Guide to the Human Genome
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Search of human proteins with 73486666

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
sapiens]
         (921 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...  1971   0.0  
gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...  1427   0.0  
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   771   0.0  
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  665   0.0  
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               617   e-176
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   561   e-159
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   560   e-159
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   558   e-159
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     553   e-157
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     548   e-156
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   548   e-156
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]        548   e-156
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     541   e-153
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   541   e-153
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      537   e-152
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   536   e-152
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   536   e-152
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      532   e-151
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              530   e-150
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    523   e-148
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   523   e-148
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         518   e-147
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   518   e-146
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   518   e-146
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   518   e-146
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       517   e-146
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   517   e-146
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   513   e-145
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   513   e-145
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   513   e-145

>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 1971 bits (5106), Expect = 0.0
 Identities = 921/921 (100%), Positives = 921/921 (100%)

Query: 1   MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI 60
           MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI
Sbjct: 1   MKTCWKIPVFFFVCSFLEPWASAAVKRRPRFPVNSNSNGGNELCPKIRIGQDDLPGFDLI 60

Query: 61  SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT 120
           SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT
Sbjct: 61  SQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMT 120

Query: 121 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW 180
           GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW
Sbjct: 121 GSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQW 180

Query: 181 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI 240
           HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI
Sbjct: 181 HKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLI 240

Query: 241 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP 300
           HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP
Sbjct: 241 HCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP 300

Query: 301 PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP 360
           PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP
Sbjct: 301 PGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP 360

Query: 361 GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 420
           GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS
Sbjct: 361 GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 420

Query: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 480
           GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK
Sbjct: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK 480

Query: 481 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 540
           GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP
Sbjct: 481 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 540

Query: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 600
           GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM
Sbjct: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 600

Query: 601 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 660
           GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP
Sbjct: 601 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 660

Query: 661 GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 720
           GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR
Sbjct: 661 GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 720

Query: 721 GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 780
           GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS
Sbjct: 721 GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 780

Query: 781 LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 840
           LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK
Sbjct: 781 LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 840

Query: 841 GERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900
           GERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF
Sbjct: 841 GERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900

Query: 901 CEPASCTMQAGQRAFNKGPDP 921
           CEPASCTMQAGQRAFNKGPDP
Sbjct: 901 CEPASCTMQAGQRAFNKGPDP 921


>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score = 1427 bits (3695), Expect = 0.0
 Identities = 654/655 (99%), Positives = 655/655 (100%)

Query: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
           +RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG
Sbjct: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83

Query: 327 LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 386
           LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR
Sbjct: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 143

Query: 387 RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 446
           RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH
Sbjct: 144 RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 203

Query: 447 KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 506
           KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ
Sbjct: 204 KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 263

Query: 507 RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 566
           RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD
Sbjct: 264 RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323

Query: 567 AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS 626
           AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS
Sbjct: 324 AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS 383

Query: 627 RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE 686
           RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE
Sbjct: 384 RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE 443

Query: 687 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL 746
           AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL
Sbjct: 444 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL 503

Query: 747 PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 806
           PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE
Sbjct: 504 PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 563

Query: 807 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA 866
           NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA
Sbjct: 564 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA 623

Query: 867 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP
Sbjct: 624 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678



 Score =  431 bits (1109), Expect = e-120
 Identities = 267/651 (41%), Positives = 317/651 (48%), Gaps = 108/651 (16%)

Query: 261 PSQTTDERGPPGEQGPPGPPGPPGVPGIDGID---GDRGPKGPPGPPGPAGEPGK--PGA 315
           P     E G PG  G PG PG  G+ G DG     G +G KG PG PG  G PG+  PG 
Sbjct: 60  PPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGP 119

Query: 316 PGKPGT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGF-------PGRGIPGPPGP 365
           PG PGT   PG  G  GP G PG  G  G  G PG  G+ GF       P    PG  G 
Sbjct: 120 PGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 179

Query: 366 PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
           PG  G+ G  G  G +G+PGR+G  G  G  G  G +G            PPG  G  G+
Sbjct: 180 PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG---------PPGAQGLRGI 230

Query: 426 PGM---RGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 482
            G+   +G KGA+G  GEPG QG  G  GDQG+ G  G  GP G +G  G  GI G  G 
Sbjct: 231 TGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP 290

Query: 483 KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV 542
           KG  GL G  G  G+PG PG +G+   PG+ GP GD G +G  G+PG+PG KG  G  G 
Sbjct: 291 KGDTGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 347

Query: 543 DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
            G  G PG  G  G+PG+ GPPG+ G +   G  G+PG++G  G  GS G PGK G +G+
Sbjct: 348 TGAPGKPGQMGNSGKPGQQGPPGEVGPR---GPQGLPGSRGELGPVGSPGLPGKLGSLGS 404

Query: 603 SGKPGQQGPP------------GEVGPRGPQGLPGSRGEL---GPVGSPGLPGKLGSLGS 647
            G PG  GPP            GE GP+G QG  G  GE    G +G  GLPG  GS G+
Sbjct: 405 PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGN 464

Query: 648 PGLPGLPGPP---GLPGMKGDRGVVGEPGPKGEQGASGEEGEAG---------------- 688
           PG PGL GP    GLPG++G RG  G  G +GEQGA+G  G  G                
Sbjct: 465 PGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 524

Query: 689 --------------ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
                         +R + G  GLPG  G  G PG PG  G  G  G+ G+ G +GPPG 
Sbjct: 525 RVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGA 584

Query: 735 RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794
            G++G +G  G  G +GPPGR P                             GA GLPG 
Sbjct: 585 LGLRGPKGDLGEKGERGPPGRGPNGL-------------------------PGAIGLPGD 619

Query: 795 PGPP--GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 843
           PGP   G  G  GE G PG  GI G+PG  GPPG  G   P     + G+R
Sbjct: 620 PGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670



 Score =  368 bits (944), Expect = e-101
 Identities = 231/548 (42%), Positives = 267/548 (48%), Gaps = 94/548 (17%)

Query: 258 RITPSQTTDERGPPGEQGPPG------------------PPGPPGVPGIDGIDGDRGPKG 299
           R+ P      RGPPG  GPPG                  PPG  G PG+ G+ G +G KG
Sbjct: 134 RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193

Query: 300 PPGPP---------GPAGEPGKPGAPGKPGTPGADGLT------------------GPDG 332
             G P         G  GE G+ GA G PG  G  G+T                  GP G
Sbjct: 194 EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 253

Query: 333 SPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 388
            PG+ G +GQ+G PG  G +G  G    RGIPG PGP G  GLPG  GR G  G PG +G
Sbjct: 254 LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKG 313

Query: 389 PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 448
            PG PGPPG  G  G             PG  G PG  G+ G KG+ G  G+PG+ G+ G
Sbjct: 314 EPGKPGPPGDAGLQGL------------PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361

Query: 449 EEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGL---PGAPGDQG 505
           + G QG  GEVG +GP G  G RG  G VG  G  G  G  G PG  GL   PG PG +G
Sbjct: 362 KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 421

Query: 506 QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 565
            RG  GE GPKG++GA G  G  G  G  GD GLPG  G  G P      GEPG  GP G
Sbjct: 422 DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP------GEPGLRGPEG 475

Query: 566 DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP---------------GQQG 610
             GL G+ G  G PG +GV GE+G+TG PG  G  G +                   +  
Sbjct: 476 SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535

Query: 611 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG 670
              +    G  GLPG  G  GP G PG  G  G +G  GLPG+ GPPG  G++G +G +G
Sbjct: 536 ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 595

Query: 671 EPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA--GNPGEPGLRGPEGSRGLPGVEGP 728
           E   KGE+G  G     G  G  G IGLPG  G A  G  G  G RGP G  G+PGV GP
Sbjct: 596 E---KGERGPPGR----GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP 648

Query: 729 RGPPGPRG 736
            GPPG  G
Sbjct: 649 PGPPGLPG 656



 Score =  364 bits (934), Expect = e-100
 Identities = 222/501 (44%), Positives = 256/501 (51%), Gaps = 49/501 (9%)

Query: 424 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 483
           GL      +G  GE G PG  G  G  G  G  G+ G +GPPG  G  G  G  G  G+ 
Sbjct: 17  GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76

Query: 484 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 543
           G  G DG  GP G PG+ G +GQ+G PG  G +G  G    RGIPG PGP G  GLPG  
Sbjct: 77  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGEL 132

Query: 544 GRDGIPGMPGTKGEPGKPGPPGDAGLQGL------------PGVPGIPGAKGVAGEKGST 591
           GR G  G PG +G PG PGPPG  G  G             PG  G PG  G+ G KG+ 
Sbjct: 133 GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 192

Query: 592 GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 651
           G  G+PG+ G+ G+ G QG  GEVG +GP G  G RG  G VG  G  G  G  G PG  
Sbjct: 193 GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 252

Query: 652 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP--- 708
           GL   PG PG +G RG  GE GPKG++GA G  G  G  G  GD GLPG  G  G P   
Sbjct: 253 GL---PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309

Query: 709 ---GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 765
              GEPG  GP G  GL G+ G  G PG +GV GE+G+TG PG  G  G +         
Sbjct: 310 GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP------ 363

Query: 766 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP 825
                     +     +    G  GLPG  G  GP G PG  G  G +G  GLPG+ GPP
Sbjct: 364 ---------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 414

Query: 826 GALGLRGPKGDLGE---KGERGPPGR----GPNGLPGAIGLPGDPGPASYGRNGRDGERG 878
           G  G++G +G +GE   KGE+G  G     G  G  G IGLPG  G A  G  G  G RG
Sbjct: 415 GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA--GNPGEPGLRG 472

Query: 879 PPGVAGIPGVPGPPGPPGLPG 899
           P G  G+PGV GP GPPG  G
Sbjct: 473 PEGSRGLPGVEGPRGPPGPRG 493



 Score =  206 bits (525), Expect = 6e-53
 Identities = 130/316 (41%), Positives = 152/316 (48%), Gaps = 43/316 (13%)

Query: 256 PARITPSQTTDERGPPGEQGPPGPPG---------PPGVPGIDGIDGDRGPKGPPGPPGP 306
           P ++  S    ++GPPGE GP GP G         P G PG+ G  G  G  G PG PGP
Sbjct: 354 PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 413

Query: 307 AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGP 365
            G PG  G  G  G PG  G  G  G  G  G +G+ G+ G+PG +G  G  G PG  GP
Sbjct: 414 PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473

Query: 366 PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC---------- 415
            G+ GLPG  G  GP G  G +G  G  G PG +G  G    D      C          
Sbjct: 474 EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533

Query: 416 --------PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA 467
                     G +G PG PG  G  G  GE G PG+ G +G           G +GPPGA
Sbjct: 534 MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP---------GIKGPPGA 584

Query: 468 QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPP--GEAGPKGDRGAEGAR 525
            GLRG  G +G+KGE+G  G     GP GLPGA G  G  GP   G  G  G+RG  G  
Sbjct: 585 LGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVA 640

Query: 526 GIPGLPGPKGDTGLPG 541
           GIPG+PGP G  GLPG
Sbjct: 641 GIPGVPGPPGPPGLPG 656


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  771 bits (1992), Expect = 0.0
 Identities = 368/644 (57%), Positives = 422/644 (65%), Gaps = 5/644 (0%)

Query: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
           RGPPGE+GPPGPPGPPGVPG DGIDGD GP G  GPPGP GEPGK G  G  G PG DGL
Sbjct: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85

Query: 328 TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 387
           TG  G PG +G  G KG+PG+PG  G PG G  GPPGPPG  GLPGE+G  GP GDPG  
Sbjct: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD 145

Query: 388 GPPGPPGPPGPRGTIGFHDG-----DPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPG 442
           GP GPPGPPG  G  G   G     D LCP  CPPG  G PGL G++GH G +G +G+PG
Sbjct: 146 GPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG 205

Query: 443 RQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 502
            QG  G +GD G  GE G  GPPG QG+RG  G+ G KGE G  G  G  G  G  G PG
Sbjct: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPG 265

Query: 503 DQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPG 562
           ++G RGPPG AG KGD G+ G RG  G+ GPKG TG PG++G+DG PG PG KG  G+ G
Sbjct: 266 EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325

Query: 563 PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG 622
            PG  G QGL GVPG PG KG  G++G  G  G PG  G  GK G+ GP GE+GP+G  G
Sbjct: 326 QPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385

Query: 623 LPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASG 682
             G +GE GPVG PG  G+ G  G  G PG+PGP GLPG+KGD+G  G+ GP+G+ G  G
Sbjct: 386 QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG 445

Query: 683 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG 742
             G  GE+GE G+ G PGPKG  G  GEPG  GP G  G PGV+G  GPPGPRG+ G +G
Sbjct: 446 VAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRG 505

Query: 743 ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802
             G PG QG  GR  TDQHI  V ++++QE  AE+A S KR   GA G+ G PGPPGPPG
Sbjct: 506 VPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPG 565

Query: 803 PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGD 862
            PG+ G  G  G RG+PGI G  G +G  GPKG  GEKG+ G  GRG  G+PG  G+PG 
Sbjct: 566 YPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGL 625

Query: 863 PGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
           PG      NG+DG+RG PG  G  G PG PGP GLPGFCEPA+C
Sbjct: 626 PGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAAC 669



 Score =  438 bits (1127), Expect = e-122
 Identities = 266/643 (41%), Positives = 321/643 (49%), Gaps = 100/643 (15%)

Query: 265 TDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 324
           T  +G PG  G PG  G PG+PG  G+ G  G  GPPGPPGP G PG+ G  G  G PG 
Sbjct: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGP-GFAGPPGPPGPVGLPGEIGIRGPKGDPGP 144

Query: 325 DGLTGPDGSPGSIGSKGQKGEPGVPGSRGF--PGRGIPGPPGPPGTAGLPGELGRVGPVG 382
           DG +GP G PG  G  G     G+ GS  F  P    PG  GPPG  G+ G  G+ G +G
Sbjct: 145 DGPSGPPGPPGKPGRPGT--IQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILG 202

Query: 383 DPGRRGPPGP------------PGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRG 430
           DPG +G PGP            PGPPGP+G  G+            PG +G  G  G  G
Sbjct: 203 DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGY------------PGMAGPKGETGPHG 250

Query: 431 HKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 490
           +KG  G IG  G  G +G  G  G  GE G +G PG +G +GITG  G  G  G  G DG
Sbjct: 251 YKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDG 310

Query: 491 EPGPQGL---------PGAPGDQGQRGPPGEAGPK---GDRGAEGARGIPGLPGPKGDTG 538
            PG  G+         PG+PG QG  G PG+ G K   GD+G  G +G+PG  GP G  G
Sbjct: 311 TPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEG 370

Query: 539 LPGVDGRDGIPGMPGTKGEP------GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTG 592
            PG  G  G  G+ G KG+       G+PGP G  G +G  G PGIPG +G+ G KG  G
Sbjct: 371 EPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKG 430

Query: 593 APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 652
           +PGK G  G  G PG  G PGE G +G  G PG +G+ G  G PG PG  G  G+PG+ G
Sbjct: 431 SPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQG 490

Query: 653 LPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE------RGELGDIGLPGPKGSAG 706
            PGPPG  G+ G+RGV G+PG +G +G    +    +      + +L ++ +   + + G
Sbjct: 491 YPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALG 550

Query: 707 NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 766
             G  G  GP G  G PG +GP G PGPRGV G  GA G  G  GP G            
Sbjct: 551 AVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKG------------ 598

Query: 767 MRVIQEHFAEMAASLKRPDSGATGLPGR--PGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824
                          KR + G  G  GR  PG PGPPG PG  G PGQ  I G  G +G 
Sbjct: 599 ---------------KRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQ-AINGKDGDRGS 642

Query: 825 PGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 867
           PGA             GE G P     GLPG +GLPG   PA+
Sbjct: 643 PGA------------PGEAGRP-----GLPGPVGLPGFCEPAA 668



 Score =  400 bits (1027), Expect = e-111
 Identities = 248/624 (39%), Positives = 292/624 (46%), Gaps = 99/624 (15%)

Query: 352 RGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLC 411
           RG PG    GPPGPPG  G+PG  G  G  G PG+ GPPGP G PG  G           
Sbjct: 26  RGPPGER--GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAG----------- 72

Query: 412 PNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE--VGAQGPPGAQG 469
               P G  G PG+ G+ G KG  G +G PG +G  G  G  G  G    G  GPPG  G
Sbjct: 73  ----PDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVG 128

Query: 470 LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD-----------------QGQRGPPGE 512
           L G  GI G KG+ G  G  G PGP G PG PG                   G +GPPG 
Sbjct: 129 LPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGL 188

Query: 513 AGPKGDRGAEGARGIPG---LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL 569
            G KG  G  G  G PG    PGPKGD G  G  G  G PG  G +G PG  GP G+ G 
Sbjct: 189 QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGP 248

Query: 570 QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629
            G  G+ G  GA G  GE+G  G PG+ G+ G+ G PG +GP G  GP+G  G PG  G+
Sbjct: 249 HGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK 308

Query: 630 LGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPKGEQGASG---E 683
            G  G+PG+ G  G  G PG PG   L G PG PG KG  G  GEPGP+G  G SG   +
Sbjct: 309 DGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGK 368

Query: 684 EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGA 743
           EGE G RGE+G  G+ G KG  G  G  G  GP+G +G  G +GP G PGP+G+ G +G 
Sbjct: 369 EGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD 428

Query: 744 TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP 803
            G PG  GP G+                    +   +    + G  G  G PGP G  G 
Sbjct: 429 KGSPGKTGPRGKV------------------GDPGVAGLPGEKGEKGESGEPGPKGQQGV 470

Query: 804 PGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGEKGERGPPGRGPNGLP------ 854
            GE G+PG  G  G PG++G   PPG  GL G +G  G+ G +G  GR            
Sbjct: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVAL 530

Query: 855 -------------------GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895
                              GA+G+ G PGP         G  G PG  G  G PGP G P
Sbjct: 531 KMLQEQLAEVAVSAKREALGAVGMMGPPGPP--------GPPGYPGKQGPHGHPGPRGVP 582

Query: 896 GLPGFCEPASCTMQAGQRAFNKGP 919
           G+ G       T   G+R     P
Sbjct: 583 GIVGAVGQIGNTGPKGKRGEKGDP 606



 Score =  326 bits (836), Expect = 5e-89
 Identities = 192/472 (40%), Positives = 229/472 (48%), Gaps = 30/472 (6%)

Query: 480 KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 539
           +G  G RG  G PGP G+PG+ G  G  GPPG+AGP G +G  G  G  G  G  G  GL
Sbjct: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85

Query: 540 PGVDGRDGIPGMPGTKGEPGKPGPPG-----DAGLQGLPGVPGIPGAKGVAGEKGSTGAP 594
            G  G  G  G+PG KG+PG PGPPG      AG  G PG  G+PG  G+ G KG  G  
Sbjct: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD 145

Query: 595 GKPGQMGNSGKPGQQG-----------------PPGEVGPRGPQGLPGSRGELGPVGSPG 637
           G  G  G  GKPG+ G                 PPG  GP G QG+ G  G+ G +G PG
Sbjct: 146 GPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG 205

Query: 638 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
             GK G  G  G  G  G PG PG +G RG  G  GPKGE G  G +G  G  G  G  G
Sbjct: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPG 265

Query: 698 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 757
             GP+G  G  GE G  G  G RG  G+ GP+G  GP G+ G+ G  G PG++G  G+A 
Sbjct: 266 EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325

Query: 758 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                    +  +            + + G  GLPG  GPPG  G PG  G  G  GI G
Sbjct: 326 QPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385

Query: 818 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY-------G 869
             G +G  G +G  GP+G  G KGE+GPPG  GP GLPG  G  G PG           G
Sbjct: 386 QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG 445

Query: 870 RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
             G  GE+G  G +G PG  G  G  G PG+  P+      G + +   P P
Sbjct: 446 VAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGP 497



 Score =  245 bits (626), Expect = 1e-64
 Identities = 158/378 (41%), Positives = 188/378 (49%), Gaps = 49/378 (12%)

Query: 264 TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
           T   +G  G+ G PG PG  G+ G+ G  G +G  G  G PGP G PG  G PGK G PG
Sbjct: 314 TPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373

Query: 324 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLP------GELG 376
             G  GP G  G  G +G++G  G PG +G  G +G  GPPG PG  GLP      G  G
Sbjct: 374 PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433

Query: 377 RVGP---VGD------PGRRGPPGPPGPPGPRGTIGFHDGDPLCP----NACPPGRSGYP 423
           + GP   VGD      PG +G  G  G PGP+G  G   G+P  P    +A  PG  GYP
Sbjct: 434 KTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVR-GEPGYPGPSGDAGAPGVQGYP 492

Query: 424 GLPGMRGHKGAKGEIGEPGRQGHKGEEGD------------QGELGEVGAQGPP---GAQ 468
           G PG RG  G +G  G+PGRQG +G +              Q +L EV         GA 
Sbjct: 493 GPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV 552

Query: 469 GLRGITGIVGDKGEKGARGLDGEPGPQGLP---GAPGDQGQRGPPGEAGPKGDRGAEGAR 525
           G+ G  G  G  G  G +G  G PGP+G+P   GA G  G  GP G+ G KGD G  G R
Sbjct: 553 GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG-R 611

Query: 526 GIPGLPGPKGDTGLPG-----VDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG 580
           G PG+PGP G  GLPG     ++G+DG  G PG  GE G+PG PG  GL G        G
Sbjct: 612 GHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671

Query: 581 AKGVAG----EKGSTGAP 594
           A   A     E GS   P
Sbjct: 672 ASAYASARLTEPGSIKGP 689



 Score =  202 bits (514), Expect = 1e-51
 Identities = 131/297 (44%), Positives = 145/297 (48%), Gaps = 26/297 (8%)

Query: 259 ITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 318
           I P     ++G  GE+GP G PGP       G  G +G +GPPG PGP G PG  G  G 
Sbjct: 378 IGPQGIMGQKGDQGERGPVGQPGP------QGRQGPKGEQGPPGIPGPQGLPGVKGDKGS 431

Query: 319 PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGR 377
           PG  G  G  G  G  G  G KG+KGE G PG +G  G RG PG PGP G AG PG  G 
Sbjct: 432 PGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGY 491

Query: 378 VGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD-------------PLCPNACPPGRSGYPG 424
            GP G  G  G  G PG PG +G  G    D              L   A    R    G
Sbjct: 492 PGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREAL-G 550

Query: 425 LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 484
             GM G  G  G  G PG+QG  G  G +G  G VGA G  G  G +G  G  GD GE G
Sbjct: 551 AVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVG 610

Query: 485 ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG 541
            RG  G PGP G+PG PG  GQ    G+ G +G  GA G  G PGLPGP    GLPG
Sbjct: 611 -RGHPGMPGPPGIPGLPGRPGQ-AINGKDGDRGSPGAPGEAGRPGLPGP---VGLPG 662



 Score =  134 bits (337), Expect = 4e-31
 Identities = 86/233 (36%), Positives = 103/233 (44%), Gaps = 28/233 (12%)

Query: 255 LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314
           LP        + E GP G+QG  G PG PG  G  G  G +G  GPPGP G AG  G PG
Sbjct: 449 LPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPG 508

Query: 315 APGKPGTPGADGL------------------TGPDGSPGSIGSKGQKGEPGVPGSRGFPG 356
            PG+ G  G D                            ++G+ G  G PG PG  G+PG
Sbjct: 509 QPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPG 568

Query: 357 RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP 416
           +   GP G PG  G+PG +G VG +G+ G +G  G  G PG  G      G P  P   P
Sbjct: 569 K--QGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGR-----GHPGMPG--P 619

Query: 417 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 469
           PG  G PG PG +   G  G+ G PG  G  G  G  G +G  G   P    G
Sbjct: 620 PGIPGLPGRPG-QAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671



 Score =  102 bits (254), Expect = 2e-21
 Identities = 61/139 (43%), Positives = 66/139 (47%), Gaps = 16/139 (11%)

Query: 777 MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD 836
           +A +  R   G  G PG PGPPG PG  G +G  G  G  G PG KG PG  G  GP G 
Sbjct: 20  LALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGK 79

Query: 837 LGEKGERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--------- 886
            G  G  G  G  GP G+PG  G PG PGP      G  G  GPPG  G+P         
Sbjct: 80  PGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPK 139

Query: 887 ------GVPGPPGPPGLPG 899
                 G  GPPGPPG PG
Sbjct: 140 GDPGPDGPSGPPGPPGKPG 158



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 45/99 (45%), Positives = 52/99 (52%), Gaps = 11/99 (11%)

Query: 812 QMGIRGLPGIKGPPGALGLRGPKGDLGE------KGERGPPGR----GPNGLPGAIGLPG 861
           Q+ +  L  I+GPPG  G  GP G  G        G+ GPPG+    GP G PG  G  G
Sbjct: 16  QVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDG 75

Query: 862 DPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             G P   G  G  GE GP G+ G+ G PG PGPPGLPG
Sbjct: 76  PDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPG 114


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  665 bits (1717), Expect = 0.0
 Identities = 325/642 (50%), Positives = 405/642 (63%), Gaps = 10/642 (1%)

Query: 272 GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---PGTPGADGLT 328
           G  GPPGPPGPPG PG DGIDG+ GP G PGPPGP G PGKPG PG+   PG PG DGLT
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLT 88

Query: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD---PG 385
           G DG PG  G+ G++G  G PG  G  G+G+PGPPG  G +G PG +G  GP G    PG
Sbjct: 89  GRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPG 148

Query: 386 RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 445
             GPPGPPGPPG  G +     D  CP+ CPPG  G PG+PG +G  G KGE GE G+ G
Sbjct: 149 LPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDG 208

Query: 446 HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQG 505
            KG+ G  G  G  G+ G  G +GLRG+ G +G  G++G  G  G PG  G PG  GD+G
Sbjct: 209 EKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKAGDRG 268

Query: 506 QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 565
           +RGP G  GPKGD G  G +G PG+ GP G+ G+PG DG++G+PG+ G KGE G+ G PG
Sbjct: 269 ERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAGRNGAPG 328

Query: 566 DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG 625
           + G  GLPG+PG  G+KG  GE+G  G  G+ G  G  G PG  G PGE G  G +G  G
Sbjct: 329 EKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAG 388

Query: 626 SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEG 685
           + G  GP G+PG+ G  G  GS G PGLPGP GL G  GDRG  G  GPKG+QG +G +G
Sbjct: 389 ALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDG 448

Query: 686 EAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745
             G++GELG  GL GPKG +G+ GE G +G +G  G  GV+G  GPPGP G+QG  G  G
Sbjct: 449 LPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPG 508

Query: 746 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP-DSGATGLPGRPGPPGPPGPP 804
           + G  G PG+  ++Q I+++C  +I E  A++AA L++P   G+ G PG  GPPGPPGPP
Sbjct: 509 ITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPP 568

Query: 805 GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG 864
           G  G P   G RG PG +GP G LG  GP+G+ G++G++G  G G +G  G  G  G  G
Sbjct: 569 GSIGHP---GARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEGDQGPQGPQG 625

Query: 865 PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
                ++G+DG  G PG  G PG+PG  G  G PG C+ ++C
Sbjct: 626 VPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667



 Score =  414 bits (1065), Expect = e-115
 Identities = 265/629 (42%), Positives = 312/629 (49%), Gaps = 103/629 (16%)

Query: 268 RGPPGEQG---PPGPPG--------PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316
           +G PGE+G   PPGPPG        PPG  G+ G  G  G +GPPGP G  G PG PG P
Sbjct: 97  KGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPP 156

Query: 317 GKPGTPGA--DGLTG-------PDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPP 366
           G PG PG   +G T        P G PG  G  G KG  G  G +G  G+ G  G PGPP
Sbjct: 157 GPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPP 216

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426
           G AGLPG +G  GP    G RG PGP GPPG RG IGF  G P  P A  PG++G  G  
Sbjct: 217 GPAGLPGSVGLQGP---RGLRGLPGPLGPPGDRGPIGFR-GPPGIPGA--PGKAGDRGER 270

Query: 427 GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 486
           G  G +G KG++G PG +G  G  G  GE       G PG  G  G+ G+ G KGE G  
Sbjct: 271 GPEGFRGPKGDLGRPGPKGTPGVAGPSGE------PGMPGKDGQNGVPGLDGQKGEAGRN 324

Query: 487 GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
           G  GE GP GLPG PG  G +G  GE G  G+ G  G  G PG+P   GD G+PG  G  
Sbjct: 325 GAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVP---GDAGMPGERGEA 381

Query: 547 GIPGMPGTKGEPGKPGPPGDAGLQGL------PGVPGIPGAKGVAGEKGSTGAPGKPGQM 600
           G  G  G  G  G PG PG  G QG       PG+PG  G +G  G++G  GA G  G  
Sbjct: 382 GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQ 441

Query: 601 GNSGKPGQQGPPGEVGPR---GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 657
           G +G  G  G  GE+GP    GP+G  GSRGELGP G+    G  G+ G  G+PG PGP 
Sbjct: 442 GIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGT---QGPNGTSGVQGVPGPPGPL 498

Query: 658 GLPGMKGDRGVVGEPGPKGEQGASGEEGE--------------AGERGEL--GDIGLPGP 701
           GL G+ G  G+ G+PG  G++ +     E              A  R  L  G IG PGP
Sbjct: 499 GLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGP 558

Query: 702 KGSAGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQGEQGATGL--PGVQGPPGRA 756
            G  G PG PG  G  G+RG PG  GP    G PGPRG QG++G  G    G+ GP G  
Sbjct: 559 AGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGAGLDGPEG-- 616

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP-----GRPGPPGPPGPPGENGFPG 811
                                     +   G  G+P     G+ G PG PGPPG+ G PG
Sbjct: 617 -------------------------DQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPG 651

Query: 812 QMGIRGLPGIKGPPGALGLRGPKGDLGEK 840
            +G +G PGI       G     G +GEK
Sbjct: 652 AIGAQGTPGICDTSACQG--AVLGGVGEK 678



 Score =  395 bits (1014), Expect = e-109
 Identities = 255/626 (40%), Positives = 291/626 (46%), Gaps = 120/626 (19%)

Query: 358 GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP 417
           G+PGPPGPPG  G PG+ G  G  G PG  GPPGP G PG  G                P
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK---------------P 73

Query: 418 GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG--AQGLRGITG 475
           G +G PGLPG+ G  G         R G  G +G  GE G +G  GPPG   +GL G  G
Sbjct: 74  GEAGLPGLPGVDGLTG---------RDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124

Query: 476 IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAG--PKGDR----------GAEG 523
             G  G  G  GL G PGP GLPG PG  G  GPPG  G  P+G            G  G
Sbjct: 125 EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPG 184

Query: 524 ARGIPGLPGP---KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG 580
             G+PG  GP   KG+ G  G DG  G PG PG  G PG  G  G  GL+GLPG  G PG
Sbjct: 185 PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG 244

Query: 581 AKGVAGEKGSTGAPGKPGQMGNSGKPGQQG---PPGEVGPRGPQGLPGSRGELGPVGSPG 637
            +G  G +G  G PG PG+ G+ G+ G +G   P G++G  GP+G PG  G   P G PG
Sbjct: 245 DRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG---PSGEPG 301

Query: 638 LPGKLGSLGSPGLPGLPGPPG---LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 694
           +PGK G  G PGL G  G  G    PG KG  G+ G PG  G +G  GE G AGE GE G
Sbjct: 302 MPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAG 361

Query: 695 DIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG 754
             G PG  G AG PGE G  G  GS G  G +GP G PG RG QG++G+ G PG+ GP G
Sbjct: 362 PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421

Query: 755 RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMG 814
                                       R D G  G  G  GP G  G  G +G PG  G
Sbjct: 422 L---------------------------RGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKG 454

Query: 815 IRGLPGIKGPPGALGLRG---------PKGDLGEKGERGPPG----RGPNGLPGAIGLPG 861
             G  G+ GP G  G RG         P G  G +G  GPPG    +G  G+PG  G PG
Sbjct: 455 ELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514

Query: 862 DPG-----------------------------PASYGRNGRDGERGPPGVAGIPGVPGPP 892
            PG                             P + G  GR G  GPPG  G PG  G P
Sbjct: 515 VPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHP 574

Query: 893 GPPGLPGFCEPASCTMQAGQRAFNKG 918
           G  G PG+  P       G R  N+G
Sbjct: 575 GARGPPGYRGPTGELGDPGPRG-NQG 599



 Score =  386 bits (992), Expect = e-107
 Identities = 239/546 (43%), Positives = 271/546 (49%), Gaps = 83/546 (15%)

Query: 381 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
           VG PG  GPPGPPG PG  G  G   G P  P   PPG  G PG PG  G  G  G  G 
Sbjct: 28  VGLPGPPGPPGPPGKPGQDGIDG-EAGPPGLPG--PPGPKGAPGKPGKPGEAGLPGLPGV 84

Query: 441 PGRQGHKGEEGDQGELGEVGAQGPP-----GAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
            G  G  G  G +G  GE G+ GPP     G +GL G  G  G  G  G  GL G PGP 
Sbjct: 85  DGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPS 144

Query: 496 GLPGAPGDQGQRGPPGEAG--PKG----------DRGAEGARGIPGLPGP---KGDTGLP 540
           GLPG PG  G  GPPG  G  P+G            G  G  G+PG  GP   KG+ G  
Sbjct: 145 GLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGPTGYKGEQGEV 204

Query: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 600
           G DG  G PG PG  G PG  G  G  GL+GLPG  G PG +G  G +G  G PG PG+ 
Sbjct: 205 GKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPGKA 264

Query: 601 GNSGKPGQQ---GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 657
           G+ G+ G +   GP G++G  GP+G P   G  GP G PG+PGK G  G PGL G  G  
Sbjct: 265 GDRGERGPEGFRGPKGDLGRPGPKGTP---GVAGPSGEPGMPGKDGQNGVPGLDGQKGEA 321

Query: 658 ---GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR 714
              G PG KG  G+ G PG  G +G  GE G AGE GE G  G PG  G AG PGE G  
Sbjct: 322 GRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEA 381

Query: 715 GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHF 774
           G  GS G  G +GP G PG RG QG++G+ G PG+ GP                      
Sbjct: 382 GHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGP---------------------- 419

Query: 775 AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK 834
                       G  G  G  GP G  GP G+ G  G     GLPG KG  G  GL GPK
Sbjct: 420 -----------QGLRGDVGDRGPGGAAGPKGDQGIAGS---DGLPGDKGELGPSGLVGPK 465

Query: 835 GDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPG 893
           G+ G +GE GP G +GPNG  G  G+PG PGP               G+ G+PGVPG  G
Sbjct: 466 GESGSRGELGPKGTQGPNGTSGVQGVPGPPGPL--------------GLQGVPGVPGITG 511

Query: 894 PPGLPG 899
            PG+PG
Sbjct: 512 KPGVPG 517



 Score =  328 bits (842), Expect = 1e-89
 Identities = 204/490 (41%), Positives = 238/490 (48%), Gaps = 98/490 (20%)

Query: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGAPG 317
           E G  GE+G PGPPGP G+PG  G+ G RG +G PGP GP G+         PG PGAPG
Sbjct: 203 EVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGPPGIPGAPG 262

Query: 318 K---------------------PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG 356
           K                     PG  G  G+ GP G PG  G  GQ G PG+ G +G  G
Sbjct: 263 KAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGLDGQKGEAG 322

Query: 357 R-GIPGPPGPPGTAGLP---------GELGRVGPVGDPGRRGPPGPPGP---PGPRGTIG 403
           R G PG  GP G  GLP         GE GR G +G+ G  G PG PG    PG RG  G
Sbjct: 323 RNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAG 382

Query: 404 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG 463
            H G     +A   G  G PG PG+RG +G KG +G+PG  G +G  GD G+ G  GA G
Sbjct: 383 -HRG-----SAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAG 436

Query: 464 PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEG 523
           P G QG+ G  G+ GDKGE          GP GL G  G+ G RG  G  G +G  G  G
Sbjct: 437 PKGDQGIAGSDGLPGDKGEL---------GPSGLVGPKGESGSRGELGPKGTQGPNGTSG 487

Query: 524 ARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK---------------------------- 555
            +G+PG PGP G  G+PGV G  G PG+PG +                            
Sbjct: 488 VQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKP 547

Query: 556 ---GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 612
              G  G+PGP G  G  G PG  G PGA+G  G +G TG  G PG  GN G  G +G  
Sbjct: 548 LAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAA 607

Query: 613 GEVGPRGPQGLPGSRGELGPVGSPGLPG--KLGSLGSPGLPGLPGPPGLPGMKGDRGVVG 670
           G        GL G  G+ GP G  G+PG  K G  G+PG PG PG PGLPG  G +G  G
Sbjct: 608 G-------AGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPG 660

Query: 671 EPGPKGEQGA 680
                  QGA
Sbjct: 661 ICDTSACQGA 670



 Score =  322 bits (826), Expect = 8e-88
 Identities = 205/500 (41%), Positives = 242/500 (48%), Gaps = 55/500 (11%)

Query: 456 LGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP 515
           LGE+ A       GL G  G  G  G+ G  G+DGE GP GLPG PG +G  G PG+ G 
Sbjct: 16  LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75

Query: 516 KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV 575
            G  G  G  G+ G  GP G  G PG  G  G PG PG  G+ G PGPPG+AG+ G PG 
Sbjct: 76  AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGG 134

Query: 576 PGIPGAKGVAGEKGSTGAPGKPGQMGNSG---------------KPGQQGPPGEVGPRGP 620
            G+ G  G +G  G  G PG PG  G+ G                PG  GPPG  G +GP
Sbjct: 135 IGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGP 194

Query: 621 QGLPGSRGELG---------PVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD---RGV 668
            G  G +GE+G         P G  GLPG +G  G  GL GLPGP G PG +G    RG 
Sbjct: 195 TGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGP 254

Query: 669 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS---AGNPGEPGLRGPEGSRGLPGV 725
            G PG  G+ G  GE G  G RG  GD+G PGPKG+   AG  GEPG+ G +G  G+PG+
Sbjct: 255 PGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGL 314

Query: 726 EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
           +G +G  G  G  GE+G  GLPG+   PGRA +                 E     +  +
Sbjct: 315 DGQKGEAGRNGAPGEKGPNGLPGL---PGRAGSK---------------GEKGERGRAGE 356

Query: 786 SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGP 845
            G  G  G PG PG  G PGE G  G  G  G  G +GPPGA G+RG +G  G  G+ G 
Sbjct: 357 LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL 416

Query: 846 PGRGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901
           PG  P GL G +G  G  G A      G  G DG  G  G  G  G+ GP G  G  G  
Sbjct: 417 PG--PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGEL 474

Query: 902 EPASCTMQAGQRAFNKGPDP 921
            P       G       P P
Sbjct: 475 GPKGTQGPNGTSGVQGVPGP 494



 Score =  250 bits (639), Expect = 4e-66
 Identities = 167/442 (37%), Positives = 191/442 (43%), Gaps = 120/442 (27%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRG------------------PKGPPGPPGPAGEP 310
           GPPG++GP G  GPPG+PG  G  GDRG                  PKG PG  GP+GEP
Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300

Query: 311 GKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR------------- 357
           G PG  G+ G PG DG  G  G  G+ G KG  G PG+PG  G  G              
Sbjct: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360

Query: 358 GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD--GDPLCPN-- 413
           G  G PG PG AG+PGE G  G  G  G  GP GPPG PG RG  G     GDP  P   
Sbjct: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420

Query: 414 -----------ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ 462
                          G  G  G+ G  G  G KGE+G  G  G KGE G +GELG  G Q
Sbjct: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480

Query: 463 GP------------PGAQGLRGITGIVGDKGEKGARGLD--------------------- 489
           GP            PG  GL+G+ G+ G  G+ G  G +                     
Sbjct: 481 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540

Query: 490 -------------------GEPGPQGLPGAPGDQGQRGPPGEAGP------------KGD 518
                              G PGP G PG+ G  G RGPPG  GP            +GD
Sbjct: 541 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600

Query: 519 RGAEGARGIPGLPGPKGDTGLPGVDG-----RDGIPGMPGTKGEPGKPGPPGDAGLQGLP 573
           RG +GA G  GL GP+GD G  G  G     +DG  G PG  G PG PG PG  G QG P
Sbjct: 601 RGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTP 659

Query: 574 GVPGIPGAKGV----AGEKGST 591
           G+      +G      GEK  +
Sbjct: 660 GICDTSACQGAVLGGVGEKSGS 681



 Score =  218 bits (555), Expect = 2e-56
 Identities = 138/349 (39%), Positives = 160/349 (45%), Gaps = 61/349 (17%)

Query: 255 LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDR------------GPKGPPG 302
           LP R        ERG  GE G  GP G PGVPG  G+ G+R            GP+GPPG
Sbjct: 338 LPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPG 397

Query: 303 PPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------ 356
            PG  G  G+ G+ G PG PG  GL G  G  G  G+ G KG+ G+ GS G PG      
Sbjct: 398 APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELG 457

Query: 357 -RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC 415
             G+ GP G  G+ G  G  G  GP G  G +G PGPPGP G +G  G            
Sbjct: 458 PSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGV----------- 506

Query: 416 PPGRSGYPGLPGMRGHKG-------------------------AKGEIGEPGRQGHKGEE 450
            PG +G PG+PG    +                          A G IG PG  G  G  
Sbjct: 507 -PGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPP 565

Query: 451 GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPP 510
           G  G +G  GA+GPPG +G  G  G  G +G +G RG  G  G  GL G  GDQG +GP 
Sbjct: 566 GPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAG-AGLDGPEGDQGPQGPQ 624

Query: 511 GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG 559
           G  G   D    G  G PG PGP GD GLPG  G  G PG+  T    G
Sbjct: 625 GVPGTSKD----GQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSACQG 669


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  617 bits (1592), Expect = e-176
 Identities = 388/1004 (38%), Positives = 490/1004 (48%), Gaps = 168/1004 (16%)

Query: 41   NELCPKIRI----------GQDDLPGFDLISQFQVDKAASRRAIQRVVGSATLQVAYKLG 90
            N LCP +R+          G  ++ GFDL+  F V +   +R           Q +Y   
Sbjct: 220  NVLCPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKR-------ENGAQSSYVRM 272

Query: 91   NNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQT 150
             +      T +++P GLP+EY+F+TTFR   ++ K++W IWQ+ D     QV I+++G+ 
Sbjct: 273  GSFPVVQSTEDVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGEN 332

Query: 151  QSVVFSYKGLDGSLQTAAF--SNLSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKP 208
            ++V ++  G         F  S ++ LFD  WHK+ + ++  + +L +DC  +++LPI+ 
Sbjct: 333  KAVEYNAVGAMKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEE 392

Query: 209  RGPIDIDGFAVLGK-LADNPQVSVPFELQWMLIHCDPLRPRRETCHELPA---RIT---- 260
            R  IDI G  V+GK L D+  V + F+LQ ++I+CD      ETC ++P+   ++T    
Sbjct: 393  RENIDIQGKTVIGKRLYDS--VPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTE 450

Query: 261  ----------PSQTTDERG---------PPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP 301
                      P+  +++ G         P GE+G  G  GP G+PG  G  G  GP G P
Sbjct: 451  PPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAP 510

Query: 302  GPPGP----------AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGS 351
            GP G            GE G+ G+ G PG PG DG  G  G PG +G  G  GE G+ G 
Sbjct: 511  GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP 570

Query: 352  RGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLC 411
            +G P  G+PGPPG  G  GL GE G  G  G+ G RG  G PG PG  G  G        
Sbjct: 571  QGPP--GLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG-------- 620

Query: 412  PNACPPGRSGYPGLPGMRGHKGAKGEIGEPG----RQGHKGEEGDQGELGEVGAQGPPGA 467
                 PG SG  G  G +G  G  G  G PG    ++G KGE+G  G  G  GA GPPGA
Sbjct: 621  ----RPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGA 676

Query: 468  QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR-- 525
            +G  G  G  G  G +G RG  G+ GP G+PG  G QG  GPPG  GP G  G+ G    
Sbjct: 677  RGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGE 736

Query: 526  -GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV 584
             G PG PGP G TG PG DG +G PG PGTKGEPG+ G  G  G  GL G  G  G  G 
Sbjct: 737  IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR 796

Query: 585  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL-- 642
             GEKG  G PG PG  G  G+ G QG  GE+G  G +G  G +GE GP G PGLPG    
Sbjct: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856

Query: 643  --------------GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
                          G  G PGLPG PG  G PG  G +G  G PG KG++GA G  G AG
Sbjct: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 916

Query: 689  ERGELGDIGLPGPKGSAGNPGEPGLR---GPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745
              G  G +G PGP G  G+ G PGLR   G +G RG  G  G  G PGP G +G+ GA G
Sbjct: 917  NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976

Query: 746  L-----------PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794
            L           PG++G PG  P     K  C +V       +     + D GA G+PG 
Sbjct: 977  LPGPPGKGKDGEPGLRGSPG-LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGS 1035

Query: 795  P-----------GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 843
            P           GPPGP GPPG+ G PG    RGLPG  GP G  G  G  G+ GE+G  
Sbjct: 1036 PGSRGDPGIGVAGPPGPSGPPGDKGSPGS---RGLPGFPGPQGPAGRDGAPGNPGERGPP 1092

Query: 844  GPPG----------------------RGPNGLPGAIGLPGDPG----PASYGRNGRDGER 877
            G PG                       GP GLPG  G  GD G    P   G  G+ GE 
Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEA 1152

Query: 878  GPPGVAGIPGVPGPPGP------------------PGLPGFCEP 903
            GPPG+ G PG+ GP G                   PG+PGF  P
Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGP 1196



 Score =  539 bits (1388), Expect = e-153
 Identities = 321/727 (44%), Positives = 373/727 (51%), Gaps = 74/727 (10%)

Query: 249  RETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP------PG 302
            +E  H  P            G PG  GPPG  G PG+ G  G DG+RG KG       PG
Sbjct: 905  QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 964

Query: 303  PPGPAGEPGKPGAPGKPGT--PGADGLTGPDGSPGSIGSK-------------------- 340
            P GP G+PG PG PG PG    G  GL G  G PG +G+K                    
Sbjct: 965  PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVK 1024

Query: 341  ---GQKGEPGVPGSRGFPGRGIPGPPGP---------PGTAGLPGELGRVGPVGDPGRRG 388
               G  G PG PGSRG PG G+ GPPGP         PG+ GLPG  G  GP G  G  G
Sbjct: 1025 GDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPG 1084

Query: 389  PPGPPGPPGPRGTIGF-HDGD------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 441
             PG  GPPG  G       GD       +C N CPPG    PGLPG+ G KG KG  G+P
Sbjct: 1085 NPGERGPPGKPGLSSLLSPGDINLLAKDVC-NDCPPGP---PGLPGLPGFKGDKGVPGKP 1140

Query: 442  GR---QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 498
            GR   +G KGE G  G  G  G  GP G+QG RG  G VG KG++G  G+ G  GP G P
Sbjct: 1141 GREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNP 1200

Query: 499  GAPGDQ---GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 555
            G PG     G  GPPG  G  G  G  G +G  GLPG  G+ G  G DG+ G PG PG  
Sbjct: 1201 GPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA 1260

Query: 556  GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK---PGQMGNSGKPGQQGPP 612
            GEPG PGP G  G  G  G  G  GA G  GE G+ G PG+   PG+ G++G  G QGP 
Sbjct: 1261 GEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ 1320

Query: 613  GEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEP 672
            G  GP G  G PGS GE GP G+PG  G  G  GSPGLPG  GP G PG  G++GV G+ 
Sbjct: 1321 GPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380

Query: 673  GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPE---GSRGLPGVEGPR 729
            G  G+ G  G +GE G+ G  GD G PG KG  G+PG PG +G     G +GLPG  GP 
Sbjct: 1381 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440

Query: 730  GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL--KRPDSG 787
            GPPGP          G PG  G  G +P+ + ++++    + +      A L  + P + 
Sbjct: 1441 GPPGP---------PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY 1491

Query: 788  ATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 847
                 GRPGPPGPPG  G  G  G MG  G PG  G  G  G  GPKG+ G KG+ G PG
Sbjct: 1492 MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPG 1551

Query: 848  RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 907
             G  G  G  G+PG PG   Y ++G  G  GP G  G  G PG PGPPG PG C+P+ C 
Sbjct: 1552 VGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCA 1611

Query: 908  MQAGQRA 914
              A   A
Sbjct: 1612 YFASLAA 1618



 Score =  523 bits (1346), Expect = e-148
 Identities = 311/730 (42%), Positives = 360/730 (49%), Gaps = 94/730 (12%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P     + G  GEQG PGP G  G PG  G  G  GP+G  GPPG  G  GK G  G PG
Sbjct: 646  PGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG 705

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVG 379
             PG  GL GP G PG  G  G  G PG+PG  GFPG+ G PGP GPPG  G  G  G  G
Sbjct: 706  IPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPG 765

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G+PG RG  G PG PG RG IG      L       G +G PG PG  G +G KG+ G
Sbjct: 766  TKGEPGERGEDGLPGKPGLRGEIG---EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG 822

Query: 440  EPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGI-------TGIVGDKGEKGARGLDGEP 492
            E G  G  G +GD+GE GE G  GPPG  G   +        G  G KGEKG  GL GEP
Sbjct: 823  EKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEP 882

Query: 493  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP---------GPKGDTGLPGV- 542
            G QG PG  G QG  GPPG  G +G  GA GA G PG P         GP G  G PG+ 
Sbjct: 883  GLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942

Query: 543  --------------DGRDGIPGMPGTKGEPGKPGPP--------GDAGLQGLPGVPGIPG 580
                           G +G PG  G +G+PG PG P        G+ GL+G PG+PG  G
Sbjct: 943  GTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLG 1002

Query: 581  AKG-----------------VAGEKGSTGAPGKPGQMGN-----SGKPGQQGPPGEVGPR 618
             K                  V G++G+ G PG PG  G+     +G PG  GPPG+ G  
Sbjct: 1003 TKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSP 1062

Query: 619  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL---------------------PGPP 657
            G +GLPG  G  GP G  G PG  G  G PG PGL                     PGPP
Sbjct: 1063 GSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP 1122

Query: 658  GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGN---PGEPGLR 714
            GLPG+ G +G  G PG  G +G  G++GEAG  G  G  G+ GP+GS G     GE G +
Sbjct: 1123 GLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQK 1182

Query: 715  GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHF 774
            G +G  G+PG  GP G PGP G  G  GA G PG+QG PG+           +  I    
Sbjct: 1183 GDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEE 1242

Query: 775  AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK 834
             +     K    G  G  G PG PGP G  G  GF G  G  G PG +G  GA+GL G +
Sbjct: 1243 GKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 1302

Query: 835  GDLGEKGERGPPG----RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVP 889
            G  G+ G+ GP G    +GP G PG  G PG PG P   G  G+ G +G  G  G+PG  
Sbjct: 1303 GLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFL 1362

Query: 890  GPPGPPGLPG 899
            GP GPPG PG
Sbjct: 1363 GPRGPPGEPG 1372



 Score =  521 bits (1342), Expect = e-147
 Identities = 316/737 (42%), Positives = 360/737 (48%), Gaps = 116/737 (15%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGP------------PGVPGIDGIDGDRGPKGPPGP 303
            P +  P   T   G  G  GPPGPPG             PG PG+ G  G++G  G PG 
Sbjct: 740  PGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGE 799

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR------ 357
             G AG PG PG PG  G  G  G  G  G PG  G +G+KGE G  G  G PG       
Sbjct: 800  KGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTP 859

Query: 358  --GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC 415
               +PG  GP G  G PG  G  G  G PG  GP GP GPPG +G  G H       N  
Sbjct: 860  HPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 919

Query: 416  PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE---GDQGELGEVGAQGPPGAQGLRG 472
             PG  G PG  G  G  GA G  G PG+ G +GE+   G++G  G VG +G PGA GL G
Sbjct: 920  APGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPG 979

Query: 473  ITGIVGDKGEKGARGLDGEPGP--------------------------QGLPGAPGDQGQ 506
              G  G  GE G RG  G PGP                          +G PG PG  G 
Sbjct: 980  PPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGS 1038

Query: 507  R--------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            R        GPPG +GP GD+G+ G+RG+PG PGP+G        GRDG PG PG +G P
Sbjct: 1039 RGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA------GRDGAPGNPGERGPP 1092

Query: 559  GKPG-----PPGDAGL----------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 603
            GKPG      PGD  L           G PG+PG+PG KG  G  G  G  G  G+ G +
Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEA 1152

Query: 604  GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 663
            G PG  GPPG  GP+G QG  G+ GE+G  G  G PG  G +G PG PG PG  G+ G  
Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212

Query: 664  GDRGVVGEP---GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 720
            G  G+ G P   GP G QG SG  G  GE G+ G  G PGP G  G  GEPGL GPEG+R
Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272

Query: 721  GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR----APTDQHIKQVCMRVIQEHFAE 776
            G PG +G  G  G  G +GE GA GLPG +G PG+     PT     Q            
Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG----------- 1321

Query: 777  MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP------------ 824
                  R   G  G PG PG PGP G PG+ G  G+ G  GLPG  GP            
Sbjct: 1322 -----PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 1376

Query: 825  PGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGV 882
            PG  G+ G  G+ G KGERG PG +G  G PG  G PGDPG P   G  G  G +G PG 
Sbjct: 1377 PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGE 1436

Query: 883  AGIPGVPGPPGPPGLPG 899
             G  G PGPPG PG PG
Sbjct: 1437 NGPVGPPGPPGQPGFPG 1453



 Score =  506 bits (1302), Expect = e-143
 Identities = 302/693 (43%), Positives = 359/693 (51%), Gaps = 81/693 (11%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
            RGP G  G PGPPG  G PG+ G  G++G +G  G  G  G PGKPG  G+ G PG  G+
Sbjct: 568  RGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV 627

Query: 328  TGPDGSPGSIG-------------SKGQKGEPGVPGSRGFPGRGIPGPP----------- 363
             GP G  G +G              +G KGE G PG RG   +G PGPP           
Sbjct: 628  AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGH--QGAPGPPGARGPIGPEGR 685

Query: 364  -GPPGTAGLPGELGRVGPVGDP---GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP--P 417
             GPPG  GL G+ G +GP G P   G +GPPGPPG PGP G           P   P  P
Sbjct: 686  DGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPG-----------PGGSPGLP 734

Query: 418  GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIV 477
            G  G+PG PG  G  G  G+ G  G  G  G +G+ GE GE G  G PG +G  G  G+ 
Sbjct: 735  GEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLA 794

Query: 478  GDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDT 537
            G  GEKG  GL G PG  G+ G  GDQG++G  G  G KGDRG +G  G  G PG  G T
Sbjct: 795  GRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 854

Query: 538  GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGST 591
             L     R  +PG  G KGE G PG PG+ GLQG P      G  G PGAKG  G  G+ 
Sbjct: 855  SLFTPHPR--MPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 912

Query: 592  GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGELGPVGSPGLPGKLGSLGSP 648
            GA G PG  G+ G PG  GPPG VG  G +G P   G RGE G  G  G PG +G  G P
Sbjct: 913  GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972

Query: 649  GLPGLPGPP--GLPGMKGDRGVVGEPGPKGEQGASGEE--------GEAGERGELGDIGL 698
            G PGLPGPP  G  G  G RG  G PGP G + A G+         G    +G+ G  G+
Sbjct: 973  GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI 1032

Query: 699  PGPKGSAGNP-----GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 753
            PG  GS G+P     G PG  GP G +G PG  G  G PGP+G  G  GA G PG +GPP
Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPP 1092

Query: 754  GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQM 813
            G+      +    + ++ +   ++         G  GLPG  G  G PG PG  G  G+ 
Sbjct: 1093 GKPGLSSLLSPGDINLLAK---DVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKK 1149

Query: 814  GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNG 872
            G  G PG+ GPPG  G +G +G+ G  GE G  G +G  G+PG +G PG+PGP   G +G
Sbjct: 1150 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPP--GADG 1207

Query: 873  RDGERGPPGVAGIPGVPGPPGP------PGLPG 899
              G  GPPG+ G PG  GPPGP      PG+PG
Sbjct: 1208 IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240



 Score =  291 bits (746), Expect = 1e-78
 Identities = 191/465 (41%), Positives = 221/465 (47%), Gaps = 58/465 (12%)

Query: 492 PGPQGLPGAPGDQ--GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 549
           P P   P  PG +  G       + P G++G  G  G  GLPGPKGD G     G  G P
Sbjct: 454 PPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIG---AIGPVGAP 510

Query: 550 GMPGTKGEPG----KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN--- 602
           G  G KG+ G      G  G+ G  GLPG PG  G+KG+ GE G  G PG PG++G    
Sbjct: 511 GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP 570

Query: 603 SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 662
            G PG  GPPG VG  G QG  G +G  G  G  GL G  G  G  G  G PGP G+ G 
Sbjct: 571 QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP 630

Query: 663 KGDRGVVGEPGPKGEQGA----SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 718
           +G++G VG  GP G  G+     G +GE G  G  G  G PGP G+ G  G  G  GP G
Sbjct: 631 QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690

Query: 719 SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 778
            +GL G +G  GPPG  G+ G QG  G PGV GPPG   +                 E+ 
Sbjct: 691 LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLP------------GEIG 738

Query: 779 ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG------------------ 820
              K    G TG PG+ GP GPPGPPG  G PG+ G  GLPG                  
Sbjct: 739 FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG 798

Query: 821 ------IKGPPGALGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGPASY-- 868
                 + G PG  G+RG KGD GEKGE G PG    RG  G  G  G PG PG  S   
Sbjct: 799 EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFT 858

Query: 869 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
                 GE+GP G  G PG+PG PG  G PG   P   T   G +
Sbjct: 859 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903



 Score =  241 bits (614), Expect = 3e-63
 Identities = 153/407 (37%), Positives = 182/407 (44%), Gaps = 100/407 (24%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
            +G PG++GPPGP GP G+PGI G +G  G  G PGPPG  G+ G+PG PG  G  G  G 
Sbjct: 1218 QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277

Query: 328  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----------GIPGPPGPPGTAGLPGELGR 377
             G  G  G+ G +G+ G  G+PG  G PG+          G  GP GPPG  G PG  G 
Sbjct: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 1337

Query: 378  VGPVGDPGRRG---------------PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 422
             GP G PG++G               P GPPG PG +G  G  +G P  P    PG  G 
Sbjct: 1338 PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG-KEGVPGKPGE--PGFKGE 1394

Query: 423  PGLPGMRGHKG---AKGEIGEPGRQGHKGEEG---DQGELGEVGAQGPPGAQGLRGITGI 476
             G PG++G KG    KG+ G+PG  GHKG  G    QG  GE G  GPPG  G  G  G+
Sbjct: 1395 RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 1454

Query: 477  VGDK--------------------------------------------GEKGARGLDGEP 492
             G+                                             G  G  GL G  
Sbjct: 1455 RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 1514

Query: 493  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG-----------LPGPKGDTG--- 538
            GP G PG PG  G  GP G  GPKG+RGA+G  G PG           +PG  G+ G   
Sbjct: 1515 GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1574

Query: 539  --LPGVDGRDGI------PGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
              LPG+ G  G       PG+PG  G PG+  P   A    L   PG
Sbjct: 1575 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621



 Score =  199 bits (507), Expect = 8e-51
 Identities = 124/318 (38%), Positives = 152/318 (47%), Gaps = 59/318 (18%)

Query: 610 GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL----PGMKGD 665
           G  GE+G  GP GLPG +G++G +         G +G+PG  G  G  G+     G KG+
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAI---------GPVGAPGPKGEKGDVGIGPFGQGEKGE 531

Query: 666 RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 725
           +G +G PGP G  G+ G  GE GE   LG+ GLPG  G  G  G PGL GP G  G PG+
Sbjct: 532 KGSLGLPGPPGRDGSKGMRGEPGE---LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGL 588

Query: 726 EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
           +G RG  G RG +GE+G  G PG  G                                  
Sbjct: 589 QGERGEKGTRGEKGERGLDGFPGKPGD--------------------------------- 615

Query: 786 SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG-IKGPPGALGLRGPKGDLGEKGERG 844
              TG  GRPGP G  GP GE G  G  G  G+PG +    G  G +G  G  G +G  G
Sbjct: 616 ---TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG 672

Query: 845 PPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 903
           PPG RGP G  G  G PG       G  G+ G+ GPPG+ G+ G+ GPPGPPG+PG   P
Sbjct: 673 PPGARGPIGPEGRDGPPG-----LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 904 ASCTMQAGQRAFNKGPDP 921
                  G+  F   P P
Sbjct: 728 GGSPGLPGEIGFPGKPGP 745


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  561 bits (1446), Expect = e-159
 Identities = 341/767 (44%), Positives = 397/767 (51%), Gaps = 149/767 (19%)

Query: 261  PSQTTDERGPPG---------EQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGP 306
            P QT  + G PG         + G PG PG PG PG+ GI G +G  G PG     PPGP
Sbjct: 655  PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG-------- 356
             G PG PG PG PGTPG  GL GP G PG  G KG+ G   PG PG  G PG        
Sbjct: 715  KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774

Query: 357  --RGIPGPPGPPGTAGL---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRG 400
              RG PGPPGPPG  GL   PG  G VGP G PG            +GPPGPPG PGP G
Sbjct: 775  GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834

Query: 401  TIGFHD-----GDPLCPNAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGD 452
              G H      GDP  P      PPG  G PG+PG  G  G  G  G PG+ G  G  G 
Sbjct: 835  QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894

Query: 453  QGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGE 512
            +GE+G +G  GPPG  G+ G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG 
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 513  AGP-----KGDRGAEGARGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKP 561
              P     KG++G  G  GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 562  GPPG------------DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG----- 604
            G PG            D G  G  GV G PG  GV G+ GS G PG+ G  G+ G     
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 605  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG  GP GE G  G  G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 665  ------DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG------ 712
                  + G+ GEPGP G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG      
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 713  -----LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 767
                 L G +G  GLPG+ G  G PGP+G   E G  G PGVQGPPG   +         
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP-------- 1243

Query: 768  RVIQEHFAEMAASLKRP--DSGATGLPGRPGPPGPPGPPG---------ENGFPGQMGIR 816
                        +L+ P  + G  G PGRPG PGP GPPG         E G PGQ G+ 
Sbjct: 1244 ----------GPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1293

Query: 817  GLPGIKGP---------PGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-- 864
            GLPG+KG          PG  GL G KGD G  G  G PG +GP+G+PG+ G  G+PG  
Sbjct: 1294 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1353

Query: 865  -----PASYGRNGRD----GERGPPGVAGIP---GVPGPPGPPGLPG 899
                 P   G +G+     G+ GPPG+ G P   G+PGP GP GLPG
Sbjct: 1354 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400



 Score =  546 bits (1408), Expect = e-155
 Identities = 325/698 (46%), Positives = 370/698 (53%), Gaps = 85/698 (12%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            GP G++G PGPPGPPG  G+DG+ G +G  GP G PGP G PG PG  G  G PG  G+ 
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIP 830

Query: 329  GPDGSPGSIGSKGQKGEPGVPG--------SRGFPG-RGIPGPPGPPGTAGLPGELGRVG 379
            GP G PG  G  G+KG+PG PG         RG PG  G PGP GPPG+ GLPG+ G  G
Sbjct: 831  GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G  G  G  GPPGPPGP G  G   G P        G  G PGLPG  G KG+KGE G
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG--DDGLQGQPGLPGPTGEKGSKGEPG 947

Query: 440  EPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG---LDGEPGP 494
             PG  G       G +GE GE G  G PG  G +G  G+ GD G+ G  G   L G PGP
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGP 1007

Query: 495  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI---------------PGLPGPKGDTGL 539
            +G PG PG  G  GPPG  G  GD G  G +G+               PGLPG KGD G 
Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067

Query: 540  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------LPGVPGIPGAKGVAGEKGSTGA 593
            PG+    G+PG+PG KGEPG PG PG+ G++G      LPG+PG PGAKG  G  G  G 
Sbjct: 1068 PGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126

Query: 594  PGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL 650
            PG PG  G SG PG  G PGE GP    G  G PG  GE G  G  G+PG  G  G PG 
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186

Query: 651  PGL--PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP 708
            PG   PGPPGLPG+ G +G  G PG  G  G  G +GE G  G  G  G PGP GS G  
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 709  -----GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIK 763
                 G PG +GP G  GLPG EGP G PG  G++GE+G  G PG+ G PG         
Sbjct: 1247 LEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG------ 1300

Query: 764  QVCMRVIQEHFAEMAASLKRPD-SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 822
                    +    +  +  RP  +G  G PG PG PG PG  G +G PG  G  G PG+ 
Sbjct: 1301 -------DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1353

Query: 823  GPPGALGLRGPKGD-LGEKGERGPPG-------------RGPNGLPGAIGLPGDPG---- 864
            GPPG  GL GP G  +  KG+ GPPG             +GP GLPG  G PGDPG    
Sbjct: 1354 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL 1413

Query: 865  PASYGRNGRDGERGPPGVAGIPGVPGPPGP---PGLPG 899
            P   G  GR G+ G PG  G  G+ GPPGP    G PG
Sbjct: 1414 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1451



 Score =  543 bits (1399), Expect = e-154
 Identities = 330/720 (45%), Positives = 374/720 (51%), Gaps = 85/720 (11%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPK---GPPGP 303
            P+ E    LP    P      +G  G +G  G PGPPG PG  G+DG  GPK   GP G 
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--------PGVPGSRGFP 355
            PGP G PG PG  G  G PG  G+ GP G PG  G  G+KG+        PG PG RG P
Sbjct: 807  PGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 356  G-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA 414
            G  G PGP GPPG+ GLPG+ G  G  G  G  G  GPPGPPGP G  G   G P     
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG- 923

Query: 415  CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRG 472
               G  G PGLPG  G KG+KGE G PG  G       G +GE GE G  G PG  G +G
Sbjct: 924  -DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 473  ITGIVGDKGE---KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI-- 527
              G+ GD G+    G  GL G PGP+G PG PG  G  GPPG  G  GD G  G +G+  
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 528  -------------PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQ---- 570
                         PGLPG KGD G PG+    G+PG+PG KGEPG PG PG+ G++    
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 571  --GLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPG 625
              GLPG+PG PGAKG  G  G  G PG PG  G SG PG  G PGE GP    G  G PG
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161

Query: 626  SRGELGPVGSPGLPGKLGSLGSPGLPGL--PGPPGLPGMKGDRGVVGEPGPKGEQGASGE 683
              GE G  G  G+PG  G  G PG PG   PGPPGLPG+ G +G  G PG  G  G  G 
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221

Query: 684  EGEAGERGELGDIGLPGPKGS-----AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 738
            +GE G  G  G  G PGP GS      G  G PG +GP G  GLPG EGP G PG  G++
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIK 1281

Query: 739  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD-SGATGLPGRPGP 797
            GE+G  G PG+ G PG                 +    +  +  RP  +G  G PG PG 
Sbjct: 1282 GEKGNPGQPGLPGLPGLKG-------------DQGPPGLQGNPGRPGLNGMKGDPGLPGV 1328

