BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|154759255 collagen, type XXVIII precursor [Homo sapiens] (1125 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 2345 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 463 e-130 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 460 e-129 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 459 e-129 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 452 e-126 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 448 e-125 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 447 e-125 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 447 e-125 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 447 e-125 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 446 e-125 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 446 e-125 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 446 e-125 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 442 e-124 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 442 e-124 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 442 e-124 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 441 e-123 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 441 e-123 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 441 e-123 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 435 e-121 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 434 e-121 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 433 e-121 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 431 e-120 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 431 e-120 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 431 e-120 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 431 e-120 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 430 e-120 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 426 e-119 gi|48762934 alpha 2 type I collagen [Homo sapiens] 424 e-118 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 422 e-117 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 420 e-117 >gi|154759255 collagen, type XXVIII precursor [Homo sapiens] Length = 1125 Score = 2345 bits (6078), Expect = 0.0 Identities = 1125/1125 (100%), Positives = 1125/1125 (100%) Query: 1 MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK 60 MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK Sbjct: 1 MWNRYFVFYLLLLSAFTSQTVSGQRKKGPKSNLLARKSDVQGSICFIDIVFIVDSSESSK 60 Query: 61 IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK 120 IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK Sbjct: 61 IALFDKQKDFVDSLSDKIFQLTPGRSLEYDIKLAALQFSSSVQIDPPFSSWKDLQTFKQK 120 Query: 121 VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI 180 VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI Sbjct: 121 VKSMNLIGQGTFSYYAISNATRLLKREGRKDGVKVVLLMTDGIDHPKNPDVQSISEDARI 180 Query: 181 SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC 240 SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC Sbjct: 181 SGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDKIQDRLDILFEKKCERKIC 240 Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC Sbjct: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG Sbjct: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360 Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT Sbjct: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK 480 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK Sbjct: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSK 480 Query: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG Sbjct: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 Query: 541 PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR 600 PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR Sbjct: 541 PPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDR 600 Query: 601 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV Sbjct: 601 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF Sbjct: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720 Query: 721 PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK Sbjct: 721 PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 Query: 781 LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII 840 LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII Sbjct: 781 LITEICGCGPKCKETPLELVFVIDSSESVGPENFQIIKNFVKTMADRVALDLATARIGII 840 Query: 841 NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL 900 NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL Sbjct: 841 NYSHKVEKVANLKQFSSKDDFKLAVDNMQYLGEGTYTATALQAANDMFEDARPGVKKVAL 900 Query: 901 VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY 960 VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY Sbjct: 901 VITDGQTDSRDKEKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDPEHVY 960 Query: 961 QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS 1020 QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS Sbjct: 961 QFDDFFTLQDTLKQKLFQKICEDFDSYLVQIFGSSSPQPGFGMSGEELSESTPEPQKEIS 1020 Query: 1021 ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN 1080 ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN Sbjct: 1021 ESLSVTRDQDEDDKAPEPTWADDLPATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGN 1080 Query: 1081 CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125 CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG Sbjct: 1081 CGEYVVRWYYDKQVNSCARFWFSGCNGSGNRFNSEKECQETCIQG 1125 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 463 bits (1192), Expect = e-130 Identities = 280/631 (44%), Positives = 323/631 (51%), Gaps = 109/631 (17%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGK 302 +G PG PGP G G G +GERGP+G G KG +G GP G PG +G G +G G Sbjct: 900 RGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGF 959 Query: 303 PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 PG KG G PG G +G G QG TGPPG PG G QG GE GP G G PG Sbjct: 960 PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGP 1019 Query: 357 PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----------E 405 PG G+QG+ G G+EG G PGP G+ PG+ GP G G PG+RGLPG E Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGL--PGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077 Query: 406 GFPGPKGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQ 460 G PGP G GS G GP G G + I G G GP GP G G PG G G G+Q Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 461 GPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPG 507 GP+G PGP GP G G GSKG+ G+ GP GP GP QGP G+PG Sbjct: 1138 GPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP-----QGPIGQPG 1192 Query: 508 SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRG 566 G G+PG G+ G G+KG+ G G GP GP G +G PGP G++G+ G G G G Sbjct: 1193 PSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPG 1252 Query: 567 LPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGD---RGGPGIPGFKGEPG-LSIRGPKG 621 PGP GP G PG GP G PG PG G KG+ G PG+PG G PG RG KG Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKG 1312 Query: 622 VQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPPGPMGLRG------------------ 659 GP G G PG KG DG G PGP G PG PGP G G Sbjct: 1313 ESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372 Query: 660 -------VGDTGAKGEPGVRGPPGPSGPRG----------VGTQGPKGDTGQ---KGLPG 699 G+ G G PG RGPPGP+GP G G +GP G TG +G PG Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPG 1432 Query: 700 PPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGD--------- 743 PGP G G QG+ G GP G PGP G G LPG KG+ G +G+ Sbjct: 1433 KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG--LPGLKGDSGPKGEKGHPGLIGL 1490 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 +G G++GE G+ G PG QG GPKG+ G+T Sbjct: 1491 IGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT 1521 Score = 456 bits (1174), Expect = e-128 Identities = 274/602 (45%), Positives = 325/602 (53%), Gaps = 87/602 (14%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-------NAQKGEAGERGPGGIPGYKGDKGER 297 G PG G G+ G G+ G+ GPKG+ G +KG G+ GP G PG GD GER Sbjct: 604 GKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGER 663 Query: 298 GECGKPGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G+ G+ G +G G PGP G P GP G G+TG G PGPKG G +GEPGPPG Sbjct: 664 GDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQ 723 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE----G 406 G+PGA QG+ G +G G PG GP+G G PG PG GP G PG+ G PGE G Sbjct: 724 GNPGA-----QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG 778 Query: 407 FPGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP 462 PGP+G G GP G +G G+ KGEKG+ G G +G MGI G +GE G GP Sbjct: 779 PPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIK--GDRGEIGPPGP 836 Query: 463 IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVP 518 G GP+GP G+G G G+ G +GP G +G +G+ G G +G GSIG PG PG Sbjct: 837 RGEDGPEGPKGRG--GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN 894 Query: 519 GEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQGQRGLPGPE 571 GE G G G+ G G RGP GP G+ G+PGPKG+ G G G G+RG GP+ Sbjct: 895 GEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQ 954 Query: 572 GPKGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDR 600 GP G PG GP G PG T PGPP GP G+R Sbjct: 955 GPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGER 1014 Query: 601 GGPGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLR 658 G PG PG GE GL + G +G +G GP G PG G G G PG RGLPGP G +GL+ Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074 Query: 659 G----VGDTGAKGEPGVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPGYGSQG 710 G G G G PG RGP G +GP G+ G QGP G G+KG PG GP G G Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGP--QGPAG 1132 Query: 711 IKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 G QGP G PGP G +G PG+ G+ GE G+ G+KG KG+ GE G PG G QGP G Sbjct: 1133 RDGLQGPVGLPGPAGPVGP--PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190 Query: 771 LG 772 G Sbjct: 1191 PG 1192 Score = 450 bits (1157), Expect = e-126 Identities = 279/649 (42%), Positives = 327/649 (50%), Gaps = 128/649 (19%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGD---KGERGE 299 EKG G PGP G G PG +G +G G G KG GE+G G PG+KGD KG+RGE Sbjct: 773 EKGGQGPPGPQGPIGYPGPRGVKGADGIRG--LKGTKGEKGEDGFPGFKGDMGIKGDRGE 830 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 G PG +G+ G GP G GP G G GPPG+ G G G G PG GP GS G PG Sbjct: 831 IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890 Query: 360 GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGP 419 G GE+G G PG PGP GQ GP GP G G RG+ G+ PGPKG G +GP Sbjct: 891 --PGANGEKGGRGTPGKPGP-----RGQRGPTGPRGERGPRGITGK--PGPKGNSGGDGP 941 Query: 420 TGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG- 473 GP G +G + +G G GP GP GP G G+ G +GE G QG GPPGP G G Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001 Query: 474 QGLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPG---------- 516 QG G G +G+ G GP GP G G +G KG+PG GLPG+ G Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGD 1061 Query: 517 --VPGEDGAAGKKGEAGLPGARGPEGPPGK-------------GQPGPKGDEGKKGSKGN 561 +PG GA G KG G PG GP G PG+ G+PGP+G G G KG Sbjct: 1062 RGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGA 1121 Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPG-LSIRGP 619 G++G P+GP G G+ GP G+PG + P GPPG GD+G G PG KG G +GP Sbjct: 1122 PGEKG---PQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGP 1178 Query: 620 KGVQGPRGPVGAPGLKG-DGYPGV------------PGPRGLPGPPGPMGLRGV----GD 662 G GP+GP+G PG G DG PG GPRG PGPPGP+GL+G+ G+ Sbjct: 1179 PGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGE 1238 Query: 663 TGAKGEPGVRGPPGPSGPRG----------------------VGTQGPKGDTGQKGLPGP 700 G G+ G GPPGP GPRG VG +G G+ G+ GLPG Sbjct: 1239 KGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298 Query: 701 PGPPG-YGSQGIKGEQGPQGF---PGPKGTMGH--------------------------- 729 GPPG G +G KGE GP G PGPKG G Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358 Query: 730 -GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 G PG KG+ GE G G G GE G G PGK+G GP G G E+ Sbjct: 1359 DGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407 Score = 424 bits (1091), Expect = e-118 Identities = 271/594 (45%), Positives = 311/594 (52%), Gaps = 70/594 (11%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP--------GNAQKGEAGE--------------- 281 GDPG+ GPPG G PG G GP G G G G Sbjct: 493 GDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQ 552 Query: 282 -----RGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336 RGP G G G G G G G+KG+ G GP+GPRG+QG GP G PG + Sbjct: 553 ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD---VGPQGPRGVQGPPGPAGKPGRR 609 Query: 337 GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEG 395 G G+ G G PG G G G G G+ GE+G G PG GP G PG G RG +G Sbjct: 610 GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP--PGPPGDDGERGDDG 667 Query: 396 VPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPG---- 450 G RGLPGE PGP+G G +GP GP G G++ + G+ G G VGPQG G PG Sbjct: 668 EVGPRGLPGE--PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725 Query: 451 IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGS 508 G+QG G QG IGPPG +GP G+ GLPG G G G G GP G G QGP G G Sbjct: 726 PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGP 785 Query: 509 IGLPGQPGVPGED------GAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKGS 558 IG PG GV G D G G+KGE G PG +G G G G PGP+G++G +G Sbjct: 786 IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGP 845 Query: 559 KGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG----L 614 KG G G PGP GP GE G +G G+PG PG GPKG G PG PG GE G Sbjct: 846 KGRGGPNGDPGPLGPPGEKGKLGVPGLPG--YPGRQGPKGSIGFPGFPGANGEKGGRGTP 903 Query: 615 SIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVR 672 GP+G +GP GP G G +G G PG G G GP GP G RG G G G PG + Sbjct: 904 GKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963 Query: 673 GPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGP---QGFPGPKGTM 727 GPPGP G G+ G G +G+TG +G GPPGPPG G QG GE GP +G PGP G Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPP 1023 Query: 728 G-HGLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGLTKEE 777 G GLPG G+ G +GD G G G+ G P G PG +GL GP G LGL E Sbjct: 1024 GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077 Score = 418 bits (1075), Expect = e-116 Identities = 269/604 (44%), Positives = 302/604 (50%), Gaps = 82/604 (13%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGE 299 E KGDPG G PG G PG++G G +G PG G G GP G PG G GERG Sbjct: 1035 EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGP 1094 Query: 300 CGKPGIKGDKGSPGPYGPKGP---RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G G G PGP GP GP +G G GP G G G QG G PGP GP G PG Sbjct: 1095 AGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGE 1154 Query: 357 PG----IGQQGIKGERGQEGRPGAPGPIGVGEP-GQPGPRGPEGVPGERGLPG-EGFPGP 410 G IG+ G KG +G +G G PGP G P GQPGP G +G PG RG G G G Sbjct: 1155 DGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGD 1214 Query: 411 KGEKGSEGPTGPQGLQGL----SIKGEKGDI------GPVGPQGPMGIPGI--------- 451 +G +G GP GP GLQGL KGE GD+ GP GP+GP G PG Sbjct: 1215 EGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGG 1274 Query: 452 -------------GSQGEQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGP 488 G GE G+ G GPPGP+G G+ G PG KG G GP Sbjct: 1275 IGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGP 1334 Query: 489 TGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQ 546 G GPVG G GP GEPG G G PG G+DG G+ G G G GP GPPGK G Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGP 1394 Query: 547 PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP 606 PGP G EG++G KG +G+ GL GP PG GP G G PG PGP G RG PG Sbjct: 1395 PGPAGPEGRQGEKGAKGEAGLEGP------PGKTGPIGPQGA--PGKPGPDGLRGIPGPV 1446 Query: 607 GFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGA 665 G +G PG GP G GP GP G PGLKGD GP+G G PG +GL G G+ G Sbjct: 1447 GEQGLPGSP--GPDGPPGPMGPPGLPGLKGDS-----GPKGEKGHPGLIGLIGPPGEQGE 1499 Query: 666 KGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGE 714 KG+ G+ GP G SGP+G G GP G G GLPGPPGP G G +G G Sbjct: 1500 KGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGH 1559 Query: 715 QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GP G PGP G + LP Q D + D G GE G++ G L Sbjct: 1560 PGPPGPPGPPGEVIQPLPIQASRTRRNIDASQLLDDGN-GENYVDYADGMEEIFGSLNSL 1618 Query: 775 KEEI 778 K EI Sbjct: 1619 KLEI 1622 Score = 51.6 bits (122), Expect = 4e-06 Identities = 42/161 (26%), Positives = 52/161 (32%), Gaps = 60/161 (37%) Query: 670 GVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKG---------------- 713 G P P+ P G G + P P PPG G+ ++G Sbjct: 360 GEENPDQPTDP-GAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYD 418 Query: 714 ----------EQGP----------QGFPGPKGTMGH-----------------------G 730 E GP +G GP+G G G Sbjct: 419 PYYDPTSSPSEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAG 478 Query: 731 LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 LPG G G G VG G++G G PG PG GL GP G + Sbjct: 479 LPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTM 519 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 460 bits (1183), Expect = e-129 Identities = 287/630 (45%), Positives = 336/630 (53%), Gaps = 104/630 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKP 303 G+ G GPPG+ G PG G RG KG GN +GE GE+G G PG+KGD G +G+ GKP Sbjct: 692 GEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK---GFQGNKGEPGPPGPYGSPGAPG-- 358 G G +G GP GPKG G G GPPG G K G G G PG PGP GS G PG Sbjct: 752 GAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL 811 Query: 359 --IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPR------GPEGVPGERGLP 403 IG++G G+ GQ G G GP G G GQPGP+ G G+PGE+GLP Sbjct: 812 GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871 Query: 404 G----EGFPGPK------------------GEKGSEGPTGPQGLQG-LSIKGEKGDIGPV 440 G GFPGPK GE G +G TGP G G L +G+ G++GP+ Sbjct: 872 GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931 Query: 441 GPQGPMGIPG-------IGSQGEQGIQGPIGPPGP---QGPAG-QGLPGSKGEVGQMGPT 489 G +GP G PG G +G +G +G +GPPGP +GPAG +G PG KG G GPT Sbjct: 932 GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991 Query: 490 ------GPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKK------------ 527 GP GPVG G +GP G G IGLPGQ G G G AGKK Sbjct: 992 GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPT 1051 Query: 528 GEAGLPGARGPEGPPGKGQP-GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586 G+ G+PG GP GPPG P G +GD+G G+ G++G +G G GP G+PGI GP G P Sbjct: 1052 GKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHP 1111 Query: 587 GTSIPGPPGPKGDRGGPGIPGFKGEPG----LSIRGPKGVQGPRGPVGAPGLKGD----G 638 G PG G +G RG PG+ G KG+ G + + GP G+QG GP G G GD G Sbjct: 1112 GP--PGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMG 1169 Query: 639 YPGVPGPRGLPGPPGPMGL----RGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693 G PGPRG GP G G GVG GA GE G RG G GP G G GPKGD G Sbjct: 1170 PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG 1229 Query: 694 QKGLPGP---PGPPGY----GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERG 742 +KG GP GPPG G G KG GP G PG G G G+ G GE G+ G Sbjct: 1230 EKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPG 1289 Query: 743 DVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 DVG G G GEPG+PG G +GP G +G Sbjct: 1290 DVGGPGPPGASGEPGAPGPPGKRGPSGHMG 1319 Score = 438 bits (1127), Expect = e-122 Identities = 271/605 (44%), Positives = 320/605 (52%), Gaps = 91/605 (15%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-------NAQKGEAGERGPGGIPGYKGDKGE 296 +G G PG PG G G +G+ GP G G + G GERGP G PG G++G Sbjct: 889 QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGP---PGDPGPKGFQGNKGEPGPPGPYGS 353 G G+ G KG+ G PGP G +GP G++G GP PGDPGP G +G+KG PGP G GS Sbjct: 949 PGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGS 1008 Query: 354 PGAPG-------------------IGQQGIKGERGQEGRPGA------PGPIG-VGEPGQ 387 PG G +G G KG RG+ G PG PGP+G +G PG Sbjct: 1009 PGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGA 1068 Query: 388 PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMG 447 GP G EG G+ G PG G KG+KG GP G G++G + G G G G QG G Sbjct: 1069 AGPSGEEGDKGDVGAPGH--KGSKGDKGDAGPPGQPGIRGPA--GHPGPPGADGAQGRRG 1124 Query: 448 IPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGE 505 PG+ G +G+ G++G +G GP P QGLPG GE G++G G GP G G +GP+G Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGP--PGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182 Query: 506 PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR 565 GS G PG PG G+ GA G+KGE G G GP G PG PGPKGD G+KG G G Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGI--PGPKGDIGEKGDSGPSGAA 1240 Query: 566 GLPGPEGPKGE------------PGIMGPFGMPGTS-IPGPPGPKGDRG---GPGIPGFK 609 G PG +GP GE PG +GP G PG S I G PG KGD G GPG PG Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGAS 1300 Query: 610 GEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG--------- 659 GEPG GP G +GP G +G G +G+ G G PGP G PG GPMG RG Sbjct: 1301 GEPGAP--GPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEG 1358 Query: 660 -------VGDTGAKGEPGVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPGY-G 707 VG+ G G PG GPPGP GP G+ G GPKG+ G GL G GPPG G Sbjct: 1359 LRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAG 1418 Query: 708 SQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGP 767 +G +G G QG PGPKG PG G G G G G G +G+ GS G G GP Sbjct: 1419 EKGDQGLPGVQGPPGPKGD-----PGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGP 1473 Query: 768 KGDLG 772 +GD G Sbjct: 1474 RGDTG 1478 Score = 432 bits (1112), Expect = e-121 Identities = 266/602 (44%), Positives = 323/602 (53%), Gaps = 74/602 (12%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 EKG GD G G G PG GERG +G PG G+AGE GP G+ G +G G G G Sbjct: 561 EKGQRGDFGHVGQPGPPGEDGERGAEGPPGPT--GQAGEPGPRGLLGPRGSPGPTGRPGV 618 Query: 303 PGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 GI G KG+ GP G GP G QG G G PGP+G G GE GPPG G PG PG Sbjct: 619 TGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGS 678 Query: 360 -------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE------- 405 G +G GE+G +G PG+ GP PG PGPRG +G G RGL GE Sbjct: 679 DGPLGHPGHEGPTGEKGAQGPPGSAGP-----PGYPGPRGVKGTSGNRGLQGEKGEKGED 733 Query: 406 GFPGPKGE---------------KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450 GFPG KG+ +G +GP GP+G G + GE+G G G +G +G+PG Sbjct: 734 GFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA--GEEGPPGSAGEKGKLGVPG 791 Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSI 509 + G G G +G IG PGP GP G+ G G+ GQ G G RGP G +G +G+PG+ Sbjct: 792 LPGYPGRPGPKGSIGFPGPLGPIGE--KGKSGKTGQPGLEGERGPPGS--RGERGQPGAT 847 Query: 510 GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLP 568 G PG G G+DGA G GE GLPG +GP G PG KG PG +G +G+ G G +G+ G Sbjct: 848 GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQ 907 Query: 569 GPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIR-GPKGVQGPRG 627 G GP G G++GP G G GP G +G G PG PG +G PGL R G KG GP G Sbjct: 908 GQTGPPGPAGVLGPQGKTGEV--GPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPG 965 Query: 628 PVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV 683 P+G G G G PGP+G PG PGP GL+G G GA G PG RGP GP+G G+ Sbjct: 966 PLGKEGPAG--LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023 Query: 684 ----GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGH-------GL 731 G++GP G G+KG G GPPG G GI G GP G PG G G G Sbjct: 1024 PGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGA 1083 Query: 732 PGQKGEHGERGDVGK------KGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEI 785 PG KG G++GD G +G G G PG+ G QG +GP G G ++ ++ + Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGV 1143 Query: 786 CG 787 G Sbjct: 1144 IG 1145 Score = 431 bits (1109), Expect = e-120 Identities = 269/601 (44%), Positives = 318/601 (52%), Gaps = 72/601 (11%) Query: 241 ECEKGDPG---DPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296 E E+G PG + G PG G PG KG+ G G PG +KG G +GP G PG KG G Sbjct: 829 EGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGH 888 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 +G+ G+PG G +G G G GP G G+ GP G G G G +G PGPPGP G G Sbjct: 889 QGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGL 948 Query: 357 PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414 PG+ G++G KGE G G G GP G+ G PGP+G G PG GL G+ G PGP G Sbjct: 949 PGLEGREGAKGELGPPGPLGKEGPAGLR--GFPGPKGGPGDPGPTGLKGDKGPPGPVGAN 1006 Query: 415 GSEGPTGPQG-LQGLSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQ 469 GS G GP G G+ + G+ G GPVGP G G G G G+ GI GP+GP GP Sbjct: 1007 GSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPP 1066 Query: 470 GPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 G AG G G KG+VG G G +G G GP G+PG G G PG PG DGA G++G Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDA--GPPGQPGIRGPAGHPGPPGADGAQGRRG 1124 Query: 529 EAGLPGARGPEG---------PPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPG 578 GL G +G +G PPG +G PGP G++G+ G G+ G G PGP GP+G G Sbjct: 1125 PPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTG 1184 Query: 579 IMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGL----SIRGPKGVQGPRGPVGAPG 633 G G+PG PG G KG+RG G PG G PG+ G KG GP G G PG Sbjct: 1185 SEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPG 1244 Query: 634 LKG----DGYPGVPGPRGLPG---PPGPMGLRGV----------------GDTGAKGEPG 670 KG DG G GP GLPG PPG G+ G+ G GA GEPG Sbjct: 1245 KKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPG 1304 Query: 671 VRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG----YGSQGIKGEQGPQGF---PG 722 GPPG GP G +G +G +G+ G KG PGP GPPG G++G G GP+G PG Sbjct: 1305 APGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPG 1364 Query: 723 PKGTMGH-GLPGQKGEHGE---------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 P G G G PGQ G G +GD G KG+KG IG G G G G KGD G Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQG 1424 Query: 773 L 773 L Sbjct: 1425 L 1425 Score = 421 bits (1082), Expect = e-117 Identities = 266/598 (44%), Positives = 312/598 (52%), Gaps = 88/598 (14%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G G PGP G G+PG+KGE G +G +GP G+ G G G G+ G+PG Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEG-----------PQGPRGLQGPHGPPGRVGKMGRPG 533 Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360 G +G PG GPKG RG G+ G PG+ G +G G+ G+PGPPG G GA G G Sbjct: 534 ADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG 593 Query: 361 QQGIKGERGQEGRPGAPGPIG----------------VGEPGQPGPRGPEGVPGERGLPG 404 Q G G RG G G+PGP G VG PG+PGP G +G G +GLPG Sbjct: 594 QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653 Query: 405 -EGFPGPKGEK------------GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450 +G G GEK GS+GP G G +G + GEKG GP G GP G PG Sbjct: 654 PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT--GEKGAQGPPGSAGPPGYPGP 711 Query: 451 ---------IGSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGPRGPVG- 496 G QGE+G +G G PG +G G QG PG+ G G+ GP GP+G G Sbjct: 712 RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771 Query: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGD 552 G +GP G G G G PG+PG G G KG G PG GP G GK GQPG +G+ Sbjct: 772 AGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGE 831 Query: 553 EGKKGSKGNQGQRGLPGPEGPKGE------PGIMGPFGMPG----TSIPGPPGPKGDRGG 602 G GS+G +GQ G G GPKG+ PGI G G+PG PGP GP G +G Sbjct: 832 RGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGK 891 Query: 603 PGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGDGYP-GVPGPRGLPGPPGPMGLRGV 660 G PG G+ G L +G G GP G +G G G+ P G GP G PGPPG GL G+ Sbjct: 892 DGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGL 951 Query: 661 -GDTGAKGEPGVRGPPGPSGPRGV-GTQGPK---GDTGQKGLPGPPGPPG-YGSQGIKGE 714 G GAKGE G GP G GP G+ G GPK GD G GL G GPPG G+ G GE Sbjct: 952 EGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGE 1011 Query: 715 QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 +GP G G G GLPGQ G G G GKKG +GE G PG GK G+ GP G LG Sbjct: 1012 RGPLGPAG-----GIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLG 1064 Score = 403 bits (1036), Expect = e-112 Identities = 275/659 (41%), Positives = 322/659 (48%), Gaps = 126/659 (19%) Query: 232 EKKCERKICECEKGDP--GDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPG 289 EK + + EKG G PG PG G G G GP G P G+ G GP G+PG Sbjct: 374 EKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFP-----GDPGPPGPAGLPG 428 Query: 290 YKGDKGERGE---------------------------------------CGKPGIKGDKG 310 G G RG G PG G G Sbjct: 429 IPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG 488 Query: 311 SPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI----GQQGIKG 366 PGP G G G++G G G GP+G QG G PG G G PGA G G G KG Sbjct: 489 RPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKG 548 Query: 367 ERGQEGRPGAPGPIG-------VGEPGQP---GPRGPEGVPGERGLPGEGFPGPK---GE 413 +RG +G PG PG G VG+PG P G RG EG PG G GE PGP+ G Sbjct: 549 DRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGE--PGPRGLLGP 606 Query: 414 KGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGP 471 +GS GPTG G+ G+ G KG++GP G GP G G GSQG G QG IG PG +GP Sbjct: 607 RGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666 Query: 472 AGQ----GLPGS------------KGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQ 514 G GLPGS GE G GP G GP G G +G KG G+ GL G+ Sbjct: 667 PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGE 726 Query: 515 PGVPGEDGAAGKKGEAGL---------PGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQ 564 G GEDG G KG+ GL PG RG +GP G KGQ G G+EG GS G +G+ Sbjct: 727 KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGK 786 Query: 565 RGLPGPEGPKGEPGIMGPFGMPGTSIP----------GPPGPKGDRGGPGIPGFKGEPGL 614 G+PG G G PG G G PG P G PG +G+RG PG G +G+PG Sbjct: 787 LGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846 Query: 615 SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEP 669 + G G +G G GAPG+ G+ G PG+ GP G PGP GP G +G G G +GE Sbjct: 847 T--GQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGEL 904 Query: 670 GVRGPPGPSGPRGV----GTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGEQGPQ 718 G +G GP GP GV G G G G++G PGPPGPPG G +G KGE GP Sbjct: 905 GFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPP 964 Query: 719 GFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK---GEIGEPGSPGKQGLQGPKGDLGL 773 G G +G G G PG KG G+ G G KGDK G +G GSPG++G GP G +GL Sbjct: 965 GPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL 1023 Score = 399 bits (1025), Expect = e-111 Identities = 267/644 (41%), Positives = 314/644 (48%), Gaps = 135/644 (20%) Query: 241 ECEKGDPGDPGPPGTHGN----------PGIKGERGPKGNPGNAQKGEAGERGPGGIPGY 290 E E+GD GP PG GE+G KG P +KG+ E GP G PG Sbjct: 342 EDEEGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEKGQQFE-GPPGAPGP 399 Query: 291 KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG--------------DPGPK 336 +G G G G PG GD G PGP G G GI GI GPPG P Sbjct: 400 QGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPV 459 Query: 337 GFQ-------------GNKGEPGP------PGPYGSPGAPGI----GQQGIKGERGQEGR 373 FQ KG PGP PGP G PG PG+ G +G +G RG +G Sbjct: 460 SFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGP 519 Query: 374 PGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE-------------GFPGP 410 G PG +G G PG GP+G G G GLPGE G PG Sbjct: 520 HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGE 579 Query: 411 KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQ 469 GE+G+EGP GP G G G +G +GP G GP G PG+ G G G +G +GPPG Sbjct: 580 DGERGAEGPPGPTGQAG--EPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEP 637 Query: 470 GPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE 529 GP PG +G G G GP+G IG G KG PG+ PG PG+PG DG G G Sbjct: 638 GP-----PGQQGNHGSQGLPGPQGL--IGTPGEKGPPGN---PGIPGLPGSDGPLGHPGH 687 Query: 530 AGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG- 587 G G +G +GPPG G PG G G KG+ GN+G +G G +G G PG G G+ G Sbjct: 688 EGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGD 747 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPR- 646 PG PGP+G+ G G G G+ G GP G G +G +G PGL GYPG PGP+ Sbjct: 748 QGKPGAPGPRGEDGPEGPKGQAGQAG--EEGPPGSAGEKGKLGVPGL--PGYPGRPGPKG 803 Query: 647 --GLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPG 699 G PGP GP+G +G G TG G G RGPPG G RG G GPKGD GQ G PG Sbjct: 804 SIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPG 863 Query: 700 PPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGE--------------- 737 P G +G+ G QGP GFPGPKG GH G PGQ+GE Sbjct: 864 IP-----GEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGV 918 Query: 738 ---HGERGDVGKKGDKGEIGEPGSPGKQGL------QGPKGDLG 772 G+ G+VG G++G G PG PG+QGL +G KG+LG Sbjct: 919 LGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELG 962 Score = 392 bits (1008), Expect = e-109 Identities = 244/567 (43%), Positives = 285/567 (50%), Gaps = 115/567 (20%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG++G G KG G G G+ GP G+ G+ G KG G+ G Sbjct: 933 ERGPPGPPGPPGEQGLPGLEGREGAKGELG--PPGPLGKEGPAGLRGFPGPKGGPGDPGP 990 Query: 303 PGIKGDKGSPGPYG------------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGP 350 G+KGDKG PGP G P G G+ G +G G GP G +G++GE GPPGP Sbjct: 991 TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050 Query: 351 YGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGV 396 G G PG G G GE G +G GAPG G G PGQPG RGP G Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110 Query: 397 PGERGLPG----EGFPGPKGEKGSEGPTG------PQGLQGL-SIKGEKGDIGPVGPQGP 445 PG G G G PG G+KG +G G P GLQGL GEKG++G VG GP Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170 Query: 446 MGIPG-------IGSQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQ 485 G PG GS+G G+ G +G PG G G+ G+PG KG++G+ Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230 Query: 486 MGPTGPRGPVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532 G +GP G G G GP G PG +G PG PGV G DG+ G+KG+ Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGD--- 1287 Query: 533 PGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SI 590 PG G GPPG G+PG G GK+G G+ G+ G G +G KGEPG GP G G Sbjct: 1288 PGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGA 1347 Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD------------ 637 GPPG G G GIPG GEPGL G G GP GP G PGLKGD Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGL 1407 Query: 638 ----------------GYPGV---PGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPS 678 G PGV PGP+G PGPPGP +G G G PGV GP G Sbjct: 1408 IGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGP-----IGSLGHPGPPGVAGPLGQK 1462 Query: 679 GPRGV-GTQGPKGDTGQKGLPGPPGPP 704 G +G G+ GP+GDTG G PGPPG P Sbjct: 1463 GSKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 325 bits (834), Expect = 1e-88 Identities = 207/442 (46%), Positives = 234/442 (52%), Gaps = 44/442 (9%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKG 292 E+GD GD G PG G+ G KG+ GP G PG G G RGP G+ G KG Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQ---GNKGEPGPPG 349 D G RG G G G +G PGP G KG G G GP G PGP+G Q G++G PG PG Sbjct: 1134 DDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG 1193 Query: 350 PYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE-- 405 G PGA G G++G G+ G G PG PGP G +GE G GP G G PG++G PGE Sbjct: 1194 GVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG 1253 Query: 406 --GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP 462 G GP G G GP G G+ G+ GEKGD G VG GP G+ GE G GP Sbjct: 1254 AKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPP-----GASGEPGAPGP 1308 Query: 463 IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGE 520 G GP G G +G G KG G+ GP GP G G +G +GP G G GL G PG GE Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368 Query: 521 DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580 G G G+ G PG GP G PG KGD G KG KG+ G GL GP G GE G Sbjct: 1369 PGLLGAPGQMGPPGPLGP-----SGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQ 1423 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GY 639 G+PG + GPPGPKGD G PG G G P GP GV GP G G+ G G G Sbjct: 1424 ---GLPG--VQGPPGPKGDPGPPGPIGSLGHP-----GPPGVAGPLGQKGSKGSPGSMGP 1473 Query: 640 PGVPGPRGLPGPPG-PMGLRGV 660 G GP G PGPPG P L G+ Sbjct: 1474 RGDTGPAGPPGPPGAPAELHGL 1495 Score = 285 bits (729), Expect = 2e-76 Identities = 185/422 (43%), Positives = 217/422 (51%), Gaps = 52/422 (12%) Query: 389 GPRGPEGVPG--ERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPM 446 G +G +G P E+G EG PG G +G GP+GP G G GD GP GP G Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFP-----GDPGPPGPAGLP 427 Query: 447 GIPGIGSQGEQGIQGPIGP-------------PGPQGPAGQGLPGSKGEVGQMGPTGPRG 493 GIPGI GI+GP G GP Q + + Q+ GP G Sbjct: 428 GIPGI-----DGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPG 482 Query: 494 PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGD 552 PVG+ G PG +GLPG PG+ GE+GA G +G GL G GP G GK G+PG G Sbjct: 483 PVGL-----TGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGA 537 Query: 553 EGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEP 612 G G G +G RG G G GE G G FG G PGPPG G+RG G PG G+ Sbjct: 538 RGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQ--PGPPGEDGERGAEGPPGPTGQA 595 Query: 613 GLSIRGPKGVQGPRG---PVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKG 667 G GP+G+ GPRG P G PG+ G DG PG G G PG PGP G +G G G G Sbjct: 596 GEP--GPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPG 653 Query: 668 EPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725 G+ G PG GP G G G G G G PG GP G G+QG G GP G+PGP+G Sbjct: 654 PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRG 713 Query: 726 TMG----HGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTK 775 G GL G+KGE GE +GDVG KGD+G+ G PG G+ G +GPKG G Sbjct: 714 VKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAG 773 Query: 776 EE 777 EE Sbjct: 774 EE 775 Score = 39.3 bits (90), Expect = 0.021 Identities = 49/176 (27%), Positives = 61/176 (34%), Gaps = 43/176 (24%) Query: 638 GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGV--RGPPGPSGPRGVGTQGPKGDTGQK 695 G P P PR G RG G K + PP S T PK +T Sbjct: 237 GEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETPAP 296 Query: 696 GLPGPPGP---------------------PGYGSQ--------GIKGEQGPQGFPG---- 722 LP P P P G++ + E+G G Sbjct: 297 NLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPDFR 356 Query: 723 ----PKGTMGHGLPGQKGEHGERGD--VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 P T PG GE G +G+ V +KG + E G PG+PG QG+ GP G G Sbjct: 357 AAEYPSRTQFQIFPG-AGEKGAKGEPAVIEKGQQFE-GPPGAPGPQGVVGPSGPPG 410 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 459 bits (1182), Expect = e-129 Identities = 275/610 (45%), Positives = 318/610 (52%), Gaps = 95/610 (15%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 +G PG PG PG+ G PG G +G G PG G GP G PG G G +G G P Sbjct: 536 RGMPGSPGGPGSDGKPGPPGSQGESGRPG-----PPGPSGPRGQPGVMGFPGPKGNDGAP 590 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQG 363 G G++G PG GP+GP G G TGP G PGP G G+KG+ GPPGP G G PG G Sbjct: 591 GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG--- 647 Query: 364 IKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP----------GEGFPGPKG 412 G G+ G+PG PGP G G PG PG +G G PGERG P G G PGP+G Sbjct: 648 --GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG 705 Query: 413 EKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIG 464 KG+ GP GP G G + GE+G +G GP+G G PG G G+ G +GP G Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765 Query: 465 PPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPGV 517 P GP GPAGQ PG KGE G G G GP G G GP G PG+ G G+PG Sbjct: 766 PIGPPGPAGQ--PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGG 823 Query: 518 PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGN------QGQRGLPGP 570 GE GA G+KGE G PG GP G G G PGP+G +G++GS G G RGLPGP Sbjct: 824 KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGP 883 Query: 571 EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPV 629 G G PG GP G PG GPPGP G+ G PG PG G G G KG G +GP Sbjct: 884 PGSNGNPGPPGPSGSPGKD--GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPP 941 Query: 630 GAPGLKG----DGYPGVPGPRGLPGP---PGPMGLRG-VGDTGAKGEPGVRGPPGPSGPR 681 GAPG G G G+ GP G+PGP PGP G++G G GA G G RGPPGP G Sbjct: 942 GAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP 1001 Query: 682 GV----------------------GTQGPKGDTGQKGLPGPPGPPGY------------- 706 G+ G+ G KGD G+ G PG PG PG+ Sbjct: 1002 GLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKS 1061 Query: 707 GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 G +G G GP G PGP G+ G G G KGE GERG G KG +G G PG+PG Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP 1121 Query: 763 GLQGPKGDLG 772 G G +G +G Sbjct: 1122 GPAGQQGAIG 1131 Score = 446 bits (1147), Expect = e-125 Identities = 280/648 (43%), Positives = 315/648 (48%), Gaps = 122/648 (18%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 G G PGP G +G PG++G G G G + G GERG GIPG G KGE G+ G P Sbjct: 411 GARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSP 470 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS---------P 354 G G G PG G +G G +G GP G PG KG G +G PGP GP G+ P Sbjct: 471 GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530 Query: 355 GAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP--------- 403 G PG+ G G G G +G+PG PG G G PG PGP GP G PG G P Sbjct: 531 GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAP 590 Query: 404 -------GEGFPGPKGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQG 455 G G PGP+G G G TGPQG G G+KGD GP GPQG G+PG G G Sbjct: 591 GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG--G 648 Query: 456 EQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI----------------G 498 G G G PGP+G AG G PG KG+ G G GP G G G Sbjct: 649 PPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708 Query: 499 VQGPKGEPGSIGLPGQPGVPGED---GAAGKKGEAGLPGARGPEGPPGKGQP-------G 548 GP G PG+ G PG G+PGE G+ G KG+ G PG G +G PGK P G Sbjct: 709 AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768 Query: 549 PKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGP---G 604 P G G+ G KG G GLPG GP+G PG G G PG PG PG G+ GG G Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 605 IPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD----------------GYPGVPGPRG 647 PG KGE G + GP G GP GP G G+KG+ G PG PG G Sbjct: 829 APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNG 888 Query: 648 LPGPPGPMGLRG-------VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGD----- 691 PGPPGP G G G+TGA G PGV GP G +G G G QGP G Sbjct: 889 NPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLG 948 Query: 692 ----TGQKGLPGPPGPPG----YGSQGIKGEQ---------------GPQGFPGPKGTMG 728 TG +GL GPPG PG G QG+KGE GPQG PG GT G Sbjct: 949 IAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008 Query: 729 H----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G PG G G G G KGD+GE G PG+PG G GP G +G Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG 1056 Score = 444 bits (1141), Expect = e-124 Identities = 276/631 (43%), Positives = 324/631 (51%), Gaps = 105/631 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKP 303 G PG PGPPGT G+PG G G +G PG Q G +G GP G G G G+ GE G+P Sbjct: 177 GPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRP 236 Query: 304 GIKGDKGSPGPYGPKGPRGIQGI------------------TGPPGDPGPKGFQGNKGEP 345 G G++G PGP G KGP GI G TG PG G G G G P Sbjct: 237 GRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP 296 Query: 346 GPPGPYGSP---GAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPE 394 GP GP G+P G PG+ G +G G RG +G+PG PGP G G PG G GP Sbjct: 297 GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 395 GVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDI------------GPV 440 G PG G PG+ G PGP+G G++GP GP G+ G KGE G GP Sbjct: 357 GSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP 416 Query: 441 GPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ----GLPGSKGEVGQMGPTGPRGPV 495 GP G G PG+ G GE G G G PGP+G G+ G+PG+KGE G+ G G G Sbjct: 417 GPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN 476 Query: 496 GI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK---------- 544 G+ G G +G PG G G G+PGE G AG++G G G RG G PG+ Sbjct: 477 GLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMR 536 Query: 545 ---GQPGPKGDEGKKGSKGNQGQRGL---PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598 G PG G +GK G G+QG+ G PGP GP+G+PG+MG G G G PG G Sbjct: 537 GMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND--GAPGKNG 594 Query: 599 DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD----------GYPGV---PGP 645 +RGGPG PG +G PG + G G QGP GP G G KGD G PG PG Sbjct: 595 ERGGPGGPGPQGPPGKN--GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGE 652 Query: 646 RGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGP 700 G PG PGP G G G G G PG RGPPG +G G+ G GP G G KG GP Sbjct: 653 NGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP 712 Query: 701 PGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERGDV----- 744 PGPPG G QG+ GE+G G PGPKG G G+PG+ G G G + Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772 Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G+ GDKGE G PG PG G +G G+ G T Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSPGERGET 803 Score = 443 bits (1140), Expect = e-124 Identities = 274/613 (44%), Positives = 314/613 (51%), Gaps = 90/613 (14%) Query: 245 GDPGDPGPPGTHG---NPGIKGERGPKGNPGN----AQKGE------AGERGPGGIPGYK 291 G PG PGPPGT G +PG KGE GP G+PG+ Q+GE AG +GP G PG Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389 Query: 292 GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G +GE G GI G G G GP GP G G G G G G G KGEPGP G Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPG 404 G G PG+ G KGE G++G PG PG G+ G PG GP GP G+PGE+G G Sbjct: 450 GEAGIPGV--PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQG----------------------LSIKGEKGDIGPVG 441 E G PGP G +G+ G G G+ G +GE G GP G Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG 567 Query: 442 PQGPMGIPGI----------GSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVG 484 P GP G PG+ G+ G+ G +G G PGPQGP G QG PG G G Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627 Query: 485 QMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543 G TGP GP G+ G+ G G PG G PG+PG G+ GA G G G GA G GPPG Sbjct: 628 DKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPG 687 Query: 544 -KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG 602 G PG +G G G +G +G G PGP G G PG+ G G G G PGPKGD+G Sbjct: 688 LAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL--GSPGPKGDKGE 745 Query: 603 PGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGLKGDG----YPGVPGPRGLPG------P 651 PG PG G PG RGP G GP GP G PG KG+G PG+ GPRG PG P Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP 805 Query: 652 PGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGI 711 PGP G G G GEPG +G G G +G G GP G G G GP GPPG QG+ Sbjct: 806 PGPAGFPGA--PGQNGEPGGKGERGAPGEKGEG--GPPGVAGPPGGSGPAGPPG--PQGV 859 Query: 712 KGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPG------SPGKQGL 764 KGE+G G PG G G GLPG G +G G G G G+ G PG +PG G+ Sbjct: 860 KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919 Query: 765 QGPKGDLGLTKEE 777 GPKGD G E+ Sbjct: 920 SGPKGDAGQPGEK 932 Score = 436 bits (1122), Expect = e-122 Identities = 266/578 (46%), Positives = 300/578 (51%), Gaps = 62/578 (10%) Query: 243 EKGDPGDPGP---PGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERG 298 E G PG GP PG G PG+ G G +GN G G+ G GP G G+ G G +G Sbjct: 292 ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKG 351 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 E G G G G+PG G GP+G G GPPG PG G G KGE GP G PGAPG Sbjct: 352 EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPA---GIPGAPG 408 Query: 359 I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416 + G +G G G G PG G G GEPG+ G +G G GERG G G PG KGE G Sbjct: 409 LMGARGPPGPAGANGAPGLRG--GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGK 466 Query: 417 EGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPG------- 467 +G G G GL GE+G G GP GP GIPG G GE+G GP GP G Sbjct: 467 DGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526 Query: 468 ---PQGPAGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGE 520 P GP +G+PGS G G G GP G G G GP G G G+ G PG G Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGN 586 Query: 521 DGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 DGA GK GE G PG GP+GPPGK G+ GP+G G G G++G G PGP+G +G PG Sbjct: 587 DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT 646 Query: 580 MGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-G 638 GP G G PG PGPKGD G PG PG KG+ G G +GP G GAPGL+G G Sbjct: 647 GGPPGENGK--PGEPGPKGDAGAPGAPGGKGD-----AGAPGERGPPGLAGAPGLRGGAG 699 Query: 639 YPGVPGPRGLPGPPGPMGLRGV-------------------GDTGAKGEPGVRGPPGPSG 679 PG G +G GPPGP G G GD G G PG G PG G Sbjct: 700 PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDG 759 Query: 680 PRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQ 734 PRG +G GP G G KG G PG PG G +G GE+G G PGP G G PGQ Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGF--PGAPGQ 817 Query: 735 KGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 GE G +G+ G G+KGE G PG G G GP G G Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPG 855 Score = 431 bits (1107), Expect = e-120 Identities = 278/661 (42%), Positives = 314/661 (47%), Gaps = 134/661 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP------------------G 285 KGDPG PG PG +G+PGI G+ G G+PG E+ GP G Sbjct: 108 KGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVG 167 Query: 286 GIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF------- 338 G+ GY G G G G PG G GSPG G +GP G G GP G PGP G Sbjct: 168 GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA 227 Query: 339 --QGNKGEPGPPGPYGSPGAPGI-------------GQQGIKGERGQEGRPGAPGPIG-- 381 G G PG PG G PG PGI G +G G G++G GAPG G Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287 Query: 382 --VGEPGQPGPRGPEGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQGL-SIK 431 GE G PGP GP G PGERG PG G G +G G GP GP G G Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSP 347 Query: 432 GEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSK 480 G KG++GP G G G PG G QG G QGP GPPG G G G+PG+ Sbjct: 348 GAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407 Query: 481 GEVGQMGPTGPRGPVGI----------------GVQGPKGEPGSIGLPGQPGVPGEDGAA 524 G +G GP GP G G G GP+GE G G+PG PG GEDG Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 525 GKKGEA---GLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMG 581 G GE GLPGA G G P G GP G G G KG G+RG PGP GP+G G G Sbjct: 468 GSPGEPGANGLPGAAGERGAP--GFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPG 525 Query: 582 PFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGP---VGAPGL 634 G+PG +PG PG G G PG PG +GE G GP G GPRG +G PG Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP--GPPGPSGPRGQPGVMGFPGP 583 Query: 635 KG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGP------PGPSGPRGV--- 683 KG DG PG G RG PG PGP G G G+TG +G PG GP GP GP+G+ Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL 643 Query: 684 -GTQGPKGDTGQKGLPGPPG-------PPGYGSQGIKGEQGPQGF------------PGP 723 GT GP G+ G+ G PGP G P G G G GE+GP G PGP Sbjct: 644 PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703 Query: 724 KGTMG----------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 +G G G PG +G GERG +G G KG+ GEPG PG G+ G G G Sbjct: 704 EGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGP 763 Query: 774 T 774 T Sbjct: 764 T 764 Score = 417 bits (1071), Expect = e-116 Identities = 264/598 (44%), Positives = 308/598 (51%), Gaps = 84/598 (14%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGI--------PGYKGDKGER 297 P GP G G+PG G G G+PG Q G G GP GI Y Sbjct: 99 PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSY 158 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 + G G PGP GP GP G G +G PG PG G+QG GEPG GP G PG P Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218 Query: 358 G-IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKG 415 G IG G G+ G+ GRPG PG G+ PG PG +GP G+PG G+ G GF G GEKG Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGL--PGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG 276 Query: 416 SEGPTGPQGLQGLSIKGEKGDIGPVGPQGP------MGIPGI----GSQGEQGIQGPIGP 465 G G +G GL GE G GP+GP+G G+PG G+ G +G G GP Sbjct: 277 ETGAPGLKGENGL--PGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGP 334 Query: 466 PGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGA 523 PGP G AG G PG+KGEVG G G G G G GP+G G+ G PG PG+ G G Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394 Query: 524 AGKKGEAGLP------GARGPEGPP----------GKGQPGPKGDEGKKGSKGNQGQRGL 567 G+ G AG+P GARGP GP G G+PG G +G+ G +G +G+ G+ Sbjct: 395 KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454 Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGP---------GIPGFKGEPGLSIRG 618 PG G KGE G G G PG + G PG G+RG P GIPG KG G RG Sbjct: 455 PGVPGAKGEDGKDGSPGEPGAN--GLPGAAGERGAPGFRGPAGPNGIPGEKGPAG--ERG 510 Query: 619 PKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGP 677 G GPRG G PG DG PG PG RG+PG PG G G G G++GE G GPPGP Sbjct: 511 APGPAGPRGAAGEPG--RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGP 568 Query: 678 SGPRG----VGTQGPKGD------TGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTM 727 SGPRG +G GPKG+ G++G PG PGP G G GE GPQG PGP G Sbjct: 569 SGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP--QGPPGKNGETGPQGPPGPTGPG 626 Query: 728 G-------------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G GLPG G GE G G+ G KG+ G PG+PG +G G G+ G Sbjct: 627 GDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERG 684 Score = 324 bits (830), Expect = 3e-88 Identities = 220/552 (39%), Positives = 252/552 (45%), Gaps = 139/552 (25%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP---GGIPGYKGDKGERGE 299 + G PG+ GPPG G PG++G GP G G KG AG GP G PG +G GERG Sbjct: 676 DAGAPGERGPPGLAGAPGLRGGAGPPGPEGG--KGAAGPPGPPGAAGTPGLQGMPGERGG 733 Query: 300 CGKPGIKGDKGSPG------------PYGPKGPRGIQGITGPPGDPG------------P 335 G PG KGDKG PG P GP GP G G G PGD G P Sbjct: 734 LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP 793 Query: 336 KGFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEP----GQPGP 390 +G G +GE GPPGP G PGAPG G+ G KGERG G G GP GV P G GP Sbjct: 794 RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853 Query: 391 RGPEGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLS----------- 429 GP+GV GERG PG G PGP G G+ GP GP G G Sbjct: 854 PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913 Query: 430 -----IKGEKGDIG------------PVGPQGPMGIPGI----GSQGEQGIQGPIGPPGP 468 + G KGD G P G GP+GI GI G G G+ GP G PGP Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973 Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRG----------------------------PVGIGV 499 QG G+ G PG+ G G+ GP GP+G P G G Sbjct: 974 QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033 Query: 500 QGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGP------ 549 +G G PG+ G PG PG PG G AGK G+ G G GP G PG +G PGP Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093 Query: 550 KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGF 608 KG+ G++G+ G +G RG PG G G PG G G G+ P GP GP G G PG G Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153 Query: 609 KGEPG-LSIRGPKGVQGPRG------------PVGAPGLKGDGYPGVPGPRGLPGPPGPM 655 G PG + GP+G +G RG P G P G PGP G G Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPP--------GAPGP--CCGGVGAA 1203 Query: 656 GLRGVGDTGAKG 667 + G+G A G Sbjct: 1204 AIAGIGGEKAGG 1215 Score = 303 bits (777), Expect = 5e-82 Identities = 184/434 (42%), Positives = 219/434 (50%), Gaps = 72/434 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G+ G PGP G G PG GE G KG G GE GE GP G+ G G G G G Sbjct: 799 ERGETGPPGPAGFPGAPGQNGEPGGKGERG--APGEKGEGGPPGVAGPPGGSGPAGPPGP 856 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPG---DPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G+KG++GSPG G G G +G+ GPPG +PGP G G+ G+ GPPGP G+ GAPG Sbjct: 857 QGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGS 916 Query: 359 ---------IGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGL 402 GQ G KG G +G PGAPGP+G+ G G PG GP G PG +G+ Sbjct: 917 PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976 Query: 403 PGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI---------- 451 GE G PG G G GP GPQGL GL+ G G+ G G G G+PG Sbjct: 977 KGESGKPGANGLSGERGPPGPQGLPGLA--GTAGEPGRDGNPGSDGLPGRDGSPGGKGDR 1034 Query: 452 ---GSQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPV 495 GS G G G GPPGP GPAG+ G PG G G GP GPRG Sbjct: 1035 GENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDK 1094 Query: 496 G-------IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK---- 544 G G++G +G PG+ G PG PG G+ GA G G AG G GP GPPGK Sbjct: 1095 GETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTS 1154 Query: 545 ------GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598 G PGP+G+ G++GS+G+ G G PGP GP G PG G G G Sbjct: 1155 GHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC----CGGVGAAAIAGIGG 1210 Query: 599 DRGGPGIPGFKGEP 612 ++ G P + EP Sbjct: 1211 EKAGGFAPYYGDEP 1224 Score = 155 bits (393), Expect = 2e-37 Identities = 101/243 (41%), Positives = 114/243 (46%), Gaps = 34/243 (13%) Query: 538 PEGPP-GKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGP 596 P PP G+G GPKGD G G G G G+PG G G PG PG P GP Sbjct: 95 PTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPG------PPGICESCPTGP 148 Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPM 655 + P + + G+++ G G GP GP G PG G G+PG PG G GPPG Sbjct: 149 QNY--SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG-- 204 Query: 656 GLRGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKG 713 EPG GP GP GP G +G GP G G+ G PG PG G G GIKG Sbjct: 205 ------------EPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252 Query: 714 EQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G GFPG KG G G+ GE GE G G KG E G PG+ G GP G G Sbjct: 253 PAGIPGFPGMKGH--RGFDGRNGEKGETGAPGLKG------ENGLPGENGAPGPMGPRGA 304 Query: 774 TKE 776 E Sbjct: 305 PGE 307 Score = 147 bits (372), Expect = 4e-35 Identities = 91/208 (43%), Positives = 105/208 (50%), Gaps = 19/208 (9%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 ++G+ G PG PG G+PG G GP G G+ +GE+G GP G PG G +G G G Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKSGD--RGESGPAGPAGAPGPAGSRGAPGPQGP 1090 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362 G KG+ G G G KG RG G G PG PGP G QG G PGP GP G G Sbjct: 1091 RGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP------ 1144 Query: 363 GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGP-T 420 G G++G G PGPI G PGPRG G G G PG G PGP G G+ GP Sbjct: 1145 --SGPPGKDGTSGHPGPI-----GPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCC 1197 Query: 421 GPQGLQGLS-IKGEK-GDIGPVGPQGPM 446 G G ++ I GEK G P PM Sbjct: 1198 GGVGAAAIAGIGGEKAGGFAPYYGDEPM 1225 Score = 33.5 bits (75), Expect = 1.2 Identities = 21/54 (38%), Positives = 22/54 (40%), Gaps = 5/54 (9%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDK 294 E G PG PGPPG G PG G G A G GG Y GD+ Sbjct: 1175 EGSPGHPGQPGPPGPPGAPG-----PCCGGVGAAAIAGIGGEKAGGFAPYYGDE 1223 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 452 bits (1162), Expect = e-126 Identities = 309/783 (39%), Positives = 378/783 (48%), Gaps = 133/783 (16%) Query: 107 PFSSWKDLQTFKQKVKSMNLIG-QGTFSYYAISNATRLL---KREGRKDGVKVVLLMTDG 162 P + DL Q+++ M + G A+ A R + GR+ V V+++ Sbjct: 1107 PLNGSHDLGIILQRIRDMPYMDPSGNNLGTAVVTAHRYMLAPDAPGRRQHVPGVMVLL-- 1164 Query: 163 IDHPKNPDVQSISEDARISGISFITIALSTVVNEAKLRLISGDSSSEPTLLLSDPTLVDK 222 +D P D+ S +A+ SG++ + + ++ E RL G S + + D +D+ Sbjct: 1165 VDEPLRGDIFSPIREAQASGLNVVMLGMAGADPEQLRRLAPGMDSVQTFFAVDDGPSLDQ 1224 Query: 223 IQDRL-----DILFEKKCERKICE--CEKGDPGDPG---------PPGTHGNPGIKGERG 266 L F + + C C KG G+PG PPG G PG G G Sbjct: 1225 AVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPG 1284 Query: 267 PKGNPGNAQ-KGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQG 325 P+G PG+A KGE G G G PG G G G G PG+KG G PGP G G RG +G Sbjct: 1285 PQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRG 1344 Query: 326 ITGPPGDPGP------KGFQGNKGEPGP------------PGPYGSPGAPGIGQQGIKGE 367 G PG PG G G KG+PGP PGP G PG PG +G KG+ Sbjct: 1345 PKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGD 1404 Query: 368 RGQEGRPG------APGPIGV-GEPGQPGPRGPEGVPGERGLPGE------GFPGPKGEK 414 RG+ G PG APG G+ G PG PGP+GP G PG++G G+ G PG G Sbjct: 1405 RGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP 1464 Query: 415 GSEGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIG 464 G +GP GP G G L GEKG+ GP GP G G+PG+ G G +GP G Sbjct: 1465 GEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVA--GRPGAKGPEG 1522 Query: 465 PPGPQGPAGQ----GLPGS-----------KGEVGQMGPTGPRGPVGI------------ 497 PPGP G G+ G PG KGE G +GP GPRG G+ Sbjct: 1523 PPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLP 1582 Query: 498 GVQGPKGEPGS---IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQP 547 G GPKG+PG IGL G+ G PG+ G G+KG+ G PG GP GP G KG Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642 Query: 548 GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-IPGPPGPKGDRGGPGIP 606 GP GD G G G +G RG PG GP GE G G G G + PG GPKGDRG PG P Sbjct: 1643 GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPP 1702 Query: 607 GFKGE-----PGLSIRGP---KGVQGPRGPVGAPGLKGDGYPGVPGPRGLPG---PPGPM 655 G G PG +G +G +GPRGP G PGL PG PG RG+ G PPGP Sbjct: 1703 GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGL-----PGAPGERGIEGFRGPPGPQ 1757 Query: 656 GLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGE 714 G GV G GE G RGPPG G G+ G G G +G G G G PG G+ G Sbjct: 1758 GDPGV--RGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPG--RDGLPGL 1813 Query: 715 QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 +G QG PGP G G LPG+ GE G K G G+ GEPG PG+ G +G KGD G + Sbjct: 1814 RGEQGLPGPSGPPG--LPGKPGEDG------KPGLNGKNGEPGDPGEDGRKGEKGDSGAS 1865 Query: 775 KEE 777 E Sbjct: 1866 GRE 1868 Score = 426 bits (1095), Expect = e-119 Identities = 270/625 (43%), Positives = 327/625 (52%), Gaps = 101/625 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGI------PGYKGDKGE 296 E+G+ G GPPG G PG G GPK + G +GE+GP G+ PG GD+G Sbjct: 2068 ERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGP 2127 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 +G+ G PGIKGD+G PGP G G G+ G G G G G QG +G PGP G +G PG Sbjct: 2128 KGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGP 2187 Query: 357 PGI----------GQQGIKGERGQEGRP--GAPGPIG-VGEPGQPGPRGPEGVPGERGLP 403 PG G G+KGE G+ G P G GP G VG PG PGP G G G GLP Sbjct: 2188 PGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLP 2247 Query: 404 GE----GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG------IG 452 G+ G PG G G+ G G +G G+ G G +GP G GP G PG G Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307 Query: 453 SQGEQGIQGP-----IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPK 503 ++GE+G G +G PG +G +GLPG +GE G+ G G G G G GPK Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKG--DRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK 2365 Query: 504 GEPG--SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKG 557 G G +G+PG PG PG G G G GLPGA G G PG +G+ G G G++G Sbjct: 2366 GFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERG 2425 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP------GPPGPKGDRGGPGIPGFKGE 611 G G+ G+PGP GP G PG +GP G G G PGP+G+RG PGI G G Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGR 2485 Query: 612 PGLSIRGPKGVQGP---------RGPVGAPGLKGD-----------------GYPGVPGP 645 PG GP+G+ GP +G VG+ GLKGD G G GP Sbjct: 2486 PGQ--EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP 2543 Query: 646 RGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPP 704 RGL G GP G G GD G+KGEPG +G G G RG+ GP+G G G+PG PG P Sbjct: 2544 RGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL--LGPQGQPGAAGIPGDPGSP 2601 Query: 705 GY-GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERGDVGK---KGDKGEI 753 G G GI+GE+G GF GP+G G GL G+KG+ GE G G+ G KGE+ Sbjct: 2602 GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEM 2661 Query: 754 GEP------GSPGKQGLQGPKGDLG 772 GEP G+PGK+GL GPKGD G Sbjct: 2662 GEPGVPGQSGAPGKEGLIGPKGDRG 2686 Score = 415 bits (1067), Expect = e-115 Identities = 293/734 (39%), Positives = 345/734 (47%), Gaps = 204/734 (27%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300 G GD G PG G G KGERGP G G+ G G +GP G PG G +GE+GE Sbjct: 1477 GPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEP 1536 Query: 301 GKPGI-----------KGDKGSPGPYGPKGPRGIQGITGPPG-----DPGPKGFQGNKG- 343 G+PG KG+KG GP GP+G G+QG GPPG DPGPKG G++G Sbjct: 1537 GRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP 1596 Query: 344 -----------EPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV--- 382 + GPPG G PG PG G+ G GE+G EG PG PG G Sbjct: 1597 IGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE 1656 Query: 383 -GEPGQPGPRGPEGVPGERGLPGE-------GFPGPKGEKGSEGPTGPQGL-----QGLS 429 G G PG RGP G G++G PGE G GPKG++G GP GP G G Sbjct: 1657 RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAR 1716 Query: 430 IKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGP 488 KGE GD G GP+GP G PG+ G+ GE+GI+G GPPGPQG G + G GE G GP Sbjct: 1717 EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG--VRGPAGEKGDRGP 1774 Query: 489 TGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK--- 544 G G G+ G G G G G G+ G PG DG G +GE GLPG GP G PGK Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834 Query: 545 ----------GQPGPKGDEGKKGSKGN------------QGQRGLPGPEGPKGEPGIMGP 582 G+PG G++G+KG KG+ +G+RG PG GP+G PG+ GP Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894 Query: 583 FGMPGTSIPGPPG---PKGDRGG---------PGIPGFKGEPG----------------- 613 G PG PG PG