   
Sbjct: 178 RDLLGPKALPG-SSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLPGGSLPIKD 236

Query: 229 ----PESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 259
                 S VY+ +  ++N+P          +   QS SFR+L  M
Sbjct: 237 LAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 281



 Score = 45.4 bits (106), Expect = 8e-05
 Identities = 21/51 (41%), Positives = 27/51 (52%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           PLC KC + I+G V+ A  +  H  CFVCA C        +   +GE YCE
Sbjct: 608 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 658



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 19/55 (34%), Positives = 27/55 (49%)

Query: 288 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           + R PLC  C + I G  + A  +  HPE F CA C  +L    +   +  +YCE
Sbjct: 545 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 599



 Score = 32.0 bits (71), Expect = 0.89
 Identities = 11/32 (34%), Positives = 20/32 (62%)

Query: 314 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 345
           H  CF+CA C++NL+ + ++  +    C+ HA
Sbjct: 691 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 722


>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
          Length = 487

 Score =  102 bits (255), Expect = 4e-22
 Identities = 98/362 (27%), Positives = 146/362 (40%), Gaps = 30/362 (8%)

Query: 4   TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
           +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5   SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64  DAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQD--------GNYF 115
           +AQ++IK     L + + R      +P+        P   ++ SE           G+  
Sbjct: 65  EAQNKIKGCTGSLNMTLQRASA---APKPEPVPVQKPTVTSVCSETSQELAEGQRRGSQG 121

Query: 116 EHK-HNIRPKPFVIPGRSSGCSTPSGIDCGSGR---STPSSVSTVSTICPGDLKVAAKLA 171
           + K  N  P+  ++   +     P+  D    R    T        T      ++ A++ 
Sbjct: 122 DSKQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQIT 181

Query: 172 PNIPL-EMELPGVKIVHAQFNTPMQLYSD----DNIMETLQGQVSTALGETPLMSEPTAS 226
               L E E    K  +       QL S      ++ E+L    S   G T L +     
Sbjct: 182 GTEHLKESEADNTKKANNSQEPSPQLASSVASTRSMPESLDSPTSGRPGVTSLTAAAAFK 241

Query: 227 VPPESDVYR---MLHDNRNEPTQPRQSGSFRVLQGMVDDGS---DDRPAGTRSVRAPVTK 280
               + V +       N+  P+  R S S      +    S     +P+   ++      
Sbjct: 242 PVGSTGVIKSPSWQRPNQGVPSTGRISNSATYSGSVAPANSALGQTQPSDQDTLVQRAEH 301

Query: 281 VHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELY 340
           +  G    +R P+C  C   I G  + A  K  HPE F CA C   +   G+   +G LY
Sbjct: 302 IPAG----KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALY 357

Query: 341 CE 342
           CE
Sbjct: 358 CE 359



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCET 343
           P C +C   I+G V+ A  +  H  CFVC  C   ++   +   +GE YCET
Sbjct: 368 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCET 419


>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
          Length = 278

 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 80/271 (29%), Positives = 130/271 (47%), Gaps = 39/271 (14%)

Query: 1   MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
           M  TV + GPAPWGFR++GG DF+ P+++T++    KA  A+L PGD+I+AI+G   E M
Sbjct: 1   MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGM 60

Query: 61  THADAQDRIKAAAHQLCLKIDRGETHLWSP-QVSEDGKAHPFKINLESEPQDGNYFEHKH 119
            HA+AQ +I+ +   L L++DR +    SP Q + D          +   +   Y E + 
Sbjct: 61  LHAEAQSKIRQSPSPLRLQLDRSQA--TSPGQTNGDSSLEVLATRFQGSVR--TYTESQS 116

Query: 120 NIRPKPFVIPGRSSGCSTPSGID--CGSGRSTPSSVSTVSTICPGDLKVAAKL-----AP 172
           ++R          S  S+P+ +    GS  S P S S+++    G+  ++        +P
Sbjct: 117 SLR----------SSYSSPTSLSPRAGSPFSPPPSSSSLT----GEAAISRSFQSLACSP 162

Query: 173 NIPLEMEL-----PGVKIVHAQFNTPMQLYSDDNIMETLQGQVSTALGETPLMSE-PTAS 226
            +P    L     PG +             + D+ +  L            + SE  +  
Sbjct: 163 GLPAADRLSYSGRPGSRQAGLG-------RAGDSAVLVLPPSPGPRSSRPSMDSEGGSLL 215

Query: 227 VPPESDVYRMLHDNRNEPTQPRQSGSFRVLQ 257
           +  +S+V++ML +NR     PRQS SFR+LQ
Sbjct: 216 LDEDSEVFKMLQENREGRAAPRQSSSFRLLQ 246


