Search of human proteins with 4507569

Search of human proteins with 4507569

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507569 tumor necrosis factor receptor superfamily, member
25 isoform 2 precursor [Homo sapiens]
         (417 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507569 tumor necrosis factor receptor superfamily, member 25...   899   0.0  
gi|23200021 tumor necrosis factor receptor superfamily, member 2...   847   0.0  
gi|23200023 tumor necrosis factor receptor superfamily, member 2...   800   0.0  
gi|23200025 tumor necrosis factor receptor superfamily, member 2...   772   0.0  
gi|89142745 tumor necrosis factor receptor superfamily, member 2...   409   e-114
gi|23200031 tumor necrosis factor receptor superfamily, member 2...   376   e-104
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi...   127   2e-29
gi|23200041 tumor necrosis factor receptor superfamily, member 1...    73   4e-13
gi|23510423 tumor necrosis factor receptor superfamily, member 6...    65   9e-11
gi|23510421 tumor necrosis factor receptor superfamily, member 6...    65   9e-11
gi|4507583 tumor necrosis factor receptor superfamily, member 6 ...    65   9e-11
gi|224494019 tumor necrosis factor receptor superfamily, member ...    64   2e-10
gi|4507565 tumor necrosis factor receptor superfamily, member 11...    59   1e-08
gi|224494026 tumor necrosis factor receptor superfamily, member ...    57   4e-08
gi|4507587 tumor necrosis factor receptor superfamily, member 7 ...    54   3e-07
gi|4505039 lymphotoxin beta receptor [Homo sapiens]                    54   3e-07
gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]             50   5e-06
gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi...    49   8e-06
gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]            48   2e-05
gi|7657039 tumor necrosis factor receptor superfamily, member 21...    47   3e-05
gi|148743793 osteoprotegerin precursor [Homo sapiens]                  45   9e-05
gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens]    45   9e-05
gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo sapi...    45   9e-05
gi|23238204 tumor necrosis factor receptor superfamily, member 1...    45   1e-04
gi|23238202 tumor necrosis factor receptor superfamily, member 1...    45   1e-04
gi|110611156 laminin, gamma 3 precursor [Homo sapiens]                 44   2e-04
gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]    44   4e-04
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]               43   6e-04
gi|239755070 PREDICTED: similar to proprotein convertase subtili...    42   8e-04
gi|145309326 laminin, gamma 1 precursor [Homo sapiens]                 42   0.001

>gi|4507569 tumor necrosis factor receptor superfamily, member 25
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score =  899 bits (2323), Expect = 0.0
 Identities = 417/417 (100%), Positives = 417/417 (100%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 240
           TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
Sbjct: 181 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 240

Query: 241 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 300
           MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
Sbjct: 241 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 300

Query: 301 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 360
           DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
Sbjct: 301 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 360

Query: 361 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 417
           IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
Sbjct: 361 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 417


>gi|23200021 tumor necrosis factor receptor superfamily, member 25
           isoform 1 precursor [Homo sapiens]
          Length = 426

 Score =  847 bits (2189), Expect = 0.0
 Identities = 403/426 (94%), Positives = 406/426 (95%), Gaps = 9/426 (2%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TS--TLGSCPERCA------AVCGWRQ-MFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 231
           T   +L   P          +V G R  +FWVQVLLAGLVVPLLLGATLTYTYRHCWPHK
Sbjct: 181 TPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHK 240

Query: 232 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 291
           PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA
Sbjct: 241 PLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEA 300

Query: 292 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 351
           LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV
Sbjct: 301 LCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFV 360

Query: 352 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 411
           RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS
Sbjct: 361 RTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRS 420

Query: 412 RLQRGP 417
           RLQRGP
Sbjct: 421 RLQRGP 426


>gi|23200023 tumor necrosis factor receptor superfamily, member 25
           isoform 3 precursor [Homo sapiens]
          Length = 380

 Score =  800 bits (2066), Expect = 0.0
 Identities = 379/417 (90%), Positives = 380/417 (91%), Gaps = 37/417 (8%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 240
           TSTLGSCPERCAAVCGWRQ                                     +EAG
Sbjct: 181 TSTLGSCPERCAAVCGWRQ-------------------------------------NEAG 203

Query: 241 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 300
           MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
Sbjct: 204 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 263

Query: 301 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 360
           DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
Sbjct: 264 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 323

Query: 361 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 417
           IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
Sbjct: 324 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 380


>gi|23200025 tumor necrosis factor receptor superfamily, member 25
           isoform 4 precursor [Homo sapiens]
          Length = 372

 Score =  772 bits (1993), Expect = 0.0
 Identities = 372/417 (89%), Positives = 372/417 (89%), Gaps = 45/417 (10%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA       
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA------- 53

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
                                                 ASQVALENCSAVADTRCGCKPG
Sbjct: 54  --------------------------------------ASQVALENCSAVADTRCGCKPG 75

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 76  WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 135

Query: 181 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 240
           TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG
Sbjct: 136 TSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAG 195

Query: 241 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 300
           MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW
Sbjct: 196 MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSW 255

Query: 301 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 360
           DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE
Sbjct: 256 DQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAE 315

Query: 361 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 417
           IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP
Sbjct: 316 IEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP 372


>gi|89142745 tumor necrosis factor receptor superfamily, member 25
           isoform 12 precursor [Homo sapiens]
          Length = 181

