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Search of human proteins with 47157328
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
(222 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 455 e-128
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 390 e-109
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 293 8e-80
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 210 7e-55
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 210 7e-55
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 176 1e-44
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 174 7e-44
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 140 1e-33
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 124 8e-29
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 114 9e-26
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 114 9e-26
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 108 4e-24
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 98 5e-21
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 98 6e-21
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 98 6e-21
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 96 2e-20
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 79 4e-15
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 79 4e-15
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 79 4e-15
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 65 4e-11
gi|27436957 membrane associated guanylate kinase, WW and PDZ dom... 62 3e-10
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 59 3e-09
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 59 3e-09
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 59 3e-09
gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens] 55 5e-08
gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens] 55 6e-08
gi|218505835 membrane-associated guanylate kinase-related 3 iso... 54 1e-07
gi|155969695 membrane-associated guanylate kinase-related 3 iso... 54 1e-07
gi|74272284 membrane associated guanylate kinase, WW and PDZ dom... 54 1e-07
gi|74272282 membrane associated guanylate kinase, WW and PDZ dom... 54 1e-07
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 455 bits (1171), Expect = e-128
Identities = 222/222 (100%), Positives = 222/222 (100%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 181 DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS 222
DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS
Sbjct: 181 DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS 222
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 390 bits (1002), Expect = e-109
Identities = 192/201 (95%), Positives = 194/201 (96%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 181 DPDEEHLKKSREKYVLELQSP 201
DPDEEHLKKS + E +P
Sbjct: 181 DPDEEHLKKSSQVPRTEAPAP 201
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 293 bits (750), Expect = 8e-80
Identities = 153/201 (76%), Positives = 156/201 (77%), Gaps = 34/201 (16%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS
Sbjct: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQK P
Sbjct: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKVQTP----------------------- 97
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
+ QPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ
Sbjct: 98 -----------DKQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 146
Query: 181 DPDEEHLKKSREKYVLELQSP 201
DPDEEHLKKS + E +P
Sbjct: 147 DPDEEHLKKSSQVPRTEAPAP 167
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 210 bits (535), Expect = 7e-55
Identities = 113/221 (51%), Positives = 143/221 (64%), Gaps = 7/221 (3%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA + P+ P + T P P