PKGDRG PG G +GEPG Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKAS 1954 Query: 614 ----------------LSI----RGPKG---VQGP---RGPVGAPG---LKGD-GYPGVP 643 L + RGPKG QGP GP+G PG LKGD G PG Sbjct: 1955 ALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ 2014 Query: 644 GPRGLP----GPPGPMGLRG----------------VGDTGAKGE--------------- 668 GP GL GPPGP GL G VG+ G GE Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074 Query: 669 ------PGVRGPPGPSGPR------GVGTQGPKGDTGQKGLPGPPGPPG----YGSQGIK 712 PG GPPGP GP+ G G G +G G KG G PG G G +G+ Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134 Query: 713 GEQGPQGFPGPKGTMGH-GLPGQKGE---------HGERGDVGKKGDKGEIGEPGSPGKQ 762 G +G +G PGP+G G+ GLPG++G G RG G G G+ G PG+PG Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194 Query: 763 GLQGPKGDLGLTKE 776 G GP+G GL E Sbjct: 2195 GPAGPQGPSGLKGE 2208 Score = 413 bits (1061), Expect = e-115 Identities = 294/749 (39%), Positives = 339/749 (45%), Gaps = 226/749 (30%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPK--------GNPGNAQKGEAGERGPGGIPGYKGDKGE 296 G PG PGP G G PG KGE+G G PG+ GE G RGP G G KGD+G Sbjct: 1427 GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP--GEQGPRGPPGAIGPKGDRGF 1484 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGI---QGITGPPGDPGPKGFQGNKGEPGPP----- 348 G G+ G KG++G PGP G +G G+ G GP G PGP G QG KGEPG P Sbjct: 1485 PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAV 1544 Query: 349 ---------------GPYGSPGAPGI---------------------------------- 359 GP G GA G+ Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG 1604 Query: 360 --GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVP---GERGL----- 402 G G GE+G GRPG PGP+G VGE G GP G G+P GERGL Sbjct: 1605 PPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPG 1664 Query: 403 -------------PGE-------GFPGPKGEKGSEGPTGPQGL-----QGLSIKGEKGDI 437 PGE G GPKG++G GP GP G G KGE GD Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDR 1724 Query: 438 GPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG 496 G GP+GP G PG+ G+ GE+GI+G GPPGPQG G+ G GE G GP G G G Sbjct: 1725 GQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG--DPGVRGPAGEKGDRGPPGLDGRSG 1782 Query: 497 I-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----------- 544 + G G G G G G+ G PG DG G +GE GLPG GP G PGK Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842 Query: 545 --GQPGPKGDEGKKGSKGN------------QGQRGLPGPEGPKGEPGIMGPFGMPGTSI 590 G+PG G++G+KG KG+ +G+RG PG GP+G PG+ GP G PG Sbjct: 1843 KNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGF 1902 Query: 591 PGPP---GPKGDRGG---------PGIPGFKGEPG------------------------- 613 PG P GPKGDRG PG G +GEPG Sbjct: 1903 PGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVET 1962 Query: 614 --------LSI----RGPK---GVQGP---RGPVGAP---GLKGD-GYPGVPGPRGLP-- 649 L + RGPK G QGP GP+G P GLKGD G PG GP GL Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALG 2022 Query: 650 --GPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 GPPGP GL G G G G PG RG G G R G QG G G Sbjct: 2023 ERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGER--GEQGRDGPPGL 2080 Query: 695 KGLPGPPGPPG------YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV 744 G PGPPGPPG G+ GEQGP G G KG G G G +G G +GD Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDR 2140 Query: 745 GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G+ G +G+ G PG PG++G+ GP+G GL Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169 Score = 412 bits (1059), Expect = e-115 Identities = 288/682 (42%), Positives = 332/682 (48%), Gaps = 158/682 (23%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGN--PGN-AQKGEAGERGPGGIPGYKGDKGERGEC 300 KG+ GD GP G G G++GERGP G PG+ KG+ G+RGP G+ G G G+ G Sbjct: 1553 KGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGP- 1611 Query: 301 GKPGIKGDKGSPGPYGPKGPR------GIQGITGPPGDP------GPKGFQGNKGEPGPP 348 PG KGD G PGP GP GPR G +G GPPGDP G +G +G G GP Sbjct: 1612 --PGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPV 1669 Query: 349 GPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-----------VGEP---GQPGP 390 G G G PG G G G +G G PG PGP G GEP GQ GP Sbjct: 1670 GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGP 1729 Query: 391 RGPEGVPGERGLPGE-------GFPGPKGEKGSEGPT------GPQGLQGLS-IKGEKGD 436 RGP+G PG G PGE G PGP+G+ G GP GP GL G S + G+ G Sbjct: 1730 RGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA 1789 Query: 437 IGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQGPAGQ----------GLPGS 479 GP GP G G G G +GEQG+ GP GPPG G G+ G PG Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGD 1849 Query: 480 KGEVGQM---------------GPTGPRGPVGI-GVQGPKGEPGSIGLPGQ--PGVP--- 518 GE G+ GP G RG GI G QGP G PG +G PGQ PGVP Sbjct: 1850 PGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGT 1909 Query: 519 ---GEDGAAGKKGEAGLPGARGPEGPPG-------------------------------- 543 G+ G G KGE GLPG RG G PG Sbjct: 1910 GPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGS 1969 Query: 544 -----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSI--PGPPGP 596 + + GPKGD G++G G +G G PG G KG+ G GP G PG ++ GPPGP Sbjct: 1970 FLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGP 2029 Query: 597 KGDRGGPGIPGFKGEP----GLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGP 651 G G PG PG G P G+ G G +G RG G G +G DG PG+PG G PGP Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP 2089 Query: 652 PGPM--------GLRG----VGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLP 698 PGP GL G G GAKGEPG G GP G RGV G +G +G+ G +G Sbjct: 2090 PGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQD 2149 Query: 699 GPPGPPG----YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGD---KG 751 G PG PG G +G G QGP+G PGP G GHG PG G G G G +G KG Sbjct: 2150 GNPGLPGERGMAGPEGKPGLQGPRGPPGPVG--GHGDPGPPGAPGLAGPAGPQGPSGLKG 2207 Query: 752 EIGEPGSPGKQGLQGPKGDLGL 773 E GE G PG+ GL GP G +GL Sbjct: 2208 EPGETGPPGR-GLTGPTGAVGL 2228 Score = 410 bits (1054), Expect = e-114 Identities = 260/636 (40%), Positives = 313/636 (49%), Gaps = 129/636 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG----NAQKGEAGERGPGGIPGYKGDKGERGEC 300 G+ G PG G G PG G++GPKG+ G +GE G RG G PG G++G G Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE 2164 Query: 301 GKPGIKGDKGSPGP---YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-------- 349 GKPG++G +G PGP +G GP G G+ GP G GP G +G GE GPPG Sbjct: 2165 GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTG 2224 Query: 350 ---------------PYGSPGAPG----------------IGQQGIKGERGQEGRPGAPG 378 P GSPG PG G+ G +G G G PG PG Sbjct: 2225 AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284 Query: 379 PIG-----------------------------------VGEPGQ------PGPRGPEGVP 397 P+G VGEPG PGPRG +G Sbjct: 2285 PVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEA 2344 Query: 398 GERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG------- 450 G G PG+ PG G+KG+ GP G +G G+ + G G GP G +G +G+PG Sbjct: 2345 GRAGEPGD--PGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGV 2402 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGE 505 +G G+ G +G +G PGP G G G PG +G G +GP GP G VG G++G KG+ Sbjct: 2403 VGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462 Query: 506 PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQ 564 PG +GLPG G GE G G+ G G G RG GPPG +G+ G KGD G G KG++G Sbjct: 2463 PG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGD 2521 Query: 565 R----GLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620 G PGP G KG+ G GP G+ G GP+GD G PG G KGEP Sbjct: 2522 SAVILGPPGPRGAKGDMGERGPRGLDGDK-----GPRGDNGDPGDKGSKGEP-------- 2568 Query: 621 GVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPS 678 G +G G PGL+G G G PG G+PG PG G GV G G KG+ G GP G Sbjct: 2569 ---GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLK 2625 Query: 679 GPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKG 736 G RGV G G G+ G KG GPPG PG G KGE G G PG G G GL G KG Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRPGLA--GHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683 Query: 737 EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 + G G G KGD+GE GE G+PG G GP G+ G Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDG 2719 Score = 409 bits (1050), Expect = e-113 Identities = 247/541 (45%), Positives = 289/541 (53%), Gaps = 37/541 (6%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306 PG+PG PG G+PG +G GP G G E G G G PG G++G RG G G K Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479 Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKG 366 GD+G PGP G G +G + GPPG G +G G G PG GP G PG G+QG KG Sbjct: 1480 GDRGFPGPLGEAGEKGER---GPPGPAGSRGLPGVAGRPGAKGPEGPPGP--TGRQGEKG 1534 Query: 367 ERGQEGRPGAPGPIGVGEPGQ------PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 E G+ G P GP G G+ GPRG GV GERG PG PG G KG G Sbjct: 1535 EPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDR 1594 Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQ-GLPG 478 GP GL G + G GD GP G +G G PG G G +G G +G G +GP G GLPG Sbjct: 1595 GPIGLTGRA--GPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPG 1652 Query: 479 SKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGP 538 GE G G G RGPV G +G +G+PG G G PG G G G+ G G PG Sbjct: 1653 KAGERGLRGAPGVRGPV--GEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710 Query: 539 EGPPG--KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGP 596 GP KG+PG +G EG +G KG+ G G PG G +G G GP G PG + GP G Sbjct: 1711 TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPG--VRGPAGE 1768 Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPP 652 KGDRG PG+ G G + G G GP GP GA G G DG PG+ G +GLPGP Sbjct: 1769 KGDRGPPGLDGRSG-----LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPS 1823 Query: 653 GPMGLRGVGDTGAKGEPGVRGPPG-PSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQG 710 GP GL G G G+PG+ G G P P G +G KGD+G G G GP G G+ G Sbjct: 1824 GPPGL--PGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPG 1881 Query: 711 IKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 I G QGP G PGP G G G PG G G +GD G+ G K GE G PG++GL+G G Sbjct: 1882 ILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSK---GEQGLPGERGLRGEPGS 1938 Query: 771 L 771 + Sbjct: 1939 V 1939 Score = 210 bits (535), Expect = 5e-54 Identities = 134/311 (43%), Positives = 161/311 (51%), Gaps = 33/311 (10%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-----------QKGEAGERGPGGIPG 289 E +G G PG G G G G G KG+ G++ KG+ GERGP G+ Sbjct: 2489 EGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGL-- 2546 Query: 290 YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349 GDKG RG+ G PG KG KG PG G G G++G+ GP G PG G G+ G PG G Sbjct: 2547 -DGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDG 2605 Query: 350 PYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE 405 G G G +G +G+KGERG +G G G G+ G+ GP G G+ G +G GE Sbjct: 2606 VPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGE--KGDKGEAGPPGRPGLAGHKGEMGE 2663 Query: 406 -GFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGP 462 G PG G G EG GP+G +G + G KGD G G +G GI G G G G GP Sbjct: 2664 PGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGP 2723 Query: 463 IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521 GPPG GP G +GL G KGE RGP G V G G PG+ G G+ G PG Sbjct: 2724 PGPPGSVGPRGPEGLQGQKGE---------RGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774 Query: 522 GAAGKKGEAGL 532 G G+KGEA L Sbjct: 2775 GPRGEKGEAAL 2785 Score = 174 bits (440), Expect = 6e-43 Identities = 103/252 (40%), Positives = 133/252 (52%), Gaps = 25/252 (9%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQ-KGEAGERGPGGIPGYKGDKGERGECG 301 +KG G+PG G+ G PG++G GP+G PG A G+ G G G+PG +G+KG+ G G Sbjct: 2561 DKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMG 2620 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQ 361 G+KG++G G G G +G +G GPPG PG G +G GEPG PG G+PG G+ Sbjct: 2621 PRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGL-- 2678 Query: 362 QGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTG 421 G KG+RG +G+PG G GE G+ G G G PG G +G GP G GS GP G Sbjct: 2679 IGPKGDRGFDGQPGPKGD--QGEKGERGTPGIGGFPGPSG--NDGSAGPPGPPGSVGPRG 2734 Query: 422 PQGLQGLS------------------IKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463 P+GLQG GE+G+ G GP GP G G + E I+G + Sbjct: 2735 PEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFV 2794 Query: 464 GPPGPQGPAGQG 475 Q A QG Sbjct: 2795 RQEMSQHCACQG 2806 Score = 64.7 bits (156), Expect = 5e-10 Identities = 50/190 (26%), Positives = 91/190 (47%), Gaps = 17/190 (8%) Query: 798 ELVFVIDSSESVGPENFQIIKNFVK--TMADRVALDLATARIGIINYSHKVEKVANLKQF 855 ++VF++D S S+G NF+ +++F++ + A R + YS L Sbjct: 38 DIVFLLDGSSSIGRSNFREVRSFLEGLVLPFSGAASAQGVRFATVQYSDDPRTEFGLDAL 97 Query: 856 SSKDDFKLAVDNMQYLGEGTYTATA-LQAANDMF--EDARPGVKKVALVITDGQTDSRDK 912 S D A+ + Y G T T A L A+ +F + ARPGV KV ++ITDG + + Sbjct: 98 GSGGDVIRAIRELSYKGGNTRTGAAILHVADHVFLPQLARPGVPKVCILITDG----KSQ 153 Query: 913 EKLTEVVKNASDTNVEIFVIGVVKKNDPNFEIFHKEMNLIATDP-EHVYQFDDFFTLQDT 971 + + + V++F +G +K DP +E+ +A+ P + F + F++ T Sbjct: 154 DLVDTAAQRLKGQGVKLFAVG-IKNADP------EELKRVASQPTSDFFFFVNDFSILRT 206 Query: 972 LKQKLFQKIC 981 L + +++C Sbjct: 207 LLPLVSRRVC 216 Score = 48.5 bits (114), Expect = 3e-05 Identities = 38/141 (26%), Positives = 53/141 (37%), Gaps = 33/141 (23%) Query: 986 SYLVQIFGSS-SPQPGFGMSGEELSESTPEPQKEISESLSVTRDQDEDDKAPEPTWADDL 1044 SY GS P +S E E P E SE + ++ +D +AP W D Sbjct: 2818 SYAADTAGSQLHAVPVLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEAP---WDSDD 2874 Query: 1045 PATTSSEATTTPRPLLSTPVDGAEDPRCLEALKPGNCGEYVVRWYYDKQVNS---CARFW 1101 P S P+D G+C Y +RWY+ S C F Sbjct: 2875 PC--------------SLPLD------------EGSCTAYTLRWYHRAVTGSTEACHPFV 2908 Query: 1102 FSGCNGSGNRFNSEKECQETC 1122 + GC G+ NRF + + C+ C Sbjct: 2909 YGGCGGNANRFGTREACERRC 2929 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 448 bits (1152), Expect = e-125 Identities = 268/600 (44%), Positives = 308/600 (51%), Gaps = 94/600 (15%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 + G PG PGPPG G G+ G GPKG G + G+AGERG G PG G G+ GE G Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAG--EPGKAGERGVPGPPGAVGPAGKDGEAGA 618 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQ 361 G G G G G +GP G G G PG GP G G GE G PG G+PG G G+ Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678 Query: 362 QGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE----GF 407 +G GERG +G PG GP G G+ G PG G +G PG +G+PGE G Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738 Query: 408 PGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP-- 465 PGPKG++G GP G G G G +G GP+GP GP G PG +GE G GP GP Sbjct: 739 PGPKGDRGDAGPKGADGSPGKD--GVRGLTGPIGPPGPAGAPG--DKGESGPSGPAGPTG 794 Query: 466 ----------PGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGS 508 PGP GPAG G PG+KGE G G G GP G GP G PG Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA--GPAGPPGP 852 Query: 509 IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKGSKGNQGQ 564 IG G PG G G+AG G G PGA G GPPG G PGP G GK+G KG +G+ Sbjct: 853 IGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGE 912 Query: 565 RGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQG 624 G P G PG +GP PGPPGP G++G PG G G PG GP+G+ G Sbjct: 913 TG------PAGRPGEVGP--------PGPPGPAGEKGSPGADGPAGAPGTP--GPQGIAG 956 Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG 682 RG VG PG +G+ G+PG+PGP G PG GP G G G G G PG+ GPPG SG G Sbjct: 957 QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG 1016 Query: 683 V----------GTQGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPG 722 G+ G KGD G+ G GPPG PG G G +GE GP G G Sbjct: 1017 APGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAG 1076 Query: 723 PKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIG---EPGSPGKQGLQGPKGDLG 772 P G +G G G KGE GE+GD G KG +G G PG PG G QGP G G Sbjct: 1077 PVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASG 1136 Score = 444 bits (1142), Expect = e-124 Identities = 265/571 (46%), Positives = 311/571 (54%), Gaps = 64/571 (11%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G G PGPPG PG +G +GP G PG + G +G GP G PG G G+ GE GKPG Sbjct: 185 GPRGLPGPPGA---PGPQGFQGPPGEPG--EPGASGPMGPRGPPGPPGKNGDDGEAGKPG 239 Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360 G++G PGP G +G G G+ G G G G G KG+ GP GP G PG+PG G Sbjct: 240 RPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPG 299 Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGP 419 Q G +G G+ GRPGAPGP G G G G GP G G G P GFPG G KG GP Sbjct: 300 QMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP--GFPGAVGAKGEAGP 357 Query: 420 TGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPG 478 GP+G +G ++GE G GP G GP G P G+ G+ G +G G PG G G PG Sbjct: 358 QGPRGSEGPQGVRGEPGPPGPAGAAGPAGNP--GADGQPGAKGANGAPGIAG--APGFPG 413 Query: 479 SKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 ++G G GP GP GP G G G KGEPG +G+ G PG GE+G G +G Sbjct: 414 ARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG 473 Query: 529 EAGLPGARGPEGPPG-KGQPGPK---GDEGKKGSKGNQGQRGLPGPEGPKGEPGIM---G 581 E PG G GPPG +G PG + G +G G KG G+RG PGP GPKG PG G Sbjct: 474 E---PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPG 530 Query: 582 PFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG- 636 G+PG T PG PGP G G PG G G PG GP G +G G +G PG KG Sbjct: 531 EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP--GPPGARGQAGVMGFPGPKGA 588 Query: 637 DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQK 695 G PG G RG+PGPPG VG G GE G +GPPGP+GP G G QGP G G + Sbjct: 589 AGEPGKAGERGVPGPPG-----AVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643 Query: 696 GLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHGER 741 GLPGP GPPG G QG+ G+ +G +GFPG +G G G G +G +G Sbjct: 644 GLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAP 703 Query: 742 GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G+ G KGD G G PGS G GLQG G+ G Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERG 734 Score = 380 bits (976), Expect = e-105 Identities = 240/518 (46%), Positives = 272/518 (52%), Gaps = 56/518 (10%) Query: 244 KGDPGDPGPPGTHGNPGIKG---ERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299 KGD G PG PG+ G PG++G ERG G PG +G+AG +G G PG G +G G Sbjct: 709 KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768 Query: 300 CGKPG---IKGDKGSPGPYGPKGP---RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353 G PG GDKG GP GP GP RG G G PG PGP GF G G G PG G Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGE 828 Query: 354 PGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPK 411 PG G +G G G G G PGPIG VG PG G RG G PG G PG G GP Sbjct: 829 PG--DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886 Query: 412 GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGP 471 G G+ GP GP G G++G GP G GP G P G +GPPGP GP Sbjct: 887 GPSGNAGPPGPPG-----PAGKEGGKGPRGETGPAGRP-----------GEVGPPGPPGP 930 Query: 472 AGQ-GLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 AG+ G PG+ G G G GP+G G +G+ G +GE G GLPG G PG+ G +G Sbjct: 931 AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGA 990 Query: 527 KGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGM 585 GE G P GP GPPG G PG G EG G++G+ G+ G PG +G +GE G GP G Sbjct: 991 SGERGPP---GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047 Query: 586 PGT-SIPGPPGP---KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD-GY 639 PG PGP GP GDRG G G G G + RGP G QGPRG G G +GD G Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107 Query: 640 PGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLP 698 G G GL GPPGP G G G +GA G G RGPPG +G G G GLP Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG--------KDGLNGLP 1159 Query: 699 GPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736 GP GPP G +G G+ GP G PGP G G P G Sbjct: 1160 GPIGPP--GPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 293 bits (749), Expect = 8e-79 Identities = 179/398 (44%), Positives = 210/398 (52%), Gaps = 50/398 (12%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGD-------- 293 ++G+PG PGP G G PG G+ G KG PG+A KG+AG GP G G G Sbjct: 801 DRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPG 860 Query: 294 -KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP---PG 349 KG RG G PG G G+ G GP GP G G GPPG G +G +G +GE GP PG Sbjct: 861 AKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPG 920 Query: 350 PYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERG 401 G PG PG G++G G G G PG PGP G VG PGQ G RG G+PG G Sbjct: 921 EVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSG 980 Query: 402 LPGEGFP-GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGI 459 PG+ P G GE+G GP GP GL G GE G G G +G G G G++G++G Sbjct: 981 EPGKQGPSGASGERGPPGPMGPPGLAGPP--GESGREGAPGAEGSPGRDGSPGAKGDRGE 1038 Query: 460 QGPIGPPG---------PQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEP 506 GP GPPG P GPAG+ G +GE G GP GP GPVG G QGP+G+ Sbjct: 1039 TGPAGPPGAPGAPGAPGPVGPAGKS--GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDK 1096 Query: 507 GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566 G G G G+ G G +G +G G PG+ G +GP G GP G G GS G G+ G Sbjct: 1097 GETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGAS--GPAGPRGPPGSAGAPGKDG 1154 Query: 567 LP------GPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598 L GP GP+G G GP G PG PGPPGP G Sbjct: 1155 LNGLPGPIGPPGPRGRTGDAGPVGPPGP--PGPPGPPG 1190 Score = 289 bits (739), Expect = 1e-77 Identities = 177/406 (43%), Positives = 203/406 (50%), Gaps = 50/406 (12%) Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463 EG P GSE PT + ++G KGD GP GP+GP G PG G G+ G+ GP Sbjct: 88 EGECCPVCPDGSESPTDQETT---GVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPP 144 Query: 464 GPPGPQGPAGQGLPGSKGEVGQMGPT-----GPRGPVGIGVQGPKGEPGSIGLPGQPGVP 518 GPPGP GP G G G P + GI V GP G G GLPG PG P Sbjct: 145 GPPGPPGPPGLG--------GNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196 Query: 519 GEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEP 577 G G G GE G PGA GP GP G G PG GD+G+ G G G+RG PGP+G +G P Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256 Query: 578 GIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVG 630 G G GM G G GP G +G PG PG G PG GP+G+ G RG G Sbjct: 257 GTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQM--GPRGLPGERGRPG 314 Query: 631 APGLKG----DGYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPG 676 APG G DG G GP G GP GP G G G G++G GVRG PG Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374 Query: 677 PSGPRGV-------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728 P GP G G G G G G PG G PG+ G++G G QGP G PGPKG G Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434 Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G PG KG+ G +G+ G G +G G G GK+G +G G GL Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480 Score = 281 bits (719), Expect = 2e-75 Identities = 168/367 (45%), Positives = 191/367 (52%), Gaps = 23/367 (6%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 KG G GPPG G PG G GP G GNA G G GP G G KG +GE G G+P Sbjct: 862 KGARGSAGPPGATGFPGAAGRVGPPGPSGNA--GPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI---- 359 G G G PGP G KG G G G PG PGP+G G +G G PG G G PG+ Sbjct: 920 GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPS 979 Query: 360 GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGSE 417 G+ G +G G G G PGP+G G G PG G EG PG G PG +G PG KG++G Sbjct: 980 GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039 Query: 418 GPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476 GP GP G G G GPVGP G G G G G GP+GP G +GPAG QG Sbjct: 1040 GPAGPPG-----APGAPGAPGPVGPAGKSG--DRGETGPAGPAGPVGPVGARGPAGPQGP 1092 Query: 477 PGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGA 535 G KGE G+ G G +G G G+QGP G PGS PG+ G G G AG +G G GA Sbjct: 1093 RGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGS---PGEQGPSGASGPAGPRGPPGSAGA 1149 Query: 536 RGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPG 595 G +G G PGP G G +G G+ G G PGP GP G PG G + +P PP Sbjct: 1150 PGKDGL--NGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA-GFDFSFLPQPPQ 1206 Query: 596 PKGDRGG 602 K GG Sbjct: 1207 EKAHDGG 1213 Score = 147 bits (371), Expect = 6e-35 Identities = 101/243 (41%), Positives = 112/243 (46%), Gaps = 43/243 (17%) Query: 565 RGLPGPEGPKGE------PGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPGLS 615 + PG E P+GE G P T + GP G P+G RG G PG G PG Sbjct: 79 KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP 138 Query: 616 IRGPKGVQGPRGPVGAPGLKGDGYP--------------------GVPGPRGLPGPPGPM 655 G G GP GP G PGL G+ P G GPRGLPGPPG Sbjct: 139 --GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196 Query: 656 GLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKG 713 G +G G G GEPG GP GP GP G G G G+ G+ G PG GPPG QG +G Sbjct: 197 GPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPG--PQGARG 254 Query: 714 EQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G G PG KG G G G +GD G G KGE PGSPG+ G G G GL Sbjct: 255 LPGTAGLPGMKGHRGFS-----GLDGAKGDAGPAGPKGE---PGSPGENGAPGQMGPRGL 306 Query: 774 TKE 776 E Sbjct: 307 PGE 309 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 447 bits (1150), Expect = e-125 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%) Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299 GD G PGPPG G PG KGE+G +G PG K G+ GE G GIPG GD G GE Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346 G+ G KG KG GP GP G PR GIT G PG+ G +GF G +G PG Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398 PGP G+ PG PG G +G++G EG PG PGP G+ G+PG PG GP G G Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449 P + PGP G GS G G QG QG +KG+KGD G GP G G+P Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491 G+ G +G+ G GP G PG P P G PGSKGE G + G G Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538 +G +G G+ G G PG GLPG PG GE G KGE G LPG GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590 GPPG G PGP G++G +G GN GQ G+PGP+G G+ PG G G PG + Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637 PG PG G G PGIPG KGEPG+ GPKG G GP GAPG G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690 G PG PGP+G LPGPPGP GL G G G KG+ G GPPGP G G+ G GPKG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739 D G G PGP GPPG G++G GP G PGP G G HG+PG+KG+ G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859 Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773 ERG G G G IG PGSP G G G KG++G+ Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900 Score = 441 bits (1135), Expect = e-123 Identities = 271/597 (45%), Positives = 317/597 (53%), Gaps = 80/597 (13%) Query: 244 KGDPGD--PGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGEC 300 KG+PG PGPPG G PG KG GPKG+ G G G G G+PG KGD G G+ Sbjct: 748 KGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQP 807 Query: 301 GKPG--------IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF--------QGNKGE 344 G G ++G G PG GP G G+ GI G GDPGP G +G+ G Sbjct: 808 GPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGI 867 Query: 345 PGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGV 396 PG PGP G PG+PG+ G G KGE G G PG PGP+G+ G G PG +G +G+ Sbjct: 868 PGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGL 927 Query: 397 PGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIG------PVGPQGPMGIP 449 G+ GLPG G G KGE G GP GP L KGEKG+ G GP+G G+P Sbjct: 928 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987 Query: 450 GIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507 G G+ G+ G G PGP GP G GLPG G +G G G G +G G QG +G PG Sbjct: 988 G--DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045 Query: 508 SIGLPGQPGVPGEDGAAGKKGEAG-----LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ 562 G+PGQPG PG G G KG+ G LPG GP+G PG PG G+ G KGS G+ Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL--PGYPGNPGIKGSVGDP 1103 Query: 563 GQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG--------- 613 G GLPG G KG+PG+ G PGT PGPPGPKG G PG PG GEPG Sbjct: 1104 GLPGLPGTPGAKGQPGLPG---FPGT--PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158 Query: 614 -------LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------ 660 G G+ GP G G PG G G PG PG GL G G GL G+ Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218 Query: 661 ----GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQG 716 G+ G G PGV+GPPGP G G +GPKG+ G +G PG PGP G+ QG+ G +G Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGF--QGLPGPEG 1276 Query: 717 PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 P G PG G G G G+ G G G KGD+G G G+PG+ GL G KGD GL Sbjct: 1277 PPGLPGNGGIKGE--KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGL 1331 Score = 434 bits (1117), Expect = e-121 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%) Query: 238 KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295 +ICE PG PGPPG+ G+ G++GE+G KG+ G+ G GP G PG G G Sbjct: 449 EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351 G G PG KG+KG G GPKG GI G G PG PG KG G+ G G G Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405 GSPGAPG+ G+ G GQ+G PG PGP GEPG G RGP G PG GLPG Sbjct: 564 GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 406 ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439 G PGP GEKG +G G P+G G +I G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 440 VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491 G G G PG+ GS+GE GI G IG PGP GP G G PG+ G G++G GP Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738 Query: 492 RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548 GP G GPKGEPG G PG PG+PG GA G KG+ G PG GP G G G PG Sbjct: 739 PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796 Query: 549 PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595 PKGD G G G G GLPG +GP G PGI GP G PG PGPPG Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856 Query: 596 -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630 P G+RG PGIPG G PGL +G G+ GP GP G Sbjct: 857 GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916 Query: 631 -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676 PGLKGD G PG+PGP G LPGPPGPM +G G KGEPG+ G PG Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 677 PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722 SGP+G G G G +GQ GLPGPPGP G G G+KG G GFPG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 723 PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749 P+G G GLPG KGE G G G G Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096 Query: 750 KGEIGEPGSPGKQGLQGPKGDLGL 773 KG +G+PG PG G G KG GL Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120 Score = 434 bits (1115), Expect = e-121 Identities = 286/658 (43%), Positives = 339/658 (51%), Gaps = 113/658 (17%) Query: 243 EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284 EKGDPG PG PPG G+PGI G GP G PG+ KGE G GP Sbjct: 844 EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903 Query: 285 ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318 G+PG KGD G +G+ G PG G+KGS PGP GP K Sbjct: 904 PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963 Query: 319 GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378 G +G G+ G PG GPKG+QG G+PG PG G PG PG G KG G G+PG G Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021 Query: 379 PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422 P G +G+ G PGP+G EG PG G+PG+ G PG KG+KG G + GP Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 423 QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473 +G GL G G G VG G G+PG G++G+ G+ G G PGP GP G Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 474 QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524 GLPG G VG Q GP G +G G G+ GP G+ G G PG PG PG G + Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201 Query: 525 GKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583 G+KG+ GLPG G G PG KG+PG G G +G G G G P EGPKG PG GP Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPP 1260 Query: 584 GMPGTS----IPGPPGP---------KGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPV 629 G PG + +PGP GP KG++G PG PG G PGL +GP G+QG G Sbjct: 1261 GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRP 1320 Query: 630 GAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP- 688 G G+KGD PG+PG G PG GP G+ G G +GEPG+ GPPGP G G Q Sbjct: 1321 GLNGMKGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSII 1376 Query: 689 -KGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGD 743 KGD G G+PG PG +G+ G QGPQG PGP G G +GLPG G G +GD Sbjct: 1377 IKGDAGPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGD 1431 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799 G G G G G PG GLQGP G G + LIT P+C + L++ Sbjct: 1432 PGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1489 Score = 418 bits (1075), Expect = e-116 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291 G PG PG PG G PG G GP+G PG N KGE G GP GIPG K Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155 Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336 G+ KG G G PGI+ G G PGP GP GP G+ G GPPG PGPK Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215 Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377 G FQG KGE G G G PG PG G QG+ G+RG G PG Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275 Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419 GP G GE G+PG RG G GE G PG G PG GEKG +G Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450 TGP G GL + GEKG+ G G QGP G+PG Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494 G GE+G +G GPPG P GL G G G GP GP GP Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455 Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525 +G G+ GP G+P GLPG PG PG G G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512 Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574 +KGE G GA GP+G PG G PG KG+ G G KG++G+ G PG G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627 G PG G G+PG +PGP G KG+RG PG PG G PG + GP G GP G Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629 Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669 PVG G++G G PG+PGP+G PG PG GL G GD G G+P Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725 G+ G PG G G+G GP G G G+PGPPG PG G G++G GP GFPGPKG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772 G LPG G G +G +G KGD+G G PG PG+ GL GPKGD+G Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Score = 411 bits (1056), Expect = e-114 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%) Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296 C+C KG+ G+ G PG G+PG+ G GP+G PG QKG+ G GP G G +G G Sbjct: 38 CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG+ G G G GP+G G G G G PG GF G +G PGPP Sbjct: 98 PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415 G G+KGE G PGP G PG PGP G +G+PG G+PG G PGP G G Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461 GP GP+G GL+ +G KG+ G G QGP G PG S+ G+QG+ G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519 GPPGP G G P G KGE G+ G G RG G G G+PG GLPG PG PG Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322 Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574 E G G+KG+ G G GP G PG G G KG+ G G G +G+RG PG +GP Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381 Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 PG+ GP PG ++ GPPGP G G G G +G PG+SI GP G+ G G G PG Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692 G P +P + PGPPGP G GD G +GE GV+G G + +GT G G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493 Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744 GQ GLPG PGPPG G G KGE+G G GPKG G G PG G GE GD+ Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553 Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G KGDKGE+G PG+PG GL G G GL Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Score = 301 bits (772), Expect = 2e-81 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%) Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409 YG GIKGE+G+ G PG G PG PG GPEG PG RG G+ G PG Sbjct: 30 YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84 Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468 P G KG GP G G G G G G G GP GIPG G++GE+G G G PG Sbjct: 85 PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527 QGP G G+PG KGE G + + + GPKG PG G PG G+PG G G Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570 G G PG GP GPPG PGPKG+ +G KG KG QG +G PGP Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626 +G +G PG GP G PG I GPPGP G G G G +GEPG RG G G Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306 Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674 G G PGL GD GYPG PG +G GPPGP GL G G T G KG G+ G Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728 PG G RG G QGP G G G + GPPGPPG+ G +G KG++GP G PGP G G Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 G PG G G G D EI EPG PG G GD GL E+ +K Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474 Score = 172 bits (435), Expect = 2e-42 Identities = 104/233 (44%), Positives = 124/233 (53%), Gaps = 23/233 (9%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 E KG+PG GPPG G G +G GP+G PG G GGI G KG+ G+ G Sbjct: 1248 EGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP--------GNGGIKGEKGNPGQPGLP 1299 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIG 360 G PG+KGD+G PG G G G+ G+ G PG PG GF G KG G PG G G PG+ Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGL- 1358 Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 G G PG PGP G + G GP G+PG+ GL G PGP+G +G GPT Sbjct: 1359 -------IGPPGPPGLPGPSGQSIIIK-GDAGPPGIPGQPGLKG--LPGPQGPQGLPGPT 1408 Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473 GP G G + G G G G +G G+P G G +G+ GP GP G QGP G Sbjct: 1409 GPPGDPGRN--GLPGFDGAGGRKGDPGLP--GQPGTRGLDGPPGPDGLQGPPG 1457 Score = 76.3 bits (186), Expect = 2e-13 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%) Query: 239 ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 I + + G PG PG PG G P G +GP+G PG G G+ G G+PG+ G G +G Sbjct: 1376 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1430 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331 + PG+ G G+ G GP GP G+QG GPPG Sbjct: 1431 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 447 bits (1150), Expect = e-125 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%) Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299 GD G PGPPG G PG KGE+G +G PG K G+ GE G GIPG GD G GE Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346 G+ G KG KG GP GP G PR GIT G PG+ G +GF G +G PG Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398 PGP G+ PG PG G +G++G EG PG PGP G+ G+PG PG GP G G Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449 P + PGP G GS G G QG QG +KG+KGD G GP G G+P Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491 G+ G +G+ G GP G PG P P G PGSKGE G + G G Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538 +G +G G+ G G PG GLPG PG GE G KGE G LPG GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590 GPPG G PGP G++G +G GN GQ G+PGP+G G+ PG G G PG + Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637 PG PG G G PGIPG KGEPG+ GPKG G GP GAPG G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690 G PG PGP+G LPGPPGP GL G G G KG+ G GPPGP G G+ G GPKG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739 D G G PGP GPPG G++G GP G PGP G G HG+PG+KG+ G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859 Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773 ERG G G G IG PGSP G G G KG++G+ Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900 Score = 440 bits (1131), Expect = e-123 Identities = 277/608 (45%), Positives = 321/608 (52%), Gaps = 93/608 (15%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG-----ERGPGGIPGYKGDKGER 297 KG PG PGPPG G PG G GP G PG KGE G GP G+PG+KG G Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP- 773 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-----PYG 352 KGD+G PGP GP G G+ G+ GP GD GP G G G PG PG P G Sbjct: 774 --------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825 Query: 353 SPGAPG-IGQQGIKGERGQEGRPGAPG------PIGVGEPGQPGPRGPEGVPGERGLPGE 405 PG PG IGQ G+ G G++G PG PG P G PG PG GP G PG GLPG+ Sbjct: 826 PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885 Query: 406 ----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQ 460 GFPG KGE G GP GP G L I G G G G G G PG+ G GE+G + Sbjct: 886 AGASGFPGTKGEMGMMGPPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 461 GPIGPPGPQGPAGQGLPGSKGEVGQMG------PTGPRGPVGI-------------GVQG 501 G G PGP GP L GSKGE G+ G +GP+G G+ G+ G Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 P G G+ GLPGQPG+ G G G G+ G PG +G EGPPG GQPG G G+KG Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 558 SKGNQG--QRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGF 608 KG+ G GLPG GPKGEPG+ G G PG +PG PG G +G PG+PGF Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123 Query: 609 KGEPGLSIRGPKGVQGPRGPVGAPG----LKGDGYPGVPGPRGLPGPPGPMGLRGVGDTG 664 G PG GPKG+ GP G G PG + G G+PG PGP G G PG G+ G G Sbjct: 1124 PGTPGPP--GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG--PAG 1179 Query: 665 AKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-------YGSQGIKGE--- 714 KGEPG G P P G G KGD G G+PG PG PG +G G++G Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 715 --------QGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765 +GP+G PGP+G G GLPG +G G G+ G KG+KG G+PG PG GL+ Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK 1299 Query: 766 GPKGDLGL 773 G +G GL Sbjct: 1300 GDQGPPGL 1307 Score = 437 bits (1124), Expect = e-122 Identities = 285/653 (43%), Positives = 341/653 (52%), Gaps = 109/653 (16%) Query: 243 EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284 EKGDPG PG PPG G+PGI G GP G PG+ KGE G GP Sbjct: 844 EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903 Query: 285 ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318 G+PG KGD G +G+ G PG G+KGS PGP GP K Sbjct: 904 PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963 Query: 319 GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378 G +G G+ G PG GPKG+QG G+PG PG G PG PG G KG G G+PG G Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021 Query: 379 PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422 P G +G+ G PGP+G EG PG G+PG+ G PG KG+KG G + GP Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 423 QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473 +G GL G G G VG G G+PG G++G+ G+ G G PGP GP G Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 474 QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524 GLPG G VG Q GP G +G G G+ GP G+ G G PG PG PG G + Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201 Query: 525 GKKGEAGLPGARG------PEGPPG-KGQPGPKGDEGKKGSKGN--QGQRGLPGPEGPKG 575 G+KG+ GLPG G P+G PG G PG +G G GS G +G +G PGP+GP G Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPG 1261 Query: 576 EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGL 634 PG+ GP G PG +PG G KG++G PG PG G PGL +GP G+QG G G G+ Sbjct: 1262 RPGLPGPEGPPG--LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM 1319 Query: 635 KGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP--KGDT 692 KGD PG+PG G PG GP G+ G G +GEPG+ GPPGP G G Q KGD Sbjct: 1320 KGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1375 Query: 693 GQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKG 748 G G+PG PG +G+ G QGPQG PGP G G +GLPG G G +GD G G Sbjct: 1376 GPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPG 1430 Query: 749 DKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799 G G G PG GLQGP G G + LIT P+C + L++ Sbjct: 1431 QPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1483 Score = 434 bits (1117), Expect = e-121 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%) Query: 238 KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295 +ICE PG PGPPG+ G+ G++GE+G KG+ G+ G GP G PG G G Sbjct: 449 EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351 G G PG KG+KG G GPKG GI G G PG PG KG G+ G G G Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405 GSPGAPG+ G+ G GQ+G PG PGP GEPG G RGP G PG GLPG Sbjct: 564 GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 406 ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439 G PGP GEKG +G G P+G G +I G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 440 VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491 G G G PG+ GS+GE GI G IG PGP GP G G PG+ G G++G GP Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738 Query: 492 RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548 GP G GPKGEPG G PG PG+PG GA G KG+ G PG GP G G G PG Sbjct: 739 PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796 Query: 549 PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595 PKGD G G G G GLPG +GP G PGI GP G PG PGPPG Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856 Query: 596 -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630 P G+RG PGIPG G PGL +G G+ GP GP G Sbjct: 857 GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916 Query: 631 -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676 PGLKGD G PG+PGP G LPGPPGPM +G G KGEPG+ G PG Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 677 PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722 SGP+G G G G +GQ GLPGPPGP G G G+KG G GFPG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 723 PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749 P+G G GLPG KGE G G G G Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096 Query: 750 KGEIGEPGSPGKQGLQGPKGDLGL 773 KG +G+PG PG G G KG GL Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120 Score = 418 bits (1075), Expect = e-116 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291 G PG PG PG G PG G GP+G PG N KGE G GP GIPG K Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155 Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336 G+ KG G G PGI+ G G PGP GP GP G+ G GPPG PGPK Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215 Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377 G FQG KGE G G G PG PG G QG+ G+RG G PG Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275 Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419 GP G GE G+PG RG G GE G PG G PG GEKG +G Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450 TGP G GL + GEKG+ G G QGP G+PG Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494 G GE+G +G GPPG P GL G G G GP GP GP Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455 Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525 +G G+ GP G+P GLPG PG PG G G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512 Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574 +KGE G GA GP+G PG G PG KG+ G G KG++G+ G PG G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627 G PG G G+PG +PGP G KG+RG PG PG G PG + GP G GP G Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629 Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669 PVG G++G G PG+PGP+G PG PG GL G GD G G+P Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725 G+ G PG G G+G GP G G G+PGPPG PG G G++G GP GFPGPKG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772 G LPG G G +G +G KGD+G G PG PG+ GL GPKGD+G Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Score = 411 bits (1056), Expect = e-114 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%) Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296 C+C KG+ G+ G PG G+PG+ G GP+G PG QKG+ G GP G G +G G Sbjct: 38 CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG+ G G G GP+G G G G G PG GF G +G PGPP Sbjct: 98 PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415 G G+KGE G PGP G PG PGP G +G+PG G+PG G PGP G G Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461 GP GP+G GL+ +G KG+ G G QGP G PG S+ G+QG+ G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519 GPPGP G G P G KGE G+ G G RG G G G+PG GLPG PG PG Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322 Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574 E G G+KG+ G G GP G PG G G KG+ G G G +G+RG PG +GP Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381 Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 PG+ GP PG ++ GPPGP G G G G +G PG+SI GP G+ G G G PG Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692 G P +P + PGPPGP G GD G +GE GV+G G + +GT G G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493 Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744 GQ GLPG PGPPG G G KGE+G G GPKG G G PG G GE GD+ Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553 Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G KGDKGE+G PG+PG GL G G GL Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Score = 301 bits (772), Expect = 2e-81 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%) Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409 YG GIKGE+G+ G PG G PG PG GPEG PG RG G+ G PG Sbjct: 30 YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84 Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468 P G KG GP G G G G G G G GP GIPG G++GE+G G G PG Sbjct: 85 PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527 QGP G G+PG KGE G + + + GPKG PG G PG G+PG G G Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570 G G PG GP GPPG PGPKG+ +G KG KG QG +G PGP Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626 +G +G PG GP G PG I GPPGP G G G G +GEPG RG G G Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306 Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674 G G PGL GD GYPG PG +G GPPGP GL G G T G KG G+ G Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728 PG G RG G QGP G G G + GPPGPPG+ G +G KG++GP G PGP G G Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 G PG G G G D EI EPG PG G GD GL E+ +K Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474 Score = 171 bits (432), Expect = 5e-42 Identities = 103/222 (46%), Positives = 118/222 (53%), Gaps = 21/222 (9%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 E KG+PG GPP G PG+ G GP G PGN G GE+G G PG G G +G+ Sbjct: 1248 EGPKGNPGPQGPP---GRPGLPGPEGPPGLPGNG--GIKGEKGNPGQPGLPGLPGLKGDQ 1302 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G PG++G+ G PG G KG G+ G+ G PG GP G G+ G G PG G PG PG+ Sbjct: 1303 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1362 Query: 360 GQQG----IKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPK 411 G G IKG+ G G PG PG G+ G G PGP GP G PG GLP GF G Sbjct: 1363 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GFDGAG 1420 Query: 412 GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453 G KG G G G +GL G GP G QGP G PG S Sbjct: 1421 GRKGDPGLPGQPGTRGLD-----GPPGPDGLQGPPGPPGTSS 1457 Score = 76.3 bits (186), Expect = 2e-13 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%) Query: 239 ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 I + + G PG PG PG G P G +GP+G PG G G+ G G+PG+ G G +G Sbjct: 1370 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1424 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331 + PG+ G G+ G GP GP G+QG GPPG Sbjct: 1425 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 447 bits (1150), Expect = e-125 Identities = 290/641 (45%), Positives = 333/641 (51%), Gaps = 116/641 (18%) Query: 245 GDPGDPGPPGTHGNPGI----KGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGE 299 GD G PGPPG G PG KGE+G +G PG K G+ GE G GIPG GD G GE Sbjct: 264 GDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGE 323 Query: 300 CGKPGIKGDKGSPGPYGPKG---PRGIQGIT----------GPPGDPGPKGFQGNKGEPG 346 G+ G KG KG GP GP G PR GIT G PG+ G +GF G +G PG Sbjct: 324 PGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPG 383 Query: 347 PPGPYGS-----PGAPGIGQQGIKGERGQEGRPGA--PGPIGV-GEPGQPGPRGPEGVPG 398 PGP G+ PG PG G +G++G EG PG PGP G+ G+PG PG GP G G Sbjct: 384 LPGPPGAAVMGPPGPPGF--PGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG 441 Query: 399 ERGLPGEGF--PGPKGEKGSEGPTGPQGLQGLSIKGEKGDI-------GPVGPQGPMGIP 449 P + PGP G GS G G QG QG +KG+KGD G GP G G+P Sbjct: 442 PHIPPSDEICEPGPPGPPGSPGDKGLQGEQG--VKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 450 GI-------------GSQGEQGIQGPIGPPG-PQGPAGQGLPGSKGEVGQM----GPTGP 491 G+ G +G+ G GP G PG P P G PGSKGE G + G G Sbjct: 500 GLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD 559 Query: 492 RGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG---------LPGARGP 538 +G +G G+ G G PG GLPG PG GE G KGE G LPG GP Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 539 EGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE----PGIMGPFGMPG----TSI 590 GPPG G PGP G++G +G GN GQ G+PGP+G G+ PG G G PG + Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 591 PGPPGPKGDRGGPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGLKG-------D 637 PG PG G G PGIPG KGEPG+ GPKG G GP GAPG G Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPP 739 Query: 638 GYPGVPGPRG-----LPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690 G PG PGP+G LPGPPGP GL G G G KG+ G GPPGP G G+ G GPKG Sbjct: 740 GPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG---------- 739 D G G PGP GPPG G++G GP G PGP G G HG+PG+KG+ G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPP 859 Query: 740 -ERGDVGKKGDKGEIGEPGSP------GKQGLQGPKGDLGL 773 ERG G G G IG PGSP G G G KG++G+ Sbjct: 860 GERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGM 900 Score = 440 bits (1131), Expect = e-123 Identities = 296/651 (45%), Positives = 327/651 (50%), Gaps = 136/651 (20%) Query: 244 KGDPG------DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG-------PG--GIP 288 KG+PG + GPPG G PG+ G GP G PG G GE+G PG GIP Sbjct: 590 KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIP 649 Query: 289 GYKGDKGER----------------------------GECGKPGIKGDKGSPGPYG---- 316 G KGD G+ G+ G PGI G KG PG G Sbjct: 650 GPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLP 709 Query: 317 -PKGPRGIQGITGPPG------------DPGPKGFQGNKGEPG--PPGPYGSPGAPGI-G 360 P GP+G GI GPPG PGP GF G KGEPG PGP G PG PG G Sbjct: 710 GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769 Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERG---LPGEGFPGPKGEKGS 416 G KG+RG G PG PG G+ G PG G GP G PG G LPG G GP G G Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829 Query: 417 EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ- 474 GP G GL G I GEKGD GP G P G PG GS G G GPIGPPG G G+ Sbjct: 830 PGPIGQPGLHG--IPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKA 886 Query: 475 ---GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEA 530 G PG+KGE+G MGP GP GP+GI G G G G GL GQPG+PG G G KGE Sbjct: 887 GASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEP 946 Query: 531 GLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS- 589 GLPG GP P G KG KG G G+PG GPKG G+ G G PG S Sbjct: 947 GLPGPPGPMDP---------NLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSG 997 Query: 590 ---IPGPPGPKGDRGGPGIPGFKGEPGLS-------IRGPKGVQGPRGPVGAPGL----- 634 +PGPPGPKG+ G PG PG G PGL GP+GV+GP GP G PG Sbjct: 998 QPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPG 1057 Query: 635 -------KGD------GYPGVPGPRG---LPGPPGPMGLRG-VGDTG---------AKGE 668 KGD G PG+PGP+G LPG PG G++G VGD G AKG+ Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117 Query: 669 PGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGP 723 PG+ G PG GP G G GP G+ G G PGP G G+ G G KG+ G G PGP Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGP 1177 Query: 724 KGTMGHGLPGQKG--EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G PGQ G G G G G KG+ G PG PG GL GPKG+ G Sbjct: 1178 AGQKGE--PGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPG 1226 Score = 436 bits (1121), Expect = e-122 Identities = 277/611 (45%), Positives = 316/611 (51%), Gaps = 96/611 (15%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG-----ERGPGGIPGYKGDKGER 297 KG PG PGPPG G PG G GP G PG KGE G GP G+PG+KG G Sbjct: 715 KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP- 773 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG-----PYG 352 KGD+G PGP GP G G+ G+ GP GD GP G G G PG PG P G Sbjct: 774 --------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPG 825 Query: 353 SPGAPG-IGQQGIKGERGQEGRPGAPG------PIGVGEPGQPGPRGPEGVPGERGLPGE 405 PG PG IGQ G+ G G++G PG PG P G PG PG GP G PG GLPG+ Sbjct: 826 PPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGK 885 Query: 406 ----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQ 460 GFPG KGE G GP GP G L I G G G G G G PG+ G GE+G + Sbjct: 886 AGASGFPGTKGEMGMMGPPGPPG--PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSK 943 Query: 461 GPIGPPGPQGPAGQGLPGSKGEVGQMG------PTGPRGPVGI-------------GVQG 501 G G PGP GP L GSKGE G+ G +GP+G G+ G+ G Sbjct: 944 GEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG 1003 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 P G G+ GLPGQPG+ G G G G+ G PG +G EGPPG GQPG G G+KG Sbjct: 1004 PPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKG 1063 Query: 558 SKGNQG--QRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGF 608 KG+ G GLPG GPKGEPG+ G G PG +PG PG G +G PG+PGF Sbjct: 1064 DKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGF 1123 Query: 609 KGEPGLSIRGPKGVQGPRGPVGAPG----LKGDGYPGVPGPRGLPGPPGPMGLRGVGDTG 664 G PG GPKG+ GP G G PG + G G+PG PGP G G PG G+ G G Sbjct: 1124 PGTPGPP--GPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPG--PAG 1179 Query: 665 AKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGP 723 KGEPG G P P G G KGD G G+PG PG PG G G G G QG PGP Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 724 KGTMG---------------------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 G+ G GLPG +G G G+ G KG+KG G+PG PG Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1299 Query: 763 GLQGPKGDLGL 773 GL+G +G GL Sbjct: 1300 GLKGDQGPPGL 1310 Score = 434 bits (1117), Expect = e-121 Identities = 296/684 (43%), Positives = 333/684 (48%), Gaps = 160/684 (23%) Query: 238 KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKG--EAGERGPGGIPGYKGDKG 295 +ICE PG PGPPG+ G+ G++GE+G KG+ G+ G GP G PG G G Sbjct: 449 EICE-----PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGN----KGEPGPPGPY 351 G G PG KG+KG G GPKG GI G G PG PG KG G+ G G G Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQ---PGPRGPEGVPGERGLPGE--- 405 GSPGAPG+ G+ G GQ+G PG PGP GEPG G RGP G PG GLPG Sbjct: 564 GSPGAPGL--PGLPGTPGQDGLPGLPGP--KGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 406 ------GFPGPKGEKGSEGPTG---------PQGLQGLSIK-----------GEKGDIGP 439 G PGP GEKG +G G P+G G +I G GD+G Sbjct: 620 MGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL 679 Query: 440 VGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMGPTGP 491 G G G PG+ GS+GE GI G IG PGP GP G G PG+ G G++G GP Sbjct: 680 PGDPGLPGQPGLPGIPGSKGEPGIPG-IGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738 Query: 492 RGPVGIGVQGPKGEPGSI--GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPG 548 GP G GPKGEPG G PG PG+PG GA G KG+ G PG GP G G G PG Sbjct: 739 PGPPGF--PGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPG 796 Query: 549 PKGDEGKKGSKGNQGQRGLPG--PEGPKGEPGIMGPFGMPGT-------SIPGPPG---- 595 PKGD G G G G GLPG +GP G PGI GP G PG PGPPG Sbjct: 797 PKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVP 856 Query: 596 -PKGDRGGPGIPGFKG------EPGL----------SIRGPKGVQGPRGPVG-------- 630 P G+RG PGIPG G PGL +G G+ GP GP G Sbjct: 857 GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916 Query: 631 -APGLKGD----GYPGVPGPRG---------LPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676 PGLKGD G PG+PGP G LPGPPGPM +G G KGEPG+ G PG Sbjct: 917 GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976 Query: 677 PSGPRGV----GTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQGFPG 722 SGP+G G G G +GQ GLPGPPGP G G G+KG G GFPG Sbjct: 977 VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036 Query: 723 PKGTMGH---------------------------------GLPGQKGEHGERGDVGKKGD 749 P+G G GLPG KGE G G G G Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096 Query: 750 KGEIGEPGSPGKQGLQGPKGDLGL 773 KG +G+PG PG G G KG GL Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGL 1120 Score = 434 bits (1117), Expect = e-121 Identities = 286/655 (43%), Positives = 338/655 (51%), Gaps = 110/655 (16%) Query: 243 EKGDPGDPG-----PPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGP 284 EKGDPG PG PPG G+PGI G GP G PG+ KGE G GP Sbjct: 844 EKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP 903 Query: 285 ------------GGIPGYKGDKGERGECGKPGIKGDKGS------PGPYGP--------K 318 G+PG KGD G +G+ G PG G+KGS PGP GP K Sbjct: 904 PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK 963 Query: 319 GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG 378 G +G G+ G PG GPKG+QG G+PG PG G PG PG G KG G G+PG G Sbjct: 964 GEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPG--PPGPKGNPGLPGQPGLIG 1021 Query: 379 PIG----VGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPT--------GP 422 P G +G+ G PGP+G EG PG G+PG+ G PG KG+KG G + GP Sbjct: 1022 PPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGP 1081 Query: 423 QGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG------- 473 +G GL G G G VG G G+PG G++G+ G+ G G PGP GP G Sbjct: 1082 KGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN 1141 Query: 474 QGLPGSKGEVG------QMGPTGPRGPVGI-GVQGPKGEPGSIGLPG--QPGVPGEDGAA 524 GLPG G VG Q GP G +G G G+ GP G+ G G PG PG PG G + Sbjct: 1142 PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLS 1201 Query: 525 GKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583 G+KG+ GLPG G G PG KG+PG G G +G G G G P EGPKG PG GP Sbjct: 1202 GQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPP 1260 Query: 584 GMPG-TSIPGPPGP---------KGDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAP 632 G PG +PGP GP KG++G PG PG G PGL +GP G+QG G G Sbjct: 1261 GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLN 1320 Query: 633 GLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGP--KG 690 G+KGD PG+PG G PG GP G+ G G +GEPG+ GPPGP G G Q KG Sbjct: 1321 GMKGD--PGLPGVPGFPGMKGPSGVPG--SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1376 Query: 691 DTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGK 746 D G G+PG PG +G+ G QGPQG PGP G G +GLPG G G +GD G Sbjct: 1377 DAGPPGIPGQPG-----LKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGL 1431 Query: 747 KGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC--GPKCKETPLEL 799 G G G G PG GLQGP G G + LIT P+C + L++ Sbjct: 1432 PGQPGTRGLDGPPGPDGLQGPPGPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQV 1486 Score = 418 bits (1075), Expect = e-116 Identities = 290/713 (40%), Positives = 331/713 (46%), Gaps = 191/713 (26%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAG------------ERGPGGIPGYK 291 G PG PG PG G PG G GP+G PG N KGE G GP GIPG K Sbjct: 96 GLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMK 155 Query: 292 GD------------KGERGECGKPGIK---GDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336 G+ KG G G PGI+ G G PGP GP GP G+ G GPPG PGPK Sbjct: 156 GEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPK 215 Query: 337 G-----FQGNKGEPGPPGPYGSPGAPG--------------IGQQGIKGERGQEGRPGAP 377 G FQG KGE G G G PG PG G QG+ G+RG G PG Sbjct: 216 GNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIR 275 Query: 378 GPIG--------VGEPGQPGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGP 419 GP G GE G+PG RG G GE G PG G PG GEKG +G Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGD 335 Query: 420 TGPQGLQGL--------------------SIKGEKGDIGPVGPQGPMGIPG--------- 450 TGP G GL + GEKG+ G G QGP G+PG Sbjct: 336 TGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGP 395 Query: 451 ---IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP------------- 494 G GE+G +G GPPG P GL G G G GP GP GP Sbjct: 396 PGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455 Query: 495 -----------------------------VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525 +G G+ GP G+P GLPG PG PG G G Sbjct: 456 PGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQP---GLPGLPGPPGSLGFPG 512 Query: 526 KKGEAGLPGARGPEGPPG-------KGQPGPKGDEGK----KGSKGNQGQRGLPGPEGPK 574 +KGE G GA GP+G PG G PG KG+ G G KG++G+ G PG G Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 575 GEPGIMGPFGMPGTSIPGPPGP------KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRG 627 G PG G G+PG +PGP G KG+RG PG PG G PG + GP G GP G Sbjct: 573 GLPGTPGQDGLPG--LPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPG 629 Query: 628 PVGAPGLKG----DGYPGVPGPRGLPG----PPGPMGLRG----------VGDTGAKGEP 669 PVG G++G G PG+PGP+G PG PG GL G GD G G+P Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 670 GVRGPPGPSGP---RGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725 G+ G PG G G+G GP G G G+PGPPG PG G G++G GP GFPGPKG Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 726 TMGHGLPGQKGE---HGERGDVGKKGDKGEIGEPGSPGK---QGLQGPKGDLG 772 G LPG G G +G +G KGD+G G PG PG+ GL GPKGD+G Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVG 802 Score = 411 bits (1056), Expect = e-114 Identities = 258/570 (45%), Positives = 304/570 (53%), Gaps = 60/570 (10%) Query: 240 CECE--KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGE 296 C+C KG+ G+ G PG G+PG+ G GP+G PG QKG+ G GP G G +G G Sbjct: 38 CDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGL 97 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG+ G G G GP+G G G G G PG GF G +G PGPP Sbjct: 98 PGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPP-------- 149 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415 G G+KGE G PGP G PG PGP G +G+PG G+PG G PGP G G Sbjct: 150 ---GIPGMKGEPGSIIMSSLPGP--KGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMG 204 Query: 416 SEGP---TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQ-----------GEQGIQG 461 GP GP+G GL+ +G KG+ G G QGP G PG S+ G+QG+ G Sbjct: 205 PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPG 264 Query: 462 PIGPPGPQGPAGQGLP--GSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPG 519 GPPGP G G P G KGE G+ G G RG G G G+PG GLPG PG PG Sbjct: 265 DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKP--GKDGENGQPGIPGLPGDPGYPG 322 Query: 520 EDGAAGKKGEAGLPGARGPEG----PPGKG-QPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574 