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Search of human proteins with 5802970
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
(797 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] 1605 0.0
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] 522 e-148
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 354 2e-97
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 354 2e-97
gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens] 217 3e-56
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] 213 6e-55
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 210 4e-54
gi|6005942 valosin-containing protein [Homo sapiens] 199 1e-50
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 197 4e-50
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 194 3e-49
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 188 1e-47
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ... 186 7e-47
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi... 186 7e-47
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] 186 7e-47
gi|157671927 spermatogenesis associated 5 [Homo sapiens] 181 3e-45
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 178 2e-44
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 178 2e-44
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 172 1e-42
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 166 8e-41
gi|4505725 peroxin1 [Homo sapiens] 152 9e-37
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens] 151 3e-36
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens] 151 3e-36
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap... 151 3e-36
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 141 3e-33
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 140 5e-33
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 140 5e-33
gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 134 4e-31
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 133 6e-31
gi|40806170 spastin isoform 2 [Homo sapiens] 131 3e-30
gi|11875211 spastin isoform 1 [Homo sapiens] 131 3e-30
>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
Length = 797
Score = 1605 bits (4156), Expect = 0.0
Identities = 797/797 (100%), Positives = 797/797 (100%)
Query: 1 MAHRCLRLWGRGGCWPRGLQQLLVPGGVGPGEQPCLRTLYRFVTTQARASRNSLLTDIIA 60
MAHRCLRLWGRGGCWPRGLQQLLVPGGVGPGEQPCLRTLYRFVTTQARASRNSLLTDIIA
Sbjct: 1 MAHRCLRLWGRGGCWPRGLQQLLVPGGVGPGEQPCLRTLYRFVTTQARASRNSLLTDIIA 60
Query: 61 AYQRFCSRPPKGFGKYFPNGKNGKKASEPKEVMGEKKESKPAATTRSSGGGGGGGGKRGG 120
AYQRFCSRPPKGFGKYFPNGKNGKKASEPKEVMGEKKESKPAATTRSSGGGGGGGGKRGG
Sbjct: 61 AYQRFCSRPPKGFGKYFPNGKNGKKASEPKEVMGEKKESKPAATTRSSGGGGGGGGKRGG 120
Query: 121 KKDDSHWWSRFQKGDIPWDDKDFRMFFLWTALFWGGVMFYLLLKRSGREITWKDFVNNYL 180
KKDDSHWWSRFQKGDIPWDDKDFRMFFLWTALFWGGVMFYLLLKRSGREITWKDFVNNYL
Sbjct: 121 KKDDSHWWSRFQKGDIPWDDKDFRMFFLWTALFWGGVMFYLLLKRSGREITWKDFVNNYL 180
Query: 181 SKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENR 240
SKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENR
Sbjct: 181 SKGVVDRLEVVNKRFVRVTFTPGKTPVDGQYVWFNIGSVDTFERNLETLQQELGIEGENR 240
Query: 241 VPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLK 300
VPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLK
Sbjct: 241 VPVVYIAESDGSFLLSMLPTVLIIAFLLYTIRRGPAGIGRTGRGMGGLFSVGETTAKVLK 300
Query: 301 DEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKA 360
DEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKA
Sbjct: 301 DEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKA 360
Query: 361 TAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGN 420
TAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGN
Sbjct: 361 TAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGN 420
Query: 421 FGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDI 480
FGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDI
Sbjct: 421 FGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDI 480
Query: 481 KGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSI 540
KGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSI
Sbjct: 481 KGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSI 540
Query: 541 NQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRG 600
NQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRG
Sbjct: 541 NQKHFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRG 600
Query: 601 KGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRASEEIFFGRITTGAQDDLRKVTQSAYAQ 660
KGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRASEEIFFGRITTGAQDDLRKVTQSAYAQ
Sbjct: 601 KGLGYAQYLPKEQYLYTKEQLLDRMCMTLGGRASEEIFFGRITTGAQDDLRKVTQSAYAQ 660
Query: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720
IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK
Sbjct: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720
Query: 721 ADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEFVEGTGSLDEDTSLPEGLKDWN 780
ADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEFVEGTGSLDEDTSLPEGLKDWN
Sbjct: 721 ADVEKVALLLLEKEVLDKNDMVELLGPRPFAEKSTYEEFVEGTGSLDEDTSLPEGLKDWN 780
Query: 781 KEREKEKEEPPGEKVAN 797
KEREKEKEEPPGEKVAN
Sbjct: 781 KEREKEKEEPPGEKVAN 797
>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
Length = 795
Score = 522 bits (1345), Expect = e-148
Identities = 298/644 (46%), Positives = 407/644 (63%), Gaps = 31/644 (4%)
Query: 163 LKRSGREITWKDFVNNYLSKGVVDRLEVVNKR-FVRVTFTPGKT----PVDGQYVWFNIG 217
L SG I+W DFV+ L+KG V R++VV + V V PG P +
Sbjct: 158 LSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVA 217