Query: 798  PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG-DLGEKGERGPPG--------- 847
            PG PG  G +G PG  G  G PG+ GPPG  GL GP G  +  KG+ GPPG         
Sbjct: 1329 PGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKG 1388

Query: 848  ----RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
                +GP GLPG  G PGDPG    P   G  GR G+ G PG  G  G+ GPPGP GL G
Sbjct: 1389 LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1448



 Score =  531 bits (1368), Expect = e-150
 Identities = 318/720 (44%), Positives = 362/720 (50%), Gaps = 98/720 (13%)

Query: 267  ERGPPGEQGPPGPPG-----------PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK--- 312
            ERGPPG  G PG PG           PPG  G  GI G  G  G PG PGP G+PG+   
Sbjct: 601  ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 313  -PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 371
             PG PG PG PG DG  G  G PG  G  G  G PG  G  G PG G+PGPPGP G  G+
Sbjct: 661  QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 720

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGH 431
            PG  G  G  G  G  GPPGPPG PGP+G  GF       P   PPG  G PG  G  G 
Sbjct: 721  PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGP 773

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE 491
            KG +G  G PG  G  G +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G 
Sbjct: 774  KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGP 832

Query: 492  PGPQGLPGAPGDQGQRGPPG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 549
             G  GL G PG++G  GPPG    GP G+RG+ G   IPG PGP G  G PG+ G+ G  
Sbjct: 833  IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG---IPGAPGPIGPPGSPGLPGKAGAS 889

Query: 550  GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 609
            G PGTKGE G  GPPG  G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 610  GPPGEV-----------------------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLG 646
            GPPG +                       GP+G QGLPG  G+ G  G PGLPG  G  G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 647  SPGLPGLPG---PPGLPGMKGD------RGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
            +PGLPG PG   PPGL G  GD      +GV G PGP G  G  G  G  G++G+ GD G
Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069

Query: 698  --------LPGPKG---------------SAGNPGEPGLRGPEGSRG---LPGVEGPRGP 731
                    LPGPKG               S G+PG PGL G  G++G   LPG  G  GP
Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129

Query: 732  PGPRGVQGEQGATGLPGVQGPPGRA--PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGAT 789
            PGP+G+ G  G  GLPG  GP G    P          +  Q+     A     P     
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 790  GLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRG 849
            G PG PG PG  G  G+ G PG  G  GLPG KG PG  G  G +G  G  G  GP   G
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249

Query: 850  PNGLPGAIGLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            P G PG  G PG PG          P + G  G  G  G PG+ G+PG+ G  GPPGL G
Sbjct: 1250 PKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1309



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 382
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 383 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 434
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 435 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 478
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 479 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 530 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 579
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 580 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 627
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 628 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 671
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 672 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 721
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 722 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 768
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 769 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 825 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 882
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 883 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  516 bits (1329), Expect = e-146
 Identities = 332/784 (42%), Positives = 377/784 (48%), Gaps = 155/784 (19%)

Query: 267  ERGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPPGPPG-----PAGEPGKPGAP 316
            ERG PG QGPPG PGPPG      PG  G  G+RG KG  GPPG     P G  G+PGAP
Sbjct: 372  ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 317  GKPGTPGADGL----------TGPDGSPGSIGSKGQKGEPGVPGSRGF------------ 354
            G PG PG  G            GP G PGS G KG +GE GV G +G             
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 355  -PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGRRGPPGPPGPPGPRGTIGF-- 404
             PG+ G+PG PGPPG+ G PG+ G        GP G PG  G PG PG PG +G  G   
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 405  ----------HDGDPLCPNAC----PPGRSGYPGLPGMRGHKGA---KGEIGEPGRQGHK 447
                        G P  P        PG+ G PGLPG +G  G    KGE G PG  G  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 448  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ------------ 495
            G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G  G+PG              
Sbjct: 612  GLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN 670

Query: 496  -------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548
                   GLPG PG  GQ G PG  G KG+ G  G  G+PG PGPKG  G+PG  G  G 
Sbjct: 671  PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGT 729

Query: 549  PGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 603
            PG  G +G PG PG PG  G     L G PG PG+PG KG  G KG  G PG PG  G +
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 604  GKPGQQGPPGEVGPRGP--------------QGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            G  G  GP G+VGP G               QG PG  G  GP+G PGL G  G  G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 650  LPGL--PGP------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
             PGL  PGP      PG+PG  G  G  G PG  G+ GASG  G  GE G +G  G PGP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 702  KGSAGNPGEPGLRGPEGSRGLPGVEGPR------------GPPGP--------RGVQGEQ 741
             G  G  G PGL+G +G +G PG+ GP             GPPGP        +G +GE 
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 742  GATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP 801
            G  G+PGV GP G                              D G  GL G+PG PGPP
Sbjct: 970  GLPGIPGVSGPKGYQGLP------------------------GDPGQPGLSGQPGLPGPP 1005

Query: 802  GPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLP 860
            GP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G  G PG+ G  GLPG  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 861  GDPGPASYGRNGRDGERGPPGVAGIPGVP---GPPGPPGLPGFCEPASCTMQAGQRAFNK 917
            GDPG +S G  G  G +G PG+ G PG P   G  G PGLPG         Q G   F  
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 918  GPDP 921
             P P
Sbjct: 1126 TPGP 1129



 Score =  511 bits (1315), Expect = e-144
 Identities = 306/688 (44%), Positives = 360/688 (52%), Gaps = 87/688 (12%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G  G  G PG PG PG PG DG+ G  GPKG PG     GE G PG PG PG PG  G
Sbjct: 559  DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 327  LTGPDG--SPGSIGSKG------QKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 378
              GP G   PG +G KG        G+PG+PG +G PG+ I   PG PG  G PG  G V
Sbjct: 619  PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-QPGKPGLPGNPGRDGDV 677

Query: 379  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 438
            G  GDPG  G PG PG PG +G  G     P      PPG  G+PG+PG  G  G  G I
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733

Query: 439  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 498
            G  G  G  G  G +GE G     GPPG  GL G  G +G KG++G  G  G PG  GL 
Sbjct: 734  GLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792

Query: 499  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G PG +G  GP G+ GP G  G  G     G+ GP G  G+PG  G+ G+ G+PG KG+P
Sbjct: 793  GLPGPKGDVGPNGQPGPMGPPGLPGI----GVQGPPGPPGIPGPIGQPGLHGIPGEKGDP 848

Query: 559  GKPG-----PPGDAGLQGLPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 610
            G PG     PPG+ G  G+PG PG    PG+ G+ G+ G++G PG  G+MG  G PG   
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG--- 905

Query: 611  PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-----LPGMKGD 665
            PPG +G  G  G+PG +G+ G  G PGLPG  G  GS G PGLPGPPG     L G KG+
Sbjct: 906  PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965

Query: 666  RGVVGEPG------PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 719
            +G  G PG      PKG QG  G+ G+ G  G+ G  G PGPKG+ G PG+PGL GP G 
Sbjct: 966  KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025

Query: 720  RG------LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEH 773
            +G       PG +G  GPPGP GV G+ G+ GLPG +G  G                   
Sbjct: 1026 KGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD------------------ 1067

Query: 774  FAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 833
                      P   + GLPG PGP G PG PG  G PG  G  G PG+ G PG  G +G 
Sbjct: 1068 ----------PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 834  KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP 892
             G  G  G  GPPG +G +G PG  GLPG+PGP   G           G  G PG PG  
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG-----------GHPGQPGPPGEK 1166

Query: 893  GPPGLPGFCEPASCTMQAGQRAF-NKGP 919
            G PG  G   PA    + GQ  F N GP
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194



 Score =  508 bits (1308), Expect = e-143
 Identities = 330/814 (40%), Positives = 379/814 (46%), Gaps = 190/814 (23%)

Query: 264 TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
           T  ERG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 324 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP----- 366
             G+ GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP     
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 367 -----------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG-- 403
                      G  GLPG+    GP G PG RGPPGPP          G PG RG  G  
Sbjct: 247 QKRPIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 404 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------I 438
             +G P  P    PG  GYPG PG  G KG KG+                         I
Sbjct: 304 GENGQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 439 GEPGRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR---------- 486
           G PG  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG            
Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 487 -GLDGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI-------- 527
            GLDG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+        
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTC 481

Query: 528 -----PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG-- 580
                 G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG  
Sbjct: 482 FNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 581 -----------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629
                        G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601

Query: 630 LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS-- 681
            GP G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +  
Sbjct: 602 RGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 682 --GEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 739
             G+ G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+    
Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK---- 715

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG------ 793
                G PG+ GPPG   T   I                  L+ P  G  G PG      
Sbjct: 716 -----GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPG 752

Query: 794 --RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG- 847
              PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G 
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 848 -----------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPG 887
                       GP G+PG IG P         GDPGP      G  GERG PG+ G PG
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 888 VPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
             GPPG PGLPG    +      G+      P P
Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 313
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 314 ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 366
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 404
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 405 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 448
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 449 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 494
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 495 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 550
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 551 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 601
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 602 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 641
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 642 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 698
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 699 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 756
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 806
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 807 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 864
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 865 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 915
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 916 NKGPDP 921
              P P
Sbjct: 949 PGPPGP 954



 Score =  459 bits (1180), Expect = e-129
 Identities = 276/631 (43%), Positives = 322/631 (51%), Gaps = 115/631 (18%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 317
            ERG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 318  ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 356
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 357  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 405
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 451
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 511
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 512  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 569
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 570  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG---PRGPQGLPGS 626
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  G   P GP GLPG+
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277

Query: 627  ------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG------P 674
                  +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG      P
Sbjct: 1278 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337

Query: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPGVEGPRG 730
             G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG +GP+G
Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1397

Query: 731  PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 790
             PGP G  G+ G  GLPG  G  GR                               G  G
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGR------------------------------KGDPG 1427

Query: 791  LPGRP------GPPGPPGPPGENGFPGQMGI 815
            LPG+P      GPPGP G  G  G PG   +
Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  457 bits (1177), Expect = e-128
 Identities = 280/643 (43%), Positives = 327/643 (50%), Gaps = 124/643 (19%)

Query: 266  DERGPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEP 310
            D  GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G P
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP 913

Query: 311  GKPGAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPG 350
            G+ G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG 973

Query: 351  SRGFPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH- 405
              G  G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG   
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 406  -------DGDPLCPNACPPGRSGYPGLPGMRGHK--------------GAKGEIGEPGRQ 444
                   +G P  P+   PG+ G PGLPG +G K              G KGE G PG  
Sbjct: 1034 FPGPQGVEGPP-GPSGV-PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091

Query: 445  GHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ 504
            G+ G +G  G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 505  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV--DGRDGIPGMPGTKGEPGKPG 562
            G  G PG+ GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 563  PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE---VGPRG 619
             PG+ GL G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG     GP G
Sbjct: 1212 IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPGPEG 1270

Query: 620  PQGLPGS------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEP- 672
            P GLPG+      +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G P 
Sbjct: 1271 PPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG 1330

Query: 673  -----GPKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLP 723
                 GP G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLP
Sbjct: 1331 FPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLP 1390

Query: 724  GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 783
            G +GP+G PGP G  G+ G  GLPG  G  GR                            
Sbjct: 1391 GPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR---------------------------- 1422

Query: 784  PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 826
               G  GLPG+PG  G  GPPG +         GL G  GPPG
Sbjct: 1423 --KGDPGLPGQPGTRGLDGPPGPD---------GLQGPPGPPG 1454



 Score =  409 bits (1051), Expect = e-114
 Identities = 246/578 (42%), Positives = 286/578 (49%), Gaps = 96/578 (16%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPG---IDGIDGDRGPKGPPGPPGPAGEPG 311
            LP +   S     +G  G  GPPGPPGP G+PG   + G+ GD G +G PG PGP GE G
Sbjct: 882  LPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 312  KPGAPGKPGTPGA-----------DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GI 359
              G PG PG PG             G  G  G PG  G KG +G PG PG  G  G+ G+
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 360  PGPPGPPGTAGLPGELGRVGP------VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413
            PGPPGP G  GLPG+ G +GP      +GD G  GP G  GPPGP G  G   G P  P 
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPG-QPGSPGLPG 1060

Query: 414  -------------ACP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE 458
                           P  PG  G PGLPG  G+ G KG +G+PG  G  G  G +G+ G 
Sbjct: 1061 QKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGL 1120

Query: 459  VGAQGPPGAQGLRGITGIVGDKG---------------------EKGARGLDGEPGPQGL 497
             G  G PG  G +GI+G  G+ G                     EKG  G DG PGP G 
Sbjct: 1121 PGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQ 1180

Query: 498  PGAPGDQGQRGP-----PGEAGPKGDRGAEGARGIPGLPGPKGDTGL---PGVDGRDGIP 549
             G PG  G   P     PG +G KGD G  G  G PGLPGPKG+ G    PGV G  G P
Sbjct: 1181 KGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPP 1240

Query: 550  GMPGT-----KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG--------- 595
            G PG      KG PG  GPPG  GL G  G PG+PG  G+ GEKG+ G PG         
Sbjct: 1241 GSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1300

Query: 596  ---KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 652
                PG  GN G+PG  G  G+ G  G  G PG +G  G  GS G  G+ G +G PG PG
Sbjct: 1301 DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPG 1360

Query: 653  LPGP-------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP 699
            LPGP             PG+PG  G +G+ G  GP+G  G +G  G+ G  G  G  G  
Sbjct: 1361 LPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG 1420

Query: 700  GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV 737
            G KG  G PG+PG RG +G  G  G++GP GPPG   V
Sbjct: 1421 GRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  380 bits (977), Expect = e-105
 Identities = 247/584 (42%), Positives = 288/584 (49%), Gaps = 105/584 (17%)

Query: 417 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI 476
           PG  G+PGLPG  G +G  G  G+ G  G  G  G +G  G  G  G PG  GL G+ G 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH 112

Query: 477 VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 536
            G  G +G  G +G  G +G PG+PG  G +GPPG  G  G +G  G+  +  LPGPKG+
Sbjct: 113 DGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172

Query: 537 TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP-----------GAKGVA 585
              PG  G  GI G+PG  G PG  GPPG  GL G PG PG+P           G KG  
Sbjct: 173 ---PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229

Query: 586 GEKGSTGAPGKPGQM-------------GNSGKPGQQGPPGEVGPRGPQGLP----GSRG 628
           GE+G  G PG PGQ+             G+ G PG +GPPG  G RGP G P    G +G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP------GMKGDRGVVGEPGPK------- 675
           E G  G  G PGK G  G PG+PGLPG PG P      G KG +G  G PGP        
Sbjct: 290 EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRP 349

Query: 676 ------GEQGASGEEGEAGERGELGDIGLPGPKGSAGNP-----GEPGLRGPEGSRGLPG 724
                 GE+G  G  G  GE+GE G  G+ GP G  G P     G PG  G  G RG  G
Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG 409

Query: 725 VEGPRG--PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM------------RVI 770
            EGP G   PGP G+ G+ GA GLPG  GP G  P      ++C             + +
Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGPPGPPGSPGDKGL 467

Query: 771 QEHFAEMAASLKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQ---------MG 814
           Q    E      + D       +G +G PG+PG PG PGPPG  GFPGQ          G
Sbjct: 468 Q---GEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG 524

Query: 815 IRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR----GPNGLPGAIGLP 860
            +GLPGI G PGA G  G KG+           G+KGE G PG     G  G PG  GLP
Sbjct: 525 PKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584

Query: 861 GDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 903
           G PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  348 bits (892), Expect = 2e-95
 Identities = 224/551 (40%), Positives = 262/551 (47%), Gaps = 123/551 (22%)

Query: 474 TGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP 533
           +GI G+KGE+G  GL+G PG  G PG  G  G RG  G+ G  G  G +G RG PGLPG 
Sbjct: 41  SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100

Query: 534 KGDTGLPGVDGRDG------IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587
            G  GLPG+ G DG      IPG  GTKGE G PG PG  GLQG PG PGIPG KG  G 
Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 588 KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL-- 645
              +  PG  G  G  G PG QG PG  G  GP G PG  G +GP G PGLPG  G++  
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 646 ---------GSPGLPGLPGPPGL----------------PGMKGDRGVVGEPG------- 673
                    G  GL G PGPPG                  G+ GDRG  G PG       
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 674 PKGEQGASGEEGEAGERGEL---GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 730
           P GE+G  GE+GE G+RG+    G+ G PG  G  G+PG PG  G +G +G  G  GP G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 731 PPG---PR----------------GVQGEQGATGLPGVQGPPG-RAPTDQHIKQ------ 764
           PPG   PR                G+ GE+G  G PG+QGPPG   P    +        
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 765 -VCMRVIQEHFAEMAASLKRP-----DSGATGLPG----------------RPGPPGPPG 802
               R  +        S+  P       GA GLPG                 PGPPGPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 803 PPGENGFPGQMGIR----------------------GLPGIKGPPGALGLRGPKGDLGEK 840
            PG+ G  G+ G++                      GLPG+ GPPG+LG  G KG+ G+ 
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 841 GERGPPGRGPNGLPGAIGLPGDPGPASY--------GRNGRDGERGPPGVAGIPGVPGPP 892
           G  GP  +G  G+PGA G PG PG            G  G  GE G PG  G+PG+PG P
Sbjct: 521 GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 893 GPPGLPGFCEP 903
           G  GLPG   P
Sbjct: 579 GQDGLPGLPGP 589



 Score =  297 bits (761), Expect = 3e-80
 Identities = 191/453 (42%), Positives = 225/453 (49%), Gaps = 80/453 (17%)

Query: 508 GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 567
           G  GE G +G  G EG  G+PG PGP+G  G  G  G DGIPG PG KG  G PG     
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG----- 96

Query: 568 GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK---PGQQGPPGEVGPRGPQGLP 624
               LPG PG PG  G+ G  G+ G  G PG  G  G+   PG  G PG  GP GP G+P
Sbjct: 97  ----LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 625 GSRGE---------LGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPGMKGDRGVVGEP 672
           G +GE          GP G+PG PG  G  G PG  G+P   GPPG PG+ G  G  G P
Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 673 GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG----------NPGEPGLRGPEGSRGL 722
           GPKG  G +  +G  GE+GE G  G PGP G               G+ GL G  G  G 
Sbjct: 213 GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 723 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
           PG+ GP GPPG  G +GE+G  G PG +G PG                           K
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPG---------------------------K 302

Query: 783 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG----PPGALGLRGPKGDL- 837
             ++G  G+PG PG PG PG PG +G  GQ G  G PG  G     PG     G KG++ 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 838 -----GEKGERGPPG-RGPNGLPGAIG--LPGDPGPASY-GRNGRDGERGPPGVA--GIP 886
                GEKGERG PG +GP GLPG  G  + G PGP  + G  G+ G+ GPPG++  G P
Sbjct: 363 LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 887 GVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G+ G PG PGLPG   PA   +         GP
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score =  207 bits (527), Expect = 4e-53
 Identities = 132/325 (40%), Positives = 154/325 (47%), Gaps = 79/325 (24%)

Query: 624 PGSR----GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 679
           PGS+    G  G  G  G PG  G  G PG PG  GPPG  G KGD G+ G PGPKG +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 680 ASGEEGEAGERG---ELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736
             G  G  G  G     G  G PGP+G  G  G  G RG  GS G PG++GP GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 737 VQGEQGA---TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793
           ++GE G+   + LPG +G PG                                G  G+ G
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGY------------------------------PGPPGIQG 183

Query: 794 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL--RGPKGDLGEKGERGPPG---- 847
            PGP G PGP G  G PG MG  G PG+ GP G +GL  +GPKG+ GE+G +GPPG    
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 848 ----------------------RGPNGLPGAIGLPGDPG-----------PASYGRNGRD 874
                                 RGP G PG  G PG PG           P   G+ G+D
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 875 GERGPPGVAGIPGVPGPPGPPGLPG 899
           GE G PG+ G+PG PG PG PG  G
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDG 328


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  560 bits (1443), Expect = e-159
 Identities = 336/736 (45%), Positives = 385/736 (52%), Gaps = 121/736 (16%)

Query: 261  PSQTTDERGPPG---------EQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGP 306
            P QT  + G PG         + G PG PG PG PG+ GI G +G  G PG     PPGP
Sbjct: 655  PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG-------- 356
             G PG PG PG PGTPG  GL GP G PG  G KG+ G   PG PG  G PG        
Sbjct: 715  KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774

Query: 357  --RGIPGPPGPPGTAGL---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRG 400
              RG PGPPGPPG  GL   PG  G VGP G PG            +GPPGPPG PGP G
Sbjct: 775  GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834

Query: 401  TIGFHD-----GDPLCPNAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGD 452
              G H      GDP  P      PPG  G PG+PG  G  G  G  G PG+ G  G  G 
Sbjct: 835  QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894

Query: 453  QGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGE 512
            +GE+G +G  GPPG  G+ G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG 
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 513  AGP-----KGDRGAEGARGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKP 561
              P     KG++G  G  GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 562  GPPG------------DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG----- 604
            G PG            D G  G  GV G PG  GV G+ GS G PG+ G  G+ G     
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 605  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG  GP GE G  G  G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 665  ------DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG------ 712
                  + G+ GEPGP G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG      
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 713  -----LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 767
                 L G +G  GLPG+ G  G PGP+G   E G  G PGVQGPPG   +         
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP-------- 1243

Query: 768  RVIQEHFAEMAASLKRP--DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP 825
                        +L+ P  + G  G PGRPG  G PGP G  G PG  GI+G  G  G P
Sbjct: 1244 ----------GPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQP 1293

Query: 826  GALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVA 883
            G  GL G KGD G  G +G PGR G NG+ G  GLPG PG P   G +G  G  GP G  
Sbjct: 1294 GLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE- 1352

Query: 884  GIPGVPGPPGPPGLPG 899
              PG+ GPPGPPGLPG
Sbjct: 1353 --PGLIGPPGPPGLPG 1366



 Score =  541 bits (1394), Expect = e-153
 Identities = 330/716 (46%), Positives = 372/716 (51%), Gaps = 74/716 (10%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPK---GPPGP 303
            P+ E    LP    P      +G  G +G  G PGPPG PG  G+DG  GPK   GP G 
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--------PGVPGSRGFP 355
            PGP G PG PG  G  G PG  G+ GP G PG  G  G+KG+        PG PG RG P
Sbjct: 807  PGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 356  G-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA 414
            G  G PGP GPPG+ GLPG+ G  G  G  G  G  GPPGPPGP G  G   G P     
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG- 923

Query: 415  CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRG 472
               G  G PGLPG  G KG+KGE G PG  G       G +GE GE G  G PG  G +G
Sbjct: 924  -DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 473  ITGIVGDKGE---KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
              G+ GD G+    G  GL G PGP+G PG PG  G  GPPG  G  GD G  G +G+ G
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 530  LPGPKGDTGLPGVDGRDGIPGMPGTKGEP-----GKPGPPGDAGLQGLPGVPGIPGAKGV 584
             PGP   +G+PG  G  G+PG  G KG+P     G PG PG  G  GLPG PG PG KG 
Sbjct: 1043 PPGP---SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGS 1099

Query: 585  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR---GPQGLPGSRGELGPVGS---PGL 638
             G+ G  G PG PG  G  G PG  G PG  GP+   GP G PG  GE GPVG    PG 
Sbjct: 1100 VGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 639  PGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGL 698
            PG  G  G PG  G+PGP G  G  G  G  G PGP G  G SG++G+ G  G  G+ GL
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 699  PGPKGSAGNPGEPGLRGPEGSRGLPG--VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 756
            PGPKG  G  G PG++GP G  G PG  +EGP+G PGP+G  G  G  GLPG +GPPG  
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPG-L 1277

Query: 757  PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP------GPPGPPGENGFP 810
            P +  IK       Q     +     + D G  GL G PG P      G PG PG  GFP
Sbjct: 1278 PGNGGIKGEKGNPGQPGLPGLPG--LKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1335

Query: 811  GQMGIRGLPGIKGPPGALGLRGPKGDLG----------EKGERGPPG------------- 847
            G  G  G+PG  GP G  GL GP G  G           KG+ GPPG             
Sbjct: 1336 GMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP 1395

Query: 848  RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            +GP GLPG  G PGDPG    P   G  GR G+ G PG  G  G+ GPPGP GL G
Sbjct: 1396 QGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1451



 Score =  530 bits (1366), Expect = e-150
 Identities = 312/691 (45%), Positives = 352/691 (50%), Gaps = 105/691 (15%)

Query: 267  ERGPPGEQGPPGPPG-----------PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK--- 312
            ERGPPG  G PG PG           PPG  G  GI G  G  G PG PGP G+PG+   
Sbjct: 601  ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 313  -PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 371
             PG PG PG PG DG  G  G PG  G  G  G PG  G  G PG G+PGPPGP G  G+
Sbjct: 661  QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 720

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGH 431
            PG  G  G  G  G  GPPGPPG PGP+G  GF       P   PPG  G PG  G  G 
Sbjct: 721  PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGP 773

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE 491
            KG +G  G PG  G  G +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G 
Sbjct: 774  KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGP 832

Query: 492  PGPQGLPGAPGDQGQRGPPG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 549
             G  GL G PG++G  GPPG    GP G+RG+ G   IPG PGP G  G PG+ G+ G  
Sbjct: 833  IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG---IPGAPGPIGPPGSPGLPGKAGAS 889

Query: 550  GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 609
            G PGTKGE G  GPPG  G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 610  GPPGEV-----------------------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLG 646
            GPPG +                       GP+G QGLPG  G+ G  G PGLPG  G  G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 647  SPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706
            +PGLPG PG  G PG+KG  G +G PGP   QG  G  G +G  G+ G  GLPG KG  G
Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGP---QGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 707  NPGE-----PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQH 761
            +PG      PGL GP+G  GLPG       PG  G++G  G  GLPG+ G PG       
Sbjct: 1067 DPGISSIGLPGLPGPKGEPGLPGY------PGNPGIKGSVGDPGLPGLPGTPGA------ 1114

Query: 762  IKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP------------PGPPGENGF 809
                                 +   G  G PG PGPPGP            PG PG  G 
Sbjct: 1115 ---------------------KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153

Query: 810  PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASY 868
             G  G  G PG KG PG  G+ GP G  GE G+ G    GP GLPG  G  GD G P   
Sbjct: 1154 GGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 869  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            G  G  G +G PG  G PGV GPPGPPG PG
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 382
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 383 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 434
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 435 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 478
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 479 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 530 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 579
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 580 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 627
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 628 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 671
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 672 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 721
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 722 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 768
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 769 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 825 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 882
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 883 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  516 bits (1329), Expect = e-146
 Identities = 332/784 (42%), Positives = 377/784 (48%), Gaps = 155/784 (19%)

Query: 267  ERGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPPGPPG-----PAGEPGKPGAP 316
            ERG PG QGPPG PGPPG      PG  G  G+RG KG  GPPG     P G  G+PGAP
Sbjct: 372  ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 317  GKPGTPGADGL----------TGPDGSPGSIGSKGQKGEPGVPGSRGF------------ 354
            G PG PG  G            GP G PGS G KG +GE GV G +G             
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 355  -PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGRRGPPGPPGPPGPRGTIGF-- 404
             PG+ G+PG PGPPG+ G PG+ G        GP G PG  G PG PG PG +G  G   
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 405  ----------HDGDPLCPNAC----PPGRSGYPGLPGMRGHKGA---KGEIGEPGRQGHK 447
                        G P  P        PG+ G PGLPG +G  G    KGE G PG  G  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 448  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ------------ 495
            G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G  G+PG              
Sbjct: 612  GLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN 670

Query: 496  -------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548
                   GLPG PG  GQ G PG  G KG+ G  G  G+PG PGPKG  G+PG  G  G 
Sbjct: 671  PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGT 729

Query: 549  PGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 603
            PG  G +G PG PG PG  G     L G PG PG+PG KG  G KG  G PG PG  G +
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 604  GKPGQQGPPGEVGPRGP--------------QGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            G  G  GP G+VGP G               QG PG  G  GP+G PGL G  G  G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 650  LPGL--PGP------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
             PGL  PGP      PG+PG  G  G  G PG  G+ GASG  G  GE G +G  G PGP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 702  KGSAGNPGEPGLRGPEGSRGLPGVEGPR------------GPPGP--------RGVQGEQ 741
             G  G  G PGL+G +G +G PG+ GP             GPPGP        +G +GE 
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 742  GATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP 801
            G  G+PGV GP G                              D G  GL G+PG PGPP
Sbjct: 970  GLPGIPGVSGPKGYQGLP------------------------GDPGQPGLSGQPGLPGPP 1005

Query: 802  GPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLP 860
            GP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G  G PG+ G  GLPG  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 861  GDPGPASYGRNGRDGERGPPGVAGIPGVP---GPPGPPGLPGFCEPASCTMQAGQRAFNK 917
            GDPG +S G  G  G +G PG+ G PG P   G  G PGLPG         Q G   F  
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 918  GPDP 921
             P P
Sbjct: 1126 TPGP 1129



 Score =  508 bits (1308), Expect = e-143
 Identities = 330/814 (40%), Positives = 379/814 (46%), Gaps = 190/814 (23%)

Query: 264 TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
           T  ERG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 324 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP----- 366
             G+ GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP     
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 367 -----------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG-- 403
                      G  GLPG+    GP G PG RGPPGPP          G PG RG  G  
Sbjct: 247 QKRPIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 404 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------I 438
             +G P  P    PG  GYPG PG  G KG KG+                         I
Sbjct: 304 GENGQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 439 GEPGRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR---------- 486
           G PG  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG            
Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 487 -GLDGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI-------- 527
            GLDG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+        
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTC 481

Query: 528 -----PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG-- 580
                 G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG  
Sbjct: 482 FNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 581 -----------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629
                        G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601

Query: 630 LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS-- 681
            GP G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +  
Sbjct: 602 RGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 682 --GEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 739
             G+ G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+    
Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK---- 715

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG------ 793
                G PG+ GPPG   T   I                  L+ P  G  G PG      
Sbjct: 716 -----GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPG 752

Query: 794 --RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG- 847
              PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G 
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 848 -----------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPG 887
                       GP G+PG IG P         GDPGP      G  GERG PG+ G PG
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 888 VPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
             GPPG PGLPG    +      G+      P P
Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  501 bits (1290), Expect = e-141
 Identities = 315/719 (43%), Positives = 371/719 (51%), Gaps = 83/719 (11%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG-- 326
            GPPG+ G PG PGPPG  G  G  G++G  G  GP G  G PG PGAPG PG+ G  G  
Sbjct: 491  GPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDI 550

Query: 327  --LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPG------------PPGTAGL 371
                G  G  G +GS G  G PG+PG+ G  G  G+PGP G            PPG  GL
Sbjct: 551  LTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGL 610

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA--------CPPGRSGYP 423
            PG  G +GP+G PG  GPPGP G  G +G  G + G P  P            PG+ G P
Sbjct: 611  PGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAG-NPGQPGIPGPKGDPGQTITQPGKPGLP 668

Query: 424  GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG--EVGAQGPPGAQGLRGITGIVGDKG 481
            G PG  G  G  G+ G PG+ G  G  G +GE G   +G  GPPG +G  GI G  G  G
Sbjct: 669  GNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPG 728

Query: 482  EKGARGLDGEPGPQGLPGAPGDQGQR--GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 539
              G  GL+G PGP G PG  G+ G    GPPG  G  G +GA G +G  G PGP G  G 
Sbjct: 729  TPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGR 788

Query: 540  PGVDGRDGIPGMPGTKGEPGKPGPPG--DAGLQGLPGVPGIPGA------KGVAGEKGST 591
             G+DG  G  G  G  G+PG  GPPG    G+QG PG PGIPG        G+ GEKG  
Sbjct: 789  TGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDP 848

Query: 592  GAPGK--PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            G PG   PG  G  G PG  G PG +GP G  GLPG  G  G  G+ G  G +G  G PG
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPG 908

Query: 650  LPGLPGPPGLPGMKGDRGVVGEPG---PKGEQGASGEEGEAGERGELGD--IGLPGPKGS 704
              G+PG  G+PG+KGD G+ G+PG   P GE+G+ GE G  G  G +    +G  G KG 
Sbjct: 909  PLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGE 968

Query: 705  AGNPGEPGLRGPEGSRGLPG------VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPT 758
             G PG PG+ GP+G +GLPG      + G  G PGP G +G  G  G PG+ GPPG   T
Sbjct: 969  PGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGT 1028

Query: 759  DQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGL 818
                       I +        ++ P  G +G+PG+PG PG PG  G+ G PG   I GL
Sbjct: 1029 -----------IGDMGFPGPQGVEGPP-GPSGVPGQPGSPGLPGQKGDKGDPGISSI-GL 1075

Query: 819  PGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGE 876
            PG+ GP G  GL G  G+ G KG  G PG  G  G PGA G PG PG P + G  G  G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 877  RGPPGVAGIPGVPGP---------PGP------PGLPGFCEPASCTMQAGQRAF-NKGP 919
             GPPG  G+PG PGP         PGP      PG  G   PA    + GQ  F N GP
Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 313
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 314 ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 366
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 404
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 405 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 448
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 449 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 494
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 495 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 550
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 551 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 601
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 602 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 641
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 642 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 698
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 699 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 756
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 806
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 807 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 864
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 865 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 915
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 916 NKGPDP 921
              P P
Sbjct: 949 PGPPGP 954



 Score =  477 bits (1228), Expect = e-134
 Identities = 289/644 (44%), Positives = 331/644 (51%), Gaps = 102/644 (15%)

Query: 266  DERGPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEP 310
            D  GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G P
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP 913

Query: 311  GKPGAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPG 350
            G+ G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG 973

Query: 351  SRGFPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD 406
              G  G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG   
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 407  GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ--GHKGEEGDQGELGEVGAQGP 464
                     PPG SG PG PG  G  G KG+ G+PG    G  G  G +GE G  G  G 
Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093

Query: 465  PGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGA 524
            PG +G  G  G+ G  G  GA+G  G PG  G PG PG +G  GPPG  G  G+ G  G 
Sbjct: 1094 PGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGG 1153

Query: 525  RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK-----PGPP---------GDAGLQ 570
             G PG PGP G+ G P   G+DGIPG  G KGEPG+     PGPP         GD GL 
Sbjct: 1154 GGHPGQPGPPGEKGKP---GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLP 1210

Query: 571  GLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL 630
            G+PG PG+PG KG  G  G  G  G PG  G+ G P  +GP G  GP+GP G PG +G  
Sbjct: 1211 GIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLP 1269

Query: 631  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 690
            GP G PGLPG  G  G  G PG PG PGLPG+KGD+G  G  G  G  G +G +G+ G  
Sbjct: 1270 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1329

Query: 691  GELGDIGLPGPK---GSAGNPGEPGLRGPEGSRGLPGVEGP----RGPPGPRGVQGEQGA 743
            G  G  G+ GP    GSAG  GEPGL GP G  GLPG  G     +G  GP G+ G+ G 
Sbjct: 1330 GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGL 1389

Query: 744  TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP 803
             GLPG QGP                                     GLPG  GPPG PG 
Sbjct: 1390 KGLPGPQGP------------------------------------QGLPGPTGPPGDPGR 1413

Query: 804  PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 847
             G  GF G  G +G PG+ G PG  GL GP G  G +G  GPPG
Sbjct: 1414 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  457 bits (1177), Expect = e-128
 Identities = 276/634 (43%), Positives = 322/634 (50%), Gaps = 118/634 (18%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 317
            ERG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 318  ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 356
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 357  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 405
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 451
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 511
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 512  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 569
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 570  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG------PRGPQGL 623
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  G      P GP GL
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGL 1277

Query: 624  PGS------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG---- 673
            PG+      +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG    
Sbjct: 1278 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1337

Query: 674  --PKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPGVEG 727
              P G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG +G
Sbjct: 1338 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1397

Query: 728  PRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 787
            P+G PGP G  G+ G  GLPG  G  GR                               G
Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPGFDGAGGR------------------------------KG 1427

Query: 788  ATGLPGRP------GPPGPPGPPGENGFPGQMGI 815
              GLPG+P      GPPGP G  G  G PG   +
Sbjct: 1428 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  380 bits (977), Expect = e-105
 Identities = 247/584 (42%), Positives = 288/584 (49%), Gaps = 105/584 (17%)

Query: 417 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI 476
           PG  G+PGLPG  G +G  G  G+ G  G  G  G +G  G  G  G PG  GL G+ G 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH 112

Query: 477 VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 536
            G  G +G  G +G  G +G PG+PG  G +GPPG  G  G +G  G+  +  LPGPKG+
Sbjct: 113 DGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172

Query: 537 TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP-----------GAKGVA 585
              PG  G  GI G+PG  G PG  GPPG  GL G PG PG+P           G KG  
Sbjct: 173 ---PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229

Query: 586 GEKGSTGAPGKPGQM-------------GNSGKPGQQGPPGEVGPRGPQGLP----GSRG 628
           GE+G  G PG PGQ+             G+ G PG +GPPG  G RGP G P    G +G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP------GMKGDRGVVGEPGPK------- 675
           E G  G  G PGK G  G PG+PGLPG PG P      G KG +G  G PGP        
Sbjct: 290 EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRP 349

Query: 676 ------GEQGASGEEGEAGERGELGDIGLPGPKGSAGNP-----GEPGLRGPEGSRGLPG 724
                 GE+G  G  G  GE+GE G  G+ GP G  G P     G PG  G  G RG  G
Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG 409

Query: 725 VEGPRG--PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM------------RVI 770
            EGP G   PGP G+ G+ GA GLPG  GP G  P      ++C             + +
Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGPPGPPGSPGDKGL 467

Query: 771 QEHFAEMAASLKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQ---------MG 814
           Q    E      + D       +G +G PG+PG PG PGPPG  GFPGQ          G
Sbjct: 468 Q---GEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG 524

Query: 815 IRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR----GPNGLPGAIGLP 860
            +GLPGI G PGA G  G KG+           G+KGE G PG     G  G PG  GLP
Sbjct: 525 PKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584

Query: 861 GDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 903
           G PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  348 bits (892), Expect = 2e-95
 Identities = 224/551 (40%), Positives = 262/551 (47%), Gaps = 123/551 (22%)

Query: 474 TGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP 533
           +GI G+KGE+G  GL+G PG  G PG  G  G RG  G+ G  G  G +G RG PGLPG 
Sbjct: 41  SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100

Query: 534 KGDTGLPGVDGRDG------IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587
            G  GLPG+ G DG      IPG  GTKGE G PG PG  GLQG PG PGIPG KG  G 
Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 588 KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL-- 645
              +  PG  G  G  G PG QG PG  G  GP G PG  G +GP G PGLPG  G++  
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 646 ---------GSPGLPGLPGPPGL----------------PGMKGDRGVVGEPG------- 673
                    G  GL G PGPPG                  G+ GDRG  G PG       
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 674 PKGEQGASGEEGEAGERGEL---GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 730
           P GE+G  GE+GE G+RG+    G+ G PG  G  G+PG PG  G +G +G  G  GP G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 731 PPG---PR----------------GVQGEQGATGLPGVQGPPG-RAPTDQHIKQ------ 764
           PPG   PR                G+ GE+G  G PG+QGPPG   P    +        
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 765 -VCMRVIQEHFAEMAASLKRP-----DSGATGLPG----------------RPGPPGPPG 802
               R  +        S+  P       GA GLPG                 PGPPGPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 803 PPGENGFPGQMGIR----------------------GLPGIKGPPGALGLRGPKGDLGEK 840
            PG+ G  G+ G++                      GLPG+ GPPG+LG  G KG+ G+ 
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 841 GERGPPGRGPNGLPGAIGLPGDPGPASY--------GRNGRDGERGPPGVAGIPGVPGPP 892
           G  GP  +G  G+PGA G PG PG            G  G  GE G PG  G+PG+PG P
Sbjct: 521 GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 893 GPPGLPGFCEP 903
           G  GLPG   P
Sbjct: 579 GQDGLPGLPGP 589



 Score =  297 bits (761), Expect = 3e-80
 Identities = 191/453 (42%), Positives = 225/453 (49%), Gaps = 80/453 (17%)

Query: 508 GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 567
           G  GE G +G  G EG  G+PG PGP+G  G  G  G DGIPG PG KG  G PG     
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG----- 96

Query: 568 GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK---PGQQGPPGEVGPRGPQGLP 624
               LPG PG PG  G+ G  G+ G  G PG  G  G+   PG  G PG  GP GP G+P
Sbjct: 97  ----LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 625 GSRGE---------LGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPGMKGDRGVVGEP 672
           G +GE          GP G+PG PG  G  G PG  G+P   GPPG PG+ G  G  G P
Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 673 GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG----------NPGEPGLRGPEGSRGL 722
           GPKG  G +  +G  GE+GE G  G PGP G               G+ GL G  G  G 
Sbjct: 213 GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 723 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
           PG+ GP GPPG  G +GE+G  G PG +G PG                           K
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPG---------------------------K 302

Query: 783 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG----PPGALGLRGPKGDL- 837
             ++G  G+PG PG PG PG PG +G  GQ G  G PG  G     PG     G KG++ 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 838 -----GEKGERGPPG-RGPNGLPGAIG--LPGDPGPASY-GRNGRDGERGPPGVA--GIP 886
                GEKGERG PG +GP GLPG  G  + G PGP  + G  G+ G+ GPPG++  G P
Sbjct: 363 LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 887 GVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G+ G PG PGLPG   PA   +         GP
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score =  283 bits (725), Expect = 4e-76
 Identities = 163/349 (46%), Positives = 186/349 (53%), Gaps = 37/349 (10%)

Query: 264  TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
            T   +G PG  G PG PGPPG  GI G  G+ G  G PGP G  G PG+PG PG+ G PG
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPG 1170

Query: 324  ADGLTGPDGS--------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 369
             DG+ GP G               PG  G  GQKG+ G+PG  G PG  +PGP G PG  
Sbjct: 1171 QDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG--LPGPKGEPGFH 1228

Query: 370  GLPGELGRVGPVGDPGR--RGPPGPPGPPGPRGTIGFH-----DGDPLCP-NACPPGRSG 421
            G PG  G  GP G PG    GP G PGP GP G  GF      +G P  P N    G  G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKG 1288

Query: 422  YPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKG 481
             PG PG+ G  G KG+ G PG QG+ G  G  G  G+ G  G PG  G++G +G+ G  G
Sbjct: 1289 NPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAG 1348

Query: 482  EKGARGLDGEPGPQGLPGAPG-------DQGQRGPPGEAGPKGDRGAEGARGIPGLPGPK 534
             +G  GL G PGP GLPG  G       D G  G PG+ G KG  G +G +G+PG  GP 
Sbjct: 1349 PEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPP 1408

Query: 535  GD---TGLPGVD---GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
            GD    GLPG D   GR G PG+PG  G  G  GPPG  GLQG PG PG
Sbjct: 1409 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  207 bits (527), Expect = 4e-53
 Identities = 132/325 (40%), Positives = 154/325 (47%), Gaps = 79/325 (24%)

Query: 624 PGSR----GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 679
           PGS+    G  G  G  G PG  G  G PG PG  GPPG  G KGD G+ G PGPKG +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 680 ASGEEGEAGERG---ELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736
             G  G  G  G     G  G PGP+G  G  G  G RG  GS G PG++GP GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 737 VQGEQGA---TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793
           ++GE G+   + LPG +G PG                                G  G+ G
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGY------------------------------PGPPGIQG 183

Query: 794 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL--RGPKGDLGEKGERGPPG---- 847
            PGP G PGP G  G PG MG  G PG+ GP G +GL  +GPKG+ GE+G +GPPG    
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 848 ----------------------RGPNGLPGAIGLPGDPG-----------PASYGRNGRD 874
                                 RGP G PG  G PG PG           P   G+ G+D
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 875 GERGPPGVAGIPGVPGPPGPPGLPG 899
           GE G PG+ G+PG PG PG PG  G
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDG 328



 Score =  187 bits (475), Expect = 4e-47
 Identities = 111/250 (44%), Positives = 125/250 (50%), Gaps = 37/250 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            PA   P      +GPPG  G  G PGP G PG+ G  G +G K         G PG+PG 
Sbjct: 1245 PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEK---------GNPGQPGL 1295

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375
            PG PG  G  G  G  G+PG  G  G KG+PG+PG  GFP  G+ GP G PG+A      
Sbjct: 1296 PGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP--GMKGPSGVPGSA------ 1347

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
               GP G+PG  GPPGPPG PGP G      GD     A PPG  G PGL G+       
Sbjct: 1348 ---GPEGEPGLIGPPGPPGLPGPSGQSIIIKGD-----AGPPGIPGQPGLKGL------- 1392

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
                 PG QG +G  G  G  G+ G  G PG  G  G  G  G  G+ G RGLDG PGP 
Sbjct: 1393 -----PGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD 1447

Query: 496  GLPGAPGDQG 505
            GL G PG  G
Sbjct: 1448 GLQGPPGPPG 1457



 Score =  156 bits (394), Expect = 1e-37
 Identities = 94/210 (44%), Positives = 102/210 (48%), Gaps = 17/210 (8%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 306
            P R     LP    P       G  GE+G PG PG PG+P   G+ GD+GP G  G PG 
Sbjct: 1260 PGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP---GLKGDQGPPGLQGNPGR 1316

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG-----IPG 361
             G  G  G PG PG PG  G+ GP G PGS G +G+ G  G PG  G PG       I G
Sbjct: 1317 PGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKG 1376

Query: 362  PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSG 421
              GPPG  G PG  G  GP G  G  GP GPPG PG  G  GF DG          GR G
Sbjct: 1377 DAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF-DG--------AGGRKG 1427

Query: 422  YPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 451
             PGLPG  G +G  G  G  G QG  G  G
Sbjct: 1428 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  558 bits (1439), Expect = e-159
 Identities = 342/773 (44%), Positives = 398/773 (51%), Gaps = 155/773 (20%)

Query: 261  PSQTTDERGPPG---------EQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGP 306
            P QT  + G PG         + G PG PG PG PG+ GI G +G  G PG     PPGP
Sbjct: 655  PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGP 714

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG-------- 356
             G PG PG PG PGTPG  GL GP G PG  G KG+ G   PG PG  G PG        
Sbjct: 715  KGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPK 774

Query: 357  --RGIPGPPGPPGTAGL---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRG 400
              RG PGPPGPPG  GL   PG  G VGP G PG            +GPPGPPG PGP G
Sbjct: 775  GDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG 834

Query: 401  TIGFHD-----GDPLCPNAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGD 452
              G H      GDP  P      PPG  G PG+PG  G  G  G  G PG+ G  G  G 
Sbjct: 835  QPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGT 894

Query: 453  QGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGE 512
            +GE+G +G  GPPG  G+ G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG 
Sbjct: 895  KGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGP 954

Query: 513  AGP-----KGDRGAEGARGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKP 561
              P     KG++G  G  GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG P
Sbjct: 955  MDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLP 1014

Query: 562  GPPG------------DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG----- 604
            G PG            D G  G  GV G PG  GV G+ GS G PG+ G  G+ G     
Sbjct: 1015 GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIG 1074

Query: 605  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG  GP GE G  G  G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG
Sbjct: 1075 LPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKG 1134

Query: 665  ------DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG------ 712
                  + G+ GEPGP G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG      
Sbjct: 1135 ISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194

Query: 713  -----LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM 767
                 L G +G  GLPG+ G  G PGP+G   E G  G PGVQGPPG   +         
Sbjct: 1195 PGLPGLSGQKGDGGLPGIPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP-------- 1243

Query: 768  RVIQEHFAEMAASLKRP--DSGATGLPGRPGP------PGPPGPPG---------ENGFP 810
                        +L+ P  + G  G PGRPGP      PGP GPPG         E G P
Sbjct: 1244 ----------GPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNP 1293

Query: 811  GQMGIRGLPGIKGP---------PGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLP 860
            GQ G+ GLPG+KG          PG  GL G KGD G  G  G PG +GP+G+PG+ G  
Sbjct: 1294 GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 861  GDPG-------PASYGRNGRD----GERGPPGVAGIP---GVPGPPGPPGLPG 899
            G+PG       P   G +G+     G+ GPPG+ G P   G+PGP GP GLPG
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406



 Score =  546 bits (1407), Expect = e-155
 Identities = 327/704 (46%), Positives = 372/704 (52%), Gaps = 91/704 (12%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            GP G++G PGPPGPPG  G+DG+ G +G  GP G PGP G PG PG  G  G PG  G+ 
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIP 830

Query: 329  GPDGSPGSIGSKGQKGEPGVPG--------SRGFPG-RGIPGPPGPPGTAGLPGELGRVG 379
            GP G PG  G  G+KG+PG PG         RG PG  G PGP GPPG+ GLPG+ G  G
Sbjct: 831  GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G  G  G  GPPGPPGP G  G   G P        G  G PGLPG  G KG+KGE G
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG--DDGLQGQPGLPGPTGEKGSKGEPG 947

Query: 440  EPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG---LDGEPGP 494
             PG  G       G +GE GE G  G PG  G +G  G+ GD G+ G  G   L G PGP
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGP 1007

Query: 495  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI---------------PGLPGPKGDTGL 539
            +G PG PG  G  GPPG  G  GD G  G +G+               PGLPG KGD G 
Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067

Query: 540  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------LPGVPGIPGAKGVAGEKGSTGA 593
            PG+    G+PG+PG KGEPG PG PG+ G++G      LPG+PG PGAKG  G  G  G 
Sbjct: 1068 PGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126

Query: 594  PGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL 650
            PG PG  G SG PG  G PGE GP    G  G PG  GE G  G  G+PG  G  G PG 
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186

Query: 651  PGL--PGPPGLPGMKGDRGV---------VGEPGPKGEQGASGEEGEAGERGELGDIG-- 697
            PG   PGPPGLPG+ G +G           G PGPKGE G  G  G  G  G  G  G  
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 698  LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 757
            L GPKG+ G  G PG  GP G +GLPG EGP G PG  G++GE+G  G PG+ G PG   
Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306

Query: 758  TDQHIKQVCMRVIQEHFAEMAASLKRPD-SGATGLPGRPGPPGPPGPPGENGFPGQMGIR 816
                          +    +  +  RP  +G  G PG PG PG PG  G +G PG  G  
Sbjct: 1307 -------------DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 817  GLPGIKGPPGALGLRGPKGD-LGEKGERGPPG-------------RGPNGLPGAIGLPGD 862
            G PG+ GPPG  GL GP G  +  KG+ GPPG             +GP GLPG  G PGD
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 863  PG----PASYGRNGRDGERGPPGVAGIPGVPGPPGP---PGLPG 899
            PG    P   G  GR G+ G PG  G  G+ GPPGP    G PG
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1457



 Score =  543 bits (1398), Expect = e-154
 Identities = 332/726 (45%), Positives = 376/726 (51%), Gaps = 91/726 (12%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPK---GPPGP 303
            P+ E    LP    P      +G  G +G  G PGPPG PG  G+DG  GPK   GP G 
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQ 806

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGE--------PGVPGSRGFP 355
            PGP G PG PG  G  G PG  G+ GP G PG  G  G+KG+        PG PG RG P
Sbjct: 807  PGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSP 865

Query: 356  G-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA 414
            G  G PGP GPPG+ GLPG+ G  G  G  G  G  GPPGPPGP G  G   G P     
Sbjct: 866  GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG- 923

Query: 415  CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRG 472
               G  G PGLPG  G KG+KGE G PG  G       G +GE GE G  G PG  G +G
Sbjct: 924  -DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKG 982

Query: 473  ITGIVGDKGE---KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI-- 527
              G+ GD G+    G  GL G PGP+G PG PG  G  GPPG  G  GD G  G +G+  
Sbjct: 983  YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEG 1042

Query: 528  -------------PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQ---- 570
                         PGLPG KGD G PG+    G+PG+PG KGEPG PG PG+ G++    
Sbjct: 1043 PPGPSGVPGQPGSPGLPGQKGDKGDPGISS-IGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101

Query: 571  --GLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPG 625
              GLPG+PG PGAKG  G  G  G PG PG  G SG PG  G PGE GP    G  G PG
Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161

Query: 626  SRGELGPVGSPGLPGKLGSLGSPGLPGL--PGPPGLPGMKGDR---------GVVGEPGP 674
              GE G  G  G+PG  G  G PG PG   PGPPGLPG+ G +         G  G PGP
Sbjct: 1162 PPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGP 1221

Query: 675  KGEQGASGEEGEAGERGELGDIG--LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPP 732
            KGE G  G  G  G  G  G  G  L GPKG+ G  G PG  GP G +GLPG EGP G P
Sbjct: 1222 KGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLP 1281

Query: 733  GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD-SGATGL 791
            G  G++GE+G  G PG+ G PG                 +    +  +  RP  +G  G 
Sbjct: 1282 GNGGIKGEKGNPGQPGLPGLPGLKG-------------DQGPPGLQGNPGRPGLNGMKGD 1328

Query: 792  PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG-DLGEKGERGPPG--- 847
            PG PG PG PG  G +G PG  G  G PG+ GPPG  GL GP G  +  KG+ GPPG   
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1388

Query: 848  ----------RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPG 893
                      +GP GLPG  G PGDPG    P   G  GR G+ G PG  G  G+ GPPG
Sbjct: 1389 QPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPG 1448

Query: 894  PPGLPG 899
            P GL G
Sbjct: 1449 PDGLQG 1454



 Score =  533 bits (1374), Expect = e-151
 Identities = 319/711 (44%), Positives = 361/711 (50%), Gaps = 89/711 (12%)

Query: 267  ERGPPGEQGPPGPPG-----------PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK--- 312
            ERGPPG  G PG PG           PPG  G  GI G  G  G PG PGP G+PG+   
Sbjct: 601  ERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 313  -PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 371
             PG PG PG PG DG  G  G PG  G  G  G PG  G  G PG G+PGPPGP G  G+
Sbjct: 661  QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGI 720

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGH 431
            PG  G  G  G  G  GPPGPPG PGP+G  GF       P   PPG  G PG  G  G 
Sbjct: 721  PGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGP 773

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE 491
            KG +G  G PG  G  G +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G 
Sbjct: 774  KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGP 832

Query: 492  PGPQGLPGAPGDQGQRGPPG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 549
             G  GL G PG++G  GPPG    GP G+RG+ G   IPG PGP G  G PG+ G+ G  
Sbjct: 833  IGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG---IPGAPGPIGPPGSPGLPGKAGAS 889

Query: 550  GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 609
            G PGTKGE G  GPPG  G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 610  GPPGEV-----------------------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLG 646
            GPPG +                       GP+G QGLPG  G+ G  G PGLPG  G  G
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009

Query: 647  SPGLPGLPG---PPGLPGMKGD------RGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
            +PGLPG PG   PPGL G  GD      +GV G PGP G  G  G  G  G++G+ GD G
Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069

Query: 698  --------LPGPKG---------------SAGNPGEPGLRGPEGSRG---LPGVEGPRGP 731
                    LPGPKG               S G+PG PGL G  G++G   LPG  G  GP
Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129

Query: 732  PGPRGVQGEQGATGLPGVQGPPGRA--PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGAT 789
            PGP+G+ G  G  GLPG  GP G    P          +  Q+     A     P     
Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGF 1189

Query: 790  GLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRG 849
            G PG PG PG  G  G+ G PG  G  GLPG KG PG  G  G +G  G  G  GP   G
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249

Query: 850  PNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            P G PG  G PG PGP  + G  G +G  G PG  GI G  G PG PGLPG
Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPG 1300



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 329 GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 382
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 383 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 434
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 435 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 478
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 479 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 530 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 579
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 580 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 627
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 628 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 671
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 672 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 721
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 722 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 768
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 769 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 825 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 882
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 883 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  516 bits (1329), Expect = e-146
 Identities = 332/784 (42%), Positives = 377/784 (48%), Gaps = 155/784 (19%)

Query: 267  ERGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPPGPPG-----PAGEPGKPGAP 316
            ERG PG QGPPG PGPPG      PG  G  G+RG KG  GPPG     P G  G+PGAP
Sbjct: 372  ERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAP 431

Query: 317  GKPGTPGADGL----------TGPDGSPGSIGSKGQKGEPGVPGSRGF------------ 354
            G PG PG  G            GP G PGS G KG +GE GV G +G             
Sbjct: 432  GLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISG 491

Query: 355  -PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGRRGPPGPPGPPGPRGTIGF-- 404
             PG+ G+PG PGPPG+ G PG+ G        GP G PG  G PG PG PG +G  G   
Sbjct: 492  PPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDIL 551

Query: 405  ----------HDGDPLCPNAC----PPGRSGYPGLPGMRGHKGA---KGEIGEPGRQGHK 447
                        G P  P        PG+ G PGLPG +G  G    KGE G PG  G  
Sbjct: 552  TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLP 611

Query: 448  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ------------ 495
            G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G  G+PG              
Sbjct: 612  GLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN 670

Query: 496  -------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548
                   GLPG PG  GQ G PG  G KG+ G  G  G+PG PGPKG  G+PG  G  G 
Sbjct: 671  PGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPGIPGPPGAPGT 729

Query: 549  PGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 603
            PG  G +G PG PG PG  G     L G PG PG+PG KG  G KG  G PG PG  G +
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 604  GKPGQQGPPGEVGPRGP--------------QGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            G  G  GP G+VGP G               QG PG  G  GP+G PGL G  G  G PG
Sbjct: 790  GLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPG 849

Query: 650  LPGL--PGP------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
             PGL  PGP      PG+PG  G  G  G PG  G+ GASG  G  GE G +G  G PGP
Sbjct: 850  PPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGP 909

Query: 702  KGSAGNPGEPGLRGPEGSRGLPGVEGPR------------GPPGP--------RGVQGEQ 741
             G  G  G PGL+G +G +G PG+ GP             GPPGP        +G +GE 
Sbjct: 910  LGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEP 969

Query: 742  GATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP 801
            G  G+PGV GP G                              D G  GL G+PG PGPP
Sbjct: 970  GLPGIPGVSGPKGYQGLP------------------------GDPGQPGLSGQPGLPGPP 1005

Query: 802  GPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLP 860
            GP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G  G PG+ G  GLPG  G  
Sbjct: 1006 GPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDK 1065

Query: 861  GDPGPASYGRNGRDGERGPPGVAGIPGVP---GPPGPPGLPGFCEPASCTMQAGQRAFNK 917
            GDPG +S G  G  G +G PG+ G PG P   G  G PGLPG         Q G   F  
Sbjct: 1066 GDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPG 1125

Query: 918  GPDP 921
             P P
Sbjct: 1126 TPGP 1129



 Score =  511 bits (1315), Expect = e-144
 Identities = 306/688 (44%), Positives = 360/688 (52%), Gaps = 87/688 (12%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G  G  G PG PG PG PG DG+ G  GPKG PG     GE G PG PG PG PG  G
Sbjct: 559  DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 327  LTGPDG--SPGSIGSKG------QKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 378
              GP G   PG +G KG        G+PG+PG +G PG+ I   PG PG  G PG  G V
Sbjct: 619  PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT-QPGKPGLPGNPGRDGDV 677

Query: 379  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 438
            G  GDPG  G PG PG PG +G  G     P      PPG  G+PG+PG  G  G  G I
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPGRI 733

Query: 439  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 498
            G  G  G  G  G +GE G     GPPG  GL G  G +G KG++G  G  G PG  GL 
Sbjct: 734  GLEGPPGPPGFPGPKGEPG-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD 792

Query: 499  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G PG +G  GP G+ GP G  G  G     G+ GP G  G+PG  G+ G+ G+PG KG+P
Sbjct: 793  GLPGPKGDVGPNGQPGPMGPPGLPGI----GVQGPPGPPGIPGPIGQPGLHGIPGEKGDP 848

Query: 559  GKPG-----PPGDAGLQGLPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 610
            G PG     PPG+ G  G+PG PG    PG+ G+ G+ G++G PG  G+MG  G PG   
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG--- 905

Query: 611  PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-----LPGMKGD 665
            PPG +G  G  G+PG +G+ G  G PGLPG  G  GS G PGLPGPPG     L G KG+
Sbjct: 906  PPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGE 965

Query: 666  RGVVGEPG------PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 719
            +G  G PG      PKG QG  G+ G+ G  G+ G  G PGPKG+ G PG+PGL GP G 
Sbjct: 966  KGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGL 1025

Query: 720  RG------LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEH 773
            +G       PG +G  GPPGP GV G+ G+ GLPG +G  G                   
Sbjct: 1026 KGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD------------------ 1067

Query: 774  FAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 833
                      P   + GLPG PGP G PG PG  G PG  G  G PG+ G PG  G +G 
Sbjct: 1068 ----------PGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 834  KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP 892
             G  G  G  GPPG +G +G PG  GLPG+PGP   G           G  G PG PG  
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG-----------GHPGQPGPPGEK 1166

Query: 893  GPPGLPGFCEPASCTMQAGQRAF-NKGP 919
            G PG  G   PA    + GQ  F N GP
Sbjct: 1167 GKPGQDGIPGPAGQKGEPGQPGFGNPGP 1194



 Score =  508 bits (1308), Expect = e-143
 Identities = 330/814 (40%), Positives = 379/814 (46%), Gaps = 190/814 (23%)

Query: 264 TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
           T  ERG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG
Sbjct: 127 TKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPG 186

Query: 324 ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP----- 366
             G+ GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP     
Sbjct: 187 PTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE 246

Query: 367 -----------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG-- 403
                      G  GLPG+    GP G PG RGPPGPP          G PG RG  G  
Sbjct: 247 QKRPIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 404 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------I 438
             +G P  P    PG  GYPG PG  G KG KG+                         I
Sbjct: 304 GENGQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNI 361

Query: 439 GEPGRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR---------- 486
           G PG  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG            
Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421

Query: 487 -GLDGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI-------- 527
            GLDG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+        
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTC 481

Query: 528 -----PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG-- 580
                 G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG  
Sbjct: 482 FNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 581 -----------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629
                        G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE
Sbjct: 542 GSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGE 601

Query: 630 LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS-- 681
            GP G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +  
Sbjct: 602 RGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTIT 660

Query: 682 --GEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 739
             G+ G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+    
Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK---- 715

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG------ 793
                G PG+ GPPG   T   I                  L+ P  G  G PG      
Sbjct: 716 -----GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPG 752

Query: 794 --RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG- 847
              PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G 
Sbjct: 753 FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGP 812

Query: 848 -----------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPG 887
                       GP G+PG IG P         GDPGP      G  GERG PG+ G PG
Sbjct: 813 PGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872

Query: 888 VPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
             GPPG PGLPG    +      G+      P P
Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 313
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 314 ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 366
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 404
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 405 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 448
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 449 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 494
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 495 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 550
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 551 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 601
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 602 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 641
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 642 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 698
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 699 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 756
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 806
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 807 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 864
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 865 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 915
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 916 NKGPDP 921
              P P
Sbjct: 949 PGPPGP 954



 Score =  468 bits (1203), Expect = e-131
 Identities = 287/652 (44%), Positives = 332/652 (50%), Gaps = 115/652 (17%)

Query: 266  DERGPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEP 310
            D  GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G P
Sbjct: 854  DVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP 913

Query: 311  GKPGAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPG 350
            G+ G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG
Sbjct: 914  GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPG 973

Query: 351  SRGFPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH- 405
              G  G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG   
Sbjct: 974  IPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMG 1033

Query: 406  -------DGDPLCPNACPPGRSGYPGLPGMRGHK--------------GAKGEIGEPGRQ 444
                   +G P  P+   PG+ G PGLPG +G K              G KGE G PG  
Sbjct: 1034 FPGPQGVEGPP-GPSGV-PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091

Query: 445  GHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ 504
            G+ G +G  G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 505  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV--DGRDGIPGMPGTKGEPGKPG 562
            G  G PG+ GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 563  PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG 622
             PG+ GL G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  GP G QG
Sbjct: 1212 IPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQG 1270

Query: 623  LPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASG 682
            LP      GP G PGLPG  G  G  G PG PG PGLPG+KGD+G  G  G  G  G +G
Sbjct: 1271 LP------GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNG 1324

Query: 683  EEGEAGERGELGDIGLPGPK---GSAGNPGEPGLRGPEGSRGLPGVEGP----RGPPGPR 735
             +G+ G  G  G  G+ GP    GSAG  GEPGL GP G  GLPG  G     +G  GP 
Sbjct: 1325 MKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPP 1384

Query: 736  GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP 795
            G+ G+ G  GLPG QGP G                                G TG     
Sbjct: 1385 GIPGQPGLKGLPGPQGPQGL------------------------------PGPTG----- 1409

Query: 796  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 847
             PPG PG  G  GF G  G +G PG+ G PG  GL GP G  G +G  GPPG
Sbjct: 1410 -PPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  458 bits (1178), Expect = e-128
 Identities = 276/637 (43%), Positives = 321/637 (50%), Gaps = 121/637 (18%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 317
            ERG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 318  ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 356
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 357  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 405
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 451
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 511
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 512  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 569
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 570  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG---- 625
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  GP G QGLPG    
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGP 1277

Query: 626  -----------SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG- 673
                        +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG 
Sbjct: 1278 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1337

Query: 674  -----PKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPG 724
                 P G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG
Sbjct: 1338 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397

Query: 725  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
             +GP+G PGP G  G+ G  GLPG  G  GR                             
Sbjct: 1398 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR----------------------------- 1428

Query: 785  DSGATGLPGRP------GPPGPPGPPGENGFPGQMGI 815
              G  GLPG+P      GPPGP G  G  G PG   +
Sbjct: 1429 -KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1464



 Score =  380 bits (977), Expect = e-105
 Identities = 247/584 (42%), Positives = 288/584 (49%), Gaps = 105/584 (17%)

Query: 417 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI 476
           PG  G+PGLPG  G +G  G  G+ G  G  G  G +G  G  G  G PG  GL G+ G 
Sbjct: 53  PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGH 112

Query: 477 VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 536
            G  G +G  G +G  G +G PG+PG  G +GPPG  G  G +G  G+  +  LPGPKG+
Sbjct: 113 DGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN 172

Query: 537 TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP-----------GAKGVA 585
              PG  G  GI G+PG  G PG  GPPG  GL G PG PG+P           G KG  
Sbjct: 173 ---PGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEK 229

Query: 586 GEKGSTGAPGKPGQM-------------GNSGKPGQQGPPGEVGPRGPQGLP----GSRG 628
           GE+G  G PG PGQ+             G+ G PG +GPPG  G RGP G P    G +G
Sbjct: 230 GEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKG 289

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP------GMKGDRGVVGEPGPK------- 675
           E G  G  G PGK G  G PG+PGLPG PG P      G KG +G  G PGP        
Sbjct: 290 EQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRP 349

Query: 676 ------GEQGASGEEGEAGERGELGDIGLPGPKGSAGNP-----GEPGLRGPEGSRGLPG 724
                 GE+G  G  G  GE+GE G  G+ GP G  G P     G PG  G  G RG  G
Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKG 409

Query: 725 VEGPRG--PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCM------------RVI 770
            EGP G   PGP G+ G+ GA GLPG  GP G  P      ++C             + +
Sbjct: 410 DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAG--PHIPPSDEICEPGPPGPPGSPGDKGL 467

Query: 771 QEHFAEMAASLKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQ---------MG 814
           Q    E      + D       +G +G PG+PG PG PGPPG  GFPGQ          G
Sbjct: 468 Q---GEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATG 524

