Guide to the Human Genome
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Search of human proteins with 154759255

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
         (1125 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|154759255 collagen, type XXVIII precursor [Homo sapiens]          2345   0.0  
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      463   e-130
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   460   e-129
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     459   e-129
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         452   e-126
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     448   e-125
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   447   e-125
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   447   e-125
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   447   e-125
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   446   e-125
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   446   e-125
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      446   e-125
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   442   e-124
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   442   e-124
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   442   e-124
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   441   e-123
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   441   e-123
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   441   e-123
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        435   e-121
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     434   e-121
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]              433   e-121
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   431   e-120
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   431   e-120
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...   431   e-120
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    431   e-120
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       430   e-120
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              426   e-119
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    424   e-118
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   422   e-117
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        420   e-117

>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 2345 bits (6078), Expect = 0.0
 Identities = 1125/1125 (100%), Positives = 1125/1125 (100%)

Query: 1    MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK 60
            MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK
Sbjct: 1    MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK 60

Query: 61   IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK 120
            IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK
Sbjct: 61   IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK 120

Query: 121  VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI 180
            VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI
Sbjct: 121  VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI 180

Query: 181  SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC 240
            SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC
Sbjct: 181  SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC 240

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC
Sbjct: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360
            GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG
Sbjct: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360

Query: 361  QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
            QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT
Sbjct: 361  QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420

Query: 421  GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK 480
            GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK
Sbjct: 421  GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK 480

Query: 481  GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
            GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG
Sbjct: 481  GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540

Query: 541  PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR 600
            PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR
Sbjct: 541  PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR 600

Query: 601  GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660
            GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV
Sbjct: 601  GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660

Query: 661  GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720
            GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF
Sbjct: 661  GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720

Query: 721  PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
            PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK
Sbjct: 721  PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780

Query: 781  LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII 840
            LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII
Sbjct: 781  LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII 840

Query: 841  NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL 900
            NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL
Sbjct: 841  NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL 900

Query: 901  VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY 960
            VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY
Sbjct: 901  VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY 960

Query: 961  QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS 1020
            QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS
Sbjct: 961  QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS 1020

Query: 1021 ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN 1080
            ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN
Sbjct: 1021 ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN 1080

Query: 1081 CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125
            CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG
Sbjct: 1081 CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  463 bits (1192), Expect = e-130
 Identities = 280/631 (44%), Positives = 323/631 (51%), Gaps = 109/631 (17%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G PG PGP G  G  G +GERGP+G  G    KG +G  GP G PG +G  G +G  G 
Sbjct: 900  RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959

Query: 303  PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            PG KG  G PG  G       +G  G QG TGPPG PG  G QG  GE GP G  G PG 
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019

Query: 357  PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----------E 405
            PG  G+QG+ G  G+EG  G PGP G+  PG+ GP G  G PG+RGLPG          E
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGL--PGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077

Query: 406  GFPGPKGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQ 460
            G PGP G  GS G  GP G  G + I G  G  GP GP G  G PG     G  G  G+Q
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137

Query: 461  GPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPG 507
            GP+G PGP GP G              G  GSKG+ G+ GP GP GP     QGP G+PG
Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP-----QGPIGQPG 1192

Query: 508  SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRG 566
              G  G+PG  G+ G  G+KG+ G  G  GP GP G +G PGP G++G+ G  G  G  G
Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252

Query: 567  LPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGD---RGGPGIPGFKGEPG-LSIRGPKG 621
             PGP GP G PG  GP G PG    PG  G KG+    G PG+PG  G PG    RG KG
Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKG 1312

Query: 622  VQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPPGPMGLRG------------------ 659
              GP G  G PG KG    DG  G PGP G PG PGP G  G                  
Sbjct: 1313 ESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372

Query: 660  -------VGDTGAKGEPGVRGPPGPSGPRG----------VGTQGPKGDTGQ---KGLPG 699
                    G+ G  G PG RGPPGP+GP G           G +GP G TG    +G PG
Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG 1432

Query: 700  PPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGD--------- 743
             PGP G        G QG+ G  GP G PGP G  G  LPG KG+ G +G+         
Sbjct: 1433 KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG--LPGLKGDSGPKGEKGHPGLIGL 1490

Query: 744  VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            +G  G++GE G+ G PG QG  GPKG+ G+T
Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT 1521



 Score =  456 bits (1174), Expect = e-128
 Identities = 274/602 (45%), Positives = 325/602 (53%), Gaps = 87/602 (14%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG-------NAQKGEAGERGPGGIPGYKGDKGER 297
            G PG  G  G+ G  G+ G+ GPKG+ G         +KG  G+ GP G PG  GD GER
Sbjct: 604  GKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663

Query: 298  GECGKPGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
            G+ G+ G +G  G PGP G      P GP G  G+TG  G PGPKG  G +GEPGPPG  
Sbjct: 664  GDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQ 723

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE----G 406
            G+PGA     QG+ G +G  G PG  GP+G  G PG PG  GP G PG+ G PGE    G
Sbjct: 724  GNPGA-----QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG 778

Query: 407  FPGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP 462
             PGP+G  G  GP G +G  G+      KGEKG+ G  G +G MGI   G +GE G  GP
Sbjct: 779  PPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIK--GDRGEIGPPGP 836

Query: 463  IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVP 518
             G  GP+GP G+G  G  G+ G +GP G +G +G+    G  G +G  GSIG PG PG  
Sbjct: 837  RGEDGPEGPKGRG--GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN 894

Query: 519  GEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQGQRGLPGPE 571
            GE G  G  G+ G  G RGP GP G+       G+PGPKG+ G  G  G  G+RG  GP+
Sbjct: 895  GEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ 954

Query: 572  GPKGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDR 600
            GP G PG  GP G PG                   T  PGPP            GP G+R
Sbjct: 955  GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER 1014

Query: 601  GGPGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLR 658
            G PG PG  GE GL  + G +G +G  GP G PG  G  G  G PG RGLPGP G +GL+
Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074

Query: 659  G----VGDTGAKGEPGVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPGYGSQG 710
            G     G  G  G PG RGP G +GP G+    G QGP G  G+KG PG  GP   G  G
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP--QGPAG 1132

Query: 711  IKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
              G QGP G PGP G +G   PG+ G+ GE G+ G+KG KG+ GE G PG  G QGP G 
Sbjct: 1133 RDGLQGPVGLPGPAGPVGP--PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190

Query: 771  LG 772
             G
Sbjct: 1191 PG 1192



 Score =  450 bits (1157), Expect = e-126
 Identities = 279/649 (42%), Positives = 327/649 (50%), Gaps = 128/649 (19%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGD---KGERGE 299
            EKG  G PGP G  G PG +G +G  G  G   KG  GE+G  G PG+KGD   KG+RGE
Sbjct: 773  EKGGQGPPGPQGPIGYPGPRGVKGADGIRG--LKGTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             G PG +G+ G  GP G  GP G  G  GPPG+ G  G  G  G PG  GP GS G PG 
Sbjct: 831  IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890

Query: 360  GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGP 419
               G  GE+G  G PG PGP      GQ GP GP G  G RG+ G+  PGPKG  G +GP
Sbjct: 891  --PGANGEKGGRGTPGKPGP-----RGQRGPTGPRGERGPRGITGK--PGPKGNSGGDGP 941

Query: 420  TGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG- 473
             GP G +G +  +G  G  GP GP GP G  G+    G +GE G QG  GPPGP G  G 
Sbjct: 942  AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001

Query: 474  QGLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPG---------- 516
            QG  G  G +G+ G  GP GP G        G +G KG+PG  GLPG+ G          
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061

Query: 517  --VPGEDGAAGKKGEAGLPGARGPEGPPGK-------------GQPGPKGDEGKKGSKGN 561
              +PG  GA G KG  G PG  GP G PG+             G+PGP+G  G  G KG 
Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121

Query: 562  QGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPG-LSIRGP 619
             G++G   P+GP G  G+ GP G+PG + P GPPG  GD+G  G PG KG  G    +GP
Sbjct: 1122 PGEKG---PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGP 1178

Query: 620  KGVQGPRGPVGAPGLKG-DGYPGV------------PGPRGLPGPPGPMGLRGV----GD 662
             G  GP+GP+G PG  G DG PG              GPRG PGPPGP+GL+G+    G+
Sbjct: 1179 PGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238

Query: 663  TGAKGEPGVRGPPGPSGPRG----------------------VGTQGPKGDTGQKGLPGP 700
             G  G+ G  GPPGP GPRG                      VG +G  G+ G+ GLPG 
Sbjct: 1239 KGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298

Query: 701  PGPPG-YGSQGIKGEQGPQGF---PGPKGTMGH--------------------------- 729
             GPPG  G +G KGE GP G    PGPKG  G                            
Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358

Query: 730  -GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
             G PG KG+ GE G  G  G  GE G  G PGK+G  GP G  G   E+
Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407



 Score =  424 bits (1091), Expect = e-118
 Identities = 271/594 (45%), Positives = 311/594 (52%), Gaps = 70/594 (11%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNP--------GNAQKGEAGE--------------- 281
            GDPG+ GPPG  G PG  G  GP G          G    G  G                
Sbjct: 493  GDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQ 552

Query: 282  -----RGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336
                 RGP G  G  G  G  G  G  G+KG+ G     GP+GPRG+QG  GP G PG +
Sbjct: 553  ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD---VGPQGPRGVQGPPGPAGKPGRR 609

Query: 337  GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEG 395
            G  G+ G  G PG  G  G  G  G  G+ GE+G  G PG  GP   G PG  G RG +G
Sbjct: 610  GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP--PGPPGDDGERGDDG 667

Query: 396  VPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPG---- 450
              G RGLPGE  PGP+G  G +GP GP G  G++ + G+ G  G VGPQG  G PG    
Sbjct: 668  EVGPRGLPGE--PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725

Query: 451  IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGS 508
             G+QG  G QG IGPPG +GP G+ GLPG  G  G  G  G  GP G  G QGP G  G 
Sbjct: 726  PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGP 785

Query: 509  IGLPGQPGVPGED------GAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKGS 558
            IG PG  GV G D      G  G+KGE G PG +G  G  G     G PGP+G++G +G 
Sbjct: 786  IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845

Query: 559  KGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG----L 614
            KG  G  G PGP GP GE G +G  G+PG   PG  GPKG  G PG PG  GE G     
Sbjct: 846  KGRGGPNGDPGPLGPPGEKGKLGVPGLPG--YPGRQGPKGSIGFPGFPGANGEKGGRGTP 903

Query: 615  SIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVR 672
               GP+G +GP GP G  G +G  G PG  G  G  GP GP G RG  G  G  G PG +
Sbjct: 904  GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963

Query: 673  GPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGP---QGFPGPKGTM 727
            GPPGP G  G+ G  G +G+TG +G  GPPGPPG  G QG  GE GP   +G PGP G  
Sbjct: 964  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023

Query: 728  G-HGLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGLTKEE 777
            G  GLPG  G+ G +GD G  G  G+ G P   G PG +GL GP G LGL   E
Sbjct: 1024 GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077



 Score =  418 bits (1075), Expect = e-116
 Identities = 269/604 (44%), Positives = 302/604 (50%), Gaps = 82/604 (13%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGE 299
            E  KGDPG  G PG  G PG++G  G +G PG     G  G  GP G PG  G  GERG 
Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094

Query: 300  CGKPGIKGDKGSPGPYGPKGP---RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
             G  G  G  G PGP GP GP   +G  G  GP G  G  G QG  G PGP GP G PG 
Sbjct: 1095 AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154

Query: 357  PG----IGQQGIKGERGQEGRPGAPGPIGVGEP-GQPGPRGPEGVPGERGLPG-EGFPGP 410
             G    IG+ G KG +G +G  G PGP G   P GQPGP G +G PG RG  G  G  G 
Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214

Query: 411  KGEKGSEGPTGPQGLQGL----SIKGEKGDI------GPVGPQGPMGIPGI--------- 451
            +G +G  GP GP GLQGL      KGE GD+      GP GP+GP G PG          
Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274

Query: 452  -------------GSQGEQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGP 488
                         G  GE G+ G  GPPGP+G  G+          G PG KG  G  GP
Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334

Query: 489  TGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQ 546
             G  GPVG  G  GP GEPG  G  G PG  G+DG  G+ G  G  G  GP GPPGK G 
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394

Query: 547  PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP 606
            PGP G EG++G KG +G+ GL GP      PG  GP G  G   PG PGP G RG PG  
Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGP------PGKTGPIGPQGA--PGKPGPDGLRGIPGPV 1446

Query: 607  GFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGA 665
            G +G PG    GP G  GP GP G PGLKGD      GP+G  G PG +GL G  G+ G 
Sbjct: 1447 GEQGLPGSP--GPDGPPGPMGPPGLPGLKGDS-----GPKGEKGHPGLIGLIGPPGEQGE 1499

Query: 666  KGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGE 714
            KG+ G+ GP G SGP+G     G  GP G  G  GLPGPPGP G        G +G  G 
Sbjct: 1500 KGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGH 1559

Query: 715  QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
             GP G PGP G +   LP Q        D  +  D G  GE       G++   G L   
Sbjct: 1560 PGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGN-GENYVDYADGMEEIFGSLNSL 1618

Query: 775  KEEI 778
            K EI
Sbjct: 1619 KLEI 1622



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 42/161 (26%), Positives = 52/161 (32%), Gaps = 60/161 (37%)

Query: 670 GVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKG---------------- 713
           G   P  P+ P G G + P           P  PPG G+  ++G                
Sbjct: 360 GEENPDQPTDP-GAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYD 418

Query: 714 ----------EQGP----------QGFPGPKGTMGH-----------------------G 730
                     E GP          +G  GP+G  G                        G
Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG 478

Query: 731 LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771
           LPG  G  G  G VG  G++G  G PG PG  GL GP G +
Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTM 519


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  460 bits (1183), Expect = e-129
 Identities = 287/630 (45%), Positives = 336/630 (53%), Gaps = 104/630 (16%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            G+ G  GPPG+ G PG  G RG KG  GN   +GE GE+G  G PG+KGD G +G+ GKP
Sbjct: 692  GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK---GFQGNKGEPGPPGPYGSPGAPG-- 358
            G  G +G  GP GPKG  G  G  GPPG  G K   G  G  G PG PGP GS G PG  
Sbjct: 752  GAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL 811

Query: 359  --IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPR------GPEGVPGERGLP 403
              IG++G  G+ GQ G  G  GP G        G  GQPGP+      G  G+PGE+GLP
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 404  G----EGFPGPK------------------GEKGSEGPTGPQGLQG-LSIKGEKGDIGPV 440
            G     GFPGPK                  GE G +G TGP G  G L  +G+ G++GP+
Sbjct: 872  GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 441  GPQGPMGIPG-------IGSQGEQGIQGPIGPPGP---QGPAG-QGLPGSKGEVGQMGPT 489
            G +GP G PG        G +G +G +G +GPPGP   +GPAG +G PG KG  G  GPT
Sbjct: 932  GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991

Query: 490  ------GPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKK------------ 527
                  GP GPVG     G +GP G  G IGLPGQ G  G  G AGKK            
Sbjct: 992  GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPT 1051

Query: 528  GEAGLPGARGPEGPPGKGQP-GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586
            G+ G+PG  GP GPPG   P G +GD+G  G+ G++G +G  G  GP G+PGI GP G P
Sbjct: 1052 GKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHP 1111

Query: 587  GTSIPGPPGPKGDRGGPGIPGFKGEPG----LSIRGPKGVQGPRGPVGAPGLKGD----G 638
            G   PG  G +G RG PG+ G KG+ G    + + GP G+QG  GP G  G  GD    G
Sbjct: 1112 GP--PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMG 1169

Query: 639  YPGVPGPRGLPGPPGPMGL----RGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693
              G PGPRG  GP G  G      GVG  GA GE G RG  G  GP G  G  GPKGD G
Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229

Query: 694  QKGLPGP---PGPPGY----GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERG 742
            +KG  GP    GPPG     G  G KG  GP G PG  G  G     G+ G  GE G+ G
Sbjct: 1230 EKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPG 1289

Query: 743  DVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            DVG  G  G  GEPG+PG  G +GP G +G
Sbjct: 1290 DVGGPGPPGASGEPGAPGPPGKRGPSGHMG 1319



 Score =  438 bits (1127), Expect = e-122
 Identities = 271/605 (44%), Positives = 320/605 (52%), Gaps = 91/605 (15%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-------NAQKGEAGERGPGGIPGYKGDKGE 296
            +G  G PG PG  G  G +G+ GP G  G         + G  GERGP G PG  G++G 
Sbjct: 889  QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGP---PGDPGPKGFQGNKGEPGPPGPYGS 353
             G  G+ G KG+ G PGP G +GP G++G  GP   PGDPGP G +G+KG PGP G  GS
Sbjct: 949  PGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS 1008

Query: 354  PGAPG-------------------IGQQGIKGERGQEGRPGA------PGPIG-VGEPGQ 387
            PG  G                   +G  G KG RG+ G PG       PGP+G +G PG 
Sbjct: 1009 PGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGA 1068

Query: 388  PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447
             GP G EG  G+ G PG    G KG+KG  GP G  G++G +  G  G  G  G QG  G
Sbjct: 1069 AGPSGEEGDKGDVGAPGH--KGSKGDKGDAGPPGQPGIRGPA--GHPGPPGADGAQGRRG 1124

Query: 448  IPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGE 505
             PG+ G +G+ G++G +G  GP  P  QGLPG  GE G++G  G  GP G  G +GP+G 
Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGP--PGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182

Query: 506  PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR 565
             GS G PG PG  G+ GA G+KGE G  G  GP G PG   PGPKGD G+KG  G  G  
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI--PGPKGDIGEKGDSGPSGAA 1240

Query: 566  GLPGPEGPKGE------------PGIMGPFGMPGTS-IPGPPGPKGDRG---GPGIPGFK 609
            G PG +GP GE            PG +GP G PG S I G PG KGD G   GPG PG  
Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGAS 1300

Query: 610  GEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG--------- 659
            GEPG    GP G +GP G +G  G +G+ G  G PGP G PG  GPMG RG         
Sbjct: 1301 GEPGAP--GPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEG 1358

Query: 660  -------VGDTGAKGEPGVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPGY-G 707
                   VG+ G  G PG  GPPGP GP G+    G  GPKG+ G  GL G  GPPG  G
Sbjct: 1359 LRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAG 1418

Query: 708  SQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGP 767
             +G +G  G QG PGPKG      PG  G  G  G  G  G  G +G+ GS G  G  GP
Sbjct: 1419 EKGDQGLPGVQGPPGPKGD-----PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473

Query: 768  KGDLG 772
            +GD G
Sbjct: 1474 RGDTG 1478



 Score =  432 bits (1112), Expect = e-121
 Identities = 266/602 (44%), Positives = 323/602 (53%), Gaps = 74/602 (12%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            EKG  GD G  G  G PG  GERG +G PG    G+AGE GP G+ G +G  G  G  G 
Sbjct: 561  EKGQRGDFGHVGQPGPPGEDGERGAEGPPGPT--GQAGEPGPRGLLGPRGSPGPTGRPGV 618

Query: 303  PGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             GI G    KG+ GP G  GP G QG  G  G PGP+G  G  GE GPPG  G PG PG 
Sbjct: 619  TGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS 678

Query: 360  -------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE------- 405
                   G +G  GE+G +G PG+ GP     PG PGPRG +G  G RGL GE       
Sbjct: 679  DGPLGHPGHEGPTGEKGAQGPPGSAGP-----PGYPGPRGVKGTSGNRGLQGEKGEKGED 733

Query: 406  GFPGPKGE---------------KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450
            GFPG KG+               +G +GP GP+G  G +  GE+G  G  G +G +G+PG
Sbjct: 734  GFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA--GEEGPPGSAGEKGKLGVPG 791

Query: 451  I-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSI 509
            + G  G  G +G IG PGP GP G+   G  G+ GQ G  G RGP G   +G +G+PG+ 
Sbjct: 792  LPGYPGRPGPKGSIGFPGPLGPIGE--KGKSGKTGQPGLEGERGPPGS--RGERGQPGAT 847

Query: 510  GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLP 568
            G PG  G  G+DGA G  GE GLPG +GP G PG KG PG +G +G+ G  G +G+ G  
Sbjct: 848  GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907

Query: 569  GPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIR-GPKGVQGPRG 627
            G  GP G  G++GP G  G    GP G +G  G PG PG +G PGL  R G KG  GP G
Sbjct: 908  GQTGPPGPAGVLGPQGKTGEV--GPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPG 965

Query: 628  PVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV 683
            P+G  G  G    G PGP+G PG PGP GL+G     G  GA G PG RGP GP+G  G+
Sbjct: 966  PLGKEGPAG--LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023

Query: 684  ----GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGH-------GL 731
                G++GP G  G+KG  G  GPPG  G  GI G  GP G PG  G  G        G 
Sbjct: 1024 PGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGA 1083

Query: 732  PGQKGEHGERGDVGK------KGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEI 785
            PG KG  G++GD G       +G  G  G PG+ G QG +GP G  G   ++ ++    +
Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGV 1143

Query: 786  CG 787
             G
Sbjct: 1144 IG 1145



 Score =  431 bits (1109), Expect = e-120
 Identities = 269/601 (44%), Positives = 318/601 (52%), Gaps = 72/601 (11%)

Query: 241  ECEKGDPG---DPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296
            E E+G PG   + G PG  G PG KG+ G  G PG   +KG  G +GP G PG KG  G 
Sbjct: 829  EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            +G+ G+PG  G +G  G  G  GP G  G+ GP G  G  G  G +G PGPPGP G  G 
Sbjct: 889  QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948

Query: 357  PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414
            PG+ G++G KGE G  G  G  GP G+   G PGP+G  G PG  GL G+ G PGP G  
Sbjct: 949  PGLEGREGAKGELGPPGPLGKEGPAGLR--GFPGPKGGPGDPGPTGLKGDKGPPGPVGAN 1006

Query: 415  GSEGPTGPQG-LQGLSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQ 469
            GS G  GP G   G+ + G+ G  GPVGP G  G  G     G  G+ GI GP+GP GP 
Sbjct: 1007 GSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066

Query: 470  GPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
            G AG  G  G KG+VG  G  G +G  G    GP G+PG  G  G PG PG DGA G++G
Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDA--GPPGQPGIRGPAGHPGPPGADGAQGRRG 1124

Query: 529  EAGLPGARGPEG---------PPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPG 578
              GL G +G +G         PPG +G PGP G++G+ G  G+ G  G PGP GP+G  G
Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTG 1184

Query: 579  IMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGL----SIRGPKGVQGPRGPVGAPG 633
              G  G+PG    PG  G KG+RG  G PG  G PG+       G KG  GP G  G PG
Sbjct: 1185 SEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG 1244

Query: 634  LKG----DGYPGVPGPRGLPG---PPGPMGLRGV----------------GDTGAKGEPG 670
             KG    DG  G  GP GLPG   PPG  G+ G+                G  GA GEPG
Sbjct: 1245 KKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPG 1304

Query: 671  VRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG----YGSQGIKGEQGPQGF---PG 722
              GPPG  GP G +G +G +G+ G KG PGP GPPG     G++G  G  GP+G    PG
Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPG 1364

Query: 723  PKGTMGH-GLPGQKGEHGE---------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            P G  G  G PGQ G  G          +GD G KG+KG IG  G  G  G  G KGD G
Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424

Query: 773  L 773
            L
Sbjct: 1425 L 1425



 Score =  421 bits (1082), Expect = e-117
 Identities = 266/598 (44%), Positives = 312/598 (52%), Gaps = 88/598 (14%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G  G PGP G  G+PG+KGE G +G            +GP G+ G  G  G  G+ G+PG
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEG-----------PQGPRGLQGPHGPPGRVGKMGRPG 533

Query: 305  IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360
              G +G PG  GPKG RG  G+ G PG+ G +G  G+ G+PGPPG  G  GA G     G
Sbjct: 534  ADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG 593

Query: 361  QQGIKGERGQEGRPGAPGPIG----------------VGEPGQPGPRGPEGVPGERGLPG 404
            Q G  G RG  G  G+PGP G                VG PG+PGP G +G  G +GLPG
Sbjct: 594  QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653

Query: 405  -EGFPGPKGEK------------GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450
             +G  G  GEK            GS+GP G  G +G +  GEKG  GP G  GP G PG 
Sbjct: 654  PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT--GEKGAQGPPGSAGPPGYPGP 711

Query: 451  ---------IGSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGPRGPVG- 496
                      G QGE+G +G  G PG +G  G    QG PG+ G  G+ GP GP+G  G 
Sbjct: 712  RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771

Query: 497  IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGD 552
             G +GP G  G  G  G PG+PG  G  G KG  G PG  GP G  GK    GQPG +G+
Sbjct: 772  AGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE 831

Query: 553  EGKKGSKGNQGQRGLPGPEGPKGE------PGIMGPFGMPG----TSIPGPPGPKGDRGG 602
             G  GS+G +GQ G  G  GPKG+      PGI G  G+PG       PGP GP G +G 
Sbjct: 832  RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 603  PGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGDGYP-GVPGPRGLPGPPGPMGLRGV 660
             G PG  G+ G L  +G  G  GP G +G  G  G+  P G  GP G PGPPG  GL G+
Sbjct: 892  DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951

Query: 661  -GDTGAKGEPGVRGPPGPSGPRGV-GTQGPK---GDTGQKGLPGPPGPPG-YGSQGIKGE 714
             G  GAKGE G  GP G  GP G+ G  GPK   GD G  GL G  GPPG  G+ G  GE
Sbjct: 952  EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011

Query: 715  QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            +GP G  G     G GLPGQ G  G  G  GKKG +GE G PG  GK G+ GP G LG
Sbjct: 1012 RGPLGPAG-----GIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064



 Score =  403 bits (1036), Expect = e-112
 Identities = 275/659 (41%), Positives = 322/659 (48%), Gaps = 126/659 (19%)

Query: 232  EKKCERKICECEKGDP--GDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPG 289
            EK  + +    EKG    G PG PG  G  G  G  GP G P     G+ G  GP G+PG
Sbjct: 374  EKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFP-----GDPGPPGPAGLPG 428

Query: 290  YKGDKGERGE---------------------------------------CGKPGIKGDKG 310
              G  G RG                                         G PG  G  G
Sbjct: 429  IPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG 488

Query: 311  SPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI----GQQGIKG 366
             PGP G  G  G++G  G  G  GP+G QG  G PG  G  G PGA G     G  G KG
Sbjct: 489  RPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKG 548

Query: 367  ERGQEGRPGAPGPIG-------VGEPGQP---GPRGPEGVPGERGLPGEGFPGPK---GE 413
            +RG +G PG PG  G       VG+PG P   G RG EG PG  G  GE  PGP+   G 
Sbjct: 549  DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE--PGPRGLLGP 606

Query: 414  KGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGP 471
            +GS GPTG  G+ G+    G KG++GP G  GP G  G  GSQG  G QG IG PG +GP
Sbjct: 607  RGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666

Query: 472  AGQ----GLPGS------------KGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQ 514
             G     GLPGS             GE G  GP G  GP G  G +G KG  G+ GL G+
Sbjct: 667  PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGE 726

Query: 515  PGVPGEDGAAGKKGEAGL---------PGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQ 564
             G  GEDG  G KG+ GL         PG RG +GP G KGQ G  G+EG  GS G +G+
Sbjct: 727  KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGK 786

Query: 565  RGLPGPEGPKGEPGIMGPFGMPGTSIP----------GPPGPKGDRGGPGIPGFKGEPGL 614
             G+PG  G  G PG  G  G PG   P          G PG +G+RG PG  G +G+PG 
Sbjct: 787  LGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846

Query: 615  SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEP 669
            +  G  G +G  G  GAPG+ G+ G PG+ GP G PGP GP G +G     G  G +GE 
Sbjct: 847  T--GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL 904

Query: 670  GVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGEQGPQ 718
            G +G  GP GP GV    G  G  G  G++G PGPPGPPG        G +G KGE GP 
Sbjct: 905  GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPP 964

Query: 719  GFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK---GEIGEPGSPGKQGLQGPKGDLGL 773
            G  G +G  G  G PG KG  G+ G  G KGDK   G +G  GSPG++G  GP G +GL
Sbjct: 965  GPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023



 Score =  399 bits (1025), Expect = e-111
 Identities = 267/644 (41%), Positives = 314/644 (48%), Gaps = 135/644 (20%)

Query: 241 ECEKGDPGDPGPPGTHGN----------PGIKGERGPKGNPGNAQKGEAGERGPGGIPGY 290
           E E+GD    GP                PG  GE+G KG P   +KG+  E GP G PG 
Sbjct: 342 EDEEGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFE-GPPGAPGP 399

Query: 291 KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG--------------DPGPK 336
           +G  G  G  G PG  GD G PGP G  G  GI GI GPPG                 P 
Sbjct: 400 QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459

Query: 337 GFQ-------------GNKGEPGP------PGPYGSPGAPGI----GQQGIKGERGQEGR 373
            FQ               KG PGP      PGP G PG PG+    G +G +G RG +G 
Sbjct: 460 SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519

Query: 374 PGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE-------------GFPGP 410
            G PG +G           G PG  GP+G  G  G  GLPGE             G PG 
Sbjct: 520 HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGE 579

Query: 411 KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQ 469
            GE+G+EGP GP G  G    G +G +GP G  GP G PG+ G  G  G +G +GPPG  
Sbjct: 580 DGERGAEGPPGPTGQAG--EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEP 637

Query: 470 GPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE 529
           GP     PG +G  G  G  GP+G   IG  G KG PG+   PG PG+PG DG  G  G 
Sbjct: 638 GP-----PGQQGNHGSQGLPGPQGL--IGTPGEKGPPGN---PGIPGLPGSDGPLGHPGH 687

Query: 530 AGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG- 587
            G  G +G +GPPG  G PG  G  G KG+ GN+G +G  G +G  G PG  G  G+ G 
Sbjct: 688 EGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD 747

Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPR- 646
              PG PGP+G+ G  G  G  G+ G    GP G  G +G +G PGL   GYPG PGP+ 
Sbjct: 748 QGKPGAPGPRGEDGPEGPKGQAGQAG--EEGPPGSAGEKGKLGVPGL--PGYPGRPGPKG 803

Query: 647 --GLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPG 699
             G PGP GP+G +G  G TG  G  G RGPPG  G RG     G  GPKGD GQ G PG
Sbjct: 804 SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPG 863

Query: 700 PPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGE--------------- 737
            P     G +G+ G QGP GFPGPKG  GH       G PGQ+GE               
Sbjct: 864 IP-----GEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGV 918

Query: 738 ---HGERGDVGKKGDKGEIGEPGSPGKQGL------QGPKGDLG 772
               G+ G+VG  G++G  G PG PG+QGL      +G KG+LG
Sbjct: 919 LGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELG 962



 Score =  392 bits (1008), Expect = e-109
 Identities = 244/567 (43%), Positives = 285/567 (50%), Gaps = 115/567 (20%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG++G  G KG  G    G  G+ GP G+ G+ G KG  G+ G 
Sbjct: 933  ERGPPGPPGPPGEQGLPGLEGREGAKGELG--PPGPLGKEGPAGLRGFPGPKGGPGDPGP 990

Query: 303  PGIKGDKGSPGPYG------------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGP 350
             G+KGDKG PGP G            P G  G+ G +G  G  GP G +G++GE GPPGP
Sbjct: 991  TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 351  YGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGV 396
             G  G PG        G  G  GE G +G  GAPG  G        G PGQPG RGP G 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 397  PGERGLPG----EGFPGPKGEKGSEGPTG------PQGLQGL-SIKGEKGDIGPVGPQGP 445
            PG  G  G     G PG  G+KG +G  G      P GLQGL    GEKG++G VG  GP
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 446  MGIPG-------IGSQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQ 485
             G PG        GS+G  G+ G +G PG  G  G+             G+PG KG++G+
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230

Query: 486  MGPTGPRGPVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532
             G +GP G  G              G  GP G PG +G PG PGV G DG+ G+KG+   
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGD--- 1287

Query: 533  PGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SI 590
            PG  G  GPPG  G+PG  G  GK+G  G+ G+ G  G +G KGEPG  GP G  G    
Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGA 1347

Query: 591  PGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD------------ 637
             GPPG  G  G  GIPG  GEPGL    G  G  GP GP G PGLKGD            
Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407

Query: 638  ----------------GYPGV---PGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPS 678
                            G PGV   PGP+G PGPPGP     +G  G  G PGV GP G  
Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP-----IGSLGHPGPPGVAGPLGQK 1462

Query: 679  GPRGV-GTQGPKGDTGQKGLPGPPGPP 704
            G +G  G+ GP+GDTG  G PGPPG P
Sbjct: 1463 GSKGSPGSMGPRGDTGPAGPPGPPGAP 1489



 Score =  325 bits (834), Expect = 1e-88
 Identities = 207/442 (46%), Positives = 234/442 (52%), Gaps = 44/442 (9%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKG 292
            E+GD GD G PG  G+ G KG+ GP G PG              G  G RGP G+ G KG
Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133

Query: 293  DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQ---GNKGEPGPPG 349
            D G RG  G  G  G +G PGP G KG  G  G  GP G PGP+G Q   G++G PG PG
Sbjct: 1134 DDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG 1193

Query: 350  PYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE-- 405
              G PGA G  G++G  G+ G  G PG PGP G +GE G  GP G  G PG++G PGE  
Sbjct: 1194 GVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG 1253

Query: 406  --GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP 462
              G  GP G  G  GP G  G+ G+    GEKGD G VG  GP      G+ GE G  GP
Sbjct: 1254 AKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP-----GASGEPGAPGP 1308

Query: 463  IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGE 520
             G  GP G  G +G  G KG  G+ GP GP G  G +G +GP G  G  GL G PG  GE
Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368

Query: 521  DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580
             G  G  G+ G PG  GP      G PG KGD G KG KG+ G  GL GP G  GE G  
Sbjct: 1369 PGLLGAPGQMGPPGPLGP-----SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423

Query: 581  GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GY 639
               G+PG  + GPPGPKGD G PG  G  G P     GP GV GP G  G+ G  G  G 
Sbjct: 1424 ---GLPG--VQGPPGPKGDPGPPGPIGSLGHP-----GPPGVAGPLGQKGSKGSPGSMGP 1473

Query: 640  PGVPGPRGLPGPPG-PMGLRGV 660
             G  GP G PGPPG P  L G+
Sbjct: 1474 RGDTGPAGPPGPPGAPAELHGL 1495



 Score =  285 bits (729), Expect = 2e-76
 Identities = 185/422 (43%), Positives = 217/422 (51%), Gaps = 52/422 (12%)

Query: 389 GPRGPEGVPG--ERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPM 446
           G +G +G P   E+G   EG PG  G +G  GP+GP G  G       GD GP GP G  
Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFP-----GDPGPPGPAGLP 427

Query: 447 GIPGIGSQGEQGIQGPIGP-------------PGPQGPAGQGLPGSKGEVGQMGPTGPRG 493
           GIPGI      GI+GP G               GP     Q    +  +  Q+   GP G
Sbjct: 428 GIPGI-----DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPG 482

Query: 494 PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGD 552
           PVG+      G PG +GLPG PG+ GE+GA G +G  GL G  GP G  GK G+PG  G 
Sbjct: 483 PVGL-----TGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537

Query: 553 EGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEP 612
            G  G  G +G RG  G  G  GE G  G FG  G   PGPPG  G+RG  G PG  G+ 
Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ--PGPPGEDGERGAEGPPGPTGQA 595

Query: 613 GLSIRGPKGVQGPRG---PVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKG 667
           G    GP+G+ GPRG   P G PG+ G DG PG  G  G PG PGP G +G  G  G  G
Sbjct: 596 GEP--GPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653

Query: 668 EPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725
             G+ G PG  GP G  G  G  G  G  G PG  GP G  G+QG  G  GP G+PGP+G
Sbjct: 654 PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRG 713

Query: 726 TMG----HGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTK 775
             G     GL G+KGE GE      +GDVG KGD+G+ G PG  G+ G +GPKG  G   
Sbjct: 714 VKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAG 773

Query: 776 EE 777
           EE
Sbjct: 774 EE 775



 Score = 39.3 bits (90), Expect = 0.021
 Identities = 49/176 (27%), Positives = 61/176 (34%), Gaps = 43/176 (24%)

Query: 638 GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGV--RGPPGPSGPRGVGTQGPKGDTGQK 695
           G P  P PR      G    RG    G K    +    PP  S      T  PK +T   
Sbjct: 237 GEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAP 296

Query: 696 GLPGPPGP---------------------PGYGSQ--------GIKGEQGPQGFPG---- 722
            LP  P P                     P  G++          + E+G     G    
Sbjct: 297 NLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFR 356

Query: 723 ----PKGTMGHGLPGQKGEHGERGD--VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
               P  T     PG  GE G +G+  V +KG + E G PG+PG QG+ GP G  G
Sbjct: 357 AAEYPSRTQFQIFPG-AGEKGAKGEPAVIEKGQQFE-GPPGAPGPQGVVGPSGPPG 410


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  459 bits (1182), Expect = e-129
 Identities = 275/610 (45%), Positives = 318/610 (52%), Gaps = 95/610 (15%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            +G PG PG PG+ G PG  G +G  G PG       G  GP G PG  G  G +G  G P
Sbjct: 536  RGMPGSPGGPGSDGKPGPPGSQGESGRPG-----PPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQG 363
            G  G++G PG  GP+GP G  G TGP G PGP G  G+KG+ GPPGP G  G PG G   
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG--- 647

Query: 364  IKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP----------GEGFPGPKG 412
              G  G+ G+PG PGP G  G PG PG +G  G PGERG P          G G PGP+G
Sbjct: 648  --GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG 705

Query: 413  EKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIG 464
             KG+ GP GP G  G      + GE+G +G  GP+G  G PG     G  G+ G +GP G
Sbjct: 706  GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765

Query: 465  PPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPGV 517
            P GP GPAGQ  PG KGE G  G  G  GP G        G  GP G PG+ G  G+PG 
Sbjct: 766  PIGPPGPAGQ--PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG 823

Query: 518  PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGN------QGQRGLPGP 570
             GE GA G+KGE G PG  GP G  G  G PGP+G +G++GS G        G RGLPGP
Sbjct: 824  KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGP 883

Query: 571  EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPV 629
             G  G PG  GP G PG    GPPGP G+ G PG PG  G  G     G KG  G +GP 
Sbjct: 884  PGSNGNPGPPGPSGSPGKD--GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941

Query: 630  GAPGLKG----DGYPGVPGPRGLPGP---PGPMGLRG-VGDTGAKGEPGVRGPPGPSGPR 681
            GAPG  G     G  G+ GP G+PGP   PGP G++G  G  GA G  G RGPPGP G  
Sbjct: 942  GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP 1001

Query: 682  GV----------------------GTQGPKGDTGQKGLPGPPGPPGY------------- 706
            G+                      G+ G KGD G+ G PG PG PG+             
Sbjct: 1002 GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS 1061

Query: 707  GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
            G +G  G  GP G PGP G+ G     G  G KGE GERG  G KG +G  G PG+PG  
Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP 1121

Query: 763  GLQGPKGDLG 772
            G  G +G +G
Sbjct: 1122 GPAGQQGAIG 1131



 Score =  446 bits (1147), Expect = e-125
 Identities = 280/648 (43%), Positives = 315/648 (48%), Gaps = 122/648 (18%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            G  G PGP G +G PG++G  G  G  G   + G  GERG  GIPG  G KGE G+ G P
Sbjct: 411  GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS---------P 354
            G  G  G PG  G +G  G +G  GP G PG KG  G +G PGP GP G+         P
Sbjct: 471  GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530

Query: 355  GAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP--------- 403
            G PG+ G  G  G  G +G+PG PG  G  G PG PGP GP G PG  G P         
Sbjct: 531  GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590

Query: 404  -------GEGFPGPKGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQG 455
                   G G PGP+G  G  G TGPQG  G     G+KGD GP GPQG  G+PG G  G
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG--G 648

Query: 456  EQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI----------------G 498
              G  G  G PGP+G AG  G PG KG+ G  G  GP G  G                 G
Sbjct: 649  PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 499  VQGPKGEPGSIGLPGQPGVPGED---GAAGKKGEAGLPGARGPEGPPGKGQP-------G 548
              GP G PG+ G PG  G+PGE    G+ G KG+ G PG  G +G PGK  P       G
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 549  PKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGP---G 604
            P G  G+ G KG  G  GLPG  GP+G PG  G  G PG    PG PG  G+ GG    G
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 605  IPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD----------------GYPGVPGPRG 647
             PG KGE G   + GP G  GP GP G  G+KG+                G PG PG  G
Sbjct: 829  APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG 888

Query: 648  LPGPPGPMGLRG-------VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGD----- 691
             PGPPGP G  G        G+TGA G PGV GP G +G  G     G QGP G      
Sbjct: 889  NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG 948

Query: 692  ----TGQKGLPGPPGPPG----YGSQGIKGEQ---------------GPQGFPGPKGTMG 728
                TG +GL GPPG PG     G QG+KGE                GPQG PG  GT G
Sbjct: 949  IAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008

Query: 729  H----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
                 G PG  G  G  G  G KGD+GE G PG+PG  G  GP G +G
Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056



 Score =  444 bits (1141), Expect = e-124
 Identities = 276/631 (43%), Positives = 324/631 (51%), Gaps = 105/631 (16%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKP 303
           G PG PGPPGT G+PG  G  G +G PG   Q G +G  GP G  G  G  G+ GE G+P
Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236

Query: 304 GIKGDKGSPGPYGPKGPRGIQGI------------------TGPPGDPGPKGFQGNKGEP 345
           G  G++G PGP G KGP GI G                   TG PG  G  G  G  G P
Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296

Query: 346 GPPGPYGSP---GAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPE 394
           GP GP G+P   G PG+    G +G  G RG +G+PG PGP G     G PG  G  GP 
Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356

Query: 395 GVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDI------------GPV 440
           G PG  G PG+ G PGP+G  G++GP GP G+ G    KGE G              GP 
Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416

Query: 441 GPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ----GLPGSKGEVGQMGPTGPRGPV 495
           GP G  G PG+ G  GE G  G  G PGP+G  G+    G+PG+KGE G+ G  G  G  
Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN 476

Query: 496 GI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK---------- 544
           G+ G  G +G PG  G  G  G+PGE G AG++G  G  G RG  G PG+          
Sbjct: 477 GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR 536

Query: 545 ---GQPGPKGDEGKKGSKGNQGQRGL---PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598
              G PG  G +GK G  G+QG+ G    PGP GP+G+PG+MG  G  G    G PG  G
Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND--GAPGKNG 594

Query: 599 DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD----------GYPGV---PGP 645
           +RGGPG PG +G PG +  G  G QGP GP G  G KGD          G PG    PG 
Sbjct: 595 ERGGPGGPGPQGPPGKN--GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE 652

Query: 646 RGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGP 700
            G PG PGP G  G     G  G  G PG RGPPG +G  G+ G  GP G  G KG  GP
Sbjct: 653 NGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP 712

Query: 701 PGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERGDV----- 744
           PGPPG     G QG+ GE+G  G PGPKG  G        G+PG+ G  G  G +     
Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772

Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            G+ GDKGE G PG PG  G +G  G+ G T
Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSPGERGET 803



 Score =  443 bits (1140), Expect = e-124
 Identities = 274/613 (44%), Positives = 314/613 (51%), Gaps = 90/613 (14%)

Query: 245 GDPGDPGPPGTHG---NPGIKGERGPKGNPGN----AQKGE------AGERGPGGIPGYK 291
           G PG PGPPGT G   +PG KGE GP G+PG+     Q+GE      AG +GP G PG  
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389

Query: 292 GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
           G  G +GE G  GI G  G  G  GP GP G  G  G  G  G  G  G KGEPGP G  
Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449

Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPG 404
           G  G PG+   G KGE G++G PG PG  G+       G PG  GP GP G+PGE+G  G
Sbjct: 450 GEAGIPGV--PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507

Query: 405 E-GFPGPKGEKGSEGPTGPQGLQG----------------------LSIKGEKGDIGPVG 441
           E G PGP G +G+ G  G  G+ G                         +GE G  GP G
Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG 567

Query: 442 PQGPMGIPGI----------GSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVG 484
           P GP G PG+          G+ G+ G +G  G PGPQGP G       QG PG  G  G
Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627

Query: 485 QMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543
             G TGP GP G+ G+ G  G PG  G PG+PG  G+ GA G  G  G  GA G  GPPG
Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPG 687

Query: 544 -KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG 602
             G PG +G  G  G +G +G  G PGP G  G PG+ G  G  G    G PGPKGD+G 
Sbjct: 688 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL--GSPGPKGDKGE 745

Query: 603 PGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGLKGDG----YPGVPGPRGLPG------P 651
           PG PG  G PG    RGP G  GP GP G PG KG+G     PG+ GPRG PG      P
Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP 805

Query: 652 PGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGI 711
           PGP G  G    G  GEPG +G  G  G +G G  GP G  G  G  GP GPPG   QG+
Sbjct: 806 PGPAGFPGA--PGQNGEPGGKGERGAPGEKGEG--GPPGVAGPPGGSGPAGPPG--PQGV 859

Query: 712 KGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPG------SPGKQGL 764
           KGE+G  G PG  G  G  GLPG  G +G  G  G  G  G+ G PG      +PG  G+
Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919

Query: 765 QGPKGDLGLTKEE 777
            GPKGD G   E+
Sbjct: 920 SGPKGDAGQPGEK 932



 Score =  436 bits (1122), Expect = e-122
 Identities = 266/578 (46%), Positives = 300/578 (51%), Gaps = 62/578 (10%)

Query: 243 EKGDPGDPGP---PGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERG 298
           E G PG  GP   PG  G PG+ G  G +GN G     G+ G  GP G  G+ G  G +G
Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351

Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
           E G  G  G  G+PG  G  GP+G  G  GPPG PG  G  G KGE GP    G PGAPG
Sbjct: 352 EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA---GIPGAPG 408

Query: 359 I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416
           + G +G  G  G  G PG  G  G GEPG+ G +G  G  GERG  G  G PG KGE G 
Sbjct: 409 LMGARGPPGPAGANGAPGLRG--GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGK 466

Query: 417 EGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPG------- 467
           +G  G  G  GL    GE+G  G  GP GP GIPG  G  GE+G  GP GP G       
Sbjct: 467 DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526

Query: 468 ---PQGPAGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGE 520
              P GP  +G+PGS G  G  G  GP G  G     G  GP G  G  G+ G PG  G 
Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGN 586

Query: 521 DGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
           DGA GK GE G PG  GP+GPPGK G+ GP+G  G  G  G++G  G PGP+G +G PG 
Sbjct: 587 DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646

Query: 580 MGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-G 638
            GP G  G   PG PGPKGD G PG PG KG+      G  G +GP G  GAPGL+G  G
Sbjct: 647 GGPPGENGK--PGEPGPKGDAGAPGAPGGKGD-----AGAPGERGPPGLAGAPGLRGGAG 699

Query: 639 YPGVPGPRGLPGPPGPMGLRGV-------------------GDTGAKGEPGVRGPPGPSG 679
            PG  G +G  GPPGP G  G                    GD G  G PG  G PG  G
Sbjct: 700 PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759

Query: 680 PRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQ 734
           PRG    +G  GP G  G KG  G PG PG  G +G  GE+G  G PGP G    G PGQ
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF--PGAPGQ 817

Query: 735 KGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            GE G +G+ G  G+KGE G PG  G  G  GP G  G
Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPG 855



 Score =  431 bits (1107), Expect = e-120
 Identities = 278/661 (42%), Positives = 314/661 (47%), Gaps = 134/661 (20%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP------------------G 285
           KGDPG PG PG +G+PGI G+ G  G+PG     E+   GP                  G
Sbjct: 108 KGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVG 167

Query: 286 GIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF------- 338
           G+ GY G  G  G  G PG  G  GSPG  G +GP G  G  GP G PGP G        
Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227

Query: 339 --QGNKGEPGPPGPYGSPGAPGI-------------GQQGIKGERGQEGRPGAPGPIG-- 381
              G  G PG PG  G PG PGI             G +G  G  G++G  GAPG  G  
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 382 --VGEPGQPGPRGPEGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQGL-SIK 431
              GE G PGP GP G PGERG PG        G  G +G  G  GP GP G  G     
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347

Query: 432 GEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSK 480
           G KG++GP G  G  G PG     G QG  G QGP GPPG  G  G        G+PG+ 
Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407

Query: 481 GEVGQMGPTGPRGPVGI----------------GVQGPKGEPGSIGLPGQPGVPGEDGAA 524
           G +G  GP GP G  G                 G  GP+GE G  G+PG PG  GEDG  
Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467

Query: 525 GKKGEA---GLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMG 581
           G  GE    GLPGA G  G P  G  GP G  G  G KG  G+RG PGP GP+G  G  G
Sbjct: 468 GSPGEPGANGLPGAAGERGAP--GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525

Query: 582 PFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGP---VGAPGL 634
             G+PG      +PG PG  G  G PG PG +GE G    GP G  GPRG    +G PG 
Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP--GPPGPSGPRGQPGVMGFPGP 583

Query: 635 KG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGP------PGPSGPRGV--- 683
           KG DG PG  G RG PG PGP G  G  G+TG +G PG  GP       GP GP+G+   
Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL 643

Query: 684 -GTQGPKGDTGQKGLPGPPG-------PPGYGSQGIKGEQGPQGF------------PGP 723
            GT GP G+ G+ G PGP G       P G G  G  GE+GP G             PGP
Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703

Query: 724 KGTMG----------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
           +G  G           G PG +G  GERG +G  G KG+ GEPG PG  G+ G  G  G 
Sbjct: 704 EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGP 763

Query: 774 T 774
           T
Sbjct: 764 T 764



 Score =  417 bits (1071), Expect = e-116
 Identities = 264/598 (44%), Positives = 308/598 (51%), Gaps = 84/598 (14%)

Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGI--------PGYKGDKGER 297
           P   GP G  G+PG  G  G  G+PG   Q G  G  GP GI          Y       
Sbjct: 99  PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSY 158

Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
                  + G  G PGP GP GP G  G +G PG PG  G+QG  GEPG  GP G PG P
Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218

Query: 358 G-IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKG 415
           G IG  G  G+ G+ GRPG PG  G+  PG PG +GP G+PG  G+ G  GF G  GEKG
Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGL--PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276

Query: 416 SEGPTGPQGLQGLSIKGEKGDIGPVGPQGP------MGIPGI----GSQGEQGIQGPIGP 465
             G  G +G  GL   GE G  GP+GP+G        G+PG     G+ G +G  G  GP
Sbjct: 277 ETGAPGLKGENGL--PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGP 334

Query: 466 PGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGA 523
           PGP G AG  G PG+KGEVG  G  G  G  G  G  GP+G  G+ G PG PG+ G  G 
Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394

Query: 524 AGKKGEAGLP------GARGPEGPP----------GKGQPGPKGDEGKKGSKGNQGQRGL 567
            G+ G AG+P      GARGP GP           G G+PG  G +G+ G +G +G+ G+
Sbjct: 395 KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454

Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGP---------GIPGFKGEPGLSIRG 618
           PG  G KGE G  G  G PG +  G PG  G+RG P         GIPG KG  G   RG
Sbjct: 455 PGVPGAKGEDGKDGSPGEPGAN--GLPGAAGERGAPGFRGPAGPNGIPGEKGPAG--ERG 510

Query: 619 PKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGP 677
             G  GPRG  G PG   DG PG PG RG+PG PG  G  G  G  G++GE G  GPPGP
Sbjct: 511 APGPAGPRGAAGEPG--RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568

Query: 678 SGPRG----VGTQGPKGD------TGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTM 727
           SGPRG    +G  GPKG+       G++G PG PGP   G  G  GE GPQG PGP G  
Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP--QGPPGKNGETGPQGPPGPTGPG 626

Query: 728 G-------------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           G              GLPG  G  GE G  G+ G KG+ G PG+PG +G  G  G+ G
Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERG 684



 Score =  324 bits (830), Expect = 3e-88
 Identities = 220/552 (39%), Positives = 252/552 (45%), Gaps = 139/552 (25%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP---GGIPGYKGDKGERGE 299
            + G PG+ GPPG  G PG++G  GP G  G   KG AG  GP    G PG +G  GERG 
Sbjct: 676  DAGAPGERGPPGLAGAPGLRGGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGG 733

Query: 300  CGKPGIKGDKGSPG------------PYGPKGPRGIQGITGPPGDPG------------P 335
             G PG KGDKG PG            P GP GP G  G  G PGD G            P
Sbjct: 734  LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP 793

Query: 336  KGFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEP----GQPGP 390
            +G  G +GE GPPGP G PGAPG  G+ G KGERG  G  G  GP GV  P    G  GP
Sbjct: 794  RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853

Query: 391  RGPEGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLS----------- 429
             GP+GV GERG PG           G PGP G  G+ GP GP G  G             
Sbjct: 854  PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913

Query: 430  -----IKGEKGDIG------------PVGPQGPMGIPGI----GSQGEQGIQGPIGPPGP 468
                 + G KGD G            P G  GP+GI GI    G  G  G+ GP G PGP
Sbjct: 914  PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973

Query: 469  QGPAGQ-GLPGSKGEVGQMGPTGPRG----------------------------PVGIGV 499
            QG  G+ G PG+ G  G+ GP GP+G                            P G G 
Sbjct: 974  QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033

Query: 500  QGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGP------ 549
            +G  G PG+ G PG PG PG  G AGK G+ G  G  GP G PG    +G PGP      
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093

Query: 550  KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGF 608
            KG+ G++G+ G +G RG PG  G  G PG  G  G  G+  P GP GP G  G PG  G 
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153

Query: 609  KGEPG-LSIRGPKGVQGPRG------------PVGAPGLKGDGYPGVPGPRGLPGPPGPM 655
             G PG +   GP+G +G RG            P G P        G PGP    G  G  
Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP--------GAPGP--CCGGVGAA 1203

Query: 656  GLRGVGDTGAKG 667
             + G+G   A G
Sbjct: 1204 AIAGIGGEKAGG 1215



 Score =  303 bits (777), Expect = 5e-82
 Identities = 184/434 (42%), Positives = 219/434 (50%), Gaps = 72/434 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G+ G PGP G  G PG  GE G KG  G    GE GE GP G+ G  G  G  G  G 
Sbjct: 799  ERGETGPPGPAGFPGAPGQNGEPGGKGERG--APGEKGEGGPPGVAGPPGGSGPAGPPGP 856

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPG---DPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
             G+KG++GSPG  G  G  G +G+ GPPG   +PGP G  G+ G+ GPPGP G+ GAPG 
Sbjct: 857  QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS 916

Query: 359  ---------IGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGL 402
                      GQ G KG  G +G PGAPGP+G+       G  G PG  GP G PG +G+
Sbjct: 917  PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 403  PGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI---------- 451
             GE G PG  G  G  GP GPQGL GL+  G  G+ G  G  G  G+PG           
Sbjct: 977  KGESGKPGANGLSGERGPPGPQGLPGLA--GTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034

Query: 452  ---GSQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPV 495
               GS G  G  G  GPPGP GPAG+             G PG  G  G  GP GPRG  
Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094

Query: 496  G-------IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK---- 544
            G        G++G +G PG+ G PG PG  G+ GA G  G AG  G  GP GPPGK    
Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTS 1154

Query: 545  ------GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598
                  G PGP+G+ G++GS+G+ G  G PGP GP G PG        G       G  G
Sbjct: 1155 GHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC----CGGVGAAAIAGIGG 1210

Query: 599  DRGGPGIPGFKGEP 612
            ++ G   P +  EP
Sbjct: 1211 EKAGGFAPYYGDEP 1224



 Score =  155 bits (393), Expect = 2e-37
 Identities = 101/243 (41%), Positives = 114/243 (46%), Gaps = 34/243 (13%)

Query: 538 PEGPP-GKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGP 596
           P  PP G+G  GPKGD G  G  G  G  G+PG  G  G PG       PG     P GP
Sbjct: 95  PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG------PPGICESCPTGP 148

Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPM 655
           +     P    +  + G+++ G  G  GP GP G PG  G  G+PG PG  G  GPPG  
Sbjct: 149 QNY--SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG-- 204

Query: 656 GLRGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKG 713
                       EPG  GP GP GP G +G  GP G  G+ G PG PG  G  G  GIKG
Sbjct: 205 ------------EPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252

Query: 714 EQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
             G  GFPG KG    G  G+ GE GE G  G KG      E G PG+ G  GP G  G 
Sbjct: 253 PAGIPGFPGMKGH--RGFDGRNGEKGETGAPGLKG------ENGLPGENGAPGPMGPRGA 304

Query: 774 TKE 776
             E
Sbjct: 305 PGE 307



 Score =  147 bits (372), Expect = 4e-35
 Identities = 91/208 (43%), Positives = 105/208 (50%), Gaps = 19/208 (9%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            ++G+ G PG PG  G+PG  G  GP G  G+  +GE+G  GP G PG  G +G  G  G 
Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKSGD--RGESGPAGPAGAPGPAGSRGAPGPQGP 1090

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362
             G KG+ G  G  G KG RG  G  G PG PGP G QG  G PGP GP G  G       
Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP------ 1144

Query: 363  GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGP-T 420
               G  G++G  G PGPI     G PGPRG  G  G  G PG  G PGP G  G+ GP  
Sbjct: 1145 --SGPPGKDGTSGHPGPI-----GPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCC 1197

Query: 421  GPQGLQGLS-IKGEK-GDIGPVGPQGPM 446
            G  G   ++ I GEK G   P     PM
Sbjct: 1198 GGVGAAAIAGIGGEKAGGFAPYYGDEPM 1225



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 21/54 (38%), Positives = 22/54 (40%), Gaps = 5/54 (9%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDK 294
            E   G PG PGPPG  G PG        G  G A     G    GG   Y GD+
Sbjct: 1175 EGSPGHPGQPGPPGPPGAPG-----PCCGGVGAAAIAGIGGEKAGGFAPYYGDE 1223


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  452 bits (1162), Expect = e-126
 Identities = 309/783 (39%), Positives = 378/783 (48%), Gaps = 133/783 (16%)

Query: 107  PFSSWKDLQTFKQKVKSMNLIG-QGTFSYYAISNATRLL---KREGRKDGVKVVLLMTDG 162
            P +   DL    Q+++ M  +   G     A+  A R +      GR+  V  V+++   
Sbjct: 1107 PLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLL-- 1164

Query: 163  IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDK 222
            +D P   D+ S   +A+ SG++ + + ++    E   RL  G  S +    + D   +D+
Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224

Query: 223  IQDRL-----DILFEKKCERKICE--CEKGDPGDPG---------PPGTHGNPGIKGERG 266
                L        F  +   + C   C KG  G+PG         PPG  G PG  G  G
Sbjct: 1225 AVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPG 1284

Query: 267  PKGNPGNAQ-KGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQG 325
            P+G PG+A  KGE G  G  G PG  G  G  G  G PG+KG  G PGP G  G RG +G
Sbjct: 1285 PQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRG 1344

Query: 326  ITGPPGDPGP------KGFQGNKGEPGP------------PGPYGSPGAPGIGQQGIKGE 367
              G PG PG        G  G KG+PGP            PGP G PG PG   +G KG+
Sbjct: 1345 PKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGD 1404

Query: 368  RGQEGRPG------APGPIGV-GEPGQPGPRGPEGVPGERGLPGE------GFPGPKGEK 414
            RG+ G PG      APG  G+ G PG PGP+GP G PG++G  G+      G PG  G  
Sbjct: 1405 RGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP 1464

Query: 415  GSEGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIG 464
            G +GP GP G  G          L   GEKG+ GP GP G  G+PG+   G  G +GP G
Sbjct: 1465 GEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVA--GRPGAKGPEG 1522

Query: 465  PPGPQGPAGQ----GLPGS-----------KGEVGQMGPTGPRGPVGI------------ 497
            PPGP G  G+    G PG            KGE G +GP GPRG  G+            
Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLP 1582

Query: 498  GVQGPKGEPGS---IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQP 547
            G  GPKG+PG    IGL G+ G PG+ G  G+KG+ G PG  GP GP G       KG  
Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642

Query: 548  GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-IPGPPGPKGDRGGPGIP 606
            GP GD G  G  G +G RG PG  GP GE G  G  G  G +  PG  GPKGDRG PG P
Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702

Query: 607  GFKGE-----PGLSIRGP---KGVQGPRGPVGAPGLKGDGYPGVPGPRGLPG---PPGPM 655
            G  G      PG   +G    +G +GPRGP G PGL     PG PG RG+ G   PPGP 
Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGL-----PGAPGERGIEGFRGPPGPQ 1757

Query: 656  GLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGE 714
            G  GV   G  GE G RGPPG  G  G+ G  G  G +G  G  G  G PG    G+ G 
Sbjct: 1758 GDPGV--RGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG--RDGLPGL 1813

Query: 715  QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            +G QG PGP G  G  LPG+ GE G      K G  G+ GEPG PG+ G +G KGD G +
Sbjct: 1814 RGEQGLPGPSGPPG--LPGKPGEDG------KPGLNGKNGEPGDPGEDGRKGEKGDSGAS 1865

Query: 775  KEE 777
              E
Sbjct: 1866 GRE 1868



 Score =  426 bits (1095), Expect = e-119
 Identities = 270/625 (43%), Positives = 327/625 (52%), Gaps = 101/625 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGI------PGYKGDKGE 296
            E+G+ G  GPPG  G PG  G  GPK +      G +GE+GP G+      PG  GD+G 
Sbjct: 2068 ERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGP 2127

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            +G+ G PGIKGD+G PGP G  G  G+ G  G  G  G  G QG +G PGP G +G PG 
Sbjct: 2128 KGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGP 2187

Query: 357  PGI----------GQQGIKGERGQEGRP--GAPGPIG-VGEPGQPGPRGPEGVPGERGLP 403
            PG           G  G+KGE G+ G P  G  GP G VG PG PGP G  G  G  GLP
Sbjct: 2188 PGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLP 2247