>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
          Length = 423

 Score = 98.6 bits (244), Expect = 8e-21
 Identities = 53/128 (41%), Positives = 73/128 (57%), Gaps = 1/128 (0%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHNIRPK 124
           AQ++I+A   +L L + R +     PQ  +     P +  L  +       E+  + RP+
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKVQTPDKQPLR-PLVPDASKQRLMENTEDWRPR 124

Query: 125 PFVIPGRS 132
           P     RS
Sbjct: 125 PGTGQSRS 132



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 24/71 (33%), Positives = 36/71 (50%)

Query: 271 TRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQK 330
           T  V+A    V GG     + P+C +C   I G  + A     HPE FVC+ C   L++ 
Sbjct: 225 TSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEG 284

Query: 331 GYFFIEGELYC 341
           G+F  +G ++C
Sbjct: 285 GFFEEKGAIFC 295



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           P C KC   I G ++ A     H  CF CA C   ++ + ++  EG  YCE
Sbjct: 305 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 355



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 314 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 345
           H  CFVCA C +NL+ K ++  +    C++HA
Sbjct: 388 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 419


>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
          Length = 222

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 47/96 (48%), Positives = 62/96 (64%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHP 100
           AQ++I+A   +L L + R +     PQ +    A P
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADP 101


>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
          Length = 457

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 47/96 (48%), Positives = 62/96 (64%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A +  GD +L+IDG    S+TH +
Sbjct: 6   VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHP 100
           AQ++I+A   +L L + R +     PQ +    A P
Sbjct: 66  AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADP 101



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 24/71 (33%), Positives = 36/71 (50%)

Query: 271 TRSVRAPVTKVHGGSGGAQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQK 330
           T  V+A    V GG     + P+C +C   I G  + A     HPE FVC+ C   L++ 
Sbjct: 259 TSIVQAAAGGVPGGGSNNGKTPVCHQCHKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEG 318

Query: 331 GYFFIEGELYC 341
           G+F  +G ++C
Sbjct: 319 GFFEEKGAIFC 329



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 18/51 (35%), Positives = 25/51 (49%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           P C KC   I G ++ A     H  CF CA C   ++ + ++  EG  YCE
Sbjct: 339 PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCE 389



 Score = 34.7 bits (78), Expect = 0.14
 Identities = 13/32 (40%), Positives = 20/32 (62%)

Query: 314 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 345
           H  CFVCA C +NL+ K ++  +    C++HA
Sbjct: 422 HDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 453


>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
          Length = 596

 Score = 91.3 bits (225), Expect = 1e-18
 Identities = 84/288 (29%), Positives = 117/288 (40%), Gaps = 41/288 (14%)

Query: 4   TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
           +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5   SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64  DAQDRIKAAAHQLCLKIDRGE-THLWSPQVSEDGK----AHPFKINLESEPQDGNYFEHK 118
           +AQ++IK     L + + R        P   + G+      P  I   +  +  +     
Sbjct: 65  EAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNNMA 124

Query: 119 HNIRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAP------ 172
           +N  P+PF         S PS     S   TP+  +T S   P    VAA   P      
Sbjct: 125 YNKAPRPFGSVSSPKVTSIPS----PSSAFTPAHATTSSHASPS--PVAAVTPPLFAASG 178

Query: 173 -----NIPLEMELPGVKIVHAQFNTPMQ----LYSDDNIMETLQGQVSTALGETPLMSEP 223
                N+  +     +       N P Q        +   E  +GQ   + G++   + P
Sbjct: 179 LHANANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGP 238

Query: 224 TAS-----------VPPESDVYRMLHDNRNEPTQPR----QSGSFRVL 256
                         VP  SD  +       E  +PR    QS SFR+L
Sbjct: 239 PRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRIL 286



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCET 343
           P C +C   I+G V+ A  +  H  CFVC  C   ++   +   +GE YCET
Sbjct: 477 PECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYCET 528



 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 21/54 (38%), Positives = 27/54 (50%)

Query: 289 QRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
           +R P+C  C   I G  + A  K  HPE F CA C   +   G+   +G LYCE
Sbjct: 415 KRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALYCE 468


>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
          Length = 214

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 41/79 (51%), Positives = 53/79 (67%)

Query: 4  TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
          +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5  SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64 DAQDRIKAAAHQLCLKIDR 82
          +AQ++IK     L + + R
Sbjct: 65 EAQNKIKGCTGSLNMTLQR 83


>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
          Length = 234

 Score = 87.4 bits (215), Expect = 2e-17
 Identities = 41/79 (51%), Positives = 53/79 (67%)

Query: 4  TVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHA 63
          +V L GPAPWGFRL GG DFN PL I+ +  G KAA AN+  GDV+L+IDG   + MTH 
Sbjct: 5  SVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMTHL 64