 Score =  409 bits (1051), Expect = e-114
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP
Sbjct: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60

Query: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120
           CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG
Sbjct: 61  CTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPG 120

Query: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180
           WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP
Sbjct: 121 WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCP 180

Query: 181 T 181
           T
Sbjct: 181 T 181


>gi|23200031 tumor necrosis factor receptor superfamily, member 25
           isoform 7 precursor [Homo sapiens]
          Length = 234

 Score =  376 bits (966), Expect = e-104
 Identities = 182/182 (100%), Positives = 182/182 (100%)

Query: 236 ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 295
           ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ
Sbjct: 53  ADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQ 112

Query: 296 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 355
           VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG
Sbjct: 113 VTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLG 172

Query: 356 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 415
           LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR
Sbjct: 173 LREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQR 232

Query: 416 GP 417
           GP
Sbjct: 233 GP 234



 Score =  116 bits (290), Expect = 4e-26
 Identities = 53/53 (100%), Positives = 53/53 (100%)

Query: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53
          MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA
Sbjct: 1  MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPA 53


>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
           sapiens]
          Length = 455

 Score =  127 bits (319), Expect = 2e-29
 Identities = 117/411 (28%), Positives = 159/411 (38%), Gaps = 35/411 (8%)

Query: 29  RSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE 88
           R   C      H +    CC  C  G YL   C  P  ++ C  C   +F A ENH    
Sbjct: 40  RDSVCPQGKYIHPQNNSICCTKCHKGTYLYNDCPGPGQDTDCRECESGSFTASENHLR-H 98

Query: 89  CARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALH 148
           C  C  C ++  QV + +C+   DT CGC+       Q     S + F C  C  C  L+
Sbjct: 99  CLSCSKCRKEMGQVEISSCTVDRDTVCGCRKN-----QYRHYWSENLFQCFNCSLC--LN 151

Query: 149 RHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLG-SCPERCAA----VCGWRQ---- 199
               L C  +     TC  GF+   + CVSC        C + C      V G       
Sbjct: 152 GTVHLSCQEKQNTVCTCHAGFFLRENECVSCSNCKKSLECTKLCLPQIENVKGTEDSGTT 211

Query: 200 MFWVQVLLAGLVVPLLLGATLTYTYRH---------CWPHKPLVTADEAGMEALTPPPAT 250
           +    V+  GL +  LL   L Y Y+          C    P    +  G       P  
Sbjct: 212 VLLPLVIFFGLCLLSLLFIGLMYRYQRWKSKLYSIVCGKSTPEKEGELEGTTTKPLAPNP 271

Query: 251 HLSPLDS-AHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALG 309
             SP      TL   P  S    +         P +   +  + P    + D + + AL 
Sbjct: 272 SFSPTPGFTPTLGFSPVPSSTFTSSSTYTPGDCPNFAAPRREVAPPYQGA-DPILATALA 330

Query: 310 --PAAAPTLSPESPAGSPAMMLQPGPQ-LYDVMDAVPARRWKEFVRTLGLREAEIEAVEV 366
             P   P    E  A  P  +    P  LY V++ VP  RWKEFVR LGL + EI+ +E+
Sbjct: 331 SDPIPNPLQKWEDSAHKPQSLDTDDPATLYAVVENVPPLRWKEFVRRLGLSDHEIDRLEL 390

Query: 367 EIGR-FRDQQYEMLKRWRQQQP---AGLGAVYAALERMGLDGCVEDLRSRL 413
           + GR  R+ QY ML  WR++ P   A L  +   L  M L GC+ED+   L
Sbjct: 391 QNGRCLREAQYSMLATWRRRTPRREATLELLGRVLRDMDLLGCLEDIEEAL 441


>gi|23200041 tumor necrosis factor receptor superfamily, member 14
           precursor [Homo sapiens]
          Length = 283

 Score = 73.2 bits (178), Expect = 4e-13
 Identities = 60/216 (27%), Positives = 85/216 (39%), Gaps = 31/216 (14%)

Query: 15  LLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCP 74
           L L  LGA       +P      +    +G  CC  C  G+ +K  C E  G + C  CP
Sbjct: 25  LYLTFLGAPCY----APALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTG-TVCEPCP 79

Query: 75  QDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSS 134
             T++A  N   S+C +CQ CD      A  NCS   +  CGC PG F       C+   
Sbjct: 80  PGTYIAHLNGL-SKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF-------CIVQD 131

Query: 135 PFYCQPCLDCGALHRHTRLL---CSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPE-- 189
             +C  C          R+       +DT C  C PG +         P  TL  C    
Sbjct: 132 GDHCAACRAYATSSPGQRVQKGGTESQDTLCQNCPPGTFS--------PNGTLEECQHQT 183

Query: 190 RCA-----AVCGWRQMFWVQVLLAGLVVPLLLGATL 220
           +C+     A  G     WV   L+G +V +++ +T+
Sbjct: 184 KCSWLVTKAGAGTSSSHWVWWFLSGSLVIVIVCSTV 219


>gi|23510423 tumor necrosis factor receptor superfamily, member 6
           isoform 3 precursor [Homo sapiens]
          Length = 220

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|23510421 tumor necrosis factor receptor superfamily, member 6
           isoform 2 precursor [Homo sapiens]
          Length = 314

