BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|4505393 nerve growth factor receptor precursor [Homo sapiens] (427 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|4505393 nerve growth factor receptor precursor [Homo sapiens] 889 0.0 gi|4507579 tumor necrosis factor receptor superfamily, member 4 ... 75 1e-13 gi|148743793 osteoprotegerin precursor [Homo sapiens] 72 7e-13 gi|23200041 tumor necrosis factor receptor superfamily, member 1... 72 1e-12 gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 71 2e-12 gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] 70 5e-12 gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapi... 70 5e-12 gi|4507565 tumor necrosis factor receptor superfamily, member 11... 64 2e-10 gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] 64 3e-10 gi|22547121 tumor necrosis factor receptor superfamily, member 1... 64 3e-10 gi|14790170 tumor necrosis factor receptor superfamily, member 6... 64 3e-10 gi|4507585 tumor necrosis factor receptor superfamily, member 6b... 64 3e-10 gi|7657039 tumor necrosis factor receptor superfamily, member 21... 64 3e-10 gi|23510423 tumor necrosis factor receptor superfamily, member 6... 55 2e-07 gi|23510421 tumor necrosis factor receptor superfamily, member 6... 55 2e-07 gi|4507583 tumor necrosis factor receptor superfamily, member 6 ... 55 2e-07 gi|22547108 tumor necrosis factor receptor superfamily, member 1... 54 3e-07 gi|4505039 lymphotoxin beta receptor [Homo sapiens] 54 4e-07 gi|4507587 tumor necrosis factor receptor superfamily, member 7 ... 52 8e-07 gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 51 2e-06 gi|224494019 tumor necrosis factor receptor superfamily, member ... 50 5e-06 gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 49 9e-06 gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 49 9e-06 gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 49 9e-06 gi|21361086 tumor necrosis factor receptor superfamily, member 1... 47 3e-05 gi|21264602 laminin alpha 5 [Homo sapiens] 47 3e-05 gi|224494026 tumor necrosis factor receptor superfamily, member ... 46 6e-05 gi|5730095 tumor necrosis factor receptor superfamily, member 9 ... 45 1e-04 gi|108773804 Fraser syndrome 1 [Homo sapiens] 45 1e-04 gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 44 2e-04 >gi|4505393 nerve growth factor receptor precursor [Homo sapiens] Length = 427 Score = 889 bits (2296), Expect = 0.0 Identities = 427/427 (100%), Positives = 427/427 (100%) Query: 1 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN 60 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN Sbjct: 1 MGAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGAN 60 Query: 61 QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG 120 QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG Sbjct: 61 QTVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG 120 Query: 