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Search of human proteins with 14192943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
(1140 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 2602 0.0
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 1494 0.0
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 871 0.0
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 717 0.0
gi|134244285 Notch homolog 3 [Homo sapiens] 282 1e-75
gi|148833508 notch1 preproprotein [Homo sapiens] 281 2e-75
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 281 2e-75
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 276 1e-73
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 276 1e-73
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 275 1e-73
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 275 1e-73
gi|55770876 notch4 preproprotein [Homo sapiens] 274 4e-73
gi|24041035 notch 2 preproprotein [Homo sapiens] 270 8e-72
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 234 5e-61
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 229 9e-60
gi|153946395 tenascin C precursor [Homo sapiens] 220 5e-57
gi|4557679 jagged 1 precursor [Homo sapiens] 218 2e-56
gi|21264602 laminin alpha 5 [Homo sapiens] 208 2e-53
gi|122937283 6720455I24Rik homolog [Homo sapiens] 206 1e-52
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 205 2e-52
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 182 1e-45
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 182 1e-45
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 178 2e-44
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 175 3e-43
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 172 2e-42
gi|143770880 laminin, beta 4 [Homo sapiens] 163 8e-40
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 161 4e-39
gi|110735443 delta-like 1 [Homo sapiens] 150 5e-36
gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens] 145 3e-34
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 145 3e-34
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 2602 bits (6744), Expect = 0.0
Identities = 1140/1140 (100%), Positives = 1140/1140 (100%)
Query: 1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC 60
MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC
Sbjct: 1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC 60
Query: 61 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA 120
TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA
Sbjct: 61 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA 120
Query: 121 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED 180
PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED
Sbjct: 121 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED 180
Query: 181 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC 240
RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC
Sbjct: 181 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC 240
Query: 241 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP
Sbjct: 241 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
Query: 301 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY 360
GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY
Sbjct: 301 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY 360
Query: 361 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD 420
GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD
Sbjct: 361 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD 420
Query: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV
Sbjct: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
Query: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE
Sbjct: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
Query: 541 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC 600
RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC
Sbjct: 541 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC 600
Query: 601 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC 660
ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC
Sbjct: 601 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC 660
Query: 661 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN 720
PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN
Sbjct: 661 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN 720
Query: 721 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF 780
GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF
Sbjct: 721 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF 780
Query: 781 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN 840
MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN
Sbjct: 781 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN 840
Query: 841 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR 900
SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR
Sbjct: 841 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMR 900
Query: 901 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV 960
VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV
Sbjct: 901 VVNADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFV 960
Query: 961 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN 1020
NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN
Sbjct: 961 NLKNVNPGKRGPVGDCTGTLPADWKHGGYLNELGAFGLDRSYMGKSLKDLGKNSEYNSSN 1020
Query: 1021 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT 1080
CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT
Sbjct: 1021 CSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSANRNVYEVEPT 1080
Query: 1081 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE 1140
VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE
Sbjct: 1081 VSVVQGVFSNNGRLSQDPYDLPKNSHIPCHYDLLPVRDSSSSPKQEDSGGSSSNSSSSSE 1140
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 1494 bits (3867), Expect = 0.0
Identities = 598/911 (65%), Positives = 720/911 (79%), Gaps = 8/911 (0%)
Query: 1 MVISLNSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSC 60
MV+SL ++F ++ LN EDPNVCSHWESY+VTVQESY HPFDQIYYT C
Sbjct: 1 MVLSLTGLIAF------SFLQATLALNPEDPNVCSHWESYAVTVQESYAHPFDQIYYTRC 54
Query: 61 TDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIA 120
TDILNWFKCTRHR+SY+TAYR G +TMYRR+SQCCPG+YESG+ C+P C ++CVHGRC++
Sbjct: 55 TDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVS 114
Query: 121 PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCED 180
P+TC CEPGWGG +CSS CD DHWGPHC++RCQC+NGALCNPITGAC CAAGFRGWRCE+
Sbjct: 115 PDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE 174
Query: 181 RCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC 240
C GT+G C CQC++GA+CD GEC C PGYTG +CE+LCPPG HG CE RCPC
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPC 234
Query: 241 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
QNGG CHH+TGEC+CP GW G VC QPCP G FG+NCSQ+C CH+GG CD TGQCHC+
Sbjct: 235 QNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTA 294
Query: 301 GYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLY 360
GY G+RCQ+ECP G++G C++ C C NGG+C +GAC CE G+ G RC+ RLCPEGL+
Sbjct: 295 GYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLH 354
Query: 361 GIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD 420
G C CPC +NT SCHP++G C C+PGWSG +CNE+C G+YG+ CQ C+CQNGAD
Sbjct: 355 GPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGAD 414
Query: 421 CDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGV 480
C S+TG CTCAPGF G C+ C GTYG NCSS C C N CSPVDGSCTCK GW G+
Sbjct: 415 CHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGL 474
Query: 481 DCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
DC++ CPSGTWG CN +C C NG AC+ +DG+C+C PGW G+ CELPC DGT+GLNC+E
Sbjct: 475 DCTLPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSE 534
Query: 541 RCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC 600
CDCSHADGC P TGHC CL GW+G+ CDS C GRWGPNCS+ C C+NG SCSP+DG C
Sbjct: 535 HCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSC 594
Query: 601 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC 660
ECAPGFRG CQRIC PGFYGH C+Q CP CVHSS PCHHI+G+C+CLPGF+GALCN+VC
Sbjct: 595 ECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVC 654
Query: 661 PSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN 720
G FG++CA +C+C NNGTC+PID SCQC+PGWIG DCSQ CPP WGP C H C+CHN
Sbjct: 655 AGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPACFHACSCHN 714
Query: 721 GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGF 780
GA CSA DG C CTPGWTGL+CTQRCP F+GKDC +CQCQNGA CDHISG+CTCRTGF
Sbjct: 715 GASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASCDHISGKCTCRTGF 774
Query: 781 MGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLN 840
G+HCEQ+C GT+GYGC+Q+C+C+NNSTCDH+TGTCYCSPG+KG RCDQA +++ LN
Sbjct: 775 TGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGTCYCSPGFKGIRCDQA-ALMMEELN 833
Query: 841 SLSRTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSM-PAVTYTPAM 899
++ S AL A+ + +GA+ GI++L+ +++ LL LF +R +QK K + P V+YTPAM
Sbjct: 834 PYTKISPALGAERHSVGAVTGIMLLLFLIVVLLGLFAWHRRRQKEKGRDLAPRVSYTPAM 893
Query: 900 RVVNADYTISG 910
R+ + DY++SG
Sbjct: 894 RMTSTDYSLSG 904
Score = 149 bits (375), Expect = 2e-35
Identities = 76/138 (55%), Positives = 94/138 (68%), Gaps = 4/138 (2%)
Query: 994 GAFGLDRSY----MGKSLKDLGKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYV 1049
GA G+DR M K KD K S +SS CSL+SSENPYATIKDPP+L K E YV
Sbjct: 904 GACGMDRRQNTYIMDKGFKDYMKESVCSSSTCSLNSSENPYATIKDPPILTCKLPESSYV 963
Query: 1050 EMKSPARRDSPYAEINNSTSANRNVYEVEPTVSVVQGVFSNNGRLSQDPYDLPKNSHIPC 1109
EMKSP SPY ++ + +++N+N+YEVEPTVSVVQ +N Q+ YDLP+NSHIP
Sbjct: 964 EMKSPVHMGSPYTDVPSLSTSNKNIYEVEPTVSVVQEGCGHNSSYIQNAYDLPRNSHIPG 1023
Query: 1110 HYDLLPVRDSSSSPKQED 1127
HYDLLPVR S ++ +D
Sbjct: 1024 HYDLLPVRQSPANGPSQD 1041
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 871 bits (2250), Expect = 0.0
Identities = 372/732 (50%), Positives = 447/732 (61%), Gaps = 9/732 (1%)
Query: 14 LLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNW---FKCT 70
LLL + A LN DPN CS WES++ T +ES+ PF + C W C
Sbjct: 9 LLLAVGLRLAGTLNPSDPNTCSFWESFTTTTKESHSRPFSLLPSEPCER--PWEGPHTCP 66
Query: 71 RHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGW 130
+ V YRT YR KT +R++ QCC GFYES CVP CA +CVHGRC+APN CQC PGW
Sbjct: 67 QPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGFCVPLCAQECVHGRCVAPNQCQCVPGW 126
Query: 131 GGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGND 190
G +CSS C WGP C C C N + C+P +G C C +G + C C G YG
Sbjct: 127 RGDDCSSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPA 186
Query: 191 CHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVT 250
C RCQC +GA CD TG C CP TG C+ C G G C CQNGGV
Sbjct: 187 CQFRCQC-HGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
Query: 251 GECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDE 310
G CSCP GWMGT+C PCPEG G NCSQEC+CHNGG CD TGQC C+PGYTG+RC++E
Sbjct: 246 GSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREE 305
Query: 311 CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPC 370
CPVG +G CAETC C +C+ +GACLCE GF G+RC RLCP+G YG+ C C C
Sbjct: 306 CPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 371 HLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTC 430
E++ SCHPM+GEC+C PGW+GL+CNE+C +G CQ+ C C +G C + +G C C
Sbjct: 366 DREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQC 425
Query: 431 APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGT 490
APG+ G C++ CP TYG+NCS+RC C+N CSP+DG C CK GW +CS+ CP GT
Sbjct: 426 APGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGT 485
Query: 491 WGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGC 550
WGF CN +CQC + C+ G CTC PGW G C+LPC G +G CA RCDC H+DGC
Sbjct: 486 WGFSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGC 545
Query: 551 HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTT 610
P G C+C GW G C C EG WG NCS C CKNG +C P++G C CAPGFRG +
Sbjct: 546 DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPS 605
Query: 611 CQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCA 670
CQR C PG YG RC C HS CH G C CL G+TG C++ CP G +G+NCA
Sbjct: 606 CQRSCQPGRYGKRC-VPCKCANHSF--CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCA 662
Query: 671 GICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE 730
C C + GTC+P D SC C GW G C + CP +G NC C C G C G
Sbjct: 663 QTCQCHHGGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGA 722
Query: 731 CKCTPGWTGLYC 742
C C PG +G C
Sbjct: 723 CVCPPGHSGAPC 734
Score = 711 bits (1836), Expect = 0.0
Identities = 394/1030 (38%), Positives = 491/1030 (47%), Gaps = 92/1030 (8%)
Query: 136 SSACDGDHWGPHCTSRCQCKNGALCNPITGACH-----CAAGF---RGWRCEDRCEQGTY 187
S C+ GPH + + + H C GF RG+ C C Q
Sbjct: 52 SEPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFYESRGF-CVPLCAQ--- 107
Query: 188 GNDC-HQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVC 246
+C H RC N +C+C PG+ G C C PG GPQC++ C C N C
Sbjct: 108 --ECVHGRCVAPN---------QCQCVPGWRGDDCSSECAPGMWGPQCDKPCSCGNNSSC 156
Query: 247 HHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGER 306
+G CSCPSG C QPC G +G C CQCH G CD TG C C TG
Sbjct: 157 DPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCH-GAPCDPQTGACFCPAERTGPS 215
Query: 307 CQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDK 366
C C GT G C T C NGG G+C C G+ G C CPEG +G C +
Sbjct: 216 CDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLP-CPEGFHGPNCSQ 274
Query: 367 RCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG 426
C CH N C +G+C C PG++G C E C G +G+ C + C C A C G
Sbjct: 275 ECRCH--NGGLCDRFTGQCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANG 332
Query: 427 KCTCAPGFKGIDCSTP-CPLGTYGINCSSRCGC--KNDAVCSPVDGSCTCKAGWHGVDCS 483
C C GF G C+ CP G YG++C + C C ++ C P++G C+C GW G+ C+
Sbjct: 333 ACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCN 392
Query: 484 IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCD 543
CP T G GC C CL+GG C G C CAPG+ G C C TYG+NC+ RC
Sbjct: 393 ESCPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCS 452
Query: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
C +A C P G C C GW +C C G WG +C+ C C + A CSP G C C
Sbjct: 453 CENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGACTCT 512
Query: 604 PGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSG 663
PG+ G CQ C G +G C+ C C HS G C + G C C G+ GA C+ CP G
Sbjct: 513 PGWHGAHCQLPCPKGQFGEGCASRC-DCDHSDG-CDPVHGRCQCQAGWMGARCHLSCPEG 570
Query: 664 RFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAF 723
+G NC+ CTC N GTC P + +C C PG+ G C + C P +G C+ C C N +F
Sbjct: 571 LWGVNCSNTCTCKNGGTCLPENGNCVCAPGFRGPSCQRSCQPGRYGKRCV-PCKCANHSF 629
Query: 724 CSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGR 783
C +G C C GWTG C+Q CP G +G++CA CQC +G C G C C G+ G
Sbjct: 630 CHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGSCICPLGWTGH 689
Query: 784 HCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLS 843
HC + CP GT+G C Q C C C TG C C PG GA C +G +
Sbjct: 690 HCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCR------IGIQEPFT 743
Query: 844 RTSTALPADSYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPAMRVVN 903
T P +GA+ GI +L +V+ L+ALFI YRH QKGKE AV Y+ R+
Sbjct: 744 VMPTT-PVAYNSLGAVIGIAVLGSLVVALVALFIGYRHWQKGKEHHHLAVAYSSG-RLDG 801
Query: 904 ADYTISGTLPHSNGGNANSHYFTNPSYHTLTQCATSPHVNNRDRMTVTKSKNNQLFVNLK 963
++Y + P + SHY++NPSYHTL+QC+ +P N+ LF +L+
Sbjct: 802 SEYVMPDVPP------SYSHYYSNPSYHTLSQCSPNPPPPNK--------VPGPLFASLQ 847
Query: 964 NVNPGKRGPVGDCTGTLPADWKH-----GGYLNELGAFGLDRSYMGKSL--------KDL 1010
N D TLPADWKH G L+ G+ LDRSY K L
Sbjct: 848 NPERPGGAQGHDNHTTLPADWKHRREPPPGPLDR-GSSRLDRSYSYSYSNGPGPFYNKGL 906
Query: 1011 GKNSEYNSSNCSLSSSENPYATIKDPPVLIPKSSECGYVEMKSPARRDSPYAEINNSTSA 1070
E +S SL SSENPYATI+D P L E Y+EMK P P S
Sbjct: 907 ISEEELGASVASL-SSENPYATIRDLPSLPGGPRESSYMEMKGPPSGSPPRQPPQFWDSQ 965
Query: 1071 NRNVYEVEPTVSVVQGVFSNNGRL--------SQDP---------YDLPKNSHIPCHYDL 1113
R +P G + L SQ P YD PKNSHIP HYDL
Sbjct: 966 RRR----QPQPQRDSGTYEQPSPLIHDRDSVGSQPPLPPGLPPGHYDSPKNSHIPGHYDL 1021
Query: 1114 LPVRDSSSSP 1123
PVR S P
Sbjct: 1022 PPVRHPPSPP 1031
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 717 bits (1851), Expect = 0.0
Identities = 316/758 (41%), Positives = 405/758 (53%), Gaps = 32/758 (4%)
Query: 94 CCPGFYESGEMCV---------PHCADKCVHGRCIAPNT---------CQCEPGWGGTNC 135
C PG Y G C P C+++C +C+ P+T C C+ G+ G C
Sbjct: 628 CDPGLY--GRFCHLTCPPWAFGPGCSEEC---QCVQPHTQSCDKRDGSCSCKAGFRGERC 682
Query: 136 SSACDGDHWGPHCTSRCQCKNGALCNPITGAC--HCAAGFRGWRCEDRCEQGTYGNDCHQ 193
+ C+ ++GP C C C G C+ ++G C C AGF+G C C GT+G +C
Sbjct: 683 QAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSS 742
Query: 194 RCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTGE 252
C C GA C VTG+CRCPPG TG CE CP G+ G C++ CP CQ+ C TG
Sbjct: 743 SCSC-GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGA 801
Query: 253 CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECP 312
C C G++G+ C CP G +G +C C C N G C ATG C C+PG+TG CQ C
Sbjct: 802 CLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACD 861
Query: 313 VGTYGVLCAETCQCVNG-GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCH 371
G +G C+ C C G G C +SG CLCEAG+ G RCE + CP+G +G C++RC C
Sbjct: 862 TGHWGPDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQ-CPQGHFGPGCEQRCQC- 919
Query: 372 LENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCA 431
++ +C +SG C C GW G +C C GF+G C+ C+C GA CD+V G C C
Sbjct: 920 -QHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCP 978
Query: 432 PGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
G +G C+ CP TYG NCS C C N A C PV G C C GW G C CP+G +
Sbjct: 979 AGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLY 1038
Query: 492 GFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
G C +C C NGG C+ + G C C GW G CE C C C + C
Sbjct: 1039 GDNCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCD 1098
Query: 552 PTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC 611
P TG C C GW+G C S C G +G C+ C C GA+C G C C PGF G+ C
Sbjct: 1099 PHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGC 1158
Query: 612 QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAG 671
++ C PG +G C+Q C QC + CH TG C C G+ G C + CP GR+G C
Sbjct: 1159 EQACPPGSFGEDCAQMC-QCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQ 1217
Query: 672 ICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGEC 731
+C C N G+C+ +C+C G++G+DC+ CP +GPNC H C C GA C G C
Sbjct: 1218 LCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTC 1277
Query: 732 KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPS 791
C PG G+ C + CP +G C C C+NG C +G C+C G+ GRHCE CP
Sbjct: 1278 LCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPP 1337
Query: 792 GTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
G YG C C C NNSTC+ TGTC C PG+ G C+
Sbjct: 1338 GRYGAACHLECSCHNNSTCEPATGTCRCGPGFYGQACE 1375
Score = 693 bits (1788), Expect = 0.0
Identities = 313/824 (37%), Positives = 392/824 (47%), Gaps = 100/824 (12%)
Query: 102 GEMCVPHCADKCVHGRCIAP-NTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC 160
G C C D G C+ + C C GW G C+ C D +G +C+ C C+NG C
Sbjct: 517 GHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTC 576
Query: 161 NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAF 220
+ +TGAC C G G CED C +G YG C ++C C N C + G C C PG G F
Sbjct: 577 DSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRF 636
Query: 221 CEDLCPP---------------------------------------------GKHGPQCE 235
C CPP G GP C
Sbjct: 637 CHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCW 696
Query: 236 QRCPCQNGGVCHHVTGECS--CPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAAT 293
Q C C G C V+GEC CP+G+ G CGQ CP G FG NCS C C G C T
Sbjct: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC-GGAPCHGVT 755
Query: 294 GQCHCSPGYTGERCQDECPVGTYGVLCAETC-QCVNGGKCYHVSGACLCEAGFAGERCEA 352
GQC C PG TGE C+ +CP G +G+ C E C C + +C +GACLC GF G RC+
Sbjct: 756 GQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQ- 814
Query: 353 RLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQI 412
+CP G YG C RC C N CHP +G C+C PGW+G C C G +G C
Sbjct: 815 DVCPAGWYGPSCQTRCSC--ANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHP 872
Query: 413 CSCQNG-ADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471
C+C G CD+++G C C G+ G C CP G +G C RC C++ A C V G+C
Sbjct: 873 CNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGAC 932
Query: 472 TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQD 531
TC AGW G C CP+G +G C C C G AC+ ++G+C C G RG +C C
Sbjct: 933 TCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPA 992
Query: 532 GTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGA 591
TYG NC++ C C + C P G C C PGW G C C G +G NC C C+NG
Sbjct: 993 HTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGG 1052
Query: 592 SCSPDDGICECAPGFRGTTCQRICSP---------------------------------- 617
+C P G C C G+ G C++ C P
Sbjct: 1053 TCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTG 1112
Query: 618 ---------GFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKN 668
G++G C+Q C C + CHH+TG C C PGFTG+ C + CP G FG++
Sbjct: 1113 DKCQSPCLRGWFGEACAQRC-SCPPGAA-CHHVTGACRCPPGFTGSGCEQACPPGSFGED 1170
Query: 669 CAGICTCT-NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAY 727
CA +C C N C+P +C C G+ G C Q CPP +GP C C C NG C A
Sbjct: 1171 CAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAA 1230
Query: 728 DGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQ 787
G C+C G+ G C CP G +G +C +C C GA CD ++G C C G G CE+
Sbjct: 1231 TGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCER 1290
Query: 788 KCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
CP +G GC C C N C G+C C GW G C+ A
Sbjct: 1291 GCPQNRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELA 1334
Score = 691 bits (1784), Expect = 0.0
Identities = 314/778 (40%), Positives = 395/778 (50%), Gaps = 24/778 (3%)
Query: 93 QCCPGFYESGEMCVPHCAD------------KCVHGRCIAPNT--CQCEPGWGGTNCSSA 138
+C PG +GE C C + C H P T C C PG+ G+ C
Sbjct: 759 RCPPG--RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDV 816
Query: 139 CDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ 198
C +GP C +RC C N C+P TG C CA G+ G+ C+ C+ G +G DC C C
Sbjct: 817 CPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCS 876
Query: 199 NG-ATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPS 257
G +CD ++G C C GY G CE CP G GP CEQRC CQ+G C HV+G C+CP+
Sbjct: 877 AGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPA 936
Query: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYG 317
GW GT C CP G FG +C C C G CDA G C C G G RC + CP TYG
Sbjct: 937 GWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYG 996
Query: 318 VLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
C++ C C NG C V G C C G+ G C + CP GLYG C C C +N +
Sbjct: 997 HNCSQACACFNGASCDPVHGQCHCAPGWMGPSC-LQACPAGLYGDNCRHSCLC--QNGGT 1053
Query: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGI 437
C P+SG CAC GW+GL C + C P C+ C NG CD TG+C C G+ G
Sbjct: 1054 CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCLCPAGWTGD 1113
Query: 438 DCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL 497
C +PC G +G C+ RC C A C V G+C C G+ G C CP G++G C
Sbjct: 1114 KCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQ 1173
Query: 498 TCQCLNGG-ACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH 556
CQC AC+ GTC+CA G+ G C+ C G YG C + C C + C TG
Sbjct: 1174 MCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGA 1233
Query: 557 CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICS 616
CRC G+ G C+ C +GR+GPNC+ C C GA+C P G C C PG G C+R C
Sbjct: 1234 CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCP 1293
Query: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT 676
+G C TC + G CH G C C G+TG C CP GR+G C C+C
Sbjct: 1294 QNRFGVGCEHTCS--CRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCH 1351
Query: 677 NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPG 736
NN TC P +C+C PG+ G C PCPP G C C C +GA C G C C G
Sbjct: 1352 NNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAG 1411
Query: 737 WTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGY 796
+ G +C + C G +G+ C C C GA CD ++G C C G G C C G +G
Sbjct: 1412 FHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Query: 797 GCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLSRTST-ALPADS 853
C CDC + CD ++G C+C G+ G C + G + + SL++ S LPA S
Sbjct: 1472 SCTLHCDCGGGADCDPVSGQCHCVDGYMGPTCREGGPLRLPENPSLAQGSAGTLPASS 1529
Score = 664 bits (1713), Expect = 0.0
Identities = 294/700 (42%), Positives = 361/700 (51%), Gaps = 14/700 (2%)
Query: 139 CDGDHWGPHCTSRCQ-CKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQC 197
C D +G C+ C C+NG C C C G+ G C + C T+G +C C C
Sbjct: 511 CLDDSFGHDCSLTCDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSC 570
Query: 198 QNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPS 257
QNG TCD VTG CRCPPG +G CED CP G +G C ++C C N G CH + G C C
Sbjct: 571 QNGGTCDSVTGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDP 630
Query: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGT--CDAATGQCHCSPGYTGERCQDECPVGT 315
G G C CP FG CS+ECQC T CD G C C G+ GERCQ EC +G
Sbjct: 631 GLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGY 690
Query: 316 YGVLCAETCQCVNGGKCYHVSGAC--LCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLE 373
+G C + C C G C VSG C C AGF GE C + CP G +G+ C C C
Sbjct: 691 FGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC-GQECPVGTFGVNCSSSCSC--- 746
Query: 374 NTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQIC-SCQNGADCDSVTGKCTCAP 432
CH ++G+C C PG +G C C G +G CQ+IC +CQ+ A CD TG C C P
Sbjct: 747 GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLP 806
Query: 433 GFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG 492
GF G C CP G YG +C +RC C ND C P G C+C GW G C C +G WG
Sbjct: 807 GFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWG 866
Query: 493 FGCNLTCQCLNG-GACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
C+ C C G G+C+ + G C C G+ G +CE C G +G C +RC C H C
Sbjct: 867 PDCSHPCNCSAGHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACD 926
Query: 552 PTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTC 611
+G C C GW G C+ C G +G +C C C GA+C +G C C G RG C
Sbjct: 927 HVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAACDAVNGSCLCPAGRRGPRC 986
Query: 612 QRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAG 671
C YGH CSQ C + C + G C C PG+ G C + CP+G +G NC
Sbjct: 987 AETCPAHTYGHNCSQAC--ACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
Query: 672 ICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGEC 731
C C N GTC+P+ C C GW G C + C P C H+ C NG C + G C
Sbjct: 1045 SCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRC 1104
Query: 732 KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPS 791
C GWTG C C G++G+ CA C C GA C H++G C C GF G CEQ CP
Sbjct: 1105 LCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPP 1164
Query: 792 GTYGYGCRQICDCL-NNSTCDHITGTCYCSPGWKGARCDQ 830
G++G C Q+C C N C TGTC C+ G+ G C Q
Sbjct: 1165 GSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQ 1204
Score = 416 bits (1069), Expect = e-116
Identities = 276/903 (30%), Positives = 354/903 (39%), Gaps = 179/903 (19%)
Query: 69 CTRH--RVSYRTAYRHGEKTMYRRKSQCCPGFY----ESGEMCVPHCADKCVH-GRCI-- 119
C H R Y YR T R +CC G+ E G + A C H GRC+
Sbjct: 83 CVGHERRTVYYMGYRQVYTTEARTVLRCCRGWMQQPDEEGCLSAECSASLCFHGGRCVPG 142
Query: 120 APNTCQCEPGWGGTNCSSACDGDHWGPHC-TSRCQCKNGALCNPITGACHCAAGFRGWRC 178
+ C C PG+ G C D C T C++ + P + C C GFR
Sbjct: 143 SAQPCHCPPGFQGPRCQYDVD------ECRTHNGGCQHRCVNTPGSYLCECKPGFRLHTD 196
Query: 179 EDRCEQGTYGNDCHQRCQCQNGATCDH-------VTGECRCPPGYTGAFCEDLCPPGKHG 231
C C NG C H C+C PG+ L G+H
Sbjct: 197 SRTCL-------AINSCALGNGG-CQHHCVQLTITRHRCQCRPGF------QLQEDGRH- 241
Query: 232 PQCEQRCPCQN-GGVCHH----VTG--ECSCPSGWMGTVCGQPCPE-------------G 271
C +R PC N G C H V G C C G+ G+ C + G
Sbjct: 242 --CVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHG 299
Query: 272 RFGKNCSQECQCHNG------------------GTCDAATGQCH--CSPGYTGERCQDEC 311
S +C CH G +C+A G C CS G C C
Sbjct: 300 CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLC--TC 357
Query: 312 PVG----TYGVLCAETCQCVNGGKCYHV------SGACLCEAGFAGERCEARLCPEGLYG 361
P G T C + C + C V C C AG+ RL +G
Sbjct: 358 PRGYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGY-------RLSADGCGC 410
Query: 362 IKCDKRCPCHLENTHSCHPMSG--ECACKPGWSGLYCNETCSP----------------- 402
D+ H C ++G +C+C+ G+ CSP
Sbjct: 411 EDVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGELPFVRP 470
Query: 403 -----GFYGEACQQICSCQNGADCD--SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 455
E Q GAD + + G+ T F +D S +G +CS
Sbjct: 471 LPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDS-------FGHDCSLT 523
Query: 456 C-GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTC 514
C C+N C C C GW G+ C+ CP T+G C+ +C C NGG C+++ G C
Sbjct: 524 CDDCRNGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGKNCSFSCSCQNGGTCDSVTGAC 583
Query: 515 TCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAE 574
C PG G CE C G YG +C ++C+C++ CH G C C PG G C C
Sbjct: 584 RCPPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPP 643
Query: 575 GRWGPNCSLPCYC--KNGASCSPDDGICECAPGFRGTTCQ-------------------- 612
+GP CS C C + SC DG C C GFRG CQ
Sbjct: 644 WAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPV 703
Query: 613 ------------RICSPGFYGHRCSQTCP----------QCVHSSGPCHHITGLCDCLPG 650
+ C GF G C Q CP C PCH +TG C C PG
Sbjct: 704 GVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPG 763
Query: 651 FTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWG 709
TG C CP GR+G C IC C + C+P +C C PG++GS C CP +G
Sbjct: 764 RTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYG 823
Query: 710 PNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNG-ADCD 768
P+C C+C N C G C C PGWTG C + C G +G DC+ C C G CD
Sbjct: 824 PSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCD 883
Query: 769 HISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARC 828
ISG C C G++G CEQ+CP G +G GC Q C C + + CDH++G C C GW+G C
Sbjct: 884 AISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFC 943
Query: 829 DQA 831
+ A
Sbjct: 944 EHA 946
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 282 bits (721), Expect = 1e-75
Identities = 261/954 (27%), Positives = 346/954 (36%), Gaps = 301/954 (31%)
Query: 107 PHCAD--KCVHG-RCIA----PNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGAL 159
P C D C +G RC C C PGW G C D H GP C R C++ +
Sbjct: 41 PPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLE-DPCHSGP-CAGRGVCQSSVV 98
Query: 160 CNPITGACHCAAGFRGWRCE--DRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYT 217
+C C GFRG C D C + C +C G + C CPPGY
Sbjct: 99 AGTARFSCRCPRGFRGPDCSLPDPC----LSSPCAHGARCSVGPDGRFL---CSCPPGYQ 151
Query: 218 GAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGK 275
G C +C PC++GG C + G C CP+G+ G +C P
Sbjct: 152 GRSCR------SDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVP----- 200
Query: 276 NCSQECQCHNGGTCDAA---TGQCHCSPGYTGERCQ---DECP-------------VGTY 316
C+ C NGGTC + T C C PG+ G+ C+ D+CP V TY
Sbjct: 201 -CAPS-PCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVNTY 258
Query: 317 GVLC------------AETCQ-----CVNGGKCYHVSG--ACLCEAGFAGERCEARL--- 354
C + CQ C NGG C++ G +C+C G+ GE C +
Sbjct: 259 NCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDC 318
Query: 355 ---------------------CPEGLYGIKC--DKRC---PCHLENTHSCHPMSGECACK 388
CP G G+ C D C PCH + +P++G C
Sbjct: 319 ATAVCFHGATCHDRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAIC- 377
Query: 389 PGWSGLYCNETCSPGFYGEAC-QQICSCQNGAD-------CDSVTGK--CTCAPGFKGID 438
TC PGF G AC Q + C GA+ C + G C C G+ G
Sbjct: 378 ----------TCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPR 427
Query: 439 CSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSI---RCPSGTWGF 493
C T +N C+N A C G +C C AG+ G C + C S
Sbjct: 428 CET-------DVNECLSGPCRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSS---- 476
Query: 494 GCNLTCQCLNGGAC-NTLDG-TCTCAPGWRGEKCEL--------PCQDGT--------YG 535
C+NGG C + ++G +CTC G+ G C+L PC++G Y
Sbjct: 477 ------PCVNGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYE 530
Query: 536 LNCAE-----RCDCSHADGCHPTTGH------------CRCLPGWSGVHCDSVCAEGRWG 578
CAE CD + D C P H C C PG++G C+S E R
Sbjct: 531 CRCAEGFEGTLCD-RNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVDECRSQ 589
Query: 579 PNCSLPCYCKNGASCSP--DDGICECAPGFRGTTCQ------------------------ 612
P C++G C D +C C G G C+
Sbjct: 590 P-------CRHGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYD 642
Query: 613 RICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC--- 669
+C PGF G C+ +C +S PC C+ G G C +CP G C
Sbjct: 643 CVCQPGFTGPLCNVEINEC--ASSPCGEGG---SCVDGENGFRC--LCPPGSLPPLCLPP 695
Query: 670 AGICT--CTNNGTC--NPIDRSCQCYPGWIGSDCSQ------------------------ 701
+ C ++G C P C C PGW G CSQ
Sbjct: 696 SHPCAHEPCSHGICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG 755
Query: 702 ---PCPPAHWGPNC--IHTCN---CHNGAFCSAYDGE---CKCTPGWTGLYCTQRCPLGF 750
CPP G C + C C +G C + G+ C C GW G C Q
Sbjct: 756 FHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDV---- 811
Query: 751 YGKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCEQ--------------KCPSGTY 794
+CA C C +++G CTC G+ G C+Q C G
Sbjct: 812 --DECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVG 869
Query: 795 GYGC------------RQICDCLNN----STC-DHITG-TCYCSPGWKGARCDQ 830
+ C R + +CL+N TC DH+ TC C PG+ G C+Q
Sbjct: 870 SFSCSCLPGFAGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQ 923
Score = 269 bits (688), Expect = 1e-71
Identities = 271/987 (27%), Positives = 347/987 (35%), Gaps = 312/987 (31%)
Query: 95 CPGFYESGEMCVPH--CADKCVHG-RC-IAPN---TCQCEPGWGGTNCSSACDGDHWGPH 147
CP + + +P + C HG RC + P+ C C PG+ G +C S D G
Sbjct: 108 CPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEP 167
Query: 148 C-----------TSRCQC---------------------KNGALCNP---ITGACHCAAG 172
C + RCQC +NG C +T C C G
Sbjct: 168 CRHGGTCLNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPG 227
Query: 173 FRGWRCEDRCEQGTYGNDCHQRCQCQNGATC-DHV-TGECRCPPGYTGAFC-EDLCPPGK 229
F G CE + DC +C NG TC D V T C+CPP +TG FC ED+
Sbjct: 228 FEGQNCEVNVD------DCPGH-RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDV----- 275
Query: 230 HGPQCE-QRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQ-------------------- 266
+C+ Q C NGG C + G C C +GW G C Q
Sbjct: 276 --DECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAVCFHGATCHDRV 333
Query: 267 -----PCPEGRFGKNCSQE--C---QCHNGGTCDA----ATGQCHCSPGYTGERCQ---D 309
CP G+ G C + C CH CD C C PG+TG C D
Sbjct: 334 ASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVNGRAICTCPPGFTGGACDQDVD 393
Query: 310 ECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG--FAGERCEARLCPEGLYGIKCDKR 367
EC +G C + G+C + G+ LC+ G + G RCE + E L G
Sbjct: 394 ECSIGAN--------PCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV-NECLSG------ 438
Query: 368 CPCHLENTHSCHPMSGE--CACKPGWSGLYCNE-------------------------TC 400
PC N +C G+ C C G++G YC TC
Sbjct: 439 -PCR--NQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVNGFSCTC 495
Query: 401 SPGFYGEACQ---QICS---CQNGADC-DSVTG-KCTCAPGFKGI-------DCSTP--- 442
GF G CQ C+ C+NGA C D G +C CA GF+G DCS
Sbjct: 496 PSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCH 555
Query: 443 ---CPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCS-------IRCPSGTWG 492
C G +C+ G S VD C + HG C RCPSGT G
Sbjct: 556 HGRCVDGIASFSCACAPGYTGTRCESQVD-ECRSQPCRHGGKCLDLVDKYLCRCPSGTTG 614
Query: 493 FGCNLTCQCLNGGACN---TLDGT----CTCAPGWRGEKCELP--------------CQD 531
C + C DG C C PG+ G C + C D
Sbjct: 615 VNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLCNVEINECASSPCGEGGSCVD 674
Query: 532 GTYGLNC--------------AERC---DCSHADGCHPTTG--HCRCLPGWSGVHCDSVC 572
G G C + C CSH C+ G C C PGWSG C
Sbjct: 675 GENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI-CYDAPGGFRCVCEPGWSGPRCSQSL 733
Query: 573 AEGRWGPNCSLPCYCKNGASCSPDDGI---CECAPGFRGTTCQRI--------------- 614
A S PC + G +CS DG+ C C PG +G C+ +
Sbjct: 734 ARDACE---SQPC--RAGGTCS-SDGMGFHCTCPPGVQGRQCELLSPCTPNPCEHGGRCE 787
Query: 615 ----------CSPGFYGHRCSQTCPQCVHSS-----GPCHHITGL--CDCLPGFTGALCN 657
C G+ G RC Q +C + G C ++ G C C G+TG C+
Sbjct: 788 SAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHGGYTGPSCD 847
Query: 658 EVCPSGRFGKNCAGICTCTNNGTCNPI--DRSCQCYPGWIGSDCSQPCPPAHWGPNCIHT 715
+ N C N G+C SC C PG+ G C++ P T
Sbjct: 848 QDI-------NDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPGT 900
Query: 716 CNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISG-Q 773
C H +F C C PG+ G +C Q P DC+ C NG C D ++
Sbjct: 901 CTDHVASFT------CTCPPGYGGFHCEQDLP------DCSP-SSCFNGGTCVDGVNSFS 947
Query: 774 CTCRTGFMGRHCEQK-------------------------CPSGTYGYGCRQICD----- 803
C CR G+ G HC+ + C G C+ + D
Sbjct: 948 CLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQ 1007
Query: 804 -CLNNSTCDHITGTCYCSPGWKGARCD 829
C N C C C PGW G CD
Sbjct: 1008 PCQNGGRCVQTGAYCLCPPGWSGRLCD 1034
Score = 267 bits (683), Expect = 4e-71
Identities = 259/887 (29%), Positives = 336/887 (37%), Gaps = 198/887 (22%)
Query: 60 CTDILNWFKCTRHR------------VSYRTAYRHGEKTMYRR---KSQCCPGFYESGEM 104
C D +N F CT T R+G K + + + +C GF G +
Sbjct: 484 CKDRVNGFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEGF--EGTL 541
Query: 105 C---VPHCA-DKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNG 157
C V C+ D C HGRC IA +C C PG+ GT C S D C S+ C++G
Sbjct: 542 CDRNVDDCSPDPCHHGRCVDGIASFSCACAPGYTGTRCESQVD------ECRSQ-PCRHG 594
Query: 158 ALCNPITGA--CHCAAGFRGWRCE---DRCEQG--TYG--NDCHQR--CQCQNGAT---C 203
C + C C +G G CE D C T+G D R C CQ G T C
Sbjct: 595 GKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPGFTGPLC 654
Query: 204 DHVTGECRCPPGYTGAFCED-------LCPPGKHGPQC---EQRC---PCQNGGVCHHVT 250
+ EC P G C D LCPPG P C C PC +G +C+
Sbjct: 655 NVEINECASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHG-ICYDAP 713
Query: 251 G--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGER 306
G C C GW G C Q ++ + C GGTC D C C PG G +
Sbjct: 714 GGFRCVCEPGWSGPRCSQS-----LARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQ 768
Query: 307 CQDECPVGTYGVLCAETCQCVNGGKCYHVSG---ACLCEAGFAGERCE------ARLCPE 357
C+ P C C +GG+C G C C G+ G RC+ A P
Sbjct: 769 CELLSP-------CTPN-PCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPC 820
Query: 358 GLYGIKCDKR----CPCHLENTH-SCHPMSGECACKPGWSGLYCNE-------TCSPGFY 405
G +GI + C CH T SC +C P +G C + +C PGF
Sbjct: 821 GPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFA 880
Query: 406 GEACQQICS------CQNGADCDSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGC 458
G C + C G D V CTC PG+ G C P +CS C
Sbjct: 881 GPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP------DCSPS-SC 933
Query: 459 KNDAVCSPVDG----SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDG-- 512
N C VDG SC C+ G+ G C C L+ CL+GG C+
Sbjct: 934 FNGGTC--VDGVNSFSCLCRPGYTGAHCQHEADP------C-LSRPCLHGGVCSAAHPGF 984
Query: 513 TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS-- 570
CTC + G +C+ ++ R C + C T +C C PGWSG CD
Sbjct: 985 RCTCLESFTGPQCQTL-------VDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRS 1037
Query: 571 -VCAEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFRGTTCQRICSPGFYGHRCSQT 627
C E L C+ G C +D C C G G+ C++ P
Sbjct: 1038 LPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCL-------- 1089
Query: 628 CPQCVHSSGPCHHITG--LCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPID 685
C H G C G +C+CLPG+ G C + CA C + G+C +
Sbjct: 1090 AQPCQHG-GTCRGYMGGYMCECLPGYNGDNCEDDVDE------CASQ-PCQHGGSCIDLV 1141
Query: 686 RS--CQCYPGWIG-------SDCSQPCPPAHWGPNCIHTCNCHN--GAFCSAYDGECKCT 734
C C PG +G DC P PP GP C+H C + G F C C
Sbjct: 1142 ARYLCSCPPGTLGVLCEINEDDCG-PGPPLDSGPRCLHNGTCVDLVGGF------RCTCP 1194
Query: 735 PGWTGLYC---TQRCPLGFYGKDCALICQCQNGADCDHISG---QCTCRTGFMGRHCE-- 786
PG+TGL C C G C + DC G +C C GF G C+
Sbjct: 1195 PGYTGLRCEADINECRSG--------ACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTV 1246
Query: 787 -QKCPSGTYGYG--CRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
C S +G CR + +T TC+C+ + G RC++
Sbjct: 1247 LSPCESQPCQHGGQCRP-----SPGPGGGLTFTCHCAQPFWGPRCER 1288
Score = 262 bits (669), Expect = 2e-69
Identities = 267/931 (28%), Positives = 333/931 (35%), Gaps = 301/931 (32%)
Query: 94 CCPGFYESGEMC---VPHC---ADKCVH-GRCIAPN---TCQCEPGWGGTNCSSACDGDH 143
C PGF +G C V C A+ C H GRC+ CQC G+ G C + +
Sbjct: 379 CPPGF--TGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECL 436
Query: 144 WGPHCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCE---DRCEQGTYGNDCHQRCQCQ 198
GP C+N A C G C C AGF G CE D C Q C
Sbjct: 437 SGP-------CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDEC----------QSSPCV 479
Query: 199 NGATC-DHVTG-ECRCPPGYTGAFCE---DLCPPGKHGPQCEQRCPCQNGGVCHHVTG-- 251
NG C D V G C CP G++G+ C+ D C PC+NG C
Sbjct: 480 NGGVCKDRVNGFSCTCPSGFSGSTCQLDVDECAS----------TPCRNGAKCVDQPDGY 529
Query: 252 ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDA-ATGQCHCSPGYTGERCQ-- 308
EC C G+ GT+C + + CS + CH+G D A+ C C+PGYTG RC+
Sbjct: 530 ECRCAEGFEGTLCDRNVDD------CSPD-PCHHGRCVDGIASFSCACAPGYTGTRCESQ 582
Query: 309 -DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKR 367
DEC + C +GGKC + LC CP G G+ C+
Sbjct: 583 VDEC----------RSQPCRHGGKCLDLVDKYLCR------------CPSGTTGVNCEV- 619
Query: 368 CPCHLENTHSCHPMSGECA---CKPGWSGLYCNETCSPGFYGEACQ---QICS---CQNG 418
N C S C C+ G + C C PGF G C C+ C G
Sbjct: 620 ------NIDDC--ASNPCTFGVCRDGINRYDC--VCQPGFTGPLCNVEINECASSPCGEG 669
Query: 419 ADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCK--NDAVCSPVDGS--CT 472
C D G +C C PG C P S C + + +C G C
Sbjct: 670 GSCVDGENGFRCLCPPGSLPPLCLPP----------SHPCAHEPCSHGICYDAPGGFRCV 719
Query: 473 CKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT---CTCAPGWRGEKCEL-- 527
C+ GW G RC C + C GG C++ DG CTC PG +G +CEL
Sbjct: 720 CEPGWSGP----RCSQSLARDACE-SQPCRAGGTCSS-DGMGFHCTCPPGVQGRQCELLS 773
Query: 528 PCQDGTYGLNCAERCDCSHADGCHPTTGH---CRCLPGWSGVHC----DSVCAEGRWGPN 580
PC C H C G C C GW G C D GP+
Sbjct: 774 PCTPNP----------CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPH 823
Query: 581 --C-----SLPCYCKNG---ASCSPDDGICECAPGFRGTTCQR-------ICSPGFYGHR 623
C S C C G SC D C+ P G +CQ C PGF G R
Sbjct: 824 GICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPR 883
Query: 624 CSQTCPQCVHSSGPC-------HHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCT 676
C++ +C+ S PC H + C C PG+ G C + P +C+ +C
Sbjct: 884 CARDVDECL--SNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLP------DCSP-SSCF 934
Query: 677 NNGTCNPIDR----SCQCYPGWIGSDC--------SQPC------PPAH----------- 707
N GTC +D SC C PG+ G+ C S+PC AH
Sbjct: 935 NGGTC--VDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESF 992
Query: 708 WGPNC---IHTCN---CHNGAFCSAYDGECKCTPGWTGLYCTQR---------------- 745
GP C + C+ C NG C C C PGW+G C R
Sbjct: 993 TGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLE 1052
Query: 746 -------------------CPLGFYGKDC------ALICQCQNGADCDHISG--QCTCRT 778
CP G G C L CQ+G C G C C
Sbjct: 1053 QLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLP 1112
Query: 779 GFMGRHCEQ-------------------------KCPSGTYGYGCRQICD---------- 803
G+ G +CE CP GT G C D
Sbjct: 1113 GYNGDNCEDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDS 1172
Query: 804 ---CLNNSTCDHITG--TCYCSPGWKGARCD 829
CL+N TC + G C C PG+ G RC+
Sbjct: 1173 GPRCLHNGTCVDLVGGFRCTCPPGYTGLRCE 1203
Score = 206 bits (524), Expect = 1e-52
Identities = 188/657 (28%), Positives = 234/657 (35%), Gaps = 160/657 (24%)
Query: 224 LCPPGKHGPQCEQRCPCQNGGVCHHVTGE---CSCPSGWMGTVCG--QPCPEGRFGKNCS 278
L PG P C PC NGG C + C CP GW+G C PC G C+
Sbjct: 33 LAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGP----CA 88
Query: 279 QECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA 338
C + A C C G+ G C P CA +C G +
Sbjct: 89 GRGVCQSSVVAGTARFSCRCPRGFRGPDCS--LPDPCLSSPCAHGARCSVGPDGRFL--- 143
Query: 339 CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE 398
C C G+ G C + + +C PC T P S C C G++G C
Sbjct: 144 CSCPPGYQGRSCRSDVD-------ECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 399 TCSPGFYGEACQQICSCQNGADC---DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 455
P C C+NG C +T C C PGF+G +C +N
Sbjct: 197 PAVP------CAP-SPCRNGGTCRQSGDLTYDCACLPGFEGQNCE---------VNVDDC 240
Query: 456 CG--CKNDAVCSPVDG----SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ-CLNGGAC- 507
G C N C VDG +C C W G C+ C L C NGG C
Sbjct: 241 PGHRCLNGGTC--VDGVNTYNCQCPPEWTGQFCTEDVDE------CQLQPNACHNGGTCF 292
Query: 508 NTLDG-TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWS 564
NTL G +C C GW GE C D CA C H CH +C C G +
Sbjct: 293 NTLGGHSCVCVNGWTGESCSQNIDD------CATAV-CFHGATCHDRVASFYCACPMGKT 345
Query: 565 GV--HCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGH 622
G+ H D C S PC+ +D IC+ P C C PGF G
Sbjct: 346 GLLCHLDDACV--------SNPCH---------EDAICDTNPVNGRAICT--CPPGFTGG 386
Query: 623 RCSQTCPQCVHSSGPCHHI--------TGLCDCLPGFTGALCN---EVCPSGRFGKNCAG 671
C Q +C + PC H+ + LC C G+TG C C SG
Sbjct: 387 ACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDVNECLSG-------- 438
Query: 672 ICTCTNNGTCNPIDR----SCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAY 727
C N TC +DR +C C G+ G+ C P C NG C
Sbjct: 439 --PCRNQATC--LDRIGQFTCICMAGFTGTYCEVDIDECQSSP-------CVNGGVCKDR 487
Query: 728 DGECKCTPGWTGLYCTQRCPLGFYGKDCAL------ICQCQNGADC-DHISG-QCTCRTG 779
CT CP GF G C L C+NGA C D G +C C G
Sbjct: 488 VNGFSCT-----------CPSGFSGSTCQLDVDECASTPCRNGAKCVDQPDGYECRCAEG 536
Query: 780 FMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDH-------ITGTCYCSPGWKGARCD 829
F G C+ R + DC + C H + +C C+PG+ G RC+
Sbjct: 537 FEGTLCD------------RNVDDC-SPDPCHHGRCVDGIASFSCACAPGYTGTRCE 580
Score = 201 bits (512), Expect = 3e-51
Identities = 220/826 (26%), Positives = 263/826 (31%), Gaps = 295/826 (35%)
Query: 94 CCPGFY-ESGEMCVPHCADKCVHG-RC-IAPN---TCQCEPGWGGTNC------------ 135
C PG E+ P + C HG RC AP C C GW G C
Sbjct: 760 CPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAP 819
Query: 136 --------------SSACDGDHWGPHCTSRCQ------CKNGALCNPITGA--CHCAAGF 173
S C G + GP C C NG C G+ C C GF
Sbjct: 820 CGPHGICTNLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGF 879
Query: 174 RGWRCED------------------------RCEQGTYGNDCHQRC------QCQNGATC 203
G RC C G G C Q C NG TC
Sbjct: 880 AGPRCARDVDECLSNPCGPGTCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTC 939
Query: 204 -DHVTG-ECRCPPGYTGAFCED-----LCPPGKHG--------------------PQCE- 235
D V C C PGYTGA C+ L P HG PQC+
Sbjct: 940 VDGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQT 999
Query: 236 -----QRCPCQNGGVCHHVTGECSCPSGWMGTVC-------------------------G 265
R PCQNGG C C CP GW G +C G
Sbjct: 1000 LVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGG 1059
Query: 266 Q----------PCPEGRFGKNCSQECQ------CHNGGTCDAATG--QCHCSPGYTGERC 307
Q CPEGR G +C QE C +GGTC G C C PGY G+ C
Sbjct: 1060 QCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNC 1119
Query: 308 QDE-------------------------CPVGTYGVLC---AETC----------QCVNG 329
+D+ CP GT GVLC + C +C++
Sbjct: 1120 EDDVDECASQPCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHN 1179
Query: 330 GKCYHVSGA--CLCEAGFAGERCEARL--CPEGLYGIKCDKRCPCHLENTHSCHPMSG-- 383
G C + G C C G+ G RCEA + C G CH +T C G
Sbjct: 1180 GTCVDLVGGFRCTCPPGYTGLRCEADINECRSG----------ACHAAHTRDCLQDPGGG 1229
Query: 384 -ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADC-------DSVTGKCTCAPGFK 435
C C G+SG C SP C+ CQ+G C +T C CA F
Sbjct: 1230 FRCLCHAGFSGPRCQTVLSP------CES-QPCQHGGQCRPSPGPGGGLTFTCHCAQPFW 1282
Query: 436 GIDC--------STPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSI--R 485
G C CP+ G+ C +P C C G G C
Sbjct: 1283 GPRCERVARSCRELQCPV---GVPCQQ----------TPRGPRCACPPGLSGPSCRSFPG 1329
Query: 486 CPSGTWGFGCNLTCQCLNGGACNTLD----GTCTCAPGWRGEKCELPCQDGTYGLNCAER 541
P G C CL+GG+C C CA GW G +CE P +E
Sbjct: 1330 SPPGASNASC-AAAPCLHGGSCRPAPLAPFFRCACAQGWTGPRCEAPAA----APEVSEE 1384
Query: 542 CDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICE 601
C A C G R CD C N C D G C
Sbjct: 1385 PRCPRA-ACQAKRGDQR---------CDREC----------------NSPGCGWDGGDCS 1418
Query: 602 CAPGFRGTTCQRI-CSPGFYGHRCSQTC--PQCVHSSGPCHHITGLCDCLPGFTGALCNE 658
+ G C+ + C F RC C P C++ + CH G CN
Sbjct: 1419 LSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCH---------AGGRERTCNP 1469
Query: 659 VCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCP 704
V + K CA +G C+ + +C GW G DC+ P
Sbjct: 1470 V-----YEKYCADHFA---DGRCDQGCNTEEC--GWDGLDCASEVP 1505
Score = 129 bits (325), Expect = 1e-29
Identities = 146/580 (25%), Positives = 190/580 (32%), Gaps = 208/580 (35%)
Query: 94 CCPGFYESGEMCVPHCADKCVHGRCIAPNTCQC-EPGWGGTNCSSACDGDHWGPHCT--- 149
C PG+ +G C H AD C+ C+ C PG+ T C GP C
Sbjct: 950 CRPGY--TGAHC-QHEADPCLSRPCLHGGVCSAAHPGFRCT-----CLESFTGPQCQTLV 1001
Query: 150 ---SRCQCKNGALCNPITGACHCAAGFRGWRCEDR------------------------- 181
SR C+NG C C C G+ G C+ R
Sbjct: 1002 DWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQC 1061