Query: 218 SVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRGPA 276
++D FE L + EL IE ++R+PV Y G+ L S+ T + +A L Y R
Sbjct: 218 NIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLA-- 275
Query: 277 GIGRTGRGMGGLFSVGETTAKVLKDEID------VKFKDVAGCEEAKLEIMEFVNFLKNP 330
G TGR G FS +D V FKDVAG EAKLE+ EFV++LK+P
Sbjct: 276 --GMTGREGG--FSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSP 331
Query: 331 KQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVR 390
+++ LGAK+PKGA+L GPPG GKTLLAKA A EA VPF+ ++G EF+E+ G+G ARVR
Sbjct: 332 ERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVR 391
Query: 391 DLFALARKNAPCILFIDEIDAVGRKRGRGNFG-GQSEQENTLNQLLVEMDGFNTTTNVVI 449
LF AR APCI++IDEIDAVG+KR G +E+E TLNQLLVEMDG TT +V++
Sbjct: 392 SLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGMGTTDHVIV 451
Query: 450 LAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKL 509
LA TNR DILD AL+RPGR DR +FI P ++ R IF+ HL+ LKL T +++L
Sbjct: 452 LASTNRADILDGALMRPGRLDRHVFIDLPTLQERREIFEQHLKSLKL--TQSSTFYSQRL 509
Query: 510 ASLTPGFSGADVANVCNEAALIAARHLSDSINQKHFEQAIERVIGGLEKKTQVLQPEEKK 569
A LTPGFSGAD+AN+CNEAAL AAR S++ +FE A+ERV+ G KK+++L EE+K
Sbjct: 510 AELTPGFSGADIANICNEAALHAAREGHTSVHTLNFEYAVERVLAGTAKKSKILSKEEQK 569
Query: 570 TVAYHEAGHAVAGWYLEHADPLLKVSIIPR-GKGLGYAQYLPKEQYLYTKEQLLDRMCMT 628
VA+HE+GHA+ GW LEH + ++KVSI PR LG+AQ LP++Q+L+TKEQL +RMCM
Sbjct: 570 VVAFHESGHALVGWMLEHTEAVMKVSITPRTNAALGFAQMLPRDQHLFTKEQLFERMCMA 629
Query: 629 LGGRASEEIFFGRITTGAQDDLRKVTQSAYAQIVQFGMNEKVGQISFDLPRQGDM-VLEK 687
LGGRASE + F +T+GAQDDLRKVT+ AY+ + QFGM +G ISF ++G M + +
Sbjct: 630 LGGRASEALSFNEVTSGAQDDLRKVTRIAYSMVKQFGMAPGIGPISFPEAQEGLMGIGRR 689
Query: 688 PYSEATARLIDDEVRILINDAYKRTVALLTEKKADVEKVALLLLEKEVLDKNDMVELLGP 747
P+S+ +++D E R+L+ AY+ T +L + ++ +A LLEKEV++ D+ L+GP
Sbjct: 690 PFSQGLQQMMDHEARLLVAKAYRHTEKVLQDNLDKLQALANALLEKEVINYEDIEALIGP 749
Query: 748 RPFAEKSTYEEFVEGTGSLDEDTSLPEGLKDWNKEREKEKEEPP 791
P K + + +D +D +E +E ++PP
Sbjct: 750 PPHGPK----KMIAPQRWIDAQRE----KQDLGEEETEETQQPP 785
>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
Length = 773
Score = 354 bits (908), Expect = 2e-97
Identities = 192/441 (43%), Positives = 280/441 (63%), Gaps = 17/441 (3%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
+V F+ V G EEAK E+ E V FLKNP+++ LG K+PKG +L GPPGTGKTLLA+A AG
Sbjct: 335 NVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 394
Query: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423
EA+VPF SGSEF EMFVGVG +R+R+LF A+ NAPC++FIDE+D+VG KR
Sbjct: 395 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 454
Query: 424 QSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
S Q T+NQLL EMDGF V+I+ TN P+ LD AL+RPGRFD Q+ + PD+KGR
Sbjct: 455 YSRQ--TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 512
Query: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
I K +L +K D +++ + +AR T GFSGA++ N+ N+AAL AA + + K
Sbjct: 513 TEILKWYLNKIKFDQSVDPEIIARG----TVGFSGAELENLVNQAALKAAVDGKEMVTMK 568
Query: 544 HFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGL 603
E + ++++ G E+++ + + K AYHE+GHA+ +Y + A P+ K +I+PRG L
Sbjct: 569 ELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTL 628
Query: 604 GYAQYLPK-EQYLYTKEQLLDRMCMTLGGRASEEIFFG--RITTGAQDDLRKVTQSAYAQ 660
G+ LP+ +++ T+ QLL +M +++GGR +EE+ FG ITTGA D T+ A
Sbjct: 629 GHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRM 688
Query: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720
+ +FGM+EK+G +++ + S T I+ E+RIL+ D+Y+R +L
Sbjct: 689 VTKFGMSEKLGVMTYSDTGK--------LSPETQSAIEQEIRILLRDSYERAKHILKTHA 740
Query: 721 ADVEKVALLLLEKEVLDKNDM 741
+ + +A LL E LD ++
Sbjct: 741 KEHKNLAEALLTYETLDAKEI 761
>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
Length = 716
Score = 354 bits (908), Expect = 2e-97
Identities = 192/441 (43%), Positives = 280/441 (63%), Gaps = 17/441 (3%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
+V F+ V G EEAK E+ E V FLKNP+++ LG K+PKG +L GPPGTGKTLLA+A AG
Sbjct: 278 NVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAG 337
Query: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423
EA+VPF SGSEF EMFVGVG +R+R+LF A+ NAPC++FIDE+D+VG KR
Sbjct: 338 EADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPMHP 397
Query: 424 QSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
S Q T+NQLL EMDGF V+I+ TN P+ LD AL+RPGRFD Q+ + PD+KGR
Sbjct: 398 YSRQ--TINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKGR 455
Query: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
I K +L +K D +++ + +AR T GFSGA++ N+ N+AAL AA + + K
Sbjct: 456 TEILKWYLNKIKFDQSVDPEIIARG----TVGFSGAELENLVNQAALKAAVDGKEMVTMK 511
Query: 544 HFEQAIERVIGGLEKKTQVLQPEEKKTVAYHEAGHAVAGWYLEHADPLLKVSIIPRGKGL 603
E + ++++ G E+++ + + K AYHE+GHA+ +Y + A P+ K +I+PRG L
Sbjct: 512 ELEFSKDKILMGPERRSVEIDNKNKTITAYHESGHAIIAYYTKDAMPINKATIMPRGPTL 571
Query: 604 GYAQYLPK-EQYLYTKEQLLDRMCMTLGGRASEEIFFG--RITTGAQDDLRKVTQSAYAQ 660
G+ LP+ +++ T+ QLL +M +++GGR +EE+ FG ITTGA D T+ A
Sbjct: 572 GHVSLLPENDRWNETRAQLLAQMDVSMGGRVAEELIFGTDHITTGASSDFDNATKIAKRM 631
Query: 661 IVQFGMNEKVGQISFDLPRQGDMVLEKPYSEATARLIDDEVRILINDAYKRTVALLTEKK 720
+ +FGM+EK+G +++ + S T I+ E+RIL+ D+Y+R +L
Sbjct: 632 VTKFGMSEKLGVMTYSDTGK--------LSPETQSAIEQEIRILLRDSYERAKHILKTHA 683
Query: 721 ADVEKVALLLLEKEVLDKNDM 741
+ + +A LL E LD ++
Sbjct: 684 KEHKNLAEALLTYETLDAKEI 704
>gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]
Length = 489
Score = 217 bits (553), Expect = 3e-56
Identities = 135/291 (46%), Positives = 173/291 (59%), Gaps = 19/291 (6%)
Query: 163 LKRSGREITWKDFVNNYLSKGVVDRLEVVNKR-FVRVTFTPGKT----PVDGQYVWFNIG 217