121 RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC 180 RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC Sbjct: 121 RCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC 180 Query: 181 TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ 240 TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ Sbjct: 181 TRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTTVMGSSQ 240 Query: 241 PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK 300 PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK Sbjct: 241 PVVTRGTTDNLIPVYCSILAAVVVGLVAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEK 300 Query: 301 LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR 360 LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR Sbjct: 301 LHSDSGISVDSQSLHDQQPHTQTASGQALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWR 360 Query: 361 HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE 420 HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE Sbjct: 361 HLAGELGYQPEHIDSFTHEACPVRALLASWATQDSATLDALLAALRRIQRADLVESLCSE 420 Query: 421 STATSPV 427 STATSPV Sbjct: 421 STATSPV 427 >gi|4507579 tumor necrosis factor receptor superfamily, member 4 precursor [Homo sapiens] Length = 277 Score = 75.1 bits (183), Expect = 1e-13 Identities = 77/253 (30%), Positives = 102/253 (40%), Gaps = 51/253 (20%) Query: 1 MGAGATGRAMDGPRLLLLLL-LGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA 59 +GA GR GP LLLL LG+S C Y + CC C G G+ C Sbjct: 3 VGARRLGR---GPCAALLLLGLGLSTVTGLH-CVGDTYPSNDRCCHECRPGNGMVSRCSR 58 Query: 60 NQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAP---CVEADDAVCRCAYGYYQ 115 +Q TVC PC ++DVVS ++PCKPCT C L+S S C D VCRC G Sbjct: 59 SQNTVCRPCGPGF-YNDVVS-SKPCKPCTWC-NLRSGSERKQLCTATQDTVCRCRAGTQP 115 Query: 116 DETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCE-DTE 174 ++ K C CP G +S N C P T C + Sbjct: 116 LDSY---------------------KPGVDCAPCPPGHFSPGDNQA--CKPWTNCTLAGK 152 Query: 175 RQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDL-IASTVAGVVT 233 L+ + +DA CE+ D A QE + PP + + + T A T Sbjct: 153 HTLQPASNSSDAICED--------------RDPPATQPQETQGPPARPITVQPTEAWPRT 198 Query: 234 TVMGSSQPVVTRG 246 + S++PV G Sbjct: 199 SQGPSTRPVEVPG 211 >gi|148743793 osteoprotegerin precursor [Homo sapiens] Length = 401 Score = 72.4 bits (176), Expect = 7e-13 Identities = 50/161 (31%), Positives = 72/161 (44%), Gaps = 11/161 (6%) Query: 18 LLLLGVSLGGAKEACPTGLYTHSGE------CCKACNLGEGVAQPCGAN-QTVCEPCLDS 70 L+ L +S+ + Y H E C C G + Q C A +TVC PC D Sbjct: 9 LVFLDISIKWTTQETFPPKYLHYDEETSHQLLCDKCPPGTYLKQHCTAKWKTVCAPCPDH 68 Query: 71 VTFSDVVSATEPCKPCTE-CVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCE 129 ++D ++ C C+ C LQ + C + VC C G Y + C R C Sbjct: 69 Y-YTDSWHTSDECLYCSPVCKELQYVKQECNRTHNRVCECKEGRYLEIEF--CLKHRSCP 125 Query: 130 AGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170 G G+V + ++NTVC+ CPDG +S+E + PC T C Sbjct: 