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|4507583 tumor necrosis factor receptor superfamily, member 6
           isoform 1 precursor [Homo sapiens]
          Length = 335

 Score = 65.5 bits (158), Expect = 9e-11
 Identities = 32/101 (31%), Positives = 45/101 (44%), Gaps = 7/101 (6%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G FC + CP G      CT       C+ C +      + H +S+C RC+ CDE      
Sbjct: 56  GQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGLEV 115

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             NC+   +T+C CKP +F       C S+   +C PC  C
Sbjct: 116 EINCTRTQNTKCRCKPNFF-------CNSTVCEHCDPCTKC 149


>gi|224494019 tumor necrosis factor receptor superfamily, member 10b
           isoform 1 precursor [Homo sapiens]
          Length = 440

 Score = 64.3 bits (155), Expect = 2e-10
 Identities = 89/369 (24%), Positives = 140/369 (37%), Gaps = 57/369 (15%)

Query: 51  CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
           CP GH++     +      C+ C   QD    W +     C RC  CD  + +V L  C+
Sbjct: 81  CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130

Query: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
              +T C C+ G F E         SP  C+ C          R  C R     G C P 
Sbjct: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173

Query: 169 ------FYEHG---DGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGAT 219
                   E G    G V     T+ S P   A+ C    +  + V +A +V+ + +   
Sbjct: 174 SDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLSGII-IGVTVAAVVLIVAVFVC 232

Query: 220 LTYTYRHCWPHKPLVTADEAG----MEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQ 275
            +  ++   P+   + +   G    ++  +  P    + L+   ++L P    E+   VQ
Sbjct: 233 KSLLWKKVLPYLKGICSGGGGDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ 292

Query: 276 LVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQL 335
                  P  P     L P  +    + P+ A        L P +  G P   L+   Q 
Sbjct: 293 ------EPAEPTGVNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QC 341

Query: 336 YD-VMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGA 392
           +D   D VP   W+  +R LGL + EI+  + E    RD  Y ML +W  +  + A +  
Sbjct: 342 FDDFADLVPFDSWEPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHT 401

Query: 393 VYAALERMG 401
           +  ALE +G
Sbjct: 402 LLDALETLG 410


>gi|4507565 tumor necrosis factor receptor superfamily, member 11a
           precursor [Homo sapiens]
          Length = 616

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 51/173 (29%), Positives = 74/173 (42%), Gaps = 17/173 (9%)

Query: 1   MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAP 60
           M  R R    + A LLL  L AR Q   +     C  + H +    CC  C  G Y+ + 
Sbjct: 1   MAPRARRRRPLFALLLLCALLARLQVALQIAP-PCTSEKHYEHLGRCCNKCEPGKYMSSK 59

Query: 61  CTEPCGNSTCLVCPQDTFL-AWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKP 119
           CT    +S CL C  D +L +W  +   +C   + CD   + VA+   ++    RC C  
Sbjct: 60  CT-TTSDSVCLPCGPDEYLDSW--NEEDKCLLHKVCDTGKALVAVVAGNSTTPRRCACTA 116

Query: 120 G--WFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFY 170
           G  W  +C+  +  +     C P L  GA H     L   +DT C  CL G++
Sbjct: 117 GYHWSQDCECCRRNTE----CAPGL--GAQHP----LQLNKDTVCKPCLAGYF 159


>gi|224494026 tumor necrosis factor receptor superfamily, member 10b
           isoform 2 precursor [Homo sapiens]
          Length = 411

 Score = 56.6 bits (135), Expect = 4e-08
 Identities = 84/356 (23%), Positives = 126/356 (35%), Gaps = 60/356 (16%)

Query: 51  CPAGHYLKAPCTEPCGNSTCLVCP--QDTFLAWENHHNSECARCQACDEQASQVALENCS 108
           CP GH++     +      C+ C   QD    W +     C RC  CD  + +V L  C+
Sbjct: 81  CPPGHHISEDGRD------CISCKYGQDYSTHWNDL--LFCLRCTRCD--SGEVELSPCT 130

Query: 109 AVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPG 168
              +T C C+ G F E         SP  C+ C          R  C R     G C P 
Sbjct: 131 TTRNTVCQCEEGTFRE-------EDSPEMCRKC----------RTGCPRGMVKVGDCTPW 173

Query: 169 FYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCW 228
                        S +    +    + G      V ++   +   LL    L Y    C 
Sbjct: 174 -------------SDIECVHKESGIIIGVTVAAVVLIVAVFVCKSLLWKKVLPYLKGICS 220

Query: 229 PHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPET 288
                   D   ++  +  P    + L+   ++L P    E+   VQ       P  P  
Sbjct: 221 GGG----GDPERVDRSSQRPGAEDNVLNEIVSILQPTQVPEQEMEVQ------EPAEPTG 270

Query: 289 QEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYD-VMDAVPARRW 347
              L P  +    + P+ A        L P +  G P   L+   Q +D   D VP   W
Sbjct: 271 VNMLSPGESEHLLE-PAEAERSQRRRLLVPANE-GDPTETLR---QCFDDFADLVPFDSW 325

Query: 348 KEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRW--RQQQPAGLGAVYAALERMG 401
           +  +R LGL + EI+  + E    RD  Y ML +W  +  + A +  +  ALE +G
Sbjct: 326 EPLMRKLGLMDNEIKVAKAEAAGHRDTLYTMLIKWVNKTGRDASVHTLLDALETLG 381


