BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] (716 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 1410 0.0 gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 1368 0.0 gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] 354 2e-97 gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] 312 6e-85 gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] 182 7e-46 gi|6005942 valosin-containing protein [Homo sapiens] 178 1e-44 gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 173 4e-43 gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 167 4e-41 gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 160 3e-39 gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 160 4e-39 gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 157 4e-38 gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens] 156 6e-38 gi|157671927 spermatogenesis associated 5 [Homo sapiens] 156 6e-38 gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 154 3e-37 gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 154 3e-37 gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ... 152 1e-36 gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi... 152 1e-36 gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] 152 1e-36 gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 146 7e-35 gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 145 1e-34 gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 145 2e-34 gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 145 2e-34 gi|4505725 peroxin1 [Homo sapiens] 142 1e-33 gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] 132 9e-31 gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens] 128 2e-29 gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 127 3e-29 gi|40806170 spastin isoform 2 [Homo sapiens] 126 8e-29 gi|11875211 spastin isoform 1 [Homo sapiens] 126 8e-29 gi|31742536 fidgetin-like 1 [Homo sapiens] 125 1e-28 gi|112789543 fidgetin-like 1 [Homo sapiens] 125 1e-28 >gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] Length = 716 Score = 1410 bits (3650), Expect = 0.0 Identities = 716/716 (100%), Positives = 716/716 (100%) Query: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN 60 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN Sbjct: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSEPSLN 60 Query: 61 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR 120 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR Sbjct: 61 LRDLGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLR 120 Query: 121 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK 180 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK Sbjct: 121 SSCLYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVK 180 Query: 181 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL 240 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL Sbjct: 181 GFLLRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLIL 240 Query: 241 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF 300 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF Sbjct: 241 FVLLLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF 300 Query: 301 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA 360 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA Sbjct: 301 LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGA 360 Query: 361 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI 420 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI Sbjct: 361 SRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVI 420 Query: 421 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG 480 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG Sbjct: 421 IIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARG 480 Query: 481 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA 540 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA Sbjct: 481 TVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITA 540 Query: 541 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG 600 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG Sbjct: 541 YHESGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGG 600 Query: 601 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI 660 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI Sbjct: 601 RVAEELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAI 660 Query: 661 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 716 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR Sbjct: 661 EQEIRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 716 >gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] Length = 773 Score = 1368 bits (3541), Expect = 0.0 Identities = 710/773 (91%), Positives = 712/773 (92%), Gaps = 57/773 (7%) Query: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE---- 56 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSE Sbjct: 1 MFSLSSTVQPQVTVPLSHLINAFHTPKNTSVSLSGVSVSQNQHRDVVPEHEAPSSECMFS 60 Query: 57 ---PSLNLRDLG------------------------------------------------ 65 LN+ +G Sbjct: 61 DFLTKLNIVSIGKGKIFEGYRSMFMEPAKRMKKSLDTTDNWHIRPEPFSLSIPPSLNLRD 120 Query: 66 --LSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 123 LSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC Sbjct: 121 LGLSELKIGQIDQLVENLLPGFCKGKNISSHWHTSHVSAQSFFENKYGNLDIFSTLRSSC 180 Query: 124 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 183 