Query: 404  GE----GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG------IG 452
            G+    G PG  G  G+ G  G +G  G+    G  G +GP G  GP G PG       G
Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307

Query: 453  SQGEQGIQGP-----IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPK 503
            ++GE+G  G      +G PG +G   +GLPG +GE G+ G  G  G  G     G  GPK
Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKG--DRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK 2365

Query: 504  GEPG--SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKG 557
            G  G   +G+PG PG PG  G  G  G  GLPGA G  G PG    +G+ G  G  G++G
Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERG 2425

Query: 558  SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP------GPPGPKGDRGGPGIPGFKGE 611
              G  G+ G+PGP GP G PG +GP G  G          G PGP+G+RG PGI G  G 
Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR 2485

Query: 612  PGLSIRGPKGVQGP---------RGPVGAPGLKGD-----------------GYPGVPGP 645
            PG    GP+G+ GP         +G VG+ GLKGD                 G  G  GP
Sbjct: 2486 PGQ--EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543

Query: 646  RGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPP 704
            RGL G  GP G  G  GD G+KGEPG +G  G  G RG+   GP+G  G  G+PG PG P
Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL--LGPQGQPGAAGIPGDPGSP 2601

Query: 705  GY-GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERGDVGK---KGDKGEI 753
            G  G  GI+GE+G  GF GP+G  G        GL G+KG+ GE G  G+    G KGE+
Sbjct: 2602 GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEM 2661

Query: 754  GEP------GSPGKQGLQGPKGDLG 772
            GEP      G+PGK+GL GPKGD G
Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRG 2686



 Score =  415 bits (1067), Expect = e-115
 Identities = 293/734 (39%), Positives = 345/734 (47%), Gaps = 204/734 (27%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300
            G  GD G PG  G  G KGERGP G  G+       G  G +GP G PG  G +GE+GE 
Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536

Query: 301  GKPGI-----------KGDKGSPGPYGPKGPRGIQGITGPPG-----DPGPKGFQGNKG- 343
            G+PG            KG+KG  GP GP+G  G+QG  GPPG     DPGPKG  G++G 
Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596

Query: 344  -----------EPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV--- 382
                       + GPPG  G PG PG        G+ G  GE+G EG PG PG  G    
Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656

Query: 383  -GEPGQPGPRGPEGVPGERGLPGE-------GFPGPKGEKGSEGPTGPQGL-----QGLS 429
             G  G PG RGP G  G++G PGE       G  GPKG++G  GP GP G       G  
Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716

Query: 430  IKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGP 488
             KGE GD G  GP+GP G PG+ G+ GE+GI+G  GPPGPQG  G  + G  GE G  GP
Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG--VRGPAGEKGDRGP 1774

Query: 489  TGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK--- 544
             G  G  G+ G  G  G  G  G  G+ G PG DG  G +GE GLPG  GP G PGK   
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 545  ----------GQPGPKGDEGKKGSKGN------------QGQRGLPGPEGPKGEPGIMGP 582
                      G+PG  G++G+KG KG+            +G+RG PG  GP+G PG+ GP
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 583  FGMPGTSIPGPPG---PKGDRGG---------PGIPGFKGEPG----------------- 613
             G PG   PG PG   PKGDRG          PG  G +GEPG                 
Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKAS 1954

Query: 614  ----------------LSI----RGPKG---VQGP---RGPVGAPG---LKGD-GYPGVP 643
                            L +    RGPKG    QGP    GP+G PG   LKGD G PG  
Sbjct: 1955 ALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ 2014

Query: 644  GPRGLP----GPPGPMGLRG----------------VGDTGAKGE--------------- 668
            GP GL     GPPGP GL G                VG+ G  GE               
Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074

Query: 669  ------PGVRGPPGPSGPR------GVGTQGPKGDTGQKGLPGPPGPPG----YGSQGIK 712
                  PG  GPPGP GP+      G G  G +G  G KG  G PG  G     G +G+ 
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134

Query: 713  GEQGPQGFPGPKGTMGH-GLPGQKGE---------HGERGDVGKKGDKGEIGEPGSPGKQ 762
            G +G +G PGP+G  G+ GLPG++G           G RG  G  G  G+ G PG+PG  
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194

Query: 763  GLQGPKGDLGLTKE 776
            G  GP+G  GL  E
Sbjct: 2195 GPAGPQGPSGLKGE 2208



 Score =  413 bits (1061), Expect = e-115
 Identities = 294/749 (39%), Positives = 339/749 (45%), Gaps = 226/749 (30%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPK--------GNPGNAQKGEAGERGPGGIPGYKGDKGE 296
            G PG PGP G  G PG KGE+G          G PG+   GE G RGP G  G KGD+G 
Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP--GEQGPRGPPGAIGPKGDRGF 1484

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGI---QGITGPPGDPGPKGFQGNKGEPGPP----- 348
             G  G+ G KG++G PGP G +G  G+    G  GP G PGP G QG KGEPG P     
Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544

Query: 349  ---------------GPYGSPGAPGI---------------------------------- 359
                           GP G  GA G+                                  
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604

Query: 360  --GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVP---GERGL----- 402
              G  G  GE+G  GRPG PGP+G       VGE G  GP G  G+P   GERGL     
Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664

Query: 403  -------------PGE-------GFPGPKGEKGSEGPTGPQGL-----QGLSIKGEKGDI 437
                         PGE       G  GPKG++G  GP GP G       G   KGE GD 
Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDR 1724

Query: 438  GPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG 496
            G  GP+GP G PG+ G+ GE+GI+G  GPPGPQG    G+ G  GE G  GP G  G  G
Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG--DPGVRGPAGEKGDRGPPGLDGRSG 1782

Query: 497  I-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----------- 544
            + G  G  G  G  G  G+ G PG DG  G +GE GLPG  GP G PGK           
Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842

Query: 545  --GQPGPKGDEGKKGSKGN------------QGQRGLPGPEGPKGEPGIMGPFGMPGTSI 590
              G+PG  G++G+KG KG+            +G+RG PG  GP+G PG+ GP G PG   
Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902

Query: 591  PGPP---GPKGDRGG---------PGIPGFKGEPG------------------------- 613
            PG P   GPKGDRG          PG  G +GEPG                         
Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962

Query: 614  --------LSI----RGPK---GVQGP---RGPVGAP---GLKGD-GYPGVPGPRGLP-- 649
                    L +    RGPK   G QGP    GP+G P   GLKGD G PG  GP GL   
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALG 2022

Query: 650  --GPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
              GPPGP GL G              G  G  G PG RG  G  G R  G QG  G  G 
Sbjct: 2023 ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGER--GEQGRDGPPGL 2080

Query: 695  KGLPGPPGPPG------YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV 744
             G PGPPGPPG          G+ GEQGP G  G KG  G     G  G +G  G +GD 
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDR 2140

Query: 745  GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G+ G +G+ G PG PG++G+ GP+G  GL
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169



 Score =  412 bits (1059), Expect = e-115
 Identities = 288/682 (42%), Positives = 332/682 (48%), Gaps = 158/682 (23%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGN--PGN-AQKGEAGERGPGGIPGYKGDKGERGEC 300
            KG+ GD GP G  G  G++GERGP G   PG+   KG+ G+RGP G+ G  G  G+ G  
Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP- 1611

Query: 301  GKPGIKGDKGSPGPYGPKGPR------GIQGITGPPGDP------GPKGFQGNKGEPGPP 348
              PG KGD G PGP GP GPR      G +G  GPPGDP      G +G +G  G  GP 
Sbjct: 1612 --PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV 1669

Query: 349  GPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-----------VGEP---GQPGP 390
            G  G  G PG     G  G  G +G  G PG PGP G            GEP   GQ GP
Sbjct: 1670 GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGP 1729

Query: 391  RGPEGVPGERGLPGE-------GFPGPKGEKGSEGPT------GPQGLQGLS-IKGEKGD 436
            RGP+G PG  G PGE       G PGP+G+ G  GP       GP GL G S + G+ G 
Sbjct: 1730 RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789

Query: 437  IGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQGPAGQ----------GLPGS 479
             GP GP G  G  G        G +GEQG+ GP GPPG  G  G+          G PG 
Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGD 1849

Query: 480  KGEVGQM---------------GPTGPRGPVGI-GVQGPKGEPGSIGLPGQ--PGVP--- 518
             GE G+                GP G RG  GI G QGP G PG +G PGQ  PGVP   
Sbjct: 1850 PGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGT 1909

Query: 519  ---GEDGAAGKKGEAGLPGARGPEGPPG-------------------------------- 543
               G+ G  G KGE GLPG RG  G PG                                
Sbjct: 1910 GPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGS 1969

Query: 544  -----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSI--PGPPGP 596
                 + + GPKGD G++G  G +G  G PG  G KG+ G  GP G PG ++   GPPGP
Sbjct: 1970 FLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGP 2029

Query: 597  KGDRGGPGIPGFKGEP----GLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGP 651
             G  G PG PG  G P    G+   G  G +G RG  G  G +G DG PG+PG  G PGP
Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP 2089

Query: 652  PGPM--------GLRG----VGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLP 698
            PGP         GL G     G  GAKGEPG  G  GP G RGV G +G +G+ G +G  
Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149

Query: 699  GPPGPPG----YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGD---KG 751
            G PG PG     G +G  G QGP+G PGP G  GHG PG  G  G  G  G +G    KG
Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVG--GHGDPGPPGAPGLAGPAGPQGPSGLKG 2207

Query: 752  EIGEPGSPGKQGLQGPKGDLGL 773
            E GE G PG+ GL GP G +GL
Sbjct: 2208 EPGETGPPGR-GLTGPTGAVGL 2228



 Score =  410 bits (1054), Expect = e-114
 Identities = 260/636 (40%), Positives = 313/636 (49%), Gaps = 129/636 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG----NAQKGEAGERGPGGIPGYKGDKGERGEC 300
            G+ G PG  G  G PG  G++GPKG+ G       +GE G RG  G PG  G++G  G  
Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE 2164

Query: 301  GKPGIKGDKGSPGP---YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-------- 349
            GKPG++G +G PGP   +G  GP G  G+ GP G  GP G +G  GE GPPG        
Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224

Query: 350  ---------------PYGSPGAPG----------------IGQQGIKGERGQEGRPGAPG 378
                           P GSPG PG                 G+ G +G  G  G PG PG
Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284

Query: 379  PIG-----------------------------------VGEPGQ------PGPRGPEGVP 397
            P+G                                   VGEPG       PGPRG +G  
Sbjct: 2285 PVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEA 2344

Query: 398  GERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG------- 450
            G  G PG+  PG  G+KG+ GP G +G  G+ + G  G  GP G +G +G+PG       
Sbjct: 2345 GRAGEPGD--PGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402

Query: 451  IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGE 505
            +G  G+ G +G +G PGP G  G  G PG +G  G +GP GP G VG     G++G KG+
Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 506  PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQ 564
            PG +GLPG  G  GE G  G+ G  G  G RG  GPPG +G+ G KGD G  G KG++G 
Sbjct: 2463 PG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGD 2521

Query: 565  R----GLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620
                 G PGP G KG+ G  GP G+ G       GP+GD G PG  G KGEP        
Sbjct: 2522 SAVILGPPGPRGAKGDMGERGPRGLDGDK-----GPRGDNGDPGDKGSKGEP-------- 2568

Query: 621  GVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPS 678
               G +G  G PGL+G  G  G PG  G+PG PG  G  GV G  G KG+ G  GP G  
Sbjct: 2569 ---GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625

Query: 679  GPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKG 736
            G RGV G  G  G+ G KG  GPPG PG    G KGE G  G PG  G  G  GL G KG
Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLA--GHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683

Query: 737  EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            + G  G  G KGD+GE GE G+PG  G  GP G+ G
Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDG 2719



 Score =  409 bits (1050), Expect = e-113
 Identities = 247/541 (45%), Positives = 289/541 (53%), Gaps = 37/541 (6%)

Query: 247  PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306
            PG+PG PG  G+PG +G  GP G  G     E G  G  G PG  G++G RG  G  G K
Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479

Query: 307  GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKG 366
            GD+G PGP G  G +G +   GPPG  G +G  G  G PG  GP G PG    G+QG KG
Sbjct: 1480 GDRGFPGPLGEAGEKGER---GPPGPAGSRGLPGVAGRPGAKGPEGPPGP--TGRQGEKG 1534

Query: 367  ERGQEGRPGAPGPIGVGEPGQ------PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
            E G+ G P   GP   G  G+       GPRG  GV GERG PG   PG  G KG  G  
Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594

Query: 421  GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQ-GLPG 478
            GP GL G +  G  GD GP G +G  G PG  G  G +G  G +G  G +GP G  GLPG
Sbjct: 1595 GPIGLTGRA--GPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652

Query: 479  SKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGP 538
              GE G  G  G RGPV  G +G +G+PG  G  G PG  G  G  G+ G  G PG    
Sbjct: 1653 KAGERGLRGAPGVRGPV--GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710

Query: 539  EGPPG--KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGP 596
             GP    KG+PG +G EG +G KG+ G  G PG  G +G  G  GP G PG  + GP G 
Sbjct: 1711 TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG--VRGPAGE 1768

Query: 597  KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPP 652
            KGDRG PG+ G  G     + G  G  GP GP GA G  G    DG PG+ G +GLPGP 
Sbjct: 1769 KGDRGPPGLDGRSG-----LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS 1823

Query: 653  GPMGLRGVGDTGAKGEPGVRGPPG-PSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQG 710
            GP GL   G  G  G+PG+ G  G P  P   G +G KGD+G  G  G  GP G  G+ G
Sbjct: 1824 GPPGL--PGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881

Query: 711  IKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
            I G QGP G PGP G  G G PG  G  G +GD G+ G K   GE G PG++GL+G  G 
Sbjct: 1882 ILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSK---GEQGLPGERGLRGEPGS 1938

Query: 771  L 771
            +
Sbjct: 1939 V 1939



 Score =  210 bits (535), Expect = 5e-54
 Identities = 134/311 (43%), Positives = 161/311 (51%), Gaps = 33/311 (10%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-----------QKGEAGERGPGGIPG 289
            E  +G  G PG  G  G  G  G  G KG+ G++            KG+ GERGP G+  
Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGL-- 2546

Query: 290  YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349
              GDKG RG+ G PG KG KG PG  G  G  G++G+ GP G PG  G  G+ G PG  G
Sbjct: 2547 -DGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605

Query: 350  PYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE 405
              G  G  G    +G +G+KGERG +G  G  G    G+ G+ GP G  G+ G +G  GE
Sbjct: 2606 VPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGE--KGDKGEAGPPGRPGLAGHKGEMGE 2663

Query: 406  -GFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGP 462
             G PG  G  G EG  GP+G +G   + G KGD G  G +G  GI G  G  G  G  GP
Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723

Query: 463  IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521
             GPPG  GP G +GL G KGE         RGP G  V G  G PG+ G  G+ G PG  
Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGE---------RGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774

Query: 522  GAAGKKGEAGL 532
            G  G+KGEA L
Sbjct: 2775 GPRGEKGEAAL 2785



 Score =  174 bits (440), Expect = 6e-43
 Identities = 103/252 (40%), Positives = 133/252 (52%), Gaps = 25/252 (9%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQ-KGEAGERGPGGIPGYKGDKGERGECG 301
            +KG  G+PG  G+ G PG++G  GP+G PG A   G+ G  G  G+PG +G+KG+ G  G
Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMG 2620

Query: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQ 361
              G+KG++G  G  G  G +G +G  GPPG PG  G +G  GEPG PG  G+PG  G+  
Sbjct: 2621 PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGL-- 2678

Query: 362  QGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTG 421
             G KG+RG +G+PG  G    GE G+ G  G  G PG  G   +G  GP G  GS GP G
Sbjct: 2679 IGPKGDRGFDGQPGPKGD--QGEKGERGTPGIGGFPGPSG--NDGSAGPPGPPGSVGPRG 2734

Query: 422  PQGLQGLS------------------IKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463
            P+GLQG                      GE+G+ G  GP GP G  G  +  E  I+G +
Sbjct: 2735 PEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFV 2794

Query: 464  GPPGPQGPAGQG 475
                 Q  A QG
Sbjct: 2795 RQEMSQHCACQG 2806



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 50/190 (26%), Positives = 91/190 (47%), Gaps = 17/190 (8%)

Query: 798 ELVFVIDSSESVGPENFQIIKNFVK--TMADRVALDLATARIGIINYSHKVEKVANLKQF 855
           ++VF++D S S+G  NF+ +++F++   +    A      R   + YS        L   
Sbjct: 38  DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97

Query: 856 SSKDDFKLAVDNMQYLGEGTYTATA-LQAANDMF--EDARPGVKKVALVITDGQTDSRDK 912
            S  D   A+  + Y G  T T  A L  A+ +F  + ARPGV KV ++ITDG    + +
Sbjct: 98  GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCILITDG----KSQ 153

Query: 913 EKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDP-EHVYQFDDFFTLQDT 971
           + +    +      V++F +G +K  DP      +E+  +A+ P    + F + F++  T
Sbjct: 154 DLVDTAAQRLKGQGVKLFAVG-IKNADP------EELKRVASQPTSDFFFFVNDFSILRT 206

Query: 972 LKQKLFQKIC 981
           L   + +++C
Sbjct: 207 LLPLVSRRVC 216



 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 38/141 (26%), Positives = 53/141 (37%), Gaps = 33/141 (23%)

Query: 986  SYLVQIFGSS-SPQPGFGMSGEELSESTPEPQKEISESLSVTRDQDEDDKAPEPTWADDL 1044
            SY     GS     P   +S  E  E  P    E SE    + ++ +D +AP   W  D 
Sbjct: 2818 SYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAP---WDSDD 2874

Query: 1045 PATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNS---CARFW 1101
            P               S P+D             G+C  Y +RWY+     S   C  F 
Sbjct: 2875 PC--------------SLPLD------------EGSCTAYTLRWYHRAVTGSTEACHPFV 2908

Query: 1102 FSGCNGSGNRFNSEKECQETC 1122
            + GC G+ NRF + + C+  C
Sbjct: 2909 YGGCGGNANRFGTREACERRC 2929


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  448 bits (1152), Expect = e-125
 Identities = 268/600 (44%), Positives = 308/600 (51%), Gaps = 94/600 (15%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            + G PG PGPPG  G  G+ G  GPKG  G  + G+AGERG  G PG  G  G+ GE G 
Sbjct: 561  QDGRPGPPGPPGARGQAGVMGFPGPKGAAG--EPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQ 361
             G  G  G  G  G +GP G  G  G PG  GP G  G  GE G PG  G+PG  G  G+
Sbjct: 619  QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 362  QGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE----GF 407
            +G  GERG +G PG  GP G           G+ G PG  G +G PG +G+PGE    G 
Sbjct: 679  RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 408  PGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP-- 465
            PGPKG++G  GP G  G  G    G +G  GP+GP GP G PG   +GE G  GP GP  
Sbjct: 739  PGPKGDRGDAGPKGADGSPGKD--GVRGLTGPIGPPGPAGAPG--DKGESGPSGPAGPTG 794

Query: 466  ----------PGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGS 508
                      PGP GPAG        G PG+KGE G  G  G  GP G    GP G PG 
Sbjct: 795  ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA--GPAGPPGP 852

Query: 509  IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKGSKGNQGQ 564
            IG  G PG  G  G+AG  G  G PGA G  GPPG     G PGP G  GK+G KG +G+
Sbjct: 853  IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE 912

Query: 565  RGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQG 624
             G      P G PG +GP        PGPPGP G++G PG  G  G PG    GP+G+ G
Sbjct: 913  TG------PAGRPGEVGP--------PGPPGPAGEKGSPGADGPAGAPGTP--GPQGIAG 956

Query: 625  PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG 682
             RG VG PG +G+ G+PG+PGP G PG  GP G  G  G  G  G PG+ GPPG SG  G
Sbjct: 957  QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG 1016

Query: 683  V----------GTQGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPG 722
                       G+ G KGD G+ G  GPPG PG           G  G +GE GP G  G
Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076

Query: 723  PKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIG---EPGSPGKQGLQGPKGDLG 772
            P G +G        G  G KGE GE+GD G KG +G  G    PG PG  G QGP G  G
Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136



 Score =  444 bits (1142), Expect = e-124
 Identities = 265/571 (46%), Positives = 311/571 (54%), Gaps = 64/571 (11%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
           G  G PGPPG    PG +G +GP G PG  + G +G  GP G PG  G  G+ GE GKPG
Sbjct: 185 GPRGLPGPPGA---PGPQGFQGPPGEPG--EPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239

Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360
             G++G PGP G +G  G  G+ G  G  G  G  G KG+ GP GP G PG+PG     G
Sbjct: 240 RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPG 299

Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGP 419
           Q G +G  G+ GRPGAPGP G  G  G  G  GP G  G  G P  GFPG  G KG  GP
Sbjct: 300 QMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP--GFPGAVGAKGEAGP 357

Query: 420 TGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPG 478
            GP+G +G   ++GE G  GP G  GP G P  G+ G+ G +G  G PG  G    G PG
Sbjct: 358 QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP--GADGQPGAKGANGAPGIAG--APGFPG 413

Query: 479 SKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
           ++G  G  GP GP GP G           G  G KGEPG +G+ G PG  GE+G  G +G
Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473

Query: 529 EAGLPGARGPEGPPG-KGQPGPK---GDEGKKGSKGNQGQRGLPGPEGPKGEPGIM---G 581
           E   PG  G  GPPG +G PG +   G +G  G KG  G+RG PGP GPKG PG     G
Sbjct: 474 E---PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530

Query: 582 PFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG- 636
             G+PG    T  PG PGP G  G PG  G  G PG    GP G +G  G +G PG KG 
Sbjct: 531 EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP--GPPGARGQAGVMGFPGPKGA 588

Query: 637 DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQK 695
            G PG  G RG+PGPPG      VG  G  GE G +GPPGP+GP G  G QGP G  G +
Sbjct: 589 AGEPGKAGERGVPGPPG-----AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643

Query: 696 GLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHGER 741
           GLPGP GPPG     G QG+ G+         +G +GFPG +G  G  G  G +G +G  
Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703

Query: 742 GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           G+ G KGD G  G PGS G  GLQG  G+ G
Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734



 Score =  380 bits (976), Expect = e-105
 Identities = 240/518 (46%), Positives = 272/518 (52%), Gaps = 56/518 (10%)

Query: 244  KGDPGDPGPPGTHGNPGIKG---ERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299
            KGD G PG PG+ G PG++G   ERG  G PG    +G+AG +G  G PG  G +G  G 
Sbjct: 709  KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768

Query: 300  CGKPG---IKGDKGSPGPYGPKGP---RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353
             G PG     GDKG  GP GP GP   RG  G  G PG PGP GF G  G  G PG  G 
Sbjct: 769  IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828

Query: 354  PGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPK 411
            PG    G +G  G  G  G  G PGPIG VG PG  G RG  G PG  G PG  G  GP 
Sbjct: 829  PG--DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886

Query: 412  GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGP 471
            G  G+ GP GP G       G++G  GP G  GP G P           G +GPPGP GP
Sbjct: 887  GPSGNAGPPGPPG-----PAGKEGGKGPRGETGPAGRP-----------GEVGPPGPPGP 930

Query: 472  AGQ-GLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
            AG+ G PG+ G  G  G  GP+G  G    +G+ G +GE G  GLPG  G PG+ G +G 
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990

Query: 527  KGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGM 585
             GE G P   GP GPPG  G PG  G EG  G++G+ G+ G PG +G +GE G  GP G 
Sbjct: 991  SGERGPP---GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047

Query: 586  PGT-SIPGPPGP---KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD-GY 639
            PG    PGP GP    GDRG  G  G  G  G +  RGP G QGPRG  G  G +GD G 
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107

Query: 640  PGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLP 698
             G  G  GL GPPGP G  G  G +GA G  G RGPPG +G  G          G  GLP
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG--------KDGLNGLP 1159

Query: 699  GPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736
            GP GPP  G +G  G+ GP G PGP G  G   P   G
Sbjct: 1160 GPIGPP--GPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195



 Score =  293 bits (749), Expect = 8e-79
 Identities = 179/398 (44%), Positives = 210/398 (52%), Gaps = 50/398 (12%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGD-------- 293
            ++G+PG PGP G  G PG  G+ G KG PG+A  KG+AG  GP G  G  G         
Sbjct: 801  DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPG 860

Query: 294  -KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP---PG 349
             KG RG  G PG  G  G+ G  GP GP G  G  GPPG  G +G +G +GE GP   PG
Sbjct: 861  AKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPG 920

Query: 350  PYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERG 401
              G PG PG  G++G  G  G  G PG PGP G       VG PGQ G RG  G+PG  G
Sbjct: 921  EVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSG 980

Query: 402  LPGEGFP-GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGI 459
             PG+  P G  GE+G  GP GP GL G    GE G  G  G +G  G  G  G++G++G 
Sbjct: 981  EPGKQGPSGASGERGPPGPMGPPGLAGPP--GESGREGAPGAEGSPGRDGSPGAKGDRGE 1038

Query: 460  QGPIGPPG---------PQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEP 506
             GP GPPG         P GPAG+   G +GE G  GP GP GPVG     G QGP+G+ 
Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKS--GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096

Query: 507  GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566
            G  G  G  G+ G  G +G +G  G PG+ G +GP G    GP G  G  GS G  G+ G
Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS--GPAGPRGPPGSAGAPGKDG 1154

Query: 567  LP------GPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598
            L       GP GP+G  G  GP G PG   PGPPGP G
Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGP--PGPPGPPG 1190



 Score =  289 bits (739), Expect = 1e-77
 Identities = 177/406 (43%), Positives = 203/406 (50%), Gaps = 50/406 (12%)

Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463
           EG   P    GSE PT  +      ++G KGD GP GP+GP G PG  G  G+ G+ GP 
Sbjct: 88  EGECCPVCPDGSESPTDQETT---GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPP 144

Query: 464 GPPGPQGPAGQGLPGSKGEVGQMGPT-----GPRGPVGIGVQGPKGEPGSIGLPGQPGVP 518
           GPPGP GP G G        G   P        +   GI V GP G  G  GLPG PG P
Sbjct: 145 GPPGPPGPPGLG--------GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196

Query: 519 GEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEP 577
           G  G  G  GE G PGA GP GP G  G PG  GD+G+ G  G  G+RG PGP+G +G P
Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256

Query: 578 GIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVG 630
           G  G  GM G           G  GP G +G PG PG  G PG    GP+G+ G RG  G
Sbjct: 257 GTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQM--GPRGLPGERGRPG 314

Query: 631 APGLKG----DGYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPG 676
           APG  G    DG  G  GP G  GP GP G  G           G  G++G  GVRG PG
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374

Query: 677 PSGPRGV-------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728
           P GP G        G  G  G  G  G PG  G PG+ G++G  G QGP G PGPKG  G
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434

Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
             G PG KG+ G +G+ G  G +G  G  G  GK+G +G  G  GL
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480



 Score =  281 bits (719), Expect = 2e-75
 Identities = 168/367 (45%), Positives = 191/367 (52%), Gaps = 23/367 (6%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            KG  G  GPPG  G PG  G  GP G  GNA  G  G  GP G  G KG +GE G  G+P
Sbjct: 862  KGARGSAGPPGATGFPGAAGRVGPPGPSGNA--GPPGPPGPAGKEGGKGPRGETGPAGRP 919

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI---- 359
            G  G  G PGP G KG  G  G  G PG PGP+G  G +G  G PG  G  G PG+    
Sbjct: 920  GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979

Query: 360  GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGSE 417
            G+ G +G  G  G  G PGP+G  G  G PG  G EG PG  G PG +G PG KG++G  
Sbjct: 980  GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039

Query: 418  GPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476
            GP GP G       G  G  GPVGP G  G    G  G  G  GP+GP G +GPAG QG 
Sbjct: 1040 GPAGPPG-----APGAPGAPGPVGPAGKSG--DRGETGPAGPAGPVGPVGARGPAGPQGP 1092

Query: 477  PGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGA 535
             G KGE G+ G  G +G  G  G+QGP G PGS   PG+ G  G  G AG +G  G  GA
Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS---PGEQGPSGASGPAGPRGPPGSAGA 1149

Query: 536  RGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPG 595
             G +G    G PGP G  G +G  G+ G  G PGP GP G PG     G   + +P PP 
Sbjct: 1150 PGKDGL--NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA-GFDFSFLPQPPQ 1206

Query: 596  PKGDRGG 602
             K   GG
Sbjct: 1207 EKAHDGG 1213



 Score =  147 bits (371), Expect = 6e-35
 Identities = 101/243 (41%), Positives = 112/243 (46%), Gaps = 43/243 (17%)

Query: 565 RGLPGPEGPKGE------PGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPGLS 615
           +  PG E P+GE       G   P     T + GP G   P+G RG  G PG  G PG  
Sbjct: 79  KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP 138

Query: 616 IRGPKGVQGPRGPVGAPGLKGDGYP--------------------GVPGPRGLPGPPGPM 655
             G  G  GP GP G PGL G+  P                    G  GPRGLPGPPG  
Sbjct: 139 --GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196

Query: 656 GLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKG 713
           G +G  G  G  GEPG  GP GP GP G  G  G  G+ G+ G PG  GPPG   QG +G
Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG--PQGARG 254

Query: 714 EQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
             G  G PG KG  G       G  G +GD G  G KGE   PGSPG+ G  G  G  GL
Sbjct: 255 LPGTAGLPGMKGHRGFS-----GLDGAKGDAGPAGPKGE---PGSPGENGAPGQMGPRGL 306

Query: 774 TKE 776
             E
Sbjct: 307 PGE 309


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 1691

 Score =  447 bits (1150), Expect = e-125
 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%)

Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299
           GD G PGPPG  G PG     KGE+G +G PG   K G+ GE G  GIPG  GD G  GE
Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323

Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346
            G+ G KG KG  GP GP G   PR   GIT          G PG+ G +GF G +G PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398
            PGP G+     PG PG    G +G++G EG PG   PGP G+ G+PG PG  GP G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441

Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449
               P +    PGP G  GS G  G QG QG  +KG+KGD        G  GP G  G+P
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491
           G+             G +G+ G  GP G PG P  P   G PGSKGE G +    G  G 
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538
           +G +G     G+ G  G PG  GLPG PG  GE G    KGE G         LPG  GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590
            GPPG G PGP G++G +G  GN GQ G+PGP+G  G+    PG  G  G PG      +
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637
           PG PG  G  G PGIPG KGEPG+         GPKG  G  GP GAPG  G        
Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690
           G PG PGP+G     LPGPPGP GL G  G  G KG+ G  GPPGP G  G+ G  GPKG
Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799

Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739
           D G  G PGP GPPG    G++G  GP G PGP G  G HG+PG+KG+ G          
Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859

Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773
            ERG  G  G  G IG PGSP      G  G  G KG++G+
Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900



 Score =  441 bits (1135), Expect = e-123
 Identities = 271/597 (45%), Positives = 317/597 (53%), Gaps = 80/597 (13%)

Query: 244  KGDPGD--PGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGEC 300
            KG+PG   PGPPG  G PG KG  GPKG+ G     G  G  G  G+PG KGD G  G+ 
Sbjct: 748  KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807

Query: 301  GKPG--------IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF--------QGNKGE 344
            G  G        ++G  G PG  GP G  G+ GI G  GDPGP G         +G+ G 
Sbjct: 808  GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867

Query: 345  PGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGV 396
            PG PGP G PG+PG+       G  G KGE G  G PG PGP+G+ G  G PG +G +G+
Sbjct: 868  PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927

Query: 397  PGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIG------PVGPQGPMGIP 449
             G+ GLPG  G  G KGE G  GP GP     L  KGEKG+ G        GP+G  G+P
Sbjct: 928  QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987

Query: 450  GIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507
            G    G+ G+ G  G PGP GP G  GLPG  G +G  G  G  G +G  G QG +G PG
Sbjct: 988  G--DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 508  SIGLPGQPGVPGEDGAAGKKGEAG-----LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ 562
              G+PGQPG PG  G  G KG+ G     LPG  GP+G PG   PG  G+ G KGS G+ 
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL--PGYPGNPGIKGSVGDP 1103

Query: 563  GQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG--------- 613
            G  GLPG  G KG+PG+ G    PGT  PGPPGPKG  G PG PG  GEPG         
Sbjct: 1104 GLPGLPGTPGAKGQPGLPG---FPGT--PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 614  -------LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------ 660
                       G  G+ GP G  G PG  G G PG PG  GL G  G  GL G+      
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 661  ----GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQG 716
                G+ G  G PGV+GPPGP G  G   +GPKG+ G +G PG PGP G+  QG+ G +G
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF--QGLPGPEG 1276

Query: 717  PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            P G PG  G  G    G  G+ G  G  G KGD+G  G  G+PG+ GL G KGD GL
Sbjct: 1277 PPGLPGNGGIKGE--KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1331



 Score =  434 bits (1117), Expect = e-121
 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%)

Query: 238  KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295
            +ICE     PG PGPPG+ G+ G++GE+G KG+ G+        G  GP G PG  G  G
Sbjct: 449  EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351
              G  G PG KG+KG  G  GPKG  GI G  G PG PG KG  G+     G  G  G  
Sbjct: 504  PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405
            GSPGAPG+   G+ G  GQ+G PG PGP   GEPG     G RGP G PG  GLPG    
Sbjct: 564  GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 406  ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439
                  G PGP GEKG +G  G         P+G  G +I            G  GD+G 
Sbjct: 620  MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 440  VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491
             G  G  G PG+    GS+GE GI G IG PGP GP G     G PG+ G  G++G  GP
Sbjct: 680  PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 492  RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548
             GP G    GPKGEPG    G PG PG+PG  GA G KG+ G PG  GP G  G  G PG
Sbjct: 739  PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 549  PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595
            PKGD G  G  G  G  GLPG   +GP G PGI GP G PG          PGPPG    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 596  -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630
             P G+RG PGIPG  G       PGL            +G  G+ GP GP G        
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 631  -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676
              PGLKGD    G PG+PGP G         LPGPPGPM    +G  G KGEPG+ G PG
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 677  PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722
             SGP+G     G  G  G +GQ GLPGPPGP G           G  G+KG  G  GFPG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 723  PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749
            P+G  G                                  GLPG KGE G  G  G  G 
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 750  KGEIGEPGSPGKQGLQGPKGDLGL 773
            KG +G+PG PG  G  G KG  GL
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120



 Score =  434 bits (1115), Expect = e-121
 Identities = 286/658 (43%), Positives = 339/658 (51%), Gaps = 113/658 (17%)

Query: 243  EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284
            EKGDPG PG     PPG  G+PGI G  GP G PG+               KGE G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 285  ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318
                         G+PG KGD G +G+ G PG  G+KGS      PGP GP        K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 319  GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378
            G +G  G+ G PG  GPKG+QG  G+PG PG  G PG PG    G KG  G  G+PG  G
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021

Query: 379  PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422
            P G    +G+ G PGP+G EG PG  G+PG+    G PG KG+KG  G +        GP
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 423  QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473
            +G  GL    G  G  G VG  G  G+PG  G++G+ G+ G  G PGP GP G       
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 474  QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524
             GLPG  G VG      Q GP G +G  G  G+ GP G+ G  G PG   PG PG  G +
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201

Query: 525  GKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583
            G+KG+ GLPG  G  G PG KG+PG  G  G +G  G  G  G P  EGPKG PG  GP 
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPP 1260

Query: 584  GMPGTS----IPGPPGP---------KGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPV 629
            G PG +    +PGP GP         KG++G PG PG  G PGL   +GP G+QG  G  
Sbjct: 1261 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1320

Query: 630  GAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP- 688
            G  G+KGD  PG+PG  G PG  GP G+ G    G +GEPG+ GPPGP G  G   Q   
Sbjct: 1321 GLNGMKGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSII 1376

Query: 689  -KGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGD 743
             KGD G  G+PG PG      +G+ G QGPQG PGP G  G    +GLPG  G  G +GD
Sbjct: 1377 IKGDAGPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1431

Query: 744  VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799
             G  G  G  G  G PG  GLQGP G  G +      LIT        P+C +  L++
Sbjct: 1432 PGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1489



 Score =  418 bits (1075), Expect = e-116
 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291
           G PG PG PG  G PG  G  GP+G PG N  KGE G              GP GIPG K
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155

Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336
           G+            KG  G  G PGI+   G  G PGP GP GP G+ G  GPPG PGPK
Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377
           G     FQG KGE G  G  G PG PG               G QG+ G+RG  G PG  
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419
           GP G         GE G+PG RG  G  GE G PG           G PG  GEKG +G 
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450
           TGP G  GL                     + GEKG+ G  G QGP G+PG         
Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494
               G  GE+G +G  GPPG   P   GL G  G  G  GP GP GP             
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525
                                        +G G+ GP G+P   GLPG PG PG  G  G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512

Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574
           +KGE G  GA GP+G PG        G PG KG+ G      G KG++G+ G PG  G  
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627
           G PG  G  G+PG  +PGP G       KG+RG PG PG  G PG +   GP G  GP G
Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629

Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669
           PVG  G++G     G PG+PGP+G PG     PG  GL G           GD G  G+P
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725
           G+ G PG  G     G+G  GP G  G  G+PGPPG PG  G  G++G  GP GFPGPKG
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772
             G  LPG  G     G +G +G KGD+G  G PG PG+    GL GPKGD+G
Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802



 Score =  411 bits (1056), Expect = e-114
 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%)

Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296
           C+C   KG+ G+ G PG  G+PG+ G  GP+G PG   QKG+ G  GP G  G +G  G 
Sbjct: 38  CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            G  G PG+ G  G  G  GP+G  G  G  G  G PG  GF G +G PGPP        
Sbjct: 98  PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149

Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415
              G  G+KGE G       PGP   G PG PGP G +G+PG  G+PG  G PGP G  G
Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461
             GP    GP+G  GL+ +G KG+ G  G QGP G PG  S+           G+QG+ G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519
             GPPGP G  G   P  G KGE G+ G  G RG    G  G  G+PG  GLPG PG PG
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322

Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574
           E G  G+KG+ G  G  GP G     PG G   G KG+ G  G  G +G+RG PG +GP 
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381

Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
             PG+ GP   PG ++ GPPGP G  G  G  G +G PG+SI GP G+ G  G  G PG 
Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692
            G   P +P    +  PGPPGP G    GD G +GE GV+G  G +    +GT G  G  
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493

Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744
           GQ GLPG PGPPG  G  G KGE+G  G  GPKG  G     G PG  G  GE GD+   
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G KGDKGE+G PG+PG  GL G  G  GL
Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583



 Score =  301 bits (772), Expect = 2e-81
 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%)

Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409
           YG          GIKGE+G+ G PG  G      PG PG  GPEG PG RG  G+ G PG
Sbjct: 30  YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84

Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468
           P G KG  GP G  G  G    G  G  G  G  GP GIPG  G++GE+G  G  G PG 
Sbjct: 85  PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527
           QGP G  G+PG KGE G +        +   + GPKG PG  G PG  G+PG  G  G  
Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570
           G  G PG  GP GPPG   PGPKG+     +G KG KG QG +G PGP            
Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626
               +G +G PG  GP G PG  I GPPGP G  G  G  G +GEPG   RG  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306

Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674
           G  G PGL GD GYPG PG       +G  GPPGP GL     G G T G KG  G+ G 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728
           PG  G RG  G QGP G  G  G  + GPPGPPG+ G +G KG++GP G   PGP G  G
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
             G PG  G  G  G      D  EI EPG PG  G     GD GL  E+ +K
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474



 Score =  172 bits (435), Expect = 2e-42
 Identities = 104/233 (44%), Positives = 124/233 (53%), Gaps = 23/233 (9%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            E  KG+PG  GPPG  G  G +G  GP+G PG          G GGI G KG+ G+ G  
Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP--------GNGGIKGEKGNPGQPGLP 1299

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360
            G PG+KGD+G PG  G  G  G+ G+ G PG PG  GF G KG  G PG  G  G PG+ 
Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL- 1358

Query: 361  QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
                    G  G PG PGP G     + G  GP G+PG+ GL G   PGP+G +G  GPT
Sbjct: 1359 -------IGPPGPPGLPGPSGQSIIIK-GDAGPPGIPGQPGLKG--LPGPQGPQGLPGPT 1408

Query: 421  GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473
            GP G  G +  G  G  G  G +G  G+P  G  G +G+ GP GP G QGP G
Sbjct: 1409 GPPGDPGRN--GLPGFDGAGGRKGDPGLP--GQPGTRGLDGPPGPDGLQGPPG 1457



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%)

Query: 239  ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            I + + G PG PG PG  G P   G +GP+G PG    G  G+ G  G+PG+ G  G +G
Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1430

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331
            +   PG+ G  G+ G  GP GP G+QG  GPPG
Sbjct: 1431 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
           sapiens]
          Length = 1685

 Score =  447 bits (1150), Expect = e-125
 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%)

Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299
           GD G PGPPG  G PG     KGE+G +G PG   K G+ GE G  GIPG  GD G  GE
Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323

Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346
            G+ G KG KG  GP GP G   PR   GIT          G PG+ G +GF G +G PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398
            PGP G+     PG PG    G +G++G EG PG   PGP G+ G+PG PG  GP G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441

Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449
               P +    PGP G  GS G  G QG QG  +KG+KGD        G  GP G  G+P
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491
           G+             G +G+ G  GP G PG P  P   G PGSKGE G +    G  G 
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538
           +G +G     G+ G  G PG  GLPG PG  GE G    KGE G         LPG  GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590
            GPPG G PGP G++G +G  GN GQ G+PGP+G  G+    PG  G  G PG      +
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637
           PG PG  G  G PGIPG KGEPG+         GPKG  G  GP GAPG  G        
Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690
           G PG PGP+G     LPGPPGP GL G  G  G KG+ G  GPPGP G  G+ G  GPKG
Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799

Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739
           D G  G PGP GPPG    G++G  GP G PGP G  G HG+PG+KG+ G          
Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859

Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773
            ERG  G  G  G IG PGSP      G  G  G KG++G+
Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900



 Score =  440 bits (1131), Expect = e-123
 Identities = 277/608 (45%), Positives = 321/608 (52%), Gaps = 93/608 (15%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG-----ERGPGGIPGYKGDKGER 297
            KG PG PGPPG  G PG  G  GP G PG    KGE G       GP G+PG+KG  G  
Sbjct: 715  KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP- 773

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-----PYG 352
                    KGD+G PGP GP G  G+ G+ GP GD GP G  G  G PG PG     P G
Sbjct: 774  --------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 353  SPGAPG-IGQQGIKGERGQEGRPGAPG------PIGVGEPGQPGPRGPEGVPGERGLPGE 405
             PG PG IGQ G+ G  G++G PG PG      P   G PG PG  GP G PG  GLPG+
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 406  ----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQ 460
                GFPG KGE G  GP GP G   L I G  G  G  G  G  G PG+ G  GE+G +
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943

Query: 461  GPIGPPGPQGPAGQGLPGSKGEVGQMG------PTGPRGPVGI-------------GVQG 501
            G  G PGP GP    L GSKGE G+ G       +GP+G  G+             G+ G
Sbjct: 944  GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
            P G  G+ GLPGQPG+ G  G  G  G+ G PG +G EGPPG     GQPG  G  G+KG
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063

Query: 558  SKGNQG--QRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGF 608
             KG+ G    GLPG  GPKGEPG+ G  G PG         +PG PG  G +G PG+PGF
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 609  KGEPGLSIRGPKGVQGPRGPVGAPG----LKGDGYPGVPGPRGLPGPPGPMGLRGVGDTG 664
             G PG    GPKG+ GP G  G PG    + G G+PG PGP G  G PG  G+ G    G
Sbjct: 1124 PGTPGPP--GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG--PAG 1179

Query: 665  AKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGE--- 714
             KGEPG  G   P  P   G  G KGD G  G+PG PG PG       +G  G++G    
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239

Query: 715  --------QGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765
                    +GP+G PGP+G  G  GLPG +G  G  G+ G KG+KG  G+PG PG  GL+
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1299

Query: 766  GPKGDLGL 773
            G +G  GL
Sbjct: 1300 GDQGPPGL 1307



 Score =  437 bits (1124), Expect = e-122
 Identities = 285/653 (43%), Positives = 341/653 (52%), Gaps = 109/653 (16%)

Query: 243  EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284
            EKGDPG PG     PPG  G+PGI G  GP G PG+               KGE G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 285  ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318
                         G+PG KGD G +G+ G PG  G+KGS      PGP GP        K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 319  GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378
            G +G  G+ G PG  GPKG+QG  G+PG PG  G PG PG    G KG  G  G+PG  G
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021

Query: 379  PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422
            P G    +G+ G PGP+G EG PG  G+PG+    G PG KG+KG  G +        GP
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 423  QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473
            +G  GL    G  G  G VG  G  G+PG  G++G+ G+ G  G PGP GP G       
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 474  QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524
             GLPG  G VG      Q GP G +G  G  G+ GP G+ G  G PG   PG PG  G +
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201

Query: 525  GKKGEAGLPGARG------PEGPPG-KGQPGPKGDEGKKGSKGN--QGQRGLPGPEGPKG 575
            G+KG+ GLPG  G      P+G PG  G PG +G  G  GS G   +G +G PGP+GP G
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPG 1261

Query: 576  EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGL 634
             PG+ GP G PG  +PG  G KG++G PG PG  G PGL   +GP G+QG  G  G  G+
Sbjct: 1262 RPGLPGPEGPPG--LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319

Query: 635  KGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP--KGDT 692
            KGD  PG+PG  G PG  GP G+ G    G +GEPG+ GPPGP G  G   Q    KGD 
Sbjct: 1320 KGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1375

Query: 693  GQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKG 748
            G  G+PG PG      +G+ G QGPQG PGP G  G    +GLPG  G  G +GD G  G
Sbjct: 1376 GPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430

Query: 749  DKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799
              G  G  G PG  GLQGP G  G +      LIT        P+C +  L++
Sbjct: 1431 QPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1483



 Score =  434 bits (1117), Expect = e-121
 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%)

Query: 238  KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295
            +ICE     PG PGPPG+ G+ G++GE+G KG+ G+        G  GP G PG  G  G
Sbjct: 449  EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351
              G  G PG KG+KG  G  GPKG  GI G  G PG PG KG  G+     G  G  G  
Sbjct: 504  PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405
            GSPGAPG+   G+ G  GQ+G PG PGP   GEPG     G RGP G PG  GLPG    
Sbjct: 564  GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 406  ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439
                  G PGP GEKG +G  G         P+G  G +I            G  GD+G 
Sbjct: 620  MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 440  VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491
             G  G  G PG+    GS+GE GI G IG PGP GP G     G PG+ G  G++G  GP
Sbjct: 680  PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 492  RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548
             GP G    GPKGEPG    G PG PG+PG  GA G KG+ G PG  GP G  G  G PG
Sbjct: 739  PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 549  PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595
            PKGD G  G  G  G  GLPG   +GP G PGI GP G PG          PGPPG    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 596  -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630
             P G+RG PGIPG  G       PGL            +G  G+ GP GP G        
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 631  -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676
              PGLKGD    G PG+PGP G         LPGPPGPM    +G  G KGEPG+ G PG
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 677  PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722
             SGP+G     G  G  G +GQ GLPGPPGP G           G  G+KG  G  GFPG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 723  PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749
            P+G  G                                  GLPG KGE G  G  G  G 
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 750  KGEIGEPGSPGKQGLQGPKGDLGL 773
            KG +G+PG PG  G  G KG  GL
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120



 Score =  418 bits (1075), Expect = e-116
 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291
           G PG PG PG  G PG  G  GP+G PG N  KGE G              GP GIPG K
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155

Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336
           G+            KG  G  G PGI+   G  G PGP GP GP G+ G  GPPG PGPK
Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377
           G     FQG KGE G  G  G PG PG               G QG+ G+RG  G PG  
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419
           GP G         GE G+PG RG  G  GE G PG           G PG  GEKG +G 
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450
           TGP G  GL                     + GEKG+ G  G QGP G+PG         
Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494
               G  GE+G +G  GPPG   P   GL G  G  G  GP GP GP             
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525
                                        +G G+ GP G+P   GLPG PG PG  G  G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512

Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574
           +KGE G  GA GP+G PG        G PG KG+ G      G KG++G+ G PG  G  
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627
           G PG  G  G+PG  +PGP G       KG+RG PG PG  G PG +   GP G  GP G
Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629

Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669
           PVG  G++G     G PG+PGP+G PG     PG  GL G           GD G  G+P
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725
           G+ G PG  G     G+G  GP G  G  G+PGPPG PG  G  G++G  GP GFPGPKG
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772
             G  LPG  G     G +G +G KGD+G  G PG PG+    GL GPKGD+G
Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802



 Score =  411 bits (1056), Expect = e-114
 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%)

Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296
           C+C   KG+ G+ G PG  G+PG+ G  GP+G PG   QKG+ G  GP G  G +G  G 
Sbjct: 38  CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            G  G PG+ G  G  G  GP+G  G  G  G  G PG  GF G +G PGPP        
Sbjct: 98  PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149

Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415
              G  G+KGE G       PGP   G PG PGP G +G+PG  G+PG  G PGP G  G
Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461
             GP    GP+G  GL+ +G KG+ G  G QGP G PG  S+           G+QG+ G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519
             GPPGP G  G   P  G KGE G+ G  G RG    G  G  G+PG  GLPG PG PG
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322

Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574
           E G  G+KG+ G  G  GP G     PG G   G KG+ G  G  G +G+RG PG +GP 
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381

Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
             PG+ GP   PG ++ GPPGP G  G  G  G +G PG+SI GP G+ G  G  G PG 
Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692
            G   P +P    +  PGPPGP G    GD G +GE GV+G  G +    +GT G  G  
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493

Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744
           GQ GLPG PGPPG  G  G KGE+G  G  GPKG  G     G PG  G  GE GD+   
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G KGDKGE+G PG+PG  GL G  G  GL
Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583



 Score =  301 bits (772), Expect = 2e-81
 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%)

Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409
           YG          GIKGE+G+ G PG  G      PG PG  GPEG PG RG  G+ G PG
Sbjct: 30  YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84

Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468
           P G KG  GP G  G  G    G  G  G  G  GP GIPG  G++GE+G  G  G PG 
Sbjct: 85  PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527
           QGP G  G+PG KGE G +        +   + GPKG PG  G PG  G+PG  G  G  
Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570
           G  G PG  GP GPPG   PGPKG+     +G KG KG QG +G PGP            
Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626
               +G +G PG  GP G PG  I GPPGP G  G  G  G +GEPG   RG  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306

Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674
           G  G PGL GD GYPG PG       +G  GPPGP GL     G G T G KG  G+ G 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728
           PG  G RG  G QGP G  G  G  + GPPGPPG+ G +G KG++GP G   PGP G  G
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
             G PG  G  G  G      D  EI EPG PG  G     GD GL  E+ +K
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474



 Score =  171 bits (432), Expect = 5e-42
 Identities = 103/222 (46%), Positives = 118/222 (53%), Gaps = 21/222 (9%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            E  KG+PG  GPP   G PG+ G  GP G PGN   G  GE+G  G PG  G  G +G+ 
Sbjct: 1248 EGPKGNPGPQGPP---GRPGLPGPEGPPGLPGNG--GIKGEKGNPGQPGLPGLPGLKGDQ 1302

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
            G PG++G+ G PG  G KG  G+ G+ G PG  GP G  G+ G  G PG  G PG PG+ 
Sbjct: 1303 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1362

Query: 360  GQQG----IKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPK 411
            G  G    IKG+ G  G PG PG  G+    G  G PGP GP G PG  GLP  GF G  
Sbjct: 1363 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GFDGAG 1420

Query: 412  GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453
            G KG  G  G  G +GL      G  GP G QGP G PG  S
Sbjct: 1421 GRKGDPGLPGQPGTRGLD-----GPPGPDGLQGPPGPPGTSS 1457



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%)

Query: 239  ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            I + + G PG PG PG  G P   G +GP+G PG    G  G+ G  G+PG+ G  G +G
Sbjct: 1370 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1424

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331
            +   PG+ G  G+ G  GP GP G+QG  GPPG
Sbjct: 1425 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
           sapiens]
          Length = 1688

 Score =  447 bits (1150), Expect = e-125
 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%)

Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299
           GD G PGPPG  G PG     KGE+G +G PG   K G+ GE G  GIPG  GD G  GE
Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323

Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346
            G+ G KG KG  GP GP G   PR   GIT          G PG+ G +GF G +G PG
Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383

Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398
            PGP G+     PG PG    G +G++G EG PG   PGP G+ G+PG PG  GP G  G
Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441

Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449
               P +    PGP G  GS G  G QG QG  +KG+KGD        G  GP G  G+P
Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491
           G+             G +G+ G  GP G PG P  P   G PGSKGE G +    G  G 
Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559

Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538
           +G +G     G+ G  G PG  GLPG PG  GE G    KGE G         LPG  GP
Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590
            GPPG G PGP G++G +G  GN GQ G+PGP+G  G+    PG  G  G PG      +
Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637
           PG PG  G  G PGIPG KGEPG+         GPKG  G  GP GAPG  G        
Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739

Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690
           G PG PGP+G     LPGPPGP GL G  G  G KG+ G  GPPGP G  G+ G  GPKG
Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799

Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739
           D G  G PGP GPPG    G++G  GP G PGP G  G HG+PG+KG+ G          
Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859

Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773
            ERG  G  G  G IG PGSP      G  G  G KG++G+
Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900



 Score =  440 bits (1131), Expect = e-123
 Identities = 296/651 (45%), Positives = 327/651 (50%), Gaps = 136/651 (20%)

Query: 244  KGDPG------DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG-------PG--GIP 288
            KG+PG      + GPPG  G PG+ G  GP G PG    G  GE+G       PG  GIP
Sbjct: 590  KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649

Query: 289  GYKGDKGER----------------------------GECGKPGIKGDKGSPGPYG---- 316
            G KGD G+                             G+ G PGI G KG PG  G    
Sbjct: 650  GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP 709

Query: 317  -PKGPRGIQGITGPPG------------DPGPKGFQGNKGEPG--PPGPYGSPGAPGI-G 360
             P GP+G  GI GPPG             PGP GF G KGEPG   PGP G PG PG  G
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 361  QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERG---LPGEGFPGPKGEKGS 416
              G KG+RG  G PG PG  G+ G PG  G  GP G PG  G   LPG G  GP G  G 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 417  EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ- 474
             GP G  GL G  I GEKGD GP G   P G PG  GS G  G  GPIGPPG  G  G+ 
Sbjct: 830  PGPIGQPGLHG--IPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886

Query: 475  ---GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEA 530
               G PG+KGE+G MGP GP GP+GI G  G  G  G  GL GQPG+PG  G  G KGE 
Sbjct: 887  GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946

Query: 531  GLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS- 589
            GLPG  GP  P            G KG KG  G  G+PG  GPKG  G+ G  G PG S 
Sbjct: 947  GLPGPPGPMDP---------NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSG 997

Query: 590  ---IPGPPGPKGDRGGPGIPGFKGEPGLS-------IRGPKGVQGPRGPVGAPGL----- 634
               +PGPPGPKG+ G PG PG  G PGL          GP+GV+GP GP G PG      
Sbjct: 998  QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPG 1057

Query: 635  -------KGD------GYPGVPGPRG---LPGPPGPMGLRG-VGDTG---------AKGE 668
                   KGD      G PG+PGP+G   LPG PG  G++G VGD G         AKG+
Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 669  PGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGP 723
            PG+ G PG  GP G  G  GP G+ G  G PGP G  G+    G  G KG+ G  G PGP
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177

Query: 724  KGTMGHGLPGQKG--EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G  G   PGQ G    G  G  G  G KG+ G PG PG  GL GPKG+ G
Sbjct: 1178 AGQKGE--PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226



 Score =  436 bits (1121), Expect = e-122
 Identities = 277/611 (45%), Positives = 316/611 (51%), Gaps = 96/611 (15%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG-----ERGPGGIPGYKGDKGER 297
            KG PG PGPPG  G PG  G  GP G PG    KGE G       GP G+PG+KG  G  
Sbjct: 715  KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP- 773

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-----PYG 352
                    KGD+G PGP GP G  G+ G+ GP GD GP G  G  G PG PG     P G
Sbjct: 774  --------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825

Query: 353  SPGAPG-IGQQGIKGERGQEGRPGAPG------PIGVGEPGQPGPRGPEGVPGERGLPGE 405
             PG PG IGQ G+ G  G++G PG PG      P   G PG PG  GP G PG  GLPG+
Sbjct: 826  PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885

Query: 406  ----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQ 460
                GFPG KGE G  GP GP G   L I G  G  G  G  G  G PG+ G  GE+G +
Sbjct: 886  AGASGFPGTKGEMGMMGPPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943

Query: 461  GPIGPPGPQGPAGQGLPGSKGEVGQMG------PTGPRGPVGI-------------GVQG 501
            G  G PGP GP    L GSKGE G+ G       +GP+G  G+             G+ G
Sbjct: 944  GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
            P G  G+ GLPGQPG+ G  G  G  G+ G PG +G EGPPG     GQPG  G  G+KG
Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063

Query: 558  SKGNQG--QRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGF 608
             KG+ G    GLPG  GPKGEPG+ G  G PG         +PG PG  G +G PG+PGF
Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123

Query: 609  KGEPGLSIRGPKGVQGPRGPVGAPG----LKGDGYPGVPGPRGLPGPPGPMGLRGVGDTG 664
             G PG    GPKG+ GP G  G PG    + G G+PG PGP G  G PG  G+ G    G
Sbjct: 1124 PGTPGPP--GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG--PAG 1179

Query: 665  AKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGP 723
             KGEPG  G   P  P   G  G KGD G  G+PG PG PG  G  G  G  G QG PGP
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239

Query: 724  KGTMG---------------------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
             G+ G                      GLPG +G  G  G+ G KG+KG  G+PG PG  
Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1299

Query: 763  GLQGPKGDLGL 773
            GL+G +G  GL
Sbjct: 1300 GLKGDQGPPGL 1310



 Score =  434 bits (1117), Expect = e-121
 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%)

Query: 238  KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295
            +ICE     PG PGPPG+ G+ G++GE+G KG+ G+        G  GP G PG  G  G
Sbjct: 449  EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351
              G  G PG KG+KG  G  GPKG  GI G  G PG PG KG  G+     G  G  G  
Sbjct: 504  PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405
            GSPGAPG+   G+ G  GQ+G PG PGP   GEPG     G RGP G PG  GLPG    
Sbjct: 564  GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619

Query: 406  ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439
                  G PGP GEKG +G  G         P+G  G +I            G  GD+G 
Sbjct: 620  MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679

Query: 440  VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491
             G  G  G PG+    GS+GE GI G IG PGP GP G     G PG+ G  G++G  GP
Sbjct: 680  PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 492  RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548
             GP G    GPKGEPG    G PG PG+PG  GA G KG+ G PG  GP G  G  G PG
Sbjct: 739  PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796

Query: 549  PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595
            PKGD G  G  G  G  GLPG   +GP G PGI GP G PG          PGPPG    
Sbjct: 797  PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856

Query: 596  -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630
             P G+RG PGIPG  G       PGL            +G  G+ GP GP G        
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 631  -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676
              PGLKGD    G PG+PGP G         LPGPPGPM    +G  G KGEPG+ G PG
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 677  PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722
             SGP+G     G  G  G +GQ GLPGPPGP G           G  G+KG  G  GFPG
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 723  PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749
            P+G  G                                  GLPG KGE G  G  G  G 
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 750  KGEIGEPGSPGKQGLQGPKGDLGL 773
            KG +G+PG PG  G  G KG  GL
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120



 Score =  434 bits (1117), Expect = e-121
 Identities = 286/655 (43%), Positives = 338/655 (51%), Gaps = 110/655 (16%)

Query: 243  EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284
            EKGDPG PG     PPG  G+PGI G  GP G PG+               KGE G  GP
Sbjct: 844  EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903

Query: 285  ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318
                         G+PG KGD G +G+ G PG  G+KGS      PGP GP        K
Sbjct: 904  PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963

Query: 319  GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378
            G +G  G+ G PG  GPKG+QG  G+PG PG  G PG PG    G KG  G  G+PG  G
Sbjct: 964  GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021

Query: 379  PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422
            P G    +G+ G PGP+G EG PG  G+PG+    G PG KG+KG  G +        GP
Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081

Query: 423  QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473
            +G  GL    G  G  G VG  G  G+PG  G++G+ G+ G  G PGP GP G       
Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141

Query: 474  QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524
             GLPG  G VG      Q GP G +G  G  G+ GP G+ G  G PG   PG PG  G +
Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201

Query: 525  GKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583
            G+KG+ GLPG  G  G PG KG+PG  G  G +G  G  G  G P  EGPKG PG  GP 
Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPP 1260

Query: 584  GMPG-TSIPGPPGP---------KGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAP 632
            G PG   +PGP GP         KG++G PG PG  G PGL   +GP G+QG  G  G  
Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1320

Query: 633  GLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP--KG 690
            G+KGD  PG+PG  G PG  GP G+ G    G +GEPG+ GPPGP G  G   Q    KG
Sbjct: 1321 GMKGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1376

Query: 691  DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGK 746
            D G  G+PG PG      +G+ G QGPQG PGP G  G    +GLPG  G  G +GD G 
Sbjct: 1377 DAGPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431

Query: 747  KGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799
             G  G  G  G PG  GLQGP G  G +      LIT        P+C +  L++
Sbjct: 1432 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1486



 Score =  418 bits (1075), Expect = e-116
 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291
           G PG PG PG  G PG  G  GP+G PG N  KGE G              GP GIPG K
Sbjct: 96  GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155

Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336
           G+            KG  G  G PGI+   G  G PGP GP GP G+ G  GPPG PGPK
Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215

Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377
           G     FQG KGE G  G  G PG PG               G QG+ G+RG  G PG  
Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275

Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419
           GP G         GE G+PG RG  G  GE G PG           G PG  GEKG +G 
Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335

Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450
           TGP G  GL                     + GEKG+ G  G QGP G+PG         
Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395

Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494
               G  GE+G +G  GPPG   P   GL G  G  G  GP GP GP             
Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455

Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525
                                        +G G+ GP G+P   GLPG PG PG  G  G
Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512

Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574
           +KGE G  GA GP+G PG        G PG KG+ G      G KG++G+ G PG  G  
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627
           G PG  G  G+PG  +PGP G       KG+RG PG PG  G PG +   GP G  GP G
Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629

Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669
           PVG  G++G     G PG+PGP+G PG     PG  GL G           GD G  G+P
Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689

Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725
           G+ G PG  G     G+G  GP G  G  G+PGPPG PG  G  G++G  GP GFPGPKG
Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749

Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772
             G  LPG  G     G +G +G KGD+G  G PG PG+    GL GPKGD+G
Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802



 Score =  411 bits (1056), Expect = e-114
 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%)

Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296
           C+C   KG+ G+ G PG  G+PG+ G  GP+G PG   QKG+ G  GP G  G +G  G 
Sbjct: 38  CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97

Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            G  G PG+ G  G  G  GP+G  G  G  G  G PG  GF G +G PGPP        
Sbjct: 98  PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149

Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415
              G  G+KGE G       PGP   G PG PGP G +G+PG  G+PG  G PGP G  G
Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204

Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461
             GP    GP+G  GL+ +G KG+ G  G QGP G PG  S+           G+QG+ G
Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264

Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519
             GPPGP G  G   P  G KGE G+ G  G RG    G  G  G+PG  GLPG PG PG
Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322

Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574
           E G  G+KG+ G  G  GP G     PG G   G KG+ G  G  G +G+RG PG +GP 
Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381

Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
             PG+ GP   PG ++ GPPGP G  G  G  G +G PG+SI GP G+ G  G  G PG 
Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436

Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692
            G   P +P    +  PGPPGP G    GD G +GE GV+G  G +    +GT G  G  
Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493

Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744
           GQ GLPG PGPPG  G  G KGE+G  G  GPKG  G     G PG  G  GE GD+   
Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553

Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G KGDKGE+G PG+PG  GL G  G  GL
Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583



 Score =  301 bits (772), Expect = 2e-81
 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%)

Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409
           YG          GIKGE+G+ G PG  G      PG PG  GPEG PG RG  G+ G PG
Sbjct: 30  YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84

Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468
           P G KG  GP G  G  G    G  G  G  G  GP GIPG  G++GE+G  G  G PG 
Sbjct: 85  PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142

Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527
           QGP G  G+PG KGE G +        +   + GPKG PG  G PG  G+PG  G  G  
Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194

Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570
           G  G PG  GP GPPG   PGPKG+     +G KG KG QG +G PGP            
Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252

Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626
               +G +G PG  GP G PG  I GPPGP G  G  G  G +GEPG   RG  G  G  
Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306

Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674
           G  G PGL GD GYPG PG       +G  GPPGP GL     G G T G KG  G+ G 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728
           PG  G RG  G QGP G  G  G  + GPPGPPG+ G +G KG++GP G   PGP G  G
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
             G PG  G  G  G      D  EI EPG PG  G     GD GL  E+ +K
Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474



 Score =  173 bits (438), Expect = 9e-43
 Identities = 103/222 (46%), Positives = 118/222 (53%), Gaps = 18/222 (8%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            E  KG+PG  GPPG  G  G+ G  GP G PGN   G  GE+G  G PG  G  G +G+ 
Sbjct: 1248 EGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNG--GIKGEKGNPGQPGLPGLPGLKGDQ 1305

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
            G PG++G+ G PG  G KG  G+ G+ G PG  GP G  G+ G  G PG  G PG PG+ 
Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1365

Query: 360  GQQG----IKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPK 411
            G  G    IKG+ G  G PG PG  G+    G  G PGP GP G PG  GLP  GF G  
Sbjct: 1366 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GFDGAG 1423

Query: 412  GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453
            G KG  G  G  G +GL      G  GP G QGP G PG  S
Sbjct: 1424 GRKGDPGLPGQPGTRGLD-----GPPGPDGLQGPPGPPGTSS 1460



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%)

Query: 239  ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            I + + G PG PG PG  G P   G +GP+G PG    G  G+ G  G+PG+ G  G +G
Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1427

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331
            +   PG+ G  G+ G  GP GP G+QG  GPPG
Sbjct: 1428 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score =  446 bits (1148), Expect = e-125
 Identities = 273/648 (42%), Positives = 335/648 (51%), Gaps = 129/648 (19%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGG------------I 287
           +G+PG+PG PG  G  G +G  GP G PG+     + G+AGERGP G            +
Sbjct: 224 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 283

Query: 288 PGYKGDKG------ERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGP 335
           PG KG +G       +GE G PG+KG+ GSP      GP GP+G  G +G TGP G  G 
Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 343

Query: 336 KGFQGNKGEPGPPGPYGSPGAPGI----------------GQQGIKGERGQEGRPGAPGP 379
           +G  G  G  GPPGP G  G PG                 G +G +G RG+ G PG+PGP
Sbjct: 344 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 403

Query: 380 IGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQG-------L 428
            G     G  G PG +G  G PG  G P  GFPGP+G  G +G TGP G +G        
Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAP--GFPGPRGPPGPQGATGPLGPKGQTGEPGIA 461

Query: 429 SIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQG-PAGQGLPGSK 480
             KGE+G  G  GP GP G PG        G++GE G  GPIGPPG +G P  +G PG  
Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521

Query: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
           G  G  G  G RGP G+   GPKG  G  G PG+PG+PG  G  G+ G+AG  G  GP G
Sbjct: 522 GLAGPKGAPGERGPSGLA--GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 579

Query: 541 PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG------------ 587
            PG+ G+PGP G +   G++G  G  G PGP+G  GEPG  G  G+PG            
Sbjct: 580 APGEDGRPGPPGPQ---GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636

Query: 588 -TSIPGPPGP------KGDRGGPGIPGFKGEPG----------------LSIRGPKGVQG 624
            T   GPPGP      +G++G PG  GF+G PG                    G  G+ G
Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696

Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSG 679
           PRG  G PG +G  G  G+ GPRGLPG PG  G +G     G  GA+G PG++G PG  G
Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756

Query: 680 PRGV-GTQGPKGDTGQK------------GLPGPPGPPG-YGSQGIKGEQGPQGFPGPKG 725
             G+ G +G +GD G+K            GL GP GPPG  G+ G KGE GP   PGP G
Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP---PGPAG 813

Query: 726 TMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           + G  G PG++GE G  G  G  G  G  G+PG+ G+QG  G KGD G
Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861



 Score =  442 bits (1137), Expect = e-124
 Identities = 286/643 (44%), Positives = 335/643 (52%), Gaps = 95/643 (14%)

Query: 213 LLSDPTLVDKIQDRL--DILFEKKCERKICECEKGDP-GDPGPPGTHGNPG-IKGERGPK 268
           +L D  + + ++D L  +I F + C   IC  +     G PGP G  G PG IK   GPK
Sbjct: 62  VLCDDIICEDVKDCLSPEIPFGECCP--ICPTDLATASGQPGPKGQKGEPGDIKDIVGPK 119

Query: 269 GNPGNAQKGEAGERGPGGIPGYKGDKGE---RGECGKPGIKGDKGSPGPYGPKGPRGIQG 325
           G PG   +G AGE+GP G  G KG+KG    RG  G+PG  G+ G PGP GP GP G+ G
Sbjct: 120 GPPG--PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGG 177

Query: 326 ---------------------ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQQG 363
                                + GP G  GP+G  G  G PGP G  G+PG PG  G  G
Sbjct: 178 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSG 237

Query: 364 IKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTG 421
             G RG  G PG PG  G  G+PG+ G RGP G  G RG PG  G PG KG +G  G  G
Sbjct: 238 PMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297

Query: 422 PQGLQGL-SIKGEKG---DIGPVGPQGPMGIPG----------IGSQGEQGIQGPIGPPG 467
            +G  G   +KGE G   + G  GP GP G+PG           G++G  G  GP GPPG
Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357

Query: 468 PQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGV---PGEDGA 523
           P GPAG  G PG+ G  G+ GPTG RGP G   QGP+GEPG+ G PG  G    PG DG 
Sbjct: 358 PVGPAGGPGFPGAPGAKGEAGPTGARGPEG--AQGPRGEPGTPGSPGPAGASGNPGTDGI 415

Query: 524 AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPG---PEGPKGEPGI 579
            G KG AG PG  G  G PG +G PGP+G  G  G KG  G+ G+ G    +GPKGEPG 
Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475

Query: 580 MGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626
            GP G PG +               GP GP G+RG PG  GF G+ GL+  GPKG  G R
Sbjct: 476 AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA--GPKGAPGER 533

Query: 627 GPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPS 678
           GP G  G KG        G PG+PG RGL G PG  G +G VG +GA GE G  GPPGP 
Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593

Query: 679 GPRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPG 733
           G RG    +G  GPKG  G+ G  G  G PG  G +G+ G+ G  G  GP        PG
Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP--------PG 645

Query: 734 QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
             G  GERG+ G  G  G  G PG PG  G  G  GD G+  E
Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGE 688



 Score =  439 bits (1128), Expect = e-123
 Identities = 282/682 (41%), Positives = 337/682 (49%), Gaps = 155/682 (22%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERG-PG--GIPGYKGD 293
            KG+PG  GP G  G  G +G+RG +G PG         ++G  G RG PG  G+ G KG 
Sbjct: 470  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG------FQGNKGEPGP 347
             GERG  G  G KG  G PG  G  G  G +G+TG PGD GP+G        G  G PGP
Sbjct: 530  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 348  PGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGP 393
            PGP G+ G PG+       G  G  G+ G++G PGAPG  G+       G  G PGP GP
Sbjct: 590  PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649

Query: 394  EGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLS-------------IKGEKGD 436
             G  GE+G PG    +G PGP G  G  G  G QG+ G +               GE+G 
Sbjct: 650  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709

Query: 437  IGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494
             G  G QGP G+PG  G+ G +G  GP GPPG QGP G QG+PG +G  G  GP G RG 
Sbjct: 710  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769

Query: 495  VG-------------------IGVQGP---KGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532
            VG                   IG  GP    GE G +G PG  G  G  GA G++GE G 
Sbjct: 770  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829

Query: 533  PGARGPEGPPGK-GQPGPKGDEGKKGSKGN------QGQRGLPGPEGPKGE--------- 576
            PG  G  GPPG  GQPG KG++G+ G KG+      QG  G PGP+GP G          
Sbjct: 830  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889

Query: 577  ---------PGIMGPFGMPGTS----IPGPPGP------KGDRGGPGIPGFKGEPGLS-- 615
                     PG  G  G PG++     PGPPGP      KG RG  G PG  GEPGL   
Sbjct: 890  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949

Query: 616  -----------IRGPKGVQGPRGP---------VGAPGLKGD-GYPGVPGPRGLPG---- 650
                         GP G +GP GP         VG PG +G+ G+PG+PGP G PG    
Sbjct: 950  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 651  --------PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLP 698
                    PPGP+G  G+  TG  GEPG  G PG  GP G     G +G +G+TG  G P
Sbjct: 1010 PGASGDRGPPGPVGPPGL--TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067

Query: 699  GPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK 750
            G PGPPG        G QG +GE G QG  GP G  G  G+ G +G  G++G+ G+ G++
Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1127

Query: 751  GEIGEPGSPGKQGLQGPKGDLG 772
            G  G  G  G QGL GP G  G
Sbjct: 1128 GLKGHRGFTGLQGLPGPPGPSG 1149



 Score =  435 bits (1119), Expect = e-121
 Identities = 283/648 (43%), Positives = 321/648 (49%), Gaps = 129/648 (19%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG---DKGERGE 299
            E G PG PGP G  G PG+ G  GPKG   N + G+AGE+G  G PG +G     GE G 
Sbjct: 583  EDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 640

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG------PYGS 353
             G PG  G  G  G  G  GP G QG+ GPPG PG  G  G++G PG  G      P G 
Sbjct: 641  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 700

Query: 354  PGAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG- 404
             G PG     G QG++G RG  G PG  GP G     G PG  GP G +G+PGERG  G 
Sbjct: 701  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760

Query: 405  ---------------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449
                           EG PG  G +G  GP GP G  G +  GEKG++GP GP G  G  
Sbjct: 761  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN--GEKGEVGPPGPAGSAGAR 818

Query: 450  GI-GSQGEQGIQGPIG---PPGPQGPAG----QGLPGSKGEVGQMGPTGP------RGPV 495
            G  G +GE G  GP G   PPG  G  G    QG  G KG+ G  GP GP      +GP 
Sbjct: 819  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878

Query: 496  GI-------GVQGPKGE------------PGSIGLPGQPGVPGEDGAAGKKG-------- 528
            G+       G QGP G             PGS G PG PG PG  G  G KG        
Sbjct: 879  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938

Query: 529  -EAGLPGARGPEGPPG-KGQPG---PKGDEGKKGSKGNQGQRG---LPGPEGPKGEPGIM 580
              AG PG +GP GPPG KG+PG   P G EG  G +G  GQRG   LPG  G +G PG+ 
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 581  GPFGMPGTSIPGPPGPKGDRGGPG------IPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
            GP G PG    G PG  GDRG PG      + G  GEPG    G  G  GP G  GA G+
Sbjct: 999  GPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGRE--GSPGADGPPGRDGAAGV 1054

Query: 635  KGD-------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQ 686
            KGD       G PG PGP G PGP GP G +G  D G  G  G  GP GP+G RG+ G Q
Sbjct: 1055 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGAQGPMGPSGPAGARGIQGPQ 1112

Query: 687  GPKGD------------------TGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727
            GP+GD                  TG +GLPGPPGP G  G+ G  G  GP+G PGP G  
Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1172

Query: 728  G----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771
            G    +G+PG  G  G RG  G+ G  G  G PG PG  G  GP  D+
Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1220



 Score =  434 bits (1115), Expect = e-121
 Identities = 258/587 (43%), Positives = 311/587 (52%), Gaps = 70/587 (11%)

Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301
           E G PG+ G PG  G  G+ GERG  G  G A  +G  G+ GP G PG  G  G  G  G
Sbjct: 310 ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369

Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360
            PG KG+ G  G  GP+G +G +G  G PG PGP G  GN G  G PG  GS GAPGI G
Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429

Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
             G  G RG  G  GA GP+  G  GQ G  G  G  GE+G  GE  PGP G +G+ GP 
Sbjct: 430 APGFPGPRGPPGPQGATGPL--GPKGQTGEPGIAGFKGEQGPKGE--PGPAGPQGAPGPA 485

Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG------ 473
           G +G +G   +GE G +GP+GP G  G PG  G  G+ G+ GP G PG +GP+G      
Sbjct: 486 GEEGKRG--ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543

Query: 474 ----------QGLPGSKGEVGQMGPTGPRGPVG-------------IGVQGPKGEPGSIG 510
                      GLPG++G  G+ G  GP+G VG              G QG +G+PG +G
Sbjct: 544 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 603

Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQG 563
            PG  G  GE G AG+KG  G PG RG  G  G+       G  GP G+ G++G+ G  G
Sbjct: 604 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663

Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQ 623
            +GLPGP GP GE G  G  G+PG +  G PG  G RG  G PG +G P     G +G+Q
Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGVPGEA--GAPGLVGPRGERGFPGERGSP-----GAQGLQ 716

Query: 624 GPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672
           GPRG  G PG  G        G PG  GP GL G PG  G  G+    GD G  GE G  
Sbjct: 717 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 776

Query: 673 GPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727
           G PG  G RG    +G  GP G  G+KG  GPPGP G  G++G  GE+G  G PGP G  
Sbjct: 777 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836

Query: 728 GHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           G   PG  G+ G +G+ G+ G KG+ G PG  G  G  GP+G  G+T
Sbjct: 837 GP--PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 881



 Score =  429 bits (1103), Expect = e-120
 Identities = 271/592 (45%), Positives = 314/592 (53%), Gaps = 67/592 (11%)

Query: 244  KGDPGDPGPPGTHGNPGI---KGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            +G  G  GP G  G PGI   KGE+GPKG PG A  G  G  GP G  G +G +GE G  
Sbjct: 443  QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGV 500

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
            G  G  G++G+PG  G  G  G+ G  G PG+ GP G  G KG  G PG  G PG PG  
Sbjct: 501  GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560

Query: 360  ------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPG---ER 400
                        G+ G  G  G++GRPG PGP G  G+PG    PGP+G  G PG   E+
Sbjct: 561  GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620

Query: 401  GLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG---PMGIPGIGS 453
            GLPG     G PG  GE G+ GP GP G  G   +GE+G  GP G QG   P G PG G 
Sbjct: 621  GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGG 678

Query: 454  Q-GEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKG 504
            + G+QG+ G  G PG  GP G+ G PG +G  G  G  GPRG  G        G  GP G
Sbjct: 679  KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738

Query: 505  EPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
             PG+ G PG  G+PGE GAAG    KG+ G  G +GPEG PGK    G  GP G  G  G
Sbjct: 739  PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 798

Query: 558  SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSI 616
            + G +G+ G PGP G  G  G  G  G  G   PGP G  G  G  G PG KGE G    
Sbjct: 799  ANGEKGEVGPPGPAGSAGARGAPGERGETGP--PGPAGFAGPPGADGQPGAKGEQGEAGQ 856

Query: 617  RGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGV 671
            +G  G  GP+GP GAPG +G  G  G  G RG  GPPG  G  G    VG  G+ G PG 
Sbjct: 857  KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916

Query: 672  RGPPGPSG---PRGV-GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGT 726
             GPPGPSG   P+G  G  GP G  G+ GL GP GPPG  G  G  G  G +G PGP+G 
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 727  MGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
             G     GLPGQ+GE G  G  G  G+ G+ G PG+ G +G  GP G  GLT
Sbjct: 977  AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028



 Score =  424 bits (1091), Expect = e-118
 Identities = 268/633 (42%), Positives = 312/633 (49%), Gaps = 118/633 (18%)

Query: 243 EKGDPGDPGP------PGTHGNPGIKGERGPKGNPG----------------------NA 274
           +KG+ G PGP      PGT GNPG  G  GP G PG                        
Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198

Query: 275 QKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG 334
            +G  G  GP G PG  G  G +G  G PG  G+ G  GP GP+GP G  G  G  G+ G
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 335 PKGFQGNKGEPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPG 386
             G  G +G PGP G  G PG PG+       G  G+ G +G+ G PG  G  G  GE G
Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318

Query: 387 QPGPRGPEGVPGERG----------------------------LPGEGFPGPKGEKGSEG 418
            PGP GP G+PGERG                              G GFPG  G KG  G
Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 378

Query: 419 PTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQG 470
           PTG +G +G    +GE G  G  GP G  G PG        GS G  GI G  G PGP+G
Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438

Query: 471 PAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
           P     PG +G  G +GP G  G  GI    G QGPKGEPG  G  G PG  GE+G  G 
Sbjct: 439 P-----PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493

Query: 527 KGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
           +GE   PG  GP GPPG       +G PG  G  G KG+ G +G  GL GP+G  G+PG 
Sbjct: 494 RGE---PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550

Query: 580 MGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
            G  G+PG    T  PG  GP+G  G  G PG  G PG    GP+G +G  G +G PG K
Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--GPQGARGQPGVMGFPGPK 608

Query: 636 G-DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693
           G +G PG  G +GLPG PG  GL      G  GE G  GPPGP+GP G  G QG  G +G
Sbjct: 609 GANGEPGKAGEKGLPGAPGLRGL-----PGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663

Query: 694 QKGLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHG 739
            +GLPGPPGPPG     G QG+ GE         +G +GFPG +G+ G  GL G +G  G
Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 723

Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G  G KG  G  G PG+ G  GLQG  G+ G
Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756



 Score =  294 bits (753), Expect = 3e-79
 Identities = 194/464 (41%), Positives = 222/464 (47%), Gaps = 87/464 (18%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGE 299
            EKG+ G PGP G+ G  G  GERG  G PG A  G AG  G  G PG KG++GE   +G+
Sbjct: 802  EKGEVGPPGPAGSAGARGAPGERGETGPPGPA--GFAGPPGADGQPGAKGEQGEAGQKGD 859

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
             G PG +G  G+PGP GP G  G +G  G  G PG  GF G  G  GPPG  G+PG PG 
Sbjct: 860  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919

Query: 359  ---IGQQGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE 405
                G+ G KG RG  G PG  G  G+          GEPG  GP G EG PG +GL G+
Sbjct: 920  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979

Query: 406  ----GFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGE 456
                G PG +GE+G  G  GP G  G     G  GD GP GP GP G+ G     G +G 
Sbjct: 980  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039

Query: 457  QGIQGPIG------------------------PPGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             G  GP G                        PPG  GPAG  G  G +GE G  GP GP
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099

Query: 492  RGPVGI-GVQGPKG---------EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541
             GP G  G+QGP+G         EPG  GL G  G  G  G  G  G +G  GA GP GP
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159

Query: 542  PG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEG---------PKGEPGIMGPFGMPGTSIP 591
             G +G PGP G  GK G+ G  G  G PGP G         P G PG  GP        P
Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP--------P 1211

Query: 592  GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
            GPPGP     G  +  F G  G   +GP  +Q  R    A GL+
Sbjct: 1212 GPPGP-----GIDMSAFAG-LGPREKGPDPLQYMRADQAAGGLR 1249


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score =  446 bits (1148), Expect = e-125
 Identities = 273/648 (42%), Positives = 335/648 (51%), Gaps = 129/648 (19%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGG------------I 287
           +G+PG+PG PG  G  G +G  GP G PG+     + G+AGERGP G            +
Sbjct: 155 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 214

Query: 288 PGYKGDKG------ERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGP 335
           PG KG +G       +GE G PG+KG+ GSP      GP GP+G  G +G TGP G  G 
Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 274

Query: 336 KGFQGNKGEPGPPGPYGSPGAPGI----------------GQQGIKGERGQEGRPGAPGP 379
           +G  G  G  GPPGP G  G PG                 G +G +G RG+ G PG+PGP
Sbjct: 275 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 334

Query: 380 IGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQG-------L 428
            G     G  G PG +G  G PG  G P  GFPGP+G  G +G TGP G +G        
Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAP--GFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392

Query: 429 SIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQG-PAGQGLPGSK 480
             KGE+G  G  GP GP G PG        G++GE G  GPIGPPG +G P  +G PG  
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452

Query: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
           G  G  G  G RGP G+   GPKG  G  G PG+PG+PG  G  G+ G+AG  G  GP G
Sbjct: 453 GLAGPKGAPGERGPSGLA--GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 510

Query: 541 PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG------------ 587
            PG+ G+PGP G +   G++G  G  G PGP+G  GEPG  G  G+PG            
Sbjct: 511 APGEDGRPGPPGPQ---GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567

Query: 588 -TSIPGPPGP------KGDRGGPGIPGFKGEPG----------------LSIRGPKGVQG 624
            T   GPPGP      +G++G PG  GF+G PG                    G  G+ G
Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627

Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSG 679
           PRG  G PG +G  G  G+ GPRGLPG PG  G +G     G  GA+G PG++G PG  G
Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687

Query: 680 PRGV-GTQGPKGDTGQK------------GLPGPPGPPG-YGSQGIKGEQGPQGFPGPKG 725
             G+ G +G +GD G+K            GL GP GPPG  G+ G KGE GP   PGP G
Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP---PGPAG 744

Query: 726 TMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           + G  G PG++GE G  G  G  G  G  G+PG+ G+QG  G KGD G
Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792



 Score =  442 bits (1137), Expect = e-124
 Identities = 278/614 (45%), Positives = 321/614 (52%), Gaps = 90/614 (14%)

Query: 239 ICECEKGDPGDPGPPGTHGNPG-IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE- 296
           +  C+  D   PGP G  G PG IK   GPKG PG   +G AGE+GP G  G KG+KG  
Sbjct: 20  VLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPG--PQGPAGEQGPRGDRGDKGEKGAP 77

Query: 297 --RGECGKPGIKGDKGSPGPYGPKGPRGIQG---------------------ITGPPGDP 333
             RG  G+PG  G+ G PGP GP GP G+ G                     + GP G  
Sbjct: 78  GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137

Query: 334 GPKGFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPR 391
           GP+G  G  G PGP G  G+PG PG  G  G  G RG  G PG PG  G  G+PG+ G R
Sbjct: 138 GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 197

Query: 392 GPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKG---DIGPVGPQGPM 446
           GP G  G RG PG  G PG KG +G  G  G +G  G   +KGE G   + G  GP GP 
Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257

Query: 447 GIPG----------IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPV 495
           G+PG           G++G  G  GP GPPGP GPAG  G PG+ G  G+ GPTG RGP 
Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317

Query: 496 GIGVQGPKGEPGSIGLPGQPGV---PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKG 551
           G   QGP+GEPG+ G PG  G    PG DG  G KG AG PG  G  G PG +G PGP+G
Sbjct: 318 G--AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375

Query: 552 DEGKKGSKGNQGQRGLPG---PEGPKGEPGIMGPFGMPGTSIP-------------GPPG 595
             G  G KG  G+ G+ G    +GPKGEPG  GP G PG +               GP G
Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 435

Query: 596 PKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGL 648
           P G+RG PG  GF G+ GL+  GPKG  G RGP G  G KG        G PG+PG RGL
Sbjct: 436 PPGERGAPGNRGFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 493

Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGP 703
            G PG  G +G VG +GA GE G  GPPGP G RG    +G  GPKG  G+ G  G  G 
Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553

Query: 704 PGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
           PG  G +G+ G+ G  G  GP        PG  G  GERG+ G  G  G  G PG PG  
Sbjct: 554 PGAPGLRGLPGKDGETGAAGP--------PGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 763 GLQGPKGDLGLTKE 776
           G  G  GD G+  E
Sbjct: 606 GEGGKPGDQGVPGE 619



 Score =  439 bits (1128), Expect = e-123
 Identities = 282/682 (41%), Positives = 337/682 (49%), Gaps = 155/682 (22%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERG-PG--GIPGYKGD 293
            KG+PG  GP G  G  G +G+RG +G PG         ++G  G RG PG  G+ G KG 
Sbjct: 401  KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG------FQGNKGEPGP 347
             GERG  G  G KG  G PG  G  G  G +G+TG PGD GP+G        G  G PGP
Sbjct: 461  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 348  PGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGP 393
            PGP G+ G PG+       G  G  G+ G++G PGAPG  G+       G  G PGP GP
Sbjct: 521  PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580

Query: 394  EGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLS-------------IKGEKGD 436
             G  GE+G PG    +G PGP G  G  G  G QG+ G +               GE+G 
Sbjct: 581  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640

Query: 437  IGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494
             G  G QGP G+PG  G+ G +G  GP GPPG QGP G QG+PG +G  G  GP G RG 
Sbjct: 641  PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700

Query: 495  VG-------------------IGVQGP---KGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532
            VG                   IG  GP    GE G +G PG  G  G  GA G++GE G 
Sbjct: 701  VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760

Query: 533  PGARGPEGPPGK-GQPGPKGDEGKKGSKGN------QGQRGLPGPEGPKGE--------- 576
            PG  G  GPPG  GQPG KG++G+ G KG+      QG  G PGP+GP G          
Sbjct: 761  PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820

Query: 577  ---------PGIMGPFGMPGTS----IPGPPGP------KGDRGGPGIPGFKGEPGLS-- 615
                     PG  G  G PG++     PGPPGP      KG RG  G PG  GEPGL   
Sbjct: 821  QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880

Query: 616  -----------IRGPKGVQGPRGP---------VGAPGLKGD-GYPGVPGPRGLPG---- 650
                         GP G +GP GP         VG PG +G+ G+PG+PGP G PG    
Sbjct: 881  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 651  --------PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLP 698
                    PPGP+G  G+  TG  GEPG  G PG  GP G     G +G +G+TG  G P
Sbjct: 941  PGASGDRGPPGPVGPPGL--TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998

Query: 699  GPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK 750
            G PGPPG        G QG +GE G QG  GP G  G  G+ G +G  G++G+ G+ G++
Sbjct: 999  GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1058

Query: 751  GEIGEPGSPGKQGLQGPKGDLG 772
            G  G  G  G QGL GP G  G
Sbjct: 1059 GLKGHRGFTGLQGLPGPPGPSG 1080



 Score =  435 bits (1119), Expect = e-121
 Identities = 283/648 (43%), Positives = 321/648 (49%), Gaps = 129/648 (19%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG---DKGERGE 299
            E G PG PGP G  G PG+ G  GPKG   N + G+AGE+G  G PG +G     GE G 
Sbjct: 514  EDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 571

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG------PYGS 353
             G PG  G  G  G  G  GP G QG+ GPPG PG  G  G++G PG  G      P G 
Sbjct: 572  AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 631

Query: 354  PGAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG- 404
             G PG     G QG++G RG  G PG  GP G     G PG  GP G +G+PGERG  G 
Sbjct: 632  RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691

Query: 405  ---------------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449
                           EG PG  G +G  GP GP G  G +  GEKG++GP GP G  G  
Sbjct: 692  AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN--GEKGEVGPPGPAGSAGAR 749

Query: 450  GI-GSQGEQGIQGPIG---PPGPQGPAG----QGLPGSKGEVGQMGPTGP------RGPV 495
            G  G +GE G  GP G   PPG  G  G    QG  G KG+ G  GP GP      +GP 
Sbjct: 750  GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809

Query: 496  GI-------GVQGPKGE------------PGSIGLPGQPGVPGEDGAAGKKG-------- 528
            G+       G QGP G             PGS G PG PG PG  G  G KG        
Sbjct: 810  GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869

Query: 529  -EAGLPGARGPEGPPG-KGQPG---PKGDEGKKGSKGNQGQRG---LPGPEGPKGEPGIM 580
              AG PG +GP GPPG KG+PG   P G EG  G +G  GQRG   LPG  G +G PG+ 
Sbjct: 870  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 581  GPFGMPGTSIPGPPGPKGDRGGPG------IPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
            GP G PG    G PG  GDRG PG      + G  GEPG    G  G  GP G  GA G+
Sbjct: 930  GPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGRE--GSPGADGPPGRDGAAGV 985

Query: 635  KGD-------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQ 686
            KGD       G PG PGP G PGP GP G +G  D G  G  G  GP GP+G RG+ G Q
Sbjct: 986  KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGAQGPMGPSGPAGARGIQGPQ 1043

Query: 687  GPKGD------------------TGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727
            GP+GD                  TG +GLPGPPGP G  G+ G  G  GP+G PGP G  
Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1103

Query: 728  G----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771
            G    +G+PG  G  G RG  G+ G  G  G PG PG  G  GP  D+
Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1151



 Score =  434 bits (1115), Expect = e-121
 Identities = 258/587 (43%), Positives = 311/587 (52%), Gaps = 70/587 (11%)

Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301
           E G PG+ G PG  G  G+ GERG  G  G A  +G  G+ GP G PG  G  G  G  G
Sbjct: 241 ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 300

Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360
            PG KG+ G  G  GP+G +G +G  G PG PGP G  GN G  G PG  GS GAPGI G
Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 360

Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
             G  G RG  G  GA GP+  G  GQ G  G  G  GE+G  GE  PGP G +G+ GP 
Sbjct: 361 APGFPGPRGPPGPQGATGPL--GPKGQTGEPGIAGFKGEQGPKGE--PGPAGPQGAPGPA 416

Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG------ 473
           G +G +G   +GE G +GP+GP G  G PG  G  G+ G+ GP G PG +GP+G      
Sbjct: 417 GEEGKRG--ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474

Query: 474 ----------QGLPGSKGEVGQMGPTGPRGPVG-------------IGVQGPKGEPGSIG 510
                      GLPG++G  G+ G  GP+G VG              G QG +G+PG +G
Sbjct: 475 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 534

Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQG 563
            PG  G  GE G AG+KG  G PG RG  G  G+       G  GP G+ G++G+ G  G
Sbjct: 535 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594

Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQ 623
            +GLPGP GP GE G  G  G+PG +  G PG  G RG  G PG +G P     G +G+Q
Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGVPGEA--GAPGLVGPRGERGFPGERGSP-----GAQGLQ 647

Query: 624 GPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672
           GPRG  G PG  G        G PG  GP GL G PG  G  G+    GD G  GE G  
Sbjct: 648 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 707

Query: 673 GPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727
           G PG  G RG    +G  GP G  G+KG  GPPGP G  G++G  GE+G  G PGP G  
Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767

Query: 728 GHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           G   PG  G+ G +G+ G+ G KG+ G PG  G  G  GP+G  G+T
Sbjct: 768 GP--PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 812



 Score =  429 bits (1103), Expect = e-120
 Identities = 271/592 (45%), Positives = 314/592 (53%), Gaps = 67/592 (11%)

Query: 244 KGDPGDPGPPGTHGNPGI---KGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
           +G  G  GP G  G PGI   KGE+GPKG PG A  G  G  GP G  G +G +GE G  
Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGV 431

Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
           G  G  G++G+PG  G  G  G+ G  G PG+ GP G  G KG  G PG  G PG PG  
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491

Query: 360 ------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPG---ER 400
                       G+ G  G  G++GRPG PGP G  G+PG    PGP+G  G PG   E+
Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551

Query: 401 GLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG---PMGIPGIGS 453
           GLPG     G PG  GE G+ GP GP G  G   +GE+G  GP G QG   P G PG G 
Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGG 609

Query: 454 Q-GEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKG 504
           + G+QG+ G  G PG  GP G+ G PG +G  G  G  GPRG  G        G  GP G
Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 669

Query: 505 EPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
            PG+ G PG  G+PGE GAAG    KG+ G  G +GPEG PGK    G  GP G  G  G
Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 729

Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSI 616
           + G +G+ G PGP G  G  G  G  G  G   PGP G  G  G  G PG KGE G    
Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGERGETGP--PGPAGFAGPPGADGQPGAKGEQGEAGQ 787

Query: 617 RGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGV 671
           +G  G  GP+GP GAPG +G  G  G  G RG  GPPG  G  G    VG  G+ G PG 
Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847

Query: 672 RGPPGPSG---PRGV-GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGT 726
            GPPGPSG   P+G  G  GP G  G+ GL GP GPPG  G  G  G  G +G PGP+G 
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 727 MGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            G     GLPGQ+GE G  G  G  G+ G+ G PG+ G +G  GP G  GLT
Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959



 Score =  424 bits (1091), Expect = e-118
 Identities = 268/633 (42%), Positives = 312/633 (49%), Gaps = 118/633 (18%)

Query: 243 EKGDPGDPGP------PGTHGNPGIKGERGPKGNPG----------------------NA 274
           +KG+ G PGP      PGT GNPG  G  GP G PG                        
Sbjct: 70  DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129

Query: 275 QKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG 334
            +G  G  GP G PG  G  G +G  G PG  G+ G  GP GP+GP G  G  G  G+ G
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189

Query: 335 PKGFQGNKGEPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPG 386
             G  G +G PGP G  G PG PG+       G  G+ G +G+ G PG  G  G  GE G
Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249

Query: 387 QPGPRGPEGVPGERG----------------------------LPGEGFPGPKGEKGSEG 418
            PGP GP G+PGERG                              G GFPG  G KG  G
Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309

Query: 419 PTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQG 470
           PTG +G +G    +GE G  G  GP G  G PG        GS G  GI G  G PGP+G
Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369

Query: 471 PAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
           P     PG +G  G +GP G  G  GI    G QGPKGEPG  G  G PG  GE+G  G 
Sbjct: 370 P-----PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424

Query: 527 KGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
           +GE   PG  GP GPPG       +G PG  G  G KG+ G +G  GL GP+G  G+PG 
Sbjct: 425 RGE---PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481

Query: 580 MGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
            G  G+PG    T  PG  GP+G  G  G PG  G PG    GP+G +G  G +G PG K
Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--GPQGARGQPGVMGFPGPK 539

Query: 636 G-DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693
           G +G PG  G +GLPG PG  GL      G  GE G  GPPGP+GP G  G QG  G +G
Sbjct: 540 GANGEPGKAGEKGLPGAPGLRGL-----PGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594

Query: 694 QKGLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHG 739
            +GLPGPPGPPG     G QG+ GE         +G +GFPG +G+ G  GL G +G  G
Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 654

Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G  G KG  G  G PG+ G  GLQG  G+ G
Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687



 Score =  416 bits (1069), Expect = e-116
 Identities = 273/627 (43%), Positives = 309/627 (49%), Gaps = 151/627 (24%)

Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP---KGPRGIQGITGPPGDPGPKGFQGNKGE 344
           PG KG KGE G+     I G KG PGP GP   +GPRG +G  G  G PGP+G  G  G 
Sbjct: 31  PGPKGQKGEPGDI--KDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88

Query: 345 PGPPGPYGSPGAPG----------------------------IGQQGIKGERGQEGRPGA 376
           PG PGP G PG PG                             G  G  G RG  G  GA
Sbjct: 89  PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148

Query: 377 PGPIGV----GEPGQP---GPRGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGL 428
           PGP G     GEPG+P   GP GP G PG  G PG +G  G  G+ G  GP GPQG +G 
Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208

Query: 429 ----------------------------SIKGEK---GDIGPVGPQGPMGIPG------- 450
                                        +KGE    G+ G  GP GP G+PG       
Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268

Query: 451 ---IGSQGEQGIQGPIGPPGPQGPA-GQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP 506
               G++G  G  GP GPPGP GPA G G PG+ G  G+ GPTG RGP   G QGP+GEP
Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE--GAQGPRGEP 326

Query: 507 GSIGLPGQPGV---PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQ 562
           G+ G PG  G    PG DG  G KG AG PG  G  G PG +G PGP+G  G  G KG  
Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386

Query: 563 GQRGL---PGPEGPKGEPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIP 606
           G+ G+    G +GPKGEPG  GP G PG +               GP GP G+RG PG  
Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446

Query: 607 GFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG 659
           GF G+ GL+  GPKG  G RGP G  G KG        G PG+PG RGL G PG  G +G
Sbjct: 447 GFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG 504

Query: 660 -VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPK------GDTGQKGLPGPP------- 701
            VG +GA GE G  GPPGP G RG    +G  GPK      G  G+KGLPG P       
Sbjct: 505 KVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 564

Query: 702 --------GPPG-------YGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGD-- 743
                   GPPG        G QG  G  G QG PGP G  G  G PG +G  GE G   
Sbjct: 565 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG 624

Query: 744 -VGKKGDKGEIGEPGSPGKQGLQGPKG 769
            VG +G++G  GE GSPG QGLQGP+G
Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRG 651



 Score =  294 bits (753), Expect = 3e-79
 Identities = 194/464 (41%), Positives = 222/464 (47%), Gaps = 87/464 (18%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGE 299
            EKG+ G PGP G+ G  G  GERG  G PG A  G AG  G  G PG KG++GE   +G+
Sbjct: 733  EKGEVGPPGPAGSAGARGAPGERGETGPPGPA--GFAGPPGADGQPGAKGEQGEAGQKGD 790

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
             G PG +G  G+PGP GP G  G +G  G  G PG  GF G  G  GPPG  G+PG PG 
Sbjct: 791  AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850

Query: 359  ---IGQQGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE 405
                G+ G KG RG  G PG  G  G+          GEPG  GP G EG PG +GL G+
Sbjct: 851  PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910

Query: 406  ----GFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGE 456
                G PG +GE+G  G  GP G  G     G  GD GP GP GP G+ G     G +G 
Sbjct: 911  RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970

Query: 457  QGIQGPIG------------------------PPGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             G  GP G                        PPG  GPAG  G  G +GE G  GP GP
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 492  RGPVGI-GVQGPKG---------EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541
             GP G  G+QGP+G         EPG  GL G  G  G  G  G  G +G  GA GP GP
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090

Query: 542  PG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEG---------PKGEPGIMGPFGMPGTSIP 591
             G +G PGP G  GK G+ G  G  G PGP G         P G PG  GP        P
Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP--------P 1142

Query: 592  GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
            GPPGP     G  +  F G  G   +GP  +Q  R    A GL+
Sbjct: 1143 GPPGP-----GIDMSAFAG-LGPREKGPDPLQYMRADQAAGGLR 1180


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  446 bits (1148), Expect = e-125
 Identities = 271/596 (45%), Positives = 320/596 (53%), Gaps = 76/596 (12%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGK 302
           +G PG PG PG  G+ G KG  GPKG  G    KGEAG  GP G  G  G +G  GE G+
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346

Query: 303 ------PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG------------PKGFQGNKGE 344
                 PG +G  G PG  GP GP GI G +G PG+PG            P+G QG +GE
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 345 PGPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402
            GPPGP GSPG PG IG  G  G +G  G PG  GP G  G PG PGP+G  G  G RG 
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 403 PGE-GFPGPKGEKGSEGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPG- 450
           PG+ G PG KGE G +G  GP G+QG             +G+ G +GP GP G  G PG 
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 451 IGSQGEQGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPVGI----GVQGPKGE 505
            G  G  G+ GP G  G +GP G   P GS+G+ G+ G  G  G  G+    GVQGP+G+
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 506 PGSIGLPGQ---PGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGK 555
            G +G PG+   PG PG  G  G+ G  GLPG +G  G PGK       G PG +G  GK
Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK 646

Query: 556 KGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-- 613
            G  G  G  G PG  G +GE G  GP G  G  +PGPPGP G+ G PG  G  G+PG  
Sbjct: 647 DGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG--LPGPPGPPGEGGKPGDQGVPGDPGAV 704

Query: 614 --LSIRGPKGVQGPRGPVGAPGLKG----------DGYPGVPGPRGLPGPPGPMGLRGVG 661
             L  RG +G  G RG  G  GL G          DG  G PGP G PG  GP GL+G+ 
Sbjct: 705 GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM- 763

Query: 662 DTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQG 716
                GE G+ G PGP G RG     G +G  G+ G +GLPGP GPPG  G  G KGE G
Sbjct: 764 ----PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819

Query: 717 PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           P+G  GP G+ G+  PG +GE+G  G VG  G +G  G+PG  G+ G  G KGD G
Sbjct: 820 PRGLVGPPGSRGN--PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAG 873



 Score =  438 bits (1126), Expect = e-122
 Identities = 268/579 (46%), Positives = 307/579 (53%), Gaps = 64/579 (11%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301
            E+G+ G PGP G  G PG  G  G  G PG+    G+ G  GP G  G +G+ GERGE G
Sbjct: 664  ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723

Query: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---PGPPGPYGSPGAPG 358
              G+ G+KG  G +GP GP+G  G +G PGD GP G QG  GE    G PGP G  G  G
Sbjct: 724  ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG--G 781

Query: 359  IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPGE-GFPGP 410
            IG++G +G  G +G  G PGP+G        GE G+PGPRG  G PG RG PG  G  GP
Sbjct: 782  IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGP 841

Query: 411  KGEKGSEGPTGPQGLQGLSIK----GEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPP 466
             G  G  GP GP G  G+  +    G+KGD G  GPQG  G PG    G  G+ G  G  
Sbjct: 842  TGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG--PHGPNGVPGLKGGR 899

Query: 467  GPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525
            G QGP G  G PGS G VG  GP G  GP G     P GEPG  G PG  G PG  G  G
Sbjct: 900  GTQGPPGATGFPGSAGRVGPPGPAGAPGPAG-----PLGEPGKEGPPGLRGDPGSHGRVG 954

Query: 526  KKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFG 584
             +G AG PG  G +G PG+ GQPGP G  G  G+ G +G  G+PG  G +G PG+ GP G
Sbjct: 955  DRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014

Query: 585  MPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637
             PG    T   G  GP G  G PG  G  GEPG    GP G  G  G  GA G +GD   
Sbjct: 1015 TPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE--GPAGNDGTPGRDGAVGERGDRGD 1072

Query: 638  -GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP------------PGPSGPRG-V 683
             G  G+PG +G PG PGP+G    GD G +G+PG RGP            PGP GPRG  
Sbjct: 1073 PGPAGLPGSQGAPGTPGPVG--APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDK 1130

Query: 684  GTQGPKGDTGQKG---------LPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPG 733
            G  G +GD GQKG         LPGPPGP G  GS GI G  GP+G PGP G  G    G
Sbjct: 1131 GDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK--EG 1188

Query: 734  QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              G  G  G  G +G  GE G  G PG+ G  GP G  G
Sbjct: 1189 NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  437 bits (1123), Expect = e-122
 Identities = 271/604 (44%), Positives = 320/604 (52%), Gaps = 82/604 (13%)

Query: 245  GDPGDPGPPGTHGNPGIKGERG---PKGNPGNAQK----GEAGERGPGGIPGYKGDKGER 297
            G+PG PG  G  GNPG++G  G   P G PG   +    G  G RG  G  G  G KG  
Sbjct: 564  GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
            G+ GKPG  G+ G PG  G  G  G  G +GP G PG  G +G +G PGP G  G PG P
Sbjct: 624  GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 358  GI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGV---PGERGLPGEGFPGPKG 412
            G  G+ G  G++G  G PGA GP+G  GE G PG RG  G+   PGE+G+ G    GP G
Sbjct: 684  GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGH--GPDG 741

Query: 413  EKGSEGP------TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGI 459
             KGS GP      TGP GLQG+   GE+G  G  GP+G  G  G        G+ G +G+
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMP--GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799

Query: 460  QGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGS 508
             GP+GPPGP GP G+          G PGS+G  G  G  GP G VG  G QGP G+PG 
Sbjct: 800  PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859

Query: 509  IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGN 561
             G PG+PG  G+ G+ G +G AG PG  GP G PG       +G PG  G  G  G  G 
Sbjct: 860  KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGP 919

Query: 562  QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG---PGIPGFKGEPGLSIR- 617
             G  G PGP GP GEPG  GP G+ G   PG  G  GDRG    PG PG KG+PG   + 
Sbjct: 920  PGPAGAPGPAGPLGEPGKEGPPGLRGD--PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977

Query: 618  ------GPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEP 669
                  GP G  G RG VG PG +G+ G PG+PGP G PG  GP G  G  G  G  G P
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 670  GVRGP---PGPSGPRG----------VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQ 715
            G  GP   PGP GP G          VG +G +GD G  GLPG  G PG  G  G  G+ 
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097

Query: 716  GPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768
            G +G PG +G +G        GLPG +G  G++GD G +GD+G+ G  G  G QGL GP 
Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157

Query: 769  GDLG 772
            G  G
Sbjct: 1158 GPNG 1161



 Score =  436 bits (1120), Expect = e-122
 Identities = 275/663 (41%), Positives = 314/663 (47%), Gaps = 137/663 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGECG 301
            G  G PG PG  G  G  G +GP G+PG +  G  G  GP G PG +G  G    RG+ G
Sbjct: 411  GPVGSPGLPGAIGTDGTPGAKGPTGSPGTS--GPPGSAGPPGSPGPQGSTGPQGIRGQPG 468

Query: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG--- 358
             PG+ G KG  GP G  GP GIQG  GPPG+ G +G +G+ G  GPPGP G  GAPG   
Sbjct: 469  DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528

Query: 359  -------------------IGQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPR---G 392
                               +G  G KG +G  GRPG PG  G     G PG  GP    G
Sbjct: 529  FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588

Query: 393  PEGVPGERGLPGE-------------GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIG 438
            P G PGE G PG              G PGPKG  G  G  G  G  G+   +G  G  G
Sbjct: 589  PLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648

Query: 439  PVGPQGPMGIPGI-GSQGEQGIQGPI------GPPGPQG----PAGQGLPGSKGEVGQMG 487
             VGP GP+G PG+ G +GEQG  GP       GPPGP G    P  QG+PG  G VG +G
Sbjct: 649  EVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708

Query: 488  PTGPRG-------------------PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
            P G RG                     G G  GPKG PG  G PG  G PG  G  G++G
Sbjct: 709  PRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERG 768

Query: 529  EAGLPGAR------------------------GPEGPPG-------KGQPGPKGDEGKKG 557
             AG PG +                        GP GPPG       KG+PGP+G  G  G
Sbjct: 769  IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828

Query: 558  SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG--- 613
            S+GN G RG  GP G  G  G  GP G PG    PG PG KGD G PG  G  G PG   
Sbjct: 829  SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888

Query: 614  -LSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPG 670
               + G KG +G +GP GA G  G  G  G PGP G PGP GP+G  G  G  G +G+PG
Sbjct: 889  PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPG 948

Query: 671  VRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQG 719
              G  G  GP G  G  G KGD G+ G PGP GPPG           G  G +GE+G  G
Sbjct: 949  SHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPG 1008

Query: 720  FPGPKGTMG----------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769
             PGP GT G           G PG  G  G  G VG+ G +G  G  G+PG+ G  G +G
Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068

Query: 770  DLG 772
            D G
Sbjct: 1069 DRG 1071



 Score =  431 bits (1108), Expect = e-120
 Identities = 272/596 (45%), Positives = 312/596 (52%), Gaps = 77/596 (12%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG PGP G+ G  GI+G+ G  G PG   KGEAG +G  G  G +G  G  GE GK G
Sbjct: 447  GPPGSPGPQGSTGPQGIRGQPGDPGVPGF--KGEAGPKGEPGPHGIQGPIGPPGEEGKRG 504

Query: 305  IKGDKGSPGPYGPKGPRGIQGITGPPGD---PGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360
             +GD G+ GP GP G RG  G  G PG    PGPKG QG +G  G  GP GS G PG  G
Sbjct: 505  PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564

Query: 361  QQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415
            + G+ G RG  G PG  GP G    +G PG+ G  GP G  G RG PG  G PGPKG  G
Sbjct: 565  EPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSG 624

Query: 416  SEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIG------PPG 467
              G  G  G  G+   +G  G  G VGP GP+G PG+ G +GEQG  GP G      PPG
Sbjct: 625  DPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684

Query: 468  PQG----PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523
            P G    P  QG+PG  G VG +GP G RG       G +GEPG  GLPG+ G+ G  G 
Sbjct: 685  PPGEGGKPGDQGVPGDPGAVGPLGPRGERGN-----PGERGEPGITGLPGEKGMAGGHGP 739

Query: 524  AGKKGEAGLPGARGPEGPPG----------KGQPGPKGD------EGKKGSKGNQGQRGL 567
             G KG  G  G  G  GPPG           G PGPKGD      +G +G+ GN G RGL
Sbjct: 740  DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799

Query: 568  PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRG 627
            PGP GP   PG  GP G  G   PGP G  G  G  G PG +GE G +  G  G  GP+G
Sbjct: 800  PGPLGP---PGPAGPTGEKGE--PGPRGLVGPPGSRGNPGSRGENGPT--GAVGFAGPQG 852

Query: 628  PVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPG 670
            P G PG+KG+       G  G PGP+GL G PGP G  GV          G  GA G PG
Sbjct: 853  PDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG 912

Query: 671  VRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG 728
              G  GP GP G  G  GP G+ G++G PG  G PG +G  G +G  GP G PG KG  G
Sbjct: 913  SAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972

Query: 729  H-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
                    G PG  G  G+RG VG  G +GE G PG PG  G  G  G  G T ++
Sbjct: 973  EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028



 Score =  424 bits (1090), Expect = e-118
 Identities = 266/609 (43%), Positives = 309/609 (50%), Gaps = 87/609 (14%)

Query: 245 GDPGDPGPPGTHGNPGIKG-------------ERGPKGNPGNAQKGEAGERGPGGIPGYK 291
           G PG PGPPG   +PG  G             E+   G+      G  G  GP G  G +
Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227

Query: 292 GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
           G +G  G  G PG  GD G  GP G +GP G  G  G  G+PG  G  G  G  G PG  
Sbjct: 228 GQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGAR 287

Query: 352 GSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP 403
           G PGAPG+       G +G++G +G+ G PG+ G  G  G  G  GP GP G+PGERG  
Sbjct: 288 GFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRL 347

Query: 404 G-EGFPGPKGE---KGSEGPTGPQGLQGLS-------IKGEKGDIGPVGPQGPMGIPGIG 452
           G +G PG +G     G  GP GP G+ G S       +KGE G  G  GP+GP      G
Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQ-----G 402

Query: 453 SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPG 507
            +GE G  GP+G PG  G  G  G PG+KG  G  G +GP G  G     G QG  G  G
Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462

Query: 508 SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRG 566
             G PG PGVPG  G AG KGE G  G +GP GPPG +G+ GP+GD G  G  G  G+RG
Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522

Query: 567 LPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQG 624
            PG  G  G  G+ GP G  G   P G  GPKG +G PG PG  G PG   + G  GVQG
Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582

Query: 625 PR---GPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG----------VGDTGAKGEPGV 671
           P    GP+GAPG   DG PG PG  G+ G PG MGL G           G+ G  G PG 
Sbjct: 583 PEGKLGPLGAPG--EDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640

Query: 672 RGPP------GPSGPRGV-------GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGE 714
           RG P      GPSGP G        G QGP G TG +GLPGPPGPPG     G QG+ G+
Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGD 700

Query: 715 QGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGL 764
            G  G  GP+G  G+          GLPG+KG  G  G  G KG  G  G PG  G  GL
Sbjct: 701 PGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGL 760

Query: 765 QGPKGDLGL 773
           QG  G+ G+
Sbjct: 761 QGMPGERGI 769



 Score =  240 bits (613), Expect = 5e-63
 Identities = 144/304 (47%), Positives = 165/304 (54%), Gaps = 28/304 (9%)

Query: 245  GDPGDPGPPGTHGNPGIKG---ERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGER 297
            G+PG  GPPG  G+PG  G   +RGP G PG        GE G+ GP G PG  G  G+R
Sbjct: 933  GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992

Query: 298  GECGKPGIKGDKGSPGPYGPKG------PRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
            G  G PG +G++G PG  GP G      P G  G  GPPG  GP G  G  GEPGP GP 
Sbjct: 993  GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----G 406
            G+ G PG  + G  GERG  G PG  G P   G PG PGP G  G  G+RG PG     G
Sbjct: 1053 GNDGTPG--RDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG 1110

Query: 407  FPGPKGEKGSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQG 461
             PG  G++G  GP GP+G +G       +G+KG  G  G QG  G PG  G QG  GI G
Sbjct: 1111 PPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPG 1170

Query: 462  PIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGE 520
            P GP GP GP G  G  G+ G +G +GP G RG VG    GP+G PG  G PG PG PG 
Sbjct: 1171 PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEA--GPEGPPGEPGPPGPPGPPGH 1228

Query: 521  DGAA 524
              AA
Sbjct: 1229 LTAA 1232



 Score =  232 bits (591), Expect = 2e-60
 Identities = 163/389 (41%), Positives = 195/389 (50%), Gaps = 45/389 (11%)

Query: 416 SEGPTGPQGLQGLSIKGEKGDIGPV-------GPQGPMGIPGIGSQGEQGIQGPIGPPGP 468
           S+ P G     G   KG+KG+ G V       G  GP G PG  SQG +G +GP G PGP
Sbjct: 97  SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPG--SQGPRGERGPKGRPGP 154

Query: 469 QGPAG-QGLPGSKGEVGQMGPTG-PRGPVGIGVQGP-----KGEPGSIGLPGQPGV-PGE 520
           +GP G  G PG  G+ G  GP G P  P   G+  P      G     GL  Q G+ PG 
Sbjct: 155 RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGS 214

Query: 521 DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580
            G  G +G  GL G +G  GP G   PG  GD G  G  G++G  G PG  G  GEPG  
Sbjct: 215 VGPVGPRGPQGLQGQQGGAGPTGP--PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRN 272

Query: 581 GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP 640
           G  G  G +  G PG +G  G PG+PG KG      RG KG++GP+G VGAPG KG+  P
Sbjct: 273 GNPGEVGFA--GSPGARGFPGAPGLPGLKGH-----RGHKGLEGPKGEVGAPGSKGEAGP 325

Query: 641 GVP-------GPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDT 692
             P       GPRG+PG  G +G +G    G +G  G+ G PGP GP G+ G+ G  G+ 
Sbjct: 326 TGPMGAMGPLGPRGMPGERGRLGPQGA--PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP 383

Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKG 751
           G KG  GP G  G  G QG +GE GP   PGP G+     PG  G  G  G  G KG  G
Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGP---PGPVGS-----PGLPGAIGTDGTPGAKGPTG 435

Query: 752 EIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
             G  G PG  G  G  G  G T  + I+
Sbjct: 436 SPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 8/50 (16%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGY 290
            E   G  G  GPPG  G+    GE GP+G P     GE G  GP G PG+
Sbjct: 1187 EGNPGPLGPIGPPGVRGS---VGEAGPEGPP-----GEPGPPGPPGPPGH 1228


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  442 bits (1138), Expect = e-124
 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG  G  G  G  G +G RGP G PG   KG +G  GP G PG +G +G +G  G PG
Sbjct: 886  GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 943

Query: 305  IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
             KG  G PG  G       +G  G QG TGPPG  G  G QG  GE GP G  G PG PG
Sbjct: 944  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003

Query: 359  I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416
              G+QG+ G  G+EG  G PGP G+   G+ GP G  G PGERGLPG +G PG KG +G 
Sbjct: 1004 PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061

Query: 417  EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462
            +GP GP G  G          + + G  G  GP GP G  G PG     G  G  G+QGP
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 463  IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512
            +G PGP GPAG           G PG KG  G  G  GP GP G+  QGP G PG  G  
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1179

Query: 513  GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571
            G+PG  G+ G  G+KG+ G  G  GP GP G +G PGP G++G+ G  G  G  G PGP 
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239

Query: 572  GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603
            GP+G  G  GP G PG+                  PGPPG      PKG+RG     GP 
Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299

Query: 604  ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641
               G PG KG PG    GPKG  GP             GP G  G+ GD       G PG
Sbjct: 1300 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1357

Query: 642  VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682
             PGP G  GPPGP G RG           G+ GAKGE G  GPPG +GP G         
Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1417

Query: 683  ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725
                      VG QG  G  GQ G PGP GPPG        GS+G KG  G  G  GP G
Sbjct: 1418 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1477

Query: 726  TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
              G     GLPG +G  G +GD G  G  G +G PG PG  G QGPKG+ G T
Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530



 Score =  440 bits (1132), Expect = e-123
 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E GDPG  GP G  G PG  G+ G +G P     G  G RG  G PG KGD+G  G  G 
Sbjct: 566  ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 620

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358
            PG KG +G  GP GP GP G  G+ G  G+ GP+G  G  G  G  GP G+PGAPG    
Sbjct: 621  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680

Query: 359  ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414
                G  G KG  G +G PG PG  G  G  G PGP+GP G PGE+G   +G PG  G  
Sbjct: 681  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 738

Query: 415  GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473
            G++GP G  G +G S  GEKG +GP GPQGP+G PG  G +G  G++G  G  G +G  G
Sbjct: 739  GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796

Query: 474  -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516
                    GL G +GEVGQ+GP G  GP G           G  G  GE G +G+PG PG
Sbjct: 797  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 856

Query: 517  VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
             PG  G  G  G  G PGA G +G  G  G+PGP+G  G  G +G++G RG  G  GPKG
Sbjct: 857  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916

Query: 576  EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618
              G  GP G PG   P             GPPGP G  G PG PG +GE G   +    G
Sbjct: 917  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976

Query: 619  PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656
            P GV GP+GP G  G  G+ G+PG                      PGP+G+ G  GP G
Sbjct: 977  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036

Query: 657  LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705
            LRG     G  GA+G PG++G  GP GP G VG+ G +G  G        G PGP GPPG
Sbjct: 1037 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1096

Query: 706  -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752
              G +G  GE+GPQ            G PGP G  G   PG+ G+ GE G+ G+KG KG+
Sbjct: 1097 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1154

Query: 753  IGEPGSPGKQGLQGPKGDLGL 773
             GE G PG  GLQGP G  G+
Sbjct: 1155 KGENGPPGPPGLQGPVGAPGI 1175



 Score =  437 bits (1125), Expect = e-122
 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299
            E  KG  G  G PG  G  G KG+ G  G PG   ++G  G  G  G PG  G+KG RG 
Sbjct: 825  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884

Query: 300  CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347
             GKPG +G +G  GP             GPKG  G  G  GPPG+ GP+G QG  G PGP
Sbjct: 885  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944

Query: 348  PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393
             GP G PG  G+ G  G +GE G +G+ G PGP GV             GE G PGP GP
Sbjct: 945  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 1004

Query: 394  EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439
               PGE+GLPG       +G PGP+G  G +GP G +G  G           G KG  GP
Sbjct: 1005 ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061

Query: 440  VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494
             GP GP+G PG     G+ G  G+ G  GP GP GPAG+ G PG KG  G  G  G +GP
Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 495  VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553
            VG+ G  GP G PG  G  G+ G PG+ G+ G KGE G PG  G +GP   G PG  G +
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1179

Query: 554  GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
            G+ G +G QG  G  G EG +G PG  GP G+ G  +PGPPG KG+ G  G  G  G PG
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1237

Query: 614  -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668
                +GP G  GP+GP G+ G + G G  G PG  G PGPPG  G+ G  G+ G KGE  
Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1297

Query: 669  -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720
             PG  GPPG  GP   G  GPKG+ G  G PG PGPPG        G  G KGE G  G 
Sbjct: 1298 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355

Query: 721  PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            PGP G  G     G PG++   G  G  G  G+KG KGE G  G PGK G  GP+G  G
Sbjct: 1356 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1414



 Score =  436 bits (1121), Expect = e-122
 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG   +G +G+ GP G+ G+ G++G  G  G 
Sbjct: 995  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1052

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362
            PG+KG +G   P GP GP G  G  G  G  GP G  G  G  GPPGP G  GAPG    
Sbjct: 1053 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1106

Query: 363  GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418
              KG +G  GR G  GP+G+     PGP GP G PGE G  GE    G  G KG+KG  G
Sbjct: 1107 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 419  PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476
            P GP GLQG +   G  G  G  GP+G  G+   G +G++G +G  GPPGP G  G  G 
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1217

Query: 477  PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
            PG KGE G +GP GP GP G           G QGP G  GS+G  G+ G PGE G  G 
Sbjct: 1218 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1277

Query: 527  KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
             GEAG+ G +G  G      PPG  G PG KG  G  G KGN G  G PG  GP GEPG 
Sbjct: 1278 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1337

Query: 580  MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632
             G  G+ G          PGPPGP G+ G PG PG +G PG +  G +G QG +G  G  
Sbjct: 1338 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1395