>gi|4507587 tumor necrosis factor receptor superfamily, member 7
           precursor [Homo sapiens]
          Length = 260

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 24/92 (26%), Positives = 41/92 (44%), Gaps = 5/92 (5%)

Query: 44  GLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVA 103
           G  CC+ C  G +L   C +    + C  C      + ++H    C  C+ C+   S + 
Sbjct: 36  GKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPDHHTRPHCESCRHCN---SGLL 92

Query: 104 LENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135
           + NC+  A+  C C+ GW  +C+  +C    P
Sbjct: 93  VRNCTITANAECACRNGW--QCRDKECTECDP 122


>gi|4505039 lymphotoxin beta receptor [Homo sapiens]
          Length = 435

 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 11/100 (11%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHN--SECARCQACDEQASQVAL 104
           CC  CP G Y+ A C+    ++ C  C ++++     H N  + C  C+ CD       +
Sbjct: 58  CCSRCPPGTYVSAKCSR-IRDTVCATCAENSY---NEHWNYLTICQLCRPCDPVMGLEEI 113

Query: 105 ENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDC 144
             C++   T+C C+PG F      +C      +C+   DC
Sbjct: 114 APCTSKRKTQCRCQPGMFCAAWALECT-----HCELLSDC 148


>gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens]
          Length = 277

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 46/184 (25%), Positives = 70/184 (38%), Gaps = 30/184 (16%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
           CC  C  G  L + CTE    + CL C +  FL   N   + C + + CD        + 
Sbjct: 37  CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
            ++  DT C C+ GW        C S +   C+ C+    C       ++     DT C 
Sbjct: 95  GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144

Query: 164 TCLPGFYEHGDGC-------VSCPTSTL---GSCPERCAAVCGWRQMFWVQVLLAGLVVP 213
            C  GF+ +            SC T  L    +   +   VCG +       L A +V+P
Sbjct: 145 PCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVCGPQDR-----LRALVVIP 199

Query: 214 LLLG 217
           ++ G
Sbjct: 200 IIFG 203


>gi|4507577 tumor necrosis factor receptor 2 precursor [Homo
           sapiens]
          Length = 461

 Score = 48.9 bits (115), Expect = 8e-06
 Identities = 33/137 (24%), Positives = 53/137 (38%), Gaps = 11/137 (8%)

Query: 38  DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDE 97
           +++ +    CC  C  G + K  CT+   ++ C  C   T+    N        C +C  
Sbjct: 44  EYYDQTAQMCCSKCSPGQHAKVFCTKT-SDTVCDSCEDSTYTQLWNW----VPECLSCGS 98

Query: 98  QAS--QVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLC 155
           + S  QV  + C+   +  C C+PGW+  C +S+        C P   C       R   
Sbjct: 99  RCSSDQVETQACTREQNRICTCRPGWY--CALSK--QEGCRLCAPLRKCRPGFGVARPGT 154

Query: 156 SRRDTDCGTCLPGFYEH 172
              D  C  C PG + +
Sbjct: 155 ETSDVVCKPCAPGTFSN 171


>gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens]
          Length = 203

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 15/129 (11%)

Query: 47  CCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN 106
           CC  C  G  L + CTE    + CL C +  FL   N   + C + + CD        + 
Sbjct: 37  CCSLCQPGQKLVSDCTE-FTETECLPCGESEFLDTWNRE-THCHQHKYCDPNLGLRVQQK 94

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCL---DCGALHRHTRLLCSRRDTDCG 163
            ++  DT C C+ GW        C S +   C+ C+    C       ++     DT C 
Sbjct: 95  GTSETDTICTCEEGW-------HCTSEA---CESCVLHRSCSPGFGVKQIATGVSDTICE 144

Query: 164 TCLPGFYEH 172
            C  GF+ +
Sbjct: 145 PCPVGFFSN 153


>gi|7657039 tumor necrosis factor receptor superfamily, member 21
           precursor [Homo sapiens]
          Length = 655

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 25/77 (32%), Positives = 32/77 (41%), Gaps = 7/77 (9%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALEN- 106
           C  CPAG Y+   CT       C  CP  TF      H +   +C  C +      +E  
Sbjct: 67  CDKCPAGTYVSEHCTNT-SLRVCSSCPVGTF----TRHENGIEKCHDCSQPCPWPMIEKL 121

Query: 107 -CSAVADTRCGCKPGWF 122
            C+A+ D  C C PG F
Sbjct: 122 PCAALTDRECTCPPGMF 138


>gi|148743793 osteoprotegerin precursor [Homo sapiens]
          Length = 401

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 34/126 (26%), Positives = 48/126 (38%), Gaps = 15/126 (11%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQ-ACDEQASQVALEN 106
           C  CP G YLK  CT     + C  CP D +     H + EC  C   C E   Q   + 
Sbjct: 41  CDKCPPGTYLKQHCTAK-WKTVCAPCP-DHYYTDSWHTSDECLYCSPVCKE--LQYVKQE 96

Query: 107 CSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCL 166
           C+   +  C CK G ++E +          +C     C       +     R+T C  C 
Sbjct: 97  CNRTHNRVCECKEGRYLEIE----------FCLKHRSCPPGFGVVQAGTPERNTVCKRCP 146