Query: 182 ----------CEQGTYGNDCHQRCQ------CQNGATCDHVTGE--CRCPPGYTGAFCED 223
C +G G+ C Q CQ+G TC G C C PGY G CED
Sbjct: 1062 VDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCED 1121
Query: 224 LCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKNCSQEC 281
+C + PCQ+GG C + CSCP G +G +C + G
Sbjct: 1122 ------DVDECASQ-PCQHGGSCIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGP 1174
Query: 282 QCHNGGTCDAATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVS 336
+C + GTC G +C C PGYTG RC+ +EC G C GG
Sbjct: 1175 RCLHNGTCVDLVGGFRCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGG-----G 1229
Query: 337 GACLCEAGFAGERCEARL-----------------------------CPEGLYGIKCDK- 366
CLC AGF+G RC+ L C + +G +C++
Sbjct: 1230 FRCLCHAGFSGPRCQTVLSPCESQPCQHGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERV 1289
Query: 367 -------RCPCHLENTHSCHPMSGECACKPGWSGLYCNET--CSPGFYGEACQQICSCQN 417
+CP + + P CAC PG SG C PG +C C +
Sbjct: 1290 ARSCRELQCPVGVPCQQT--PRGPRCACPPGLSGPSCRSFPGSPPGASNASCAA-APCLH 1346
Query: 418 GADCDSVT----GKCTCAPGFKGIDCSTP-----------CP------------------ 444
G C +C CA G+ G C P CP
Sbjct: 1347 GGSCRPAPLAPFFRCACAQGWTGPRCEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECN 1406
Query: 445 ---LGTYGINCS---------------------SRC--GCKNDA---------------V 463
G G +CS SRC C + A
Sbjct: 1407 SPGCGWDGGDCSLSVGDPWRQCEALQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERT 1466
Query: 464 CSPV----------DGSC-----TCKAGWHGVDCSIRCPS 488
C+PV DG C T + GW G+DC+ P+
Sbjct: 1467 CNPVYEKYCADHFADGRCDQGCNTEECGWDGLDCASEVPA 1506
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 281 bits (720), Expect = 2e-75
Identities = 269/954 (28%), Positives = 343/954 (35%), Gaps = 279/954 (29%)
Query: 101 SGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTS---RCQ---- 153
+G +C H D C+ C + C P G C+ C + GP C+ C
Sbjct: 366 TGLLC--HLNDACISNPCNEGSNCDTNPVNGKAICT--CPSGYTGPACSQDVDECSLGAN 421
Query: 154 -CKNGALCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE- 209
C++ C G+ C C G+ G RCE N+C CQN ATC GE
Sbjct: 422 PCEHAGKCINTLGSFECQCLQGYTGPRCEIDV------NECVSN-PCQNDATCLDQIGEF 474
Query: 210 -CRCPPGYTGAFCE---DLCP--PGKHGPQC-----EQRCPCQNG---GVCHHVTGECSC 255
C C PGY G CE D C P H +C E +C C G +C + EC+
Sbjct: 475 QCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECAS 534
Query: 256 PSGWMGTVCGQP-------CPEGRFGKNCS---QECQ---CHNGGTCDA-ATGQCHCSPG 301
G C C EG G +C EC CH G D AT C C PG
Sbjct: 535 TPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPG 594
Query: 302 YTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARL-- 354
YTG C+ +EC + C +GG C A C C G G CE L
Sbjct: 595 YTGHHCETNINEC----------SSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDD 644
Query: 355 -----CPEGLYGIKCDK-RCPCHLENTHS-CHPMSGECA---------CKPGWSGLYCNE 398
C G K D C C T S C+ ECA C+ G +G C
Sbjct: 645 CASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCR- 703
Query: 399 TCSPGFYGEACQQICS------CQNGADCDSVTG-KCTCAPGFKGIDCSTPCPLGTYGIN 451
C G++ C + C +GA DS+ G KC C PG+ G +C
Sbjct: 704 -CPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDIN------NNE 756
Query: 452 CSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCSIR--------------CPSGTWGFGC 495
C S C N C + CTC+ G+ G +C C G+ C
Sbjct: 757 CESN-PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKC 815
Query: 496 NL-------TCQ----------CLNGGACNTLDG----TCTCAPGWRGEKCELPCQDGTY 534
N TC+ C NGG C + +C C GW+G+ CE+
Sbjct: 816 NCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVD------ 869
Query: 535 GLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGAS 592
+N C H C T G C C G+SG +C++ + R P C NG S
Sbjct: 870 -INECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNP-------CHNGGS 921
Query: 593 CSPDDGI----CECAPGFRGTTCQR-------------------------ICSPGFYGHR 623
C+ DGI C+C PGFRGT C+ C GF G
Sbjct: 922 CT--DGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIH 979
Query: 624 CSQTCPQCVHSS----GPCHHITGL----CDCLPGFTGALCNE----------------- 658
C P C SS G C + G+ C C PGFTG+ C
Sbjct: 980 CENNTPDCTESSCFNGGTC--VDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQ 1037
Query: 659 --------VCPSGRFGKNCAGI------CTCTNNGTC--NPIDRSCQCYPGWIGSDCSQP 702
CP G G NC + C N G C C+C GW G C P
Sbjct: 1038 DGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVP 1097
Query: 703 ---CPPA------------HWGPNCI-----HTCNC---HNGAFCSAYDGECKCTPGWTG 739
C A G C+ H C C + G++C EC +P G
Sbjct: 1098 SVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNG 1157
Query: 740 LYCTQ-------RCPLGFYGKDCA------LICQCQNGADCDHISG--QCTCRTGFMGRH 784
CT +C G++G +C+ L CQNG C + +C+C G G H
Sbjct: 1158 ATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 785 CEQKCPSGTYGYGCRQICD-------CLNNSTC-DHITG-TCYCSPGWKGARCD 829
CE C D C NN TC D + G +C C PG+ G RC+
Sbjct: 1218 CEINVDD------CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE 1265
Score = 276 bits (707), Expect = 6e-74
Identities = 268/992 (27%), Positives = 354/992 (35%), Gaps = 348/992 (35%)
Query: 117 RCIAPN-TC----QCEPGWGGTNCSSACDGDHWGPHCTS-----RCQCKNGALCNPITG- 165
RC P TC +CE G C C G GP C CKN C+ +
Sbjct: 23 RCSQPGETCLNGGKCEAANGTEAC--VCGGAFVGPRCQDPNPCLSTPCKNAGTCHVVDRR 80
Query: 166 -----ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVT---GECRCPPGYT 217
AC CA GF G C + N C+NG TCD +T +CRCPPG++
Sbjct: 81 GVADYACSCALGFSGPLCLTPLDNACLTN------PCRNGGTCDLLTLTEYKCRCPPGWS 134
Query: 218 GAFCEDL------------------------CPPGKHGPQCEQ---RCP-----CQNGGV 245
G C+ CPP HGP C Q C C++GG
Sbjct: 135 GKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVNECGQKPGLCRHGGT 194
Query: 246 CHHVTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC---DAATGQCHCSP 300
CH+ G C C + G C +P CS C NGGTC T +C C P
Sbjct: 195 CHNEVGSYRCVCRATHTGPNCERPYVP------CSPS-PCQNGGTCRPTGDVTHECACLP 247
Query: 301 GYTGERCQ---DECP-------------VGTYGVLC------------AETCQ-----CV 327
G+TG+ C+ D+CP V TY C + CQ C
Sbjct: 248 GFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQ 307
Query: 328 NGGKCYHVSGA--CLCEAGFAGERCEARL------------------------CPEGLYG 361
NGG C++ G C+C G+ GE C + CP G G
Sbjct: 308 NGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCECPHGRTG 367
Query: 362 IKC--DKRC---PCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQ---IC 413
+ C + C PC+ + +P++G+ C TC G+ G AC Q C
Sbjct: 368 LLCHLNDACISNPCNEGSNCDTNPVNGKAIC-----------TCPSGYTGPACSQDVDEC 416
Query: 414 S-----CQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSP 466
S C++ C + G +C C G+ G C +N C+NDA C
Sbjct: 417 SLGANPCEHAGKCINTLGSFECQCLQGYTGPRCE-------IDVNECVSNPCQNDATCLD 469
Query: 467 VDG--SCTCKAGWHGVDCSI-------------------------RCPSGTWGFGCN--- 496
G C C G+ GV C + CP+G G C
Sbjct: 470 QIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDV 529
Query: 497 ---LTCQCLNGGACNTLDG----TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADG 549
+ C NG C LDG TC C G+ G CE+ + CD D
Sbjct: 530 DECASTPCKNGAKC--LDGPNTYTCVCTEGYTGTHCEVD----------IDECD---PDP 574
Query: 550 CH-------PTTGHCRCLPGWSGVHCDS-------------------------VCAEGRW 577
CH T C C PG++G HC++ C +G
Sbjct: 575 CHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTT 634
Query: 578 GPNCSL------PCYCKNGASCSPDDGI-CECAPGFRGTTCQ--------------RICS 616
GPNC + C +G DG C C PG+ G+ C C
Sbjct: 635 GPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCE 694
Query: 617 PGFYGHRCSQTCPQCVH-----------SSGPCHH------ITGL-CDCLPGFTGALC-- 656
G G C CP+ H +S PC H + G CDC PG++G C
Sbjct: 695 DGINGFTC--RCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDI 752
Query: 657 -NEVCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGSDC--------SQPCPP 705
N C S C N GTC + C C G+ G +C S PC
Sbjct: 753 NNNECESN----------PCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPC-- 800
Query: 706 AHWGPNCI-----HTCNC---HNGAFCSAYDGECKCTPGWTGLYCTQR---------CPL 748
+ G CI + CNC + GA C C +P G C Q CP
Sbjct: 801 LNQG-TCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPT 859
Query: 749 GFYGKDC------ALICQCQNGADCDHISG--QCTCRTGFMGRHCEQKCPSGTYGYGCRQ 800
G+ G+ C ++ C++GA C + G +C C+ G+ GR+CE CR
Sbjct: 860 GWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDD------CRP 913
Query: 801 ICDCLNNSTC-DHI-TGTCYCSPGWKGARCDQ 830
C N +C D I T C C PG++G C++
Sbjct: 914 -NPCHNGGSCTDGINTAFCDCLPGFRGTFCEE 944
Score = 269 bits (688), Expect = 1e-71
Identities = 266/1019 (26%), Positives = 347/1019 (34%), Gaps = 311/1019 (30%)
Query: 86 TMYRRKSQCCPGFYESGEMCV---PHCADKCVHG-RCI---APNTCQCEPGWGGTNCSS- 137
T+ K +C PG+ SG+ C P ++ C +G +C+ A C C P + G C
Sbjct: 121 TLTEYKCRCPPGW--SGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQD 178
Query: 138 --------------------------ACDGDHWGPHCT------SRCQCKNGALCNP--- 162
C H GP+C S C+NG C P
Sbjct: 179 VNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGD 238
Query: 163 ITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE 222
+T C C GF G CE+ + GN+C C +G T CRCPP +TG +C
Sbjct: 239 VTHECACLPGFTGQNCEENIDDCP-GNNCKNGGACVDGVN----TYNCRCPPEWTGQYCT 293
Query: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQ-------------- 266
+ + P CQNGG CH+ G C C +GW G C +
Sbjct: 294 EDVDECQLMPNA-----CQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGA 348
Query: 267 -----------PCPEGRFGKNC--SQEC---QCHNGGTCDA----ATGQCHCSPGYTGER 306
CP GR G C + C C+ G CD C C GYTG
Sbjct: 349 TCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPA 408
Query: 307 CQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYG 361
C DEC +G C + GKC + G+ C C G+ G RCE +
Sbjct: 409 CSQDVDECSLGAN--------PCEHAGKCINTLGSFECQCLQGYTGPRCEIDVN------ 454
Query: 362 IKCDKRCPCHLENTHSCHPMSGE--CACKPGWSGLYC----------------------N 397
+C PC +N +C GE C C PG+ G++C N
Sbjct: 455 -ECVSN-PC--QNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKIN 510
Query: 398 E---TCSPGFYGEACQ---QICS---CQNGADC--DSVTGKCTCAPGFKGIDCST----- 441
E C GF G CQ C+ C+NGA C T C C G+ G C
Sbjct: 511 EFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDEC 570
Query: 442 ---PCPLGTYGINCSS-RCGCKNDAV---CSPVDGSCTCKAGWHGVDCSIR-------CP 487
PC G+ ++ C C+ C C+ + HG C R C
Sbjct: 571 DPDPCHYGSCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCL 630
Query: 488 SGTWGFGCNLTCQ------CLNGGACNTLDG-TCTCAPGWRGEKCEL------------- 527
GT G C + C +G + +DG C C PG+ G C +
Sbjct: 631 KGTTGPNCEINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNG 690
Query: 528 -PCQDGTYGLNC--------------AERCD---CSHADGCHPTTGH-CRCLPGWSGVHC 568
C+DG G C C+ C H G+ C C PGWSG +C
Sbjct: 691 GTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNC 750
Query: 569 DSVCAEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFRGTTCQR------------- 613
D E P C NG +C +C C GF G CQ
Sbjct: 751 DINNNECESNP-------CVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLNQ 803
Query: 614 -ICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNE---------VCPSG 663
C G++C+ P ++ C + C P G C + VCP+G
Sbjct: 804 GTCIDDVAGYKCNCLLP---YTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTG 860
Query: 664 RFGKNC------AGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCP-----PAHWGP 710
G+ C + C + +C C C G+ G +C P H G
Sbjct: 861 WQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGG 920
Query: 711 NC---IHT--CNC---HNGAFCSAYDGECKCTPGWTGLYCTQ-------RCPLGFYGKDC 755
+C I+T C+C G FC EC P G CT CP GF G C
Sbjct: 921 SCTDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHC 980
Query: 756 ------ALICQCQNGADC-DHISG-QCTCRTGFMGRHCEQK------------------- 788
C NG C D I+ C C GF G +C+
Sbjct: 981 ENNTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGC 1040
Query: 789 ------CPSGTYGYGCRQI---CD---CLNNSTC--DHITGTCYCSPGWKGARCDQAGV 833
CP G G C+ + CD C N C H C C GW G CD V
Sbjct: 1041 GSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSV 1099
Score = 259 bits (661), Expect = 1e-68
Identities = 249/890 (27%), Positives = 310/890 (34%), Gaps = 268/890 (30%)
Query: 110 ADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA 166
++ CVHG C + C C+PGW GTNC D C S C NG C +T
Sbjct: 722 SNPCVHGACRDSLNGYKCDCDPGWSGTNC------DINNNECESN-PCVNGGTCKDMTSG 774
Query: 167 --CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC-DHVTG-ECRCPPGYTGAFCE 222
C C GF G C+ T N+C C N TC D V G +C C YTGA CE
Sbjct: 775 YVCTCREGFSGPNCQ------TNINECASN-PCLNQGTCIDDVAGYKCNCLLPYTGATCE 827
Query: 223 DLCPPGKHGPQCEQRCPCQNGGVCH----HVTGECSCPSGWMGTVCGQP----------- 267
+ P C PC+NGG C + + C CP+GW G C
Sbjct: 828 VVLAP------CAPS-PCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRH 880
Query: 268 --------------CPEGRFGKNCS---QECQ---CHNGGTCDAA--TGQCHCSPGYTGE 305
C G G+NC +C+ CHNGG+C T C C PG+ G
Sbjct: 881 GASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGT 940
Query: 306 RCQDE-------------------------CPVGTYGVLCAETC------QCVNGGKCYH 334
C+++ CP G G+ C C NGG C
Sbjct: 941 FCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCVD 1000
Query: 335 V--SGACLCEAGFAGERCEARL------------------------CPEGLYGIKCDK-- 366
S CLC GF G C+ + CP+G G C
Sbjct: 1001 GINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLV 1060
Query: 367 ----RCPCHLENTHSCHPMSGE--CACKPGWSGLYCNE---TCSPGFYGEACQQICSCQN 417
PC +N C + C C GW+GLYC+ +C + CQ+
Sbjct: 1061 HWCDSSPC--KNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH 1118
Query: 418 GADCDSV--TGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTC 473
G C T C C G+ G C ++ S C+N A C+ G SC C
Sbjct: 1119 GGLCVDAGNTHHCRCQAGYTGSYCEDL-------VDECSPSPCQNGATCTDYLGGYSCKC 1171
Query: 474 KAGWHGVDCS-------------------------IRCPSGTWGFGCNLTC--------- 499
AG+HGV+CS CP GT G C +
Sbjct: 1172 VAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEINVDDCNPPVDP 1231
Query: 500 -----QCLNGGACNTLDG--TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHP 552
+C N G C G +CTC PG+ GE+CE G + CD C
Sbjct: 1232 VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCE-----GDVNECLSNPCDARGTQNCVQ 1286
Query: 553 TTG--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG-----ICECAPG 605
HC C G +G C+SV + P CKNG +C+ IC+C G
Sbjct: 1287 RVNDFHCECRAGHTGRRCESVINGCKGKP-------CKNGGTCAVASNTARGFICKCPAG 1339
Query: 606 FRGTTCQ---RICSPGFYGHRCSQ--TCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVC 660
F G TC+ R C RC TC SGP + C CL FTG C
Sbjct: 1340 FEGATCENDARTCG----SLRCLNGGTC-----ISGPR---SPTCLCLGPFTGPECQFPA 1387
Query: 661 PSGRFGKNCAGICTCTNNGTCNPIDRS----CQC---------------YPGWIGSDCSQ 701
S G N C N GTC P S C C + G G D
Sbjct: 1388 SSPCLGGN-----PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPP 1442
Query: 702 PC-PPAHWGPNC-------IHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGK 753
P A P C + + C+N A C G+C CTQ Y
Sbjct: 1443 PLIEEACELPECQEDAGNKVCSLQCNNHA-CGWDGGDCSLNFNDPWKNCTQSLQCWKYFS 1501
Query: 754 DCALICQCQN------GADCDHISGQCT------CRTGFMGRHCEQKCPS 791
D QC + G DC GQC C+ F HC+Q C S
Sbjct: 1502 DGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNS 1551
Score = 200 bits (509), Expect = 6e-51
Identities = 187/661 (28%), Positives = 241/661 (36%), Gaps = 185/661 (27%)
Query: 274 GKNCSQECQ-CHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGG 330
G CSQ + C NGG C+AA G C C + G RCQD P C T C N G
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDPNP-------CLST-PCKNAG 72
Query: 331 KCYHVSG------ACLCEAGFAGERCEARLCPEGLYGIKCDKRC---PCHLENTHSCHPM 381
C+ V AC C GF+G C L D C PC N +C +
Sbjct: 73 TCHVVDRRGVADYACSCALGFSGPLCLTPL----------DNACLTNPC--RNGGTCDLL 120
Query: 382 S---GECACKPGWSGLYCNET------------------------CSPGFYGEACQQICS 414
+ +C C PGWSG C + C P F+G C+Q +
Sbjct: 121 TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN 180
Query: 415 --------CQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC 464
C++G C + G +C C G +C P + CS C+N C
Sbjct: 181 ECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPY------VPCSP-SPCQNGGTC 233
Query: 465 SP---VDGSCTCKAGWHGVDCSIR---CPSGTWGFGCNLTCQCLNGGACNTLDG----TC 514
P V C C G+ G +C CP C NGGAC +DG C
Sbjct: 234 RPTGDVTHECACLPGFTGQNCEENIDDCPGN----------NCKNGGAC--VDGVNTYNC 281
Query: 515 TCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHC---- 568
C P W G+ C + N C + CH T G +C C+ GW+G C
Sbjct: 282 RCPPEWTGQYCTEDVDECQLMPNA-----CQNGGTCHNTHGGYNCVCVNGWTGEDCSENI 336
Query: 569 -DSVCAEGRWGPNC-----SLPCYCKNGAS---CSPDDGICECAPGFRGTTCQR------ 613
D A G C S C C +G + C +D C P G+ C
Sbjct: 337 DDCASAACFHGATCHDRVASFYCECPHGRTGLLCHLNDA-CISNPCNEGSNCDTNPVNGK 395
Query: 614 ---ICSPGFYGHRCSQTCPQCVHSSGPCHH----ITGL----CDCLPGFTGALCN---EV 659
C G+ G CSQ +C + PC H I L C CL G+TG C
Sbjct: 396 AICTCPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNE 455
Query: 660 CPSGRFGKNCAGICTCTNNGTCNPIDR----SCQCYPGWIGSDCSQPCPPAHWGPNCIHT 715
C S C N+ TC +D+ C C PG+ G C P C+H
Sbjct: 456 CVSN----------PCQNDATC--LDQIGEFQCICMPGYEGVHCEVNTDECASSP-CLHN 502
Query: 716 CNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG--- 772
C + + +C+C G+TG C Y D C+NGA C + G
Sbjct: 503 GRCLD----KINEFQCECPTGFTGHLCQ-------YDVDECASTPCKNGAKC--LDGPNT 549
Query: 773 -QCTCRTGFMGRHCE---QKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARC 828
C C G+ G HCE +C YG C + T TC C PG+ G C
Sbjct: 550 YTCVCTEGYTGTHCEVDIDECDPDPCHYG-----SCKDGVA----TFTCLCRPGYTGHHC 600
Query: 829 D 829
+
Sbjct: 601 E 601
Score = 171 bits (434), Expect = 3e-42
Identities = 171/605 (28%), Positives = 215/605 (35%), Gaps = 134/605 (22%)
Query: 94 CCPGFYESGEMCVPHCADKCVHGRCIAPNTCQ---------CEPGWGGTNCSSACDGDHW 144
C PGF +G C H ++C C+ TCQ C G+ G NC + HW
Sbjct: 1009 CPPGF--TGSYC-QHDVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLV---HW 1062
Query: 145 GPHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCED---RCEQGTYGNDCHQRCQCQN 199
C S CKNG C C C +G+ G C+ CE CQ+
Sbjct: 1063 ---CDSS-PCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQH 1118
Query: 200 GATCDHV--TGECRCPPGYTGAFCEDL---CPPGKHGPQCEQRCPCQNGGVCHHVTGECS 254
G C T CRC GYTG++CEDL C P PCQNG C G S
Sbjct: 1119 GGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPS----------PCQNGATCTDYLGGYS 1168
Query: 255 CPSGWMGTVCGQPCPEGRFGKNCSQECQ------CHNGGTC--DAATGQCHCSPGYTGER 306
C C G G NCS+E C NGGTC T +C C G G
Sbjct: 1169 C-----------KCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVH 1217
Query: 307 CQ---DEC--PVGTYGVLCAETCQCVNGGKCYHVSG--ACLCEAGFAGERCEARLCPEGL 359
C+ D+C PV + + +C N G C G +C C GF GERCE +
Sbjct: 1218 CEINVDDCNPPVDP----VSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV--NEC 1271
Query: 360 YGIKCDKR-------------CPCHLENT-HSCHPMSGECACKPGWSGLYCNET------ 399
CD R C C +T C + C KP +G C
Sbjct: 1272 LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARG 1331
Query: 400 ----CSPGFYGEACQ---QICS---CQNGADCDS--VTGKCTCAPGFKGIDCSTPCPLGT 447
C GF G C+ + C C NG C S + C C F G +C P
Sbjct: 1332 FICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTGPECQFPASSPC 1391
Query: 448 YGINCSSRCGCKNDAVCSPVDGS----CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLN 503
G N C N C P S C C A ++G+ C I S G G ++ +
Sbjct: 1392 LGGN-----PCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIE 1446
Query: 504 GGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGW 563
AC + C + C L C + G + + C + D T +C +
Sbjct: 1447 -EACELPE----CQEDAGNKVCSLQCNNHACGWDGGD-CSLNFNDPWKNCTQSLQCWKYF 1500
Query: 564 SGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHR 623
S HCDS C N A C D C+ A G + C F
Sbjct: 1501 SDGHCDSQC----------------NSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGH 1544
Query: 624 CSQTC 628
C Q C
Sbjct: 1545 CDQGC 1549
Score = 55.5 bits (132), Expect = 3e-07
Identities = 41/133 (30%), Positives = 50/133 (37%), Gaps = 22/133 (16%)
Query: 709 GPNCIHTCN-CHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC 767
GP C C NG C A +G C G G + RC + L C+N C
Sbjct: 21 GPRCSQPGETCLNGGKCEAANGTEACVCG--GAFVGPRCQ----DPNPCLSTPCKNAGTC 74
Query: 768 DHISGQ------CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGT---CY 818
+ + C+C GF G C + CR N TCD +T T C
Sbjct: 75 HVVDRRGVADYACSCALGFSGPLCLTPLDNACLTNPCR------NGGTCDLLTLTEYKCR 128
Query: 819 CSPGWKGARCDQA 831
C PGW G C QA
Sbjct: 129 CPPGWSGKSCQQA 141
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 281 bits (720), Expect = 2e-75
Identities = 235/776 (30%), Positives = 286/776 (36%), Gaps = 227/776 (29%)
Query: 94 CCPGFYESGEMCVPHCADKCVHG-----RCIAPNTCQCEPGWGGTNCSSACDGD---HWG 145
CCP ++G +HG RC TC CEPGWGG CS D +
Sbjct: 125 CCPASAQAGTGQTDVRTLCSLHGVFDLSRC----TCSCEPGWGGPTCSDPTDAEIPPSSP 180
Query: 146 PHCTSRC--QCKNGALCNPITGACHCAAGFRGWRC-----------EDRCEQGTY----- 187
P + C C + C + G C C G+ G C RC QG
Sbjct: 181 PSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAG 238
Query: 188 --GNDCHQRC---QCQNGATCDHVTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPCQ 241
G DC QR C C+ G C C PGYTG C CP G C QR C+
Sbjct: 239 FSGPDCSQRSCPRGCSQRGRCEG--GRCVCDPGYTGDDCGMRSCPRG-----CSQRGRCE 291
Query: 242 NGGVCHHVTGECSCPSGWMGTVCG-QPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
NG C C G+ G CG + CP G CSQ +C +G +C C P
Sbjct: 292 NG--------RCVCNPGYTGEDCGVRSCPRG-----CSQRGRCKDG--------RCVCDP 330
Query: 301 GYTGERCQDE-CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGL 359
GYTGE C CP C GG+C V G C+C G+ GE C R CP
Sbjct: 331 GYTGEDCGTRSCP-----------WDCGEGGRC--VDGRCVCWPGYTGEDCSTRTCPRD- 376
Query: 360 YGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419
C R C GEC C G+SG C PG C Q C++G
Sbjct: 377 ----CRGRGRCE----------DGECICDTGYSGDDCGVRSCPG----DCNQRGRCEDG- 417
Query: 420 DCDSVTGKCTCAPGFKGIDC-STPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWH 478
+C C PG+ G DC S CP +C R C+N G C C AG+
Sbjct: 418 -------RCVCWPGYTGTDCGSRACPR-----DCRGRGRCEN--------GVCVCNAGYS 457
Query: 479 GVDCSIR-CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLN 537
G DC +R CP C G C + G C C PG+ G C G
Sbjct: 458 GEDCGVRSCPG-----------DCRGRGRCES--GRCMCWPGYTGRDCGTRACPG----- 499
Query: 538 CAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS------------------VCAEGRWGP 579
DC C G C C PG++G C S VC G G
Sbjct: 500 -----DCRGRGRC--VDGRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGE 552
Query: 580 NCSL---PCYCKNGASCSPDDGICECAPGFRGTTCQR------------------ICSPG 618
+CS P C+ C DG C C G+ G C IC G
Sbjct: 553 DCSTRSCPGGCRGRGQCL--DGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEG 610
Query: 619 FYGHRCS-QTCPQCVHSSGPCHHITGLCDCLPGFTGALC-NEVCPSGRFGKNCAGICTCT 676
+ CS +TCP H G C G C C PG+TG C +CP+ C
Sbjct: 611 YVSEDCSIRTCPSNCHGRGRCEE--GRCLCDPGYTGPTCATRMCPAD-----------CR 657
Query: 677 NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPG 736
G C + C C+ G+ G DC Q PPA P C C A G+C C G
Sbjct: 658 GRGRC--VQGVCLCHVGYGGEDCGQEEPPASACPG-----GCGPRELCRA--GQCVCVEG 708
Query: 737 WTGLYCT-QRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPS 791
+ G C Q CP C+ +C G C C+ G+ G C ++ P+
Sbjct: 709 FRGPDCAIQTCP-----------GDCRGRGECH--DGSCVCKDGYAGEDCGEEVPT 751
Score = 241 bits (616), Expect = 2e-63
Identities = 197/663 (29%), Positives = 245/663 (36%), Gaps = 188/663 (28%)
Query: 217 TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPC-----PEG 271
TG C G Q + R C GV CSC GW G C P P
Sbjct: 122 TGGCCPASAQAGTG--QTDVRTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSS 179
Query: 272 RFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQ-DECPVGTYGVLCAETCQCVNGG 330
+ S C++ G C G+C C PGYTG C CP C G
Sbjct: 180 PPSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSCGWPSCPG-----------DCQGRG 226
Query: 331 KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPG 390
+C V G C+C AGF+G C R CP G C +R C G C C PG
Sbjct: 227 RC--VQGVCVCRAGFSGPDCSQRSCPRG-----CSQRGRCE----------GGRCVCDPG 269
Query: 391 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST-PCPLGTYG 449
++G C P C Q C+NG +C C PG+ G DC CP G
Sbjct: 270 YTGDDCGMRSCP----RGCSQRGRCENG--------RCVCNPGYTGEDCGVRSCPRG--- 314
Query: 450 INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR-CPSGTWGFGCNLTCQCLNGGACN 508
CS R CK DG C C G+ G DC R CP W C GG C
Sbjct: 315 --CSQRGRCK--------DGRCVCDPGYTGEDCGTRSCP---W--------DCGEGGRC- 352
Query: 509 TLDGTCTCAPGWRGEKC------------------ELPCQDGTYGLNCAERC---DCSHA 547
+DG C C PG+ GE C E C G G +C R DC+
Sbjct: 353 -VDGRCVCWPGYTGEDCSTRTCPRDCRGRGRCEDGECICDTGYSGDDCGVRSCPGDCNQR 411
Query: 548 DGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFR 607
C G C C PG++G C S P C+ C ++G+C C G+
Sbjct: 412 GRCED--GRCVCWPGYTGTDCGSRAC----------PRDCRGRGRC--ENGVCVCNAGYS 457
Query: 608 GTTC------------------QRICSPGFYGHRC-SQTCPQCVHSSGPCHHITGLCDCL 648
G C + +C PG+ G C ++ CP G C + G C C
Sbjct: 458 GEDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTRACPGDCRGRGRC--VDGRCVCN 515
Query: 649 PGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCS-QPCPPAH 707
PGFTG C + C G C +G C D C C G+ G DCS + CP
Sbjct: 516 PGFTGEDCGS--------RRCPG--DCRGHGLCE--DGVCVCDAGYSGEDCSTRSCPGG- 562
Query: 708 WGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYC-TQRCPLGFYGKDCALICQCQNGAD 766
C C DG C C G++G C ++CP DC+ CQ+G
Sbjct: 563 ----------CRGRGQC--LDGRCVCEDGYSGEDCGVRQCP-----NDCSQHGVCQDGV- 604
Query: 767 CDHISGQCTCRTGFMGRHCE-QKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKG 825
C C G++ C + CPS +G G C+ G C C PG+ G
Sbjct: 605 -------CICWEGYVSEDCSIRTCPSNCHGRG-----------RCEE--GRCLCDPGYTG 644
Query: 826 ARC 828
C
Sbjct: 645 PTC 647
Score = 42.4 bits (98), Expect = 0.003
Identities = 28/106 (26%), Positives = 36/106 (33%), Gaps = 21/106 (19%)
Query: 731 CKCTPGWTGLYCTQRC-----PLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHC 785
C C PGW G C+ P + C + C + G+C C G+ G C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRC--VRGRCVCFPGYTGPSC 213
Query: 786 E-QKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
CP DC C + G C C G+ G C Q
Sbjct: 214 GWPSCPG-----------DCQGRGRC--VQGVCVCRAGFSGPDCSQ 246
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 276 bits (705), Expect = 1e-73
Identities = 147/422 (34%), Positives = 186/422 (44%), Gaps = 60/422 (14%)
Query: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
S + + C G++ D P+ C C+ D VC G C CK G+ G C
Sbjct: 34 SPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHC 86
Query: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542
S RCP WG C +C C G C G C C G +CE PC G +G RC
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-----RC 141
Query: 543 DCSHADGCHPTTGHCRCLPGW-------------SGVHCDS-----VCAEGRWGPNCSLP 584
D P TG C C PGW + C+ VC G WG CS
Sbjct: 142 D--------PATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
Query: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
C C +G+ C D G C C PG+ G CQ+ C +CV G C +G
Sbjct: 194 CNC-HGSPCEQDSGRCACRPGWWGPECQQQC--------------ECVR--GRCSAASGE 236
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSCQ-CYPGWIGSDCSQP 702
C C PGF GA C CP+G G CA C C +N C+P SC+ C PGW G+ C QP
Sbjct: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP 296
Query: 703 CPPAHWGPNCIHTC-NCHNGAFCSAYDGEC-KCTPGWTGLYCTQRCPLGFYGKDCALICQ 760
C P +G +C C +C +G C G C +C PGW G C CP G +G+DC C
Sbjct: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCP 356
Query: 761 CQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCS 820
CD ++G C C G+ G C CP+G +G C C+C C ++G+C
Sbjct: 357 TCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC-PEGLCHPVSGSCQPG 415
Query: 821 PG 822
G
Sbjct: 416 SG 417
Score = 272 bits (696), Expect = 1e-72
Identities = 144/420 (34%), Positives = 186/420 (44%), Gaps = 60/420 (14%)
Query: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST 441
S E C GW ++ C+ C+ +CQ C G C C PGF G CS+
Sbjct: 36 SAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSS 88
Query: 442 PCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQC 501
CP +G +C C C C P G+C C+A WG C C C
Sbjct: 89 RCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCAC 135
Query: 502 LNGGACNTLDGTCTCAPGWRGEKCELPCQ------------------DGTYGLNCAERCD 543
G C+ G C C PGW C PCQ G +G C+ RC+
Sbjct: 136 GPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN 195
Query: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
C H C +G C C PGW WGP C C C G CS G C C
Sbjct: 196 C-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRGR-CSAASGECTCP 240
Query: 604 PGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALCNEVCPS 662
PGFRG C+ C G +G +C+ +C +C H+ PC TG C+ C PG+ G C + C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNE-PCSPDTGSCESCEPGWNGTQCQQPCLP 299
Query: 663 GRFGKNCAGICT-CTNNGTCNPIDRSCQ-CYPGWIGSDCSQPCPPAHWGPNCIHTC-NCH 719
G FG++C C C + C P CQ C PGW+G C PCP +G +C TC C
Sbjct: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCV 359
Query: 720 NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTG 779
G+ C G+C C+ G+ G C CP GF+G +C++ C+C G C +SG C +G
Sbjct: 360 QGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSG 417
Score = 271 bits (693), Expect = 3e-72
Identities = 146/412 (35%), Positives = 192/412 (46%), Gaps = 55/412 (13%)
Query: 93 QCCPGFYESGEMC-VPHCA--DKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148
QCC G+ + + C +P C D C C+ P C+C+PG+ G +CSS C G +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 149 TSRCQCKNGALCNPITGACHCAAGFRGWRCE-----------------DRCEQGTYGNDC 191
C C C P TGAC C A G RCE CE G + + C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 192 HQRCQCQNGAT-CDHVTGECRCPPGYTGAFC----------------EDLCPPGKHGPQC 234
+ CQC A C+ TG C C PG+ G C C PG GP+C
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPEC 219
Query: 235 EQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQEC-QCHNGGTCDAAT 293
+Q+C C G C +GEC+CP G+ G C PCP G G C+ C +C + C T
Sbjct: 220 QQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDT 278
Query: 294 GQCH-CSPGYTGERCQDECPVGTYGVLCAETC-QCVNGGKCYHVSGAC-LCEAGFAGERC 350
G C C PG+ G +CQ C GT+G C + C C +G C +G C C+ G+ G RC
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRC 338
Query: 351 EARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ 410
E CP G +G C CP ++ SC ++G+C C G+ G CN +C GF+G C
Sbjct: 339 EDP-CPTGTFGEDCGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCS 395
Query: 411 QICSCQNGADCDSVTGKCTCAPGFKGIDCS------TPCPLGTYGINCSSRC 456
C C G C V+G +C PG D + P L G+ C + C
Sbjct: 396 VPCECPEGL-CHPVSG--SCQPGSGSRDTALIAGSLVPLLLLFLGLACCACC 444
Score = 269 bits (688), Expect = 1e-71
Identities = 142/398 (35%), Positives = 181/398 (45%), Gaps = 50/398 (12%)
Query: 250 TGECSCPSGWM--GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
+ E C +GW C P EG C C G C C PG+ G C
Sbjct: 36 SAELQCCAGWRQKDQECTIPICEGPDA--------CQKDEVC-VKPGLCRCKPGFFGAHC 86
Query: 308 QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL------------- 354
CP +G C E+C C G+C +GAC C+A G RCE
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG 146
Query: 355 ---CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCS---------- 401
C G + C + C C+ C +G C CKPGW G C+ C+
Sbjct: 147 VCHCEPGWWSSTCRRPCQCNTAAAR-CEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDS 205
Query: 402 ------PGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 455
PG++G CQQ C C G C + +G+CTC PGF+G C PCP G++G+ C+
Sbjct: 206 GRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 456 CG-CKNDAVCSPVDGSC-TCKAGWHGVDCSIRCPSGTWGFGCNLTC-QCLNGGACNTLDG 512
CG CK++ CSP GSC +C+ GW+G C C GT+G C C C +G AC G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 513 TCT-CAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSV 571
C C PGW G +CE PC GT+G +C C C TG C C G+ G C++
Sbjct: 325 HCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS 384
Query: 572 CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGT 609
C G G NCS+PC C G C P G C+ G R T
Sbjct: 385 CPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSGSRDT 421
Score = 181 bits (459), Expect = 4e-45
Identities = 94/275 (34%), Positives = 119/275 (43%), Gaps = 56/275 (20%)
Query: 581 CSLPCYCKNGASCSPDD-----GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
C++P C+ +C D+ G+C C PGF G C C ++G C ++CP H
Sbjct: 52 CTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCP--CHPH 108
Query: 636 GPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWI 695
G C TG C C + R+G C C C +G C+P C C PGW
Sbjct: 109 GQCEPATGACQC-------------QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWW 155
Query: 696 GSDCSQPCP------------------PAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGW 737
S C +PC P WG C CNCH G+ C G C C PGW
Sbjct: 156 SSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCH-GSPCEQDSGRCACRPGW 214
Query: 738 TGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYG 797
G C Q+C +C G C SG+CTC GF G CE CP+G++G
Sbjct: 215 WGPECQQQC-------------ECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQ 260
Query: 798 CRQICD-CLNNSTCDHITGTCY-CSPGWKGARCDQ 830
C C C +N C TG+C C PGW G +C Q
Sbjct: 261 CAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
Score = 109 bits (272), Expect = 2e-23
Identities = 59/200 (29%), Positives = 81/200 (40%), Gaps = 33/200 (16%)
Query: 669 CAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYD 728
C G C + C C+C PG+ G+ CS CP +WGP+C +C CH C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
Query: 729 GECKCTPGWTGLYCTQRCPLGFYGK-----------------DCALICQCQNGAD-CDHI 770
G C+C G C C G +G+ C CQC A C+
Sbjct: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA 175
Query: 771 SGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
+G C C+ G+ GR C +C +C + S C+ +G C C PGW G C Q
Sbjct: 176 TGACVCKPGWWGRRCSFRC-------------NC-HGSPCEQDSGRCACRPGWWGPECQQ 221
Query: 831 AGVIIVGNLNSLSRTSTALP 850
+ G ++ S T P
Sbjct: 222 QCECVRGRCSAASGECTCPP 241
Score = 67.4 bits (163), Expect = 7e-11
Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 745 RCPLGFYGKD--CAL-ICQCQNGADCDHIS---GQCTCRTGFMGRHCEQKCPSGTYGYGC 798
+C G+ KD C + IC+ + D + G C C+ GF G HC +CP +G C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 799 RQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
R+ C C + C+ TG C C GARC+
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCE 130
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 276 bits (705), Expect = 1e-73
Identities = 147/422 (34%), Positives = 186/422 (44%), Gaps = 60/422 (14%)
Query: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
S + + C G++ D P+ C C+ D VC G C CK G+ G C
Sbjct: 34 SPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHC 86
Query: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542
S RCP WG C +C C G C G C C G +CE PC G +G RC
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-----RC 141
Query: 543 DCSHADGCHPTTGHCRCLPGW-------------SGVHCDS-----VCAEGRWGPNCSLP 584
D P TG C C PGW + C+ VC G WG CS
Sbjct: 142 D--------PATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
Query: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
C C +G+ C D G C C PG+ G CQ+ C +CV G C +G
Sbjct: 194 CNC-HGSPCEQDSGRCACRPGWWGPECQQQC--------------ECVR--GRCSAASGE 236
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSCQ-CYPGWIGSDCSQP 702
C C PGF GA C CP+G G CA C C +N C+P SC+ C PGW G+ C QP
Sbjct: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP 296
Query: 703 CPPAHWGPNCIHTC-NCHNGAFCSAYDGEC-KCTPGWTGLYCTQRCPLGFYGKDCALICQ 760
C P +G +C C +C +G C G C +C PGW G C CP G +G+DC C
Sbjct: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCP 356
Query: 761 CQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCS 820
CD ++G C C G+ G C CP+G +G C C+C C ++G+C
Sbjct: 357 TCVQGSCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCEC-PEGLCHPVSGSCQPG 415
Query: 821 PG 822
G
Sbjct: 416 SG 417
Score = 272 bits (696), Expect = 1e-72
Identities = 144/420 (34%), Positives = 186/420 (44%), Gaps = 60/420 (14%)
Query: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST 441
S E C GW ++ C+ C+ +CQ C G C C PGF G CS+
Sbjct: 36 SAELQCCAGWRQK--DQECTIPI----CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSS 88
Query: 442 PCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQC 501
CP +G +C C C C P G+C C+A WG C C C
Sbjct: 89 RCPGQYWGPDCRESCPCHPHGQCEPATGACQCQAD-------------RWGARCEFPCAC 135
Query: 502 LNGGACNTLDGTCTCAPGWRGEKCELPCQ------------------DGTYGLNCAERCD 543
G C+ G C C PGW C PCQ G +G C+ RC+
Sbjct: 136 GPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCN 195
Query: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
C H C +G C C PGW WGP C C C G CS G C C
Sbjct: 196 C-HGSPCEQDSGRCACRPGW-------------WGPECQQQCECVRGR-CSAASGECTCP 240
Query: 604 PGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALCNEVCPS 662
PGFRG C+ C G +G +C+ +C +C H+ PC TG C+ C PG+ G C + C
Sbjct: 241 PGFRGARCELPCPAGSHGVQCAHSCGRCKHNE-PCSPDTGSCESCEPGWNGTQCQQPCLP 299
Query: 663 GRFGKNCAGICT-CTNNGTCNPIDRSCQ-CYPGWIGSDCSQPCPPAHWGPNCIHTC-NCH 719
G FG++C C C + C P CQ C PGW+G C PCP +G +C TC C
Sbjct: 300 GTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCV 359
Query: 720 NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTG 779
G+ C G+C C+ G+ G C CP GF+G +C++ C+C G C +SG C +G
Sbjct: 360 QGS-CDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSG 417
Score = 271 bits (693), Expect = 3e-72
Identities = 146/412 (35%), Positives = 192/412 (46%), Gaps = 55/412 (13%)
Query: 93 QCCPGFYESGEMC-VPHCA--DKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148
QCC G+ + + C +P C D C C+ P C+C+PG+ G +CSS C G +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 149 TSRCQCKNGALCNPITGACHCAAGFRGWRCE-----------------DRCEQGTYGNDC 191
C C C P TGAC C A G RCE CE G + + C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 192 HQRCQCQNGAT-CDHVTGECRCPPGYTGAFC----------------EDLCPPGKHGPQC 234
+ CQC A C+ TG C C PG+ G C C PG GP+C
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPEC 219
Query: 235 EQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQEC-QCHNGGTCDAAT 293
+Q+C C G C +GEC+CP G+ G C PCP G G C+ C +C + C T
Sbjct: 220 QQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDT 278
Query: 294 GQCH-CSPGYTGERCQDECPVGTYGVLCAETC-QCVNGGKCYHVSGAC-LCEAGFAGERC 350
G C C PG+ G +CQ C GT+G C + C C +G C +G C C+ G+ G RC
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCDPGWLGPRC 338
Query: 351 EARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ 410
E CP G +G C CP ++ SC ++G+C C G+ G CN +C GF+G C
Sbjct: 339 EDP-CPTGTFGEDCGSTCPTCVQG--SCDTVTGDCVCSAGYWGPSCNASCPAGFHGNNCS 395
Query: 411 QICSCQNGADCDSVTGKCTCAPGFKGIDCS------TPCPLGTYGINCSSRC 456
C C G C V+G +C PG D + P L G+ C + C
Sbjct: 396 VPCECPEGL-CHPVSG--SCQPGSGSRDTALIAGSLVPLLLLFLGLACCACC 444
Score = 269 bits (688), Expect = 1e-71
Identities = 142/398 (35%), Positives = 181/398 (45%), Gaps = 50/398 (12%)
Query: 250 TGECSCPSGWM--GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
+ E C +GW C P EG C C G C C PG+ G C
Sbjct: 36 SAELQCCAGWRQKDQECTIPICEGPDA--------CQKDEVC-VKPGLCRCKPGFFGAHC 86
Query: 308 QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL------------- 354
CP +G C E+C C G+C +GAC C+A G RCE
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG 146
Query: 355 ---CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCS---------- 401
C G + C + C C+ C +G C CKPGW G C+ C+
Sbjct: 147 VCHCEPGWWSSTCRRPCQCNTAAAR-CEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDS 205
Query: 402 ------PGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 455
PG++G CQQ C C G C + +G+CTC PGF+G C PCP G++G+ C+
Sbjct: 206 GRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 456 CG-CKNDAVCSPVDGSC-TCKAGWHGVDCSIRCPSGTWGFGCNLTC-QCLNGGACNTLDG 512
CG CK++ CSP GSC +C+ GW+G C C GT+G C C C +G AC G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 513 TCT-CAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSV 571
C C PGW G +CE PC GT+G +C C C TG C C G+ G C++
Sbjct: 325 HCQRCDPGWLGPRCEDPCPTGTFGEDCGSTCPTCVQGSCDTVTGDCVCSAGYWGPSCNAS 384
Query: 572 CAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGT 609
C G G NCS+PC C G C P G C+ G R T
Sbjct: 385 CPAGFHGNNCSVPCECPEGL-CHPVSGSCQPGSGSRDT 421
Score = 181 bits (459), Expect = 4e-45
Identities = 94/275 (34%), Positives = 119/275 (43%), Gaps = 56/275 (20%)
Query: 581 CSLPCYCKNGASCSPDD-----GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
C++P C+ +C D+ G+C C PGF G C C ++G C ++CP H
Sbjct: 52 CTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCP--CHPH 108
Query: 636 GPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWI 695
G C TG C C + R+G C C C +G C+P C C PGW
Sbjct: 109 GQCEPATGACQC-------------QADRWGARCEFPCACGPHGRCDPATGVCHCEPGWW 155
Query: 696 GSDCSQPCP------------------PAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGW 737
S C +PC P WG C CNCH G+ C G C C PGW
Sbjct: 156 SSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCH-GSPCEQDSGRCACRPGW 214
Query: 738 TGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYG 797
G C Q+C +C G C SG+CTC GF G CE CP+G++G
Sbjct: 215 WGPECQQQC-------------ECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQ 260
Query: 798 CRQICD-CLNNSTCDHITGTCY-CSPGWKGARCDQ 830
C C C +N C TG+C C PGW G +C Q
Sbjct: 261 CAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
Score = 109 bits (272), Expect = 2e-23
Identities = 59/200 (29%), Positives = 81/200 (40%), Gaps = 33/200 (16%)
Query: 669 CAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYD 728
C G C + C C+C PG+ G+ CS CP +WGP+C +C CH C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
Query: 729 GECKCTPGWTGLYCTQRCPLGFYGK-----------------DCALICQCQNGAD-CDHI 770
G C+C G C C G +G+ C CQC A C+
Sbjct: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA 175
Query: 771 SGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
+G C C+ G+ GR C +C +C + S C+ +G C C PGW G C Q
Sbjct: 176 TGACVCKPGWWGRRCSFRC-------------NC-HGSPCEQDSGRCACRPGWWGPECQQ 221
Query: 831 AGVIIVGNLNSLSRTSTALP 850
+ G ++ S T P
Sbjct: 222 QCECVRGRCSAASGECTCPP 241
Score = 67.4 bits (163), Expect = 7e-11
Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 6/91 (6%)
Query: 745 RCPLGFYGKD--CAL-ICQCQNGADCDHIS---GQCTCRTGFMGRHCEQKCPSGTYGYGC 798
+C G+ KD C + IC+ + D + G C C+ GF G HC +CP +G C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 799 RQICDCLNNSTCDHITGTCYCSPGWKGARCD 829
R+ C C + C+ TG C C GARC+
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCE 130
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 275 bits (704), Expect = 1e-73
Identities = 143/401 (35%), Positives = 180/401 (44%), Gaps = 54/401 (13%)
Query: 94 CCPGFYESGEMC---VPHCADKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT 149
CC G+ + G+ C V C C+ P C+C G+ G NC + C WGP C
Sbjct: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
Query: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
C C C +TG C C A G RCE CQCQ+G TC +G
Sbjct: 124 ELCSCHPHGQCEDVTGQCTCHARRWGARCE-------------HACQCQHG-TCHPRSGA 169
Query: 210 CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCP 269
CRC PG+ GA QC C C C TG C C +GW G C C
Sbjct: 170 CRCEPGWWGA-------------QCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCA 216
Query: 270 ----------------EGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPV 313
E FG C + CQC G C G C C PGY G+ C++ CP
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 314 GTYGVLCAETC-QCVNGGKCYHVSGACL-CEAGFAGERCEARLCPEGLYGIKCDKRCPCH 371
G YG+ C C QC C G CL CE G+ G +C+ + C G YG C RCP
Sbjct: 276 GFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCD-QPCATGFYGEGCSHRCP-P 333
Query: 372 LENTHSCHPMSGECA-CKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTC 430
+ H+C+ ++G+C C GW G C CS G YGE C +C+ CD +G+C C
Sbjct: 334 CRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLC 393
Query: 431 APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471
+PG G C+ CP G +G +C+ C C D C PV G+C
Sbjct: 394 SPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGAC 433
Score = 274 bits (701), Expect = 3e-73
Identities = 141/412 (34%), Positives = 178/412 (43%), Gaps = 62/412 (15%)
Query: 429 TCAPGFK--GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC 486
TC G++ G +C C C + VC G C C+ G+ G +C +C
Sbjct: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 487 PSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
P WG C C C G C + G CTC G +CE CQ C H
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------------CQH 160
Query: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF 606
CHP +G CRC PGW WG C+ CYC + C P G C C G+
Sbjct: 161 GT-CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW 206
Query: 607 RGTTCQRICSPGF----------------YGHRCSQTCPQCVHSSGPCHHITGLCDCLPG 650
G +C C+ +G RC + C QC G CH + G C C PG
Sbjct: 207 WGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYC-QCFR--GRCHPVDGTCACEPG 263
Query: 651 FTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSC-QCYPGWIGSDCSQPCPPAHW 708
+ G C E CP+G +G C C C C + C C PGW G+ C QPC +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 709 GPNCIHTCN-CHNGAFCSAYDGEC-KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD 766
G C H C C +G C+ G+C +C GW G C +C G YG+DCA +C
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
Query: 767 CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCY 818
CD SG+C C G G HC CP G +G C Q C C + TCD +TG C+
Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGACH 434
Score = 233 bits (593), Expect = 1e-60
Identities = 122/375 (32%), Positives = 157/375 (41%), Gaps = 46/375 (12%)
Query: 399 TCSPGF--YGEACQQICSCQNGADCDSVT-----GKCTCAPGFKGIDCSTPCPLGTYGIN 451
TC G+ G+ C I C+ + C G+C C G+ G +C T CP +G +
Sbjct: 63 TCCAGWRQQGDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD 121
Query: 452 CSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC----------------SIRCPSGTWGFGC 495
C C C C V G CTC A G C + RC G WG C
Sbjct: 122 CKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQC 181
Query: 496 NLTCQCLNGGACNTLDGTCTCAPGWRGEKCE----------------LPCQDGTYGLNCA 539
C C C+ G C C GW G C C++ T+G C
Sbjct: 182 ASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCD 241
Query: 540 ERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC-YCKNGASCSPDDG 598
C C CHP G C C PG+ G +C C G +G C C CK C+ +G
Sbjct: 242 RYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
Query: 599 IC-ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALC 656
C C PG+ GT C + C+ GFYG CS CP C C+H+TG C C G+ G C
Sbjct: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC-RDGHACNHVTGKCTRCNAGWIGDRC 359
Query: 657 NEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
C +G +G++CA +C +G C+ C C PG G C+ CPP G +C C
Sbjct: 360 ETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQAC 419
Query: 717 NCHNGAFCSAYDGEC 731
+CH C G C
Sbjct: 420 SCHEDT-CDPVTGAC 433
Score = 164 bits (416), Expect = 3e-40
Identities = 89/290 (30%), Positives = 117/290 (40%), Gaps = 55/290 (18%)
Query: 565 GVHCDSVCAEGRW-GPNCSLPCYCKNGASCSPDD-----GICECAPGFRGTTCQRICSPG 618
G + CA R G C + C+ ++CS ++ G C C G+ G C C
Sbjct: 58 GSQVPTCCAGWRQQGDECGI-AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
Query: 619 FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNN 678
F+G C + C H G C +TG C C + R+G C C C +
Sbjct: 117 FWGPDCKELCS--CHPHGQCEDVTGQC-------------TCHARRWGARCEHACQC-QH 160
Query: 679 GTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
GTC+P +C+C PGW WG C C C + C G C C GW
Sbjct: 161 GTCHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGWW 207
Query: 739 GLYCTQRCPLGF----------------YGKDCALICQCQNGADCDHISGQCTCRTGFMG 782
G C +C +G C CQC G C + G C C G+ G
Sbjct: 208 GRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRG 266
Query: 783 RHCEQKCPSGTYGYGCRQIC-DCLNNSTCDHITGTCY-CSPGWKGARCDQ 830
++C + CP+G YG GCR+ C C C G C C PGW G +CDQ
Sbjct: 267 KYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ 316
Score = 158 bits (399), Expect = 3e-38
Identities = 80/201 (39%), Positives = 96/201 (47%), Gaps = 8/201 (3%)
Query: 102 GEMCVPHCADKCVHGRCI-APNTCQCEPGWGGTNCSSACDGDHWGPHCTSRC-QCKNGAL 159
G C +C +C GRC TC CEPG+ G C C +G C RC QCK
Sbjct: 237 GARCDRYC--QCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQP 294
Query: 160 CNPITGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQRCQ-CQNGATCDHVTGEC-RCPPGY 216
C G C C G+ G +C+ C G YG C RC C++G C+HVTG+C RC G+
Sbjct: 295 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGW 354
Query: 217 TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKN 276
G CE C G +G C C G C +G C C G G C CP G G +
Sbjct: 355 IGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
Query: 277 CSQECQCHNGGTCDAATGQCH 297
C+Q C CH TCD TG CH
Sbjct: 415 CAQACSCHED-TCDPVTGACH 434
Score = 139 bits (350), Expect = 2e-32
Identities = 77/211 (36%), Positives = 93/211 (44%), Gaps = 20/211 (9%)
Query: 53 DQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADK 112
++ + C F+ H V A G + Y R+ C GFY G C +
Sbjct: 233 ERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREP-CPAGFYGLG------CRRR 285
Query: 113 CVHGRCIAPNTCQ--------CEPGWGGTNCSSACDGDHWGPHCTSRCQ-CKNGALCNPI 163
C G+C C CEPGW GT C C +G C+ RC C++G CN +
Sbjct: 286 C--GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHV 343
Query: 164 TGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE 222
TG C C AG+ G RCE +C GTYG DC C CD +G C C PG G C
Sbjct: 344 TGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN 403
Query: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGEC 253
CPPG HG C Q C C C VTG C
Sbjct: 404 VTCPPGLHGADCAQACSCHE-DTCDPVTGAC 433
Score = 89.0 bits (219), Expect = 2e-17
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 19/119 (15%)
Query: 718 CHNGAFCSAYD-----GECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG 772
C + CS + GEC+C G+ G C +CP F+G DC +C C C+ ++G
Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