L SG I+W DFV+ L+KG V R++VV + V V PG P +
Sbjct: 158 LSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVA 217
Query: 218 SVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRGPA 276
++D FE L + EL IE ++R+PV Y G+ L S+ T + +A L Y R
Sbjct: 218 NIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLA-- 275
Query: 277 GIGRTGRGMGGLFSVGETTAKVLKDEID------VKFKDVAGCEEAKLEIMEFVNFLKNP 330
G TGR G FS +D V FKDVAG EAKLE+ EFV++LK+P
Sbjct: 276 --GMTGREGG--FSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSP 331
Query: 331 KQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVR 390
+++ LGAK+PKGA+L GPPG GKTLLAKA A EA VPF+ ++G EF+E+ G+G ARVR
Sbjct: 332 ERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVR 391
Query: 391 DLFALARKNAPCILFIDEIDAVGRKRGRGNFG-GQSEQENTLNQLLVEMDG 440
LF AR APCI++IDEIDAVG+KR G +E+E TLNQLLVEMDG
Sbjct: 392 SLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDG 442
>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
Length = 406
Score = 213 bits (542), Expect = 6e-55
Identities = 111/251 (44%), Positives = 158/251 (62%), Gaps = 5/251 (1%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
D ++ + G ++ EI E + +K+P+ ++ LG PKG +L GPPGTGKTLLA+A A
Sbjct: 145 DSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVA 204
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
+ FI VSGSE ++ F+G G VR+LF +AR++AP I+F+DEID++G R G G
Sbjct: 205 HHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSG 264
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
G SE + T+ +LL ++DGF T N+ ++ TNR DILD ALLRPGR DR+I PP+ +
Sbjct: 265 GDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEEA 324
Query: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQ 542
R I K+H R + L + RK+A L PG SGA+V VC EA + A R + Q
Sbjct: 325 RLDILKIHSRKMNLTRGIN----LRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQ 380
Query: 543 KHFEQAIERVI 553
+ FE A+ +V+
Sbjct: 381 EDFEMAVAKVM 391
>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
Length = 433
Score = 210 bits (535), Expect = 4e-54
Identities = 110/265 (41%), Positives = 163/265 (61%), Gaps = 5/265 (1%)
Query: 295 TAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTG 353
T ++++ DV + DV GC+E ++ E V L +P+++ +LG + PKG +L GPPGTG
Sbjct: 162 TMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTG 221
Query: 354 KTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVG 413
KTL A+A A + FI V GSE ++ +VG G VR+LF +AR C++F DEIDA+G
Sbjct: 222 KTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIG 281
Query: 414 RKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQI 473
R GG +E + T+ +L+ ++DGF+ N+ +L TNRPD LDPAL+RPGR DR+I
Sbjct: 282 GARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKI 341
Query: 474 FIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAA 533
PD++GR IFK+H R + ++E+D LA L P +GA++ +VC EA + A
Sbjct: 342 EFSLPDLEGRTHIFKIHARSM----SVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
Query: 534 RHLSDSINQKHFEQAIERVIGGLEK 558
R +K F +A+ +VI K
Sbjct: 398 RARRKIATEKDFLEAVNKVIKSYAK 422
>gi|6005942 valosin-containing protein [Homo sapiens]
Length = 806
Score = 199 bits (505), Expect = 1e-50
Identities = 106/237 (44%), Positives = 146/237 (61%), Gaps = 7/237 (2%)
Query: 305 VKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
V ++D+ G E+ K E+ E V + +++P ++ G KG + GPPG GKTLLAKA A
Sbjct: 474 VTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIAN 533
Query: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG- 422
E FI++ G E L M+ G A VR++F AR+ APC+LF DE+D++ + RG GN G
Sbjct: 534 ECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARG-GNIGD 592
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
G + +NQ+L EMDG +T NV I+ TNRPDI+DPA+LRPGR D+ I+I PD K
Sbjct: 593 GGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKS 652
Query: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDS 539
R +I K +LR S + KD LA +T GFSGAD+ +C A +A R +S
Sbjct: 653 RVAILKANLR----KSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIES 705
Score = 180 bits (456), Expect = 5e-45
Identities = 97/239 (40%), Positives = 147/239 (61%), Gaps = 8/239 (3%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
+V + D+ GC + +I E V L++P ++ +G K P+G +L GPPGTGKTL+A+A A
Sbjct: 200 EVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVA 259
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
E F ++G E + G + +R F A KNAP I+FIDE+DA+ KR + +
Sbjct: 260 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTH-- 317
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
G+ E+ ++QLL MDG +V+++A TNRP+ +DPAL R GRFDR++ IG PD G
Sbjct: 318 GEVER-RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376
Query: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541
R I ++H + +KL ++ +++A + T G GAD+A +C+EAAL A R D I+
Sbjct: 377 RLEILQIHTKNMKLADDVDLEQVANE----THGHVGADLAALCSEAALQAIRKKMDLID 431
>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
Length = 440
Score = 197 bits (500), Expect = 4e-50
Identities = 105/248 (42%), Positives = 153/248 (61%), Gaps = 5/248 (2%)
Query: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365
+ D+ G + EI E V L +P+ Y+++G K PKG IL GPPGTGKTLLAKA A +
Sbjct: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243
Query: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425
+ F+ V GSE ++ ++G GP VR+LF +A ++AP I+FIDEIDA+G KR N GG+
Sbjct: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303
Query: 426 EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRAS 485
E + T+ +LL ++DGF++ +V ++ TNR + LDPAL+RPGR DR+I PD K +