Query: 633  GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683
            G +G  G  G  GP+G  G PGP GLRG    VG+ G  G  G  GPPGP GP G+    
Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455

Query: 684  ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729
               G++G KG  G  GL GPPG  G        G+QG  G +G  G PGP G +G     
Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766
            GLPG +G  G +G  G  G KG+ G PG PG  G  G
Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  435 bits (1118), Expect = e-121
 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300
            G PG  GPPG  G  G  GE+G  G PG        G  G +G  G+ G KG KGE+GE 
Sbjct: 736  GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 795

Query: 301  GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344
            G PG KGD G  G         P G  GP G +G  GP GDPGP G  G KG+       
Sbjct: 796  GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855

Query: 345  --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400
              PG  GP GS G PG  G  G KG RG  G+PG  G  G  G  G  G RGP G PG +
Sbjct: 856  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 915

Query: 401  GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443
            G  G +G PGP GE+G +GP GP G  G                   +GE G  G  GP 
Sbjct: 916  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 975

Query: 444  GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493
            GP G+  +G QG  G  GPIG    PGP GP G QGLPG+ G+ G  G  GP+G      
Sbjct: 976  GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1033

Query: 494  PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
            P G+             G  G KG  G  G PG  G PGE G+AG  G  GLPG  GP+G
Sbjct: 1034 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093

Query: 541  PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587
            PPG    KG PG KG +G  G  G QG  GLPGP GP G PG     G  G PG      
Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153

Query: 588  ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633
                   PGPPG +G  G PGI G  GEPG              G +G  GP GP+G  G
Sbjct: 1154 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1213

Query: 634  LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673
            L G     G  G  GP G PGPPGP G +G                VG  G KGEPG  G
Sbjct: 1214 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1273

Query: 674  PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726
             PGP G  GVG  GPKG+ G+KG  GPPG   PPG     G  G KG  GP GFPG  G 
Sbjct: 1274 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331

Query: 727  MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779
             G        G+ G KGE G+ G  G  G  GE G PG PGK+G  G  G  G   E+  
Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391

Query: 780  KLITEICGCGPKCKETPL 797
            K   E    GP  K  P+
Sbjct: 1392 K--GEAGAEGPPGKTGPV 1407



 Score =  433 bits (1113), Expect = e-121
 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289
            E+G  G PGPPG  G  G  GE GP+G PG A               G+ G  G  G PG
Sbjct: 629  ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688

Query: 290  YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334
             KG+ G +GE G PG +G+   +G PGP GP GP             G+ G  GPPG PG
Sbjct: 689  PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 748

Query: 335  PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382
             +G  G KG  GPPGP G  G PG           G +G KGE+G++G PG  G +G+  
Sbjct: 749  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 808

Query: 383  --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405
              GE GQ GPRG +                           GVPG  G PG         
Sbjct: 809  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 868

Query: 406  --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450
              GFPG  GEKG+             GPTGP+G +G   +G  G  GP G  G  G PG 
Sbjct: 869  FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 926

Query: 451  IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502
             G +G QG QGP+G PGP+GP G        G PG +GE G  G TGP GP G +G QGP
Sbjct: 927  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986

Query: 503  KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558
             GE G IG  G PG PG  G  G  G AG  GA+G  GP G  G+ GP   +G  G++G 
Sbjct: 987  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046

Query: 559  KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605
             G QG  GL G EGP+G P            G  GP G+PG   P GPPGP G++G PG 
Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106

Query: 606  PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657
             G +G  G   ++GP G+ GP GP G+PG  GD       G  G  G +G  GPPGP GL
Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166

Query: 658  RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709
            +     G  G PG+ G  G  GPRG  G  G KGD G +G PGPPGP G        G +
Sbjct: 1167 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221

Query: 710  GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
            G  G+ GP G PGP G  G        G  G  G  G  G VG+KG+ GE G PG PG+ 
Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1281

Query: 763  GLQGPKGDLG 772
            G+ GPKG+ G
Sbjct: 1282 GVGGPKGERG 1291



 Score =  421 bits (1083), Expect = e-117
 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291
            +G PG  GP G  G PG++G  GP G+PG+    G  G  G  G+PG           Y 
Sbjct: 453  EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 512

Query: 292  GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317
            GD                                   G  G  G PG  G KG  G  GP
Sbjct: 513  GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 572

Query: 318  KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370
            +GPRG+QG  GP G PG +      G +G  GEPG  G  G  G PG+ G +G +GERG 
Sbjct: 573  QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 632

Query: 371  EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413
            +G PG PG  G+          G PG+ GPR   GP G PG  G PG    +G PGPKG 
Sbjct: 633  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692

Query: 414  KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473
             G +G  GP G Q     G  G  G  GPQGP+G P  G +G QG  G  G PG  GP G
Sbjct: 693  MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 745

Query: 474  Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531
              G  G  GE G +GP GP+GP+G  G +G KG  G  GL G  G  GEDG  G KG+ G
Sbjct: 746  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805

Query: 532  LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591
            L G RG       GQ GP+G++G +G KG  G  G PGP G  GE G +G  G+PG   P
Sbjct: 806  LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 858

Query: 592  GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635
            G  GPKG  G PG PG  GE G                 GP+G +G RGP G PG K   
Sbjct: 859  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918

Query: 636  -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681
             GDG PG PG RG  GP GP+G  G              G  G +GE G +G  GP GP 
Sbjct: 919  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978

Query: 682  G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729
            G VG QGP G+T   G++G PGPPGPPG        G +G KG+ GPQG  G  G  G  
Sbjct: 979  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1038

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773
            G PG++G  G +G  G KG +G  G P   GSPG++G  G  G +GL
Sbjct: 1039 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085



 Score =  308 bits (788), Expect = 2e-83
 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%)

Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384
           PP     PG P         I   G  GE+GQ+G P          G PGP G    +G 
Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 467

Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444
           PG  GP GP G PG+RG PG   PG  G  G  GP G   +      G+ G  GP     
Sbjct: 468 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 524

Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503
                 I  Q    ++GP GP G  G P   G PGS G  G+ G  GP+GP G  VQGP 
Sbjct: 525 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 581

Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563
             PG  G PG+ G PG DG  G  GE G  G RG +G PG       GD+G +G +G QG
Sbjct: 582 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 634

Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622
             G PG +G +GE G +GP G+PG + P G  GP+G  G PG PG  G  G    GPKG 
Sbjct: 635 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 692

Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682
            GP+G  G PG +G+     PGP+GLPGP GP+G    G+ G +G+PG+ G PG  GP G
Sbjct: 693 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 745

Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738
               G +G +G+KG  GPPGP           QGP G+PGP+G  G     GL G KGE 
Sbjct: 746 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 792

Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           GE      +GD+G KGD+GE+G+ G  G+ G +GPKG  G T
Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 834



 Score =  260 bits (664), Expect = 6e-69
 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296
            EKG+ GD      PGPPG  G  G  G  GP+G PG+   G  G  G  G PG  G+ G 
Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1277

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
             GE G  G KG++G  G  GP G  G  G  GPPGD GPKG  G  G PG PGP G PG 
Sbjct: 1278 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1337

Query: 357  PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414
             G  Q G+ G++G++G PG PGP G  GE G PGP G  G PG  G  G +G  G KGE 
Sbjct: 1338 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395

Query: 415  GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451
            G+EGP G               P+GL+G+        + G  G  GP GP GP G+PG+ 
Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455

Query: 452  ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504
                  G +G  G+ G IGPPG QG  G +GLPG++G  G  G  G  GP G    GP G
Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1513

Query: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544
             PG  G  G  G  G  G AG+KG++GLPG  G  GPPG+
Sbjct: 1514 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553



 Score =  204 bits (520), Expect = 3e-52
 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%)

Query: 243  EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
            EKG+PG+   PGPPG  G  G KGERG KG  G    G AG  G  G PG  G KG  G 
Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1322

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             G PG  G  G PGP G  G  G +G  G PG PGP G  G  G PGPPG  G PGA G 
Sbjct: 1323 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1382

Query: 360  ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405
                G++G KGE G EG PG  GP+G  G  G+PGP G  G+PG   E+GLPG       
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1442

Query: 406  -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436
                   G PG KG+ GS+G  G  GL GL      +GEKGD                  
Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502

Query: 437  ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477
                GP+GP GP G+PG              G +G+ G+ GP G PGP G   Q LP
Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559



 Score =  149 bits (375), Expect = 2e-35
 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%)

Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597
           P  PP + + GP        ++ +    G  G +G KGEP ++ P    G  + GPPGP 
Sbjct: 405 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 459

Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656
           G  G              I GP G+QGP GP G PG +G  G PG+PG  GLPGPPG M 
Sbjct: 460 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 505

Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696
           +     G  G+KG                    +RGPPGP G  G  G  G  G +G KG
Sbjct: 506 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565

Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743
             G PGP G   +G++G  GP G PG +G  G     G+PG+ G  G+R         GD
Sbjct: 566 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623

Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G +G++G  G PG PG  G++G  G++G
Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 652



 Score =  105 bits (263), Expect = 2e-22
 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%)

Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647
           P  P  +  GPG+P        SI G  G  G +G  G P     G+  +G PG  GP G
Sbjct: 405 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 463

Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702
           + GPPG  G      TG  G+PG RGPPG  G  G             GLPGPPG     
Sbjct: 464 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 507

Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741
           P  YG  G KG                     +G PGP G  G     G PG  G  GE 
Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 567

Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776
           GD G +G +G  G PG    PGK+G  G  G  G+  E
Sbjct: 568 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 605


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  442 bits (1138), Expect = e-124
 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG  G  G  G  G +G RGP G PG   KG +G  GP G PG +G +G +G  G PG
Sbjct: 835  GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 892

Query: 305  IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
             KG  G PG  G       +G  G QG TGPPG  G  G QG  GE GP G  G PG PG
Sbjct: 893  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952

Query: 359  I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416
              G+QG+ G  G+EG  G PGP G+   G+ GP G  G PGERGLPG +G PG KG +G 
Sbjct: 953  PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010

Query: 417  EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462
            +GP GP G  G          + + G  G  GP GP G  G PG     G  G  G+QGP
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 463  IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512
            +G PGP GPAG           G PG KG  G  G  GP GP G+  QGP G PG  G  
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1128

Query: 513  GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571
            G+PG  G+ G  G+KG+ G  G  GP GP G +G PGP G++G+ G  G  G  G PGP 
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188

Query: 572  GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603
            GP+G  G  GP G PG+                  PGPPG      PKG+RG     GP 
Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248

Query: 604  ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641
               G PG KG PG    GPKG  GP             GP G  G+ GD       G PG
Sbjct: 1249 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1306

Query: 642  VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682
             PGP G  GPPGP G RG           G+ GAKGE G  GPPG +GP G         
Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366

Query: 683  ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725
                      VG QG  G  GQ G PGP GPPG        GS+G KG  G  G  GP G
Sbjct: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1426

Query: 726  TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
              G     GLPG +G  G +GD G  G  G +G PG PG  G QGPKG+ G T
Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479



 Score =  440 bits (1132), Expect = e-123
 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E GDPG  GP G  G PG  G+ G +G P     G  G RG  G PG KGD+G  G  G 
Sbjct: 515  ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 569

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358
            PG KG +G  GP GP GP G  G+ G  G+ GP+G  G  G  G  GP G+PGAPG    
Sbjct: 570  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629

Query: 359  ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414
                G  G KG  G +G PG PG  G  G  G PGP+GP G PGE+G   +G PG  G  
Sbjct: 630  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 687

Query: 415  GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473
            G++GP G  G +G S  GEKG +GP GPQGP+G PG  G +G  G++G  G  G +G  G
Sbjct: 688  GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745

Query: 474  -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516
                    GL G +GEVGQ+GP G  GP G           G  G  GE G +G+PG PG
Sbjct: 746  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 805

Query: 517  VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
             PG  G  G  G  G PGA G +G  G  G+PGP+G  G  G +G++G RG  G  GPKG
Sbjct: 806  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865

Query: 576  EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618
              G  GP G PG   P             GPPGP G  G PG PG +GE G   +    G
Sbjct: 866  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925

Query: 619  PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656
            P GV GP+GP G  G  G+ G+PG                      PGP+G+ G  GP G
Sbjct: 926  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985

Query: 657  LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705
            LRG     G  GA+G PG++G  GP GP G VG+ G +G  G        G PGP GPPG
Sbjct: 986  LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1045

Query: 706  -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752
              G +G  GE+GPQ            G PGP G  G   PG+ G+ GE G+ G+KG KG+
Sbjct: 1046 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1103

Query: 753  IGEPGSPGKQGLQGPKGDLGL 773
             GE G PG  GLQGP G  G+
Sbjct: 1104 KGENGPPGPPGLQGPVGAPGI 1124



 Score =  437 bits (1125), Expect = e-122
 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299
            E  KG  G  G PG  G  G KG+ G  G PG   ++G  G  G  G PG  G+KG RG 
Sbjct: 774  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833

Query: 300  CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347
             GKPG +G +G  GP             GPKG  G  G  GPPG+ GP+G QG  G PGP
Sbjct: 834  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893

Query: 348  PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393
             GP G PG  G+ G  G +GE G +G+ G PGP GV             GE G PGP GP
Sbjct: 894  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 953

Query: 394  EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439
               PGE+GLPG       +G PGP+G  G +GP G +G  G           G KG  GP
Sbjct: 954  ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010

Query: 440  VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494
             GP GP+G PG     G+ G  G+ G  GP GP GPAG+ G PG KG  G  G  G +GP
Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 495  VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553
            VG+ G  GP G PG  G  G+ G PG+ G+ G KGE G PG  G +GP   G PG  G +
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1128

Query: 554  GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
            G+ G +G QG  G  G EG +G PG  GP G+ G  +PGPPG KG+ G  G  G  G PG
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1186

Query: 614  -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668
                +GP G  GP+GP G+ G + G G  G PG  G PGPPG  G+ G  G+ G KGE  
Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1246

Query: 669  -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720
             PG  GPPG  GP   G  GPKG+ G  G PG PGPPG        G  G KGE G  G 
Sbjct: 1247 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304

Query: 721  PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            PGP G  G     G PG++   G  G  G  G+KG KGE G  G PGK G  GP+G  G
Sbjct: 1305 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1363



 Score =  436 bits (1121), Expect = e-122
 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG   +G +G+ GP G+ G+ G++G  G  G 
Sbjct: 944  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1001

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362
            PG+KG +G   P GP GP G  G  G  G  GP G  G  G  GPPGP G  GAPG    
Sbjct: 1002 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1055

Query: 363  GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418
              KG +G  GR G  GP+G+     PGP GP G PGE G  GE    G  G KG+KG  G
Sbjct: 1056 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108

Query: 419  PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476
            P GP GLQG +   G  G  G  GP+G  G+   G +G++G +G  GPPGP G  G  G 
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1166

Query: 477  PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
            PG KGE G +GP GP GP G           G QGP G  GS+G  G+ G PGE G  G 
Sbjct: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1226

Query: 527  KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
             GEAG+ G +G  G      PPG  G PG KG  G  G KGN G  G PG  GP GEPG 
Sbjct: 1227 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1286

Query: 580  MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632
             G  G+ G          PGPPGP G+ G PG PG +G PG +  G +G QG +G  G  
Sbjct: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1344

Query: 633  GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683
            G +G  G  G  GP+G  G PGP GLRG    VG+ G  G  G  GPPGP GP G+    
Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404

Query: 684  ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729
               G++G KG  G  GL GPPG  G        G+QG  G +G  G PGP G +G     
Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766
            GLPG +G  G +G  G  G KG+ G PG PG  G  G
Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  435 bits (1118), Expect = e-121
 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300
            G PG  GPPG  G  G  GE+G  G PG        G  G +G  G+ G KG KGE+GE 
Sbjct: 685  GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 744

Query: 301  GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344
            G PG KGD G  G         P G  GP G +G  GP GDPGP G  G KG+       
Sbjct: 745  GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804

Query: 345  --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400
              PG  GP GS G PG  G  G KG RG  G+PG  G  G  G  G  G RGP G PG +
Sbjct: 805  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 864

Query: 401  GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443
            G  G +G PGP GE+G +GP GP G  G                   +GE G  G  GP 
Sbjct: 865  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 924

Query: 444  GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493
            GP G+  +G QG  G  GPIG    PGP GP G QGLPG+ G+ G  G  GP+G      
Sbjct: 925  GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982

Query: 494  PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
            P G+             G  G KG  G  G PG  G PGE G+AG  G  GLPG  GP+G
Sbjct: 983  PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042

Query: 541  PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587
            PPG    KG PG KG +G  G  G QG  GLPGP GP G PG     G  G PG      
Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102

Query: 588  ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633
                   PGPPG +G  G PGI G  GEPG              G +G  GP GP+G  G
Sbjct: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1162

Query: 634  LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673
            L G     G  G  GP G PGPPGP G +G                VG  G KGEPG  G
Sbjct: 1163 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1222

Query: 674  PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726
             PGP G  GVG  GPKG+ G+KG  GPPG   PPG     G  G KG  GP GFPG  G 
Sbjct: 1223 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280

Query: 727  MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779
             G        G+ G KGE G+ G  G  G  GE G PG PGK+G  G  G  G   E+  
Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340

Query: 780  KLITEICGCGPKCKETPL 797
            K   E    GP  K  P+
Sbjct: 1341 K--GEAGAEGPPGKTGPV 1356



 Score =  433 bits (1113), Expect = e-121
 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289
            E+G  G PGPPG  G  G  GE GP+G PG A               G+ G  G  G PG
Sbjct: 578  ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637

Query: 290  YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334
             KG+ G +GE G PG +G+   +G PGP GP GP             G+ G  GPPG PG
Sbjct: 638  PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 697

Query: 335  PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382
             +G  G KG  GPPGP G  G PG           G +G KGE+G++G PG  G +G+  
Sbjct: 698  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 757

Query: 383  --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405
              GE GQ GPRG +                           GVPG  G PG         
Sbjct: 758  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 817

Query: 406  --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450
              GFPG  GEKG+             GPTGP+G +G   +G  G  GP G  G  G PG 
Sbjct: 818  FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 875

Query: 451  IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502
             G +G QG QGP+G PGP+GP G        G PG +GE G  G TGP GP G +G QGP
Sbjct: 876  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935

Query: 503  KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558
             GE G IG  G PG PG  G  G  G AG  GA+G  GP G  G+ GP   +G  G++G 
Sbjct: 936  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995

Query: 559  KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605
             G QG  GL G EGP+G P            G  GP G+PG   P GPPGP G++G PG 
Sbjct: 996  PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055

Query: 606  PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657
             G +G  G   ++GP G+ GP GP G+PG  GD       G  G  G +G  GPPGP GL
Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115

Query: 658  RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709
            +     G  G PG+ G  G  GPRG  G  G KGD G +G PGPPGP G        G +
Sbjct: 1116 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170

Query: 710  GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
            G  G+ GP G PGP G  G        G  G  G  G  G VG+KG+ GE G PG PG+ 
Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1230

Query: 763  GLQGPKGDLG 772
            G+ GPKG+ G
Sbjct: 1231 GVGGPKGERG 1240



 Score =  421 bits (1083), Expect = e-117
 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291
            +G PG  GP G  G PG++G  GP G+PG+    G  G  G  G+PG           Y 
Sbjct: 402  EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 461

Query: 292  GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317
            GD                                   G  G  G PG  G KG  G  GP
Sbjct: 462  GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 521

Query: 318  KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370
            +GPRG+QG  GP G PG +      G +G  GEPG  G  G  G PG+ G +G +GERG 
Sbjct: 522  QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581

Query: 371  EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413
            +G PG PG  G+          G PG+ GPR   GP G PG  G PG    +G PGPKG 
Sbjct: 582  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641

Query: 414  KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473
             G +G  GP G Q     G  G  G  GPQGP+G P  G +G QG  G  G PG  GP G
Sbjct: 642  MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 694

Query: 474  Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531
              G  G  GE G +GP GP+GP+G  G +G KG  G  GL G  G  GEDG  G KG+ G
Sbjct: 695  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754

Query: 532  LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591
            L G RG       GQ GP+G++G +G KG  G  G PGP G  GE G +G  G+PG   P
Sbjct: 755  LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 807

Query: 592  GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635
            G  GPKG  G PG PG  GE G                 GP+G +G RGP G PG K   
Sbjct: 808  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867

Query: 636  -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681
             GDG PG PG RG  GP GP+G  G              G  G +GE G +G  GP GP 
Sbjct: 868  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927

Query: 682  G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729
            G VG QGP G+T   G++G PGPPGPPG        G +G KG+ GPQG  G  G  G  
Sbjct: 928  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 987

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773
            G PG++G  G +G  G KG +G  G P   GSPG++G  G  G +GL
Sbjct: 988  GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034



 Score =  308 bits (788), Expect = 2e-83
 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%)

Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384
           PP     PG P         I   G  GE+GQ+G P          G PGP G    +G 
Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416

Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444
           PG  GP GP G PG+RG PG   PG  G  G  GP G   +      G+ G  GP     
Sbjct: 417 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 473

Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503
                 I  Q    ++GP GP G  G P   G PGS G  G+ G  GP+GP G  VQGP 
Sbjct: 474 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 530

Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563
             PG  G PG+ G PG DG  G  GE G  G RG +G PG       GD+G +G +G QG
Sbjct: 531 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 583

Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622
             G PG +G +GE G +GP G+PG + P G  GP+G  G PG PG  G  G    GPKG 
Sbjct: 584 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 641

Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682
            GP+G  G PG +G+     PGP+GLPGP GP+G    G+ G +G+PG+ G PG  GP G
Sbjct: 642 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 694

Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738
               G +G +G+KG  GPPGP           QGP G+PGP+G  G     GL G KGE 
Sbjct: 695 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 741

Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           GE      +GD+G KGD+GE+G+ G  G+ G +GPKG  G T
Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 783



 Score =  260 bits (664), Expect = 6e-69
 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296
            EKG+ GD      PGPPG  G  G  G  GP+G PG+   G  G  G  G PG  G+ G 
Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1226

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
             GE G  G KG++G  G  GP G  G  G  GPPGD GPKG  G  G PG PGP G PG 
Sbjct: 1227 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1286

Query: 357  PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414
             G  Q G+ G++G++G PG PGP G  GE G PGP G  G PG  G  G +G  G KGE 
Sbjct: 1287 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344

Query: 415  GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451
            G+EGP G               P+GL+G+        + G  G  GP GP GP G+PG+ 
Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404

Query: 452  ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504
                  G +G  G+ G IGPPG QG  G +GLPG++G  G  G  G  GP G    GP G
Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1462

Query: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544
             PG  G  G  G  G  G AG+KG++GLPG  G  GPPG+
Sbjct: 1463 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502



 Score =  204 bits (520), Expect = 3e-52
 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%)

Query: 243  EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
            EKG+PG+   PGPPG  G  G KGERG KG  G    G AG  G  G PG  G KG  G 
Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1271

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             G PG  G  G PGP G  G  G +G  G PG PGP G  G  G PGPPG  G PGA G 
Sbjct: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1331

Query: 360  ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405
                G++G KGE G EG PG  GP+G  G  G+PGP G  G+PG   E+GLPG       
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1391

Query: 406  -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436
                   G PG KG+ GS+G  G  GL GL      +GEKGD                  
Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451

Query: 437  ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477
                GP+GP GP G+PG              G +G+ G+ GP G PGP G   Q LP
Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508



 Score =  149 bits (375), Expect = 2e-35
 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%)

Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597
           P  PP + + GP        ++ +    G  G +G KGEP ++ P    G  + GPPGP 
Sbjct: 354 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 408

Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656
           G  G              I GP G+QGP GP G PG +G  G PG+PG  GLPGPPG M 
Sbjct: 409 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 454

Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696
           +     G  G+KG                    +RGPPGP G  G  G  G  G +G KG
Sbjct: 455 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514

Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743
             G PGP G   +G++G  GP G PG +G  G     G+PG+ G  G+R         GD
Sbjct: 515 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572

Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G +G++G  G PG PG  G++G  G++G
Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 601



 Score =  105 bits (263), Expect = 2e-22
 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%)

Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647
           P  P  +  GPG+P        SI G  G  G +G  G P     G+  +G PG  GP G
Sbjct: 354 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 412

Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702
           + GPPG  G      TG  G+PG RGPPG  G  G             GLPGPPG     
Sbjct: 413 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 456

Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741
           P  YG  G KG                     +G PGP G  G     G PG  G  GE 
Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 516

Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776
           GD G +G +G  G PG    PGK+G  G  G  G+  E
Sbjct: 517 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 554


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  442 bits (1138), Expect = e-124
 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG  G  G  G  G +G RGP G PG   KG +G  GP G PG +G +G +G  G PG
Sbjct: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 931

Query: 305  IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
             KG  G PG  G       +G  G QG TGPPG  G  G QG  GE GP G  G PG PG
Sbjct: 932  PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991

Query: 359  I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416
              G+QG+ G  G+EG  G PGP G+   G+ GP G  G PGERGLPG +G PG KG +G 
Sbjct: 992  PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049

Query: 417  EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462
            +GP GP G  G          + + G  G  GP GP G  G PG     G  G  G+QGP
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 463  IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512
            +G PGP GPAG           G PG KG  G  G  GP GP G+  QGP G PG  G  
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1167

Query: 513  GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571
            G+PG  G+ G  G+KG+ G  G  GP GP G +G PGP G++G+ G  G  G  G PGP 
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227

Query: 572  GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603
            GP+G  G  GP G PG+                  PGPPG      PKG+RG     GP 
Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287

Query: 604  ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641
               G PG KG PG    GPKG  GP             GP G  G+ GD       G PG
Sbjct: 1288 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345

Query: 642  VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682
             PGP G  GPPGP G RG           G+ GAKGE G  GPPG +GP G         
Sbjct: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405

Query: 683  ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725
                      VG QG  G  GQ G PGP GPPG        GS+G KG  G  G  GP G
Sbjct: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465

Query: 726  TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
              G     GLPG +G  G +GD G  G  G +G PG PG  G QGPKG+ G T
Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518



 Score =  440 bits (1132), Expect = e-123
 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E GDPG  GP G  G PG  G+ G +G P     G  G RG  G PG KGD+G  G  G 
Sbjct: 554  ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 608

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358
            PG KG +G  GP GP GP G  G+ G  G+ GP+G  G  G  G  GP G+PGAPG    
Sbjct: 609  PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668

Query: 359  ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414
                G  G KG  G +G PG PG  G  G  G PGP+GP G PGE+G   +G PG  G  
Sbjct: 669  AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 726

Query: 415  GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473
            G++GP G  G +G S  GEKG +GP GPQGP+G PG  G +G  G++G  G  G +G  G
Sbjct: 727  GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784

Query: 474  -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516
                    GL G +GEVGQ+GP G  GP G           G  G  GE G +G+PG PG
Sbjct: 785  FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844

Query: 517  VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
             PG  G  G  G  G PGA G +G  G  G+PGP+G  G  G +G++G RG  G  GPKG
Sbjct: 845  YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904

Query: 576  EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618
              G  GP G PG   P             GPPGP G  G PG PG +GE G   +    G
Sbjct: 905  TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964

Query: 619  PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656
            P GV GP+GP G  G  G+ G+PG                      PGP+G+ G  GP G
Sbjct: 965  PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024

Query: 657  LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705
            LRG     G  GA+G PG++G  GP GP G VG+ G +G  G        G PGP GPPG
Sbjct: 1025 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1084

Query: 706  -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752
              G +G  GE+GPQ            G PGP G  G   PG+ G+ GE G+ G+KG KG+
Sbjct: 1085 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1142

Query: 753  IGEPGSPGKQGLQGPKGDLGL 773
             GE G PG  GLQGP G  G+
Sbjct: 1143 KGENGPPGPPGLQGPVGAPGI 1163



 Score =  437 bits (1125), Expect = e-122
 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299
            E  KG  G  G PG  G  G KG+ G  G PG   ++G  G  G  G PG  G+KG RG 
Sbjct: 813  EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872

Query: 300  CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347
             GKPG +G +G  GP             GPKG  G  G  GPPG+ GP+G QG  G PGP
Sbjct: 873  AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932

Query: 348  PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393
             GP G PG  G+ G  G +GE G +G+ G PGP GV             GE G PGP GP
Sbjct: 933  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 992

Query: 394  EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439
               PGE+GLPG       +G PGP+G  G +GP G +G  G           G KG  GP
Sbjct: 993  ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049

Query: 440  VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494
             GP GP+G PG     G+ G  G+ G  GP GP GPAG+ G PG KG  G  G  G +GP
Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 495  VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553
            VG+ G  GP G PG  G  G+ G PG+ G+ G KGE G PG  G +GP   G PG  G +
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1167

Query: 554  GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
            G+ G +G QG  G  G EG +G PG  GP G+ G  +PGPPG KG+ G  G  G  G PG
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1225

Query: 614  -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668
                +GP G  GP+GP G+ G + G G  G PG  G PGPPG  G+ G  G+ G KGE  
Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1285

Query: 669  -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720
             PG  GPPG  GP   G  GPKG+ G  G PG PGPPG        G  G KGE G  G 
Sbjct: 1286 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343

Query: 721  PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            PGP G  G     G PG++   G  G  G  G+KG KGE G  G PGK G  GP+G  G
Sbjct: 1344 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1402



 Score =  436 bits (1121), Expect = e-122
 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG   +G +G+ GP G+ G+ G++G  G  G 
Sbjct: 983  ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1040

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362
            PG+KG +G   P GP GP G  G  G  G  GP G  G  G  GPPGP G  GAPG    
Sbjct: 1041 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1094

Query: 363  GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418
              KG +G  GR G  GP+G+     PGP GP G PGE G  GE    G  G KG+KG  G
Sbjct: 1095 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147

Query: 419  PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476
            P GP GLQG +   G  G  G  GP+G  G+   G +G++G +G  GPPGP G  G  G 
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1205

Query: 477  PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526
            PG KGE G +GP GP GP G           G QGP G  GS+G  G+ G PGE G  G 
Sbjct: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1265

Query: 527  KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
             GEAG+ G +G  G      PPG  G PG KG  G  G KGN G  G PG  GP GEPG 
Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325

Query: 580  MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632
             G  G+ G          PGPPGP G+ G PG PG +G PG +  G +G QG +G  G  
Sbjct: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1383

Query: 633  GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683
            G +G  G  G  GP+G  G PGP GLRG    VG+ G  G  G  GPPGP GP G+    
Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1443

Query: 684  ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729
               G++G KG  G  GL GPPG  G        G+QG  G +G  G PGP G +G     
Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766
            GLPG +G  G +G  G  G KG+ G PG PG  G  G
Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  435 bits (1118), Expect = e-121
 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300
            G PG  GPPG  G  G  GE+G  G PG        G  G +G  G+ G KG KGE+GE 
Sbjct: 724  GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 783

Query: 301  GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344
            G PG KGD G  G         P G  GP G +G  GP GDPGP G  G KG+       
Sbjct: 784  GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843

Query: 345  --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400
              PG  GP GS G PG  G  G KG RG  G+PG  G  G  G  G  G RGP G PG +
Sbjct: 844  GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 903

Query: 401  GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443
            G  G +G PGP GE+G +GP GP G  G                   +GE G  G  GP 
Sbjct: 904  GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 963

Query: 444  GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493
            GP G+  +G QG  G  GPIG    PGP GP G QGLPG+ G+ G  G  GP+G      
Sbjct: 964  GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021

Query: 494  PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540
            P G+             G  G KG  G  G PG  G PGE G+AG  G  GLPG  GP+G
Sbjct: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081

Query: 541  PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587
            PPG    KG PG KG +G  G  G QG  GLPGP GP G PG     G  G PG      
Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141

Query: 588  ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633
                   PGPPG +G  G PGI G  GEPG              G +G  GP GP+G  G
Sbjct: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1201

Query: 634  LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673
            L G     G  G  GP G PGPPGP G +G                VG  G KGEPG  G
Sbjct: 1202 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1261

Query: 674  PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726
             PGP G  GVG  GPKG+ G+KG  GPPG   PPG     G  G KG  GP GFPG  G 
Sbjct: 1262 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319

Query: 727  MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779
             G        G+ G KGE G+ G  G  G  GE G PG PGK+G  G  G  G   E+  
Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379

Query: 780  KLITEICGCGPKCKETPL 797
            K   E    GP  K  P+
Sbjct: 1380 K--GEAGAEGPPGKTGPV 1395



 Score =  433 bits (1113), Expect = e-121
 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289
            E+G  G PGPPG  G  G  GE GP+G PG A               G+ G  G  G PG
Sbjct: 617  ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676

Query: 290  YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334
             KG+ G +GE G PG +G+   +G PGP GP GP             G+ G  GPPG PG
Sbjct: 677  PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 736

Query: 335  PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382
             +G  G KG  GPPGP G  G PG           G +G KGE+G++G PG  G +G+  
Sbjct: 737  KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 796

Query: 383  --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405
              GE GQ GPRG +                           GVPG  G PG         
Sbjct: 797  DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 856

Query: 406  --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450
              GFPG  GEKG+             GPTGP+G +G   +G  G  GP G  G  G PG 
Sbjct: 857  FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 914

Query: 451  IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502
             G +G QG QGP+G PGP+GP G        G PG +GE G  G TGP GP G +G QGP
Sbjct: 915  PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974

Query: 503  KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558
             GE G IG  G PG PG  G  G  G AG  GA+G  GP G  G+ GP   +G  G++G 
Sbjct: 975  TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034

Query: 559  KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605
             G QG  GL G EGP+G P            G  GP G+PG   P GPPGP G++G PG 
Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094

Query: 606  PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657
             G +G  G   ++GP G+ GP GP G+PG  GD       G  G  G +G  GPPGP GL
Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154

Query: 658  RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709
            +     G  G PG+ G  G  GPRG  G  G KGD G +G PGPPGP G        G +
Sbjct: 1155 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209

Query: 710  GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762
            G  G+ GP G PGP G  G        G  G  G  G  G VG+KG+ GE G PG PG+ 
Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1269

Query: 763  GLQGPKGDLG 772
            G+ GPKG+ G
Sbjct: 1270 GVGGPKGERG 1279



 Score =  421 bits (1083), Expect = e-117
 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291
            +G PG  GP G  G PG++G  GP G+PG+    G  G  G  G+PG           Y 
Sbjct: 441  EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 500

Query: 292  GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317
            GD                                   G  G  G PG  G KG  G  GP
Sbjct: 501  GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 560

Query: 318  KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370
            +GPRG+QG  GP G PG +      G +G  GEPG  G  G  G PG+ G +G +GERG 
Sbjct: 561  QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620

Query: 371  EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413
            +G PG PG  G+          G PG+ GPR   GP G PG  G PG    +G PGPKG 
Sbjct: 621  QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680

Query: 414  KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473
             G +G  GP G Q     G  G  G  GPQGP+G P  G +G QG  G  G PG  GP G
Sbjct: 681  MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 733

Query: 474  Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531
              G  G  GE G +GP GP+GP+G  G +G KG  G  GL G  G  GEDG  G KG+ G
Sbjct: 734  HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793

Query: 532  LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591
            L G RG       GQ GP+G++G +G KG  G  G PGP G  GE G +G  G+PG   P
Sbjct: 794  LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 846

Query: 592  GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635
            G  GPKG  G PG PG  GE G                 GP+G +G RGP G PG K   
Sbjct: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906

Query: 636  -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681
             GDG PG PG RG  GP GP+G  G              G  G +GE G +G  GP GP 
Sbjct: 907  GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966

Query: 682  G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729
            G VG QGP G+T   G++G PGPPGPPG        G +G KG+ GPQG  G  G  G  
Sbjct: 967  GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1026

Query: 730  GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773
            G PG++G  G +G  G KG +G  G P   GSPG++G  G  G +GL
Sbjct: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073



 Score =  308 bits (788), Expect = 2e-83
 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%)

Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384
           PP     PG P         I   G  GE+GQ+G P          G PGP G    +G 
Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455

Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444
           PG  GP GP G PG+RG PG   PG  G  G  GP G   +      G+ G  GP     
Sbjct: 456 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 512

Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503
                 I  Q    ++GP GP G  G P   G PGS G  G+ G  GP+GP G  VQGP 
Sbjct: 513 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 569

Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563
             PG  G PG+ G PG DG  G  GE G  G RG +G PG       GD+G +G +G QG
Sbjct: 570 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 622

Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622
             G PG +G +GE G +GP G+PG + P G  GP+G  G PG PG  G  G    GPKG 
Sbjct: 623 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 680

Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682
            GP+G  G PG +G+     PGP+GLPGP GP+G    G+ G +G+PG+ G PG  GP G
Sbjct: 681 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 733

Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738
               G +G +G+KG  GPPGP           QGP G+PGP+G  G     GL G KGE 
Sbjct: 734 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           GE      +GD+G KGD+GE+G+ G  G+ G +GPKG  G T
Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 822



 Score =  260 bits (664), Expect = 6e-69
 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296
            EKG+ GD      PGPPG  G  G  G  GP+G PG+   G  G  G  G PG  G+ G 
Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1265

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
             GE G  G KG++G  G  GP G  G  G  GPPGD GPKG  G  G PG PGP G PG 
Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325

Query: 357  PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414
             G  Q G+ G++G++G PG PGP G  GE G PGP G  G PG  G  G +G  G KGE 
Sbjct: 1326 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383

Query: 415  GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451
            G+EGP G               P+GL+G+        + G  G  GP GP GP G+PG+ 
Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1443

Query: 452  ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504
                  G +G  G+ G IGPPG QG  G +GLPG++G  G  G  G  GP G    GP G
Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1501

Query: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544
             PG  G  G  G  G  G AG+KG++GLPG  G  GPPG+
Sbjct: 1502 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541



 Score =  204 bits (520), Expect = 3e-52
 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%)

Query: 243  EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
            EKG+PG+   PGPPG  G  G KGERG KG  G    G AG  G  G PG  G KG  G 
Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1310

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             G PG  G  G PGP G  G  G +G  G PG PGP G  G  G PGPPG  G PGA G 
Sbjct: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1370

Query: 360  ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405
                G++G KGE G EG PG  GP+G  G  G+PGP G  G+PG   E+GLPG       
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1430

Query: 406  -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436
                   G PG KG+ GS+G  G  GL GL      +GEKGD                  
Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490

Query: 437  ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477
                GP+GP GP G+PG              G +G+ G+ GP G PGP G   Q LP
Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547



 Score =  149 bits (375), Expect = 2e-35
 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%)

Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597
           P  PP + + GP        ++ +    G  G +G KGEP ++ P    G  + GPPGP 
Sbjct: 393 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 447

Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656
           G  G              I GP G+QGP GP G PG +G  G PG+PG  GLPGPPG M 
Sbjct: 448 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 493

Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696
           +     G  G+KG                    +RGPPGP G  G  G  G  G +G KG
Sbjct: 494 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553

Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743
             G PGP G   +G++G  GP G PG +G  G     G+PG+ G  G+R         GD
Sbjct: 554 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611

Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G +G++G  G PG PG  G++G  G++G
Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 640



 Score =  105 bits (263), Expect = 2e-22
 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%)

Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647
           P  P  +  GPG+P        SI G  G  G +G  G P     G+  +G PG  GP G
Sbjct: 393 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 451

Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702
           + GPPG  G      TG  G+PG RGPPG  G  G             GLPGPPG     
Sbjct: 452 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 495

Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741
           P  YG  G KG                     +G PGP G  G     G PG  G  GE 
Sbjct: 496 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 555

Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776
           GD G +G +G  G PG    PGK+G  G  G  G+  E
Sbjct: 556 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 593


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  441 bits (1135), Expect = e-123
 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  GP G  G  G +G+RGP+G  G +  KG +G  GP G PG +G  G +G  G 
Sbjct: 742  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 801

Query: 303  PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            PG KG  G PG  G       +G  G QG TGPPG PG  G QG  GE GP G  G PG 
Sbjct: 802  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 861

Query: 357  PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414
            PG  G+QG+ G  G+EG  G PGP G   PG+ GP G  G PGERGLPG  G PG KG +
Sbjct: 862  PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919

Query: 415  GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460
            G  GP GP G  G     G  G IGP G  GP G PG             IG  G  G+Q
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979

Query: 461  GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497
            GP+G PGP GP G                +G  G+KGE G  GP GP GPVG        
Sbjct: 980  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039

Query: 498  ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534
               G +GP+G                PG IGL G PG  GE G  G  G  G PG     
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099

Query: 535  -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586
                   A GP+GPPG  G  GP G++G+ G  G+ G +G PG +GP+GE G  G  G P
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159

Query: 587  GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637
            G   PGPPGPKG       +G PG  GF G+PG     P G  GPRG  GA G +G+   
Sbjct: 1160 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1212

Query: 638  -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680
             G PG PGP G  GPPGP+G RG                 GD GA G PG  GP GP+GP
Sbjct: 1213 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1272

Query: 681  RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720
             G             VG QG  G TGQ G PGP GPPG     G  G KGE+G  G    
Sbjct: 1273 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1332

Query: 721  ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
               PG +G  G  GLPG +G  G++G++G  G  G IG  G PG  G  GPKG  G T
Sbjct: 1333 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390



 Score =  439 bits (1129), Expect = e-123
 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294
            G PG  GPPGT GN G  G +GP G PG             KG  GE+G  G PG+KGD 
Sbjct: 605  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 664

Query: 295  GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345
            G +G+ G+ G+ G +G  GP GPKG       TGP GDPGP G  G KG+         P
Sbjct: 665  GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 718

Query: 346  GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392
            G  GP GS G PG  G  G KG RG  G+ G  G  G  G  GQ GPRG           
Sbjct: 719  GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778

Query: 393  ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447
                P G PGERGLPG    GP G  G +GP GP G  GL    G++G++G  G  GP G
Sbjct: 779  GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 836

Query: 448  IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496
             PG+    G+ GE G  G  G PGP GP G QGLPG+ G+ G  G  GP G      P G
Sbjct: 837  PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 896

Query: 497  I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543
            +             G  G KG  G  G PG  G PGE GAAG  G  G PG  GP+GPPG
Sbjct: 897  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956

Query: 544  ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589
                KG PG KG  G  G  G QG  GLPGP GP G   E G  G  G PG         
Sbjct: 957  AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1016

Query: 590  ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634
                PGPPGP G  G PG  G  GEPG   RGP            +G  GP GP+G  GL
Sbjct: 1017 EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1074

Query: 635  KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674
             G              G PG PGPRG  GP G       P G+  +G  G KGEPG  G 
Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134

Query: 675  PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733
            PG  G  GV G +G +G+ G+ G PG PGPPG   +G  G+ GP+G PGP G  G   PG
Sbjct: 1135 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1190

Query: 734  QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772
              GE G RG  G KGD+GE GE   PGSPG  G  GP G LG
Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232



 Score =  431 bits (1109), Expect = e-120
 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  G  G  G+PG+KG+RG  G PG   +KG  G+ G  G+PG  G+ GERG+ G+
Sbjct: 451  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356
             G +G  G  GP G  GP+G  GI GPPG        GPKG  G +GEPGPPG  G+PG 
Sbjct: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 570

Query: 357  PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407
             G+    G  G  GE+G +G+PG PG P   G PG PG  GP G  G +G  G     G+
Sbjct: 571  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630

Query: 408  PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463
            PGP+G KG +G  G +G +G        G KGDIG  G +G +G+P  GS+GE G +GP 
Sbjct: 631  PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 688

Query: 464  GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522
            G  GP G  G   PG  GE G++G  G P  P   G QGPK   GS+G PG PG  GE G
Sbjct: 689  GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 740

Query: 523  AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573
            A G  G++G  G RGP GP  +GQ GP+G  GK G+KG           G+RGLPGP+GP
Sbjct: 741  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798

Query: 574  KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602
             G PG  GP G PG                   T  PGPP            GP G+RG 
Sbjct: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858

Query: 603  PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659
            PG PG  GE GL    G +G +G  GP GAPG  G  G  G PG RGLPG  G  GL+G 
Sbjct: 859  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 660  ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712
                   G  G+ GE G  G  GP GP G  G QGP G  G+KG+PG  GP   G  G  
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 976

Query: 713  GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G QGP G PGP G    G+ G+ G+ GE GD G+KG KG  GE G PG  G  GP G  G
Sbjct: 977  GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1034



 Score =  426 bits (1095), Expect = e-119
 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG    G  G+ GP G+ G+ G++G  G  G 
Sbjct: 855  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 912

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347
            PG+KG++G  GP GP G  G +G        GPPG PGP         KG  G KG  GP
Sbjct: 913  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972

Query: 348  ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385
                        PGP G PG  G           GQ+G KG +G+ G PG PGPI  G  
Sbjct: 973  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1030

Query: 386  GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443
            GQPG  G +G PG RG  G  G  G +G +G  GP GP GLQGL    GEKG+ G VGP 
Sbjct: 1031 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090

Query: 444  GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501
            GP G PG  G  G  G  GP GPPG  G    G PG KGE G+ G  G +G  G+ G +G
Sbjct: 1091 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560
             +GE G  G PG+PG PG  G  G  G  G PG  G  G PG  G+ GP+G +G KG +G
Sbjct: 1149 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1208

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
              G+ G PG  GP GE G  GP G  G    PG  G +G +G  G PG  G PG +  GP
Sbjct: 1209 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1266

Query: 620  KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671
             G  GP G  G  GL+G        G PG  G  G PGP GP GL G+ GD GAKGE G 
Sbjct: 1267 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1326

Query: 672  RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730
             G  G  GP   G QG KGD   +GLPGP G PG  G  GI G  GP G  GP G  G  
Sbjct: 1327 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381

Query: 731  LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763
              G KG  G  G  G KG+KG  G PG PG  G
Sbjct: 1382 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279
           GDPG+ GPPG  G PG  G  GP G           G   KG                  
Sbjct: 337 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 396

Query: 280 -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336
              RGP G  GY G  G  G+ G PG+KG+ G  GP GP+GP   QG+TGPPG  G +  
Sbjct: 397 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 453

Query: 337 -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394
            G  G +G PG PG  G  G  G+ G  G KG RG  G  G PGP     PG+ G RG +
Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 508

Query: 395 GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450
           G  G RGLPGE  P    GPKG  G  GP G +G+ G   +G KG +GP G  GP G  G
Sbjct: 509 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 566

Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507
             G+QG  G QG IGP G +GP G+ GLPG  G  G  G  G  GP G  G QGP G  G
Sbjct: 567 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626

Query: 508 SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
            +G PG  GV G DG        G+KGE G PG +G  G  G     G PG +G++G +G
Sbjct: 627 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 686

Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614
            KG  G  G PGP G  GE G +G  G+PG   PG  GPKG  G PG PG  GE G    
Sbjct: 687 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 744

Query: 615 ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659
                        GP+G +GPRG  G  G K    GDG  G PG RGLPGP GP G  G 
Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804

Query: 660 ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703
                        G  G +GE G +G  GP GP G VG QG  G+T   G++G PGPPGP
Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864

Query: 704 PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755
           PG        G +G KG+ GP G PG  G  G  G PG++G  G  G  G KG++G  G 
Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924

Query: 756 P---GSPGKQGLQGPKGDLG 772
           P   GSPG++G  G  G +G
Sbjct: 925 PGPAGSPGERGAAGSGGPIG 944



 Score =  377 bits (967), Expect = e-104
 Identities = 260/654 (39%), Positives = 308/654 (47%), Gaps = 132/654 (20%)

Query: 233 KKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-----QKGEAGERGPG-- 285
           + CE+K  ECE G    P     H     + +R P+  P        Q+ ++ +  PG  
Sbjct: 219 ESCEQKELECEGGQRERPQNQQPH-----RAQRSPQQQPSRLHRPQNQEPQSQDPTPGEE 273

Query: 286 --------------GIPGYKGDKGERGECG--KPG--IKGDKGSPGPYGPKGPRGIQGIT 327
                            G +G KGE+GE    +PG  ++G  G  GP G  GP GIQG  
Sbjct: 274 EEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNP 333

Query: 328 GPPGDPGPKGFQGNKGEP------------------------------------------ 345
           GP GDPG +G  G  G P                                          
Sbjct: 334 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 393

Query: 346 -------GPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGP 393
                  GPPGP G  G PG     G  G+KGE G  G  G  GP G+ G PG+ G RG 
Sbjct: 394 QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 453

Query: 394 EGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQ 443
            G  G RG+PG          +G PG  GEKG  G TG QGL G    GE G+ G  G  
Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEI 511

Query: 444 GPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502
           GP G+P  G  G +G+ GP GPPG  GP G +G+ G +G  G +GP G  GP      G 
Sbjct: 512 GPRGLP--GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-----PGQ 564

Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGN 561
           +G PG+ GLPG  G  G  G  G +G+ GLPG  G +GPPG  G+ GP G +G +G  G 
Sbjct: 565 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 624

Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGL 614
           QG  G PGP G KG  GI G  G  G           G  G KGDRG  G+PG +GE G 
Sbjct: 625 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG- 683

Query: 615 SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVR 672
              GPKG  GP G  G PGL G+ G  GVPG  G PG  GP G  G  G  GA GE G R
Sbjct: 684 -PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742

Query: 673 GPPGPSGPRGV-------GTQGPKGDTGQKGL------PGPPGPPGYGSQGIKGEQGPQG 719
           G  G SGPRG        G +GP+G TG+ G        GP GPP  G +G+ G QGP G
Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--GERGLPGPQGPNG 800

Query: 720 FPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           FPGPKG  G  G  G  G  G+RG+VG +G  G  G PG  G QG  G  G +G
Sbjct: 801 FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 854



 Score =  306 bits (785), Expect = 5e-83
 Identities = 202/469 (43%), Positives = 237/469 (50%), Gaps = 56/469 (11%)

Query: 360 GQQGIKGERGQ----------EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP 408
           G +G+KGE+G+          EG PG  GP G +G PG  G  GP G PGERG PG    
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 348

Query: 409 GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP--- 465
           G  G  G+ GP G   +         GD GPV          I  Q    ++GP GP   
Sbjct: 349 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 408

Query: 466 PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGE 520
            G  GP GQ G PG KGE G +GP GPRGP G+    G  G +G  G+ G  G PG PG 
Sbjct: 409 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 468

Query: 521 DGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
            G  G  G  GLPG +G  G  G +G PGP G++G++G  G  G RGLPG  GP+G  G 
Sbjct: 469 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528

Query: 580 MGPFGMPGT----SIPGPPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGP 628
            GP G+PG      + GP GPKG    +G PG PG +G PG   + GP+G  GP   +GP
Sbjct: 529 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588

Query: 629 VGAPGLKG----DGYPGVPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGP 677
            G PGL G    DG PG PG  G PG      P GP G  G  G  G KG  G+RG  G 
Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648

Query: 678 SGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH--- 729
            G +G  G  G KGD G KG  G  G PG     G +G KG  GP G PGP G MG    
Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708

Query: 730 ----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
               GLPG  G  G +G +G  G  G  GE G+ G  G  GP+G+ G T
Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757



 Score =  296 bits (757), Expect = 1e-79
 Identities = 197/508 (38%), Positives = 254/508 (50%), Gaps = 85/508 (16%)

Query: 338 FQGNKGE----PGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG------PIGVGEPGQ 387
           F+G+  E    PG    Y S     +  +G + ER Q  +P          P  +  P  
Sbjct: 201 FEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQN 260

Query: 388 PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI--GPVGPQGP 445
             P+  +  PGE     E    P  E+ + GP G +G +G     E G +  GP GP+GP
Sbjct: 261 QEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 320

Query: 446 MGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPT-----------GPRG 493
            G+  IG  G QG  GP+G PG +GP G+ GLPGS G  G  G +           G +G
Sbjct: 321 AGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 378

Query: 494 PVGIGVQGP------------KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541
           PV    +              +G PG +G  G+PG  G+ G+ G KGE+G  G +GP GP
Sbjct: 379 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 438

Query: 542 PGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS----------IP 591
             +G  GP G  G++G  G  G RG+PG  G KG+ G  G  G+PG            +P
Sbjct: 439 --QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 496

Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGP 651
           GPPG  G+RG  G  G +G PG S  GP+G+ GP+GP         G PG PG RG+ GP
Sbjct: 497 GPPGEDGERGDDGEIGPRGLPGES--GPRGLLGPKGP--------PGIPGPPGVRGMDGP 546

Query: 652 PGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY 706
            GP G  G     G  G +G PG +G PGP G  G  G +GP+G  G  G+PG  GPPG+
Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606

Query: 707 ----------GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGE------RGDVGK 746
                     G+QG  G QGP G+PGP+G  G     GL G KGE GE      +GD+G 
Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666

Query: 747 KGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           KGD+GE+G PGS G+ G +GPKG  G T
Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPT 694



 Score =  288 bits (737), Expect = 2e-77
 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292
            EKG+ GD      PGPPG  G  G  G  GP+G PG        GE GE G  G PG +G
Sbjct: 1080 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1139

Query: 293  DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
            + G +G  G+ G KG+ G PG  GP GP+G  G  GP G+PGP GF G+ G PG  GP G
Sbjct: 1140 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199

Query: 353  SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410
              GA     +G +GE G+ G+PG+PGP G  G PG  G RGP G PG  G   G+G  G 
Sbjct: 1200 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1254

Query: 411  KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469
             G  G+ G TGP         G  G  G  GP G  G+PG +G QG  G  G  GPPGP 
Sbjct: 1255 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1306

Query: 470  GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
            GP   GLPG +G+ G  G  G  G +G IG  G +GE G  GLPG  G PG+      KG
Sbjct: 1307 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1358

Query: 529  EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587
            E G+PGA GP GP G  G PGP G +G KG+          GP GPKGE G+ GP     
Sbjct: 1359 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1404

Query: 588  TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643
               PG PGP G+   P          L I+ PK     V G R       +   G PG P
Sbjct: 1405 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1451

Query: 644  G 644
            G
Sbjct: 1452 G 1452



 Score =  102 bits (254), Expect = 2e-21
 Identities = 81/272 (29%), Positives = 111/272 (40%), Gaps = 76/272 (27%)

Query: 542 PGKGQPGPKGDEGKKGSKGNQ---GQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598
           P + Q  P+    +     NQ    Q   PG E    E  ++ P      +  GP G KG
Sbjct: 241 PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLE---EAAHGPRGLKG 297

Query: 599 DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLR 658
           ++G P +     EPG+ + GP G +GP               G+ GP G+ G PGP+   
Sbjct: 298 EKGEPAVL----EPGMLVEGPPGPEGPA--------------GLIGPPGIQGNPGPV--- 336

Query: 659 GVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG-----PPGYGSQG--- 710
                   G+PG RGPPG +G             G  G PGPPG     P  +GS G   
Sbjct: 337 --------GDPGERGPPGRAGL-----------PGSDGAPGPPGTSLMLPFRFGSGGGDK 377

Query: 711 ---------------------IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKG 748
                                ++G  GP G+ G  G +G  G PG KGE G+ G  G +G
Sbjct: 378 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 437

Query: 749 DKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780
            +G  G PG  G++G  G  G  G+  +  +K
Sbjct: 438 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 469


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  441 bits (1135), Expect = e-123
 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  GP G  G  G +G+RGP+G  G +  KG +G  GP G PG +G  G +G  G 
Sbjct: 721  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 780

Query: 303  PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            PG KG  G PG  G       +G  G QG TGPPG PG  G QG  GE GP G  G PG 
Sbjct: 781  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840

Query: 357  PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414
            PG  G+QG+ G  G+EG  G PGP G   PG+ GP G  G PGERGLPG  G PG KG +
Sbjct: 841  PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898

Query: 415  GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460
            G  GP GP G  G     G  G IGP G  GP G PG             IG  G  G+Q
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958

Query: 461  GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497
            GP+G PGP GP G                +G  G+KGE G  GP GP GPVG        
Sbjct: 959  GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018

Query: 498  ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534
               G +GP+G                PG IGL G PG  GE G  G  G  G PG     
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078

Query: 535  -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586
                   A GP+GPPG  G  GP G++G+ G  G+ G +G PG +GP+GE G  G  G P
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138

Query: 587  GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637
            G   PGPPGPKG       +G PG  GF G+PG     P G  GPRG  GA G +G+   
Sbjct: 1139 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1191

Query: 638  -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680
             G PG PGP G  GPPGP+G RG                 GD GA G PG  GP GP+GP
Sbjct: 1192 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1251

Query: 681  RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720
             G             VG QG  G TGQ G PGP GPPG     G  G KGE+G  G    
Sbjct: 1252 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1311

Query: 721  ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
               PG +G  G  GLPG +G  G++G++G  G  G IG  G PG  G  GPKG  G T
Sbjct: 1312 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1369



 Score =  439 bits (1129), Expect = e-123
 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294
            G PG  GPPGT GN G  G +GP G PG             KG  GE+G  G PG+KGD 
Sbjct: 584  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 643

Query: 295  GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345
            G +G+ G+ G+ G +G  GP GPKG       TGP GDPGP G  G KG+         P
Sbjct: 644  GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 697

Query: 346  GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392
            G  GP GS G PG  G  G KG RG  G+ G  G  G  G  GQ GPRG           
Sbjct: 698  GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 757

Query: 393  ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447
                P G PGERGLPG    GP G  G +GP GP G  GL    G++G++G  G  GP G
Sbjct: 758  GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 815

Query: 448  IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496
             PG+    G+ GE G  G  G PGP GP G QGLPG+ G+ G  G  GP G      P G
Sbjct: 816  PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 875

Query: 497  I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543
            +             G  G KG  G  G PG  G PGE GAAG  G  G PG  GP+GPPG
Sbjct: 876  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 935

Query: 544  ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589
                KG PG KG  G  G  G QG  GLPGP GP G   E G  G  G PG         
Sbjct: 936  AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 995

Query: 590  ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634
                PGPPGP G  G PG  G  GEPG   RGP            +G  GP GP+G  GL
Sbjct: 996  EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1053

Query: 635  KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674
             G              G PG PGPRG  GP G       P G+  +G  G KGEPG  G 
Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1113

Query: 675  PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733
            PG  G  GV G +G +G+ G+ G PG PGPPG   +G  G+ GP+G PGP G  G   PG
Sbjct: 1114 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1169

Query: 734  QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772
              GE G RG  G KGD+GE GE   PGSPG  G  GP G LG
Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211



 Score =  431 bits (1109), Expect = e-120
 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  G  G  G+PG+KG+RG  G PG   +KG  G+ G  G+PG  G+ GERG+ G+
Sbjct: 430  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356
             G +G  G  GP G  GP+G  GI GPPG        GPKG  G +GEPGPPG  G+PG 
Sbjct: 490  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549

Query: 357  PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407
             G+    G  G  GE+G +G+PG PG P   G PG PG  GP G  G +G  G     G+
Sbjct: 550  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609

Query: 408  PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463
            PGP+G KG +G  G +G +G        G KGDIG  G +G +G+P  GS+GE G +GP 
Sbjct: 610  PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 667

Query: 464  GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522
            G  GP G  G   PG  GE G++G  G P  P   G QGPK   GS+G PG PG  GE G
Sbjct: 668  GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 719

Query: 523  AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573
            A G  G++G  G RGP GP  +GQ GP+G  GK G+KG           G+RGLPGP+GP
Sbjct: 720  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 777

Query: 574  KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602
             G PG  GP G PG                   T  PGPP            GP G+RG 
Sbjct: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837

Query: 603  PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659
            PG PG  GE GL    G +G +G  GP GAPG  G  G  G PG RGLPG  G  GL+G 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 660  ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712
                   G  G+ GE G  G  GP GP G  G QGP G  G+KG+PG  GP   G  G  
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 955

Query: 713  GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G QGP G PGP G    G+ G+ G+ GE GD G+KG KG  GE G PG  G  GP G  G
Sbjct: 956  GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013



 Score =  426 bits (1095), Expect = e-119
 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG    G  G+ GP G+ G+ G++G  G  G 
Sbjct: 834  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 891

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347
            PG+KG++G  GP GP G  G +G        GPPG PGP         KG  G KG  GP
Sbjct: 892  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951

Query: 348  ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385
                        PGP G PG  G           GQ+G KG +G+ G PG PGPI  G  
Sbjct: 952  TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1009

Query: 386  GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443
            GQPG  G +G PG RG  G  G  G +G +G  GP GP GLQGL    GEKG+ G VGP 
Sbjct: 1010 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1069

Query: 444  GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501
            GP G PG  G  G  G  GP GPPG  G    G PG KGE G+ G  G +G  G+ G +G
Sbjct: 1070 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560
             +GE G  G PG+PG PG  G  G  G  G PG  G  G PG  G+ GP+G +G KG +G
Sbjct: 1128 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1187

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
              G+ G PG  GP GE G  GP G  G    PG  G +G +G  G PG  G PG +  GP
Sbjct: 1188 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1245

Query: 620  KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671
             G  GP G  G  GL+G        G PG  G  G PGP GP GL G+ GD GAKGE G 
Sbjct: 1246 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1305

Query: 672  RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730
             G  G  GP   G QG KGD   +GLPGP G PG  G  GI G  GP G  GP G  G  
Sbjct: 1306 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360

Query: 731  LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763
              G KG  G  G  G KG+KG  G PG PG  G
Sbjct: 1361 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279
           GDPG+ GPPG  G PG  G  GP G           G   KG                  
Sbjct: 316 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 375

Query: 280 -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336
              RGP G  GY G  G  G+ G PG+KG+ G  GP GP+GP   QG+TGPPG  G +  
Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 432

Query: 337 -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394
            G  G +G PG PG  G  G  G+ G  G KG RG  G  G PGP     PG+ G RG +
Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 487

Query: 395 GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450
           G  G RGLPGE  P    GPKG  G  GP G +G+ G   +G KG +GP G  GP G  G
Sbjct: 488 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 545

Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507
             G+QG  G QG IGP G +GP G+ GLPG  G  G  G  G  GP G  G QGP G  G
Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605

Query: 508 SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
            +G PG  GV G DG        G+KGE G PG +G  G  G     G PG +G++G +G
Sbjct: 606 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665

Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614
            KG  G  G PGP G  GE G +G  G+PG   PG  GPKG  G PG PG  GE G    
Sbjct: 666 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 723

Query: 615 ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659
                        GP+G +GPRG  G  G K    GDG  G PG RGLPGP GP G  G 
Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783