Query: 773 QCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
QCTC G CE C + TC +G C C PGW GA+C A
Sbjct: 140 QCTCHARRWGARCEHACQC--------------QHGTCHPRSGACRCEPGWWGAQCASA 184
Score = 68.9 bits (167), Expect = 3e-11
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 752 GKDCALICQCQNGADCDHIS-----GQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN 806
G +C I C+ + C G+C CR G+ G +C+ KCP +G C+++C C
Sbjct: 72 GDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
Query: 807 NSTCDHITGTCYCSPGWKGARCDQA 831
+ C+ +TG C C GARC+ A
Sbjct: 131 HGQCEDVTGQCTCHARRWGARCEHA 155
Score = 57.4 bits (137), Expect = 8e-08
Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRC-IAPNTCQCEPGWGGTNCSSACDGDHWGPH 147
R +++C G Y GE C CAD C G C C C PG G +C+ C G
Sbjct: 358 RCETKCSNGTY--GEDCAFVCAD-CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
Query: 148 CTSRCQCKNGALCNPITGACH 168
C C C C+P+TGACH
Sbjct: 415 CAQACSCHEDT-CDPVTGACH 434
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 275 bits (704), Expect = 1e-73
Identities = 143/401 (35%), Positives = 180/401 (44%), Gaps = 54/401 (13%)
Query: 94 CCPGFYESGEMC---VPHCADKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT 149
CC G+ + G+ C V C C+ P C+C G+ G NC + C WGP C
Sbjct: 64 CCAGWRQQGDECGIAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCK 123
Query: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
C C C +TG C C A G RCE CQCQ+G TC +G
Sbjct: 124 ELCSCHPHGQCEDVTGQCTCHARRWGARCE-------------HACQCQHG-TCHPRSGA 169
Query: 210 CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCP 269
CRC PG+ GA QC C C C TG C C +GW G C C
Sbjct: 170 CRCEPGWWGA-------------QCASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCA 216
Query: 270 ----------------EGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPV 313
E FG C + CQC G C G C C PGY G+ C++ CP
Sbjct: 217 CNSSPCEQQSGRCQCRERTFGARCDRYCQCFRG-RCHPVDGTCACEPGYRGKYCREPCPA 275
Query: 314 GTYGVLCAETC-QCVNGGKCYHVSGACL-CEAGFAGERCEARLCPEGLYGIKCDKRCPCH 371
G YG+ C C QC C G CL CE G+ G +C+ + C G YG C RCP
Sbjct: 276 GFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCD-QPCATGFYGEGCSHRCP-P 333
Query: 372 LENTHSCHPMSGECA-CKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTC 430
+ H+C+ ++G+C C GW G C CS G YGE C +C+ CD +G+C C
Sbjct: 334 CRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLC 393
Query: 431 APGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSC 471
+PG G C+ CP G +G +C+ C C D C PV G+C
Sbjct: 394 SPGVHGPHCNVTCPPGLHGADCAQACSCHED-TCDPVTGAC 433
Score = 274 bits (701), Expect = 3e-73
Identities = 141/412 (34%), Positives = 178/412 (43%), Gaps = 62/412 (15%)
Query: 429 TCAPGFK--GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC 486
TC G++ G +C C C + VC G C C+ G+ G +C +C
Sbjct: 63 TCCAGWRQQGDECGIAV--------CEGNSTCSENEVCVR-PGECRCRHGYFGANCDTKC 113
Query: 487 PSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
P WG C C C G C + G CTC G +CE CQ C H
Sbjct: 114 PRQFWGPDCKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQ-------------CQH 160
Query: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF 606
CHP +G CRC PGW WG C+ CYC + C P G C C G+
Sbjct: 161 GT-CHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGW 206
Query: 607 RGTTCQRICSPGF----------------YGHRCSQTCPQCVHSSGPCHHITGLCDCLPG 650
G +C C+ +G RC + C QC G CH + G C C PG
Sbjct: 207 WGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYC-QCFR--GRCHPVDGTCACEPG 263
Query: 651 FTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSC-QCYPGWIGSDCSQPCPPAHW 708
+ G C E CP+G +G C C C C + C C PGW G+ C QPC +
Sbjct: 264 YRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFY 323
Query: 709 GPNCIHTCN-CHNGAFCSAYDGEC-KCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD 766
G C H C C +G C+ G+C +C GW G C +C G YG+DCA +C
Sbjct: 324 GEGCSHRCPPCRDGHACNHVTGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGH 383
Query: 767 CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCY 818
CD SG+C C G G HC CP G +G C Q C C + TCD +TG C+
Sbjct: 384 CDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQACSC-HEDTCDPVTGACH 434
Score = 233 bits (593), Expect = 1e-60
Identities = 122/375 (32%), Positives = 157/375 (41%), Gaps = 46/375 (12%)
Query: 399 TCSPGF--YGEACQQICSCQNGADCDSVT-----GKCTCAPGFKGIDCSTPCPLGTYGIN 451
TC G+ G+ C I C+ + C G+C C G+ G +C T CP +G +
Sbjct: 63 TCCAGWRQQGDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPD 121
Query: 452 CSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC----------------SIRCPSGTWGFGC 495
C C C C V G CTC A G C + RC G WG C
Sbjct: 122 CKELCSCHPHGQCEDVTGQCTCHARRWGARCEHACQCQHGTCHPRSGACRCEPGWWGAQC 181
Query: 496 NLTCQCLNGGACNTLDGTCTCAPGWRGEKCE----------------LPCQDGTYGLNCA 539
C C C+ G C C GW G C C++ T+G C
Sbjct: 182 ASACYCSATSRCDPQTGACLCHAGWWGRSCNNQCACNSSPCEQQSGRCQCRERTFGARCD 241
Query: 540 ERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC-YCKNGASCSPDDG 598
C C CHP G C C PG+ G +C C G +G C C CK C+ +G
Sbjct: 242 RYCQCFRGR-CHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEG 300
Query: 599 IC-ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD-CLPGFTGALC 656
C C PG+ GT C + C+ GFYG CS CP C C+H+TG C C G+ G C
Sbjct: 301 RCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPC-RDGHACNHVTGKCTRCNAGWIGDRC 359
Query: 657 NEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
C +G +G++CA +C +G C+ C C PG G C+ CPP G +C C
Sbjct: 360 ETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGADCAQAC 419
Query: 717 NCHNGAFCSAYDGEC 731
+CH C G C
Sbjct: 420 SCHEDT-CDPVTGAC 433
Score = 164 bits (416), Expect = 3e-40
Identities = 89/290 (30%), Positives = 117/290 (40%), Gaps = 55/290 (18%)
Query: 565 GVHCDSVCAEGRW-GPNCSLPCYCKNGASCSPDD-----GICECAPGFRGTTCQRICSPG 618
G + CA R G C + C+ ++CS ++ G C C G+ G C C
Sbjct: 58 GSQVPTCCAGWRQQGDECGI-AVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQ 116
Query: 619 FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNN 678
F+G C + C H G C +TG C C + R+G C C C +
Sbjct: 117 FWGPDCKELCS--CHPHGQCEDVTGQC-------------TCHARRWGARCEHACQC-QH 160
Query: 679 GTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
GTC+P +C+C PGW WG C C C + C G C C GW
Sbjct: 161 GTCHPRSGACRCEPGW-------------WGAQCASACYCSATSRCDPQTGACLCHAGWW 207
Query: 739 GLYCTQRCPLGF----------------YGKDCALICQCQNGADCDHISGQCTCRTGFMG 782
G C +C +G C CQC G C + G C C G+ G
Sbjct: 208 GRSCNNQCACNSSPCEQQSGRCQCRERTFGARCDRYCQCFRGR-CHPVDGTCACEPGYRG 266
Query: 783 RHCEQKCPSGTYGYGCRQIC-DCLNNSTCDHITGTCY-CSPGWKGARCDQ 830
++C + CP+G YG GCR+ C C C G C C PGW G +CDQ
Sbjct: 267 KYCREPCPAGFYGLGCRRRCGQCKGQQPCTVAEGRCLTCEPGWNGTKCDQ 316
Score = 158 bits (399), Expect = 3e-38
Identities = 80/201 (39%), Positives = 96/201 (47%), Gaps = 8/201 (3%)
Query: 102 GEMCVPHCADKCVHGRCI-APNTCQCEPGWGGTNCSSACDGDHWGPHCTSRC-QCKNGAL 159
G C +C +C GRC TC CEPG+ G C C +G C RC QCK
Sbjct: 237 GARCDRYC--QCFRGRCHPVDGTCACEPGYRGKYCREPCPAGFYGLGCRRRCGQCKGQQP 294
Query: 160 CNPITGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQRCQ-CQNGATCDHVTGEC-RCPPGY 216
C G C C G+ G +C+ C G YG C RC C++G C+HVTG+C RC G+
Sbjct: 295 CTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHVTGKCTRCNAGW 354
Query: 217 TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKN 276
G CE C G +G C C G C +G C C G G C CP G G +
Sbjct: 355 IGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
Query: 277 CSQECQCHNGGTCDAATGQCH 297
C+Q C CH TCD TG CH
Sbjct: 415 CAQACSCHED-TCDPVTGACH 434
Score = 139 bits (350), Expect = 2e-32
Identities = 77/211 (36%), Positives = 93/211 (44%), Gaps = 20/211 (9%)
Query: 53 DQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADK 112
++ + C F+ H V A G + Y R+ C GFY G C +
Sbjct: 233 ERTFGARCDRYCQCFRGRCHPVDGTCACEPGYRGKYCREP-CPAGFYGLG------CRRR 285
Query: 113 CVHGRCIAPNTCQ--------CEPGWGGTNCSSACDGDHWGPHCTSRCQ-CKNGALCNPI 163
C G+C C CEPGW GT C C +G C+ RC C++G CN +
Sbjct: 286 C--GQCKGQQPCTVAEGRCLTCEPGWNGTKCDQPCATGFYGEGCSHRCPPCRDGHACNHV 343
Query: 164 TGAC-HCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE 222
TG C C AG+ G RCE +C GTYG DC C CD +G C C PG G C
Sbjct: 344 TGKCTRCNAGWIGDRCETKCSNGTYGEDCAFVCADCGSGHCDFQSGRCLCSPGVHGPHCN 403
Query: 223 DLCPPGKHGPQCEQRCPCQNGGVCHHVTGEC 253
CPPG HG C Q C C C VTG C
Sbjct: 404 VTCPPGLHGADCAQACSCHE-DTCDPVTGAC 433
Score = 89.0 bits (219), Expect = 2e-17
Identities = 40/119 (33%), Positives = 53/119 (44%), Gaps = 19/119 (15%)
Query: 718 CHNGAFCSAYD-----GECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG 772
C + CS + GEC+C G+ G C +CP F+G DC +C C C+ ++G
Sbjct: 80 CEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHPHGQCEDVTG 139
Query: 773 QCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
QCTC G CE C + TC +G C C PGW GA+C A
Sbjct: 140 QCTCHARRWGARCEHACQC--------------QHGTCHPRSGACRCEPGWWGAQCASA 184
Score = 68.9 bits (167), Expect = 3e-11
Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 6/85 (7%)
Query: 752 GKDCALICQCQNGADCDHIS-----GQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLN 806
G +C I C+ + C G+C CR G+ G +C+ KCP +G C+++C C
Sbjct: 72 GDECG-IAVCEGNSTCSENEVCVRPGECRCRHGYFGANCDTKCPRQFWGPDCKELCSCHP 130
Query: 807 NSTCDHITGTCYCSPGWKGARCDQA 831
+ C+ +TG C C GARC+ A
Sbjct: 131 HGQCEDVTGQCTCHARRWGARCEHA 155
Score = 57.4 bits (137), Expect = 8e-08
Identities = 31/81 (38%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRC-IAPNTCQCEPGWGGTNCSSACDGDHWGPH 147
R +++C G Y GE C CAD C G C C C PG G +C+ C G
Sbjct: 358 RCETKCSNGTY--GEDCAFVCAD-CGSGHCDFQSGRCLCSPGVHGPHCNVTCPPGLHGAD 414
Query: 148 CTSRCQCKNGALCNPITGACH 168
C C C C+P+TGACH
Sbjct: 415 CAQACSCHEDT-CDPVTGACH 434
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 274 bits (700), Expect = 4e-73
Identities = 257/921 (27%), Positives = 316/921 (34%), Gaps = 265/921 (28%)
Query: 107 PHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDG-----DHWGPHCTSR-----CQC-- 154
PHC + C C GWGGT+C D G C R C C
Sbjct: 324 PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPP 383
Query: 155 -KNGALC-------------------NPITGA--CHCAAGFRGWRCE---DRCEQGTYGN 189
+ G LC NP+TG+ C C G+ G C D C G
Sbjct: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
Query: 190 DCHQRCQCQNGATCDHVTG--ECRCPPGYTGAFCED------------------------ 223
C++G +C + G C CPPGYTG+ CE
Sbjct: 444 S-----PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
Query: 224 -LCPPGKHGPQCE------QRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFG 274
LCPPG G CE PC N CH + +C C G+ GT C + E R
Sbjct: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR-- 556
Query: 275 KNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNG 329
C NGG C G C C PG+ G RCQ DEC + C G
Sbjct: 557 -----SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC----------LSDPCPVG 601
Query: 330 GKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECAC 387
C + GA CLC +GF G+ CE LC L C + C + C C
Sbjct: 602 ASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL----CQPKQICKDQKD------KANCLC 651
Query: 388 KPGWSGLYCNETCSPGFYGEACQQICSCQ---NGADCDSVTGKC---------TCAPGFK 435
G G E +G + C C G +C++ G C TC P
Sbjct: 652 PDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
Query: 436 GIDCSTPCPLGTYGINCSSRC------GCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCP 487
G +C+ CP G G CS C N C+P G CTC G C
Sbjct: 712 GYNCT--CPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ---- 765
Query: 488 SGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCE---------------LPCQ 530
T C ++ C NGG C GT C CA G++G +CE CQ
Sbjct: 766 --TSTDYC-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQ 822
Query: 531 DGTYGLNCAERCDCSHADGCHPT------------------TG---HCRCLPGWSGVHCD 569
D G C C + G T TG HC CL GW+G C+
Sbjct: 823 DSPQGPRCL--CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
Query: 570 ---SVCAEGRWGPNCSLPCYCKNGASC--SPDDGICECAPGFRGTTCQR----------- 613
S C + + C NG C S C C PGF+G+ CQ
Sbjct: 881 LPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQ 940
Query: 614 --------------ICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEV 659
C+PG+ G CS+ C S PCH+ G C PG G C
Sbjct: 941 NGATCMAQPSGYLCQCAPGYDGQNCSKELDAC--QSQPCHN-HGTCTPKPG--GFHC--A 993
Query: 660 CPSGRFGKNCAG--------ICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWG 709
CP G G C G C T C+ + + CQC PG G C P H
Sbjct: 994 CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQ 1053
Query: 710 PNCIHTCNCHNGAFCSAYDGE-----CKCTPGWTGLYCTQRCP-LGFYGKDCALICQCQN 763
P C +G C A G C C G+ G C+ R P GF+ C +
Sbjct: 1054 P-------CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH--------HCHH 1098
Query: 764 GADC-----DHISGQCTCRTGFMGRHC-EQKCPSGTYGYGCRQICDCLNNSTCDHITG-- 815
G C +C C +G+ G C P GC CL N +C TG
Sbjct: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK-----GCGPPSPCLYNGSCSETTGLG 1153
Query: 816 ----TCYCSPGWKGARCDQAG 832
C C G RC + G
Sbjct: 1154 GPGFRCSCPHSSPGPRCQKPG 1174
Score = 253 bits (647), Expect = 6e-67
Identities = 248/910 (27%), Positives = 318/910 (34%), Gaps = 274/910 (30%)
Query: 119 IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC--------------NPIT 164
+ TCQC PG+ G C + C + C+NG C +P+T
Sbjct: 46 LGQGTCQCAPGFLGETCQ-------FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLT 98
Query: 165 GA--CHCAAGFRGWRCEDR---------------------------CEQGTYGNDCHQR- 194
+ C C GF G RC+ + C G G C R
Sbjct: 99 PSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRD 158
Query: 195 -CQ---CQNGATC--DHVTGECRCPPGYTGAFCED------------------------- 223
C C NG C + +C CPPG+ G CE
Sbjct: 159 FCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSF 218
Query: 224 --LCPPGKHGPQCEQR---CP---CQNGGVCHHVTGE------CSCPSGWMGTVCGQPCP 269
LCP G+ GP+CE R CP C NGG C + + C CP G++G C + P
Sbjct: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC-EVNP 277
Query: 270 EGRFGKNCSQECQCHNGGTCDAA--TGQCHCSPGYTGERCQ---DECPVGTYGVLCAETC 324
+ NC QC NGGTC T C C +TG C DEC T G
Sbjct: 278 D-----NCVSH-QCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE--TQG-----PP 324
Query: 325 QCVNGGKCYHVSGA--CLCEAGFAGERCEAR------------------------LCPEG 358
C NGG C + +G+ C+C +G+ G CE LCP G
Sbjct: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
Query: 359 LYGIKC--DKRC---PCHLENTHSCHPMSGE--CACKPGWSGLYCNETCSPGFYGEACQQ 411
G+ C + C PCH + S +P++G C C+PG+SG C++ + Q
Sbjct: 385 RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQ--QG 442
Query: 412 ICSCQNGADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG 469
C++G C + G C C PG+ G C N+ + P
Sbjct: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEAD----------------HNECLSQPCHP 486
Query: 470 SCTCKAGWHGVDCSIRCPSGTWGFGCNL------TCQCLNGGACNTL--DGTCTCAPGWR 521
TC C CP G G C + + CLN C+ L C C PG+
Sbjct: 487 GSTCLDLLATFHC--LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS 544
Query: 522 GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNC 581
G +CE D CA C G HC+CLPG+ G C + E P
Sbjct: 545 GTRCEEDI-DECRSSPCANGGQCQDQPGAF----HCKCLPGFEGPRCQTEVDECLSDP-- 597
Query: 582 SLPCYCKNGASC--SPDDGICECAPGFRGTTCQ-RICSPGFYGHR-------------CS 625
C GASC P C C GF G C+ +C+P + C
Sbjct: 598 -----CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP 652
Query: 626 QTCPQCV--HSSGPCHH---ITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGT 680
P C + CHH C C G+TG C G C C + GT
Sbjct: 653 DGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC-----EAELG-GCIS-APCAHGGT 705
Query: 681 C--NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDG--ECKCTPG 736
C P +C C G+ G CS+ H GP C NG C+ G C C P
Sbjct: 706 CYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPS 758
Query: 737 WTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCEQK------ 788
TG C D + C NG C + G C C GF G CE K
Sbjct: 759 HTGPQCQT-------STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
Query: 789 --------------------CPSGTYGYGCRQICD------CLNNSTCDHITGT---CYC 819
CP+G G C+ + D C NS C TG C C
Sbjct: 812 DSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ-TGPSFHCLC 870
Query: 820 SPGWKGARCD 829
GW G C+
Sbjct: 871 LQGWTGPLCN 880
Score = 229 bits (583), Expect = 1e-59
Identities = 240/849 (28%), Positives = 307/849 (36%), Gaps = 203/849 (23%)
Query: 57 YTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHG 116
+ C D+LN F+C C PGF SG C D+C
Sbjct: 525 HADCHDLLNGFQCI-----------------------CLPGF--SGTRC-EEDIDECRSS 558
Query: 117 RCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQ------CKNGALCNPITGA--CH 168
C CQ +PG C + GP C + C GA C + GA C
Sbjct: 559 PCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
Query: 169 CAAGFRGWRCE------DRCEQGTYGNDCHQR--CQCQNGAT-CDHVTGECRCPPGYTGA 219
C +GF G CE + C+ D + C C +G+ C C C G+
Sbjct: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR 674
Query: 220 FCEDLCPPGKHGPQCEQR------CPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEG 271
+C G GP+CE PC +GG C+ C+CP+G+ G C +
Sbjct: 675 -SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC 733
Query: 272 RFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG 329
G C NGG+C+ + G C C P +TG +CQ T C + C NG
Sbjct: 734 HSG-------PCLNGGSCNPSPGGYYCTCPPSHTGPQCQ------TSTDYCV-SAPCFNG 779
Query: 330 GKCYHVSG--ACLCEAGFAGERCEAR-------------------------LCPEGLYGI 362
G C + G +CLC GF G RCE + LCP G G
Sbjct: 780 GTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
Query: 363 KC--------DKRCPCHLENTHSCHP-MSGECACKPGWSGLYCN---ETCSPGFYGEACQ 410
C K CP N+H S C C GW+G CN +C +
Sbjct: 840 SCQTLMDLCAQKPCP---RNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
Query: 411 QICSCQNGADC--DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC--SP 466
C NG C + C C PGF+G C + C SR C+N A C P
Sbjct: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ------DHVNPCESR-PCQNGATCMAQP 949
Query: 467 VDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ---CLNGGACNTLDG--TCTCAPGWR 521
C C G+ G +CS + CQ C N G C G C C PG+
Sbjct: 950 SGYLCQCAPGYDGQNCSKELDA----------CQSQPCHNHGTCTPKPGGFHCACPPGFV 999
Query: 522 GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGP 579
G +CE G + C + CH +C+CLPG +G C E P
Sbjct: 1000 GLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWC-----EVEIDP 1049
Query: 580 NCSLPCYCKNGASC-----SPDDGICECAPGFRGTTC-QRICSPGFYGHRCSQTCPQCVH 633
S PC+ +G +C SP IC C GF G TC R S GF H C C+
Sbjct: 1050 CHSQPCF--HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF--HHCHHG-GLCLP 1104
Query: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPG 693
S P C CL G+ G C + P K C C NG+C+ G
Sbjct: 1105 SPKP--GFPPRCACLSGYGGPDC--LTPPA--PKGCGPPSPCLYNGSCSETTGL-----G 1153
Query: 694 WIGSDCSQPCPPAHWGPNC----IHTCNCHNG-----AFCSAYDGEC---KCTPG----W 737
G CS CP + GP C C +G A CS G C+ G W
Sbjct: 1154 GPGFRCS--CPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPW 1211
Query: 738 TGLYCTQRCPLGFYGKDCALICQCQ----NGADCDHISGQCT------CRTGFMGRHCEQ 787
G RC L F C C + +G DC+ CT C F HCE+
Sbjct: 1212 KGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCE-TPPACTPAYDQYCHDHFHNGHCEK 1270
Query: 788 KCPSGTYGY 796
C + G+
Sbjct: 1271 GCNTAECGW 1279
Score = 205 bits (522), Expect = 2e-52
Identities = 227/841 (26%), Positives = 280/841 (33%), Gaps = 268/841 (31%)
Query: 94 CCPGFYESGEMCVPHCADKCVHGRCIAPNTCQ---------CEPGWGGTNCSSACDGDHW 144
C PG G++C ++C C+ C C PG+ GT C D
Sbjct: 501 CPPGL--EGQLCEVE-TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557
Query: 145 GPHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGAT 202
P C NG C GA C C GF G RC+ T ++C C GA+
Sbjct: 558 SP-------CANGGQCQDQPGAFHCKCLPGFEGPRCQ------TEVDECLSD-PCPVGAS 603
Query: 203 CDHVTGE--CRCPPGYTGAFCE-DLCPPGKHGPQ--CEQR-----CPCQNGG-------- 244
C + G C CP G+TG CE LC P P+ C+ + C C +G
Sbjct: 604 CLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPED 663
Query: 245 --VCHH---VTGECSCPSGWMGTVCG-------------------QP------CPEGRFG 274
CHH C C GW G C QP CP G G
Sbjct: 664 NCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTG 723
Query: 275 KNCSQECQ------CHNGGTCDAATG--QCHCSPGYTGERCQDECPVGTYGVLCAETCQC 326
CS+E C NGG+C+ + G C C P +TG +CQ T C + C
Sbjct: 724 PTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ------TSTDYCV-SAPC 776
Query: 327 VNGGKCYHVSG--ACLCEAGFAGERCEARL-------------------------CPEGL 359
NGG C + G +CLC GF G RCE +L CP G
Sbjct: 777 FNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGY 836
Query: 360 YGIKCD--------KRCPCHLENTHSCHP-MSGECACKPGWSGLYCNET----------- 399
G C K CP N+H S C C GW+G CN
Sbjct: 837 TGGSCQTLMDLCAQKPCP---RNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQ 893
Query: 400 ------------------------CSPGFYGEACQQICS------CQNGADCDSVTGK-- 427
C PGF G CQ + CQNGA C +
Sbjct: 894 GIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
Query: 428 CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCS-- 483
C CAPG+ G +CS C S+ C N C+P G C C G+ G+ C
Sbjct: 954 CQCAPGYDGQNCSKELDA------CQSQ-PCHNHGTCTPKPGGFHCACPPGFVGLRCEGD 1006
Query: 484 -IRC------PSGTWGFGCN-----LTCQCLNGGA---CNTLDGTCTCAPGWRGEKCELP 528
C P+GT C+ CQCL G C C P + G CE
Sbjct: 1007 VDECLDQPCHPTGT--AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
Query: 529 ----------CQDGTYGLNCAERCD------CSHADGCHPTTG-----HCRCLPGWSGVH 567
C G G C+ R C H C P+ C CL G+ G
Sbjct: 1065 AGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPD 1124
Query: 568 CDSVCAEGRWGPNCSLPCYCKNGASCSPDDGI------CECAPGFRGTTCQRICSPGFYG 621
C + A GP P C SCS G+ C C G CQ+ + G G
Sbjct: 1125 CLTPPAPKGCGP----PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEG 1180
Query: 622 HRCSQTCPQCVHSSGPCHHITGLCDCLPG-----------------FTGALCNEVCPSGR 664
C SGP + G DC G F C+ C S
Sbjct: 1181 RSGDGACD--AGCSGPGGNWDG-GDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEE 1237
Query: 665 F---GKNCAGICTCT-----------NNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGP 710
G +C CT +NG C + +C GW G DC WGP
Sbjct: 1238 CLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAEC--GWDGGDCRPEDGDPEWGP 1295
Query: 711 N 711
+
Sbjct: 1296 S 1296
Score = 186 bits (471), Expect = 1e-46
Identities = 169/612 (27%), Positives = 218/612 (35%), Gaps = 152/612 (24%)
Query: 95 CPGFYESGEMCVPHCADK---CVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHC--- 148
CP Y P C+++ C G C+ N C P GG C+ C H GP C
Sbjct: 717 CPTGYTG-----PTCSEEMTACHSGPCL--NGGSCNPSPGGYYCT--CPPSHTGPQCQTS 767
Query: 149 TSRC---QCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC 203
T C C NG C P T +C CA GF+G RCE + + C R CQ+
Sbjct: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQG 827
Query: 204 DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTV 263
C CP GYTG C+ L P C + C G H C C GW G +
Sbjct: 828 PR----CLCPTGYTGGSCQTLMDLCAQKP-CPRNSHCLQTGPSFH----CLCLQGWTGPL 878
Query: 264 CGQP---CPEGRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQDECPVGTYGV 318
C P C + + CHNGG C + CHC PG+ G CQD V
Sbjct: 879 CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-------V 931
Query: 319 LCAETCQCVNGGKCY-HVSG-ACLCEAGFAGERCEARL---------------------- 354
E+ C NG C SG C C G+ G+ C L
Sbjct: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991
Query: 355 --CPEGLYGIKCD---KRC---PCHLENTHSCHPMSGE--CACKPGWSGLYCN---ETC- 400
CP G G++C+ C PCH T +CH ++ C C PG +G +C + C
Sbjct: 992 CACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCH 1051
Query: 401 -SPGFYGEACQQ--------ICSCQNGADCDSVTGK------------------------ 427
P F+G C+ IC C G + + + +
Sbjct: 1052 SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFP 1111
Query: 428 --CTCAPGFKGIDCSTP-CPLGT-------YGINCSS---------RCGCKNDAV---CS 465
C C G+ G DC TP P G Y +CS RC C + + C
Sbjct: 1112 PRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ 1171
Query: 466 -PVDGSCTCKAGWHGVDCSIRCPSGTW-GFGCNLTCQ-----CLNGGACNTLDGTCTCAP 518
P C ++G D P G W G C+L C + C L C P
Sbjct: 1172 KPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHP 1231
Query: 519 GWRGEKCELPCQDGTYGLNCAERCDCSHADGCHP--TTGHCR-----CLPGWSGVHCDSV 571
E+C DG Y C ++ CH GHC GW G C
Sbjct: 1232 QCDSEECLF---DG-YDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPE 1287
Query: 572 CAEGRWGPNCSL 583
+ WGP+ +L
Sbjct: 1288 DGDPEWGPSLAL 1299
Score = 141 bits (355), Expect = 4e-33
Identities = 122/448 (27%), Positives = 162/448 (36%), Gaps = 126/448 (28%)
Query: 458 CKNDAVCSPVD---GSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTL---- 510
C N C + G+C C G+ G C P C C NGG+C L
Sbjct: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-------CQNAQLCQNGGSCQALLPAP 87
Query: 511 ------------DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCR 558
CTC PG+ GE+C+ +D C++R C P C
Sbjct: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRP---QCS 144
Query: 559 CLPGWSGVHCD--SVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICS 616
C+PGW+G C C+ C NG C +C C
Sbjct: 145 CMPGWTGEQCQLRDFCSANP----------CVNGGVCLATYPQIQCH-----------CP 183
Query: 617 PGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC---AGIC 673
PGF GH C + +C GPC T + L F C +CP G+ G C AG C
Sbjct: 184 PGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ---C--LCPVGQEGPRCELRAGPC 238
Query: 674 T---CTNNGTCNPIDRS------CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC 724
C+N GTC + C C PG+IG DC NC+ + C NG C
Sbjct: 239 PPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN------PDNCV-SHQCQNGGTC 291
Query: 725 SAYDG----ECKCTPGWTGLYCTQRCPLGFYGKDCAL--ICQCQNGADCDHISG--QCTC 776
DG C C WTG C++ +C C+NG C + +G C C
Sbjct: 292 Q--DGLDTYTCLCPETWTGWDCSEDV------DECETQGPPHCRNGGTCQNSAGSFHCVC 343
Query: 777 RTGFMGRHCEQK-------------------------CPSGTYGYGC--RQIC---DCLN 806
+G+ G CE+ CP G G C +C C
Sbjct: 344 VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHG 403
Query: 807 NSTC--DHITGT--CYCSPGWKGARCDQ 830
++ C + +TG+ C C PG+ G C Q
Sbjct: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQ 431
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 270 bits (689), Expect = 8e-72
Identities = 255/882 (28%), Positives = 339/882 (38%), Gaps = 249/882 (28%)
Query: 93 QCCPGFYESGEMCVPHCADKCVHGRC-----------IAPNTCQCEPGWGGTNC------ 135
+C GF GE C D C RC + TC+C G+ G +C
Sbjct: 52 KCPEGFL--GEYCQHR--DPCEKNRCQNGGTCVAQAMLGKATCRCASGFTGEDCQYSTSH 107
Query: 136 ----------------------SSACDGDHWGPHC--TSRC---QCKNGALCNPITG--A 166
C G C T C C NG+ C + +
Sbjct: 108 PCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFS 167
Query: 167 CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTG--ECRCPPGYTGAFCEDL 224
C C GF G +CE T N+C CQ+G TC ++ G +C+CP G+TG +C+ L
Sbjct: 168 CKCLTGFTGQKCE------TDVNECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL 221
Query: 225 CPPGKHGPQCEQRCPCQNGGVCHHV---TGECSCPSGWMGTVCGQ---PCPEGRFGKNCS 278
P C PC NGG C T EC+C G+ G+ C + CP R
Sbjct: 222 YVP------CAP-SPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR------ 268
Query: 279 QECQCHNGGTC--DAATGQCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCY 333
C NGG C T C C P +TG+ C DEC +L CQ NGG C
Sbjct: 269 ----CQNGGVCVDGVNTYNCRCPPQWTGQFCTEDVDEC------LLQPNACQ--NGGTCA 316
Query: 334 HVSG--ACLCEAGFAGERCEAR------------------------LCPEGLYGIKC--D 365
+ +G C+C G++G+ C +CPEG G+ C D
Sbjct: 317 NRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLD 376
Query: 366 KRC---PCHLENTHSCHPMSGE--CACKPGWSGLYCNETCSPGFYGEACQQICS--CQNG 418
C PCH +P++G+ C C G+ G C E + C S C++
Sbjct: 377 DACISNPCHKGALCDTNPLNGQYICTCPQGYKGADCTEDV------DECAMANSNPCEHA 430
Query: 419 ADCDSVTG--KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCK 474
C + G C C G+ G C IN C+NDA C G +C C
Sbjct: 431 GKCVNTDGAFHCECLKGYAGPRCE-------MDINECHSDPCQNDATCLDKIGGFTCLCM 483
Query: 475 AGWHGVDCSI---RCPSGTWGFGCNLTCQCLNGGAC--NTLDGTCTCAPGWRGEKCELPC 529
G+ GV C + C S C+N G C C C PG+ G C++
Sbjct: 484 PGFKGVHCELEINECQSN----------PCVNNGQCVDKVNRFQCLCPPGFTGPVCQIDI 533
Query: 530 QD--GTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYC 587
D T LN A+ D HP C+C G++GV C+ NC P C
Sbjct: 534 DDCSSTPCLNGAKCID-------HPNGYECQCATGFTGVLCEENI------DNCD-PDPC 579
Query: 588 KNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDC 647
+G +C G TC IC+PG+ G CS +C S PC + D
Sbjct: 580 HHG----------QCQDGIDSYTC--ICNPGYMGAICSDQIDECY--SSPCLNDGRCIDL 625
Query: 648 LPGFTGALCNEVCPSGRFGKNC-AGICTCTNN----GTC-NPIDR-SCQCYPGWIGSDCS 700
+ G+ CN C G G NC C +N G C + I+R SC C PG+ G C+
Sbjct: 626 VNGYQ---CN--CQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCN 680
Query: 701 ---QPCP--PAHWGPNCIH-----TCNCHNGAF---CSAYDGEC--------KCTPGWTG 739
C P G CI+ C C G C + EC CT G +G
Sbjct: 681 IDIDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSG 740
Query: 740 LYCTQRCPLGFYGKDC------ALICQCQNGADCDHISG--QCTCRTGFMGRHCE---QK 788
C C G+ G +C L CQNG CD++ +CTC+ GF G +C+ +
Sbjct: 741 YKCL--CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDE 798
Query: 789 CPSGTYGYGCRQICDCLNNSTC-DHITG-TCYCSPGWKGARC 828
C S CLN TC D I+G TC+C + G C
Sbjct: 799 CASN----------PCLNQGTCFDDISGYTCHCVLPYTGKNC 830
Score = 265 bits (678), Expect = 1e-70
Identities = 262/919 (28%), Positives = 334/919 (36%), Gaps = 256/919 (27%)
Query: 59 SCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMC---VPHC-ADKCV 114
S T LN KC H Y + QC GF +G +C + +C D C
Sbjct: 537 SSTPCLNGAKCIDHPNGY--------------ECQCATGF--TGVLCEENIDNCDPDPCH 580
Query: 115 HGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA--CHC 169
HG+C I TC C PG+ G CS D + P C N C + C+C
Sbjct: 581 HGQCQDGIDSYTCICNPGYMGAICSDQIDECYSSP-------CLNDGRCIDLVNGYQCNC 633
Query: 170 AAGFRGWRCE--------DRCEQGTYGNDCHQ-RCQCQNGAT---CDHVTGECRCPPGYT 217
G G CE + C G + ++ C C G T C+ EC P
Sbjct: 634 QPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRK 693
Query: 218 GAFCED-------LCPPGKHGPQCEQRC------PCQNGGVCHHVTG-ECSCPSGWMGTV 263
GA C + +CP G H P C + PC +G ++G +C C +GW+G
Sbjct: 694 GATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGIN 753
Query: 264 CGQPCPEGRFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQ---DECPVGTYGV 318
C KN C NGGTCD +C C G+ G CQ DEC
Sbjct: 754 C-------EVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNP--- 803
Query: 319 LCAETCQCVNGGKCYH-VSG-ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH 376
C+N G C+ +SG C C + G+ C+ L P C PC EN
Sbjct: 804 -------CLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAP-------CSPN-PC--ENAA 846
Query: 377 SCHPM----SGECACKPGWSGLYCNET-------------------------CSPGFYGE 407
C S C C PGW G C C PGF G
Sbjct: 847 VCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGM 906
Query: 408 ACQQICS------CQNGADC-DSV-TGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCK 459
C++ CQNG C D V T C C PGF G C T C S CK
Sbjct: 907 DCEEDIDDCLANPCQNGGSCMDGVNTFSCLCLPGFTGDKCQTDMN------ECLSE-PCK 959
Query: 460 NDAVCSPVDGS--CTCKAGWHGVDC-------------------------SIRCPSGTWG 492
N CS S C C+AG+ GV C S CP G G
Sbjct: 960 NGGTCSDYVNSYTCKCQAGFDGVHCENNINECTESSCFNGGTCVDGINSFSCLCPVGFTG 1019
Query: 493 FGCNLTCQ------CLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDC 544
C CLN G C GT C+C G+ G+ C+ +N R C
Sbjct: 1020 SFCLHEINECSSHPCLNEGTCVDGLGTYRCSCPLGYTGKNCQTL-------VNLCSRSPC 1072
Query: 545 SHADGC--HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGAS--------CS 594
+ C C C GW+G +CD PN S C AS
Sbjct: 1073 KNKGTCVQKKAESQCLCPSGWAGAYCDV--------PNVS----CDIAASRRGVLVEHLC 1120
Query: 595 PDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH-------ITGL-CD 646
G+C A G T C G+ G C + +C +S PC H I G C+
Sbjct: 1121 QHSGVCINA----GNTHYCQCPLGYTGSYCEEQLDEC--ASNPCQHGATCSDFIGGYRCE 1174
Query: 647 CLPGFTGALCN---EVCPSGRFGKNCAGICTCTNNGTCNPIDR--SCQCYPGWIGSDCSQ 701
C+PG+ G C + C + C N GTC + C C PG G C +
Sbjct: 1175 CVPGYQGVNCEYEVDECQNQ----------PCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 702 PCPPAHWGPNCIHTCNCHNGAFCSAYDG--ECKCTPGWTGLYCTQRCPLGFYGKDCALIC 759
GP+C+ NG C G C+C PG+ G +RC G + + C
Sbjct: 1225 NIDDCARGPHCL------NGGQCMDRIGGYSCRCLPGFAG----ERCE-GDINECLSNPC 1273
Query: 760 QCQNGADCDHISGQ--CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGT- 816
+ DC ++ C CR+ F GRHCE T+ C Q+ CLN TC +
Sbjct: 1274 SSEGSLDCIQLTNDYLCVCRSAFTGRHCE------TFVDVCPQM-PCLNGGTCAVASNMP 1326
Query: 817 ----CYCSPGWKGARCDQA 831
C C PG+ GARC +
Sbjct: 1327 DGFICRCPPGFSGARCQSS 1345
Score = 262 bits (669), Expect = 2e-69
Identities = 257/910 (28%), Positives = 338/910 (37%), Gaps = 264/910 (29%)
Query: 111 DKCVH-GRCIAPNT----CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITG 165
+ CV+ G C+ + C+C G+ G C H P +RCQ + + G
Sbjct: 33 EPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ------HRDPCEKNRCQNGGTCVAQAMLG 86
Query: 166 --ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHV---TGECRCPPGYTGAF 220
C CA+GF G C Q + + C C NG TC + T EC C G+TG
Sbjct: 87 KATCRCASGFTGEDC-----QYSTSHPCFVSRPCLNGGTCHMLSRDTYECTCQVGFTGKE 141
Query: 221 CE--DLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKN 276
C+ D C PC NG C V + C C +G+ G C E
Sbjct: 142 CQWTDACLSH----------PCANGSTCTTVANQFSCKCLTGFTGQKCETDVNE------ 185
Query: 277 CSQECQCHNGGTCDAATG--QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH 334
C C +GGTC G QC C G+TG+ C + V CA + CVNGG C
Sbjct: 186 CDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCD------SLYVPCAPS-PCVNGGTCRQ 238
Query: 335 VSG---ACLCEAGFAGERCEARL--CPEGLYGIKCDKRCPC-HLENTHSCHPMSGECACK 388
C C GF G CE + CP +C C NT++C C
Sbjct: 239 TGDFTFECNCLPGFEGSTCERNIDDCPNH----RCQNGGVCVDGVNTYNCR-------CP 287
Query: 389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKGIDCS------ 440
P W+G +C E E Q +CQNG C + G C C G+ G DCS
Sbjct: 288 PQWTGQFCTEDVD-----ECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDC 342
Query: 441 -----TP--------------CPLGTYGINC--SSRC---GCKNDAVC--SPVDGS--CT 472
TP CP G G+ C C C A+C +P++G CT
Sbjct: 343 AFASCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICT 402
Query: 473 CKAGWHGVDCSIRCPSGTWGFGCNLTCQ--CLNGGACNTLDGT--CTCAPGWRGEKCELP 528
C G+ G DC+ C + C + G C DG C C G+ G +CE+
Sbjct: 403 CPQGYKGADCTEDVDE------CAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMD 456
Query: 529 CQDGTYGLNCAERCDCSHADGCHPTTGH--CRCLPGWSGVHCD----------------- 569
+N C + C G C C+PG+ GVHC+
Sbjct: 457 -------INECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQC 509
Query: 570 --------SVCAEGRWGPNCSLPCY------CKNGASC--SPDDGICECAPGFRGTTCQR 613
+C G GP C + C NGA C P+ C+CA GF G C+
Sbjct: 510 VDKVNRFQCLCPPGFTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEE 569
Query: 614 ------------------------ICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLP 649
IC+PG+ G CS +C S PC + D +
Sbjct: 570 NIDNCDPDPCHHGQCQDGIDSYTCICNPGYMGAICSDQIDECY--SSPCLNDGRCIDLVN 627
Query: 650 GFTGALCNEVCPSGRFGKNCA-GICTCTNN----GTC-NPIDR-SCQCYPGWIGSDCS-- 700
G+ CN C G G NC C +N G C + I+R SC C PG+ G C+
Sbjct: 628 GYQ---CN--CQPGTSGVNCEINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNID 682
Query: 701 -QPCP--PAHWGPNCIH-----TCNCHNGAF---CSAYDGEC--------KCTPGWTGLY 741
C P G CI+ C C G C + EC CT G +G
Sbjct: 683 IDECASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYK 742
Query: 742 CTQRCPLGFYGKDC------ALICQCQNGADCDHISG--QCTCRTGFMGRHCE---QKCP 790
C C G+ G +C L CQNG CD++ +CTC+ GF G +C+ +C
Sbjct: 743 CL--CDAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECA 800
Query: 791 S------GTY-----GYGCRQICD-----------------CLNNSTCDHITG----TCY 818
S GT GY C + C N + C TC
Sbjct: 801 SNPCLNQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCL 860
Query: 819 CSPGWKGARC 828
C+PGW+G RC
Sbjct: 861 CAPGWQGQRC 870
Score = 258 bits (660), Expect = 2e-68
Identities = 283/1027 (27%), Positives = 355/1027 (34%), Gaps = 331/1027 (32%)
Query: 58 TSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGR 117
++CT + N F C +C GF +G+ C + + G
Sbjct: 157 STCTTVANQFSC-----------------------KCLTGF--TGQKCETDVNECDIPGH 191
Query: 118 CIAPNTC---------QCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNP---ITG 165
C TC QC G+ G C S + P S C NG C T
Sbjct: 192 CQHGGTCLNLPGSYQCQCPQGFTGQYCDSL-----YVPCAPS--PCVNGGTCRQTGDFTF 244
Query: 166 ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC-DHV-TGECRCPPGYTGAFC-E 222
C+C GF G CE + DC +CQNG C D V T CRCPP +TG FC E
Sbjct: 245 ECNCLPGFEGSTCERNID------DCPNH-RCQNGGVCVDGVNTYNCRCPPQWTGQFCTE 297
Query: 223 DLCPPGKHGPQCE-QRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQP------------ 267
D+ +C Q CQNGG C + G C C +GW G C +
Sbjct: 298 DV-------DECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFASCTPG 350
Query: 268 -------------CPEGRFGKNCSQE--C---QCHNGGTCDA--ATGQ--CHCSPGYTGE 305
CPEG+ G C + C CH G CD GQ C C GY G
Sbjct: 351 STCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQGYKGA 410
Query: 306 RCQ---DECPVGT-----YGVLCAET-----CQCVNG----------GKCYH-------- 334
C DEC + + C T C+C+ G +C+
Sbjct: 411 DCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSDPCQNDAT 470
Query: 335 ----VSG-ACLCEAGFAGERCEAR------------------------LCPEGLYGIKCD 365
+ G CLC GF G CE LCP G G C
Sbjct: 471 CLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPGFTGPVCQ 530
Query: 366 ------KRCPCHLENTHSC--HPMSGECACKPGWSGLYCNET------------------ 399
PC N C HP EC C G++G+ C E
Sbjct: 531 IDIDDCSSTPCL--NGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHGQCQDGI 588
Query: 400 ------CSPGFYGEACQ-QICSC------QNGADCDSVTG-KCTCAPGFKGIDC------ 439
C+PG+ G C QI C +G D V G +C C PG G++C
Sbjct: 589 DSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNCEINFDD 648
Query: 440 --STPCPLGTY--GIN-----CS-----SRCGCKNDAVCS-PVDGSCTCKAGWHGVDCSI 484
S PC G GIN CS RC D S P TC G +G C
Sbjct: 649 CASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVNGFRCI- 707
Query: 485 RCPSGTWGFGCN------LTCQCLNGGACNTLDG-TCTCAPGWRGEKCEL--------PC 529
CP G C L+ C++G L G C C GW G CE+ PC
Sbjct: 708 -CPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSNPC 766
Query: 530 QDGTYGLNCAE--RCDCS----------HADGC--HPTTGHCRCLPGWSGVHCDSVCAEG 575
Q+G N RC C + D C +P C SG C C
Sbjct: 767 QNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCH--CVLP 824
Query: 576 RWGPNCSLPCYCKNGASCSPDD----GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC 631
G NC A CSP+ +C+ +P F TC +C+PG+ G RC+ +C
Sbjct: 825 YTGKNCQTVL-----APCSPNPCENAAVCKESPNFESYTC--LCAPGWQGQRCTIDIDEC 877
Query: 632 VH----SSGPCHHITG--LCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTC--NP 683
+ + G CH+ G +C+C PGF+G C E +C C N G+C
Sbjct: 878 ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDID------DCLAN-PCQNGGSCMDGV 930
Query: 684 IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLY 741
SC C PG+ G C P C NG CS Y CKC G+ G++
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEP-------CKNGGTCSDYVNSYTCKCQAGFDGVH 983
Query: 742 CTQRCPLGFYGKDCALICQCQNGADC-DHISG-QCTCRTGFMGRHCEQK----------- 788
C +C C NG C D I+ C C GF G C +
Sbjct: 984 CENNI------NECTE-SSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLN 1036
Query: 789 --------------CPSGTYGYGCRQICD------CLNNSTC--DHITGTCYCSPGWKGA 826
CP G G C+ + + C N TC C C GW GA
Sbjct: 1037 EGTCVDGLGTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGA 1096
Query: 827 RCDQAGV 833
CD V
Sbjct: 1097 YCDVPNV 1103
Score = 253 bits (645), Expect = 9e-67
Identities = 242/888 (27%), Positives = 317/888 (35%), Gaps = 260/888 (29%)
Query: 96 PGFYESGEMCVPHCADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRC 152
P Y C+ ++ C+HG C ++ C C+ GW G NC + C S
Sbjct: 715 PSCYSQVNECL---SNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKN------ECLSN- 764
Query: 153 QCKNGALCNPITGA--CHCAAGFRGWRCE---DRC------EQGTYGNDCH-QRCQC--- 197
C+NG C+ + C C GF+G+ C+ D C QGT +D C C
Sbjct: 765 PCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCLNQGTCFDDISGYTCHCVLP 824
Query: 198 QNGATCDHVTGECRCPPGYTGAFCED---------LCPPGKHGPQCE---QRC---PCQN 242
G C V C P A C++ LC PG G +C C PC N
Sbjct: 825 YTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDECISKPCMN 884
Query: 243 GGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC--DAATGQCHC 298
G+CH+ G C CP G+ G C + + C C NGG+C T C C
Sbjct: 885 HGLCHNTQGSYMCECPPGFSGMDCEEDIDD------CLAN-PCQNGGSCMDGVNTFSCLC 937
Query: 299 SPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKC--YHVSGACLCEAGFAGERCEAR 353
PG+TG++CQ +EC +E C+ NGG C Y S C C+AGF G CE
Sbjct: 938 LPGFTGDKCQTDMNEC--------LSEPCK--NGGTCSDYVNSYTCKCQAGFDGVHCENN 987
Query: 354 L-------------CPEGLYGIKCDKRCPC--------HLENTHSCHPMSGECACKPGWS 392
+ C +G+ C CP H N S HP E C G
Sbjct: 988 INECTESSCFNGGTCVDGINSFSC--LCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLG 1045
Query: 393 GLYCNETCSPGFYGEACQ---QICS---CQNGADC--DSVTGKCTCAPGFKGIDCSTP-- 442
C+ C G+ G+ CQ +CS C+N C +C C G+ G C P
Sbjct: 1046 TYRCS--CPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNV 1103
Query: 443 ---------------------------------CPLGTYGINCSSRCG------CKNDAV 463
CPLG G C + C++ A
Sbjct: 1104 SCDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGAT 1163
Query: 464 CSPVDGS--CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ---CLNGGACNTLDG--TCTC 516
CS G C C G+ GV+C CQ C NGG C L C+C
Sbjct: 1164 CSDFIGGYRCECVPGYQGVNCEYEVDE----------CQNQPCQNGGTCIDLVNHFKCSC 1213
Query: 517 APGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDS------ 570
PG RG CE D G +C C G + CRCLPG++G C+
Sbjct: 1214 PPGTRGLLCEENIDDCARGPHCLNGGQCMDRIGGYS----CRCLPGFAGERCEGDINECL 1269
Query: 571 ---------------------VCAEGRWGPNCS--------LPCYCKNGASCS-----PD 596
VC G +C +PC NG +C+ PD
Sbjct: 1270 SNPCSSEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPCL--NGGTCAVASNMPD 1327
Query: 597 DGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALC 656
IC C PGF G CQ C G + QCVH++ +G C
Sbjct: 1328 GFICRCPPGFSGARCQSSC-----GQVKCRKGEQCVHTA----------------SGPRC 1366
Query: 657 NEVCPSGRFGKNCAGICTCTNNGTCNPIDR----SCQCYPGWIGSDC------------- 699
CPS R ++ C + G+C+P + SCQC P + GS C
Sbjct: 1367 --FCPSPRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPAT 1424
Query: 700 --SQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFY-GKDCA 756
SQ C C CN H C G+C T C+ P Y C
Sbjct: 1425 CLSQYCADKARDGVCDEACNSH---ACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCD 1481
Query: 757 LIC---QCQ-NGADCDHISGQCT----CRTGFMGRHCEQKCPSGTYGY 796
+C +C + +C S C C F HC+Q C S G+
Sbjct: 1482 ELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGW 1529
Score = 137 bits (344), Expect = 8e-32
Identities = 130/489 (26%), Positives = 178/489 (36%), Gaps = 142/489 (29%)
Query: 116 GRCI---APNTCQCEPGWGGTNC---SSACD--GDHWGPHCTSRCQCKNGALCNPITGAC 167
G C+ A + C C GW G C + +CD G CQ + T C
Sbjct: 1076 GTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIAASRRGVLVEHLCQHSGVCINAGNTHYC 1135
Query: 168 HCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTG--ECRCPPGYTGAFCEDLC 225
C G+ G CE++ ++ C CQ+GATC G C C PGY G CE
Sbjct: 1136 QCPLGYTGSYCEEQLDE------CASN-PCQHGATCSDFIGGYRCECVPGYQGVNCE--- 1185
Query: 226 PPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQC 283
+C+ + PCQNGG C + +CSCP G G +C + + C++ C
Sbjct: 1186 ---YEVDECQNQ-PCQNGGTCIDLVNHFKCSCPPGTRGLLCEENIDD------CARGPHC 1235
Query: 284 HNGGTCDAATG--QCHCSPGYTGERCQ---DEC---PVGTYGVL-CAET----------- 323
NGG C G C C PG+ GERC+ +EC P + G L C +
Sbjct: 1236 LNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQLTNDYLCVCRSA 1295
Query: 324 -----CQ----------CVNGGKCYHVSGA-----CLCEAGFAGERCEARL----CPEGL 359
C+ C+NGG C S C C GF+G RC++ C +G
Sbjct: 1296 FTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQSSCGQVKCRKGE 1355
Query: 360 YGIK--------------CDKRC---PCHLENTHSCHPMSG----ECACKPGWSGLYC-- 396
+ C+ C PC ++ SCHP C C P +SG C
Sbjct: 1356 QCVHTASGPRCFCPSPRDCESGCASSPC--QHGGSCHPQRQPPYYSCQCAPPFSGSRCEL 1413
Query: 397 -------------NETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPC 443
++ C+ C + C N C G C+ +CS+P
Sbjct: 1414 YTAPPSTPPATCLSQYCADKARDGVCDEAC---NSHACQWDGGDCSLTMENPWANCSSPL 1470
Query: 444 PLGTYGIN-CSSRCG-----------------CKNDAVCSP------VDGSCTCK-AGWH 478
P Y N C C CK D C+ D C + GW
Sbjct: 1471 PCWDYINNQCDELCNTVECLFDNFECQGNSKTCKYDKYCADHFKDNHCDQGCNSEECGWD 1530
Query: 479 GVDCSIRCP 487
G+DC+ P
Sbjct: 1531 GLDCAADQP 1539
Score = 92.8 bits (229), Expect = 2e-18
Identities = 75/271 (27%), Positives = 110/271 (40%), Gaps = 51/271 (18%)
Query: 581 CSLPCY---CKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCP----QCVH 633
C+ P + C++G ++G+C + T C GF G C P +C
Sbjct: 19 CAAPAHALQCRDGYEPCVNEGMCVT---YHNGTGYCKCPEGFLGEYCQHRDPCEKNRC-Q 74
Query: 634 SSGPCHHITGL----CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS-- 687
+ G C L C C GFTG C F C N GTC+ + R
Sbjct: 75 NGGTCVAQAMLGKATCRCASGFTGEDCQYSTSHPCFVSR-----PCLNGGTCHMLSRDTY 129
Query: 688 -CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQ 744
C C G+ G +C W C+ + C NG+ C+ + CKC G+TG Q
Sbjct: 130 ECTCQVGFTGKECQ-------WTDACL-SHPCANGSTCTTVANQFSCKCLTGFTG----Q 177
Query: 745 RCPLGFYGKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCEQKCPSGTYGYGCRQIC 802
+C +C + CQ+G C ++ G QC C GF G++C+ Y
Sbjct: 178 KCETDV--NECDIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSL-------YVPCAPS 228
Query: 803 DCLNNSTCDH---ITGTCYCSPGWKGARCDQ 830
C+N TC T C C PG++G+ C++
Sbjct: 229 PCVNGGTCRQTGDFTFECNCLPGFEGSTCER 259
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 234 bits (596), Expect = 5e-61
Identities = 248/881 (28%), Positives = 321/881 (36%), Gaps = 224/881 (25%)
Query: 15 LLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNWFKCTRHRV 74
LL + A +N ED H+ + ++ D+ YY++ + K R R
Sbjct: 161 LLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSATCN-----KFCRPRN 215
Query: 75 SYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKC--VHGRCIAPNTCQCEPGWGG 132
+ G T + ++ C + E C C +HG C P C+C GW G
Sbjct: 216 DF-----FGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQG 270
Query: 133 TNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCH 192
C C C +G+ P C+C + G C+ N C
Sbjct: 271 RFCD----------ECVPYPGCVHGSCVEP--WQCNCETNWGGLLCDKDL------NYCG 312
Query: 193 QRCQCQNGATCDHVTGE---CRCPPGYTGAFCEDLCPPGKHGPQCEQRC---PCQNGGVC 246
C NG TC + + C CP GY+G CE + E C PC NGG C
Sbjct: 313 SHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE----------KAEHACTSNPCANGGSC 362
Query: 247 HHVTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTC-DAATG-QCHCSPGY 302
H V EC CPSGW G C E C+ C GGTC D G +C C +
Sbjct: 363 HEVPSGFECHCPSGWSGPTCALDIDE------CASN-PCAAGGTCVDQVDGFECICPEQW 415
Query: 303 TGERCQDECPVGTYGVLCAETCQ---CVNGGKCYHVSGA--CLCEAGFAGERCEARL--- 354
G CQ L A C+ C+N C ++ G C C G+ G C +
Sbjct: 416 VGATCQ----------LDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDC 465
Query: 355 ---------CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET------ 399
C + + G +C CP H C ECA P SG C +
Sbjct: 466 RGQCQHGGTCKDLVNGYQC--VCPRGFGGRH-CELERDECASSPCHSGGLCEDLADGFHC 522
Query: 400 -CSPGFYGEACQ---QICS---CQNGADCDSVTGK--CTCAPGFKGIDCST---PCPLGT 447
C GF G C+ +C C+NGA C ++ G C C F G +CS PCP G
Sbjct: 523 HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA 582
Query: 448 YGINCSSRCGCKNDA-----------VCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCN 496
C GC +DA VC P G C + G + S C SG G C+
Sbjct: 583 ----CRVIDGCGSDAGPGMPGTAASGVCGP-HGRCVSQPGG---NFSCICDSGFTGTYCH 634
Query: 497 ------LTCQCLNGGAC-NTLDG-TCTCAPGWRGEKCE------LP-------------- 528
L C NGG C + +D C C GW GE C+ LP
Sbjct: 635 ENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVN 694
Query: 529 -----CQDGTYGLNCAER---CD---CSHADGCHPT--TGHCRCLPGWSGVHCDSVCAEG 575
C DG G C R CD CS+ C+ + T C C PGW G S CA
Sbjct: 695 DFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKG----STCAVA 750
Query: 576 RWGPNCSLPCYCKNGASC--SPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVH 633
+ +C LP C NG +C S C C G+ G TC H + P +
Sbjct: 751 K-NSSC-LPNPCVNGGTCVGSGASFSCICRDGWEGRTCT---------HNTNDCNPLPCY 799
Query: 634 SSGPCHHITGL----CDCLPGFTGALCN---EVCPSGRFGKNCAGICTCTN--NGTCNPI 684
+ G C + G+ C+C PGF G C + C S CA TC + NG
Sbjct: 800 NGGIC--VDGVNWFRCECAPGFAGPDCRINIDECQS----SPCAYGATCVDEING----- 848
Query: 685 DRSCQCYPGWIGSDCSQPC----------PPAHWGPNCIHTCNCHNGAFCSAYDGECKCT 734
C C PG G C + P G + + CN C DG C+
Sbjct: 849 -YRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNS-----CRCLDGRRDCS 902
Query: 735 PGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISGQC 774
W G P G+ AL QC G C + GQC
Sbjct: 903 KVWCGWK-----PCLLAGQPEALSAQCPLGQRCLEKAPGQC 938
Score = 211 bits (537), Expect = 3e-54
Identities = 214/772 (27%), Positives = 284/772 (36%), Gaps = 185/772 (23%)
Query: 139 CDGDHWGPHCTSRCQCKN---GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRC 195
CD +++ C C+ +N G G C G+ G C++ C Q C
Sbjct: 198 CDENYYSATCNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAV--------CKQGC 249
Query: 196 QCQNGATCDHVTGECRCPPGYTGAFCEDLCP-PG-KHGP--------------------- 232
+G V GECRC G+ G FC++ P PG HG
Sbjct: 250 NLLHGGCT--VPGECRCSYGWQGRFCDECVPYPGCVHGSCVEPWQCNCETNWGGLLCDKD 307
Query: 233 --QCEQRCPCQNGGVCHHVTGE---CSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGG 287
C PC NGG C + + C+CP G+ G C + ++ C NGG
Sbjct: 308 LNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCEK-------AEHACTSNPCANGG 360
Query: 288 TCDAATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCY-HVSG-ACL 340
+C +CHC G++G C DEC C GG C V G C+
Sbjct: 361 SCHEVPSGFECHCPSGWSGPTCALDIDECASNP----------CAAGGTCVDQVDGFECI 410
Query: 341 CEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE--CACKPGWSGLYCNE 398
C + G C+ L +C+ + PC N SC + G C C PGW G+ C+
Sbjct: 411 CPEQWVGATCQ-------LDANECEGK-PCL--NAFSCKNLIGGYYCDCIPGWKGINCHI 460
Query: 399 TCSPGFYGEACQQICSCQNGADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
+ C+ CQ+G C D V G +C C GF G C
Sbjct: 461 NVND------CRG--QCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-------------- 498