126 PGFGVVQAGTPERNTVCKRCPDGFFSNETSSKAPCRKHTNC 166 Score = 57.4 bits (137), Expect = 2e-08 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 9/100 (9%) Query: 111 YGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT-V 169 Y +Y +ET+ + C C G+ L C K TVC CPD Y+D + D CL C+ V Sbjct: 28 YLHYDEETSHQL-LCDKCPPGTYLKQHCTAKWKTVCAPCPDHYYTDSWHTSDECLYCSPV 86 Query: 170 CEDTERQLRECTRWADAECEEIPGRWIT-------RSTPP 202 C++ + +EC R + CE GR++ RS PP Sbjct: 87 CKELQYVKQECNRTHNRVCECKEGRYLEIEFCLKHRSCPP 126 >gi|23200041 tumor necrosis factor receptor superfamily, member 14 precursor [Homo sapiens] Length = 283 Score = 72.0 bits (175), Expect = 1e-12 Identities = 50/163 (30%), Positives = 73/163 (44%), Gaps = 14/163 (8%) Query: 15 LLLLLLLGVSL-GGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA-NQTVCEPCLDSVT 72 +L L LG A +C Y ECC C+ G V + CG TVCEPC Sbjct: 24 VLYLTFLGAPCYAPALPSCKEDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPPGTY 83 Query: 73 FSDV--VSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTG-RCEACRV-- 127 + + +S C+ C +GL++ S C ++AVC C+ G++ G C ACR Sbjct: 84 IAHLNGLSKCLQCQMCDPAMGLRA-SRNCSRTENAVCGCSPGHFCIVQDGDHCAACRAYA 142 Query: 128 -CEAGSGLVFSCQDKQNTVCEECPDGTYS-----DEANHVDPC 164 G + + Q+T+C+ CP GT+S +E H C Sbjct: 143 TSSPGQRVQKGGTESQDTLCQNCPPGTFSPNGTLEECQHQTKC 185 Score = 58.2 bits (139), Expect = 1e-08 Identities = 34/106 (32%), Positives = 46/106 (43%), Gaps = 8/106 (7%) Query: 92 LQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPD 151 L + APC C+ +DE E C C G + +C + TVCE CP Sbjct: 27 LTFLGAPCYAPALPSCK------EDEYPVGSECCPKCSPGYRVKEACGELTGTVCEPCPP 80 Query: 152 GTYSDEANHVDPCLPCTVCEDTE--RQLRECTRWADAECEEIPGRW 195 GTY N + CL C +C+ R R C+R +A C PG + Sbjct: 81 GTYIAHLNGLSKCLQCQMCDPAMGLRASRNCSRTENAVCGCSPGHF 126 >gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapiens] Length = 455 Score = 70.9 bits (172), Expect = 2e-12 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 36/205 (17%) Query: 13 PRLLLLLLLGVSLGGA-------------KEACPTGLYTH---SGECCKACNLGEGVAQP 56 P +LL LL+G+ G CP G Y H + CC C+ G + Sbjct: 12 PLVLLELLVGIYPSGVIGLVPHLGDREKRDSVCPQGKYIHPQNNSICCTKCHKGTYLYND 71 Query: 57 C-GANQ-TVCEPCLDSVTFSDVVSATEPCKPCTEC---VGLQSMSAPCVEADDAVCRCA- 110 C G Q T C C +S +F+ + C C++C +G +S+ C D VC C Sbjct: 72 CPGPGQDTDCREC-ESGSFTASENHLRHCLSCSKCRKEMGQVEISS-CTVDRDTVCGCRK 129 Query: 111 --YGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT 168 Y +Y E +C C +C G+ + SCQ+KQNTVC C G + E + C+ C+ Sbjct: 130 NQYRHYWSENLFQCFNCSLCLNGT-VHLSCQEKQNTVC-TCHAGFFLRE----NECVSCS 183 Query: 169 VCEDTERQLRECTRWADAECEEIPG 193 C ++ ECT+ + E + G Sbjct: 184 NC----KKSLECTKLCLPQIENVKG 204 >gi|4507581 CD40 antigen isoform 1 precursor [Homo sapiens] Length = 277 Score = 69.7 bits (169), Expect = 5e-12 Identities = 48/166 (28%), Positives = 74/166 (44%), Gaps = 12/166 (7%) Query: 31 ACPTGLYTHSGECCKACNLGEGVAQPCGA-NQTVCEPCLDSVTFSDVVSATEPC---KPC 86 AC Y + +CC