E G G+KG+ G G GP G PG G G KG+ G G G +G+RG PG +GP Sbjct: 323 EPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGP- 381 Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 PG+ GP PG ++ GPPGP G G G G +G PG+SI GP G+ G G G PG Sbjct: 382 --PGLPGP---PGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGP 436 Query: 635 KGDGYPGVPGPRGL--PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDT 692 G P +P + PGPPGP G GD G +GE GV+G G + +GT G G Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPG--SPGDKGLQGEQGVKGDKGDTCFNCIGT-GISGPP 493 Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDV--- 744 GQ GLPG PGPPG G G KGE+G G GPKG G G PG G GE GD+ Sbjct: 494 GQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF 553 Query: 745 -GKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G KGDKGE+G PG+PG GL G G GL Sbjct: 554 PGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Score = 301 bits (772), Expect = 2e-81 Identities = 214/473 (45%), Positives = 240/473 (50%), Gaps = 71/473 (15%) Query: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPG 409 YG GIKGE+G+ G PG G PG PG GPEG PG RG G+ G PG Sbjct: 30 YGCSPGSKCDCSGIKGEKGERGFPGLEG-----HPGLPGFPGPEGPPGPRGQKGDDGIPG 84 Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGP 468 P G KG GP G G G G G G G GP GIPG G++GE+G G G PG Sbjct: 85 PPGPKGIRGPPGLPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGL 142 Query: 469 QGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527 QGP G G+PG KGE G + + + GPKG PG G PG G+PG G G Sbjct: 143 QGPPGPPGIPGMKGEPGSI--------IMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPI 194 Query: 528 GEAGLPGARGPEGPPGKGQPGPKGD-----EGKKGSKGNQGQRGLPGP------------ 570 G G PG GP GPPG PGPKG+ +G KG KG QG +G PGP Sbjct: 195 GPPGPPGLMGPPGPPGL--PGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPID 252 Query: 571 ----EGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626 +G +G PG GP G PG I GPPGP G G G G +GEPG RG G G Sbjct: 253 VEFQKGDQGLPGDRGPPGPPG--IRGPPGPPG--GEKGEKGEQGEPGK--RGKPGKDGEN 306 Query: 627 GPVGAPGLKGD-GYPGVPG------PRGLPGPPGPMGL----RGVGDT-GAKGEPGVRGP 674 G G PGL GD GYPG PG +G GPPGP GL G G T G KG G+ G Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366 Query: 675 PGPSGPRGV-GTQGPKGDTGQKG--LPGPPGPPGY-GSQGIKGEQGPQGF--PGPKGTMG 728 PG G RG G QGP G G G + GPPGPPG+ G +G KG++GP G PGP G G Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 729 H-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 G PG G G G D EI EPG PG G GD GL E+ +K Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSD--EICEPGPPGPPG---SPGDKGLQGEQGVK 474 Score = 173 bits (438), Expect = 9e-43 Identities = 103/222 (46%), Positives = 118/222 (53%), Gaps = 18/222 (8%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 E KG+PG GPPG G G+ G GP G PGN G GE+G G PG G G +G+ Sbjct: 1248 EGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNG--GIKGEKGNPGQPGLPGLPGLKGDQ 1305 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G PG++G+ G PG G KG G+ G+ G PG GP G G+ G G PG G PG PG+ Sbjct: 1306 GPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLP 1365 Query: 360 GQQG----IKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPK 411 G G IKG+ G G PG PG G+ G G PGP GP G PG GLP GF G Sbjct: 1366 GPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP--GFDGAG 1423 Query: 412 GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453 G KG G G G +GL G GP G QGP G PG S Sbjct: 1424 GRKGDPGLPGQPGTRGLD-----GPPGPDGLQGPPGPPGTSS 1460 Score = 76.3 bits (186), Expect = 2e-13 Identities = 41/93 (44%), Positives = 53/93 (56%), Gaps = 8/93 (8%) Query: 239 ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 I + + G PG PG PG G P G +GP+G PG G G+ G G+PG+ G G +G Sbjct: 1373 IIKGDAGPPGIPGQPGLKGLP---GPQGPQGLPG--PTGPPGDPGRNGLPGFDGAGGRKG 1427 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG 331 + PG+ G G+ G GP GP G+QG GPPG Sbjct: 1428 D---PGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 446 bits (1148), Expect = e-125 Identities = 273/648 (42%), Positives = 335/648 (51%), Gaps = 129/648 (19%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGG------------I 287 +G+PG+PG PG G G +G GP G PG+ + G+AGERGP G + Sbjct: 224 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 283 Query: 288 PGYKGDKG------ERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGP 335 PG KG +G +GE G PG+KG+ GSP GP GP+G G +G TGP G G Sbjct: 284 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 343 Query: 336 KGFQGNKGEPGPPGPYGSPGAPGI----------------GQQGIKGERGQEGRPGAPGP 379 +G G G GPPGP G G PG G +G +G RG+ G PG+PGP Sbjct: 344 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 403 Query: 380 IGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQG-------L 428 G G G PG +G G PG G P GFPGP+G G +G TGP G +G Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAP--GFPGPRGPPGPQGATGPLGPKGQTGEPGIA 461 Query: 429 SIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQG-PAGQGLPGSK 480 KGE+G G GP GP G PG G++GE G GPIGPPG +G P +G PG Sbjct: 462 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 521 Query: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 G G G G RGP G+ GPKG G G PG+PG+PG G G+ G+AG G GP G Sbjct: 522 GLAGPKGAPGERGPSGLA--GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 579 Query: 541 PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG------------ 587 PG+ G+PGP G + G++G G G PGP+G GEPG G G+PG Sbjct: 580 APGEDGRPGPPGPQ---GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636 Query: 588 -TSIPGPPGP------KGDRGGPGIPGFKGEPG----------------LSIRGPKGVQG 624 T GPPGP +G++G PG GF+G PG G G+ G Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696 Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSG 679 PRG G PG +G G G+ GPRGLPG PG G +G G GA+G PG++G PG G Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756 Query: 680 PRGV-GTQGPKGDTGQK------------GLPGPPGPPG-YGSQGIKGEQGPQGFPGPKG 725 G+ G +G +GD G+K GL GP GPPG G+ G KGE GP PGP G Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP---PGPAG 813 Query: 726 TMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 + G G PG++GE G G G G G G+PG+ G+QG G KGD G Sbjct: 814 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 861 Score = 442 bits (1137), Expect = e-124 Identities = 286/643 (44%), Positives = 335/643 (52%), Gaps = 95/643 (14%) Query: 213 LLSDPTLVDKIQDRL--DILFEKKCERKICECEKGDP-GDPGPPGTHGNPG-IKGERGPK 268 +L D + + ++D L +I F + C IC + G PGP G G PG IK GPK Sbjct: 62 VLCDDIICEDVKDCLSPEIPFGECCP--ICPTDLATASGQPGPKGQKGEPGDIKDIVGPK 119 Query: 269 GNPGNAQKGEAGERGPGGIPGYKGDKGE---RGECGKPGIKGDKGSPGPYGPKGPRGIQG 325 G PG +G AGE+GP G G KG+KG RG G+PG G+ G PGP GP GP G+ G Sbjct: 120 GPPG--PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGG 177 Query: 326 ---------------------ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQQG 363 + GP G GP+G G G PGP G G+PG PG G G Sbjct: 178 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSG 237 Query: 364 IKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTG 421 G RG G PG PG G G+PG+ G RGP G G RG PG G PG KG +G G G Sbjct: 238 PMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG 297 Query: 422 PQGLQGL-SIKGEKG---DIGPVGPQGPMGIPG----------IGSQGEQGIQGPIGPPG 467 +G G +KGE G + G GP GP G+PG G++G G GP GPPG Sbjct: 298 AKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPG 357 Query: 468 PQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGV---PGEDGA 523 P GPAG G PG+ G G+ GPTG RGP G QGP+GEPG+ G PG G PG DG Sbjct: 358 PVGPAGGPGFPGAPGAKGEAGPTGARGPEG--AQGPRGEPGTPGSPGPAGASGNPGTDGI 415 Query: 524 AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPG---PEGPKGEPGI 579 G KG AG PG G G PG +G PGP+G G G KG G+ G+ G +GPKGEPG Sbjct: 416 PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGP 475 Query: 580 MGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPR 626 GP G PG + GP GP G+RG PG GF G+ GL+ GPKG G R Sbjct: 476 AGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLA--GPKGAPGER 533 Query: 627 GPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPS 678 GP G G KG G PG+PG RGL G PG G +G VG +GA GE G GPPGP Sbjct: 534 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593 Query: 679 GPRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPG 733 G RG +G GPKG G+ G G G PG G +G+ G+ G G GP PG Sbjct: 594 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGP--------PG 645 Query: 734 QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 G GERG+ G G G G PG PG G G GD G+ E Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGE 688 Score = 439 bits (1128), Expect = e-123 Identities = 282/682 (41%), Positives = 337/682 (49%), Gaps = 155/682 (22%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERG-PG--GIPGYKGD 293 KG+PG GP G G G +G+RG +G PG ++G G RG PG G+ G KG Sbjct: 470 KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 529 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG------FQGNKGEPGP 347 GERG G G KG G PG G G G +G+TG PGD GP+G G G PGP Sbjct: 530 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589 Query: 348 PGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGP 393 PGP G+ G PG+ G G G+ G++G PGAPG G+ G G PGP GP Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649 Query: 394 EGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLS-------------IKGEKGD 436 G GE+G PG +G PGP G G G G QG+ G + GE+G Sbjct: 650 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 709 Query: 437 IGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494 G G QGP G+PG G+ G +G GP GPPG QGP G QG+PG +G G GP G RG Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769 Query: 495 VG-------------------IGVQGP---KGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532 VG IG GP GE G +G PG G G GA G++GE G Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 829 Query: 533 PGARGPEGPPGK-GQPGPKGDEGKKGSKGN------QGQRGLPGPEGPKGE--------- 576 PG G GPPG GQPG KG++G+ G KG+ QG G PGP+GP G Sbjct: 830 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 889 Query: 577 ---------PGIMGPFGMPGTS----IPGPPGP------KGDRGGPGIPGFKGEPGLS-- 615 PG G G PG++ PGPPGP KG RG G PG GEPGL Sbjct: 890 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949 Query: 616 -----------IRGPKGVQGPRGP---------VGAPGLKGD-GYPGVPGPRGLPG---- 650 GP G +GP GP VG PG +G+ G+PG+PGP G PG Sbjct: 950 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 651 --------PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLP 698 PPGP+G G+ TG GEPG G PG GP G G +G +G+TG G P Sbjct: 1010 PGASGDRGPPGPVGPPGL--TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 1067 Query: 699 GPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK 750 G PGPPG G QG +GE G QG GP G G G+ G +G G++G+ G+ G++ Sbjct: 1068 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1127 Query: 751 GEIGEPGSPGKQGLQGPKGDLG 772 G G G G QGL GP G G Sbjct: 1128 GLKGHRGFTGLQGLPGPPGPSG 1149 Score = 435 bits (1119), Expect = e-121 Identities = 283/648 (43%), Positives = 321/648 (49%), Gaps = 129/648 (19%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG---DKGERGE 299 E G PG PGP G G PG+ G GPKG N + G+AGE+G G PG +G GE G Sbjct: 583 EDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 640 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG------PYGS 353 G PG G G G G GP G QG+ GPPG PG G G++G PG G P G Sbjct: 641 AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 700 Query: 354 PGAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG- 404 G PG G QG++G RG G PG GP G G PG GP G +G+PGERG G Sbjct: 701 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 760 Query: 405 ---------------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449 EG PG G +G GP GP G G + GEKG++GP GP G G Sbjct: 761 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN--GEKGEVGPPGPAGSAGAR 818 Query: 450 GI-GSQGEQGIQGPIG---PPGPQGPAG----QGLPGSKGEVGQMGPTGP------RGPV 495 G G +GE G GP G PPG G G QG G KG+ G GP GP +GP Sbjct: 819 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 878 Query: 496 GI-------GVQGPKGE------------PGSIGLPGQPGVPGEDGAAGKKG-------- 528 G+ G QGP G PGS G PG PG PG G G KG Sbjct: 879 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938 Query: 529 -EAGLPGARGPEGPPG-KGQPG---PKGDEGKKGSKGNQGQRG---LPGPEGPKGEPGIM 580 AG PG +GP GPPG KG+PG P G EG G +G GQRG LPG G +G PG+ Sbjct: 939 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPG------IPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 GP G PG G PG GDRG PG + G GEPG G G GP G GA G+ Sbjct: 999 GPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGRE--GSPGADGPPGRDGAAGV 1054 Query: 635 KGD-------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQ 686 KGD G PG PGP G PGP GP G +G D G G G GP GP+G RG+ G Q Sbjct: 1055 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGAQGPMGPSGPAGARGIQGPQ 1112 Query: 687 GPKGD------------------TGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727 GP+GD TG +GLPGPPGP G G+ G G GP+G PGP G Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1172 Query: 728 G----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 G +G+PG G G RG G+ G G G PG PG G GP D+ Sbjct: 1173 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1220 Score = 434 bits (1115), Expect = e-121 Identities = 258/587 (43%), Positives = 311/587 (52%), Gaps = 70/587 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301 E G PG+ G PG G G+ GERG G G A +G G+ GP G PG G G G G Sbjct: 310 ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 369 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360 PG KG+ G G GP+G +G +G G PG PGP G GN G G PG GS GAPGI G Sbjct: 370 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 429 Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 G G RG G GA GP+ G GQ G G G GE+G GE PGP G +G+ GP Sbjct: 430 APGFPGPRGPPGPQGATGPL--GPKGQTGEPGIAGFKGEQGPKGE--PGPAGPQGAPGPA 485 Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG------ 473 G +G +G +GE G +GP+GP G G PG G G+ G+ GP G PG +GP+G Sbjct: 486 GEEGKRG--ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543 Query: 474 ----------QGLPGSKGEVGQMGPTGPRGPVG-------------IGVQGPKGEPGSIG 510 GLPG++G G+ G GP+G VG G QG +G+PG +G Sbjct: 544 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 603 Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQG 563 PG G GE G AG+KG G PG RG G G+ G GP G+ G++G+ G G Sbjct: 604 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663 Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQ 623 +GLPGP GP GE G G G+PG + G PG G RG G PG +G P G +G+Q Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGVPGEA--GAPGLVGPRGERGFPGERGSP-----GAQGLQ 716 Query: 624 GPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672 GPRG G PG G G PG GP GL G PG G G+ GD G GE G Sbjct: 717 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 776 Query: 673 GPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727 G PG G RG +G GP G G+KG GPPGP G G++G GE+G G PGP G Sbjct: 777 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 836 Query: 728 GHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G PG G+ G +G+ G+ G KG+ G PG G G GP+G G+T Sbjct: 837 GP--PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 881 Score = 429 bits (1103), Expect = e-120 Identities = 271/592 (45%), Positives = 314/592 (53%), Gaps = 67/592 (11%) Query: 244 KGDPGDPGPPGTHGNPGI---KGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 +G G GP G G PGI KGE+GPKG PG A G G GP G G +G +GE G Sbjct: 443 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGV 500 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G G G++G+PG G G G+ G G PG+ GP G G KG G PG G PG PG Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 360 ------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPG---ER 400 G+ G G G++GRPG PGP G G+PG PGP+G G PG E+ Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620 Query: 401 GLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG---PMGIPGIGS 453 GLPG G PG GE G+ GP GP G G +GE+G GP G QG P G PG G Sbjct: 621 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGG 678 Query: 454 Q-GEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKG 504 + G+QG+ G G PG GP G+ G PG +G G G GPRG G G GP G Sbjct: 679 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 738 Query: 505 EPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 PG+ G PG G+PGE GAAG KG+ G G +GPEG PGK G GP G G G Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 798 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSI 616 + G +G+ G PGP G G G G G G PGP G G G G PG KGE G Sbjct: 799 ANGEKGEVGPPGPAGSAGARGAPGERGETGP--PGPAGFAGPPGADGQPGAKGEQGEAGQ 856 Query: 617 RGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGV 671 +G G GP+GP GAPG +G G G G RG GPPG G G VG G+ G PG Sbjct: 857 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916 Query: 672 RGPPGPSG---PRGV-GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGT 726 GPPGPSG P+G G GP G G+ GL GP GPPG G G G G +G PGP+G Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976 Query: 727 MGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G GLPGQ+GE G G G G+ G+ G PG+ G +G GP G GLT Sbjct: 977 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028 Score = 424 bits (1091), Expect = e-118 Identities = 268/633 (42%), Positives = 312/633 (49%), Gaps = 118/633 (18%) Query: 243 EKGDPGDPGP------PGTHGNPGIKGERGPKGNPG----------------------NA 274 +KG+ G PGP PGT GNPG G GP G PG Sbjct: 139 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 198 Query: 275 QKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG 334 +G G GP G PG G G +G G PG G+ G GP GP+GP G G G G+ G Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258 Query: 335 PKGFQGNKGEPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPG 386 G G +G PGP G G PG PG+ G G+ G +G+ G PG G G GE G Sbjct: 259 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 318 Query: 387 QPGPRGPEGVPGERG----------------------------LPGEGFPGPKGEKGSEG 418 PGP GP G+PGERG G GFPG G KG G Sbjct: 319 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 378 Query: 419 PTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQG 470 PTG +G +G +GE G G GP G G PG GS G GI G G PGP+G Sbjct: 379 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438 Query: 471 PAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 P PG +G G +GP G G GI G QGPKGEPG G G PG GE+G G Sbjct: 439 P-----PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 493 Query: 527 KGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 +GE PG GP GPPG +G PG G G KG+ G +G GL GP+G G+PG Sbjct: 494 RGE---PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 550 Query: 580 MGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 G G+PG T PG GP+G G G PG G PG GP+G +G G +G PG K Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--GPQGARGQPGVMGFPGPK 608 Query: 636 G-DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693 G +G PG G +GLPG PG GL G GE G GPPGP+GP G G QG G +G Sbjct: 609 GANGEPGKAGEKGLPGAPGLRGL-----PGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 663 Query: 694 QKGLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHG 739 +GLPGPPGPPG G QG+ GE +G +GFPG +G+ G GL G +G G Sbjct: 664 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 723 Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G KG G G PG+ G GLQG G+ G Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756 Score = 294 bits (753), Expect = 3e-79 Identities = 194/464 (41%), Positives = 222/464 (47%), Gaps = 87/464 (18%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGE 299 EKG+ G PGP G+ G G GERG G PG A G AG G G PG KG++GE +G+ Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGPA--GFAGPPGADGQPGAKGEQGEAGQKGD 859 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG +G G+PGP GP G G +G G G PG GF G G GPPG G+PG PG Sbjct: 860 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 919 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE 405 G+ G KG RG G PG G G+ GEPG GP G EG PG +GL G+ Sbjct: 920 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 979 Query: 406 ----GFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGE 456 G PG +GE+G G GP G G G GD GP GP GP G+ G G +G Sbjct: 980 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 1039 Query: 457 QGIQGPIG------------------------PPGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 G GP G PPG GPAG G G +GE G GP GP Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099 Query: 492 RGPVGI-GVQGPKG---------EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541 GP G G+QGP+G EPG GL G G G G G G +G GA GP GP Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159 Query: 542 PG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEG---------PKGEPGIMGPFGMPGTSIP 591 G +G PGP G GK G+ G G G PGP G P G PG GP P Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP--------P 1211 Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 GPPGP G + F G G +GP +Q R A GL+ Sbjct: 1212 GPPGP-----GIDMSAFAG-LGPREKGPDPLQYMRADQAAGGLR 1249 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 446 bits (1148), Expect = e-125 Identities = 273/648 (42%), Positives = 335/648 (51%), Gaps = 129/648 (19%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGG------------I 287 +G+PG+PG PG G G +G GP G PG+ + G+AGERGP G + Sbjct: 155 QGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 214 Query: 288 PGYKGDKG------ERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGP 335 PG KG +G +GE G PG+KG+ GSP GP GP+G G +G TGP G G Sbjct: 215 PGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGA 274 Query: 336 KGFQGNKGEPGPPGPYGSPGAPGI----------------GQQGIKGERGQEGRPGAPGP 379 +G G G GPPGP G G PG G +G +G RG+ G PG+PGP Sbjct: 275 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGP 334 Query: 380 IGV----GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQG-------L 428 G G G PG +G G PG G P GFPGP+G G +G TGP G +G Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAP--GFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392 Query: 429 SIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGPIGPPGPQG-PAGQGLPGSK 480 KGE+G G GP GP G PG G++GE G GPIGPPG +G P +G PG Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452 Query: 481 GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 G G G G RGP G+ GPKG G G PG+PG+PG G G+ G+AG G GP G Sbjct: 453 GLAGPKGAPGERGPSGLA--GPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSG 510 Query: 541 PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG------------ 587 PG+ G+PGP G + G++G G G PGP+G GEPG G G+PG Sbjct: 511 APGEDGRPGPPGPQ---GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567 Query: 588 -TSIPGPPGP------KGDRGGPGIPGFKGEPG----------------LSIRGPKGVQG 624 T GPPGP +G++G PG GF+G PG G G+ G Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627 Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSG 679 PRG G PG +G G G+ GPRGLPG PG G +G G GA+G PG++G PG G Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687 Query: 680 PRGV-GTQGPKGDTGQK------------GLPGPPGPPG-YGSQGIKGEQGPQGFPGPKG 725 G+ G +G +GD G+K GL GP GPPG G+ G KGE GP PGP G Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP---PGPAG 744 Query: 726 TMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 + G G PG++GE G G G G G G+PG+ G+QG G KGD G Sbjct: 745 SAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAG 792 Score = 442 bits (1137), Expect = e-124 Identities = 278/614 (45%), Positives = 321/614 (52%), Gaps = 90/614 (14%) Query: 239 ICECEKGDPGDPGPPGTHGNPG-IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE- 296 + C+ D PGP G G PG IK GPKG PG +G AGE+GP G G KG+KG Sbjct: 20 VLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPG--PQGPAGEQGPRGDRGDKGEKGAP 77 Query: 297 --RGECGKPGIKGDKGSPGPYGPKGPRGIQG---------------------ITGPPGDP 333 RG G+PG G+ G PGP GP GP G+ G + GP G Sbjct: 78 GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM 137 Query: 334 GPKGFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPR 391 GP+G G G PGP G G+PG PG G G G RG G PG PG G G+PG+ G R Sbjct: 138 GPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 197 Query: 392 GPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKG---DIGPVGPQGPM 446 GP G G RG PG G PG KG +G G G +G G +KGE G + G GP GP Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPR 257 Query: 447 GIPG----------IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPV 495 G+PG G++G G GP GPPGP GPAG G PG+ G G+ GPTG RGP Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317 Query: 496 GIGVQGPKGEPGSIGLPGQPGV---PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKG 551 G QGP+GEPG+ G PG G PG DG G KG AG PG G G PG +G PGP+G Sbjct: 318 G--AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375 Query: 552 DEGKKGSKGNQGQRGLPG---PEGPKGEPGIMGPFGMPGTSIP-------------GPPG 595 G G KG G+ G+ G +GPKGEPG GP G PG + GP G Sbjct: 376 ATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG 435 Query: 596 PKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGL 648 P G+RG PG GF G+ GL+ GPKG G RGP G G KG G PG+PG RGL Sbjct: 436 PPGERGAPGNRGFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGL 493 Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGP 703 G PG G +G VG +GA GE G GPPGP G RG +G GPKG G+ G G G Sbjct: 494 TGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGL 553 Query: 704 PGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 PG G +G+ G+ G G GP PG G GERG+ G G G G PG PG Sbjct: 554 PGAPGLRGLPGKDGETGAAGP--------PGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605 Query: 763 GLQGPKGDLGLTKE 776 G G GD G+ E Sbjct: 606 GEGGKPGDQGVPGE 619 Score = 439 bits (1128), Expect = e-123 Identities = 282/682 (41%), Positives = 337/682 (49%), Gaps = 155/682 (22%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERG-PG--GIPGYKGD 293 KG+PG GP G G G +G+RG +G PG ++G G RG PG G+ G KG Sbjct: 401 KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGA 460 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG------FQGNKGEPGP 347 GERG G G KG G PG G G G +G+TG PGD GP+G G G PGP Sbjct: 461 PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520 Query: 348 PGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGP 393 PGP G+ G PG+ G G G+ G++G PGAPG G+ G G PGP GP Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580 Query: 394 EGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLS-------------IKGEKGD 436 G GE+G PG +G PGP G G G G QG+ G + GE+G Sbjct: 581 AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGS 640 Query: 437 IGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494 G G QGP G+PG G+ G +G GP GPPG QGP G QG+PG +G G GP G RG Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700 Query: 495 VG-------------------IGVQGP---KGEPGSIGLPGQPGVPGEDGAAGKKGEAGL 532 VG IG GP GE G +G PG G G GA G++GE G Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGP 760 Query: 533 PGARGPEGPPGK-GQPGPKGDEGKKGSKGN------QGQRGLPGPEGPKGE--------- 576 PG G GPPG GQPG KG++G+ G KG+ QG G PGP+GP G Sbjct: 761 PGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGA 820 Query: 577 ---------PGIMGPFGMPGTS----IPGPPGP------KGDRGGPGIPGFKGEPGLS-- 615 PG G G PG++ PGPPGP KG RG G PG GEPGL Sbjct: 821 QGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880 Query: 616 -----------IRGPKGVQGPRGP---------VGAPGLKGD-GYPGVPGPRGLPG---- 650 GP G +GP GP VG PG +G+ G+PG+PGP G PG Sbjct: 881 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 651 --------PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLP 698 PPGP+G G+ TG GEPG G PG GP G G +G +G+TG G P Sbjct: 941 PGASGDRGPPGPVGPPGL--TGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAP 998 Query: 699 GPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDK 750 G PGPPG G QG +GE G QG GP G G G+ G +G G++G+ G+ G++ Sbjct: 999 GAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGER 1058 Query: 751 GEIGEPGSPGKQGLQGPKGDLG 772 G G G G QGL GP G G Sbjct: 1059 GLKGHRGFTGLQGLPGPPGPSG 1080 Score = 435 bits (1119), Expect = e-121 Identities = 283/648 (43%), Positives = 321/648 (49%), Gaps = 129/648 (19%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG---DKGERGE 299 E G PG PGP G G PG+ G GPKG N + G+AGE+G G PG +G GE G Sbjct: 514 EDGRPGPPGPQGARGQPGVMGFPGPKG--ANGEPGKAGEKGLPGAPGLRGLPGKDGETGA 571 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG------PYGS 353 G PG G G G G GP G QG+ GPPG PG G G++G PG G P G Sbjct: 572 AGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGE 631 Query: 354 PGAPGI----GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG- 404 G PG G QG++G RG G PG GP G G PG GP G +G+PGERG G Sbjct: 632 RGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGI 691 Query: 405 ---------------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449 EG PG G +G GP GP G G + GEKG++GP GP G G Sbjct: 692 AGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN--GEKGEVGPPGPAGSAGAR 749 Query: 450 GI-GSQGEQGIQGPIG---PPGPQGPAG----QGLPGSKGEVGQMGPTGP------RGPV 495 G G +GE G GP G PPG G G QG G KG+ G GP GP +GP Sbjct: 750 GAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPT 809 Query: 496 GI-------GVQGPKGE------------PGSIGLPGQPGVPGEDGAAGKKG-------- 528 G+ G QGP G PGS G PG PG PG G G KG Sbjct: 810 GVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869 Query: 529 -EAGLPGARGPEGPPG-KGQPG---PKGDEGKKGSKGNQGQRG---LPGPEGPKGEPGIM 580 AG PG +GP GPPG KG+PG P G EG G +G GQRG LPG G +G PG+ Sbjct: 870 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPG------IPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 GP G PG G PG GDRG PG + G GEPG G G GP G GA G+ Sbjct: 930 GPSGEPGKQ--GAPGASGDRGPPGPVGPPGLTGPAGEPGRE--GSPGADGPPGRDGAAGV 985 Query: 635 KGD-------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQ 686 KGD G PG PGP G PGP GP G +G D G G G GP GP+G RG+ G Q Sbjct: 986 KGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG--DRGEAGAQGPMGPSGPAGARGIQGPQ 1043 Query: 687 GPKGD------------------TGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727 GP+GD TG +GLPGPPGP G G+ G G GP+G PGP G Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPS 1103 Query: 728 G----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 G +G+PG G G RG G+ G G G PG PG G GP D+ Sbjct: 1104 GKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDM 1151 Score = 434 bits (1115), Expect = e-121 Identities = 258/587 (43%), Positives = 311/587 (52%), Gaps = 70/587 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301 E G PG+ G PG G G+ GERG G G A +G G+ GP G PG G G G G Sbjct: 241 ESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPG 300 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360 PG KG+ G G GP+G +G +G G PG PGP G GN G G PG GS GAPGI G Sbjct: 301 APGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG 360 Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 G G RG G GA GP+ G GQ G G G GE+G GE PGP G +G+ GP Sbjct: 361 APGFPGPRGPPGPQGATGPL--GPKGQTGEPGIAGFKGEQGPKGE--PGPAGPQGAPGPA 416 Query: 421 GPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG------ 473 G +G +G +GE G +GP+GP G G PG G G+ G+ GP G PG +GP+G Sbjct: 417 GEEGKRG--ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474 Query: 474 ----------QGLPGSKGEVGQMGPTGPRGPVG-------------IGVQGPKGEPGSIG 510 GLPG++G G+ G GP+G VG G QG +G+PG +G Sbjct: 475 ANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMG 534 Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGKKGSKGNQG 563 PG G GE G AG+KG G PG RG G G+ G GP G+ G++G+ G G Sbjct: 535 FPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594 Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQ 623 +GLPGP GP GE G G G+PG + G PG G RG G PG +G P G +G+Q Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGVPGEA--GAPGLVGPRGERGFPGERGSP-----GAQGLQ 647 Query: 624 GPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672 GPRG G PG G G PG GP GL G PG G G+ GD G GE G Sbjct: 648 GPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPE 707 Query: 673 GPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTM 727 G PG G RG +G GP G G+KG GPPGP G G++G GE+G G PGP G Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFA 767 Query: 728 GHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G PG G+ G +G+ G+ G KG+ G PG G G GP+G G+T Sbjct: 768 GP--PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVT 812 Score = 429 bits (1103), Expect = e-120 Identities = 271/592 (45%), Positives = 314/592 (53%), Gaps = 67/592 (11%) Query: 244 KGDPGDPGPPGTHGNPGI---KGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 +G G GP G G PGI KGE+GPKG PG A G G GP G G +G +GE G Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPA--GPQGAPGPAGEEGKRGARGEPGGV 431 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G G G++G+PG G G G+ G G PG+ GP G G KG G PG G PG PG Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 491 Query: 360 ------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPG---ER 400 G+ G G G++GRPG PGP G G+PG PGP+G G PG E+ Sbjct: 492 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 551 Query: 401 GLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG---PMGIPGIGS 453 GLPG G PG GE G+ GP GP G G +GE+G GP G QG P G PG G Sbjct: 552 GLPGAPGLRGLPGKDGETGAAGPPGPAGPAGE--RGEQGAPGPSGFQGLPGPPGPPGEGG 609 Query: 454 Q-GEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKG 504 + G+QG+ G G PG GP G+ G PG +G G G GPRG G G GP G Sbjct: 610 KPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAG 669 Query: 505 EPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 PG+ G PG G+PGE GAAG KG+ G G +GPEG PGK G GP G G G Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAG 729 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSI 616 + G +G+ G PGP G G G G G G PGP G G G G PG KGE G Sbjct: 730 ANGEKGEVGPPGPAGSAGARGAPGERGETGP--PGPAGFAGPPGADGQPGAKGEQGEAGQ 787 Query: 617 RGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGV 671 +G G GP+GP GAPG +G G G G RG GPPG G G VG G+ G PG Sbjct: 788 KGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847 Query: 672 RGPPGPSG---PRGV-GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGT 726 GPPGPSG P+G G GP G G+ GL GP GPPG G G G G +G PGP+G Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907 Query: 727 MGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G GLPGQ+GE G G G G+ G+ G PG+ G +G GP G GLT Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959 Score = 424 bits (1091), Expect = e-118 Identities = 268/633 (42%), Positives = 312/633 (49%), Gaps = 118/633 (18%) Query: 243 EKGDPGDPGP------PGTHGNPGIKGERGPKGNPG----------------------NA 274 +KG+ G PGP PGT GNPG G GP G PG Sbjct: 70 DKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGV 129 Query: 275 QKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG 334 +G G GP G PG G G +G G PG G+ G GP GP+GP G G G G+ G Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189 Query: 335 PKGFQGNKGEPGPPGPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPG 386 G G +G PGP G G PG PG+ G G+ G +G+ G PG G G GE G Sbjct: 190 KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENG 249 Query: 387 QPGPRGPEGVPGERG----------------------------LPGEGFPGPKGEKGSEG 418 PGP GP G+PGERG G GFPG G KG G Sbjct: 250 SPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG 309 Query: 419 PTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQG 470 PTG +G +G +GE G G GP G G PG GS G GI G G PGP+G Sbjct: 310 PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369 Query: 471 PAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 P PG +G G +GP G G GI G QGPKGEPG G G PG GE+G G Sbjct: 370 P-----PGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGA 424 Query: 527 KGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 +GE PG GP GPPG +G PG G G KG+ G +G GL GP+G G+PG Sbjct: 425 RGE---PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR 481 Query: 580 MGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 G G+PG T PG GP+G G G PG G PG GP+G +G G +G PG K Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPP--GPQGARGQPGVMGFPGPK 539 Query: 636 G-DGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693 G +G PG G +GLPG PG GL G GE G GPPGP+GP G G QG G +G Sbjct: 540 GANGEPGKAGEKGLPGAPGLRGL-----PGKDGETGAAGPPGPAGPAGERGEQGAPGPSG 594 Query: 694 QKGLPGPPGPPGY----GSQGIKGE---------QGPQGFPGPKGTMG-HGLPGQKGEHG 739 +GLPGPPGPPG G QG+ GE +G +GFPG +G+ G GL G +G G Sbjct: 595 FQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPG 654 Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G KG G G PG+ G GLQG G+ G Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687 Score = 416 bits (1069), Expect = e-116 Identities = 273/627 (43%), Positives = 309/627 (49%), Gaps = 151/627 (24%) Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP---KGPRGIQGITGPPGDPGPKGFQGNKGE 344 PG KG KGE G+ I G KG PGP GP +GPRG +G G G PGP+G G G Sbjct: 31 PGPKGQKGEPGDI--KDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88 Query: 345 PGPPGPYGSPGAPG----------------------------IGQQGIKGERGQEGRPGA 376 PG PGP G PG PG G G G RG G GA Sbjct: 89 PGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGA 148 Query: 377 PGPIGV----GEPGQP---GPRGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGL 428 PGP G GEPG+P GP GP G PG G PG +G G G+ G GP GPQG +G Sbjct: 149 PGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF 208 Query: 429 ----------------------------SIKGEK---GDIGPVGPQGPMGIPG------- 450 +KGE G+ G GP GP G+PG Sbjct: 209 PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGP 268 Query: 451 ---IGSQGEQGIQGPIGPPGPQGPA-GQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP 506 G++G G GP GPPGP GPA G G PG+ G G+ GPTG RGP G QGP+GEP Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE--GAQGPRGEP 326 Query: 507 GSIGLPGQPGV---PGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQ 562 G+ G PG G PG DG G KG AG PG G G PG +G PGP+G G G KG Sbjct: 327 GTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQT 386 Query: 563 GQRGL---PGPEGPKGEPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIP 606 G+ G+ G +GPKGEPG GP G PG + GP GP G+RG PG Sbjct: 387 GEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNR 446 Query: 607 GFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG 659 GF G+ GL+ GPKG G RGP G G KG G PG+PG RGL G PG G +G Sbjct: 447 GFPGQDGLA--GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG 504 Query: 660 -VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPK------GDTGQKGLPGPP------- 701 VG +GA GE G GPPGP G RG +G GPK G G+KGLPG P Sbjct: 505 KVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG 564 Query: 702 --------GPPG-------YGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGD-- 743 GPPG G QG G G QG PGP G G G PG +G GE G Sbjct: 565 KDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPG 624 Query: 744 -VGKKGDKGEIGEPGSPGKQGLQGPKG 769 VG +G++G GE GSPG QGLQGP+G Sbjct: 625 LVGPRGERGFPGERGSPGAQGLQGPRG 651 Score = 294 bits (753), Expect = 3e-79 Identities = 194/464 (41%), Positives = 222/464 (47%), Gaps = 87/464 (18%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGE 299 EKG+ G PGP G+ G G GERG G PG A G AG G G PG KG++GE +G+ Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGPA--GFAGPPGADGQPGAKGEQGEAGQKGD 790 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG +G G+PGP GP G G +G G G PG GF G G GPPG G+PG PG Sbjct: 791 AGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGP 850 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIGV----------GEPGQPGPRGPEGVPGERGLPGE 405 G+ G KG RG G PG G G+ GEPG GP G EG PG +GL G+ Sbjct: 851 PGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ 910 Query: 406 ----GFPGPKGEKGSEGPTGPQGLQGLS-IKGEKGDIGPVGPQGPMGIPGI----GSQGE 456 G PG +GE+G G GP G G G GD GP GP GP G+ G G +G Sbjct: 911 RGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS 970 Query: 457 QGIQGPIG------------------------PPGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 G GP G PPG GPAG G G +GE G GP GP Sbjct: 971 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030 Query: 492 RGPVGI-GVQGPKG---------EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541 GP G G+QGP+G EPG GL G G G G G G +G GA GP GP Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090 Query: 542 PG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEG---------PKGEPGIMGPFGMPGTSIP 591 G +G PGP G GK G+ G G G PGP G P G PG GP P Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP--------P 1142 Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 GPPGP G + F G G +GP +Q R A GL+ Sbjct: 1143 GPPGP-----GIDMSAFAG-LGPREKGPDPLQYMRADQAAGGLR 1180 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 446 bits (1148), Expect = e-125 Identities = 271/596 (45%), Positives = 320/596 (53%), Gaps = 76/596 (12%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGK 302 +G PG PG PG G+ G KG GPKG G KGEAG GP G G G +G GE G+ Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346 Query: 303 ------PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPG------------PKGFQGNKGE 344 PG +G G PG GP GP GI G +G PG+PG P+G QG +GE Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406 Query: 345 PGPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402 GPPGP GSPG PG IG G G +G G PG GP G G PG PGP+G G G RG Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466 Query: 403 PGE-GFPGPKGEKGSEGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPG- 450 PG+ G PG KGE G +G GP G+QG +G+ G +GP GP G G PG Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526 Query: 451 IGSQGEQGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPVGI----GVQGPKGE 505 G G G+ GP G G +GP G P GS+G+ G+ G G G G+ GVQGP+G+ Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586 Query: 506 PGSIGLPGQ---PGVPGEDGAAGKKGEAGLPGARGPEGPPGK-------GQPGPKGDEGK 555 G +G PG+ PG PG G G+ G GLPG +G G PGK G PG +G GK Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK 646 Query: 556 KGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-- 613 G G G G PG G +GE G GP G G +PGPPGP G+ G PG G G+PG Sbjct: 647 DGEVGPSGPVGPPGLAGERGEQGPPGPTGFQG--LPGPPGPPGEGGKPGDQGVPGDPGAV 704 Query: 614 --LSIRGPKGVQGPRGPVGAPGLKG----------DGYPGVPGPRGLPGPPGPMGLRGVG 661 L RG +G G RG G GL G DG G PGP G PG GP GL+G+ Sbjct: 705 GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM- 763 Query: 662 DTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQG 716 GE G+ G PGP G RG G +G G+ G +GLPGP GPPG G G KGE G Sbjct: 764 ----PGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPG 819 Query: 717 PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 P+G GP G+ G+ PG +GE+G G VG G +G G+PG G+ G G KGD G Sbjct: 820 PRGLVGPPGSRGN--PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAG 873 Score = 438 bits (1126), Expect = e-122 Identities = 268/579 (46%), Positives = 307/579 (53%), Gaps = 64/579 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301 E+G+ G PGP G G PG G G G PG+ G+ G GP G G +G+ GERGE G Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---PGPPGPYGSPGAPG 358 G+ G+KG G +GP GP+G G +G PGD GP G QG GE G PGP G G G Sbjct: 724 ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG--G 781 Query: 359 IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPGE-GFPGP 410 IG++G +G G +G G PGP+G GE G+PGPRG G PG RG PG G GP Sbjct: 782 IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGP 841 Query: 411 KGEKGSEGPTGPQGLQGLSIK----GEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPP 466 G G GP GP G G+ + G+KGD G GPQG G PG G G+ G G Sbjct: 842 TGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG--PHGPNGVPGLKGGR 899 Query: 467 GPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAG 525 G QGP G G PGS G VG GP G GP G P GEPG G PG G PG G G Sbjct: 900 GTQGPPGATGFPGSAGRVGPPGPAGAPGPAG-----PLGEPGKEGPPGLRGDPGSHGRVG 954 Query: 526 KKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFG 584 +G AG PG G +G PG+ GQPGP G G G+ G +G G+PG G +G PG+ GP G Sbjct: 955 DRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG 1014 Query: 585 MPG----TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637 PG T G GP G G PG G GEPG GP G G G GA G +GD Sbjct: 1015 TPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE--GPAGNDGTPGRDGAVGERGDRGD 1072 Query: 638 -GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP------------PGPSGPRG-V 683 G G+PG +G PG PGP+G GD G +G+PG RGP PGP GPRG Sbjct: 1073 PGPAGLPGSQGAPGTPGPVG--APGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDK 1130 Query: 684 GTQGPKGDTGQKG---------LPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPG 733 G G +GD GQKG LPGPPGP G GS GI G GP+G PGP G G G Sbjct: 1131 GDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGK--EG 1188 Query: 734 QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G G G +G GE G G PG+ G GP G G Sbjct: 1189 NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227 Score = 437 bits (1123), Expect = e-122 Identities = 271/604 (44%), Positives = 320/604 (52%), Gaps = 82/604 (13%) Query: 245 GDPGDPGPPGTHGNPGIKGERG---PKGNPGNAQK----GEAGERGPGGIPGYKGDKGER 297 G+PG PG G GNPG++G G P G PG + G G RG G G G KG Sbjct: 564 GEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 G+ GKPG G+ G PG G G G G +GP G PG G +G +G PGP G G PG P Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 358 GI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGV---PGERGLPGEGFPGPKG 412 G G+ G G++G G PGA GP+G GE G PG RG G+ PGE+G+ G GP G Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGH--GPDG 741 Query: 413 EKGSEGP------TGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGI 459 KGS GP TGP GLQG+ GE+G G GP+G G G G+ G +G+ Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMP--GERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 460 QGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGS 508 GP+GPPGP GP G+ G PGS+G G G GP G VG G QGP G+PG Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGV 859 Query: 509 IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGN 561 G PG+PG G+ G+ G +G AG PG GP G PG +G PG G G G G Sbjct: 860 KGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGP 919 Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG---PGIPGFKGEPGLSIR- 617 G G PGP GP GEPG GP G+ G PG G GDRG PG PG KG+PG + Sbjct: 920 PGPAGAPGPAGPLGEPGKEGPPGLRGD--PGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977 Query: 618 ------GPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEP 669 GP G G RG VG PG +G+ G PG+PGP G PG GP G G G G G P Sbjct: 978 GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037 Query: 670 GVRGP---PGPSGPRG----------VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQ 715 G GP PGP GP G VG +G +GD G GLPG G PG G G G+ Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097 Query: 716 GPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768 G +G PG +G +G GLPG +G G++GD G +GD+G+ G G G QGL GP Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157 Query: 769 GDLG 772 G G Sbjct: 1158 GPNG 1161 Score = 436 bits (1120), Expect = e-122 Identities = 275/663 (41%), Positives = 314/663 (47%), Gaps = 137/663 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGECG 301 G G PG PG G G G +GP G+PG + G G GP G PG +G G RG+ G Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTS--GPPGSAGPPGSPGPQGSTGPQGIRGQPG 468 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG--- 358 PG+ G KG GP G GP GIQG GPPG+ G +G +G+ G GPPGP G GAPG Sbjct: 469 DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528 Query: 359 -------------------IGQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPR---G 392 +G G KG +G GRPG PG G G PG GP G Sbjct: 529 FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLG 588 Query: 393 PEGVPGERGLPGE-------------GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIG 438 P G PGE G PG G PGPKG G G G G G+ +G G G Sbjct: 589 PLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648 Query: 439 PVGPQGPMGIPGI-GSQGEQGIQGPI------GPPGPQG----PAGQGLPGSKGEVGQMG 487 VGP GP+G PG+ G +GEQG GP GPPGP G P QG+PG G VG +G Sbjct: 649 EVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLG 708 Query: 488 PTGPRG-------------------PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 P G RG G G GPKG PG G PG G PG G G++G Sbjct: 709 PRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERG 768 Query: 529 EAGLPGAR------------------------GPEGPPG-------KGQPGPKGDEGKKG 557 AG PG + GP GPPG KG+PGP+G G G Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPG 828 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG--- 613 S+GN G RG GP G G G GP G PG PG PG KGD G PG G G PG Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG 888 Query: 614 -LSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPG 670 + G KG +G +GP GA G G G G PGP G PGP GP+G G G G +G+PG Sbjct: 889 PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPG 948 Query: 671 VRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG----------YGSQGIKGEQGPQG 719 G G GP G G G KGD G+ G PGP GPPG G G +GE+G G Sbjct: 949 SHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPG 1008 Query: 720 FPGPKGTMG----------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769 PGP GT G G PG G G G VG+ G +G G G+PG+ G G +G Sbjct: 1009 LPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG 1068 Query: 770 DLG 772 D G Sbjct: 1069 DRG 1071 Score = 431 bits (1108), Expect = e-120 Identities = 272/596 (45%), Positives = 312/596 (52%), Gaps = 77/596 (12%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG PGP G+ G GI+G+ G G PG KGEAG +G G G +G G GE GK G Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGDPGVPGF--KGEAGPKGEPGPHGIQGPIGPPGEEGKRG 504 Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGD---PGPKGFQGNKGEPGPPGPYGSPGAPGI-G 360 +GD G+ GP GP G RG G G PG PGPKG QG +G G GP GS G PG G Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564 Query: 361 QQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEKG 415 + G+ G RG G PG GP G +G PG+ G GP G G RG PG G PGPKG G Sbjct: 565 EPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSG 624 Query: 416 SEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIG------PPG 467 G G G G+ +G G G VGP GP+G PG+ G +GEQG GP G PPG Sbjct: 625 DPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684 Query: 468 PQG----PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523 P G P QG+PG G VG +GP G RG G +GEPG GLPG+ G+ G G Sbjct: 685 PPGEGGKPGDQGVPGDPGAVGPLGPRGERGN-----PGERGEPGITGLPGEKGMAGGHGP 739 Query: 524 AGKKGEAGLPGARGPEGPPG----------KGQPGPKGD------EGKKGSKGNQGQRGL 567 G KG G G G GPPG G PGPKGD +G +G+ GN G RGL Sbjct: 740 DGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGL 799 Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRG 627 PGP GP PG GP G G PGP G G G G PG +GE G + G G GP+G Sbjct: 800 PGPLGP---PGPAGPTGEKGE--PGPRGLVGPPGSRGNPGSRGENGPT--GAVGFAGPQG 852 Query: 628 PVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPG 670 P G PG+KG+ G G PGP+GL G PGP G GV G GA G PG Sbjct: 853 PDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPG 912 Query: 671 VRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG 728 G GP GP G G GP G+ G++G PG G PG +G G +G GP G PG KG G Sbjct: 913 SAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG 972 Query: 729 H-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 G PG G G+RG VG G +GE G PG PG G G G G T ++ Sbjct: 973 EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028 Score = 424 bits (1090), Expect = e-118 Identities = 266/609 (43%), Positives = 309/609 (50%), Gaps = 87/609 (14%) Query: 245 GDPGDPGPPGTHGNPGIKG-------------ERGPKGNPGNAQKGEAGERGPGGIPGYK 291 G PG PGPPG +PG G E+ G+ G G GP G G + Sbjct: 168 GQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQ 227 Query: 292 GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G +G G G PG GD G GP G +GP G G G G+PG G G G G PG Sbjct: 228 GQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGAR 287 Query: 352 GSPGAPGI-------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLP 403 G PGAPG+ G +G++G +G+ G PG+ G G G G GP GP G+PGERG Sbjct: 288 GFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRL 347 Query: 404 G-EGFPGPKGE---KGSEGPTGPQGLQGLS-------IKGEKGDIGPVGPQGPMGIPGIG 452 G +G PG +G G GP GP G+ G S +KGE G G GP+GP G Sbjct: 348 GPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQ-----G 402 Query: 453 SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPG 507 +GE G GP+G PG G G G PG+KG G G +GP G G G QG G G Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQG 462 Query: 508 SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRG 566 G PG PGVPG G AG KGE G G +GP GPPG +G+ GP+GD G G G G+RG Sbjct: 463 IRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERG 522 Query: 567 LPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQG 624 PG G G G+ GP G G P G GPKG +G PG PG G PG + G GVQG Sbjct: 523 APGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582 Query: 625 PR---GPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG----------VGDTGAKGEPGV 671 P GP+GAPG DG PG PG G+ G PG MGL G G+ G G PG Sbjct: 583 PEGKLGPLGAPG--EDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640 Query: 672 RGPP------GPSGPRGV-------GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGE 714 RG P GPSGP G G QGP G TG +GLPGPPGPPG G QG+ G+ Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGD 700 Query: 715 QGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGL 764 G G GP+G G+ GLPG+KG G G G KG G G PG G GL Sbjct: 701 PGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGL 760 Query: 765 QGPKGDLGL 773 QG G+ G+ Sbjct: 761 QGMPGERGI 769 Score = 240 bits (613), Expect = 5e-63 Identities = 144/304 (47%), Positives = 165/304 (54%), Gaps = 28/304 (9%) Query: 245 GDPGDPGPPGTHGNPGIKG---ERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGER 297 G+PG GPPG G+PG G +RGP G PG GE G+ GP G PG G G+R Sbjct: 933 GEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992 Query: 298 GECGKPGIKGDKGSPGPYGPKG------PRGIQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G PG +G++G PG GP G P G G GPPG GP G G GEPGP GP Sbjct: 993 GIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA 1052 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----G 406 G+ G PG + G GERG G PG G P G PG PGP G G G+RG PG G Sbjct: 1053 GNDGTPG--RDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIG 1110 Query: 407 FPGPKGEKGSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQG 461 PG G++G GP GP+G +G +G+KG G G QG G PG G QG GI G Sbjct: 1111 PPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPG 1170 Query: 462 PIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGE 520 P GP GP GP G G G+ G +G +GP G RG VG GP+G PG G PG PG PG Sbjct: 1171 PFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEA--GPEGPPGEPGPPGPPGPPGH 1228 Query: 521 DGAA 524 AA Sbjct: 1229 LTAA 1232 Score = 232 bits (591), Expect = 2e-60 Identities = 163/389 (41%), Positives = 195/389 (50%), Gaps = 45/389 (11%) Query: 416 SEGPTGPQGLQGLSIKGEKGDIGPV-------GPQGPMGIPGIGSQGEQGIQGPIGPPGP 468 S+ P G G KG+KG+ G V G GP G PG SQG +G +GP G PGP Sbjct: 97 SQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPG--SQGPRGERGPKGRPGP 154 Query: 469 QGPAG-QGLPGSKGEVGQMGPTG-PRGPVGIGVQGP-----KGEPGSIGLPGQPGV-PGE 520 +GP G G PG G+ G GP G P P G+ P G GL Q G+ PG Sbjct: 155 RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGS 214 Query: 521 DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580 G G +G GL G +G GP G PG GD G G G++G G PG G GEPG Sbjct: 215 VGPVGPRGPQGLQGQQGGAGPTGP--PGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRN 272 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP 640 G G G + G PG +G G PG+PG KG RG KG++GP+G VGAPG KG+ P Sbjct: 273 GNPGEVGFA--GSPGARGFPGAPGLPGLKGH-----RGHKGLEGPKGEVGAPGSKGEAGP 325 Query: 641 GVP-------GPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDT 692 P GPRG+PG G +G +G G +G G+ G PGP GP G+ G+ G G+ Sbjct: 326 TGPMGAMGPLGPRGMPGERGRLGPQGA--PGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP 383 Query: 693 GQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKG 751 G KG GP G G G QG +GE GP PGP G+ PG G G G G KG G Sbjct: 384 GMKGEAGPTGARGPEGPQGQRGETGP---PGPVGS-----PGLPGAIGTDGTPGAKGPTG 435 Query: 752 EIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 G G PG G G G G T + I+ Sbjct: 436 SPGTSGPPGSAGPPGSPGPQGSTGPQGIR 464 Score = 36.6 bits (83), Expect = 0.14 Identities = 22/50 (44%), Positives = 25/50 (50%), Gaps = 8/50 (16%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGY 290 E G G GPPG G+ GE GP+G P GE G GP G PG+ Sbjct: 1187 EGNPGPLGPIGPPGVRGS---VGEAGPEGPP-----GEPGPPGPPGPPGH 1228 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 442 bits (1138), Expect = e-124 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG G G G G +G RGP G PG KG +G GP G PG +G +G +G G PG Sbjct: 886 GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 943 Query: 305 IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 KG G PG G +G G QG TGPPG G G QG GE GP G G PG PG Sbjct: 944 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 1003 Query: 359 I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416 G+QG+ G G+EG G PGP G+ G+ GP G G PGERGLPG +G PG KG +G Sbjct: 1004 PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 417 EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462 +GP GP G G + + G G GP GP G G PG G G G+QGP Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 463 IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512 +G PGP GPAG G PG KG G G GP GP G+ QGP G PG G Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1179 Query: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571 G+PG G+ G G+KG+ G G GP GP G +G PGP G++G+ G G G G PGP Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239 Query: 572 GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603 GP+G G GP G PG+ PGPPG PKG+RG GP Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299 Query: 604 ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641 G PG KG PG GPKG GP GP G G+ GD G PG Sbjct: 1300 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1357 Query: 642 VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682 PGP G GPPGP G RG G+ GAKGE G GPPG +GP G Sbjct: 1358 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1417 Query: 683 ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725 VG QG G GQ G PGP GPPG GS+G KG G G GP G Sbjct: 1418 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1477 Query: 726 TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G GLPG +G G +GD G G G +G PG PG G QGPKG+ G T Sbjct: 1478 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1530 Score = 440 bits (1132), Expect = e-123 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E GDPG GP G G PG G+ G +G P G G RG G PG KGD+G G G Sbjct: 566 ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 620 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358 PG KG +G GP GP GP G G+ G G+ GP+G G G G GP G+PGAPG Sbjct: 621 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 680 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414 G G KG G +G PG PG G G G PGP+GP G PGE+G +G PG G Sbjct: 681 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 738 Query: 415 GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473 G++GP G G +G S GEKG +GP GPQGP+G PG G +G G++G G G +G G Sbjct: 739 GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 796 Query: 474 -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516 GL G +GEVGQ+GP G GP G G G GE G +G+PG PG Sbjct: 797 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 856 Query: 517 VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 PG G G G G PGA G +G G G+PGP+G G G +G++G RG G GPKG Sbjct: 857 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 576 EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618 G GP G PG P GPPGP G G PG PG +GE G + G Sbjct: 917 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976 Query: 619 PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656 P GV GP+GP G G G+ G+PG PGP+G+ G GP G Sbjct: 977 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1036 Query: 657 LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705 LRG G GA+G PG++G GP GP G VG+ G +G G G PGP GPPG Sbjct: 1037 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1096 Query: 706 -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752 G +G GE+GPQ G PGP G G PG+ G+ GE G+ G+KG KG+ Sbjct: 1097 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1154 Query: 753 IGEPGSPGKQGLQGPKGDLGL 773 GE G PG GLQGP G G+ Sbjct: 1155 KGENGPPGPPGLQGPVGAPGI 1175 Score = 437 bits (1125), Expect = e-122 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299 E KG G G PG G G KG+ G G PG ++G G G G PG G+KG RG Sbjct: 825 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 884 Query: 300 CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347 GKPG +G +G GP GPKG G G GPPG+ GP+G QG G PGP Sbjct: 885 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944 Query: 348 PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393 GP G PG G+ G G +GE G +G+ G PGP GV GE G PGP GP Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 1004 Query: 394 EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439 PGE+GLPG +G PGP+G G +GP G +G G G KG GP Sbjct: 1005 ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 440 VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494 GP GP+G PG G+ G G+ G GP GP GPAG+ G PG KG G G G +GP Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 495 VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553 VG+ G GP G PG G G+ G PG+ G+ G KGE G PG G +GP G PG G + Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1179 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G+ G +G QG G G EG +G PG GP G+ G +PGPPG KG+ G G G G PG Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1237 Query: 614 -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668 +GP G GP+GP G+ G + G G G PG G PGPPG G+ G G+ G KGE Sbjct: 1238 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1297 Query: 669 -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720 PG GPPG GP G GPKG+ G G PG PGPPG G G KGE G G Sbjct: 1298 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1355 Query: 721 PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PGP G G G PG++ G G G G+KG KGE G G PGK G GP+G G Sbjct: 1356 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1414 Score = 436 bits (1121), Expect = e-122 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG +G +G+ GP G+ G+ G++G G G Sbjct: 995 ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1052 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362 PG+KG +G P GP GP G G G G GP G G G GPPGP G GAPG Sbjct: 1053 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1106 Query: 363 GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418 KG +G GR G GP+G+ PGP GP G PGE G GE G G KG+KG G Sbjct: 1107 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159 Query: 419 PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476 P GP GLQG + G G G GP+G G+ G +G++G +G GPPGP G G G Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1217 Query: 477 PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 PG KGE G +GP GP GP G G QGP G GS+G G+ G PGE G G Sbjct: 1218 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1277 Query: 527 KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 GEAG+ G +G G PPG G PG KG G G KGN G G PG GP GEPG Sbjct: 1278 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1337 Query: 580 MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632 G G+ G PGPPGP G+ G PG PG +G PG + G +G QG +G G Sbjct: 1338 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1395 Query: 633 GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683 G +G G G GP+G G PGP GLRG VG+ G G G GPPGP GP G+ Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455 Query: 684 ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729 G++G KG G GL GPPG G G+QG G +G G PGP G +G Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1515 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766 GLPG +G G +G G G KG+ G PG PG G G Sbjct: 1516 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 435 bits (1118), Expect = e-121 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300 G PG GPPG G G GE+G G PG G G +G G+ G KG KGE+GE Sbjct: 736 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 795 Query: 301 GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344 G PG KGD G G P G GP G +G GP GDPGP G G KG+ Sbjct: 796 GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 855 Query: 345 --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400 PG GP GS G PG G G KG RG G+PG G G G G G RGP G PG + Sbjct: 856 GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 915 Query: 401 GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443 G G +G PGP GE+G +GP GP G G +GE G G GP Sbjct: 916 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 975 Query: 444 GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493 GP G+ +G QG G GPIG PGP GP G QGLPG+ G+ G G GP+G Sbjct: 976 GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1033 Query: 494 PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 P G+ G G KG G G PG G PGE G+AG G GLPG GP+G Sbjct: 1034 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093 Query: 541 PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587 PPG KG PG KG +G G G QG GLPGP GP G PG G G PG Sbjct: 1094 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1153 Query: 588 ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633 PGPPG +G G PGI G GEPG G +G GP GP+G G Sbjct: 1154 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1213 Query: 634 LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673 L G G G GP G PGPPGP G +G VG G KGEPG G Sbjct: 1214 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1273 Query: 674 PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726 PGP G GVG GPKG+ G+KG GPPG PPG G G KG GP GFPG G Sbjct: 1274 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331 Query: 727 MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779 G G+ G KGE G+ G G G GE G PG PGK+G G G G E+ Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391 Query: 780 KLITEICGCGPKCKETPL 797 K E GP K P+ Sbjct: 1392 K--GEAGAEGPPGKTGPV 1407 Score = 433 bits (1113), Expect = e-121 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289 E+G G PGPPG G G GE GP+G PG A G+ G G G PG Sbjct: 629 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 688 Query: 290 YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334 KG+ G +GE G PG +G+ +G PGP GP GP G+ G GPPG PG Sbjct: 689 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 