Query: 457 GCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLT---CQ---CLNGGACNTL 510
+++ SP C+ G C CP G G C + C+ C NG C L
Sbjct: 499 --RDECASSPCHSGGLCEDLADGFHC--HCPQGFSGPLCEVDVDLCEPSPCRNGARCYNL 554
Query: 511 DGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHC 568
+G C C + G+ C +P + G C DGC G PG G
Sbjct: 555 EGDYYCACPDDFGGKNCSVPREPCPGGA-------CRVIDGCGSDAG-----PGMPGTAA 602
Query: 569 DSVCA-EGRW--GPNCSLPCYCKNGAS---CSPDDGICECAPGFRGTTC-------QRIC 615
VC GR P + C C +G + C + C P G TC + C
Sbjct: 603 SGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFC 662
Query: 616 SPGFYGHRCSQTCPQCV----HSSGPCHHITG--LCDCLPGFTGALCNEVCPSGRFGKNC 669
G+ G C C+ HS G C+ + C C G+ G C+ S F C
Sbjct: 663 PSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH----SREF--QC 716
Query: 670 AGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC--S 725
TC+N GTC + C C PGW GS C+ +C+ C NG C S
Sbjct: 717 DAY-TCSNGGTCYDSGDTFRCACPPGWKGSTCA-----VAKNSSCLPN-PCVNGGTCVGS 769
Query: 726 AYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISG-QCTCRTGFMGR 783
C C GW G CT DC + C NG C D ++ +C C GF G
Sbjct: 770 GASFSCICRDGWEGRTCTHNT------NDCNPL-PCYNGGICVDGVNWFRCECAPGFAGP 822
Query: 784 HCE---QKCPSGTYGYGCRQICDCLNNSTC-DHITG-TCYCSPGWKGARCDQ 830
C +C S YG +TC D I G C C PG G RC +
Sbjct: 823 DCRINIDECQSSPCAYG----------ATCVDEINGYRCSCPPGRAGPRCQE 864
Score = 60.5 bits (145), Expect = 9e-09
Identities = 48/188 (25%), Positives = 71/188 (37%), Gaps = 41/188 (21%)
Query: 647 CLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPA 706
C + A CN+ C R + G TC G + C GW+G +C +
Sbjct: 198 CDENYYSATCNKFC---RPRNDFFGHYTCDQYG-------NKACMDGWMGKECKEAV--- 244
Query: 707 HWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD 766
C CN +G C+ GEC+C+ GW G +C + C C +G+
Sbjct: 245 -----CKQGCNLLHGG-CTV-PGECRCSYGWQGRFCDE----------CVPYPGCVHGSC 287
Query: 767 CDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDHITGT---CYCSPGW 823
+ QC C T + G C++ C C N TC + C C G+
Sbjct: 288 VE--PWQCNCETNWGGLLCDKDLNY------CGSHHPCTNGGTCINAEPDQYRCTCPDGY 339
Query: 824 KGARCDQA 831
G C++A
Sbjct: 340 SGRNCEKA 347
Score = 48.1 bits (113), Expect = 5e-05
Identities = 27/90 (30%), Positives = 40/90 (44%), Gaps = 15/90 (16%)
Query: 745 RCPLGFYGKDCALICQCQNGA----DCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQ 800
RC +Y C C+ +N CD G C G+MG+ C++ C+Q
Sbjct: 197 RCDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKEAV--------CKQ 247
Query: 801 ICDCLNNSTCDHITGTCYCSPGWKGARCDQ 830
C+ L+ + G C CS GW+G CD+
Sbjct: 248 GCNLLHGGCT--VPGECRCSYGWQGRFCDE 275
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 229 bits (585), Expect = 9e-60
Identities = 221/738 (29%), Positives = 270/738 (36%), Gaps = 181/738 (24%)
Query: 105 CVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC---N 161
CVP+ CVHG C+ P C CE WGG C + +C S C NG C
Sbjct: 276 CVPYPG--CVHGSCVEPWQCNCETNWGGLLCDKDLN------YCGSHHPCTNGGTCINAE 327
Query: 162 PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTG--ECRCPPGYTGA 219
P C C G+ G CE + E N C NG +C V EC CP G++G
Sbjct: 328 PDQYRCTCPDGYSGRNCE-KAEHACTSN------PCANGGSCHEVPSGFECHCPSGWSGP 380
Query: 220 FCE---DLCPPGKHGPQCEQRCPCQNGGVC-HHVTG-ECSCPSGWMGTVC--------GQ 266
C D C PC GG C V G EC CP W+G C GQ
Sbjct: 381 TCALDIDECASN----------PCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ 430
Query: 267 ----------------PCPEGRFGKNCS---QEC---QCHNGGTC-DAATG-QCHCSPGY 302
CP G G++C EC CH+GG C D A G CHC G+
Sbjct: 431 CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGF 490
Query: 303 TGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSG--ACLCEAGFAGERCEA--RLCPEG 358
+G C+ + LC E C NG +CY++ G C C F G+ C CP G
Sbjct: 491 SGPLCEVDVD------LC-EPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGG 543
Query: 359 LYGI--KCDKRCPCHLENTHS---CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQIC 413
+ C + T + C P G C +PG C C GF G C +
Sbjct: 544 ACRVIDGCGSDAGPGMPGTAASGVCGP-HGRCVSQPG-GNFSC--ICDSGFTGTYCHENI 599
Query: 414 S------CQNGADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCS 465
C+NG C D V +C C G++G C T P C SR C D V
Sbjct: 600 DDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTN-PNDCLPDPCHSRGRC-YDLV-- 655
Query: 466 PVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGE 523
D C C GW G C R F C+ C NGG C T C C PGW+G
Sbjct: 656 -NDFYCACDDGWKGKTCHSR------EFQCD-AYTCSNGGTCYDSGDTFRCACPPGWKGS 707
Query: 524 KCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCS- 582
C + C C + + C C GW G C + C+
Sbjct: 708 TCAVAKNSSCLPNPCVNGGTCVGSG----ASFSCICRDGWEGRTCTHNTND------CNP 757
Query: 583 LPCYCKNGASCSPDDGI----CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPC 638
LPCY NG C DG+ CECAPGF G C+ Q+ P C + +
Sbjct: 758 LPCY--NGGICV--DGVNWFRCECAPGFAGPDCRINIDE-------CQSSP-CAYGATCV 805
Query: 639 HHITGL-CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGS 697
I G C C PG G C EV GR +C + GT
Sbjct: 806 DEINGYRCSCPPGRAGPRCQEVIGFGR---------SCWSRGT----------------- 839
Query: 698 DCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCAL 757
P G + + CN C DG C+ W G P G+ AL
Sbjct: 840 -------PFPHGSSWVEDCNS-----CRCLDGRRDCSKVWCGWK-----PCLLAGQPEAL 882
Query: 758 ICQCQNGADC-DHISGQC 774
QC G C + GQC
Sbjct: 883 SAQCPLGQRCLEKAPGQC 900
Score = 199 bits (506), Expect = 1e-50
Identities = 204/723 (28%), Positives = 265/723 (36%), Gaps = 166/723 (22%)
Query: 181 RCEQGTYGNDCHQRCQCQNGA----TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQ 236
RC++ Y C++ C+ +N TCD G C G+ G C++ C+Q
Sbjct: 197 RCDENYYSATCNKFCRPRNDFFGHYTCDQY-GNKACMDGWMGKECKEAV--------CKQ 247
Query: 237 RCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQC 296
C +GG V GEC C GW +GRF C C +G + QC
Sbjct: 248 GCNLLHGGCT--VPGECRCSYGW----------QGRFCDECVPYPGCVHGSCVEP--WQC 293
Query: 297 HCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSG---ACLCEAGFAGERCEAR 353
+C + G C + C C NGG C + C C G++G CE
Sbjct: 294 NCETNWGGLLCDKDLNY------CGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNCE-- 345
Query: 354 LCPEGLYGIKCDKRC---PCHLENTHSCH--PMSGECACKPGWSGLYC--------NETC 400
K + C PC N SCH P EC C GWSG C + C
Sbjct: 346 ---------KAEHACTSNPC--ANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 401 SPGFYGEACQQI----CSCQN---GADC----DSVTGKC----TCAPGFKGIDCSTPCPL 445
+ G G Q+ C C GA C + G+C TC G C CP
Sbjct: 395 AAG--GTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCV--CPR 450
Query: 446 GTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLT---CQ-- 500
G G +C +++ SP C+ G C CP G G C + C+
Sbjct: 451 GFGGRHCELE---RDECASSPCHSGGLCEDLADGFHC--HCPQGFSGPLCEVDVDLCEPS 505
Query: 501 -CLNGGACNTLDGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHC 557
C NG C L+G C C + G+ C +P + G C DGC G
Sbjct: 506 PCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGA-------CRVIDGCGSDAG-- 556
Query: 558 RCLPGWSGVHCDSVCA-EGRW--GPNCSLPCYCKNGAS---CSPDDGICECAPGFRGTTC 611
PG G VC GR P + C C +G + C + C P G TC
Sbjct: 557 ---PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTC 613
Query: 612 -------QRICSPGFYGHRCSQTCPQCV----HSSGPCHHITG--LCDCLPGFTGALCNE 658
+ C G+ G C C+ HS G C+ + C C G+ G C+
Sbjct: 614 IDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH- 672
Query: 659 VCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCIHTC 716
S F C TC+N GTC + C C PGW GS C+ +C+
Sbjct: 673 ---SREF--QCDAY-TCSNGGTCYDSGDTFRCACPPGWKGSTCA-----VAKNSSCLPN- 720
Query: 717 NCHNGAFC--SAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISG- 772
C NG C S C C GW G CT DC + C NG C D ++
Sbjct: 721 PCVNGGTCVGSGASFSCICRDGWEGRTCTHNT------NDCNPL-PCYNGGICVDGVNWF 773
Query: 773 QCTCRTGFMGRHCE---QKCPSGTYGYGCRQICDCLNNSTC-DHITG-TCYCSPGWKGAR 827
+C C GF G C +C S YG +TC D I G C C PG G R
Sbjct: 774 RCECAPGFAGPDCRINIDECQSSPCAYG----------ATCVDEINGYRCSCPPGRAGPR 823
Query: 828 CDQ 830
C +
Sbjct: 824 CQE 826
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 220 bits (561), Expect = 5e-57
Identities = 178/583 (30%), Positives = 223/583 (38%), Gaps = 176/583 (30%)
Query: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE 183
C CEPGW G NCS P C C + I G C C GF G + C
Sbjct: 174 CVCEPGWKGPNCSE--------PECPGNCHLRGRC----IDGQCICDDGFTG----EDCS 217
Query: 184 QGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE-DLCPPGKHGPQCEQRCPC-Q 241
Q +DC+ + +C NG C C GY GA C ++CP PC +
Sbjct: 218 QLACPSDCNDQGKCVNGV--------CICFEGYAGADCSREICP-----------VPCSE 258
Query: 242 NGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPG 301
G C V G C C G+ G C +P C C +N G C +C C G
Sbjct: 259 EHGTC--VDGLCVCHDGFAGDDCNKPL--------CLNNC--YNRGRC--VENECVCDEG 304
Query: 302 YTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCP----- 356
+TGE C + ++C C + G+C ++G C CE GF GE C CP
Sbjct: 305 FTGEDCSE--------LICPN--DCFDRGRC--INGTCYCEEGFTGEDCGKPTCPHACHT 352
Query: 357 ------------EGLYGIKC-DKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE----- 398
EG G+ C +KRCP N C + G C C G++G C E
Sbjct: 353 QGRCEEGQCVCDEGFAGVDCSEKRCPADCHNRGRC--VDGRCECDDGFTGADCGELKCPN 410
Query: 399 -------------TCSPGFYGEACQQICSCQNGADCDS----VTGKCTCAPGFKGIDCS- 440
C G+ GE C Q+ C N DC S V GKC C GFKG DCS
Sbjct: 411 GCSGHGRCVNGQCVCDEGYTGEDCSQL-RCPN--DCHSRGRCVEGKCVCEQGFKGYDCSD 467
Query: 441 TPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIR-CPSGTWGFGCNLTC 499
CP +C C V+G C C G+ G DC R CP
Sbjct: 468 MSCP-----NDCHQHGRC--------VNGMCVCDDGYTGEDCRDRQCPR----------- 503
Query: 500 QCLNGGACNTLDGTCTCAPGWRGEKC-ELPCQDGTYGLNCAERCDCSHADGCHPTTGHCR 558
C N G C +DG C C G+ G C EL C + +G RC G C
Sbjct: 504 DCSNRGLC--VDGQCVCEDGFTGPDCAELSCPNDCHGQG---RC----------VNGQCV 548
Query: 559 CLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPG 618
C G+ G C C P C C DG C C GF G C +
Sbjct: 549 CHEGFMGKDCKE--------QRC--PSDCHGQGRCV--DGQCICHEGFTGLDCGQ----- 591
Query: 619 FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCP 661
+CP ++ G C ++G C C G++G C+EV P
Sbjct: 592 -------HSCPSDCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
Score = 219 bits (559), Expect = 9e-57
Identities = 181/596 (30%), Positives = 233/596 (39%), Gaps = 182/596 (30%)
Query: 283 CHNGGTCDAATGQCHCSPGYTGERCQD-ECPVGTYGVLCAETCQCVNGGKCYHVSGACLC 341
C G C C PG+ G C + ECP C G+C + G C+C
Sbjct: 161 CSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGN-----------CHLRGRC--IDGQCIC 207
Query: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCS 401
+ GF GE C CP C+ + C ++G C C G++G C+
Sbjct: 208 DDGFTGEDCSQLACPSD-----CNDQGKC----------VNGVCICFEGYAGADCSR--- 249
Query: 402 PGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKND 461
E C CS ++G D G C C GF G DC+ P L NC +R C
Sbjct: 250 -----EICPVPCSEEHGTCVD---GLCVCHDGFAGDDCNKPLCLN----NCYNRGRC--- 294
Query: 462 AVCSPVDGSCTCKAGWHGVDCS-IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGW 520
V+ C C G+ G DCS + CP+ C + G C ++GTC C G+
Sbjct: 295 -----VENECVCDEGFTGEDCSELICPN-----------DCFDRGRC--INGTCYCEEGF 336
Query: 521 RGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPN 580
GE C P C HA CH T G C VC EG G +
Sbjct: 337 TGEDCGKPT--------------CPHA--CH-TQGRCE--------EGQCVCDEGFAGVD 371
Query: 581 CS---LPCYCKNGASCSPDDGICECAPGFRGTTC------------------QRICSPGF 619
CS P C N C DG CEC GF G C Q +C G+
Sbjct: 372 CSEKRCPADCHNRGRCV--DGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGY 429
Query: 620 YGHRCSQT-CPQCVHSSGPCHHITGLCDCLPGFTGALCNEV-CPSGRFGKNCAGICTCTN 677
G CSQ CP HS G C + G C C GF G C+++ CP+ C
Sbjct: 430 TGEDCSQLRCPNDCHSRGRC--VEGKCVCEQGFKGYDCSDMSCPND-----------CHQ 476
Query: 678 NGTCNPIDRSCQCYPGWIGSDC-SQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPG 736
+G C ++ C C G+ G DC + CP +C N C DG+C C G
Sbjct: 477 HGRC--VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLC--VDGQCVCEDG 521
Query: 737 WTGLYCTQ-RCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHC-EQKCPSGTY 794
+TG C + CP DC +C NG QC C GFMG+ C EQ+CPS +
Sbjct: 522 FTGPDCAELSCP-----NDCHGQGRCVNG--------QCVCHEGFMGKDCKEQRCPSDCH 568
Query: 795 GYG-C---RQIC----------------DCLNNSTCDHITGTCYCSPGWKGARCDQ 830
G G C + IC DC N C ++G C C+ G+ G C +
Sbjct: 569 GQGRCVDGQCICHEGFTGLDCGQHSCPSDCNNLGQC--VSGRCICNEGYSGEDCSE 622
Score = 204 bits (519), Expect = 4e-52
Identities = 183/590 (31%), Positives = 227/590 (38%), Gaps = 178/590 (30%)
Query: 194 RCQCQNGATC--DHVTGECRCPPGYTGAF------CEDLCPPGKHGPQC-EQRCPCQNGG 244
R QC GA C TG P +G C +C PG GP C E CP G
Sbjct: 137 REQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECP----G 192
Query: 245 VCHHVTGECSCPSGWMGTVCGQP-CPEGRFGKNCSQ---ECQCHNGGTCDAATGQCHCSP 300
CH + G C + GQ C +G G++CSQ C++ G C G C C
Sbjct: 193 NCH-LRGRC---------IDGQCICDDGFTGEDCSQLACPSDCNDQGKC--VNGVCICFE 240
Query: 301 GYTGERCQDE-CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGL 359
GY G C E CPV C+E G C V G C+C GFAG+ C LC
Sbjct: 241 GYAGADCSREICPVP-----CSE-----EHGTC--VDGLCVCHDGFAGDDCNKPLCLNNC 288
Query: 360 YGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET------------------CS 401
Y N C + EC C G++G C+E C
Sbjct: 289 Y-------------NRGRC--VENECVCDEGFTGEDCSELICPNDCFDRGRCINGTCYCE 333
Query: 402 PGFYGEAC-QQIC--SCQNGADCDSVTGKCTCAPGFKGIDCSTP-CPLGTYGINCSSRCG 457
GF GE C + C +C C+ G+C C GF G+DCS CP +C +R
Sbjct: 334 EGFTGEDCGKPTCPHACHTQGRCEE--GQCVCDEGFAGVDCSEKRCPA-----DCHNRGR 386
Query: 458 CKNDAVCSPVDGSCTCKAGWHGVDCS-IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTC 516
C VDG C C G+ G DC ++CP+G G G +C+NG C C
Sbjct: 387 C--------VDGRCECDDGFTGADCGELKCPNGCSGHG-----RCVNG--------QCVC 425
Query: 517 APGWRGEKC------------------ELPCQDGTYGLNCAERCDCSHADGCHPTTGHCR 558
G+ GE C + C+ G G +C+ D S + CH H R
Sbjct: 426 DEGYTGEDCSQLRCPNDCHSRGRCVEGKCVCEQGFKGYDCS---DMSCPNDCHQ---HGR 479
Query: 559 CLPGWSGVHCDSVCAEGRWGPNC---SLPCYCKNGASCSPDDGICECAPGFRGTTC---- 611
C+ G VC +G G +C P C N C DG C C GF G C
Sbjct: 480 CVNGMC------VCDDGYTGEDCRDRQCPRDCSNRGLCV--DGQCVCEDGFTGPDCAELS 531
Query: 612 --------------QRICSPGFYGHRCS-QTCPQCVHSSGPCHHITGLCDCLPGFTGALC 656
Q +C GF G C Q CP H G C + G C C GFTG C
Sbjct: 532 CPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC--VDGQCICHEGFTGLDC 589
Query: 657 NE-VCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPP 705
+ CPS C N G C + C C G+ G DCS+ PP
Sbjct: 590 GQHSCPSD-----------CNNLGQC--VSGRCICNEGYSGEDCSEVSPP 626
Score = 167 bits (422), Expect = 7e-41
Identities = 133/416 (31%), Positives = 165/416 (39%), Gaps = 125/416 (30%)
Query: 94 CCPGFYESGEMC-VPHCADKCVH-GRCIAPNTCQCEPGWGGTNCSSA-CDGDHWGPHCTS 150
C GF +G+ C P C + C + GRC+ N C C+ G+ G +CS C D C
Sbjct: 270 CHDGF--AGDDCNKPLCLNNCYNRGRCVE-NECVCDEGFTGEDCSELICPND-----CFD 321
Query: 151 RCQCKNGALCNPITGACHCAAGFRG---------------WRCEDR---CEQGTYGNDCH 192
R +C I G C+C GF G RCE+ C++G G DC
Sbjct: 322 RGRC--------INGTCYCEEGFTGEDCGKPTCPHACHTQGRCEEGQCVCDEGFAGVDCS 373
Query: 193 Q-RC--QCQNGATCDHVTGECRCPPGYTGAFCEDL------------------CPPGKHG 231
+ RC C N C V G C C G+TGA C +L C G G
Sbjct: 374 EKRCPADCHNRGRC--VDGRCECDDGFTGADCGELKCPNGCSGHGRCVNGQCVCDEGYTG 431
Query: 232 PQCEQ-RCP--CQNGGVCHHVTGECSCPSGWMGTVCGQ-PCPEGRFGKNCSQECQCHNGG 287
C Q RCP C + G C V G+C C G+ G C CP CH G
Sbjct: 432 EDCSQLRCPNDCHSRGRC--VEGKCVCEQGFKGYDCSDMSCPN-----------DCHQHG 478
Query: 288 TCDAATGQCHCSPGYTGERCQD-ECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFA 346
C G C C GYTGE C+D +CP C N G C V G C+CE GF
Sbjct: 479 RC--VNGMCVCDDGYTGEDCRDRQCPR-----------DCSNRGLC--VDGQCVCEDGFT 523
Query: 347 GERCEARLCP-----------------EGLYGIKC-DKRCPCHLENTHSCHPMSGECACK 388
G C CP EG G C ++RCP C + G+C C
Sbjct: 524 GPDCAELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC--VDGQCICH 581
Query: 389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCP 444
G++GL C + P C N C V+G+C C G+ G DCS P
Sbjct: 582 EGFTGLDCGQHSCPS----------DCNNLGQC--VSGRCICNEGYSGEDCSEVSP 625
Score = 131 bits (329), Expect = 4e-30
Identities = 113/363 (31%), Positives = 141/363 (38%), Gaps = 109/363 (30%)
Query: 541 RCDCSHADGC--HPTTGHCRCLPGWSG------VHCDSVCAEGRWGPNCS---LPCYCKN 589
R C+ GC P TG P SG C VC G GPNCS P C
Sbjct: 137 REQCTAGAGCCLQPATGRLDTRPFCSGRGNFSTEGCGCVCEPGWKGPNCSEPECPGNCHL 196
Query: 590 GASCSPDDGICECAPGFRGTTCQR------------------ICSPGFYGHRCS-QTCP- 629
C DG C C GF G C + IC G+ G CS + CP
Sbjct: 197 RGRCI--DGQCICDDGFTGEDCSQLACPSDCNDQGKCVNGVCICFEGYAGADCSREICPV 254
Query: 630 QCVHSSGPCHHITGLCDCLPGFTGALCNE------------------VCPSGRFGKNCAG 671
C G C + GLC C GF G CN+ VC G G++C+
Sbjct: 255 PCSEEHGTC--VDGLCVCHDGFAGDDCNKPLCLNNCYNRGRCVENECVCDEGFTGEDCSE 312
Query: 672 -IC--TCTNNGTCNPIDRSCQCYPGWIGSDCSQP-CPPAHWGPNCIHTCNCHNGAFCSAY 727
IC C + G C I+ +C C G+ G DC +P CP A CH C
Sbjct: 313 LICPNDCFDRGRC--INGTCYCEEGFTGEDCGKPTCPHA-----------CHTQGRCE-- 357
Query: 728 DGECKCTPGWTGLYCTQ-RCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHC- 785
+G+C C G+ G+ C++ RCP C N C + G+C C GF G C
Sbjct: 358 EGQCVCDEGFAGVDCSEKRCP-----------ADCHNRGRC--VDGRCECDDGFTGADCG 404
Query: 786 EQKCPSGTYGYG-----------------CRQI-C--DCLNNSTCDHITGTCYCSPGWKG 825
E KCP+G G+G C Q+ C DC + C + G C C G+KG
Sbjct: 405 ELKCPNGCSGHGRCVNGQCVCDEGYTGEDCSQLRCPNDCHSRGRC--VEGKCVCEQGFKG 462
Query: 826 ARC 828
C
Sbjct: 463 YDC 465
Score = 130 bits (326), Expect = 9e-30
Identities = 96/297 (32%), Positives = 127/297 (42%), Gaps = 86/297 (28%)
Query: 91 KSQCCPGFY--ESGEMCVPH-CADKCVHGRCIAPNTCQCEPGWGGTNCSSA-CDGDHWGP 146
+ +C GF + GE+ P+ C+ HGRC+ C C+ G+ G +CS C D
Sbjct: 391 RCECDDGFTGADCGELKCPNGCSG---HGRCVN-GQCVCDEGYTGEDCSQLRCPND---- 442
Query: 147 HCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHV 206
C SR +C + G C C GF+G+ C D + NDCHQ +C NG
Sbjct: 443 -CHSRGRC--------VEGKCVCEQGFKGYDCSDM----SCPNDCHQHGRCVNGM----- 484
Query: 207 TGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCP--CQNGGVCHHVTGECSCPSGWMGTVC 264
C C GYTG C D ++CP C N G+C V G+C C G+ G C
Sbjct: 485 ---CVCDDGYTGEDCRD------------RQCPRDCSNRGLC--VDGQCVCEDGFTGPDC 527
Query: 265 GQ------------------PCPEGRFGKNCSQE---CQCHNGGTCDAATGQCHCSPGYT 303
+ C EG GK+C ++ CH G C GQC C G+T
Sbjct: 528 AELSCPNDCHGQGRCVNGQCVCHEGFMGKDCKEQRCPSDCHGQGRC--VDGQCICHEGFT 585
Query: 304 GERC-QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGL 359
G C Q CP C N G+C VSG C+C G++GE C P+ L
Sbjct: 586 GLDCGQHSCP-----------SDCNNLGQC--VSGRCICNEGYSGEDCSEVSPPKDL 629
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 218 bits (556), Expect = 2e-56
Identities = 212/760 (27%), Positives = 274/760 (36%), Gaps = 220/760 (28%)
Query: 103 EMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCN- 161
+ C+PH CVHG C P C CE WGG C + +C + C NG C+
Sbjct: 263 DKCIPHPG--CVHGICNEPWQCLCETNWGGQLCDKDLN------YCGTHQPCLNGGTCSN 314
Query: 162 --PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGA 219
P C C G+ G CE E + CH R C+ + + EC C PG+TG
Sbjct: 315 TGPDKYQCSCPEGYSGPNCE-IAEHACLSDPCHNRGSCKETS----LGFECECSPGWTGP 369
Query: 220 FCE---DLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVC--------GQ 266
C D C P C +GG C + +C CP W G C +
Sbjct: 370 TCSTNIDDCSPNN----------CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK 419
Query: 267 PCPE-----------------GRFGKNCS---QEC--QCHNGGTC-DAATG-QCHCSPGY 302
PC G G+NC +C QC N +C D G +C C PGY
Sbjct: 420 PCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGY 479
Query: 303 TGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSG--ACLCEAGFAGERCEARL--- 354
G+ C+ DEC + C+NGG C + CLC GF+G C+ +
Sbjct: 480 AGDHCERDIDEC----------ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYC 529
Query: 355 ---------------------CPEGLYGIKCD------KRCPCHLENT------------ 375
CPE G C + PC + ++
Sbjct: 530 EPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPE 589
Query: 376 -------------HSCHPMSG---ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGA 419
C SG C C G++G YC+E + C+ C+NG
Sbjct: 590 GVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENIND------CES-NPCRNGG 642
Query: 420 DC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPV--DGSCTCKA 475
C D V KC C+ G++G C T IN S+ C N C + D C CK
Sbjct: 643 TCIDGVNSYKCICSDGWEGAYCET-------NINDCSQNPCHNGGTCRDLVNDFYCDCKN 695
Query: 476 GWHGVDCSIR---CPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQ 530
GW G C R C T C NGG C C C GW G C +
Sbjct: 696 GWKGKTCHSRDSQCDEAT----------CNNGGTCYDEGDAFKCMCPGGWEGTTCNIARN 745
Query: 531 DGTYGLNCAERCDCSHADGCHPTTGH---CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYC 587
C H G G C C GW G +CA+ +CS P C
Sbjct: 746 SSCLPNPC-------HNGGTCVVNGESFTCVCKEGWEG----PICAQNT--NDCS-PHPC 791
Query: 588 KNGASCSPDDG--ICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL- 644
N +C D CECAPGF G C+ + C Q+ P C + I G
Sbjct: 792 YNSGTCVDGDNWYRCECAPGFAGPDCR------ININEC-QSSP-CAFGATCVDEINGYR 843
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGT-----CNPIDRSCQCYPGWIGSDC 699
C C PG +GA C EV G+ C + + +G CN +CQC G I C
Sbjct: 844 CVCPPGHSGAKCQEVS-----GRPCITMGSVIPDGAKWDDDCN----TCQCLNGRIA--C 892
Query: 700 SQP-CPPAHWGPNCIHT--CNCHNGAFC-SAYDGECKCTP 735
S+ C P P +H C +G C D +C P
Sbjct: 893 SKVWCGPR---PCLLHKGHSECPSGQSCIPILDDQCFVHP 929
Score = 192 bits (488), Expect = 2e-48
Identities = 209/793 (26%), Positives = 268/793 (33%), Gaps = 226/793 (28%)
Query: 182 CEQGTYGNDCHQRCQCQNGA----TCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQR 237
C+ YG C++ C+ ++ CD G C G+ G C C Q
Sbjct: 187 CDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAI--------CRQG 237
Query: 238 CPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNG---GTCDAATG 294
C ++G + G+C C GW G C +C H G G C+
Sbjct: 238 CSPKHGSC--KLPGDCRCQYGWQGLYC--------------DKCIPHPGCVHGICNEPW- 280
Query: 295 QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSG---ACLCEAGFAGERCE 351
QC C + G+ C + C C+NGG C + C C G++G CE
Sbjct: 281 QCLCETNWGGQLCDKDLNY------CGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE 334
Query: 352 ARLCPEGLYGIKCDKRC---PCHLENTHSCHPMS--GECACKPGWSGLYCN---ETCSPG 403
+ C PCH N SC S EC C PGW+G C+ + CSP
Sbjct: 335 I-----------AEHACLSDPCH--NRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPN 381
Query: 404 FYGEACQQICSCQNGADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKND 461
+C +G C D V G KC C P + G C C ++ C N
Sbjct: 382 ----------NCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDAN------ECEAK-PCVNA 424
Query: 462 AVCSPVDGS--CTCKAGWHGVDCSIR------------------------CPSGTWGFGC 495
C + S C C GW G +C I CP G G C
Sbjct: 425 KSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHC 484
Query: 496 NLTCQ------CLNGGAC-NTLDG-TCTCAPGWRGEKCEL--------PCQDGTYGLNCA 539
CLNGG C N ++ C C G+ G C+L PCQ+G N A
Sbjct: 485 ERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRA 544
Query: 540 ER--CDCSH---ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRW--GPNCSLPCYCKNGAS 592
C C C HCR P C A G C
Sbjct: 545 SDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGK 604
Query: 593 CSPDDG---ICECAPGFRGTTCQR-------------------------ICSPGFYGHRC 624
C G C+C GF GT C ICS G+ G C
Sbjct: 605 CKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYC 664
Query: 625 SQTCPQC----VHSSGPCHHITG--LCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNN 678
C H+ G C + CDC G+ G C+ + TC N
Sbjct: 665 ETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHS-------RDSQCDEATCNNG 717
Query: 679 GTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE---CKC 733
GTC + C C GW G+ C+ +C+ CHNG C +GE C C
Sbjct: 718 GTCYDEGDAFKCMCPGGWEGTTCN-----IARNSSCLPN-PCHNGGTC-VVNGESFTCVC 770
Query: 734 TPGWTGLYCTQR-------------------------CPLGFYGKDCAL-ICQCQN---- 763
GW G C Q C GF G DC + I +CQ+
Sbjct: 771 KEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCA 830
Query: 764 -GADC-DHISG-QCTCRTGFMGRHCEQKC--PSGTYGY----GCRQICDCLNNSTCDHIT 814
GA C D I+G +C C G G C++ P T G G + DC +TC +
Sbjct: 831 FGATCVDEINGYRCVCPPGHSGAKCQEVSGRPCITMGSVIPDGAKWDDDC---NTCQCLN 887
Query: 815 GTCYCSPGWKGAR 827
G CS W G R
Sbjct: 888 GRIACSKVWCGPR 900
Score = 178 bits (452), Expect = 2e-44
Identities = 197/752 (26%), Positives = 265/752 (35%), Gaps = 212/752 (28%)
Query: 9 LSFICLLLCHWIGTASPLNLED--PNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILNW 66
L F C W G N++D PN CSH + C D++N
Sbjct: 356 LGFECECSPGWTGPTCSTNIDDCSPNNCSHGGT--------------------CQDLVNG 395
Query: 67 FKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMC---VPHC-ADKCVHGR----C 118
FKC CP + +G+ C C A CV+ +
Sbjct: 396 FKCV------------------------CPPQW-TGKTCQLDANECEAKPCVNAKSCKNL 430
Query: 119 IAPNTCQCEPGWGGTNCS---SACDGDHWGPHCTSRCQCKNGALCNPITGA--CHCAAGF 173
IA C C PGW G NC + C G QC+N A C + C C G+
Sbjct: 431 IASYYCDCLPGWMGQNCDININDCLG-----------QCQNDASCRDLVNGYRCICPPGY 479
Query: 174 RGWRCE---DRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE---DLCPP 227
G CE D C N C CQN +C CP G++G C+ D C P
Sbjct: 480 AGDHCERDIDECA----SNPCLNGGHCQNEIN----RFQCLCPTGFSGNLCQLDIDYCEP 531
Query: 228 GKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQ--------PC--------- 268
PCQNG C++ + C CP + G C PC
Sbjct: 532 N----------PCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVA 581
Query: 269 ------PEGRFGKNCSQECQCHNGGTCDAATG---QCHCSPGYTGERCQDECPVGTYGVL 319
PEG S C H G C + +G C C+ G+TG C + +
Sbjct: 582 MASNDTPEG-VRYISSNVCGPH--GKCKSQSGGKFTCDCNKGFTGTYCHE-------NIN 631
Query: 320 CAETCQCVNGGKCYH--VSGACLCEAGFAGERCEARL--CPEGLYGIKCDKRCPCHLENT 375
E+ C NGG C S C+C G+ G CE + C + PCH N
Sbjct: 632 DCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQN----------PCH--NG 679
Query: 376 HSCHPMSGE--CACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADC--DSVTGKCTCA 431
+C + + C CK GW G C+ S C + +C NG C + KC C
Sbjct: 680 GTCRDLVNDFYCDCKNGWKGKTCHSRDS------QCDE-ATCNNGGTCYDEGDAFKCMCP 732
Query: 432 PGFKGIDCSTPCPLGTYGINCSSRC---GCKNDAVCSPVDG---SCTCKAGWHGVDCSIR 485
G++G C+ I +S C C N C V+G +C CK GW G C+
Sbjct: 733 GGWEGTTCN---------IARNSSCLPNPCHNGGTC-VVNGESFTCVCKEGWEGPICAQN 782
Query: 486 CPSGTWGFGCNLTCQCLNGGACNTLDG----TCTCAPGWRGEKCELPCQDGTYGLNCAER 541
C+ C N G C +DG C CAPG+ G C + +N +
Sbjct: 783 TND------CS-PHPCYNSGTC--VDGDNWYRCECAPGFAGPDCRI-------NINECQS 826
Query: 542 CDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGI 599
C+ C C C PG SG C V GR P ++ +GA D
Sbjct: 827 SPCAFGATCVDEINGYRCVCPPGHSGAKCQEV--SGR--PCITMGSVIPDGAKWDDDCNT 882
Query: 600 CECAPGFRGTTCQRI-CSPG----FYGHR---CSQTCPQCVHSSGPCHHITGLCDCLPGF 651
C+C G C ++ C P GH Q+C + H TG+ +C
Sbjct: 883 CQCLNG--RIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSS 940
Query: 652 TGALCNEVCPSGRFGKNCAGICTCTNNGTCNP 683
+ + + NCA I N +P
Sbjct: 941 LQPVKTKCTSDSYYQDNCANITFTFNKEMMSP 972
Score = 136 bits (343), Expect = 1e-31
Identities = 116/391 (29%), Positives = 151/391 (38%), Gaps = 99/391 (25%)
Query: 484 IRCPSGTWGFGCNLTCQ----CLNGGACNTLDGTCTCAPGWRGEKCELP-CQDGTYGLNC 538
+ C +GFGCN C+ AC+ +G TC GW G +C C+ G
Sbjct: 185 VTCDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAICRQG------ 237
Query: 539 AERCDCSHADGCHPTTGHCRCLPGWSGVHCD----------SVC-------AEGRWGPN- 580
CS G G CRC GW G++CD +C E WG
Sbjct: 238 -----CSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQL 292
Query: 581 -------CSLPCYCKNGASCS---PDDGICECAPGFRGTTCQRICSPGFYGHRC-SQTCP 629
C C NG +CS PD C C G+ G C+ H C S C
Sbjct: 293 CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCE------IAEHACLSDPC- 345
Query: 630 QCVHSSGPCHHITGL---CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDR 686
H+ G C T L C+C PG+TG C+ +C+ C++ GTC +
Sbjct: 346 ---HNRGSCKE-TSLGFECECSPGWTGPTCSTNI------DDCSP-NNCSHGGTCQDLVN 394
Query: 687 --SCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQ 744
C C P W G C P C++ +C N S Y C C PGW G Q
Sbjct: 395 GFKCVCPPQWTGKTCQLDANECEAKP-CVNAKSCKN-LIASYY---CDCLPGWMG----Q 445
Query: 745 RCPLGFYGKDCALICQCQNGADC-DHISG-QCTCRTGFMGRHCEQ---KCPSGTYGYGCR 799
C + DC + QCQN A C D ++G +C C G+ G HCE+ +C S
Sbjct: 446 NCDINI--NDC--LGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASN------- 494
Query: 800 QICDCLNNSTCDHITG--TCYCSPGWKGARC 828
CLN C + C C G+ G C
Sbjct: 495 ---PCLNGGHCQNEINRFQCLCPTGFSGNLC 522
Score = 129 bits (323), Expect = 2e-29
Identities = 146/588 (24%), Positives = 189/588 (32%), Gaps = 185/588 (31%)
Query: 399 TCSPGFYGEACQQICSCQNG----ADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSS 454
TC +YG C + C ++ CD G TC G+ G +C+ C
Sbjct: 186 TCDDYYYGFGCNKFCRPRDDFFGHYACDQ-NGNKTCMEGWMGPECNRAI--------CRQ 236
Query: 455 RCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCP-----------------SGTWGFG--- 494
C K+ + P G C C+ GW G+ C P WG
Sbjct: 237 GCSPKHGSCKLP--GDCRCQYGWQGLYCDKCIPHPGCVHGICNEPWQCLCETNWGGQLCD 294
Query: 495 -----CNLTCQCLNGGACNTLDG---TCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
C CLNGG C+ C+C G+ G CE+ + C R C
Sbjct: 295 KDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEI-AEHACLSDPCHNRGSCKE 353
Query: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCS-----------LPCYCK---NGAS 592
C C PGW+G C S + NCS C C G +
Sbjct: 354 TS----LGFECECSPGWTGPTC-STNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKT 408
Query: 593 CSPDDGICECAPGFRGTTCQRI-------CSPGFYGHRCSQTCPQCV---HSSGPCHHIT 642
C D CE P +C+ + C PG+ G C C+ + C +
Sbjct: 409 CQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLV 468
Query: 643 G--LCDCLPGFTGALC-------------------NEV------CPSGRFGKNC-AGICT 674
C C PG+ G C NE+ CP+G G C I
Sbjct: 469 NGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDY 528
Query: 675 CTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIH--------------TCN--- 717
C NP QCY SD CP + G NC H +C
Sbjct: 529 CEP----NPCQNGAQCYNR--ASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAM 582
Query: 718 ----------------CHNGAFCSAYDG---ECKCTPGWTGLYCTQRCPLGFYGKDCALI 758
C C + G C C G+TG YC + DC
Sbjct: 583 ASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENI------NDCE-S 635
Query: 759 CQCQNGADC-DHI-SGQCTCRTGFMGRHCE---QKCPSGTYGYG--CRQI-----CDCLN 806
C+NG C D + S +C C G+ G +CE C G CR + CDC N
Sbjct: 636 NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKN 695
Query: 807 ----------NSTCDHIT----GTCY---------CSPGWKGARCDQA 831
+S CD T GTCY C GW+G C+ A
Sbjct: 696 GWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIA 743
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 208 bits (530), Expect = 2e-53
Identities = 161/526 (30%), Positives = 203/526 (38%), Gaps = 120/526 (22%)
Query: 89 RRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP-- 146
RR SQ G Y+ G +C+ C+ G NC G + P
Sbjct: 377 RRASQSLDGTYQGGGVCI------------------DCQHHTTGVNCERCLPGFYRSPNH 418
Query: 147 -----HCTSRCQCKNG---ALCNPITGACHCAAGFRGWRCEDRCEQGTYG---------- 188
H RC C++ C +TG C+C F G RC D C +G G
Sbjct: 419 PLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTGFPSCYPTPSS 477
Query: 189 -NDCHQR---------CQCQ------NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGP 232
ND ++ C C N D G C C P + G CE LC PG +GP
Sbjct: 478 SNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE-LCAPGFYGP 536
Query: 233 QCEQRCPCQNGGV----CHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGT 288
C Q C C + GV C TG+C C G+ G C + C G F Q C C GT
Sbjct: 537 GC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGT 594
Query: 289 ----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGA---CLC 341
CD A G+C C P + G C D C G +G + C C G + GA C C
Sbjct: 595 LPEGCDEA-GRCLCQPEFAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRC 652
Query: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENT--HSCHPMSGECACKPGWSGLYCNET 399
G+ G C+ C G +G C C E + +C P SG+C+C+P +GL C +T
Sbjct: 653 RPGYTGTACQE--CSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRC-DT 709
Query: 400 CSPGFYG---------------------EACQQICSCQ---NGADCDSVTGKCTCAPGFK 435
C PG Y Q C C+ G CD C PGF
Sbjct: 710 CVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR------CKPGFW 763
Query: 436 GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG--- 492
G+ S P G +C R A C P G C CK G C+ C G +G
Sbjct: 764 GLSPSNP--EGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACA-SCKDGFFGLDQ 820
Query: 493 ---FGCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQD 531
FGC +C+C GGA C G C C P +G C P +D
Sbjct: 821 ADYFGCR-SCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
Score = 193 bits (491), Expect = 7e-49
Identities = 180/609 (29%), Positives = 223/609 (36%), Gaps = 122/609 (20%)
Query: 194 RCQCQNGATC-------DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVC 246
RC C A D +C C G C+ CP P N
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN---- 354
Query: 247 HHVTGEC-SCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGE 305
EC SC T C R + S + GG C C TG
Sbjct: 355 -----ECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVC------IDCQHHTTGV 403
Query: 306 RCQDECPVGTY--------GVLCAETCQCVNG---GKCYHVSGACLCEAGFAGERCEARL 354
C+ C G Y C C + G C ++G C C F+GERC+ +
Sbjct: 404 NCE-RCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCD--V 460
Query: 355 CPEGLYGIKC---------DKR-----------CPCHLENT--HSCH--PMSGECACKPG 390
C EG G D R C C T ++C P G C CKP
Sbjct: 461 CAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPN 520
Query: 391 WSGLYCNETCSPGFYGEACQQI-CSCQNGAD--CDSVTGKCTCAPGFKGIDCSTPCPLGT 447
+ G +C E C+PGFYG CQ CS AD CD TG+C C GF+G C C G
Sbjct: 521 FQGTHC-ELCAPGFYGPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDR-CAPGY 578
Query: 448 YGINCSSRCGCKNDAV----CSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLN 503
+ CGC C G C C+ + G C RC G GF C C
Sbjct: 579 FHFPLCQLCGCSPAGTLPEGCDEA-GRCLCQPEFAGPHCD-RCRPGYHGFPNCQACTCDP 636
Query: 504 GGACNTL---DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADG-----CHPTTG 555
GA + L G C C PG+ G C+ C G +G C CS A+G C P +G
Sbjct: 637 RGALDQLCGAGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCS-AEGSLHAACDPRSG 694
Query: 556 HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSP------DDGI------CECA 603
C C P +G+ CD+ C G + + P YC+ G SC P D + C C
Sbjct: 695 QCSCRPRVTGLRCDT-CVPGAY----NFP-YCEAG-SCHPAGLAPVDPALPEAQVPCMCR 747
Query: 604 PGFRGTTCQRICSPGFYG---------HRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGA 654
G +C R C PGF+G RCS + C TG C C P G
Sbjct: 748 AHVEGPSCDR-CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQ 806
Query: 655 LCNEVCPSGRFGKNCAGI-----CTCTNNG----TCNPIDRSCQCYPGWIGSDCSQPCPP 705
C C G FG + A C C G +C P C+C P G CS+P
Sbjct: 807 ACAS-CKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARD 865
Query: 706 AHWGPNCIH 714
H+ P+ H
Sbjct: 866 -HYLPDLHH 873
Score = 184 bits (466), Expect = 5e-46
Identities = 169/586 (28%), Positives = 214/586 (36%), Gaps = 123/586 (20%)
Query: 175 GWRC-----EDRCEQGTYGNDCHQRCQCQN---GATCDHVTGECRCPPGYT--------- 217
G RC D C+ + +C CQ+ G TCD RC PG+
Sbjct: 297 GGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCD------RCCPGFNQQPWKPATA 350
Query: 218 -------GAFCEDLCPPGKHGPQCEQRCPCQN-------GGVC----HHVTG-ECS-CPS 257
C + P+ ++R Q+ GGVC HH TG C C
Sbjct: 351 NSANECQSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLP 410
Query: 258 GWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYG 317
G+ + P + C+ E GTC+ TG+C+C P ++GERC D C G G
Sbjct: 411 GFYRSP-NHPLDSPHVCRRCNCESD-FTDGTCEDLTGRCYCRPNFSGERC-DVCAEGFTG 467
Query: 318 V-LCAET-------------------CQC----VNGGKCYHVS--GACLCEAGFAGERCE 351
C T C C G C G CLC+ F G CE
Sbjct: 468 FPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCE 527
Query: 352 ARLCPEGLYGIKCDKRCPCHLENT--HSCHPMSGECACKPGWSGLYCNETCSPGFYGEAC 409
LC G YG C + C C C P +G+C C+ G+ G C + C+PG++
Sbjct: 528 --LCAPGFYGPGC-QPCQCSSPGVADDRCDPDTGQCRCRVGFEGATC-DRCAPGYFHFPL 583
Query: 410 QQICSCQNGA----DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN----D 461
Q+C C CD G+C C P F G C C G +G C C D
Sbjct: 584 CQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDR-CRPGYHGFPNCQACTCDPRGALD 641
Query: 462 AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGG----ACNTLDGTCTCA 517
+C G C C+ G+ G C C G GF + C C G AC+ G C+C
Sbjct: 642 QLCG-AGGLCRCRPGYTGTACQ-ECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCSCR 699
Query: 518 PGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG-------HCRCLPGWSGVHCDS 570
P G +C+ C G Y E C H G P C C G CD
Sbjct: 700 PRVTGLRCD-TCVPGAYNFPYCEAGSC-HPAGLAPVDPALPEAQVPCMCRAHVEGPSCDR 757
Query: 571 VCAEGRWGPNCSLP-----CYCK------NGASCSPDDGICECAPGFRGTTCQRICSPGF 619
C G WG + S P C C A C P G C C P G C C GF
Sbjct: 758 -CKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACAS-CKDGF 815
Query: 620 YGHRCSQ--TCPQCVHSSG-----PCHHITGLCDCLPGFTGALCNE 658
+G + C C G C TG+C C P G C+E
Sbjct: 816 FGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Score = 172 bits (437), Expect = 1e-42
Identities = 156/598 (26%), Positives = 211/598 (35%), Gaps = 169/598 (28%)
Query: 367 RCPCHLENTHSCH------PMSGECACKPGWSGLYCNETCSPGFYGEACQ---------- 410
RC CH + +C P +C C+ G C+ C PGF + +
Sbjct: 299 RCVCH-GHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCC-PGFNQQPWKPATANSANEC 356
Query: 411 QICSCQNGA-DC------DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV 463
Q C+C A DC D + ++G C T G+NC +
Sbjct: 357 QSCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSP 416
Query: 464 CSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQC---LNGGACNTLDGTCTCAPGW 520
P+D C+ C C G C L G C C P +
Sbjct: 417 NHPLDSPHVCRR-----------------------CNCESDFTDGTCEDLTGRCYCRPNF 453
Query: 521 RGEKCELPCQDGTYGL-NCAE-------------------RCDCSHA----DGCH--PTT 554
GE+C++ C +G G +C CDCS A + C P
Sbjct: 454 SGERCDV-CAEGFTGFPSCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRV 512
Query: 555 GHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGA----SCSPDDGICECAPGFRGTT 610
G C C P + G HC+ +CA G +GP C PC C + C PD G C C GF G T
Sbjct: 513 GRCLCKPNFQGTHCE-LCAPGFYGPGCQ-PCQCSSPGVADDRCDPDTGQCRCRVGFEGAT 570
Query: 611 CQRICSPGFYGHRCSQTCPQCVHSSGP--CHHITGLCDCLPGFTGALCNEVCPSGRFGKN 668
C R C+PG++ Q C + P C G C C P F G C+ P N
Sbjct: 571 CDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHGFPN 628
Query: 669 CAGICTCTNNGTCNPIDRS---CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNG---- 721
C CTC G + + + C+C PG+ G+ C + P H P+C+ C+C
Sbjct: 629 CQA-CTCDPRGALDQLCGAGGLCRCRPGYTGTACQECSPGFHGFPSCV-PCHCSAEGSLH 686
Query: 722 AFCSAYDGECKCTPGWTGLYCT-------------------------------------- 743
A C G+C C P TGL C
Sbjct: 687 AACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLAPVDPALPEAQVPCMC 746
Query: 744 ---------QRCPLGFYG------KDCALICQCQ------NGADCDHISGQCTCRTGFMG 782
RC GF+G + C C C A+C +GQC C+ G
Sbjct: 747 RAHVEGPSCDRCKPGFWGLSPSNPEGCTR-CSCDLRGTLGGVAECQPGTGQCFCKPHVCG 805
Query: 783 RHCEQKCPSGTYG------YGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
+ C C G +G +GCR C C +C+ TG C C P +G C +
Sbjct: 806 QACAS-CKDGFFGLDQADYFGCRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSE 861
Score = 143 bits (360), Expect = 1e-33
Identities = 115/325 (35%), Positives = 136/325 (41%), Gaps = 61/325 (18%)
Query: 296 CHCSPGYTGERCQDECPVGTY----GVLCAET--CQCV-NGGKCYHVSGACL-CEAGFAG 347
C C Y G+ CQ EC G Y G+ CQC + +C SG C+ C+ G
Sbjct: 1831 CLCPASYRGDSCQ-ECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 348 ERCEARLCPEGLYGIKCDKR-----CPCHLEN-----THSCHPMSG--ECACKPGWSGLY 395
CE C G + D CPC L C G +C CKPG++G
Sbjct: 1890 AHCER--CQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGAS 1947
Query: 396 CNETCSPGFYGE------ACQQICSCQ-NG------ADCDSVTGKCT-CAPGFKGIDCST 441
C E C+PGF+G +CQ C C NG +DCD +TG C C G C
Sbjct: 1948 C-ERCAPGFFGNPLVLGSSCQP-CDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCEI 2005
Query: 442 PCPLGTYGI-----NCSSRCGCK--NDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGF- 493
C G YG NC+ RC C C P G C CKAG G C RC G +GF
Sbjct: 2006 -CAPGFYGNALLPGNCT-RCDCTPCGTEACDPHSGHCLCKAGVTGRRCD-RCQEGHFGFD 2062
Query: 494 ---GCNLTCQC---LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL--NCAERCDCS 545
GC C C G C+ G C C PG G +C C G +GL RC C
Sbjct: 2063 GCGGCR-PCACGPAAEGSECHPQSGQCHCRPGTMGPQCR-ECAPGYWGLPEQGCRRCQCP 2120
Query: 546 HADGCHPTTGHCRCLPGWSGVHCDS 570
C P TG C C PG SG CD+
Sbjct: 2121 -GGRCDPHTGRCNCPPGLSGERCDT 2144
Score = 132 bits (332), Expect = 2e-30
Identities = 126/460 (27%), Positives = 168/460 (36%), Gaps = 99/460 (21%)
Query: 423 SVTGKCTCAPGFKGIDCSTP---------CPLGTYGINCSSRCGCKNDAVCSPVDGSC-- 471
S+ G+C C D P C T G C C N P +
Sbjct: 295 SIGGRCVCHGHADACDAKDPTDPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSAN 354
Query: 472 ---TCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP 528
+C H DC + A +LDGT ++G +
Sbjct: 355 ECQSCNCYGHATDCYY-------------DPEVDRRRASQSLDGT------YQGGGVCID 395
Query: 529 CQDGTYGLNC--------------------AERCDCSH--ADG-CHPTTGHCRCLPGWSG 565
CQ T G+NC RC+C DG C TG C C P +SG
Sbjct: 396 CQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSG 455
Query: 566 VHCDSVCAEGRWG-PNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSP-GFYGHR 623
CD VCAEG G P+C S +D + P + C CS G G+
Sbjct: 456 ERCD-VCAEGFTGFPSCY-------PTPSSSNDTREQVLPAGQIVNCD--CSAAGTQGNA 505
Query: 624 CSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGT--- 680
C + P+ G C C P F G C E+C G +G C C C++ G
Sbjct: 506 CRKD-PR-----------VGRCLCKPNFQGTHC-ELCAPGFYGPGCQP-CQCSSPGVADD 551
Query: 681 -CNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN-GAFCSAYD--GECKCTPG 736
C+P C+C G+ G+ C + C P ++ C C G D G C C P
Sbjct: 552 RCDPDTGQCRCRVGFEGATCDR-CAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCLCQPE 610
Query: 737 WTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ---CTCRTGFMGRHCEQKCPSGT 793
+ G +C RC G++G C C D + G C CR G+ G C Q+C G
Sbjct: 611 FAGPHC-DRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLCRCRPGYTGTAC-QECSPGF 668
Query: 794 YGYGCRQICDCLN----NSTCDHITGTCYCSPGWKGARCD 829
+G+ C C ++ CD +G C C P G RCD
Sbjct: 669 HGFPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCD 708
Score = 123 bits (309), Expect = 9e-28
Identities = 112/358 (31%), Positives = 142/358 (39%), Gaps = 69/358 (19%)
Query: 157 GALCNPITGACHCAAGFRGWRCED------RCEQGTYGNDCHQRCQCQNGATCDHVTGEC 210
GAL + + C C A +RG C++ R +G + C CQC +
Sbjct: 1822 GALASNVE-LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVP-CQCHGHSD-------- 1871
Query: 211 RCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPE 270
RC PG C D C G CE+ CQ G V C S C PCP
Sbjct: 1872 RCLPG--SGVCVD-CQHNTEGAHCER---CQAGFVSSRDDPSAPCVS------C--PCPL 1917
Query: 271 GRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYG---VL--CAETCQ 325
N ++ C G T QC C PGY G C+ C G +G VL + C
Sbjct: 1918 SVPSNNFAEGCVLRGGRT------QCLCKPGYAGASCE-RCAPGFFGNPLVLGSSCQPCD 1970
Query: 326 CVNGGK-------CYHVSGACL-CEAGFAGERCEARLCPEGLYGI-----KCDKRCPCHL 372
C G C ++GAC C G RCE +C G YG C RC C
Sbjct: 1971 CSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRCE--ICAPGFYGNALLPGNCT-RCDCTP 2027
Query: 373 ENTHSCHPMSGECACKPGWSGLYCNETCSPGFYG-EACQ--QICSC---QNGADCDSVTG 426
T +C P SG C CK G +G C + C G +G + C + C+C G++C +G
Sbjct: 2028 CGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSG 2086
Query: 427 KCTCAPGFKGIDCSTPCPLGTYGI--NCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
+C C PG G C C G +G+ RC C C P G C C G G C
Sbjct: 2087 QCHCRPGTMGPQC-RECAPGYWGLPEQGCRRCQCPGGR-CDPHTGRCNCPPGLSGERC 2142
Score = 122 bits (307), Expect = 1e-27
Identities = 104/324 (32%), Positives = 131/324 (40%), Gaps = 62/324 (19%)
Query: 557 CRCLPGWSGVHCDSVCAEGRWGPNCSL------PCYCKNGAS-CSPDDGIC-ECAPGFRG 608
C C + G C CA G + L PC C + C P G+C +C G
Sbjct: 1831 CLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 609 TTCQRICSPGFYGHRCSQTCPQCVHSSGPC-------HHITGL--------CDCLPGFTG 653
C+R C GF R + P CV S PC + G C C PG+ G
Sbjct: 1890 AHCER-CQAGFVSSRDDPSAP-CV--SCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAG 1945
Query: 654 ALCNEVCPSGRFGK-----NCAGICTCTNNGT-------CNPIDRSCQ-CYPGWIGSDCS 700
A C E C G FG + C C+ NG C+P+ +C+ C G C
Sbjct: 1946 ASC-ERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLRHTTGPRC- 2003
Query: 701 QPCPPAHWG----PNCIHTCNCH--NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKD 754
+ C P +G P C+C C + G C C G TG C RC G +G D
Sbjct: 2004 EICAPGFYGNALLPGNCTRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DRCQEGHFGFD 2062
Query: 755 CALICQ------CQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG---YGCRQICDCL 805
C+ G++C SGQC CR G MG C ++C G +G GCR+ C C
Sbjct: 2063 GCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQC-RECAPGYWGLPEQGCRR-CQC- 2119
Query: 806 NNSTCDHITGTCYCSPGWKGARCD 829
CD TG C C PG G RCD
Sbjct: 2120 PGGRCDPHTGRCNCPPGLSGERCD 2143
Score = 115 bits (288), Expect = 2e-25
Identities = 81/216 (37%), Positives = 98/216 (45%), Gaps = 35/216 (16%)
Query: 124 CQCEPGWGGTNCSSACDGDHWGP----HCTSRCQCK-NG------ALCNPITGACH-CAA 171
C C+PG+ G +C G P C C NG + C+P+TGAC C
Sbjct: 1937 CLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTGACRGCLR 1996
Query: 172 GFRGWRCEDRCEQGTYGN-----DCHQRCQCQNGAT--CDHVTGECRCPPGYTGAFCEDL 224
G RCE C G YGN +C RC C T CD +G C C G TG C D
Sbjct: 1997 HTTGPRCEI-CAPGFYGNALLPGNC-TRCDCTPCGTEACDPHSGHCLCKAGVTGRRC-DR 2053
Query: 225 CPPGKHGPQCEQRC------PCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFG---K 275
C G G C P G CH +G+C C G MG C + C G +G +
Sbjct: 2054 CQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRE-CAPGYWGLPEQ 2112
Query: 276 NCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDEC 311
C + CQC GG CD TG+C+C PG +GERC D C
Sbjct: 2113 GC-RRCQCP-GGRCDPHTGRCNCPPGLSGERC-DTC 2145
Score = 99.4 bits (246), Expect = 2e-20
Identities = 70/223 (31%), Positives = 88/223 (39%), Gaps = 35/223 (15%)
Query: 633 HSSGPCHHITGLCDCLPGFTGALCNEVCPS-GRFGKNCAGICTCTNNG----TCNPIDRS 687
H + +HI+ P + C S F N A C C G TC P
Sbjct: 1403 HCAAQGYHIS------PSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQ 1456
Query: 688 CQCYPGWIGSDCSQPCPPAHWG-PNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRC 746
C C+ IG DCS+ C +WG PNC C+C C G+C C P C
Sbjct: 1457 CPCHAHVIGRDCSR-CATGYWGFPNC-RPCDC-GARLCDELTGQCICPPRTIPPDCLLCQ 1513
Query: 747 PLGFYGKDCALICQCQN------------GADCDHISGQCTCRTGFMGRHCEQKCPSGTY 794
P F C + C+ CD SGQC CR GR C+ C G +
Sbjct: 1514 PQTF---GCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDT-CSPGFH 1569
Query: 795 GYGCRQICDCLNNST----CDHITGTCYCSPGWKGARCDQAGV 833
GY + CDC T CD +TG CYC +G +CDQ +
Sbjct: 1570 GYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSL 1612
Score = 99.4 bits (246), Expect = 2e-20
Identities = 77/254 (30%), Positives = 96/254 (37%), Gaps = 47/254 (18%)
Query: 431 APGFKGIDC-STPCPLGTYGINCSSRCGCKN----DAVCSPVDGSCTCKAGWHGVDCSIR 485
+P + C + L + N + CGC C P G C C A G DCS R
Sbjct: 1412 SPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-R 1470
Query: 486 CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS 545
C +G WGF C C C+ L G C C P C L CQ T+G
Sbjct: 1471 CATGYWGFPNCRPCDC-GARLCDELTGQCICPPRTIPPDCLL-CQPQTFG---------- 1518
Query: 546 HADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCK-NGASCSPDDGICECAP 604
CHP G C NCS P + +C D G C+C P
Sbjct: 1519 ----CHPLVGCEEC--------------------NCSGPGIQELTDPTCDTDSGQCKCRP 1554
Query: 605 GFRGTTCQRICSPGFYGH-RCSQT-CPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPS 662
G C CSPGF+G+ RC C + + G C +TG C C G C++ C
Sbjct: 1555 NVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-CSL 1612
Query: 663 GRFGKNCAGICTCT 676
G F + A CT
Sbjct: 1613 GTFSLDAANPKGCT 1626
Score = 97.4 bits (241), Expect = 7e-20
Identities = 68/211 (32%), Positives = 84/211 (39%), Gaps = 33/211 (15%)
Query: 157 GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGY 216
G C P G C C A G C RC G +G + C C CD +TG+C CPP
Sbjct: 1447 GPTCEPFGGQCPCHAHVIGRDC-SRCATGYWGFPNCRPCDC-GARLCDELTGQCICPPRT 1504
Query: 217 TGAFCEDLCPPGKHGPQ----CEQRCPCQNGGV-------CHHVTGECSCPSGWMGTVCG 265
C LC P G CE+ C C G+ C +G+C C G C
Sbjct: 1505 IPPDCL-LCQPQTFGCHPLVGCEE-CNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRC- 1561
Query: 266 QPCPEGRFGKNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGVLCA 321
C G G + C CH GT CD TGQC+C G +C D+C +GT+ + A
Sbjct: 1562 DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKC-DQCSLGTFSLDAA 1620
Query: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEA 352
C C C A ERC +
Sbjct: 1621 NPKGCTR----------CFCFG--ATERCRS 1639
Score = 95.5 bits (236), Expect = 3e-19
Identities = 61/203 (30%), Positives = 87/203 (42%), Gaps = 24/203 (11%)
Query: 273 FGKNCSQECQCHN----GGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVN 328
F N ++ C CH G TC+ GQC C G C C G +G C C
Sbjct: 1430 FYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCS-RCATGYWGFPNCRPCDC-G 1487
Query: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYG----IKCDKRCPCHLENTH-----SCH 379
C ++G C+C C LC +G + C++ C C +C
Sbjct: 1488 ARLCDELTGQCICPPRTIPPDC--LLCQPQTFGCHPLVGCEE-CNCSGPGIQELTDPTCD 1544
Query: 380 PMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD----CDSVTGKCTCAPGFK 435
SG+C C+P +G C +TCSPGF+G + C C CD +TG+C C +
Sbjct: 1545 TDSGQCKCRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQ 1603
Query: 436 GIDCSTPCPLGTYGINCSSRCGC 458
G C C LGT+ ++ ++ GC
Sbjct: 1604 GPKCDQ-CSLGTFSLDAANPKGC 1625
Score = 87.0 bits (214), Expect = 9e-17
Identities = 78/255 (30%), Positives = 101/255 (39%), Gaps = 54/255 (21%)
Query: 599 ICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNE 658
+C C +RG +CQ C+PGFY +CV PC CLPG
Sbjct: 1830 LCLCPASYRGDSCQE-CAPGFYRDVKGLFLGRCV----PCQCHGHSDRCLPG-------- 1876
Query: 659 VCPSGRFGKNCAGICT-CTNNGTCNPIDRSCQCYPGWIGS--DCSQPCPPAHWGPNCIHT 715
+G+C C +N +R C G++ S D S PC P + +
Sbjct: 1877 -----------SGVCVDCQHNTEGAHCER---CQAGFVSSRDDPSAPCVSCPC-PLSVPS 1921