Query: 167 PGFYEH 172
            GF+ +
Sbjct: 147 DGFFSN 152


>gi|33356136 hypothetical protein LOC222223 isoform 2 [Homo sapiens]
          Length = 789

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 42/165 (25%), Positives = 59/165 (35%), Gaps = 21/165 (12%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENC 107
           C  C  G +   P     G+  C VCP++T+         EC RC+  D Q S+     C
Sbjct: 50  CFPCKPGTFSNKP-----GSFNCQVCPRNTY---SEKGAKECIRCKD-DSQFSEEGSSEC 100

Query: 108 SAVADTRCGCKPGWFVECQVSQCVSSSPFY--CQPCLDCGALHRHTRLLCSRRDTDCGTC 165
           +      C  K  + +     +   +   Y   +P +    L    RL  S    DC  C
Sbjct: 101 TERPP--CTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPC 158

Query: 166 LPGFYEHG-DGCVSCPTSTLGS-------CPERCAAVCGWRQMFW 202
            PGFY +G   C  CP  T          CP       G+   +W
Sbjct: 159 NPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGTEPALGFEYKWW 203



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 7/46 (15%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE-CARC 92
           C  CP GHY++    +      C  CP DT+L+    +  E C  C
Sbjct: 378 CVPCPPGHYIEKETNQ------CKECPPDTYLSIHQVYGKEACIPC 417


>gi|218505750 hypothetical protein LOC222223 isoform 1 [Homo
           sapiens]
          Length = 1029

 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 42/165 (25%), Positives = 59/165 (35%), Gaps = 21/165 (12%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENC 107
           C  C  G +   P     G+  C VCP++T+         EC RC+  D Q S+     C
Sbjct: 290 CFPCKPGTFSNKP-----GSFNCQVCPRNTY---SEKGAKECIRCKD-DSQFSEEGSSEC 340

Query: 108 SAVADTRCGCKPGWFVECQVSQCVSSSPFY--CQPCLDCGALHRHTRLLCSRRDTDCGTC 165
           +      C  K  + +     +   +   Y   +P +    L    RL  S    DC  C
Sbjct: 341 TERPP--CTTKDYFQIHTPCDEEGKTQIMYKWIEPKICREDLTDAIRLPPSGEKKDCPPC 398

Query: 166 LPGFYEHG-DGCVSCPTSTLGS-------CPERCAAVCGWRQMFW 202
            PGFY +G   C  CP  T          CP       G+   +W
Sbjct: 399 NPGFYNNGSSSCHPCPPGTFSDGTKECRPCPAGTEPALGFEYKWW 443



 Score = 30.8 bits (68), Expect = 2.4
 Identities = 15/46 (32%), Positives = 21/46 (45%), Gaps = 7/46 (15%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSE-CARC 92
           C  CP GHY++    +      C  CP DT+L+    +  E C  C
Sbjct: 618 CVPCPPGHYIEKETNQ------CKECPPDTYLSIHQVYGKEACIPC 657


>gi|23238204 tumor necrosis factor receptor superfamily, member 19
           isoform 2 precursor [Homo sapiens]
          Length = 417

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90

Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170
           PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122


>gi|23238202 tumor necrosis factor receptor superfamily, member 19
           isoform 1 precursor [Homo sapiens]
          Length = 423

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 27/92 (29%), Positives = 41/92 (44%), Gaps = 7/92 (7%)

Query: 86  NSECARCQACDEQASQVALENCSAVADTRCGCKPGW-----FVECQVSQCVSSSPFY-CQ 139
           + +C + +  D   + V    C    +    C  G+      V C++ +      F  C+
Sbjct: 31  SGDCRQQEFRDRSGNCVPCNQCGPGMELSKECGFGYGEDAQCVTCRLHRFKEDWGFQKCK 90

Query: 140 PCLDCGALHRHTRLLCS-RRDTDCGTCLPGFY 170
           PCLDC  ++R  +  CS   D  CG CLPGFY
Sbjct: 91  PCLDCAVVNRFQKANCSATSDAICGDCLPGFY 122


>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
          Length = 1575

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 48/176 (27%), Positives = 59/176 (33%), Gaps = 37/176 (21%)

Query: 27  GTRSPRCDCAGD--FHKKIGLFC----CRGCPAGHYLKAPCTEPCG--NSTCLVCPQDTF 78
           G R  RC+   D  F   +GLF     C  C     +       C   +  CL C     
Sbjct: 780 GQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCL---- 835

Query: 79  LAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYC 138
                 HN+    C+ C E     AL    A     C C P   V  Q+          C
Sbjct: 836 ------HNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP---------C 880

Query: 139 QPCL-DCGALHRHTRLLCSRRDTDCGTCLPGFYE--HGDGCVSCPTSTLGSCPERC 191
            P    C  L   T         DC  C PGF++   G GC SC    LGS  ++C
Sbjct: 881 DPVTGQCSCLPHVTA-------RDCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQC 929



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 23/66 (34%), Positives = 30/66 (45%), Gaps = 14/66 (21%)

Query: 138 CQPCLDC---GALHRHT--RLLCSRRDT----DCGTCLPGFYEHGDG----CVSCPTSTL 184
           CQPC DC   G+LH        C+ + T     C  CLPGF+   +G    C   P  +L
Sbjct: 380 CQPC-DCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSL 438