Sbjct: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363
Query: 486 IFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQKHF 545
IF++H + TL D L SGAD+ +C EA L+A R + + F
Sbjct: 364 IFQIHTSRM----TLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDF 419
Query: 546 EQAIERVI 553
+++ E V+
Sbjct: 420 KKSKENVL 427
>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
Length = 403
Score = 194 bits (493), Expect = 3e-49
Identities = 101/254 (39%), Positives = 153/254 (60%), Gaps = 5/254 (1%)
Query: 300 KDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLA 358
+D +V + ++ G E E+ E + L NP+ +Q +G PKG +L GPPGTGKTLLA
Sbjct: 139 EDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLA 198
Query: 359 KATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGR 418
+A A + + F+ V S ++ ++G +R++F AR + PCI+F+DEIDA+G +R
Sbjct: 199 RAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFS 258
Query: 419 GNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPP 478
E + TL +LL +MDGF+T V ++ TNRPD LDPALLRPGR DR+I I P
Sbjct: 259 EGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLP 318
Query: 479 DIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSD 538
+ + R I K+H P+ ++ + + + L+ GF+GAD+ NVC EA + A R D
Sbjct: 319 NEQARLDILKIHAGPITKHGEIDYEAIVK----LSDGFNGADLRNVCTEAGMFAIRADHD 374
Query: 539 SINQKHFEQAIERV 552
+ Q+ F +A+ +V
Sbjct: 375 FVVQEDFMKAVRKV 388
>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
Length = 439
Score = 188 bits (478), Expect = 1e-47
Identities = 103/265 (38%), Positives = 159/265 (60%), Gaps = 9/265 (3%)
Query: 293 ETTAKVLKDEIDVK----FKDVAGCEEAKLEIMEFVNFLKNPKQ-YQDLGAKIPKGAILT 347
E ++V E+D + + D+ G ++ E++E + N K+ +++LG + PKG ++
Sbjct: 167 EYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMY 226
Query: 348 GPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFID 407
GPPGTGKTLLA+A A + F+ ++G + ++MF+G G VRD FALA++ AP I+FID
Sbjct: 227 GPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFID 286
Query: 408 EIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPG 467
E+DA+G KR G E + T+ +LL ++DGF T V ++A TNR DILDPALLR G
Sbjct: 287 ELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDILDPALLRSG 346
Query: 468 RFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNE 527
R DR+I P+ + RA I ++H R + + + ++LAR T F+GA VC E
Sbjct: 347 RLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELAR----CTDDFNGAQCKAVCVE 402
Query: 528 AALIAARHLSDSINQKHFEQAIERV 552
A +IA R + + + + + I V
Sbjct: 403 AGMIALRRGATELTHEDYMEGILEV 427
>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
[Homo sapiens]
Length = 414
Score = 186 bits (472), Expect = 7e-47
Identities = 104/252 (41%), Positives = 148/252 (58%), Gaps = 7/252 (2%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
DV + D+ G + K E+ E V L + + Y+ +G P+G ++ GPPG GKT+LAKA A
Sbjct: 157 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 216
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
FI V GSEF++ ++G GP VRD+F LA++NAP I+FIDEIDA+ KR G
Sbjct: 217 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 276
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
E + L +LL +MDGF+ NV ++ TNR D LDPALLRPGR DR+I PD +
Sbjct: 277 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 336
Query: 483 RASIFKVHLRPLKLDSTLE-KDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541
+ IF + L ++ +D +AR SGAD+ ++C E+ ++A R +
Sbjct: 337 KRLIFSTITSKMNLSEEVDLEDYVAR-----PDKISGADINSICQESGMLAVRENRYIVL 391
Query: 542 QKHFEQAIERVI 553
K FE+A + VI
Sbjct: 392 AKDFEKAYKTVI 403
>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
sapiens]
Length = 387
Score = 186 bits (472), Expect = 7e-47
Identities = 104/252 (41%), Positives = 148/252 (58%), Gaps = 7/252 (2%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
DV + D+ G + K E+ E V L + + Y+ +G P+G ++ GPPG GKT+LAKA A
Sbjct: 130 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 189
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
FI V GSEF++ ++G GP VRD+F LA++NAP I+FIDEIDA+ KR G
Sbjct: 190 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 249
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
E + L +LL +MDGF+ NV ++ TNR D LDPALLRPGR DR+I PD +
Sbjct: 250 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 309
Query: 483 RASIFKVHLRPLKLDSTLE-KDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541
+ IF + L ++ +D +AR SGAD+ ++C E+ ++A R +
Sbjct: 310 KRLIFSTITSKMNLSEEVDLEDYVAR-----PDKISGADINSICQESGMLAVRENRYIVL 364
Query: 542 QKHFEQAIERVI 553
K FE+A + VI
Sbjct: 365 AKDFEKAYKTVI 376
>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
Length = 418
Score = 186 bits (472), Expect = 7e-47
Identities = 104/252 (41%), Positives = 148/252 (58%), Gaps = 7/252 (2%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
DV + D+ G + K E+ E V L + + Y+ +G P+G ++ GPPG GKT+LAKA A
Sbjct: 161 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 220
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
FI V GSEF++ ++G GP VRD+F LA++NAP I+FIDEIDA+ KR G
Sbjct: 221 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 280
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
E + L +LL +MDGF+ NV ++ TNR D LDPALLRPGR DR+I PD +
Sbjct: 281 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 340
Query: 483 RASIFKVHLRPLKLDSTLE-KDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541
+ IF + L ++ +D +AR SGAD+ ++C E+ ++A R +
Sbjct: 341 KRLIFSTITSKMNLSEEVDLEDYVAR-----PDKISGADINSICQESGMLAVRENRYIVL 395
Query: 542 QKHFEQAIERVI 553
K FE+A + VI
Sbjct: 396 AKDFEKAYKTVI 407
