BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] (1142 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 2444 0.0 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 761 0.0 gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] 739 0.0 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 686 0.0 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 652 0.0 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 652 0.0 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 652 0.0 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 635 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 634 0.0 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 625 e-179 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 624 e-178 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 624 e-178 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 624 e-178 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 622 e-178 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 622 e-178 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 622 e-178 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 615 e-176 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 615 e-176 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 614 e-175 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 612 e-175 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 612 e-175 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 612 e-175 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 610 e-174 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 605 e-173 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 599 e-171 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 596 e-170 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 593 e-169 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 592 e-169 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 592 e-169 gi|48762934 alpha 2 type I collagen [Homo sapiens] 570 e-162 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 2444 bits (6333), Expect = 0.0 Identities = 1142/1142 (100%), Positives = 1142/1142 (100%) Query: 1 MRLTGPWKLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLG 60 MRLTGPWKLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLG Sbjct: 1 MRLTGPWKLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLG 60 Query: 61 DSFSLRRAFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLW 120 DSFSLRRAFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLW Sbjct: 61 DSFSLRRAFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWFLW 120 Query: 121 QVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQS 180 QVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQS Sbjct: 121 QVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQS 180 Query: 181 QVISLYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSANLIAQE 240 QVISLYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSANLIAQE Sbjct: 181 QVISLYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSANLIAQE 240 Query: 241 TCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAP 300 TCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAP Sbjct: 241 TCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAP 300 Query: 301 GSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGEN 360 GSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGEN Sbjct: 301 GSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGEN 360 Query: 361 GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP 420 GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP Sbjct: 361 GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP 420 Query: 421 GPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKG 480 GPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKG Sbjct: 421 GPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKG 480 Query: 481 EPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG 540 EPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG Sbjct: 481 EPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG 540 Query: 541 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPG 600 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPG Sbjct: 541 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPG 600 Query: 601 PRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 PRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN Sbjct: 601 PRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 Query: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG Sbjct: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 Query: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG Sbjct: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY 840 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY Sbjct: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY 840 Query: 841 PGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGV 900 PGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGV Sbjct: 841 PGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGV 900 Query: 901 PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD 960 PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD Sbjct: 901 PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD 960 Query: 961 RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK Sbjct: 961 RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK Sbjct: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 Query: 1081 GERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQRTG 1140 GERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQRTG Sbjct: 1081 GERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQRTG 1140 Query: 1141 GN 1142 GN Sbjct: 1141 GN 1142 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 761 bits (1966), Expect = 0.0 Identities = 493/1279 (38%), Positives = 613/1279 (47%), Gaps = 243/1279 (18%) Query: 34 CPILRIEGHQLTYDNINKLEVSGFDLGDSFSLRRAFCESDK----TCFKLGSALLIRDTI 89 CP +R+EG + + N E++GFDL D FS++ + + + ++GS +++ T Sbjct: 223 CPSVRVEGDRFKHTNGGTKEITGFDLMDLFSVKEILGKRENGAQSSYVRMGSFPVVQSTE 282 Query: 90 KIFPKGLPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNIPQISIVVDGGKKVVEFMFQAT 149 +FP+GLP+EY+ FR R+ ++KE W++WQV++Q +IPQ+SI +DG K VE+ Sbjct: 283 DVFPQGLPDEYAFVTTFRFRKTSRKEDWYIWQVIDQYSIPQVSIRLDGENKAVEYNAVGA 342 Query: 150 EGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMDCNLIARRQTDEKDTVDFHGRT 209 D + +FR + LFDR WHK+ +SIQ+Q +SL++DC L+ +E++ +D G+T Sbjct: 343 MKDAVRVVFRGSRVNDLFDRDWHKMALSIQAQNVSLHIDCALVQTLPIEERENIDIQGKT 402 Query: 210 VIATRASDGKPVDIELHQLKIYCSANLIAQETCCEISDTKCPEQDGFGNIASSWVTAHAS 269 VI R D P+D +L ++ IYC + ETCC+I C + Sbjct: 403 VIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVT------VVTEPPPPPP 456 Query: 270 KMSSYLPAKQEL----KDQCQC-IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFP 324 P +++ C C KGE G+ G G PG KG + G G GAPG Sbjct: 457 PQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKG---DIGAIGPVGAPGPK 513 Query: 325 GQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPP 384 G+KG+ G G G+ GEKGE+G G P G +G G++G+ G G PG GE G GP Sbjct: 514 GEKGDVGI-GPFGQ-GEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQ 571 Query: 385 GPPALP------GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTL 438 GPP LP G+ G+QG +G G G++G RG G PGKPG G G PG G+ Sbjct: 572 GPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGV---- 627 Query: 439 GGYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSV-------------GPKGQKGEPG 483 AG G KGD G G PG PGSV GP+G +G PG Sbjct: 628 ---------------AGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG 672 Query: 484 EPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVG 543 P +G G G G G QG++G+ GD GPPG+ G GL+G G G GP GP G G Sbjct: 673 PPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPG 732 Query: 544 LPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGK-SLPGEPGLD---GNPG 597 LPGE G PGK G G G PG G GPPG PG KGE G G+ LPG+PGL G G Sbjct: 733 LPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQG 792 Query: 598 APGPRGPKGERGLPGVHGSPGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPG 650 G G KGE GLPG G PG G +G +G+PG G +G GE G GP GLPG Sbjct: 793 LAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPG 852 Query: 651 ----------LPGTPGTPGNDGVPGRDGKPGLPGPPGD-----PIALP-LLGDIGAL-LK 693 +PG G G G PG G+PGL G PG+ P P G GA Sbjct: 853 TTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAP 912 Query: 694 NFCGNCQA----------------SVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPP 737 GN A PGL+ G++G GE G G +GPRG P Sbjct: 913 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 972 Query: 738 GIPGREGP--KGSKGE---RGYPGIPGE-----------------------KGDEGLQGI 769 G PG GP KG GE RG PG+PG KGD G GI Sbjct: 973 GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGI 1032 Query: 770 PGIPGA-----------PGPTGP------PGLMGRTGHPGP------TGAKGEKGSDGPP 806 PG PG+ PGP+GP PG G G PGP GA G G GPP Sbjct: 1033 PGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPP 1092 Query: 807 GKPG---------------------PPGPPGIP----------FNERNGMSSLYKIKGGV 835 GKPG PPGPPG+P + G KG Sbjct: 1093 GKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEA 1152 Query: 836 NVPSYPGPPGPPGP---------------KGDPGPVGEPGAMGLPGLEGFPGVKGDRGPA 880 P PGPPG GP KGD G G PG MG PG G PG G G A Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAA 1212 Query: 881 GPPGIAGMSGKPGAPGP------PGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934 GPPGI G GK G PGP PG+PGE G+ G G G PG G +G+PG+ G +G Sbjct: 1213 GPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGAR 1272 Query: 935 GAQGIMGKPGDR---GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSM 991 G G G GD GP+GE G G+PG G G+ G G TG +G GP GPPG GS Sbjct: 1273 GPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 GSPG GP G+PG G + S + FL P Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGS-----------------PGLPGFLGPRGPPGEP---- 1371 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQ---KGERGEP-GIGLPGSPGLPG----TSALG 1103 G G PGK+G+PG PG+PG +G RG KG++G P G G PG PG+PG T +G Sbjct: 1372 --GEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMG 1429 Query: 1104 LPGSPGAPGPQGPPGPSGR 1122 G PG GP GPPGP G+ Sbjct: 1430 PQGLPGENGPVGPPGPPGQ 1448 Score = 756 bits (1951), Expect = 0.0 Identities = 447/1041 (42%), Positives = 531/1041 (51%), Gaps = 201/1041 (19%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG---EKGEQGEK 348 G G PG G G+KG +GE GE GL G PG PG G+QG G G G EKG+ G Sbjct: 581 GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPA 640 Query: 349 GDPALAG-------LNGENGLKGDLGPHGPPGPKGEKGDTGPPG---------------- 385 G P + G L GE G G G G PGP G +G GP G Sbjct: 641 GPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGD 700 Query: 386 --PPALPGSLGIQGPQGPPGKEG------------------QRGRRGKTGPPGKPGPPGP 425 PP +PG LG+QGP GPPG G + G G TGPPGK GP GP Sbjct: 701 MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP 760 Query: 426 PGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGE 481 PGPPG +G G G K + E G G G+KGE GLPG PG G +G+KG+ Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820 Query: 482 PGE----------------------------------------PFTKGEKGDRGEPGVIG 501 GE P +G KG++G+PG+ G Sbjct: 821 QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880 Query: 502 SQGVKGEPGDPGPPGLIGSPGLKGQQGS---------------AGSMGPRGPPGDVGLPG 546 G++G PG+ GP G G PG KGQ+G+ G+ GP GPPG VG PG Sbjct: 881 EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPG 940 Query: 547 EHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP 601 G PGK G +GEKG G G +GP G PG G GPPGK GEPGL G+PG PGP Sbjct: 941 LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 1000 Query: 602 RGPK--------------------GERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPG 641 G K G+RG PG+ GSPG G GIG+ G G GP G+ G Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 1060 Query: 642 IQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLL--GDIGALLKNFCGNC 699 G RGLPG PG G G DG PG PG GPPG P LL GDI L K+ C +C Sbjct: 1061 SPGSRGLPGFPGPQGPAGRDGAPGN---PGERGPPGKPGLSSLLSPGDINLLAKDVCNDC 1117 Query: 700 QAS---VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPG 756 +PGL KG++G G+PG+ + +KG+ GP G PG PG GP+GS+GERG G Sbjct: 1118 PPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADG 1177 Query: 757 IPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPG 816 G+KGD+G G+PG G PG GPPG G G GP G +G G +GPPG GP G PG Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 817 IPFNE----RNGMSSLYKIKGGVNVPSYPGPPG---PPGPKGD------PGPVGEPGAMG 863 IP E R+G G P PGP G PPG KG PGP GE GAMG Sbjct: 1238 IPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMG 1297 Query: 864 LPGLEGFPGVKGD---------RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIG 914 LPG EG PG GD +GP GPPG G G PG PGP G PG+ G +G G G Sbjct: 1298 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPG 1357 Query: 915 FPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRG---SQGERGKPG 971 PG GP G PG G+ G+PG +G+ GKPG+ G KGERGD GI GD+G +G+ G PG Sbjct: 1358 LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPG 1417 Query: 972 LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFE 1031 + G KG G MGP G G G G GPPG PG PG+ ++ S E +++ I +E+ + E Sbjct: 1418 IPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE 1477 Query: 1032 ERMAVFLSQLKLPAAMLAAQAY-GRPGPPGKDGLP---GPPGDP---------------G 1072 R+A L+Q+ PA M ++Q G PGPPGKDGLP GP G+P G Sbjct: 1478 TRLAYLLAQMP-PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIG 1536 Query: 1073 PQGYRGQKGERGEPGIGL---------PGSPGLPGTSALGLPGSPGA---------PGPQ 1114 P+G RG KG+ G PG+GL PG PG PG + GLPG PG PG Sbjct: 1537 PKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLP 1596 Query: 1115 GPPGPSGRCNPEDCLYPVSHA 1135 GPPGP G+C+P C Y S A Sbjct: 1597 GPPGPPGQCDPSQCAYFASLA 1617 Score = 611 bits (1576), Expect = e-174 Identities = 406/1073 (37%), Positives = 476/1073 (44%), Gaps = 288/1073 (26%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGE------------NGLHGAPGFPGQKGEQGFEGSKGE 338 KG GLPG PG G KG +GEPGE G G PG PG G G G +GE Sbjct: 532 KGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE 591 Query: 339 TGEKGEQGEKGDPALAGLNG---ENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGS--- 392 GEKG +GEKG+ L G G + G +G GP G GP+GEKGD GP GPP +PGS Sbjct: 592 RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQ 651 Query: 393 ----------------------------LGIQGPQGPPGKEGQRGRRGKTGPPG------ 418 +G +G GPPG +G RG++G GPPG Sbjct: 652 QEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG 711 Query: 419 ------KPGPPGPPGPPGIQGIHQTLG-----------GYYNKDNKGNDEHEAG--GLKG 459 PG PGPPGP G G+ +G G KD G G G Sbjct: 712 LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIG 519 ++GE GLPG PG G G++G G P GEKG+ G PG G GV+GE GD G G +G Sbjct: 772 ERGEDGLPGKPGLRGEIGEQGLAGRP---GEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828 Query: 520 SPGLKGQQGSAGSMGPRGPPGDVGLPGEHGI-------PGKQGIKGEKGDPG-----GII 567 PGLKG +G G GP GPPG LPG + PG+QG KGEKGDPG G+ Sbjct: 829 LPGLKGDRGEKGEAGPAGPPG---LPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 885 Query: 568 GPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPG------PRGPKGERGLPGVHGSP 617 G PG GP+G GPPG + G PG GNPGAPG P GP G G PG+ G+P Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTP 945 Query: 618 GDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN--DGVPGRDGKPGLPGP 675 G G +G GA G G PG GPRG PG PG PG PG DG PG G PGLPGP Sbjct: 946 GKDGERG-----EKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 1000 Query: 676 PGDPIAL-PLLGDIGALLKNFCGNCQASVPGLKSNKGEEGG-----AGEPGKYDSMARKG 729 G A + G L C PG+ + G G AG PG KG Sbjct: 1001 LGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKG 1060 Query: 730 DIGPRGPPGIPGREGPKG------SKGERG------------------------------ 753 G RG PG PG +GP G + GERG Sbjct: 1061 SPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120 Query: 754 ---YPGIPGEKGDEGLQGIPG---IPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPG 807 PG+PG KGD+G+ G PG G G GPPGL G G GP G++GE+G+DG G Sbjct: 1121 PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 1180 Query: 808 KPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPG---------PPGPKGDPGPVGE 858 + G G PG+P G + P PGPPG PPG +G PG G Sbjct: 1181 QKGDQGHPGVP--------------GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226 Query: 859 PGAMGLPGLEGFPGVKGDRG---PAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGF 915 PG G GL G PG +G G GPPG G +G+PG PGP G G PG +G GD G Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGA 1286 Query: 916 PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD---------------QGIPGD 960 PGP G SG G+ G++G+PG G G G +GP+G RG G PG Sbjct: 1287 PGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQ 1346 Query: 961 RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 +GS+GE G PGL G +GP GPPG G G PG +G PG PG PG + IK Sbjct: 1347 KGSKGENGSPGLPGF---LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD-PGIK- 1401 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 G GPPG G PG PG PG +G+ G Sbjct: 1402 ---------------------------------GDKGPPGGKGQPGDPGIPGHKGHTGLM 1428 Query: 1081 GERGEPG----IGLPGSPGLPG-------------------------------------- 1098 G +G PG +G PG PG PG Sbjct: 1429 GPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP 1488 Query: 1099 ----TSALGLPGSPGAPG---------PQGPPGPSGRCNPEDCLYPVSHAHQR 1138 S+ G PG PG PG P G PG G+ E P+ +R Sbjct: 1489 PAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541 Score = 475 bits (1223), Expect = e-134 Identities = 301/712 (42%), Positives = 339/712 (47%), Gaps = 139/712 (19%) Query: 291 KGEAGLPGAPG------SPGQKGH-----KGEPGENGLHGAPGFPGQKGEQGFEGS--KG 337 KG AG G+PG PG G KG+ GE GL G+PG PG G + G Sbjct: 954 KGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGS 1013 Query: 338 ETGEKGEQGEKGDPALAGLNGENGLKGD--LGPHGPPGPKGEKGDTGPPGPPALPGSLGI 395 E G Q KGD G+ G G +GD +G GPPGP G GD G PG LP G Sbjct: 1014 ENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP---GF 1070 Query: 396 QGPQGPPGKEGQRGRRGKTGPPGKPG---------------------PPGPPGPPGIQGI 434 GPQGP G++G G G+ GPPGKPG PPGPPG PG+ G Sbjct: 1071 PGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGF 1130 Query: 435 HQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDR 494 G +G + G KG+ G GLPG PG GP+G +GE G G+KGD+ Sbjct: 1131 KGDKGVPGKPGREGTE-----GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 1185 Query: 495 GEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQ 554 G PGV G G G PG PG G+ G+ G G QGS G GP GP G GLPG G GK+ Sbjct: 1186 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKE 1245 Query: 555 GIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 G G+ G PG G G PGLPGP+G GPPG G G+ GAPGPRG G GLPG Sbjct: 1246 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK-----GHTGDSGAPGPRGESGAMGLPG 1300 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 G PG G G G G QGP G PG G G PG PG GTPG G G +G PGL Sbjct: 1301 QEGLPGKDG--DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGL 1358 Query: 673 P------GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMA 726 P GPPG+P G K G+EG G+PG+ Sbjct: 1359 PGFLGPRGPPGEP-------------------------GEKGVPGKEGVPGKPGE----- 1388 Query: 727 RKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMG 786 G G RG PGI G +GP G KG+ G PGIPG KG GL G G+PG GP GPPG G Sbjct: 1389 -PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPG 1447 Query: 787 RTGHPGPTGAKGE--------------------------------KGSDGPPGKPGPPGP 814 + G PG G K S G PG PGPPG Sbjct: 1448 QPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGK 1507 Query: 815 PGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVK 874 G+P G + P PG G GP G GP GE GA G PG PGV Sbjct: 1508 DGLPGR-----------AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA---PGV- 1552 Query: 875 GDRGPAGPPGIAGMSGKPG--APGPPGVPGEPGERGPVGDIGFPGPEGPSGK 924 G RG GPPGI G G+PG G PG+PG GE GP G G PGP GP G+ Sbjct: 1553 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Score = 449 bits (1154), Expect = e-126 Identities = 280/698 (40%), Positives = 331/698 (47%), Gaps = 139/698 (19%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSK--GETGEKGEQGEKG 349 G G PGAPG PG G KG+ GE GL G+PG PG G + G E G Q KG Sbjct: 967 GPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKG 1025 Query: 350 DPALAGLNGENGLKGD--LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 D G+ G G +GD +G GPPGP G GD G PG LPG GPQGP G++G Sbjct: 1026 DRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG---FPGPQGPAGRDGA 1082 Query: 408 RGRRGKTGPPGKPG---------------------PPGPPGPPGIQGIHQTLGGYYNKDN 446 G G+ GPPGKPG PPGPPG PG+ G G Sbjct: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGR 1142 Query: 447 KGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVK 506 +G + G KG+ G GLPG PG GP+G +GE G G+KGD+G PGV G G Sbjct: 1143 EGTE-----GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPP 1197 Query: 507 GEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-- 564 G PG PG G+ G+ G G QGS G GP GP G GLPG G GK+G G+ G PG Sbjct: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP 1257 Query: 565 GIIGPPGLPGPKGEAGPPG-------------------KSLPGE---PGLDGNPGAPGPR 602 G G PGLPGP+G GPPG LPG+ PG DG+ G GP+ Sbjct: 1258 GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQ 1317 Query: 603 GPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQG---PRGLPGLPGTPGTP 658 GP+G RG PG +GSPG G G G PG+ G++G G PG+ G PRG PG PG G P Sbjct: 1318 GPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVP 1377 Query: 659 GNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G +GVPG+ G+PG G GDP G+K +KG GG G+ Sbjct: 1378 GKEGVPGKPGEPGFKGERGDP-------------------------GIKGDKGPPGGKGQ 1412 Query: 719 PGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD--------------- 763 PG KG G GP G+PG GP G G G PG PG +G+ Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 1472 Query: 764 --------------------EGLQGIPGIPGAPGPTGPPGL---MGRTGHPGPTGAKGEK 800 + QG PG PG PG G PG MG G PG G +G Sbjct: 1473 GKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPS 1532 Query: 801 GSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD-----PGP 855 G GP G+ G G PG P G+ ++G + P PG PG PG D PGP Sbjct: 1533 GPIGPKGERGAKGDPGAP-----GVG----LRGEMGPPGIPGQPGEPGYAKDGLPGIPGP 1583 Query: 856 VGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPG 893 GE G G PGL G PG G P+ A ++ +PG Sbjct: 1584 QGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1621 Score = 441 bits (1134), Expect = e-123 Identities = 288/732 (39%), Positives = 339/732 (46%), Gaps = 124/732 (16%) Query: 492 GDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAG----SMGPRGPPGDVGLPGE 547 G++GE GV G G+ G GD G G +G+PG KG++G G G +G G +GLPG Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGP 540 Query: 548 HGIPGKQGIKGEKGDPGGIIGPPGLPGP---KGEAGPPGKSLP----GEPGLDGNPGAPG 600 PG+ G KG +G+PG + G PGLPG +G GPPG P G PGL G G G Sbjct: 541 ---PGRDGSKGMRGEPGEL-GEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596 Query: 601 PRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGT----PG 656 RG KGERGL G G PGD G QG PG +G GP GE G GP G PG+PG+ G Sbjct: 597 TRGEKGERGLDGFPGKPGDTGQQGR--PGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEG 654 Query: 657 TPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA 716 G G PG G G PGPPG + G EG Sbjct: 655 LKGEQGAPGPRGHQGAPGPPG----------------------------ARGPIGPEGRD 686 Query: 717 GEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP 776 G PG +KGD+GP G PG+ G +GP G G G PG G G G G PG PG P Sbjct: 687 GPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPP 746 Query: 777 GPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVN 836 GPTGPPG G G PGP G KGE G G G PG PG G G L G Sbjct: 747 GPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRG-----EIGEQGLAGRPGEKG 801 Query: 837 VPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMS------- 889 PG PG PG +G+ G GE G +GLPGL+G G KG+ GPAGPPG+ G + Sbjct: 802 EAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHP 861 Query: 890 ------------GKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQ 937 G PG PG PG+ G PGE GP G G PG +G G G G G PGA Sbjct: 862 RMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAP 921 Query: 938 GIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPG-- 995 G +G PG GP G G G+ G G GERG+ G G +G+ GP+GP G+ G+ G PG Sbjct: 922 GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPP 981 Query: 996 ---HQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAA------ 1046 G PG G PG+P + K E + + + +P + Sbjct: 982 GKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGD 1041 Query: 1047 --MLAAQAYGRPGPPGKDGLPGP---PGDPGPQGYRGQKG------ERGEPGI------- 1088 + A G GPPG G PG PG PGPQG G+ G ERG PG Sbjct: 1042 PGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLL 1101 Query: 1089 ------------------GLPGSPGLPGTSA-LGLPGSPG---APGPQGPPGPSGRCNPE 1126 G PG PGLPG G+PG PG G +G GP G P Sbjct: 1102 SPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPP 1161 Query: 1127 DCLYPVSHAHQR 1138 P +R Sbjct: 1162 GIAGPQGSQGER 1173 Score = 428 bits (1100), Expect = e-119 Identities = 264/656 (40%), Positives = 316/656 (48%), Gaps = 139/656 (21%) Query: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 P G AG PG G PG KG PG GL PGFPG +G G +G+ G GE+G G+ Sbjct: 1042 PGIGVAGPPGPSGPPGD---KGSPGSRGL---PGFPGPQGPAGRDGAPGNPGERGPPGKP 1095 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQR 408 G +L N L D+ PP GPPG P LPG G +G G PG+EG Sbjct: 1096 GLSSLLSPGDINLLAKDVCNDCPP---------GPPGLPGLPGFKGDKGVPGKPGREGTE 1146 Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG 468 G++G+ GPPG PGPPG GP G QG E A G G KG+ G PG Sbjct: 1147 GKKGEAGPPGLPGPPGIAGPQGSQG-----------------ERGADGEVGQKGDQGHPG 1189 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 PG +GP G G PG G G G PG+ GS G +G PG GP GL PG+ G++G Sbjct: 1190 VPGFMGPPGNPGPPG---ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGL---PGIPGEEG 1243 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPG 588 G G GPPG+ G GE G+PG +G +G G G G G PGP+GE+G G LPG Sbjct: 1244 KEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH-TGDSGAPGPRGESGAMG--LPG 1300 Query: 589 E---PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQ- 643 + PG DG+ G GP+GP+G RG PG +GSPG G G G PG+ G++G G PG+ Sbjct: 1301 QEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPG 1360 Query: 644 --GPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQA 701 GPRG PG PG G PG +GVPG+ G+PG G GD Sbjct: 1361 FLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGD----------------------- 1397 Query: 702 SVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEK 761 PG+K +KG GG G+PG KG G GP G+PG GP G G G PG PG + Sbjct: 1398 --PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLR 1455 Query: 762 GD-----------------------------------EGLQGIPGIPGAPGPTGPPGL-- 784 G+ + QG PG PG PG G PG Sbjct: 1456 GESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAG 1515 Query: 785 -MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP 843 MG G PG G +G G GP G+ G G PG P GV + GP Sbjct: 1516 PMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAP---------------GVGLRGEMGP 1560 Query: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPG 899 PG PG G+PG + GL G PG +G+ GPAG PG+ PG PGPPG Sbjct: 1561 PGIPGQPGEPGYAKD-------GLPGIPGPQGETGPAGHPGL------PGPPGPPG 1603 Score = 127 bits (319), Expect = 6e-29 Identities = 86/220 (39%), Positives = 104/220 (47%), Gaps = 46/220 (20%) Query: 290 NKGEAGLPGAPGSPGQKGHKGE---------PGENGLHGAPGFPGQKGEQGFEGSKGETG 340 +KG G G PG PG GHKG PGENG G PG PGQ GF G +GE+ Sbjct: 1403 DKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQ---PGFPGLRGESP 1459 Query: 341 E--------KGEQGEKGDPALAGLNGE------NGLKGDLGPHGPPGPKGEKGDTGPPGP 386 + E G++ + LA L + +G GP GPPG G G GP G Sbjct: 1460 SMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGE 1519 Query: 387 PALPGSLGIQGPQGPPGKEGQRGRRGKTGPP-----GKPGPPGPPGPPGIQGIHQTLGGY 441 P PG G++GP GP G +G+RG +G G P G+ GPPG PG PG G Sbjct: 1520 PGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG-------- 1571 Query: 442 YNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGE 481 Y KD G+ G +GETG G PG GP G G+ Sbjct: 1572 YAKDG-------LPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Score = 56.2 bits (134), Expect = 2e-07 Identities = 37/102 (36%), Positives = 44/102 (43%), Gaps = 20/102 (19%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P + L+ I KGE G G PG+PG G G G PG PGQ GE G+ Sbjct: 1523 PGQGGLEGPSGPIGPKGERGAKGDPGAPG-------VGLRGEMGPPGIPGQPGEPGY--- 1572 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGE 377 + G P + G GE G G G GPPGP G+ Sbjct: 1573 ----------AKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 >gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens] Length = 1604 Score = 739 bits (1908), Expect = 0.0 Identities = 531/1593 (33%), Positives = 679/1593 (42%), Gaps = 486/1593 (30%) Query: 5 GPWKLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDLGDSFS 64 G W L LW + F A+T CP + EG +L + + V+GF+L S Sbjct: 8 GLWLLGLWAT-FGHGANTGA--------QCPPSQQEGLKLEHSSSLPANVTGFNLIHRLS 58 Query: 65 LRRAFC------ESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWF 118 L + +LG+A + + T ++FP+GLPEE+++ ++++ ++ W+ Sbjct: 59 LMKTSAIKKIRNPKGPLILRLGAAPVTQPTRRVFPRGLPEEFALVLTLLLKKHTHQKTWY 118 Query: 119 LWQVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISI 178 L+QV + PQIS+ V+ ++ +E Q +GD ++ IF + LFD +WHKL +S+ Sbjct: 119 LFQVTDANGYPQISLEVNSQERSLELRAQGQDGDFVSCIF---PVPQLFDLRWHKLMLSV 175 Query: 179 QSQVISLYMDCNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSANLIA 238 +V S+++DC+ + + + + G + A GKPV +L Q+ IYC L+ Sbjct: 176 AGRVASVHVDCSSASSQPLGPRRPMRPVGHVFLGLDAEQGKPVSFDLQQVHIYCDPELVL 235 Query: 239 QETCCEISDTKCP---------------------------------EQDGFGNIASSWVT 265 +E CCEI CP E+ + + Sbjct: 236 EEGCCEILPAGCPPETSKARRDTQSNELIEINPQSEGKVYTRCFCLEEPQNSEVDAQLTG 295 Query: 266 AHASKMSSYLPAKQE-LKDQC-QCIPN----------KGEAGLPGAPGSPGQKGHKGEPG 313 + K QE D+C C+ G G G G PG G KGE G Sbjct: 296 RISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKG 355 Query: 314 ENG-----------LHGAPGFPGQKGEQGF---EGSKGETGEKGEQGEKGDPALAGLNGE 359 G L A G G+KGE G G G TGEKG++GEKGD + G+ G+ Sbjct: 356 ARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGK 415 Query: 360 NGLKGDLGPHGPPGPKGEKGD---------TGPPGPPALPG--SLGIQGPQGPP-GKEGQ 407 G G G GPKG+KGD G PGPP LPG +G+ G G P G G Sbjct: 416 PGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGP 475 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQG-----------IHQTLGGYYNKDNKGNDEHEAG- 455 +G +G +G PGK GP G PG PG++G + + + K + E G Sbjct: 476 KGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGD 535 Query: 456 -----------GLKGDKGET----------------------------GLPGFPGSVGPK 476 G+KG+KGE GLPG PG G Sbjct: 536 PVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVP 595 Query: 477 GQKGEPGEPFTKGEKGDRGEPGVIGSQGVK------------------------------ 506 G KGE G G G G PG +G G+K Sbjct: 596 GLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPS 655 Query: 507 GEPGDPGPPGL--------IGSPGLKGQQGSAGSMGPRGPPGDVGLP---GEHGIPGKQG 555 GE G+PGPPG G GLKGQ+G AG+ G G PG G P GE G+ G G Sbjct: 656 GEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAG 715 Query: 556 IKGEKGD------------------PG-------------------------GIIGPPGL 572 KGEKGD PG G+ GPPGL Sbjct: 716 PKGEKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGL 775 Query: 573 PGPKGEAGPPGKSL------PGEPGLDGNPGAPGPRGP------KGERGLPGVHGSPGDI 620 G +GE GPPG+ + PG PGL G G PGPRGP KG +G PGV G+ G + Sbjct: 776 KGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPV 835 Query: 621 GPQGI---GIPGRTGAQGPAG--------------------------------------- 638 GP G G PGR G QG G Sbjct: 836 GPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGL 895 Query: 639 ------EPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692 +PG QGP G+PG PG PG PG GVPG +G PG PG + +LP+ LL Sbjct: 896 WMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQH---LL 952 Query: 693 KNFCGNC---QASVPGLKSNKGEEGGAGEPG--KYDSMA--------------------- 726 K+ CG+C Q + PG KGE+G G PG D+ A Sbjct: 953 KSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEG 1012 Query: 727 ------------------RKGDIGP---RGPPGIPGREGPKGSKGERGYPGIPGEKGDEG 765 ++G+ GP RG PG PG GP G G G PG+PG +G+ G Sbjct: 1013 DPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERG 1072 Query: 766 LQGI---------PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGK-------- 808 L G+ PG PG PG TGPPGL G G G TG+ GEKG GPPG Sbjct: 1073 LTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPG 1132 Query: 809 ----------------------------PGPPGPPGIPFNERN-------GMSSLYKIKG 833 PGPPGPPG P + I+G Sbjct: 1133 PAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRG 1192 Query: 834 GVNVPSYPGPPGPPGPK------------------GDPGPVGEPGAMGLPGLE------G 869 +P PGPPGPPG + GDPGP G PG MG PG + G Sbjct: 1193 PSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPG 1252 Query: 870 FPGVKGDRGPAGPPGIAGM------------SGKPGAP---GPPGVPGEPG--------- 905 PG KGD G GPPG G G+PG P GPPG PG+PG Sbjct: 1253 LPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGL 1312 Query: 906 --------ERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGI 957 ERG G G PGP G G PG G DG G +G GK G GP G +GD G Sbjct: 1313 KGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGA 1372 Query: 958 PGDRGSQGERGK---PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIP---AD 1011 G +G GE+G+ PG G G++GP+GPPG G G PG GP GSPG+PG+P D Sbjct: 1373 AGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGD 1432 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 V+++EIK++I QE++++F+ERMA + S+++ P M AA GRPGPPGKDG PG PG P Sbjct: 1433 MVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAP--GRPGPPGKDGAPGRPGAP 1490 Query: 1072 GPQGYRGQ------------------KGERGEPGIGLPGSPGLPG--------------- 1098 G G GQ KGE+G+ GIG+ G GLPG Sbjct: 1491 GSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQGPPGYGKMGA 1550 Query: 1099 ---TSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 G+PG PG PGP G PG +G CNP DC Sbjct: 1551 TGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDC 1583 Score = 493 bits (1269), Expect = e-139 Identities = 325/832 (39%), Positives = 395/832 (47%), Gaps = 147/832 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGE-----NGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG 346 G+ GLPG G PG KG +GEPG G G PG PG G QG G +G G GE+G Sbjct: 762 GQPGLPGVQGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKG 821 Query: 347 EKGDPALAGLNG--------------ENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP-- 390 +G P + G G +G +G G G PG KG +G+ G PG + P Sbjct: 822 AQGSPGVKGATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQ 881 Query: 391 GSLGIQGPQGPPGK-EGQRGRRGKTGPPGKPGPPGPPGPPGIQGI--HQTLGGYYNKDNK 447 G L G G PG G + G GPPG PGPPGPPG PG+QG+ + L G + Sbjct: 882 GDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAE 941 Query: 448 GN----DEHEAGGLKGD--KGETGLPGFPGSVGPKGQKGEPG---------------EPF 486 ++H + GD +G+ PG+ G KG +G PG P Sbjct: 942 LGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPR 1001 Query: 487 TKGEKGDR--GEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544 + +GD G+PG +GS G+ G PG PG G G PG++G G G +GP G PG VG Sbjct: 1002 AEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGS 1061 Query: 545 PGEHGIPGKQGIKG---EKGDPG--------GIIGPPGLPGPKGEAGPPG----KSLPGE 589 PG G+ G++G+ G +KG+PG G GPPGLPG KGE G G K PG Sbjct: 1062 PGLPGLQGERGLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGP 1121 Query: 590 PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI----------GIPGRTGAQGPAG- 638 PG +G PG PGP GP+GERG G G GD G QG G PG+ G+ GP G Sbjct: 1122 PGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGP 1181 Query: 639 -----EPGIQGPRGLPGLPGTPGTPGN------DGVPGRDGKPGLPGPPGDPIALPLLGD 687 GI+GP GLPG PG PG PG DG+ G+DGKPGL G PG L+G Sbjct: 1182 QAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGP 1241 Query: 688 IGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKG 747 G K G+ +PG K + G+ G G G+ + G +GP+G PG PG GP G Sbjct: 1242 PG--FKGKTGH--PGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPG 1297 Query: 748 SKGERGYPGIP--GEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGP 805 G+ G GI G KGD G G G+ G PG GPPG G G PG GA G++G G Sbjct: 1298 PPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGK 1357 Query: 806 PGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG------PPGPPGPKGDPGPVGEP 859 G GPPGP G P G KG +P PG P GPPGP G+ G G P Sbjct: 1358 QGFYGPPGPKGDP--GAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAP 1415 Query: 860 GAMGLPGLEGFPGVKGDR---------------------------------------GPA 880 G G PGL G PG GD G Sbjct: 1416 GPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRP 1475 Query: 881 GPPGIAGMSGKPGAPGPPGVPGE---PGERGPVGDIGFPGPEGPSGKPGIN--GKDGIPG 935 GPPG G G+PGAPG PG+PG+ G +G G G PG +G G GI G++G+PG Sbjct: 1476 GPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPG 1535 Query: 936 AQGIMGKPG-----DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982 G G PG GP G++G GIPG G G+ GK G G M Sbjct: 1536 PPGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAM 1587 Score = 413 bits (1061), Expect = e-115 Identities = 299/771 (38%), Positives = 366/771 (47%), Gaps = 147/771 (19%) Query: 456 GLKGDKGETGLPGFPGSVGPKGQKGE------PGEPFTKGEKGDRGEPGVIGSQGVKGEP 509 G KG KGE GLPG PGS G KG +G P P E G +G KGE Sbjct: 334 GPKGGKGERGLPGPPGSKGEKGARGNDCVRISPDAPLQCAE----------GPKGEKGES 383 Query: 510 GDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQ---GIKGEKGDPGGI 566 G GP GL GS G KGQ+G G G +G PG PG G PG+ G KG+KGDPG Sbjct: 384 GALGPSGLPGSTGEKGQKGEKGDGGIKGVPGK---PGRDGRPGEICVIGPKGQKGDPG-F 439 Query: 567 IGPPGL---PGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623 +GP GL PGP G GPPG LPG PG G P PGP+G KG G+PG G PG Sbjct: 440 VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGP--PGPKGDKGSSGIPGKEG-PG----- 491 Query: 624 GIGIPGRTGAQGPAGEP---------GIQGPRGLPGLPGTPGTPGNDGVPGRD--GKPGL 672 G PG+ G +G G+P G Q GLPG PG G PG D VP R G G+ Sbjct: 492 --GKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPG-DPVPARGDPGIQGI 548 Query: 673 PGPPGDPI--------ALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDS 724 G G+P A L+ GA G+ +PGL G G GE G + Sbjct: 549 KGEKGEPCLSCSSVVGAQHLVSSTGA--SGDVGSPGFGLPGLPGRAGVPGLKGEKGNF-- 604 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGP 778 G+ GP G PG PG GP G KG +G P P + GD + +PG G G Sbjct: 605 ----GEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGE 660 Query: 779 TGPPG--LMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPF---------------NE 821 GPPG L G+ G G G KG+KG G PG PG PG G P + Sbjct: 661 PGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEK 720 Query: 822 RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG-----EPGAMGLPGLEGFPGVKGD 876 +G ++ ++G V G PG PGPKG+ GP G +PG GLPG++G PG+KG Sbjct: 721 GDGCTACPSLQG--TVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGV 778 Query: 877 RGPAGPPG--IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934 +G GPPG + G G+PGAPG PG+ G PG RGP G G G +G G G G G P Sbjct: 779 QGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPP 838 Query: 935 GAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPG-----------LTGMKGA----I 979 GA + G PG G +G+ G +G PG++G +GE+G+PG +GM GA + Sbjct: 839 GAS-VSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWM 897 Query: 980 GPMGPPGNKGSMGSPGHQGPPGSPGIPGIPAD-------AVSFEEIKKYINQEVLRIFEE 1032 G PG +G G PG GPPG PG+ G+P + ++ E I Q +L+ Sbjct: 898 GSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICG 957 Query: 1033 RMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPG------------DPGPQGYRGQK 1080 Q P ++ G G G+PG PG P + RG Sbjct: 958 DCVQ--GQRAHPGYLV------EKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDN 1009 Query: 1081 GERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 E G+PG GSPGLPG PG PG G +GPPG G P + P Sbjct: 1010 SE-GDPGC--VGSPGLPGP-----PGLPGQRGEEGPPGMRGSPGPPGPIGP 1052 Score = 407 bits (1045), Expect = e-113 Identities = 272/732 (37%), Positives = 319/732 (43%), Gaps = 174/732 (23%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQ-------------------KGEQG 331 +G G+PG PG PG G +G PG NGL G PG + +G++ Sbjct: 906 QGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRA 965 Query: 332 FEGSKGETGEKGEQGEKGDPAL--------------------------------AGLNGE 359 G E GEKG+QG G P L GL G Sbjct: 966 HPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGP 1025 Query: 360 NGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLG---IQGPQGPPGKEGQRGRRGKTGP 416 GL G G GPPG +G G GP GPP PG++G + G QG G G G +G+ GP Sbjct: 1026 PGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDKGEPGP 1085 Query: 417 PGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPK 476 PG+PG PG GPPG+ GI G + KG G G GLPG PG GP+ Sbjct: 1086 PGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEP--------GPPGSEGLPGPPGPAGPR 1137 Query: 477 GQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG---DPGPPGLI---GSPGLKGQQGSA 530 G++G G KG++G +G+PG G G G PG PGPPG GS G++G G Sbjct: 1138 GERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLP 1197 Query: 531 GSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPG---------LPGPK 576 GS GP GPPG G G G+ GK G G +GDPG G++GPPG LPGPK Sbjct: 1198 GSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPK 1257 Query: 577 GEAGPPGK-SLPGEPGLDGNPGAPGPRG---PKGERGLPGVHGSPGDIGPQGIGIPGRTG 632 G+ G PG G PG +G PGA GP+G P G G PG G PG G +G+ G G Sbjct: 1258 GDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRG 1317 Query: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL------PGPPGDPIALPLLG 686 A G G G+ G G PG PG PG PG DG G++G PG PGP GDP A G Sbjct: 1318 ATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKG 1377 Query: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 G KG G G PGK SM G GP G G PG GP Sbjct: 1378 QAG-------------------EKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPS 1418 Query: 747 GSKGERGYPG------------------------------------------IPGEKGDE 764 GS G G PG PG G Sbjct: 1419 GSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPP 1478 Query: 765 GLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA------KGEKGS-----DGPPGKPGPPG 813 G G PG PGAPG G PG +GR G G G KGEKG G G PGPPG Sbjct: 1479 GKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPG 1538 Query: 814 PPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAM----GLPGLEG 869 P G P + G + G + PG PGPPGP G PG G +P + Sbjct: 1539 PQGPPGYGKMGAT------GPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPMEQQ 1592 Query: 870 FPGVKGDRGPAG 881 +P +K +GP G Sbjct: 1593 YPPMKTMKGPFG 1604 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 686 bits (1771), Expect = 0.0 Identities = 410/965 (42%), Positives = 495/965 (51%), Gaps = 139/965 (14%) Query: 244 EISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSP 303 E D P D + N+ A +S LP+ + QC G A G+ Sbjct: 166 ESLDLLGPRTDPWENVDQGAQGACGRGNTSVLPSS--VAPQCSMPKGTGHE-FSAALGTQ 222 Query: 304 GQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLK 363 G + + + + A PG K GE GE+GE G G P GL+ Sbjct: 223 GPADQRADARASCILAAKTAPGLKQ------LNGEPGERGEDGLPGKP---------GLR 267 Query: 364 GDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPP 423 G++G G G GEKG+ G PG P PG G +G QG G+ G G +G G G+ GP Sbjct: 268 GEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 327 Query: 424 GPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPG 483 GPPG PG + T P PG GPKG+KG+PG Sbjct: 328 GPPGLPGTTSLF----------------------------TPHPRMPGEQGPKGEKGDPG 359 Query: 484 EPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG---PRGPPG 540 P GE G +G PG +G QG G PG G G G+PG G G+ G +G P GPPG Sbjct: 360 LP---GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPG 416 Query: 541 DVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGN 595 VG PG G PGK G +GEKG G G +GP G PG G GPPGK GEPGL G+ Sbjct: 417 SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 476 Query: 596 PGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTP 655 PG PGP G KG+RG PG+ GSPG G GIG+ G G GP G+ G G RGLPG PG Sbjct: 477 PGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 536 Query: 656 GTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS---VPGLKSNKGE 712 G G RDG L P GDI L K+ C +C +PGL KG+ Sbjct: 537 GPAG------RDGLSSLLSP----------GDINLLAKDVCNDCPPGPPGLPGLPGFKGD 580 Query: 713 EGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGI 772 +G G+PG+ + +KG+ GP G PG PG GP+GS+GERG G G+KGD+G G+PG Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 773 PGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE----RNGMSSL 828 G PG GPPG G G GP G +G G +GPPG GP G PGIP E R+G Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 700 Query: 829 YKIKGGVNVPSYPGPPG---PPGPKGD------PGPVGEPGAMGLPGLEGFPGVKGD--- 876 G P PGP G PPG KG PGP GE GAMGLPG EG PG GD Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGP 760 Query: 877 ------RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGK 930 +GP GPPG G G PG PGP G PG+ G +G G G PG GP G PG G+ Sbjct: 761 TGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGE 820 Query: 931 DGIPGAQGIMGKPGDRGPKGERGDQGIPGDRG---SQGERGKPGLTGMKGAIGPMGPPGN 987 G+PG +G+ GKPG+ G KGERGD GI GD+G +G+ G PG+ G KG G MGP G Sbjct: 821 KGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGL 880 Query: 988 KGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAM 1047 G G G GPPG PG PG+ ++ S E +++ I +E+ + E R+A L+Q+ PA M Sbjct: 881 PGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMP-PAYM 939 Query: 1048 LAAQAY-GRPGPPGKDGLP---GPPGDP---------------GPQGYRGQKGERGEPGI 1088 ++Q G PGPPGKDGLP GP G+P GP+G RG KG+ G PG+ Sbjct: 940 KSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGV 999 Query: 1089 GL---------PGSPGLPGTSALGLPGSPGA---------PGPQGPPGPSGRCNPEDCLY 1130 GL PG PG PG + GLPG PG PG GPPGP G+C+P C Y Sbjct: 1000 GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAY 1059 Query: 1131 PVSHA 1135 S A Sbjct: 1060 FASLA 1064 Score = 486 bits (1252), Expect = e-137 Identities = 335/915 (36%), Positives = 401/915 (43%), Gaps = 239/915 (26%) Query: 366 LGPHGPPGP---KGEKGDTGPPGPPALPGSLGIQ---------------GPQGPPGKEGQ 407 LGP P +G +G G LP S+ Q G QGP + Sbjct: 171 LGPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRAD 230 Query: 408 R------------GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG 455 G + G PG+ G G PG PG++G +G E Sbjct: 231 ARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRG---EIG-----------EQGLA 276 Query: 456 GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPP 515 G G+KGE GLPG PG G +G+KG+ +GEKG+ G PG+ G +G KGE G GPP Sbjct: 277 GRPGEKGEAGLPGAPGFPGVRGEKGD------QGEKGELGLPGLKGDRGEKGEAGPAGPP 330 Query: 516 GLIGSPGL-KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPG 574 GL G+ L G GP+G GD GLPGE PG QG GE G P G GPPG G Sbjct: 331 GLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGE---PGLQGRPGELG-PQGPTGPPGAKG 386 Query: 575 PKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQ 634 +G G PG + G PG G+ GAPGP GP G G PG+ G+PG G +G GA Sbjct: 387 QEGAHGAPGAA--GNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERG-----EKGAA 439 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKN 694 G G PG GPRG PG PG PG PG G+DG+PGL G PG P L GD GA Sbjct: 440 GEEGSPGPVGPRGDPGAPGLPGPPGK----GKDGEPGLRGSPGLPGPLGTKGDRGA---- 491 Query: 695 FCGNCQASVPGLKSNKGEEG--GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG-- 750 +PG ++G+ G AG PG KG G RG PG PG +GP G G Sbjct: 492 ------PGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS 545 Query: 751 ----------------------ERGYPGIPGEKGDEGLQGIPG---IPGAPGPTGPPGLM 785 G PG+PG KGD+G+ G PG G G GPPGL Sbjct: 546 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 605 Query: 786 GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPG 845 G G GP G++GE+G+DG G+ G G PG+P G + P PGPPG Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP--------------GFMGPPGNPGPPG 651 Query: 846 ---------PPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG---PAGPPGIAGMSGKPG 893 PPG +G PG G PG G GL G PG +G G GPPG G +G+PG Sbjct: 652 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711 Query: 894 APGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERG 953 PGP G G PG +G GD G PGP G SG G+ G++G+PG G G G +GP+G RG Sbjct: 712 LPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRG 771 Query: 954 D---------------QGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 G PG +GS+GE G PGL G +GP GPPG G G PG +G Sbjct: 772 PPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF---LGPRGPPGEPGEKGVPGKEG 828 Query: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 PG PG PG + IK G GP Sbjct: 829 VPGKPGEPGFKGERGD-PGIK----------------------------------GDKGP 853 Query: 1059 PGKDGLPGPPGDPGPQGYRGQKGERGEPG----IGLPGSPGLPG---------------- 1098 PG G PG PG PG +G+ G G +G PG +G PG PG PG Sbjct: 854 PGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRR 913 Query: 1099 --------------------------TSALGLPGSPGAPG---------PQGPPGPSGRC 1123 S+ G PG PG PG P G PG G+ Sbjct: 914 LIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQG 973 Query: 1124 NPEDCLYPVSHAHQR 1138 E P+ +R Sbjct: 974 GLEGPSGPIGPKGER 988 Score = 452 bits (1164), Expect = e-127 Identities = 281/710 (39%), Positives = 333/710 (46%), Gaps = 144/710 (20%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G AG PGAPG G G G PG G G G PG+ GE+G +G+ GE G G G +GDP Sbjct: 395 GAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 454 Query: 352 ALAGL-----NGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGS-----LGIQGPQGP 401 GL G++G G G G PGP G KGD G PG P PGS +G+ GP GP Sbjct: 455 GAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGP 514 Query: 402 PGKEGQRGRRGKTGPPGKPGPPGP---------------------------PGPPGIQGI 434 G G +G G G PG PGP GP PGPPG+ G+ Sbjct: 515 SGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGL 574 Query: 435 HQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDR 494 G G + E G KG+ G GLPG PG GP+G +GE G G+KGD+ Sbjct: 575 PGFKGDKGVPGKPGREGTE--GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQ 632 Query: 495 GEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQ 554 G PGV G G G PG PG G+ G+ G G QGS G GP GP G GLPG G GK+ Sbjct: 633 GHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKE 692 Query: 555 GIKGEKGDPG--GIIGPPGLPGPKGEAGPPG-------------------KSLPGE---P 590 G G+ G PG G G PGLPGP+G GPPG LPG+ P Sbjct: 693 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP 752 Query: 591 GLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQG---PR 646 G DG+ G GP+GP+G RG PG +GSPG G G G PG+ G++G G PG+ G PR Sbjct: 753 GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 812 Query: 647 GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGL 706 G PG PG G PG +GVPG+ G+PG G GDP G+ Sbjct: 813 GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDP-------------------------GI 847 Query: 707 KSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD--- 763 K +KG GG G+PG KG G GP G+PG GP G G G PG PG +G+ Sbjct: 848 KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPS 907 Query: 764 --------------------------------EGLQGIPGIPGAPGPTGPPGL---MGRT 788 + QG PG PG PG G PG MG Sbjct: 908 METLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP 967 Query: 789 GHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPG 848 G PG G +G G GP G+ G G PG P G+ ++G + P PG PG PG Sbjct: 968 GRPGQGGLEGPSGPIGPKGERGAKGDPGAP-----GVG----LRGEMGPPGIPGQPGEPG 1018 Query: 849 PKGD-----PGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPG 893 D PGP GE G G PGL G PG G P+ A ++ +PG Sbjct: 1019 YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAARPG 1068 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 652 bits (1681), Expect = 0.0 Identities = 418/1005 (41%), Positives = 481/1005 (47%), Gaps = 217/1005 (21%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG---- 346 KGE G PG G PG+ G G+PG GL G PG+PG+ G G +G KG+TG G G Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 347 ---------EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPGSLGI 395 EKG+ L GL GE G +G G GPPG G G GPPGPP PG G Sbjct: 348 RPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Query: 396 QGPQGPPG--------KEGQRGRRGKTGPPGKPGP----------PGPPGPPGIQGIHQT 437 +G +GPPG +GQ G G GPPG GP PGPPGPPG G Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467 Query: 438 LGGYYNKDNKGNDEHEA--GGLKGDKGETGLPGFPG------------------SVGPKG 477 G K +KG+ G+ G G+ GLPG PG + GPKG Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 478 QKGEPGEPFTKGEKGDRGEPGVI----GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSM 533 G PG P G G +GEPG I G +G KGE G PG PGL G PG GQ G G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP 587 Query: 534 GPRGPPGDVGLPGEHGIPGKQGIKG--------------------EKGDPG--GIIGPPG 571 GP+G PG + GE G PG G+ G EKG G G G PG Sbjct: 588 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG 647 Query: 572 LPGPKGEAGP----PGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626 +PGPKG+ G PGK LPG PG DG+ G PG G G+ GLPG+ GS G+ G GIG Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707 Query: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPG--LPGPPGDPIA 681 +PG GP G PGI GP G PG PG G PG G PG G+PG LPGPPG P Sbjct: 708 LPG---PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 682 LPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPG 741 G +G PG G G G PG + G GP GPPG+PG Sbjct: 765 PGFKGALGP-------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 742 -----REGPKGSKGERGYPG---IPGEKGDEGLQGI-----------PGIPGAPGPTGPP 782 GP G G G PG IPGEKGD G G+ PGIPGAPGP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 783 GLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 G G G G +G G KG G G PGPPGP GIP R+G+ L G P PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPGLKGDDGLQGQPGLPG 935 Query: 843 PPGPPGPKGDPGPVGEPGAM--------------GLPGLEGFPGVKGDRGPAGPPGIAGM 888 P G G KG+PG G PG M GLPG+ G G KG +G G PG G+ Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 889 SGKPGAPGPPG------VPGEPGERGP------VGDIGFPGPEGPSGKPGINGKDGIPGA 936 SG+PG PGPPG +PG+PG GP +GD+GFPGP+G G PG +G G PG+ Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055 Query: 937 QGIMGKPGDRG--------------PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982 G+ G+ GD+G PKGE G G PG+ G +G G PGL G+ G G Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 983 GPPGNKGSMGSPGHQGPPG---SPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G+PG GP G PG PG+P + Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE---------------------------- 1147 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGT 1099 P + G+PGPPG+ G PG G PGP G QKGE G+PG G PG PGLPG Sbjct: 1148 ----PGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG---QKGEPGQPGFGNPGPPGLPGL 1200 Query: 1100 SAL-------GLPGSPGAPGP------------QGPPGPSGRCNP 1125 S G+PG+PG PGP QGPPGP G P Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Score = 639 bits (1649), Expect = 0.0 Identities = 412/915 (45%), Positives = 474/915 (51%), Gaps = 138/915 (15%) Query: 292 GEAGLPGAPGS---PGQKGHKGE---------PGENGLHGAPGFPGQKGEQG----FEGS 335 G GLPG PGS PGQKG KG+ PG G GAPGFPG KGE G F G Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGS 392 KG+ GE G G G P L G G++GL G GP G PG KGE+G G PG P LPG+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616 Query: 393 LGIQGPQG--PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450 +G GP G PPG G++G +G G PG+PG PGP G PG QT+ Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-----QTI-----------T 660 Query: 451 EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 + GL G+ G G G PG G GQ G PG P +KGE G G G+ G G KG PG Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPG 719 Query: 511 DPGPPGLIGSPG---LKGQQGSAGSMGPRGPPGDV--GLPGEHGIPGKQGIKGEKGDPG- 564 PGPPG G+PG L+G G G GP+G PG G PG G+PG +G G KGD G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 565 -GIIGPPG------LPGPKGEAGPPGKSLP-GEPGL-----DGNPGAPGPRGPKGERGLP 611 G GPPG LPGPKG+ GP G+ P G PGL G PG PG GP G+ GL Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 612 GVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG 671 G+ G GD GP G+ +PG G +G G PG GP G PG PG PG G G PG G+ G Sbjct: 840 GIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 672 LPGPPGDPIALPLLGDIGAL-LKNFCG-NCQASVPGL---KSNKGEEGGAGEPGKYDS-- 724 + GPPG P L + G G LK G Q +PG K +KGE G G PG D Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 + KG+ G G PGIPG GPKG Y G+PG+ G GL G PG+PG PGP G PGL Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKG------YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 785 MGRTGHPGPTGAKG---EKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKG-----GV 835 G+ G GP G KG + G GP G GPPGP G+P + G+ KG + Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073 Query: 836 NVPSYPGP---PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP 892 +P PGP PG PG G+PG G G GLPGL G PG KG G G PG G G Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 893 GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 G GPPG PG PGE GPVG G PG GP G+ G G+DGIPG G G+PG G G Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG-FGNP 1192 Query: 953 GDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADA 1012 G G+PG G +G+ G PG+ G G GP G PG G PG QGPPG PG PG PA Sbjct: 1193 GPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGF---PGVQGPPGPPGSPG-PA-- 1246 Query: 1013 VSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY-GRPGPPGKDGLPGP---P 1068 L+ P Q GRPGP G GLPGP P Sbjct: 1247 ----------------------------LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPP 1278 Query: 1069 GDPGPQGYRGQKGERGEPGI-------------GLPGSPGLPGTSAL----GLPGSPGAP 1111 G PG G +G+KG G+PG+ GL G+PG PG + + GLPG PG P Sbjct: 1279 GLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP 1338 Query: 1112 GPQGPPGPSGRCNPE 1126 G +GP G G PE Sbjct: 1339 GMKGPSGVPGSAGPE 1353 Score = 637 bits (1642), Expect = 0.0 Identities = 408/957 (42%), Positives = 473/957 (49%), Gaps = 156/957 (16%) Query: 291 KGEAGLPGAPGSPGQ-------------KGHKGEPGENGLHGAPGFPGQKGEQGFEGSKG 337 KGE GL G PG PGQ KG +G PG+ G G PG G G G G KG Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKG 286 Query: 338 ETGEKGEQGEKGDPALAGLNGENG---LKGDLGPHGPPG---PKGEKGDTGPPGPPALP- 390 E GE+GE G++G P G NG+ G L GD G G PG KG+KGDTGPPGPP L Sbjct: 287 EKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI 346 Query: 391 ---------GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG-----PPGPPGIQGIHQ 436 G G G G PG++G+RG G GPPG PGPPG PPGPPG G Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406 Query: 437 TLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPK-------GQKGEPGEPFTKG 489 G ++ G GL G G GLPG PG GP + G PG P + G Sbjct: 407 QKG---DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 490 EKGDRGEPGVIGSQG----------VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP 539 +KG +GE GV G +G + G PG PG PGL G PG G G G G G Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK----SLPGEPGLDGN 595 G GLPG G PG G G KG+PG I+ PG+ G KGE G PG LPG PG DG Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Query: 596 PGAPGP------------RGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQG------PA 637 PG PGP RGP G GLPG+ G+ G +GP G G PG G +G Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643 Query: 638 GEPGIQGPRGLPGL----PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLK 693 G+PGI GP+G PG PG PG PGN PGRDG GLPG PG P L G G+ K Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGN---PGRDGDVGLPGDPGLPGQPGLPGIPGS--K 698 Query: 694 NFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSK--GE 751 G +PG KG G G PG + R G GP GPPG PG +G G G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG- 810 G PG+PG KG G +G G PG PGP G GL G G G G G+ G GPPG PG Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 811 ----PPGPPGIPFNERNGMSSLYKIKG--------GVNVPSYPGPPGPPGPKGDPGPVGE 858 PPGPPGIP G L+ I G G++VP PG G PG G PGP+G Sbjct: 819 GVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 859 PGAMGLPG---LEGFPGVKGDRG---PAGPPGIAGMSGKPGAPG---------PPGVPGE 903 PG+ GLPG GFPG KG+ G P GPPG G+ G+ G PG PG+PG Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 904 PGERGPVGDIGFPGPEGP-----------SGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 GE+G G+ G PGP GP G+PG+ G G+ G +G G PGD G G Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS 996 Query: 953 GDQGIPGDRGSQGERGKPGLTGM------KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIP 1006 G G+PG G +G G PG G+ KG IG MG PG +G G PG G PG PG P Sbjct: 997 GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056 Query: 1007 GIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPG 1066 G+P ++ +S + LP G PG PG G+ G Sbjct: 1057 GLPGQK------------------GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 1067 PPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 GDPG G G G +G+PG+ G PG+PG PG + G PG+PG PG GP G G Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Score = 629 bits (1622), Expect = e-180 Identities = 396/915 (43%), Positives = 451/915 (49%), Gaps = 105/915 (11%) Query: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGH-----------KGEPGENGLHGAPGF 323 LP K + I KGE G PG PG PG G+ G GE G+ G G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642 Query: 324 PGQKGEQGFEGSKGET----GEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG 379 PGQ G G +G G+T G+ G G G GL G+ GL G G G PG KGE G Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702 Query: 380 --DTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGP--------PGPPGPP 429 G PGPP G GI GP G PG G+ G G GPPG PGP PGPPGPP Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762 Query: 430 GIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP---- 485 G+ G LG ++ G G G G GLPG G VGP GQ G G P Sbjct: 763 GLPGFKGALGPKGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 486 -FTKGEKGDRGEPGVIGS---QGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPP 539 +G G G PG IG G+ GE GDPGPPGL G PG +G G G+ GP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGA 598 G GLPG+ G G G KGE G++GPPG PGP G G G L G+ GL G PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEM----GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933 Query: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTP 658 PGP G KG +G PG+ G PG + P +G G G G G PG+ GP+G GLPG PG P Sbjct: 934 PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993 Query: 659 GNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G G PG G PG G PG P L+G G LK G+ PG + +G G +G Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--LKGTIGD--MGFPGPQGVEGPPGPSGV 1049 Query: 719 PGKYDSMARKGDIGPRGPPGI-----PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIP 773 PG+ S G G +G PGI PG GPKG G GYPG PG KG G G+PG+P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 774 GAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGP---------PGIPFNE-RN 823 G PG G PGL G G PGP G KG G G PG PG PGP PG P + + Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 824 GMSSLYKIKGGVNVPSYP--GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG 881 G + G P P G PGPPG G G G+ G G+PG G PG KG+ G G Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 882 PPGIAGMSGKPGAPGP--------PGVPGEPGERGPVGDIGFPGPEGPSGKP---GINGK 930 PG+ G G PG+PGP PG G PG GP G G PGPEGP G P GI G+ Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGE 1289 Query: 931 DGIPGAQGIMGKP---GDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN 987 G PG G+ G P GD+GP G +G+ G PG G +G+ G PG+ G G GP G PG+ Sbjct: 1290 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1349 Query: 988 KGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAM 1047 G G PG GPPG PG+PG ++ + P Sbjct: 1350 AGPEGEPGLIGPPGPPGLPGPSGQSI----------------------IIKGDAGPPGIP 1387 Query: 1048 LAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPG 1106 G PGP G GLPGP G PG G G G G G G PG PG PGT GL G Sbjct: 1388 GQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDG 1445 Query: 1107 SPGAPGPQGPPGPSG 1121 PG G QGPPGP G Sbjct: 1446 PPGPDGLQGPPGPPG 1460 Score = 617 bits (1591), Expect = e-176 Identities = 437/1134 (38%), Positives = 505/1134 (44%), Gaps = 324/1134 (28%) Query: 284 QCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKG 343 +C C KGE G G PG +GH G PG G G PG GQKG+ G G G G +G Sbjct: 37 KCDCSGIKGEKG---ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 344 EQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P GL G G G GP G PG G KG+ G PG P PG +QGP GPPG Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG---LQGPPGPPG 150 Query: 404 KEGQRGRRGK---TGPPGKPGPPGPPGPPGIQGIHQTLG-----------GYYNKDN--- 446 G +G G + PG G PG PGPPGIQG+ G G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 447 ----KGNDEHEAGGLKGDKGETGL---PGFPGSV-------------------------G 474 KGN G KG+KGE GL PG PG + G Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 475 PKGQKGEPGEP-FTKGEKGDRGEPGVIGSQGVKGE------PGDPGPPGLIGSPGLKGQQ 527 P G +G PG P KGEKG++GEPG G G GE PG PG PG G PG G++ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 528 GSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP-- 575 G G GP GPPG +G G G+PG G KGE+G P GI GPPGLPGP Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGLPGPPG 389 Query: 576 ------------------KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKG----------- 606 KG+ GPPG S+PG PGLDG PGAPG GP G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 607 --ERGLPGVHGSPGDIGPQG--------------------------------------IG 626 E G PG GSPGD G QG +G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 627 IP------GRTGAQGPAGEPGIQGPRGLPGLPGT-------------------------P 655 P G+ GA GP G PGI G G PG PG+ P Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 656 GTPGNDGVPGRDGKPGLP---------------GPPGDPIALPLLGDIGAL--------- 691 G PG G PG+DG PGLP GPPG+P L G+IG + Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 692 ------LKNFCGN-CQASVPGLKSNKGEE-GGAGEPGKYDSMARKGDIGPRGPPGIPGR- 742 ++ GN Q +PG K + G+ G+PG + R GD+G G PG+PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 743 --EGPKGSKGERGYPGI--PGEKGDEGLQGIPGIPGAP---------GPTGPPGLMGRTG 789 G GSKGE G PGI PG G +G GIPG PGAP GP GPPG G G Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 790 H--------PGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNERNGMSSLYKIKGGVNVP 838 PGP G G KG+ GP G PGPPGPPG R G+ L KG V Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPKGDVGPN 804 Query: 839 SYPGPPGPP-----GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGP-----AGPPGIAGM 888 PGP GPP G +G PGP G PG +G PGL G PG KGD GP GPPG G Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 889 SGKPGAPGP------PGVPGE------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 G PGAPGP PG+PG+ PG +G +G +G PGP GP G PG +G G+ G Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 937 QGIMGKPGDRGPKGERGDQGIPG-----------DRGSQGERGKPGLTGMKGAIGPM--- 982 G+ G+PG GP GE+G +G PG GS+GE+G+PGL G+ G GP Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 983 ---GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G PG GPPG G PG+P + I + + Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG--------------QPGLIGPPGLKGTIG 1030 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGE--------------RGE 1085 + P G GPPG G+PG PG PG G +G KG+ +GE Sbjct: 1031 DMGFPGPQ------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1086 PG-------------IGLPGSPGLPGT-SALGLPGSPGAPGPQGPPGPSGRCNP 1125 PG +G PG PGLPGT A G PG PG PG GPPGP G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 615 bits (1585), Expect = e-175 Identities = 412/981 (41%), Positives = 469/981 (47%), Gaps = 194/981 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KG+ G+PG PG G +G G PG G G PG PG G G +G G G KGE+G G Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136 Query: 351 PALAGLNGENGLKGDLGPHGPPG---------PKGEKGDTGPPGPPALPGSLGIQGPQGP 401 P GL G G G G G PG PKG G GPPG LPG GI GP GP Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196 Query: 402 PGKEGQRGRRGKTGPPGKPGPPG--------PPGPPGIQGIHQTLG--GYYNKDNKGND- 450 PG G G GPPG PGP G P G G QG+ G G ++ + D Sbjct: 197 PGPPGLMG---PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDV 253 Query: 451 EHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE 508 E + G GL GD+G G PG G GP G GE GE +GE G RG+PG G G G Sbjct: 254 EFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 509 PGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKG 558 PG PG PG G PG G++G G GP GPPG +G G G+PG G KG Sbjct: 312 PGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Query: 559 EKGDPGGIIGPPGLPGP--------------------KGEAGPPGKSLPGEPGLDGNPGA 598 E+G PG I GPPGLPGP KG+ GPPG S+PG PGLDG PGA Sbjct: 372 ERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430 Query: 599 PGPRGPKG-------------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEP----- 640 PG GP G E G PG GSPGD G QG G +G G+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG-----EQGVKGDKGDTCFNCI 485 Query: 641 --GIQGPRGLPGLPGTPGTPGNDGVPGRDGK------------PGLPGPPGDPIALPLLG 686 GI GP G PGLPG PG PG+ G PG+ G+ PG+PG PG P G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG---------------------KYDSM 725 + G +L + PG+K +KGE G G PG + + Sbjct: 546 EPGDIL---------TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGY--PGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 KG+ GP G PG+PG G G G G+ PG GEKG +G+ G PG PG PGP G PG Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 784 LM----GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G+ G PG G G+ G G PG PG PG PGIP + KG +P Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS-----------KGEPGIPG 705 Query: 840 YPGPPGPPGPKGDPGPVGEPGAMGLPG---LEGFPGVKGDRGPAGPPGIAGMSGKPGAPG 896 G PGPPGPKG PG G PGA G PG LEG PG G GP G PG A PG PG Sbjct: 706 I-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA----LPGPPG 760 Query: 897 PPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD-- 954 PPG+PG G GP GD GFPGP GP G+ G++G G G G G+PG GP G G Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGV 820 Query: 955 QGIPGDRGSQGERGKPGLTGM---KGAIGPMG-----PPGNKGSMGSPGHQGPPGSPGIP 1006 QG PG G G G+PGL G+ KG GP G PPG +GS G PG GP G PG P Sbjct: 821 QGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880 Query: 1007 GIP--ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 G+P A A F K + + P + G PG G DGL Sbjct: 881 GLPGKAGASGFPGTKGEMGM-------------MGPPGPPGPLGIPGRSGVPGLKGDDGL 927 Query: 1065 PGPPGDPGPQGYRGQKGERGEPG---------------IGLPGSPGLPGTSA----LGLP 1105 G PG PGP G +G KGE G PG G PG PG+PG S GLP Sbjct: 928 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987 Query: 1106 GSPGAPGPQGPPGPSGRCNPE 1126 G PG PG G PG G P+ Sbjct: 988 GDPGQPGLSGQPGLPGPPGPK 1008 Score = 599 bits (1545), Expect = e-171 Identities = 379/882 (42%), Positives = 429/882 (48%), Gaps = 133/882 (15%) Query: 283 DQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS--KGETG 340 D Q I G+ GLPG PG G G G+PG G G PG PG KGE G G G G Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713 Query: 341 EKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPG------- 391 KG G G P G G GL+G GP G PGPKGE G GPPGPP LPG Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773 Query: 392 --SLGIQGPQGPPGK---EGQRGRRGKTGPPGKPGPPGPPG--------PPGIQGIHQTL 438 G GP GPPG+ +G G +G GP G+PGP GPPG PPG GI + Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPI 833 Query: 439 G--GYYNKDNKGNDEHEAG-GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRG 495 G G + + D G + G GE G PG PG+ GP G G PG P G+ G G Sbjct: 834 GQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLP---GKAGASG 890 Query: 496 EPGVIGSQGVKGEPGDPGP---PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 PG G G+ G PG PGP PG G PGLKG G G G GP G+ G GE G+PG Sbjct: 891 FPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 553 KQG--------IKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 G KGEKG+PG + G PG+ GPKG G PG PG+PGL G PG PGP GP Sbjct: 951 PPGPMDPNLLGSKGEKGEPG-LPGIPGVSGPKGYQGLPGD--PGQPGLSGQPGLPGPPGP 1007 Query: 605 KGERGLPGVHGSPGDIGPQGI-------GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657 KG GLPG PG IGP G+ G PG G +GP G G+ G G PGLPG G Sbjct: 1008 KGNPGLPG---QPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064 Query: 658 PGNDGV--------PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSN 709 G+ G+ PG G+PGLPG PG+P +GD G +PG Sbjct: 1065 KGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL----------PGLPGTPGA 1114 Query: 710 KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769 KG+ G G PG KG GP G PG+PG GP G G G PG PGEKG G GI Sbjct: 1115 KGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGI 1174 Query: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLY 829 PG G G G PG G G PG G G+KG G PG PG PG PG G + Sbjct: 1175 PGPAGQKGEPGQPGF-GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPG-----PKGEPGFH 1228 Query: 830 KIKGGVNVPSYPGPPGPP--GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAG 887 G P PG PGP GPKG+PGP G PG PG GF G+ G GP G PG G Sbjct: 1229 GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGR---PGPTGFQGLPGPEGPPGLPGNGG 1285 Query: 888 MSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRG 947 + G+ G PG PG+PG PG +G D G PG +G G+PG+NG G PG G+ G PG +G Sbjct: 1286 IKGEKGNPGQPGLPGLPGLKG---DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1342 Query: 948 PKGERGDQGIPGDRGSQGERGKPGLTG-------MKGAIGPMGPPGNKGSMGSPGHQGPP 1000 P G G G G+ G G G PGL G +KG GP G PG G G PG QGP Sbjct: 1343 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ 1402 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPG 1060 G PG G P D + LP A G PG PG Sbjct: 1403 GLPGPTGPPGDP--------------------------GRNGLPGFDGAGGRKGDPGLPG 1436 Query: 1061 KDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSAL 1102 + G G G PGP GL G PG PGTS++ Sbjct: 1437 QPGTRGLDGPPGPD--------------GLQGPPGPPGTSSV 1464 Score = 489 bits (1260), Expect = e-138 Identities = 341/833 (40%), Positives = 389/833 (46%), Gaps = 126/833 (15%) Query: 401 PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA-GGLKG 459 P K G +G+ G G PG G PG PG G G + KG+D G KG Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKG 90 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIG 519 +G GLPGFPG+ G G G G P +G G G G G G G PG GPPG G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 520 SPGLKGQQGS---AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPG 571 PG+KG+ GS + GP+G PG G PG G+PG GI G G PG G GPPG Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 572 LPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRG-------------PKGERGLPGVHGSPG 618 LPGPKG G + GE G G G PGP G KG++GLPG G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 619 DIGPQG--------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP 670 G +G G G G G G+PG G G PG+PG PG PG G PGRDG+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 671 GL------PGPPGDPIALPLLG-DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 G PGPPG I P G IG GN +PGL KGE G G G Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEK-----GN--IGLPGLPGEKGERGFPGIQGPPG 383 Query: 724 SMARKGD--IGPRGPPGIPGREGPKGSKGERG--YPGIPGEKGDEGLQGIPGIPG----- 774 G +GP GPPG PG G KG +G G PG PG G G G+PG PG Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 775 --------APGPTGPPGLMGRTGHPGPTGAKGEKGS----------DGPPGKPGPPGPPG 816 PGP GPPG G G G G KG+KG GPPG+PG PG PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 817 IPFN-------ERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV------------- 856 P + G + KG +P PG PG PG KG+PG + Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 857 GEPGAMGLPGLEGFP---GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDI 913 G PGA GLPGL G P G+ G GP G PG G+ G PG PG+PG PG GP+G Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPP 623 Query: 914 GFPGPEGPSGKPGINGKDGIPGAQGI-------------MGKPGDRGPKGERGDQGIPGD 960 GF GP GP G+ GI G G PG GI GKPG G G GD G+PGD Sbjct: 624 GF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 961 RGSQGERGKPGLTGMKG-----AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGI--PADAV 1013 G G+ G PG+ G KG IG GPPG KG G PG G PG+PG G+ P Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 1014 SFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY-GRPGPPGK---DGLPGPPG 1069 F K + + L K + + G PGPPG+ DGLPGP G Sbjct: 743 GFPGPK---GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPG-TSALGLPGSPGAPGPQGPPGPSG 1121 D GP G G G G PGIG+ G PG PG +G PG G PG +G PGP G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 298 bits (764), Expect = 2e-80 Identities = 189/455 (41%), Positives = 220/455 (48%), Gaps = 75/455 (16%) Query: 715 GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGL-------- 766 G K D KG+ G RG PG+ G G G G G PG G+KGD+G+ Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 767 -QGIPGIPGAPGPTGPPGLMGRTGHPGP------TGAKGEKGSDGPPGKP---GPPGPPG 816 +G PG+PG PG G PG+ G G PGP G KGE+G G PG P GPPGPPG Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 817 IP-FNERNGMSSLYKIKGGVNVPSYPGPP---GPPGPKGDPGPV---GEPGAMGLPGLEG 869 IP G + + G P YPGPP G PGP G PGP+ G PG MG PG G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 870 FPGVKGDRGP--AGPPGIAGMSGKPGAPGPPGVPGEPGERGPV------GDIGFPGPEGP 921 PG KG+ G GP G G G G PGPPG E ++ P+ GD G PG GP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE--QKRPIDVEFQKGDQGLPGDRGP 268 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 G PGI G G PG G++G KGE+G+ G G G GE G+PG+ G+ G G Sbjct: 269 PGPPGIRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320 Query: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 G PG G G G GPPG PG+ IP +K + Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGTGITIGEK------------------GNI 361 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPP-----GDPGPQGY---RGQKGERGEPGIGLPGS 1093 LP G PG G GLPGPP G PGP G+ RGQKG+ G PGI +PG Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 1094 PGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 PGL G PG+PG PGP GP GP + E C Sbjct: 422 PGLDGQ-----PGAPGLPGPPGPAGPHIPPSDEIC 451 Score = 107 bits (266), Expect = 8e-23 Identities = 72/203 (35%), Positives = 81/203 (39%), Gaps = 67/203 (33%) Query: 947 GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH------QGPP 1000 G KGE+G++G PG G PGL G G GP GP G KG G PG +GPP Sbjct: 42 GIKGEKGERGFPG------LEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPG 1060 G PG PG P G PG PG Sbjct: 96 GLPGFPGTP--------------------------------------------GLPGMPG 111 Query: 1061 KDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-------LGLPGSPG 1109 DG PGP G PG G +G++G G PG G PG PG+PG LPG G Sbjct: 112 HDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171 Query: 1110 APGPQGPPGPSGRCNPEDCLYPV 1132 PG GPPG G P P+ Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPI 194 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 652 bits (1681), Expect = 0.0 Identities = 418/1005 (41%), Positives = 481/1005 (47%), Gaps = 217/1005 (21%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG---- 346 KGE G PG G PG+ G G+PG GL G PG+PG+ G G +G KG+TG G G Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 347 ---------EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPGSLGI 395 EKG+ L GL GE G +G G GPPG G G GPPGPP PG G Sbjct: 348 RPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Query: 396 QGPQGPPG--------KEGQRGRRGKTGPPGKPGP----------PGPPGPPGIQGIHQT 437 +G +GPPG +GQ G G GPPG GP PGPPGPPG G Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467 Query: 438 LGGYYNKDNKGNDEHEA--GGLKGDKGETGLPGFPG------------------SVGPKG 477 G K +KG+ G+ G G+ GLPG PG + GPKG Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 478 QKGEPGEPFTKGEKGDRGEPGVI----GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSM 533 G PG P G G +GEPG I G +G KGE G PG PGL G PG GQ G G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP 587 Query: 534 GPRGPPGDVGLPGEHGIPGKQGIKG--------------------EKGDPG--GIIGPPG 571 GP+G PG + GE G PG G+ G EKG G G G PG Sbjct: 588 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG 647 Query: 572 LPGPKGEAGP----PGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626 +PGPKG+ G PGK LPG PG DG+ G PG G G+ GLPG+ GS G+ G GIG Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707 Query: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPG--LPGPPGDPIA 681 +PG GP G PGI GP G PG PG G PG G PG G+PG LPGPPG P Sbjct: 708 LPG---PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 682 LPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPG 741 G +G PG G G G PG + G GP GPPG+PG Sbjct: 765 PGFKGALGP-------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 742 -----REGPKGSKGERGYPG---IPGEKGDEGLQGI-----------PGIPGAPGPTGPP 782 GP G G G PG IPGEKGD G G+ PGIPGAPGP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 783 GLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 G G G G +G G KG G G PGPPGP GIP R+G+ L G P PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPGLKGDDGLQGQPGLPG 935 Query: 843 PPGPPGPKGDPGPVGEPGAM--------------GLPGLEGFPGVKGDRGPAGPPGIAGM 888 P G G KG+PG G PG M GLPG+ G G KG +G G PG G+ Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 889 SGKPGAPGPPG------VPGEPGERGP------VGDIGFPGPEGPSGKPGINGKDGIPGA 936 SG+PG PGPPG +PG+PG GP +GD+GFPGP+G G PG +G G PG+ Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055 Query: 937 QGIMGKPGDRG--------------PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982 G+ G+ GD+G PKGE G G PG+ G +G G PGL G+ G G Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 983 GPPGNKGSMGSPGHQGPPG---SPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G+PG GP G PG PG+P + Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE---------------------------- 1147 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGT 1099 P + G+PGPPG+ G PG G PGP G QKGE G+PG G PG PGLPG Sbjct: 1148 ----PGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG---QKGEPGQPGFGNPGPPGLPGL 1200 Query: 1100 SAL-------GLPGSPGAPGP------------QGPPGPSGRCNP 1125 S G+PG+PG PGP QGPPGP G P Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Score = 641 bits (1653), Expect = 0.0 Identities = 409/923 (44%), Positives = 474/923 (51%), Gaps = 144/923 (15%) Query: 292 GEAGLPGAPGS---PGQKGHKGE---------PGENGLHGAPGFPGQKGEQG----FEGS 335 G GLPG PGS PGQKG KG+ PG G GAPGFPG KGE G F G Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGS 392 KG+ GE G G G P L G G++GL G GP G PG KGE+G G PG P LPG+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616 Query: 393 LGIQGPQG--PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450 +G GP G PPG G++G +G G PG+PG PGP G PG QT+ Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-----QTI-----------T 660 Query: 451 EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 + GL G+ G G G PG G GQ G PG P +KGE G G G+ G G KG PG Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPG 719 Query: 511 DPGPPGLIGSPG---LKGQQGSAGSMGPRGPPGDV--GLPGEHGIPGKQGIKGEKGDPG- 564 PGPPG G+PG L+G G G GP+G PG G PG G+PG +G G KGD G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 565 -GIIGPPG------LPGPKGEAGPPGKSLP-GEPGL-----DGNPGAPGPRGPKGERGLP 611 G GPPG LPGPKG+ GP G+ P G PGL G PG PG GP G+ GL Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 612 GVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG 671 G+ G GD GP G+ +PG G +G G PG GP G PG PG PG G G PG G+ G Sbjct: 840 GIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 672 LPGPPGDPIALPLLGDIGAL-LKNFCG-NCQASVPGL---KSNKGEEGGAGEPGKYDS-- 724 + GPPG P L + G G LK G Q +PG K +KGE G G PG D Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 + KG+ G G PGIPG GPKG Y G+PG+ G GL G PG+PG PGP G PGL Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKG------YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 785 MGRTGHPGPTGAKG---EKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKG-----GV 835 G+ G GP G KG + G GP G GPPGP G+P + G+ KG + Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073 Query: 836 NVPSYPGP---PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP 892 +P PGP PG PG G+PG G G GLPGL G PG KG G G PG G G Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 893 GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD------- 945 G GPPG PG PGE GPVG G PG GP G+ G G+DGIPG G G+PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 946 -------RGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN-----KGSMGS 993 G KG+ G GIPG+ G G +G+PG G G GP GPPG+ +G G+ Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 PG QGPPG PG+PG LP Sbjct: 1254 PGPQGPPGRPGLPGPEGPP-----------------------------GLPGNGGIKGEK 1284 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGE------RGEPGI-GLPGSPGLPGTSAL---- 1102 G PG PG GLPG GD GP G +G G +G+PG+ G+PG PG+ G S + Sbjct: 1285 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1344 Query: 1103 ---GLPGSPGAPGPQGPPGPSGR 1122 G PG G PGP G PGPSG+ Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQ 1367 Score = 637 bits (1642), Expect = 0.0 Identities = 408/957 (42%), Positives = 473/957 (49%), Gaps = 156/957 (16%) Query: 291 KGEAGLPGAPGSPGQ-------------KGHKGEPGENGLHGAPGFPGQKGEQGFEGSKG 337 KGE GL G PG PGQ KG +G PG+ G G PG G G G G KG Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKG 286 Query: 338 ETGEKGEQGEKGDPALAGLNGENG---LKGDLGPHGPPG---PKGEKGDTGPPGPPALP- 390 E GE+GE G++G P G NG+ G L GD G G PG KG+KGDTGPPGPP L Sbjct: 287 EKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI 346 Query: 391 ---------GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG-----PPGPPGIQGIHQ 436 G G G G PG++G+RG G GPPG PGPPG PPGPPG G Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406 Query: 437 TLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPK-------GQKGEPGEPFTKG 489 G ++ G GL G G GLPG PG GP + G PG P + G Sbjct: 407 QKG---DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 490 EKGDRGEPGVIGSQG----------VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP 539 +KG +GE GV G +G + G PG PG PGL G PG G G G G G Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK----SLPGEPGLDGN 595 G GLPG G PG G G KG+PG I+ PG+ G KGE G PG LPG PG DG Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Query: 596 PGAPGP------------RGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQG------PA 637 PG PGP RGP G GLPG+ G+ G +GP G G PG G +G Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643 Query: 638 GEPGIQGPRGLPGL----PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLK 693 G+PGI GP+G PG PG PG PGN PGRDG GLPG PG P L G G+ K Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGN---PGRDGDVGLPGDPGLPGQPGLPGIPGS--K 698 Query: 694 NFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSK--GE 751 G +PG KG G G PG + R G GP GPPG PG +G G G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG- 810 G PG+PG KG G +G G PG PGP G GL G G G G G+ G GPPG PG Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 811 ----PPGPPGIPFNERNGMSSLYKIKG--------GVNVPSYPGPPGPPGPKGDPGPVGE 858 PPGPPGIP G L+ I G G++VP PG G PG G PGP+G Sbjct: 819 GVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 859 PGAMGLPG---LEGFPGVKGDRG---PAGPPGIAGMSGKPGAPG---------PPGVPGE 903 PG+ GLPG GFPG KG+ G P GPPG G+ G+ G PG PG+PG Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 904 PGERGPVGDIGFPGPEGP-----------SGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 GE+G G+ G PGP GP G+PG+ G G+ G +G G PGD G G Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS 996 Query: 953 GDQGIPGDRGSQGERGKPGLTGM------KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIP 1006 G G+PG G +G G PG G+ KG IG MG PG +G G PG G PG PG P Sbjct: 997 GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056 Query: 1007 GIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPG 1066 G+P ++ +S + LP G PG PG G+ G Sbjct: 1057 GLPGQK------------------GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 1067 PPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 GDPG G G G +G+PG+ G PG+PG PG + G PG+PG PG GP G G Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Score = 629 bits (1622), Expect = e-180 Identities = 395/909 (43%), Positives = 451/909 (49%), Gaps = 99/909 (10%) Query: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGH-----------KGEPGENGLHGAPGF 323 LP K + I KGE G PG PG PG G+ G GE G+ G G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642 Query: 324 PGQKGEQGFEGSKGET----GEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG 379 PGQ G G +G G+T G+ G G G GL G+ GL G G G PG KGE G Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702 Query: 380 --DTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGP--------PGPPGPP 429 G PGPP G GI GP G PG G+ G G GPPG PGP PGPPGPP Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762 Query: 430 GIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP---- 485 G+ G LG ++ G G G G GLPG G VGP GQ G G P Sbjct: 763 GLPGFKGALGPKGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 486 -FTKGEKGDRGEPGVIGS---QGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPP 539 +G G G PG IG G+ GE GDPGPPGL G PG +G G G+ GP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGA 598 G GLPG+ G G G KGE G++GPPG PGP G G G L G+ GL G PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEM----GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933 Query: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTP 658 PGP G KG +G PG+ G PG + P +G G G G G PG+ GP+G GLPG PG P Sbjct: 934 PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993 Query: 659 GNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G G PG G PG G PG P L+G G LK G+ PG + +G G +G Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--LKGTIGD--MGFPGPQGVEGPPGPSGV 1049 Query: 719 PGKYDSMARKGDIGPRGPPGI-----PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIP 773 PG+ S G G +G PGI PG GPKG G GYPG PG KG G G+PG+P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 774 GAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGP---------PGIPFNE-RN 823 G PG G PGL G G PGP G KG G G PG PG PGP PG P + + Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 824 GMSSLYKIKGGVNVPSYP--GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG 881 G + G P P G PGPPG G G G+ G G+PG G PG KG+ G G Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 882 PPGIAGMSGKPGAPGP--PGVPGEPGERGPVGDIGFPGPEGPSGKP---GINGKDGIPGA 936 PG+ G G PG+PGP G G PG +GP G G PGPEGP G P GI G+ G PG Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQ 1289 Query: 937 QGIMGKP---GDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 G+ G P GD+GP G +G+ G PG G +G+ G PG+ G G GP G PG+ G G Sbjct: 1290 PGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE 1349 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 PG GPPG PG+PG ++ + P Sbjct: 1350 PGLIGPPGPPGLPGPSGQSI----------------------IIKGDAGPPGIPGQPGLK 1387 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPGAPG 1112 G PGP G GLPGP G PG G G G G G G PG PG PGT GL G PG G Sbjct: 1388 GLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDGPPGPDG 1445 Query: 1113 PQGPPGPSG 1121 QGPPGP G Sbjct: 1446 LQGPPGPPG 1454 Score = 617 bits (1591), Expect = e-176 Identities = 437/1134 (38%), Positives = 505/1134 (44%), Gaps = 324/1134 (28%) Query: 284 QCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKG 343 +C C KGE G G PG +GH G PG G G PG GQKG+ G G G G +G Sbjct: 37 KCDCSGIKGEKG---ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 344 EQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P GL G G G GP G PG G KG+ G PG P PG +QGP GPPG Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG---LQGPPGPPG 150 Query: 404 KEGQRGRRGK---TGPPGKPGPPGPPGPPGIQGIHQTLG-----------GYYNKDN--- 446 G +G G + PG G PG PGPPGIQG+ G G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 447 ----KGNDEHEAGGLKGDKGETGL---PGFPGSV-------------------------G 474 KGN G KG+KGE GL PG PG + G Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 475 PKGQKGEPGEP-FTKGEKGDRGEPGVIGSQGVKGE------PGDPGPPGLIGSPGLKGQQ 527 P G +G PG P KGEKG++GEPG G G GE PG PG PG G PG G++ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 528 GSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP-- 575 G G GP GPPG +G G G+PG G KGE+G P GI GPPGLPGP Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGLPGPPG 389 Query: 576 ------------------KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKG----------- 606 KG+ GPPG S+PG PGLDG PGAPG GP G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 607 --ERGLPGVHGSPGDIGPQG--------------------------------------IG 626 E G PG GSPGD G QG +G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 627 IP------GRTGAQGPAGEPGIQGPRGLPGLPGT-------------------------P 655 P G+ GA GP G PGI G G PG PG+ P Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 656 GTPGNDGVPGRDGKPGLP---------------GPPGDPIALPLLGDIGAL--------- 691 G PG G PG+DG PGLP GPPG+P L G+IG + Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 692 ------LKNFCGN-CQASVPGLKSNKGEE-GGAGEPGKYDSMARKGDIGPRGPPGIPGR- 742 ++ GN Q +PG K + G+ G+PG + R GD+G G PG+PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 743 --EGPKGSKGERGYPGI--PGEKGDEGLQGIPGIPGAP---------GPTGPPGLMGRTG 789 G GSKGE G PGI PG G +G GIPG PGAP