Query: 660 ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703
                        G  G +GE G +G  GP GP G VG QG  G+T   G++G PGPPGP
Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843

Query: 704 PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755
           PG        G +G KG+ GP G PG  G  G  G PG++G  G  G  G KG++G  G 
Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903

Query: 756 P---GSPGKQGLQGPKGDLG 772
           P   GSPG++G  G  G +G
Sbjct: 904 PGPAGSPGERGAAGSGGPIG 923



 Score =  385 bits (990), Expect = e-107
 Identities = 258/633 (40%), Positives = 304/633 (48%), Gaps = 111/633 (17%)

Query: 233 KKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG 292
           + CE+K  ECE G    P     H     + +R P+  P    + +  E       G +G
Sbjct: 219 ESCEQKELECEGGQRERPQNQQPH-----RAQRSPQQQPSRLHRPQNQEPQSQAAHGPRG 273

Query: 293 DKGERGECG--KPG--IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEP--- 345
            KGE+GE    +PG  ++G  G  GP G  GP GIQG  GP GDPG +G  G  G P   
Sbjct: 274 LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 333

Query: 346 ----------------------------------------------GPPGPYGSPGAPG- 358
                                                         GPPGP G  G PG 
Sbjct: 334 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 393

Query: 359 ---IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG---------- 404
               G  G+KGE G  G  G  GP G+ G PG+ G RG  G  G RG+PG          
Sbjct: 394 LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 453

Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIG 464
           +G PG  GEKG  G TG QGL G    GE G+ G  G  GP G+P  G  G +G+ GP G
Sbjct: 454 DGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLP--GESGPRGLLGPKG 509

Query: 465 PPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523
           PPG  GP G +G+ G +G  G +GP G  GP      G +G PG+ GLPG  G  G  G 
Sbjct: 510 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE 564

Query: 524 AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582
            G +G+ GLPG  G +GPPG  G+ GP G +G +G  G QG  G PGP G KG  GI G 
Sbjct: 565 KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 624

Query: 583 FGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
            G  G           G  G KGDRG  G+PG +GE G    GPKG  GP G  G PGL 
Sbjct: 625 KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG--PEGPKGRTGPTGDPGPPGLM 682

Query: 636 GD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-------GTQ 686
           G+ G  GVPG  G PG  GP G  G  G  GA GE G RG  G SGPRG        G +
Sbjct: 683 GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742

Query: 687 GPKGDTGQKGL------PGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG 739
           GP+G TG+ G        GP GPP  G +G+ G QGP GFPGPKG  G  G  G  G  G
Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPP--GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 800

Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           +RG+VG +G  G  G PG  G QG  G  G +G
Sbjct: 801 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 833



 Score =  306 bits (785), Expect = 5e-83
 Identities = 202/469 (43%), Positives = 237/469 (50%), Gaps = 56/469 (11%)

Query: 360 GQQGIKGERGQ----------EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP 408
           G +G+KGE+G+          EG PG  GP G +G PG  G  GP G PGERG PG    
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 327

Query: 409 GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP--- 465
           G  G  G+ GP G   +         GD GPV          I  Q    ++GP GP   
Sbjct: 328 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 387

Query: 466 PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGE 520
            G  GP GQ G PG KGE G +GP GPRGP G+    G  G +G  G+ G  G PG PG 
Sbjct: 388 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 447

Query: 521 DGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579
            G  G  G  GLPG +G  G  G +G PGP G++G++G  G  G RGLPG  GP+G  G 
Sbjct: 448 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507

Query: 580 MGPFGMPGT----SIPGPPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGP 628
            GP G+PG      + GP GPKG    +G PG PG +G PG   + GP+G  GP   +GP
Sbjct: 508 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567

Query: 629 VGAPGLKG----DGYPGVPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGP 677
            G PGL G    DG PG PG  G PG      P GP G  G  G  G KG  G+RG  G 
Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627

Query: 678 SGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH--- 729
            G +G  G  G KGD G KG  G  G PG     G +G KG  GP G PGP G MG    
Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687

Query: 730 ----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
               GLPG  G  G +G +G  G  G  GE G+ G  G  GP+G+ G T
Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736



 Score =  290 bits (741), Expect = 7e-78
 Identities = 191/483 (39%), Positives = 241/483 (49%), Gaps = 101/483 (20%)

Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420
           Q+ ++ E GQ  RP    P           R P+  P     P         E  S+   
Sbjct: 223 QKELECEGGQRERPQNQQP-------HRAQRSPQQQPSRLHRP------QNQEPQSQAAH 269

Query: 421 GPQGLQGLSIKGEKGDI----------GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQG 470
           GP+GL     KGEKG+           GP GP+GP G+  IG  G QG  GP+G PG +G
Sbjct: 270 GPRGL-----KGEKGEPAVLEPGMLVEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERG 322

Query: 471 PAGQ-GLPGSKGEVGQMGPT-----------GPRGPVGIGVQGP------------KGEP 506
           P G+ GLPGS G  G  G +           G +GPV    +              +G P
Sbjct: 323 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382

Query: 507 GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566
           G +G  G+PG  G+ G+ G KGE+G  G +GP GP  +G  GP G  G++G  G  G RG
Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP--QGLTGPPGKAGRRGRAGADGARG 440

Query: 567 LPGPEGPKGEPGIMGPFGMPGTS----------IPGPPGPKGDRGGPGIPGFKGEPGLSI 616
           +PG  G KG+ G  G  G+PG            +PGPPG  G+RG  G  G +G PG S 
Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES- 499

Query: 617 RGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672
            GP+G+ GP+GP         G PG PG RG+ GP GP G  G     G  G +G PG +
Sbjct: 500 -GPRGLLGPKGP--------PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 550

Query: 673 GPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFP 721
           G PGP G  G  G +GP+G  G  G+PG  GPPG+          G+QG  G QGP G+P
Sbjct: 551 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610

Query: 722 GPKGTMG----HGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771
           GP+G  G     GL G KGE GE      +GD+G KGD+GE+G PGS G+ G +GPKG  
Sbjct: 611 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 670

Query: 772 GLT 774
           G T
Sbjct: 671 GPT 673



 Score =  288 bits (737), Expect = 2e-77
 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292
            EKG+ GD      PGPPG  G  G  G  GP+G PG        GE GE G  G PG +G
Sbjct: 1059 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1118

Query: 293  DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
            + G +G  G+ G KG+ G PG  GP GP+G  G  GP G+PGP GF G+ G PG  GP G
Sbjct: 1119 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178

Query: 353  SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410
              GA     +G +GE G+ G+PG+PGP G  G PG  G RGP G PG  G   G+G  G 
Sbjct: 1179 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1233

Query: 411  KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469
             G  G+ G TGP         G  G  G  GP G  G+PG +G QG  G  G  GPPGP 
Sbjct: 1234 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1285

Query: 470  GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
            GP   GLPG +G+ G  G  G  G +G IG  G +GE G  GLPG  G PG+      KG
Sbjct: 1286 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1337

Query: 529  EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587
            E G+PGA GP GP G  G PGP G +G KG+          GP GPKGE G+ GP     
Sbjct: 1338 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1383

Query: 588  TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643
               PG PGP G+   P          L I+ PK     V G R       +   G PG P
Sbjct: 1384 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1430

Query: 644  G 644
            G
Sbjct: 1431 G 1431



 Score =  101 bits (252), Expect = 3e-21
 Identities = 68/195 (34%), Positives = 90/195 (46%), Gaps = 48/195 (24%)

Query: 618 GPKGVQGPRGP--VGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675
           GP+G++G +G   V  PG+  +G PG  GP GL GPPG  G     + G  G+PG RGPP
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG-----NPGPVGDPGERGPP 324

Query: 676 GPSGPRGVGTQGPKGDTGQKGLPGPPG-----PPGYGSQG-------------------- 710
           G +G             G  G PGPPG     P  +GS G                    
Sbjct: 325 GRAGL-----------PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 373

Query: 711 ----IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765
               ++G  GP G+ G  G +G  G PG KGE G+ G  G +G +G  G PG  G++G  
Sbjct: 374 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433

Query: 766 GPKGDLGLTKEEIIK 780
           G  G  G+  +  +K
Sbjct: 434 GADGARGMPGDPGVK 448


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  441 bits (1135), Expect = e-123
 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  GP G  G  G +G+RGP+G  G +  KG +G  GP G PG +G  G +G  G 
Sbjct: 828  RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 887

Query: 303  PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            PG KG  G PG  G       +G  G QG TGPPG PG  G QG  GE GP G  G PG 
Sbjct: 888  PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 947

Query: 357  PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414
            PG  G+QG+ G  G+EG  G PGP G   PG+ GP G  G PGERGLPG  G PG KG +
Sbjct: 948  PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005

Query: 415  GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460
            G  GP GP G  G     G  G IGP G  GP G PG             IG  G  G+Q
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065

Query: 461  GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497
            GP+G PGP GP G                +G  G+KGE G  GP GP GPVG        
Sbjct: 1066 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125

Query: 498  ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534
               G +GP+G                PG IGL G PG  GE G  G  G  G PG     
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185

Query: 535  -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586
                   A GP+GPPG  G  GP G++G+ G  G+ G +G PG +GP+GE G  G  G P
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245

Query: 587  GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637
            G   PGPPGPKG       +G PG  GF G+PG     P G  GPRG  GA G +G+   
Sbjct: 1246 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1298

Query: 638  -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680
             G PG PGP G  GPPGP+G RG                 GD GA G PG  GP GP+GP
Sbjct: 1299 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1358

Query: 681  RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720
             G             VG QG  G TGQ G PGP GPPG     G  G KGE+G  G    
Sbjct: 1359 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1418

Query: 721  ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
               PG +G  G  GLPG +G  G++G++G  G  G IG  G PG  G  GPKG  G T
Sbjct: 1419 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1476



 Score =  439 bits (1129), Expect = e-123
 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294
            G PG  GPPGT GN G  G +GP G PG             KG  GE+G  G PG+KGD 
Sbjct: 691  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 750

Query: 295  GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345
            G +G+ G+ G+ G +G  GP GPKG       TGP GDPGP G  G KG+         P
Sbjct: 751  GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 804

Query: 346  GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392
            G  GP GS G PG  G  G KG RG  G+ G  G  G  G  GQ GPRG           
Sbjct: 805  GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 864

Query: 393  ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447
                P G PGERGLPG    GP G  G +GP GP G  GL    G++G++G  G  GP G
Sbjct: 865  GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 922

Query: 448  IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496
             PG+    G+ GE G  G  G PGP GP G QGLPG+ G+ G  G  GP G      P G
Sbjct: 923  PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 982

Query: 497  I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543
            +             G  G KG  G  G PG  G PGE GAAG  G  G PG  GP+GPPG
Sbjct: 983  LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 1042

Query: 544  ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589
                KG PG KG  G  G  G QG  GLPGP GP G   E G  G  G PG         
Sbjct: 1043 AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1102

Query: 590  ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634
                PGPPGP G  G PG  G  GEPG   RGP            +G  GP GP+G  GL
Sbjct: 1103 EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1160

Query: 635  KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674
             G              G PG PGPRG  GP G       P G+  +G  G KGEPG  G 
Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1220

Query: 675  PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733
            PG  G  GV G +G +G+ G+ G PG PGPPG   +G  G+ GP+G PGP G  G   PG
Sbjct: 1221 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1276

Query: 734  QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772
              GE G RG  G KGD+GE GE   PGSPG  G  GP G LG
Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1318



 Score =  431 bits (1109), Expect = e-120
 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            +G  G  G  G  G+PG+KG+RG  G PG   +KG  G+ G  G+PG  G+ GERG+ G+
Sbjct: 537  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356
             G +G  G  GP G  GP+G  GI GPPG        GPKG  G +GEPGPPG  G+PG 
Sbjct: 597  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 656

Query: 357  PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407
             G+    G  G  GE+G +G+PG PG P   G PG PG  GP G  G +G  G     G+
Sbjct: 657  QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 716

Query: 408  PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463
            PGP+G KG +G  G +G +G        G KGDIG  G +G +G+P  GS+GE G +GP 
Sbjct: 717  PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 774

Query: 464  GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522
            G  GP G  G   PG  GE G++G  G P  P   G QGPK   GS+G PG PG  GE G
Sbjct: 775  GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 826

Query: 523  AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573
            A G  G++G  G RGP GP  +GQ GP+G  GK G+KG           G+RGLPGP+GP
Sbjct: 827  ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884

Query: 574  KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602
             G PG  GP G PG                   T  PGPP            GP G+RG 
Sbjct: 885  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944

Query: 603  PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659
            PG PG  GE GL    G +G +G  GP GAPG  G  G  G PG RGLPG  G  GL+G 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 660  ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712
                   G  G+ GE G  G  GP GP G  G QGP G  G+KG+PG  GP   G  G  
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 1062

Query: 713  GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G QGP G PGP G    G+ G+ G+ GE GD G+KG KG  GE G PG  G  GP G  G
Sbjct: 1063 GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1120



 Score =  426 bits (1095), Expect = e-119
 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            E+G PG PGPPG  G PG  G+ G KG+PG    G  G+ GP G+ G+ G++G  G  G 
Sbjct: 941  ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 998

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347
            PG+KG++G  GP GP G  G +G        GPPG PGP         KG  G KG  GP
Sbjct: 999  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058

Query: 348  ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385
                        PGP G PG  G           GQ+G KG +G+ G PG PGPI  G  
Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1116

Query: 386  GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443
            GQPG  G +G PG RG  G  G  G +G +G  GP GP GLQGL    GEKG+ G VGP 
Sbjct: 1117 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1176

Query: 444  GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501
            GP G PG  G  G  G  GP GPPG  G    G PG KGE G+ G  G +G  G+ G +G
Sbjct: 1177 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560
             +GE G  G PG+PG PG  G  G  G  G PG  G  G PG  G+ GP+G +G KG +G
Sbjct: 1235 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1294

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
              G+ G PG  GP GE G  GP G  G    PG  G +G +G  G PG  G PG +  GP
Sbjct: 1295 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1352

Query: 620  KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671
             G  GP G  G  GL+G        G PG  G  G PGP GP GL G+ GD GAKGE G 
Sbjct: 1353 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1412

Query: 672  RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730
             G  G  GP   G QG KGD   +GLPGP G PG  G  GI G  GP G  GP G  G  
Sbjct: 1413 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467

Query: 731  LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763
              G KG  G  G  G KG+KG  G PG PG  G
Sbjct: 1468 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498



 Score =  420 bits (1080), Expect = e-117
 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279
            GDPG+ GPPG  G PG  G  GP G           G   KG                  
Sbjct: 423  GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 482

Query: 280  -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336
               RGP G  GY G  G  G+ G PG+KG+ G  GP GP+GP   QG+TGPPG  G +  
Sbjct: 483  LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 539

Query: 337  -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394
             G  G +G PG PG  G  G  G+ G  G KG RG  G  G PGP     PG+ G RG +
Sbjct: 540  AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 594

Query: 395  GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450
            G  G RGLPGE  P    GPKG  G  GP G +G+ G   +G KG +GP G  GP G  G
Sbjct: 595  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 652

Query: 451  I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507
              G+QG  G QG IGP G +GP G+ GLPG  G  G  G  G  GP G  G QGP G  G
Sbjct: 653  TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712

Query: 508  SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557
             +G PG  GV G DG        G+KGE G PG +G  G  G     G PG +G++G +G
Sbjct: 713  PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 772

Query: 558  SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614
             KG  G  G PGP G  GE G +G  G+PG   PG  GPKG  G PG PG  GE G    
Sbjct: 773  PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 830

Query: 615  ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659
                         GP+G +GPRG  G  G K    GDG  G PG RGLPGP GP G  G 
Sbjct: 831  SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890

Query: 660  ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703
                         G  G +GE G +G  GP GP G VG QG  G+T   G++G PGPPGP
Sbjct: 891  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950

Query: 704  PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755
            PG        G +G KG+ GP G PG  G  G  G PG++G  G  G  G KG++G  G 
Sbjct: 951  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010

Query: 756  P---GSPGKQGLQGPKGDLG 772
            P   GSPG++G  G  G +G
Sbjct: 1011 PGPAGSPGERGAAGSGGPIG 1030



 Score =  373 bits (958), Expect = e-103
 Identities = 252/600 (42%), Positives = 292/600 (48%), Gaps = 109/600 (18%)

Query: 264 ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG--IKGDKGSPGPYGPKGPR 321
           E GP  +   A  G A   GP G+   KG+KGE     +PG  ++G  G  GP G  GP 
Sbjct: 359 ELGPALSAETAHSGAAAH-GPRGL---KGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPP 413

Query: 322 GIQGITGPPGDPGPKGFQGNKGEP------------------------------------ 345
           GIQG  GP GDPG +G  G  G P                                    
Sbjct: 414 GIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQ 473

Query: 346 -------------GPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGV-GEPGQ 387
                        GPPGP G  G PG     G  G+KGE G  G  G  GP G+ G PG+
Sbjct: 474 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 533

Query: 388 PGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI 437
            G RG  G  G RG+PG          +G PG  GEKG  G TG QGL G    GE G+ 
Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGER 591

Query: 438 GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG 496
           G  G  GP G+P  G  G +G+ GP GPPG  GP G +G+ G +G  G +GP G  GP  
Sbjct: 592 GDDGEIGPRGLP--GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-- 647

Query: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGK 555
               G +G PG+ GLPG  G  G  G  G +G+ GLPG  G +GPPG  G+ GP G +G 
Sbjct: 648 ---PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704

Query: 556 KGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGF 608
           +G  G QG  G PGP G KG  GI G  G  G           G  G KGDRG  G+PG 
Sbjct: 705 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764

Query: 609 KGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAK 666
           +GE G    GPKG  GP G  G PGL G+ G  GVPG  G PG  GP G  G  G  GA 
Sbjct: 765 RGEDG--PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 822

Query: 667 GEPGVRGPPGPSGPRGV-------GTQGPKGDTGQKGL------PGPPGPPGYGSQGIKG 713
           GE G RG  G SGPRG        G +GP+G TG+ G        GP GPP  G +G+ G
Sbjct: 823 GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--GERGLPG 880

Query: 714 EQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            QGP GFPGPKG  G  G  G  G  G+RG+VG +G  G  G PG  G QG  G  G +G
Sbjct: 881 PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 940



 Score =  310 bits (793), Expect = 6e-84
 Identities = 214/512 (41%), Positives = 252/512 (49%), Gaps = 63/512 (12%)

Query: 324 QGITGPPGDPGPK--GFQGNKGEPGPPGPYGSP-----GAPGIGQQGIKGERGQ------ 370
           +G T PP  P     G+  +  E    GP  S      GA   G +G+KGE+G+      
Sbjct: 334 EGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEP 393

Query: 371 ----EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGL 425
               EG PG  GP G +G PG  G  GP G PGERG PG    G  G  G+ GP G   +
Sbjct: 394 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA--GLPGSDGAPGPPGTSLM 451

Query: 426 QGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP---PGPQGPAGQ-GLPGSKG 481
                    GD GPV          I  Q    ++GP GP    G  GP GQ G PG KG
Sbjct: 452 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 511

Query: 482 EVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARG 537
           E G +GP GPRGP G+    G  G +G  G+ G  G PG PG  G  G  G  GLPG +G
Sbjct: 512 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 571

Query: 538 PEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT----SIPG 592
             G  G +G PGP G++G++G  G  G RGLPG  GP+G  G  GP G+PG      + G
Sbjct: 572 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 631

Query: 593 PPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGPVGAPGLKG----DGYPG 641
           P GPKG    +G PG PG +G PG   + GP+G  GP   +GP G PGL G    DG PG
Sbjct: 632 PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 691

Query: 642 VPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693
            PG  G PG      P GP G  G  G  G KG  G+RG  G  G +G  G  G KGD G
Sbjct: 692 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 751

Query: 694 QKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERG 742
            KG  G  G PG     G +G KG  GP G PGP G MG        GLPG  G  G +G
Sbjct: 752 VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 811

Query: 743 DVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            +G  G  G  GE G+ G  G  GP+G+ G T
Sbjct: 812 SLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843



 Score =  288 bits (737), Expect = 2e-77
 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%)

Query: 243  EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292
            EKG+ GD      PGPPG  G  G  G  GP+G PG        GE GE G  G PG +G
Sbjct: 1166 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1225

Query: 293  DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
            + G +G  G+ G KG+ G PG  GP GP+G  G  GP G+PGP GF G+ G PG  GP G
Sbjct: 1226 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1285

Query: 353  SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410
              GA     +G +GE G+ G+PG+PGP G  G PG  G RGP G PG  G   G+G  G 
Sbjct: 1286 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1340

Query: 411  KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469
             G  G+ G TGP         G  G  G  GP G  G+PG +G QG  G  G  GPPGP 
Sbjct: 1341 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1392

Query: 470  GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528
            GP   GLPG +G+ G  G  G  G +G IG  G +GE G  GLPG  G PG+      KG
Sbjct: 1393 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1444

Query: 529  EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587
            E G+PGA GP GP G  G PGP G +G KG+          GP GPKGE G+ GP     
Sbjct: 1445 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1490

Query: 588  TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643
               PG PGP G+   P          L I+ PK     V G R       +   G PG P
Sbjct: 1491 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1537

Query: 644  G 644
            G
Sbjct: 1538 G 1538



 Score =  288 bits (736), Expect = 3e-77
 Identities = 189/467 (40%), Positives = 235/467 (50%), Gaps = 94/467 (20%)

Query: 383 GEPGQPGPRGPE----GVPGERGLPGEGFPGPKGEKGSEGPT--GPQGLQGLSIKGEKGD 436
           GE G   P GP     G   +     E  P    E    G    GP+GL     KGEKG+
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGL-----KGEKGE 387

Query: 437 I----------GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQ 485
                      GP GP+GP G+  IG  G QG  GP+G PG +GP G+ GLPGS G  G 
Sbjct: 388 PAVLEPGMLVEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGP 445

Query: 486 MGPT-----------GPRGPVGIGVQGP------------KGEPGSIGLPGQPGVPGEDG 522
            G +           G +GPV    +              +G PG +G  G+PG  G+ G
Sbjct: 446 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG 505

Query: 523 AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582
           + G KGE+G  G +GP GP  +G  GP G  G++G  G  G RG+PG  G KG+ G  G 
Sbjct: 506 SPGLKGESGDLGPQGPRGP--QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 563

Query: 583 FGMPGTS----------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632
            G+PG            +PGPPG  G+RG  G  G +G PG S  GP+G+ GP+GP    
Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES--GPRGLLGPKGP---- 617

Query: 633 GLKGDGYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQG 687
                G PG PG RG+ GP GP G  G     G  G +G PG +G PGP G  G  G +G
Sbjct: 618 ----PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673

Query: 688 PKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPGPKGTMG----HGLPG 733
           P+G  G  G+PG  GPPG+          G+QG  G QGP G+PGP+G  G     GL G
Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 733

Query: 734 QKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
            KGE GE      +GD+G KGD+GE+G PGS G+ G +GPKG  G T
Sbjct: 734 HKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780



 Score =  238 bits (606), Expect = 3e-62
 Identities = 173/423 (40%), Positives = 202/423 (47%), Gaps = 72/423 (17%)

Query: 412 GEKGSEGPTGPQGLQ-------------GLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQG 458
           GE G++ P GP                 G ++  E    G     GP G+ G   +GE  
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAA-HGPRGLKG--EKGEPA 389

Query: 459 IQGP----IGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPG 513
           +  P     GPPGP+GPAG  G PG +G  G +G  G RGP      G  G PGS G PG
Sbjct: 390 VLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-----PGRAGLPGSDGAPG 444

Query: 514 QPG----VPGEDGAAG-----------KKGEAGLPGAR----GPEGPPG-KGQPGPKGDE 553
            PG    +P   G+ G            + +A L  AR    GP GP G  G+PGP G  
Sbjct: 445 PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 504

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIP 606
           G  G KG  G  G  GP GP+G  G  G  G  G +       +PG PG KGDRG  G+P
Sbjct: 505 GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 564

Query: 607 GFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAK 666
           G  GE G   RG  G QG  GP G  G +GD   G  GPRGLPG  GP GL      G K
Sbjct: 565 GLPGEKGH--RGDTGAQGLPGPPGEDGERGDD--GEIGPRGLPGESGPRGL-----LGPK 615

Query: 667 GEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725
           G PG+ GPPG  G  G   QGPKG  G +G PGPPG  G  G+QG+ G QG  G  G KG
Sbjct: 616 GPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673

Query: 726 TMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITE 784
             G  GLPG  G  G  G  GK+G       PG+ G QG  GP+G LG      +K +  
Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGP------PGTKGNQGPSGPQGPLGYPGPRGVKGVDG 727

Query: 785 ICG 787
           I G
Sbjct: 728 IRG 730


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  435 bits (1119), Expect = e-121
 Identities = 291/683 (42%), Positives = 342/683 (50%), Gaps = 163/683 (23%)

Query: 244  KGDPGDPG-----------PPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG 292
            +GD GDPG           PPG  G+PG+ G++G  G+P     G  G+RG  G+PG KG
Sbjct: 724  RGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG 783

Query: 293  DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP------KGFQGNKGEPG 346
                RG+ G PG +G  G PG  G KGP+G +G  G PG PGP      +G  G  G+PG
Sbjct: 784  P---RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPG 840

Query: 347  PPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV----------GEPG 386
             PG  GSPGAPG           G  G+KG  G  GRPGA GP G+          G PG
Sbjct: 841  LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPG 900

Query: 387  QPGPRGPEGVPG------ERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGP 439
             PGP+GP G+PG      ERG PG EG PG KGE G +G +G  G +GL  +G KG IGP
Sbjct: 901  PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGL--RGAKGAIGP 958

Query: 440  VGPQGPM------------------GIPGI-GSQGEQGIQGPIGPPGPQGPAG--QGLPG 478
             G +G M                  G PG  G +G  G+QG  G PG  GP G  +G PG
Sbjct: 959  PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG 1018

Query: 479  SKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531
             KG+ G  GP GP G  G+       G+ G +GEPGS   PG PG  G DGA G KG  G
Sbjct: 1019 EKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS---PGPPGFSGIDGARGPKGNKG 1075

Query: 532  LP----GARGPEGPPGK----GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583
             P    G  GP+G PG     G  G  G++G  G +G +G  G PGP G  G PG  G  
Sbjct: 1076 DPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDH 1135

Query: 584  GMPGT-------SIPGPPGPKGDRGGPGIPGFKG---EPGLS----IRGPKGVQG----- 624
            GMPG          PGP G +GD G PG PG KG    PGL+    ++G KG +G     
Sbjct: 1136 GMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLH 1195

Query: 625  ---PRGPVGAPGLKGD----GYPGV--PGPRGLPGPPGPMGLRGV-GDTGAKGE------ 668
               P GPVG PGLKG+    G PG+  PGPRG  GPPGP G  G  G  GA G       
Sbjct: 1196 DVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIP 1255

Query: 669  ----PGVRGPPGPSGPRGV--------------GTQGPKGDTGQKGLPGPPGPPGY---- 706
                PG +GPPGP GPRG               G  G  G  G  G PGPPGPPGY    
Sbjct: 1256 DPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFP 1315

Query: 707  GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGE----------- 755
            G  G  G++GP GFPGP+G   HG PG  GE G  G  G+KG  G  G            
Sbjct: 1316 GCDGKDGQKGPVGFPGPQGP--HGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373

Query: 756  -----PGSPGKQGLQGPKGDLGL 773
                 PG PG  G++GP+G +GL
Sbjct: 1374 DCPRIPGLPGAPGMRGPEGAMGL 1396



 Score =  424 bits (1089), Expect = e-118
 Identities = 281/664 (42%), Positives = 326/664 (49%), Gaps = 146/664 (21%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQ----------KGEAGERGPGGIPGYKGDK 294
            G  GDPGPPG  G PG+ G+ G  G PGN            KG  GERGP G PG+ G  
Sbjct: 524  GTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQP 583

Query: 295  GERGECGKPGIKGDKGSPGPY--GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
            G  G  G  G KGD G PG +     G +G  G  GPPG  GP G  G  G PGPPG  G
Sbjct: 584  GSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPGERG 642

Query: 353  SPGAPGI----GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGF 407
             PG PG     G  G+KG++G         P   G PG  GP GP+G PG +G PG  G 
Sbjct: 643  HPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGS 702

Query: 408  PGPKGEKGSEGPT---GPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQ 460
             G KG  G+ G     GP G +G        GEKG   PVGP GP G PG+   G++GI 
Sbjct: 703  DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS-SPVGPPGPPGSPGVN--GQKGIP 759

Query: 461  GP-----IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGL 511
            G      +GPPG +G +G  +PG KG  G  G  G  GP GI    G++GPKG  G  G 
Sbjct: 760  GDPAFGHLGPPGKRGLSG--VPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGF 817

Query: 512  PGQPGVPG---EDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGL 567
            PG PG PG   E GA G  G+ GLPG  G  G PG KGQPG  G  G  G KG  G  G 
Sbjct: 818  PGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGR 877

Query: 568  PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGF---------------KGEP 612
            PG  GP G PGI GPFG  G  +PGPPGPKG RG PG PGF               KGEP
Sbjct: 878  PGAHGPPGLPGIPGPFGDDG--LPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEP 935

Query: 613  G----LSIRGPKGVQGPRGPVGAPGLKG-------------------DGYPGV------- 642
            G      + G +G++G +G +G PG +G                   DG+PG        
Sbjct: 936  GEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTP 995

Query: 643  ---------------------------PGPRGLPGPPGPMGLRGV----GDTGAKGEPGV 671
                                       PGP G PGPPG  GLRG     G  G +GEPG 
Sbjct: 996  GMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS 1055

Query: 672  RGPPGPSGPRGV-GTQGPKGDT-------GQKGLPGPPGPPGY----GSQGIKGEQGPQG 719
             GPPG SG  G  G +G KGD        G KG PG PG PG+    G QG+ G QGP+G
Sbjct: 1056 PGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRG 1115

Query: 720  FPG---PKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769
             PG   P G+ G       HG+PG +G+ GE GD G +G +   G+PG PG  G++GP G
Sbjct: 1116 SPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQ---GDPGIPGPPGIKGPSG 1172

Query: 770  DLGL 773
              GL
Sbjct: 1173 SPGL 1176



 Score =  417 bits (1072), Expect = e-116
 Identities = 269/598 (44%), Positives = 305/598 (51%), Gaps = 81/598 (13%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            KG PG PG PG HG PG+ G  GP G+ G    G  G +GP G+PG+ G  GERG+ G  
Sbjct: 869  KGLPGLPGRPGAHGPPGLPGIPGPFGDDG--LPGPPGPKGPRGLPGFPGFPGERGKPGAE 926

Query: 304  GIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
            G  G KG PG  G       +G RG +G  GPPGD G       KG PG PGP G  G P
Sbjct: 927  GCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFP 986

Query: 358  GI-GQQGIKGERGQEGRPGAPGPIGV-----GEPGQPGPRGPEGVPGERGLPG----EGF 407
            G  G +G  G +G+ G PG  GP G      GE GQPGP GP G PG  GL G     G 
Sbjct: 987  GERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGL 1046

Query: 408  PGPKGEKGSEGPTGPQGLQGL-SIKGEKGD----IGPVGPQGPMGIPGI-------GSQG 455
            PG +GE GS GP G  G+ G    KG KGD     GP GP+G  G PG        G QG
Sbjct: 1047 PGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQG 1106

Query: 456  EQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE 505
              GIQGP G PG  GP G           G+PG +G+ G+MG  GPRG     +QG  G 
Sbjct: 1107 LPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG-----LQGDPGI 1161

Query: 506  PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPE--GPPGK-GQPGPKGDEGKKGSKG-- 560
            PG  G+ G  G PG +G  G KG+ G  GA G    GPPG  G PG KG+ G  GS G  
Sbjct: 1162 PGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS 1221

Query: 561  ---NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP--------GPPGPKGDRGGPGIPGF- 608
                +G++G PGP G  G PG  G  G     IP        GPPGP G RG PG PG  
Sbjct: 1222 PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLP 1281

Query: 609  ------KGEPG-LSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV 660
                  +GEPG   + GP G  GP GP G  G  G DG  G  GP G PGP GP G  G 
Sbjct: 1282 GSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGP 1341

Query: 661  -GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ----KGLPGPPGPPG-YGSQGIKGE 714
             G+ G  G PG +GP G  GPRG    GP  D        GLPG PG  G  G+ G+ G 
Sbjct: 1342 PGEKGLPGPPGRKGPTGLPGPRG--EPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGM 1399

Query: 715  QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            +GP G PG KG  G  L G++G  G  G  G  G KG+ GE G PG  G  GP GD G
Sbjct: 1400 RGPSG-PGCKGEPG--LDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPG 1454



 Score =  409 bits (1052), Expect = e-114
 Identities = 271/648 (41%), Positives = 317/648 (48%), Gaps = 139/648 (21%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKG---NPGNAQKGEAGERGPGGIPGYKGDKGERG-- 298
           KG PGDPG PG +G  G  G  GP G    PG A  G  G  GP G PG  G  GE G  
Sbjct: 366 KGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIP 425

Query: 299 --------ECGKPGIKGDKGSPG------------PYGPKGPRGIQGITGPPGDPGPKGF 338
                   + GKPG  G  G+PG              G  GP+GI+G  GPPG  GPKG 
Sbjct: 426 GRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGE 485

Query: 339 QGNKG----EPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGP 393
           +GN+G    EPGP GP G PG PG  +QG KG+ G       PG +G  G+PG PG  GP
Sbjct: 486 KGNEGLCACEPGPMGPPGPPGLPG--RQGSKGDLG------LPGWLGTKGDPGPPGAEGP 537

Query: 394 EGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453
            G+PG+ G  G   PG KG KG         +    +KG KG+ GP GP G  G PG  S
Sbjct: 538 PGLPGKHGASGP--PGNKGAKGD--------MVVSRVKGHKGERGPDGPPGFPGQPG--S 585

Query: 454 QGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGP---TGPRGPVGIGVQGPKGEPGSIG 510
            G  G  G  G PGP G      PG KG  G +GP    GP GP G+G  GP GE G  G
Sbjct: 586 HGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPG 645

Query: 511 LPGQPGVPGEDGAAGKKGEA-----GLPGARGP---EGPPG-KGQPGPKGDEGKKGSKGN 561
           +PG PGV G DG  G+KG+        PG  GP   +GPPG KG PGP+G  G  GS G+
Sbjct: 646 VPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGH 705

Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPG------TSIPGPPGPKGDRGGPGIPGFKGEPGLS 615
           +G+ G PG     G PG  G  G PG      +S  GPPGP G  G  G  G  G+P   
Sbjct: 706 KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765

Query: 616 IRGPKG---------VQGPRGPVGAPGLKGD-------------------GYPGVPGP-- 645
             GP G         ++GPRG  G PG +G                    G+PGVPGP  
Sbjct: 766 HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG 825

Query: 646 ----RGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-------GTQGPKG 690
               RG PG PG  GL G     G  G KG+PG  GPPGP+G +G+       G  GP G
Sbjct: 826 HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885

Query: 691 ------DTGQKGLPGPPGP------PGY-GSQGIKGEQGPQGFPGPKGTMGH----GLPG 733
                   G  GLPGPPGP      PG+ G  G +G+ G +G PG KG  G     GLPG
Sbjct: 886 LPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPG 945

Query: 734 QKGEHGERGDVGKKGDKGEI---------GEPGSPGKQGLQGPKGDLG 772
            +G  G +G +G  GD+GE+         GEPG PG  G  G +GD G
Sbjct: 946 DRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993



 Score =  404 bits (1038), Expect = e-112
 Identities = 259/615 (42%), Positives = 310/615 (50%), Gaps = 106/615 (17%)

Query: 242  CEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPG---YKGDKGERG 298
            C    PG  GPPG  G PG KG  GP+G PG +  G  G +G  G PG     G  G RG
Sbjct: 668  CNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLS--GSDGHKGRPGTPGTAEIPGPPGFRG 725

Query: 299  ECGKPGIKGDKGSP--GPYGPKGPRGIQGITGPPGDP-----GPKGFQGNKGEPGPPGPY 351
            + G PG  G+KGS   GP GP G  G+ G  G PGDP     GP G +G  G PG  GP 
Sbjct: 726  DMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPR 785

Query: 352  GSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401
            G PG PG          +G +G KG  G  G PG PGP     PG    RG  G+PG+ G
Sbjct: 786  GDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGP-----PGHSCERGAPGIPGQPG 840

Query: 402  LPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGE 456
            LPG     G PG KG+ G  GP GP G++GL      G  G  G  GP G+PGI G  G+
Sbjct: 841  LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLP-----GLPGRPGAHGPPGLPGIPGPFGD 895

Query: 457  QGIQGPIGPPGPQG-------------PAGQGLPGSKGEVGQMGPTGPRGPVGI----GV 499
             G+ GP GP GP+G             P  +G PG+KGE G+ G +G  G  G+    G 
Sbjct: 896  DGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGA 955

Query: 500  QGPKGEPGSI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553
             GP G+ G +      G PG+PG PG+DG  G++G+ G PG +G  G PG+   GP G  
Sbjct: 956  IGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY--GPPGFH 1013

Query: 554  GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
              +G  G +GQ G PGP GP G  G+ G  G PG      PG +G+ G PG PGF G  G
Sbjct: 1014 --RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGL-----PGDQGEPGSPGPPGFSGIDG 1066

Query: 614  LSIRGPKGVQG-------PRGPVGAPGLKG----------DGYPGVPGPRGLPGPPGPMG 656
               RGPKG +G       P GP G PG  G           G PG+ GPRG PG PGP G
Sbjct: 1067 A--RGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPG 1124

Query: 657  LRGV-GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGE 714
              G  G  G  G PG+RG PG      +G  GP+G  G  G+PGPPG  G  GS G+ G 
Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGE-----MGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGL 1179

Query: 715  QGPQGFPGPKGTMGH---------GLPGQKGEHGERGDVG--KKGDKGEIGEPGSPGKQG 763
             G +G  G KG  G          G+PG KGE G+ G  G    G +G+ G PG PG  G
Sbjct: 1180 HGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSG 1239

Query: 764  LQGPKGDLGLTKEEI 778
              GP G  G   ++I
Sbjct: 1240 PPGPAGATGRAPKDI 1254



 Score =  401 bits (1031), Expect = e-111
 Identities = 268/650 (41%), Positives = 313/650 (48%), Gaps = 136/650 (20%)

Query: 243  EKGDPGDPGPPGT-----------------------HGNPGIKGERGPKGNPG----NAQ 275
            E+G PG PG PG                        HG PG  G  GPKG PG       
Sbjct: 640  ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699

Query: 276  KGEAGERGPGGIPG---YKGDKGERGECGKPGIKGDKGSP--GPYGPKGPRGIQGITGPP 330
             G  G +G  G PG     G  G RG+ G PG  G+KGS   GP GP G  G+ G  G P
Sbjct: 700  SGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIP 759

Query: 331  GDP-----GPKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPG 375
            GDP     GP G +G  G PG  GP G PG PG          +G +G KG  G  G PG
Sbjct: 760  GDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPG 819

Query: 376  APGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIK 431
             PGP     PG    RG  G+PG+ GLPG     G PG KG+ G  GP GP G++GL   
Sbjct: 820  VPGP-----PGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL--- 871

Query: 432  GEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQG-------------PAGQGLP 477
               G  G  G  GP G+PGI G  G+ G+ GP GP GP+G             P  +G P
Sbjct: 872  --PGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929

Query: 478  GSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSI------GLPGQPGVPGEDGAAGKK 527
            G+KGE G+ G +G  G  G+    G  GP G+ G +      G PG+PG PG+DG  G++
Sbjct: 930  GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989

Query: 528  GEAGLPGARGPEGPPG--------------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGP 573
            G+ G PG +G  G PG              KGQPGP G  G  GS G +G  G PG  G 
Sbjct: 990  GDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD 1049

Query: 574  KGEPGIMGPFGMPG--------------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
            +GEPG  GP G  G               S  GPPGPKG+ G PG PG  G  G   +G 
Sbjct: 1050 QGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASG--EQGL 1107

Query: 620  KGVQGPRGPVGAPGLKG-DGYPGVPGPRGLP---------GPPGPMGLRGVGDTGAKGEP 669
             G+QGPRG  G PG  G  G PG PG  G+P         G PGP GL+  GD G  G P
Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQ--GDPGIPGPP 1165

Query: 670  GVRGPPGPSGPRGV-GTQGPKGDTGQKGL--PGPPGPPGYGSQGIKGEQGPQGFPG--PK 724
            G++GP G  G  G+ G +G KG  G  GL   GPPGP   G  G+KGE+G  G PG  P 
Sbjct: 1166 GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP--VGIPGLKGERGDPGSPGISPP 1223

Query: 725  GTMG-HGLPGQKGEHGERGDVGKKG-DKGEIGEPGSPGKQGLQGPKGDLG 772
            G  G  G PG  G  G  G  G  G    +I +PG PG QG  GP G  G
Sbjct: 1224 GPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRG 1273



 Score =  392 bits (1008), Expect = e-109
 Identities = 281/711 (39%), Positives = 329/711 (46%), Gaps = 187/711 (26%)

Query: 239 ICEC--EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296
           +C C  EKG  G PGPPG  G  G  G  GP G  G  +KG  G+RGP G  G KGDKG 
Sbjct: 54  VCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSG--EKGMRGDRGPPGAAGDKGDKGP 111

Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            G  G PG+ G  G PGP GP+G  G+ G  G  GDP   GF G +G  GP GP G PG 
Sbjct: 112 TGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDP---GFPGGRGALGPGGPLGHPGE 168

Query: 357 PG--------IGQ-QGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGER 400
            G        +G  +GI+G+RG  G PG PG  G        G PG+PG  GP G PG  
Sbjct: 169 KGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRP 228

Query: 401 GLPG------------------EGFPGP------------KGEKGSE---------GPTG 421
           GL G                  +G PGP            KGEKG +         GP G
Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288

Query: 422 PQGLQGLSIKGEKGDIGPVGPQ------GPMGIPG----IGSQGEQGIQGPIGP------ 465
            +G  G+  KGEKG  G  GP+      G  G PG    +G  G+ G+ G IGP      
Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGN 348

Query: 466 ---PGPQG------------PAGQGLPGSKGEVGQMGPTGPRGPVG---------IGVQG 501
              PGP G            P   G PG  GE G +GP GP G +G         IG  G
Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPG 408

Query: 502 PKGEPGSIGLPGQPGVPGE----DGAAGKKGEAGLPGARGPEGPPGK-------GQPGPK 550
           P+G PG  GLPG+ G+PG      G  GK G  GLPGA G +G PG        G PGP+
Sbjct: 409 PQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQ 468

Query: 551 GDEGK------KGSKGNQGQRGL----PGPEGPKGEPGI------MGPFGMPG----TSI 590
           G +GK      +G KG +G  GL    PGP GP G PG+       G  G+PG       
Sbjct: 469 GIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGD 528

Query: 591 PGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPGL------ 634
           PGPPG +G  G PG  G  G PG            ++G KG +GP GP G PG       
Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588

Query: 635 ------KGD---------------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRG 673
                 KGD               G+PG  GP G  GP GP GL   G  G +G PGV G
Sbjct: 589 DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPG 648

Query: 674 PPGPSGPRGVGTQGPKGDTGQKGL--PGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGH- 729
            PG  GP G+  +G KGDT    +  PG  GPPG+ G  G KG  GPQG PG  G+ GH 
Sbjct: 649 HPGVRGPDGL--KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHK 706

Query: 730 ---------GLPGQKGEHGERGDVGKKGDKGE--IGEPGSPGKQGLQGPKG 769
                     +PG  G  G+ GD G  G+KG   +G PG PG  G+ G KG
Sbjct: 707 GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKG 757



 Score =  368 bits (945), Expect = e-101
 Identities = 239/511 (46%), Positives = 281/511 (54%), Gaps = 86/511 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECG 301
            +KG PG+PGPPG  G PG   ERG KG PG   ++GE G  GP G   ++G+ GE+G+ G
Sbjct: 970  QKGTPGEPGPPGDDGFPG---ERGDKGTPGMQGRRGEPGRYGPPGF--HRGEPGEKGQPG 1024

Query: 302  KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---------QGNKGEP----GPP 348
             PG  G  GS G  G  G  G+ G  G PG PGP GF         +GNKG+P    GPP
Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084

Query: 349  GPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401
            GP G PG+PG        G+QG+ G +G  G PG PGP   G  G PG  G  G+PG RG
Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP--PGSSGPPGCPGDHGMPGLRG 1142

Query: 402  LPGE-GFPGPKGEKGSEGPTGPQGLQGLS----------IKGEKGDIGP-----VGPQGP 445
             PGE G PGP+G +G  G  GP G++G S          +KG+KG  G      VGP GP
Sbjct: 1143 QPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP 1202

Query: 446  MGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI------ 497
            +GIPG+ G +G+ G  G I PPGP+G  G  G PGS G  G  G TG R P  I      
Sbjct: 1203 VGIPGLKGERGDPGSPG-ISPPGPRGKKGPPGPPGSSGPPGPAGATG-RAPKDIPDPGPP 1260

Query: 498  GVQGPKGEPGSIGLPGQPGVPGE-DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK 556
            G QGP G  G  G PG PG+PG  D   G+ G+ GLPG  GP GPPG   PG KG  G  
Sbjct: 1261 GDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP--PGYKGFPGCD 1318

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGP---PGPKGDRGG-PGI 605
            G  G +G  G PGP+GP G PG  G  G+PG       T +PGP   PGP  D    P I
Sbjct: 1319 GKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRI 1378

Query: 606  PGFKGEPGLSIRGPKGVQG---PRGPVGAPGLKGDGYPGVPGPRGL---PGPPGPMGLRG 659
            PG  G PG+  RGP+G  G    RGP G PG KG+  PG+ G RG+   PG PGP G +G
Sbjct: 1379 PGLPGAPGM--RGPEGAMGLPGMRGPSG-PGCKGE--PGLDGRRGVDGVPGSPGPPGRKG 1433

Query: 660  VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKG 690
              DTG  G PG  GPPGP     +G  GPKG
Sbjct: 1434 --DTGEDGYPGGPGPPGP-----IGDPGPKG 1457



 Score =  319 bits (817), Expect = 1e-86
 Identities = 218/539 (40%), Positives = 258/539 (47%), Gaps = 97/539 (17%)

Query: 306 KGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIK 365
           KG +G PGP GP+GP G  G  GP G  G KG +G++G PG  G  G  G  G+   G  
Sbjct: 61  KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGV--PGFP 118

Query: 366 GERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG----FPGPKGEKGS---- 416
           G  G  G PG PGP G  G  G  G RG  G PG RG  G G     PG KGEKG+    
Sbjct: 119 GLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFI 178

Query: 417 -------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGP- 468
                  +G  G  GL GL      G  G  GP GP G PG     E G+ GP G PG  
Sbjct: 179 LGAVKGIQGDRGDPGLPGLP-----GSWGAGGPAGPTGYPG-----EPGLVGPPGQPGRP 228

Query: 469 --QGPAGQGLPGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPG 516
             +G  G G+ G  G+ G++G  G  GP  +          G +G KG PG +GLPG PG
Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288

Query: 517 VPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
             GE G  G KGE G+PG  GP G PG  G PG  G +G+ G  G+ G  GL GP+G  G
Sbjct: 289 RKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPG 347

Query: 576 EPGIMGPFGM---PGTSIPGPPGPKG---------DRGGPGIPGFKGEPGLSIRGPKGVQ 623
             G  GP G+   P   + GPPG  G         D G PG PG  G PG +  G  G  
Sbjct: 348 NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPP 407

Query: 624 GPRGPVGAPGLKGD-----------GYPGVPGPRGLPGPPGPMGLRGVG----DTGAKGE 668
           GP+G  G PGL G+           G PG PG  GLPG PG  GL G        G  G 
Sbjct: 408 GPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGP 467

Query: 669 PGVRGPPGPSGPRGVGTQGPKGDTGQKGL----PGPPGPPGYGSQGIKGEQGPQGFPGPK 724
            G++G  GP G RG     PKG+ G +GL    PGP GPPG           P G PG +
Sbjct: 468 QGIKGKVGPPGGRG-----PKGEKGNEGLCACEPGPMGPPG-----------PPGLPGRQ 511

Query: 725 GTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLI 782
           G+ G  GLPG  G  G+ G  G +G       PG PGK G  GP G+ G   + ++  +
Sbjct: 512 GSKGDLGLPGWLGTKGDPGPPGAEGP------PGLPGKHGASGPPGNKGAKGDMVVSRV 564



 Score =  303 bits (775), Expect = 8e-82
 Identities = 194/456 (42%), Positives = 226/456 (49%), Gaps = 82/456 (17%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK--GEAGERGPGGIPGYKGDKGERGECGK 302
            GD G+PG PG  G  GI G RGPKGN G+     G  G +G  G PG  G  G  GE G 
Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGL 1107

Query: 303  PGIKGDKGSPGPYGPKGP---------RGIQGITGPPG---DPGPKGFQGNKGEPGPPG- 349
            PGI+G +GSPG  GP G           G+ G+ G PG   DPGP+G QG+ G PGPPG 
Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGI 1167

Query: 350  --PYGSPGAPG------------------------IGQQGIKGERGQEGRPGAPGPIGVG 383
              P GSPG  G                        +G  G+KGERG  G PG   P   G
Sbjct: 1168 KGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRG 1227

Query: 384  EPGQPGPRGPEGVPGERGLPGEG-----FPGPKGEKGSEGPTGPQGLQGLS--------I 430
            + G PGP G  G PG  G  G        PGP G++G  GP GP+G  G          +
Sbjct: 1228 KKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLL 1287

Query: 431  KGEKGDI---GPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEV 483
            +GE GD    GP GP GP G PG     G  G+ G +GP+G PGPQGP   G PG  GE 
Sbjct: 1288 RGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP--HGFPGPPGEK 1345

Query: 484  GQMGPTGPRGPVGIGVQGPKGEPGSIG----LPGQPGVPGEDGAAGKKGEAGLPGARGPE 539
            G  GP G +GP G+   GP+GEPG        P  PG+PG  G  G +G  GLPG RGP 
Sbjct: 1346 GLPGPPGRKGPTGL--PGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPS 1403

Query: 540  GPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGD 599
            GP  KG+P         G  G +G  G+PG  GP G  G  G  G PG   PGPPGP GD
Sbjct: 1404 GPGCKGEP---------GLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGG--PGPPGPIGD 1452

Query: 600  RGGPGI-PGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
             G  G  PG+ G   L +   +  Q P  P+G P L
Sbjct: 1453 PGPKGFGPGYLG-GFLLVLHSQTDQEPTCPLGMPRL 1487



 Score =  234 bits (597), Expect = 3e-61
 Identities = 158/377 (41%), Positives = 187/377 (49%), Gaps = 45/377 (11%)

Query: 437 IGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPV 495
           IGP G +       +  +G +G  GP GP GP GP G   P G  GE G  G  GP G  
Sbjct: 44  IGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAA 103

Query: 496 G-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPK 550
           G  G +GP G PG  GL G PG PG  G  GK G +G  G+RG  G PG     G  GP 
Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163

Query: 551 GDEGKKGSKGNQ-----GQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRG 601
           G  G+KG KGN        +G+ G  G  G PG+ G +G  G    T  PG PG  G  G
Sbjct: 164 GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPG 223

Query: 602 GPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPG------------LKGD-GYPGVPGPRGL 648
            PG PG KG PG+ ++G  G  G  G  G+PG             KG+ G  G+PG  GL
Sbjct: 224 QPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGL 283

Query: 649 PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGPPGYG 707
           PGPPG  G  G+   GAKGE G+ G PGP G P   G+ G  G  G+ GL G PG   +G
Sbjct: 284 PGPPGRKGESGI---GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL--FG 338

Query: 708 SQGIKGEQGPQGFPGPKGTM---------GHGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758
             G KG+ G +G PGP G +           G PG  G +GE GDVG  G  G +G PG 
Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398

Query: 759 --PGKQGLQGPKGDLGL 773
              G  G  GP+G  GL
Sbjct: 399 ACAGMIGPPGPQGFPGL 415



 Score =  233 bits (593), Expect = 1e-60
 Identities = 148/347 (42%), Positives = 171/347 (49%), Gaps = 55/347 (15%)

Query: 240  CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERG 298
            C  + G PG  G PG  G+PG +G +G  G PG    KG +G  G  G+ G KG KG +G
Sbjct: 1131 CPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKG 1190

Query: 299  ECGK-----------PGIKGDKGSPGPYG--PKGPRGIQGITGPPGDPGPKGFQGNKG-- 343
              G            PG+KG++G PG  G  P GPRG +G  GPPG  GP G  G  G  
Sbjct: 1191 ASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRA 1250

Query: 344  -----EPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV--------GEPGQPGP 390
                 +PGPPG  G PG          G RG  G PG PG + +        G PG PGP
Sbjct: 1251 PKDIPDPGPPGDQGPPGP--------DGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGP 1302

Query: 391  RGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449
             GP G PG +G PG +G  G KG  G  GP GP G  G    GEKG  GP G +GP G+P
Sbjct: 1303 PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG--PPGEKGLPGPPGRKGPTGLP 1360

Query: 450  GIGSQGEQGIQGPIGPPG-----PQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504
                    G +G  GPP      P+ P   G PG +G  G MG  G RGP G G +G  G
Sbjct: 1361 --------GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPG 1412

Query: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKG 551
              G  G+ G PG PG  G  G  GE G PG  GP GP   G PGPKG
Sbjct: 1413 LDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGP--IGDPGPKG 1457


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  434 bits (1115), Expect = e-121
 Identities = 270/609 (44%), Positives = 314/609 (51%), Gaps = 91/609 (14%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGY---KGDKGERGEC 300
           G+PG+ G  G  G PG++GE G +G  G   +KGEAG  G  G PG    KGD+GE+GE 
Sbjct: 250 GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGEL 309

Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGIT-------------------GPPGDPGPKGFQGN 341
           G PG+KGD+G  G  GP GP G+ G T                   G PG PG  G QG 
Sbjct: 310 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 369

Query: 342 KGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401
            GE GP GP G PGA   GQ+G  G  G  G PGAPG   VG PG  GP G  G PG RG
Sbjct: 370 PGELGPQGPTGPPGAK--GQEGAHGAPGAAGNPGAPG--HVGAPGPSGPPGSVGAPGLRG 425

Query: 402 LPGE----GFPGPKGEKGSEGPTGPQGLQGL---------------SIKGEKGDIGPVGP 442
            PG+    G  G  GE+GS GP GP+G  G                 ++G  G  GP+G 
Sbjct: 426 TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 485

Query: 443 QGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI 497
           +G  G PGI    GS+G+ GI G  GPPGP GP G +G PGS+G  G  GP GP G  G+
Sbjct: 486 KGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGL 544

Query: 498 GVQGPKGE-------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544
                 G+             PG  GLPG PG  G+ G  GK G  G  G +G  GPP  
Sbjct: 545 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPP-- 602

Query: 545 GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPG 604
           G PGP G  G +GS+G +G  G  G +G +G PG+ G  G PG   PGPPG  G  G  G
Sbjct: 603 GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN--PGPPGADGIAGAAG 660

Query: 605 IPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGL 657
            PG +G PG    GP G QGP G  G PG +G        G PG PG  G PG PGP G 
Sbjct: 661 PPGIQGSPGK--EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 718

Query: 658 RG----VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGS 708
           RG     G TG  G PG RG  G  G  G     G  G  G TG +G  GP GPPG  GS
Sbjct: 719 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 778

Query: 709 QGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGL 764
            G  GE GP G PG KG+ G     GLPG  G  G  G+ G+KG  G+ G PG PG+ G 
Sbjct: 779 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 838

Query: 765 QGPKGDLGL 773
           +G +GD G+
Sbjct: 839 KGERGDPGI 847



 Score =  421 bits (1083), Expect = e-117
 Identities = 262/595 (44%), Positives = 313/595 (52%), Gaps = 74/595 (12%)

Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE---CGKP 303
           PG+ GP G  G+PG+ GE G +G PG     E G +GP G PG KG +G  G     G P
Sbjct: 346 PGEQGPKGEKGDPGLPGEPGLQGRPG-----ELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400

Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPG---DPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
           G  G  G+PGP GP G  G  G+ G PG   + G KG  G +G PGP GP G PGAPG+ 
Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460

Query: 360 --GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGV-----PGERGLPGE 405
               +G  GE G  G PG PGP+G        G PG PG RG  G+     PG  G PG+
Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520

Query: 406 -GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVG-------PQGPMGIPGI-GSQGE 456
            G PG +G  G  GP GP G  GLS     GDI  +        P GP G+PG+ G +G+
Sbjct: 521 KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580

Query: 457 QGIQGPIGPPGPQGPAGQ----GLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGS 508
           +G+ G  G  G +G  G+    GLPG  G  G  G  G RG  G     G QG  G PG 
Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640

Query: 509 IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQ 564
           +G PG PG PG DG AG  G  G+ G+ G EGPPG     G PG  G+EGK+G  G  G 
Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 700

Query: 565 RGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGP 619
            G PG  G  G PG  G  G PG    T   G PGP+G+ G  G+PG +G PG     GP
Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 760

Query: 620 KGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPS 678
            G QGP+GP G PG  G  G PG PGP G P           G  G+KGE G  G PG  
Sbjct: 761 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP-----------GQKGSKGENGSPGLPGFL 809

Query: 679 GPRG-VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-GLP 732
           GPRG  G  G KG  G++G+PG PG PG+    G  GIKG++GP   PG KG  G  G+P
Sbjct: 810 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP---PGGKGQPGDPGIP 866

Query: 733 GQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICG 787
           G KG  G  G  G  G+ G +G PG PG+ G  G +G+   + E + +LI E  G
Sbjct: 867 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE-SPSMETLRRLIQEELG 920



 Score =  416 bits (1068), Expect = e-116
 Identities = 261/625 (41%), Positives = 308/625 (49%), Gaps = 121/625 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G+ G PGP G  G+PG  G  GP   PG  + GE G RG  G+PG  G KG+RG  G PG
Sbjct: 440  GEEGSPGPVGPRGDPGAPGLPGP---PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPG 496

Query: 305  IKGDKGS--------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG-----EPG----- 346
              G +G         PGP GP G +G  G  G PG PGP+G  G  G      PG     
Sbjct: 497  SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLL 556

Query: 347  --------PPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGV 396
                    PPGP G PG PG  G +G+ G+ G+EG  G  G  G  G PG PG  GP+G 
Sbjct: 557  AKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGS 616

Query: 397  PGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQGLS----IKGEKGDIGPVGP 442
             GERG  GE          G PG  G  G+ GP G  G+ G +    I+G  G  GP GP
Sbjct: 617  QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 676

Query: 443  QGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQ 500
            QGP G+PGI G +G++G  G  GPPG  G AG+  PG  G  G  GP G +G  G  G  
Sbjct: 677  QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE--PGLPGPEGARGPPGFKGHTGDSGAP 734

Query: 501  GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG----PPGKGQPGPKGDEGKK 556
            GP+GE G++GLPGQ G+PG+DG  G  G  G  G RGP G    P   G+PGP G  G+K
Sbjct: 735  GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK 794

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEP 612
            GSKG  G  GLPG  GP+G PG  G  G+PG       PG PG KG+RG PGI G KG P
Sbjct: 795  GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPP 854

Query: 613  G----------------LSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPG----------- 644
            G                  + GP+G+ G  GPVG PG  G  G+PG+ G           
Sbjct: 855  GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 914

Query: 645  ---------------------------PRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPG 676
                                        +G PGPPGP G  G+ G  G  GEPG  G  G
Sbjct: 915  IQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG 974

Query: 677  PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736
              GP   G  GPKG+ G KG PG PG       G++GE GP G PG  G  G+   G  G
Sbjct: 975  LEGPS--GPIGPKGERGAKGDPGAPG------VGLRGEMGPPGIPGQPGEPGYAKDGLPG 1026

Query: 737  EHGERGDVGKKGDKGEIGEPGSPGK 761
              G +G+ G  G  G  G PG PG+
Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPGQ 1051



 Score =  395 bits (1016), Expect = e-110
 Identities = 258/614 (42%), Positives = 306/614 (49%), Gaps = 103/614 (16%)

Query: 248 GDPGPPGTHGNPGIKGERGPKGNPG----NAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
           G  GP     +         K  PG    N + GE GE G  G PG +G+ GE+G  G+P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279

Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI---- 359
           G KG+ G PG  G  G RG +G  G  G+ G  G +G++GE G  GP G PG PG     
Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339

Query: 360 -------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-------E 405
                  G+QG KGE+G  G PG PG    G PG+ GP+GP G PG +G  G        
Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGL--QGRPGELGPQGPTGPPGAKGQEGAHGAPGAA 397

Query: 406 GFPGPKGEKGSEGPTGPQGLQGL----------------SIKGEKGDIGPVGPQGPMGIP 449
           G PG  G  G+ GP+GP G  G                    GE+G  GPVGP+G  G P
Sbjct: 398 GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457

Query: 450 GI------GSQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGE--VGQMGPTGPRGP 494
           G+      G  GE G++G  G PGP G  G        G PGS+G+  +G  GP GP GP
Sbjct: 458 GLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP 517

Query: 495 VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGL--PGARG----------PEGPP 542
                 G KG PGS GL   PG PG  G AG+ G + L  PG             P GPP
Sbjct: 518 -----PGDKGSPGSRGL---PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569

Query: 543 G-KGQPGPKGDE---GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPK 597
           G  G PG KGD+   GK G +G +G++G  GP G  G PGI GP G  G     G  G K
Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629

Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPPG 653
           GD+G PG+PGF G PG    GP G  G  G  G PG++G    +G PG  GP GLPG PG
Sbjct: 630 GDQGHPGVPGFMGPPGNP--GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687

Query: 654 PMGLRG-------VGDTGAKGEPGVRGPPGPSGPRGV-------GTQGPKGDTGQKGLPG 699
             G  G        G+ G  GEPG+ GP G  GP G        G  GP+G++G  GLPG
Sbjct: 688 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 747