Query: 815 IRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR----GPNGLPGAIGLP 860
            +GLPGI G PGA G  G KG+           G+KGE G PG     G  G PG  GLP
Sbjct: 525 PKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584

Query: 861 GDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 903
           G PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  348 bits (892), Expect = 2e-95
 Identities = 224/551 (40%), Positives = 262/551 (47%), Gaps = 123/551 (22%)

Query: 474 TGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP 533
           +GI G+KGE+G  GL+G PG  G PG  G  G RG  G+ G  G  G +G RG PGLPG 
Sbjct: 41  SGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGF 100

Query: 534 KGDTGLPGVDGRDG------IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587
            G  GLPG+ G DG      IPG  GTKGE G PG PG  GLQG PG PGIPG KG  G 
Sbjct: 101 PGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGS 160

Query: 588 KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL-- 645
              +  PG  G  G  G PG QG PG  G  GP G PG  G +GP G PGLPG  G++  
Sbjct: 161 IIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL 220

Query: 646 ---------GSPGLPGLPGPPGL----------------PGMKGDRGVVGEPG------- 673
                    G  GL G PGPPG                  G+ GDRG  G PG       
Sbjct: 221 NFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGP 280

Query: 674 PKGEQGASGEEGEAGERGEL---GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 730
           P GE+G  GE+GE G+RG+    G+ G PG  G  G+PG PG  G +G +G  G  GP G
Sbjct: 281 PGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPG 340

Query: 731 PPG---PR----------------GVQGEQGATGLPGVQGPPG-RAPTDQHIKQ------ 764
           PPG   PR                G+ GE+G  G PG+QGPPG   P    +        
Sbjct: 341 PPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPG 400

Query: 765 -VCMRVIQEHFAEMAASLKRP-----DSGATGLPG----------------RPGPPGPPG 802
               R  +        S+  P       GA GLPG                 PGPPGPPG
Sbjct: 401 FPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPG 460

Query: 803 PPGENGFPGQMGIR----------------------GLPGIKGPPGALGLRGPKGDLGEK 840
            PG+ G  G+ G++                      GLPG+ GPPG+LG  G KG+ G+ 
Sbjct: 461 SPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQA 520

Query: 841 GERGPPGRGPNGLPGAIGLPGDPGPASY--------GRNGRDGERGPPGVAGIPGVPGPP 892
           G  GP  +G  G+PGA G PG PG            G  G  GE G PG  G+PG+PG P
Sbjct: 521 GATGP--KGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578

Query: 893 GPPGLPGFCEP 903
           G  GLPG   P
Sbjct: 579 GQDGLPGLPGP 589



 Score =  297 bits (761), Expect = 3e-80
 Identities = 191/453 (42%), Positives = 225/453 (49%), Gaps = 80/453 (17%)

Query: 508 GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 567
           G  GE G +G  G EG  G+PG PGP+G  G  G  G DGIPG PG KG  G PG     
Sbjct: 42  GIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPG----- 96

Query: 568 GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK---PGQQGPPGEVGPRGPQGLP 624
               LPG PG PG  G+ G  G+ G  G PG  G  G+   PG  G PG  GP GP G+P
Sbjct: 97  ----LPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIP 152

Query: 625 GSRGE---------LGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPGMKGDRGVVGEP 672
           G +GE          GP G+PG PG  G  G PG  G+P   GPPG PG+ G  G  G P
Sbjct: 153 GMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLP 212

Query: 673 GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG----------NPGEPGLRGPEGSRGL 722
           GPKG  G +  +G  GE+GE G  G PGP G               G+ GL G  G  G 
Sbjct: 213 GPKGNMGLN-FQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP 271

Query: 723 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
           PG+ GP GPPG  G +GE+G  G PG +G PG                           K
Sbjct: 272 PGIRGPPGPPG--GEKGEKGEQGEPGKRGKPG---------------------------K 302

Query: 783 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG----PPGALGLRGPKGDL- 837
             ++G  G+PG PG PG PG PG +G  GQ G  G PG  G     PG     G KG++ 
Sbjct: 303 DGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIG 362

Query: 838 -----GEKGERGPPG-RGPNGLPGAIG--LPGDPGPASY-GRNGRDGERGPPGVA--GIP 886
                GEKGERG PG +GP GLPG  G  + G PGP  + G  G+ G+ GPPG++  G P
Sbjct: 363 LPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPP 422

Query: 887 GVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G+ G PG PGLPG   PA   +         GP
Sbjct: 423 GLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGP 455



 Score =  283 bits (725), Expect = 4e-76
 Identities = 163/352 (46%), Positives = 187/352 (53%), Gaps = 40/352 (11%)

Query: 264  TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
            T   +G PG  G PG PGPPG  GI G  G+ G  G PGP G  G PG+PG PG+ G PG
Sbjct: 1111 TPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPG 1170

Query: 324  ADGLTGPDGS--------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 369
             DG+ GP G               PG  G  GQKG+ G+PG  G PG  +PGP G PG  
Sbjct: 1171 QDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG--LPGPKGEPGFH 1228

Query: 370  GLPGELGRVGPVGDPGR-----RGPPGPPGPPGPRGTIGFH-----DGDPLCP-NACPPG 418
            G PG  G  GP G PG      +G PGP GPPG  G  GF      +G P  P N    G
Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKG 1288

Query: 419  RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVG 478
              G PG PG+ G  G KG+ G PG QG+ G  G  G  G+ G  G PG  G++G +G+ G
Sbjct: 1289 EKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPG 1348

Query: 479  DKGEKGARGLDGEPGPQGLPGAPG-------DQGQRGPPGEAGPKGDRGAEGARGIPGLP 531
              G +G  GL G PGP GLPG  G       D G  G PG+ G KG  G +G +G+PG  
Sbjct: 1349 SAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPT 1408

Query: 532  GPKGD---TGLPGVD---GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
            GP GD    GLPG D   GR G PG+PG  G  G  GPPG  GLQG PG PG
Sbjct: 1409 GPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  207 bits (527), Expect = 4e-53
 Identities = 132/325 (40%), Positives = 154/325 (47%), Gaps = 79/325 (24%)

Query: 624 PGSR----GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 679
           PGS+    G  G  G  G PG  G  G PG PG  GPPG  G KGD G+ G PGPKG +G
Sbjct: 34  PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93

Query: 680 ASGEEGEAGERG---ELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736
             G  G  G  G     G  G PGP+G  G  G  G RG  GS G PG++GP GPPG  G
Sbjct: 94  PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPG 153

Query: 737 VQGEQGA---TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 793
           ++GE G+   + LPG +G PG                                G  G+ G
Sbjct: 154 MKGEPGSIIMSSLPGPKGNPGY------------------------------PGPPGIQG 183

Query: 794 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL--RGPKGDLGEKGERGPPG---- 847
            PGP G PGP G  G PG MG  G PG+ GP G +GL  +GPKG+ GE+G +GPPG    
Sbjct: 184 LPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQ 243

Query: 848 ----------------------RGPNGLPGAIGLPGDPG-----------PASYGRNGRD 874
                                 RGP G PG  G PG PG           P   G+ G+D
Sbjct: 244 ISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKD 303

Query: 875 GERGPPGVAGIPGVPGPPGPPGLPG 899
           GE G PG+ G+PG PG PG PG  G
Sbjct: 304 GENGQPGIPGLPGDPGYPGEPGRDG 328



 Score =  156 bits (395), Expect = 7e-38
 Identities = 95/213 (44%), Positives = 103/213 (48%), Gaps = 17/213 (7%)

Query: 244  PLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP 303
            P RP       LP    P       G  GE+G PG PG PG+P   G+ GD+GP G  G 
Sbjct: 1260 PGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP---GLKGDQGPPGLQGN 1316

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG----- 358
            PG  G  G  G PG PG PG  G+ GP G PGS G +G+ G  G PG  G PG       
Sbjct: 1317 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1376

Query: 359  IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPG 418
            I G  GPPG  G PG  G  GP G  G  GP GPPG PG  G  GF DG          G
Sbjct: 1377 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF-DG--------AGG 1427

Query: 419  RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 451
            R G PGLPG  G +G  G  G  G QG  G  G
Sbjct: 1428 RKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  553 bits (1424), Expect = e-157
 Identities = 316/698 (45%), Positives = 369/698 (52%), Gaps = 51/698 (7%)

Query: 249  RETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP------PG 302
            +E  H  P            G PG  GPPG  G PG+ G  G DG+RG KG       PG
Sbjct: 387  QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 446

Query: 303  PPGPAGEPGKPGAPGKPGT--PGADGLTGPDGSPGSIGSKGQKGEPGV---PGSRGFPGR 357
            P GP G+PG PG PG PG    G  GL G  G PG +G+KG +G PG+   PGSRG PG 
Sbjct: 447  PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI 506

Query: 358  GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD----GD----- 408
            G+ GPPGP G           G  G PG RG PG PGP GP G  G       GD     
Sbjct: 507  GVAGPPGPSGPP---------GDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLA 557

Query: 409  -PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA 467
              +C N CPPG  G PGLPG +G KG  G+ G  G +G KGE G  G  G  G  GP G+
Sbjct: 558  KDVC-NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGS 616

Query: 468  QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGPKGDRGAEGA 524
            QG RG  G VG KG++G  G+ G  GP G PG PG     G  GPPG  G  G  G  G 
Sbjct: 617  QGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGP 676

Query: 525  RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV 584
            +G  GLPG  G+ G  G DG+ G PG PG  GEPG PGP G  G  G  G  G  GA G 
Sbjct: 677  QGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGP 736

Query: 585  AGEKGSTGAPGK---PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 641
             GE G+ G PG+   PG+ G++G  G QGP G  GP G  G PGS GE GP G+PG  G 
Sbjct: 737  RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 796

Query: 642  LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
             G  GSPGLPG  GP G PG  G++GV G+ G  G+ G  G +GE G+ G  GD G PG 
Sbjct: 797  KGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG 856

Query: 702  KGSAGNPGEPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPT 758
            KG  G+PG PG +G     G +GLPG  GP GPPGP          G PG  G  G +P+
Sbjct: 857  KGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGP---------PGQPGFPGLRGESPS 907

Query: 759  DQHIKQVCMRVIQEHFAEMAASL--KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIR 816
             + ++++    + +      A L  + P +      GRPGPPGPPG  G  G  G MG  
Sbjct: 908  METLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP 967

Query: 817  GLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            G PG  G  G  G  GPKG+ G KG+ G PG G  G  G  G+PG PG   Y ++G  G 
Sbjct: 968  GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1027

Query: 877  RGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 914
             GP G  G  G PG PGPPG PG C+P+ C   A   A
Sbjct: 1028 PGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAA 1065



 Score =  500 bits (1288), Expect = e-141
 Identities = 295/687 (42%), Positives = 345/687 (50%), Gaps = 95/687 (13%)

Query: 272 GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPD 331
           GE G  G  G PG PG+ G  G++G  G PG  G AG PG PG PG  G  G  G  G  
Sbjct: 250 GEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGEL 309

Query: 332 GSPGSIGSKGQKGEPGVPGSRGFPGR--------GIPGPPGPPGTAGLPGELGRVGPVGD 383
           G PG  G +G+KGE G  G  G PG          +PG  GP G  G PG  G  G  G 
Sbjct: 310 GLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGR 369

Query: 384 PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 443
           PG  GP GP GPPG +G  G H       N   PG  G PG  G  G  GA G  G PG+
Sbjct: 370 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGK 429

Query: 444 QGHKGEE---GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP------ 494
            G +GE+   G++G  G VG +G PGA GL G  G  G  GE G RG  G PGP      
Sbjct: 430 DGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKGD 488

Query: 495 QGLPGAPGDQGQR--------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--- 543
           +G PG PG  G R        GPPG +GP GD+G+ G+RG+PG PGP+G  G  G+    
Sbjct: 489 RGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLL 548

Query: 544 ------------------GRDGIPGMPGTKGEPGKPGPP---------GDAGLQGLPGVP 576
                             G  G+PG+PG KG+ G PG P         G+AG  GLPG P
Sbjct: 549 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 608

Query: 577 GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP 636
           GI G +G  GE+G+ G  G+ G  G+ G PG  GPPG  GP G  G+ G+ G  G  GSP
Sbjct: 609 GIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSP 668

Query: 637 GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE---RGEL 693
           G  G  G  G  GLPG+PG  G  G  G  G  GEPG  GE G  G EG  G    +G  
Sbjct: 669 GKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT 728

Query: 694 GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 753
           GD G PGP+G +G  G PG  G  G  G  G  GP+GP GPRG  G+ G+ G PG  GP 
Sbjct: 729 GDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPS 788

Query: 754 GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQM 813
           G  P  +  K                     ++G+ GLPG  GP GPPG PGE G PG+ 
Sbjct: 789 G-TPGQKGSK--------------------GENGSPGLPGFLGPRGPPGEPGEKGVPGK- 826

Query: 814 GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASYGRNG 872
                 G+ G PG  G +G +GD G KG++GP        PG  G PGDPG P   G  G
Sbjct: 827 -----EGVPGKPGEPGFKGERGDPGIKGDKGP--------PGGKGQPGDPGIPGHKGHTG 873

Query: 873 RDGERGPPGVAGIPGVPGPPGPPGLPG 899
             G +G PG  G  G PGPPG PG PG
Sbjct: 874 LMGPQGLPGENGPVGPPGPPGQPGFPG 900



 Score =  496 bits (1278), Expect = e-140
 Identities = 305/755 (40%), Positives = 365/755 (48%), Gaps = 141/755 (18%)

Query: 269 GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAPGKPGTPGAD 325
           G PGE+G  G PG PG PG+ G  GD+G KG    PG  G  GE G+ G  G PG PG  
Sbjct: 277 GRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336

Query: 326 GLTGPDGS-PGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPGTAGLPGELGRVGP 380
            L  P    PG  G KG+KG+PG+PG  G  GR    G  GP GPPG  G  G  G  G 
Sbjct: 337 SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA 396

Query: 381 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
            G+PG  G  G PGP GP G++G             PG  G PG  G RG KGA GE G 
Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVG------------APGLRGTPGKDGERGEKGAAGEEGS 444

Query: 441 PGRQGHKGEEGDQGELGEVGA--QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 498
           PG  G +G+ G  G  G  G    G PG +G  G+ G +G KG++GA G+ G PG +G P
Sbjct: 445 PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDP 504

Query: 499 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--------------- 543
           G     G  GPPG +GP GD+G+ G+RG+PG PGP+G  G  G+                
Sbjct: 505 GI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560

Query: 544 ------GRDGIPGMPGTKGEPGKPGPPG---------DAGLQGLPGVPGIPGAKGVAGEK 588
                 G  G+PG+PG KG+ G PG PG         +AG  GLPG PGI G +G  GE+
Sbjct: 561 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620

Query: 589 GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 648
           G+ G  G+ G  G+ G PG  GPPG  GP G  G+ G+ G  G  GSPG  G  G  G  
Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680

Query: 649 GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE---RGELGDIGLPGPKGSA 705
           GLPG+PG  G  G  G  G  GEPG  GE G  G EG  G    +G  GD G PGP+G +
Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740

Query: 706 GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 765
           G  G PG  G  G  G  G  GP+GP GPRG  G+ G+ G PG  GP G  P  +  K  
Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG-TPGQKGSKG- 798

Query: 766 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IK 822
                              ++G+ GLPG  GP GPPG PGE G PG+ G+ G PG    K
Sbjct: 799 -------------------ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 839

Query: 823 GPPGALGLRGPKGDLGEKGERGPPG----------RGPNGLPGA---IGLPGDPG----- 864
           G  G  G++G KG  G KG+ G PG           GP GLPG    +G PG PG     
Sbjct: 840 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899

Query: 865 -----------------------------------PASYGRN--GRDGERGPPGVAGIPG 887
                                              P +Y ++  GR G  GPPG  G+PG
Sbjct: 900 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 959

Query: 888 VPGP---PGPPGLPGFCEPASCTMQAGQRAFNKGP 919
             GP   PG PG  G   P+      G+R     P
Sbjct: 960 RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDP 994



 Score =  437 bits (1124), Expect = e-122
 Identities = 266/620 (42%), Positives = 312/620 (50%), Gaps = 63/620 (10%)

Query: 304 PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 363
           PG     G+PG  G+ G PG  GL G  G  G  G  G+KGE G+PG+ GFPG       
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPG-----VR 297

Query: 364 GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 423
           G  G  G  GELG  G  GD G +G  GP GPPG                  P   S + 
Sbjct: 298 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPG-----------------LPGTTSLFT 340

Query: 424 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 483
             P M G +G KGE G+PG  G  G +G  GELG  G  GPPGA+G  G  G  G  G  
Sbjct: 341 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400

Query: 484 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 543
           GA G  G PGP G PG+ G  G RG PG+ G +G++GA G  G PG  GP+GD G PG+ 
Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460

Query: 544 GRDGI--PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMG 601
           G  G    G PG +G PG PGP G  G +G PG+PG PG++G  G  G  G PG  G  G
Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPG 519

Query: 602 NSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG 661
           + G PG +G PG  GP+GP G  G    L P G   L  K      P  PG PG PGLPG
Sbjct: 520 DKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP-GDINLLAKDVCNDCP--PGPPGLPGLPG 576

Query: 662 MKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRG 721
            KGD+GV G+PG +G +G  GE G  G  G  G  G  G +G  G  GE G +G +G  G
Sbjct: 577 FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG 636

Query: 722 LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA--PTDQHIKQVCMRVIQEHFAEMAA 779
           +PG  GP G PGP G  G  GA G PG+QG PG+   P  Q                   
Sbjct: 637 VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ------------------- 677

Query: 780 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 839
                  G +GLPG PG  G  G  G+ G PG+ G  G PG+ GP GA   RGP G  G 
Sbjct: 678 -------GPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---RGPPGFKGH 727

Query: 840 KGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            G+ G PG  P G  GA+GLPG  G    G++G  G  GP G  G  G PG  G PG PG
Sbjct: 728 TGDSGAPG--PRGESGAMGLPGQEGLP--GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 783

Query: 900 FCEPASCTMQAGQRAFNKGP 919
              P+    Q G +  N  P
Sbjct: 784 EPGPSGTPGQKGSKGENGSP 803



 Score =  339 bits (870), Expect = 6e-93
 Identities = 234/608 (38%), Positives = 287/608 (47%), Gaps = 133/608 (21%)

Query: 375 LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA 434
           L  +GP  DP      G  G  G   T        + P++  P  S    +P   GH+ +
Sbjct: 168 LDLLGPRTDPWENVDQGAQGACGRGNT-------SVLPSSVAPQCS----MPKGTGHEFS 216

Query: 435 KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 494
                  G QG   +  D      + A+  PG + L G  G  G+ G  G  GL GE G 
Sbjct: 217 AAL----GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGE 272

Query: 495 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD---------GR 545
           QGL G PG++G+ G PG  G  G RG +G +G       KG+ GLPG+          G 
Sbjct: 273 QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG------EKGELGLPGLKGDRGEKGEAGP 326

Query: 546 DGIPGMPGT----------------KGEPGKPGPPGDAGLQGLP------GVPGIPGAKG 583
            G PG+PGT                KGE G PG PG+ GLQG P      G  G PGAKG
Sbjct: 327 AGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 386

Query: 584 VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGELGPVGSPGLPG 640
             G  G+ GA G PG  G+ G PG  GPPG VG  G +G P   G RGE G  G  G PG
Sbjct: 387 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 446

Query: 641 KLGSLGSPGLPGLPGPPGL-----PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD 695
            +G  G PG PGLPGPPG      PG++G  G+ G  G KG++GA G  G  G RG+ G 
Sbjct: 447 PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG- 505

Query: 696 IGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG------------------------- 730
           IG+ GP G +G PG+   +G  GSRGLPG  GP+G                         
Sbjct: 506 IGVAGPPGPSGPPGD---KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN 562

Query: 731 --PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788
             PPGP G+ G  G  G  GV G PGR  T+                      K+ ++G 
Sbjct: 563 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG---------------------KKGEAGP 601

Query: 789 TGLPGRPGPPGPPGPPGENGFPGQMGIR------GLPGIKGPP---------GALGLRGP 833
            GLPG PG  GP G  GE G  G++G +      G+PG  GPP         G  G  GP
Sbjct: 602 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP 661

Query: 834 KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP 892
            G  G  G+ GPPG +GP+GLP   G+PG+ G    GR+G+ G  G PG AG PG+PGP 
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLP---GIPGEEG--KEGRDGKPGPPGEPGKAGEPGLPGPE 716

Query: 893 GPPGLPGF 900
           G  G PGF
Sbjct: 717 GARGPPGF 724



 Score =  241 bits (614), Expect = 3e-63
 Identities = 153/407 (37%), Positives = 182/407 (44%), Gaps = 100/407 (24%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
            +G PG++GPPGP GP G+PGI G +G  G  G PGPPG  G+ G+PG PG  G  G  G 
Sbjct: 665  QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 724

Query: 328  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----------GIPGPPGPPGTAGLPGELGR 377
             G  G  G+ G +G+ G  G+PG  G PG+          G  GP GPPG  G PG  G 
Sbjct: 725  KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGE 784

Query: 378  VGPVGDPGRRG---------------PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 422
             GP G PG++G               P GPPG PG +G  G  +G P  P    PG  G 
Sbjct: 785  PGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPG-KEGVPGKPGE--PGFKGE 841

Query: 423  PGLPGMRGHKG---AKGEIGEPGRQGHKGEEG---DQGELGEVGAQGPPGAQGLRGITGI 476
             G PG++G KG    KG+ G+PG  GHKG  G    QG  GE G  GPPG  G  G  G+
Sbjct: 842  RGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGL 901

Query: 477  VGDK--------------------------------------------GEKGARGLDGEP 492
             G+                                             G  G  GL G  
Sbjct: 902  RGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRA 961

Query: 493  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG-----------LPGPKGDTG--- 538
            GP G PG PG  G  GP G  GPKG+RGA+G  G PG           +PG  G+ G   
Sbjct: 962  GPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAK 1021

Query: 539  --LPGVDGRDGI------PGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
              LPG+ G  G       PG+PG  G PG+  P   A    L   PG
Sbjct: 1022 DGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1068



 Score =  227 bits (579), Expect = 3e-59
 Identities = 157/430 (36%), Positives = 189/430 (43%), Gaps = 49/430 (11%)

Query: 508 GPPGEAGPKGDRGAEGARG------IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKP 561
           GP  +     D+GA+GA G      +P    P+    +P   G +    + GT+G   + 
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQ--CSMPKGTGHEFSAAL-GTQGPADQR 228

Query: 562 GPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG---QMGNSGKPGQQGPPGEVGPR 618
                + +      PG+    G  GE+G  G PGKPG   ++G  G  G+ G  GE G  
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 288

Query: 619 GPQGLPGSRGELGPVGSPG---LPGKLGSLGSPGLPGLPGPPGLPGMKG----DRGVVGE 671
           G  G PG RGE G  G  G   LPG  G  G  G  G  GPPGLPG          + GE
Sbjct: 289 GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE 348

Query: 672 PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGP 731
            GPKGE+G  G  GE G +G  G++G  GP G  G  G+ G  G  G+ G PG  G  G 
Sbjct: 349 QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 408

Query: 732 PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 791
           PGP G  G  GA GL G  G  G                     E  A+ +    G  G 
Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGER------------------GEKGAAGEEGSPGPVGP 450

Query: 792 PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPN 851
            G PG PG PGPPG+ G  G+ G+RG PG+ GP G  G RG  G  G  G RG PG G  
Sbjct: 451 RGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVA 509

Query: 852 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 911
           G PG  G PGD         G  G RG PG    PG  GP G  GL     P    + A 
Sbjct: 510 GPPGPSGPPGD--------KGSPGSRGLPG---FPGPQGPAGRDGLSSLLSPGDINLLAK 558

Query: 912 QRAFNKGPDP 921
               +  P P
Sbjct: 559 DVCNDCPPGP 568


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  548 bits (1413), Expect = e-156
 Identities = 330/763 (43%), Positives = 384/763 (50%), Gaps = 147/763 (19%)

Query: 268 RGPPGEQGPPGPPGPPGVPGI---------------DGIDGDRGPKGPPGPPGPAGEPGK 312
           +GPPGE G  GP GPPG PG                 G  G+RG  GPPG  GPAG PG 
Sbjct: 200 QGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF 259

Query: 313 P---------------GAPGKPGTPGADGLTGPDGSPGSIGSK---GQKGEPGVPGSRGF 354
           P               G  G PG  G +GL G +G+PG +G +   G++G PG+PG+ G 
Sbjct: 260 PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319

Query: 355 PGR-------GIPGPPGPPGTAGLPGE---LGRVGPVGDPGRRGPPGPPGPPGPRGTIGF 404
            G        G PGPPGPPGTAG PG     G VGP G PG  G PG  G PGP+G  G 
Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG- 378

Query: 405 HDGDPLCP--NACPPGR-----SGYPGLPGMRGHK------------GAKGEIGEPGRQG 445
             G P  P  N  P G+     +G PG PG+ G +            G +G  GEPG+ G
Sbjct: 379 AQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 446 HKGEEGDQGELGEVGAQGPPGAQ---------GLRGITGIVGDKGEKGARGLDGEPGPQG 496
            KGE G +GE GE G  G PGA+         G  G  G+ G  GE+GA G  G  GP G
Sbjct: 439 AKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498

Query: 497 LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKG 556
           +PG  G  G+RG PG AGP+G  G  G  G+PG PG +G  G PG  G DG PG PG++G
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQG 558

Query: 557 EPGKPGPPGDAGLQGLPGVPGIPGAK------GVAGEKGSTGAPGKPGQMGNSGKPGQQG 610
           E G+PGPPG +G +G PGV G PG K      G  GE+G  G PG  G  G +G+ G QG
Sbjct: 559 ESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQG 618

Query: 611 PPGEV------------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP---------G 649
           PPG              GP+G QGLPG+ G  G  G PG PG  G  G+P         G
Sbjct: 619 PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAG 678

Query: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER---------GELGDIGLPG 700
            PG  GPPGL G  G RG  G PGP+G +GA+G  G  G           GE G +G PG
Sbjct: 679 APGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738

Query: 701 PKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGRAP 757
           PKG  G PG PG  G  G  G  G  GP GPPGP G    +GE GA GLPG+ GP G +P
Sbjct: 739 PKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRG-SP 797

Query: 758 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
            ++                     +    G  G PG PG  G PG  GE G PG+ G  G
Sbjct: 798 GERG--------------------ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837

Query: 818 LPGIKGPPGALGLRGPKGDLGEKGERGPP-GRGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            PG+ GPPG  G  GP G  G KGERG P G G  G PGA GLPG P        G +G 
Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPP--------GSNGN 889

Query: 877 RGPPGVAGIPGVPGPPGP------PGLPGFCEPASCTMQAGQR 913
            GPPG +G PG  GPPGP      PG PG   P     Q G++
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK 932



 Score =  530 bits (1365), Expect = e-150
 Identities = 325/730 (44%), Positives = 366/730 (50%), Gaps = 117/730 (16%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK------PGT 321
            RG PGE+G PG PG  G  G DG  G  G  GPPGPPG AG PG PGA G+      PG+
Sbjct: 302  RGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGS 361

Query: 322  PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPP------GPPGTAGL 371
             GA G  G  G  G  G++G  G PG+ GS G  G     GIPG P      GPPG AG 
Sbjct: 362  NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA 421

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA-------CPPGRSGYPG 424
             G  G  G  G+PG+ G  G PGP G RG  G     P  P A         PG  G  G
Sbjct: 422  NGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI----PGVPGAKGEDGKDGSPGEPGANG 477

Query: 425  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 484
            LPG  G +GA G  G  G  G  GE+G  GE G  G  GP GA G  G  G+ G  G +G
Sbjct: 478  LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRG 537

Query: 485  ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDG 544
              G  G PG  G PG PG QG+ G PG  GP G RG     G+ G PGPKG+ G PG +G
Sbjct: 538  MPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP---GVMGFPGPKGNDGAPGKNG 594

Query: 545  RDGIPGMPGTKGEPGK---------------------PGPPGDAGLQGLPGVPGIPGAKG 583
              G PG PG +G PGK                      GPPG  GLQGLPG  G PG  G
Sbjct: 595  ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654

Query: 584  VAGE---KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPG 640
              GE   KG  GAPG PG  G++G PG++GPPG        G PG RG  GP   PG  G
Sbjct: 655  KPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLA------GAPGLRGGAGP---PGPEG 705

Query: 641  KLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQ------GASGEEGEAGERGELG 694
              G+ G PG PG  G PGL GM G+RG +G PGPKG++      GA G  G+ G RG  G
Sbjct: 706  GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765

Query: 695  DIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGPRGPPGP----------------- 734
             IG PGP G  G+ GE   PGL G  G RG PG  G  GPPGP                 
Sbjct: 766  PIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG 825

Query: 735  -RGVQGEQGATGLPGVQGPPGRA-----PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788
             RG  GE+G  G PGV GPPG +     P  Q +K                       GA
Sbjct: 826  ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK--------GERGSPGGPGAAGFPGA 877

Query: 789  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG- 847
             GLPG PG  G PGPPG +G PG+ G  G  G  G PG+ G+ GPKGD G+ GE+G PG 
Sbjct: 878  RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937

Query: 848  RGPNGLPGAIGL------------PGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGP 894
            +GP G PG +G+            PG PGP  S G  G  GE G PG  G+ G  GPPGP
Sbjct: 938  QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGP 997

Query: 895  PGLPGFCEPA 904
             GLPG    A
Sbjct: 998  QGLPGLAGTA 1007



 Score =  525 bits (1352), Expect = e-149
 Identities = 317/686 (46%), Positives = 349/686 (50%), Gaps = 89/686 (12%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            G  G +GPPGP G  G PG+ G  G+ G  G  G PGP GE G+ G PG PG  G DG  
Sbjct: 408  GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467

Query: 329  GPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 387
            G  G PG+ G  G  GE G PG RG  G  GIPG  GP G  G PG  G  G  G+PGR 
Sbjct: 468  GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 388  GPPGPPGPPGPRGTIGF--HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 445
            G PG PG  G  G+ G    DG P  P +   G SG PG PG  G +G  G +G PG +G
Sbjct: 528  GVPGGPGMRGMPGSPGGPGSDGKPGPPGS--QGESGRPGPPGPSGPRGQPGVMGFPGPKG 585

Query: 446  HKGEEGDQGELGEVGA---QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 502
            + G  G  GE G  G    QGPPG  G  G  G  G  G  G +G  G PGPQGL G PG
Sbjct: 586  NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG 645

Query: 503  D---QGQRGPPGEAGPKGDRGAEGA------RGIPGLPGPKGDTGLPGVDGRDGIPGMPG 553
                 G+ G PGE GPKGD GA GA       G PG  GP G  G PG+ G  G PG  G
Sbjct: 646  TGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG 705

Query: 554  TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPG 613
             KG  G PGPPG AG  GL G+PG  G  G  G KG  G PG PG  G  GK G +GP G
Sbjct: 706  GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765

Query: 614  EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 673
             +GP GP G PG +GE    G+PGLPG  G  GSPG  G  GPPG  G  G  G  GEPG
Sbjct: 766  PIGPPGPAGQPGDKGE---GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPG 822

Query: 674  PKGEQGASGEEGEA------------------GERGELGDIGLPGPKGSAGNPGEPGLRG 715
             KGE+GA GE+GE                   G +G  G+ G PG  G+AG PG  GL G
Sbjct: 823  GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG 882

Query: 716  PEGSRGLPGVEGPRGPP---GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
            P GS G PG  GP G P   GP G  G  GA G PGV GP G A                
Sbjct: 883  PPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDA---------------- 926

Query: 773  HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
                          G  G PG  GPPG PGP G  G  G  G+ G PG+ GP G+ G +G
Sbjct: 927  -----------GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975

Query: 833  PKGDLGE------KGERGPPGRGPNGLPGAIGLPGDPG----PASYGRNGRD-------- 874
             KG+ G+       GERGPP  GP GLPG  G  G+PG    P S G  GRD        
Sbjct: 976  VKGESGKPGANGLSGERGPP--GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033

Query: 875  -GERGPPGVAGIPGVPGPPGPPGLPG 899
             GE G PG  G PG PGPPGP G  G
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAG 1059



 Score =  520 bits (1339), Expect = e-147
 Identities = 317/705 (44%), Positives = 359/705 (50%), Gaps = 60/705 (8%)

Query: 269  GPPGEQGPPG---PPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT---P 322
            G  GE+G PG   P GP G+PG  G  G+RG  GP GP G AGEPG+ G PG PG    P
Sbjct: 480  GAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMP 539

Query: 323  GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPV 381
            G+ G  G DG PG  GS+G+ G PG PG  G  G+ G+ G PGP G  G PG+ G  G  
Sbjct: 540  GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599

Query: 382  GDPGRRGPPG------PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G PG +GPPG      P GPPGP G  G   GD       PPG  G  GLPG  G  G  
Sbjct: 600  GGPGPQGPPGKNGETGPQGPPGPTGP-GGDKGD-----TGPPGPQGLQGLPGTGGPPGEN 653

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGA---QGPPG---AQGLRGITGIVGDKGEKGARGLD 489
            G+ GEPG +G  G  G  G  G+ GA   +GPPG   A GLRG  G  G +G KGA G  
Sbjct: 654  GKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPP 713

Query: 490  GEPGPQGLPGAPGDQGQRGPPGEAGPKGDRG---AEGARGIPGLPGPKGDTGLPGVDGRD 546
            G PG  G PG  G  G+RG  G  GPKGD+G     GA G+PG  GP+G TG  G  G  
Sbjct: 714  GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 547  GIPGMPGTKGEPGKPG------PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 600
            G PG  G  G PG PG       PG+ G  G PG  G PGA G  GE G  G  G PG+ 
Sbjct: 774  GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833

Query: 601  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 660
            G  G PG  GPPG  GP GP G  G +GE G  G PG  G  G+ G PG PG  G PG P
Sbjct: 834  GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP 893

Query: 661  GMKGDRGVVGEPGPKGEQGA------SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR 714
            G  G  G  G PGP G  GA      SG +G+AG+ GE G  G  GP G+ G  G  G+ 
Sbjct: 894  GPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGIT 953

Query: 715  GPEGSRGLPGVEGPRGPPGPRGVQGEQG---ATGLPGVQGPPG---------RAPTDQHI 762
            G  G  G PG+ GPRG PGP+GV+GE G   A GL G +GPPG          A      
Sbjct: 954  GARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD 1013

Query: 763  KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP------PGENGFPGQMGIR 816
                   +            R ++G+ G PG PG PGPPGP       G+ G  G  G  
Sbjct: 1014 GNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPA 1073

Query: 817  GLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY-GRNGRD 874
            G PG  G  GA G +GP+GD GE GERG  G +G  G PG  G PG PGPA   G  G  
Sbjct: 1074 GAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSP 1133

Query: 875  GERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
            G  GP G  G  G PG  G  G PG   P       G+R     P
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178



 Score =  519 bits (1337), Expect = e-147
 Identities = 317/721 (43%), Positives = 365/721 (50%), Gaps = 100/721 (13%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGV---PGIDGIDGD---RGPKGPPGPPGPAGEPGKPG 314
            P+    E+GP GE+G PGP GP G    PG DG+ G    RG  G PG PG  G+PG PG
Sbjct: 496  PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555

Query: 315  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG-FPGRGIPGPPGPPGTAGLPG 373
            + G+ G PG  G +GP G PG +G  G KG  G PG  G   G G PGP GPPG  G  G
Sbjct: 556  SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG 615

Query: 374  ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-----HDGDPLCPNACPPGRSGYPGLPGM 428
              G  GP G  G +G  GPPGP G +G  G       +G P  P   P G +G PG PG 
Sbjct: 616  PQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPG--PKGDAGAPGAPGG 673

Query: 429  RGHKGAKGE------IGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDK-- 480
            +G  GA GE       G PG +G  G  G +G  G  G  GPPGA G  G+ G+ G++  
Sbjct: 674  KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733

Query: 481  -GEKGARGLDGEPGPQGLPGAPGDQGQR------GPPGEAGPKGDRGAEGARGIPGLPGP 533
             G  G +G  GEPG  G  G PG  G R      GPPG AG  GD+G  GA G+PG+ GP
Sbjct: 734  LGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGP 793

Query: 534  KGD------------TGLPGVDGRDGIP------GMPGTKGE---PGKPGPPGDAGLQGL 572
            +G              G PG  G++G P      G PG KGE   PG  GPPG +G  G 
Sbjct: 794  RGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGP 853

Query: 573  PGVPGI------PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP---QGL 623
            PG  G+      PG  G AG  G+ G PG PG  GN G PG  G PG+ GP GP    G 
Sbjct: 854  PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913

Query: 624  PGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE---PGPKGE--- 677
            PGS G  GP G  G PG+ GS G+ G PG PGP G+ G+ G RG+ G    PGP+G    
Sbjct: 914  PGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGP 973

Query: 678  QGASGEEGEAGERGELGDIGLPGPK---GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            QG  GE G+ G  G  G+ G PGP+   G AG  GEPG  G  GS GLPG +G  G  G 
Sbjct: 974  QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033

Query: 735  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794
            RG  G  GA G PG  GPPG                         S  R +SG  G  G 
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPV------------------GPAGKSGDRGESGPAGPAGA 1075

Query: 795  PGP------PGPPGPPGENGFPGQMGI------RGLPGIKGPPGALGLRGPKGDLGEKGE 842
            PGP      PGP GP G+ G  G+ G       RG PG  G PG+ G  G +G +G  G 
Sbjct: 1076 PGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGP 1135

Query: 843  RGPPGR-GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900
             GP G  GP+G PG  G  G PGP    G  G  GERG  G  G PG PGPPGPPG PG 
Sbjct: 1136 AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGP 1195

Query: 901  C 901
            C
Sbjct: 1196 C 1196



 Score =  506 bits (1304), Expect = e-143
 Identities = 314/756 (41%), Positives = 364/756 (48%), Gaps = 142/756 (18%)

Query: 259 ITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 318
           + P   T    PP  QGP GP G PG               PPG PG  G+PG PG PG 
Sbjct: 87  VCPQPPTAPTRPPNGQGPQGPKGDPG---------------PPGIPGRNGDPGIPGQPGS 131

Query: 319 PGTPGADGL-----TGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLP 372
           PG+PG  G+     TGP        S   K    V G  G+PG  G PGPPGPPGT+G P
Sbjct: 132 PGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHP 191

Query: 373 GELGRVG---PVGDPGRRGPPGPPGPPG---PRGTIGFHDGDPLCPNAC-------PPG- 418
           G  G  G   P G+PG+ GP GPPGPPG   P G  G  DG+   P          PPG 
Sbjct: 192 GSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAG-KDGESGRPGRPGERGLPGPPGI 250

Query: 419 --RSGYPGLPGMRGHKG------AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470
              +G PG PGM+GH+G       KGE G PG +G  G  G+ G  G +G +G PG +G 
Sbjct: 251 KGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGR 310

Query: 471 RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 530
            G+ G  G +G  GARG DG+PGP G PG  G  G  G  GE GP G  G+ GA G  G 
Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370

Query: 531 PGPKGDTGLPGVDGRDGIPGMPGTKGE------PGKP------GPPGDAGLQGLPGV--- 575
           PGP+G  G  G  G  GI G PG KGE      PG P      GPPG AG  G PG+   
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430

Query: 576 ---------------------PGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
                                 GIPG  G  GE G  G+PG+PG  G  G  G++G PG 
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490

Query: 615 VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP---GLPGMKGDRGVVGE 671
            GP GP G+PG +G  G  G+PG  G  G+ G PG  G+PG P   G+PG  G  G  G+
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 672 PGPKGEQGASGE---EGEAGERGELGDIGLPGPKGSAGNPGE------PGLRGPEGSRGL 722
           PGP G QG SG     G +G RG+ G +G PGPKG+ G PG+      PG  GP+G  G 
Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 723 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
            G  GP+GPPGP G  G++G TG PG QG  G   T                        
Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG----------------------- 647

Query: 783 RPDSGATGLPGRPGP---PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 839
               G  G PG PGP    G PG PG  G  G  G RG PG+ G PG  G  GP G  G 
Sbjct: 648 -GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGG 706

Query: 840 KGERGPPG-RGPNGLPGAIGLPGD----------------PGPASYGRNGRDGER----- 877
           KG  GPPG  G  G PG  G+PG+                 GP + G  G+DG R     
Sbjct: 707 KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGP 766

Query: 878 -GPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 912
            GPPG AG PG  G  G PGLPG   P     + G+
Sbjct: 767 IGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802



 Score =  471 bits (1213), Expect = e-132
 Identities = 291/668 (43%), Positives = 326/668 (48%), Gaps = 97/668 (14%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            G  GE+G PG PGP G PG +G  G +GP GP GP G  G+ G PG  G  G PG  G  
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 329  GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 388
            G +G PG  G KG  G PG PG +G    G PG  GPPG AG PG  G  GP G  G +G
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKG--DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 389  PPGPPGPPGPRGTIGFHD-----------------GDPLCPNAC-------PPGRSGYPG 424
              GPPGPPG  GT G                    G+P  P A        P G +G  G
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 425  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 484
             PG  G  G KGE G PG  G  G  G  GE GE G  GP G  G  G  G  G KGE+G
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 485  ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDG 544
            A G  GE GP G+ G PG  G  GPPG  G KG+RG+ G  G  G PG +G   LPG  G
Sbjct: 829  APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG---LPGPPG 885

Query: 545  RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG---EKGSTGA---PGKPG 598
             +G PG PG  G PGK GPPG AG  G PG PG+ G KG AG   EKGS GA   PG PG
Sbjct: 886  SNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945

Query: 599  QMGNSGKPGQQG---PPGEVGPRG---PQGLPGSRG---------ELGPVGSPGLPGKLG 643
             +G +G  G +G   PPG  GPRG   PQG+ G  G         E GP G  GLPG  G
Sbjct: 946  PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 644  SLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKG 703
            + G PG  G PG  GLPG  G  G  G+ G  G  GA G  G  G  G +G  G  G +G
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 704  SAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---RGVQGEQGATGLPGVQGPPGR-APTD 759
             +G  G  G  GP GSRG PG +GPRG  G    RG  G +G  G PG  G PG   P  
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125

Query: 760  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 819
            Q                   ++  P  G  G  G  GP GPPG  G +G PG +      
Sbjct: 1126 QQ-----------------GAIGSP--GPAGPRGPVGPSGPPGKDGTSGHPGPI------ 1160

Query: 820  GIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGP 879
               GPP      GP+G+ GE+G  G PG    G PG  G PG PGP         G  G 
Sbjct: 1161 ---GPP------GPRGNRGERGSEGSPGH--PGQPGPPGPPGAPGPCC-------GGVGA 1202

Query: 880  PGVAGIPG 887
              +AGI G
Sbjct: 1203 AAIAGIGG 1210



 Score =  457 bits (1177), Expect = e-128
 Identities = 269/621 (43%), Positives = 305/621 (49%), Gaps = 83/621 (13%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    P     + GPPG QG  G PG  G PG +G  G+ GPKG  G PG  G  G  GA
Sbjct: 620  PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA 679

Query: 316  PGK---PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGP 365
            PG+   PG  GA GL G  G PG  G KG  G PG PG+ G PG       RG  G PGP
Sbjct: 680  PGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGP 739

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG--FHDGDPLCPNAC-------- 415
             G  G PG  G  G  G  G RGP GP GPPGP G  G     G P  P           
Sbjct: 740  KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE 799

Query: 416  -----PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470
                 PPG +G+PG PG  G  G KGE G PG +G  G  G  G  G  G  GPPG QG+
Sbjct: 800  RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGV 859

Query: 471  RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 530
            +G  G  G  G  G  G  G PGP G  G PG  G  G PG+ GP G  G  GA G PG+
Sbjct: 860  KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGV 919

Query: 531  PGPKGDTGLPGVDGRDGIPGMPGT---------------KGEPGKPGPPGDAGLQGLPGV 575
             GPKGD G PG  G  G  G PG                 G PG PGP G  G QG+ G 
Sbjct: 920  SGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE 979

Query: 576  PGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGS 635
             G PGA G++GE+G  G  G PG  G +G+PG+ G PG  G  G  G PG +G+ G  GS
Sbjct: 980  SGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGS 1039

Query: 636  PGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR------GVVGEPGPKGEQGASGEEGEAGE 689
            PG P      G+PG PG PGP G  G  GDR      G  G PGP G +GA G +G  G+
Sbjct: 1040 PGAP------GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093

Query: 690  RGELGD---IGLPGPKGSAGNPGEPGLRGPEGSRGL---PGVEGPRGPPGPRGVQGEQGA 743
            +GE G+    G+ G +G  GNPG PG  GP G +G    PG  GPRGP GP G  G+ G 
Sbjct: 1094 KGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153

Query: 744  TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP 803
            +G PG  GPPG                            R + G+ G PG PG PGPPGP
Sbjct: 1154 SGHPGPIGPPGPRG------------------------NRGERGSEGSPGHPGQPGPPGP 1189

Query: 804  PGENG-FPGQMGIRGLPGIKG 823
            PG  G   G +G   + GI G
Sbjct: 1190 PGAPGPCCGGVGAAAIAGIGG 1210



 Score =  375 bits (963), Expect = e-103
 Identities = 229/559 (40%), Positives = 268/559 (47%), Gaps = 71/559 (12%)

Query: 398 PRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG 457
           P   I F +   +CP   PP     P  P  +G +G KG+ G PG  G  G+ G  G+ G
Sbjct: 75  PNPEIPFGECCAVCPQ--PPTAPTRP--PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130

Query: 458 EVGAQGPPG--------------------AQGLRGITGIVGDKGEKGARGLDGEPGPQGL 497
             G+ GPPG                     +    + G+ G  G  G  G  G PG  G 
Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGH 190

Query: 498 PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557
           PG+PG  G +GPPGE G  G  G          PGP G  G  G  G+DG  G PG  GE
Sbjct: 191 PGSPGSPGYQGPPGEPGQAGPSGP---------PGPPGAIGPSGPAGKDGESGRPGRPGE 241

Query: 558 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617
            G PGPPG  G  G+PG PG+ G +G  G  G  G  G PG  G +G PG+ G P   GP
Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP---GP 298

Query: 618 RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP---GLPGMKGDRGVVGEPGP 674
            GP+G PG RG  G  G+ G  G  G+ GS G PG PGPP   G PG  G +G VG  G 
Sbjct: 299 MGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS 358

Query: 675 KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            G  GA G+ GE G +G  G  G PGP G  G+PG  G  GP G  G PG+ G RGPPGP
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGP 418

Query: 735 RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP-- 792
            G     GA GL G  G PG+                    E     +R ++G  G+P  
Sbjct: 419 AGA---NGAPGLRGGAGEPGKNGAK---------------GEPGPRGERGEAGIPGVPGA 460

Query: 793 -GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGP 850
            G  G  G PG PG NG PG  G RG PG +GP G  G+ G KG  GE+G  GP G RG 
Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 851 NGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGP------PGLPGF 900
            G PG  G+PG PG    P S G  G DG+ GPPG  G  G PGPPGP      PG+ GF
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGF 580

Query: 901 CEPASCTMQAGQRAFNKGP 919
             P       G+     GP
Sbjct: 581 PGPKGNDGAPGKNGERGGP 599



 Score =  351 bits (900), Expect = 2e-96
 Identities = 211/480 (43%), Positives = 242/480 (50%), Gaps = 65/480 (13%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314
            +P +  P   T   GPPG  G PG  G  G PG+ GI G RG  G  G  GP G  G PG
Sbjct: 754  VPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG 813

Query: 315  APGK---------------------PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG 353
            APG+                     PG  G  G +GP G PG  G KG++G PG PG+ G
Sbjct: 814  APGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873

Query: 354  FPG-RGIPGP------PGPPGTAGLPGELGRVGPVGD------PGRRGPPGPPGPPGPRG 400
            FPG RG+PGP      PGPPG +G PG+ G  GP G+      PG  GP G  G PG +G
Sbjct: 874  FPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG 933

Query: 401  TIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVG 460
            + G   G P  P   P G +G  G  G+ G  G  G  G PG QG KGE G  G  G  G
Sbjct: 934  SPG-AQGPPGAPG--PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSG 990

Query: 461  AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRG 520
             +GPPG QGL G+ G  G+ G  G  G DG PG  G PG  GD+G+ G P         G
Sbjct: 991  ERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSP---------G 1041

Query: 521  AEGARGIPGLPGP------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG 574
            A GA G PG PGP       GD G  G  G  G PG  G++G PG  GP GD G  G  G
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERG 1101

Query: 575  VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVG 634
              GI G +G  G  G+ G+PG  GQ G  G PG  GP G VGP GP G  G+ G  GP+G
Sbjct: 1102 AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIG 1161

Query: 635  SP---GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP-KGEQGASGEEGEAGER 690
             P   G  G+ GS GSPG PG PGPPG P         G PGP  G  GA+   G  GE+
Sbjct: 1162 PPGPRGNRGERGSEGSPGHPGQPGPPGPP---------GAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  152 bits (383), Expect = 2e-36
 Identities = 98/239 (41%), Positives = 110/239 (46%), Gaps = 36/239 (15%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314
            LP R        +RG  G  G PG PG PG PG  G  G  G +G  GP GPAG PG  G
Sbjct: 1021 LPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAG 1080

Query: 315  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE 374
            + G P         GP G  G  G  G++G  G+ G RGFPG   PG PG PG AG  G 
Sbjct: 1081 SRGAP---------GPQGPRGDKGETGERGAAGIKGHRGFPGN--PGAPGSPGPAGQQGA 1129

Query: 375  LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA 434
            +G  GP G    RGP GP GPPG  GT                  SG+PG  G  G +G 
Sbjct: 1130 IGSPGPAGP---RGPVGPSGPPGKDGT------------------SGHPGPIGPPGPRGN 1168

Query: 435  KGEIGEPGRQGHKGEEGDQGELGEVGAQGP-PGAQGLRGITGIVGDKGEKGARGLDGEP 492
            +GE G  G  GH G+ G     G  GA GP  G  G   I GI G+K    A     EP
Sbjct: 1169 RGERGSEGSPGHPGQPGPP---GPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEP 1224


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score =  548 bits (1412), Expect = e-156
 Identities = 361/931 (38%), Positives = 443/931 (47%), Gaps = 129/931 (13%)

Query: 74  IQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQI 133
           ++R  G     VAY++        PTR L+P G P+++S LT  R           ++  
Sbjct: 47  VRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSA 106

Query: 134 QDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAA---FSNLSSLFDSQWHKIMIGVERS 190
           Q   G  Q+G+++    + V F Y+   G  Q  +   F  LS L D +WH++ + V+  
Sbjct: 107 Q---GVRQLGLELG---RPVRFLYEDQTGRPQPPSQPVFRGLS-LADGKWHRVAVAVKGQ 159

Query: 191 SATLFVDCNR--IESLPIKPRGPIDIDGFAVLG--------------KLADNPQVSVPFE 234
           S TL VDC +     LP   R  +D  G  + G              +LA  P V   +E
Sbjct: 160 SVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYE 219

Query: 235 -LQWMLIHCDP---LRPRRETCH-------ELPARITPSQTTDE--------RGPPGE-- 273
             +   + C+     RP+ +  H       + P+R+   Q  +         RG  GE  
Sbjct: 220 SCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQAAHGPRGLKGEKG 279

Query: 274 -----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGKPGAPGKP 319
                      +GPPGP GP G+ G  GI G+ GP G PG   PPG AG PG  GAPG P
Sbjct: 280 EPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPP 339

Query: 320 GT----PGADGLTGPDGSPGSIGSKGQKGE---------PGVPGSRGFPGRGIPGPPGPP 366
           GT    P   G  G D  P     + Q             G PG  G+ GR  PGP G P
Sbjct: 340 GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQP 397

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSG 421
           G+ GL GE G +GP G  G +G  GPPG  G RG  G        GDP        G  G
Sbjct: 398 GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG--DRGFDG 455

Query: 422 YPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQG 469
            PGLPG +GH+G  G  G PG  G  GE GD GE+G             +G +GPPG  G
Sbjct: 456 LPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPG 515

Query: 470 LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
             G+ G+ G +G KG+ G  GEPGP G  G PG QG  GP G  GP G++G +G  G+PG
Sbjct: 516 PPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPG 575

Query: 530 LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 589
           +PG  G    PG  G++G PG  G +G  G  GP G  G +G+ GV GI G KG  GEKG
Sbjct: 576 MPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG 632

Query: 590 STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
             G PG  G +G  G  G+ G PG  G  GP+   G +G  GP G PG PG +G  G  G
Sbjct: 633 EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE---GPKGRTGPTGDPGPPGLMGEKGKLG 689

Query: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
           +PGLPG PG  G KG  G  G PG  GE+GA G  G++G RGE       GP G  G  G
Sbjct: 690 VPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGE------RGPTGPRGQRG 743

Query: 710 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
             G  G  G++G  G +GP GPPG RG+ G QG  G PG +GPPG    D        R 
Sbjct: 744 PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 803

Query: 770 IQEHFAEMAASLKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 822
            +  F         P        +G TG  G  G PGPPGPPGE G PG  G  G  G  
Sbjct: 804 -EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 823 GPPGALGLRGPKGDLGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS----Y 868
           GPPGA G  GP G  G  GERG PG           GP+G PG  G PG+ G A      
Sbjct: 863 GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI 922

Query: 869 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
           G  GR G +GPPG AG  GVPG  GP G  G
Sbjct: 923 GPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 953



 Score =  517 bits (1331), Expect = e-146
 Identities = 310/701 (44%), Positives = 360/701 (51%), Gaps = 100/701 (14%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            E GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G
Sbjct: 537  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPG 373
              GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG
Sbjct: 597  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPG 656

Query: 374  ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMR 429
              G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  
Sbjct: 657  SRGEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGAS 715

Query: 430  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIV 477
            G KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  
Sbjct: 716  GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQ 775

Query: 478  GDKGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGAR 525
            G  G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G R
Sbjct: 776  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 835

Query: 526  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAK 582
            G PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG K
Sbjct: 836  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 895

Query: 583  GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 642
            G  G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ 
Sbjct: 896  GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 955

Query: 643  GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
            G  G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   
Sbjct: 956  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP--- 1012

Query: 703  GSAGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPP 753
            G+AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPP
Sbjct: 1013 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1072

Query: 754  G----RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
            G    R P                            +GA G  G PG  G  GPPGE G 
Sbjct: 1073 GPPGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 810  PGQM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGL 859
            PG+    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G 
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1164

Query: 860  PGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            PGDPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1165 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1205



 Score =  506 bits (1303), Expect = e-143
 Identities = 299/686 (43%), Positives = 343/686 (50%), Gaps = 65/686 (9%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P   T + G  G  G  GP GPPG  G+ G  G  G  GP GPPGP G+ G PG PG+ G
Sbjct: 744  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 803

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
              G  G TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G 
Sbjct: 804  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGT 858

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
             GDPG   PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G 
Sbjct: 859  KGDPG---PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGS 909

Query: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGL 497
            PG +G  G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G 
Sbjct: 910  PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 969

Query: 498  PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557
            PG  G+ G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G 
Sbjct: 970  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1029

Query: 558  PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617
             G  G  G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G 
Sbjct: 1030 FGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGA 1086

Query: 618  RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGE 677
             GPQG PG  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G 
Sbjct: 1087 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1146

Query: 678  QGASGEEGEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGL 722
            +G +G++G  G  G +G  G PGP               +G  G PG+PG  GP G  G 
Sbjct: 1147 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1206

Query: 723  PGVEGPRGP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFA 775
            PG  G RGP   PG  G QG +GA G PG  G PG+     P     K        +   
Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLR 1261

Query: 776  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 835
             +  S+     G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G
Sbjct: 1262 GLPGSV-----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316

Query: 836  DLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895
            + GEKG+RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP 
Sbjct: 1317 EQGEKGDRGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPK 1363

Query: 896  GLPGFCEPASCTMQAGQRAFNKGPDP 921
            G  G   P     + G +     P P
Sbjct: 1364 GAKGATGPGGPKGEKGVQGPPGHPGP 1389



 Score =  486 bits (1251), Expect = e-137
 Identities = 290/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 323
            +RG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 801  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 860

Query: 324  ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 379
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 861  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 434
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 921  PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978

Query: 435  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 494
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 979  KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1038

Query: 495  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 554
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098

Query: 555  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 671
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218

Query: 672  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 728
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1278

Query: 729  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1279 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1321

Query: 777  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 831
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1369

Query: 832  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 889
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1370 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1427

Query: 890  GPPG 893
            G PG
Sbjct: 1428 GSPG 1431



 Score =  424 bits (1089), Expect = e-118
 Identities = 255/595 (42%), Positives = 296/595 (49%), Gaps = 62/595 (10%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAG 308
            LP       T  + GPPG  G  GP      PG  G+PG  G  G +G +GP GPPGPAG
Sbjct: 849  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908

Query: 309  EPGK------------PGAPGKPGTPGAD------------------------GLTGPDG 332
             PG+            PG PG  G PGA                         GL GP G
Sbjct: 909  SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 968

Query: 333  SPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPG 391
             PG  G  G KGE G PG +G  G +G  GPPGPPG  G  G+ G  G  G+PG RGP G
Sbjct: 969  PPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1028

Query: 392  PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 451
              G  G  GT GF+          PPG  G  GLPG  G KG  G++G  G  G  G  G
Sbjct: 1029 HFGAKGDEGTRGFNG---------PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1079

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---GPQGLPGAPGDQGQRG 508
              G  G  G QGPPG  G  G  G  G+ GE G+ G+ GEP   GP+G  G  G+ GQ G
Sbjct: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1139

Query: 509  PPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
             PG  GPKG  G +G +G PG  G  GD G PG  G  G  G  G +GE G+PG PG  G
Sbjct: 1140 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1199

Query: 569  LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
              G  G PG  G +G AG  GS G  G  G  G+ G  G  G  G VGP GP G PG  G
Sbjct: 1200 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1259

Query: 629  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              G  GS G  G+ G+ G  G PG  GPPGLPG++GD G  GE   KG  G  G  G  G
Sbjct: 1260 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPG 1316

Query: 689  ERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745
            E+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP GP G +G  G  G  G
Sbjct: 1317 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1376

Query: 746  LPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
              GVQGPPG   P  + I+ + +++ ++    +  S    +  A    G PG PG
Sbjct: 1377 EKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1431


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score =  548 bits (1412), Expect = e-156
 Identities = 366/998 (36%), Positives = 467/998 (46%), Gaps = 180/998 (18%)

Query: 42  ELCPKIRIGQDDLPGFDLISQFQV------DKAASRRAIQRVVGSATLQVAYKLGNNVDF 95
           E CP +RI    L  +D I++ +V      D  + RRA        + +  +KLG+ +  
Sbjct: 32  ESCPILRIEGHQLT-YDNINKLEVSGFDLGDSFSLRRAF-----CESDKTCFKLGSALLI 85

Query: 96  RIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVF 155
           R  T  ++P GLPEEYS    FR+  +  K+ W +WQ+ +     Q+ I ++G  + V F
Sbjct: 86  R-DTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKKVVEF 144

Query: 156 SYKGLDGSLQTAAFSN--LSSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPID 213
            ++  +G +    F N  L  LFD QWHK+ I ++    +L++DCN I       +  +D
Sbjct: 145 MFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEKDTVD 204

Query: 214 IDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPARITPSQ---------- 263
             G  V+   A + +  V  EL  + I+C      +ETC E+     P Q          
Sbjct: 205 FHGRTVIATRASDGK-PVDIELHQLKIYCSANLIAQETCCEISDTKCPEQDGFGNIASSW 263

Query: 264 --------------------------TTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRG- 296
                                        E G PG  G PG  G  G PG +G+ G  G 
Sbjct: 264 VTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGF 323

Query: 297 --PKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGS------KGQKGEPGV 348
              KG  G  G  GE G+ G  G+ G P   GL G +G  G +G       KG+KG+ G 
Sbjct: 324 PGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP 383

Query: 349 PGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-- 405
           PG    PG  GI GP GPPG  G  G  G+ GP G PG  GPPGPPG  G   T+G +  
Sbjct: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443

Query: 406 ---DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ 462
               G+         G  G  GLPG  G  G KG+ GEPG    KGE+GD+GE G +G+Q
Sbjct: 444 KDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQ 503

Query: 463 GPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAE 522
           G  G  G  G  G++G  G KG +G  G  GP+G PG  G  G+ G PG+ G KG++G  
Sbjct: 504 GVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDP 563

Query: 523 GA-RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA 581
           G   G PGLPGPKG+ G PG      +PG PG  G PG PGP G  G +GLPGV G PG 
Sbjct: 564 GGIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619

Query: 582 KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 641
            G             P  +G  G+ G QGP GE G +GP+GLPG  G  G  G+ G+PG+
Sbjct: 620 IG-------------PQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGR 666

Query: 642 LGSLGSPGLPGLP----------------------GPPGLPGMKGDRGVVGEP------- 672
            G  G PG PG P                        PGL   KG+ G  GEP       
Sbjct: 667 DGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMA 726

Query: 673 -----GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 727
                GP+G  G  G EG  G +GE G  G+PG KG  G  G PG+ G  G  G PG+ G
Sbjct: 727 RKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMG 786

Query: 728 PRGPPGPRGVQGEQGATGLPGVQGPPG--RAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
             G PGP G +GE+G+ G PG  GPPG    P ++      +  I+              
Sbjct: 787 RTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIK-------------- 832

Query: 786 SGATGLPGRPGPPGPPGP---PGENGFPGQMGIRGL---PGIK------GPPGALGL--- 830
            G   +P  PGPPGPPGP   PG  G PG MG+ GL   PG+K      GPPG  G+   
Sbjct: 833 -GGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGK 891

Query: 831 ---------------RGPKGDLGEKGERGPPGR----GPNGLPGA---IGLPGDPGPASY 868
                          RGP GD+G  G  GP G+    G +G+PGA   +G PGD GP   
Sbjct: 892 PGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGE 951

Query: 869 -------GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
                  G  G  GERG PG+ G+ G  GP GPPG  G
Sbjct: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKG 989



 Score =  481 bits (1238), Expect = e-135
 Identities = 301/760 (39%), Positives = 355/760 (46%), Gaps = 168/760 (22%)

Query: 269  GPPGEQGPPGPPGPPGVPGID--------------------GIDGDRGPKGPPGPPGPAG 308
            GPPG+ GPPGPPGPPG+ GI                     G+ GD+G  G PG PG  G
Sbjct: 415  GPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVG 474

Query: 309  EPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPG 361
              G+ G PG+P T G  G  G  G  GS G KG+ G+PG PG  G PG        G  G
Sbjct: 475  PKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534

Query: 362  PPGPPGTAGLPGELGRVGPVGDPGRRGPPG----PPGPPGPRGTIGFHDGDPLCPNACPP 417
            P GPPG  GLPGE G  G  G  G +G PG    PPG PGP+G  G        P    P
Sbjct: 535  PRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAG-------PPGKSLP 587

Query: 418  GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE--LGEVGAQGP---PGAQGLRG 472
            G  G  G PG  G +G KGE G PG  G  G+ G QG    G  GAQGP   PG QG RG
Sbjct: 588  GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG 647

Query: 473  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---------------------------- 504
            + G+ G  G  G  G+ G  G  GLPG PGD                             
Sbjct: 648  LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLK 707

Query: 505  ------------------------GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL- 539
                                    G RGPPG  G +G +G++G RG PG+PG KGD GL 
Sbjct: 708  SNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQ 767

Query: 540  --------------PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVP-----GIPG 580
                          PG+ GR G PG  G KGE G  GPPG  G  G PG+P     G+  
Sbjct: 768  GIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSS 827

Query: 581  AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPG 640
               + G       PG PG  G  G PG  G PG +G  G +G PG +G+ GP G PG+ G
Sbjct: 828  LYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAG 887

Query: 641  KLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPG 700
              G  G+PG PG+PG PG  G  GD G  G  GP G+ G +G++G  G +G +G  G  G
Sbjct: 888  MSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRG 947

Query: 701  PKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA---- 756
            PKG  G+ G PG RG +G RG PG+ G +G  GP G  G +G+ G PG QGPPG      
Sbjct: 948  PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPG 1007

Query: 757  -PTD--------QHIKQVCMRVIQEHFAEMAASLKRPDSG-ATGLPGRPGPPGPPGPPGE 806
             P D        ++I Q  +R+ +E  A   + LK P +  A    GRPGPPG  G PG 
Sbjct: 1008 IPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP 1067

Query: 807  NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA 866
             G PG                     P+G  G+KGERG PG    GLPG+ GLPG     
Sbjct: 1068 PGDPG---------------------PQGYRGQKGERGEPG---IGLPGSPGLPG----- 1098

Query: 867  SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
                          G+ G PG PGP GPPG  G C P  C
Sbjct: 1099 ----------TSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128



 Score =  474 bits (1219), Expect = e-133
 Identities = 286/713 (40%), Positives = 344/713 (48%), Gaps = 130/713 (18%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
            +G  GE+G  G  G P + G++G +G +G  GP GPPGP GE G  G PG P  PG+ G+
Sbjct: 336  KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGI 395

Query: 328  TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV--------- 378
             GP G PG  G +G++G+ G PG       G PGPPGPPG  G+   LG           
Sbjct: 396  QGPQGPPGKEGQRGRRGKTGPPGK-----PGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450

Query: 379  -----GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKG 433
                 G  GD G  G PG PG  GP+G  G   G+P        G  G PG+ G +G KG
Sbjct: 451  EHEAGGLKGDKGETGLPGFPGSVGPKGQKG-EPGEPFTKG--EKGDRGEPGVIGSQGVKG 507

Query: 434  AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPG 493
              G+ G PG  G  G +G QG  G +G +GPPG  GL G  GI G +G KG +G  G  G
Sbjct: 508  EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565

Query: 494  PQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD------- 546
              G PG PG +G+ GPPG++ P G+ G +G  G PG  GPKG+ GLPGV G         
Sbjct: 566  IIGPPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG 624

Query: 547  -GIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ------ 599
             GIPG  G +G  G+PG  G  GL GLPG PG PG  GV G  G  G PG PG       
Sbjct: 625  IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684

Query: 600  ----------------------MGNSGKPGQQGPP---------GEVGPRGPQGLP---G 625
                                    N G+ G  G P         G++GPRGP G+P   G
Sbjct: 685  LGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREG 744

Query: 626  SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEG 685
             +G  G  G PG+PG+ G  G  G+PG+PG PG  G  G  G  G PGP G +G  G +G
Sbjct: 745  PKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDG 804

Query: 686  EAGERGELGDIGL-----------------------------PGPKGSAGNPGEPGLRGP 716
              G+ G  G  G+                             PGPKG  G  GEPG  G 
Sbjct: 805  PPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGL 864

Query: 717  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776
             G  G PGV+G RGP GP G+ G  G  G PG  G PG                      
Sbjct: 865  PGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPG------------------- 905

Query: 777  MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD 836
                 +R   G  G PG  GP G PG  G++G PG  GI G PG +GP G  G +G  GD
Sbjct: 906  -----ERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD 960