C G+ + C +T C PC +S F D + C K C Sbjct: 25 ACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGES-EFLDTWNRETHCHQHKYC 83 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC---RVCEAGSGLVFSCQDKQN 143 +GL+ E D +C C G++ T+ CE+C R C G G+ + Sbjct: 84 DPNLGLRVQQKGTSETD-TICTCEEGWHC--TSEACESCVLHRSCSPGFGVKQIATGVSD 140 Query: 144 TVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLREC-TRWADAEC 188 T+CE CP G +S+ ++ + C P T CE + +++ T D C Sbjct: 141 TICEPCPVGFFSNVSSAFEKCHPWTSCETKDLVVQQAGTNKTDVVC 186 >gi|4507577 tumor necrosis factor receptor 2 precursor [Homo sapiens] Length = 461 Score = 69.7 bits (169), Expect = 5e-12 Identities = 52/188 (27%), Positives = 75/188 (39%), Gaps = 19/188 (10%) Query: 43 CCKACNLGEGVAQPCG-ANQTVCEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCV 100 CC C+ G+ C + TVC+ C DS T++ + + C C + C Q + C Sbjct: 53 CCSKCSPGQHAKVFCTKTSDTVCDSCEDS-TYTQLWNWVPECLSCGSRCSSDQVETQACT 111 Query: 101 EADDAVCRCAYGYY----QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSD 156 + +C C G+Y + E C R C G G+ + + VC+ C GT+S+ Sbjct: 112 REQNRICTCRPGWYCALSKQEGCRLCAPLRKCRPGFGVARPGTETSDVVCKPCAPGTFSN 171 Query: 157 EANHVDPCLPCTVCE----------DTERQLRECTRWADAECEEIPGRWITRS--TPPEG 204 + D C P +C D TR +P TRS T P Sbjct: 172 TTSSTDICRPHQICNVVAIPGNASMDAVCTSTSPTRSMAPGAVHLPQPVSTRSQHTQPTP 231 Query: 205 SDSTAPST 212 STAPST Sbjct: 232 EPSTAPST 239 Score = 55.1 bits (131), Expect = 1e-07 Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPC- 167 C Y D+T C C C G C +TVC+ C D TY+ N V CL C Sbjct: 40 CRLREYYDQTAQMC--CSKCSPGQHAKVFCTKTSDTVCDSCEDSTYTQLWNWVPECLSCG 97 Query: 168 TVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAP 210 + C + + + CTR + C PG W + EG AP Sbjct: 98 SRCSSDQVETQACTREQNRICTCRPG-WYCALSKQEGCRLCAP 139 >gi|4507565 tumor necrosis factor receptor superfamily, member 11a precursor [Homo sapiens] Length = 616 Score = 64.3 bits (155), Expect = 2e-10 Identities = 54/189 (28%), Positives = 77/189 (40%), Gaps = 18/189 (9%) Query: 17 LLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGA-NQTVCEPC-----LDS 70 LL L V+L A Y H G CC C G+ ++ C + +VC PC LDS Sbjct: 20 LLARLQVALQIAPPCTSEKHYEHLGRCCNKCEPGKYMSSKCTTTSDSVCLPCGPDEYLDS 79 Query: 71 VTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACR---V 127 D + C V + + ++ C C GY+ + CE CR Sbjct: 80 WNEEDKCLLHKVCDTGKALVAVVAGNSTTPRR----CACTAGYHWSQD---CECCRRNTE 132 Query: 128 CEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQL-RECTRWADA 186 C G G Q ++TVC+ C G +SD + D C P T C +++ T +DA Sbjct: 133 CAPGLGAQHPLQLNKDTVCKPCLAGYFSDAFSSTDKCRPWTNCTFLGKRVEHHGTEKSDA 192 Query: 187 EC-EEIPGR 194 C +P R Sbjct: 193 VCSSSLPAR 201 Score = 29.3 bits (64), Expect = 7.1 Identities = 42/179 (23%), Positives = 65/179 (36%), Gaps = 27/179 (15%) Query: 100 VEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEE-----CPDGTY 154 V +D++ +C G ++T E+C E ++ +N + +E CP Sbjct: 380 