>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
Length = 893
Score = 181 bits (458), Expect = 3e-45
Identities = 100/255 (39%), Positives = 151/255 (59%), Gaps = 8/255 (3%)
Query: 301 DEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAK 359
D +V + D+ G E KL++ + V + LK+P+ + +G + PKG +L GPPG KT++AK
Sbjct: 620 DVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAK 679
Query: 360 ATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRG 419
A A E+ + F+ + G E + +VG VR+ F AR AP I+F DE+DA+ +RG
Sbjct: 680 ALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERG-S 738
Query: 420 NFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPD 479
+ G + + L QLL EMDG +V ILA TNRPD +D AL+RPGR DR I++ PD
Sbjct: 739 SLGAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPD 798
Query: 480 IKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARH--LS 537
R IFK+ + + + ++ D+L + T +SGA++ VC EAAL+A +
Sbjct: 799 AATRREIFKLQFHSMPVSNEVDLDELILQ----TDAYSGAEIVAVCREAALLALEEDIQA 854
Query: 538 DSINQKHFEQAIERV 552
+ I ++HF QA+ V
Sbjct: 855 NLIMKRHFTQALSTV 869
Score = 144 bits (364), Expect = 2e-34
Identities = 91/253 (35%), Positives = 139/253 (54%), Gaps = 12/253 (4%)
Query: 289 FSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILT 347
F+ + +K ++ V + + G I E + LK P+ ++ G P+G +L
Sbjct: 334 FTEIDKNSKEQDNQFKVTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLY 393
Query: 348 GPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFID 407
GPPGTGKT++A+A A E ++G E + F G A++R +FA A P I+FID
Sbjct: 394 GPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFID 453
Query: 408 EIDAVGRKRGRGNFGGQSE-QENTLNQLLVEMDGFNTTTN---VVILAGTNRPDILDPAL 463
E+DA+ KR G Q+E ++ + LL MDG + + V++L TNRP LD AL
Sbjct: 454 ELDALCPKRE----GAQNEVEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAAL 509
Query: 464 LRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVAN 523
RPGRFD++I IG P+ + R I + LR ++ L + +L +LA+ G+ GAD+
Sbjct: 510 RRPGRFDKEIEIGVPNAQDRLDILQKLLR--RVPHLLTEAELL-QLANSAHGYVGADLKV 566
Query: 524 VCNEAALIAARHL 536
+CNEA L A R +
Sbjct: 567 LCNEAGLCALRRI 579
>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
Length = 750
Score = 178 bits (452), Expect = 2e-44
Identities = 107/277 (38%), Positives = 157/277 (56%), Gaps = 24/277 (8%)
Query: 304 DVKFKDVAGCEEAKLEI-MEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
+V + D+ E+ + E+ M + ++NP Q++ LG P G +L GPPG GKTLLAKA A
Sbjct: 471 NVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVA 530
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
E+ + FI+V G E L M+VG VR +F A+ +APC++F DE+DA+ +R G
Sbjct: 531 NESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETG 590
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
+NQLL EMDG V I+A TNRPDI+DPA+LRPGR D+ +F+G P
Sbjct: 591 A---SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 647
Query: 483 RASIFKVHLR-----PLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIA----- 532
R +I K + PL D LE +A L ++GAD++ + EA++ A
Sbjct: 648 RLAILKTITKNGTKPPLDADVNLE--AIAGDLR--CDCYTGADLSALVREASICALRQEM 703
Query: 533 ARHLSDS------INQKHFEQAIERVIGGLEKKTQVL 563
AR S + ++ KHFE+A ++V + KK Q++
Sbjct: 704 ARQKSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIM 740
Score = 172 bits (435), Expect = 1e-42
Identities = 98/236 (41%), Positives = 135/236 (57%), Gaps = 10/236 (4%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
+VKF+DV G + E+ + + +++P+ Y LG P+G +L GPPG GKTLLA A AG
Sbjct: 155 NVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAG 214
Query: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423
E ++P + V+ E + G ++R+LF A NAPCI+FIDEIDA+ KR
Sbjct: 215 ELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR---EVAS 271
Query: 424 QSEQENTLNQLLVEMDGFN---TTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDI 480
+ + + QLL MD N T V+++ TNRPD LDPAL R GRFDR+I +G PD
Sbjct: 272 KDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDE 331
Query: 481 KGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHL 536
R I + R L+L + LA LTPGF GAD+ +C EAA+ A +
Sbjct: 332 ASRERILQTLCRKLRLPQAFD----FCHLAHLTPGFVGADLMALCREAAMCAVNRV 383
>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
Length = 856
Score = 178 bits (452), Expect = 2e-44
Identities = 107/277 (38%), Positives = 157/277 (56%), Gaps = 24/277 (8%)
Query: 304 DVKFKDVAGCEEAKLEI-MEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362
+V + D+ E+ + E+ M + ++NP Q++ LG P G +L GPPG GKTLLAKA A
Sbjct: 577 NVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVA 636
Query: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422
E+ + FI+V G E L M+VG VR +F A+ +APC++F DE+DA+ +R G
Sbjct: 637 NESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETG 696
Query: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482
+NQLL EMDG V I+A TNRPDI+DPA+LRPGR D+ +F+G P
Sbjct: 697 A---SVRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPAD 753
Query: 483 RASIFKVHLR-----PLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIA----- 532
R +I K + PL D LE +A L ++GAD++ + EA++ A
Sbjct: 754 RLAILKTITKNGTKPPLDADVNLE--AIAGDLR--CDCYTGADLSALVREASICALRQEM 809
Query: 533 ARHLSDS------INQKHFEQAIERVIGGLEKKTQVL 563
AR S + ++ KHFE+A ++V + KK Q++
Sbjct: 810 ARQKSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIM 846
Score = 172 bits (435), Expect = 1e-42
Identities = 98/236 (41%), Positives = 135/236 (57%), Gaps = 10/236 (4%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAG 363
+VKF+DV G + E+ + + +++P+ Y LG P+G +L GPPG GKTLLA A AG
Sbjct: 261 NVKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAG 320