748 Query: 335 PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382 +G G KG GPPGP G G PG G +G KGE+G++G PG G +G+ Sbjct: 749 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 808 Query: 383 --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405 GE GQ GPRG + GVPG G PG Sbjct: 809 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 868 Query: 406 --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450 GFPG GEKG+ GPTGP+G +G +G G GP G G G PG Sbjct: 869 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 926 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502 G +G QG QGP+G PGP+GP G G PG +GE G G TGP GP G +G QGP Sbjct: 927 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 986 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558 GE G IG G PG PG G G G AG GA+G GP G G+ GP +G G++G Sbjct: 987 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1046 Query: 559 KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605 G QG GL G EGP+G P G GP G+PG P GPPGP G++G PG Sbjct: 1047 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1106 Query: 606 PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657 G +G G ++GP G+ GP GP G+PG GD G G G +G GPPGP GL Sbjct: 1107 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1166 Query: 658 RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709 + G G PG+ G G GPRG G G KGD G +G PGPPGP G G + Sbjct: 1167 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221 Query: 710 GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 G G+ GP G PGP G G G G G G G VG+KG+ GE G PG PG+ Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1281 Query: 763 GLQGPKGDLG 772 G+ GPKG+ G Sbjct: 1282 GVGGPKGERG 1291 Score = 421 bits (1083), Expect = e-117 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291 +G PG GP G G PG++G GP G+PG+ G G G G+PG Y Sbjct: 453 EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 512 Query: 292 GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317 GD G G G PG G KG G GP Sbjct: 513 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 572 Query: 318 KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370 +GPRG+QG GP G PG + G +G GEPG G G G PG+ G +G +GERG Sbjct: 573 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 632 Query: 371 EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413 +G PG PG G+ G PG+ GPR GP G PG G PG +G PGPKG Sbjct: 633 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692 Query: 414 KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473 G +G GP G Q G G G GPQGP+G P G +G QG G G PG GP G Sbjct: 693 MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 745 Query: 474 Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531 G G GE G +GP GP+GP+G G +G KG G GL G G GEDG G KG+ G Sbjct: 746 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 805 Query: 532 LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591 L G RG GQ GP+G++G +G KG G G PGP G GE G +G G+PG P Sbjct: 806 LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 858 Query: 592 GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635 G GPKG G PG PG GE G GP+G +G RGP G PG K Sbjct: 859 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 918 Query: 636 -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681 GDG PG PG RG GP GP+G G G G +GE G +G GP GP Sbjct: 919 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 978 Query: 682 G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729 G VG QGP G+T G++G PGPPGPPG G +G KG+ GPQG G G G Sbjct: 979 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1038 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773 G PG++G G +G G KG +G G P GSPG++G G G +GL Sbjct: 1039 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1085 Score = 308 bits (788), Expect = 2e-83 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%) Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384 PP PG P I G GE+GQ+G P G PGP G +G Sbjct: 408 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 467 Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444 PG GP GP G PG+RG PG PG G G GP G + G+ G GP Sbjct: 468 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 524 Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503 I Q ++GP GP G G P G PGS G G+ G GP+GP G VQGP Sbjct: 525 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 581 Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563 PG G PG+ G PG DG G GE G G RG +G PG GD+G +G +G QG Sbjct: 582 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 634 Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622 G PG +G +GE G +GP G+PG + P G GP+G G PG PG G G GPKG Sbjct: 635 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 692 Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682 GP+G G PG +G+ PGP+GLPGP GP+G G+ G +G+PG+ G PG GP G Sbjct: 693 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 745 Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738 G +G +G+KG GPPGP QGP G+PGP+G G GL G KGE Sbjct: 746 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 792 Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GE +GD+G KGD+GE+G+ G G+ G +GPKG G T Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 834 Score = 260 bits (664), Expect = 6e-69 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296 EKG+ GD PGPPG G G G GP+G PG+ G G G G PG G+ G Sbjct: 1220 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1277 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 GE G G KG++G G GP G G G GPPGD GPKG G G PG PGP G PG Sbjct: 1278 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1337 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414 G Q G+ G++G++G PG PGP G GE G PGP G G PG G G +G G KGE Sbjct: 1338 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1395 Query: 415 GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451 G+EGP G P+GL+G+ + G G GP GP GP G+PG+ Sbjct: 1396 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1455 Query: 452 ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504 G +G G+ G IGPPG QG G +GLPG++G G G G GP G GP G Sbjct: 1456 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1513 Query: 505 EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544 PG G G G G G AG+KG++GLPG G GPPG+ Sbjct: 1514 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553 Score = 204 bits (520), Expect = 3e-52 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%) Query: 243 EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 EKG+PG+ PGPPG G G KGERG KG G G AG G G PG G KG G Sbjct: 1265 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1322 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 G PG G G PGP G G G +G G PG PGP G G G PGPPG G PGA G Sbjct: 1323 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1382 Query: 360 ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405 G++G KGE G EG PG GP+G G G+PGP G G+PG E+GLPG Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1442 Query: 406 -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436 G PG KG+ GS+G G GL GL +GEKGD Sbjct: 1443 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1502 Query: 437 ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477 GP+GP GP G+PG G +G+ G+ GP G PGP G Q LP Sbjct: 1503 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559 Score = 149 bits (375), Expect = 2e-35 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%) Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597 P PP + + GP ++ + G G +G KGEP ++ P G + GPPGP Sbjct: 405 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 459 Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656 G G I GP G+QGP GP G PG +G G PG+PG GLPGPPG M Sbjct: 460 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 505 Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696 + G G+KG +RGPPGP G G G G G +G KG Sbjct: 506 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565 Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743 G PGP G +G++G GP G PG +G G G+PG+ G G+R GD Sbjct: 566 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G +G++G G PG PG G++G G++G Sbjct: 624 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 652 Score = 105 bits (263), Expect = 2e-22 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%) Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647 P P + GPG+P SI G G G +G G P G+ +G PG GP G Sbjct: 405 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 463 Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702 + GPPG G TG G+PG RGPPG G G GLPGPPG Sbjct: 464 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 507 Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741 P YG G KG +G PGP G G G PG G GE Sbjct: 508 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 567 Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776 GD G +G +G G PG PGK+G G G G+ E Sbjct: 568 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 605 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 442 bits (1138), Expect = e-124 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG G G G G +G RGP G PG KG +G GP G PG +G +G +G G PG Sbjct: 835 GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 892 Query: 305 IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 KG G PG G +G G QG TGPPG G G QG GE GP G G PG PG Sbjct: 893 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 952 Query: 359 I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416 G+QG+ G G+EG G PGP G+ G+ GP G G PGERGLPG +G PG KG +G Sbjct: 953 PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010 Query: 417 EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462 +GP GP G G + + G G GP GP G G PG G G G+QGP Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 463 IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512 +G PGP GPAG G PG KG G G GP GP G+ QGP G PG G Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1128 Query: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571 G+PG G+ G G+KG+ G G GP GP G +G PGP G++G+ G G G G PGP Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188 Query: 572 GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603 GP+G G GP G PG+ PGPPG PKG+RG GP Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248 Query: 604 ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641 G PG KG PG GPKG GP GP G G+ GD G PG Sbjct: 1249 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1306 Query: 642 VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682 PGP G GPPGP G RG G+ GAKGE G GPPG +GP G Sbjct: 1307 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1366 Query: 683 ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725 VG QG G GQ G PGP GPPG GS+G KG G G GP G Sbjct: 1367 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1426 Query: 726 TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G GLPG +G G +GD G G G +G PG PG G QGPKG+ G T Sbjct: 1427 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1479 Score = 440 bits (1132), Expect = e-123 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E GDPG GP G G PG G+ G +G P G G RG G PG KGD+G G G Sbjct: 515 ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 569 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358 PG KG +G GP GP GP G G+ G G+ GP+G G G G GP G+PGAPG Sbjct: 570 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 629 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414 G G KG G +G PG PG G G G PGP+GP G PGE+G +G PG G Sbjct: 630 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 687 Query: 415 GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473 G++GP G G +G S GEKG +GP GPQGP+G PG G +G G++G G G +G G Sbjct: 688 GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 745 Query: 474 -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516 GL G +GEVGQ+GP G GP G G G GE G +G+PG PG Sbjct: 746 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 805 Query: 517 VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 PG G G G G PGA G +G G G+PGP+G G G +G++G RG G GPKG Sbjct: 806 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865 Query: 576 EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618 G GP G PG P GPPGP G G PG PG +GE G + G Sbjct: 866 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925 Query: 619 PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656 P GV GP+GP G G G+ G+PG PGP+G+ G GP G Sbjct: 926 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 985 Query: 657 LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705 LRG G GA+G PG++G GP GP G VG+ G +G G G PGP GPPG Sbjct: 986 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1045 Query: 706 -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752 G +G GE+GPQ G PGP G G PG+ G+ GE G+ G+KG KG+ Sbjct: 1046 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1103 Query: 753 IGEPGSPGKQGLQGPKGDLGL 773 GE G PG GLQGP G G+ Sbjct: 1104 KGENGPPGPPGLQGPVGAPGI 1124 Score = 437 bits (1125), Expect = e-122 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299 E KG G G PG G G KG+ G G PG ++G G G G PG G+KG RG Sbjct: 774 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 833 Query: 300 CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347 GKPG +G +G GP GPKG G G GPPG+ GP+G QG G PGP Sbjct: 834 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893 Query: 348 PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393 GP G PG G+ G G +GE G +G+ G PGP GV GE G PGP GP Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 953 Query: 394 EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439 PGE+GLPG +G PGP+G G +GP G +G G G KG GP Sbjct: 954 ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1010 Query: 440 VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494 GP GP+G PG G+ G G+ G GP GP GPAG+ G PG KG G G G +GP Sbjct: 1011 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 495 VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553 VG+ G GP G PG G G+ G PG+ G+ G KGE G PG G +GP G PG G + Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1128 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G+ G +G QG G G EG +G PG GP G+ G +PGPPG KG+ G G G G PG Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1186 Query: 614 -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668 +GP G GP+GP G+ G + G G G PG G PGPPG G+ G G+ G KGE Sbjct: 1187 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1246 Query: 669 -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720 PG GPPG GP G GPKG+ G G PG PGPPG G G KGE G G Sbjct: 1247 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1304 Query: 721 PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PGP G G G PG++ G G G G+KG KGE G G PGK G GP+G G Sbjct: 1305 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1363 Score = 436 bits (1121), Expect = e-122 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG +G +G+ GP G+ G+ G++G G G Sbjct: 944 ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1001 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362 PG+KG +G P GP GP G G G G GP G G G GPPGP G GAPG Sbjct: 1002 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1055 Query: 363 GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418 KG +G GR G GP+G+ PGP GP G PGE G GE G G KG+KG G Sbjct: 1056 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108 Query: 419 PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476 P GP GLQG + G G G GP+G G+ G +G++G +G GPPGP G G G Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1166 Query: 477 PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 PG KGE G +GP GP GP G G QGP G GS+G G+ G PGE G G Sbjct: 1167 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1226 Query: 527 KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 GEAG+ G +G G PPG G PG KG G G KGN G G PG GP GEPG Sbjct: 1227 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1286 Query: 580 MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632 G G+ G PGPPGP G+ G PG PG +G PG + G +G QG +G G Sbjct: 1287 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1344 Query: 633 GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683 G +G G G GP+G G PGP GLRG VG+ G G G GPPGP GP G+ Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404 Query: 684 ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729 G++G KG G GL GPPG G G+QG G +G G PGP G +G Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1464 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766 GLPG +G G +G G G KG+ G PG PG G G Sbjct: 1465 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 435 bits (1118), Expect = e-121 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300 G PG GPPG G G GE+G G PG G G +G G+ G KG KGE+GE Sbjct: 685 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 744 Query: 301 GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344 G PG KGD G G P G GP G +G GP GDPGP G G KG+ Sbjct: 745 GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 804 Query: 345 --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400 PG GP GS G PG G G KG RG G+PG G G G G G RGP G PG + Sbjct: 805 GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 864 Query: 401 GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443 G G +G PGP GE+G +GP GP G G +GE G G GP Sbjct: 865 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 924 Query: 444 GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493 GP G+ +G QG G GPIG PGP GP G QGLPG+ G+ G G GP+G Sbjct: 925 GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 982 Query: 494 PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 P G+ G G KG G G PG G PGE G+AG G GLPG GP+G Sbjct: 983 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042 Query: 541 PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587 PPG KG PG KG +G G G QG GLPGP GP G PG G G PG Sbjct: 1043 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1102 Query: 588 ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633 PGPPG +G G PGI G GEPG G +G GP GP+G G Sbjct: 1103 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1162 Query: 634 LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673 L G G G GP G PGPPGP G +G VG G KGEPG G Sbjct: 1163 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1222 Query: 674 PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726 PGP G GVG GPKG+ G+KG GPPG PPG G G KG GP GFPG G Sbjct: 1223 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280 Query: 727 MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779 G G+ G KGE G+ G G G GE G PG PGK+G G G G E+ Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340 Query: 780 KLITEICGCGPKCKETPL 797 K E GP K P+ Sbjct: 1341 K--GEAGAEGPPGKTGPV 1356 Score = 433 bits (1113), Expect = e-121 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289 E+G G PGPPG G G GE GP+G PG A G+ G G G PG Sbjct: 578 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 637 Query: 290 YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334 KG+ G +GE G PG +G+ +G PGP GP GP G+ G GPPG PG Sbjct: 638 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 697 Query: 335 PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382 +G G KG GPPGP G G PG G +G KGE+G++G PG G +G+ Sbjct: 698 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 757 Query: 383 --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405 GE GQ GPRG + GVPG G PG Sbjct: 758 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 817 Query: 406 --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450 GFPG GEKG+ GPTGP+G +G +G G GP G G G PG Sbjct: 818 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 875 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502 G +G QG QGP+G PGP+GP G G PG +GE G G TGP GP G +G QGP Sbjct: 876 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 935 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558 GE G IG G PG PG G G G AG GA+G GP G G+ GP +G G++G Sbjct: 936 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 995 Query: 559 KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605 G QG GL G EGP+G P G GP G+PG P GPPGP G++G PG Sbjct: 996 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1055 Query: 606 PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657 G +G G ++GP G+ GP GP G+PG GD G G G +G GPPGP GL Sbjct: 1056 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1115 Query: 658 RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709 + G G PG+ G G GPRG G G KGD G +G PGPPGP G G + Sbjct: 1116 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170 Query: 710 GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 G G+ GP G PGP G G G G G G G VG+KG+ GE G PG PG+ Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1230 Query: 763 GLQGPKGDLG 772 G+ GPKG+ G Sbjct: 1231 GVGGPKGERG 1240 Score = 421 bits (1083), Expect = e-117 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291 +G PG GP G G PG++G GP G+PG+ G G G G+PG Y Sbjct: 402 EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 461 Query: 292 GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317 GD G G G PG G KG G GP Sbjct: 462 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 521 Query: 318 KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370 +GPRG+QG GP G PG + G +G GEPG G G G PG+ G +G +GERG Sbjct: 522 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581 Query: 371 EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413 +G PG PG G+ G PG+ GPR GP G PG G PG +G PGPKG Sbjct: 582 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641 Query: 414 KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473 G +G GP G Q G G G GPQGP+G P G +G QG G G PG GP G Sbjct: 642 MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 694 Query: 474 Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531 G G GE G +GP GP+GP+G G +G KG G GL G G GEDG G KG+ G Sbjct: 695 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 754 Query: 532 LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591 L G RG GQ GP+G++G +G KG G G PGP G GE G +G G+PG P Sbjct: 755 LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 807 Query: 592 GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635 G GPKG G PG PG GE G GP+G +G RGP G PG K Sbjct: 808 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 867 Query: 636 -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681 GDG PG PG RG GP GP+G G G G +GE G +G GP GP Sbjct: 868 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 927 Query: 682 G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729 G VG QGP G+T G++G PGPPGPPG G +G KG+ GPQG G G G Sbjct: 928 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 987 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773 G PG++G G +G G KG +G G P GSPG++G G G +GL Sbjct: 988 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1034 Score = 308 bits (788), Expect = 2e-83 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%) Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384 PP PG P I G GE+GQ+G P G PGP G +G Sbjct: 357 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 416 Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444 PG GP GP G PG+RG PG PG G G GP G + G+ G GP Sbjct: 417 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 473 Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503 I Q ++GP GP G G P G PGS G G+ G GP+GP G VQGP Sbjct: 474 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 530 Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563 PG G PG+ G PG DG G GE G G RG +G PG GD+G +G +G QG Sbjct: 531 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 583 Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622 G PG +G +GE G +GP G+PG + P G GP+G G PG PG G G GPKG Sbjct: 584 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 641 Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682 GP+G G PG +G+ PGP+GLPGP GP+G G+ G +G+PG+ G PG GP G Sbjct: 642 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 694 Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738 G +G +G+KG GPPGP QGP G+PGP+G G GL G KGE Sbjct: 695 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 741 Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GE +GD+G KGD+GE+G+ G G+ G +GPKG G T Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 783 Score = 260 bits (664), Expect = 6e-69 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296 EKG+ GD PGPPG G G G GP+G PG+ G G G G PG G+ G Sbjct: 1169 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1226 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 GE G G KG++G G GP G G G GPPGD GPKG G G PG PGP G PG Sbjct: 1227 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1286 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414 G Q G+ G++G++G PG PGP G GE G PGP G G PG G G +G G KGE Sbjct: 1287 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1344 Query: 415 GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451 G+EGP G P+GL+G+ + G G GP GP GP G+PG+ Sbjct: 1345 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1404 Query: 452 ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504 G +G G+ G IGPPG QG G +GLPG++G G G G GP G GP G Sbjct: 1405 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1462 Query: 505 EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544 PG G G G G G AG+KG++GLPG G GPPG+ Sbjct: 1463 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502 Score = 204 bits (520), Expect = 3e-52 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%) Query: 243 EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 EKG+PG+ PGPPG G G KGERG KG G G AG G G PG G KG G Sbjct: 1214 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1271 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 G PG G G PGP G G G +G G PG PGP G G G PGPPG G PGA G Sbjct: 1272 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1331 Query: 360 ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405 G++G KGE G EG PG GP+G G G+PGP G G+PG E+GLPG Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1391 Query: 406 -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436 G PG KG+ GS+G G GL GL +GEKGD Sbjct: 1392 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1451 Query: 437 ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477 GP+GP GP G+PG G +G+ G+ GP G PGP G Q LP Sbjct: 1452 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508 Score = 149 bits (375), Expect = 2e-35 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%) Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597 P PP + + GP ++ + G G +G KGEP ++ P G + GPPGP Sbjct: 354 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 408 Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656 G G I GP G+QGP GP G PG +G G PG+PG GLPGPPG M Sbjct: 409 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 454 Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696 + G G+KG +RGPPGP G G G G G +G KG Sbjct: 455 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514 Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743 G PGP G +G++G GP G PG +G G G+PG+ G G+R GD Sbjct: 515 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G +G++G G PG PG G++G G++G Sbjct: 573 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 601 Score = 105 bits (263), Expect = 2e-22 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%) Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647 P P + GPG+P SI G G G +G G P G+ +G PG GP G Sbjct: 354 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 412 Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702 + GPPG G TG G+PG RGPPG G G GLPGPPG Sbjct: 413 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 456 Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741 P YG G KG +G PGP G G G PG G GE Sbjct: 457 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 516 Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776 GD G +G +G G PG PGK+G G G G+ E Sbjct: 517 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 554 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 442 bits (1138), Expect = e-124 Identities = 284/653 (43%), Positives = 322/653 (49%), Gaps = 131/653 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG G G G G +G RGP G PG KG +G GP G PG +G +G +G G PG Sbjct: 874 GKPGPRGQRGPTGPRGSRGARGPTGKPG--PKGTSGGDGPPGPPGERGPQGPQGPVGFPG 931 Query: 305 IKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 KG G PG G +G G QG TGPPG G G QG GE GP G G PG PG Sbjct: 932 PKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG 991 Query: 359 I-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKGS 416 G+QG+ G G+EG G PGP G+ G+ GP G G PGERGLPG +G PG KG +G Sbjct: 992 PPGEQGLPGAAGKEGAKGDPGPQGIS--GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049 Query: 417 EGPTGPQGLQG----------LSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGP 462 +GP GP G G + + G G GP GP G G PG G G G+QGP Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 463 IGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLP 512 +G PGP GPAG G PG KG G G GP GP G+ QGP G PG G Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL--QGPVGAPGIAGGD 1167 Query: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPE 571 G+PG G+ G G+KG+ G G GP GP G +G PGP G++G+ G G G G PGP Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227 Query: 572 GPKGEPGIMGPFGMPGT----------------SIPGPPG------PKGDRG-----GP- 603 GP+G G GP G PG+ PGPPG PKG+RG GP Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287 Query: 604 ---GIPGFKGEPGLSIRGPKGVQGP------------RGPVGAPGLKGD-------GYPG 641 G PG KG PG GPKG GP GP G G+ GD G PG Sbjct: 1288 GAAGPPGAKGPPGDD--GPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPG 1345 Query: 642 VPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRG--------- 682 PGP G GPPGP G RG G+ GAKGE G GPPG +GP G Sbjct: 1346 PPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPG 1405 Query: 683 ----------VGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKG 725 VG QG G GQ G PGP GPPG GS+G KG G G GP G Sbjct: 1406 PEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPG 1465 Query: 726 TMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 G GLPG +G G +GD G G G +G PG PG G QGPKG+ G T Sbjct: 1466 EQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST 1518 Score = 440 bits (1132), Expect = e-123 Identities = 272/621 (43%), Positives = 323/621 (52%), Gaps = 101/621 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E GDPG GP G G PG G+ G +G P G G RG G PG KGD+G G G Sbjct: 554 ESGDPGPQGPRGVQGPPGPTGKPGKRGRP-----GADGGRGMPGEPGAKGDRGFDGLPGL 608 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG---- 358 PG KG +G GP GP GP G G+ G G+ GP+G G G G GP G+PGAPG Sbjct: 609 PGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGM 668 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEK 414 G G KG G +G PG PG G G G PGP+GP G PGE+G +G PG G Sbjct: 669 AGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKG--PQGKPGLAGLP 726 Query: 415 GSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG 473 G++GP G G +G S GEKG +GP GPQGP+G PG G +G G++G G G +G G Sbjct: 727 GADGPPGHPGKEGQS--GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDG 784 Query: 474 -------QGLPGSKGEVGQMGPTGPRGPVG----------IGVQGPKGEPGSIGLPGQPG 516 GL G +GEVGQ+GP G GP G G G GE G +G+PG PG Sbjct: 785 FPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844 Query: 517 VPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 PG G G G G PGA G +G G G+PGP+G G G +G++G RG G GPKG Sbjct: 845 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 576 EPGIMGPFGMPGTSIP-------------GPPGPKGDRGGPGIPGFKGEPGLSIR----G 618 G GP G PG P GPPGP G G PG PG +GE G + G Sbjct: 905 TSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964 Query: 619 PKGVQGPRGPVGAPGLKGD-GYPGV---------------------PGPRGLPGPPGPMG 656 P GV GP+GP G G G+ G+PG PGP+G+ G GP G Sbjct: 965 PGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG 1024 Query: 657 LRGV----GDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQ------KGLPGPPGPPG 705 LRG G GA+G PG++G GP GP G VG+ G +G G G PGP GPPG Sbjct: 1025 LRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPG 1084 Query: 706 -YGSQGIKGEQGPQ------------GFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGE 752 G +G GE+GPQ G PGP G G PG+ G+ GE G+ G+KG KG+ Sbjct: 1085 PAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS--PGEDGDKGEIGEPGQKGSKGD 1142 Query: 753 IGEPGSPGKQGLQGPKGDLGL 773 GE G PG GLQGP G G+ Sbjct: 1143 KGENGPPGPPGLQGPVGAPGI 1163 Score = 437 bits (1125), Expect = e-122 Identities = 271/599 (45%), Positives = 316/599 (52%), Gaps = 76/599 (12%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGE 299 E KG G G PG G G KG+ G G PG ++G G G G PG G+KG RG Sbjct: 813 EGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGV 872 Query: 300 CGKPGIKGDKGSPGPY------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGP 347 GKPG +G +G GP GPKG G G GPPG+ GP+G QG G PGP Sbjct: 873 AGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932 Query: 348 PGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-------------GEPGQPGPRGP 393 GP G PG G+ G G +GE G +G+ G PGP GV GE G PGP GP Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGP 992 Query: 394 EGVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG-------LSIKGEKGDIGP 439 PGE+GLPG +G PGP+G G +GP G +G G G KG GP Sbjct: 993 ---PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1049 Query: 440 VGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGP 494 GP GP+G PG G+ G G+ G GP GP GPAG+ G PG KG G G G +GP Sbjct: 1050 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 495 VGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553 VG+ G GP G PG G G+ G PG+ G+ G KGE G PG G +GP G PG G + Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGGD 1167 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G+ G +G QG G G EG +G PG GP G+ G +PGPPG KG+ G G G G PG Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG--LPGPPGEKGENGDVGPMGPPGPPG 1225 Query: 614 -LSIRGPKGVQGPRGPVGAPG-LKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGE-- 668 +GP G GP+GP G+ G + G G G PG G PGPPG G+ G G+ G KGE Sbjct: 1226 PRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG 1285 Query: 669 -PGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGF 720 PG GPPG GP G GPKG+ G G PG PGPPG G G KGE G G Sbjct: 1286 PPGAAGPPGAKGP--PGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQ 1343 Query: 721 PGPKGTMGH----GLPGQK---GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PGP G G G PG++ G G G G+KG KGE G G PGK G GP+G G Sbjct: 1344 PGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAG 1402 Score = 436 bits (1121), Expect = e-122 Identities = 262/577 (45%), Positives = 308/577 (53%), Gaps = 72/577 (12%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG +G +G+ GP G+ G+ G++G G G Sbjct: 983 ERGHPGPPGPPGEQGLPGAAGKEGAKGDPG--PQGISGKDGPAGLRGFPGERGLPGAQGA 1040 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362 PG+KG +G P GP GP G G G G GP G G G GPPGP G GAPG Sbjct: 1041 PGLKGGEG---PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE--- 1094 Query: 363 GIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEG 418 KG +G GR G GP+G+ PGP GP G PGE G GE G G KG+KG G Sbjct: 1095 --KGPQGPAGRDGVQGPVGL-----PGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147 Query: 419 PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGL 476 P GP GLQG + G G G GP+G G+ G +G++G +G GPPGP G G G Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM--FGQKGDEGARGFPGPPGPIGLQGLPGP 1205 Query: 477 PGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGK 526 PG KGE G +GP GP GP G G QGP G GS+G G+ G PGE G G Sbjct: 1206 PGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGP 1265 Query: 527 KGEAGLPGARGPEG------PPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 GEAG+ G +G G PPG G PG KG G G KGN G G PG GP GEPG Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325 Query: 580 MGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632 G G+ G PGPPGP G+ G PG PG +G PG + G +G QG +G G Sbjct: 1326 AGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEA 1383 Query: 633 GLKGD-GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV---- 683 G +G G G GP+G G PGP GLRG VG+ G G G GPPGP GP G+ Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1443 Query: 684 ---GTQGPKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMGH---- 729 G++G KG G GL GPPG G G+QG G +G G PGP G +G Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPP 1503 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQG 766 GLPG +G G +G G G KG+ G PG PG G G Sbjct: 1504 GLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 435 bits (1118), Expect = e-121 Identities = 291/678 (42%), Positives = 323/678 (47%), Gaps = 131/678 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300 G PG GPPG G G GE+G G PG G G +G G+ G KG KGE+GE Sbjct: 724 GLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGED 783 Query: 301 GKPGIKGDKGSPG---------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGE------- 344 G PG KGD G G P G GP G +G GP GDPGP G G KG+ Sbjct: 784 GFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLP 843 Query: 345 --PGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGER 400 PG GP GS G PG G G KG RG G+PG G G G G G RGP G PG + Sbjct: 844 GYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPK 903 Query: 401 GLPG-EGFPGPKGEKGSEGPTGPQGLQGLS----------------IKGEKGDIGPVGPQ 443 G G +G PGP GE+G +GP GP G G +GE G G GP Sbjct: 904 GTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPP 963 Query: 444 GPMGIPGIGSQGEQGIQGPIGP---PGPQGPAG-QGLPGSKGEVGQMGPTGPRG------ 493 GP G+ +G QG G GPIG PGP GP G QGLPG+ G+ G G GP+G Sbjct: 964 GPGGV--VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDG 1021 Query: 494 PVGI-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG 540 P G+ G G KG G G PG G PGE G+AG G GLPG GP+G Sbjct: 1022 PAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081 Query: 541 PPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI---MGPFGMPG------ 587 PPG KG PG KG +G G G QG GLPGP GP G PG G G PG Sbjct: 1082 PPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG 1141 Query: 588 ----TSIPGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPG 633 PGPPG +G G PGI G GEPG G +G GP GP+G G Sbjct: 1142 DKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQG 1201 Query: 634 LKGD----GYPGVPGPRGLPGPPGPMGLRG----------------VGDTGAKGEPGVRG 673 L G G G GP G PGPPGP G +G VG G KGEPG G Sbjct: 1202 LPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAG 1261 Query: 674 PPGPSGPRGVGTQGPKGDTGQKGLPGPPG---PPGY----GSQGIKGEQGPQGFPGPKGT 726 PGP G GVG GPKG+ G+KG GPPG PPG G G KG GP GFPG G Sbjct: 1262 NPGPPGEAGVG--GPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319 Query: 727 MGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEII 779 G G+ G KGE G+ G G G GE G PG PGK+G G G G E+ Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379 Query: 780 KLITEICGCGPKCKETPL 797 K E GP K P+ Sbjct: 1380 K--GEAGAEGPPGKTGPV 1395 Score = 433 bits (1113), Expect = e-121 Identities = 280/670 (41%), Positives = 331/670 (49%), Gaps = 147/670 (21%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------------QKGEAGERGPGGIPG 289 E+G G PGPPG G G GE GP+G PG A G+ G G G PG Sbjct: 617 ERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPG 676 Query: 290 YKGDKGERGECGKPGIKGD---KGSPGPYGPKGP------------RGIQGITGPPGDPG 334 KG+ G +GE G PG +G+ +G PGP GP GP G+ G GPPG PG Sbjct: 677 PKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPG 736 Query: 335 PKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV-- 382 +G G KG GPPGP G G PG G +G KGE+G++G PG G +G+ Sbjct: 737 KEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKG 796 Query: 383 --GEPGQPGPRGPE---------------------------GVPGERGLPGE-------- 405 GE GQ GPRG + GVPG G PG Sbjct: 797 DRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTG 856 Query: 406 --GFPGPKGEKGS------------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG- 450 GFPG GEKG+ GPTGP+G +G +G G GP G G G PG Sbjct: 857 FPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG--ARGPTGKPGPKGTSGGDGPPGP 914 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-------QGLPGSKGEVGQMGPTGPRGPVG-IGVQGP 502 G +G QG QGP+G PGP+GP G G PG +GE G G TGP GP G +G QGP Sbjct: 915 PGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGP 974 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP---KGDEGKKGS 558 GE G IG G PG PG G G G AG GA+G GP G G+ GP +G G++G Sbjct: 975 TGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGL 1034 Query: 559 KGNQGQRGLPGPEGPKGEP------------GIMGPFGMPGTSIP-GPPGPKGDRGGPGI 605 G QG GL G EGP+G P G GP G+PG P GPPGP G++G PG Sbjct: 1035 PGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGE 1094 Query: 606 PGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGL 657 G +G G ++GP G+ GP GP G+PG GD G G G +G GPPGP GL Sbjct: 1095 KGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGL 1154 Query: 658 RGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-------GSQ 709 + G G PG+ G G GPRG G G KGD G +G PGPPGP G G + Sbjct: 1155 Q-----GPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209 Query: 710 GIKGEQGPQGFPGPKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQ 762 G G+ GP G PGP G G G G G G G VG+KG+ GE G PG PG+ Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA 1269 Query: 763 GLQGPKGDLG 772 G+ GPKG+ G Sbjct: 1270 GVGGPKGERG 1279 Score = 421 bits (1083), Expect = e-117 Identities = 271/647 (41%), Positives = 319/647 (49%), Gaps = 131/647 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPG-----------YK 291 +G PG GP G G PG++G GP G+PG+ G G G G+PG Y Sbjct: 441 EGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYG 500 Query: 292 GD----------------------------------KGERGECGKPGIKGDKGSPGPYGP 317 GD G G G PG G KG G GP Sbjct: 501 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 560 Query: 318 KGPRGIQGITGPPGDPGPK------GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQ 370 +GPRG+QG GP G PG + G +G GEPG G G G PG+ G +G +GERG Sbjct: 561 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620 Query: 371 EGRPGAPGPIGV----------GEPGQPGPR---GPEGVPGERGLPG----EGFPGPKGE 413 +G PG PG G+ G PG+ GPR GP G PG G PG +G PGPKG Sbjct: 621 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680 Query: 414 KGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG 473 G +G GP G Q G G G GPQGP+G P G +G QG G G PG GP G Sbjct: 681 MGPQGEPGPPGQQ-----GNPGPQGLPGPQGPIGPP--GEKGPQGKPGLAGLPGADGPPG 733 Query: 474 Q-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531 G G GE G +GP GP+GP+G G +G KG G GL G G GEDG G KG+ G Sbjct: 734 HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMG 793 Query: 532 LPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP 591 L G RG GQ GP+G++G +G KG G G PGP G GE G +G G+PG P Sbjct: 794 LKGDRGE-----VGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG--YP 846 Query: 592 GPPGPKGDRGGPGIPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLK--- 635 G GPKG G PG PG GE G GP+G +G RGP G PG K Sbjct: 847 GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTS 906 Query: 636 -GDGYPGVPGPRGLPGPPGPMGLRG-------------VGDTGAKGEPGVRGPPGPSGPR 681 GDG PG PG RG GP GP+G G G G +GE G +G GP GP Sbjct: 907 GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG 966 Query: 682 G-VGTQGPKGDT---GQKGLPGPPGPPG-------YGSQGIKGEQGPQGFPGPKGTMG-H 729 G VG QGP G+T G++G PGPPGPPG G +G KG+ GPQG G G G Sbjct: 967 GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLR 1026 Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEP---GSPGKQGLQGPKGDLGL 773 G PG++G G +G G KG +G G P GSPG++G G G +GL Sbjct: 1027 GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGL 1073 Score = 308 bits (788), Expect = 2e-83 Identities = 197/462 (42%), Positives = 239/462 (51%), Gaps = 69/462 (14%) Query: 347 PPGPYGSPGAPG--------IGQQGIKGERGQEGRP----------GAPGPIG----VGE 384 PP PG P I G GE+GQ+G P G PGP G +G Sbjct: 396 PPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGP 455 Query: 385 PGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQG 444 PG GP GP G PG+RG PG PG G G GP G + G+ G GP Sbjct: 456 PGLQGPTGPPGDPGDRGPPGR--PGLPGADGLPGPPGTMLMLPFRYGGD-GSKGPTISAQ 512 Query: 445 PMGIPGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPK 503 I Q ++GP GP G G P G PGS G G+ G GP+GP G VQGP Sbjct: 513 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG--VQGP- 569 Query: 504 GEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQG 563 PG G PG+ G PG DG G GE G G RG +G PG GD+G +G +G QG Sbjct: 570 --PGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGL-----PGDKGHRGERGPQG 622 Query: 564 QRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGV 622 G PG +G +GE G +GP G+PG + P G GP+G G PG PG G G GPKG Sbjct: 623 PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPP--GPKGN 680 Query: 623 QGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG 682 GP+G G PG +G+ PGP+GLPGP GP+G G+ G +G+PG+ G PG GP G Sbjct: 681 MGPQGEPGPPGQQGN-----PGPQGLPGPQGPIG--PPGEKGPQGKPGLAGLPGADGPPG 733 Query: 683 VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEH 738 G +G +G+KG GPPGP QGP G+PGP+G G GL G KGE Sbjct: 734 --HPGKEGQSGEKGALGPPGP-----------QGPIGYPGPRGVKGADGVRGLKGSKGEK 780 Query: 739 GE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GE +GD+G KGD+GE+G+ G G+ G +GPKG G T Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPT 822 Score = 260 bits (664), Expect = 6e-69 Identities = 153/340 (45%), Positives = 181/340 (53%), Gaps = 44/340 (12%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296 EKG+ GD PGPPG G G G GP+G PG+ G G G G PG G+ G Sbjct: 1208 EKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--GSVGGVGEKGEPGEAGNPGP 1265 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 GE G G KG++G G GP G G G GPPGD GPKG G G PG PGP G PG Sbjct: 1266 PGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGP 1325 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414 G Q G+ G++G++G PG PGP G GE G PGP G G PG G G +G G KGE Sbjct: 1326 AG--QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEA 1383 Query: 415 GSEGPTG---------------PQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI- 451 G+EGP G P+GL+G+ + G G GP GP GP G+PG+ Sbjct: 1384 GAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLK 1443 Query: 452 ------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504 G +G G+ G IGPPG QG G +GLPG++G G G G GP G GP G Sbjct: 1444 GDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPG 1501 Query: 505 EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544 PG G G G G G AG+KG++GLPG G GPPG+ Sbjct: 1502 PPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541 Score = 204 bits (520), Expect = 3e-52 Identities = 129/297 (43%), Positives = 146/297 (49%), Gaps = 64/297 (21%) Query: 243 EKGDPGD---PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 EKG+PG+ PGPPG G G KGERG KG G G AG G G PG G KG G Sbjct: 1253 EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAG--PPGAAGPPGAKGPPGDDGPKGNPGP 1310 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 G PG G G PGP G G G +G G PG PGP G G G PGPPG G PGA G Sbjct: 1311 VGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGA 1370 Query: 360 ----GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG---ERGLPGE------ 405 G++G KGE G EG PG GP+G G G+PGP G G+PG E+GLPG Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGP 1430 Query: 406 -------GFPGPKGEKGSEGPTGPQGLQGL----SIKGEKGD------------------ 436 G PG KG+ GS+G G GL GL +GEKGD Sbjct: 1431 PGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGI 1490 Query: 437 ---IGPVGPQGPMGIPG-------------IGSQGEQGIQGPIGPPGPQGPAGQGLP 477 GP+GP GP G+PG G +G+ G+ GP G PGP G Q LP Sbjct: 1491 PGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547 Score = 149 bits (375), Expect = 2e-35 Identities = 99/269 (36%), Positives = 129/269 (47%), Gaps = 55/269 (20%) Query: 538 PEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPK 597 P PP + + GP ++ + G G +G KGEP ++ P G + GPPGP Sbjct: 393 PTSPPNE-EFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEP----GMLVEGPPGPA 447 Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG 656 G G I GP G+QGP GP G PG +G G PG+PG GLPGPPG M Sbjct: 448 GPAG--------------IMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTML 493 Query: 657 LRGV--GDTGAKGEP-----------------GVRGPPGPSGPRG-VGTQGPKGDTGQKG 696 + G G+KG +RGPPGP G G G G G +G KG Sbjct: 494 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553 Query: 697 LPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGER---------GD 743 G PGP G +G++G GP G PG +G G G+PG+ G G+R GD Sbjct: 554 ESGDPGPQG--PRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G +G++G G PG PG G++G G++G Sbjct: 612 KGHRGERGPQGPPGPPGDDGMRGEDGEIG 640 Score = 105 bits (263), Expect = 2e-22 Identities = 79/218 (36%), Positives = 91/218 (41%), Gaps = 51/218 (23%) Query: 593 PPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP-----GLKGDGYPGVPGPRG 647 P P + GPG+P SI G G G +G G P G+ +G PG GP G Sbjct: 393 PTSPPNEEFGPGVPAETDITETSING-HGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG 451 Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG----- 702 + GPPG G TG G+PG RGPPG G G GLPGPPG Sbjct: 452 IMGPPGLQG-----PTGPPGDPGDRGPPGRPGLPGAD-----------GLPGPPGTMLML 495 Query: 703 PPGYGSQGIKGEQ-----------------GPQGFPGPKGTMGH----GLPGQKGEHGER 741 P YG G KG +G PGP G G G PG G GE Sbjct: 496 PFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGES 555 Query: 742 GDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776 GD G +G +G G PG PGK+G G G G+ E Sbjct: 556 GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGE 593 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 441 bits (1135), Expect = e-123 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G GP G G G +G+RGP+G G + KG +G GP G PG +G G +G G Sbjct: 742 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 801 Query: 303 PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 PG KG G PG G +G G QG TGPPG PG G QG GE GP G G PG Sbjct: 802 PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 861 Query: 357 PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414 PG G+QG+ G G+EG G PGP G PG+ GP G G PGERGLPG G PG KG + Sbjct: 862 PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 919 Query: 415 GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460 G GP GP G G G G IGP G GP G PG IG G G+Q Sbjct: 920 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 979 Query: 461 GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497 GP+G PGP GP G +G G+KGE G GP GP GPVG Sbjct: 980 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1039 Query: 498 ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534 G +GP+G PG IGL G PG GE G G G G PG Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099 Query: 535 -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586 A GP+GPPG G GP G++G+ G G+ G +G PG +GP+GE G G G P Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159 Query: 587 GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637 G PGPPGPKG +G PG GF G+PG P G GPRG GA G +G+ Sbjct: 1160 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1212 Query: 638 -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680 G PG PGP G GPPGP+G RG GD GA G PG GP GP+GP Sbjct: 1213 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1272 Query: 681 RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720 G VG QG G TGQ G PGP GPPG G G KGE+G G Sbjct: 1273 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1332 Query: 721 ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 PG +G G GLPG +G G++G++G G G IG G PG G GPKG G T Sbjct: 1333 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1390 Score = 439 bits (1129), Expect = e-123 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294 G PG GPPGT GN G G +GP G PG KG GE+G G PG+KGD Sbjct: 605 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 664 Query: 295 GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345 G +G+ G+ G+ G +G GP GPKG TGP GDPGP G G KG+ P Sbjct: 665 GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 718 Query: 346 GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392 G GP GS G PG G G KG RG G+ G G G G GQ GPRG Sbjct: 719 GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 778 Query: 393 ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447 P G PGERGLPG GP G G +GP GP G GL G++G++G G GP G Sbjct: 779 GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 836 Query: 448 IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496 PG+ G+ GE G G G PGP GP G QGLPG+ G+ G G GP G P G Sbjct: 837 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 896 Query: 497 I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543 + G G KG G G PG G PGE GAAG G G PG GP+GPPG Sbjct: 897 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956 Query: 544 ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589 KG PG KG G G G QG GLPGP GP G E G G G PG Sbjct: 957 AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1016 Query: 590 ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634 PGPPGP G G PG G GEPG RGP +G GP GP+G GL Sbjct: 1017 EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1074 Query: 635 KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674 G G PG PGPRG GP G P G+ +G G KGEPG G Sbjct: 1075 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1134 Query: 675 PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733 PG G GV G +G +G+ G+ G PG PGPPG +G G+ GP+G PGP G G PG Sbjct: 1135 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1190 Query: 734 QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772 GE G RG G KGD+GE GE PGSPG G GP G LG Sbjct: 1191 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232 Score = 431 bits (1109), Expect = e-120 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G G G G+PG+KG+RG G PG +KG G+ G G+PG G+ GERG+ G+ Sbjct: 451 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356 G +G G GP G GP+G GI GPPG GPKG G +GEPGPPG G+PG Sbjct: 511 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 570 Query: 357 PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407 G+ G G GE+G +G+PG PG P G PG PG GP G G +G G G+ Sbjct: 571 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 630 Query: 408 PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463 PGP+G KG +G G +G +G G KGDIG G +G +G+P GS+GE G +GP Sbjct: 631 PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 688 Query: 464 GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522 G GP G G PG GE G++G G P P G QGPK GS+G PG PG GE G Sbjct: 689 GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 740 Query: 523 AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573 A G G++G G RGP GP +GQ GP+G GK G+KG G+RGLPGP+GP Sbjct: 741 ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798 Query: 574 KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602 G PG GP G PG T PGPP GP G+RG Sbjct: 799 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858 Query: 603 PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659 PG PG GE GL G +G +G GP GAPG G G G PG RGLPG G GL+G Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918 Query: 660 ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712 G G+ GE G G GP GP G G QGP G G+KG+PG GP G G Sbjct: 919 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 976 Query: 713 GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G QGP G PGP G G+ G+ G+ GE GD G+KG KG GE G PG G GP G G Sbjct: 977 GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1034 Score = 426 bits (1095), Expect = e-119 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG G G+ GP G+ G+ G++G G G Sbjct: 855 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 912 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347 PG+KG++G GP GP G G +G GPPG PGP KG G KG GP Sbjct: 913 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972 Query: 348 ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385 PGP G PG G GQ+G KG +G+ G PG PGPI G Sbjct: 973 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1030 Query: 386 GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443 GQPG G +G PG RG G G G +G +G GP GP GLQGL GEKG+ G VGP Sbjct: 1031 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090 Query: 444 GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501 GP G PG G G G GP GPPG G G PG KGE G+ G G +G G+ G +G Sbjct: 1091 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560 +GE G G PG+PG PG G G G G PG G G PG G+ GP+G +G KG +G Sbjct: 1149 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1208 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 G+ G PG GP GE G GP G G PG G +G +G G PG G PG + GP Sbjct: 1209 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1266 Query: 620 KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671 G GP G G GL+G G PG G G PGP GP GL G+ GD GAKGE G Sbjct: 1267 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1326 Query: 672 RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730 G G GP G QG KGD +GLPGP G PG G GI G GP G GP G G Sbjct: 1327 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1381 Query: 731 LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763 G KG G G G KG+KG G PG PG G Sbjct: 1382 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412 Score = 420 bits (1080), Expect = e-117 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279 GDPG+ GPPG G PG G GP G G KG Sbjct: 337 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 396 Query: 280 -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336 RGP G GY G G G+ G PG+KG+ G GP GP+GP QG+TGPPG G + Sbjct: 397 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 453 Query: 337 -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394 G G +G PG PG G G G+ G G KG RG G G PGP PG+ G RG + Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 508 Query: 395 GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450 G G RGLPGE P GPKG G GP G +G+ G +G KG +GP G GP G G Sbjct: 509 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 566 Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507 G+QG G QG IGP G +GP G+ GLPG G G G G GP G G QGP G G Sbjct: 567 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 626 Query: 508 SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 +G PG GV G DG G+KGE G PG +G G G G PG +G++G +G Sbjct: 627 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 686 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614 KG G G PGP G GE G +G G+PG PG GPKG G PG PG GE G Sbjct: 687 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 744 Query: 615 ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659 GP+G +GPRG G G K GDG G PG RGLPGP GP G G Sbjct: 745 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 804 Query: 660 ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703 G G +GE G +G GP GP G VG QG G+T G++G PGPPGP Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864 Query: 704 PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755 PG G +G KG+ GP G PG G G G PG++G G G G KG++G G Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924 Query: 756 P---GSPGKQGLQGPKGDLG 772 P GSPG++G G G +G Sbjct: 925 PGPAGSPGERGAAGSGGPIG 944 Score = 377 bits (967), Expect = e-104 Identities = 260/654 (39%), Positives = 308/654 (47%), Gaps = 132/654 (20%) Query: 233 KKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-----QKGEAGERGPG-- 285 + CE+K ECE G P H + +R P+ P Q+ ++ + PG Sbjct: 219 ESCEQKELECEGGQRERPQNQQPH-----RAQRSPQQQPSRLHRPQNQEPQSQDPTPGEE 273 Query: 286 --------------GIPGYKGDKGERGECG--KPG--IKGDKGSPGPYGPKGPRGIQGIT 327 G +G KGE+GE +PG ++G G GP G GP GIQG Sbjct: 274 EEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNP 333 Query: 328 GPPGDPGPKGFQGNKGEP------------------------------------------ 345 GP GDPG +G G G P Sbjct: 334 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 393 Query: 346 -------GPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGP 393 GPPGP G G PG G G+KGE G G G GP G+ G PG+ G RG Sbjct: 394 QARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGR 453 Query: 394 EGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQ 443 G G RG+PG +G PG GEKG G TG QGL G GE G+ G G Sbjct: 454 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEI 511 Query: 444 GPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502 GP G+P G G +G+ GP GPPG GP G +G+ G +G G +GP G GP G Sbjct: 512 GPRGLP--GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-----PGQ 564 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGN 561 +G PG+ GLPG G G G G +G+ GLPG G +GPPG G+ GP G +G +G G Sbjct: 565 QGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGP 624 Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGL 614 QG G PGP G KG GI G G G G G KGDRG G+PG +GE G Sbjct: 625 QGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG- 683 Query: 615 SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVR 672 GPKG GP G G PGL G+ G GVPG G PG GP G G G GA GE G R Sbjct: 684 -PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742 Query: 673 GPPGPSGPRGV-------GTQGPKGDTGQKGL------PGPPGPPGYGSQGIKGEQGPQG 719 G G SGPRG G +GP+G TG+ G GP GPP G +G+ G QGP G Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--GERGLPGPQGPNG 800 Query: 720 FPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 FPGPKG G G G G G+RG+VG +G G G PG G QG G G +G Sbjct: 801 FPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 854 Score = 306 bits (785), Expect = 5e-83 Identities = 202/469 (43%), Positives = 237/469 (50%), Gaps = 56/469 (11%) Query: 360 GQQGIKGERGQ----------EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP 408 G +G+KGE+G+ EG PG GP G +G PG G GP G PGERG PG Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 348 Query: 409 GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP--- 465 G G G+ GP G + GD GPV I Q ++GP GP Sbjct: 349 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 408 Query: 466 PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGE 520 G GP GQ G PG KGE G +GP GPRGP G+ G G +G G+ G G PG PG Sbjct: 409 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 468 Query: 521 DGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 G G G GLPG +G G G +G PGP G++G++G G G RGLPG GP+G G Sbjct: 469 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528 Query: 580 MGPFGMPGT----SIPGPPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGP 628 GP G+PG + GP GPKG +G PG PG +G PG + GP+G GP +GP Sbjct: 529 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588 Query: 629 VGAPGLKG----DGYPGVPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGP 677 G PGL G DG PG PG G PG P GP G G G G KG G+RG G Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648 Query: 678 SGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH--- 729 G +G G G KGD G KG G G PG G +G KG GP G PGP G MG Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708 Query: 730 ----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GLPG G G +G +G G G GE G+ G G GP+G+ G T Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 757 Score = 296 bits (757), Expect = 1e-79 Identities = 197/508 (38%), Positives = 254/508 (50%), Gaps = 85/508 (16%) Query: 338 FQGNKGE----PGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG------PIGVGEPGQ 387 F+G+ E PG Y S + +G + ER Q +P P + P Sbjct: 201 FEGDVQELAIVPGVQAAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQN 260 Query: 388 PGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI--GPVGPQGP 445 P+ + PGE E P E+ + GP G +G +G E G + GP GP+GP Sbjct: 261 QEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGP 320 Query: 446 MGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPT-----------GPRG 493 G+ IG G QG GP+G PG +GP G+ GLPGS G G G + G +G Sbjct: 321 AGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKG 378 Query: 494 PVGIGVQGP------------KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGP 541 PV + +G PG +G G+PG G+ G+ G KGE+G G +GP GP Sbjct: 379 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 438 Query: 542 PGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS----------IP 591 +G GP G G++G G G RG+PG G KG+ G G G+PG +P Sbjct: 439 --QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLP 496 Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGP 651 GPPG G+RG G G +G PG S GP+G+ GP+GP G PG PG RG+ GP Sbjct: 497 GPPGEDGERGDDGEIGPRGLPGES--GPRGLLGPKGP--------PGIPGPPGVRGMDGP 546 Query: 652 PGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY 706 GP G G G G +G PG +G PGP G G G +GP+G G G+PG GPPG+ Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606 Query: 707 ----------GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGE------RGDVGK 746 G+QG G QGP G+PGP+G G GL G KGE GE +GD+G Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666 Query: 747 KGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 KGD+GE+G PGS G+ G +GPKG G T Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPT 694 Score = 288 bits (737), Expect = 2e-77 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292 EKG+ GD PGPPG G G G GP+G PG GE GE G G PG +G Sbjct: 1080 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1139 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 + G +G G+ G KG+ G PG GP GP+G G GP G+PGP GF G+ G PG GP G Sbjct: 1140 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199 Query: 353 SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410 GA +G +GE G+ G+PG+PGP G G PG G RGP G PG G G+G G Sbjct: 1200 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1254 Query: 411 KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469 G G+ G TGP G G G GP G G+PG +G QG G G GPPGP Sbjct: 1255 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1306 Query: 470 GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 GP GLPG +G+ G G G G +G IG G +GE G GLPG G PG+ KG Sbjct: 1307 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1358 Query: 529 EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587 E G+PGA GP GP G G PGP G +G KG+ GP GPKGE G+ GP Sbjct: 1359 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1404 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643 PG PGP G+ P L I+ PK V G R + G PG P Sbjct: 1405 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1451 Query: 644 G 