VGENDSLSQCFTG---TQSTVGSESCNCTEPLCRTDWTPMSSENYLQKEVDSGHCPHWAA 436 Query: 155 SDEANHVDPCLPCT----------VCEDTERQLRECTRWADAECEEIPGRWITRSTPPEG 204 S N D C C V L +C EE R R P +G Sbjct: 437 SPSPNWADVCTGCRNPPGEDCEPLVGSPKRGPLPQCAYGMGLPPEEEASRTEARDQPEDG 496 Query: 205 SDSTAPSTQEPEA-----PPEQDLIASTVAG-VVTTVMGSSQPVVTRGTTDNLIPVYCS 257 +D PS+ A P Q + V G +T + S Q + +G ++I VY S Sbjct: 497 ADGRLPSSARAGAGSGSSPGGQSPASGNVTGNSNSTFISSGQVMNFKG---DIIVVYVS 552 >gi|23312371 CD40 antigen isoform 2 precursor [Homo sapiens] Length = 203 Score = 63.9 bits (154), Expect = 3e-10 Identities = 43/145 (29%), Positives = 65/145 (44%), Gaps = 11/145 (7%) Query: 31 ACPTGLYTHSGECCKACNLGEGVAQPCGA-NQTVCEPCLDSVTFSDVVSATEPC---KPC 86 AC Y + +CC C G+ + C +T C PC +S F D + C K C Sbjct: 25 ACREKQYLINSQCCSLCQPGQKLVSDCTEFTETECLPCGES-EFLDTWNRETHCHQHKYC 83 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC---RVCEAGSGLVFSCQDKQN 143 +GL+ E D +C C G++ T+ CE+C R C G G+ + Sbjct: 84 DPNLGLRVQQKGTSETD-TICTCEEGWHC--TSEACESCVLHRSCSPGFGVKQIATGVSD 140 Query: 144 TVCEECPDGTYSDEANHVDPCLPCT 168 T+CE CP G +S+ ++ + C P T Sbjct: 141 TICEPCPVGFFSNVSSAFEKCHPWT 165 Score = 37.7 bits (86), Expect = 0.020 Identities = 33/92 (35%), Positives = 41/92 (44%), Gaps = 9/92 (9%) Query: 32 CPTGLYTHSGEC--C---KACNLGEGVAQ-PCGANQTVCEPCLDSVTFSDVVSATEPCKP 85 C G + S C C ++C+ G GV Q G + T+CEPC FS+V SA E C P Sbjct: 105 CEEGWHCTSEACESCVLHRSCSPGFGVKQIATGVSDTICEPCPVGF-FSNVSSAFEKCHP 163 Query: 86 CTECVG-LQSMSAPCVEADDAVCR-CAYGYYQ 115 T G +S D VC G YQ Sbjct: 164 WTRSPGSAESPGGDPHHLRDPVCHPLGAGLYQ 195 Score = 30.8 bits (68), Expect = 2.5 Identities = 13/49 (26%), Positives = 20/49 (40%) Query: 123 EACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCE 171 + C +C+ G LV C + T C C + + D N C C+ Sbjct: 36 QCCSLCQPGQKLVSDCTEFTETECLPCGESEFLDTWNRETHCHQHKYCD 84 >gi|22547121 tumor necrosis factor receptor superfamily, member 10c precursor [Homo sapiens] Length = 259 Score = 63.9 bits (154), Expect = 3e-10 Identities = 49/194 (25%), Positives = 72/194 (37%), Gaps = 46/194 (23%) Query: 51 EGVAQPCGANQT----VCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAV 106 +G P G++++ C PC + V +++ + C PCT C Q + C D V Sbjct: 49 KGEECPAGSHRSEHTGACNPCTEGVDYTNASNNEPSCFPCTVCKSDQKHKSSCTMTRDTV 108 Query: 107 CRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLP 166 C+C G +++E + E CR C CP G Sbjct: 109 CQCKEGTFRNENSP--EMCR------------------KCSRCPSG-------------- 134 Query: 167 CTVCEDTERQLRECTRWADAECEEIPGRWITRSTP-PEGSDSTAPSTQEPEAPPEQDLIA 225 E Q+ CT W D +C E G T TP E + +T+P T P A + Sbjct: 135 -------EVQVSNCTSWDDIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSP 187 Query: 226 STVAGVVTTVMGSS 239 T A M +S Sbjct: 188 GTPAPAAEETMTTS 201 >gi|14790170 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 63.5 bits (153), Expect = 3e-10 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 16/176 (9%) Query: 8 RAMDGPRLLLLLLLG-----VSLGGAKEACPTGLY----THSGE--CCKACNLGEGVAQP 