Query: 837  LGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP 889
             G +GERG PG    G+ GAIG  G PG  + G  G  G +GPPG  GIPG+P
Sbjct: 961  RGSQGERGKPGL--TGMKGAIGPMGPPG--NKGSMGSPGHQGPPGSPGIPGIP 1009



 Score =  368 bits (944), Expect = e-101
 Identities = 241/620 (38%), Positives = 274/620 (44%), Gaps = 152/620 (24%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK--------- 318
            +G  GE G PGPPG  G PG+ G  G  G  GP GPPG  G PG+ G PGK         
Sbjct: 503  QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGD 562

Query: 319  -------PGTPGADGLTGP-----------DGSPGSIGSKGQKGEPGVPGSRGFPG---- 356
                   PG PG  G  GP           DG+PG+ G +G KGE G+PG  G PG    
Sbjct: 563  PGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGP 622

Query: 357  --------------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG-PRGT 401
                           G PG  GP G  GLPG  G  G  G PGR G PG PGPPG P   
Sbjct: 623  QGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIAL 682

Query: 402  IGFHDGDPLCPNAC---------------------PPGR------------SGYPGLPGM 428
                D   L  N C                      PG+             G PG+PG 
Sbjct: 683  PLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGR 742

Query: 429  RGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGA 485
             G KG+KGE G PG  G KG+EG QG  G  GA GP G  GL G TG     G KGEKG+
Sbjct: 743  EGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGS 802

Query: 486  RGLDGEPGPQGLPGAP-----------------------GDQGQRGPPGEAGPKGDRGAE 522
             G  G+PGP G PG P                       G  G  GP G+ GP G+ GA 
Sbjct: 803  DGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAM 862

Query: 523  GARGIPGLPGPKGDTG------LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVP 576
            G  G+ G PG KGD G      + G+ G+ G PG PG  GEPG+ GP GD G  G  G  
Sbjct: 863  GLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPS 922

Query: 577  GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP 636
            G PG  G  G  G+ G  GKPG  G  G+ G QG PG+ G +G +G PG  G  G +G  
Sbjct: 923  GKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982

Query: 637  GLPGKLGSLGSPGLPGLPGPPGLPGMKGD------------------------------- 665
            G PG  GS+GSPG  G PG PG+PG+  D                               
Sbjct: 983  GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK 1042

Query: 666  -------RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPE- 717
                       G PGP G+ G  G  G+ G +G  G  G  G  G  G PG PGL G   
Sbjct: 1043 LPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSA 1101

Query: 718  -GSRGLPGVEGPRGPPGPRG 736
             G  G PG  GP+GPPGP G
Sbjct: 1102 LGLPGSPGAPGPQGPPGPSG 1121



 Score =  340 bits (873), Expect = 3e-93
 Identities = 216/548 (39%), Positives = 258/548 (47%), Gaps = 83/548 (15%)

Query: 431 HKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 490
           +KG  G  G PG  G KG +G+ GE G  GA G PG +G +G  G  G+ GEKG +G  G
Sbjct: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349

Query: 491 EPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPG 550
           +P   GL G  G +G  GP G  GPKG++G  G  G P LPG  G  G  G  G++G  G
Sbjct: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409

Query: 551 MPGTKGEPGKPGPPGDAGLQGLPGVPGIPG--------------AKGVAGEKGSTGAPGK 596
             G  G PGKPGPPG  G  G+ G+    G              A G+ G+KG TG PG 
Sbjct: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469

Query: 597 PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 656
           PG +G  G+ G+ G P   G +G +G PG  G  G  G PG PG  G +GSPGL G  G 
Sbjct: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529

Query: 657 PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL-GDIGLPGPKGSAG--------- 706
            G  G +G  G VG PG  G  G  G +GE G+ G + G  GLPGPKG AG         
Sbjct: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589

Query: 707 -----NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV-----QGEQGATGLPGVQGPPGRA 756
                NPG PG RGP+G RGLPGV G  G  GP+G+      G QG  G PG+QGP G  
Sbjct: 590 PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG-- 647

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN--------- 807
                               +  +   P  G  G+PGR G PG PGPPG+          
Sbjct: 648 -----------------LPGLPGTPGTP--GNDGVPGRDGKPGLPGPPGDPIALPLLGDI 688

Query: 808 -------------GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGL 853
                          PG    +G  G  G PG       KGD+G +G  G PGR GP G 
Sbjct: 689 GALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGS 748

Query: 854 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
            G  G PG PG       G +G +G PG+ G PG  GPPG  G  G   P     + G  
Sbjct: 749 KGERGYPGIPG-----EKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSD 803

Query: 914 AFNKGPDP 921
                P P
Sbjct: 804 GPPGKPGP 811



 Score =  289 bits (740), Expect = 7e-78
 Identities = 182/436 (41%), Positives = 209/436 (47%), Gaps = 74/436 (16%)

Query: 266  DERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 325
            D     G+ GP GPPG PG  G  G  G+RG  G PG  G  G  G PG PG PG  G  
Sbjct: 723  DSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPP 782

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA-----GLPGELGRVGP 380
            GL G  G PG  G+KG+KG  G PG         PGPPGPPG       G+       G 
Sbjct: 783  GLMGRTGHPGPTGAKGEKGSDGPPGK--------PGPPGPPGIPFNERNGMSSLYKIKGG 834

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
            V  P   GPPGPPGP G  G +G             PG  G PGL G  G KG +G  G 
Sbjct: 835  VNVPSYPGPPGPPGPKGDPGPVG------------EPGAMGLPGLEGFPGVKGDRGPAGP 882

Query: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 500
            PG  G  G+ G  G  G  G  G  G  G  G  G  G  G+ G  G DG PG QG+ G 
Sbjct: 883  PGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGK 942

Query: 501  PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 560
            PGD+G +G  G+ G  GDRG++G RG PGL      TG+ G  G  G PG  G+ G PG 
Sbjct: 943  PGDRGPKGERGDQGIPGDRGSQGERGKPGL------TGMKGAIGPMGPPGNKGSMGSPGH 996

Query: 561  PGPPGDAGLQGLPGVPGIPGAKGVAGEK------------------------------GS 590
             GPPG       PG+PGIP A  V+ E+                               +
Sbjct: 997  QGPPGS------PGIPGIP-ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLA 1049

Query: 591  TGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE--LGPVGSPGLPGKLGSLGSP 648
              A G+PG  G  G P   GPPG+ GP+G +G  G RGE  +G  GSPGLPG   +LG P
Sbjct: 1050 AQAYGRPGPPGKDGLP---GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPG-TSALGLP 1105

Query: 649  GLPGLPGPPGLPGMKG 664
            G PG PGP G PG  G
Sbjct: 1106 GSPGAPGPQGPPGPSG 1121



 Score =  244 bits (622), Expect = 3e-64
 Identities = 164/418 (39%), Positives = 180/418 (43%), Gaps = 66/418 (15%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P       GP G +G  G PG PG  G +G+ G  G  G PGP GP G  G+ G PG  G
Sbjct: 736  PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795

Query: 321  TPGADGLTGPDGSPGSIGSKG--------------QKGEPGVPGSRGFPGRGIPGPPGPP 366
              G  G  GP G PG  G  G               KG   VP   G PG   PGP G P
Sbjct: 796  AKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGP--PGPKGDP 853

Query: 367  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426
            G  G PG +G  G  G PG +G  GP GPPG  G  G             PG  G PG+P
Sbjct: 854  GPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG------------KPGAPGPPGVP 901

Query: 427  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 486
            G  G +G  G+IG PG +G  G+ G  G+ G  GAQG  G  G RG  G  GD+G  G R
Sbjct: 902  GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961

Query: 487  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDT--------- 537
            G  GE G  GL G  G  G  GPPG  G  G  G +G  G PG+PG   D          
Sbjct: 962  GSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKY 1021

Query: 538  --------------------GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
                                 LP         G PG  G+ G PGPPGD      PG  G
Sbjct: 1022 INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD------PGPQG 1075

Query: 578  IPGAKGVAGEKGSTGAPGKPGQMGNS--GKPGQQGPPGEVGPRGPQGLPGSRGELGPV 633
              G KG  GE G  G PG PG  G S  G PG  G PG  GP GP G       L PV
Sbjct: 1076 YRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPV 1132



 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 39/85 (45%), Positives = 46/85 (54%), Gaps = 7/85 (8%)

Query: 254  ELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP-----KGPPGPPGPA- 307
            +LPA +  +Q     GPPG+ G PGPPG PG  G  G  G+RG       G PG PG + 
Sbjct: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSA 1101

Query: 308  -GEPGKPGAPGKPGTPGADGLTGPD 331
             G PG PGAPG  G PG  G   P+
Sbjct: 1102 LGLPGSPGAPGPQGPPGPSGRCNPE 1126


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  541 bits (1394), Expect = e-153
 Identities = 324/743 (43%), Positives = 363/743 (48%), Gaps = 79/743 (10%)

Query: 247 PRRETCHELP---ARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP 303
           P  E C   P      T  +TT   GP G+ GP GP GP G PG DGI G  G  GPPGP
Sbjct: 87  PEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGP 146

Query: 304 PGPAGEPGKPG-------------------APGKPGTPGADGLTGPDGSPGSIGSKGQKG 344
           PGP G PG  G                    PG  G  G  GL GP G+PG  G +G  G
Sbjct: 147 PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPG 206

Query: 345 EPGVPGSRGFPG-RGIPGPP---GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRG 400
           EPG PG+ G  G RG PGPP   G  G AG PG  G  GP G  G RG PG  G PG +G
Sbjct: 207 EPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKG 266

Query: 401 TIGFHDGDPLCPNACPPGRSGYP------GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQG 454
             GF   D    +A P G  G P      G PG  G +G  GE G PG  G  G  G+ G
Sbjct: 267 HRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG 326

Query: 455 ELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGL---PGAPGDQGQRGPPG 511
             G  G  GP G  G  G  G VG KGE G +G  G  GPQG+   PG PG  G  GP G
Sbjct: 327 ATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG 386

Query: 512 EAGPKGDRGAEGARGIPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPG 559
             G  G  GA+GA G PG+             GP+G  G PG  G  G PG PG+KG+ G
Sbjct: 387 NPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446

Query: 560 KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 619
             G PG  G+QG PG  G  G +G  GE G TG PG PG+ G  G  G  G  G  GP+G
Sbjct: 447 AKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG 506

Query: 620 PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQG 679
           P G  GS G  GP GSPG  G+ G  G PG  GL G PG PG  G     G PGP G+ G
Sbjct: 507 PAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK---TGPPGPAGQDG 563

Query: 680 ASGEEGEAGERGELGDIGLPGPKGSAGNPGE---------PGLRGPEGSRGLPGVEGPRG 730
             G  G  G RG+ G +G PGPKG+AG PG+         PG  GP G  G  G +GP G
Sbjct: 564 RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623

Query: 731 PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 790
           P GP G +GEQG  G PG QG PG A       +   + +         S  R + G  G
Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683

Query: 791 LPGRPGPPGPPGPPGENGFPGQMGIR------------GLPGIKGPP---GALGLRGPKG 835
             G  GPPGP GP G NG PG  G +            G PG++G P   GA GL GPKG
Sbjct: 684 ERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKG 743

Query: 836 DLGE---KGERGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPG 890
           D G+   KG  G PG+ G  GL G IG PG  G P   G +G  G  GP G  G PG  G
Sbjct: 744 DRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG 803

Query: 891 PPGPPGLPGFCEPASCTMQAGQR 913
            PGPPG  GF  P     Q G +
Sbjct: 804 EPGPPGPAGFAGPPGADGQPGAK 826



 Score =  540 bits (1392), Expect = e-153
 Identities = 333/774 (43%), Positives = 383/774 (49%), Gaps = 130/774 (16%)

Query: 255 LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPP------GPAG 308
           +P  + PS      GPPG  GP G  GPPG PG  G  G  GP+GPPGPP      G AG
Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG 236

Query: 309 EPGKPGAPGKPGTPGADGL---------------TGPDGSPGSIGSKGQKGEPGVPGSRG 353
           +PG+PG  G PG  GA GL               +G DG+ G  G  G KGEPG PG  G
Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 296

Query: 354 FPG----RGIP------------------------GPPGPPGTAGLPGELGRVGPVGDPG 385
            PG    RG+P                        GPPGP G AG PG  G VG  G+ G
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG 356

Query: 386 RRGP---------PGPPGPPGPRGTIG-----FHDGDPLCPNA-CPPGRSGYPGLPGMRG 430
            +GP          G PGPPGP G  G       DG P    A   PG +G PG PG RG
Sbjct: 357 PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416

Query: 431 HKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 490
             G +G  G PG +G+ GE G  G  G+ GA+G PG  G++G  G  G++G++GAR   G
Sbjct: 417 PSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR---G 473

Query: 491 EPGPQGLPGAPGDQ---------------------GQRGPPGEAGPKGDRGAEGARGIPG 529
           EPGP GLPG PG++                     G+RG PG AGPKG  G  G  G  G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533

Query: 530 LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 589
           LPG KG TG PG  G DG  G PG  G+ G+PGPPG  G +G  GV G PG KG AGE G
Sbjct: 534 LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPG 593

Query: 590 ST---GAPGKPGQMGNSGKPGQ---QGPPGEVGP------RGPQGLPGSRGELGPVGSPG 637
                G PG PG +G +GK G+   QGPPG  GP      +GP G PG +G  GP G PG
Sbjct: 594 KAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPG 653

Query: 638 LPGKLGSLGSPGLPGLPGPPGLPGMK---GDRGVVGEPGPKGEQGASGEEGEAGERGELG 694
             GK G  G PG  G PGP G  G +   G+RGV G PGP G +GA+G  G  G +   G
Sbjct: 654 EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAK---G 710

Query: 695 DIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGP-- 752
           D G PG  GS G PG  G+ G  G+ GLPG +G RG  GP+G  G  G  G+ G+ GP  
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG 770

Query: 753 ---PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
              P  AP D+                   S     +G TG  G PG  G PGPPG  GF
Sbjct: 771 PPGPAGAPGDK-----------------GESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813

Query: 810 PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-PAS 867
            G  G  G PG KG PG  G +G  G  G  G  GPPG  G  G PGA G  G  G P +
Sbjct: 814 AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA 873

Query: 868 YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
            G  G  G  GPPG +G  G PGPPGP G  G   P   T  AG+      P P
Sbjct: 874 TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927



 Score =  540 bits (1391), Expect = e-153
 Identities = 316/686 (46%), Positives = 354/686 (51%), Gaps = 80/686 (11%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    P   T   GP G+ G PGPPGPPG  G  G+ G  GPKG  G PG AGE G PG 
Sbjct: 544  PGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGP 603

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375
            PG  G  G DG  G  G PG  G  G++GE G  GS GF  +G+PGP GPPG AG PGE 
Sbjct: 604  PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF--QGLPGPAGPPGEAGKPGEQ 661

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G  G +G PG  G  G  G PG RG  G            PPG +G  G  G  G+ GAK
Sbjct: 662  GVPGDLGAPGPSGARGERGFPGERGVQG------------PPGPAGPRGANGAPGNDGAK 709

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITG---IVGDKGEKGARGLDGEP 492
            G+ G PG  G +G  G QG  GE GA G PG +G RG  G     G  G+ G RGL G  
Sbjct: 710  GDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI 769

Query: 493  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552
            GP G  GAPGD+G+ GP G AGP G RGA G RG PG PGP G  G PG DG+ G  G P
Sbjct: 770  GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP 829

Query: 553  GTKGEPGKPGPPGDAGLQGLPG------VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 606
            G  G  G  GPPG AG  G PG       PG  GA+G AG  G+TG PG  G++G  G  
Sbjct: 830  GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889

Query: 607  GQQGPPGEVGPRGPQGLPGSRGELGP------VGSPGLPGKLGSLGSPGL------PGLP 654
            G  GPPG  GP G +G  G RGE GP      VG PG PG  G  GSPG       PG P
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 655  GPPG---------LPGMKGDRGVVGEPGPKGE---QGASGEEGEAGERGELGDIGLPGPK 702
            GP G         LPG +G+RG  G PGP GE   QG SG  GE G  G +G  GL GP 
Sbjct: 950  GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPP 1009

Query: 703  GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 762
            G +G  G PG  G  G  G PG +G RG  GP G  G  GA G PG  GP G++      
Sbjct: 1010 GESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS------ 1063

Query: 763  KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 822
                         +   +     +G  G  G  GP GP GP G+ G  G+ G RG+ G +
Sbjct: 1064 ------------GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111

Query: 823  G---------PPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASY-GRNG 872
            G         PPG+ G +GP G  G  G RGPPG    G PG  GL G PGP    G  G
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLPGPIGPPGPRG 1169

Query: 873  RDGERGPPGVAGIPGVPGPPGPPGLP 898
            R G+ GP    G PG PGPPGPPG P
Sbjct: 1170 RTGDAGP---VGPPGPPGPPGPPGPP 1192



 Score =  526 bits (1355), Expect = e-149
 Identities = 312/712 (43%), Positives = 352/712 (49%), Gaps = 91/712 (12%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPG---------VPGIDGIDGDRGP---KGPPGPPGPAG 308
            P+    +RG  GE GP G PGPPG          PG DG+ G +GP   +G PGP GP G
Sbjct: 462  PAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKG 521

Query: 309  EPGKPGAPGKPGTPGADGLTGPDGSPGS---------IGSKGQKGEPGVPGSRG------ 353
             PG+ G PG+ G PGA GLTG  GSPG           G  G+ G PG PG+RG      
Sbjct: 522  SPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMG 581

Query: 354  FPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP 412
            FPG +G  G PG  G  G+PG  G VGP G  G  G  GPPGP GP G  G        P
Sbjct: 582  FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG-----P 636

Query: 413  NACP-----PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGA 467
               P     PG +G PG  G  G +G  G++G PG  G +GE G  GE G    QGPPG 
Sbjct: 637  AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERG---VQGPPGP 693

Query: 468  QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI 527
             G RG  G  G+ G KG  G  G PG QG PG  G  G+RG  G  GPKGDRG  G +G 
Sbjct: 694  AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753

Query: 528  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKGV 584
             G PG  G  GL G  G  G  G PG KGE G  GP G  G +G PG    PG PG  G 
Sbjct: 754  DGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF 813

Query: 585  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG---------LPGSRGELGPVGS 635
            AG  G+ G PG  G+ G++G  G  GPPG  GP GP G           G+RG  GP G+
Sbjct: 814  AGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA 873

Query: 636  PGLPGKLGSLGSPGLPGLPGPPGLPGM------KGDRGVVG------EPGPKGEQGASGE 683
             G PG  G +G PG  G  GPPG PG       KG RG  G      E GP G  G +GE
Sbjct: 874  TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGE 933

Query: 684  EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGA 743
            +G  G  G  G  G PGP+G AG  G  GL G  G RG PG+ GP G PG +G  G  G 
Sbjct: 934  KGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993

Query: 744  TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP 803
             G PG  GPPG A                            +SG  G PG  G PG  G 
Sbjct: 994  RGPPGPMGPPGLAGPPG------------------------ESGREGAPGAEGSPGRDGS 1029

Query: 804  PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGD 862
            PG  G  G+ G  G PG  G PGA G  GP G  G++GE GP G  GP G  GA G  G 
Sbjct: 1030 PGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP 1089

Query: 863  PGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
             GP    G  G  G+RG  G  G  G+ GPPGPPG PG   P+  +  AG R
Sbjct: 1090 QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141



 Score =  416 bits (1068), Expect = e-116
 Identities = 246/556 (44%), Positives = 271/556 (48%), Gaps = 82/556 (14%)

Query: 261  PSQTTDERGPPGEQGPPGP---PGPPGVPGIDGIDGDRGPKGPPGPPGPAG--------- 308
            P+    E G PGEQG PG    PGP G  G  G  G+RG +GPPGP GP G         
Sbjct: 648  PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDG 707

Query: 309  ---EPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPG 361
               + G PGAPG  G PG  G+ G  G+ G  G KG +G+ G  G+ G PG    RG+ G
Sbjct: 708  AKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG 767

Query: 362  PPGPPGTAGLPG---ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPG 418
            P GPPG AG PG   E G  GP G  G RG PG  G PGP G  GF         A PPG
Sbjct: 768  PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF---------AGPPG 818

Query: 419  RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG------PPGAQGLRG 472
              G PG  G  G  GAKG+ G PG  G  G  G  G +G  GA+G      PPGA G  G
Sbjct: 819  ADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPG 878

Query: 473  ITGIVGDKGEKGARGLDGEPGPQGLPGA------------PGDQGQRGPPGEAGPKGDRG 520
              G VG  G  G  G  G PGP G  G             PG+ G  GPPG AG KG  G
Sbjct: 879  AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938

Query: 521  AEGARGIPGLPGP------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG 574
            A+G  G PG PGP      +G  GLPG  G  G PG+PG  GEPGK GP G +G +G PG
Sbjct: 939  ADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998

Query: 575  VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS-------- 626
              G PG  G  GE G  GAPG  G  G  G PG +G  GE GP GP G PG+        
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058

Query: 627  -------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE-------- 671
                   RGE GP G  G  G +G+ G  G  G  G  G  G +GDRG+ G         
Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQG 1118

Query: 672  ----PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 727
                PG  GEQG SG  G AG RG  G  G PG  G  G PG  G  GP G  G  G  G
Sbjct: 1119 PPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVG 1178

Query: 728  PRGPPGPRGVQGEQGA 743
            P GPPGP G  G   A
Sbjct: 1179 PPGPPGPPGPPGPPSA 1194



 Score =  359 bits (922), Expect = 6e-99
 Identities = 210/486 (43%), Positives = 233/486 (47%), Gaps = 50/486 (10%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 306
            P ++    L   I P       G  GE GP GP GP G  G  G  G+ GP GP G  GP
Sbjct: 757  PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP 816

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366
             G  G+PGA G+PG  GA G  GP G  G  G  G  G  G PG+     +G  G  GPP
Sbjct: 817  PGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGA-----KGARGSAGPP 871

Query: 367  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426
            G  G PG  GRVGP G  G  GPPGPPGP G  G  G            P G +G  G P
Sbjct: 872  GATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG------------PRGETGPAGRP 919

Query: 427  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 486
                     GE+G PG  G  GE+G  G  G  GA G PG QG+ G  G+VG  G++G R
Sbjct: 920  ---------GEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGER 970

Query: 487  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
            G  G PGP    G PG QG  G  GE GP G  G  G  G PG  G +G  G  G  GRD
Sbjct: 971  GFPGLPGPS---GEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD 1027

Query: 547  GIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 606
            G PG  G +GE G  GPP      G PG PG PG  G AG+ G  G  G  G  G  G  
Sbjct: 1028 GSPGAKGDRGETGPAGPP------GAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPV 1081

Query: 607  GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 666
            G +GP G  GPRG +G  G +G+ G  G  G  G  G  G PG PG  GP G  G  G R
Sbjct: 1082 GARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141

Query: 667  GVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 726
                  GP G  GA G++G           GLPGP G  G  G  G  GP G  G PG  
Sbjct: 1142 ------GPPGSAGAPGKDGLN---------GLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 727  GPRGPP 732
            GP GPP
Sbjct: 1187 GPPGPP 1192



 Score =  197 bits (502), Expect = 3e-50
 Identities = 130/328 (39%), Positives = 142/328 (43%), Gaps = 77/328 (23%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKG------PPGPPGPAGEPGKPGAPGK---P 319
            GP G  GPPGPPGP G  G  G  G+ GP G      PPGPPGPAGE G PGA G    P
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 320  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTA 369
            GTPG  G+ G  G  G  G +G++G PG+PG  G PG          RG PGP GPPG A
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 370  GLPGELGR------------------------VGPVGDPGRRGPPGPPGPPGPRGTIGFH 405
            G PGE GR                         GP G PG  G PG PGP GP G  G  
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE------------------PGRQGHK 447
                    A P G  G  G  G +G +G KGE GE                  PG  G  
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 448  GEEGDQGELGEVGAQGPPGAQGLRGITGI---------------VGDKGEKGARGLDGEP 492
            GE+G  G  G  G +GPPG+ G  G  G+                GD G  G  G  G P
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 493  GPQGLPGAPGD-QGQRGPPGEAGPKGDR 519
            GP G P A  D      PP E    G R
Sbjct: 1187 GPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 47/125 (37%), Positives = 52/125 (41%), Gaps = 41/125 (32%)

Query: 816 RGLPGIKGPPG-----------------ALGLRGPKGDLGEKGER---GPPGR----GPN 851
           +  PG + P G                   G+ GPKGD G +G R   GPPGR    G  
Sbjct: 79  KNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP 138

Query: 852 GLPGAIGLPGDPGPASYGRN-------GRD----------GERGPPGVAGIPGVPGPPGP 894
           GLPG  G PG PGP   G N       G D          G  GP G  G+PG PG PGP
Sbjct: 139 GLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGP 198

Query: 895 PGLPG 899
            G  G
Sbjct: 199 QGFQG 203


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score =  541 bits (1393), Expect = e-153
 Identities = 361/952 (37%), Positives = 447/952 (46%), Gaps = 150/952 (15%)

Query: 74  IQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQI 133
           ++R  G     VAY++        PTR L+P G P+++S LT  R           ++  
Sbjct: 47  VRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSA 106

Query: 134 QDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAA---FSNLSSLFDSQWHKIMIGVERS 190
           Q   G  Q+G+++    + V F Y+   G  Q  +   F  L SL D +WH++ + V+  
Sbjct: 107 Q---GVRQLGLELG---RPVRFLYEDQTGRPQPPSQPVFRGL-SLADGKWHRVAVAVKGQ 159

Query: 191 SATLFVDCNR--IESLPIKPRGPIDIDGFAVLG--------------KLADNPQVSVPFE 234
           S TL VDC +     LP   R  +D  G  + G              +LA  P V   +E
Sbjct: 160 SVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYE 219

Query: 235 -LQWMLIHCD---PLRPRRETCH-------ELPARI-------------TPSQTTD---- 266
             +   + C+     RP+ +  H       + P+R+             TP +  +    
Sbjct: 220 SCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILES 279

Query: 267 ------------------ERGPPG-------EQGPPGPPGPPGVPGIDGIDGDRGPKGPP 301
                             E+G P         +GPPGP GP G+ G  GI G+ GP G P
Sbjct: 280 SLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDP 339

Query: 302 ---GPPGPAGEPGKPGAPGKPGT----PGADGLTGPDGSP---------GSIGSKGQKGE 345
              GPPG AG PG  GAPG PGT    P   G  G D  P          +I  + +   
Sbjct: 340 GERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLAL 399

Query: 346 PGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH 405
            G PG  G+ GR  PGP G PG+ GL GE G +GP G  G +G  GPPG  G RG  G  
Sbjct: 400 RGPPGPMGYTGR--PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 457

Query: 406 -----DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE-- 458
                 GDP        G  G PGLPG +GH+G  G  G PG  G  GE GD GE+G   
Sbjct: 458 GARGMPGDPGVKG--DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 515

Query: 459 ----------VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRG 508
                     +G +GPPG  G  G+ G+ G +G KG+ G  GEPGP G  G PG QG  G
Sbjct: 516 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575

Query: 509 PPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
           P G  GP G++G +G  G+PG+PG  G    PG  G++G PG  G +G  G  GP G  G
Sbjct: 576 PQGAIGPHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPG 632

Query: 569 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
            +G+ GV GI G KG  GEKG  G PG  G +G  G  G+ G PG  G  GP+   G +G
Sbjct: 633 PRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE---GPKG 689

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
             GP G PG PG +G  G  G+PGLPG PG  G KG  G  G PG  GE+GA G  G++G
Sbjct: 690 RTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSG 749

Query: 689 ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG 748
            RGE       GP G  G  G  G  G  G++G  G +GP GPPG RG+ G QG  G PG
Sbjct: 750 PRGE------RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPG 803

Query: 749 VQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD-------SGATGLPGRPGPPGPP 801
            +GPPG    D        R  +  F         P        +G TG  G  G PGPP
Sbjct: 804 PKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 862

Query: 802 GPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG----------RGPN 851
           GPPGE G PG  G  G  G  GPPGA G  GP G  G  GERG PG           GP+
Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 922

Query: 852 GLPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
           G PG  G PG+ G A      G  GR G +GPPG AG  GVPG  GP G  G
Sbjct: 923 GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 974



 Score =  517 bits (1331), Expect = e-146
 Identities = 310/701 (44%), Positives = 360/701 (51%), Gaps = 100/701 (14%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            E GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G
Sbjct: 558  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 617

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPG 373
              GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG
Sbjct: 618  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPG 677

Query: 374  ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMR 429
              G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  
Sbjct: 678  SRGEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGAS 736

Query: 430  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIV 477
            G KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  
Sbjct: 737  GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQ 796

Query: 478  GDKGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGAR 525
            G  G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G R
Sbjct: 797  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 856

Query: 526  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAK 582
            G PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG K
Sbjct: 857  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 916

Query: 583  GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 642
            G  G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ 
Sbjct: 917  GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 976

Query: 643  GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
            G  G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   
Sbjct: 977  GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP--- 1033

Query: 703  GSAGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPP 753
            G+AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPP
Sbjct: 1034 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1093

Query: 754  G----RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
            G    R P                            +GA G  G PG  G  GPPGE G 
Sbjct: 1094 GPPGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 810  PGQM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGL 859
            PG+    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G 
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1185

Query: 860  PGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            PGDPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1186 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1226



 Score =  506 bits (1303), Expect = e-143
 Identities = 299/686 (43%), Positives = 343/686 (50%), Gaps = 65/686 (9%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P   T + G  G  G  GP GPPG  G+ G  G  G  GP GPPGP G+ G PG PG+ G
Sbjct: 765  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 824

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
              G  G TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G 
Sbjct: 825  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGT 879

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
             GDPG   PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G 
Sbjct: 880  KGDPG---PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGS 930

Query: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGL 497
            PG +G  G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G 
Sbjct: 931  PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 990

Query: 498  PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557
            PG  G+ G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G 
Sbjct: 991  PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1050

Query: 558  PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617
             G  G  G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G 
Sbjct: 1051 FGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGA 1107

Query: 618  RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGE 677
             GPQG PG  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G 
Sbjct: 1108 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1167

Query: 678  QGASGEEGEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGL 722
            +G +G++G  G  G +G  G PGP               +G  G PG+PG  GP G  G 
Sbjct: 1168 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1227

Query: 723  PGVEGPRGP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFA 775
            PG  G RGP   PG  G QG +GA G PG  G PG+     P     K        +   
Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLR 1282

Query: 776  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 835
             +  S+     G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G
Sbjct: 1283 GLPGSV-----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337

Query: 836  DLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895
            + GEKG+RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP 
Sbjct: 1338 EQGEKGDRGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPK 1384

Query: 896  GLPGFCEPASCTMQAGQRAFNKGPDP 921
            G  G   P     + G +     P P
Sbjct: 1385 GAKGATGPGGPKGEKGVQGPPGHPGP 1410



 Score =  486 bits (1251), Expect = e-137
 Identities = 290/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 323
            +RG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 822  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 881

Query: 324  ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 379
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 434
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999

Query: 435  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 494
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1059

Query: 495  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 554
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119

Query: 555  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 671
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 672  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 728
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1299

Query: 729  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1300 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1342

Query: 777  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 831
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1390

Query: 832  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 889
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1391 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1448

Query: 890  GPPG 893
            G PG
Sbjct: 1449 GSPG 1452



 Score =  424 bits (1089), Expect = e-118
 Identities = 255/595 (42%), Positives = 296/595 (49%), Gaps = 62/595 (10%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAG 308
            LP       T  + GPPG  G  GP      PG  G+PG  G  G +G +GP GPPGPAG
Sbjct: 870  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 929

Query: 309  EPGK------------PGAPGKPGTPGAD------------------------GLTGPDG 332
             PG+            PG PG  G PGA                         GL GP G
Sbjct: 930  SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 989

Query: 333  SPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPG 391
             PG  G  G KGE G PG +G  G +G  GPPGPPG  G  G+ G  G  G+PG RGP G
Sbjct: 990  PPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1049

Query: 392  PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 451
              G  G  GT GF+          PPG  G  GLPG  G KG  G++G  G  G  G  G
Sbjct: 1050 HFGAKGDEGTRGFNG---------PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1100

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---GPQGLPGAPGDQGQRG 508
              G  G  G QGPPG  G  G  G  G+ GE G+ G+ GEP   GP+G  G  G+ GQ G
Sbjct: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1160

Query: 509  PPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
             PG  GPKG  G +G +G PG  G  GD G PG  G  G  G  G +GE G+PG PG  G
Sbjct: 1161 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1220

Query: 569  LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
              G  G PG  G +G AG  GS G  G  G  G+ G  G  G  G VGP GP G PG  G
Sbjct: 1221 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1280

Query: 629  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              G  GS G  G+ G+ G  G PG  GPPGLPG++GD G  GE   KG  G  G  G  G
Sbjct: 1281 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPG 1337

Query: 689  ERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745
            E+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP GP G +G  G  G  G
Sbjct: 1338 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1397

Query: 746  LPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
              GVQGPPG   P  + I+ + +++ ++    +  S    +  A    G PG PG
Sbjct: 1398 EKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1452


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  537 bits (1384), Expect = e-152
 Identities = 332/754 (44%), Positives = 383/754 (50%), Gaps = 138/754 (18%)

Query: 255 LPARITPSQTTDERGPPGEQG---PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPG 311
           +P  + P      +G  G+QG   P GPPG PG PG  G  G RGP+GPPG PG  GEPG
Sbjct: 211 MPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG 270

Query: 312 K---------PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPG 361
           +          G+PG  G PGA GL G  G  G  G +G KGE G PGS+G  G  G  G
Sbjct: 271 RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG 330

Query: 362 PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD--------------- 406
             GP G  G+PGE GR+GP G PG+RG  G PG PGP G +G                  
Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390

Query: 407 -----------------------GDPLCPNAC-------------------PPGRSGYPG 424
                                  G P  P A                    PPG +G PG
Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 425 LPGMRGH---KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP---PGAQGLRG------ 472
            PG +G    +G +G+ G+PG  G KGE G +GE G  G QGP   PG +G RG      
Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510

Query: 473 ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532
             G  G  GE+GA G  G PG  GLPG  G QG+RGP G +GPKG +G  G  G PGLPG
Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570

Query: 533 PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTG 592
            +G TG PGV G +G  G  G  GE G+PGPPG  G++G PG  G+PG KG      S+G
Sbjct: 571 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG------SSG 624

Query: 593 APGKPGQMGNSGKPGQQGPPG---EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            PGKPG+ GN+G PGQ+G PG   EVGP GP G PG  GE G  G PG        G  G
Sbjct: 625 DPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG------PTGFQG 678

Query: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
           LPG PGPPG  G  GD+GV G+PG  G  G  GE G  GERGE G  GLPG KG AG  G
Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHG 738

Query: 710 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
             G   P+GS G  G  G  GPPG +G+ GE+G  G PG +G  G               
Sbjct: 739 PDG---PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG-------------- 781

Query: 770 IQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG------ 823
           I E  AE  A     + GA GLPG  GPPGP GP GE G PG  G+ G PG +G      
Sbjct: 782 IGEKGAEGTAG----NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRG 837

Query: 824 ---PPGALGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGPASY----GRNG 872
              P GA+G  GP+G  G+ G +G PG    +G  G PG  GL G PGP       G  G
Sbjct: 838 ENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG 897

Query: 873 RDGERGPPGVAGIPGVP---GPPGPPGLPGFCEP 903
             G +GPPG  G PG     GPPGP G PG   P
Sbjct: 898 GRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931



 Score =  527 bits (1358), Expect = e-149
 Identities = 339/791 (42%), Positives = 386/791 (48%), Gaps = 120/791 (15%)

Query: 234 ELQWMLIHCDPLRPRRETCHELPARITPSQTTDERGPPGEQGPPG----------PPGPP 283
           E Q +L   DP+ P  E C           T   RG  G++G PG           PGP 
Sbjct: 75  ECQDVLDCADPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPA 134

Query: 284 GVPGIDGIDGDRGPKGPPGPPGPA---GEPGKPGAPGKPGTPGADGLTGPDG-------- 332
           G PG  G  G+RGPKG PGP GP    GEPG PG PG PG PG     GPDG        
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194

Query: 333 ----------------SPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG 376
                            PGS+G  G +G  G+ G +G  G G  GPPG PG  G  G +G
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQG--GAGPTGPPGEPGDPGPMGPIG 252

Query: 377 RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 436
             GP G PG+ G  G PG  G  G +GF  G P       PG  G PGL G RGHKG +G
Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGF-AGSPGARGF--PGAPGLPGLKGHRGHKGLEG 309

Query: 437 EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ- 495
             GE G  G KGE G  G +G +G  GP G  G RG  G  G  G++GA G+ G+PGP  
Sbjct: 310 PKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG 369

Query: 496 --GLPGAPGDQGQRGPPGEAGPKGDRGAE---GARGIPGLPGPKGDTGLPGVDGRDGIPG 550
             G+PG+ G  G  G  GEAGP G RG E   G RG  G PGP G  GLPG  G DG PG
Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429

Query: 551 MPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ- 609
             G  G PG  GPPG AG  G PG  G  G +G+ G+ G  G PG  G+ G  G+PG   
Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG 489

Query: 610 -----GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL----------- 653
                GPPGE G RGP+G PG+ G  GPVG  G PG  G  GS GLPG            
Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549

Query: 654 ----------PGPPGLPGMKGDRGVVGEPGPKGEQ------GASGEEGEAGE------RG 691
                     PG PG PG+ G RG+ G PG +G +      GA GE+G  G       RG
Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG 609

Query: 692 ELGDIGLPGPKGSAGNPGEP---GLRGPEGSRGLPGVE------GPRGPPGPRGVQGEQG 742
           + G +GLPGPKGS+G+PG+P   G  G  G RG PG +      GP GPPG  G +GEQG
Sbjct: 610 QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG 669

Query: 743 A------TGLPGVQGPPGRA--PTDQHIKQVCMRV-IQEHFAEMAASLKRPDSGATGLPG 793
                   GLPG  GPPG    P DQ +      V       E     +R + G TGLPG
Sbjct: 670 PPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPG 729

Query: 794 RP------GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD---LGEKGERG 844
                   GP GP G PG +G PG  G  GL G+ G  G  G  GPKGD   +GEKG  G
Sbjct: 730 EKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEG 789

Query: 845 PPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGER---GPPGVAGIPGVPGPPGPPGLPGF 900
             G  G  GLPG +G PG  GP   G  G  G R   GPPG  G PG  G  GP G  GF
Sbjct: 790 TAGNDGARGLPGPLGPPGPAGPT--GEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGF 847

Query: 901 CEPASCTMQAG 911
             P     Q G
Sbjct: 848 AGPQGPDGQPG 858



 Score =  524 bits (1349), Expect = e-148
 Identities = 313/697 (44%), Positives = 350/697 (50%), Gaps = 52/697 (7%)

Query: 255  LPARITPSQTTDERGP---PGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG------ 305
            LP  I    T   +GP   PG  GPPG  GPPG PG  G  G +G +G PG PG      
Sbjct: 418  LPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKG 477

Query: 306  ---PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPG 361
               P GEPG  G  G  G PG +G  GP G PG++G  G  GE G PG+RGFPG  G+PG
Sbjct: 478  EAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG 537

Query: 362  PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGP---------PGPRGTIG-----FHDG 407
            P G  G  G  G  G  G  GDPGR G PG PG           GP G +G       DG
Sbjct: 538  PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDG 597

Query: 408  DPLCPNACP-PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466
             P  P +    G+ G  GLPG +G  G  G+ GE G  G  G+ G  G+ GEVG  GP G
Sbjct: 598  RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVG 657

Query: 467  AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP---KGDRGAEG 523
              GL G  G  G  G  G +GL G PGP G  G PGDQG  G PG  GP   +G+RG  G
Sbjct: 658  PPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPG 717

Query: 524  ARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKG 583
             RG PG+ G  G+ G+ G  G DG  G PG  G PG  GPPG  G+ G  G+ G PG KG
Sbjct: 718  ERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKG 777

Query: 584  VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLG 643
              G  G  GA G  G  G  G PG  GPPG  GP G +G PG RG +GP GS G PG  G
Sbjct: 778  DRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRG 837

Query: 644  SLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKG 703
              G  G  G  GP G  G  G +G  GEPG KG+ G+ G +G AG  G  G  G+PG KG
Sbjct: 838  ENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG 897

Query: 704  SAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIK 763
              G  G PG  G  GS G  G  GP G PGP G  GE G  G PG++G PG         
Sbjct: 898  GRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG------ 951

Query: 764  QVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG------FPGQMGIRG 817
                RV     A         D G  G  G+PGP GPPGP G  G       PGQ G RG
Sbjct: 952  ----RVGDRGPAGPPGG--PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERG 1005

Query: 818  LPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASY-GRNGRDGE 876
            +PG+ GP G  G  GP G  G+KG  GP G  P G  G +G PG  GPA   G  GRDG 
Sbjct: 1006 MPGLPGPAGTPGKVGPTGATGDKGPPGPVG--PPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063

Query: 877  RGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
             G  G  G PG  G PG  G PG   P      AGQR
Sbjct: 1064 VGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQR 1100



 Score =  518 bits (1333), Expect = e-146
 Identities = 328/759 (43%), Positives = 381/759 (50%), Gaps = 126/759 (16%)

Query: 258  RITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGD------------RGPKGPPG--- 302
            R+ P     +RG  G  G PGP GP G+PG  G  G+            RGP+GP G   
Sbjct: 346  RLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG 405

Query: 303  ---PPGPAGEPGKPGAPGKPGTPGADGLTG------------PDGSPGSIGS------KG 341
               PPGP G PG PGA G  GTPGA G TG            P GSPG  GS      +G
Sbjct: 406  ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465

Query: 342  QKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRG 400
            Q G+PGVPG +G  G +G PGP G  G  G PGE G+ GP GDPG  GPPGP G  G  G
Sbjct: 466  QPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 401  TIGFHDGDPL------------CPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 448
              GF   D L              ++ P G  G PG PG  G  GA+G  G PG QG +G
Sbjct: 526  NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEG 585

Query: 449  EEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR- 507
            + G  G  GE G  GPPG+ G+RG  G +G  G KG+ G  G+PG  G  G PG +G   
Sbjct: 586  KLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPG 645

Query: 508  -----------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKG 556
                       GPPG AG +G++G  G  G  GLPGP G  G  G  G  G+PG PG  G
Sbjct: 646  KDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVG 705

Query: 557  EPGKPGPPGDAGLQGLPGVPGIPGAKGVA---GEKGSTGAPGKPGQMGNSGKPGQQGPPG 613
              G  G  G+ G +G PG+ G+PG KG+A   G  G  G+PG  G  G++G PG QG PG
Sbjct: 706  PLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPG 765

Query: 614  E------VGPRGPQ------------GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 655
            E       GP+G +            G  G+RG  GP+G PG  G  G  G PG  GL G
Sbjct: 766  ERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVG 825

Query: 656  PPGLPGMKGDR------GVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
            PPG  G  G R      G VG  GP+G  G  G +GE GE G+ GD G PGP+G AG+PG
Sbjct: 826  PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG 885

Query: 710  E------PGLR------GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-RA 756
                   PGL+      GP G+ G PG  G  GPPGP G  G  G  G PG +GPPG R 
Sbjct: 886  PHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRG 945

Query: 757  PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN------GFP 810
                H      RV     A         D G  G  G+PGP GPPGP G        G P
Sbjct: 946  DPGSH-----GRVGDRGPAGPPGG--PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMP 998

Query: 811  GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA-SYG 869
            GQ G RG+PG+ GP G  G  GP G  G+KG  GP   GP G  G +G PG  GPA + G
Sbjct: 999  GQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV--GPPGSNGPVGEPGPEGPAGNDG 1056

Query: 870  RNGRD------GERGPPGVAGIP---GVPGPPGPPGLPG 899
              GRD      G+RG PG AG+P   G PG PGP G PG
Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG 1095



 Score =  512 bits (1319), Expect = e-145
 Identities = 316/755 (41%), Positives = 369/755 (48%), Gaps = 123/755 (16%)

Query: 253  HELPARITPSQTTDERGPPGEQGPPGPPGP------------PGVPGIDGIDGDRGPKGP 300
            H +   I P     +RGP G+ G  GPPGP            PG  G+ G  G +G +GP
Sbjct: 488  HGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP 547

Query: 301  PGPPGPAGEPGKPGAPGKPGTPGADGLT------GPDGSPGSIGSKGQKGEPGVPGSRGF 354
             G  GP G  G PG PG+PG PGA GLT      GP+G  G +G+ G+ G PG PGS G 
Sbjct: 548  VGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGI 607

Query: 355  PGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413
             G+ G  G PGP G++G PG+ G  G  G PG+RG PG  G  GP G +G          
Sbjct: 608  RGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGE 667

Query: 414  ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGI 473
              PPG +G+ GLP   G  G  GE G+PG QG  G+ G  G LG  G +G PG +G  GI
Sbjct: 668  QGPPGPTGFQGLP---GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGI 724

Query: 474  TGIVGDKGEKGARGLD---GEPGPQGLPGAPGDQGQRGPPGE------AGPKGDRGAEGA 524
            TG+ G+KG  G  G D   G PGP G PG  G  G +G PGE       GPKGDRG  G 
Sbjct: 725  TGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGE 784

Query: 525  RGIP---------GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV 575
            +G           GLPGP G  G  G  G  G PG  G  G PG  G PG  G  G  G 
Sbjct: 785  KGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGA 844

Query: 576  PGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGELGP 632
             G  G +G  G+ G  G PG+PGQ G++G PG QG  G  GP GP G+P   G RG  GP
Sbjct: 845  VGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGP 904

Query: 633  VGSPGLPGKLGSLGSPGLPGLP------------GPPGLPGMKGDRGVVGEPGPKGEQGA 680
             G+ G PG  G +G PG  G P            GPPGL G  G  G VG+ GP G  G 
Sbjct: 905  PGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG 964

Query: 681  SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP------------ 728
             G++G+ GE G+ G  G PGP G+ G  G  G+ G  G RG+PG+ GP            
Sbjct: 965  PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024

Query: 729  ---RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
               +GPPGP G  G  G  G PG +GP G   T      V  R              R D
Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG------------DRGD 1072

Query: 786  SGATGLPGRPGPPGPPGP---PGENGF------------PGQMGIRGLPGIKGPPGALGL 830
             G  GLPG  G PG PGP   PG+ G             PG+ G RGLPG +GP G  G 
Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGD 1132

Query: 831  RGPKGDLGEKGER---------GPPG----RGPNGLPGAIGLPGDPGP----ASYGRNGR 873
             G +GD G+KG R         GPPG    +G  G+PG  G  G PGP       G  G 
Sbjct: 1133 HGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGP 1192

Query: 874  DGERGPPGVAGI---------PGVPGPPGPPGLPG 899
             G  GPPGV G          PG PGPPGPPG PG
Sbjct: 1193 LGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  506 bits (1303), Expect = e-143
 Identities = 304/698 (43%), Positives = 349/698 (50%), Gaps = 83/698 (11%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT------P 322
            GP G QG PG PG PG+PG  G+ G+ G +GP G  GP G PG+ G PG PG+      P
Sbjct: 552  GPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP 611

Query: 323  GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPV 381
            G+ GL GP GS G  G  G+ G  GVPG RG PG+ G  GP GP G  GL GE G  GP 
Sbjct: 612  GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671

Query: 382  GDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 441
            G  G +G PGPPGPPG  G                PG  G PG PG  G  G +GE G P
Sbjct: 672  GPTGFQGLPGPPGPPGEGGK---------------PGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 442  GRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP 501
            G +G  G  G  GE G  G  GP G +G  G +G  GD G  G +G+   PG +G+ G P
Sbjct: 717  GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM---PGERGIAGTP 773

Query: 502  GDQGQRGPPGEAGPKGDRGAEGARGIPGL---PGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G +G RG  GE G +G  G +GARG+PG    PGP G TG  G  G  G+ G PG++G P
Sbjct: 774  GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833

Query: 559  GK------------PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 606
            G              GP G  G  G+ G PG PG KG AG  G  G  G PG  G +G P
Sbjct: 834  GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 607  GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL---PGLPGPPGLPGMK 663
            G +G  G  GP G  G PGS G +GP G  G PG  G LG PG    PGL G PG  G  
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953

Query: 664  GDRGVVGEPGPKGEQGASGEEGE---------AGERGELGDIGLPGPKGSAGNPGEPGLR 714
            GDRG  G PG  G++G  GE+G+         AG  G+ G +G+PG +G  G PG PG  
Sbjct: 954  GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA 1013

Query: 715  GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHF 774
            G  G  G  G  G +GPPGP G  G  G  G PG +GP G   T      V  R      
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG----- 1068

Query: 775  AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG-- 832
                    R D G  GLPG  G PG PGP G  G  GQ G  G  G  GPPG  G RG  
Sbjct: 1069 -------DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121

Query: 833  ----PKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPG 887
                P+GD G+ G+RG  G +G  G  G  GLPG PGP     NG  G  G PG  G  G
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-----NGEQGSAGIPGPFGPRG 1176

Query: 888  VPGP------PGPPGLPGFCEPASCTMQAGQRAFNKGP 919
             PGP       G PG  G   P       G+ A  +GP
Sbjct: 1177 PPGPVGPSGKEGNPGPLGPIGPPGVRGSVGE-AGPEGP 1213



 Score =  417 bits (1073), Expect = e-116
 Identities = 251/547 (45%), Positives = 275/547 (50%), Gaps = 58/547 (10%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P  + P     ERG PGE+G PG  G PG  G+ G  G  GPKG PGP G  G+ G PG 
Sbjct: 701  PGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGL 760

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGE 374
             G PG  G  G  GP G  G IG KG +G  G  G+RG PG  G PGP GP G  G PG 
Sbjct: 761  QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820

Query: 375  LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA 434
             G VGP   PG RG PG  G  GP G +GF         A P G  G PG+ G  G  G 
Sbjct: 821  RGLVGP---PGSRGNPGSRGENGPTGAVGF---------AGPQGPDGQPGVKGEPGEPGQ 868

Query: 435  KGEIGEPGRQGHKGEEGDQGELGEVG------AQGPPGAQGLRGITGIVGDKGEKGARGL 488
            KG+ G PG QG  G  G  G  G  G       QGPPGA G  G  G VG  G  GA G 
Sbjct: 869  KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP 928

Query: 489  DG---EPGPQGLPGAPGDQGQRG---------PPGEAGPKGDRGAEGARGIPGLPGPKGD 536
             G   EPG +G PG  GD G  G         PPG  G KGD G +G  G  G PGP G 
Sbjct: 929  AGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGT 988

Query: 537  TG------LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 590
            TG      +PG  G  G+PG+PG  G PGK GP G  G +G PG  G PG+ G  GE   
Sbjct: 989  TGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE--- 1045

Query: 591  TGAPGKPGQMGNSGKPGQQGPPGEVGPRG---PQGLPGSRGELGPVGSPGLPGKLGSLGS 647
               PG  G  GN G PG+ G  GE G RG   P GLPGS+G  G  G  G PG  G  G 
Sbjct: 1046 ---PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD 1102

Query: 648  PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP------ 701
            PG  G  GPPG  G +G  G  G  G KG+ G  G+ G+ G RG  G  GLPGP      
Sbjct: 1103 PGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGE 1162

Query: 702  KGSAGNPGE------PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR 755
            +GSAG PG       PG  GP G  G PG  GP GPPG RG  GE G  G PG  GPPG 
Sbjct: 1163 QGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGP 1222

Query: 756  APTDQHI 762
                 H+
Sbjct: 1223 PGPPGHL 1229



 Score =  414 bits (1063), Expect = e-115
 Identities = 278/680 (40%), Positives = 313/680 (46%), Gaps = 110/680 (16%)

Query: 338 GSKGQKGEPG-VPGSRGFPGRGIPGPPGPPGTAGLPGELG---RVGPVGDPGRRGPPGPP 393
           G KGQKGEPG VP   G  GR  PGP GPPG+ G  GE G   R GP G  G  G PG P
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGR--PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVP 167

Query: 394 GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL-------------PGMRGHKGAKGEIGE 440
           G PG  G  G H   P       P  +   GL             PG  G  G +G  G 
Sbjct: 168 GQPGAPGPPG-HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGL 226

Query: 441 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 500
            G+QG  G  G  GE G+ G  GP G++G  G  G  G+ GE G  G  GE G  G PGA
Sbjct: 227 QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286

Query: 501 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 560
            G  G  G PG  G +G +G EG +G  G PG KG+ G  G  G  G  G  G  GE G+
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346

Query: 561 PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP------GE 614
            GP G  G +G  G+PG PG  G  G  GS+G PG PG  G +G  G +GP       GE
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 615 VGPRGPQGLPGSRGEL---------GPVGSPGLPGKLGSLGSPGLP------------GL 653
            GP GP G PG  G +         GP GSPG  G  GS G PG P            G 
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 654 PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL 713
           PG PG+PG KG+ G  GEPGP G QG  G  GE G+RG  GD G  GP G  G  G PG 
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 714 RGPEGSRGLP---GVEGPRGP---------------PGPRGVQGEQGATGLPGVQGPPGR 755
           RG  GS GLP   G +G RGP               PG  G+ G +G TG PGVQGP G+
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 756 -----APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFP 810
                AP +                   +   R   G+ GLPG  G  G PG PGE G  
Sbjct: 587 LGPLGAPGE-----------DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 811 GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------------RGPNGLPGAI 857
           G  G RG PG  G  G  G  GP G  GE+GE+GPPG              G  G PG  
Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695

Query: 858 GLPGDPGPAS----YGRNGRDGERGPPGVAGIP------------GVPGPPGPPGLPGFC 901
           G+PGDPG        G  G  GERG PG+ G+P            G  G PGP G PG  
Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755

Query: 902 EPASCTMQAGQRAFNKGPDP 921
            P       G+R     P P
Sbjct: 756 GPPGLQGMPGERGIAGTPGP 775



 Score =  337 bits (864), Expect = 3e-92
 Identities = 205/495 (41%), Positives = 237/495 (47%), Gaps = 85/495 (17%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            GP G  GP G PG  G PG+ G+ G+RG  G PGP G  G  G+ GA G  G  GA GL 
Sbjct: 741  GPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLP 800

Query: 329  GPDGSPGSIGSKGQKGEPGV------PGSRGFPGR-------------GIPGPPGPPGTA 369
            GP G PG  G  G+KGEPG       PGSRG PG              G  GP G PG  
Sbjct: 801  GPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVK 860

Query: 370  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL---- 425
            G PGE G+ G  G PG +G  G PGP GP G  G   G        PPG +G+PG     
Sbjct: 861  GEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG---TQGPPGATGFPGSAGRV 917

Query: 426  --PGMRGHKGAKGEIGEPGRQGHKG------------------------EEGDQGELGEV 459
              PG  G  G  G +GEPG++G  G                        ++GD GE G+ 
Sbjct: 918  GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977

Query: 460  GAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 519
            G  GPPG  G  G  GIVG  G++G RG+ G PGP G PG  G  G  G  G  GP G  
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 520  GAEGARGIPGLPGPKGDTGLPGVDGR---------DGIPGMPGTKGEPGKPGP---PGDA 567
            G+ G  G PG  GP G+ G PG DG           G  G+PG++G PG PGP   PGDA
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097

Query: 568  GLQGLPGVPG------------IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G +G PG  G            +PG +G  G+KG  G  G  GQ G+ G  G QG PG  
Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157

Query: 616  GPRGPQGLPGSRGELGPVGSPGL---------PGKLGSLGSPGLPGLPGPPGLPGMKGDR 666
            GP G QG  G  G  GP G PG          PG LG +G PG+ G  G  G  G  G+ 
Sbjct: 1158 GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP 1217

Query: 667  GVVGEPGPKGEQGAS 681
            G  G PGP G   A+
Sbjct: 1218 GPPGPPGPPGHLTAA 1232



 Score = 91.3 bits (225), Expect = 4e-18
 Identities = 52/124 (41%), Positives = 61/124 (49%), Gaps = 16/124 (12%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP------PGPPGPAGEPGKPG 314
            P     ++G  G++G  G  G  G  G+ G+ G  GP G       PGP GP G PG  G
Sbjct: 1123 PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVG 1182

Query: 315  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPG--TAGLP 372
              GK G PG  G  GP G  GS+G  G +G PG PG         PGPPGPPG  TA L 
Sbjct: 1183 PSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGP--------PGPPGPPGHLTAALG 1234

Query: 373  GELG 376
              +G
Sbjct: 1235 DIMG 1238


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  536 bits (1381), Expect = e-152
 Identities = 323/740 (43%), Positives = 364/740 (49%), Gaps = 108/740 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    PS     +G  G+ G PG PG PG  G+ G  GD GP+G  GP G  GE G+PG 
Sbjct: 530  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589

Query: 316  PGKPGT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPGT 368
            PG  G    PG  G  GP G+ G  G  G+KG PG PG RG PG+    G  GPPGP G 
Sbjct: 590  PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649

Query: 369  AGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPG 427
            AG  GE G  GP G  G  GPPGPPG  G  G  G   G+   P    P G  G+PG  G
Sbjct: 650  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFPGERG 708

Query: 428  MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL---RGITGIVGDKGEK- 483
              G +G +G  G PG  G  G +G  G  G  GAQGPPG QG+   RG  GI G KG++ 
Sbjct: 709  SPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 768

Query: 484  --------------GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
                          G RGL G  GP G  GA G++G+ GPPG AG  G RGA G RG  G
Sbjct: 769  DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 828

Query: 530  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 589
             PGP G  G PG DG+   PG  G +GE G+ G  G  G QG  G PG  G  GV G KG
Sbjct: 829  PPGPAGFAGPPGADGQ---PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 885

Query: 590  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            + GA G PG  G  G  G+ GPPG  G  GP G PG  G+ GP G+ G  G  G  G PG
Sbjct: 886  ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPG 945

Query: 650  LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
            L G  GPPG  G  GD G  G  GP G QG +G+ G  G  G+ G+ G PG  G +G PG
Sbjct: 946  LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 1005

Query: 710  EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
            + G  G  G RG P   GP GPPG  G  GE G  G PG  GPPGR              
Sbjct: 1006 KQGAPGASGDRGPP---GPVGPPGLTGPAGEPGREGSPGADGPPGR-------------- 1048

Query: 770  IQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGP------------------------ 803
                  + AA +K  R ++GA G PG PGPPG PGP                        
Sbjct: 1049 ------DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1102

Query: 804  ---------------------PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
                                 PGE G  G  G  GL G+ GPPG  G +G  G  G  G 
Sbjct: 1103 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1162

Query: 843  RGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901
            RGPPG  GP+G  GA G+PG  GP   G  GR GE GP G  G PG PGPPGPPG PG  
Sbjct: 1163 RGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPGNPGPPGPPGPPG-PGI- 1218

Query: 902  EPASCTMQAGQRAFNKGPDP 921
                 +  AG     KGPDP
Sbjct: 1219 ---DMSAFAGLGPREKGPDP 1235



 Score =  527 bits (1358), Expect = e-149
 Identities = 330/751 (43%), Positives = 366/751 (48%), Gaps = 121/751 (16%)

Query: 268 RGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP-------- 313
           RGPPG  G PGP      PG PG PG+ G  G RGP GPPG PG  GE GKP        
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268

Query: 314 ----GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 369
               GA G PGTPG  G+ G  G PG  G+KG+ G PGV G  G PG    G PGP G  
Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN--GSPGPMGPR 326

Query: 370 GLPGELGRVGPVGDPGRR------GPPGPPGPPGPRGTIGFHD----------------- 406
           GLPGE GR GP G  G R      GP GPPGP GP G  GF                   
Sbjct: 327 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 407 ------GDPLCP----------------------NACPPGRSGYPGLPGMRGHK------ 432
                 G+P  P                      +A  PG +G PG PG RG        
Sbjct: 387 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 433 ---GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP---------GAQGLRGITGIVGDK 480
              G KG+ GEPG  G KGE+G +GE G  G QG P         GA+G  G  G +G  
Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 481 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 540
           GE+GA G  G PG  GL G  G  G+RGP G AGPKG  G  G  G PGLPG +G TG P
Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566

Query: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV------AGEKGSTGAP 594
           G  G  G  G  G  GE G+PGPPG  G +G PGV G PG KG       AGEKG  GAP
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626

Query: 595 GKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 651
           G  G  G  G+ G  GPPG  GP   RG QG PG  G  G  G PG PG+ G  G  G+P
Sbjct: 627 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 652 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 711
           G  G PGL G +G+RG  GE G  G QG  G  G  G  G  G  G  GP G  G  G P
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746

Query: 712 GLRGPEGSRGLPGVEGPR------GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 765
           GL+G  G RG  G+ GP+      G  GP G  G+ G  GL G  GPPG A  +    +V
Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806

Query: 766 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP---GPPGPPGENGFPGQMGIRGLPGIK 822
                        A  +R ++G  G  G  GPP   G PG  GE G  GQ G  G PG +
Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 823 GPPGALGLRGPKGDLGEKGER---GPPGR----------GPNGLPGAIGLPGDPGPASY- 868
           GP GA G +GP G  G KG R   GPPG           GP G  G  G PG PGP+   
Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 869 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
           G  G  G+ GPPG AG PG+ GP GPPG  G
Sbjct: 927 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957



 Score =  526 bits (1356), Expect = e-149
 Identities = 310/680 (45%), Positives = 356/680 (52%), Gaps = 75/680 (11%)

Query: 265  TDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 324
            T  RGP G QGP G PG PG PG  G  G+ G  G PG  G AG PG  GAPG PG  G 
Sbjct: 380  TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439

Query: 325  DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGD 383
             G   P G+ G +G KGQ GEPG+ G +G  G +G PGP GP G  G  GE G+ G  G+
Sbjct: 440  PG---PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 496

Query: 384  PGRRGPPGPPGPPGPRGTIGFHDGDPLC----------PN--ACPPGRSGYPGLPGMRGH 431
            PG  GP GPPG  G  G  GF   D L           P+  A P G +G PG PG  G 
Sbjct: 497  PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA------ 485
             GA+G  G PG  G +G+ G  G  GE G  GPPG QG RG  G++G  G KGA      
Sbjct: 557  PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616

Query: 486  ---RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGA------RGIPGLPGPKGD 536
               +GL G PG +GLPG  G+ G  GPPG AGP G+RG +GA      +G+PG PGP G+
Sbjct: 617  AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 676

Query: 537  TGLP---GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGA 593
             G P   GV G  G PG+ G +GE G PG  G  G QGL G  G+PG  G  G KG++G 
Sbjct: 677  GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGP 736

Query: 594  PGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL 653
             G PG     G PG QG PGE G  G  G  G RG++G  G  G PGK    G  GL G 
Sbjct: 737  AGPPGA---QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK---DGGRGLTGP 790

Query: 654  PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP---GE 710
             GPPG  G  G++G VG PGP G  GA G  GE GE G  G  G  GP G+ G P   GE
Sbjct: 791  IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 711  PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 770
             G  G +G  G PG +GP G PGP+G  G  G  G  G QGPPG         +V     
Sbjct: 851  QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV----- 905

Query: 771  QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 830
                            G  G  G PGPPGPPGP G++G  G  G  G PG  G PG  G 
Sbjct: 906  ----------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 949

Query: 831  RGPKGDLGEKGERGPPGR----GPNGLP---GAIGLPGDPG----PASYGRNGRDGERGP 879
             GP G+ GE G+ GP G     GP GL    G +GLPG  G    P   G +G  G++G 
Sbjct: 950  AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 880  PGVAGIPGVPGPPGPPGLPG 899
            PG +G  G PGP GPPGL G
Sbjct: 1010 PGASGDRGPPGPVGPPGLTG 1029



 Score =  509 bits (1310), Expect = e-144
 Identities = 300/711 (42%), Positives = 350/711 (49%), Gaps = 96/711 (13%)

Query: 267 ERGPPGE-------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 319
           ++G PG+       +GPPGP GP G  G  G  GD+G KG PGP G  GEPG PG PG P
Sbjct: 105 QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPP 164

Query: 320 GTPGADGLTG------------------------PDGSPGSIGSKGQKGEPGVPGSRGFP 355
           G PG  G  G                          G  G +G +G  G  G PG +GF 
Sbjct: 165 GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQ 224

Query: 356 GRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPP------GPPGPRGTIGFHDGDP 409
           G   PG PG PG +G  G  G  GP G PG  G  G P      GPPGP+G  GF     
Sbjct: 225 GN--PGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF----- 277

Query: 410 LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 469
                      G PGLPG++GH+G  G  G  G  G  G +G+ G  GE G+ GP G +G
Sbjct: 278 ----------PGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRG 327

Query: 470 LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
           L G  G  G  G  GARG DG+PGP G PG  G  G  G PG  G KG+ G  GARG  G
Sbjct: 328 LPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387

Query: 530 LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 589
             GP+G+ G PG  G  G  G PGT G PG  G  G  G+ G PG PG  G  G  G  G
Sbjct: 388 AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATG 447

Query: 590 STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
             G  G+ G+ G +G  G+QGP GE GP GPQG PG  GE G  G+ G PG +G +G PG
Sbjct: 448 PLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPG 507

Query: 650 LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
             G PG  G PG  G  G  G PG +G  G +G +G  G+ G  G+ GLPG +G  G PG
Sbjct: 508 ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPG 567

Query: 710 EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVC 766
           + G +G  G  G PG +G  GPPGP+G +G+ G  G P   G  G PG+A          
Sbjct: 568 DAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA---------- 617

Query: 767 MRVIQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 824
                E     A  L+      G TG  G PGP GP G  GE G PG  G +GLPG  GP
Sbjct: 618 ----GEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 673

Query: 825 P---------------GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYG 869
           P               GA GL GP+G+ G  GERG P  G  GL G  GLPG PG  + G
Sbjct: 674 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP--GAQGLQGPRGLPGTPG--TDG 729

Query: 870 RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPD 920
             G  G  GPPG  G PG+ G PG  G  G   P       G+    KGP+
Sbjct: 730 PKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE----KGPE 776



 Score =  500 bits (1287), Expect = e-141
 Identities = 313/730 (42%), Positives = 357/730 (48%), Gaps = 82/730 (11%)

Query: 261 PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG------ 314
           P     E+GP G++G  G  G PG  G DG  G  G  GPPGPPGP G PG  G      
Sbjct: 124 PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQM 183

Query: 315 ---------------APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RG 358
                            G  G  G  G  GP G+PG  G +G  GEPG PG  G  G RG
Sbjct: 184 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG 243

Query: 359 IPGPPGPP---GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-----HDGDPL 410
            PGPPG P   G AG PG+ G  GP G  G RG PG PG PG +G  G+       G+  
Sbjct: 244 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 303

Query: 411 CP----NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466
            P     +  PG +G PG  G RG  G +G  G  G  G +G +G  G  G  G  GP G
Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 363

Query: 467 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 526
             G  G  G  G+ G  GARG +G  GP+G PG PG  G  G  G  G  G  GA+G+ G
Sbjct: 364 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG 423