Query: 364 EANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGG 423
E ++P + V+ E + G ++R+LF A NAPCI+FIDEIDA+ KR
Sbjct: 321 ELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKR---EVAS 377
Query: 424 QSEQENTLNQLLVEMDGFN---TTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDI 480
+ + + QLL MD N T V+++ TNRPD LDPAL R GRFDR+I +G PD
Sbjct: 378 KDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDE 437
Query: 481 KGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHL 536
R I + R L+L + LA LTPGF GAD+ +C EAA+ A +
Sbjct: 438 ASRERILQTLCRKLRLPQAFD----FCHLAHLTPGFVGADLMALCREAAMCAVNRV 489
>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
Length = 980
Score = 172 bits (435), Expect = 1e-42
Identities = 95/232 (40%), Positives = 140/232 (60%), Gaps = 8/232 (3%)
Query: 305 VKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGE 364
V + DV G +E K EI+E + + LG + G +L GPPGTGKTLLAKA A E
Sbjct: 702 VSWHDVGGLQEVKKEILETIQLPLEHPELLSLGLR-RSGLLLHGPPGTGKTLLAKAVATE 760
Query: 365 ANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGR-GNFGG 423
++ F++V G E + M+VG VR++FA AR APCI+F DE+D++ RGR G+ GG
Sbjct: 761 CSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGDSGG 820
Query: 424 QSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGP-PDIKG 482
+ ++QLL E+DG ++T +V ++ TNRPD+LDPALLRPGRFD+ +F+G D
Sbjct: 821 --VMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDRAS 878
Query: 483 RASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAAR 534
+ + R KL+ ++ L L P +GAD+ ++C++A A +
Sbjct: 879 QLRVLSAITRKFKLEPSV---SLVNVLDCCPPQLTGADLYSLCSDAMTAALK 927
Score = 57.0 bits (136), Expect = 7e-08
Identities = 48/183 (26%), Positives = 79/183 (43%), Gaps = 12/183 (6%)
Query: 341 PKGAILTG--------PPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDL 392
P GA+LTG PPG GKT + A + + V S G +++ +
Sbjct: 455 PGGALLTGTSSVLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAI 514
Query: 393 FALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAG 452
F+ AR+ P +L + +D +G R R G + L LL+ D N+ ++++A
Sbjct: 515 FSRARRCRPAVLLLTAVDLLG--RDRDGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVAT 572
Query: 453 TNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASL 512
T+R L PA ++ F ++ + R SI + L L + +LAR+ A
Sbjct: 573 TSRAQDL-PADVQTA-FPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGF 630
Query: 513 TPG 515
G
Sbjct: 631 VVG 633
>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
Length = 753
Score = 166 bits (420), Expect = 8e-41
Identities = 109/290 (37%), Positives = 159/290 (54%), Gaps = 32/290 (11%)
Query: 299 LKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLL 357
L D V ++++ G E+ KL++ + + + LK P ++ +G PKG +L GPPG KT L
Sbjct: 455 LMDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVLLYGPPGCAKTTL 514
Query: 358 AKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRG 417
+A A + F++VSG++ FVG + +F AR + P ILF+DEID++ R
Sbjct: 515 VRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARS 574
Query: 418 RGNFGGQSEQENTLNQLLVEMDGFNTTT-------------------NVVILAGTNRPDI 458
G QE L+ LL E+DG T +V+I+A TNRPD+
Sbjct: 575 ASK-TGCDVQERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDV 633
Query: 459 LDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLR--PLKLDSTLEKDKLARKLASLTPGF 516
LD ALLRPGR D+ I+I PPD KGR SI KV + P+ D +LE LA+ T F
Sbjct: 634 LDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLE------NLAAETCFF 687
Query: 517 SGADVANVCNEAALIAARHL---SDSINQKHFEQAIERVIGGLEKKTQVL 563
SGAD+ N+C EAAL+A + + ++ Q+HF ++++ V L K L
Sbjct: 688 SGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTVKPSLSCKDLAL 737
Score = 139 bits (351), Expect = 8e-33
Identities = 85/230 (36%), Positives = 124/230 (53%), Gaps = 13/230 (5%)
Query: 310 VAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVP 368
+ G EA + E + L+ P+ LG +P+G +L GPPG GKT L +A A EA
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261
Query: 369 FITVSGSEFLEMFVGVGPARVRDLFALARKNA---PCILFIDEIDAVGRKRGRGNFGGQS 425
+ VS G VR +F AR+ A P +LF+DE+DA+ +RG ++
Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQRG-----SRA 316
Query: 426 EQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRAS 485
+ + Q+L +DG + VV++ TNRPD LDPAL RPGRFDR++ IG P +K R
Sbjct: 317 PESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKE 376
Query: 486 IFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARH 535
I +V + + S ++ LA +T G+ GAD+ +C EAA+ A H
Sbjct: 377 ILQVITSKMPISSHVD----LGLLAEMTVGYVGADLTALCREAAMHALLH 422
>gi|4505725 peroxin1 [Homo sapiens]
Length = 1283
Score = 152 bits (385), Expect = 9e-37
Identities = 89/233 (38%), Positives = 128/233 (54%), Gaps = 14/233 (6%)
Query: 304 DVKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDLGAKIP----KGAILTGPPGTGKTLLAK 359
D+ + + G E + +M+ + P +Y +L A +P G +L GPPGTGKTLLA
Sbjct: 836 DLGWDKIGGLHEVRQILMDTIQL---PAKYPELFANLPIRQRTGILLYGPPGTGKTLLAG 892
Query: 360 ATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRG 419
A E+ + FI+V G E L ++G VRD+F A+ PCILF DE +++ +RG
Sbjct: 893 VIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHD 952
Query: 420 NFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPD 479
N G + +NQLL ++DG V +LA T+RPD++DPALLRPGR D+ ++ PPD
Sbjct: 953 NTG---VTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPD 1009
Query: 480 IKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIA 532
R I V L L D + +AS+T F+GAD+ + A L A
Sbjct: 1010 QVSRLEILNV----LSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEA 1058
>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