Query: 700 PPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758
             G PG  G  G  G QGPQG  GP G   +G PG  GE G  G  G+KG KGE G PG 
Sbjct: 748 QEGLPGKDGDTGPTGPQGPQGPRGPPGK--NGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805

Query: 759 PGKQGLQGPKGDLG 772
           PG  G +GP G+ G
Sbjct: 806 PGFLGPRGPPGEPG 819



 Score =  372 bits (956), Expect = e-103
 Identities = 234/530 (44%), Positives = 269/530 (50%), Gaps = 98/530 (18%)

Query: 237  RKIC-ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGE---RGPGGIPGYKG 292
            + +C +C  G PG PG PG  G+ G+ G+ G +G  G  +KGEAG     GP GI G +G
Sbjct: 558  KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG--KKGEAGPPGLPGPPGIAGPQG 615

Query: 293  DKGERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG 346
             +GERG  G+ G KGD+G P      GP G  GP G  GI G  G PG +G  G +G PG
Sbjct: 616  SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 675

Query: 347  PPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPEGVPGERGL 402
            P GP G PG P        GE G+EGR G PGP G     GEPG PGP G  G PG +G 
Sbjct: 676  PQGPSGLPGIP--------GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 727

Query: 403  PGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461
             G+ G PGP+GE G+ G  G +GL      G+ GD GP GPQGP G    G  G+ G  G
Sbjct: 728  TGDSGAPGPRGESGAMGLPGQEGL-----PGKDGDTGPTGPQGPQG--PRGPPGKNGSPG 780

Query: 462  PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521
              G PGP G  GQ   GSKGE G  G  G  GP     +GP GEPG  G+PG+ GVPG+ 
Sbjct: 781  SPGEPGPSGTPGQ--KGSKGENGSPGLPGFLGP-----RGPPGEPGEKGVPGKEGVPGKP 833

Query: 522  GAAGKKGEAGLPGARGPEGPP-GKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580
            G  G KGE G PG +G +GPP GKGQPG  G  G KG  G  G +GLPG  GP G PG  
Sbjct: 834  GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 893

Query: 581  GPFGMPG------------------------------------------TSIPGPPGPKG 598
            G  G PG                                             PGPPGP G
Sbjct: 894  GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 953

Query: 599  DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGP--RGLPGPPGPM 655
              G PG  G  GEPG    G  G++GP GP+G  G +G  G PG PG   RG  GPPG  
Sbjct: 954  KDGLPGRAGPMGEPGRP--GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1011

Query: 656  GLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG 705
            G  G       G PG+ GP G +GP            G  GLPGPPGPPG
Sbjct: 1012 GQPGEPGYAKDGLPGIPGPQGETGP-----------AGHPGLPGPPGPPG 1050



 Score =  344 bits (882), Expect = 3e-94
 Identities = 230/578 (39%), Positives = 277/578 (47%), Gaps = 90/578 (15%)

Query: 266 GPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDK-----GSPGPYGPKG 319
           GP+ +P  N  +G  G  G G             +C  P   G +     G+ GP   + 
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAP--QCSMPKGTGHEFSAALGTQGPADQRA 229

Query: 320 PRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPG 378
                 I      PG K   G  GE G  G  G PG  G IG+QG+ G  G++G  G PG
Sbjct: 230 DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPG 289

Query: 379 PIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSI-----KGE 433
             G   PG  G +G +G  GE GLPG    G +GEKG  GP GP GL G +         
Sbjct: 290 APGF--PGVRGEKGDQGEKGELGLPG--LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 345

Query: 434 KGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTG--- 490
            G+ GP G +G  G+PG     E G+QG  G  GPQGP G   PG+KG+ G  G  G   
Sbjct: 346 PGEQGPKGEKGDPGLPG-----EPGLQGRPGELGPQGPTGP--PGAKGQEGAHGAPGAAG 398

Query: 491 -PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----G 545
            P  P  +G  GP G PGS+G PG  G PG+DG  G+KG AG  G+ GP GP G     G
Sbjct: 399 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458

Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE------PGIMGPFGMPGTSIPGPPGP--- 596
            PGP G +GK G  G +G  GLPGP G KG+      PG  G  G PG  + GPPGP   
Sbjct: 459 LPGPPG-KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP 517

Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQG---------------------PRGPVGAPGLK 635
            GD+G PG  G  G PG   +GP G  G                     P GP G PGL 
Sbjct: 518 PGDKGSPGSRGLPGFPG--PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL- 574

Query: 636 GDGYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690
               PG  G +G+PG PG  G  G     G  G  G PG+ GP G  G RG  G  G KG
Sbjct: 575 ----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 630

Query: 691 DTGQKGLPGPPGPPG-------------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKG 736
           D G  G+PG  GPPG              G  GI+G  G +G PGP+G  G  G+PG++G
Sbjct: 631 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690

Query: 737 EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774
           + G  G  G  G+ G+ GEPG PG +G +GP G  G T
Sbjct: 691 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 728



 Score =  266 bits (680), Expect = 8e-71
 Identities = 179/451 (39%), Positives = 213/451 (47%), Gaps = 95/451 (21%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG+PGPPG  G  G  G  G +G+PG  ++G  G +GP G+PG  G++G+ G  GKPG
Sbjct: 642  GPPGNPGPPGADGIAGAAGPPGIQGSPG--KEGPPGPQGPSGLPGIPGEEGKEGRDGKPG 699

Query: 305  IKGDKGS------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
              G+ G       PGP G +GP G +G TG  G PGP+G  G  G PG  G  G  G  G
Sbjct: 700  PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG 759

Query: 359  -IGQQGIKGERGQEGR------PGAPGPIGV----------GEPGQPG---PRGPEGVPG 398
              G QG +G RG  G+      PG PGP G           G PG PG   PRGP G PG
Sbjct: 760  PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819

Query: 399  ERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG----IGS 453
            E+G+PG EG PG  GE G +G  G  G     IKG+KG  G  G  G  GIPG     G 
Sbjct: 820  EKGVPGKEGVPGKPGEPGFKGERGDPG-----IKGDKGPPGGKGQPGDPGIPGHKGHTGL 874

Query: 454  QGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEV----------------------------- 483
             G QG+ G  GP GP GP GQ G PG +GE                              
Sbjct: 875  MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934

Query: 484  ---------GQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLP 533
                     G+ GP GP G  G+ G  GP GEPG    PGQ G+ G  G  G KGE G  
Sbjct: 935  PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAK 991

Query: 534  GARGPEGPPGKGQPGPKGDEGKKGSKG--NQGQRGLPGPEG---PKGEPGIMGPFGMPGT 588
            G  G  G   +G+ GP G  G+ G  G    G  G+PGP+G   P G PG+ GP      
Sbjct: 992  GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP------ 1045

Query: 589  SIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
              PGPPG                PG +++GP
Sbjct: 1046 --PGPPGQCDPSQCAYFASLAARPG-NVKGP 1073



 Score =  253 bits (647), Expect = 5e-67
 Identities = 161/381 (42%), Positives = 182/381 (47%), Gaps = 66/381 (17%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            E   G PG PG PG  G PG+ G  G +G PG   KG  G+ G  G  G  G  G  G+ 
Sbjct: 692  EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG--FKGHTGDSGAPGPRGESGAMGLPGQE 749

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
            G PG  GD G  GP GP+GPRG  G  G PG PG  G  G  G+ G  G  GSPG PG  
Sbjct: 750  GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 809

Query: 360  ------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKG 412
                  G+ G KG  G+EG PG PG  G  GE G PG +G +G PG +G PG+  PG  G
Sbjct: 810  GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD--PGIPG 867

Query: 413  EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG------------------IGSQ 454
             KG  G  GPQGL      GE G +GP GP G  G PG                  +G Q
Sbjct: 868  HKGHTGLMGPQGL-----PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 922

Query: 455  GE------------------QGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPV 495
             E                  QG  GP GPPG  G  G+  P G  G  GQ G  GP GP+
Sbjct: 923  LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPI 982

Query: 496  GIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGK 555
                 GPKGE G+ G PG PGV       G +GE G PG  G  G PG  + G  G  G 
Sbjct: 983  -----GPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGP 1030

Query: 556  KGSKGNQGQRGLPGPEGPKGE 576
            +G  G  G  GLPGP GP G+
Sbjct: 1031 QGETGPAGHPGLPGPPGPPGQ 1051



 Score =  107 bits (266), Expect = 8e-23
 Identities = 88/241 (36%), Positives = 109/241 (45%), Gaps = 35/241 (14%)

Query: 548 GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPG 607
           GP+ D  +   +G QG  G       +G   ++     P +  P    PKG        G
Sbjct: 172 GPRTDPWENVDQGAQGACG-------RGNTSVL-----PSSVAPQCSMPKGT-------G 212

Query: 608 FKGEPGLSIRGPKGVQGPR------GPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-V 660
            +    L  +GP   +             APGLK     G PG RG  G PG  GLRG +
Sbjct: 213 HEFSAALGTQGPADQRADARASCILAAKTAPGLKQ--LNGEPGERGEDGLPGKPGLRGEI 270

Query: 661 GDTGAKGEPGVRGPPG-PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQG 719
           G+ G  G PG +G  G P  P   G +G KGD G+KG  G PG  G   +G KGE GP G
Sbjct: 271 GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKG--DRGEKGEAGPAG 328

Query: 720 FPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776
            PG  GT     P  +   GE+G  G+KGD G  GEPG    PG+ G QGP G  G   +
Sbjct: 329 PPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 387

Query: 777 E 777
           E
Sbjct: 388 E 388



 Score = 66.6 bits (161), Expect = 1e-10
 Identities = 40/104 (38%), Positives = 45/104 (43%), Gaps = 14/104 (13%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK----------- 291
            E G PG  G  G  G  G KGERG KG+PG    G  GE GP GIPG             
Sbjct: 966  EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP 1025

Query: 292  ---GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGD 332
               G +GE G  G PG+ G  G PG   P        +   PG+
Sbjct: 1026 GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGN 1069


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score =  433 bits (1114), Expect = e-121
 Identities = 290/652 (44%), Positives = 341/652 (52%), Gaps = 135/652 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPG------------YK 291
            GD GD GP G  G+PG+ G  GP G PG     G  G  GP GIPG             K
Sbjct: 654  GDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIK 713

Query: 292  GDKGERG---ECGKPGIKGDKGSPGPYGPKGPR------------GIQGITGPP------ 330
            GDKGE+G   E G+PG  GDKG+ G  GP G R            G+QG +GPP      
Sbjct: 714  GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFP 773

Query: 331  ---------GDPGPKGFQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAP 377
                     G  GPKG  GN+G PGPPG  G+ G  G     G+ G +G+ GQ+G  G P
Sbjct: 774  GDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP 833

Query: 378  GPIGV-GEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKG 432
            GP G+ GE G  G  G  G  G  GLPGE    G  G KGE+GS GP GPQG +G  + G
Sbjct: 834  GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKG--VMG 891

Query: 433  EKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMG 487
              G  G  GP GP+G+PG +G++G  G QGP G  G +GP G    QG+ G+KGE G  G
Sbjct: 892  YPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQG 951

Query: 488  PTGPRGPVG----IGVQGPKGEPGSIGLPGQP---GVPGEDGAAGKKGEAGLPGARGPEG 540
              GP G +G     G +G +G+PG  GLPG     G+PGE G  G +G+ G PG  G EG
Sbjct: 952  KRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEG 1011

Query: 541  PPG-------KGQPGPKGD---------------------------EGKKGSKGNQGQRG 566
            PPG       +G+PG KGD                           +GK G KG  G RG
Sbjct: 1012 PPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071

Query: 567  LPGPEGPKGE---PGIMGPFGMPG-TSIPGP------------PGPKGDRG--GP-GIPG 607
            LPG +G KGE   PGI+GP G  G T +PGP            PG KGD+G  GP G  G
Sbjct: 1072 LPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVG 1131

Query: 608  FKGEPG-LSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665
             +G PG +   GPKG +G RG VG  GL G DG PG+PG RG  G PGP GL   G  G 
Sbjct: 1132 SRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGL--PGPKGE 1189

Query: 666  KGEPG----VRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720
            KG PG    V GPPGP G P  VG QG +G+ G +G  G  G PG   +G  G+QGP G 
Sbjct: 1190 KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL--RGATGQQGPPGE 1247

Query: 721  PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            PG +G       G KGE G  G+ GKKG  G  G+PG PG QGL GPKG  G
Sbjct: 1248 PGDQGEQ-----GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294



 Score =  424 bits (1091), Expect = e-118
 Identities = 270/641 (42%), Positives = 330/641 (51%), Gaps = 113/641 (17%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERGPGGIPGYKGDKG 295
            ++G  G PGP G  G PG+ G +GPKG+PG +       +KG+ G  G  G PG +GDKG
Sbjct: 511  KRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKG 570

Query: 296  ERGECGKPGIKGDKGSPG---PYGPKGPRGIQGITGPPGDPGPKGFQG---NKGEPGPPG 349
             +G  G PG+ G++G PG     G  G  G QG+ GP G+PGPKG QG   + GE G  G
Sbjct: 571  LKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630

Query: 350  PYGSPGAPGI-GQQGIK---------GERGQEGRPGAPGPI-GVGEPGQP---------G 389
            P G  G PGI G++G K         G+RG  G  G+PG + G G PG P         G
Sbjct: 631  PEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG 690

Query: 390  PRGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGI 448
            P GP G+PG  GL G +G PG KG+KG +G  G  G  G    G+KG +G  GP G  G 
Sbjct: 691  PIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG--YPGDKGAVGLPGPPGMRGK 748

Query: 449  PG-IGSQGEQGIQGPIGPPGPQG-PAGQGLPGS------KGEVGQMGPTGP--------- 491
             G  G  G+ G+QGP GPPGP+G P   G+PG       KG +G  GP GP         
Sbjct: 749  SGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE 808

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQ 546
             GP+G  G  GP+G+PG  G  G+PG  G  G  G +G  G  G  GP G PG+    G 
Sbjct: 809  EGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868

Query: 547  PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGG 602
             G KG+ G  G  G QG++G+ G  GP G PG +GP G+PG       PG  GPKG RG 
Sbjct: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928

Query: 603  PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLPGP------ 651
             G  G  GE G+   +G KG QG RGP G  G  G+    G+ G PG +GLPG       
Sbjct: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988

Query: 652  PGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG----------VGTQGPKGDTGQKGLPGP 700
            PG  GLRG+ GD G  GE G+ GPPG  G  G          VGT G  G TG+ GL G 
Sbjct: 989  PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048

Query: 701  PGPPG----YGSQGIKGEQGPQGFPGPKGTMGH-------------------------GL 731
            PG PG     G  G+KG  G +G PG  G  G                          G+
Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGI 1108

Query: 732  PGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            PGQ+G  G++GD G+ G  GE+G  G PGK G  GPKG  G
Sbjct: 1109 PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARG 1149



 Score =  417 bits (1073), Expect = e-116
 Identities = 273/633 (43%), Positives = 331/633 (52%), Gaps = 107/633 (16%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGER---------GPKGNPGNAQKGEAGERGPGGIPGYK 291
            E  KG  G+ GPPG  G  G +GE          GP+G PG  QKG AGE GP G+ G  
Sbjct: 785  EGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG--QKGYAGEPGPEGLKGEV 842

Query: 292  GDKGERGECGKP---------------GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP- 335
            GD+G  G+ G+                G KG++GSPGP GP+G +G+ G  GPPG PGP 
Sbjct: 843  GDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPI 902

Query: 336  -----KGFQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-VGEP 385
                  G  G +G PG  GP G  G+ G    +G+QGI+G +G++G  G  GP G +G+ 
Sbjct: 903  GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKT 962

Query: 386  GQPGPRGPEGVP---------GERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLS 429
            G PG RG +G P         G+RGLPGE       G  GP GE G EGP G +G  GL 
Sbjct: 963  GNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQ 1022

Query: 430  IK-GEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484
             + G KGD+G  G  G  G PG+    G+ GE+G+QG  G  G   P G+GLPG  GE G
Sbjct: 1023 GEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV--PGGRGLPGEDGEKG 1080

Query: 485  QMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543
            +MG  G  GP+G  G  G  G  G +G+PGQ G PG+ G  G+ G  G  G+RGP G  G
Sbjct: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG 1140

Query: 544  KGQP----------------GPKGDEGKKGSKGNQGQ---RGLPGPEGPKGEPG----IM 580
            K  P                GP G+ G  G +G+QGQ    GLPGP+G KG PG    ++
Sbjct: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL 1200

Query: 581  GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQGP---RGPVGAPGLKG 636
            GP G  G   PGP G +G+RG PG  G+KG  G+  +RG  G QGP    G  G  GLKG
Sbjct: 1201 GPPGPRGE--PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKG 1258

Query: 637  D-------GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG-VGTQG 687
            +       G  G PGP G PG PG  GL G  G  G  G  G+ G PG  GP G  G  G
Sbjct: 1259 ERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPG 1318

Query: 688  PKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG 739
             +G  G+ GL G PGPPG        GS GI+G +G QG PG  G  G  G  G +G+ G
Sbjct: 1319 IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQG 1378

Query: 740  ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              GD G KG  GE G  G  G QG  GPKG  G
Sbjct: 1379 PCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEG 1411



 Score =  404 bits (1037), Expect = e-112
 Identities = 272/651 (41%), Positives = 338/651 (51%), Gaps = 101/651 (15%)

Query: 245  GDPGDPGPPGTHGNPGIKG------ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            G+ G PGPPG  G  G +G      E GP+G PG  QKG AGE GP G+ G  GD+G  G
Sbjct: 792  GNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG--QKGYAGEPGPEGLKGEVGDQGNIG 849

Query: 299  ECGKPGI---------------KGDKGSPGPYGPKGPRGIQGITGPPGDPGP------KG 337
            + G+ G                KG++GSPGP GP+G +G+ G  GPPG PGP       G
Sbjct: 850  KIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG 909

Query: 338  FQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG 392
              G +G PG  GP G  G+ G    +G+QGI+G +G++G  G  GP G +G+ G PG RG
Sbjct: 910  HVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969

Query: 393  PEGVPG---------ERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLSIK-GEKG 435
             +G PG         +RGLPGE       G  GP GE G EGP G +G  GL  + G KG
Sbjct: 970  FQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKG 1029

Query: 436  DIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGP 491
            D+G  G  G  G PG+    G+ GE+G+QG  G  G   P G+GLPG  GE G+MG  G 
Sbjct: 1030 DVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV--PGGRGLPGEDGEKGEMGLPGI 1087

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPK 550
             GP+G  G  G  G  G +G+PGQ G PG+ G  G+ G  G  G+RGP G  GK   GPK
Sbjct: 1088 IGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS--GPK 1145

Query: 551  GDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI----- 605
            G    +G++G  G  GL GP+G  G PG  G  G PG S  G PGPKG++G PG      
Sbjct: 1146 G---ARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPS--GLPGPKGEKGYPGEDSTVL 1200

Query: 606  --PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-- 660
              PG +GEPG     P G QG RG  GA G KG  G PG+ G  G  GPPG  G +G   
Sbjct: 1201 GPPGPRGEPG-----PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQG 1255

Query: 661  --GDTGAKGEPGVRGPPGPSGPRGV----------GTQGPKGDTGQKGLPGPPGPPGY-- 706
              G+ G++G  G +G PGPSG  G+          G QG  G  G  G PG  GPPG   
Sbjct: 1256 LKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG 1315

Query: 707  --GSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPG 760
              G +G  G  G  G PGP G  G     G PG +G  GE+G  G+ G +G+ G  G+ G
Sbjct: 1316 LPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQG 1375

Query: 761  KQGLQGPKGDLGLTKEEIIKLITEICGC-GPKCKETPLELVFVIDSSESVG 810
             QG  G  G  G   E  ++ +T   G  GPK  E    +V +      +G
Sbjct: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIG 1426



 Score =  399 bits (1024), Expect = e-110
 Identities = 262/590 (44%), Positives = 307/590 (52%), Gaps = 92/590 (15%)

Query: 265  RGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPR--- 321
            RGPKG+ G       G  GP GIPG  G +G RG    PG  G+ G PG  GPKGP+   
Sbjct: 488  RGPKGDTG-----PPGPPGPAGIPGPSGKRGPRGI---PGPHGNPGLPGLPGPKGPKGDP 539

Query: 322  ---------------GIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-IGQQGIK 365
                           G+ G+ GPPG  G KG +G+ G PG PG  G PG  G IG  G  
Sbjct: 540  GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599

Query: 366  GERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEK 414
            G +G  G  G PGP G        GE GQ GP G  G+PG RG  G    +GFPG  G++
Sbjct: 600  GRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659

Query: 415  GSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469
            G  G  G  GL G        G +G +GPVGP GP GIPG +G  G +G+ G  G  G Q
Sbjct: 660  GPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719

Query: 470  GPAGQ----GLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPGVP 518
            G AG+    G PG KG VG  GP G RG  G        G+QGP G PG  G PG  G+P
Sbjct: 720  GTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779

Query: 519  GEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQRGL---PGPE 571
            G++G  G K   GL G RGP GPPG    +G+ GP G  G+ G +G  GQ+G    PGPE
Sbjct: 780  GQNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPE 836

Query: 572  GPKGEPGIM---------GPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPK 620
            G KGE G           GP G+PG   + G  G KG+RG PG  G +GE G +   GP 
Sbjct: 837  GLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPP 896

Query: 621  GVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPS 678
            GV GP GP+G PG  G  G PG  GP+G  G  GP GL G  G  GAKGE G +G  GP 
Sbjct: 897  GVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956

Query: 679  GPRG-------------VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPK 724
            G  G              G QG  G TG +GLPG PG  G  G  G  GE G +G PG +
Sbjct: 957  GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016

Query: 725  GTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G  G  G PG KG+ G  G VG  G+ G  GEPG+PG++GLQG  G  G+
Sbjct: 1017 GESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV 1066



 Score =  398 bits (1023), Expect = e-110
 Identities = 247/593 (41%), Positives = 313/593 (52%), Gaps = 81/593 (13%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN-------AQKGEAGERGPGGIPGYKGDKGER 297
            G  G  GPPG+ G  G +G RGP G  G         +KG+ G+RGP G+ G  G+ GER
Sbjct: 909  GHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
            G  GKPG++G  GS G  G  G  G++G+ G  G PG  G +G  G  G  G  G PGA 
Sbjct: 969  GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028

Query: 358  G----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-------- 405
            G     G  G  GE G  G PGAP     GE G  G  G +GVPG RGLPGE        
Sbjct: 1029 GDVGTAGSVGGTGEPGLRGEPGAP-----GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083

Query: 406  --GFPGPKGEKGSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPG----IG 452
              G  GP G  G  G  GP+G+ G+         KG+KG IGP G  G  G PG     G
Sbjct: 1084 LPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG 1143

Query: 453  SQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-----------IGVQ 500
             +G +G +G +G  G  GP G+ G+PG +G  GQ GP+G  GP G           +G  
Sbjct: 1144 PKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPP 1203

Query: 501  GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK 559
            GP+GEPG +G  G+ G PG +G  G  G  GL GA G +GPPG+ G  G +G +G++GS+
Sbjct: 1204 GPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263

Query: 560  GNQGQRGLPGPEGPKGEP---GIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEP 612
            GN+G++G PGP G  G P   G++GP G+ G      I G PG  G  G  G+PG +G P
Sbjct: 1264 GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGP 1323

Query: 613  GLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPR---GLPGPPGPMGLRG----VGDTGA 665
            G +  G  G  GP G  G+ GL G   PG+ GP+   GLPG PG  G RG     GD G 
Sbjct: 1324 GRT--GLAGAPGPPGVKGSSGLPGS--PGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379

Query: 666  KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPK 724
             G+PG++G PG  G +G+        TG +G PGP GP G  G  GI G +GP G  G  
Sbjct: 1380 CGDPGLKGQPGEYGVQGL--------TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431

Query: 725  GTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            G +G     G  G+ G  GE+G  G+ G +G  G+PG PG  G  GP+  + +
Sbjct: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDI 1484



 Score =  372 bits (956), Expect = e-103
 Identities = 238/523 (45%), Positives = 279/523 (53%), Gaps = 69/523 (13%)

Query: 305 IKGDKGSPGPYGPKGPRGIQGIT---GPPGDPGPKGFQGNKGEPGPPGPYGSPG-APGIG 360
           ++G KG  GP GP GP GI G +   GP G PGP G  G  G PGP GP G PG +PG  
Sbjct: 487 LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG-- 544

Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------EGFPGPKG 412
            Q + GE+G +G  G  GP G+ G+ G  G  G  G+PGE+G+PG        G+PG +G
Sbjct: 545 -QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQG 603

Query: 413 EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGP 468
             G EG  GP+G QG    G  G+ G +GP+G  GIPGI    G +G QG  G  G  GP
Sbjct: 604 LAGPEGNPGPKGAQGFI--GSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGP 661

Query: 469 QG-------PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521
            G         G G PG  G  G +GP GP GP GI   GP G  G+ GLPG  G  GE 
Sbjct: 662 AGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQ 719

Query: 522 GAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMG 581
           G AG+ GE G PG +G       G PGP G  GK G  G  G  GL GP GP G  G  G
Sbjct: 720 GTAGELGEPGYPGDKG-----AVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPG 774

Query: 582 PFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP 640
             G+PG + P GP G  G+RG PG PG KG  G    GP G  G  GP G PG K  GY 
Sbjct: 775 DIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQG--EEGPIGAFGELGPRGKPGQK--GYA 830

Query: 641 GVPGPRGLP------------GPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQG 687
           G PGP GL             G  GP+GL G VG TG+ GE G RG PGP GP+  G +G
Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQ--GEKG 888

Query: 688 PKGDTGQKGLPGPPGP---PGY-GSQGIKGEQGPQGFPGPKGTMG-------HGLPGQKG 736
             G  G  G+PGP GP   PG+ G++G  G QGP+G  G +G  G        G  G+KG
Sbjct: 889 VMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKG 948

Query: 737 EHGERGD---VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           + G+RG    +GK G+ GE G  G PG QGL G  GD GL  E
Sbjct: 949 DQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991



 Score =  309 bits (791), Expect = 1e-83
 Identities = 209/491 (42%), Positives = 259/491 (52%), Gaps = 79/491 (16%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGECGKP 303
            G+ G  GPPGT G  G++GE G KG+ G A   G  GE G  G PG  G++G +G+ G  
Sbjct: 1005 GEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLK 1064

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGD------PGPKGF------------QGNKGEP 345
            G+ G +G PG  G KG  G+ GI GP G       PGP+G             +G+KG+ 
Sbjct: 1065 GVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQI 1124

Query: 346  GPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP 403
            GP G  GS G PG IG+ G KG RG  G  G  G +G  GEPG PG RG +G PG  GLP
Sbjct: 1125 GPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLP 1184

Query: 404  GEGFPGPKGEKGSEG-------PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQG 455
            G     PKGEKG  G       P GP+G  G +  +GE+G+ G  G +G +G+PG+  +G
Sbjct: 1185 G-----PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL--RG 1237

Query: 456  EQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKG------ 504
              G QGP G PG QG  G +G  GS+G  G+ G  GP G  GI    G+ GPKG      
Sbjct: 1238 ATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297

Query: 505  ------EPGSIGLPGQPGVPGEDGAAGK------------KGEAGLPGARGPEGPPGK-- 544
                   PG IG PG+ G+PG  G  G+            KG +GLPG+ G +GP G+  
Sbjct: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357

Query: 545  --GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG 602
              GQPG +G  G +G++G+QG  G PG +G  GE G+ G  G  G   PGP GP+GD G 
Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQG--FPGPKGPEGDAGI 1415

Query: 603  PGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLP---GPPGP 654
             GI G KG  G     GP G +G  GP G  G +G+    G  G  GPRG P   GPPG 
Sbjct: 1416 VGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGA 1475

Query: 655  MGLRGVGDTGA 665
             G R   D  A
Sbjct: 1476 PGPRKQMDINA 1486



 Score =  227 bits (578), Expect = 5e-59
 Identities = 150/362 (41%), Positives = 182/362 (50%), Gaps = 73/362 (20%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G+ G  GPPG  G  G KG RG +G  G+   G  G  G  GIPGY+G +G+ G  G PG
Sbjct: 1128 GEVGSRGPPGKIGKSGPKGARGTRGAVGHL--GLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185

Query: 305  IKGDKGSPG-------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
             KG+KG PG       P GP+G  G  G  G  G+PG +G++G+ G PG  G  G  G P
Sbjct: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPP 1245

Query: 358  GI----GQQGIKGERGQEG---RPGAPGPIGV-------------------------GEP 385
            G     G+QG+KGERG EG   + GAPGP G                          G P
Sbjct: 1246 GEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNP 1305

Query: 386  GQPGPRGPEGVPGERGLPGE----GFPGPKGEKGS---------EGPTGPQGLQGL-SIK 431
            G+ GP G +G+PG RG PG     G PGP G KGS         +GP G QGL G   I+
Sbjct: 1306 GKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365

Query: 432  GEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEV 483
            G++G  G  G QGP G PG+       G QG  G QG  GP GP+G AG  G+ G KG +
Sbjct: 1366 GKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI 1425

Query: 484  GQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLP 533
            G  G TGP G  GI          G +G +GE G  G  GQPG PG  GA G + +  + 
Sbjct: 1426 GHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDIN 1485

Query: 534  GA 535
             A
Sbjct: 1486 AA 1487



 Score =  222 bits (565), Expect = 2e-57
 Identities = 133/296 (44%), Positives = 164/296 (55%), Gaps = 29/296 (9%)

Query: 243  EKGDPGDP----GPPGTHGNPGIKGERGPKGNPGN----------AQKGEAGERGPGGIP 288
            EKG PG+     GPPG  G PG  G++G +G PG             +G  G++GP G P
Sbjct: 1189 EKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248

Query: 289  GYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348
            G +G++G +GE G  G KG KG+PGP G  G  G+QG+ GP G  G  G  G  G PG  
Sbjct: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308

Query: 349  GPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGE-G 406
            GP G  G P     GI+G  G+ G  GAPGP GV G  G PG  G +G  GE+GLPG+ G
Sbjct: 1309 GPPGKQGLP-----GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPG 1363

Query: 407  FPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGP 465
              G +G +G++G  GP G  GL  KG+ G+ G  G  G  G PG  G +G+ GI G  GP
Sbjct: 1364 IQGKRGHRGAQGDQGPCGDPGL--KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGP 1421

Query: 466  PGPQGPAGQGLP-GSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPG 516
             GP G  G   P G +G +G  G TGPRG  G     G QGP+G+PG  G PG PG
Sbjct: 1422 KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477



 Score =  166 bits (421), Expect = 9e-41
 Identities = 108/248 (43%), Positives = 128/248 (51%), Gaps = 30/248 (12%)

Query: 241  ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300
            E  KG  G PGP G  G PG++G  GP        KG  G  G  GI G  G  G  G+ 
Sbjct: 1263 EGNKGKKGAPGPSGKPGIPGLQGLLGP--------KGIQGYHGADGISGNPGKIGPPGKQ 1314

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359
            G PGI+G  G  G  G  GP G++G +G PG PG +G +G +G PG PG  G  G  G  
Sbjct: 1315 GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQ 1374

Query: 360  GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEG 418
            G QG  G+ G +G+PG  G  G+ G  G PGP+GPEG  G  G+      GPKG  G  G
Sbjct: 1375 GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI-----SGPKGPIGHRG 1429

Query: 419  PTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPG 478
             TGP G +G+        IGP G  GP G  G   +GE G QGP G PGP GP     PG
Sbjct: 1430 NTGPLGREGI--------IGPTGRTGPRGEKGF--RGETGPQGPRGQPGPPGP-----PG 1474

Query: 479  SKGEVGQM 486
            + G   QM
Sbjct: 1475 APGPRKQM 1482



 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 46/112 (41%), Positives = 61/112 (54%), Gaps = 15/112 (13%)

Query: 666 KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725
           +G  G  GPPGP GP G+   GP G  G +G+PGP G PG    G+ G +GP+G PG   
Sbjct: 488 RGPKGDTGPPGPPGPAGI--PGPSGKRGPRGIPGPHGNPGL--PGLPGPKGPKGDPG--F 541

Query: 726 TMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
           + G  +PG+KG+ G           G +G PG  G +GL+G  G  GL  E+
Sbjct: 542 SPGQPVPGEKGDQGL---------SGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  431 bits (1109), Expect = e-120
 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%)

Query: 244  KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295
            +GDPG PGPPG  G PG  I+G RG +G PG      Q+G  G+ GP G PG  G    G
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
              GE G PGI G +G  GP G +G  G  GI GPPG+ G  G  G  G  GPPGP G+PG
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 356  APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389
             PG  G  GI G +GQ G PGA         PGP  +                G PG+ G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 390  PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435
             RG  G+PG +GL G     G PGP+G+ GS G  G  GL+G+            KG++G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 436  DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             +G  G  G  G+PGI G QG++G  G      PGP GP G  GLPG  G+ G+MG  GP
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543
             G +G  G +G  G PGS GLPG+PG  G+ G  G KG  G PG RGP G PG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 544  ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569
                              KG+       PGP+G+ G +G+KG++G  G PG         
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 570  ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620
               P GP G  G  GP G+PG  IPG  G   P G RG PG PG  G PG   + I+G K
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 621  GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675
            G  G  GP G PG  GD  P    G PG  GLPGP G  G +G  G  G KG PG  G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 676  GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728
            GP GP  +G +GP G  G  G      LPG PGPPG  G  G++GE GP G PG  G  G
Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 729  -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              G PG+ G+ G  G  G+KG+KG  GEPG  G  GL G KG  G
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  422 bits (1084), Expect = e-117
 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            EKGD G PGPPG  G  G +G  GP G PG+      G RG  G PG KG KGERG  GK
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 303  --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344
                          PG+ G  G PGP G     KGP G  G+ G  G PG  G  G KGE
Sbjct: 412  DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471

Query: 345  PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391
            PG         PGP G PG PG+ G +GI G +G    +G PG+PG  G+ G PG PG +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 392  GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433
            G  G+ GE+G          +PG+    G PG KG  G  G  G +GL G    L++ GE
Sbjct: 532  GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591

Query: 434  KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484
            KGD GP G         P GP G PG G QGE G+QG  G PG  GP G+   G +GE+ 
Sbjct: 592  KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649

Query: 485  QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528
                  GP GP GP G  G QGP G PGS+G  G PG+PG D           G  G KG
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 529  EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579
            + G PG +G  G PGK G+PG  G  G  G+K        G  G  G PG  G  GE G 
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 580  MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623
            +G  G+PG  +PG P      GP+GD G PG PG +G PG  I GP+G Q          
Sbjct: 770  IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 624  --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675
                    GP+G  G PGL   G+PG  G  G+PG  G MG   +G  G  G PG+ GPP
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885

Query: 676  GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724
            G  G       P  +G  GP G+ G  G  G PG PG     G+ G KGEQG +G PGP 
Sbjct: 886  GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944

Query: 725  GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774
              + H + G KGE G +G  G  G+KG  G PG PG +GL+         GP+GDLG T
Sbjct: 945  SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002



 Score =  411 bits (1057), Expect = e-114
 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%)

Query: 240  CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293
            C  + G+PG PG PG    PG KGE      G  G PG   ++G +GE G  G+PG  G 
Sbjct: 722  CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
             G  G  G  G +GD G PGP G +GP G  I+G  G  G PG  G +G +G  G  GP 
Sbjct: 779  PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404
            G PG PG+ + G  GE G  G PG  G +G        G PG  GP G +GV G  G PG
Sbjct: 839  GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898

Query: 405  E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456
              G PGP G  G+ G  G  G+ G  +KG++G  G  G QG  G PG       IG +GE
Sbjct: 899  AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 457  QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514
             G++G  G PG +G  G  G+PG KG  G  GP GP GP G +G  G  GEPG  G+PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 515  PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556
             G  G  G+ GK+G  G PG  G  G PG                   G PGP GD G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600
            G  G +G+ G PGP G  G  G  G  G PG+  +PG PGP GD               R
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 601  GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648
            G PG+PGF G PG + IRG +G  G  GP G           PG +G+ G  G  G RG 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 649  PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701
            PG PG  G +G +GD G +G  G+ G PGP G      P   G +GP G  G  G PGPP
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 702  GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751
            GPPG    GIKG++G  G PGPKG  G           G PG  G  G RGD G +G  G
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 752  EIGEPGSPGKQGLQGPKGDLG 772
              GE G+PG  G  GP G +G
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337



 Score =  408 bits (1048), Expect = e-113
 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298
            ++G PG PG  G  G PG KGE+G KGNPG ++     G+ GE G  G  G  G+KG RG
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347
              G PG+KG KG PGP GP GPRG  G TG PG+PG +G     GN G PG         
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 348  -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403
             PG  G PG PGI G QG KGE G  EG RPG PGP   G+PG PG  G +G  G+ G P
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091

Query: 404  G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451
            G       EG PG  G  G  G  GP G   L  KG KG +GP G +GP G+PG      
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 452  -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486
                 G QG  GI GP G          PPGP+G  G           G PG  G  G M
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 487  GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545
            G  GPRGP GI G  GP G PG+I       +PG+ G  G  G  G PGA GP GPPG  
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262

Query: 546  QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605
              G KGD   KGS G+ G +G PG  G  G PG +G  G PG  +PGP G  G +G PG+
Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317

Query: 606  PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665
             G KG PG    G  G  GP GP G PG++GD  PG      LPG PGP         G 
Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365

Query: 666  KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724
             GEPG++G PGP GP G +G  GP+G  G+ G PG PGP G      KG +G +G PGP 
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420

Query: 725  GTMGHGLPGQKGEHGERG 742
            G+   GLPG KG+ G+ G
Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436



 Score =  397 bits (1021), Expect = e-110
 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287
           C   KG+ G PG PGT G PGI G  G KG  G   K            G  G  GP G+
Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184

Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333
           PG  G  G  G  G PG  G  G+ GP GP           KG RG++G+TGPPG P   
Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244

Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371
                         G KG +G  GEPGPPGP G P        GAP  G  G++G+ G++
Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302

Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411
           G PG PG  GV G  G PG  G +G+ G++G  G                   EG PGP 
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452
           G +G+ GP GP G  G+                   +KG KG+ G  G +  MG PG  G
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421

Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498
             G  G+ G  GPPGP G        P   GLPG  G  G  G  GP+G  G+       
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558
           + GP G PG  GL G  G+PG  GAAG KG  G PG  G  G P  G PG +GD G KG 
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539

Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613
           KG     +GQ G+PG  G +G+PG  G  G+PGT  + G PGPKG+    G  G +G PG
Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668
               G  G  GP GP G PG    G PG+ G +G+PG PGP G  G        T   G 
Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657

Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724
           PG  GPPG  GP+G  G  G  G  G  GLPGP   PG PG G  G  G +G QGFPG K
Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717

Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755
           G++G              GLPG KGE         G  G  G++G+ GE GE        
Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 756 -PGSPGKQGLQGPKGDLG 772
            PG+PG +GL GP+GD G
Sbjct: 778 LPGTPGNEGLDGPRGDPG 795



 Score =  390 bits (1002), Expect = e-108
 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
           C+  KG+ G+ G PG  G+PG KG  GP+G P     G  G +G  G+PG  G KG RG 
Sbjct: 41  CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95

Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
            G PG  G  G PG  G  GP G+ G+      PG  G +G +G PG PG  G PG PG 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149

Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406
            G +G KG            +G  G PGAPGP G+ G PG PGP GP G PG  G PG  
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439
            P            G KGE+G +G TGP G  G  I               KG+KG +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457
            GP GP G+PG                                          +G  G +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498
           G +G IGPPG +GP            +G PG  G  G  GP GP GP G+         G
Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389

Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551
           ++G  G PG  G  G+ G PG+D     G+ G  G  GLPG+ GP GPPG    + GP G
Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449

Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587
           D G  G  G+    G+PG +GPKGEPG++        GP G+PG                
Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636
                 PG PG  G  G PG PG +G+PG        L   G  GV G  G  G PG KG
Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566

Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            DG PG PG +GLPGP G + L G  GD G  G+PG  G PGP+GP G    GP+G+ G 
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719
           +G                             PGPPGPPG+       G  G  G+ G  G
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686

Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
            PGP G  G       G PG KG+ G  G  G  G  G++GEPG PGK GL G KG+
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743



 Score =  390 bits (1001), Expect = e-108
 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%)

Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299
           +KG  G+PGPPG  G PG     E+G  G+PG   +G+ G+ G  G PG +G KG RG  
Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348
              G+ GIKG KG  GP G +GP         +G +G  GPPG  G +G QG  G PG P
Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399
           G  GS  PG  G  G  G+KG +G+ GRP     G PG  G  G PG PG  GP G PG+
Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448
               +G PG+ G PG  G  G  G  GP+G  GL       I G  G  G  G  G  GI
Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502
           P  G QG  G++G  G PG  G P   G PG++G+ G  G  G    P G VG+ G  G 
Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553
           +G+PG  GL G PG PG  G  G KGE  L G +G +GPPG     G PGP G       
Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
           G +G  G QG +G+PG  GP GE G  G   +  T +PGPPGP G  G PG  G  G PG
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660
               G  G  G  GP G PG+ G G+PG PGP+G  G PG  G  G              
Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735

Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719
           G  GAKGEP V  P GP  P   G +G  G+ G+ GLPG PG PG  G++G+ G +G  G
Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795

Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753
            PGP G  G                GL G KG+ G RG  G KGD            GE 
Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 754 GEPGSPGKQGLQGPKGDLG 772
           G PG PG QG  GP G  G
Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874



 Score =  294 bits (752), Expect = 4e-79
 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%)

Query: 243  EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297
            +KG+PG      PGPPG  G+PG+ G+ G KG  G  Q G  G  GP G  G  G  G  
Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 298  GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354
            G  GKPG  GD   KG  G  GP G RG  G+ G PG PGP G +G++G  G PGP G  
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 355  GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402
            G  G+           G QG KG+RG  G PG PG  G +G+ G  GP G EG PG  GL
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229

Query: 403  PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452
            PG          G PG +G  G+ GP GP G   + IKG+KG +G  GP+GP G  G +G
Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289

Query: 453  SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507
              G  G  G  G PGP+G  G QG PG KGE G    +G  GP GP+G  G  G +G+PG
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 508  SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560
            ++      G PG PG PGE G  G+ G  G PG  GP GP GK G+ G  G  G  G KG
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588
            N+G +G PGP G  G PG+ G  G  G+
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437



 Score =  214 bits (544), Expect = 5e-55
 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%)

Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560
           G KGE G  G PG PG PG+ G  G +G   LPG +GP     KG PG  G  G KG +G
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94

Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620
             G  G  G  G  G PG  GP+G+ G  +PG  G KG++G PG+PG  G PG+      
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147

Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670
           G  G +G  GAP          KGD G PG PGP+GLPGPPG  G  G  G  G  G PG
Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718
             GP GP G  G    G KG+ G KGL GPPGPPG               +G KG++G  
Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267

Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           G PGP G  G  LPG+    E G  GD G +G  G+ G PG PG +G++G +G  GL  E
Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 777 EIIK 780
           + IK
Sbjct: 326 DGIK 329



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296
            KG+ G+PG  G+ G PG  G +GP   +G+PG  +     G  G  G  G PG +G+   
Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
                      G  G PG  GP GPRG  G  G PG PGP G +GNKG  G PGP GS G 
Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425

Query: 357  PGIGQQGIKGERGQEGRP 374
            P     G+KG+RG  G P
Sbjct: 1426 P-----GLKGKRGDSGSP 1438



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%)

Query: 245  GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            G  G  GPPG  G+PG      + G  GP G PG  + G  GE GP G PG  G  G RG
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
               KPG  G  G+PGP G KG +G +G  GP G  G  G +G +G+ G P  + + G
Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query: 247  PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306
            PG PGPPGT G PG++GE GP G PGN   G  G RG  G  G  G  G  GE G  G K
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 307  GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338
            G+ G  G  G  G +G +G +G P     +GF
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788
           G  G+KGE G  G  G  G KG  G  G PG QG +G  G  GLT  + ++ I+ + G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814
                 G      P  LV V   S S G + F
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  431 bits (1109), Expect = e-120
 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%)

Query: 244  KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295
            +GDPG PGPPG  G PG  I+G RG +G PG      Q+G  G+ GP G PG  G    G
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
              GE G PGI G +G  GP G +G  G  GI GPPG+ G  G  G  G  GPPGP G+PG
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 356  APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389
             PG  G  GI G +GQ G PGA         PGP  +                G PG+ G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 390  PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435
             RG  G+PG +GL G     G PGP+G+ GS G  G  GL+G+            KG++G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 436  DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             +G  G  G  G+PGI G QG++G  G      PGP GP G  GLPG  G+ G+MG  GP
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543
             G +G  G +G  G PGS GLPG+PG  G+ G  G KG  G PG RGP G PG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 544  ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569
                              KG+       PGP+G+ G +G+KG++G  G PG         
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 570  ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620
               P GP G  G  GP G+PG  IPG  G   P G RG PG PG  G PG   + I+G K
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 621  GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675
            G  G  GP G PG  GD  P    G PG  GLPGP G  G +G  G  G KG PG  G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 676  GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728
            GP GP  +G +GP G  G  G      LPG PGPPG  G  G++GE GP G PG  G  G
Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 729  -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              G PG+ G+ G  G  G+KG+KG  GEPG  G  GL G KG  G
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  422 bits (1084), Expect = e-117
 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            EKGD G PGPPG  G  G +G  GP G PG+      G RG  G PG KG KGERG  GK
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 303  --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344
                          PG+ G  G PGP G     KGP G  G+ G  G PG  G  G KGE
Sbjct: 412  DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471

Query: 345  PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391
            PG         PGP G PG PG+ G +GI G +G    +G PG+PG  G+ G PG PG +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 392  GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433
            G  G+ GE+G          +PG+    G PG KG  G  G  G +GL G    L++ GE
Sbjct: 532  GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591

Query: 434  KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484
            KGD GP G         P GP G PG G QGE G+QG  G PG  GP G+   G +GE+ 
Sbjct: 592  KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649

Query: 485  QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528
                  GP GP GP G  G QGP G PGS+G  G PG+PG D           G  G KG
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 529  EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579
            + G PG +G  G PGK G+PG  G  G  G+K        G  G  G PG  G  GE G 
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 580  MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623
            +G  G+PG  +PG P      GP+GD G PG PG +G PG  I GP+G Q          
Sbjct: 770  IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 624  --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675
                    GP+G  G PGL   G+PG  G  G+PG  G MG   +G  G  G PG+ GPP
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885

Query: 676  GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724
            G  G       P  +G  GP G+ G  G  G PG PG     G+ G KGEQG +G PGP 
Sbjct: 886  GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944

Query: 725  GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774
              + H + G KGE G +G  G  G+KG  G PG PG +GL+         GP+GDLG T
Sbjct: 945  SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002



 Score =  411 bits (1057), Expect = e-114
 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%)

Query: 240  CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293
            C  + G+PG PG PG    PG KGE      G  G PG   ++G +GE G  G+PG  G 
Sbjct: 722  CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
             G  G  G  G +GD G PGP G +GP G  I+G  G  G PG  G +G +G  G  GP 
Sbjct: 779  PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404
            G PG PG+ + G  GE G  G PG  G +G        G PG  GP G +GV G  G PG
Sbjct: 839  GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898

Query: 405  E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456
              G PGP G  G+ G  G  G+ G  +KG++G  G  G QG  G PG       IG +GE
Sbjct: 899  AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 457  QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514
             G++G  G PG +G  G  G+PG KG  G  GP GP GP G +G  G  GEPG  G+PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 515  PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556
             G  G  G+ GK+G  G PG  G  G PG                   G PGP GD G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600
            G  G +G+ G PGP G  G  G  G  G PG+  +PG PGP GD               R
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 601  GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648
            G PG+PGF G PG + IRG +G  G  GP G           PG +G+ G  G  G RG 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 649  PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701
            PG PG  G +G +GD G +G  G+ G PGP G      P   G +GP G  G  G PGPP
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 702  GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751
            GPPG    GIKG++G  G PGPKG  G           G PG  G  G RGD G +G  G
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 752  EIGEPGSPGKQGLQGPKGDLG 772
              GE G+PG  G  GP G +G
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337



 Score =  408 bits (1048), Expect = e-113
 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298
            ++G PG PG  G  G PG KGE+G KGNPG ++     G+ GE G  G  G  G+KG RG
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347
              G PG+KG KG PGP GP GPRG  G TG PG+PG +G     GN G PG         
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 348  -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403
             PG  G PG PGI G QG KGE G  EG RPG PGP   G+PG PG  G +G  G+ G P
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091

Query: 404  G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451
            G       EG PG  G  G  G  GP G   L  KG KG +GP G +GP G+PG      
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 452  -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486
                 G QG  GI GP G          PPGP+G  G           G PG  G  G M
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 487  GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545
            G  GPRGP GI G  GP G PG+I       +PG+ G  G  G  G PGA GP GPPG  
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262

Query: 546  QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605
              G KGD   KGS G+ G +G PG  G  G PG +G  G PG  +PGP G  G +G PG+
Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317

Query: 606  PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665
             G KG PG    G  G  GP GP G PG++GD  PG      LPG PGP         G 
Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365

Query: 666  KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724
             GEPG++G PGP GP G +G  GP+G  G+ G PG PGP G      KG +G +G PGP 
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420

Query: 725  GTMGHGLPGQKGEHGERG 742
            G+   GLPG KG+ G+ G
Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436



 Score =  397 bits (1021), Expect = e-110
 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287
           C   KG+ G PG PGT G PGI G  G KG  G   K            G  G  GP G+
Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184

Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333
           PG  G  G  G  G PG  G  G+ GP GP           KG RG++G+TGPPG P   
Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244

Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371
                         G KG +G  GEPGPPGP G P        GAP  G  G++G+ G++
Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302

Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411
           G PG PG  GV G  G PG  G +G+ G++G  G                   EG PGP 
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452
           G +G+ GP GP G  G+                   +KG KG+ G  G +  MG PG  G
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421

Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498
             G  G+ G  GPPGP G        P   GLPG  G  G  G  GP+G  G+       
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558
           + GP G PG  GL G  G+PG  GAAG KG  G PG  G  G P  G PG +GD G KG 
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539

Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613
           KG     +GQ G+PG  G +G+PG  G  G+PGT  + G PGPKG+    G  G +G PG
Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668
               G  G  GP GP G PG    G PG+ G +G+PG PGP G  G        T   G 
Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657

Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724
           PG  GPPG  GP+G  G  G  G  G  GLPGP   PG PG G  G  G +G QGFPG K
Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717

Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755
           G++G              GLPG KGE         G  G  G++G+ GE GE        
Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 756 -PGSPGKQGLQGPKGDLG 772
            PG+PG +GL GP+GD G
Sbjct: 778 LPGTPGNEGLDGPRGDPG 795



 Score =  390 bits (1002), Expect = e-108
 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
           C+  KG+ G+ G PG  G+PG KG  GP+G P     G  G +G  G+PG  G KG RG 
Sbjct: 41  CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95

Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
            G PG  G  G PG  G  GP G+ G+      PG  G +G +G PG PG  G PG PG 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149

Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406
            G +G KG            +G  G PGAPGP G+ G PG PGP GP G PG  G PG  
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439
            P            G KGE+G +G TGP G  G  I               KG+KG +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457
            GP GP G+PG                                          +G  G +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498
           G +G IGPPG +GP            +G PG  G  G  GP GP GP G+         G
Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389

Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551
           ++G  G PG  G  G+ G PG+D     G+ G  G  GLPG+ GP GPPG    + GP G
Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449

Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587
           D G  G  G+    G+PG +GPKGEPG++        GP G+PG                
Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636
                 PG PG  G  G PG PG +G+PG        L   G  GV G  G  G PG KG
Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566

Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            DG PG PG +GLPGP G + L G  GD G  G+PG  G PGP+GP G    GP+G+ G 
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719
           +G                             PGPPGPPG+       G  G  G+ G  G
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686

Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
            PGP G  G       G PG KG+ G  G  G  G  G++GEPG PGK GL G KG+
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743



 Score =  390 bits (1001), Expect = e-108
 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%)

Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299
           +KG  G+PGPPG  G PG     E+G  G+PG   +G+ G+ G  G PG +G KG RG  
Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348
              G+ GIKG KG  GP G +GP         +G +G  GPPG  G +G QG  G PG P
Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399
           G  GS  PG  G  G  G+KG +G+ GRP     G PG  G  G PG PG  GP G PG+
Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448
               +G PG+ G PG  G  G  G  GP+G  GL       I G  G  G  G  G  GI
Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502
           P  G QG  G++G  G PG  G P   G PG++G+ G  G  G    P G VG+ G  G 
Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553
           +G+PG  GL G PG PG  G  G KGE  L G +G +GPPG     G PGP G       
Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
           G +G  G QG +G+PG  GP GE G  G   +  T +PGPPGP G  G PG  G  G PG
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660
               G  G  G  GP G PG+ G G+PG PGP+G  G PG  G  G              
Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735

Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719
           G  GAKGEP V  P GP  P   G +G  G+ G+ GLPG PG PG  G++G+ G +G  G
Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795

Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753
            PGP G  G                GL G KG+ G RG  G KGD            GE 
Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 754 GEPGSPGKQGLQGPKGDLG 772
           G PG PG QG  GP G  G
Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874



 Score =  294 bits (752), Expect = 4e-79
 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%)

Query: 243  EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297
            +KG+PG      PGPPG  G+PG+ G+ G KG  G  Q G  G  GP G  G  G  G  
Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 298  GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354
            G  GKPG  GD   KG  G  GP G RG  G+ G PG PGP G +G++G  G PGP G  
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 355  GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402
            G  G+           G QG KG+RG  G PG PG  G +G+ G  GP G EG PG  GL
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229

Query: 403  PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452
            PG          G PG +G  G+ GP GP G   + IKG+KG +G  GP+GP G  G +G
Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289

Query: 453  SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507
              G  G  G  G PGP+G  G QG PG KGE G    +G  GP GP+G  G  G +G+PG
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 508  SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560
            ++      G PG PG PGE G  G+ G  G PG  GP GP GK G+ G  G  G  G KG
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588
            N+G +G PGP G  G PG+ G  G  G+
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437



 Score =  214 bits (544), Expect = 5e-55
 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%)

Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560
           G KGE G  G PG PG PG+ G  G +G   LPG +GP     KG PG  G  G KG +G
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94

Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620
             G  G  G  G  G PG  GP+G+ G  +PG  G KG++G PG+PG  G PG+      
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147

Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670
           G  G +G  GAP          KGD G PG PGP+GLPGPPG  G  G  G  G  G PG
Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718
             GP GP G  G    G KG+ G KGL GPPGPPG               +G KG++G  
Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267

Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           G PGP G  G  LPG+    E G  GD G +G  G+ G PG PG +G++G +G  GL  E
Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 777 EIIK 780
           + IK
Sbjct: 326 DGIK 329



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296
            KG+ G+PG  G+ G PG  G +GP   +G+PG  +     G  G  G  G PG +G+   
Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
                      G  G PG  GP GPRG  G  G PG PGP G +GNKG  G PGP GS G 
Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425

Query: 357  PGIGQQGIKGERGQEGRP 374
            P     G+KG+RG  G P
Sbjct: 1426 P-----GLKGKRGDSGSP 1438



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%)

Query: 245  GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            G  G  GPPG  G+PG      + G  GP G PG  + G  GE GP G PG  G  G RG
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
               KPG  G  G+PGP G KG +G +G  GP G  G  G +G +G+ G P  + + G
Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query: 247  PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306
            PG PGPPGT G PG++GE GP G PGN   G  G RG  G  G  G  G  GE G  G K
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 307  GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338
            G+ G  G  G  G +G +G +G P     +GF
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788
           G  G+KGE G  G  G  G KG  G  G PG QG +G  G  GLT  + ++ I+ + G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814
                 G      P  LV V   S S G + F
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score =  431 bits (1109), Expect = e-120
 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%)

Query: 244  KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295
            +GDPG PGPPG  G PG  I+G RG +G PG      Q+G  G+ GP G PG  G    G
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
              GE G PGI G +G  GP G +G  G  GI GPPG+ G  G  G  G  GPPGP G+PG
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 356  APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389
             PG  G  GI G +GQ G PGA         PGP  +                G PG+ G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 390  PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435
             RG  G+PG +GL G     G PGP+G+ GS G  G  GL+G+            KG++G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 436  DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             +G  G  G  G+PGI G QG++G  G      PGP GP G  GLPG  G+ G+MG  GP
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543
             G +G  G +G  G PGS GLPG+PG  G+ G  G KG  G PG RGP G PG       
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 544  ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569
                              KG+       PGP+G+ G +G+KG++G  G PG         
Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210

Query: 570  ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620
               P GP G  G  GP G+PG  IPG  G   P G RG PG PG  G PG   + I+G K
Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270

Query: 621  GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675
            G  G  GP G PG  GD  P    G PG  GLPGP G  G +G  G  G KG PG  G  
Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330

Query: 676  GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728
            GP GP  +G +GP G  G  G      LPG PGPPG  G  G++GE GP G PG  G  G
Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388

Query: 729  -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              G PG+ G+ G  G  G+KG+KG  GEPG  G  GL G KG  G
Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433



 Score =  422 bits (1084), Expect = e-117
 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            EKGD G PGPPG  G  G +G  GP G PG+      G RG  G PG KG KGERG  GK
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 303  --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344
                          PG+ G  G PGP G     KGP G  G+ G  G PG  G  G KGE
Sbjct: 412  DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471

Query: 345  PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391
            PG         PGP G PG PG+ G +GI G +G    +G PG+PG  G+ G PG PG +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 392  GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433
            G  G+ GE+G          +PG+    G PG KG  G  G  G +GL G    L++ GE
Sbjct: 532  GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591

Query: 434  KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484
            KGD GP G         P GP G PG G QGE G+QG  G PG  GP G+   G +GE+ 
Sbjct: 592  KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649

Query: 485  QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528
                  GP GP GP G  G QGP G PGS+G  G PG+PG D           G  G KG
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 529  EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579
            + G PG +G  G PGK G+PG  G  G  G+K        G  G  G PG  G  GE G 
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 580  MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623
            +G  G+PG  +PG P      GP+GD G PG PG +G PG  I GP+G Q          
Sbjct: 770  IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 624  --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675
                    GP+G  G PGL   G+PG  G  G+PG  G MG   +G  G  G PG+ GPP
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885

Query: 676  GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724
            G  G       P  +G  GP G+ G  G  G PG PG     G+ G KGEQG +G PGP 
Sbjct: 886  GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944

Query: 725  GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774
              + H + G KGE G +G  G  G+KG  G PG PG +GL+         GP+GDLG T
Sbjct: 945  SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002



 Score =  411 bits (1057), Expect = e-114
 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%)

Query: 240  CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293
            C  + G+PG PG PG    PG KGE      G  G PG   ++G +GE G  G+PG  G 
Sbjct: 722  CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
             G  G  G  G +GD G PGP G +GP G  I+G  G  G PG  G +G +G  G  GP 
Sbjct: 779  PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404
            G PG PG+ + G  GE G  G PG  G +G        G PG  GP G +GV G  G PG
Sbjct: 839  GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898

Query: 405  E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456
              G PGP G  G+ G  G  G+ G  +KG++G  G  G QG  G PG       IG +GE
Sbjct: 899  AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 457  QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514
             G++G  G PG +G  G  G+PG KG  G  GP GP GP G +G  G  GEPG  G+PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 515  PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556
             G  G  G+ GK+G  G PG  G  G PG                   G PGP GD G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600
            G  G +G+ G PGP G  G  G  G  G PG+  +PG PGP GD               R
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 601  GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648
            G PG+PGF G PG + IRG +G  G  GP G           PG +G+ G  G  G RG 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 649  PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701
            PG PG  G +G +GD G +G  G+ G PGP G      P   G +GP G  G  G PGPP
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 702  GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751
            GPPG    GIKG++G  G PGPKG  G           G PG  G  G RGD G +G  G
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 752  EIGEPGSPGKQGLQGPKGDLG 772
              GE G+PG  G  GP G +G
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337



 Score =  408 bits (1048), Expect = e-113
 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298
            ++G PG PG  G  G PG KGE+G KGNPG ++     G+ GE G  G  G  G+KG RG
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347
              G PG+KG KG PGP GP GPRG  G TG PG+PG +G     GN G PG         
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 348  -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403
             PG  G PG PGI G QG KGE G  EG RPG PGP   G+PG PG  G +G  G+ G P
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091

Query: 404  G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451
            G       EG PG  G  G  G  GP G   L  KG KG +GP G +GP G+PG      
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 452  -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486
                 G QG  GI GP G          PPGP+G  G           G PG  G  G M
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 487  GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545
            G  GPRGP GI G  GP G PG+I       +PG+ G  G  G  G PGA GP GPPG  
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262

Query: 546  QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605
              G KGD   KGS G+ G +G PG  G  G PG +G  G PG  +PGP G  G +G PG+
Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317

Query: 606  PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665
             G KG PG    G  G  GP GP G PG++GD  PG      LPG PGP         G 
Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365

Query: 666  KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724
             GEPG++G PGP GP G +G  GP+G  G+ G PG PGP G      KG +G +G PGP 
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420

Query: 725  GTMGHGLPGQKGEHGERG 742
            G+   GLPG KG+ G+ G
Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436



 Score =  397 bits (1021), Expect = e-110
 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287
           C   KG+ G PG PGT G PGI G  G KG  G   K            G  G  GP G+
Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184

Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333
           PG  G  G  G  G PG  G  G+ GP GP           KG RG++G+TGPPG P   
Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244

Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371
                         G KG +G  GEPGPPGP G P        GAP  G  G++G+ G++
Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302

Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411
           G PG PG  GV G  G PG  G +G+ G++G  G                   EG PGP 
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452
           G +G+ GP GP G  G+                   +KG KG+ G  G +  MG PG  G
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421

Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498
             G  G+ G  GPPGP G        P   GLPG  G  G  G  GP+G  G+       
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558
           + GP G PG  GL G  G+PG  GAAG KG  G PG  G  G P  G PG +GD G KG 
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539

Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613
           KG     +GQ G+PG  G +G+PG  G  G+PGT  + G PGPKG+    G  G +G PG
Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668
               G  G  GP GP G PG    G PG+ G +G+PG PGP G  G        T   G 
Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657

Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724
           PG  GPPG  GP+G  G  G  G  G  GLPGP   PG PG G  G  G +G QGFPG K
Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717

Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755
           G++G              GLPG KGE         G  G  G++G+ GE GE        
Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 756 -PGSPGKQGLQGPKGDLG 772
            PG+PG +GL GP+GD G
Sbjct: 778 LPGTPGNEGLDGPRGDPG 795



 Score =  390 bits (1002), Expect = e-108
 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
           C+  KG+ G+ G PG  G+PG KG  GP+G P     G  G +G  G+PG  G KG RG 
Sbjct: 41  CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95

Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
            G PG  G  G PG  G  GP G+ G+      PG  G +G +G PG PG  G PG PG 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149

Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406
            G +G KG            +G  G PGAPGP G+ G PG PGP GP G PG  G PG  
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439
            P            G KGE+G +G TGP G  G  I               KG+KG +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457
            GP GP G+PG                                          +G  G +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498
           G +G IGPPG +GP            +G PG  G  G  GP GP GP G+         G
Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389

Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551
           ++G  G PG  G  G+ G PG+D     G+ G  G  GLPG+ GP GPPG    + GP G
Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449

Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587
           D G  G  G+    G+PG +GPKGEPG++        GP G+PG                
Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636
                 PG PG  G  G PG PG +G+PG        L   G  GV G  G  G PG KG
Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566

Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            DG PG PG +GLPGP G + L G  GD G  G+PG  G PGP+GP G    GP+G+ G 
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719
           +G                             PGPPGPPG+       G  G  G+ G  G
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686

Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
            PGP G  G       G PG KG+ G  G  G  G  G++GEPG PGK GL G KG+
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743



 Score =  390 bits (1001), Expect = e-108
 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%)

Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299
           +KG  G+PGPPG  G PG     E+G  G+PG   +G+ G+ G  G PG +G KG RG  
Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348
              G+ GIKG KG  GP G +GP         +G +G  GPPG  G +G QG  G PG P
Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399
           G  GS  PG  G  G  G+KG +G+ GRP     G PG  G  G PG PG  GP G PG+
Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448
               +G PG+ G PG  G  G  G  GP+G  GL       I G  G  G  G  G  GI
Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502
           P  G QG  G++G  G PG  G P   G PG++G+ G  G  G    P G VG+ G  G 
Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553
           +G+PG  GL G PG PG  G  G KGE  L G +G +GPPG     G PGP G       
Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
           G +G  G QG +G+PG  GP GE G  G   +  T +PGPPGP G  G PG  G  G PG
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660
               G  G  G  GP G PG+ G G+PG PGP+G  G PG  G  G              
Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735

Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719
           G  GAKGEP V  P GP  P   G +G  G+ G+ GLPG PG PG  G++G+ G +G  G
Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795

Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753
            PGP G  G                GL G KG+ G RG  G KGD            GE 
Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 754 GEPGSPGKQGLQGPKGDLG 772
           G PG PG QG  GP G  G
Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874



 Score =  294 bits (752), Expect = 4e-79
 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%)

Query: 243  EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297
            +KG+PG      PGPPG  G+PG+ G+ G KG  G  Q G  G  GP G  G  G  G  
Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 298  GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354
            G  GKPG  GD   KG  G  GP G RG  G+ G PG PGP G +G++G  G PGP G  
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 355  GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402
            G  G+           G QG KG+RG  G PG PG  G +G+ G  GP G EG PG  GL
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229

Query: 403  PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452
            PG          G PG +G  G+ GP GP G   + IKG+KG +G  GP+GP G  G +G
Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289

Query: 453  SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507
              G  G  G  G PGP+G  G QG PG KGE G    +G  GP GP+G  G  G +G+PG
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 508  SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560
            ++      G PG PG PGE G  G+ G  G PG  GP GP GK G+ G  G  G  G KG
Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409

Query: 561  NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588
            N+G +G PGP G  G PG+ G  G  G+
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437



 Score =  214 bits (544), Expect = 5e-55
 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%)

Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560
           G KGE G  G PG PG PG+ G  G +G   LPG +GP     KG PG  G  G KG +G
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94

Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620
             G  G  G  G  G PG  GP+G+ G  +PG  G KG++G PG+PG  G PG+      
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147

Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670
           G  G +G  GAP          KGD G PG PGP+GLPGPPG  G  G  G  G  G PG
Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718
             GP GP G  G    G KG+ G KGL GPPGPPG               +G KG++G  
Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267

Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           G PGP G  G  LPG+    E G  GD G +G  G+ G PG PG +G++G +G  GL  E
Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 777 EIIK 780
           + IK
Sbjct: 326 DGIK 329



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296
            KG+ G+PG  G+ G PG  G +GP   +G+PG  +     G  G  G  G PG +G+   
Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
                      G  G PG  GP GPRG  G  G PG PGP G +GNKG  G PGP GS G 
Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425

Query: 357  PGIGQQGIKGERGQEGRP 374
            P     G+KG+RG  G P
Sbjct: 1426 P-----GLKGKRGDSGSP 1438



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%)

Query: 245  GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            G  G  GPPG  G+PG      + G  GP G PG  + G  GE GP G PG  G  G RG
Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
               KPG  G  G+PGP G KG +G +G  GP G  G  G +G +G+ G P  + + G
Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query: 247  PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306
            PG PGPPGT G PG++GE GP G PGN   G  G RG  G  G  G  G  GE G  G K
Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 307  GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338
            G+ G  G  G  G +G +G +G P     +GF
Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788
           G  G+KGE G  G  G  G KG  G  G PG QG +G  G  GLT  + ++ I+ + G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814
                 G      P  LV V   S S G + F
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  431 bits (1107), Expect = e-120
 Identities = 287/640 (44%), Positives = 330/640 (51%), Gaps = 126/640 (19%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG----------------PG-- 285
            +G PG  GPPG  G PGIKGE+G  G PG    G  G++G                PG  
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866

Query: 286  ---GIPGYKGDKGERGECG---KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQ 339
               GIPG+ G KGE G  G   +PG  G  G+PG  G KG  G  G +GP GDPG KG +
Sbjct: 867  GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDK 926

Query: 340  GNKGEPGPPGPY------------GSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEP 385
            G+ G PG PG              G  G  G IG  G KG RG  G PG PG  G  G+P
Sbjct: 927  GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQP 986

Query: 386  GQPGPRGPEGV---PGERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGL-SIKGEK 434
            GQPGP+G  G+   PG  GLPG        G PG  GEKG  G  GPQG  GL   KG K
Sbjct: 987  GQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK 1046

Query: 435  GDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP 494
            G+ G  GP G +GIPG+  +GE+G QG  G PG         PG KGE G +G  G  G 
Sbjct: 1047 GEKGQAGPPG-IGIPGL--RGEKGDQGIAGFPGS--------PGEKGEKGSIGIPGMPGS 1095

Query: 495  VGIGVQGPKGEPGSIGLPGQPGVPGE---------DGAAGKKGEAGLPGARGPEGPPG-K 544
             G+     KG PGS+G PG PG+PGE         DG  G KGEAGLPG  GP GP G K
Sbjct: 1096 PGL-----KGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 545  GQPGPKGDEGKKGSKGNQGQ--RGLPGPEGPKGEPGIMGPFGMPGTS-IPGPPGPKGDRG 601
            G+PG  G  G  G KG  G   RG PG  G KG+ G  G  G PG +  PG PG KG++G
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210

Query: 602  GPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGL---------------KGD-GY 639
              G PG +G+PGL      +  GPKG +GP+G  G PGL               KGD G 
Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270

Query: 640  PGVPGPRGLPGPPGPMGLRGV-------GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGD 691
            PG PG  G+PGP G  G +G+       G TG+KG+ G  G PG  GP+G+ G QG KGD
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 692  TGQ------KGLPGPPGPPG-----YGSQGIKGEQGP------QGFPGPKGTMG-HGLPG 733
             G       KGLPGPPGPPG      G  G+ G +GP      QG PGPKG  G  GL G
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390

Query: 734  QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
              G  G  G  G  G KGE+G  G  G +G  GP G  GL
Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430



 Score =  425 bits (1092), Expect = e-118
 Identities = 296/727 (40%), Positives = 337/727 (46%), Gaps = 199/727 (27%)

Query: 243 EKGDPGDPGPPG--------------THGNPGIKGERGPKGNPGNAQKGEAGERGPGGIP 288
           +KGD G  GPPG              T G  G KGE G +G PG  +KGE G+ GP G P
Sbjct: 230 DKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKP 289

Query: 289 GYKGDKGERGECGKPGI------------KGDKGSPGPYGP------------KGPRGIQ 324
           G  GDKGE+G  G PG             +G+KG  GP GP            KG RG  
Sbjct: 290 GKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYP 349

Query: 325 GITGPPGDPGPKGFQGNKGEPGPPG--PYGSPGAPGI-GQQGIKGER--------GQEGR 373
           G  GP G+PGPKGF G  G+PGPPG    G  GAPG  G++G KG+R        G  GR
Sbjct: 350 GTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409

Query: 374 PGAPGPIG-VGEPGQP-------------------------------------------- 388
            G PGP G  G PGQP                                            
Sbjct: 410 DGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLI 469

Query: 389 -------GPRGPEGVPGERGLPGE-------GFPGPKGEKGSEGPTGPQGLQG------- 427
                  GP GP+G PGE G PG+       G PG  G  G  GP G  GL G       
Sbjct: 470 CDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE 529

Query: 428 -------LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ-GLPG 478
                  L +KG+KGD G  G  G  G  G  G  G  G+ GP G PG  G  G+ G PG
Sbjct: 530 PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPG 589

Query: 479 SKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE-AGLPGARG 537
             G  G  G TGP GP G G  GP G+ G  G PG PG PG  G  G+ G+   LPG  G
Sbjct: 590 GVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPG 649

Query: 538 PEGPPGK-GQPGPKGDE---------GKKGSKGNQGQRGL--PGPEGPKGEPGIMGPFGM 585
            EG PG  G PGP+GD          G  G KG  GQ G+  PGP GPKG  G+ G  G 
Sbjct: 650 AEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP 709

Query: 586 PGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPG 644
           PGT  PG PG  G  G PG+ G KGEPG+ + G KG+ G  G  G PG KG  G PGVPG
Sbjct: 710 PGT--PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPG 767

Query: 645 PRGLPGPPGPMGLR------------------GVGDTGAKGEPGVRGPPGPSGPRGVGTQ 686
             G  GPPG  G+R                  G+G  GA+G PG +GPPG SGP G+  +
Sbjct: 768 EHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGE 827

Query: 687 ------------GPKGD---------TGQKGLPGPPGPPGY----GSQGIKGEQGPQGFP 721
                       GPKGD         TGQ GLPG PG  G     G  G KGE G  G P
Sbjct: 828 KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887

Query: 722 GPKGTMG----HGLPGQKGEH------GERGDVGKKGDKGEIGEPGSPGKQ------GLQ 765
           G  G+ G     GLPG+KG+H      G RGD G KGDKG++G PG PG         ++
Sbjct: 888 GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMK 947

Query: 766 GPKGDLG 772
           G KGD G
Sbjct: 948 GQKGDQG 954



 Score =  425 bits (1092), Expect = e-118
 Identities = 274/615 (44%), Positives = 319/615 (51%), Gaps = 95/615 (15%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK-----GDKGERG- 298
            G PG PGP G+ G+ G+KGERGP G  G    G  G+ GP G PGY      GDKG+ G 
Sbjct: 565  GHPGLPGPKGSPGSVGLKGERGPPGGVGFP--GSRGDTGPPGPPGYGPAGPIGDKGQAGF 622

Query: 299  --ECGKPGIKGDKGSPGPYGP-KGPRGIQGITGPPGDPGP---KGFQGNKGEPGPPGPYG 352
                G PG+ G KG PG   P  GP G +G+ G PG PGP   +GF G  G PG PG  G
Sbjct: 623  PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKG 682

Query: 353  SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEG-----VPGER 400
            + G PGIG  G  G +G +G PG  GP G        G PG PG +G +G     +PG +
Sbjct: 683  AVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLK 742

Query: 401  GLPG-EGFPGPKGEKGS---------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450
            GLPG  G PG  GEKGS          G  GP GLQG  I+GE G  G  G  G  G+PG
Sbjct: 743  GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQG--IRGEPGPPGLPGSVGSPGVPG 800

Query: 451  IGSQGEQGIQGPIGPPGPQGPAG------------------------QGLPGSKGEVGQM 486
            IG  G +G  G  GPPG  GP G                        QGLPG  G+ G  
Sbjct: 801  IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLP 860

Query: 487  GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPP 542
            G  G +G  GI G  G KGE G +G PGQPG PG  GA G   +KG+ G PG+ GP G P
Sbjct: 861  GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDP 920

Query: 543  G-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT----SIPGPPGPK 597
            G KG  G  G  GK GS        + G +G +GE G +GP G  G+      PG PG  
Sbjct: 921  GLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKD 980

Query: 598  GDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMG 656
            G  G PG PG KG+PG+S   G  G+ GP+G VG  GL     PG PG +G+PG PGP G
Sbjct: 981  GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL-----PGTPGEKGVPGIPGPQG 1035

Query: 657  LRGV-GDTGAKGEPGVRGPPG--------PSGPRGV----GTQGPKGDTGQKGLPGPPGP 703
              G+ GD GAKGE G  GPPG          G +G+    G+ G KG+ G  G+PG PG 
Sbjct: 1036 SPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS 1095

Query: 704  PGY-GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758
            PG  GS G  G  G  G PG KG  G     G+PG KGE G  G  G  G  G+ GEPGS
Sbjct: 1096 PGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS 1155

Query: 759  PGKQGLQGPKGDLGL 773
             G  G  G KG+ GL
Sbjct: 1156 DGIPGSAGEKGEPGL 1170



 Score =  422 bits (1086), Expect = e-118
 Identities = 269/633 (42%), Positives = 321/633 (50%), Gaps = 104/633 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKG------- 295
            + G PG PG PG +G PG  G +G KG PG    G  G  G  GIPG  G+KG       
Sbjct: 706  DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGV 765

Query: 296  --ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITG--PPGDPGPKGFQGNKGEPGPPGPY 351
              E G  G PG++G +G PGP G  G  G  G+ G  PPG  GP G QG  G  GPPG  
Sbjct: 766  PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIK 825

Query: 352  GSPGAPGI------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG 398
            G  G PG             G QG+ G  GQ G PG PG  G  G PG PG +G  GV G
Sbjct: 826  GEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMG 885

Query: 399  ERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI 451
              G PG        G PG KG+ G  G +GP+G  GL  KG+KGD+G  G  G M    +
Sbjct: 886  TPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL--KGDKGDVGLPGKPGSMDKVDM 943

Query: 452  GS-------QGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGI------ 497
            GS       QGE+G  GPIG  G +G P   G+PG  G+ GQ G  GP+G  GI      
Sbjct: 944  GSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGA 1003

Query: 498  -GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK 556
             G+ GPKG  G +GLPG PG  G  G  G +G  GLPG +G +G  G+  P   G  G +
Sbjct: 1004 PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-------------SIPGPPGPKGDRGGP 603
            G KG+QG  G PG  G KGE G +G  GMPG+               PG PG KGD+G P
Sbjct: 1064 GEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLP 1123

Query: 604  G---IPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRG 647
            G   IPG KGE GL                G  G+ G  G  G PGL G G+PG PG +G
Sbjct: 1124 GLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG 1183

Query: 648  LPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV------GTQGPKGDTGQKG- 696
              G  G +G  G+    G  G+KGE G  GPPGP G  G+       T+GPKGD G +G 
Sbjct: 1184 DKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ 1243

Query: 697  -----LPGPPGPPGY-GSQGIKGEQGPQGFPG------PKGTMGH----GLPGQKGEHGE 740
                 LPGP GPPG  G  G+KG++G  G+PG      PKG  G     G+ G  G  G 
Sbjct: 1244 PGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGS 1303

Query: 741  RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
            +GD+G  G  G  G  G PG QG++G +GD G+
Sbjct: 1304 KGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGV 1336



 Score =  420 bits (1080), Expect = e-117
 Identities = 278/679 (40%), Positives = 324/679 (47%), Gaps = 148/679 (21%)

Query: 234 KCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGD 293
           KC+    + +KG+ G PG  G  G PG++G  GP+G PG  QKG+ GE G  G  G +G 
Sbjct: 38  KCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPG--QKGDTGEPGLPGTKGTRGP 95

Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353
            G  G  G PG+ G  G  GP GP G  G  G  G  G  GP G  G  G PGPPG  G 
Sbjct: 96  PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGM 155

Query: 354 PGAPG-----IGQQGIKGERGQEGRPGAPGPIG-------VGEP---GQPGPRGPEGVPG 398
            G PG     +    +KGERG  G PG PGP G       VG P   G PGP GP G PG
Sbjct: 156 KGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215

Query: 399 ERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI------GPVGPQGPMGIPGIG 452
           E+G  G  F GPKG+KG +G +GP G+ G +   EKGD       G  G  G  G+PG+G
Sbjct: 216 EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVG 275

Query: 453 SQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPVGI-- 497
            +GE G  GP G PG  G  G+             GL G +G  G+ G  GP GP GI  
Sbjct: 276 EKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVI 335

Query: 498 --------------GVQGPKGEPGSIGLPGQPG--------VPGEDGAAGKKGEA----- 530
                         G  GP+GEPG  G PG PG        VPG+ GA G  GE      
Sbjct: 336 GTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGD 395

Query: 531 ---------------GLPGARGPEGPPGKG---------QPGPKGDE------------- 553
                          GLPG  G  GPPG+          QPGP GD+             
Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 455

Query: 554 --GKKGSKGN-------QGQRGLPGPEGPKGE------PGIMGPFGMPG-TSIPGPPGPK 597
             G+KG KG         G RG PGP+GP GE      PG  G  G+PG   + G PGP+
Sbjct: 456 EIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQ 515

Query: 598 GDRGGPGIPGFKGEPG-----LSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGL 648
           G  G  G PG KGEPG     L ++G KG  G  G  G  G  G    DG+PG+PGP+G 
Sbjct: 516 GTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGS 575

Query: 649 PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-- 706
           PG  G  G R  G  G  G PG RG  GP GP G G  GP GD GQ G PG PG PG   
Sbjct: 576 PGSVGLKGER--GPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPG 633

Query: 707 ------------GSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEI 753
                       G  G +G  G  GFPGP+G  G  G PG+ G  GE+G VG+ G    I
Sbjct: 634 PKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG----I 689

Query: 754 GEPGSPGKQGLQGPKGDLG 772
           G PG PG +G+ G  GD+G
Sbjct: 690 GFPGPPGPKGVDGLPGDMG 708



 Score =  418 bits (1074), Expect = e-116
 Identities = 272/645 (42%), Positives = 314/645 (48%), Gaps = 129/645 (20%)

Query: 245  GDPGDPGP------PGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            G PG PGP      PGT G PG+ GE+G  G PG    G  G  GP G+ G  GD G  G
Sbjct: 655  GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI---GFPGPPGPKGVDGLPGDMGPPG 711

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGI-----QGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353
              G+PG  G  G+PG  G KG  G+     +G+ G PG PG  G +G+ G PG PG +G+
Sbjct: 712  TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGA 771

Query: 354  PGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGE 413
             G PG+  QGI+GE G  G PG+ G  GV   G PG RGP G  G  GL G   PG KGE
Sbjct: 772  IGPPGL--QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGP--PGIKGE 827

Query: 414  KG--------SEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463
            KG          GP G +G QGL  I G+ G  G  G QG  GIPG  GS+GE G+ G  
Sbjct: 828  KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887

Query: 464  GPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI------------------------- 497
            G PG  GP G  GLPG KG+ G  G +GPRG  G+                         
Sbjct: 888  GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMK 947

Query: 498  ---------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQP 547
                     G  GP GE GS G PG PGVPG+DG AG+ G+ G  G  G  G PG  G P
Sbjct: 948  GQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP 1007

Query: 548  GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP--------------FGMPG------ 587
            GPKG  G  G  G  G++G+PG  GP+G PG+ G                G+PG      
Sbjct: 1008 GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKG 1067

Query: 588  ----TSIPGPPGPKGDRGGPGIPGFKGEPGLS-------IRGPKGVQGPRGPVGAPGLKG 636
                   PG PG KG++G  GIPG  G PGL          G  G+ G +G  G PGL  
Sbjct: 1068 DQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGL-- 1125

Query: 637  DGYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRGVGTQ 686
            DG PGV G  GLPG PGP G  G           G  G KGEPG+ G   P  P   G +
Sbjct: 1126 DGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDK 1185

Query: 687  GPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVG 745
            G KG+ G  GL G PG PG  G QG  G  GPQG PG  G+ GH   G KG+ G +G  G
Sbjct: 1186 GSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG 1245

Query: 746  K------------------KGDKGEIGEPGSPGKQGLQGPKGDLG 772
                               KGDKG    PG PG  G+ GPKGD G
Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGN---PGWPGAPGVPGPKGDPG 1287



 Score =  408 bits (1048), Expect = e-113
 Identities = 261/585 (44%), Positives = 312/585 (53%), Gaps = 74/585 (12%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            KGD GDPG PG  G  G  G  G  G+PG       G +G  G  G KG++G  G  G P
Sbjct: 540  KGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP-----GPKGSPGSVGLKGERGPPGGVGFP 594

Query: 304  GIKGDKGSPGP--YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG-------PPGPYGSP 354
            G +GD G PGP  YGP GP G +G  G PG PG  G  G KGEPG       PPG  G P
Sbjct: 595  GSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP 654

Query: 355  GAPGI-GQQGIKGERGQEGRPGAPGPIG------VGEPGQPGPRGPEGVPGERGLPGE-G 406
            G+PG  G QG +G  G  GRPG PG  G      +G PG PGP+G +G+PG+ G PG  G
Sbjct: 655  GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPG 714

Query: 407  FPGPKGEKGSEGPTGPQGLQGLSIKGEKG------DIGPVGPQGPMGIPG-------IGS 453
             PG  G  G+ G  G +G  G+ + G KG        G  G +G +G+PG       IG 
Sbjct: 715  RPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP 774

Query: 454  QGEQGIQGPIGPPGPQGPAGQ------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPG 507
             G QGI+G  GPPG  G  G       G PG++G  G  GP G  GP GI  +G KG PG
Sbjct: 775  PGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGI--KGEKGFPG 832

Query: 508  SIGL--PGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR 565
              GL  PG  G  G  G  G  G++GLPG  G +G PG   PG  G +G+ G  G  GQ 
Sbjct: 833  FPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGI--PGFPGSKGEMGVMGTPGQP 890

Query: 566  GLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGL----SIRGPK 620
            G PGP G  G PG  G  G PG+S P G PG KGD+G  G+PG  G        S++G K
Sbjct: 891  GSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950

Query: 621  GVQGPRG---PVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676
            G QG +G   P+G  G +GD G PGVPG  G  G PG  G +G  D G  G PG  G PG
Sbjct: 951  GDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG--DPGISGTPGAPGLPG 1008

Query: 677  PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736
            P G   VG  G  G  G+KG+PG PGP G  S G+ G++G +G  G  G  G G+PG +G
Sbjct: 1009 PKG--SVGGMGLPGTPGEKGVPGIPGPQG--SPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064

Query: 737  EHGERGD---------VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            E   +GD          G+KG+KG IG PG PG  GL+G  G +G
Sbjct: 1065 E---KGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106



 Score =  398 bits (1023), Expect = e-110
 Identities = 270/604 (44%), Positives = 299/604 (49%), Gaps = 85/604 (14%)

Query: 239  ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA--------QKGEAGERGPGGIPGY 290
            I EC+ G PGD GPPG  G PG  GE G KG  G +         +G  G +GP G  G+
Sbjct: 431  IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGF 490

Query: 291  KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG-------------DPGPKG 337
             G  G +G+ G PG  G  G PGP G  G  G  G  G PG             DPG  G
Sbjct: 491  PGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPG 550

Query: 338  FQGNKGEPGPPGPYGSPGAPGI----GQQGIKGERGQEGRPGAPGPIG-VGEPGQPG--P 390
              G  G  G PG  G PG PG     G  G+KGERG  G  G PG  G  G PG PG  P
Sbjct: 551  QPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGP 610

Query: 391  RGPEGVPGERGLPG----EGFPGPKGEKGSEGPT-GPQGLQGLSIKGEKGDIGPVGPQGP 445
             GP G  G+ G PG     G PGPKGE G   P  GP G +GL      G  G  GPQG 
Sbjct: 611  AGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP-----GSPGFPGPQGD 665

Query: 446  MGIPGI----GSQGEQGIQGP--IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG-PVGI 497
             G PG     G  GE+G  G   IG PGP GP G  GLPG  G  G  G  G  G P   
Sbjct: 666  RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNP 725

Query: 498  GVQGPKGEPGS-----IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPG 548
            GVQG KGEPG       GLPG PG+PG  G  G  G  G+PG  G  GPPG    +G+PG
Sbjct: 726  GVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPG 785

Query: 549  PKGDEGKKGSKG-----NQGQRGLPGPEGP---KGEPGIMGPFGMPGTSIPGPPGPKGDR 600
            P G  G  GS G       G RG PG +GP    G PGI G  G PG      PGPKGD+
Sbjct: 786  PPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDK 845

Query: 601  GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660
            G  G+PG  G+ GL   G  G QG  G  G PG KG+   GV G  G PG PGP     V
Sbjct: 846  GAQGLPGITGQSGLP--GLPGQQGAPGIPGFPGSKGE--MGVMGTPGQPGSPGP-----V 896

Query: 661  GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY----------GSQG 710
            G  G  GE G  G PG SGPRG    G KGD G  GLPG PG              G QG
Sbjct: 897  GAPGLPGEKGDHGFPGSSGPRG--DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQG 954

Query: 711  IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769
             KG+ GP G  G +G  G  G+PG+ G+ G+ G  G KGD G  G PG+PG  G +G  G
Sbjct: 955  EKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVG 1014

Query: 770  DLGL 773
             +GL
Sbjct: 1015 GMGL 1018



 Score =  378 bits (971), Expect = e-104
 Identities = 252/605 (41%), Positives = 297/605 (49%), Gaps = 116/605 (19%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGPGGIPG 289
            EKGD G PG  G  G+PG+KG++G  G PG               QKG+ GE+G  G  G
Sbjct: 904  EKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIG 963

Query: 290  YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349
             KG +G+ G  G PG  G  G PG  GPKG  GI G  G PG PGPKG  G  G PG PG
Sbjct: 964  EKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG 1023

Query: 350  PYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE--- 405
              G PG PG  G  G+ G++G +G  G  GP G+G PG  G +G +G+ G  G PGE   
Sbjct: 1024 EKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE 1083

Query: 406  -------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQ 457
                   G PG  G KGS G  G  G  GL   GEKGD G  G  G   IPG+ G  G  
Sbjct: 1084 KGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP--GEKGDKGLPGLDG---IPGVKGEAGLP 1138

Query: 458  GIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG---PRGPVGIGVQGPKGEPGSIGLPG 513
            G  GP GP G +G P   G+PGS GE G+ G  G   P  P   G +G KGE G  GL G
Sbjct: 1139 GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAG 1198

Query: 514  QPGVPGEDGAAG------KKGEAGLPGA-----------RGPEGPPG-------KGQPGP 549
             PG+PG  G  G       +G+ GLPG+           RGP+G PG        G PG 
Sbjct: 1199 SPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGL 1258

Query: 550  KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFK 609
             G +G KG KGN G  G PG  GPKG+PG  G  G+ G+  PG  G KGD G PG+PGF+
Sbjct: 1259 PGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS--PGITGSKGDMGPPGVPGFQ 1316

Query: 610  GEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPR-------GLPGPPGPMGLRGV- 660
            G  GL   G +G++G +G  G PG KG  G PG PGP        GLPGP GP GL+G+ 
Sbjct: 1317 GPKGLP--GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQ 1374

Query: 661  ------------------------GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKG 696
                                    G  GA G+ G  GP GP+GPRG    GP G  G  G
Sbjct: 1375 GLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGF--PGPPGPDGLPG 1432

Query: 697  LPGPPGPPGYG--------SQGIKGEQGPQGFPGPKGTMGHG-----LPGQKGEHGERGD 743
              GPPG P           SQ I   Q P G       + HG     + G +  HG+  D
Sbjct: 1433 SMGPPGTPSVDHGFLVTRHSQTIDDPQCPSG----TKILYHGYSLLYVQGNERAHGQ--D 1486

Query: 744  VGKKG 748
            +G  G
Sbjct: 1487 LGTAG 1491



 Score =  298 bits (762), Expect = 3e-80
 Identities = 206/496 (41%), Positives = 241/496 (48%), Gaps = 100/496 (20%)

Query: 370 QEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGL 425
           +  R  A G       G+    G +G  GERGLPG     GFPG +G +G +GP G +G 
Sbjct: 21  EHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGD 80

Query: 426 QG-LSIKGEKGDIGPV------------------GPQGPMGIPGIGSQGEQGIQGPIGPP 466
            G   + G KG  GP                   GP GP GIP  G  G +G +GP+GPP
Sbjct: 81  TGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIP--GCNGTKGERGPLGPP 138

Query: 467 GPQGPAGQ----GLPGSKGEVGQM----------------GPTGPRGPVGI-GVQGPKGE 505
           G  G AG     GLPG KG+ G++                G  G  GP G+ G+QGP G 
Sbjct: 139 GLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGP 198

Query: 506 PGSIGLPGQPGVPGEDGAAGK--------KGEAGLPGARGPEGPPGKGQPGPKGD---EG 554
           PG  G PG PG PG  G  G+        KG+ G  G  GP G PG+ Q   KGD   +G
Sbjct: 199 PGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKG 258

Query: 555 KKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL 614
           +KG KG  G +G+PG  G KGEPG  GP G PG       G KG++G PG PG  G PGL
Sbjct: 259 EKGQKGEPGFQGMPG-VGEKGEPGKPGPRGKPGKD-----GDKGEKGSPGFPGEPGYPGL 312

Query: 615 SIR-GPKGVQGPRGPVGAPGL---------KGD-GYPGVPGPRGLPGP---------PGP 654
             R GP+G +G  GP G PG+         KG+ GYPG PGPRG PGP         PGP
Sbjct: 313 IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372

Query: 655 MGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYG------- 707
            GL   G  GA G PG RG  G  G  G    GP G  G  G PG PGPPG         
Sbjct: 373 PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432

Query: 708 --SQGIKGEQGPQGFPGPKGTMGH-GLPGQKGE-------HGERGDVGKKGDKGEIGEPG 757
               G  G+QGP G PG  G +G  G  GQKGE        G RG  G +G  GEIG PG
Sbjct: 433 ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492

Query: 758 SPGKQGLQGPKGDLGL 773
            PG +G +G  G  G+
Sbjct: 493 QPGAKGDRGLPGRDGV 508



 Score =  161 bits (407), Expect = 4e-39
 Identities = 108/249 (43%), Positives = 122/249 (48%), Gaps = 39/249 (15%)

Query: 241  ECEKGDPGD---------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK 291
            E  KGD G          PGP G  G PGI G +G KGNPG    G  G  GP G PG++
Sbjct: 1232 EGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG--WPGAPGVPGPKGDPGFQ 1289

Query: 292  GDKGERGECGKPGIKGDKGSPGP---YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348
            G  G  G  G  G KGD G PG     GPKG  G+QGI G  GD G  G +G  G PGPP
Sbjct: 1290 GMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPP 1349

Query: 349  GPY----GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG 404
            GPY    G PG P     G +G  G +G  G PGP      GQ G  G  G+PG  G+PG
Sbjct: 1350 GPYDIIKGEPGLP-----GPEGPPGLKGLQGLPGP-----KGQQGVTGLVGIPGPPGIPG 1399

Query: 405  -EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIG-----SQGEQG 458
             +G PG KGE G  GPTGP+G       G  G  G  G  GP G P +      ++  Q 
Sbjct: 1400 FDGAPGQKGEMGPAGPTGPRG-----FPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQT 1454

Query: 459  IQGPIGPPG 467
            I  P  P G
Sbjct: 1455 IDDPQCPSG 1463



 Score =  135 bits (341), Expect = 2e-31
 Identities = 90/200 (45%), Positives = 104/200 (52%), Gaps = 36/200 (18%)

Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPG 650
           G  G KG+RG PG+ G  G PG+        QGP GP G PG KGD G PG+PG +G  G
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGM--------QGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94

Query: 651 PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPG---PPGPPGY 706
           PPG  G  G  + G  G PG  GPPGP G  G  GT+G +G  G  GLPG    PGPPG 
Sbjct: 95  PPGASGYPG--NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGL 152

Query: 707 -GSQGIKGE----------QGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIG 754
            G +G  GE          +G +GFPG  GT G  GLPG +G           G  G  G
Sbjct: 153 PGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGP---------VGPPGFTG 203

Query: 755 EPGSPGKQGLQGPKGDLGLT 774
            PG PG  G  G KG +GL+
Sbjct: 204 PPGPPGPPGPPGEKGQMGLS 223



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 42/95 (44%), Positives = 51/95 (53%), Gaps = 8/95 (8%)

Query: 239  ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298
            I + E G PG  GPPG  G  G+ G +G +G       G  G  GP GIPG+ G  G++G
Sbjct: 1354 IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQG-----VTGLVGIPGPPGIPGFDGAPGQKG 1408

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP 333
            E G  G  G +G P   GP GP G+ G  GPPG P
Sbjct: 1409 EMGPAGPTGPRGFP---GPPGPDGLPGSMGPPGTP 1440



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 5/93 (5%)

Query: 710 GIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765
           G+KG++G +G PG +G +G     G  G +G  G++GD G+ G  G  G  G PG  G  
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 766 GPKGDLGLTKEEIIKLITEICGC-GPKCKETPL 797
           G  G  G+  ++       I GC G K +  PL
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPL 135


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  430 bits (1105), Expect = e-120
 Identities = 270/652 (41%), Positives = 328/652 (50%), Gaps = 130/652 (19%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G PG PG PG  G PG+KG +G  G PG   +G  GE G  G+PG +G  G RG  G  G
Sbjct: 759  GKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTG 818

Query: 305  IKGDKGSPGPYGPKGPRGIQG--ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362
             KG +GSPG  G  GP G  G  ++GPPG  G +G  G +G PG  GP G  G PG    
Sbjct: 819  EKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSC 878

Query: 363  GIKGERGQEGRPGAPG--------PIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGP--- 410
              +G+    G PGAPG        P   G PG PGP GP GVPG +G+PG  G PG    
Sbjct: 879  PSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGL 938

Query: 411  ----------------------------------KGEKGSEGPTGPQGL----------- 425
                                              KGEKG +G  G  GL           
Sbjct: 939  TAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLE 998

Query: 426  -------QGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG---- 473
                   +G + +G+ G +G  G  GP G+PG  G +G  G++G  GPPGP GP G    
Sbjct: 999  RPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGA 1058

Query: 474  ---QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGE---DGAAGKK 527
                GLPG +GE G  G TG +G  G    G  G PG+ G PG PG+ GE    G+AG+K
Sbjct: 1059 VGSPGLPGLQGERGLTGLTGDKGEPG--PPGQPGYPGATGPPGLPGIKGERGYTGSAGEK 1116

Query: 528  GEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGP---------- 573
            GE G PG+ G  GPPG    +G+ GP+G+ G+KG +G QGQ G PGP GP          
Sbjct: 1117 GEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSP 1176

Query: 574  --------KGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQG 624
                    KG  GI GP G+PG+  PGPPGP G +G  G+ G  G+ G   +RG  G  G
Sbjct: 1177 GPPGPQAEKGSEGIRGPSGLPGS--PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAG 1234

Query: 625  PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP--------- 674
            P G +G PG KG  G+PG+PGP+G  G PGP G    G  GA+GEPG  GP         
Sbjct: 1235 PPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPG--STGRPGAEGEPGAMGPQGRPGPPGH 1292

Query: 675  ---------PGPSGPRGVGTQGPKGDTGQKGL---PGPPGPPGY-GSQGIKGEQGPQGFP 721
                     PGP+G   VG +G +G TG++GL   PG PGPPG+ G  G  G  G  G  
Sbjct: 1293 VGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKE 1352

Query: 722  GPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            GP G  G +G PG KG+ G  G  G+ G+KG  G PG PGK G  GP G  G
Sbjct: 1353 GPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPG 1404



 Score =  401 bits (1031), Expect = e-111
 Identities = 262/616 (42%), Positives = 300/616 (48%), Gaps = 112/616 (18%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE------R 297
            +GDPG  G PG  G PG+ G+RG +G PG   +G  G  GP G PG+ G  G       +
Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPG--MRGSPGPPGPIGPPGFPGAVGSPGLPGLQ 1068

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQG------NKGEPGPPGPY 351
            GE G  G+ GDKG PGP    G  G  G TGPPG PG KG +G       KGEPGPPG  
Sbjct: 1069 GERGLTGLTGDKGEPGP---PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1125

Query: 352  GSPGAPGI----------GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGP---R 391
            G PG PG           G  G KG++G +G+PG PGP G       VG PG PGP   +
Sbjct: 1126 GLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK 1185

Query: 392  GPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPG 450
            G EG+ G  GLPG   PGP G  G +GP G  GL G   K G +GD GP GP G MG PG
Sbjct: 1186 GSEGIRGPSGLPGS--PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPG 1243

Query: 451  I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPG 507
              G  G  G+ GP G  G  GP G  G PG++GE G MGP G  GP G +G  GP G+PG
Sbjct: 1244 FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303

Query: 508  SIG-----------------LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQ 546
              G                 L G PG PG  G  G  GE G  GA G EGPPGK    G 
Sbjct: 1304 PAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGP 1363

Query: 547  PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP 606
            PGPKGD G  G KG  G++G  G  G  G+ G MGP G        PPGP G+RG PG P
Sbjct: 1364 PGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVG--------PPGPAGERGHPGAP 1415

Query: 607  GFKGEPGL-SIRGPKG------------------------------VQGPRGPVGAPGLK 635
            G  G PGL  + G  G                              +Q P     APG  
Sbjct: 1416 GPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP 1475

Query: 636  GDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            G   PG  G  G PG PG  GL G +G  G +G PGVRG PG  G +G    G  G+ G 
Sbjct: 1476 GP--PGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGL 1533

Query: 695  KGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIG 754
             G PGP GPPGYG  G  G  G QG PG  G      PG  G+ G+ G        G + 
Sbjct: 1534 PGPPGPQGPPGYGKMGATGPMGQQGIPGIPGP-----PGPMGQPGKAGHCNPSDCFGAMP 1588

Query: 755  -EPGSPGKQGLQGPKG 769
             E   P  + ++GP G
Sbjct: 1589 MEQQYPPMKTMKGPFG 1604



 Score =  383 bits (984), Expect = e-106
 Identities = 285/749 (38%), Positives = 323/749 (43%), Gaps = 224/749 (29%)

Query: 242  CEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG-PGGIPGYKGDKGERG-- 298
            C  G  G  G PG  G  G+ GE GP G PG    G  G  G PGG PG KGDKG  G  
Sbjct: 426  CVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIP 485

Query: 299  -------ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG-------------F 338
                   + GKPG+KG+KG P    P  P G Q   G PG PGPKG              
Sbjct: 486  GKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGI 545

Query: 339  QGNKGEPGPP--------------------GPYGSPG--APGI-GQQGIKGERGQEGRPG 375
            QG KGE G P                    G  GSPG   PG+ G+ G+ G +G++G  G
Sbjct: 546  QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFG 605

Query: 376  APGPIGVGEPGQPGPRGPEGVPGERGLPGE----------------GFPGPKGEKGSEGP 419
              GP   G PG PGP GP G+ G +G P E                  PGP GEKG  GP
Sbjct: 606  EAGP--AGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663

Query: 420  TG-----PQGLQG-LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP------- 465
             G      QG  G   +KG+KGD G  G  G  G  G  G  GE G+QGP GP       
Sbjct: 664  PGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDG 723

Query: 466  --------------------PGP---QGPAGQGLPGSKGEVGQMGPTGPRG--------- 493
                                PGP   QGP G G PG  G+ G  G  GP G         
Sbjct: 724  CTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPG 783

Query: 494  PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE------AGLPGARGPEGPPGKGQP 547
            P G GVQGP+GEPG+ GLPG  G+PG  G  G  GE       G+ GA GP GPPG    
Sbjct: 784  PPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVS 843

Query: 548  GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------------------------- 580
            GP G +G++G  G +G  G  GP G KGEPG                             
Sbjct: 844  GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQP 903

Query: 581  GPFGMPGTSIPGPPGPKGDRGGPGIP---GFKGEPGL---------------SIRG---- 618
            GP G PG  IPGPPGP G  G  G+P   G  G+PGL               SI G    
Sbjct: 904  GPQGPPG--IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQ 961

Query: 619  ----------PKGVQGPRGPVGAPGL------------------KGDGYPGVPGPRGLPG 650
                       KG +G +G  G PGL                  +GD   G PG  G PG
Sbjct: 962  GQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPG 1021

Query: 651  PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----------------VGTQGPKGDTGQ 694
             PGP GL   G  G +G PG+RG PGP GP G                 G +G  G TG 
Sbjct: 1022 LPGPPGL--PGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGD 1079

Query: 695  KGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGD 743
            KG PGPPG PGY       G  GIKGE+G  G  G KG  G     GLPG  G  G RG+
Sbjct: 1080 KGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGE 1139

Query: 744  VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G +G+ GE G+ G  G+ G  GP G  G
Sbjct: 1140 RGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168



 Score =  380 bits (977), Expect = e-105
 Identities = 276/732 (37%), Positives = 320/732 (43%), Gaps = 219/732 (29%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPG---------NAQKGEAGERGPGGIPGYKGDK 294
            +G PG  G  G  G+PG+KG  GP G PG         + Q+G+ G RG  G  G +G+K
Sbjct: 811  RGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEK 870

Query: 295  GERGECG------------------------KPGIKGDKGSPGPYGPKGPRGIQGITGP- 329
            GE GEC                         +PG +G  G PGP GP G  G+QG+ G  
Sbjct: 871  GEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNN 930

Query: 330  --PGDP-------------------------------------GPKGFQGNKGEPG---- 346
              PG P                                     G KG QG  G PG    
Sbjct: 931  GLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNC 990

Query: 347  ----------------------PPGPYGSPGAPGI----GQQGIKGERGQEGRPGAPGPI 380
                                   PG  GSPG PG     GQ+G +G  G  G PG PGPI
Sbjct: 991  AQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPI 1050

Query: 381  GV-GEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKG 435
            G  G PG  G  G  G+ GERGL G    +G PGP G+ G  G TGP GL G  IKGE+G
Sbjct: 1051 GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPG--IKGERG 1108

Query: 436  DIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494
              G  G +G  G PG      +G+ GP GP GP+G  G QG  G KG+ G  G  G  GP
Sbjct: 1109 YTGSAGEKGEPGPPG-----SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163

Query: 495  VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEG 554
                  GP G PG +G PG PG   E G+ G +G +GLPG+ GP GPPG    GP G +G
Sbjct: 1164 -----PGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGI--QGPAGLDG 1216

Query: 555  KKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG 613
              G  G  G RG PGP GP   PG+MGP G  G T  PG PGPKGD G PG PG  G PG
Sbjct: 1217 LDGKDGKPGLRGDPGPAGP---PGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPG 1273

Query: 614  LS----IRGPKGVQGPRGPVGAPG--------------LKGD----------GYPGVPGP 645
                    GP+G  GP G VG PG              LKGD          G PG PGP
Sbjct: 1274 AEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGP 1333

Query: 646  RGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGP 703
             G PGPPG  G  G  G  G  G+ G  GPPGP G P   G +G  G+ G+ G+PG PG 
Sbjct: 1334 PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGK 1393

Query: 704  PG----YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEH-------------------- 738
             G     G  G  GE+G  G PGP G+ G  G+PG  G+                     
Sbjct: 1394 SGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDE 1453

Query: 739  -------------------GERGDVGKKGDKGEIGEPGSPG---------KQGL------ 764
                               G  G  GK G  G  G PGSPG         +QGL      
Sbjct: 1454 RMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGL 1513

Query: 765  ---QGPKGDLGL 773
               +G KGD+G+
Sbjct: 1514 PGTKGEKGDIGI 1525



 Score =  370 bits (949), Expect = e-102
 Identities = 259/621 (41%), Positives = 306/621 (49%), Gaps = 118/621 (19%)

Query: 244 KGDPGDPGPPGTHGNPGIKGE--------------RGPKGNPGNAQKGEAGERGPGGIPG 289
           KG+ G PGPPG+ G  G +G                GPKG     +KGE+G  GP G+PG
Sbjct: 339 KGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKG-----EKGESGALGPSGLPG 393

Query: 290 YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349
             G+KG++GE G  GIKG  G PG  G  G   + G  G  GDPG  G +G  GEPGPPG
Sbjct: 394 STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG 453

Query: 350 -----PYGSPGAPGI--GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRG---------- 392
                  G PG PG   G  G KG++G  G PG  GP   G+PG+PG +G          
Sbjct: 454 LPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGP--GGKPGKPGVKGEKGDPCEVCP 511

Query: 393 --PEGVPGERGLPGEGFPGPKGEKGSEGPT-GPQGLQGLSIKGEKGD------------- 436
             PEG     GLPG+  PGPKGE G   P  G  G+QG  IKGEKG+             
Sbjct: 512 TLPEGFQNFVGLPGK--PGPKGEPGDPVPARGDPGIQG--IKGEKGEPCLSCSSVVGAQH 567

Query: 437 -IGPVGPQGPMGIPGI---------------GSQGEQGIQGPIGPPGPQGPAG-QGLPGS 479
            +   G  G +G PG                G +G  G  GP G PGP GP G  G+ G+
Sbjct: 568 LVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGA 627

Query: 480 KGEVGQMGPTGPR---GPVGI----GVQGPKGEPG--SIGLPGQPGVPGEDGAAGKKGEA 530
           KGE  +  P       G V +    G  G KGEPG    GLPG+ G  GE G  G+KG+A
Sbjct: 628 KGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDA 687

Query: 531 GLPGARGPEGPPGK----GQPGPKGDEGKKGSKGN--------QG----QRGLPGPEGPK 574
           G PG  G  G  G+    G+PG +G  G KG KG+        QG      G PG  GPK
Sbjct: 688 GNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPK 747

Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634
           GE G  G  G PG   PG PG  G +G PG+ G +GEPG   R   GVQGP+G  GAPGL
Sbjct: 748 GEQGPEG-VGRPGK--PGQPGLPGVQGPPGLKGVQGEPGPPGR---GVQGPQGEPGAPGL 801

Query: 635 KGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
              G  G+PGPRG PGP         G+ GA+G PGV+G  GP GP G    GP G  GQ
Sbjct: 802 --PGIQGLPGPRGPPGP--------TGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQ 851

Query: 695 KGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG-EHGERGDVGKKGDKGE 752
           +G  G  G PG  G +G KGE G    P     +  G+PG  G   G     G +G  G 
Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911

Query: 753 IGEPGSPGKQGLQGPKGDLGL 773
            G PG PG  GLQG  G+ GL
Sbjct: 912 PGPPGPPGVPGLQGVPGNNGL 932



 Score =  307 bits (786), Expect = 4e-83
 Identities = 242/635 (38%), Positives = 283/635 (44%), Gaps = 164/635 (25%)

Query: 287 IPGYKGDKGERG----------ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336
           + G    K ERG          EC  P + G + S     P GP+G +G  G PG PG  
Sbjct: 293 LTGRISQKAERGAKVHQETAADEC-PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGS- 350

Query: 337 GFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEG 395
             +G KG  G      SP AP    +G KGE+G+ G  G  G P   GE GQ G +G  G
Sbjct: 351 --KGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGG 408

Query: 396 VPGERGLPG-EGFP------GPKGEKGSEGPTGPQGL------------QGLSIKGEKGD 436
           + G  G PG +G P      GPKG+KG  G  GP+GL             G+ + G  GD
Sbjct: 409 IKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGD 468

Query: 437 IGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-------------------GLP 477
             P GP GP G    GS G  G +GP G PG  G  G+                   GLP
Sbjct: 469 --PGGPPGPKG--DKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLP 524

Query: 478 GSKGEVGQMG-PTGPRGPVGI-GVQGPKGEP--------------------GSIGLP--G 513
           G  G  G+ G P   RG  GI G++G KGEP                    G +G P  G
Sbjct: 525 GKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFG 584

Query: 514 QPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR-------- 565
            PG+PG  G  G KGE G  G  GP G P  G PGP G  G KG+KG   +         
Sbjct: 585 LPGLPGRAGVPGLKGEKGNFGEAGPAGSP--GPPGPVGPAGIKGAKGEPCEPCPALSNLQ 642

Query: 566 -------GLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGE 611
                   LPGP G KGEPG  G FG+PG         + G  G  G+ G PG PG  G 
Sbjct: 643 DGDVRVVALPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701

Query: 612 PGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVP----------GPRGLPGPPGPMGLRGVG 661
           PGLS  G  GVQGP GP G    KGDG    P          G  G PGP G  G  GVG
Sbjct: 702 PGLS--GEPGVQGPAGPKGE---KGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVG 756

Query: 662 DTGAKGE---PGVRGPP------GPSGPRGVGTQGPKGDTGQ------KGLPGPPGPPG- 705
             G  G+   PGV+GPP      G  GP G G QGP+G+ G       +GLPGP GPPG 
Sbjct: 757 RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGP 816

Query: 706 ------YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGS- 758
                  GS G+KG  GP G PG   +   G  GQ+G+ G RG  G+KG +GE GEPG  
Sbjct: 817 TGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGEC 876

Query: 759 -------------PGKQGL-------QGPKGDLGL 773
                        PG  GL        GP+G  G+
Sbjct: 877 SCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911



 Score =  291 bits (746), Expect = 2e-78
 Identities = 194/492 (39%), Positives = 227/492 (46%), Gaps = 111/492 (22%)

Query: 243  EKGDPGDPGP---PGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
            EKG+PG PG    PG  G  G +GERGP+GN G  +KG+ G +G  G PG  G  G  G+
Sbjct: 1115 EKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSG--EKGDQGFQGQPGFPGPPGPPGFPGK 1172

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP---GPKGFQGNKGEPGPPGPYGSPGA 356
             G PG  G +   G  G +GP G+ G  GPPG P   GP G  G  G+ G PG  G PG 
Sbjct: 1173 VGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGP 1232

Query: 357  PG-IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPK 411
             G  G  G  G +G+ G PG PGP   G+ G+PGP G  G PG  G PG    +G PGP 
Sbjct: 1233 AGPPGLMGPPGFKGKTGHPGLPGP--KGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPP 1290

Query: 412  GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG--------------------- 450
            G  G  GP G  G  G+S  G KGD G  G +G  G+PG                     
Sbjct: 1291 GHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAG 1350

Query: 451  -IGSQGEQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGV 499
              G  G+QG  GP GP G  G AGQ          G+PG  G+ G MGP GP GP   G 
Sbjct: 1351 KEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPA--GE 1408

Query: 500  QGPKGEPGSIGLPGQPGVPGEDG------------------------------------A 523
            +G  G PG  G PG PGVPG  G                                     
Sbjct: 1409 RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEM 1468

Query: 524  AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582
            A   G  G PG  G  G PG  G PG  G  G++G +G  G RGLPG +G KG+ GI   
Sbjct: 1469 AAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI--- 1525

Query: 583  FGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPG 641
             G+ G   +PGPPGP+G       PG+         G  G  GP G  G PG+     PG
Sbjct: 1526 -GIAGENGLPGPPGPQGP------PGY---------GKMGATGPMGQQGIPGI-----PG 1564

Query: 642  VPGPRGLPGPPG 653
             PGP G PG  G
Sbjct: 1565 PPGPMGQPGKAG 1576



 Score =  152 bits (383), Expect = 2e-36
 Identities = 105/262 (40%), Positives = 128/262 (48%), Gaps = 51/262 (19%)

Query: 537 GPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLP--------GPEGPKGEPGIMGPFGMPG 587
           GP+G  G +G PGP G +G+KG++GN   R  P        GP+G KGE G +GP G+  
Sbjct: 334 GPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGL-- 391

Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRG 647
              PG  G KG +G  G  G KG PG    G  G  G    +G  G KGD  PG  GP G
Sbjct: 392 ---PGSTGEKGQKGEKGDGGIKGVPGKP--GRDGRPGEICVIGPKGQKGD--PGFVGPEG 444

Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY- 706
           L G PGP GL G    G  G PG      P GP      GPKGD G  G+PG  GP G  
Sbjct: 445 LAGEPGPPGLPGPPGIGLPGTPG-----DPGGP-----PGPKGDKGSSGIPGKEGPGGKP 494

Query: 707 GSQGIKGEQG---------PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPG 757
           G  G+KGE+G         P+GF    G     LPG+ G  GE GD         +   G
Sbjct: 495 GKPGVKGEKGDPCEVCPTLPEGFQNFVG-----LPGKPGPKGEPGD--------PVPARG 541

Query: 758 SPGKQGLQGPKGDLGLTKEEII 779
            PG QG++G KG+  L+   ++
Sbjct: 542 DPGIQGIKGEKGEPCLSCSSVV 563



 Score =  109 bits (273), Expect = 1e-23
 Identities = 71/201 (35%), Positives = 90/201 (44%), Gaps = 29/201 (14%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGE-------------------RG 283
            E+G PG PGP G+ G PG+ G  G   N    ++    E                     
Sbjct: 1408 ERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPME 1467

Query: 284  PGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-----GF 338
                PG  G  G+ G  G+PG  G  G PG  G +G +G+ G+ G PG  G K     G 
Sbjct: 1468 MAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGI 1527

Query: 339  QGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVP 397
             G  G PGPPGP    G PG G+ G  G  GQ+G PG PGP G +G+PG+ G   P    
Sbjct: 1528 AGENGLPGPPGP---QGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCF 1584

Query: 398  GERGLPGEGFPGPKGEKGSEG 418
            G   +  + +P  K  KG  G
Sbjct: 1585 GAMPME-QQYPPMKTMKGPFG 1604


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  426 bits (1096), Expect = e-119
 Identities = 265/594 (44%), Positives = 320/594 (53%), Gaps = 69/594 (11%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGE 299
            +G PGD GPPG +G  G+KG+ G +G PG       +G+ G  GP G PG +G  G +G 
Sbjct: 909  EGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGF 968

Query: 300  CGKPGIKG------DKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353
             G+PG+ G      D G PGP G +G  G  G+ G PG  G KG +G  G PG PGP GS
Sbjct: 969  PGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGS 1028

Query: 354  PGAPGI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGP 410
             G PG+ G  G  GE G +G PG+ GP G+ G  G+ GPRGP+G  GE+G  G +G PGP
Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088

Query: 411  KGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQ 469
            +G  G  G  G  G +G L  +G  G  GP GP G  G+PG    G QG QGPIGPPG  
Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPG--EPGPQGPQGPIGPPGEM 1146

Query: 470  GPAGQ-------GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPGQP 515
            GP G        GLPG  G  G +GP G  G  G+       G++G  G  G  GL G  
Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206

Query: 516  GVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574
            G PG DG  G+KG+ GL G  GP GPPG  G  GP+G  GK+G KG  G +G  G +G  
Sbjct: 1207 GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQL 1266

Query: 575  GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPG---FKGEPGLS-IRGPKGVQGPRGPVG 630
            GE G+ G  G PGT  PGP G +G  G  G PG    +GEPGL+   G KG+ GP GP G
Sbjct: 1267 GEMGVPGDPGPPGT--PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPG 1324

Query: 631  APGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGV----GT 685
              G KG+   G  G     GPPGP G RG VGD G +GEPG  G PG  G +G+    G 
Sbjct: 1325 PKGEKGE--QGEDGKA--EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQ 1380

Query: 686  QGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPGPKGTMGH------ 729
            QG  G  G +G PGP G  G           G+ G +G QG QG PGP+G +G       
Sbjct: 1381 QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI 1440

Query: 730  ----GLPG---QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
                GLPG   Q G+ GE+GD G  G  G  G+ G+PG  GL G +G  G   E
Sbjct: 1441 AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGE 1494



 Score =  424 bits (1091), Expect = e-118
 Identities = 270/592 (45%), Positives = 316/592 (53%), Gaps = 75/592 (12%)

Query: 248  GDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKG 307
            G+ GPPG  GNPG  G  GP G PG    G+ G  GP G PG KG KG  G  G+PG+KG
Sbjct: 796  GERGPPGLDGNPGELGLPGPPGVPGLI--GDLGVLGPIGYPGPKGMKGLMGSVGEPGLKG 853

Query: 308  DKGS---------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---PGPPGPYGSPG 355
            DKG          PG  G KG +G+ G  G  G PGP G  G+KG    PGPPGP G PG
Sbjct: 854  DKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPG 913

Query: 356  APGIGQQGIKGERGQEGRPGA---PGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGP 410
               IG  G  G  G +G+PGA   PGP G +G  G  GP GP G PG  G PG +GFPG 
Sbjct: 914  --DIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR 971

Query: 411  ------KGEKGSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGI----GSQGE 456
                  KGE G  G  GP G QG    + + GE G +G  G +G MG PG+    GS G 
Sbjct: 972  PGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGH 1031

Query: 457  QGIQGPIGPPG---PQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGL 511
             G+ G +G PG   PQGP G +G PG +G  G+ GP GP GP G  G +G KG PG  G 
Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR 1091

Query: 512  PGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGP 570
            PG+PG  G  G  G  G  G PG  GP GPPG KG PG  G +G +G  G  G+ G  GP
Sbjct: 1092 PGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGP 1151

Query: 571  EGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPV 629
             G  GEPG+ G  GM G   P G PG +G  G  G PG +G+ G    GP G++G RG  
Sbjct: 1152 PGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM--GPDGLKGDRGDP 1209

Query: 630  GAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGE---------- 668
            G  G  G+ G  G+ G  G PGPPG  G+RG           G TGAKG           
Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269

Query: 669  --PGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725
              PG  GPPG  GP+G  G+ GP G  G+ G  G PG  GY   G KG  GP G PGPKG
Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGY--DGHKGIVGPLGPPGPKG 1327

Query: 726  TMGHG-----LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              G         G  G  G+RG VG +GD+GE G+PG PG++G+QG +G  G
Sbjct: 1328 EKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPG 1379



 Score =  422 bits (1085), Expect = e-118
 Identities = 268/611 (43%), Positives = 314/611 (51%), Gaps = 90/611 (14%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGE--- 299
            KG+PGDPG PG  G  G  G  G  G PG   +KG+ G  GP G+PG KG  G  G    
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 300  CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359
             G PG  G +G PG  GP G RG +G  GP G  GP G QG++G  GPPGP G PG PG 
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG- 1096

Query: 360  GQQGIKGERGQ---EGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPGE---- 405
             QQG+ GERG     G PG PGP G        GEPG  GP+GP G PGE G  G     
Sbjct: 1097 -QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAV 1155

Query: 406  ---GFPGPKGEKGSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI---- 451
               G PG  G KG  GP G  G QGL        ++G+ G +GP G +G  G PG     
Sbjct: 1156 GEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEH 1215

Query: 452  GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIG 510
            G +G++G+ G  GPPGP G  G +G  G  G+ G+ G TG +G  G   QG  GE G  G
Sbjct: 1216 GEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY--QGQLGEMGVPG 1273

Query: 511  LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQG 563
             PG PG PG  G+ G  G  G PG  G +G PG       KG  GP G  G KG KG QG
Sbjct: 1274 DPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG 1333

Query: 564  Q----RGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619
            +     G PGP G +G  G  G  G PG   PG PG +G +G  G PG +G+PG    GP
Sbjct: 1334 EDGKAEGPPGPPGDRGPVGDRGDRGEPGD--PGYPGQEGVQGLRGKPGQQGQPGHP--GP 1389

Query: 620  KGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV------------ 660
            +G  GP+G  GA G KG        G  GV G +GLPGP G +G +G+            
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449

Query: 661  -GDTGAKGEPGVRGPPGPSGPRGV----------GTQGPKGDTGQKGLPGPPGPPGY--- 706
             G  G +GE G  G PGP GP G           G QGP G  G+ GLPG  GPPG    
Sbjct: 1450 DGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509

Query: 707  ----GSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGK 761
                G  G +GE G +G PG  G MG  G+ G  G  G  GD+G KG +G  G PG  GK
Sbjct: 1510 EGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGK 1569

Query: 762  QGLQGPKGDLG 772
            +G+ GP G LG
Sbjct: 1570 EGIVGPLGILG 1580



 Score =  421 bits (1082), Expect = e-117
 Identities = 264/580 (45%), Positives = 314/580 (54%), Gaps = 76/580 (13%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303
            KGD G PGPPG  G PGI G RGP+G PG           P G PG  G  G +G+ G P
Sbjct: 630  KGDCGLPGPPGLPGLPGIPGARGPRGPPG-----------PYGNPGLPGPPGAKGQKGDP 678

Query: 304  GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGPPGPYGSPGAPGI- 359
            G+   K   G  G  G  G+ G  GPPG  G KG+    G+ GE G PGP GSPGA G  
Sbjct: 679  GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP 738

Query: 360  GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414
            G+QG+ G  G  G  G+ G IG+    G PG  G RG  GVPG+RG  G  GFPG  GE+
Sbjct: 739  GRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGER 798

Query: 415  GSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI----------GSQGEQ 457
            G  G  G  G  GL        + G+ G +GP+G  GP G+ G+          G +GEQ
Sbjct: 799  GPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQ 858