GP GPPG G G Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 790 H--------PGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNERNGMSSLYKIKGGVNVP 838 PGP G G KG+ GP G PGPPGPPG R G+ L KG V Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPKGDVGPN 804 Query: 839 SYPGPPGPP-----GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGP-----AGPPGIAGM 888 PGP GPP G +G PGP G PG +G PGL G PG KGD GP GPPG G Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 889 SGKPGAPGP------PGVPGE------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 G PGAPGP PG+PG+ PG +G +G +G PGP GP G PG +G G+ G Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 937 QGIMGKPGDRGPKGERGDQGIPG-----------DRGSQGERGKPGLTGMKGAIGPM--- 982 G+ G+PG GP GE+G +G PG GS+GE+G+PGL G+ G GP Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 983 ---GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G PG GPPG G PG+P + I + + Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG--------------QPGLIGPPGLKGTIG 1030 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGE--------------RGE 1085 + P G GPPG G+PG PG PG G +G KG+ +GE Sbjct: 1031 DMGFPGPQ------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1086 PG-------------IGLPGSPGLPGT-SALGLPGSPGAPGPQGPPGPSGRCNP 1125 PG +G PG PGLPGT A G PG PG PG GPPGP G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 615 bits (1585), Expect = e-175 Identities = 412/981 (41%), Positives = 469/981 (47%), Gaps = 194/981 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KG+ G+PG PG G +G G PG G G PG PG G G +G G G KGE+G G Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136 Query: 351 PALAGLNGENGLKGDLGPHGPPG---------PKGEKGDTGPPGPPALPGSLGIQGPQGP 401 P GL G G G G G PG PKG G GPPG LPG GI GP GP Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196 Query: 402 PGKEGQRGRRGKTGPPGKPGPPG--------PPGPPGIQGIHQTLG--GYYNKDNKGND- 450 PG G G GPPG PGP G P G G QG+ G G ++ + D Sbjct: 197 PGPPGLMG---PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDV 253 Query: 451 EHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE 508 E + G GL GD+G G PG G GP G GE GE +GE G RG+PG G G G Sbjct: 254 EFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 509 PGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKG 558 PG PG PG G PG G++G G GP GPPG +G G G+PG G KG Sbjct: 312 PGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Query: 559 EKGDPGGIIGPPGLPGP--------------------KGEAGPPGKSLPGEPGLDGNPGA 598 E+G PG I GPPGLPGP KG+ GPPG S+PG PGLDG PGA Sbjct: 372 ERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430 Query: 599 PGPRGPKG-------------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEP----- 640 PG GP G E G PG GSPGD G QG G +G G+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG-----EQGVKGDKGDTCFNCI 485 Query: 641 --GIQGPRGLPGLPGTPGTPGNDGVPGRDGK------------PGLPGPPGDPIALPLLG 686 GI GP G PGLPG PG PG+ G PG+ G+ PG+PG PG P G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG---------------------KYDSM 725 + G +L + PG+K +KGE G G PG + + Sbjct: 546 EPGDIL---------TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGY--PGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 KG+ GP G PG+PG G G G G+ PG GEKG +G+ G PG PG PGP G PG Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 784 LM----GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G+ G PG G G+ G G PG PG PG PGIP + KG +P Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS-----------KGEPGIPG 705 Query: 840 YPGPPGPPGPKGDPGPVGEPGAMGLPG---LEGFPGVKGDRGPAGPPGIAGMSGKPGAPG 896 G PGPPGPKG PG G PGA G PG LEG PG G GP G PG A PG PG Sbjct: 706 I-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA----LPGPPG 760 Query: 897 PPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD-- 954 PPG+PG G GP GD GFPGP GP G+ G++G G G G G+PG GP G G Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGV 820 Query: 955 QGIPGDRGSQGERGKPGLTGM---KGAIGPMG-----PPGNKGSMGSPGHQGPPGSPGIP 1006 QG PG G G G+PGL G+ KG GP G PPG +GS G PG GP G PG P Sbjct: 821 QGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880 Query: 1007 GIP--ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 G+P A A F K + + P + G PG G DGL Sbjct: 881 GLPGKAGASGFPGTKGEMGM-------------MGPPGPPGPLGIPGRSGVPGLKGDDGL 927 Query: 1065 PGPPGDPGPQGYRGQKGERGEPG---------------IGLPGSPGLPGTSA----LGLP 1105 G PG PGP G +G KGE G PG G PG PG+PG S GLP Sbjct: 928 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987 Query: 1106 GSPGAPGPQGPPGPSGRCNPE 1126 G PG PG G PG G P+ Sbjct: 988 GDPGQPGLSGQPGLPGPPGPK 1008 Score = 597 bits (1538), Expect = e-170 Identities = 372/874 (42%), Positives = 423/874 (48%), Gaps = 123/874 (14%) Query: 283 DQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS--KGETG 340 D Q I G+ GLPG PG G G G+PG G G PG PG KGE G G G G Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713 Query: 341 EKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPGSLGIQGP 398 KG G G P G G GL+G GP G PGPKGE G GPPGPP LPG G GP Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773 Query: 399 QG------PPGKEGQRGRRGKTGPPGKPGP---PGPPGPPGIQGIHQTLGGYYNKDNKGN 449 +G PPG G+ G G GP G GP PGP GPPG+ GI Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI--------------- 818 Query: 450 DEHEAGGLKGDKGETGLPG---FPGSVGPKGQKGEPGEPF--TKGEKGDRGEPGVIGSQG 504 G++G G G+PG PG G G+KG+PG P G G+RG PG+ G+ G Sbjct: 819 ------GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872 Query: 505 VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 G PG PG PG G+ G G +G G MGP GPPG +G+PG G+PG +G G +G PG Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932 Query: 565 --------GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGS 616 G G PGLPGP G P GE G G PG PG GPKG +GLPG G Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992 Query: 617 PGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 PG G G+ G PG G G G+PG+ GP GL G G G PG GV G G G+PG Sbjct: 993 PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 PG P GD K G +PGL KGE G G PG + KG +G G Sbjct: 1053 PGSPGLPGQKGD-----KGDPGISSIGLPGLPGPKGEPGLPGYPG---NPGIKGSVGDPG 1104 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 PG+PG G KG G G+PG PG G +G+ G PG PG PG GP G G G PGP G Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 796 AKGEKGSDG---PPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD 852 KG+ G DG P G+ G PG PG G+ L KG +P PG PG PGPKG+ Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 853 PGPVGEPGAMGLPGLEGFPGV-----KGDRGPAGPPGIAGMSGKPGAPG----------- 896 PG G PG G PG G PG KG+ GP GPPG G+ G G PG Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEK 1284 Query: 897 -PPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ 955 PG PG PG G GD G PG +G G+PG+NG G PG G+ G PG +GP G G Sbjct: 1285 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1344 Query: 956 GIPGDRGSQGERGKPGLTG-------MKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGI 1008 G G+ G G G PGL G +KG GP G PG G G PG QGP G PG G Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP 1404 Query: 1009 PADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPP 1068 P D + LP A G PG PG+ G G Sbjct: 1405 PGDP--------------------------GRNGLPGFDGAGGRKGDPGLPGQPGTRGLD 1438 Query: 1069 GDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSAL 1102 G PGP GL G PG PGTS++ Sbjct: 1439 GPPGPD--------------GLQGPPGPPGTSSV 1458 Score = 489 bits (1260), Expect = e-138 Identities = 341/833 (40%), Positives = 389/833 (46%), Gaps = 126/833 (15%) Query: 401 PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA-GGLKG 459 P K G +G+ G G PG G PG PG G G + KG+D G KG Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKG 90 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIG 519 +G GLPGFPG+ G G G G P +G G G G G G G PG GPPG G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 520 SPGLKGQQGS---AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPG 571 PG+KG+ GS + GP+G PG G PG G+PG GI G G PG G GPPG Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 572 LPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRG-------------PKGERGLPGVHGSPG 618 LPGPKG G + GE G G G PGP G KG++GLPG G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 619 DIGPQG--------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP 670 G +G G G G G G+PG G G PG+PG PG PG G PGRDG+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 671 GL------PGPPGDPIALPLLG-DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 G PGPPG I P G IG GN +PGL KGE G G G Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEK-----GN--IGLPGLPGEKGERGFPGIQGPPG 383 Query: 724 SMARKGD--IGPRGPPGIPGREGPKGSKGERG--YPGIPGEKGDEGLQGIPGIPG----- 774 G +GP GPPG PG G KG +G G PG PG G G G+PG PG Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 775 --------APGPTGPPGLMGRTGHPGPTGAKGEKGS----------DGPPGKPGPPGPPG 816 PGP GPPG G G G G KG+KG GPPG+PG PG PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 817 IPFN-------ERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV------------- 856 P + G + KG +P PG PG PG KG+PG + Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 857 GEPGAMGLPGLEGFP---GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDI 913 G PGA GLPGL G P G+ G GP G PG G+ G PG PG+PG PG GP+G Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPP 623 Query: 914 GFPGPEGPSGKPGINGKDGIPGAQGI-------------MGKPGDRGPKGERGDQGIPGD 960 GF GP GP G+ GI G G PG GI GKPG G G GD G+PGD Sbjct: 624 GF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 961 RGSQGERGKPGLTGMKG-----AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGI--PADAV 1013 G G+ G PG+ G KG IG GPPG KG G PG G PG+PG G+ P Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 1014 SFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY-GRPGPPGK---DGLPGPPG 1069 F K + + L K + + G PGPPG+ DGLPGP G Sbjct: 743 GFPGPK---GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPG-TSALGLPGSPGAPGPQGPPGPSG 1121 D GP G G G G PGIG+ G PG PG +G PG G PG +G PGP G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 298 bits (764), Expect = 2e-80 Identities = 189/455 (41%), Positives = 220/455 (48%), Gaps = 75/455 (16%) Query: 715 GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGL-------- 766 G K D KG+ G RG PG+ G G G G G PG G+KGD+G+ Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 767 -QGIPGIPGAPGPTGPPGLMGRTGHPGP------TGAKGEKGSDGPPGKP---GPPGPPG 816 +G PG+PG PG G PG+ G G PGP G KGE+G G PG P GPPGPPG Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 817 IP-FNERNGMSSLYKIKGGVNVPSYPGPP---GPPGPKGDPGPV---GEPGAMGLPGLEG 869 IP G + + G P YPGPP G PGP G PGP+ G PG MG PG G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 870 FPGVKGDRGP--AGPPGIAGMSGKPGAPGPPGVPGEPGERGPV------GDIGFPGPEGP 921 PG KG+ G GP G G G G PGPPG E ++ P+ GD G PG GP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE--QKRPIDVEFQKGDQGLPGDRGP 268 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 G PGI G G PG G++G KGE+G+ G G G GE G+PG+ G+ G G Sbjct: 269 PGPPGIRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320 Query: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 G PG G G G GPPG PG+ IP +K + Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGTGITIGEK------------------GNI 361 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPP-----GDPGPQGY---RGQKGERGEPGIGLPGS 1093 LP G PG G GLPGPP G PGP G+ RGQKG+ G PGI +PG Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 1094 PGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 PGL G PG+PG PGP GP GP + E C Sbjct: 422 PGLDGQ-----PGAPGLPGPPGPAGPHIPPSDEIC 451 Score = 107 bits (266), Expect = 8e-23 Identities = 72/203 (35%), Positives = 81/203 (39%), Gaps = 67/203 (33%) Query: 947 GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH------QGPP 1000 G KGE+G++G PG G PGL G G GP GP G KG G PG +GPP Sbjct: 42 GIKGEKGERGFPG------LEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPG 1060 G PG PG P G PG PG Sbjct: 96 GLPGFPGTP--------------------------------------------GLPGMPG 111 Query: 1061 KDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-------LGLPGSPG 1109 DG PGP G PG G +G++G G PG G PG PG+PG LPG G Sbjct: 112 HDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171 Query: 1110 APGPQGPPGPSGRCNPEDCLYPV 1132 PG GPPG G P P+ Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPI 194 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 652 bits (1681), Expect = 0.0 Identities = 418/1005 (41%), Positives = 481/1005 (47%), Gaps = 217/1005 (21%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG---- 346 KGE G PG G PG+ G G+PG GL G PG+PG+ G G +G KG+TG G G Sbjct: 288 KGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIP 347 Query: 347 ---------EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPGSLGI 395 EKG+ L GL GE G +G G GPPG G G GPPGPP PG G Sbjct: 348 RPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQ 407 Query: 396 QGPQGPPG--------KEGQRGRRGKTGPPGKPGP----------PGPPGPPGIQGIHQT 437 +G +GPPG +GQ G G GPPG GP PGPPGPPG G Sbjct: 408 KGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL 467 Query: 438 LGGYYNKDNKGNDEHEA--GGLKGDKGETGLPGFPG------------------SVGPKG 477 G K +KG+ G+ G G+ GLPG PG + GPKG Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 478 QKGEPGEPFTKGEKGDRGEPGVI----GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSM 533 G PG P G G +GEPG I G +G KGE G PG PGL G PG GQ G G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLP 587 Query: 534 GPRGPPGDVGLPGEHGIPGKQGIKG--------------------EKGDPG--GIIGPPG 571 GP+G PG + GE G PG G+ G EKG G G G PG Sbjct: 588 GPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG 647 Query: 572 LPGPKGEAGP----PGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIG 626 +PGPKG+ G PGK LPG PG DG+ G PG G G+ GLPG+ GS G+ G GIG Sbjct: 648 IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707 Query: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPG--LPGPPGDPIA 681 +PG GP G PGI GP G PG PG G PG G PG G+PG LPGPPG P Sbjct: 708 LPG---PPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL 764 Query: 682 LPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPG 741 G +G PG G G G PG + G GP GPPG+PG Sbjct: 765 PGFKGALGP-------KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 742 -----REGPKGSKGERGYPG---IPGEKGDEGLQGI-----------PGIPGAPGPTGPP 782 GP G G G PG IPGEKGD G G+ PGIPGAPGP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 783 GLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 G G G G +G G KG G G PGPPGP GIP R+G+ L G P PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIP--GRSGVPGLKGDDGLQGQPGLPG 935 Query: 843 PPGPPGPKGDPGPVGEPGAM--------------GLPGLEGFPGVKGDRGPAGPPGIAGM 888 P G G KG+PG G PG M GLPG+ G G KG +G G PG G+ Sbjct: 936 PTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGL 995 Query: 889 SGKPGAPGPPG------VPGEPGERGP------VGDIGFPGPEGPSGKPGINGKDGIPGA 936 SG+PG PGPPG +PG+PG GP +GD+GFPGP+G G PG +G G PG+ Sbjct: 996 SGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGS 1055 Query: 937 QGIMGKPGDRG--------------PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982 G+ G+ GD+G PKGE G G PG+ G +G G PGL G+ G G Sbjct: 1056 PGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAK 1115 Query: 983 GPPGNKGSMGSPGHQGPPG---SPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G+PG GP G PG PG+P + Sbjct: 1116 GQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE---------------------------- 1147 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGT 1099 P + G+PGPPG+ G PG G PGP G QKGE G+PG G PG PGLPG Sbjct: 1148 ----PGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG---QKGEPGQPGFGNPGPPGLPGL 1200 Query: 1100 SAL-------GLPGSPGAPGP------------QGPPGPSGRCNP 1125 S G+PG+PG PGP QGPPGP G P Sbjct: 1201 SGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Score = 642 bits (1655), Expect = 0.0 Identities = 409/923 (44%), Positives = 474/923 (51%), Gaps = 141/923 (15%) Query: 292 GEAGLPGAPGS---PGQKGHKGE---------PGENGLHGAPGFPGQKGEQG----FEGS 335 G GLPG PGS PGQKG KG+ PG G GAPGFPG KGE G F G Sbjct: 497 GLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGS 392 KG+ GE G G G P L G G++GL G GP G PG KGE+G G PG P LPG+ Sbjct: 557 KGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGN 616 Query: 393 LGIQGPQG--PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450 +G GP G PPG G++G +G G PG+PG PGP G PG QT+ Sbjct: 617 IGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG-----QTI-----------T 660 Query: 451 EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 + GL G+ G G G PG G GQ G PG P +KGE G G G+ G G KG PG Sbjct: 661 QPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPKGFPG 719 Query: 511 DPGPPGLIGSPG---LKGQQGSAGSMGPRGPPGDV--GLPGEHGIPGKQGIKGEKGDPG- 564 PGPPG G+PG L+G G G GP+G PG G PG G+PG +G G KGD G Sbjct: 720 IPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGF 779 Query: 565 -GIIGPPG------LPGPKGEAGPPGKSLP-GEPGL-----DGNPGAPGPRGPKGERGLP 611 G GPPG LPGPKG+ GP G+ P G PGL G PG PG GP G+ GL Sbjct: 780 PGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLH 839 Query: 612 GVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG 671 G+ G GD GP G+ +PG G +G G PG GP G PG PG PG G G PG G+ G Sbjct: 840 GIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMG 899 Query: 672 LPGPPGDPIALPLLGDIGAL-LKNFCG-NCQASVPGL---KSNKGEEGGAGEPGKYDS-- 724 + GPPG P L + G G LK G Q +PG K +KGE G G PG D Sbjct: 900 MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL 959 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 + KG+ G G PGIPG GPKG Y G+PG+ G GL G PG+PG PGP G PGL Sbjct: 960 LGSKGEKGEPGLPGIPGVSGPKG------YQGLPGDPGQPGLSGQPGLPGPPGPKGNPGL 1013 Query: 785 MGRTGHPGPTGAKG---EKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKG-----GV 835 G+ G GP G KG + G GP G GPPGP G+P + G+ KG + Sbjct: 1014 PGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSI 1073 Query: 836 NVPSYPGP---PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP 892 +P PGP PG PG G+PG G G GLPGL G PG KG G G PG G G Sbjct: 1074 GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPK 1133 Query: 893 GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD------- 945 G GPPG PG PGE GPVG G PG GP G+ G G+DGIPG G G+PG Sbjct: 1134 GISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPG 1193 Query: 946 -------RGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN-----KGSMGS 993 G KG+ G GIPG+ G G +G+PG G G GP GPPG+ +G G+ Sbjct: 1194 PPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGN 1253 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 PG QGPPG PG G+P LP Sbjct: 1254 PGPQGPPGRPGFQGLPGPE--------------------------GPPGLPGNGGIKGEK 1287 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGE------RGEPGI-GLPGSPGLPGTSAL---- 1102 G PG PG GLPG GD GP G +G G +G+PG+ G+PG PG+ G S + Sbjct: 1288 GNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSA 1347 Query: 1103 ---GLPGSPGAPGPQGPPGPSGR 1122 G PG G PGP G PGPSG+ Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQ 1370 Score = 637 bits (1642), Expect = 0.0 Identities = 408/957 (42%), Positives = 473/957 (49%), Gaps = 156/957 (16%) Query: 291 KGEAGLPGAPGSPGQ-------------KGHKGEPGENGLHGAPGFPGQKGEQGFEGSKG 337 KGE GL G PG PGQ KG +G PG+ G G PG G G G G KG Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKG 286 Query: 338 ETGEKGEQGEKGDPALAGLNGENG---LKGDLGPHGPPG---PKGEKGDTGPPGPPALP- 390 E GE+GE G++G P G NG+ G L GD G G PG KG+KGDTGPPGPP L Sbjct: 287 EKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVI 346 Query: 391 ---------GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG-----PPGPPGIQGIHQ 436 G G G G PG++G+RG G GPPG PGPPG PPGPPG G Sbjct: 347 PRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERG 406 Query: 437 TLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPK-------GQKGEPGEPFTKG 489 G ++ G GL G G GLPG PG GP + G PG P + G Sbjct: 407 QKG---DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 490 EKGDRGEPGVIGSQG----------VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP 539 +KG +GE GV G +G + G PG PG PGL G PG G G G G G Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK----SLPGEPGLDGN 595 G GLPG G PG G G KG+PG I+ PG+ G KGE G PG LPG PG DG Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGL 583 Query: 596 PGAPGP------------RGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQG------PA 637 PG PGP RGP G GLPG+ G+ G +GP G G PG G +G Sbjct: 584 PGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNP 643 Query: 638 GEPGIQGPRGLPGL----PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLK 693 G+PGI GP+G PG PG PG PGN PGRDG GLPG PG P L G G+ K Sbjct: 644 GQPGIPGPKGDPGQTITQPGKPGLPGN---PGRDGDVGLPGDPGLPGQPGLPGIPGS--K 698 Query: 694 NFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSK--GE 751 G +PG KG G G PG + R G GP GPPG PG +G G G Sbjct: 699 GEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGP 758 Query: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG- 810 G PG+PG KG G +G G PG PGP G GL G G G G G+ G GPPG PG Sbjct: 759 PGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI 818 Query: 811 ----PPGPPGIPFNERNGMSSLYKIKG--------GVNVPSYPGPPGPPGPKGDPGPVGE 858 PPGPPGIP G L+ I G G++VP PG G PG G PGP+G Sbjct: 819 GVQGPPGPPGIP--GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGP 876 Query: 859 PGAMGLPG---LEGFPGVKGDRG---PAGPPGIAGMSGKPGAPG---------PPGVPGE 903 PG+ GLPG GFPG KG+ G P GPPG G+ G+ G PG PG+PG Sbjct: 877 PGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGP 936 Query: 904 PGERGPVGDIGFPGPEGP-----------SGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 GE+G G+ G PGP GP G+PG+ G G+ G +G G PGD G G Sbjct: 937 TGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLS 996 Query: 953 GDQGIPGDRGSQGERGKPGLTGM------KGAIGPMGPPGNKGSMGSPGHQGPPGSPGIP 1006 G G+PG G +G G PG G+ KG IG MG PG +G G PG G PG PG P Sbjct: 997 GQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSP 1056 Query: 1007 GIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPG 1066 G+P ++ +S + LP G PG PG G+ G Sbjct: 1057 GLPGQK------------------GDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098 Query: 1067 PPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 GDPG G G G +G+PG+ G PG+PG PG + G PG+PG PG GP G G Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGG 1155 Score = 626 bits (1614), Expect = e-179 Identities = 396/912 (43%), Positives = 452/912 (49%), Gaps = 102/912 (11%) Query: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGH-----------KGEPGENGLHGAPGF 323 LP K + I KGE G PG PG PG G+ G GE G+ G G Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642 Query: 324 PGQKGEQGFEGSKGET----GEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG 379 PGQ G G +G G+T G+ G G G GL G+ GL G G G PG KGE G Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPG 702 Query: 380 --DTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGP--------PGPPGPP 429 G PGPP G GI GP G PG G+ G G GPPG PGP PGPPGPP Sbjct: 703 IPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPP 762 Query: 430 GIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP---- 485 G+ G LG ++ G G G G GLPG G VGP GQ G G P Sbjct: 763 GLPGFKGALGPKGDRGFPG-----PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPG 817 Query: 486 -FTKGEKGDRGEPGVIGS---QGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPP 539 +G G G PG IG G+ GE GDPGPPGL G PG +G G G+ GP GPP Sbjct: 818 IGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP 877 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGA 598 G GLPG+ G G G KGE G++GPPG PGP G G G L G+ GL G PG Sbjct: 878 GSPGLPGKAGASGFPGTKGEM----GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGL 933 Query: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTP 658 PGP G KG +G PG+ G PG + P +G G G G G PG+ GP+G GLPG PG P Sbjct: 934 PGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQP 993 Query: 659 GNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G G PG G PG G PG P L+G G LK G+ PG + +G G +G Sbjct: 994 GLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG--LKGTIGD--MGFPGPQGVEGPPGPSGV 1049 Query: 719 PGKYDSMARKGDIGPRGPPGI-----PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIP 773 PG+ S G G +G PGI PG GPKG G GYPG PG KG G G+PG+P Sbjct: 1050 PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLP 1109 Query: 774 GAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGP---------PGIPFNE-RN 823 G PG G PGL G G PGP G KG G G PG PG PGP PG P + + Sbjct: 1110 GTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKP 1169 Query: 824 GMSSLYKIKGGVNVPSYP--GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG 881 G + G P P G PGPPG G G G+ G G+PG G PG KG+ G G Sbjct: 1170 GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHG 1229 Query: 882 PPGIAGMSGKPGAPGP--PGVPGEPGERGPVGDIGF---PGPEGPSGKP---GINGKDGI 933 PG+ G G PG+PGP G G PG +GP G GF PGPEGP G P GI G+ G Sbjct: 1230 FPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGN 1289 Query: 934 PGAQGIMGKP---GDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGS 990 PG G+ G P GD+GP G +G+ G PG G +G+ G PG+ G G GP G PG+ G Sbjct: 1290 PGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGP 1349 Query: 991 MGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAA 1050 G PG GPPG PG+PG ++ + P Sbjct: 1350 EGEPGLIGPPGPPGLPGPSGQSI----------------------IIKGDAGPPGIPGQP 1387 Query: 1051 QAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPG 1109 G PGP G GLPGP G PG G G G G G G PG PG PGT GL G PG Sbjct: 1388 GLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR--GLDGPPG 1445 Query: 1110 APGPQGPPGPSG 1121 G QGPPGP G Sbjct: 1446 PDGLQGPPGPPG 1457 Score = 617 bits (1591), Expect = e-176 Identities = 437/1134 (38%), Positives = 505/1134 (44%), Gaps = 324/1134 (28%) Query: 284 QCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKG 343 +C C KGE G G PG +GH G PG G G PG GQKG+ G G G G +G Sbjct: 37 KCDCSGIKGEKG---ERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRG 93 Query: 344 EQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P GL G G G GP G PG G KG+ G PG P PG +QGP GPPG Sbjct: 94 PPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPG---LQGPPGPPG 150 Query: 404 KEGQRGRRGK---TGPPGKPGPPGPPGPPGIQGIHQTLG-----------GYYNKDN--- 446 G +G G + PG G PG PGPPGIQG+ G G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 447 ----KGNDEHEAGGLKGDKGETGL---PGFPGSV-------------------------G 474 KGN G KG+KGE GL PG PG + G Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 475 PKGQKGEPGEP-FTKGEKGDRGEPGVIGSQGVKGE------PGDPGPPGLIGSPGLKGQQ 527 P G +G PG P KGEKG++GEPG G G GE PG PG PG G PG G++ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 528 GSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP-- 575 G G GP GPPG +G G G+PG G KGE+G P GI GPPGLPGP Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFP-GIQGPPGLPGPPG 389 Query: 576 ------------------KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKG----------- 606 KG+ GPPG S+PG PGLDG PGAPG GP G Sbjct: 390 AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDE 449 Query: 607 --ERGLPGVHGSPGDIGPQG--------------------------------------IG 626 E G PG GSPGD G QG +G Sbjct: 450 ICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLG 509 Query: 627 IP------GRTGAQGPAGEPGIQGPRGLPGLPGT-------------------------P 655 P G+ GA GP G PGI G G PG PG+ P Sbjct: 510 FPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAP 569 Query: 656 GTPGNDGVPGRDGKPGLP---------------GPPGDPIALPLLGDIGAL--------- 691 G PG G PG+DG PGLP GPPG+P L G+IG + Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG 629 Query: 692 ------LKNFCGN-CQASVPGLKSNKGEE-GGAGEPGKYDSMARKGDIGPRGPPGIPGR- 742 ++ GN Q +PG K + G+ G+PG + R GD+G G PG+PG+ Sbjct: 630 PVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQP 689 Query: 743 --EGPKGSKGERGYPGI--PGEKGDEGLQGIPGIPGAP---------GPTGPPGLMGRTG 789 G GSKGE G PGI PG G +G GIPG PGAP GP GPPG G G Sbjct: 690 GLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKG 749 Query: 790 H--------PGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNERNGMSSLYKIKGGVNVP 838 PGP G G KG+ GP G PGPPGPPG R G+ L KG V Sbjct: 750 EPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPKGDVGPN 804 Query: 839 SYPGPPGPP-----GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGP-----AGPPGIAGM 888 PGP GPP G +G PGP G PG +G PGL G PG KGD GP GPPG G Sbjct: 805 GQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGS 864 Query: 889 SGKPGAPGP------PGVPGE------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 G PGAPGP PG+PG+ PG +G +G +G PGP GP G PG +G G+ G Sbjct: 865 PGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGD 924 Query: 937 QGIMGKPGDRGPKGERGDQGIPG-----------DRGSQGERGKPGLTGMKGAIGPM--- 982 G+ G+PG GP GE+G +G PG GS+GE+G+PGL G+ G GP Sbjct: 925 DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQ 984 Query: 983 ---GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 G PG G G PG GPPG G PG+P + I + + Sbjct: 985 GLPGDPGQPGLSGQPGLPGPPGPKGNPGLPG--------------QPGLIGPPGLKGTIG 1030 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGE--------------RGE 1085 + P G GPPG G+PG PG PG G +G KG+ +GE Sbjct: 1031 DMGFPGPQ------GVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1086 PG-------------IGLPGSPGLPGT-SALGLPGSPGAPGPQGPPGPSGRCNP 1125 PG +G PG PGLPGT A G PG PG PG GPPGP G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGP 1138 Score = 615 bits (1585), Expect = e-175 Identities = 412/981 (41%), Positives = 469/981 (47%), Gaps = 194/981 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KG+ G+PG PG G +G G PG G G PG PG G G +G G G KGE+G G Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGS 136 Query: 351 PALAGLNGENGLKGDLGPHGPPG---------PKGEKGDTGPPGPPALPGSLGIQGPQGP 401 P GL G G G G G PG PKG G GPPG LPG GI GP GP Sbjct: 137 PGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGP 196 Query: 402 PGKEGQRGRRGKTGPPGKPGPPG--------PPGPPGIQGIHQTLG--GYYNKDNKGND- 450 PG G G GPPG PGP G P G G QG+ G G ++ + D Sbjct: 197 PGPPGLMG---PPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDV 253 Query: 451 EHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE 508 E + G GL GD+G G PG G GP G GE GE +GE G RG+PG G G G Sbjct: 254 EFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 509 PGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG----------DVGLPGEHGIPGKQGIKG 558 PG PG PG G PG G++G G GP GPPG +G G G+PG G KG Sbjct: 312 PGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKG 371 Query: 559 EKGDPGGIIGPPGLPGP--------------------KGEAGPPGKSLPGEPGLDGNPGA 598 E+G PG I GPPGLPGP KG+ GPPG S+PG PGLDG PGA Sbjct: 372 ERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGA 430 Query: 599 PGPRGPKG-------------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEP----- 640 PG GP G E G PG GSPGD G QG G +G G+ Sbjct: 431 PGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG-----EQGVKGDKGDTCFNCI 485 Query: 641 --GIQGPRGLPGLPGTPGTPGNDGVPGRDGK------------PGLPGPPGDPIALPLLG 686 GI GP G PGLPG PG PG+ G PG+ G+ PG+PG PG P G Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG---------------------KYDSM 725 + G +L + PG+K +KGE G G PG + + Sbjct: 546 EPGDIL---------TFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGI 596 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGY--PGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 KG+ GP G PG+PG G G G G+ PG GEKG +G+ G PG PG PGP G PG Sbjct: 597 TFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPG 656 Query: 784 LM----GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G+ G PG G G+ G G PG PG PG PGIP + KG +P Sbjct: 657 QTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS-----------KGEPGIPG 705 Query: 840 YPGPPGPPGPKGDPGPVGEPGAMGLPG---LEGFPGVKGDRGPAGPPGIAGMSGKPGAPG 896 G PGPPGPKG PG G PGA G PG LEG PG G GP G PG A PG PG Sbjct: 706 I-GLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFA----LPGPPG 760 Query: 897 PPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD-- 954 PPG+PG G GP GD GFPGP GP G+ G++G G G G G+PG GP G G Sbjct: 761 PPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGV 820 Query: 955 QGIPGDRGSQGERGKPGLTGM---KGAIGPMG-----PPGNKGSMGSPGHQGPPGSPGIP 1006 QG PG G G G+PGL G+ KG GP G PPG +GS G PG GP G PG P Sbjct: 821 QGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSP 880 Query: 1007 GIP--ADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 G+P A A F K + + P + G PG G DGL Sbjct: 881 GLPGKAGASGFPGTKGEMGM-------------MGPPGPPGPLGIPGRSGVPGLKGDDGL 927 Query: 1065 PGPPGDPGPQGYRGQKGERGEPG---------------IGLPGSPGLPGTSA----LGLP 1105 G PG PGP G +G KGE G PG G PG PG+PG S GLP Sbjct: 928 QGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLP 987 Query: 1106 GSPGAPGPQGPPGPSGRCNPE 1126 G PG PG G PG G P+ Sbjct: 988 GDPGQPGLSGQPGLPGPPGPK 1008 Score = 600 bits (1548), Expect = e-171 Identities = 373/877 (42%), Positives = 424/877 (48%), Gaps = 126/877 (14%) Query: 283 DQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS--KGETG 340 D Q I G+ GLPG PG G G G+PG G G PG PG KGE G G G G Sbjct: 654 DPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPG 713 Query: 341 EKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT--GPPGPPALPGSLGIQGP 398 KG G G P G G GL+G GP G PGPKGE G GPPGPP LPG G GP Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773 Query: 399 QG------PPGKEGQRGRRGKTGPPGKPGP---PGPPGPPGIQGIHQTLGGYYNKDNKGN 449 +G PPG G+ G G GP G GP PGP GPPG+ GI Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI--------------- 818 Query: 450 DEHEAGGLKGDKGETGLPG---FPGSVGPKGQKGEPGEPF--TKGEKGDRGEPGVIGSQG 504 G++G G G+PG PG G G+KG+PG P G G+RG PG+ G+ G Sbjct: 819 ------GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPG 872 Query: 505 VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 G PG PG PG G+ G G +G G MGP GPPG +G+PG G+PG +G G +G PG Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPG 932 Query: 565 --------GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGS 616 G G PGLPGP G P GE G G PG PG GPKG +GLPG G Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQ 992 Query: 617 PGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 PG G G+ G PG G G G+PG+ GP GL G G G PG GV G G G+PG Sbjct: 993 PGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQ 1052 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 PG P GD K G +PGL KGE G G PG + KG +G G Sbjct: 1053 PGSPGLPGQKGD-----KGDPGISSIGLPGLPGPKGEPGLPGYPG---NPGIKGSVGDPG 1104 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 PG+PG G KG G G+PG PG G +G+ G PG PG PG GP G G G PGP G Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164 Query: 796 AKGEKGSDG---PPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD 852 KG+ G DG P G+ G PG PG G+ L KG +P PG PG PGPKG+ Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224 Query: 853 PGPVGEPGAMGLPGLEGFPGV-----KGDRGPAGPPGIAGMSGKPGAPGPPGVPGE---- 903 PG G PG G PG G PG KG+ GP GPPG G G PG GPPG+PG Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIK 1284 Query: 904 -----------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 PG G GD G PG +G G+PG+NG G PG G+ G PG +GP G Sbjct: 1285 GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP 1344 Query: 953 GDQGIPGDRGSQGERGKPGLTG-------MKGAIGPMGPPGNKGSMGSPGHQGPPGSPGI 1005 G G G+ G G G PGL G +KG GP G PG G G PG QGP G PG Sbjct: 1345 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGP 1404 Query: 1006 PGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLP 1065 G P D + LP A G PG PG+ G Sbjct: 1405 TGPPGDP--------------------------GRNGLPGFDGAGGRKGDPGLPGQPGTR 1438 Query: 1066 GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSAL 1102 G G PGP GL G PG PGTS++ Sbjct: 1439 GLDGPPGPD--------------GLQGPPGPPGTSSV 1461 Score = 489 bits (1260), Expect = e-138 Identities = 341/833 (40%), Positives = 389/833 (46%), Gaps = 126/833 (15%) Query: 401 PPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA-GGLKG 459 P K G +G+ G G PG G PG PG G G + KG+D G KG Sbjct: 34 PGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPG---PRGQKGDDGIPGPPGPKG 90 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIG 519 +G GLPGFPG+ G G G G P +G G G G G G G PG GPPG G Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 520 SPGLKGQQGS---AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPG 571 PG+KG+ GS + GP+G PG G PG G+PG GI G G PG G GPPG Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 572 LPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRG-------------PKGERGLPGVHGSPG 618 LPGPKG G + GE G G G PGP G KG++GLPG G PG Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPG 270 Query: 619 DIGPQG--------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP 670 G +G G G G G G+PG G G PG+PG PG PG G PGRDG+ Sbjct: 271 PPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEK 330 Query: 671 GL------PGPPGDPIALPLLG-DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 G PGPPG I P G IG GN +PGL KGE G G G Sbjct: 331 GQKGDTGPPGPPGLVIPRPGTGITIGEK-----GN--IGLPGLPGEKGERGFPGIQGPPG 383 Query: 724 SMARKGD--IGPRGPPGIPGREGPKGSKGERG--YPGIPGEKGDEGLQGIPGIPG----- 774 G +GP GPPG PG G KG +G G PG PG G G G+PG PG Sbjct: 384 LPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPH 443 Query: 775 --------APGPTGPPGLMGRTGHPGPTGAKGEKGS----------DGPPGKPGPPGPPG 816 PGP GPPG G G G G KG+KG GPPG+PG PG PG Sbjct: 444 IPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPG 503 Query: 817 IPFN-------ERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV------------- 856 P + G + KG +P PG PG PG KG+PG + Sbjct: 504 PPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGEL 563 Query: 857 GEPGAMGLPGLEGFP---GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDI 913 G PGA GLPGL G P G+ G GP G PG G+ G PG PG+PG PG GP+G Sbjct: 564 GSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPP 623 Query: 914 GFPGPEGPSGKPGINGKDGIPGAQGI-------------MGKPGDRGPKGERGDQGIPGD 960 GF GP GP G+ GI G G PG GI GKPG G G GD G+PGD Sbjct: 624 GF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGD 682 Query: 961 RGSQGERGKPGLTGMKG-----AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGI--PADAV 1013 G G+ G PG+ G KG IG GPPG KG G PG G PG+PG G+ P Sbjct: 683 PGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPP 742 Query: 1014 SFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY-GRPGPPGK---DGLPGPPG 1069 F K + + L K + + G PGPPG+ DGLPGP G Sbjct: 743 GFPGPK---GEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKG 799 Query: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPG-TSALGLPGSPGAPGPQGPPGPSG 1121 D GP G G G G PGIG+ G PG PG +G PG G PG +G PGP G Sbjct: 800 DVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPG 852 Score = 298 bits (764), Expect = 2e-80 Identities = 189/455 (41%), Positives = 220/455 (48%), Gaps = 75/455 (16%) Query: 715 GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGL-------- 766 G K D KG+ G RG PG+ G G G G G PG G+KGD+G+ Sbjct: 31 GCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG 90 Query: 767 -QGIPGIPGAPGPTGPPGLMGRTGHPGP------TGAKGEKGSDGPPGKP---GPPGPPG 816 +G PG+PG PG G PG+ G G PGP G KGE+G G PG P GPPGPPG Sbjct: 91 IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPG 150 Query: 817 IP-FNERNGMSSLYKIKGGVNVPSYPGPP---GPPGPKGDPGPV---GEPGAMGLPGLEG 869 IP G + + G P YPGPP G PGP G PGP+ G PG MG PG G Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPG 210 Query: 870 FPGVKGDRGP--AGPPGIAGMSGKPGAPGPPGVPGEPGERGPV------GDIGFPGPEGP 921 PG KG+ G GP G G G G PGPPG E ++ P+ GD G PG GP Sbjct: 211 LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISE--QKRPIDVEFQKGDQGLPGDRGP 268 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 G PGI G G PG G++G KGE+G+ G G G GE G+PG+ G+ G G Sbjct: 269 PGPPGIRGPPGPPG--------GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGY 320 Query: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 G PG G G G GPPG PG+ IP +K + Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLV-IPRPGTGITIGEK------------------GNI 361 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPP-----GDPGPQGY---RGQKGERGEPGIGLPGS 1093 LP G PG G GLPGPP G PGP G+ RGQKG+ G PGI +PG Sbjct: 362 GLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGP 421 Query: 1094 PGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 PGL G PG+PG PGP GP GP + E C Sbjct: 422 PGLDGQ-----PGAPGLPGPPGPAGPHIPPSDEIC 451 Score = 107 bits (266), Expect = 8e-23 Identities = 72/203 (35%), Positives = 81/203 (39%), Gaps = 67/203 (33%) Query: 947 GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH------QGPP 1000 G KGE+G++G PG G PGL G G GP GP G KG G PG +GPP Sbjct: 42 GIKGEKGERGFPG------LEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPP 95 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPG 1060 G PG PG P G PG PG Sbjct: 96 GLPGFPGTP--------------------------------------------GLPGMPG 111 Query: 1061 KDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-------LGLPGSPG 1109 DG PGP G PG G +G++G G PG G PG PG+PG LPG G Sbjct: 112 HDGAPGPQGIPGCNGTKGERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171 Query: 1110 APGPQGPPGPSGRCNPEDCLYPV 1132 PG GPPG G P P+ Sbjct: 172 NPGYPGPPGIQGLPGPTGIPGPI 194 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 635 bits (1639), Expect = 0.0 Identities = 394/914 (43%), Positives = 440/914 (48%), Gaps = 130/914 (14%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G+ G G PG PG++G G PG G G PGFPG KG +GF+G GE GE G G KG+ Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGPPGPPAL---- 389 GL GENG G +GP G PG +G G GPPGPP Sbjct: 288 ---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344 Query: 390 --PGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNK 447 PG+ G GP G PG G G+RG+ GP G G GPPGPPGI G + GG Sbjct: 345 GSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGING---SPGGKGEMGPA 401 Query: 448 GNDEHE----AGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQ 503 G A G G G G PG G G G+ G GEP +GE+G+ G PGV G++ Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461 Query: 504 GVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGP---PGDVGLPGEHGIPGKQGIKGEK 560 G G+ G PG PG G PG G++G+ G GP GP PG+ G GE G PG G +G Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAA 521 Query: 561 GDPG--GIIGPPGLPGPKGEAGPPGKS-LPGEPGLDGNPGAPGPRGPKGERGLPGVHGSP 617 G+PG G+ G PG+ G G G PG PG PG G G PGP GP G RG PGV G P Sbjct: 522 GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP 581 Query: 618 GDIGPQGI----------------GIPGRTGAQGPAGEPGIQGP------RGLPGLPGTP 655 G G G G PG+ G GP G PG GP G PG G Sbjct: 582 GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ 641 Query: 656 GTPGNDGVPGRDGKPGLPGPPGD---PIALPLLGDIGALLKNFCGNCQASVPGLKSNKGE 712 G PG G PG +GKPG PGP GD P A GD GA + PGL G Sbjct: 642 GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA-------PGERGPPGLAGAPGL 694 Query: 713 EGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGI 772 GGAG PG KG GP GPPG G G +G GERG G PG KGD+G G PG Sbjct: 695 RGGAGPPGPEGG---KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGA 751 Query: 773 PGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIK 832 G PG GP G G G PGP G G+KG G PG PG GP G P ER Sbjct: 752 DGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP-GERGETGP----P 806 Query: 833 GGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP 892 G P PG G PG KG+ G GE G G PG+ G PG G GP GP G+ G G P Sbjct: 807 GPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866 Query: 893 GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGER 952 G PG G PG G GP G G PGP GPSG PG KDG PG G G PG G G + Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPG---KDGPPGPAGNTGAPGSPGVSGPK 923 Query: 953 GDQGIPGDRGSQGERGKPG------LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIP 1006 GD G PG++GS G +G PG + G+ GA G GPPG G GSPG QG G G P Sbjct: 924 GDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKP 983 Query: 1007 GIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPG 1066 G A+ +S E LP A GR G PG DGLPG Sbjct: 984 G--ANGLSGERGPP------------------GPQGLPGLAGTAGEPGRDGNPGSDGLPG 1023 Query: 1067 PPGDPGPQGYRGQKGERGEPGIGLPGSPGLPG-------------------TSALGLPGS 1107 G PG +G RG+ G G P G PG PG PG A G GS Sbjct: 1024 RDGSPGGKGDRGENGSPGAP--GAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGS 1081 Query: 1108 PGAPGPQGPPGPSG 1121 GAPGPQGP G G Sbjct: 1082 RGAPGPQGPRGDKG 1095 Score = 623 bits (1607), Expect = e-178 Identities = 401/911 (44%), Positives = 441/911 (48%), Gaps = 109/911 (11%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G AG PG PG PG GH G PG G G PG PGQ G G G G G G Sbjct: 174 GPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGP------- 226 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRR 411 AG +GE+G G G G PGP G KG G PG P + G G G G G+ G G + Sbjct: 227 --AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK 284 Query: 412 GKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND-EHEAGGLKGDKGETGLPGFP 470 G+ G PG+ G PGP GP G G G +GND + G G G G GFP Sbjct: 285 GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344 Query: 471 GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSA 530 GS G KG+ G G P + G G RGEPG QG G G PGPPG+ GSPG KG+ G A Sbjct: 345 GSPGAKGEVGPAGSPGSNGAPGQRGEPG---PQGHAGAQGPPGPPGINGSPGGKGEMGPA 401 Query: 531 GS------MGPRGPPGDVGLPGEHGI------PGKQGIKGEKGDPG--GIIGPPGLPGPK 576 G MG RGPPG G G G+ PGK G KGE G G G G PG+PG K Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461 Query: 577 GEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQG 635 GE G G PGEPG +G PGA G RG G RG G +G PG+ GP G G PG G +G Sbjct: 462 GEDGKDGS--PGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRG 519 Query: 636 PAGEPGIQGP------RGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGD--PIALPLL-- 685 AGEPG G RG+PG PG PG+ G G PG G+ G PGPPG P P + Sbjct: 520 AAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMG 579 Query: 686 -----GDIGALLKNF--CGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G+ GA KN G G GE G G PG KGD GP GP G Sbjct: 580 FPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQG 639 Query: 739 IPGREGPKGSKGERGYPGIPGEKGDEGLQGIPG---IPGAPGPTGPPGLMGR------TG 789 + G G G GE G PG PG KGD G G PG GAPG GPPGL G G Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAG 699 Query: 790 HPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG------- 842 PGP G KG G GPPG G PG G+P ER G+ S KG P PG Sbjct: 700 PPGPEGGKGAAGPPGPPGAAGTPGLQGMP-GERGGLGSPGP-KGDKGEPGGPGADGVPGK 757 Query: 843 --------PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA 894 P GPPGP G PG GE GA GLPG+ G G G+RG GPPG AG G PG Sbjct: 758 DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQ 817 Query: 895 PGPP------GVPGEPGERGPVGDIGFPGPEGPSGKP---GINGKDGIPGAQGIMGKPGD 945 G P G PGE GE GP G G PG GP+G P G+ G+ G PG G G PG Sbjct: 818 NGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877 Query: 946 R---GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGS 1002 R GP G G+ G PG GS G+ G PG G GA G G G KG G PG +G PG+ Sbjct: 878 RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY-GRPGPPGK 1061 G PG P + I R + P Q G G PG Sbjct: 938 QGPPGAPGPL------------GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985 Query: 1062 DGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSAL----------GLPGSPGA 1110 +GL G G PGPQG G G GEPG G PGS GLPG G PG+PGA Sbjct: 986 NGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGA 1045 Query: 1111 PGPQGPPGPSG 1121 PG GPPGP G Sbjct: 1046 PGHPGPPGPVG 1056 Score = 616 bits (1588), Expect = e-176 Identities = 376/895 (42%), Positives = 430/895 (48%), Gaps = 133/895 (14%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 N G G G PG PG G G PG G G G G G G G +GE G +G G +G Sbjct: 322 NDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQG 381 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 P G+NG G KG++GP G PG G G GPPGP G+ G++G G PGK G +G Sbjct: 382 PPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKG 441 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 G G G+ G PG PG G G + G E A GL G GE G PGF Sbjct: 442 EPGPRGERGEAGIPGVPGAKGEDGKDGSPG-----------EPGANGLPGAAGERGAPGF 490 Query: 470 ---------PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS 520 PG GP G++G PG +G G+ G GV G G++G PG PG PG G Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550 Query: 521 PGLKGQQGSA------GSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPG 574 PG G QG + G GPRG PG +G PG G G G GE+G PGG GP G PG Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGG-PGPQGPPG 609 Query: 575 PKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGV------HGSPGDIGPQG-IGI 627 GE GP G PG G G+ G GP GP+G +GLPG +G PG+ GP+G G Sbjct: 610 KNGETGPQGP--PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGA 667 Query: 628 PGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGD 687 PG G +G AG PG +GP PGL G PG G G PG +G G GPPG P A Sbjct: 668 PGAPGGKGDAGAPGERGP---PGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGA------ 718 Query: 688 IGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKG 747 A PGL+ GE GG G PG KG+ G G G+PG++GP+G Sbjct: 719 -------------AGTPGLQGMPGERGGLGSPG---PKGDKGEPGGPGADGVPGKDGPRG 762 Query: 748 SKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPG 807 G G PG G+ GD+G G PG+PG GP G PG G TG PGP G G G +G PG Sbjct: 763 PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPG 822 Query: 808 KPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGL 867 G G PG G + G GPPGP G KG+ G G PGA G PG Sbjct: 823 GKGERGAPG-----EKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGA 877 Query: 868 EGFPGVKGDRGPAGPPGIAGMSGKPGAPGP---PGVPGEPGERGPVGDI------GFPGP 918 G PG G G GPPG +G GK G PGP G PG PG GP GD G PG Sbjct: 878 RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937 Query: 919 EGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGI------PGDRGSQGERGKPGL 972 +GP G PG G GI GA+G+ G PG GP+G G QG+ PG G GERG PG Sbjct: 938 QGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGP 997 Query: 973 TGMKGAIGPMGPP---GNKGSMGSPGHQGPP---------GSPGIPGIPADAVSFEEIKK 1020 G+ G G G P GN GS G PG G P GSPG PG P + Sbjct: 998 QGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVG- 1056 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PGPQGYR 1077 PA + G GP G G PGP G PGPQG R Sbjct: 1057 -----------------------PAGKSGDR--GESGPAGPAGAPGPAGSRGAPGPQGPR 1091 Query: 1078 GQKGERGEPGI-------GLPGSPGLPGT----SALGLPGSPGAPGPQGPPGPSG 1121 G KGE GE G G PG+PG PG+ G GSPG GP+GP GPSG Sbjct: 1092 GDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146 Score = 612 bits (1579), Expect = e-175 Identities = 396/941 (42%), Positives = 451/941 (47%), Gaps = 172/941 (18%) Query: 289 PN-KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKG--EQGFEGSKGETGEKGEQ 345 PN +G G G PG PG G G+PG G G+PG PG G E G + + + Sbjct: 99 PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSY 158 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPP---------------GPKGEKGDTGPPGPPALP 390 K A+ GL G G G GP GPP GP GE G GP GPP P Sbjct: 159 DVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP 218 Query: 391 GSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450 G++ GP GP GK+G+ GR G+ G G PGPPG GP GI G + G+ D + + Sbjct: 219 GAI---GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF-PGMKGHRGFDGRNGE 274 Query: 451 EHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE 508 + E G GLKG+ G G G PG +GP+G GE G P G G RG G GS G G Sbjct: 275 KGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGP 334 Query: 509 PGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKG------- 561 PG PG G GSPG KG+ G AGS G G PG G PG G G QG G G Sbjct: 335 PGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGG 394 Query: 562 ----DPGGIIGPPGL------PGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGL 610 P GI G PGL PGP G G PG + GEPG +G G PGPRG +GE G+ Sbjct: 395 KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGI 454 Query: 611 PGV---------HGSPGDIGPQGI-------GIPGRTGAQGPAGEPGIQGPRGLPGLP-- 652 PGV GSPG+ G G+ G PG G GP G PG +GP G G P Sbjct: 455 PGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGP 514 Query: 653 ----GTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKS 708 G G PG DGVPG G G+PG PG P G G PG Sbjct: 515 AGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP------GSDGK-------------PGPPG 555 Query: 709 NKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGS------KGERGYPGIPGEKG 762 ++GE G G P G GPRG PG+ G GPKG+ GERG PG PG +G Sbjct: 556 SQGESGRPGPP---------GPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606 Query: 763 DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP---GKPGPPGP----- 814 G G G G PGPTGP G G TG PGP G +G G+ GPP GKPG PGP Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666 Query: 815 -PGIPFNERN----------GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMG 863 PG P + + G++ ++GG GPPGP G KG GP G PGA G Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGA------GPPGPEGGKGAAGPPGPPGAAG 720 Query: 864 LPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSG 923 PGL+G P G+RG G PG G G+PG PG GVPG+ G RGP G IG PGP G G Sbjct: 721 TPGLQGMP---GERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPG 777 Query: 924 KPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIP------GDRGSQGERGKPGLTGMKG 977 G G G+PG G G PG+RG G G G P G+ G +GERG PG G G Sbjct: 778 DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 978 AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVF 1037 G GPPG G G PG QG G G PG P A F Sbjct: 838 PPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPG-----------------------AAGF 874 Query: 1038 LSQLKLPAAMLAAQAYGRPGP---PGKDGLPGP---------PGDPGPQGYRGQKGERGE 1085 LP + G PGP PGKDG PGP PG GP+G GQ GE+G Sbjct: 875 PGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGS 934 Query: 1086 PGI-GLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSG 1121 PG G PG+PG G T A GL G PG PGP+G PGP G Sbjct: 935 PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975 Score = 607 bits (1566), Expect = e-173 Identities = 387/944 (40%), Positives = 439/944 (46%), Gaps = 165/944 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 GE G PG PG+ G +G+ G G +G G PG PG G G G+KGE G G G G P Sbjct: 306 GERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP 365 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGE---KGDTGPPGPPALPGSLGIQGPQGPPGKEGQR 408 G G G G GP GPPG G KG+ GP G P PG +G +GP GP G G Sbjct: 366 GQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAP 425 Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND----EHEAGGLKGDKGET 464 G RG G PGK G G PGP G +G G K G D E A GL G GE Sbjct: 426 GLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485 Query: 465 GLPGF---------PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPP 515 G PGF PG GP G++G PG +G G+ G GV G G++G PG PG P Sbjct: 486 GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP 545 Query: 516 GLIGSPGLKGQQGSAGSMGPRGP------PGDVGLPGEHGIPGKQGIKGEKGDPGGIIGP 569 G G PG G QG +G GP GP PG +G PG G G G GE+G PGG GP Sbjct: 546 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP-GP 604 Query: 570 PGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGV------HGSPGDIGPQ 623 G PG GE GP G PG G G+ G GP GP+G +GLPG +G PG+ GP+ Sbjct: 605 QGPPGKNGETGPQGP--PGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662 Query: 624 G-IGIPGRTGAQGPAGEPGIQGPRGL---PGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679 G G PG G +G AG PG +GP GL PGL G G PG +G G G PG PG G P Sbjct: 663 GDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP 722 Query: 680 IALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE---PGKYDSMARKGDIGPRGP 736 + G+ G L PG K +KGE GG G PGK G IGP GP Sbjct: 723 GLQGMPGERGGL----------GSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772 Query: 737 ------------PGIPGREGPKGSKGERG---------YPGIPGEKGDEGLQGIPGIPGA 775 PG+PG GP+GS GERG +PG PG+ G+ G +G G PG Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGE 832 Query: 776 ------PGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPG------------------KPGP 811 PG GPPG G G PGP G KGE+GS G PG PGP Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP 892 Query: 812 PGPPGIPFNE----------RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA 861 PGP G P + G + KG P G PG GP G PGP+G G Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGI 952 Query: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA---------PGPPGVPG------EPGE 906 G GL G PG+ G RG GP G+ G SGKPGA PGP G+PG EPG Sbjct: 953 TGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGR 1012 Query: 907 RGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGE 966 G G G PG +G G G G++G PGA G G PG GP G G G G+ G G Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072 Query: 967 RGKPGLTGMKGAIGPMGPPGNKGSMGS------PGHQGPPGSPGIPGIPADAVSFEEIKK 1020 G PG G +GA GP GP G+KG G GH+G PG+PG PG P A Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQ------ 1126 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 G G PG G GP G GP G G Sbjct: 1127 --------------------------------QGAIGSPGPAGPRGPVGPSGPPGKDGTS 1154 Query: 1081 GERGEPGIGLPGSPGLPG-TSALGLPGSPGAPGPQGPPGPSGRC 1123 G G IG PG G G + G PG PG PGP GPPG G C Sbjct: 1155 GHPGP--IGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPC 1196 Score = 589 bits (1518), Expect = e-168 Identities = 365/877 (41%), Positives = 422/877 (48%), Gaps = 116/877 (13%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPG-----QKGEQGFEGSK--------- 336 +G G PG PG PG+ G G PG+ G G+PG PG G Q + Sbjct: 105 QGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGV 164 Query: 337 ---GETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSL 393 G G G G G P G +G G G G GPPG G+ G +GPPGPP Sbjct: 165 AVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPP------ 218 Query: 394 GIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 G GP GP GK+G+ GR G+ G G PGPPG GP GI G + G+ D + ++ E Sbjct: 219 GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGF-PGMKGHRGFDGRNGEKGE 277 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPG 513 G G KGE GLPG G+ GP G +G PGE +G G G G G+ G +G G PG Sbjct: 278 TGA-PGLKGENGLPGENGAPGPMGPRGAPGE---RGRPGLPGAAGARGNDGARGSDGQPG 333 Query: 514 PPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGL- 572 PPG G+ G G G+ G +GP G PG G PG+ G PG QG G +G PG PPG+ Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG----PPGIN 389 Query: 573 --PGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGR 630 PG KGE GP G +PG PGL GA GP GP G G PG+ G G G PG+ Sbjct: 390 GSPGGKGEMGPAG--IPGAPGL---MGARGPPGPAGANGAPGLRG--------GAGEPGK 436 Query: 631 TGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGA 690 GA+G G G +G G+PG+PG G G DG PG G GLPG G+ Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGE------------ 484 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 PG + G G GE G G GPRG G PGR+G G G Sbjct: 485 ----------RGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG 534 Query: 751 ERGYPGIPGEKGDEGLQGIPGI------PGAPGPTGP---PGLMGRTGHPGPTGAKGEKG 801 RG PG PG G +G G PG PG PGP+GP PG+MG G G GA G+ G Sbjct: 535 MRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594 Query: 802 SDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA 861 G PG PGP GPPG K G P GPPGP GP GD G G PG Sbjct: 595 ERGGPGGPGPQGPPG---------------KNGETGPQ--GPPGPTGPGGDKGDTGPPGP 637 Query: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGP 921 GL GL G G G+ G G PG G +G PGAPG G G PGERGP G G PG G Sbjct: 638 QGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG 697 Query: 922 SGKPGINGKDGI---PGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGA 978 +G PG G G PG G G PG +G GERG G PG +G +GE G PG G+ G Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 979 IGPMGPPGN---KGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 GP GP G G G PG +G G+PG+PGI S E E Sbjct: 758 DGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGE-----RGETGPPGPAGFP 812 Query: 1036 VFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD------PGPQGYRGQKGERGEPGI- 1088 Q P A G G G G+ GPPG PGPQG +G++G G PG Sbjct: 813 GAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAA 872 Query: 1089 GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G PG+ GLPG G G+PG PGP G PG G P Sbjct: 873 GFPGARGLPGPP--GSNGNPGPPGPSGSPGKDGPPGP 907 Score = 530 bits (1364), Expect = e-150 Identities = 339/818 (41%), Positives = 388/818 (47%), Gaps = 112/818 (13%) Query: 292 GEAGLPGAPGSPGQKGHKGEPG---ENGLHGAPGFPGQKGEQGFEGSKGETGEKG---EQ 345 G GL G G PG+ G KGEPG E G G PG PG KGE G +GS GE G G Sbjct: 423 GAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA 482 Query: 346 GEKGDPALAGLNGENGLKGDLGPHG------PPGPKGEKGDTGPPGPPALPGSLGIQGPQ 399 GE+G P G G NG+ G+ GP G P GP+G G+ G G P PG G+ G Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP 542 Query: 400 GPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG---- 455 G PG +G+ G G G G+PGPPGP GP G G+ G N G + G Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP 602 Query: 456 ---GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP 512 G G GETG G PG GP G KG+ G P G +G +G PG G G G+PG+P Sbjct: 603 GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP---GPQGLQGLPGTGGPPGENGKPGEP 659 Query: 513 GPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHG---IPGKQGIKGEKGDPG--GII 567 GP G G+PG G +G AG+ G RGPPG G PG G PG +G KG G PG G Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719 Query: 568 GPPGL---PGPKGEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDI 620 G PGL PG +G G PG K PG PG DG PG GPRGP G G PG G PGD Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779 Query: 621 GPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPI 680 G G PG G GP G PG +G G PG G PG PG +G PG G+ G PG G+ Sbjct: 780 GEGGA--PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 681 ALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG---------DI 731 + G G G+ A PG + KGE G G PG +G + Sbjct: 838 PPGVAGPPG-------GSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP 890 Query: 732 GPRGPPGIPGREGPKGSKGERGYPGIPG------------EKGDEGLQGIPGIPG----- 774 GP GP G PG++GP G G G PG PG EKG G QG PG PG Sbjct: 891 GPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIA 950 Query: 775 ----APGPTGPPGLMGRTGHPGPTGAKGEKG---SDGPPGKPGPPGPPGIPFNERNGMSS 827 A G GPPG+ G G PGP G KGE G ++G G+ GPPGP G+P G + Sbjct: 951 GITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLP--GLAGTAG 1008 Query: 828 LYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGV---------KGDRG 878 G PG G PG KGD G G PGA G PG G PG +G+ G Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG 1068 Query: 879 PAGPPGIAGMSGKPGAPGP------------------------PGVPGEPGERGPVGDIG 914 PAGP G G +G GAPGP PG PG PG GP G G Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128 Query: 915 FPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTG 974 G GP+G G G G PG G G PG GP G RG++G G GS G G+PG G Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188 Query: 975 MKGAIGP-MGPPGNKGSMGSPGHQGPPGSPGIPGIPAD 1011 GA GP G G G G + +P P D Sbjct: 1189 PPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMD 1226 Score = 476 bits (1224), Expect = e-134 Identities = 300/730 (41%), Positives = 335/730 (45%), Gaps = 115/730 (15%) Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS--------- 520 P GP+G KG+PG P G GD G PG GS PG PGPPG+ S Sbjct: 99 PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS------PGSPGPPGICESCPTGPQNYS 152 Query: 521 --------------PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGD--PG 564 GL G G AG GP GPPG G PG G PG QG GE G P Sbjct: 153 PQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPS 212 Query: 565 GIIGPPGLPGPKGEAGPPGKS----------LPGEPGLDGNPGAPGPRGPKGERGLPGVH 614 G GPPG GP G AG G+S LPG PG+ G G PG G KG RG G + Sbjct: 213 GPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRN 272 Query: 615 GSPGDIGPQGI----GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP 670 G G+ G G+ G+PG GA GP G G G RG PGLPG G GNDG G DG+P Sbjct: 273 GEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQP 332 Query: 671 GLPGPPG------DPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDS 724 G PGPPG P A +G G+ N Q PG + + G +G G PG S Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPG-QRGEPGPQGHAGAQGPPGPPGINGS 391 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 KG++GP G PG PG G +G G G G PG +G G PG GA G GP G Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGE---PGKNGAKGEPGPRGE 448 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPP 844 G G PG GAKGE G DG PG+PG G PG G +G PG Sbjct: 449 RGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAA-----GERGAPGFRGPAGPNGIPGEK 503 Query: 845 GPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGP------P 898 GP G +G PGP G GA G PG +G PG G RG G PG G GKPG PG P Sbjct: 504 GPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRP 563 Query: 899 GVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIP 958 G PG G RG G +GFPGP+G G PG NG+ G PG G G PG G G +G G Sbjct: 564 GPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623 Query: 959 GDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEI 1018 G G +G+ G PG G++G G GPPG G G PG +G G+PG PG DA Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDA------ 677 Query: 1019 KKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG 1078 A G GPPG G PG G GP G G Sbjct: 678 --------------------------------GAPGERGPPGLAGAPGLRGGAGPPGPEG 705 Query: 1079 QKGERGEPG----IGLPGSPGLPGT-SALGLPG------SPGAPGPQGPPGPSGRCNPED 1127 KG G PG G PG G+PG LG PG PG PG G PG G P Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG 765 Query: 1128 CLYPVSHAHQ 1137 + P A Q Sbjct: 766 PIGPPGPAGQ 775 Score = 411 bits (1056), Expect = e-114 Identities = 254/621 (40%), Positives = 286/621 (46%), Gaps = 127/621 (20%) Query: 535 PRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG--KSLPGEP-- 590 P PP G G G PG GI G GDPG PG PG G GPPG +S P P Sbjct: 95 PTRPPNGQGPQGPKGDPGPPGIPGRNGDPG----IPGQPGSPGSPGPPGICESCPTGPQN 150 Query: 591 --------------GLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGP 636 + G G PGP GP G G PG G PG PG G QGP Sbjct: 151 YSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGS--------PGSPGYQGP 202 Query: 637 AGEPGIQGPRGLPGLPGT------PGTPGNDGVPGRDGKPGLPGPPG--DPIALPLLGDI 688 GEPG GP G PG PG G G G PGR G+ GLPGPPG P +P Sbjct: 203 PGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP----- 257 Query: 689 GALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGS 748 PG+K ++G +G GE G+ + KG+ G G G PG GP+G+ Sbjct: 258 -------------GFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGA 304 Query: 749 KGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGK 808 GERG PG+PG G G G G G PGP GPPG G PG GAKGE G G PG Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGT---AGFPGSPGAKGEVGPAGSPGS 361 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLE 868 G PG G P G GPPGPPG G PG GE G G+PG Sbjct: 362 NGAPGQRGEP--------------GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP 407 Query: 869 GFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGIN 928 G G +G GPAG G G+ G G PG G GEPG RG G+ G PG G G+ G + Sbjct: 408 GLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKD 467 Query: 929 GKDGIPGAQGIMGKPGDRGPKGERGD---QGIPGDRGSQGERGKPGLTGMKGAIGPMGPP 985 G G PGA G+ G G+RG G RG GIPG++G GERG PG G +GA G P Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE---P 524 Query: 986 GNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPA 1045 G G G PG +G PGSPG PG Sbjct: 525 GRDGVPGGPGMRGMPGSPGGPG-------------------------------------- 546 Query: 1046 AMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLP 1105 + G+PGPPG G G PG PGP G RGQ G G P G G+ G PG + G Sbjct: 547 ------SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP--GPKGNDGAPGKN--GER 596 Query: 1106 GSPGAPGPQGPPGPSGRCNPE 1126 G PG PGPQGPPG +G P+ Sbjct: 597 GGPGGPGPQGPPGKNGETGPQ 617 Score = 326 bits (835), Expect = 9e-89 Identities = 196/433 (45%), Positives = 225/433 (51%), Gaps = 40/433 (9%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KGE G PG PG G +G GE GE G G GFPG G+ G G KGE G GE+GE G Sbjct: 778 DKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 P +AG G + GP GPPGP+G KG+ G PG P G G +G GPPG G G Sbjct: 838 PPGVAGPPGGS------GPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891 Query: 410 RRGKTGPPGKPGPPGP------PGPPGIQGIHQTLGGYYNKDNKGNDEHEA-------GG 456 G +G PGK GPPGP PG PG+ G G K + G G Sbjct: 892 PPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG 951 Query: 457 LKGDKGETGLPGFP---GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPG 513 + G +G G PG P GS GP+G KGE G+P G G+RG PG G G+ G G+PG Sbjct: 952 ITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011 Query: 514 PPGLIGSPGLKGQQGSAGSMGPR---GPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIG 568 G GS GL G+ GS G G R G PG G PG G PG G G+ GD G G G Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071 Query: 569 PPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IG 626 P G PGP G G PG P G+ G G GA G +G +G G PG GSPG G QG IG Sbjct: 1072 PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131 Query: 627 IPGRTGAQ---GPAGEPGIQGPRGLPGLPGTPGTPGN------DGVPGRDGKPGLPGPPG 677 PG G + GP+G PG G G PG G PG GN +G PG G+PG PGPPG Sbjct: 1132 SPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPG 1191 Query: 678 DPIALPLLGDIGA 690 P P G +GA Sbjct: 1192 AP--GPCCGGVGA 1202 Score = 286 bits (732), Expect = 8e-77 Identities = 182/468 (38%), Positives = 214/468 (45%), Gaps = 83/468 (17%) Query: 733 PRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP---------------- 776 P P P +GP+G KG+ G PGIPG GD G+ G PG PG+P Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNY 151 Query: 777 -------------------------GPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811 GP GPPG G +GHPG G+ G +G G PG+ GP Sbjct: 152 SPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP 211 Query: 812 PGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP 871 GPPG P G S G P PG G PGP G GP G PG G+ G GF Sbjct: 212 SGPPGPP--GAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFD 269 Query: 872 GVKGDRGPAGPPGIAGMSGKP---GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGIN 928 G G++G G PG+ G +G P GAPGP G G PGERG G G G G G G + Sbjct: 270 GRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSD 329 Query: 929 GKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988 G+ G PG G G PG G KGE G G PG G+ G+RG+PG G GA GP GPPG Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGIN 389 Query: 989 GSMGSPGHQGPPGSPGIPGI--------PADAVSFEEIKKYINQEVLRIFE-------ER 1033 GS G G GP G PG PG+ PA A ++ + + ER Sbjct: 390 GSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGER 449 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYR------------GQKG 1081 + +P A G PG PG +GLPG G+ G G+R G G Sbjct: 450 GEAGIP--GVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507 Query: 1082 ERGEPG-------IGLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 ERG PG G PG G+PG + G+PGSPG PG G PGP G Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555 Score = 52.0 bits (123), Expect = 3e-06 Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 16/70 (22%) Query: 1056 PGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQ 1114 P PP P P QG +G KG+ G PGI G G PG+PG PGSPG+PGP Sbjct: 89 PQPP-----TAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQ-----PGSPGSPGPP 138 Query: 1115 G-----PPGP 1119 G P GP Sbjct: 139 GICESCPTGP 148 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 634 bits (1635), Expect = 0.0 Identities = 388/908 (42%), Positives = 443/908 (48%), Gaps = 146/908 (16%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G G PG+KGH+G+PG +G G PG G++G+ G G +G GE Sbjct: 627 KGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGP 686 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGP 383 KG G G P + G++G+ G KG++GP G PGP G++G + GP Sbjct: 687 KGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGP 746 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 G P LPG G GP G PGKEG G +G GPPG GP G PGP G++G G Sbjct: 747 LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 K KG D G+KGD+GE G PG G GP+G KG G G G GE G Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK 866 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGL------KGQQGSAGSMGPRGPPGDVGLPGEHGIPGK 553 +G G+ G PG GP G IG PG KG +G+ G GPRG G G GE G G Sbjct: 867 LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926 Query: 554 QGIKGEKGDPGGI--IGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGE 607 G G KG+ GG GPPG GP G GP G K PG PG DG PG PG RG G Sbjct: 927 TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986 Query: 608 RGLPGVHGSPGDIGPQG----IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGV 663 +G G G PG +GPQG G G G GP G PG QG GL G GT G PG G+ Sbjct: 987 QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046 Query: 664 PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 PG+DG PGL G PGD LP G +GAL GLK N EG G PG Sbjct: 1047 PGKDGPPGLRGFPGDR-GLP--GPVGAL-------------GLKGN---EGPPGPPGPAG 1087 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEG------LQGIPGIPGAPG 777 S +G G GP GIPGR GP+G G G G PGEKG +G LQG G+PG G Sbjct: 1088 SPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG 1147 Query: 778 PTGPPGL---MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNER-------NGMSS 827 P GPPG G G PG G+KG+KG GPPG GP GP G P G Sbjct: 1148 PVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQG 1207 Query: 828 LYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAG 887 L+ KG +PGPPGP G +G PGP GE G G G G PG G RGP+G PG G Sbjct: 1208 LFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG 1267 Query: 888 MSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRG 947 G PG G PG GE GE G G+ G PG GP G G G+ G G G G PG +G Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327 Query: 948 PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPG 1007 P G+ G +G PG G G+ G P G G G GPPG+KG G PG G PG G P Sbjct: 1328 PPGDDGPKGSPGPVGFPGDPGPP---GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP- 1383 Query: 1008 IPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP 1067 G GPPGK G PGP Sbjct: 1384 ----------------------------------------------GPSGPPGKRGPPGP 1397 Query: 1068 PGDPGPQGYRGQKGERGEPG-------IGLPGSPGLPGTSAL-GLPGS------PGAPGP 1113 G G QG +G KGE G G IG G+PG PG L G+PG PG+PGP Sbjct: 1398 AGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGP 1457 Query: 1114 QGPPGPSG 1121 GPPGP G Sbjct: 1458 DGPPGPMG 1465 Score = 609 bits (1570), Expect = e-174 Identities = 379/912 (41%), Positives = 452/912 (49%), Gaps = 116/912 (12%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGE------NGLHGAPG---FPGQKGEQGFEGSKGETGEK 342 G G PG G PG G KGEPG+ G+ G PG PG++G G +G++G G+ Sbjct: 565 GLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQT 624 Query: 343 GEQGEKGDPALAGLNGENGLKGDLGPHGPPGP------KGEKGDTGPPGPPALPGSLGIQ 396 G +G++G LAGL GE G +GD GP GPPGP +G+ G+ GP G P PG G+ Sbjct: 625 GPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLL 684 Query: 397 GPQGPPGK---------EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNK 447 GP+GPPG +GQ G +G GP G+PGPPG G PG QG+ G K Sbjct: 685 GPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEK 744 Query: 448 GNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPF--------------------- 486 G GL G G G PG PG GP G+KG G P Sbjct: 745 G--PLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRG 802 Query: 487 ---TKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVG 543 TKGEKG+ G PG G G+KG+ G+ GPPG G G +G +G G G GP G G Sbjct: 803 LKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPG 862 Query: 544 LPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRG 603 G+ G+PG G G +G P G IG PG PG GE G G+ PG+PG G G GPRG Sbjct: 863 EKGKLGVPGLPGYPGRQG-PKGSIGFPGFPGANGEKG--GRGTPGKPGPRGQRGPTGPRG 919 Query: 604 PKGERGL---PGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPG 659 +G RG+ PG G+ G GP G G G G QGP G PG +GP G PG G PG PG Sbjct: 920 ERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPG 979 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNC-----QASVPGL---KSNKG 711 G G GK G PGPPG G+ G + + + +PGL + KG Sbjct: 980 QRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG 1039 Query: 712 EEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPG---IPGEKGDEGLQG 768 + G AG PGK +G G RG PG G G KG++G G PG PGE+G G G Sbjct: 1040 DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAG 1099 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDG---PPGKPGPPGPPGIPFNERN-- 823 GIPG PGP GPPG G G PG G +G G DG P G PGP GP G P + + Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKG 1159 Query: 824 --GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG 881 G KG PGP GP GP G PGP G G G G +G G KGD GP G Sbjct: 1160 EIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRG 1219 Query: 882 PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941 PG G G G PGPPG GE G+ G +G G PGP GPSG PG +G G PG G G Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279 Query: 942 KPGDRGPKGERGDQGIPGD------RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPG 995 G++G GE G+ G+PG+ +G +GE+G+ G +G G GP GPPG+ G GSPG Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG 1339 Query: 996 HQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGR 1055 G PG PG PG P A Q P G Sbjct: 1340 PVGFPGDPGPPGEPGPA--------------------------GQDGPPGDK------GD 1367 Query: 1056 PGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQ 1114 G PG+ G PGP G+PGP G G++G G G G G G G + GL G PG GP Sbjct: 1368 DGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEA--GLEGPPGKTGPI 1425 Query: 1115 GPPGPSGRCNPE 1126 GP G G+ P+ Sbjct: 1426 GPQGAPGKPGPD 1437 Score = 604 bits (1558), Expect = e-172 Identities = 381/938 (40%), Positives = 438/938 (46%), Gaps = 166/938 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSK-------GETGEKG 343 +G AGLPG PG+ G G G+PGE G G PG PG G G G+ G G+ G Sbjct: 474 EGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAG 533 Query: 344 EQG--------------EKGDPALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGP 386 +G ++ AL G G GL G GP GPPG KGE GD GP GP Sbjct: 534 SKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGP 593 Query: 387 PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDN 446 G+QGP GP GK G+RGR G G G PG GP G G G+ Sbjct: 594 R------GVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGL------------ 635 Query: 447 KGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVK 506 GL G+KG G PG G GP G GE G+ G +G GEPG G G K Sbjct: 636 --------AGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPK 687 Query: 507 GEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGI 566 G PG PGPPG+ G G G +G+ G G GPPG G PG G+PG QG G G+ G + Sbjct: 688 GPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPL 747 Query: 567 IGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGA------PGPRGPKGERGLPGVHGS 616 G PGLPG G GPPG + PGE G G PG PGPRG KG G+ G+ G+ Sbjct: 748 -GKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGT 806 Query: 617 PGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK 669 G+ G G +GI G G GP G G GP G G G G PG G PG GK Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK 866 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG 729 G+PG PG P G IG PG GE+GG G PGK ++G Sbjct: 867 LGVPGLPGYPGRQGPKGSIG-------------FPGFPGANGEKGGRGTPGKPGPRGQRG 913 Query: 730 DIGPRG---PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMG 786 GPRG P GI G+ GPKG+ G G G PGE+G G QG G PG GP GPPG G Sbjct: 914 PTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDG 973 Query: 787 RTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGP 846 GHPG G G +G GPPG PG GP G P E M +PGPPGP Sbjct: 974 LPGHPGQRGETGFQGKTGPPGPPGVVGPQG-PTGETGPMGER----------GHPGPPGP 1022 Query: 847 PGP------------KGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA 894 PG KGDPGP G PG G PGL GFPG +G GP G G+ G G PG Sbjct: 1023 PGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGP 1082 Query: 895 PGPPGVPGEPGERGPVGDIGFPG---------------------PEGPSGKPGINGKDGI 933 PGP G PGE G G G IG PG P+GP+G+ G+ G G+ Sbjct: 1083 PGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142 Query: 934 PGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG------- 986 PG G +G PG+ G KGE G+ G G +G +GE+G PG TG +G IG GP G Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202 Query: 987 --------NKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFL 1038 KG G G GPPG G+ G+P E + Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGD-----------------V 1245 Query: 1039 SQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPG 1098 Q+ P G PG G G PG G+PG G +G+ GE GEPG LPG G PG Sbjct: 1246 GQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG--LPGEGGPPG 1303 Query: 1099 TSA----LGLPGSPGAPGPQGPPGPSGRCNPEDCLYPV 1132 G G GA GP GP GP G P+ PV Sbjct: 1304 PKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV 1341 Score = 598 bits (1542), Expect = e-171 Identities = 380/941 (40%), Positives = 440/941 (46%), Gaps = 158/941 (16%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKG-------ETGEKGE 344 G G G PG PG G G+ G+ G G PG PG G G G G G G+ Sbjct: 472 GPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGD 531 Query: 345 QGEKGDP-----------------ALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPP 384 G KG AL G G GL G GP GPPG KGE GD GP Sbjct: 532 AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ 591 Query: 385 GPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNK 444 GP G+QGP GP GK G+RGR G G G PG GP G G G+ Sbjct: 592 GP------RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGL---------- 635 Query: 445 DNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 GL G+KG G PG G GP G GE G+ G +G GEPG G G Sbjct: 636 ----------AGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLG 685 Query: 505 VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 KG PG PGPPG+ G G G +G+ G G GPPG G PG G+PG QG G G+ G Sbjct: 686 PKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKG 745 Query: 565 GIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGA------PGPRGPKGERGLPGVH 614 +G PGLPG G GPPG + PGE G G PG PGPRG KG G+ G+ Sbjct: 746 P-LGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLK 804 Query: 615 GSPGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD 667 G+ G+ G G +GI G G GP G G GP G G G G PG G PG Sbjct: 805 GTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEK 864 Query: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMAR 727 GK G+PG PG P G IG PG GE+GG G PGK + Sbjct: 865 GKLGVPGLPGYPGRQGPKGSIG-------------FPGFPGANGEKGGRGTPGKPGPRGQ 911 Query: 728 KGDIGP---RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 +G GP RGP GI G+ GPKG+ G G G PGE+G G QG G PG GP GPPG Sbjct: 912 RGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGK 971 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPP 844 G GHPG G G +G GPPG PG GP G P E G + +PGPP Sbjct: 972 DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQG-PTGE----------TGPMGERGHPGPP 1020 Query: 845 GPP------------GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP 892 GPP G KGDPGP G PG G PGL GFPG +G GP G G+ G G P Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPP 1080 Query: 893 GAPGPPGVPGEPGERGPVGDIGFP---------------------GPEGPSGKPGINGKD 931 G PGP G PGE G G G IG P GP+GP+G+ G+ G Sbjct: 1081 GPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV 1140 Query: 932 GIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP------- 984 G+PG G +G PG+ G KGE G+ G G +G +GE+G PG TG +G IG GP Sbjct: 1141 GLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEP 1200 Query: 985 -----------PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 G++G G PG GP G G+PG P + ++ + Sbjct: 1201 GPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPS 1260 Query: 1034 MAVFLSQLKLPAAML----AAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-I 1088 A + P + A G PG G+ GLPG G PGP+G RG+KGE G G Sbjct: 1261 GAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAA 1320 Query: 1089 GLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G PG G PG + G G PG PGP G PGP+G+ P Sbjct: 1321 GPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGP 1361 Score = 577 bits (1486), Expect = e-164 Identities = 367/882 (41%), Positives = 423/882 (47%), Gaps = 160/882 (18%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPG------FPGQKGEQGFEGSKGETGEKGEQ 345 G G+PGA G PG G +G PGE G G PG +PG +G +G +G +G G KGE+ Sbjct: 751 GLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEK 810 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP---------PGP---------- 386 GE G P G G+ G+KGD G GPPGP+GE G GP PGP Sbjct: 811 GEDGFP---GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKL 867 Query: 387 --PALPGSLGIQGPQGP---PGKEGQRGRRGKTGPPGKPGPPG---PPGPPGIQGIHQTL 438 P LPG G QGP+G PG G G +G G PGKPGP G P GP G +G Sbjct: 868 GVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGIT 927 Query: 439 GGYYNKDNKGNDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G K N G D AG G G +G TG PG G GP G+ G PG P +GE G Sbjct: 928 GKPGPKGNSGGDG-PAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986 Query: 494 RGE------PGVIGSQGVKGE---------PGDPGPPGLIGSPGLKGQQGSAGSMGPRG- 537 +G+ PGV+G QG GE PG PGPPG G PGL G++G+ G GP G Sbjct: 987 QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGL 1046 Query: 538 -----PPGDVGLPGEHGIPGKQG---IKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLP 587 PPG G PG+ G+PG G +KG +G PG G G PG GP G AGP G +P Sbjct: 1047 PGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG--IP 1104 Query: 588 GEPGLDGNPG------APGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEP 640 G PG G PG APG +GP+G G G+ G G GP G +G PG G +G GEP Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEP 1164 Query: 641 GIQGPRGLPGLPGTPGTPGNDGV---PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCG 697 G +G +G G G PG G G PG G G PGP G GD G + F G Sbjct: 1165 GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGP--RGFPG 1222 Query: 698 NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGI 757 GL+ G G GE G M G GPRGP G PG +GP+G G G PG Sbjct: 1223 --PPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGA 1280 Query: 758 PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGI 817 GEKG+ G G PG+PG GP GP G G G GP+GA G G GPPG GP G PG Sbjct: 1281 VGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPG- 1339 Query: 818 PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDR 877 V P PGPPG PGP G GP G+ G G PG G PG G+ Sbjct: 1340 ----------------PVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEP 1383 Query: 878 GPAGPPGI---------------------AGMSGKPGAPGPPGVPGEPGERGPVGDIGFP 916 GP+GPPG AG+ G PG GP G G PG+ GP G G P Sbjct: 1384 GPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIP 1443 Query: 917 GPEGPSGKPGINGKDGIPGAQGIMGKPG---DRGPKGERGDQGIPGDRGSQGERGKPGLT 973 GP G G PG G DG PG G G PG D GPKGE+G G+ G G GE+G+ G Sbjct: 1444 GPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDR 1503 Query: 974 GMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 G+ G G GP G +G G G GPPG PG+PG P Sbjct: 1504 GLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKG-------------------- 1543 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQG 1075 A + G GP G+ G PGPPG PGP G Sbjct: 1544 ---------------AKGSSGPTGPKGEAGHPGPPGPPGPPG 1570 Score = 546 bits (1408), Expect = e-155 Identities = 369/921 (40%), Positives = 436/921 (47%), Gaps = 198/921 (21%) Query: 321 PGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGD 380 PG P + + +EG G GEKG+ KG+PA+ E G+ + GPPGP+G G Sbjct: 432 PGMPANQ-DTIYEGIGGPRGEKGQ---KGEPAII----EPGMLIE----GPPGPEGPAGL 479 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQ-GIHQTLG 439 GPPG GP G+ G G RG G PG PG G PGPPG + G Sbjct: 480 PGPPGT------------MGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFG 527 Query: 440 GYYNKDNKGN----DEHEAGG--------LKGDKGETGLPGFPGSVGPKGQ---KGEPGE 484 G + +KG E +A L+G G GL G PG VGP G KGEPG+ Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGD 587 Query: 485 PFTKGEKGDRGEPGV---------IGSQGVKGEPGDPGP------PGLIGSPGLKGQQGS 529 +G +G +G PG GS G +G PG GP GL G PG KG +G Sbjct: 588 VGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGD 647 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G GP GPPGD G G+ G G +G+ GE GP GL GPKG GPPG PG Sbjct: 648 PGPSGPPGPPGDDGERGDDGEVGPRGLPGEP-------GPRGLLGPKGPPGPPGP--PGV 698 Query: 590 PGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLP 649 G+DG PG G GP+GE G PG G+PG G+PG GA GP GE G G GLP Sbjct: 699 TGMDGQPGPKGNVGPQGEPGPPGQQGNPG-----AQGLPGPQGAIGPPGEKGPLGKPGLP 753 Query: 650 GLPGT---PGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGL 706 G+PG PG PG +G PG G G PGP G PI P G G +K G + GL Sbjct: 754 GMPGADGPPGHPGKEGPPGEKGGQGPPGPQG-PIGYP--GPRG--VKGADG-----IRGL 803 Query: 707 KSNKGEEGGAGEPGKYDSMARKGD---IGPRGP--------------------------- 736 K KGE+G G PG M KGD IGP GP Sbjct: 804 KGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGE 863 Query: 737 ---------PGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP------ 781 PG PGR+GPKGS G G+PG GEKG G G PG G GPTGP Sbjct: 864 KGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGP 923 Query: 782 ------PGLMGRTGHPGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNE----RNGMSSL 828 PG G +G GP G GE+G +GP G PGP GPPG P + G Sbjct: 924 RGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGE 983 Query: 829 YKIKGGVNVPSYPGPPGPPGPKGDPGPVGE---PGAMGLPGLEGFPGVKGDRGPAGPPGI 885 +G P PG GP GP G+ GP+GE PG G PG +G PG+ G G G PG Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043 Query: 886 AGMSGKPGAPGPPGVPGEPGERGPVGDIGF------PGPEGPSGKPGINGKDGIPGAQGI 939 AG+ GK G PG G PG+ G GPVG +G PGP GP+G PG G G G GI Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGI 1103 Query: 940 MGKPGDRGPKGERGDQGIPGDRGSQGERGKPGL---TGMKGAIGPMGPP---GNKGSMGS 993 G+PG +GP G G++G PG++G QG G+ GL G+ G GP+GPP G+KG +G Sbjct: 1104 PGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGE 1163 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 PG +G G G G P I Sbjct: 1164 PGQKGSKGDKGEQGPPGPTGPQGPI----------------------------------- 1188 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG----IGLPGSPGLPG----TSALGLP 1105 G+PGP G DG PGP G G G +G +G RG PG +GL G PG PG T +G Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM 1248 Query: 1106 GSPGAPGPQGPPGPSGRCNPE 1126 G PG PGP+GP G G P+ Sbjct: 1249 GPPGPPGPRGPSGAPGADGPQ 1269 Score = 536 bits (1382), Expect = e-152 Identities = 326/758 (43%), Positives = 389/758 (51%), Gaps = 100/758 (13%) Query: 291 KGEAGLPGAPGSPGQKGHKGE---------PGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 KG+ G+PG PG PG++G KG GE G G PG PG +G++G G +GE G Sbjct: 864 KGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGP 923 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPA---LPGSLGIQG- 397 +G G+ G +G +G G G+ GP+GP GP G G GPPGPP LPG G +G Sbjct: 924 RGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGE 983 Query: 398 --------PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGN 449 P GPPG G +G G+TGP G+ G PGPPGPPG QG L G K+ Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQG----LPGLAGKEGTKG 1039 Query: 450 DEHEAG--------GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIG 501 D AG GL+G G+ GLPG G++G KG +G PG P G G+RG G G Sbjct: 1040 DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAG 1099 Query: 502 SQGVKGEPGDPGPPGLIG---SPGLKGQQGSAGS------------MGPRGPPGDVGLPG 546 G+ G PG GPPG G +PG KG QG AG GP GPPG+ G G Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKG 1159 Query: 547 EHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPG 597 E G PG++G KG+KG+ G G GP G PGP G G PG + L G+ G +G G Sbjct: 1160 EIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRG 1219 Query: 598 APGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG 656 PGP GP G +GLPG G G+ G G +G PG G +GP+G PG GP+G PG G PG Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279 Query: 657 TPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA 716 G G PG G+PGLPG G P G+ G + A PG K G++G Sbjct: 1280 AVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGA----AGPPGPKGPPGDDGPK 1335 Query: 717 GEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP 776 G PG + GD GP G PG G++GP G KG+ G PG + G G G PG G P Sbjct: 1336 GSPGP---VGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG---QTGSPGPTGEPGPSGPP 1389 Query: 777 GPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVN 836 G GPPG G G G GAKGE G +GPPGK GP GP G P Sbjct: 1390 GKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAP------------------ 1431 Query: 837 VPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPG 896 G PGP G +G PGPVGE G G PG +G PG G G G G +G G+ G PG Sbjct: 1432 -----GKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPG 1486 Query: 897 PPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQG 956 G+ G PGE+G GD G PGP+G SG G QGI G G GP G G G Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGP---------KGEQGITGPSGPIGPPGPPGLPG 1537 Query: 957 IPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSP 994 PG +G++G G G G G GP GPPG G + P Sbjct: 1538 PPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQP 1575 Score = 421 bits (1081), Expect = e-117 