Query: 716 CNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ------NG----- 764
N G +C C PG+ G C +RC GF+G L CQ NG
Sbjct: 1922 NNFAEGCVLRGGRTQCLCKPGYAGASC-ERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLL 1980
Query: 765 -ADCDHISGQCT-CRTGFMGRHCEQKCPSGTYGYG-----CRQICDCLNNST--CDHITG 815
+DCD ++G C C G CE C G YG C + CDC T CD +G
Sbjct: 1981 FSDCDPLTGACRGCLRHTTGPRCEI-CAPGFYGNALLPGNCTR-CDCTPCGTEACDPHSG 2038
Query: 816 TCYCSPGWKGARCDQ 830
C C G G RCD+
Sbjct: 2039 HCLCKAGVTGRRCDR 2053
Score = 85.5 bits (210), Expect = 3e-16
Identities = 64/206 (31%), Positives = 82/206 (39%), Gaps = 31/206 (15%)
Query: 189 NDCHQRCQCQN----GATCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNG 243
N+ + C C G TC+ G+C C G C C G G P C PC G
Sbjct: 1432 NNGARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR-CATGYWGFPNCR---PCDCG 1487
Query: 244 G-VCHHVTGECSCPSGWMGTVC--GQPCPEGRFGKNCSQECQCHNGG-------TCDAAT 293
+C +TG+C CP + C QP G +EC C G TCD +
Sbjct: 1488 ARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDS 1547
Query: 294 GQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGK----CYHVSGACLCEAGFAGER 349
GQC C P TG RC D C G +G C C G C ++G C C+ G +
Sbjct: 1548 GQCKCRPNVTGRRC-DTCSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
Query: 350 CEARLCPEGLYGI-----KCDKRCPC 370
C+ C G + + K RC C
Sbjct: 1607 CDQ--CSLGTFSLDAANPKGCTRCFC 1630
Score = 83.2 bits (204), Expect = 1e-15
Identities = 69/221 (31%), Positives = 86/221 (38%), Gaps = 29/221 (13%)
Query: 101 SGEMCVPHCADKCVHGRCIAPNTCQCEPG-WGGTNCSSACDGDHWGPHCTSRCQCK---- 155
+G C P H I + +C G WG NC G T +C C
Sbjct: 1446 TGPTCEPFGGQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTI 1505
Query: 156 --NGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCP 213
+ LC P T CH G CE+ C G Q TCD +G+C+C
Sbjct: 1506 PPDCLLCQPQTFGCHPLVG-----CEE-CNCSGPG------IQELTDPTCDTDSGQCKCR 1553
Query: 214 PGYTGAFCEDLCPPGKHG-PQCEQRCPCQNG----GVCHHVTGECSCPSGWMGTVCGQPC 268
P TG C D C PG HG P+C + C C GVC +TG+C C G C Q C
Sbjct: 1554 PNVTGRRC-DTCSPGFHGYPRC-RPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ-C 1610
Query: 269 PEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQD 309
G F + + C C AT +C S YT + D
Sbjct: 1611 SLGTFSLDAANPKGC-TRCFCFGATERCR-SSSYTRQEFVD 1649
Score = 74.3 bits (181), Expect = 6e-13
Identities = 54/190 (28%), Positives = 70/190 (36%), Gaps = 28/190 (14%)
Query: 321 AETCQC----VNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH 376
A C C G C G C C A G C C G +G + C C
Sbjct: 1435 ARPCGCHEVGATGPTCEPFGGQCPCHAHVIGRDCSR--CATGYWGFPNCRPCDC---GAR 1489
Query: 377 SCHPMSGECACKPGWSGLYCNETCSPGFYG----EACQQICSCQNGA-------DCDSVT 425
C ++G+C C P C C P +G C++ C+C CD+ +
Sbjct: 1490 LCDELTGQCICPPRTIPPDCL-LCQPQTFGCHPLVGCEE-CNCSGPGIQELTDPTCDTDS 1547
Query: 426 GKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN----DAVCSPVDGSCTCKAGWHGVD 481
G+C C P G C T C G +G C C VC P+ G C CK G
Sbjct: 1548 GQCKCRPNVTGRRCDT-CSPGFHGYPRCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPK 1606
Query: 482 CSIRCPSGTW 491
C +C GT+
Sbjct: 1607 CD-QCSLGTF 1615
Score = 54.3 bits (129), Expect = 6e-07
Identities = 42/131 (32%), Positives = 51/131 (38%), Gaps = 24/131 (18%)
Query: 89 RRKSQCCPGFY--ESGEMCVPHCADKCVHGRCIAPNT--CQCEPGWGGTNCSSACDGDHW 144
RR +C G + + C P G P + C C PG G C G +W
Sbjct: 2049 RRCDRCQEGHFGFDGCGGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPG-YW 2107
Query: 145 G--PHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQ--------GTYGNDCHQR 194
G RCQC G C+P TG C+C G G RC D C Q G G+ H
Sbjct: 2108 GLPEQGCRRCQCPGGR-CDPHTGRCNCPPGLSGERC-DTCSQQHQVPVPGGPVGHSIH-- 2163
Query: 195 CQCQNGATCDH 205
C+ CDH
Sbjct: 2164 CE-----VCDH 2169
Score = 40.4 bits (93), Expect = 0.010
Identities = 36/130 (27%), Positives = 49/130 (37%), Gaps = 23/130 (17%)
Query: 93 QCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWG---------GTNCSSACDG-- 141
+C PGF+ C R +C+PG G G C+S DG
Sbjct: 757 RCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFF 816
Query: 142 -----DHWGPHCTSRCQCK-NGAL---CNPITGACHCAAGFRGWRCEDRCEQGTYGNDCH 192
D++G C S C+C GAL C P TG C C +G C + + H
Sbjct: 817 GLDQADYFG--CRS-CRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYLPDLHH 873
Query: 193 QRCQCQNGAT 202
R + + AT
Sbjct: 874 LRLELEEAAT 883
Score = 40.0 bits (92), Expect = 0.013
Identities = 36/130 (27%), Positives = 48/130 (36%), Gaps = 24/130 (18%)
Query: 731 CKCTPGWTGLYCTQRCPLGFYGKDCALI------CQCQNGAD-CDHISGQCT-CRTGFMG 782
C C + G C Q C GFY L CQC +D C SG C C+ G
Sbjct: 1831 CLCPASYRGDSC-QECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEG 1889
Query: 783 RHCEQKCPSGTYGYGCRQICDCLN---------NSTCDHIT-----GTCYCSPGWKGARC 828
HCE +C +G C++ N+ + C C PG+ GA C
Sbjct: 1890 AHCE-RCQAGFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRGGRTQCLCKPGYAGASC 1948
Query: 829 DQAGVIIVGN 838
++ GN
Sbjct: 1949 ERCAPGFFGN 1958
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 206 bits (524), Expect = 1e-52
Identities = 199/705 (28%), Positives = 255/705 (36%), Gaps = 188/705 (26%)
Query: 109 CADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA-- 166
C D CV G TC C G+ G C + C S+ C+NG C +
Sbjct: 284 CIDDCVTGN--PSYTCSCLSGFTGRRCHLDVN------ECASQ-PCQNGGTCTHGINSFR 334
Query: 167 CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPPGYTGAFCE-- 222
C C AGF G CE T + C + +CQ+G C G C C GYTGA CE
Sbjct: 335 CQCPAGFGGPTCE------TAQSPCDTK-ECQHGGQCQVENGSAVCVCQAGYTGAACEMD 387
Query: 223 -DLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVC---GQPCPEGRFGKN 276
D C P PC NGG C + G C C + G C P P+
Sbjct: 388 VDDCSPD----------PCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPD------ 431
Query: 277 CSQECQCHNGGTC-DAATGQ-CHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH 334
CHNGGTC DA G C C G+ G C++ P + C+C NGG+C
Sbjct: 432 ACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVP---------DDCECRNGGRCLG 482
Query: 335 VSGA-CLCEAGFAGERCEARL----------CPEGLYGIK--CDKRCPCHLENTHSCHPM 381
+ C C GF G CE + CP+G Y ++ C CH ++ S H +
Sbjct: 483 ANTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNAS-HSL 541
Query: 382 SGECACKPGWSGLYCNE-------TCSPGFYGEACQQ----ICS---CQNGADCDSVTGK 427
C P ++G C+ C GF+G+ C++ +CS C+NG C G+
Sbjct: 542 PSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGE 601
Query: 428 --CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCS 483
C+C F G C P +C+S C N C G C C G+ G C
Sbjct: 602 YHCSCPYRFTGRHCEIGKP-----DSCASG-PCHNGGTCFHYIGKYKCDCPPGFSGRHCE 655
Query: 484 IRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKC--ELPCQ--------- 530
I PS + C+NGG C D C C G+ G +C E+ C
Sbjct: 656 I-APSPCF------RSPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHAT 708
Query: 531 ----------------DGTYGLNCAERC------------------------DCSHADGC 550
D Y L+ R C H C
Sbjct: 709 LRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSC 768
Query: 551 HPTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRG 608
C C G+ G HC+ E R P C+NG SC G C
Sbjct: 769 QDRVAGYLCLCSTGYEGAHCELERDECRAHP-------CRNGGSCRNLPGAYVCR----- 816
Query: 609 TTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKN 668
C GF G C C S PC H G C+ G LC VCP FG +
Sbjct: 817 ------CPAGFVGVHCETEVDAC--DSSPCQH-GGRCE--SGGGAYLC--VCPESFFGYH 863
Query: 669 CAGI------CTCTNNGTC--NPIDRSCQCYPGWIGSDCSQPCPP 705
C + C G C + SC C G+ G DC++ P
Sbjct: 864 CETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 199 bits (505), Expect = 2e-50
Identities = 197/693 (28%), Positives = 242/693 (34%), Gaps = 215/693 (31%)
Query: 283 CHNGGTC--DAATGQ----CHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCY 333
C NGG C D TG C C G+TG RC +EC ++ CQ NGG C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC--------ASQPCQ--NGGTCT 327
Query: 334 HV--SGACLCEAGFAGERCEARLCPEGLYGIKCD-KRCP----CHLENTHSCHPMSGECA 386
H S C C AGF G CE P CD K C C +EN S C
Sbjct: 328 HGINSFRCQCPAGFGGPTCETAQSP-------CDTKECQHGGQCQVENG------SAVCV 374
Query: 387 CKPGWSGLYCN---ETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKGIDCST 441
C+ G++G C + CSP C NG C + G C CA FKG+ C T
Sbjct: 375 CQAGYTGAACEMDVDDCSPD----------PCLNGGSCVDLVGNYTCLCAEPFKGLRCET 424
Query: 442 ---PCPLGTYGINCSSRCGCKNDAVCSPVDGS--CTCKAGWHGVDCSIRCPSGTWGFGCN 496
P P + C N C D C C G+ G+DC R P
Sbjct: 425 GDHPVP------DACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD------- 471
Query: 497 LTCQCLNGGACNTLDGT-CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG 555
C+C NGG C + T C C G+ G CE + C C C G
Sbjct: 472 --CECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT----AMPCNMNTQCPDGGYCMEHGG 525
Query: 556 HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFRGTTCQR 613
C+ H D + P S PC+ NG SC D CEC GF G C++
Sbjct: 526 SYLCV-----CHTDHNASHSLPSPCDSDPCF--NGGSCDAHDDSYTCECPRGFHGKHCEK 578
Query: 614 ----ICSPG----------------------FYGHRCSQTCPQCVHSSGPCH------HI 641
+CS G F G C P +SGPCH H
Sbjct: 579 ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSC-ASGPCHNGGTCFHY 637
Query: 642 TGL--CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS--CQCYPGWIGS 697
G CDC PGF+G C E+ PS F C N GTC D C C G++G
Sbjct: 638 IGKYKCDCPPGFSGRHC-EIAPSPCFRS------PCVNGGTCEDRDTDFFCHCQAGYMGR 690
Query: 698 ------DCSQPCPPAHW------------------------GPNCIHTCNCHN----GAF 723
DC P H P+ I C H
Sbjct: 691 RCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQ 750
Query: 724 CSAYDGECKCTPGWTGLYCTQR-------CPLGFYGKDCALI---CQ---CQNGADCDHI 770
C D EC+ P G C R C G+ G C L C+ C+NG C ++
Sbjct: 751 CLEID-ECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNL 809
Query: 771 SGQ--CTCRTGFMGRHCEQK-------------------------CPSGTYGYGCRQICD 803
G C C GF+G HCE + CP +GY C + D
Sbjct: 810 PGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVSD 869
Query: 804 CLNNSTC--------DHITGTCYCSPGWKGARC 828
+S C + + +C C G+ G C
Sbjct: 870 PCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDC 902
Score = 151 bits (381), Expect = 4e-36
Identities = 140/515 (27%), Positives = 183/515 (35%), Gaps = 165/515 (32%)
Query: 100 ESGEMCVPH-CADKCVH--GRCIAPN---TCQCEPGWGGTNCSSACDGDHWGPHCTSRCQ 153
E+G+ VP C H G C+ + C+C G+ G +C D C+
Sbjct: 423 ETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDD---------CE 473
Query: 154 CKNGALC-NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC--------- 203
C+NG C T C C GF G CE C+ QC +G C
Sbjct: 474 CRNGGRCLGANTTLCQCPLGFFGLLCEFEIT----AMPCNMNTQCPDGGYCMEHGGSYLC 529
Query: 204 ----DH-----VTGECRCPPGYTGAFCEDL-------CPPGKHGPQCEQR----C---PC 240
DH + C P + G C+ CP G HG CE+ C PC
Sbjct: 530 VCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPC 589
Query: 241 QNGGVCHHVTGE--CSCPSGWMGTVC--GQP--CPEGRFGKNCSQECQCHNGGTCDAATG 294
+NGG C GE CSCP + G C G+P C G CHNGGTC G
Sbjct: 590 RNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASG----------PCHNGGTCFHYIG 639
Query: 295 Q--CHCSPGYTGERCQDECPVGTYGVLCAETC---QCVNGGKCYH--VSGACLCEAGFAG 347
+ C C PG++G C+ + C CVNGG C C C+AG+ G
Sbjct: 640 KYKCDCPPGFSGRHCE----------IAPSPCFRSPCVNGGTCEDRDTDFFCHCQAGYMG 689
Query: 348 ERCEARL---------------------------CPEGLYGIKCDKRCP-CHLENTHSCH 379
RC+A + C G Y + R C S
Sbjct: 690 RRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRG-YSLSAPSRIRVCQPHGVWSEP 748
Query: 380 PMS---GECACKPGWSGLYCNET-------CSPGFYGEACQ------QICSCQNGADCDS 423
P EC +P G C + CS G+ G C+ + C+NG C +
Sbjct: 749 PQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRN 808
Query: 424 VTGK--CTCAPGFKGIDCSTP-------------------------CPLGTYGINC---- 452
+ G C C GF G+ C T CP +G +C
Sbjct: 809 LPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPESFFGYHCETVS 868
Query: 453 ----SSRCGCKNDAVCSPVDGSCTCKAGWHGVDCS 483
SS CG + + S SCTCK G+ G DC+
Sbjct: 869 DPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCA 903
Score = 100 bits (249), Expect = 8e-21
Identities = 113/443 (25%), Positives = 142/443 (32%), Gaps = 132/443 (29%)
Query: 15 LLCHWIGTASPLNLE----DPNVC-SHWESYSVT------VQESYPHPFDQIYYTSCTDI 63
LLC + TA P N+ D C H SY S P P D
Sbjct: 497 LLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDS------DPC 550
Query: 64 LNWFKCTRHRVSYRTAYR---HGEKTMYRRKSQCCPGFYESGEMCVP-----HCA----- 110
N C H SY HG+ R C G +G C HC+
Sbjct: 551 FNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 610
Query: 111 ----------DKCVHGRC---------IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSR 151
D C G C I C C PG+ G +C A P R
Sbjct: 611 TGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIA-------PSPCFR 663
Query: 152 CQCKNGALCNP--ITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQ------------- 196
C NG C CHC AG+ G RC+ + G H +
Sbjct: 664 SPCVNGGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYA 723
Query: 197 CQNGATCDHVT--------------------GECRCPPGYTGAFCED-------LCPPGK 229
C G + + ECR P G C+D LC G
Sbjct: 724 CDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGY 783
Query: 230 HGPQCE---QRC---PCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKNCSQEC 281
G CE C PC+NGG C ++ G C CP+G++G C +
Sbjct: 784 EGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEV-------DACDSS 836
Query: 282 QCHNGGTCDAATGQ--CHCSPGYTGERCQ---DEC---PVGTYGVLCAETCQCVNGGKCY 333
C +GG C++ G C C + G C+ D C P G G C NG
Sbjct: 837 PCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGY-----CLASNG---- 887
Query: 334 HVSGACLCEAGFAGERCEARLCP 356
S +C C+ G+ GE C L P
Sbjct: 888 --SHSCTCKVGYTGEDCAKELFP 908
Score = 41.6 bits (96), Expect = 0.004
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 8/61 (13%)
Query: 587 CKNGASCSP--DDGICECAPGFRGTTCQRICSPGFYGHRC----SQTCPQCVHSSGPCHH 640
C+NG +C P D C+C PGF+G C+ C C S+T V G CHH
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELACIK--VSRPCTRLFSETKAFPVWEGGVCHH 1373
Query: 641 I 641
+
Sbjct: 1374 V 1374
Score = 41.2 bits (95), Expect = 0.006
Identities = 27/71 (38%), Positives = 33/71 (46%), Gaps = 7/71 (9%)
Query: 271 GRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQDECPVGTYGV--LCAET--C 324
G NCS+ C NGGTC A C C PG+ G RC+ C + L +ET
Sbjct: 1305 GNVPGNCSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAF 1363
Query: 325 QCVNGGKCYHV 335
GG C+HV
Sbjct: 1364 PVWEGGVCHHV 1374
Score = 40.0 bits (92), Expect = 0.013
Identities = 28/75 (37%), Positives = 32/75 (42%), Gaps = 15/75 (20%)
Query: 185 GTYGNDCHQRCQCQNGATCDHVTG----ECRCPPGYTGAFCEDLCPPGKHGPQC------ 234
G +C + CQNG TC V G C C PG+ G CE C K C
Sbjct: 1305 GNVPGNCSEN-PCQNGGTC--VPGADAHSCDCGPGFKGRRCELACI--KVSRPCTRLFSE 1359
Query: 235 EQRCPCQNGGVCHHV 249
+ P GGVCHHV
Sbjct: 1360 TKAFPVWEGGVCHHV 1374
Score = 35.8 bits (81), Expect = 0.24
Identities = 14/31 (45%), Positives = 18/31 (58%), Gaps = 2/31 (6%)
Query: 501 CLNGGAC--NTLDGTCTCAPGWRGEKCELPC 529
C NGG C +C C PG++G +CEL C
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 34.3 bits (77), Expect = 0.69
Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Query: 146 PHCTSRCQCKNGALCNPITGA--CHCAAGFRGWRCEDRC 182
P S C+NG C P A C C GF+G RCE C
Sbjct: 1308 PGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC 1346
Score = 33.5 bits (75), Expect = 1.2
Identities = 16/35 (45%), Positives = 17/35 (48%), Gaps = 4/35 (11%)
Query: 409 CQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPC 443
CQ +C GAD S C C PGFKG C C
Sbjct: 1316 CQNGGTCVPGADAHS----CDCGPGFKGRRCELAC 1346
Score = 32.7 bits (73), Expect = 2.0
Identities = 24/80 (30%), Positives = 27/80 (33%), Gaps = 19/80 (23%)
Query: 668 NCAGICT---CTNNGTCNP--IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGA 722
N G C+ C N GTC P SC C PG+ G C C
Sbjct: 1306 NVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKV--------------SR 1351
Query: 723 FCSAYDGECKCTPGWTGLYC 742
C+ E K P W G C
Sbjct: 1352 PCTRLFSETKAFPVWEGGVC 1371
Score = 31.6 bits (70), Expect = 4.5
Identities = 30/112 (26%), Positives = 43/112 (38%), Gaps = 25/112 (22%)
Query: 320 CAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHS 377
C+E C NGG C + A C C GF G RCE + C ++ +
Sbjct: 1311 CSEN-PCQNGGTCVPGADAHSCDCGPGFKGRRCE----------LAC-------IKVSRP 1352
Query: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCT 429
C + E P W G C+ + Q IC ++ C+S + K T
Sbjct: 1353 CTRLFSETKAFPVWEGGVCHHVYKRVY--RVHQDICFKES---CESTSLKKT 1399
Score = 31.6 bits (70), Expect = 4.5
Identities = 15/33 (45%), Positives = 16/33 (48%), Gaps = 6/33 (18%)
Query: 761 CQNGADCDHISG----QCTCRTGFMGRHCEQKC 789
CQNG C + G C C GF GR CE C
Sbjct: 1316 CQNGGTC--VPGADAHSCDCGPGFKGRRCELAC 1346
Score = 31.2 bits (69), Expect = 5.9
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 10/58 (17%)
Query: 82 HGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSAC 139
HG K + C ++G CVP AD ++C C PG+ G C AC
Sbjct: 1299 HGSKDIGNVPGNCSENPCQNGGTCVPG-ADA---------HSCDCGPGFKGRRCELAC 1346
Score = 30.8 bits (68), Expect = 7.7
Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 6/51 (11%)
Query: 804 CLNNSTCDHITG----TCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALP 850
C N TC + G +C C PG+KG RC+ A + + L + A P
Sbjct: 1316 CQNGGTC--VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFP 1364
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 205 bits (522), Expect = 2e-52
Identities = 124/362 (34%), Positives = 152/362 (41%), Gaps = 62/362 (17%)
Query: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
S + + C G++ D P+ C C+ D VC G C CK G+ G C
Sbjct: 34 SPSAELQCCAGWRQKDQECTIPI------CEGPDACQKDEVCVK-PGLCRCKPGFFGAHC 86
Query: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERC 542
S RCP WG C +C C G C G C C G +CE PC G +G RC
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHG-----RC 141
Query: 543 DCSHADGCHPTTGHCRCLPGW-------------SGVHCDS-----VCAEGRWGPNCSLP 584
D P TG C C PGW + C+ VC G WG CS
Sbjct: 142 D--------PATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFR 193
Query: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
C C +G+ C D G C C PG+ G CQ+ C +CV G C +G
Sbjct: 194 CNC-HGSPCEQDSGRCACRPGWWGPECQQQC--------------ECVR--GRCSAASGE 236
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGIC-TCTNNGTCNPIDRSCQ-CYPGWIGSDCSQP 702
C C PGF GA C CP+G G CA C C +N C+P SC+ C PGW G+ C QP
Sbjct: 237 CTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQP 296
Query: 703 CPPAHWGPNCIHTC-NCHNGAFCSAYDGECKCTPGW--TGLYCTQRCP--LGFYGKDCAL 757
C P +G +C C +C +G C G C+ G T L P L F G C
Sbjct: 297 CLPGTFGESCEQQCPHCRHGEACEPDTGHCQRCSGSRDTALIAGSLVPLLLLFLGLACCA 356
Query: 758 IC 759
C
Sbjct: 357 CC 358
Score = 205 bits (521), Expect = 2e-52
Identities = 104/288 (36%), Positives = 134/288 (46%), Gaps = 42/288 (14%)
Query: 93 QCCPGFYESGEMC-VPHCA--DKCVHGR-CIAPNTCQCEPGWGGTNCSSACDGDHWGPHC 148
QCC G+ + + C +P C D C C+ P C+C+PG+ G +CSS C G +WGP C
Sbjct: 40 QCCAGWRQKDQECTIPICEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDC 99
Query: 149 TSRCQCKNGALCNPITGACHCAAGFRGWRCE-----------------DRCEQGTYGNDC 191
C C C P TGAC C A G RCE CE G + + C
Sbjct: 100 RESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTC 159
Query: 192 HQRCQCQNGAT-CDHVTGECRCPPGYTGAFC----------------EDLCPPGKHGPQC 234
+ CQC A C+ TG C C PG+ G C C PG GP+C
Sbjct: 160 RRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPEC 219
Query: 235 EQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQEC-QCHNGGTCDAAT 293
+Q+C C G C +GEC+CP G+ G C PCP G G C+ C +C + C T
Sbjct: 220 QQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDT 278
Query: 294 GQCH-CSPGYTGERCQDECPVGTYGVLCAETC-QCVNGGKCYHVSGAC 339
G C C PG+ G +CQ C GT+G C + C C +G C +G C
Sbjct: 279 GSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
Score = 197 bits (501), Expect = 5e-50
Identities = 94/264 (35%), Positives = 121/264 (45%), Gaps = 38/264 (14%)
Query: 383 GECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTP 442
G C CKPG+ G +C+ C ++G C++ C C C+ TG C C G C P
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 443 CPLGTYG-----------------INCSSRCGCKNDAV-CSPVDGSCTCKAGWHGVDCSI 484
C G +G C C C A C G+C CK GW G CS
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 485 R----------------CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP 528
R C G WG C C+C+ G C+ G CTC PG+RG +CELP
Sbjct: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVR-GRCSAASGECTCPPGFRGARCELP 251
Query: 529 CQDGTYGLNCAERCD-CSHADGCHPTTGHCR-CLPGWSGVHCDSVCAEGRWGPNCSLPC- 585
C G++G+ CA C C H + C P TG C C PGW+G C C G +G +C C
Sbjct: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCP 311
Query: 586 YCKNGASCSPDDGICECAPGFRGT 609
+C++G +C PD G C+ G R T
Sbjct: 312 HCRHGEACEPDTGHCQRCSGSRDT 335
Score = 192 bits (488), Expect = 2e-48
Identities = 105/309 (33%), Positives = 136/309 (44%), Gaps = 48/309 (15%)
Query: 250 TGECSCPSGWM--GTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC 307
+ E C +GW C P EG C C G C C PG+ G C
Sbjct: 36 SAELQCCAGWRQKDQECTIPICEGPDA--------CQKDEVC-VKPGLCRCKPGFFGAHC 86
Query: 308 QDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARL------------- 354
CP +G C E+C C G+C +GAC C+A G RCE
Sbjct: 87 SSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATG 146
Query: 355 ---CPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCS---------- 401
C G + C + C C+ C +G C CKPGW G C+ C+
Sbjct: 147 VCHCEPGWWSSTCRRPCQCNTAAAR-CEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDS 205
Query: 402 ------PGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSR 455
PG++G CQQ C C G C + +G+CTC PGF+G C PCP G++G+ C+
Sbjct: 206 GRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHS 264
Query: 456 CG-CKNDAVCSPVDGSC-TCKAGWHGVDCSIRCPSGTWGFGCNLTC-QCLNGGACNTLDG 512
CG CK++ CSP GSC +C+ GW+G C C GT+G C C C +G AC G
Sbjct: 265 CGRCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTG 324
Query: 513 TCTCAPGWR 521
C G R
Sbjct: 325 HCQRCSGSR 333
Score = 165 bits (417), Expect = 3e-40
Identities = 93/279 (33%), Positives = 118/279 (42%), Gaps = 46/279 (16%)
Query: 581 CSLPCYCKNGASCSPDD-----GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS 635
C++P C+ +C D+ G+C C PGF G C C ++G C ++CP H
Sbjct: 52 CTIPI-CEGPDACQKDEVCVKPGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCP--CHPH 108
Query: 636 GPCHHITGLCDCLPGFTGALCNEVCPSGRFGK--NCAGICTC----------------TN 677
G C TG C C GA C C G G+ G+C C T
Sbjct: 109 GQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTA 168
Query: 678 NGTCNPIDRSCQCYPGWIGSDCS-------QPCP---------PAHWGPNCIHTCNCHNG 721
C +C C PGW G CS PC P WGP C C C G
Sbjct: 169 AARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRG 228
Query: 722 AFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALIC-QCQNGADCDHISGQC-TCRTG 779
CSA GEC C PG+ G C CP G +G CA C +C++ C +G C +C G
Sbjct: 229 R-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPG 287
Query: 780 FMGRHCEQKCPSGTYGYGCRQIC-DCLNNSTCDHITGTC 817
+ G C+Q C GT+G C Q C C + C+ TG C
Sbjct: 288 WNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
Score = 156 bits (395), Expect = 9e-38
Identities = 79/224 (35%), Positives = 98/224 (43%), Gaps = 37/224 (16%)
Query: 643 GLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
GLC C PGF GA C+ CP +G +C C C +G C P +CQC G+ C P
Sbjct: 73 GLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFP 132
Query: 703 -----------------CPPAHWGPNCIHTCNCHNGAF-CSAYDGECKCTPGWTGLYCTQ 744
C P W C C C+ A C G C C PGW G C+
Sbjct: 133 CACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSF 192
Query: 745 RCPL----------------GFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQK 788
RC G++G +C C+C G C SG+CTC GF G CE
Sbjct: 193 RCNCHGSPCEQDSGRCACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELP 251
Query: 789 CPSGTYGYGCRQICD-CLNNSTCDHITGTC-YCSPGWKGARCDQ 830
CP+G++G C C C +N C TG+C C PGW G +C Q
Sbjct: 252 CPAGSHGVQCAHSCGRCKHNEPCSPDTGSCESCEPGWNGTQCQQ 295
Score = 129 bits (325), Expect = 1e-29
Identities = 70/185 (37%), Positives = 88/185 (47%), Gaps = 23/185 (12%)
Query: 94 CCPGFYESGEMCVPHCADKCVHGRCI-APNTCQCEPGWGGTNCS-------SACDGDH-- 143
C PG++ S C C RC A C C+PGW G CS S C+ D
Sbjct: 150 CEPGWWSS--TCRRPCQCNTAAARCEQATGACVCKPGWWGRRCSFRCNCHGSPCEQDSGR 207
Query: 144 -------WGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRC- 195
WGP C +C+C G C+ +G C C GFRG RCE C G++G C C
Sbjct: 208 CACRPGWWGPECQQQCECVRGR-CSAASGECTCPPGFRGARCELPCPAGSHGVQCAHSCG 266
Query: 196 QCQNGATCDHVTGECR-CPPGYTGAFCEDLCPPGKHGPQCEQRCP-CQNGGVCHHVTGEC 253
+C++ C TG C C PG+ G C+ C PG G CEQ+CP C++G C TG C
Sbjct: 267 RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHGEACEPDTGHC 326
Query: 254 SCPSG 258
SG
Sbjct: 327 QRCSG 331
Score = 113 bits (283), Expect = 9e-25
Identities = 59/195 (30%), Positives = 82/195 (42%), Gaps = 36/195 (18%)
Query: 669 CAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYD 728
C G C + C C+C PG+ G+ CS CP +WGP+C +C CH C
Sbjct: 57 CEGPDACQKDEVCVK-PGLCRCKPGFFGAHCSSRCPGQYWGPDCRESCPCHPHGQCEPAT 115
Query: 729 GECKCTPGWTGLYCTQRCPLGFYGK-----------------DCALICQCQN-GADCDHI 770
G C+C G C C G +G+ C CQC A C+
Sbjct: 116 GACQCQADRWGARCEFPCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQA 175
Query: 771 SGQCTCRTGFMGRHCEQK----------------CPSGTYGYGCRQICDCLNNSTCDHIT 814
+G C C+ G+ GR C + C G +G C+Q C+C+ C +
Sbjct: 176 TGACVCKPGWWGRRCSFRCNCHGSPCEQDSGRCACRPGWWGPECQQQCECV-RGRCSAAS 234
Query: 815 GTCYCSPGWKGARCD 829
G C C PG++GARC+
Sbjct: 235 GECTCPPGFRGARCE 249
Score = 94.7 bits (234), Expect = 4e-19
Identities = 52/159 (32%), Positives = 66/159 (41%), Gaps = 27/159 (16%)
Query: 689 QCYPGWIGSDCSQPCP-PAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCP 747
QC GW D Q C P GP+ C C G C+C PG+ G +C+ RCP
Sbjct: 40 QCCAGWRQKD--QECTIPICEGPDA-----CQKDEVC-VKPGLCRCKPGFFGAHCSSRCP 91
Query: 748 LGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG------------ 795
++G DC C C C+ +G C C+ G CE C G +G
Sbjct: 92 GQYWGPDCRESCPCHPHGQCEPATGACQCQADRWGARCEFPCACGPHGRCDPATGVCHCE 151
Query: 796 -----YGCRQICDCLNNST-CDHITGTCYCSPGWKGARC 828
CR+ C C + C+ TG C C PGW G RC
Sbjct: 152 PGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGRRC 190
Score = 59.3 bits (142), Expect = 2e-08
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 5/77 (6%)
Query: 102 GEMCVPHCADKCVHGRCIAPNT--CQ-CEPGWGGTNCSSACDGDHWGPHCTSRC-QCKNG 157
G C C +C H +P+T C+ CEPGW GT C C +G C +C C++G
Sbjct: 258 GVQCAHSCG-RCKHNEPCSPDTGSCESCEPGWNGTQCQQPCLPGTFGESCEQQCPHCRHG 316
Query: 158 ALCNPITGACHCAAGFR 174
C P TG C +G R
Sbjct: 317 EACEPDTGHCQRCSGSR 333
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 182 bits (463), Expect = 1e-45
Identities = 152/495 (30%), Positives = 203/495 (41%), Gaps = 98/495 (19%)
Query: 120 APNTCQCEPGWGGTNCSSA------CDGDHWGPHCTSRCQCKNGA-LCNPITGACHCAAG 172
A CQC PG+ G++C S +G +G C CQC A C+ +TG C
Sbjct: 720 AVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKD 778
Query: 173 FRGWRCEDRCEQGTYG-------NDCHQRCQCQNGATCDHVTGECR-----------CPP 214
G D+C G YG DC Q C C ++ + C CP
Sbjct: 779 HTGGPYCDKCLPGFYGEPTKGTSEDC-QPCACPLNIPSNNFSPTCHLDRSLGLICDGCPV 837
Query: 215 GYTGAFCEDLC-----PPGKHGPQCEQRCPCQNG------GVCHHVTGEC-SCPSGWMGT 262
GYTG CE P G C Q C C + G C ++G C C G G
Sbjct: 838 GYTGPRCERCAEGYFGQPSVPGGSC-QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 263 VCGQPCPEGRFG-----KNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPV 313
C + C +G FG KNC Q C+C+ GG+ C + TGQC C G+RC D+C
Sbjct: 897 YC-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKA 953
Query: 314 GTYGVLCAETCQCVN----GGKCY--HVSGACLCEAGFAGERCEARLCPEGLYGIK---C 364
GT+G+ A C N G K + SG C C+ G G++C+ C G + + C
Sbjct: 954 GTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR--CAHGYFNFQEGGC 1011
Query: 365 DKRCPC-HLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ---QICSCQN--- 417
C C HL N +C P +G C C P G C++ C+P +G + + C+C
Sbjct: 1012 -TACECSHLGN--NCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGS 1067
Query: 418 -GADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGC---KNDAV---------- 463
C+ TG+C C P F G C T C G + + C C DA
Sbjct: 1068 LDFQCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCS 1126
Query: 464 CSPVDGSCTCKAGWHGVDCSIRCPSGTWG------FGCNLTCQCLNGGA-CNTLDGTCTC 516
CS G CTCK G+ C RC G +G GC+ +C C C+ G
Sbjct: 1127 CSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCS-SCYCFGTTTQCSEAKGLIRT 1184
Query: 517 APGWRGEKCELPCQD 531
+ E+ LP D
Sbjct: 1185 WVTLKAEQTILPLVD 1199
Score = 181 bits (460), Expect = 3e-45
Identities = 148/498 (29%), Positives = 205/498 (41%), Gaps = 105/498 (21%)
Query: 167 CHCAAGFRGWRCED-----RCEQGTYGNDCHQRCQCQNGA-TCDHVTGEC-RCPPGYTGA 219
C C G+ G CE R GT + CQC A +CD VTGEC C G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 220 FCEDLCPPGKHGPQCE------QRCPCQNGGVCHHVTGEC-----------SCPSGWMGT 262
+C D C PG +G + Q C C ++ + C CP G+ G
Sbjct: 784 YC-DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 263 VCGQPCPEGRFGK-----NCSQECQCHNG------GTCDAATGQC-HCSPGYTGERCQDE 310
C + C EG FG+ Q CQC++ G+CD+ +G C C PG TG C +
Sbjct: 843 RC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC-EL 900
Query: 311 CPVGTYG----VLCAETCQCVNGGK----CYHVSGACLCEAGFAGERCEARLCPEGLYGI 362
C G +G + C+C GG C+ +G C C A G+RC+ C G +G+
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK--CKAGTFGL 958
Query: 363 KCDKRC-PCHLEN----THSCHPMSGECACKPGWSGLYCNETCSPGFYG--EACQQICSC 415
+ + C PC+ + + C SG+C C+PG +G C + C+ G++ E C C
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKC-DRCAHGYFNFQEGGCTACEC 1016
Query: 416 QN-GADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN-------DAVCSPV 467
+ G +CD TG+C C P G CS C T+G + ++ C N D C+
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVN 1075
Query: 468 DGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCEL 527
G C C + G C+ C G W N CN D C L
Sbjct: 1076 TGQCNCHPKFSGAKCT-ECSRGHW-----------NYPRCNLCD-------------CFL 1110
Query: 528 PCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLP--- 584
P D T + ++C CS TG C C G+HCD C G++G + P
Sbjct: 1111 PGTDATTCDSETKKCSCS------DQTGQCTCKVNVEGIHCDR-CRPGKFGLDAKNPLGC 1163
Query: 585 --CYC-KNGASCSPDDGI 599
CYC CS G+
Sbjct: 1164 SSCYCFGTTTQCSEAKGL 1181
Score = 167 bits (424), Expect = 4e-41
Identities = 151/502 (30%), Positives = 197/502 (39%), Gaps = 115/502 (22%)
Query: 385 CACKPGWSGLYCNETCSPG-------FYGEACQQICSCQNGAD-CDSVTGKCT------- 429
C C PG++G C E+C P +G C+ C C A+ CD VTG+C
Sbjct: 724 CQCPPGYTGSSC-ESCWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGECLNCKDHTG 781
Query: 430 ------CAPGFKGI-------DCST-PCPLGTYGINCSSRCGCKNDA--VCSPVDGSCTC 473
C PGF G DC CPL N S C +C DG C
Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC---DG---C 835
Query: 474 KAGWHGVDCSIRCPSGTWGF-----GCNLTCQCLNG------GACNTLDGTCT-CAPGWR 521
G+ G C RC G +G G CQC + G+C++L G+C C PG
Sbjct: 836 PVGYTGPRCE-RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 522 GEKCELPCQDGTYG-----LNCAERCDC----SHADGCHPTTGHCRCLPGWSGVHCDSVC 572
G CEL C DG +G NC + C C S ++ CH TG C C G CD C
Sbjct: 895 GRYCEL-CADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK-C 951
Query: 573 AEGRWGPNCS---LPCYCKNGASCSPD---DGICECAPGFRGTTCQRICSPGFYG-HRCS 625
G +G + +PC C + S S D G C C PG G C R C+ G++
Sbjct: 952 KAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR-CAHGYFNFQEGG 1010
Query: 626 QTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPS--GRFGKNCAGICTCTNNGT--- 680
T +C H C TG C C P G C++ P+ G C C+ G+
Sbjct: 1011 CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDF 1070
Query: 681 -CNPIDRSCQCYPGWIGSDCSQPCPPAHWG-PNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
CN C C+P + G+ C++ C HW P C + C+C PG
Sbjct: 1071 QCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRC-NLCDCF--------------LPGTD 1114
Query: 739 GLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGC 798
C K C+ C Q G QCTC+ G HC+ +C G +G
Sbjct: 1115 ATTCDSET------KKCS--CSDQTG--------QCTCKVNVEGIHCD-RCRPGKFGLDA 1157
Query: 799 RQICDCLNNSTCDHITGTCYCS 820
+ C S+C T CS
Sbjct: 1158 KNPLGC---SSCYCFGTTTQCS 1176
Score = 166 bits (420), Expect = 1e-40
Identities = 153/484 (31%), Positives = 201/484 (41%), Gaps = 106/484 (21%)
Query: 287 GTCDAATGQCHCSPGYTGERCQDECP-----VGT-YGVLCAETCQCV-NGGKCYHVSGAC 339
G+ AA C C PGYTG C+ P GT +G +C E CQC + C V+G C
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGEC 773
Query: 340 L-CEAGFAGERCEARLCPEGLYG-------IKCDK-RCPCHLENTH---SCH---PMSGE 384
L C+ G C+ C G YG C CP ++ + + +CH +
Sbjct: 774 LNCKDHTGGPYCDK--CLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLI 831
Query: 385 C-ACKPGWSGLYCNETCSPGFYGE------ACQQICSCQNGAD------CDSVTGKC-TC 430
C C G++G C E C+ G++G+ +CQ C C + D CDS++G C C
Sbjct: 832 CDGCPVGYTGPRC-ERCAEGYFGQPSVPGGSCQP-CQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 431 APGFKGIDCSTPCPLGTYG-----INCS-SRC--GCKNDAVCSPVDGSCTCKAGWHGVDC 482
PG G C C G +G NC RC G VC G C C+A G C
Sbjct: 890 KPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 483 SIRCPSGTWGF----GCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTY 534
+C +GT+G GC + C C + G+ C G C C PG G+KC+ C G +
Sbjct: 949 D-KCKAGTFGLQSARGC-VPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCD-RCAHGYF 1004
Query: 535 GL--NCAERCDCSH-ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGA 591
C+CSH + C P TG C C P G C S CA WG + + C N +
Sbjct: 1005 NFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCS 1063
Query: 592 S-------CSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
+ C+ + G C C P F G C CS G + + P+C L
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNY------PRC-----------NL 1105
Query: 645 CDC-LPGFTGALCNEVCPSGRFGKNCA-----GICTCTNNGTCNPIDRSCQCYPGWIGSD 698
CDC LPG C+ K C+ G CTC N DR C PG G D
Sbjct: 1106 CDCFLPGTDATTCDSET------KKCSCSDQTGQCTCKVNVEGIHCDR---CRPGKFGLD 1156
Query: 699 CSQP 702
P
Sbjct: 1157 AKNP 1160
Score = 139 bits (350), Expect = 2e-32
Identities = 115/379 (30%), Positives = 156/379 (41%), Gaps = 72/379 (18%)
Query: 514 CTCAPGWRGEKCELPCQ------DGTYGLNCAERCDC-SHADGCHPTTGHC-RCLPGWSG 565
C C PG+ G CE C +GT E C C HA+ C TG C C G
Sbjct: 724 CQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 566 VHCDSVCAEGRWGP-------NCSLPCYC-------KNGASCSPDDG---ICE-CAPGFR 607
+CD C G +G +C PC C +C D IC+ C G+
Sbjct: 783 PYCDK-CLPGFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 608 GTTCQRICSPGFYGHRC--SQTCPQCVHSSGPCHHITGLCD--------CLPGFTGALCN 657
G C+R C+ G++G +C C + I G CD C PG TG C
Sbjct: 841 GPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC- 898
Query: 658 EVCPSGRFG-----KNCAGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHW 708
E+C G FG KNC C C G+ C+ C+C G C + C +
Sbjct: 899 ELCADGYFGDAVDAKNCQP-CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK-CKAGTF 956
Query: 709 G----PNCIHTCNCHN---GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG--KDCALIC 759
G C+ CNC++ +F G+C C PG TG C RC G++ + C
Sbjct: 957 GLQSARGCV-PCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGCTAC 1014
Query: 760 QCQN-GADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNST-------CD 811
+C + G +CD +G+C C +G C KC T+G+ C N ST C+
Sbjct: 1015 ECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 812 HITGTCYCSPGWKGARCDQ 830
TG C C P + GA+C +
Sbjct: 1074 VNTGQCNCHPKFSGAKCTE 1092
Score = 135 bits (340), Expect = 2e-31
Identities = 136/520 (26%), Positives = 182/520 (35%), Gaps = 151/520 (29%)
Query: 42 VTVQESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYES 101
V +Q +Y D I+ S ++ VSY T G QC PG+ S
Sbjct: 684 VLLQITYSFGMDAIFRLSSVNL-------ESAVSYPT---DGSIAAAVEVCQCPPGYTGS 733
Query: 102 -----------------GEMCVP-HC---ADKC--VHGRCIAPNTCQCEPGWGGTNCSSA 138
G +C P C A+ C V G C+ C+ GG C
Sbjct: 734 SCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL-----NCKDHTGGPYCDKC 788
Query: 139 CDGDHWGP-----HCTSRCQCKNGALCNPITGACH-----------CAAGFRGWRCEDRC 182
G + P C C N + CH C G+ G RCE RC
Sbjct: 789 LPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCE-RC 847
Query: 183 EQGTYGN------DCHQRCQCQNG------ATCDHVTGECR-CPPGYTGAFCEDLCPPGK 229
+G +G C Q CQC + +CD ++G C C PG TG +CE LC G
Sbjct: 848 AEGYFGQPSVPGGSC-QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCE-LCADGY 905
Query: 230 HGPQCE----QRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQP-------------- 267
G + Q C C GG VCH TG+C C + G C +
Sbjct: 906 FGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCV 965
Query: 268 ---------------------CPEGRFGKNCSQ--------------ECQC-HNGGTCDA 291
C G GK C + C+C H G CD
Sbjct: 966 PCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 292 ATGQCHCSPGYTGERCQDECPVGTYG---VLCAETCQCVNGG----KCYHVSGACLCEAG 344
TG+C C P GE+C +C T+G + C C G +C +G C C
Sbjct: 1026 KTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPK 1084
Query: 345 FAGERCEARLCPEGLYGIKCDKRCPCHLENTH-----------SCHPMSGECACKPGWSG 393
F+G +C C G + C C L T SC +G+C CK G
Sbjct: 1085 FSGAKCTE--CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEG 1142
Query: 394 LYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPG 433
++C + C PG +G + C + C T +C+ A G
Sbjct: 1143 IHC-DRCRPGKFGLDAKNPLGC-SSCYCFGTTTQCSEAKG 1180
Score = 128 bits (321), Expect = 4e-29
Identities = 127/469 (27%), Positives = 175/469 (37%), Gaps = 97/469 (20%)
Query: 447 TYGINCSSRCGCKN--DAVCSPVDGS-------CTCKAGWHGVDCSIRCP-----SGTWG 492
++G++ R N AV P DGS C C G+ G C P +GT
Sbjct: 691 SFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIF 750
Query: 493 FGCNLTCQCL-NGGACNTLDGTC-TCAPGWRGEKCELPCQDGTYG------LNCAERCDC 544
G CQC + +C+ + G C C G C+ C G YG + C C
Sbjct: 751 GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCAC 809
Query: 545 S---HADGCHPTTGHCR--------CLPGWSGVHCDSVCAEGRWGP------NCSLPCYC 587
++ PT R C G++G C+ CAEG +G +C PC C
Sbjct: 810 PLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQ-PCQC 867
Query: 588 KNG------ASCSPDDGICE-CAPGFRGTTCQRICSPGFYGHRC-SQTCPQCVHSSGP-- 637
+ SC G C C PG G C+ +C+ G++G ++ C C ++G
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQPCRCNAGGSF 926
Query: 638 ---CHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS------- 687
CH TG C+C G C++ C +G FG A C N CN
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCN---CNSFGSKSFDCEES 982
Query: 688 --CQCYPGWIGSDCSQPCPPAHWG---PNCIHTCNC-HNGAFCSAYDGECKCTPGWTGLY 741
C C PG G C + C ++ C C C H G C G C C P G
Sbjct: 983 GQCWCQPGVTGKKCDR-CAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGEK 1040
Query: 742 CTQRCPLGFYGKDCALICQCQNGA-------DCDHISGQCTCRTGFMGRHCEQKCPSGTY 794
C+ +C +G C+ N + C+ +GQC C F G C + C G +
Sbjct: 1041 CS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHW 1098
Query: 795 GYGCRQICDCLNNST-------------CDHITGTCYCSPGWKGARCDQ 830
Y +CDC T C TG C C +G CD+
Sbjct: 1099 NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 74.7 bits (182), Expect = 5e-13
Identities = 70/242 (28%), Positives = 92/242 (38%), Gaps = 74/242 (30%)
Query: 209 ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPC 268
+C CP GY+G CE C PG + R Q GG P +GT
Sbjct: 1379 KCDCPLGYSGLSCE-ACLPGFY------RLRSQPGG---------RTPGPTLGTCV---- 1418
Query: 269 PEGRFGKNCSQECQCH-NGGTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCA----- 321
CQC+ + CD T C +C G+ C+ C +G YG++
Sbjct: 1419 -----------PCQCNGHSSLCDPETSICQNCQHHTAGDFCE-RCALGYYGIVKGLPNDC 1466
Query: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPM 381
+ C C + S +C+ E G RC A CP G G C++
Sbjct: 1467 QQCACPLISSSNNFSPSCVAE-GLDDYRCTA--CPRGYEGQYCER--------------- 1508
Query: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD----CDSVTGKCTCAPGFKGI 437
C PG++G SPG G +CQ+ C C CD VTG CTC PG G
Sbjct: 1509 -----CAPGYTG-------SPGNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 438 DC 439
C
Sbjct: 1556 KC 1557
Score = 71.2 bits (173), Expect = 5e-12
Identities = 68/230 (29%), Positives = 91/230 (39%), Gaps = 60/230 (26%)
Query: 124 CQCEPGWGGTNCSSACDGDHW----------GPHCTS--RCQCK-NGALCNPITGAC-HC 169
C C G+ G +C + G + GP + CQC + +LC+P T C +C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 170 AAGFRGWRCEDRCEQGTYG------NDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCED 223
G CE RC G YG NDC Q+C C ++ ++ + C G C
Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC-QQCACPLISSSNNFSPSC-VAEGLDDYRCT- 1495
Query: 224 LCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQC 283
CP G G CE+ C G+ G+ G G +C QEC+C
Sbjct: 1496 ACPRGYEGQYCER------------------CAPGYTGS-------PGNPGGSC-QECEC 1529
Query: 284 HNGGT----CDAATGQCHCSPGYTGERCQDECP-----VGTYGVLCAETC 324
G+ CD TG C C PG TG +C D C G V C + C
Sbjct: 1530 DPYGSLPVPCDPVTGFCTCRPGATGRKC-DGCKHWHAREGWECVFCGDEC 1578
Score = 65.1 bits (157), Expect = 4e-10
Identities = 63/228 (27%), Positives = 74/228 (32%), Gaps = 67/228 (29%)
Query: 384 ECACKPGWSGLYCNETCSPGFYGEACQQ-------------ICSCQNGAD-CDSVTGKCT 429
+C C G+SGL C E C PGFY Q C C + CD T C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 430 CAPGFKGIDCSTPCPLGTYGI-----NCSSRCGCKNDAVCSPVDGSCT-----------C 473
D C LG YGI N +C C + + SC C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 474 KAGWHGVDCSIRCPSGTWGF-----GCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEK 524
G+ G C RC G G G C+C G+ C+ + G CTC PG G K
Sbjct: 1498 PRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 525 CELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVC 572
C DGC H GW V C C
Sbjct: 1557 C----------------------DGCK----HWHAREGWECVFCGDEC 1578
Score = 64.3 bits (155), Expect = 6e-10
Identities = 61/213 (28%), Positives = 80/213 (37%), Gaps = 62/213 (29%)
Query: 645 CDCLPGFTGALCNEVCPSG--RFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
CDC G++G C E C G R G GTC P CQC + S
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVP----CQC------NGHSSL 1428
Query: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG------KDCA 756
C P T C N C G +C +RC LG+YG DC
Sbjct: 1429 CDP--------ETSICQN------------CQHHTAGDFC-ERCALGYYGIVKGLPNDCQ 1467
Query: 757 LICQCQNGADCDHISGQCT-----------CRTGFMGRHCEQKCPS-----GTYGYGCRQ 800
C C + ++ S C C G+ G++CE+ P G G C++
Sbjct: 1468 Q-CACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQE 1526
Query: 801 ICDCLNNST----CDHITGTCYCSPGWKGARCD 829
C+C + CD +TG C C PG G +CD
Sbjct: 1527 -CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 63/219 (28%)
Query: 671 GICTCTNNGTCNPIDRS-----CQCYPGWIGSDCSQPCPPAHWGP----------NCIHT 715
G+C C + P+D + C+C G C Q CP H P C
Sbjct: 285 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EA 343
Query: 716 CNCHNGAFCSAYD-------------------GEC-KCTPGWTGLYCTQRCPLGF----- 750
CNCH A YD G C CT G+ C + C GF
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC-ETCTDGFFRPKG 402
Query: 751 ----YGKDCALICQCQNGADCDHI-------------SGQCTCRTGFMGRHCEQKCPSGT 793
Y + C C C + + G C C+TGF G C+ +C G
Sbjct: 403 VSPNYPRPCQ-PCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD-RCARGY 460
Query: 794 YGYGCRQICDC--LNNSTCDHITGTCYCSPGWKGARCDQ 830
GY + C+C L + D G C C +G C +
Sbjct: 461 TGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/182 (30%), Positives = 73/182 (40%), Gaps = 41/182 (22%)
Query: 514 CTCAPGWRGEKCELPCQDGTYGLNCAER-------------CDCS-HADGCHPTTGHCR- 558
C C G+ G CE C G Y L C C+ H+ C P T C+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 559 CLPGWSGVHCDSVCAEGRWG-----PNCSLPCYC---KNGASCSP-------DDGICECA 603
C +G C+ CA G +G PN C C + + SP DD C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 604 P-GFRGTTCQRICSPGFYGHRCSQ--TCPQCVHSSG-----PCHHITGLCDCLPGFTGAL 655
P G+ G C+R C+PG+ G + +C +C PC +TG C C PG TG
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 656 CN 657
C+
Sbjct: 1557 CD 1558
Score = 53.9 bits (128), Expect = 8e-07
Identities = 69/270 (25%), Positives = 94/270 (34%), Gaps = 53/270 (19%)
Query: 332 CYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP----------CHLENTH----S 377
CY + AC + RCE C G CD+ CP L T +
Sbjct: 289 CYGHARACPLDPATNKSRCE---CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN--GADCDSVTGKCTCAPGF- 434
CH + EC + + + G C+ QN G +C+ TC GF
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCT-QNTAGINCE------TCTDGFF 398
Query: 435 --KGIDCS-----TPC---PLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSI 484
KG+ + PC P+G+ C + A GSC CK G+ GV C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKD---EKHARRGLAPGSCHCKTGFGGVSCD- 454
Query: 485 RCPSGTWGFGCNLTCQCLNGGACN--TLDGTCTCAPGWRGEKCELPCQDGTYGL-----N 537
RC G G+ C C G+ N G C C G C C+ G + L
Sbjct: 455 RCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFNLQEDNWK 513
Query: 538 CAERCDCS----HADGCHPTTGHCRCLPGW 563
+ C CS + T G + + GW
Sbjct: 514 GCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 51.2 bits (121), Expect = 5e-06
Identities = 73/301 (24%), Positives = 100/301 (33%), Gaps = 60/301 (19%)
Query: 450 INCSSRCGCKNDAVCSPVDGS-----CTCKAGWHGVDCSIRCPS---GTWGFGCNLT-CQ 500
I+ C C A P+D + C C+ G C CP W G LT +
Sbjct: 281 ISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTE 340
Query: 501 CLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHC-RC 559
C ACN C ++ Y N A R + G + G C C
Sbjct: 341 C---EACN----------------CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381
Query: 560 LPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGF 619
+G++C++ C +G + P P Y + C P C C P G
Sbjct: 382 TQNTAGINCET-CTDGFFRPKGVSPNYPR---PCQP----CHCDP------------IGS 421
Query: 620 YGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNG 679
C + P G C C GF G C+ C G G C C+ G
Sbjct: 422 LNEVCVKDEKHARRGLAP-----GSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLG 475
Query: 680 TCN--PIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGW 737
+ N P C C G DCS+ C + + C + FCS C+ + W
Sbjct: 476 SKNEDPCFGPCICKENVEGGDCSR-CKSGFFNLQEDNWKGC-DECFCSGVSNRCQ-SSYW 532
Query: 738 T 738
T
Sbjct: 533 T 533
Score = 48.9 bits (115), Expect = 3e-05
Identities = 65/232 (28%), Positives = 78/232 (33%), Gaps = 57/232 (24%)
Query: 413 CSCQN---GADCDSVTGKCTCAPGFKGIDCSTPCPLGTY-------GINCSSRCG-CKND 461
C C++ G CD C PGF P GT+ NC + C D
Sbjct: 307 CECEHNTCGDSCDQ------CCPGFH----QKPWRAGTFLTKTECEACNCHGKAEECYYD 356
Query: 462 AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWR 521
+ + S + + G I C T G C TC G+
Sbjct: 357 ENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE------------------TCTDGFF 398
Query: 522 GEK-----CELPCQ----DGTYGLNCAERCDCSHAD-GCHPTTGHCRCLPGWSGVHCDSV 571
K PCQ D LN D HA G P G C C G+ GV CD
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAP--GSCHCKTGFGGVSCDR- 455
Query: 572 CAEGRWG-PNCSLPCYCKNGASCSPDD--GICECAPGFRGTTCQRICSPGFY 620
CA G G P+C C C S + D G C C G C R C GF+
Sbjct: 456 CARGYTGYPDCK-ACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF 505
Score = 47.8 bits (112), Expect = 6e-05
Identities = 47/182 (25%), Positives = 59/182 (32%), Gaps = 57/182 (31%)
Query: 93 QCCPGFYESG------------EMCVPH-CADKC--------------VHGRCIAPNTC- 124
QCCPGF++ E C H A++C + G+ I C
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379
Query: 125 QCEPGWGGTNCSSACDG----DHWGPHCTSRCQCKNGALCNPI----------------- 163
C G NC + DG P+ CQ C+PI
Sbjct: 380 NCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQ---PCHCDPIGSLNEVCVKDEKHARRG 436
Query: 164 --TGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ--NGATCDHVTGECRCPPGYTGA 219
G+CHC GF G C DRC +G G + C C D G C C G
Sbjct: 437 LAPGSCHCKTGFGGVSC-DRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGG 495
Query: 220 FC 221
C
Sbjct: 496 DC 497
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 17/120 (14%)
Query: 95 CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQC 154
C E+CV D+ R +AP +C C+ G+GG +C G P C + C C
Sbjct: 416 CDPIGSLNEVCVK---DEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKA-CNC 471
Query: 155 KNGALCN--PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRC 212
N P G C C G C RC+ G + Q N CD EC C
Sbjct: 472 SGLGSKNEDPCFGPCICKENVEGGDC-SRCKSGFF------NLQEDNWKGCD----ECFC 520
Score = 42.0 bits (97), Expect = 0.003
Identities = 69/272 (25%), Positives = 83/272 (30%), Gaps = 76/272 (27%)
Query: 102 GEMCVPHC-ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP----------HCTS 150
G MC+ + A C + C+CE G +C C G H P C +
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 151 RCQCKNGA-------------LCNPITG-------ACHCAAGFRGWRCEDRCEQG----- 185
C C A L I G +C G CE C G
Sbjct: 344 -CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPK 401
Query: 186 ----TYGNDCHQRCQCQNGATCDHV-------------TGECRCPPGYTGAFCEDLCPPG 228
Y C Q C C + + V G C C G+ G C D C G
Sbjct: 402 GVSPNYPRPC-QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC-DRCARG 459
Query: 229 KHG-PQCEQRCPCQNGGVCHH--VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285
G P C + C C G + G C C G C + C G F Q N
Sbjct: 460 YTGYPDC-KACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF------NLQEDN 511
Query: 286 GGTCDAATGQCHCSPGYTGERCQDECPVGTYG 317
CD +C CS RCQ TYG
Sbjct: 512 WKGCD----ECFCSG--VSNRCQSS--YWTYG 535
Score = 36.2 bits (82), Expect = 0.18
Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 35/157 (22%)
Query: 730 ECKCTPGWTGLYCTQRCPLGFY-------GK------DCALICQCQNGAD-CDHISGQC- 774
+C C G++GL C + C GFY G+ + CQC + CD + C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 775 TCRTGFMGRHCEQKCPSGTYGY------GCRQICDCLNNSTCDHITGTCY---------- 818
C+ G CE +C G YG C+Q C C S+ ++ + +C
Sbjct: 1438 NCQHHTAGDFCE-RCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 819 -CSPGWKGARCDQAGVIIVGNLNSLSRTSTALPADSY 854
C G++G C++ G+ + + D Y
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY 1532
Score = 35.0 bits (79), Expect = 0.41
Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 14/96 (14%)
Query: 93 QCCPGFYESGEMCVPHC-ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPH---- 147
QC S P C A+ RC A C G+ G C G P