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRA---SAAPKPEPVPVQKKTQVTNNPGT----VKIPPK 113
Query: 121 APPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
PP + P DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE ++
Sbjct: 114 RPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLK 173
Query: 181 DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQ 221
+ + ++ KK++EK L + SP+YT+LRDWHH+ SA LNVQ
Sbjct: 174 ESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 214
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 210 bits (535), Expect = 7e-55
Identities = 122/239 (51%), Positives = 151/239 (63%), Gaps = 23/239 (9%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA S K P T S + + A
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
Query: 121 APPPADSAPQQNGQ--PLRP-------------LVP---DASKQRLMENTEDWRPRPGTG 162
DS QQNG+ P RP VP DASK+RL+E+TEDWRPR GT
Sbjct: 117 RGSQGDS-KQQNGKIPPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTT 175
Query: 163 QSRSFRILAHLTGTEFMQDPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQ 221
QSRSFRILA +TGTE +++ + ++ KK++EK L + SP+YT+LRDWHH+ SA LNVQ
Sbjct: 176 QSRSFRILAQITGTEHLKESEADNTKKAKEKIPLHVFSPKYTKLRDWHHEVSARALNVQ 234
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 176 bits (446), Expect = 1e-44
Identities = 108/282 (38%), Positives = 148/282 (52%), Gaps = 62/282 (21%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
F PS S T +P A +
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
Query: 181 DPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS 222
DPDEE L++SRE++ E SPR+ +LR+WHH SA +LNV+S
Sbjct: 242 DPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS 283
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 174 bits (440), Expect = 7e-44
Identities = 100/202 (49%), Positives = 125/202 (61%), Gaps = 17/202 (8%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+TH+EAQNKI+ C L++ L RA S K P T S + + A
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRA----SAAPKPEPVPVQKPTVTSVCSETSQELAEGQR 116
Query: 121 APPPADSAPQQNGQPLRPLV------------PDASKQRLMENTEDWRPRPGTGQSRSFR 168
DS QQNG P + +V DASK+RL+E+TEDWRPR GT QSRSFR
Sbjct: 117 RGSQGDS-KQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFR 175
Query: 169 ILAHLTGTEFMQDPDEEHLKKS 190
ILA +TGTE +++ + ++ KK+
Sbjct: 176 ILAQITGTEHLKESEADNTKKA 197
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 140 bits (352), Expect = 1e-33
Identities = 92/251 (36%), Positives = 125/251 (49%), Gaps = 62/251 (24%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
Query: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
F PS S T +P A +
Sbjct: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
Query: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
Query: 181 DPDEEHLKKSR 191
DPDEE L++SR
Sbjct: 242 DPDEEALRRSR 252
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 124 bits (310), Expect = 8e-29
Identities = 72/146 (49%), Positives = 89/146 (60%), Gaps = 19/146 (13%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M ++ V L GPAPWGFRLQGGKDFN+PL+IS L GGKAAQA V +GD VLSIDG NA
Sbjct: 1 MSNYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQG 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQS-------KPQKASAPAADPPRYT 105
+TH+EAQNKI+ C L++ L RA PVQ KP ++PA + T
Sbjct: 61 MTHLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVS--KVT 118
Query: 106 FAPSVSLNKTARPFG--APPPADSAP 129
+++ NK RPFG + P S P
Sbjct: 119 STNNMAYNKAPRPFGSVSSPKVTSIP 144
Score = 72.8 bits (177), Expect = 2e-13
Identities = 37/73 (50%), Positives = 50/73 (68%), Gaps = 12/73 (16%)
Query: 130 QQNGQPLRPLVP------------DASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