Identities = 295/795 (37%), Positives = 360/795 (45%), Gaps = 152/795 (19%) Query: 414 TGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG----- 468 T P PP G ++G T N D D + + G+P Sbjct: 383 TSNSSNPAPPPGEGADDLEG-EFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTI 441 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 + G GP+G+KG+ GEP EPG++ ++G PG GP GL G P Sbjct: 442 YEGIGGPRGEKGQKGEPAII-------EPGML----IEGPPGPEGPAGLPGPP------- 483 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSL-- 586 G GP G VG PGE G PG+ PGLPG G GPPG L Sbjct: 484 -----GTMGPTGQVGDPGERGPPGR----------------PGLPGADGLPGPPGTMLML 522 Query: 587 PGEPGLDGNPGAPGP--------------------RGPKGERGLPGVHGSPGDIGPQGIG 626 P G G+ G+ GP RGP G GL G PG +GP Sbjct: 523 PFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTG---RPGPVGP---- 575 Query: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLG 686 PG G +G G+ G QGPRG+ G PG G PG G G DG G+PG G G Sbjct: 576 -PGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPK------G 628 Query: 687 DIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 D G F G A +PG K ++G+ G +G PG +GD G GP G+PG GP+ Sbjct: 629 DRG-----FDG--LAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPR 681 Query: 747 GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP 806 G G +G PG PG G G+ G PG G GP G PG G+ G+PG G G +G+ GPP Sbjct: 682 GLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPP 741 Query: 807 GKPGPPGPPGIP-FNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLP 865 G+ GP G PG+P +G +G GPPGP GP G PGP G GA G+ Sbjct: 742 GEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR 801 Query: 866 GL---------EGFPG------VKGDRGPAGPPGIAGMSGKPGA---------PGPPGVP 901 GL +GFPG +KGDRG GPPG G G G PGP G P Sbjct: 802 GLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPP 861 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 GE G+ G G G+PG +GP G G G G G +G G PG GP+G+RG G G+R Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGER 921 Query: 962 GSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS------PGHQGPPGSPGIPGIPADAVSF 1015 G +G GKPG G G GP GPPG +G G PG +GPPG PG G+P Sbjct: 922 GPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPG----- 976 Query: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQA-YGRPGPPGKDGLPGPPGDPGPQ 1074 + Q F+ + P ++ Q G GP G+ G PGPPG PG Q Sbjct: 977 -----HPGQRGETGFQGKTGP-----PGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026 Query: 1075 GY---RGQKGERGEPGI-------------GLPGSPGLPG-TSALGLPGSPGAPGPQGPP 1117 G G++G +G+PG G PG GLPG ALGL G+ G PGP GP Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086 Query: 1118 GPSGRCNPEDCLYPV 1132 G G P P+ Sbjct: 1087 GSPGERGPAGAAGPI 1101 Score = 326 bits (836), Expect = 7e-89 Identities = 182/404 (45%), Positives = 212/404 (52%), Gaps = 29/404 (7%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347 I G +G G PG GQ+G G+ G+ G G PG PG G QG G GE GE G+ G+ Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247 Query: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 G P G G +G G GP GPPG G G G G P G G+ G GPPG +G+ Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE 1307 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 RG +G++GP G GPPGP GPPG G + G G GD G G P Sbjct: 1308 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV--------------GFPGDPGPPGEP 1353 Query: 468 GFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQ- 526 G G GP G KG+ GEP G G GEPG G G +G PG GP G G G KG+ Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEA 1413 Query: 527 -----QGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPK 576 G G +GP+G PG G G GIPG G +G G PG G +GPPGLPG K Sbjct: 1414 GLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLK 1473 Query: 577 GEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGP 636 G++GP G+ G PGL G G PG +G KG+RGLPG GS G G Q GI G +G GP Sbjct: 1474 GDSGPKGEK--GHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ--GITGPSGPIGP 1529 Query: 637 AGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPI 680 G PG+ GP G G G+ G G G G G PG PGPPG+ I Sbjct: 1530 PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVI 1573 Score = 125 bits (315), Expect = 2e-28 Identities = 77/168 (45%), Positives = 85/168 (50%), Gaps = 30/168 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG---------- 340 KGEAGL G PG G G +G PG+ G G G PG GEQG GS G G Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGL 1469 Query: 341 -----EKGEQGEKGDPALAGL---NGENGLKGDLG---PHGPPGPKGEKGDTGP------ 383 + G +GEKG P L GL GE G KGD G P G GPKGE+G TGP Sbjct: 1470 PGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGP 1529 Query: 384 PGPPALPGS---LGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGP 428 PGPP LPG G +G GP G +G+ G G GPPG PG P P Sbjct: 1530 PGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLP 1577 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 625 bits (1613), Expect = e-179 Identities = 414/994 (41%), Positives = 469/994 (47%), Gaps = 206/994 (20%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347 + KGE G PG G PG+ G KGE G G G PG+PG G QG +G KGE G G G Sbjct: 274 VGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGI 333 Query: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL-----------PGSLGIQ 396 G GE G G GP G PGPKG G G PGPP L PG G + Sbjct: 334 VIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEK 393 Query: 397 GPQGPPGKE--GQRGRRGKTGPPGKPGPPGPP-----------------GPPGIQGIHQT 437 G +G PG G GR G GPPG PGPPG P GPPGI G Sbjct: 394 GDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGF 453 Query: 438 LGGYYNKDNKGN-----DEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 +G K KG D G G +G G GFPG G KG +G PG G G Sbjct: 454 IGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPG 513 Query: 493 DRGEPGVIGSQGVKGEPGD----------------PGPPGLIGSPGLKGQQGSAGSMGPR 536 +G PG+IG G KGEPG+ PG PG+ G G G+ G G GP+ Sbjct: 514 PQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPK 573 Query: 537 GPPGDVGLPGEHGIPGKQGIKGEKGDPG----------------------GIIGPPGLPG 574 G PG VGL GE G PG G G +GD G G G PGLPG Sbjct: 574 GSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPG 633 Query: 575 PKGEAGPPGK--SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSP------GDIGPQGIG 626 PKGE PGK LPG PG +G PG+PG GP+G+RG PG G P G +G GIG Sbjct: 634 PKGE---PGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 690 Query: 627 IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGV-----------PGRDGKPGLPGP 675 PG G +G G PG GP G PG PG G PGN GV PG G PGLPG Sbjct: 691 FPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGI 750 Query: 676 PGDP-----IALP-LLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG 729 PG P I +P + G+ GA+ PGL+ +GE G G PG S G Sbjct: 751 PGTPGEKGSIGVPGVPGEHGAI----------GPPGLQGIRGEPGPPGLPGSVGSPGVPG 800 Query: 730 DIGP---RGPP---GIPGREGPKGSKGERGYPG-----IPGEKGDEGLQGIPGIPGAPGP 778 IGP RGPP G PG GP G KGE+G+PG +PG KGD+G QG+PGI G G Sbjct: 801 -IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGL 859 Query: 779 TGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGP---PGIPFNERN----------GM 825 G PG G G PG G+KGE G G PG+PG PGP PG+P + + G Sbjct: 860 PGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGD 919 Query: 826 SSLYKIKGGVNVPSYP------------GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGV 873 L KG V +P P G G G KG GP+GE G+ G PG PGV Sbjct: 920 PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGT---PGV 976 Query: 874 KGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGI 933 G G AG PG G G PG G PG PG PG +G VG +G PG G G P GI Sbjct: 977 PGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP------GI 1030 Query: 934 PGAQGIMGKPGDRGPKGERGDQ-----GIPGDRGSQGER------GKPGLTGMKGAIGPM 982 PG QG G PGD+G KGE+G GIPG RG +G++ G PG G KG+IG Sbjct: 1031 PGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090 Query: 983 GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK 1042 G PG+ G GSPG G PGSPG+PG D L L Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDK------------------------GLPGLD 1126 Query: 1043 -LPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSA 1101 +P A G PGP G G G PG G G G+KGE G PG G PG PG G Sbjct: 1127 GIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG 1186 Query: 1102 L-------GLPGSPGAPGPQ------GPPGPSGR 1122 GL GSPG PG + GPPGP G+ Sbjct: 1187 SKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQ 1220 Score = 615 bits (1586), Expect = e-176 Identities = 387/893 (43%), Positives = 456/893 (51%), Gaps = 142/893 (15%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGE----------NGLHGAPGFPGQKGEQGFEGSKG 337 I +KG+AG PG PGSPG G KGEPG+ GL G+PGFPG +G++GF G+ G Sbjct: 614 IGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPG 673 Query: 338 ETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPA------LPG 391 G GE+G G P + G GP GP G G GD GPPG P LPG Sbjct: 674 RPGLPGEKGAVGQPGI----------GFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG 723 Query: 392 SLGIQGPQGPPGK--EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGN 449 + G+QG +G PG G +G G G PG PG G G PG+ G H +G Sbjct: 724 NPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIG---------- 773 Query: 450 DEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEP 509 GL+G +GE G PG PGSVG G G G P +G G +G PG+ G G+KGE Sbjct: 774 ----PPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGGQGPPGLSGPPGIKGEK 828 Query: 510 GDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGP 569 G PG PGL PG KG +G+ G G G G GLPG+ G PG G G KG+ G ++G Sbjct: 829 GFPGFPGL-DMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMG-VMGT 886 Query: 570 PGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP------KGERGLPGVHGS------- 616 PG PG G G PG LPGE G G PG+ GPRG KG+ GLPG GS Sbjct: 887 PGQPGSPGPVGAPG--LPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMG 944 Query: 617 -----------PGDIGPQGI-------GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTP 658 G IGP G G PG G G AG+PG GP+G PG+ GTPG P Sbjct: 945 SMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP 1004 Query: 659 GNDG------------VPGRDGKPGLPGPPGDPIALPLLGDIGAL-LKNFCGNCQASVPG 705 G G PG G PG+PGP G P LP GD GA K G +PG Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSP-GLP--GDKGAKGEKGQAGPPGIGIPG 1061 Query: 706 LKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEG 765 L+ KG++G AG PG KG IG G PG PG +G GS G G PG+PGEKGD+G Sbjct: 1062 LRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKG 1121 Query: 766 LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP---FNER 822 L G+ GIPG G G PG G TG P G KGE GSDG PG G G PG+P F Sbjct: 1122 LPGLDGIPGVKGEAGLPGTPGPTG---PAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGF 1178 Query: 823 NGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPG-----VKGDR 877 G KG V P G PG PG KG+ G +G PG G PGL G PG KGDR Sbjct: 1179 PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDR 1238 Query: 878 GPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQ 937 GP G PG+ G+ G G PG PG+ G G++G G G PG GP G PG G GI G+ Sbjct: 1239 GPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP 1298 Query: 938 GIMGKPGDRGPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN----KGS 990 GI G GD GP G +G +G+PG +G +G++G G+ G KG GP GPPG KG Sbjct: 1299 GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGE 1358 Query: 991 MGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAA 1050 G PG +GPPG G+ G+P Q V + + +P Sbjct: 1359 PGLPGPEGPPGLKGLQGLPGPKGQ---------QGVTGL-----------VGIP------ 1392 Query: 1051 QAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSAL 1102 G PG PG DG PG G+ GP G G +G G PG GLPGS G PGT ++ Sbjct: 1393 ---GPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442 Score = 607 bits (1566), Expect = e-173 Identities = 395/953 (41%), Positives = 463/953 (48%), Gaps = 140/953 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE-------KG 343 +G G G PG PG KG +G PG +G+ G PG G G G G+KGE GE KG Sbjct: 482 QGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKG 541 Query: 344 EQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGE------KGDTGPPGPPALPGSLGIQG 397 ++G+ G P G+ G G G G G PGPKG KG+ GPPG PGS G G Sbjct: 542 DKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTG 601 Query: 398 PQGPPG--KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG 455 P GPPG G G +G+ G PG PG PG PGP G G L G Sbjct: 602 PPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGP-------------- 647 Query: 456 GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV-----IGSQGVKGEPG 510 G +G G PGFPG G +G G PG P GEKG G+PG+ G +GV G PG Sbjct: 648 --PGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPG 705 Query: 511 DPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG------ 564 D GPPG G PG G G+ G G +G PG VGLPG G+PG GI G G+ G Sbjct: 706 DMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764 Query: 565 -----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA--PGPRGPKGERGLPGVHGSP 617 G IGPPGL G +GE GPPG LPG G G PG PG RGP G +G PG+ G P Sbjct: 765 VPGEHGAIGPPGLQGIRGEPGPPG--LPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPP 822 Query: 618 GDIGPQG------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK-- 669 G G +G + +PG G +G G PGI G GLPGLPG G PG G PG G+ Sbjct: 823 GIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMG 882 Query: 670 ----PGLPGPPGDPIALPLLGDIGALLKNFCGNC-QASVPGLKSNKGEEGGAGEPGKYDS 724 PG PG PG A L G+ G F G+ PGLK +KG+ G G+PG D Sbjct: 883 VMGTPGQPGSPGPVGAPGLPGEKGD--HGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDK 940 Query: 725 M------------ARKGDIGP---RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769 + KG IGP +G G PG G G G+ G PG PG KGD G+ G Sbjct: 941 VDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGT 1000 Query: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPG---------PPGIPFN 820 PG PG PGP G G MG G PG G G G G PG PG G PPGI Sbjct: 1001 PGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIP 1060 Query: 821 ERNGMSSLYKIKGGVNVPS---------YPGPPGPPGPKGDPGPVGEPGA---------M 862 G I G P PG PG PG KG PG VG PG+ Sbjct: 1061 GLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDK 1120 Query: 863 GLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVG-----DIGFPG 917 GLPGL+G PGVKG+ G G PG G +G+ G PG G+PG GE+G G GFPG Sbjct: 1121 GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPG 1180 Query: 918 PEGPSGK------PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD-----RGSQGE 966 +G G PG+ G GIPG++G G G GP+G+ G G PG +G +G Sbjct: 1181 AKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGP 1240 Query: 967 RGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEV 1026 +G+PGL G+ G +GP G PG G G G+ G PG+PG+PG D F+ + Sbjct: 1241 QGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDP-GFQGMPGIGGSPG 1299 Query: 1027 LRIFEERMAV-----FLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGP----QGYR 1077 + + M F LP G G PG GLPGPPG PGP +G Sbjct: 1300 ITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP 1359 Query: 1078 GQKGERGEPGI----GLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSGRCNP 1125 G G G PG+ GLPG G G + L G+PG PG PG G PG G P Sbjct: 1360 GLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGP 1412 Score = 601 bits (1549), Expect = e-171 Identities = 397/948 (41%), Positives = 466/948 (49%), Gaps = 169/948 (17%) Query: 290 NKGEAGLPGAPGSPGQ-----------KGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 +KG+ G+ G PG PGQ KG KG+ GE G G PG G+KGE G G +G+ Sbjct: 230 DKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGV-GEKGEPGKPGPRGK 288 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGP 398 G+ G++GEKG P G GE G G +G GP G KGE G GPPG G LG +G Sbjct: 289 PGKDGDKGEKGSP---GFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGE 345 Query: 399 QGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLK 458 +G PG G RG G G PG PG PGPPG P + G G + KG+ L Sbjct: 346 RGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP-VPGQAGAPGFPGERGEKGDRGFPGTSLP 404 Query: 459 GDKGETGLPGFPGSVGPKGQKG--------EPGEPFTKGEKGDRGEPGVIGSQGVKGE-- 508 G G GLPG PGS GP GQ G +PG P +G G G+PG IG G KG+ Sbjct: 405 GPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKG 464 Query: 509 --------------PGDPGPPGLIGSPG---------LKGQQGSAGSMGPRGPPGDVGLP 545 PG GPPG IG PG L G+ G AG GP+G PG +G P Sbjct: 465 ESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQP 524 Query: 546 GEHGIPGK----QGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP 601 G G PG+ +KG+KGDPG PG PG G AG PG+ G PGL G G+PG Sbjct: 525 GAKGEPGEFYFDLRLKGDKGDPGF----PGQPGMTGRAGSPGRD--GHPGLPGPKGSPGS 578 Query: 602 RGPKGERGLPGVHGSPG---DIGPQG---------IGIPGRTGAQGPAGEPGIQGPRG-- 647 G KGERG PG G PG D GP G IG G+ G G G PG+ GP+G Sbjct: 579 VGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEP 638 Query: 648 -----LPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702 LPG PG G PG+ G PG G G PG PG P LP G+ GA+ G Sbjct: 639 GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP-GLP--GEKGAV-----GQPGIG 690 Query: 703 VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGS-----KGERGYPGI 757 PG KG +G G+ G + R G G G PG+ G++G G KG G PGI Sbjct: 691 FPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGI 750 Query: 758 PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDG-----PPGKPGPP 812 PG G++G G+PG+PG G GPPGL G G PGP G G GS G PPG GPP Sbjct: 751 PGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPP 810 Query: 813 GPPGIPFNERNGMSSLYKIKGGVNVPSYPG--PPGPPGPKGD---PGPVGEPGAMGLPGL 867 G G P G+S IKG P +PG PGP G KG PG G+ G GLPG Sbjct: 811 GGQGPP-----GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQ 865 Query: 868 EGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI 927 +G PG+ G G G G+ G G+PG+PGP G PG PGE+G D GFPG GP G PG+ Sbjct: 866 QGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG---DHGFPGSSGPRGDPGL 922 Query: 928 NGKDG---IPGAQGIM---------GKPGDRGPKGE---------RGDQGIPGDRGSQGE 966 G G +PG G M G+ GD+G KG+ RGD G PG G G+ Sbjct: 923 KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982 Query: 967 RGKPGLTGMK------GAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 G+PG G K G G G PG KGS+G G G PG G+PGIP S Sbjct: 983 AGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGS------ 1036 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPP--GKDGLPGPPGDPGPQGYRG 1078 LP A G+ GPP G GL G GD G G+ G Sbjct: 1037 --------------------PGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPG 1076 Query: 1079 QKGERGEPG-IGLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSG 1121 GE+GE G IG+PG PG PG ++G PGSPG PG +G G G Sbjct: 1077 SPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPG 1124 Score = 595 bits (1534), Expect = e-170 Identities = 381/930 (40%), Positives = 451/930 (48%), Gaps = 144/930 (15%) Query: 284 QCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKG 343 +C C KG+ G G PG G G G G G G PG G GE G G+KG G G Sbjct: 38 KCDCHGVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPG 97 Query: 344 EQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G+P L G+ G++G G P G PG G KG+ GP GPP LPG G GP G PG Sbjct: 98 ASGYPGNPGLPGIPGQDGPPG---PPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPG 154 Query: 404 KEGQRGR----------RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 +G G +G+ G PG PG PGPPG PG+Q Sbjct: 155 MKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQ--------------------- 193 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV-------- 505 G G G TG PG PG GP G+KG+ G F +G KGD+G+ GV G GV Sbjct: 194 --GPVGPPGFTGPPGPPGPPGPPGEKGQMGLSF-QGPKGDKGDQGVSGPPGVPGQAQVQE 250 Query: 506 ------KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE 559 KGE G G PG G PG+ G++G G GPRG PG G GE G P G GE Sbjct: 251 KGDFATKGEKGQKGEPGFQGMPGV-GEKGEPGKPGPRGKPGKDGDKGEKGSP---GFPGE 306 Query: 560 KGDPGGIIGPPGLPGPKGEAGPP-------GKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 G P G+IG G G KGEAGPP G GE G G PG PGPRG G +G PG Sbjct: 307 PGYP-GLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPG 365 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLP-----------GLPGTPGTPGND 661 + G P GP G+ +PG+ GA G GE G +G RG P GLPG PG+PG Sbjct: 366 LPGQP---GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPP 422 Query: 662 GVPG--------RDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEE 713 G PG + G PG GPPG P +G+IG + + G + G + Sbjct: 423 GQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQ 482 Query: 714 GGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD-------EGL 766 G GE G KGD G G G+ G GP+G+ G G PG GE G+ +G Sbjct: 483 GPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD 542 Query: 767 QGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN--- 823 +G PG PG PG TG G GR GHPG G KG GS G G+ GPPG G P + + Sbjct: 543 KGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGP 602 Query: 824 ------GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV----GEPGAMGLPGLEGFPGV 873 G + KG P PG PG PGPKG+PG + G PGA GLPG GFPG Sbjct: 603 PGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGP 662 Query: 874 KGDRGPAGPPGIAGMSGK-----------PGAPGPPGVPGEPGERGPVGDIGFPGPEGPS 922 +GDRG G PG G+ G+ PG PGP GV G PG+ GP G G PG G Sbjct: 663 QGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLP 722 Query: 923 GKPGINGKD-----GIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKG 977 G PG+ G+ G+PG +G+ G PG G GE+G G+PG G G G PGL G++G Sbjct: 723 GNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRG 782 Query: 978 AIGPMGPPGNKGS-----MGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEE 1032 GP G PG+ GS +G PG +GPPG G PG+ I E Sbjct: 783 EPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPP---------------GIKGE 827 Query: 1033 RMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLP 1091 + L +P A G PG G+ GLPG PG G G G G +GE G+ G P Sbjct: 828 KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTP 887 Query: 1092 GSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G PG PG +G PG PG G G PG SG Sbjct: 888 GQPGSPG--PVGAPGLPGEKGDHGFPGSSG 915 Score = 583 bits (1504), Expect = e-166 Identities = 395/997 (39%), Positives = 457/997 (45%), Gaps = 213/997 (21%) Query: 291 KGEAGLPGA------PGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGE 344 KGE GLPG PG G +G +G PG+ G G PG PG KG +G G+ G G G Sbjct: 48 KGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL 107 Query: 345 QG---EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL-----------P 390 G + G P G+ G NG KG+ GP GPPG G G+ GPPG P + P Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP 167 Query: 391 GSL-----GIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKD 445 G L G G G PG G G +G GPPG GPPGPPGPPG G K Sbjct: 168 GMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG---------EKG 218 Query: 446 NKGNDEHEAGGLKGDKGETGLPGFPGSV-----------GPKGQKGEPG--------EPF 486 G G KGD+G +G PG PG G KGQKGEPG E Sbjct: 219 QMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKG 278 Query: 487 TKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPP------G 540 G+ G RG+PG G +G KG PG PG PG G G +G QG G GP GPP G Sbjct: 279 EPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTG 338 Query: 541 DVGLPGEHGIPGKQGIKGE---KGDPG--GIIGPPGLP--------------GPKGEAGP 581 +G GE G PG G +GE KG PG G GPPGLP G KG+ G Sbjct: 339 PLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGF 398 Query: 582 PGKSLPGEPGLDGNPGAPGPRGPKGERGLPG-----VHGSPGDIGPQGI----GIPGRTG 632 PG SLPG G DG PG PG GP G+ G G PGD GP GI G G G Sbjct: 399 PGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIG 458 Query: 633 AQGPAGE-------------PGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679 +G GE PG QGP G G PG PG G+ G+PGRDG G+PGP G P Sbjct: 459 EKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTP 518 Query: 680 IALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGI 739 L+G GA K G + LK +KG+ G G+PG R G G G PG+ Sbjct: 519 ---GLIGQPGA--KGEPGEFYFDLR-LKGDKGDPGFPGQPGM---TGRAGSPGRDGHPGL 569 Query: 740 PGREGPKGS---KGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA 796 PG +G GS KGERG PG G G G G PG PG GP GP G G+ G PG G+ Sbjct: 570 PGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGPGS 628 Query: 797 KGEKGSDGPPGK----PGPPGPPGIP-------------FNERNGMSSLYKIKGGVNVPS 839 G G G PGK PGPPG G+P F G L KG V P Sbjct: 629 PGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPG 688 Query: 840 --YPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGP 897 +PGPPGP G G PG +G PG G PG G PG G +G G PG+ G+ G G PG Sbjct: 689 IGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV-GLPGLKGLPGL 747 Query: 898 PGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI-----------MGKPGDR 946 PG+PG PGE+G +G G PG G G PG+ G G PG G+ +G PG R Sbjct: 748 PGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGAR 807 Query: 947 GPKGERGDQGIPGDRGSQGERGKPGLTGM-----KGAIGPMGPPGNKGSMGSPGHQGPPG 1001 GP G +G G+ G G +GE+G PG G+ KG G G PG G G PG G G Sbjct: 808 GPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQG 867 Query: 1002 SPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGK 1061 +PGIPG P M G+PG PG Sbjct: 868 APGIPGFPGSK--------------------------------GEMGVMGTPGQPGSPGP 895 Query: 1062 DGLPGPPGDPGPQGYRGQKGERGEPG-------IGLPGSPG------------------- 1095 G PG PG+ G G+ G G RG+PG +GLPG PG Sbjct: 896 VGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGE 955 Query: 1096 ------LPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 + + G PG+PG PG G G G+ P+ Sbjct: 956 KGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPK 992 Score = 516 bits (1328), Expect = e-146 Identities = 325/754 (43%), Positives = 387/754 (51%), Gaps = 107/754 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGA---PGFPGQKGEQGFEGSKGETGEKG---- 343 KG GLPG PG+PG+KG G PG G HGA PG G +GE G G G G G Sbjct: 742 KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI 801 Query: 344 ----EQGEKGDPALAGLNGENGLKGDLGPHG-----PPGPKGEKGDTGPPGP------PA 388 +G G GL+G G+KG+ G G PGPKG+KG G PG P Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPG 861 Query: 389 LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKG 448 LPG G G G PG +G+ G G G PG PGP G PG PG +G H G+ Sbjct: 862 LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDH----GFPGSSGPR 917 Query: 449 NDEHEAGGLKGDKGETGLPGFPGSV---------GPKGQKGEPGEPFTKGEKGDRGEPGV 499 D GLKGDKG+ GLPG PGS+ G KG +GE G+ GEKG RG+PG Sbjct: 918 GDP----GLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGT 973 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE 559 G G G+ G PG PG G PG+ G G+ G GP+G G +GLPG G G GI G Sbjct: 974 PGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGP 1033 Query: 560 KGDPGGIIGPPGLPGPKGEAGPPGKSLPG------EPGLDGNPGAPGPRGPKGERGLPGV 613 +G PG + G G G KG+AGPPG +PG + G+ G PG+PG +G KG G+PG+ Sbjct: 1034 QGSPG-LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGM 1092 Query: 614 HGSPGDIG-PQGIGIPGRTGAQGPAGEPGIQGPRGLPG------LPGTPGT--------- 657 GSPG G P +G PG G G G+ G+ G G+PG LPGTPG Sbjct: 1093 PGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGE 1152 Query: 658 PGNDGVPG---RDGKPGLPGP--PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGE 712 PG+DG+PG G+PGLPG PG P A G G + F G A PG+ +KGE Sbjct: 1153 PGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEV--GFPG--LAGSPGIPGSKGE 1208 Query: 713 EGGAGEPGK-----------YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEK 761 +G G PG + + KGD GP+G PG+PG GP G G PGI G K Sbjct: 1209 QGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPG---LPGIDGVK 1265 Query: 762 GDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE 821 GD+G G PG PG PGP G PG G G G G G KG GPPG PG GP G+P Sbjct: 1266 GDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLP--- 1322 Query: 822 RNGMSSLYKIKGGVNVPS---YPGPPGPPGP----KGDPGPVGEPGAMGLPGLEGFPGVK 874 G+ + +G VP PGPPGPPGP KG+PG G G GL GL+G PG K Sbjct: 1323 --GLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPK 1380 Query: 875 GDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934 G +G G + G+ G PG PG G PG+ GE GP GP GP G PG G DG+P Sbjct: 1381 GQQGVTG---LVGIPGPPGIPGFDGAPGQKGEMGPA------GPTGPRGFPGPPGPDGLP 1431 Query: 935 GAQGIMGKPG-DRGPKGERGDQGIPGDRGSQGER 967 G+ G G P D G R Q I + G + Sbjct: 1432 GSMGPPGTPSVDHGFLVTRHSQTIDDPQCPSGTK 1465 Score = 422 bits (1084), Expect = e-117 Identities = 279/682 (40%), Positives = 322/682 (47%), Gaps = 105/682 (15%) Query: 489 GEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEH 548 G KG +GE G+ G QGV G PG GP G G PG KG G G G +G G G G Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102 Query: 549 GIPGKQGIKGEKGDPGGIIGPPGLPG---PKGEAGPPGKSLPGEPGLDGNPGAPGPRGPK 605 G PG GI G+ G PG PPG+PG KGE GP G PG PG GNPG PG G K Sbjct: 103 GNPGLPGIPGQDGPPG----PPGIPGCNGTKGERGPLGP--PGLPGFAGNPGPPGLPGMK 156 Query: 606 GERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPG 665 G+ G H PG + G PG G GP G PG+QGP G PG G PG PG G PG Sbjct: 157 GDPGEILGH-VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPG 215 Query: 666 RDGKPGLP--GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG--K 721 G+ GL GP GD + G G G Q G + KGE+G GEPG Sbjct: 216 EKGQMGLSFQGPKGDKGDQGVSGPPGVP-----GQAQVQEKGDFATKGEKGQKGEPGFQG 270 Query: 722 YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP 781 + KG+ G GP G PG++G KG KG G+PG PG G G QG G G GP GP Sbjct: 271 MPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGP 330 Query: 782 PGLM---------GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIK 832 PG++ G G+PG G +GE G G PG PG PGPPG+P + G + Sbjct: 331 PGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGER 390 Query: 833 GGVNVPSYPGP--PGPPGPKGDPGPVGEPGAMGLPG-----LEGFPGVKGDRGPAGPPGI 885 G +PG PGP G G PGP G PG G PG +E PG GD+GP G PG Sbjct: 391 GEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQ 450 Query: 886 AGMSGKPGAPGPPGVP----------GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPG 935 G G+ G G G G PG +GP G+IGFPG G G G+ G+DG+ G Sbjct: 451 PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAG 510 Query: 936 AQGIMGKPGDRGPKGERGDQG-------IPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988 G G PG G G +G+ G + GD+G G G+PG+TG G+ G G PG Sbjct: 511 VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP 570 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G GSPG G G G PG Sbjct: 571 GPKGSPGSVGLKGERGPPG----------------------------------------- 589 Query: 1049 AAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGS- 1107 G PG G G PGPPG GP G G KG+ G PG PGSPGLPG G PG Sbjct: 590 ---GVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGG--PGSPGLPGPK--GEPGKI 641 Query: 1108 ---PGAPGPQGPPGPSGRCNPE 1126 PG PG +G PG G P+ Sbjct: 642 VPLPGPPGAEGLPGSPGFPGPQ 663 Score = 391 bits (1004), Expect = e-108 Identities = 242/564 (42%), Positives = 278/564 (49%), Gaps = 83/564 (14%) Query: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334 LP K D+ KG+ G G G G G KG G+ G G PG GQ G+ G G Sbjct: 931 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990 Query: 335 SKGETGEKGEQGEKGDP---------ALAGLNGENGLKGDLGPHGPP------GPKGEKG 379 KG+ G G G G P L G GE G+ G GP G P G KGEKG Sbjct: 991 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050 Query: 380 DTGPP--GPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQT 437 GPP G P L G G QG G PG G++G +G G PG PG PG G PG G + Sbjct: 1051 QAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGS 1110 Query: 438 LGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE---PFTKGEKGD- 493 G K +KG + G+ G KGE GLPG PG GP GQKGEPG P + GEKG+ Sbjct: 1111 PGLPGEKGDKGLPGLD--GIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEP 1168 Query: 494 ----RGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHG 549 RG PG G++G KG G+ G PGL GSPG+ G +G G MGP GP G GLPG G Sbjct: 1169 GLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPG 1228 Query: 550 IPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPGPRGPK 605 +G KG++G P G G PGLPGP G G PG K G PG G PG PGP+G Sbjct: 1229 -HATEGPKGDRG-PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDP 1286 Query: 606 GERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPG 665 G +G+PG+ GSP GI G G GP G PG QGP+GLPGL G G G+ GVPG Sbjct: 1287 GFQGMPGIGGSP--------GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPG 1338 Query: 666 RDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSM 725 G PG PGPPG + GEPG Sbjct: 1339 AKGLPGPPGPPGPYDII---------------------------------KGEPGL---- 1361 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLM 785 GP GPPG+ G +G G KG++G G+ G G G+ G G PG G GP G Sbjct: 1362 -----PGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT 1416 Query: 786 GRTGHPGPTGAKGEKGSDGPPGKP 809 G G PGP G G GS GPPG P Sbjct: 1417 GPRGFPGPPGPDGLPGSMGPPGTP 1440 Score = 114 bits (284), Expect = 7e-25 Identities = 74/212 (34%), Positives = 88/212 (41%), Gaps = 77/212 (36%) Query: 941 GKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPG----- 995 GK G KG++G++G+PG +G G GM+G GP GPPG KG G PG Sbjct: 37 GKCDCHGVKGQKGERGLPG------LQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTK 90 Query: 996 -HQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYG 1054 +GPPG+ G PG P G Sbjct: 91 GTRGPPGASGYPGNP--------------------------------------------G 106 Query: 1055 RPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSA--------- 1101 PG PG+DG PGPPG PG G +G++G G PG+ G PG PGLPG Sbjct: 107 LPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHV 166 Query: 1102 --------LGLPGSPGAPGPQGPPGPSGRCNP 1125 G PG PG PGP G PG G P Sbjct: 167 PGMLLKGERGFPGIPGTPGPPGLPGLQGPVGP 198 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 624 bits (1610), Expect = e-178 Identities = 401/955 (41%), Positives = 454/955 (47%), Gaps = 139/955 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG+KGH+G+ G GL G PG G++G+ G G +G GE Sbjct: 469 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 528 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGP 383 KG G G P + G++G G KG LGP G PGP G++G + GP Sbjct: 529 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 588 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 G P LPG G GP G PGKEG G +G GP G GP G PGP G++G+ G + Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKG------EPGEPFTKGEKGD 493 K KG D G+KGD+GE G+PG G GP+G KG +PG P GEKG Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708 Query: 494 RGEPGVIG---SQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGI 550 G PG+ G QG KG G PG PG G G +G G +G G RGP G G G G Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768 Query: 551 PGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGE 607 GK G KG G G G G GLPGP+G G PG K PG PG DG PG PG RG G Sbjct: 769 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 828 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD 667 +G G G PG +GPQG G TG G G PG GP G GLPGT G G G PG Sbjct: 829 QGKTGPPGPPGVVGPQGAA--GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886 Query: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNC----QASVPGLKSNKGEEGGAGEPGKYD 723 G PG GP G L+ F G A PGLK N+G G G G Sbjct: 887 GAPGKDGPAG--------------LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 932 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 G GP GPPG PG +GP G+ GE+G PG G G G G+ G G PGP GPPG Sbjct: 933 ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 992 Query: 784 LMGR------TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYK 830 + G G PG G KG KG GPPG PGP GP G P G + Sbjct: 993 VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1052 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG 890 KG + GPPGP G +G PGP GE G G G G PG G RGPAGP G G G Sbjct: 1053 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1112 Query: 891 KPGAPG---PPGVPGEPGE------------------RGPVGDIGFPGPEGPSGKPGING 929 PG G PPG GEPGE RG G+ G PG GP G G G Sbjct: 1113 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1172 Query: 930 KDGIPGAQGIMGKPGDRGPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 DG G G +G PGD GP GE RG G GDRG GE G+PG G G GP GP G Sbjct: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1232 Query: 987 NKGSMGSPGHQG---------PPGSPGIPGIPADAVSFEEIKKYINQEVLR-----IFEE 1032 +G GSPG +G PG+ G PG K + LR + ++ Sbjct: 1233 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-GPDGLRGLPGSVGQQ 1291 Query: 1033 RMAVFLSQLK---------LPAAMLAAQAYGRPGPPGKDGLPGPPGD---------PGPQ 1074 Q LP A A G G PG GL GPPG+ PGPQ Sbjct: 1292 GRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1351 Query: 1075 GYRGQKGERGEPG----IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G GQKGE G PG IG G PGLPG + G G+ GA GP GP G G P Sbjct: 1352 GSPGQKGEMGIPGASGPIGPGGPPGLPGPA--GPKGAKGATGPGGPKGEKGVQGP 1404 Score = 615 bits (1587), Expect = e-176 Identities = 399/983 (40%), Positives = 464/983 (47%), Gaps = 148/983 (15%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P LK + + +G G G G PG+ G +G G +G G PG PG KG++GF+G Sbjct: 418 PGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 477 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALP-- 390 G GEKG +G+ G L G GE+G +GD +GP G PG G +G GP GPP +P Sbjct: 478 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 537 Query: 391 -------------GSLGIQGPQGPPGKE------------------GQRGRRGKTGPPGK 419 GSLG QG GPPG++ G++G +GK G PG Sbjct: 538 PGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM 597 Query: 420 PGPPGPPGPPGIQGIHQTLG-----------GYYN-KDNKGNDE-HEAGGLKGDKGETGL 466 PG GPPG PG +G T G GY + KG D G KG+KGE G Sbjct: 598 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 657 Query: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS------ 520 PGF G +G KG +GE G P G RGE G G +G G GDPGPPGL+G Sbjct: 658 PGFKGDIGVKGDRGEVGVP------GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 711 Query: 521 ---PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----------GI 566 PG G+QG GS+G G PG G G G+ GK G +GE+G G G Sbjct: 712 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 771 Query: 567 IGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 G G G G GPPG + LPG G +G PG GP GP G+ GLPG G G++G QG Sbjct: 772 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK 831 Query: 625 IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684 G PG G GP G G GP G G PG PG PG G+PG GK G G PG P A Sbjct: 832 TGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 891 Query: 685 LGDIGALLKNFCGN----CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIP 740 G G L+ F G A PGLK N+G G G G G GP GPPG P Sbjct: 892 DGPAG--LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 949 Query: 741 GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL------MGRTGHPGPT 794 G +GP G+ GE+G PG G G G G+ G G PGP GPPG+ G G PG Sbjct: 950 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1009 Query: 795 GAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYKIKGGVNVPSYPGPPGPP 847 G KG KG GPPG PGP GP G P G + KG + GPPGP Sbjct: 1010 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1069 Query: 848 GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGI---------------------A 886 G +G PGP GE G G G G PG G RGPAGP G Sbjct: 1070 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1129 Query: 887 GMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDR 946 G SG PG G PGV G GERG G+ G PG GP G G G DG G G +G PGD Sbjct: 1130 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1189 Query: 947 GPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSP 1003 GP GE RG G GDRG GE G+PG G G GP GP G +G GSPG +G G Sbjct: 1190 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1249 Query: 1004 GIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDG 1063 G G P A+ + + A L + GRPG G+ G Sbjct: 1250 GAKGDPG-AIG-------APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG 1301 Query: 1064 LPGPPGDPGPQGYRGQ---KGERGEPGI----------------GLPGSPGLPGTSA-LG 1103 PGP G PG G RG KGE+G PG+ GLPG G PG +G Sbjct: 1302 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1361 Query: 1104 LPGSPGAPGPQGPPGPSGRCNPE 1126 +PG+ G GP GPPG G P+ Sbjct: 1362 IPGASGPIGPGGPPGLPGPAGPK 1384 Score = 600 bits (1548), Expect = e-171 Identities = 434/1262 (34%), Positives = 549/1262 (43%), Gaps = 263/1262 (20%) Query: 59 LGDSFSLRRAFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWF 118 L D + C +D A L T ++FP G P+++S+ + R R + Sbjct: 43 LPDGVRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAP--- 99 Query: 119 LWQVLNQQNIPQISIVVDGGKKVVEFMFQATEG---DVLNYIFRNRELRPLFDRQWHKLG 175 L + + Q + Q+ + + + V F+++ G +FR L D +WH++ Sbjct: 100 LLTLYSAQGVRQLGLELG---RPVRFLYEDQTGRPQPPSQPVFRGLSLA---DGKWHRVA 153 Query: 176 ISIQSQVISLYMDCNLIARRQTDE--KDTVDFHGRTVIATRASDGKPVDIELHQLKIYCS 233 ++++ Q ++L +DC R + +D HG + R D + + ++ +L I Sbjct: 154 VAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPG 213 Query: 234 ANLIAQETCCEISDTKCP--EQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNK 291 A CE + +C +++ N + S L Q + Q Q P Sbjct: 214 VQ--AAYESCEQKELECEGGQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQD-PTP 270 Query: 292 GEAG-------LP----GAPGSPGQKGHKGEPG--ENGL--HGAPGFPGQKGEQGFEGSK 336 GE LP A G G KG KGEP E G+ G PG G G G G + Sbjct: 271 GEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 330 Query: 337 GETGEKGEQGEKGDPALAGLNGENGLK-----------------GDLGP----------- 368 G G G+ GE+G P AGL G +G GD GP Sbjct: 331 GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 390 Query: 369 ---------HGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGK 419 GPPGP G TG PGP PGS G++G G G +G RG +G TGPPGK Sbjct: 391 ILQQARLALRGPPGPMGY---TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447 Query: 420 PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQK 479 G G G G +G+ G+ G+KGD+G GLPG PG G +G Sbjct: 448 AGRRGRAGADGARGM------------PGDP-----GVKGDRGFDGLPGLPGEKGHRGDT 490 Query: 480 GEPGEPFTKGEKGDRGEPGVIGSQGV------------KGEPGDPGPPGLIGSPGLKGQQ 527 G G P GE G+RG+ G IG +G+ KG PG PGPPG+ G G +G + Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550 Query: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-KSL 586 GS G G GPPG G PG G+PG QG G G+ G G PGLPG G GPPG Sbjct: 551 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP-QGKPGLPGMPGSDGPPGHPGK 609 Query: 587 PGEPGLDGNPGAPGPRGP---------------------KGERGLPGVHGSPGDIGPQG- 624 G PG GN G GP+GP KGE+G G G GDIG +G Sbjct: 610 EGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGD 669 Query: 625 ---IGIP------------GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK 669 +G+P GRTG G G PG+ G +G G+PG PG PG G G G Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729 Query: 670 PGLPGPPGDPIALPLLGDIGALLKN--FCGNCQASVPGLKSNKGEEGGAGEPGKYDSMAR 727 PG PG G+ A L G G + Q G G +G +G G + Sbjct: 730 PGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 789 Query: 728 KGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL--- 784 +G GP+GP G PG +GP G G+ G PG PG++G+ G QG G PG PG GP G Sbjct: 790 RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGE 849 Query: 785 ---MGRTGHPGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNER-------NGMSSLYKI 831 MG GHPGP G GE+G G GK G PGPPG P + G L Sbjct: 850 TGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGT 909 Query: 832 KGGVNVPSYPGPPGPPGPKGDP------------GPVGEPGAMGLPGLEGFPGVKGDRGP 879 GG + GP GPPGP G P GP G PG G PG G GV G++GP Sbjct: 910 AGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969 Query: 880 AGP---PGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGF---------------PGPEGP 921 GP G+ G G PG GPPGV GE G++G VGD G PGP GP Sbjct: 970 IGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGP 1029 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD---------QGIPGDRGSQGER----- 967 G+PG G DG PGA+G G G +G +G RG QG+PG G +GE Sbjct: 1030 VGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGP 1089 Query: 968 -------GKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 G G G GA GP GPPG G++G PG +G PG G PGI + Sbjct: 1090 MGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE--------- 1140 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 +K P G G G+ G PG PG PGP+G G Sbjct: 1141 ------------------PGVKGPR--------GERGEKGESGQPGEPGPPGPKGPTGDD 1174 Query: 1081 GERGEPG-IGLPGSPGLPGTSAL-------------GLPGSPGAPGP---QGPPGPSGRC 1123 G +G PG +G PG PG PG G PG PG+PGP GPPGP G+ Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234 Query: 1124 NP 1125 P Sbjct: 1235 GP 1236 Score = 573 bits (1476), Expect = e-163 Identities = 366/883 (41%), Positives = 422/883 (47%), Gaps = 137/883 (15%) Query: 291 KGEAGLPGAPGSPGQKGH---------KGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 +G+ GLPG PGS G GH KG G +G G G+PG +G +G +G +G G Sbjct: 589 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 648 Query: 342 KGEQGE------KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL------ 389 KGE+GE KGD + G GE G+ G G GP GPKG G TG PGPP L Sbjct: 649 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 708 Query: 390 ------PGSLGIQGPQGP------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQT 437 PG G QGP+G PG G++G RG +G G G GP GP G +G Sbjct: 709 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 768 Query: 438 LGGYYNKDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G K G D GL G +G G PG G GP G+ G PG P +GE G Sbjct: 769 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 828 Query: 494 RGE------PGVIGSQGVKGE---------PGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538 +G+ PGV+G QG GE PG PGPPG G PG G++G+ G GP G Sbjct: 829 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888 Query: 539 PGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNP 596 PG G G G PG++G+ G G PG G GP G PGP G G G + G G G P Sbjct: 889 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA--GSGGPIGPP 946 Query: 597 GAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGI---QGPRGLPGLP 652 G PGP+GP G G GV G G IGP G G+ G G GPAG PG+ G +G G P Sbjct: 947 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1006 Query: 653 GTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGAL--LKNFCGNCQASVPGLKSNK 710 G GT GN G G G PG GP G P A G+ GA +F G Sbjct: 1007 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066 Query: 711 GEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIP 770 G G G PG GD+GP GPPG PG GP G G G G PG G+ G P Sbjct: 1067 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN---LGPP 1123 Query: 771 GIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYK 830 G G PG +G PG+ G G GP G +GEKG G PG+PGPPGP G P + + Sbjct: 1124 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG-PTGDDGPKGN--- 1179 Query: 831 IKGGVNVPSYPGPPGPPGP------KGDPGPVGEPGAMGLPGLEGF---PGVKGDRGPAG 881 G V P PGPPG GP KGD G GEPG G PG G PG G RGPAG Sbjct: 1180 -PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1238 Query: 882 PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941 PG G G GA G PG G PG+ GPVG P GP+GKPG +G G+PG+ G G Sbjct: 1239 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPDGLRGLPGSVGQQG 1292 Query: 942 KPG---DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 +PG GP G G G+PG RG G +G+ G G+ G IGP G G KG G PG QG Sbjct: 1293 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1352 Query: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 PG G GIP A G GP Sbjct: 1353 SPGQKGEMGIPG-----------------------------------------ASGPIGP 1371 Query: 1059 PGKDGLPGPPGDPG------PQGYRGQKGERGEPGIGLPGSPG 1095 G GLPGP G G P G +G+KG +G P G PG PG Sbjct: 1372 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP--GHPGPPG 1412 Score = 311 bits (797), Expect = 2e-84 Identities = 213/562 (37%), Positives = 254/562 (45%), Gaps = 108/562 (19%) Query: 598 APGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657 A GPRG KGE+G P V PG + G PG G G G PGIQG G G PG G Sbjct: 289 AHGPRGLKGEKGEPAVL-EPGMLVE---GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 344 Query: 658 PGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGG-- 715 PG G+PG DG PG PPG + LP G G++G Sbjct: 345 PGRAGLPGSDGAPG---PPGTSLMLPFRFGSGG--------------------GDKGPVV 381 Query: 716 AGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGA 775 A + + ++ ++ + RGPPG G G G G+ G PG+ GE GD G QG G G Sbjct: 382 AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 441 Query: 776 PGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGV 835 TGPPG GR G G GA+G G G G G G PG+P + + +G Sbjct: 442 ---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH--------RGDT 490 Query: 836 NVPSYPGPPGPPGPKGDPGPVG------EPGAMGL------PGLEGFPGVKGDRGPAGPP 883 PGPPG G +GD G +G E G GL PG+ G PGV+G GP GP Sbjct: 491 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 550 Query: 884 GIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI------NGKDGIPGAQ 937 G G G+PG PG G PG G GP G IG G +GP GKPG+ +G G PG + Sbjct: 551 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 610 Query: 938 GIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ 997 G G G++GP G +G G PG RG +G G GL G KG G G PG KG +G G + Sbjct: 611 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 670 Query: 998 GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPG 1057 G G PG + G G Sbjct: 671 GEVGVPG-----------------------------------------------SRGEDG 683 Query: 1058 PPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTS-ALGLPGSPGAPGPQGP 1116 P G G GP GDPGP G G+KG+ G PG LPG PG G +LG PG PGA G +G Sbjct: 684 PEGPKGRTGPTGDPGPPGLMGEKGKLGVPG--LPGYPGRQGPKGSLGFPGFPGASGEKGA 741 Query: 1117 PGPSGRCNPEDCLYPVSHAHQR 1138 G SG+ P P QR Sbjct: 742 RGLSGKSGPRGERGPTGPRGQR 763 Score = 287 bits (735), Expect = 3e-77 Identities = 173/387 (44%), Positives = 206/387 (53%), Gaps = 36/387 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KGE G G G PG G +G G NG G G PG G G G KGE GE G G +G+ Sbjct: 1081 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1140 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 P + G GE G KG+ G G PGP G KG TG GP PG +G G GPPG+ G RG+ Sbjct: 1141 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1200 Query: 411 ------RGKTGPPGKPGPPGP---PGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-GLKGD 460 RG+ G PG+PG PGP GPPG G G + G++ + G G KGD Sbjct: 1201 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG------SPGSEGRQGGKGAKGD 1254 Query: 461 KGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS 520 G G PG G VGP G G+P G G RG PG +G QG G G GPPG +G Sbjct: 1255 PGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP 1308 Query: 521 PGLKGQQGSAGSMGPRGPPGDVGL---PGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGP 575 PGL G +G AG+ G +G PG +GL PGE G G +G+ G +G PG G +G PG GP Sbjct: 1309 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1368 Query: 576 KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIG----PQGIGIPGRT 631 G GPPG LPG G G GA GP GPKGE+G+ G G PG G P I +P +T Sbjct: 1369 IGPGGPPG--LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1426 Query: 632 GAQGPAGEPGIQGPRGLP--GLPGTPG 656 + G +Q +P G PG+PG Sbjct: 1427 -RRSVDGSRLMQEDEAIPTGGAPGSPG 1452 Score = 203 bits (516), Expect = 9e-52 Identities = 138/333 (41%), Positives = 157/333 (47%), Gaps = 59/333 (17%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 N G G PG PG PG+ G +G+ G G G G PGQ G G G G G G++G G Sbjct: 1179 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1238 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 P G G G KGD G G PG G G GP G P G G +G PG GQ+G Sbjct: 1239 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQG 1292 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 R G TG G PGP GPPG PG++G +AG KGE G PG Sbjct: 1293 RPGATGQAGPPGPVGPPGLPGLRG-------------------DAGA----KGEKGHPGL 1329 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529 G +GP G+ +GEKGDRG PG GS G KGE G PG G IG PG G Sbjct: 1330 IGLIGPPGE---------QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG-PG-----GP 1374 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G GP GP G G G PG G KGEK G+ GPPG PGP GE P LP + Sbjct: 1375 PGLPGPAGPKGAKGATG----PG--GPKGEK----GVQGPPGHPGPPGEVIQP---LPIQ 1421 Query: 590 PGLDGNPGAPGPRGPKGERGLP--GVHGSPGDI 620 G R + + +P G GSPG + Sbjct: 1422 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGL 1454 Score = 144 bits (364), Expect = 4e-34 Identities = 102/282 (36%), Positives = 125/282 (44%), Gaps = 61/282 (21%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 ++GE G PG PGSPG G G PG G G G PG +G QG +G+KG+ G G G+ G Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265 Query: 350 DPALAGLNGE------NGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG------------ 391 AG G+ GL G +G G PG G+ G GP GPP LPG Sbjct: 1266 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1325 Query: 392 ------------------SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G+ GPQG PG++G+ G G +GP G GPPG PGP G +G Sbjct: 1326 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG 1385 Query: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G GG KG+KG G PG P GP G+ +P P +K Sbjct: 1386 AKGATG--------------PGGPKGEKGVQGPPGHP---GPPGEVIQP-LPIQMPKKTR 1427 Query: 494 RGEPGVIGSQGVKGEP--GDPGPPGLIGSPGLKGQQGSAGSM 533 R G Q + P G PG PG GL+ GS S+ Sbjct: 1428 RSVDGSRLMQEDEAIPTGGAPGSPG-----GLEEIFGSLDSL 1464 Score = 109 bits (272), Expect = 2e-23 Identities = 65/153 (42%), Positives = 78/153 (50%), Gaps = 16/153 (10%) Query: 276 PAKQELKDQCQCIPNK-GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334 PA + D + +P G+ G PGA G G G G PG GL G G G+KG G G Sbjct: 1272 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1331 Query: 335 ---SKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG 391 GE GEKG++G L G G G KG++G G GP GP GPP LPG Sbjct: 1332 LIGPPGEQGEKGDRG------LPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPG 1379 Query: 392 SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG 424 G +G +G G G +G +G GPPG PGPPG Sbjct: 1380 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1412 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 624 bits (1610), Expect = e-178 Identities = 401/955 (41%), Positives = 454/955 (47%), Gaps = 139/955 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG+KGH+G+ G GL G PG G++G+ G G +G GE Sbjct: 448 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 507 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGP 383 KG G G P + G++G G KG LGP G PGP G++G + GP Sbjct: 508 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 567 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 G P LPG G GP G PGKEG G +G GP G GP G PGP G++G+ G + Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKG------EPGEPFTKGEKGD 493 K KG D G+KGD+GE G+PG G GP+G KG +PG P GEKG Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687 Query: 494 RGEPGVIG---SQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGI 550 G PG+ G QG KG G PG PG G G +G G +G G RGP G G G G Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747 Query: 551 PGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGE 607 GK G KG G G G G GLPGP+G G PG K PG PG DG PG PG RG G Sbjct: 748 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 807 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD 667 +G G G PG +GPQG G TG G G PG GP G GLPGT G G G PG Sbjct: 808 QGKTGPPGPPGVVGPQGAA--GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865 Query: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNC----QASVPGLKSNKGEEGGAGEPGKYD 723 G PG GP G L+ F G A PGLK N+G G G G Sbjct: 866 GAPGKDGPAG--------------LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 911 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 G GP GPPG PG +GP G+ GE+G PG G G G G+ G G PGP GPPG Sbjct: 912 ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 971 Query: 784 LMGR------TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYK 830 + G G PG G KG KG GPPG PGP GP G P G + Sbjct: 972 VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1031 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG 890 KG + GPPGP G +G PGP GE G G G G PG G RGPAGP G G G Sbjct: 1032 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1091 Query: 891 KPGAPG---PPGVPGEPGE------------------RGPVGDIGFPGPEGPSGKPGING 929 PG G PPG GEPGE RG G+ G PG GP G G G Sbjct: 1092 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1151 Query: 930 KDGIPGAQGIMGKPGDRGPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 DG G G +G PGD GP GE RG G GDRG GE G+PG G G GP GP G Sbjct: 1152 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1211 Query: 987 NKGSMGSPGHQG---------PPGSPGIPGIPADAVSFEEIKKYINQEVLR-----IFEE 1032 +G GSPG +G PG+ G PG K + LR + ++ Sbjct: 1212 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-GPDGLRGLPGSVGQQ 1270 Query: 1033 RMAVFLSQLK---------LPAAMLAAQAYGRPGPPGKDGLPGPPGD---------PGPQ 1074 Q LP A A G G PG GL GPPG+ PGPQ Sbjct: 1271 GRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1330 Query: 1075 GYRGQKGERGEPG----IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G GQKGE G PG IG G PGLPG + G G+ GA GP GP G G P Sbjct: 1331 GSPGQKGEMGIPGASGPIGPGGPPGLPGPA--GPKGAKGATGPGGPKGEKGVQGP 1383 Score = 615 bits (1587), Expect = e-176 Identities = 399/983 (40%), Positives = 464/983 (47%), Gaps = 148/983 (15%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P LK + + +G G G G PG+ G +G G +G G PG PG KG++GF+G Sbjct: 397 PGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 456 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALP-- 390 G GEKG +G+ G L G GE+G +GD +GP G PG G +G GP GPP +P Sbjct: 457 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 516 Query: 391 -------------GSLGIQGPQGPPGKE------------------GQRGRRGKTGPPGK 419 GSLG QG GPPG++ G++G +GK G PG Sbjct: 517 PGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM 576 Query: 420 PGPPGPPGPPGIQGIHQTLG-----------GYYN-KDNKGNDE-HEAGGLKGDKGETGL 466 PG GPPG PG +G T G GY + KG D G KG+KGE G Sbjct: 577 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 636 Query: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS------ 520 PGF G +G KG +GE G P G RGE G G +G G GDPGPPGL+G Sbjct: 637 PGFKGDIGVKGDRGEVGVP------GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 690 Query: 521 ---PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----------GI 566 PG G+QG GS+G G PG G G G+ GK G +GE+G G G Sbjct: 691 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 750 Query: 567 IGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 G G G G GPPG + LPG G +G PG GP GP G+ GLPG G G++G QG Sbjct: 751 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK 810 Query: 625 IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684 G PG G GP G G GP G G PG PG PG G+PG GK G G PG P A Sbjct: 811 TGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 870 Query: 685 LGDIGALLKNFCGN----CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIP 740 G G L+ F G A PGLK N+G G G G G GP GPPG P Sbjct: 871 DGPAG--LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928 Query: 741 GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL------MGRTGHPGPT 794 G +GP G+ GE+G PG G G G G+ G G PGP GPPG+ G G PG Sbjct: 929 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988 Query: 795 GAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYKIKGGVNVPSYPGPPGPP 847 G KG KG GPPG PGP GP G P G + KG + GPPGP Sbjct: 989 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1048 Query: 848 GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGI---------------------A 886 G +G PGP GE G G G G PG G RGPAGP G Sbjct: 1049 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1108 Query: 887 GMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDR 946 G SG PG G PGV G GERG G+ G PG GP G G G DG G G +G PGD Sbjct: 1109 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1168 Query: 947 GPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSP 1003 GP GE RG G GDRG GE G+PG G G GP GP G +G GSPG +G G Sbjct: 1169 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1228 Query: 1004 GIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDG 1063 G G P A+ + + A L + GRPG G+ G Sbjct: 1229 GAKGDPG-AIG-------APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG 1280 Query: 1064 LPGPPGDPGPQGYRGQ---KGERGEPGI----------------GLPGSPGLPGTSA-LG 1103 PGP G PG G RG KGE+G PG+ GLPG G PG +G Sbjct: 1281 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1340 Query: 1104 LPGSPGAPGPQGPPGPSGRCNPE 1126 +PG+ G GP GPPG G P+ Sbjct: 1341 IPGASGPIGPGGPPGLPGPAGPK 1363 Score = 602 bits (1553), Expect = e-172 Identities = 428/1249 (34%), Positives = 543/1249 (43%), Gaps = 258/1249 (20%) Query: 59 LGDSFSLRRAFCESDKTCFKLGSALLIRDTIKIFPKGLPEEYSVAAMFRVRRNAKKERWF 118 L D + C +D A L T ++FP G P+++S+ + R R + Sbjct: 43 LPDGVRRAKGICPADVAYRVARPAQLSAPTRQLFPGGFPKDFSLLTVVRTRPGLQAP--- 99 Query: 119 LWQVLNQQNIPQISIVVDGGKKVVEFMFQATEG---DVLNYIFRNRELRPLFDRQWHKLG 175 L + + Q + Q+ + + + V F+++ G +FR L D +WH++ Sbjct: 100 LLTLYSAQGVRQLGLELG---RPVRFLYEDQTGRPQPPSQPVFRGLSLA---DGKWHRVA 153 Query: 176 ISIQSQVISLYMDCNLIARRQTDE--KDTVDFHGRTVIATRASDGKPVDIELHQLKIYCS 233 ++++ Q ++L +DC R + +D HG + R D + + ++ +L I Sbjct: 154 VAVKGQSVTLIVDCKKRVTRPLPRSARPVLDTHGVIIFGARILDEEVFEGDVQELAIVPG 213 Query: 234 ANLIAQETCCEISDTKCPEQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGE 293 A CE + +C + G + A + P++ P E Sbjct: 214 VQ--AAYESCEQKELEC--EGGQRERPQNQQPHRAQRSPQQQPSRLHR-------PQNQE 262 Query: 294 AGLPGAPGSPGQKGHKGEPG--ENGL--HGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 A G G KG KGEP E G+ G PG G G G G +G G G+ GE+G Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322 Query: 350 DPALAGLNGENGLK-----------------GDLGP--------------------HGPP 372 P AGL G +G GD GP GPP Sbjct: 323 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382 Query: 373 GPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQ 432 GP G TG PGP PGS G++G G G +G RG +G TGPPGK G G G G + Sbjct: 383 GPMGY---TGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 439 Query: 433 GIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 G+ G+ G+KGD+G GLPG PG G +G G G P GE G Sbjct: 440 GM------------PGDP-----GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDG 482 Query: 493 DRGEPGVIGSQGV------------KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG 540 +RG+ G IG +G+ KG PG PGPPG+ G G +G +GS G G GPPG Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542 Query: 541 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAP 599 G PG G+PG QG G G+ G G PGLPG G GPPG G PG GN G Sbjct: 543 QQGTPGTQGLPGPQGAIGPHGEKGP-QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 601 Query: 600 GPRGP---------------------KGERGLPGVHGSPGDIGPQG----IGIP------ 628 GP+GP KGE+G G G GDIG +G +G+P Sbjct: 602 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED 661 Query: 629 ------GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIAL 682 GRTG G G PG+ G +G G+PG PG PG G G G PG PG G+ A Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 721 Query: 683 PLLGDIGALLKN--FCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIP 740 L G G + Q G G +G +G G + +G GP+GP G P Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781 Query: 741 GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL------MGRTGHPGPT 794 G +GP G G+ G PG PG++G+ G QG G PG PG GP G MG GHPGP Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPP 841 Query: 795 GAKGEKGSDGPPGK---PGPPGPPGIPFNER-------NGMSSLYKIKGGVNVPSYPGPP 844 G GE+G G GK G PGPPG P + G L GG + GP Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPS 901 Query: 845 GPPGPKGDP------------GPVGEPGAMGLPGLEGFPGVKGDRGPAGP---PGIAGMS 889 GPPGP G P GP G PG G PG G GV G++GP GP G+ G Sbjct: 902 GPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV 961 Query: 890 GKPGAPGPPGVPGEPGERGPVGDIGF---------------PGPEGPSGKPGINGKDGIP 934 G PG GPPGV GE G++G VGD G PGP GP G+PG G DG P Sbjct: 962 GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP 1021 Query: 935 GAQGIMGKPGDRGPKGERGD---------QGIPGDRGSQGER------------GKPGLT 973 GA+G G G +G +G RG QG+PG G +GE G G Sbjct: 1022 GARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPA 1081 Query: 974 GMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 G GA GP GPPG G++G PG +G PG G PGI + Sbjct: 1082 GPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE---------------------- 1119 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPG 1092 +K P G G G+ G PG PG PGP+G G G +G PG +G PG Sbjct: 1120 -----PGVKGPR--------GERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166 Query: 1093 SPGLPGTSAL-------------GLPGSPGAPGP---QGPPGPSGRCNP 1125 PG PG G PG PG+PGP GPPGP G+ P Sbjct: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGP 1215 Score = 573 bits (1476), Expect = e-163 Identities = 366/883 (41%), Positives = 422/883 (47%), Gaps = 137/883 (15%) Query: 291 KGEAGLPGAPGSPGQKGH---------KGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 +G+ GLPG PGS G GH KG G +G G G+PG +G +G +G +G G Sbjct: 568 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 627 Query: 342 KGEQGE------KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL------ 389 KGE+GE KGD + G GE G+ G G GP GPKG G TG PGPP L Sbjct: 628 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 687 Query: 390 ------PGSLGIQGPQGP------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQT 437 PG G QGP+G PG G++G RG +G G G GP GP G +G Sbjct: 688 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 747 Query: 438 LGGYYNKDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G K G D GL G +G G PG G GP G+ G PG P +GE G Sbjct: 748 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 807 Query: 494 RGE------PGVIGSQGVKGE---------PGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538 +G+ PGV+G QG GE PG PGPPG G PG G++G+ G GP G Sbjct: 808 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 867 Query: 539 PGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNP 596 PG G G G PG++G+ G G PG G GP G PGP G G G + G G G P Sbjct: 868 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA--GSGGPIGPP 925 Query: 597 GAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGI---QGPRGLPGLP 652 G PGP+GP G G GV G G IGP G G+ G G GPAG PG+ G +G G P Sbjct: 926 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 985 Query: 653 GTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGAL--LKNFCGNCQASVPGLKSNK 710 G GT GN G G G PG GP G P A G+ GA +F G Sbjct: 986 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045 Query: 711 GEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIP 770 G G G PG GD+GP GPPG PG GP G G G G PG G+ G P Sbjct: 1046 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN---LGPP 1102 Query: 771 GIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYK 830 G G PG +G PG+ G G GP G +GEKG G PG+PGPPGP G P + + Sbjct: 1103 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG-PTGDDGPKGN--- 1158 Query: 831 IKGGVNVPSYPGPPGPPGP------KGDPGPVGEPGAMGLPGLEGF---PGVKGDRGPAG 881 G V P PGPPG GP KGD G GEPG G PG G PG G RGPAG Sbjct: 1159 -PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1217 Query: 882 PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941 PG G G GA G PG G PG+ GPVG P GP+GKPG +G G+PG+ G G Sbjct: 1218 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPDGLRGLPGSVGQQG 1271 Query: 942 KPG---DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 +PG GP G G G+PG RG G +G+ G G+ G IGP G G KG G PG QG Sbjct: 1272 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1331 Query: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 PG G GIP A G GP Sbjct: 1332 SPGQKGEMGIPG-----------------------------------------ASGPIGP 1350 Query: 1059 PGKDGLPGPPGDPG------PQGYRGQKGERGEPGIGLPGSPG 1095 G GLPGP G G P G +G+KG +G P G PG PG Sbjct: 1351 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP--GHPGPPG 1391 Score = 311 bits (797), Expect = 2e-84 Identities = 213/562 (37%), Positives = 254/562 (45%), Gaps = 108/562 (19%) Query: 598 APGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGT 657 A GPRG KGE+G P V PG + G PG G G G PGIQG G G PG G Sbjct: 268 AHGPRGLKGEKGEPAVL-EPGMLVE---GPPGPEGPAGLIGPPGIQGNPGPVGDPGERGP 323 Query: 658 PGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGG-- 715 PG G+PG DG PG PPG + LP G G++G Sbjct: 324 PGRAGLPGSDGAPG---PPGTSLMLPFRFGSGG--------------------GDKGPVV 360 Query: 716 AGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGA 775 A + + ++ ++ + RGPPG G G G G+ G PG+ GE GD G QG G G Sbjct: 361 AAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGL 420 Query: 776 PGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGV 835 TGPPG GR G G GA+G G G G G G PG+P + + +G Sbjct: 421 ---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH--------RGDT 469 Query: 836 NVPSYPGPPGPPGPKGDPGPVG------EPGAMGL------PGLEGFPGVKGDRGPAGPP 883 PGPPG G +GD G +G E G GL PG+ G PGV+G GP GP Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529 Query: 884 GIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI------NGKDGIPGAQ 937 G G G+PG PG G PG G GP G IG G +GP GKPG+ +G G PG + Sbjct: 530 GSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKE 589 Query: 938 GIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ 997 G G G++GP G +G G PG RG +G G GL G KG G G PG KG +G G + Sbjct: 590 GPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDR 649 Query: 998 GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPG 1057 G G PG + G G Sbjct: 650 GEVGVPG-----------------------------------------------SRGEDG 662 Query: 1058 PPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTS-ALGLPGSPGAPGPQGP 1116 P G G GP GDPGP G G+KG+ G PG LPG PG G +LG PG PGA G +G Sbjct: 663 PEGPKGRTGPTGDPGPPGLMGEKGKLGVPG--LPGYPGRQGPKGSLGFPGFPGASGEKGA 720 Query: 1117 PGPSGRCNPEDCLYPVSHAHQR 1138 G SG+ P P QR Sbjct: 721 RGLSGKSGPRGERGPTGPRGQR 742 Score = 287 bits (735), Expect = 3e-77 Identities = 173/387 (44%), Positives = 206/387 (53%), Gaps = 36/387 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KGE G G G PG G +G G NG G G PG G G G KGE GE G G +G+ Sbjct: 1060 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1119 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 P + G GE G KG+ G G PGP G KG TG GP PG +G G GPPG+ G RG+ Sbjct: 1120 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1179 Query: 411 ------RGKTGPPGKPGPPGP---PGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-GLKGD 460 RG+ G PG+PG PGP GPPG G G + G++ + G G KGD Sbjct: 1180 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG------SPGSEGRQGGKGAKGD 1233 Query: 461 KGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS 520 G G PG G VGP G G+P G G RG PG +G QG G G GPPG +G Sbjct: 1234 PGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP 1287 Query: 521 PGLKGQQGSAGSMGPRGPPGDVGL---PGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGP 575 PGL G +G AG+ G +G PG +GL PGE G G +G+ G +G PG G +G PG GP Sbjct: 1288 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1347 Query: 576 KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIG----PQGIGIPGRT 631 G GPPG LPG G G GA GP GPKGE+G+ G G PG G P I +P +T Sbjct: 1348 IGPGGPPG--LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1405 Query: 632 GAQGPAGEPGIQGPRGLP--GLPGTPG 656 + G +Q +P G PG+PG Sbjct: 1406 -RRSVDGSRLMQEDEAIPTGGAPGSPG 1431 Score = 203 bits (516), Expect = 9e-52 Identities = 138/333 (41%), Positives = 157/333 (47%), Gaps = 59/333 (17%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 N G G PG PG PG+ G +G+ G G G G PGQ G G G G G G++G G Sbjct: 1158 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1217 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 P G G G KGD G G PG G G GP G P G G +G PG GQ+G Sbjct: 1218 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQG 1271 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 R G TG G PGP GPPG PG++G +AG KGE G PG Sbjct: 1272 RPGATGQAGPPGPVGPPGLPGLRG-------------------DAGA----KGEKGHPGL 1308 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529 G +GP G+ +GEKGDRG PG GS G KGE G PG G IG PG G Sbjct: 1309 IGLIGPPGE---------QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG-PG-----GP 1353 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G GP GP G G G PG G KGEK G+ GPPG PGP GE P LP + Sbjct: 1354 PGLPGPAGPKGAKGATG----PG--GPKGEK----GVQGPPGHPGPPGEVIQP---LPIQ 1400 Query: 590 PGLDGNPGAPGPRGPKGERGLP--GVHGSPGDI 620 G R + + +P G GSPG + Sbjct: 1401 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGL 1433 Score = 144 bits (364), Expect = 4e-34 Identities = 102/282 (36%), Positives = 125/282 (44%), Gaps = 61/282 (21%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 ++GE G PG PGSPG G G PG G G G PG +G QG +G+KG+ G G G+ G Sbjct: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244 Query: 350 DPALAGLNGE------NGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG------------ 391 AG G+ GL G +G G PG G+ G GP GPP LPG Sbjct: 1245 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1304 Query: 392 ------------------SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G+ GPQG PG++G+ G G +GP G GPPG PGP G +G Sbjct: 1305 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG 1364 Query: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G GG KG+KG G PG P GP G+ +P P +K Sbjct: 1365 AKGATG--------------PGGPKGEKGVQGPPGHP---GPPGEVIQP-LPIQMPKKTR 1406 Query: 494 RGEPGVIGSQGVKGEP--GDPGPPGLIGSPGLKGQQGSAGSM 533 R G Q + P G PG PG GL+ GS S+ Sbjct: 1407 RSVDGSRLMQEDEAIPTGGAPGSPG-----GLEEIFGSLDSL 1443 Score = 109 bits (272), Expect = 2e-23 Identities = 65/153 (42%), Positives = 78/153 (50%), Gaps = 16/153 (10%) Query: 276 PAKQELKDQCQCIPNK-GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334 PA + D + +P G+ G PGA G G G G PG GL G G G+KG G G Sbjct: 1251 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1310 Query: 335 ---SKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG 391 GE GEKG++G L G G G KG++G G GP GP GPP LPG Sbjct: 1311 LIGPPGEQGEKGDRG------LPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPG 1358 Query: 392 SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG 424 G +G +G G G +G +G GPPG PGPPG Sbjct: 1359 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1391 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 624 bits (1610), Expect = e-178 Identities = 401/955 (41%), Positives = 454/955 (47%), Gaps = 139/955 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG+KGH+G+ G GL G PG G++G+ G G +G GE Sbjct: 555 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGP 614 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGP 383 KG G G P + G++G G KG LGP G PGP G++G + GP Sbjct: 615 KGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGP 674 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 G P LPG G GP G PGKEG G +G GP G GP G PGP G++G+ G + Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKG------EPGEPFTKGEKGD 493 K KG D G+KGD+GE G+PG G GP+G KG +PG P GEKG Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794 Query: 494 RGEPGVIG---SQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGI 550 G PG+ G QG KG G PG PG G G +G G +G G RGP G G G G Sbjct: 795 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854 Query: 551 PGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGE 607 GK G KG G G G G GLPGP+G G PG K PG PG DG PG PG RG G Sbjct: 855 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 914 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD 667 +G G G PG +GPQG G TG G G PG GP G GLPGT G G G PG Sbjct: 915 QGKTGPPGPPGVVGPQGAA--GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972 Query: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCGNC----QASVPGLKSNKGEEGGAGEPGKYD 723 G PG GP G L+ F G A PGLK N+G G G G Sbjct: 973 GAPGKDGPAG--------------LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 1018 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 G GP GPPG PG +GP G+ GE+G PG G G G G+ G G PGP GPPG Sbjct: 1019 ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPG 1078 Query: 784 LMGR------TGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYK 830 + G G PG G KG KG GPPG PGP GP G P G + Sbjct: 1079 VAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFG 1138 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG 890 KG + GPPGP G +G PGP GE G G G G PG G RGPAGP G G G Sbjct: 1139 AKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQG 1198 Query: 891 KPGAPG---PPGVPGEPGE------------------RGPVGDIGFPGPEGPSGKPGING 929 PG G PPG GEPGE RG G+ G PG GP G G G Sbjct: 1199 PPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG 1258 Query: 930 KDGIPGAQGIMGKPGDRGPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 DG G G +G PGD GP GE RG G GDRG GE G+PG G G GP GP G Sbjct: 1259 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLG 1318 Query: 987 NKGSMGSPGHQG---------PPGSPGIPGIPADAVSFEEIKKYINQEVLR-----IFEE 1032 +G GSPG +G PG+ G PG K + LR + ++ Sbjct: 1319 KRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-GPDGLRGLPGSVGQQ 1377 Query: 1033 RMAVFLSQLK---------LPAAMLAAQAYGRPGPPGKDGLPGPPGD---------PGPQ 1074 Q LP A A G G PG GL GPPG+ PGPQ Sbjct: 1378 GRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQ 1437 Query: 1075 GYRGQKGERGEPG----IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G GQKGE G PG IG G PGLPG + G G+ GA GP GP G G P Sbjct: 1438 GSPGQKGEMGIPGASGPIGPGGPPGLPGPA--GPKGAKGATGPGGPKGEKGVQGP 1490 Score = 615 bits (1587), Expect = e-176 Identities = 399/983 (40%), Positives = 464/983 (47%), Gaps = 148/983 (15%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P LK + + +G G G G PG+ G +G G +G G PG PG KG++GF+G Sbjct: 504 PGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGL 563 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALP-- 390 G GEKG +G+ G L G GE+G +GD +GP G PG G +G GP GPP +P Sbjct: 564 PGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGP 623 Query: 391 -------------GSLGIQGPQGPPGKE------------------GQRGRRGKTGPPGK 419 GSLG QG GPPG++ G++G +GK G PG Sbjct: 624 PGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGM 683 Query: 420 PGPPGPPGPPGIQGIHQTLG-----------GYYN-KDNKGNDE-HEAGGLKGDKGETGL 466 PG GPPG PG +G T G GY + KG D G KG+KGE G Sbjct: 684 PGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF 743 Query: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS------ 520 PGF G +G KG +GE G P G RGE G G +G G GDPGPPGL+G Sbjct: 744 PGFKGDIGVKGDRGEVGVP------GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGV 797 Query: 521 ---PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----------GI 566 PG G+QG GS+G G PG G G G+ GK G +GE+G G G Sbjct: 798 PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGK 857 Query: 567 IGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 G G G G GPPG + LPG G +G PG GP GP G+ GLPG G G++G QG Sbjct: 858 SGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGK 917 Query: 625 IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684 G PG G GP G G GP G G PG PG PG G+PG GK G G PG P A Sbjct: 918 TGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK 977 Query: 685 LGDIGALLKNFCGN----CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIP 740 G G L+ F G A PGLK N+G G G G G GP GPPG P Sbjct: 978 DGPAG--LRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035 Query: 741 GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL------MGRTGHPGPT 794 G +GP G+ GE+G PG G G G G+ G G PGP GPPG+ G G PG Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095 Query: 795 GAKGEKGSDGPPGKPGPPGPPGIPFNE-------RNGMSSLYKIKGGVNVPSYPGPPGPP 847 G KG KG GPPG PGP GP G P G + KG + GPPGP Sbjct: 1096 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPI 1155 Query: 848 GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGI---------------------A 886 G +G PGP GE G G G G PG G RGPAGP G Sbjct: 1156 GLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEP 1215 Query: 887 GMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDR 946 G SG PG G PGV G GERG G+ G PG GP G G G DG G G +G PGD Sbjct: 1216 GESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDP 1275 Query: 947 GPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSP 1003 GP GE RG G GDRG GE G+PG G G GP GP G +G GSPG +G G Sbjct: 1276 GPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGK 1335 Query: 1004 GIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDG 1063 G G P A+ + + A L + GRPG G+ G Sbjct: 1336 GAKGDPG-AIG-------APGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAG 1387 Query: 1064 LPGPPGDPGPQGYRGQ---KGERGEPGI----------------GLPGSPGLPGTSA-LG 1103 PGP G PG G RG KGE+G PG+ GLPG G PG +G Sbjct: 1388 PPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMG 1447 Query: 1104 LPGSPGAPGPQGPPGPSGRCNPE 1126 +PG+ G GP GPPG G P+ Sbjct: 1448 IPGASGPIGPGGPPGLPGPAGPK 1470 Score = 573 bits (1476), Expect = e-163 Identities = 366/883 (41%), Positives = 422/883 (47%), Gaps = 137/883 (15%) Query: 291 KGEAGLPGAPGSPGQKGH---------KGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 +G+ GLPG PGS G GH KG G +G G G+PG +G +G +G +G G Sbjct: 675 QGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH 734 Query: 342 KGEQGE------KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL------ 389 KGE+GE KGD + G GE G+ G G GP GPKG G TG PGPP L Sbjct: 735 KGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK 794 Query: 390 ------PGSLGIQGPQGP------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQT 437 PG G QGP+G PG G++G RG +G G G GP GP G +G Sbjct: 795 LGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGA 854 Query: 438 LGGYYNKDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G K G D GL G +G G PG G GP G+ G PG P +GE G Sbjct: 855 TGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGF 914 Query: 494 RGE------PGVIGSQGVKGE---------PGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538 +G+ PGV+G QG GE PG PGPPG G PG G++G+ G GP G Sbjct: 915 QGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974 Query: 539 PGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNP 596 PG G G G PG++G+ G G PG G GP G PGP G G G + G G G P Sbjct: 975 PGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAA--GSGGPIGPP 1032 Query: 597 GAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGI---QGPRGLPGLP 652 G PGP+GP G G GV G G IGP G G+ G G GPAG PG+ G +G G P Sbjct: 1033 GRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP 1092 Query: 653 GTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGAL--LKNFCGNCQASVPGLKSNK 710 G GT GN G G G PG GP G P A G+ GA +F G Sbjct: 1093 GQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1152 Query: 711 GEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIP 770 G G G PG GD+GP GPPG PG GP G G G G PG G+ G P Sbjct: 1153 GPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN---LGPP 1209 Query: 771 GIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYK 830 G G PG +G PG+ G G GP G +GEKG G PG+PGPPGP G P + + Sbjct: 1210 GEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG-PTGDDGPKGN--- 1265 Query: 831 IKGGVNVPSYPGPPGPPGP------KGDPGPVGEPGAMGLPGLEGF---PGVKGDRGPAG 881 G V P PGPPG GP KGD G GEPG G PG G PG G RGPAG Sbjct: 1266 -PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1324 Query: 882 PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMG 941 PG G G GA G PG G PG+ GPVG P GP+GKPG +G G+PG+ G G Sbjct: 1325 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPDGLRGLPGSVGQQG 1378 Query: 942 KPG---DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 +PG GP G G G+PG RG G +G+ G G+ G IGP G G KG G PG QG Sbjct: 1379 RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1438 Query: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 PG G GIP A G GP Sbjct: 1439 SPGQKGEMGIPG-----------------------------------------ASGPIGP 1457 Query: 1059 PGKDGLPGPPGDPG------PQGYRGQKGERGEPGIGLPGSPG 1095 G GLPGP G G P G +G+KG +G P G PG PG Sbjct: 1458 GGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPP--GHPGPPG 1498 Score = 561 bits (1447), Expect = e-159 Identities = 367/915 (40%), Positives = 424/915 (46%), Gaps = 122/915 (13%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS--------------K 336 +G AGL G PG G G G+PGE G G G PG G G G+ K Sbjct: 404 EGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDK 463 Query: 337 GET--------------------GEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKG 376 G G G G G P G G GLKG+ G GP GP+G Sbjct: 464 GPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRG 523 Query: 377 EKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQ 436 +G TGPPG G G G +G PG G +G RG G PG PG G G G QG Sbjct: 524 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQG--- 580 Query: 437 TLGGYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDR 494 L G +D + D+ E G GL G+ G GL +GPKG G PG P +G G + Sbjct: 581 -LPGPPGEDGERGDDGEIGPRGLPGESGPRGL------LGPKGPPGIPGPPGVRGMDGPQ 633 Query: 495 GEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG-- 552 G G +G QG G PG G PG G PG +G G G GP+G PG G+PG G PG Sbjct: 634 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP 693 Query: 553 -KQGIKGEKGD--PGGIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPGPRGPK 605 K+G G KG+ P G GP G PGP+G G G K GE G DG PG G G K Sbjct: 694 GKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVK 753 Query: 606 GERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPG 665 G+RG GV GS G+ GP+G GRTG G G PG+ G +G G+PG PG PG G G Sbjct: 754 GDRGEVGVPGSRGEDGPEGP--KGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKG 811 Query: 666 RDGKPGLPGPPGDPIALPLLGDIGALLKN--FCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 G PG PG G+ A L G G + Q G G +G +G G + Sbjct: 812 SLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG 871 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG 783 +G GP+GP G PG +GP G G+ G PG PG++G+ G QG G PG PG GP G Sbjct: 872 PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG 931 Query: 784 LMGRTG------HPGPTGAKGEKGSDGPPGKPGP---PGPPGIPFNERNGMSSLYKIKGG 834 G TG HPGP G GE+G G GK G PGPPG P G ++G Sbjct: 932 AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP-----GKDGPAGLRGF 986 Query: 835 VNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA 894 PG G PG KG+ GP G PG G PG G G GP GPPG G G PGA Sbjct: 987 PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERG---AAGSGGPIGPPGRPGPQGPPGA 1043 Query: 895 PGPPGVPGEPGERGPVGDIGFPGP---EGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGE 951 G GVPGE G GP G G GP GP+G PG+ G+DG G G G+ G +G KGE Sbjct: 1044 AGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1103 Query: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPAD 1011 G G PG G G+ G G G GA GP G G KG G+ G GPPG G+ G+P Sbjct: 1104 HGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGP 1163 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 + E G PGPPG G GP G Sbjct: 1164 SGEKGETGD-----------------------------VGPMGPPGPPGPRGPAGPNGAD 1194 Query: 1072 GPQ------GYRGQKGERGEPG-IGLPGSPGLPGTSA-------LGLPGSPGAPGPQGPP 1117 GPQ G G GE+GEPG G PG G PG G G PG PGP GP Sbjct: 1195 GPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPK 1254 Query: 1118 GPSGRCNPEDCLYPV 1132 GP+G P+ PV Sbjct: 1255 GPTGDDGPKGNPGPV 1269 Score = 523 bits (1347), Expect = e-148 Identities = 363/962 (37%), Positives = 432/962 (44%), Gaps = 176/962 (18%) Query: 272 SSYLPAKQELKDQCQCIPNKG-----EAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQ 326 SS LP +E + Q P E G G G + G++ P Sbjct: 305 SSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPAL 364 Query: 327 KGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP 386 E G+ G +G +GEKG+PA+ L+ + GPPGP+G G GPPG Sbjct: 365 SAETAHSGAAAH-GPRGLKGEKGEPAV--------LEPGMLVEGPPGPEGPAGLIGPPG- 414 Query: 387 PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDN 446 IQG GP G G+RG G+ G PG G PGPPG + GG Sbjct: 415 --------IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPV 466 Query: 447 KGNDEHEAGGL--KGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 E +A + + G PG G G G G+PG P KGE GD G G G QG Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 505 VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGE---------HGIPGKQG 555 + G PG G G G+ G +G G G G RG G GLPGE G+PG G Sbjct: 527 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586 Query: 556 IKGEKGDPGGIIGPPGLP---GPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 GE+GD G IGP GLP GP+G GP G PG PG G G GP+GPKG G G Sbjct: 587 EDGERGDDGE-IGPRGLPGESGPRGLLGPKGP--PGIPGPPGVRGMDGPQGPKGSLGPQG 643 Query: 613 VHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDG 668 G PG G G G+PG GA GP GE G QG GLPG+PG+ PG PG +G PG G Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 703 Query: 669 KPGLPGPPGDPIALP----------------------------LLGDIGALLKNFCGNCQ 700 G GP G P+ P GDIG +K G + Sbjct: 704 NQGPSGPQG-PLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIG--VKGDRG--E 758 Query: 701 ASVPGLKSN------KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGY 754 VPG + KG G G+PG M KG +G G PG PGR+GPKGS G G+ Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818 Query: 755 PGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGP--------- 805 PG GEKG GL G G G GPTGP G G G G +GAKG G DGP Sbjct: 819 PGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL 878 Query: 806 ---------PGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPP--------- 847 PG GPPGPPG ++G+ +G V GPPGPP Sbjct: 879 PGPQGPNGFPGPKGPPGPPG-----KDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 933 Query: 848 ------GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 G +G PGP G PG GLPG G G KGD GP G PG G +G G PG G+P Sbjct: 934 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 993 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 G G G G+ G GP GP+G PG G G G G G+PG +GP G G++G+PG++ Sbjct: 994 GTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 1053 Query: 962 GSQGERGKPGLTGMKGAIGPMGPP------GNKGSMGSPGHQGPPGSPGIPGIPADAVSF 1015 G G G+ G+ G G GP GPP G+KG +G PG +G G+ G G P Sbjct: 1054 GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGP---- 1109 Query: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQG 1075 P + G G PG G G PG GPQG Sbjct: 1110 ----------------------------PGPI------GPVGQPGAAGADGEPGARGPQG 1135 Query: 1076 YRGQKGERGEPG-------IGLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSGRCN 1124 + G KG+ G G IGL G PG G T +G G PG PGP+GP GP+G Sbjct: 1136 HFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1195 Query: 1125 PE 1126 P+ Sbjct: 1196 PQ 1197 Score = 312 bits (800), Expect = 1e-84 Identities = 217/577 (37%), Positives = 259/577 (44%), Gaps = 109/577 (18%) Query: 583 GKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGI 642 G +L E G A GPRG KGE+G P V PG + G PG G G G PGI Sbjct: 361 GPALSAETAHSG-AAAHGPRGLKGEKGEPAVL-EPGMLVE---GPPGPEGPAGLIGPPGI 415 Query: 643 QGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702 QG G G PG G PG G+PG DG PG PPG + LP G Sbjct: 416 QGNPGPVGDPGERGPPGRAGLPGSDGAPG---PPGTSLMLPFRFGSGG------------ 460 Query: 703 VPGLKSNKGEEGG--AGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGE 760 G++G A + + ++ ++ + RGPPG G G G G+ G PG+ GE Sbjct: 461 --------GDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGE 512 Query: 761 KGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFN 820 GD G QG G G TGPPG GR G G GA+G G G G G G PG+P Sbjct: 513 SGDLGPQGPRGPQGL---TGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 569 Query: 821 ERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG------EPGAMGL------PGLE 868 + + +G PGPPG G +GD G +G E G GL PG+ Sbjct: 570 KGH--------RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP 621 Query: 869 GFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI- 927 G PGV+G GP GP G G G+PG PG G PG G GP G IG G +GP GKPG+ Sbjct: 622 GPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLP 681 Query: 928 -----NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPM 982 +G G PG +G G G++GP G +G G PG RG +G G GL G KG G Sbjct: 682 GMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGED 741 Query: 983 GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK 1042 G PG KG +G G +G G PG Sbjct: 742 GFPGFKGDIGVKGDRGEVGVPG-------------------------------------- 763 Query: 1043 LPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTS-A 1101 + G GP G G GP GDPGP G G+KG+ G PG LPG PG G + Sbjct: 764 ---------SRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG--LPGYPGRQGPKGS 812 Query: 1102 LGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQR 1138 LG PG PGA G +G G SG+ P P QR Sbjct: 813 LGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 849 Score = 287 bits (735), Expect = 3e-77 Identities = 173/387 (44%), Positives = 206/387 (53%), Gaps = 36/387 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KGE G G G PG G +G G NG G G PG G G G KGE GE G G +G+ Sbjct: 1167 KGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGE 1226 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 P + G GE G KG+ G G PGP G KG TG GP PG +G G GPPG+ G RG+ Sbjct: 1227 PGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQ 1286 Query: 411 ------RGKTGPPGKPGPPGP---PGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-GLKGD 460 RG+ G PG+PG PGP GPPG G G + G++ + G G KGD Sbjct: 1287 DGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG------SPGSEGRQGGKGAKGD 1340 Query: 461 KGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS 520 G G PG G VGP G G+P G G RG PG +G QG G G GPPG +G Sbjct: 1341 PGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGP 1394 Query: 521 PGLKGQQGSAGSMGPRGPPGDVGL---PGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGP 575 PGL G +G AG+ G +G PG +GL PGE G G +G+ G +G PG G +G PG GP Sbjct: 1395 PGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGP 1454 Query: 576 KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIG----PQGIGIPGRT 631 G GPPG LPG G G GA GP GPKGE+G+ G G PG G P I +P +T Sbjct: 1455 IGPGGPPG--LPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKT 1512 Query: 632 GAQGPAGEPGIQGPRGLP--GLPGTPG 656 + G +Q +P G PG+PG Sbjct: 1513 -RRSVDGSRLMQEDEAIPTGGAPGSPG 1538 Score = 203 bits (516), Expect = 9e-52 Identities = 138/333 (41%), Positives = 157/333 (47%), Gaps = 59/333 (17%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 N G G PG PG PG+ G +G+ G G G G PGQ G G G G G G++G G Sbjct: 1265 NPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAG 1324 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 P G G G KGD G G PG G G GP G P G G +G PG GQ+G Sbjct: 1325 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP------GPDGLRGLPGSVGQQG 1378 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 R G TG G PGP GPPG PG++G +AG KGE G PG Sbjct: 1379 RPGATGQAGPPGPVGPPGLPGLRG-------------------DAGA----KGEKGHPGL 1415 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529 G +GP G+ +GEKGDRG PG GS G KGE G PG G IG PG G Sbjct: 1416 IGLIGPPGE---------QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIG-PG-----GP 1460 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G GP GP G G G PG G KGEK G+ GPPG PGP GE P LP + Sbjct: 1461 PGLPGPAGPKGAKGATG----PG--GPKGEK----GVQGPPGHPGPPGEVIQP---LPIQ 1507 Query: 590 PGLDGNPGAPGPRGPKGERGLP--GVHGSPGDI 620 G R + + +P G GSPG + Sbjct: 1508 MPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGL 1540 Score = 144 bits (364), Expect = 4e-34 Identities = 102/282 (36%), Positives = 125/282 (44%), Gaps = 61/282 (21%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 ++GE G PG PGSPG G G PG G G G PG +G QG +G+KG+ G G G+ G Sbjct: 1292 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351 Query: 350 DPALAGLNGE------NGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG------------ 391 AG G+ GL G +G G PG G+ G GP GPP LPG Sbjct: 1352 PVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKG 1411 Query: 392 ------------------SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G+ GPQG PG++G+ G G +GP G GPPG PGP G +G Sbjct: 1412 HPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKG 1471 Query: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 G GG KG+KG G PG P GP G+ +P P +K Sbjct: 1472 AKGATG--------------PGGPKGEKGVQGPPGHP---GPPGEVIQP-LPIQMPKKTR 1513 Query: 494 RGEPGVIGSQGVKGEP--GDPGPPGLIGSPGLKGQQGSAGSM 533 R G Q + P G PG PG GL+ GS S+ Sbjct: 1514 RSVDGSRLMQEDEAIPTGGAPGSPG-----GLEEIFGSLDSL 1550 Score = 109 bits (272), Expect = 2e-23 Identities = 65/153 (42%), Positives = 78/153 (50%), Gaps = 16/153 (10%) Query: 276 PAKQELKDQCQCIPNK-GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG 334 PA + D + +P G+ G PGA G G G G PG GL G G G+KG G G Sbjct: 1358 PAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIG 1417 Query: 335 ---SKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG 391 GE GEKG++G L G G G KG++G G GP GP GPP LPG Sbjct: 1418 LIGPPGEQGEKGDRG------LPGPQGSPGQKGEMGIPGASGP------IGPGGPPGLPG 1465 Query: 392 SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPG 424 G +G +G G G +G +G GPPG PGPPG Sbjct: 1466 PAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPG 1498 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 622 bits (1603), Expect = e-178 Identities = 399/965 (41%), Positives = 466/965 (48%), Gaps = 171/965 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG KGH+GE G G G PG G +GE G G +G GE Sbjct: 609 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 668 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP---PGP------------ 386 +G G G P +AG++G G KG++GP G PGP G++G+ GP PGP Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728 Query: 387 ---PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 P L G G GP G PGKEGQ G +G GPPG GP G PGP G++G G + Sbjct: 729 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 788 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 K KG D GLKGD+GE G G G GP+G KG G G G GE G Sbjct: 789 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 848 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGL------KGQQGSAGSMGPRG------PPGDVGLPGE 547 +G G+ G PG GP G G PG KG +G AG GPRG P G G G Sbjct: 849 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908 Query: 548 HGIPGKQGIKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKS-LPGEPG------L 592 G PG +G G G PG G GP G PGPKG GPPGK LPG PG Sbjct: 909 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 968 Query: 593 DGNPGAPGP------RGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQG- 644 G G PGP +GP GE G G G PG GP G G+PG G +G G+PG QG Sbjct: 969 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028 Query: 645 -----PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNC 699 P GL G PG G PG G PG G G GPPG P+ P G+ G+ G Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG-PVGSP--GERGS-----AGTA 1080 Query: 700 -QASVPGLKSNKGEEGGAGE---PGKYDSMARKGDIGPRGPPGIPGREGPKGS------K 749 +PG +G G AGE PG+ G G +GP G+PG GP GS K Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140 Query: 750 GERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG---EKGSDGPP 806 GE G PG G KGD+G G PG PG GP G PG+ G G PGP G +G +KG +G Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200 Query: 807 GKPGPPGPPGI-----PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA 861 G PGPPGP G+ P E+ + G + P PGP GP GP G GP G PG+ Sbjct: 1201 GFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQGPPGS 1256 Query: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGM------------SGKPGAPGPPGVPGEPGERGP 909 +G G G G G+ G GPPG AG+ +G PGA GPPG G PG+ GP Sbjct: 1257 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316 Query: 910 VGD---IGFPGPEGPSGKPGINGKDGI---PGAQGIMGKPGDRGPKGERGDQGIPGDRG- 962 G+ +GFPG GP G+PG G+DG+ G G G+PG GP GE G G PG RG Sbjct: 1317 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1376 Query: 963 --SQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 + G G+ G G KG G GPPG G +G G G PG G+ GIP Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP--------- 1427 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP--------- 1071 + + LP A A G PGP G GLPG GDP Sbjct: 1428 -----------------VGEQGLPGA---AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1467 Query: 1072 ------GPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGPS 1120 GP G +G+KG+RG PG G G G+PG + LG PG PG PGPQGP G Sbjct: 1468 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1527 Query: 1121 GRCNP 1125 G P Sbjct: 1528 GSTGP 1532 Score = 587 bits (1514), Expect = e-167 Identities = 373/903 (41%), Positives = 447/903 (49%), Gaps = 100/903 (11%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G+ G PG G+ G +G PG +G G PG PG KG++GF+G G G+KG +GE+G Sbjct: 573 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 632 Query: 351 PALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 G G++G++G+ +GP G PG G +G GP G P PG G+ G GPPG +G Sbjct: 633 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 692 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G +G+ GPPG+ G PGP G PG QG +G K +G GL G G G P Sbjct: 693 MGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGKP-----GLAGLPGADGPP 744 Query: 468 GFPGSVGPKGQKGEPGEPFTKGE------KGDRGEPGVIGSQGVKGEPGDPGPPGLIGSP 521 G PG G G+KG G P +G +G +G GV G +G KGE G+ G PG G Sbjct: 745 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 804 Query: 522 GLKGQQGSAGSMGPRG---PPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPK 576 GLKG +G G +GPRG P G G G G PG G GEKG G G+ G PG GPK Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 577 GEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI------- 625 G G PG G G+ G PG G RGP G RG G G G GP+G Sbjct: 865 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 924 Query: 626 GIPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPGLPGPPGDPIAL 682 G PG G QGP G G GP+G PG PG PG PG G G GK G PGP G Sbjct: 925 GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 984 Query: 683 PLLGDIGALLKNFCGNCQASVP----GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G+ G + + G+ P GL G+EG G+PG + G G RG PG Sbjct: 985 GPTGETGPIGER--GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 1042 Query: 739 ---IPGREGP---KGSKGERGYPG---IPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTG 789 +PG +G KG +G +G PG PGE+G G G G+PG PGP GPPG G G Sbjct: 1043 ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1102 Query: 790 HPGPTGAKGEKGSDG---PPGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPG 842 PG G +G G DG P G PGP GP G P + + G KG PG Sbjct: 1103 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1162 Query: 843 PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPG 902 PPG GP G PG G G G G +G G KGD G G PG G G G PGPPG G Sbjct: 1163 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1222 Query: 903 EPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR- 961 E G+ GP+G G PGP GP G G +G G PG+ G +G G++G GE G+ G PG+ Sbjct: 1223 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282 Query: 962 --GSQGERGKPGLTGMKGAIGP---MGPPGNKGSMGSPGHQGPPGSPGIPGIPA----DA 1012 G +GERG+ G G GA GP GPPG+ G G+PG G PG PG PG P D Sbjct: 1283 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1342 Query: 1013 VSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG 1072 V ++ + P + G PGPPGK G PG G G Sbjct: 1343 VGGDKGED------------------GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1384 Query: 1073 PQGYRGQKGERGEPG-------IGLPGSPGLPGTSAL-GLPGS------PGAPGPQGPPG 1118 QG +G KGE G G +G G G PG L G+PG PGA G GPPG Sbjct: 1385 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1444 Query: 1119 PSG 1121 P G Sbjct: 1445 PMG 1447 Score = 565 bits (1457), Expect = e-161 Identities = 363/908 (39%), Positives = 431/908 (47%), Gaps = 170/908 (18%) Query: 301 GSPGQKGHKGEPG--ENGL--HGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGL 356 G+ G+KG KGEP E G+ G PG G G G G +G TG G+ G++G P GL Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 491 Query: 357 NGENGLKGDLGP------------------------------------HGPPGPKGEKGD 380 G +GL G G GPPGP G Sbjct: 492 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL--- 548 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGG 440 TG PGP PGS G +G G PG +G RG +G GP GKPG G PG G +G+ G Sbjct: 549 TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 608 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVI 500 KGD+G GLPG PG G +G++G G P G+ G RGE G I Sbjct: 609 -----------------KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 651 Query: 501 GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEK 560 G +G+ GE G G G G+PG GQ G AG GP GP G++G GE G PG+QG Sbjct: 652 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG----- 706 Query: 561 GDPGGIIGPPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619 +PG P GLPGP+G GPPG+ P G+PGL G PGA GP G G+ G G G+ G Sbjct: 707 -NPG----PQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 761 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGD 678 GPQG IG PG G +G G G++G +G G G PG G+ G+ G G+ G GP G+ Sbjct: 762 PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 821 Query: 679 PIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G + KG G G+PG KG +G G PG Sbjct: 822 D-------------------------GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 856 Query: 739 IPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG 798 PGR+GPKGS G G+PG GEKG G+ G PG G GPTGP G G G G G KG Sbjct: 857 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 799 EKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGE 858 G DGPPG PG GP G +G V P GPPGPPG G PG G+ Sbjct: 917 TSGGDGPPGPPGERGPQGP--------------QGPVGFPGPKGPPGPPGKDGLPGHPGQ 962 Query: 859 PGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE---PGERGPVGDIGF 915 G G G G PG G GP GP G G G+ G PGPPG PGE PG G G G Sbjct: 963 RGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 1022 Query: 916 PGPEGPSGKPG------INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGK 969 PGP+G SGK G G+ G+PGAQG G G GP+G G G PG+RGS G G Sbjct: 1023 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1082 Query: 970 PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGI--------PGIPADAVSFEEIKKY 1021 GL G G GP GP G KG+ G G QGP G G+ P PA + + K Sbjct: 1083 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1142 Query: 1022 INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP---------PGDPG 1072 I + P + G GPPG GL GP G+PG Sbjct: 1143 IGE-------------------PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183 Query: 1073 PQGYRGQKGERGEPG----------IGLPGSPGLPGTSA----LGLPGSPGAPGPQGPPG 1118 P+G +G G++G+ G IGL G PG PG +G G PG PGP+GP G Sbjct: 1184 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1243 Query: 1119 PSGRCNPE 1126 P+G P+ Sbjct: 1244 PNGADGPQ 1251 Score = 531 bits (1369), Expect = e-150 Identities = 345/840 (41%), Positives = 401/840 (47%), Gaps = 144/840 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPG------FPGQKGEQGFEGSKGETGEKGEQ 345 G AGLPGA G PG G +G+ GE G G PG +PG +G +G +G +G G KGE+ Sbjct: 733 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 792 Query: 346 GEKGDPALAG---LNGENGLKGDLGPHG---PPGPKGEKGDTGPPGP------------P 387 GE G P G L G+ G G +GP G P GPKG G TG PGP P Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 852 Query: 388 ALPGSLGIQGPQGP---------------------PGKEGQRG------RRGKTGPPGKP 420 LPG G QGP+G PG GQRG RG GP GKP Sbjct: 853 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 912 Query: 421 GP---------------------------PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 GP PGP GPPG G KD + Sbjct: 913 GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG----------KDGLPGHPGQ 962 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEP------GEPFTKGEKGDRGEPGVIGSQGVKG 507 G G +G+TG PG G VGP+G GE G P G G++G PG G +G KG Sbjct: 963 RGE-TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 1021 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 +PG G G G GL+G G G G +G PG G G G PG G GE+G G G Sbjct: 1022 DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1081 Query: 566 IIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG 624 IG PG PGP+G GP G K PGE G G G G +GP G G G GSPG+ G +G Sbjct: 1082 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1141 Query: 625 -IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALP 683 IG PG+ G++G GE G GP GL G G PG G DG PG G+ G+ G GD A Sbjct: 1142 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1201 Query: 684 LLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA------GEPGKYDSMARKGDIGPRGPP 737 G G + +PG KGE G G PG G GP+GPP Sbjct: 1202 FPGPPGPI-------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1254 Query: 738 GIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAK 797 G G G G KGE G G PG G+ G+ G G G G GPPG G G GP G Sbjct: 1255 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1314 Query: 798 GEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG 857 G KG+ GP G PG PGPPG P G + KG P PGPPGP G G PGP G Sbjct: 1315 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1372 Query: 858 E---PGAMGLPGLEGFPGVKGDRGPAGPPGIA------GMSGKPGAPGPPGVPGEPGERG 908 + PGA G G +G G KG+ G GPPG G +GKPG G G+PG GE+G Sbjct: 1373 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1432 Query: 909 PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKP------GDRGPKGERGDQGIPGDRG 962 G G GP GP G PG+ G G PG++G G P G G +GE+GD+G+PG +G Sbjct: 1433 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1492 Query: 963 SQGERGKPGLTGMKGAIGPMGPP---------GNKGSMGSPGHQ------GPPGSPGIPG 1007 S G +G G+ G G +GP GPP GNKGS G G + GPPGSPG PG Sbjct: 1493 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552 Score = 419 bits (1078), Expect = e-117 Identities = 257/601 (42%), Positives = 303/601 (50%), Gaps = 59/601 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G G G G G G PGE GL GA G G KG+ G +G G+ G G +G G+ Sbjct: 984 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1043 Query: 351 PALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 L G G GLKG GP GPPGP GE+G G GP LPG G QGP GP G++G Sbjct: 1044 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1103 Query: 408 RGRRGKTGPPGK---------PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--- 455 G +G GP G+ PGP GP G PG G +G K +KG D+ E G Sbjct: 1104 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG-DKGENGPPG 1162 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KG 507 GL+G G G+ G G GP+GQ+G G+ +G +G G PG IG QG+ KG Sbjct: 1163 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1222 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 E GD GP G G PG +G QG G+ GP+GPPG VG G G G+ G G G PG G Sbjct: 1223 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1282 Query: 566 IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 + GP G G KGEAGPPG + G PG G PG GP+G G G PG G PG+ GP G Sbjct: 1283 VGGPKGERGEKGEAGPPGAA--GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1340 Query: 625 ---------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 G PG+ G GP+GE G GP G G PG G G G G G+ G GP Sbjct: 1341 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1400 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 PG G +G A PG + +G G GE G + + G GP G Sbjct: 1401 PGK------TGPVGP-------QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1447 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 PPG+PG +G GSKGE+G+PG+ G G G QG G G PG G PG G G PGP Sbjct: 1448 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA- 1506 Query: 796 AKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGP 855 G G GPPG PGP GP G G + KG +P PG PGPPG P P Sbjct: 1507 --GPLGPPGPPGLPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559 Query: 856 V 856 + Sbjct: 1560 I 1560 Score = 413 bits (1061), Expect = e-115 Identities = 293/768 (38%), Positives = 356/768 (46%), Gaps = 135/768 (17%) Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPG----SVGPKGQKGEPGEPFTKGEKGDRGE 496 Y NK+ G D + GD GE + P ++ PG P + D E Sbjct: 372 YENKEIDGRDSDLL--VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP----AETDITE 425 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G GE G G P ++ PG+ + GPPG G G G PG QG Sbjct: 426 TSING-HGAYGEKGQKGEPAVV-EPGMLVE----------GPPGPAGPAGIMGPPGLQGP 473 Query: 557 KGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGE------- 607 G GDPG G G PGLPG G GPPG L P G G+ GP E Sbjct: 474 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLM-LPFRYGGDGSKGPTISAQEAQAQAIL 532 Query: 608 -------RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G G GP +G PG +GA+G +G+PG QGPRG+ G PG G PG Sbjct: 533 QQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 590 Query: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 G PG DG G+PG PG GD G F G +PG K ++GE G G PG Sbjct: 591 RGRPGADGGRGMPGEPGAK------GDRG-----FDG--LPGLPGDKGHRGERGPQGPPG 637 Query: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 +G+ G GP G+PG GP+G G RG PG PG+ G G+ G PG G GP G Sbjct: 638 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 697 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY 840 PG G+ G+PGP G G +G GPPG+ GP G PG L + G P + Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG-----------LAGLPGADGPPGH 746 Query: 841 PG------------PPGPPGPKGDPGPVGEPGAMGLPGL---------EGFPGVKGD--- 876 PG PPGP GP G PGP G GA G+ GL +GFPG KGD Sbjct: 747 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 806 Query: 877 ------------RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGK 924 RG GP G G +G G PGP G GE G+ G G G+PG +GP G Sbjct: 807 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 866 Query: 925 ---PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 PG G +G GA+G+ GKPG P+G+RG G G RG++G GKPG G G GP Sbjct: 867 TGFPGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 923 Query: 982 MGPPGNKGSMGS------PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 GPPG +G G PG +GPPG PG G+P + Q F+ + Sbjct: 924 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG----------HPGQRGETGFQGKTG 973 Query: 1036 VFLSQLKLPAAMLAAQA-YGRPGPPGKDGLPGPPGDPGPQGY---RGQKGERGEPGI-GL 1090 P ++ Q G GP G+ G PGPPG PG QG G++G +G+PG G+ Sbjct: 974 P-----PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1028 Query: 1091 PGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQR 1138 G G G G PG G PG QG PG G P+ PV +R Sbjct: 1029 SGKDGPAGLR--GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1074 Score = 328 bits (842), Expect = 1e-89 Identities = 196/434 (45%), Positives = 229/434 (52%), Gaps = 49/434 (11%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHG---APGFPGQKGEQGFEGSKGETGEKGEQG 346 +KGE G PG GS G KG G PG GL G APG G GE G G +G G+KG++G Sbjct: 1139 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1198 Query: 347 EKGDPA---------LAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPG 391 +G P L G GE G GD+GP GPPGP G +G GP GPP G Sbjct: 1199 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG 1258 Query: 392 SLGIQGPQGPPGK---------------EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQ 436 S+G G +G PG+ +G+RG +G+ GPPG GPPG GPPG G Sbjct: 1259 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1318 Query: 437 TLG--GYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 G G+ + AG G+ GDKGE G PG PG GP G+ G PG P +G G Sbjct: 1319 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1378 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 G G G +G KGE G GPPG G G +G G G G RG PG V GE G+PG Sbjct: 1379 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPG 1435 Query: 553 KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 G G P G +GPPGLPG KG+ G G+ G PGL G G PG +G KG+RGLPG Sbjct: 1436 AAGQDG----PPGPMGPPGLPGLKGDPGSKGEK--GHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 GSPG G GIPG G GP G PG+ GP+G G G+ G G G G G PG Sbjct: 1490 TQGSPGAKGDG--GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1547 Query: 673 PGPPGDPI-ALPLL 685 PGPPG+ I LP+L Sbjct: 1548 PGPPGEVIQPLPIL 1561 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 622 bits (1603), Expect = e-178 Identities = 399/965 (41%), Positives = 466/965 (48%), Gaps = 171/965 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG KGH+GE G G G PG G +GE G G +G GE Sbjct: 558 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 617 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP---PGP------------ 386 +G G G P +AG++G G KG++GP G PGP G++G+ GP PGP Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677 Query: 387 ---PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 P L G G GP G PGKEGQ G +G GPPG GP G PGP G++G G + Sbjct: 678 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 737 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 K KG D GLKGD+GE G G G GP+G KG G G G GE G Sbjct: 738 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 797 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGL------KGQQGSAGSMGPRG------PPGDVGLPGE 547 +G G+ G PG GP G G PG KG +G AG GPRG P G G G Sbjct: 798 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857 Query: 548 HGIPGKQGIKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKS-LPGEPG------L 592 G PG +G G G PG G GP G PGPKG GPPGK LPG PG Sbjct: 858 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917 Query: 593 DGNPGAPGP------RGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQG- 644 G G PGP +GP GE G G G PG GP G G+PG G +G G+PG QG Sbjct: 918 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977 Query: 645 -----PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNC 699 P GL G PG G PG G PG G G GPPG P+ P G+ G+ G Sbjct: 978 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG-PVGSP--GERGS-----AGTA 1029 Query: 700 -QASVPGLKSNKGEEGGAGE---PGKYDSMARKGDIGPRGPPGIPGREGPKGS------K 749 +PG +G G AGE PG+ G G +GP G+PG GP GS K Sbjct: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089 Query: 750 GERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG---EKGSDGPP 806 GE G PG G KGD+G G PG PG GP G PG+ G G PGP G +G +KG +G Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149 Query: 807 GKPGPPGPPGI-----PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA 861 G PGPPGP G+ P E+ + G + P PGP GP GP G GP G PG+ Sbjct: 1150 GFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQGPPGS 1205 Query: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGM------------SGKPGAPGPPGVPGEPGERGP 909 +G G G G G+ G GPPG AG+ +G PGA GPPG G PG+ GP Sbjct: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265 Query: 910 VGD---IGFPGPEGPSGKPGINGKDGI---PGAQGIMGKPGDRGPKGERGDQGIPGDRG- 962 G+ +GFPG GP G+PG G+DG+ G G G+PG GP GE G G PG RG Sbjct: 1266 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1325 Query: 963 --SQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 + G G+ G G KG G GPPG G +G G G PG G+ GIP Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP--------- 1376 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP--------- 1071 + + LP A A G PGP G GLPG GDP Sbjct: 1377 -----------------VGEQGLPGA---AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1416 Query: 1072 ------GPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGPS 1120 GP G +G+KG+RG PG G G G+PG + LG PG PG PGPQGP G Sbjct: 1417 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1476 Query: 1121 GRCNP 1125 G P Sbjct: 1477 GSTGP 1481 Score = 587 bits (1514), Expect = e-167 Identities = 373/903 (41%), Positives = 447/903 (49%), Gaps = 100/903 (11%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G+ G PG G+ G +G PG +G G PG PG KG++GF+G G G+KG +GE+G Sbjct: 522 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581 Query: 351 PALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 G G++G++G+ +GP G PG G +G GP G P PG G+ G GPPG +G Sbjct: 582 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 641 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G +G+ GPPG+ G PGP G PG QG +G K +G GL G G G P Sbjct: 642 MGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGKP-----GLAGLPGADGPP 693 Query: 468 GFPGSVGPKGQKGEPGEPFTKGE------KGDRGEPGVIGSQGVKGEPGDPGPPGLIGSP 521 G PG G G+KG G P +G +G +G GV G +G KGE G+ G PG G Sbjct: 694 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 753 Query: 522 GLKGQQGSAGSMGPRG---PPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPK 576 GLKG +G G +GPRG P G G G G PG G GEKG G G+ G PG GPK Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 577 GEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI------- 625 G G PG G G+ G PG G RGP G RG G G G GP+G Sbjct: 814 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 873 Query: 626 GIPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPGLPGPPGDPIAL 682 G PG G QGP G G GP+G PG PG PG PG G G GK G PGP G Sbjct: 874 GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933 Query: 683 PLLGDIGALLKNFCGNCQASVP----GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G+ G + + G+ P GL G+EG G+PG + G G RG PG Sbjct: 934 GPTGETGPIGER--GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 991 Query: 739 ---IPGREGP---KGSKGERGYPG---IPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTG 789 +PG +G KG +G +G PG PGE+G G G G+PG PGP GPPG G G Sbjct: 992 ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1051 Query: 790 HPGPTGAKGEKGSDG---PPGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPG 842 PG G +G G DG P G PGP GP G P + + G KG PG Sbjct: 1052 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1111 Query: 843 PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPG 902 PPG GP G PG G G G G +G G KGD G G PG G G G PGPPG G Sbjct: 1112 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1171 Query: 903 EPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR- 961 E G+ GP+G G PGP GP G G +G G PG+ G +G G++G GE G+ G PG+ Sbjct: 1172 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231 Query: 962 --GSQGERGKPGLTGMKGAIGP---MGPPGNKGSMGSPGHQGPPGSPGIPGIPA----DA 1012 G +GERG+ G G GA GP GPPG+ G G+PG G PG PG PG P D Sbjct: 1232 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1291 Query: 1013 VSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG 1072 V ++ + P + G PGPPGK G PG G G Sbjct: 1292 VGGDKGED------------------GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1333 Query: 1073 PQGYRGQKGERGEPG-------IGLPGSPGLPGTSAL-GLPGS------PGAPGPQGPPG 1118 QG +G KGE G G +G G G PG L G+PG PGA G GPPG Sbjct: 1334 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1393 Query: 1119 PSG 1121 P G Sbjct: 1394 PMG 1396 Score = 572 bits (1474), Expect = e-163 Identities = 440/1248 (35%), Positives = 559/1248 (44%), Gaps = 177/1248 (14%) Query: 6 PW------KLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDL 59 PW K WLW A T + + + P+ ++ L + N G Sbjct: 3 PWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKA--LDFHN----SPEGISK 56 Query: 60 GDSFSLRRAFCESDKTCFKLGS-ALLIRDTIKIFPKG-LPEEYSVAAMFRVRRNAKKERW 117 F R + T +++ A L T ++FP G PE++S+ + ++ + Sbjct: 57 TTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS--- 113 Query: 118 FLWQVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGIS 177 FL + N+ I QI + V G+ V F+F+ G + + D +WH++ IS Sbjct: 114 FLLSIYNEHGIQQIGVEV--GRSPV-FLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAIS 170 Query: 178 IQSQVISLYMDCNLIARRQTD--EKDTVDFHGRTVIATRASDGKPVDIELHQLKIYCSAN 235 ++ + +++ +DC + D E+ VD +G TV TR D + + ++ Q I Sbjct: 171 VEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLITGDPK 230 Query: 236 LIAQETC------CEISDTKCPE----QDGFGNIASSWVTAHASKMSSY-LPAKQELKDQ 284 A + C C+ S K + Q NI + + M SY A + + Sbjct: 231 -AAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEAPRHVSGT 289 Query: 285 CQCIPNK---GEAGLPGAPGSPGQKGHKGEPGEN----GLHGAPGFPGQKGEQGF----E 333 + P + E L G +K + EN G G GE F E Sbjct: 290 NEPNPVEEIFTEEYLTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEYDFYEYKE 349 Query: 334 GSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGE----------KGDTGP 383 T E+ G PA + E + G G +G G KGE +G GP Sbjct: 350 YEDKPTSPPNEEFGPGVPAETDIT-ETSINGH-GAYGEKGQKGEPAVVEPGMLVEGPPGP 407 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 GP + G G+QGP GPPG G R GPPG+PG PG G PG G L Y Sbjct: 408 AGPAGIMGPPGLQGPTGPPGDPGDR------GPPGRPGLPGADGLPGPPGTMLMLPFRYG 461 Query: 444 KDNKGNDEHEAG-------------GLKGDKGETGLPGFPGSV---------------GP 475 D A L+G G GL G PG V GP Sbjct: 462 GDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGP 521 Query: 476 KGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGP 535 +G +G G P G+ G RG PG G +G+ GEPG G G G PGL G +G G GP Sbjct: 522 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581 Query: 536 RGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGN 595 +GPPG PG+ G+ G+ G G +G PG GP GL GP+G G PG+ PG G+DG Sbjct: 582 QGPPGP---PGDDGMRGEDGEIGPRGLPGE-AGPRGLLGPRGTPGAPGQ--PGMAGVDGP 635 Query: 596 PGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTP 655 PG G GP+GE G PG G+P GPQ G+PG G GP GE G QG GL GLPG Sbjct: 636 PGPKGNMGPQGEPGPPGQQGNP---GPQ--GLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690 Query: 656 GTPGNDGVPGRDGKPGLPGPPG--DPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEE 713 G PG+ G G+ G+ G GPPG PI P G G +K G V GLK +KGE+ Sbjct: 691 GPPGHPGKEGQSGEKGALGPPGPQGPIGYP--GPRG--VKGADG-----VRGLKGSKGEK 741 Query: 714 GGAGEPGKYDSMARKGD---IGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIP 770 G G PG M KGD +G GP G G EGPKG G G PG G+ G++G G+P Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801 Query: 771 GIPGAPGPTGPPGLMGRTGHP---------------------GPTGAKGEKGSDGPPGKP 809 G+PG PG GP G G G P GPTG +G +G+ GP GKP Sbjct: 802 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861 Query: 810 GP------PGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMG 863 GP GPPG P ER +G V P GPPGPPG G PG G+ G G Sbjct: 862 GPKGTSGGDGPPGPP-GERGPQGP----QGPVGFPGPKGPPGPPGKDGLPGHPGQRGETG 916 Query: 864 LPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE---PGERGPVGDIGFPGPEG 920 G G PG G GP GP G G G+ G PGPPG PGE PG G G G PGP+G Sbjct: 917 FQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 976 Query: 921 PSGKP------GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTG 974 SGK G G+ G+PGAQG G G GP+G G G PG+RGS G G GL G Sbjct: 977 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1036 Query: 975 MKGAIGPMGPPGNKGSMGSPGHQGPPGSPGI--------PGIPADAVSFEEIKKYINQEV 1026 G GP GP G KG+ G G QGP G G+ P PA + + K I + Sbjct: 1037 RPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEP- 1095 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEP 1086 ++ + P G PG G DG PGP G G G +G +G RG P Sbjct: 1096 ---GQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1152 Query: 1087 G----IGLPGSPGLPGTSA----LGLPGSPGAPGPQGPPGPSGRCNPE 1126 G IGL G PG PG +G G PG PGP+GP GP+G P+ Sbjct: 1153 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQ 1200 Score = 531 bits (1369), Expect = e-150 Identities = 345/840 (41%), Positives = 401/840 (47%), Gaps = 144/840 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPG------FPGQKGEQGFEGSKGETGEKGEQ 345 G AGLPGA G PG G +G+ GE G G PG +PG +G +G +G +G G KGE+ Sbjct: 682 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741 Query: 346 GEKGDPALAG---LNGENGLKGDLGPHG---PPGPKGEKGDTGPPGP------------P 387 GE G P G L G+ G G +GP G P GPKG G TG PGP P Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 801 Query: 388 ALPGSLGIQGPQGP---------------------PGKEGQRG------RRGKTGPPGKP 420 LPG G QGP+G PG GQRG RG GP GKP Sbjct: 802 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 861 Query: 421 GP---------------------------PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 GP PGP GPPG G KD + Sbjct: 862 GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG----------KDGLPGHPGQ 911 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEP------GEPFTKGEKGDRGEPGVIGSQGVKG 507 G G +G+TG PG G VGP+G GE G P G G++G PG G +G KG Sbjct: 912 RGE-TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 970 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 +PG G G G GL+G G G G +G PG G G G PG G GE+G G G Sbjct: 971 DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1030 Query: 566 IIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG 624 IG PG PGP+G GP G K PGE G G G G +GP G G G GSPG+ G +G Sbjct: 1031 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1090 Query: 625 -IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALP 683 IG PG+ G++G GE G GP GL G G PG G DG PG G+ G+ G GD A Sbjct: 1091 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1150 Query: 684 LLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA------GEPGKYDSMARKGDIGPRGPP 737 G G + +PG KGE G G PG G GP+GPP Sbjct: 1151 FPGPPGPI-------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1203 Query: 738 GIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAK 797 G G G G KGE G G PG G+ G+ G G G G GPPG G G GP G Sbjct: 1204 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1263 Query: 798 GEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG 857 G KG+ GP G PG PGPPG P G + KG P PGPPGP G G PGP G Sbjct: 1264 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1321 Query: 858 E---PGAMGLPGLEGFPGVKGDRGPAGPPGIA------GMSGKPGAPGPPGVPGEPGERG 908 + PGA G G +G G KG+ G GPPG G +GKPG G G+PG GE+G Sbjct: 1322 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1381 Query: 909 PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKP------GDRGPKGERGDQGIPGDRG 962 G G GP GP G PG+ G G PG++G G P G G +GE+GD+G+PG +G Sbjct: 1382 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1441 Query: 963 SQGERGKPGLTGMKGAIGPMGPP---------GNKGSMGSPGHQ------GPPGSPGIPG 1007 S G +G G+ G G +GP GPP GNKGS G G + GPPGSPG PG Sbjct: 1442 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501 Score = 419 bits (1078), Expect = e-117 Identities = 257/601 (42%), Positives = 303/601 (50%), Gaps = 59/601 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G G G G G G PGE GL GA G G KG+ G +G G+ G G +G G+ Sbjct: 933 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 992 Query: 351 PALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 L G G GLKG GP GPPGP GE+G G GP LPG G QGP GP G++G Sbjct: 993 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1052 Query: 408 RGRRGKTGPPGK---------PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--- 455 G +G GP G+ PGP GP G PG G +G K +KG D+ E G Sbjct: 1053 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG-DKGENGPPG 1111 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KG 507 GL+G G G+ G G GP+GQ+G G+ +G +G G PG IG QG+ KG Sbjct: 1112 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1171 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 E GD GP G G PG +G QG G+ GP+GPPG VG G G G+ G G G PG G Sbjct: 1172 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1231 Query: 566 IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 + GP G G KGEAGPPG + G PG G PG GP+G G G PG G PG+ GP G Sbjct: 1232 VGGPKGERGEKGEAGPPGAA--GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1289 Query: 625 ---------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 G PG+ G GP+GE G GP G G PG G G G G G+ G GP Sbjct: 1290 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1349 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 PG G +G A PG + +G G GE G + + G GP G Sbjct: 1350 PGK------TGPVGP-------QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1396 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 PPG+PG +G GSKGE+G+PG+ G G G QG G G PG G PG G G PGP Sbjct: 1397 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA- 1455 Query: 796 AKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGP 855 G G GPPG PGP GP G G + KG +P PG PGPPG P P Sbjct: 1456 --GPLGPPGPPGLPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508 Query: 856 V 856 + Sbjct: 1509 I 1509 Score = 413 bits (1061), Expect = e-115 Identities = 293/768 (38%), Positives = 356/768 (46%), Gaps = 135/768 (17%) Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPG----SVGPKGQKGEPGEPFTKGEKGDRGE 496 Y NK+ G D + GD GE + P ++ PG P + D E Sbjct: 321 YENKEIDGRDSDLL--VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP----AETDITE 374 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G GE G G P ++ PG+ + GPPG G G G PG QG Sbjct: 375 TSING-HGAYGEKGQKGEPAVV-EPGMLVE----------GPPGPAGPAGIMGPPGLQGP 422 Query: 557 KGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGE------- 607 G GDPG G G PGLPG G GPPG L P G G+ GP E Sbjct: 423 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLM-LPFRYGGDGSKGPTISAQEAQAQAIL 481 Query: 608 -------RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G G GP +G PG +GA+G +G+PG QGPRG+ G PG G PG Sbjct: 482 QQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 539 Query: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 G PG DG G+PG PG GD G F G +PG K ++GE G G PG Sbjct: 540 RGRPGADGGRGMPGEPGAK------GDRG-----FDG--LPGLPGDKGHRGERGPQGPPG 586 Query: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 +G+ G GP G+PG GP+G G RG PG PG+ G G+ G PG G GP G Sbjct: 587 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 646 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY 840 PG G+ G+PGP G G +G GPPG+ GP G PG L + G P + Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG-----------LAGLPGADGPPGH 695 Query: 841 PG------------PPGPPGPKGDPGPVGEPGAMGLPGL---------EGFPGVKGD--- 876 PG PPGP GP G PGP G GA G+ GL +GFPG KGD Sbjct: 696 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 755 Query: 877 ------------RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGK 924 RG GP G G +G G PGP G GE G+ G G G+PG +GP G Sbjct: 756 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815 Query: 925 ---PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 PG G +G GA+G+ GKPG P+G+RG G G RG++G GKPG G G GP Sbjct: 816 TGFPGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 872 Query: 982 MGPPGNKGSMGS------PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 GPPG +G G PG +GPPG PG G+P + Q F+ + Sbjct: 873 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG----------HPGQRGETGFQGKTG 922 Query: 1036 VFLSQLKLPAAMLAAQA-YGRPGPPGKDGLPGPPGDPGPQGY---RGQKGERGEPGI-GL 1090 P ++ Q G GP G+ G PGPPG PG QG G++G +G+PG G+ Sbjct: 923 P-----PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 977 Query: 1091 PGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQR 1138 G G G G PG G PG QG PG G P+ PV +R Sbjct: 978 SGKDGPAGLR--GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1023 Score = 328 bits (842), Expect = 1e-89 Identities = 196/434 (45%), Positives = 229/434 (52%), Gaps = 49/434 (11%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHG---APGFPGQKGEQGFEGSKGETGEKGEQG 346 +KGE G PG GS G KG G PG GL G APG G GE G G +G G+KG++G Sbjct: 1088 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1147 Query: 347 EKGDPA---------LAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPG 391 +G P L G GE G GD+GP GPPGP G +G GP GPP G Sbjct: 1148 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG 1207 Query: 392 SLGIQGPQGPPGK---------------EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQ 436 S+G G +G PG+ +G+RG +G+ GPPG GPPG GPPG G Sbjct: 1208 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1267 Query: 437 TLG--GYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 G G+ + AG G+ GDKGE G PG PG GP G+ G PG P +G G Sbjct: 1268 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1327 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 G G G +G KGE G GPPG G G +G G G G RG PG V GE G+PG Sbjct: 1328 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPG 1384 Query: 553 KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 G G P G +GPPGLPG KG+ G G+ G PGL G G PG +G KG+RGLPG Sbjct: 1385 AAGQDG----PPGPMGPPGLPGLKGDPGSKGEK--GHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 GSPG G GIPG G GP G PG+ GP+G G G+ G G G G G PG Sbjct: 1439 TQGSPGAKGDG--GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1496 Query: 673 PGPPGDPI-ALPLL 685 PGPPG+ I LP+L Sbjct: 1497 PGPPGEVIQPLPIL 1510 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 622 bits (1603), Expect = e-178 Identities = 399/965 (41%), Positives = 466/965 (48%), Gaps = 171/965 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE--------- 341 KG+ G G PG PG KGH+GE G G G PG G +GE G G +G GE Sbjct: 597 KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP 656 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP---PGP------------ 386 +G G G P +AG++G G KG++GP G PGP G++G+ GP PGP Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716 Query: 387 ---PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 P L G G GP G PGKEGQ G +G GPPG GP G PGP G++G G + Sbjct: 717 QGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGS 776 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 K KG D GLKGD+GE G G G GP+G KG G G G GE G Sbjct: 777 KGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGK 836 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGL------KGQQGSAGSMGPRG------PPGDVGLPGE 547 +G G+ G PG GP G G PG KG +G AG GPRG P G G G Sbjct: 837 LGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896 Query: 548 HGIPGKQGIKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKS-LPGEPG------L 592 G PG +G G G PG G GP G PGPKG GPPGK LPG PG Sbjct: 897 TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 956 Query: 593 DGNPGAPGP------RGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQG- 644 G G PGP +GP GE G G G PG GP G G+PG G +G G+PG QG Sbjct: 957 QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016 Query: 645 -----PRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNC 699 P GL G PG G PG G PG G G GPPG P+ P G+ G+ G Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPG-PVGSP--GERGS-----AGTA 1068 Query: 700 -QASVPGLKSNKGEEGGAGE---PGKYDSMARKGDIGPRGPPGIPGREGPKGS------K 749 +PG +G G AGE PG+ G G +GP G+PG GP GS K Sbjct: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128 Query: 750 GERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG---EKGSDGPP 806 GE G PG G KGD+G G PG PG GP G PG+ G G PGP G +G +KG +G Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188 Query: 807 GKPGPPGPPGI-----PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA 861 G PGPPGP G+ P E+ + G + P PGP GP GP G GP G PG+ Sbjct: 1189 GFPGPPGPIGLQGLPGPPGEKGENGDV----GPMGPPGPPGPRGPQGPNGADGPQGPPGS 1244 Query: 862 MGLPGLEGFPGVKGDRGPAGPPGIAGM------------SGKPGAPGPPGVPGEPGERGP 909 +G G G G G+ G GPPG AG+ +G PGA GPPG G PG+ GP Sbjct: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304 Query: 910 VGD---IGFPGPEGPSGKPGINGKDGI---PGAQGIMGKPGDRGPKGERGDQGIPGDRG- 962 G+ +GFPG GP G+PG G+DG+ G G G+PG GP GE G G PG RG Sbjct: 1305 KGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP 1364 Query: 963 --SQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 + G G+ G G KG G GPPG G +G G G PG G+ GIP Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGP--------- 1415 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP--------- 1071 + + LP A A G PGP G GLPG GDP Sbjct: 1416 -----------------VGEQGLPGA---AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHP 1455 Query: 1072 ------GPQGYRGQKGERGEPGI----GLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGPS 1120 GP G +G+KG+RG PG G G G+PG + LG PG PG PGPQGP G Sbjct: 1456 GLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNK 1515 Query: 1121 GRCNP 1125 G P Sbjct: 1516 GSTGP 1520 Score = 587 bits (1514), Expect = e-167 Identities = 373/903 (41%), Positives = 447/903 (49%), Gaps = 100/903 (11%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G+ G PG G+ G +G PG +G G PG PG KG++GF+G G G+KG +GE+G Sbjct: 561 QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620 Query: 351 PALAGLNGENGLKGD---LGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 G G++G++G+ +GP G PG G +G GP G P PG G+ G GPPG +G Sbjct: 621 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGN 680 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G +G+ GPPG+ G PGP G PG QG +G K +G GL G G G P Sbjct: 681 MGPQGEPGPPGQQGNPGPQGLPGPQG---PIGPPGEKGPQGKP-----GLAGLPGADGPP 732 Query: 468 GFPGSVGPKGQKGEPGEPFTKGE------KGDRGEPGVIGSQGVKGEPGDPGPPGLIGSP 521 G PG G G+KG G P +G +G +G GV G +G KGE G+ G PG G Sbjct: 733 GHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDM 792 Query: 522 GLKGQQGSAGSMGPRG---PPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPK 576 GLKG +G G +GPRG P G G G G PG G GEKG G G+ G PG GPK Sbjct: 793 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852 Query: 577 GEAGPPG----KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI------- 625 G G PG G G+ G PG G RGP G RG G G G GP+G Sbjct: 853 GSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPP 912 Query: 626 GIPGRTGAQGPAGEPGIQGPRGLPGLPGT---PGTPGNDGVPGRDGKPGLPGPPGDPIAL 682 G PG G QGP G G GP+G PG PG PG PG G G GK G PGP G Sbjct: 913 GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 972 Query: 683 PLLGDIGALLKNFCGNCQASVP----GLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G+ G + + G+ P GL G+EG G+PG + G G RG PG Sbjct: 973 GPTGETGPIGER--GHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPG 1030 Query: 739 ---IPGREGP---KGSKGERGYPG---IPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTG 789 +PG +G KG +G +G PG PGE+G G G G+PG PGP GPPG G G Sbjct: 1031 ERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKG 1090 Query: 790 HPGPTGAKGEKGSDG---PPGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPG 842 PG G +G G DG P G PGP GP G P + + G KG PG Sbjct: 1091 APGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPG 1150 Query: 843 PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPG 902 PPG GP G PG G G G G +G G KGD G G PG G G G PGPPG G Sbjct: 1151 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1210 Query: 903 EPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR- 961 E G+ GP+G G PGP GP G G +G G PG+ G +G G++G GE G+ G PG+ Sbjct: 1211 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270 Query: 962 --GSQGERGKPGLTGMKGAIGP---MGPPGNKGSMGSPGHQGPPGSPGIPGIPA----DA 1012 G +GERG+ G G GA GP GPPG+ G G+PG G PG PG PG P D Sbjct: 1271 VGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG 1330 Query: 1013 VSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG 1072 V ++ + P + G PGPPGK G PG G G Sbjct: 1331 VGGDKGED------------------GDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG 1372 Query: 1073 PQGYRGQKGERGEPG-------IGLPGSPGLPGTSAL-GLPGS------PGAPGPQGPPG 1118 QG +G KGE G G +G G G PG L G+PG PGA G GPPG Sbjct: 1373 RQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPG 1432 Query: 1119 PSG 1121 P G Sbjct: 1433 PMG 1435 Score = 565 bits (1457), Expect = e-161 Identities = 363/908 (39%), Positives = 431/908 (47%), Gaps = 170/908 (18%) Query: 301 GSPGQKGHKGEPG--ENGL--HGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGL 356 G+ G+KG KGEP E G+ G PG G G G G +G TG G+ G++G P GL Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGL 479 Query: 357 NGENGLKGDLGP------------------------------------HGPPGPKGEKGD 380 G +GL G G GPPGP G Sbjct: 480 PGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGL--- 536 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGG 440 TG PGP PGS G +G G PG +G RG +G GP GKPG G PG G +G+ G Sbjct: 537 TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGA 596 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVI 500 KGD+G GLPG PG G +G++G G P G+ G RGE G I Sbjct: 597 -----------------KGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEI 639 Query: 501 GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEK 560 G +G+ GE G G G G+PG GQ G AG GP GP G++G GE G PG+QG Sbjct: 640 GPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQG----- 694 Query: 561 GDPGGIIGPPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619 +PG P GLPGP+G GPPG+ P G+PGL G PGA GP G G+ G G G+ G Sbjct: 695 -NPG----PQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGP 749 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGD 678 GPQG IG PG G +G G G++G +G G G PG G+ G+ G G+ G GP G+ Sbjct: 750 PGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGE 809 Query: 679 PIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 G + KG G G+PG KG +G G PG Sbjct: 810 D-------------------------GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG 844 Query: 739 IPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG 798 PGR+GPKGS G G+PG GEKG G+ G PG G GPTGP G G G G G KG Sbjct: 845 YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 799 EKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGE 858 G DGPPG PG GP G +G V P GPPGPPG G PG G+ Sbjct: 905 TSGGDGPPGPPGERGPQGP--------------QGPVGFPGPKGPPGPPGKDGLPGHPGQ 950 Query: 859 PGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE---PGERGPVGDIGF 915 G G G G PG G GP GP G G G+ G PGPPG PGE PG G G G Sbjct: 951 RGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGD 1010 Query: 916 PGPEGPSGKPG------INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGK 969 PGP+G SGK G G+ G+PGAQG G G GP+G G G PG+RGS G G Sbjct: 1011 PGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGP 1070 Query: 970 PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGI--------PGIPADAVSFEEIKKY 1021 GL G G GP GP G KG+ G G QGP G G+ P PA + + K Sbjct: 1071 IGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGE 1130 Query: 1022 INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP---------PGDPG 1072 I + P + G GPPG GL GP G+PG Sbjct: 1131 IGE-------------------PGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171 Query: 1073 PQGYRGQKGERGEPG----------IGLPGSPGLPGTSA----LGLPGSPGAPGPQGPPG 1118 P+G +G G++G+ G IGL G PG PG +G G PG PGP+GP G Sbjct: 1172 PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG 1231 Query: 1119 PSGRCNPE 1126 P+G P+ Sbjct: 1232 PNGADGPQ 1239 Score = 531 bits (1369), Expect = e-150 Identities = 345/840 (41%), Positives = 401/840 (47%), Gaps = 144/840 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPG------FPGQKGEQGFEGSKGETGEKGEQ 345 G AGLPGA G PG G +G+ GE G G PG +PG +G +G +G +G G KGE+ Sbjct: 721 GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780 Query: 346 GEKGDPALAG---LNGENGLKGDLGPHG---PPGPKGEKGDTGPPGP------------P 387 GE G P G L G+ G G +GP G P GPKG G TG PGP P Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVP 840 Query: 388 ALPGSLGIQGPQGP---------------------PGKEGQRG------RRGKTGPPGKP 420 LPG G QGP+G PG GQRG RG GP GKP Sbjct: 841 GLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKP 900 Query: 421 GP---------------------------PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 GP PGP GPPG G KD + Sbjct: 901 GPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPG----------KDGLPGHPGQ 950 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEP------GEPFTKGEKGDRGEPGVIGSQGVKG 507 G G +G+TG PG G VGP+G GE G P G G++G PG G +G KG Sbjct: 951 RGE-TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 1009 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 +PG G G G GL+G G G G +G PG G G G PG G GE+G G G Sbjct: 1010 DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1069 Query: 566 IIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG 624 IG PG PGP+G GP G K PGE G G G G +GP G G G GSPG+ G +G Sbjct: 1070 PIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1129 Query: 625 -IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALP 683 IG PG+ G++G GE G GP GL G G PG G DG PG G+ G+ G GD A Sbjct: 1130 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1189 Query: 684 LLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA------GEPGKYDSMARKGDIGPRGPP 737 G G + +PG KGE G G PG G GP+GPP Sbjct: 1190 FPGPPGPI-------GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPP 1242 Query: 738 GIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAK 797 G G G G KGE G G PG G+ G+ G G G G GPPG G G GP G Sbjct: 1243 GSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDD 1302 Query: 798 GEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG 857 G KG+ GP G PG PGPPG P G + KG P PGPPGP G G PGP G Sbjct: 1303 GPKGNPGPVGFPGDPGPPGEP--GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPG 1360 Query: 858 E---PGAMGLPGLEGFPGVKGDRGPAGPPGIA------GMSGKPGAPGPPGVPGEPGERG 908 + PGA G G +G G KG+ G GPPG G +GKPG G G+PG GE+G Sbjct: 1361 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1420 Query: 909 PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKP------GDRGPKGERGDQGIPGDRG 962 G G GP GP G PG+ G G PG++G G P G G +GE+GD+G+PG +G Sbjct: 1421 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQG 1480 Query: 963 SQGERGKPGLTGMKGAIGPMGPP---------GNKGSMGSPGHQ------GPPGSPGIPG 1007 S G +G G+ G G +GP GPP GNKGS G G + GPPGSPG PG Sbjct: 1481 SPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540 Score = 419 bits (1078), Expect = e-117 Identities = 257/601 (42%), Positives = 303/601 (50%), Gaps = 59/601 (9%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G G G G G G PGE GL GA G G KG+ G +G G+ G G +G G+ Sbjct: 972 QGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGE 1031 Query: 351 PALAGLNGENGLKGDLGPHGPPGP---KGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 L G G GLKG GP GPPGP GE+G G GP LPG G QGP GP G++G Sbjct: 1032 RGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGA 1091 Query: 408 RGRRGKTGPPGK---------PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--- 455 G +G GP G+ PGP GP G PG G +G K +KG D+ E G Sbjct: 1092 PGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKG-DKGENGPPG 1150 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KG 507 GL+G G G+ G G GP+GQ+G G+ +G +G G PG IG QG+ KG Sbjct: 1151 PPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKG 1210 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--G 565 E GD GP G G PG +G QG G+ GP+GPPG VG G G G+ G G G PG G Sbjct: 1211 ENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAG 1270 Query: 566 IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG- 624 + GP G G KGEAGPPG + G PG G PG GP+G G G PG G PG+ GP G Sbjct: 1271 VGGPKGERGEKGEAGPPGAA--GPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQ 1328 Query: 625 ---------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 G PG+ G GP+GE G GP G G PG G G G G G+ G GP Sbjct: 1329 DGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGP 1388 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 PG G +G A PG + +G G GE G + + G GP G Sbjct: 1389 PGK------TGPVGP-------QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMG 1435 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 PPG+PG +G GSKGE+G+PG+ G G G QG G G PG G PG G G PGP Sbjct: 1436 PPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA- 1494 Query: 796 AKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGP 855 G G GPPG PGP GP G G + KG +P PG PGPPG P P Sbjct: 1495 --GPLGPPGPPGLPGPQGPKG-----NKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547 Query: 856 V 856 + Sbjct: 1548 I 1548 Score = 413 bits (1061), Expect = e-115 Identities = 293/768 (38%), Positives = 356/768 (46%), Gaps = 135/768 (17%) Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPG----SVGPKGQKGEPGEPFTKGEKGDRGE 496 Y NK+ G D + GD GE + P ++ PG P + D E Sbjct: 360 YENKEIDGRDSDLL--VDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVP----AETDITE 413 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G GE G G P ++ PG+ + GPPG G G G PG QG Sbjct: 414 TSING-HGAYGEKGQKGEPAVV-EPGMLVE----------GPPGPAGPAGIMGPPGLQGP 461 Query: 557 KGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGE------- 607 G GDPG G G PGLPG G GPPG L P G G+ GP E Sbjct: 462 TGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLM-LPFRYGGDGSKGPTISAQEAQAQAIL 520 Query: 608 -------RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G G GP +G PG +GA+G +G+PG QGPRG+ G PG G PG Sbjct: 521 QQARIALRGPPGPMGLTGRPGP--VGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGK 578 Query: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 G PG DG G+PG PG GD G F G +PG K ++GE G G PG Sbjct: 579 RGRPGADGGRGMPGEPGAK------GDRG-----FDG--LPGLPGDKGHRGERGPQGPPG 625 Query: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 +G+ G GP G+PG GP+G G RG PG PG+ G G+ G PG G GP G Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQG 685 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSY 840 PG G+ G+PGP G G +G GPPG+ GP G PG L + G P + Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPG-----------LAGLPGADGPPGH 734 Query: 841 PG------------PPGPPGPKGDPGPVGEPGAMGLPGL---------EGFPGVKGD--- 876 PG PPGP GP G PGP G GA G+ GL +GFPG KGD Sbjct: 735 PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGL 794 Query: 877 ------------RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGK 924 RG GP G G +G G PGP G GE G+ G G G+PG +GP G Sbjct: 795 KGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854 Query: 925 ---PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP 981 PG G +G GA+G+ GKPG P+G+RG G G RG++G GKPG G G GP Sbjct: 855 TGFPGFPGANGEKGARGVAGKPG---PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGP 911 Query: 982 MGPPGNKGSMGS------PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMA 1035 GPPG +G G PG +GPPG PG G+P + Q F+ + Sbjct: 912 PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG----------HPGQRGETGFQGKTG 961 Query: 1036 VFLSQLKLPAAMLAAQA-YGRPGPPGKDGLPGPPGDPGPQGY---RGQKGERGEPGI-GL 1090 P ++ Q G GP G+ G PGPPG PG QG G++G +G+PG G+ Sbjct: 962 P-----PGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGI 1016 Query: 1091 PGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQR 1138 G G G G PG G PG QG PG G P+ PV +R Sbjct: 1017 SGKDGPAGLR--GFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER 1062 Score = 328 bits (842), Expect = 1e-89 Identities = 196/434 (45%), Positives = 229/434 (52%), Gaps = 49/434 (11%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHG---APGFPGQKGEQGFEGSKGETGEKGEQG 346 +KGE G PG GS G KG G PG GL G APG G GE G G +G G+KG++G Sbjct: 1127 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1186 Query: 347 EKGDPA---------LAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPG 391 +G P L G GE G GD+GP GPPGP G +G GP GPP G Sbjct: 1187 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVG 1246 Query: 392 SLGIQGPQGPPGK---------------EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQ 436 S+G G +G PG+ +G+RG +G+ GPPG GPPG GPPG G Sbjct: 1247 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1306 Query: 437 TLG--GYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 G G+ + AG G+ GDKGE G PG PG GP G+ G PG P +G G Sbjct: 1307 NPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 G G G +G KGE G GPPG G G +G G G G RG PG V GE G+PG Sbjct: 1367 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV---GEQGLPG 1423 Query: 553 KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 G G P G +GPPGLPG KG+ G G+ G PGL G G PG +G KG+RGLPG Sbjct: 1424 AAGQDG----PPGPMGPPGLPGLKGDPGSKGEK--GHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 GSPG G GIPG G GP G PG+ GP+G G G+ G G G G G PG Sbjct: 1478 TQGSPGAKGDG--GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGS 1535 Query: 673 PGPPGDPI-ALPLL 685 PGPPG+ I LP+L Sbjct: 1536 PGPPGEVIQPLPIL 1549 Score = 57.0 bits (136), Expect = 1e-07 Identities = 55/235 (23%), Positives = 100/235 (42%), Gaps = 22/235 (9%) Query: 6 PW------KLWLWMSIFLLPASTSVTVRDKTEESCPILRIEGHQLTYDNINKLEVSGFDL 59 PW K WLW A T + + + P+ ++ L + N G Sbjct: 3 PWSSRWKTKRWLWDFTVTTLALTFLFQAREVRGAAPVDVLKA--LDFHN----SPEGISK 56 Query: 60 GDSFSLRRAFCESDKTCFKLGS-ALLIRDTIKIFPKG-LPEEYSVAAMFRVRRNAKKERW 117 F R + T +++ A L T ++FP G PE++S+ + ++ + Sbjct: 57 TTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKGIQS--- 113 Query: 118 FLWQVLNQQNIPQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGIS 177 FL + N+ I QI + V G+ V F+F+ G + + D +WH++ IS Sbjct: 114 FLLSIYNEHGIQQIGVEV--GRSPV-FLFEDHTGKPAPEDYPLFRTVNIADGKWHRVAIS 170 Query: 178 IQSQVISLYMDCNLIARRQTD--EKDTVDFHGRTVIATRASDGKPVDIELHQLKI 230 ++ + +++ +DC + D E+ VD +G TV TR D + + ++ Q I Sbjct: 171 VEKKTVTMIVDCKKKTTKPLDRSERAIVDTNGITVFGTRILDEEVFEGDIQQFLI 225 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 615 bits (1587), Expect = e-176 Identities = 395/957 (41%), Positives = 444/957 (46%), Gaps = 174/957 (18%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G PG PG PG KGH+G PG +G G G PG KGE G G G G G +G G+ Sbjct: 272 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 331 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 G G G +G+ G GP GP G G G PG P PG+ G GP G G EG +G Sbjct: 332 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 391 Query: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470 RG+ G PG PGP G G PG GI A G G G G PGFP Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPG-----------------AKGSAGAPGIAGAPGFP 434 Query: 471 GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP---PGLIGSPGLKGQQ 527 G GP G +G G KG+ G+ G G G QG KGEPG GP PG G G +G + Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494 Query: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK--- 584 G G +GP GPPG+ G PG G PG+ G+ G KG PG GP GL GPKG G PG+ Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER-GPSGLAGPKGANGDPGRPGE 553 Query: 585 -SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI----GIPGRTGAQGPAGE 639 LPG GL G PG GP+G G G PG G PG GPQG G+ G G +G GE Sbjct: 554 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 613 Query: 640 PGIQGPRGLPGLPGTPGTPGNDG---------------------VPGRDGKPGLPGPPGD 678 PG G +GLPG PG G PG DG PG G GLPGPPG Sbjct: 614 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 673 Query: 679 PIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 P GD G +A PGL +GE G GE G S +G GPRG PG Sbjct: 674 PGEGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERG---SPGAQGLQGPRGLPG 723 Query: 739 IPGREGPKGSKG------------------ERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 PG +GPKG+ G ERG GI G KGD G G G GAPG G Sbjct: 724 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 783 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPG---------------KPGPPGPPGIPFNE---- 821 GL G G PGP GA GEKG GPPG + GPPGP G Sbjct: 784 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 843 Query: 822 ---RNGMSSLYKIKGGVNVPSYPGP---PGPPGPKGDPGPVGEPGAMGLPGLEGFPGV-- 873 G KG P GP PGP GP G GP G GA G PG GFPG Sbjct: 844 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG 903 Query: 874 -------KGDRGPAGPPGIAGMSGKPGA---PGPPGVPGEPGERGPVG---DIGFPGPEG 920 G+ GP GPPG +G G GA GPPG GEPG +GP G + G PG +G Sbjct: 904 RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 963 Query: 921 PSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIG 980 PSG G G G+ G +GI+G PG RG ERG G+PG G G++G PG +G +G G Sbjct: 964 PSGAEGPPGPQGLAGQRGIVGLPGQRG---ERGFPGLPGPSGEPGKQGAPGASGDRGPPG 1020 Query: 981 PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQ 1040 P+GPPG G G PG +G PG+ G PG A + +R Sbjct: 1021 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAA---------------GVKGDR------- 1058 Query: 1041 LKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG------------------------PQGY 1076 A A G PGPPG G GP G G PQG Sbjct: 1059 ----GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114 Query: 1077 RGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPV 1132 RG KGE GEPG GL G G G GLPG PG G QG GP+G P PV Sbjct: 1115 RGDKGEAGEPGERGLKGHRGFTGLQ--GLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1169 Score = 591 bits (1523), Expect = e-168 Identities = 378/935 (40%), Positives = 445/935 (47%), Gaps = 149/935 (15%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G+ G G G+PG +G GEPG G G PG PG G G G+ G + G Sbjct: 134 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 193 Query: 351 PALAGLNGENGLKGDLGPHGP---PGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 L + G G G GP GP PGP+G +G+ G PG P + G +G +GP GPPGK G Sbjct: 194 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G GK PGK G GPPGP G +G T G K ++G GL G KGE G P Sbjct: 254 DGEAGK---PGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYP-----GLDGAKGEAGAP 305 Query: 468 GFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVK---GEPGDPGPPGLIGS---- 520 G G G G+ G PG +G G+RG G G+ G + G+PG GPPG +G Sbjct: 306 GVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGP 365 Query: 521 --PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGE 578 PG G +G AG G RGP G G GE G PG G G G+P G G+PG KG Sbjct: 366 GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGS 421 Query: 579 AGPPG-KSLPGEPGLDGNP---GAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGA 633 AG PG PG PG G P GA GP GPKG+ G PG+ G G+ GP+G G G GA Sbjct: 422 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 481 Query: 634 QGPAGEPGIQGPRGLP------GLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGD 687 GPAGE G +G RG P G PG G PGN G PG+DG G G PG+ L G Sbjct: 482 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541 Query: 688 IGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKG 747 GA N PG G G G PG +G +GP G PG GR GP G Sbjct: 542 KGA-------NGDPGRPGEPGLPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPG 591 Query: 748 SKGERGYPGI------------PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 +G RG PG+ PG+ G++GL G PG+ G PG G G G G GP G Sbjct: 592 PQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAG 651 Query: 796 AKGEKGSDGP------PGKPGPPGPPGIPFNE----RNGMSSLYKIKGGVNVP------- 838 +GE+G+ GP PG PGPPG G P ++ G L +G P Sbjct: 652 ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG 711 Query: 839 --------SYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP---------GVKGDR---- 877 PG PG GPKG GP G PGA G PGL+G P G KGDR Sbjct: 712 AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 771 Query: 878 -----------------GPAGPPGIAGMSGKPGAPGPP---------GVPGEPGERGPVG 911 GP GPPG AG +G+ G GPP G PGE GE GP G Sbjct: 772 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG 831 Query: 912 DIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ---GIPGDRGSQGERG 968 GF GP G G+PG G+ G G +G G PG +GP G G Q G+ G +G++G +G Sbjct: 832 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 891 Query: 969 KPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLR 1028 PG TG GA G +GPPG+ G+ G PG GP G G G D+ Sbjct: 892 PPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP-------------- 937 Query: 1029 IFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG- 1087 + P A G G PG DG G G PGPQG GQ+G G PG Sbjct: 938 ---------PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 988 Query: 1088 IGLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGPSG 1121 G G PGLPG S G G+PGA G +GPPGP G Sbjct: 989 RGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 1023 Score = 590 bits (1520), Expect = e-168 Identities = 388/993 (39%), Positives = 449/993 (45%), Gaps = 218/993 (21%) Query: 296 LPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAG 355 L A G PG KG KGEPG+ + G G G QG G +G G++G++GEKG P G Sbjct: 93 LATASGQPGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG 150 Query: 356 LNGENGLKGDLGPHGPPGPKGE---------------------------KGDTGPPGPPA 388 +GE G G+ GP GPPGP G +G GP GP Sbjct: 151 RDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG 210 Query: 389 LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKG 448 PG G GPQG G G+ G G +GP G GPPGPPG PG Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG------------------ 252 Query: 449 NDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQ 503 D+ EAG G +G G G GFPG+ G G KG G P G KG+ G PGV G Sbjct: 253 -DDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311 Query: 504 GVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG---------PRGPPGDVGLPGEHGIPGKQ 554 G GE G PGP G G PG +G+ G AG+ G P GPPG VG G G PG Sbjct: 312 GSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAP 371 Query: 555 GIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLP-------------------GEPGLDGN 595 G KGE G P G GP G GP+GE G PG P G PG+ G Sbjct: 372 GAKGEAG-PTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGA 430 Query: 596 PGAPGPRGP------------KGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGI 642 PG PGPRGP KG+ G PG+ G G+ GP+G G G GA GPAGE G Sbjct: 431 PGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK 490 Query: 643 QGPRGLPG------LPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFC 696 +G RG PG PG G PGN G PG+DG G G PG+ L G GA Sbjct: 491 RGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA------ 544 Query: 697 GNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPG 756 N PG G G G PG +G +GP G PG GR GP G +G RG PG Sbjct: 545 -NGDPGRPGEPGLPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPG 600 Query: 757 I------------PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDG 804 + PG+ G++GL G PG+ G PG G G G G GP G +GE+G+ G Sbjct: 601 VMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG 660 Query: 805 P------PGKPGPPGPPGIPFNE----RNGMSSLYKIKGGVNVPS--------------- 839 P PG PGPPG G P ++ G L +G P Sbjct: 661 PSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720 Query: 840 YPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGV---------KGDRG------------ 878 PG PG GPKG GP G PGA G PGL+G PG KGDRG Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780 Query: 879 ---------PAGPPGIAGMSGKPGAPGPPG---------VPGEPGERGPVGDIGFPGPEG 920 P GPPG AG +G+ G GPPG PGE GE GP G GF GP G Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPG 840 Query: 921 PSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQG---IPGDRGSQGERGKPGLTGMKG 977 G+PG G+ G G +G G PG +GP G G QG + G +G++G +G PG TG G Sbjct: 841 ADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900 Query: 978 AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVF 1037 A G +GPPG+ G+ G PG GP G G G D+ + Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE----------------- 943 Query: 1038 LSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGL 1096 P A G G PG DG G G PGPQG GQ+G G PG G G PGL Sbjct: 944 ------PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGL 997 Query: 1097 PGTSA----LGLPGSPGAPGPQGPPGPSGRCNP 1125 PG S G PG+ G GP GP GP G P Sbjct: 998 PGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP 1030 Score = 528 bits (1361), Expect = e-150 Identities = 329/781 (42%), Positives = 384/781 (49%), Gaps = 86/781 (11%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 PA +E K + P G G G PG G G++G PG++GL G G PG++G G G Sbjct: 484 PAGEEGKRGARGEP--GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGI 395 KG G+ G GE G P GL G G G G GP G GE G GPPGP G G+ Sbjct: 542 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601 Query: 396 QGPQGPPGKEGQRGRRGKTGPPGKPG---------------PPGPPGPPGIQGIHQTLG- 439 G GP G G+ G+ G+ G PG PG PPGP GP G +G G Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661 Query: 440 -GYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE---PFTKGEKGDRG 495 G+ E GG GD+G G G PG VGP+G++G PGE P +G +G RG Sbjct: 662 SGFQGLPGPPGPPGE-GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720 Query: 496 EPGVIGSQGVKGEPGDPGPPGLIGSPGLKG---QQGSAGSMGPRGPPGDVGLPGEHGIPG 552 PG G+ G KG G GPPG G PGL+G ++G+AG GP+G GDVG G G PG Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780 Query: 553 KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-------KSLPGEPGLDGNPGAPGPRGPK 605 K G +G G P G GP G G KGE GPPG + PGE G G PG G GP Sbjct: 781 KDGGRGLTG-PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 839 Query: 606 GERGLPGVHGSPGDIGPQG-IGIPGR---TGAQGPAGEPGIQGPRGLPGLPGTPGTPGND 661 G G PG G G+ G +G G PG +GA GP G G+ GP+G G G PG G Sbjct: 840 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 662 GVPGRDGKPGL---PGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G GR G PG PGPPG P G GA + PG G +G AG Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-------RGDSGPPGRAGEPGLQGPAGP 952 Query: 719 PGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGP 778 PG+ KG+ G GP G G GP+G G+RG G+PG++G+ G G+PG G PG Sbjct: 953 PGE------KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 1006 Query: 779 TGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNV 837 G PG G G PGP G G G G PG+ G PG G P + G+ G V Sbjct: 1007 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 1066 Query: 838 PSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGP 897 P PGPPG PGP G G G+ G G +G GP+GP G G+ G G G Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGD---------RGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1117 Query: 898 PGVPGEPGERGPVGDIGF------PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGE 951 G GEPGERG G GF PGP GPSG G +G G G G PG GP G+ Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP---AGPSGPRGPPGPVGPSGK 1174 Query: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPAD 1011 G GIPG G G RG+ G T GP GPPGN PG GPPG PG PGI Sbjct: 1175 DGANGIPGPIGPPGPRGRSGET------GPAGPPGN------PGPPGPPGPPG-PGIDMS 1221 Query: 1012 A 1012 A Sbjct: 1222 A 1222 Score = 484 bits (1247), Expect = e-136 Identities = 303/726 (41%), Positives = 341/726 (46%), Gaps = 140/726 (19%) Query: 464 TGLPGFPGSVGPKGQKGEP-------------------GEPFTKGEKGDRGEPGVIGSQG 504 T L G GPKGQKGEP GE +G++GD+GE G G +G Sbjct: 91 TDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG 150 Query: 505 VKGE------PGDPGPPGLIGSPGLKG---------------------QQGSAGSMGPRG 537 GE PG PGPPG G PGL G QG G MGPRG Sbjct: 151 RDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG 210 Query: 538 PPGDVGLPGEHGIPGKQGIKGEKG-----DPGGIIGPPGLPGPKGEAGPPGKS----LPG 588 PPG G PG G G G GE G P G GPPG PG GEAG PGK+ PG Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 270 Query: 589 EPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGL 648 G G PG PG G KG RG PG+ G+ G+ G G+ G +G+ G G PG GPRGL Sbjct: 271 PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAP--GVKGESGSPGENGSPGPMGPRGL 328 Query: 649 PGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKS 708 PG G G G G G DG+PG GPPG +G G PG Sbjct: 329 PGERGRTGPAGAAGARGNDGQPGPAGPPGP------VGPAGG----------PGFPGAPG 372 Query: 709 NKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQG 768 KGE G G G +G GPRG PG PG GP G+ G G GIPG KG G G Sbjct: 373 AKGEAGPTGARGP------EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE------KGSDGPPGKPGPPGPPGIPFNER 822 I G PG PGP GPPG G TG GP G GE KG GP G+PGP GP G P Sbjct: 427 IAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP---- 482 Query: 823 NGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGP 882 G + +G P GP GPPG +G PG G PG GL G +G PG +G G AGP Sbjct: 483 -GPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541 Query: 883 PGIAGMSGKPGAPGPP---GVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 G G G+PG PG P G+ G PG+ GP G +G G G G+PG G G G G+ Sbjct: 542 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601 Query: 940 MGKPGDRGPKGE---RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH 996 MG PG +G GE G++G+PG G +G GK G TG G GP GP G +G G+PG Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661 Query: 997 QGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRP 1056 G G PG PG P + G+P Sbjct: 662 SGFQGLPGPPGPPGEG-----------------------------------------GKP 680 Query: 1057 GPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQG 1115 G G G G PG GP+G RG GERG PG GL G GLPGT G G GA GP G Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP--GTDGPKGASGPAG 738 Query: 1116 PPGPSG 1121 PPG G Sbjct: 739 PPGAQG 744 Score = 394 bits (1013), Expect = e-109 Identities = 263/673 (39%), Positives = 304/673 (45%), Gaps = 138/673 (20%) Query: 563 PGGIIGPPGLPGPKGEAGPPG--------------------------------KSLP--- 587 P + G PGPKG+ G PG K P Sbjct: 90 PTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPR 149 Query: 588 ---GEPGLDGNPGAPGPRGPKGERGLPG---------------------VHGSPGDIGPQ 623 GEPG GNPG PGP GP G GL G + G G +GP+ Sbjct: 150 GRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPR 209 Query: 624 G----IGIPGRTGAQ---GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPP 676 G G PG G Q G GEPG+ GP G G PG PG PG+DG G+ GK G GPP Sbjct: 210 GPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269 Query: 677 GDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGP 736 G A G G L G+ PGL KGE G G G+ S G GP GP Sbjct: 270 GPQGARGFPGTPG--LPGVKGH--RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 325 Query: 737 PGIP---GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 G+P GR GP G+ G RG G PG G G G G PG PG G G G TG GP Sbjct: 326 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385 Query: 794 TGAKGEKGSDGPPGKPGPPGPPGIPFNER-NGMSSLYKIKGGVNVPSYPGPPGPPGPKGD 852 GA+G +G G PG PGP G G P + G G P +PGP GPPGP+G Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGA 445 Query: 853 PGPVGEPGAMGLPGLEGF---PGVKGDRGPAGP---PGIAGMSGKPGAPGPP---GVPGE 903 GP+G G G PG+ GF G KG+ GPAGP PG AG GK GA G P G G Sbjct: 446 TGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGP 505 Query: 904 PGERGPVGDIGFP---------------------GPEGPSGKPGINGKDGIPGAQGIMGK 942 PGERG G+ GFP GP+G +G PG G+ G+PGA+G+ G+ Sbjct: 506 PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 565 Query: 943 PGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGS 1002 PGD GP+G+ G G PG+ G G G G G G +G GP G G G G +G PG+ Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKD 1062 PG+ G+P E A PA Q G PGP G Sbjct: 626 PGLRGLPGKD------------------GETGAAGPPGPAGPAGERGEQ--GAPGPSGFQ 665 Query: 1063 GLPGPPGDPGPQGYRGQK---GERGEPGI-------GLPGSPGLPGTSAL----GLPGSP 1108 GLPGPPG PG G G + GE G PG+ G PG G PG L GLPG+P Sbjct: 666 GLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTP 725 Query: 1109 GAPGPQGPPGPSG 1121 G GP+G GP+G Sbjct: 726 GTDGPKGASGPAG 738 Score = 315 bits (806), Expect = 2e-85 Identities = 215/573 (37%), Positives = 244/573 (42%), Gaps = 92/573 (16%) Query: 636 PAGEPGIQGPRGLPGLPGTPGTPGN----------------------------------- 660 P GE P L G PG G Sbjct: 81 PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140 Query: 661 -----------DGVPGRDGKPGLPGPPGDPIALPLLGDIGALL----KNFCGNCQASV-- 703 DG PG G PG PGPPG P L G+ A + G Q V Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200 Query: 704 -----------PGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGR---EGPKGSK 749 PG G +G G PG+ G +GPRGPPG PG+ +G G Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260 Query: 750 GERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKP 809 G+ G G PG +G G G PG+PG G G PGL G G G G KGE GS G G P Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320 Query: 810 GPPGPPGIPFNE-RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGA------M 862 GP GP G+P R G + +G P GPPGP GP G PG G PGA Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPT 380 Query: 863 GLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPS 922 G G EG G +G+ G G PG AG SG PG G PG G G G G GFPGP GP Sbjct: 381 GARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 440 Query: 923 GKPGIN---GKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAI 979 G G G G G GI G G++GPKGE G G G G GE GK G G G + Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV 500 Query: 980 GPMGPPGNKGSMGSPGHQGPPGSPGIPGIPAD-AVSFEEIKKYINQEVLRIFEERMAVFL 1038 GP+GPPG +G+ G+ G G G G G P + S K N + R E + Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGAR 560 Query: 1039 SQLKLPAAMLAAQAYGRPGPPGKDGLPGPP------GDPGPQGYRGQKGERGEPG----I 1088 P G G PG+DG PGPP G PG G+ G KG GEPG Sbjct: 561 GLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEK 620 Query: 1089 GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 GLPG+PGL GLPG G G GPPGP+G Sbjct: 621 GLPGAPGL-----RGLPGKDGETGAAGPPGPAG 648 Score = 266 bits (681), Expect = 6e-71 Identities = 175/461 (37%), Positives = 202/461 (43%), Gaps = 73/461 (15%) Query: 696 CGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP 755 C C + G +G GEPG K +GP+GPPG P+G GE+G Sbjct: 86 CPICPTDLATASGQPGPKGQKGEPGDI-----KDIVGPKGPPG------PQGPAGEQGPR 134 Query: 756 GIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPP 815 G G+KG++G APGP G G G G+PGP PG PGPPGPP Sbjct: 135 GDRGDKGEKG---------APGPRGRDGEPGTPGNPGP------------PGPPGPPGPP 173 Query: 816 GIPFNERNGMSSLYKIK-GGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGL---PGLEGFP 871 G+ N M+ + K GG + GP GP GP+G PGP G PG G PG G P Sbjct: 174 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEP 233 Query: 872 GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKD 931 GV G GP GPPG G G G G PG GE G GP G GFPG G G G G Sbjct: 234 GVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYP 293 Query: 932 GIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSM 991 G+ GA+G G PG +G G G+ G PG G +G G+ G TG GA G G G G Sbjct: 294 GLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G PG GP G PG PG P + + + P A Sbjct: 354 GPPGPVGPAGGPGFPGAPG---------------------AKGEAGPTGARGPEG--AQG 390 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPG----TSALG 1103 G PG PG G G G+PG G G KG G PGI G PG G PG T LG Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450 Query: 1104 LPGSPGAPG------PQGPPGPSGRCNPEDCLYPVSHAHQR 1138 G G PG QGP G G P+ P +R Sbjct: 451 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKR 491 Score = 231 bits (589), Expect = 3e-60 Identities = 139/318 (43%), Positives = 161/318 (50%), Gaps = 28/318 (8%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G AG PG G G G KGEPG++G GA G PG +G G G G G++GE+G G P Sbjct: 939 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRR 411 +G G+ G G G GPPGP G G TGP G P GS G GPPG++G G + Sbjct: 999 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS---PGADGPPGRDGAAGVK 1055 Query: 412 GKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDKGETGLPGF 469 G G G G PG PGPPG G G K D EAG G G G G G Sbjct: 1056 GDRGETGAVGAPGAPGPPGSPGPAGPTG-------KQGDRGEAGAQGPMGPSGPAGARGI 1108 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529 G GP+G KGE GEP GE+G +G G G QG+ G PG G G G G G +G Sbjct: 1109 QGPQGPRGDKGEAGEP---GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1165 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G +GP G G G+PG G PG +G GE G GPPG PGP G GPPG Sbjct: 1166 PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP----AGPPGNPGPPGPPGPPG------ 1215 Query: 590 PGLDGNPGA---PGPRGP 604 PG+D + A P +GP Sbjct: 1216 PGIDMSAFAGLGPREKGP 1233 Score = 108 bits (269), Expect = 4e-23 Identities = 67/182 (36%), Positives = 80/182 (43%), Gaps = 41/182 (22%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQK---GEQGFEGSKGETGEKGEQGEK 348 G G+ G G G KG GEPGE GL G GF G + G G G +G +G G G + Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQR 408 G P G +G++G G GP GPPGP+G G+TGP GPP PG Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG----------------- 1206 Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND-------EHEAGGLKGDK 461 PPGPPGPPG GI + KG D + AGGL+ Sbjct: 1207 -------------PPGPPGPPG-PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHD 1252 Query: 462 GE 463 E Sbjct: 1253 AE 1254 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 615 bits (1587), Expect = e-176 Identities = 395/957 (41%), Positives = 444/957 (46%), Gaps = 174/957 (18%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G PG PG PG KGH+G PG +G G G PG KGE G G G G G +G G+ Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 G G G +G+ G GP GP G G G PG P PG+ G GP G G EG +G Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGP 322 Query: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470 RG+ G PG PGP G G PG GI A G G G G PGFP Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPG-----------------AKGSAGAPGIAGAPGFP 365 Query: 471 GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP---PGLIGSPGLKGQQ 527 G GP G +G G KG+ G+ G G G QG KGEPG GP PG G G +G + Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425 Query: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK--- 584 G G +GP GPPG+ G PG G PG+ G+ G KG PG GP GL GPKG G PG+ Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER-GPSGLAGPKGANGDPGRPGE 484 Query: 585 -SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI----GIPGRTGAQGPAGE 639 LPG GL G PG GP+G G G PG G PG GPQG G+ G G +G GE Sbjct: 485 PGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGE 544 Query: 640 PGIQGPRGLPGLPGTPGTPGNDG---------------------VPGRDGKPGLPGPPGD 678 PG G +GLPG PG G PG DG PG G GLPGPPG Sbjct: 545 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 604 Query: 679 PIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 P GD G +A PGL +GE G GE G S +G GPRG PG Sbjct: 605 PGEGGKPGDQGV-------PGEAGAPGLVGPRGERGFPGERG---SPGAQGLQGPRGLPG 654 Query: 739 IPGREGPKGSKG------------------ERGYPGIPGEKGDEGLQGIPGIPGAPGPTG 780 PG +GPKG+ G ERG GI G KGD G G G GAPG G Sbjct: 655 TPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDG 714 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPG---------------KPGPPGPPGIPFNE---- 821 GL G G PGP GA GEKG GPPG + GPPGP G Sbjct: 715 GRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG 774 Query: 822 ---RNGMSSLYKIKGGVNVPSYPGP---PGPPGPKGDPGPVGEPGAMGLPGLEGFPGV-- 873 G KG P GP PGP GP G GP G GA G PG GFPG Sbjct: 775 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG 834 Query: 874 -------KGDRGPAGPPGIAGMSGKPGA---PGPPGVPGEPGERGPVG---DIGFPGPEG 920 G+ GP GPPG +G G GA GPPG GEPG +GP G + G PG +G Sbjct: 835 RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDG 894 Query: 921 PSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIG 980 PSG G G G+ G +GI+G PG RG ERG G+PG G G++G PG +G +G G Sbjct: 895 PSGAEGPPGPQGLAGQRGIVGLPGQRG---ERGFPGLPGPSGEPGKQGAPGASGDRGPPG 951 Query: 981 PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQ 1040 P+GPPG G G PG +G PG+ G PG A + +R Sbjct: 952 PVGPPGLTGPAGEPGREGSPGADGPPGRDGAA---------------GVKGDR------- 989 Query: 1041 LKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG------------------------PQGY 1076 A A G PGPPG G GP G G PQG Sbjct: 990 ----GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045 Query: 1077 RGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPV 1132 RG KGE GEPG GL G G G GLPG PG G QG GP+G P PV Sbjct: 1046 RGDKGEAGEPGERGLKGHRGFTGLQ--GLPGPPGPSGDQGASGPAGPSGPRGPPGPV 1100 Score = 591 bits (1523), Expect = e-168 Identities = 376/932 (40%), Positives = 441/932 (47%), Gaps = 143/932 (15%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G+ G G G+PG +G GEPG G G PG PG G G G+ G + G Sbjct: 65 RGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGG 124 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 L + G G G GP GP G G +G G PG P PG G GP+GPPG G+ G Sbjct: 125 AQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 Query: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470 G+ G PGK G GPPGP G +G T G K ++G GL G KGE G PG Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYP-----GLDGAKGEAGAPGVK 239 Query: 471 GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVK---GEPGDPGPPGLIGS------P 521 G G G+ G PG +G G+RG G G+ G + G+PG GPPG +G P Sbjct: 240 GESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFP 299 Query: 522 GLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGP 581 G G +G AG G RGP G G GE G PG G G G+P G G+PG KG AG Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNP----GTDGIPGAKGSAGA 355 Query: 582 PG-KSLPGEPGLDGNP---GAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGP 636 PG PG PG G P GA GP GPKG+ G PG+ G G+ GP+G G G GA GP Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGP 415 Query: 637 AGEPGIQGPRGLP------GLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGA 690 AGE G +G RG P G PG G PGN G PG+DG G G PG+ L G GA Sbjct: 416 AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 475 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 N PG G G G PG +G +GP G PG GR GP G +G Sbjct: 476 -------NGDPGRPGEPGLPGARGLTGRPG---DAGPQGKVGPSGAPGEDGRPGPPGPQG 525 Query: 751 ERGYPGI------------PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG 798 RG PG+ PG+ G++GL G PG+ G PG G G G G GP G +G Sbjct: 526 ARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERG 585 Query: 799 EKGSDGP------PGKPGPPGPPGIPFNE----RNGMSSLYKIKGGVNVP---------- 838 E+G+ GP PG PGPPG G P ++ G L +G P Sbjct: 586 EQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 645 Query: 839 -----SYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP---------GVKGDR------- 877 PG PG GPKG GP G PGA G PGL+G P G KGDR Sbjct: 646 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKG 705 Query: 878 --------------GPAGPPGIAGMSGKPGAPGPP---------GVPGEPGERGPVGDIG 914 GP GPPG AG +G+ G GPP G PGE GE GP G G Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAG 765 Query: 915 FPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ---GIPGDRGSQGERGKPG 971 F GP G G+PG G+ G G +G G PG +GP G G Q G+ G +G++G +G PG Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPG 825 Query: 972 LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFE 1031 TG GA G +GPPG+ G+ G PG GP G G G D+ Sbjct: 826 ATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGP----------------- 868 Query: 1032 ERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGL 1090 + P A G G PG DG G G PGPQG GQ+G G PG G Sbjct: 869 ------PGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGE 922 Query: 1091 PGSPGLPGTSA-LGLPGSPGAPGPQGPPGPSG 1121 G PGLPG S G G+PGA G +GPPGP G Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVG 954 Score = 574 bits (1480), Expect = e-163 Identities = 362/892 (40%), Positives = 421/892 (47%), Gaps = 130/892 (14%) Query: 303 PGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGL 362 PG KG KGEPG+ G KG G +G GE G +G++G+KG+ G G +G Sbjct: 31 PGPKGQKGEPGD-----IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 85 Query: 363 KGDLGPHGPPGPKGEKGDTGPPGPPALPGS-----------------LGI-QGPQGPPGK 404 G G GPPGP G PPGPP L G+ LG+ QGP GP G Sbjct: 86 PGTPGNPGPPGPPG------PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGP 139 Query: 405 EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG-----GL 457 G G G GP G G PG PG PG+ G +G G K D+ EAG G Sbjct: 140 RGPPGPAGAPGPQGFQGNPGEPGEPGVSG---PMGPRGPPGPPGKPGDDGEAGKPGKAGE 196 Query: 458 KGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGL 517 +G G G GFPG+ G G KG G P G KG+ G PGV G G GE G PGP G Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGP 256 Query: 518 IGSPGLKGQQGSAGSMG---------PRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIG 568 G PG +G+ G AG+ G P GPPG VG G G PG G KGE G P G G Sbjct: 257 RGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG-PTGARG 315 Query: 569 PPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI--- 625 P G GP+GE G PG PG G GNPG G G KG G PG+ G+PG GP+G Sbjct: 316 PEGAQGPRGEPGTPGS--PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP 373 Query: 626 -GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684 G G G +G GEPGI G +G G G PG G G PG G+ G G G+P + Sbjct: 374 QGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGP 433 Query: 685 LGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREG 744 +G G + PG + G++G AG G G GP+G G PGR G Sbjct: 434 IGPPG----------ERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPG 483 Query: 745 PKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDG 804 G G RG G PG+ G +G G G PG G GPPG G G PG G G KG++G Sbjct: 484 EPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANG 543 Query: 805 PPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGP------------------ 846 PGK G G PG P G+ L G PGP GP Sbjct: 544 EPGKAGEKGLPGAP-----GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL 598 Query: 847 PGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGE 906 PGP G PG G+PG G+PG G PG+ G RG G PG G G G GP G+PG PG Sbjct: 599 PGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT 658 Query: 907 RGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQ-- 964 GP G G GP G G PG+ G G GA GI G GDRG GE+G +G PG G + Sbjct: 659 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718 Query: 965 ----GERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ---GPPGSPGIPGIP-ADAVSFE 1016 G G G G KG +GP GP G+ G+ G+PG + GPPG G G P AD Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADG---- 774 Query: 1017 EIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGY 1076 P A G+ G G G GP G PGPQG Sbjct: 775 --------------------------QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGP 808 Query: 1077 RGQKGERGEPGI-GLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGPSGRCNPE 1126 G G +G G G PG+ G PG + +G PGS G PGP GPPGPSG+ P+ Sbjct: 809 TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPK 860 Score = 528 bits (1361), Expect = e-150 Identities = 329/781 (42%), Positives = 384/781 (49%), Gaps = 86/781 (11%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 PA +E K + P G G G PG G G++G PG++GL G G PG++G G G Sbjct: 415 PAGEEGKRGARGEP--GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGI 395 KG G+ G GE G P GL G G G G GP G GE G GPPGP G G+ Sbjct: 473 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532 Query: 396 QGPQGPPGKEGQRGRRGKTGPPGKPG---------------PPGPPGPPGIQGIHQTLG- 439 G GP G G+ G+ G+ G PG PG PPGP GP G +G G Sbjct: 533 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592 Query: 440 -GYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE---PFTKGEKGDRG 495 G+ E GG GD+G G G PG VGP+G++G PGE P +G +G RG Sbjct: 593 SGFQGLPGPPGPPGE-GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651 Query: 496 EPGVIGSQGVKGEPGDPGPPGLIGSPGLKG---QQGSAGSMGPRGPPGDVGLPGEHGIPG 552 PG G+ G KG G GPPG G PGL+G ++G+AG GP+G GDVG G G PG Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711 Query: 553 KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG-------KSLPGEPGLDGNPGAPGPRGPK 605 K G +G G P G GP G G KGE GPPG + PGE G G PG G GP Sbjct: 712 KDGGRGLTG-PIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPP 770 Query: 606 GERGLPGVHGSPGDIGPQG-IGIPGR---TGAQGPAGEPGIQGPRGLPGLPGTPGTPGND 661 G G PG G G+ G +G G PG +GA GP G G+ GP+G G G PG G Sbjct: 771 GADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 830 Query: 662 GVPGRDGKPGL---PGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGE 718 G GR G PG PGPPG P G GA + PG G +G AG Sbjct: 831 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA-------RGDSGPPGRAGEPGLQGPAGP 883 Query: 719 PGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGP 778 PG+ KG+ G GP G G GP+G G+RG G+PG++G+ G G+PG G PG Sbjct: 884 PGE------KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGK 937 Query: 779 TGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNV 837 G PG G G PGP G G G G PG+ G PG G P + G+ G V Sbjct: 938 QGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGA 997 Query: 838 PSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGP 897 P PGPPG PGP G G G+ G G +G GP+GP G G+ G G G Sbjct: 998 PGAPGPPGSPGPAGPTGKQGD---------RGEAGAQGPMGPSGPAGARGIQGPQGPRGD 1048 Query: 898 PGVPGEPGERGPVGDIGF------PGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGE 951 G GEPGERG G GF PGP GPSG G +G G G G PG GP G+ Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGP---AGPSGPRGPPGPVGPSGK 1105 Query: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPAD 1011 G GIPG G G RG+ G T GP GPPGN PG GPPG PG PGI Sbjct: 1106 DGANGIPGPIGPPGPRGRSGET------GPAGPPGN------PGPPGPPGPPG-PGIDMS 1152 Query: 1012 A 1012 A Sbjct: 1153 A 1153 Score = 265 bits (678), Expect = 1e-70 Identities = 182/483 (37%), Positives = 211/483 (43%), Gaps = 83/483 (17%) Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 G P + L LL + A+L+ C PG K KGE G K +GP Sbjct: 5 GAPQTLVLLTLL--VAAVLR--CQGQDVRQPGPKGQKGEPGDI-----------KDIVGP 49 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 +GPPG P+G GE+G G G+KG++G APGP G G G G+PGP Sbjct: 50 KGPPG------PQGPAGEQGPRGDRGDKGEKG---------APGPRGRDGEPGTPGNPGP 94 Query: 794 TGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIK-GGVNVPSYPGPPGPPGPKGD 852 PG PGPPGPPG+ N M+ + K GG + GP GP GP+G Sbjct: 95 ------------PGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGP 142 Query: 853 PGPVGEPGAMGL---PGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGP 909 PGP G PG G PG G PGV G GP GPPG G G G G PG GE G GP Sbjct: 143 PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGP 202 Query: 910 VGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGK 969 G GFPG G G G G G+ GA+G G PG +G G G+ G PG G +G G+ Sbjct: 203 QGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGE 262 Query: 970 PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRI 1029 G TG GA G G G G G PG GP G PG PG P Sbjct: 263 RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPG------------------- 303 Query: 1030 FEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI- 1088 + + + P A G PG PG G G G+PG G G KG G PGI Sbjct: 304 --AKGEAGPTGARGPEG--AQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359 Query: 1089 ---GLPGSPGLPG----TSALGLPGSPGAPG------PQGPPGPSGRCNPEDCLYPVSHA 1135 G PG G PG T LG G G PG QGP G G P+ P Sbjct: 360 GAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEE 419 Query: 1136 HQR 1138 +R Sbjct: 420 GKR 422 Score = 231 bits (589), Expect = 3e-60 Identities = 139/318 (43%), Positives = 161/318 (50%), Gaps = 28/318 (8%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G AG PG G G G KGEPG++G GA G PG +G G G G G++GE+G G P Sbjct: 870 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRR 411 +G G+ G G G GPPGP G G TGP G P GS G GPPG++G G + Sbjct: 930 GPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGS---PGADGPPGRDGAAGVK 986 Query: 412 GKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDKGETGLPGF 469 G G G G PG PGPPG G G K D EAG G G G G G Sbjct: 987 GDRGETGAVGAPGAPGPPGSPGPAGPTG-------KQGDRGEAGAQGPMGPSGPAGARGI 1039 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGS 529 G GP+G KGE GEP GE+G +G G G QG+ G PG G G G G G +G Sbjct: 1040 QGPQGPRGDKGEAGEP---GERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1096 Query: 530 AGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGE 589 G +GP G G G+PG G PG +G GE G GPPG PGP G GPPG Sbjct: 1097 PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP----AGPPGNPGPPGPPGPPG------ 1146 Query: 590 PGLDGNPGA---PGPRGP 604 PG+D + A P +GP Sbjct: 1147 PGIDMSAFAGLGPREKGP 1164 Score = 108 bits (269), Expect = 4e-23 Identities = 67/182 (36%), Positives = 80/182 (43%), Gaps = 41/182 (22%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQK---GEQGFEGSKGETGEKGEQGEK 348 G G+ G G G KG GEPGE GL G GF G + G G G +G +G G G + Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQR 408 G P G +G++G G GP GPPGP+G G+TGP GPP PG Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG----------------- 1137 Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND-------EHEAGGLKGDK 461 PPGPPGPPG GI + KG D + AGGL+ Sbjct: 1138 -------------PPGPPGPPG-PGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHD 1183 Query: 462 GE 463 E Sbjct: 1184 AE 1185 Score = 67.4 bits (163), Expect = 7e-11 Identities = 41/107 (38%), Positives = 51/107 (47%), Gaps = 11/107 (10%) Query: 1026 VLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPG-------PPGDPGPQGYRG 1078 ++R+ + V L+ L Q +PGP G+ G PG P G PGPQG G Sbjct: 1 MIRLGAPQTLVLLTLLVAAVLRCQGQDVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAG 60 Query: 1079 QKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 ++G RG+ G G G PG G G PG PG GPPGP G P Sbjct: 61 EQGPRGDRGD--KGEKGAPGPR--GRDGEPGTPGNPGPPGPPGPPGP 103 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 614 bits (1583), Expect = e-175 Identities = 384/930 (41%), Positives = 465/930 (50%), Gaps = 113/930 (12%) Query: 291 KGEAGLPGAPGSPGQKGHKGE---------PGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 KG+ G G PG PG+KG +G+ PGE+G GA G PG G+ G G +G G Sbjct: 547 KGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGP 606 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKG------------------DTGP 383 +G G G P + G++G G KG++GP G PGP G++G + GP Sbjct: 607 RGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP 666 Query: 384 PGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 PG P +PG G GP G PG EG G +G GPPG GPPG PGP G++G Sbjct: 667 PGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKG---------T 717 Query: 444 KDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQ 503 N+G G KG+KGE G PGF G VG KG +G+PG P +GE G G G G Sbjct: 718 SGNRGLQ-----GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQA 772 Query: 504 GVKGEPGDPGPPGLIGSPGLKG---QQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEK 560 G +G PG G G +G PGL G + G GS+G GP G +G G+ G G+ G++GE+ Sbjct: 773 GEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGER 832 Query: 561 GDPG-----GIIGPPGLPGPKGEAGPPGK-SLPGE---PGLDGNPGAPGPRGPKGERGLP 611 G PG G G G PGPKG+ G G +PGE PGL G PG PGP+GP G +G Sbjct: 833 GPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKD 892 Query: 612 GVHGSPGDIGPQGI----GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRD 667 G G PG G G G PG G GP G+ G GP G G PG PG PG G+PG + Sbjct: 893 GRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLE 952 Query: 668 GKPGLPGPPGDPIALPLLGDIGALLKNFCG-NCQASVPGLKSNKGEEGGAGEPGKYDSMA 726 G+ G G G P L G G L+ F G PG KG++G G G S Sbjct: 953 GREGAKGELGPPGPLGKEGPAG--LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010 Query: 727 RKGDIGPRGPPGIPGR---EGP------KGSKGERGYPGIPGEKGDEGLQGIPGIPGAPG 777 +G +GP G G+PG+ EGP KGS+GERG PG G+ G G G G PGA G Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070 Query: 778 PTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG------PPGPPGIPFNE-RNGMSSLYK 830 P+G G G G PG G+KG+KG GPPG+PG PGPPG + R G L+ Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFG 1130 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGP------PG 884 KG V + G GPPG +G PGP GE G +G G G G G RGP GP PG Sbjct: 1131 QKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPG 1190 Query: 885 IAGMSGKPGA------------PGPPGVPGEPGERGPVGDIGFPGPEG---PSGKPGING 929 + G G+PGA PGPPG PG PG +G +G+ G GP G P GK G G Sbjct: 1191 LPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPG 1250 Query: 930 KDGIPGAQGIMGKPGDRGPKGERGDQGI---PGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 +DG G+ G G PGD GP G+ G GI PG++G G+ G PG G G G GPPG Sbjct: 1251 EDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPG 1310 Query: 987 NKGSMGSPGHQGPPGSPGIPGIPA-DAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPA 1045 +G G G +G G G G P D R+ E + + P Sbjct: 1311 KRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPG 1370 Query: 1046 AMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGL 1104 + A G PGP G GLPG GD GP KGE+G G IGL G PG G Sbjct: 1371 LLGAPGQMGPPGPLGPSGLPGLKGDTGP------KGEKGHIGLIGLIGPPGEAGEK---- 1420 Query: 1105 PGSPGAPGPQGPPGPSGRCNPEDCLYPVSH 1134 G G PG QGPPGP G P + + H Sbjct: 1421 -GDQGLPGVQGPPGPKGDPGPPGPIGSLGH 1449 Score = 609 bits (1570), Expect = e-174 Identities = 363/857 (42%), Positives = 425/857 (49%), Gaps = 92/857 (10%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G G GA G PG G KG+ G +GL G PG GQ+G+ G G G GE GE+G +G P Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRR 411 G GE G +G LGP G PGP G G TG G P G++G G GPPG++G G + Sbjct: 590 GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQ 649 Query: 412 GKTGP------PGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETG 465 G GP PG+ GPPG PG PG+ G LG ++ G G +G G G Sbjct: 650 GLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK-----GAQGPPGSAG 704 Query: 466 LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKG 525 PG+PG G KG G G KGEKG+ G PG G G+KG+ G PG PG G G +G Sbjct: 705 PPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG 764 Query: 526 QQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKS 585 +G AG G GPPG G G+ G+PG G G G P G IG PG GP GE G GK+ Sbjct: 765 PKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPG-PKGSIGFPGPLGPIGEKGKSGKT 823 Query: 586 LPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGP 645 G+PGL+G G PG RG +G+ G G G GD+G G PGI G Sbjct: 824 --GQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGA--------------PGIPGE 867 Query: 646 RGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPG 705 +GLPGL G PG PG G PG GK G PG PG G++G F G Q PG Sbjct: 868 KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQR------GELG-----FQG--QTGPPG 914 Query: 706 LKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEG 765 G +G GE G G GP G G+PG EG +G+KGE G PG G++G G Sbjct: 915 PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974 Query: 766 LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE---- 821 L+G PG G PG GP GL G G PGP GA G G GP G G G PG +E Sbjct: 975 LRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVG 1034 Query: 822 ---RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG 878 + G G PGP GP GP G GP GE G G G G G KGD+G Sbjct: 1035 PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKG 1094 Query: 879 PAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQG 938 AGPPG G+ G G PGPPG G G RGP G G G +G G G+ G G+ G G Sbjct: 1095 DAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPG 1154 Query: 939 IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQG 998 G+ G+ G G G G PG RG QG G G G+ G +G G G KG G G G Sbjct: 1155 PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPG 1214 Query: 999 PPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP 1058 PPG+PGIPG D + + AA G+ GP Sbjct: 1215 PPGAPGIPGPKGD--------------------------IGEKGDSGPSGAAGPPGKKGP 1248 Query: 1059 PGKD---------GLP---GPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLP 1105 PG+D GLP GPPGDPG G G GE+G+PG +G PG PG A G P Sbjct: 1249 PGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPG-----ASGEP 1303 Query: 1106 GSPGAPGPQGPPGPSGR 1122 G+PG PG +GP G GR Sbjct: 1304 GAPGPPGKRGPSGHMGR 1320 Score = 565 bits (1455), Expect = e-160 Identities = 364/902 (40%), Positives = 421/902 (46%), Gaps = 167/902 (18%) Query: 300 PGSPGQKGHKGEPG--ENG--LHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAG 355 PG+ G+KG KGEP E G G PG PG +G G G G G G+ G G L G Sbjct: 370 PGA-GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPG 428 Query: 356 LNGENGLKGDLGP-------------HGPP--------------------GPKGEKGDTG 382 + G +G++G G GPP GP G G TG Sbjct: 429 IPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTG 488 Query: 383 PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYY 442 PGP LPG G++G +G G +G RG +G GPPG+ G G PG G +G+ G Sbjct: 489 RPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGP-- 546 Query: 443 NKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS 502 K ++G D GL G+KG+ G G G GP G+ GE G G G GEPG G Sbjct: 547 -KGDRGFDG--LPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGL 603 Query: 503 QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI---KGE 559 G +G PG G PG+ G G G +G+ G G GPPG G G G+PG QG+ GE Sbjct: 604 LGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGE 663 Query: 560 KGDPGGIIGPPGLPGPKGEAGPPG-------KSLPGEPGLDGNPGAPGPRGPKGERGLPG 612 KG PG G PGLPG G G PG K G PG G PG PGPRG KG G G Sbjct: 664 KGPPGNP-GIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRG 722 Query: 613 VHGSPGDIGPQGI----------GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDG 662 + G G+ G G G G+ GA GP GE G +GP+G G G G PG+ G Sbjct: 723 LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAG 782 Query: 663 VPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKY 722 G+ G PGLPG PG P +G G L G KG+ G G+PG Sbjct: 783 EKGKLGVPGLPGYPGRPGPKGSIGFPGPL-------------GPIGEKGKSGKTGQPGLE 829 Query: 723 DSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPP 782 G G RG PG G+ GPKG G+ G PGIPGEKG GLQG PG PG GP G Sbjct: 830 GERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQ 889 Query: 783 GLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 G GR GHPG G G +G GPPG G GP G G Sbjct: 890 GKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQG-----------------------KTG 926 Query: 843 PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPG 902 GP G +G PGP G PG GLPGLEG G KG+ GP GP G G +G G PGP G PG Sbjct: 927 EVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPG 986 Query: 903 EPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP------KGERGDQG 956 +PG G GD G PGP G +G PG G G G G+ G+ G GP KG RG++G Sbjct: 987 DPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERG 1046 Query: 957 IPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ---------GPPGSPGIPG 1007 PG G G G G G GA GP G G+KG +G+PGH+ GPPG PGI G Sbjct: 1047 PPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRG 1106 Query: 1008 IPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP 1067 PA G PGPPG DG G Sbjct: 1107 -PA-------------------------------------------GHPGPPGADGAQGR 1122 Query: 1068 PGDPGPQGYRGQKGERGEPG-IGLPGSPGLPG-------TSALGLPGSPGAPGPQGPPGP 1119 G PG G +G G RG G IG PG GLPG +G G GAPGP+GP GP Sbjct: 1123 RGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGP 1182 Query: 1120 SG 1121 +G Sbjct: 1183 TG 1184 Score = 541 bits (1393), Expect = e-153 Identities = 410/1249 (32%), Positives = 517/1249 (41%), Gaps = 253/1249 (20%) Query: 71 ESDKTCFKLGSALLIR-DTIKIFPKG-LPEEYSVAAMFRVRRNAKKERWFLWQVLNQQNI 128 E D+ F++G A + T ++FP+G PE +S+ R + L + +++ Sbjct: 60 EGDRA-FRIGQASTLGIPTWELFPEGHFPENFSLLITLR---GQPANQSVLLSIYDERGA 115 Query: 129 PQISIVVDGGKKVVEFMFQATEGDVLNYIFRNRELRPLFDRQWHKLGISIQSQVISLYMD 188 Q+ + + ++ F+ V L D +WH++ +SI ++++L D Sbjct: 116 RQLGLALGPALGLLGDPFRPLPQQV-----------NLTDGRWHRVAVSIDGEMVTLVAD 164 Query: 189 CNLIARRQTDEKDTVDFHGRTVIATRASDGKPVDIELHQLKI---------YCSA----- 234 C + G TV+ T+ K + ++ +L I C Sbjct: 165 CEAQPPVLGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPDC 224 Query: 235 -NLIAQETCCEISDTKCP----EQDGFGNIASSWVTAHASKMSSYL----PAKQELKDQC 285 NL T + + P + G G K + + P ++Q Sbjct: 225 DNLAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQT 284 Query: 286 QCIPNKGEAGLPGAPGSPG--------QKGHKGEPGENGLHGAPGF--------PGQKGE 329 K E P P +P G E L G ++ E Sbjct: 285 STDIPKTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDE 344 Query: 330 QGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGD----------------LGPHG--- 370 +G + + G E + + GE G KG+ GP G Sbjct: 345 EGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG 404 Query: 371 ---PPGPKGEKGDTGPPGPPALPGSLGIQGPQGPP------------------------- 402 PPGP G GD GPPGP LPG GI G +GPP Sbjct: 405 PSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA 464 Query: 403 --------------GKEGQRGRRGKTGPPGKPGPP---------GPPGPPGIQGIHQTLG 439 G G G G+ GP G PG P GP GP G+QG H G Sbjct: 465 QAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG 524 Query: 440 GYYNKDNKGNDEHEA----GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRG 495 G D G KGD+G GLPG PG G +G G G+P GE G+RG Sbjct: 525 RVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERG 584 Query: 496 EPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQG 555 G G G GEPG G G GSPG G+ G G G G G+VG PGE G PG+QG Sbjct: 585 AEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQG 644 Query: 556 IKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGV 613 G +G PG G+IG PG GP G G PG LPG G G+PG GP G KG +G PG Sbjct: 645 NHGSQGLPGPQGLIGTPGEKGPPGNPGIPG--LPGSDGPLGHPGHEGPTGEKGAQGPPGS 702 Query: 614 HGSPGDIGPQGI-------------------------------GIPGRTGAQGPAGEPGI 642 G PG GP+G+ G G+ GA GP GE G Sbjct: 703 AGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGP 762 Query: 643 QGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702 +GP+G G G G PG+ G G+ G PGLPG PG P +G G L Sbjct: 763 EGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPL----------- 811 Query: 703 VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKG 762 G KG+ G G+PG G G RG PG G+ GPKG G+ G PGIPGEKG Sbjct: 812 --GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKG 869 Query: 763 DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP---------------- 806 GLQG PG PG GP G G GR GHPG G G +G GPP Sbjct: 870 LPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG 929 Query: 807 --GKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGL 864 G+ GPPGPPG P G L ++G GPPGP G +G G G PG G Sbjct: 930 PLGERGPPGPPGPP-----GEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGG 984 Query: 865 PGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPP---GVPGEPGERGPVGDIGFPGPEGP 921 PG G G+KGD+GP GP G G G+ G GP G+PG+ G GPVG G G G Sbjct: 985 PGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGE 1044 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQ---GIPGDRGSQGERGKPGLTGMKGA 978 G PG GKDGIPG G +G PG GP GE GD+ G PG +GS+G++G G G G Sbjct: 1045 RGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI 1104 Query: 979 IGPMGPPGNKGSMGSPGHQGPP------------------GSPGIPGIPADAVSFEEIKK 1020 GP G PG G+ G+ G +GPP G PG+ G+P E+ Sbjct: 1105 RGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEV-- 1162 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 + A G GP G +G PG PG G G G+K Sbjct: 1163 ------------------GDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEK 1204 Query: 1081 GERGEPG-IGLPGSPGLPGTSA-------LGLPGSPGAPGPQGPPGPSG 1121 GERG+ G G PG+PG+PG G G+ G PG +GPPG G Sbjct: 1205 GERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDG 1253 Score = 439 bits (1128), Expect = e-123 Identities = 293/723 (40%), Positives = 341/723 (47%), Gaps = 126/723 (17%) Query: 489 GEKGDRGEPGVIGS-QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGE 547 GEKG +GEP VI Q +G PG PGP G++G +G GP G PGD G PG Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGP---------SGPPGPPGFPGDPGPPGP 423 Query: 548 HGIPGKQGIKGEKGDPGGII------------GPP--------------------GLPGP 575 G+PG GI G +G PG +I GPP G PGP Sbjct: 424 AGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGP 483 Query: 576 KGEAGPPGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQ 634 G G PG LPG PGL G GA GP+GP RGL G HG PG +G +G PG GA+ Sbjct: 484 VGLTGRPGPVGLPGHPGLKGEEGAEGPQGP---RGLQGPHGPPGRVGK--MGRPGADGAR 538 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKN 694 G G+ G +G RG GLPG PG G G G G+PG PG G+ A G G Sbjct: 539 GLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG----- 593 Query: 695 FCGNCQASVPG---LKSNKGEEGGAGEPGKYD---SMARKGDIGPRGPPGIPGREGPKGS 748 QA PG L +G G G PG + KG++GP G PG PG++G GS Sbjct: 594 -----QAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648 Query: 749 KGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGK 808 +G G G+ G G++G G PGIPG PG GP +G GH GPTG KG +G G G Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGP---LGHPGHEGPTGEKGAQGPPGSAGP 705 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLE 868 PG PGP G+ +G L KG +PG G G KGD G G PG G G E Sbjct: 706 PGYPGPRGV--KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPE 763 Query: 869 GFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGIN 928 G G G G GPPG AG GK G PG PG PG PG P G IGFPGP GP G+ G + Sbjct: 764 GPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPG---PKGSIGFPGPLGPIGEKGKS 820 Query: 929 GKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988 GK G PG +G G PG RG +G+ G G PG +G G+ G PG+ G KG G GPPG Sbjct: 821 GKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP 880 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G G PGHQG G PG PG + + F+ + PA +L Sbjct: 881 GPKGPPGHQGKDGRPGHPGQRGE-LGFQG--------------------QTGPPGPAGVL 919 Query: 1049 AAQAY-------------GRPGPPGKDGLPG---------------PPGDPGPQGYRGQK 1080 Q G PGPPG+ GLPG P G GP G RG Sbjct: 920 GPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFP 979 Query: 1081 GERGEPG----IGLPGSPGLPG-TSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHA 1135 G +G PG GL G G PG A G PG G GP G G G+ E + P Sbjct: 980 GPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKK 1039 Query: 1136 HQR 1138 R Sbjct: 1040 GSR 1042 Score = 322 bits (825), Expect = 1e-87 Identities = 197/484 (40%), Positives = 238/484 (49%), Gaps = 48/484 (9%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KG+ G PG GS G KG G PG+ G+ G G PG G G +G +G G G++G+ G Sbjct: 1077 DKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDG 1136 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGP---QGPPGKEG 406 G+ G GL+G GPPG KGE GD G GP PG G QGP +G PG G Sbjct: 1137 VRGFVGVIGPPGLQG---LPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG 1193 Query: 407 QRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL 466 G+ G G G+ G G PGPPG GI G G KGD G +G Sbjct: 1194 GVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDI--------------GEKGDSGPSGA 1239 Query: 467 PGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQ 526 G PG GP G+ G G G GD G PG G G+ G PG+ G PG +G P G Sbjct: 1240 AGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGP---GP 1296 Query: 527 QGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSL 586 G++G G GPPG G G G G++G KG KG+PG GPPG GP G GPPG+ Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGP-DGPPGRTGPMGARGPPGR-- 1353 Query: 587 PGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPR 646 G +G G PGP G G G PG G PG +GP G+PG G GP GE G G Sbjct: 1354 ---VGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPS--GLPGLKGDTGPKGEKGHIGLI 1408 Query: 647 GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGL 706 GL G PG G G+ G+PG G PG G PG P + LG G PG+ Sbjct: 1409 GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP-------------PGV 1455 Query: 707 KSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGP-KGSKGERGYPGIPGEKGDEG 765 G++G G PG SM +GD GP GPPG PG G + R + +P + G Sbjct: 1456 AGPLGQKGSKGSPG---SMGPRGDTGPAGPPGPPGAPAELHGLRRRRRFVPVPLPVVEGG 1512 Query: 766 LQGI 769 L+ + Sbjct: 1513 LEEV 1516 Score = 216 bits (549), Expect = 1e-55 Identities = 153/410 (37%), Positives = 175/410 (42%), Gaps = 121/410 (29%) Query: 792 GPTGAKGE-----KGS--DGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPP 844 G GAKGE KG +GPPG PGP G G PS GPP Sbjct: 373 GEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG---------------------PS--GPP 409 Query: 845 GPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGD-------------RGPA----------- 880 GPPG GDPGP G G G+PG++G G G +GP Sbjct: 410 GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469 Query: 881 ---------GPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKD 931 GPPG G++G+PG G PG PG GE G G G G +GP G PG GK Sbjct: 470 LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529 Query: 932 GIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGK---------PGLTGMKGAIGPM 982 G PGA G G PGD GPKG+RG G+PG G +G+RG PG G +GA GP Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589 Query: 983 GP------PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAV 1036 GP PG +G +G G GP G PG+ GI Sbjct: 590 GPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDG-------------------------- 623 Query: 1037 FLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGL 1096 P A G PGPPG+ G G G PGPQG G GE+G PG PG PGL Sbjct: 624 ------APGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGN--PGIPGL 675 Query: 1097 PGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCL----YPVSHAHQRTGGN 1142 PG+ G G PG +GP G G P YP + T GN Sbjct: 676 PGSD-----GPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGN 720 Score = 38.1 bits (87), Expect = 0.048 Identities = 20/44 (45%), Positives = 21/44 (47%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQG 331 I + G G PG G GQKG KG PG G G G G G G Sbjct: 1444 IGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 612 bits (1579), Expect = e-175 Identities = 395/946 (41%), Positives = 458/946 (48%), Gaps = 164/946 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE-KGEQGEKGD 350 G G+PG G+ G KG G PG GL G PGFPG +G+ G +G KGET + +G+ G GD Sbjct: 496 GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 351 PALAGLNGENGLKG---DLGPHGPPGPKGE------KGDTGPPGPPALPGSLGIQGPQGP 401 P L G G GL G G G PGPKGE KGD GPPG P PGS G GP GP Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615 Query: 402 PGK--------EGQRGRRGKTGPPGK-------------PGPPGPPGPPGIQGIHQTLGG 440 PG +G +G G GPPG+ PGPPGPPGPPG G Q G Sbjct: 616 PGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG-PQGPPG 674 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPG--FPGSVGPKGQKGEPGEPFTKGEKGDRGEPG 498 K D GL G GE G+PG FPG GPKG +G PG + G G GEPG Sbjct: 675 IPGSLGKCGDP----GLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 499 VIGSQGVKGEPGDPGP--PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G+ G G+P PG G+PG G++G++G G G PG LPG G PG +G+ Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG---LPGLPGTPGNEGL 787 Query: 557 KGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGS 616 G +GDPG PGP GE GPPG+ + G G G PG G +G +G RG G G Sbjct: 788 DGPRGDPGQ-------PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 617 PGDIGPQGIGIPGRTGAQGPAGEPGIQGP---RGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 PG G G PG TG+ G G G GP RG PG PG G PG DGV G G PG Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GPPG P G G+ +PG+K +G G GE G KG+ GP Sbjct: 901 GPPGPPGNPGTPGQRGS----------PGIPGVKGQRGTPGAKGEQGD------KGNPGP 944 Query: 734 ---------RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 +G PG+ G G G KG RG PG+PG KG L+G+PG G PGP G G Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKG---LKGLPGPAGPPGPRGDLGS 1001 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNVPSYPGP 843 G G PG G G G+ G PG G G G P R G+ ++ ++G P Y Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061 Query: 844 --PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PGPPGP GDPG PG MG G G PG G GPAGP G G G PG PG PG Sbjct: 1062 TRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 902 GE------------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD-RGP 948 G+ PG RGP G GFPG GP G G G+DGIPG G G+ G R P Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 949 KGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP--------------------PGNK 988 G RG+ G G +G +G G PGL G KGA+G GP PG Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G+ G PG +G PG+PG PG P V+ I ++ ++ K P Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGS-------------HVIGIKGDKGSMGHPGPKGPPGTA 1285 Query: 1049 AAQAY-GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-------------------- 1087 GR G PG GLPGP GDPG QG+ G KGE+G PG Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1088 --------IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 I LPGSPG PGT G PG G PGP GPPG G C P Sbjct: 1346 GDPGTLKIISLPGSPGPPGTP--GEPGMQGEPGPPGPPGNLGPCGP 1389 Score = 586 bits (1510), Expect = e-167 Identities = 398/991 (40%), Positives = 461/991 (46%), Gaps = 183/991 (18%) Query: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLH--GAPGFPGQKGEQGFEGSKGETGEKGE-Q 345 P GL GAPG PG KG KGE G G G PG PG G G GS G G G+ Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP--------PGPPALPGSLGIQG 397 KG P G++GL G LG G PG G KG+ G PGPP LPG G+ G Sbjct: 443 FRKGPP------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Query: 398 PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 +G PG++G G +G G PG G PG PG PG QG G K E + G Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG---EKGETLQPEGQVGVP 553 Query: 456 ---GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP 512 GL+G G GL G PG+ G KG G GE GEKGD+G PG GS G G G Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613 Query: 513 GPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG-------LPGEHGIPGKQGIKGEKGDP 563 GPPG G PGL+G QG G+ GP G G G +PG G PG G G +G P Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 564 G-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP------KGERGLPG 612 G G G PGLPGP GE G PG PG PG G+ G PG +G GE GLPG Sbjct: 674 GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG---LPGLPGTPGTPGNDGVPGRDGK 669 G PG G + +PG G G GE G G G LPGLPG PGTPGN+G+ G G Sbjct: 734 KPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGD 793 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK-----YDS 724 PG PGPPG+ G G ++ G +PGL KG++G G+ G Sbjct: 794 PGQPGPPGEQ------GPPGRCIEGPRG--AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGP 778 + R G G G PGIPG +G G G+RGYPG PG E G G+ G PG G PGP Sbjct: 846 LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905 Query: 779 TGPPGLMGRTGHPGPTGAKGE------KGSDGPPGKPGPP---------GPPGI------ 817 G PG G+ G PG G KG+ KG G G PGP G PG+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 818 PFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG---- 869 P + N GM L +KG PGP GPPGP+GD G G PG GL G+ G Sbjct: 966 PGEKGNRGVPGMPGLKGLKG------LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGN 1019 Query: 870 --FPGVKGDRGPAGPPGIAGMSG--------------------KPGAPGPPGVPGEPGER 907 PG KG RG G PG AG G +PG PGP G PG PG+ Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079 Query: 908 GPVGDIGFPGPEG------PSGKPGINGKDGIPGA------------QGIMGKPGDRGPK 949 G G++G PGP G P G PG G G+PG +G++G PG RGP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 950 GERGDQGIPGD---RGSQGERGKPGLTGMKGAIG----PMGPPGNKGSMGSPGHQGPPGS 1002 G G G PG RG QG G PG G KG G P GP GN G+ G+ G +G PG Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKD 1062 PG+PG +K + + F LP A++ Q G GPPG Sbjct: 1200 PGLPG-----------RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSR 1247 Query: 1063 GLPGPPGDPGPQG-----YRGQKGERGEPG----------------IGLPGSPGLPGTSA 1101 G PG PG PGP G +G KG G PG +G PG+PGLPG Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG 1307 Query: 1102 -LGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 G G PG G +G PG G P + P Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP 1338 Score = 585 bits (1509), Expect = e-167 Identities = 396/992 (39%), Positives = 471/992 (47%), Gaps = 192/992 (19%) Query: 291 KGEAGLPGAPG---SPGQKGHKGEPG--------ENGLHGAPGFPGQKGEQGFEGSKGE- 338 KG+ G PG PG + G +G G PG GL GAPG+PG KG +G G G+ Sbjct: 353 KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412 Query: 339 -TGEKGEQGEKGDPALAGL----------------NGENGLKGDLGPHGPPGPKGEKGDT 381 G G G G P L G G++GL G LG G PG G KG+ Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 382 G--------PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G PGPP LPG G+ G +G PG++G G +G G PG G PG PG PG QG Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532 Query: 434 IHQTLGGYYNKDNKGNDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTK 488 G K E + G GL+G G GL G PG+ G KG G GE Sbjct: 533 DPGLKG---EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 489 GEKGDRGEPGVIGSQGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG--- 543 GEKGD+G PG GS G G G GPPG G PGL+G QG G+ GP G G G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELS 649 Query: 544 ----LPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDG 594 +PG G PG G G +G PG G G PGLPGP GE G PG PG PG G Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 595 NPGAPGPR------GPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPR-- 646 + G PG + G GE GLPG G PG G + +PG G G GE G G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 647 -GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPG 705 GLPGLPG PGTPGN+G+ G G PG PGPPG+ G G ++ G +PG Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ------GPPGRCIEGPRG--AQGLPG 821 Query: 706 LKSNKGEEGGAGEPGK-----YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP-- 758 L KG++G G+ G + R G G G PGIPG +G G G+RGYPG P Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 759 -GEKGDEGLQGIPGIPGAPGPTGP---------------PGLMGRTGHPGPTGAKGEKGS 802 G G++G+ G+ G PGA GP GP PG+ G+ G PG G +G+KG+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 803 DGP---------PGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGP 849 GP G+PG G G P + N GM L +KG PGP GPPGP Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG------LPGPAGPPGP 995 Query: 850 KGDPGPVGEPGAMGLPGLE------GFPGVKGDRGPAGPPGIAGMSG------------- 890 +GD G G PG GL G+ G PG KG RG G PG AG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 891 -------KPGAPGPPGVPGEPGERGPVGDIGFP------GPEGPSGKPGINGKDGIP--- 934 +PG PGP G PG PG+ G G++G P GP GP G PG G G+P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 935 ---------GAQGIMGKPGDRGPKGERGDQGIPGD---RGSQGERGKPGLTGMKGAIG-- 980 G +G++G PG RGP G G G PG RG QG G PG G KG G Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 981 --PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFL 1038 P GP GN G+ G+ G +G PG PG+PG +K + + F Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPTGIEGFP 1224 Query: 1039 SQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYR--GQKGERGEPGIGLPGSPGL 1096 LP A++ Q G GPPG G PG PG PGP G G KG++G +G PG G Sbjct: 1225 GPPGLPGAIIPGQT-GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--SMGHPGPKGP 1281 Query: 1097 PGTSA-------LGLPGSPGAPGPQGPPGPSG 1121 PGT+ LG PG+PG PGP+G PG G Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Score = 585 bits (1508), Expect = e-167 Identities = 395/964 (40%), Positives = 465/964 (48%), Gaps = 192/964 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG------EKGE 344 +G +GLPG GSPG G G G GL G PG G KGEQGF G G G G Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 345 QGEKGDPALA-----GLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQ 399 +G+KG PA G+ GL G GP G PGP G G GPPGPP G G GP+ Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 400 GPPGKEGQR--GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 GP G G+R G +G+ G G GPPGPPG + TL G N+ + ++ + G Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGT-----VIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 456 ---------GLKGDK--GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 GL G+ E G PG PG G G+ G PG P ++G KG+RG PG++G G Sbjct: 268 GEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 505 VKGEPGDPGPPGLIG---------------SPGLKGQQGSAGSMGPRGPPGDVGLPGEH- 548 +KG+ GD GPPG G +PG G +G+ G GP GPPG G PG Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387 Query: 549 -------GIPGKQGIKGEKGDPG----------GIIGPPGLPGPKGEAGPPG-----KSL 586 G PG +G KGE+G PG G G PGLPG G GPPG K Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447 Query: 587 PGE---PGLDGNPGAPGPRGPKGERGL--------PGVHGSPGDIGPQGI-GIPGRTGAQ 634 PG+ PG G+PG PG GPKGE GL PG G PG G G+ GIPGR GA Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP----GLPGPPGDPIALPLLGDIGA 690 G G PG G GLPG PG PG G+ G+ G G+ G G PGDP L G G Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP---GLRGQPG- 563 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 + + G+ G +G G G+ KGD GP G PG PG GP G G Sbjct: 564 ---------RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG-LMGRTGHPGPTGAKGEKGSDGPPGKP 809 GY G GE G +G QG+PG PG PG GP G L T PGP G G PPG P Sbjct: 615 PPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG------PPGHP 667 Query: 810 GPPGPPGIPFN-ERNGMSSLYKIKGGVNVPS--YPGPPGPPGPKGDPGPVGE---PGAMG 863 GP GPPGIP + + G L G +P +PGPPGP G +G PG G PG MG Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 864 LPGLEGFPGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGE 906 PGL G PG+ G +G P GP PG G SG+ PG PG PG PG G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 907 RGPVGDIGFPGPEGPSGKPGI-----NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-D 960 GP GD G PGP G G PG G G+PG G+ G+ G RG G +GD GIPG D Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 961 R-GSQGERGKPGLTGMKGAIGPMGP---PGNKGSMGSPGHQG------------PPGSPG 1004 R G GE G PG+ G +G +GP+G PGN G +G PG G PPG PG Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 1005 IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 PG P +R + + +K G+ G PG G Sbjct: 908 NPGTPG---------------------QRGSPGIPGVK-----------GQRGTPGAKGE 935 Query: 1065 PGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSP------GAPGPQGPP 1117 G G+PGP G++GEPG+ G G+PG G G+PG P G PGP GPP Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR--GVPGMPGLKGLKGLPGPAGPP 993 Query: 1118 GPSG 1121 GP G Sbjct: 994 GPRG 997 Score = 583 bits (1504), Expect = e-166 Identities = 413/1010 (40%), Positives = 469/1010 (46%), Gaps = 212/1010 (20%) Query: 282 KDQCQCIP---NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 K QC C KGE G PG PGSPGQKG G G G G GFPG G GSKG Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGL---PGLTGSKGV 92 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP---PALPGSLGI 395 G G G G P L G G G G +G G G KGE+G G PG P +PG+ G+ Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 396 QGPQGPPGKE--------------GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGY 441 +G +G P KE G G +G GPPG PGP GPPGPPG G +G Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 442 YNKDNKGNDEHEAGGLKGDKGETGLPGFPGSV-----------------GPKGQKGEPGE 484 K + G G +G KG TG PG PG+V G KG GEPG Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 485 PFTKG--------EKGDRGEPGVIGSQGVKGEPGDPGP---------PGLIGSPGLKGQQ 527 P G EKG G+PG+ G G G PG PG PGL+G G+KGQ+ Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Query: 528 GSAGSMGPRGP---------PGDVGLPGEHGIPGKQGIKGEKGDPG-------------G 565 G G G RGP GD G PG G G +G +G G PG G Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392 Query: 566 IIGPPGLPGPKGEAGPPGK---SLPGEPGLDGN---PGAPGPRGPKGE----RGLPGVHG 615 G PGL G KGE G PGK PG PG G+ PG+PGP GP G+ +G PG HG Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPGI---QGP--RGLPGLPGTPGTPGNDGVPGRDGKP 670 PG +G PG G GP GEPG+ Q P G PGLPG PG G G+PGR G Sbjct: 453 LPGYLGS-----PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 671 GLPGPPGDPIALPLLGDIGALLKNFCGNCQA-SVPGLKSNKGE----EGGAGEPGKYDSM 725 GL G PG P G+ G L F G A PGLK KGE EG G PG Sbjct: 508 GLKGSPGSP------GNTG--LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG---DP 556 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP---- 781 +G G +G GIPG G KG G +G + GEKGD+G G PG PG+PGP GP Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 782 -------PGLMGRTGHPGPTGAKGEKGSDGP-------PGKPGPPGPPGIPFNERNGMSS 827 PGL G G PG G GE G G PG PGPPGPPG P + G Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ--GPPG 674 Query: 828 LYKIKGGVNVPSYPGP-----------PGPPGPKGD------PGPVGEPGAMGLPGLEGF 870 + G P PGP PGPPGPKGD G +G PG MG PGL G Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 871 PGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGERGPVGDI 913 PG+ G +G P GP PG G SG+ PG PG PG PG G GP GD Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 914 GFPGPEGPSGKP-----GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-DR-GSQGE 966 G PGP G G P G G G+PG G+ G+ G RG G +GD GIPG DR G GE Sbjct: 795 GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854 Query: 967 RGKPGLTGMKGAIGP------------MGPPGNK---GSMGSPGHQGPPGSPGIPGIPAD 1011 G PG+ G +G +GP +GPPG G MG PG GPPG PG PG P Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 S + Q P A G PGP + G G+P Sbjct: 915 RGS-----------------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 1072 GPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G +G+ G GE+G G+ PG PGL G GLPG G PGP+G G +G Sbjct: 958 GLKGFAGNPGEKGNRGV--PGMPGLKGLK--GLPGPAGPPGPRGDLGSTG 1003 Score = 579 bits (1492), Expect = e-165 Identities = 390/958 (40%), Positives = 467/958 (48%), Gaps = 159/958 (16%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGEN--GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 KGE G GA G PG G G PGE+ GAPG PG +G+ G +G G G +G +G + Sbjct: 258 KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKG------EKGDTGPPGPPALPGSLGIQGPQGPP 402 G P L G +G G KGD+GP G GP EKGD G PGPP G+ G QGP GPP Sbjct: 318 GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377 Query: 403 GKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKG 462 G G G +PG G PG PG++G +K +G +A G G G Sbjct: 378 GVPGSPGS-------SRPGLRGAPGWPGLKG---------SKGERGRPGKDAMGTPGSPG 421 Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KGEPG------ 510 G PG PGS GP G G+ F KG GD G PG +GS G+ KGEPG Sbjct: 422 CAGSPGLPGSPGPPGPPGDI--VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQC 479 Query: 511 --DPGPPGLIGSPGLKG------QQGSAGSMGPRGPPGDVGLPGEHGIPGKQG---IKGE 559 PGPPGL G PGL G +QG+AG G G PG+ GLPG G PG QG +KGE Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGE 539 Query: 560 KGD---PGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGP---RGPKGERGLPG 612 KG+ P G +G PG PG +G+ G G +PG PG+ G PG G G KG++G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG-------------TPG 659 GSPG GP G P GP GEPG+QG +G+PG PG PG PG Sbjct: 600 DPGSPGSPGPAG---PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEP 719 G PG G PG GPPG P +L GD G L G G G +G G P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPG--LPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSK-----GERGYPGIPGEKGDEG------LQG 768 G S+ G +G G PG PG G KG G G PG PGE+G+ G L G Sbjct: 715 GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG 774 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE--------------------KGSDGPPGK 808 +PG+PG PG G G G G PGP G +G KG G GK Sbjct: 775 LPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG---DPGPVGEPGAMGLP 865 GP G PGIP +R+G G +P + G GP G +G +PG +G PG G+ Sbjct: 835 TGPKGDPGIPGLDRSGFPGE---TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891 Query: 866 GLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE------ 919 G+ GFPG G GP G PG G G PG PG G G PG +G GD G PGP Sbjct: 892 GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951 Query: 920 GPSGKPGINGKDGIPGAQG---IMGKPGDRGPKGERGDQGIPGDRG---SQGERGKPGLT 973 G G+PG+ G G PG +G + G PG +G KG G G PG RG S G G+PGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 974 GMKGAIGPMGPPGNKG---SMGSPGHQGPPGSPGIPGIPADA--VSFEEIKKY------- 1021 G+ G++G MG PG+KG ++G PG G PG PGI G+ D + E + Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 1022 ---INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG 1078 + ++ + E + Q P + A G PG PG GLPG PG G G++G Sbjct: 1072 DPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKG 1125 Query: 1079 QKGERGEPGI----GLPGSPGLPGTSAL-GLPGSPGAPGPQG----------PPGPSG 1121 KG G PGI GLPG PG PG + G G G PGP G PPGP G Sbjct: 1126 IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Score = 525 bits (1352), Expect = e-148 Identities = 335/811 (41%), Positives = 398/811 (49%), Gaps = 129/811 (15%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGF-----PGQKGEQGFEGSKGETGEKGEQG 346 G G PG PGS G+ G G PG +G G PG PG KG+QGF G+KG G G+ G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 347 EKGDPALAGLNGENGLKGDLGPHGP--PGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 E G P GL G G P GP PG GE+G++G G LPG G+ G G G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 405 EGQRGRRGKTGPPGKPGPPGP--PGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG----- 455 +G RG G+ GPPG+ GPPG GP G QG+ G G + K + + G Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE------PGVIGSQGVKG 507 G G+ G G+PG G +GP GQ+G PG P G G+ G PG IG G G Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG------------DVGLPGEHGIPGKQG 555 PG PG G G PG+KGQ+G+ G+ G +G G D G PG G G G Sbjct: 908 NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 556 IKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA------PGP 601 KG +G PG G+ GP G PGP+G+ G G PGEPGL G PG+ PG Sbjct: 968 EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN--PGEPGLRGIPGSMGNMGMPGS 1025 Query: 602 RGPKG---------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLP 652 +G +G GLPG+HG GD G G R G GP G+PG+ G G G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085 Query: 653 GTPGTPGN------DGVPGRDGKPGLPGPPGDPIALPLLGDIGAL----------LKNFC 696 G PG PG+ +G PG G PGLPG PG L G G L L F Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145 Query: 697 GNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG----PRGPPGIPGREGPKGSKGER 752 G+ PG +G++G G PG KG+ G P GP G PG +G KG +G Sbjct: 1146 GS-----PGPMGIRGDQGRDGIPGP---AGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP 1197 Query: 753 GYPGIPGEKG---DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKP 809 G+PG+PG KG D G +G GI G PGP G PG + PG TG +G GS G PG P Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAP 1253 Query: 810 GPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG 869 GPPGPPG S + IKG G PGP GP G G +G PG +G PG G Sbjct: 1254 GPPGPPG---------SHVIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 870 FPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGING 929 PG +GD PG G PGV GE G G +G IG PGP GP G PG+ G Sbjct: 1302 LPGPRGD---------------PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346 Query: 930 KDG------IPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMG 983 G +PG+ G G PG+ G +GE G G PG+ G G RGKPG G G GP G Sbjct: 1347 DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 984 PPGNKGSMGSPGHQGPPGSPGIPGIPADAVS 1014 GNKGS G PG G G PG+ G D+ S Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 516 bits (1328), Expect = e-146 Identities = 317/724 (43%), Positives = 372/724 (51%), Gaps = 81/724 (11%) Query: 295 GLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALA 354 G PG PG PG++G+ GE GE GL G PG PG G +G +G +G+ G+ G GE+G P Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 355 --------GLNGENGLKGDLGPHGPPGPKGEKG-----------DTGPPGPPA------- 388 GL G NGLKG G G GPKG+ G +TG PG P Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 389 -----LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGP------PGIQGIHQT 437 PG+ GI GP G G G G G GPPG PG PG PG PG++G T Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 438 LGGYYNKDNKGND-EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE 496 G + +KGN E + GDKGE GL GF G+ G KG +G PG P KG KG G Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 G G +G G G+PG PGL G PG G G GS G RG G G G G+PG G+ Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 557 KGEKGDPGGIIGP-PGLPGPKGEAGPPGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVH 614 +G+KG+PG G PG PGP G+ G PG GE G G PG GP GP+G G PG Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 615 GSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 G PG GP G +G G G GP PGI+GP PGLPG PG+PG G+ G G+ G+P Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGP---PGIRGP---PGLPGFPGSPGPMGIRGDQGRDGIP 1163 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GP G+ G+ G LL+ G PG + KG+ G G PG GD GP Sbjct: 1164 GPAGEK------GETG-LLRAPPG--PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL--------M 785 RGP GI G GP G G IPG+ G+ G G G PGAPGP GPPG Sbjct: 1215 RGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 786 GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKGGVNVPSYPG-- 842 G GHPGP G G G GPPG+ G PG PG+P + G +KG P + G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 843 -PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PPGP GPKG PG G+PG + + L G P GP G PG GM G+PG PGPPG Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSP------GPPGTPGEPGMQGEPGPPGPPGNL 1384 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 G G RG G G PG GP+G+ G G G PG G G P G KG+RGD G P Sbjct: 1385 GPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLP---GLKGKRGDSGSPATW 1441 Query: 962 GSQG 965 ++G Sbjct: 1442 TTRG 1445 Score = 465 bits (1197), Expect = e-131 Identities = 324/838 (38%), Positives = 373/838 (44%), Gaps = 194/838 (23%) Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG 468 G +G+ G G PGPPG PG KG TG G Sbjct: 43 GAKGEKGEKGFPGPPGSPG--------------------------------QKGFTGPEG 70 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 PG GPKG G PG +KG +G G PG GS G+ G PG+ GP GL+G PG G +G Sbjct: 71 LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE--------KGDPG--GIIGPPGLPGPKGE 578 G G G G G+PG G+ G++G + KGDPG G GP GLPGP G Sbjct: 131 EQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGF 190 Query: 579 AGPPGKSLPGEPGLDGNPGAPGPRGPKG-----------ERGLPGVHGSPGD-------- 619 GP G PG PG G PGA GPRGPKG ERG+ G+ G PG Sbjct: 191 PGPVGP--PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLP-----GTPGTPGNDGVPGRDGKPGLP 673 GP + G G +G GEPG GP GLPG G PG PG G PG+DG PG P Sbjct: 249 TGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 G G G +G + + G K + G G G YD+ KGD G Sbjct: 309 GSEGVKGNRGFPGLMG----------EDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 GPPG G GP+G G G PG PG GL+G PG PG G G G G+ G Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKDAM-GT 416 Query: 794 TGAKGEKGSDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG- 851 G+ G GS G PG PGPPGPPG I F R G + + G + P PG GP G G Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVF--RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 852 -------DPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEP 904 PGP G PG GL G++G PG +G G G PG G +G PG PG PG G+P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534 Query: 905 GERG-------PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP---KGERGD 954 G +G P G +G PG G G+PG G DGIPG G+ G PG +G GE+GD Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 955 QGIPGDRGSQGE--------------RGKPGLTGMKGAIGPMGPPGNKGSMGS------- 993 QG PGD GS G +G+PGL G +G G GPPG G G Sbjct: 595 QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 994 ---------PGHQGPPGSPGIPG------------------IPADAVSFEEIKKYINQEV 1026 PGH GP G PGIPG IP K Sbjct: 655 PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG----- 709 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP--------PGDPGPQGYRG 1078 ++ L P M G PG PGK GLPG PG PG G+ G Sbjct: 710 ----DQGFPGTKGSLGCPGKM------GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 1079 QKGERGEPG-IGLPGSPGLPGTSALGLPGSP------------GAPGPQGPPGPSGRC 1123 ++G GE G IGLPG PGLPGT P G PGP G GP GRC Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGT--------PGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 358 bits (919), Expect = 2e-98 Identities = 237/593 (39%), Positives = 274/593 (46%), Gaps = 96/593 (16%) Query: 291 KGEAGLPGAPG------------SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 KGE G G PG PG KG G PGE G G PG PG KG +G G G Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPP---GPPALPGSLGI 395 G +G+ G G+P GL G + G +G G PG KG++G G P G P LPG G+ Sbjct: 993 PGPRGDLGSTGNPGEPGLRG---IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 396 QGPQGPPG-KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA 454 QG +G PG EG R PGPPGP G PG+ G Sbjct: 1050 QGDKGEPGYSEGTR-----------PGPPGPTGDPGLPG--------------------D 1078 Query: 455 GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP 514 G KG+ G+ G PG G GP+G G PG P G+ G G+ G G +G+ G PG GP Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 515 PGLIGSP------GLKGQQGSAGSMGPRGPPGDVGL----PGEHGIPGKQGIKGEKGDPG 564 PGL G P G++G QG G GP G G+ GL PG G PG QG KG++G P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP- 1197 Query: 565 GIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGN--PGAPGPRGPKGERGLPGVHGSPG 618 G G PG G G+AGP G + PG PGL G PG G RGP G RG PG G PG Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257 Query: 619 DIGPQGIGIP------GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 G IGI G G +GP G G GP G G PGTPG PG G PG G PG+ Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGV 1317 Query: 673 PGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG 732 G G+P LG IG PG KG G G+PG ++ G Sbjct: 1318 KGEKGNP---GFLGSIGP-------------PGPIGPKGPPGVRGDPGTLKIISLPGS-- 1359 Query: 733 PRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPG 792 GPPG PG G +G G G PG G G G G G PG PGP G G G G PG Sbjct: 1360 -PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 793 PTGAKGEKGSDGPPGKPGPPG---PPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 P G+ G G G G G P G F + +++ G VP Y G Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG-TVPLYSG 1470 Score = 324 bits (831), Expect = 3e-88 Identities = 217/533 (40%), Positives = 250/533 (46%), Gaps = 105/533 (19%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEP---------------GENGLHGAPGFPGQKGEQGFEG 334 N GE G G PG PG KG KG P G G G G PG G G G Sbjct: 965 NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024 Query: 335 SKGETGEKGEQGEKGDPALAGLNGENGLKGD--------LGPHGP------PGPKGEKGD 380 SKG+ G G G G P L G++G G KG+ GP GP PG G+KG+ Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGP---------PGKPGPPGPPGPPGI 431 G PGP PG LG GP+G PG G G GK GP G GPPG GPPG+ Sbjct: 1085 MGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141 Query: 432 QGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL-------PGFPGSVGPKGQKGEPGE 484 G + G + ++G D G G+KGETGL G PG+ G KG +G PG Sbjct: 1142 PGFPGSPGPMGIRGDQGRD--GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 485 PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544 P G KG G+ G G G++G PG PG PG I PG G +G GS G G PG G Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPPGSRGSPGAPGPPGP 1258 Query: 545 PGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 PG H I GIKG+KG G GP G PG G+ GPPG+ G G PG PGPRG Sbjct: 1259 PGSHVI----GIKGDKGSMGH-PGPKGPPGTAGDMGPPGRL-----GAPGTPGLPGPRGD 1308 Query: 605 KGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGV 663 G +G PGV G G+ G G IG PG G +GP G G G + LPG+PG PG G Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Query: 664 PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 PG G+PG PGPPG N G G G+PGK Sbjct: 1369 PGMQGEPGPPGPPG-------------------------------NLGPCGPRGKPGK-- 1395 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP 776 G PG PG G KG+KG +G PG G G GL+G G G+P Sbjct: 1396 ----------DGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 266 bits (680), Expect = 8e-71 Identities = 173/413 (41%), Positives = 201/413 (48%), Gaps = 72/413 (17%) Query: 289 PNKGEAGLPGAPGS------PGQKGHKGE------------------PGENGLHGAPGFP 324 P E PG PG PG G KGE PG G G PG P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 325 GQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTG-- 382 G G+ GF+G KG G G +G G P G G G++GD G G PGP GEKG+TG Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 383 --PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP---PGPPGIQGIHQT 437 PPGP PG+ G +G +G PG G GR+G G G GP G PGPPG+ G Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AI 1233 Query: 438 LGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGS--VGPKGQKGEPGEPFTK---GEKG 492 + G N+G G +G G G PG PGS +G KG KG G P K G G Sbjct: 1234 IPG--QTGNRG-----PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 D G PG +G+ G G PG G PG G PG+KG++G+ G +G GPPG +G G G+ Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV-- 1344 Query: 553 KQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP---RGPKGE 607 +GDPG II PG PGP G PGEPG+ G PG PGP GP G Sbjct: 1345 -------RGDPGTLKIISLPGSPGPPG--------TPGEPGMQGEPGPPGPPGNLGPCGP 1389 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G PG GP G G +G GEPG G GLPGL G G G+ Sbjct: 1390 RGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 220 bits (560), Expect = 7e-57 Identities = 148/385 (38%), Positives = 175/385 (45%), Gaps = 90/385 (23%) Query: 780 GPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G G G G PGP G+ G+KG GP G PGP GP G P G++ ++G +P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP--GLPGLTGSKGVRGISGLPG 100 Query: 840 YPGPPGPPGPKGDPGP---VGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAP- 895 + G PG PG G+ GP VG PG G G +GFPG+ G G G PG AG+ G+ GAP Sbjct: 101 FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA 160 Query: 896 ----------GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD 945 G PG+PG PG +G G GFPGP GP G PG G PGA G Sbjct: 161 KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG---FPGAMG------P 211 Query: 946 RGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN--------------KGSM 991 RGPKG G++ I G +GERG GLTG P GPPG KG Sbjct: 212 RGPKGHMGERVI----GHKGERGVKGLTG------PPGPPGTVIVTLTGPDNRTDLKGEK 261 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G G G PG PG G+P ++ E+ A Sbjct: 262 GDKGAMGEPGPPGPSGLPGESYGSEKG------------------------------APG 291 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSAL----- 1102 G G PGKDG+PG PG G +G RG G GE GI G G PG G + Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 1103 --GLPGSPGAPGPQGPPGPSGRCNP 1125 G G+PG PGP+G GP G P Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGP 376 Score = 152 bits (384), Expect = 2e-36 Identities = 102/275 (37%), Positives = 121/275 (44%), Gaps = 61/275 (22%) Query: 876 DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKP---------G 926 D+G G G G+ G PGPPG PG+ G GP G PGP+GP G P G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPE---GLPGPQGPKGFPGLPGLTGSKG 91 Query: 927 INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 + G G+PG G G PG G G G G+PG GS+GE+G PGL G G G G G Sbjct: 92 VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 987 NKGSMGSPGHQ-----GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 KG G+P + G PG+PG P Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQ----------------------------- 182 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 LP G PGPPG G PG G GP+G+ G++ G +GE G+ GL G PG PG Sbjct: 183 GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Query: 1099 TSAL------------GLPGSPGAPGPQGPPGPSG 1121 T + G G GA G GPPGPSG Sbjct: 243 TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Score = 147 bits (372), Expect = 4e-35 Identities = 84/206 (40%), Positives = 96/206 (46%), Gaps = 35/206 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KG G PG G PG G G PG G G PG PG +G+ GF+G G GEKG G Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--- 1325 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPGSLGIQGPQGPPG 403 G G G +GP GPPG +G+ G G PGPP PG G+QG GPPG Sbjct: 1326 ------FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463 G G G G PGK G PG PGP G K NKG+ KG+ G Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGPAG------------EKGNKGS--------KGEPGP 1419 Query: 464 TGLPGFPGSVGPKGQKGEPGEPFTKG 489 G G PG G +G G P T+G Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 67.8 bits (164), Expect = 6e-11 Identities = 38/83 (45%), Positives = 44/83 (53%), Gaps = 8/83 (9%) Query: 1054 GRPGPPGKDGLPGPPGDPG------PQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLP 1105 G G G+ G PGPPG PG P+G G +G +G PG+ GL GS G+ G S L G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 1106 GSPGAPGPQGPPGPSGRCNPEDC 1128 GSPG PG G GP G C Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGC 125 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 612 bits (1579), Expect = e-175 Identities = 395/946 (41%), Positives = 458/946 (48%), Gaps = 164/946 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE-KGEQGEKGD 350 G G+PG G+ G KG G PG GL G PGFPG +G+ G +G KGET + +G+ G GD Sbjct: 496 GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 351 PALAGLNGENGLKG---DLGPHGPPGPKGE------KGDTGPPGPPALPGSLGIQGPQGP 401 P L G G GL G G G PGPKGE KGD GPPG P PGS G GP GP Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615 Query: 402 PGK--------EGQRGRRGKTGPPGK-------------PGPPGPPGPPGIQGIHQTLGG 440 PG +G +G G GPPG+ PGPPGPPGPPG G Q G Sbjct: 616 PGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG-PQGPPG 674 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPG--FPGSVGPKGQKGEPGEPFTKGEKGDRGEPG 498 K D GL G GE G+PG FPG GPKG +G PG + G G GEPG Sbjct: 675 IPGSLGKCGDP----GLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 499 VIGSQGVKGEPGDPGP--PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G+ G G+P PG G+PG G++G++G G G PG LPG G PG +G+ Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG---LPGLPGTPGNEGL 787 Query: 557 KGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGS 616 G +GDPG PGP GE GPPG+ + G G G PG G +G +G RG G G Sbjct: 788 DGPRGDPGQ-------PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 617 PGDIGPQGIGIPGRTGAQGPAGEPGIQGP---RGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 PG G G PG TG+ G G G GP RG PG PG G PG DGV G G PG Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GPPG P G G+ +PG+K +G G GE G KG+ GP Sbjct: 901 GPPGPPGNPGTPGQRGS----------PGIPGVKGQRGTPGAKGEQGD------KGNPGP 944 Query: 734 ---------RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 +G PG+ G G G KG RG PG+PG KG L+G+PG G PGP G G Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKG---LKGLPGPAGPPGPRGDLGS 1001 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNVPSYPGP 843 G G PG G G G+ G PG G G G P R G+ ++ ++G P Y Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061 Query: 844 --PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PGPPGP GDPG PG MG G G PG G GPAGP G G G PG PG PG Sbjct: 1062 TRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 902 GE------------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD-RGP 948 G+ PG RGP G GFPG GP G G G+DGIPG G G+ G R P Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 949 KGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP--------------------PGNK 988 G RG+ G G +G +G G PGL G KGA+G GP PG Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G+ G PG +G PG+PG PG P V+ I ++ ++ K P Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGS-------------HVIGIKGDKGSMGHPGPKGPPGTA 1285 Query: 1049 AAQAY-GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-------------------- 1087 GR G PG GLPGP GDPG QG+ G KGE+G PG Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1088 --------IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 I LPGSPG PGT G PG G PGP GPPG G C P Sbjct: 1346 GDPGTLKIISLPGSPGPPGTP--GEPGMQGEPGPPGPPGNLGPCGP 1389 Score = 586 bits (1510), Expect = e-167 Identities = 398/991 (40%), Positives = 461/991 (46%), Gaps = 183/991 (18%) Query: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLH--GAPGFPGQKGEQGFEGSKGETGEKGE-Q 345 P GL GAPG PG KG KGE G G G PG PG G G GS G G G+ Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP--------PGPPALPGSLGIQG 397 KG P G++GL G LG G PG G KG+ G PGPP LPG G+ G Sbjct: 443 FRKGPP------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Query: 398 PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 +G PG++G G +G G PG G PG PG PG QG G K E + G Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG---EKGETLQPEGQVGVP 553 Query: 456 ---GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP 512 GL+G G GL G PG+ G KG G GE GEKGD+G PG GS G G G Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613 Query: 513 GPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG-------LPGEHGIPGKQGIKGEKGDP 563 GPPG G PGL+G QG G+ GP G G G +PG G PG G G +G P Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 564 G-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP------KGERGLPG 612 G G G PGLPGP GE G PG PG PG G+ G PG +G GE GLPG Sbjct: 674 GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG---LPGLPGTPGTPGNDGVPGRDGK 669 G PG G + +PG G G GE G G G LPGLPG PGTPGN+G+ G G Sbjct: 734 KPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGD 793 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK-----YDS 724 PG PGPPG+ G G ++ G +PGL KG++G G+ G Sbjct: 794 PGQPGPPGEQ------GPPGRCIEGPRG--AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGP 778 + R G G G PGIPG +G G G+RGYPG PG E G G+ G PG G PGP Sbjct: 846 LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905 Query: 779 TGPPGLMGRTGHPGPTGAKGE------KGSDGPPGKPGPP---------GPPGI------ 817 G PG G+ G PG G KG+ KG G G PGP G PG+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 818 PFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG---- 869 P + N GM L +KG PGP GPPGP+GD G G PG GL G+ G Sbjct: 966 PGEKGNRGVPGMPGLKGLKG------LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGN 1019 Query: 870 --FPGVKGDRGPAGPPGIAGMSG--------------------KPGAPGPPGVPGEPGER 907 PG KG RG G PG AG G +PG PGP G PG PG+ Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079 Query: 908 GPVGDIGFPGPEG------PSGKPGINGKDGIPGA------------QGIMGKPGDRGPK 949 G G++G PGP G P G PG G G+PG +G++G PG RGP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 950 GERGDQGIPGD---RGSQGERGKPGLTGMKGAIG----PMGPPGNKGSMGSPGHQGPPGS 1002 G G G PG RG QG G PG G KG G P GP GN G+ G+ G +G PG Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKD 1062 PG+PG +K + + F LP A++ Q G GPPG Sbjct: 1200 PGLPG-----------RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSR 1247 Query: 1063 GLPGPPGDPGPQG-----YRGQKGERGEPG----------------IGLPGSPGLPGTSA 1101 G PG PG PGP G +G KG G PG +G PG+PGLPG Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG 1307 Query: 1102 -LGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 G G PG G +G PG G P + P Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP 1338 Score = 585 bits (1509), Expect = e-167 Identities = 396/992 (39%), Positives = 471/992 (47%), Gaps = 192/992 (19%) Query: 291 KGEAGLPGAPG---SPGQKGHKGEPG--------ENGLHGAPGFPGQKGEQGFEGSKGE- 338 KG+ G PG PG + G +G G PG GL GAPG+PG KG +G G G+ Sbjct: 353 KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412 Query: 339 -TGEKGEQGEKGDPALAGL----------------NGENGLKGDLGPHGPPGPKGEKGDT 381 G G G G P L G G++GL G LG G PG G KG+ Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 382 G--------PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G PGPP LPG G+ G +G PG++G G +G G PG G PG PG PG QG Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532 Query: 434 IHQTLGGYYNKDNKGNDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTK 488 G K E + G GL+G G GL G PG+ G KG G GE Sbjct: 533 DPGLKG---EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 489 GEKGDRGEPGVIGSQGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG--- 543 GEKGD+G PG GS G G G GPPG G PGL+G QG G+ GP G G G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELS 649 Query: 544 ----LPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDG 594 +PG G PG G G +G PG G G PGLPGP GE G PG PG PG G Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 595 NPGAPGPR------GPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPR-- 646 + G PG + G GE GLPG G PG G + +PG G G GE G G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 647 -GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPG 705 GLPGLPG PGTPGN+G+ G G PG PGPPG+ G G ++ G +PG Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ------GPPGRCIEGPRG--AQGLPG 821 Query: 706 LKSNKGEEGGAGEPGK-----YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP-- 758 L KG++G G+ G + R G G G PGIPG +G G G+RGYPG P Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 759 -GEKGDEGLQGIPGIPGAPGPTGP---------------PGLMGRTGHPGPTGAKGEKGS 802 G G++G+ G+ G PGA GP GP PG+ G+ G PG G +G+KG+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 803 DGP---------PGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGP 849 GP G+PG G G P + N GM L +KG PGP GPPGP Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG------LPGPAGPPGP 995 Query: 850 KGDPGPVGEPGAMGLPGLE------GFPGVKGDRGPAGPPGIAGMSG------------- 890 +GD G G PG GL G+ G PG KG RG G PG AG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 891 -------KPGAPGPPGVPGEPGERGPVGDIGFP------GPEGPSGKPGINGKDGIP--- 934 +PG PGP G PG PG+ G G++G P GP GP G PG G G+P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 935 ---------GAQGIMGKPGDRGPKGERGDQGIPGD---RGSQGERGKPGLTGMKGAIG-- 980 G +G++G PG RGP G G G PG RG QG G PG G KG G Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 981 --PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFL 1038 P GP GN G+ G+ G +G PG PG+PG +K + + F Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPTGIEGFP 1224 Query: 1039 SQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYR--GQKGERGEPGIGLPGSPGL 1096 LP A++ Q G GPPG G PG PG PGP G G KG++G +G PG G Sbjct: 1225 GPPGLPGAIIPGQT-GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--SMGHPGPKGP 1281 Query: 1097 PGTSA-------LGLPGSPGAPGPQGPPGPSG 1121 PGT+ LG PG+PG PGP+G PG G Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Score = 585 bits (1508), Expect = e-167 Identities = 395/964 (40%), Positives = 465/964 (48%), Gaps = 192/964 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG------EKGE 344 +G +GLPG GSPG G G G GL G PG G KGEQGF G G G G Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 345 QGEKGDPALA-----GLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQ 399 +G+KG PA G+ GL G GP G PGP G G GPPGPP G G GP+ Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 400 GPPGKEGQR--GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 GP G G+R G +G+ G G GPPGPPG + TL G N+ + ++ + G Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGT-----VIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 456 ---------GLKGDK--GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 GL G+ E G PG PG G G+ G PG P ++G KG+RG PG++G G Sbjct: 268 GEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 505 VKGEPGDPGPPGLIG---------------SPGLKGQQGSAGSMGPRGPPGDVGLPGEH- 548 +KG+ GD GPPG G +PG G +G+ G GP GPPG G PG Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387 Query: 549 -------GIPGKQGIKGEKGDPG----------GIIGPPGLPGPKGEAGPPG-----KSL 586 G PG +G KGE+G PG G G PGLPG G GPPG K Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447 Query: 587 PGE---PGLDGNPGAPGPRGPKGERGL--------PGVHGSPGDIGPQGI-GIPGRTGAQ 634 PG+ PG G+PG PG GPKGE GL PG G PG G G+ GIPGR GA Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP----GLPGPPGDPIALPLLGDIGA 690 G G PG G GLPG PG PG G+ G+ G G+ G G PGDP L G G Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP---GLRGQPG- 563 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 + + G+ G +G G G+ KGD GP G PG PG GP G G Sbjct: 564 ---------RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG-LMGRTGHPGPTGAKGEKGSDGPPGKP 809 GY G GE G +G QG+PG PG PG GP G L T PGP G G PPG P Sbjct: 615 PPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG------PPGHP 667 Query: 810 GPPGPPGIPFN-ERNGMSSLYKIKGGVNVPS--YPGPPGPPGPKGDPGPVGE---PGAMG 863 GP GPPGIP + + G L G +P +PGPPGP G +G PG G PG MG Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 864 LPGLEGFPGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGE 906 PGL G PG+ G +G P GP PG G SG+ PG PG PG PG G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 907 RGPVGDIGFPGPEGPSGKPGI-----NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-D 960 GP GD G PGP G G PG G G+PG G+ G+ G RG G +GD GIPG D Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 961 R-GSQGERGKPGLTGMKGAIGPMGP---PGNKGSMGSPGHQG------------PPGSPG 1004 R G GE G PG+ G +G +GP+G PGN G +G PG G PPG PG Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 1005 IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 PG P +R + + +K G+ G PG G Sbjct: 908 NPGTPG---------------------QRGSPGIPGVK-----------GQRGTPGAKGE 935 Query: 1065 PGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSP------GAPGPQGPP 1117 G G+PGP G++GEPG+ G G+PG G G+PG P G PGP GPP Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR--GVPGMPGLKGLKGLPGPAGPP 993 Query: 1118 GPSG 1121 GP G Sbjct: 994 GPRG 997 Score = 583 bits (1504), Expect = e-166 Identities = 413/1010 (40%), Positives = 469/1010 (46%), Gaps = 212/1010 (20%) Query: 282 KDQCQCIP---NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 K QC C KGE G PG PGSPGQKG G G G G GFPG G GSKG Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGL---PGLTGSKGV 92 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP---PALPGSLGI 395 G G G G P L G G G G +G G G KGE+G G PG P +PG+ G+ Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 396 QGPQGPPGKE--------------GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGY 441 +G +G P KE G G +G GPPG PGP GPPGPPG G +G Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 442 YNKDNKGNDEHEAGGLKGDKGETGLPGFPGSV-----------------GPKGQKGEPGE 484 K + G G +G KG TG PG PG+V G KG GEPG Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 485 PFTKG--------EKGDRGEPGVIGSQGVKGEPGDPGP---------PGLIGSPGLKGQQ 527 P G EKG G+PG+ G G G PG PG PGL+G G+KGQ+ Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Query: 528 GSAGSMGPRGP---------PGDVGLPGEHGIPGKQGIKGEKGDPG-------------G 565 G G G RGP GD G PG G G +G +G G PG G Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392 Query: 566 IIGPPGLPGPKGEAGPPGK---SLPGEPGLDGN---PGAPGPRGPKGE----RGLPGVHG 615 G PGL G KGE G PGK PG PG G+ PG+PGP GP G+ +G PG HG Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPGI---QGP--RGLPGLPGTPGTPGNDGVPGRDGKP 670 PG +G PG G GP GEPG+ Q P G PGLPG PG G G+PGR G Sbjct: 453 LPGYLGS-----PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 671 GLPGPPGDPIALPLLGDIGALLKNFCGNCQA-SVPGLKSNKGE----EGGAGEPGKYDSM 725 GL G PG P G+ G L F G A PGLK KGE EG G PG Sbjct: 508 GLKGSPGSP------GNTG--LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG---DP 556 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP---- 781 +G G +G GIPG G KG G +G + GEKGD+G G PG PG+PGP GP Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 782 -------PGLMGRTGHPGPTGAKGEKGSDGP-------PGKPGPPGPPGIPFNERNGMSS 827 PGL G G PG G GE G G PG PGPPGPPG P + G Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ--GPPG 674 Query: 828 LYKIKGGVNVPSYPGP-----------PGPPGPKGD------PGPVGEPGAMGLPGLEGF 870 + G P PGP PGPPGPKGD G +G PG MG PGL G Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 871 PGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGERGPVGDI 913 PG+ G +G P GP PG G SG+ PG PG PG PG G GP GD Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 914 GFPGPEGPSGKP-----GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-DR-GSQGE 966 G PGP G G P G G G+PG G+ G+ G RG G +GD GIPG DR G GE Sbjct: 795 GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854 Query: 967 RGKPGLTGMKGAIGP------------MGPPGNK---GSMGSPGHQGPPGSPGIPGIPAD 1011 G PG+ G +G +GP +GPPG G MG PG GPPG PG PG P Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 S + Q P A G PGP + G G+P Sbjct: 915 RGS-----------------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 1072 GPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G +G+ G GE+G G+ PG PGL G GLPG G PGP+G G +G Sbjct: 958 GLKGFAGNPGEKGNRGV--PGMPGLKGLK--GLPGPAGPPGPRGDLGSTG 1003 Score = 579 bits (1492), Expect = e-165 Identities = 390/958 (40%), Positives = 467/958 (48%), Gaps = 159/958 (16%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGEN--GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 KGE G GA G PG G G PGE+ GAPG PG +G+ G +G G G +G +G + Sbjct: 258 KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKG------EKGDTGPPGPPALPGSLGIQGPQGPP 402 G P L G +G G KGD+GP G GP EKGD G PGPP G+ G QGP GPP Sbjct: 318 GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377 Query: 403 GKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKG 462 G G G +PG G PG PG++G +K +G +A G G G Sbjct: 378 GVPGSPGS-------SRPGLRGAPGWPGLKG---------SKGERGRPGKDAMGTPGSPG 421 Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KGEPG------ 510 G PG PGS GP G G+ F KG GD G PG +GS G+ KGEPG Sbjct: 422 CAGSPGLPGSPGPPGPPGDI--VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQC 479 Query: 511 --DPGPPGLIGSPGLKG------QQGSAGSMGPRGPPGDVGLPGEHGIPGKQG---IKGE 559 PGPPGL G PGL G +QG+AG G G PG+ GLPG G PG QG +KGE Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGE 539 Query: 560 KGD---PGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGP---RGPKGERGLPG 612 KG+ P G +G PG PG +G+ G G +PG PG+ G PG G G KG++G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG-------------TPG 659 GSPG GP G P GP GEPG+QG +G+PG PG PG PG Sbjct: 600 DPGSPGSPGPAG---PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEP 719 G PG G PG GPPG P +L GD G L G G G +G G P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPG--LPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSK-----GERGYPGIPGEKGDEG------LQG 768 G S+ G +G G PG PG G KG G G PG PGE+G+ G L G Sbjct: 715 GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG 774 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE--------------------KGSDGPPGK 808 +PG+PG PG G G G G PGP G +G KG G GK Sbjct: 775 LPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG---DPGPVGEPGAMGLP 865 GP G PGIP +R+G G +P + G GP G +G +PG +G PG G+ Sbjct: 835 TGPKGDPGIPGLDRSGFPGE---TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891 Query: 866 GLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE------ 919 G+ GFPG G GP G PG G G PG PG G G PG +G GD G PGP Sbjct: 892 GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951 Query: 920 GPSGKPGINGKDGIPGAQG---IMGKPGDRGPKGERGDQGIPGDRG---SQGERGKPGLT 973 G G+PG+ G G PG +G + G PG +G KG G G PG RG S G G+PGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 974 GMKGAIGPMGPPGNKG---SMGSPGHQGPPGSPGIPGIPADA--VSFEEIKKY------- 1021 G+ G++G MG PG+KG ++G PG G PG PGI G+ D + E + Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 1022 ---INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG 1078 + ++ + E + Q P + A G PG PG GLPG PG G G++G Sbjct: 1072 DPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKG 1125 Query: 1079 QKGERGEPGI----GLPGSPGLPGTSAL-GLPGSPGAPGPQG----------PPGPSG 1121 KG G PGI GLPG PG PG + G G G PGP G PPGP G Sbjct: 1126 IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Score = 525 bits (1352), Expect = e-148 Identities = 335/811 (41%), Positives = 398/811 (49%), Gaps = 129/811 (15%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGF-----PGQKGEQGFEGSKGETGEKGEQG 346 G G PG PGS G+ G G PG +G G PG PG KG+QGF G+KG G G+ G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 347 EKGDPALAGLNGENGLKGDLGPHGP--PGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 E G P GL G G P GP PG GE+G++G G LPG G+ G G G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 405 EGQRGRRGKTGPPGKPGPPGP--PGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG----- 455 +G RG G+ GPPG+ GPPG GP G QG+ G G + K + + G Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE------PGVIGSQGVKG 507 G G+ G G+PG G +GP GQ+G PG P G G+ G PG IG G G Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG------------DVGLPGEHGIPGKQG 555 PG PG G G PG+KGQ+G+ G+ G +G G D G PG G G G Sbjct: 908 NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 556 IKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA------PGP 601 KG +G PG G+ GP G PGP+G+ G G PGEPGL G PG+ PG Sbjct: 968 EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN--PGEPGLRGIPGSMGNMGMPGS 1025 Query: 602 RGPKG---------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLP 652 +G +G GLPG+HG GD G G R G GP G+PG+ G G G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085 Query: 653 GTPGTPGN------DGVPGRDGKPGLPGPPGDPIALPLLGDIGAL----------LKNFC 696 G PG PG+ +G PG G PGLPG PG L G G L L F Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145 Query: 697 GNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG----PRGPPGIPGREGPKGSKGER 752 G+ PG +G++G G PG KG+ G P GP G PG +G KG +G Sbjct: 1146 GS-----PGPMGIRGDQGRDGIPGP---AGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP 1197 Query: 753 GYPGIPGEKG---DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKP 809 G+PG+PG KG D G +G GI G PGP G PG + PG TG +G GS G PG P Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAP 1253 Query: 810 GPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG 869 GPPGPPG S + IKG G PGP GP G G +G PG +G PG G Sbjct: 1254 GPPGPPG---------SHVIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 870 FPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGING 929 PG +GD PG G PGV GE G G +G IG PGP GP G PG+ G Sbjct: 1302 LPGPRGD---------------PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346 Query: 930 KDG------IPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMG 983 G +PG+ G G PG+ G +GE G G PG+ G G RGKPG G G GP G Sbjct: 1347 DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 984 PPGNKGSMGSPGHQGPPGSPGIPGIPADAVS 1014 GNKGS G PG G G PG+ G D+ S Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 516 bits (1328), Expect = e-146 Identities = 317/724 (43%), Positives = 372/724 (51%), Gaps = 81/724 (11%) Query: 295 GLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALA 354 G PG PG PG++G+ GE GE GL G PG PG G +G +G +G+ G+ G GE+G P Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 355 --------GLNGENGLKGDLGPHGPPGPKGEKG-----------DTGPPGPPA------- 388 GL G NGLKG G G GPKG+ G +TG PG P Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 389 -----LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGP------PGIQGIHQT 437 PG+ GI GP G G G G G GPPG PG PG PG PG++G T Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 438 LGGYYNKDNKGND-EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE 496 G + +KGN E + GDKGE GL GF G+ G KG +G PG P KG KG G Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 G G +G G G+PG PGL G PG G G GS G RG G G G G+PG G+ Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 557 KGEKGDPGGIIGP-PGLPGPKGEAGPPGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVH 614 +G+KG+PG G PG PGP G+ G PG GE G G PG GP GP+G G PG Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 615 GSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 G PG GP G +G G G GP PGI+GP PGLPG PG+PG G+ G G+ G+P Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGP---PGIRGP---PGLPGFPGSPGPMGIRGDQGRDGIP 1163 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GP G+ G+ G LL+ G PG + KG+ G G PG GD GP Sbjct: 1164 GPAGEK------GETG-LLRAPPG--PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL--------M 785 RGP GI G GP G G IPG+ G+ G G G PGAPGP GPPG Sbjct: 1215 RGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 786 GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKGGVNVPSYPG-- 842 G GHPGP G G G GPPG+ G PG PG+P + G +KG P + G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 843 -PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PPGP GPKG PG G+PG + + L G P GP G PG GM G+PG PGPPG Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSP------GPPGTPGEPGMQGEPGPPGPPGNL 1384 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 G G RG G G PG GP+G+ G G G PG G G P G KG+RGD G P Sbjct: 1385 GPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLP---GLKGKRGDSGSPATW 1441 Query: 962 GSQG 965 ++G Sbjct: 1442 TTRG 1445 Score = 465 bits (1197), Expect = e-131 Identities = 324/838 (38%), Positives = 373/838 (44%), Gaps = 194/838 (23%) Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG 468 G +G+ G G PGPPG PG KG TG G Sbjct: 43 GAKGEKGEKGFPGPPGSPG--------------------------------QKGFTGPEG 70 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 PG GPKG G PG +KG +G G PG GS G+ G PG+ GP GL+G PG G +G Sbjct: 71 LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE--------KGDPG--GIIGPPGLPGPKGE 578 G G G G G+PG G+ G++G + KGDPG G GP GLPGP G Sbjct: 131 EQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGF 190 Query: 579 AGPPGKSLPGEPGLDGNPGAPGPRGPKG-----------ERGLPGVHGSPGD-------- 619 GP G PG PG G PGA GPRGPKG ERG+ G+ G PG Sbjct: 191 PGPVGP--PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLP-----GTPGTPGNDGVPGRDGKPGLP 673 GP + G G +G GEPG GP GLPG G PG PG G PG+DG PG P Sbjct: 249 TGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 G G G +G + + G K + G G G YD+ KGD G Sbjct: 309 GSEGVKGNRGFPGLMG----------EDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 GPPG G GP+G G G PG PG GL+G PG PG G G G G+ G Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKDAM-GT 416 Query: 794 TGAKGEKGSDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG- 851 G+ G GS G PG PGPPGPPG I F R G + + G + P PG GP G G Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVF--RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 852 -------DPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEP 904 PGP G PG GL G++G PG +G G G PG G +G PG PG PG G+P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534 Query: 905 GERG-------PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP---KGERGD 954 G +G P G +G PG G G+PG G DGIPG G+ G PG +G GE+GD Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 955 QGIPGDRGSQGE--------------RGKPGLTGMKGAIGPMGPPGNKGSMGS------- 993 QG PGD GS G +G+PGL G +G G GPPG G G Sbjct: 595 QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 994 ---------PGHQGPPGSPGIPG------------------IPADAVSFEEIKKYINQEV 1026 PGH GP G PGIPG IP K Sbjct: 655 PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG----- 709 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP--------PGDPGPQGYRG 1078 ++ L P M G PG PGK GLPG PG PG G+ G Sbjct: 710 ----DQGFPGTKGSLGCPGKM------GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 1079 QKGERGEPG-IGLPGSPGLPGTSALGLPGSP------------GAPGPQGPPGPSGRC 1123 ++G GE G IGLPG PGLPGT P G PGP G GP GRC Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGT--------PGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 358 bits (919), Expect = 2e-98 Identities = 237/593 (39%), Positives = 274/593 (46%), Gaps = 96/593 (16%) Query: 291 KGEAGLPGAPG------------SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 KGE G G PG PG KG G PGE G G PG PG KG +G G G Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPP---GPPALPGSLGI 395 G +G+ G G+P GL G + G +G G PG KG++G G P G P LPG G+ Sbjct: 993 PGPRGDLGSTGNPGEPGLRG---IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 396 QGPQGPPG-KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA 454 QG +G PG EG R PGPPGP G PG+ G Sbjct: 1050 QGDKGEPGYSEGTR-----------PGPPGPTGDPGLPG--------------------D 1078 Query: 455 GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP 514 G KG+ G+ G PG G GP+G G PG P G+ G G+ G G +G+ G PG GP Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 515 PGLIGSP------GLKGQQGSAGSMGPRGPPGDVGL----PGEHGIPGKQGIKGEKGDPG 564 PGL G P G++G QG G GP G G+ GL PG G PG QG KG++G P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP- 1197 Query: 565 GIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGN--PGAPGPRGPKGERGLPGVHGSPG 618 G G PG G G+AGP G + PG PGL G PG G RGP G RG PG G PG Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257 Query: 619 DIGPQGIGIP------GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 G IGI G G +GP G G GP G G PGTPG PG G PG G PG+ Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGV 1317 Query: 673 PGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG 732 G G+P LG IG PG KG G G+PG ++ G Sbjct: 1318 KGEKGNP---GFLGSIGP-------------PGPIGPKGPPGVRGDPGTLKIISLPGS-- 1359 Query: 733 PRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPG 792 GPPG PG G +G G G PG G G G G G PG PGP G G G G PG Sbjct: 1360 -PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 793 PTGAKGEKGSDGPPGKPGPPG---PPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 P G+ G G G G G P G F + +++ G VP Y G Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG-TVPLYSG 1470 Score = 324 bits (831), Expect = 3e-88 Identities = 217/533 (40%), Positives = 250/533 (46%), Gaps = 105/533 (19%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEP---------------GENGLHGAPGFPGQKGEQGFEG 334 N GE G G PG PG KG KG P G G G G PG G G G Sbjct: 965 NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024 Query: 335 SKGETGEKGEQGEKGDPALAGLNGENGLKGD--------LGPHGP------PGPKGEKGD 380 SKG+ G G G G P L G++G G KG+ GP GP PG G+KG+ Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGP---------PGKPGPPGPPGPPGI 431 G PGP PG LG GP+G PG G G GK GP G GPPG GPPG+ Sbjct: 1085 MGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141 Query: 432 QGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL-------PGFPGSVGPKGQKGEPGE 484 G + G + ++G D G G+KGETGL G PG+ G KG +G PG Sbjct: 1142 PGFPGSPGPMGIRGDQGRD--GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 485 PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544 P G KG G+ G G G++G PG PG PG I PG G +G GS G G PG G Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPPGSRGSPGAPGPPGP 1258 Query: 545 PGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 PG H I GIKG+KG G GP G PG G+ GPPG+ G G PG PGPRG Sbjct: 1259 PGSHVI----GIKGDKGSMGH-PGPKGPPGTAGDMGPPGRL-----GAPGTPGLPGPRGD 1308 Query: 605 KGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGV 663 G +G PGV G G+ G G IG PG G +GP G G G + LPG+PG PG G Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Query: 664 PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 PG G+PG PGPPG N G G G+PGK Sbjct: 1369 PGMQGEPGPPGPPG-------------------------------NLGPCGPRGKPGK-- 1395 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP 776 G PG PG G KG+KG +G PG G G GL+G G G+P Sbjct: 1396 ----------DGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 266 bits (680), Expect = 8e-71 Identities = 173/413 (41%), Positives = 201/413 (48%), Gaps = 72/413 (17%) Query: 289 PNKGEAGLPGAPGS------PGQKGHKGE------------------PGENGLHGAPGFP 324 P E PG PG PG G KGE PG G G PG P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 325 GQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTG-- 382 G G+ GF+G KG G G +G G P G G G++GD G G PGP GEKG+TG Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 383 --PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP---PGPPGIQGIHQT 437 PPGP PG+ G +G +G PG G GR+G G G GP G PGPPG+ G Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AI 1233 Query: 438 LGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGS--VGPKGQKGEPGEPFTK---GEKG 492 + G N+G G +G G G PG PGS +G KG KG G P K G G Sbjct: 1234 IPG--QTGNRG-----PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 D G PG +G+ G G PG G PG G PG+KG++G+ G +G GPPG +G G G+ Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV-- 1344 Query: 553 KQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP---RGPKGE 607 +GDPG II PG PGP G PGEPG+ G PG PGP GP G Sbjct: 1345 -------RGDPGTLKIISLPGSPGPPG--------TPGEPGMQGEPGPPGPPGNLGPCGP 1389 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G PG GP G G +G GEPG G GLPGL G G G+ Sbjct: 1390 RGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 220 bits (560), Expect = 7e-57 Identities = 148/385 (38%), Positives = 175/385 (45%), Gaps = 90/385 (23%) Query: 780 GPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G G G G PGP G+ G+KG GP G PGP GP G P G++ ++G +P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP--GLPGLTGSKGVRGISGLPG 100 Query: 840 YPGPPGPPGPKGDPGP---VGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAP- 895 + G PG PG G+ GP VG PG G G +GFPG+ G G G PG AG+ G+ GAP Sbjct: 101 FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA 160 Query: 896 ----------GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD 945 G PG+PG PG +G G GFPGP GP G PG G PGA G Sbjct: 161 KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG---FPGAMG------P 211 Query: 946 RGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN--------------KGSM 991 RGPKG G++ I G +GERG GLTG P GPPG KG Sbjct: 212 RGPKGHMGERVI----GHKGERGVKGLTG------PPGPPGTVIVTLTGPDNRTDLKGEK 261 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G G G PG PG G+P ++ E+ A Sbjct: 262 GDKGAMGEPGPPGPSGLPGESYGSEKG------------------------------APG 291 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSAL----- 1102 G G PGKDG+PG PG G +G RG G GE GI G G PG G + Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 1103 --GLPGSPGAPGPQGPPGPSGRCNP 1125 G G+PG PGP+G GP G P Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGP 376 Score = 178 bits (452), Expect = 2e-44 Identities = 118/303 (38%), Positives = 149/303 (49%), Gaps = 27/303 (8%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGF-----EGSKGETGEKGEQ 345 KG+ G PG PG PG+KG G+ G G G GFPG G G G++G G +G Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 346 GEKGDPALAGLN--GENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P G + G G KG +G GP GP G GD GPPG PG+ G+ GP+G PG Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 404 KEGQRGRRGKTGPPG------KPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGL 457 +G G +G+ G PG PGP GP GPPG++G TL + G G Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGE 1368 Query: 458 KGDKGETGLPGFPGSVGPKGQKGEPGE---PFT------KGEKGDRGEPGVIGSQGV--- 505 G +GE G PG PG++GP G +G+PG+ P T KG KG +GEPG GS G+ Sbjct: 1369 PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428 Query: 506 KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGG 565 KG+ GD G P + G + S + P P G V L QG + G G Sbjct: 1429 KGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFLFVQGNQRAHGQDLG 1488 Query: 566 IIG 568 +G Sbjct: 1489 TLG 1491 Score = 152 bits (384), Expect = 2e-36 Identities = 102/275 (37%), Positives = 121/275 (44%), Gaps = 61/275 (22%) Query: 876 DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKP---------G 926 D+G G G G+ G PGPPG PG+ G GP G PGP+GP G P G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPE---GLPGPQGPKGFPGLPGLTGSKG 91 Query: 927 INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 + G G+PG G G PG G G G G+PG GS+GE+G PGL G G G G G Sbjct: 92 VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 987 NKGSMGSPGHQ-----GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 KG G+P + G PG+PG P Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQ----------------------------- 182 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 LP G PGPPG G PG G GP+G+ G++ G +GE G+ GL G PG PG Sbjct: 183 GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Query: 1099 TSAL------------GLPGSPGAPGPQGPPGPSG 1121 T + G G GA G GPPGPSG Sbjct: 243 TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Score = 147 bits (372), Expect = 4e-35 Identities = 84/206 (40%), Positives = 96/206 (46%), Gaps = 35/206 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KG G PG G PG G G PG G G PG PG +G+ GF+G G GEKG G Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--- 1325 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPGSLGIQGPQGPPG 403 G G G +GP GPPG +G+ G G PGPP PG G+QG GPPG Sbjct: 1326 ------FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463 G G G G PGK G PG PGP G K NKG+ KG+ G Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGPAG------------EKGNKGS--------KGEPGP 1419 Query: 464 TGLPGFPGSVGPKGQKGEPGEPFTKG 489 G G PG G +G G P T+G Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 67.8 bits (164), Expect = 6e-11 Identities = 38/83 (45%), Positives = 44/83 (53%), Gaps = 8/83 (9%) Query: 1054 GRPGPPGKDGLPGPPGDPG------PQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLP 1105 G G G+ G PGPPG PG P+G G +G +G PG+ GL GS G+ G S L G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 1106 GSPGAPGPQGPPGPSGRCNPEDC 1128 GSPG PG G GP G C Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGC 125 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 612 bits (1579), Expect = e-175 Identities = 395/946 (41%), Positives = 458/946 (48%), Gaps = 164/946 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE-KGEQGEKGD 350 G G+PG G+ G KG G PG GL G PGFPG +G+ G +G KGET + +G+ G GD Sbjct: 496 GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 351 PALAGLNGENGLKG---DLGPHGPPGPKGE------KGDTGPPGPPALPGSLGIQGPQGP 401 P L G G GL G G G PGPKGE KGD GPPG P PGS G GP GP Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615 Query: 402 PGK--------EGQRGRRGKTGPPGK-------------PGPPGPPGPPGIQGIHQTLGG 440 PG +G +G G GPPG+ PGPPGPPGPPG G Q G Sbjct: 616 PGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG-PQGPPG 674 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPG--FPGSVGPKGQKGEPGEPFTKGEKGDRGEPG 498 K D GL G GE G+PG FPG GPKG +G PG + G G GEPG Sbjct: 675 IPGSLGKCGDP----GLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 499 VIGSQGVKGEPGDPGP--PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G+ G G+P PG G+PG G++G++G G G PG LPG G PG +G+ Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG---LPGLPGTPGNEGL 787 Query: 557 KGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGS 616 G +GDPG PGP GE GPPG+ + G G G PG G +G +G RG G G Sbjct: 788 DGPRGDPGQ-------PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 617 PGDIGPQGIGIPGRTGAQGPAGEPGIQGP---RGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 PG G G PG TG+ G G G GP RG PG PG G PG DGV G G PG Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GPPG P G G+ +PG+K +G G GE G KG+ GP Sbjct: 901 GPPGPPGNPGTPGQRGS----------PGIPGVKGQRGTPGAKGEQGD------KGNPGP 944 Query: 734 ---------RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 +G PG+ G G G KG RG PG+PG KG L+G+PG G PGP G G Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKG---LKGLPGPAGPPGPRGDLGS 1001 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNVPSYPGP 843 G G PG G G G+ G PG G G G P R G+ ++ ++G P Y Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEG 1061 Query: 844 --PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PGPPGP GDPG PG MG G G PG G GPAGP G G G PG PG PG Sbjct: 1062 TRPGPPGPTGDPGL---PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPH 1118 Query: 902 GE------------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD-RGP 948 G+ PG RGP G GFPG GP G G G+DGIPG G G+ G R P Sbjct: 1119 GDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAP 1178 Query: 949 KGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP--------------------PGNK 988 G RG+ G G +G +G G PGL G KGA+G GP PG Sbjct: 1179 PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT 1238 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G+ G PG +G PG+PG PG P V+ I ++ ++ K P Sbjct: 1239 GNRGPPGSRGSPGAPGPPGPPGS-------------HVIGIKGDKGSMGHPGPKGPPGTA 1285 Query: 1049 AAQAY-GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-------------------- 1087 GR G PG GLPGP GDPG QG+ G KGE+G PG Sbjct: 1286 GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1088 --------IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 I LPGSPG PGT G PG G PGP GPPG G C P Sbjct: 1346 GDPGTLKIISLPGSPGPPGTP--GEPGMQGEPGPPGPPGNLGPCGP 1389 Score = 586 bits (1510), Expect = e-167 Identities = 398/991 (40%), Positives = 461/991 (46%), Gaps = 183/991 (18%) Query: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLH--GAPGFPGQKGEQGFEGSKGETGEKGE-Q 345 P GL GAPG PG KG KGE G G G PG PG G G GS G G G+ Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP--------PGPPALPGSLGIQG 397 KG P G++GL G LG G PG G KG+ G PGPP LPG G+ G Sbjct: 443 FRKGPP------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Query: 398 PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 +G PG++G G +G G PG G PG PG PG QG G K E + G Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG---EKGETLQPEGQVGVP 553 Query: 456 ---GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP 512 GL+G G GL G PG+ G KG G GE GEKGD+G PG GS G G G Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613 Query: 513 GPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG-------LPGEHGIPGKQGIKGEKGDP 563 GPPG G PGL+G QG G+ GP G G G +PG G PG G G +G P Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 564 G-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP------KGERGLPG 612 G G G PGLPGP GE G PG PG PG G+ G PG +G GE GLPG Sbjct: 674 GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG---LPGLPGTPGTPGNDGVPGRDGK 669 G PG G + +PG G G GE G G G LPGLPG PGTPGN+G+ G G Sbjct: 734 KPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGD 793 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK-----YDS 724 PG PGPPG+ G G ++ G +PGL KG++G G+ G Sbjct: 794 PGQPGPPGEQ------GPPGRCIEGPRG--AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGP 778 + R G G G PGIPG +G G G+RGYPG PG E G G+ G PG G PGP Sbjct: 846 LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905 Query: 779 TGPPGLMGRTGHPGPTGAKGE------KGSDGPPGKPGPP---------GPPGI------ 817 G PG G+ G PG G KG+ KG G G PGP G PG+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 818 PFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG---- 869 P + N GM L +KG PGP GPPGP+GD G G PG GL G+ G Sbjct: 966 PGEKGNRGVPGMPGLKGLKG------LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGN 1019 Query: 870 --FPGVKGDRGPAGPPGIAGMSG--------------------KPGAPGPPGVPGEPGER 907 PG KG RG G PG AG G +PG PGP G PG PG+ Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079 Query: 908 GPVGDIGFPGPEG------PSGKPGINGKDGIPGA------------QGIMGKPGDRGPK 949 G G++G PGP G P G PG G G+PG +G++G PG RGP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 950 GERGDQGIPGD---RGSQGERGKPGLTGMKGAIG----PMGPPGNKGSMGSPGHQGPPGS 1002 G G G PG RG QG G PG G KG G P GP GN G+ G+ G +G PG Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKD 1062 PG+PG +K + + F LP A++ Q G GPPG Sbjct: 1200 PGLPG-----------RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSR 1247 Query: 1063 GLPGPPGDPGPQG-----YRGQKGERGEPG----------------IGLPGSPGLPGTSA 1101 G PG PG PGP G +G KG G PG +G PG+PGLPG Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRG 1307 Query: 1102 -LGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 G G PG G +G PG G P + P Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP 1338 Score = 585 bits (1509), Expect = e-167 Identities = 396/992 (39%), Positives = 471/992 (47%), Gaps = 192/992 (19%) Query: 291 KGEAGLPGAPG---SPGQKGHKGEPG--------ENGLHGAPGFPGQKGEQGFEGSKGE- 338 KG+ G PG PG + G +G G PG GL GAPG+PG KG +G G G+ Sbjct: 353 KGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD 412 Query: 339 -TGEKGEQGEKGDPALAGL----------------NGENGLKGDLGPHGPPGPKGEKGDT 381 G G G G P L G G++GL G LG G PG G KG+ Sbjct: 413 AMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEP 472 Query: 382 G--------PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 G PGPP LPG G+ G +G PG++G G +G G PG G PG PG PG QG Sbjct: 473 GLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQG 532 Query: 434 IHQTLGGYYNKDNKGNDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTK 488 G K E + G GL+G G GL G PG+ G KG G GE Sbjct: 533 DPGLKG---EKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS 589 Query: 489 GEKGDRGEPGVIGSQGVKGEPGDPGPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG--- 543 GEKGD+G PG GS G G G GPPG G PGL+G QG G+ GP G G G Sbjct: 590 GEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELS 649 Query: 544 ----LPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDG 594 +PG G PG G G +G PG G G PGLPGP GE G PG PG PG G Sbjct: 650 VSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG 709 Query: 595 NPGAPGPR------GPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPR-- 646 + G PG + G GE GLPG G PG G + +PG G G GE G G Sbjct: 710 DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGE 769 Query: 647 -GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPG 705 GLPGLPG PGTPGN+G+ G G PG PGPPG+ G G ++ G +PG Sbjct: 770 IGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ------GPPGRCIEGPRG--AQGLPG 821 Query: 706 LKSNKGEEGGAGEPGK-----YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP-- 758 L KG++G G+ G + R G G G PGIPG +G G G+RGYPG P Sbjct: 822 LNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGI 881 Query: 759 -GEKGDEGLQGIPGIPGAPGPTGP---------------PGLMGRTGHPGPTGAKGEKGS 802 G G++G+ G+ G PGA GP GP PG+ G+ G PG G +G+KG+ Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 803 DGP---------PGKPGPPGPPGIPFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGP 849 GP G+PG G G P + N GM L +KG PGP GPPGP Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG------LPGPAGPPGP 995 Query: 850 KGDPGPVGEPGAMGLPGLE------GFPGVKGDRGPAGPPGIAGMSG------------- 890 +GD G G PG GL G+ G PG KG RG G PG AG G Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGE 1055 Query: 891 -------KPGAPGPPGVPGEPGERGPVGDIGFP------GPEGPSGKPGINGKDGIP--- 934 +PG PGP G PG PG+ G G++G P GP GP G PG G G+P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 935 ---------GAQGIMGKPGDRGPKGERGDQGIPGD---RGSQGERGKPGLTGMKGAIG-- 980 G +G++G PG RGP G G G PG RG QG G PG G KG G Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 981 --PMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFL 1038 P GP GN G+ G+ G +G PG PG+PG +K + + F Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPG-----------RKGAMGDAGPRGPTGIEGFP 1224 Query: 1039 SQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYR--GQKGERGEPGIGLPGSPGL 1096 LP A++ Q G GPPG G PG PG PGP G G KG++G +G PG G Sbjct: 1225 GPPGLPGAIIPGQT-GNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--SMGHPGPKGP 1281 Query: 1097 PGTSA-------LGLPGSPGAPGPQGPPGPSG 1121 PGT+ LG PG+PG PGP+G PG G Sbjct: 1282 PGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQG 1313 Score = 585 bits (1508), Expect = e-167 Identities = 395/964 (40%), Positives = 465/964 (48%), Gaps = 192/964 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG------EKGE 344 +G +GLPG GSPG G G G GL G PG G KGEQGF G G G G Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 345 QGEKGDPALA-----GLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQ 399 +G+KG PA G+ GL G GP G PGP G G GPPGPP G G GP+ Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 400 GPPGKEGQR--GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 GP G G+R G +G+ G G GPPGPPG + TL G N+ + ++ + G Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGT-----VIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 456 ---------GLKGDK--GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 GL G+ E G PG PG G G+ G PG P ++G KG+RG PG++G G Sbjct: 268 GEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 505 VKGEPGDPGPPGLIG---------------SPGLKGQQGSAGSMGPRGPPGDVGLPGEH- 548 +KG+ GD GPPG G +PG G +G+ G GP GPPG G PG Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387 Query: 549 -------GIPGKQGIKGEKGDPG----------GIIGPPGLPGPKGEAGPPG-----KSL 586 G PG +G KGE+G PG G G PGLPG G GPPG K Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447 Query: 587 PGE---PGLDGNPGAPGPRGPKGERGL--------PGVHGSPGDIGPQGI-GIPGRTGAQ 634 PG+ PG G+PG PG GPKGE GL PG G PG G G+ GIPGR GA Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP----GLPGPPGDPIALPLLGDIGA 690 G G PG G GLPG PG PG G+ G+ G G+ G G PGDP L G G Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP---GLRGQPG- 563 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 + + G+ G +G G G+ KGD GP G PG PG GP G G Sbjct: 564 ---------RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG-LMGRTGHPGPTGAKGEKGSDGPPGKP 809 GY G GE G +G QG+PG PG PG GP G L T PGP G G PPG P Sbjct: 615 PPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG------PPGHP 667 Query: 810 GPPGPPGIPFN-ERNGMSSLYKIKGGVNVPS--YPGPPGPPGPKGDPGPVGE---PGAMG 863 GP GPPGIP + + G L G +P +PGPPGP G +G PG G PG MG Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 864 LPGLEGFPGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGE 906 PGL G PG+ G +G P GP PG G SG+ PG PG PG PG G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 907 RGPVGDIGFPGPEGPSGKPGI-----NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-D 960 GP GD G PGP G G PG G G+PG G+ G+ G RG G +GD GIPG D Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 961 R-GSQGERGKPGLTGMKGAIGPMGP---PGNKGSMGSPGHQG------------PPGSPG 1004 R G GE G PG+ G +G +GP+G PGN G +G PG G PPG PG Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 1005 IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 PG P +R + + +K G+ G PG G Sbjct: 908 NPGTPG---------------------QRGSPGIPGVK-----------GQRGTPGAKGE 935 Query: 1065 PGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSP------GAPGPQGPP 1117 G G+PGP G++GEPG+ G G+PG G G+PG P G PGP GPP Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR--GVPGMPGLKGLKGLPGPAGPP 993 Query: 1118 GPSG 1121 GP G Sbjct: 994 GPRG 997 Score = 583 bits (1504), Expect = e-166 Identities = 413/1010 (40%), Positives = 469/1010 (46%), Gaps = 212/1010 (20%) Query: 282 KDQCQCIP---NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 K QC C KGE G PG PGSPGQKG G G G G GFPG G GSKG Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGL---PGLTGSKGV 92 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP---PALPGSLGI 395 G G G G P L G G G G +G G G KGE+G G PG P +PG+ G+ Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 396 QGPQGPPGKE--------------GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGY 441 +G +G P KE G G +G GPPG PGP GPPGPPG G +G Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 442 YNKDNKGNDEHEAGGLKGDKGETGLPGFPGSV-----------------GPKGQKGEPGE 484 K + G G +G KG TG PG PG+V G KG GEPG Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 485 PFTKG--------EKGDRGEPGVIGSQGVKGEPGDPGP---------PGLIGSPGLKGQQ 527 P G EKG G+PG+ G G G PG PG PGL+G G+KGQ+ Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Query: 528 GSAGSMGPRGP---------PGDVGLPGEHGIPGKQGIKGEKGDPG-------------G 565 G G G RGP GD G PG G G +G +G G PG G Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392 Query: 566 IIGPPGLPGPKGEAGPPGK---SLPGEPGLDGN---PGAPGPRGPKGE----RGLPGVHG 615 G PGL G KGE G PGK PG PG G+ PG+PGP GP G+ +G PG HG Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPGI---QGP--RGLPGLPGTPGTPGNDGVPGRDGKP 670 PG +G PG G GP GEPG+ Q P G PGLPG PG G G+PGR G Sbjct: 453 LPGYLGS-----PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 671 GLPGPPGDPIALPLLGDIGALLKNFCGNCQA-SVPGLKSNKGE----EGGAGEPGKYDSM 725 GL G PG P G+ G L F G A PGLK KGE EG G PG Sbjct: 508 GLKGSPGSP------GNTG--LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG---DP 556 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP---- 781 +G G +G GIPG G KG G +G + GEKGD+G G PG PG+PGP GP Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 782 -------PGLMGRTGHPGPTGAKGEKGSDGP-------PGKPGPPGPPGIPFNERNGMSS 827 PGL G G PG G GE G G PG PGPPGPPG P + G Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ--GPPG 674 Query: 828 LYKIKGGVNVPSYPGP-----------PGPPGPKGD------PGPVGEPGAMGLPGLEGF 870 + G P PGP PGPPGPKGD G +G PG MG PGL G Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 871 PGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGERGPVGDI 913 PG+ G +G P GP PG G SG+ PG PG PG PG G GP GD Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 914 GFPGPEGPSGKP-----GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-DR-GSQGE 966 G PGP G G P G G G+PG G+ G+ G RG G +GD GIPG DR G GE Sbjct: 795 GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854 Query: 967 RGKPGLTGMKGAIGP------------MGPPGNK---GSMGSPGHQGPPGSPGIPGIPAD 1011 G PG+ G +G +GP +GPPG G MG PG GPPG PG PG P Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 S + Q P A G PGP + G G+P Sbjct: 915 RGS-----------------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 1072 GPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G +G+ G GE+G G+ PG PGL G GLPG G PGP+G G +G Sbjct: 958 GLKGFAGNPGEKGNRGV--PGMPGLKGLK--GLPGPAGPPGPRGDLGSTG 1003 Score = 579 bits (1492), Expect = e-165 Identities = 390/958 (40%), Positives = 467/958 (48%), Gaps = 159/958 (16%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGEN--GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 KGE G GA G PG G G PGE+ GAPG PG +G+ G +G G G +G +G + Sbjct: 258 KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKG------EKGDTGPPGPPALPGSLGIQGPQGPP 402 G P L G +G G KGD+GP G GP EKGD G PGPP G+ G QGP GPP Sbjct: 318 GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377 Query: 403 GKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKG 462 G G G +PG G PG PG++G +K +G +A G G G Sbjct: 378 GVPGSPGS-------SRPGLRGAPGWPGLKG---------SKGERGRPGKDAMGTPGSPG 421 Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KGEPG------ 510 G PG PGS GP G G+ F KG GD G PG +GS G+ KGEPG Sbjct: 422 CAGSPGLPGSPGPPGPPGDI--VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQC 479 Query: 511 --DPGPPGLIGSPGLKG------QQGSAGSMGPRGPPGDVGLPGEHGIPGKQG---IKGE 559 PGPPGL G PGL G +QG+AG G G PG+ GLPG G PG QG +KGE Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGE 539 Query: 560 KGD---PGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGP---RGPKGERGLPG 612 KG+ P G +G PG PG +G+ G G +PG PG+ G PG G G KG++G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG-------------TPG 659 GSPG GP G P GP GEPG+QG +G+PG PG PG PG Sbjct: 600 DPGSPGSPGPAG---PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEP 719 G PG G PG GPPG P +L GD G L G G G +G G P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPG--LPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSK-----GERGYPGIPGEKGDEG------LQG 768 G S+ G +G G PG PG G KG G G PG PGE+G+ G L G Sbjct: 715 GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG 774 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE--------------------KGSDGPPGK 808 +PG+PG PG G G G G PGP G +G KG G GK Sbjct: 775 LPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG---DPGPVGEPGAMGLP 865 GP G PGIP +R+G G +P + G GP G +G +PG +G PG G+ Sbjct: 835 TGPKGDPGIPGLDRSGFPGE---TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891 Query: 866 GLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE------ 919 G+ GFPG G GP G PG G G PG PG G G PG +G GD G PGP Sbjct: 892 GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951 Query: 920 GPSGKPGINGKDGIPGAQG---IMGKPGDRGPKGERGDQGIPGDRG---SQGERGKPGLT 973 G G+PG+ G G PG +G + G PG +G KG G G PG RG S G G+PGL Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 974 GMKGAIGPMGPPGNKG---SMGSPGHQGPPGSPGIPGIPADA--VSFEEIKKY------- 1021 G+ G++G MG PG+KG ++G PG G PG PGI G+ D + E + Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 1022 ---INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG 1078 + ++ + E + Q P + A G PG PG GLPG PG G G++G Sbjct: 1072 DPGLPGDMGKKGE------MGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKG 1125 Query: 1079 QKGERGEPGI----GLPGSPGLPGTSAL-GLPGSPGAPGPQG----------PPGPSG 1121 KG G PGI GLPG PG PG + G G G PGP G PPGP G Sbjct: 1126 IKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRG 1183 Score = 525 bits (1352), Expect = e-148 Identities = 335/811 (41%), Positives = 398/811 (49%), Gaps = 129/811 (15%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGF-----PGQKGEQGFEGSKGETGEKGEQG 346 G G PG PGS G+ G G PG +G G PG PG KG+QGF G+KG G G+ G Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 347 EKGDPALAGLNGENGLKGDLGPHGP--PGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 E G P GL G G P GP PG GE+G++G G LPG G+ G G G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 405 EGQRGRRGKTGPPGKPGPPGP--PGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG----- 455 +G RG G+ GPPG+ GPPG GP G QG+ G G + K + + G Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 456 --GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE------PGVIGSQGVKG 507 G G+ G G+PG G +GP GQ+G PG P G G+ G PG IG G G Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG------------DVGLPGEHGIPGKQG 555 PG PG G G PG+KGQ+G+ G+ G +G G D G PG G G G Sbjct: 908 NPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 556 IKGEKGDPG--------GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA------PGP 601 KG +G PG G+ GP G PGP+G+ G G PGEPGL G PG+ PG Sbjct: 968 EKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGN--PGEPGLRGIPGSMGNMGMPGS 1025 Query: 602 RGPKG---------ERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLP 652 +G +G GLPG+HG GD G G R G GP G+PG+ G G G Sbjct: 1026 KGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEM 1085 Query: 653 GTPGTPGN------DGVPGRDGKPGLPGPPGDPIALPLLGDIGAL----------LKNFC 696 G PG PG+ +G PG G PGLPG PG L G G L L F Sbjct: 1086 GQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFP 1145 Query: 697 GNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG----PRGPPGIPGREGPKGSKGER 752 G+ PG +G++G G PG KG+ G P GP G PG +G KG +G Sbjct: 1146 GS-----PGPMGIRGDQGRDGIPGP---AGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP 1197 Query: 753 GYPGIPGEKG---DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKP 809 G+PG+PG KG D G +G GI G PGP G PG + PG TG +G GS G PG P Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAP 1253 Query: 810 GPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG 869 GPPGPPG S + IKG G PGP GP G G +G PG +G PG G Sbjct: 1254 GPPGPPG---------SHVIGIKGD---KGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 870 FPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGING 929 PG +GD PG G PGV GE G G +G IG PGP GP G PG+ G Sbjct: 1302 LPGPRGD---------------PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRG 1346 Query: 930 KDG------IPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMG 983 G +PG+ G G PG+ G +GE G G PG+ G G RGKPG G G GP G Sbjct: 1347 DPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAG 1406 Query: 984 PPGNKGSMGSPGHQGPPGSPGIPGIPADAVS 1014 GNKGS G PG G G PG+ G D+ S Sbjct: 1407 EKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 516 bits (1328), Expect = e-146 Identities = 317/724 (43%), Positives = 372/724 (51%), Gaps = 81/724 (11%) Query: 295 GLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALA 354 G PG PG PG++G+ GE GE GL G PG PG G +G +G +G+ G+ G GE+G P Sbjct: 750 GGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Query: 355 --------GLNGENGLKGDLGPHGPPGPKGEKG-----------DTGPPGPPA------- 388 GL G NGLKG G G GPKG+ G +TG PG P Sbjct: 810 IEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGP 869 Query: 389 -----LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGP------PGIQGIHQT 437 PG+ GI GP G G G G G GPPG PG PG PG PG++G T Sbjct: 870 LGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929 Query: 438 LGGYYNKDNKGND-EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGE 496 G + +KGN E + GDKGE GL GF G+ G KG +G PG P KG KG G Sbjct: 930 PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989 Query: 497 PGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 G G +G G G+PG PGL G PG G G GS G RG G G G G+PG G+ Sbjct: 990 AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 557 KGEKGDPGGIIGP-PGLPGPKGEAGPPGK-SLPGEPGLDGNPGAPGPRGPKGERGLPGVH 614 +G+KG+PG G PG PGP G+ G PG GE G G PG GP GP+G G PG Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109 Query: 615 GSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLP 673 G PG GP G +G G G GP PGI+GP PGLPG PG+PG G+ G G+ G+P Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGP---PGIRGP---PGLPGFPGSPGPMGIRGDQGRDGIP 1163 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 GP G+ G+ G LL+ G PG + KG+ G G PG GD GP Sbjct: 1164 GPAGEK------GETG-LLRAPPG--PRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL--------M 785 RGP GI G GP G G IPG+ G+ G G G PGAPGP GPPG Sbjct: 1215 RGPTGIEGFPGPPGLPGAI----IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDK 1270 Query: 786 GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN-GMSSLYKIKGGVNVPSYPG-- 842 G GHPGP G G G GPPG+ G PG PG+P + G +KG P + G Sbjct: 1271 GSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI 1330 Query: 843 -PPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 PPGP GPKG PG G+PG + + L G P GP G PG GM G+PG PGPPG Sbjct: 1331 GPPGPIGPKGPPGVRGDPGTLKIISLPGSP------GPPGTPGEPGMQGEPGPPGPPGNL 1384 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 G G RG G G PG GP+G+ G G G PG G G P G KG+RGD G P Sbjct: 1385 GPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLP---GLKGKRGDSGSPATW 1441 Query: 962 GSQG 965 ++G Sbjct: 1442 TTRG 1445 Score = 465 bits (1197), Expect = e-131 Identities = 324/838 (38%), Positives = 373/838 (44%), Gaps = 194/838 (23%) Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG 468 G +G+ G G PGPPG PG KG TG G Sbjct: 43 GAKGEKGEKGFPGPPGSPG--------------------------------QKGFTGPEG 70 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 PG GPKG G PG +KG +G G PG GS G+ G PG+ GP GL+G PG G +G Sbjct: 71 LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE--------KGDPG--GIIGPPGLPGPKGE 578 G G G G G+PG G+ G++G + KGDPG G GP GLPGP G Sbjct: 131 EQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGF 190 Query: 579 AGPPGKSLPGEPGLDGNPGAPGPRGPKG-----------ERGLPGVHGSPGD-------- 619 GP G PG PG G PGA GPRGPKG ERG+ G+ G PG Sbjct: 191 PGPVGP--PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLP-----GTPGTPGNDGVPGRDGKPGLP 673 GP + G G +G GEPG GP GLPG G PG PG G PG+DG PG P Sbjct: 249 TGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 G G G +G + + G K + G G G YD+ KGD G Sbjct: 309 GSEGVKGNRGFPGLMG----------EDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 GPPG G GP+G G G PG PG GL+G PG PG G G G G+ G Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKDAM-GT 416 Query: 794 TGAKGEKGSDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG- 851 G+ G GS G PG PGPPGPPG I F R G + + G + P PG GP G G Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVF--RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 852 -------DPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEP 904 PGP G PG GL G++G PG +G G G PG G +G PG PG PG G+P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534 Query: 905 GERG-------PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP---KGERGD 954 G +G P G +G PG G G+PG G DGIPG G+ G PG +G GE+GD Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 955 QGIPGDRGSQGE--------------RGKPGLTGMKGAIGPMGPPGNKGSMGS------- 993 QG PGD GS G +G+PGL G +G G GPPG G G Sbjct: 595 QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 994 ---------PGHQGPPGSPGIPG------------------IPADAVSFEEIKKYINQEV 1026 PGH GP G PGIPG IP K Sbjct: 655 PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG----- 709 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP--------PGDPGPQGYRG 1078 ++ L P M G PG PGK GLPG PG PG G+ G Sbjct: 710 ----DQGFPGTKGSLGCPGKM------GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759 Query: 1079 QKGERGEPG-IGLPGSPGLPGTSALGLPGSP------------GAPGPQGPPGPSGRC 1123 ++G GE G IGLPG PGLPGT P G PGP G GP GRC Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGT--------PGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 358 bits (919), Expect = 2e-98 Identities = 237/593 (39%), Positives = 274/593 (46%), Gaps = 96/593 (16%) Query: 291 KGEAGLPGAPG------------SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 KGE G G PG PG KG G PGE G G PG PG KG +G G G Sbjct: 933 KGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGP 992 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPP---GPPALPGSLGI 395 G +G+ G G+P GL G + G +G G PG KG++G G P G P LPG G+ Sbjct: 993 PGPRGDLGSTGNPGEPGLRG---IPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049 Query: 396 QGPQGPPG-KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA 454 QG +G PG EG R PGPPGP G PG+ G Sbjct: 1050 QGDKGEPGYSEGTR-----------PGPPGPTGDPGLPG--------------------D 1078 Query: 455 GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGP 514 G KG+ G+ G PG G GP+G G PG P G+ G G+ G G +G+ G PG GP Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 515 PGLIGSP------GLKGQQGSAGSMGPRGPPGDVGL----PGEHGIPGKQGIKGEKGDPG 564 PGL G P G++G QG G GP G G+ GL PG G PG QG KG++G P Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAP- 1197 Query: 565 GIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGN--PGAPGPRGPKGERGLPGVHGSPG 618 G G PG G G+AGP G + PG PGL G PG G RGP G RG PG G PG Sbjct: 1198 GFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257 Query: 619 DIGPQGIGIP------GRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 G IGI G G +GP G G GP G G PGTPG PG G PG G PG+ Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGV 1317 Query: 673 PGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIG 732 G G+P LG IG PG KG G G+PG ++ G Sbjct: 1318 KGEKGNP---GFLGSIGP-------------PGPIGPKGPPGVRGDPGTLKIISLPGS-- 1359 Query: 733 PRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPG 792 GPPG PG G +G G G PG G G G G G PG PGP G G G G PG Sbjct: 1360 -PGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPG 1418 Query: 793 PTGAKGEKGSDGPPGKPGPPG---PPGIPFNERNGMSSLYKIKGGVNVPSYPG 842 P G+ G G G G G P G F + +++ G VP Y G Sbjct: 1419 PAGSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEG-TVPLYSG 1470 Score = 324 bits (831), Expect = 3e-88 Identities = 217/533 (40%), Positives = 250/533 (46%), Gaps = 105/533 (19%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEP---------------GENGLHGAPGFPGQKGEQGFEG 334 N GE G G PG PG KG KG P G G G G PG G G G Sbjct: 965 NPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPG 1024 Query: 335 SKGETGEKGEQGEKGDPALAGLNGENGLKGD--------LGPHGP------PGPKGEKGD 380 SKG+ G G G G P L G++G G KG+ GP GP PG G+KG+ Sbjct: 1025 SKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGE 1084 Query: 381 TGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGP---------PGKPGPPGPPGPPGI 431 G PGP PG LG GP+G PG G G GK GP G GPPG GPPG+ Sbjct: 1085 MGQPGP---PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141 Query: 432 QGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGL-------PGFPGSVGPKGQKGEPGE 484 G + G + ++G D G G+KGETGL G PG+ G KG +G PG Sbjct: 1142 PGFPGSPGPMGIRGDQGRD--GIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 485 PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGL 544 P G KG G+ G G G++G PG PG PG I PG G +G GS G G PG G Sbjct: 1200 PGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPPGSRGSPGAPGPPGP 1258 Query: 545 PGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 PG H I GIKG+KG G GP G PG G+ GPPG+ G G PG PGPRG Sbjct: 1259 PGSHVI----GIKGDKGSMGH-PGPKGPPGTAGDMGPPGRL-----GAPGTPGLPGPRGD 1308 Query: 605 KGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGV 663 G +G PGV G G+ G G IG PG G +GP G G G + LPG+PG PG G Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGE 1368 Query: 664 PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYD 723 PG G+PG PGPPG N G G G+PGK Sbjct: 1369 PGMQGEPGPPGPPG-------------------------------NLGPCGPRGKPGK-- 1395 Query: 724 SMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAP 776 G PG PG G KG+KG +G PG G G GL+G G G+P Sbjct: 1396 ----------DGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 266 bits (680), Expect = 8e-71 Identities = 173/413 (41%), Positives = 201/413 (48%), Gaps = 72/413 (17%) Query: 289 PNKGEAGLPGAPGS------PGQKGHKGE------------------PGENGLHGAPGFP 324 P E PG PG PG G KGE PG G G PG P Sbjct: 1056 PGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP 1115 Query: 325 GQKGEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTG-- 382 G G+ GF+G KG G G +G G P G G G++GD G G PGP GEKG+TG Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 383 --PPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGP---PGPPGIQGIHQT 437 PPGP PG+ G +G +G PG G GR+G G G GP G PGPPG+ G Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPG--AI 1233 Query: 438 LGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGS--VGPKGQKGEPGEPFTK---GEKG 492 + G N+G G +G G G PG PGS +G KG KG G P K G G Sbjct: 1234 IPG--QTGNRG-----PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG 552 D G PG +G+ G G PG G PG G PG+KG++G+ G +G GPPG +G G G+ Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV-- 1344 Query: 553 KQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGP---RGPKGE 607 +GDPG II PG PGP G PGEPG+ G PG PGP GP G Sbjct: 1345 -------RGDPGTLKIISLPGSPGPPG--------TPGEPGMQGEPGPPGPPGNLGPCGP 1389 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGN 660 RG PG G PG GP G G +G GEPG G GLPGL G G G+ Sbjct: 1390 RGKPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGS 1437 Score = 220 bits (560), Expect = 7e-57 Identities = 148/385 (38%), Positives = 175/385 (45%), Gaps = 90/385 (23%) Query: 780 GPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS 839 G G G G PGP G+ G+KG GP G PGP GP G P G++ ++G +P Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFP--GLPGLTGSKGVRGISGLPG 100 Query: 840 YPGPPGPPGPKGDPGP---VGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAP- 895 + G PG PG G+ GP VG PG G G +GFPG+ G G G PG AG+ G+ GAP Sbjct: 101 FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA 160 Query: 896 ----------GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD 945 G PG+PG PG +G G GFPGP GP G PG G PGA G Sbjct: 161 KEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG---FPGAMG------P 211 Query: 946 RGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN--------------KGSM 991 RGPKG G++ I G +GERG GLTG P GPPG KG Sbjct: 212 RGPKGHMGERVI----GHKGERGVKGLTG------PPGPPGTVIVTLTGPDNRTDLKGEK 261 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G G G PG PG G+P ++ E+ A Sbjct: 262 GDKGAMGEPGPPGPSGLPGESYGSEKG------------------------------APG 291 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSAL----- 1102 G G PGKDG+PG PG G +G RG G GE GI G G PG G + Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 1103 --GLPGSPGAPGPQGPPGPSGRCNP 1125 G G+PG PGP+G GP G P Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGP 376 Score = 178 bits (452), Expect = 2e-44 Identities = 118/303 (38%), Positives = 149/303 (49%), Gaps = 27/303 (8%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGF-----EGSKGETGEKGEQ 345 KG+ G PG PG PG+KG G+ G G G GFPG G G G++G G +G Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 346 GEKGDPALAGLN--GENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P G + G G KG +G GP GP G GD GPPG PG+ G+ GP+G PG Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 404 KEGQRGRRGKTGPPG------KPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGL 457 +G G +G+ G PG PGP GP GPPG++G TL + G G Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPG--TPGE 1368 Query: 458 KGDKGETGLPGFPGSVGPKGQKGEPGE---PFT------KGEKGDRGEPGVIGSQGV--- 505 G +GE G PG PG++GP G +G+PG+ P T KG KG +GEPG GS G+ Sbjct: 1369 PGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGL 1428 Query: 506 KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGG 565 KG+ GD G P + G + S + P P G V L QG + G G Sbjct: 1429 KGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFLFVQGNQRAHGQDLG 1488 Query: 566 IIG 568 +G Sbjct: 1489 TLG 1491 Score = 152 bits (384), Expect = 2e-36 Identities = 102/275 (37%), Positives = 121/275 (44%), Gaps = 61/275 (22%) Query: 876 DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKP---------G 926 D+G G G G+ G PGPPG PG+ G GP G PGP+GP G P G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPE---GLPGPQGPKGFPGLPGLTGSKG 91 Query: 927 INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 + G G+PG G G PG G G G G+PG GS+GE+G PGL G G G G G Sbjct: 92 VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 987 NKGSMGSPGHQ-----GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 KG G+P + G PG+PG P Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQ----------------------------- 182 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 LP G PGPPG G PG G GP+G+ G++ G +GE G+ GL G PG PG Sbjct: 183 GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Query: 1099 TSAL------------GLPGSPGAPGPQGPPGPSG 1121 T + G G GA G GPPGPSG Sbjct: 243 TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Score = 147 bits (372), Expect = 4e-35 Identities = 84/206 (40%), Positives = 96/206 (46%), Gaps = 35/206 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KG G PG G PG G G PG G G PG PG +G+ GF+G G GEKG G Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--- 1325 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPGSLGIQGPQGPPG 403 G G G +GP GPPG +G+ G G PGPP PG G+QG GPPG Sbjct: 1326 ------FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463 G G G G PGK G PG PGP G K NKG+ KG+ G Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGPAG------------EKGNKGS--------KGEPGP 1419 Query: 464 TGLPGFPGSVGPKGQKGEPGEPFTKG 489 G G PG G +G G P T+G Sbjct: 1420 AGSDGLPGLKGKRGDSGSPATWTTRG 1445 Score = 67.8 bits (164), Expect = 6e-11 Identities = 38/83 (45%), Positives = 44/83 (53%), Gaps = 8/83 (9%) Query: 1054 GRPGPPGKDGLPGPPGDPG------PQGYRGQKGERGEPGI-GLPGSPGLPGTSAL-GLP 1105 G G G+ G PGPPG PG P+G G +G +G PG+ GL GS G+ G S L G Sbjct: 43 GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102 Query: 1106 GSPGAPGPQGPPGPSGRCNPEDC 1128 GSPG PG G GP G C Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGC 125 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 610 bits (1572), Expect = e-174 Identities = 396/980 (40%), Positives = 484/980 (49%), Gaps = 161/980 (16%) Query: 291 KGEAGLPGA---PGSPGQKGHKGEPGENGLHGAPGFPGQ---KGEQGFEGSKGETGEKGE 344 +GE GLPG PG PG+ G G+PG NG +G PG PG+ KGE+G G+ G G G Sbjct: 1814 RGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGP 1873 Query: 345 QGEKGDPALAGLNGENGLKGDLGPHGP--------PGPKGEKGDTGPPGPPALPGSLGIQ 396 +GE+G P + G G GL G +GP G GPKG++G+TG G LPG G++ Sbjct: 1874 KGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLR 1933 Query: 397 GPQG------------------------------------PPGKEGQRGRRGKTGPPGKP 420 G G P + G +G G+ GPPGK Sbjct: 1934 GEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKE 1993 Query: 421 GPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQ 478 GP G PG G++G G + G GL G+ G+ G+PG PG G G+ Sbjct: 1994 GPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGE 2053 Query: 479 KGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLI--------------GSPGLK 524 G PGE +GEKG+RGE G G G+ G PG PGPPG G PGLK Sbjct: 2054 AGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLK 2113 Query: 525 GQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEA 579 G +G GS G +GP GD G+PG G G+ G +G+ G+PG G+ GP G PG +G Sbjct: 2114 GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPR 2173 Query: 580 GPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGA---QGP 636 GPPG G G G PGAPG GP G +G G+ G PG+ GP G G+ G TGA GP Sbjct: 2174 GPPGPV--GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGP 2231 Query: 637 AGEPGIQGPRGLPGLPGT------PGTPGNDGVPGRDG---KPGLPGPPGDPIALPLLGD 687 G G+ GP+G PGLPG PG PG DG G+DG PG+PG PG P + G+ Sbjct: 2232 PGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGE 2291 Query: 688 IGALLKNFCGNCQASVPGLKSNKGEEGG-----AGEPGKYDSMA------RKGDIGPRGP 736 G G +PG K KG GG GEPG KG+ G G Sbjct: 2292 PGPT--GAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE 2349 Query: 737 PGIPGREGPKGSKGERGY-----------PGIPGEKGDEGLQGIPGIPGAPGPTGPPGLM 785 PG PG +G KG+ G +G+ PG PG G +G G+PG+PGAPG G PG Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQT 2409 Query: 786 GRTGHPGPTGAKGEKGSDGPPGK---PGPPGPPGIPFNERN-GMSSLYKIKGGVNVPSYP 841 G G G G GE+G GPPG+ PGP GPPG P + G S L KG V Sbjct: 2410 GPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGV---- 2465 Query: 842 GPPGPPGPKGDPGPVGE---PGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPG----- 893 G PGP G +G+PG GE PG G GL G PG +G+RG G G AG+ G G Sbjct: 2466 GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI 2525 Query: 894 --APGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRG---P 948 PGP G G+ GERGP G G GP G +G PG G G PG +G G PG RG P Sbjct: 2526 LGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGP 2585 Query: 949 KGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMG------------SPGH 996 +G+ G GIPGD GS G+ G PG+ G KG +G MGP G KG G G Sbjct: 2586 QGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGE 2645 Query: 997 QGPPGSPGI---------PGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAM 1047 GPPG PG+ PG+P + + + + I + R F+ + Q + Sbjct: 2646 AGPPGRPGLAGHKGEMGEPGVPGQSGAPGK-EGLIGPKGDRGFDGQPGPKGDQGEKGERG 2704 Query: 1048 LAAQAYGRPGPPGKDGLPGPPGDPG------PQGYRGQKGERGEPGIGLPGSPGLPGTSA 1101 G PGP G DG GPPG PG P+G +GQKGERG PG + G+PG+PG A Sbjct: 2705 TPGIG-GFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPG--A 2761 Query: 1102 LGLPGSPGAPGPQGPPGPSG 1121 G G G PGP GP G G Sbjct: 2762 PGERGEQGRPGPAGPRGEKG 2781 Score = 605 bits (1561), Expect = e-173 Identities = 395/970 (40%), Positives = 468/970 (48%), Gaps = 147/970 (15%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P +Q + I KG+ G PG G G+KG +G PG G G PG G+ G +G EG Sbjct: 1464 PGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGP 1523 Query: 336 KGETGEKGEQGE---KGDPALAG--LNGENGLKGDLGPHGPPGPKGEKGDTGPPG--PPA 388 G TG +GE+GE GDPA+ G + G G KGD+GP GP G G +G+ GPPG P Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG 1583 Query: 389 LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKG 448 PG G G +GP G G+ G G +GPPG+ G PG PGPPG G G K ++G Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEG 1643 Query: 449 NDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE 508 GL G GE GL G PG GP G+KG+ G+P GE G G PG G +G +GE Sbjct: 1644 PPGDP--GLPGKAGERGLRGAPGVRGPVGEKGDQGDP---GEDGRNGSPGSSGPKGDRGE 1698 Query: 509 PGDPGPPGLIGSPG----LKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 PG PGPPG + G KG+ G G GPRGP GD GLP G PG++GI+G +G PG Sbjct: 1699 PGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLP---GAPGERGIEGFRGPPG 1755 Query: 565 GIIGPPGLPGP---KGEAGPPGKSLPGEPGLDGNPGAPGPRGPK---GERGLPGVHGSPG 618 G PG+ GP KG+ GPPG L G GLDG PGA GP GP G+ G PG G PG Sbjct: 1756 P-QGDPGVRGPAGEKGDRGPPG--LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPG 1812 Query: 619 DIGPQGI----GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPG 674 G QG+ G PG G G G+PG+ G G PG PG G G G G G+ G G Sbjct: 1813 LRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDG 1872 Query: 675 PPGDPIALPLLGDIGAL-LKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 P G+ A +LG G L G PG+ G +G GE G G+ G Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932 Query: 734 RGPPG-IPG-----------------------------------REGPKGSKGERGYPGI 757 RG PG +P R GPKG GE+G PG Sbjct: 1933 RGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGK 1992 Query: 758 PGEKGDEGLQGIPGIPGAPGPTGPPGL-MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPG 816 G G G +G+ G G PGP GPPGL +G G PGP+G GE G G PG PG G G Sbjct: 1993 EGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVG 2052 Query: 817 IPFNE-------RNGMSSLYKIKGGVNVPSYPGPPGPPGPK---GDPGP--VGEPGAMGL 864 G G +P PGPPGPPGPK +PGP GE G GL Sbjct: 2053 EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL 2112 Query: 865 PGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGP------PGVPGEPGERGPVGDIGFPGP 918 G +G PG GD+GP G G+ G+ G G PGP PG+PGE G GP G G GP Sbjct: 2113 KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGP 2172 Query: 919 EGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGD--------------------QGIP 958 GP G G +G G PGA G+ G G +GP G +G+ G P Sbjct: 2173 RGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP 2232 Query: 959 GDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEI 1018 G G G +G PGL G G G G PG G+ G G +G PG PG PG+P E Sbjct: 2233 GPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEP 2292 Query: 1019 KKYINQEVLRIFEERMAVFLSQLKLPAAM--------LAAQAYGRPGPPGKDGLPGP--- 1067 A + + LP A LA G PG G GLPGP Sbjct: 2293 ------------GPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGE 2340 Query: 1068 ---------PGDPGPQGYR---GQKGERGEPGIGLPGSPGLPGTSA----LGLPGSPGAP 1111 PGDPG G + G KG +G+PG+G+PGSPG PG LGLPG PGAP Sbjct: 2341 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP 2400 Query: 1112 GPQGPPGPSG 1121 G G PG +G Sbjct: 2401 GVVGFPGQTG 2410 Score = 598 bits (1541), Expect = e-170 Identities = 416/1075 (38%), Positives = 489/1075 (45%), Gaps = 278/1075 (25%) Query: 288 IPNK-GEAGLPGAPG---SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEG--------- 334 +P K GE GL GAPG G+KG +G+PGE+G +G+PG G KG++G G Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLV 1709 Query: 335 -------SKGETGEKGEQGE---KGDPALAGLNGENGLKGDLGPHGPPG------PKGEK 378 KGE G++G++G KGDP L G GE G++G GP GP G P GEK Sbjct: 1710 DTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEK 1769 Query: 379 GDTGPPG---PPALPGSLGIQGPQGP---------------PGKEGQRGRRGKTGPPGKP 420 GD GPPG L G G GP GP PG G++G G +GPPG P Sbjct: 1770 GDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLP 1829 Query: 421 GPPGPPGPPGIQGIHQTLGGYYNKDNKGND----------------EHEAGGLKGDKGET 464 G PG G PG+ G + G KG E A G+ G +G Sbjct: 1830 GKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPP 1889 Query: 465 GLPG-----------FPGSVGPKGQKGEPG---EPFTKGEKGDRGEPGVI---------- 500 GLPG PG GPKG +GE G E GE+G RGEPG + Sbjct: 1890 GLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETA 1949 Query: 501 --------------------------------GSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 G G +G PG GP G G GLKG +G Sbjct: 1950 GIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRG 2009 Query: 529 SAGSMGP-------RGPPGDVGLPGEHGIPG------------------KQGIKGEKGDP 563 G GP RGPPG GL GE G PG ++G +GEKG+ Sbjct: 2010 DPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGER 2069 Query: 564 G--GIIGPPGLPGPKGEAGPPGKSL---------------PGEPGLDGNPGAPGPRGPKG 606 G G GPPGLPG G GPPG + PG G G PG+ G +GPKG Sbjct: 2070 GEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKG 2129 Query: 607 ERGLPGVHGSPGDIGPQGI----GIPGRTGAQGPAGEPGIQGPRGLPGL------PGTPG 656 +RG+PG+ G G+ GP+G G+PG G GP G+PG+QGPRG PG PG PG Sbjct: 2130 DRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPG 2189 Query: 657 TPGNDGVPGRDGKPGLPGPPGD--PIALPLLGDIGAL-LKNFCGNC-----QASVPGLKS 708 PG G G G GL G PG+ P L G GA+ L G Q S PGL Sbjct: 2190 APGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS-PGLPG 2248 Query: 709 NKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQG 768 GE G G PG+ + + GD G G PG PG GP G KGE G G PG+ GL G Sbjct: 2249 QVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ-AVVGLPG 2307 Query: 769 IPGIPGAPGP-----TGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN 823 G GAPG G PG G G PGP G KGE G G PG PG G G P + Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG- 2366 Query: 824 GMSSLYKIKGGVNVPSYPGPPGPPGPKGD---PGPVGEPGAMGLPGLEG------FPGVK 874 +K GV VP PGPPGPPG KGD PG G PG +G PG G PG Sbjct: 2367 -----FKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPS 2421 Query: 875 GDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGD-----IGFPGPEGPSGKPGING 929 G+RG AGPPG G+ G G PGPPG G PG G GD +G PGP G G+PGI G Sbjct: 2422 GERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG 2481 Query: 930 KDGIPGAQG---IMGKPGDRGPKGERGDQGI----------------PGDRGSQG---ER 967 +DG PG +G + G PG RG +GE+GD G PG RG++G ER Sbjct: 2482 EDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGER 2541 Query: 968 GKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVL 1027 G GL G KG G G PG+KGS G PG +G G PG+ G+ Sbjct: 2542 GPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGL------------------- 2582 Query: 1028 RIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG 1087 L P A A G PG PGKDG+PG G+ G G+ G +G +GE G Sbjct: 2583 ----------LGPQGQPGA---AGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERG 2629 Query: 1088 I----------------GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 + G PG PGL G G G PG PG G PG G P+ Sbjct: 2630 VKGACGLDGEKGDKGEAGPPGRPGLAGHK--GEMGEPGVPGQSGAPGKEGLIGPK 2682 Score = 587 bits (1514), Expect = e-167 Identities = 401/1013 (39%), Positives = 460/1013 (45%), Gaps = 243/1013 (23%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KGE G PGA G PG G G PG PG PG KG G G +G+ GE+G +G KG+ Sbjct: 1295 KGERGFPGADGRPGSPGRAGNPG------TPGAPGLKGSPGLPGPRGDPGERGPRGPKGE 1348 Query: 351 PALAG--LNGEN----GLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 P G + GE G KGD GP GPPGP+G GD GP GPP LPG+ G Sbjct: 1349 PGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGT-------AMKGD 1401 Query: 405 EGQRGRRGKTGP------PGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLK 458 +G RG RG GP PG+PG PG PG PG QG +G K KG+ E A GL Sbjct: 1402 KGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQG---PVGPPGKKGEKGDSEDGAPGLP 1458 Query: 459 GDKG---ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS------------- 502 G G E G G PG++GPKG +G PG GEKG+RG PG GS Sbjct: 1459 GQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAK 1518 Query: 503 -----------QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIP 551 QG KGEPG PG P ++G P + G +G G +GP GP G G+ GE G P Sbjct: 1519 GPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGPKGEKGDVGPAGPRGATGVQGERGPP 1577 Query: 552 GK--QGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERG 609 G G G KGDPG GP GL G AGPPG S G PG G+PG PGP GP G RG Sbjct: 1578 GLVLPGDPGPKGDPGDR-GPIGLTG---RAGPPGDS--GPPGEKGDPGRPGPPGPVGPRG 1631 Query: 610 LPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDG 668 G G GD GP G G+PG+ G +G G PG++GP G G G PG G +G PG G Sbjct: 1632 RDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSG 1691 Query: 669 KPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARK 728 G G PG P G G L+ G + PG + +G G G+PG + + Sbjct: 1692 PKGDRGEPGPP------GPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGER 1745 Query: 729 GDIGPRGPPGI---PGREGPKGSKGERGYPGI---------------------------- 757 G G RGPPG PG GP G KG+RG PG+ Sbjct: 1746 GIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP 1805 Query: 758 -----PGEKGDEGL---QGIPGIPGAPGPTGPPGLMGRTGHPGP------------TGAK 797 PG +G++GL G PG+PG PG G PGL G+ G PG +GA Sbjct: 1806 GRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGAS 1865 Query: 798 GEKGSDGP------PGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPS--YPGPPGPPGP 849 G +G DGP PG GP GPPG+P G V P +PG PG GP Sbjct: 1866 GREGRDGPKGERGAPGILGPQGPPGLP--------------GPVGPPGQGFPGVPGGTGP 1911 Query: 850 KGDPGPVGEPGAMGLPG---LEGFPGV--------------------------------- 873 KGD G G G GLPG L G PG Sbjct: 1912 KGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFL 1971 Query: 874 ---------KGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVG-DIGFPGPEGPSG 923 KGD G GPPG G G PG G G G+PG +GP G +G GP GPSG Sbjct: 1972 PVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSG 2031 Query: 924 KPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGP-- 981 G GK GIPG G G G+ G GERG++G G+RG QG G PGL G G GP Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091 Query: 982 ---------------MGPPGNKGSMGSPGH---QGPPGSPGIPGIPADAVSFEEIKKYIN 1023 GPPG KG+ G PG QGP G G+PGI D + N Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGN 2151 Query: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGER 1083 LP G GP GK GL GP G PGP G G G Sbjct: 2152 PG-----------------LPGER------GMAGPEGKPGLQGPRGPPGPVGGHGDPGPP 2188 Query: 1084 GEPGI----------GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 G PG+ GL G PG G GL G GA G GPPGPSG P+ Sbjct: 2189 GAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQ 2241 Score = 584 bits (1505), Expect = e-166 Identities = 387/976 (39%), Positives = 455/976 (46%), Gaps = 213/976 (21%) Query: 292 GEAGLPG---APGS---------------PGQKGHKGEPGENGLHGAPGFPGQKGEQGFE 333 G+ GLPG APG PG G G PG G G PG PG KG G Sbjct: 1272 GDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLP 1331 Query: 334 GSKGETGEKGEQGEKGDPALAG--LNGEN----GLKGDLGPHGPPGPKGEKGDTGPPGPP 387 G +G+ GE+G +G KG+P G + GE G KGD GP GPPGP+G GD GP GPP Sbjct: 1332 GPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPP 1391 Query: 388 ALPGSLGIQGPQGPPGKEGQRGRRGKTGP------PGKPGPPGPPGPPGIQGIHQTLGGY 441 LPG+ G +G RG RG GP PG+PG PG PG PG QG +G Sbjct: 1392 GLPGT-------AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQG---PVGPP 1441 Query: 442 YNKDNKGNDEHEAGGL---KGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPG 498 K KG+ E A GL G GE G G PG++GPKG +G PG GEKG+RG PG Sbjct: 1442 GKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPG 1501 Query: 499 VIGS------------------------QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG 534 GS QG KGEPG PG P ++G P + G +G G +G Sbjct: 1502 PAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG-PAVAGPKGEKGDVG 1560 Query: 535 PRGPPGDVGLPGEHGIPG--KQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGL 592 P GP G G+ GE G PG G G KGDPG GP GL G AGPPG S G PG Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD-RGPIGL---TGRAGPPGDS--GPPGE 1614 Query: 593 DGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGL 651 G+PG PGP GP G RG G G GD GP G G+PG+ G +G G PG++GP G G Sbjct: 1615 KGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGD 1674 Query: 652 PGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKG 711 G PG G +G PG G G G PG P G G L+ G + PG + +G Sbjct: 1675 QGDPGEDGRNGSPGSSGPKGDRGEPGPP------GPPGRLVDTGPGAREKGEPGDRGQEG 1728 Query: 712 EEGGAGEPGKYDSMARKGDIGPRGPP---GIPGREGPKGSKGERGYPGIPGEKGDEGLQG 768 G G+PG + +G G RGPP G PG GP G KG+RG PG+ +G G Sbjct: 1729 PRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGL------DGRSG 1782 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSL 828 + G PGA GP+GP G G+ G PG G G +G G PG GPPG PG P Sbjct: 1783 LDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKP---------- 1832 Query: 829 YKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGM 888 G P G G PG G+ G GE G G G EG G KG+R G PGI G Sbjct: 1833 ----GEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGER---GAPGILGP 1885 Query: 889 SGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD--- 945 G PG PGP G PG+ G G G GP+G G+ G G+ G+PG +G+ G+PG Sbjct: 1886 QGPPGLPGPVGPPGQ----GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPN 1941 Query: 946 ------------------------------------RGPKGERGDQGIPGDRGSQGERGK 969 RGPKG+ G+QG PG G G G+ Sbjct: 1942 VDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGE 2001 Query: 970 PGLTGMKGAIGPMGPP----GNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQE 1025 GL G +G GP GPP G +G G G G PG PGIPG+P A E + + Sbjct: 2002 RGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERG 2061 Query: 1026 VLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQ----------- 1074 ER GR GPPG G PGPPG PGP+ Sbjct: 2062 ERGEKGER-----------------GEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104 Query: 1075 ------------------GYRGQKGERGEPGI----------GLPGSPGLPGTSALGLP- 1105 G +G KG+RG PGI G G+PGLPG + P Sbjct: 2105 GEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE 2164 Query: 1106 GSPGAPGPQGPPGPSG 1121 G PG GP+GPPGP G Sbjct: 2165 GKPGLQGPRGPPGPVG 2180 Score = 571 bits (1472), Expect = e-162 Identities = 393/1027 (38%), Positives = 460/1027 (44%), Gaps = 231/1027 (22%) Query: 291 KGEAGLPGAPGSP--------GQKGHKGEPGENGLHGA--------------PGFPGQKG 328 +GE G PG PG P G KG KG+ G G GA PG PG KG Sbjct: 1530 QGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKG 1589 Query: 329 EQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPA 388 + G G G TG G G+ G P G G G G +GP G G GEKGD GPPG P Sbjct: 1590 DPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPG 1649 Query: 389 LPGSLG---------IQGP------QGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQG 433 LPG G ++GP QG PG++G+ G G +GP G G PGPPGPPG Sbjct: 1650 LPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG--R 1707 Query: 434 IHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVG------PKGQKGEPGEPFT 487 + T G K G+ E G +G KG+ GLPG PG G P G +G+PG Sbjct: 1708 LVDTGPGAREKGEPGDRGQE--GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGP 1765 Query: 488 KGEKGDRGEPGVIGSQGVKGEPGDPGP------------PGLIGSPGLKGQQGSAGSMGP 535 GEKGDRG PG+ G G+ G+PG GP PG G PGL+G+QG G GP Sbjct: 1766 AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825 Query: 536 RG---PPGDVGLPG------EHGIPGKQGIKGEKGDPG-----------------GIIGP 569 G PG+ G PG E G PG+ G KGEKGD G GI+GP Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGP 1885 Query: 570 PGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPG---VHGSPGDI------ 620 G PG G GPPG+ PG PG G G G G KGE+GLPG + G PG + Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL 1945 Query: 621 ---------------------------------GPQG-------------IGIPGRTGAQ 634 GP+G IG PG G + Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLK 2005 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKN 694 G G+PG QGP GL G G PG G+ G GKPG+PG PG G +G Sbjct: 2006 GDRGDPGPQGPPGLA--LGERGPPGPSGLAGEPGKPGIPGLPGRA------GGVG----- 2052 Query: 695 FCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG-----------IPGRE 743 +A PG + +GE+G GE G+ G GP GPPG + G + Sbjct: 2053 -----EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQ 2107 Query: 744 GPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP------PGLMGRTGHPGPTGAK 797 GP G KG +G PG G++G +G +G+PGI G G GP PGL G G GP G Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKP 2167 Query: 798 GEKGSDGPPGK------PGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG 851 G +G GPPG PGPPG PG+ S K + G P G GP G G Sbjct: 2168 GLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVG 2227 Query: 852 DPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVG 911 PGP G G +G G G PG G+ G G PG G SGK G G PGVPG PG GPVG Sbjct: 2228 LPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG 2287 Query: 912 DIGFPGPEGPSGK-----PGINGKDGIPG-----------AQGIMGKPGDRGPKGERGDQ 955 G PGP G G+ PG G+ G PG A+G G PG RG KGE G Sbjct: 2288 PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRA 2347 Query: 956 GIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSF 1015 G PGD G G++G PG G KG G +G PG+ G G PG +G G PG+PG P V F Sbjct: 2348 GEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPG-VVGF 2405 Query: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PG 1072 P G+PGP G+ GL GPPG PG Sbjct: 2406 ----------------------------PGQTGPRGEMGQPGPSGERGLAGPPGREGIPG 2437 Query: 1073 PQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 P G G G G PG GL G G PG G G G PG +G G G+ P P Sbjct: 2438 PLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGP 2497 Query: 1132 VSHAHQR 1138 +R Sbjct: 2498 PGSRGER 2504 Score = 559 bits (1441), Expect = e-159 Identities = 348/818 (42%), Positives = 416/818 (50%), Gaps = 114/818 (13%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 GEAG PG G G+KG +GE G +G G PG PG G G + S E G G GE+G P Sbjct: 2052 GEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP-GLSGEQGPP 2110 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP------PALPGSLGIQGPQGPPGKE 405 L G GE G GD GP G G G KGD G PGP P LPG G+ GP+G PG + Sbjct: 2111 GLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQ 2170 Query: 406 GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETG 465 G RG GP G G PGPPG PG+ G G K G GL G G G Sbjct: 2171 GPRG---PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVG 2227 Query: 466 LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKG 525 LPG PG G G +G PG P G+ G+ G+PG G G G+ GD G PG+ GSPGL G Sbjct: 2228 LPGPPGPSGLVGPQGSPGLP---GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284 Query: 526 QQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGI----IGPPG------LPGP 575 +GP+G PG G PG+ + G G KGEKG PGG+ +G PG LPGP Sbjct: 2285 P------VGPKGEPGPTGAPGQ-AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGP 2337 Query: 576 KGEAGPPGKS-LPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI----GIPGR 630 +GE G G++ PG+PG DG GAPGP+G KG+ G+ GV GSPG GP G+ G+PG Sbjct: 2338 RGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGV-GVPGSPGPPGPPGVKGDLGLPGL 2396 Query: 631 TGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGA 690 GA G G PG GPRG G PG G G G PGR+G PG GPPG P ++ G G Sbjct: 2397 PGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASG- 2455 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 LK G+ +PG + +GE G GE G R G GPRG G PG G +G KG Sbjct: 2456 -LKGDKGDPGVGLPGPRGERGEPGIRGEDG------RPGQEGPRGLTGPPGSRGERGEKG 2508 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG 810 + G G+ G+KGD + I G PGP G G MG G G G KG +G +G PG G Sbjct: 2509 DVGSAGLKGDKGDSAV-----ILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563 Query: 811 PPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGF 870 G PG KG +P G G GP+G PG G PG G PG +G Sbjct: 2564 SKGEPGD--------------KGSAGLP---GLRGLLGPQGQPGAAGIPGDPGSPGKDGV 2606 Query: 871 PGVKGDRGPAG---PPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI 927 PG++G++G G P G+ G G GA G G G+ GE GP G G G +G G+PG+ Sbjct: 2607 PGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGV 2666 Query: 928 NGKDGIPGAQGIMGKPGDR---GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP 984 G+ G PG +G++G GDR G G +GDQG G+RG+ G G PG +G G+ GP GP Sbjct: 2667 PGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGP 2726 Query: 985 PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLP 1044 PG+ G G G QG G G PG ER+ Sbjct: 2727 PGSVGPRGPEGLQGQKGERGPPG------------------------ERVV--------- 2753 Query: 1045 AAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGE 1082 G PG PG G G G PGP G RG+KGE Sbjct: 2754 ---------GAPGVPGAPGERGEQGRPGPAGPRGEKGE 2782 Score = 514 bits (1324), Expect = e-145 Identities = 326/769 (42%), Positives = 392/769 (50%), Gaps = 109/769 (14%) Query: 295 GLPGAPGSPGQKGHKGEPGENGLHGAPG---FPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 GL G G PG KG KGEPG NG G G PG KG++G G +G+ G G GE+G Sbjct: 2102 GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERG-- 2159 Query: 352 ALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG-- 409 +AG G+ GL+ GP GPPGP G GD GPPG P L G G QGP G G+ G+ G Sbjct: 2160 -MAGPEGKPGLQ---GPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPP 2215 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 RG TGP G G PGPPGP G+ G + GL G GETG PG Sbjct: 2216 GRGLTGPTGAVGLPGPPGPSGLVG-----------------PQGSPGLPGQVGETGKPGA 2258 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPG--LIGSPGLKGQQ 527 PG G G+ G+ G P G G PG+ G G KGEPG G PG ++G PG KG++ Sbjct: 2259 PGRDGASGKDGDRGSP------GVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312 Query: 528 GSAGSM-----GPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPP 582 G+ G + G G GD GLPG G G+ G GE GDPG G G PGPKG G P Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGE-DGQKGAPGPKGFKGDP 2371 Query: 583 GKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGI 642 G +P G+PG PGP G KG+ GLPG+ G+PG +G PG+TG +G G+PG Sbjct: 2372 GVGVP------GSPGPPGPPGVKGDLGLPGLPGAPG-----VVGFPGQTGPRGEMGQPGP 2420 Query: 643 QGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQAS 702 G RGL G PG G PG G PG G G PG G LK G+ Sbjct: 2421 SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASG--------------LKGDKGDPGVG 2466 Query: 703 VPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKG 762 +PG + +GE G GE G R G GPRG G PG G +G KG+ G G+ G+KG Sbjct: 2467 LPGPRGERGEPGIRGEDG------RPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520 Query: 763 DEG-LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE 821 D + G PG GA G G G G G GP G G+ G G G+PG G G+P Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP--- 2577 Query: 822 RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEP---GAMGLPGLEGFPGVK---- 874 G+ L +G PG PG PG G PG GE G MG GL+G GVK Sbjct: 2578 --GLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACG 2635 Query: 875 -----GDRGPAGPPGIAGMS------GKPGAPGPPGVPGEPGERGPVGDIGF---PGPEG 920 GD+G AGPPG G++ G+PG PG G PG+ G GP GD GF PGP+G Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695 Query: 921 PSGKPGINGKDGI---PGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKG 977 G+ G G GI PG G G G GP G G +G G +G +GERG PG + G Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG-ERVVG 2754 Query: 978 AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEV 1026 A G G PG +G G PG GP G G A++ ++I+ ++ QE+ Sbjct: 2755 APGVPGAPGERGEQGRPGPAGPRGEKG-----EAALTEDDIRGFVRQEM 2798 Score = 502 bits (1292), Expect = e-142 Identities = 350/855 (40%), Positives = 401/855 (46%), Gaps = 188/855 (21%) Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVI 500 Y K KG E GL+G G G PG PG G G +G PG KGE+G G G Sbjct: 1250 YCPKGQKG--EPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRP 1307 Query: 501 GSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGE------HGIPGKQ 554 GS G G PG PG PGL GSPGL G +G G GPRGP G+ G PG+ G+PG++ Sbjct: 1308 GSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRK 1367 Query: 555 GIKGEKGDPG--------GIIGPPGLPGP--------KGEAGPPGKS----LPGEPGLDG 594 G G G PG G GPPGLPG +GE GPPG PGEPGL G Sbjct: 1368 GDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPG 1427 Query: 595 NPGAPGPRGP------KGERG--------LPGVHGSPGDIGPQG----IGIPGRTGAQGP 636 PG+PGP+GP KGE+G LPG GSPG+ GP+G IG G G GP Sbjct: 1428 LPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGP 1487 Query: 637 AGE---------PGIQGPRGLPGLPGTPGTPGNDGVPG---RDGKPGLPGPPGDPIAL-P 683 GE PG G RGLPG+ G PG G +G PG R G+ G PG PGDP + P Sbjct: 1488 LGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP 1547 Query: 684 LL-------GDIGALLKNFCGNCQAS-------VPGLKSNKGEEGGAGEPGKYDSMARKG 729 + GD+G Q +PG KG+ G G G G Sbjct: 1548 AVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPG 1607 Query: 730 DIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPG---------APGPTG 780 D GP G G PGR GP G G RG G GEKGDEG G PG+PG APG G Sbjct: 1608 DSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG 1667 Query: 781 PPGLMGRTGHPGPTGAKGEKGSDGPPG---KPGPPGPPGIPFNERNGMSSLYKIKGGVNV 837 P G G G PG G G GS GP G +PGPPGPPG + G KG Sbjct: 1668 PVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGARE----KGE--- 1720 Query: 838 PSYPGPPGPPGPKGDPGPVGEPGAMGL------PGLEGFPGV------KGDRGPAGPPGI 885 P G GP GPKGDPG G PG G+ PG +G PGV KGDRGP G G Sbjct: 1721 PGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGR 1780 Query: 886 AGMSGKPGAPGPPGV---------PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA 936 +G+ GKPGA GP G PG G G G+ G PGP GP G PG G+DG PG Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGL 1840 Query: 937 QGIMGKPGDRGP---KGERGDQGIPGDR---GSQGERGKPGLTGMK---GAIGPMGPP-- 985 G G+PGD G KGE+GD G G G +GERG PG+ G + G GP+GPP Sbjct: 1841 NGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQ 1900 Query: 986 ------------GNKGSMGSPGHQGPPGSPGIPGIPADAVSFEE------IKKYINQEVL 1027 G++G GS G QG PG G+ G P + + IK +E++ Sbjct: 1901 GFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIV 1960 Query: 1028 RIFEERMAVFLSQLKLPAAMLAAQA-YGRPGPPGKD---------GLPGPPGDPGPQGYR 1077 ++E F L +P + G GPPGK+ GL G GDPGPQG Sbjct: 1961 ETWDESSGSF---LPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPP 2017 Query: 1078 G-QKGERGEPG-IGLPGSPGLPGTSAL-------------------------------GL 1104 G GERG PG GL G PG PG L G Sbjct: 2018 GLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077 Query: 1105 PGSPGAPGPQGPPGP 1119 PG PG PGP GPPGP Sbjct: 2078 PGLPGTPGPPGPPGP 2092 Score = 492 bits (1266), Expect = e-139 Identities = 313/730 (42%), Positives = 366/730 (50%), Gaps = 99/730 (13%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 + G+ G G G PG KG +GEPG G G PG PG++G G EG G G +G G G Sbjct: 2121 SNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVG 2180 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRG 409 G G GL G GP GP G KGE G+TGPPG L G G G GPPG G G Sbjct: 2181 GHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVG 2239 Query: 410 RRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGF 469 +G G PG+ G G PG PG G A G GD+G G+PG Sbjct: 2240 PQGSPGLPGQVGETGKPGAPGRDG--------------------ASGKDGDRGSPGVPGS 2279 Query: 470 PGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPG--PPGLIGSPGLKGQQ 527 PG GP G KGEPG G+ V+G G KGE G PG L+G PG KG + Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQ-------AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDR 2332 Query: 528 GSAGSMGPRGPPGDVGLPGEHGIPGKQGI---KGEKGDPG----GIIGPPGLPGPKGEAG 580 G G G +G G G PG+ G G++G KG KGDPG G GPPG PG KG+ G Sbjct: 2333 GLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLG 2392 Query: 581 PPGKSLPGEPGLDGNPGAPGPR------GPKGERGL---PGVHGSPGDIGPQG----IGI 627 PG LPG PG+ G PG GPR GP GERGL PG G PG +GP G +G Sbjct: 2393 LPG--LPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGP 2450 Query: 628 PGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGD 687 PG +G +G G+PG+ G G G G PG G DG PG++G GL GPPG GD Sbjct: 2451 PGASGLKGDKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGD 2509 Query: 688 IGALLKNFCGNCQASVPGLKSNKGEEGG-AGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 +G+ GLK +KG+ G PG KGD+G RGP G+ G +GP+ Sbjct: 2510 VGS-------------AGLKGDKGDSAVILGPPG---PRGAKGDMGERGPRGLDGDKGPR 2553 Query: 747 GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPP 806 G G+ G G GE GD+G G+PG+ G GP G PG G G PG G G G G Sbjct: 2554 GDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEK 2613 Query: 807 GKPGPPGPPGIPFNER--NGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGL 864 G G GP G+ ER G L KG PG PG G KG+ G G PG G Sbjct: 2614 GDVGFMGPRGLK-GERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA 2672 Query: 865 PGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGP---EGP 921 PG EG G KGDR G G PGP G GE GERG G GFPGP +G Sbjct: 2673 PGKEGLIGPKGDR------------GFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGS 2720 Query: 922 SGKPGINGKDGIPGAQGIMGKPGDRGPKGER--GDQGIPGDRGSQGERGKPGLTGMKGAI 979 +G PG G G G +G+ G+ G+RGP GER G G+PG G +GE+G+P Sbjct: 2721 AGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRP--------- 2771 Query: 980 GPMGPPGNKG 989 GP GP G KG Sbjct: 2772 GPAGPRGEKG 2781 Score = 422 bits (1084), Expect = e-117 Identities = 279/706 (39%), Positives = 323/706 (45%), Gaps = 132/706 (18%) Query: 503 QGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDV------GLPGEHGIPGKQGI 556 +G KGEPG+ G G +G PG G G G+ GP+GPPG G PG G PG G Sbjct: 1253 KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGR 1312 Query: 557 KGEKGDPG--GIIGPPGLPGP------------KGEAGPPGKSL----PGEPGLDGNPGA 598 G G PG G+ G PGLPGP KGE G PG+ + PG PG G+PG Sbjct: 1313 AGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGP 1372 Query: 599 PGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAG--EPGIQ-GPRGLPGLPGTP 655 GP GP+G G PG G PG G G G G +GP G E GI G GLPGLPG+P Sbjct: 1373 SGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSP 1432 Query: 656 GTPGNDGVPGR--------DGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLK 707 G G G PG+ DG PGLPG PG P G GA+ G K Sbjct: 1433 GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI-------------GPK 1479 Query: 708 SNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQ 767 ++G G GE G+ G G RG PG+ GR G KG +G G G GEKG+ G Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539 Query: 768 GIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGK--PGPPGPPGIPFNE---- 821 G P + G P GP G G G GP GA G +G GPPG PG PGP G P + Sbjct: 1540 GDPAVVG-PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIG 1598 Query: 822 ---RNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG 878 R G G P PGPPGP GP+G G VGE G G PG G PG G+RG Sbjct: 1599 LTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERG 1658 Query: 879 PAGPPGIAGMSGKPGAPGPPGVPGE---PGERGPVGDIGFPGPEGPSGK----------- 924 G PG+ G G+ G G PG G PG GP GD G PGP GP G+ Sbjct: 1659 LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREK 1718 Query: 925 --PGINGKDG---------IPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLT 973 PG G++G +PGA G G G RGP G +GD G+ G G +G+RG PGL Sbjct: 1719 GEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLD 1778 Query: 974 GMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 G G G G G G G+ G G PG G+PG+ + Sbjct: 1779 GRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQ--------------------- 1817 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPG 1092 G PGP G GLPG PG+ G G G+ GE G+PG G G Sbjct: 1818 --------------------GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857 Query: 1093 SPGLPGTSAL-------GLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 G G S G G+PG GPQGPPG G P +P Sbjct: 1858 EKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP 1903 Score = 317 bits (811), Expect = 5e-86 Identities = 189/466 (40%), Positives = 236/466 (50%), Gaps = 41/466 (8%) Query: 252 EQDGFGNIASSWVTAHASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGE 311 E+ G +A V +K LP + K + G+ G G G+PG KG KG+ Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370 Query: 312 --------------PGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGLN 357 PG G G PG PG G GF G G GE G+ G G+ LAG Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430 Query: 358 GENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPP 417 G G+ G LGP GPPG G G +G G PG +G+ GP+G G+ G RG G+ G Sbjct: 2431 GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG-VGLPGPRGERGEPGIRGEDGRPGQE 2489 Query: 418 GKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-----GLKGDKGETGLPGFPGS 472 G G GPPG G +G +G K +KG+ G G KGD GE G G G Sbjct: 2490 GPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGD 2549 Query: 473 VGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGE---------PGDPGPPGLIGSPGL 523 GP+G G+PG+ +KGE GD+G G+ G +G+ G PGDPG PG G PG+ Sbjct: 2550 KGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGI 2609 Query: 524 KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--------GIIGPPGLPGP 575 +G++G G MGPRG G+ G+ G G+ G++G KGE G PG G +G PG+PG Sbjct: 2610 RGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQ 2669 Query: 576 KGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGA 633 G G G P G+ G DG PG G +G KGERG PG+ G PG G G G PG G+ Sbjct: 2670 SGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGS 2729 Query: 634 QGPAGEPGIQGPRGLPGLPG--TPGTPGNDGVPGRDGKPGLPGPPG 677 GP G G+QG +G G PG G PG G PG G+ G PGP G Sbjct: 2730 VGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAG 2775 Score = 281 bits (718), Expect = 3e-75 Identities = 176/450 (39%), Positives = 212/450 (47%), Gaps = 80/450 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHG-----------------------APGFPGQK 327 KGEAG G PG PG+ G KG PG G G PG PG Sbjct: 2341 KGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAP 2400 Query: 328 GEQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPP 387 G GF G G GE G+ G G+ LAG G G+ G LGP GPPG G G +G G Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDK 2460 Query: 388 ALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNK 447 PG +G+ GP+G G+ G RG G+ G G G GPPG G +G +G K +K Sbjct: 2461 GDPG-VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDK 2519 Query: 448 GNDEHEAG-----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS 502 G+ G G KGD GE G G G GP+G G+PG+ +KGE GD+G G+ G Sbjct: 2520 GDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGL 2579 Query: 503 QGVKGE---------PGDPGPPGLIGSPGLKGQQGSAGSMGPRG---------------- 537 +G+ G PGDPG PG G PG++G++G G MGPRG Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGE 2639 Query: 538 --------PPG------------DVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGP 575 PPG + G+PG+ G PGK+G+ G KGD G G GP G G Sbjct: 2640 KGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE 2699 Query: 576 KGEAGPPG-KSLPGEPGLDGNPGAPGP---RGPKGERGLPGVHGSPGDIGPQGIGIPGRT 631 KGE G PG PG G DG+ G PGP GP+G GL G G G G + +G PG Sbjct: 2700 KGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVP 2759 Query: 632 GAQGPAGEPGIQGPRGLPGLPGTPGTPGND 661 GA G GE G GP G G G +D Sbjct: 2760 GAPGERGEQGRPGPAGPRGEKGEAALTEDD 2789 Score = 191 bits (486), Expect = 3e-48 Identities = 118/292 (40%), Positives = 143/292 (48%), Gaps = 68/292 (23%) Query: 849 PKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERG 908 P+ +P PV P G +G PG G RG GPPG G+ G+ GAPGP G PG +G Sbjct: 1242 PRPEPCPVYCP-----KGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKG 1296 Query: 909 PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERG 968 + GFPG +G G PG G G PGA G+ G PG GP+G+ G++G G +G G G Sbjct: 1297 ---ERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPG 1353 Query: 969 K------PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPG--IPGIPADAVSFEEIKK 1020 + PGL G KG GP GPPG +G +G PG +GPPG PG + G D Sbjct: 1354 QVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDR-------- 1405 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGP------PGKDGLPGPPGDPGPQ 1074 ER G PGP PG+ GLPG PG PGPQ Sbjct: 1406 ----------GER--------------------GPPGPGEGGIAPGEPGLPGLPGSPGPQ 1435 Query: 1075 GYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 G G G++GE G G+PGLPG PG+PG QGP GP G P+ Sbjct: 1436 GPVGPPGKKGEKGDSEDGAPGLPG--------QPGSPGEQGPRGPPGAIGPK 1479 Score = 186 bits (473), Expect = 8e-47 Identities = 120/314 (38%), Positives = 141/314 (44%), Gaps = 40/314 (12%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGF---------PGQKGEQGFEGSKGETGEK 342 G+ G G G PG KG KGEPG+ G G PG PG G G GS G+ G Sbjct: 2548 GDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVP 2607 Query: 343 GEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPP 402 G +GEKGD G G G +G G G G KG+KG+ GPPG P L G G G G P Sbjct: 2608 GIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVP 2667 Query: 403 GKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKG 462 G+ G G+ G GP G G G PGP G Q G+KG Sbjct: 2668 GQSGAPGKEGLIGPKGDRGFDGQPGPKGDQ--------------------------GEKG 2701 Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD--PGPPGLIGS 520 E G PG G GP G G G P G G RG G+ G +G +G PG+ G PG+ G+ Sbjct: 2702 ERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGA 2761 Query: 521 PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPG--KQGIKGEKGDPGGIIGPPGLPGPKGE 578 PG +G+QG G GPRG G+ L E I G +Q + G I P P Sbjct: 2762 PGERGEQGRPGPAGPRGEKGEAALT-EDDIRGFVRQEMSQHCACQGQFIASGSRPLPSYA 2820 Query: 579 AGPPGKSLPGEPGL 592 A G L P L Sbjct: 2821 ADTAGSQLHAVPVL 2834 Score = 131 bits (329), Expect = 4e-30 Identities = 80/215 (37%), Positives = 100/215 (46%), Gaps = 64/215 (29%) Query: 275 LPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQ------KG 328 L ++ +K C KG+ G G PG PG GHKGE GE G+ G G PG+ KG Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG 2683 Query: 329 EQGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPA 388 ++GF+G G G++GE+GE+G P + G PGP G G GPPGPP Sbjct: 2684 DRGFDGQPGPKGDQGEKGERGTPGIGGF---------------PGPSGNDGSAGPPGPP- 2727 Query: 389 LPGSLGIQGPQGPPGKEGQRGRRGKTGPPGK--PGPPGPPGPPGIQGIHQTLGGYYNKDN 446 G GP+GP G +GQ+G R GPPG+ G PG PG P Sbjct: 2728 -----GSVGPRGPEGLQGQKGER---GPPGERVVGAPGVPGAP----------------- 2762 Query: 447 KGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGE 481 GE G G PG GP+G+KGE Sbjct: 2763 ---------------GERGEQGRPGPAGPRGEKGE 2782 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 605 bits (1561), Expect = e-173 Identities = 372/903 (41%), Positives = 434/903 (48%), Gaps = 113/903 (12%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G+ G G PG PG++G G G GL G G PG KG +GF G G G+ G G KG+P Sbjct: 230 GDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEP 289 Query: 352 ALAGLNGE------NGLKGDLGPHGPPGPKGEKGD------------TGPPGPPALPGSL 393 G NG GL G+ G G PGP G +G+ TGP GPP PG++ Sbjct: 290 GSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAV 349 Query: 394 GIQG---PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGND 450 G +G PQGP G EG +G RG+ GPPG G GP G PG G Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADG----------------- 392 Query: 451 EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 + A G G G G PGFPG+ GP G +G G P KG G+ G PG G G KGEPG Sbjct: 393 QPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPG 452 Query: 511 D---PGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGII 567 GPPG G G +G +G G G GPPG+ G PG G PG G+ G KG P G Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKG-PAGER 511 Query: 568 GPPGLPGPKG---EAGPPGKS-LPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623 G PG GPKG EAG PG++ LPG GL G+PG+PGP G G G G G PG GP Sbjct: 512 GSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPP 571 Query: 624 GI----GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDP 679 G G+ G G +G AGEPG G RG+PG PG G G DG G G PG GP G+ Sbjct: 572 GARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631 Query: 680 IALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGI 739 G G + G A PG GE+G G+ G +G+ G G G+ Sbjct: 632 GEQGPAGSPG--FQGLPG--PAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGV 687 Query: 740 PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE 799 G GP G +G G PG G KGD G G PG GAPG G PG G G PGP KG+ Sbjct: 688 QGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGP---KGD 744 Query: 800 KGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEP 859 +G GP G G PG G+ G++ GP GPPGP G PG GE Sbjct: 745 RGDAGPKGADGSPGKDGV-----RGLT---------------GPIGPPGPAGAPGDKGES 784 Query: 860 GAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE 919 G G G G G GDRG GPPG AG +G PGA G PG GEPG+ G GD G PGP Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844 Query: 920 GPSGKPGINGKDGIPGAQGIMG---------------KPGDRGPKGERGDQGIPGDRGSQ 964 GP+G PG G G PGA+G G + G GP G G G PG G + Sbjct: 845 GPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKE 904 Query: 965 G---ERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKY 1021 G RG+ G G G +GP GPPG G GSPG GP G+PG PG P + Sbjct: 905 GGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG-PQGIAGQRGVVGL 963 Query: 1022 INQEVLRIF-----------EERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD 1070 Q R F ++ + + P M G PG G++G PG G Sbjct: 964 PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 1071 PGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCL 1129 PG G G KG+RGE G G PG+PG PG PG G G G G +G P + Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGA-----PGPVGPAGKSGDRGETGPAGPAGPV 1078 Query: 1130 YPV 1132 PV Sbjct: 1079 GPV 1081 Score = 604 bits (1558), Expect = e-172 Identities = 375/893 (41%), Positives = 432/893 (48%), Gaps = 104/893 (11%) Query: 292 GEAGLPGAPGSPGQKGH------KGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQ 345 G AG PG PG+ G KG +G G G+ G PG PG G G G+ G G+ G + Sbjct: 338 GPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL---------PGSLGIQ 396 G G P +AG G G +G GP GP GP G KG++G PG P PG +G+Q Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQ 457 Query: 397 GPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGG 456 GP GP G+EG+RG RG+ GP G PGPPG G PG +G A G Sbjct: 458 GPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGF-----------------PGADG 500 Query: 457 LKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPG 516 + G KG G G PG GPKG GE G P GE G+ G++G+ G PG PGP G Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRP---------GEAGLPGAKGLTGSPGSPGPDG 551 Query: 517 LIGSPGLKGQQGSAGSMGP---RGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPG 571 G PG GQ G G GP RG G +G PG G G+ G GE+G PG G +GP G Sbjct: 552 KTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAG 611 Query: 572 LPGPKGEAGPPGKSLP----GEPGLDGNP---GAPGPRGPKGERGLPGVHGSPGDIGPQG 624 G G GPPG + P GE G G+P G PGP GP GE G PG G PGD+G G Sbjct: 612 KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG 671 Query: 625 IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPL 684 G G +G GE G+QGP G G G G PGNDG G G PG PG G P + Sbjct: 672 PS--GARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM 729 Query: 685 LGDIGALLKNFCGNCQASVPGLKSNKGE---EGGAGEPGKYDSMARKGDIGPRGPPGIPG 741 G+ GA A +PG K ++G+ +G G PGK G IGP GP G PG Sbjct: 730 PGERGA----------AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPG 779 Query: 742 REGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKG 801 +G G G G G G GD G G PG G GP G G G G PG GAKG+ G Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839 Query: 802 SDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD------PG 854 GP G GPPGP G + G G P G GPPGP G+ PG Sbjct: 840 PPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPG 899 Query: 855 PVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEP------GERG 908 P G+ G G G G G G+ GP GPPG AG G PGA GP G PG P G+RG Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959 Query: 909 PV------GDIGFPGPEGPSGKPGINGKDGIPGAQ---GIMGKPGDRGPKGERGDQGIPG 959 V G+ GFPG GPSG+PG G G G + G MG PG GP GE G +G PG Sbjct: 960 VVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPG 1019 Query: 960 DRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGI-----PGIPADAVS 1014 GS G G PG G +G GP GPPG G+ G+PG GP G G P PA V Sbjct: 1020 AEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG 1079 Query: 1015 FEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQ 1074 + + R ++ + + G PGPPG G GP G GP Sbjct: 1080 PVGARGPAGPQGPR-GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPA 1138 Query: 1075 GYRGQKGERGEPG----IGLPGSPGLPG----TSALGLPGSPGAPGPQGPPGP 1119 G RG G G PG GLPG G PG T G G PG PGP GPPGP Sbjct: 1139 GPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGP 1191 Score = 599 bits (1544), Expect = e-171 Identities = 380/921 (41%), Positives = 428/921 (46%), Gaps = 133/921 (14%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGA---------PGFPGQKGEQGFEGSKGETGEK 342 G GLPG PG+PG +G +G PGE G GA PG PG+ G+ G G G GE+ Sbjct: 185 GPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGER 244 Query: 343 GE---QGEKGDPALAGL------NGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSL 393 G QG +G P AGL G +GL G G GP GPKGE G G G P G Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR 304 Query: 394 GIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHE 453 G+ G +G PG G G RG G G GPPGP GP G G Sbjct: 305 GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGF------------------- 345 Query: 454 AGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPG 513 G G KGE G G GS GP+G +GEPG P G G G PG G G KG G Sbjct: 346 -PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGA---NG 401 Query: 514 PPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLP 573 PG+ G+PG G +G +G GP GPPG G GE G PG +G G KG+PG +G G P Sbjct: 402 APGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP-VGVQGPP 460 Query: 574 GPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTG 632 GP GE G G GEPG G PG PG RG G RG PG G G GP G G PG G Sbjct: 461 GPAGEEGKRGAR--GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 633 AQGPAGEPGIQGPRGLP---GLPGTPGTPGND------GVPGRDGKPGLPGPPGDPIALP 683 +G GE G G GLP GL G+PG+PG D G G+DG+PG PGPPG Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578 Query: 684 LLGDIGALLKNFCGN----CQASVP------GLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 ++G G K G + VP G GE G G PG +G+ GP Sbjct: 579 VMGFPGP--KGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636 Query: 734 RGPPGIPGREGPKGSKGERGYP---------GIPGEKGDEGLQGIPGIPGAPGPTGPPGL 784 G PG G GP G GE G P G PG G G +G PG G GP GP G Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERN--------------GMSSLYK 830 G G PG GAKG+ G+ G PG G PG G+P ER G Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP-GERGAAGLPGPKGDRGDAGPKGADG 