Query: 185 GSCPER 190
            +C  R
Sbjct: 439 DTCDPR 444



 Score = 31.6 bits (70), Expect = 1.4
 Identities = 29/106 (27%), Positives = 37/106 (34%), Gaps = 29/106 (27%)

Query: 115 CGCKPGWFVECQVSQCVSSSPFY------------CQPCL--DCGALHRHTRLLCSRRDT 160
           C C  G+  +     C S +P Y            C PC     G    +T +      T
Sbjct: 673 CSCPTGYTGQF----CESCAPGYKREMPQGGPYASCVPCTCNQHGTCDPNTGICVCSHHT 728

Query: 161 D---CGTCLPGFYEH-----GDGCVSCPTSTLGSC---PERCAAVC 195
           +   C  CLPGFY +      D C  CP     +C   PE    VC
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVC 774


>gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens]
          Length = 955

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 87/364 (23%), Positives = 120/364 (32%), Gaps = 95/364 (26%)

Query: 23  RAQGGTRSPRCDCAGDFHKKIGL--FCCRGCPAGHYLKAPCT----------------EP 64
           +A G     R DC       I +   CC  C AG      CT                +P
Sbjct: 595 QADGSVSCKRTDCVDSCPHPIRIPGQCCPDCSAG------CTYTGRIFYNNETFPSVLDP 648

Query: 65  CGNSTCLV---------CPQDTFLAWENHHNSECAR-CQACDEQASQVALENCSAVAD-- 112
           C +  CL+         CP      +  H + EC   C+ C+ +  +VA      + D  
Sbjct: 649 CLSCICLLGSVACSPVDCP--ITCTYPFHPDGECCPVCRDCNYEGRKVANGQVFTLDDEP 706

Query: 113 -TRCGCKPGWF----VECQVS---------QCVSSSPFYCQPCLDCGALHRHTRLLCSRR 158
            TRC C+ G      V CQ +          C SS P    P  +   L  H  +  S+ 
Sbjct: 707 CTRCTCQLGEVSCEKVPCQRACADPALLPGDCCSSCPDSLSPLEEKQGLSPHGNVAFSK- 765

Query: 159 DTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVP----- 213
               G  L G  E    C SCP     S P R   V    Q+     L+    +P     
Sbjct: 766 ---AGRSLHGDTEAPVNCSSCPGPPTAS-PSR--PVLHLLQLLLRTNLMKTQTLPTSPAG 819

Query: 214 ------LLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDS 267
                 L LG T T+      P +P   A        + PP     PL S      PP +
Sbjct: 820 AHGPHSLALGLTATF------PGEP--GASPRLSPGPSTPPGAPTLPLASPGAPQPPPVT 871

Query: 268 SEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAM 327
            E+                 +  A   Q+   W  LP   L  A+A ++   SP+ +P  
Sbjct: 872 PER-----------------SFSASGAQIVSRWPPLPGTLLTEASALSMMDPSPSKTPIT 914

Query: 328 MLQP 331
           +L P
Sbjct: 915 LLGP 918


>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
          Length = 1044

 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 58/198 (29%), Positives = 70/198 (35%), Gaps = 56/198 (28%)

Query: 26  GGTRSP---RCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPC------------GNSTC 70
           GGT SP    C C   +    GL C   CP+G +    C E C            G+ +C
Sbjct: 455 GGTCSPVDGSCTCKEGWQ---GLDCTLPCPSGTW-GLNCNESCTCANGAACSPIDGSCSC 510

Query: 71  ----------LVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVAD---TRCG- 116
                     L CP  TF    + H  +C+    CD         +C  +A     RC  
Sbjct: 511 TPGWLGDTCELPCPDGTFGLNCSEH-CDCSHADGCDPVTG-----HCCCLAGWTGIRCDS 564

Query: 117 -CKPG-WFVECQVSQCVSSSPFYCQP---CLDCGALHRHTRLLCSRRDTDCGTCLPGFYE 171
            C PG W   C VS C   +   C P     +C    R    LC R       C PGFY 
Sbjct: 565 TCPPGRWGPNCSVS-CSCENGGSCSPEDGSCECAPGFRGP--LCQR------ICPPGFYG 615

Query: 172 HGDGCVS-CPTSTLGSCP 188
           H  GC   CP     S P
Sbjct: 616 H--GCAQPCPLCVHSSRP 631



 Score = 40.0 bits (92), Expect = 0.004
 Identities = 53/194 (27%), Positives = 63/194 (32%), Gaps = 50/194 (25%)

Query: 33  CDCAGDFHKKIGLFCCRGCPAGHYLK-----------APCTEPCGNSTC----------L 71
           C CA  F   +G  C   C AG Y               C+   G+ TC          L
Sbjct: 422 CTCAPGF---MGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTL 478

Query: 72  VCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCV 131
            CP  T   W  + N  C     C   A+      CS + D  C C PGW  +     C 
Sbjct: 479 PCPSGT---WGLNCNESCT----CANGAA------CSPI-DGSCSCTPGWLGDTCELPCP 524

Query: 132 S-------SSPFYCQPCLDCGALHRHTRLLCSRRDTDC-GTCLPGFYEHGDGC-VSCPTS 182
                   S    C     C  +  H   L       C  TC PG +  G  C VSC   
Sbjct: 525 DGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRW--GPNCSVSCSCE 582