QQNG P + +V DASK+RL+E+TEDWRPR GT QSRSFRILA +TGTE
Sbjct: 234 QQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTE 293
Query: 178 FMQDPDEEHLKKS 190
+++ + ++ KK+
Sbjct: 294 HLKESEADNTKKA 306
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 114 bits (284), Expect = 9e-26
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
Query: 119 FGAPPPADSAPQQNGQP-LRP 138
P A ++P G P LRP
Sbjct: 120 PSPSPEARASPGTPGTPELRP 140
Score = 95.9 bits (237), Expect = 2e-20
Identities = 48/105 (45%), Positives = 66/105 (62%), Gaps = 2/105 (1%)
Query: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
Query: 178 FMQDPDEEHLKKSREKYVLELQSPRYTRLRDWHHQRSAHVLNVQS 222
FMQDPDEE L++SRE++ E SPR+ +LR+WHH SA +LNV+S
Sbjct: 286 FMQDPDEEALRRSRERFETERNSPRFAKLRNWHHGLSAQILNVKS 330
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 114 bits (284), Expect = 9e-26
Identities = 63/141 (44%), Positives = 88/141 (62%), Gaps = 7/141 (4%)
Query: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
Query: 63 HIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPP----RYTFAPSVSLNKTARP 118
H+EAQNKI++ LSL L +++ + P +AP P + P++ N +
Sbjct: 62 HLEAQNKIKSASYNLSLTLQKSK--RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVA 119
Query: 119 FGAPPPADSAPQQNGQP-LRP 138
P A ++P G P LRP
Sbjct: 120 PSPSPEARASPGTPGTPELRP 140
Score = 57.8 bits (138), Expect = 7e-09
Identities = 31/73 (42%), Positives = 42/73 (57%), Gaps = 2/73 (2%)
Query: 118 PFGAPPPADSAPQQNGQPLRPLVPDASKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTE 177
P G+ P D A + ++ +K + ++W R QSRSFRILA +TGTE
Sbjct: 228 PGGSLPIKDLAVDSASPVYQAVIKSQNKPE--DEADEWARRSSNLQSRSFRILAQMTGTE 285
Query: 178 FMQDPDEEHLKKS 190
FMQDPDEE L++S
Sbjct: 286 FMQDPDEEALRRS 298
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 108 bits (270), Expect = 4e-24
Identities = 54/135 (40%), Positives = 82/135 (60%), Gaps = 8/135 (5%)
Query: 1 MDSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGS 60
M + ++ L+GP PWGFRL GGKDF PL+ISR+TPG KAA A + +GD + +IDGEN +
Sbjct: 1 MTTQQIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSN 60
Query: 61 LTHIEAQNKIRACGERLSLGLSRAQ--------PVQSKPQKASAPAADPPRYTFAPSVSL 112
+TH+EAQN+I+ C + L+L ++R++ + K A P+ +
Sbjct: 61 MTHLEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAH 120
Query: 113 NKTARPFGAPPPADS 127
N++A PF A P + +
Sbjct: 121 NRSAMPFTASPASST 135
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 98.2 bits (243), Expect = 5e-21
Identities = 56/133 (42%), Positives = 75/133 (56%), Gaps = 8/133 (6%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A + GD +L+IDG S+TH +
Sbjct: 5 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
Query: 66 AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYT-------FAP-SVSLNKTAR 117
AQ++I+A +L L + R + PQ + A P + F P + N+ A+
Sbjct: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQEFKPIGTAHNRRAQ 124
Query: 118 PFGAPPPADSAPQ 130
PF A D Q
Sbjct: 125 PFVAAANIDDKRQ 137
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 97.8 bits (242), Expect = 6e-21
Identities = 58/143 (40%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
Query: 66 AQNKIRACGERLSLGLSRAQ-------PVQSKPQKASAPAADPPRYTFAPSVSLNKTARP 118
AQN+I+ C + L+L +SR + P SK Q A DP +P+ S +
Sbjct: 65 AQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQ-AHRIHIDPEIQDGSPTTSRRPSGTG 123
Query: 119 FGAPPPADSAPQQNGQPLRPLVP 141
G S GQP R VP
Sbjct: 124 TGPEDGRPSLGSPYGQPPRFPVP 146
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 97.8 bits (242), Expect = 6e-21
Identities = 58/143 (40%), Positives = 79/143 (55%), Gaps = 8/143 (5%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V L GP+PWGFRL GG+DF+ PL+ISR+ G KAA A + GD + +I+GE+ +TH+E