Query: 64 DAQDRIKAAAHQLCLKIDR 82
          +AQ++IK     L + + R
Sbjct: 65 EAQNKIKGCTGSLNMTLQR 83


>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
          Length = 977

 Score = 64.7 bits (156), Expect = 1e-10
 Identities = 45/148 (30%), Positives = 67/148 (45%), Gaps = 22/148 (14%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
           V L G APWGFRL GG +  +PL +++I   S+A  A L   D +LAI+G    +++HA 
Sbjct: 9   VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68

Query: 65  AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHNIRPK 124
           A   I A+ +QL L + R         ++++G            P +         + P+
Sbjct: 69  AMSLIDASGNQLVLTVQR---------LADEGPVQ------SPSPHELQVLSPLSPLSPE 113

Query: 125 PFVIPGRSSGCSTPSGIDCGSGRSTPSS 152
           P        G   P  +  GS RS P S
Sbjct: 114 P-------PGAPVPQPLQPGSLRSPPDS 134


>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
          Length = 1109

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
          Length = 1093

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
          Length = 1261

 Score = 58.9 bits (141), Expect = 7e-09
 Identities = 29/91 (31%), Positives = 51/91 (56%)

Query: 5  VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
          + + G APWGFRL GG +  QPL + +I   SKA+ + LC GD +++I+G     +T+ +
Sbjct: 9  ISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADLTYPE 68

Query: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSED 95
              +++    L + I R  + +    +SE+
Sbjct: 69 VIKLMESITDSLQMLIKRPSSGISEALISEN 99


>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
          Length = 1616

 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)

Query: 5   VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAAN-LCPGDVILAIDGFGTESMTHA 63
           V L G APWGF L GG +  +PLVIT+I  GSKAAA + L  GD I+ I+  G       
Sbjct: 29  VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGF-RQ 87

Query: 64  DAQDRIKAAAHQLCLKIDRGETHLWSP 90
           +A   +K +   L L + R     W P
Sbjct: 88  EAICLVKGSHKTLKLVVKRRSELGWRP 114


>gi|194272207 actin binding LIM protein family, member 2 isoform 7
           [Homo sapiens]
          Length = 470

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


>gi|153792514 actin binding LIM protein family, member 2 isoform 6
           [Homo sapiens]
          Length = 521

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


>gi|194272204 actin binding LIM protein family, member 2 isoform 5
           [Homo sapiens]
          Length = 531

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


>gi|194272202 actin binding LIM protein family, member 2 isoform 4
           [Homo sapiens]
          Length = 559

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


>gi|194272200 actin binding LIM protein family, member 2 isoform 3
           [Homo sapiens]
          Length = 572

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


>gi|194272198 actin binding LIM protein family, member 2 isoform 2
           [Homo sapiens]
          Length = 611

 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 21/49 (42%), Positives = 31/49 (63%)

Query: 293 LCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYC 341
           LC+ CG+   G V++ +DKY H +CFVC  C  +L + G+F  +GE  C
Sbjct: 23  LCNTCGNVCKGEVLRVQDKYFHIKCFVCKACGCDLAEGGFFVRQGEYIC 71



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 7/45 (15%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGE 338
           CD C   I G V++A +K+ HP C +C  C       G  F EGE
Sbjct: 212 CDSCEKYITGRVLEAGEKHYHPSCALCVRC-------GQMFAEGE 249



 Score = 38.1 bits (87), Expect = 0.012
 Identities = 17/32 (53%), Positives = 18/32 (56%)

Query: 294 CDKCGSGIVGAVVKARDKYRHPECFVCADCNL 325
           C  C   I G VV A  K  HP+CFVCA C L
Sbjct: 83  CFSCDQFIEGEVVSALGKTYHPDCFVCAVCRL 114



 Score = 33.9 bits (76), Expect = 0.23
 Identities = 21/62 (33%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 288 AQRMPLCDKCGSGIV-GAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCETHAR 346
           +Q +  C  CG+ I  G  + A DK+ H  CF C  C   L    Y   +G  YCE    
Sbjct: 147 SQGLRSCGGCGTEIKNGQALVALDKHWHLGCFKCKSCG-KLLNAEYISKDGLPYCEADYH 205

Query: 347 AR 348
           A+
Sbjct: 206 AK 207


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,748,680
Number of Sequences: 37866
Number of extensions: 847178
Number of successful extensions: 2688
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 74
Number of HSP's that attempted gapping in prelim test: 2217
Number of HSP's gapped (non-prelim): 515
length of query: 364
length of database: 18,247,518
effective HSP length: 104
effective length of query: 260
effective length of database: 14,309,454
effective search space: 3720458040
effective search space used: 3720458040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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