Query: 527 IPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG 574
            PG+            PGP+G TG  G  G+ G PG+ G KGE G  G PG AG QG PG
Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 483

Query: 575 VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVG 634
             G  G +G  GE G  G  G PG+    G PG +G PG+ G  GP+G PG RG  G  G
Sbjct: 484 PAGEEGKRGARGEPGGVGPIGPPGE---RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 540

Query: 635 SPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 694
             G  G  G  G PGLPG  G  G PG  G +G VG  G  GE G  G  G  G RG+ G
Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG 600

Query: 695 DIGLPGPKGSAGNP---GEPGLRGPEGSRGLPGVE------GPRGPPGPRGVQGEQGA-- 743
            +G PGPKG+ G P   GE GL G  G RGLPG +      GP GP GP G +GEQGA  
Sbjct: 601 VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG 660

Query: 744 ----TGLPGVQGPPGRA--PTDQHIK-------QVCMRVIQEHFAEMAASLKRPDSGATG 790
                GLPG  GPPG    P DQ +         V  R  +    E  +   +   G  G
Sbjct: 661 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720

Query: 791 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-G 849
           LPG PG  GP G  G  G PG  G  GL G+ G  GA G+ GPKGD G+ GE+GP G  G
Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780

Query: 850 PNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP------GPPGLPGFCEP 903
            +G  G  G  G PGPA  G NG  GE GPPG AG  G  G P      GPPG  GF  P
Sbjct: 781 KDGGRGLTGPIGPPGPA--GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 838

Query: 904 ASCTMQAGQR 913
                Q G +
Sbjct: 839 PGADGQPGAK 848



 Score =  389 bits (998), Expect = e-108
 Identities = 236/546 (43%), Positives = 271/546 (49%), Gaps = 48/546 (8%)

Query: 411 CPNACPPGRSGYPGLPGMRGHKGAKGEI-------GEPGRQGHKGEEGDQGELGEVGAQG 463
           CP  CP   +   G PG +G KG  G+I       G PG QG  GE+G +G+ G+ G +G
Sbjct: 86  CP-ICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKG 144

Query: 464 PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG---------------------LPGAPG 502
            PG +G  G  G  G+ G  G  G  G PG  G                     + G  G
Sbjct: 145 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 503 DQGQRGPPGEAGPKGDRGAEGARGIPGLP------GPKGDTGLPGVDGRDGIPGMPGTKG 556
             G RGPPG AG  G +G +G  G PG P      GP+G  G PG  G DG  G PG  G
Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 264

Query: 557 EPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 616
           E G PGP G  G  G PG+PG+ G +G  G  G+ G  G PG  G SG PG+ G P   G
Sbjct: 265 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP---G 321

Query: 617 PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKG 676
           P GP+GLPG RG  GP G+ G  G  G  G  G PG  GP G PG  G  G  GE GP  
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP-- 379

Query: 677 EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736
             GA G EG  G RGE G  G PGP G++GNPG  G+ G +GS G PG+ G  G PGPRG
Sbjct: 380 -TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438

Query: 737 VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 796
             G QGATG  G +G  G         +   +          A     + G  G  G PG
Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 797 PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPG 855
             GP GPPGE G PG  G  G  G+ GP GA G RGP G  G KG  G PGR G  GLPG
Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 856 AIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP---GPPGLPGFCEPASCTMQAGQ 912
           A GL G PG A  G  G+ G  G PG  G PG PGP    G PG+ GF  P     + G 
Sbjct: 559 ARGLTGRPGDA--GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPG- 615

Query: 913 RAFNKG 918
           +A  KG
Sbjct: 616 KAGEKG 621



 Score =  365 bits (938), Expect = e-101
 Identities = 220/513 (42%), Positives = 247/513 (48%), Gaps = 56/513 (10%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 306
            P ++    L   I P       G  GE GPPGP G  G  G        G +G  GPPGP
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP------GERGETGPPGP 832

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP 365
            AG  G PGA G+PG  G  G  G  G  G+ G +G  G PG  G  G  G +G  G  GP
Sbjct: 833  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
            PG  G PG  GRVGP   PG  G PGPPGPPGP G  G            P G  G  G 
Sbjct: 893  PGATGFPGAAGRVGP---PGSNGNPGPPGPPGPSGKDG------------PKGARGDSGP 937

Query: 426  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
            PG  G  G +G  G PG +G  G++G        GA+GPPG QGL G  GIVG  G++G 
Sbjct: 938  PGRAGEPGLQGPAGPPGEKGEPGDDGPS------GAEGPPGPQGLAGQRGIVGLPGQRGE 991

Query: 486  RGLDGEPGPQGLP---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV 542
            RG  G PGP G P   GAPG  G RGPPG  GP            PGL GP G+ G  G 
Sbjct: 992  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP------------PGLTGPAGEPGREGS 1039

Query: 543  DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
             G DG PG  G  G  G  G  G  G  G PG PG PG  G  G++G  G  G  G MG 
Sbjct: 1040 PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1099

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 662
            SG  G +G  G  GPRG +G  G  GE G  G  G  G  G  G PG  G  G  G  G 
Sbjct: 1100 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159

Query: 663  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL 722
             G RG  G  GP G+ GA+G  G  G  G  G  G  GP G  GNPG PG  GP G    
Sbjct: 1160 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG---- 1215

Query: 723  PGVE-------GPR--GPPGPRGVQGEQGATGL 746
            PG++       GPR  GP   + ++ +Q A GL
Sbjct: 1216 PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1248



 Score =  288 bits (736), Expect = 2e-77
 Identities = 186/457 (40%), Positives = 204/457 (44%), Gaps = 85/457 (18%)

Query: 509 PPGEAGPKGDRGAEGARGIPGLPGP----------------------------------K 534
           P GE  P        A G PG  G                                   K
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 535 GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------------------LPGVP 576
           G+ G PG  GRDG PG PG  G PG PGPPG  GL G                  L  + 
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 577 GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP 636
           G  G  G  G  G  GAPG  G  GN G+PG+ G  G +GPRGP G PG  G+ G  G P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 637 GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 696
           G  G+ G  G  G  G PG PGLPG+KG RG  G  G KGE GA G +GE+G  GE G  
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320

Query: 697 GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 756
           G  GP+G  G  G  G  G  G+RG  G  GP GPPGP G  G  G  G PG +G  G  
Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG-- 378

Query: 757 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIR 816
           PT                A      + P  G  G PG PGP G  G PG +G PG  G  
Sbjct: 379 PTG---------------ARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422

Query: 817 GLPGIKGPPGALGLRGP------KGDLGEKGERGPPG-------RGPNGLPGAIGLPGDP 863
           G PGI G PG  G RGP       G LG KG+ G PG       +GP G PG  G  G P
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482

Query: 864 GPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 900
           GPA  G  G+ G RG PG  G  G PG  G PG  GF
Sbjct: 483 GPA--GEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517



 Score =  201 bits (511), Expect = 3e-51
 Identities = 138/404 (34%), Positives = 159/404 (39%), Gaps = 129/404 (31%)

Query: 611 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL---------------------------- 642
           P GE  P  P  L  + G+ GP G  G PG +                            
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 643 ---------------GSLGSPGLPGLPGPPGLPG------------------------MK 663
                          G+ G+PG PG PGPPG PG                        M+
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 664 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 723
           G  G +G  GP G  GA G +G  G  GE G+ G+ GP G  G PG PG  G +G  G P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 724 GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 783
           G  G RGPPGP+G +G  G  GLPGV+G  G    D                        
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD------------------------ 296

Query: 784 PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 843
              GA G  G PG  G  G PGENG PG MG RGLPG +G  G  G  G +G+ G+ G  
Sbjct: 297 ---GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353

Query: 844 GPPG-------------------------RGPNGLPGAIGLPGDPG----------PASY 868
           GPPG                         RGP G  G  G PG PG          P + 
Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 869 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 912
           G  G  G  G PG+AG PG PGP GPPG  G   P     Q G+
Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457



 Score =  166 bits (421), Expect = 7e-41
 Identities = 117/285 (41%), Positives = 132/285 (46%), Gaps = 45/285 (15%)

Query: 652 GLPGPPGLPGMKGD-RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGE 710
           G PGP G  G  GD + +VG  GP G QG +GE+G  G+RG+ G+ G PGP+G  G PG 
Sbjct: 98  GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157

Query: 711 PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 770
           P         G PG  GP GPPGP G+ G   A    G     G A          + V+
Sbjct: 158 P---------GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ---------LGVM 199

Query: 771 QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 830
           Q     M     R   G  G PG  G  G PG PGE G  G MG RG PG   PPG  G 
Sbjct: 200 QGPMGPMGP---RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGD 253

Query: 831 RGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGV 888
            G  G  G+ GERGPPG +G  G PG  GLPG  G   Y G +G  GE G PGV G  G 
Sbjct: 254 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313

Query: 889 PGP------------PGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           PG             PG  G  G   PA     AG R  +  P P
Sbjct: 314 PGENGSPGPMGPRGLPGERGRTG---PAGA---AGARGNDGQPGP 352


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  536 bits (1381), Expect = e-152
 Identities = 323/740 (43%), Positives = 364/740 (49%), Gaps = 108/740 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    PS     +G  G+ G PG PG PG  G+ G  GD GP+G  GP G  GE G+PG 
Sbjct: 461  PGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520

Query: 316  PGKPGT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPGT 368
            PG  G    PG  G  GP G+ G  G  G+KG PG PG RG PG+    G  GPPGP G 
Sbjct: 521  PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580

Query: 369  AGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPG 427
            AG  GE G  GP G  G  GPPGPPG  G  G  G   G+   P    P G  G+PG  G
Sbjct: 581  AGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFPGERG 639

Query: 428  MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL---RGITGIVGDKGEK- 483
              G +G +G  G PG  G  G +G  G  G  GAQGPPG QG+   RG  GI G KG++ 
Sbjct: 640  SPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 699

Query: 484  --------------GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 529
                          G RGL G  GP G  GA G++G+ GPPG AG  G RGA G RG  G
Sbjct: 700  DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETG 759

Query: 530  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 589
             PGP G  G PG DG+   PG  G +GE G+ G  G  G QG  G PG  G  GV G KG
Sbjct: 760  PPGPAGFAGPPGADGQ---PGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKG 816

Query: 590  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 649
            + GA G PG  G  G  G+ GPPG  G  GP G PG  G+ GP G+ G  G  G  G PG
Sbjct: 817  ARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPG 876

Query: 650  LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
            L G  GPPG  G  GD G  G  GP G QG +G+ G  G  G+ G+ G PG  G +G PG
Sbjct: 877  LQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG 936

Query: 710  EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
            + G  G  G RG P   GP GPPG  G  GE G  G PG  GPPGR              
Sbjct: 937  KQGAPGASGDRGPP---GPVGPPGLTGPAGEPGREGSPGADGPPGR-------------- 979

Query: 770  IQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGP------------------------ 803
                  + AA +K  R ++GA G PG PGPPG PGP                        
Sbjct: 980  ------DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGP 1033

Query: 804  ---------------------PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
                                 PGE G  G  G  GL G+ GPPG  G +G  G  G  G 
Sbjct: 1034 AGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGP 1093

Query: 843  RGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901
            RGPPG  GP+G  GA G+PG  GP   G  GR GE GP G  G PG PGPPGPPG PG  
Sbjct: 1094 RGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPAGPPGNPGPPGPPGPPG-PGI- 1149

Query: 902  EPASCTMQAGQRAFNKGPDP 921
                 +  AG     KGPDP
Sbjct: 1150 ---DMSAFAGLGPREKGPDP 1166



 Score =  527 bits (1358), Expect = e-149
 Identities = 330/751 (43%), Positives = 366/751 (48%), Gaps = 121/751 (16%)

Query: 268 RGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP-------- 313
           RGPPG  G PGP      PG PG PG+ G  G RGP GPPG PG  GE GKP        
Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 199

Query: 314 ----GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 369
               GA G PGTPG  G+ G  G PG  G+KG+ G PGV G  G PG    G PGP G  
Sbjct: 200 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN--GSPGPMGPR 257

Query: 370 GLPGELGRVGPVGDPGRR------GPPGPPGPPGPRGTIGFHD----------------- 406
           GLPGE GR GP G  G R      GP GPPGP GP G  GF                   
Sbjct: 258 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 317

Query: 407 ------GDPLCP----------------------NACPPGRSGYPGLPGMRGHK------ 432
                 G+P  P                      +A  PG +G PG PG RG        
Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377

Query: 433 ---GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP---------GAQGLRGITGIVGDK 480
              G KG+ GEPG  G KGE+G +GE G  G QG P         GA+G  G  G +G  
Sbjct: 378 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437

Query: 481 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 540
           GE+GA G  G PG  GL G  G  G+RGP G AGPKG  G  G  G PGLPG +G TG P
Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 497

Query: 541 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV------AGEKGSTGAP 594
           G  G  G  G  G  GE G+PGPPG  G +G PGV G PG KG       AGEKG  GAP
Sbjct: 498 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 557

Query: 595 GKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 651
           G  G  G  G+ G  GPPG  GP   RG QG PG  G  G  G PG PG+ G  G  G+P
Sbjct: 558 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 617

Query: 652 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 711
           G  G PGL G +G+RG  GE G  G QG  G  G  G  G  G  G  GP G  G  G P
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 677

Query: 712 GLRGPEGSRGLPGVEGPR------GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 765
           GL+G  G RG  G+ GP+      G  GP G  G+ G  GL G  GPPG A  +    +V
Sbjct: 678 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 737

Query: 766 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP---GPPGPPGENGFPGQMGIRGLPGIK 822
                        A  +R ++G  G  G  GPP   G PG  GE G  GQ G  G PG +
Sbjct: 738 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 797

Query: 823 GPPGALGLRGPKGDLGEKGER---GPPGR----------GPNGLPGAIGLPGDPGPASY- 868
           GP GA G +GP G  G KG R   GPPG           GP G  G  G PG PGP+   
Sbjct: 798 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 857

Query: 869 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
           G  G  G+ GPPG AG PG+ GP GPPG  G
Sbjct: 858 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 888



 Score =  526 bits (1356), Expect = e-149
 Identities = 310/680 (45%), Positives = 356/680 (52%), Gaps = 75/680 (11%)

Query: 265 TDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 324
           T  RGP G QGP G PG PG PG  G  G+ G  G PG  G AG PG  GAPG PG  G 
Sbjct: 311 TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 325 DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGD 383
            G   P G+ G +G KGQ GEPG+ G +G  G +G PGP GP G  G  GE G+ G  G+
Sbjct: 371 PG---PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGE 427

Query: 384 PGRRGPPGPPGPPGPRGTIGFHDGDPLC----------PN--ACPPGRSGYPGLPGMRGH 431
           PG  GP GPPG  G  G  GF   D L           P+  A P G +G PG PG  G 
Sbjct: 428 PGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487

Query: 432 KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA------ 485
            GA+G  G PG  G +G+ G  G  GE G  GPPG QG RG  G++G  G KGA      
Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547

Query: 486 ---RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGA------RGIPGLPGPKGD 536
              +GL G PG +GLPG  G+ G  GPPG AGP G+RG +GA      +G+PG PGP G+
Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607

Query: 537 TGLP---GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGA 593
            G P   GV G  G PG+ G +GE G PG  G  G QGL G  G+PG  G  G KG++G 
Sbjct: 608 GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGP 667

Query: 594 PGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL 653
            G PG     G PG QG PGE G  G  G  G RG++G  G  G PGK    G  GL G 
Sbjct: 668 AGPPGA---QGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGK---DGGRGLTGP 721

Query: 654 PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP---GE 710
            GPPG  G  G++G VG PGP G  GA G  GE GE G  G  G  GP G+ G P   GE
Sbjct: 722 IGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGE 781

Query: 711 PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 770
            G  G +G  G PG +GP G PGP+G  G  G  G  G QGPPG         +V     
Sbjct: 782 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRV----- 836

Query: 771 QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 830
                           G  G  G PGPPGPPGP G++G  G  G  G PG  G PG  G 
Sbjct: 837 ----------------GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGP 880

Query: 831 RGPKGDLGEKGERGPPGR----GPNGLP---GAIGLPGDPG----PASYGRNGRDGERGP 879
            GP G+ GE G+ GP G     GP GL    G +GLPG  G    P   G +G  G++G 
Sbjct: 881 AGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 880 PGVAGIPGVPGPPGPPGLPG 899
           PG +G  G PGP GPPGL G
Sbjct: 941 PGASGDRGPPGPVGPPGLTG 960



 Score =  512 bits (1318), Expect = e-145
 Identities = 301/697 (43%), Positives = 350/697 (50%), Gaps = 68/697 (9%)

Query: 267 ERGPPGE----QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTP 322
           ++G PG+     GP GPPGP G  G  G  GDRG KG  G PGP G  G+PG PG PG P
Sbjct: 36  QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPP 95

Query: 323 GADGLTGPDGSPGSIGSK---------------GQKGEPGVPGSRGFPGRGIPGPPGPPG 367
           G  G  GP G  G+  ++                 +G  G  G RG PG    G PGP G
Sbjct: 96  GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA--GAPGPQG 153

Query: 368 TAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----FHDGDPLCPNACPPGRSGYP 423
             G PGE G  G  G  G RGPPGPPG PG  G  G      +  P  P     G  G P
Sbjct: 154 FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGA-RGFPGTP 212

Query: 424 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 483
           GLPG++GH+G  G  G  G  G  G +G+ G  GE G+ GP G +GL G  G  G  G  
Sbjct: 213 GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272

Query: 484 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 543
           GARG DG+PGP G PG  G  G  G PG  G KG+ G  GARG  G  GP+G+ G PG  
Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP 332

Query: 544 GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 603
           G  G  G PGT G PG  G  G  G+ G PG PG  G  G  G  G  G  G+ G+ G +
Sbjct: 333 GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392

Query: 604 GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 663
           G  G+QGP GE GP GPQG PG  GE G  G+ G PG +G +G PG  G PG  G PG  
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452

Query: 664 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 723
           G  G  G PG +G  G +G +G  G+ G  G+ GLPG +G  G PG+ G +G  G  G P
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512

Query: 724 GVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 780
           G +G  GPPGP+G +G+ G  G P   G  G PG+A               E     A  
Sbjct: 513 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--------------GEKGLPGAPG 558

Query: 781 LK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP------------- 825
           L+      G TG  G PGP GP G  GE G PG  G +GLPG  GPP             
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618

Query: 826 --GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVA 883
             GA GL GP+G+ G  GERG P  G  GL G  GLPG PG  + G  G  G  GPPG  
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSP--GAQGLQGPRGLPGTPG--TDGPKGASGPAGPPGAQ 674

Query: 884 GIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPD 920
           G PG+ G PG  G  G   P       G+    KGP+
Sbjct: 675 GPPGLQGMPGERGAAGIAGPKGDRGDVGE----KGPE 707



 Score =  500 bits (1287), Expect = e-141
 Identities = 313/730 (42%), Positives = 357/730 (48%), Gaps = 82/730 (11%)

Query: 261 PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG------ 314
           P     E+GP G++G  G  G PG  G DG  G  G  GPPGPPGP G PG  G      
Sbjct: 55  PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQM 114

Query: 315 ---------------APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RG 358
                            G  G  G  G  GP G+PG  G +G  GEPG PG  G  G RG
Sbjct: 115 AGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRG 174

Query: 359 IPGPPGPP---GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-----HDGDPL 410
            PGPPG P   G AG PG+ G  GP G  G RG PG PG PG +G  G+       G+  
Sbjct: 175 PPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAG 234

Query: 411 CP----NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 466
            P     +  PG +G PG  G RG  G +G  G  G  G +G +G  G  G  G  GP G
Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG 294

Query: 467 AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARG 526
             G  G  G  G+ G  GARG +G  GP+G PG PG  G  G  G  G  G  GA+G+ G
Sbjct: 295 GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAG 354

Query: 527 IPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG 574
            PG+            PGP+G TG  G  G+ G PG+ G KGE G  G PG AG QG PG
Sbjct: 355 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 414

Query: 575 VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVG 634
             G  G +G  GE G  G  G PG+    G PG +G PG+ G  GP+G PG RG  G  G
Sbjct: 415 PAGEEGKRGARGEPGGVGPIGPPGE---RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 471

Query: 635 SPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 694
             G  G  G  G PGLPG  G  G PG  G +G VG  G  GE G  G  G  G RG+ G
Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG 531

Query: 695 DIGLPGPKGSAGNP---GEPGLRGPEGSRGLPGVE------GPRGPPGPRGVQGEQGA-- 743
            +G PGPKG+ G P   GE GL G  G RGLPG +      GP GP GP G +GEQGA  
Sbjct: 532 VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG 591

Query: 744 ----TGLPGVQGPPGRA--PTDQHIK-------QVCMRVIQEHFAEMAASLKRPDSGATG 790
                GLPG  GPPG    P DQ +         V  R  +    E  +   +   G  G
Sbjct: 592 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651

Query: 791 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-G 849
           LPG PG  GP G  G  G PG  G  GL G+ G  GA G+ GPKGD G+ GE+GP G  G
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711

Query: 850 PNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP------GPPGLPGFCEP 903
            +G  G  G  G PGPA  G NG  GE GPPG AG  G  G P      GPPG  GF  P
Sbjct: 712 KDGGRGLTGPIGPPGPA--GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP 769

Query: 904 ASCTMQAGQR 913
                Q G +
Sbjct: 770 PGADGQPGAK 779



 Score =  365 bits (938), Expect = e-101
 Identities = 220/513 (42%), Positives = 247/513 (48%), Gaps = 56/513 (10%)

Query: 247  PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 306
            P ++    L   I P       G  GE GPPGP G  G  G        G +G  GPPGP
Sbjct: 710  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAP------GERGETGPPGP 763

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP 365
            AG  G PGA G+PG  G  G  G  G  G+ G +G  G PG  G  G  G +G  G  GP
Sbjct: 764  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
            PG  G PG  GRVGP   PG  G PGPPGPPGP G  G            P G  G  G 
Sbjct: 824  PGATGFPGAAGRVGP---PGSNGNPGPPGPPGPSGKDG------------PKGARGDSGP 868

Query: 426  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
            PG  G  G +G  G PG +G  G++G        GA+GPPG QGL G  GIVG  G++G 
Sbjct: 869  PGRAGEPGLQGPAGPPGEKGEPGDDGPS------GAEGPPGPQGLAGQRGIVGLPGQRGE 922

Query: 486  RGLDGEPGPQGLP---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV 542
            RG  G PGP G P   GAPG  G RGPPG  GP            PGL GP G+ G  G 
Sbjct: 923  RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGP------------PGLTGPAGEPGREGS 970

Query: 543  DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
             G DG PG  G  G  G  G  G  G  G PG PG PG  G  G++G  G  G  G MG 
Sbjct: 971  PGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGP 1030

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 662
            SG  G +G  G  GPRG +G  G  GE G  G  G  G  G  G PG  G  G  G  G 
Sbjct: 1031 SGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090

Query: 663  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL 722
             G RG  G  GP G+ GA+G  G  G  G  G  G  GP G  GNPG PG  GP G    
Sbjct: 1091 SGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPG---- 1146

Query: 723  PGVE-------GPR--GPPGPRGVQGEQGATGL 746
            PG++       GPR  GP   + ++ +Q A GL
Sbjct: 1147 PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGL 1179



 Score =  165 bits (417), Expect = 2e-40
 Identities = 116/283 (40%), Positives = 131/283 (46%), Gaps = 45/283 (15%)

Query: 654 PGPPGLPGMKGD-RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 712
           PGP G  G  GD + +VG  GP G QG +GE+G  G+RG+ G+ G PGP+G  G PG P 
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP- 89

Query: 713 LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
                   G PG  GP GPPGP G+ G   A    G     G A          + V+Q 
Sbjct: 90  --------GNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ---------LGVMQG 132

Query: 773 HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
               M     R   G  G PG  G  G PG PGE G  G MG RG PG   PPG  G  G
Sbjct: 133 PMGPMGP---RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPG---PPGKPGDDG 186

Query: 833 PKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPG 890
             G  G+ GERGPPG +G  G PG  GLPG  G   Y G +G  GE G PGV G  G PG
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG 246

Query: 891 P------------PGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
                        PG  G  G   PA     AG R  +  P P
Sbjct: 247 ENGSPGPMGPRGLPGERGRTG---PAGA---AGARGNDGQPGP 283


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  532 bits (1371), Expect = e-151
 Identities = 314/683 (45%), Positives = 353/683 (51%), Gaps = 79/683 (11%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P   T + GP G  G  GP GPPG  G +G  G  G  GP GPPGP G+ G PG PG+ G
Sbjct: 923  PRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRG 982

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
              G  G TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G 
Sbjct: 983  ETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG-----PPGPPGEQGLPGLAGKEGT 1037

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDP-------LCPNACPPGRSGYPGLPGMRGHKG 433
             GDPG  G PG  GPPG RG  G   G P       L  N  PPG  G  G PG RG  G
Sbjct: 1038 KGDPGPAGLPGKDGPPGLRGFPGDR-GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096

Query: 434  AKGEIGEPGR---QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 490
            A G IG PGR   QG  G  G++G  GE G QGP G  GL+G  G+ G  G  G  G DG
Sbjct: 1097 AAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG 1156

Query: 491  EPGPQGLPG---APGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL---PGVDG 544
            + G  G PG   + GD+G++GPPG  GP+G  G  G  G  G PGP+G  GL    G +G
Sbjct: 1157 DKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEG 1216

Query: 545  RDGIPGMPGTKGEPGKPGPPG------DAGLQGLPGVPG------IPGAKGVAGEKGSTG 592
              G PG PG  G  G PGPPG      D G  G PG PG       PGA G  G  G  G
Sbjct: 1217 PRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIG 1276

Query: 593  APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 652
             PG  G+ G  G+ G+ G PGE GP GP+G  G +GE GP G+ G PG  G  G  G  G
Sbjct: 1277 NPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKG 1336

Query: 653  LPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG 712
             PGP G PG   D G  GEPGP G+ G  G++G+ GE G+ G    PGP G  G  G PG
Sbjct: 1337 SPGPVGFPG---DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS---PGPTGEPGPSGPPG 1390

Query: 713  LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
             RGP G  G  G +G +G  G  G++G  G TG  G QG PG+   D       +R I  
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG------LRGIPG 1444

Query: 773  HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
               E             GLPG PGP GPPGP G  G PG  G  G  G KG PG +GL G
Sbjct: 1445 PVGEQ------------GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIG 1492

Query: 833  PKGDLGEKGERGPPG----------------RGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            P G+ GEKG+RG PG                 GP G PG  GLPG PGP      G  G 
Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGP-----KGAKGS 1547

Query: 877  RGPPGVAGIPGVPGPPGPPGLPG 899
             GP G  G  G PGPPGPPG PG
Sbjct: 1548 SGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  531 bits (1368), Expect = e-150
 Identities = 320/731 (43%), Positives = 372/731 (50%), Gaps = 137/731 (18%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPPGPAGEPGK------------P 313
            GP G  G PGP GPPG  G+ G  GD GP+GP    GPPGPAG+PG+            P
Sbjct: 562  GPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMP 621

Query: 314  GAPGKPGTPGADGLT------------GPDGSPGSIGSKGQKGEPGVPGSRGFPG----- 356
            G  G  G  G DGL             GP G PG  G  G++G+ G  G RG PG     
Sbjct: 622  GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681

Query: 357  -----RGIPGPPGPPGTAGL---PGELGRVGPVGD---PGRRGPPGPPGPPGPRGTIGFH 405
                 +G PGPPGPPG  G+   PG  G VGP G+   PG++G PG  G PGP+G IG  
Sbjct: 682  GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIG-- 739

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP 465
                      PPG  G  G PG+ G  GA G  G PG++G  GE+G QG  G  G  G P
Sbjct: 740  ----------PPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789

Query: 466  GAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPP---GEAGPKGDRGAE 522
            G +G++G  GI G KG KG +G DG PG +G  G  GD+G+ GPP   GE GP+G +G  
Sbjct: 790  GPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRG 849

Query: 523  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAK 582
            G  G PG  GP G+ G  GV G  G PG  G KG  G PG PG  G +G  G PG PG +
Sbjct: 850  GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPR 909

Query: 583  ------GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ---GLPGSRGELGPV 633
                  G  GE+G  G  GKPG  GNSG  G  GPPGE GP GPQ   G PG +G  GP 
Sbjct: 910  GQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPP 969

Query: 634  GSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 693
            G  GLPG  G  G  G  G  GPPG PG+ G +G  GE GP GE+G  G  G  GE+G  
Sbjct: 970  GKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP 1029

Query: 694  GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 753
            G  G  G KG  G  G PG  GP G RG PG  G  GP G  G++G +G  G PG  G P
Sbjct: 1030 GLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP 1089

Query: 754  G-RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 812
            G R P                            +G  G+PGRPGP GPPGP GE G PG+
Sbjct: 1090 GERGPAGA-------------------------AGPIGIPGRPGPQGPPGPAGEKGAPGE 1124

Query: 813  MGIR------------GLPGIKGPPGALGLRGPKGDLGE---------KGERGPPG---- 847
             G +            GLPG  GP G  G  G KG++GE         KGE+GPPG    
Sbjct: 1125 KGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP 1184

Query: 848  RGPNGLPGAIGLPGDPGPAS----YGRNGRDGER---GPPGVAGIPGVPGPP-------- 892
            +GP G PG  G  G+PGP      +G+ G +G R   GPPG  G+ G+PGPP        
Sbjct: 1185 QGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD 1244

Query: 893  ----GPPGLPG 899
                GPPG PG
Sbjct: 1245 VGQMGPPGPPG 1255



 Score =  531 bits (1367), Expect = e-150
 Identities = 320/755 (42%), Positives = 368/755 (48%), Gaps = 116/755 (15%)

Query: 259  ITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPK---GPPGPPGPAGEPGKPGA 315
            + P     E GP G  GP GPPGPPG PG+ G+DG  GPK   GP G PGP G+ G PGA
Sbjct: 669  VGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGA 728

Query: 316  PGKPGTPGA---DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGL 371
             G PG  GA    G  GP G PG  G  G  G PG PG  G PG +G  GPPGP G  G 
Sbjct: 729  QGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGY 788

Query: 372  P---------------------------------------GELGRVGPVGDPGRRGP--- 389
            P                                       GE+G  GP G+ G  GP   
Sbjct: 789  PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGR 848

Query: 390  ------PGPPGPPGPRGTIGFHDGDPLCP-NACPPGRSGYPGLPGMRGHKGAKGEIGEPG 442
                  PGP GPPG +G +G   G P  P    P G  G+PG PG  G KG +G  G+PG
Sbjct: 849  GGPNGDPGPLGPPGEKGKLGV-PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPG 907

Query: 443  RQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE---PGPQGLPG 499
             +G +G  G +GE G  G  G PG +G  G  G  G  GE+G  G  G    PGP+G PG
Sbjct: 908  PRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPG 967

Query: 500  APGD---------------QGQRGPP------GEAGPKGDRGAEGARGIPGLPGPKGDTG 538
             PG                QG+ GPP      G  GP G+ G  G RG PG PGP G+ G
Sbjct: 968  PPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQG 1027

Query: 539  LPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG 598
            LPG+ G++G  G PG  G PGK GPP   GL+G PG  G+PG  G  G KG+ G PG PG
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPP---GLRGFPGDRGLPGPVGALGLKGNEGPPGPPG 1084

Query: 599  QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG 658
                +G PG++GP G  GP G  G PG +G  GP G  G PG+ G  G  G  GL GP G
Sbjct: 1085 P---AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVG 1141

Query: 659  LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 718
            LPG  G  G  GE G KGE G  G++G  G++GE G  G  GP+G  G PG  G  G  G
Sbjct: 1142 LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPG 1201

Query: 719  SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 778
             RG  G+ G +G  GPRG  G  G  GL G+ GPPG       + Q+             
Sbjct: 1202 PRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM---------GPPG 1252

Query: 779  ASLKRPDSGATGLPGRPGPP---GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 835
                R  SGA G  G  GPP   G PG  GE G PG+ G  GLPG  GPPG  G RG KG
Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKG 1312

Query: 836  DLGEKGERGPPG-------RGPNGLPGAIGLPGDPGPASY----------GRNGRDGERG 878
            + G  G  GPPG        GP G PG +G PGDPGP             G  G DGE G
Sbjct: 1313 ESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG 1372

Query: 879  PPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
              G  G  G PGP GPPG  G   PA    + G++
Sbjct: 1373 QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEK 1407



 Score =  522 bits (1345), Expect = e-148
 Identities = 318/715 (44%), Positives = 366/715 (51%), Gaps = 85/715 (11%)

Query: 256  PARITPSQTTDERGPPGEQGPPGP---PGPPGVPGIDGIDGDRGPKGPPGPPG------- 305
            P R   + +   RG PG+ GP G     G  G+PG  G  GD GP GPPGPPG       
Sbjct: 606  PGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGD 665

Query: 306  -----PAGEPGKP------GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGF 354
                 P G PG+P      G  G PG PG  G+TG DG PG  G+ G +GEPG PG +G 
Sbjct: 666  DGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGN 725

Query: 355  PG-RGIPGP---------PGPPGTAGLPGELGRVGPVGDPGRRGPPGP---PGPPGPRGT 401
            PG +G+PGP          GP G  GLPG  G  GP G PG+ GPPG     GPPGP+G 
Sbjct: 726  PGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGP 785

Query: 402  IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461
            IG+            PG  G  G  G+RG KG KGE GE G  G KG+ G +G+ GE+G 
Sbjct: 786  IGY------------PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGP 833

Query: 462  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 521
             GP G  G  G  G  G  G+ G  G  GE G  G+PG PG  G++GP G  G  G  GA
Sbjct: 834  PGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGA 893

Query: 522  ---EGARGIPGLPGPKGD---TGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGL 572
               +G RG PG PGP+G    TG  G  G  GI G PG KG     G  GPPG+ G  G 
Sbjct: 894  NGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP 953

Query: 573  PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS---GKPGQQGPPGEVGPRGP--------- 620
             G  G PG KG  G  G  G PG PGQ G +   GK G  GPPG VGP+GP         
Sbjct: 954  QGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE 1013

Query: 621  QGLPGSRGELGPVGSPGLPGKLGSLGSP---GLPGLPGPPGLPGMKGDRGV---VGEPGP 674
            +G PG  G  G  G PGL GK G+ G P   GLPG  GPPGL G  GDRG+   VG  G 
Sbjct: 1014 RGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGL 1073

Query: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            KG +G  G  G AG  GE G  G  GP G  G PG  G  GP G +G PG +GP+GP G 
Sbjct: 1074 KGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGR 1133

Query: 735  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794
             G+QG  G  G  G  GPPG       I +   +  +    E          G  G PG 
Sbjct: 1134 DGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193

Query: 795  PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR------GPKGDLGEKGERGPPG- 847
             G  G PGP G+ G  GQ G  G  G  GPPG +GL+      G KG+ G+ G+ GPPG 
Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253

Query: 848  ---RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
               RGP+G PGA G  G PG    G  G  GE+G PG AG PG+PG  GPPG  G
Sbjct: 1254 PGPRGPSGAPGADGPQGPPG--GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306



 Score =  520 bits (1340), Expect = e-147
 Identities = 319/739 (43%), Positives = 366/739 (49%), Gaps = 142/739 (19%)

Query: 267  ERGPPGE----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316
            E+G  GE          +GPPGP GP G+PG         P G  GP G  G+PG+ G P
Sbjct: 451  EKGQKGEPAIIEPGMLIEGPPGPEGPAGLPG---------PPGTMGPTGQVGDPGERGPP 501

Query: 317  GKPGTPGADGLTGPDGSP----------GSIGSKG-----QKGEP------------GVP 349
            G+PG PGADGL GP G+           G  GSKG     Q+ +             G  
Sbjct: 502  GRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPA 561

Query: 350  GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP 409
            G  G  GR  PGP GPPG+ GL GE G VGP G  G +GPPGP G PG RG  G  DG  
Sbjct: 562  GPMGLTGR--PGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAG-SDGAR 618

Query: 410  LCPNACPP----GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------- 458
              P    P    G  G  GLPG +GH+G  G  G PG  G  GE GD GE+G        
Sbjct: 619  GMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEP 678

Query: 459  -----VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEA 513
                 +G +GPPG  G  G+TG+ G  G KG  G  GEPGP G  G PG QG  GP G  
Sbjct: 679  GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738

Query: 514  GPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP 573
            GP G++G  G  G+PG+PG  G    PG  G++G PG  G +G PG  GP G  G +G+ 
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGP---PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVK 795

Query: 574  GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSRGEL 630
            G  GI G KG  GEKG  G PG  G MG  G  G+ GPP   GE GP GP+G  G  G+ 
Sbjct: 796  GADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDP 855

Query: 631  GPVGSPGLPGKLGSLGSPGLPGLPGP------PGLPGMKGDRGVVGEPGPKGEQGASGEE 684
            GP+G PG  GKLG  G PG PG  GP      PG PG  G++G  G PG  G +G  G  
Sbjct: 856  GPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPT 915

Query: 685  GEAGERGELGDIGLPGPKGS------AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV- 737
            G  GERG  G  G PGPKG+      AG PGE G  GP+G  G PG +GP GPPG  G+ 
Sbjct: 916  GPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLP 975

Query: 738  --QGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP 795
               G++G TG  G  GPPG                            +  +G TG  G  
Sbjct: 976  GHPGQRGETGFQGKTGPPG---------------------PPGVVGPQGPTGETGPMGER 1014

Query: 796  GPPGPPGPPGENGFPGQMGIRGL---------------PGIKGPPGALGLRGPKGDLGEK 840
            G PGPPGPPGE G PG  G  G                PG++G PG  GL GP G LG K
Sbjct: 1015 GHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLK 1074

Query: 841  GERGPPG----------RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIP 886
            G  GPPG          RGP G  G IG+PG PG    P   G  G  GE+GP G AG  
Sbjct: 1075 GNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRD 1134

Query: 887  ------GVPGPPGPPGLPG 899
                  G+PGP GP G PG
Sbjct: 1135 GLQGPVGLPGPAGPVGPPG 1153



 Score =  477 bits (1228), Expect = e-134
 Identities = 317/780 (40%), Positives = 366/780 (46%), Gaps = 153/780 (19%)

Query: 260  TPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG----- 314
            TPS   D     GE+ P  P  P     I     D      P PP   G     G     
Sbjct: 348  TPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEE 407

Query: 315  ------------------APGK--PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGF 354
                              +P +  PG P A+  T  +G  G  G KGQKGEP +      
Sbjct: 408  TIRNLDENYYDPYYDPTSSPSEIGPGMP-ANQDTIYEGIGGPRGEKGQKGEPAIIE---- 462

Query: 355  PGRGIPGPPGPPGTAGLPGELGRVGP---VGDPGRRGPPGPP------GPPGPRGTI--- 402
            PG  I GPPGP G AGLPG  G +GP   VGDPG RGPPG P      G PGP GT+   
Sbjct: 463  PGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLML 522

Query: 403  -----GFHDGDPLCP----------------------NACPPGRSGYPGLPGMRGHKGAK 435
                 G  D     P                       A P G +G PG  G  G  G K
Sbjct: 523  PFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLK 582

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGL------- 488
            GE G+ G QG +G +G  G  G+ G +G  G+ G RG+ G  G KG++G  GL       
Sbjct: 583  GEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEK 642

Query: 489  --DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
               G+PGP G PG PGD G+RG  GE GP+G  G  G RG+ G  GP G  G PGV G D
Sbjct: 643  GHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMD 702

Query: 547  GIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS--- 603
            G PG  G  G  G+PGPPG  G  G  G+PG  GA G  GEKG  G PG PG  G     
Sbjct: 703  GQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPP 762

Query: 604  GKPGQQGPPGE------VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP 657
            G PG++GPPGE       GP+GP G PG RG  G  G  GL G  G  G  G PG  G  
Sbjct: 763  GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822

Query: 658  GLPGMKGDRGVVGEPGPKGEQGASGEEGEA------------GERGELGDIGLP------ 699
            G+   KGDRG +G PGP+GE G  G +G              GE+G+LG  GLP      
Sbjct: 823  GI---KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879

Query: 700  GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTD 759
            GPKGS G PG PG  G +G RG PG  GPRG  GP G +GE+G  G+ G  GP G +  D
Sbjct: 880  GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGD 939

Query: 760  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 819
                                  +R  +G  G  G PGP GPPGPPG++G PG  G RG  
Sbjct: 940  ---------------GPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGET 984

Query: 820  GIK------GPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLP---------GDPG 864
            G +      GPPG +G +GP G+ G  GERG P  GP G PG  GLP         GDPG
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHP--GPPGPPGEQGLPGLAGKEGTKGDPG 1042

Query: 865  PASY-GRNGRDGERGPPGVAGIP------------GVPGPPGPPGLPGFCEPASCTMQAG 911
            PA   G++G  G RG PG  G+P            G PGPPGP G PG   PA      G
Sbjct: 1043 PAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102



 Score =  233 bits (594), Expect = 6e-61
 Identities = 135/287 (47%), Positives = 148/287 (51%), Gaps = 20/287 (6%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314
            LP    P     ERG  GE GP G  GPPG  G  G DG +G  GP G PG  G PG+PG
Sbjct: 1295 LPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354

Query: 315  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE 374
              G+ G PG     G DG PG  GS G  GEPG  G  G   RG PGP GP G  G  G 
Sbjct: 1355 PAGQDGPPGD---KGDDGEPGQTGSPGPTGEPGPSGPPG--KRGPPGPAGPEGRQGEKGA 1409

Query: 375  LGRVGPVGDPGRRGPPGP---PGPPGPRGTIGF-----HDGDPLCPNA-CPPGRSGYPGL 425
             G  G  G PG+ GP GP   PG PGP G  G        G P  P    PPG  G PGL
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGL 1469

Query: 426  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
            PG++G  G KGE G PG  G  G  G+QGE G+ G  GP G+ G +G  GI G  G    
Sbjct: 1470 PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP--- 1526

Query: 486  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532
                G PGP GLPG PG +G +G  G  GPKG+ G  G  G PG PG
Sbjct: 1527 ---IGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPG 1570



 Score =  223 bits (567), Expect = 8e-58
 Identities = 153/375 (40%), Positives = 174/375 (46%), Gaps = 56/375 (14%)

Query: 576 PGIPGAK-----GVAGEKGSTGAPGKPGQMGNSGKPGQ--QGPPGEVGPRGPQGLPGSRG 628
           PG+P  +     G+ G +G  G  G+P  +    +PG   +GPPG   P GP GLPG  G
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAII----EPGMLIEGPPG---PEGPAGLPGPPG 484

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPG---LPGPPG----LPGMKGDRGVVGEPGPKG----- 676
            +GP G  G PG+ G  G PGLPG   LPGPPG    LP   G  G  G  GP       
Sbjct: 485 TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES 544

Query: 677 ------EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 730
                 +Q      G AG  G  G  G  GP GS G  GEPG  GP+G RG+ G  GP G
Sbjct: 545 QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG 604

Query: 731 PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 790
            PG RG  G  GA G+PG  GP G    D                   A L   + G  G
Sbjct: 605 KPGRRGRAGSDGARGMPGQTGPKGDRGFDG-----------------LAGLPG-EKGHRG 646

Query: 791 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-G 849
            PG  GPPGPPG  GE G  G++G RGLPG  GP G LG +GP G  G  G  G  G+ G
Sbjct: 647 DPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706

Query: 850 PNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP---PGPPGLPGFCEPASC 906
           P G  G  G PG PG    G  G  G  GP G  G PG  GP   PG PG+PG   P   
Sbjct: 707 PKGNVGPQGEPGPPG--QQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764

Query: 907 TMQAGQRAFNKGPDP 921
             + G      G  P
Sbjct: 765 PGKEGPPGEKGGQGP 779



 Score =  121 bits (304), Expect = 3e-27
 Identities = 65/154 (42%), Positives = 76/154 (49%), Gaps = 14/154 (9%)

Query: 244  PLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP 303
            P +P  +    +P  +         GP G  GP GPP   G+PG+ G  G +G KG PG 
Sbjct: 1431 PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPP---GLPGLKGDSGPKGEKGHPGL 1487

Query: 304  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 363
             G  G PG+ G  G  G PG  G +GP G  G  G  G  G PG P        G+PGPP
Sbjct: 1488 IGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPP--------GLPGPP 1539

Query: 364  GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG 397
            GP G     G  G  GP G+ G  GPPGPPGPPG
Sbjct: 1540 GPKGA---KGSSGPTGPKGEAGHPGPPGPPGPPG 1570


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  530 bits (1364), Expect = e-150
 Identities = 339/794 (42%), Positives = 391/794 (49%), Gaps = 157/794 (19%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD--- 325
            GPPG +G  G PGPPG+PG+ GI G RGP+GPPGP G  G PG PGA G+ G PG     
Sbjct: 625  GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684

Query: 326  ---------GLTGPDGSPGSIGSKGQKGEPGV---------------PGSRGFPGR-GIP 360
                     GL G  G+PG  G KG KG PG                PG++G+PGR G+P
Sbjct: 685  AHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLP 744

Query: 361  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 420
            GP G PG  G  G +G  G  G PG  G  G PG PG RG +G      +     PPG  
Sbjct: 745  GPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLD 804

Query: 421  GYP------------------------GLPGMRGHKGAKGEIGEPGRQGHKGEE------ 450
            G P                        G PG +G KG  G +GEPG +G KGE+      
Sbjct: 805  GNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVS 864

Query: 451  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP------------ 498
            GD G  G+ G+QG PG  G RG  G +G  G+KG+ G  G PGP+G P            
Sbjct: 865  GDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPE 924

Query: 499  ---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 555
               G PG +G  GP G+ GP+GD G  G  G PGL G  G  G PG  G DG+ G PG  
Sbjct: 925  GMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP 984

Query: 556  GEPGKPGPPGDAGLQGLPGVPGIPGAK---------GVAGEKGSTGAPGKPGQMGNSGKP 606
            G PG  G  G  G  GL G PGI G K         GV G KGS G PG PG MG  G+P
Sbjct: 985  GRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEP 1044

Query: 607  GQQGPPGEVGP---------RGPQGLPGSRGEL---------GPVGSPGLP------GKL 642
            G QGPPG  GP         RGP+G  G  GE          GP G PG P      G+ 
Sbjct: 1045 GPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104

Query: 643  GSLGSPGLPGLPGP---------PGLPGMKGDRGVVGEP---GPKGEQGASGE---EGEA 687
            G LGS G PG+PGP         PG PG +G +G +G P   GPKG  GA GE    GEA
Sbjct: 1105 GHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEA 1164

Query: 688  GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 747
            G +G+LG +G PG +G  G  GEPGL G  G  G  G++G RG PGP G  GE+G  GL 
Sbjct: 1165 GMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLM 1224

Query: 748  GVQGPPG-------RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 800
            G  GPPG       R P  +  KQ      +       A   +   G  G+PG PGPPG 
Sbjct: 1225 GEDGPPGPPGVTGVRGPEGKSGKQ----GEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280

Query: 801  PGPPGE------NGFPGQMGIRGLPGI------KGPPGALGLRGPKGDLGEKGE----RG 844
            PGP G        G PG+MG +G PG+      KG  G LG  GPKG+ GE+GE     G
Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEG 1340

Query: 845  PPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP---PGPPGL 897
            PPG    RGP G  G  G PGDPG    G+ G  G RG PG  G PG PGP   PGP G 
Sbjct: 1341 PPGPPGDRGPVGDRGDRGEPGDPGYP--GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGS 1398

Query: 898  PGFCEPASCTMQAG 911
             G   P     +AG
Sbjct: 1399 KGAEGPKGKQGKAG 1412



 Score =  513 bits (1322), Expect = e-145
 Identities = 315/725 (43%), Positives = 370/725 (51%), Gaps = 106/725 (14%)

Query: 267  ERGPPGEQGPPGP---PGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 323
            ERGPPG  G PG    PGPPGVPG+ G  G  GP G PGP G  G  G  G PG  G  G
Sbjct: 797  ERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKG 856

Query: 324  ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELG 376
              G+ G  G PG  G KG +G PG PG+RG PG       +G  G PGPPG  G PG++G
Sbjct: 857  EQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG 916

Query: 377  RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 436
              G  G  G +G PG  G PGPRG +G  +GD         G  G PG PG+ G  G KG
Sbjct: 917  PPGDNGPEGMKGKPGARGLPGPRGQLG-PEGDE--------GPMGPPGAPGLEGQPGRKG 967

Query: 437  EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 496
              G PG  G KGE GD G  G VG QG  G  GL G  GIVG+KG++G  G  G PGP+G
Sbjct: 968  FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG 1027

Query: 497  L---PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPG 553
                PG PG  G  G PG  GP G RG  G RG  G  GP+G  G  G  G  G+ G PG
Sbjct: 1028 SMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPG 1087

Query: 554  TKGEPGKPGPPGDAGLQG---LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 610
             +G PG+PG  G AG +G     G PGIPG  G  G KG  G PG  G  G  G PG+ G
Sbjct: 1088 PQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMG 1147

Query: 611  PPGEVGPRGPQGLPGS---RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 667
            P G  G  G  GLPG    +G+LGP+G+PG  G +G  G PGL G  GP G  G+KGDR 
Sbjct: 1148 PKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR- 1206

Query: 668  VVGEPGPKGEQGASGEEGEAGERGELGD---IGLPGPKGSAGNPGEPGLRGPEGSR---- 720
              G+PGP GE G  G+EG  GE G  G     G+ GP+G +G  GE G  G +G++    
Sbjct: 1207 --GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQG 1264

Query: 721  -----GLPGVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVCMRVIQE 772
                 G+PG  GP G PGP+G +G  G TG P   G QG PG A  D H      + I  
Sbjct: 1265 QLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH------KGIVG 1318

Query: 773  HFAEMAASLKRPDSGATG-LPGRPGPPGPPGP---------PGENGFPGQMGIRGL---- 818
                     ++ + G  G   G PGPPG  GP         PG+ G+PGQ G++GL    
Sbjct: 1319 PLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP 1378

Query: 819  --------PGIKGPPGALGLRGPKGDLGEKGERGPPGR----------GPNGLPGAIGLP 860
                    PG +G PG  G +G +G  G++G+ G PGR          GP G+ G  GL 
Sbjct: 1379 GQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLE 1438

Query: 861  GDPGP----------ASYGRNGRDGERGP---------PGVAGIPGVPGPP---GPPGLP 898
            G  GP             G  G DG+ GP         PGVAG+PG  GPP   G  GLP
Sbjct: 1439 GIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLP 1498

Query: 899  GFCEP 903
            G   P
Sbjct: 1499 GQLGP 1503



 Score =  505 bits (1300), Expect = e-143
 Identities = 300/670 (44%), Positives = 350/670 (52%), Gaps = 65/670 (9%)

Query: 268  RGPPGEQGPPGPPGPPGV---------PGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 318
            +G PG+ G PGP G  G          PGI G  GDRG  GPPG PGP G  G PG PG 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 319  PGTPGADGLTGPDGS---PGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE 374
             GTPG  G  GP GS   PG  G+KG++G  G  G  G  G RG+ GPPGP G  G PG+
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 375  LGRVG---------------PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGR 419
             G  G               P G PG +G PG PGP GP+G IG      + P   PPG 
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIG--PPGEMGPKG-PPGA 1154

Query: 420  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 479
             G PGLPG  G KG  G +G PG QG  G+ G+ G  G+ G  GP G +G RG  G  G+
Sbjct: 1155 VGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGE 1214

Query: 480  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 539
             GEKG  GL GE GP   PG PG  G RGP G++G +G++G  GA+G  G  G  G+ G+
Sbjct: 1215 HGEKGQEGLMGEDGP---PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271

Query: 540  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599
            PG  G  G PG  G++G  G  G PG  G QG PG+ G  G KG+ G  G  G  G+ G+
Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331

Query: 600  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 659
             G  GK   +GPPG  G RGP G  G RGE G  G PG  G  G  G PG  G PG PG 
Sbjct: 1332 QGEDGKA--EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389

Query: 660  PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG- 718
             G  G +G  G  GPKG+QG +G  G    RG  G  GLPGP+G  G  G  G+ GP+G 
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGR---RGVQGLQGLPGPRGVVGRQGLEGIAGPDGL 1446

Query: 719  --------SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 770
                     +G  G +G  GP GP G +G  G  GLPG QGPPG             +  
Sbjct: 1447 PGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPG------------FKGE 1494

Query: 771  QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 830
                 ++    KR   G TGLPG  G PG  G PG++G  G  G+ GL G KGPPG +G 
Sbjct: 1495 SGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF 1554

Query: 831  RGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGV 888
            +G +G  G  G  G  G  GP G+ G  GLPG  G   S G  G  G RGPPG  G PG 
Sbjct: 1555 KGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPG- 1613

Query: 889  PGPPGPPGLP 898
              PPGPPG P
Sbjct: 1614 --PPGPPGGP 1621



 Score =  499 bits (1286), Expect = e-141
 Identities = 299/702 (42%), Positives = 354/702 (50%), Gaps = 98/702 (13%)

Query: 269  GPPGEQGPPGPPGPPGV---------PGIDGIDGDRGPKGPPGPPGPAGEP--------- 310
            GP G++GP GPPG PG+         PG  G+DG +G  G PG PGP GE          
Sbjct: 943  GPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLV 1002

Query: 311  GKPGAPGK---------PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----- 356
            G+PG  G+         PG PG  G  G  G PG +G+ G+ G  G PGSRG PG     
Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062

Query: 357  -----------------RGIPGPPGPPGTAGLPGELGRV---------------GPVGDP 384
                             RG+ GPPGP G  G PG+ G                 GP G P
Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122

Query: 385  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ 444
            G +G PG PGP GP+G IG      + P   PPG  G PGLPG  G KG  G +G PG Q
Sbjct: 1123 GTKGLPGEPGPQGPQGPIG--PPGEMGPKG-PPGAVGEPGLPGEAGMKGDLGPLGTPGEQ 1179

Query: 445  GHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ 504
            G  G+ G+ G  G+ G  GP G +G RG  G  G+ GEKG  GL GE GP   PG PG  
Sbjct: 1180 GLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGP---PGPPGVT 1236

Query: 505  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 564
            G RGP G++G +G++G  GA+G  G  G  G+ G+PG  G  G PG  G++G  G  G P
Sbjct: 1237 GVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAP 1296

Query: 565  GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 624
            G  G QG PG+ G  G KG+ G  G  G  G+ G+ G  GK   +GPPG  G RGP G  
Sbjct: 1297 GRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK--AEGPPGPPGDRGPVGDR 1354

Query: 625  GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 684
            G RGE G  G PG  G  G  G PG  G PG PG  G  G +G  G  GPKG+Q   G+ 
Sbjct: 1355 GDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQ---GKA 1411

Query: 685  GEAGERGELGDIGLPGPKGSAGNPGEPGLRGPE---------GSRGLPGVEGPRGPPGPR 735
            G  G RG  G  GLPGP+G  G  G  G+ GP+         G +G  G +G  GP GP 
Sbjct: 1412 GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPA 1471

Query: 736  GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP 795
            G +G  G  GLPG QGPPG             +       ++    KR   G TGLPG  
Sbjct: 1472 GKRGNPGVAGLPGAQGPPG------------FKGESGLPGQLGPPGKRGTEGRTGLPGNQ 1519

Query: 796  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854
            G PG  G PG++G  G  G+ GL G KGPPG +G +G +G  G  G  G  G  GP G+ 
Sbjct: 1520 GEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGIL 1579

Query: 855  GAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895
            G  GLPG  G   S G  G  G RGPPG  G PG PGPPG P
Sbjct: 1580 GPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGP 1621



 Score =  483 bits (1242), Expect = e-136
 Identities = 283/665 (42%), Positives = 346/665 (52%), Gaps = 46/665 (6%)

Query: 269  GPPGEQGPPGPPGPPGVPGI---------DGIDGDRGPKGPP---GPPGPAGEPGKPGAP 316
            GPPG+ GP G  G PG  G+         +G +G  GP G P   G PG  G PG+PG  
Sbjct: 916  GPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLD 975

Query: 317  GKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGEL 375
            G  G PG  G  GP G  G +G  G  GEPG+ G +G  G  G PG PGP G+ G PG  
Sbjct: 976  GVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMP 1035

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G +G  G+PG +GPPG  GPPG RG  G            P G  G  G  G RG KG  
Sbjct: 1036 GGMGTPGEPGPQGPPGSRGPPGMRGAKG---------RRGPRGPDGPAGEQGSRGLKGPP 1086

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
            G  G PGR G +G  G++G LG  G  G PG  G  G  G+ G+ G +G +G  G PG  
Sbjct: 1087 GPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEM 1146

Query: 496  GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 555
            G  G PG  G+ G PGEAG KGD G  G  G  GL G +G+ GL G  G  G  G+ G +
Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR 1206

Query: 556  GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G+PG  G  G+ G +GL G  G PG  GV G +G  G  GK G+ G +G  G +G  G++
Sbjct: 1207 GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQL 1266

Query: 616  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVV---GEP 672
            G  G  G PG  G  GP GS    G LG  G+PG  G  G PGL G  G +G+V   G P
Sbjct: 1267 GEMGVPGDPGPPGTPGPKGS---RGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPP 1323

Query: 673  GPKGEQGASGEEGEA----GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728
            GPKGE+G  GE+G+A    G  G+ G +G  G +G  G+PG PG  G +G RG PG +G 
Sbjct: 1324 GPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383

Query: 729  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788
             G PGPRG  G +G+ G  G +G  G+A          ++ +      +        +G 
Sbjct: 1384 PGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGP 1443

Query: 789  TGLPGRPGPPGPPGPPGENGFPGQM---------GIRGLPGIKGPPGALGLRGPKGDLGE 839
             GLPGR G  G  G  G++G PG M         G+ GLPG +GPPG  G  G  G LG 
Sbjct: 1444 DGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGP 1503

Query: 840  KGERGPPGR----GPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPPGP 894
             G+RG  GR    G  G PG+ G PGD G   + G  G  G +GPPG  G  G+ GP GP
Sbjct: 1504 PGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGP 1563

Query: 895  PGLPG 899
            PGL G
Sbjct: 1564 PGLMG 1568



 Score =  463 bits (1191), Expect = e-130
 Identities = 292/662 (44%), Positives = 333/662 (50%), Gaps = 80/662 (12%)

Query: 307  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG-- 364
            AG    P   G PG  G  GL GP G PG  G  G +G  G PG  G P  G+PGPPG  
Sbjct: 615  AGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNP--GLPGPPGAK 672

Query: 365  --------PPGTA--------GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD 408
                     PG A        GLPG  G  GP G  G +G PGP G PG +G  G  +G 
Sbjct: 673  GQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPG-PEGS 731

Query: 409  PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 468
            P       PGR G PG  G  G KG++G IG PG  G  G +G++      G  G PG +
Sbjct: 732  PGAKGY--PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGER------GLPGVPGKR 783

Query: 469  GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP------GDQGQRGPPGEAGPKGDRGAE 522
            G  G+ G  G  GE+G  GLDG PG  GLPG P      GD G  GP G  GPKG +G  
Sbjct: 784  GKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLM 843

Query: 523  GARGIPGLPGPKGDTGLPGVD---------GRDGIPGMPGTKGEPGKPGPPGDAGLQGLP 573
            G+ G PGL G KG+ G+PGV          G  G+PG PG +G+PG  G  GD G  G P
Sbjct: 844  GSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFP 903

Query: 574  GVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL 630
            G P   G PG  G  G+ G  G  GKPG  G  G  GQ GP G+ GP GP G PG  G+ 
Sbjct: 904  GPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQP 963

Query: 631  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 690
            G  G PG PG  G  G PG PG PGP G  G  G  G+VGEPG  GE+G  G  G  G  
Sbjct: 964  GRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVP 1023

Query: 691  GELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV------EGPRGPPGPRGVQGEQGAT 744
            G  G +G PG  G  G PGEPG +GP GSRG PG+       GPRGP GP G QG +G  
Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLK 1083

Query: 745  GLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPP 804
            G PG QG PGR P  Q +      +    F  +      P  G  GLPG PGP GP GP 
Sbjct: 1084 GPPGPQGRPGR-PGQQGVAGERGHLGSRGFPGIPGPSGPP--GTKGLPGEPGPQGPQGPI 1140

Query: 805  GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK---------GERGPPG----RGPN 851
            G    PG+MG +G PG  G PG  G  G KGDLG           G+RG PG     GP 
Sbjct: 1141 GP---PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM 1197

Query: 852  GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 911
            G  G  G  GDPGP        DGE G  G  G+ G  GPPGPPG+ G   P   + + G
Sbjct: 1198 GPDGLKGDRGDPGP--------DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249

Query: 912  QR 913
            ++
Sbjct: 1250 EK 1251



 Score =  428 bits (1100), Expect = e-119
 Identities = 266/611 (43%), Positives = 313/611 (51%), Gaps = 70/611 (11%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGK------PGAPGKP 319
            GPPG  GP G  G PG+PG  G  G+ GP+GPPG   PPG  G  G+       G  G+ 
Sbjct: 1018 GPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQ 1077

Query: 320  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE---LG 376
            G+ G  G  GP G PG  G +G  GE G  GSRGFPG  IPGP GPPGT GLPGE    G
Sbjct: 1078 GSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG--IPGPSGPPGTKGLPGEPGPQG 1135

Query: 377  RVGPVGDPGRRGPPGPPGP---PGPRGTIGFHDGDPLCPNACPP-----GRSGYPGLPG- 427
              GP+G PG  GP GPPG    PG  G  G   GD L P   P      G+ G PGL G 
Sbjct: 1136 PQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMK-GD-LGPLGTPGEQGLIGQRGEPGLEGD 1193

Query: 428  --MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
                G  G KG+ G+PG  G  GE+G +G +GE G  GPPG  G+RG  G  G +GEKG 
Sbjct: 1194 SGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGR 1253

Query: 486  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGR 545
             G  G  G QG  G  G  G  GPPG  GPKG RG+ G  G PG  G +G+ GL G DG 
Sbjct: 1254 TGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH 1313

Query: 546  DGI------PGMPGTKGEPGK-------PGPPGDAGL------QGLPGVPGIPGAKGVAG 586
             GI      PG  G KGE G+       PGPPGD G       +G PG PG PG +GV G
Sbjct: 1314 KGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQG 1373

Query: 587  EKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG 646
             +G  G  G+PG  G  G PG +G  G  GP+G QG  G+ G  G  G  GLPG  G +G
Sbjct: 1374 LRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433

Query: 647  SPGLPGLPGPPGLPG------MKGDRGVVGEPGPKGEQGASGEEGEAG------------ 688
              GL G+ GP GLPG       +G++G  G+PGP G  G  G  G AG            
Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKG 1493

Query: 689  ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG------PRGVQGEQG 742
            E G  G +G PG +G+ G  G PG +G  GS+G PG  G  G PG      P+G  G+ G
Sbjct: 1494 ESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIG 1553

Query: 743  ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802
              G+ G +GPPG    +  +  + +               R D G  G  G PGP G PG
Sbjct: 1554 FKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPG 1613

Query: 803  PPGENGFPGQM 813
            PPG  G P Q+
Sbjct: 1614 PPGPPGGPIQL 1624



 Score =  406 bits (1043), Expect = e-113
 Identities = 241/512 (47%), Positives = 279/512 (54%), Gaps = 49/512 (9%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGP---PGVPGIDGIDGDRGPKGPPGPPGPAGEPG 311
            LP    P       GPPGE GP GPPG    PG+PG  G+ GD GP G PG  G  G+ G
Sbjct: 1127 LPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRG 1186

Query: 312  KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAG 370
            +PG  G  G  G DGL G  G PG  G  G+KG+ G+ G  G PG  G+ G  GP G +G
Sbjct: 1187 EPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSG 1246

Query: 371  LPGELGRVGP---------VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP--GR 419
              GE GR G          +G+ G  G PGPPG PGP+G+ G      L P   P   G 
Sbjct: 1247 KQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRG-----SLGPTGAPGRMGA 1301

Query: 420  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 479
             G PGL G  GHKG  G +G PG +G KGE+G+ G+     A+GPPG  G RG  G  GD
Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGK-----AEGPPGPPGDRGPVGDRGD 1356

Query: 480  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAG---PKGDRGAEGARG------IPGL 530
            +GE G  G  G+ G QGL G PG QGQ G PG  G   PKG +GAEG +G       PG 
Sbjct: 1357 RGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGR 1416

Query: 531  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 590
             G +G  GLPG  G  G  G+ G  G  G PG  G AG QG  G  G PG  G AG++G+
Sbjct: 1417 RGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGN 1476

Query: 591  TG------APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 644
             G      A G PG  G SG PGQ GPPG+ G  G  GLPG++GE    GS G PG  G 
Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGE---PGSKGQPGDSGE 1533

Query: 645  LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 704
            +G PG+ GL GP G PG   D G  G  GP+G  G  G+EG  G  G LG  GLPGPKG 
Sbjct: 1534 MGFPGMAGLFGPKGPPG---DIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGD 1590

Query: 705  AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736
             G+ G+ GL+GP   RG PG  G  GPPGP G
Sbjct: 1591 KGSRGDWGLQGP---RGPPGPRGRPGPPGPPG 1619



 Score =  389 bits (998), Expect = e-108
 Identities = 264/693 (38%), Positives = 321/693 (46%), Gaps = 99/693 (14%)

Query: 260  TPSQTTDERGP----PGEQGPPGPPGPPGVPGIDGID-GDRGPKGPPGPP--GPAGEPGK 312
            TP  T   R P    P   G   P   P VP       G + P G       GP   P K
Sbjct: 494  TPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRK 553

Query: 313  PGAPGKPG-----TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPG 367
            P  P +PG      P +D  T P  SP     + Q  +   P     P + +   P P  
Sbjct: 554  P-VPLRPGKAARDVPLSDLTTRP--SP----RQPQPSQQTTPALVLAPAQFLSSSPRPTS 606

Query: 368  TAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPG 427
            +      L    P   P   GPPGP G  G  G               PPG  G PG+PG
Sbjct: 607  SGYSIFHLAGSTPF--PLLMGPPGPKGDCGLPG---------------PPGLPGLPGIPG 649

Query: 428  MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 487
             RG +G  G  G PG  G  G +G +G+ G    +   GA+G  G+ G+ G+ G  G +G
Sbjct: 650  ARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKG 709

Query: 488  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 547
              G PGP G    PG+QGQ GP G  G KG  G +G  G  G PGPKG  G  G+ G   
Sbjct: 710  HKGYPGPAG---HPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPG--- 763

Query: 548  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 607
            + G+PG+ GE G PG PG  G  G+PG PG      V GE+G  G  G PG++G  G PG
Sbjct: 764  LFGLPGSDGERGLPGVPGKRGKMGMPGFPG------VFGERGPPGLDGNPGELGLPGPPG 817

Query: 608  QQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 667
              G  G++G  GP G PG +G  G +GS G PG  G  G  G+PG+ G PG  G KG +G
Sbjct: 818  VPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQG 877

Query: 668  VVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 727
            + G PG +G+ G  G+    G++G +G  G PGP+G  G+ G PG  GPEG +G PG  G
Sbjct: 878  LPGFPGARGKPGPLGK---VGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARG 934