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLDDYRCTA-----CPRGYEGQYCERCAPGYTGSPGNPGG 1522
Query: 148 CTSRCQCKN-GAL---CNPITGACHCAAGFRGWRCE 179
C+C G+L C+P+TG C C G G +C+
Sbjct: 1523 SCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 182 bits (463), Expect = 1e-45
Identities = 152/495 (30%), Positives = 203/495 (41%), Gaps = 98/495 (19%)
Query: 120 APNTCQCEPGWGGTNCSSA------CDGDHWGPHCTSRCQCKNGA-LCNPITGACHCAAG 172
A CQC PG+ G++C S +G +G C CQC A C+ +TG C
Sbjct: 720 AVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGECLNCKD 778
Query: 173 FRGWRCEDRCEQGTYG-------NDCHQRCQCQNGATCDHVTGECR-----------CPP 214
G D+C G YG DC Q C C ++ + C CP
Sbjct: 779 HTGGPYCDKCLPGFYGEPTKGTSEDC-QPCACPLNIPSNNFSPTCHLDRSLGLICDGCPV 837
Query: 215 GYTGAFCEDLC-----PPGKHGPQCEQRCPCQNG------GVCHHVTGEC-SCPSGWMGT 262
GYTG CE P G C Q C C + G C ++G C C G G
Sbjct: 838 GYTGPRCERCAEGYFGQPSVPGGSC-QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGR 896
Query: 263 VCGQPCPEGRFG-----KNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPV 313
C + C +G FG KNC Q C+C+ GG+ C + TGQC C G+RC D+C
Sbjct: 897 YC-ELCADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC-DKCKA 953
Query: 314 GTYGVLCAETCQCVN----GGKCY--HVSGACLCEAGFAGERCEARLCPEGLYGIK---C 364
GT+G+ A C N G K + SG C C+ G G++C+ C G + + C
Sbjct: 954 GTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR--CAHGYFNFQEGGC 1011
Query: 365 DKRCPC-HLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ---QICSCQN--- 417
C C HL N +C P +G C C P G C++ C+P +G + + C+C
Sbjct: 1012 -TACECSHLGN--NCDPKTGRCICPPNTIGEKCSK-CAPNTWGHSITTGCKACNCSTVGS 1067
Query: 418 -GADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGC---KNDAV---------- 463
C+ TG+C C P F G C T C G + + C C DA
Sbjct: 1068 LDFQCNVNTGQCNCHPKFSGAKC-TECSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCS 1126
Query: 464 CSPVDGSCTCKAGWHGVDCSIRCPSGTWG------FGCNLTCQCLNGGA-CNTLDGTCTC 516
CS G CTCK G+ C RC G +G GC+ +C C C+ G
Sbjct: 1127 CSDQTGQCTCKVNVEGIHCD-RCRPGKFGLDAKNPLGCS-SCYCFGTTTQCSEAKGLIRT 1184
Query: 517 APGWRGEKCELPCQD 531
+ E+ LP D
Sbjct: 1185 WVTLKAEQTILPLVD 1199
Score = 181 bits (460), Expect = 3e-45
Identities = 148/498 (29%), Positives = 205/498 (41%), Gaps = 105/498 (21%)
Query: 167 CHCAAGFRGWRCED-----RCEQGTYGNDCHQRCQCQNGA-TCDHVTGEC-RCPPGYTGA 219
C C G+ G CE R GT + CQC A +CD VTGEC C G
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 220 FCEDLCPPGKHGPQCE------QRCPCQNGGVCHHVTGEC-----------SCPSGWMGT 262
+C D C PG +G + Q C C ++ + C CP G+ G
Sbjct: 784 YC-DKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 263 VCGQPCPEGRFGK-----NCSQECQCHNG------GTCDAATGQC-HCSPGYTGERCQDE 310
C + C EG FG+ Q CQC++ G+CD+ +G C C PG TG C +
Sbjct: 843 RC-ERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC-EL 900
Query: 311 CPVGTYG----VLCAETCQCVNGGK----CYHVSGACLCEAGFAGERCEARLCPEGLYGI 362
C G +G + C+C GG C+ +G C C A G+RC+ C G +G+
Sbjct: 901 CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK--CKAGTFGL 958
Query: 363 KCDKRC-PCHLEN----THSCHPMSGECACKPGWSGLYCNETCSPGFYG--EACQQICSC 415
+ + C PC+ + + C SG+C C+PG +G C + C+ G++ E C C
Sbjct: 959 QSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKC-DRCAHGYFNFQEGGCTACEC 1016
Query: 416 QN-GADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN-------DAVCSPV 467
+ G +CD TG+C C P G CS C T+G + ++ C N D C+
Sbjct: 1017 SHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVN 1075
Query: 468 DGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCEL 527
G C C + G C+ C G W N CN D C L
Sbjct: 1076 TGQCNCHPKFSGAKCT-ECSRGHW-----------NYPRCNLCD-------------CFL 1110
Query: 528 PCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLP--- 584
P D T + ++C CS TG C C G+HCD C G++G + P
Sbjct: 1111 PGTDATTCDSETKKCSCS------DQTGQCTCKVNVEGIHCDR-CRPGKFGLDAKNPLGC 1163
Query: 585 --CYC-KNGASCSPDDGI 599
CYC CS G+
Sbjct: 1164 SSCYCFGTTTQCSEAKGL 1181
Score = 167 bits (424), Expect = 4e-41
Identities = 151/502 (30%), Positives = 197/502 (39%), Gaps = 115/502 (22%)
Query: 385 CACKPGWSGLYCNETCSPG-------FYGEACQQICSCQNGAD-CDSVTGKCT------- 429
C C PG++G C E+C P +G C+ C C A+ CD VTG+C
Sbjct: 724 CQCPPGYTGSSC-ESCWPRHRRVNGTIFGGICEP-CQCFGHAESCDDVTGECLNCKDHTG 781
Query: 430 ------CAPGFKGI-------DCST-PCPLGTYGINCSSRCGCKNDA--VCSPVDGSCTC 473
C PGF G DC CPL N S C +C DG C
Sbjct: 782 GPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLIC---DG---C 835
Query: 474 KAGWHGVDCSIRCPSGTWGF-----GCNLTCQCLNG------GACNTLDGTCT-CAPGWR 521
G+ G C RC G +G G CQC + G+C++L G+C C PG
Sbjct: 836 PVGYTGPRCE-RCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 522 GEKCELPCQDGTYG-----LNCAERCDC----SHADGCHPTTGHCRCLPGWSGVHCDSVC 572
G CEL C DG +G NC + C C S ++ CH TG C C G CD C
Sbjct: 895 GRYCEL-CADGYFGDAVDAKNC-QPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK-C 951
Query: 573 AEGRWGPNCS---LPCYCKNGASCSPD---DGICECAPGFRGTTCQRICSPGFYG-HRCS 625
G +G + +PC C + S S D G C C PG G C R C+ G++
Sbjct: 952 KAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDR-CAHGYFNFQEGG 1010
Query: 626 QTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPS--GRFGKNCAGICTCTNNGT--- 680
T +C H C TG C C P G C++ P+ G C C+ G+
Sbjct: 1011 CTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTVGSLDF 1070
Query: 681 -CNPIDRSCQCYPGWIGSDCSQPCPPAHWG-PNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
CN C C+P + G+ C++ C HW P C + C+C PG
Sbjct: 1071 QCNVNTGQCNCHPKFSGAKCTE-CSRGHWNYPRC-NLCDCF--------------LPGTD 1114
Query: 739 GLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGC 798
C K C+ C Q G QCTC+ G HC+ +C G +G
Sbjct: 1115 ATTCDSET------KKCS--CSDQTG--------QCTCKVNVEGIHCD-RCRPGKFGLDA 1157
Query: 799 RQICDCLNNSTCDHITGTCYCS 820
+ C S+C T CS
Sbjct: 1158 KNPLGC---SSCYCFGTTTQCS 1176
Score = 166 bits (420), Expect = 1e-40
Identities = 153/484 (31%), Positives = 201/484 (41%), Gaps = 106/484 (21%)
Query: 287 GTCDAATGQCHCSPGYTGERCQDECP-----VGT-YGVLCAETCQCV-NGGKCYHVSGAC 339
G+ AA C C PGYTG C+ P GT +G +C E CQC + C V+G C
Sbjct: 715 GSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIFGGIC-EPCQCFGHAESCDDVTGEC 773
Query: 340 L-CEAGFAGERCEARLCPEGLYG-------IKCDK-RCPCHLENTH---SCH---PMSGE 384
L C+ G C+ C G YG C CP ++ + + +CH +
Sbjct: 774 LNCKDHTGGPYCDK--CLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLI 831
Query: 385 C-ACKPGWSGLYCNETCSPGFYGE------ACQQICSCQNGAD------CDSVTGKC-TC 430
C C G++G C E C+ G++G+ +CQ C C + D CDS++G C C
Sbjct: 832 CDGCPVGYTGPRC-ERCAEGYFGQPSVPGGSCQP-CQCNDNLDFSIPGSCDSLSGSCLIC 889
Query: 431 APGFKGIDCSTPCPLGTYG-----INCS-SRC--GCKNDAVCSPVDGSCTCKAGWHGVDC 482
PG G C C G +G NC RC G VC G C C+A G C
Sbjct: 890 KPGTTGRYCEL-CADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRC 948
Query: 483 SIRCPSGTWGF----GCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTY 534
+C +GT+G GC + C C + G+ C G C C PG G+KC+ C G +
Sbjct: 949 D-KCKAGTFGLQSARGC-VPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCD-RCAHGYF 1004
Query: 535 GL--NCAERCDCSH-ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGA 591
C+CSH + C P TG C C P G C S CA WG + + C N +
Sbjct: 1005 NFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCS 1063
Query: 592 S-------CSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGL 644
+ C+ + G C C P F G C CS G + + P+C L
Sbjct: 1064 TVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHWNY------PRC-----------NL 1105
Query: 645 CDC-LPGFTGALCNEVCPSGRFGKNCA-----GICTCTNNGTCNPIDRSCQCYPGWIGSD 698
CDC LPG C+ K C+ G CTC N DR C PG G D
Sbjct: 1106 CDCFLPGTDATTCDSET------KKCSCSDQTGQCTCKVNVEGIHCDR---CRPGKFGLD 1156
Query: 699 CSQP 702
P
Sbjct: 1157 AKNP 1160
Score = 139 bits (350), Expect = 2e-32
Identities = 115/379 (30%), Positives = 156/379 (41%), Gaps = 72/379 (18%)
Query: 514 CTCAPGWRGEKCELPCQ------DGTYGLNCAERCDC-SHADGCHPTTGHC-RCLPGWSG 565
C C PG+ G CE C +GT E C C HA+ C TG C C G
Sbjct: 724 CQCPPGYTGSSCE-SCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGG 782
Query: 566 VHCDSVCAEGRWGP-------NCSLPCYC-------KNGASCSPDDG---ICE-CAPGFR 607
+CD C G +G +C PC C +C D IC+ C G+
Sbjct: 783 PYCDK-CLPGFYGEPTKGTSEDCQ-PCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 608 GTTCQRICSPGFYGHRC--SQTCPQCVHSSGPCHHITGLCD--------CLPGFTGALCN 657
G C+R C+ G++G +C C + I G CD C PG TG C
Sbjct: 841 GPRCER-CAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYC- 898
Query: 658 EVCPSGRFG-----KNCAGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHW 708
E+C G FG KNC C C G+ C+ C+C G C + C +
Sbjct: 899 ELCADGYFGDAVDAKNCQP-CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDK-CKAGTF 956
Query: 709 G----PNCIHTCNCHN---GAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG--KDCALIC 759
G C+ CNC++ +F G+C C PG TG C RC G++ + C
Sbjct: 957 GLQSARGCV-PCNCNSFGSKSFDCEESGQCWCQPGVTGKKC-DRCAHGYFNFQEGGCTAC 1014
Query: 760 QCQN-GADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNST-------CD 811
+C + G +CD +G+C C +G C KC T+G+ C N ST C+
Sbjct: 1015 ECSHLGNNCDPKTGRCICPPNTIGEKCS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCN 1073
Query: 812 HITGTCYCSPGWKGARCDQ 830
TG C C P + GA+C +
Sbjct: 1074 VNTGQCNCHPKFSGAKCTE 1092
Score = 135 bits (340), Expect = 2e-31
Identities = 136/520 (26%), Positives = 182/520 (35%), Gaps = 151/520 (29%)
Query: 42 VTVQESYPHPFDQIYYTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYES 101
V +Q +Y D I+ S ++ VSY T G QC PG+ S
Sbjct: 684 VLLQITYSFGMDAIFRLSSVNL-------ESAVSYPT---DGSIAAAVEVCQCPPGYTGS 733
Query: 102 -----------------GEMCVP-HC---ADKC--VHGRCIAPNTCQCEPGWGGTNCSSA 138
G +C P C A+ C V G C+ C+ GG C
Sbjct: 734 SCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECL-----NCKDHTGGPYCDKC 788
Query: 139 CDGDHWGP-----HCTSRCQCKNGALCNPITGACH-----------CAAGFRGWRCEDRC 182
G + P C C N + CH C G+ G RCE RC
Sbjct: 789 LPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCE-RC 847
Query: 183 EQGTYGN------DCHQRCQCQNG------ATCDHVTGECR-CPPGYTGAFCEDLCPPGK 229
+G +G C Q CQC + +CD ++G C C PG TG +CE LC G
Sbjct: 848 AEGYFGQPSVPGGSC-QPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCE-LCADGY 905
Query: 230 HGPQCE----QRCPCQNGG----VCHHVTGECSCPSGWMGTVCGQP-------------- 267
G + Q C C GG VCH TG+C C + G C +
Sbjct: 906 FGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCV 965
Query: 268 ---------------------CPEGRFGKNCSQ--------------ECQC-HNGGTCDA 291
C G GK C + C+C H G CD
Sbjct: 966 PCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDP 1025
Query: 292 ATGQCHCSPGYTGERCQDECPVGTYG---VLCAETCQCVNGG----KCYHVSGACLCEAG 344
TG+C C P GE+C +C T+G + C C G +C +G C C
Sbjct: 1026 KTGRCICPPNTIGEKC-SKCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPK 1084
Query: 345 FAGERCEARLCPEGLYGIKCDKRCPCHLENTH-----------SCHPMSGECACKPGWSG 393
F+G +C C G + C C L T SC +G+C CK G
Sbjct: 1085 FSGAKCTE--CSRGHWNYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEG 1142
Query: 394 LYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPG 433
++C + C PG +G + C + C T +C+ A G
Sbjct: 1143 IHC-DRCRPGKFGLDAKNPLGC-SSCYCFGTTTQCSEAKG 1180
Score = 128 bits (321), Expect = 4e-29
Identities = 127/469 (27%), Positives = 175/469 (37%), Gaps = 97/469 (20%)
Query: 447 TYGINCSSRCGCKN--DAVCSPVDGS-------CTCKAGWHGVDCSIRCP-----SGTWG 492
++G++ R N AV P DGS C C G+ G C P +GT
Sbjct: 691 SFGMDAIFRLSSVNLESAVSYPTDGSIAAAVEVCQCPPGYTGSSCESCWPRHRRVNGTIF 750
Query: 493 FGCNLTCQCL-NGGACNTLDGTC-TCAPGWRGEKCELPCQDGTYG------LNCAERCDC 544
G CQC + +C+ + G C C G C+ C G YG + C C
Sbjct: 751 GGICEPCQCFGHAESCDDVTGECLNCKDHTGGPYCD-KCLPGFYGEPTKGTSEDCQPCAC 809
Query: 545 S---HADGCHPTTGHCR--------CLPGWSGVHCDSVCAEGRWGP------NCSLPCYC 587
++ PT R C G++G C+ CAEG +G +C PC C
Sbjct: 810 PLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCER-CAEGYFGQPSVPGGSCQ-PCQC 867
Query: 588 KNG------ASCSPDDGICE-CAPGFRGTTCQRICSPGFYGHRC-SQTCPQCVHSSGP-- 637
+ SC G C C PG G C+ +C+ G++G ++ C C ++G
Sbjct: 868 NDNLDFSIPGSCDSLSGSCLICKPGTTGRYCE-LCADGYFGDAVDAKNCQPCRCNAGGSF 926
Query: 638 ---CHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRS------- 687
CH TG C+C G C++ C +G FG A C N CN
Sbjct: 927 SEVCHSQTGQCECRANVQGQRCDK-CKAGTFGLQSARGCVPCN---CNSFGSKSFDCEES 982
Query: 688 --CQCYPGWIGSDCSQPCPPAHWG---PNCIHTCNC-HNGAFCSAYDGECKCTPGWTGLY 741
C C PG G C + C ++ C C C H G C G C C P G
Sbjct: 983 GQCWCQPGVTGKKCDR-CAHGYFNFQEGGCT-ACECSHLGNNCDPKTGRCICPPNTIGEK 1040
Query: 742 CTQRCPLGFYGKDCALICQCQNGA-------DCDHISGQCTCRTGFMGRHCEQKCPSGTY 794
C+ +C +G C+ N + C+ +GQC C F G C + C G +
Sbjct: 1041 CS-KCAPNTWGHSITTGCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGAKCTE-CSRGHW 1098
Query: 795 GYGCRQICDCLNNST-------------CDHITGTCYCSPGWKGARCDQ 830
Y +CDC T C TG C C +G CD+
Sbjct: 1099 NYPRCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDR 1147
Score = 74.7 bits (182), Expect = 5e-13
Identities = 70/242 (28%), Positives = 92/242 (38%), Gaps = 74/242 (30%)
Query: 209 ECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPC 268
+C CP GY+G CE C PG + R Q GG P +GT
Sbjct: 1379 KCDCPLGYSGLSCE-ACLPGFY------RLRSQPGG---------RTPGPTLGTCV---- 1418
Query: 269 PEGRFGKNCSQECQCH-NGGTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCA----- 321
CQC+ + CD T C +C G+ C+ C +G YG++
Sbjct: 1419 -----------PCQCNGHSSLCDPETSICQNCQHHTAGDFCE-RCALGYYGIVKGLPNDC 1466
Query: 322 ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPM 381
+ C C + S +C+ E G RC A CP G G C++
Sbjct: 1467 QQCACPLISSSNNFSPSCVAE-GLDDYRCTA--CPRGYEGQYCER--------------- 1508
Query: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD----CDSVTGKCTCAPGFKGI 437
C PG++G SPG G +CQ+ C C CD VTG CTC PG G
Sbjct: 1509 -----CAPGYTG-------SPGNPGGSCQE-CECDPYGSLPVPCDPVTGFCTCRPGATGR 1555
Query: 438 DC 439
C
Sbjct: 1556 KC 1557
Score = 71.2 bits (173), Expect = 5e-12
Identities = 68/230 (29%), Positives = 91/230 (39%), Gaps = 60/230 (26%)
Query: 124 CQCEPGWGGTNCSSACDGDHW----------GPHCTS--RCQCK-NGALCNPITGAC-HC 169
C C G+ G +C + G + GP + CQC + +LC+P T C +C
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQNC 1439
Query: 170 AAGFRGWRCEDRCEQGTYG------NDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCED 223
G CE RC G YG NDC Q+C C ++ ++ + C G C
Sbjct: 1440 QHHTAGDFCE-RCALGYYGIVKGLPNDC-QQCACPLISSSNNFSPSC-VAEGLDDYRCT- 1495
Query: 224 LCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQC 283
CP G G CE+ C G+ G+ G G +C QEC+C
Sbjct: 1496 ACPRGYEGQYCER------------------CAPGYTGS-------PGNPGGSC-QECEC 1529
Query: 284 HNGGT----CDAATGQCHCSPGYTGERCQDECP-----VGTYGVLCAETC 324
G+ CD TG C C PG TG +C D C G V C + C
Sbjct: 1530 DPYGSLPVPCDPVTGFCTCRPGATGRKC-DGCKHWHAREGWECVFCGDEC 1578
Score = 65.1 bits (157), Expect = 4e-10
Identities = 63/228 (27%), Positives = 74/228 (32%), Gaps = 67/228 (29%)
Query: 384 ECACKPGWSGLYCNETCSPGFYGEACQQ-------------ICSCQNGAD-CDSVTGKCT 429
+C C G+SGL C E C PGFY Q C C + CD T C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 430 CAPGFKGIDCSTPCPLGTYGI-----NCSSRCGCKNDAVCSPVDGSCT-----------C 473
D C LG YGI N +C C + + SC C
Sbjct: 1438 NCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 474 KAGWHGVDCSIRCPSGTWGF-----GCNLTCQCLNGGA----CNTLDGTCTCAPGWRGEK 524
G+ G C RC G G G C+C G+ C+ + G CTC PG G K
Sbjct: 1498 PRGYEGQYCE-RCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 525 CELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVC 572
C DGC H GW V C C
Sbjct: 1557 C----------------------DGCK----HWHAREGWECVFCGDEC 1578
Score = 64.3 bits (155), Expect = 6e-10
Identities = 61/213 (28%), Positives = 80/213 (37%), Gaps = 62/213 (29%)
Query: 645 CDCLPGFTGALCNEVCPSG--RFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQP 702
CDC G++G C E C G R G GTC P CQC + S
Sbjct: 1380 CDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVP----CQC------NGHSSL 1428
Query: 703 CPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYG------KDCA 756
C P T C N C G +C +RC LG+YG DC
Sbjct: 1429 CDP--------ETSICQN------------CQHHTAGDFC-ERCALGYYGIVKGLPNDCQ 1467
Query: 757 LICQCQNGADCDHISGQCT-----------CRTGFMGRHCEQKCPS-----GTYGYGCRQ 800
C C + ++ S C C G+ G++CE+ P G G C++
Sbjct: 1468 Q-CACPLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQE 1526
Query: 801 ICDCLNNST----CDHITGTCYCSPGWKGARCD 829
C+C + CD +TG C C PG G +CD
Sbjct: 1527 -CECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 63/219 (28%)
Query: 671 GICTCTNNGTCNPIDRS-----CQCYPGWIGSDCSQPCPPAHWGP----------NCIHT 715
G+C C + P+D + C+C G C Q CP H P C
Sbjct: 285 GMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTEC-EA 343
Query: 716 CNCHNGAFCSAYD-------------------GEC-KCTPGWTGLYCTQRCPLGF----- 750
CNCH A YD G C CT G+ C + C GF
Sbjct: 344 CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINC-ETCTDGFFRPKG 402
Query: 751 ----YGKDCALICQCQNGADCDHI-------------SGQCTCRTGFMGRHCEQKCPSGT 793
Y + C C C + + G C C+TGF G C+ +C G
Sbjct: 403 VSPNYPRPCQ-PCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD-RCARGY 460
Query: 794 YGYGCRQICDC--LNNSTCDHITGTCYCSPGWKGARCDQ 830
GY + C+C L + D G C C +G C +
Sbjct: 461 TGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSR 499
Score = 62.0 bits (149), Expect = 3e-09
Identities = 55/182 (30%), Positives = 73/182 (40%), Gaps = 41/182 (22%)
Query: 514 CTCAPGWRGEKCELPCQDGTYGLNCAER-------------CDCS-HADGCHPTTGHCR- 558
C C G+ G CE C G Y L C C+ H+ C P T C+
Sbjct: 1380 CDCPLGYSGLSCEA-CLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 559 CLPGWSGVHCDSVCAEGRWG-----PNCSLPCYC---KNGASCSP-------DDGICECA 603
C +G C+ CA G +G PN C C + + SP DD C
Sbjct: 1439 CQHHTAGDFCER-CALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTAC 1497
Query: 604 P-GFRGTTCQRICSPGFYGHRCSQ--TCPQCVHSSG-----PCHHITGLCDCLPGFTGAL 655
P G+ G C+R C+PG+ G + +C +C PC +TG C C PG TG
Sbjct: 1498 PRGYEGQYCER-CAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRK 1556
Query: 656 CN 657
C+
Sbjct: 1557 CD 1558
Score = 53.9 bits (128), Expect = 8e-07
Identities = 69/270 (25%), Positives = 94/270 (34%), Gaps = 53/270 (19%)
Query: 332 CYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCP----------CHLENTH----S 377
CY + AC + RCE C G CD+ CP L T +
Sbjct: 289 CYGHARACPLDPATNKSRCE---CEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 378 CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN--GADCDSVTGKCTCAPGF- 434
CH + EC + + + G C+ QN G +C+ TC GF
Sbjct: 346 CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCT-QNTAGINCE------TCTDGFF 398
Query: 435 --KGIDCS-----TPC---PLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSI 484
KG+ + PC P+G+ C + A GSC CK G+ GV C
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKD---EKHARRGLAPGSCHCKTGFGGVSCD- 454
Query: 485 RCPSGTWGFGCNLTCQCLNGGACN--TLDGTCTCAPGWRGEKCELPCQDGTYGL-----N 537
RC G G+ C C G+ N G C C G C C+ G + L
Sbjct: 455 RCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCS-RCKSGFFNLQEDNWK 513
Query: 538 CAERCDCS----HADGCHPTTGHCRCLPGW 563
+ C CS + T G + + GW
Sbjct: 514 GCDECFCSGVSNRCQSSYWTYGKIQDMSGW 543
Score = 51.2 bits (121), Expect = 5e-06
Identities = 73/301 (24%), Positives = 100/301 (33%), Gaps = 60/301 (19%)
Query: 450 INCSSRCGCKNDAVCSPVDGS-----CTCKAGWHGVDCSIRCPS---GTWGFGCNLT-CQ 500
I+ C C A P+D + C C+ G C CP W G LT +
Sbjct: 281 ISVGGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTE 340
Query: 501 CLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHC-RC 559
C ACN C ++ Y N A R + G + G C C
Sbjct: 341 C---EACN----------------CHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINC 381
Query: 560 LPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGF 619
+G++C++ C +G + P P Y + C P C C P G
Sbjct: 382 TQNTAGINCET-CTDGFFRPKGVSPNYPR---PCQP----CHCDP------------IGS 421
Query: 620 YGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNG 679
C + P G C C GF G C+ C G G C C+ G
Sbjct: 422 LNEVCVKDEKHARRGLAP-----GSCHCKTGFGGVSCDR-CARGYTGYPDCKACNCSGLG 475
Query: 680 TCN--PIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGW 737
+ N P C C G DCS+ C + + C + FCS C+ + W
Sbjct: 476 SKNEDPCFGPCICKENVEGGDCSR-CKSGFFNLQEDNWKGC-DECFCSGVSNRCQ-SSYW 532
Query: 738 T 738
T
Sbjct: 533 T 533
Score = 48.9 bits (115), Expect = 3e-05
Identities = 65/232 (28%), Positives = 78/232 (33%), Gaps = 57/232 (24%)
Query: 413 CSCQN---GADCDSVTGKCTCAPGFKGIDCSTPCPLGTY-------GINCSSRCG-CKND 461
C C++ G CD C PGF P GT+ NC + C D
Sbjct: 307 CECEHNTCGDSCDQ------CCPGFH----QKPWRAGTFLTKTECEACNCHGKAEECYYD 356
Query: 462 AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWR 521
+ + S + + G I C T G C TC G+
Sbjct: 357 ENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE------------------TCTDGFF 398
Query: 522 GEK-----CELPCQ----DGTYGLNCAERCDCSHAD-GCHPTTGHCRCLPGWSGVHCDSV 571
K PCQ D LN D HA G P G C C G+ GV CD
Sbjct: 399 RPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAP--GSCHCKTGFGGVSCDR- 455
Query: 572 CAEGRWG-PNCSLPCYCKNGASCSPDD--GICECAPGFRGTTCQRICSPGFY 620
CA G G P+C C C S + D G C C G C R C GF+
Sbjct: 456 CARGYTGYPDCK-ACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF 505
Score = 47.8 bits (112), Expect = 6e-05
Identities = 47/182 (25%), Positives = 59/182 (32%), Gaps = 57/182 (31%)
Query: 93 QCCPGFYESG------------EMCVPH-CADKC--------------VHGRCIAPNTC- 124
QCCPGF++ E C H A++C + G+ I C
Sbjct: 320 QCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCI 379
Query: 125 QCEPGWGGTNCSSACDG----DHWGPHCTSRCQCKNGALCNPI----------------- 163
C G NC + DG P+ CQ C+PI
Sbjct: 380 NCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQ---PCHCDPIGSLNEVCVKDEKHARRG 436
Query: 164 --TGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ--NGATCDHVTGECRCPPGYTGA 219
G+CHC GF G C DRC +G G + C C D G C C G
Sbjct: 437 LAPGSCHCKTGFGGVSC-DRCARGYTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGG 495
Query: 220 FC 221
C
Sbjct: 496 DC 497
Score = 46.6 bits (109), Expect = 1e-04
Identities = 36/120 (30%), Positives = 46/120 (38%), Gaps = 17/120 (14%)
Query: 95 CPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQC 154
C E+CV D+ R +AP +C C+ G+GG +C G P C + C C
Sbjct: 416 CDPIGSLNEVCVK---DEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKA-CNC 471
Query: 155 KNGALCN--PITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRC 212
N P G C C G C RC+ G + Q N CD EC C
Sbjct: 472 SGLGSKNEDPCFGPCICKENVEGGDC-SRCKSGFF------NLQEDNWKGCD----ECFC 520
Score = 42.0 bits (97), Expect = 0.003
Identities = 69/272 (25%), Positives = 83/272 (30%), Gaps = 76/272 (27%)
Query: 102 GEMCVPHC-ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP----------HCTS 150
G MC+ + A C + C+CE G +C C G H P C +
Sbjct: 284 GGMCICYGHARACPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEA 343
Query: 151 RCQCKNGA-------------LCNPITG-------ACHCAAGFRGWRCEDRCEQG----- 185
C C A L I G +C G CE C G
Sbjct: 344 -CNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCE-TCTDGFFRPK 401
Query: 186 ----TYGNDCHQRCQCQNGATCDHV-------------TGECRCPPGYTGAFCEDLCPPG 228
Y C Q C C + + V G C C G+ G C D C G
Sbjct: 402 GVSPNYPRPC-QPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC-DRCARG 459
Query: 229 KHG-PQCEQRCPCQNGGVCHH--VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN 285
G P C + C C G + G C C G C + C G F Q N
Sbjct: 460 YTGYPDC-KACNCSGLGSKNEDPCFGPCICKENVEGGDCSR-CKSGFF------NLQEDN 511
Query: 286 GGTCDAATGQCHCSPGYTGERCQDECPVGTYG 317
CD +C CS RCQ TYG
Sbjct: 512 WKGCD----ECFCSG--VSNRCQSS--YWTYG 535
Score = 36.2 bits (82), Expect = 0.18
Identities = 38/157 (24%), Positives = 61/157 (38%), Gaps = 35/157 (22%)
Query: 730 ECKCTPGWTGLYCTQRCPLGFY-------GK------DCALICQCQNGAD-CDHISGQC- 774
+C C G++GL C + C GFY G+ + CQC + CD + C
Sbjct: 1379 KCDCPLGYSGLSC-EACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQ 1437
Query: 775 TCRTGFMGRHCEQKCPSGTYGY------GCRQICDCLNNSTCDHITGTCY---------- 818
C+ G CE +C G YG C+Q C C S+ ++ + +C
Sbjct: 1438 NCQHHTAGDFCE-RCALGYYGIVKGLPNDCQQ-CACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 819 -CSPGWKGARCDQAGVIIVGNLNSLSRTSTALPADSY 854
C G++G C++ G+ + + D Y
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPY 1532
Score = 35.0 bits (79), Expect = 0.41
Identities = 28/96 (29%), Positives = 36/96 (37%), Gaps = 14/96 (14%)
Query: 93 QCCPGFYESGEMCVPHC-ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPH---- 147
QC S P C A+ RC A C G+ G C G P
Sbjct: 1468 QCACPLISSSNNFSPSCVAEGLDDYRCTA-----CPRGYEGQYCERCAPGYTGSPGNPGG 1522
Query: 148 CTSRCQCKN-GAL---CNPITGACHCAAGFRGWRCE 179
C+C G+L C+P+TG C C G G +C+
Sbjct: 1523 SCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 178 bits (452), Expect = 2e-44
Identities = 196/763 (25%), Positives = 283/763 (37%), Gaps = 188/763 (24%)
Query: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE 183
C C + G C D +C LC ++ C+C+ R R + CE
Sbjct: 590 CSCSLSYIGRLCVVNVD------YCLGNHSISVHGLCLALSHNCNCSGLQRYER--NICE 641
Query: 184 QGTYGNDCHQRCQCQNGATCDHVTGEC--RCPPGYTGAFCE-DLCPPGKHGPQCEQRCPC 240
T DC + C+NG T H+ G +C PG+ G CE D+ H PC
Sbjct: 642 IDT--EDC-KSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASH--------PC 690
Query: 241 QNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSP 300
+NG C G C C + +G +C C+P
Sbjct: 691 KNGATCIDQPGNYFC--------------------QCVPPFKVVDGFSC-------LCNP 723
Query: 301 GYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPE 357
GY G RC+ D+C + C C K H+S C+C + + G CE
Sbjct: 724 GYVGIRCEQDIDDCILNA----CEHNSTC----KDLHLSYQCVCLSDWEGNFCEQE---- 771
Query: 358 GLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQN 417
+C K PC +T + S C C GW+G C+E + C C N
Sbjct: 772 ---SNEC-KMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINE------CDSD-PCMN 820
Query: 418 GADC--DSVTGK--CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC-SPVDGS-- 470
G C ++ G+ C C P + G C Y + C+N++ C + VD +
Sbjct: 821 GGLCHESTIPGQFVCLCPPLYTGQFCHQ-----RYNLCDLLHNPCRNNSTCLALVDANQH 875
Query: 471 CTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRGEKCEL- 527
C C+ + G +C I C L C + G C + C C PG+ G CE+
Sbjct: 876 CICREEFEGKNCEIDVKD------C-LFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIE 928
Query: 528 -------PCQDGTYGLNCAER--CDCS---HADGCHPTTGHCRCLPGWSGVHC------- 568
PC++ ++ R C+C H C C+ P +C
Sbjct: 929 INECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGY 988
Query: 569 DSVCAEGRWGPNCSLPCYCKNGASCSPD----DGICECAPGFRGTTCQRICSPGFYGHRC 624
+ +CA G G NC + N C + DG+C G TC C GF+G C
Sbjct: 989 NCLCAPGYTGINCEI-----NLDECLSEPCLHDGVC--IDGINHYTCD--CKSGFFGTHC 1039
Query: 625 SQTCPQCVHSSGPCHH--ITGL-----CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTN 677
C+ S PC H T L C C T C +C I C N
Sbjct: 1040 ETNANDCL--SNPCLHGRCTELINEYPCSCDADGTSTQCKIKI------NDCTSI-PCMN 1090
Query: 678 NGTCNPIDR--SCQCYPGWIGSDCSQPCPPAHWGPNC----IHTCNCHNGAFCSAYDG-- 729
G C +C C G+ G+ C + NC +++ C NG C G
Sbjct: 1091 EGFCQKSAHGFTCICPRGYTGAYCEKSID------NCAEPELNSVICLNGGICVDGPGHT 1144
Query: 730 -ECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC-DHISGQ-CTCRTGFMGRHCE 786
+C+C PG++G +C +C+ C +GADC DHI+G C C+ G+ G HCE
Sbjct: 1145 FDCRCLPGFSGQFCEINI------NECSS-SPCLHGADCEDHINGYVCKCQPGWSGHHCE 1197
Query: 787 QKCPSGTYGYGCRQICDCLNNSTCDHIT------GTCYCSPGW 823
+ +C+ NS + TC C+PG+
Sbjct: 1198 NE-------------LECIPNSCVHELCMENEPGSTCLCTPGF 1227
Score = 156 bits (395), Expect = 9e-38
Identities = 220/927 (23%), Positives = 317/927 (34%), Gaps = 228/927 (24%)
Query: 33 VCSHWES----YSVTVQESYPHPFD-------QIYYTSCTDILNWFKCTRHRVSYRTAYR 81
V S W S Y +TV S P P + C + L+ C+ H A+
Sbjct: 136 VNSKWLSVGTHYFITVMASGPSPCPLGLRLNVTVKQQFCQESLSSEFCSGHGKCLSEAW- 194
Query: 82 HGEKTMYRRKSQCCPGFYESGEMC--VPHCADKCV--HGRCIAPNT--------CQCEPG 129
KT C P F SG+ C + C+ K +G CI C C P
Sbjct: 195 --SKTY---SCHCQPPF--SGKYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPP 247
Query: 130 WGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCE------ 183
+ G NCS PH C N + C C F G CE +
Sbjct: 248 FTGKNCSEII--GQCQPHVCFHGNCSN---ITSNSFICECDEQFSGPFCEVSAKPCVSLL 302
Query: 184 ----------QGTYGNDCHQRCQ---------------CQNGATCDHVTGE--CRCPPGY 216
Y +C + CQNG C ++ + C C P +
Sbjct: 303 FWKRGICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIF 362
Query: 217 TGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGR-F 273
T C+ + CE P +N C + CSC SG+ C + +
Sbjct: 363 TDLLCKSI------QTSCES-FPLRNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLL 415
Query: 274 GKNCSQECQCHNGGTCDAATGQCHCSPGYTGERC---QDECPVGTYGVLCAETCQ--CVN 328
NC E C N + C PG T C ++ + + C T C +
Sbjct: 416 SINCLNEEWCFN----IIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFHGICQD 471
Query: 329 GGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACK 388
G L AG GE+C+ + C + + T+ P +C
Sbjct: 472 KGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTE------DATYVNDPEDNNSSC- 524
Query: 389 PGWSGLYCNETCSPGFYGEACQQICSCQNGADC----DSVTGKCTCAPGFKGIDCSTPCP 444
W F E ++IC+ NG C DS + C + G
Sbjct: 525 --W------------FPHEGTKEICA--NGCSCLSEEDSQEYRYLCFLRWAG-------N 561
Query: 445 LGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCL 502
+ C+++AVC C+C + G C + ++
Sbjct: 562 MYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISV----- 616
Query: 503 NGGACNTLDGTCTCAPGWRGEK--CELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCL 560
G C L C C+ R E+ CE+ +D +C +H G +C+
Sbjct: 617 -HGLCLALSHNCNCSGLQRYERNICEIDTED-CKSASCKNGTTSTHLRGYF----FRKCV 670
Query: 561 PGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC--SPDDGICECAPGFR---GTTCQRIC 615
PG+ G C+ E P CKNGA+C P + C+C P F+ G +C +C
Sbjct: 671 PGFKGTQCEIDIDECASHP-------CKNGATCIDQPGNYFCQCVPPFKVVDGFSC--LC 721
Query: 616 SPGFYGHRCSQTCPQCV------HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
+PG+ G RC Q C+ +S+ H++ C CL + G C + N
Sbjct: 722 NPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSDWEGNFCEQ-------ESNE 774
Query: 670 AGICTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC--S 725
+ C NN TC + +S C+C GW G +CS+ P C NG C S
Sbjct: 775 CKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECDSDP-------CMNGGLCHES 827
Query: 726 AYDGE--CKCTPGWTGLYCTQR----------------------------CPLGFYGKDC 755
G+ C C P +TG +C QR C F GK+C
Sbjct: 828 TIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNC 887
Query: 756 ------ALICQCQNGADCDHI--SGQCTCRTGFMGRHCE---QKCPSGTYGYGCRQICDC 804
L CQ+ DC+ + + +C CR GF G CE +C S C
Sbjct: 888 EIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSSE----------PC 937
Query: 805 LNNSTCDHITGT--CYCSPGWKGARCD 829
NN TC +T C C P + G C+
Sbjct: 938 KNNGTCVDLTNRFFCNCEPEYHGPFCE 964
Score = 50.1 bits (118), Expect = 1e-05
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 13/80 (16%)
Query: 671 GICTCTNNGTC--NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFC---S 725
G TC N G C N SC+C P W G+ C+Q +C++ C + + C
Sbjct: 2880 GYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQ 2931
Query: 726 AYDGECKCTPGWTGLYCTQR 745
++ C CT GW G YC +
Sbjct: 2932 SFSYSCLCTLGWVGRYCENK 2951
Score = 48.5 bits (114), Expect = 4e-05
Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 12/77 (15%)
Query: 675 CTNNGTCNPIDRS--CQCYPGWIGSDCSQ---PCPPAHWGPNCIHTCNCHNGAFCSA--Y 727
C N GTC S C C GW GS C++ C P H P+ +C GA C + +
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPH 2673
Query: 728 DGECKCTPGWTGLYCTQ 744
C C G TG+YC Q
Sbjct: 2674 GYTCFCPLGTTGIYCEQ 2690
Score = 43.5 bits (101), Expect = 0.001
Identities = 27/72 (37%), Positives = 30/72 (41%), Gaps = 13/72 (18%)
Query: 116 GRCIAPNT---CQCEPGWGGTNCS---SACDGDHWGPHCTSRCQCKNGALC--NPITGAC 167
G CI T C C GW G+ C+ S CD +H PH C GA C P C
Sbjct: 2623 GTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH-----HCSRGATCISLPHGYTC 2677
Query: 168 HCAAGFRGWRCE 179
C G G CE
Sbjct: 2678 FCPLGTTGIYCE 2689
Score = 42.7 bits (99), Expect = 0.002
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 15/76 (19%)
Query: 501 CLNGGACNTLDGT---CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG-- 555
C NGG C T++GT C C P W G C ++C C H C P
Sbjct: 2884 CRNGGEC-TVNGTTFSCRCLPDWAGNTC-------NQSVSCLNNL-CLHQSLCIPDQSFS 2934
Query: 556 -HCRCLPGWSGVHCDS 570
C C GW G +C++
Sbjct: 2935 YSCLCTLGWVGRYCEN 2950
Score = 42.0 bits (97), Expect = 0.003
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 18/94 (19%)
Query: 180 DRCEQGTYGNDCH----QRCQCQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHGPQ 233
D G +CH C+N TC D+ C CP Y+G C+
Sbjct: 2323 DEARHGKNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--------FAS 2374
Query: 234 CEQRCPCQNGGVCHHVTGE---CSCPSGWMGTVC 264
CE PC NG C +G C CP G G +C
Sbjct: 2375 CENN-PCGNGATCVPKSGTDIVCLCPYGRSGPLC 2407
Score = 39.7 bits (91), Expect = 0.016
Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 29/113 (25%)
Query: 343 AGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNE---T 399
AG + +C A C +KC C T S C C GW G +C E T
Sbjct: 2602 AGRSVGQCHASPCSL----MKCGNGGTCIESGT------SVYCNCTTGWKGSFCTETVST 2651
Query: 400 CSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINC 452
C P C GA C S+ TC CPLGT GI C
Sbjct: 2652 CDPEH-----DPPHHCSRGATCISLPHGYTCF-----------CPLGTTGIYC 2688
Score = 39.7 bits (91), Expect = 0.016
Identities = 27/80 (33%), Positives = 33/80 (41%), Gaps = 16/80 (20%)
Query: 196 QCQNGATC--DHVTGECRCPPGYTGAFCED---LCPPGKHGPQCEQRCPCQNGGVC---- 246
+C NG TC + C C G+ G+FC + C P +H P C G C
Sbjct: 2618 KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDP-EHDPPHH----CSRGATCISLP 2672
Query: 247 HHVTGECSCPSGWMGTVCGQ 266
H T C CP G G C Q
Sbjct: 2673 HGYT--CFCPLGTTGIYCEQ 2690
Score = 38.9 bits (89), Expect = 0.028
Identities = 25/74 (33%), Positives = 29/74 (39%), Gaps = 6/74 (8%)
Query: 718 CHNGAFC--SAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHI--SGQ 773
C NG C S C CT GW G +CT+ D C GA C +
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP--HHCSRGATCISLPHGYT 2676
Query: 774 CTCRTGFMGRHCEQ 787
C C G G +CEQ
Sbjct: 2677 CFCPLGTTGIYCEQ 2690
Score = 38.9 bits (89), Expect = 0.028
Identities = 24/81 (29%), Positives = 31/81 (38%), Gaps = 13/81 (16%)
Query: 718 CHNGAFCSAYDG--ECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADC---DHISG 772
C NG C+ C+C P W G C Q L C + + C S
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--------CLNNLCLHQSLCIPDQSFSY 2935
Query: 773 QCTCRTGFMGRHCEQKCPSGT 793
C C G++GR+CE K T
Sbjct: 2936 SCLCTLGWVGRYCENKTSFST 2956
Score = 38.5 bits (88), Expect = 0.037
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 6/77 (7%)
Query: 150 SRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVT 207
S +C NG C + + C+C G++G C + +D C GATC +
Sbjct: 2615 SLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS--RGATCISLP 2672
Query: 208 G--ECRCPPGYTGAFCE 222
C CP G TG +CE
Sbjct: 2673 HGYTCFCPLGTTGIYCE 2689
Score = 38.5 bits (88), Expect = 0.037
Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 13/85 (15%)
Query: 414 SCQNGADC--DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG-- 469
+C+NG +C + T C C P + G C+ ++C + C + ++C P
Sbjct: 2883 TCRNGGECTVNGTTFSCRCLPDWAGNTCNQ-------SVSCLNNL-CLHQSLCIPDQSFS 2934
Query: 470 -SCTCKAGWHGVDCSIRCPSGTWGF 493
SC C GW G C + T F
Sbjct: 2935 YSCLCTLGWVGRYCENKTSFSTAKF 2959
Score = 38.1 bits (87), Expect = 0.048
Identities = 23/78 (29%), Positives = 31/78 (39%), Gaps = 7/78 (8%)
Query: 553 TTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC--SPDDGICECAPGFRGTT 610
T+ +C C GW G C + P P +C GA+C P C C G G
Sbjct: 2630 TSVYCNCTTGWKGSFCTETVS--TCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIY 2687
Query: 611 CQR---ICSPGFYGHRCS 625
C++ I P F + S
Sbjct: 2688 CEQALSISDPSFRSNELS 2705
Score = 37.7 bits (86), Expect = 0.063
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 23/89 (25%)
Query: 240 CQNGGVCHH--VTGECSCPSGWMGTVCGQPCPEGRFGKNCSQE----CQCHNGGTCDAAT 293
C NGG C + C+C +GW G+ C + C E C G TC
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETV------STCDPEHDPPHHCSRGATC---- 2668
Query: 294 GQCHCSPGYTGERCQDECPVGTYGVLCAE 322
GYT C CP+GT G+ C +
Sbjct: 2669 --ISLPHGYT---C--FCPLGTTGIYCEQ 2690
Score = 36.6 bits (83), Expect = 0.14
Identities = 26/93 (27%), Positives = 37/93 (39%), Gaps = 23/93 (24%)
Query: 751 YGKDCALICQCQNGADC--DHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD----- 803
+ C+L+ +C NG C S C C TG+ G C + + CD
Sbjct: 2610 HASPCSLM-KCGNGGTCIESGTSVYCNCTTGWKGSFCTETVST----------CDPEHDP 2658
Query: 804 ---CLNNSTCDHITG--TCYCSPGWKGARCDQA 831
C +TC + TC+C G G C+QA
Sbjct: 2659 PHHCSRGATCISLPHGYTCFCPLGTTGIYCEQA 2691
Score = 36.2 bits (82), Expect = 0.18
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 9/102 (8%)
Query: 260 MGTVCGQPCPEGRFGKNCSQEC---QCHNGGTC--DAATGQCHCSPGYTGERCQDECPVG 314
+G G P G+ + C +C NGGTC + C+C+ G+ G C + V
Sbjct: 2593 LGNPEGHPNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE--TVS 2650
Query: 315 TYGVLCAETCQCVNGGKCYHV--SGACLCEAGFAGERCEARL 354
T C G C + C C G G CE L
Sbjct: 2651 TCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 36.2 bits (82), Expect = 0.18
Identities = 29/114 (25%), Positives = 38/114 (33%), Gaps = 29/114 (25%)
Query: 292 ATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYH--VSGACLCEAGFAGER 349
+ GQCH SP +C NGG C S C C G+ G
Sbjct: 2605 SVGQCHASP--------------------CSLMKCGNGGTCIESGTSVYCNCTTGWKGS- 2643
Query: 350 CEARLCPEGLYGIKCDKRCPCHLENTHSCH--PMSGECACKPGWSGLYCNETCS 401
C E + + P H +C P C C G +G+YC + S
Sbjct: 2644 ----FCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
Score = 36.2 bits (82), Expect = 0.18
Identities = 24/77 (31%), Positives = 32/77 (41%), Gaps = 19/77 (24%)
Query: 544 CSHADGC--HPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPC---YCKNGASCSPDDG 598
C + C + TT CRCLP W+G C N S+ C C + + C PD
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTC-----------NQSVSCLNNLCLHQSLCIPDQS 2932
Query: 599 I---CECAPGFRGTTCQ 612
C C G+ G C+
Sbjct: 2933 FSYSCLCTLGWVGRYCE 2949
Score = 35.8 bits (81), Expect = 0.24
Identities = 26/80 (32%), Positives = 32/80 (40%), Gaps = 13/80 (16%)
Query: 763 NGADCDHIS-GQCTCRTG----FMGRHCEQKCPSGTYGYGCRQICDCLNN-----STC-- 810
N DCD + G TCR G G +C G C Q CLNN S C
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIP 2929
Query: 811 -DHITGTCYCSPGWKGARCD 829
+ +C C+ GW G C+
Sbjct: 2930 DQSFSYSCLCTLGWVGRYCE 2949
Score = 35.4 bits (80), Expect = 0.31
Identities = 26/89 (29%), Positives = 34/89 (38%), Gaps = 14/89 (15%)
Query: 581 CSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHH 640
CSL C NG +C GT+ C+ G+ G C++T C P HH
Sbjct: 2614 CSL-MKCGNGGTCIES-----------GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHH 2661
Query: 641 ITGLCDCLPGFTGALCNEVCPSGRFGKNC 669
+ C+ G C CP G G C
Sbjct: 2662 CSRGATCISLPHGYTC--FCPLGTTGIYC 2688
Score = 35.0 bits (79), Expect = 0.41
Identities = 29/104 (27%), Positives = 39/104 (37%), Gaps = 31/104 (29%)
Query: 131 GGTNCSSACDGDHWGPHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYG 188
GG+N CDG G + C+NG C N T +C C + G
Sbjct: 2867 GGSNVGD-CDGTACGYNT-----CRNGGECTVNGTTFSCRCLPDWAG------------- 2907
Query: 189 NDCHQRCQCQNGATCDH---------VTGECRCPPGYTGAFCED 223
N C+Q C N C H + C C G+ G +CE+
Sbjct: 2908 NTCNQSVSCLNNL-CLHQSLCIPDQSFSYSCLCTLGWVGRYCEN 2950
Score = 33.9 bits (76), Expect = 0.91
Identities = 20/78 (25%), Positives = 30/78 (38%), Gaps = 7/78 (8%)
Query: 240 CQNGGVC--HHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCH 297
C+NGG C + T C C W G C Q C + C + + C
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPD---QSFSYSCL 2938
Query: 298 CSPGYTGERCQDECPVGT 315
C+ G+ G C+++ T
Sbjct: 2939 CTLGWVGRYCENKTSFST 2956
Score = 33.9 bits (76), Expect = 0.91
Identities = 23/79 (29%), Positives = 28/79 (35%), Gaps = 12/79 (15%)
Query: 326 CVNGGKCYHVSG---ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMS 382
C NGG+C V+G +C C +AG C + C H S
Sbjct: 2884 CRNGGECT-VNGTTFSCRCLPDWAGNTCNQ--------SVSCLNNLCLHQSLCIPDQSFS 2934
Query: 383 GECACKPGWSGLYCNETCS 401
C C GW G YC S
Sbjct: 2935 YSCLCTLGWVGRYCENKTS 2953
Score = 33.9 bits (76), Expect = 0.91
Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 14/77 (18%)
Query: 116 GRCIAPNT---CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNP---ITGACHC 169
G C T C+C P W G C+ + C + C + +LC P + +C C
Sbjct: 2888 GECTVNGTTFSCRCLPDWAGNTCNQSVS-------CLNNL-CLHQSLCIPDQSFSYSCLC 2939
Query: 170 AAGFRGWRCEDRCEQGT 186
G+ G CE++ T
Sbjct: 2940 TLGWVGRYCENKTSFST 2956
Score = 33.5 bits (75), Expect = 1.2
Identities = 25/88 (28%), Positives = 33/88 (37%), Gaps = 25/88 (28%)
Query: 495 CNLTCQCLNGGACNTLDGT---CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCH 551
C+L +C NGG C GT C C GW+G C CD H H
Sbjct: 2614 CSLM-KCGNGGTCIE-SGTSVYCNCTTGWKGSFC----------TETVSTCDPEHDPPHH 2661
Query: 552 PTTG----------HCRCLPGWSGVHCD 569
+ G C C G +G++C+
Sbjct: 2662 CSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 33.1 bits (74), Expect = 1.5
Identities = 16/41 (39%), Positives = 21/41 (51%), Gaps = 8/41 (19%)
Query: 277 CSQECQCHNGGTCDA-------ATGQCHCSPGYTGERCQDE 310
C Q+ CHNGGTC A + QC C +TG C+ +
Sbjct: 2103 CQQDV-CHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 33.1 bits (74), Expect = 1.5
Identities = 27/94 (28%), Positives = 34/94 (36%), Gaps = 16/94 (17%)
Query: 445 LGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGW----HGVDCSIRCPSGTWGFGCNLTCQ 500
L +G S G + C G TC+ G +G S RC G CN +
Sbjct: 2860 LTEFGAKGGSNVGDCDGTAC----GYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS 2915
Query: 501 CLNG-----GAC---NTLDGTCTCAPGWRGEKCE 526
CLN C + +C C GW G CE
Sbjct: 2916 CLNNLCLHQSLCIPDQSFSYSCLCTLGWVGRYCE 2949
Score = 32.7 bits (73), Expect = 2.0
Identities = 22/79 (27%), Positives = 28/79 (35%), Gaps = 25/79 (31%)
Query: 197 CQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHH------ 248
C+NG C + T CRC P + G C Q C N +C H
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWA-------------GNTCNQSVSCLN-NLCLHQSLCIP 2929
Query: 249 ---VTGECSCPSGWMGTVC 264
+ C C GW+G C
Sbjct: 2930 DQSFSYSCLCTLGWVGRYC 2948
Score = 32.3 bits (72), Expect = 2.6
Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 10/73 (13%)
Query: 789 CPSGTYGYG-CRQICDCLNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNSLS-RTS 846
C GY CR +C N T T +C C P W G C+Q+ V LN+L S
Sbjct: 2874 CDGTACGYNTCRNGGECTVNGT----TFSCRCLPDWAGNTCNQS----VSCLNNLCLHQS 2925
Query: 847 TALPADSYQIGAI 859
+P S+ +
Sbjct: 2926 LCIPDQSFSYSCL 2938
Score = 32.0 bits (71), Expect = 3.4
Identities = 23/76 (30%), Positives = 29/76 (38%), Gaps = 16/76 (21%)
Query: 154 CKNGALC--NPITGACHCAAGFRGWRCE-DRCEQGTYGNDCHQRCQCQNGATCDHVTGE- 209
C+N C + C C + G C+ CE C NGATC +G
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFASCENNP----------CGNGATCVPKSGTD 2393
Query: 210 --CRCPPGYTGAFCED 223
C CP G +G C D
Sbjct: 2394 IVCLCPYGRSGPLCTD 2409
Score = 32.0 bits (71), Expect = 3.4
Identities = 18/58 (31%), Positives = 23/58 (39%), Gaps = 11/58 (18%)
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNP---IDRSCQCYPGWIGSDC 699
C CLP + G CN+ +C C + C P SC C GW+G C
Sbjct: 2899 CRCLPDWAGNTCNQ-------SVSCLN-NLCLHQSLCIPDQSFSYSCLCTLGWVGRYC 2948
Score = 31.6 bits (70), Expect = 4.5
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 7/37 (18%)
Query: 193 QRCQCQNGATCDH-------VTGECRCPPGYTGAFCE 222
Q+ C NG TC V+ +C CP +TG FCE
Sbjct: 2104 QQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE 2140
Score = 31.2 bits (69), Expect = 5.9
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 13/74 (17%)
Query: 587 CKNGASCSPDDGI--CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSS--GPCHHIT 642
C+NG C+ + C C P + G TC + S C C+H S P +
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-------CLNNL--CLHQSLCIPDQSFS 2934
Query: 643 GLCDCLPGFTGALC 656
C C G+ G C
Sbjct: 2935 YSCLCTLGWVGRYC 2948
Score = 30.8 bits (68), Expect = 7.7
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 7/45 (15%)
Query: 227 PGKHGPQCEQRCPCQNGGVCHH-------VTGECSCPSGWMGTVC 264
P P Q+ C NGG CH V+ +C CP + G C
Sbjct: 2095 PSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFC 2139
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 175 bits (443), Expect = 3e-43
Identities = 153/485 (31%), Positives = 197/485 (40%), Gaps = 108/485 (22%)
Query: 124 CQCEPGWGGTNCSSAC------DGDHWGPHCTSRCQCK-NGALCNPITGAC-HCAAGFRG 175
C+C G+ GT+C S DG +G C C+C + A CN + G C CA G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQP-CECHGHAAECN-VHGVCIACAHNTTG 766
Query: 176 WRCEDRCEQGTYGN-------DCHQRCQCQNGATCDHVTGECR-----------CPPGYT 217
CE +C G YG DC Q C C ++ + C C PGY+
Sbjct: 767 VHCE-QCLPGFYGEPSRGTPGDC-QPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 218 GAFCEDLCPPGKHGPQC---EQRCPCQ--------NGGVCHHVTGEC-SCPSGWMGTVCG 265
GA+CE C G +G E PC G C VTGEC C G C
Sbjct: 825 GAWCER-CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC- 882
Query: 266 QPCPEGRFG-----KNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTY 316
+ C +G +G KNC + C+CH G+ C TG C C P TG++C D+C G Y
Sbjct: 883 ERCADGFYGDAVTAKNC-RACECHVKGSHSAVCHLETGLCDCKPNVTGQQC-DQCLHGYY 940
Query: 317 GVLCAETCQCVNGGKCYHVS------GACLCEAGFAGERCEARLCPEGLYGIKCDKRCPC 370
G+ C+ N VS G C C G AG+RC+ C G Y + PC
Sbjct: 941 GLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR--CAHGFYAYQDGSCTPC 998
Query: 371 HLENT-HSCHPMSGECACKPGWSGLYCNETCSPGFYG---EACQQICSC----QNGADCD 422
+T ++C P +GEC C P G+ C E C G +G E Q C+C CD
Sbjct: 999 DCPHTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCD 1057
Query: 423 SVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
VTG C C F G C CS G ++ C P DC
Sbjct: 1058 VVTGHCQCKSKFGGRACD----------QCS--LGYRDFPDCVP-------------CDC 1092
Query: 483 SIRCPSGTWGFGCNLTCQCLNGGACNTLD--GTCTCAPGWRGEKCELPCQDGTYGLNCAE 540
+R GT G CN L G C ++ G C C G +C C++GT+ L
Sbjct: 1093 DLR---GTSGDACN-----LEQGLCGCVEETGACPCKENVFGPQCN-ECREGTFALRADN 1143
Query: 541 RCDCS 545
CS
Sbjct: 1144 PLGCS 1148
Score = 152 bits (383), Expect = 2e-36
Identities = 143/479 (29%), Positives = 183/479 (38%), Gaps = 105/479 (21%)
Query: 339 CLCEAGFAGERCEARLCPEGLY---GIKCDKRC-PCHLENTHSCHPMSGEC-------AC 387
C C G+ G CE+ C G Y GI C PC CH + EC AC
Sbjct: 709 CECPQGYTGTSCES--CLSGYYRVDGILFGGICQPCE------CHGHAAECNVHGVCIAC 760
Query: 388 KPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGT 447
+G++C E C PGFYGE S DC CA CPL
Sbjct: 761 AHNTTGVHC-EQCLPGFYGEP-----SRGTPGDCQP------CA-----------CPLTI 797
Query: 448 YGINCSSRCGCKN--DAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGF------GCNLTC 499
N S C + + VC C G+ G C RC G +G C + C
Sbjct: 798 ASNNFSPTCHLNDGDEVVCD------WCAPGYSGAWCE-RCADGYYGNPTVPGESC-VPC 849
Query: 500 QCLNG------GACNTLDGTCT-CAPGWRGEKCELPCQDGTYG-----LNCAERCDC--- 544
C G C+++ G C C G CE C DG YG NC C+C
Sbjct: 850 DCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNC-RACECHVK 907
Query: 545 -SHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCS---LPCYCKNGASCSP---DD 597
SH+ CH TG C C P +G CD C G +G + PC C S S D+
Sbjct: 908 GSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDE 966
Query: 598 GICECAPGFRGTTCQRICSPGFYGHRCSQTCP-QCVHSSGPCHHITGLCDCLPGFTGALC 656
G C C PG G C R C+ GFY ++ P C H+ C TG C C P G C
Sbjct: 967 GQCHCVPGVAGKRCDR-CAHGFYAYQDGSCTPCDCPHTQNTCDPETGECVCPPHTQGVKC 1025
Query: 657 NEVCPSGRFGKNC---AGICTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHWG 709
E C G +G + C C+ G+ C+ + CQC + G C Q
Sbjct: 1026 EE-CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQCSLGYRDF 1084
Query: 710 PNCIHTCNCH----NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNG 764
P+C+ C+C +G C+ G C C C + +G C +C+ G
Sbjct: 1085 PDCV-PCDCDLRGTSGDACNLEQGLCGCVEETGACPCKE----NVFGPQCN---ECREG 1135
Score = 151 bits (381), Expect = 4e-36
Identities = 131/452 (28%), Positives = 166/452 (36%), Gaps = 87/452 (19%)
Query: 94 CCPGFYES-----GEMCVP-----HCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDG-- 141
C G+Y G +C P H A+ VHG CIA C G +C G
Sbjct: 723 CLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIA-----CAHNTTGVHCEQCLPGFY 777
Query: 142 ---DHWGPHCTSRCQCKNGALCNPITGACH-----------CAAGFRGWRCEDRCEQGTY 187
P C C N + CH CA G+ G CE RC G Y
Sbjct: 778 GEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCE-RCADGYY 836
Query: 188 GN-----------DCHQRCQCQNGATCDHVTGEC-RCPPGYTGAFCEDLCPPGKHGP--- 232
GN DC CD VTGEC +C GA CE C G +G
Sbjct: 837 GNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE-RCADGFYGDAVT 895
Query: 233 -----QCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHN-- 285
CE + VCH TG C C G C Q C G +G + C+ N
Sbjct: 896 AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCS 954
Query: 286 --GGTCDAAT--GQCHCSPGYTGERCQDECPVGTYGVL--CAETCQCVN-GGKCYHVSGA 338
G D T GQCHC PG G+RC D C G Y C C + C +G
Sbjct: 955 VAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGE 1013
Query: 339 CLCEAGFAGERCEARLCPEGLYGIKCD---KRCPCHLENT--HSCHPMSGECACKPGWSG 393
C+C G +CE C +G +G + + C C L + H C ++G C CK + G
Sbjct: 1014 CVCPPHTQGVKCEE--CEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGG 1071
Query: 394 LYCNETCSPGFYGEACQQICSC-------------QNGADCDSVTGKCTCAPGFKGIDCS 440
C++ CS G+ C C Q C TG C C G C+
Sbjct: 1072 RACDQ-CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCN 1130
Query: 441 TPCPLGTYGINCSSRCGCKNDAVCSPVDGSCT 472
C GT+ + + GC + CS + C+
Sbjct: 1131 -ECREGTFALRADNPLGC-SPCFCSGLSHLCS 1160
Score = 147 bits (370), Expect = 7e-35
Identities = 121/380 (31%), Positives = 163/380 (42%), Gaps = 69/380 (18%)
Query: 514 CTCAPGWRGEKCELPCQDGTYGLN------CAERCDC-SHADGCHPTTGHCRCLPGWSGV 566
C C G+ G CE C G Y ++ + C+C HA C+ C +GV
Sbjct: 709 CECPQGYTGTSCE-SCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGV 767
Query: 567 HCDSVCAEGRWG------PNCSLPCYC-------KNGASCSPDDG---ICE-CAPGFRGT 609
HC+ C G +G P PC C +C +DG +C+ CAPG+ G