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSKAALAALCPGDLIQAINGESTELMTHLE 64
Query: 66 AQNKIRACGERLSLGLSRAQ-------PVQSKPQKASAPAADPPRYTFAPSVSLNKTARP 118
AQN+I+ C + L+L +SR + P SK Q A DP +P+ S +
Sbjct: 65 AQNRIKGCHDHLTLSVSRPEGRSWPSAPDDSKAQ-AHRIHIDPEIQDGSPTTSRRPSGTG 123
Query: 119 FGAPPPADSAPQQNGQPLRPLVP 141
G S GQP R VP
Sbjct: 124 TGPEDGRPSLGSPYGQPPRFPVP 146
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 95.9 bits (237), Expect = 2e-20
Identities = 47/96 (48%), Positives = 62/96 (64%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V+L GPAPWGFRL GG DFN PL I+R+TPG KAA A + GD +L+IDG S+TH +
Sbjct: 5 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESMTHAD 64
Query: 66 AQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADP 101
AQ++I+A +L L + R + PQ + A P
Sbjct: 65 AQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHP 100
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 78.6 bits (192), Expect = 4e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
Query: 66 AQNKIRACGERLSLGLSRAQ 85
AQ+KIR L L L R+Q
Sbjct: 65 AQSKIRQSPSPLRLQLDRSQ 84
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 78.6 bits (192), Expect = 4e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
Query: 66 AQNKIRACGERLSLGLSRAQ 85
AQ+KIR L L L R+Q
Sbjct: 65 AQSKIRQSPSPLRLQLDRSQ 84
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 78.6 bits (192), Expect = 4e-15
Identities = 36/80 (45%), Positives = 54/80 (67%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V + GPAPWGFR+ GG+DF+ P+ ++++ GKA A + GD +++I+GE+A + H E
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDADLRPGDIIVAINGESAEGMLHAE 64
Query: 66 AQNKIRACGERLSLGLSRAQ 85
AQ+KIR L L L R+Q
Sbjct: 65 AQSKIRQSPSPLRLQLDRSQ 84
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 65.5 bits (158), Expect = 4e-11
Identities = 42/126 (33%), Positives = 63/126 (50%), Gaps = 4/126 (3%)
Query: 6 VVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLTHIE 65
V L G APWGFRL GG + PL +S++ +A +AG+ D +L+I+G + +L+H
Sbjct: 9 VTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAGLRERDQLLAINGVSCTNLSHAS 68
Query: 66 AQNKIRACGERLSLGLSRAQ---PVQS-KPQKASAPAADPPRYTFAPSVSLNKTARPFGA 121
A + I A G +L L + R PVQS P + + P P + + +P
Sbjct: 69 AMSLIDASGNQLVLTVQRLADEGPVQSPSPHELQVLSPLSPLSPEPPGAPVPQPLQPGSL 128
Query: 122 PPPADS 127
P DS
Sbjct: 129 RSPPDS 134
Score = 28.9 bits (63), Expect = 3.7
Identities = 28/78 (35%), Positives = 33/78 (42%), Gaps = 14/78 (17%)
Query: 87 VQSKPQKASAP---AADPPRYTFAPSVSLNKTARPF----GAPPPADSAPQQNGQPLRPL 139
+QS P+ SAP A PP AP S RPF GAP PA P + RP
Sbjct: 419 LQSPPRAQSAPPEAAVLPPSPLPAPVAS----PRPFQPGGGAPTPA---PSIFNRSARPF 471
Query: 140 VPDASKQRLMENTEDWRP 157
P QR + +RP
Sbjct: 472 TPGLQGQRPTTTSVIFRP 489
>gi|27436957 membrane associated guanylate kinase, WW and PDZ domain
containing 2 [Homo sapiens]
Length = 1455
Score = 62.4 bits (150), Expect = 3e-10
Identities = 47/142 (33%), Positives = 72/142 (50%), Gaps = 9/142 (6%)
Query: 2 DSFKVVLE-GPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAG 59
D F V +E G +GF ++GG+++ + L + RL G A + G + VGD ++ I+GE+
Sbjct: 1144 DYFTVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTR 1203
Query: 60 SLTHIEAQNKIRACGERLSLGLSRAQ---PVQSKPQKASAPAADPPRYTFAPSVSLNKTA 116
+TH A I++ G R+ L L R P +P S+PAA P VSL+
Sbjct: 1204 DMTHARAIELIKSGGRRVRLLLKRGTGQVPEYDEPAPWSSPAAAAPGLP-EVGVSLDDGL 1262
Query: 117 RPFG---APPPADSAPQQNGQP 135
PF PP+D + Q + P
Sbjct: 1263 APFSPSHPAPPSDPSHQISPGP 1284
Score = 30.8 bits (68), Expect = 0.96
Identities = 23/91 (25%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 14 WGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTHIEAQNKIRA 72