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL Sbjct: 181 LYRHHSRALQSICSDLQYWPVFIQSRGFKTLKSRTRRLQSTSERLAETQNIAPSFVKGFL 240 Query: 184 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 243 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL Sbjct: 241 LRDRGSDVESLDKLMKTKNIPEAHQDAFKTGFAEGFLKAQALTQKTNDSLRRTRLILFVL 300 Query: 244 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 303 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN Sbjct: 301 LLFGIYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKN 360 Query: 304 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 363 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI Sbjct: 361 PQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 420 Query: 364 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 423 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG Sbjct: 421 RNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIG 480 Query: 424 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 483 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG Sbjct: 481 ATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVG 540 Query: 484 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 543 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE Sbjct: 541 FSGAELENLVNQAALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHE 600 Query: 544 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 603 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA Sbjct: 601 SGHAIIAYYTKDAMPINKATIMPRGPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVA 660 Query: 604 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 663 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE Sbjct: 661 EELIFGTDHITTGASSDFDNATKIAKRMVTKFGMSEKLGVMTYSDTGKLSPETQSAIEQE 720 Query: 664 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 716 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR Sbjct: 721 IRILLRDSYERAKHILKTHAKEHKNLAEALLTYETLDAKEIQIVLEGKKLEVR 773 >gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] Length = 797 Score = 354 bits (908), Expect = 2e-97 Identities = 192/441 (43%), Positives = 280/441 (63%), Gaps = 17/441 (3%) Query: 278 NVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 337 +V F+ V G EEAK E+ E V FLKNP+++ LG K+PKG +L GPPGTGKTLLA+A AG Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363 Query: 338 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 397 EA+VPF SGSEF EMFVGVG +R+R+LF A+ NAPC++FIDE+D+VG KR Sbjct: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423 Query: 398 YSRQ--TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 455 S Q T+NQLL EMDGF V+I+ TN P+ LD AL+RPGRFD Q+ + PD+KGR Sbjct: 424 QSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483 Query: 456 TEILKWYLNKIKFDQSVDPEIIARG----TVGFSGAELENLVNQAALKAAVDGKEMVTMK 511 I K +L +K D +++ + +AR T GFSGA++ N+ N+AAL AA + + K Sbjct: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543 Query: 512 ELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTL 571 E + ++++ G E+++ + + K AYHE+GHA+ +Y + A P+ K +I+PRG L Sbjct: 544 HFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGL 603 Query: 572 GHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRM 631 G+ LP+ +++ T+ QLL +M +++GGR +EE+ FG ITTGA D T+ A Sbjct: 604 GYAQYLPK-EQYLYTKEQLLDRMCMTLGGRASEEIFFG--RITTGAQDDLRKVTQSAYAQ 660 Query: 632 VTKFGMSEKLGVMTYSDTGK--------LSPETQSAIEQEIRILLRDSYERAKHILKTHA 683 + +FGM+EK+G +++ + S T I+ E+RIL+ D+Y+R +L Sbjct: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720 Query: 684 KEHKNLAEALLTYETLDAKEI 704 + + +A LL E LD ++ Sbjct: 721 ADVEKVALLLLEKEVLDKNDM 741 >gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] Length = 795 Score = 312 bits (800), Expect = 6e-85 Identities = 175/454 (38%), Positives = 279/454 (61%), Gaps = 20/454 (4%) Query: 271 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 330 VD K V+F+ V G+ EAK E++E V++LK+P++F LG K+PKG LL+GPPG GKTL Sbjct: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357 Query: 331 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 390 LA+AVA EA VPF +G EF E+ G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR Sbjct: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417 Query: 391 IESPMHPYS----RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVT 446 + M +S QT+NQLL EMDG + VI++ +TN + LD AL+RPGR D V Sbjct: 418 -STTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVF 476 Query: 447 VPRPDVKGRTEILKWYLNKIKFDQSVD--PEIIARGTVGFSGAELENLVNQAALKAAVDG 504 + P ++ R EI + +L +K QS + +A T GFSGA++ N+ N+AAL AA +G Sbjct: 477 IDLPTLQERREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREG 536 Query: 505 KEMVTMKELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATI 564 V E++ +++L G ++S + + + + A+HESGHA++ + + + K +I Sbjct: 537 HTSVHTLNFEYAVERVLAGTAKKSKILSKEEQKVVAFHESGHALVGWMLEHTEAVMKVSI 596 Query: 565 MPR-GPTLGHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDN 623 PR LG +LP D+ T+ QL +M +++GGR +E L F + +T+GA D Sbjct: 597 TPRTNAALGFAQMLP-RDQHLFTKEQLFERMCMALGGRASEALSF--NEVTSGAQDDLRK 653 Query: 624 ATKIAKRMVTKFGMSEKLGVMTYSDTGK---------LSPETQSAIEQEIRILLRDSYER 674 T+IA MV +FGM+ +G +++ + + S Q ++ E R+L+ +Y Sbjct: 654 VTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRRPFSQGLQQMMDHEARLLVAKAYRH 713 Query: 675 AKHILKTHAKEHKNLAEALLTYETLDAKEIQIVL 708 + +L+ + + + LA ALL E ++ ++I+ ++ Sbjct: 714 TEKVLQDNLDKLQALANALLEKEVINYEDIEALI 747 >gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] Length = 406 Score = 182 bits (463), Expect = 7e-46 Identities = 102/275 (37%), Positives = 168/275 (61%), Gaps = 10/275 (3%) Query: 267 LDSAVDPV-------QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGI 318 L + VDP+ ++ + T+E + G+++ +E++EV+E +K+P+ F LG PKG+ Sbjct: 127 LPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGV 186 Query: 319 LLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVI 378 LL GPPGTGKTLLARAVA D F SGSE + F+G GA +R LF A+ +AP +I Sbjct: 187 LLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSII 246 Query: 379 FIDELDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALI 436 F+DE+DS+G R+E S ++T+ +LL ++DGF+ + + +I ATN + LD+AL+ Sbjct: 247 FMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALL 306 Query: 437 RPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQA 496 RPGR D ++ P P+ + R +ILK + K+ + ++ IA G SGAE++ + +A Sbjct: 307 RPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEA 366 Query: 497 ALKAAVDGKEMVTMKELEFSKDKILMGPERRSVEI 531 + A + + VT ++ E + K++ +++ I Sbjct: 367 GMYALRERRVHVTQEDFEMAVAKVMQKDSEKNMSI 401 >gi|6005942 valosin-containing protein [Homo sapiens] Length = 806 Score = 178 bits (452), Expect = 1e-44 Identities = 102/245 (41%), Positives = 142/245 (57%), Gaps = 5/245 (2%) Query: 274 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 332 V++ VT+E + G+E+ K+ELQE+V++ +++P KF G KG+L GPPG GKTLLA Sbjct: 469 VEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLA 528 Query: 333 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVG---GK 389 +A+A E F G E M+ G + +R +F +A+ APCV+F DELDS+ G Sbjct: 529 KAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGG 588 Query: 390 RIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 449 I R INQ+L EMDG + V IIGATN P+ +D A++RPGR D + +P Sbjct: 589 NIGDGGGAADR-VINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPL 647 Query: 450 PDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVT 509 PD K R ILK L K + VD E +A+ T GFSGA+L + +A A + E Sbjct: 648 PDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEI 707 Query: 510 MKELE 514 +E E Sbjct: 708 RRERE 712 Score = 173 bits (438), Expect = 6e-43 Identities = 97/238 (40%), Positives = 141/238 (59%), Gaps = 2/238 (0%) Query: 276 MKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 334 + V ++ + G + +++E+VE L++P F +G K P+GILL GPPGTGKTL+ARA Sbjct: 198 LNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARA 257 Query: 335 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 394 VA E F+ +G E G S +R F EA+ NAP +IFIDELD++ KR E Sbjct: 258 VANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR-EKT 316 Query: 395 MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454 R+ ++QLL MDG K VI++ ATN P ++D AL R GRFD +V + PD G Sbjct: 317 HGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376 Query: 455 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 512 R EIL+ + +K VD E +A T G GA+L L ++AAL+A +++ +++ Sbjct: 377 RLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLED 434 >gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] Length = 433 Score = 173 bits (439), Expect = 4e-43 Identities = 96/261 (36%), Positives = 158/261 (60%), Gaps = 6/261 (2%) Query: 267 LDSAVDPVQMK---NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVG 322 +D V +Q++ +VT+ V G +E ++L+EVVE L +P++F LG + PKG+LL G Sbjct: 157 IDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFG 216 Query: 323 PPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDE 382 PPGTGKTL ARAVA D F GSE + +VG GA +R LF A+ C+IF DE Sbjct: 217 PPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDE 276 Query: 383 LDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGR 440 +D++GG R + + ++T+ +L+ ++DGF P + ++ ATN P+ LD AL+RPGR Sbjct: 277 IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGR 336 Query: 441 FDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 D ++ PD++GRT I K + + ++ + E++AR +GAE+ ++ +A + A Sbjct: 337 LDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFA 396 Query: 501 AVDGKEMVTMKELEFSKDKIL 521 +++ T K+ + +K++ Sbjct: 397 IRARRKIATEKDFLEAVNKVI 417 >gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] Length = 403 Score = 167 bits (422), Expect = 4e-41 Identities = 93/238 (39%), Positives = 142/238 (59%), Gaps = 3/238 (1%) Query: 278 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVA 336 NV++ + G+ E +EL+EV+E L NP+ F +G PKG LL GPPGTGKTLLARAVA Sbjct: 143 NVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVA 202 Query: 337 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE--SP 394 + D F S + ++G A IR +F A+ + PC+IF+DE+D++GG+R + Sbjct: 203 SQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTS 262 Query: 395 MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454 ++T+ +LL +MDGF V +I ATN P+ LD AL+RPGR D ++ + P+ + Sbjct: 263 ADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQA 322 Query: 455 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 512 R +ILK + I +D E I + + GF+GA+L N+ +A + A + V ++ Sbjct: 323 RLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQED 380 >gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] Length = 440 Score = 160 bits (406), Expect = 3e-39 Identities = 90/245 (36%), Positives = 145/245 (59%), Gaps = 3/245 (1%) Query: 280 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 338 T+ + G++ QE++E VE L +P+ + +G K PKG++L GPPGTGKTLLA+AVA + Sbjct: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242 Query: 339 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 396 F GSE + ++G G +R LFR A+ +AP ++FIDE+D++G KR +S Sbjct: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGE 302 Query: 397 PYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRT 456 ++T+ +LL ++DGF V +I ATN E LD ALIRPGR D ++ P PD K + Sbjct: 303 REIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKK 362 Query: 457 EILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELEFS 516 I + + +++ V + + SGA+++ + +A L A + + VT ++ + S Sbjct: 363 RIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKS 422 Query: 517 KDKIL 521 K+ +L Sbjct: 423 KENVL 427 >gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] Length = 439 Score = 160 bits (405), Expect = 4e-39 Identities = 97/271 (35%), Positives = 155/271 (57%), Gaps = 7/271 (2%) Query: 248 IYGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNP--- 304 + G+ K+ +L + T DS V +++ E + +++QE+VE + P Sbjct: 150 LVGVNKDSYLILE-TLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNH 208 Query: 305 -QKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRI 363 +KF LG + PKG+L+ GPPGTGKTLLARA A + F +G + +MF+G GA + Sbjct: 209 KEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLV 268 Query: 364 RNLFREAKANAPCVIFIDELDSVGGKRIESPM--HPYSRQTINQLLAEMDGFKPNEGVII 421 R+ F AK AP +IFIDELD++G KR +S ++T+ +LL ++DGF+PN V + Sbjct: 269 RDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKV 328 Query: 422 IGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGT 481 I ATN + LD AL+R GR D ++ P P+ + R I++ + K+ V+ E +AR T Sbjct: 329 IAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCT 388 Query: 482 VGFSGAELENLVNQAALKAAVDGKEMVTMKE 512 F+GA+ + + +A + A G +T ++ Sbjct: 389 DDFNGAQCKAVCVEAGMIALRRGATELTHED 419 >gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] Length = 753 Score = 157 bits (396), Expect = 4e-38 Identities = 103/279 (36%), Positives = 149/279 (53%), Gaps = 28/279 (10%) Query: 261 FRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGIL 319 FR+ GL + +K V +E + G+E+ K +L++ +E+ LK P +F +G PKG+L Sbjct: 449 FRSVIGL------MDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVL 502 Query: 320 LVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIF 379 L GPPG KT L RA+A F SG++ FVG + +FR+A+A+ P ++F Sbjct: 503 LYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILF 562 Query: 380 IDELDSVGGKRIESPMH-PYSRQTINQLLAEMDG-----------------FKP--NEGV 419 +DE+DS+ G R S + ++ LL E+DG F+ N V Sbjct: 563 LDEIDSILGARSASKTGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSV 622 Query: 420 IIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIAR 479 +II ATN P+ LD AL+RPGR D + +P PD KGR ILK + V E +A Sbjct: 623 MIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLAA 682 Query: 480 GTVGFSGAELENLVNQAALKAAVD-GKEMVTMKELEFSK 517 T FSGA+L NL +AAL A + G + T+K+ F K Sbjct: 683 ETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLK 721 Score = 140 bits (354), Expect = 3e-33 Identities = 85/225 (37%), Positives = 127/225 (56%), Gaps = 7/225 (3%) Query: 286 GVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFY 344 G+ EA L+E++ L+ P+ T LG +P+G+LL GPPG GKT L RAVA EA Sbjct: 204 GLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAELL 263 Query: 345 YASGSEFDEMFVGVGASRIRNLF---REAKANAPCVIFIDELDSVGGKRIESPMHPYSRQ 401 S G +R +F RE + P ++F+DE+D++ +R P SR Sbjct: 264 AVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR--GSRAPESR- 320 Query: 402 TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKW 461 + Q+L +DG + V+++GATN P+ALD AL RPGRFD +V + P +K R EIL+ Sbjct: 321 VVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKEILQV 380 Query: 462 YLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKE 506 +K+ VD ++A TVG+ GA+L L +AA+ A + ++ Sbjct: 381 ITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEK 425 >gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens] Length = 489 Score = 156 bits (395), Expect = 6e-38 Identities = 80/146 (54%), Positives = 109/146 (74%), Gaps = 5/146 (3%) Query: 271 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 330 VD K V+F+ V G+ EAK E++E V++LK+P++F LG K+PKG LL+GPPG GKTL Sbjct: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357 Query: 331 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 390 LA+AVA EA VPF +G EF E+ G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR Sbjct: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417 Query: 391 IESPMHPYS----RQTINQLLAEMDG 412 + M +S QT+NQLL EMDG Sbjct: 418 -STTMSGFSNTEEEQTLNQLLVEMDG 442 >gi|157671927 spermatogenesis associated 5 [Homo sapiens] Length = 893 Score = 156 bits (395), Expect = 6e-38 Identities = 88/229 (38%), Positives = 135/229 (58%), Gaps = 2/229 (0%) Query: 274 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 332 + + NV++ + G+E K +L++ VE+ LK+P+ F +G + PKG+LL GPPG KT++A Sbjct: 619 IDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIA 678 Query: 333 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 392 +A+A E+ + F G E +VG +R FR+A+A AP +IF DELD++ +R Sbjct: 679 KALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGS 738 Query: 393 S-PMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 S + + + QLL EMDG + + V I+ ATN P+ +D AL+RPGR D + VP PD Sbjct: 739 SLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPD 798 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 R EI K + + VD + + T +SGAE+ + +AAL A Sbjct: 799 AATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLA 847 Score = 144 bits (362), Expect = 4e-34 Identities = 87/228 (38%), Positives = 134/228 (58%), Gaps = 8/228 (3%) Query: 279 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 337 VT++ + G+ + ++E++E LK P+ F G P+G+LL GPPGTGKT++ARAVA Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVAN 409 Query: 338 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 397 E +G E F G +++R +F EA P +IFIDELD++ KR E + Sbjct: 410 EVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKR-EGAQNE 468 Query: 398 YSRQTINQLLAEMDGF--KPNEG-VIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454 ++ + LL MDG + +EG V+++GATN P ALD AL RPGRFD ++ + P+ + Sbjct: 469 VEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQD 528 Query: 455 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKA 500 R +IL+ L ++ + E+ +A G+ GA+L+ L N+A L A Sbjct: 529 RLDILQKLLRRVP-HLLTEAELLQLANSAHGYVGADLKVLCNEAGLCA 575 >gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] Length = 750 Score = 154 bits (389), Expect = 3e-37 Identities = 91/229 (39%), Positives = 133/229 (58%), Gaps = 4/229 (1%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 334 Q+ NV FE V G + +E+ +++ +++P+ + LG P+G+LL GPPG GKTLLA A Sbjct: 152 QISNVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHA 211 Query: 335 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 394 +AGE D+P + E G ++R LF +A +NAPC+IFIDE+D++ KR E Sbjct: 212 IAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR-EVA 270 Query: 395 MHPYSRQTINQLLAEMDGFK---PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 R+ + QLL MD V++IGATN P++LD AL R GRFD ++ + PD Sbjct: 271 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 330 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 R IL+ K++ Q+ D +A T GF GA+L L +AA+ A Sbjct: 331 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCA 379 Score = 149 bits (375), Expect = 1e-35 Identities = 92/234 (39%), Positives = 136/234 (58%), Gaps = 9/234 (3%) Query: 274 VQMKNVTFEHVKGVEEAKQEL-QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 332 V + NVT+ + +E+ ++EL ++ ++NP +F LG P G+LL GPPG GKTLLA Sbjct: 467 VTVPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLA 526 Query: 333 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 392 +AVA E+ + F G E M+VG +R +F+ AK +APCVIF DE+D++ +R + Sbjct: 527 KAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSD 586 Query: 393 SPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDV 452 S + +NQLL EMDG + + V I+ ATN P+ +D A++RPGR D + V P Sbjct: 587 RETGA-SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 645 Query: 453 KGRTEILKWYL---NKIKFDQSVDPEIIARGTVG---FSGAELENLVNQAALKA 500 R ILK K D V+ E IA G + ++GA+L LV +A++ A Sbjct: 646 ADRLAILKTITKNGTKPPLDADVNLEAIA-GDLRCDCYTGADLSALVREASICA 698 >gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] Length = 856 Score = 154 bits (389), Expect = 3e-37 Identities = 91/229 (39%), Positives = 133/229 (58%), Gaps = 4/229 (1%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARA 334 Q+ NV FE V G + +E+ +++ +++P+ + LG P+G+LL GPPG GKTLLA A Sbjct: 258 QISNVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHA 317 Query: 335 VAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESP 394 +AGE D+P + E G ++R LF +A +NAPC+IFIDE+D++ KR E Sbjct: 318 IAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR-EVA 376 Query: 395 MHPYSRQTINQLLAEMDGFK---PNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 R+ + QLL MD V++IGATN P++LD AL R GRFD ++ + PD Sbjct: 377 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 436 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 R IL+ K++ Q+ D +A T GF GA+L L +AA+ A Sbjct: 437 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCA 485 Score = 149 bits (375), Expect = 1e-35 Identities = 92/234 (39%), Positives = 136/234 (58%), Gaps = 9/234 (3%) Query: 274 VQMKNVTFEHVKGVEEAKQEL-QEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLA 332 V + NVT+ + +E+ ++EL ++ ++NP +F LG P G+LL GPPG GKTLLA Sbjct: 573 VTVPNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLA 632 Query: 333 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 392 +AVA E+ + F G E M+VG +R +F+ AK +APCVIF DE+D++ +R + Sbjct: 633 KAVANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSD 692 Query: 393 SPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDV 452 S + +NQLL EMDG + + V I+ ATN P+ +D A++RPGR D + V P Sbjct: 693 RETGA-SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPP 751 Query: 453 KGRTEILKWYL---NKIKFDQSVDPEIIARGTVG---FSGAELENLVNQAALKA 500 R ILK K D V+ E IA G + ++GA+L LV +A++ A Sbjct: 752 ADRLAILKTITKNGTKPPLDADVNLEAIA-GDLRCDCYTGADLSALVREASICA 804 >gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4 [Homo sapiens] Length = 414 Score = 152 bits (383), Expect = 1e-36 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 333 Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+ Sbjct: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Query: 334 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 393 AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++ Sbjct: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 Query: 394 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 ++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD Sbjct: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 511 + + I +K+ + VD E SGA++ ++ ++ + A + + +V