Sbjct: 768 HCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 610 TCQRICSPGFYGHRC--SQTCPQCVHS-------SGPCHHITGLC-DCLPGFTGALCNEV 659
C+R C+ G+YG+ ++C C S +G C +TG C CL GA C E
Sbjct: 827 WCER-CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC-ER 884
Query: 660 CPSGRFG-----KNCAGICTC----TNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGP 710
C G +G KNC C C +++ C+ C C P G C Q C ++G
Sbjct: 885 CADGFYGDAVTAKNCRA-CECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGYYGL 942
Query: 711 NCIH---TCNCHNGAFCS---AYDGECKCTPGWTGLYCTQRCPLGFYGKD--CALICQCQ 762
+ H CNC S +G+C C PG G C RC GFY C C
Sbjct: 943 DSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRC-DRCAHGFYAYQDGSCTPCDCP 1001
Query: 763 NGAD-CDHISGQCTCRTGFMGRHCEQKCPSGTYGY----GCRQICDC-LNNST---CDHI 813
+ + CD +G+C C G CE+ C G +GY GC Q C+C L ST CD +
Sbjct: 1002 HTQNTCDPETGECVCPPHTQGVKCEE-CEDGHWGYDAEVGC-QACNCSLVGSTHHRCDVV 1059
Query: 814 TGTCYCSPGWKGARCDQAGV 833
TG C C + G CDQ +
Sbjct: 1060 TGHCQCKSKFGGRACDQCSL 1079
Score = 139 bits (349), Expect = 2e-32
Identities = 130/462 (28%), Positives = 179/462 (38%), Gaps = 98/462 (21%)
Query: 428 CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCP 487
C C G+ G C + C G Y ++ G +C P C+ H +C++
Sbjct: 709 CECPQGYTGTSCES-CLSGYYRVD-----GILFGGICQP------CECHGHAAECNVH-- 754
Query: 488 SGTWGFGCNLTCQCLNGGACNTLDGTCT-CAPGWRGEKCELPCQDGTYGLNCAERCDC-- 544
G + C A NT C C PG+ GE GT G +C + C C
Sbjct: 755 ------GVCIAC------AHNTTGVHCEQCLPGFYGEPSR-----GTPG-DC-QPCACPL 795
Query: 545 -----SHADGCHPTTGH---CR-CLPGWSGVHCDSVCAEGRWGP-----NCSLPCYCKNG 590
+ + CH G C C PG+SG C+ CA+G +G +PC C
Sbjct: 796 TIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER-CADGYYGNPTVPGESCVPCDCSGN 854
Query: 591 AS------CSPDDGIC-ECAPGFRGTTCQRICSPGFYGHRCS-QTCPQC-VHSSGP---- 637
C G C +C G C+R C+ GFYG + + C C H G
Sbjct: 855 VDPSEAGHCDSVTGECLKCLGNTDGAHCER-CADGFYGDAVTAKNCRACECHVKGSHSAV 913
Query: 638 CHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPI------DRSCQCY 691
CH TGLCDC P TG C++ C G +G + C N + + C C
Sbjct: 914 CHLETGLCDCKPNVTGQQCDQ-CLHGYYGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCV 972
Query: 692 PGWIGSDCSQPCPP--AHWGPNCIHTCNC-HNGAFCSAYDGECKCTPGWTGLYCTQRCPL 748
PG G C + A+ +C C+C H C GEC C P G+ C + C
Sbjct: 973 PGVAGKRCDRCAHGFYAYQDGSCT-PCDCPHTQNTCDPETGECVCPPHTQGVKC-EECED 1030
Query: 749 GFYGKDCALICQCQNGA-------DCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQI 801
G +G D + CQ N + CD ++G C C++ F GR C+Q C G +
Sbjct: 1031 GHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQ-CSLGYRDFPDCVP 1089
Query: 802 CDCLNNST-------------CDHITGTCYCSPGWKGARCDQ 830
CDC T C TG C C G +C++
Sbjct: 1090 CDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGPQCNE 1131
Score = 134 bits (338), Expect = 4e-31
Identities = 107/329 (32%), Positives = 143/329 (43%), Gaps = 63/329 (19%)
Query: 556 HCRCLPGWSGVHCDSVCAEGRW-------GPNCSLPCYCKNGASCSPDDGIC-ECAPGFR 607
HC C G++G C+S C G + G C PC C A+ G+C CA
Sbjct: 708 HCECPQGYTGTSCES-CLSGYYRVDGILFGGICQ-PCECHGHAAECNVHGVCIACAHNTT 765
Query: 608 GTTCQRICSPGFYGHRCSQT--------CPQCVHS---SGPCHHITG---LCD-CLPGFT 652
G C++ C PGFYG T CP + S S CH G +CD C PG++
Sbjct: 766 GVHCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYS 824
Query: 653 GALCNEVCPSGRF------GKNCAGICTCTNN------GTCNPIDRSC-QCYPGWIGSDC 699
GA C E C G + G++C C C+ N G C+ + C +C G+ C
Sbjct: 825 GAWC-ERCADGYYGNPTVPGESCVP-CDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHC 882
Query: 700 SQPCPPAHWG-----PNCIHTCNCH----NGAFCSAYDGECKCTPGWTGLYCTQRCPLGF 750
+ C +G NC C CH + A C G C C P TG C Q C G+
Sbjct: 883 ER-CADGFYGDAVTAKNC-RACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQ-CLHGY 939
Query: 751 YGKDCALICQCQNGADCDHIS------GQCTCRTGFMGRHCEQKCPSGTYGY--GCRQIC 802
YG D C+ N + +S GQC C G G+ C+ +C G Y Y G C
Sbjct: 940 YGLDSGHGCRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCD-RCAHGFYAYQDGSCTPC 998
Query: 803 DCLN-NSTCDHITGTCYCSPGWKGARCDQ 830
DC + +TCD TG C C P +G +C++
Sbjct: 999 DCPHTQNTCDPETGECVCPPHTQGVKCEE 1027
Score = 130 bits (327), Expect = 7e-30
Identities = 114/399 (28%), Positives = 145/399 (36%), Gaps = 71/399 (17%)
Query: 93 QCCPGFYESGEMCVPHCADKCVHGRCIAPN----TCQ-----------CEPGWGGTNCSS 137
QC PGFY P C IA N TC C PG+ G C
Sbjct: 771 QCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER 830
Query: 138 ACDGDHWGP----------HCTSRCQCKNGALCNPITGAC-HCAAGFRGWRCEDRCEQGT 186
DG + P C+ C+ +TG C C G CE RC G
Sbjct: 831 CADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCE-RCADGF 889
Query: 187 YGN-----DCHQRCQC----QNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQR 237
YG+ +C + C+C + A C TG C C P TG C D C G +G
Sbjct: 890 YGDAVTAKNC-RACECHVKGSHSAVCHLETGLCDCKPNVTGQQC-DQCLHGYYGLDSGHG 947
Query: 238 C-PCQ---NGGVCHHVT--GECSCPSGWMGTVCGQPCPEG--RFGKNCSQECQC-HNGGT 288
C PC G V T G+C C G G C + C G + C C H T
Sbjct: 948 CRPCNCSVAGSVSDGCTDEGQCHCVPGVAGKRCDR-CAHGFYAYQDGSCTPCDCPHTQNT 1006
Query: 289 CDAATGQCHCSPGYTGERCQDECPVGTYGV---LCAETCQCVNGGKCYH----VSGACLC 341
CD TG+C C P G +C +EC G +G + + C C G +H V+G C C
Sbjct: 1007 CDPETGECVCPPHTQGVKC-EECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQC 1065
Query: 342 EAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH-----------SCHPMSGECACKPG 390
++ F G C+ C G C C L T C +G C CK
Sbjct: 1066 KSKFGGRACDQ--CSLGYRDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKEN 1123
Query: 391 WSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCT 429
G CNE C G + C + C ++ C+
Sbjct: 1124 VFGPQCNE-CREGTFALRADNPLGC-SPCFCSGLSHLCS 1160
Score = 73.2 bits (178), Expect = 1e-12
Identities = 57/185 (30%), Positives = 74/185 (40%), Gaps = 45/185 (24%)
Query: 687 SCQCYPGWIGSDCSQPCPPAHWGP--------------NCIHTCNCHNGA-FCSAYDGEC 731
+C C PG +G C P H G C+ C+C+N + C G+C
Sbjct: 1361 NCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCV-PCSCNNHSDTCDPNTGKC 1419
Query: 732 -KCTPGWTGLYCTQRCPLGFYGK------DCALICQCQNGADC----------DHISGQC 774
C G +C C G+YGK DCAL C C + DH
Sbjct: 1420 LNCGDNTAGDHCDV-CTSGYYGKVTGSASDCAL-CACPHSPPASFSPTCVLEGDHDFRCD 1477
Query: 775 TCRTGFMGRHCEQKCPSGTYGY-----GCRQICDCLNNST----CDHITGTCYCSPGWKG 825
C G+ G+HCE +C S YG G Q CDC + + CD +G C C G G
Sbjct: 1478 ACLLGYEGKHCE-RCSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCDRTSGQCVCRLGASG 1536
Query: 826 ARCDQ 830
RCD+
Sbjct: 1537 LRCDE 1541
Score = 72.4 bits (176), Expect = 2e-12
Identities = 65/202 (32%), Positives = 84/202 (41%), Gaps = 47/202 (23%)
Query: 486 CPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNC-AERCDC 544
CP GT GF C CAPG+ K G L C C
Sbjct: 1364 CPPGTVGFSCQ------------------DCAPGYHRGKLPAGSDRGPRPLVAPCVPCSC 1405
Query: 545 S-HADGCHPTTGHC-RCLPGWSGVHCDSVCAEGRWGP------NCSLPCYCKNG--ASCS 594
+ H+D C P TG C C +G HCD VC G +G +C+L C C + AS S
Sbjct: 1406 NNHSDTCDPNTGKCLNCGDNTAGDHCD-VCTSGYYGKVTGSASDCAL-CACPHSPPASFS 1463
Query: 595 PD-------DGICE-CAPGFRGTTCQRICSPGFYGHRCSQ--TCPQC---VHSS--GPCH 639
P D C+ C G+ G C+R CS +YG+ + +C +C H S G C
Sbjct: 1464 PTCVLEGDHDFRCDACLLGYEGKHCER-CSSSYYGNPQTPGGSCQKCDCNPHGSVHGDCD 1522
Query: 640 HITGLCDCLPGFTGALCNEVCP 661
+G C C G +G C+E P
Sbjct: 1523 RTSGQCVCRLGASGLRCDECEP 1544
Score = 70.5 bits (171), Expect = 9e-12
Identities = 69/264 (26%), Positives = 93/264 (35%), Gaps = 82/264 (31%)
Query: 210 CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCP 269
C CPPG G C+D C PG H G+ S PC
Sbjct: 1362 CVCPPGTVGFSCQD-CAPGYH-------------------RGKLPAGSDRGPRPLVAPCV 1401
Query: 270 EGRFGKNCSQECQCHN-GGTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCAETCQCV 327
C C+N TCD TG+C +C G+ C D C G YG + C
Sbjct: 1402 P----------CSCNNHSDTCDPNTGKCLNCGDNTAGDHC-DVCTSGYYGKVTGSASDCA 1450
Query: 328 NGGKCYHVSGACLCEAGFAGERCEARLCP-EGLYGIKCDKRCPCHLENTHSCHPMSGECA 386
LC + + C EG + +CD A
Sbjct: 1451 ------------LCACPHSPPASFSPTCVLEGDHDFRCD--------------------A 1478
Query: 387 CKPGWSGLYCNETCSPGFYGE------ACQQICSCQ-NGA---DCDSVTGKCTCAPGFKG 436
C G+ G +C E CS +YG +CQ+ C C +G+ DCD +G+C C G G
Sbjct: 1479 CLLGYEGKHC-ERCSSSYYGNPQTPGGSCQK-CDCNPHGSVHGDCDRTSGQCVCRLGASG 1536
Query: 437 IDCSTPCP----LGTYGINCSSRC 456
+ C P + T ++C C
Sbjct: 1537 LRCDECEPRHILMETDCVSCDDEC 1560
Score = 67.0 bits (162), Expect = 1e-10
Identities = 59/212 (27%), Positives = 79/212 (37%), Gaps = 56/212 (26%)
Query: 600 CECAPGFRGTTCQRICSPGFYGHRC---SQTCPQ----------CVHSSGPCHHITGLC- 645
C C PG G +CQ C+PG++ + S P+ C + S C TG C
Sbjct: 1362 CVCPPGTVGFSCQD-CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 646 DCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPP 705
+C G C +VC SG +GK C C C PP
Sbjct: 1421 NCGDNTAGDHC-DVCTSGYYGKVTGSASDCA----------LCAC----------PHSPP 1459
Query: 706 AHWGPNCIHTCNCHNGAFCSAYDGECK-CTPGWTGLYCTQRCPLGFYGKDCALICQCQN- 763
A + P C+ + +D C C G+ G +C +RC +YG CQ
Sbjct: 1460 ASFSPTCVLEGD---------HDFRCDACLLGYEGKHC-ERCSSSYYGNPQTPGGSCQKC 1509
Query: 764 --------GADCDHISGQCTCRTGFMGRHCEQ 787
DCD SGQC CR G G C++
Sbjct: 1510 DCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE 1541
Score = 65.1 bits (157), Expect = 4e-10
Identities = 70/274 (25%), Positives = 98/274 (35%), Gaps = 59/274 (21%)
Query: 102 GEMCVPHC-ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH---WGPHCTSRCQCKNG 157
G MC+ + A C CQCE G +C+ C G H W P S +G
Sbjct: 267 GGMCICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVS-----SG 321
Query: 158 ALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGEC-RCPPGY 216
C AC+C ++ + Y ++ + N A G C C
Sbjct: 322 NTCE----ACNC---------HNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNT 368
Query: 217 TGAFCEDLCP----PGKHGPQCEQRCPCQNGGVCHHVTGECSC-PSGWMGTVCGQPCPEG 271
G CE P K P ++ PC+ C+C P G + +VC +
Sbjct: 369 MGINCETCIDGYYRPHKVSPYEDE--PCR----------PCNCDPVGSLSSVCIKD---- 412
Query: 272 RFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQC--VNG 329
HNG GQC C GYTGE+C D C +G +C C V
Sbjct: 413 ------DLHSDLHNG----KQPGQCPCKEGYTGEKC-DRCQLGYKDYPTCVSCGCNPVGS 461
Query: 330 GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIK 363
+G C+C+ G+ C+ C G Y +K
Sbjct: 462 ASDEPCTGPCVCKENVEGKACDR--CKPGFYNLK 493
Score = 65.1 bits (157), Expect = 4e-10
Identities = 59/205 (28%), Positives = 72/205 (35%), Gaps = 41/205 (20%)
Query: 124 CQCEPGWGGTNCSSACDGDHWG--PHCTSR-----------CQCKNGA-LCNPITGAC-H 168
C C PG G +C G H G P + R C C N + C+P TG C +
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCLN 1421
Query: 169 CAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPG 228
C G C D C G YG C C CP +F G
Sbjct: 1422 CGDNTAGDHC-DVCTSGYYGKVTGSASDC----------ALCACPHSPPASFSPTCVLEG 1470
Query: 229 KHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNG-- 286
H +C+ G C C S + G P G + C +C H
Sbjct: 1471 DHDFRCDACLLGYEGKHCER------CSSSYY----GNPQTPGGSCQKC--DCNPHGSVH 1518
Query: 287 GTCDAATGQCHCSPGYTGERCQDEC 311
G CD +GQC C G +G RC DEC
Sbjct: 1519 GDCDRTSGQCVCRLGASGLRC-DEC 1542
Score = 63.2 bits (152), Expect = 1e-09
Identities = 61/216 (28%), Positives = 76/216 (35%), Gaps = 68/216 (31%)
Query: 385 CACKPGWSGLYCNETCSPGFYGEACQQ--------------ICSCQNGAD-CDSVTGKC- 428
C C PG G C + C+PG++ CSC N +D CD TGKC
Sbjct: 1362 CVCPPGTVGFSCQD-CAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTCDPNTGKCL 1420
Query: 429 TCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCS-----PVDGSCTCKAGWHGVDCS 483
C G C C G YG S C A+C+ P S TC
Sbjct: 1421 NCGDNTAGDHCDV-CTSGYYGKVTGSASDC---ALCACPHSPPASFSPTCVL-------- 1468
Query: 484 IRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL-----NC 538
G F C+ C G+ G+ CE C YG
Sbjct: 1469 ----EGDHDFRCD------------------ACLLGYEGKHCER-CSSSYYGNPQTPGGS 1505
Query: 539 AERCDCS-----HADGCHPTTGHCRCLPGWSGVHCD 569
++CDC+ H D C T+G C C G SG+ CD
Sbjct: 1506 CQKCDCNPHGSVHGD-CDRTSGQCVCRLGASGLRCD 1540
Score = 60.8 bits (146), Expect = 7e-09
Identities = 69/258 (26%), Positives = 96/258 (37%), Gaps = 34/258 (13%)
Query: 209 ECRCPPGYTGAFCEDLCP--------PG--KHGPQCEQRCPCQNGGVCHHVTGECSCPSG 258
+C+C G C CP PG G CE C C N + +
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEA-CNCHNKAKDCYYDESVAKQKK 347
Query: 259 WMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQD-EC-PVGTY 316
+ T GQ G NC Q N TC + H Y E C+ C PVG+
Sbjct: 348 SLNTA-GQ-FRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSL 405
Query: 317 GVLCA--ETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLEN 374
+C + ++ GK G C C+ G+ GE+C+ C G C C+
Sbjct: 406 SSVCIKDDLHSDLHNGK---QPGQCPCKEGYTGEKCDR--CQLGYKDYPTCVSCGCNPVG 460
Query: 375 THSCHPMSGECACKPGWSGLYCNETCSPGFYG------EACQQICSCQNGAD-CDSVT-- 425
+ S P +G C CK G C + C PGFY C + C C +D C S++
Sbjct: 461 SASDEPCTGPCVCKENVEGKAC-DRCKPGFYNLKEKNPRGCSE-CFCFGVSDVCSSLSWP 518
Query: 426 -GKCTCAPGFKGIDCSTP 442
G+ G+ D +P
Sbjct: 519 VGQVNSMSGWLVTDLISP 536
Score = 60.1 bits (144), Expect = 1e-08
Identities = 66/272 (24%), Positives = 96/272 (35%), Gaps = 46/272 (16%)
Query: 585 CYCKNGASCSPDDGI-----CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCH 639
C C AS P D C+C G +C R C PG++ P V S C
Sbjct: 270 CICYGHASSCPWDETTKKLQCQCEHNTCGESCNRCC-PGYHQQPWR---PGTVSSGNTCE 325
Query: 640 HITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTC-----NPIDRSCQ-CYPG 693
C+C +E + N AG G C N + +C+ C G
Sbjct: 326 ----ACNCHNKAKDCYYDESVAKQKKSLNTAG--QFRGGGVCINCLQNTMGINCETCIDG 379
Query: 694 W-----IGSDCSQPCPPAHWGPNCIHTCNC-----HNGAFCSAYDGECKCTPGWTGLYCT 743
+ + +PC P + P + C H+ G+C C G+TG C
Sbjct: 380 YYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKC- 438
Query: 744 QRCPLGFYGKDCALICQCQ--NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGY----- 796
RC LG+ + C C A + +G C C+ G+ C+ +C G Y
Sbjct: 439 DRCQLGYKDYPTCVSCGCNPVGSASDEPCTGPCVCKENVEGKACD-RCKPGFYNLKEKNP 497
Query: 797 -GCRQICDCLN-NSTCDHIT---GTCYCSPGW 823
GC + C C + C ++ G GW
Sbjct: 498 RGCSE-CFCFGVSDVCSSLSWPVGQVNSMSGW 528
Score = 58.2 bits (139), Expect = 4e-08
Identities = 74/297 (24%), Positives = 97/297 (32%), Gaps = 102/297 (34%)
Query: 384 ECACKPGWSGLYCNETCSPGFY-----------GEACQQICSCQNGA-DC---DSVTGK- 427
+C C+ G CN C PG++ G C+ C+C N A DC +SV +
Sbjct: 289 QCQCEHNTCGESCNRCC-PGYHQQPWRPGTVSSGNTCEA-CNCHNKAKDCYYDESVAKQK 346
Query: 428 --CTCAPGFKGIDCSTPCPLGTYGINCSS---------RCGCKNDAVCSPVDGSCTCKAG 476
A F+G C T GINC + + D C P C C
Sbjct: 347 KSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRP----CNCD-- 400
Query: 477 WHGVDCSIRCPSGTWGFGC---NLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGT 533
P G+ C +L NG G C C G+ GEKC+
Sbjct: 401 ----------PVGSLSSVCIKDDLHSDLHNGKQ----PGQCPCKEGYTGEKCD------- 439
Query: 534 YGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC 593
RC + D +PT C C P S AS
Sbjct: 440 -------RCQLGYKD--YPTCVSCGCNPVGS--------------------------ASD 464
Query: 594 SPDDGICECAPGFRGTTCQRICSPGFYG--HRCSQTCPQCVHSSGPCHHITGLCDCL 648
P G C C G C R C PGFY + + C +C C ++ +C L
Sbjct: 465 EPCTGPCVCKENVEGKACDR-CKPGFYNLKEKNPRGCSECF-----CFGVSDVCSSL 515
Score = 54.7 bits (130), Expect = 5e-07
Identities = 40/132 (30%), Positives = 55/132 (41%), Gaps = 26/132 (19%)
Query: 731 CKCTPGWTGLYCTQRCPLGFYGKDCALI------CQCQNGADCDHISGQC-TCRTGFMGR 783
C+C G+TG C + C G+Y D L C+C A ++ G C C G
Sbjct: 709 CECPQGYTGTSC-ESCLSGYYRVDGILFGGICQPCECHGHAAECNVHGVCIACAHNTTGV 767
Query: 784 HCEQKCPSGTYGYGCR------QICDCLNNSTCDHITGTCY-----------CSPGWKGA 826
HCEQ C G YG R Q C C ++ + TC+ C+PG+ GA
Sbjct: 768 HCEQ-CLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 827 RCDQAGVIIVGN 838
C++ GN
Sbjct: 827 WCERCADGYYGN 838
Score = 43.1 bits (100), Expect = 0.001
Identities = 44/157 (28%), Positives = 56/157 (35%), Gaps = 46/157 (29%)
Query: 105 CVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCK-NGALCNPI 163
CVP + H PNT +C NC GDH CTS K G+ +
Sbjct: 1400 CVPCSCNN--HSDTCDPNTGKC------LNCGDNTAGDHCDV-CTSGYYGKVTGSASDCA 1450
Query: 164 TGACH-----------------------CAAGFRGWRCEDRCEQGTYGN------DCHQR 194
AC C G+ G CE RC YGN C Q+
Sbjct: 1451 LCACPHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCE-RCSSSYYGNPQTPGGSC-QK 1508
Query: 195 CQCQNGAT----CDHVTGECRCPPGYTGAFCEDLCPP 227
C C + CD +G+C C G +G C++ C P
Sbjct: 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDE-CEP 1544
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 172 bits (436), Expect = 2e-42
Identities = 143/424 (33%), Positives = 167/424 (39%), Gaps = 90/424 (21%)
Query: 238 CPCQNGGV----CHHVTGECSCPSGWMGTVCGQPCPEGR--FGKNCSQECQCHNGGT--- 288
C C G C+ G+C C G +G C C G FG Q CQC + G
Sbjct: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGALSS 841
Query: 289 -CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG--GKCYHVSGACL-CEAG 344
C+ +GQC C G G RC D C G +G C C NG +C +GACL C
Sbjct: 842 LCEKTSGQCLCRTGAFGLRC-DRCQRGQWGFPSCRPCVC-NGHADECNTHTGACLGCRDH 899
Query: 345 FAGERCEARLC-----PEGLYGIKCDKRCPC------HLENTHSCHPMSGE----CACKP 389
GE CE + P YG +C + CPC SCH C C+
Sbjct: 900 TGGEHCERCIAGFHGDPRLPYGGQC-RPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
Query: 390 GWSGLYCNETCSPGFYGEACQ-----QICSCQNGAD------CDSVTGKCT--------- 429
G++GL C E C+PG +G+ + Q+C C D CD TG+C
Sbjct: 959 GYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
Query: 430 ----CAPGFKGIDCSTPCP------LGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHG 479
C PGF G C LGT C S C C P G C C G
Sbjct: 1018 HCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH----CDPSSGQCPCLPNVQG 1073
Query: 480 VDCSIRCPSGTW----GFGCNLTCQC----LNGGACNTLDGTCTCAPGWRGEKCELPCQD 531
C RC W G GC C C G CN G C C G+ G C CQ+
Sbjct: 1074 PSCD-RCAPNFWNLTSGHGCQ-PCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQE 1130
Query: 532 ---GTYGLNCAERCDCSH----ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWG--PNCS 582
G GL C CDC CH TGHC C PG SGV CD CA G G P C
Sbjct: 1131 LHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSGIFPACH 1188
Query: 583 LPCY 586
PC+
Sbjct: 1189 -PCH 1191
Score = 165 bits (418), Expect = 2e-40
Identities = 129/405 (31%), Positives = 158/405 (39%), Gaps = 81/405 (20%)
Query: 497 LTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCA--ERCDCSHADG- 549
L CQC G+ CN G C C PG G +C+L C G YG + C CSH
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGAL 839
Query: 550 ---CHPTTGHCRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGIC-ECA 603
C T+G C C G G+ CD C G+WG P+C PC C A C+ G C C
Sbjct: 840 SSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCR-PCVCNGHADECNTHTGACLGCR 897
Query: 604 PGFRGTTCQRICSPGF-------YGHRCSQTCPQCVHSSGPCHHITG-----------LC 645
G C+R C GF YG +C + CP C G H +C
Sbjct: 898 DHTGGEHCER-CIAGFHGDPRLPYGGQC-RPCP-CPEGPGSQRHFATSCHQDEYSQQIVC 954
Query: 646 DCLPGFTGALCNEVCPSGRFGKNC-----AGICTCTNN------GTCNPIDRSC-QCYPG 693
C G+TG C E C G FG +C C+ N C+P C +C
Sbjct: 955 HCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHH 1013
Query: 694 WIGSDCSQPCPPAHWGP---NCIHTCNCH------------NGAFCSAYDGECKCTPGWT 738
G C+ C P G H C C+ + C G+C C P
Sbjct: 1014 TEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQ 1072
Query: 739 GLYCTQRCPLGFYG-------KDCALICQCQNGADCDHISGQCTCRTGFMGRHCE--QKC 789
G C RC F+ + CA G C+ +GQC CR GF GR C Q+
Sbjct: 1073 GPSC-DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQEL 1131
Query: 790 PSGTYGYGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
G G C CDC ++ C TG C C PG G RCDQ
Sbjct: 1132 HWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
Score = 150 bits (380), Expect = 5e-36
Identities = 137/447 (30%), Positives = 181/447 (40%), Gaps = 95/447 (21%)
Query: 93 QCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH-WGPHCTSR 151
QC P S E C PH G+C+ C+PG G C G + +GP
Sbjct: 784 QCNPQGSLSSE-CNPH------GGQCL------CKPGVVGRRCDLCAPGYYGFGPTGCQA 830
Query: 152 CQCKN----GALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGA-TCDHV 206
CQC + +LC +G C C G G RC DRC++G +G + C C A C+
Sbjct: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRC-DRCQRGQWGFPSCRPCVCNGHADECNTH 889
Query: 207 TGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQ 266
TG C +TG + C G HG + R P GG C C CP G
Sbjct: 890 TGACLGCRDHTGGEHCERCIAGFHG---DPRLP--YGGQCR----PCPCPEG-------- 932
Query: 267 PCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQDECPVGTYGVLC---- 320
P + F +C Q D + Q CHC GYTG RC + C G +G
Sbjct: 933 PGSQRHFATSCHQ----------DEYSQQIVCHCRAGYTGLRC-EACAPGHFGDPSRPGG 981
Query: 321 -AETCQC------VNGGKCYHVSGACL-CEAGFAGERCEARLCPEGLYGIKCDK---RCP 369
+ C+C ++ C +G CL C G C C G +G + RC
Sbjct: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAH--CKPGFHGQAARQSCHRCT 1039
Query: 370 CHLENTH----------SCHPMSGECACKPGWSGLYCNETCSPGFY----GEACQQICSC 415
C+L T+ C P SG+C C P G C + C+P F+ G CQ C+C
Sbjct: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSC-DRCAPNFWNLTSGHGCQP-CAC 1097
Query: 416 Q----NGADCDSVTGKCTCAPGFKGIDCSTPCPL--GTYGINCSSRCGCKNDAV----CS 465
G C+ TG+C C GF G CS L G G+ C + C C + + C
Sbjct: 1098 HPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHA-CDCDSRGIDTPQCH 1156
Query: 466 PVDGSCTCKAGWHGVDCSIRCPSGTWG 492
G C+C+ G GV C +C G G
Sbjct: 1157 RFTGHCSCRPGVSGVRCD-QCARGFSG 1182
Score = 114 bits (285), Expect = 5e-25
Identities = 101/330 (30%), Positives = 125/330 (37%), Gaps = 78/330 (23%)
Query: 104 MCVPHCADKC-VH-GRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCN 161
+C H AD+C H G C+ C GG +C G H P QC+ C
Sbjct: 878 VCNGH-ADECNTHTGACLG-----CRDHTGGEHCERCIAGFHGDPRLPYGGQCRP-CPCP 930
Query: 162 PITGA------------------CHCAAGFRGWRCEDRCEQGTYGNDCH-----QRCQCQ 198
G+ CHC AG+ G RCE C G +G+ Q C+C
Sbjct: 931 EGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCE-ACAPGHFGDPSRPGGRCQLCECS 989
Query: 199 NGA------TCDHVTGEC-RCPPGYTGAFCEDLCPPGKHGPQCEQ---RCPCQNGGV--- 245
CD TG+C RC G C C PG HG Q RC C G
Sbjct: 990 GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQ 1048
Query: 246 ---------CHHVTGECSCPSGWMGTVCGQPCPEG---RFGKNCSQECQCH----NGGTC 289
C +G+C C G C + P G C Q C CH G TC
Sbjct: 1049 QCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC-QPCACHPSRARGPTC 1107
Query: 290 DAATGQCHCSPGYTGERCQD--ECPVGTYGVLCAETCQCVNGG----KCYHVSGACLCEA 343
+ TGQCHC G+ G C + E G G+ C C C + G +C+ +G C C
Sbjct: 1108 NEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRP 1166
Query: 344 GFAGERCEARLCPEGLYGI--KCDKRCPCH 371
G +G RC+ C G GI C PCH
Sbjct: 1167 GVSGVRCDQ--CARGFSGIFPACH---PCH 1191
Score = 100 bits (250), Expect = 6e-21
Identities = 81/274 (29%), Positives = 98/274 (35%), Gaps = 55/274 (20%)
Query: 93 QCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGP------ 146
QC P G H A C C C G+ G C AC H+G
Sbjct: 923 QCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRC-EACAPGHFGDPSRPGG 981
Query: 147 -----HCTSRCQCKNGALCNPITGAC-------------HCAAGFRGWRCEDRCEQ---- 184
C+ + C+P TG C HC GF G C +
Sbjct: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCN 1041
Query: 185 --GTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCEDLCPPG----KHGPQCEQRC 238
GT C QC CD +G+C C P G C D C P G C Q C
Sbjct: 1042 LLGTNPQQCPSPDQCH----CDPSSGQCPCLPNVQGPSC-DRCAPNFWNLTSGHGC-QPC 1095
Query: 239 PCQ----NGGVCHHVTGECSCPSGWMGTVCGQPCPE---GRFGKNCSQECQCHNGG---- 287
C G C+ TG+C C +G+ G C + C E G G C C C + G
Sbjct: 1096 ACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE-CQELHWGDPGLQC-HACDCDSRGIDTP 1153
Query: 288 TCDAATGQCHCSPGYTGERCQDECPVGTYGVLCA 321
C TG C C PG +G RC D+C G G+ A
Sbjct: 1154 QCHRFTGHCSCRPGVSGVRC-DQCARGFSGIFPA 1186
Score = 87.8 bits (216), Expect = 5e-17
Identities = 77/255 (30%), Positives = 99/255 (38%), Gaps = 70/255 (27%)
Query: 335 VSGACLCEAGFAGERCEA----------RLCPEGLYGIKCDKRCPCHLENTHSCH----- 379
V GAC+C+ G CE R +G + C ++C CH +THSCH
Sbjct: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG-HSHAC-RKCECH-GHTHSCHFDMAV 362
Query: 380 ------PMSGEC-ACKPGWSGLYCNETCSPGFYGEACQQI--------CSC-----QNGA 419
G C C+ +G +C E C P FY + + + C C Q+G
Sbjct: 363 YLASGNVSGGVCDGCQHNTAGRHC-ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG 421
Query: 420 DCDS--------VTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN----------- 460
CDS V+G+C C G C C G +G++ S R GC+
Sbjct: 422 RCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPG 480
Query: 461 DAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNGGA----CNTLD 511
C P GSC CK G C RC G WG GC C C GGA C+
Sbjct: 481 STPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGLSHDLLGCR-PCDCDVGGALDPQCDEGT 538
Query: 512 GTCTCAPGWRGEKCE 526
G C C G +CE
Sbjct: 539 GQCHCRQHMVGRRCE 553
Score = 86.3 bits (212), Expect = 2e-16
Identities = 82/292 (28%), Positives = 108/292 (36%), Gaps = 52/292 (17%)
Query: 88 YRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH---W 144
Y S+C P P A+ VHG CI C+ G NC D W
Sbjct: 286 YGHASECAPA------PGAPAHAEGMVHGACI------CKHNTRGLNCEQCQDFYRDLPW 333
Query: 145 GP------HCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ 198
P H +C+C A + A+G D C+ T G C C+
Sbjct: 334 RPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCEL---CR 390
Query: 199 NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSG 258
D T + R P C+ + G Q RC + V+G+C C
Sbjct: 391 PFFYRDP-TKDLRDPAVCRSCDCDPM------GSQDGGRCDSHDDPALGLVSGQCRCKEH 443
Query: 259 WMGTVCGQPCPEGRFGKNCS-----QECQCHNGGT------CDAATGQCHCSPGYTGERC 307
+GT C Q C +G FG + S + CQC+ GT CD +G C+C TG C
Sbjct: 444 VVGTRC-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
Query: 308 QDECPVGTYGV----LCAETCQCVNGG----KCYHVSGACLCEAGFAGERCE 351
D C G +G+ L C C GG +C +G C C G RCE
Sbjct: 503 -DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
Score = 73.6 bits (179), Expect = 1e-12
Identities = 74/292 (25%), Positives = 104/292 (35%), Gaps = 66/292 (22%)
Query: 585 CYCKNGAS-CSPDDGI-----------CECAPGFRGTTCQRICS--------PGFYGHRC 624
C+C AS C+P G C C RG C++ P GH
Sbjct: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
Query: 625 SQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTC------TNN 678
+ +C + CH + +G +C+ C G++C +C T +
Sbjct: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG-CQHNTAGRHCE-LCRPFFYRDPTKD 400
Query: 679 GTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
+ RSC C P G C+ H+ G+C+C
Sbjct: 401 LRDPAVCRSCDCDP---------------MGSQDGGRCDSHDDPALGLVSGQCRCKEHVV 445
Query: 739 GLYCTQRCPLGFYGKDCA-----LICQCQ------NGADCDHISGQCTCRTGFMGRHCEQ 787
G C Q+C GF+G + CQC CD SG C C+ GR C+
Sbjct: 446 GTRC-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD- 503
Query: 788 KCPSGTYGY-----GCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
+C G +G GCR CDC + CD TG C+C G RC+Q
Sbjct: 504 RCLPGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ 554
Score = 73.6 bits (179), Expect = 1e-12
Identities = 55/177 (31%), Positives = 68/177 (38%), Gaps = 34/177 (19%)
Query: 92 SQCCPGFYESGEMCVPHCADKCVHG----RCIAPNTCQCEPGWGGTNC--------SSAC 139
+ C PGF+ H + G +C +P+ C C+P G C C
Sbjct: 1020 AHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRC 1079
Query: 140 DGDHWG---PHCTSRCQCK----NGALCNPITGACHCAAGFRGWRCEDRCEQ---GTYGN 189
+ W H C C G CN TG CHC AGF G C + C++ G G
Sbjct: 1080 APNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE-CQELHWGDPGL 1138
Query: 190 DCHQRCQCQNGA----TCDHVTGECRCPPGYTGAFCEDLCPPGKHG--PQCEQRCPC 240
CH C C + C TG C C PG +G C D C G G P C PC
Sbjct: 1139 QCH-ACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRC-DQCARGFSGIFPACH---PC 1190
Score = 70.1 bits (170), Expect = 1e-11
Identities = 81/305 (26%), Positives = 99/305 (32%), Gaps = 81/305 (26%)
Query: 512 GTCTCAPGWRGEKCELPCQDGTYGL----------NCAERCDC-SHADGCHPTTGHCRCL 560
G C C RG CE CQD L + +C+C H CH
Sbjct: 308 GACICKHNTRGLNCE-QCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLAS 366
Query: 561 PGWSGVHCDSVCAEGRWGPNCSL--PCYCKNGASCSPDDGICECAPGFRGTTCQRICSPG 618
SG CD C G +C L P + ++ D +C R C + S
Sbjct: 367 GNVSGGVCDG-CQHNTAGRHCELCRPFFYRDPTKDLRDPAVC------RSCDCDPMGSQD 419
Query: 619 FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNN 678
G RC H ++G C C G C + C G FG + + C
Sbjct: 420 --GGRCDS------HDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGC--- 467
Query: 679 GTCNPIDRSCQC-----YPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKC 733
R CQC PG S PC P G C C
Sbjct: 468 -------RRCQCNARGTVPG------STPCDPN---------------------SGSCYC 493
Query: 734 TPGWTGLYCTQRCPLGFYGKDCALI----CQCQNGA----DCDHISGQCTCRTGFMGRHC 785
TG C RC G +G L+ C C G CD +GQC CR +GR C
Sbjct: 494 KRLVTGRGC-DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
Query: 786 EQKCP 790
EQ P
Sbjct: 553 EQVQP 557
Score = 68.2 bits (165), Expect = 4e-11
Identities = 72/285 (25%), Positives = 96/285 (33%), Gaps = 85/285 (29%)
Query: 230 HGPQCEQR--CPCQNGGVCHHVTGECSCPSGWMGTVCGQ-----------PCPEGRFGKN 276
H +C P G+ H G C C G C Q P +G +
Sbjct: 288 HASECAPAPGAPAHAEGMVH---GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH--SH 342
Query: 277 CSQECQCHNGGTCDAATGQCH-------CSPGYTGERCQDECPVGTYGVLC--------- 320
++C+CH T CH S +G C D C T G C
Sbjct: 343 ACRKCECHGH------THSCHFDMAVYLASGNVSGGVC-DGCQHNTAGRHCELCRPFFYR 395
Query: 321 -----------AETCQC-----VNGGKCYH--------VSGACLCEAGFAGERCEARLCP 356
+C C +GG+C VSG C C+ G RC+ C
Sbjct: 396 DPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ--CR 453
Query: 357 EGLYGIKCD-----KRCPCHLENT----HSCHPMSGECACKPGWSGLYCNETCSPGFYGE 407
+G +G+ +RC C+ T C P SG C CK +G C+ C PG +G
Sbjct: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGL 512
Query: 408 ACQQI----CSCQNGA----DCDSVTGKCTCAPGFKGIDCSTPCP 444
+ + C C G CD TG+C C G C P
Sbjct: 513 SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 163 bits (413), Expect = 8e-40
Identities = 130/398 (32%), Positives = 163/398 (40%), Gaps = 76/398 (19%)
Query: 243 GGVCHHVTGECSCPSGWMGTVCGQPCPEGRF--GKNCSQECQCHNGGT----CDAATGQC 296
G C + G+C C +G C + C G + G + C CH G+ CD TGQC
Sbjct: 778 GSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQC 836
Query: 297 HCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGK-CYHVSGACLCEAGFA-GERCEARL 354
C +G RC D C G +G C C + C +G+C GF G CE
Sbjct: 837 PCHGEVSGRRC-DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCER-- 893
Query: 355 CPEGLYGIKCD----KRCPCHLENT------HSCHPMSGE----CACKPGWSGLYCNETC 400
C +G YG + C C + + HSC+ C C G++G C E C
Sbjct: 894 CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-C 952
Query: 401 SPGFYGE-----ACQQICSCQNGAD------CDSVTGKCT-CAPGFKGIDCSTPCPLGTY 448
S GFYG A Q C+C N D C VTG+C C +G +C C G Y
Sbjct: 953 STGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQL-CKPGHY 1011
Query: 449 GINCSS---RCGCKNDAV-------------CSPVDGSCTCKAGWHGVDCSIRCPSGTW- 491
G + RC C V C PV G+C C G+ C RC G W
Sbjct: 1012 GSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACD-RCADGYWN 1070
Query: 492 ---GFGCNLTCQC----LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYG---LNCAER 541
G GC +C C C+ L G C C G+ G++C CQ+ YG C
Sbjct: 1071 LVPGRGCQ-SCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENYYGDPPGRCIP- 1127
Query: 542 CDCSHADG----CHPTTGHCRCLPGWSGVHCDSVCAEG 575
CDC+ A C P TG CRC G SG CD CA G
Sbjct: 1128 CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR-CARG 1164
Score = 161 bits (407), Expect = 4e-39
Identities = 128/393 (32%), Positives = 166/393 (42%), Gaps = 76/393 (19%)
Query: 504 GGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL--NCAERCDCSHADG-----CHPTTGH 556
G +C+ L G C C P G C+ C G+Y L + C C H G C TG
Sbjct: 778 GSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHC-HPQGSKDTVCDQVTGQ 835
Query: 557 CRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGICECAPGFR-GTTCQR 613
C C SG CD C G +G P+C PC C A C P+ G C GF G C+R
Sbjct: 836 CPCHGEVSGRRCDR-CLAGYFGFPSCH-PCPCNRFAELCDPETGSCFNCGGFTTGRNCER 893
Query: 614 ICSPGFYGHRCS-QTCPQCVHSSGP---------CHHITG----LCDCLPGFTGALCNEV 659
C G+YG+ S Q C C+ P C+ +C+CL G+TG C E
Sbjct: 894 -CIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE- 951
Query: 660 CPSGRFGK-NCAGI----CTCTNN------GTCNPIDRSC-QCYPGWIGSDCSQPCPPAH 707
C +G +G +G C C NN +C+ + C +C G++C Q C P H
Sbjct: 952 CSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC-QLCKPGH 1010
Query: 708 WGPNCIHTC---NCH-------------NGAFCSAYDGECKCTPGWTGLYCTQRCPLGFY 751
+G TC +CH C G C C P TGL C RC G++
Sbjct: 1011 YGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC-DRCADGYW 1069
Query: 752 ----GKDCALICQCQ----NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG--YGCRQI 801
G+ C C C + CD ++GQC C+ G+ G+ C + C YG G
Sbjct: 1070 NLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYGDPPGRCIP 1127
Query: 802 CDCLNNST----CDHITGTCYCSPGWKGARCDQ 830
CDC T CD TG C C G G RCD+
Sbjct: 1128 CDCNRAGTQKPICDPDTGMCRCREGVSGQRCDR 1160
Score = 151 bits (381), Expect = 4e-36
Identities = 123/407 (30%), Positives = 161/407 (39%), Gaps = 76/407 (18%)
Query: 148 CTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYG------NDCHQRCQCQNGA 201
C Q G+ C+ + G C C G RC DRC G+Y + CH Q
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVG-RCCDRCSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQN-GGVCHHVTGEC-SCPSG 258
CD VTG+C C +G C D C G G P C CPC +C TG C +C
Sbjct: 828 VCDQVTGQCPCHGEVSGRRC-DRCLAGYFGFPSCHP-CPCNRFAELCDPETGSCFNCGGF 885
Query: 259 WMGTVCGQPCPEGRFGKNCS----QECQCHNGGTCD------------AATGQCHCSPGY 302
G C + C +G +G S + C C + + + ++ C+C GY
Sbjct: 886 TTGRNC-ERCIDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
Query: 303 TGERCQDECPVGTYG-----VLCAETCQCVNG------GKCYHVSGACL-CEAGFAGERC 350
TG +C EC G YG + C C N C V+G CL C G C
Sbjct: 945 TGTQC-GECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANC 1003
Query: 351 EARLCPEGLYGIKCD---KRCPCHLENTHS-----------CHPMSGECACKPGWSGLYC 396
+ LC G YG + +RC CH C P++G C C P +GL C
Sbjct: 1004 Q--LCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLAC 1061
Query: 397 NETCSPGFY----GEACQQICSC----QNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTY 448
+ C+ G++ G CQ C C + CD +TG+C C G+ G CS C Y
Sbjct: 1062 -DRCADGYWNLVPGRGCQS-CDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCS-ECQENYY 1118
Query: 449 G------INCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSG 489
G I C +C P G C C+ G G C RC G
Sbjct: 1119 GDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCD-RCARG 1164
Score = 133 bits (334), Expect = 1e-30
Identities = 113/380 (29%), Positives = 143/380 (37%), Gaps = 73/380 (19%)
Query: 124 CQCEPGWGGTNCSSACDGDH-WGPHCTSRCQC----KNGALCNPITGACHCAAGFRGWRC 178
CQC+P G C G + G H C C +C+ +TG C C G RC
Sbjct: 788 CQCKPLVVGRCCDRCSTGSYDLGHHGCHPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRC 847
Query: 179 EDRCEQGTYGNDCHQRCQCQNGA-TCDHVTGEC-RCPPGYTGAFCEDLCPPGKHG-PQCE 235
DRC G +G C C A CD TG C C TG CE C G +G P
Sbjct: 848 -DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFTTGRNCE-RCIDGYYGNPSSG 905
Query: 236 QRC--------PCQNGGVCHHVTGE-------CSCPSGWMGTVCGQPCPEGRFGK----- 275
Q C P N H C+C G+ GT CG+ C G +G
Sbjct: 906 QPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-CSTGFYGNPRISG 964
Query: 276 NCSQECQCHNG------GTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCAETC---- 324
Q C C+N +C TG+C C G CQ C G YG +TC
Sbjct: 965 APCQPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ-LCKPGHYGSALNQTCRRCS 1023
Query: 325 ---------QCVNGG---KCYHVSGACLCEAGFAGERCEARLCPEGLYGI-------KCD 365
+C GG C V+GAC C G C+ C +G + + CD
Sbjct: 1024 CHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR--CADGYWNLVPGRGCQSCD 1081
Query: 366 KRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQI--CSCQNGAD--- 420
C + C ++G+C CK G+ G C+E C +YG+ + C C
Sbjct: 1082 --CDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE-CQENYYGDPPGRCIPCDCNRAGTQKP 1138
Query: 421 -CDSVTGKCTCAPGFKGIDC 439
CD TG C C G G C
Sbjct: 1139 ICDPDTGMCRCREGVSGQRC 1158
Score = 112 bits (280), Expect = 2e-24
Identities = 101/331 (30%), Positives = 126/331 (38%), Gaps = 71/331 (21%)
Query: 82 HGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWG---GTNCSSA 138
HGE + RR +C G++ C P ++ P T C G G NC
Sbjct: 839 HGEVSG-RRCDRCLAGYF-GFPSCHPCPCNR--FAELCDPETGSCFNCGGFTTGRNCERC 894
Query: 139 CDGDHWGPHCTSRCQ---CKNGALCNPITG------------ACHCAAGFRGWRCEDRCE 183
DG + P C+ C + N C+C G+ G +C + C
Sbjct: 895 IDGYYGNPSSGQPCRPCLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGYTGTQCGE-CS 953
Query: 184 QGTYGND------CHQRCQCQNGA------TCDHVTGEC-RCPPGYTGAFCEDLCPPGKH 230
G YGN C Q C C N +C VTGEC RC GA C+ LC PG +
Sbjct: 954 TGFYGNPRISGAPC-QPCACNNNIDVTDPESCSRVTGECLRCLHNTQGANCQ-LCKPGHY 1011
Query: 231 GPQCEQ---RCPCQNGGV-------------CHHVTGECSCPSGWMGTVCGQPCPEGRF- 273
G Q RC C GV C VTG C C G C + C +G +
Sbjct: 1012 GSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPCLPNVTGLACDR-CADGYWN 1070
Query: 274 ---GKNCSQECQCH----NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAE--TC 324
G+ C Q C C CD TGQC C GY G+RC EC YG C
Sbjct: 1071 LVPGRGC-QSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRC-SECQENYYGDPPGRCIPC 1128
Query: 325 QCVNGGK----CYHVSGACLCEAGFAGERCE 351
C G C +G C C G +G+RC+
Sbjct: 1129 DCNRAGTQKPICDPDTGMCRCREGVSGQRCD 1159
Score = 77.8 bits (190), Expect = 5e-14
Identities = 76/283 (26%), Positives = 95/283 (33%), Gaps = 75/283 (26%)
Query: 92 SQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACD---GDHWGPHC 148
S+C P G++ P VHG+C+ C+ G NC D W P
Sbjct: 272 SECRPMQKMRGDVFSP---PGMVHGQCV------CQHNTDGPNCERCKDFFQDAPWRPAA 322
Query: 149 TSRCQCKNGALCNPITGACH-------CAAGFRGWRCEDRCEQGTYGNDCHQ-------- 193
+ CN + CH + G G CED C+ T G C +
Sbjct: 323 DLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCDRCRPLFYRD 381
Query: 194 ------------RCQCQ-----NGATC--------DHVTGECRCPPGYTGAFCEDLCPPG 228
C+C +G C V G+C C GA C D C P
Sbjct: 382 PLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKC-DQCKPN 440
Query: 229 KHG-----PQCEQRCPCQNGG-----VCHHVTGECSCPSGWMGTVCGQPCPEGRFG---- 274
+G P Q C C G C TG+C C S G C + C G +G
Sbjct: 441 HYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EECTVGYWGLGNH 499
Query: 275 -KNCSQECQCHNGGT----CDAATGQCHCSPGYTGERCQDECP 312
CS C C GG C GQC C P TG C + P
Sbjct: 500 LHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
Score = 75.1 bits (183), Expect = 4e-13
Identities = 71/271 (26%), Positives = 96/271 (35%), Gaps = 60/271 (22%)
Query: 294 GQCHCSPGYTG---ERCQDEC------PVGTYGVLCAETCQC-VNGGKCYHVSGACLCEA 343
GQC C G ERC+D P +C C + +C+ L
Sbjct: 293 GQCVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASG 352
Query: 344 GFAGERCEARLCPEGLYGIKCDKRCPCH-------LENTHSCHPMSGECACKPGWSGLYC 396
G +G CE C G CD+ P + + ++C P C C P
Sbjct: 353 GLSGGVCED--CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIP----CECDP------- 399
Query: 397 NETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRC 456
+ T S G IC + SV G+C C +G C C YG++ +
Sbjct: 400 DGTISGG--------ICVSHSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPL 450
Query: 457 GCKNDAVCSPVD-----------GSCTCKAGWHGVDCSIRCPSGTWGFGCNL----TCQC 501
GC+ C+P+ G C C + G C C G WG G +L C C
Sbjct: 451 GCQ-PCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE-ECTVGYWGLGNHLHGCSPCDC 508
Query: 502 LNGGA----CNTLDGTCTCAPGWRGEKCELP 528
GGA C+ +G C C P G C P
Sbjct: 509 DIGGAYSNVCSPKNGQCECRPHVTGRSCSEP 539
Score = 73.6 bits (179), Expect = 1e-12
Identities = 79/361 (21%), Positives = 128/361 (35%), Gaps = 65/361 (18%)
Query: 70 TRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAP-NTCQCEP 128
T R+++ + G+ + RR++ +Y + + V G C + +C P
Sbjct: 224 TNLRINFTKLHTLGDALLGRRQNDSLDKYYYA-------LYEMIVRGSCFCNGHASECRP 276
Query: 129 GWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYG 188
GD + P QC +C T +C RC+D + +
Sbjct: 277 -------MQKMRGDVFSPPGMVHGQC----VCQHNTDGPNCE------RCKDFFQDAPWR 319
Query: 189 NDCHQRCQCQNGATCDHVTGECR-------CPPGYTGAFCEDLCPPGKHGPQCEQRCPCQ 241
+ +C+ + C G +G CED C G C++ P
Sbjct: 320 PAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCDRCRPLF 378
Query: 242 NGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPG 301
++ +C PC G C H+ + GQC C
Sbjct: 379 YRDPLKTISDPYACI----------PCECDPDGTISGGICVSHSDPALGSVAGQCLCKEN 428
Query: 302 YTGERCQDECPVGTYGV-----LCAETCQCVNGGK-----CYHVSGACLCEAGFAGERCE 351
G +C D+C YG+ L + C C G C +G CLC + G CE
Sbjct: 429 VEGAKC-DQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCE 487
Query: 352 ARLCPEGLYGIK-----CDKRCPCHLENTHS--CHPMSGECACKPGWSGLYCNETCSPGF 404
C G +G+ C C C + +S C P +G+C C+P +G C+E +PG+
Sbjct: 488 E--CTVGYWGLGNHLHGCSP-CDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEP-APGY 543
Query: 405 Y 405
+
Sbjct: 544 F 544
Score = 70.9 bits (172), Expect = 7e-12
Identities = 70/292 (23%), Positives = 97/292 (33%), Gaps = 58/292 (19%)
Query: 542 CDCS-HADGCHPTT--------------GHCRCLPGWSGVHCD---SVCAEGRWGPNCSL 583
C C+ HA C P G C C G +C+ + W P L
Sbjct: 265 CFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCERCKDFFQDAPWRPAADL 324
Query: 584 PCYCKNGASCSPDDGICE-------CAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSG 636
SC+ C + G G C+ C G C + P +
Sbjct: 325 QDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCED-CQHNTEGQHCDRCRP--LFYRD 381
Query: 637 PCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIG 696
P I+ C+P C G GIC ++ + C C G
Sbjct: 382 PLKTISDPYACIP----------CECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEG 431
Query: 697 SDCSQPCPPAHWG-----PNCIHTCNCHN-GAF----CSAYDGECKCTPGWTGLYCTQRC 746
+ C Q C P H+G P C+C+ G+ C G+C C TG +C + C
Sbjct: 432 AKCDQ-CKPNHYGLSATDPLGCQPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHC-EEC 489
Query: 747 PLGFYGKDCALI----CQCQNGAD----CDHISGQCTCRTGFMGRHCEQKCP 790
+G++G L C C G C +GQC CR GR C + P
Sbjct: 490 TVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTGRSCSEPAP 541
Score = 68.9 bits (167), Expect = 3e-11
Identities = 56/195 (28%), Positives = 80/195 (41%), Gaps = 33/195 (16%)
Query: 673 CTCTNNGT----CNPIDRSCQCYPGWIGSDCSQPCPPAHW--GPNCIHTCNCH----NGA 722
C C G+ C+ + CQC P +G C + C + G + H C+CH
Sbjct: 769 CKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDR-CSTGSYDLGHHGCHPCHCHPQGSKDT 827
Query: 723 FCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGAD-CDHISGQCTCRTGFM 781
C G+C C +G C RC G++G C C A+ CD +G C GF
Sbjct: 828 VCDQVTGQCPCHGEVSGRRC-DRCLAGYFGFPSCHPCPCNRFAELCDPETGSCFNCGGFT 886
Query: 782 -GRHCEQKCPSGTYG-----YGCRQICDCLNN-STCDHITGTCY-----------CSPGW 823
GR+CE +C G YG CR C C ++ S+ + +CY C G+
Sbjct: 887 TGRNCE-RCIDGYYGNPSSGQPCRP-CLCPDDPSSNQYFAHSCYQNLWSSDVICNCLQGY 944
Query: 824 KGARCDQAGVIIVGN 838
G +C + GN
Sbjct: 945 TGTQCGECSTGFYGN 959
Score = 65.1 bits (157), Expect = 4e-10
Identities = 70/274 (25%), Positives = 94/274 (34%), Gaps = 55/274 (20%)
Query: 512 GTCTCAPGWRGEKCELPCQDGTYGL----------NCAERCDC-SHADGCHPTTGHCRCL 560
G C C G CE C+D N C C SH+ CH
Sbjct: 293 GQCVCQHNTDGPNCER-CKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLAS 351
Query: 561 PGWSGVHCDSVCAEGRWGPNCSL--PCYCKNGASCSPDDGIC---ECAPGFRGTTCQRIC 615
G SG C+ C G +C P + ++ D C EC P GT IC
Sbjct: 352 GGLSGGVCED-CQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPD--GTISGGIC 408
Query: 616 SPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGI--- 672
HS + G C C GA C++ C +G +
Sbjct: 409 VS---------------HSDPALGSVAGQCLCKENVEGAKCDQ-CKPNHYGLSATDPLGC 452
Query: 673 --CTCTNNG-----TCNPIDRSCQCYPGWIGSDCSQPCPPAHWG-PNCIH---TCNCHNG 721
C C G TC+ C C G+ C + C +WG N +H C+C G
Sbjct: 453 QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEE-CTVGYWGLGNHLHGCSPCDCDIG 511
Query: 722 A----FCSAYDGECKCTPGWTGLYCTQRCPLGFY 751
CS +G+C+C P TG C++ P F+
Sbjct: 512 GAYSNVCSPKNGQCECRPHVTGRSCSEPAPGYFF 545
Score = 50.1 bits (118), Expect = 1e-05
Identities = 67/261 (25%), Positives = 92/261 (35%), Gaps = 75/261 (28%)
Query: 671 GICTCTNNGT-CNPIDR--------------SCQCYPGWIGSDCSQPCPP----AHWGP- 710
G C C + + C P+ + C C G +C + C A W P
Sbjct: 263 GSCFCNGHASECRPMQKMRGDVFSPPGMVHGQCVCQHNTDGPNCER-CKDFFQDAPWRPA 321
Query: 711 -----NCIHTCNCHNGAFCSAYD------------GECK-CTPGWTGLYCTQRCPLGFYG 752
N +C+C++ + +D G C+ C G +C + PL FY
Sbjct: 322 ADLQDNACRSCSCNSHSSRCHFDMTTYLASGGLSGGVCEDCQHNTEGQHCDRCRPL-FYR 380
Query: 753 KDCALI--------CQCQ-----NGADC--------DHISGQCTCRTGFMGRHCEQKCP- 790
I C+C +G C ++GQC C+ G C+Q P
Sbjct: 381 DPLKTISDPYACIPCECDPDGTISGGICVSHSDPALGSVAGQCLCKENVEGAKCDQCKPN 440
Query: 791 ----SGTYGYGCRQICDC-----LNNSTCDHITGTCYCSPGWKGARCDQAGVIIVGNLNS 841
S T GC Q CDC L TCD TG C C GA C++ V G N
Sbjct: 441 HYGLSATDPLGC-QPCDCNPLGSLPFLTCDVDTGQCLCLSYVTGAHCEECTVGYWGLGNH 499
Query: 842 LSRTSTALPADSYQIGAIAGI 862
L S P D GA + +
Sbjct: 500 LHGCS---PCDCDIGGAYSNV 517
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 161 bits (407), Expect = 4e-39
Identities = 124/389 (31%), Positives = 161/389 (41%), Gaps = 70/389 (17%)
Query: 124 CQCEPGWGGTNCSSACDGDH-WGPHCTSRCQC----KNGALCNPITGACHCAAGFRGWRC 178
CQC P G C+ G +GP C+C A CNP+TG CHC G +C
Sbjct: 792 CQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHCFQGVYARQC 851
Query: 179 EDRCEQGTYGNDCHQRCQCQNGA-TCDHVTGECRCPPGYTGAFCEDLCPPGKH------- 230
DRC G +G Q CQC A CD VTGEC YT + C G +
Sbjct: 852 -DRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGYYGDPIIGS 910
Query: 231 GPQCEQRCPCQNG--------GVCHH--VTGE--CSCPSGWMGTVCGQPCPEGRFGK--- 275
G C + CPC +G C+ VT + C C G++G+ C C G FG
Sbjct: 911 GDHC-RPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRC-DDCASGYFGNPSE 968
Query: 276 --NCSQECQCHNG------GTCDAATGQC-HCSPGYTGERCQDECPVGTYGVLCAETC-Q 325
Q CQCHN CD TG+C C GE CQ C G YG + C +
Sbjct: 969 VGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQ-FCRFGYYGDALQQDCRK 1027
Query: 326 CV-----------NGG--KCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRC-PCH 371
CV NG +C +G CLC G+ C+ C + + C PC+
Sbjct: 1028 CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCDR--CAPNTWQLASGTGCDPCN 1085
Query: 372 LENTH----SCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQ------NGADC 421
H SC+ +G+C C PG+ G C+E C F+G+ + +C C
Sbjct: 1086 CNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELFWGDPDVECRACDCDPRGIETPQC 1144
Query: 422 DSVTGKCTCAPGFKGIDCSTPCPLGTYGI 450
D TG+C C G +G C C G G+
Sbjct: 1145 DQSTGQCVCVEGVEGPRCD-KCTRGYSGV 1172
Score = 160 bits (406), Expect = 5e-39
Identities = 132/421 (31%), Positives = 171/421 (40%), Gaps = 85/421 (20%)
Query: 238 CPCQNGG----VCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCS--QECQCHNGGT--- 288
C C G VC G+C C +G C + C G FG S + C+CH G+
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 289 -CDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG--GKCYHVSGACL-CEAG 344
C+ TGQCHC G +C D C G +G + CQC NG C V+G CL C+
Sbjct: 832 FCNPVTGQCHCFQGVYARQC-DRCLPGHWGFPSCQPCQC-NGHADDCDPVTGECLNCQDY 889
Query: 345 FAGERCEARLCPEGLYGIKC------DKRCPC------HLENTHSCH----PMSGECACK 388
G CE C G YG + CPC + SC+ + C C
Sbjct: 890 TMGHNCER--CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCD 947
Query: 389 PGWSGLYCNETCSPGFYGEACQ-----QICSCQNGAD------CDSVTGKC-TCAPGFKG 436
PG+ G C++ C+ G++G + Q C C N D CD TG+C C +G
Sbjct: 948 PGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEG 1006
Query: 437 IDCSTPCPLGTYGINCSS---RCGCK-----------NDAVCSPVDGSCTCKAGWHGVDC 482
C C G YG +C C +D C G C C G +C
Sbjct: 1007 EHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
Query: 483 SIRCPSGTW----GFGCNLTCQC----LNGGACNTLDGTCTCAPGWRGEKCELPCQDGTY 534
RC TW G GC+ C C G +CN G C C PG+ G C CQ+ +
Sbjct: 1066 D-RCAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQELFW 1122
Query: 535 G---LNCAERCDCS----HADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWG--PNCSLPC 585
G + C CDC C +TG C C+ G G CD C G G P+C+ PC
Sbjct: 1123 GDPDVEC-RACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSGVFPDCT-PC 1179
Query: 586 Y 586
+
Sbjct: 1180 H 1180
Score = 149 bits (377), Expect = 1e-35
Identities = 125/414 (30%), Positives = 173/414 (41%), Gaps = 79/414 (19%)
Query: 449 GINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCN--LTCQCLNGGA 506
G+ C +VC P G C C+ G C+ RC GT+GFG + C+C G+
Sbjct: 770 GLACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCN-RCAPGTFGFGPSGCKPCECHLQGS 828
Query: 507 ----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCS-HADGCHPTTGHC-RCL 560
CN + G C C G +C+ C G +G + C C+ HAD C P TG C C
Sbjct: 829 VNAFCNPVTGQCHCFQGVYARQCD-RCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQ 887
Query: 561 PGWSGVHCDSVCAEGRW-------GPNCSLPCYCKNG--------ASCSPD----DGICE 601
G +C+ C G + G +C PC C +G SC D C
Sbjct: 888 DYTMGHNCER-CLAGYYGDPIIGSGDHCR-PCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
Query: 602 CAPGFRGTTCQRICSPGFYGH--RCSQTCPQC-----VHSSGP--CHHITGLC-DCLPGF 651
C PG+ G+ C C+ G++G+ +C C + ++ P C TG C CL
Sbjct: 946 CDPGYIGSRCDD-CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHT 1004
Query: 652 TGALCNEVCPSGRFG----KNCAGICTCTNNGT-----------CNPIDRSCQCYPGWIG 696
G C + C G +G ++C C C GT C+ C C P IG
Sbjct: 1005 EGEHC-QFCRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIG 1062
Query: 697 SDCSQPCPPAHW----GPNCIHTCNCHN----GAFCSAYDGECKCTPGWTGLYCTQRCPL 748
+C + C P W G C CNC+ G C+ + G+C+C PG+ G C++ C
Sbjct: 1063 QNCDR-CAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQE 1119
Query: 749 GFYGK---DCALICQCQ----NGADCDHISGQCTCRTGFMGRHCEQKCPSGTYG 795
F+G +C C C CD +GQC C G G C+ KC G G
Sbjct: 1120 LFWGDPDVECR-ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSG 1171
Score = 143 bits (361), Expect = 8e-34
Identities = 117/409 (28%), Positives = 164/409 (40%), Gaps = 76/409 (18%)
Query: 195 CQCQN----GATCDHVTGECRCPPGYTGAFCEDLCPPGK--HGPQCEQRCPCQNGG---- 244
C+C + CD G+C+C P G C + C PG GP + C C G
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTC-NRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 245 VCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCH-NGGTCDAATGQC-HCSPGY 302
C+ VTG+C C G C + C G +G Q CQC+ + CD TG+C +C
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYT 890