755 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSG 890 G V GP GPPGP G PG GE G G G G G GDRG GPPG AG +G Sbjct: 756 SPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG 815 Query: 891 KPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI----------- 939 PGA G PG GEPG+ G GD G PGP GP+G PG G G PGA+G Sbjct: 816 PPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATG 875 Query: 940 -------MGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMG 992 +G PG G G G G G G +G RG+ G G G +GP GPPG G G Sbjct: 876 FPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKG 935 Query: 993 SPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQA 1052 SPG GP G+PG PG P + Q R F P + Sbjct: 936 SPGADGPAGAPGTPG-PQGIAGQRGVVGLPGQRGERGF-------------PGLPGPSGE 981 Query: 1053 YGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPG-------TSA 1101 G+ GP G G GPPG GP G G GE G G G PG G PG T Sbjct: 982 PGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP 1041 Query: 1102 LGLPGSPGAPGPQGPPGPSGR 1122 G PG+PGAPG GP GP+G+ Sbjct: 1042 AGPPGAPGAPGAPGPVGPAGK 1062 Score = 584 bits (1505), Expect = e-166 Identities = 356/853 (41%), Positives = 407/853 (47%), Gaps = 89/853 (10%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KG +G PGAPGS G G KGEPG G+ G PG G++G++G G G TG G GE+G Sbjct: 430 KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGG 489 Query: 351 PALAGLNGENGLKGDLGPHG------PPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 P G G +G+ G GP G P GPKG G+ G PG LPG+ G+ G G PG Sbjct: 490 PGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP 549 Query: 405 EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGET 464 +G+ G G G G+PGPPGPPG G G+ G KG A G G GE Sbjct: 550 DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGP------KG-----AAGEPGKAGER 598 Query: 465 GLPGFPGSVGPKGQKGEPGE---PFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSP 521 G+PG PG+VGP G+ GE G P G G+RGE G GS G +G PG GPPG G P Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658 Query: 522 GLKGQQGSAGSMGPRGPPGDVGLPGEHGI---PGKQGIKGEKGDPG--GIIGPPGLPGPK 576 G +G G G+ GP G G+ G PGE G+ PG G +G G PG G G G PG Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP 718 Query: 577 GEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG----IGIPGRTG 632 G G PG L G PG G G PGP+G +G+ G G GSPG G +G IG PG G Sbjct: 719 GSQGAPG--LQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAG 776 Query: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692 A G GE G GP G G G PG G G PG G G PG G P A GD GA Sbjct: 777 APGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGA-- 834 Query: 693 KNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGER 752 A PG G G G G + +G GP G G PG G G G Sbjct: 835 -----KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS 889 Query: 753 GYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPP 812 G G PG G G +G G G GP G PG +G G PGP G KG G+DGP G PG P Sbjct: 890 GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTP 949 Query: 813 GPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGE---PGAMGLPGLEG 869 GP GI + G+ L +G P PGP G PG +G G GE PG MG PGL G Sbjct: 950 GPQGIA--GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAG 1007 Query: 870 FPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGING 929 PG G G G G G G PGA G G G G G G G PGP GP+GK G G Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRG 1067 Query: 930 KDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKG 989 + G G G +G G RGP G +G +G G+ G QG+RG G G G GP GPPG+ G Sbjct: 1068 ETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPG 1127 Query: 990 SMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLA 1049 G G GP G G PG Sbjct: 1128 EQGPSGASGPAGPRGPPG------------------------------------------ 1145 Query: 1050 AQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPG 1109 + G PG G +GLPGP G PGP+G G G G P G PG PG PG + G S Sbjct: 1146 --SAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPP--GPPGPPGPPGPPSAGFDFSFL 1201 Query: 1110 APGPQGPPGPSGR 1122 PQ GR Sbjct: 1202 PQPPQEKAHDGGR 1214 Score = 572 bits (1474), Expect = e-163 Identities = 370/925 (40%), Positives = 420/925 (45%), Gaps = 174/925 (18%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHG-------------------APGFPGQKGEQGF 332 G G+PG PG PG G G PG GL G PG G G +G Sbjct: 130 GRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGL 189 Query: 333 EGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGS 392 G G G +G QG G+P GE G G +GP GPPGP G+ GD G G P PG Sbjct: 190 PGPPGAPGPQGFQGPPGEP------GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGE 243 Query: 393 LGIQGPQGP---------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYN 443 G GPQG PG +G RG G G G GP GP G PG G + G Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303 Query: 444 KDNKGNDEHEAG----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 + G G +G+ G TG G PG GP G G PG KGE G +G G Sbjct: 304 RGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 500 IGSQGVKGEPGDPGP------------------------PGLIGSPGLKGQQGSAGSMGP 535 G QGV+GEPG PGP PG+ G+PG G +G +G GP Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 536 RGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGN 595 GPPG G GE G PG +G G KG+PG + G G PGP GE G G GEPG G Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV-GVQGPPGPAGEEGKRGAR--GEPGPTGL 480 Query: 596 PGAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPG---L 651 PG PG RG G RG PG G G GP G G PG G +G GE G G GLPG L Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540 Query: 652 PGTPGTPGNDGV---PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKS 708 G+PG+PG DG PG G+ G PGPPG P A QA V G Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGA----------------RGQAGVMGFP- 583 Query: 709 NKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKG 762 G +G AGEPGK G RG PG PG GP G GE G G PG E+G Sbjct: 584 --GPKGAAGEPGK---------AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG 632 Query: 763 DEGLQGIPGIPGAPGPTGPPGLMGRTGH---------PGPTGAKGEKGSDGPPGKPGPPG 813 ++G G PG G PGP GPPG G+ G PGP+GA+GE+G G G GPPG Sbjct: 633 EQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPG 692 Query: 814 PPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGV 873 P G NG KG P PG G PG +G PG E GA GLPG +G G Sbjct: 693 PAGP--RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPG---ERGAAGLPGPKGDRGD 747 Query: 874 KGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGI 933 G +G G PG G+ G G GPPG G PG++G G G GP G G PG G+ G Sbjct: 748 AGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGP 807 Query: 934 PGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 PG G G PG G G +G+ PGD G++G+ G PG G G GP+G G G+ G+ Sbjct: 808 PGPAGFAGPPGADGQPGAKGE---PGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGA 864 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 G GPPG+ G PG A Sbjct: 865 RGSAGPPGATGFPG--------------------------------------------AA 880 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGP 1113 GR GPPG G GPPG PGP G G KG RGE G G PG +G PG PG G Sbjct: 881 GRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA--GRPG-----EVGPPGPPGPAGE 933 Query: 1114 QGPPGPSGRCNPEDCLYPVSHAHQR 1138 +G PG G P A QR Sbjct: 934 KGSPGADGPAGAPGTPGPQGIAGQR 958 Score = 547 bits (1410), Expect = e-155 Identities = 345/814 (42%), Positives = 393/814 (48%), Gaps = 134/814 (16%) Query: 373 GPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQ 432 G +G KGDTGP GP +GP GPPG++G G+ G GPPG PGPPGPPG Sbjct: 109 GVEGPKGDTGPRGP---------RGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPG----- 154 Query: 433 GIHQTLGGYYNKD-NKGNDEHEAGGLK-----GDKGETGLPGFPGSVGPKGQKGEPGEPF 486 LGG + + G DE GG+ G G GLPG PG+ GP+G +G PGEP Sbjct: 155 -----LGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP- 208 Query: 487 TKGEKGDRGEPGVIGSQGVKGEPGDP---GPPGLIGSPGLKGQQGSAGSMGPRGPPGDVG 543 GEPG G G +G PG P G G G PG G++G G G RG PG G Sbjct: 209 --------GEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAG 260 Query: 544 LPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPR 602 LPG G G G+ G KGD G GP G PG GE G PG+ P G PG G PGAPGP Sbjct: 261 LPGMKGHRGFSGLDGAKGD-AGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319 Query: 603 GPKGERGLPGVHGSPGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTP 655 G +G G G G PG GP G +G G G QGP G G QG RG PG PG Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379 Query: 656 GTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCG-NCQASVPGLKSNKGEEG 714 G G G PG DG+PG G G P G GA + G PG K N GE G Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA--RGPSGPQGPGGPPGPKGNSGEPG 437 Query: 715 GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPG 774 G G + G +G +GPPG G EG +G++GE G G+PG G+ G G G PG Sbjct: 438 APGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG 497 Query: 775 APGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGG 834 A G GP G G G PGP G KG G G PG+ G PG G+ + G Sbjct: 498 ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGS-----------PGS 546 Query: 835 VNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVK---------GDRGPAGPPGI 885 GPPGP G G PGP G PGA G G+ GFPG K G+RG GPPG Sbjct: 547 PGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA 606 Query: 886 AGMSGK------PGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 G +GK G PGP G GE GE+GP G GF G GP+G PG GK PG QG+ Sbjct: 607 VGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK---PGEQGV 663 Query: 940 MGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGP 999 G G GP G RG++G PG+RG QG G G G GA G G G+ G+ G+PG QG Sbjct: 664 PGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGA 723 Query: 1000 PGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPP 1059 PG G+PG ER A L K A G G P Sbjct: 724 PGLQGMPG------------------------ERGAAGLPGPKGDRG--DAGPKGADGSP 757 Query: 1060 GKDGL---------PGPPGDP------------GPQGYRGQKGERGEPG-------IGLP 1091 GKDG+ PGP G P GP G RG G+RGEPG G P Sbjct: 758 GKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPP 817 Query: 1092 GSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G+ G PG A G PG GA G GPPGP+G P Sbjct: 818 GADGQPG--AKGEPGDAGAKGDAGPPGPAGPAGP 849 Score = 462 bits (1189), Expect = e-130 Identities = 294/708 (41%), Positives = 336/708 (47%), Gaps = 92/708 (12%) Query: 451 EHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 + E G++G KG+TG G G GP G+ G PG+P G G G PG Sbjct: 104 DQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQP---------------GLPGPPGPPG 148 Query: 511 DPGPPGLIGS--PGL-----KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDP 563 PGPPGL G+ P L + G GP GP G GLPG G PG QG +G G+P Sbjct: 149 PPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP 208 Query: 564 GGIIGPPGLPGPKGEAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGP 622 G G G GP+G GPPGK+ GE G G PG GP GP+G RGLPG G PG G Sbjct: 209 GEP-GASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGH 267 Query: 623 QGI----GIPGRTGAQGPAGEPGI---------QGPRGLPGLPGTPGTPGNDGVPGRDGK 669 +G G G G GP GEPG GPRGLPG G PG PG G G DG Sbjct: 268 RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG 729 G GPPG A PG G +G AG G S +G Sbjct: 328 TGAAGPPGP-------------------TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQG 368 Query: 730 DIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP------PG 783 G GPPG G GP G+ G G PG G G G+ G PG PGA GP+GP PG Sbjct: 369 VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPG 428 Query: 784 LMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP 843 G +G PG G+KG+ G+ G PG G GPPG P E +G P G Sbjct: 429 PKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG-PAGEEGK-------RGARGEPGPTGL 480 Query: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGP---PGIAGMSGKPGAPGPPGV 900 PGPPG +G PG G PGA G+ G +G G +G GPAGP PG AG G+ G PG G+ Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540 Query: 901 PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGD 960 G PG GP G G PGP G G+PG G G G G+MG PG PKG G+ G G+ Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG---PKGAAGEPGKAGE 597 Query: 961 RGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKK 1020 RG G G G G G G GPPG G G G QGP GSPG G+P A E K Sbjct: 598 RGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657 Query: 1021 YINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK 1080 Q V L P + A G G PG+ G+ GPPG GP+G G Sbjct: 658 PGEQGVP-----------GDLGAPGP---SGARGERGFPGERGVQGPPGPAGPRGANGAP 703 Query: 1081 GERGEPG-IGLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSGRCNPE 1126 G G G G PG+PG G L G+PG GA G GP G G P+ Sbjct: 704 GNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPK 751 Score = 349 bits (896), Expect = 7e-96 Identities = 219/536 (40%), Positives = 247/536 (46%), Gaps = 91/536 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK- 348 N G G GAPG+PG +G G G G GA G PG KG++G G KG G G+ G + Sbjct: 705 NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764 Query: 349 -----GDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G P AG G+ G G GP GP G +G GD G PGPP G G G G PG Sbjct: 765 LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824 Query: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGE 463 +G+ G G G G PGP GP GPPG +G KG A G G G Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPAGPPG------PIGNVGAPGAKG-----ARGSAGPPGA 873 Query: 464 TGLPGFPGSVGPKGQKGE------PGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGL 517 TG PG G VGP G G PG +G KG RGE G G G G PG PGP G Sbjct: 874 TGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGE 933 Query: 518 IGSPGLKGQQGSAGSMGPRGPPGD---VGLPGEHGIPGKQGIKGEKGDPG--------GI 566 GSPG G G+ G+ GP+G G VGLPG+ G G G+ G G+PG G Sbjct: 934 KGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993 Query: 567 IGPPGLPGPKGEAGPPGKS-------LPGEPGLDGNPGAPGPR---GPKGERGLPGVHGS 616 GPPG GP G AGPPG+S G PG DG+PGA G R GP G G PG G+ Sbjct: 994 RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053 Query: 617 PGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK 669 PG +GP G G G G GP G G GP+G G G G G+ G+ G G Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGF 1113 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG 729 GL GPPG P G PG+ G Sbjct: 1114 SGLQGPPGPP-------------------------------------GSPGEQGPSGASG 1136 Query: 730 DIGPRGPP---GIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPP 782 GPRGPP G PG++G G G G PG G GD G G PG PG PGP GPP Sbjct: 1137 PAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192 Score = 283 bits (725), Expect = 5e-76 Identities = 193/484 (39%), Positives = 220/484 (45%), Gaps = 74/484 (15%) Query: 699 CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP 758 C G +S +E E K D+ G GPRGP G PGR+G G G G PG P Sbjct: 92 CPVCPDGSESPTDQETTGVEGPKGDT----GPRGPRGPAGPPGRDGIPGQPGLPGPPGPP 147 Query: 759 GEKGDEGLQG-------------------IPGIPGAPGPTG---PPGLMGRTGHPGPTGA 796 G G GL G +PG G GP G PPG G G GP G Sbjct: 148 GPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGE 207 Query: 797 KGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV 856 GE G+ GP G GPPGPPG +NG G P GPPGP G +G PG Sbjct: 208 PGEPGASGPMGPRGPPGPPG-----KNGDDGE---AGKPGRPGERGPPGPQGARGLPGTA 259 Query: 857 GEPGAMGLPGLEGFPGVKGDRGPAGP---PGIAGMSGKPGAPGPPGVPGE---PGERGP- 909 G PG G G G G KGD GPAGP PG G +G PG GP G+PGE PG GP Sbjct: 260 GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319 Query: 910 --------VGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDR 961 G G PGP GP+G PG G G G G G G GP+G RG+ G PG Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379 Query: 962 GSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKY 1021 G+ G G PG G GA G G PG G+ G PG +GP G G G P + E Sbjct: 380 GAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAP 439 Query: 1022 INQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PGPQGY-- 1076 ++ E V + PA + G G PG GLPGPPG+ PG +G+ Sbjct: 440 GSKGDTGAKGEPGPVGVQGPPGPAGEEGKR--GARGEPGPTGLPGPPGERGGPGSRGFPG 497 Query: 1077 -------RGQKGERGEPG----------IGLPGSPGLPGTSAL-GLPGSPGAPGPQGPPG 1118 +G GERG PG G PG GLPG L G PGSPG G GPPG Sbjct: 498 ADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 1119 PSGR 1122 P+G+ Sbjct: 558 PAGQ 561 Score = 267 bits (682), Expect = 5e-71 Identities = 166/384 (43%), Positives = 181/384 (47%), Gaps = 36/384 (9%) Query: 740 PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE 799 PG E P+G P P Q G+ G G TGP G G G PG G G+ Sbjct: 82 PGAEVPEGEC----CPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQ 137 Query: 800 KGSDGPPGKPGPPGPPGIPFNERNGMSSLY--KIKGGVNVPSYPGPPGPPGPKGDPGPVG 857 G GPPG PGPPGPPG+ N +S Y K GG++VP GP GP GP+G PGP G Sbjct: 138 PGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP---GPMGPSGPRGLPGPPG 194 Query: 858 EPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPG 917 PG G G G PG G GP GP G G GK G G G PG PGERGP G G G Sbjct: 195 APGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARG 254 Query: 918 PEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKG 977 G +G PG+ G G G G G G GPKGE G G G G G RG PG G G Sbjct: 255 LPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPG 314 Query: 978 AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVF 1037 A GP G GN G+ G+ G GP G G PG P AV K + R E V Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPG-AVG---AKGEAGPQGPRGSEGPQGV- 369 Query: 1038 LSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSPGLP 1097 G PGPPG G GP G+PG G G KG G PGI G+PG P Sbjct: 370 ---------------RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA--GAPGFP 412 Query: 1098 GTSALGLPGSPGAPGPQGPPGPSG 1121 G G G GP GPPGP G Sbjct: 413 GAR-----GPSGPQGPGGPPGPKG 431 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 599 bits (1545), Expect = e-171 Identities = 400/965 (41%), Positives = 461/965 (47%), Gaps = 165/965 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGE-KGEQGEKGD 350 G G+PG G+ G KG G PG GL G PGFPG +G+ G +G KGET + +G+ G GD Sbjct: 496 GVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 351 PALAGLNGENGLKG---DLGPHGPPGPKGE------KGDTGPPGPPALPGSLGIQGPQGP 401 P L G G GL G G G PGPKGE KGD GPPG P PGS G GP GP Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP 615 Query: 402 PGK--------EGQRGRRGKTGPPGK-------------PGPPGPPGPPGIQGIHQTLGG 440 PG +G +G G GPPG+ PGPPGPPGPPG G Q G Sbjct: 616 PGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPG-PQGPPG 674 Query: 441 YYNKDNKGNDEHEAGGLKGDKGETGLPG--FPGSVGPKGQKGEPGEPFTKGEKGDRGEPG 498 K D GL G GE G+PG FPG GPKG +G PG + G G GEPG Sbjct: 675 IPGSLGKCGDP----GLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730 Query: 499 VIGSQGVKGEPGDPGP--PGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGI 556 + G G+ G G+P PG G+PG G++G++G G G PG LPG G PG +G+ Sbjct: 731 LPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG---LPGLPGTPGNEGL 787 Query: 557 KGEKGDPGGIIGPPGLPGPKGEAGPPGK---------SLPGEPGLDGNPGAPGPRGPKGE 607 G +GDPG PGP GE GPPG+ LPG GL G G G GPKG+ Sbjct: 788 DGPRGDPGQ-------PGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGD 840 Query: 608 RGLPGVH--GSPGDIGPQGI-------------GIPGRTGAQGPAGEPGIQGPRGLPGLP 652 G+PG+ G PG+ G GI G PG G GP GE G+ G G PG Sbjct: 841 PGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI 900 Query: 653 GTPGTPGNDGVPGRDGKPGLPGP------------------PGDPIALPLLGDIGAL-LK 693 G PG PGN G PG+ G PG+PG PG ++GD G LK Sbjct: 901 GPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLK 960 Query: 694 NFCGNCQAS-------VPGLKSNKGEEGGAGEPGK---YDSMARKGDIGPRGPPGIPGRE 743 F GN +PGLK KG G AG PG S G+ G RG PG G Sbjct: 961 GFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNM 1020 Query: 744 GPKGSKGERGYPGIPGEKGDEGLQGIPGI--------------PGAPGPTGPPGL----- 784 G GSKG+RG G PG G GL GI G+ PG PGPTG PGL Sbjct: 1021 GMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMG 1080 Query: 785 -MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP 843 G G PGP G G G +G PG PG PG PG P +G IKG + P GP Sbjct: 1081 KKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKP--GPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 844 PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG----PAGPPGIAGMSGKPGAPGPPG 899 PG PG G PGP+G G G G+ G G KG+ G P GP G G G G G PG Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG 1198 Query: 900 VPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG 959 PG PG +G +GD G P GP+G G G G+PGA I G+ G+RGP G RG G PG Sbjct: 1199 FPGLPGRKGAMGDAG---PRGPTGIEGFPGPPGLPGAI-IPGQTGNRGPPGSRGSPGAPG 1254 Query: 960 DRGSQGER--GKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADA--VSF 1015 G G G G G G GP GPPG G MG PG G PG+PG+PG D F Sbjct: 1255 PPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGF 1314 Query: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP------PG 1069 +K E+ FL + P + G GPPG G PG PG Sbjct: 1315 PGVKG----------EKGNPGFLGSIGPPGPI------GPKGPPGVRGDPGTLKIISLPG 1358 Query: 1070 DPGPQGYRGQKGERGEPGIGLPGSPGLPGTSAL----GLPGSPGAPGPQGPPGPSGRCNP 1125 PGP G G+ G +GEPG PG PG G G G PG PGP G G G Sbjct: 1359 SPGPPGTPGEPGMQGEPGP--PGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGE 1416 Query: 1126 EDCLY 1130 + L+ Sbjct: 1417 PESLF 1421 Score = 588 bits (1517), Expect = e-168 Identities = 396/962 (41%), Positives = 459/962 (47%), Gaps = 166/962 (17%) Query: 289 PNKGEAGLPGAPGSPGQKGHKGEPGENGLH--GAPGFPGQKGEQGFEGSKGETGEKGE-Q 345 P GL GAPG PG KG KGE G G G PG PG G G GS G G G+ Sbjct: 383 PGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIV 442 Query: 346 GEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP--------PGPPALPGSLGIQG 397 KG P G++GL G LG G PG G KG+ G PGPP LPG G+ G Sbjct: 443 FRKGPP------GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496 Query: 398 PQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 +G PG++G G +G G PG G PG PG PG QG G K E + G Sbjct: 497 VKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKG---EKGETLQPEGQVGVP 553 Query: 456 ---GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP 512 GL+G G GL G PG+ G KG G GE GEKGD+G PG GS G G G Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613 Query: 513 GPPGL--IGSPGLKGQQGSAGSMGPRGPPGDVG-------LPGEHGIPGKQGIKGEKGDP 563 GPPG G PGL+G QG G+ GP G G G +PG G PG G G +G P Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPP 673 Query: 564 G-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP------KGERGLPG 612 G G G PGLPGP GE G PG PG PG G+ G PG +G GE GLPG Sbjct: 674 GIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPG 733 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG---LPGLPGTPGTPGNDGVPGRDGK 669 G PG G + +PG G G GE G G G LPGLPG PGTPGN+G+ G G Sbjct: 734 KPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGD 793 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK-----YDS 724 PG PGPPG+ G G ++ G +PGL KG++G G+ G Sbjct: 794 PGQPGPPGEQ------GPPGRCIEGPRG--AQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGP 778 + R G G G PGIPG +G G G+RGYPG PG E G G+ G PG G PGP Sbjct: 846 LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGP 905 Query: 779 TGPPGLMGRTGHPGPTGAKGE------KGSDGPPGKPGPP---------GPPGI------ 817 G PG G+ G PG G KG+ KG G G PGP G PG+ Sbjct: 906 PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGN 965 Query: 818 PFNERN----GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG---- 869 P + N GM L +KG PGP GPPGP+GD G G PG GL G+ G Sbjct: 966 PGEKGNRGVPGMPGLKGLKG------LPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGN 1019 Query: 870 --FPGVKGDRGPAGPPGIAGMSG--------------------KPGAPGPPGVPGEPGER 907 PG KG RG G PG AG G +PG PGP G PG PG+ Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDM 1079 Query: 908 GPVGDIGFPGPEG------PSGKPGINGKDGIPGA------------QGIMGKPGDRGPK 949 G G++G PGP G P G PG G G+PG +G++G PG RGP Sbjct: 1080 GKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPP 1139 Query: 950 GERGDQGIPGD---RGSQGERGKPGLTGMKGAIG----PMGPPGNKGSMGSPGHQGPPGS 1002 G G G PG RG QG G PG G KG G P GP GN G+ G+ G +G PG Sbjct: 1140 GLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGF 1199 Query: 1003 PGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKD 1062 PG+PG +K + + F LP A++ Q G GPPG Sbjct: 1200 PGLPG-----------RKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQT-GNRGPPGSR 1247 Query: 1063 GLPGPPGDPGPQGYR--GQKGERGEPGIGLPGSPGLPGTSA-LGLPGSPGAPGPQGPPGP 1119 G PG PG PGP G G KG++G +G PG G PGT+ +G PG GAPG G PGP Sbjct: 1248 GSPGAPGPPGPPGSHVIGIKGDKGS--MGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGP 1305 Query: 1120 SG 1121 G Sbjct: 1306 RG 1307 Score = 585 bits (1508), Expect = e-167 Identities = 395/964 (40%), Positives = 465/964 (48%), Gaps = 192/964 (19%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG------EKGE 344 +G +GLPG GSPG G G G GL G PG G KGEQGF G G G G Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 345 QGEKGDPALA-----GLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQ 399 +G+KG PA G+ GL G GP G PGP G G GPPGPP G G GP+ Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 400 GPPGKEGQR--GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG-- 455 GP G G+R G +G+ G G GPPGPPG + TL G N+ + ++ + G Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGT-----VIVTLTGPDNRTDLKGEKGDKGAM 267 Query: 456 ---------GLKGDK--GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 GL G+ E G PG PG G G+ G PG P ++G KG+RG PG++G G Sbjct: 268 GEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDG 327 Query: 505 VKGEPGDPGPPGLIG---------------SPGLKGQQGSAGSMGPRGPPGDVGLPGEH- 548 +KG+ GD GPPG G +PG G +G+ G GP GPPG G PG Sbjct: 328 IKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSR 387 Query: 549 -------GIPGKQGIKGEKGDPG----------GIIGPPGLPGPKGEAGPPG-----KSL 586 G PG +G KGE+G PG G G PGLPG G GPPG K Sbjct: 388 PGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP 447 Query: 587 PGE---PGLDGNPGAPGPRGPKGERGL--------PGVHGSPGDIGPQGI-GIPGRTGAQ 634 PG+ PG G+PG PG GPKGE GL PG G PG G G+ GIPGR GA Sbjct: 448 PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKP----GLPGPPGDPIALPLLGDIGA 690 G G PG G GLPG PG PG G+ G+ G G+ G G PGDP L G G Sbjct: 508 GLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDP---GLRGQPG- 563 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 + + G+ G +G G G+ KGD GP G PG PG GP G G Sbjct: 564 ---------RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPG-LMGRTGHPGPTGAKGEKGSDGPPGKP 809 GY G GE G +G QG+PG PG PG GP G L T PGP G G PPG P Sbjct: 615 PPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPG------PPGHP 667 Query: 810 GPPGPPGIPFN-ERNGMSSLYKIKGGVNVPS--YPGPPGPPGPKGDPGPVGE---PGAMG 863 GP GPPGIP + + G L G +P +PGPPGP G +G PG G PG MG Sbjct: 668 GPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMG 727 Query: 864 LPGLEGFPGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGE 906 PGL G PG+ G +G P GP PG G SG+ PG PG PG PG G Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGL 787 Query: 907 RGPVGDIGFPGPEGPSGKPGI-----NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-D 960 GP GD G PGP G G PG G G+PG G+ G+ G RG G +GD GIPG D Sbjct: 788 DGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLD 847 Query: 961 R-GSQGERGKPGLTGMKGAIGPMGP---PGNKGSMGSPGHQG------------PPGSPG 1004 R G GE G PG+ G +G +GP+G PGN G +G PG G PPG PG Sbjct: 848 RSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPG 907 Query: 1005 IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 PG P +R + + +K G+ G PG G Sbjct: 908 NPGTPG---------------------QRGSPGIPGVK-----------GQRGTPGAKGE 935 Query: 1065 PGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSP------GAPGPQGPP 1117 G G+PGP G++GEPG+ G G+PG G G+PG P G PGP GPP Sbjct: 936 QGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR--GVPGMPGLKGLKGLPGPAGPP 993 Query: 1118 GPSG 1121 GP G Sbjct: 994 GPRG 997 Score = 583 bits (1504), Expect = e-166 Identities = 413/1010 (40%), Positives = 469/1010 (46%), Gaps = 212/1010 (20%) Query: 282 KDQCQCIP---NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGE 338 K QC C KGE G PG PGSPGQKG G G G G GFPG G GSKG Sbjct: 36 KGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGL---PGLTGSKGV 92 Query: 339 TGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGP---PALPGSLGI 395 G G G G P L G G G G +G G G KGE+G G PG P +PG+ G+ Sbjct: 93 RGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGL 152 Query: 396 QGPQGPPGKE--------------GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGY 441 +G +G P KE G G +G GPPG PGP GPPGPPG G +G Sbjct: 153 KGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR 212 Query: 442 YNKDNKGNDEHEAGGLKGDKGETGLPGFPGSV-----------------GPKGQKGEPGE 484 K + G G +G KG TG PG PG+V G KG GEPG Sbjct: 213 GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGP 272 Query: 485 PFTKG--------EKGDRGEPGVIGSQGVKGEPGDPGP---------PGLIGSPGLKGQQ 527 P G EKG G+PG+ G G G PG PG PGL+G G+KGQ+ Sbjct: 273 PGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQK 332 Query: 528 GSAGSMGPRGP---------PGDVGLPGEHGIPGKQGIKGEKGDPG-------------G 565 G G G RGP GD G PG G G +G +G G PG G Sbjct: 333 GDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRG 392 Query: 566 IIGPPGLPGPKGEAGPPGK---SLPGEPGLDGN---PGAPGPRGPKGE----RGLPGVHG 615 G PGL G KGE G PGK PG PG G+ PG+PGP GP G+ +G PG HG Sbjct: 393 APGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHG 452 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPGI---QGP--RGLPGLPGTPGTPGNDGVPGRDGKP 670 PG +G PG G GP GEPG+ Q P G PGLPG PG G G+PGR G Sbjct: 453 LPGYLGS-----PGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAA 507 Query: 671 GLPGPPGDPIALPLLGDIGALLKNFCGNCQA-SVPGLKSNKGE----EGGAGEPGKYDSM 725 GL G PG P G+ G L F G A PGLK KGE EG G PG Sbjct: 508 GLKGSPGSP------GNTG--LPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPG---DP 556 Query: 726 ARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP---- 781 +G G +G GIPG G KG G +G + GEKGD+G G PG PG+PGP GP Sbjct: 557 GLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPP 616 Query: 782 -------PGLMGRTGHPGPTGAKGEKGSDGP-------PGKPGPPGPPGIPFNERNGMSS 827 PGL G G PG G GE G G PG PGPPGPPG P + G Sbjct: 617 GYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQ--GPPG 674 Query: 828 LYKIKGGVNVPSYPGP-----------PGPPGPKGD------PGPVGEPGAMGLPGLEGF 870 + G P PGP PGPPGPKGD G +G PG MG PGL G Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGK 734 Query: 871 PGVKGDRG------PAGP-----PGIAGMSGK------PGAPGPPGVPGEPGERGPVGDI 913 PG+ G +G P GP PG G SG+ PG PG PG PG G GP GD Sbjct: 735 PGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDP 794 Query: 914 GFPGPEGPSGKP-----GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPG-DR-GSQGE 966 G PGP G G P G G G+PG G+ G+ G RG G +GD GIPG DR G GE Sbjct: 795 GQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGE 854 Query: 967 RGKPGLTGMKGAIGP------------MGPPGNK---GSMGSPGHQGPPGSPGIPGIPAD 1011 G PG+ G +G +GP +GPPG G MG PG GPPG PG PG P Sbjct: 855 TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914 Query: 1012 AVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDP 1071 S + Q P A G PGP + G G+P Sbjct: 915 RGS-----------------PGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEP 957 Query: 1072 GPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G +G+ G GE+G G+ PG PGL G GLPG G PGP+G G +G Sbjct: 958 GLKGFAGNPGEKGNRGV--PGMPGLKGLK--GLPGPAGPPGPRGDLGSTG 1003 Score = 566 bits (1459), Expect = e-161 Identities = 397/1039 (38%), Positives = 471/1039 (45%), Gaps = 244/1039 (23%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGEN--GLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEK 348 KGE G GA G PG G G PGE+ GAPG PG +G+ G +G G G +G +G + Sbjct: 258 KGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNR 317 Query: 349 GDPALAGLNGENGLKGDLGPHGPPGPKG------EKGDTGPPGPPALPGSLGIQGPQGPP 402 G P L G +G G KGD+GP G GP EKGD G PGPP G+ G QGP GPP Sbjct: 318 GFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPP 377 Query: 403 GKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKG 462 G G G +PG G PG PG++G +K +G +A G G G Sbjct: 378 GVPGSPGS-------SRPGLRGAPGWPGLKG---------SKGERGRPGKDAMGTPGSPG 421 Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV------KGEPG------ 510 G PG PGS GP G G+ F KG GD G PG +GS G+ KGEPG Sbjct: 422 CAGSPGLPGSPGPPGPPGDI--VFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQC 479 Query: 511 --DPGPPGLIGSPGLKG------QQGSAGSMGPRGPPGDVGLPGEHGIPGKQG---IKGE 559 PGPPGL G PGL G +QG+AG G G PG+ GLPG G PG QG +KGE Sbjct: 480 PYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGE 539 Query: 560 KGD---PGGIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGP---RGPKGERGLPG 612 KG+ P G +G PG PG +G+ G G +PG PG+ G PG G G KG++G PG Sbjct: 540 KGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPG 599 Query: 613 VHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG-------------TPG 659 GSPG GP G P GP GEPG+QG +G+PG PG PG PG Sbjct: 600 DPGSPGSPGPAG---PAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEP 719 G PG G PG GPPG P +L GD G L G G G +G G P Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPG--LPGPDGEPGIPGIGFPGPPGPKGDQGFP 714 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSK-----GERGYPGIPGEKGDEG------LQG 768 G S+ G +G G PG PG G KG G G PG PGE+G+ G L G Sbjct: 715 GTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPG 774 Query: 769 IPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE--------------------KGSDGPPGK 808 +PG+PG PG G G G G PGP G +G KG G GK Sbjct: 775 LPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGK 834 Query: 809 PGPPGPPGIPFNERNGMSSLYKIKGGVNVPS------------YPGPPGPPGPKGD---- 852 GP G PGIP +R+G G +P YPG PG GP G+ Sbjct: 835 TGPKGDPGIPGLDRSGFPGE---TGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891 Query: 853 -----------PGPVGEPGAMGLPGLEGFPGVKGDR------------------------ 877 PGP G PG G G G PGVKG R Sbjct: 892 GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951 Query: 878 GPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGP------SGKPGINGKD 931 G G PG+ G +G PG G GVPG PG +G G G GP GP +G PG G Sbjct: 952 GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011 Query: 932 GIPGAQGIMGKPGDRGPK------GERGDQGIPGDRGSQGERGKPGLT------------ 973 GIPG+ G MG PG +G + G G G+PG G QG++G+PG + Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071 Query: 974 --------GMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPA--DAVSFEEIKKYIN 1023 G KG +G GPPG+ G G G G PGSPG+PG P + F+ IK + Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131 Query: 1024 QEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD----------PGP 1073 +R LP + G G G+DG+PGP G+ PGP Sbjct: 1132 PPGIR----------GPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 1074 Q---GYRGQKGERGEPGI----------------------GLPGSPGLPG------TSAL 1102 + G +G KG+RG PG G PG PGLPG T Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNR 1241 Query: 1103 GLPGSPGAPGPQGPPGPSG 1121 G PGS G+PG GPPGP G Sbjct: 1242 GPPGSRGSPGAPGPPGPPG 1260 Score = 477 bits (1228), Expect = e-134 Identities = 324/824 (39%), Positives = 373/824 (45%), Gaps = 166/824 (20%) Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPG 468 G +G+ G G PGPPG PG KG TG G Sbjct: 43 GAKGEKGEKGFPGPPGSPG--------------------------------QKGFTGPEG 70 Query: 469 FPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQG 528 PG GPKG G PG +KG +G G PG GS G+ G PG+ GP GL+G PG G +G Sbjct: 71 LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE--------KGDPG--GIIGPPGLPGPKGE 578 G G G G G+PG G+ G++G + KGDPG G GP GLPGP G Sbjct: 131 EQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGF 190 Query: 579 AGPPGKSLPGEPGLDGNPGAPGPRGPKG-----------ERGLPGVHGSPGD-------- 619 GP G PG PG G PGA GPRGPKG ERG+ G+ G PG Sbjct: 191 PGPVGP--PGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 620 IGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGLP-----GTPGTPGNDGVPGRDGKPGLP 673 GP + G G +G GEPG GP GLPG G PG PG G PG+DG PG P Sbjct: 249 TGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFP 308 Query: 674 GPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGP 733 G G G +G + + G K + G G G YD+ KGD G Sbjct: 309 GSEGVKGNRGFPGLMG----------EDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGT 358 Query: 734 RGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGP 793 GPPG G GP+G G G PG PG GL+G PG PG G G G G+ G Sbjct: 359 PGPPGPRGARGPQGPSGPPGVPGSPGSSRP-GLRGAPGWPGLKGSKGERGRPGKDAM-GT 416 Query: 794 TGAKGEKGSDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG- 851 G+ G GS G PG PGPPGPPG I F R G + + G + P PG GP G G Sbjct: 417 PGSPGCAGSPGLPGSPGPPGPPGDIVF--RKGPPGDHGLPGYLGSPGIPGVDGPKGEPGL 474 Query: 852 -------DPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEP 904 PGP G PG GL G++G PG +G G G PG G +G PG PG PG G+P Sbjct: 475 LCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDP 534 Query: 905 GERG-------PVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP---KGERGD 954 G +G P G +G PG G G+PG G DGIPG G+ G PG +G GE+GD Sbjct: 535 GLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGD 594 Query: 955 QGIPGDRGSQGE--------------RGKPGLTGMKGAIGPMGPPGNKGSMGS------- 993 QG PGD GS G +G+PGL G +G G GPPG G G Sbjct: 595 QGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPV 654 Query: 994 ---------PGHQGPPGSPGIPG------------------IPADAVSFEEIKKYINQEV 1026 PGH GP G PGIPG IP K Sbjct: 655 PGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKG----- 709 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDG-----LPGPPGDPGPQGYRGQKG 1081 ++ L P M G+PG PG G +PG PG PG G RG G Sbjct: 710 ----DQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSG 765 Query: 1082 ERGEPGI-GLPGSPGLPGTSALGLP-GSPGAPGPQGPPGPSGRC 1123 E GE G+ GLPG PG PG L P G PG PGP G GP GRC Sbjct: 766 EHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRC 809 Score = 342 bits (877), Expect = 1e-93 Identities = 245/649 (37%), Positives = 281/649 (43%), Gaps = 173/649 (26%) Query: 600 GPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPG 659 G +G KGE+G PG GSPG + G GP G PG QGP+G PGLPG G+ G Sbjct: 43 GAKGEKGEKGFPGPPGSPG-----------QKGFTGPEGLPGPQGPKGFPGLPGLTGSKG 91 Query: 660 NDGV---PGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA 716 G+ PG G PGLPG PG+ L+G VPG +KGE+G Sbjct: 92 VRGISGLPGFSGSPGLPGTPGNTGPYGLVG----------------VPGCSGSKGEQGFP 135 Query: 717 GEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGE-----------RGYPGIPGEKGDEG 765 G PG G PGIPG G KG KG +G PG+PG G +G Sbjct: 136 GLPGTL------------GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQG 183 Query: 766 LQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE--------KGSDGPPGKPGPPGPPGI 817 L G PG PG GP GPPG G G GP G KG KG G G GPPGPPG Sbjct: 184 LPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGT 243 Query: 818 PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKG--------------DPGPVGEPGAMG 863 G + +KG G PGPPGP G DPG G+PG G Sbjct: 244 VIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDG 303 Query: 864 LPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGV------------PGEPGERGPVG 911 +PG G GVKG+RG G G G+ G+ G GPPG G+ G GP G Sbjct: 304 VPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPG 363 Query: 912 DIGFPGPEGPSGKPGINGKDGI--PGAQGIMGKPGDRGPKGERGDQG--IPGDRGSQGER 967 G GP+GPSG PG+ G G PG +G G PG +G KGERG G G GS G Sbjct: 364 PRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCA 423 Query: 968 GKPGLTGMKGAIGP-------MGPPGNKG------SMGSPGHQGP--------------P 1000 G PGL G G GP GPPG+ G S G PG GP P Sbjct: 424 GSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIP 483 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK-LPAAMLAAQAYGRPGPP 1059 G PG+PG+P L +K +P AA G PG P Sbjct: 484 GPPGLPGLPG---------------------------LHGVKGIPGRQGAAGLKGSPGSP 516 Query: 1060 GKDGLPGPPGDPGPQGYRGQKGERGEP-----GIGLPGSPGL---PGTSAL-GLPGSPGA 1110 G GLPG PG PG QG G KGE+GE +G+PG PGL PG L G+PG+PG Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576 Query: 1111 PG------------------PQGPPGPSGRCNPEDCLYPVSHAHQRTGG 1141 G P G PG G P P + Q G Sbjct: 577 KGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPG 625 Score = 186 bits (471), Expect = 1e-46 Identities = 111/286 (38%), Positives = 135/286 (47%), Gaps = 51/286 (17%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGF----EGSKGETGEKGEQG 346 +G GLPG PGSPG G +G+ G +G+ PG G+KGE G G +G G +G +G Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGI---PGPAGEKGETGLLRAPPGPRGNPGAQGAKG 1192 Query: 347 EKGDPALAGLNGENGLKGDLGPHGPPG-----------------------PKGEKGDTGP 383 ++G P GL G G GD GP GP G P G +G G Sbjct: 1193 DRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGA 1252 Query: 384 PGPPALPGS-----------LGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQ 432 PGPP PGS +G GP+GPPG G G G+ G PG PG PGP G PG Q Sbjct: 1253 PGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312 Query: 433 GIHQTLGGYYNKDNKGN-------DEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEP 485 G G N G+ G++GD G + PGS GP G GEPG Sbjct: 1313 GFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG-- 1370 Query: 486 FTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAG 531 +GE G G PG +G G +G+PG G PG G G KG +GS G Sbjct: 1371 -MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415 Score = 152 bits (384), Expect = 2e-36 Identities = 102/275 (37%), Positives = 121/275 (44%), Gaps = 61/275 (22%) Query: 876 DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKP---------G 926 D+G G G G+ G PGPPG PG+ G GP G PGP+GP G P G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPE---GLPGPQGPKGFPGLPGLTGSKG 91 Query: 927 INGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 + G G+PG G G PG G G G G+PG GS+GE+G PGL G G G G G Sbjct: 92 VRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAG 151 Query: 987 NKGSMGSPGHQ-----GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 KG G+P + G PG+PG P Sbjct: 152 LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQ----------------------------- 182 Query: 1042 KLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQK--GERGEPGI-GLPGSPGLPG 1098 LP G PGPPG G PG G GP+G+ G++ G +GE G+ GL G PG PG Sbjct: 183 GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPG 242 Query: 1099 TSAL------------GLPGSPGAPGPQGPPGPSG 1121 T + G G GA G GPPGPSG Sbjct: 243 TVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSG 277 Score = 141 bits (355), Expect = 4e-33 Identities = 90/231 (38%), Positives = 110/231 (47%), Gaps = 35/231 (15%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGF-----EGSKGETGEKGEQ 345 KG+ G PG PG PG+KG G+ G G G GFPG G G G++G G +G Sbjct: 1191 KGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250 Query: 346 GEKGDPALAGLN--GENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G G P G + G G KG +G GP GP G GD GPPG PG+ G+ GP+G PG Sbjct: 1251 GAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPG 1310 Query: 404 KEGQRGRRGKTGPPG------KPGPPGPPGPPGIQGIHQTLG--------GYYNKDNKGN 449 +G G +G+ G PG PGP GP GPPG++G TL G + Sbjct: 1311 FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPG 1370 Query: 450 DEHEAG-----------GLKGDKGETGLPGFPGSVGPKG---QKGEPGEPF 486 + E G G +G G+ G PG PG G KG KGEP F Sbjct: 1371 MQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPESLF 1421 Score = 133 bits (335), Expect = 8e-31 Identities = 73/168 (43%), Positives = 83/168 (49%), Gaps = 24/168 (14%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KG G PG G PG G G PG G G PG PG +G+ GF+G G GEKG G Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPG--- 1325 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGD------TGPPGPPALPGSLGIQGPQGPPG 403 G G G +GP GPPG +G+ G G PGPP PG G+QG GPPG Sbjct: 1326 ------FLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPG 1379 Query: 404 KEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDE 451 G G G G PGK G PG PGP G +G NK +KG E Sbjct: 1380 PPGNLGPCGPRGKPGKDGKPGTPGPAGEKG---------NKGSKGEPE 1418 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 596 bits (1537), Expect = e-170 Identities = 377/914 (41%), Positives = 437/914 (47%), Gaps = 127/914 (13%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 +KGEAG G G+ G G +G PGE G G G PGQ+G G G G G G G G Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG 378 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQ---GPQGPPGKEG 406 P G+ GE G G GP GP G +GE G GP G P LPG++G G +GP G G Sbjct: 379 FPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPG 438 Query: 407 QRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG-----GLKG 459 G G GPPG PGP G GP GI+G G G+ + + G G G Sbjct: 439 TSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG 498 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTK---------GEKGDRGEPGVIGSQGVKGEPG 510 ++G+ G G PG+VGP G GE G P + G KG +GE G +GS G KG G Sbjct: 499 EEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQG 558 Query: 511 DPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPP 570 DPG PG G PG +G G+ G GP G G +G PGE G PG G G +G PG + Sbjct: 559 DPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSM---- 614 Query: 571 GLPGPKGEAGPPGK-------SLPGE------------------PGLDGNPGAPGPRGPK 605 GLPGPKG +G PGK +PG+ PGL G G GP GP Sbjct: 615 GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPT 674 Query: 606 GERGLPGVHGSPGD---IGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGND 661 G +GLPG G PG+ G QG+ G PG G GP GE G G RG PG+ G PG G Sbjct: 675 GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMA 734 Query: 662 GVPGRDGKPGLPGPPGDPIALPLLGDIGAL-LKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 G G DG G PGP G P GD G L+ G + + G KG+ GG GE G Sbjct: 735 GGHGPDGPKGSPGPSGTP------GDTGPPGLQGMPG--ERGIAGTPGPKGDRGGIGEKG 786 Query: 721 KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGI---------PGEKGDEGLQGIPG 771 + G G GP G PG GP G KGE G G+ PG +G+ G G G Sbjct: 787 AEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVG 846 Query: 772 IPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKI 831 G GP G PG+ G G PG G G G G G PGP GP G+P G+ Sbjct: 847 FAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP-----GLKGGRGT 901 Query: 832 KGGVNVPSYP------GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVK---GDRGPAGP 882 +G +P GPPGP G G GP+GEPG G PGL G PG GDRGPAGP Sbjct: 902 QGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGP 961 Query: 883 PGIAGMSGKP---GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 PG G G P G PGP G PG G G G +G PG G G PG+ G G PG G Sbjct: 962 PGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGP 1021 Query: 940 MGKPGDRGPK---GERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH 996 G GD+GP G G G G+ G +G G G G GA+G G G+ G G PG Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGS 1081 Query: 997 QGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRP 1056 QG PG+PG G P DA Q P + G P Sbjct: 1082 QGAPGTPGPVGAPGDA--------------------------GQRGDPG---SRGPIGPP 1112 Query: 1057 GPPGKDGLPGP------PGDPGPQGYRGQKGERGEPGI-GLPGSPGLPG-TSALGLPGSP 1108 G GK GLPGP GD G +G RGQKG RG G+ GLPG PG G + G+PG Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF 1172 Query: 1109 GAPGPQGPPGPSGR 1122 G GP GP GPSG+ Sbjct: 1173 GPRGPPGPVGPSGK 1186 Score = 595 bits (1535), Expect = e-170 Identities = 376/912 (41%), Positives = 432/912 (47%), Gaps = 151/912 (16%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KGEAG GA G G +G +GE G G G+PG PG G G G+KG TG G G G Sbjct: 386 KGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS 445 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 G G G G G G PG G G G GP PG GIQGP GPPG+EG+RG Sbjct: 446 AGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGP 505 Query: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470 RG G G PGP G G PG +G G+D GL G KG G G Sbjct: 506 RGDPGTVGPPGPVGERGAPGNRGF------------PGSD-----GLPGPKGAQGERGPV 548 Query: 471 GSVGPKGQKGEPG---EPFTKGEKGDRGEPGVIGSQGVKGE---PGDPGPPGLIGSPGLK 524 GS GPKG +G+PG EP G +G G PGV G +G G PG+ G PG GS G++ Sbjct: 549 GSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIR 608 Query: 525 GQQGSAGSMGPRGPPGDVGLPGEHG---IPGKQGIKGEKGD--PGGIIGPPGLPGPKGEA 579 GQ GS G GP+G GD G PGE G +PG++G G+ G+ P G +GPPGL G +GE Sbjct: 609 GQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ 668 Query: 580 GPPG----KSLPGEPG------------LDGNPGAPGPRGPKGERGLPGVHGSPGDIG-- 621 GPPG + LPG PG + G+PGA GP GP+GERG PG G PG G Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLP 728 Query: 622 -----PQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPG------TPGTPGN---------D 661 G G G G+ GP+G PG GP GL G+PG TPG G+ + Sbjct: 729 GEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE 788 Query: 662 GVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK 721 G G DG GLPGP G P A G K G G G PG Sbjct: 789 GTAGNDGARGLPGPLGPP-------------------GPAGPTGEKGEPGPRGLVGPPGS 829 Query: 722 YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGP 781 + +G+ GP G G G +GP G G +G PG PG+KGD G G G+ G+PGP GP Sbjct: 830 RGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGP 889 Query: 782 ---------------------PGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFN 820 PG GR G PGP GA G G G PGK GPPG G P Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP-- 947 Query: 821 ERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPA 880 G +G P PG G PG G PGP G PG G G G G+ G RG Sbjct: 948 ---GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004 Query: 881 GPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIM 940 G PG+ G +G PG GP G G+ G GPVG G GP G G G G DG PG G + Sbjct: 1005 GMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAV 1064 Query: 941 GKPGDRG---PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ 997 G+ GDRG P G G QG PG G G G G G G+ GP+GPPG G G PG Q Sbjct: 1065 GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQ 1124 Query: 998 GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPG 1057 GP G G G D Q+ R F G PG Sbjct: 1125 GPRGDKGDHGDRGDR----------GQKGHRGF-------------------TGLQGLPG 1155 Query: 1058 PPGKDG------LPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGT-SALGLPGSPG 1109 PPG +G +PGP G GP G G G+ G PG +G G PG+ G+ G G PG Sbjct: 1156 PPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPG 1215 Query: 1110 APGPQGPPGPSG 1121 PGP GPPGP G Sbjct: 1216 EPGPPGPPGPPG 1227 Score = 594 bits (1531), Expect = e-169 Identities = 378/959 (39%), Positives = 458/959 (47%), Gaps = 165/959 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG--EKG 349 G AG PG+ G G++G KG PG G G G PG G+ G G G G G Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191 Query: 350 DPALAGLNGENGLK----------GDLGPHGPPGPKGEKGDTGPPGPPALPGS------L 393 +AGL+ ++GL G +GP GP G +G++G GP GPP PG + Sbjct: 192 SAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPI 251 Query: 394 GIQGPQGPPGKEGQRGRRGKTGPPGK------PGPPGPPGPPGIQGIHQTLGGYYNKDNK 447 G +GP+GPPGK G+ G G+ G PG+ PG G PG PG+ G+ G + K Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311 Query: 448 GNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKG 507 G E A G KG+ G TG G G +GP+G GE G +G G RG G+ G G G Sbjct: 312 G--EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG 369 Query: 508 EPGDPGPPGLIGSPGLKGQQGSAGSMGPRGP---------PGDVG---LPGEHGIPGKQG 555 G PG G G+PG+KG+ G G+ GP GP PG VG LPG G G G Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429 Query: 556 IKGEKGDPG-----GIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERG 609 KG G PG G GPPG PGP+G GP G + PG+PG+ G G GP+G G G Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHG 489 Query: 610 LPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPG--------- 659 + G G PG+ G +G G PG G GP GE G G RG PG G PG G Sbjct: 490 IQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVG 549 Query: 660 NDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEP 719 + G G G PG PG PG P A L G+ PG++ +G+ G G P Sbjct: 550 SSGPKGSQGDPGRPGEPGLPGARGLTGN----------------PGVQGPEGKLGPLGAP 593 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPT 779 G+ G IG RG PG G GPKGS G+ G PG G G G +G PG G GP+ Sbjct: 594 GEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653 Query: 780 GP---PGLMGRTGH---PGPTGAKGEKGSDGPPGKPGPPGPPGIPFN------------- 820 GP PGL G G PGPTG +G G GPPG+ G PG G+P + Sbjct: 654 GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713 Query: 821 ----ERN--GMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPG---LEGFP 871 ER G++ L KG GP G PGP G PG G PG G+PG + G P Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773 Query: 872 GVKGDRG---------------------PAGPPGIAGMSGKPGAPGPPGV---------P 901 G KGDRG P GPPG AG +G+ G PGP G+ P Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833 Query: 902 GEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRG---PKGERGDQGIP 958 G GE GP G +GF GP+GP G+PG+ G+ G PG +G G PG +G G G G+P Sbjct: 834 GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893 Query: 959 GDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEI 1018 G +G +G +G PG TG G+ G +GPPG G+ G G G PG G PG+ D S + Sbjct: 894 GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953 Query: 1019 KKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG 1078 + PA G G PG+DG PGP G PGP G G Sbjct: 954 GD---------------------RGPAGPPGGP--GDKGDPGEDGQPGPDGPPGPAGTTG 990 Query: 1079 QKG------ERGEPGI-GLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 Q+G +RGE G+ GLPG G PG T A G G PG GP G GP G PE Sbjct: 991 QRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPE 1049 Score = 593 bits (1530), Expect = e-169 Identities = 382/973 (39%), Positives = 465/973 (47%), Gaps = 188/973 (19%) Query: 291 KGEAGL----PGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG 346 KGE GL G G PG G G G G G G PG +G QG +G G G+ G G Sbjct: 115 KGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPG 174 Query: 347 EKGDPA--------------LAGLNGENGL----------KGDLGPHGPPGPKGEKGDTG 382 G P+ +AGL+ ++GL G +GP GP G +G++G G Sbjct: 175 PPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAG 234 Query: 383 PPGPPALPGS------LGIQGPQGPPGKEGQRGRRGKTGPPGK------PGPPGPPGPPG 430 P GPP PG +G +GP+GPPGK G+ G G+ G PG+ PG G PG PG Sbjct: 235 PTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPG 294 Query: 431 IQGI-----HQTLGGYYNKDNKGNDEHEAG--------------------------GLKG 459 + G+ H+ L G + + EAG G G Sbjct: 295 LPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPG 354 Query: 460 DKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIG 519 +G G+PG PG +GP G G G P G KG+ G G G +G +G+ G+ GPPG +G Sbjct: 355 QRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG 414 Query: 520 SPGL------------KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--- 564 SPGL KG GS G+ GP G G G PG G G QGI+G+ GDPG Sbjct: 415 SPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPG 474 Query: 565 --GIIGPPGLPGP---KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619 G GP G PGP +G GPPG+ G+ G G+PG GP GP GERG PG G PG Sbjct: 475 FKGEAGPKGEPGPHGIQGPIGPPGEE--GKRGPRGDPGTVGPPGPVGERGAPGNRGFPGS 532 Query: 620 ---IGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK------ 669 GP+G G G G+ GP G G G G PGLPG G GN GV G +GK Sbjct: 533 DGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGA 592 Query: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNK------GEEGGAGEPGKYD 723 PG G PG P ++ + G G++ +PG K + GE G AG PG+ Sbjct: 593 PGEDGRPGPPGSIGIRGQPGSM----------GLPGPKGSSGDPGKPGEAGNAGVPGQRG 642 Query: 724 SMARKGDIGPRGPPGIP---------GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPG 774 + + G++GP GP G P G GP G +G G PG PGE G G QG+PG PG Sbjct: 643 APGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPG 702 Query: 775 APGPTGPPGLM---GRTGHPGPTGAKGEK------GSDGPPGKPGPPGPPGIPFNERNGM 825 A GP GP G G G PG TG GEK G DGP G PGP G PG G Sbjct: 703 AVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPG-----DTGP 757 Query: 826 SSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGI 885 L +P G G PGPKGD G +GE GA G G +G G+ G GP GP G Sbjct: 758 PGLQ------GMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811 Query: 886 AGMSGKP------GAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 G G+P G PG G PG GE GP G +GF GP+GP G+PG+ G+ G PG +G Sbjct: 812 TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD 871 Query: 940 MGKPGDR---GPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH 996 G PG + G G G G+PG +G +G +G PG TG G+ G +GPPG G+ G G Sbjct: 872 AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931 Query: 997 QGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRP 1056 G PG G PG+ D S + + PA G Sbjct: 932 LGEPGKEGPPGLRGDPGSHGRVGD---------------------RGPAGPPGGP--GDK 968 Query: 1057 GPPGKDGLPGPPGDPGPQGYRGQK------GERGEPGI-GLPGSPGLPG-TSALGLPGSP 1108 G PG+DG PGP G PGP G GQ+ G+RGE G+ GLPG G PG G G Sbjct: 969 GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028 Query: 1109 GAPGPQGPPGPSG 1121 G PGP GPPG +G Sbjct: 1029 GPPGPVGPPGSNG 1041 Score = 593 bits (1530), Expect = e-169 Identities = 379/931 (40%), Positives = 451/931 (48%), Gaps = 129/931 (13%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGE---------------QGFEGSK 336 G G PGAPG PG KGH+G G G G G PG KGE +G G + Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGER 344 Query: 337 GETGEKGEQGEKGD---------------PALAGLNGENGLKGDLGP---HGPPGPKGEK 378 G G +G G++G P +G G G+KG+ GP GP GP+G++ Sbjct: 345 GRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQR 404 Query: 379 GDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTL 438 G+TGPPGP PG G G G PG +G G G +GPPG GPPG PGP G G Sbjct: 405 GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQ--- 461 Query: 439 GGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQ------KGEPGEPFTKGEKG 492 G++G G+ G+PGF G GPKG+ +G G P +G++G Sbjct: 462 -----------------GIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRG 504 Query: 493 DRGEPGVIGSQGVKGEPGDPGPPGLIGSPGL------KGQQGSAGSMGPRGPPGDVGLPG 546 RG+PG +G G GE G PG G GS GL +G++G GS GP+G GD G PG Sbjct: 505 PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564 Query: 547 EHGIPGKQGIKGEKG--DPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGP 604 E G+PG +G+ G G P G +GP G PG G GPPG G G G+ G PGP+G Sbjct: 565 EPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI--GIRGQPGSMGLPGPKGS 622 Query: 605 KGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG---TPGN 660 G+ G PG G+ G G +G G G G GP G PG+ G RG G PG G PG Sbjct: 623 SGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGP 682 Query: 661 DGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPG 720 G PG GKPG G PGDP A+ LG G N + + GL KG GG G G Sbjct: 683 PGPPGEGGKPGDQGVPGDPGAVGPLGPRGER-GNPGERGEPGITGLPGEKGMAGGHGPDG 741 Query: 721 KYDSMARKGDIGPRGPPGI---PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPG 777 S G G GPPG+ PG G G+ G +G G GEKG EG G G G PG Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPG 801 Query: 778 PTGPPGLMGRTGH---PGPTGAKGEKGSDGPPGKPGPPGPPG-IPFNERNGMSSLYKIKG 833 P GPPG G TG PGP G G GS G PG G GP G + F G +KG Sbjct: 802 PLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKG 861 Query: 834 GVNVPSY------PGP------PGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAG 881 P PGP PGP GP G PG G G G PG GFPG G GP G Sbjct: 862 EPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921 Query: 882 P---PGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGA-- 936 P PG AG G+PG GPPG+ G+PG G VGD G GP G G G G+DG PG Sbjct: 922 PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981 Query: 937 ----------QGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPG 986 +GI+G PG RG ERG G+PG G+ G+ G G TG KG GP+GPPG Sbjct: 982 PPGPAGTTGQRGIVGMPGQRG---ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG 1038 Query: 987 NKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAA 1046 + G +G PG +GP G+ G PG D E + + + P Sbjct: 1039 SNGPVGEPGPEGPAGNDGTPG--RDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD 1096 Query: 1047 MLAAQ-----AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-------IGLPGSP 1094 A Q + G GPPG+ G G PG GP+G +G G+RG+ G GL G P Sbjct: 1097 --AGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP 1154 Query: 1095 GLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125 G PG + G GS G PGP GP GP G P Sbjct: 1155 GPPGPN--GEQGSAGIPGPFGPRGPPGPVGP 1183 Score = 569 bits (1467), Expect = e-162 Identities = 353/852 (41%), Positives = 432/852 (50%), Gaps = 120/852 (14%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG------EKGE 344 +G+ G PG PG G+ G KGEPG +G+ G G PG++G++G G G G E+G Sbjct: 464 RGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGA 523 Query: 345 QGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 G +G P GL G G +G+ GP G GPKG +GD G PG P LPG+ G+ G PG Sbjct: 524 PGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN---PGV 580 Query: 405 EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEA-GGLKGDKGE 463 +G G+ G G PG+ G PGPPG GI+G ++G K + G+ G G G+ Sbjct: 581 QGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQ 640 Query: 464 TGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGL 523 G PG G VGP G G PG GE+G++G PG G QG+ PG PGPPG G PG Sbjct: 641 RGAPGKDGEVGPSGPVGPPG---LAGERGEQGPPGPTGFQGL---PGPPGPPGEGGKPGD 694 Query: 524 KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGI--IGPPGLPGPKG---E 578 +G G G++GP GP G+ G PGE G PG G+ GEKG GG GP G PGP G + Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754 Query: 579 AGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIG-PQGIGIPGRTGAQGP 636 GPPG + +PGE G+ G PG G RG GE+G G G+ G G P +G PG G G Sbjct: 755 TGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGE 814 Query: 637 AGEPGIQGPRGLPGLPGTPGTPGNDGVPGR---------DGKPGLPGPPGDPIALPLLGD 687 GEPG +G G PG G PG+ G +G G DG+PG+ G PG+P G Sbjct: 815 KGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874 Query: 688 IG--ALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGI------ 739 G L + + VPGLK +G +G G G S R G GP G PG Sbjct: 875 PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGE 934 Query: 740 PGREGPKGSKGERGYPGIPGEKGDEGL------QGIPGIPGAPGPTGPPGLMGRTGHPGP 793 PG+EGP G +G+ G G G++G G +G PG G PGP GPPG G TG G Sbjct: 935 PGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGI 994 Query: 794 TGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDP 853 G G++G G PG PGP G PG + G + KG P GPPG GP G+P Sbjct: 995 VGMPGQRGERGMPGLPGPAGTPG-----KVGPTGATGDKGP---PGPVGPPGSNGPVGEP 1046 Query: 854 GPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDI 913 GP G G G PG +G G +GDRG GP G+ G G PG PGP G PG+ G+RG Sbjct: 1047 GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGD---- 1102 Query: 914 GFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLT 973 PG GP G PG GK G+PG P+G RGD+G GDRG +G++G G T Sbjct: 1103 --PGSRGPIGPPGRAGKRGLPG------------PQGPRGDKGDHGDRGDRGQKGHRGFT 1148 Query: 974 GMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 G++G GP GP G +GS G PG GP G PG G Sbjct: 1149 GLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVG-------------------------- 1182 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGLPGS 1093 G+ G PG G GPPG G G G +G GEP G PG Sbjct: 1183 ------------------PSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP--GPPGP 1222 Query: 1094 PGLPG--TSALG 1103 PG PG T+ALG Sbjct: 1223 PGPPGHLTAALG 1234 Score = 473 bits (1216), Expect = e-133 Identities = 308/755 (40%), Positives = 350/755 (46%), Gaps = 101/755 (13%) Query: 448 GNDEHEAGGLKGDKGE-------TGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVI 500 G + + G KG KGE TG+ G PG GP G +G GE KG G RG G+ Sbjct: 102 GGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGID 161 Query: 501 GSQGVKGEPGDPGPPGLIGSPGLKGQQ----------------GSA-----GSMGPRGPP 539 G GV G+PG PGPPG PG G GS GS+GP GP Sbjct: 162 GEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR 221 Query: 540 GDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAP 599 G GL G+ G G G GE GDPG + GP G GP+G G PG+ GEPG +GNPG Sbjct: 222 GPQGLQGQQGGAGPTGPPGEPGDPGPM-GPIGSRGPEGPPGKPGED--GEPGRNGNPGEV 278 Query: 600 GPRGPKGERGLPGVHGSPGDIGPQG----------IGIPGRTGAQGPAGEPGIQGPRGLP 649 G G G RG PG G PG G +G +G PG G GP G G GP G Sbjct: 279 GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338 Query: 650 GLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSN 709 G+PG G G G PG+ G G+PG PG L + G G F GN PG+K Sbjct: 339 GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSG-----FPGN-----PGMKGE 388 Query: 710 KGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGI 769 G G G G G GP G PG+PG G G+ G +G G PG G G G Sbjct: 389 AGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGP 448 Query: 770 PGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLY 829 PG PG G TGP G+ G+ G PG G KGE G G PG G GP G P E Sbjct: 449 PGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR----- 503 Query: 830 KIKGGVNVPSYPGPPGPPGPKGDPGPVGE---PGAMGLPGLEGFPGVKGDRGPAGPPGIA 886 GP G PG G PGPVGE PG G PG +G PG KG +G GP G + Sbjct: 504 ------------GPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSS 551 Query: 887 GMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEG---PSGKPGINGKDGIPGAQGIMGKP 943 G G G PG PG PG PG RG G+ G GPEG P G PG +G+ G PG+ GI G+P Sbjct: 552 GPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP 611 Query: 944 GDRG---PKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPP 1000 G G PKG GD G PG+ G+ G G+ G G G +GP GP G G G G QGPP Sbjct: 612 GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEV---------LRIFEER----MAVFLSQLKLPAAM 1047 G G G+P E K +Q V L ER LP Sbjct: 672 GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEK 731 Query: 1048 LAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERG----------EPGIGLPGSPGLP 1097 A +G GP G G G PGD GP G +G GERG GIG G+ G Sbjct: 732 GMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTA 791 Query: 1098 GTS-ALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 G A GLPG G PGP GP G G P + P Sbjct: 792 GNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGP 826 Score = 372 bits (955), Expect = e-102 Identities = 250/651 (38%), Positives = 295/651 (45%), Gaps = 117/651 (17%) Query: 535 PRGPPGDV-----GLPGEHGIPGKQGIKGEKGDPG------------GIIGPPGLPGPKG 577 P PPG+ PG +G KG+KG+PG G GPPG GP+G Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 578 EAGPPGKSLP-GEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGP-----------QGI 625 E GP G+ P G G+DG PG PG G G G P G G P G+ Sbjct: 145 ERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGL 204 Query: 626 G-----IPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPI 680 G +PG G GP G G+QG +G G G PG PG+ G G G G GPPG P Sbjct: 205 GSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKP- 263 Query: 681 ALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIP 740 G+ G PG N GE G AG PG +G G G PG+ Sbjct: 264 -----GEDGE-------------PGRNGNPGEVGFAGSPGA------RGFPGAPGLPGLK 299 Query: 741 GREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEK 800 G G KG +G +G G PG KG+ G G G A GP GP G+ G G GP GA G++ Sbjct: 300 GHRGHKGLEGPKGEVGAPGSKGEAGPTGPMG---AMGPLGPRGMPGERGRLGPQGAPGQR 356 Query: 801 GSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD---PGPVG 857 G+ G PGKPGP GP GIP + +G +KG GP GP G +G+ PGPVG Sbjct: 357 GAHGMPGKPGPMGPLGIPGS--SGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG 414 Query: 858 EPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPG 917 PG G G +G PG KG G G G G +G PG+PGP G G G RG GD G PG Sbjct: 415 SPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPG 474 Query: 918 ------PEGPSGKPGINGKDGIPGAQGIMGK---PGDRGPKGERGDQGIPGDRGSQGERG 968 P+G G GI G G PG +G G PG GP G G++G PG+RG G G Sbjct: 475 FKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534 Query: 969 KPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLR 1028 PG G +G GP+G G KGS G PG G PG PG G+ + Sbjct: 535 LPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN----------------- 577 Query: 1029 IFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI 1088 P G G PG+DG PGPPG G RGQ G G PG Sbjct: 578 ---------------PGVQGPEGKLGPLGAPGEDGRPGPPGSIG---IRGQPGSMGLPGP 619 Query: 1089 -GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHAHQR 1138 G G PG PG + G+ G PG +G PG G P + P A +R Sbjct: 620 KGSSGDPGKPGEA-----GNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGER 665 Score = 315 bits (808), Expect = 1e-85 Identities = 199/464 (42%), Positives = 227/464 (48%), Gaps = 41/464 (8%) Query: 290 NKGEAGLPGA---PGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQG 346 N G GLPG PG G G KGEPG GL G PG G G +G G G G G QG Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQG 852 Query: 347 EKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEG 406 G P + G GE G KGD G PGP+G G GP GP +PG G +G QGPPG G Sbjct: 853 PDGQPGVKGEPGEPGQKGDAGS---PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATG 909 Query: 407 QRGRRGKTGPPGKPGPPGPPGP---PGIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDK 461 G G+ GPPG G PGP GP PG +G L G + D AG G GDK Sbjct: 910 FPGSAGRVGPPGPAGAPGPAGPLGEPGKEG-PPGLRGDPGSHGRVGDRGPAGPPGGPGDK 968 Query: 462 GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSP 521 G+ G G PG GP G G G+ G G RGE G+ G G G PG GP G G Sbjct: 969 GDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDK 1028 Query: 522 GLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGP 581 G G G GS GP G PG G G G PG+ G GE+GD G GP GLPG +G G Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGD-PGPAGLPGSQGAPGT 1087 Query: 582 PGK-SLPGEPGLDGNPGAPGPRGP---KGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPA 637 PG PG+ G G+PG+ GP GP G+RGLPG G GD G G G +G Sbjct: 1088 PGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH-----GDRGDRGQK 1142 Query: 638 GEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCG 697 G G G +GLPG PG G G+ G+PG G G PGP G G +G + Sbjct: 1143 GHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPI------ 1196 Query: 698 NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPG 741 PG++ + GE G G P G+ GP GPPG PG Sbjct: 1197 ----GPPGVRGSVGEAGPEGPP---------GEPGPPGPPGPPG 1227 Score = 227 bits (579), Expect = 4e-59 Identities = 133/316 (42%), Positives = 154/316 (48%), Gaps = 44/316 (13%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347 + ++G AG PG PG G G G+PG +G G G GQ+G G G +GE G G G Sbjct: 953 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGP 1012 Query: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 G P G G G KG GP GPPG G G+ GP GP G+ G G G G G Sbjct: 1013 AGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGD 1072 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G G G G PG PGP G P GD G+ G P Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAP-----------------------------GDAGQRGDP 1103 Query: 468 GFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQ 527 G G +GP G+ G+ G P +G +GD+G+ G G +G KG G G GL G PG G+Q Sbjct: 1104 GSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQ 1163 Query: 528 GSA---GSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGK 584 GSA G GPRGPPG VG G+ G PG P G IGPPG+ G GEAGP G Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPG----------PLGPIGPPGVRGSVGEAGPEGP 1213 Query: 585 SLPGEPGLDGNPGAPG 600 PGEPG G PG PG Sbjct: 1214 --PGEPGPPGPPGPPG 1227 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 593 bits (1529), Expect = e-169 Identities = 392/943 (41%), Positives = 458/943 (48%), Gaps = 158/943 (16%) Query: 285 CQCIPNKGEAGLPGAPGSPGQKGHKGE---PGENGLHGAPGFPGQKGEQGFEGSKGETGE 341 C C P G G PG PG PG++G KG+ PG G G PG PG +G G G G +G Sbjct: 492 CACEP--GPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGP 549 Query: 342 KGEQGEKGDPALAGLNGENGLKGDLGP---------HGPPGPKGEKGDTGPPGP--PALP 390 G +G KGD ++ + G G +G GP HG G GEKGD GPPG A P Sbjct: 550 PGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATP 609 Query: 391 GSLGIQGPQGPPGKEGQRGRRGK--TGPPGKPGPPGPPGPPGIQG-------------IH 435 G G GP GPPGK G G G GPPG+ G PG PG PG++G + Sbjct: 610 GGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCN 669 Query: 436 QTLGGYYNKDNKGNDEHEAG--------GLKGDKGETGLPGFPGSV---GPKGQKGEPGE 484 T G + G GL G G G PG PG+ GP G +G+ G+ Sbjct: 670 VTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGD 729 Query: 485 PFTKGEKGDR--GEPGVIGSQGVKGEPGDPGPP--GLIGSPGLKGQQGSAGSMGPRGPPG 540 P GEKG G PG GS GV G+ G PG P G +G PG +G G G GPRG PG Sbjct: 730 PGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPG 789 Query: 541 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKG---EAGPPGKSLPGEPGLDGNPG 597 G G GIPG G+KG KG G G PG+PGP G E G PG +PG+PGL G PG Sbjct: 790 CPGAEGPAGIPGFLGLKGPKGREGHA-GFPGVPGPPGHSCERGAPG--IPGQPGLPGYPG 846 Query: 598 APGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG 656 +PG G KG+ PG G PG G +G+ G+PGR GA GP G PGI GP G GLPG PG Sbjct: 847 SPGAPGGKGQ---PGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPG 903 Query: 657 TPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGA 716 G G+PG G PG G PG G+ G K G +PG + +G +G Sbjct: 904 PKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGE--KGMSG-----LPGDRGLRGAKGAI 956 Query: 717 GEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIP-GA 775 G PG MA G G PG PG +G G +G++G PG+ G +G+ G G PG G Sbjct: 957 GPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGE 1016 Query: 776 PGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGV 835 PG G PG G G PG TG +G G G PG G PG PG P G S + +G Sbjct: 1017 PGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPP-----GFSGIDGARGPK 1071 Query: 836 NVPSYPGPP-GPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA 894 P GPPGPKG+PG G PG G G +G PG++G RG G PG G SG PG Sbjct: 1072 GNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGC 1131 Query: 895 PGPPGVPG---------EPGERGPVGDIGFPGP---EGPSGKPGINGKDGIPGAQGIMGK 942 PG G+PG +PG RG GD G PGP +GPSG PG+NG G+ G +G G Sbjct: 1132 PGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGA 1191 Query: 943 PG--DRGP---------KGERGDQGIPG--DRGSQGERGKPGLTGMKGAIGPMGP----- 984 G D GP KGERGD G PG G +G++G PG G G GP G Sbjct: 1192 SGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAP 1251 Query: 985 -----PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLS 1039 PG G G PG GP G+PG PG+P ++LR Sbjct: 1252 KDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSV------------DLLR----------- 1288 Query: 1040 QLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRG---------QKGERGEPGIGL 1090 G PG G G PGPPG PGP GY+G QKG G PG Sbjct: 1289 --------------GEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQG 1334 Query: 1091 P-GSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP----EDC 1128 P G PG PG GLPG PG GP G PGP G P +DC Sbjct: 1335 PHGFPGPPGEK--GLPGPPGRKGPTGLPGPRGEPGPPADVDDC 1375 Score = 572 bits (1475), Expect = e-163 Identities = 395/1049 (37%), Positives = 474/1049 (45%), Gaps = 252/1049 (24%) Query: 285 CQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGE 344 C C+P KG G PG PG G G G PG GL G +KG +G G G G+KG+ Sbjct: 55 CHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSG------EKGMRGDRGPPGAAGDKGD 108 Query: 345 QGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGK 404 +G G P GL+G G G GP G PG G G G PG P G+LG GP G PG+ Sbjct: 109 KGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGE 168 Query: 405 EGQRGR--------------------------------RGKTGPPGKP---GPPGPPGPP 429 +G++G G TG PG+P GPPG PG P Sbjct: 169 KGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRP 228 Query: 430 GIQ-----GIHQTLGGYYNKDNKGND--------------EHEAG--------------G 456 G++ G+ +G +G+ + E G G Sbjct: 229 GLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPG 288 Query: 457 LKGD-----KGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD 511 KG+ KGE G+PGFPG G G G PG P KGE G G+PG+ G G KG+PG+ Sbjct: 289 RKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGN 348 Query: 512 ---PGPPGLI-----------GSPGLKGQQGSAGSMGPRGPPGDVGLPGE---------- 547 PGPPG++ G PG G+ G G +GP GPPG +G PGE Sbjct: 349 RGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPG 408 Query: 548 -HGIPGKQGIKGEKGDPG---------GIIGPPGLPGPKGEAGPPGKSL-------PGEP 590 G PG G+ GE G PG G G PGLPG G G PG S+ PG Sbjct: 409 PQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQ 468 Query: 591 GLDGNPGAPGPRGPKGERGLPGVHG-SPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGL 648 G+ G G PG RGPKGE+G G+ PG +GP G G+PGR G++G G PG G +G Sbjct: 469 GIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGD 528 Query: 649 PGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGAL----LKNFCGNCQASVP 704 PG PG G PG G G G PG G GD + + G G F G Q Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG--QPGSH 586 Query: 705 GLKSNKGEEGGAGEPGKYD--SMARKGDIGPRGPPGIPGREGP-----KGSKGERGYPGI 757 G + GE+G G PG ++ + KG GP GPPG G GP G GERG+PG+ Sbjct: 587 GRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGV 646 Query: 758 P------------GEKGD--------------EGLQGIPGIPGAPGPTGPPGLMGRTGH- 790 P G+KGD G G PG G PGP G PGL G GH Sbjct: 647 PGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHK 706 Query: 791 -----------PGPTGAKGEKGSDG--------PPGKPGPPGPPGIPFNE---------- 821 PGP G +G+ G G P G PGPPG PG+ + Sbjct: 707 GRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGH 766 Query: 822 -----RNGMSSLYKIKGGVNVPSYPGPPGP---PGPKGDPGPVGEPGAMGLPGLEGFPGV 873 + G+S + IKG P PG GP PG G GP G G G PG+ G PG Sbjct: 767 LGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGH 826 Query: 874 KGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGI 933 +RG G PG G+ G PG+PG PG G+PG+ GP G G G G G+PG +G G+ Sbjct: 827 SCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGL 886 Query: 934 PGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 PG G G G GP G +G +G+PG G GERGKPG G GA G PG KG G Sbjct: 887 PGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGA---KGEPGEKGMSGL 943 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 PG +G G+ G G P D E MA+ +SQ P Sbjct: 944 PGDRGLRGAKGAIGPPGD-------------------EGEMAI-ISQKGTP--------- 974 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGE----------RGEPG----IGLPGSPGLPGT 1099 G PGPPG DG PG GD G G +G++GE RGEPG G PG PG PG+ Sbjct: 975 GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS 1034 Query: 1100 SAL-------GLPGSPGAPGPQGPPGPSG 1121 + L GLPG G PG GPPG SG Sbjct: 1035 TGLRGFIGFPGLPGDQGEPGSPGPPGFSG 1063 Score = 572 bits (1475), Expect = e-163 Identities = 383/947 (40%), Positives = 429/947 (45%), Gaps = 174/947 (18%) Query: 280 ELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPG--ENGLHGAPGFPGQKGEQGFEGSKG 337 E D C KG G+PG G PG G KGE G G G PGFPG +G+ G GS G Sbjct: 261 EPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPG 320 Query: 338 ETGEKGEQGEKGDPALAGLNGENG--------------------LKGDLGPHGPPGPKGE 377 G KGE G GDP L GL G G LKG G G PG GE Sbjct: 321 FPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGE 380 Query: 378 KGDTGPPGPPAL--------PGSLGIQGPQGPPGKEGQRGRRG-------KTGPPGKPGP 422 GD GPPGPP L G +G GPQG PG G G G G PGKPG Sbjct: 381 TGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGS 440 Query: 423 PGPPGPPGIQGIHQTLGGYYNKDNKGND--EHEAG--GLKGDKGETGLPGFPG-SVGPKG 477 PG PG PG+QG+ + Y + N G + + G G +G KGE G G GP G Sbjct: 441 PGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMG 500 Query: 478 QKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGP-- 535 G PG P +G KGD G PG +G++G G PG GPPGL G G G G+ G+ G Sbjct: 501 PPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMV 560 Query: 536 ----------RGPPGDVGLPGEHGIPGKQGIKGEKGDPG-------------GIIGPPGL 572 RGP G G PG+ G G+ G GEKGDPG G GP G Sbjct: 561 VSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGP 620 Query: 573 PGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTG 632 PG G GPPG PG PG G+PG PG G +G GL G GD + PGR Sbjct: 621 PGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKG---QKGDTISCNVTYPGR-- 675 Query: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692 GP G G GP+G PG G PG G+DG GR G PG PG P Sbjct: 676 -HGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPP------------- 721 Query: 693 KNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGER 752 G + + G+ G GE G +GP GPPG PG G KG G+ Sbjct: 722 ------------GFRGDMGDPGFGGEKGS-------SPVGPPGPPGSPGVNGQKGIPGDP 762 Query: 753 GYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPP 812 + G G G GL G+PGI G G G PG G G PG G KG KG +G G PG P Sbjct: 763 AF-GHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVP 821 Query: 813 GPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPG 872 GPPG ER I G +P YPG PG PG KG PG VG PG G+ GL G PG Sbjct: 822 GPPGHSC-ERGAPG----IPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPG 876 Query: 873 VKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDG 932 G GP G PGI G G G PGPPG G RG G GFPG G G G G G Sbjct: 877 RPGAHGPPGLPGIPGPFGDDGLPGPPG---PKGPRGLPGFPGFPGERGKPGAEGCPGAKG 933 Query: 933 IPGAQGIMGKPGDRGPKGERGDQGIPGD---------RGSQGERGKPGLTGMKGAIGPMG 983 PG +G+ G PGDRG +G +G G PGD +G+ GE G PG G G G G Sbjct: 934 EPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKG 993 Query: 984 PPGNKGSMGSPGHQGPP----------GSPGIPGIPADAVSFEEIKKYINQEVLRIFEER 1033 PG +G G PG GPP G PG PG P S LR F Sbjct: 994 TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS----------TGLRGF--- 1040 Query: 1034 MAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----- 1088 + P G PG G+ G PGPPG G G RG KG +G+P Sbjct: 1041 -------IGFP---------GLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP 1084 Query: 1089 ---GLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSGRCNPEDC 1128 G PGSPG PG + GLPG G G G PGP G P C Sbjct: 1085 GPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGC 1131 Score = 568 bits (1464), Expect = e-161 Identities = 383/955 (40%), Positives = 440/955 (46%), Gaps = 204/955 (21%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGE--------NGLHGAPGFPGQK 327 P LK + + + G GL G G PG +GH G PG G G PGFPG+ Sbjct: 319 PGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRY 378 Query: 328 GEQGFEGSKGETGEKGEQGE-----------KGDPALAGLNGENGLKGDLGPHGPPGPKG 376 GE G G G G G GE +G P L GL GE G+ G P PG G Sbjct: 379 GETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPG--RPDSAPGKPG 436 Query: 377 EKGDTGPPGPPAL---------------PGSLGIQGPQGPPGKEGQRGRRGKTG----PP 417 + G G PG P L PG GI+G GPPG G +G +G G P Sbjct: 437 KPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEP 496 Query: 418 GKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKG 477 G GPPGPPG PG QG +KG+ GL G G G PG PG+ GP G Sbjct: 497 GPMGPPGPPGLPGRQG------------SKGD-----LGLPGWLGTKGDPGPPGAEGPPG 539 Query: 478 QKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRG 537 G+ G G KG +G+ V +G KGE G GPPG G PG G+ G AG G G Sbjct: 540 LPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG 599 Query: 538 PPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGN 595 PPGD E PG +G G G PG G +GPPGL G GPPG+ G PG+ G+ Sbjct: 600 PPGD----HEDATPGGKGFPGPLGPPGKAGPVGPPGL----GFPGPPGER--GHPGVPGH 649 Query: 596 PGAPGPRGPKGERG--------LPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRG 647 PG GP G KG++G PG HG PG GP PG G GP G PG+ G G Sbjct: 650 PGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGP-----PGPKGFPGPQGAPGLSGSDG 704 Query: 648 LPGLPGTPGT---PGNDGVPGRDGKPGL-----------PGPPGDP--------IALPLL 685 G PGTPGT PG G G G PG PGPPG P P Sbjct: 705 HKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAF 764 Query: 686 GDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGP 745 G +G K + VPG+K +G+ G G GP G PG G +GP Sbjct: 765 GHLGPPGKRGL----SGVPGIKGPRGDPGCPGAE------------GPAGIPGFLGLKGP 808 Query: 746 KGSKGERGYPGIPG------EKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE 799 KG +G G+PG+PG E+G G+ G PG+PG PG G PG G+ G GP G G Sbjct: 809 KGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 868 Query: 800 KGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEP 859 KG G PG+PG GPPG+P I G PGPPGP GP+G PG G P Sbjct: 869 KGLPGLPGRPGAHGPPGLP-----------GIPGPFGDDGLPGPPGPKGPRGLPGFPGFP 917 Query: 860 GAMGLPGLEGFPGVK---GDRGPAGPPGIAGMSGKPGAPGPPGVPGE---------PGER 907 G G PG EG PG K G++G +G PG G+ G GA GPPG GE PGE Sbjct: 918 GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP 977 Query: 908 GPVGDIGFPGPEGPSGKPGINGKDGIP----------GAQGIMGKPGDRGPKGE------ 951 GP GD GFPG G G PG+ G+ G P G G G+PG GP G Sbjct: 978 GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL 1037 Query: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGS----MGSPGHQGPPGSPGIPG 1007 RG G PG G QGE G PG G G G GP GNKG G PG +G PGSPG PG Sbjct: 1038 RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPG 1097 Query: 1008 IPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGP 1067 + + LP + GRPGPPG G PG Sbjct: 1098 HFGAS--------------------------GEQGLPGIQGPRGSPGRPGPPGSSGPPGC 1131 Query: 1068 PGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 PGD G G RGQ GE G+PG GL G P G+PG PG GP G PG +G Sbjct: 1132 PGDHGMPGLRGQPGEMGDPGPRGLQGDP--------GIPGPPGIKGPSGSPGLNG 1178 Score = 392 bits (1008), Expect = e-109 Identities = 266/654 (40%), Positives = 321/654 (49%), Gaps = 81/654 (12%) Query: 524 KGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPG 583 KG +G G GP+GP G +G PG G+ G++G++G++G PPG G KG+ GP G Sbjct: 61 KGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRG-------PPGAAGDKGDKGPTG 113 Query: 584 KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD---------IGPQG-IGIPGRTGA 633 +PG PGLDG PG PGP GP+G+ G+ G +GS GD +GP G +G PG G Sbjct: 114 --VPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGE 171 Query: 634 QGPA-----GEPGIQGPRGLPGLPGTPGT---PGNDGVPGRDGKPGLPGPPGDPIALPLL 685 +G + GIQG RG PGLPG PG+ G G G G+PGL GPPG P L Sbjct: 172 KGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLK 231 Query: 686 GDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKY------DSMARKGDIGPRGPPGI 739 G+ G V G + GE G G PG D KG+ G +G PG+ Sbjct: 232 GNPGV-----------GVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGM 280 Query: 740 PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGE 799 G GP G KGE G G GEKG G G G PG+ G G PGL G G G G G Sbjct: 281 VGLPGPPGRKGESGI-GAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGL 339 Query: 800 KGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEP 859 G G PG G PGPPG+ ++ +KG P PG PG G GD GP G P Sbjct: 340 IGPKGDPGNRGHPGPPGVL------VTPPLPLKGP---PGDPGFPGRYGETGDVGPPGPP 390 Query: 860 GAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPG-PPGVPGEPGERGPVGDIGFPGP 918 G +G PG E G+ G GP G PG+ G+ G+ G PG P PG+PG+ G G G PG Sbjct: 391 GLLGRPG-EACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGL 449 Query: 919 EGPSGKPGINGKDGIPGAQGIMGK---PGDRGPKGERGDQGI----PGDRGSQGERGKPG 971 +G G I G PG QGI GK PG RGPKGE+G++G+ PG G G G PG Sbjct: 450 QGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPG 509 Query: 972 LTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFE 1031 G KG +G G G KG G PG +GPPG PG G + + V Sbjct: 510 RQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKG 569 Query: 1032 ERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD-----------PGPQGYRGQK 1080 ER P ++GR G G+ G PGPPGD PGP G G+ Sbjct: 570 ER-----GPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKA 624 Query: 1081 GERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSH 1134 G G PG+G PG PG G G+PG PG GP G G G + YP H Sbjct: 625 GPVGPPGLGFPGPPGERGHP--GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRH 676 Score = 353 bits (907), Expect = 4e-97 Identities = 230/560 (41%), Positives = 264/560 (47%), Gaps = 83/560 (14%) Query: 270 KMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGE 329 K S LP + L+ I G+ G G G G PG++ GFPG++G+ Sbjct: 938 KGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDD------GFPGERGD 991 Query: 330 QGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL 389 +G G +G GE G G G GE G KG GP GPPGP G G G G P L Sbjct: 992 KGTPGMQGRRGEPGRYGPPGFH-----RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGL 1046 Query: 390 PGSLGIQGPQGPPGKEGQRGRRGKTGPPGKP----GPPGPPGPPGIQGIHQTLGGYYNKD 445 PG G G GPPG G G RG G G P GPPGP G PG G G Sbjct: 1047 PGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFG------ 1100 Query: 446 NKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGV 505 + E G++G +G G PG PGS GP G G+ G P +G+ G+ G+PG G QG Sbjct: 1101 --ASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGD 1158 Query: 506 KGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPG--DVGLPGEHGIPGKQGIKGEKGDP 563 G PG PG G GSPGL G G G G +G G DVG PG GIPG +G +G+ G P Sbjct: 1159 PGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSP 1218 Query: 564 GGIIGPPGLPGPKGEAGPPGKSLP-----------------------GEPGLDGNPGAPG 600 G I PPG G KG GPPG S P G PG DG GAPG Sbjct: 1219 G--ISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPG 1276 Query: 601 P----------RGPKGERGLPGVHGSPGDIGPQGI----GIPGRTGAQGPAGEPGIQGPR 646 P RG G+ GLPG G PG GP G G G+ G +GP G PG QGP Sbjct: 1277 PPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPH 1336 Query: 647 GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGL 706 G PG PG G P G PGR G GLPGP G+P + D + +PG Sbjct: 1337 GFPGPPGEKGLP---GPPGRKGPTGLPGPRGEPGPPADVDDCPRI---------PGLPGA 1384 Query: 707 KSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGL 766 +G EG G PG +G GP G G PG +G +G G G PG PG KGD G Sbjct: 1385 PGMRGPEGAMGLPG------MRGPSGP-GCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGE 1437 Query: 767 QGIPGIPGAPGPTGPPGLMG 786 G PG PG PGP G PG G Sbjct: 1438 DGYPGGPGPPGPIGDPGPKG 1457 Score = 280 bits (716), Expect = 6e-75 Identities = 192/505 (38%), Positives = 232/505 (45%), Gaps = 86/505 (17%) Query: 696 CGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP 755 CG SV KG G G PG +G IGP G PG G G KG +G+RG P Sbjct: 47 CGGRDCSVCHCVPEKGSRGPPGPPGP------QGPIGPLGAPGPIGLSGEKGMRGDRGPP 100 Query: 756 GIPGEKGDEGLQGIPG------IPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKP 809 G G+KGD+G G+PG IPG PGP GP G G +GH G G G G G G Sbjct: 101 GAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPG 160 Query: 810 GPPGPPGIPFNERNGMSSLYKIK------GGVNVPSYP------GPPGPPGPKGDPGPVG 857 GP G PG + N + L +K G +P P GP GP G G+PG VG Sbjct: 161 GPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVG 220 Query: 858 EPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKP---------------------GAPG 896 PG G PGL+G PGV G +G G PG G G P G PG Sbjct: 221 PPGQPGRPGLKGNPGV-GVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPG 279 Query: 897 PPGVPGEPGER-----GPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDR----- 946 G+PG PG + G G+ G PG GP G PG G G PG +G +G GD Sbjct: 280 MVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGL 339 Query: 947 -GPKGERGDQGIPGDRG--------SQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGH- 996 GPKG+ G++G PG G +G G PG G G G +GPPG G +G PG Sbjct: 340 IGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEA 399 Query: 997 -------QGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLA 1049 GP G PG+PG+P +A + + + LP + + Sbjct: 400 CAGMIGPPGPQGFPGLPGLPGEA-GIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVI 458 Query: 1050 AQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERG-EPG-IGLPGSPGLPGTSA----LG 1103 + G PGP G G GPPG GP+G +G +G EPG +G PG PGLPG LG Sbjct: 459 YCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLG 518 Query: 1104 LP------GSPGAPGPQGPPGPSGR 1122 LP G PG PG +GPPG G+ Sbjct: 519 LPGWLGTKGDPGPPGAEGPPGLPGK 543 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 592 bits (1526), Expect = e-169 Identities = 400/985 (40%), Positives = 468/985 (47%), Gaps = 179/985 (18%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGEN---------------GLHGAPGFPGQKGEQGFEGSK 336 G G PG PG PG KG KG+PG + GL G PG PG+KG +G+ G Sbjct: 658 GPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPA 717 Query: 337 GETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQ 396 G GE+G+ G +G P G G GL G P G PGPKG +G G PG LPGS G + Sbjct: 718 GHPGEQGQPGPEGSPGAKGYPGRQGLPG---PVGDPGPKGSRGYIGLPGLFGLPGSDGER 774 Query: 397 GPQGPPGKEGQRGRRG------KTGPPGKPGPPGP---PGPPGIQGIHQTLG-----GYY 442 G G PGK G+ G G + GPPG G PG PGPPG+ G+ LG GY Sbjct: 775 GLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYP 834 Query: 443 N-KDNKG-----------NDEHEAG--------GLKGDKGETGLPGFPGS---------V 473 K KG D+ E G G +GDKG GLPGFPG+ V Sbjct: 835 GPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKV 894 Query: 474 GPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG---------------------DP 512 G KG G PG P +G GD G PG G +G+KG+PG P Sbjct: 895 GDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPP 954 Query: 513 GPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHG---------IPGKQGIKGEKGDP 563 G PGL G PG KG G G G +G PGD G PG G + G+ GI GEKGD Sbjct: 955 GAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDR 1014 Query: 564 GGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQ 623 G ++GPPG+PGPKG G PG PG G PG PGP+GP G RG PG+ G+ G GP+ Sbjct: 1015 G-MMGPPGVPGPKGSMGHPGM-----PGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPR 1068 Query: 624 GI-------------------GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVP 664 G G PGR G QG AGE G G RG PG+PG G PG G+P Sbjct: 1069 GPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLP 1128 Query: 665 GRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDS 724 G G G GP G P + G GA+ + +PG KG+ G G PG+ Sbjct: 1129 