Query: 183 TLGSC-PERCAAVC 195
             GSC PE  +  C
Sbjct: 583 NGGSCSPEDGSCEC 596



 Score = 32.7 bits (73), Expect = 0.63
 Identities = 45/188 (23%), Positives = 62/188 (32%), Gaps = 50/188 (26%)

Query: 32  RCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTF------------- 78
           +C C   +   +G  C   CP G +    C++ C       C   T              
Sbjct: 289 QCHCTAGY---MGDRCQEECPFGSF-GFQCSQHCDCHNGGQCSPTTGACECEPGYKGPRC 344

Query: 79  ---LAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSP 135
              L  E  H   C     CD   +     +C  V    C C+PGW            S 
Sbjct: 345 QERLCPEGLHGPGCTLPCPCDADNTI----SCHPVTGA-CTCQPGW------------SG 387

Query: 136 FYCQPCLDCGALHRHTRLLCS-RRDTDCG------TCLPGFYEHGDGC-VSCPTSTLGSC 187
            +C      G      +L C+ +   DC       TC PGF   G+ C VSC   T G  
Sbjct: 388 HHCNESCPVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFM--GEVCAVSCAAGTYG-- 443

Query: 188 PERCAAVC 195
              C+++C
Sbjct: 444 -PNCSSIC 450



 Score = 32.0 bits (71), Expect = 1.1
 Identities = 20/56 (35%), Positives = 24/56 (42%), Gaps = 8/56 (14%)

Query: 146 ALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTL--GSC--PERCAAVCGW 197
           A  R  R +  RR      C PG+YE GD C+   T     G C  P+ C    GW
Sbjct: 73  AYRRGLRTMYRRRSQ----CCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGW 124



 Score = 30.0 bits (66), Expect = 4.1
 Identities = 44/173 (25%), Positives = 57/173 (32%), Gaps = 62/173 (35%)

Query: 24  AQGGTRSP---RCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLA 80
           A  GT SP    C C   F   IG  C + CP G +  A                     
Sbjct: 670 ANNGTCSPIDGSCQC---FPGWIGKDCSQACPPGFWGPA--------------------- 705

Query: 81  WENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQP 140
                   C    +C   AS      CSA  D  C C PGW       +C ++  F+ + 
Sbjct: 706 --------CFHACSCHNGAS------CSA-EDGACHCTPGWTGLFCTQRCPAA--FFGK- 747

Query: 141 CLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGS-CPERCA 192
             DCG      R+   +    C        +H  G  +C T   G  C +RCA
Sbjct: 748 --DCG------RVCQCQNGASC--------DHISGKCTCRTGFTGQHCEQRCA 784



 Score = 29.3 bits (64), Expect = 6.9
 Identities = 51/195 (26%), Positives = 62/195 (31%), Gaps = 33/195 (16%)

Query: 8   CAAVAAALLLVLLGARA-QGGTRSPRCD--CAGDFHKKIGLFCCRGCPAGHYLKAPCTEP 64
           C     AL   + GA     G R  RC+  CA   H   G  C   C   H   A C   
Sbjct: 146 CQCQNGALCNPITGACVCAAGFRGWRCEELCAPGTH---GKGCQLPCQCRH--GASCDPR 200

Query: 65  CGNSTCLVCPQDTFLAWEN-----HHNSECARCQACDEQASQVALENCSAVADTRCGCKP 119
            G   CL  P  T +  E       H + C     C    +      C  +    C C P
Sbjct: 201 AGE--CLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGT------CHHITG-ECACPP 251

Query: 120 GWFVECQVSQCVSSSPFYCQPC-LDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGC-V 177
           GW        C   +  + Q C  DC   H      C      C  C  G+   GD C  
Sbjct: 252 GWTGAVCAQPCPPGT--FGQNCSQDCPCHHGGQ---CDHVTGQC-HCTAGYM--GDRCQE 303

Query: 178 SCPTSTLG-SCPERC 191
            CP  + G  C + C
Sbjct: 304 ECPFGSFGFQCSQHC 318


>gi|239755070 PREDICTED: similar to proprotein convertase
           subtilisin/kexin type 5 [Homo sapiens]
          Length = 853

 Score = 42.4 bits (98), Expect = 8e-04
 Identities = 58/263 (22%), Positives = 98/263 (37%), Gaps = 62/263 (23%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLV-CPQDTFLAWENHHNSEC-ARCQACDEQASQVALE 105
           C+ CP    L         N+TC+  CP+  +   +++  + C + C+ C+ + S+    
Sbjct: 479 CQTCPMNSLLL--------NTTCVKDCPEGYYADEDSNRCAHCHSSCRTCEGRHSR---- 526

Query: 106 NCSAVADTRCGCKPGWF-------VECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRR 158
            C +       C+PGWF       ++C+      +S   C+ C      +R  +     R
Sbjct: 527 QCHS-------CRPGWFQLGKECLLQCREGYYADNSTGRCERC------NRSCKGCQGPR 573

Query: 159 DTDCGTCLPGFY---EHGDGCVSCP--------TSTLGSCPERCAAVCGWRQM-----FW 202
            TDC +C   F+     G+   SCP        T T   C   C    G   +      W
Sbjct: 574 PTDCLSCDRFFFLLRSKGECHRSCPDHYYVEQSTQTCERCHPTCDQCKGKGALNCLSCVW 633