K Sbjct: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393 Query: 512 ELEFSKDKILMGPER 526 + E + ++ E+ Sbjct: 394 DFEKAYKTVIKKDEQ 408 >gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapiens] Length = 387 Score = 152 bits (383), Expect = 1e-36 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 333 Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+ Sbjct: 127 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 186 Query: 334 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 393 AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++ Sbjct: 187 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 246 Query: 394 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 ++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD Sbjct: 247 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 306 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 511 + + I +K+ + VD E SGA++ ++ ++ + A + + +V K Sbjct: 307 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 366 Query: 512 ELEFSKDKILMGPER 526 + E + ++ E+ Sbjct: 367 DFEKAYKTVIKKDEQ 381 >gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] Length = 418 Score = 152 bits (383), Expect = 1e-36 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 333 Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+ Sbjct: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217 Query: 334 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 393 AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++ Sbjct: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277 Query: 394 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 ++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD Sbjct: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337 Query: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 511 + + I +K+ + VD E SGA++ ++ ++ + A + + +V K Sbjct: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397 Query: 512 ELEFSKDKILMGPER 526 + E + ++ E+ Sbjct: 398 DFEKAYKTVIKKDEQ 412 >gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] Length = 980 Score = 146 bits (368), Expect = 7e-35 Identities = 102/282 (36%), Positives = 149/282 (52%), Gaps = 19/282 (6%) Query: 249 YGLLKNPFLSVRFRTTTGLDSAVDPVQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKF 307 + LL F + T AV ++ +V++ V G++E K+E+ E ++ L++P+ Sbjct: 672 FPLLAEDFGQALEQLQTAHSQAVGAPKIPSVSWHDVGGLQEVKKEILETIQLPLEHPELL 731 Query: 308 TILGGKLPKGILLVGPPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLF 367 ++ G G+LL GPPGTGKTLLA+AVA E + F G E M+VG +R +F Sbjct: 732 SL--GLRRSGLLLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVF 789 Query: 368 REAKANAPCVIFIDELDSVGGKRIES-PMHPYSRQTINQLLAEMDGFKPNEGVIIIGATN 426 A+A APC+IF DELDS+ R S + ++QLLAE+DG + V +IGATN Sbjct: 790 ARARAAAPCIIFFDELDSLAPSRGRSGDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATN 849 Query: 427 FPEALDNALIRPGRFDMQVTV-PRPDVKGRTEILKWYLNKIKFDQSVD-PEIIARGTVGF 484 P+ LD AL+RPGRFD V V D + +L K K + SV ++ Sbjct: 850 RPDLLDPALLRPGRFDKLVFVGANEDRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQL 909 Query: 485 SGAELENLVNQ---AALKAAVDGKE----------MVTMKEL 513 +GA+L +L + AALK V E M+TM++L Sbjct: 910 TGADLYSLCSDAMTAALKRRVHDLEEGLEPGSSALMLTMEDL 951 Score = 43.1 bits (100), Expect = 9e-04 Identities = 50/218 (22%), Positives = 82/218 (37%), Gaps = 11/218 (5%) Query: 286 GVEEAKQELQEVVEFLKNPQKFTILGGKLPKG---ILLVGPPGTGKTLLARAVAGEADVP 342 G+E EL V++ P GG L G +LL GPPG GKT + A + Sbjct: 437 GLEALVSELCAVLKPRLQP------GGALLTGTSSVLLRGPPGCGKTTVVAAACSHLGLH 490 Query: 343 FYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHPYSRQT 402 S G ++++ +F A+ P V+ + +D +G R Sbjct: 491 LLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAVLLLTAVDLLGRDRDGLGEDARVMAV 550 Query: 403 INQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGRTEILKWY 462 + LL D ++++ T+ A D F ++ VP R IL+ Sbjct: 551 LRHLLLNEDPLNSCPPLMVVATTS--RAQDLPADVQTAFPHELEVPALSEGQRLSILRAL 608 Query: 463 LNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 + Q V+ +AR GF +L L+ ++ A Sbjct: 609 TAHLPLGQEVNLAQLARRCAGFVVGDLYALLTHSSRAA 646 >gi|5901990 katanin p60 subunit A 1 [Homo sapiens] Length = 491 Score = 145 bits (367), Expect = 1e-34 Identities = 100/278 (35%), Positives = 154/278 (55%), Gaps = 16/278 (5%) Query: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLA 332 Q NV ++ + + EAK+ L+E V + P+ F G + P KG+L+VGPPGTGKTLLA Sbjct: 202 QNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLA 259 Query: 333 RAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIE 392 +AVA E F+ S S + G +R LF A+ +P IFIDE+DS+ +R Sbjct: 260 KAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGT 319 Query: 393 SPMHPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQV 445 S H SR+ +LL +MDG P++ V+++ ATNFP +D AL R R + ++ Sbjct: 320 SEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRI 377 Query: 446 TVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGK 505 +P P KGR E+L+ L +++ VD IA G+SGA++ N+ A+L A Sbjct: 378 YIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRI 437 Query: 506 EMVTMKEL-EFSKDKILMGPERRSVEIDNK--NKTITA 540 E +T +E+ SK+++ M E+ K +K+++A Sbjct: 438 EGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKSVSA 475 >gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] Length = 490 Score = 145 bits (365), Expect = 2e-34 Identities = 97/275 (35%), Positives = 154/275 (56%), Gaps = 16/275 (5%) Query: 278 