644 G Sbjct: 1452 G 1452 Score = 102 bits (254), Expect = 2e-21 Identities = 81/272 (29%), Positives = 111/272 (40%), Gaps = 76/272 (27%) Query: 542 PGKGQPGPKGDEGKKGSKGNQ---GQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKG 598 P + Q P+ + NQ Q PG E E ++ P + GP G KG Sbjct: 241 PHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLE---EAAHGPRGLKG 297 Query: 599 DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLR 658 ++G P + EPG+ + GP G +GP G+ GP G+ G PGP+ Sbjct: 298 EKGEPAVL----EPGMLVEGPPGPEGPA--------------GLIGPPGIQGNPGPV--- 336 Query: 659 GVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPG-----PPGYGSQG--- 710 G+PG RGPPG +G G G PGPPG P +GS G Sbjct: 337 --------GDPGERGPPGRAGL-----------PGSDGAPGPPGTSLMLPFRFGSGGGDK 377 Query: 711 ---------------------IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKG 748 ++G GP G+ G G +G G PG KGE G+ G G +G Sbjct: 378 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 437 Query: 749 DKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIK 780 +G G PG G++G G G G+ + +K Sbjct: 438 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVK 469 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 441 bits (1135), Expect = e-123 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G GP G G G +G+RGP+G G + KG +G GP G PG +G G +G G Sbjct: 721 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 780 Query: 303 PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 PG KG G PG G +G G QG TGPPG PG G QG GE GP G G PG Sbjct: 781 PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 840 Query: 357 PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414 PG G+QG+ G G+EG G PGP G PG+ GP G G PGERGLPG G PG KG + Sbjct: 841 PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 898 Query: 415 GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460 G GP GP G G G G IGP G GP G PG IG G G+Q Sbjct: 899 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 958 Query: 461 GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497 GP+G PGP GP G +G G+KGE G GP GP GPVG Sbjct: 959 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018 Query: 498 ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534 G +GP+G PG IGL G PG GE G G G G PG Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078 Query: 535 -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586 A GP+GPPG G GP G++G+ G G+ G +G PG +GP+GE G G G P Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138 Query: 587 GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637 G PGPPGPKG +G PG GF G+PG P G GPRG GA G +G+ Sbjct: 1139 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1191 Query: 638 -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680 G PG PGP G GPPGP+G RG GD GA G PG GP GP+GP Sbjct: 1192 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1251 Query: 681 RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720 G VG QG G TGQ G PGP GPPG G G KGE+G G Sbjct: 1252 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1311 Query: 721 ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 PG +G G GLPG +G G++G++G G G IG G PG G GPKG G T Sbjct: 1312 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1369 Score = 439 bits (1129), Expect = e-123 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294 G PG GPPGT GN G G +GP G PG KG GE+G G PG+KGD Sbjct: 584 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 643 Query: 295 GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345 G +G+ G+ G+ G +G GP GPKG TGP GDPGP G G KG+ P Sbjct: 644 GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 697 Query: 346 GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392 G GP GS G PG G G KG RG G+ G G G G GQ GPRG Sbjct: 698 GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 757 Query: 393 ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447 P G PGERGLPG GP G G +GP GP G GL G++G++G G GP G Sbjct: 758 GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 815 Query: 448 IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496 PG+ G+ GE G G G PGP GP G QGLPG+ G+ G G GP G P G Sbjct: 816 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 875 Query: 497 I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543 + G G KG G G PG G PGE GAAG G G PG GP+GPPG Sbjct: 876 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 935 Query: 544 ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589 KG PG KG G G G QG GLPGP GP G E G G G PG Sbjct: 936 AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 995 Query: 590 ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634 PGPPGP G G PG G GEPG RGP +G GP GP+G GL Sbjct: 996 EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1053 Query: 635 KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674 G G PG PGPRG GP G P G+ +G G KGEPG G Sbjct: 1054 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1113 Query: 675 PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733 PG G GV G +G +G+ G+ G PG PGPPG +G G+ GP+G PGP G G PG Sbjct: 1114 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1169 Query: 734 QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772 GE G RG G KGD+GE GE PGSPG G GP G LG Sbjct: 1170 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211 Score = 431 bits (1109), Expect = e-120 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G G G G+PG+KG+RG G PG +KG G+ G G+PG G+ GERG+ G+ Sbjct: 430 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356 G +G G GP G GP+G GI GPPG GPKG G +GEPGPPG G+PG Sbjct: 490 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 549 Query: 357 PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407 G+ G G GE+G +G+PG PG P G PG PG GP G G +G G G+ Sbjct: 550 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 609 Query: 408 PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463 PGP+G KG +G G +G +G G KGDIG G +G +G+P GS+GE G +GP Sbjct: 610 PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 667 Query: 464 GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522 G GP G G PG GE G++G G P P G QGPK GS+G PG PG GE G Sbjct: 668 GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 719 Query: 523 AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573 A G G++G G RGP GP +GQ GP+G GK G+KG G+RGLPGP+GP Sbjct: 720 ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 777 Query: 574 KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602 G PG GP G PG T PGPP GP G+RG Sbjct: 778 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837 Query: 603 PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659 PG PG GE GL G +G +G GP GAPG G G G PG RGLPG G GL+G Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897 Query: 660 ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712 G G+ GE G G GP GP G G QGP G G+KG+PG GP G G Sbjct: 898 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 955 Query: 713 GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G QGP G PGP G G+ G+ G+ GE GD G+KG KG GE G PG G GP G G Sbjct: 956 GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1013 Score = 426 bits (1095), Expect = e-119 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG G G+ GP G+ G+ G++G G G Sbjct: 834 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 891 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347 PG+KG++G GP GP G G +G GPPG PGP KG G KG GP Sbjct: 892 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951 Query: 348 ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385 PGP G PG G GQ+G KG +G+ G PG PGPI G Sbjct: 952 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1009 Query: 386 GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443 GQPG G +G PG RG G G G +G +G GP GP GLQGL GEKG+ G VGP Sbjct: 1010 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1069 Query: 444 GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501 GP G PG G G G GP GPPG G G PG KGE G+ G G +G G+ G +G Sbjct: 1070 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560 +GE G G PG+PG PG G G G G PG G G PG G+ GP+G +G KG +G Sbjct: 1128 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1187 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 G+ G PG GP GE G GP G G PG G +G +G G PG G PG + GP Sbjct: 1188 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1245 Query: 620 KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671 G GP G G GL+G G PG G G PGP GP GL G+ GD GAKGE G Sbjct: 1246 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1305 Query: 672 RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730 G G GP G QG KGD +GLPGP G PG G GI G GP G GP G G Sbjct: 1306 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1360 Query: 731 LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763 G KG G G G KG+KG G PG PG G Sbjct: 1361 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391 Score = 420 bits (1080), Expect = e-117 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279 GDPG+ GPPG G PG G GP G G KG Sbjct: 316 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 375 Query: 280 -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336 RGP G GY G G G+ G PG+KG+ G GP GP+GP QG+TGPPG G + Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 432 Query: 337 -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394 G G +G PG PG G G G+ G G KG RG G G PGP PG+ G RG + Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 487 Query: 395 GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450 G G RGLPGE P GPKG G GP G +G+ G +G KG +GP G GP G G Sbjct: 488 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 545 Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507 G+QG G QG IGP G +GP G+ GLPG G G G G GP G G QGP G G Sbjct: 546 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 605 Query: 508 SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 +G PG GV G DG G+KGE G PG +G G G G PG +G++G +G Sbjct: 606 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 665 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614 KG G G PGP G GE G +G G+PG PG GPKG G PG PG GE G Sbjct: 666 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 723 Query: 615 ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659 GP+G +GPRG G G K GDG G PG RGLPGP GP G G Sbjct: 724 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 783 Query: 660 ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703 G G +GE G +G GP GP G VG QG G+T G++G PGPPGP Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843 Query: 704 PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755 PG G +G KG+ GP G PG G G G PG++G G G G KG++G G Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903 Query: 756 P---GSPGKQGLQGPKGDLG 772 P GSPG++G G G +G Sbjct: 904 PGPAGSPGERGAAGSGGPIG 923 Score = 385 bits (990), Expect = e-107 Identities = 258/633 (40%), Positives = 304/633 (48%), Gaps = 111/633 (17%) Query: 233 KKCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG 292 + CE+K ECE G P H + +R P+ P + + E G +G Sbjct: 219 ESCEQKELECEGGQRERPQNQQPH-----RAQRSPQQQPSRLHRPQNQEPQSQAAHGPRG 273 Query: 293 DKGERGECG--KPG--IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEP--- 345 KGE+GE +PG ++G G GP G GP GIQG GP GDPG +G G G P Sbjct: 274 LKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSD 333 Query: 346 ----------------------------------------------GPPGPYGSPGAPG- 358 GPPGP G G PG Sbjct: 334 GAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGP 393 Query: 359 ---IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG---------- 404 G G+KGE G G G GP G+ G PG+ G RG G G RG+PG Sbjct: 394 LGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGF 453 Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIG 464 +G PG GEKG G TG QGL G GE G+ G G GP G+P G G +G+ GP G Sbjct: 454 DGLPGLPGEKGHRGDTGAQGLPG--PPGEDGERGDDGEIGPRGLP--GESGPRGLLGPKG 509 Query: 465 PPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523 PPG GP G +G+ G +G G +GP G GP G +G PG+ GLPG G G G Sbjct: 510 PPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-----PGQQGTPGTQGLPGPQGAIGPHGE 564 Query: 524 AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582 G +G+ GLPG G +GPPG G+ GP G +G +G G QG G PGP G KG GI G Sbjct: 565 KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 624 Query: 583 FGMPG-------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 G G G G KGDRG G+PG +GE G GPKG GP G G PGL Sbjct: 625 KGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDG--PEGPKGRTGPTGDPGPPGLM 682 Query: 636 GD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-------GTQ 686 G+ G GVPG G PG GP G G G GA GE G RG G SGPRG G + Sbjct: 683 GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742 Query: 687 GPKGDTGQKGL------PGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG 739 GP+G TG+ G GP GPP G +G+ G QGP GFPGPKG G G G G G Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPP--GERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 800 Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 +RG+VG +G G G PG G QG G G +G Sbjct: 801 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 833 Score = 306 bits (785), Expect = 5e-83 Identities = 202/469 (43%), Positives = 237/469 (50%), Gaps = 56/469 (11%) Query: 360 GQQGIKGERGQ----------EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP 408 G +G+KGE+G+ EG PG GP G +G PG G GP G PGERG PG Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA-- 327 Query: 409 GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP--- 465 G G G+ GP G + GD GPV I Q ++GP GP Sbjct: 328 GLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGY 387 Query: 466 PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGE 520 G GP GQ G PG KGE G +GP GPRGP G+ G G +G G+ G G PG PG Sbjct: 388 TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 447 Query: 521 DGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGI 579 G G G GLPG +G G G +G PGP G++G++G G G RGLPG GP+G G Sbjct: 448 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507 Query: 580 MGPFGMPGT----SIPGPPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGP 628 GP G+PG + GP GPKG +G PG PG +G PG + GP+G GP +GP Sbjct: 508 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567 Query: 629 VGAPGLKG----DGYPGVPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGP 677 G PGL G DG PG PG G PG P GP G G G G KG G+RG G Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627 Query: 678 SGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH--- 729 G +G G G KGD G KG G G PG G +G KG GP G PGP G MG Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687 Query: 730 ----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 GLPG G G +G +G G G GE G+ G G GP+G+ G T Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPT 736 Score = 290 bits (741), Expect = 7e-78 Identities = 191/483 (39%), Positives = 241/483 (49%), Gaps = 101/483 (20%) Query: 361 QQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPT 420 Q+ ++ E GQ RP P R P+ P P E S+ Sbjct: 223 QKELECEGGQRERPQNQQP-------HRAQRSPQQQPSRLHRP------QNQEPQSQAAH 269 Query: 421 GPQGLQGLSIKGEKGDI----------GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQG 470 GP+GL KGEKG+ GP GP+GP G+ IG G QG GP+G PG +G Sbjct: 270 GPRGL-----KGEKGEPAVLEPGMLVEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERG 322 Query: 471 PAGQ-GLPGSKGEVGQMGPT-----------GPRGPVGIGVQGP------------KGEP 506 P G+ GLPGS G G G + G +GPV + +G P Sbjct: 323 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382 Query: 507 GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRG 566 G +G G+PG G+ G+ G KGE+G G +GP GP +G GP G G++G G G RG Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP--QGLTGPPGKAGRRGRAGADGARG 440 Query: 567 LPGPEGPKGEPGIMGPFGMPGTS----------IPGPPGPKGDRGGPGIPGFKGEPGLSI 616 +PG G KG+ G G G+PG +PGPPG G+RG G G +G PG S Sbjct: 441 MPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES- 499 Query: 617 RGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVR 672 GP+G+ GP+GP G PG PG RG+ GP GP G G G G +G PG + Sbjct: 500 -GPRGLLGPKGP--------PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 550 Query: 673 GPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFP 721 G PGP G G G +GP+G G G+PG GPPG+ G+QG G QGP G+P Sbjct: 551 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610 Query: 722 GPKGTMG----HGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 GP+G G GL G KGE GE +GD+G KGD+GE+G PGS G+ G +GPKG Sbjct: 611 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 670 Query: 772 GLT 774 G T Sbjct: 671 GPT 673 Score = 288 bits (737), Expect = 2e-77 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292 EKG+ GD PGPPG G G G GP+G PG GE GE G G PG +G Sbjct: 1059 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1118 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 + G +G G+ G KG+ G PG GP GP+G G GP G+PGP GF G+ G PG GP G Sbjct: 1119 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178 Query: 353 SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410 GA +G +GE G+ G+PG+PGP G G PG G RGP G PG G G+G G Sbjct: 1179 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1233 Query: 411 KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469 G G+ G TGP G G G GP G G+PG +G QG G G GPPGP Sbjct: 1234 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1285 Query: 470 GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 GP GLPG +G+ G G G G +G IG G +GE G GLPG G PG+ KG Sbjct: 1286 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1337 Query: 529 EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587 E G+PGA GP GP G G PGP G +G KG+ GP GPKGE G+ GP Sbjct: 1338 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1383 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643 PG PGP G+ P L I+ PK V G R + G PG P Sbjct: 1384 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1430 Query: 644 G 644 G Sbjct: 1431 G 1431 Score = 101 bits (252), Expect = 3e-21 Identities = 68/195 (34%), Positives = 90/195 (46%), Gaps = 48/195 (24%) Query: 618 GPKGVQGPRGP--VGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675 GP+G++G +G V PG+ +G PG GP GL GPPG G + G G+PG RGPP Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG-----NPGPVGDPGERGPP 324 Query: 676 GPSGPRGVGTQGPKGDTGQKGLPGPPG-----PPGYGSQG-------------------- 710 G +G G G PGPPG P +GS G Sbjct: 325 GRAGL-----------PGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 373 Query: 711 ----IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765 ++G GP G+ G G +G G PG KGE G+ G G +G +G G PG G++G Sbjct: 374 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRA 433 Query: 766 GPKGDLGLTKEEIIK 780 G G G+ + +K Sbjct: 434 GADGARGMPGDPGVK 448 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 441 bits (1135), Expect = e-123 Identities = 285/658 (43%), Positives = 326/658 (49%), Gaps = 136/658 (20%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G GP G G G +G+RGP+G G + KG +G GP G PG +G G +G G Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGF 887 Query: 303 PGIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 PG KG G PG G +G G QG TGPPG PG G QG GE GP G G PG Sbjct: 888 PGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGP 947 Query: 357 PGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGPKGEK 414 PG G+QG+ G G+EG G PGP G PG+ GP G G PGERGLPG G PG KG + Sbjct: 948 PGPPGEQGLPGTAGKEGTKGDPGPPGA--PGKDGPAGLRGFPGERGLPGTAGGPGLKGNE 1005 Query: 415 GSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPG-------------IGSQGEQGIQ 460 G GP GP G G G G IGP G GP G PG IG G G+Q Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQ 1065 Query: 461 GPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRGPVGI------- 497 GP+G PGP GP G +G G+KGE G GP GP GPVG Sbjct: 1066 GPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125 Query: 498 ---GVQGPKGE---------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPG----- 534 G +GP+G PG IGL G PG GE G G G G PG Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185 Query: 535 -------ARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMP 586 A GP+GPPG G GP G++G+ G G+ G +G PG +GP+GE G G G P Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245 Query: 587 GTSIPGPPGPKGD------RGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD--- 637 G PGPPGPKG +G PG GF G+PG P G GPRG GA G +G+ Sbjct: 1246 GE--PGPPGPKGPTGDDGPKGNPGPVGFPGDPG-----PPGEGGPRGQDGAKGDRGEDGE 1298 Query: 638 -GYPGVPGPRGLPGPPGPMGLRGV----------------GDTGAKGEPGVRGPPGPSGP 680 G PG PGP G GPPGP+G RG GD GA G PG GP GP+GP Sbjct: 1299 PGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGP 1358 Query: 681 RG-------------VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGF--- 720 G VG QG G TGQ G PGP GPPG G G KGE+G G Sbjct: 1359 AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGL 1418 Query: 721 ---PGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 PG +G G GLPG +G G++G++G G G IG G PG G GPKG G T Sbjct: 1419 IGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGAT 1476 Score = 439 bits (1129), Expect = e-123 Identities = 285/642 (44%), Positives = 318/642 (49%), Gaps = 128/642 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG----------NAQKGEAGERGPGGIPGYKGDK 294 G PG GPPGT GN G G +GP G PG KG GE+G G PG+KGD Sbjct: 691 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 750 Query: 295 GERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---------P 345 G +G+ G+ G+ G +G GP GPKG TGP GDPGP G G KG+ P Sbjct: 751 GVKGDRGEVGVPGSRGEDGPEGPKGR------TGPTGDPGPPGLMGEKGKLGVPGLPGYP 804 Query: 346 GPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG----------- 392 G GP GS G PG G G KG RG G+ G G G G GQ GPRG Sbjct: 805 GRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTS 864 Query: 393 ----PEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMG 447 P G PGERGLPG GP G G +GP GP G GL G++G++G G GP G Sbjct: 865 GGDGPHGPPGERGLPGP--QGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPG 922 Query: 448 IPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG------PVG 496 PG+ G+ GE G G G PGP GP G QGLPG+ G+ G G GP G P G Sbjct: 923 PPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG 982 Query: 497 I-------------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543 + G G KG G G PG G PGE GAAG G G PG GP+GPPG Sbjct: 983 LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 1042 Query: 544 ----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG---EPGIMGPFGMPGTS------- 589 KG PG KG G G G QG GLPGP GP G E G G G PG Sbjct: 1043 AAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1102 Query: 590 ---IPGPPGPKGDRGGPGIPGFKGEPGLSIRGP------------KGVQGPRGPVGAPGL 634 PGPPGP G G PG G GEPG RGP +G GP GP+G GL Sbjct: 1103 EHGPPGPPGPIGPVGQPGAAGADGEPGA--RGPQGHFGAKGDEGTRGFNGPPGPIGLQGL 1160 Query: 635 KGD-------------GYPGVPGPRGLPGPPG-------PMGLRGVGDTGAKGEPGVRGP 674 G G PG PGPRG GP G P G+ +G G KGEPG G Sbjct: 1161 PGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGS 1220 Query: 675 PGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPG 733 PG G GV G +G +G+ G+ G PG PGPPG +G G+ GP+G PGP G G PG Sbjct: 1221 PGIQGEPGVKGPRGERGEKGESGQPGEPGPPG--PKGPTGDDGPKGNPGPVGFPGD--PG 1276 Query: 734 QKGEHGERGDVGKKGDKGEIGE---PGSPGKQGLQGPKGDLG 772 GE G RG G KGD+GE GE PGSPG G GP G LG Sbjct: 1277 PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1318 Score = 431 bits (1109), Expect = e-120 Identities = 271/600 (45%), Positives = 321/600 (53%), Gaps = 87/600 (14%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGK 302 +G G G G G+PG+KG+RG G PG +KG G+ G G+PG G+ GERG+ G+ Sbjct: 537 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPG------DPGPKGFQGNKGEPGPPGPYGSPGA 356 G +G G GP G GP+G GI GPPG GPKG G +GEPGPPG G+PG Sbjct: 597 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGT 656 Query: 357 PGI----GQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEGVPGERGLPGE----GF 407 G+ G G GE+G +G+PG PG P G PG PG GP G G +G G G+ Sbjct: 657 QGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGY 716 Query: 408 PGPKGEKGSEGPTGPQGLQGL----SIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPI 463 PGP+G KG +G G +G +G G KGDIG G +G +G+P GS+GE G +GP Sbjct: 717 PGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVP--GSRGEDGPEGPK 774 Query: 464 GPPGPQGPAGQGLPGSKGEVGQMGPTG-PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDG 522 G GP G G PG GE G++G G P P G QGPK GS+G PG PG GE G Sbjct: 775 GRTGPTGDPGP--PGLMGEKGKLGVPGLPGYP---GRQGPK---GSLGFPGFPGASGEKG 826 Query: 523 AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ---------GQRGLPGPEGP 573 A G G++G G RGP GP +GQ GP+G GK G+KG G+RGLPGP+GP Sbjct: 827 ARGLSGKSGPRGERGPTGP--RGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884 Query: 574 KGEPGIMGPFGMPG-------------------TSIPGPP------------GPKGDRGG 602 G PG GP G PG T PGPP GP G+RG Sbjct: 885 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944 Query: 603 PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659 PG PG GE GL G +G +G GP GAPG G G G PG RGLPG G GL+G Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004 Query: 660 ------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712 G G+ GE G G GP GP G G QGP G G+KG+PG GP G G Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP--IGPTGRD 1062 Query: 713 GEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G QGP G PGP G G+ G+ G+ GE GD G+KG KG GE G PG G GP G G Sbjct: 1063 GVQGPVGLPGPAGP--PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPG 1120 Score = 426 bits (1095), Expect = e-119 Identities = 263/573 (45%), Positives = 300/573 (52%), Gaps = 67/573 (11%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 E+G PG PGPPG G PG G+ G KG+PG G G+ GP G+ G+ G++G G G Sbjct: 941 ERGHPGPPGPPGEQGLPGTAGKEGTKGDPG--PPGAPGKDGPAGLRGFPGERGLPGTAGG 998 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGIT------GPPGDPGP---------KGFQGNKGEPGP 347 PG+KG++G GP GP G G +G GPPG PGP KG G KG GP Sbjct: 999 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058 Query: 348 ------------PGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEP 385 PGP G PG G GQ+G KG +G+ G PG PGPI G Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI--GPV 1116 Query: 386 GQPGPRGPEGVPGERGLPGE-GFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQ 443 GQPG G +G PG RG G G G +G +G GP GP GLQGL GEKG+ G VGP Sbjct: 1117 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1176 Query: 444 GPMGIPG-IGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI-GVQG 501 GP G PG G G G GP GPPG G G PG KGE G+ G G +G G+ G +G Sbjct: 1177 GPPGPPGPRGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKG 560 +GE G G PG+PG PG G G G G PG G G PG G+ GP+G +G KG +G Sbjct: 1235 ERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRG 1294 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 G+ G PG GP GE G GP G G PG G +G +G G PG G PG + GP Sbjct: 1295 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKT--GP 1352 Query: 620 KGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGV 671 G GP G G GL+G G PG G G PGP GP GL G+ GD GAKGE G Sbjct: 1353 VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGH 1412 Query: 672 RGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHG 730 G G GP G QG KGD +GLPGP G PG G GI G GP G GP G G Sbjct: 1413 PGLIGLIGP--PGEQGEKGD---RGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPA 1467 Query: 731 LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQG 763 G KG G G G KG+KG G PG PG G Sbjct: 1468 --GPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498 Score = 420 bits (1080), Expect = e-117 Identities = 269/620 (43%), Positives = 312/620 (50%), Gaps = 104/620 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNP---------GNAQKGEA---------------- 279 GDPG+ GPPG G PG G GP G G KG Sbjct: 423 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 482 Query: 280 -GERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-- 336 RGP G GY G G G+ G PG+KG+ G GP GP+GP QG+TGPPG G + Sbjct: 483 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP---QGLTGPPGKAGRRGR 539 Query: 337 -GFQGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPE 394 G G +G PG PG G G G+ G G KG RG G G PGP PG+ G RG + Sbjct: 540 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP-----PGEDGERGDD 594 Query: 395 GVPGERGLPGEGFP----GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450 G G RGLPGE P GPKG G GP G +G+ G +G KG +GP G GP G G Sbjct: 595 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQG 652 Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507 G+QG G QG IGP G +GP G+ GLPG G G G G GP G G QGP G G Sbjct: 653 TPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQG 712 Query: 508 SIGLPGQPGVPGEDGA------AGKKGEAGLPGARGPEGPPGK----GQPGPKGDEGKKG 557 +G PG GV G DG G+KGE G PG +G G G G PG +G++G +G Sbjct: 713 PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG 772 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL--- 614 KG G G PGP G GE G +G G+PG PG GPKG G PG PG GE G Sbjct: 773 PKGRTGPTGDPGPPGLMGEKGKLGVPGLPG--YPGRQGPKGSLGFPGFPGASGEKGARGL 830 Query: 615 ----------SIRGPKGVQGPRGPVGAPGLK----GDGYPGVPGPRGLPGPPGPMGLRG- 659 GP+G +GPRG G G K GDG G PG RGLPGP GP G G Sbjct: 831 SGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890 Query: 660 ------------VGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDT---GQKGLPGPPGP 703 G G +GE G +G GP GP G VG QG G+T G++G PGPPGP Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950 Query: 704 PG-------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGE 755 PG G +G KG+ GP G PG G G G PG++G G G G KG++G G Sbjct: 951 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010 Query: 756 P---GSPGKQGLQGPKGDLG 772 P GSPG++G G G +G Sbjct: 1011 PGPAGSPGERGAAGSGGPIG 1030 Score = 373 bits (958), Expect = e-103 Identities = 252/600 (42%), Positives = 292/600 (48%), Gaps = 109/600 (18%) Query: 264 ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG--IKGDKGSPGPYGPKGPR 321 E GP + A G A GP G+ KG+KGE +PG ++G G GP G GP Sbjct: 359 ELGPALSAETAHSGAAAH-GPRGL---KGEKGEPAVL-EPGMLVEGPPGPEGPAGLIGPP 413 Query: 322 GIQGITGPPGDPGPKGFQGNKGEP------------------------------------ 345 GIQG GP GDPG +G G G P Sbjct: 414 GIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQ 473 Query: 346 -------------GPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIGV-GEPGQ 387 GPPGP G G PG G G+KGE G G G GP G+ G PG+ Sbjct: 474 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 533 Query: 388 PGPRGPEGVPGERGLPG----------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI 437 G RG G G RG+PG +G PG GEKG G TG QGL G GE G+ Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG--PPGEDGER 591 Query: 438 GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG 496 G G GP G+P G G +G+ GP GPPG GP G +G+ G +G G +GP G GP Sbjct: 592 GDDGEIGPRGLP--GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP-- 647 Query: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGK 555 G +G PG+ GLPG G G G G +G+ GLPG G +GPPG G+ GP G +G Sbjct: 648 ---PGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 704 Query: 556 KGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGF 608 +G G QG G PGP G KG GI G G G G G KGDRG G+PG Sbjct: 705 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGS 764 Query: 609 KGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAK 666 +GE G GPKG GP G G PGL G+ G GVPG G PG GP G G G GA Sbjct: 765 RGEDG--PEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGAS 822 Query: 667 GEPGVRGPPGPSGPRGV-------GTQGPKGDTGQKGL------PGPPGPPGYGSQGIKG 713 GE G RG G SGPRG G +GP+G TG+ G GP GPP G +G+ G Sbjct: 823 GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP--GERGLPG 880 Query: 714 EQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 QGP GFPGPKG G G G G G+RG+VG +G G G PG G QG G G +G Sbjct: 881 PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMG 940 Score = 310 bits (793), Expect = 6e-84 Identities = 214/512 (41%), Positives = 252/512 (49%), Gaps = 63/512 (12%) Query: 324 QGITGPPGDPGPK--GFQGNKGEPGPPGPYGSP-----GAPGIGQQGIKGERGQ------ 370 +G T PP P G+ + E GP S GA G +G+KGE+G+ Sbjct: 334 EGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEP 393 Query: 371 ----EGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGL 425 EG PG GP G +G PG G GP G PGERG PG G G G+ GP G + Sbjct: 394 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRA--GLPGSDGAPGPPGTSLM 451 Query: 426 QGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGP---PGPQGPAGQ-GLPGSKG 481 GD GPV I Q ++GP GP G GP GQ G PG KG Sbjct: 452 LPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKG 511 Query: 482 EVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARG 537 E G +GP GPRGP G+ G G +G G+ G G PG PG G G G GLPG +G Sbjct: 512 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 571 Query: 538 PEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT----SIPG 592 G G +G PGP G++G++G G G RGLPG GP+G G GP G+PG + G Sbjct: 572 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 631 Query: 593 PPGPKGD---RGGPGIPGFKGEPGLS-IRGPKGVQGP---RGPVGAPGLKG----DGYPG 641 P GPKG +G PG PG +G PG + GP+G GP +GP G PGL G DG PG Sbjct: 632 PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 691 Query: 642 VPGPRGLPG------PPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTG 693 PG G PG P GP G G G G KG G+RG G G +G G G KGD G Sbjct: 692 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG 751 Query: 694 QKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-------GLPGQKGEHGERG 742 KG G G PG G +G KG GP G PGP G MG GLPG G G +G Sbjct: 752 VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 811 Query: 743 DVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 +G G G GE G+ G G GP+G+ G T Sbjct: 812 SLGFPGFPGASGEKGARGLSGKSGPRGERGPT 843 Score = 288 bits (737), Expect = 2e-77 Identities = 183/421 (43%), Positives = 214/421 (50%), Gaps = 67/421 (15%) Query: 243 EKGDPGD------PGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKG 292 EKG+ GD PGPPG G G G GP+G PG GE GE G G PG +G Sbjct: 1166 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1225 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 + G +G G+ G KG+ G PG GP GP+G G GP G+PGP GF G+ G PG GP G Sbjct: 1226 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1285 Query: 353 SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP-GEGFPGP 410 GA +G +GE G+ G+PG+PGP G G PG G RGP G PG G G+G G Sbjct: 1286 QDGA-----KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGD 1340 Query: 411 KGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469 G G+ G TGP G G G GP G G+PG +G QG G G GPPGP Sbjct: 1341 PGAIGAPGKTGP--------VGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPV 1392 Query: 470 GPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG 528 GP GLPG +G+ G G G G +G IG G +GE G GLPG G PG+ KG Sbjct: 1393 GP--PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ------KG 1444 Query: 529 EAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587 E G+PGA GP GP G G PGP G +G KG+ GP GPKGE G+ GP Sbjct: 1445 EMGIPGASGPIGPGGPPGLPGPAGPKGAKGA---------TGPGGPKGEKGVQGP----- 1490 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK----GVQGPRGPVGAPGLKGDGYPGVP 643 PG PGP G+ P L I+ PK V G R + G PG P Sbjct: 1491 ---PGHPGPPGEVIQP----------LPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSP 1537 Query: 644 G 644 G Sbjct: 1538 G 1538 Score = 288 bits (736), Expect = 3e-77 Identities = 189/467 (40%), Positives = 235/467 (50%), Gaps = 94/467 (20%) Query: 383 GEPGQPGPRGPE----GVPGERGLPGEGFPGPKGEKGSEGPT--GPQGLQGLSIKGEKGD 436 GE G P GP G + E P E G GP+GL KGEKG+ Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGL-----KGEKGE 387 Query: 437 I----------GPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQ 485 GP GP+GP G+ IG G QG GP+G PG +GP G+ GLPGS G G Sbjct: 388 PAVLEPGMLVEGPPGPEGPAGL--IGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGP 445 Query: 486 MGPT-----------GPRGPVGIGVQGP------------KGEPGSIGLPGQPGVPGEDG 522 G + G +GPV + +G PG +G G+PG G+ G Sbjct: 446 PGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPG 505 Query: 523 AAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582 + G KGE+G G +GP GP +G GP G G++G G G RG+PG G KG+ G G Sbjct: 506 SPGLKGESGDLGPQGPRGP--QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 563 Query: 583 FGMPGTS----------IPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632 G+PG +PGPPG G+RG G G +G PG S GP+G+ GP+GP Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGES--GPRGLLGPKGP---- 617 Query: 633 GLKGDGYPGVPGPRGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-GTQG 687 G PG PG RG+ GP GP G G G G +G PG +G PGP G G G +G Sbjct: 618 ----PGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673 Query: 688 PKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPGPKGTMG----HGLPG 733 P+G G G+PG GPPG+ G+QG G QGP G+PGP+G G GL G Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKG 733 Query: 734 QKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 KGE GE +GD+G KGD+GE+G PGS G+ G +GPKG G T Sbjct: 734 HKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780 Score = 238 bits (606), Expect = 3e-62 Identities = 173/423 (40%), Positives = 202/423 (47%), Gaps = 72/423 (17%) Query: 412 GEKGSEGPTGPQGLQ-------------GLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQG 458 GE G++ P GP G ++ E G GP G+ G +GE Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAA-HGPRGLKG--EKGEPA 389 Query: 459 IQGP----IGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPG 513 + P GPPGP+GPAG G PG +G G +G G RGP G G PGS G PG Sbjct: 390 VLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP-----PGRAGLPGSDGAPG 444 Query: 514 QPG----VPGEDGAAG-----------KKGEAGLPGAR----GPEGPPG-KGQPGPKGDE 553 PG +P G+ G + +A L AR GP GP G G+PGP G Sbjct: 445 PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 504 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIP 606 G G KG G G GP GP+G G G G G + +PG PG KGDRG G+P Sbjct: 505 GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 564 Query: 607 GFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAK 666 G GE G RG G QG GP G G +GD G GPRGLPG GP GL G K Sbjct: 565 GLPGEKGH--RGDTGAQGLPGPPGEDGERGDD--GEIGPRGLPGESGPRGL-----LGPK 615 Query: 667 GEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKG 725 G PG+ GPPG G G QGPKG G +G PGPPG G G+QG+ G QG G G KG Sbjct: 616 GPPGIPGPPGVRGMDG--PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKG 673 Query: 726 TMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITE 784 G GLPG G G G GK+G PG+ G QG GP+G LG +K + Sbjct: 674 PQGKPGLPGMPGSDGPPGHPGKEGP------PGTKGNQGPSGPQGPLGYPGPRGVKGVDG 727 Query: 785 ICG 787 I G Sbjct: 728 IRG 730 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 435 bits (1119), Expect = e-121 Identities = 291/683 (42%), Positives = 342/683 (50%), Gaps = 163/683 (23%) Query: 244 KGDPGDPG-----------PPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKG 292 +GD GDPG PPG G+PG+ G++G G+P G G+RG G+PG KG Sbjct: 724 RGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKG 783 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP------KGFQGNKGEPG 346 RG+ G PG +G G PG G KGP+G +G G PG PGP +G G G+PG Sbjct: 784 P---RGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPG 840 Query: 347 PPGPYGSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGV----------GEPG 386 PG GSPGAPG G G+KG G GRPGA GP G+ G PG Sbjct: 841 LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPG 900 Query: 387 QPGPRGPEGVPG------ERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGP 439 PGP+GP G+PG ERG PG EG PG KGE G +G +G G +GL +G KG IGP Sbjct: 901 PPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGL--RGAKGAIGP 958 Query: 440 VGPQGPM------------------GIPGI-GSQGEQGIQGPIGPPGPQGPAG--QGLPG 478 G +G M G PG G +G G+QG G PG GP G +G PG Sbjct: 959 PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPG 1018 Query: 479 SKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAG 531 KG+ G GP GP G G+ G+ G +GEPGS PG PG G DGA G KG G Sbjct: 1019 EKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS---PGPPGFSGIDGARGPKGNKG 1075 Query: 532 LP----GARGPEGPPGK----GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPF 583 P G GP+G PG G G G++G G +G +G G PGP G G PG G Sbjct: 1076 DPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDH 1135 Query: 584 GMPGT-------SIPGPPGPKGDRGGPGIPGFKG---EPGLS----IRGPKGVQG----- 624 GMPG PGP G +GD G PG PG KG PGL+ ++G KG +G Sbjct: 1136 GMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLH 1195 Query: 625 ---PRGPVGAPGLKGD----GYPGV--PGPRGLPGPPGPMGLRGV-GDTGAKGE------ 668 P GPVG PGLKG+ G PG+ PGPRG GPPGP G G G GA G Sbjct: 1196 DVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIP 1255 Query: 669 ----PGVRGPPGPSGPRGV--------------GTQGPKGDTGQKGLPGPPGPPGY---- 706 PG +GPPGP GPRG G G G G G PGPPGPPGY Sbjct: 1256 DPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFP 1315 Query: 707 GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGE----------- 755 G G G++GP GFPGP+G HG PG GE G G G+KG G G Sbjct: 1316 GCDGKDGQKGPVGFPGPQGP--HGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVD 1373 Query: 756 -----PGSPGKQGLQGPKGDLGL 773 PG PG G++GP+G +GL Sbjct: 1374 DCPRIPGLPGAPGMRGPEGAMGL 1396 Score = 424 bits (1089), Expect = e-118 Identities = 281/664 (42%), Positives = 326/664 (49%), Gaps = 146/664 (21%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQ----------KGEAGERGPGGIPGYKGDK 294 G GDPGPPG G PG+ G+ G G PGN KG GERGP G PG+ G Sbjct: 524 GTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQP 583 Query: 295 GERGECGKPGIKGDKGSPGPY--GPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 G G G G KGD G PG + G +G G GPPG GP G G G PGPPG G Sbjct: 584 GSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPGERG 642 Query: 353 SPGAPGI----GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGF 407 PG PG G G+KG++G P G PG GP GP+G PG +G PG G Sbjct: 643 HPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGS 702 Query: 408 PGPKGEKGSEGPT---GPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQ 460 G KG G+ G GP G +G GEKG PVGP GP G PG+ G++GI Sbjct: 703 DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGS-SPVGPPGPPGSPGVN--GQKGIP 759 Query: 461 GP-----IGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGL 511 G +GPPG +G +G +PG KG G G G GP GI G++GPKG G G Sbjct: 760 GDPAFGHLGPPGKRGLSG--VPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGF 817 Query: 512 PGQPGVPG---EDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGL 567 PG PG PG E GA G G+ GLPG G G PG KGQPG G G G KG G G Sbjct: 818 PGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGR 877 Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGF---------------KGEP 612 PG GP G PGI GPFG G +PGPPGPKG RG PG PGF KGEP Sbjct: 878 PGAHGPPGLPGIPGPFGDDG--LPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEP 935 Query: 613 G----LSIRGPKGVQGPRGPVGAPGLKG-------------------DGYPGV------- 642 G + G +G++G +G +G PG +G DG+PG Sbjct: 936 GEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTP 995 Query: 643 ---------------------------PGPRGLPGPPGPMGLRGV----GDTGAKGEPGV 671 PGP G PGPPG GLRG G G +GEPG Sbjct: 996 GMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGS 1055 Query: 672 RGPPGPSGPRGV-GTQGPKGDT-------GQKGLPGPPGPPGY----GSQGIKGEQGPQG 719 GPPG SG G G +G KGD G KG PG PG PG+ G QG+ G QGP+G Sbjct: 1056 PGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRG 1115 Query: 720 FPG---PKGTMG-------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769 PG P G+ G HG+PG +G+ GE GD G +G + G+PG PG G++GP G Sbjct: 1116 SPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQ---GDPGIPGPPGIKGPSG 1172 Query: 770 DLGL 773 GL Sbjct: 1173 SPGL 1176 Score = 417 bits (1072), Expect = e-116 Identities = 269/598 (44%), Positives = 305/598 (51%), Gaps = 81/598 (13%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 KG PG PG PG HG PG+ G GP G+ G G G +GP G+PG+ G GERG+ G Sbjct: 869 KGLPGLPGRPGAHGPPGLPGIPGPFGDDG--LPGPPGPKGPRGLPGFPGFPGERGKPGAE 926 Query: 304 GIKGDKGSPGPYG------PKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 G G KG PG G +G RG +G GPPGD G KG PG PGP G G P Sbjct: 927 GCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFP 986 Query: 358 GI-GQQGIKGERGQEGRPGAPGPIGV-----GEPGQPGPRGPEGVPGERGLPG----EGF 407 G G +G G +G+ G PG GP G GE GQPGP GP G PG GL G G Sbjct: 987 GERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGL 1046 Query: 408 PGPKGEKGSEGPTGPQGLQGL-SIKGEKGD----IGPVGPQGPMGIPGI-------GSQG 455 PG +GE GS GP G G+ G KG KGD GP GP+G G PG G QG Sbjct: 1047 PGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQG 1106 Query: 456 EQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE 505 GIQGP G PG GP G G+PG +G+ G+MG GPRG +QG G Sbjct: 1107 LPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRG-----LQGDPGI 1161 Query: 506 PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPE--GPPGK-GQPGPKGDEGKKGSKG-- 560 PG G+ G G PG +G G KG+ G GA G GPPG G PG KG+ G GS G Sbjct: 1162 PGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGIS 1221 Query: 561 ---NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP--------GPPGPKGDRGGPGIPGF- 608 +G++G PGP G G PG G G IP GPPGP G RG PG PG Sbjct: 1222 PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLP 1281 Query: 609 ------KGEPG-LSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV 660 +GEPG + GP G GP GP G G G DG G GP G PGP GP G G Sbjct: 1282 GSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGP 1341 Query: 661 -GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ----KGLPGPPGPPG-YGSQGIKGE 714 G+ G G PG +GP G GPRG GP D GLPG PG G G+ G+ G Sbjct: 1342 PGEKGLPGPPGRKGPTGLPGPRG--EPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGM 1399 Query: 715 QGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 +GP G PG KG G L G++G G G G G KG+ GE G PG G GP GD G Sbjct: 1400 RGPSG-PGCKGEPG--LDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPG 1454 Score = 409 bits (1052), Expect = e-114 Identities = 271/648 (41%), Positives = 317/648 (48%), Gaps = 139/648 (21%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKG---NPGNAQKGEAGERGPGGIPGYKGDKGERG-- 298 KG PGDPG PG +G G G GP G PG A G G GP G PG G GE G Sbjct: 366 KGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIP 425 Query: 299 --------ECGKPGIKGDKGSPG------------PYGPKGPRGIQGITGPPGDPGPKGF 338 + GKPG G G+PG G GP+GI+G GPPG GPKG Sbjct: 426 GRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGE 485 Query: 339 QGNKG----EPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGP 393 +GN+G EPGP GP G PG PG +QG KG+ G PG +G G+PG PG GP Sbjct: 486 KGNEGLCACEPGPMGPPGPPGLPG--RQGSKGDLG------LPGWLGTKGDPGPPGAEGP 537 Query: 394 EGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGS 453 G+PG+ G G PG KG KG + +KG KG+ GP GP G G PG S Sbjct: 538 PGLPGKHGASGP--PGNKGAKGD--------MVVSRVKGHKGERGPDGPPGFPGQPG--S 585 Query: 454 QGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGP---TGPRGPVGIGVQGPKGEPGSIG 510 G G G G PGP G PG KG G +GP GP GP G+G GP GE G G Sbjct: 586 HGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPG 645 Query: 511 LPGQPGVPGEDGAAGKKGEA-----GLPGARGP---EGPPG-KGQPGPKGDEGKKGSKGN 561 +PG PGV G DG G+KG+ PG GP +GPPG KG PGP+G G GS G+ Sbjct: 646 VPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGH 705 Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPG------TSIPGPPGPKGDRGGPGIPGFKGEPGLS 615 +G+ G PG G PG G G PG +S GPPGP G G G G G+P Sbjct: 706 KGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFG 765 Query: 616 IRGPKG---------VQGPRGPVGAPGLKGD-------------------GYPGVPGP-- 645 GP G ++GPRG G PG +G G+PGVPGP Sbjct: 766 HLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPG 825 Query: 646 ----RGLPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV-------GTQGPKG 690 RG PG PG GL G G G KG+PG GPPGP+G +G+ G GP G Sbjct: 826 HSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPG 885 Query: 691 ------DTGQKGLPGPPGP------PGY-GSQGIKGEQGPQGFPGPKGTMGH----GLPG 733 G GLPGPPGP PG+ G G +G+ G +G PG KG G GLPG Sbjct: 886 LPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPG 945 Query: 734 QKGEHGERGDVGKKGDKGEI---------GEPGSPGKQGLQGPKGDLG 772 +G G +G +G GD+GE+ GEPG PG G G +GD G Sbjct: 946 DRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993 Score = 404 bits (1038), Expect = e-112 Identities = 259/615 (42%), Positives = 310/615 (50%), Gaps = 106/615 (17%) Query: 242 CEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPG---YKGDKGERG 298 C PG GPPG G PG KG GP+G PG + G G +G G PG G G RG Sbjct: 668 CNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLS--GSDGHKGRPGTPGTAEIPGPPGFRG 725 Query: 299 ECGKPGIKGDKGSP--GPYGPKGPRGIQGITGPPGDP-----GPKGFQGNKGEPGPPGPY 351 + G PG G+KGS GP GP G G+ G G PGDP GP G +G G PG GP Sbjct: 726 DMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPR 785 Query: 352 GSPGAPG----------IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401 G PG PG +G +G KG G G PG PGP PG RG G+PG+ G Sbjct: 786 GDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGP-----PGHSCERGAPGIPGQPG 840 Query: 402 LPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGE 456 LPG G PG KG+ G GP GP G++GL G G G GP G+PGI G G+ Sbjct: 841 LPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLP-----GLPGRPGAHGPPGLPGIPGPFGD 895 Query: 457 QGIQGPIGPPGPQG-------------PAGQGLPGSKGEVGQMGPTGPRGPVGI----GV 499 G+ GP GP GP+G P +G PG+KGE G+ G +G G G+ G Sbjct: 896 DGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGA 955 Query: 500 QGPKGEPGSI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDE 553 GP G+ G + G PG+PG PG+DG G++G+ G PG +G G PG+ GP G Sbjct: 956 IGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRY--GPPGFH 1013 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 +G G +GQ G PGP GP G G+ G G PG PG +G+ G PG PGF G G Sbjct: 1014 --RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGL-----PGDQGEPGSPGPPGFSGIDG 1066 Query: 614 LSIRGPKGVQG-------PRGPVGAPGLKG----------DGYPGVPGPRGLPGPPGPMG 656 RGPKG +G P GP G PG G G PG+ GPRG PG PGP G Sbjct: 1067 A--RGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPG 1124 Query: 657 LRGV-GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGE 714 G G G G PG+RG PG +G GP+G G G+PGPPG G GS G+ G Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGE-----MGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGL 1179 Query: 715 QGPQGFPGPKGTMGH---------GLPGQKGEHGERGDVG--KKGDKGEIGEPGSPGKQG 763 G +G G KG G G+PG KGE G+ G G G +G+ G PG PG G Sbjct: 1180 HGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSG 1239 Query: 764 LQGPKGDLGLTKEEI 778 GP G G ++I Sbjct: 1240 PPGPAGATGRAPKDI 1254 Score = 401 bits (1031), Expect = e-111 Identities = 268/650 (41%), Positives = 313/650 (48%), Gaps = 136/650 (20%) Query: 243 EKGDPGDPGPPGT-----------------------HGNPGIKGERGPKGNPG----NAQ 275 E+G PG PG PG HG PG G GPKG PG Sbjct: 640 ERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGL 699 Query: 276 KGEAGERGPGGIPG---YKGDKGERGECGKPGIKGDKGSP--GPYGPKGPRGIQGITGPP 330 G G +G G PG G G RG+ G PG G+KGS GP GP G G+ G G P Sbjct: 700 SGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIP 759 Query: 331 GDP-----GPKGFQGNKGEPGPPGPYGSPGAPG----------IGQQGIKGERGQEGRPG 375 GDP GP G +G G PG GP G PG PG +G +G KG G G PG Sbjct: 760 GDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPG 819 Query: 376 APGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIK 431 PGP PG RG G+PG+ GLPG G PG KG+ G GP GP G++GL Sbjct: 820 VPGP-----PGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL--- 871 Query: 432 GEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQG-------------PAGQGLP 477 G G G GP G+PGI G G+ G+ GP GP GP+G P +G P Sbjct: 872 --PGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCP 929 Query: 478 GSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSI------GLPGQPGVPGEDGAAGKK 527 G+KGE G+ G +G G G+ G GP G+ G + G PG+PG PG+DG G++ Sbjct: 930 GAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGER 989 Query: 528 GEAGLPGARGPEGPPG--------------KGQPGPKGDEGKKGSKGNQGQRGLPGPEGP 573 G+ G PG +G G PG KGQPGP G G GS G +G G PG G Sbjct: 990 GDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGD 1049 Query: 574 KGEPGIMGPFGMPG--------------TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 +GEPG GP G G S GPPGPKG+ G PG PG G G +G Sbjct: 1050 QGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASG--EQGL 1107 Query: 620 KGVQGPRGPVGAPGLKG-DGYPGVPGPRGLP---------GPPGPMGLRGVGDTGAKGEP 669 G+QGPRG G PG G G PG PG G+P G PGP GL+ GD G G P Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQ--GDPGIPGPP 1165 Query: 670 GVRGPPGPSGPRGV-GTQGPKGDTGQKGL--PGPPGPPGYGSQGIKGEQGPQGFPG--PK 724 G++GP G G G+ G +G KG G GL GPPGP G G+KGE+G G PG P Sbjct: 1166 GIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP--VGIPGLKGERGDPGSPGISPP 1223 Query: 725 GTMG-HGLPGQKGEHGERGDVGKKG-DKGEIGEPGSPGKQGLQGPKGDLG 772 G G G PG G G G G G +I +PG PG QG GP G G Sbjct: 1224 GPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRG 1273 Score = 392 bits (1008), Expect = e-109 Identities = 281/711 (39%), Positives = 329/711 (46%), Gaps = 187/711 (26%) Query: 239 ICEC--EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE 296 +C C EKG G PGPPG G G G GP G G +KG G+RGP G G KGDKG Sbjct: 54 VCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSG--EKGMRGDRGPPGAAGDKGDKGP 111 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG+ G G PGP GP+G G+ G G GDP GF G +G GP GP G PG Sbjct: 112 TGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDP---GFPGGRGALGPGGPLGHPGE 168 Query: 357 PG--------IGQ-QGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGER 400 G +G +GI+G+RG G PG PG G G PG+PG GP G PG Sbjct: 169 KGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRP 228 Query: 401 GLPG------------------EGFPGP------------KGEKGSE---------GPTG 421 GL G +G PGP KGEKG + GP G Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288 Query: 422 PQGLQGLSIKGEKGDIGPVGPQ------GPMGIPG----IGSQGEQGIQGPIGP------ 465 +G G+ KGEKG G GP+ G G PG +G G+ G+ G IGP Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGN 348 Query: 466 ---PGPQG------------PAGQGLPGSKGEVGQMGPTGPRGPVG---------IGVQG 501 PGP G P G PG GE G +GP GP G +G IG G Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPG 408 Query: 502 PKGEPGSIGLPGQPGVPGE----DGAAGKKGEAGLPGARGPEGPPGK-------GQPGPK 550 P+G PG GLPG+ G+PG G GK G GLPGA G +G PG G PGP+ Sbjct: 409 PQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQ 468 Query: 551 GDEGK------KGSKGNQGQRGL----PGPEGPKGEPGI------MGPFGMPG----TSI 590 G +GK +G KG +G GL PGP GP G PG+ G G+PG Sbjct: 469 GIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGD 528 Query: 591 PGPPGPKGDRGGPGIPGFKGEPG----------LSIRGPKGVQGPRGPVGAPGL------ 634 PGPPG +G G PG G G PG ++G KG +GP GP G PG Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588 Query: 635 ------KGD---------------GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRG 673 KGD G+PG GP G GP GP GL G G +G PGV G Sbjct: 589 DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPG 648 Query: 674 PPGPSGPRGVGTQGPKGDTGQKGL--PGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGH- 729 PG GP G+ +G KGDT + PG GPPG+ G G KG GPQG PG G+ GH Sbjct: 649 HPGVRGPDGL--KGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHK 706 Query: 730 ---------GLPGQKGEHGERGDVGKKGDKGE--IGEPGSPGKQGLQGPKG 769 +PG G G+ GD G G+KG +G PG PG G+ G KG Sbjct: 707 GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKG 757 Score = 368 bits (945), Expect = e-101 Identities = 239/511 (46%), Positives = 281/511 (54%), Gaps = 86/511 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECG 301 +KG PG+PGPPG G PG ERG KG PG ++GE G GP G ++G+ GE+G+ G Sbjct: 970 QKGTPGEPGPPGDDGFPG---ERGDKGTPGMQGRRGEPGRYGPPGF--HRGEPGEKGQPG 1024 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---------QGNKGEP----GPP 348 PG G GS G G G G+ G G PG PGP GF +GNKG+P GPP Sbjct: 1025 PPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084 Query: 349 GPYGSPGAPGI-------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401 GP G PG+PG G+QG+ G +G G PG PGP G G PG G G+PG RG Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGP--PGSSGPPGCPGDHGMPGLRG 1142 Query: 402 LPGE-GFPGPKGEKGSEGPTGPQGLQGLS----------IKGEKGDIGP-----VGPQGP 445 PGE G PGP+G +G G GP G++G S +KG+KG G VGP GP Sbjct: 1143 QPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGP 1202 Query: 446 MGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI------ 497 +GIPG+ G +G+ G G I PPGP+G G G PGS G G G TG R P I Sbjct: 1203 VGIPGLKGERGDPGSPG-ISPPGPRGKKGPPGPPGSSGPPGPAGATG-RAPKDIPDPGPP 1260 Query: 498 GVQGPKGEPGSIGLPGQPGVPGE-DGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK 556 G QGP G G G PG PG+PG D G+ G+ GLPG GP GPPG PG KG G Sbjct: 1261 GDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGP--PGYKGFPGCD 1318 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-------TSIPGP---PGPKGDRGG-PGI 605 G G +G G PGP+GP G PG G G+PG T +PGP PGP D P I Sbjct: 1319 GKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRI 1378 Query: 606 PGFKGEPGLSIRGPKGVQG---PRGPVGAPGLKGDGYPGVPGPRGL---PGPPGPMGLRG 659 PG G PG+ RGP+G G RGP G PG KG+ PG+ G RG+ PG PGP G +G Sbjct: 1379 PGLPGAPGM--RGPEGAMGLPGMRGPSG-PGCKGE--PGLDGRRGVDGVPGSPGPPGRKG 1433 Query: 660 VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKG 690 DTG G PG GPPGP +G GPKG Sbjct: 1434 --DTGEDGYPGGPGPPGP-----IGDPGPKG 1457 Score = 319 bits (817), Expect = 1e-86 Identities = 218/539 (40%), Positives = 258/539 (47%), Gaps = 97/539 (17%) Query: 306 KGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIK 365 KG +G PGP GP+GP G G GP G G KG +G++G PG G G G G+ G Sbjct: 61 KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGV--PGFP 118 Query: 366 GERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG----FPGPKGEKGS---- 416 G G G PG PGP G G G G RG G PG RG G G PG KGEKG+ Sbjct: 119 GLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFI 178 Query: 417 -------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGP- 468 +G G GL GL G G GP GP G PG E G+ GP G PG Sbjct: 179 LGAVKGIQGDRGDPGLPGLP-----GSWGAGGPAGPTGYPG-----EPGLVGPPGQPGRP 228 Query: 469 --QGPAGQGLPGSKGEVGQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPG 516 +G G G+ G G+ G++G G GP + G +G KG PG +GLPG PG Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288 Query: 517 VPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 GE G G KGE G+PG GP G PG G PG G +G+ G G+ G GL GP+G G Sbjct: 289 RKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPG 347 Query: 576 EPGIMGPFGM---PGTSIPGPPGPKG---------DRGGPGIPGFKGEPGLSIRGPKGVQ 623 G GP G+ P + GPPG G D G PG PG G PG + G G Sbjct: 348 NRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPP 407 Query: 624 GPRGPVGAPGLKGD-----------GYPGVPGPRGLPGPPGPMGLRGVG----DTGAKGE 668 GP+G G PGL G+ G PG PG GLPG PG GL G G G Sbjct: 408 GPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGP 467 Query: 669 PGVRGPPGPSGPRGVGTQGPKGDTGQKGL----PGPPGPPGYGSQGIKGEQGPQGFPGPK 724 G++G GP G RG PKG+ G +GL PGP GPPG P G PG + Sbjct: 468 QGIKGKVGPPGGRG-----PKGEKGNEGLCACEPGPMGPPG-----------PPGLPGRQ 511 Query: 725 GTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLI 782 G+ G GLPG G G+ G G +G PG PGK G GP G+ G + ++ + Sbjct: 512 GSKGDLGLPGWLGTKGDPGPPGAEGP------PGLPGKHGASGPPGNKGAKGDMVVSRV 564 Score = 303 bits (775), Expect = 8e-82 Identities = 194/456 (42%), Positives = 226/456 (49%), Gaps = 82/456 (17%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK--GEAGERGPGGIPGYKGDKGERGECGK 302 GD G+PG PG G GI G RGPKGN G+ G G +G G PG G G GE G Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGL 1107 Query: 303 PGIKGDKGSPGPYGPKGP---------RGIQGITGPPG---DPGPKGFQGNKGEPGPPG- 349 PGI+G +GSPG GP G G+ G+ G PG DPGP+G QG+ G PGPPG Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGI 1167 Query: 350 --PYGSPGAPG------------------------IGQQGIKGERGQEGRPGAPGPIGVG 383 P GSPG G +G G+KGERG G PG P G Sbjct: 1168 KGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRG 1227 Query: 384 EPGQPGPRGPEGVPGERGLPGEG-----FPGPKGEKGSEGPTGPQGLQGLS--------I 430 + G PGP G G PG G G PGP G++G GP GP+G G + Sbjct: 1228 KKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLL 1287 Query: 431 KGEKGDI---GPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEV 483 +GE GD GP GP GP G PG G G+ G +GP+G PGPQGP G PG GE Sbjct: 1288 RGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGP--HGFPGPPGEK 1345 Query: 484 GQMGPTGPRGPVGIGVQGPKGEPGSIG----LPGQPGVPGEDGAAGKKGEAGLPGARGPE 539 G GP G +GP G+ GP+GEPG P PG+PG G G +G GLPG RGP Sbjct: 1346 GLPGPPGRKGPTGL--PGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPS 1403 Query: 540 GPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGD 599 GP KG+P G G +G G+PG GP G G G G PG PGPPGP GD Sbjct: 1404 GPGCKGEP---------GLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGG--PGPPGPIGD 1452 Query: 600 RGGPGI-PGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 G G PG+ G L + + Q P P+G P L Sbjct: 1453 PGPKGFGPGYLG-GFLLVLHSQTDQEPTCPLGMPRL 1487 Score = 234 bits (597), Expect = 3e-61 Identities = 158/377 (41%), Positives = 187/377 (49%), Gaps = 45/377 (11%) Query: 437 IGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPV 495 IGP G + + +G +G GP GP GP GP G P G GE G G GP G Sbjct: 44 IGPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAA 103 Query: 496 G-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPK 550 G G +GP G PG GL G PG PG G GK G +G G+RG G PG G GP Sbjct: 104 GDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPL 163 Query: 551 GDEGKKGSKGNQ-----GQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRG 601 G G+KG KGN +G+ G G G PG+ G +G G T PG PG G G Sbjct: 164 GHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPG 223 Query: 602 GPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPG------------LKGD-GYPGVPGPRGL 648 PG PG KG PG+ ++G G G G G+PG KG+ G G+PG GL Sbjct: 224 QPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGL 283 Query: 649 PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGPPGYG 707 PGPPG G G+ GAKGE G+ G PGP G P G+ G G G+ GL G PG +G Sbjct: 284 PGPPGRKGESGI---GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGL--FG 338 Query: 708 SQGIKGEQGPQGFPGPKGTM---------GHGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758 G KG+ G +G PGP G + G PG G +GE GDVG G G +G PG Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398 Query: 759 --PGKQGLQGPKGDLGL 773 G G GP+G GL Sbjct: 399 ACAGMIGPPGPQGFPGL 415 Score = 233 bits (593), Expect = 1e-60 Identities = 148/347 (42%), Positives = 171/347 (49%), Gaps = 55/347 (15%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERG 298 C + G PG G PG G+PG +G +G G PG KG +G G G+ G KG KG +G Sbjct: 1131 CPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKG 1190 Query: 299 ECGK-----------PGIKGDKGSPGPYG--PKGPRGIQGITGPPGDPGPKGFQGNKG-- 343 G PG+KG++G PG G P GPRG +G GPPG GP G G G Sbjct: 1191 ASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRA 1250 Query: 344 -----EPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV--------GEPGQPGP 390 +PGPPG G PG G RG G PG PG + + G PG PGP Sbjct: 1251 PKDIPDPGPPGDQGPPGP--------DGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGP 1302 Query: 391 RGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIP 449 GP G PG +G PG +G G KG G GP GP G G GEKG GP G +GP G+P Sbjct: 1303 PGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPG--PPGEKGLPGPPGRKGPTGLP 1360 Query: 450 GIGSQGEQGIQGPIGPPG-----PQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKG 504 G +G GPP P+ P G PG +G G MG G RGP G G +G G Sbjct: 1361 --------GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPG 1412 Query: 505 EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKG 551 G G+ G PG PG G G GE G PG GP GP G PGPKG Sbjct: 1413 LDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGP--IGDPGPKG 1457 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 434 bits (1115), Expect = e-121 Identities = 270/609 (44%), Positives = 314/609 (51%), Gaps = 91/609 (14%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGY---KGDKGERGEC 300 G+PG+ G G G PG++GE G +G G +KGEAG G G PG KGD+GE+GE Sbjct: 250 GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGEL 309 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGIT-------------------GPPGDPGPKGFQGN 341 G PG+KGD+G G GP GP G+ G T G PG PG G QG Sbjct: 310 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 369 Query: 342 KGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERG 401 GE GP GP G PGA GQ+G G G G PGAPG VG PG GP G G PG RG Sbjct: 370 PGELGPQGPTGPPGAK--GQEGAHGAPGAAGNPGAPG--HVGAPGPSGPPGSVGAPGLRG 425 Query: 402 LPGE----GFPGPKGEKGSEGPTGPQGLQGL---------------SIKGEKGDIGPVGP 442 PG+ G G GE+GS GP GP+G G ++G G GP+G Sbjct: 426 TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 485 Query: 443 QGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI 497 +G G PGI GS+G+ GI G GPPGP GP G +G PGS+G G GP GP G G+ Sbjct: 486 KGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGL 544 Query: 498 GVQGPKGE-------------PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK 544 G+ PG GLPG PG G+ G GK G G G +G GPP Sbjct: 545 SSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPP-- 602 Query: 545 GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPG 604 G PGP G G +GS+G +G G G +G +G PG+ G G PG PGPPG G G G Sbjct: 603 GLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGN--PGPPGADGIAGAAG 660 Query: 605 IPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGL 657 PG +G PG GP G QGP G G PG +G G PG PG G PG PGP G Sbjct: 661 PPGIQGSPGK--EGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA 718 Query: 658 RG----VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-YGS 708 RG G TG G PG RG G G G G G G TG +G GP GPPG GS Sbjct: 719 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 778 Query: 709 QGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGL 764 G GE GP G PG KG+ G GLPG G G G+ G+KG G+ G PG PG+ G Sbjct: 779 PGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 838 Query: 765 QGPKGDLGL 773 +G +GD G+ Sbjct: 839 KGERGDPGI 847 Score = 421 bits (1083), Expect = e-117 Identities = 262/595 (44%), Positives = 313/595 (52%), Gaps = 74/595 (12%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE---CGKP 303 PG+ GP G G+PG+ GE G +G PG E G +GP G PG KG +G G G P Sbjct: 346 PGEQGPKGEKGDPGLPGEPGLQGRPG-----ELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPG---DPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G G G+PGP GP G G G+ G PG + G KG G +G PGP