GEPGPQGPQGPIGPPGEMGPKGPPGAV-------GEPGLPGEAGMKGDLGPLGTPGEQGL 1181 Query: 725 MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTG---P 781 + ++G+ G G G G +G KG +G+ G G GEKG EGL G G PG PG TG P Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241 Query: 782 PGLMGRTGHPGPTGAKGEKGSDGP------PGKPGPPGPPGIPFNERN-----GMSSLYK 830 G G+ G G TGAKG KG G PG PGPPG PG P R G Sbjct: 1242 EGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPG-PKGSRGSLGPTGAPGRMG 1300 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPG-LEGFPGVKGDRGPAGPPGIAGMS 889 +G + Y G G GP G PGP GE G G G EG PG GDRGP G G G Sbjct: 1301 AQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360 Query: 890 GKPGAPGPPGV------------PGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQ 937 G PG PG GV PG PG RG G G G EGP GK G G G G Q Sbjct: 1361 GDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQ 1420 Query: 938 GIMGKPGDRGPKGERGDQGI------PGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSM 991 G+ G PG RG G +G +GI PG G G++G+ G G G +GP G GN G Sbjct: 1421 GLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVA 1480 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G PG QGPPG G G+P + R E R + +Q + P + Sbjct: 1481 GLPGAQGPPGFKGESGLPGQ----------LGPPGKRGTEGRTGLPGNQGE-PGSKGQPG 1529 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG----------IGLPGSPGLPGTSA 1101 G G PG GL GP G PG G++G +G RG PG +G+ G GLPG Sbjct: 1530 DSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKG 1589 Query: 1102 -LGLPGSPGAPGPQGPPGPSGRCNP 1125 G G G GP+GPPGP GR P Sbjct: 1590 DKGSRGDWGLQGPRGPPGPRGRPGP 1614 Score = 573 bits (1477), Expect = e-163 Identities = 359/868 (41%), Positives = 429/868 (49%), Gaps = 124/868 (14%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETG---EKGEQGEK 348 G P G PG KG G PG GL G PG PG +G +G G G G G +G+K Sbjct: 616 GSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQK 675 Query: 349 GDPALAGLNGENGLKGDLGP---HGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKE 405 GDP L+ +G KGD+G G PGP G KG G PGP PG G GP+G PG + Sbjct: 676 GDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAK 735 Query: 406 GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETG 465 G GR+G PGP G PGP G +G + L G + GL G GE G Sbjct: 736 GYPGRQGL------PGPVGDPGPKGSRG-YIGLPGLF-------------GLPGSDGERG 775 Query: 466 LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKG 525 LPG PG +G+ G PG P G G+RG PG+ G+ G G PG PG PGLIG G+ G Sbjct: 776 LPGVPGK---RGKMGMPGFP---GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLG 829 Query: 526 QQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAG 580 G G G +G G VG PG G G+QG+ G GDPG G G PG PG +G+ G Sbjct: 830 PIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPG 889 Query: 581 PPGK-------SLPGEPGLDGNP---GAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGR 630 P GK PG PG +G P G PG GP+G +G PG G PG G G Sbjct: 890 PLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQL-----GP 944 Query: 631 TGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGA 690 G +GP G PG G G PG G PG PG DGV G G PG PGP G+ + +G +G Sbjct: 945 EGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVG- 1003 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 + + G K ++G G G PG SM G G G PG PG +GP GS+G Sbjct: 1004 ---------EPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRG 1054 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEK---GSDGPPG 807 G G G +G G G G G+ G GPPG GR G PG G GE+ GS G PG Sbjct: 1055 PPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114 Query: 808 KPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGL 867 PGP GPPG KG P GP GP GP G+ GP G PGA+G PGL Sbjct: 1115 IPGPSGPPG--------------TKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGL 1160 Query: 868 EGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE---GPSGK 924 G G+KGD GP G PG G+ G+ G PG G G G G GD G PGP+ G G+ Sbjct: 1161 PGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQ 1220 Query: 925 PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP 984 G+ G+DG PG G+ G G G G++G++G G +G++G +G+ G G+ G GP G Sbjct: 1221 EGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280 Query: 985 PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLP 1044 PG KGS GS G G PG G G P A ++ K + Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLA-GYDGHKGIVG--------------------- 1318 Query: 1045 AAMLAAQAYGRPGPPGK----------DGLPGPPGDPGPQGYRGQKGERGEPGIGLPGSP 1094 G PGP G+ +G PGPPGD GP G RG +GE G+P G PG Sbjct: 1319 -------PLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDP--GYPGQE 1369 Query: 1095 GLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 G+ G G G PG PGP+G PGP G Sbjct: 1370 GVQGLRGKPGQQGQPGHPGPRGWPGPKG 1397 Score = 523 bits (1347), Expect = e-148 Identities = 341/832 (40%), Positives = 397/832 (47%), Gaps = 134/832 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349 N GE GLPG PG PG G G G G G G G G G G KG+ GE+G G G Sbjct: 806 NPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSG 865 Query: 350 DPALAGLNGENGLKGDLGPHGPPGPKGEKGDTG------PPGPPALPGSLGIQGPQGP-- 401 DP G G GL G G G PGP G+ GD G PPGP PG +G G GP Sbjct: 866 DPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEG 925 Query: 402 ----PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG--GYYNKDNKGNDEHEAG 455 PG G G RG+ GP G GP GPPG PG++G G G D + + G Sbjct: 926 MKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPG 985 Query: 456 -----GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPG 510 G +G G GL G PG VG KG +G G P G KG G PG+ G G GEPG Sbjct: 986 RPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045 Query: 511 DPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG-----G 565 GPPG G PG++G +G G GP GP G+ G G G PG QG G G G G Sbjct: 1046 PQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERG 1105 Query: 566 IIGPPGLPGPKGEAGPPG-KSLPGEPGLDGN------PGAPGPRGPKG---ERGLPGVHG 615 +G G PG G +GPPG K LPGEPG G PG GP+GP G E GLPG G Sbjct: 1106 HLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAG 1165 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPGIQG---PRGLPGLPGTPGTPGNDGVPGRDGKPGL 672 GD+GP +G PG G G GEPG++G P G GL G G PG DG G G+ GL Sbjct: 1166 MKGDLGP--LGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGL 1223 Query: 673 ---PGPPGDPIALPLLGDIGAL-------------LKNFCGNC----------QASVPGL 706 GPPG P + G G K + G PG Sbjct: 1224 MGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGP 1283 Query: 707 KSNKGEEGGAGEPGKYDSMAR---------KGDIGPRGPPGIPGREGPKGSKGE-RGYPG 756 K ++G G G PG+ + KG +GP GPPG G +G +G G+ G PG Sbjct: 1284 KGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPG 1343 Query: 757 IPGEKG---DEGLQGIPGIPGAPGPTG------PPGLMGRTGHPGPTG---AKGEKGSDG 804 PG++G D G +G PG PG PG G PG G+ GHPGP G KG KG++G Sbjct: 1344 PPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEG 1403 Query: 805 PPGKPGPPGPPGIPFNERNGMSSLYKIKG--GV----NVPSYPGPPGPPG---------- 848 P GK G G PG R G+ L + G GV + GP G PG Sbjct: 1404 PKGKQGKAGAPG-----RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458 Query: 849 --PKGDPGPVG------EPGAMGLPGLEGFPGVKGDRG---PAGPPGIAGMSGKPGAPGP 897 GDPGP+G PG GLPG +G PG KG+ G GPPG G G+ G PG Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGN 1518 Query: 898 PGVPGEPGERGPVGDIGFPG------PEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGE 951 G PG G+ G G++GFPG P+GP G G G G G G+MGK G GP G Sbjct: 1519 QGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGI 1578 Query: 952 RGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSP 1003 G G+PG +G +G RG GL G P GPPG + G PG GPPG P Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQG------PRGPPGPR---GRPGPPGPPGGP 1621 Score = 446 bits (1148), Expect = e-125 Identities = 267/663 (40%), Positives = 328/663 (49%), Gaps = 66/663 (9%) Query: 288 IPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE 347 + KG+ G+ G PG PG KG G PG G G PG PG +G G G G G KG +G Sbjct: 1008 VGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGP 1067 Query: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGP------ 401 +G AG G GLKG GP G PG G++G G G G GI GP GP Sbjct: 1068 RGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGL 1127 Query: 402 PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDK 461 PG+ G +G +G GPPG+ GP GPPG G G+ G + G + GL G + Sbjct: 1128 PGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQ--GLIGQR 1185 Query: 462 GETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDP---GPPGLI 518 GE GL G G +GP G KG+ G+P GE G++G+ G++G G G PG GP G Sbjct: 1186 GEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKS 1245 Query: 519 GSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGE 578 G G KG+ G+ G+ G +G G++G+PG+ G PG G KG +G +GP G PG G Sbjct: 1246 GKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGS----LGPTGAPGRMGA 1301 Query: 579 AGPPG-KSLPGEPGLDGNPGAPGPRGPKGERG----LPGVHGSPGDIGPQG-IGIPGRTG 632 G PG G G+ G G PGP+G KGE+G G G PGD GP G G G G Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPG 1361 Query: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692 G G+ G+QG RG PG G PG PG G PG G G GP G Sbjct: 1362 DPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK-------------- 1407 Query: 693 KNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGER 752 +A PG +G +G G PG + R+G G GP G+PGR+G G +GE+ Sbjct: 1408 -----QGKAGAPG---RRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQ 1459 Query: 753 GYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPP 812 G G PG G G +G PG+ G PG GPPG G +G PG G G++G++G G PG Sbjct: 1460 GDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQ 1519 Query: 813 GPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPG 872 G PG G PG G G PG G G G PG GF G Sbjct: 1520 GEPG-----------------------SKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKG 1556 Query: 873 VKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDG 932 ++G RGP G G G+ G G GP G+PG G++G GD G GP GP G G G G Sbjct: 1557 IQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPG 1616 Query: 933 IPG 935 PG Sbjct: 1617 PPG 1619 Score = 385 bits (989), Expect = e-106 Identities = 245/579 (42%), Positives = 290/579 (50%), Gaps = 77/579 (13%) Query: 571 GLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGR 630 G PGPKG+ G LPG PGL G PG PG RGP RG PG +G+PG +PG Sbjct: 625 GPPGPKGDCG-----LPGPPGLPGLPGIPGARGP---RGPPGPYGNPG--------LPGP 668 Query: 631 TGAQGPAGEPGIQGPR---GLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGD 687 GA+G G+PG+ + G G G PG GN G PGR G G PGP G P G Sbjct: 669 PGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGP 728 Query: 688 IGAL-LKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPK 746 G+ K + G + +PG + G +G G G G G RG PG+PG+ + Sbjct: 729 EGSPGAKGYPG--RQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGK---R 783 Query: 747 GSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGL------MGRTGHPGPTGAKGEK 800 G G G+PG+ GE+G GL G PG G PGP G PGL +G G+PGP G KG Sbjct: 784 GKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLM 843 Query: 801 GSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPG 860 GS G PG G G G+P +G KG +P +PG G PGP G G G G Sbjct: 844 GSVGEPGLKGDKGEQGVP--GVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIG 901 Query: 861 AMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA---PGPPGVPGEPGERGPVGDIGFPG 917 G PG EGFPG D GP G G GM GKPGA PGP G G G+ GP+G G PG Sbjct: 902 FPGPPGPEGFPG---DIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPG 958 Query: 918 PEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERG---------DQGIPGDRGSQGERG 968 EG G+ G G+ G+ G +G G PG GP GE+G + GI G++G +G G Sbjct: 959 LEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG 1018 Query: 969 KPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLR 1028 PG+ G KG++G G PG G+ G PG QGPPGS G PG+ Sbjct: 1019 PPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGM-------------------- 1058 Query: 1029 IFEERMAVFLSQLKLPAAMLAAQ-AYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG 1087 R A + P Q + G GPPG G PG PG G G RG G RG PG Sbjct: 1059 ----RGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPG 1114 Query: 1088 IGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 I PG G PGT GLPG PG GPQGP GP G P+ Sbjct: 1115 I--PGPSGPPGTK--GLPGEPGPQGPQGPIGPPGEMGPK 1149 Score = 368 bits (945), Expect = e-101 Identities = 236/561 (42%), Positives = 286/561 (50%), Gaps = 77/561 (13%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 P +Q + + + ++G G+PG G PG KG GEPG G G G PG+ G +G G+ Sbjct: 1095 PGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGA 1154 Query: 336 KGETGEKGEQGEKGD---------PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP--- 383 GE G GE G KGD L G GE GL+GD GP GP G KG++GD GP Sbjct: 1155 VGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGE 1214 Query: 384 ------------PGPPALPGSLGIQGPQGPPGKEGQRGR---------RGKTGPPGKPGP 422 GPP PG G++GP+G GK+G++GR +G+ G G PG Sbjct: 1215 HGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGD 1274 Query: 423 PGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEP 482 PGPPG PG +G +LG G GL G G G+ G G GPKG+KGE Sbjct: 1275 PGPPGTPGPKGSRGSLGPTGAPGRMGAQGEP--GLAGYDGHKGIVGPLGPPGPKGEKGEQ 1332 Query: 483 GEP-FTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLK---GQQGSAGSMGPRGP 538 GE +G G G+ G +G +G +GEPGDPG PG G GL+ GQQG G GPRG Sbjct: 1333 GEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGW 1392 Query: 539 PGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA 598 PG G G G GKQG G G G+ G GLPGP+G G G L G G DG PG Sbjct: 1393 PGPKGSKGAEGPKGKQGKAGAPG-RRGVQGLQGLPGPRGVVGRQG--LEGIAGPDGLPGR 1449 Query: 599 PGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQGPRGLPGL---PGT 654 G G +GE+ G G PG +GP G G PG G G G PG +G GLPG PG Sbjct: 1450 DGQAGQQGEQ---GDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGK 1506 Query: 655 PGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEG 714 GT G G+PG G+PG G PGD G++G PG+ G +G Sbjct: 1507 RGTEGRTGLPGNQGEPGSKGQPGDS------GEMG-------------FPGMAGLFGPKG 1547 Query: 715 GAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPG 774 G+ G KG GPRGPPG+ G+EG G G G G+PG KGD+G +G G+ Sbjct: 1548 PPGDIG------FKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGL-- 1599 Query: 775 APGPTGPPGLMGRTGHPGPTG 795 GP GPPG GR G PGP G Sbjct: 1600 -QGPRGPPGPRGRPGPPGPPG 1619 Score = 343 bits (881), Expect = 4e-94 Identities = 252/684 (36%), Positives = 298/684 (43%), Gaps = 144/684 (21%) Query: 529 SAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPG 588 ++G+ PR P V PG K+ I E G P P P PGK+ Sbjct: 511 TSGTSTPRTAPA-VPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLR----PGKAARD 565 Query: 589 EPGLDGNPGAPGPRGPK-GERGLPGVHGSPGDI----------GPQGIGIPGRT------ 631 P L P PR P+ ++ P + +P G + G T Sbjct: 566 VP-LSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLM 624 Query: 632 GAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPG------DPIALP-- 683 G GP G+ G+ GP GLPGLPG PG G G PG G PGLPGPPG DP P Sbjct: 625 GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684 Query: 684 ----LLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG- 738 GD+G L GN PG K +KG G AG PG+ +G G +G PG Sbjct: 685 AHDGAKGDMG--LPGLSGN--PGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGR 740 Query: 739 --IPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA 796 +PG G G KG RGY G+PG G G G G+PG PG G MG G PG G Sbjct: 741 QGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK---MGMPGFPGVFGE 797 Query: 797 KGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPV 856 +G G DG PG+ G PGPPG+P G+ + G + P G G G G+PG Sbjct: 798 RGPPGLDGNPGELGLPGPPGVP-----GLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852 Query: 857 GEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA------------PGPPGVPGEP 904 G+ G G+PG+ G PG +GD+G G PG G GKPG PGPPG G P Sbjct: 853 GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFP 912 Query: 905 GERGPVGDIG------------FPGP---------EGPSGKPGINGKDGIPGAQGIMGKP 943 G+ GP GD G PGP EGP G PG G +G PG +G G+P Sbjct: 913 GDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRP 972 Query: 944 GDRGPKGERGDQGIPGDRGSQGERG------KPGLTGMKGAIGPMGPPGNKGSMGSPGHQ 997 G G KGE GD G PG G QG G +PG+ G KG G MGPPG G GS GH Sbjct: 973 GLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHP 1032 Query: 998 GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPG 1057 G PG G PG P P ++ G PG Sbjct: 1033 GMPGGMGTPGEPG---------------------------------PQGPPGSR--GPPG 1057 Query: 1058 PPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTS-------ALGLPGSP- 1108 G G GP G GP G +G +G +G PG G PG PG G + + G PG P Sbjct: 1058 MRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPG 1117 Query: 1109 -----------GAPGPQGPPGPSG 1121 G PGPQGP GP G Sbjct: 1118 PSGPPGTKGLPGEPGPQGPQGPIG 1141 Score = 177 bits (448), Expect = 7e-44 Identities = 180/634 (28%), Positives = 225/634 (35%), Gaps = 143/634 (22%) Query: 610 LPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPG--------TPGTPGND 661 LP G G + P P RT P + GP P LP P P + Sbjct: 282 LPAGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASV 341 Query: 662 GVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK 721 G R +P P A I L S+ +KS + A Sbjct: 342 GGSTRTPRPAAAQPSQKITAT----KIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFT 397 Query: 722 YDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGI--PGEKGDEGLQGIPGIPGAPGPT 779 ++ + + P P +P R K + PG+ P L P PT Sbjct: 398 KSALPTQKQVPPTSRP-VPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPT 456 Query: 780 -----------------------GPPGLMGRTGHPGPTGAKGE------------KGSDG 804 PP + P PT G+ Sbjct: 457 LARTEAKITSHASKPASARTSTHKPPPFTALSSSPAPTPGSTRSTRPPATMVPPTSGTST 516 Query: 805 PPGKPGPPGPPGIPFNERNGMSSLYKIKGGVN------VPSYPGP-------------PG 845 P P P P P + + S K G VP PG P Sbjct: 517 PRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPS 576 Query: 846 PPGPK------------------GDPGPVGE-------PGAMGLPGLEGFPGVKGDRGPA 880 P P+ P P G+ P L G PG KGD G Sbjct: 577 PRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAGSTPFPLLMGPPGPKGDCGLP 636 Query: 881 GPPGIAGMSGKPGAPGP---------PGVPGEPGERGPVGDIGF------PGPEGPSGKP 925 GPPG+ G+ G PGA GP PG+PG PG +G GD G G +G G P Sbjct: 637 GPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLP 696 Query: 926 GINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPP 985 G++G G PG +G G P GP G G+QG PG GS G +G PG G+ G +G GP Sbjct: 697 GLSGNPGPPGRKGHKGYP---GPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPK 753 Query: 986 GNKGSMGSPGHQGPPGSP---GIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK 1042 G++G +G PG G PGS G+PG+P + K +F ER Sbjct: 754 GSRGYIGLPGLFGLPGSDGERGLPGVPG------KRGKMGMPGFPGVFGERGP------- 800 Query: 1043 LPAAMLAAQAYGRPGPPGKDGL------PGPPGDPGPQGYRGQKGERGEPGI-GLPGSPG 1095 P G PGPPG GL GP G PGP+G +G G GEPG+ G G G Sbjct: 801 -PGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQG 859 Query: 1096 LPGTSA-------LGLPGSPGAPGPQGPPGPSGR 1122 +PG S G G PG PG +G PGP G+ Sbjct: 860 VPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGK 893 Score = 147 bits (371), Expect = 6e-35 Identities = 126/403 (31%), Positives = 150/403 (37%), Gaps = 96/403 (23%) Query: 772 IPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKI 831 + +P PT PG R+ P T G+ P P P P P + + S Sbjct: 487 LSSSPAPT--PGST-RSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASK 543 Query: 832 KGGVN------VPSYPGPPGPPGPKGD----PGP-VGEPGAMGLPGLEGFPGVKGDRGPA 880 K G VP PG P D P P +P P L P P Sbjct: 544 KAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPR 603 Query: 881 GPPG------IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI---NGKD 931 +AG + P GPPG P GD G PGP G G PGI G Sbjct: 604 PTSSGYSIFHLAGSTPFPLLMGPPG---------PKGDCGLPGPPGLPGLPGIPGARGPR 654 Query: 932 GIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSM 991 G PG G G PG G KG++GD G+ + G +G GL G+ G GP G G+KG Sbjct: 655 GPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYP 714 Query: 992 GSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQ 1051 G GH G G PG G P Sbjct: 715 GPAGHPGEQGQPGPEGSP------------------------------------------ 732 Query: 1052 AYGRPGPPGKDGLPGPPGDPGPQGYRG------------QKGERGEPGI-------GLPG 1092 G G PG+ GLPGP GDPGP+G RG GERG PG+ G+PG Sbjct: 733 --GAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPG 790 Query: 1093 SPGLPGTSAL-GLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSH 1134 PG+ G GL G+PG G GPPG G L P+ + Sbjct: 791 FPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGY 833 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 592 bits (1525), Expect = e-169 Identities = 409/1055 (38%), Positives = 479/1055 (45%), Gaps = 244/1055 (23%) Query: 285 CQCIPNKGEAGLPGA---------------PGSPGQKGHKGEPGENGLHGAPGFPGQKGE 329 CQC P KG G PG PG G+KG KGE G G+ G G G +G Sbjct: 51 CQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGV 110 Query: 330 QGFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL 389 GF G+ G G G+ G +G P G +G NG +GD GP GPPG +G G GP GP Sbjct: 111 SGFPGADGIPGHPGQGGPRGRP---GYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQ 167 Query: 390 ------------------PGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGI 431 PG G+ G QGPPG+ G G+ G G PG+PGPPGPPGP G Sbjct: 168 KGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQ 227 Query: 432 QGIHQTLGGYYNKDNKGN---------------------------DEHEAG-------GL 457 QG ++ LG Y K KG+ D+++ G+ Sbjct: 228 QG-NRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGI 286 Query: 458 KGD--KGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPP 515 +G KGE G+ GFPG G G GE G P KG +G G G G +G KGE GDPGPP Sbjct: 287 RGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPP 346 Query: 516 GLI-------------GSPGLKGQQGSAGSMGPRGPPGDVGLPG--------EHGIPGKQ 554 GL G PG G QG GS G G PG G PG G+PG+ Sbjct: 347 GLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEM 406 Query: 555 GIKGEKGDPG---------------GIIGPPGLPGP-------------KGEAGPPGKSL 586 G KG GDPG G GPPGLPGP KG AG PG L Sbjct: 407 GPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPG--L 464 Query: 587 PGEPG----------------------LDGNPGAPGPRG---------PKGERGLPGVHG 615 PG PG + G PG PGP+G KG+RG PG HG Sbjct: 465 PGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHG 524 Query: 616 SPGDIGPQGIGIPGRTGAQGPAGEPG------IQGPRGLPGLPGTPGTPGNDGVPGRDGK 669 PG G +G+ PG GA GP G G +G RG PG+PG PG G+DG PGRDG Sbjct: 525 LPGFPGLKGV--PGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGL 582 Query: 670 ---PGLPGPPGDPIALPL-----------------LGDIGALLKNFCGNC----QASVPG 705 PGLPGPPGD I P +G G L G A +PG Sbjct: 583 DGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPG 642 Query: 706 LKSNKGEEGGAGEPGKYD-----SMARKGDI----------GPRGPPGIPGREGPKGSKG 750 G G AG PG+ D A GD GP+G PG+PG GP G+KG Sbjct: 643 PPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKG 702 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG 810 RG PG G G G +G+PG G G GPPG +G G G G G GS GP G PG Sbjct: 703 LRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPG 762 Query: 811 PPGPPG---IP---FNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGD------------ 852 P GPPG +P + G + G + PG GPPG +G Sbjct: 763 PDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQ 822 Query: 853 ---PGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGP 909 PGP G+PG G PGL GFPG G GP G PGI G G PG G PG G P GP Sbjct: 823 PGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAP---GP 879 Query: 910 VGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGK 969 VG G G G +G G G G PG +GI G PG G KG+RG G+ G +G G +G+ Sbjct: 880 VGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGR 939 Query: 970 PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAV-SFEEIKKYINQEVLR 1028 PG G KG G G PG KG G PG +G G PG PG P + ++IK E Sbjct: 940 PGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDE--- 996 Query: 1029 IFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI 1088 + L + A G PG PG G+PG PG PG +G KG+ G PGI Sbjct: 997 ----------GPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPG--HIKGVKGDIGVPGI 1044 Query: 1089 -GLPGSPGLPGTSAL-GLPGSPGAPGPQGPPGPSG 1121 GLPG PG+ G + G PG G+ G +G PG +G Sbjct: 1045 PGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAG 1079 Score = 576 bits (1484), Expect = e-164 Identities = 386/1001 (38%), Positives = 463/1001 (46%), Gaps = 211/1001 (21%) Query: 276 PAKQELKDQCQCIPNKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQ-----KGEQ 330 P + K + I KGE G PG PG PG KG G PG +GL G PG PG KG Sbjct: 541 PGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPP 600 Query: 331 GFEGSKGETGEKGEQGEKGDPALA--GLNGENGLKGDLGPHGPP---------------- 372 G G G G KG GE G P L GL G+ G GD G GPP Sbjct: 601 GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQID 660 Query: 373 -----------------------GPKGEKGDTGPPGPP---------------------A 388 GPKG G GPPGP Sbjct: 661 CDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRG 720 Query: 389 LPGSLGIQGPQGPPGKEGQRGRRGKT---GPPGKPGP---PGPPGPPGIQGI-HQTLGGY 441 LPG G +G GPPG G RG +G GP G PGP PGP GPPG +G+ + LG Sbjct: 721 LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ 780 Query: 442 YNKDNKGNDEHEAG--GLKGD------------------KGETGLP---GFPGSVGPKGQ 478 + G GL GD KG+ GLP G PG GP G Sbjct: 781 PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL 840 Query: 479 KGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGP 538 G PG P +G G G PG G G +G+PGD G PG +G GL G +G AG G +G Sbjct: 841 HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGH 900 Query: 539 PGDVGLPGEHGIPGKQGIKGEKGDPG--------GIIGPPGLPGPKGEAG----PPGKSL 586 PG G G G+PG G+KG++G PG G+ G PG PG KGEAG P K L Sbjct: 901 PGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGL 960 Query: 587 PGEPGLDGNPGAPGPRGPKGE--RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQG 644 GEPG G+ G PGP GP G+ + G GD GP +G+ G GA+G G PGI G Sbjct: 961 AGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGP--MGLKGYLGAKGIQGMPGIPG 1018 Query: 645 PRGLPGLPGTP----GTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQ 700 G+PGLPG P G G+ GVPG G PG PG G P G G Sbjct: 1019 LSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPP------GITG----------- 1061 Query: 701 ASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPP-GIPGREGPKGSKGERGYPGIP- 758 PG ++G++G G G Y + GD G G +PGR G KG +G G PG+ Sbjct: 1062 --FPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKG 1119 Query: 759 --GEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHP---GPTGAKGE---------KGSDG 804 GEKG EG G PGI G G GPPGL G+TG P GP G++GE KG DG Sbjct: 1120 FFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDG 1179 Query: 805 PPGKPGPPGPPGIPFNERNGMSSLYKIKG--------GVNVPSYPGPPGPPGPKGDPGPV 856 PG PG PG PG+ G+ L+ + G G ++ PG PGPPG +GDPG Sbjct: 1180 WPGAPGLPGFPGL-----RGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEA 1234 Query: 857 GE-PGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGF 915 PG +G+PG +G G G+RGP G PG+ G PG P + G PG++G G G Sbjct: 1235 NTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGF---PGITPPSNISGAPGDKGAPGIFGL 1291 Query: 916 PGPEGPSGKPGI---------NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGE 966 G GP G PG G G PG G G GD GP+G G G+PG++G +GE Sbjct: 1292 KGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGE 1351 Query: 967 RGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEV 1026 +G G TG GA+G GP G KG G PG G G+PGI GIP Sbjct: 1352 QGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIP----------------- 1394 Query: 1027 LRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEP 1086 +++AV P + G PG PG+ G GPPG+PG +G G+ G +G Sbjct: 1395 -----QKIAV------QPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRG 1443 Query: 1087 GI-GLPGSPGLPG----TSALGLPGSPGAPGPQGPPGPSGR 1122 G+ +PG G G +G G+PG PG G PG GR Sbjct: 1444 GVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGR 1484 Score = 569 bits (1467), Expect = e-162 Identities = 393/979 (40%), Positives = 468/979 (47%), Gaps = 174/979 (17%) Query: 284 QCQCIPN----KGEAGLPGAPG------SPGQKGHKGEPGENGLHGAPGFPGQKGEQGFE 333 +C+C KG GLPG G PG+KG +G+PG++GL G PG G G G Sbjct: 482 ECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAP 541 Query: 334 GSKGETGE------KGEQGEKGDPALAGLNGENG------LKGDLGPHGPPGPKGEKGDT 381 G KG G+ KGE+G+ G P + G+ G++G L G G GPPG G KG Sbjct: 542 GPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-GIKGPP 600 Query: 382 GPPGPPALPGSLGIQGPQGPPGK-----EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQ 436 G PG P +PG+ G G GPPG +GQRG G G PG PG GPPGP G G Q Sbjct: 601 GDPGYPGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPG--Q 658 Query: 437 TLGGYYNKDNKGNDEHEA---GGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGD 493 K G D EA G + G KG GLPG PG G KG +G PG G G Sbjct: 659 IDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGP 718 Query: 494 RGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMG---PRGPPGDVGLPGE--- 547 RG PG G +G G PG GP G G+ GL G GS G +G P GPPG+ GLPGE Sbjct: 719 RGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLG 778 Query: 548 --------HGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKS----LPGEP 590 G+PG+ G+KG GD G G G PG+PG KG+ G PG S L G P Sbjct: 779 AQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPP 838 Query: 591 GLDGNPGAPGPRGP------KGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAG----- 638 GL G PGAPG GP G GLPG G PGD G G +G+ G +G +G AG Sbjct: 839 GLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQ 898 Query: 639 -EPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGAL----LK 693 PG G +G+ G+PGTPG G+ G PG DG G+PG G P G+ G LK Sbjct: 899 GHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLK 958 Query: 694 NFCGNCQASVPGLKSNKGEEGGAGEP-----GKYDSMARKGDIGPRGPPGIPGREGPKGS 748 G PG K ++G+ G G P G D KGD GP G G G +G +G Sbjct: 959 GLAGE-----PGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGM 1013 Query: 749 KGERGYPGIPG----------EKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKG 798 G G GIPG KGD G+ GIPG+PG PG GPPG+ TG PG G++G Sbjct: 1014 PGIPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGI---TGFPGFIGSRG 1070 Query: 799 EKGSDGP----------------------PGKPG---PPGPPGIP----FNERNGMSSLY 829 +KG+ G PG+PG G GIP F G Sbjct: 1071 DKGAPGRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDI 1130 Query: 830 KIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRG-PAGP-----P 883 G V GPPG G G PG G PG+ G G G PG KGD G P P P Sbjct: 1131 GFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFP 1190 Query: 884 GIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPG----INGKDGIPGAQGI 939 G+ G+ G G PG G PG PG GD GFPGP G G PG + G G+PG +G Sbjct: 1191 GLRGIRGLHGLPGTKGFPGSPGS-DIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGD 1249 Query: 940 MGKPGDRGPKGERGDQGIPGDR------GSQGERGKPGLTGMKGAIGPMGPPGNKGSMGS 993 G PG+RGP G G QG PG G+ G++G PG+ G+KG GP GPPG+ GS Sbjct: 1250 QGAPGERGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGS 1309 Query: 994 PGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAY 1053 G G PG+PG PG A + R VF LP Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGP-------------QGRPGVF----GLP--------- 1343 Query: 1054 GRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGL-----PGS 1107 G GP G+ G G G G G RG KG +G+PG G PG+ G PG + + PG+ Sbjct: 1344 GEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGT 1403 Query: 1108 PGAPGPQGPPGPSGRCNPE 1126 G G +GPPG G P+ Sbjct: 1404 VGPQGRRGPPGAPGEMGPQ 1422 Score = 569 bits (1467), Expect = e-162 Identities = 368/921 (39%), Positives = 442/921 (47%), Gaps = 163/921 (17%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGE--------------------NGLHGAP-GFPGQKGEQ 330 G+AGLPG PG G G G PG+ G G P G PG G Sbjct: 636 GDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLPGLPGPP 695 Query: 331 GFEGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALP 390 G G+KG G G G G P GL G+ G +G GP G GP+G KG G PGP P Sbjct: 696 GPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSP 755 Query: 391 GSLGIQGPQGPPGKEG--------QRGRRGKTGPPGKPGP---PGPPGPPGIQGIHQTLG 439 G +G+ GP GPPG+ G Q G RG G PG+PG PG GPPG +G G Sbjct: 756 GPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPG 815 Query: 440 GYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV 499 GLKG G G G PG GP G G PG P +G G G PG Sbjct: 816 --------------MPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGR 861 Query: 500 IGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE 559 G G +G+PGD G PG +G GL G +G AG G +G PG G G G+PG G+KG+ Sbjct: 862 EGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGD 921 Query: 560 KGDPG--------GIIGPPGLPGPKGEAG----PPGKSLPGEPGLDGNPGAPGPRGPKGE 607 +G PG G+ G PG PG KGEAG P K L GEPG G+ G PGP GP Sbjct: 922 RGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPV 981 Query: 608 --RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPG----TPGND 661 G+ + G GD GP +G+ G GA+G G PGI G G+PGLPG PG G+ Sbjct: 982 ILPGMKDIKGEKGDEGP--MGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPGHIKGVKGDI 1039 Query: 662 GVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGK 721 GVPG G PG PG G P G G PG ++G++G G G Sbjct: 1040 GVPGIPGLPGFPGVAGPP------GITG-------------FPGFIGSRGDKGAPGRAGL 1080 Query: 722 YDSMARKGDIGPRGPP-GIPGREGPKGSKGERGYPGIPG---EKGDEGLQGIPGIPGAPG 777 Y + GD G G +PGR G KG +G G PG+ G EKG EG G PGI G G Sbjct: 1081 YGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTG 1140 Query: 778 PTGPPGLMGRTGHPG---PTGAKGE---------KGSDGPPGKPGPPGPPGIPFNERNGM 825 GPPGL G+TG PG P G++GE KG DG PG PG PG PG+ G+ Sbjct: 1141 VQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGL-----RGI 1195 Query: 826 SSLYKIKGGVNVPSYPGP--------PGPPGPKGDPGPVGE-PGAMGLPGLEGFPGVKGD 876 L+ + G P PG PGPPG +GDPG PG +G+PG +G G G+ Sbjct: 1196 RGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGE 1255 Query: 877 RGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI--------- 927 RGP G PG+ G PG P + G PG++G G G G GP G PG Sbjct: 1256 RGPPGSPGLQGF---PGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGD 1312 Query: 928 NGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGN 987 G G PG G G GD GP+G G G+PG++G +GE+G G TG GA+G GP G Sbjct: 1313 TGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGP 1372 Query: 988 KGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAM 1047 KG G PG G G+PGI GIP +++AV P + Sbjct: 1373 KGDPGFPGAPGTVGAPGIAGIP----------------------QKIAV------QPGTV 1404 Query: 1048 LAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIG-LPGSPGLPGT------- 1099 G PG PG+ G GPPG+PG +G G+ G +G G+ +PG G G Sbjct: 1405 GPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPI 1464 Query: 1100 SALGLPGSPGAPGPQGPPGPS 1120 G PG PG+PG G PG S Sbjct: 1465 GQEGAPGRPGSPGLPGMPGRS 1485 Score = 565 bits (1455), Expect = e-160 Identities = 382/919 (41%), Positives = 447/919 (48%), Gaps = 123/919 (13%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENG----------LHGAPGFPGQKGEQGFEGSKGETG 340 KG AG PG PGSPG +G KG G+ G + G PG PG KG G G Sbjct: 456 KGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGING------ 509 Query: 341 EKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDT------GPPGPPALPGSLG 394 E G +G++GDP GL G GLKG G G PGPKG KGD+ G G P +PG G Sbjct: 510 EPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPG 569 Query: 395 IQGPQGPPGKEGQRGRRGKTGPPGK--PGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEH 452 ++G G PG++G G G GPPG GPPG PG PGI G T G G Sbjct: 570 MKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGYPGIPGTKGTPG------EMGPPGL 623 Query: 453 EAGGLKGDKG---ETGLPGFPGSVGPKGQKGEPGE-----PFTKGEKGDRGE---PGVIG 501 GLKG +G + GLPG PG +GP G G PG+ + GDR E PG IG Sbjct: 624 GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIG 683 Query: 502 SQGVKGEPGDPGPPGLIGSPGLKGQQGSAGS---MGPRGPPGDVGLPGEHGIPGKQGIKG 558 G KG PG PGPPG G+ GL+G G AG+ GPRG PGD G G G PG G +G Sbjct: 684 --GPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRG 741 Query: 559 EKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNP--GAPGPRGPKGERGLPGVHGS 616 KG G + GP G PGP G GP G PGE GL G PGPRG G G PG+ G Sbjct: 742 SKGAVG-LPGPDGSPGPIGLPGPDGP--PGERGLPGEVLGAQPGPRGDAGVPGQPGLKGL 798 Query: 617 PGDIGPQGI----------GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGR 666 PGD GP G G+ G+ G GP+G+PG+ GP GL G PG PG G G+PG Sbjct: 799 PGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGI 858 Query: 667 DGKPGLPGPPGDPIALPLLGDIGALLKNFCGNC-------QASVPGLKSNKGEEGGAGEP 719 G+ GLPG GDP G +G +K G+ + PG KG +G G P Sbjct: 859 PGREGLPGDRGDPGDTGAPGPVG--MKGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTP 916 Query: 720 GKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPT 779 G G G +G PG+ GR G GSKGE G+ GIPG KG G G G G PGP Sbjct: 917 GLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPP 976 Query: 780 GPPGLM--------GRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP-FNERNGMSSLYK 830 GPP ++ G G GP G KG G+ G G PG PG GIP R G + Sbjct: 977 GPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRPG--HIKG 1034 Query: 831 IKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPG---------VKGDRGPAG 881 +KG + VP PG PG PG G PG G PG +G G +G PG GD G G Sbjct: 1035 VKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIG 1094 Query: 882 P----PGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQ 937 PG G+ G+ G G PG+ G GE+G GDIGFPG G +G G G G G Sbjct: 1095 DTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFP 1154 Query: 938 GIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQ 997 G+ G PG +G G G G GD G G G PG G++G G G PG KG GSPG Sbjct: 1155 GLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSD 1214 Query: 998 --GPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGR 1055 G PG PG PG D + + +P A G Sbjct: 1215 IHGDPGFPGPPGERGDPGEANTLPGPVG-------------------VPGQKGDQGAPGE 1255 Query: 1056 PGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----GLPGSPGLPGTSAL----GLPGS 1107 GPPG GL G PG P G G++G PGI G G PG PG++AL G G+ Sbjct: 1256 RGPPGSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGN 1315 Query: 1108 PGAPGPQGPPGPSGRCNPE 1126 PGAPG G G +G P+ Sbjct: 1316 PGAPGTPGTKGWAGDSGPQ 1334 Score = 547 bits (1410), Expect = e-155 Identities = 388/989 (39%), Positives = 459/989 (46%), Gaps = 184/989 (18%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFP-------GQKGEQGFEGSKGETGEKG 343 KG GL G G G +G KGE G+ G G P + G +G+ GF G++GE G +G Sbjct: 319 KGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQG 378 Query: 344 EQGEKGDPALAGLN-----------GENGLKGDLGPHGPP----GPKGEKGDTGPPGPPA 388 E G+ G P GL+ GE G KG +G G P GP G G GPPGPP Sbjct: 379 EPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPG 438 Query: 389 LPGSLGIQGPQGPPG-KEGQRGRRGKTGPPGKPGPPGPPGPPGIQG----IHQTLGGYYN 443 LPG P GP G G +G +G+ G PG PG PG GP G +G T G Sbjct: 439 LPG------PPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAI 492 Query: 444 KDNKG----------NDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGE--- 490 K G N E G +GD G+ GLPGFPG G G G PG KG+ Sbjct: 493 KGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRT 552 Query: 491 ---KGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGE 547 KG+RG+PGV G G+KG+ G PG GL G PGL G G G GP G PG G+PG Sbjct: 553 ITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGD-GIKGPPGDPGYPGIPGT 611 Query: 548 HGIPGKQG--------IKGEKGDPG--GIIGPPGLPGPKGEAGPPGK------------- 584 G PG+ G +KG++G PG G+ GPPG GP G AG PG+ Sbjct: 612 KGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGG 671 Query: 585 ---------SLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGI-GIPGRTGAQ 634 + G GL G PG PGP G KG RG+PG G+ G GP+G+ G GR G Sbjct: 672 DRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFP 731 Query: 635 GPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPG-----------LPGP------PG 677 GP G G +G +G GLPG G+PG G+PG DG PG PGP PG Sbjct: 732 GPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQPGPRGDAGVPG 791 Query: 678 DPIALPLLGDIGALLKNFCGNC-QASVPGLKSNKGEEGGAGEPGKYDSMA------RKGD 730 P L GD G F G+ +PGLK G G +G+PG Y G Sbjct: 792 QPGLKGLPGDRGP--PGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQ 849 Query: 731 IGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGL---QGIPGIPGAPGPTGPPGLMGR 787 GP G PGIPGREG G +G+ G G PG G +GL +G G G G G PG G Sbjct: 850 EGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGSPGFKGI 909 Query: 788 TGHPGPTGAKGEKGS---DGPPGKPGPPGPPGIPFNERN-GMSSLYKIKGGVNVPSY--- 840 G PG G KG++GS DG G PG G PG P ++ G + +KG P + Sbjct: 910 DGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIPGLKGLAGEPGFKGS 969 Query: 841 ---PGPPGPP-----------GPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPG-- 884 PGPPGPP G KGD GP+G G +G G++G PG+ G G G PG Sbjct: 970 RGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGLSGIPGLPGRP 1029 Query: 885 --IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGK 942 I G+ G G PG PG+PG PG GP G GFPG G G G G+ G+ G G G Sbjct: 1030 GHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGD 1089 Query: 943 ----------PGDRGPKGERGDQGIPGDRGSQGERGKPG---LTGMKGAIGPMGPPGNKG 989 PG G KGERG GIPG +G GE+G G G+ G G GPPG KG Sbjct: 1090 FGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKG 1149 Query: 990 SMGSPGHQGPPGSPG------IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKL 1043 G PG GPPGS G +PG D + L Sbjct: 1150 QTGFPGLTGPPGSQGELGRIGLPGGKGDDG-----------------------WPGAPGL 1186 Query: 1044 PAAMLAAQAYGRPGPPGKDGLPGPPGDP--GPQGYRGQKGERGEPGIG--LPGSPGLPGT 1099 P G G PG G PG PG G G+ G GERG+PG LPG G+PG Sbjct: 1187 PGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQ 1246 Query: 1100 SA-LGLPGSPGAPGPQGPPGPSGRCNPED 1127 G PG G PG G G G P + Sbjct: 1247 KGDQGAPGERGPPGSPGLQGFPGITPPSN 1275 Score = 540 bits (1392), Expect = e-153 Identities = 382/994 (38%), Positives = 455/994 (45%), Gaps = 202/994 (20%) Query: 291 KGEAGLPGAPGSPG--QKGHKGEPGENGLHGAPGF------PGQKGEQGFEGSKGETGEK 342 KGE G G PG G KG +G G GL G PG PGQKG +G +G +G G + Sbjct: 275 KGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPR 334 Query: 343 GEQGEKGDPALAGL----------NGENGLKGDLGPHGPPGPKGEKGDTGPPGPPAL--- 389 G +GE GDP GL G G G G G PG +GE GD G PGPP L Sbjct: 335 GPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIG 394 Query: 390 --------PGSLGIQGPQGPPGKE----GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQT 437 PG +G +G G PG G G GK GPPG PG PGPPGP G Sbjct: 395 DGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGF------ 448 Query: 438 LGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVG---PKGQKGEPGE-PFTKGEKGD 493 GLKG KG G PG PGS G PKG KG+ GE T+G++ Sbjct: 449 ----------------LFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAI 492 Query: 494 RGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGK 553 +G PG+ G +G G G+PG G G PG Q G G G +G PG++G PG G G Sbjct: 493 KGLPGLPGPKGFAGINGEPGRKGDRGDPG---QHGLPGFPGLKGVPGNIGAPGPKGAKGD 549 Query: 554 QGI---KGEKGDPGGIIGPPGLPGPKGEAGPPGKS-LPGEPGLDGNPG--APGPRGPKGE 607 KGE+G PG PG+PG KG+ G PG+ L G PGL G PG GP G G Sbjct: 550 SRTITTKGERGQPG----VPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGPPGDPGY 605 Query: 608 RGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDG----- 662 G+PG G+PG++GP G+G+PG G +G G+ G+ GP G G PG GTPG Sbjct: 606 PGIPGTKGTPGEMGPPGLGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDV 665 Query: 663 ----------------VPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVP-G 705 + G G PGLPGPPG A L G + F G P G Sbjct: 666 KRAVGGDRQEAIQPGCIGGPKGLPGLPGPPGPTGAKGLRG-----IPGFAGADGGPGPRG 720 Query: 706 LKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGR---EGPKGSKGERGYPGI----- 757 L + G EG G PG KG +G GP G PG GP G GERG PG Sbjct: 721 LPGDAGREGFPGPPGFIGPRGSKGAVGLPGPDGSPGPIGLPGPDGPPGERGLPGEVLGAQ 780 Query: 758 PGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGI 817 PG +GD G+ G PG+ G PG GPPG G G PG G KG+ G GP G+PG GPPG+ Sbjct: 781 PGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGL 840 Query: 818 PFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEG-------- 869 +G +G + +P PG G PG +GDPG G PG +G+ GL G Sbjct: 841 -----HGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFT 895 Query: 870 -------FPGVKGDRGPAGPPGIAGMSGKPGA------PGPPGVPGEPGERGPVGDIGFP 916 PG KG G G PG+ G G PG PG G PG PG +G G G P Sbjct: 896 GEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKGEAGFFGIP 955 Query: 917 GPEGPSGKPGINGKDGIPGAQG-----------IMGKPGDRGPKG------ERGDQGIPG 959 G +G +G+PG G G PG G I G+ GD GP G +G QG+PG Sbjct: 956 GLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPG 1015 Query: 960 D----------------RGSQGERGKPGLTGMKGAIGPMGPPGNKGS---MGSPGHQGPP 1000 +G +G+ G PG+ G+ G G GPPG G +GS G +G P Sbjct: 1016 IPGLSGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAP 1075 Query: 1001 GSPGIPGIPADAVSFEEIKKYINQEVL-RIFEERMAVFLSQLK-------------LPAA 1046 G G+ G F +I IN + ER + LK P Sbjct: 1076 GRAGLYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGI 1135 Query: 1047 MLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQ------KGERGEPGI-GLPGSPGLPGT 1099 G PG G+ G PG G PG QG G+ KG+ G PG GLPG PGL G Sbjct: 1136 TGVTGVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGI 1195 Query: 1100 SAL-------GLPGSPGA-----PGPQGPPGPSG 1121 L G PGSPG+ PG GPPG G Sbjct: 1196 RGLHGLPGTKGFPGSPGSDIHGDPGFPGPPGERG 1229 Score = 503 bits (1296), Expect = e-142 Identities = 355/889 (39%), Positives = 411/889 (46%), Gaps = 162/889 (18%) Query: 333 EGSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGP------PGP 386 +G +G+ G G QG G P L G G G KGD G G PG G KGD G PG Sbjct: 57 KGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGA 116 Query: 387 PALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDN 446 +PG G GP+G PG +G G +G +GP G PG G GPPG QG G Y Sbjct: 117 DGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPK 176 Query: 447 KGNDEH--EAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGS 502 + D + E G GL G +G G PG G +GP G G PG P G KG +G G +G Sbjct: 177 EERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNRG-LGF 235 Query: 503 QGVKGEPGDPGPPGLIGSPG------------------LKGQQGSAGSMGPRGPP--GDV 542 GVKGE GD G PG G P KG++GS G G RG G+ Sbjct: 236 YGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEE 295 Query: 543 GLPGEHGIPGKQGIKGEKGDPG--------GIIGPPGLPGPKGEAGPPG----------- 583 G+ G G+ G G+ GEKG PG G GP G GPKGEAG PG Sbjct: 296 GIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPAYSPHP 355 Query: 584 ---KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGPAGEP 640 K G+PG G G PG +G G+ GLPG G G Q G+PG G +G G+P Sbjct: 356 SLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEMGPKGFIGDP 415 Query: 641 GIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPG-DPIALPLLGDIGALLKNFCGNC 699 GI P L G P PG DG G G PGLPGPPG D L G G F G Sbjct: 416 GI------PALYGGP--PGPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRA--GFPG-- 463 Query: 700 QASVPGLKSNKGEEGGAGEPGKYDS-MARKGDIGPRGPPGIPGREGPKGSKGERGYPGIP 758 PG + KG +G AGE + A KG G GP G G G G KG+RG PG Sbjct: 464 LPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQH 523 Query: 759 GEKGDEGLQGIPGIPGAPGPTGPPG------LMGRTGHPGPTGAKGEKGSDGPPGKPGPP 812 G G GL+G+PG GAPGP G G G G PG G G KG DG PG+ G Sbjct: 524 GLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLD 583 Query: 813 GPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPG 872 G PG+P +G IKG P PG PG PG KG PG +G PG +GLPGL+G G Sbjct: 584 GFPGLPGPPGDG------IKGP---PGDPGYPGIPGTKGTPGEMGPPG-LGLPGLKGQRG 633 Query: 873 VKGDRGPAGPPGIAGMSGKPGAPGP--------PGVPGEPGERGPVGDIGFPGPEGPSGK 924 GD G GPPG G G G PG V G+ E G IG GP G Sbjct: 634 FPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIG-----GPKGL 688 Query: 925 PGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTG---MKGAIGP 981 PG+ G G GA+G+ G PG G G G +G+PGD G +G G PG G KGA+G Sbjct: 689 PGLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGPPGFIGPRGSKGAVGL 748 Query: 982 MGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQL 1041 GP G+ G +G PG GPPG G+PG Sbjct: 749 PGPDGSPGPIGLPGPDGPPGERGLPG---------------------------------- 774 Query: 1042 KLPAAMLAAQA--YGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI----------- 1088 +L AQ G G PG+ GL G PGD GP G+RG +G G PG+ Sbjct: 775 ----EVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSG 830 Query: 1089 --------GLPGSPGLPGTSA-LGLPGSPGA---PGPQGPPGPSGRCNP 1125 GL G PG PG LGLPG PG PG +G PG +G P Sbjct: 831 QPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGP 879 Score = 435 bits (1118), Expect = e-121 Identities = 300/762 (39%), Positives = 351/762 (46%), Gaps = 155/762 (20%) Query: 456 GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPP 515 G +G G GL GFPG G KG KGE G P G KGD G GV G G G PG PG Sbjct: 67 GPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQG 126 Query: 516 GLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGE------------KGDP 563 G G PG G G+ G GP+GPPG G G G G +G KGE +G+P Sbjct: 127 GPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEP 186 Query: 564 G-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLP--GVHGS 616 G G GPPG PG G+ GP G PG G PG PGP+G +G RGL GV G Sbjct: 187 GEPGLVGFQGPPGRPGHVGQMGPVGA-----PGRPGPPGPPGPKGQQGNRGLGFYGVKGE 241 Query: 617 PGDIGPQGI-GIPGRT------------------GAQGPAGEPGI--------QGPRGLP 649 GD+G G GIP T G +G GEPGI +G G P Sbjct: 242 KGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFP 301 Query: 650 GLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSN 709 GL G PG G G PG+ G GL G G G + Sbjct: 302 GLRGYPGLSGEKGSPGQKGSRGLDGYQGPD-------------------------GPRGP 336 Query: 710 KGEEGGAGEPG-----KYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKG-- 762 KGE G G PG + S+A+ G RG PG PG +G GS+GE G PG+PG G Sbjct: 337 KGEAGDPGPPGLPAYSPHPSLAK----GARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLS 392 Query: 763 ---DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPF 819 + +G+PG G G G PG+ G GP G G++G GPPG PGPPGP G F Sbjct: 393 IGDGDQRRGLPGEMGPKGFIGDPGIPALYG--GPPGPDGKRGPPGPPGLPGPPGPDGFLF 450 Query: 820 NERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGE----------------PGAMG 863 + KG P PG PG GPKG G GE PG G Sbjct: 451 GLKGA-------KGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKG 503 Query: 864 LPGLEGFPGVKGDRGPAGP------PGIAGMSGKPGAPGPPGVPGEP------GERGPVG 911 G+ G PG KGDRG G PG+ G+ G GAPGP G G+ GERG G Sbjct: 504 FAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGERGQPG 563 Query: 912 DIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGD--RGPKGERGDQGIPGDRGSQGERGK 969 G PG +G G PG +G DG PG + G PGD +GP G+ G GIPG +G+ GE G Sbjct: 564 VPGVPGMKGDDGSPGRDGLDGFPG---LPGPPGDGIKGPPGDPGYPGIPGTKGTPGEMGP 620 Query: 970 PGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPG-IPADAVSFEEIKKYINQEVLR 1028 PGL G+ G G G PG+ G G PG GPPG G PG I D ++K+ + + Sbjct: 621 PGL-GLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDT----DVKRAVGGD--- 672 Query: 1029 IFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI 1088 + A+ + P + G PGPPG G G G PG G G G RG PG Sbjct: 673 ---RQEAIQPGCIGGPKGLP-----GLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGD 724 Query: 1089 ----GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPE 1126 G PG PG G G G+ G PGP G PGP G P+ Sbjct: 725 AGREGFPGPPGFIGPR--GSKGAVGLPGPDGSPGPIGLPGPD 764 Score = 434 bits (1117), Expect = e-121 Identities = 290/710 (40%), Positives = 332/710 (46%), Gaps = 93/710 (13%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G+AG+PG PG G G +G PG G G PG PG KG+ G G G+ G G G G Sbjct: 784 RGDAGVPGQPGLKGLPGDRGPPGFRGSQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGF 843 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPG------SLGIQGPQGPPGK 404 P G G GL G G G PG +G+ GDTG PGP + G G G QG PG Sbjct: 844 PGAPGQEGPLGLPGIPGREGLPGDRGDPGDTGAPGPVGMKGLSGDRGDAGFTGEQGHPGS 903 Query: 405 EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDKG 462 G +G G G PG G G PG G QG+ G +KG EAG G+ G KG Sbjct: 904 PGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGFPGSKG----EAGFFGIPGLKG 959 Query: 463 ETGLPGFPGSVGPKGQKGEP-----GEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGL 517 G PGF GS G G G P G KGEKGD G G+ G G KG G PG PGL Sbjct: 960 LAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLKGYLGAKGIQGMPGIPGL 1019 Query: 518 IGSPGLKGQQGSA----------------GSMGPRGPPGDVGLPG------EHGIPGKQG 555 G PGL G+ G G G GPPG G PG + G PG+ G Sbjct: 1020 SGIPGLPGRPGHIKGVKGDIGVPGIPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAG 1079 Query: 556 IKGEKG------DPGGIIGPPGLPGPKGEAGPPG----KSLPGEPGLDGNPGAPG----- 600 + GE G D G I PG PG KGE G G K GE G +G+ G PG Sbjct: 1080 LYGEIGATGDFGDIGDTINLPGRPGLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVT 1139 Query: 601 ----PRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGEPGIQG---PRGLPGLP 652 P G KG+ G PG+ G PG G G IG+PG G G G PG+ G RG+ GL Sbjct: 1140 GVQGPPGLKGQTGFPGLTGPPGSQGELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLH 1199 Query: 653 GTPGTPGNDGVPGRD--GKPGLPGPPGD------------PIALP-LLGDIGALLKNFCG 697 G PGT G G PG D G PG PGPPG+ P+ +P GD GA + Sbjct: 1200 GLPGTKGFPGSPGSDIHGDPGFPGPPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPP 1259 Query: 698 NCQA--SVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP 755 PG+ G G+ G KG GP GPPG G KG G G P Sbjct: 1260 GSPGLQGFPGITPPSNISGAPGDKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAP 1319 Query: 756 GIPGEKG---DEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPP 812 G PG KG D G QG PG+ G PG GP G G G+ GPTGA G++G GP G PG P Sbjct: 1320 GTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFP 1379 Query: 813 GPPG-IPFNERNGMSSLYKIKGGVNVPS-YPGPPGPPGPKGDPGPVGEPGAMGLPGLEG- 869 G PG + G+ ++ G P GPPG PG G GP GEPG G PG G Sbjct: 1380 GAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGP 1439 Query: 870 --------FPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVG 911 PG +GD GP G G G G PG PG PG+PG PG +G Sbjct: 1440 QGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIG 1489 Score = 392 bits (1006), Expect = e-108 Identities = 260/650 (40%), Positives = 315/650 (48%), Gaps = 79/650 (12%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 KG +G G G G++GH G PG G+ G PG PG KG++G G G G G +G G Sbjct: 883 KGLSGDRGDAGFTGEQGHPGSPGFKGIDGMPGTPGLKGDRGSPGMDGFQGMPGLKGRPGF 942 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPA--LPGSLGIQGPQGPPGKEGQR 408 P G G G+ G G G PG KG +GD GPPGPP LPG I+G +G G G + Sbjct: 943 PGSKGEAGFFGIPGLKGLAGEPGFKGSRGDPGPPGPPPVILPGMKDIKGEKGDEGPMGLK 1002 Query: 409 GRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETG--- 465 G G G G PG PG G PG+ G G +KG KG+ G Sbjct: 1003 GYLGAKGIQGMPGIPGLSGIPGLPG-------------------RPGHIKGVKGDIGVPG 1043 Query: 466 ---LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD-------PGPP 515 LPGFPG GP G G PG ++G+KG G G+ G G G+ GD PG P Sbjct: 1044 IPGLPGFPGVAGPPGITGFPGFIGSRGDKGAPGRAGLYGEIGATGDFGDIGDTINLPGRP 1103 Query: 516 GLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG--GIIGPPGLP 573 GL G G G G G G +G GD+G PG G+ G QG G KG G G+ GPPG Sbjct: 1104 GLKGERGTTGIPGLKGFFGEKGTEGDIGFPGITGVTGVQGPPGLKGQTGFPGLTGPPGSQ 1163 Query: 574 GPKGEAG-PPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTG 632 G G G P GK G PG G PG PG RG +G GLPG G PG G G PG G Sbjct: 1164 GELGRIGLPGGKGDDGWPGAPGLPGFPGLRGIRGLHGLPGTKGFPGSPGSDIHGDPGFPG 1223 Query: 633 AQGPAGEPG----IQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPG--PPGDPIALPLLG 686 G G+PG + GP G+PG G G PG G PG G G PG PP + P G Sbjct: 1224 PPGERGDPGEANTLPGPVGVPGQKGDQGAPGERGPPGSPGLQGFPGITPPSNISGAP--G 1281 Query: 687 DIGAL----LKNFCGNC----QASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPG 738 D GA LK + G A++PG K + G G G PG + GD GP+G PG Sbjct: 1282 DKGAPGIFGLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPG---TKGWAGDSGPQGRPG 1338 Query: 739 IPGREGPKGSKGERGY------PGIPGEKGDEGLQGIPGIPGAPGPTGPPGL-------- 784 + G G KG +GE+G+ G G++G +G +G PG PGAPG G PG+ Sbjct: 1339 VFGLPGEKGPRGEQGFMGNTGPTGAVGDRGPKGPKGDPGFPGAPGTVGAPGIAGIPQKIA 1398 Query: 785 -----MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNE-RNGMSSLYKIKGGVNVP 838 +G G GP GA GE G GPPG+PG G PG + R G+S++ +G Sbjct: 1399 VQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGDEGPI 1458 Query: 839 SYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVK---GDRGPAGPPGI 885 + GP G G G PG G PG G G+ VK D+ P P G+ Sbjct: 1459 GHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPMCPVGM 1508 Score = 271 bits (693), Expect = 3e-72 Identities = 178/453 (39%), Positives = 219/453 (48%), Gaps = 66/453 (14%) Query: 712 EEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPG 771 E+GG G+PG + +G GP G G PG +G KG KGERG PG+ G KGD G +G+ G Sbjct: 56 EKGGRGQPGP---VGPQGYNGPPGLQGFPGLQGRKGDKGERGAPGVTGPKGDVGARGVSG 112 Query: 772 IPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG------PPGPPGIPFNERNGM 825 PGA G G PG G G PG G G +G GP G PG PPGP G P ++ Sbjct: 113 FPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQGPPGSEGFTGPPGPQG-PKGQKGEP 171 Query: 826 SSLYKIK--------GGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDR 877 +L K + G + + GPPG PG G GPVG PG G PG G G +G+R Sbjct: 172 YALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMGPVGAPGRPGPPGPPGPKGQQGNR 231 Query: 878 GPAGPPGIAGMSGKPGAPGPPGVPGEP------------------GERGPVGDIGFPGP- 918 G G G+ G G G PGP G+P + GE+G G+ G G Sbjct: 232 G-LGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVTFHPDQYKGEKGSEGEPGIRGIS 290 Query: 919 -EGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKG 977 +G G G G G PG G G PG +G +G G QG G RG +GE G PG G+ Sbjct: 291 LKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQGPDGPRGPKGEAGDPGPPGLPA 350 Query: 978 -------AIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIF 1030 A G G PG G+ G PG QG PG PG+PG P ++ + ++ + E+ Sbjct: 351 YSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGPPGLSIGDGDQRRGLPGEM---- 406 Query: 1031 EERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGIGL 1090 F+ +PA G PGP GK G PGPPG PGP G G GL Sbjct: 407 --GPKGFIGDPGIPALY-----GGPPGPDGKRGPPGPPGLPGPPGPDGFL-------FGL 452 Query: 1091 PGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRC 1123 G+ G G GLPGSPGA GP+G G +G C Sbjct: 453 KGAKGRAGFP--GLPGSPGARGPKGWKGDAGEC 483 Score = 243 bits (621), Expect = 6e-64 Identities = 199/646 (30%), Positives = 237/646 (36%), Gaps = 216/646 (33%) Query: 700 QASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPG 759 Q+ + G+K GG G KG G GP G G GP G +G G G G Sbjct: 29 QSVLAGVKKFDVPCGGRDCSGGCQCYPEKGGRGQPGPVGPQGYNGPPGLQGFPGLQGRKG 88 Query: 760 EKGDEGLQGI------------------PGIPGAP---------------------GPTG 780 +KG+ G G+ GIPG P GP G Sbjct: 89 DKGERGAPGVTGPKGDVGARGVSGFPGADGIPGHPGQGGPRGRPGYDGCNGTQGDSGPQG 148 Query: 781 PPGLMGRTGHPGPTGAKGEKGSD------------------------------------- 803 PPG G TG PGP G KG+KG Sbjct: 149 PPGSEGFTGPPGPQGPKGQKGEPYALPKEERDRYRGEPGEPGLVGFQGPPGRPGHVGQMG 208 Query: 804 --GPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPP-------------- 847 G PG+PGPPGPPG + N Y +KG PGP G P Sbjct: 209 PVGAPGRPGPPGPPGPKGQQGNRGLGFYGVKGEKGDVGQPGPNGIPSDTLHPIIAPTGVT 268 Query: 848 ----------GPKGDPG-----PVGEPGAMGLPGLEGFPGVKGDRGP------------A 880 G +G+PG GE G MG PGL G+PG+ G++G Sbjct: 269 FHPDQYKGEKGSEGEPGIRGISLKGEEGIMGFPGLRGYPGLSGEKGSPGQKGSRGLDGYQ 328 Query: 881 GPPGIAGMSGKPGAPGPPGVP----------------------GEPGERGPVGDIGFPGP 918 GP G G G+ G PGPPG+P GEPG +G GD G PGP Sbjct: 329 GPDGPRGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGEPGSQGEPGDPGLPGP 388 Query: 919 EGPS------------------------------GKPGINGKDGIPGAQGIMGKPGD--- 945 G S G PG +GK G PG G+ G PG Sbjct: 389 PGLSIGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGPPGLPGPPGPDGF 448 Query: 946 ----RGPKGERGDQGIPGDRGSQGE-------------------RGKPGLTGMKGAIGPM 982 +G KG G G+PG G++G +G PGL G KG G Sbjct: 449 LFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRCTEGDEAIKGLPGLPGPKGFAGIN 508 Query: 983 GPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLK 1042 G PG KG G PG G PG PG+ G+P + + + + ER Q Sbjct: 509 GEPGRKGDRGDPGQHGLPGFPGLKGVPGNIGAPGPKGAKGDSRTITTKGER-----GQPG 563 Query: 1043 LPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPGI-GLPGSPGLPGTSA 1101 +P G PG G DG PG PG PG G +G G+ G PGI G G+PG G Sbjct: 564 VPGVPGMKGDDGSPGRDGLDGFPGLPGPPG-DGIKGPPGDPGYPGIPGTKGTPGEMGPPG 622 Query: 1102 LGLP------------GSPGAPGPQGPPGPSGRCNPEDCLYPVSHA 1135 LGLP G PG PG GPPGP+G DC V A Sbjct: 623 LGLPGLKGQRGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRA 668 Score = 129 bits (324), Expect = 2e-29 Identities = 76/193 (39%), Positives = 95/193 (49%), Gaps = 31/193 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKG---EQGFEGSKGETG---EKG 343 +KG+ G PGAPG+PG KG G+ G G G G PG+KG EQGF G+ G TG ++G Sbjct: 1309 SKGDTGNPGAPGTPGTKGWAGDSGPQGRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 344 EQGEKGDPALAGLNGENGLKG-------------DLGPHGPPGPKGEKGDTGPPGPPALP 390 +G KGDP G G G G +GP G GP G G+ GP GPP P Sbjct: 1369 PKGPKGDPGFPGAPGTVGAPGIAGIPQKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEP 1428 Query: 391 GSLGIQGPQGPPGK------------EGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTL 438 G G G GP G+ EG G +G G G PG PG PG PG+ G ++ Sbjct: 1429 GFRGAPGKAGPQGRGGVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSI 1488 Query: 439 GGYYNKDNKGNDE 451 G K ++ + E Sbjct: 1489 GYLLVKHSQTDQE 1501 Score = 40.0 bits (92), Expect = 0.013 Identities = 23/66 (34%), Positives = 30/66 (45%) Query: 292 GEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGDP 351 G + +PG G G GH+G G+ G G PG PG G G S G K Q ++ Sbjct: 1444 GVSAVPGFRGDEGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIGYLLVKHSQTDQEPM 1503 Query: 352 ALAGLN 357 G+N Sbjct: 1504 CPVGMN 1509 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 570 bits (1469), Expect = e-162 Identities = 362/906 (39%), Positives = 422/906 (46%), Gaps = 143/906 (15%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKGD 350 +G G PG PG PG KG +G G +GL G PG PG KGE G G G G+ G +G G+ Sbjct: 162 QGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGE 221 Query: 351 PALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGR 410 G G G +G G GP GP G G GPPG P PG G G G G G G Sbjct: 222 RGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGP 281 Query: 411 RGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFP 470 RG+ G PG GP GPPG PG G+ G G A GL G +G G G Sbjct: 282 RGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAG-----APGLPGPRGIPGPVGAA 336 Query: 471 GSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD---------------PGPP 515 G+ G +G GEPG +KGE G++GEPG G QG G G+ PGPP Sbjct: 337 GATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPP 396 Query: 516 GLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP 575 GL GSPG +G G+ G G GPPG G G G+ G G G G+PG ++GP GLPG Sbjct: 397 GLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG-LMGPRGLPGS 455 Query: 576 KGEAGPPGKSLP-GEPGLDGNPGA---------------PGPRGP---------KGERGL 610 G GP GK P G PG+DG PG PGP+GP KG GL Sbjct: 456 PGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGL 515 Query: 611 PGVHGSPGDIGPQGI-------GIPGRTGAQGPAGEPGIQG------PRGLPGLPGTPGT 657 G G+PG G G G+ G G QGP G PG QG P G G PG G Sbjct: 516 AGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGL 575 Query: 658 PGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAG 717 G G+PG G G GPPG+ A G IG+ G G +G G Sbjct: 576 HGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSR-------------GPSGPPGPDGNKG 622 Query: 718 EPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGD---EGLQGIPGIPG 774 EPG ++ G GP G PG G G G KGE+G PG+ GE G+ +G +G PG G Sbjct: 623 EPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVG 682 Query: 775 APGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGI---------PFNERNGM 825 APGP G G G G GP G G +GS G G+ GP GP G P + Sbjct: 683 APGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERG 742 Query: 826 SSLYKIKGGVNVPSYP-GPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPG 884 + K + GV P+ P G GP GP G PGP G G G PG+ GFPG G GP GP G Sbjct: 743 AKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSG 802 Query: 885 IAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPG 944 I+G G PG G G+ G G++GPVG G G GP PG G+ G G G G PG Sbjct: 803 ISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGP---PGFAGEKGPSGEAGTAGPPG 859 Query: 945 DRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPG 1004 GP+G G GI G GS+GERG PG+ G G GP+G G PG +GPPG+ G Sbjct: 860 TPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLG------IAGPPGARGPPGAVG 913 Query: 1005 IPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGL 1064 PG+ G PG G+DG Sbjct: 914 SPGVN--------------------------------------------GAPGEAGRDGN 929 Query: 1065 PGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPG----TSALGLPGSPGAPGPQGPPGP 1119 PG G PG G G KGERG PG IG G+ G PG G G+ G GP GP GP Sbjct: 930 PGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGP 989 Query: 1120 SGRCNP 1125 +G P Sbjct: 990 AGAVGP 995 Score = 555 bits (1430), Expect = e-158 Identities = 359/908 (39%), Positives = 423/908 (46%), Gaps = 125/908 (13%) Query: 288 IPNKGEAGLPGAPGSPGQ------------KGHKGEPGENGLHGAPGFPGQKGEQGFEGS 335 I + G G PGAPG G+ G +GE G GL G G PG G G G+ Sbjct: 249 IGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGA 308 Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPH---GPPGPKGEKGDTGPPGPPALPGS 392 KG G G G G P G+ G G G G G PGP G KG++G G PGS Sbjct: 309 KGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGE---PGS 365 Query: 393 LGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGN-DE 451 G QGP GP G+EG+RG G+ G G PGPPG G PG +G+ G G+ Sbjct: 366 AGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGA 425 Query: 452 HEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGV------IGSQGV 505 G++G G+ G PG PG +GP+G G PG G++G G PG+ IG G Sbjct: 426 SGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGA 485 Query: 506 KGEPGD---PGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGD 562 +GEPG+ PGP G G PG G +G AG G RG PG G G G PG QG++G KG+ Sbjct: 486 RGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGE 545 Query: 563 PGGIIGPP---GLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGD 619 G GPP GLPGP G AG GK PGE GL G G PGP GP+GERG PG G+ G Sbjct: 546 QGP-PGPPGFQGLPGPSGPAGEVGK--PGERGLHGEFGLPGPAGPRGERGPPGESGAAGP 602 Query: 620 IGPQGI----------------GIPGRTGAQGPAGEPGIQGPRGLPGLP------GTPGT 657 GP G G+ G G GP+G G+ G RG G+P G PG Sbjct: 603 TGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL 662 Query: 658 PGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAG 717 G G PGRDG G PG G P GD G +A G G G G Sbjct: 663 RGEIGNPGRDGARGAPGAVGAPGPAGATGDRG----------EAGAAGPAGPAGPRGSPG 712 Query: 718 EPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPG 777 E G+ G GP G G PG +G +G+KG +G G+ G G G G G G PG Sbjct: 713 ERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772 Query: 778 PT------GPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGI--PFNERNGMSSLY 829 P GPPG+ G G G TG G G GPPG PGP G G+ P ++ + Sbjct: 773 PAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG 832 Query: 830 KIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGL---PGLEGFPGVKGDR------GPA 880 ++ G V P + G GP G G GP G PG GL PG+ G PG +G+R G Sbjct: 833 EV-GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAV 891 Query: 881 GPPGIAGMSGKPGAPGP------PGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIP 934 G PG G++G PGA GP PGV G PGE G G+ G GP G G+PG G+ G P Sbjct: 892 GEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951 Query: 935 GAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSP 994 G G +G G GP G G G G+RG G G G G G GP GP G +G G P Sbjct: 952 GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011 Query: 995 GHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYG 1054 G +GP G PG+ G L A +G Sbjct: 1012 GEKGPRGLPGLKG--------------------------------HNGLQGLPGIAGHHG 1039 Query: 1055 RPGPPGKDGLPGPPGDPGPQGYRGQKGERGEPG-IGLPGSPGLPGTSALGLPGSPGAPGP 1113 G PG G GP G GP G G+ G G PG +G G G G G G PG PGP Sbjct: 1040 DQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQ--GPAGPPGPPGP 1097 Query: 1114 QGPPGPSG 1121 GPPG SG Sbjct: 1098 PGPPGVSG 1105 Score = 553 bits (1424), Expect = e-157 Identities = 365/932 (39%), Positives = 425/932 (45%), Gaps = 141/932 (15%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPG----------------QKGEQGFE 333 ++G G G PG PG+ G G G G G PG PG G G Sbjct: 37 DRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLM 96 Query: 334 GSKGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSL 393 G +G G G G +G AG GE G G G GP GP G+ G+ G PG P PG Sbjct: 97 GPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGER 156 Query: 394 GIQGPQGP---------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG----- 439 G+ GPQG PG +G RG G G G+PG PG G PG G + T G Sbjct: 157 GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGAR 216 Query: 440 GYYNKDNKGNDEHEAG-----------GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTK 488 G + + AG G G G G PGFPG+ GPKG+ G G Sbjct: 217 GLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276 Query: 489 GEKGDRGEPGVIGSQGVKGEPGDPGP------------PGLIGSPGLKGQQGSAGSMGPR 536 G G RGE G+ G G G PG+PG PG+ G+PGL G +G G +G Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336 Query: 537 GPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNP 596 G G GL GE G G +G G KG+PG GP G PGP GE G G + GE G G P Sbjct: 337 GATGARGLVGEPGPAGSKGESGNKGEPGS-AGPQGPPGPSGEEGKRGPN--GEAGSAGPP 393 Query: 597 GAPGPRGPKGERGLPGVHGSPGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLP 649 G PG RG G RGLPG G G +GP G G+ G G G GEPG+ GPRGLP Sbjct: 394 GPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLP 453 Query: 650 GLPGTPGTPGND---GVPGRDGKPGLPGPP---GDPIALPLLGDIGAL-------LKNFC 696 G PG G G + G+PG DG+PG GP G+P + G G K Sbjct: 454 GSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHA 513 Query: 697 GNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYP- 755 G A G G G G PG KG+ GP GPPG G GP G GE G P Sbjct: 514 G--LAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571 Query: 756 --------GIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPG 807 G+PG G G +G PG GA GPTGP G G +G PGP G KGE G G G Sbjct: 572 ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631 Query: 808 KPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGL 867 GP GP G+P +G +P G G PG +G+ G G GA G PG Sbjct: 632 TAGPSGPSGLPGE-----------RGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGA 680 Query: 868 EGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGI 927 G P G G G G AG +G G GP G PGE GE GP G GF GP G +G+PG Sbjct: 681 VGAP---GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGA 737 Query: 928 NGKDGIPGAQ---GIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP 984 G+ G G + G++G G G G G G PG GS+G+ G PG+TG GA G GP Sbjct: 738 KGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGP 797 Query: 985 PGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLP 1044 PG G G PG GP G G+ G D V R E Sbjct: 798 PGPSGISGPPGPPGPAGKEGLRGPRGD-----------QGPVGRTGE------------V 834 Query: 1045 AAMLAAQAYGRPGPPGKDGLPGPPGDPGPQ---------GYRGQKGERGEPG----IGLP 1091 A+ G GP G+ G GPPG PGPQ G G +GERG PG +G P Sbjct: 835 GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEP 894 Query: 1092 GSPGLPG-TSALGLPGSPGAPGPQGPPGPSGR 1122 G G+ G A G PG+ G+PG G PG +GR Sbjct: 895 GPLGIAGPPGARGPPGAVGSPGVNGAPGEAGR 926 Score = 550 bits (1418), Expect = e-156 Identities = 365/939 (38%), Positives = 425/939 (45%), Gaps = 113/939 (12%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQ-------------KGEQGFEGSKG 337 +GE G PG PG G+ G G PG G G PG G G G G +G Sbjct: 41 RGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRG 100 Query: 338 ETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQG 397 G G G +G AG GE G G G GP GP G+ G+ G PG P PG G+ G Sbjct: 101 PPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVG 160 Query: 398 PQGP---------PGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG-----GYYN 443 PQG PG +G RG G G G+PG PG G PG G + T G G Sbjct: 161 PQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPG 220 Query: 444 KDNKGNDEHEAG-----------GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKG 492 + + AG G G G G PGFPG+ GPKG+ G G G G Sbjct: 221 ERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAG 280 Query: 493 DRGEPGVIGSQGVKGEPGDPGP------------PGLIGSPGLKGQQGSAGSMGPRGPPG 540 RGE G+ G G G PG+PG PG+ G+PGL G +G G +G G G Sbjct: 281 PRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATG 340 Query: 541 DVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPG 600 GL GE G G +G G KG+PG GP G PGP GE G G + GE G G PG PG Sbjct: 341 ARGLVGEPGPAGSKGESGNKGEPGSA-GPQGPPGPSGEEGKRGPN--GEAGSAGPPGPPG 397 Query: 601 PRGPKGERGLPGVHGSPGDIGPQG-------IGIPGRTGAQGPAGEPGIQGPRGLPGLPG 653 RG G RGLPG G G +GP G G+ G G G GEPG+ GPRGLPG PG Sbjct: 398 LRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPG 457 Query: 654 TPGTPGNDG---VPGRDGKPGLPGPPG---DPIALPLLGDIGALL-------KNFCGNCQ 700 G G +G +PG DG+PG GP G +P + G G K G Sbjct: 458 NIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAG--L 515 Query: 701 ASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPG---- 756 A G G G G PG KG+ GP GPPG G GP G GE G PG Sbjct: 516 AGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGL 575 Query: 757 -----IPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGP 811 +PG G G +G PG GA GPTGP G G +G PGP G KGE G G G GP Sbjct: 576 HGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP 635 Query: 812 PGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFP 871 GP G+P +G +P G G PG +G+ G G GA G PG G P Sbjct: 636 SGPSGLPGE-----------RGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAP 684 Query: 872 GVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKD 931 G G G G AG +G G GP G PGE GE GP G GF GP G +G+PG G+ Sbjct: 685 GPAGATGDRGE---AGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741 Query: 932 GIPGAQG---IMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNK 988 G G +G ++G G G G G G PG GS+G+ G PG+TG GA G GPPG Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPS 801 Query: 989 GSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAML 1048 G G PG GP G G+ G D + E+ + P Sbjct: 802 GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP 861 Query: 1049 AAQAY-------GRPGPPGKDGLPGPPG---DPGPQGYRGQKGERGEPG-IGLPGSPGLP 1097 Q G PG G+ GLPG G +PGP G G G RG PG +G PG G P Sbjct: 862 GPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAP 921 Query: 1098 GTSAL-GLPGSPGAPGPQGPPGPSGRCNPEDCLYPVSHA 1135 G + G PG+ G PG G PG G + PV A Sbjct: 922 GEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAA 960 Score = 540 bits (1390), Expect = e-153 Identities = 357/849 (42%), Positives = 416/849 (48%), Gaps = 92/849 (10%) Query: 336 KGETGEKGEQGEKGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPP----GPPALPG 391 KG G++G +GE+G P G +GE+G G GP GPPGP G G+ G PG Sbjct: 32 KGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91 Query: 392 SLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLG-----GYYNKDN 446 +G+ GP+GPPG G G +G GP G+PG PG GP G +G G G+ K Sbjct: 92 PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPG 151 Query: 447 KGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG 504 + + G G +G G GLPGF G G G G G+P G KG+ G PG G+ G Sbjct: 152 RPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPG 211 Query: 505 VKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPG 564 G G PG G +G+PG G +GS GS+GP GP G +G G G PG G KGE G G Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVG 271 Query: 565 GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG 624 GP G GP+GE G PG L G G GNPGA G G KG GLPGV G+PG GP+G Sbjct: 272 NA-GPAGPAGPRGEVGLPG--LSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRG 328 Query: 625 I----GIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGD-- 678 I G G TGA+G GEPG G +G G G PG+ G G PG G+ G GP G+ Sbjct: 329 IPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG 388 Query: 679 ----PIALPLLGDIGALLKNFCG-NCQASVPGLKSNKGEEGGAGEPGKYDSMARKGD--- 730 P L G G+ + G + +A V G ++G G AG G R G+ Sbjct: 389 SAGPPGPPGLRGSPGS--RGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 731 IGPRGPPGIPGREGPKGSKGERGYPGI---PGEKGDEGLQGIPG---IPGAPGPTGPPGL 784 +GPRG PG PG GP G +G G PGI PG G G +G PG PG GPTG PG Sbjct: 447 MGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGK 506 Query: 785 MGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPP 844 G GH G GA+G G DG G GPPGP G+ +GG PGPP Sbjct: 507 NGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGV--------------QGGKGEQGPPGPP 552 Query: 845 G---PPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGA------P 895 G PGP G G VG+PG GL G G PG G RG GPPG +G +G G Sbjct: 553 GFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPS 612 Query: 896 GPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGP---KGER 952 GPPG G GE G VG +G GP GPSG PG G GIPG +G G+PG RG G Sbjct: 613 GPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRD 672 Query: 953 GDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADA 1012 G +G PG G+ G G G G GA GP GP G +GS G G GP G G G PA A Sbjct: 673 GARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAG-PAGA 731 Query: 1013 VSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPG 1072 K ER A K P G GP G G GP G G Sbjct: 732 AGQPGAKG-----------ERGA------KGPKG-----ENGVVGPTGPVGAAGPAGPNG 769 Query: 1073 PQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNPEDCLYP 1131 P G G +G+ G PG+ G PG+ G G G G G PGP GP G G P P Sbjct: 770 PPGPAGSRGDGGPPGMTGFPGAAGRTGPP--GPSGISGPPGPPGPAGKEGLRGPRGDQGP 827 Query: 1132 VSHAHQRTG 1140 V RTG Sbjct: 828 VG----RTG 832 Score = 536 bits (1381), Expect = e-152 Identities = 347/852 (40%), Positives = 403/852 (47%), Gaps = 101/852 (11%) Query: 291 KGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGE--- 347 KG AGLPG G+PG G +G PG G GA G G GE G GSKGE+G KGE G Sbjct: 309 KGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGP 368 Query: 348 KGDPALAGLNGENGLKGDLGPHGPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQ 407 +G P +G G+ G G+ G GPPGP G +G G G P G G+ GP G G G Sbjct: 369 QGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGP 428 Query: 408 RGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETGLP 467 G RG G G+PG PG GP G+ G +G G +G G G+ Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIG--------------PAGKEGPVGLPGID 474 Query: 468 GFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQG------VKGEPGDPGPPGLIGSP 521 G PG +GP G +GEPG G KG G+PG G +G +G PG G G G P Sbjct: 475 GRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP 534 Query: 522 GLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGP 581 G +G QG G GP GPPG GLPG G G+ G GE+G G G PG GP+GE GP Sbjct: 535 GPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEF-GLPGPAGPRGERGP 593 Query: 582 PGKS-LPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGE 639 PG+S G G G+ G GP GP G +G PGV G+ G GP G G+PG GA AG Sbjct: 594 PGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGA---AGI 650 Query: 640 PGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP-----------------PGDPIAL 682 PG +G +G PGL G G PG DG G G G PGP P P Sbjct: 651 PGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGS 710 Query: 683 P-LLGDIGALLKN-FCGNCQAS-VPGLKSNKGEEGGAGEPGKYDS---MARKGDIGPRGP 736 P G++G N F G A+ PG K +G +G GE G + G GP GP Sbjct: 711 PGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGP 770 Query: 737 PGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGA 796 PG G G G G G+PG G G G GI G PG PGP G GL G G GP G Sbjct: 771 PGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGR 830 Query: 797 KGEKGSDGPPG---------KPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGP---P 844 GE G+ GPPG + G GPPG P G L G + +P G P Sbjct: 831 TGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP-----GPQGLLGAPGILGLPGSRGERGLP 885 Query: 845 GPPGPKGDPGPVG---EPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVP 901 G G G+PGP+G PGA G PG G PGV G G AG G G G PG G PG Sbjct: 886 GVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHK 945 Query: 902 GE---PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIP 958 GE PG GPVG G PGP GP G G +G G G G +G G GP+G G QGI Sbjct: 946 GERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIR 1005 Query: 959 GDRGSQGERGKPGLTGMKGAIGPMGPPG---NKGSMGSPGHQGPPGSPGIPGIPADAVSF 1015 GD+G GE+G GL G+KG G G PG + G G+PG GP G G P P+ Sbjct: 1006 GDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRG-PAGPSGPAGK 1064 Query: 1016 EEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQG 1075 + + P + A G G G G PGPPG PGP G Sbjct: 1065 D----------------------GRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPG 1102 Query: 1076 YRGQKGERGEPG 1087 G + G G Sbjct: 1103 VSGGGYDFGYDG 1114 Score = 494 bits (1271), Expect = e-139 Identities = 316/810 (39%), Positives = 378/810 (46%), Gaps = 100/810 (12%) Query: 370 GPPGPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPP 429 GP G +G +G+ GPPGPP GR G+ GP G PGPPGPPGPP Sbjct: 33 GPAGDRGPRGERGPPGPP---------------------GRDGEDGPTGPPGPPGPPGPP 71 Query: 430 GIQGIHQTLGGYYNKDNKGNDEHEAG--GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFT 487 G+ G Y+ G G G +G G G PG G GP G+ GEPG+ Sbjct: 72 GLGG---NFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGP 128 Query: 488 KGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGE 547 G +G G PG G G G+PG PG G++G G +G G+ G G +G G GL G Sbjct: 129 AGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGL 188 Query: 548 HGIPGKQGIKGEKGDPG-----GIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPR 602 G PG G+KGE G PG G G GLPG +G G PG + G G DG+ G GP Sbjct: 189 KGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPA--GARGSDGSVGPVGPA 246 Query: 603 GPKGERGLPGVHGSPGDIGPQG-IGIPGRTGAQGPAGE---PGIQGPRGLPGLPGT---P 655 GP G G PG G+PG G G +G G G GP GE PG+ GP G PG PG Sbjct: 247 GPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLT 306 Query: 656 GTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGG 715 G G G+PG G PGLPGP G P + G GA + G PG +KGE G Sbjct: 307 GAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGA--RGLVGE-----PGPAGSKGESGN 359 Query: 716 AGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGA 775 GEPG G GP GP G G+ GP G G G PG PG +G G +G+PG G Sbjct: 360 KGEPGS------AGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413 Query: 776 PGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPFN----ERNGMSSLYKI 831 G GPPG G +G G G G+ G G PG GP G PG P N + G L I Sbjct: 414 AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGI 473 Query: 832 KG---------GVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGD---RGP 879 G P G PGP GP GDPG G+ G GL G G PG G+ +GP Sbjct: 474 DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGP 533 Query: 880 AGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 GP G+ G G+ G PGPPG G PG GP G++G PG G G+ G+ G G G +G Sbjct: 534 PGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP 593 Query: 940 MGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGP---PGNKGSMGSPGH 996 G+ G GP G G +G G G G +G+PG+ G G GP GP PG +G+ G PG Sbjct: 594 PGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGG 653 Query: 997 QGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRP 1056 +G G PG+ G + ++ R P A+ A G Sbjct: 654 KGEKGEPGLRGEIGNP----------GRDGAR-------------GAPGAVGAPGPAGAT 690 Query: 1057 GPPGKDGLPGPPGDPGPQGYRGQKGERGEPG----IGLPGSPGLPGTSA-LGLPGSPGAP 1111 G G+ G GP G GP+G G++GE G G G G+ G PG G G G Sbjct: 691 GDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGEN 750 Query: 1112 GPQGPPGPSGRCNPEDCLYPVSHAHQRTGG 1141 G GP GP G P P A R G Sbjct: 751 GVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780 Score = 450 bits (1157), Expect = e-126 Identities = 297/711 (41%), Positives = 346/711 (48%), Gaps = 96/711 (13%) Query: 463 ETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPPGLIGS-- 520 ET G G GP+G++G PG P GE G G PG PG PGPPGL G+ Sbjct: 28 ETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPG---------PPGPPGPPGLGGNFA 78 Query: 521 -----PGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP 575 G+ G G MGPRGPPG G PG G QG GE G+PG GP G GP Sbjct: 79 AQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGF---QGPAGEPGEPGQT-GPAGARGP 134 Query: 576 KGEAGPPGKSLPGEPGLDGNPGAPGPRG---PKGERGLPGVHGSPGDIGPQGIGIPGRTG 632 AGPPGK+ GE G G PG PG RG P+G RG PG G PG G +G G G Sbjct: 135 ---AGPPGKA--GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHN--GLDG 187 Query: 633 AQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALL 692 +G G PG++G G PG GTPG G G+PG G+ G PGP G + +G +G Sbjct: 188 LKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPA- 246 Query: 693 KNFCGNC-QASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKGE 751 G+ PG KGE G G G G GPRG G+PG GP G G Sbjct: 247 -GPIGSAGPPGFPGAPGPKGEIGAVGNAGP------AGPAGPRGEVGLPGLSGPVGPPGN 299 Query: 752 RGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTG---------HPGPTGAKGEKGS 802 G G+ G KG GL G+ G PG PGP G PG +G G PGP G+KGE G+ Sbjct: 300 PGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGN 359 Query: 803 DGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAM 862 G PG GP GPPG P E +G GPPGPPG +G PG G PGA Sbjct: 360 KGEPGSAGPQGPPG-PSGEEGK-------RGPNGEAGSAGPPGPPGLRGSPGSRGLPGAD 411 Query: 863 GLPGLEGFPGVKGDRGPA---GPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE 919 G G+ G PG +G GPA GP G AG G+PG GP G+PG PG GP G E Sbjct: 412 GRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPA------GKE 465 Query: 920 GPSGKPGINGKDGIPGAQGIMGKPGD---RGPKGERGDQGIPGDRGSQGERGKPGLTGMK 976 GP G PGI+G+ G G G G+PG+ GPKG GD G GD+G G G G G Sbjct: 466 GPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPD 525 Query: 977 GAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIF------ 1030 G G GPPG +G G G QGPPG PG G+P + E+ K + + F Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585 Query: 1031 ---EERMAVFLSQLKLPAAMLAAQA-YGRPGPPGKDGLPGP---------------PGDP 1071 ER S P + ++ G PGP G G PG PG+ Sbjct: 586 GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGER 645 Query: 1072 GPQGYRGQKGERGEPGI-GLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSG 1121 G G G KGE+GEPG+ G G+PG G A G PG+ GAPGP G G G Sbjct: 646 GAAGIPGGKGEKGEPGLRGEIGNPGRDG--ARGAPGAVGAPGPAGATGDRG 694 Score = 354 bits (909), Expect = 2e-97 Identities = 221/549 (40%), Positives = 256/549 (46%), Gaps = 88/549 (16%) Query: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFE---GSKGETGEKGEQG 346 NKGE G+ GA G+ G G G PGE G G PG G+KGE G G+ G G +G G Sbjct: 620 NKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPG 679 Query: 347 EKGDPALAGLNGENGLKGDLGPHGPPGPK---GEKGDTGPPGPPALPGSLGIQGPQGPPG 403 G P AG G+ G G GP GP GP+ GE+G+ GP GP G G G G G Sbjct: 680 AVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKG 739 Query: 404 KEGQRGRRGK------TGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGL 457 + G +G +G+ TGP G GP GP GPPG G Sbjct: 740 ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG-----------------------PAGS 776 Query: 458 KGDKGETGLPGFPGSV------GPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGD 511 +GD G G+ GFPG+ GP G G PG P G++G RG G G G GE G Sbjct: 777 RGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGA 836 Query: 512 PGPPGLIGSPGLKGQQGSAGSMGPRGP------PGDVGLPGEHGIPGKQGIKGEKGDPG- 564 GPPG G G G+ G+AG G GP PG +GLPG G G G+ G G+PG Sbjct: 837 VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGP 896 Query: 565 -GIIGPPGLPGPKGEAGPPG-KSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGP 622 GI GPPG GP G G PG PGE G DGNPG GP G G+ G G G PG+IGP Sbjct: 897 LGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGP 956 Query: 623 QG-IGIPGRTGAQGPA------GEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGP 675 G G PG G GPA GE G GP G G G G G G+ G G+PG GP Sbjct: 957 VGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGP 1016 Query: 676 PGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRG 735 G +PGLK + G +G G G + G +GP G Sbjct: 1017 RG-------------------------LPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG 1051 Query: 736 PPGIPGREGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTG 795 P G G GP G G G+PG G G G QG G G PGP GPP G PG +G Sbjct: 1052 PRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPP------GPPGVSG 1105 Query: 796 AKGEKGSDG 804 + G DG Sbjct: 1106 GGYDFGYDG 1114 Score = 313 bits (802), Expect = 6e-85 Identities = 214/532 (40%), Positives = 244/532 (45%), Gaps = 98/532 (18%) Query: 631 TGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGA 690 T +GPAG+ +GPRG G PG PG G DG G G PG PGPPG LG Sbjct: 29 TVRKGPAGD---RGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPG-------LG---- 74 Query: 691 LLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGPKGSKG 750 GN A G KG G G G +GPRGPPG G GP+G +G Sbjct: 75 ------GNFAAQYDG----KGVGLGPGPMGL---------MGPRGPPGAAGAPGPQGFQG 115 Query: 751 ERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPG 810 G PG PG+ G G A GP GPPG G GHPG G GE+G GP G G Sbjct: 116 PAGEPGEPGQTGPAG---------ARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARG 166 Query: 811 PPGPPGIP-FNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVG------EPGAMG 863 PG PG+P F G + L +KG P G PG PG G PG G E G +G Sbjct: 167 FPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVG 226 Query: 864 LPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGE---------PGERGPVGDIG 914 PG G G G GP GP G G +G PG PG PG GE G GP G++G Sbjct: 227 APGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVG 286 Query: 915 FPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTG 974 PG GP G PG G +G+ GA+G G PG G G G +GIPG G+ G G GL G Sbjct: 287 LPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVG 346 Query: 975 MKGAIGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERM 1034 G G G GNKG GS G QGPPG G EE K+ N E Sbjct: 347 EPGPAGSKGESGNKGEPGSAGPQGPPGPSG-----------EEGKRGPNGE--------- 386 Query: 1035 AVFLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGD---PGPQGYRGQKGERGEPGI--- 1088 A P + + G PG G+ G+ GPPG GP G RG G+ G PG Sbjct: 387 AGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGL 446 Query: 1089 ----GLPGSPGLPGTSA----LGLPGSPGAPGP------QGPPGPSGRCNPE 1126 GLPGSPG G + +GLPG G PGP +G PG G P+ Sbjct: 447 MGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498 Score = 275 bits (704), Expect = 1e-73 Identities = 188/496 (37%), Positives = 217/496 (43%), Gaps = 99/496 (19%) Query: 699 CQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPGREGP------KGS---- 748 C A+ L+ +G AG+ G +G+ GP GPPG G +GP G Sbjct: 18 CLATCQSLQEETVRKGPAGDRGP------RGERGPPGPPGRDGEDGPTGPPGPPGPPGPP 71 Query: 749 ------------------------KGERGYPGIPGEKGDEGLQGIPGIPGAP-------- 776 G RG PG G G +G QG G PG P Sbjct: 72 GLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA 131 Query: 777 -GPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIP-FNERNGMSSLYKIKGG 834 GP GPPG G GHPG G GE+G GP G G PG PG+P F G + L +KG Sbjct: 132 RGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQ 191 Query: 835 VNVPSYPGPPGPPGPKGDPGPV------GEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGM 888 P G PG PG G PG GE G +G PG G G G GP GP G G Sbjct: 192 PGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS 251 Query: 889 SGKPGAPGPPGVPGE---------PGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGI 939 +G PG PG PG GE G GP G++G PG GP G PG G +G+ GA+G Sbjct: 252 AGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGA 311 Query: 940 MGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMGPPGNKGSMGSPGHQGP 999 G PG G G G +GIPG G+ G G GL G G G G GNKG GS G QGP Sbjct: 312 AGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGP 371 Query: 1000 PGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPP 1059 PG G EE K+ N E A P + + G PG Sbjct: 372 PGPSG-----------EEGKRGPNGE---------AGSAGPPGPPGLRGSPGSRGLPGAD 411 Query: 1060 GKDGLPGPPGD---PGPQGYRGQKGERGEPG-------IGLPGSPGLPGTSA----LGLP 1105 G+ G+ GPPG GP G RG G+ G PG GLPGSPG G + +GLP Sbjct: 412 GRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLP 471 Query: 1106 GSPGAPGPQGPPGPSG 1121 G G PGP GP G G Sbjct: 472 GIDGRPGPIGPAGARG 487 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.143 0.456 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,457,175 Number of Sequences: 37866 Number of extensions: 6753904 Number of successful extensions: 313740 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 423 Number of HSP's successfully gapped in prelim test: 1400 Number of HSP's that attempted gapping in prelim test: 26859 Number of HSP's gapped (non-prelim): 32118 length of query: 1142 length of database: 18,247,518 effective HSP length: 113 effective length of query: 1029 effective length of database: 13,968,660 effective search space: 14373751140 effective search space used: 14373751140 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.