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLARAV 335 ++ ++ + +EEAK+ L+E V + P F G + P KG+L+VGPPGTGKT+LA+AV Sbjct: 204 SIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTMLAKAV 261 Query: 336 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 395 A E F+ S S + G +R LF A+ AP IFIDE+DS+ +R S Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDE 321 Query: 396 HPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVP 448 H SR+ ++LL +MDG P++ V+++ ATNFP +D AL R R + ++ +P Sbjct: 322 HEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIP 379 Query: 449 RPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMV 508 P KGR E+LK L +++ D + E IA G+SGA++ N+ A+L A + Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439 Query: 509 TMKELE-FSKDKILMGPERRSVEIDNKN--KTITA 540 + +E+ SK+++ M + E+ K K+++A Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSA 474 >gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] Length = 490 Score = 145 bits (365), Expect = 2e-34 Identities = 97/275 (35%), Positives = 154/275 (56%), Gaps = 16/275 (5%) Query: 278 NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLLARAV 335 ++ ++ + +EEAK+ L+E V + P F G + P KG+L+VGPPGTGKT+LA+AV Sbjct: 204 SIHWDDIADLEEAKKLLREAVVLPMWMPDFFK--GIRRPWKGVLMVGPPGTGKTMLAKAV 261 Query: 336 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 395 A E F+ S S + G +R LF A+ AP IFIDE+DS+ +R S Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSDE 321 Query: 396 HPYSRQTINQLLAEMDGF-------KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVP 448 H SR+ ++LL +MDG P++ V+++ ATNFP +D AL R R + ++ +P Sbjct: 322 HEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIP 379 Query: 449 RPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMV 508 P KGR E+LK L +++ D + E IA G+SGA++ N+ A+L A + Sbjct: 380 LPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMRRRINGL 439 Query: 509 TMKELE-FSKDKILMGPERRSVEIDNKN--KTITA 540 + +E+ SK+++ M + E+ K K+++A Sbjct: 440 SPEEIRALSKEELQMPVTKGDFELALKKIAKSVSA 474 >gi|4505725 peroxin1 [Homo sapiens] Length = 1283 Score = 142 bits (358), Expect = 1e-33 Identities = 80/225 (35%), Positives = 127/225 (56%), Gaps = 2/225 (0%) Query: 277 KNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAV 335 +++ ++ + G+ E +Q L + ++ K P+ F L + GILL GPPGTGKTLLA + Sbjct: 835 RDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVI 894 Query: 336 AGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM 395 A E+ + F G E ++G +R++F A+A PC++F DE +S+ +R Sbjct: 895 ARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNT 954 Query: 396 HPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 455 R +NQLL ++DG + +GV ++ AT+ P+ +D AL+RPGR D V P PD R Sbjct: 955 GVTDR-VVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSR 1013 Query: 456 TEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 EIL + + VD + +A T F+GA+L+ L+ A L+A Sbjct: 1014 LEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEA 1058 >gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] Length = 444 Score = 132 bits (333), Expect = 9e-31 Identities = 85/231 (36%), Positives = 135/231 (58%), Gaps = 10/231 (4%) Query: 274 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLL 331 ++ NV + V G+E AK+ L+E V +K P FT G + P +GILL GPPGTGK+ L Sbjct: 126 IERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYL 183 Query: 332 ARAVAGEAD-VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 390 A+AVA EA+ F+ S S+ ++G ++NLF+ A+ N P +IFIDE+DS+ G R Sbjct: 184 AKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSR 243 Query: 391 IESPMHPYSRQTINQLLAEMDGF-KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 449 E+ +R+ + L +M G N+G++++GATN P LD+A+ R RF+ ++ +P Sbjct: 244 SENESEA-ARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR--RFEKRIYIPL 300 Query: 450 PDVKGRTEILKWYLNKIKFD-QSVDPEIIARGTVGFSGAELENLVNQAALK 499 P+ R + K +L + D + R T G+SGA++ +V A ++ Sbjct: 301 PEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQ 351 >gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens] Length = 437 Score = 128 bits (322), Expect = 2e-29 Identities = 83/232 (35%), Positives = 137/232 (59%), Gaps = 12/232 (5%) Query: 274 VQMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLP-KGILLVGPPGTGKTLL 331 ++ N+ + V G+E AK+ L+E V +K P FT G + P +GILL GPPGTGK+ L Sbjct: 119 MEKPNIRWNDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYL 176 Query: 332 ARAVAGEAD-VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 390 A+AVA EA+ F+ S S+ ++G ++NLF A+ + P +IFIDE+DS+ G R Sbjct: 177 AKAVATEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSR 236 Query: 391 IESPMHPYSRQTINQLLAEMDGF-KPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPR 449 E+ +R+ + L +M G N+G +++GATN P LD+A+ R RF+ ++ +P Sbjct: 237 NENESEA-ARRIKTEFLVQMQGVGNNNDGTLVLGATNIPWVLDSAIRR--RFEKRIYIPL 293 Query: 450 PDVKGRTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALK 499 P+ R ++ + +L + + D I +AR T G+SGA++ +V + ++ Sbjct: 294 PEEAARAQMFRLHLGSTPHNLT-DANIHELARKTEGYSGADISIIVRDSLMQ 344 >gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] Length = 1390 Score = 127 bits (320), Expect = 3e-29 Identities = 88/240 (36%), Positives = 130/240 (54%), Gaps = 13/240 (5%) Query: 271 VDPVQM-KNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGK 328 VDP+Q+ +V F+ V G+ L+E+V F L P+ F + P+G L GPPGTGK Sbjct: 414 VDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGK 473 Query: 329 