GP G PGAPG+ Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460 Query: 360 --GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGV-----PGERGLPGE 405 +G GE G G PG PGP+G G PG PG RG G+ PG G PG+ Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 520 Query: 406 -GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVG-------PQGPMGIPGI-GSQGE 456 G PG +G G GP GP G GLS GDI + P GP G+PG+ G +G+ Sbjct: 521 KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580 Query: 457 QGIQGPIGPPGPQGPAGQ----GLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGS 508 +G+ G G G +G G+ GLPG G G G G RG G G QG G PG Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 509 IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQ 564 +G PG PG PG DG AG G G+ G+ G EGPPG G PG G+EGK+G G G Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 700 Query: 565 RGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGP 619 G PG G G PG G G PG T G PGP+G+ G G+PG +G PG GP Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 760 Query: 620 KGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPS 678 G QGP+GP G PG G G PG PGP G P G G+KGE G G PG Sbjct: 761 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTP-----------GQKGSKGENGSPGLPGFL 809 Query: 679 GPRG-VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPKGTMGH-GLP 732 GPRG G G KG G++G+PG PG PG+ G GIKG++GP PG KG G G+P Sbjct: 810 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGP---PGGKGQPGDPGIP 866 Query: 733 GQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICG 787 G KG G G G G+ G +G PG PG+ G G +G+ + E + +LI E G Sbjct: 867 GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE-SPSMETLRRLIQEELG 920 Score = 416 bits (1068), Expect = e-116 Identities = 261/625 (41%), Positives = 308/625 (49%), Gaps = 121/625 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G+ G PGP G G+PG G GP PG + GE G RG G+PG G KG+RG G PG Sbjct: 440 GEEGSPGPVGPRGDPGAPGLPGP---PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPG 496 Query: 305 IKGDKGS--------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG-----EPG----- 346 G +G PGP GP G +G G G PG PGP+G G G PG Sbjct: 497 SPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLL 556 Query: 347 --------PPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGV 396 PPGP G PG PG G +G+ G+ G+EG G G G G PG PG GP+G Sbjct: 557 AKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGS 616 Query: 397 PGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQGLS----IKGEKGDIGPVGP 442 GERG GE G PG G G+ GP G G+ G + I+G G GP GP Sbjct: 617 QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 676 Query: 443 QGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQ 500 QGP G+PGI G +G++G G GPPG G AG+ PG G G GP G +G G G Sbjct: 677 QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGE--PGLPGPEGARGPPGFKGHTGDSGAP 734 Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG----PPGKGQPGPKGDEGKK 556 GP+GE G++GLPGQ G+PG+DG G G G G RGP G P G+PGP G G+K Sbjct: 735 GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK 794 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEP 612 GSKG G GLPG GP+G PG G G+PG PG PG KG+RG PGI G KG P Sbjct: 795 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPP 854 Query: 613 G----------------LSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPG----------- 644 G + GP+G+ G GPVG PG G G+PG+ G Sbjct: 855 GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRL 914 Query: 645 ---------------------------PRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPG 676 +G PGPPGP G G+ G G GEPG G G Sbjct: 915 IQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGG 974 Query: 677 PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736 GP G GPKG+ G KG PG PG G++GE GP G PG G G+ G G Sbjct: 975 LEGPS--GPIGPKGERGAKGDPGAPG------VGLRGEMGPPGIPGQPGEPGYAKDGLPG 1026 Query: 737 EHGERGDVGKKGDKGEIGEPGSPGK 761 G +G+ G G G G PG PG+ Sbjct: 1027 IPGPQGETGPAGHPGLPGPPGPPGQ 1051 Score = 395 bits (1016), Expect = e-110 Identities = 258/614 (42%), Positives = 306/614 (49%), Gaps = 103/614 (16%) Query: 248 GDPGPPGTHGNPGIKGERGPKGNPG----NAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 G GP + K PG N + GE GE G G PG +G+ GE+G G+P Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI---- 359 G KG+ G PG G G RG +G G G+ G G +G++GE G GP G PG PG Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339 Query: 360 -------GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-------E 405 G+QG KGE+G G PG PG G PG+ GP+GP G PG +G G Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGL--QGRPGELGPQGPTGPPGAKGQEGAHGAPGAA 397 Query: 406 GFPGPKGEKGSEGPTGPQGLQGL----------------SIKGEKGDIGPVGPQGPMGIP 449 G PG G G+ GP+GP G G GE+G GPVGP+G G P Sbjct: 398 GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAP 457 Query: 450 GI------GSQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGE--VGQMGPTGPRGP 494 G+ G GE G++G G PGP G G G PGS+G+ +G GP GP GP Sbjct: 458 GLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP 517 Query: 495 VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGL--PGARG----------PEGPP 542 G KG PGS GL PG PG G AG+ G + L PG P GPP Sbjct: 518 -----PGDKGSPGSRGL---PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPP 569 Query: 543 G-KGQPGPKGDE---GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPK 597 G G PG KGD+ GK G +G +G++G GP G G PGI GP G G G G K Sbjct: 570 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 629 Query: 598 GDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGLPGPPG 653 GD+G PG+PGF G PG GP G G G G PG++G +G PG GP GLPG PG Sbjct: 630 GDQGHPGVPGFMGPPGNP--GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687 Query: 654 PMGLRG-------VGDTGAKGEPGVRGPPGPSGPRGV-------GTQGPKGDTGQKGLPG 699 G G G+ G GEPG+ GP G GP G G GP+G++G GLPG Sbjct: 688 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPG 747 Query: 700 PPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758 G PG G G G QGPQG GP G +G PG GE G G G+KG KGE G PG Sbjct: 748 QEGLPGKDGDTGPTGPQGPQGPRGPPGK--NGSPGSPGEPGPSGTPGQKGSKGENGSPGL 805 Query: 759 PGKQGLQGPKGDLG 772 PG G +GP G+ G Sbjct: 806 PGFLGPRGPPGEPG 819 Score = 372 bits (956), Expect = e-103 Identities = 234/530 (44%), Positives = 269/530 (50%), Gaps = 98/530 (18%) Query: 237 RKIC-ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGE---RGPGGIPGYKG 292 + +C +C G PG PG PG G+ G+ G+ G +G G +KGEAG GP GI G +G Sbjct: 558 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG--KKGEAGPPGLPGPPGIAGPQG 615 Query: 293 DKGERGECGKPGIKGDKGSP------GPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG 346 +GERG G+ G KGD+G P GP G GP G GI G G PG +G G +G PG Sbjct: 616 SQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPG 675 Query: 347 PPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPEGVPGERGL 402 P GP G PG P GE G+EGR G PGP G GEPG PGP G G PG +G Sbjct: 676 PQGPSGLPGIP--------GEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 727 Query: 403 PGE-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461 G+ G PGP+GE G+ G G +GL G+ GD GP GPQGP G G G+ G G Sbjct: 728 TGDSGAPGPRGESGAMGLPGQEGL-----PGKDGDTGPTGPQGPQG--PRGPPGKNGSPG 780 Query: 462 PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521 G PGP G GQ GSKGE G G G GP +GP GEPG G+PG+ GVPG+ Sbjct: 781 SPGEPGPSGTPGQ--KGSKGENGSPGLPGFLGP-----RGPPGEPGEKGVPGKEGVPGKP 833 Query: 522 GAAGKKGEAGLPGARGPEGPP-GKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM 580 G G KGE G PG +G +GPP GKGQPG G G KG G G +GLPG GP G PG Sbjct: 834 GEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPP 893 Query: 581 GPFGMPG------------------------------------------TSIPGPPGPKG 598 G G PG PGPPGP G Sbjct: 894 GQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPG 953 Query: 599 DRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGP--RGLPGPPGPM 655 G PG G GEPG G G++GP GP+G G +G G PG PG RG GPPG Sbjct: 954 KDGLPGRAGPMGEPGRP--GQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIP 1011 Query: 656 GLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG 705 G G G PG+ GP G +GP G GLPGPPGPPG Sbjct: 1012 GQPGEPGYAKDGLPGIPGPQGETGP-----------AGHPGLPGPPGPPG 1050 Score = 344 bits (882), Expect = 3e-94 Identities = 230/578 (39%), Positives = 277/578 (47%), Gaps = 90/578 (15%) Query: 266 GPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDK-----GSPGPYGPKG 319 GP+ +P N +G G G G +C P G + G+ GP + Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAP--QCSMPKGTGHEFSAALGTQGPADQRA 229 Query: 320 PRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPG 378 I PG K G GE G G G PG G IG+QG+ G G++G G PG Sbjct: 230 DARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPG 289 Query: 379 PIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSI-----KGE 433 G PG G +G +G GE GLPG G +GEKG GP GP GL G + Sbjct: 290 APGF--PGVRGEKGDQGEKGELGLPG--LKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRM 345 Query: 434 KGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTG--- 490 G+ GP G +G G+PG E G+QG G GPQGP G PG+KG+ G G G Sbjct: 346 PGEQGPKGEKGDPGLPG-----EPGLQGRPGELGPQGPTGP--PGAKGQEGAHGAPGAAG 398 Query: 491 -PRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----G 545 P P +G GP G PGS+G PG G PG+DG G+KG AG G+ GP GP G G Sbjct: 399 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458 Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGE------PGIMGPFGMPGTSIPGPPGP--- 596 PGP G +GK G G +G GLPGP G KG+ PG G G PG + GPPGP Sbjct: 459 LPGPPG-KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGP 517 Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQG---------------------PRGPVGAPGLK 635 GD+G PG G G PG +GP G G P GP G PGL Sbjct: 518 PGDKGSPGSRGLPGFPG--PQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL- 574 Query: 636 GDGYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKG 690 PG G +G+PG PG G G G G G PG+ GP G G RG G G KG Sbjct: 575 ----PGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG 630 Query: 691 DTGQKGLPGPPGPPG-------------YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKG 736 D G G+PG GPPG G GI+G G +G PGP+G G G+PG++G Sbjct: 631 DQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEG 690 Query: 737 EHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLT 774 + G G G G+ G+ GEPG PG +G +GP G G T Sbjct: 691 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 728 Score = 266 bits (680), Expect = 8e-71 Identities = 179/451 (39%), Positives = 213/451 (47%), Gaps = 95/451 (21%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG+PGPPG G G G G +G+PG ++G G +GP G+PG G++G+ G GKPG Sbjct: 642 GPPGNPGPPGADGIAGAAGPPGIQGSPG--KEGPPGPQGPSGLPGIPGEEGKEGRDGKPG 699 Query: 305 IKGDKGS------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 G+ G PGP G +GP G +G TG G PGP+G G G PG G G G G Sbjct: 700 PPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTG 759 Query: 359 -IGQQGIKGERGQEGR------PGAPGPIGV----------GEPGQPG---PRGPEGVPG 398 G QG +G RG G+ PG PGP G G PG PG PRGP G PG Sbjct: 760 PTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819 Query: 399 ERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG----IGS 453 E+G+PG EG PG GE G +G G G IKG+KG G G G GIPG G Sbjct: 820 EKGVPGKEGVPGKPGEPGFKGERGDPG-----IKGDKGPPGGKGQPGDPGIPGHKGHTGL 874 Query: 454 QGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEV----------------------------- 483 G QG+ G GP GP GP GQ G PG +GE Sbjct: 875 MGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQM 934 Query: 484 ---------GQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLP 533 G+ GP GP G G+ G GP GEPG PGQ G+ G G G KGE G Sbjct: 935 PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAK 991 Query: 534 GARGPEGPPGKGQPGPKGDEGKKGSKG--NQGQRGLPGPEG---PKGEPGIMGPFGMPGT 588 G G G +G+ GP G G+ G G G G+PGP+G P G PG+ GP Sbjct: 992 GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGP------ 1045 Query: 589 SIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 PGPPG PG +++GP Sbjct: 1046 --PGPPGQCDPSQCAYFASLAARPG-NVKGP 1073 Score = 253 bits (647), Expect = 5e-67 Identities = 161/381 (42%), Positives = 182/381 (47%), Gaps = 66/381 (17%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 E G PG PG PG G PG+ G G +G PG KG G+ G G G G G G+ Sbjct: 692 EGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG--FKGHTGDSGAPGPRGESGAMGLPGQE 749 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G PG GD G GP GP+GPRG G G PG PG G G G+ G G GSPG PG Sbjct: 750 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 809 Query: 360 ------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKG 412 G+ G KG G+EG PG PG G GE G PG +G +G PG +G PG+ PG G Sbjct: 810 GPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGD--PGIPG 867 Query: 413 EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG------------------IGSQ 454 KG G GPQGL GE G +GP GP G G PG +G Q Sbjct: 868 HKGHTGLMGPQGL-----PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQ 922 Query: 455 GE------------------QGIQGPIGPPGPQGPAGQGLP-GSKGEVGQMGPTGPRGPV 495 E QG GP GPPG G G+ P G G GQ G GP GP+ Sbjct: 923 LETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPI 982 Query: 496 GIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGK 555 GPKGE G+ G PG PGV G +GE G PG G G PG + G G G Sbjct: 983 -----GPKGERGAKGDPGAPGV-------GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGP 1030 Query: 556 KGSKGNQGQRGLPGPEGPKGE 576 +G G G GLPGP GP G+ Sbjct: 1031 QGETGPAGHPGLPGPPGPPGQ 1051 Score = 107 bits (266), Expect = 8e-23 Identities = 88/241 (36%), Positives = 109/241 (45%), Gaps = 35/241 (14%) Query: 548 GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPG 607 GP+ D + +G QG G +G ++ P + P PKG G Sbjct: 172 GPRTDPWENVDQGAQGACG-------RGNTSVL-----PSSVAPQCSMPKGT-------G 212 Query: 608 FKGEPGLSIRGPKGVQGPR------GPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-V 660 + L +GP + APGLK G PG RG G PG GLRG + Sbjct: 213 HEFSAALGTQGPADQRADARASCILAAKTAPGLKQ--LNGEPGERGEDGLPGKPGLRGEI 270 Query: 661 GDTGAKGEPGVRGPPG-PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQG 719 G+ G G PG +G G P P G +G KGD G+KG G PG G +G KGE GP G Sbjct: 271 GEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKG--DRGEKGEAGPAG 328 Query: 720 FPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPG---SPGKQGLQGPKGDLGLTKE 776 PG GT P + GE+G G+KGD G GEPG PG+ G QGP G G + Sbjct: 329 PPGLPGTTSLFTPHPRMP-GEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQ 387 Query: 777 E 777 E Sbjct: 388 E 388 Score = 66.6 bits (161), Expect = 1e-10 Identities = 40/104 (38%), Positives = 45/104 (43%), Gaps = 14/104 (13%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK----------- 291 E G PG G G G G KGERG KG+PG G GE GP GIPG Sbjct: 966 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLP 1025 Query: 292 ---GDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGD 332 G +GE G G PG+ G G PG P + PG+ Sbjct: 1026 GIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPGN 1069 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 433 bits (1114), Expect = e-121 Identities = 290/652 (44%), Positives = 341/652 (52%), Gaps = 135/652 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPG-NAQKGEAGERGPGGIPG------------YK 291 GD GD GP G G+PG+ G GP G PG G G GP GIPG K Sbjct: 654 GDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIK 713 Query: 292 GDKGERG---ECGKPGIKGDKGSPGPYGPKGPR------------GIQGITGPP------ 330 GDKGE+G E G+PG GDKG+ G GP G R G+QG +GPP Sbjct: 714 GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFP 773 Query: 331 ---------GDPGPKGFQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAP 377 G GPKG GN+G PGPPG G+ G G G+ G +G+ GQ+G G P Sbjct: 774 GDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEP 833 Query: 378 GPIGV-GEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKG 432 GP G+ GE G G G G G GLPGE G G KGE+GS GP GPQG +G + G Sbjct: 834 GPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKG--VMG 891 Query: 433 EKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGPAG----QGLPGSKGEVGQMG 487 G G GP GP+G+PG +G++G G QGP G G +GP G QG+ G+KGE G G Sbjct: 892 YPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQG 951 Query: 488 PTGPRGPVG----IGVQGPKGEPGSIGLPGQP---GVPGEDGAAGKKGEAGLPGARGPEG 540 GP G +G G +G +G+PG GLPG G+PGE G G +G+ G PG G EG Sbjct: 952 KRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEG 1011 Query: 541 PPG-------KGQPGPKGD---------------------------EGKKGSKGNQGQRG 566 PPG +G+PG KGD +GK G KG G RG Sbjct: 1012 PPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGGRG 1071 Query: 567 LPGPEGPKGE---PGIMGPFGMPG-TSIPGP------------PGPKGDRG--GP-GIPG 607 LPG +G KGE PGI+GP G G T +PGP PG KGD+G GP G G Sbjct: 1072 LPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVG 1131 Query: 608 FKGEPG-LSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665 +G PG + GPKG +G RG VG GL G DG PG+PG RG G PGP GL G G Sbjct: 1132 SRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGL--PGPKGE 1189 Query: 666 KGEPG----VRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGF 720 KG PG V GPPGP G P VG QG +G+ G +G G G PG +G G+QGP G Sbjct: 1190 KGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL--RGATGQQGPPGE 1247 Query: 721 PGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PG +G G KGE G G+ GKKG G G+PG PG QGL GPKG G Sbjct: 1248 PGDQGEQ-----GLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQG 1294 Score = 424 bits (1091), Expect = e-118 Identities = 270/641 (42%), Positives = 330/641 (51%), Gaps = 113/641 (17%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-------QKGEAGERGPGGIPGYKGDKG 295 ++G G PGP G G PG+ G +GPKG+PG + +KG+ G G G PG +GDKG Sbjct: 511 KRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPGQPVPGEKGDQGLSGLMGPPGMQGDKG 570 Query: 296 ERGECGKPGIKGDKGSPG---PYGPKGPRGIQGITGPPGDPGPKGFQG---NKGEPGPPG 349 +G G PG+ G++G PG G G G QG+ GP G+PGPKG QG + GE G G Sbjct: 571 LKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLG 630 Query: 350 PYGSPGAPGI-GQQGIK---------GERGQEGRPGAPGPI-GVGEPGQP---------G 389 P G G PGI G++G K G+RG G G+PG + G G PG P G Sbjct: 631 PEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG 690 Query: 390 PRGPEGVPGERGLPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGI 448 P GP G+PG GL G +G PG KG+KG +G G G G G+KG +G GP G G Sbjct: 691 PIGPAGIPGPMGLSGNKGLPGIKGDKGEQGTAGELGEPG--YPGDKGAVGLPGPPGMRGK 748 Query: 449 PG-IGSQGEQGIQGPIGPPGPQG-PAGQGLPGS------KGEVGQMGPTGP--------- 491 G G G+ G+QGP GPPGP+G P G+PG KG +G GP GP Sbjct: 749 SGPSGQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGE 808 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQ 546 GP+G G GP+G+PG G G+PG G G G +G G G GP G PG+ G Sbjct: 809 EGPIGAFGELGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868 Query: 547 PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG----TSIPGPPGPKGDRGG 602 G KG+ G G G QG++G+ G GP G PG +GP G+PG PG GPKG RG Sbjct: 869 IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928 Query: 603 PGIPGFKGEPGL-SIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLPGP------ 651 G G GE G+ +G KG QG RGP G G G+ G+ G PG +GLPG Sbjct: 929 RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988 Query: 652 PGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG----------VGTQGPKGDTGQKGLPGP 700 PG GLRG+ GD G GE G+ GPPG G G VGT G G TG+ GL G Sbjct: 989 PGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGE 1048 Query: 701 PGPPG----YGSQGIKGEQGPQGFPGPKGTMGH-------------------------GL 731 PG PG G G+KG G +G PG G G G+ Sbjct: 1049 PGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGI 1108 Query: 732 PGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PGQ+G G++GD G+ G GE+G G PGK G GPKG G Sbjct: 1109 PGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARG 1149 Score = 417 bits (1073), Expect = e-116 Identities = 273/633 (43%), Positives = 331/633 (52%), Gaps = 107/633 (16%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGER---------GPKGNPGNAQKGEAGERGPGGIPGYK 291 E KG G+ GPPG G G +GE GP+G PG QKG AGE GP G+ G Sbjct: 785 EGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG--QKGYAGEPGPEGLKGEV 842 Query: 292 GDKGERGECGKP---------------GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP- 335 GD+G G+ G+ G KG++GSPGP GP+G +G+ G GPPG PGP Sbjct: 843 GDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPI 902 Query: 336 -----KGFQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-VGEP 385 G G +G PG GP G G+ G +G+QGI+G +G++G G GP G +G+ Sbjct: 903 GPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKT 962 Query: 386 GQPGPRGPEGVP---------GERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLS 429 G PG RG +G P G+RGLPGE G GP GE G EGP G +G GL Sbjct: 963 GNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQ 1022 Query: 430 IK-GEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484 + G KGD+G G G G PG+ G+ GE+G+QG G G P G+GLPG GE G Sbjct: 1023 GEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV--PGGRGLPGEDGEKG 1080 Query: 485 QMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG 543 +MG G GP+G G G G G +G+PGQ G PG+ G G+ G G G+RGP G G Sbjct: 1081 EMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIG 1140 Query: 544 KGQP----------------GPKGDEGKKGSKGNQGQ---RGLPGPEGPKGEPG----IM 580 K P GP G+ G G +G+QGQ GLPGP+G KG PG ++ Sbjct: 1141 KSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVL 1200 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQGP---RGPVGAPGLKG 636 GP G G PGP G +G+RG PG G+KG G+ +RG G QGP G G GLKG Sbjct: 1201 GPPGPRGE--PGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKG 1258 Query: 637 D-------GYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG-VGTQG 687 + G G PGP G PG PG GL G G G G G+ G PG GP G G G Sbjct: 1259 ERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPG 1318 Query: 688 PKGDTGQKGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHG 739 +G G+ GL G PGPPG GS GI+G +G QG PG G G G G +G+ G Sbjct: 1319 IRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQG 1378 Query: 740 ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 GD G KG GE G G G QG GPKG G Sbjct: 1379 PCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEG 1411 Score = 404 bits (1037), Expect = e-112 Identities = 272/651 (41%), Positives = 338/651 (51%), Gaps = 101/651 (15%) Query: 245 GDPGDPGPPGTHGNPGIKG------ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 G+ G PGPPG G G +G E GP+G PG QKG AGE GP G+ G GD+G G Sbjct: 792 GNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPG--QKGYAGEPGPEGLKGEVGDQGNIG 849 Query: 299 ECGKPGI---------------KGDKGSPGPYGPKGPRGIQGITGPPGDPGP------KG 337 + G+ G KG++GSPGP GP+G +G+ G GPPG PGP G Sbjct: 850 KIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPG 909 Query: 338 FQGNKGEPGPPGPYGSPGAPG----IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRG 392 G +G PG GP G G+ G +G+QGI+G +G++G G GP G +G+ G PG RG Sbjct: 910 HVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERG 969 Query: 393 PEGVPG---------ERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLSIK-GEKG 435 +G PG +RGLPGE G GP GE G EGP G +G GL + G KG Sbjct: 970 FQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAKG 1029 Query: 436 DIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGP 491 D+G G G G PG+ G+ GE+G+QG G G P G+GLPG GE G+MG G Sbjct: 1030 DVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV--PGGRGLPGEDGEKGEMGLPGI 1087 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPK 550 GP+G G G G G +G+PGQ G PG+ G G+ G G G+RGP G GK GPK Sbjct: 1088 IGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKS--GPK 1145 Query: 551 GDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI----- 605 G +G++G G GL GP+G G PG G G PG S G PGPKG++G PG Sbjct: 1146 G---ARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPS--GLPGPKGEKGYPGEDSTVL 1200 Query: 606 --PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV-- 660 PG +GEPG P G QG RG GA G KG G PG+ G G GPPG G +G Sbjct: 1201 GPPGPRGEPG-----PVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQG 1255 Query: 661 --GDTGAKGEPGVRGPPGPSGPRGV----------GTQGPKGDTGQKGLPGPPGPPGY-- 706 G+ G++G G +G PGPSG G+ G QG G G G PG GPPG Sbjct: 1256 LKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQG 1315 Query: 707 --GSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPG 760 G +G G G G PGP G G G PG +G GE+G G+ G +G+ G G+ G Sbjct: 1316 LPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQG 1375 Query: 761 KQGLQGPKGDLGLTKEEIIKLITEICGC-GPKCKETPLELVFVIDSSESVG 810 QG G G G E ++ +T G GPK E +V + +G Sbjct: 1376 DQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIG 1426 Score = 399 bits (1024), Expect = e-110 Identities = 262/590 (44%), Positives = 307/590 (52%), Gaps = 92/590 (15%) Query: 265 RGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPR--- 321 RGPKG+ G G GP GIPG G +G RG PG G+ G PG GPKGP+ Sbjct: 488 RGPKGDTG-----PPGPPGPAGIPGPSGKRGPRGI---PGPHGNPGLPGLPGPKGPKGDP 539 Query: 322 ---------------GIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-IGQQGIK 365 G+ G+ GPPG G KG +G+ G PG PG G PG G IG G Sbjct: 540 GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599 Query: 366 GERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEK 414 G +G G G PGP G GE GQ GP G G+PG RG G +GFPG G++ Sbjct: 600 GRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659 Query: 415 GSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQ 469 G G G GL G G +G +GPVGP GP GIPG +G G +G+ G G G Q Sbjct: 660 GPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDKGEQ 719 Query: 470 GPAGQ----GLPGSKGEVGQMGPTGPRGPVG-------IGVQGPKGEPGSIGLPGQPGVP 518 G AG+ G PG KG VG GP G RG G G+QGP G PG G PG G+P Sbjct: 720 GTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDIGIP 779 Query: 519 GEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQRGL---PGPE 571 G++G G K GL G RGP GPPG +G+ GP G G+ G +G GQ+G PGPE Sbjct: 780 GQNGPEGPK---GLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPE 836 Query: 572 GPKGEPGIM---------GPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPK 620 G KGE G GP G+PG + G G KG+RG PG G +GE G + GP Sbjct: 837 GLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGYPGPP 896 Query: 621 GVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPS 678 GV GP GP+G PG G G PG GP+G G GP GL G G GAKGE G +G GP Sbjct: 897 GVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPH 956 Query: 679 GPRG-------------VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPK 724 G G G QG G TG +GLPG PG G G G GE G +G PG + Sbjct: 957 GLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTE 1016 Query: 725 GTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G G G PG KG+ G G VG G+ G GEPG+PG++GLQG G G+ Sbjct: 1017 GESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGV 1066 Score = 398 bits (1023), Expect = e-110 Identities = 247/593 (41%), Positives = 313/593 (52%), Gaps = 81/593 (13%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN-------AQKGEAGERGPGGIPGYKGDKGER 297 G G GPPG+ G G +G RGP G G +KG+ G+RGP G+ G G+ GER Sbjct: 909 GHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGER 968 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 G GKPG++G GS G G G G++G+ G G PG G +G G G G G PGA Sbjct: 969 GFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPGEMGMEGPPGTEGESGLQGEPGAK 1028 Query: 358 G----IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE-------- 405 G G G GE G G PGAP GE G G G +GVPG RGLPGE Sbjct: 1029 GDVGTAGSVGGTGEPGLRGEPGAP-----GEEGLQGKDGLKGVPGGRGLPGEDGEKGEMG 1083 Query: 406 --GFPGPKGEKGSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPG----IG 452 G GP G G G GP+G+ G+ KG+KG IGP G G G PG G Sbjct: 1084 LPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG 1143 Query: 453 SQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-----------IGVQ 500 +G +G +G +G G GP G+ G+PG +G GQ GP+G GP G +G Sbjct: 1144 PKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPP 1203 Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK 559 GP+GEPG +G G+ G PG +G G G GL GA G +GPPG+ G G +G +G++GS+ Sbjct: 1204 GPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSE 1263 Query: 560 GNQGQRGLPGPEGPKGEP---GIMGPFGMPG----TSIPGPPGPKGDRGGPGIPGFKGEP 612 GN+G++G PGP G G P G++GP G+ G I G PG G G G+PG +G P Sbjct: 1264 GNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGP 1323 Query: 613 GLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPR---GLPGPPGPMGLRG----VGDTGA 665 G + G G GP G G+ GL G PG+ GP+ GLPG PG G RG GD G Sbjct: 1324 GRT--GLAGAPGPPGVKGSSGLPGS--PGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGP 1379 Query: 666 KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPK 724 G+PG++G PG G +G+ TG +G PGP GP G G GI G +GP G G Sbjct: 1380 CGDPGLKGQPGEYGVQGL--------TGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNT 1431 Query: 725 GTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G +G G G+ G GE+G G+ G +G G+PG PG G GP+ + + Sbjct: 1432 GPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDI 1484 Score = 372 bits (956), Expect = e-103 Identities = 238/523 (45%), Positives = 279/523 (53%), Gaps = 69/523 (13%) Query: 305 IKGDKGSPGPYGPKGPRGIQGIT---GPPGDPGPKGFQGNKGEPGPPGPYGSPG-APGIG 360 ++G KG GP GP GP GI G + GP G PGP G G G PGP GP G PG +PG Sbjct: 487 LRGPKGDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSPG-- 544 Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------EGFPGPKG 412 Q + GE+G +G G GP G+ G+ G G G G+PGE+G+PG G+PG +G Sbjct: 545 -QPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQG 603 Query: 413 EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPGP 468 G EG GP+G QG G G+ G +GP+G GIPGI G +G QG G G GP Sbjct: 604 LAGPEGNPGPKGAQGFI--GSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGP 661 Query: 469 QG-------PAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGED 521 G G G PG G G +GP GP GP GI GP G G+ GLPG G GE Sbjct: 662 AGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGI--PGPMGLSGNKGLPGIKGDKGEQ 719 Query: 522 GAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMG 581 G AG+ GE G PG +G G PGP G GK G G G GL GP GP G G G Sbjct: 720 GTAGELGEPGYPGDKG-----AVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPG 774 Query: 582 PFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP 640 G+PG + P GP G G+RG PG PG KG G GP G G GP G PG K GY Sbjct: 775 DIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQG--EEGPIGAFGELGPRGKPGQK--GYA 830 Query: 641 GVPGPRGLP------------GPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQG 687 G PGP GL G GP+GL G VG TG+ GE G RG PGP GP+ G +G Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQ--GEKG 888 Query: 688 PKGDTGQKGLPGPPGP---PGY-GSQGIKGEQGPQGFPGPKGTMG-------HGLPGQKG 736 G G G+PGP GP PG+ G++G G QGP+G G +G G G G+KG Sbjct: 889 VMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKG 948 Query: 737 EHGERGD---VGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 + G+RG +GK G+ GE G G PG QGL G GD GL E Sbjct: 949 DQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGE 991 Score = 309 bits (791), Expect = 1e-83 Identities = 209/491 (42%), Positives = 259/491 (52%), Gaps = 79/491 (16%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGECGKP 303 G+ G GPPGT G G++GE G KG+ G A G GE G G PG G++G +G+ G Sbjct: 1005 GEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLK 1064 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGD------PGPKGF------------QGNKGEP 345 G+ G +G PG G KG G+ GI GP G PGP+G +G+KG+ Sbjct: 1065 GVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQI 1124 Query: 346 GPPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLP 403 GP G GS G PG IG+ G KG RG G G G +G GEPG PG RG +G PG GLP Sbjct: 1125 GPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQGQPGPSGLP 1184 Query: 404 GEGFPGPKGEKGSEG-------PTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQG 455 G PKGEKG G P GP+G G + +GE+G+ G G +G +G+PG+ +G Sbjct: 1185 G-----PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGL--RG 1237 Query: 456 EQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI----GVQGPKG------ 504 G QGP G PG QG G +G GS+G G+ G GP G GI G+ GPKG Sbjct: 1238 ATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHG 1297 Query: 505 ------EPGSIGLPGQPGVPGEDGAAGK------------KGEAGLPGARGPEGPPGK-- 544 PG IG PG+ G+PG G G+ KG +GLPG+ G +GP G+ Sbjct: 1298 ADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQG 1357 Query: 545 --GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGG 602 GQPG +G G +G++G+QG G PG +G GE G+ G G G PGP GP+GD G Sbjct: 1358 LPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQG--FPGPKGPEGDAGI 1415 Query: 603 PGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLP---GPPGP 654 GI G KG G GP G +G GP G G +G+ G G GPRG P GPPG Sbjct: 1416 VGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGA 1475 Query: 655 MGLRGVGDTGA 665 G R D A Sbjct: 1476 PGPRKQMDINA 1486 Score = 227 bits (578), Expect = 5e-59 Identities = 150/362 (41%), Positives = 182/362 (50%), Gaps = 73/362 (20%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G+ G GPPG G G KG RG +G G+ G G G GIPGY+G +G+ G G PG Sbjct: 1128 GEVGSRGPPGKIGKSGPKGARGTRGAVGHL--GLMGPDGEPGIPGYRGHQGQPGPSGLPG 1185 Query: 305 IKGDKGSPG-------PYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 KG+KG PG P GP+G G G G G+PG +G++G+ G PG G G G P Sbjct: 1186 PKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPP 1245 Query: 358 GI----GQQGIKGERGQEG---RPGAPGPIGV-------------------------GEP 385 G G+QG+KGERG EG + GAPGP G G P Sbjct: 1246 GEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNP 1305 Query: 386 GQPGPRGPEGVPGERGLPGE----GFPGPKGEKGS---------EGPTGPQGLQGL-SIK 431 G+ GP G +G+PG RG PG G PGP G KGS +GP G QGL G I+ Sbjct: 1306 GKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQ 1365 Query: 432 GEKGDIGPVGPQGPMGIPGI-------GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEV 483 G++G G G QGP G PG+ G QG G QG GP GP+G AG G+ G KG + Sbjct: 1366 GKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPI 1425 Query: 484 GQMGPTGPRGPVGI----------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLP 533 G G TGP G GI G +G +GE G G GQPG PG GA G + + + Sbjct: 1426 GHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPGPRKQMDIN 1485 Query: 534 GA 535 A Sbjct: 1486 AA 1487 Score = 222 bits (565), Expect = 2e-57 Identities = 133/296 (44%), Positives = 164/296 (55%), Gaps = 29/296 (9%) Query: 243 EKGDPGDP----GPPGTHGNPGIKGERGPKGNPGN----------AQKGEAGERGPGGIP 288 EKG PG+ GPPG G PG G++G +G PG +G G++GP G P Sbjct: 1189 EKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEP 1248 Query: 289 GYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G +G++G +GE G G KG KG+PGP G G G+QG+ GP G G G G G PG Sbjct: 1249 GDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGADGISGNPGKI 1308 Query: 349 GPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGE-G 406 GP G G P GI+G G+ G GAPGP GV G G PG G +G GE+GLPG+ G Sbjct: 1309 GPPGKQGLP-----GIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPG 1363 Query: 407 FPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGP 465 G +G +G++G GP G GL KG+ G+ G G G G PG G +G+ GI G GP Sbjct: 1364 IQGKRGHRGAQGDQGPCGDPGL--KGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGP 1421 Query: 466 PGPQGPAGQGLP-GSKGEVGQMGPTGPRGPVGI----GVQGPKGEPGSIGLPGQPG 516 GP G G P G +G +G G TGPRG G G QGP+G+PG G PG PG Sbjct: 1422 KGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRGQPGPPGPPGAPG 1477 Score = 166 bits (421), Expect = 9e-41 Identities = 108/248 (43%), Positives = 128/248 (51%), Gaps = 30/248 (12%) Query: 241 ECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGEC 300 E KG G PGP G G PG++G GP KG G G GI G G G G+ Sbjct: 1263 EGNKGKKGAPGPSGKPGIPGLQGLLGP--------KGIQGYHGADGISGNPGKIGPPGKQ 1314 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI- 359 G PGI+G G G G GP G++G +G PG PG +G +G +G PG PG G G G Sbjct: 1315 GLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQ 1374 Query: 360 GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEG 418 G QG G+ G +G+PG G G+ G G PGP+GPEG G G+ GPKG G G Sbjct: 1375 GDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI-----SGPKGPIGHRG 1429 Query: 419 PTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPG 478 TGP G +G+ IGP G GP G G +GE G QGP G PGP GP PG Sbjct: 1430 NTGPLGREGI--------IGPTGRTGPRGEKGF--RGETGPQGPRGQPGPPGP-----PG 1474 Query: 479 SKGEVGQM 486 + G QM Sbjct: 1475 APGPRKQM 1482 Score = 79.3 bits (194), Expect = 2e-14 Identities = 46/112 (41%), Positives = 61/112 (54%), Gaps = 15/112 (13%) Query: 666 KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725 +G G GPPGP GP G+ GP G G +G+PGP G PG G+ G +GP+G PG Sbjct: 488 RGPKGDTGPPGPPGPAGI--PGPSGKRGPRGIPGPHGNPGL--PGLPGPKGPKGDPG--F 541 Query: 726 TMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 + G +PG+KG+ G G +G PG G +GL+G G GL E+ Sbjct: 542 SPGQPVPGEKGDQGL---------SGLMGPPGMQGDKGLKGHPGLPGLPGEQ 584 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 431 bits (1109), Expect = e-120 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%) Query: 244 KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295 +GDPG PGPPG G PG I+G RG +G PG Q+G G+ GP G PG G G Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 GE G PGI G +G GP G +G G GI GPPG+ G G G G GPPGP G+PG Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 356 APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389 PG G GI G +GQ G PGA PGP + G PG+ G Sbjct: 911 TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Query: 390 PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435 RG G+PG +GL G G PGP+G+ GS G G GL+G+ KG++G Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030 Query: 436 DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 +G G G G+PGI G QG++G G PGP GP G GLPG G+ G+MG GP Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543 G +G G +G G PGS GLPG+PG G+ G G KG G PG RGP G PG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 544 ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569 KG+ PGP+G+ G +G+KG++G G PG Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210 Query: 570 ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620 P GP G G GP G+PG IPG G P G RG PG PG G PG + I+G K Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 621 GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675 G G GP G PG GD P G PG GLPGP G G +G G G KG PG G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 676 GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728 GP GP +G +GP G G G LPG PGPPG G G++GE GP G PG G G Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Query: 729 -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G PG+ G+ G G G+KG+KG GEPG G GL G KG G Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 422 bits (1084), Expect = e-117 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 EKGD G PGPPG G G +G GP G PG+ G RG G PG KG KGERG GK Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 303 --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344 PG+ G G PGP G KGP G G+ G G PG G G KGE Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471 Query: 345 PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391 PG PGP G PG PG+ G +GI G +G +G PG+PG G+ G PG PG + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 392 GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433 G G+ GE+G +PG+ G PG KG G G G +GL G L++ GE Sbjct: 532 GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591 Query: 434 KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484 KGD GP G P GP G PG G QGE G+QG G PG GP G+ G +GE+ Sbjct: 592 KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649 Query: 485 QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528 GP GP GP G G QGP G PGS+G G PG+PG D G G KG Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 529 EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579 + G PG +G G PGK G+PG G G G+K G G G PG G GE G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 580 MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623 +G G+PG +PG P GP+GD G PG PG +G PG I GP+G Q Sbjct: 770 IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827 Query: 624 --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675 GP+G G PGL G+PG G G+PG G MG +G G G PG+ GPP Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885 Query: 676 GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724 G G P +G GP G+ G G G PG PG G+ G KGEQG +G PGP Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944 Query: 725 GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774 + H + G KGE G +G G G+KG G PG PG +GL+ GP+GDLG T Sbjct: 945 SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Score = 411 bits (1057), Expect = e-114 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293 C + G+PG PG PG PG KGE G G PG ++G +GE G G+PG G Sbjct: 722 CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G G G +GD G PGP G +GP G I+G G G PG G +G +G G GP Sbjct: 779 PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404 G PG PG+ + G GE G G PG G +G G PG GP G +GV G G PG Sbjct: 839 GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456 G PGP G G+ G G G+ G +KG++G G G QG G PG IG +GE Sbjct: 899 AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956 Query: 457 QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514 G++G G PG +G G G+PG KG G GP GP GP G +G G GEPG G+PG Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 515 PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556 G G G+ GK+G G PG G G PG G PGP GD G Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600 G G +G+ G PGP G G G G G PG+ +PG PGP GD R Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 601 GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648 G PG+PGF G PG + IRG +G G GP G PG +G+ G G G RG Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701 PG PG G +G +GD G +G G+ G PGP G P G +GP G G G PGPP Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 702 GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751 GPPG GIKG++G G PGPKG G G PG G G RGD G +G G Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316 Query: 752 EIGEPGSPGKQGLQGPKGDLG 772 GE G+PG G GP G +G Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337 Score = 408 bits (1048), Expect = e-113 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298 ++G PG PG G G PG KGE+G KGNPG ++ G+ GE G G G G+KG RG Sbjct: 914 QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347 G PG+KG KG PGP GP GPRG G TG PG+PG +G GN G PG Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033 Query: 348 -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403 PG G PG PGI G QG KGE G EG RPG PGP G+PG PG G +G G+ G P Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091 Query: 404 G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451 G EG PG G G G GP G L KG KG +GP G +GP G+PG Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 452 -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486 G QG GI GP G PPGP+G G G PG G G M Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 487 GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545 G GPRGP GI G GP G PG+I +PG+ G G G G PGA GP GPPG Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262 Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605 G KGD KGS G+ G +G PG G G PG +G G PG +PGP G G +G PG+ Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317 Query: 606 PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665 G KG PG G G GP GP G PG++GD PG LPG PGP G Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365 Query: 666 KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724 GEPG++G PGP GP G +G GP+G G+ G PG PGP G KG +G +G PGP Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420 Query: 725 GTMGHGLPGQKGEHGERG 742 G+ GLPG KG+ G+ G Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436 Score = 397 bits (1021), Expect = e-110 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287 C KG+ G PG PGT G PGI G G KG G K G G GP G+ Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184 Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333 PG G G G G PG G G+ GP GP KG RG++G+TGPPG P Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244 Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371 G KG +G GEPGPPGP G P GAP G G++G+ G++ Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302 Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411 G PG PG GV G G PG G +G+ G++G G EG PGP Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452 G +G+ GP GP G G+ +KG KG+ G G + MG PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421 Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498 G G+ G GPPGP G P GLPG G G G GP+G G+ Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558 + GP G PG GL G G+PG GAAG KG G PG G G P G PG +GD G KG Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539 Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613 KG +GQ G+PG G +G+PG G G+PGT + G PGPKG+ G G +G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668 G G GP GP G PG G PG+ G +G+PG PGP G G T G Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657 Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724 PG GPPG GP+G G G G G GLPGP PG PG G G G +G QGFPG K Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755 G++G GLPG KGE G G G++G+ GE GE Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777 Query: 756 -PGSPGKQGLQGPKGDLG 772 PG+PG +GL GP+GD G Sbjct: 778 LPGTPGNEGLDGPRGDPG 795 Score = 390 bits (1002), Expect = e-108 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 C+ KG+ G+ G PG G+PG KG GP+G P G G +G G+PG G KG RG Sbjct: 41 CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG G G PG G GP G+ G+ PG G +G +G PG PG G PG PG Sbjct: 96 SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149 Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406 G +G KG +G G PGAPGP G+ G PG PGP GP G PG G PG Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439 P G KGE+G +G TGP G G I KG+KG +G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457 GP GP G+PG +G G + Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498 G +G IGPPG +GP +G PG G G GP GP GP G+ G Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389 Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551 ++G G PG G G+ G PG+D G+ G G GLPG+ GP GPPG + GP G Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449 Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587 D G G G+ G+PG +GPKGEPG++ GP G+PG Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506 Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636 PG PG G G PG PG +G+PG L G GV G G G PG KG Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 DG PG PG +GLPGP G + L G GD G G+PG G PGP+GP G GP+G+ G Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719 +G PGPPGPPG+ G G G+ G G Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686 Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 PGP G G G PG KG+ G G G G G++GEPG PGK GL G KG+ Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Score = 390 bits (1001), Expect = e-108 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%) Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299 +KG G+PGPPG G PG E+G G+PG +G+ G+ G G PG +G KG RG Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G+ GIKG KG GP G +GP +G +G GPPG G +G QG G PG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399 G GS PG G G G+KG +G+ GRP G PG G G PG PG GP G PG+ Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440 Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448 +G PG+ G PG G G G GP+G GL I G G G G G GI Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502 P G QG G++G G PG G P G PG++G+ G G G P G VG+ G G Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553 +G+PG GL G PG PG G G KGE L G +G +GPPG G PGP G Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G +G G QG +G+PG GP GE G G + T +PGPPGP G G PG G G PG Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660 G G G GP G PG+ G G+PG PGP+G G PG G G Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719 G GAKGEP V P GP P G +G G+ G+ GLPG PG PG G++G+ G +G G Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795 Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753 PGP G G GL G KG+ G RG G KGD GE Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855 Query: 754 GEPGSPGKQGLQGPKGDLG 772 G PG PG QG GP G G Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874 Score = 294 bits (752), Expect = 4e-79 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%) Query: 243 EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297 +KG+PG PGPPG G+PG+ G+ G KG G Q G G GP G G G G Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 298 GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354 G GKPG GD KG G GP G RG G+ G PG PGP G +G++G G PGP G Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169 Query: 355 GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402 G G+ G QG KG+RG G PG PG G +G+ G GP G EG PG GL Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229 Query: 403 PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452 PG G PG +G G+ GP GP G + IKG+KG +G GP+GP G G +G Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 453 SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507 G G G G PGP+G G QG PG KGE G +G GP GP+G G G +G+PG Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349 Query: 508 SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560 ++ G PG PG PGE G G+ G G PG GP GP GK G+ G G G G KG Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588 N+G +G PGP G G PG+ G G G+ Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 214 bits (544), Expect = 5e-55 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%) Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560 G KGE G G PG PG PG+ G G +G LPG +GP KG PG G G KG +G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620 G G G G G PG GP+G+ G +PG G KG++G PG+PG G PG+ Sbjct: 95 ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147 Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670 G G +G GAP KGD G PG PGP+GLPGPPG G G G G G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207 Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718 GP GP G G G KG+ G KGL GPPGPPG +G KG++G Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 G PGP G G LPG+ E G GD G +G G+ G PG PG +G++G +G GL E Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 777 EIIK 780 + IK Sbjct: 326 DGIK 329 Score = 99.8 bits (247), Expect = 1e-20 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296 KG+ G+PG G+ G PG G +GP +G+PG + G G G G PG +G+ Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG GP GPRG G G PG PGP G +GNKG G PGP GS G Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425 Query: 357 PGIGQQGIKGERGQEGRP 374 P G+KG+RG G P Sbjct: 1426 P-----GLKGKRGDSGSP 1438 Score = 89.7 bits (221), Expect = 1e-17 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%) Query: 245 GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 G G GPPG G+PG + G GP G PG + G GE GP G PG G G RG Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 KPG G G+PGP G KG +G +G GP G G G +G +G+ G P + + G Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 81.3 bits (199), Expect = 5e-15 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306 PG PGPPGT G PG++GE GP G PGN G G RG G G G G GE G G K Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338 G+ G G G G +G +G +G P +GF Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788 G G+KGE G G G G KG G G PG QG +G G GLT + ++ I+ + G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814 G P LV V S S G + F Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 431 bits (1109), Expect = e-120 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%) Query: 244 KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295 +GDPG PGPPG G PG I+G RG +G PG Q+G G+ GP G PG G G Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 GE G PGI G +G GP G +G G GI GPPG+ G G G G GPPGP G+PG Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 356 APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389 PG G GI G +GQ G PGA PGP + G PG+ G Sbjct: 911 TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Query: 390 PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435 RG G+PG +GL G G PGP+G+ GS G G GL+G+ KG++G Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030 Query: 436 DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 +G G G G+PGI G QG++G G PGP GP G GLPG G+ G+MG GP Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543 G +G G +G G PGS GLPG+PG G+ G G KG G PG RGP G PG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 544 ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569 KG+ PGP+G+ G +G+KG++G G PG Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210 Query: 570 ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620 P GP G G GP G+PG IPG G P G RG PG PG G PG + I+G K Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 621 GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675 G G GP G PG GD P G PG GLPGP G G +G G G KG PG G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 676 GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728 GP GP +G +GP G G G LPG PGPPG G G++GE GP G PG G G Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Query: 729 -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G PG+ G+ G G G+KG+KG GEPG G GL G KG G Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 422 bits (1084), Expect = e-117 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 EKGD G PGPPG G G +G GP G PG+ G RG G PG KG KGERG GK Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 303 --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344 PG+ G G PGP G KGP G G+ G G PG G G KGE Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471 Query: 345 PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391 PG PGP G PG PG+ G +GI G +G +G PG+PG G+ G PG PG + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 392 GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433 G G+ GE+G +PG+ G PG KG G G G +GL G L++ GE Sbjct: 532 GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591 Query: 434 KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484 KGD GP G P GP G PG G QGE G+QG G PG GP G+ G +GE+ Sbjct: 592 KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649 Query: 485 QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528 GP GP GP G G QGP G PGS+G G PG+PG D G G KG Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 529 EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579 + G PG +G G PGK G+PG G G G+K G G G PG G GE G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 580 MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623 +G G+PG +PG P GP+GD G PG PG +G PG I GP+G Q Sbjct: 770 IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827 Query: 624 --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675 GP+G G PGL G+PG G G+PG G MG +G G G PG+ GPP Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885 Query: 676 GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724 G G P +G GP G+ G G G PG PG G+ G KGEQG +G PGP Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944 Query: 725 GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774 + H + G KGE G +G G G+KG G PG PG +GL+ GP+GDLG T Sbjct: 945 SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Score = 411 bits (1057), Expect = e-114 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293 C + G+PG PG PG PG KGE G G PG ++G +GE G G+PG G Sbjct: 722 CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G G G +GD G PGP G +GP G I+G G G PG G +G +G G GP Sbjct: 779 PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404 G PG PG+ + G GE G G PG G +G G PG GP G +GV G G PG Sbjct: 839 GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456 G PGP G G+ G G G+ G +KG++G G G QG G PG IG +GE Sbjct: 899 AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956 Query: 457 QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514 G++G G PG +G G G+PG KG G GP GP GP G +G G GEPG G+PG Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 515 PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556 G G G+ GK+G G PG G G PG G PGP GD G Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600 G G +G+ G PGP G G G G G PG+ +PG PGP GD R Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 601 GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648 G PG+PGF G PG + IRG +G G GP G PG +G+ G G G RG Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701 PG PG G +G +GD G +G G+ G PGP G P G +GP G G G PGPP Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 702 GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751 GPPG GIKG++G G PGPKG G G PG G G RGD G +G G Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316 Query: 752 EIGEPGSPGKQGLQGPKGDLG 772 GE G+PG G GP G +G Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337 Score = 408 bits (1048), Expect = e-113 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298 ++G PG PG G G PG KGE+G KGNPG ++ G+ GE G G G G+KG RG Sbjct: 914 QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347 G PG+KG KG PGP GP GPRG G TG PG+PG +G GN G PG Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033 Query: 348 -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403 PG G PG PGI G QG KGE G EG RPG PGP G+PG PG G +G G+ G P Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091 Query: 404 G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451 G EG PG G G G GP G L KG KG +GP G +GP G+PG Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 452 -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486 G QG GI GP G PPGP+G G G PG G G M Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 487 GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545 G GPRGP GI G GP G PG+I +PG+ G G G G PGA GP GPPG Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262 Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605 G KGD KGS G+ G +G PG G G PG +G G PG +PGP G G +G PG+ Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317 Query: 606 PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665 G KG PG G G GP GP G PG++GD PG LPG PGP G Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365 Query: 666 KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724 GEPG++G PGP GP G +G GP+G G+ G PG PGP G KG +G +G PGP Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420 Query: 725 GTMGHGLPGQKGEHGERG 742 G+ GLPG KG+ G+ G Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436 Score = 397 bits (1021), Expect = e-110 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287 C KG+ G PG PGT G PGI G G KG G K G G GP G+ Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184 Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333 PG G G G G PG G G+ GP GP KG RG++G+TGPPG P Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244 Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371 G KG +G GEPGPPGP G P GAP G G++G+ G++ Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302 Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411 G PG PG GV G G PG G +G+ G++G G EG PGP Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452 G +G+ GP GP G G+ +KG KG+ G G + MG PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421 Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498 G G+ G GPPGP G P GLPG G G G GP+G G+ Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558 + GP G PG GL G G+PG GAAG KG G PG G G P G PG +GD G KG Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539 Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613 KG +GQ G+PG G +G+PG G G+PGT + G PGPKG+ G G +G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668 G G GP GP G PG G PG+ G +G+PG PGP G G T G Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657 Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724 PG GPPG GP+G G G G G GLPGP PG PG G G G +G QGFPG K Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755 G++G GLPG KGE G G G++G+ GE GE Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777 Query: 756 -PGSPGKQGLQGPKGDLG 772 PG+PG +GL GP+GD G Sbjct: 778 LPGTPGNEGLDGPRGDPG 795 Score = 390 bits (1002), Expect = e-108 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 C+ KG+ G+ G PG G+PG KG GP+G P G G +G G+PG G KG RG Sbjct: 41 CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG G G PG G GP G+ G+ PG G +G +G PG PG G PG PG Sbjct: 96 SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149 Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406 G +G KG +G G PGAPGP G+ G PG PGP GP G PG G PG Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439 P G KGE+G +G TGP G G I KG+KG +G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457 GP GP G+PG +G G + Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498 G +G IGPPG +GP +G PG G G GP GP GP G+ G Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389 Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551 ++G G PG G G+ G PG+D G+ G G GLPG+ GP GPPG + GP G Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449 Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587 D G G G+ G+PG +GPKGEPG++ GP G+PG Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506 Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636 PG PG G G PG PG +G+PG L G GV G G G PG KG Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 DG PG PG +GLPGP G + L G GD G G+PG G PGP+GP G GP+G+ G Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719 +G PGPPGPPG+ G G G+ G G Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686 Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 PGP G G G PG KG+ G G G G G++GEPG PGK GL G KG+ Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Score = 390 bits (1001), Expect = e-108 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%) Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299 +KG G+PGPPG G PG E+G G+PG +G+ G+ G G PG +G KG RG Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G+ GIKG KG GP G +GP +G +G GPPG G +G QG G PG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399 G GS PG G G G+KG +G+ GRP G PG G G PG PG GP G PG+ Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440 Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448 +G PG+ G PG G G G GP+G GL I G G G G G GI Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502 P G QG G++G G PG G P G PG++G+ G G G P G VG+ G G Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553 +G+PG GL G PG PG G G KGE L G +G +GPPG G PGP G Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G +G G QG +G+PG GP GE G G + T +PGPPGP G G PG G G PG Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660 G G G GP G PG+ G G+PG PGP+G G PG G G Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719 G GAKGEP V P GP P G +G G+ G+ GLPG PG PG G++G+ G +G G Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795 Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753 PGP G G GL G KG+ G RG G KGD GE Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855 Query: 754 GEPGSPGKQGLQGPKGDLG 772 G PG PG QG GP G G Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874 Score = 294 bits (752), Expect = 4e-79 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%) Query: 243 EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297 +KG+PG PGPPG G+PG+ G+ G KG G Q G G GP G G G G Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 298 GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354 G GKPG GD KG G GP G RG G+ G PG PGP G +G++G G PGP G Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169 Query: 355 GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402 G G+ G QG KG+RG G PG PG G +G+ G GP G EG PG GL Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229 Query: 403 PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452 PG G PG +G G+ GP GP G + IKG+KG +G GP+GP G G +G Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 453 SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507 G G G G PGP+G G QG PG KGE G +G GP GP+G G G +G+PG Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349 Query: 508 SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560 ++ G PG PG PGE G G+ G G PG GP GP GK G+ G G G G KG Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588 N+G +G PGP G G PG+ G G G+ Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 214 bits (544), Expect = 5e-55 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%) Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560 G KGE G G PG PG PG+ G G +G LPG +GP KG PG G G KG +G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620 G G G G G PG GP+G+ G +PG G KG++G PG+PG G PG+ Sbjct: 95 ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147 Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670 G G +G GAP KGD G PG PGP+GLPGPPG G G G G G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207 Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718 GP GP G G G KG+ G KGL GPPGPPG +G KG++G Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 G PGP G G LPG+ E G GD G +G G+ G PG PG +G++G +G GL E Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 777 EIIK 780 + IK Sbjct: 326 DGIK 329 Score = 99.8 bits (247), Expect = 1e-20 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296 KG+ G+PG G+ G PG G +GP +G+PG + G G G G PG +G+ Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG GP GPRG G G PG PGP G +GNKG G PGP GS G Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425 Query: 357 PGIGQQGIKGERGQEGRP 374 P G+KG+RG G P Sbjct: 1426 P-----GLKGKRGDSGSP 1438 Score = 89.7 bits (221), Expect = 1e-17 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%) Query: 245 GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 G G GPPG G+PG + G GP G PG + G GE GP G PG G G RG Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 KPG G G+PGP G KG +G +G GP G G G +G +G+ G P + + G Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 81.3 bits (199), Expect = 5e-15 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306 PG PGPPGT G PG++GE GP G PGN G G RG G G G G GE G G K Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338 G+ G G G G +G +G +G P +GF Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788 G G+KGE G G G G KG G G PG QG +G G GLT + ++ I+ + G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814 G P LV V S S G + F Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 431 bits (1109), Expect = e-120 