+GF + GG + + L + + P G AAQ G + GD ++ I+ TH + ++
Sbjct: 436 FGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQS 495
Query: 73 --CGERLSLGLSRAQPVQSKPQKASAPAADP 101
G+ ++L L R P+ P+ + P
Sbjct: 496 VPIGQSVNLVLCRGYPLPFDPEDPANSMVPP 526
Score = 30.4 bits (67), Expect = 1.3
Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 10/121 (8%)
Query: 14 WGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTHIEAQNKIRA 72
+GFR+ GG + P+ I + G A + G + GD ++ +DG TH + +
Sbjct: 788 FGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHRYVIDLMHH 847
Query: 73 CGERLSLGLSRAQPV----QSKPQKASAPAA-----DPPRYTFAPSVSLNKTARPFGAPP 123
+ L+ + V + P+ +P + PR +A + N A A P
Sbjct: 848 AARNGQVNLTVRRKVLCGGEPCPENGRSPGSVSTHHSSPRSDYATYTNSNHAAPSSNASP 907
Query: 124 P 124
P
Sbjct: 908 P 908
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 58.9 bits (141), Expect = 3e-09
Identities = 29/82 (35%), Positives = 47/82 (57%)
Query: 2 DSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSL 61
D + + G APWGFRLQGGK+ PL ++++ KA+ +G+ GD V+SI+G L
Sbjct: 5 DFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADL 64
Query: 62 THIEAQNKIRACGERLSLGLSR 83
T+ E + + + L + + R
Sbjct: 65 TYPEVIKLMESITDSLQMLIKR 86
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 58.9 bits (141), Expect = 3e-09
Identities = 29/82 (35%), Positives = 47/82 (57%)
Query: 2 DSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSL 61
D + + G APWGFRLQGGK+ PL ++++ KA+ +G+ GD V+SI+G L
Sbjct: 5 DFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADL 64
Query: 62 THIEAQNKIRACGERLSLGLSR 83
T+ E + + + L + + R
Sbjct: 65 TYPEVIKLMESITDSLQMLIKR 86
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 58.9 bits (141), Expect = 3e-09
Identities = 29/82 (35%), Positives = 47/82 (57%)
Query: 2 DSFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSL 61
D + + G APWGFRLQGGK+ PL ++++ KA+ +G+ GD V+SI+G L
Sbjct: 5 DFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASGSGLCEGDEVVSINGNPCADL 64
Query: 62 THIEAQNKIRACGERLSLGLSR 83
T+ E + + + L + + R
Sbjct: 65 TYPEVIKLMESITDSLQMLIKR 86
>gi|153070254 MAGI family member, X-linked isoform b [Homo sapiens]
Length = 262
Score = 55.1 bits (131), Expect = 5e-08
Identities = 40/117 (34%), Positives = 62/117 (52%), Gaps = 13/117 (11%)
Query: 7 VLEGPAPWGFRLQGGKDF--NVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTH 63
++ G A +G L GG+D + PL++ L G A + G + VGD VL I+GE+ LTH
Sbjct: 61 LVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTH 120
Query: 64 IEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPSVSLNKTARPFG 120
+A +IRA G +L L + R P+++ P K PR P ++++ P G
Sbjct: 121 AQAVERIRAGGPQLHLVIRR--PLETHPGK--------PRGVGEPRKGVDRSPDPGG 167
>gi|153070258 MAGI family member, X-linked isoform a [Homo sapiens]
Length = 334
Score = 54.7 bits (130), Expect = 6e-08
Identities = 39/106 (36%), Positives = 57/106 (53%), Gaps = 7/106 (6%)
Query: 7 VLEGPAPWGFRLQGGKDF--NVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTH 63
++ G A +G L GG+D + PL++ L G A + G + VGD VL I+GE+ LTH
Sbjct: 128 LVRGYAGFGLTLGGGRDVAGDTPLAVRGLLKDGPAQRCGRLEVGDLVLHINGESTQGLTH 187
Query: 64 IEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPS 109
+A +IRA G +L L + R P+++ P K PR PS
Sbjct: 188 AQAVERIRAGGPQLHLVIRR--PLETHPGKPR--GVGEPRKGVVPS 229
>gi|218505835 membrane-associated guanylate kinase-related 3 isoform
1 [Homo sapiens]
Length = 1481
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Query: 4 FKVVLE-GPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSL 61
+ V LE GP +GF L+GGK++N+ L I RL G A + G + VGD ++ I+GE +
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGI 1079
Query: 62 THIEAQNKIRACGERLSL 79
TH A I+A G ++ L
Sbjct: 1080 THTRAIELIQAGGNKVLL 1097