Length = 415
Score = 151 bits (381), Expect = 3e-36
Identities = 88/250 (35%), Positives = 137/250 (54%), Gaps = 21/250 (8%)
Query: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365
+ + G + EI E + L +P+ Y+++G K PKG IL GPPGT
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
Query: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425
F+ V GSE ++ ++G GP VR +F +A ++AP I+F DEI+A+G KR N GG+
Sbjct: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
Query: 426 EQENTL--NQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
E + T+ +LL ++ GF++ +V ++ T + + LDP L+RPGR D++I PD K +
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
Query: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
IF++H + TL D L FSGAD+ +C EA L+A R +
Sbjct: 337 KHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNE 392
Query: 544 HFEQAIERVI 553
F+++IE V+
Sbjct: 393 DFKKSIESVL 402
>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
Length = 415
Score = 151 bits (381), Expect = 3e-36
Identities = 88/250 (35%), Positives = 137/250 (54%), Gaps = 21/250 (8%)
Query: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365
+ + G + EI E + L +P+ Y+++G K PKG IL GPPGT
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
Query: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425
F+ V GSE ++ ++G GP VR +F +A ++AP I+F DEI+A+G KR N GG+
Sbjct: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
Query: 426 EQENTL--NQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
E + T+ +LL ++ GF++ +V ++ T + + LDP L+RPGR D++I PD K +
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
Query: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
IF++H + TL D L FSGAD+ +C EA L+A R +
Sbjct: 337 KHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNE 392
Query: 544 HFEQAIERVI 553
F+++IE V+
Sbjct: 393 DFKKSIESVL 402
>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
sapiens]
Length = 415
Score = 151 bits (381), Expect = 3e-36
Identities = 88/250 (35%), Positives = 137/250 (54%), Gaps = 21/250 (8%)
Query: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365
+ + G + EI E + L +P+ Y+++G K PKG IL GPPGT
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
Query: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425
F+ V GSE ++ ++G GP VR +F +A ++AP I+F DEI+A+G KR N GG+
Sbjct: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
Query: 426 EQENTL--NQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483
E + T+ +LL ++ GF++ +V ++ T + + LDP L+RPGR D++I PD K +
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
Query: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543
IF++H + TL D L FSGAD+ +C EA L+A R +
Sbjct: 337 KHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNE 392
Query: 544 HFEQAIERVI 553
F+++IE V+
Sbjct: 393 DFKKSIESVL 402
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 141 bits (355), Expect = 3e-33
Identities = 99/290 (34%), Positives = 146/290 (50%), Gaps = 36/290 (12%)
Query: 291 VGETTAKVLKDEID--VKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILT 347
+G + A V ++D V+F V G + E V F L P+ ++ + P+G +
Sbjct: 407 IGASLADVDPMQLDSSVRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQPPRGCLFY 466
Query: 348 GPPGTGKTLLAKATA-----GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPC 402
GPPGTGKTL+A+A A G+ V F G++ L +VG ++R LF A + P
Sbjct: 467 GPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFDQAYQMRPS 526
Query: 403 ILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPA 462
I+F DEID + R + ++ LL MDG ++ +V++ TNR D +DPA
Sbjct: 527 IIFFDEIDGLAPVRSSRQ---DQIHSSIVSTLLALMDGLDSRGEIVVIGATNRLDSIDPA 583
Query: 463 LLRPGRFDRQIFIGPPDIKGRASIFKVHLR---PLKLDSTLEKDKLARKLASLTPGFSGA 519
L RPGRFDR+ PD + R I K+H R P LD+ LE +LA G+ GA
Sbjct: 584 LRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLE------ELAENCVGYCGA 637
Query: 520 DVANVCNEAALIAARH----------------LSDSINQKHFEQAIERVI 553
D+ ++C EAAL A R S +I+ K FE A++++I
Sbjct: 638 DIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMI 687
>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 140 bits (353), Expect = 5e-33
Identities = 91/240 (37%), Positives = 134/240 (55%), Gaps = 21/240 (8%)
Query: 305 VKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDL--GAKIP-KGAILTGPPGTGKTLLAKAT 361
+ + D+A EEAK + E V P D G + P KG ++ GPPGTGKT+LAKA
Sbjct: 205 IHWDDIADLEEAKKLLREAVVL---PMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAV 261
Query: 362 AGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNF 421
A E F VS S + G VR LF +AR AP +FIDEID++ +RG +
Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSD- 320
Query: 422 GGQSEQENTLNQLLVEMDGF-------NTTTNVVILAGTNRPDILDPALLRPGRFDRQIF 474
++LL++MDG + + V++LA TN P +D AL R R +++I+
Sbjct: 321 -EHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIY 377
Query: 475 IGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAAR 534
I P KGRA + K++LR ++LD ++ + +A K+ G+SGAD+ NVC +A+L+A R
Sbjct: 378 IPLPTAKGRAELLKINLREVELDPDIQLEDIAEKI----EGYSGADITNVCRDASLMAMR 433
>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
Length = 490
Score = 140 bits (353), Expect = 5e-33
Identities = 91/240 (37%), Positives = 134/240 (55%), Gaps = 21/240 (8%)
Query: 305 VKFKDVAGCEEAKLEIMEFVNFLKNPKQYQDL--GAKIP-KGAILTGPPGTGKTLLAKAT 361
+ + D+A EEAK + E V P D G + P KG ++ GPPGTGKT+LAKA
Sbjct: 205 IHWDDIADLEEAKKLLREAVVL---PMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAV 261
Query: 362 AGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNF 421
A E F VS S + G VR LF +AR AP +FIDEID++ +RG +