Identities = 279/645 (43%), Positives = 328/645 (50%), Gaps = 118/645 (18%) Query: 244 KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295 +GDPG PGPPG G PG I+G RG +G PG Q+G G+ GP G PG G G Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 GE G PGI G +G GP G +G G GI GPPG+ G G G G GPPGP G+PG Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 356 APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389 PG G GI G +GQ G PGA PGP + G PG+ G Sbjct: 911 TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Query: 390 PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435 RG G+PG +GL G G PGP+G+ GS G G GL+G+ KG++G Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030 Query: 436 DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 +G G G G+PGI G QG++G G PGP GP G GLPG G+ G+MG GP Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG------- 543 G +G G +G G PGS GLPG+PG G+ G G KG G PG RGP G PG Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 544 ------------------KGQ-------PGPKGDEGKKGSKGNQGQRGLPG--------- 569 KG+ PGP+G+ G +G+KG++G G PG Sbjct: 1151 MGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMG 1210 Query: 570 ---PEGPKGEPGIMGPFGMPGTSIPGPPG---PKGDRGGPGIPGFKGEPG---LSIRGPK 620 P GP G G GP G+PG IPG G P G RG PG PG G PG + I+G K Sbjct: 1211 DAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 621 GVQGPRGPVGAPGLKGDGYP----GVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPP 675 G G GP G PG GD P G PG GLPGP G G +G G G KG PG G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 676 GPSGPRGVGTQGPKGDTGQKG------LPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMG 728 GP GP +G +GP G G G LPG PGPPG G G++GE GP G PG G G Sbjct: 1331 GPPGP--IGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCG 1388 Query: 729 -HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G PG+ G+ G G G+KG+KG GEPG G GL G KG G Sbjct: 1389 PRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433 Score = 422 bits (1084), Expect = e-117 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 EKGD G PGPPG G G +G GP G PG+ G RG G PG KG KGERG GK Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 303 --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344 PG+ G G PGP G KGP G G+ G G PG G G KGE Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471 Query: 345 PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391 PG PGP G PG PG+ G +GI G +G +G PG+PG G+ G PG PG + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 392 GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433 G G+ GE+G +PG+ G PG KG G G G +GL G L++ GE Sbjct: 532 GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591 Query: 434 KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484 KGD GP G P GP G PG G QGE G+QG G PG GP G+ G +GE+ Sbjct: 592 KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649 Query: 485 QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528 GP GP GP G G QGP G PGS+G G PG+PG D G G KG Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 529 EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579 + G PG +G G PGK G+PG G G G+K G G G PG G GE G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 580 MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623 +G G+PG +PG P GP+GD G PG PG +G PG I GP+G Q Sbjct: 770 IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827 Query: 624 --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675 GP+G G PGL G+PG G G+PG G MG +G G G PG+ GPP Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885 Query: 676 GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724 G G P +G GP G+ G G G PG PG G+ G KGEQG +G PGP Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944 Query: 725 GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774 + H + G KGE G +G G G+KG G PG PG +GL+ GP+GDLG T Sbjct: 945 SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Score = 411 bits (1057), Expect = e-114 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293 C + G+PG PG PG PG KGE G G PG ++G +GE G G+PG G Sbjct: 722 CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G G G +GD G PGP G +GP G I+G G G PG G +G +G G GP Sbjct: 779 PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404 G PG PG+ + G GE G G PG G +G G PG GP G +GV G G PG Sbjct: 839 GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456 G PGP G G+ G G G+ G +KG++G G G QG G PG IG +GE Sbjct: 899 AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956 Query: 457 QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514 G++G G PG +G G G+PG KG G GP GP GP G +G G GEPG G+PG Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 515 PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556 G G G+ GK+G G PG G G PG G PGP GD G Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600 G G +G+ G PGP G G G G G PG+ +PG PGP GD R Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 601 GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648 G PG+PGF G PG + IRG +G G GP G PG +G+ G G G RG Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701 PG PG G +G +GD G +G G+ G PGP G P G +GP G G G PGPP Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 702 GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751 GPPG GIKG++G G PGPKG G G PG G G RGD G +G G Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316 Query: 752 EIGEPGSPGKQGLQGPKGDLG 772 GE G+PG G GP G +G Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337 Score = 408 bits (1048), Expect = e-113 Identities = 257/558 (46%), Positives = 295/558 (52%), Gaps = 93/558 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298 ++G PG PG G G PG KGE+G KGNPG ++ G+ GE G G G G+KG RG Sbjct: 914 QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347 G PG+KG KG PGP GP GPRG G TG PG+PG +G GN G PG Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033 Query: 348 -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403 PG G PG PGI G QG KGE G EG RPG PGP G+PG PG G +G G+ G P Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091 Query: 404 G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451 G EG PG G G G GP G L KG KG +GP G +GP G+PG Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 452 -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486 G QG GI GP G PPGP+G G G PG G G M Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 487 GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545 G GPRGP GI G GP G PG+I +PG+ G G G G PGA GP GPPG Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262 Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605 G KGD KGS G+ G +G PG G G PG +G G PG +PGP G G +G PG+ Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317 Query: 606 PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665 G KG PG G G GP GP G PG++GD PG LPG PGP G Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365 Query: 666 KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPK 724 GEPG++G PGP GP G +G GP+G G+ G PG PGP G KG +G +G PGP Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE-----KGNKGSKGEPGPA 1420 Query: 725 GTMGHGLPGQKGEHGERG 742 G+ GLPG KG+ G+ G Sbjct: 1421 GS--DGLPGLKGKRGDSG 1436 Score = 397 bits (1021), Expect = e-110 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287 C KG+ G PG PGT G PGI G G KG G K G G GP G+ Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184 Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333 PG G G G G PG G G+ GP GP KG RG++G+TGPPG P Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244 Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371 G KG +G GEPGPPGP G P GAP G G++G+ G++ Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302 Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411 G PG PG GV G G PG G +G+ G++G G EG PGP Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452 G +G+ GP GP G G+ +KG KG+ G G + MG PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421 Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498 G G+ G GPPGP G P GLPG G G G GP+G G+ Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558 + GP G PG GL G G+PG GAAG KG G PG G G P G PG +GD G KG Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539 Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613 KG +GQ G+PG G +G+PG G G+PGT + G PGPKG+ G G +G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668 G G GP GP G PG G PG+ G +G+PG PGP G G T G Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657 Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724 PG GPPG GP+G G G G G GLPGP PG PG G G G +G QGFPG K Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755 G++G GLPG KGE G G G++G+ GE GE Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777 Query: 756 -PGSPGKQGLQGPKGDLG 772 PG+PG +GL GP+GD G Sbjct: 778 LPGTPGNEGLDGPRGDPG 795 Score = 390 bits (1002), Expect = e-108 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 C+ KG+ G+ G PG G+PG KG GP+G P G G +G G+PG G KG RG Sbjct: 41 CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG G G PG G GP G+ G+ PG G +G +G PG PG G PG PG Sbjct: 96 SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149 Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406 G +G KG +G G PGAPGP G+ G PG PGP GP G PG G PG Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439 P G KGE+G +G TGP G G I KG+KG +G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457 GP GP G+PG +G G + Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498 G +G IGPPG +GP +G PG G G GP GP GP G+ G Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389 Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551 ++G G PG G G+ G PG+D G+ G G GLPG+ GP GPPG + GP G Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449 Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587 D G G G+ G+PG +GPKGEPG++ GP G+PG Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506 Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636 PG PG G G PG PG +G+PG L G GV G G G PG KG Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 DG PG PG +GLPGP G + L G GD G G+PG G PGP+GP G GP+G+ G Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719 +G PGPPGPPG+ G G G+ G G Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686 Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 PGP G G G PG KG+ G G G G G++GEPG PGK GL G KG+ Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Score = 390 bits (1001), Expect = e-108 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%) Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299 +KG G+PGPPG G PG E+G G+PG +G+ G+ G G PG +G KG RG Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G+ GIKG KG GP G +GP +G +G GPPG G +G QG G PG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399 G GS PG G G G+KG +G+ GRP G PG G G PG PG GP G PG+ Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440 Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448 +G PG+ G PG G G G GP+G GL I G G G G G GI Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502 P G QG G++G G PG G P G PG++G+ G G G P G VG+ G G Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553 +G+PG GL G PG PG G G KGE L G +G +GPPG G PGP G Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G +G G QG +G+PG GP GE G G + T +PGPPGP G G PG G G PG Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660 G G G GP G PG+ G G+PG PGP+G G PG G G Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719 G GAKGEP V P GP P G +G G+ G+ GLPG PG PG G++G+ G +G G Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795 Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753 PGP G G GL G KG+ G RG G KGD GE Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855 Query: 754 GEPGSPGKQGLQGPKGDLG 772 G PG PG QG GP G G Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874 Score = 294 bits (752), Expect = 4e-79 Identities = 175/388 (45%), Positives = 208/388 (53%), Gaps = 44/388 (11%) Query: 243 EKGDPG-----DPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297 +KG+PG PGPPG G+PG+ G+ G KG G Q G G GP G G G G Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG--QPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 298 GECGKPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354 G GKPG GD KG G GP G RG G+ G PG PGP G +G++G G PGP G Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169 Query: 355 GAPGI-----------GQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGL 402 G G+ G QG KG+RG G PG PG G +G+ G GP G EG PG GL Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGL 1229 Query: 403 PG---------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IG 452 PG G PG +G G+ GP GP G + IKG+KG +G GP+GP G G +G Sbjct: 1230 PGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 453 SQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQ---MGPTGPRGPVGI-GVQGPKGEPG 507 G G G G PGP+G G QG PG KGE G +G GP GP+G G G +G+PG Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349 Query: 508 SI------GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGPKGDEGKKGSKG 560 ++ G PG PG PGE G G+ G G PG GP GP GK G+ G G G G KG Sbjct: 1350 TLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGT 588 N+G +G PGP G G PG+ G G G+ Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 214 bits (544), Expect = 5e-55 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%) Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560 G KGE G G PG PG PG+ G G +G LPG +GP KG PG G G KG +G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620 G G G G G PG GP+G+ G +PG G KG++G PG+PG G PG+ Sbjct: 95 ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147 Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670 G G +G GAP KGD G PG PGP+GLPGPPG G G G G G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207 Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718 GP GP G G G KG+ G KGL GPPGPPG +G KG++G Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 G PGP G G LPG+ E G GD G +G G+ G PG PG +G++G +G GL E Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 777 EIIK 780 + IK Sbjct: 326 DGIK 329 Score = 99.8 bits (247), Expect = 1e-20 Identities = 59/138 (42%), Positives = 71/138 (51%), Gaps = 24/138 (17%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGP---KGNPGNAQ----KGEAGERGPGGIPGYKGDKGE 296 KG+ G+PG G+ G PG G +GP +G+PG + G G G G PG +G+ Sbjct: 1318 KGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE--- 1374 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 G G PG GP GPRG G G PG PGP G +GNKG G PGP GS G Sbjct: 1375 ---------PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGL 1425 Query: 357 PGIGQQGIKGERGQEGRP 374 P G+KG+RG G P Sbjct: 1426 P-----GLKGKRGDSGSP 1438 Score = 89.7 bits (221), Expect = 1e-17 Identities = 50/117 (42%), Positives = 61/117 (52%), Gaps = 11/117 (9%) Query: 245 GDPGDPGPPGTHGNPG------IKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 G G GPPG G+PG + G GP G PG + G GE GP G PG G G RG Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPG--EPGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 KPG G G+PGP G KG +G +G GP G G G +G +G+ G P + + G Sbjct: 1392 ---KPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 81.3 bits (199), Expect = 5e-15 Identities = 43/92 (46%), Positives = 50/92 (54%), Gaps = 2/92 (2%) Query: 247 PGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306 PG PGPPGT G PG++GE GP G PGN G G RG G G G G GE G G K Sbjct: 1357 PGSPGPPGTPGEPGMQGEPGPPGPPGNL--GPCGPRGKPGKDGKPGTPGPAGEKGNKGSK 1414 Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338 G+ G G G G +G +G +G P +GF Sbjct: 1415 GEPGPAGSDGLPGLKGKRGDSGSPATWTTRGF 1446 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788 G G+KGE G G G G KG G G PG QG +G G GLT + ++ I+ + G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814 G P LV V S S G + F Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 431 bits (1107), Expect = e-120 Identities = 287/640 (44%), Positives = 330/640 (51%), Gaps = 126/640 (19%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG----------------PG-- 285 +G PG GPPG G PGIKGE+G G PG G G++G PG Sbjct: 807 RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866 Query: 286 ---GIPGYKGDKGERGECG---KPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQ 339 GIPG+ G KGE G G +PG G G+PG G KG G G +GP GDPG KG + Sbjct: 867 GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDK 926 Query: 340 GNKGEPGPPGPY------------GSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEP 385 G+ G PG PG G G G IG G KG RG G PG PG G G+P Sbjct: 927 GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQP 986 Query: 386 GQPGPRGPEGV---PGERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGL-SIKGEK 434 GQPGP+G G+ PG GLPG G PG GEKG G GPQG GL KG K Sbjct: 987 GQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAK 1046 Query: 435 GDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGP 494 G+ G GP G +GIPG+ +GE+G QG G PG PG KGE G +G G G Sbjct: 1047 GEKGQAGPPG-IGIPGL--RGEKGDQGIAGFPGS--------PGEKGEKGSIGIPGMPGS 1095 Query: 495 VGIGVQGPKGEPGSIGLPGQPGVPGE---------DGAAGKKGEAGLPGARGPEGPPG-K 544 G+ KG PGS+G PG PG+PGE DG G KGEAGLPG GP GP G K Sbjct: 1096 PGL-----KGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150 Query: 545 GQPGPKGDEGKKGSKGNQGQ--RGLPGPEGPKGEPGIMGPFGMPGTS-IPGPPGPKGDRG 601 G+PG G G G KG G RG PG G KG+ G G G PG + PG PG KG++G Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQG 1210 Query: 602 GPGIPGFKGEPGL------SIRGPKGVQGPRGPVGAPGL---------------KGD-GY 639 G PG +G+PGL + GPKG +GP+G G PGL KGD G Sbjct: 1211 FMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGN 1270 Query: 640 PGVPGPRGLPGPPGPMGLRGV-------GDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGD 691 PG PG G+PGP G G +G+ G TG+KG+ G G PG GP+G+ G QG KGD Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330 Query: 692 TGQ------KGLPGPPGPPG-----YGSQGIKGEQGP------QGFPGPKGTMG-HGLPG 733 G KGLPGPPGPPG G G+ G +GP QG PGPKG G GL G Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390 Query: 734 QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G G G G G KGE+G G G +G GP G GL Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL 1430 Score = 425 bits (1092), Expect = e-118 Identities = 296/727 (40%), Positives = 337/727 (46%), Gaps = 199/727 (27%) Query: 243 EKGDPGDPGPPG--------------THGNPGIKGERGPKGNPGNAQKGEAGERGPGGIP 288 +KGD G GPPG T G G KGE G +G PG +KGE G+ GP G P Sbjct: 230 DKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKP 289 Query: 289 GYKGDKGERGECGKPGI------------KGDKGSPGPYGP------------KGPRGIQ 324 G GDKGE+G G PG +G+KG GP GP KG RG Sbjct: 290 GKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYP 349 Query: 325 GITGPPGDPGPKGFQGNKGEPGPPG--PYGSPGAPGI-GQQGIKGER--------GQEGR 373 G GP G+PGPKGF G G+PGPPG G GAPG G++G KG+R G GR Sbjct: 350 GTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409 Query: 374 PGAPGPIG-VGEPGQP-------------------------------------------- 388 G PGP G G PGQP Sbjct: 410 DGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLI 469 Query: 389 -------GPRGPEGVPGERGLPGE-------GFPGPKGEKGSEGPTGPQGLQG------- 427 GP GP+G PGE G PG+ G PG G G GP G GL G Sbjct: 470 CDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGE 529 Query: 428 -------LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAGQ-GLPG 478 L +KG+KGD G G G G G G G G+ GP G PG G G+ G PG Sbjct: 530 PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPG 589 Query: 479 SKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE-AGLPGARG 537 G G G TGP GP G G GP G+ G G PG PG PG G G+ G+ LPG G Sbjct: 590 GVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPG 649 Query: 538 PEGPPGK-GQPGPKGDE---------GKKGSKGNQGQRGL--PGPEGPKGEPGIMGPFGM 585 EG PG G PGP+GD G G KG GQ G+ PGP GPKG G+ G G Sbjct: 650 AEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGP 709 Query: 586 PGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPG 644 PGT PG PG G G PG+ G KGEPG+ + G KG+ G G G PG KG G PGVPG Sbjct: 710 PGT--PGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPG 767 Query: 645 PRGLPGPPGPMGLR------------------GVGDTGAKGEPGVRGPPGPSGPRGVGTQ 686 G GPPG G+R G+G GA+G PG +GPPG SGP G+ + Sbjct: 768 EHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGE 827 Query: 687 ------------GPKGD---------TGQKGLPGPPGPPGY----GSQGIKGEQGPQGFP 721 GPKGD TGQ GLPG PG G G G KGE G G P Sbjct: 828 KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887 Query: 722 GPKGTMG----HGLPGQKGEH------GERGDVGKKGDKGEIGEPGSPGKQ------GLQ 765 G G+ G GLPG+KG+H G RGD G KGDKG++G PG PG ++ Sbjct: 888 GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMK 947 Query: 766 GPKGDLG 772 G KGD G Sbjct: 948 GQKGDQG 954 Score = 425 bits (1092), Expect = e-118 Identities = 274/615 (44%), Positives = 319/615 (51%), Gaps = 95/615 (15%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK-----GDKGERG- 298 G PG PGP G+ G+ G+KGERGP G G G G+ GP G PGY GDKG+ G Sbjct: 565 GHPGLPGPKGSPGSVGLKGERGPPGGVGFP--GSRGDTGPPGPPGYGPAGPIGDKGQAGF 622 Query: 299 --ECGKPGIKGDKGSPGPYGP-KGPRGIQGITGPPGDPGP---KGFQGNKGEPGPPGPYG 352 G PG+ G KG PG P GP G +G+ G PG PGP +GF G G PG PG G Sbjct: 623 PGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKG 682 Query: 353 SPGAPGIGQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEG-----VPGER 400 + G PGIG G G +G +G PG GP G G PG PG +G +G +PG + Sbjct: 683 AVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLK 742 Query: 401 GLPG-EGFPGPKGEKGS---------EGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG 450 GLPG G PG GEKGS G GP GLQG I+GE G G G G G+PG Sbjct: 743 GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQG--IRGEPGPPGLPGSVGSPGVPG 800 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG------------------------QGLPGSKGEVGQM 486 IG G +G G GPPG GP G QGLPG G+ G Sbjct: 801 IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLP 860 Query: 487 GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAG---KKGEAGLPGARGPEGPP 542 G G +G GI G G KGE G +G PGQPG PG GA G +KG+ G PG+ GP G P Sbjct: 861 GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDP 920 Query: 543 G-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT----SIPGPPGPK 597 G KG G G GK GS + G +G +GE G +GP G G+ PG PG Sbjct: 921 GLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKD 980 Query: 598 GDRGGPGIPGFKGEPGLS-IRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMG 656 G G PG PG KG+PG+S G G+ GP+G VG GL PG PG +G+PG PGP G Sbjct: 981 GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL-----PGTPGEKGVPGIPGPQG 1035 Query: 657 LRGV-GDTGAKGEPGVRGPPG--------PSGPRGV----GTQGPKGDTGQKGLPGPPGP 703 G+ GD GAKGE G GPPG G +G+ G+ G KG+ G G+PG PG Sbjct: 1036 SPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS 1095 Query: 704 PGY-GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGS 758 PG GS G G G G PG KG G G+PG KGE G G G G G+ GEPGS Sbjct: 1096 PGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS 1155 Query: 759 PGKQGLQGPKGDLGL 773 G G G KG+ GL Sbjct: 1156 DGIPGSAGEKGEPGL 1170 Score = 422 bits (1086), Expect = e-118 Identities = 269/633 (42%), Positives = 321/633 (50%), Gaps = 104/633 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKG------- 295 + G PG PG PG +G PG G +G KG PG G G G GIPG G+KG Sbjct: 706 DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGV 765 Query: 296 --ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITG--PPGDPGPKGFQGNKGEPGPPGPY 351 E G G PG++G +G PGP G G G G+ G PPG GP G QG G GPPG Sbjct: 766 PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIK 825 Query: 352 GSPGAPGI------------GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPG 398 G G PG G QG+ G GQ G PG PG G G PG PG +G GV G Sbjct: 826 GEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMG 885 Query: 399 ERGLPGE-------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI 451 G PG G PG KG+ G G +GP+G GL KG+KGD+G G G M + Sbjct: 886 TPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL--KGDKGDVGLPGKPGSMDKVDM 943 Query: 452 GS-------QGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTGPRGPVGI------ 497 GS QGE+G GPIG G +G P G+PG G+ GQ G GP+G GI Sbjct: 944 GSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGA 1003 Query: 498 -GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK 556 G+ GPKG G +GLPG PG G G G +G GLPG +G +G G+ P G G + Sbjct: 1004 PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-------------SIPGPPGPKGDRGGP 603 G KG+QG G PG G KGE G +G GMPG+ PG PG KGD+G P Sbjct: 1064 GEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLP 1123 Query: 604 G---IPGFKGEPGL-------------SIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRG 647 G IPG KGE GL G G+ G G G PGL G G+PG PG +G Sbjct: 1124 GLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG 1183 Query: 648 LPGPPGPMGLRGV----GDTGAKGEPGVRGPPGPSGPRGV------GTQGPKGDTGQKG- 696 G G +G G+ G G+KGE G GPPGP G G+ T+GPKGD G +G Sbjct: 1184 DKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ 1243 Query: 697 -----LPGPPGPPGY-GSQGIKGEQGPQGFPG------PKGTMGH----GLPGQKGEHGE 740 LPGP GPPG G G+KG++G G+PG PKG G G+ G G G Sbjct: 1244 PGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGS 1303 Query: 741 RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 +GD+G G G G G PG QG++G +GD G+ Sbjct: 1304 KGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGV 1336 Score = 420 bits (1080), Expect = e-117 Identities = 278/679 (40%), Positives = 324/679 (47%), Gaps = 148/679 (21%) Query: 234 KCERKICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGD 293 KC+ + +KG+ G PG G G PG++G GP+G PG QKG+ GE G G G +G Sbjct: 38 KCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPG--QKGDTGEPGLPGTKGTRGP 95 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353 G G G PG+ G G GP GP G G G G G GP G G G PGPPG G Sbjct: 96 PGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGM 155 Query: 354 PGAPG-----IGQQGIKGERGQEGRPGAPGPIG-------VGEP---GQPGPRGPEGVPG 398 G PG + +KGERG G PG PGP G VG P G PGP GP G PG Sbjct: 156 KGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215 Query: 399 ERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDI------GPVGPQGPMGIPGIG 452 E+G G F GPKG+KG +G +GP G+ G + EKGD G G G G+PG+G Sbjct: 216 EKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVG 275 Query: 453 SQGEQGIQGPIGPPGPQGPAGQ-------------GLPGSKGEVGQMGPTGPRGPVGI-- 497 +GE G GP G PG G G+ GL G +G G+ G GP GP GI Sbjct: 276 EKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVI 335 Query: 498 --------------GVQGPKGEPGSIGLPGQPG--------VPGEDGAAGKKGEA----- 530 G GP+GEPG G PG PG VPG+ GA G GE Sbjct: 336 GTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGD 395 Query: 531 ---------------GLPGARGPEGPPGKG---------QPGPKGDE------------- 553 GLPG G GPPG+ QPGP GD+ Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 455 Query: 554 --GKKGSKGN-------QGQRGLPGPEGPKGE------PGIMGPFGMPG-TSIPGPPGPK 597 G+KG KG G RG PGP+GP GE PG G G+PG + G PGP+ Sbjct: 456 EIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQ 515 Query: 598 GDRGGPGIPGFKGEPG-----LSIRGPKGVQGPRGPVGAPGLKG----DGYPGVPGPRGL 648 G G G PG KGEPG L ++G KG G G G G G DG+PG+PGP+G Sbjct: 516 GTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGS 575 Query: 649 PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-- 706 PG G G R G G G PG RG GP GP G G GP GD GQ G PG PG PG Sbjct: 576 PGSVGLKGER--GPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPG 633 Query: 707 ------------GSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEI 753 G G +G G GFPGP+G G G PG+ G GE+G VG+ G I Sbjct: 634 PKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG----I 689 Query: 754 GEPGSPGKQGLQGPKGDLG 772 G PG PG +G+ G GD+G Sbjct: 690 GFPGPPGPKGVDGLPGDMG 708 Score = 418 bits (1074), Expect = e-116 Identities = 272/645 (42%), Positives = 314/645 (48%), Gaps = 129/645 (20%) Query: 245 GDPGDPGP------PGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 G PG PGP PGT G PG+ GE+G G PG G G GP G+ G GD G G Sbjct: 655 GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI---GFPGPPGPKGVDGLPGDMGPPG 711 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGI-----QGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353 G+PG G G+PG G KG G+ +G+ G PG PG G +G+ G PG PG +G+ Sbjct: 712 TPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGA 771 Query: 354 PGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGE 413 G PG+ QGI+GE G G PG+ G GV G PG RGP G G GL G PG KGE Sbjct: 772 IGPPGL--QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGP--PGIKGE 827 Query: 414 KG--------SEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463 KG GP G +G QGL I G+ G G G QG GIPG GS+GE G+ G Sbjct: 828 KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887 Query: 464 GPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI------------------------- 497 G PG GP G GLPG KG+ G G +GPRG G+ Sbjct: 888 GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMK 947 Query: 498 ---------GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQP 547 G GP GE GS G PG PGVPG+DG AG+ G+ G G G G PG G P Sbjct: 948 GQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLP 1007 Query: 548 GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP--------------FGMPG------ 587 GPKG G G G G++G+PG GP+G PG+ G G+PG Sbjct: 1008 GPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKG 1067 Query: 588 ----TSIPGPPGPKGDRGGPGIPGFKGEPGLS-------IRGPKGVQGPRGPVGAPGLKG 636 PG PG KG++G GIPG G PGL G G+ G +G G PGL Sbjct: 1068 DQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGL-- 1125 Query: 637 DGYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGEPGVRGPPGPSGPRGVGTQ 686 DG PGV G GLPG PGP G G G G KGEPG+ G P P G + Sbjct: 1126 DGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDK 1185 Query: 687 GPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVG 745 G KG+ G GL G PG PG G QG G GPQG PG G+ GH G KG+ G +G G Sbjct: 1186 GSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG 1245 Query: 746 K------------------KGDKGEIGEPGSPGKQGLQGPKGDLG 772 KGDKG PG PG G+ GPKGD G Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGN---PGWPGAPGVPGPKGDPG 1287 Score = 408 bits (1048), Expect = e-113 Identities = 261/585 (44%), Positives = 312/585 (53%), Gaps = 74/585 (12%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 KGD GDPG PG G G G G G+PG G +G G G KG++G G G P Sbjct: 540 KGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP-----GPKGSPGSVGLKGERGPPGGVGFP 594 Query: 304 GIKGDKGSPGP--YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG-------PPGPYGSP 354 G +GD G PGP YGP GP G +G G PG PG G G KGEPG PPG G P Sbjct: 595 GSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP 654 Query: 355 GAPGI-GQQGIKGERGQEGRPGAPGPIG------VGEPGQPGPRGPEGVPGERGLPGE-G 406 G+PG G QG +G G GRPG PG G +G PG PGP+G +G+PG+ G PG G Sbjct: 655 GSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPG 714 Query: 407 FPGPKGEKGSEGPTGPQGLQGLSIKGEKG------DIGPVGPQGPMGIPG-------IGS 453 PG G G+ G G +G G+ + G KG G G +G +G+PG IG Sbjct: 715 RPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGP 774 Query: 454 QGEQGIQGPIGPPGPQGPAGQ------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPG 507 G QGI+G GPPG G G G PG++G G GP G GP GI +G KG PG Sbjct: 775 PGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGI--KGEKGFPG 832 Query: 508 SIGL--PGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR 565 GL PG G G G G G++GLPG G +G PG PG G +G+ G G GQ Sbjct: 833 FPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGI--PGFPGSKGEMGVMGTPGQP 890 Query: 566 GLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGL----SIRGPK 620 G PGP G G PG G G PG+S P G PG KGD+G G+PG G S++G K Sbjct: 891 GSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQK 950 Query: 621 GVQGPRG---PVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPG 676 G QG +G P+G G +GD G PGVPG G G PG G +G D G G PG G PG Sbjct: 951 GDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG--DPGISGTPGAPGLPG 1008 Query: 677 PSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG 736 P G VG G G G+KG+PG PGP G S G+ G++G +G G G G G+PG +G Sbjct: 1009 PKG--SVGGMGLPGTPGEKGVPGIPGPQG--SPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064 Query: 737 EHGERGD---------VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 E +GD G+KG+KG IG PG PG GL+G G +G Sbjct: 1065 E---KGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106 Score = 398 bits (1023), Expect = e-110 Identities = 270/604 (44%), Positives = 299/604 (49%), Gaps = 85/604 (14%) Query: 239 ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA--------QKGEAGERGPGGIPGY 290 I EC+ G PGD GPPG G PG GE G KG G + +G G +GP G G+ Sbjct: 431 IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGF 490 Query: 291 KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPG-------------DPGPKG 337 G G +G+ G PG G G PGP G G G G G PG DPG G Sbjct: 491 PGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPG 550 Query: 338 FQGNKGEPGPPGPYGSPGAPGI----GQQGIKGERGQEGRPGAPGPIG-VGEPGQPG--P 390 G G G PG G PG PG G G+KGERG G G PG G G PG PG P Sbjct: 551 QPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGP 610 Query: 391 RGPEGVPGERGLPG----EGFPGPKGEKGSEGPT-GPQGLQGLSIKGEKGDIGPVGPQGP 445 GP G G+ G PG G PGPKGE G P GP G +GL G G GPQG Sbjct: 611 AGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP-----GSPGFPGPQGD 665 Query: 446 MGIPGI----GSQGEQGIQGP--IGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRG-PVGI 497 G PG G GE+G G IG PGP GP G GLPG G G G G G P Sbjct: 666 RGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNP 725 Query: 498 GVQGPKGEPGS-----IGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPG 548 GVQG KGEPG GLPG PG+PG G G G G+PG G GPPG +G+PG Sbjct: 726 GVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPG 785 Query: 549 PKGDEGKKGSKG-----NQGQRGLPGPEGP---KGEPGIMGPFGMPGTSIPGPPGPKGDR 600 P G G GS G G RG PG +GP G PGI G G PG PGPKGD+ Sbjct: 786 PPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDK 845 Query: 601 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV 660 G G+PG G+ GL G G QG G G PG KG+ GV G G PG PGP V Sbjct: 846 GAQGLPGITGQSGLP--GLPGQQGAPGIPGFPGSKGE--MGVMGTPGQPGSPGP-----V 896 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY----------GSQG 710 G G GE G G PG SGPRG G KGD G GLPG PG G QG Sbjct: 897 GAPGLPGEKGDHGFPGSSGPRG--DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQG 954 Query: 711 IKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKG 769 KG+ GP G G +G G G+PG+ G+ G+ G G KGD G G PG+PG G +G G Sbjct: 955 EKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVG 1014 Query: 770 DLGL 773 +GL Sbjct: 1015 GMGL 1018 Score = 378 bits (971), Expect = e-104 Identities = 252/605 (41%), Positives = 297/605 (49%), Gaps = 116/605 (19%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-------------AQKGEAGERGPGGIPG 289 EKGD G PG G G+PG+KG++G G PG QKG+ GE+G G G Sbjct: 904 EKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIG 963 Query: 290 YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349 KG +G+ G G PG G G PG GPKG GI G G PG PGPKG G G PG PG Sbjct: 964 EKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPG 1023 Query: 350 PYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGE--- 405 G PG PG G G+ G++G +G G GP G+G PG G +G +G+ G G PGE Sbjct: 1024 EKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGE 1083 Query: 406 -------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQ 457 G PG G KGS G G G GL GEKGD G G G IPG+ G G Sbjct: 1084 KGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP--GEKGDKGLPGLDG---IPGVKGEAGLP 1138 Query: 458 GIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG---PRGPVGIGVQGPKGEPGSIGLPG 513 G GP GP G +G P G+PGS GE G+ G G P P G +G KGE G GL G Sbjct: 1139 GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAG 1198 Query: 514 QPGVPGEDGAAG------KKGEAGLPGA-----------RGPEGPPG-------KGQPGP 549 PG+PG G G +G+ GLPG+ RGP+G PG G PG Sbjct: 1199 SPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGL 1258 Query: 550 KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFK 609 G +G KG KGN G G PG GPKG+PG G G+ G+ PG G KGD G PG+PGF+ Sbjct: 1259 PGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS--PGITGSKGDMGPPGVPGFQ 1316 Query: 610 GEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPR-------GLPGPPGPMGLRGV- 660 G GL G +G++G +G G PG KG G PG PGP GLPGP GP GL+G+ Sbjct: 1317 GPKGLP--GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQ 1374 Query: 661 ------------------------GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKG 696 G GA G+ G GP GP+GPRG GP G G G Sbjct: 1375 GLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGF--PGPPGPDGLPG 1432 Query: 697 LPGPPGPPGYG--------SQGIKGEQGPQGFPGPKGTMGHG-----LPGQKGEHGERGD 743 GPPG P SQ I Q P G + HG + G + HG+ D Sbjct: 1433 SMGPPGTPSVDHGFLVTRHSQTIDDPQCPSG----TKILYHGYSLLYVQGNERAHGQ--D 1486 Query: 744 VGKKG 748 +G G Sbjct: 1487 LGTAG 1491 Score = 298 bits (762), Expect = 3e-80 Identities = 206/496 (41%), Positives = 241/496 (48%), Gaps = 100/496 (20%) Query: 370 QEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGL 425 + R A G G+ G +G GERGLPG GFPG +G +G +GP G +G Sbjct: 21 EHSRAAAKGGCAGSGCGKCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGD 80 Query: 426 QG-LSIKGEKGDIGPV------------------GPQGPMGIPGIGSQGEQGIQGPIGPP 466 G + G KG GP GP GP GIP G G +G +GP+GPP Sbjct: 81 TGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIP--GCNGTKGERGPLGPP 138 Query: 467 GPQGPAGQ----GLPGSKGEVGQM----------------GPTGPRGPVGI-GVQGPKGE 505 G G AG GLPG KG+ G++ G G GP G+ G+QGP G Sbjct: 139 GLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGP 198 Query: 506 PGSIGLPGQPGVPGEDGAAGK--------KGEAGLPGARGPEGPPGKGQPGPKGD---EG 554 PG G PG PG PG G G+ KG+ G G GP G PG+ Q KGD +G Sbjct: 199 PGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKG 258 Query: 555 KKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL 614 +KG KG G +G+PG G KGEPG GP G PG G KG++G PG PG G PGL Sbjct: 259 EKGQKGEPGFQGMPG-VGEKGEPGKPGPRGKPGKD-----GDKGEKGSPGFPGEPGYPGL 312 Query: 615 SIR-GPKGVQGPRGPVGAPGL---------KGD-GYPGVPGPRGLPGP---------PGP 654 R GP+G +G GP G PG+ KG+ GYPG PGPRG PGP PGP Sbjct: 313 IGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372 Query: 655 MGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYG------- 707 GL G GA G PG RG G G G GP G G G PG PGPPG Sbjct: 373 PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV 432 Query: 708 --SQGIKGEQGPQGFPGPKGTMGH-GLPGQKGE-------HGERGDVGKKGDKGEIGEPG 757 G G+QGP G PG G +G G GQKGE G RG G +G GEIG PG Sbjct: 433 ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPG 492 Query: 758 SPGKQGLQGPKGDLGL 773 PG +G +G G G+ Sbjct: 493 QPGAKGDRGLPGRDGV 508 Score = 161 bits (407), Expect = 4e-39 Identities = 108/249 (43%), Positives = 122/249 (48%), Gaps = 39/249 (15%) Query: 241 ECEKGDPGD---------PGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYK 291 E KGD G PGP G G PGI G +G KGNPG G G GP G PG++ Sbjct: 1232 EGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG--WPGAPGVPGPKGDPGFQ 1289 Query: 292 GDKGERGECGKPGIKGDKGSPGP---YGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G G G G G KGD G PG GPKG G+QGI G GD G G +G G PGPP Sbjct: 1290 GMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPP 1349 Query: 349 GPY----GSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG 404 GPY G PG P G +G G +G G PGP GQ G G G+PG G+PG Sbjct: 1350 GPYDIIKGEPGLP-----GPEGPPGLKGLQGLPGP-----KGQQGVTGLVGIPGPPGIPG 1399 Query: 405 -EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIG-----SQGEQG 458 +G PG KGE G GPTGP+G G G G G GP G P + ++ Q Sbjct: 1400 FDGAPGQKGEMGPAGPTGPRG-----FPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQT 1454 Query: 459 IQGPIGPPG 467 I P P G Sbjct: 1455 IDDPQCPSG 1463 Score = 135 bits (341), Expect = 2e-31 Identities = 90/200 (45%), Positives = 104/200 (52%), Gaps = 36/200 (18%) Query: 592 GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPG 650 G G KG+RG PG+ G G PG+ QGP GP G PG KGD G PG+PG +G G Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGM--------QGPEGPQGPPGQKGDTGEPGLPGTKGTRG 94 Query: 651 PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPG---PPGPPGY 706 PPG G G + G G PG GPPGP G G GT+G +G G GLPG PGPPG Sbjct: 95 PPGASGYPG--NPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGL 152 Query: 707 -GSQGIKGE----------QGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIG 754 G +G GE +G +GFPG GT G GLPG +G G G G Sbjct: 153 PGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGP---------VGPPGFTG 203 Query: 755 EPGSPGKQGLQGPKGDLGLT 774 PG PG G G KG +GL+ Sbjct: 204 PPGPPGPPGPPGEKGQMGLS 223 Score = 77.4 bits (189), Expect = 7e-14 Identities = 42/95 (44%), Positives = 51/95 (53%), Gaps = 8/95 (8%) Query: 239 ICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERG 298 I + E G PG GPPG G G+ G +G +G G G GP GIPG+ G G++G Sbjct: 1354 IIKGEPGLPGPEGPPGLKGLQGLPGPKGQQG-----VTGLVGIPGPPGIPGFDGAPGQKG 1408 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP 333 E G G G +G P GP GP G+ G GPPG P Sbjct: 1409 EMGPAGPTGPRGFP---GPPGPDGLPGSMGPPGTP 1440 Score = 52.4 bits (124), Expect = 2e-06 Identities = 33/93 (35%), Positives = 47/93 (50%), Gaps = 5/93 (5%) Query: 710 GIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ 765 G+KG++G +G PG +G +G G G +G G++GD G+ G G G G PG G Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102 Query: 766 GPKGDLGLTKEEIIKLITEICGC-GPKCKETPL 797 G G G+ ++ I GC G K + PL Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPL 135 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 430 bits (1105), Expect = e-120 Identities = 270/652 (41%), Positives = 328/652 (50%), Gaps = 130/652 (19%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G PG PG PG G PG+KG +G G PG +G GE G G+PG +G G RG G G Sbjct: 759 GKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTG 818 Query: 305 IKGDKGSPGPYGPKGPRGIQG--ITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQ 362 KG +GSPG G GP G G ++GPPG G +G G +G PG GP G G PG Sbjct: 819 EKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSC 878 Query: 363 GIKGERGQEGRPGAPG--------PIGVGEPGQPGPRGPEGVPGERGLPGE-GFPGP--- 410 +G+ G PGAPG P G PG PGP GP GVPG +G+PG G PG Sbjct: 879 PSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGL 938 Query: 411 ----------------------------------KGEKGSEGPTGPQGL----------- 425 KGEKG +G G GL Sbjct: 939 TAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLE 998 Query: 426 -------QGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG---- 473 +G + +G+ G +G G GP G+PG G +G G++G GPPGP GP G Sbjct: 999 RPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGA 1058 Query: 474 ---QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGE---DGAAGKK 527 GLPG +GE G G TG +G G G G PG+ G PG PG+ GE G+AG+K Sbjct: 1059 VGSPGLPGLQGERGLTGLTGDKGEPG--PPGQPGYPGATGPPGLPGIKGERGYTGSAGEK 1116 Query: 528 GEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQRGLPGPEGP---------- 573 GE G PG+ G GPPG +G+ GP+G+ G+KG +G QGQ G PGP GP Sbjct: 1117 GEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSP 1176 Query: 574 --------KGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGL-SIRGPKGVQG 624 KG GI GP G+PG+ PGPPGP G +G G+ G G+ G +RG G G Sbjct: 1177 GPPGPQAEKGSEGIRGPSGLPGS--PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAG 1234 Query: 625 PRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP--------- 674 P G +G PG KG G+PG+PGP+G G PGP G G GA+GEPG GP Sbjct: 1235 PPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPG--STGRPGAEGEPGAMGPQGRPGPPGH 1292 Query: 675 ---------PGPSGPRGVGTQGPKGDTGQKGL---PGPPGPPGY-GSQGIKGEQGPQGFP 721 PGP+G VG +G +G TG++GL PG PGPPG+ G G G G G Sbjct: 1293 VGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKE 1352 Query: 722 GPKGTMG-HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 GP G G +G PG KG+ G G G+ G+KG G PG PGK G GP G G Sbjct: 1353 GPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPG 1404 Score = 401 bits (1031), Expect = e-111 Identities = 262/616 (42%), Positives = 300/616 (48%), Gaps = 112/616 (18%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE------R 297 +GDPG G PG G PG+ G+RG +G PG +G G GP G PG+ G G + Sbjct: 1011 EGDPGCVGSPGLPGPPGLPGQRGEEGPPG--MRGSPGPPGPIGPPGFPGAVGSPGLPGLQ 1068 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQG------NKGEPGPPGPY 351 GE G G+ GDKG PGP G G G TGPPG PG KG +G KGEPGPPG Sbjct: 1069 GERGLTGLTGDKGEPGP---PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSE 1125 Query: 352 GSPGAPGI----------GQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGP---R 391 G PG PG G G KG++G +G+PG PGP G VG PG PGP + Sbjct: 1126 GLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEK 1185 Query: 392 GPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPG 450 G EG+ G GLPG PGP G G +GP G GL G K G +GD GP GP G MG PG Sbjct: 1186 GSEGIRGPSGLPGS--PGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPG 1243 Query: 451 I-GSQGEQGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPG 507 G G G+ GP G G GP G G PG++GE G MGP G GP G +G GP G+PG Sbjct: 1244 FKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPG 1303 Query: 508 SIG-----------------LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK----GQ 546 G L G PG PG G G GE G GA G EGPPGK G Sbjct: 1304 PAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGP 1363 Query: 547 PGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP 606 PGPKGD G G KG G++G G G G+ G MGP G PPGP G+RG PG P Sbjct: 1364 PGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVG--------PPGPAGERGHPGAP 1415 Query: 607 GFKGEPGL-SIRGPKG------------------------------VQGPRGPVGAPGLK 635 G G PGL + G G +Q P APG Sbjct: 1416 GPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP 1475 Query: 636 GDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 G PG G G PG PG GL G +G G +G PGVRG PG G +G G G+ G Sbjct: 1476 GP--PGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGL 1533 Query: 695 KGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIG 754 G PGP GPPGYG G G G QG PG G PG G+ G+ G G + Sbjct: 1534 PGPPGPQGPPGYGKMGATGPMGQQGIPGIPGP-----PGPMGQPGKAGHCNPSDCFGAMP 1588 Query: 755 -EPGSPGKQGLQGPKG 769 E P + ++GP G Sbjct: 1589 MEQQYPPMKTMKGPFG 1604 Score = 383 bits (984), Expect = e-106 Identities = 285/749 (38%), Positives = 323/749 (43%), Gaps = 224/749 (29%) Query: 242 CEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERG-PGGIPGYKGDKGERG-- 298 C G G G PG G G+ GE GP G PG G G G PGG PG KGDKG G Sbjct: 426 CVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIP 485 Query: 299 -------ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKG-------------F 338 + GKPG+KG+KG P P P G Q G PG PGPKG Sbjct: 486 GKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGI 545 Query: 339 QGNKGEPGPP--------------------GPYGSPG--APGI-GQQGIKGERGQEGRPG 375 QG KGE G P G GSPG PG+ G+ G+ G +G++G G Sbjct: 546 QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFG 605 Query: 376 APGPIGVGEPGQPGPRGPEGVPGERGLPGE----------------GFPGPKGEKGSEGP 419 GP G PG PGP GP G+ G +G P E PGP GEKG GP Sbjct: 606 EAGP--AGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGP 663 Query: 420 TG-----PQGLQG-LSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP------- 465 G QG G +KG+KGD G G G G G G GE G+QGP GP Sbjct: 664 PGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDG 723 Query: 466 --------------------PGP---QGPAGQGLPGSKGEVGQMGPTGPRG--------- 493 PGP QGP G G PG G+ G G GP G Sbjct: 724 CTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPG 783 Query: 494 PVGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE------AGLPGARGPEGPPGKGQP 547 P G GVQGP+GEPG+ GLPG G+PG G G GE G+ GA GP GPPG Sbjct: 784 PPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPGASVS 843 Query: 548 GPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------------------------- 580 GP G +G++G G +G G GP G KGEPG Sbjct: 844 GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQP 903 Query: 581 GPFGMPGTSIPGPPGPKGDRGGPGIP---GFKGEPGL---------------SIRG---- 618 GP G PG IPGPPGP G G G+P G G+PGL SI G Sbjct: 904 GPQGPPG--IPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQ 961 Query: 619 ----------PKGVQGPRGPVGAPGL------------------KGDGYPGVPGPRGLPG 650 KG +G +G G PGL +GD G PG G PG Sbjct: 962 GQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPG 1021 Query: 651 PPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG----------------VGTQGPKGDTGQ 694 PGP GL G G +G PG+RG PGP GP G G +G G TG Sbjct: 1022 LPGPPGL--PGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGD 1079 Query: 695 KGLPGPPGPPGY-------GSQGIKGEQGPQGFPGPKGTMG----HGLPGQKGEHGERGD 743 KG PGPPG PGY G GIKGE+G G G KG G GLPG G G RG+ Sbjct: 1080 KGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGE 1139 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G +G+ GE G+ G G+ G GP G G Sbjct: 1140 RGPQGNSGEKGDQGFQGQPGFPGPPGPPG 1168 Score = 380 bits (977), Expect = e-105 Identities = 276/732 (37%), Positives = 320/732 (43%), Gaps = 219/732 (29%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPG---------NAQKGEAGERGPGGIPGYKGDK 294 +G PG G G G+PG+KG GP G PG + Q+G+ G RG G G +G+K Sbjct: 811 RGPPGPTGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEK 870 Query: 295 GERGECG------------------------KPGIKGDKGSPGPYGPKGPRGIQGITGP- 329 GE GEC +PG +G G PGP GP G G+QG+ G Sbjct: 871 GEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNN 930 Query: 330 --PGDP-------------------------------------GPKGFQGNKGEPG---- 346 PG P G KG QG G PG Sbjct: 931 GLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNC 990 Query: 347 ----------------------PPGPYGSPGAPGI----GQQGIKGERGQEGRPGAPGPI 380 PG GSPG PG GQ+G +G G G PG PGPI Sbjct: 991 AQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPI 1050 Query: 381 GV-GEPGQPGPRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKG 435 G G PG G G G+ GERGL G +G PGP G+ G G TGP GL G IKGE+G Sbjct: 1051 GPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPG--IKGERG 1108 Query: 436 DIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGP 494 G G +G G PG +G+ GP GP GP+G G QG G KG+ G G G GP Sbjct: 1109 YTGSAGEKGEPGPPG-----SEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGP 1163 Query: 495 VGIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEG 554 GP G PG +G PG PG E G+ G +G +GLPG+ GP GPPG GP G +G Sbjct: 1164 -----PGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGI--QGPAGLDG 1216 Query: 555 KKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG 613 G G G RG PGP GP PG+MGP G G T PG PGPKGD G PG PG G PG Sbjct: 1217 LDGKDGKPGLRGDPGPAGP---PGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPG 1273 Query: 614 LS----IRGPKGVQGPRGPVGAPG--------------LKGD----------GYPGVPGP 645 GP+G GP G VG PG LKGD G PG PGP Sbjct: 1274 AEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGP 1333 Query: 646 RGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSG-PRGVGTQGPKGDTGQKGLPGPPGP 703 G PGPPG G G G G G+ G GPPGP G P G +G G+ G+ G+PG PG Sbjct: 1334 PGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGK 1393 Query: 704 PG----YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEH-------------------- 738 G G G GE+G G PGP G+ G G+PG G+ Sbjct: 1394 SGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDE 1453 Query: 739 -------------------GERGDVGKKGDKGEIGEPGSPG---------KQGL------ 764 G G GK G G G PGSPG +QGL Sbjct: 1454 RMAYYTSRMQFPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGL 1513 Query: 765 ---QGPKGDLGL 773 +G KGD+G+ Sbjct: 1514 PGTKGEKGDIGI 1525 Score = 370 bits (949), Expect = e-102 Identities = 259/621 (41%), Positives = 306/621 (49%), Gaps = 118/621 (19%) Query: 244 KGDPGDPGPPGTHGNPGIKGE--------------RGPKGNPGNAQKGEAGERGPGGIPG 289 KG+ G PGPPG+ G G +G GPKG +KGE+G GP G+PG Sbjct: 339 KGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKG-----EKGESGALGPSGLPG 393 Query: 290 YKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPG 349 G+KG++GE G GIKG G PG G G + G G GDPG G +G GEPGPPG Sbjct: 394 STGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPG 453 Query: 350 -----PYGSPGAPGI--GQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRG---------- 392 G PG PG G G KG++G G PG GP G+PG+PG +G Sbjct: 454 LPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPGKEGP--GGKPGKPGVKGEKGDPCEVCP 511 Query: 393 --PEGVPGERGLPGEGFPGPKGEKGSEGPT-GPQGLQGLSIKGEKGD------------- 436 PEG GLPG+ PGPKGE G P G G+QG IKGEKG+ Sbjct: 512 TLPEGFQNFVGLPGK--PGPKGEPGDPVPARGDPGIQG--IKGEKGEPCLSCSSVVGAQH 567 Query: 437 -IGPVGPQGPMGIPGI---------------GSQGEQGIQGPIGPPGPQGPAG-QGLPGS 479 + G G +G PG G +G G GP G PGP GP G G+ G+ Sbjct: 568 LVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGA 627 Query: 480 KGEVGQMGPTGPR---GPVGI----GVQGPKGEPG--SIGLPGQPGVPGEDGAAGKKGEA 530 KGE + P G V + G G KGEPG GLPG+ G GE G G+KG+A Sbjct: 628 KGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDA 687 Query: 531 GLPGARGPEGPPGK----GQPGPKGDEGKKGSKGN--------QG----QRGLPGPEGPK 574 G PG G G G+ G+PG +G G KG KG+ QG G PG GPK Sbjct: 688 GNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPK 747 Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGL 634 GE G G G PG PG PG G +G PG+ G +GEPG R GVQGP+G GAPGL Sbjct: 748 GEQGPEG-VGRPGK--PGQPGLPGVQGPPGLKGVQGEPGPPGR---GVQGPQGEPGAPGL 801 Query: 635 KGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 G G+PGPRG PGP G+ GA+G PGV+G GP GP G GP G GQ Sbjct: 802 --PGIQGLPGPRGPPGP--------TGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQ 851 Query: 695 KGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKG-EHGERGDVGKKGDKGE 752 +G G G PG G +G KGE G P + G+PG G G G +G G Sbjct: 852 QGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911 Query: 753 IGEPGSPGKQGLQGPKGDLGL 773 G PG PG GLQG G+ GL Sbjct: 912 PGPPGPPGVPGLQGVPGNNGL 932 Score = 307 bits (786), Expect = 4e-83 Identities = 242/635 (38%), Positives = 283/635 (44%), Gaps = 164/635 (25%) Query: 287 IPGYKGDKGERG----------ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK 336 + G K ERG EC P + G + S P GP+G +G G PG PG Sbjct: 293 LTGRISQKAERGAKVHQETAADEC-PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGS- 350 Query: 337 GFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPG-PIGVGEPGQPGPRGPEG 395 +G KG G SP AP +G KGE+G+ G G G P GE GQ G +G G Sbjct: 351 --KGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGG 408 Query: 396 VPGERGLPG-EGFP------GPKGEKGSEGPTGPQGL------------QGLSIKGEKGD 436 + G G PG +G P GPKG+KG G GP+GL G+ + G GD Sbjct: 409 IKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGD 468 Query: 437 IGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-------------------GLP 477 P GP GP G GS G G +GP G PG G G+ GLP Sbjct: 469 --PGGPPGPKG--DKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLP 524 Query: 478 GSKGEVGQMG-PTGPRGPVGI-GVQGPKGEP--------------------GSIGLP--G 513 G G G+ G P RG GI G++G KGEP G +G P G Sbjct: 525 GKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFG 584 Query: 514 QPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQR-------- 565 PG+PG G G KGE G G GP G P G PGP G G KG+KG + Sbjct: 585 LPGLPGRAGVPGLKGEKGNFGEAGPAGSP--GPPGPVGPAGIKGAKGEPCEPCPALSNLQ 642 Query: 566 -------GLPGPEGPKGEPGIMGPFGMPG-------TSIPGPPGPKGDRGGPGIPGFKGE 611 LPGP G KGEPG G FG+PG + G G G+ G PG PG G Sbjct: 643 DGDVRVVALPGPSGEKGEPGPPG-FGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGR 701 Query: 612 PGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVP----------GPRGLPGPPGPMGLRGVG 661 PGLS G GVQGP GP G KGDG P G G PGP G G GVG Sbjct: 702 PGLS--GEPGVQGPAGPKGE---KGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVG 756 Query: 662 DTGAKGE---PGVRGPP------GPSGPRGVGTQGPKGDTGQ------KGLPGPPGPPG- 705 G G+ PGV+GPP G GP G G QGP+G+ G +GLPGP GPPG Sbjct: 757 RPGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGP 816 Query: 706 ------YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGS- 758 GS G+KG GP G PG + G GQ+G+ G RG G+KG +GE GEPG Sbjct: 817 TGEKGAQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGEC 876 Query: 759 -------------PGKQGL-------QGPKGDLGL 773 PG GL GP+G G+ Sbjct: 877 SCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGI 911 Score = 291 bits (746), Expect = 2e-78 Identities = 194/492 (39%), Positives = 227/492 (46%), Gaps = 111/492 (22%) Query: 243 EKGDPGDPGP---PGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 EKG+PG PG PG G G +GERGP+GN G +KG+ G +G G PG G G G+ Sbjct: 1115 EKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSG--EKGDQGFQGQPGFPGPPGPPGFPGK 1172 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP---GPKGFQGNKGEPGPPGPYGSPGA 356 G PG G + G G +GP G+ G GPPG P GP G G G+ G PG G PG Sbjct: 1173 VGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGP 1232 Query: 357 PG-IGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG----EGFPGPK 411 G G G G +G+ G PG PGP G+ G+PGP G G PG G PG +G PGP Sbjct: 1233 AGPPGLMGPPGFKGKTGHPGLPGP--KGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPP 1290 Query: 412 GEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG--------------------- 450 G G GP G G G+S G KGD G G +G G+PG Sbjct: 1291 GHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAG 1350 Query: 451 -IGSQGEQGIQGPIGPPGPQGPAGQ----------GLPGSKGEVGQMGPTGPRGPVGIGV 499 G G+QG GP GP G G AGQ G+PG G+ G MGP GP GP G Sbjct: 1351 KEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPA--GE 1408 Query: 500 QGPKGEPGSIGLPGQPGVPGEDG------------------------------------A 523 +G G PG G PG PGVPG G Sbjct: 1409 RGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEM 1468 Query: 524 AGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGP 582 A G G PG G G PG G PG G G++G +G G RGLPG +G KG+ GI Sbjct: 1469 AAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI--- 1525 Query: 583 FGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPG 641 G+ G +PGPPGP+G PG+ G G GP G G PG+ PG Sbjct: 1526 -GIAGENGLPGPPGPQGP------PGY---------GKMGATGPMGQQGIPGI-----PG 1564 Query: 642 VPGPRGLPGPPG 653 PGP G PG G Sbjct: 1565 PPGPMGQPGKAG 1576 Score = 152 bits (383), Expect = 2e-36 Identities = 105/262 (40%), Positives = 128/262 (48%), Gaps = 51/262 (19%) Query: 537 GPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLP--------GPEGPKGEPGIMGPFGMPG 587 GP+G G +G PGP G +G+KG++GN R P GP+G KGE G +GP G+ Sbjct: 334 GPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGL-- 391 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRG 647 PG G KG +G G G KG PG G G G +G G KGD PG GP G Sbjct: 392 ---PGSTGEKGQKGEKGDGGIKGVPGKP--GRDGRPGEICVIGPKGQKGD--PGFVGPEG 444 Query: 648 LPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY- 706 L G PGP GL G G G PG P GP GPKGD G G+PG GP G Sbjct: 445 LAGEPGPPGLPGPPGIGLPGTPG-----DPGGP-----PGPKGDKGSSGIPGKEGPGGKP 494 Query: 707 GSQGIKGEQG---------PQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPG 757 G G+KGE+G P+GF G LPG+ G GE GD + G Sbjct: 495 GKPGVKGEKGDPCEVCPTLPEGFQNFVG-----LPGKPGPKGEPGD--------PVPARG 541 Query: 758 SPGKQGLQGPKGDLGLTKEEII 779 PG QG++G KG+ L+ ++ Sbjct: 542 DPGIQGIKGEKGEPCLSCSSVV 563 Score = 109 bits (273), Expect = 1e-23 Identities = 71/201 (35%), Positives = 90/201 (44%), Gaps = 29/201 (14%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGE-------------------RG 283 E+G PG PGP G+ G PG+ G G N ++ E Sbjct: 1408 ERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPME 1467 Query: 284 PGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPK-----GF 338 PG G G+ G G+PG G G PG G +G +G+ G+ G PG G K G Sbjct: 1468 MAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGI 1527 Query: 339 QGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVP 397 G G PGPPGP G PG G+ G G GQ+G PG PGP G +G+PG+ G P Sbjct: 1528 AGENGLPGPPGP---QGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCF 1584 Query: 398 GERGLPGEGFPGPKGEKGSEG 418 G + + +P K KG G Sbjct: 1585 GAMPME-QQYPPMKTMKGPFG 1604 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 426 bits (1096), Expect = e-119 Identities = 265/594 (44%), Positives = 320/594 (53%), Gaps = 69/594 (11%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGE 299 +G PGD GPPG +G G+KG+ G +G PG +G+ G GP G PG +G G +G Sbjct: 909 EGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGF 968 Query: 300 CGKPGIKG------DKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGS 353 G+PG+ G D G PGP G +G G G+ G PG G KG +G G PG PGP GS Sbjct: 969 PGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGS 1028 Query: 354 PGAPGI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGP 410 G PG+ G G GE G +G PG+ GP G+ G G+ GPRGP+G GE+G G +G PGP Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088 Query: 411 KGEKGSEGPTGPQGLQG-LSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQ 469 +G G G G G +G L +G G GP GP G G+PG G QG QGPIGPPG Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPG--EPGPQGPQGPIGPPGEM 1146 Query: 470 GPAGQ-------GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPGQP 515 GP G GLPG G G +GP G G G+ G++G G G GL G Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206 Query: 516 GVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPK 574 G PG DG G+KG+ GL G GP GPPG G GP+G GK+G KG G +G G +G Sbjct: 1207 GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQL 1266 Query: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPG---FKGEPGLS-IRGPKGVQGPRGPVG 630 GE G+ G G PGT PGP G +G G G PG +GEPGL+ G KG+ GP GP G Sbjct: 1267 GEMGVPGDPGPPGT--PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPG 1324 Query: 631 APGLKGDGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGV----GT 685 G KG+ G G GPPGP G RG VGD G +GEPG G PG G +G+ G Sbjct: 1325 PKGEKGE--QGEDGKA--EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQ 1380 Query: 686 QGPKGDTGQKGLPGPPGPPGY----------GSQGIKGEQGPQGFPGPKGTMGH------ 729 QG G G +G PGP G G G+ G +G QG QG PGP+G +G Sbjct: 1381 QGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGI 1440 Query: 730 ----GLPG---QKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 GLPG Q G+ GE+GD G G G G+ G+PG GL G +G G E Sbjct: 1441 AGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGE 1494 Score = 424 bits (1091), Expect = e-118 Identities = 270/592 (45%), Positives = 316/592 (53%), Gaps = 75/592 (12%) Query: 248 GDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKG 307 G+ GPPG GNPG G GP G PG G+ G GP G PG KG KG G G+PG+KG Sbjct: 796 GERGPPGLDGNPGELGLPGPPGVPGLI--GDLGVLGPIGYPGPKGMKGLMGSVGEPGLKG 853 Query: 308 DKGS---------PGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGE---PGPPGPYGSPG 355 DKG PG G KG +G+ G G G PGP G G+KG PGPPGP G PG Sbjct: 854 DKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPG 913 Query: 356 APGIGQQGIKGERGQEGRPGA---PGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGP 410 IG G G G +G+PGA PGP G +G G GP GP G PG G PG +GFPG Sbjct: 914 --DIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGR 971 Query: 411 ------KGEKGSEGPTGPQGLQG----LSIKGEKGDIGPVGPQGPMGIPGI----GSQGE 456 KGE G G GP G QG + + GE G +G G +G MG PG+ GS G Sbjct: 972 PGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGH 1031 Query: 457 QGIQGPIGPPG---PQGPAG-QGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGL 511 G+ G +G PG PQGP G +G PG +G G+ GP GP GP G G +G KG PG G Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGR 1091 Query: 512 PGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGPKGDEGKKGSKGNQGQRGLPGP 570 PG+PG G G G G G PG GP GPPG KG PG G +G +G G G+ G GP Sbjct: 1092 PGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGP 1151 Query: 571 EGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPV 629 G GEPG+ G GM G P G PG +G G G PG +G+ G GP G++G RG Sbjct: 1152 PGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM--GPDGLKGDRGDP 1209 Query: 630 GAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGV----------GDTGAKGE---------- 668 G G G+ G G+ G G PGPPG G+RG G TGAKG Sbjct: 1210 GPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEM 1269 Query: 669 --PGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725 PG GPPG GP+G G+ GP G G+ G G PG GY G KG GP G PGPKG Sbjct: 1270 GVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGY--DGHKGIVGPLGPPGPKG 1327 Query: 726 TMGHG-----LPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G G G+RG VG +GD+GE G+PG PG++G+QG +G G Sbjct: 1328 EKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPG 1379 Score = 422 bits (1085), Expect = e-118 Identities = 268/611 (43%), Positives = 314/611 (51%), Gaps = 90/611 (14%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGE--- 299 KG+PGDPG PG G G G G G PG +KG+ G GP G+PG KG G G Sbjct: 978 KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI 359 G PG G +G PG GP G RG +G GP G GP G QG++G GPPGP G PG PG Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPG- 1096 Query: 360 GQQGIKGERGQ---EGRPGAPGPIGV-------GEPGQPGPRGPEGVPGERGLPGE---- 405 QQG+ GERG G PG PGP G GEPG GP+GP G PGE G G Sbjct: 1097 -QQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAV 1155 Query: 406 ---GFPGPKGEKGSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI---- 451 G PG G KG GP G G QGL ++G+ G +GP G +G G PG Sbjct: 1156 GEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEH 1215 Query: 452 GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIG 510 G +G++G+ G GPPGP G G +G G G+ G+ G TG +G G QG GE G G Sbjct: 1216 GEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY--QGQLGEMGVPG 1273 Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-------KGQPGPKGDEGKKGSKGNQG 563 PG PG PG G+ G G G PG G +G PG KG GP G G KG KG QG Sbjct: 1274 DPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG 1333 Query: 564 Q----RGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP 619 + G PGP G +G G G G PG PG PG +G +G G PG +G+PG GP Sbjct: 1334 EDGKAEGPPGPPGDRGPVGDRGDRGEPGD--PGYPGQEGVQGLRGKPGQQGQPGHP--GP 1389 Query: 620 KGVQGPRGPVGAPGLKGD-------GYPGVPGPRGLPGPPGPMGLRGV------------ 660 +G GP+G GA G KG G GV G +GLPGP G +G +G+ Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGR 1449 Query: 661 -GDTGAKGEPGVRGPPGPSGPRGV----------GTQGPKGDTGQKGLPGPPGPPGY--- 706 G G +GE G G PGP GP G G QGP G G+ GLPG GPPG Sbjct: 1450 DGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGT 1509 Query: 707 ----GSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGK 761 G G +GE G +G PG G MG G+ G G G GD+G KG +G G PG GK Sbjct: 1510 EGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGK 1569 Query: 762 QGLQGPKGDLG 772 +G+ GP G LG Sbjct: 1570 EGIVGPLGILG 1580 Score = 421 bits (1082), Expect = e-117 Identities = 264/580 (45%), Positives = 314/580 (54%), Gaps = 76/580 (13%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKP 303 KGD G PGPPG G PGI G RGP+G PG P G PG G G +G+ G P Sbjct: 630 KGDCGLPGPPGLPGLPGIPGARGPRGPPG-----------PYGNPGLPGPPGAKGQKGDP 678 Query: 304 GIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGPPGPYGSPGAPGI- 359 G+ K G G G G+ G GPPG G KG+ G+ GE G PGP GSPGA G Sbjct: 679 GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYP 738 Query: 360 GQQGIKGERGQEGRPGAPGPIGV----GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEK 414 G+QG+ G G G G+ G IG+ G PG G RG GVPG+RG G GFPG GE+ Sbjct: 739 GRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGER 798 Query: 415 GSEGPTGPQGLQGL-------SIKGEKGDIGPVGPQGPMGIPGI----------GSQGEQ 457 G G G G GL + G+ G +GP+G GP G+ G+ G +GEQ Sbjct: 799 GPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQ 858 Query: 458 GIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQP 515 G+ G G PG QG G QGLPG G G+ GP G G G IG GP PG G PG Sbjct: 859 GVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGP---PGPEGFPGDI 915 Query: 516 GVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 G PG++G G KG+ PGARG GP +GQ GP+GDEG G G G G PG +G G Sbjct: 916 GPPGDNGPEGMKGK---PGARGLPGP--RGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPG 970 Query: 576 EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLK 635 PG+ G G PG PG PGP G++G G G GEPG I G KG +G GP G PG K Sbjct: 971 RPGLDGVKGEPGD--PGRPGPVGEQGFMGFIGLVGEPG--IVGEKGDRGMMGPPGVPGPK 1026 Query: 636 GD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 G G+PG+PG G PG PGP G G++G PG+RG G GPR G GP G+ G Sbjct: 1027 GSMGHPGMPGGMGTPGEPGPQ-----GPPGSRGPPGMRGAKGRRGPR--GPDGPAGEQGS 1079 Query: 695 KGLPGPPGPPGY----GSQGIKGEQGP------QGFPGPKGTMG-HGLPGQKGEHGER-- 741 +GL GPPGP G G QG+ GE+G G PGP G G GLPG+ G G + Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139 Query: 742 ----GDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 G++G KG G +GEPG PG+ G++G G LG E+ Sbjct: 1140 IGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQ 1179 Score = 415 bits (1066), Expect = e-115 Identities = 254/583 (43%), Positives = 301/583 (51%), Gaps = 66/583 (11%) Query: 245 GDPGDPGPPGTHG------------NPGIKGERGPKGNPGN----AQKGEAGERGPGGIP 288 G+PG PGPPG G + G KG+ G G GN +KG G GP G P Sbjct: 661 GNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP 720 Query: 289 GYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G +G G G G G G +G PGP G GP+G +G G PG G G G +G PG P Sbjct: 721 GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVP 780 Query: 349 GPYGSPGAPGI----------GQQGIKGERGQEGRPGAPGPIG----VGEPGQPGPRGPE 394 G G G PG G G GE G G PG PG IG +G G PGP+G + Sbjct: 781 GKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMK 840 Query: 395 GVPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPM 446 G+ G G PG +G PG G+ G +G G QGL G +G+ G +G VG +G + Sbjct: 841 GLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSI 900 Query: 447 GIPGIGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE 505 G P G G +G G IGPPG GP G +G PG++G G G GP G G GP G Sbjct: 901 GFP--GPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDE--GPMGPPGA 956 Query: 506 PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGN 561 PG G PG+ G PG G G KGE G PG GP G G G G G G+KG +G Sbjct: 957 PGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGM 1016 Query: 562 QGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG 621 G G+PGP+G G PG+ G G PG PGP GP G RG PG+ G KG RGP+G Sbjct: 1017 MGPPGVPGPKGSMGHPGMPGGMGTPGE--PGPQGPPGSRGPPGMRGAKGR-----RGPRG 1069 Query: 622 VQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGP 680 GP G G+ GLKG PGP+G PG PG G+ G G G++G PG+ GP GP G Sbjct: 1070 PDGPAGEQGSRGLKGP-----PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGT 1124 Query: 681 RGV----GTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGEQGPQGFPGPKGTMG-HGLPGQ 734 +G+ G QGP+G G G GP GPPG G G+ GE G +G GP GT G GL GQ Sbjct: 1125 KGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQ 1184 Query: 735 KGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 +GE G GD G G G G+ G PG G G KG GL E+ Sbjct: 1185 RGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGED 1227 Score = 320 bits (821), Expect = 4e-87 Identities = 204/463 (44%), Positives = 239/463 (51%), Gaps = 79/463 (17%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECG 301 E G GD GP G G G +G+ GP G G Q+G GE GP G PG G +G G+ G Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSG 1246 Query: 302 KPGIKGD---KGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG 358 K G KG KG+ G G G G+ G GPPG PGPKG +G+ G G PG G+ G PG Sbjct: 1247 KQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPG 1306 Query: 359 I----------------GQQGIKGERGQEGR-------PGAPGPIG----VGEPGQPGPR 391 + G +G KGE+G++G+ PG GP+G GEPG PG Sbjct: 1307 LAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYP 1366 Query: 392 GPEGVPGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVG 441 G EGV G RG PG+ G+PGPKG KG+EGP G QG G G +G G G Sbjct: 1367 GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAG--APGRRGVQGLQG 1424 Query: 442 PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQG 501 GP G+ +G QG +GI GP G PG G AGQ +GE G G GP GP G Sbjct: 1425 LPGPRGV--VGRQGLEGIAGPDGLPGRDGQAGQ-----QGEQGDDGDPGPMGPA-----G 1472 Query: 502 PKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEG----PPGKGQPGPKGDEGKKG 557 +G PG GLPG G PG G +G G+ G PG RG EG P +G+PG KG G G Sbjct: 1473 KRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSG 1532 Query: 558 SKGNQGQRGLPGPEGPKGE---PGIMGPFGMPG-TSIPGPPGPKGDRGGPGIPGFKGEPG 613 G G GL GP+GP G+ GI GP G PG G GP G G G+PG KG+ G Sbjct: 1533 EMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKG 1592 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMG 656 RG G+QGPRGP PGPRG PGPPGP G Sbjct: 1593 --SRGDWGLQGPRGP--------------PGPRGRPGPPGPPG 1619 Score = 205 bits (521), Expect = 2e-52 Identities = 124/285 (43%), Positives = 158/285 (55%), Gaps = 28/285 (9%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 ++G+PGDPG PG G G++G+ G +G PG+ G G GP G G +G KG++G+ G Sbjct: 1356 DRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHP--GPRGWPGPKGSKGAEGPKGKQGKAGA 1413 Query: 303 PG---IKGDKGSPGPYGPKGPRGIQGITGPPGDPG------PKGFQGNKGEPGPPGPYGS 353 PG ++G +G PGP G G +G++GI GP G PG +G QG+ G+PGP GP G Sbjct: 1414 PGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGK 1473 Query: 354 PGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPG-EGFPGPKG 412 G PG+ G G +G PG G G+ PGQ GP G G G GLPG +G PG KG Sbjct: 1474 RGNPGVA-----GLPGAQGPPGFKGESGL--PGQLGPPGKRGTEGRTGLPGNQGEPGSKG 1526 Query: 413 EKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPGI----GSQGEQGIQGPIGPPG 467 + G G G G+ GL KG GDIG G QGP G PG+ G G GI GP G PG Sbjct: 1527 QPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPG 1586 Query: 468 PQGPAGQ----GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGS 508 P+G G GL G +G G G GP GP G +Q + + G+ Sbjct: 1587 PKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA 1631 Score = 185 bits (469), Expect = 2e-46 Identities = 113/255 (44%), Positives = 138/255 (54%), Gaps = 34/255 (13%) Query: 238 KICECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGER 297 K E KG G G PG G G++G GP+G G ++G G GP G+PG G G++ Sbjct: 1399 KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG--RQGLEGIAGPDGLPGRDGQAGQQ 1456 Query: 298 GECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAP 357 GE +GD G PGP GP G RG G+ G PG GP GF+G G PG GP Sbjct: 1457 GE------QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGP------- 1503 Query: 358 GIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG-EGFPGPKGEKG 415 G+RG EGR G PG G G GQPG G G PG GL G +G PG G KG Sbjct: 1504 -------PGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKG 1556 Query: 416 SEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQGPIGPPGPQG- 470 +GP GP GL G++G +GP+G GP G+PG GS+G+ G+QGP GPPGP+G Sbjct: 1557 IQGPRGPPGLM-----GKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGR 1611 Query: 471 PAGQGLPGSKGEVGQ 485 P G PG ++ Q Sbjct: 1612 PGPPGPPGGPIQLQQ 1626 Score = 98.6 bits (244), Expect = 3e-20 Identities = 90/266 (33%), Positives = 99/266 (37%), Gaps = 71/266 (26%) Query: 573 PKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIP-------GFK---GEPGLSIRGPKGV 622 P PG P T +P G R P +P G K G GPK Sbjct: 491 PAPTPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPK-- 548 Query: 623 QGPRGPV--------------------------------------------GAPGLKGDG 638 PR PV +P G Sbjct: 549 SSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSG 608 Query: 639 YP------GVPGP--RGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRG-VGTQGP 688 Y P P G PGP G GL G G G G PG RGP GP GP G G GP Sbjct: 609 YSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGP 668 Query: 689 KGDTGQKGLPG-PPGPPGYGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGK 746 G GQKG PG PG G++G G G G PGP G GH G PG G GE+ G+ Sbjct: 669 PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQ---GQ 725 Query: 747 KGDKGEIGEPGSPGKQGLQGPKGDLG 772 G +G G G PG+QGL GP GD G Sbjct: 726 PGPEGSPGAKGYPGRQGLPGPVGDPG 751 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 424 bits (1090), Expect = e-118 Identities = 269/617 (43%), Positives = 305/617 (49%), Gaps = 93/617 (15%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G G G PG G PG G G +G PGN G G +GP G PG GDKG G G G Sbjct: 463 GKEGPVGLPGIDGRPGPIGPAGARGEPGNI--GFPGPKGPTGDPGKNGDKGHAGLAGARG 520 Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI----- 359 G G+ G GP GP+G+QG G G PGP GFQG G GP G G PG G+ Sbjct: 521 APGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFG 580 Query: 360 --GQQGIKGERGQEGRPGAPGPIG----------------------VGEPGQPGPRGPEG 395 G G +GERG G GA GP G VG G GP GP G Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640 Query: 396 VPGERGLPG-------EGFPGPKGEKGSEGPTGPQGLQG----------LSIKGEKGDIG 438 +PGERG G +G PG +GE G+ G G +G G +GE G G Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAG 700 Query: 439 PVGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGEVGQMGPTGP 491 P GP GP G P G +GE G GP G GP G AGQ G G KGE G +GPTGP Sbjct: 701 PAGPAGPRGSP--GERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGP 758 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQ 546 G G G GP G GS G G PG+ G GAAG+ G G G GP GPPG +G Sbjct: 759 VGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGL 818 Query: 547 PGPKGDEGKKGSKGNQGQRGLP---GPEGPKGEPGIMGPFGMPG-------TSIPGPPGP 596 GP+GD+G G G G G P G +GP GE G GP G PG I G PG Sbjct: 819 RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS 878 Query: 597 KGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGL 648 +G+RG PG+ G GEPG L I GP G +GP G VG+PG+ G DG PG GP G Sbjct: 879 RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938 Query: 649 PGPPGPMGLRG----VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGP 700 G PG G RG +G GA G PG GP GP+G G G GP G G G GP Sbjct: 939 DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGP 998 Query: 701 PGPPGY-GSQGIKGEQGPQGFPGPKGTMG-HGLPGQKGEHGER---GDVGKKGDKGEIGE 755 GP G G +G GE+GP+G PG KG G GLPG G HG++ G VG G +G G Sbjct: 999 SGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGP 1058 Query: 756 PGSPGKQGLQGPKGDLG 772 G GK G G G +G Sbjct: 1059 SGPAGKDGRTGHPGTVG 1075 Score = 423 bits (1088), Expect = e-118 Identities = 268/615 (43%), Positives = 310/615 (50%), Gaps = 89/615 (14%) Query: 245 GDPGDPGPPGTHGNPG---IKGERGPKGNPG-NAQKGEAGERGPGGIPGYKGDKGERGEC 300 G PG GP G G PG G +GP G+PG N KG AG G G PG G+ G +G Sbjct: 475 GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGD---PGPKGFQGNKGEPGPPGPYGSPGAP 357 G G++G KG GP GP G +G+ G +GP G+ PG +G G G PGP GP G G P Sbjct: 535 GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPP 594 Query: 358 G-IGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG----- 404 G G G G G G G PGP G VG G GP GP G+PGERG G Sbjct: 595 GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGK 654 Query: 405 --EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKGDIGPVGPQGPMGIPGIG 452 +G PG +GE G+ G G +G G +GE G GP GP GP G PG Sbjct: 655 GEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG-- 712 Query: 453 SQGEQGIQGPIGPPGPQGPAGQ-------GLPGSKGEVGQMGPTGPRGPVG-IGVQGPKG 504 +GE G GP G GP G AGQ G G KGE G +GPTGP G G G GP G Sbjct: 713 ERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772 Query: 505 EPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKG 560 GS G G PG+ G GAAG+ G G G GP GPPG +G GP+GD+G G G Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832 Query: 561 NQGQRGLPG---PEGPKGEPGIMGPFGMPGTS-------IPGPPGPKGDRGGPGIPGFKG 610 G G PG +GP GE G GP G PG I G PG +G+RG PG+ G G Sbjct: 833 EVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG 892 Query: 611 EPG-LSIRGPKGVQGPRGPVGAPGLKG-------DGYPGVPGPRGLPGPPGPMGLRG--- 659 EPG L I GP G +GP G VG+PG+ G DG PG GP G G PG G RG Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952 Query: 660 -VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKG 713 +G GA G PG GP GP+G G G GP G G G GP GP G G +G G Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012 Query: 714 EQGPQGFPGPKGTMG-HGLPGQKGEHGERGDVGK---------------KGDKGEIGEPG 757 E+GP+G PG KG G GLPG G HG++G G G G G PG Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072 Query: 758 SPGKQGLQGPKGDLG 772 + G G++GP+G G Sbjct: 1073 TVGPAGIRGPQGHQG 1087 Score = 423 bits (1087), Expect = e-118 Identities = 263/589 (44%), Positives = 307/589 (52%), Gaps = 68/589 (11%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPG 304 G+PG G G GN G G GP+G PG + GE G+RGP G G G G G G PG Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPS--GEEGKRGPNGEAGSAGPPGPPGLRGSPG 403 Query: 305 IKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IG 360 +G G+ G G GP G +G +GP G GP G G GEPG GP G PG+PG G Sbjct: 404 SRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAG 463 Query: 361 QQGIKGERGQEGRPGAPGPIGV-GEPGQ---PGPRGPEGVPGERGLPGE-------GFPG 409 ++G G G +GRPG GP G GEPG PGP+GP G PG+ G G G PG Sbjct: 464 KEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPG 523 Query: 410 PKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGEQGIQGP 462 P G G++GP GPQG+QG KG+ GP GP G G+PG +G GE+G+ G Sbjct: 524 PDGNNGAQGPPGPQGVQG-----GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE 578 Query: 463 IGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGE 520 G PGP GP G+ G PG G G GP G RGP G G G KGEPG +G G G G Sbjct: 579 FGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGP 638 Query: 521 DGAAGKKGEAGLPGARGPEGPPG-------------KGQPGPKGDEGKKGSKGNQGQRGL 567 G G++G AG+PG +G +G PG +G PG G G G+ G++G+ G Sbjct: 639 SGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGA 698 Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKG---VQG 624 GP GP G G G G G + GP G G G G PG KGE G +GPKG V G Sbjct: 699 AGPAGPAGPRGSPGERGEVGPA--GPNGFAGPAGAAGQPGAKGERGA--KGPKGENGVVG 754 Query: 625 PRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPGVRGPPGPSGPRG 682 P GPVGA G G +G PG G RG GPPG G G G TG G G+ GPPGP GP G Sbjct: 755 PTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAG 814 Query: 683 V-------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPGPKGTMGH----G 730 G QGP G TG+ G GPPG G G G G GP G PGP+G +G G Sbjct: 815 KEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG 874 Query: 731 LPGQKGEHG---ERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 LPG +GE G G VG+ G G G PG+ G G G G G E Sbjct: 875 LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGE 923 Score = 417 bits (1073), Expect = e-116 Identities = 269/604 (44%), Positives = 307/604 (50%), Gaps = 88/604 (14%) Query: 248 GDPGPPGTHGNPGIKGERGPKGNPGN-AQKGEAGERGPGGIPGYKGDKGERGECGKPGIK 306 G GPPG G PG +G +GP G PG Q G AG RGP G PG GE G GKPG Sbjct: 97 GPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG---KAGEDGHPGKPGRP 153 Query: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG----IGQQ 362 G++G GP G +G G G+ G G G G G KG+PG PG G PGAPG GQ Sbjct: 154 GERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQT 213 Query: 363 GIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-EGFPGPKGE---KGSE 417 G +G G+ GR GAPGP G G G GP GP G G G PG G PGPKGE G+ Sbjct: 214 GARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA 273 Query: 418 GPTGPQGLQG-LSIKGEKGDIGPVGP------------------------QGPMGIPG-I 451 GP GP G +G + + G G +GP G GP GIPG + Sbjct: 274 GPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV 333 Query: 452 GSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIG 510 G+ G G +G +G PGP G G+ G+KGE G GP GP GP G G +GP GE GS G Sbjct: 334 GAAGATGARGLVGEPGPAGSKGES--GNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391 Query: 511 LPGQPGV---PGEDGAAGKKGEAGL---PGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQ 564 PG PG+ PG G G G AG+ PG+RG GP G GP GD G+ G G G Sbjct: 392 PPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP--AGVRGPNGDAGRPGEPGLMGP 449 Query: 565 RGLPGPEGPKGEPGIMGPFGMPG-TSIPGP---------------PGPKGDRGGPGIPGF 608 RGLPG G G G GP G+PG PGP PGPKG G PG G Sbjct: 450 RGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGD 509 Query: 609 KGEPGLS-------IRGPKGVQGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRG- 659 KG GL+ G G QGP GP G G KG+ G PG PG +GLPGP GP G G Sbjct: 510 KGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGK 569 Query: 660 VGDTGAKGEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPG-------YGS 708 G+ G GE G+ GP GP G RG G GP G G +G GPPGP G G+ Sbjct: 570 PGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGA 629 Query: 709 QGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768 G G GP G PG +G G+PG KGE GE G G+ G+ G G G+PG G GP Sbjct: 630 VGTAGPSGPSGLPGERGAA--GIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA 687 Query: 769 GDLG 772 G G Sbjct: 688 GATG 691 Score = 413 bits (1061), Expect = e-115 Identities = 262/584 (44%), Positives = 300/584 (51%), Gaps = 62/584 (10%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----------GEAGERGPGGIPGYKG 292 E G PG+ G PG G G+ GERG G PG A G AG G G PG+ G Sbjct: 200 EPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPG 259 Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 G +GE G G G G GP G G G+ G GPPG+PG G G KG G PG G Sbjct: 260 APGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAG 319 Query: 353 SPGAPG-------IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG 404 +PG PG +G G G RG G PG G G G G+PG GP+G PG G Sbjct: 320 APGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSG--E 377 Query: 405 EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPI 463 EG GP GE GS GP GP GL+G G +G G G G MG PG G+ G G++GP Sbjct: 378 EGKRGPNGEAGSAGPPGPPGLRG--SPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPN 435 Query: 464 GPPGPQGPAG----QGLPGSKGEVGQMGPTGPRG-------PVGIGVQGPKGEPGSIGLP 512 G G G G +GLPGS G +G G GP G P IG G +GEPG+IG P Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFP 495 Query: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQ---R 565 G G G+ G G KG AGL GARG GP G +G PGP+G +G KG +G G + Sbjct: 496 GPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQ 555 Query: 566 GLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQ 623 GLPGP GP GE G G G+ G +PGP GP+G+RG PG G G G + RGP G Sbjct: 556 GLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPP 615 Query: 624 GPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP---PGPSG 679 GP G G PG+ G G G GP GLPG G G+ G G KGEPG+RG PG G Sbjct: 616 GPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGI--PGGKGEKGEPGLRGEIGNPGRDG 673 Query: 680 PRG----VGTQGPKGDTGQKGLPGPPGPPG----YGSQGIKGE---QGPQGFPGPKGTMG 728 RG VG GP G TG +G G GP G GS G +GE GP GF GP G G Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAG 733 Query: 729 HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 PG KGE G +G G+ G G G G+ G G GP G G Sbjct: 734 Q--PGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG 775 Score = 412 bits (1060), Expect = e-115 Identities = 260/598 (43%), Positives = 294/598 (49%), Gaps = 97/598 (16%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGN--------------------AQKGEAGERG 283 +G+ G PGPPG G G G GP G PG G G RG Sbjct: 41 RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100 Query: 284 PGGIPGYKGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKG 343 P G G G +G +G G+PG G G G GP GP G G G PG PG G +G Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGR---PGERG 157 Query: 344 EPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERG 401 GP G G PG PG+ G +GI+G G +G G PG GV GEPG PG G G G RG Sbjct: 158 VVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARG 217 Query: 402 LPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGE 456 LPGE G PGP G +GS+G GP G GP+G GP G PG G +GE Sbjct: 218 LPGERGRVGAPGPAGARGSDGSVGP-----------VGPAGPIGSAGPPGFPGAPGPKGE 266 Query: 457 QGIQGPIGPPGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQP 515 G G GP GP GP G+ GLPG G VG P P G+ G KG G G+ G P Sbjct: 267 IGAVGNAGPAGPAGPRGEVGLPGLSGPVGP-----PGNPGANGLTGAKGAAGLPGVAGAP 321 Query: 516 GVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKG 575 G+PG G G G AG GARG G+PGP G +G+ G+KG G G GP GP G Sbjct: 322 GLPGPRGIPGPVGAAGATGARGL-----VGEPGPAGSKGESGNKGEPGSAGPQGPPGPSG 376 Query: 576 EPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG-LSIRGPKGVQGPRGPVGAPGL 634 E G GP G G++ GPPGP G RG PG G G G + GP G +G GP G G Sbjct: 377 EEGKRGPNGEAGSA--GPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGP 434 Query: 635 KGD----GYPGVPGPRGLPGPP---------GPMGLRG-------VGDTGAKGEPGVRGP 674 GD G PG+ GPRGLPG P GP+GL G +G GA+GEPG G Sbjct: 435 NGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGF 494 Query: 675 PGPSGPRG-------------VGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGP---- 717 PGP GP G G +G G G G GPPGP G QG KGEQGP Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV--QGGKGEQGPPGPP 552 Query: 718 --QGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 QG PGP G G G PG++G HGE G G G +GE G PG G G GP G G Sbjct: 553 GFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG 610 Score = 410 bits (1053), Expect = e-114 Identities = 261/598 (43%), Positives = 296/598 (49%), Gaps = 88/598 (14%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGY-------------- 290 G G GPPG G PG KGE G GN G A G AG RG G+PG Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPA--GPAGPRGEVGLPGLSGPVGPPGNPGANG 304 Query: 291 ----KGDKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPG 346 KG G G G PG+ G +G PGP G G G +G+ G PG G KG GNKGEPG Sbjct: 305 LTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPG 364 Query: 347 PPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPG----PIGVGEPGQPGPRGPEGVPGERG 401 GP G PG G G++G GE G G PG PG P G PG G G G PG RG Sbjct: 365 SAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRG 424 Query: 402 LPG-EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGS 453 G G GP G+ G G G G +GL G G+IGP G +GP+G+PG IG Sbjct: 425 ASGPAGVRGPNGDAGRPGEPGLMGPRGL--PGSPGNIGPAGKEGPVGLPGIDGRPGPIGP 482 Query: 454 QGEQGIQGPIGPPGPQGPAG----------------QGLPGSKGEVGQMGPTGPRG-PVG 496 G +G G IG PGP+GP G +G PG G G GP GP+G G Sbjct: 483 AGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGG 542 Query: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK---GEAGLPGARGPEGPPGKGQPGPKGDE 553 G QGP G PG GLPG G GE G G++ GE GLPG GP G +G PG G Sbjct: 543 KGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGE--RGPPGESGAA 600 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G G G++G G PGP+G KGEPG++G G G S GP G G+RG GIPG KGE Sbjct: 601 GPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS--GPSGLPGERGAAGIPGGKGE-- 656 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG-------VGDTGAK 666 KG G RG +G PG DG G PG G PGP G G RG G G + Sbjct: 657 ------KGEPGLRGEIGNPG--RDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPR 708 Query: 667 GEPGVRGPPGPSGPRG----VGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQ 718 G PG RG GP+GP G G G G G++G GP G G G G G GP Sbjct: 709 GSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPN 768 Query: 719 GFPGPKGTMGHGLP----GQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G PGP G+ G G P G G G G G G G G PG GK+GL+GP+GD G Sbjct: 769 GPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826 Score = 317 bits (812), Expect = 4e-86 Identities = 214/520 (41%), Positives = 240/520 (46%), Gaps = 118/520 (22%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGE---RGEC 300 +G G PGP G G PG+ G G G G + G GERG GIPG KG+KGE RGE Sbjct: 609 RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPS--GLPGERGAAGIPGGKGEKGEPGLRGEI 666 Query: 301 GKPGIKGDKGSPGPYGPKGP------RGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354 G PG G +G+PG G GP RG G GP G GP+G G +GE GP GP G Sbjct: 667 GNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFA 726 Query: 355 GAPGI-------GQQGIKGERGQEGRPGAPGPIGV-------GEPGQPGPRGPEGVPGER 400 G G G++G KG +G+ G G GP+G G PG G RG G PG Sbjct: 727 GPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMT 786 Query: 401 GLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGI---PGI-- 451 G PG G PGP G G GP GP G +GL +G +GD GPVG G +G PG Sbjct: 787 GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGL--RGPRGDQGPVGRTGEVGAVGPPGFAG 844 Query: 452 --GSQGEQGIQGPIGPPGPQGPAGQ----GLPGSKGE---------------VGQMGPTG 490 G GE G GP G PGPQG G GLPGS+GE +G GP G Sbjct: 845 EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904 Query: 491 PRGPVGI----GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQ 546 RGP G GV G GE G G PG G PG DG G KGE G PG GP G G Sbjct: 905 ARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG--AAGA 962 Query: 547 PGPKGDEGKKGSKGNQGQRGLPGPEGP------------------KGEPGIMGPFGMPGT 588 PGP G G G GN+G+ G GP GP KGEPG GP G+PG Sbjct: 963 PGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGL 1022 Query: 589 S-------IPGPPGPKGDRGGPGI------------------PGFKGEPGL----SIRGP 619 +PG G GD+G PG G G PG IRGP Sbjct: 1023 KGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGP 1082 Query: 620 KGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRG 659 +G QGP GP G PG PGP G+ G G G Sbjct: 1083 QGHQGPAGPPGPPG--------PPGPPGVSGGGYDFGYDG 1114 Score = 314 bits (805), Expect = 3e-85 Identities = 198/466 (42%), Positives = 240/466 (51%), Gaps = 55/466 (11%) Query: 334 GPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGE--PGQPGPR 391 GP G +G +GE GPPGP G + G G G G PG PGP G+G Q + Sbjct: 33 GPAGDRGPRGERGPPGPPG--------RDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGK 84 Query: 392 GPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIK-GEKGDIGPVGPQGPMGIPG 450 G PG GL G P+G G+ G GPQG QG + + GE G GP G +GP G PG Sbjct: 85 GVGLGPGPMGLMG-----PRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPG 139 Query: 451 IGSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEPGSI 509 GE G G G PG +G G QG G G G G G RG G+ G KG+PG+ Sbjct: 140 --KAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL--DGLKGQPGAP 195 Query: 510 GLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDEGKKGSKGNQGQR 565 G+ G+PG PGE+G G+ G GLPG RG G PG +G G G G G G+ G Sbjct: 196 GVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255 Query: 566 GLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGP 625 G PG GPKGE G +G G G P GP+G+ G PG+ G G PG G G+ G Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAG-----PAGPRGEVGLPGLSGPVGPPGNP--GANGLTGA 308 Query: 626 RGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV-------------GDTGAKGEPGVR 672 +G G PG+ G PG+PGPRG+PGP G G G G++G KGEPG Sbjct: 309 KGAAGLPGVAGA--PGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSA 366 Query: 673 GPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMG-HGL 731 GP GP GP G +G +G G+ G GPPGPPG ++G G +G PG G G G Sbjct: 367 GPQGPPGPSG--EEGKRGPNGEAGSAGPPGPPG-----LRGSPGSRGLPGADGRAGVMGP 419 Query: 732 PGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 PG +G G G G GD G GEPG G +GL G G++G +E Sbjct: 420 PGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE 465 Score = 276 bits (707), Expect = 6e-74 Identities = 176/404 (43%), Positives = 204/404 (50%), Gaps = 46/404 (11%) Query: 245 GDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGDKGERGEC 300 G G GP G G PG KGERG KG G G G GP G G G G RG+ Sbjct: 721 GPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780 Query: 301 GKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG-- 358 G PG+ G G+ G GP GP GI G GPPG G +G +G +G+ GP G G GA G Sbjct: 781 GPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPP 840 Query: 359 --IGQQGIKGERGQEGRPGAPGPIGV-GEPG---QPGPRGPEGVPGERGLPGE----GFP 408 G++G GE G G PG PGP G+ G PG PG RG G+PG G GE G Sbjct: 841 GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIA 900 Query: 409 GPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP-- 465 GP G +G G G G+ G GE G G G GP G G G +GE+G G IGP Sbjct: 901 GPPGARGPPGAVGSPGVNGAP--GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG 958 Query: 466 ----PGPQGPAGQ-GLPGSKGEVGQMGPTGPRGPVGI-------GVQGPKGEPGSIGLPG 513 PGP GP G G G++GE G GP GP G VG G++G KGEPG G G Sbjct: 959 AAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRG 1018 Query: 514 QPGVPGEDGA------AGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGL 567 PG+ G +G AG G+ G PG+ GP GP +G GP G GK G G+ G G Sbjct: 1019 LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP--RGPAGPSGPAGKDGRTGHPGTVGP 1076 Query: 568 PGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGE 611 G GP+G GP G PG PGPPGP G GG G+ G+ Sbjct: 1077 AGIRGPQGHQ---GPAGPPGP--PGPPGPPGVSGGGYDFGYDGD 1115 Score = 222 bits (566), Expect = 1e-57 Identities = 141/306 (46%), Positives = 157/306 (51%), Gaps = 29/306 (9%) Query: 244 KGDPGDPGPPGTHGN------PGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGE 296 +G GD GP G G PG GE+GP G G A G G +G G PG G G Sbjct: 819 RGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGS 878 Query: 297 RGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGA 356 RGE G PG+ G G PGP G GP G +G G G PG G G G G PG G PG Sbjct: 879 RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938 Query: 357 PGIGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPGEGFP-GPKGEK 414 GQ G KGERG PG GP+G G PG GP GP G G RG G P GP G Sbjct: 939 D--GQPGHKGERGY---PGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993 Query: 415 GSEGPTGPQGLQGLSIKGEKGDIGP------VGPQGPMGIPGI-GSQGEQGIQGPIGPPG 467 G GP+GPQG++G KGE G+ GP G G G+PGI G G+QG G +GP G Sbjct: 994 GPRGPSGPQGIRG--DKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051 Query: 468 PQGPAGQGLPGSK----GEVGQMGPTGPRGPVGIGVQGPKGEPGSIGLPGQPGVPGEDGA 523 P+GPAG P K G G +GP G RGP G QGP G PG G PG PGV G Sbjct: 1052 PRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQ--GHQGPAGPPGPPGPPGPPGVSGGGYD 1109 Query: 524 AGKKGE 529 G G+ Sbjct: 1110 FGYDGD 1115 Score = 159 bits (403), Expect = 1e-38 Identities = 98/229 (42%), Positives = 110/229 (48%), Gaps = 33/229 (14%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNA-QKGEAGERGPGGIPGYKGDKGERGECG 301 E G G GPPG G PG G G G PG A + G G GP G G G KGERG G Sbjct: 893 EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPG 952 Query: 302 KPGIKGDKGSPGPYGPKGPRGIQ---------------GITGPPGDPGPKGFQGNKGEPG 346 G G G+PGP+GP GP G G GP G GP+G +G+KGEPG Sbjct: 953 NIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012 Query: 347 PPGPYGSPGAPG-IGQQGIKGERGQEGRPGAPGPIG-VGEPGQPGPRGPEGVPGERGLPG 404 GP G PG G G QG+ G G G GAPG +G G G GP GP G G G PG Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPG 1072 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIG 452 G G +G +G +GP GP GP GP GP G+ G G Sbjct: 1073 TVGPAGIRGPQGHQGPAGPP--------------GPPGPPGPPGVSGGG 1107 Score = 31.2 bits (69), Expect = 5.8 Identities = 14/41 (34%), Positives = 19/41 (46%) Query: 244 KGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGP 284 +G G PGPPG G PG+ G G G+ + + P Sbjct: 1086 QGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAP 1126 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 422 bits (1084), Expect = e-117 Identities = 279/659 (42%), Positives = 329/659 (49%), Gaps = 135/659 (20%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 EKGD G PGPPG G G +G GP G PG+ G RG G PG KG KGERG GK Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 303 --------------PGIKGDKGSPGPYGP----KGPRGIQGITGPPGDPGPKGFQGNKGE 344 PG+ G G PGP G KGP G G+ G G PG G G KGE Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471 Query: 345 PGP--------PGPYGSPGAPGI-GQQGIKGERGQ---EGRPGAPGPIGV-GEPGQPGPR 391 PG PGP G PG PG+ G +GI G +G +G PG+PG G+ G PG PG + Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531 Query: 392 GPEGVPGERG----------LPGE----GFPGPKGEKGSEGPTGPQGLQG----LSIKGE 433 G G+ GE+G +PG+ G PG KG G G G +GL G L++ GE Sbjct: 532 GDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGE 591 Query: 434 KGDIGPVG---------PQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVG 484 KGD GP G P GP G PG G QGE G+QG G PG GP G+ G +GE+ Sbjct: 592 KGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEA--GPRGELS 649 Query: 485 QM----GPTGPRGPVG-IGVQGPKGEPGSIGLPGQPGVPGED-----------GAAGKKG 528 GP GP GP G G QGP G PGS+G G PG+PG D G G KG Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 529 EAGLPGARGPEGPPGK-GQPGPKGDEGKKGSK--------GNQGQRGLPGPEGPKGEPGI 579 + G PG +G G PGK G+PG G G G+K G G G PG G GE G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 580 MGPFGMPGTSIPGPP------GPKGDRGGPGIPGFKGEPGLSIRGPKGVQ---------- 623 +G G+PG +PG P GP+GD G PG PG +G PG I GP+G Q Sbjct: 770 IGLPGLPG--LPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKG 827 Query: 624 --------GPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPP 675 GP+G G PGL G+PG G G+PG G MG +G G G PG+ GPP Sbjct: 828 QQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMG--PLGQRGYPGNPGILGPP 885 Query: 676 GPSG-------PRGVGTQGPKGDTGQKGLPGPPGPPGY----GSQGIKGEQGPQGFPGPK 724 G G P +G GP G+ G G G PG PG G+ G KGEQG +G PGP Sbjct: 886 GEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP- 944 Query: 725 GTMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQ---------GPKGDLGLT 774 + H + G KGE G +G G G+KG G PG PG +GL+ GP+GDLG T Sbjct: 945 SEISHVI-GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGST 1002 Score = 418 bits (1075), Expect = e-116 Identities = 273/629 (43%), Positives = 319/629 (50%), Gaps = 110/629 (17%) Query: 244 KGDPGDPGPPGTHGNPG--IKGERGPKGNPG----NAQKGEAGERGPGGIPGYKG--DKG 295 +GDPG PGPPG G PG I+G RG +G PG Q+G G+ GP G PG G G Sbjct: 791 RGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSG 850 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPG 355 GE G PGI G +G GP G +G G GI GPPG+ G G G G GPPGP G+PG Sbjct: 851 FPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPG 910 Query: 356 APGI-GQQGIKGERGQEGRPGA---------PGPIGV----------------GEPGQPG 389 PG G GI G +GQ G PGA PGP + G PG+ G Sbjct: 911 TPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKG 970 Query: 390 PRGPEGVPGERGLPG----EGFPGPKGEKGSEGPTGPQGLQGL----------SIKGEKG 435 RG G+PG +GL G G PGP+G+ GS G G GL+G+ KG++G Sbjct: 971 NRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRG 1030 Query: 436 DIGPVGPQGPMGIPGI-GSQGEQGIQGPIGP--PGPQGPAGQ-GLPGSKGEVGQMGPTGP 491 +G G G G+PGI G QG++G G PGP GP G GLPG G+ G+MG GP Sbjct: 1031 TLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGP 1090 Query: 492 RGPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG-KGQPGP 549 G +G G +G G PGS GLPG+PG G+ G G KG G PG RGP G PG G PGP Sbjct: 1091 PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP 1150 Query: 550 KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM-GPFGMPGTSIPGPPGPKGDRGGPGIPGF 608 G +G+QG+ G+PGP G KGE G++ P G G PG G KGDRG PG PG Sbjct: 1151 MG------IRGDQGRDGIPGPAGEKGETGLLRAPPGPRGN--PGAQGAKGDRGAPGFPGL 1202 Query: 609 KGEPGL----SIRGPKGVQGPRGPVGAPG--LKGD-GYPGVPGPRGLPGPPGPMGLRGVG 661 G G RGP G++G GP G PG + G G G PG RG PG PGP G G Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262 Query: 662 DTGAKGEPGVRGPPGPSGPRGV-GTQGPKGDTGQKGLPGPPGP---PGY-GSQGIKGEQG 716 G KG+ G G PGP GP G G GP G G G PG PGP PG+ G G+KGE+G Sbjct: 1263 VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322 Query: 717 PQGF---------------------------------PGPKGTMGHGLPGQKGEHGERGD 743 GF PGP GT G PG +GE G G Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE--PGMQGEPGPPGP 1380 Query: 744 VGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G G G+PG GK G GP G+ G Sbjct: 1381 PGNLGPCGPRGKPGKDGKPGTPGPAGEKG 1409 Score = 411 bits (1057), Expect = e-114 Identities = 261/621 (42%), Positives = 309/621 (49%), Gaps = 93/621 (14%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGE-----RGPKGNPG-NAQKGEAGERGPGGIPGYKGD 293 C + G+PG PG PG PG KGE G G PG ++G +GE G G+PG G Sbjct: 722 CPGKMGEPGLPGKPGL---PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778 Query: 294 KGERGECGKPGIKGDKGSPGPYGPKGPRG--IQGITGPPGDPGPKGFQGNKGEPGPPGPY 351 G G G G +GD G PGP G +GP G I+G G G PG G +G +G G GP Sbjct: 779 PGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK 838 Query: 352 GSPGAPGIGQQGIKGERGQEGRPGAPGPIG-------VGEPGQPGPRGPEGVPGERGLPG 404 G PG PG+ + G GE G G PG G +G G PG GP G +GV G G PG Sbjct: 839 GDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPG 898 Query: 405 E-GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-------IGSQGE 456 G PGP G G+ G G G+ G +KG++G G G QG G PG IG +GE Sbjct: 899 AIGPPGPPGNPGTPGQRGSPGIPG--VKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGE 956 Query: 457 QGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG-IGVQGPKGEPGSIGLPGQ 514 G++G G PG +G G G+PG KG G GP GP GP G +G G GEPG G+PG Sbjct: 957 PGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGS 1016 Query: 515 PGVPGEDGAAGKKGEAGLPGARGPEGPPG------------------KGQPGPKGDEGKK 556 G G G+ GK+G G PG G G PG G PGP GD G Sbjct: 1017 MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLP 1076 Query: 557 GSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGD---------------R 600 G G +G+ G PGP G G G G G PG+ +PG PGP GD R Sbjct: 1077 GDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIR 1136 Query: 601 GGPGIPGFKGEPG-LSIRGPKGVQGPRGPVG----------APGLKGD-GYPGVPGPRGL 648 G PG+PGF G PG + IRG +G G GP G PG +G+ G G G RG Sbjct: 1137 GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGA 1196 Query: 649 PGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSG------PRGVGTQGPKGDTGQKGLPGPP 701 PG PG G +G +GD G +G G+ G PGP G P G +GP G G G PGPP Sbjct: 1197 PGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 702 GPPGYGSQGIKGEQGPQGFPGPKGTMGH----------GLPGQKGEHGERGDVGKKGDKG 751 GPPG GIKG++G G PGPKG G G PG G G RGD G +G G Sbjct: 1257 GPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316 Query: 752 EIGEPGSPGKQGLQGPKGDLG 772 GE G+PG G GP G +G Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIG 1337 Score = 397 bits (1021), Expect = e-110 Identities = 272/678 (40%), Positives = 321/678 (47%), Gaps = 152/678 (22%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK------------GEAGERGPGGI 287 C KG+ G PG PGT G PGI G G KG G K G G GP G+ Sbjct: 125 CSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGL 184 Query: 288 PGYKGDKGERGECGKPGIKGDKGSPGPYGP-----------KGPRGIQGITGPPGDP--- 333 PG G G G G PG G G+ GP GP KG RG++G+TGPPG P Sbjct: 185 PGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTV 244 Query: 334 --------------GPKGFQGNKGEPGPPGPYGSP--------GAPGIGQQGIKGERGQE 371 G KG +G GEPGPPGP G P GAP G G++G+ G++ Sbjct: 245 IVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP--GDPGLQGKPGKD 302 Query: 372 GRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPG-------------------EGFPGPK 411 G PG PG GV G G PG G +G+ G++G G EG PGP Sbjct: 303 GVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPP 362 Query: 412 GEKGSEGPTGPQGLQGL------------------SIKGEKGDIGPVGPQGPMGIPGI-G 452 G +G+ GP GP G G+ +KG KG+ G G + MG PG G Sbjct: 363 GPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGTPGSPG 421 Query: 453 SQGEQGIQGPIGPPGPQG--------PAGQGLPGSKGEVGQMGPTGPRGPVGI------G 498 G G+ G GPPGP G P GLPG G G G GP+G G+ Sbjct: 422 CAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPY 481 Query: 499 VQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGS 558 + GP G PG GL G G+PG GAAG KG G PG G G P G PG +GD G KG Sbjct: 482 IPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP--GFPGAQGDPGLKGE 539 Query: 559 KGN----QGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDRGGPGIPGFKGEPG 613 KG +GQ G+PG G +G+PG G G+PGT + G PGPKG+ G G +G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVG-----DTGAKGE 668 G G GP GP G PG G PG+ G +G+PG PGP G G T G Sbjct: 600 --DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGP 657 Query: 669 PGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGP---PGPPGYGSQGIKGEQGPQGFPGPK 724 PG GPPG GP+G G G G G GLPGP PG PG G G G +G QGFPG K Sbjct: 658 PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Query: 725 GTMG-------------HGLPGQKGE--------HGERGDVGKKGDKGEIGE-------- 755 G++G GLPG KGE G G G++G+ GE GE Sbjct: 718 GSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG 777 Query: 756 -PGSPGKQGLQGPKGDLG 772 PG+PG +GL GP+GD G Sbjct: 778 LPGTPGNEGLDGPRGDPG 795 Score = 390 bits (1002), Expect = e-108 Identities = 270/717 (37%), Positives = 323/717 (45%), Gaps = 200/717 (27%) Query: 240 CECEKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE 299 C+ KG+ G+ G PG G+PG KG GP+G P G G +G G+PG G KG RG Sbjct: 41 CDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLP-----GPQGPKGFPGLPGLTGSKGVRGI 95 Query: 300 CGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPG- 358 G PG G G PG G GP G+ G+ PG G +G +G PG PG G PG PG Sbjct: 96 SGLPGFSGSPGLPGTPGNTGPYGLVGV------PGCSGSKGEQGFPGLPGTLGYPGIPGA 149 Query: 359 IGQQGIKG-----------ERGQEGRPGAPGPIGV-GEPGQPGPRGPEGVPGERGLPGEG 406 G +G KG +G G PGAPGP G+ G PG PGP GP G PG G PG Sbjct: 150 AGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAM 209 Query: 407 FP------------GPKGEKGSEGPTGPQGLQGLSI---------------KGEKGDIGP 439 P G KGE+G +G TGP G G I KG+KG +G Sbjct: 210 GPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269 Query: 440 VGPQGPMGIPG------------------------------------------IGSQGEQ 457 GP GP G+PG +G G + Sbjct: 270 PGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIK 329 Query: 458 GIQGPIGPPGPQGP----------AGQGLPGSKGEVGQMGPTGPRGPVGI---------G 498 G +G IGPPG +GP +G PG G G GP GP GP G+ G Sbjct: 330 GQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPG 389 Query: 499 VQGPKGEPGSIGLPGQPGVPGED-----GAAGKKGEAGLPGARGPEGPPGK--GQPGPKG 551 ++G G PG G G+ G PG+D G+ G G GLPG+ GP GPPG + GP G Sbjct: 390 LRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPG 449 Query: 552 DEGKKGSKGNQGQRGLPGPEGPKGEPGIM--------GPFGMPG---------------- 587 D G G G+ G+PG +GPKGEPG++ GP G+PG Sbjct: 450 DHGLPGYLGSP---GIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGA 506 Query: 588 ---TSIPGPPGPKGDRGGPGIPGFKGEPG--------LSIRGPKGVQGPRGPVGAPGLKG 636 PG PG G G PG PG +G+PG L G GV G G G PG KG Sbjct: 507 AGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566 Query: 637 -DGYPGVPGPRGLPGPPGPMGLRG-VGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQ 694 DG PG PG +GLPGP G + L G GD G G+PG G PGP+GP G GP+G+ G Sbjct: 567 LDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGL 626 Query: 695 KGL----------------------------PGPPGPPGY-------GSQGIKGEQGPQG 719 +G PGPPGPPG+ G G G+ G G Sbjct: 627 QGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG 686 Query: 720 FPGPKGTMG------HGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGD 770 PGP G G G PG KG+ G G G G G++GEPG PGK GL G KG+ Sbjct: 687 LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Score = 390 bits (1001), Expect = e-108 Identities = 263/619 (42%), Positives = 309/619 (49%), Gaps = 96/619 (15%) Query: 243 EKGDPGDPGPPGTHGNPGIK--GERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGE- 299 +KG G+PGPPG G PG E+G G+PG +G+ G+ G G PG +G KG RG Sbjct: 263 DKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 300 --CGKPGIKGDKGSPGPYGPKGP---------RGIQGITGPPGDPGPKGFQGNKGEPGPP 348 G+ GIKG KG GP G +GP +G +G GPPG G +G QG G PG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 349 GPYGS--PGAPGI-GQQGIKGERGQEGRP-----GAPGPIG-VGEPGQPGPRGPEGVPGE 399 G GS PG G G G+KG +G+ GRP G PG G G PG PG GP G PG+ Sbjct: 381 GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGD 440 Query: 400 ----RGLPGE-GFPGPKGEKGSEGPTGPQGLQGL------SIKGEKGDIGPVGPQGPMGI 448 +G PG+ G PG G G G GP+G GL I G G G G G GI Sbjct: 441 IVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGI 500 Query: 449 PGIGSQGEQGIQGPIGPPGPQG-PAGQGLPGSKGEVGQMGPTG----PRGPVGI-GVQGP 502 P G QG G++G G PG G P G PG++G+ G G G P G VG+ G G Sbjct: 501 P--GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGL 558 Query: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPG----KGQPGPKGDE----- 553 +G+PG GL G PG PG G G KGE L G +G +GPPG G PGP G Sbjct: 559 RGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY 618 Query: 554 GKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPG 613 G +G G QG +G+PG GP GE G G + T +PGPPGP G G PG G G PG Sbjct: 619 GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSV-STPVPGPPGPPGPPGHPGPQGPPGIPG 677 Query: 614 LSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGV------------- 660 G G G GP G PG+ G G+PG PGP+G G PG G G Sbjct: 678 --SLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKP 735 Query: 661 GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQG 719 G GAKGEP V P GP P G +G G+ G+ GLPG PG PG G++G+ G +G G Sbjct: 736 GLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPG 795 Query: 720 FPGPKGTMG---------------HGLPGQKGEHGERGDVGKKGD-----------KGEI 753 PGP G G GL G KG+ G RG G KGD GE Sbjct: 796 QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855 Query: 754 GEPGSPGKQGLQGPKGDLG 772 G PG PG QG GP G G Sbjct: 856 GSPGIPGHQGEMGPLGQRG 874 Score = 390 bits (1001), Expect = e-108 Identities = 246/531 (46%), Positives = 281/531 (52%), Gaps = 87/531 (16%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK----GEAGERGPGGIPGYKGDKGERG 298 ++G PG PG G G PG KGE+G KGNPG ++ G+ GE G G G G+KG RG Sbjct: 914 QRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973 Query: 299 ECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF---QGNKGEPGP-------- 347 G PG+KG KG PGP GP GPRG G TG PG+PG +G GN G PG Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLG 1033 Query: 348 -PGPYGSPGAPGI-GQQGIKGERG-QEG-RPGAPGPIGVGEPGQPGPRGPEGVPGERGLP 403 PG G PG PGI G QG KGE G EG RPG PGP G+PG PG G +G G+ G P Sbjct: 1034 FPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGP--TGDPGLPGDMGKKGEMGQPGPP 1091 Query: 404 G-------EGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGI----- 451 G EG PG G G G GP G L KG KG +GP G +GP G+PG Sbjct: 1092 GHLGPAGPEGAPGSPGSPGLPGKPGPHG--DLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149 Query: 452 -----GSQGEQGIQGPIG----------PPGPQGPAG----------QGLPGSKGEVGQM 486 G QG GI GP G PPGP+G G G PG G G M Sbjct: 1150 PMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209 Query: 487 GPTGPRGPVGI-GVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKG 545 G GPRGP GI G GP G PG+I +PG+ G G G G PGA GP GPPG Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAI-------IPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262 Query: 546 QPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGI 605 G KGD KGS G+ G +G PG G G PG +G G PG +PGP G G +G PG+ Sbjct: 1263 VIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG--LPGPRGDPGFQGFPGV 1317 Query: 606 PGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGA 665 G KG PG G G GP GP G PG++GD PG LPG PGP G Sbjct: 1318 KGEKGNPG--FLGSIGPPGPIGPKGPPGVRGD--PGTLKIISLPGSPGP--------PGT 1365 Query: 666 KGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPG-YGSQGIKGE 714 GEPG++G PGP GP G +G GP+G G+ G PG PGP G G++G KGE Sbjct: 1366 PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Score = 301 bits (772), Expect = 2e-81 Identities = 186/405 (45%), Positives = 214/405 (52%), Gaps = 30/405 (7%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGK 302 ++G G PG G G PGI G +G KG PG ++ G GP G PG GD G++GE G+ Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ 1087 Query: 303 PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGI-GQ 361 PG G G GP G G G G+ G PG G GF+G KG GPPG G PG PG G Sbjct: 1088 PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGS 1147 Query: 362 QGIKGERGQEGRPGAPGPIG-VGEPG----QPGPR---GPEGVPGERGLPG-EGFPGPKG 412 G G RG +GR G PGP G GE G PGPR G +G G+RG PG G PG KG Sbjct: 1148 PGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKG 1207 Query: 413 EKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQGIQGPIGPPGPQGP 471 G GP GP G++G GP G G + IPG G++G G +G G PGP GP Sbjct: 1208 AMGDAGPRGPTGIEGFP--------GPPGLPGAI-IPGQTGNRGPPGSRGSPGAPGPPGP 1258 Query: 472 AGQGLPGSKGEVGQMGPTGPRGPVG----IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKK 527 G + G KG+ G MG GP+GP G +G G G PG+ GLPG G PG G G K Sbjct: 1259 PGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVK 1318 Query: 528 GEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPG 587 GE G PG G GPP G GPKG G +G G LPG GP G PG G G PG Sbjct: 1319 GEKGNPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376 Query: 588 TSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP 632 PGPPG G G G PG G+PG GP G +G +G G P Sbjct: 1377 P--PGPPGNLGPCGPRGKPGKDGKPGTP--GPAGEKGNKGSKGEP 1417 Score = 214 bits (544), Expect = 5e-55 Identities = 135/304 (44%), Positives = 160/304 (52%), Gaps = 41/304 (13%) Query: 501 GPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKG 560 G KGE G G PG PG PG+ G G +G LPG +GP KG PG G G KG +G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEG---LPGPQGP-----KGFPGLPGLTGSKGVRG 94 Query: 561 NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK 620 G G G G G PG GP+G+ G +PG G KG++G PG+PG G PG+ Sbjct: 95 ISGLPGFSGSPGLPGTPGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIP----- 147 Query: 621 GVQGPRGPVGAPG--------LKGD-GYPGVPGPRGLPGPPGPMGLRGV-GDTGAKGEPG 670 G G +G GAP KGD G PG PGP+GLPGPPG G G G G G PG Sbjct: 148 GAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG 207 Query: 671 VRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGY------------GSQGIKGEQGPQ 718 GP GP G G G KG+ G KGL GPPGPPG +G KG++G Sbjct: 208 AMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 719 GFPGPKGTMGHGLPGQK--GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKE 776 G PGP G G LPG+ E G GD G +G G+ G PG PG +G++G +G GL E Sbjct: 268 GEPGPPGPSG--LPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325 Query: 777 EIIK 780 + IK Sbjct: 326 DGIK 329 Score = 43.1 bits (100), Expect = 0.001 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 7/92 (7%) Query: 730 GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEEIIKLITEICGC- 788 G G+KGE G G G G KG G G PG QG +G G GLT + ++ I+ + G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 789 ------GPKCKETPLELVFVIDSSESVGPENF 814 G P LV V S S G + F Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGF 134 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 420 bits (1079), Expect = e-117 Identities = 276/688 (40%), Positives = 326/688 (47%), Gaps = 167/688 (24%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGN----AQKGEAGERGPGGIPGYKGD---KG 295 +KG G+PG G HG PG G++G +G G+ +KGE GE+G + G G+ KG Sbjct: 305 QKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKG 364 Query: 296 ERGECGKPGIKGDKGSPGPYGPK---GPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 + G G PG KG+KG GP GP G GIQG GPPG G +G +G G PG PGP G Sbjct: 365 DLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG 424 Query: 353 SPGAPGI---------------------GQQGIKGERGQEGRPGAPGPIG----VGEPGQ 387 PG PGI G+KG++G+ G PG PG +G GEPG+ Sbjct: 425 PPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE 484 Query: 388 P------GPRGPEGVPGERGLPGE----------GFPGPKGEKGSEGPTGPQGLQG---- 427 P G RG GV G +G+ GE G PG KG++GS G GP+G G Sbjct: 485 PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544 Query: 428 ---------LSIKGEKGD----IGP---VGPQGPMGIPGIGSQGEQGIQGPIGPPGPQGP 471 IKGEKGD IGP GP+G G PG GE G+ G G PGP+GP Sbjct: 545 PGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 Query: 472 AGQ-GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP------GSIGLPGQPGVPGEDGAA 524 G+ GLPG G G +GP G P G QGP GEP G GLPG PG PG DG Sbjct: 605 KGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVP 664 Query: 525 GKKGEAGLP-------------------------------------GARGPEGPPGK--- 544 G+ G+ GLP G G G PGK Sbjct: 665 GRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDS 724 Query: 545 -------GQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGP 596 G GP G G++G KG++G+RG PG G KG+ G+ G G+PG P GPPG Sbjct: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 Query: 597 KGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAP---------------GLKGDGYPG 641 G G PG G KGE G GP G GP GP G P G+ YPG Sbjct: 785 MGRTGHPGPTGAKGEKGSD--GPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 Query: 642 VPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPP 701 PGP G G PGP VG+ GA G PG+ G PG G R G GP G G G PG P Sbjct: 843 PPGPPGPKGDPGP-----VGEPGAMGLPGLEGFPGVKGDR--GPAGPPGIAGMSGKPGAP 895 Query: 702 GPPGY-GSQGIKGEQGPQGFPGPKGTMGH----------------GLPGQKGEHGERGDV 744 GPPG G G +G G GFPGP+G G G PG +G GERGD Sbjct: 896 GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ 955 Query: 745 GKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G GD+G GE G PG G++G G +G Sbjct: 956 GIPGDRGSQGERGKPGLTGMKGAIGPMG 983 Score = 402 bits (1032), Expect = e-111 Identities = 265/627 (42%), Positives = 317/627 (50%), Gaps = 104/627 (16%) Query: 245 GDPGDPGPPGTHGNPGIKG---------ERGPKGNPGNAQKGEAGERGPGGIPGYKGDKG 295 G PG PGPPG G PGI+G + KGN + G G++G G+PG+ G G Sbjct: 415 GPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVG 474 Query: 296 ERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP---------KGFQGNKGEPG 346 +G+ G+PG KG G G G G QG+ G PGDPGP KG QG+ G G Sbjct: 475 PKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534 Query: 347 PPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEG 406 P GP G G P G+ GI G++G +G G PG I +G PG PGP+G G PG + LPGE Sbjct: 535 PRGPPGDVGLP--GEHGIPGKQGIKGEKGDPGGI-IGPPGLPGPKGEAGPPG-KSLPGE- 589 Query: 407 FPGPKGEKGSEGPTGPQGLQGL-SIKGEKGDIGPVGPQGPMGIPG----IGSQGEQGIQG 461 PG G G+ GP GP+G +GL + G GDIGP G +GIPG G GE GIQG Sbjct: 590 -PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG----IGIPGRTGAQGPAGEPGIQG 644 Query: 462 PIGPPG----PQGPAGQGLPGSKGEVGQMGPTGP------RGPVGI-------------- 497 P G PG P P G+PG G+ G GP G G +G Sbjct: 645 PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVP 704 Query: 498 ------GVQGPKGEP---------GSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPP 542 G +G GEP G IG G PG+PG +G G KGE G PG G +G Sbjct: 705 GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDE 764 Query: 543 G-KGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPG-PKGDR 600 G +G PG G G G G G+ G PGP G KGE G GP G PG PGPPG P +R Sbjct: 765 GLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP--PGPPGIPFNER 822 Query: 601 ----------GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLP 649 GG +P + G PG GPKG GP G GA GL G +G+PGV G RG Sbjct: 823 NGMSSLYKIKGGVNVPSYPGPPGPP--GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPA 880 Query: 650 GPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRG-VGTQGPKGDTGQKGLPGPPGPPGY-- 706 GPPG G+ G GA G PGV G PG GP G +G GP+G +G+ G+ G G PG Sbjct: 881 GPPGIAGMS--GKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938 Query: 707 -----GSQGIKGEQGPQGFPGPKGTMGH----GLPGQKGEHGERGDVGKKGDKGEIGEPG 757 G +G KGE+G QG PG +G+ G GL G KG G G G KG G G G Sbjct: 939 IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 Query: 758 SPGKQGLQGPKGDLGLTKEEIIKLITE 784 PG G+ G D ++ EEI K I + Sbjct: 999 PPGSPGIPGIPAD-AVSFEEIKKYINQ 1024 Score = 375 bits (962), Expect = e-103 Identities = 262/652 (40%), Positives = 307/652 (47%), Gaps = 149/652 (22%) Query: 244 KGDPGDPGPPGTHGNPGIKGERG------PKGNPGNA----------QKGEAGERG-PGG 286 KG+PGDPGPPG G+PG+KG++G P+G PG+ ++G GE+G PGG Sbjct: 506 KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGG 565 Query: 287 I---PGYKGDKGERGECGK-----PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGF 338 I PG G KGE G GK PG+ G+ G+PGP GPKG RG+ G+ G PGD GP+G Sbjct: 566 IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI 625 Query: 339 --------QGNKGEPGPPGPYGSPGAPGI-GQQGIKGERGQEGRPGAPGPIG-------- 381 QG GEPG GP G PG PG G G G G++G+PG PGP G Sbjct: 626 GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLL 685 Query: 382 ------------------------------VGEPGQP---------GPRGPEGVPGERGL 402 GEPG+ GPRGP G+PG G Sbjct: 686 GDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGP 745 Query: 403 PGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPG-IGSQGEQ 457 G G+PG GEKG EG G G I G G GP G G G PG G++GE+ Sbjct: 746 KGSKGERGYPGIPGEKGDEGLQGIPG-----IPGAPGPTGPPGLMGRTGHPGPTGAKGEK 800 Query: 458 GIQGPIGPPGPQGPAG---------QGLPGSKGEVGQMGPTGPRGPVGI-GVQGPKGEPG 507 G GP G PGP GP G L KG V GP GP G G GP GEPG Sbjct: 801 GSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPG 860 Query: 508 SIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGL 567 ++GLPG G PG G +G AG PG G G PG PGP G G+ G +G G G Sbjct: 861 AMGLPGLEGFPG---VKGDRGPAGPPGIAGMSGKPGA--PGPPGVPGEPGERGPVGDIGF 915 Query: 568 PGPEGPKGEPGIMGPFGMPGTS----IPGPPGPKGDRGGPGIPGFKGEPGLSIR-GPKGV 622 PGPEGP G+PGI G G+PG PG GPKG+RG GIPG +G G + G G+ Sbjct: 916 PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGM 975 Query: 623 QGPRGPVGAPGLKGD-GYPGVPGPRGLPGPPGPMG----------------LRGVGDTGA 665 +G GP+G PG KG G PG GP G PG PG LR + A Sbjct: 976 KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 Query: 666 KGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKG 725 ++ P + G GP G G G PG PGP GY +G KGE+G G Sbjct: 1036 VFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGY--RGQKGERGEPGI----- 1088 Query: 726 TMGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGLTKEE 777 GLPG G G +G PGSPG G QGP G G E Sbjct: 1089 ----GLPGSPGLPG----------TSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 Score = 357 bits (915), Expect = 5e-98 Identities = 246/657 (37%), Positives = 305/657 (46%), Gaps = 182/657 (27%) Query: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGPKGFQGNKGEPGPPGPYG 352 +KGE G G PG G KG G G G+ G G PG G +GF+G+KGE G G G Sbjct: 290 NKGEAGLPGAPGSPGQKGHK---GEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG 346 Query: 353 SPGAPGI----GQQGIKGERGQEGRPGAPGPIG-VGEPGQP------GPRGPEGVPGERG 401 G P + G+ G+KG+ G G PG G G G PG P G +GP+G PG+ G Sbjct: 347 EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEG 406 Query: 402 LPG-EGFPGPKGEKGSEGPTGPQGLQGL---------------------SIKGEKGDI-- 437 G G GP G+ G GP GP G+QG+ +KG+KG+ Sbjct: 407 QRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL 466 Query: 438 ----GPVGPQGPMGIPGIG-SQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR 492 G VGP+G G PG ++GE+G +G G G QG G+ PG G G +G G + Sbjct: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE--PGDPGPPGLIGSPGLK 524 Query: 493 GPVG-IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGE-------AGLPGARGPEGPPGK 544 G G G GP+G PG +GLPG+ G+PG+ G G+KG+ GLPG +G GPPGK Sbjct: 525 GQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK 584 Query: 545 ---GQPGPKGDEGKKGSKGNQGQRGLP--------------------GPEGPKGEPGIMG 581 G+PG G+ G G +G +G+RGLP G +GP GEPGI G Sbjct: 585 SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQG 644 Query: 582 PFGMPG-------------------TSIPGPPGP-------------------------- 596 P G+PG +PGPPG Sbjct: 645 PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVP 704 Query: 597 -----KGDRGGPGIPGF------------KGEPGLSIR-GPKGVQGPRGPVGAPGLKGD- 637 KG+ GG G PG +G PG+ R GPKG +G RG G PG KGD Sbjct: 705 GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDE 764 Query: 638 GYPGVPGPRGLPGPPGPMGLRG----VGDTGAKGEPGVRGP---PGPSGPRGV------- 683 G G+PG G PGP GP GL G G TGAKGE G GP PGP GP G+ Sbjct: 765 GLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNG 824 Query: 684 --------------------GTQGPKGDTGQKGLPGPPGPPGY-GSQGIKGEQGPQGFPG 722 G GPKGD G G PG G PG G G+KG++GP G PG Sbjct: 825 MSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPG 884 Query: 723 PKGTMGH-------GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 G G G+PG+ GE G GD+G G +G G+PG GK G+ G +G +G Sbjct: 885 IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941 Score = 296 bits (758), Expect = 7e-80 Identities = 205/521 (39%), Positives = 251/521 (48%), Gaps = 110/521 (21%) Query: 324 QGITGPPGDPGPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGV- 382 +G G PG PG G +G+KGEPG G + GAP G G++G++G G+ G G Sbjct: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLH---GAP-----GFPGQKGEQGFEGSKGETGEK 342 Query: 383 GEPGQPGPRGPEGVPGERGLPGE----GFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIG 438 GE G+ G G+ GE GL G+ G PGPKGEKG GP GP L G +G Sbjct: 343 GEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP--------GSLG 394 Query: 439 PVGPQGPMGIPGI-GSQGEQGIQGPIGPPGPQGPAG-QGLPGSKGEVGQMGPTGPRGPVG 496 GPQGP G G G +G+ G G GPPGP GP G QG+ + G G Sbjct: 395 IQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA 454 Query: 497 IGVQGPKGE------PGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGK-GQPGP 549 G++G KGE PGS+G GQ G PGE G+KG+ G PG G +G G+ G PGP Sbjct: 455 GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP 514 Query: 550 KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFK 609 G G G KG QG G GP GP G+ G+ G G+PG GI G K Sbjct: 515 PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQ--------------GIKGEK 560 Query: 610 GEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEP 669 G+PG I GP G+ GP+G G PG G PG+ G G PGP GP G RG+ P Sbjct: 561 GDPG-GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGL--------P 611 Query: 670 GVRGPPGPSGPRGVG------TQGPKGDTG---QKGLPGPPGPPGY-GSQGIKGEQGPQG 719 GV G PG GP+G+G QGP G+ G +GLPG PG PG G+ G+ G G G Sbjct: 612 GVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG 671 Query: 720 FPGPKGT------MGH-----------------GLPGQKGEHG------------ERGDV 744 PGP G +G GL KGE G +GD+ Sbjct: 672 LPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDI 731 Query: 745 GK------------KGDKGEIGEPGSPGKQGLQGPKGDLGL 773 G KG KGE G PG PG++G +G +G G+ Sbjct: 732 GPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGI 772 Score = 199 bits (507), Expect = 9e-51 Identities = 130/314 (41%), Positives = 164/314 (52%), Gaps = 60/314 (19%) Query: 511 LPGQPGVPGEDGAAGKKGEAGLPGA------RGPEGPPGK-------GQPGPKGDEGKKG 557 LP + + + KGEAGLPGA +G +G PG+ G PG KG++G +G Sbjct: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334 Query: 558 SKGNQGQRGLPGPEGPKGEPGIMGPFGMPGTSIP-GPPGPKGDRGGPGIPGFKGEPGLSI 616 SKG G++G G +G G+ G G+ G P GPPGPKG++G G PG P Sbjct: 335 SKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP---- 390 Query: 617 RGPKGVQGPRGPVGAPGLKG-DGYPGVPGPRGLPGPPGPMGLRGVGDT------------ 663 G G+QGP+GP G G +G G G PG G PGPPGP G++G+ T Sbjct: 391 -GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGN 449 Query: 664 ---------GAKGEPGVRGPPGPSGPRGVG-------TQGPKGDTGQ---------KGLP 698 G KGE G+ G PG GP+G T+G KGD G+ KG P Sbjct: 450 DEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEP 509 Query: 699 GPPGPPG-YGSQGIKGEQGPQGFPGPKGTMGH-GLPGQKGEHGERGDVGKKGDKGE-IGE 755 G PGPPG GS G+KG+QG G GP+G G GLPG+ G G++G G+KGD G IG Sbjct: 510 GDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGP 569 Query: 756 PGSPGKQGLQGPKG 769 PG PG +G GP G Sbjct: 570 PGLPGPKGEAGPPG 583 Score = 172 bits (436), Expect = 2e-42 Identities = 113/284 (39%), Positives = 134/284 (47%), Gaps = 61/284 (21%) Query: 542 PGKGQPGPKGDEGKKGSKGNQGQRGLPGPEGPKGEPGIMGPFGMPGT-SIPGPPGPKGDR 600 P KG+ G G G G KG++G+ G G G G PG G G G+ G G +G++ Sbjct: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 Query: 601 GGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGD----GYPGVPGPRGLPGPPGPMG 656 G P + G GE GL KG GP GP G G KGD G P +PG G+ GP GP G Sbjct: 349 GDPALAGLNGENGL-----KGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 Query: 657 LRGV----GDTGAKGEPGVRGPPGPSGPRGV---------------------GTQGPKGD 691 G G TG G+PG GPPGP G +G+ G +G KG+ Sbjct: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463 Query: 692 TGQKGLPGPPGPPG----------------------YGSQGIKGEQGPQGFPGPKGTMGH 729 TG G PG GP G GSQG+KGE G PGP G +G Sbjct: 464 TGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD---PGPPGLIGS 520 Query: 730 -GLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLG 772 GL GQ+G G G G GD G GE G PGKQG++G KGD G Sbjct: 521 PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 Score = 99.4 bits (246), Expect = 2e-20 Identities = 65/186 (34%), Positives = 80/186 (43%), Gaps = 45/186 (24%) Query: 243 EKGDPGDPGPPGTHGNPGIKGERG------PKGNPGN-AQKGEAGERGPGGIPGYKGDKG 295 ++G PGD G G G PG+ G +G P GN G+ G G G GIPG D Sbjct: 954 DQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAV 1013 Query: 296 ERGECGK--------------------PGIKGDKGSPGPYGPKGPRGIQGITGPPGDPGP 335 E K + + YG GP G G+ GPPGDPGP Sbjct: 1014 SFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGP 1073 Query: 336 KGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRGPEG 395 +G++G KGE G PG G PG+PG+ PG +G PG PG GP+G Sbjct: 1074 QGYRGQKGERGEPG-IGLPGSPGL-----------------PGTSALGLPGSPGAPGPQG 1115 Query: 396 VPGERG 401 PG G Sbjct: 1116 PPGPSG 1121 Score = 33.1 bits (74), Expect = 1.5 Identities = 17/47 (36%), Positives = 26/47 (55%) Query: 727 MGHGLPGQKGEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPKGDLGL 773 M LP ++ + + KG+ G G PGSPG++G +G G+ GL Sbjct: 271 MSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGL 317 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.140 0.428 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 66,138,487 Number of Sequences: 37866 Number of extensions: 5215341 Number of successful extensions: 253335 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 484 Number of HSP's successfully gapped in prelim test: 1299 Number of HSP's that attempted gapping in prelim test: 18213 Number of HSP's gapped (non-prelim): 16350 length of query: 1125 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1012 effective length of database: 13,968,660 effective search space: 14136283920 effective search space used: 14136283920 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.