TLLARAVAGEAD-----VPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDEL 383 TL+ARA+A E V F+ G++ +VG ++R LF +A P +IF DE+ Sbjct: 474 TLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPSIIFFDEI 533 Query: 384 DSVGGKRIESPMHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDM 443 D + R S ++ LLA MDG +++IGATN +++D AL RPGRFD Sbjct: 534 DGLAPVR-SSRQDQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDR 592 Query: 444 QVTVPRPDVKGRTEILKWYL---NKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500 + PD + R EILK + N D + E +A VG+ GA+++++ +AAL A Sbjct: 593 EFLFSLPDKEARKEILKIHTRDWNPKPLDTFL--EELAENCVGYCGADIKSICAEAALCA 650 >gi|40806170 spastin isoform 2 [Homo sapiens] Length = 584 Score = 126 bits (316), Expect = 8e-29 Identities = 94/266 (35%), Positives = 148/266 (55%), Gaps = 21/266 (7%) Query: 279 VTFEHVKGVEEAKQELQEVVEFLK-NPQKFTILGGKLP-KGILLVGPPGTGKTLLARAVA 336 V F+ + G + AKQ LQE+V P+ FT G + P +G+LL GPPG GKT+LA+AVA Sbjct: 307 VKFDDIAGQDLAKQALQEIVILPSLRPELFT--GLRAPARGLLLFGPPGNGKTMLAKAVA 364 Query: 337 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMH 396 E++ F+ S + +VG G +R LF A+ P +IFIDE+DS+ +R E H Sbjct: 365 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGE-H 423 Query: 397 PYSRQTINQLLAEMDGFKP--NEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454 SR+ + L E DG + ++ V+++GATN P+ LD A++R RF +V V P+ + Sbjct: 424 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEET 481 Query: 455 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 512 R +LK L K + E+ +AR T G+SG++L L AAL ++E Sbjct: 482 RLLLLKNLLCK-QGSPLTQKELAQLARMTDGYSGSDLTALAKDAALG---------PIRE 531 Query: 513 LEFSKDKILMGPERRSVEIDNKNKTI 538 L+ + K + E R++ + + +++ Sbjct: 532 LKPEQVKNMSASEMRNIRLSDFTESL 557 >gi|11875211 spastin isoform 1 [Homo sapiens] Length = 616 Score = 126 bits (316), Expect = 8e-29 Identities = 94/266 (35%), Positives = 148/266 (55%), Gaps = 21/266 (7%) Query: 279 VTFEHVKGVEEAKQELQEVVEFLK-NPQKFTILGGKLP-KGILLVGPPGTGKTLLARAVA 336 V F+ + G + AKQ LQE+V P+ FT G + P +G+LL GPPG GKT+LA+AVA Sbjct: 339 VKFDDIAGQDLAKQALQEIVILPSLRPELFT--GLRAPARGLLLFGPPGNGKTMLAKAVA 396 Query: 337 GEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMH 396 E++ F+ S + +VG G +R LF A+ P +IFIDE+DS+ +R E H Sbjct: 397 AESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLCERREGE-H 455 Query: 397 PYSRQTINQLLAEMDGFKP--NEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454 SR+ + L E DG + ++ V+++GATN P+ LD A++R RF +V V P+ + Sbjct: 456 DASRRLKTEFLIEFDGVQSAGDDRVLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEET 513 Query: 455 RTEILKWYLNKIKFDQSVDPEI--IARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKE 512 R +LK L K + E+ +AR T G+SG++L L AAL ++E Sbjct: 514 RLLLLKNLLCK-QGSPLTQKELAQLARMTDGYSGSDLTALAKDAALG---------PIRE 563 Query: 513 LEFSKDKILMGPERRSVEIDNKNKTI 538 L+ + K + E R++ + + +++ Sbjct: 564 LKPEQVKNMSASEMRNIRLSDFTESL 589 >gi|31742536 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 125 bits (314), Expect = 1e-28 Identities = 80/224 (35%), Positives = 127/224 (56%), Gaps = 8/224 (3%) Query: 279 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 337 V +E + GVE AK ++E+V + + P FT L G PKGILL GPPGTGKTL+ + +A Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKCIAS 456 Query: 338 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 397 ++ F+ S S +VG G +R LF A+ P VIFIDE+DS+ +R + H Sbjct: 457 QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGE-HE 515 Query: 398 YSRQTINQLLAEMDG--FKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 455 SR+ + L ++DG + ++++GATN P+ +D A R R ++ +P P+ R Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASAR 573 Query: 456 TEILKWYLNKIKFDQSVDP-EIIARGTVGFSGAELENLVNQAAL 498 +I+ ++K + S + E I + + FSGA++ L +A+L Sbjct: 574 KQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617 >gi|112789543 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 125 bits (314), Expect = 1e-28 Identities = 80/224 (35%), Positives = 127/224 (56%), Gaps = 8/224 (3%) Query: 279 VTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 337 V +E + GVE AK ++E+V + + P FT L G PKGILL GPPGTGKTL+ + +A Sbjct: 398 VNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKCIAS 456 Query: 338 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 397 ++ F+ S S +VG G +R LF A+ P VIFIDE+DS+ +R + H Sbjct: 457 QSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDGE-HE 515 Query: 398 YSRQTINQLLAEMDG--FKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 455 SR+ + L ++DG + ++++GATN P+ +D A R R ++ +P P+ R Sbjct: 516 SSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEAARR--RLVKRLYIPLPEASAR 573 Query: 456 TEILKWYLNKIKFDQSVDP-EIIARGTVGFSGAELENLVNQAAL 498 +I+ ++K + S + E I + + FSGA++ L +A+L Sbjct: 574 KQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLCREASL 617 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.134 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,792,980 Number of Sequences: 37866 Number of extensions: 1070738 Number of successful extensions: 3352 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 52 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 3191 Number of HSP's gapped (non-prelim): 104 length of query: 716 length of database: 18,247,518 effective HSP length: 109 effective length of query: 607 effective length of database: 14,120,124 effective search space: 8570915268 effective search space used: 8570915268 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.