Query: 728  ---PRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
               PRG  GP G +G  G  G PG++G PGR                           RP
Sbjct: 935  LPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPG----------------------RP 972

Query: 785  DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG 844
              G  G+ G PG PG PGP GE GF G +G+ G PGI G  G  G+ GP G  G KG  G
Sbjct: 973  --GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMG 1030

Query: 845  PPGRGPNGLPGAIGLPGDPGPAS----------YGRNGRDGERGPPGVAG------IPGV 888
             PG     +PG +G PG+PGP             G  GR G RGP G AG      + G 
Sbjct: 1031 HPG-----MPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGP 1085

Query: 889  PGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
            PGP G PG PG    A      G R F   P P
Sbjct: 1086 PGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGP 1118



 Score = 90.1 bits (222), Expect = 8e-18
 Identities = 111/376 (29%), Positives = 135/376 (35%), Gaps = 97/376 (25%)

Query: 549 PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 608
           PGMP       +P PP    L         P       E   T    KP     S     
Sbjct: 430 PGMP-------RPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTST---H 479

Query: 609 QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGV 668
           + PP       P   PGS     P  +  +P   G+      P +P P   P        
Sbjct: 480 KPPPFTALSSSPAPTPGSTRSTRPPATM-VPPTSGTSTPRTAPAVPTPGSAP-------- 530

Query: 669 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728
            G   P G         EA ++         GPK S   P    LR  + +R +P +   
Sbjct: 531 TGSKKPIGS--------EASKKA--------GPKSSPRKPVP--LRPGKAARDVP-LSDL 571

Query: 729 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788
              P PR  Q  Q  T  P +   P                     A+  +S  RP S  
Sbjct: 572 TTRPSPRQPQPSQQTT--PALVLAP---------------------AQFLSSSPRPTSSG 608

Query: 789 ------TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK-------- 834
                  G    P   GPPGP G+ G PG  G+ GLPGI   PGA   RGP+        
Sbjct: 609 YSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGI---PGA---RGPRGPPGPYGN 662

Query: 835 ----GDLGEKGERGPPGRGP----NGLPGAIGLP---GDPGPASYGRNGRDGERGPPGVA 883
               G  G KG++G PG  P    +G  G +GLP   G+PGP      GR G +G PG A
Sbjct: 663 PGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPP-----GRKGHKGYPGPA 717

Query: 884 GIPGVPGPPGPPGLPG 899
           G PG  G PGP G PG
Sbjct: 718 GHPGEQGQPGPEGSPG 733


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  523 bits (1348), Expect = e-148
 Identities = 324/752 (43%), Positives = 373/752 (49%), Gaps = 157/752 (20%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDG-------------IDGDRGPKGPPGPPGPAGEPGKPGA 315
            GPPG+QGPPG PG PG  G  G             IDG RGP GP GPPG  G PG+PGA
Sbjct: 437  GPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGA 496

Query: 316  PGKPGTPGADGLTG---PDGSPGSIGS----------------KGQKGEPGVPGSRGFPG 356
             G  G PG DG+ G   P G+PG IG                 KG KG+PG PG  G  G
Sbjct: 497  KGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTG 556

Query: 357  R----------GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG--PRGTIGF 404
            R          G+PGP G PG+ GL GE G  G VG PG RG  GPPGPPG  P G IG 
Sbjct: 557  RAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGD 616

Query: 405  HD-----------------GDP--LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 445
                               G+P  + P   PPG  G PG PG  G +G +G  G PGR G
Sbjct: 617  KGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676

Query: 446  HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQG 505
              GE+G  G+ G +G  GPPG +G+ G+ G      + G  G  G PG  GLPG PG QG
Sbjct: 677  LPGEKGAVGQPG-IGFPGPPGPKGVDGLPG------DMGPPGTPGRPGFNGLPGNPGVQG 729

Query: 506  QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 565
            Q+G PG  G  G +G  G  GIPG PG KG  G+PGV G  G  G PG +G  G+PGPPG
Sbjct: 730  QKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPG 788

Query: 566  DAGLQGLPGVPGI--PGAKGVAGEKGSTGAPGKPGQMGNSGKPG--------------QQ 609
              G  G PGVPGI  PGA+G  G +G  G  G PG  G  G PG               Q
Sbjct: 789  LPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQ 848

Query: 610  GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---PGLPGMKGDR 666
            G PG  G  G  GLPG +G  G  G PG  G++G +G+PG PG PGP   PGLPG KGD 
Sbjct: 849  GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDH 908

Query: 667  GVVGEPGPKGEQGASGEEGEAG---------------------ERGELGDIGLPGPKGSA 705
            G  G  GP+G+ G  G++G+ G                     ++GE G IG  G KGS 
Sbjct: 909  GFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSR 968

Query: 706  GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 765
            G+PG PG+ G +G  G PG  GP+G PG   + G  GA GLPG +G  G           
Sbjct: 969  GDPGTPGVPGKDGQAGQPGQPGPKGDPG---ISGTPGAPGLPGPKGSVG----------- 1014

Query: 766  CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP 825
                                 G  G PG  G PG PGP G  G PG  G +G  G  GPP
Sbjct: 1015 -------------------GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPP 1055

Query: 826  GA--LGLRGPKGDLGEKGERGPPGR-------GPNGLPGAIGLPGDPG----PASYGRNG 872
            G    GLRG KGD G  G  G PG        G  G+PG+ GL G PG    P S G  G
Sbjct: 1056 GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPG 1115

Query: 873  RDGERGPPGVAGIPGVPGPPGPPGLPGFCEPA 904
              G++G PG+ GIPGV G  G PG PG   PA
Sbjct: 1116 EKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA 1147



 Score =  520 bits (1339), Expect = e-147
 Identities = 315/718 (43%), Positives = 368/718 (51%), Gaps = 126/718 (17%)

Query: 267  ERGPPG---------EQGPPGPPG--PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK--- 312
            ERGPPG         + GPPGPPG  P G  G  G  G  G  G PG PGP GEPGK   
Sbjct: 584  ERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVP 643

Query: 313  -PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 371
             PG PG  G PG+ G  GP G  G  G+ G+ G PG  G+ G PG G PGPPGP G  GL
Sbjct: 644  LPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL 703

Query: 372  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGH 431
            PG++G  G  G PG  G PG PG  G +G           P    PG  G PGLPG+ G 
Sbjct: 704  PGDMGPPGTPGRPGFNGLPGNPGVQGQKGE----------PGVGLPGLKGLPGLPGIPGT 753

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE 491
             G KG IG PG  G  G  G  G  G  G  GPPG  G  G  G+ G  G  GARG  G 
Sbjct: 754  PGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGG 812

Query: 492  PGPQGLPGAPGDQGQRGPPG-----EAGPKGDRGAEGARGI------PGLPGPKGDTGLP 540
             GP GL G PG +G++G PG       GPKGD+GA+G  GI      PGLPG +G  G+P
Sbjct: 813  QGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIP 872

Query: 541  GVDGRDGIPGMPGTKGEPGKPGP------PGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 594
            G  G  G  G+ GT G+PG PGP      PG+ G  G PG  G  G  G+ G+KG  G P
Sbjct: 873  GFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLP 932

Query: 595  GKPGQM------------GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 642
            GKPG M            G+ G+ GQ GP GE G RG  G PG  G+ G  G PG PG  
Sbjct: 933  GKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPK 992

Query: 643  GS---LGSPGLPGLPGPPG------LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 693
            G     G+PG PGLPGP G      LPG  G++GV G PGP+G  G  G++G  GE+G+ 
Sbjct: 993  GDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQA 1052

Query: 694  G--DIGLPGPKGS------AGNPGEPGLRGPEGSRGLPGVEGPR---------GPPGPRG 736
            G   IG+PG +G       AG PG PG +G +GS G+PG+ G           G PG  G
Sbjct: 1053 GPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPG 1112

Query: 737  VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 796
            + GE+G  GLPG+ G PG                                G  GLPG PG
Sbjct: 1113 LPGEKGDKGLPGLDGIPG------------------------------VKGEAGLPGTPG 1142

Query: 797  PPGP---PGPPGENGFPGQMGIRGLPGIKGP-----PGALGLRGPKGDLGEKGERGPPG- 847
            P GP    G PG +G PG  G +G PG+ G      PGA G +G KG++G  G  G PG 
Sbjct: 1143 PTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGI 1202

Query: 848  ------RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
                  +G  G PG  G PG PG   +   G  G+RGP G  G+PG+PGP GPPGLPG
Sbjct: 1203 PGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPG 1260



 Score =  519 bits (1337), Expect = e-147
 Identities = 327/791 (41%), Positives = 381/791 (48%), Gaps = 162/791 (20%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            GP G++G PG PG PG+PG  G  G  G  G PGPPGP G  G PG  G PGTPG  G  
Sbjct: 661  GPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFN 719

Query: 329  GPDGSPGSIGSKGQKGEPGV--PGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPG 385
            G  G+PG    +GQKGEPGV  PG +G PG  GIPG PG  G+ G+PG  G  G +G PG
Sbjct: 720  GLPGNPGV---QGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPG 776

Query: 386  RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG---LPGMRGHKGAKGEIG--- 439
             +G  G PGPPG  G++G     P  P   PPG  G PG    PG+ G  G KGE G   
Sbjct: 777  LQGIRGEPGPPGLPGSVG----SPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG 832

Query: 440  -----EPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPG- 493
                  PG +G KG +G  G  G+ G  G PG QG  GI G  G KGE G  G  G+PG 
Sbjct: 833  FPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS 892

Query: 494  --PQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG------------------- 532
              P G PG PG++G  G PG +GP+GD G +G +G  GLPG                   
Sbjct: 893  PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGD 952

Query: 533  --------PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKG- 583
                    P G+ G  G  G  G+PG  G  G+PG+PGP GD G+ G PG PG+PG KG 
Sbjct: 953  QGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012

Query: 584  -----VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL--------------- 623
                 + G  G  G PG PG  G+ G PG +G  GE G  GP G+               
Sbjct: 1013 VGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIA 1072

Query: 624  -----PGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE---PGPK 675
                 PG +GE G +G PG+PG  G  GSPG  G PG PGLPG KGD+G+ G    PG K
Sbjct: 1073 GFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVK 1132

Query: 676  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPG 724
            GE G  G  G  G  G+ G+ G  G  GSAG  GEPGL           +G +GS+G  G
Sbjct: 1133 GEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVG 1192

Query: 725  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
              G  G PG  G +GEQG  G PG QG PG   +  H             A       R 
Sbjct: 1193 FPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGH-------------ATEGPKGDRG 1239

Query: 785  DSGATGLPGRPGPPGPPGPPG------ENGFPGQMGIRGLPGIKGPPGALGLRGPKGD-- 836
              G  GLPG PGP GPPG PG      + G PG  G  G+PG KG PG  G+ G  G   
Sbjct: 1240 PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG 1299

Query: 837  -LGEKGERGPPG-------------------RGPNGLPGAIGLPGDPGPAS-----YGRN 871
              G KG+ GPPG                   +G  G+PGA GLPG PGP        G  
Sbjct: 1300 ITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP 1359

Query: 872  GRDGERGPPGVAGIPGVPGP---------------------PGPPGLPGFCEPASCTMQA 910
            G  G  GPPG+ G+ G+PGP                      G PG  G   PA  T   
Sbjct: 1360 GLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT--- 1416

Query: 911  GQRAFNKGPDP 921
            G R F   P P
Sbjct: 1417 GPRGFPGPPGP 1427



 Score =  509 bits (1311), Expect = e-144
 Identities = 321/746 (43%), Positives = 379/746 (50%), Gaps = 113/746 (15%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP--------- 306
            P +  P     + G  GE+G PG PG PG PG+ G  G +G KG  GPPGP         
Sbjct: 280  PGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 307  ---AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIG--SKGQKGEPGVP------GSRGFP 355
                GE G PG PG  G PG  G  G  G PG  G    GQ G PG P      G RGFP
Sbjct: 340  LGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFP 399

Query: 356  GRGIPGP------PGPPGTAGLPGELGRVGPV-----GDPGRRGPPGPPGPPGPRGTIGF 404
            G  +PGP      PGPPG+ G PG+ G    +     G PG +GPPG PG PG  G IG 
Sbjct: 400  GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE 459

Query: 405  HDGDPLCPNAC-------PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE-- 455
                      C       PPG  G PG  G  G  GAKG+ G PGR G  G  G QG   
Sbjct: 460  KGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519

Query: 456  -LGEVGAQGPPGA-------------QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP 501
             +G+ GA+G PG               G  G  G+ G  G  G  G  G PGP+G PG+ 
Sbjct: 520  LIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSV 579

Query: 502  GDQGQRGPPGEAGPKGDRGAEGARGIPGL--PGPKGDTGLPGVDGRDGIPGMPGTKGEPG 559
            G +G+RGPPG  G  G RG  G  G PG    GP GD G  G  G  G PG+PG KGEPG
Sbjct: 580  GLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPG 639

Query: 560  KPGP-PGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 618
            K  P PG  G +GLPG PG PG +G  G  G+ G PG PG+ G  G+PG  G PG  GP+
Sbjct: 640  KIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG-IGFPGPPGPK 698

Query: 619  GPQGLPGSRGELGPVGSP---GLPGKLG--------SLGSPGLPGLPGPPGLPGMKGDRG 667
            G  GLPG  G  G  G P   GLPG  G         +G PGL GLPG PG+PG  G++G
Sbjct: 699  GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKG 758

Query: 668  VVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 727
             +G PG  GE GA G  G  G RGE G  GLP   GS G+PG PG+ GP G+RG PG +G
Sbjct: 759  SIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLP---GSVGSPGVPGI-GPPGARGPPGGQG 814

Query: 728  PRGPPGPRGVQGEQGATGLPGVQ--GPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP- 784
            P G  GP G++GE+G  G PG+   GP G    D+  + +     Q     +      P 
Sbjct: 815  PPGLSGPPGIKGEKGFPGFPGLDMPGPKG----DKGAQGLPGITGQSGLPGLPGQQGAPG 870

Query: 785  ---------DSGATGLPGRPGPPGP------PGPPGENGFPGQMGIRGLPGIKGPPGALG 829
                     + G  G PG+PG PGP      PG  G++GFPG  G RG PG+KG  G +G
Sbjct: 871  IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930

Query: 830  L---------------RGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGR 873
            L               +G KGD GEKG+ GP G +G  G PG  G+PG  G A  G+ G+
Sbjct: 931  LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA--GQPGQ 988

Query: 874  DGERGPPGVAGIPGVPGPPGPPGLPG 899
             G +G PG++G PG PG PGP G  G
Sbjct: 989  PGPKGDPGISGTPGAPGLPGPKGSVG 1014



 Score =  505 bits (1301), Expect = e-143
 Identities = 324/805 (40%), Positives = 384/805 (47%), Gaps = 200/805 (24%)

Query: 268 RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAPGKPGTPGA 324
           +GP G QGPPG  G  G PG+ G  G RGP G    PG PG  G PG+ G PG PG PG 
Sbjct: 66  QGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGC 125

Query: 325 DGLTG---PDGSPGSIGSKGQKGEPGVPGSRGFPG--------------RGIPGPPGPPG 367
           +G  G   P G PG  G  G  G PG+PG +G PG              RG PG PG PG
Sbjct: 126 NGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPG 185

Query: 368 TAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPG 427
             GLPG  G VGP G  G  GPPGPPGPPG +G +G     P        G SG PG+PG
Sbjct: 186 PPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKG-DQGVSGPPGVPG 244

Query: 428 M-----------RGHKGAK-----------GEIGEPGRQGHKGEEGDQGELGEVGAQGPP 465
                       +G KG K           GE GEPG+ G +G+ G  G+ GE G+ G P
Sbjct: 245 QAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFP 304

Query: 466 GAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR 525
           G  G  G+ G  G +GEKG  G  G PG     G  G++G+RG PG  GP+G+ G +G  
Sbjct: 305 GEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFP 364

Query: 526 GIPGLPGP--------------------KGD-----TGLPGVDGRDGIPGMPGTKGEPG- 559
           G+PG PGP                    KGD     T LPG  GRDG+PG PG+ G PG 
Sbjct: 365 GLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQ 424

Query: 560 ----------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST------------------ 591
                     +PGPPGD G  G+PG PG  G  G  G+KG +                  
Sbjct: 425 PGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGP 484

Query: 592 ----GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL---PGSRGELGPV----------- 633
               G PG+PG  G+ G PG+ G  G  GP+G  GL   PG++GE G             
Sbjct: 485 PGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKG 544

Query: 634 -----GSPGLPGKLGSLGSPGLPGLPGPPGLP---GMKGDRGV---VGEPGPKGEQGAS- 681
                G PG+ G+ GS G  G PGLPGP G P   G+KG+RG    VG PG +G+ G   
Sbjct: 545 DPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPG 604

Query: 682 ----------GEEGEAGERGELGDIGLPGPKGSAGN----PGEPGLRGPEGSRGLPGVEG 727
                     G++G+AG  G  G  GLPGPKG  G     PG PG  G  GS G PG +G
Sbjct: 605 PPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQG 664

Query: 728 PR---GPPGPRGVQGEQGATGLPGV--QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
            R   G PG  G+ GE+GA G PG+   GPPG                            
Sbjct: 665 DRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG---------------------------- 696

Query: 783 RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIR--------GLPGIKGPPGALGLRGPK 834
               G  GLPG  GPPG PG PG NG PG  G++        GLPG+KG PG  G+ G  
Sbjct: 697 --PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTP 754

Query: 835 GDL---------GEKGERGPPG-------RGPNGLPGAIGLPGDPGPASYGRNGRDGERG 878
           G+          GE G  GPPG        GP GLPG++G PG PG    G  G  G +G
Sbjct: 755 GEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQG 814

Query: 879 PPGVAGIPGVPGPPGPPGLPGFCEP 903
           PPG++G PG+ G  G PG PG   P
Sbjct: 815 PPGLSGPPGIKGEKGFPGFPGLDMP 839



 Score =  474 bits (1221), Expect = e-133
 Identities = 293/681 (43%), Positives = 341/681 (50%), Gaps = 132/681 (19%)

Query: 268  RGPPGEQGPPGPPGPPGV------PGIDGID-----GDRGPKGPPGPPGPAGEPGKPG-- 314
            RGPPG QGPPG  GPPG+      PG  G+D     GD+G +G PG  G +G PG PG  
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866

Query: 315  -APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG---FPG----RGIPGPPGPP 366
             APG PG PG+ G  G  G+PG  GS G  G PG+PG +G   FPG    RG PG  G  
Sbjct: 867  GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDK 926

Query: 367  GTAGLPG---------------------ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH 405
            G  GLPG                     E G++GP+G+ G RG PG PG PG  G  G  
Sbjct: 927  GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAG-Q 985

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG------------DQ 453
             G P  P    PG SG PG PG+ G KG+ G +G PG  G KG  G            D+
Sbjct: 986  PGQP-GPKG-DPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 454  GELGEVGAQGPPGA-----------QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 502
            G  GE G  GPPG            QG+ G  G  G+KGEKG+ G+ G PG  GL G+PG
Sbjct: 1044 GAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPG 1103

Query: 503  DQGQRGPPGEAGPKGDRGAEGARGIPGL---------PGPKGDTGLPGVDGRDGIPGMPG 553
              G  G PG  G KGD+G  G  GIPG+         PGP G  G  G  G DGIPG  G
Sbjct: 1104 SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163

Query: 554  TKGEPGKPG--------PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 605
             KGEPG PG          GD G +G  G PG+ G+ G+ G KG  G  G PG  G  G 
Sbjct: 1164 EKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGL 1223

Query: 606  PGQQG--PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 663
            PG  G    G  G RGPQG PG  G  GP+G PGLPG  G  G  G PG PG PG+PG K
Sbjct: 1224 PGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPK 1283

Query: 664  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 723
            GD      PG +G  G  G  G  G +G++G  G+PG +G  G PG  G++G +G +G+P
Sbjct: 1284 GD------PGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP 1337

Query: 724  GVEGPRGPPGPRGVQG-EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 782
            G +G  GPPGP G     +G  GLPG +GPP                             
Sbjct: 1338 GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP----------------------------- 1368

Query: 783  RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
                G  GL G PGP G  G  G  G PG  GI   PG  G PG  G  GP G  G +G 
Sbjct: 1369 ----GLKGLQGLPGPKGQQGVTGLVGIPGPPGI---PGFDGAPGQKGEMGPAGPTGPRGF 1421

Query: 843  RGPPGRGPNGLPGAIGLPGDP 863
             GPP  GP+GLPG++G PG P
Sbjct: 1422 PGPP--GPDGLPGSMGPPGTP 1440



 Score =  402 bits (1032), Expect = e-111
 Identities = 234/516 (45%), Positives = 267/516 (51%), Gaps = 68/516 (13%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---------P 319
            GP GE+G  G PG PGVPG DG  G  G  GP G PG +G PG PG PG          P
Sbjct: 960  GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLP 1019

Query: 320  GTPG---ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG 376
            GTPG     G+ GP GSPG  G KG KGE G  G  G    G+ G  G  G AG PG  G
Sbjct: 1020 GTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPG 1079

Query: 377  RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 436
              G  G  G  G PG PG  G  G++G+     L      PG  G  GLPG+ G  G KG
Sbjct: 1080 EKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL------PGEKGDKGLPGLDGIPGVKG 1133

Query: 437  EIGEPGRQG------HKGEEGDQGELGEVGAQGPPG--AQGLRGITGIVGDKGEKGARGL 488
            E G PG  G       KGE G  G  G  G +G PG   +G  G  G  GDKG KG  G 
Sbjct: 1134 EAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGF 1193

Query: 489  DGEPGPQGLPGAPGDQGQRGPPGEAG--------------PKGDRGAEGARGIPGLPGPK 534
             G  G  G+PG+ G+QG  GPPG  G              PKGDRG +G  G+PGLPGP 
Sbjct: 1194 PGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPM 1253

Query: 535  GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 594
            G  GLPG+DG  G  G PG  G PG PGP GD G QG+PG+ G P   G+ G KG  G P
Sbjct: 1254 GPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP---GITGSKGDMGPP 1310

Query: 595  GKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL-GSPGLPGL 653
            G PG  G  G PG QG  G+   +G QG+PG++G  GP   PG PG    + G PGLPG 
Sbjct: 1311 GVPGFQGPKGLPGLQGIKGD---QGDQGVPGAKGLPGP---PGPPGPYDIIKGEPGLPGP 1364

Query: 654  PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL 713
             GPPGL G++      G PGPKG+QG +G             +G+PGP G  G  G PG 
Sbjct: 1365 EGPPGLKGLQ------GLPGPKGQQGVTGL------------VGIPGPPGIPGFDGAPGQ 1406

Query: 714  RGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 749
            +G  G  G  G  G  GPPGP G+ G  G  G P V
Sbjct: 1407 KGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442



 Score =  367 bits (943), Expect = e-101
 Identities = 243/593 (40%), Positives = 290/593 (48%), Gaps = 103/593 (17%)

Query: 421 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG---ITGIV 477
           G  G  G RG  G +G IG PG QG +G +G  G+ G+ G  G PG +G RG    +G  
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 478 GDKGEKGARGLDGEPGPQGLPGAPGDQGQR---------------GPPGEAGPKGDRG-- 520
           G+ G  G  G DG PGP G+PG  G +G+R               GPPG  G KGD G  
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 521 --------AEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP-------- 564
                    +G RG PG+PG  G  GLPG+ G  G PG  G  G PG PGPP        
Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222

Query: 565 ------GDAGLQGLPGVPGIPG-----------AKGVAGEKGSTGAPGKP--GQMGNSGK 605
                 GD G QG+ G PG+PG            KG  G+KG  G  G P  G+ G  GK
Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK 282

Query: 606 PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP----- 660
           PG +G PG+ G +G +G PG  GE    G PGL G+ G  G  G  G PGPPG+      
Sbjct: 283 PGPRGKPGKDGDKGEKGSPGFPGE---PGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 661 -GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 719
            G KG+RG  G PGP+GE G  G  G  G+    G  GLP P G AG PG PG RG +G 
Sbjct: 340 LGEKGERGYPGTPGPRGEPGPKGFPGLPGQP---GPPGLPVP-GQAGAPGFPGERGEKGD 395

Query: 720 RGLPGV--------EGPRGPPGPRGVQGEQGAT--------GLPGVQGPPGRAPTDQHIK 763
           RG PG         +G  GPPG  G  G+ G T        G PG QGPPG       I 
Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 455

Query: 764 QVCMRVIQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGI 821
           ++  +  Q+  + +   +   R   G  G PG  G PG PG  G+ G PG+ G+ G+PG 
Sbjct: 456 EIGEKG-QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514

Query: 822 KGPPGALGLRGPKGDLGE-------KGERGPPG-------RGPNGLPGAIGLPGDPGP-A 866
           +G PG +G  G KG+ GE       KG++G PG        G  G PG  G PG PGP  
Sbjct: 515 QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG 574

Query: 867 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           S G  G  GERGPPG  G PG  G  GPPG PG+  PA      GQ  F  GP
Sbjct: 575 SPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGP 626



 Score =  186 bits (471), Expect = 1e-46
 Identities = 115/279 (41%), Positives = 134/279 (48%), Gaps = 50/279 (17%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P      +G PG  G PGP GPPG+PGIDG+ GD+         G  G PG PG PG  G
Sbjct: 1234 PKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDK---------GNPGWPGAPGVPGPKG 1284

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
             PG  G+ G  GSPG  GSKG  G PGVP        G  GP G PG  G+ G+    G 
Sbjct: 1285 DPGFQGMPGIGGSPGITGSKGDMGPPGVP--------GFQGPKGLPGLQGIKGD---QGD 1333

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN-ACPPGRSGYPGLPGMRGHKGAKGEIG 439
             G PG +G PGPPGPPGP   I    G+P  P    PPG  G  GLPG +G +G  G +G
Sbjct: 1334 QGVPGAKGLPGPPGPPGPYDII---KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390

Query: 440  EPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPG 499
             PG  G  G +G  G+ GE+G  GP                   G RG  G PGP GLPG
Sbjct: 1391 IPGPPGIPGFDGAPGQKGEMGPAGP------------------TGPRGFPGPPGPDGLPG 1432

Query: 500  APGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 538
            +       GPPG   P  D G    R    +  P+  +G
Sbjct: 1433 S------MGPPGT--PSVDHGFLVTRHSQTIDDPQCPSG 1463



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 48/109 (44%), Positives = 55/109 (50%), Gaps = 8/109 (7%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 327
            +G PG  GP GPPG  G+ G+ G  G +G  G  G PGP G PG  GAPG+ G  G  G 
Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415

Query: 328  TGPDGSPGSIGSKGQKGEPGVPGS----RGF----PGRGIPGPPGPPGT 368
            TGP G PG  G  G  G  G PG+     GF      + I  P  P GT
Sbjct: 1416 TGPRGFPGPPGPDGLPGSMGPPGTPSVDHGFLVTRHSQTIDDPQCPSGT 1464


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  523 bits (1348), Expect = e-148
 Identities = 308/711 (43%), Positives = 360/711 (50%), Gaps = 79/711 (11%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA---PGKPGTPGAD 325
            G PGE+G  G  G  G PG  G DG+RG +GPPGP G AGEPG  G     G PG  G  
Sbjct: 557  GLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRP 616

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPG------SRGFPGR----GIPGPPGPPGTAGLPGEL 375
            G+TG DG+PG+ G+ G  GEPG PG      S+G PG     G PG  GPPG  G+PG  
Sbjct: 617  GVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLP 676

Query: 376  GRVGPVGDPGRRGPPG------------PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 423
            G  GP+G PG  GP G            PPG PGPRG  G      L       G  G+P
Sbjct: 677  GSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFP 736

Query: 424  GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLR---GITGIVGDK 480
            G  G  G KG +G+ G PG +G  G EG +G+ G+ G +GPPG+ G +   G+ G+ G  
Sbjct: 737  GFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYP 796

Query: 481  GEKGARGLDGEPGPQGLPGAPGDQGQRGPP---GEAGPKGDRGAEGARGIPGLPGPKGDT 537
            G  G +G  G PGP G  G  G  G+ G P   GE GP G RG  G  G  G PGPKGD 
Sbjct: 797  GRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDV 856

Query: 538  GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKP 597
            G  G  G  G  G+PG +G PG PGP G  G QG  G PG PG +G  G +G TG PG  
Sbjct: 857  GQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916

Query: 598  GQMGNSGKP------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 651
            G +G  GK       G++GPPG  GP G QGLPG  G  G  G  G PG LG  G  GL 
Sbjct: 917  GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLR 976

Query: 652  GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 711
            G PGP G PG  G  G+ G+ GP G  GA+G  GE G  G  G IGLPG  GS G  G  
Sbjct: 977  GFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPA 1036

Query: 712  GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQ 771
            G +G  G RG PG  G  G PGP G  G  GA G  G +G  G      H          
Sbjct: 1037 GKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGH---------- 1086

Query: 772  EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQM------------GIRGLP 819
                   +   + D+G  G PG  GP G PGPPG +G  G+             G+RG  
Sbjct: 1087 -----KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV 1141

Query: 820  GIKGPPGALGLRGP---KGDLGEKGERGPPG----RGPNGLPGAIGLPGDPG----PASY 868
            G+ GPPG  GL GP   KG++G+ G  GP G    RGP G  G+ G PG PG    P + 
Sbjct: 1142 GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAV 1201

Query: 869  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
            G  G  G+ G PG  G PG+PGP G  G  G   P+      G+    KGP
Sbjct: 1202 GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK----KGP 1248



 Score =  518 bits (1335), Expect = e-147
 Identities = 301/673 (44%), Positives = 346/673 (51%), Gaps = 69/673 (10%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP---PGPAGEPGKPGAPGKPGTPGAD 325
            GP GE+G  G  G PG+ G  G  G RG +G PG    PGP G+ G+ GAPG PG  G  
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDP 384
            GL GP G PG  G  G +G+ G PG  G  G  G  G  GPPG AG+ G  G+ G VG  
Sbjct: 872  GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 385  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ 444
            G RGPPGPPGPPG +G  G    +       PPG  G  G  G+RG  G KG  G+PG  
Sbjct: 932  GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991

Query: 445  GHKGEEGDQGEL------GEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQ 495
            G KG++G  G +      GE G  GP G  GL G +G    VG  G+KG+RG  G PGP 
Sbjct: 992  GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPT 1051

Query: 496  GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 555
            G  G PG  G  GPPG AGP G+ G +G  G PG  G KGD       G  G PG PG +
Sbjct: 1052 GKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGD------KGDAGPPGQPGIR 1105

Query: 556  GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G  G PGPPG  G QG  G PG+ G KG  G +G  G  G PG  G  G PG++G  G+V
Sbjct: 1106 GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165

Query: 616  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL------------PGLPGPPGLPGMK 663
            G  GP G PG RG  GP GS G PG  G +G PG             PG PG PG+PG K
Sbjct: 1166 GSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225

Query: 664  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 723
            GD G  G+ GP G  G  G++G  GE G  G +G  G  G  G PG+PG+ G +GS G  
Sbjct: 1226 GDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285

Query: 724  GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 783
            G  G  G PGP G  GE GA G PG +GP G                      M    + 
Sbjct: 1286 GDPGDVGGPGPPGASGEPGAPGPPGKRGPSG---------------------HMGREGRE 1324

Query: 784  PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 843
             + GA G PG  GPPG  GP G  G PG++G  GL GI GP G  GL G  G +G  G  
Sbjct: 1325 GEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPL 1384

Query: 844  GPPG----------RGPNGLPGAIGLPGDPGPA-SYGRNGRDGERGPPGVAGIPGVPGP- 891
            GP G          +G  G  G IGL G PG A   G  G  G +GPPG  G PG PGP 
Sbjct: 1385 GPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPI 1444

Query: 892  -----PGPPGLPG 899
                 PGPPG+ G
Sbjct: 1445 GSLGHPGPPGVAG 1457



 Score =  510 bits (1313), Expect = e-144
 Identities = 317/737 (43%), Positives = 361/737 (48%), Gaps = 118/737 (16%)

Query: 261  PSQTTDERGP-PGEQGPPGPP----------GPPGVPGIDGIDGDRGPKGPPGPPGPAGE 309
            PS+T  +  P  GE+G  G P          GPPG PG  G+ G   P GPPGPPG  G+
Sbjct: 361  PSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG---PSGPPGPPGFPGD 417

Query: 310  PGKPGAPGKPGTPGADGLTGPDGS----PGSIGSKGQKGEP------------------- 346
            PG PG  G PG PG DG+ GP G+    P        KG P                   
Sbjct: 418  PGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSM 477

Query: 347  -GVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH 405
             G PG  G  GR  PGP G PG  GL GE G  GP G  G +GP GPPG  G  G  G  
Sbjct: 478  KGPPGPVGLTGR--PGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGAD 535

Query: 406  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP 465
                L  +  P G  G+ GLPG+ G KG +G+ G      H G+ G  GE GE GA+GPP
Sbjct: 536  GARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFG------HVGQPGPPGEDGERGAEGPP 589

Query: 466  GAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR 525
            G  G  G  G  G  G +G+ G  G PG  G+ GAPG +G  GPPGE GP G +G  G++
Sbjct: 590  GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649

Query: 526  GIPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP 573
            G+PG             PG  G  GLPG DG  G PG  G  GE G  GPPG AG  G P
Sbjct: 650  GLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYP 709

Query: 574  G---VPGIPGAKGVAGEKGSTGAPGKPG------QMGNSGKPGQQGPPGEVGPRGPQGLP 624
            G   V G  G +G+ GEKG  G  G PG        G+ GKPG  GP GE GP GP+G  
Sbjct: 710  GPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQA 769

Query: 625  GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 684
            G  GE GP GS G  GKLG  G PG PG PGP G  G  G  G +GE G  G+ G  G E
Sbjct: 770  GQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLE 829

Query: 685  GE------AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 738
            GE       GERG+ G  G PGPKG  G  G PG+    G +GLPG++GP G PGP+G  
Sbjct: 830  GERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGFPGPKGPP 886

Query: 739  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD--SGATGLPGRPG 796
            G QG  G PG  G  G            +    +      A +  P   +G  G  G  G
Sbjct: 887  GHQGKDGRPGHPGQRGE-----------LGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935

Query: 797  PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP---------------KGDLGEKG 841
            PPGPPGPPGE G PG  G  G  G  GPPG LG  GP                G  G KG
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 842  ERGPPG----------RGPNGLPGAIGLPGDPGP----ASYGRNGRDGERGPPGVAGIPG 887
            ++GPPG          RGP G  G IGLPG  G        G+ G  GERGPPG  G  G
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDG 1055

Query: 888  VPGPPGPPGLPGFCEPA 904
            +PGP GP G PG   P+
Sbjct: 1056 IPGPLGPLGPPGAAGPS 1072



 Score =  506 bits (1302), Expect = e-143
 Identities = 308/691 (44%), Positives = 349/691 (50%), Gaps = 79/691 (11%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGID---GIDGDRGPKGPPGPPGPAGEPGK 312
            P    P+     +GPPG  GPPG PGP GV G     G+ G++G KG  G PG  G+ G 
Sbjct: 685  PGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGL 744

Query: 313  PGAPGKPGTPGADGLTGPDGSPGSI---------GSKGQKGEPGVPGSRGFPGR------ 357
             G  GKPG PG  G  GP+G  G           GS G+KG+ GVPG  G+PGR      
Sbjct: 745  KGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGS 804

Query: 358  -GIPGPPGP------PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 410
             G PGP GP       G  G PG  G  GP G  G RG PG  G PGP+G +G  DG P 
Sbjct: 805  IGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG-QDGAPG 863

Query: 411  CPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470
                  PG  G PGL G  G  G KG  G  G+ G  G  G +GELG  G  GPPG  G+
Sbjct: 864  I-----PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGV 918

Query: 471  RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 530
             G  G  G+ G  G RG  G PGP G  G PG +G+ G  GE GP G  G EG  G+ G 
Sbjct: 919  LGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978

Query: 531  PGPK---GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 587
            PGPK   GD G  G+ G  G PG  G  G PG+ GP G AG  GLPG  G  G  G AG+
Sbjct: 979  PGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGK 1038

Query: 588  KGS---------TGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGELGPVGS 635
            KGS         TG  G PG +G  G PG  GP GE G +G  G P   GS+G+ G  G 
Sbjct: 1039 KGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP 1098

Query: 636  PGLPGKLGSLGSPGLPGLP------GPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE 689
            PG PG  G  G PG PG        GPPGL G KGD GV G  G  G  G  G  G  GE
Sbjct: 1099 PGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE 1158

Query: 690  RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 749
            +GE+GD+G  GP G+   PG  G +GP GS G PG+ G  G PG  G +GE+G  G PG 
Sbjct: 1159 KGEVGDVGSMGPHGA---PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP 1215

Query: 750  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
             G PG       I                      + G +G  G  GPPG  GPPGE+G 
Sbjct: 1216 PGAPGIPGPKGDI---------------------GEKGDSGPSGAAGPPGKKGPPGEDGA 1254

Query: 810  PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASY 868
             G +G  GLPG  GPPG  G+ G  G  GEKG+ G  G GP G PGA G PG PG P   
Sbjct: 1255 KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG-GP-GPPGASGEPGAPGPPGKR 1312

Query: 869  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            G +G  G  G  G  G  G PGP GPPG  G
Sbjct: 1313 GPSGHMGREGREGEKGAKGEPGPDGPPGRTG 1343



 Score =  505 bits (1301), Expect = e-143
 Identities = 304/683 (44%), Positives = 355/683 (51%), Gaps = 86/683 (12%)

Query: 269  GPPGEQGPPGP---PGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTP 322
            G PGE+GPPG    PG PG  G  G  G  GP   KG  GPPG AG PG PG  G  GT 
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 323  GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRV 378
            G  GL G  G  G  G  G KG+ G+ G +G PG    RG  GP GP G AG  GE G  
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 379  GPVGDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCP--NACPPGRSGYPGLPGMRGHKG 433
            G  G+ G+ G    PG PG PGP+G+IGF    PL P       G++G PGL G RG  G
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGF--PGPLGPIGEKGKSGKTGQPGLEGERGPPG 836

Query: 434  AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPG 493
            ++GE G+PG  G  G +GD G+ G  G  G  G  GL+G  G  G KG  G +G DG PG
Sbjct: 837  SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPG 896

Query: 494  PQGLPGAPGDQGQRGPPGEAGPKGDRGAE------GARGIPGLPGPKGDTGLPGVDGRDG 547
              G  G  G QGQ GPPG AG  G +G        G RG PG PGP G+ GLPG++GR+ 
Sbjct: 897  HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE- 955

Query: 548  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 607
                 G KGE G PGP G  G  GL G PG  G  G  G  G  G  G PG +G +G PG
Sbjct: 956  -----GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010

Query: 608  QQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 667
            ++GP G  G  G  G  GS G +GP G  G  G+ G  G  G  G+PGP G  G  G  G
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070

Query: 668  VVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 727
              GE G KG+ GA G +G  G++G+ G  G PG +G AG+PG PG  G +G RG PG+ G
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFG 1130

Query: 728  PRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 787
             +G  G RG  G  G  GL G+ GPPG                     E+       D G
Sbjct: 1131 QKGDDGVRGFVGVIGPPGLQGLPGPPGEK------------------GEVG------DVG 1166

Query: 788  ATGLPGRPGPPGPPGPPGENGFP------------GQMGIRGLPGIKGPPGALGLRGPKG 835
            + G  G PGP GP GP G  G P            G+ G RG  G  GPPGA G+ GPKG
Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226

Query: 836  DLGEKGE------------RGPPGR-------GPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            D+GEKG+            +GPPG        GP GLPG +G PGDPG +  G +G  GE
Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS--GIDGSPGE 1284

Query: 877  RGPPGVAGIPGVPGPPGPPGLPG 899
            +G PG  G PG PG  G PG PG
Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPG 1307



 Score =  503 bits (1296), Expect = e-142
 Identities = 320/747 (42%), Positives = 365/747 (48%), Gaps = 130/747 (17%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPP---GVPGIDGIDGDRGP--------------- 297
            P    P       GPPG  G PG PGPP   G+PGI GIDG RGP               
Sbjct: 394  PGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGS 453

Query: 298  -KGPP--------------------GPPGPAGEPGKPGAPGKPGTPGAD----------- 325
             KGPP                    GPPGP G  G+PG  G PG PG             
Sbjct: 454  FKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP 513

Query: 326  -GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELGR 377
             GL GP G PG +   G+ G PG  G+RG PG       RG  G PG PG  G  G+ G 
Sbjct: 514  RGLQGPHGPPGRV---GKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGH 570

Query: 378  V---GPVGDPGRRGPPGPPGP------PGPRGTIGFHDGDPLCPNACP-----PGRSGYP 423
            V   GP G+ G RG  GPPGP      PGPRG +G        P   P     PG +G  
Sbjct: 571  VGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG--------PRGSPGPTGRPGVTGID 622

Query: 424  GLPGMRGHKGAKGEIGEPGRQGHKGEE---GDQGELGEVGAQGPPGAQGLRGITGI---- 476
            G PG +G+ G  GE G PG+QG+ G +   G QG +G  G +GPPG  G+ G+ G     
Sbjct: 623  GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPL 682

Query: 477  -----VGDKGEKGARGLDGEPGPQGLP---GAPGDQGQRGPPGEAGPKGDRGAEGARGIP 528
                  G  GEKGA+G  G  GP G P   G  G  G RG  GE G KG+ G  G +G  
Sbjct: 683  GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742

Query: 529  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEK 588
            GL G +G  G PG  G DG  G  G  G+ G+ GPPG AG +G  GVPG+PG  G  G K
Sbjct: 743  GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK 802

Query: 589  GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 648
            GS G PG  G +G  GK G+ G PG  G RGP   PGSRGE G  G+ G PG  G +G  
Sbjct: 803  GSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP---PGSRGERGQPGATGQPGPKGDVGQD 859

Query: 649  GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP 708
            G PG+PG  GLPG++G  G  G  GP G QG  G  G  G+RGELG  G  GP      P
Sbjct: 860  GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGP------P 913

Query: 709  GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMR 768
            G  G+ GP+G  G  G  G RGPPGP G  GEQG  GL G +G  G       + +    
Sbjct: 914  GPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK---- 969

Query: 769  VIQEHFAEMAASLKRPDSGATGLPGRPGP------PGPPGPPGENGFPGQMGIRGLPGIK 822
                   E  A L R   G  G PG PGP       GPPGP G NG PG+ G  G  G  
Sbjct: 970  -------EGPAGL-RGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021

Query: 823  GPPGALGLRGPKGDLGEK---GERGPPG-RGPNGLPGAIGLPGDPGPAS-YGRNGRDGER 877
            G PG  G  GP G  G+K   GERGPPG  G +G+PG +G  G PG A   G  G  G+ 
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDV 1081

Query: 878  GPPGVAGIPGVPGPPGPPGLPGFCEPA 904
            G PG  G  G  G  GPPG PG   PA
Sbjct: 1082 GAPGHKGSKGDKGDAGPPGQPGIRGPA 1108



 Score =  502 bits (1292), Expect = e-142
 Identities = 327/820 (39%), Positives = 380/820 (46%), Gaps = 181/820 (22%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGP----------------KGPP----------- 301
            GPPG  G PGPPGP G+PGI GIDG RGP                KGPP           
Sbjct: 410  GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469

Query: 302  ---------GPPGPAGEPGKPGAPGKPGTPGADG------------LTGPDGSPGSIGSK 340
                     GPPGP G  G+PG  G PG PG  G            L GP G PG +G  
Sbjct: 470  LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 341  GQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELGRVG---PVGDPGRRGPP 390
            G+   PG  G+RG PG       RG  G PG PG  G  G+ G VG   P G+ G RG  
Sbjct: 530  GR---PGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAE 586

Query: 391  GPPGP------PGPRGTIGFHDGDPLCPNACP-----PGRSGYPGLPGMRGHKGAKGEIG 439
            GPPGP      PGPRG +G        P   P     PG +G  G PG +G+ G  GE G
Sbjct: 587  GPPGPTGQAGEPGPRGLLG--------PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPG 638

Query: 440  EPGRQGHKGEEG---DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 496
             PG+QG+ G +G    QG +G  G +GPPG  G+ G+ G  G  G  G  G  GE G QG
Sbjct: 639  PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQG 698

Query: 497  LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG---LPGPKGDTGL---------PGVDG 544
             PG+ G  G  GP G  G  G+RG +G +G  G    PG KGD GL         PG  G
Sbjct: 699  PPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758

Query: 545  RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604
             DG  G  G  G+ G+ GPPG AG +G  GVPG+PG  G  G KGS G PG  G +G  G
Sbjct: 759  EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818

Query: 605  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
            K G+ G PG  G RGP   PGSRGE G  G+ G PG  G +G  G PG+PG  GLPG++G
Sbjct: 819  KSGKTGQPGLEGERGP---PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQG 875

Query: 665  DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG---------------NPG 709
              G  G  GP G QG  G  G  G+RGELG  G  GP G AG                 G
Sbjct: 876  PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935

Query: 710  EPGLRGPEGSRGLPGVEG---------PRGP------------PGPRGVQGEQGATGLPG 748
             PG  GP G +GLPG+EG         P GP            PGP+G  G+ G TGL G
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 749  VQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG 808
             +GPPG    +    +               S      G  G  G  G  GPPGP G++G
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDG 1055

Query: 809  FPGQMGIRGLPGIKGPPGA------LGLRGPKGDLGEKGERGPPG----RGPNGLPGAIG 858
             PG +G  G PG  GP G       +G  G KG  G+KG+ GPPG    RGP G PG  G
Sbjct: 1056 IPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPG 1115

Query: 859  LPGDPG----PASYGRNGRDGERG------PPGVAGIPG------------------VPG 890
              G  G    P  +G+ G DG RG      PPG+ G+PG                   PG
Sbjct: 1116 ADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPG 1175

Query: 891  PPGP---------PGLPGFCEPASCTMQAGQRAFNKGPDP 921
            P GP         PGLPG         + G+R     P P
Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP 1215



 Score =  477 bits (1228), Expect = e-134
 Identities = 279/605 (46%), Positives = 323/605 (53%), Gaps = 56/605 (9%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P   T E GP GE+GPPGPPGPPG  G+ G++G  G KG  GPPGP G+ G  G  G PG
Sbjct: 921  PQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPG 980

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
              G     GP G PG  G KG KG PG  G+ G PG    GP GP G  GLPG+ G  GP
Sbjct: 981  PKG-----GP-GDPGPTGLKGDKGPPGPVGANGSPGER--GPLGPAGGIGLPGQSGSEGP 1032

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
            VG  G++G  G  GPPGP G     DG P      P G  G PG  G  G +G KG++G 
Sbjct: 1033 VGPAGKKGSRGERGPPGPTGK----DGIP-----GPLGPLGPPGAAGPSGEEGDKGDVGA 1083

Query: 441  PGRQGHKGEEGDQGELGEVGAQGPPG---------AQGLRGITGIVGDKGEKGARGLDGE 491
            PG +G KG++GD G  G+ G +GP G         AQG RG  G+ G KG+ G RG  G 
Sbjct: 1084 PGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGV 1143

Query: 492  PGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGM 551
             GP GL G PG      PPGE G  GD G+ G  G PG  GP+G TG  G  G  G  G 
Sbjct: 1144 IGPPGLQGLPG------PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQ 1197

Query: 552  PGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGP 611
            PG  GE G+ G   DAG  G PG PGIPG KG  GEKG +G  G       +G PG++GP
Sbjct: 1198 PGAVGEKGERG---DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA------AGPPGKKGP 1248

Query: 612  PGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE 671
            PGE G +G  G  G  G+LGP G PG+ G  GS G  G PG  G PG PG  G+ G  G 
Sbjct: 1249 PGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGP 1308

Query: 672  PG---PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 728
            PG   P G  G  G EGE G +GE G  G PG  G  G  G PG  GPEG RG+PG  G 
Sbjct: 1309 PGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGE 1368

Query: 729  RG---PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
             G    PG  G  G  G +GLPG++G  G      HI  + +            + ++ D
Sbjct: 1369 PGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGL------IGPPGEAGEKGD 1422

Query: 786  SGATGLPGRPGP---PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
             G  G+ G PGP   PGPPGP G  G PG  G+ G  G KG  G+ G  GP+GD G  G 
Sbjct: 1423 QGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGP 1482

Query: 843  RGPPG 847
             GPPG
Sbjct: 1483 PGPPG 1487



 Score =  471 bits (1213), Expect = e-132
 Identities = 289/670 (43%), Positives = 324/670 (48%), Gaps = 76/670 (11%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 314
            LP    P      +GPPG QG  G PG PG  G  G  G  GP GP G  GP G+ G+ G
Sbjct: 870  LPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG 929

Query: 315  APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAG 370
              G+ G PG  G  G  G PG  G +G KGE G PG  G  G    RG PGP G PG  G
Sbjct: 930  PLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPG 989

Query: 371  LPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRG 430
              G  G  GP G  G  G PG  GP GP G IG             PG+SG  G  G  G
Sbjct: 990  PTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGL------------PGQSGSEGPVGPAG 1037

Query: 431  HKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 490
             KG++GE G PG  G  G  G  G LG  GA GP G +G +G  G  G KG KG +G  G
Sbjct: 1038 KKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAG 1097

Query: 491  EPGPQGL---------PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG 541
             PG  G+         PGA G QG+RGPPG  G KGD G  G  G+ G PG +G  G PG
Sbjct: 1098 PPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPG 1157

Query: 542  VDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS---------TG 592
              G  G  G  G  G PG  GP G  G +G PG+PG  G  G  GEKG           G
Sbjct: 1158 EKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG 1217

Query: 593  APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPG 652
            APG PG  G+ G+ G  GP G  GP G +G PG  G  G VG  GLPG LG  G PG+ G
Sbjct: 1218 APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSG 1277

Query: 653  LPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP---G 709
            + G PG  G  GD G  G PG  GE GA G  G+ G  G +G  G  G KG+ G P   G
Sbjct: 1278 IDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDG 1337

Query: 710  EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
             PG  GP G+RG PG  GP G  G  G  GE G  G PG  GPPG               
Sbjct: 1338 PPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPG--------------- 1382

Query: 770  IQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 829
                         + D+G  G  G  G  G  GPPGE    G+ G +GLPG++GPPG  G
Sbjct: 1383 ---PLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGE---AGEKGDQGLPGVQGPPGPKG 1436

Query: 830  LRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGV 888
              GP G +G  G  GPPG  GP G  G+ G PG  GP         G+ GP         
Sbjct: 1437 DPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPR--------GDTGP--------- 1479

Query: 889  PGPPGPPGLP 898
             GPPGPPG P
Sbjct: 1480 AGPPGPPGAP 1489



 Score =  433 bits (1114), Expect = e-121
 Identities = 329/939 (35%), Positives = 398/939 (42%), Gaps = 166/939 (17%)

Query: 86  AYKLGNNVDFRIPTRNLYPSG-LPEEYSFLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGI 144
           A+++G      IPT  L+P G  PE +S L T R  G    ++  +  I D  G  Q+G+
Sbjct: 64  AFRIGQASTLGIPTWELFPEGHFPENFSLLITLR--GQPANQSV-LLSIYDERGARQLGL 120

Query: 145 KINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIESL 204
            +      +   ++ L   +         +L D +WH++ + ++    TL  DC      
Sbjct: 121 ALGPALGLLGDPFRPLPQQV---------NLTDGRWHRVAVSIDGEMVTLVADCEA--QP 169

Query: 205 PIKPRGP--IDIDGFAVLGKLADNPQVSVPFELQWMLIHCDPLRPRRETCHELPA--RIT 260
           P+   GP  I I G  VLG   D  + +   ++Q +LI  DP    +     LP    + 
Sbjct: 170 PVLGHGPRFISIAGLTVLGT-QDLGEKTFEGDIQELLISPDPQAAFQACERYLPDCDNLA 228

Query: 261 PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP----------PGPPGPAGE- 309
           P+ T         QG P  P P       G    RG KG             PP  + E 
Sbjct: 229 PAATV------APQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAEN 282

Query: 310 -------PGKPGAPGKPGTP---------------------------------------- 322
                    +  AP  P TP                                        
Sbjct: 283 QTSTDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAARE 342

Query: 323 ---GADGLTGPDGS-------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366
              G D   GPD               PG+ G KG KGEP V       G+   GPPG P
Sbjct: 343 DEEGDDSTMGPDFRAAEYPSRTQFQIFPGA-GEKGAKGEPAVIEK----GQQFEGPPGAP 397

Query: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSG--YPG 424
           G  G+ G  G  GP G PG  GPPGP G PG  G  G   G P      P   +G  + G
Sbjct: 398 GPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIR-GPPGTVIMMPFQFAGGSFKG 456

Query: 425 LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 484
            P       A+  + +  +   KG  G  G  G  G  G PG  GL+G  G  G +G +G
Sbjct: 457 PPVSFQQAQAQAVLQQT-QLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRG 515

Query: 485 ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD------TG 538
            +G  G PG  G  G PG  G RG PG+ GPKGDRG +G  G+PG  G +GD       G
Sbjct: 516 LQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPG 575

Query: 539 LPGVDGRDGIPGMPGTKGEPGKPGPPG------DAGLQGLPGVPGIPGAKGVAGEKGSTG 592
            PG DG  G  G PG  G+ G+PGP G        G  G PGV GI GA G  G  G  G
Sbjct: 576 PPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPG 635

Query: 593 APGKPGQMGNSGKPGQQGP------PGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG 646
            PG PGQ GN G  G  GP      PGE GP G  G+PG  G  GP+G PG  G  G  G
Sbjct: 636 EPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKG 695

Query: 647 SPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706
           + G PG  GPPG PG    RGV G  G +G QG  GE+GE G  G  GD+GL G +G  G
Sbjct: 696 AQGPPGSAGPPGYPG---PRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPG 752

Query: 707 NPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVC 766
            PG  G  GPEG +G  G  G  GPPG  G +G+ G  GLPG  G PG            
Sbjct: 753 APGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPG------------ 800

Query: 767 MRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP-- 824
                               G+ G PG  GP G  G  G+ G PG  G RG PG +G   
Sbjct: 801 ------------------PKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERG 842

Query: 825 -PGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGV 882
            PGA G  GPKGD+G+ G  G PG    GLPG  G PG PGP    G  G+DG  G PG 
Sbjct: 843 QPGATGQPGPKGDVGQDGAPGIPGE--KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQ 900

Query: 883 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
            G  G  G  GPPG  G   P   T + G       P P
Sbjct: 901 RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGP 939


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  518 bits (1335), Expect = e-147
 Identities = 317/727 (43%), Positives = 360/727 (49%), Gaps = 107/727 (14%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            E G  GE+GPPGP G  G+PG+ G  G +GP+GPPGP G  GE G+PG PG P   G   
Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP-A 1548

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGT------------AGLPGE 374
            + GP G  G +G  G +G  GV G RG PG  +PG PGP G             AG PG+
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 375  LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSGYPGLPGMR 429
             G  G  GDPGR GPPGP GP G  G +G        GDP  P     G  G  G PG+R
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKA--GERGLRGAPGVR 1666

Query: 430  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI-VGDKGEKGARGL 488
            G  G KG+ G+PG  G  G  G  G  G+ G  GPPG  G    TG    +KGE G RG 
Sbjct: 1667 GPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ 1726

Query: 489  DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 548
            +G  GP+G PG PG  G+RG  G  GP G +G  G RG  G    KGD G PG+DGR G+
Sbjct: 1727 EGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAG---EKGDRGPPGLDGRSGL 1783

Query: 549  PGMPGT------KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
             G PG        G  GK G PG  GL GL G  G+PG  G  G  G  G  GKPG  G 
Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK 1843

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP-----P 657
            +G+PG  G  G  G +G  G  G  G  GP G  G PG LG  G PGLPG  GP     P
Sbjct: 1844 NGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP 1903

Query: 658  GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE---------------------------- 689
            G+PG  G +G  GE G KGEQG  GE G  GE                            
Sbjct: 1904 GVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETW 1963

Query: 690  --------------RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP------- 728
                          RG  GD G  GP G  G  G PG RG +G RG PG +GP       
Sbjct: 1964 DESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGE 2023

Query: 729  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 788
            RGPPGP G+ GE G  G+PG+   PGRA       +   R       E     +R + G 
Sbjct: 2024 RGPPGPSGLAGEPGKPGIPGL---PGRAGGVGEAGRPGER------GERGEKGERGEQGR 2074

Query: 789  TGLPGRPGPPGPPGPPGEN--------GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE- 839
             G PG PG PGPPGPPG          G  G+ G  GL G KG PG+ G +GPKGD G  
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134

Query: 840  --KGERGPPGRGPNGLPGAIGLPGDPGPAS-YGRNGRDGERGPPGVAGIPGVPGPPGPPG 896
              KG+RG P  GP G  G  GLPG+ G A   G+ G  G RGPPG  G  G PGPPG PG
Sbjct: 2135 GIKGDRGEP--GPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPG 2192

Query: 897  LPGFCEP 903
            L G   P
Sbjct: 2193 LAGPAGP 2199



 Score =  505 bits (1301), Expect = e-143
 Identities = 319/738 (43%), Positives = 376/738 (50%), Gaps = 99/738 (13%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ERG  GE+G  G  GPPG+PG  G      P GPPGP     EPG    PG  G  G  G
Sbjct: 2062 ERGEKGERGEQGRDGPPGLPGTPG------PPGPPGPKVSVDEPG----PGLSGEQGPPG 2111

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 386
            L G  G PGS G +G KG+ GVPG +G   RG PGP G  G  GLPGE G  GP G PG 
Sbjct: 2112 LKGAKGEPGSNGDQGPKGDRGVPGIKG--DRGEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169

Query: 387  RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP--------GMRGHKGAKGEI 438
            +GP GPPGP G  G  G      L   A P G SG  G P        G+ G  GA G  
Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229

Query: 439  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGL---------D 489
            G PG  G  G +G  G  G+VG  G PGA G  G +G  GD+G  G  G           
Sbjct: 2230 GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPK 2289

Query: 490  GEPGPQGLP-----GAPGDQGQRGPP--------GEAGPKGDRGAEGARGIPGLPGPKGD 536
            GEPGP G P     G PG +G++G P        GE G KGDRG  G RG  G  G  G+
Sbjct: 2290 GEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE 2349

Query: 537  TGLPGVDGRDGIPGMPGTKGE-----PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST 591
             G PG DG+ G PG  G KG+     PG PGPPG  G++G  G+PG+PGA GV G  G T
Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQT 2409

Query: 592  GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS------- 644
            G  G+ GQ G SG+ G  GPPG  G  GP G PG  G +GP G+ GL G  G        
Sbjct: 2410 GPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG 2469

Query: 645  -LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD----IGLP 699
              G  G PG+ G  G PG +G RG+ G PG +GE+G  G+ G AG +G+ GD    +G P
Sbjct: 2470 PRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPP 2529

Query: 700  GPKGSAGNPGEPGLR------GPEGSRGLPGVEGPRGPPGPR------------GVQGEQ 741
            GP+G+ G+ GE G R      GP G  G PG +G +G PG +            G QG+ 
Sbjct: 2530 GPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQP 2589

Query: 742  GATGLPGVQGPPGR------APTDQHIKQVCMRVIQ-EHFAEMAASL--KRPDSGATGLP 792
            GA G+PG  G PG+            +  +  R ++ E   + A  L  ++ D G  G P
Sbjct: 2590 GAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPP 2649

Query: 793  GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL---RGPKGDLGEKGERGPPG-- 847
            GRPG  G  G  GE G PGQ G  G  G+ GP G  G     GPKGD GEKGERG PG  
Sbjct: 2650 GRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIG 2709

Query: 848  --RGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGPPG--VAGIPGVPGPPGPPGLPG 899
               GP+G  G+ G PG PG        G  G+ GERGPPG  V G PGVPG PG  G  G
Sbjct: 2710 GFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQG 2769

Query: 900  FCEPASCTMQAGQRAFNK 917
               PA    + G+ A  +
Sbjct: 2770 RPGPAGPRGEKGEAALTE 2787



 Score =  502 bits (1293), Expect = e-142
 Identities = 310/697 (44%), Positives = 362/697 (51%), Gaps = 122/697 (17%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G PGE G  G  GPPG PG+ G  G  GP+GPPG     GE G PGA G+PG+PG   
Sbjct: 1255 QKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR-- 1312

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE-LGRVGPVGDPG 385
                 G+PG+ G+ G KG PG+PG RG PG    GP GP G  G PG+ +G  GP G PG
Sbjct: 1313 ----AGNPGTPGAPGLKGSPGLPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEGP-GLPG 1365

Query: 386  RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPG--MRGHKGAKGEIGEPGR 443
            R+G PGP GPPGPRG +G             PG  G PGLPG  M+G KG +GE G PG 
Sbjct: 1366 RKGDPGPSGPPGPRGPLG------------DPGPRGPPGLPGTAMKGDKGDRGERGPPG- 1412

Query: 444  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503
                GE G     GE G  G PG+ G +G  G  G KGEKG    DG PG  G PG+PG+
Sbjct: 1413 ---PGEGGIAP--GEPGLPGLPGSPGPQGPVGPPGKKGEKG-DSEDGAPGLPGQPGSPGE 1466

Query: 504  QGQRGPPGEAGPKGDR------GAEGARGIPGLPGPKGDTGLPGVDGR------DGIPGM 551
            QG RGPPG  GPKGDR      G  G +G  G PGP G  GLPGV GR      +G PG 
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP 1526

Query: 552  PGTKGEPGKPGPPGD--------------------AGLQGLPGV-----------PGIPG 580
             G +GE G+PG PGD                    AG +G  GV           PG PG
Sbjct: 1527 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPG 1586

Query: 581  AKGVAGEKGSTGAPGKPGQMGNSGKPGQQ------GPPGEVGPRGPQGLPGSRGELGPVG 634
             KG  G++G  G  G+ G  G+SG PG++      GPPG VGPRG  G  G +G+ GP G
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646

Query: 635  SPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 694
             PGLPGK G  G  G PG+ GP G  G +GD G  G  G  G  G  G+ GE G  G  G
Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG 1706

Query: 695  DIGLPGP----KGSAGNPGEPGLRGPEGSRGLP------GVEGPRGPPGPRGVQGEQGAT 744
             +   GP    KG  G+ G+ G RGP+G  GLP      G+EG RGPPGP+G  G +G  
Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 745  GLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPP 804
            G  G +GPPG                                G +GL G+PG  GP GP 
Sbjct: 1767 GEKGDRGPPGL------------------------------DGRSGLDGKPGAAGPSGPN 1796

Query: 805  GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDP 863
            G  G  G  G  GLPG++G  G  G  GP G  G+ GE G PG  G NG PG  G  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 864  G-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            G     G +GR+G  GP G  G PG+ GP GPPGLPG
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPG 1893



 Score =  485 bits (1249), Expect = e-137
 Identities = 307/722 (42%), Positives = 355/722 (49%), Gaps = 120/722 (16%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT--PGA 324
            E G PGE G  G  G  G  G +G DG +G +G PG  GP G PG PG  G PG   PG 
Sbjct: 1846 EPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGV 1905

Query: 325  DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG-------------------------- 358
             G TGP G  G  GSKG++G PG  G RG PG                            
Sbjct: 1906 PGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDE 1965

Query: 359  -----IPGPP---GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 410
                 +P P    GP G +G  G  G+ GP+G PG RG  G  G PGP+G  G   G+  
Sbjct: 1966 SSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERG 2025

Query: 411  CPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 470
             P   P G +G PG PG+ G  G  G +GE GR G +GE G++GE GE G  GPPG  G 
Sbjct: 2026 PPG--PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGT 2083

Query: 471  RGITGIVGDKG--EKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP 528
             G  G  G K   ++   GL GE GP GL GA G+ G  G   + GPKGDRG  G +G  
Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG---DQGPKGDRGVPGIKGDR 2140

Query: 529  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEK 588
            G PGP+G  G PG+ G  G+ G  G  G  G  GPPG  G  G PG PG PG  G AG +
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 589  GSTGAPGKPGQMGNSGK-----------PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            G +G  G+PG+ G  G+           PG  GP G VGP+G  GLPG  GE G  G+PG
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 638  LPGKLGSLGSPGLPGLPGPPGLPGMKGDRG-----------VVGEPGPKGEQGA-SGEEG 685
              G  G  G  G PG+PG PGLPG  G +G           VVG PG KGE+GA  G  G
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAG 2320

Query: 686  E-AGERGELGDIGLPGP---KGSAGNPGEPGLRGPEGSRGLP-----------GVEGPRG 730
            +  GE G  GD GLPGP   KG AG  GEPG  G +G +G P           GV G  G
Sbjct: 2321 DLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPG 2380

Query: 731  PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 790
            PPGP GV+G+ G  GLPG  G  G                           +    G  G
Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPG------------------------QTGPRGEMG 2416

Query: 791  LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD-----LGEKGERGP 845
             PG  G  G  GPPG  G PG +G  G PG  GPPGA GL+G KGD      G +GERG 
Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGE 2476

Query: 846  PG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPG-------VPGPPGPPGL 897
            PG RG +G PG  G  G  GP   G  G  GE+G  G AG+ G       + GPPGP G 
Sbjct: 2477 PGIRGEDGRPGQEGPRGLTGPP--GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGA 2534

Query: 898  PG 899
             G
Sbjct: 2535 KG 2536



 Score =  481 bits (1239), Expect = e-135
 Identities = 331/823 (40%), Positives = 379/823 (46%), Gaps = 178/823 (21%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            + GPPGE+G PG PGPPG  G  G DG+ G KG  GPPG  G PGK G  G  G PG  G
Sbjct: 1608 DSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG 1667

Query: 327  LTGP------------DGSPGSIGSKGQKGEPGVPG-------------SRGFPG----- 356
              G             +GSPGS G KG +GEPG PG              +G PG     
Sbjct: 1668 PVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727

Query: 357  -----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH--DGDP 409
                 +G PG PG PG  G+ G  G  GP GDPG RGP G  G  GP G  G    DG P
Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787

Query: 410  LCPNACPP----GRSGYPG---LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ 462
                   P    G++G PG   LPG+RG +G  G  G PG  G  GE+G  G  G+ G  
Sbjct: 1788 GAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEP 1847

Query: 463  GPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAE 522
            G PG  G +G      +KG+ GA G +G  GP+G  GAPG  G +GPPG  GP G  G +
Sbjct: 1848 GDPGEDGRKG------EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPG-Q 1900

Query: 523  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG----------------------- 559
            G  G+PG  GPKGD G  G  G  G+PG  G +GEPG                       
Sbjct: 1901 GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIV 1960

Query: 560  ----------------KPGPPGDAGLQGLPGVPG---IPGAKGVAGEKGSTGAPGKPG-Q 599
                            + GP GD+G QG PG  G    PG +G+ G++G  G  G PG  
Sbjct: 1961 ETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLA 2020

Query: 600  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS---------PGL 650
            +G  G PG  G  GE G  G  GLPG  G +G  G PG  G+ G  G          PGL
Sbjct: 2021 LGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGL 2080