Query: 458  GIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQP 515
            G+ G  G PG QG  G QGLPG  G  G+ GP G  G  G IG  GP   PG  G PG  
Sbjct: 859  GVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP---PGPEGFPGDI 915

Query: 516  GVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
            G PG++G  G KG+   PGARG  GP  +GQ GP+GDEG  G  G  G  G PG +G  G
Sbjct: 916  GPPGDNGPEGMKGK---PGARGLPGP--RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPG 970

Query: 576  EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635
             PG+ G  G PG   PG PGP G++G  G  G  GEPG  I G KG +G  GP G PG K
Sbjct: 971  RPGLDGVKGEPGD--PGRPGPVGEQGFMGFIGLVGEPG--IVGEKGDRGMMGPPGVPGPK 1026

Query: 636  GD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            G  G+PG+PG  G PG PGP      G  G++G PG+RG  G  GPR  G  GP G+ G 
Sbjct: 1027 GSMGHPGMPGGMGTPGEPGPQ-----GPPGSRGPPGMRGAKGRRGPR--GPDGPAGEQGS 1079

Query: 695  KGLPGPPGPPGY----GSQGIKGEQGP------QGFPGPKGTMG-HGLPGQKGEHGER-- 741
            +GL GPPGP G     G QG+ GE+G        G PGP G  G  GLPG+ G  G +  
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 742  ----GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
                G++G KG  G +GEPG PG+ G++G  G LG   E+
Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQ 1179



 Score =  415 bits (1066), Expect = e-115
 Identities = 254/583 (43%), Positives = 301/583 (51%), Gaps = 66/583 (11%)

Query: 245  GDPGDPGPPGTHG------------NPGIKGERGPKGNPGN----AQKGEAGERGPGGIP 288
            G+PG PGPPG  G            + G KG+ G  G  GN     +KG  G  GP G P
Sbjct: 661  GNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP 720

Query: 289  GYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348
            G +G  G  G  G  G  G +G PGP G  GP+G +G  G PG  G  G  G +G PG P
Sbjct: 721  GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVP 780

Query: 349  GPYGSPGAPGI----------GQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPE 394
            G  G  G PG           G  G  GE G  G PG PG IG    +G  G PGP+G +
Sbjct: 781  GKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMK 840

Query: 395  GVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPM 446
            G+ G  G PG       +G PG  G+ G +G  G QGL G    +G+ G +G VG +G +
Sbjct: 841  GLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI 900

Query: 447  GIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE 505
            G P  G  G +G  G IGPPG  GP G +G PG++G  G  G  GP G    G  GP G 
Sbjct: 901  GFP--GPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE--GPMGPPGA 956

Query: 506  PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGN 561
            PG  G PG+ G PG  G  G KGE G PG  GP G  G     G  G  G  G+KG +G 
Sbjct: 957  PGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGM 1016

Query: 562  QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG 621
             G  G+PGP+G  G PG+ G  G PG   PGP GP G RG PG+ G KG      RGP+G
Sbjct: 1017 MGPPGVPGPKGSMGHPGMPGGMGTPGE--PGPQGPPGSRGPPGMRGAKGR-----RGPRG 1069

Query: 622  VQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGP 680
              GP G  G+ GLKG      PGP+G PG PG  G+ G  G  G++G PG+ GP GP G 
Sbjct: 1070 PDGPAGEQGSRGLKGP-----PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGT 1124

Query: 681  RGV----GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQ 734
            +G+    G QGP+G  G  G  GP GPPG  G  G+ GE G +G  GP GT G  GL GQ
Sbjct: 1125 KGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQ 1184

Query: 735  KGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
            +GE G  GD G  G  G  G+ G PG  G  G KG  GL  E+
Sbjct: 1185 RGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGED 1227



 Score =  320 bits (821), Expect = 4e-87
 Identities = 204/463 (44%), Positives = 239/463 (51%), Gaps = 79/463 (17%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301
            E G  GD GP G  G  G +G+ GP G  G   Q+G  GE GP G PG  G +G  G+ G
Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSG 1246

Query: 302  KPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358
            K G KG    KG+ G  G  G  G+ G  GPPG PGPKG +G+ G  G PG  G+ G PG
Sbjct: 1247 KQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPG 1306

Query: 359  I----------------GQQGIKGERGQEGR-------PGAPGPIG----VGEPGQPGPR 391
            +                G +G KGE+G++G+       PG  GP+G     GEPG PG  
Sbjct: 1307 LAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYP 1366

Query: 392  GPEGVPGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVG 441
            G EGV G RG PG+          G+PGPKG KG+EGP G QG  G    G +G  G  G
Sbjct: 1367 GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAG--APGRRGVQGLQG 1424

Query: 442  PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQG 501
              GP G+  +G QG +GI GP G PG  G AGQ     +GE G  G  GP GP      G
Sbjct: 1425 LPGPRGV--VGRQGLEGIAGPDGLPGRDGQAGQ-----QGEQGDDGDPGPMGPA-----G 1472

Query: 502  PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG----PPGKGQPGPKGDEGKKG 557
             +G PG  GLPG  G PG  G +G  G+ G PG RG EG    P  +G+PG KG  G  G
Sbjct: 1473 KRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSG 1532

Query: 558  SKGNQGQRGLPGPEGPKGE---PGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG 613
              G  G  GL GP+GP G+    GI GP G PG     G  GP G  G  G+PG KG+ G
Sbjct: 1533 EMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKG 1592

Query: 614  LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMG 656
               RG  G+QGPRGP              PGPRG PGPPGP G
Sbjct: 1593 --SRGDWGLQGPRGP--------------PGPRGRPGPPGPPG 1619



 Score =  205 bits (521), Expect = 2e-52
 Identities = 124/285 (43%), Positives = 158/285 (55%), Gaps = 28/285 (9%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            ++G+PGDPG PG  G  G++G+ G +G PG+   G  G  GP G  G +G KG++G+ G 
Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHP--GPRGWPGPKGSKGAEGPKGKQGKAGA 1413

Query: 303  PG---IKGDKGSPGPYGPKGPRGIQGITGPPGDPG------PKGFQGNKGEPGPPGPYGS 353
            PG   ++G +G PGP G  G +G++GI GP G PG       +G QG+ G+PGP GP G 
Sbjct: 1414 PGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGK 1473

Query: 354  PGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKG 412
             G PG+      G  G +G PG  G  G+  PGQ GP G  G  G  GLPG +G PG KG
Sbjct: 1474 RGNPGVA-----GLPGAQGPPGFKGESGL--PGQLGPPGKRGTEGRTGLPGNQGEPGSKG 1526

Query: 413  EKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPG 467
            + G  G  G  G+ GL   KG  GDIG  G QGP G PG+    G  G  GI GP G PG
Sbjct: 1527 QPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPG 1586

Query: 468  PQGPAGQ----GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGS 508
            P+G  G     GL G +G  G  G  GP GP G  +Q  + + G+
Sbjct: 1587 PKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA 1631



 Score =  185 bits (469), Expect = 2e-46
 Identities = 113/255 (44%), Positives = 138/255 (54%), Gaps = 34/255 (13%)

Query: 238  KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297
            K  E  KG  G  G PG  G  G++G  GP+G  G  ++G  G  GP G+PG  G  G++
Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG--RQGLEGIAGPDGLPGRDGQAGQQ 1456

Query: 298  GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357
            GE      +GD G PGP GP G RG  G+ G PG  GP GF+G  G PG  GP       
Sbjct: 1457 GE------QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGP------- 1503

Query: 358  GIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKG 415
                    G+RG EGR G PG  G  G  GQPG  G  G PG  GL G +G PG  G KG
Sbjct: 1504 -------PGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKG 1556

Query: 416  SEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQG- 470
             +GP GP GL      G++G +GP+G  GP G+PG     GS+G+ G+QGP GPPGP+G 
Sbjct: 1557 IQGPRGPPGLM-----GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGR 1611

Query: 471  PAGQGLPGSKGEVGQ 485
            P   G PG   ++ Q
Sbjct: 1612 PGPPGPPGGPIQLQQ 1626



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 90/266 (33%), Positives = 99/266 (37%), Gaps = 71/266 (26%)

Query: 573 PKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP-------GFK---GEPGLSIRGPKGV 622
           P   PG       P T +P   G    R  P +P       G K   G       GPK  
Sbjct: 491 PAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPK-- 548

Query: 623 QGPRGPV--------------------------------------------GAPGLKGDG 638
             PR PV                                             +P     G
Sbjct: 549 SSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSG 608

Query: 639 YP------GVPGP--RGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG-VGTQGP 688
           Y         P P   G PGP G  GL G  G  G  G PG RGP GP GP G  G  GP
Sbjct: 609 YSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGP 668

Query: 689 KGDTGQKGLPG-PPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGK 746
            G  GQKG PG  PG    G++G  G  G  G PGP G  GH G PG  G  GE+   G+
Sbjct: 669 PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQ---GQ 725

Query: 747 KGDKGEIGEPGSPGKQGLQGPKGDLG 772
            G +G  G  G PG+QGL GP GD G
Sbjct: 726 PGPEGSPGAKGYPGRQGLPGPVGDPG 751


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  424 bits (1090), Expect = e-118
 Identities = 269/617 (43%), Positives = 305/617 (49%), Gaps = 93/617 (15%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
            G  G  G PG  G PG  G  G +G PGN   G  G +GP G PG  GDKG  G  G  G
Sbjct: 463  GKEGPVGLPGIDGRPGPIGPAGARGEPGNI--GFPGPKGPTGDPGKNGDKGHAGLAGARG 520

Query: 305  IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI----- 359
              G  G+ G  GP GP+G+QG  G  G PGP GFQG  G  GP G  G PG  G+     
Sbjct: 521  APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFG 580

Query: 360  --GQQGIKGERGQEGRPGAPGPIG----------------------VGEPGQPGPRGPEG 395
              G  G +GERG  G  GA GP G                      VG  G  GP GP G
Sbjct: 581  LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640

Query: 396  VPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG----------LSIKGEKGDIG 438
            +PGERG  G       +G PG +GE G+ G  G +G  G             +GE G  G
Sbjct: 641  LPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAG 700

Query: 439  PVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGEVGQMGPTGP 491
            P GP GP G P  G +GE G  GP G  GP G AGQ       G  G KGE G +GPTGP
Sbjct: 701  PAGPAGPRGSP--GERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGP 758

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQ 546
             G  G  G  GP G  GS G  G PG+ G  GAAG+ G  G  G  GP GPPG    +G 
Sbjct: 759  VGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGL 818

Query: 547  PGPKGDEGKKGSKGNQGQRGLP---GPEGPKGEPGIMGPFGMPG-------TSIPGPPGP 596
             GP+GD+G  G  G  G  G P   G +GP GE G  GP G PG         I G PG 
Sbjct: 819  RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS 878

Query: 597  KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGL 648
            +G+RG PG+ G  GEPG L I GP G +GP G VG+PG+ G       DG PG  GP G 
Sbjct: 879  RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938

Query: 649  PGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGP 700
             G PG  G RG    +G  GA G PG  GP GP+G  G     G  GP G  G  G  GP
Sbjct: 939  DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGP 998

Query: 701  PGPPGY-GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGER---GDVGKKGDKGEIGE 755
             GP G  G +G  GE+GP+G PG KG  G  GLPG  G HG++   G VG  G +G  G 
Sbjct: 999  SGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGP 1058

Query: 756  PGSPGKQGLQGPKGDLG 772
             G  GK G  G  G +G
Sbjct: 1059 SGPAGKDGRTGHPGTVG 1075



 Score =  423 bits (1088), Expect = e-118
 Identities = 268/615 (43%), Positives = 310/615 (50%), Gaps = 89/615 (14%)

Query: 245  GDPGDPGPPGTHGNPG---IKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGEC 300
            G PG  GP G  G PG     G +GP G+PG N  KG AG  G  G PG  G+ G +G  
Sbjct: 475  GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGD---PGPKGFQGNKGEPGPPGPYGSPGAP 357
            G  G++G KG  GP GP G +G+ G +GP G+   PG +G  G  G PGP GP G  G P
Sbjct: 535  GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPP 594

Query: 358  G-IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG----- 404
            G  G  G  G  G  G  G PGP G       VG  G  GP GP G+PGERG  G     
Sbjct: 595  GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK 654

Query: 405  --EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKGDIGPVGPQGPMGIPGIG 452
              +G PG +GE G+ G  G +G  G             +GE G  GP GP GP G PG  
Sbjct: 655  GEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG-- 712

Query: 453  SQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKG 504
             +GE G  GP G  GP G AGQ       G  G KGE G +GPTGP G  G  G  GP G
Sbjct: 713  ERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772

Query: 505  EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKG 560
              GS G  G PG+ G  GAAG+ G  G  G  GP GPPG    +G  GP+GD+G  G  G
Sbjct: 773  PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832

Query: 561  NQGQRGLPG---PEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKG 610
              G  G PG    +GP GE G  GP G PG         I G PG +G+RG PG+ G  G
Sbjct: 833  EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892

Query: 611  EPG-LSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG--- 659
            EPG L I GP G +GP G VG+PG+ G       DG PG  GP G  G PG  G RG   
Sbjct: 893  EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952

Query: 660  -VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKG 713
             +G  GA G PG  GP GP+G  G     G  GP G  G  G  GP GP G  G +G  G
Sbjct: 953  NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012

Query: 714  EQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGK---------------KGDKGEIGEPG 757
            E+GP+G PG KG  G  GLPG  G HG++G  G                 G  G  G PG
Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072

Query: 758  SPGKQGLQGPKGDLG 772
            + G  G++GP+G  G
Sbjct: 1073 TVGPAGIRGPQGHQG 1087



 Score =  423 bits (1087), Expect = e-118
 Identities = 263/589 (44%), Positives = 307/589 (52%), Gaps = 68/589 (11%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304
           G+PG  G  G  GN G  G  GP+G PG +  GE G+RGP G  G  G  G  G  G PG
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPS--GEEGKRGPNGEAGSAGPPGPPGLRGSPG 403

Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360
            +G  G+ G  G  GP G +G +GP G  GP G  G  GEPG  GP G PG+PG     G
Sbjct: 404 SRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG 463

Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPGERGLPGE-------GFPG 409
           ++G  G  G +GRPG  GP G  GEPG    PGP+GP G PG+ G  G        G PG
Sbjct: 464 KEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPG 523

Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGP 462
           P G  G++GP GPQG+QG      KG+ GP GP G  G+PG       +G  GE+G+ G 
Sbjct: 524 PDGNNGAQGPPGPQGVQG-----GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578

Query: 463 IGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGE 520
            G PGP GP G+ G PG  G  G  GP G RGP G  G  G KGEPG +G  G  G  G 
Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGP 638

Query: 521 DGAAGKKGEAGLPGARGPEGPPG-------------KGQPGPKGDEGKKGSKGNQGQRGL 567
            G  G++G AG+PG +G +G PG             +G PG  G  G  G+ G++G+ G 
Sbjct: 639 SGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGA 698

Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG---VQG 624
            GP GP G  G  G  G  G +  GP G  G  G  G PG KGE G   +GPKG   V G
Sbjct: 699 AGPAGPAGPRGSPGERGEVGPA--GPNGFAGPAGAAGQPGAKGERGA--KGPKGENGVVG 754

Query: 625 PRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG 682
           P GPVGA G  G +G PG  G RG  GPPG  G  G  G TG  G  G+ GPPGP GP G
Sbjct: 755 PTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAG 814

Query: 683 V-------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGH----G 730
                   G QGP G TG+ G  GPPG  G  G  G  G  GP G PGP+G +G     G
Sbjct: 815 KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG 874

Query: 731 LPGQKGEHG---ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           LPG +GE G     G VG+ G  G  G PG+ G  G  G  G  G   E
Sbjct: 875 LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGE 923



 Score =  417 bits (1073), Expect = e-116
 Identities = 269/604 (44%), Positives = 307/604 (50%), Gaps = 88/604 (14%)

Query: 248 GDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306
           G  GPPG  G PG +G +GP G PG   Q G AG RGP G PG     GE G  GKPG  
Sbjct: 97  GPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG---KAGEDGHPGKPGRP 153

Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IGQQ 362
           G++G  GP G +G  G  G+ G  G  G  G  G KG+PG PG  G PGAPG     GQ 
Sbjct: 154 GERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQT 213

Query: 363 GIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGE---KGSE 417
           G +G  G+ GR GAPGP G  G  G  GP GP G  G  G PG  G PGPKGE    G+ 
Sbjct: 214 GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273

Query: 418 GPTGPQGLQG-LSIKGEKGDIGPVGP------------------------QGPMGIPG-I 451
           GP GP G +G + + G  G +GP G                          GP GIPG +
Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333

Query: 452 GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIG 510
           G+ G  G +G +G PGP G  G+   G+KGE G  GP GP GP G  G +GP GE GS G
Sbjct: 334 GAAGATGARGLVGEPGPAGSKGES--GNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391

Query: 511 LPGQPGV---PGEDGAAGKKGEAGL---PGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQ 564
            PG PG+   PG  G  G  G AG+   PG+RG  GP   G  GP GD G+ G  G  G 
Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP--AGVRGPNGDAGRPGEPGLMGP 449

Query: 565 RGLPGPEGPKGEPGIMGPFGMPG-TSIPGP---------------PGPKGDRGGPGIPGF 608
           RGLPG  G  G  G  GP G+PG    PGP               PGPKG  G PG  G 
Sbjct: 450 RGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGD 509

Query: 609 KGEPGLS-------IRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659
           KG  GL+         G  G QGP GP G  G KG+ G PG PG +GLPGP GP G  G 
Sbjct: 510 KGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGK 569

Query: 660 VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-------YGS 708
            G+ G  GE G+ GP GP G RG     G  GP G  G +G  GPPGP G        G+
Sbjct: 570 PGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGA 629

Query: 709 QGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768
            G  G  GP G PG +G    G+PG KGE GE G  G+ G+ G  G  G+PG  G  GP 
Sbjct: 630 VGTAGPSGPSGLPGERGAA--GIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687

Query: 769 GDLG 772
           G  G
Sbjct: 688 GATG 691



 Score =  413 bits (1061), Expect = e-115
 Identities = 262/584 (44%), Positives = 300/584 (51%), Gaps = 62/584 (10%)

Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----------GEAGERGPGGIPGYKG 292
           E G PG+ G PG  G  G+ GERG  G PG A            G AG  G  G PG+ G
Sbjct: 200 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259

Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
             G +GE G  G  G  G  GP G  G  G+ G  GPPG+PG  G  G KG  G PG  G
Sbjct: 260 APGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAG 319

Query: 353 SPGAPG-------IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG 404
           +PG PG       +G  G  G RG  G PG  G  G  G  G+PG  GP+G PG  G   
Sbjct: 320 APGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSG--E 377

Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463
           EG  GP GE GS GP GP GL+G    G +G  G  G  G MG PG  G+ G  G++GP 
Sbjct: 378 EGKRGPNGEAGSAGPPGPPGLRG--SPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPN 435

Query: 464 GPPGPQGPAG----QGLPGSKGEVGQMGPTGPRG-------PVGIGVQGPKGEPGSIGLP 512
           G  G  G  G    +GLPGS G +G  G  GP G       P  IG  G +GEPG+IG P
Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFP 495

Query: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQ---R 565
           G  G  G+ G  G KG AGL GARG  GP G    +G PGP+G +G KG +G  G    +
Sbjct: 496 GPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQ 555

Query: 566 GLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQ 623
           GLPGP GP GE G  G  G+ G   +PGP GP+G+RG PG  G  G  G +  RGP G  
Sbjct: 556 GLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPP 615

Query: 624 GPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP---PGPSG 679
           GP G  G PG+ G  G  G  GP GLPG  G  G+   G  G KGEPG+RG    PG  G
Sbjct: 616 GPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGI--PGGKGEKGEPGLRGEIGNPGRDG 673

Query: 680 PRG----VGTQGPKGDTGQKGLPGPPGPPG----YGSQGIKGE---QGPQGFPGPKGTMG 728
            RG    VG  GP G TG +G  G  GP G     GS G +GE    GP GF GP G  G
Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAG 733

Query: 729 HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
              PG KGE G +G  G+ G  G  G  G+ G  G  GP G  G
Sbjct: 734 Q--PGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG 775



 Score =  412 bits (1060), Expect = e-115
 Identities = 260/598 (43%), Positives = 294/598 (49%), Gaps = 97/598 (16%)

Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN--------------------AQKGEAGERG 283
           +G+ G PGPPG  G  G  G  GP G PG                        G  G RG
Sbjct: 41  RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100

Query: 284 PGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG 343
           P G  G  G +G +G  G+PG  G  G  G  GP GP G  G  G PG PG     G +G
Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR---PGERG 157

Query: 344 EPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERG 401
             GP G  G PG PG+ G +GI+G  G +G  G PG  GV GEPG PG  G  G  G RG
Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217

Query: 402 LPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGE 456
           LPGE    G PGP G +GS+G  GP            G  GP+G  GP G PG  G +GE
Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGP-----------VGPAGPIGSAGPPGFPGAPGPKGE 266

Query: 457 QGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQP 515
            G  G  GP GP GP G+ GLPG  G VG      P  P   G+ G KG  G  G+ G P
Sbjct: 267 IGAVGNAGPAGPAGPRGEVGLPGLSGPVGP-----PGNPGANGLTGAKGAAGLPGVAGAP 321

Query: 516 GVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575
           G+PG  G  G  G AG  GARG       G+PGP G +G+ G+KG  G  G  GP GP G
Sbjct: 322 GLPGPRGIPGPVGAAGATGARGL-----VGEPGPAGSKGESGNKGEPGSAGPQGPPGPSG 376

Query: 576 EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGL 634
           E G  GP G  G++  GPPGP G RG PG  G  G  G   + GP G +G  GP G  G 
Sbjct: 377 EEGKRGPNGEAGSA--GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGP 434

Query: 635 KGD----GYPGVPGPRGLPGPP---------GPMGLRG-------VGDTGAKGEPGVRGP 674
            GD    G PG+ GPRGLPG P         GP+GL G       +G  GA+GEPG  G 
Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGF 494

Query: 675 PGPSGPRG-------------VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGP---- 717
           PGP GP G              G +G  G  G  G  GPPGP G   QG KGEQGP    
Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV--QGGKGEQGPPGPP 552

Query: 718 --QGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             QG PGP G  G  G PG++G HGE G  G  G +GE G PG  G  G  GP G  G
Sbjct: 553 GFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG 610



 Score =  410 bits (1053), Expect = e-114
 Identities = 261/598 (43%), Positives = 296/598 (49%), Gaps = 88/598 (14%)

Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGY-------------- 290
           G  G  GPPG  G PG KGE G  GN G A  G AG RG  G+PG               
Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPA--GPAGPRGEVGLPGLSGPVGPPGNPGANG 304

Query: 291 ----KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG 346
               KG  G  G  G PG+ G +G PGP G  G  G +G+ G PG  G KG  GNKGEPG
Sbjct: 305 LTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPG 364

Query: 347 PPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPG----PIGVGEPGQPGPRGPEGVPGERG 401
             GP G PG  G  G++G  GE G  G PG PG    P   G PG  G  G  G PG RG
Sbjct: 365 SAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRG 424

Query: 402 LPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGS 453
             G  G  GP G+ G  G  G  G +GL   G  G+IGP G +GP+G+PG       IG 
Sbjct: 425 ASGPAGVRGPNGDAGRPGEPGLMGPRGL--PGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482

Query: 454 QGEQGIQGPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRG-PVG 496
            G +G  G IG PGP+GP G                +G PG  G  G  GP GP+G   G
Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542

Query: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK---GEAGLPGARGPEGPPGKGQPGPKGDE 553
            G QGP G PG  GLPG  G  GE G  G++   GE GLPG  GP G   +G PG  G  
Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGE--RGPPGESGAA 600

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
           G  G  G++G  G PGP+G KGEPG++G  G  G S  GP G  G+RG  GIPG KGE  
Sbjct: 601 GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS--GPSGLPGERGAAGIPGGKGE-- 656

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-------VGDTGAK 666
                 KG  G RG +G PG   DG  G PG  G PGP G  G RG        G  G +
Sbjct: 657 ------KGEPGLRGEIGNPG--RDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPR 708

Query: 667 GEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQ 718
           G PG RG  GP+GP G     G  G  G  G++G  GP G  G     G  G  G  GP 
Sbjct: 709 GSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPN 768

Query: 719 GFPGPKGTMGHGLP----GQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           G PGP G+ G G P    G  G  G  G  G  G  G  G PG  GK+GL+GP+GD G
Sbjct: 769 GPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826



 Score =  317 bits (812), Expect = 4e-86
 Identities = 214/520 (41%), Positives = 240/520 (46%), Gaps = 118/520 (22%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGEC 300
            +G  G PGP G  G PG+ G  G  G  G +  G  GERG  GIPG KG+KGE   RGE 
Sbjct: 609  RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS--GLPGERGAAGIPGGKGEKGEPGLRGEI 666

Query: 301  GKPGIKGDKGSPGPYGPKGP------RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354
            G PG  G +G+PG  G  GP      RG  G  GP G  GP+G  G +GE GP GP G  
Sbjct: 667  GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726

Query: 355  GAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGER 400
            G  G        G++G KG +G+ G  G  GP+G        G PG  G RG  G PG  
Sbjct: 727  GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786

Query: 401  GLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGI---PGI-- 451
            G PG     G PGP G  G  GP GP G +GL  +G +GD GPVG  G +G    PG   
Sbjct: 787  GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGL--RGPRGDQGPVGRTGEVGAVGPPGFAG 844

Query: 452  --GSQGEQGIQGPIGPPGPQGPAGQ----GLPGSKGE---------------VGQMGPTG 490
              G  GE G  GP G PGPQG  G     GLPGS+GE               +G  GP G
Sbjct: 845  EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904

Query: 491  PRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQ 546
             RGP G     GV G  GE G  G PG  G PG DG  G KGE G PG  GP G    G 
Sbjct: 905  ARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG--AAGA 962

Query: 547  PGPKGDEGKKGSKGNQGQRGLPGPEGP------------------KGEPGIMGPFGMPGT 588
            PGP G  G  G  GN+G+ G  GP GP                  KGEPG  GP G+PG 
Sbjct: 963  PGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGL 1022

Query: 589  S-------IPGPPGPKGDRGGPGI------------------PGFKGEPGL----SIRGP 619
                    +PG  G  GD+G PG                    G  G PG      IRGP
Sbjct: 1023 KGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGP 1082

Query: 620  KGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG 659
            +G QGP GP G PG         PGP G+ G     G  G
Sbjct: 1083 QGHQGPAGPPGPPG--------PPGPPGVSGGGYDFGYDG 1114



 Score =  314 bits (805), Expect = 3e-85
 Identities = 198/466 (42%), Positives = 240/466 (51%), Gaps = 55/466 (11%)

Query: 334 GPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGE--PGQPGPR 391
           GP G +G +GE GPPGP G        + G  G  G  G PG PGP G+G     Q   +
Sbjct: 33  GPAGDRGPRGERGPPGPPG--------RDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGK 84

Query: 392 GPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPG 450
           G    PG  GL G     P+G  G+ G  GPQG QG + + GE G  GP G +GP G PG
Sbjct: 85  GVGLGPGPMGLMG-----PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG 139

Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSI 509
               GE G  G  G PG +G  G QG  G  G  G  G  G RG  G+   G KG+PG+ 
Sbjct: 140 --KAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL--DGLKGQPGAP 195

Query: 510 GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQR 565
           G+ G+PG PGE+G  G+ G  GLPG RG  G PG    +G  G  G  G  G  G+ G  
Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255

Query: 566 GLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGP 625
           G PG  GPKGE G +G  G  G     P GP+G+ G PG+ G  G PG    G  G+ G 
Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAG-----PAGPRGEVGLPGLSGPVGPPGNP--GANGLTGA 308

Query: 626 RGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV-------------GDTGAKGEPGVR 672
           +G  G PG+ G   PG+PGPRG+PGP G  G  G              G++G KGEPG  
Sbjct: 309 KGAAGLPGVAGA--PGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSA 366

Query: 673 GPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGL 731
           GP GP GP G   +G +G  G+ G  GPPGPPG     ++G  G +G PG  G  G  G 
Sbjct: 367 GPQGPPGPSG--EEGKRGPNGEAGSAGPPGPPG-----LRGSPGSRGLPGADGRAGVMGP 419

Query: 732 PGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
           PG +G  G  G  G  GD G  GEPG  G +GL G  G++G   +E
Sbjct: 420 PGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE 465



 Score =  276 bits (707), Expect = 6e-74
 Identities = 176/404 (43%), Positives = 204/404 (50%), Gaps = 46/404 (11%)

Query: 245  GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300
            G  G  GP G  G PG KGERG KG  G        G  G  GP G  G  G  G RG+ 
Sbjct: 721  GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780

Query: 301  GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-- 358
            G PG+ G  G+ G  GP GP GI G  GPPG  G +G +G +G+ GP G  G  GA G  
Sbjct: 781  GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP 840

Query: 359  --IGQQGIKGERGQEGRPGAPGPIGV-GEPG---QPGPRGPEGVPGERGLPGE----GFP 408
               G++G  GE G  G PG PGP G+ G PG    PG RG  G+PG  G  GE    G  
Sbjct: 841  GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIA 900

Query: 409  GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP-- 465
            GP G +G  G  G  G+ G    GE G  G  G  GP G  G  G +GE+G  G IGP  
Sbjct: 901  GPPGARGPPGAVGSPGVNGAP--GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958

Query: 466  ----PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPG 513
                PGP GP G  G  G++GE G  GP GP G VG        G++G KGEPG  G  G
Sbjct: 959  AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018

Query: 514  QPGVPGEDGA------AGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGL 567
             PG+ G +G       AG  G+ G PG+ GP GP  +G  GP G  GK G  G+ G  G 
Sbjct: 1019 LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP--RGPAGPSGPAGKDGRTGHPGTVGP 1076

Query: 568  PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGE 611
             G  GP+G     GP G PG   PGPPGP G  GG    G+ G+
Sbjct: 1077 AGIRGPQGHQ---GPAGPPGP--PGPPGPPGVSGGGYDFGYDGD 1115



 Score =  222 bits (566), Expect = 1e-57
 Identities = 141/306 (46%), Positives = 157/306 (51%), Gaps = 29/306 (9%)

Query: 244  KGDPGDPGPPGTHGN------PGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGE 296
            +G  GD GP G  G       PG  GE+GP G  G A   G  G +G  G PG  G  G 
Sbjct: 819  RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS 878

Query: 297  RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356
            RGE G PG+ G  G PGP G  GP G +G  G  G PG  G  G  G  G PG  G PG 
Sbjct: 879  RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938

Query: 357  PGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP-GPKGEK 414
               GQ G KGERG    PG  GP+G  G PG  GP GP G  G RG  G   P GP G  
Sbjct: 939  D--GQPGHKGERGY---PGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993

Query: 415  GSEGPTGPQGLQGLSIKGEKGDIGP------VGPQGPMGIPGI-GSQGEQGIQGPIGPPG 467
            G  GP+GPQG++G   KGE G+ GP       G  G  G+PGI G  G+QG  G +GP G
Sbjct: 994  GPRGPSGPQGIRG--DKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051

Query: 468  PQGPAGQGLPGSK----GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523
            P+GPAG   P  K    G  G +GP G RGP   G QGP G PG  G PG PGV G    
Sbjct: 1052 PRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQ--GHQGPAGPPGPPGPPGPPGVSGGGYD 1109

Query: 524  AGKKGE 529
             G  G+
Sbjct: 1110 FGYDGD 1115



 Score =  159 bits (403), Expect = 1e-38
 Identities = 98/229 (42%), Positives = 110/229 (48%), Gaps = 33/229 (14%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301
            E G  G  GPPG  G PG  G  G  G PG A + G  G  GP G  G  G KGERG  G
Sbjct: 893  EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952

Query: 302  KPGIKGDKGSPGPYGPKGPRGIQ---------------GITGPPGDPGPKGFQGNKGEPG 346
              G  G  G+PGP+GP GP G                 G  GP G  GP+G +G+KGEPG
Sbjct: 953  NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012

Query: 347  PPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG 404
              GP G PG  G  G QG+ G  G  G  GAPG +G  G  G  GP GP G  G  G PG
Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072

Query: 405  E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIG 452
              G  G +G +G +GP GP               GP GP GP G+ G G
Sbjct: 1073 TVGPAGIRGPQGHQGPAGPP--------------GPPGPPGPPGVSGGG 1107



 Score = 31.2 bits (69), Expect = 5.8
 Identities = 14/41 (34%), Positives = 19/41 (46%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP 284
            +G  G PGPPG  G PG+ G     G  G+  + +     P
Sbjct: 1086 QGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAP 1126


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  422 bits (1084), Expect = e-117
 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            EKGD G PGPPG  G  G +G  GP G PG+      G RG  G PG KG KGERG  GK
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 303  --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344
                          PG+ G  G PGP G     KGP G  G+ G  G PG  G  G KGE
Sbjct: 412  DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471

Query: 345  PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391
            PG         PGP G PG PG+ G +GI G +G    +G PG+PG  G+ G PG PG +
Sbjct: 472  PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531

Query: 392  GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433
            G  G+ GE+G          +PG+    G PG KG  G  G  G +GL G    L++ GE
Sbjct: 532  GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591

Query: 434  KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484
            KGD GP G         P GP G PG G QGE G+QG  G PG  GP G+   G +GE+ 
Sbjct: 592  KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649

Query: 485  QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528
                  GP GP GP G  G QGP G PGS+G  G PG+PG D           G  G KG
Sbjct: 650  VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709

Query: 529  EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579
            + G PG +G  G PGK G+PG  G  G  G+K        G  G  G PG  G  GE G 
Sbjct: 710  DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769

Query: 580  MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623
            +G  G+PG  +PG P      GP+GD G PG PG +G PG  I GP+G Q          
Sbjct: 770  IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827

Query: 624  --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675
                    GP+G  G PGL   G+PG  G  G+PG  G MG   +G  G  G PG+ GPP
Sbjct: 828  QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885

Query: 676  GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724
            G  G       P  +G  GP G+ G  G  G PG PG     G+ G KGEQG +G PGP 
Sbjct: 886  GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944

Query: 725  GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774
              + H + G KGE G +G  G  G+KG  G PG PG +GL+         GP+GDLG T
Sbjct: 945  SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002



 Score =  418 bits (1075), Expect = e-116
 Identities = 273/629 (43%), Positives = 319/629 (50%), Gaps = 110/629 (17%)

Query: 244  KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295
            +GDPG PGPPG  G PG  I+G RG +G PG      Q+G  G+ GP G PG  G    G
Sbjct: 791  RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355
              GE G PGI G +G  GP G +G  G  GI GPPG+ G  G  G  G  GPPGP G+PG
Sbjct: 851  FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910

Query: 356  APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389
             PG  G  GI G +GQ G PGA         PGP  +                G PG+ G
Sbjct: 911  TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970

Query: 390  PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435
             RG  G+PG +GL G     G PGP+G+ GS G  G  GL+G+            KG++G
Sbjct: 971  NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030

Query: 436  DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491
             +G  G  G  G+PGI G QG++G  G      PGP GP G  GLPG  G+ G+MG  GP
Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090

Query: 492  RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP 549
             G +G  G +G  G PGS GLPG+PG  G+ G  G KG  G PG RGP G PG  G PGP
Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150

Query: 550  KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM-GPFGMPGTSIPGPPGPKGDRGGPGIPGF 608
             G       +G+QG+ G+PGP G KGE G++  P G  G   PG  G KGDRG PG PG 
Sbjct: 1151 MG------IRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN--PGAQGAKGDRGAPGFPGL 1202

Query: 609  KGEPGL----SIRGPKGVQGPRGPVGAPG--LKGD-GYPGVPGPRGLPGPPGPMGLRGVG 661
             G  G       RGP G++G  GP G PG  + G  G  G PG RG PG PGP G  G  
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262

Query: 662  DTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGP---PGY-GSQGIKGEQG 716
              G KG+ G  G PGP GP G  G  GP G  G  G PG PGP   PG+ G  G+KGE+G
Sbjct: 1263 VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322

Query: 717  PQGF---------------------------------PGPKGTMGHGLPGQKGEHGERGD 743
              GF                                 PGP GT G   PG +GE G  G 
Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE--PGMQGEPGPPGP 1380

Query: 744  VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G  G  G  G+PG  GK G  GP G+ G
Sbjct: 1381 PGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409



 Score =  411 bits (1057), Expect = e-114
 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%)

Query: 240  CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293
            C  + G+PG PG PG    PG KGE      G  G PG   ++G +GE G  G+PG  G 
Sbjct: 722  CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 294  KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351
             G  G  G  G +GD G PGP G +GP G  I+G  G  G PG  G +G +G  G  GP 
Sbjct: 779  PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838

Query: 352  GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404
            G PG PG+ + G  GE G  G PG  G +G        G PG  GP G +GV G  G PG
Sbjct: 839  GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898

Query: 405  E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456
              G PGP G  G+ G  G  G+ G  +KG++G  G  G QG  G PG       IG +GE
Sbjct: 899  AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956

Query: 457  QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514
             G++G  G PG +G  G  G+PG KG  G  GP GP GP G +G  G  GEPG  G+PG 
Sbjct: 957  PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016

Query: 515  PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556
             G  G  G+ GK+G  G PG  G  G PG                   G PGP GD G  
Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076

Query: 557  GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600
            G  G +G+ G PGP G  G  G  G  G PG+  +PG PGP GD               R
Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136

Query: 601  GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648
            G PG+PGF G PG + IRG +G  G  GP G           PG +G+ G  G  G RG 
Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196

Query: 649  PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701
            PG PG  G +G +GD G +G  G+ G PGP G      P   G +GP G  G  G PGPP
Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 702  GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751
            GPPG    GIKG++G  G PGPKG  G           G PG  G  G RGD G +G  G
Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 752  EIGEPGSPGKQGLQGPKGDLG 772
              GE G+PG  G  GP G +G
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337



 Score =  397 bits (1021), Expect = e-110
 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287
           C   KG+ G PG PGT G PGI G  G KG  G   K            G  G  GP G+
Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184

Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333
           PG  G  G  G  G PG  G  G+ GP GP           KG RG++G+TGPPG P   
Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244

Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371
                         G KG +G  GEPGPPGP G P        GAP  G  G++G+ G++
Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302

Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411
           G PG PG  GV G  G PG  G +G+ G++G  G                   EG PGP 
Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362

Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452
           G +G+ GP GP G  G+                   +KG KG+ G  G +  MG PG  G
Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421

Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498
             G  G+ G  GPPGP G        P   GLPG  G  G  G  GP+G  G+       
Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481

Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558
           + GP G PG  GL G  G+PG  GAAG KG  G PG  G  G P  G PG +GD G KG 
Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539

Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613
           KG     +GQ G+PG  G +G+PG  G  G+PGT  + G PGPKG+    G  G +G PG
Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668
               G  G  GP GP G PG    G PG+ G +G+PG PGP G  G        T   G 
Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657

Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724
           PG  GPPG  GP+G  G  G  G  G  GLPGP   PG PG G  G  G +G QGFPG K
Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717

Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755
           G++G              GLPG KGE         G  G  G++G+ GE GE        
Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777

Query: 756 -PGSPGKQGLQGPKGDLG 772
            PG+PG +GL GP+GD G
Sbjct: 778 LPGTPGNEGLDGPRGDPG 795



 Score =  390 bits (1002), Expect = e-108
 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%)

Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299
           C+  KG+ G+ G PG  G+PG KG  GP+G P     G  G +G  G+PG  G KG RG 
Sbjct: 41  CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95

Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358
            G PG  G  G PG  G  GP G+ G+      PG  G +G +G PG PG  G PG PG 
Sbjct: 96  SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149

Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406
            G +G KG            +G  G PGAPGP G+ G PG PGP GP G PG  G PG  
Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209

Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439
            P            G KGE+G +G TGP G  G  I               KG+KG +G 
Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457
            GP GP G+PG                                          +G  G +
Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329

Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498
           G +G IGPPG +GP            +G PG  G  G  GP GP GP G+         G
Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389

Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551
           ++G  G PG  G  G+ G PG+D     G+ G  G  GLPG+ GP GPPG    + GP G
Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449

Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587
           D G  G  G+    G+PG +GPKGEPG++        GP G+PG                
Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506

Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636
                 PG PG  G  G PG PG +G+PG        L   G  GV G  G  G PG KG
Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566

Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694
            DG PG PG +GLPGP G + L G  GD G  G+PG  G PGP+GP G    GP+G+ G 
Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626

Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719
           +G                             PGPPGPPG+       G  G  G+ G  G
Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686

Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770
            PGP G  G       G PG KG+ G  G  G  G  G++GEPG PGK GL G KG+
Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743



 Score =  390 bits (1001), Expect = e-108
 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%)

Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299
           +KG  G+PGPPG  G PG     E+G  G+PG   +G+ G+ G  G PG +G KG RG  
Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320

Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348
              G+ GIKG KG  GP G +GP         +G +G  GPPG  G +G QG  G PG P
Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380

Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399
           G  GS  PG  G  G  G+KG +G+ GRP     G PG  G  G PG PG  GP G PG+
Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440

Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448
               +G PG+ G PG  G  G  G  GP+G  GL       I G  G  G  G  G  GI
Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500

Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502
           P  G QG  G++G  G PG  G P   G PG++G+ G  G  G    P G VG+ G  G 
Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558

Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553
           +G+PG  GL G PG PG  G  G KGE  L G +G +GPPG     G PGP G       
Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618

Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613
           G +G  G QG +G+PG  GP GE G  G   +  T +PGPPGP G  G PG  G  G PG
Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677

Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660
               G  G  G  GP G PG+ G G+PG PGP+G  G PG  G  G              
Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735

Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719
           G  GAKGEP V  P GP  P   G +G  G+ G+ GLPG PG PG  G++G+ G +G  G
Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795

Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753
            PGP G  G                GL G KG+ G RG  G KGD            GE 
Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 754 GEPGSPGKQGLQGPKGDLG 772
           G PG PG QG  GP G  G
Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874



 Score =  390 bits (1001), Expect = e-108
 Identities = 246/531 (46%), Positives = 281/531 (52%), Gaps = 87/531 (16%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298
            ++G PG PG  G  G PG KGE+G KGNPG ++     G+ GE G  G  G  G+KG RG
Sbjct: 914  QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973

Query: 299  ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347
              G PG+KG KG PGP GP GPRG  G TG PG+PG +G     GN G PG         
Sbjct: 974  VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033

Query: 348  -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403
             PG  G PG PGI G QG KGE G  EG RPG PGP   G+PG PG  G +G  G+ G P
Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091

Query: 404  G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451
            G       EG PG  G  G  G  GP G   L  KG KG +GP G +GP G+PG      
Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149

Query: 452  -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486
                 G QG  GI GP G          PPGP+G  G           G PG  G  G M
Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209

Query: 487  GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545
            G  GPRGP GI G  GP G PG+I       +PG+ G  G  G  G PGA GP GPPG  
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262

Query: 546  QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605
              G KGD   KGS G+ G +G PG  G  G PG +G  G PG  +PGP G  G +G PG+
Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317

Query: 606  PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665
             G KG PG    G  G  GP GP G PG++GD  PG      LPG PGP         G 
Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365

Query: 666  KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGE 714
             GEPG++G PGP GP G +G  GP+G  G+ G PG PGP G  G++G KGE
Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416



 Score =  301 bits (772), Expect = 2e-81
 Identities = 186/405 (45%), Positives = 214/405 (52%), Gaps = 30/405 (7%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302
            ++G  G PG  G  G PGI G +G KG PG ++    G  GP G PG  GD G++GE G+
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ 1087

Query: 303  PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQ 361
            PG  G  G  GP G  G  G  G+ G PG  G  GF+G KG  GPPG  G PG PG  G 
Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147

Query: 362  QGIKGERGQEGRPGAPGPIG-VGEPG----QPGPR---GPEGVPGERGLPG-EGFPGPKG 412
             G  G RG +GR G PGP G  GE G     PGPR   G +G  G+RG PG  G PG KG
Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKG 1207

Query: 413  EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGP 471
              G  GP GP G++G          GP G  G + IPG  G++G  G +G  G PGP GP
Sbjct: 1208 AMGDAGPRGPTGIEGFP--------GPPGLPGAI-IPGQTGNRGPPGSRGSPGAPGPPGP 1258

Query: 472  AGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527
             G  + G KG+ G MG  GP+GP G    +G  G  G PG+ GLPG  G PG  G  G K
Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318

Query: 528  GEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587
            GE G PG  G  GPP  G  GPKG  G +G  G      LPG  GP G PG  G  G PG
Sbjct: 1319 GEKGNPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376

Query: 588  TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632
               PGPPG  G  G  G PG  G+PG    GP G +G +G  G P
Sbjct: 1377 P--PGPPGNLGPCGPRGKPGKDGKPGTP--GPAGEKGNKGSKGEP 1417



 Score =  214 bits (544), Expect = 5e-55
 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%)

Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560
           G KGE G  G PG PG PG+ G  G +G   LPG +GP     KG PG  G  G KG +G
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94

Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620
             G  G  G  G  G PG  GP+G+ G  +PG  G KG++G PG+PG  G PG+      
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147

Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670
           G  G +G  GAP          KGD G PG PGP+GLPGPPG  G  G  G  G  G PG
Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207

Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718
             GP GP G  G    G KG+ G KGL GPPGPPG               +G KG++G  
Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267

Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776
           G PGP G  G  LPG+    E G  GD G +G  G+ G PG PG +G++G +G  GL  E
Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 777 EIIK 780
           + IK
Sbjct: 326 DGIK 329



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788
           G  G+KGE G  G  G  G KG  G  G PG QG +G  G  GLT  + ++ I+ + G  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814
                 G      P  LV V   S S G + F
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  420 bits (1079), Expect = e-117
 Identities = 276/688 (40%), Positives = 326/688 (47%), Gaps = 167/688 (24%)

Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGD---KG 295
           +KG  G+PG  G HG PG  G++G +G  G+     +KGE GE+G   + G  G+   KG
Sbjct: 305 QKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKG 364

Query: 296 ERGECGKPGIKGDKGSPGPYGPK---GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
           + G  G PG KG+KG  GP GP    G  GIQG  GPPG  G +G +G  G PG PGP G
Sbjct: 365 DLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG 424

Query: 353 SPGAPGI---------------------GQQGIKGERGQEGRPGAPGPIG----VGEPGQ 387
            PG PGI                        G+KG++G+ G PG PG +G     GEPG+
Sbjct: 425 PPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE 484

Query: 388 P------GPRGPEGVPGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQG---- 427
           P      G RG  GV G +G+ GE          G PG KG++GS G  GP+G  G    
Sbjct: 485 PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544

Query: 428 ---------LSIKGEKGD----IGP---VGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGP 471
                      IKGEKGD    IGP    GP+G  G PG    GE G+ G  G PGP+GP
Sbjct: 545 PGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604

Query: 472 AGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP------GSIGLPGQPGVPGEDGAA 524
            G+ GLPG  G  G +GP G   P   G QGP GEP      G  GLPG PG PG DG  
Sbjct: 605 KGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVP 664

Query: 525 GKKGEAGLP-------------------------------------GARGPEGPPGK--- 544
           G+ G+ GLP                                     G  G  G PGK   
Sbjct: 665 GRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDS 724

Query: 545 -------GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGP 596
                  G  GP G  G++G KG++G+RG PG  G KG+ G+ G  G+PG   P GPPG 
Sbjct: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784

Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP---------------GLKGDGYPG 641
            G  G PG  G KGE G    GP G  GP GP G P               G+    YPG
Sbjct: 785 MGRTGHPGPTGAKGEKGSD--GPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842

Query: 642 VPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPP 701
            PGP G  G PGP     VG+ GA G PG+ G PG  G R  G  GP G  G  G PG P
Sbjct: 843 PPGPPGPKGDPGP-----VGEPGAMGLPGLEGFPGVKGDR--GPAGPPGIAGMSGKPGAP 895

Query: 702 GPPGY-GSQGIKGEQGPQGFPGPKGTMGH----------------GLPGQKGEHGERGDV 744
           GPPG  G  G +G  G  GFPGP+G  G                 G PG +G  GERGD 
Sbjct: 896 GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ 955

Query: 745 GKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
           G  GD+G  GE G PG  G++G  G +G
Sbjct: 956 GIPGDRGSQGERGKPGLTGMKGAIGPMG 983



 Score =  402 bits (1032), Expect = e-111
 Identities = 265/627 (42%), Positives = 317/627 (50%), Gaps = 104/627 (16%)

Query: 245  GDPGDPGPPGTHGNPGIKG---------ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKG 295
            G PG PGPPG  G PGI+G          +  KGN  +   G  G++G  G+PG+ G  G
Sbjct: 415  GPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVG 474

Query: 296  ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP---------KGFQGNKGEPG 346
             +G+ G+PG    KG  G  G  G  G QG+ G PGDPGP         KG QG+ G  G
Sbjct: 475  PKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534

Query: 347  PPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEG 406
            P GP G  G P  G+ GI G++G +G  G PG I +G PG PGP+G  G PG + LPGE 
Sbjct: 535  PRGPPGDVGLP--GEHGIPGKQGIKGEKGDPGGI-IGPPGLPGPKGEAGPPG-KSLPGE- 589

Query: 407  FPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQG 461
             PG  G  G+ GP GP+G +GL  + G  GDIGP G    +GIPG     G  GE GIQG
Sbjct: 590  -PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG----IGIPGRTGAQGPAGEPGIQG 644

Query: 462  PIGPPG----PQGPAGQGLPGSKGEVGQMGPTGP------RGPVGI-------------- 497
            P G PG    P  P   G+PG  G+ G  GP G        G +G               
Sbjct: 645  PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVP 704

Query: 498  ------GVQGPKGEP---------GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPP 542
                  G +G  GEP         G IG  G PG+PG +G  G KGE G PG  G +G  
Sbjct: 705  GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDE 764

Query: 543  G-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPG-PKGDR 600
            G +G PG  G  G  G  G  G+ G PGP G KGE G  GP G PG   PGPPG P  +R
Sbjct: 765  GLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP--PGPPGIPFNER 822

Query: 601  ----------GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLP 649
                      GG  +P + G PG    GPKG  GP G  GA GL G +G+PGV G RG  
Sbjct: 823  NGMSSLYKIKGGVNVPSYPGPPGPP--GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPA 880

Query: 650  GPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-- 706
            GPPG  G+   G  GA G PGV G PG  GP G +G  GP+G +G+ G+ G  G PG   
Sbjct: 881  GPPGIAGMS--GKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938

Query: 707  -----GSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPG 757
                 G +G KGE+G QG PG +G+ G     GL G KG  G  G  G KG  G  G  G
Sbjct: 939  IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998

Query: 758  SPGKQGLQGPKGDLGLTKEEIIKLITE 784
             PG  G+ G   D  ++ EEI K I +
Sbjct: 999  PPGSPGIPGIPAD-AVSFEEIKKYINQ 1024



 Score =  375 bits (962), Expect = e-103
 Identities = 262/652 (40%), Positives = 307/652 (47%), Gaps = 149/652 (22%)

Query: 244  KGDPGDPGPPGTHGNPGIKGERG------PKGNPGNA----------QKGEAGERG-PGG 286
            KG+PGDPGPPG  G+PG+KG++G      P+G PG+           ++G  GE+G PGG
Sbjct: 506  KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGG 565

Query: 287  I---PGYKGDKGERGECGK-----PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338
            I   PG  G KGE G  GK     PG+ G+ G+PGP GPKG RG+ G+ G PGD GP+G 
Sbjct: 566  IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI 625

Query: 339  --------QGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-------- 381
                    QG  GEPG  GP G PG PG  G  G  G  G++G+PG PGP G        
Sbjct: 626  GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLL 685

Query: 382  ------------------------------VGEPGQP---------GPRGPEGVPGERGL 402
                                           GEPG+          GPRGP G+PG  G 
Sbjct: 686  GDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGP 745

Query: 403  PGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQ 457
             G     G+PG  GEKG EG  G  G     I G  G  GP G  G  G PG  G++GE+
Sbjct: 746  KGSKGERGYPGIPGEKGDEGLQGIPG-----IPGAPGPTGPPGLMGRTGHPGPTGAKGEK 800

Query: 458  GIQGPIGPPGPQGPAG---------QGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507
            G  GP G PGP GP G           L   KG V      GP GP G  G  GP GEPG
Sbjct: 801  GSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPG 860

Query: 508  SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGL 567
            ++GLPG  G PG     G +G AG PG  G  G PG   PGP G  G+ G +G  G  G 
Sbjct: 861  AMGLPGLEGFPG---VKGDRGPAGPPGIAGMSGKPGA--PGPPGVPGEPGERGPVGDIGF 915

Query: 568  PGPEGPKGEPGIMGPFGMPGTS----IPGPPGPKGDRGGPGIPGFKGEPGLSIR-GPKGV 622
            PGPEGP G+PGI G  G+PG       PG  GPKG+RG  GIPG +G  G   + G  G+
Sbjct: 916  PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGM 975

Query: 623  QGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG----------------LRGVGDTGA 665
            +G  GP+G PG KG  G PG  GP G PG PG                   LR   +  A
Sbjct: 976  KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035

Query: 666  KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725
                 ++ P      +  G  GP G  G  G PG PGP GY  +G KGE+G  G      
Sbjct: 1036 VFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGY--RGQKGERGEPGI----- 1088

Query: 726  TMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777
                GLPG  G  G             +G PGSPG  G QGP G  G    E
Sbjct: 1089 ----GLPGSPGLPG----------TSALGLPGSPGAPGPQGPPGPSGRCNPE 1126



 Score =  357 bits (915), Expect = 5e-98
 Identities = 246/657 (37%), Positives = 305/657 (46%), Gaps = 182/657 (27%)

Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352
           +KGE G  G PG  G KG     G  G  G+ G  G PG  G +GF+G+KGE G  G  G
Sbjct: 290 NKGEAGLPGAPGSPGQKGHK---GEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG 346

Query: 353 SPGAPGI----GQQGIKGERGQEGRPGAPGPIG-VGEPGQP------GPRGPEGVPGERG 401
             G P +    G+ G+KG+ G  G PG  G  G  G PG P      G +GP+G PG+ G
Sbjct: 347 EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEG 406

Query: 402 LPG-EGFPGPKGEKGSEGPTGPQGLQGL---------------------SIKGEKGDI-- 437
             G  G  GP G+ G  GP GP G+QG+                      +KG+KG+   
Sbjct: 407 QRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL 466

Query: 438 ----GPVGPQGPMGIPGIG-SQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR 492
               G VGP+G  G PG   ++GE+G +G  G  G QG  G+  PG  G  G +G  G +
Sbjct: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE--PGDPGPPGLIGSPGLK 524

Query: 493 GPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE-------AGLPGARGPEGPPGK 544
           G  G  G  GP+G PG +GLPG+ G+PG+ G  G+KG+        GLPG +G  GPPGK
Sbjct: 525 GQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK 584

Query: 545 ---GQPGPKGDEGKKGSKGNQGQRGLP--------------------GPEGPKGEPGIMG 581
              G+PG  G+ G  G +G +G+RGLP                    G +GP GEPGI G
Sbjct: 585 SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQG 644

Query: 582 PFGMPG-------------------TSIPGPPGP-------------------------- 596
           P G+PG                     +PGPPG                           
Sbjct: 645 PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVP 704

Query: 597 -----KGDRGGPGIPGF------------KGEPGLSIR-GPKGVQGPRGPVGAPGLKGD- 637
                KG+ GG G PG             +G PG+  R GPKG +G RG  G PG KGD 
Sbjct: 705 GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDE 764

Query: 638 GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGP---PGPSGPRGV------- 683
           G  G+PG  G PGP GP GL G     G TGAKGE G  GP   PGP GP G+       
Sbjct: 765 GLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNG 824

Query: 684 --------------------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPG 722
                               G  GPKGD G  G PG  G PG  G  G+KG++GP G PG
Sbjct: 825 MSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPG 884

Query: 723 PKGTMGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
             G  G        G+PG+ GE G  GD+G  G +G  G+PG  GK G+ G +G +G
Sbjct: 885 IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941



 Score =  296 bits (758), Expect = 7e-80
 Identities = 205/521 (39%), Positives = 251/521 (48%), Gaps = 110/521 (21%)

Query: 324 QGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV- 382
           +G  G PG PG  G +G+KGEPG  G +   GAP     G  G++G++G  G+ G  G  
Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLH---GAP-----GFPGQKGEQGFEGSKGETGEK 342

Query: 383 GEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIG 438
           GE G+ G     G+ GE GL G+    G PGPKGEKG  GP GP  L         G +G
Sbjct: 343 GEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP--------GSLG 394

Query: 439 PVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG 496
             GPQGP G  G  G +G+ G  G  GPPGP GP G QG+  + G        G      
Sbjct: 395 IQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA 454

Query: 497 IGVQGPKGE------PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGP 549
            G++G KGE      PGS+G  GQ G PGE    G+KG+ G PG  G +G  G+ G PGP
Sbjct: 455 GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP 514

Query: 550 KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFK 609
            G  G  G KG QG  G  GP GP G+ G+ G  G+PG                GI G K
Sbjct: 515 PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQ--------------GIKGEK 560

Query: 610 GEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEP 669
           G+PG  I GP G+ GP+G  G PG    G PG+ G  G PGP GP G RG+        P
Sbjct: 561 GDPG-GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGL--------P 611

Query: 670 GVRGPPGPSGPRGVG------TQGPKGDTG---QKGLPGPPGPPGY-GSQGIKGEQGPQG 719
           GV G PG  GP+G+G       QGP G+ G    +GLPG PG PG  G+ G+ G  G  G
Sbjct: 612 GVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG 671

Query: 720 FPGPKGT------MGH-----------------GLPGQKGEHG------------ERGDV 744
            PGP G       +G                  GL   KGE G             +GD+
Sbjct: 672 LPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDI 731

Query: 745 GK------------KGDKGEIGEPGSPGKQGLQGPKGDLGL 773
           G             KG KGE G PG PG++G +G +G  G+
Sbjct: 732 GPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGI 772



 Score =  199 bits (507), Expect = 9e-51
 Identities = 130/314 (41%), Positives = 164/314 (52%), Gaps = 60/314 (19%)

Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGA------RGPEGPPGK-------GQPGPKGDEGKKG 557
           LP +  +  +      KGEAGLPGA      +G +G PG+       G PG KG++G +G
Sbjct: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334

Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSI 616
           SKG  G++G  G +G     G+ G  G+ G   P GPPGPKG++G  G PG    P    
Sbjct: 335 SKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP---- 390

Query: 617 RGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGVGDT------------ 663
            G  G+QGP+GP G  G +G  G  G PG  G PGPPGP G++G+  T            
Sbjct: 391 -GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGN 449

Query: 664 ---------GAKGEPGVRGPPGPSGPRGVG-------TQGPKGDTGQ---------KGLP 698
                    G KGE G+ G PG  GP+G         T+G KGD G+         KG P
Sbjct: 450 DEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEP 509

Query: 699 GPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGE-IGE 755
           G PGPPG  GS G+KG+QG  G  GP+G  G  GLPG+ G  G++G  G+KGD G  IG 
Sbjct: 510 GDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGP 569

Query: 756 PGSPGKQGLQGPKG 769
           PG PG +G  GP G
Sbjct: 570 PGLPGPKGEAGPPG 583



 Score =  172 bits (436), Expect = 2e-42
 Identities = 113/284 (39%), Positives = 134/284 (47%), Gaps = 61/284 (21%)

Query: 542 PGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDR 600
           P KG+ G  G  G  G KG++G+ G  G  G  G PG  G  G  G+    G  G +G++
Sbjct: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348

Query: 601 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLPGPPGPMG 656
           G P + G  GE GL     KG  GP GP G  G KGD    G P +PG  G+ GP GP G
Sbjct: 349 GDPALAGLNGENGL-----KGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403

Query: 657 LRGV----GDTGAKGEPGVRGPPGPSGPRGV---------------------GTQGPKGD 691
             G     G TG  G+PG  GPPGP G +G+                     G +G KG+
Sbjct: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463

Query: 692 TGQKGLPGPPGPPG----------------------YGSQGIKGEQGPQGFPGPKGTMGH 729
           TG  G PG  GP G                       GSQG+KGE G    PGP G +G 
Sbjct: 464 TGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD---PGPPGLIGS 520

Query: 730 -GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772
            GL GQ+G  G  G  G  GD G  GE G PGKQG++G KGD G
Sbjct: 521 PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564



 Score = 99.4 bits (246), Expect = 2e-20
 Identities = 65/186 (34%), Positives = 80/186 (43%), Gaps = 45/186 (24%)

Query: 243  EKGDPGDPGPPGTHGNPGIKGERG------PKGNPGN-AQKGEAGERGPGGIPGYKGDKG 295
            ++G PGD G  G  G PG+ G +G      P GN G+    G  G  G  GIPG   D  
Sbjct: 954  DQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAV 1013

Query: 296  ERGECGK--------------------PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP 335
               E  K                      +     +   YG  GP G  G+ GPPGDPGP
Sbjct: 1014 SFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGP 1073

Query: 336  KGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEG 395
            +G++G KGE G PG  G PG+PG+                 PG   +G PG PG  GP+G
Sbjct: 1074 QGYRGQKGERGEPG-IGLPGSPGL-----------------PGTSALGLPGSPGAPGPQG 1115

Query: 396  VPGERG 401
             PG  G
Sbjct: 1116 PPGPSG 1121



 Score = 33.1 bits (74), Expect = 1.5
 Identities = 17/47 (36%), Positives = 26/47 (55%)

Query: 727 MGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773
           M   LP ++    +   +  KG+ G  G PGSPG++G +G  G+ GL
Sbjct: 271 MSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGL 317


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.140    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,138,487
Number of Sequences: 37866
Number of extensions: 5215341
Number of successful extensions: 253335
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 484
Number of HSP's successfully gapped in prelim test: 1299
Number of HSP's that attempted gapping in prelim test: 18213
Number of HSP's gapped (non-prelim): 16350
length of query: 1125
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1012
effective length of database: 13,968,660
effective search space: 14136283920
effective search space used: 14136283920
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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