Query: 203 VQVLLAG------LVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLD 256
              L+ G      LV    +G    +    C  H+  +     G +  T  PA  +  +D
Sbjct: 634 SYHLMGGICTSDCLVGEYRVGEGEKFNCEKC--HESCMECKGPGAKNCTLCPANLVLHMD 691

Query: 257 SAHTL----LAPPDSSEKICTVQ 275
            +H L     + P S+++ C  Q
Sbjct: 692 ESHCLHCCNTSDPPSAQECCDCQ 714



 Score = 36.2 bits (82), Expect = 0.057
 Identities = 42/172 (24%), Positives = 60/172 (34%), Gaps = 49/172 (28%)

Query: 48  CRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARC-QACDEQASQVALEN 106
           C  CP G YL A   + C +S    CPQ T   W +  +  C  C +AC   +     + 
Sbjct: 190 CTSCPKGAYLLA---QACVSS----CPQGT---WPSVRSGSCENCTEACAICSGADLCKK 239

Query: 107 CSA-------VADTRC--GCKPGWFVECQVSQCVSSSPFYCQP----CLDCGALH----- 148
           C         + + RC   C  G + E  + +  SS    C+     C  C   H     
Sbjct: 240 CQMQPGHPLFLHEGRCYSKCPEGSYAEDGICERCSSPCRTCEGNATNCHSCEGGHVLHHG 299

Query: 149 -----------------RHTRLLCSR--RDTDCGTCLPGFYEHGDGC-VSCP 180
                            +H   +C     +  C  C+P F+ H D C  SCP
Sbjct: 300 VCQENCPERHVAVEGVCKHCPEMCQDCIHEKTCKECMPEFFLHDDMCHQSCP 351



 Score = 33.5 bits (75), Expect = 0.37
 Identities = 40/177 (22%), Positives = 57/177 (32%), Gaps = 66/177 (37%)

Query: 73  CPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVAD----------TRCGCKPGWF 122
           CP+ T+        SE   C+ACD   S      C    +           +CG  PG++
Sbjct: 64  CPEKTY--------SEAVECKACDSNCSSCDQNGCYWCEEGFFLLGGSCVRKCG--PGFY 113

Query: 123 VECQVSQCVSSSPFYCQPCL-----DCGALHRHTRLL----------------------- 154
            + ++ +C S     C+ C      +C +     +LL                       
Sbjct: 114 GDQEMGECESCHRA-CETCTGPGHDECSSCQEGLQLLRGMCVHATKTQEEGKFWNDILRK 172

Query: 155 ----------CSRRDTDCGTCLPGFYEHGDGCV-SCPTST-----LGSCPERCAAVC 195
                     C+   T C +C  G Y     CV SCP  T      GSC E C   C
Sbjct: 173 LQPCHSSCKTCNGSATLCTSCPKGAYLLAQACVSSCPQGTWPSVRSGSC-ENCTEAC 228


>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
          Length = 1609

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 49/199 (24%), Positives = 64/199 (32%), Gaps = 57/199 (28%)

Query: 48  CRGCPAGHYLKA---------PCTEPC-GNSTCLVCPQDTFLAWENHHNSECA-RCQACD 96
           C  C  G+Y  +         PC  PC G S+C V P+   +   N        RC+ CD
Sbjct: 751 CEKCSDGYYGDSTAGTSSDCQPC--PCPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCD 808

Query: 97  EQASQVALENCSAVADTR-CGCK----PGWFVECQ--VSQCV----SSSPFYCQPCLD-- 143
           +      L     V   R C C     P     C     +C+    +++ FYC  C D  
Sbjct: 809 DGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGF 868

Query: 144 -----------------------------CGALHRHTRLLCSRRDTDCGTCLPGFY--EH 172
                                        C  +      L      DCG C PGFY  + 
Sbjct: 869 FGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQS 928

Query: 173 GDGCVSCPTSTLGSCPERC 191
           G GC  C    LGS   +C
Sbjct: 929 GQGCERCDCHALGSTNGQC 947



 Score = 29.6 bits (65), Expect = 5.3
 Identities = 42/180 (23%), Positives = 64/180 (35%), Gaps = 37/180 (20%)

Query: 22  ARAQGGTRSPRCDCAG---DFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTF 78
           A A+  +    CDC G   + +    L+   G   GH     C +    + C  C ++ F
Sbjct: 331 ATAESASECLPCDCNGRSQECYFDPELYRSTG-HGGHCTN--CQDNTDGAHCERCRENFF 387

Query: 79  LAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFY- 137
               N   S C  C      ++Q     C +    RC CKPG        +C    P + 
Sbjct: 388 RLGNNEACSSC-HCSPVGSLSTQ-----CDSYG--RCSCKPG----VMGDKCDRCQPGFH 435

Query: 138 ------CQPCL--DCGALHRHT----RLLC--SRRDTDCGTCLPGFY----EHGDGCVSC 179
                 C+PC     G++        R +C  +    +C  C PGF+     +  GC  C
Sbjct: 436 SLTEAGCRPCSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPC 495


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.136    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,495,477
Number of Sequences: 37866
Number of extensions: 1138948
Number of successful extensions: 5037
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 30
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 4655
Number of HSP's gapped (non-prelim): 591
length of query: 417
length of database: 18,247,518
effective HSP length: 105
effective length of query: 312
effective length of database: 14,271,588
effective search space: 4452735456
effective search space used: 4452735456
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.