Query: 651  PGLPGPPGLPGMK-----------GDRGVVGEPGPKGEQGASGEEGEAGERGE---LGDI 696
            PG PGPPG PG K           G++G  G  G KGE G++G++G  G+RG     GD 
Sbjct: 2081 PGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDR 2140

Query: 697  GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP------------------RGVQ 738
            G PGP+G  GNPG PG RG  G  G PG++GPRGPPGP                   G Q
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 739  GEQGATGLPGVQGPPGRAPTDQHIK-----------------------QVCMRVIQEHFA 775
            G  G  G PG  GPPGR  T                            QV          
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPG 2260

Query: 776  EMAASLKRPDSGATGLPGRPGPPGPPGP---PGENGFPGQMGIRGLPGIKGPPGALGLRG 832
               AS K  D G+ G+PG PG PGP GP   PG  G PGQ  + GLPG KG  GA G  G
Sbjct: 2261 RDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ-AVVGLPGAKGEKGAPG--G 2317

Query: 833  PKGDL----GEKGERGPPG-RGPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVA--- 883
              GDL    G KG+RG PG RG  G  G  G PGDPG     G  G  G +G PGV    
Sbjct: 2318 LAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPG 2377

Query: 884  -----GIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921
                 G PGV G  G PGLPG         Q G R     P P
Sbjct: 2378 SPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGP 2420



 Score =  459 bits (1180), Expect = e-129
 Identities = 285/685 (41%), Positives = 337/685 (49%), Gaps = 106/685 (15%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK-----PGAPGKPGTP 322
            RGPPG  G  G PGPPG PG+ G  G +GP G  G PG  G PG+      GA G PG P
Sbjct: 2173 RGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP 2232

Query: 323  GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPV 381
            G  GL GP GSPG  G  G+ G+PG PG  G  G+ G  G PG PG+ GLPG    VGP 
Sbjct: 2233 GPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGP---VGPK 2289

Query: 382  GDPGRRGPPGP-----PGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 436
            G+PG  G PG      PG  G +G  G   GD +      PG  G  GLPG RG KG  G
Sbjct: 2290 GEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE----PGAKGDRGLPGPRGEKGEAG 2345

Query: 437  EIGEPGRQGHKGEEGDQGE--------LGEVGAQGPPGAQGLRG---------ITGIVGD 479
              GEPG  G  G++G  G         +G  G+ GPPG  G++G           G+VG 
Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405

Query: 480  KGEKGARGLDGEPGPQG---------LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG- 529
             G+ G RG  G+PGP G           G PG  G  GPPG  GP G  G +G +G PG 
Sbjct: 2406 PGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV 2465

Query: 530  -LPGPKGDTGLPGVDGRDGIPGM---------PGTKGEPGKPGPPGDAGLQG-------L 572
             LPGP+G+ G PG+ G DG PG          PG++GE G+ G  G AGL+G       +
Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525

Query: 573  PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 632
             G PG  GAKG  GE+G  G  G  G  G++G PG +G  GE G +G  GLPG RG LGP
Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP 2585

Query: 633  VGSPG---LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE 689
             G PG   +PG  GS G  G+PG+ G  G  G  G RG+ GE G KG  G  GE+G+ GE
Sbjct: 2586 QGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGE 2645

Query: 690  RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG---PPGPRGVQGEQGATGL 746
             G  G  GL G KG  G PG PG  G  G  GL G +G RG    PGP+G QGE+G  G 
Sbjct: 2646 AGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGT 2705

Query: 747  PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 806
            PG+ G PG                               SG  G  G PGPPG  GP G 
Sbjct: 2706 PGIGGFPG------------------------------PSGNDGSAGPPGPPGSVGPRGP 2735

Query: 807  NGFPGQMGIRG--------LPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIG 858
             G  GQ G RG         PG+ G PG  G +G  G  G +GE+G      + + G + 
Sbjct: 2736 EGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVR 2795

Query: 859  LPGDPGPASYGRNGRDGERGPPGVA 883
                   A  G+    G R  P  A
Sbjct: 2796 QEMSQHCACQGQFIASGSRPLPSYA 2820



 Score =  427 bits (1099), Expect = e-119
 Identities = 273/623 (43%), Positives = 313/623 (50%), Gaps = 108/623 (17%)

Query: 340  KGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPR 399
            KGQKGEPG  G RG          GPPG  GLPG  G  GP          GPPG    +
Sbjct: 1253 KGQKGEPGEMGLRG--------QVGPPGDPGLPGRTGAPGP---------QGPPGSATAK 1295

Query: 400  GTIGF--HDGDPLCP-NACPPGRSGYPGL------------PGMRGHKGAKGEIGE---- 440
            G  GF   DG P  P  A  PG  G PGL            PG RG +G KGE G     
Sbjct: 1296 GERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV 1355

Query: 441  --------PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG----- 487
                    PGR+G  G  G  G  G +G  GP G  GL G T + GDKG++G RG     
Sbjct: 1356 IGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG-TAMKGDKGDRGERGPPGPG 1414

Query: 488  ----LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP------GPKGDT 537
                  GEPG  GLPG+PG QG  GPPG+ G KGD   +GA G+PG P      GP+G  
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGD-SEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 538  GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKP 597
            G  G  G  G PG  G  GE G+ GPPG AG +GLPGV G PGAKG  G  G TG  G+ 
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK 1533

Query: 598  GQMGNSGKP--------GQQGPPGEVGPRGPQGLPGSRGELGP-----VGSPGLPGKLGS 644
            G+ G  G P        G +G  G+VGP GP+G  G +GE GP      G PG  G  G 
Sbjct: 1534 GEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD 1593

Query: 645  LGSPGLPGLPGPP---GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
             G  GL G  GPP   G PG KGD G  G PGP G +G  GE GE G+ G  GD GLPG 
Sbjct: 1594 RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGK 1653

Query: 702  KGSAGNPGEPGLRGP---EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPT 758
             G  G  G PG+RGP   +G +G PG +G  G PG  G +G++G    PG  GPPGR   
Sbjct: 1654 AGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE---PGPPGPPGRLVD 1710

Query: 759  DQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGL 818
                                     P +   G PG  G  GP GP G+ G PG  G RG+
Sbjct: 1711 -----------------------TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGI 1747

Query: 819  PGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGP-ASYGRNGRDGE 876
             G +GPPG  G  G +G  GEKG+RGPPG  G +GL G  G  G  GP  + G+ G  G 
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807

Query: 877  RGPPGVAGIPGVPGPPGPPGLPG 899
             G PG+ G  G+PGP GPPGLPG
Sbjct: 1808 DGLPGLRGEQGLPGPSGPPGLPG 1830



 Score =  415 bits (1066), Expect = e-115
 Identities = 268/629 (42%), Positives = 312/629 (49%), Gaps = 117/629 (18%)

Query: 261  PSQTTDERGPPGEQGPPG-----PPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P   +  +G PGE GPPG     P G  G+PG  G  G  GP+G PG PG  GE GKPGA
Sbjct: 2199 PQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGA 2258

Query: 316  PGK---------------PGTPGADGLTGPDGSPGSIGSKGQK--GEPGVPGSRGFPG-- 356
            PG+               PG+PG  G  GP G PG  G+ GQ   G PG  G +G PG  
Sbjct: 2259 PGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGL 2318

Query: 357  -------------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGP-------------- 389
                         RG+PGP G  G AG  GE G  G  G  G  GP              
Sbjct: 2319 AGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGS 2378

Query: 390  PGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGE 449
            PGPPGPPG +G +G     P  P A  PG  G+PG  G RG  G  G  GE G  G  G 
Sbjct: 2379 PGPPGPPGVKGDLGL----PGLPGA--PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432

Query: 450  EGDQGELGEVG---AQGPPGAQGLRG--------ITGIVGDKGEKGARGLDGEPG---PQ 495
            EG  G LG  G   + GPPGA GL+G        + G  G++GE G RG DG PG   P+
Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR 2492

Query: 496  GLPGAPGDQGQRGPPGE---AGPKGDRGAEGA-RGIPGLPGPKGDTGLPGVDGRDGIPGM 551
            GL G PG +G+RG  G+   AG KGD+G      G PG  G KGD G  G  G DG  G 
Sbjct: 2493 GLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGP 2552

Query: 552  PGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGP 611
             G  G+PG  G  G+ G +G  G+PG+ G  G  G+ G+ G PG PG  G  G PG +G 
Sbjct: 2553 RGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGE 2612

Query: 612  PGEVGPRGPQGLPGSRG---------------ELGPVGSPGLPGKLGSLGSPGLPG---L 653
             G+VG  GP+GL G RG               E GP G PGL G  G +G PG+PG    
Sbjct: 2613 KGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA 2672

Query: 654  PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK---GSAGNPGE 710
            PG  GL G KGDRG  G+PGPKG+Q      GE GERG  G  G PGP    GSAG PG 
Sbjct: 2673 PGKEGLIGPKGDRGFDGQPGPKGDQ------GEKGERGTPGIGGFPGPSGNDGSAGPPGP 2726

Query: 711  PGLRGPEGSRGLPGVEGPRGPPGPR--------GVQGEQGATGLPGVQGPPGR----APT 758
            PG  GP G  GL G +G RGPPG R        G  GE+G  G PG  GP G     A T
Sbjct: 2727 PGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALT 2786

Query: 759  DQHIKQVCMRVIQEHFA---EMAASLKRP 784
            +  I+    + + +H A   +  AS  RP
Sbjct: 2787 EDDIRGFVRQEMSQHCACQGQFIASGSRP 2815



 Score =  372 bits (955), Expect = e-103
 Identities = 232/576 (40%), Positives = 277/576 (48%), Gaps = 103/576 (17%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGI---DGDRGPKGPPGPPG------ 305
            LP    PS     +G PG  G  G  G PG PG DG    DGDRG  G PG PG      
Sbjct: 2228 LPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG 2287

Query: 306  PAGEPGKPGAPGK-------------------------PGTPGADGLTGPDGS------- 333
            P GEPG  GAPG+                         PG  G  GL GP G        
Sbjct: 2288 PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRA 2347

Query: 334  --PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG--------------- 376
              PG  G  GQKG PG  G +G PG G+PG PGPPG  G+ G+LG               
Sbjct: 2348 GEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPG 2407

Query: 377  RVGPVGD---------------PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSG 421
            + GP G+               PGR G PGP GPPGP G++G      L  +   PG  G
Sbjct: 2408 QTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VG 2466

Query: 422  YPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITG------ 475
             PG  G RG  G +GE G PG++G +G  G  G  GE G +G  G+ GL+G  G      
Sbjct: 2467 LPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526

Query: 476  -------IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP 528
                     GD GE+G RGLDG+ GP+G  G PGD+G +G PG+ G  G  G  G  G  
Sbjct: 2527 GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQ 2586

Query: 529  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEK 588
            G PG  G  G PG  G+DG+PG+ G KG+ G  GP    GL+G  GV G  G  G  G+K
Sbjct: 2587 GQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP---RGLKGERGVKGACGLDGEKGDK 2643

Query: 589  GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 648
            G  G PG+PG  G+ G+ G+ G PG+ G  G +GL G +G+ G  G PG  G  G  G  
Sbjct: 2644 GEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGER 2703

Query: 649  GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP 708
            G PG+    G PG  G+ G  G PGP G  G  G EG  G++GE G    P  +   G P
Sbjct: 2704 GTPGI---GGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERG----PPGERVVGAP 2756

Query: 709  GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT 744
            G PG  G  G +G P      GP GPRG +GE   T
Sbjct: 2757 GVPGAPGERGEQGRP------GPAGPRGEKGEAALT 2786



 Score =  283 bits (724), Expect = 5e-76
 Identities = 181/431 (41%), Positives = 209/431 (48%), Gaps = 64/431 (14%)

Query: 515  PKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT---KGEPGKPGPPGDAGLQG 571
            PKG +G  G  G+ G  GP GD GLPG  G  G  G PG+   KGE G PG  G  G  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 572  LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV-GPRGPQGLPGSRGEL 630
              G PG PGA G+ G  G  G  G PG+ G  G  G+ G PG+V G  GP GLPG +G+ 
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP-GLPGRKGDP 1370

Query: 631  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP------KGEQGASGEE 684
            GP G PG  G LG  G  G PGLPG   + G KGDRG  G PGP       GE G  G  
Sbjct: 1371 GPSGPPGPRGPLGDPGPRGPPGLPGT-AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP 1429

Query: 685  GEAGERGELGDIGLPGPKGSA-----GNPGEPGLRGPEGSRGLPGVEGPRGP---PGPRG 736
            G  G +G +G  G  G KG +     G PG+PG  G +G RG PG  GP+G    PGP G
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489

Query: 737  VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 796
              GE+G  G PG  G  G                                G  G PG  G
Sbjct: 1490 EAGEKGERGPPGPAGSRGLP------------------------------GVAGRPGAKG 1519

Query: 797  PPGPPGPPGENGFPGQMGIRGLPGIKGPP--------GALGLRGPKGDLGEKGERGPPGR 848
            P GPPGP G  G  G+ G  G P + GP         G +G  GP+G  G +GERGPPG 
Sbjct: 1520 PEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL 1579

Query: 849  GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 908
               G PG  G PGD GP      G  G  GPPG +G PG  G PG PG PG   P     
Sbjct: 1580 VLPGDPGPKGDPGDRGPI-----GLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 909  QAGQRAFNKGP 919
            + G++  ++GP
Sbjct: 1635 EVGEKG-DEGP 1644


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  518 bits (1333), Expect = e-146
 Identities = 322/750 (42%), Positives = 365/750 (48%), Gaps = 120/750 (16%)

Query: 258  RITPSQTTDERGPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPG 305
            +I P       GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG
Sbjct: 815  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 874

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPG 356
              GE G  G  GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G
Sbjct: 875  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 934

Query: 357  R-------GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF----- 404
                    G  GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G      
Sbjct: 935  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 994

Query: 405  ---HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461
               H G P      PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GA
Sbjct: 995  ERGHPGPP-----GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1049

Query: 462  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGP 515
            QG PG +G  G  G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP
Sbjct: 1050 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1109

Query: 516  KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGL 572
            +G  G +G +G  GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG 
Sbjct: 1110 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1169

Query: 573  PGVPGIPGA---------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQ 608
             G PGI G          +G+ G+KG  GA               PG PG+ G +G  G 
Sbjct: 1170 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP 1229

Query: 609  QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------ 662
             GPPG  GPRGPQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      
Sbjct: 1230 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1289

Query: 663  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP------------------KGS 704
            +G++G  G PG  G  GA G  G+ G +G  G +G PG                   KG 
Sbjct: 1290 RGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1349

Query: 705  AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQ 760
             G+PG+PG  GP G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P   
Sbjct: 1350 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1409

Query: 761  HIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG 820
                       +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G
Sbjct: 1410 ------QGPAGKPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1462

Query: 821  IKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYG 869
             KG PG +GL GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G
Sbjct: 1463 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1522

Query: 870  RNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  GP G  G  G+PGPPG PG PG
Sbjct: 1523 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  516 bits (1328), Expect = e-146
 Identities = 315/721 (43%), Positives = 362/721 (50%), Gaps = 133/721 (18%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGD------RGPKGPPGPPGPAGEPGKPGAP----- 316
            RGPPG  G  G PGP G PG  G  G+      +GP+G  GPPGP G+PGK G P     
Sbjct: 540  RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 599

Query: 317  -GKPGTPGADGLTGPDGSPGSIGSKGQKGE------PGVPGS------------RGFPG- 356
             G PG PGA G  G DG PG  G KG +GE      PG PG             RG PG 
Sbjct: 600  RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 659

Query: 357  ---------RGIPGPPGPPGTAGL---PGELGRVGPVGD---PGRRGPPGPPGPPGPRGT 401
                     RG PG PG PG AG+   PG  G +GP G+   PG++G PGP G PGP+G 
Sbjct: 660  AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 719

Query: 402  IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE---GDQGELGE 458
            IG            PPG  G  G PG+ G  GA G  G PG++G  GE+   G  G  G 
Sbjct: 720  IG------------PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 767

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
            +G  GP G +G  G+ G+ G KGEKG  G  G  G  GL G  G+ GQ GP GE GP+G 
Sbjct: 768  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGP 827

Query: 519  RGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGV 575
            +G  G  G PG  G  G+ G  GV G  G PG  G KG    PG PG  G+ G +G+ G 
Sbjct: 828  KGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK 887

Query: 576  PGIPGAKGVAGEKGSTGA---PGKPGQMGNSGKPGQQGPPGEVGPRGPQ---GLPGSRGE 629
            PG  G +G  G +GS GA    GKPG  G SG  G  GPPGE GP+GPQ   G PG +G 
Sbjct: 888  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 947

Query: 630  LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------------PGPKGE 677
             GP G  GLPG  G  G  G  G  GPPG  G+ G +G  GE            PGP GE
Sbjct: 948  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 1007

Query: 678  Q---GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            Q   GA+G+EG  G+ G  G  G  GP G  G PGE GL G +G+ GL G EGP+GPPGP
Sbjct: 1008 QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1067

Query: 735  RGVQGEQGATGL---------PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
             G  GE+G+ G          PG QGPPG A                             
Sbjct: 1068 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------------------- 1098

Query: 786  SGATGLPGRPGPPGPPGPPGEN---GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
             G  G PG  GP GP G  G     G PG  G  G PG  G  G +G  G KG  G+KGE
Sbjct: 1099 -GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1157

Query: 843  RGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLP 898
             GPPG    +GP G PG  G  G+PGP   G+ G  G++G  G  G PG PGP G  GLP
Sbjct: 1158 NGPPGPPGLQGPVGAPGIAGGDGEPGPR--GQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1215

Query: 899  G 899
            G
Sbjct: 1216 G 1216



 Score =  511 bits (1316), Expect = e-144
 Identities = 320/774 (41%), Positives = 375/774 (48%), Gaps = 171/774 (22%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG PG PG   
Sbjct: 623  DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG--- 679

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP------------PGTAGLPG 373
            + G DG PG  G+ G +GEPG PG +G PG +G+PGP GP            PG AGLPG
Sbjct: 680  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 739

Query: 374  ------ELGRVGPVGDPGRRGPPGPPGP---PGPRGTIGFHDGDPLCPNACPPGRSGYPG 424
                    G+ G  G+ G  GPPGP GP   PGPRG  G      L  +    G  G+PG
Sbjct: 740  ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799

Query: 425  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP------------------PG 466
              G  G KG +GE+G+ G +G  G EG +G  G  G  GP                  PG
Sbjct: 800  FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859

Query: 467  AQGLRGITGIVG---DKGEKGARGLDGEPGPQGLPGAPGDQGQRG---PPGEAGPKG--- 517
             QG +G TG  G     GEKGARG+ G+PGP+G  G  G +G RG   P G+ GPKG   
Sbjct: 860  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919

Query: 518  ---------DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
                     +RG +G +G  G PGPKG  G PG DG  G PG  G  G  GK GPPG  G
Sbjct: 920  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 979

Query: 569  L---------------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK-------- 605
            +               +G PG PG PG +G+ G  G  GA G PG  G SGK        
Sbjct: 980  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039

Query: 606  -PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG++G PG  G  G +G  G +G  GPVGSPG  G  G+ G  GLPG PGP G PG  G
Sbjct: 1040 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1099

Query: 665  DRGVVGE------------------PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706
            ++G  GE                  PGP G  G+ GE+G+ GE GE G  G  G KG  G
Sbjct: 1100 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1159

Query: 707  NPGEPGLRGPEGSRGLPGVEG---PRG------------------PPGPRGVQ------G 739
             PG PGL+GP G+ G+ G +G   PRG                  PPGP G+Q      G
Sbjct: 1160 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 740  EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
            E+G  G  G  GPPG                                G  G  G  GP G
Sbjct: 1220 EKGENGDVGPMGPPG---------------------------PPGPRGPQGPNGADGPQG 1252

Query: 800  PPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----------- 848
            PPG  G  G  G+ G  G  G  GPPG  G+ GPKG+ GEKGE GPPG            
Sbjct: 1253 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1312

Query: 849  --GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              GP G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1313 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1366



 Score =  505 bits (1301), Expect = e-143
 Identities = 302/711 (42%), Positives = 349/711 (49%), Gaps = 110/711 (15%)

Query: 267  ERGPPGE----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316
            E+G  GE          +GPPGP GP G+          GP G  GP GP G+PG  G P
Sbjct: 436  EKGQKGEPAVVEPGMLVEGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPP 486

Query: 317  GKPGTPGADGLTGPDGS----PGSIGSKGQKGEP--------------------GVPGSR 352
            G+PG PGADGL GP G+    P   G  G KG                      G PG  
Sbjct: 487  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 546

Query: 353  GFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PL 410
            G  GR  PGP G PG++G  GE G  GP G  G +GPPGP G PG RG  G   G   P 
Sbjct: 547  GLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 604

Query: 411  CPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE----------- 458
             P A    G  G PGLPG +GH+G +G  G PG  G  G  G+ GE+G            
Sbjct: 605  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664

Query: 459  -VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG 517
             +G +G PGA G  G+ G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G
Sbjct: 665  LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 724

Query: 518  DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
            ++G +G  G+ GLPG  G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G
Sbjct: 725  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 784

Query: 578  IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            + G+KG  GE G  G  G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G
Sbjct: 785  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 844

Query: 638  LPGKLGSLGSPGLPGLPGP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              GKLG  G PG PG  GP         PG  G KG RGV G+PGP+G++G +G  G  G
Sbjct: 845  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 904

Query: 689  ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQG 742
             RG  G  G  G  G  G PG PG RGP+G +G  G  GP+GPPGP G        G++G
Sbjct: 905  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 964

Query: 743  ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802
             TG  G  GPPG                            +  +G TG  G  G PGPPG
Sbjct: 965  ETGFQGKTGPPGPG---------------------GVVGPQGPTGETGPIGERGHPGPPG 1003

Query: 803  PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNG 852
            PPGE G PG  G  G  G  GP G  G  GP G  G  GERG P          G GP G
Sbjct: 1004 PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063

Query: 853  LPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             PG +G PG+ G A      G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1064 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1114



 Score =  454 bits (1169), Expect = e-127
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 312  KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 404  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 459

Query: 367  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 408
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 460  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 519

Query: 409  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 450
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 520  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 579

Query: 451  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 501
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 580  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 639

Query: 502  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 640  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 699

Query: 559  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 700  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759

Query: 616  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 675
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 760  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 676  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 717
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 820  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 718  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 777
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 880  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 924

Query: 778  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 834
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 925  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 984

Query: 835  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 877
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 985  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1044

Query: 878  GPPGVAGIPGVPGPPGPPGLPG 899
            G PG  G PG+ G  GP G PG
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPG 1066



 Score =  288 bits (738), Expect = 1e-77
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 475 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 432 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 481

Query: 533 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 577
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 482 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 541

Query: 578 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 542 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 601

Query: 638 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 602 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 655

Query: 698 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 757
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 656 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 711

Query: 758 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 712 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 736

Query: 818 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 864
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 737 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 793

Query: 865 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 794 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846



 Score =  217 bits (553), Expect = 3e-56
 Identities = 158/424 (37%), Positives = 183/424 (43%), Gaps = 89/424 (20%)

Query: 542 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 587
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 377 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 436

Query: 588 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 645
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 437 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 489

Query: 646 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 678
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 490 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 549

Query: 679 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 738
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 609

Query: 739 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 798
           G++G  GLPG+ G  G                  H  E          G  G+ G  G  
Sbjct: 610 GDRGFDGLPGLPGDKG------------------HRGERGPQGPPGPPGDDGMRGEDGEI 651

Query: 799 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP---KGDLGEKGERGPPGR----GPN 851
           GP G PGE G  G +G RG PG  G PG  G+ GP   KG++G +GE GPPG+    GP 
Sbjct: 652 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 711

Query: 852 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP------------GPPGPPGLPG 899
           GLPG  G  G PG    G  G+ G  G PG  G PG P            GPPGP G  G
Sbjct: 712 GLPGPQGPIGPPGEK--GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 769

Query: 900 FCEP 903
           +  P
Sbjct: 770 YPGP 773



 Score =  181 bits (460), Expect = 2e-45
 Identities = 113/257 (43%), Positives = 124/257 (48%), Gaps = 35/257 (13%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    P+      G  GE G PG PGPP         G  G  GPPGPPG  G PG  GA
Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPP---------GPSGEAGPPGPPGKRGPPGAAGA 1382

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375
             G+ G  GA G  G +G PG  G  G +G  G PG  G   RGI   PGP G  GLPG  
Sbjct: 1383 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL--RGI---PGPVGEQGLPGAA 1437

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G+ GP   PG  GPPG PG  G  G+ G              G  G  GL G  G +G K
Sbjct: 1438 GQDGP---PGPMGPPGLPGLKGDPGSKG------------EKGHPGLIGLIGPPGEQGEK 1482

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
            G+ G PG QG  G +GD G  G  G  GPPG  GL    G  G KG KG+ G  G+ G  
Sbjct: 1483 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAGQKGDS 1539

Query: 496  GLPGAPGDQGQRGPPGE 512
            GLPG PG     GPPGE
Sbjct: 1540 GLPGPPGSP---GPPGE 1553



 Score =  153 bits (386), Expect = 8e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 636 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 686
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 415 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 470

Query: 687 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 728
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 471 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 530

Query: 729 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 779
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 531 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 568

Query: 780 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 836
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 569 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623

Query: 837 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 889
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 624 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 890 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G  GPPG  G   P       GQ+  N GP
Sbjct: 682 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 710



 Score =  113 bits (283), Expect = 7e-25
 Identities = 64/157 (40%), Positives = 72/157 (45%), Gaps = 17/157 (10%)

Query: 246  RPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG 305
            +P  E    +P  +         G  G  GP GPPG PG+                G PG
Sbjct: 1415 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL---------------KGDPG 1459

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP 365
              GE G PG  G  G PG  G  G  G PG+ GS G KG+ G+PG  G    G PGPPG 
Sbjct: 1460 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPGPPGL 1517

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTI 402
            PG  G  G  G  GP G  G  G PGPPG PGP G +
Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554



 Score =  108 bits (269), Expect = 3e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 325
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1435 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1494

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 375
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1495 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554

Query: 376  GRVGPV 381
             +  P+
Sbjct: 1555 IQPLPI 1560



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 12/164 (7%)

Query: 86  AYKLGNNVDFRIPTRNLYPSG-LPEEYSFLTTFRMTGSTLKKNWN--IWQIQDSSGKEQV 142
           AY++        PT+ L+P G  PE++S L T +      KK     +  I +  G +Q+
Sbjct: 73  AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKP-----KKGIQSFLLSIYNEHGIQQI 127

Query: 143 GIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIE 202
           G+++      +   + G         F  ++ + D +WH++ I VE+ + T+ VDC +  
Sbjct: 128 GVEVGRSPVFLFEDHTGKPAPEDYPLFRTVN-IADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 203 SLPI--KPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLIHCDP 244
           + P+    R  +D +G  V G    + +V    ++Q  LI  DP
Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRILDEEV-FEGDIQQFLITGDP 229


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  518 bits (1333), Expect = e-146
 Identities = 322/750 (42%), Positives = 365/750 (48%), Gaps = 120/750 (16%)

Query: 258  RITPSQTTDERGPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPG 305
            +I P       GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG
Sbjct: 764  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPG 356
              GE G  G  GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G
Sbjct: 824  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 883

Query: 357  R-------GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF----- 404
                    G  GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G      
Sbjct: 884  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 943

Query: 405  ---HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461
               H G P      PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GA
Sbjct: 944  ERGHPGPP-----GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 998

Query: 462  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGP 515
            QG PG +G  G  G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP
Sbjct: 999  QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1058

Query: 516  KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGL 572
            +G  G +G +G  GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG 
Sbjct: 1059 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1118

Query: 573  PGVPGIPGA---------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQ 608
             G PGI G          +G+ G+KG  GA               PG PG+ G +G  G 
Sbjct: 1119 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP 1178

Query: 609  QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------ 662
             GPPG  GPRGPQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      
Sbjct: 1179 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1238

Query: 663  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP------------------KGS 704
            +G++G  G PG  G  GA G  G+ G +G  G +G PG                   KG 
Sbjct: 1239 RGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1298

Query: 705  AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQ 760
             G+PG+PG  GP G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P   
Sbjct: 1299 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1358

Query: 761  HIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG 820
                       +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G
Sbjct: 1359 ------QGPAGKPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1411

Query: 821  IKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYG 869
             KG PG +GL GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G
Sbjct: 1412 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1471

Query: 870  RNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  GP G  G  G+PGPPG PG PG
Sbjct: 1472 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  516 bits (1328), Expect = e-146
 Identities = 315/721 (43%), Positives = 362/721 (50%), Gaps = 133/721 (18%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGD------RGPKGPPGPPGPAGEPGKPGAP----- 316
            RGPPG  G  G PGP G PG  G  G+      +GP+G  GPPGP G+PGK G P     
Sbjct: 489  RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 548

Query: 317  -GKPGTPGADGLTGPDGSPGSIGSKGQKGE------PGVPGS------------RGFPG- 356
             G PG PGA G  G DG PG  G KG +GE      PG PG             RG PG 
Sbjct: 549  RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 608

Query: 357  ---------RGIPGPPGPPGTAGL---PGELGRVGPVGD---PGRRGPPGPPGPPGPRGT 401
                     RG PG PG PG AG+   PG  G +GP G+   PG++G PGP G PGP+G 
Sbjct: 609  AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 668

Query: 402  IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE---GDQGELGE 458
            IG            PPG  G  G PG+ G  GA G  G PG++G  GE+   G  G  G 
Sbjct: 669  IG------------PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 716

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
            +G  GP G +G  G+ G+ G KGEKG  G  G  G  GL G  G+ GQ GP GE GP+G 
Sbjct: 717  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGP 776

Query: 519  RGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGV 575
            +G  G  G PG  G  G+ G  GV G  G PG  G KG    PG PG  G+ G +G+ G 
Sbjct: 777  KGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK 836

Query: 576  PGIPGAKGVAGEKGSTGA---PGKPGQMGNSGKPGQQGPPGEVGPRGPQ---GLPGSRGE 629
            PG  G +G  G +GS GA    GKPG  G SG  G  GPPGE GP+GPQ   G PG +G 
Sbjct: 837  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 896

Query: 630  LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------------PGPKGE 677
             GP G  GLPG  G  G  G  G  GPPG  G+ G +G  GE            PGP GE
Sbjct: 897  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 956

Query: 678  Q---GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            Q   GA+G+EG  G+ G  G  G  GP G  G PGE GL G +G+ GL G EGP+GPPGP
Sbjct: 957  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016

Query: 735  RGVQGEQGATGL---------PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
             G  GE+G+ G          PG QGPPG A                             
Sbjct: 1017 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------------------- 1047

Query: 786  SGATGLPGRPGPPGPPGPPGEN---GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
             G  G PG  GP GP G  G     G PG  G  G PG  G  G +G  G KG  G+KGE
Sbjct: 1048 -GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1106

Query: 843  RGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLP 898
             GPPG    +GP G PG  G  G+PGP   G+ G  G++G  G  G PG PGP G  GLP
Sbjct: 1107 NGPPGPPGLQGPVGAPGIAGGDGEPGPR--GQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1164

Query: 899  G 899
            G
Sbjct: 1165 G 1165



 Score =  511 bits (1316), Expect = e-144
 Identities = 320/774 (41%), Positives = 375/774 (48%), Gaps = 171/774 (22%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG PG PG   
Sbjct: 572  DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG--- 628

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP------------PGTAGLPG 373
            + G DG PG  G+ G +GEPG PG +G PG +G+PGP GP            PG AGLPG
Sbjct: 629  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 688

Query: 374  ------ELGRVGPVGDPGRRGPPGPPGP---PGPRGTIGFHDGDPLCPNACPPGRSGYPG 424
                    G+ G  G+ G  GPPGP GP   PGPRG  G      L  +    G  G+PG
Sbjct: 689  ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 748

Query: 425  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP------------------PG 466
              G  G KG +GE+G+ G +G  G EG +G  G  G  GP                  PG
Sbjct: 749  FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 808

Query: 467  AQGLRGITGIVG---DKGEKGARGLDGEPGPQGLPGAPGDQGQRG---PPGEAGPKG--- 517
             QG +G TG  G     GEKGARG+ G+PGP+G  G  G +G RG   P G+ GPKG   
Sbjct: 809  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868

Query: 518  ---------DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
                     +RG +G +G  G PGPKG  G PG DG  G PG  G  G  GK GPPG  G
Sbjct: 869  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 928

Query: 569  L---------------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK-------- 605
            +               +G PG PG PG +G+ G  G  GA G PG  G SGK        
Sbjct: 929  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988

Query: 606  -PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG++G PG  G  G +G  G +G  GPVGSPG  G  G+ G  GLPG PGP G PG  G
Sbjct: 989  FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1048

Query: 665  DRGVVGE------------------PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706
            ++G  GE                  PGP G  G+ GE+G+ GE GE G  G  G KG  G
Sbjct: 1049 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1108

Query: 707  NPGEPGLRGPEGSRGLPGVEG---PRG------------------PPGPRGVQ------G 739
             PG PGL+GP G+ G+ G +G   PRG                  PPGP G+Q      G
Sbjct: 1109 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 740  EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
            E+G  G  G  GPPG                                G  G  G  GP G
Sbjct: 1169 EKGENGDVGPMGPPG---------------------------PPGPRGPQGPNGADGPQG 1201

Query: 800  PPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----------- 848
            PPG  G  G  G+ G  G  G  GPPG  G+ GPKG+ GEKGE GPPG            
Sbjct: 1202 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1261

Query: 849  --GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              GP G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1262 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1315



 Score =  505 bits (1301), Expect = e-143
 Identities = 302/711 (42%), Positives = 349/711 (49%), Gaps = 110/711 (15%)

Query: 267  ERGPPGE----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316
            E+G  GE          +GPPGP GP G+          GP G  GP GP G+PG  G P
Sbjct: 385  EKGQKGEPAVVEPGMLVEGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPP 435

Query: 317  GKPGTPGADGLTGPDGS----PGSIGSKGQKGEP--------------------GVPGSR 352
            G+PG PGADGL GP G+    P   G  G KG                      G PG  
Sbjct: 436  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 495

Query: 353  GFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PL 410
            G  GR  PGP G PG++G  GE G  GP G  G +GPPGP G PG RG  G   G   P 
Sbjct: 496  GLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 553

Query: 411  CPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE----------- 458
             P A    G  G PGLPG +GH+G +G  G PG  G  G  G+ GE+G            
Sbjct: 554  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613

Query: 459  -VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG 517
             +G +G PGA G  G+ G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G
Sbjct: 614  LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 673

Query: 518  DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
            ++G +G  G+ GLPG  G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G
Sbjct: 674  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 733

Query: 578  IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            + G+KG  GE G  G  G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G
Sbjct: 734  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 793

Query: 638  LPGKLGSLGSPGLPGLPGP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              GKLG  G PG PG  GP         PG  G KG RGV G+PGP+G++G +G  G  G
Sbjct: 794  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 853

Query: 689  ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQG 742
             RG  G  G  G  G  G PG PG RGP+G +G  G  GP+GPPGP G        G++G
Sbjct: 854  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 913

Query: 743  ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802
             TG  G  GPPG                            +  +G TG  G  G PGPPG
Sbjct: 914  ETGFQGKTGPPGPG---------------------GVVGPQGPTGETGPIGERGHPGPPG 952

Query: 803  PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNG 852
            PPGE G PG  G  G  G  GP G  G  GP G  G  GERG P          G GP G
Sbjct: 953  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012

Query: 853  LPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             PG +G PG+ G A      G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1013 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063



 Score =  454 bits (1169), Expect = e-127
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 312  KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 353  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 408

Query: 367  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 408
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 409  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 468

Query: 409  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 450
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 469  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 528

Query: 451  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 501
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 529  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 588

Query: 502  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 589  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 648

Query: 559  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 649  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708

Query: 616  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 675
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 709  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 676  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 717
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 769  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 718  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 777
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 829  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 873

Query: 778  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 834
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933

Query: 835  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 877
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 878  GPPGVAGIPGVPGPPGPPGLPG 899
            G PG  G PG+ G  GP G PG
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPG 1015



 Score =  288 bits (738), Expect = 1e-77
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 475 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 381 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 430

Query: 533 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 577
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 431 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 490

Query: 578 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 491 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 550

Query: 638 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 551 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 604

Query: 698 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 757
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 605 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 660

Query: 758 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 661 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 685

Query: 818 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 864
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 686 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 742

Query: 865 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 743 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 795



 Score =  217 bits (553), Expect = 3e-56
 Identities = 158/424 (37%), Positives = 183/424 (43%), Gaps = 89/424 (20%)

Query: 542 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 587
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 326 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 385

Query: 588 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 645
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 386 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 438

Query: 646 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 678
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 439 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 498

Query: 679 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 738
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 558

Query: 739 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 798
           G++G  GLPG+ G  G                  H  E          G  G+ G  G  
Sbjct: 559 GDRGFDGLPGLPGDKG------------------HRGERGPQGPPGPPGDDGMRGEDGEI 600

Query: 799 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP---KGDLGEKGERGPPGR----GPN 851
           GP G PGE G  G +G RG PG  G PG  G+ GP   KG++G +GE GPPG+    GP 
Sbjct: 601 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 660

Query: 852 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP------------GPPGPPGLPG 899
           GLPG  G  G PG    G  G+ G  G PG  G PG P            GPPGP G  G
Sbjct: 661 GLPGPQGPIGPPGEK--GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 718

Query: 900 FCEP 903
           +  P
Sbjct: 719 YPGP 722



 Score =  181 bits (460), Expect = 2e-45
 Identities = 113/257 (43%), Positives = 124/257 (48%), Gaps = 35/257 (13%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    P+      G  GE G PG PGPP         G  G  GPPGPPG  G PG  GA
Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPP---------GPSGEAGPPGPPGKRGPPGAAGA 1331

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375
             G+ G  GA G  G +G PG  G  G +G  G PG  G   RGI   PGP G  GLPG  
Sbjct: 1332 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL--RGI---PGPVGEQGLPGAA 1386

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G+ GP   PG  GPPG PG  G  G+ G              G  G  GL G  G +G K
Sbjct: 1387 GQDGP---PGPMGPPGLPGLKGDPGSKG------------EKGHPGLIGLIGPPGEQGEK 1431

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
            G+ G PG QG  G +GD G  G  G  GPPG  GL    G  G KG KG+ G  G+ G  
Sbjct: 1432 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAGQKGDS 1488

Query: 496  GLPGAPGDQGQRGPPGE 512
            GLPG PG     GPPGE
Sbjct: 1489 GLPGPPGSP---GPPGE 1502



 Score =  153 bits (386), Expect = 8e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 636 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 686
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 364 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 419

Query: 687 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 728
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 420 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479

Query: 729 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 779
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 517

Query: 780 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 836
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 518 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572

Query: 837 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 889
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 573 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 890 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G  GPPG  G   P       GQ+  N GP
Sbjct: 631 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 659



 Score =  113 bits (283), Expect = 7e-25
 Identities = 64/157 (40%), Positives = 72/157 (45%), Gaps = 17/157 (10%)

Query: 246  RPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG 305
            +P  E    +P  +         G  G  GP GPPG PG+                G PG
Sbjct: 1364 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL---------------KGDPG 1408

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP 365
              GE G PG  G  G PG  G  G  G PG+ GS G KG+ G+PG  G    G PGPPG 
Sbjct: 1409 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPGPPGL 1466

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTI 402
            PG  G  G  G  GP G  G  G PGPPG PGP G +
Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503



 Score =  108 bits (269), Expect = 3e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 325
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 375
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1444 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503

Query: 376  GRVGPV 381
             +  P+
Sbjct: 1504 IQPLPI 1509



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 12/164 (7%)

Query: 86  AYKLGNNVDFRIPTRNLYPSG-LPEEYSFLTTFRMTGSTLKKNWN--IWQIQDSSGKEQV 142
           AY++        PT+ L+P G  PE++S L T +      KK     +  I +  G +Q+
Sbjct: 73  AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKP-----KKGIQSFLLSIYNEHGIQQI 127

Query: 143 GIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIE 202
           G+++      +   + G         F  ++ + D +WH++ I VE+ + T+ VDC +  
Sbjct: 128 GVEVGRSPVFLFEDHTGKPAPEDYPLFRTVN-IADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 203 SLPI--KPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLIHCDP 244
           + P+    R  +D +G  V G    + +V    ++Q  LI  DP
Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRILDEEV-FEGDIQQFLITGDP 229


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  518 bits (1333), Expect = e-146
 Identities = 322/750 (42%), Positives = 365/750 (48%), Gaps = 120/750 (16%)

Query: 258  RITPSQTTDERGPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPG 305
            +I P       GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG
Sbjct: 803  QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 862

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPG 356
              GE G  G  GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G
Sbjct: 863  ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 922

Query: 357  R-------GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF----- 404
                    G  GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G      
Sbjct: 923  PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 982

Query: 405  ---HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461
               H G P      PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GA
Sbjct: 983  ERGHPGPP-----GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGA 1037

Query: 462  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGP 515
            QG PG +G  G  G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP
Sbjct: 1038 QGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGP 1097

Query: 516  KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGL 572
            +G  G +G +G  GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG 
Sbjct: 1098 QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP 1157

Query: 573  PGVPGIPGA---------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQ 608
             G PGI G          +G+ G+KG  GA               PG PG+ G +G  G 
Sbjct: 1158 VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGP 1217

Query: 609  QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------ 662
             GPPG  GPRGPQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      
Sbjct: 1218 MGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGE 1277

Query: 663  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP------------------KGS 704
            +G++G  G PG  G  GA G  G+ G +G  G +G PG                   KG 
Sbjct: 1278 RGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGE 1337

Query: 705  AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQ 760
             G+PG+PG  GP G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P   
Sbjct: 1338 DGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP 1397

Query: 761  HIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG 820
                       +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G
Sbjct: 1398 ------QGPAGKPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKG 1450

Query: 821  IKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYG 869
             KG PG +GL GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G
Sbjct: 1451 EKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQG 1510

Query: 870  RNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  GP G  G  G+PGPPG PG PG
Sbjct: 1511 PKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  516 bits (1328), Expect = e-146
 Identities = 315/721 (43%), Positives = 362/721 (50%), Gaps = 133/721 (18%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGD------RGPKGPPGPPGPAGEPGKPGAP----- 316
            RGPPG  G  G PGP G PG  G  G+      +GP+G  GPPGP G+PGK G P     
Sbjct: 528  RGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGG 587

Query: 317  -GKPGTPGADGLTGPDGSPGSIGSKGQKGE------PGVPGS------------RGFPG- 356
             G PG PGA G  G DG PG  G KG +GE      PG PG             RG PG 
Sbjct: 588  RGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGE 647

Query: 357  ---------RGIPGPPGPPGTAGL---PGELGRVGPVGD---PGRRGPPGPPGPPGPRGT 401
                     RG PG PG PG AG+   PG  G +GP G+   PG++G PGP G PGP+G 
Sbjct: 648  AGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGP 707

Query: 402  IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE---GDQGELGE 458
            IG            PPG  G  G PG+ G  GA G  G PG++G  GE+   G  G  G 
Sbjct: 708  IG------------PPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGP 755

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
            +G  GP G +G  G+ G+ G KGEKG  G  G  G  GL G  G+ GQ GP GE GP+G 
Sbjct: 756  IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGP 815

Query: 519  RGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGV 575
            +G  G  G PG  G  G+ G  GV G  G PG  G KG    PG PG  G+ G +G+ G 
Sbjct: 816  KGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGK 875

Query: 576  PGIPGAKGVAGEKGSTGA---PGKPGQMGNSGKPGQQGPPGEVGPRGPQ---GLPGSRGE 629
            PG  G +G  G +GS GA    GKPG  G SG  G  GPPGE GP+GPQ   G PG +G 
Sbjct: 876  PGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP 935

Query: 630  LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------------PGPKGE 677
             GP G  GLPG  G  G  G  G  GPPG  G+ G +G  GE            PGP GE
Sbjct: 936  PGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGE 995

Query: 678  Q---GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 734
            Q   GA+G+EG  G+ G  G  G  GP G  G PGE GL G +G+ GL G EGP+GPPGP
Sbjct: 996  QGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055

Query: 735  RGVQGEQGATGL---------PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 785
             G  GE+G+ G          PG QGPPG A                             
Sbjct: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPA----------------------------- 1086

Query: 786  SGATGLPGRPGPPGPPGPPGEN---GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 842
             G  G PG  GP GP G  G     G PG  G  G PG  G  G +G  G KG  G+KGE
Sbjct: 1087 -GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGE 1145

Query: 843  RGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLP 898
             GPPG    +GP G PG  G  G+PGP   G+ G  G++G  G  G PG PGP G  GLP
Sbjct: 1146 NGPPGPPGLQGPVGAPGIAGGDGEPGPR--GQQGMFGQKGDEGARGFPGPPGPIGLQGLP 1203

Query: 899  G 899
            G
Sbjct: 1204 G 1204



 Score =  511 bits (1316), Expect = e-144
 Identities = 320/774 (41%), Positives = 375/774 (48%), Gaps = 171/774 (22%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            ++G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG PG PG   
Sbjct: 611  DKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPG--- 667

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP------------PGTAGLPG 373
            + G DG PG  G+ G +GEPG PG +G PG +G+PGP GP            PG AGLPG
Sbjct: 668  MAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG 727

Query: 374  ------ELGRVGPVGDPGRRGPPGPPGP---PGPRGTIGFHDGDPLCPNACPPGRSGYPG 424
                    G+ G  G+ G  GPPGP GP   PGPRG  G      L  +    G  G+PG
Sbjct: 728  ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787

Query: 425  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP------------------PG 466
              G  G KG +GE+G+ G +G  G EG +G  G  G  GP                  PG
Sbjct: 788  FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 847

Query: 467  AQGLRGITGIVG---DKGEKGARGLDGEPGPQGLPGAPGDQGQRG---PPGEAGPKG--- 517
             QG +G TG  G     GEKGARG+ G+PGP+G  G  G +G RG   P G+ GPKG   
Sbjct: 848  RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907

Query: 518  ---------DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
                     +RG +G +G  G PGPKG  G PG DG  G PG  G  G  GK GPPG  G
Sbjct: 908  GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 967

Query: 569  L---------------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK-------- 605
            +               +G PG PG PG +G+ G  G  GA G PG  G SGK        
Sbjct: 968  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027

Query: 606  -PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 664
             PG++G PG  G  G +G  G +G  GPVGSPG  G  G+ G  GLPG PGP G PG  G
Sbjct: 1028 FPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAG 1087

Query: 665  DRGVVGE------------------PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG 706
            ++G  GE                  PGP G  G+ GE+G+ GE GE G  G  G KG  G
Sbjct: 1088 EKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG 1147

Query: 707  NPGEPGLRGPEGSRGLPGVEG---PRG------------------PPGPRGVQ------G 739
             PG PGL+GP G+ G+ G +G   PRG                  PPGP G+Q      G
Sbjct: 1148 PPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 740  EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
            E+G  G  G  GPPG                                G  G  G  GP G
Sbjct: 1208 EKGENGDVGPMGPPG---------------------------PPGPRGPQGPNGADGPQG 1240

Query: 800  PPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----------- 848
            PPG  G  G  G+ G  G  G  GPPG  G+ GPKG+ GEKGE GPPG            
Sbjct: 1241 PPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1300

Query: 849  --GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              GP G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1301 DDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1354



 Score =  505 bits (1301), Expect = e-143
 Identities = 302/711 (42%), Positives = 349/711 (49%), Gaps = 110/711 (15%)

Query: 267  ERGPPGE----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 316
            E+G  GE          +GPPGP GP G+          GP G  GP GP G+PG  G P
Sbjct: 424  EKGQKGEPAVVEPGMLVEGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPP 474

Query: 317  GKPGTPGADGLTGPDGS----PGSIGSKGQKGEP--------------------GVPGSR 352
            G+PG PGADGL GP G+    P   G  G KG                      G PG  
Sbjct: 475  GRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPM 534

Query: 353  GFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PL 410
            G  GR  PGP G PG++G  GE G  GP G  G +GPPGP G PG RG  G   G   P 
Sbjct: 535  GLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPG 592

Query: 411  CPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE----------- 458
             P A    G  G PGLPG +GH+G +G  G PG  G  G  G+ GE+G            
Sbjct: 593  EPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652

Query: 459  -VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG 517
             +G +G PGA G  G+ G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G
Sbjct: 653  LLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 712

Query: 518  DRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 577
            ++G +G  G+ GLPG  G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G
Sbjct: 713  EKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRG 772

Query: 578  IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            + G+KG  GE G  G  G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G
Sbjct: 773  LKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAG 832

Query: 638  LPGKLGSLGSPGLPGLPGP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              GKLG  G PG PG  GP         PG  G KG RGV G+PGP+G++G +G  G  G
Sbjct: 833  EKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRG 892

Query: 689  ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQG 742
             RG  G  G  G  G  G PG PG RGP+G +G  G  GP+GPPGP G        G++G
Sbjct: 893  ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRG 952

Query: 743  ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 802
             TG  G  GPPG                            +  +G TG  G  G PGPPG
Sbjct: 953  ETGFQGKTGPPGPG---------------------GVVGPQGPTGETGPIGERGHPGPPG 991

Query: 803  PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNG 852
            PPGE G PG  G  G  G  GP G  G  GP G  G  GERG P          G GP G
Sbjct: 992  PPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051

Query: 853  LPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             PG +G PG+ G A      G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1052 PPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102



 Score =  454 bits (1169), Expect = e-127
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 312  KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 392  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 447

Query: 367  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 408
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 448  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 507

Query: 409  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 450
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 508  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 567

Query: 451  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 501
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 568  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 627

Query: 502  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 628  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 687

Query: 559  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 615
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 688  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747

Query: 616  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 675
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 748  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 676  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 717
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 808  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 718  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 777
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 868  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 912

Query: 778  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 834
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 913  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 972

Query: 835  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 877
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 973  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1032

Query: 878  GPPGVAGIPGVPGPPGPPGLPG 899
            G PG  G PG+ G  GP G PG
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPG 1054



 Score =  288 bits (738), Expect = 1e-77
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 475 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 532
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 420 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 469

Query: 533 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 577
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 470 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 529

Query: 578 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 637
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 530 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 589

Query: 638 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 697
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 590 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 643

Query: 698 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 757
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 644 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 699

Query: 758 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 700 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 724

Query: 818 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 864
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 725 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 781

Query: 865 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 782 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 834



 Score =  217 bits (553), Expect = 3e-56
 Identities = 158/424 (37%), Positives = 183/424 (43%), Gaps = 89/424 (20%)

Query: 542 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 587
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 365 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 424

Query: 588 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 645
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 425 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 477

Query: 646 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 678
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 478 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 537

Query: 679 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 738
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 538 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597

Query: 739 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 798
           G++G  GLPG+ G  G                  H  E          G  G+ G  G  
Sbjct: 598 GDRGFDGLPGLPGDKG------------------HRGERGPQGPPGPPGDDGMRGEDGEI 639

Query: 799 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP---KGDLGEKGERGPPGR----GPN 851
           GP G PGE G  G +G RG PG  G PG  G+ GP   KG++G +GE GPPG+    GP 
Sbjct: 640 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ 699

Query: 852 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVP------------GPPGPPGLPG 899
           GLPG  G  G PG    G  G+ G  G PG  G PG P            GPPGP G  G
Sbjct: 700 GLPGPQGPIGPPGEK--GPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIG 757

Query: 900 FCEP 903
           +  P
Sbjct: 758 YPGP 761



 Score =  181 bits (460), Expect = 2e-45
 Identities = 113/257 (43%), Positives = 124/257 (48%), Gaps = 35/257 (13%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 315
            P    P+      G  GE G PG PGPP         G  G  GPPGPPG  G PG  GA
Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPP---------GPSGEAGPPGPPGKRGPPGAAGA 1370

Query: 316  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGEL 375
             G+ G  GA G  G +G PG  G  G +G  G PG  G   RGI   PGP G  GLPG  
Sbjct: 1371 EGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGL--RGI---PGPVGEQGLPGAA 1425

Query: 376  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 435
            G+ GP   PG  GPPG PG  G  G+ G              G  G  GL G  G +G K
Sbjct: 1426 GQDGP---PGPMGPPGLPGLKGDPGSKG------------EKGHPGLIGLIGPPGEQGEK 1470

Query: 436  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 495
            G+ G PG QG  G +GD G  G  G  GPPG  GL    G  G KG KG+ G  G+ G  
Sbjct: 1471 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL---PGPQGPKGNKGSTGPAGQKGDS 1527

Query: 496  GLPGAPGDQGQRGPPGE 512
            GLPG PG     GPPGE
Sbjct: 1528 GLPGPPGSP---GPPGE 1541



 Score =  153 bits (386), Expect = 8e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 636 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 686
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 403 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 458

Query: 687 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 728
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 459 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 518

Query: 729 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 779
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 519 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 556

Query: 780 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 836
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 557 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611

Query: 837 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 889
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 612 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 890 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
           G  GPPG  G   P       GQ+  N GP
Sbjct: 670 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 698



 Score =  113 bits (283), Expect = 7e-25
 Identities = 64/157 (40%), Positives = 72/157 (45%), Gaps = 17/157 (10%)

Query: 246  RPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG 305
            +P  E    +P  +         G  G  GP GPPG PG+                G PG
Sbjct: 1403 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL---------------KGDPG 1447

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP 365
              GE G PG  G  G PG  G  G  G PG+ GS G KG+ G+PG  G    G PGPPG 
Sbjct: 1448 SKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAG--PLGPPGPPGL 1505

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTI 402
            PG  G  G  G  GP G  G  G PGPPG PGP G +
Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542



 Score =  108 bits (269), Expect = 3e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 325
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482

Query: 326  GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 375
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1483 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542

Query: 376  GRVGPV 381
             +  P+
Sbjct: 1543 IQPLPI 1548



 Score = 60.1 bits (144), Expect = 9e-09
 Identities = 42/164 (25%), Positives = 76/164 (46%), Gaps = 12/164 (7%)

Query: 86  AYKLGNNVDFRIPTRNLYPSG-LPEEYSFLTTFRMTGSTLKKNWN--IWQIQDSSGKEQV 142
           AY++        PT+ L+P G  PE++S L T +      KK     +  I +  G +Q+
Sbjct: 73  AYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKP-----KKGIQSFLLSIYNEHGIQQI 127

Query: 143 GIKINGQTQSVVFSYKGLDGSLQTAAFSNLSSLFDSQWHKIMIGVERSSATLFVDCNRIE 202
           G+++      +   + G         F  ++ + D +WH++ I VE+ + T+ VDC +  
Sbjct: 128 GVEVGRSPVFLFEDHTGKPAPEDYPLFRTVN-IADGKWHRVAISVEKKTVTMIVDCKKKT 186

Query: 203 SLPI--KPRGPIDIDGFAVLGKLADNPQVSVPFELQWMLIHCDP 244
           + P+    R  +D +G  V G    + +V    ++Q  LI  DP
Sbjct: 187 TKPLDRSERAIVDTNGITVFGTRILDEEV-FEGDIQQFLITGDP 229


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  517 bits (1332), Expect = e-146
 Identities = 316/757 (41%), Positives = 363/757 (47%), Gaps = 101/757 (13%)

Query: 244  PLRPRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPG--------------VPGID 289
            P+ P   +    P R      T  RG PGE+GP G  G PG              +PG  
Sbjct: 834  PVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAP 893

Query: 290  GI-------DGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS--------- 333
            G+        G +GP G PGPPGP G PG  G PG  G PG  GLT   GS         
Sbjct: 894  GLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLK 953

Query: 334  -------------PGSIGSKGQKGEPGVPG--------------------------SRGF 354
                         PG +  KG+KG+ G+PG                          S G 
Sbjct: 954  SICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGD 1013

Query: 355  PG----RGIPGPPG---------PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGT 401
            PG     G+PGPPG         PPG  G PG  G +GP G PG  G PG PG  G RG 
Sbjct: 1014 PGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGL 1073

Query: 402  IGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA 461
             G   GD   P   PPG+ GYPG  G  G  G KGE G  G  G KGE G  G  G  G 
Sbjct: 1074 TGL-TGDKGEPG--PPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGP 1130

Query: 462  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 521
             GP G +G RG  G  G+KG++G +G  G PGP G PG PG  G  GPPG    KG  G 
Sbjct: 1131 PGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGI 1190

Query: 522  EGARGIPGLPGP------KGDTGLPGVDGRDGIPGM---PGTKGEPGKPGPPGDAGLQGL 572
             G  G+PG PGP      +G  GL G+DG+DG PG+   PG  G PG  GPPG  G  G 
Sbjct: 1191 RGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGH 1250

Query: 573  PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG--EL 630
            PG+PG  G  G  G  GSTG PG  G+ G  G  G+ GPPG VGP GP G PG  G   +
Sbjct: 1251 PGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAV 1310

Query: 631  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 690
            G  G  G  G+ G  G PG PG PG PG PG  G  G  G+ GP G+QG  G  G  G+ 
Sbjct: 1311 GLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDP 1370

Query: 691  GELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQ 750
            G  G  G  G KG AG PG PG  G  G  G PG  G RG PG  G  G  G  G+PG  
Sbjct: 1371 GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSM 1430

Query: 751  GPP-GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
            G         + I+Q  +++  E  A   + ++ P   A   PGRPGPPG  G PG  G 
Sbjct: 1431 GDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAA-PGRPGPPGKDGAPGRPGA 1489

Query: 810  PGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYG 869
            PG  G+ G  G +G  G  G+RG  G  GEKG+ G    G NGLPG    PG  GP  YG
Sbjct: 1490 PGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGP---PGPQGPPGYG 1546

Query: 870  RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
            + G  G  G  G+ GIPG PGP G PG  G C P+ C
Sbjct: 1547 KMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDC 1583



 Score =  495 bits (1275), Expect = e-140
 Identities = 381/1138 (33%), Positives = 490/1138 (43%), Gaps = 304/1138 (26%)

Query: 53   DLPGFDLISQFQVDKAASRRAIQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYS 112
            ++ GF+LI +  + K ++ + I+   G   L++            PTR ++P GLPEE++
Sbjct: 47   NVTGFNLIHRLSLMKTSAIKKIRNPKGPLILRLGA-----APVTQPTRRVFPRGLPEEFA 101

Query: 113  FLTTFRMTGSTLKKNWNIWQIQDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAAFSNL 172
             + T  +   T +K W ++Q+ D++G  Q+ +++N Q +S+    +G DG   +  F  +
Sbjct: 102  LVLTLLLKKHTHQKTWYLFQVTDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIFP-V 160

Query: 173  SSLFDSQWHKIMIGVERSSATLFVDCNRIESLPIKPRGPIDIDGFAVLGKLADNPQVSVP 232
              LFD +WHK+M+ V    A++ VDC+   S P+ PR P+   G   LG  A+  +  V 
Sbjct: 161  PQLFDLRWHKLMLSVAGRVASVHVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGK-PVS 219

Query: 233  FELQWMLIHCDPLRPRRETCHE-LPA----------RITPSQTTDERGPPGE-------- 273
            F+LQ + I+CDP     E C E LPA          R T S    E  P  E        
Sbjct: 220  FDLQQVHIYCDPELVLEEGCCEILPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCF 279

Query: 274  --QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT---PGADGLT 328
              + P        + G      +RG K           P   GA     T    G  G  
Sbjct: 280  CLEEPQNSEVDAQLTGRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGK 339

Query: 329  GPDGSPGSIGSKGQK--------------------------------GEPGVPGSRGFPG 356
            G  G PG  GSKG+K                                G  G+PGS G  G
Sbjct: 340  GERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKG 399

Query: 357  R-------GIPGPPGPPGTAGLPGELGRVGP---VGDPGRRGP------PGPPGPPGPRG 400
            +       GI G PG PG  G PGE+  +GP    GDPG  GP      PGPPG PGP G
Sbjct: 400  QKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPG 459

Query: 401  TIGFHDGDPLCPNACP-----------PGRSGYPGLPGMRGHKGAKGE------------ 437
             IG   G P  P   P           PG+ G  G PG  G KG KG+            
Sbjct: 460  -IGL-PGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGF 517

Query: 438  ---IGEPGRQGHKGEEGD-------------QGELGE--------VGAQ----------- 462
               +G PG+ G KGE GD             +GE GE        VGAQ           
Sbjct: 518  QNFVGLPGKPGPKGEPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGD 577

Query: 463  ------GPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG-------------------- 496
                  G PG  G  G+ G+ G+KG  G  G  G PGP G                    
Sbjct: 578  VGSPGFGLPGLPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPA 637

Query: 497  -------------LPGAPGDQGQRGPP--------GEAGPKGDRGAEGARGIPGLPGPKG 535
                         LPG  G++G+ GPP        G+AG +G +G +G  G PG PG  G
Sbjct: 638  LSNLQDGDVRVVALPGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPG 697

Query: 536  DTGLPGVDGRDGIPGMPGTKGE---------------------PGKPGPPGDAGLQGL-- 572
             TG PG+ G  G+ G  G KGE                     PG+PGP G+ G +G+  
Sbjct: 698  TTGRPGLSGEPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGR 757

Query: 573  ---PGVPGIPGAKGVAGEKGSTGAPGKPGQ--MGNSGKPGQQGPPGEVGPRGPQGLPGSR 627
               PG PG+PG +G  G KG  G PG PG+   G  G+PG  G PG  G  GP+G PG  
Sbjct: 758  PGKPGQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPT 817

Query: 628  GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEA 687
            GE G  GSPG+ G  G +G PG   + GPPG  G +G  G+ G PG KG +G  GE GE 
Sbjct: 818  GEKGAQGSPGVKGATGPVGPPG-ASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGEC 876

Query: 688  G--ERGELGDIGLPGPKGS-AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT 744
                +G+L   G+PG  G   G+  +P   GP+G  G+PG  GP G PG +GV G  G  
Sbjct: 877  SCPSQGDLIFSGMPGAPGLWMGSSWQP---GPQGPPGIPGPPGPPGVPGLQGVPGNNGLP 933

Query: 745  GLPGVQGPPGRAPTDQH-IKQVCMRVIQ--------------------------EHFAEM 777
            G PG+    G  P +QH +K +C   +Q                          ++ A+ 
Sbjct: 934  GQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQC 993

Query: 778  AASLKRP------------DSGATGLPGRPGP------------------PGPPGPPGEN 807
              SL+RP            D G  G PG PGP                  PGPPGP G  
Sbjct: 994  FLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPP 1053

Query: 808  GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGL------------- 853
            GFPG +G  GLPG++G  G  GL G KG+ G  G+ G PG  GP GL             
Sbjct: 1054 GFPGAVGSPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSA 1113

Query: 854  --------PGAIGLPGDPGPA----SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
                    PG+ GLPG PGPA      G  G  GE+G  G  G PG PGPPGPPG PG
Sbjct: 1114 GEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPG 1171



 Score =  476 bits (1226), Expect = e-134
 Identities = 321/800 (40%), Positives = 358/800 (44%), Gaps = 154/800 (19%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP----------- 303
            LP R        E+G  GE GP G PGPPG  G  GI G +G    P P           
Sbjct: 588  LPGRAGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVR 647

Query: 304  ----PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-- 357
                PGP+GE G+PG PG  G PG  G  G  G  G  G  G  G+PG PG+ G PG   
Sbjct: 648  VVALPGPSGEKGEPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSG 706

Query: 358  --GIPGPPGPPGTAG---------------------LPGELGRVGP--VGDPGRRGPPGP 392
              G+ GP GP G  G                      PG  G  GP  VG PG+ G PG 
Sbjct: 707  EPGVQGPAGPKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGL 766

Query: 393  PGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGD 452
            PG  GP G  G   G+P  P     G  G PG PG+ G +G  G  G PG  G KG +G 
Sbjct: 767  PGVQGPPGLKGVQ-GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGS 825

Query: 453  QGELGEVGAQGPPGAQ--------GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD- 503
             G  G  G  GPPGA         G +G TG+ G  GEKG RG  GEPG    P + GD 
Sbjct: 826  PGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP-SQGDL 884

Query: 504  --QGQRGPPGE-AGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 560
               G  G PG   G     G +G  GIPG PGP G  GL GV G +G+PG PG   E G 
Sbjct: 885  IFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGS 944

Query: 561  ----------------------PG---PPGDAGLQGLPGVPGIP---------------- 579
                                  PG     G+ G QG+PGVPG+                 
Sbjct: 945  LPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEE 1004

Query: 580  -------GAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG---------L 623
                   G  G  G  G  G PG PGQ G  G PG +G PG  GP GP G         L
Sbjct: 1005 ARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGL 1064

Query: 624  PGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG------EPGPKGE 677
            PG +GE G  G  G  G+ G  G PG PG  GPPGLPG+KG+RG  G      EPGP G 
Sbjct: 1065 PGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGS 1124

Query: 678  QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP--- 734
            +G  G  G AG RGE G  G  G KG  G  G+PG  GP G  G PG  G  GPPGP   
Sbjct: 1125 EGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAE 1184

Query: 735  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 794
            +G +G +G +GLPG  GPPG                     +  A L   D G  G PG 
Sbjct: 1185 KGSEGIRGPSGLPGSPGPPGPPGI-----------------QGPAGLDGLD-GKDGKPGL 1226

Query: 795  PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGL 853
             G PGP GPPG  G PG  G  G PG+ GP G  G  GP G  G  G  G PG  GP G 
Sbjct: 1227 RGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGR 1286

Query: 854  PGAIGL------PGDPGPASY------GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 901
            PG  G       PG PGPA        G  G  GERG  G+ G PG PG PGPPG PG  
Sbjct: 1287 PGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTD 1346

Query: 902  EPASCTMQAGQRAFNKGPDP 921
              A      G++ F   P P
Sbjct: 1347 GAAGKEGPPGKQGFYGPPGP 1366



 Score =  372 bits (956), Expect = e-103
 Identities = 244/600 (40%), Positives = 274/600 (45%), Gaps = 141/600 (23%)

Query: 258  RITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA-- 315
            R   ++  +  G PG  G PG PGPPG+PG  G +G  G +G PGPPGP G PG PGA  
Sbjct: 1001 RAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVG 1060

Query: 316  ----------------------PGKPGTPGADGLTGPDGSPGS------IGSKGQKGEPG 347
                                  PG PG PG  G TGP G PG        GS G+KGEPG
Sbjct: 1061 SPGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPG 1120

Query: 348  VPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDG 407
             PGS G PG   PGP GP G  G  G  G  G  G  G+ G PGPPGPPG  G +G    
Sbjct: 1121 PPGSEGLPGP--PGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVG--SP 1176

Query: 408  DPLCPNA--------CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEV 459
             P  P A         P G  G PG PG  G +G  G  G  G+ G  G  GD G  G  
Sbjct: 1177 GPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPP 1236

Query: 460  GAQGPPGAQGLRGITGIVGDKGE---------KGARGLDGEPG---PQGLPGAPGDQGQR 507
            G  GPPG +G  G  G+ G KG+          G  G +GEPG   PQG PG PG  G  
Sbjct: 1237 GLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPP 1296