Sbjct: 262 ATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSD- 320
Query: 422 GGQSEQENTLNQLLVEMDGF-------NTTTNVVILAGTNRPDILDPALLRPGRFDRQIF 474
++LL++MDG + + V++LA TN P +D AL R R +++I+
Sbjct: 321 -EHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIY 377
Query: 475 IGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAAR 534
I P KGRA + K++LR ++LD ++ + +A K+ G+SGAD+ NVC +A+L+A R
Sbjct: 378 IPLPTAKGRAELLKINLREVELDPDIQLEDIAEKI----EGYSGADITNVCRDASLMAMR 433
>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
Length = 491
Score = 134 bits (336), Expect = 4e-31
Identities = 90/246 (36%), Positives = 135/246 (54%), Gaps = 19/246 (7%)
Query: 298 VLKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIP-KGAILTGPPGTGKT 355
++ +V++ D+A EAK + E V + P+ ++ G + P KG ++ GPPGTGKT
Sbjct: 199 IISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKT 256
Query: 356 LLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRK 415
LLAKA A E F VS S + G VR LF +AR +P +FIDEID++ +
Sbjct: 257 LLAKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSR 316
Query: 416 RGRGNFGGQSEQENTLNQLLVEMDGFNTTTN-------VVILAGTNRPDILDPALLRPGR 468
RG S + +LLV+MDG T+ V++LA TN P +D AL R R
Sbjct: 317 RGTSEEHEASRRVKA--ELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--R 372
Query: 469 FDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEA 528
+++I+I P KGR + ++ LR L+L ++ +A + G+SGAD+ NVC +A
Sbjct: 373 LEKRIYIPLPSAKGREELLRISLRELELADDVDLASIAENM----EGYSGADITNVCRDA 428
Query: 529 ALIAAR 534
+L+A R
Sbjct: 429 SLMAMR 434
>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
Length = 1458
Score = 133 bits (335), Expect = 6e-31
Identities = 90/252 (35%), Positives = 126/252 (50%), Gaps = 14/252 (5%)
Query: 291 VGETTAKVLKDEID--VKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILT 347
VG + A V ID V+F + G + E V F L P+ ++ + P+G +
Sbjct: 381 VGASLADVDPMNIDKSVRFDSIGGLSHHIHALKEMVVFPLLYPEIFEKFKIQPPRGCLFY 440
Query: 348 GPPGTGKTLLAKATA-----GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPC 402
GPPGTGKTL+A+A A G+ V F G++ L +VG ++R LF A P
Sbjct: 441 GPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESERQLRLLFDQAYLMRPS 500
Query: 403 ILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPA 462
I+F DEID + R + ++ LL MDG + +V++ TNR D +DPA
Sbjct: 501 IIFFDEIDGLAPVRSSRQ---DQIHSSIVSTLLALMDGLDNRGEIVVIGATNRLDSIDPA 557
Query: 463 LLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVA 522
L RPGRFDR+ PD K R I ++H R + D +LA G+ GAD+
Sbjct: 558 LRRPGRFDREFLFNLPDQKARKHILQIHTRDW---NPKLSDAFLGELAEKCVGYCGADIK 614
Query: 523 NVCNEAALIAAR 534
+C EAALIA R
Sbjct: 615 ALCTEAALIALR 626
>gi|40806170 spastin isoform 2 [Homo sapiens]
Length = 584
Score = 131 bits (329), Expect = 3e-30
Identities = 93/270 (34%), Positives = 143/270 (52%), Gaps = 17/270 (6%)
Query: 275 PAGIGRTGRGMGGLFSVGETTAKVLKDEI-----DVKFKDVAGCEEAKLEIMEFVNFLKN 329
P R + + +V A ++ +EI VKF D+AG + AK + E V L +
Sbjct: 272 PTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIV-ILPS 330
Query: 330 PKQYQDLGAKIP-KGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPAR 388
+ G + P +G +L GPPG GKT+LAKA A E+N F +S + +VG G
Sbjct: 331 LRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKL 390
Query: 389 VRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTT--TN 446
VR LFA+AR+ P I+FIDE+D++ +R G + L+E DG +
Sbjct: 391 VRALFAVARELQPSIIFIDEVDSLLCERREGE---HDASRRLKTEFLIEFDGVQSAGDDR 447
Query: 447 VVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLA 506
V+++ TNRP LD A+LR RF +++++ P+ + R + K L K S L + +LA
Sbjct: 448 VLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEETRLLLLKNLL--CKQGSPLTQKELA 503
Query: 507 RKLASLTPGFSGADVANVCNEAALIAARHL 536
+LA +T G+SG+D+ + +AAL R L
Sbjct: 504 -QLARMTDGYSGSDLTALAKDAALGPIREL 532
>gi|11875211 spastin isoform 1 [Homo sapiens]
Length = 616
Score = 131 bits (329), Expect = 3e-30
Identities = 93/270 (34%), Positives = 143/270 (52%), Gaps = 17/270 (6%)
Query: 275 PAGIGRTGRGMGGLFSVGETTAKVLKDEI-----DVKFKDVAGCEEAKLEIMEFVNFLKN 329
P R + + +V A ++ +EI VKF D+AG + AK + E V L +
Sbjct: 304 PTTATRKKKDLKNFRNVDSNLANLIMNEIVDNGTAVKFDDIAGQDLAKQALQEIV-ILPS 362
Query: 330 PKQYQDLGAKIP-KGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPAR 388
+ G + P +G +L GPPG GKT+LAKA A E+N F +S + +VG G
Sbjct: 363 LRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKL 422
Query: 389 VRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQSEQENTLNQLLVEMDGFNTT--TN 446
VR LFA+AR+ P I+FIDE+D++ +R G + L+E DG +
Sbjct: 423 VRALFAVARELQPSIIFIDEVDSLLCERREGE---HDASRRLKTEFLIEFDGVQSAGDDR 479
Query: 447 VVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLA 506
V+++ TNRP LD A+LR RF +++++ P+ + R + K L K S L + +LA
Sbjct: 480 VLVMGATNRPQELDEAVLR--RFIKRVYVSLPNEETRLLLLKNLL--CKQGSPLTQKELA 535
Query: 507 RKLASLTPGFSGADVANVCNEAALIAARHL 536
+LA +T G+SG+D+ + +AAL R L
Sbjct: 536 -QLARMTDGYSGSDLTALAKDAALGPIREL 564
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,836,478
Number of Sequences: 37866
Number of extensions: 1536797
Number of successful extensions: 9535
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 99
Number of HSP's successfully gapped in prelim test: 30
Number of HSP's that attempted gapping in prelim test: 8716
Number of HSP's gapped (non-prelim): 564
length of query: 797
length of database: 18,247,518
effective HSP length: 110
effective length of query: 687
effective length of database: 14,082,258
effective search space: 9674511246
effective search space used: 9674511246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.