Score = 28.9 bits (63), Expect = 3.7
Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 26 VPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRA 84
+P I R+ G A + G + VGD + +++G++ L+H I+ G ++L +
Sbjct: 878 IPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAE 937
Query: 85 QPVQSKPQKASAPAADP 101
+ P ++ P
Sbjct: 938 EEHHGPPSGTNSARQSP 954
>gi|155969695 membrane-associated guanylate kinase-related 3 isoform
2 [Homo sapiens]
Length = 1125
Score = 53.9 bits (128), Expect = 1e-07
Identities = 32/78 (41%), Positives = 47/78 (60%), Gaps = 2/78 (2%)
Query: 4 FKVVLE-GPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSL 61
+ V LE GP +GF L+GGK++N+ L I RL G A + G + VGD ++ I+GE +
Sbjct: 1020 YPVELERGPRGFGFSLRGGKEYNMGLFILRLAEDGPAIKDGRIHVGDQIVEINGEPTQGI 1079
Query: 62 THIEAQNKIRACGERLSL 79
TH A I+A G ++ L
Sbjct: 1080 THTRAIELIQAGGNKVLL 1097
Score = 28.9 bits (63), Expect = 3.7
Identities = 17/77 (22%), Positives = 35/77 (45%), Gaps = 1/77 (1%)
Query: 26 VPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAGSLTHIEAQNKIRACGERLSLGLSRA 84
+P I R+ G A + G + VGD + +++G++ L+H I+ G ++L +
Sbjct: 878 IPHKIGRVIEGSPADRCGKLKVGDHISAVNGQSIVELSHDNIVQLIKDAGVTVTLTVIAE 937
Query: 85 QPVQSKPQKASAPAADP 101
+ P ++ P
Sbjct: 938 EEHHGPPSGTNSARQSP 954
>gi|74272284 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform c [Homo sapiens]
Length = 1462
Score = 53.5 bits (127), Expect = 1e-07
Identities = 36/110 (32%), Positives = 54/110 (49%), Gaps = 10/110 (9%)
Query: 2 DSFKVVLE-GPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAG 59
D + V LE G +GF L+GG+++N+ L + RL G A + G + +GD +L I+GE
Sbjct: 1120 DFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTK 1179
Query: 60 SLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAPAADPPRYTFAPS 109
++ H A I+ G R+ L L R S P DP P+
Sbjct: 1180 NMKHSRAIELIKNGGRRVRLFLKRGD--------GSVPEYDPSSDRHGPA 1221
Score = 29.3 bits (64), Expect = 2.8
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 14 WGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDG 55
+GFR+ GG + P+ I + P G A G + GD ++ +DG
Sbjct: 823 FGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDG 865
>gi|74272282 membrane associated guanylate kinase, WW and PDZ domain
containing 1 isoform a [Homo sapiens]
Length = 1287
Score = 53.5 bits (127), Expect = 1e-07
Identities = 35/98 (35%), Positives = 53/98 (54%), Gaps = 4/98 (4%)
Query: 2 DSFKVVLE-GPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDGENAG 59
D + V LE G +GF L+GG+++N+ L + RL G A + G + +GD +L I+GE
Sbjct: 1148 DFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERCGKMRIGDEILEINGETTK 1207
Query: 60 SLTHIEAQNKIRACGERLSLGLSRAQPVQSKPQKASAP 97
++ H A I+ G R+ L L R S P+ A P
Sbjct: 1208 NMKHSRAIELIKNGGRRVRLFLKRGD--GSVPEYAMIP 1243
Score = 29.3 bits (64), Expect = 2.8
Identities = 15/43 (34%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 14 WGFRLQGGKDFNVPLSISRLTPGGKAAQAG-VAVGDWVLSIDG 55
+GFR+ GG + P+ I + P G A G + GD ++ +DG
Sbjct: 851 FGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDG 893
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,302,966
Number of Sequences: 37866
Number of extensions: 559123
Number of successful extensions: 2665
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 121
Number of HSP's successfully gapped in prelim test: 154
Number of HSP's that attempted gapping in prelim test: 2315
Number of HSP's gapped (non-prelim): 488
length of query: 222
length of database: 18,247,518
effective HSP length: 98
effective length of query: 124
effective length of database: 14,536,650
effective search space: 1802544600
effective search space used: 1802544600
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.