Query: 303 TGERCQDECPVGTYGVLC------AETCQCVNG--------GKCYH----VSGACLCEAG 344
G C + C G YG C C +G CY + AC+C+ G
Sbjct: 891 MGHNC-ERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPG 949
Query: 345 FAGERCEARLCPEGLYGIKCD-----KRCPCH----LENTHSCHPMSGEC-ACKPGWSGL 394
+ G RC+ C G +G + + C CH + +C +G C C G
Sbjct: 950 YIGSRCDD--CASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGE 1007
Query: 395 YCNETCSPGFYGEACQQICS---CQ---------NGAD--CDSVTGKCTCAPGFKGIDCS 440
+C + C G+YG+A QQ C C NG+D CD TG+C C P G +C
Sbjct: 1008 HC-QFCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNCD 1066
Query: 441 TPCPLGTYGINCSSRCG-CKNDAV------CSPVDGSCTCKAGWHGVDCSIRCPSGTWG- 492
C T+ + + C C +A C+ G C C G+ G CS C WG
Sbjct: 1067 R-CAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCS-ECQELFWGD 1124
Query: 493 -----FGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGL 536
C+ + + C+ G C C G G +C+ C G G+
Sbjct: 1125 PDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYSGV 1172
Score = 143 bits (360), Expect = 1e-33
Identities = 127/412 (30%), Positives = 160/412 (38%), Gaps = 82/412 (19%)
Query: 324 CQCVNGGK----CYHVSGACLCEAGFAGERCEARLCPEGLYGIKCD--KRCPCHLENTHS 377
C+C G C G C C G C C G +G K C CHL+ + +
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR--CAPGTFGFGPSGCKPCECHLQGSVN 830
Query: 378 --CHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGAD-CDSVTGKC-TCAPG 433
C+P++G+C C G C+ C PG +G Q C C AD CD VTG+C C
Sbjct: 831 AFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDY 889
Query: 434 FKGIDCSTPCPLGTYG---INCSSRC-----------------GCKNDAVCSPVDGSCTC 473
G +C C G YG I C C D V + +C C
Sbjct: 890 TMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQL--ACVC 946
Query: 474 KAGWHGVDCSIRCPSGTWG-----FGCNLTCQCLNG------GACNTLDGTC-TCAPGWR 521
G+ G C C SG +G G CQC N AC+ G C C
Sbjct: 947 DPGYIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
Query: 522 GEKCELPCQDGTYG---LNCAERCDCS-------HADG----CHPTTGHCRCLPGWSGVH 567
GE C+ C+ G YG +C C+ H +G C TG C CLP G +
Sbjct: 1006 GEHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
Query: 568 CDSVCAEGRW----GPNCSLPCYCKN----GASCSPDDGICECAPGFRGTTCQRICSPGF 619
CD CA W G C PC C G SC+ G C+C PGF G TC C F
Sbjct: 1065 CDR-CAPNTWQLASGTGCD-PCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSE-CQELF 1121
Query: 620 YGH-----RCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFG 666
+G R P+ + + C TG C C+ G G C++ C G G
Sbjct: 1122 WGDPDVECRACDCDPRGIETP-QCDQSTGQCVCVEGVEGPRCDK-CTRGYSG 1171
Score = 139 bits (349), Expect = 2e-32
Identities = 130/432 (30%), Positives = 165/432 (38%), Gaps = 104/432 (24%)
Query: 152 CQCKN----GALCNPITGACHCAAGFRGWRCEDRCEQGTYG------NDCHQRCQCQNGA 201
C+C ++C+P G C C G C +RC GT+G C Q A
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTC-NRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 202 TCDHVTGECRCPPGYTGAFCEDLCPPGKHG-PQCEQRCPCQNGG---VCHHVTGEC-SCP 256
C+ VTG+C C G C D C PG G P C+ PCQ G C VTGEC +C
Sbjct: 832 FCNPVTGQCHCFQGVYARQC-DRCLPGHWGFPSCQ---PCQCNGHADDCDPVTGECLNCQ 887
Query: 257 SGWMGTVCGQ--------------------PCPEG-----RFGKNCSQECQCHNGGTCDA 291
MG C + PCP+G +F ++C Q D
Sbjct: 888 DYTMGHNCERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQ----------DP 937
Query: 292 ATGQ--CHCSPGYTGERCQDECPVGTYGVL-----CAETCQCVNG------GKCYHVSGA 338
T Q C C PGY G RC D+C G +G + CQC N C +G
Sbjct: 938 VTLQLACVCDPGYIGSRC-DDCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGR 996
Query: 339 CL-CEAGFAGERCEARLCPEGLYGIKCD---KRCPCHLENT---------HSCHPMSGEC 385
CL C GE C+ C G YG ++C C+ T C +G+C
Sbjct: 997 CLKCLYHTEGEHCQ--FCRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQC 1054
Query: 386 ACKPGWSGLYCNETCSPGFY----GEACQQICSCQN----GADCDSVTGKCTCAPGFKGI 437
C P G C + C+P + G C C+C G C+ TG+C C PGF G
Sbjct: 1055 LCLPNVIGQNC-DRCAPNTWQLASGTGCDP-CNCNAAHSFGPSCNEFTGQCQCMPGFGGR 1112
Query: 438 DCSTPCPL--GTYGINCSSRCGCKNDAV----CSPVDGSCTCKAGWHGVDCSIRCPSGTW 491
CS L G + C + C C + C G C C G G C +C G
Sbjct: 1113 TCSECQELFWGDPDVECRA-CDCDPRGIETPQCDQSTGQCVCVEGVEGPRCD-KCTRGYS 1170
Query: 492 GF--GCNLTCQC 501
G C QC
Sbjct: 1171 GVFPDCTPCHQC 1182
Score = 138 bits (347), Expect = 3e-32
Identities = 126/405 (31%), Positives = 157/405 (38%), Gaps = 82/405 (20%)
Query: 497 LTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCA--ERCDCSHADG- 549
L C+C G+ C+ G C C P G C C GT+G + + C+C H G
Sbjct: 771 LACECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCEC-HLQGS 828
Query: 550 ----CHPTTGHCRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGIC-EC 602
C+P TG C C G CD C G WG P+C PC C A C P G C C
Sbjct: 829 VNAFCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQ-PCQCNGHADDCDPVTGECLNC 886
Query: 603 APGFRGTTCQRICSPGFYGHRC---SQTCPQCVHSSGP---------CHH----ITGLCD 646
G C+R C G+YG C C GP C+ + C
Sbjct: 887 QDYTMGHNCER-CLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACV 945
Query: 647 CLPGFTGALCNEVCPSGRFGK------NCAGICTCTNN-------------GTC-----N 682
C PG+ G+ C++ C SG FG +C C C NN G C +
Sbjct: 946 CDPGYIGSRCDD-CASGYFGNPSEVGGSCQP-CQCHNNIDTTDPEACDKETGRCLKCLYH 1003
Query: 683 PIDRSCQ-CYPGWIGSDCSQPCPPAHWGPNCIHTCNCH-NGAFCSA--YDGECKCTPGWT 738
CQ C G+ G Q C N + T H NG+ C G+C C P
Sbjct: 1004 TEGEHCQFCRFGYYGDALQQDCRKCVC--NYLGTVQEHCNGSDCQCDKATGQCLCLPNVI 1061
Query: 739 GLYCTQRCPLGFY---GKDCALICQCQN----GADCDHISGQCTCRTGFMGRHCE--QKC 789
G C + P + G C C C G C+ +GQC C GF GR C Q+
Sbjct: 1062 GQNCDRCAPNTWQLASGTGCDP-CNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQEL 1120
Query: 790 PSGTYGYGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
G CR CDC + CD TG C C G +G RCD+
Sbjct: 1121 FWGDPDVECR-ACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK 1164
Score = 134 bits (337), Expect = 5e-31
Identities = 123/437 (28%), Positives = 166/437 (37%), Gaps = 89/437 (20%)
Query: 281 CQCHNGGT----CDAATGQCHCSPGYTGERCQDECPVGTYGV--LCAETCQCVNGGK--- 331
C+C G+ CD GQC C P G C + C GT+G + C+C G
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTC-NRCAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 332 -CYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECA-CKP 389
C V+G C C G +C+ C G +G + C C+ + C P++GEC C+
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDR--CLPGHWGFPSCQPCQCN-GHADDCDPVTGECLNCQD 888
Query: 390 GWSGLYCNETCSPGFYGEA-------CQQICSCQNGADC----------DSVTGK--CTC 430
G C E C G+YG+ C+ C C +G D D VT + C C
Sbjct: 889 YTMGHNC-ERCLAGYYGDPIIGSGDHCRP-CPCPDGPDSGRQFARSCYQDPVTLQLACVC 946
Query: 431 APGFKGIDCSTPCPLGTYG-----------INCSSRCGCKNDAVCSPVDGSC-TCKAGWH 478
PG+ G C C G +G C + + C G C C
Sbjct: 947 DPGYIGSRCD-DCASGYFGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTE 1005
Query: 479 GVDCSIRCPSGTWGFGCNLTC-QCL-----------NGG--ACNTLDGTCTCAPGWRGEK 524
G C C G +G C +C+ NG C+ G C C P G+
Sbjct: 1006 GEHCQF-CRFGYYGDALQQDCRKCVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQN 1064
Query: 525 CELPCQDGTYGLNCAERCD-----CSHADG--CHPTTGHCRCLPGWSGVHCDSVCAEGRW 577
C+ C T+ L CD +H+ G C+ TG C+C+PG+ G C S C E W
Sbjct: 1065 CD-RCAPNTWQLASGTGCDPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTC-SECQELFW 1122
Query: 578 G-PNCSL-PCYCK----NGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQC 631
G P+ C C C G C C G G C + C+ G+ G P C
Sbjct: 1123 GDPDVECRACDCDPRGIETPQCDQSTGQCVCVEGVEGPRCDK-CTRGYSG-----VFPDC 1176
Query: 632 VHSSGPCHHITGLCDCL 648
PCH L D +
Sbjct: 1177 T----PCHQCFALWDVI 1189
Score = 130 bits (327), Expect = 7e-30
Identities = 109/361 (30%), Positives = 146/361 (40%), Gaps = 73/361 (20%)
Query: 542 CDC----SHADGCHPTTGHCRCLPGWSGVHCDSVCAEGR--WGPNCSLPCYC----KNGA 591
C+C S + C P G C+C P G C+ CA G +GP+ PC C A
Sbjct: 773 CECDPQGSLSSVCDPNGGQCQCRPNVVGRTCNR-CAPGTFGFGPSGCKPCECHLQGSVNA 831
Query: 592 SCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLC-DCLPG 650
C+P G C C G C R C PG +G Q C QC + C +TG C +C
Sbjct: 832 FCNPVTGQCHCFQGVYARQCDR-CLPGHWGFPSCQPC-QCNGHADDCDPVTGECLNCQDY 889
Query: 651 FTGALCNEVCPSGRFGKNCAGI------CTCTNNGTCN------------PIDRSCQCYP 692
G C E C +G +G G C C + + +C C P
Sbjct: 890 TMGHNC-ERCLAGYYGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDP 948
Query: 693 GWIGSDCSQPCP-----PAHWGPNCIHTCNCHNG------AFCSAYDGEC-KCTPGWTGL 740
G+IGS C P+ G +C C CHN C G C KC G
Sbjct: 949 GYIGSRCDDCASGYFGNPSEVGGSC-QPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGE 1007
Query: 741 YCTQRCPLGFYG----KDCALICQCQ---------NGAD--CDHISGQCTCRTGFMGRHC 785
+C Q C G+YG +DC C C NG+D CD +GQC C +G++C
Sbjct: 1008 HC-QFCRFGYYGDALQQDCRK-CVCNYLGTVQEHCNGSDCQCDKATGQCLCLPNVIGQNC 1065
Query: 786 EQKCPSGTY----GYGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQAGVIIVG 837
+ +C T+ G GC C+C +C+ TG C C PG+ G C + + G
Sbjct: 1066 D-RCAPNTWQLASGTGC-DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWG 1123
Query: 838 N 838
+
Sbjct: 1124 D 1124
Score = 78.6 bits (192), Expect = 3e-14
Identities = 83/307 (27%), Positives = 108/307 (35%), Gaps = 84/307 (27%)
Query: 88 YRRKSQCCP--GFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH-- 143
Y S+C P GF E E VHG C+ C G NC D H
Sbjct: 274 YGHASECAPVDGFNEEVE--------GMVHGHCM------CRHNTKGLNCELCMDFYHDL 319
Query: 144 -WGP------HCTSRCQCKNGALCNPITGACHCAAG-FRGWRCEDRCEQGTYGNDCHQRC 195
W P + +C C ++ A + A G G C+D C+ T G +C Q
Sbjct: 320 PWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCEQ-- 376
Query: 196 QCQNGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPC-----QNGGVCHHVT 250
C P Y D+ P CE RC C QN G+C T
Sbjct: 377 ----------------CKPFYYQHPERDIRDPNF----CE-RCTCDPAGSQNEGICDSYT 415
Query: 251 --------GECSCPSGWMGTVCGQPCPEGRFGKNCS-----QECQCHNGGT------CDA 291
G+C C G C C EG + + + C C+ GT CD+
Sbjct: 416 DFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDS 474
Query: 292 ATGQCHCSPGYTGERCQDECPVGTYGVL----CAETCQCVNGG----KCYHVSGACLCEA 343
TG C+C TG+ C D+C +G+ C C GG C+ SG C C
Sbjct: 475 ETGHCYCKRLVTGQHC-DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRP 533
Query: 344 GFAGERC 350
G +C
Sbjct: 534 HMIGRQC 540
Score = 76.6 bits (187), Expect = 1e-13
Identities = 72/262 (27%), Positives = 94/262 (35%), Gaps = 69/262 (26%)
Query: 206 VTGECRCPPGYTGAFCEDLC-----------PPGKHGPQCEQRCPCQNGGV-CHHVTGEC 253
V G C C G CE LC G++ C+ +C C + CH
Sbjct: 294 VHGHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNSNACK-KCNCNEHSISCHFDMAVY 351
Query: 254 SCPSGWMGTVCGQPCPEGRFGKNCSQ--------------------ECQC-----HNGGT 288
G VC C G+NC Q C C N G
Sbjct: 352 LATGNVSGGVCDD-CQHNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGI 410
Query: 289 CDAAT--------GQCHCSPGYTGERCQDECPVGTYGVLCAE-----TCQC------VNG 329
CD+ T GQC C GE C D C G Y + + +C C G
Sbjct: 411 CDSYTDFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKSCACNPLGTIPGG 469
Query: 330 GKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCD----KRCPCHLENT--HSCHPMSG 383
C +G C C+ G+ C+ L PE +G+ D + C C L +SC SG
Sbjct: 470 NPCDSETGHCYCKRLVTGQHCDQCL-PEH-WGLSNDLDGCRPCDCDLGGALNNSCFAESG 527
Query: 384 ECACKPGWSGLYCNETCSPGFY 405
+C+C+P G CNE PG+Y
Sbjct: 528 QCSCRPHMIGRQCNEV-EPGYY 548
Score = 70.1 bits (170), Expect = 1e-11
Identities = 78/301 (25%), Positives = 107/301 (35%), Gaps = 84/301 (27%)
Query: 585 CYCKNGAS-CSPDDGI-----------CECAPGFRGTTCQRICSPGFYG-------HRCS 625
C+C AS C+P DG C C +G C+ +C ++ R S
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE-LCMDFYHDLPWRPAEGRNS 329
Query: 626 QTCPQCV--HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNP 683
C +C S CH + +G +C++ C G+NC
Sbjct: 330 NACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDD-CQHNTMGRNCE------------- 375
Query: 684 IDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNC-----HNGAFCSAYD--------GE 730
QC P + Q PN C C N C +Y G+
Sbjct: 376 -----QCKPFYY-----QHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQ 425
Query: 731 CKCTPGWTGLYCTQRCPLGFYG---------KDCAL--ICQCQNGADCDHISGQCTCRTG 779
C+C G +C C GFY K CA + G CD +G C C+
Sbjct: 426 CRCKLNVEGEHCDV-CKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRL 484
Query: 780 FMGRHCEQKCPSGTYGY-----GCRQICDC-----LNNSTCDHITGTCYCSPGWKGARCD 829
G+HC+Q C +G GCR CDC LNNS C +G C C P G +C+
Sbjct: 485 VTGQHCDQ-CLPEHWGLSNDLDGCRP-CDCDLGGALNNS-CFAESGQCSCRPHMIGRQCN 541
Query: 830 Q 830
+
Sbjct: 542 E 542
Score = 63.9 bits (154), Expect = 8e-10
Identities = 78/297 (26%), Positives = 96/297 (32%), Gaps = 62/297 (20%)
Query: 413 CSCQNGA-DCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG-- 469
C C A +C V G G C C T G+NC +D P +G
Sbjct: 271 CFCYGHASECAPVDGFNEEVEGMVHGHCM--CRHNTKGLNCELCMDFYHDLPWRPAEGRN 328
Query: 470 --SCT-CKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCE 526
+C C H + C + L ++GG C+ C G CE
Sbjct: 329 SNACKKCNCNEHSISCH-------FDMAVYLATGNVSGGVCDD------CQHNTMGRNCE 375
Query: 527 LPCQDGTY--------GLNCAERCDCSHADG-----CHPTT--------GHCRCLPGWSG 565
C+ Y N ERC C A C T G CRC G
Sbjct: 376 -QCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRCKLNVEG 434
Query: 566 VHCDSVCAEGRWGPNCSLPCYCKN-----------GASCSPDDGICECAPGFRGTTCQRI 614
HCD VC EG + + P CK+ G C + G C C G C +
Sbjct: 435 EHCD-VCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCDQ- 492
Query: 615 CSPGFYG-HRCSQTCPQCVHSSG-----PCHHITGLCDCLPGFTGALCNEVCPSGRF 665
C P +G C C G C +G C C P G CNEV P F
Sbjct: 493 CLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPGYYF 549
Score = 61.2 bits (147), Expect = 5e-09
Identities = 77/305 (25%), Positives = 101/305 (33%), Gaps = 70/305 (22%)
Query: 534 YGLNCAERCDC-SHADGCHPTTG-----------HCRCLPGWSGVHCDSVC--------- 572
Y + C C HA C P G HC C G++C+ +C
Sbjct: 263 YDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKGLNCE-LCMDFYHDLPW 321
Query: 573 --AEGRWGPNCSLPCYC-KNGASCSPD-----------DGICE-CAPGFRGTTCQRICSP 617
AEGR N C C ++ SC D G+C+ C G C++ C P
Sbjct: 322 RPAEGR-NSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQHNTMGRNCEQ-CKP 379
Query: 618 GFYGH-----RCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGI 672
+Y H R C +C + G+CD F+ L AG
Sbjct: 380 FYYQHPERDIRDPNFCERCTCDPAGSQN-EGICDSYTDFSTGLI-------------AGQ 425
Query: 673 CTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECK 732
C C N D C G+ P N + T G C + G C
Sbjct: 426 CRCKLNVEGEHCD---VCKEGFYDLSSEDPFGCKSCACNPLGTIP--GGNPCDSETGHCY 480
Query: 733 CTPGWTGLYCTQRCPLGF---YGKDCALICQCQNGA----DCDHISGQCTCRTGFMGRHC 785
C TG +C Q P + D C C G C SGQC+CR +GR C
Sbjct: 481 CKRLVTGQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQC 540
Query: 786 EQKCP 790
+ P
Sbjct: 541 NEVEP 545
Score = 47.8 bits (112), Expect = 6e-05
Identities = 62/265 (23%), Positives = 86/265 (32%), Gaps = 47/265 (17%)
Query: 249 VTGECSCPSGWMGTVCGQPC-----------PEGRFGKNCSQECQCHNGGTCDAATGQCH 297
V G C C G C + C EGR N ++C C+ +
Sbjct: 294 VHGHCMCRHNTKGLNC-ELCMDFYHDLPWRPAEGR-NSNACKKCNCNEHSISCHFDMAVY 351
Query: 298 CSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPE 357
+ G D+C T G C E C+ Y + + F ERC
Sbjct: 352 LATGNVSGGVCDDCQHNTMGRNC-EQCKPFY----YQHPERDIRDPNFC-ERCTCDPAGS 405
Query: 358 GLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGE---------- 407
GI C S ++G+C CK G +C + C GFY
Sbjct: 406 QNEGI-------CDSYTDFSTGLIAGQCRCKLNVEGEHC-DVCKEGFYDLSSEDPFGCKS 457
Query: 408 -ACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGIN--------CSSRCGC 458
AC + + G CDS TG C C G C C +G++ C G
Sbjct: 458 CACNPLGTIPGGNPCDSETGHCYCKRLVTGQHCD-QCLPEHWGLSNDLDGCRPCDCDLGG 516
Query: 459 KNDAVCSPVDGSCTCKAGWHGVDCS 483
+ C G C+C+ G C+
Sbjct: 517 ALNNSCFAESGQCSCRPHMIGRQCN 541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 44/178 (24%), Positives = 66/178 (37%), Gaps = 38/178 (21%)
Query: 86 TMYRRKSQCCPGFYESGEMCV--PHCADKCV--------HGRC---------IAPNTCQC 126
TM R QC P +Y+ E + P+ ++C G C + C+C
Sbjct: 369 TMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQCRC 428
Query: 127 EPGWGGTNCSSACDGDH----WGPHCTSRCQCK------NGALCNPITGACHCAAGFRGW 176
+ G +C +G + P C C G C+ TG C+C G
Sbjct: 429 KLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVTGQ 488
Query: 177 RCEDRCEQGTYG--NDCH--QRCQCQNGA----TCDHVTGECRCPPGYTGAFCEDLCP 226
C D+C +G ND + C C G +C +G+C C P G C ++ P
Sbjct: 489 HC-DQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEP 545
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 150 bits (380), Expect = 5e-36
Identities = 115/386 (29%), Positives = 153/386 (39%), Gaps = 101/386 (26%)
Query: 89 RRKSQCCPGF---YESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWG 145
R + C PG+ Y + +C+P C ++ HG C P C+C GW G C
Sbjct: 207 RGEKVCNPGWKGPYCTEPICLPGCDEQ--HGFCDKPGECKCRVGWQGRYCD--------- 255
Query: 146 PHCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDH 205
C C +G P C+C G+ G C N C C+NGATC +
Sbjct: 256 -ECIRYPGCLHGTCQQP--WQCNCQEGWGGLFCNQDL------NYCTHHKPCKNGATCTN 306
Query: 206 VTGE----CRCPPGYTGAFCE---DLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCP 256
TG+ C C PGYTGA CE D C P PC+NGG C + C+CP
Sbjct: 307 -TGQGSYTCSCRPGYTGATCELGIDECDPS----------PCKNGGSCTDLENSYSCTCP 355
Query: 257 SGWMGTVC---GQPCPEGRFGKNCSQECQCHNGGTC-DAATG--QCHCSPGYTGERCQDE 310
G+ G +C C +G C NGG C D+ G C C GY+G C+ +
Sbjct: 356 PGFYGKICELSAMTCADG----------PCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKK 405
Query: 311 CPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRC 368
+ + C NG KC + A C C+AGF+G C+
Sbjct: 406 -------IDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCD----------------- 441
Query: 369 PCHLENTHSC--HPMSGECACKPGWSGLYCNETCSPGFYGEACQQICS------CQNGAD 420
+N C P + C+ G + C TC PG+ G C S C NGA
Sbjct: 442 ----DNVDDCASSPCANGGTCRDGVNDFSC--TCPPGYTGRNCSAPVSRCEHAPCHNGAT 495
Query: 421 CDSVTGK--CTCAPGFKGIDCSTPCP 444
C + C CA G+ G +C P
Sbjct: 496 CHERGHRYVCECARGYGGPNCQFLLP 521
Score = 135 bits (341), Expect = 2e-31
Identities = 121/426 (28%), Positives = 167/426 (39%), Gaps = 115/426 (26%)
Query: 268 CPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCV 327
C E +G+ CS C+ D A G C GER + C G G C E C+
Sbjct: 179 CDEHYYGEGCSVFCRPR-----DDAFGHFTC-----GERGEKVCNPGWKGPYCTEPI-CL 227
Query: 328 NGGKCYH----VSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSG 383
G H G C C G+ G C+ +C + C H
Sbjct: 228 PGCDEQHGFCDKPGECKCRVGWQGRYCD-----------ECIRYPGC----LHGTCQQPW 272
Query: 384 ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGK----CTCAPGFKGIDC 439
+C C+ GW GL+CN+ + C C+NGA C + TG+ C+C PG+ G C
Sbjct: 273 QCNCQEGWGGLFCNQDLN------YCTHHKPCKNGATCTN-TGQGSYTCSCRPGYTGATC 325
Query: 440 STPCPLGTYGINCSSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSIRCPSGTWGFGCNL 497
GI+ CKN C+ ++ SCTC G++G C + +
Sbjct: 326 E-------LGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSA----------M 368
Query: 498 TC---QCLNGGAC-NTLDG--TCTCAPGWRGEKCE--------LPCQDGTYGLNCAERCD 543
TC C NGG C ++ DG +C C G+ G CE PC +G C + D
Sbjct: 369 TCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGA---KCVDLGD 425
Query: 544 CSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
CRC G+SG HCD + P C NG +C DG+ + +
Sbjct: 426 AY----------LCRCQAGFSGRHCDDNVDDCASSP-------CANGGTCR--DGVNDFS 466
Query: 604 PGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCH-----HITG---LCDCLPGFTGAL 655
TC PG+ G CS +C H+ PCH H G +C+C G+ G
Sbjct: 467 -----CTC----PPGYTGRNCSAPVSRCEHA--PCHNGATCHERGHRYVCECARGYGGPN 515
Query: 656 CNEVCP 661
C + P
Sbjct: 516 CQFLLP 521
Score = 110 bits (276), Expect = 6e-24
Identities = 117/464 (25%), Positives = 163/464 (35%), Gaps = 132/464 (28%)
Query: 516 CAPGWRGEKCELPCQ--DGTYG-LNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVC 572
C + GE C + C+ D +G C ER G C PGW G +C
Sbjct: 179 CDEHYYGEGCSVFCRPRDDAFGHFTCGER-------------GEKVCNPGWKGPYCTE-- 223
Query: 573 AEGRWGPNCSLPCYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCV 632
P C C ++G P G C+C G++G C P C+
Sbjct: 224 ------PICLPGCDEQHGFCDKP--GECKCRVGWQGRYCDECIR-----------YPGCL 264
Query: 633 HSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYP 692
H G C C+C G+ G CN+ K C TCTN G + +C C P
Sbjct: 265 H--GTCQQ-PWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGS---YTCSCRP 318
Query: 693 GWIGSDC-------------------------SQPCPPAHWGPNC---IHTC---NCHNG 721
G+ G+ C S CPP +G C TC C NG
Sbjct: 319 GYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNG 378
Query: 722 AFCS-AYDG--ECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ--CTC 776
CS + DG C+C G++G C ++ D C NGA C + C C
Sbjct: 379 GRCSDSPDGGYSCRCPVGYSGFNCEKKI-------DYCSSSPCSNGAKCVDLGDAYLCRC 431
Query: 777 RTGFMGRHCEQK-------------------------CPSGTYGYGCR------QICDCL 805
+ GF GRHC+ CP G G C + C
Sbjct: 432 QAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCH 491
Query: 806 NNSTCDHITG---TCYCSPGWKGARCD------QAGVIIVGNLNSLSRTSTALPADSYQI 856
N +TC H G C C+ G+ G C G +V L P +
Sbjct: 492 NGATC-HERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQGGPFP----WV 546
Query: 857 GAIAGIIILVLVVLFLLALFIIYRHK-QKGKESSMPAVTYTPAM 899
AG+I++++++L A+ + R + QK + + P T M
Sbjct: 547 AVCAGVILVLMLLLGCAAVVVCVRLRLQKHRPPADPCRGETETM 590
Score = 79.0 bits (193), Expect = 2e-14
Identities = 85/306 (27%), Positives = 105/306 (34%), Gaps = 96/306 (31%)
Query: 614 ICSPGFYGHRCSQTCPQCVHSSGPCHHIT----GLCDCLPGFTGALCNE-VCP------- 661
+C +YG CS C + G H T G C PG+ G C E +C
Sbjct: 178 VCDEHYYGEGCSVFCRPRDDAFG---HFTCGERGEKVCNPGWKGPYCTEPICLPGCDEQH 234
Query: 662 ---------------SGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPC--- 703
GR+ C C +GTC C C GW G C+Q
Sbjct: 235 GFCDKPGECKCRVGWQGRYCDECIRYPGCL-HGTCQQ-PWQCNCQEGWGGLFCNQDLNYC 292
Query: 704 ---PPAHWGPNCI------HTCNC---HNGAFCSAYDGECKCTPGWTGLYCTQ------- 744
P G C +TC+C + GA C EC +P G CT
Sbjct: 293 THHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSC 352
Query: 745 RCPLGFYGKDC---ALIC---QCQNGADC-DHISG--QCTCRTGFMGRHCEQK------- 788
CP GFYGK C A+ C C NG C D G C C G+ G +CE+K
Sbjct: 353 TCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSS 412
Query: 789 ------------------CPSGTYGYGCRQICD------CLNNSTC-DHITG-TCYCSPG 822
C +G G C D C N TC D + +C C PG
Sbjct: 413 PCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPG 472
Query: 823 WKGARC 828
+ G C
Sbjct: 473 YTGRNC 478
Score = 75.9 bits (185), Expect = 2e-13
Identities = 69/219 (31%), Positives = 86/219 (39%), Gaps = 78/219 (35%)
Query: 59 SCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMC---VPHCAD-KCV 114
SCTD+ N + CT C PGFY G++C CAD C
Sbjct: 342 SCTDLENSYSCT-----------------------CPPGFY--GKICELSAMTCADGPCF 376
Query: 115 HG-RCI-APN---TCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGA--C 167
+G RC +P+ +C+C G+ G NC D +C+S C NGA C + A C
Sbjct: 377 NGGRCSDSPDGGYSCRCPVGYSGFNCEKKID------YCSSS-PCSNGAKCVDLGDAYLC 429
Query: 168 HCAAGFRGWRCEDR-------------------------CEQGTYGNDCH---QRCQ--- 196
C AGF G C+D C G G +C RC+
Sbjct: 430 RCQAGFSGRHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAP 489
Query: 197 CQNGATCDHVTGE---CRCPPGYTGAFCEDLCPPGKHGP 232
C NGATC H G C C GY G C+ L P GP
Sbjct: 490 CHNGATC-HERGHRYVCECARGYGGPNCQFLLPELPPGP 527
>gi|209571555 von Willebrand factor D and EGF domains [Homo sapiens]
Length = 1590
Score = 145 bits (365), Expect = 3e-34
Identities = 110/342 (32%), Positives = 143/342 (41%), Gaps = 86/342 (25%)
Query: 93 QCCPGFYESG---EMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCT 149
+C PG+ S +C P C + HG+CI PN CQC PG GG + CD +H P C
Sbjct: 1315 KCKPGYIGSNCQTALCDPDCKN---HGKCIKPNICQCLPGHGG----ATCDEEHCNPPCQ 1367
Query: 150 SRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGE 209
C G LC C GF G RCE C++ C+NG C +T +
Sbjct: 1368 HGGTCLAGNLCT-------CPYGFVGPRCETMV--------CNR--HCENGGQC--LTPD 1408
Query: 210 -CRCPPGYTGAFCED-LCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQP 267
C+C PG+ G C LC P C NGG C+ C CP+G+ G C
Sbjct: 1409 ICQCKPGWYGPTCSTALCDP-----------VCLNGGSCNK-PNTCLCPNGFFGEHC--- 1453
Query: 268 CPEGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCV 327
+N C NGG C C C GYTG R Q +C T C+
Sbjct: 1454 -------QNAFCHPPCKNGGHC-MRNNVCVCREGYTGRRFQKS--------ICDPT--CM 1495
Query: 328 NGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECAC 387
NGGKC S C C +G++G+RC +C + KC C + C C
Sbjct: 1496 NGGKCVGPS-TCSCPSGWSGKRCNTPICLQ-----KCKNGGECIAPSI---------CHC 1540
Query: 388 KPGWSGLYCN-ETCSPG-FYGEAC--QQICSCQ---NGADCD 422
W G+ C C+P YG C +CSC+ +G C+
Sbjct: 1541 PSSWEGVRCQIPICNPKCLYGGRCIFPNVCSCRTEYSGVKCE 1582
Score = 122 bits (306), Expect = 2e-27
Identities = 131/509 (25%), Positives = 166/509 (32%), Gaps = 153/509 (30%)
Query: 152 CQCKNGALC------NPITGA--CHCAAGFRGWRCE--------DRCEQGTYGNDCHQRC 195
C C NG C +P +G C C GF G CE + C G+Y + H
Sbjct: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYISGFHSY- 1239
Query: 196 QCQNGATCDHVTGECRCPPG------YTGAFCEDLCPPGKHGPQCEQRCPCQNG-GVCHH 248
C CPP + F + + +N G H
Sbjct: 1240 -------------SCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRH 1286
Query: 249 VTGECSCPSGWMGTVCGQPCPEGR--------------FGKNCSQ---ECQCHNGGTCDA 291
V SG T+C PC + R G NC + C N G C
Sbjct: 1287 VKPT----SGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHGKC-I 1341
Query: 292 ATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCE 351
C C PG+ G C +E C CQ +GG C C C GF G RCE
Sbjct: 1342 KPNICQCLPGHGGATCDEEH--------CNPPCQ--HGGTCL-AGNLCTCPYGFVGPRCE 1390
Query: 352 ARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNET-CSPGFYGEACQ 410
+C H EN C C CKPGW G C+ C P
Sbjct: 1391 TMVCNR-------------HCENGGQCLTPD-ICQCKPGWYGPTCSTALCDP-------- 1428
Query: 411 QICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGS 470
C NG C+ C C GF G C N CKN C +
Sbjct: 1429 ---VCLNGGSCNK-PNTCLCPNGFFGEHCQ----------NAFCHPPCKNGGHCMR-NNV 1473
Query: 471 CTCKAGWHG--VDCSIRCPSGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP 528
C C+ G+ G SI P+ C+NGG C TC+C GW G++C P
Sbjct: 1474 CVCREGYTGRRFQKSICDPT------------CMNGGKC-VGPSTCSCPSGWSGKRCNTP 1520
Query: 529 CQDGTYGLNCAERC----DCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLP 584
C ++C +C CH C W GV C P C+
Sbjct: 1521 I--------CLQKCKNGGECIAPSICH-------CPSSWEGVRCQI--------PICNPK 1557
Query: 585 CYCKNGASCSPDDGICECAPGFRGTTCQR 613
C G P+ +C C + G C++
Sbjct: 1558 C-LYGGRCIFPN--VCSCRTEYSGVKCEK 1583
Score = 108 bits (271), Expect = 2e-23
Identities = 122/477 (25%), Positives = 160/477 (33%), Gaps = 178/477 (37%)
Query: 306 RCQDECPVGTYGVL--CAETCQCVNGGKCYH------VSGA--CLCEAGFAGERCEARLC 355
R D+C T + ++C C+NGG C SG C+C GF G CE +
Sbjct: 1161 RLNDDCDAETRVTIEVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDIS 1220
Query: 356 P------------EGLYGIKCDKRCPCHLE------------------------------ 373
G + CD CP L+
Sbjct: 1221 GCQSNPCGLGSYISGFHSYSCD--CPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDK 1278
Query: 374 ----NTHSCHPMSGE--------------------CACKPGWSGLYCNET---------- 399
P SG C CKPG+ G C
Sbjct: 1279 NAQGRKRHVKPTSGNAFTICKYPCGKSRECVAPNICKCKPGYIGSNCQTALCDPDCKNHG 1338
Query: 400 ---------CSPGFYGEAC-QQICS--CQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGT 447
C PG G C ++ C+ CQ+G C CTC GF G C T
Sbjct: 1339 KCIKPNICQCLPGHGGATCDEEHCNPPCQHGGTC-LAGNLCTCPYGFVGPRCET------ 1391
Query: 448 YGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGAC 507
+ C+ C+N C D C CK GW+G CS C+ CLNGG+C
Sbjct: 1392 --MVCNRH--CENGGQCLTPD-ICQCKPGWYGPTCSTAL--------CDPV--CLNGGSC 1436
Query: 508 NTLDGTCTCAPGWRGEKCE-----LPCQDGTYGLN-----CAER----------CD--CS 545
N TC C G+ GE C+ PC++G + + C E CD C
Sbjct: 1437 NK-PNTCLCPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKSICDPTCM 1495
Query: 546 HADGC-HPTTGHCRCLPGWSGVHCDS-VCAEGRWGPNCSLPCYCKNGASCSPDDGICECA 603
+ C P+T C C GWSG C++ +C + CKNG C IC C
Sbjct: 1496 NGGKCVGPST--CSCPSGWSGKRCNTPICLQ-----------KCKNGGECIA-PSICHCP 1541
Query: 604 PGFRGTTCQ-RICSPG-FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNE 658
+ G CQ IC+P YG RC +C C ++G C +
Sbjct: 1542 SSWEGVRCQIPICNPKCLYGGRCI---------------FPNVCSCRTEYSGVKCEK 1583
Score = 105 bits (263), Expect = 2e-22
Identities = 122/469 (26%), Positives = 160/469 (34%), Gaps = 146/469 (31%)
Query: 407 EACQQICSCQNGADCDSVTG--------KCTCAPGFKGIDC--------STPCPLGTY-- 448
E + C C NG C S C C PGF G C S PC LG+Y
Sbjct: 1175 EVTVKSCDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCEVDISGCQSNPCGLGSYIS 1234
Query: 449 GINCSSRCGCKND---------------AVCSPVDGSCTCKAGWHGVDCSIRCPSGTWG- 492
G + S C C + V + D S + R T G
Sbjct: 1235 GFHSYS-CDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
Query: 493 ------FGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSH 546
+ C + +C+ C C PG+ G C+ D DC +
Sbjct: 1294 AFTICKYPCGKSRECV-------APNICKCKPGYIGSNCQTALCDP----------DCKN 1336
Query: 547 ADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICECAPGF 606
C C+CLPG G CD +C+ PC ++G +C + +C C GF
Sbjct: 1337 HGKCIKPN-ICQCLPGHGGATCDE--------EHCNPPC--QHGGTCLAGN-LCTCPYGF 1384
Query: 607 RGTTCQRI-------------------CSPGFYGHRCSQT-CPQCVHSSGPCHHITGLCD 646
G C+ + C PG+YG CS C + G C+ C
Sbjct: 1385 VGPRCETMVCNRHCENGGQCLTPDICQCKPGWYGPTCSTALCDPVCLNGGSCNK-PNTCL 1443
Query: 647 CLPGFTG-----ALCNEVCPSG------------------RFGKNCAGIC--TCTNNGTC 681
C GF G A C+ C +G RF K+ IC TC N G C
Sbjct: 1444 CPNGFFGEHCQNAFCHPPCKNGGHCMRNNVCVCREGYTGRRFQKS---ICDPTCMNGGKC 1500
Query: 682 NPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWTGLY 741
+C C GW G C+ P C+ C NG C A C C W G+
Sbjct: 1501 VG-PSTCSCPSGWSGKRCNTPI--------CLQ--KCKNGGECIA-PSICHCPSSWEGVR 1548
Query: 742 CTQRCPLGFYGKDCALIC--QCQNGADCDHISGQCTCRTGFMGRHCEQK 788
C + P IC +C G C C+CRT + G CE+K
Sbjct: 1549 C--QIP----------ICNPKCLYGGRC-IFPNVCSCRTEYSGVKCEKK 1584
Score = 94.0 bits (232), Expect = 7e-19
Identities = 99/377 (26%), Positives = 124/377 (32%), Gaps = 128/377 (33%)
Query: 542 CDCSHADGC------HPTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC 593
CDC + C P +G C CLPG+ G C+ V G C L Y S
Sbjct: 1181 CDCLNGGSCVSDRNFSPGSGVYLCVCLPGFHGSLCE-VDISGCQSNPCGLGSYISGFHSY 1239
Query: 594 SPDDGICECAPGFRGTTC-------------------------------QRICSP--GFY 620
S C+C P + T +R P G
Sbjct: 1240 S-----CDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGNA 1294
Query: 621 GHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGIC--TCTNN 678
C C + P +C C PG+ G+ C +C C N+
Sbjct: 1295 FTICKYPCGKSRECVAP-----NICKCKPGYIGSNCQ------------TALCDPDCKNH 1337
Query: 679 GTCNPIDRSCQCYPGWIGSDCSQ-------------------PCPPAHWGPNC-IHTCN- 717
G C CQC PG G+ C + CP GP C CN
Sbjct: 1338 GKCIK-PNICQCLPGHGGATCDEEHCNPPCQHGGTCLAGNLCTCPYGFVGPRCETMVCNR 1396
Query: 718 -CHNGAFCSAYDGECKCTPGWTGLYC-------------------TQRCPLGFYGKDCA- 756
C NG C D C+C PGW G C T CP GF+G+ C
Sbjct: 1397 HCENGGQCLTPD-ICQCKPGWYGPTCSTALCDPVCLNGGSCNKPNTCLCPNGFFGEHCQN 1455
Query: 757 LICQ--CQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQICD--CLNNSTCDH 812
C C+NG C + C CR G+ GR + + ICD C+N C
Sbjct: 1456 AFCHPPCKNGGHCMR-NNVCVCREGYTGRRFQ------------KSICDPTCMNGGKCVG 1502
Query: 813 ITGTCYCSPGWKGARCD 829
TC C GW G RC+
Sbjct: 1503 -PSTCSCPSGWSGKRCN 1518
Score = 73.9 bits (180), Expect = 8e-13
Identities = 79/287 (27%), Positives = 99/287 (34%), Gaps = 83/287 (28%)
Query: 585 CYCKNGASCSPDDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPC---HHI 641
C C NG SC D +PG C +C PGF+G C C S PC +I
Sbjct: 1181 CDCLNGGSCVSDRNF---SPGSGVYLC--VCLPGFHGSLCEVDISGC--QSNPCGLGSYI 1233
Query: 642 TGL----CDCLPG------FTGALCNEVCPSGRFGK-----------------------N 668
+G CDC P F + R K N
Sbjct: 1234 SGFHSYSCDCPPELKVETQFVNQFTTQTVVLTRSDKSVNKEEDDKNAQGRKRHVKPTSGN 1293
Query: 669 CAGICT--CTNNGTCNPIDRSCQCYPGWIGSDCSQP-CPPAHWGPNCIHTCNCHNGAFCS 725
IC C + C C+C PG+IGS+C C P +C N C
Sbjct: 1294 AFTICKYPCGKSREC-VAPNICKCKPGYIGSNCQTALCDP-----------DCKNHGKCI 1341
Query: 726 AYDGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ-CTCRTGFMGRH 784
C+C PG G C + + C CQ+G C ++G CTC GF+G
Sbjct: 1342 K-PNICQCLPGHGGATCDE--------EHCNP--PCQHGGTC--LAGNLCTCPYGFVGPR 1388
Query: 785 CEQKCPSGTYGYGCRQICDCLNNSTCDHITGTCYCSPGWKGARCDQA 831
CE C + C+ N C C C PGW G C A
Sbjct: 1389 CETMV--------CNRHCE--NGGQC-LTPDICQCKPGWYGPTCSTA 1424
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 145 bits (365), Expect = 3e-34
Identities = 145/524 (27%), Positives = 203/524 (38%), Gaps = 145/524 (27%)
Query: 373 ENTHSCHPMS--GECACKPGWSGLY--CNETCSPGFYGEACQQICSCQNGADCDSVTGK- 427
+N +C S +C+C + L C+ P F CQ A C + G+
Sbjct: 40 QNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP-------CQGSATCVNTPGER 92
Query: 428 ---CTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC--SPVDGSCTCKAGWHGVDC 482
C C PG+ G C T +G+ G N C++ +C P+ C C AG+ G C
Sbjct: 93 SFLCKCPPGYSGTICETT--IGSCGKN-----SCQHGGICHQDPIYPVCICPAGYAGRFC 145
Query: 483 SI---RCPSGTWGFGCNLTCQCLNGGACNT-LDG-TCTCAPGWRGEKCELPCQDGTYGLN 537
I C S C NG C +DG +C C PG++G C+L +
Sbjct: 146 EIDHDECASSP----------CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDE------ 189
Query: 538 CAERCDCSHADGCHPTTGH--CRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSP 595
CA C + C G C C +SGV+C+ E P C NGA+C
Sbjct: 190 CASD-PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQP-------CLNGATCQD 241
Query: 596 DDGICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLC---------D 646
G C C+PGF G C +C +S PC H GLC +
Sbjct: 242 ALGAYFCD-----------CAPGFLGDHCELNTDEC--ASQPCLH-GGLCVDGENRYSCN 287
Query: 647 CL-PGFTGALCNEVCPSGRFGKNCAGIC---TCTNNGTC-NPIDR-SCQCYPGWIGSDC- 699
C GFTG C + P +C C NN TC + +D +C C+PG+ G+ C
Sbjct: 288 CTGSGFTGTHCETLMP----------LCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCE 337
Query: 700 -------SQPCPPAHWGPNCIHTCN----------CHNGAFCSAYDGECKCTPGWTGLYC 742
S PC C+ + + ++ A C C PG+TG++C
Sbjct: 338 IDLNECNSNPCQS---NGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHC 394
Query: 743 TQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQKCPSGTYGYGCRQIC 802
+ +C+ CQNG C+++ G TC HC S T+ YG R
Sbjct: 395 EEDV------NECSSN-PCQNGGTCENLPGNYTC-------HCPFDNLSRTF-YGGRDCS 439
Query: 803 D---------CLNNSTC-DHITG-----TCYCSPGWKGARCDQA 831
D CLNN TC H +C C G+ G+ C+ A
Sbjct: 440 DILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIA 483
Score = 143 bits (360), Expect = 1e-33
Identities = 151/518 (29%), Positives = 202/518 (38%), Gaps = 114/518 (22%)
Query: 283 CHNGGTCDAATGQCHCSPGYTGERCQDECPV---GTYGVLCAETCQCVN--GGKCYHVSG 337
C N TC + CS T +C + C + CVN G + +
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVNTPGERSF---- 94
Query: 338 ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYC- 396
C C G++G CE + G C CH + P+ C C G++G +C
Sbjct: 95 LCKCPPGYSGTICETTIGSCGKNS--CQHGGICHQD------PIYPVCICPAGYAGRFCE 146
Query: 397 --NETCSPGFYGEACQQICSCQNGADC-DSVTG-KCTCAPGFKGIDCSTPCPLGTYGINC 452
++ C+ CQNGA C D + G C C PG++G C C
Sbjct: 147 IDHDECASS----------PCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD------EC 190
Query: 453 SSRCGCKNDAVCSPVDG--SCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQCLNGGACNTL 510
+S CKN+A C G +C C + GV+C + W + CLNG C
Sbjct: 191 ASD-PCKNEATCLNEIGRYTCICPHNYSGVNCELEIDE-CW------SQPCLNGATCQDA 242
Query: 511 DGT--CTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGH--CRCL-PGWSG 565
G C CAPG+ G+ CEL + CA + C H C C C G++G
Sbjct: 243 LGAYFCDCAPGFLGDHCELNTDE------CASQ-PCLHGGLCVDGENRYSCNCTGSGFTG 295
Query: 566 VHCDSVCAEGRWGPNC-SLPCYCKNGASC--SPDDGICECAPGFRGTTCQRICSPGFYGH 622
HC+++ P C S PC+ N A+C S D+ C C PG+ G C+ I +
Sbjct: 296 THCETLM------PLCWSKPCH--NNATCEDSVDNYTCHCWPGYTGAQCE-IDLNECNSN 346
Query: 623 RCSQTCPQCVHSSGPCHH--ITGL-------------CDCLPGFTGALCNE---VCPSGR 664
C Q+ +CV S + ITGL C C PGFTG C E C S
Sbjct: 347 PC-QSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSS-- 403
Query: 665 FGKNCAGICTCTN---NGTCN-PIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHN 720
C TC N N TC+ P D + + G G DCS C H C N
Sbjct: 404 --NPCQNGGTCENLPGNYTCHCPFDNLSRTFYG--GRDCSDIL------LGCTHQ-QCLN 452
Query: 721 GAFCSAY--DGE----CKCTPGWTGLYCTQRCPLGFYG 752
C + DG+ C C G+TG C L F G
Sbjct: 453 NGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLSFEG 490
Score = 142 bits (358), Expect = 2e-33
Identities = 130/467 (27%), Positives = 172/467 (36%), Gaps = 143/467 (30%)
Query: 124 CQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC--NPITGACHCAAGFRGWRCE-- 179
C+C PG+ GT C + + C++G +C +PI C C AG+ G CE
Sbjct: 96 CKCPPGYSGTICETTIGS-------CGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID 148
Query: 180 -DRCEQGTYGNDCHQRCQCQNGATC-DHVTG-ECRCPPGYTGAFCE---DLCPPGKHGPQ 233
D C CQNGA C D + G C C PGY G C+ D C
Sbjct: 149 HDECASS----------PCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD----- 193
Query: 234 CEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCS---QEC---QCHNGG 287
PC+N C + G +C CP G NC EC C NG
Sbjct: 194 -----PCKNEATCLNEIGRYTC-----------ICPHNYSGVNCELEIDECWSQPCLNGA 237
Query: 288 TCDAATGQ--CHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGACLCE 342
TC A G C C+PG+ G+ C+ DEC + C++GG C C
Sbjct: 238 TCQDALGAYFCDCAPGFLGDHCELNTDEC----------ASQPCLHGGLCVDGENRYSCN 287
Query: 343 ---AGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCN-- 397
+GF G CE L P C + PCH T + C C PG++G C
Sbjct: 288 CTGSGFTGTHCET-LMP------LCWSK-PCHNNATCEDSVDNYTCHCWPGYTGAQCEID 339
Query: 398 -ETCSPGFYGEACQQICSCQNGADCDSVTGK----------------------CTCAPGF 434
C+ CQ+ +C ++ + C C PGF
Sbjct: 340 LNECNSN----------PCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGF 389
Query: 435 KGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTC--------KAGWHGVDCSIRC 486
GI C +N S C+N C + G+ TC + + G DCS
Sbjct: 390 TGIHCEE-------DVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDIL 442
Query: 487 PSGTWGFGCNLTCQCLNGGAC--NTLDG----TCTCAPGWRGEKCEL 527
GC QCLN G C + DG +C C G+ G CE+
Sbjct: 443 ------LGCTHQ-QCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 125 bits (315), Expect = 2e-28
Identities = 126/439 (28%), Positives = 171/439 (38%), Gaps = 128/439 (29%)
Query: 95 CPGFYESGEMC-VPHCADKCVHGRCIAPNTCQ---------CEPGWGGTNCSSACDGDHW 144
CP Y +G C + H D+C C CQ C PG+ G +C D
Sbjct: 136 CPAGY-AGRFCEIDH--DECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVD---- 188
Query: 145 GPHCTSRCQCKNGALCNPITG--ACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGAT 202
C S CKN A C G C C + G CE + +C + C NGAT
Sbjct: 189 --ECASD-PCKNEATCLNEIGRYTCICPHNYSGVNCELEID------ECWSQ-PCLNGAT 238
Query: 203 CDHVTGE--CRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE----CSCP 256
C G C C PG+ G CE + +C + PC +GG+C V GE C+C
Sbjct: 239 CQDALGAYFCDCAPGFLGDHCE------LNTDECASQ-PCLHGGLC--VDGENRYSCNCT 289
Query: 257 -SGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQ---DE 310
SG+ GT C P CHN TC+ + CHC PGYTG +C+ +E
Sbjct: 290 GSGFTGTHCETLMP-------LCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNE 342
Query: 311 CPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIKCDKRCPC 370
C + C + G+C +S E+ R+
Sbjct: 343 C----------NSNPCQSNGECVELS----------SEKQYGRI---------------T 367
Query: 371 HLENTHSCHPMSG-ECACKPGWSGLYCNETCSPGFYGEACQQICS---CQNGADCDSVTG 426
L ++ S H SG C C+PG++G++C E + CS CQNG C+++ G
Sbjct: 368 GLPSSFSYHEASGYVCICQPGFTGIHCEEDVNE----------CSSNPCQNGGTCENLPG 417
Query: 427 KCTCAPGFK--------GIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWH 478
TC F G DCS + C+ + C N+ C P + G H
Sbjct: 418 NYTCHCPFDNLSRTFYGGRDCSDIL------LGCTHQ-QCLNNGTCIP-----HFQDGQH 465
Query: 479 GVDCSIRCPSGTWGFGCNL 497
G C CPSG G C +
Sbjct: 466 GFSC--LCPSGYTGSLCEI 482
Score = 98.2 bits (243), Expect = 4e-20
Identities = 72/219 (32%), Positives = 89/219 (40%), Gaps = 42/219 (19%)
Query: 154 CKNGALCNPITGACHCAA--GFRGWRCEDRCEQGTYGNDC-HQRCQCQNGATCDHVTGEC 210
C +G C I + HC+ G+ G CE ++ + N C H C + A C
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDE-CFSNPCIHGNCSDRVAAY------HC 1200
Query: 211 RCPPGYTGAFCE---DLCPPGKHGPQCEQRCPCQNGGVC-HHVTG-ECSCPSGWMGTVCG 265
C PGYTG CE D C Q C NG C H G C C + G C
Sbjct: 1201 TCEPGYTGVNCEVDIDNC----------QSHQCANGATCISHTNGYSCLCFGNFTGKFCR 1250
Query: 266 QPCPEGRFGKNCSQECQCHNGGTCDAATGQ--CHCSPGYTGERCQ---DECPVGTYGVLC 320
Q N C+NGG C + C C PG+TGE C+ DEC
Sbjct: 1251 QSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECA-------- 1302
Query: 321 AETCQCVNGGKCYHVSGA--CLCEAGFAGERCEARLCPE 357
+ CVNGG C + CLC+ FAGERCE L +
Sbjct: 1303 --SDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDLADD 1339
Score = 85.1 bits (209), Expect = 3e-16
Identities = 64/220 (29%), Positives = 86/220 (39%), Gaps = 53/220 (24%)
Query: 239 PCQNGGVCHHVTGE--CSCPSGWMGTVC--------GQPCPEGRFGKNCSQECQCHNGGT 288
PC +GG C + CSCP GW G C PC G NCS ++
Sbjct: 1147 PCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG----NCSDRVAAYH--- 1199
Query: 289 CDAATGQCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCY-HVSG-ACLCEA 343
C C PGYTG C+ D C ++ QC NG C H +G +CLC
Sbjct: 1200 -------CTCEPGYTGVNCEVDIDNC----------QSHQCANGATCISHTNGYSCLCFG 1242
Query: 344 GFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE--CACKPGWSGLYCNETCS 401
F G+ C P + G +++ N +C E C C+PG++G +C +
Sbjct: 1243 NFTGKFCRQSRLPSTVCG---NEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI- 1298
Query: 402 PGFYGEACQQICSCQNGADCDSVTGK--CTCAPGFKGIDC 439
+ C C NG C + K C C F G C
Sbjct: 1299 -----DECAS-DPCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
Score = 85.1 bits (209), Expect = 3e-16
Identities = 58/173 (33%), Positives = 76/173 (43%), Gaps = 26/173 (15%)
Query: 103 EMCVPHC-ADKCVHGRC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGA 158
E+ + C ++ C+HG C +A C CEPG+ G NC D +C S QC NGA
Sbjct: 1175 ELNIDECFSNPCIHGNCSDRVAAYHCTCEPGYTGVNCEVDID------NCQSH-QCANGA 1227
Query: 159 LCNPITG--ACHCAAGFRGWRC-EDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCP 213
C T +C C F G C + R GN+ C NG C E C C
Sbjct: 1228 TCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNE-KTNLTCYNGGNCTEFQTELKCMCR 1286
Query: 214 PGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVC 264
PG+TG +CE K +C PC NGG+C + +C C + G C
Sbjct: 1287 PGFTGEWCE------KDIDECASD-PCVNGGLCQDLLNKFQCLCDVAFAGERC 1332
Score = 82.0 bits (201), Expect = 3e-15
Identities = 64/212 (30%), Positives = 79/212 (37%), Gaps = 36/212 (16%)
Query: 110 ADKCVHG-RC---IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITG 165
++ C+HG C + C C GW G +C D P C + A
Sbjct: 1145 SNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY------ 1198
Query: 166 ACHCAAGFRGWRCE---DRCEQGTYGNDCHQRCQCQNGATC-DHVTG-ECRCPPGYTGAF 220
C C G+ G CE D C Q QC NGATC H G C C +TG F
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNC----------QSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
Query: 221 CEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE--CSCPSGWMGTVCGQPCPEGRFGKNCS 278
C P + C NGG C E C C G+ G C + E C+
Sbjct: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE------CA 1302
Query: 279 QECQCHNGGTCDAATG--QCHCSPGYTGERCQ 308
+ C NGG C QC C + GERC+
Sbjct: 1303 SD-PCVNGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 77.8 bits (190), Expect = 5e-14
Identities = 60/206 (29%), Positives = 78/206 (37%), Gaps = 32/206 (15%)
Query: 599 ICECAPGFRGTTCQRI-------CSPGFYGHRCSQTCPQCVHSSGPCHH-------ITGL 644
+C P G C+ I C G+ G C +C S PC H
Sbjct: 1142 VCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECF--SNPCIHGNCSDRVAAYH 1199
Query: 645 CDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCP 704
C C PG+TG C EV CA TC ++ SC C+ + G C Q
Sbjct: 1200 CTCEPGYTGVNC-EVDIDNCQSHQCANGATCISHTN----GYSCLCFGNFTGKFCRQSRL 1254
Query: 705 PAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQRCPLGFYGKDCALICQCQ 762
P+ N C+NG C+ + E C C PG+TG +C + +CA C
Sbjct: 1255 PSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI------DECA-SDPCV 1307
Query: 763 NGADCDHISG--QCTCRTGFMGRHCE 786
NG C + QC C F G CE
Sbjct: 1308 NGGLCQDLLNKFQCLCDVAFAGERCE 1333
Score = 73.9 bits (180), Expect = 8e-13
Identities = 77/286 (26%), Positives = 120/286 (41%), Gaps = 64/286 (22%)
Query: 632 VHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCA-GICTCTNN----GTCNPIDR 686
V +S PC H G C+ + ++ C+ CP G GK+C I C +N G C+ DR
Sbjct: 1142 VCNSNPCLH-GGNCEDI--YSSYHCS--CPLGWSGKHCELNIDECFSNPCIHGNCS--DR 1194
Query: 687 ----SCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDG--ECKCTPGWTGL 740
C C PG+ G +C NC + C NGA C ++ C C +TG
Sbjct: 1195 VAAYHCTCEPGYTGVNCEVDID------NC-QSHQCANGATCISHTNGYSCLCFGNFTGK 1247
Query: 741 YCTQ-RCPLGFYGKDCALICQCQNGADCDHISGQ--CTCRTGFMGRHCEQ---KCPSGTY 794
+C Q R P G + + C NG +C + C CR GF G CE+ +C S
Sbjct: 1248 FCRQSRLPSTVCGNEKTNLT-CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASD-- 1304
Query: 795 GYGCRQICDCLNNSTCDHITG--TCYCSPGWKGARCDQAGVIIVGNLNSLSRTSTALPAD 852
C+N C + C C + G RC+ V + +L S T+
Sbjct: 1305 --------PCVNGGLCQDLLNKFQCLCDVAFAGERCE---VDLADDLISDIFTT------ 1347
Query: 853 SYQIGAIAGIIILVLVVLFLLALFIIYRHKQKGKESSMPAVTYTPA 898
IG++ ++L+L++ + ++ + +G TY+P+
Sbjct: 1348 ---IGSVTVALLLILLLAIVASVVTSNKRATQG--------TYSPS 1382
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/221 (28%), Positives = 79/221 (35%), Gaps = 34/221 (15%)
Query: 532 GTYGLNCAERCDCSHADGCHP--TTGHCRCLPGWSGVHCDSVCAEGRWGPNC-SLPCYCK 588
G LN C H C ++ HC C GWSG HC+ E C S PC
Sbjct: 1136 GCLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDE------CFSNPCIHG 1189
Query: 589 NGASCSPDDGI--CECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCD 646
N CS C C PG+ G C+ + H+C+ H++G C
Sbjct: 1190 N---CSDRVAAYHCTCEPGYTGVNCE-VDIDNCQSHQCANGATCISHTNGYS------CL 1239
Query: 647 CLPGFTGALCNEV-CPSGRFGKNCAGICTCTNNGTCNPI--DRSCQCYPGWIGSDCSQPC 703
C FTG C + PS G + TC N G C + C C PG+ G C +
Sbjct: 1240 CFGNFTGKFCRQSRLPSTVCGNEKTNL-TCYNGGNCTEFQTELKCMCRPGFTGEWCEKDI 1298
Query: 704 PPAHWGPNCIHTCNCHNGAFCS--AYDGECKCTPGWTGLYC 742
P C NG C +C C + G C
Sbjct: 1299 DECASDP-------CVNGGLCQDLLNKFQCLCDVAFAGERC 1332
Score = 69.3 bits (168), Expect = 2e-11
Identities = 59/217 (27%), Positives = 84/217 (38%), Gaps = 37/217 (17%)
Query: 326 CVNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSG 383
C++GG C + + C C G++G+ CE + +C PC + S +
Sbjct: 1148 CLHGGNCEDIYSSYHCSCPLGWSGKHCELNID-------ECFSN-PC-IHGNCSDRVAAY 1198
Query: 384 ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG--KCTCAPGFKGIDCST 441
C C+PG++G+ C + CQ C NGA C S T C C F G C
Sbjct: 1199 HCTCEPGYTGVNCEVDI------DNCQSH-QCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Query: 442 PCPLGTYGINCSSRCGCKNDAVCSP--VDGSCTCKAGWHGVDCSI---RCPSGTWGFGCN 496
T N + C N C+ + C C+ G+ G C C S
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDP------ 1305
Query: 497 LTCQCLNGGACNTLDGT--CTCAPGWRGEKCELPCQD 531
C+NGG C L C C + GE+CE+ D
Sbjct: 1306 ----CVNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 68.9 bits (167), Expect = 3e-11
Identities = 61/196 (31%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 382 SGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCST 441
S C+C GWSG +C F CS + A CTC PG+ G++C
Sbjct: 1160 SYHCSCPLGWSGKHCELNIDECFSNPCIHGNCSDRVAAY------HCTCEPGYTGVNCEV 1213
Query: 442 PCPLGTYGINCSSRCGCKNDAVC-SPVDG-SCTCKAGWHGVDC-SIRCPSGTWG-FGCNL 497
NC S C N A C S +G SC C + G C R PS G NL
Sbjct: 1214 DID------NCQSH-QCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKTNL 1266
Query: 498 TCQCLNGGACNTL--DGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG 555
T C NGG C + C C PG+ GE CE + CA C + C
Sbjct: 1267 T--CYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDE------CASD-PCVNGGLCQDLLN 1317
Query: 556 --HCRCLPGWSGVHCD 569
C C ++G C+
Sbjct: 1318 KFQCLCDVAFAGERCE 1333
Score = 66.2 bits (160), Expect = 2e-10
Identities = 61/213 (28%), Positives = 79/213 (37%), Gaps = 53/213 (24%)
Query: 90 RKSQCCPGFYESGEMC---VPHCADKCVHGRCIAPN-----TCQCEPGWGGTNCSSACDG 141
R S C G +G C +P C K H + TC C PG+ G C +
Sbjct: 283 RYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNE 342
Query: 142 DHWGPHCTSRCQC---KNGALCNPITG-------------ACHCAAGFRGWRCEDRCEQG 185
+ P C S +C + ITG C C GF G CE+
Sbjct: 343 CNSNP-CQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDV--- 398
Query: 186 TYGNDCHQRCQCQNGATCDHVTGE--CRCP------PGYTGAFCEDLCPPGKHGPQCEQR 237
N+C CQNG TC+++ G C CP Y G C D+ H
Sbjct: 399 ---NECSSN-PCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQ------ 448
Query: 238 CPCQNGGVC--HHVTGE----CSCPSGWMGTVC 264
C N G C H G+ C CPSG+ G++C
Sbjct: 449 -QCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLC 480
Score = 39.7 bits (91), Expect = 0.016
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 9/66 (13%)
Query: 239 PCQNGGVCHHVTGE--CSCPSGWMGTVCGQ-------PCPEGRFGKNCSQECQCHNGGTC 289
PC NGGVCH + CSCP+ G C + PCP G + Q +C
Sbjct: 895 PCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFECIANAVF 954
Query: 290 DAATGQ 295
+ +GQ
Sbjct: 955 NGQSGQ 960
Score = 36.2 bits (82), Expect = 0.18
Identities = 25/86 (29%), Positives = 32/86 (37%), Gaps = 18/86 (20%)
Query: 270 EGRFGKNCSQECQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAET-----C 324
+G G N + CHNGG C + CS CP T G C E
Sbjct: 883 QGCAGDNSCKSNPCHNGGVCHSRWDDFSCS-----------CPALTSGKACEEVQWCGFS 931
Query: 325 QCVNGGKCYHV--SGACLCEAGFAGE 348
C +G +C V C+ A F G+
Sbjct: 932 PCPHGAQCQPVLQGFECIANAVFNGQ 957
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.500
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,489,741
Number of Sequences: 37866
Number of extensions: 3513028
Number of successful extensions: 28614
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 141
Number of HSP's successfully gapped in prelim test: 448
Number of HSP's that attempted gapping in prelim test: 8465
Number of HSP's gapped (non-prelim): 5705
length of query: 1140
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1027
effective length of database: 13,968,660
effective search space: 14345813820
effective search space used: 14345813820
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.