Query: 508  GPPGEAGP--------KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG 559
            GPPG+ GP        KGDRGA G RG+ GLPG       PG  G  G PG PGT G  G
Sbjct: 1297 GPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQ------PGPPGHPGPPGEPGTDGAAG 1350

Query: 560  KPGPPGDAGLQGLPGVPGIPGA---KGVAGEKGSTGAPGKPGQMGNSGKPGQQGP----- 611
            K GPPG  G  G PG  G PGA   KG AGEKG  G PG PG+ G+ G  G  GP     
Sbjct: 1351 KEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERG 1410

Query: 612  -PGEVGPRGPQGLPGSRGELG--------------------------------------- 631
             PG  GP G  GLPG  G +G                                       
Sbjct: 1411 HPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAA 1470

Query: 632  ------PVGSPGLPGKLGSLGSPGLPG---------LPGPPGLPGMKGDRGVVGE----- 671
                  P G  G PG+ G+ GSPGLPG         LPG  GLPG KG++G +G      
Sbjct: 1471 APGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGE 1530

Query: 672  ---PGPKGEQGASG--EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 726
               PGP G QG  G  + G  G  G+ G  G+PGP G  G PG+ G   P    G   +E
Sbjct: 1531 NGLPGPPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPME 1590



 Score =  183 bits (464), Expect = 7e-46
 Identities = 128/342 (37%), Positives = 153/342 (44%), Gaps = 44/342 (12%)

Query: 584 VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP-------VGSP 636
           V G + S       G  G  G+ G  GPPG  G +G +G    R  + P        G  
Sbjct: 320 VHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVR--ISPDAPLQCAEGPK 377

Query: 637 GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 696
           G  G+ G+LG  GLPG  G  G  G KGD G+ G PG  G  G  GE    G +G+ GD 
Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDP 437

Query: 697 GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG-PRGPPGPRGVQGEQGATGLPGVQGPPGR 755
           G  GP+G AG PG PGL GP G  GLPG  G P GPPGP+G +G  G  G  G  G PG+
Sbjct: 438 GFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGK 496

Query: 756 APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGI 815
                     C         E+  +L        GLPG+PGP G PG P      G  GI
Sbjct: 497 PGVKGEKGDPC---------EVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR--GDPGI 545

Query: 816 RGLPGIKGPP-----GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGR 870
           +G+ G KG P       +G +      G  G+ G PG G  GLPG  G+PG         
Sbjct: 546 QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPG--------- 596

Query: 871 NGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 912
               GE+G  G AG      P G PG PG   PA      G+
Sbjct: 597 --LKGEKGNFGEAG------PAGSPGPPGPVGPAGIKGAKGE 630



 Score =  112 bits (281), Expect = 1e-24
 Identities = 74/213 (34%), Positives = 84/213 (39%), Gaps = 60/213 (28%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPK------------------------------ 298
            GP GE+G PG PGP G PG+ G+ G  G                                
Sbjct: 1404 GPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQ 1463

Query: 299  ---------GPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVP 349
                     G PGPPG  G PG+PGAPG PG PG  G  G  G PG  G  G KGE G  
Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI 1523

Query: 350  GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD---------PGRRGPPGPPGPPGPRG 400
            G       G+PGPPGP G  G  G++G  GP+G          PG  G PG  G   P  
Sbjct: 1524 GIGIAGENGLPGPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSD 1582

Query: 401  TIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKG 433
              G             P    YP +  M+G  G
Sbjct: 1583 CFG-----------AMPMEQQYPPMKTMKGPFG 1604


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  517 bits (1331), Expect = e-146
 Identities = 310/701 (44%), Positives = 360/701 (51%), Gaps = 100/701 (14%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326
            E GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G
Sbjct: 644  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 703

Query: 327  LTGPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPG 373
              GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG
Sbjct: 704  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPG 763

Query: 374  ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMR 429
              G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  
Sbjct: 764  SRGEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGAS 822

Query: 430  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIV 477
            G KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  
Sbjct: 823  GEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQ 882

Query: 478  GDKGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGAR 525
            G  G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G R
Sbjct: 883  GPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGER 942

Query: 526  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAK 582
            G PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG K
Sbjct: 943  GHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002

Query: 583  GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 642
            G  G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ 
Sbjct: 1003 GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 1062

Query: 643  GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
            G  G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   
Sbjct: 1063 GVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP--- 1119

Query: 703  GSAGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPP 753
            G+AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPP
Sbjct: 1120 GAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPP 1179

Query: 754  G----RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 809
            G    R P                            +GA G  G PG  G  GPPGE G 
Sbjct: 1180 GPPGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 810  PGQM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGL 859
            PG+    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G 
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGF 1271

Query: 860  PGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
            PGDPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1272 PGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1312



 Score =  506 bits (1303), Expect = e-143
 Identities = 299/686 (43%), Positives = 343/686 (50%), Gaps = 65/686 (9%)

Query: 261  PSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 320
            P   T + G  G  G  GP GPPG  G+ G  G  G  GP GPPGP G+ G PG PG+ G
Sbjct: 851  PRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG 910

Query: 321  TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 380
              G  G TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G 
Sbjct: 911  EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGT 965

Query: 381  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 440
             GDPG   PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G 
Sbjct: 966  KGDPG---PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGS 1016

Query: 441  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGL 497
            PG +G  G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G 
Sbjct: 1017 PGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGP 1076

Query: 498  PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 557
            PG  G+ G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G 
Sbjct: 1077 PGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGH 1136

Query: 558  PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 617
             G  G  G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G 
Sbjct: 1137 FGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGA 1193

Query: 618  RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGE 677
             GPQG PG  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G 
Sbjct: 1194 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1253

Query: 678  QGASGEEGEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGL 722
            +G +G++G  G  G +G  G PGP               +G  G PG+PG  GP G  G 
Sbjct: 1254 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1313

Query: 723  PGVEGPRGP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFA 775
            PG  G RGP   PG  G QG +GA G PG  G PG+     P     K        +   
Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLR 1368

Query: 776  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKG 835
             +  S+     G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G
Sbjct: 1369 GLPGSV-----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1423

Query: 836  DLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 895
            + GEKG+RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP 
Sbjct: 1424 EQGEKGDRGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPK 1470

Query: 896  GLPGFCEPASCTMQAGQRAFNKGPDP 921
            G  G   P     + G +     P P
Sbjct: 1471 GAKGATGPGGPKGEKGVQGPPGHPGP 1496



 Score =  504 bits (1298), Expect = e-142
 Identities = 308/711 (43%), Positives = 355/711 (49%), Gaps = 78/711 (10%)

Query: 250  ETCHELPARITPSQTTDERGPPGE-------QGPPGPPGPPGVPGIDGIDGDRGPKGPPG 302
            ET H   A   P     E+G P         +GPPGP GP G+ G  GI G+ GP G PG
Sbjct: 367  ETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPG 426

Query: 303  ---PPGPAGEPGKPGAPGKPGT----PGADGLTGPDGSPGSIGSKGQKGE---------P 346
               PPG AG PG  GAPG PGT    P   G  G D  P     + Q             
Sbjct: 427  ERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALR 486

Query: 347  GVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD 406
            G PG  G+ GR  PGP G PG+ GL GE G +GP G  G +G  GPPG  G RG  G   
Sbjct: 487  GPPGPMGYTGR--PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADG 544

Query: 407  -----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE--- 458
                 GDP        G  G PGLPG +GH+G  G  G PG  G  GE GD GE+G    
Sbjct: 545  ARGMPGDPGVKG--DRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 602

Query: 459  ---------VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP 509
                     +G +GPPG  G  G+ G+ G +G KG+ G  GEPGP G  G PG QG  GP
Sbjct: 603  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662

Query: 510  PGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL 569
             G  GP G++G +G  G+PG+PG  G    PG  G++G PG  G +G  G  GP G  G 
Sbjct: 663  QGAIGPHGEKGPQGKPGLPGMPGSDGP---PGHPGKEGPPGTKGNQGPSGPQGPLGYPGP 719

Query: 570  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 629
            +G+ GV GI G KG  GEKG  G PG  G +G  G  G+ G PG  G  GP+   G +G 
Sbjct: 720  RGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE---GPKGR 776

Query: 630  LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE 689
             GP G PG PG +G  G  G+PGLPG PG  G KG  G  G PG  GE+GA G  G++G 
Sbjct: 777  TGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 836

Query: 690  RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 749
            RGE       GP G  G  G  G  G  G++G  G +GP GPPG RG+ G QG  G PG 
Sbjct: 837  RGE------RGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP 890

Query: 750  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD-------SGATGLPGRPGPPGPPG 802
            +GPPG    D        R  +  F         P        +G TG  G  G PGPPG
Sbjct: 891  KGPPGPPGKDGLPGHPGQRG-EVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPG 949

Query: 803  PPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG----------RGPNG 852
            PPGE G PG  G  G  G  GPPGA G  GP G  G  GERG PG           GP+G
Sbjct: 950  PPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 1009

Query: 853  LPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             PG  G PG+ G A      G  GR G +GPPG AG  GVPG  GP G  G
Sbjct: 1010 PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG 1060



 Score =  486 bits (1251), Expect = e-137
 Identities = 290/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 323
            +RG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 908  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 967

Query: 324  ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 379
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 968  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 434
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085

Query: 435  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 494
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1145

Query: 495  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 554
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205

Query: 555  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1265

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 671
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1266 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325

Query: 672  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 728
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1385

Query: 729  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 776
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1386 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1428

Query: 777  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 831
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1429 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1476

Query: 832  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 889
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1477 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1534

Query: 890  GPPG 893
            G PG
Sbjct: 1535 GSPG 1538



 Score =  476 bits (1226), Expect = e-134
 Identities = 353/983 (35%), Positives = 434/983 (44%), Gaps = 182/983 (18%)

Query: 74  IQRVVGSATLQVAYKLGNNVDFRIPTRNLYPSGLPEEYSFLTTFRMTGSTLKKNWNIWQI 133
           ++R  G     VAY++        PTR L+P G P+++S LT  R           ++  
Sbjct: 47  VRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAPLLTLYSA 106

Query: 134 QDSSGKEQVGIKINGQTQSVVFSYKGLDGSLQTAA---FSNLSSLFDSQWHKIMIGVERS 190
           Q   G  Q+G+++    + V F Y+   G  Q  +   F  LS L D +WH++ + V+  
Sbjct: 107 Q---GVRQLGLELG---RPVRFLYEDQTGRPQPPSQPVFRGLS-LADGKWHRVAVAVKGQ 159

Query: 191 SATLFVDCNR--IESLPIKPRGPIDIDGFAVLG--------------KLADNPQVSVPFE 234
           S TL VDC +     LP   R  +D  G  + G              +LA  P V   +E
Sbjct: 160 SVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYE 219

Query: 235 -LQWMLIHCDP---LRPRRETCH-------ELPARITPSQTTDERGPPGEQ-----GPP- 277
             +   + C+     RP+ +  H       + P+R+   Q  + +  P E       PP 
Sbjct: 220 SCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPY 279

Query: 278 --------------GPPG-----------PP---------GVPGIDGIDGDRGPKGPPGP 303
                           PG           PP           P  D    +   +G   P
Sbjct: 280 YDVMTTGTTPDYQDPTPGEEEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDP 339

Query: 304 P-GPAGEPGKPGAPGKPGT---PGADGLTGPDGSP--GSIGSKGQKGEPGVPGSRGFPGR 357
           P GP       G   +  T   P     T   G+   G  G KG+KGEP V      PG 
Sbjct: 340 PEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLE----PGM 395

Query: 358 GIPGPPGPPGTAGL---PGELGRVGPVGDPGRRGPPG---------PPGPPGPR------ 399
            + GPPGP G AGL   PG  G  GPVGDPG RGPPG          PGPPG        
Sbjct: 396 LVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFR 455

Query: 400 -GTIGFHDGDPLCPNAC---------------PPGRSGYPGLPGMRGHKGA---KGEIGE 440
            G+ G   G  +                    PPG  GY G PG  G  G+   KGE G+
Sbjct: 456 FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGD 515

Query: 441 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP------ 494
            G QG +G +G  G  G+ G +G  GA G RG+ G  G KG++G  GL G PG       
Sbjct: 516 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGD 575

Query: 495 ---QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGM 551
              QGLPG PG+ G+RG  GE GP+G  G  G RG+ G  GP G  G PGV G DG  G 
Sbjct: 576 TGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGP 635

Query: 552 PGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG---Q 608
            G+ G  G+PGPPG  G  G  G+PG  GA G  GEKG  G PG PG  G+ G PG   +
Sbjct: 636 KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGK 695

Query: 609 QGPPGEVG------PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 662
           +GPPG  G      P+GP G PG RG  G  G  GL G  G  G  G PG  G  G+   
Sbjct: 696 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV--- 752

Query: 663 KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL---RGPEGS 719
           KGDRG VG PG +GE G  G +G  G  G+ G  GL G KG  G PG PG    +GP+GS
Sbjct: 753 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGS 812

Query: 720 RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-RAPTDQHIKQVCMRVIQEHFAEMA 778
            G PG  G  G  G RG+ G+ G  G  G  GP G R P                     
Sbjct: 813 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGP--------------------- 851

Query: 779 ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 838
               R  +G +G  G  G  GP GPPGE G PG  G  G PG KGPPG  G  G  G  G
Sbjct: 852 ----RGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPG 907

Query: 839 EKGERGPPGR-GPNGLPGAIGLPGDPGPAS-YGRNGRDGERGPPGVAGIPGVPGP----- 891
           ++GE G  G+ GP G PG +G  G  G     G  G  G  GPPG  G+PG  G      
Sbjct: 908 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 967

Query: 892 -PGPPGLPGFCEPASCTMQAGQR 913
            PGPPG PG   PA      G+R
Sbjct: 968 DPGPPGAPGKDGPAGLRGFPGER 990



 Score =  424 bits (1089), Expect = e-118
 Identities = 255/595 (42%), Positives = 296/595 (49%), Gaps = 62/595 (10%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAG 308
            LP       T  + GPPG  G  GP      PG  G+PG  G  G +G +GP GPPGPAG
Sbjct: 956  LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015

Query: 309  EPGK------------PGAPGKPGTPGAD------------------------GLTGPDG 332
             PG+            PG PG  G PGA                         GL GP G
Sbjct: 1016 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 1075

Query: 333  SPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPG 391
             PG  G  G KGE G PG +G  G +G  GPPGPPG  G  G+ G  G  G+PG RGP G
Sbjct: 1076 PPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG 1135

Query: 392  PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 451
              G  G  GT GF+          PPG  G  GLPG  G KG  G++G  G  G  G  G
Sbjct: 1136 HFGAKGDEGTRGFNG---------PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG 1186

Query: 452  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---GPQGLPGAPGDQGQRG 508
              G  G  G QGPPG  G  G  G  G+ GE G+ G+ GEP   GP+G  G  G+ GQ G
Sbjct: 1187 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPG 1246

Query: 509  PPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
             PG  GPKG  G +G +G PG  G  GD G PG  G  G  G  G +GE G+PG PG  G
Sbjct: 1247 EPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPG 1306

Query: 569  LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
              G  G PG  G +G AG  GS G  G  G  G+ G  G  G  G VGP GP G PG  G
Sbjct: 1307 PTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDG 1366

Query: 629  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 688
              G  GS G  G+ G+ G  G PG  GPPGLPG++GD G  GE   KG  G  G  G  G
Sbjct: 1367 LRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPG 1423

Query: 689  ERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 745
            E+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP GP G +G  G  G  G
Sbjct: 1424 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG 1483

Query: 746  LPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
              GVQGPPG   P  + I+ + +++ ++    +  S    +  A    G PG PG
Sbjct: 1484 EKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPG 1538


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 269  GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 319
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 320  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 379
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 440  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 482
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 483  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 522
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 523  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 573
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 574  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 627
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 628  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 679
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 680  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 715
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 716  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 770
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 771  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 820
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 821  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 867
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 868  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  490 bits (1261), Expect = e-138
 Identities = 327/815 (40%), Positives = 382/815 (46%), Gaps = 197/815 (24%)

Query: 253  HELPARITPSQTTDERGPPGEQGP--------PGPPGPPGVPGIDGIDGDRGPKGP---- 300
            H LP  +         GP GE G         PGPPG PG+PG+ G+ G  G +G     
Sbjct: 451  HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLK 510

Query: 301  --------------PGPPGPAGEP----------------GKPGAPGK------------ 318
                          PG PG  G+P                G PG PG             
Sbjct: 511  GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 319  PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG---------------------R 357
            PGTPG  GL GP G     G KG +G PG PGS G PG                     +
Sbjct: 571  PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630

Query: 358  GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF------------- 404
            G+PG PGPPG AG  GEL    PV  PG  GPPGPPG PGP+G  G              
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPV--PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688

Query: 405  -HDGDPLCPN---ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE--LGE 458
              DG+P  P      PPG  G  G PG +G  G  G++GEPG  G  G  G +GE  +  
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
             G  G PG  G RG +G  G+ G  G  GL G PG +GL G  GD GQ GPPGE GP G 
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR 808

Query: 519  --RGAEGARGIPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 564
               G  GA+G+PGL             GPKGD G+PG+D R G PG  G+ G PG  G  
Sbjct: 809  CIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD-RSGFPGETGSPGIPGHQGEM 867

Query: 565  GDAGLQGLPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ 621
            G  G +G PG PGI   PG  GV G  G  GA G PG  GN G PGQ+G PG  G +G +
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 622  GLPGSRGE---------------LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 666
            G PG++GE               +G  G PGL G  G+ G  G  G+PG PGL G+KG  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 667  GVVGEPGPKGEQGASGEEGEAGER---GELGDIGLPGPKGS---------AGNPGEPGLR 714
            G  G PGP+G+ G++G  GE G R   G +G++G+PG KG          AG PG PG+ 
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 715  GPEGSRGLPGVE-----GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
            G +G +G PG       GP GP G  G+ G+ G  G  G  GPPG               
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPG--------------- 1092

Query: 770  IQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP----- 824
               H             GA G PG PG PG PGP G+ GF G  G+ G PGI+GP     
Sbjct: 1093 ---HLGPAG------PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 825  ----PGALGLRGPK------GDLGEKGE----RGPPGRGPNGLPGAIGLPGDPG----PA 866
                PG +G+RG +      G  GEKGE    R PP  GP G PGA G  GD G    P 
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPG 1201

Query: 867  SYGRNGRDGERGPPGVAGIPGVPGPPGPPG--LPG 899
              GR G  G+ GP G  GI G PGPPG PG  +PG
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236



 Score =  489 bits (1259), Expect = e-138
 Identities = 304/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 324
            ERG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 325  DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 384
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 385  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 443
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 444  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 504  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 552
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 553  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 600
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 601  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 656
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 657  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 702  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 757
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 758  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 818  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 877  RGPPGVAGIPGVPGPPGPPGLPGFCEP 903
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1247), Expect = e-136
 Identities = 319/753 (42%), Positives = 372/753 (49%), Gaps = 112/753 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGI------------------DGIDGDRGP 297
            P+ +       E+G PG+ G  G PG  GVPG                   DGI G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 298  KGPPGPPGPA---------GEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSK--GQKGEP 346
             GPPG  GP          G+ G PG PG  G  G  G +GP G PGS GS   G +G P
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 347  GVP------GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPG----RRGPPGPPGPP 396
            G P      G RG PG+   G PG PG AG PG  G  GP G PG    R+GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 397  GPRGTIGF-----HDGDP-LCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 448
            G  G+ G        G+P L    CP  PG  G PGLPG+ G KG  G  G  G +G  G
Sbjct: 455  GYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG 514

Query: 449  EEGD---QGELGEVGAQGPPGAQGLRGIT----GIVGDKGEKGARGLDGEPGPQGLPGAP 501
              G+    G  G  GAQG PG +G +G T    G VG  G+ G RG  G  G  G+PG P
Sbjct: 515  SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 502  GDQGQRGPPGE---AGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G +G  GP GE   +G KGD+G  G  G PG PGP G  G PG  G  G PG+ GT+G P
Sbjct: 575  GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVP 633

Query: 559  GKPGPPGDAGLQG----LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
            G PGPPG+AG +G       VPG PG  G  G  G  G PG PG +G  G PG  GP GE
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP 674
             G  G  G PG  G  G  G PG  G LG  G  G PGLPG PGLPG KG+   V  PG 
Sbjct: 694  PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE-PAVAMPGG 751

Query: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP------GEPGLRGPEGSRGLPG--VE 726
             G  G  GE G +GE GE+G  GLPG  G+ GN       G+PG  GP G +G PG  +E
Sbjct: 752  PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIE 811

Query: 727  GPRGP---PGPRGVQGEQGATGLPGVQGPPGRAPTDQ--HIKQVCMRVIQEHFAEMAASL 781
            GPRG    PG  G++G+QG  G  G +G PG    D+     +     I  H  EM    
Sbjct: 812  GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 782  KR------------PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 829
            +R             + G  G+ G PG  GPPGPPG  G PGQ G  G+PG+KG  G  G
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 830  LRGPKGD------------LGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS 867
             +G +GD            +G+KGE G  G          RG  G+PG  GL G PGPA 
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAG 991

Query: 868  -YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  G  G PG  G+ G+PG  G  G+PG
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024



 Score =  477 bits (1228), Expect = e-134
 Identities = 304/726 (41%), Positives = 367/726 (50%), Gaps = 124/726 (17%)

Query: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGAPG 317
           E+G  G  GPPG PG  G  G +G+ G +GPKG PG PG  G          PG  G+PG
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPG 106

Query: 318 KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG--------------------- 356
            PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG                     
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166

Query: 357 ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413
              +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G H G+ +   
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG-HMGERVI-- 223

Query: 414 ACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 468
               G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE    GPPG  
Sbjct: 224 ----GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE---PGPPGPS 276

Query: 469 GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGPKGDRGAEGAR 525
           GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G  G +G +G  
Sbjct: 277 GLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI 335

Query: 526 GIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA--GLQGLPG 574
           G PG  GP         KGD G PG  G  G  G  G  G PG PG PG +  GL+G PG
Sbjct: 336 GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 575 VPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----RGPQGLPGSRG 628
            PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +GP   PG  G
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHG 452

Query: 629 ELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE 683
             G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P   G QGA+G 
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP---GRQGAAGL 509

Query: 684 EGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPRGPPGPRGVQG 739
           +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G RG PG +G+ G
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
             G  G+ G+ GP G                     E+A S ++ D G  G PG PG PG
Sbjct: 570 IPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPPGDPGSPGSPG 608

Query: 800 PPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEKGERGPPG--- 847
           P GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  G  GPPG   
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 848 -RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
            +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G PG      C
Sbjct: 669 PQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGC 722

Query: 907 TMQAGQ 912
             + G+
Sbjct: 723 PGKMGE 728



 Score =  467 bits (1202), Expect = e-131
 Identities = 312/773 (40%), Positives = 371/773 (47%), Gaps = 150/773 (19%)

Query: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGV---PGIDGIDGDRGPKGPP----------- 301
           P    P       G  G +G  G PG PG    PGI G  G +G KG P           
Sbjct: 111 PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAK 170

Query: 302 GPPGPAGEPGKPGAPGKPGTPGADGLTGPD---GSPGSIGSKGQKGEPG--VPGSRGFPG 356
           G PG  G PG  G PG PG PG  G  GP    G PG++G +G KG  G  V G +G  G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 357 -RGIPGPPGPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPP 393
            +G+ GPPGPPGT             L GE G  G +G+PG  GP            G P
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 394 GPPGPRGTIGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG------- 445
           G PG +G  G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G       
Sbjct: 291 GDPGLQGKPG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 446 --HKGEEGDQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-- 484
              KG+EG  G  G  GA+GP                 PG +G  G  G+ G KGE+G  
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 485 ---ARGLDGEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPK 534
              A G  G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPK
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469

Query: 535 GDTGL--------PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPG 577
           G+ GL        PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG
Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529

Query: 578 IPGAKGVAGEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLP 624
             G  G+ GEKG T       G PG PG  G  G+ G  G PG        GP+G   L 
Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589

Query: 625 GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE- 683
           G +G+ GP G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE 
Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648

Query: 684 ---------EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPP 732
                     G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP 
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 733 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792
           G +G  G +G+ G PG  G PG                      +  +   P   A  +P
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMP 749

Query: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRG 849
           G PG PG PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR 
Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 850 PNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 899
             G  GA GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  445 bits (1144), Expect = e-124
 Identities = 279/670 (41%), Positives = 327/670 (48%), Gaps = 131/670 (19%)

Query: 261  PSQTTDERGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---- 305
            P     + GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 306  -------------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEP 346
                               P G+ G PG PG  G PG DG+ G  G PG+IG  G  G P
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 347  GVPGSRGFPG-------------------RGIPGP------------PGPPGTAGLPGEL 375
            G PG RG PG                   +G PGP            PG  G AG PGE 
Sbjct: 910  GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 376  GRVGPVGDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGH 431
            G  G  G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G 
Sbjct: 970  GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGAR 486
            +G  G  G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 487  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
            G  G  GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148

Query: 547  GIPGMPGTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
            G  G+ G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G 
Sbjct: 1149 GPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA 1208

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-- 658
             G  G +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  
Sbjct: 1209 MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSH 1262

Query: 659  LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 718
            + G+KGD+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G
Sbjct: 1263 VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322

Query: 719  SRGL------PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
            + G       PG  GP+GPPG RG  G      LPG  GPPG                  
Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------- 1365

Query: 773  HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
                               PG PG  G PGPPG  G  G  G RG PG  G PG  G  G
Sbjct: 1366 -------------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 833  PKGDLGEKGE 842
             KG+ G KGE
Sbjct: 1407 EKGNKGSKGE 1416



 Score =  337 bits (863), Expect = 4e-92
 Identities = 221/530 (41%), Positives = 258/530 (48%), Gaps = 69/530 (13%)

Query: 433 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 492
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 493 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 553 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 605 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 657
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 658 GLP--------GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
           GLP        G  GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 710 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 759
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 760 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGFPGQ 812
             +K       +     M        +G+ GLPG PGPPGPP       GPPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 813 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 855 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 899
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  327 bits (838), Expect = 3e-89
 Identities = 186/404 (46%), Positives = 216/404 (53%), Gaps = 35/404 (8%)

Query: 268  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKG-----PPGPPGPAGEPGKPGAPGK---- 318
            +G  G  G PG  G PG+PGI G+ GD+G  G      PGPPGP G+PG PG  GK    
Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085

Query: 319  --PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPG---PPGTAGLP 372
              PG PG  G  GP+G+PGS GS G  G+PG  G  GF G +G+ GPPG   PPG  G P
Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145

Query: 373  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK 432
            G  G +G  GD GR G PGP G  G  G +             PPG  G PG  G +G +
Sbjct: 1146 GSPGPMGIRGDQGRDGIPGPAGEKGETGLL-----------RAPPGPRGNPGAQGAKGDR 1194

Query: 433  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 492
            GA G  G PGR+G  G+ G +G  G  G  GPPG  G   I G  G++G  G+RG  G P
Sbjct: 1195 GAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPPGSRGSPGAP 1253

Query: 493  GPQGLPGAP--GDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPG 550
            GP G PG+   G +G +G  G  GPKG  G  G  G PG  G  G  GLPG  G  G  G
Sbjct: 1254 GPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313

Query: 551  MPGTKGEPGKP------GPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604
             PG KGE G P      GPPG  G +G PGV G PG   +    GS G PG PG+ G  G
Sbjct: 1314 FPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQG 1373

Query: 605  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 648
            +PG  GPPG +GP GP+G PG  G+ G  G  G  G  GS G P
Sbjct: 1374 EPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEP 1417



 Score =  270 bits (690), Expect = 5e-72
 Identities = 163/380 (42%), Positives = 191/380 (50%), Gaps = 63/380 (16%)

Query: 267  ERGPPG-----EQGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGKPGAPGK 318
            ++G PG       GPPGP G PG+PG  G  G+ G  GPPG   P GP G PG PG+PG 
Sbjct: 1052 DKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGL 1111

Query: 319  PGTPGADG---------------------LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG- 356
            PG PG  G                     L G  GSPG +G +G +G  G+PG  G  G 
Sbjct: 1112 PGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGE 1171

Query: 357  ----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP 412
                R  PGP G PG  G  G+ G  G  G PGR+G  G  GP GP G  GF  G P  P
Sbjct: 1172 TGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLP 1230

Query: 413  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 472
             A  PG++G  G PG RG  GA G  G PG     G +GD+G +G  G +GPPG  G  G
Sbjct: 1231 GAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI-GIKGDKGSMGHPGPKGPPGTAGDMG 1289

Query: 473  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRG------PPGEAGPKGDRGAEGARG 526
              G +G  G  G  G  G+PG QG PG  G++G  G      PPG  GPKG  G  G  G
Sbjct: 1290 PPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349

Query: 527  ------IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD---AGLQGLPGVPG 577
                  +PG PGP             G PG PG +GEPG PGPPG+    G +G PG  G
Sbjct: 1350 TLKIISLPGSPGP------------PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 578  IPGAKGVAGEKGSTGAPGKP 597
             PG  G AGEKG+ G+ G+P
Sbjct: 1398 KPGTPGPAGEKGNKGSKGEP 1417



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 513 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 569 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 680
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 681 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 734
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 735 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 785 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 833
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 834 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 881
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 882 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 2e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 643 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 703 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 762
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 763 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 817
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 818 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 851
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 852 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 893
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 894 PPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  179 bits (455), Expect = 8e-45
 Identities = 102/202 (50%), Positives = 110/202 (54%), Gaps = 16/202 (7%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGK 312
            LP  I P QT + RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G 
Sbjct: 1229 LPGAIIPGQTGN-RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287

Query: 313  PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP-GPPGPPGTAGL 371
             G PG+ G PG  GL GP G PG  G  G KGE G PG  G  G   P GP GPPG  G 
Sbjct: 1288 MGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGD 1347

Query: 372  PGEL------GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
            PG L      G  GP G PG  G  G PGPPGP G +G     P  P    PG+ G PG 
Sbjct: 1348 PGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLG-----PCGPRG-KPGKDGKPGT 1401

Query: 426  PGMRGHKGAKGEIGEPGRQGHK 447
            PG  G KG KG  GEP    H+
Sbjct: 1402 PGPAGEKGNKGSKGEPESLFHQ 1423


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 269  GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 319
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 320  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 379
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 440  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 482
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 483  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 522
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 523  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 573
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 574  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 627
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 628  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 679
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 680  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 715
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 716  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 770
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 771  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 820
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 821  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 867
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 868  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  498 bits (1283), Expect = e-141
 Identities = 327/815 (40%), Positives = 378/815 (46%), Gaps = 207/815 (25%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP-----------PGPPGPAGEPGKPGAPG 317
            GPPG  G PGP GPPG+PG  G  GD G  GP           PGPPGP G+ G PG  G
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 318  KPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPGR----------GIPGPPGP 365
              G PG  G  G  G PG  G+KG+     PG PG+ GFPG           G+PG PG 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG-----PRGTIGFHDGDPLCPNACPPGRS 420
            PGT   PG  G  GP GDPG+ GPPG  GPPG     PRG  G    + L       G++
Sbjct: 779  PGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKT 835

Query: 421  GYPGLPGMRG--HKGAKGEIGEPGRQGHKGEEGDQGELG---EVGAQGPPGAQGLRGITG 475
            G  G PG+ G    G  GE G PG  GH+GE G  G+ G     G  GPPG  G+ G+ G
Sbjct: 836  GPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG 895

Query: 476  IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR------GIPG 529
              G  G  G  G  G PG +G PG PG +GQRG PG  G +GD+G  G        G  G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 530  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGP---------------PGDAGLQGLPG 574
             PG KG  G PG  G  G+PGMPG KG  G PGP               PG+ GL+G+PG
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 575  V------------------------PGIPGAKGVAGEKGS--------------TGAPGK 596
                                     PG+PG  G+ G+KG               TG PG 
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 597  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG---------- 646
            PG MG  G+ GQ GPPG +GP GP+G PGS G  G  G PG  G LG  G          
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGI 1135

Query: 647  --SPGLPGLPGPPGLPGMKGDRGVVGEPGP-------------------------KGEQG 679
               PGLPG PG PG  G++GD+G  G PGP                         KG++G
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 680  ASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPGVEGP 728
            A G  G  G +G +GD G  GP G  G PG PGL           RGP GSRG PG  GP
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGP 1255

Query: 729  RGPPGPR--GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 786
             GPPG    G++G++G+ G PG +GPPG A                        +  P  
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTA----------------------GDMGPP-- 1291

Query: 787  GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGE---- 839
            G  G PG PG PGP G PG  GFPG  G +G PG  G   PPG +G +GP G  G+    
Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351

Query: 840  --------------------KGERGPPGR-------GPNGLPGAIGLPGDPGPASYGRNG 872
                                +GE GPPG        GP G PG  G PG PGPA  G  G
Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKG 1409

Query: 873  RDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 907
              G +G PG AG  G+PG  G  G  G   PA+ T
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG--SPATWT 1442



 Score =  490 bits (1261), Expect = e-138
 Identities = 327/815 (40%), Positives = 382/815 (46%), Gaps = 197/815 (24%)

Query: 253  HELPARITPSQTTDERGPPGEQGP--------PGPPGPPGVPGIDGIDGDRGPKGP---- 300
            H LP  +         GP GE G         PGPPG PG+PG+ G+ G  G +G     
Sbjct: 451  HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLK 510

Query: 301  --------------PGPPGPAGEP----------------GKPGAPGK------------ 318
                          PG PG  G+P                G PG PG             
Sbjct: 511  GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 319  PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG---------------------R 357
            PGTPG  GL GP G     G KG +G PG PGS G PG                     +
Sbjct: 571  PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630

Query: 358  GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF------------- 404
            G+PG PGPPG AG  GEL    PV  PG  GPPGPPG PGP+G  G              
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPV--PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688

Query: 405  -HDGDPLCPN---ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE--LGE 458
              DG+P  P      PPG  G  G PG +G  G  G++GEPG  G  G  G +GE  +  
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
             G  G PG  G RG +G  G+ G  G  GL G PG +GL G  GD GQ GPPGE GP G 
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR 808

Query: 519  --RGAEGARGIPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 564
               G  GA+G+PGL             GPKGD G+PG+D R G PG  G+ G PG  G  
Sbjct: 809  CIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD-RSGFPGETGSPGIPGHQGEM 867

Query: 565  GDAGLQGLPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ 621
            G  G +G PG PGI   PG  GV G  G  GA G PG  GN G PGQ+G PG  G +G +
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 622  GLPGSRGE---------------LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 666
            G PG++GE               +G  G PGL G  G+ G  G  G+PG PGL G+KG  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 667  GVVGEPGPKGEQGASGEEGEAGER---GELGDIGLPGPKGS---------AGNPGEPGLR 714
            G  G PGP+G+ G++G  GE G R   G +G++G+PG KG          AG PG PG+ 
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 715  GPEGSRGLPGVE-----GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
            G +G +G PG       GP GP G  G+ G+ G  G  G  GPPG               
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPG--------------- 1092

Query: 770  IQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP----- 824
               H             GA G PG PG PG PGP G+ GF G  G+ G PGI+GP     
Sbjct: 1093 ---HLGPAG------PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 825  ----PGALGLRGPK------GDLGEKGE----RGPPGRGPNGLPGAIGLPGDPG----PA 866
                PG +G+RG +      G  GEKGE    R PP  GP G PGA G  GD G    P 
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPG 1201

Query: 867  SYGRNGRDGERGPPGVAGIPGVPGPPGPPG--LPG 899
              GR G  G+ GP G  GI G PGPPG PG  +PG
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236



 Score =  489 bits (1259), Expect = e-138
 Identities = 304/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 324
            ERG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 325  DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 384
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 385  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 443
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 444  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 504  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 552
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 553  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 600
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 601  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 656
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 657  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 702  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 757
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 758  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 818  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 877  RGPPGVAGIPGVPGPPGPPGLPGFCEP 903
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1247), Expect = e-136
 Identities = 319/753 (42%), Positives = 372/753 (49%), Gaps = 112/753 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGI------------------DGIDGDRGP 297
            P+ +       E+G PG+ G  G PG  GVPG                   DGI G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 298  KGPPGPPGPA---------GEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSK--GQKGEP 346
             GPPG  GP          G+ G PG PG  G  G  G +GP G PGS GS   G +G P
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 347  GVP------GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPG----RRGPPGPPGPP 396
            G P      G RG PG+   G PG PG AG PG  G  GP G PG    R+GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 397  GPRGTIGF-----HDGDP-LCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 448
            G  G+ G        G+P L    CP  PG  G PGLPG+ G KG  G  G  G +G  G
Sbjct: 455  GYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG 514

Query: 449  EEGD---QGELGEVGAQGPPGAQGLRGIT----GIVGDKGEKGARGLDGEPGPQGLPGAP 501
              G+    G  G  GAQG PG +G +G T    G VG  G+ G RG  G  G  G+PG P
Sbjct: 515  SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 502  GDQGQRGPPGE---AGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G +G  GP GE   +G KGD+G  G  G PG PGP G  G PG  G  G PG+ GT+G P
Sbjct: 575  GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVP 633

Query: 559  GKPGPPGDAGLQG----LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
            G PGPPG+AG +G       VPG PG  G  G  G  G PG PG +G  G PG  GP GE
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP 674
             G  G  G PG  G  G  G PG  G LG  G  G PGLPG PGLPG KG+   V  PG 
Sbjct: 694  PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE-PAVAMPGG 751

Query: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP------GEPGLRGPEGSRGLPG--VE 726
             G  G  GE G +GE GE+G  GLPG  G+ GN       G+PG  GP G +G PG  +E
Sbjct: 752  PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIE 811

Query: 727  GPRGP---PGPRGVQGEQGATGLPGVQGPPGRAPTDQ--HIKQVCMRVIQEHFAEMAASL 781
            GPRG    PG  G++G+QG  G  G +G PG    D+     +     I  H  EM    
Sbjct: 812  GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 782  KR------------PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 829
            +R             + G  G+ G PG  GPPGPPG  G PGQ G  G+PG+KG  G  G
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 830  LRGPKGD------------LGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS 867
             +G +GD            +G+KGE G  G          RG  G+PG  GL G PGPA 
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAG 991

Query: 868  -YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  G  G PG  G+ G+PG  G  G+PG
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024



 Score =  477 bits (1228), Expect = e-134
 Identities = 304/726 (41%), Positives = 367/726 (50%), Gaps = 124/726 (17%)

Query: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGAPG 317
           E+G  G  GPPG PG  G  G +G+ G +GPKG PG PG  G          PG  G+PG
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPG 106

Query: 318 KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG--------------------- 356
            PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG                     
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166

Query: 357 ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413
              +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G H G+ +   
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG-HMGERVI-- 223

Query: 414 ACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 468
               G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE    GPPG  
Sbjct: 224 ----GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE---PGPPGPS 276

Query: 469 GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGPKGDRGAEGAR 525
           GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G  G +G +G  
Sbjct: 277 GLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI 335

Query: 526 GIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA--GLQGLPG 574
           G PG  GP         KGD G PG  G  G  G  G  G PG PG PG +  GL+G PG
Sbjct: 336 GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 575 VPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----RGPQGLPGSRG 628
            PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +GP   PG  G
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHG 452

Query: 629 ELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE 683
             G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P   G QGA+G 
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP---GRQGAAGL 509

Query: 684 EGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPRGPPGPRGVQG 739
           +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G RG PG +G+ G
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
             G  G+ G+ GP G                     E+A S ++ D G  G PG PG PG
Sbjct: 570 IPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPPGDPGSPGSPG 608

Query: 800 PPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEKGERGPPG--- 847
           P GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  G  GPPG   
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 848 -RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
            +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G PG      C
Sbjct: 669 PQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGC 722

Query: 907 TMQAGQ 912
             + G+
Sbjct: 723 PGKMGE 728



 Score =  467 bits (1202), Expect = e-131
 Identities = 312/773 (40%), Positives = 371/773 (47%), Gaps = 150/773 (19%)

Query: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGV---PGIDGIDGDRGPKGPP----------- 301
           P    P       G  G +G  G PG PG    PGI G  G +G KG P           
Sbjct: 111 PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAK 170

Query: 302 GPPGPAGEPGKPGAPGKPGTPGADGLTGPD---GSPGSIGSKGQKGEPG--VPGSRGFPG 356
           G PG  G PG  G PG PG PG  G  GP    G PG++G +G KG  G  V G +G  G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 357 -RGIPGPPGPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPP 393
            +G+ GPPGPPGT             L GE G  G +G+PG  GP            G P
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 394 GPPGPRGTIGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG------- 445
           G PG +G  G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G       
Sbjct: 291 GDPGLQGKPG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 446 --HKGEEGDQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-- 484
              KG+EG  G  G  GA+GP                 PG +G  G  G+ G KGE+G  
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 485 ---ARGLDGEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPK 534
              A G  G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPK
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469

Query: 535 GDTGL--------PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPG 577
           G+ GL        PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG
Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529

Query: 578 IPGAKGVAGEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLP 624
             G  G+ GEKG T       G PG PG  G  G+ G  G PG        GP+G   L 
Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589

Query: 625 GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE- 683
           G +G+ GP G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE 
Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648

Query: 684 ---------EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPP 732
                     G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP 
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 733 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792
           G +G  G +G+ G PG  G PG                      +  +   P   A  +P
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMP 749

Query: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRG 849
           G PG PG PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR 
Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 850 PNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 899
             G  GA GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  462 bits (1190), Expect = e-130
 Identities = 293/701 (41%), Positives = 344/701 (49%), Gaps = 134/701 (19%)

Query: 261  PSQTTDERGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---- 305
            P     + GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 306  -------------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEP 346
                               P G+ G PG PG  G PG DG+ G  G PG+IG  G  G P
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 347  GVPGSRGFPG-------------------RGIPGP------------PGPPGTAGLPGEL 375
            G PG RG PG                   +G PGP            PG  G AG PGE 
Sbjct: 910  GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 376  GRVGPVGDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGH 431
            G  G  G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G 
Sbjct: 970  GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGAR 486
            +G  G  G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 487  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
            G  G  GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148

Query: 547  GIPGMPGTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
            G  G+ G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G 
Sbjct: 1149 GPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA 1208

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-- 658
             G  G +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  
Sbjct: 1209 MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSH 1262

Query: 659  LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 718
            + G+KGD+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G
Sbjct: 1263 VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322

Query: 719  SRGL------PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
            + G       PG  GP+GPPG RG  G      LPG  GPPG                  
Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------- 1365

Query: 773  HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
                               PG PG  G PGPPG  G  G  G RG PG  G PG  G  G
Sbjct: 1366 -------------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 833  PKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASYGRNG 872
             KG+ G KGE GP   G +GLPG  G  GD G PA++   G
Sbjct: 1407 EKGNKGSKGEPGP--AGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  337 bits (865), Expect = 2e-92
 Identities = 202/486 (41%), Positives = 237/486 (48%), Gaps = 87/486 (17%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            G PGE+G  G PG PG+ G+ G+ G  GP GP G  G  G PG+PG  G PG+ G  G+ 
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 329  GPDGSPGSIGSKGQKGEPGVPGSRGFPG--------RGI-PGPPGPPGTAGLPGELGR-- 377
            G  G  G++G  G+ G PG+PG  G  G         G  PGPPGP G  GLPG++G+  
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 378  -------------VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGR 419
                          GP G PG  G PG PG PGP G +GF       G P      PPG 
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--PPGL 1141

Query: 420  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGE----------EGDQGELGEVGAQGPPGAQG 469
             G+PG PG  G +G +G  G PG  G KGE           G+ G  G  G +G PG  G
Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 470  LRGITGIVGDKGEKGARGLDGEPGPQGLPGA--PGDQGQRGPPGEAGP------------ 515
            L G  G +GD G +G  G++G PGP GLPGA  PG  G RGPPG  G             
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 516  -----KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG----------- 559
                 KGD+G+ G  G  G PG  GD G PG  G  G PG+PG +G+PG           
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 560  -------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 612
                     GPPG  G +G PGV G PG   +    GS G PG PG+ G  G+PG  GPP
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 613  GEVGPRGPQGLPGS---------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 663
            G +GP GP+G PG           GE G  GS G PG  GS G PGL G  G  G P   
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 664  GDRGVV 669
              RG V
Sbjct: 1442 TTRGFV 1447



 Score =  337 bits (863), Expect = 4e-92
 Identities = 221/530 (41%), Positives = 258/530 (48%), Gaps = 69/530 (13%)

Query: 433 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 492
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 493 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 553 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 605 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 657
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 658 GLP--------GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
           GLP        G  GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 710 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 759
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 760 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGFPGQ 812
             +K       +     M        +G+ GLPG PGPPGPP       GPPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 813 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 855 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 899
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  273 bits (699), Expect = 4e-73
 Identities = 164/383 (42%), Positives = 188/383 (49%), Gaps = 42/383 (10%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---------KGPPGPPG 305
            LP  +       + GPPG  GP GP G PG PG  G+ G  GP         KG  GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP 365
              G PG PG PG PG  G  G  G DG PG  G KG+ G    P          PGP G 
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP----------PGPRGN 1184

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
            PG  G  G+ G  G  G PGR+G  G  GP GP G  GF  G P  P A  PG++G  G 
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRGP 1243

Query: 426  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
            PG RG  GA G  G PG     G +GD+G +G  G +GPPG  G  G  G +G  G  G 
Sbjct: 1244 PGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 486  RGLDGEPGPQGLPGAPGDQGQR------GPPGEAGPKGDRGAEGARG------IPGLPGP 533
             G  G+PG QG PG  G++G        GPPG  GPKG  G  G  G      +PG PGP
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 534  KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGA 593
             G  G PG+ G  G PG PG  G  G  G PG           G PG  G AGEKG+ G+
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGK---------DGKPGTPGPAGEKGNKGS 1413

Query: 594  PGKPGQMGNSGKPGQQGPPGEVG 616
             G+PG  G+ G PG +G  G+ G
Sbjct: 1414 KGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 513 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 569 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 680
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 681 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 734
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 735 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 785 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 833
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 834 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 881
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 882 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 2e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 643 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 703 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 762
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 763 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 817
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 818 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 851
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 852 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 893
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 894 PPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  131 bits (330), Expect = 3e-30
 Identities = 93/259 (35%), Positives = 108/259 (41%), Gaps = 78/259 (30%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGK 312
            LP  I P QT + RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G 
Sbjct: 1229 LPGAIIPGQTGN-RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287

Query: 313  PGAPGKPGTPGADGLTGPDGSPGSIGS---KGQKGEPGV---------------PGSRGF 354
             G PG+ G PG  GL GP G PG  G    KG+KG PG                PG RG 
Sbjct: 1288 MGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGD 1347

Query: 355  PGR----GIPGPPGPPGTAGLPGELGRVGPVGDPG------------------------- 385
            PG      +PG PGPPGT G PG  G  GP G PG                         
Sbjct: 1348 PGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE 1407

Query: 386  -----------------------RRGPPGPPGPPGPRGTIGFHDGD----PLCPNACPPG 418
                                   +RG  G P     RG +          P CP    P 
Sbjct: 1408 KGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPL 1467

Query: 419  RSGYPGLPGMRGHKGAKGE 437
             SG+  L  ++G++ A G+
Sbjct: 1468 YSGFSFL-FVQGNQRAHGQ 1485


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 269  GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 319
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 320  GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 379
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 380  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 439
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 440  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 482
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 483  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 522
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 523  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 573
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 574  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 627
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 628  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 679
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 680  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 715
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 716  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 770
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 771  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 820
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 821  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 867
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 868  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  498 bits (1283), Expect = e-141
 Identities = 327/815 (40%), Positives = 378/815 (46%), Gaps = 207/815 (25%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP-----------PGPPGPAGEPGKPGAPG 317
            GPPG  G PGP GPPG+PG  G  GD G  GP           PGPPGP G+ G PG  G
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 318  KPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPGR----------GIPGPPGP 365
              G PG  G  G  G PG  G+KG+     PG PG+ GFPG           G+PG PG 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG-----PRGTIGFHDGDPLCPNACPPGRS 420
            PGT   PG  G  GP GDPG+ GPPG  GPPG     PRG  G    + L       G++
Sbjct: 779  PGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKT 835

Query: 421  GYPGLPGMRG--HKGAKGEIGEPGRQGHKGEEGDQGELG---EVGAQGPPGAQGLRGITG 475
            G  G PG+ G    G  GE G PG  GH+GE G  G+ G     G  GPPG  G+ G+ G
Sbjct: 836  GPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG 895

Query: 476  IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR------GIPG 529
              G  G  G  G  G PG +G PG PG +GQRG PG  G +GD+G  G        G  G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 530  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGP---------------PGDAGLQGLPG 574
             PG KG  G PG  G  G+PGMPG KG  G PGP               PG+ GL+G+PG
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 575  V------------------------PGIPGAKGVAGEKGS--------------TGAPGK 596
                                     PG+PG  G+ G+KG               TG PG 
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 597  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG---------- 646
            PG MG  G+ GQ GPPG +GP GP+G PGS G  G  G PG  G LG  G          
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGI 1135

Query: 647  --SPGLPGLPGPPGLPGMKGDRGVVGEPGP-------------------------KGEQG 679
               PGLPG PG PG  G++GD+G  G PGP                         KG++G
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 680  ASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPGVEGP 728
            A G  G  G +G +GD G  GP G  G PG PGL           RGP GSRG PG  GP
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGP 1255

Query: 729  RGPPGPR--GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 786
             GPPG    G++G++G+ G PG +GPPG A                        +  P  
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTA----------------------GDMGPP-- 1291

Query: 787  GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGE---- 839
            G  G PG PG PGP G PG  GFPG  G +G PG  G   PPG +G +GP G  G+    
Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351

Query: 840  --------------------KGERGPPGR-------GPNGLPGAIGLPGDPGPASYGRNG 872
                                +GE GPPG        GP G PG  G PG PGPA  G  G
Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKG 1409

Query: 873  RDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 907
              G +G PG AG  G+PG  G  G  G   PA+ T
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG--SPATWT 1442



 Score =  490 bits (1261), Expect = e-138
 Identities = 327/815 (40%), Positives = 382/815 (46%), Gaps = 197/815 (24%)

Query: 253  HELPARITPSQTTDERGPPGEQGP--------PGPPGPPGVPGIDGIDGDRGPKGP---- 300
            H LP  +         GP GE G         PGPPG PG+PG+ G+ G  G +G     
Sbjct: 451  HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLK 510

Query: 301  --------------PGPPGPAGEP----------------GKPGAPGK------------ 318
                          PG PG  G+P                G PG PG             
Sbjct: 511  GSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGI 570

Query: 319  PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG---------------------R 357
            PGTPG  GL GP G     G KG +G PG PGS G PG                     +
Sbjct: 571  PGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQ 630

Query: 358  GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF------------- 404
            G+PG PGPPG AG  GEL    PV  PG  GPPGPPG PGP+G  G              
Sbjct: 631  GVPGAPGPPGEAGPRGELSVSTPV--PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688

Query: 405  -HDGDPLCPN---ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGE--LGE 458
              DG+P  P      PPG  G  G PG +G  G  G++GEPG  G  G  G +GE  +  
Sbjct: 689  GPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAM 748

Query: 459  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD 518
             G  G PG  G RG +G  G+ G  G  GL G PG +GL G  GD GQ GPPGE GP G 
Sbjct: 749  PGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR 808

Query: 519  --RGAEGARGIPGL------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 564
               G  GA+G+PGL             GPKGD G+PG+D R G PG  G+ G PG  G  
Sbjct: 809  CIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD-RSGFPGETGSPGIPGHQGEM 867

Query: 565  GDAGLQGLPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ 621
            G  G +G PG PGI   PG  GV G  G  GA G PG  GN G PGQ+G PG  G +G +
Sbjct: 868  GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 622  GLPGSRGE---------------LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 666
            G PG++GE               +G  G PGL G  G+ G  G  G+PG PGL G+KG  
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 667  GVVGEPGPKGEQGASGEEGEAGER---GELGDIGLPGPKGS---------AGNPGEPGLR 714
            G  G PGP+G+ G++G  GE G R   G +G++G+PG KG          AG PG PG+ 
Sbjct: 988  GPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIH 1047

Query: 715  GPEGSRGLPGVE-----GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRV 769
            G +G +G PG       GP GP G  G+ G+ G  G  G  GPPG               
Sbjct: 1048 GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPG--------------- 1092

Query: 770  IQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP----- 824
               H             GA G PG PG PG PGP G+ GF G  G+ G PGI+GP     
Sbjct: 1093 ---HLGPAG------PEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 825  ----PGALGLRGPK------GDLGEKGE----RGPPGRGPNGLPGAIGLPGDPG----PA 866
                PG +G+RG +      G  GEKGE    R PP  GP G PGA G  GD G    P 
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPP--GPRGNPGAQGAKGDRGAPGFPG 1201

Query: 867  SYGRNGRDGERGPPGVAGIPGVPGPPGPPG--LPG 899
              GR G  G+ GP G  GI G PGPPG PG  +PG
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPG 1236



 Score =  489 bits (1259), Expect = e-138
 Identities = 304/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 267  ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 324
            ERG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 325  DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 384
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 385  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 443
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 444  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 503
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 504  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 552
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 553  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 600
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 601  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 656
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 657  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 701
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 702  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 757
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 758  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 817
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 818  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 876
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 877  RGPPGVAGIPGVPGPPGPPGLPGFCEP 903
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1247), Expect = e-136
 Identities = 319/753 (42%), Positives = 372/753 (49%), Gaps = 112/753 (14%)

Query: 256  PARITPSQTTDERGPPGEQGPPGPPGPPGVPGI------------------DGIDGDRGP 297
            P+ +       E+G PG+ G  G PG  GVPG                   DGI G +G 
Sbjct: 275  PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334

Query: 298  KGPPGPPGPA---------GEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSK--GQKGEP 346
             GPPG  GP          G+ G PG PG  G  G  G +GP G PGS GS   G +G P
Sbjct: 335  IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAP 394

Query: 347  GVP------GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPG----RRGPPGPPGPP 396
            G P      G RG PG+   G PG PG AG PG  G  GP G PG    R+GPPG  G P
Sbjct: 395  GWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP 454

Query: 397  GPRGTIGF-----HDGDP-LCPNACP--PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 448
            G  G+ G        G+P L    CP  PG  G PGLPG+ G KG  G  G  G +G  G
Sbjct: 455  GYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPG 514

Query: 449  EEGD---QGELGEVGAQGPPGAQGLRGIT----GIVGDKGEKGARGLDGEPGPQGLPGAP 501
              G+    G  G  GAQG PG +G +G T    G VG  G+ G RG  G  G  G+PG P
Sbjct: 515  SPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTP 574

Query: 502  GDQGQRGPPGE---AGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 558
            G +G  GP GE   +G KGD+G  G  G PG PGP G  G PG  G  G PG+ GT+G P
Sbjct: 575  GVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVP 633

Query: 559  GKPGPPGDAGLQG----LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 614
            G PGPPG+AG +G       VPG PG  G  G  G  G PG PG +G  G PG  GP GE
Sbjct: 634  GAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGE 693

Query: 615  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP 674
             G  G  G PG  G  G  G PG  G LG  G  G PGLPG PGLPG KG+   V  PG 
Sbjct: 694  PGIPG-IGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE-PAVAMPGG 751

Query: 675  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP------GEPGLRGPEGSRGLPG--VE 726
             G  G  GE G +GE GE+G  GLPG  G+ GN       G+PG  GP G +G PG  +E
Sbjct: 752  PGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIE 811

Query: 727  GPRGP---PGPRGVQGEQGATGLPGVQGPPGRAPTDQ--HIKQVCMRVIQEHFAEMAASL 781
            GPRG    PG  G++G+QG  G  G +G PG    D+     +     I  H  EM    
Sbjct: 812  GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 782  KR------------PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 829
            +R             + G  G+ G PG  GPPGPPG  G PGQ G  G+PG+KG  G  G
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPG 931

Query: 830  LRGPKGD------------LGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS 867
             +G +GD            +G+KGE G  G          RG  G+PG  GL G PGPA 
Sbjct: 932  AKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAG 991

Query: 868  -YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 899
              G  G  G  G PG  G+ G+PG  G  G+PG
Sbjct: 992  PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024



 Score =  477 bits (1228), Expect = e-134
 Identities = 304/726 (41%), Positives = 367/726 (50%), Gaps = 124/726 (17%)

Query: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGAPG 317
           E+G  G  GPPG PG  G  G +G+ G +GPKG PG PG  G          PG  G+PG
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPG 106

Query: 318 KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG--------------------- 356
            PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG                     
Sbjct: 107 LPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIE 166

Query: 357 ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 413
              +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G H G+ +   
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG-HMGERVI-- 223

Query: 414 ACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 468
               G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE    GPPG  
Sbjct: 224 ----GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE---PGPPGPS 276

Query: 469 GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGPKGDRGAEGAR 525
           GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G  G +G +G  
Sbjct: 277 GLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI 335

Query: 526 GIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA--GLQGLPG 574
           G PG  GP         KGD G PG  G  G  G  G  G PG PG PG +  GL+G PG
Sbjct: 336 GPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG 395

Query: 575 VPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----RGPQGLPGSRG 628
            PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +GP   PG  G
Sbjct: 396 WPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP---PGDHG 452

Query: 629 ELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE 683
             G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P   G QGA+G 
Sbjct: 453 LPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP---GRQGAAGL 509

Query: 684 EGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPRGPPGPRGVQG 739
           +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G RG PG +G+ G
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDG 569

Query: 740 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 799
             G  G+ G+ GP G                     E+A S ++ D G  G PG PG PG
Sbjct: 570 IPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPPGDPGSPGSPG 608

Query: 800 PPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEKGERGPPG--- 847
           P GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  G  GPPG   
Sbjct: 609 PAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668

Query: 848 -RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 906
            +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G PG      C
Sbjct: 669 PQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQGFPGTKGSLGC 722

Query: 907 TMQAGQ 912
             + G+
Sbjct: 723 PGKMGE 728



 Score =  467 bits (1202), Expect = e-131
 Identities = 312/773 (40%), Positives = 371/773 (47%), Gaps = 150/773 (19%)

Query: 256 PARITPSQTTDERGPPGEQGPPGPPGPPGV---PGIDGIDGDRGPKGPP----------- 301
           P    P       G  G +G  G PG PG    PGI G  G +G KG P           
Sbjct: 111 PGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAK 170

Query: 302 GPPGPAGEPGKPGAPGKPGTPGADGLTGPD---GSPGSIGSKGQKGEPG--VPGSRGFPG 356
           G PG  G PG  G PG PG PG  G  GP    G PG++G +G KG  G  V G +G  G
Sbjct: 171 GDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERG 230

Query: 357 -RGIPGPPGPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPP 393
            +G+ GPPGPPGT             L GE G  G +G+PG  GP            G P
Sbjct: 231 VKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAP 290

Query: 394 GPPGPRGTIGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG------- 445
           G PG +G  G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G       
Sbjct: 291 GDPGLQGKPG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349

Query: 446 --HKGEEGDQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-- 484
              KG+EG  G  G  GA+GP                 PG +G  G  G+ G KGE+G  
Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409

Query: 485 ---ARGLDGEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPK 534
              A G  G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPK
Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469

Query: 535 GDTGL--------PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPG 577
           G+ GL        PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG
Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPG 529

Query: 578 IPGAKGVAGEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLP 624
             G  G+ GEKG T       G PG PG  G  G+ G  G PG        GP+G   L 
Sbjct: 530 AQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589

Query: 625 GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE- 683
           G +G+ GP G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE 
Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGEL 648

Query: 684 ---------EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPP 732
                     G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP 
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPK 708

Query: 733 GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 792
           G +G  G +G+ G PG  G PG                      +  +   P   A  +P
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMP 749

Query: 793 GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRG 849
           G PG PG PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR 
Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809

Query: 850 PNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 899
             G  GA GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  462 bits (1190), Expect = e-130
 Identities = 293/701 (41%), Positives = 344/701 (49%), Gaps = 134/701 (19%)

Query: 261  PSQTTDERGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---- 305
            P     + GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG    
Sbjct: 790  PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRS 849

Query: 306  -------------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEP 346
                               P G+ G PG PG  G PG DG+ G  G PG+IG  G  G P
Sbjct: 850  GFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909

Query: 347  GVPGSRGFPG-------------------RGIPGP------------PGPPGTAGLPGEL 375
            G PG RG PG                   +G PGP            PG  G AG PGE 
Sbjct: 910  GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEK 969

Query: 376  GRVGPVGDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGH 431
            G  G  G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G 
Sbjct: 970  GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGK 1028

Query: 432  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGAR 486
            +G  G  G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  
Sbjct: 1029 RGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP 1088

Query: 487  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 546
            G  G  GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  
Sbjct: 1089 GPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP 1148

Query: 547  GIPGMPGTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 602
            G  G+ G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G 
Sbjct: 1149 GPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGA 1208

Query: 603  SGKPGQQGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-- 658
             G  G +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  
Sbjct: 1209 MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSH 1262

Query: 659  LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 718
            + G+KGD+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G
Sbjct: 1263 VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKG 1322

Query: 719  SRGL------PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 772
            + G       PG  GP+GPPG RG  G      LPG  GPPG                  
Sbjct: 1323 NPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------- 1365

Query: 773  HFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG 832
                               PG PG  G PGPPG  G  G  G RG PG  G PG  G  G
Sbjct: 1366 -------------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406

Query: 833  PKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASYGRNG 872
             KG+ G KGE GP   G +GLPG  G  GD G PA++   G
Sbjct: 1407 EKGNKGSKGEPGP--AGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  337 bits (865), Expect = 2e-92
 Identities = 202/486 (41%), Positives = 237/486 (48%), Gaps = 87/486 (17%)

Query: 269  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 328
            G PGE+G  G PG PG+ G+ G+ G  GP GP G  G  G PG+PG  G PG+ G  G+ 
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 329  GPDGSPGSIGSKGQKGEPGVPGSRGFPG--------RGI-PGPPGPPGTAGLPGELGR-- 377
            G  G  G++G  G+ G PG+PG  G  G         G  PGPPGP G  GLPG++G+  
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 378  -------------VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGR 419
                          GP G PG  G PG PG PGP G +GF       G P      PPG 
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--PPGL 1141

Query: 420  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGE----------EGDQGELGEVGAQGPPGAQG 469
             G+PG PG  G +G +G  G PG  G KGE           G+ G  G  G +G PG  G
Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 470  LRGITGIVGDKGEKGARGLDGEPGPQGLPGA--PGDQGQRGPPGEAGP------------ 515
            L G  G +GD G +G  G++G PGP GLPGA  PG  G RGPPG  G             
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 516  -----KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG----------- 559
                 KGD+G+ G  G  G PG  GD G PG  G  G PG+PG +G+PG           
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 560  -------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 612
                     GPPG  G +G PGV G PG   +    GS G PG PG+ G  G+PG  GPP
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 613  GEVGPRGPQGLPGS---------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 663
            G +GP GP+G PG           GE G  GS G PG  GS G PGL G  G  G P   
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 664  GDRGVV 669
              RG V
Sbjct: 1442 TTRGFV 1447



 Score =  337 bits (863), Expect = 4e-92
 Identities = 221/530 (41%), Positives = 258/530 (48%), Gaps = 69/530 (13%)

Query: 433 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 492
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 493 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 552
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 553 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 604
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 605 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 657
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 658 GLP--------GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 709
           GLP        G  GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 710 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 759
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 760 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGFPGQ 812
             +K       +     M        +G+ GLPG PGPPGPP       GPPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 813 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 854
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 855 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 899
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  273 bits (699), Expect = 4e-73
 Identities = 164/383 (42%), Positives = 188/383 (49%), Gaps = 42/383 (10%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---------KGPPGPPG 305
            LP  +       + GPPG  GP GP G PG PG  G+ G  GP         KG  GPPG
Sbjct: 1075 LPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPG 1134

Query: 306  PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGP 365
              G PG PG PG PG  G  G  G DG PG  G KG+ G    P          PGP G 
Sbjct: 1135 IRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP----------PGPRGN 1184

Query: 366  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 425
            PG  G  G+ G  G  G PGR+G  G  GP GP G  GF  G P  P A  PG++G  G 
Sbjct: 1185 PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF-PGPPGLPGAIIPGQTGNRGP 1243

Query: 426  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 485
            PG RG  GA G  G PG     G +GD+G +G  G +GPPG  G  G  G +G  G  G 
Sbjct: 1244 PGSRGSPGAPGPPGPPGSH-VIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGL 1302

Query: 486  RGLDGEPGPQGLPGAPGDQGQR------GPPGEAGPKGDRGAEGARG------IPGLPGP 533
             G  G+PG QG PG  G++G        GPPG  GPKG  G  G  G      +PG PGP
Sbjct: 1303 PGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGP 1362

Query: 534  KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGA 593
             G  G PG+ G  G PG PG  G  G  G PG           G PG  G AGEKG+ G+
Sbjct: 1363 PGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGK---------DGKPGTPGPAGEKGNKGS 1413

Query: 594  PGKPGQMGNSGKPGQQGPPGEVG 616
             G+PG  G+ G PG +G  G+ G
Sbjct: 1414 KGEPGPAGSDGLPGLKGKRGDSG 1436



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 513 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 568
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 569 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 628
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 629 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 680
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 681 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 734
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 735 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 784
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 785 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 833
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 834 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 881
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 882 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 919
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 2e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 643 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 702
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 703 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 762
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 763 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 817
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 818 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 851
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 852 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 893
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 894 PPGLPGFCEPASCTMQAGQRAFNKGPDP 921
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  131 bits (330), Expect = 3e-30
 Identities = 93/259 (35%), Positives = 108/259 (41%), Gaps = 78/259 (30%)

Query: 255  LPARITPSQTTDERGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGK 312
            LP  I P QT + RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G 
Sbjct: 1229 LPGAIIPGQTGN-RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287

Query: 313  PGAPGKPGTPGADGLTGPDGSPGSIGS---KGQKGEPGV---------------PGSRGF 354
             G PG+ G PG  GL GP G PG  G    KG+KG PG                PG RG 
Sbjct: 1288 MGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGD 1347

Query: 355  PGR----GIPGPPGPPGTAGLPGELGRVGPVGDPG------------------------- 385
            PG      +PG PGPPGT G PG  G  GP G PG                         
Sbjct: 1348 PGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGE 1407

Query: 386  -----------------------RRGPPGPPGPPGPRGTIGFHDGD----PLCPNACPPG 418
                                   +RG  G P     RG +          P CP    P 
Sbjct: 1408 KGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPL 1467

Query: 419  RSGYPGLPGMRGHKGAKGE 437
             SG+  L  ++G++ A G+
Sbjct: 1468 YSGFSFL-FVQGNQRAHGQ 1485


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.144    0.464 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,035,658
Number of Sequences: 37866
Number of extensions: 5777467
Number of successful extensions: 247132
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 531
Number of HSP's successfully gapped in prelim test: 1575
Number of HSP's that attempted gapping in prelim test: 22918
Number of HSP's gapped (non-prelim): 28918
length of query: 921
length of database: 18,247,518
effective HSP length: 112
effective length of query: 809
effective length of database: 14,006,526
effective search space: 11331279534
effective search space used: 11331279534
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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