56 RA++GP L LL L+ + + + T Y +GE C C G V +P Sbjct: 2 RALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRP 61 Query: 57 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSA-PCVEADDAVCRCAYGYY 114 C + T C PC ++ + E C+ C G + A C + CRC G++ Sbjct: 62 CRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 Query: 115 QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170 G C C G+G++ QNT C+ CP GT+S ++ + C P C Sbjct: 121 AH--AGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC 174 Score = 49.3 bits (116), Expect = 7e-06 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%) Query: 32 CPTGLYTHSGECCK--ACNLGEGVAQPCGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTE 88 C TG + H+G C + +C G GV P +Q T C+PC TFS S++E C+P Sbjct: 115 CRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPG-TFSASSSSSEQCQPHRN 173 Query: 89 CVGL-QSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC 125 C L +++ P + D +C G+ E C Sbjct: 174 CTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211 >gi|4507585 tumor necrosis factor receptor superfamily, member 6b [Homo sapiens] Length = 300 Score = 63.5 bits (153), Expect = 3e-10 Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 16/176 (9%) Query: 8 RAMDGPRLLLLLLLG-----VSLGGAKEACPTGLY----THSGE--CCKACNLGEGVAQP 56 RA++GP L LL L+ + + + T Y +GE C C G V +P Sbjct: 2 RALEGPGLSLLCLVLALPALLPVPAVRGVAETPTYPWRDAETGERLVCAQCPPGTFVQRP 61 Query: 57 CGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSA-PCVEADDAVCRCAYGYY 114 C + T C PC ++ + E C+ C G + A C + CRC G++ Sbjct: 62 CRRDSPTTCGPCPPR-HYTQFWNYLERCRYCNVLCGEREEEARACHATHNRACRCRTGFF 120 Query: 115 QDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC 170 G C C G+G++ QNT C+ CP GT+S ++ + C P C Sbjct: 121 AH--AGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPGTFSASSSSSEQCQPHRNC 174 Score = 49.3 bits (116), Expect = 7e-06 Identities = 31/98 (31%), Positives = 46/98 (46%), Gaps = 5/98 (5%) Query: 32 CPTGLYTHSGECCK--ACNLGEGVAQPCGANQ-TVCEPCLDSVTFSDVVSATEPCKPCTE 88 C TG + H+G C + +C G GV P +Q T C+PC TFS S++E C+P Sbjct: 115 CRTGFFAHAGFCLEHASCPPGAGVIAPGTPSQNTQCQPCPPG-TFSASSSSSEQCQPHRN 173 Query: 89 CVGL-QSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC 125 C L +++ P + D +C G+ E C Sbjct: 174 CTALGLALNVPGSSSHDTLCTSCTGFPLSTRVPGAEEC 211 >gi|7657039 tumor necrosis factor receptor superfamily, member 21 precursor [Homo sapiens] Length = 655 Score = 63.5 bits (153), Expect = 3e-10 Identities = 61/259 (23%), Positives = 93/259 (35%), Gaps = 13/259 (5%) Query: 5 ATGRAMDGPRLLLLLLLGVSLGGAKEACPT-GLYTHSGEC------CKACNLGEGVAQPC 57 AT + G LLL L + ++A G Y H C C G V++ C Sbjct: 21 ATATMIAGSLLLLGFLSTTTAQPEQKASNLIGTYRHVDRATGQVLTCDKCPAGTYVSEHC 80 Query: 58 -GANQTVCEPCLDSVTFSDVVSATEPCKPCTE-CVGLQSMSAPCVEADDAVCRCAYGYYQ 115 + VC C TF+ + E C C++ C PC D C C G +Q Sbjct: 81 TNTSLRVCSSCPVG-TFTRHENGIEKCHDCSQPCPWPMIEKLPCAALTDRECTCPPGMFQ 139 Query: 116 DETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVC-EDTE 174 T C VC G G+ + ++ C++C GT+SD + V C T C Sbjct: 140 SNAT--CAPHTVCPVGWGVRKKGTETEDVRCKQCARGTFSDVPSSVMKCKAYTDCLSQNL 197 Query: 175 RQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAGVVTT 234 ++ T+ D C +P + S P + P E P + + + Sbjct: 198 VVIKPGTKETDNVCGTLPSFSSSTSPSPGTAIFPRPEHMETHEVPSSTYVPKGMNSTESN 257 Query: 235 VMGSSQPVVTRGTTDNLIP 253 S +P V + +P Sbjct: 258 SSASVRPKVLSSIQEGTVP 276 >gi|23510423 tumor necrosis factor receptor superfamily, member 6 isoform 3 precursor [Homo sapiens] Length = 220 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 39 HSGECC-KACNLGEGVAQPCGAN--QTVCEPCLDSVTFSDVVSATEPCKPCTEC---VGL 92 H G+ C K C GE A+ C N + C PC + ++D + C+ C C GL Sbjct: 54 HDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGL 113 Query: 93 QSMSAPCVEADDAVCRCAYGYYQDETT-GRCEACRVCEAGSGLVFSCQDKQNTVCEE 148 + + C + CRC ++ + T C+ C CE G++ C NT C+E Sbjct: 114 E-VEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCKE 167 >gi|23510421 tumor necrosis factor receptor superfamily, member 6 isoform 2 precursor [Homo sapiens] Length = 314 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 39 HSGECC-KACNLGEGVAQPCGAN--QTVCEPCLDSVTFSDVVSATEPCKPCTEC---VGL 92 H G+ C K C GE A+ C N + C PC + ++D + C+ C C GL Sbjct: 54 HDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGL 113 Query: 93 QSMSAPCVEADDAVCRCAYGYYQDETT-GRCEACRVCEAGSGLVFSCQDKQNTVCEE 148 + + C + CRC ++ + T C+ C CE G++ C NT C+E Sbjct: 114 E-VEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCKE 167 >gi|4507583 tumor necrosis factor receptor superfamily, member 6 isoform 1 precursor [Homo sapiens] Length = 335 Score = 54.7 bits (130), Expect = 2e-07 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 10/117 (8%) Query: 39 HSGECC-KACNLGEGVAQPCGAN--QTVCEPCLDSVTFSDVVSATEPCKPCTEC---VGL 92 H G+ C K C GE A+ C N + C PC + ++D + C+ C C GL Sbjct: 54 HDGQFCHKPCPPGERKARDCTVNGDEPDCVPCQEGKEYTDKAHFSSKCRRCRLCDEGHGL 113 Query: 93 QSMSAPCVEADDAVCRCAYGYYQDETT-GRCEACRVCEAGSGLVFSCQDKQNTVCEE 148 + + C + CRC ++ + T C+ C CE G++ C NT C+E Sbjct: 114 E-VEINCTRTQNTKCRCKPNFFCNSTVCEHCDPCTKCE--HGIIKECTLTSNTKCKE 167 >gi|22547108 tumor necrosis factor receptor superfamily, member 10d precursor [Homo sapiens] Length = 386 Score = 53.9 bits (128), Expect = 3e-07 Identities = 86/391 (21%), Positives = 125/391 (31%), Gaps = 110/391 (28%) Query: 29 KEACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTE 88 +E CP G +H E ACN PC + V ++ + C CT Sbjct: 80 EEECPAG--SHRSEYTGACN-----------------PCTEGVDYTIASNNLPSCLLCTV 120 Query: 89 CVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEE 148 C Q+ + C D VC+C G +QD+ + E CR C G Sbjct: 121 CKSGQTNKSSCTTTRDTVCQCEKGSFQDKNSP--EMCRTCRTG----------------- 161 Query: 149 CPDGTYSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDST 208 CP G ++ CT +D +C+ T TP ++ T Sbjct: 162 CPRGMV---------------------KVSNCTPRSDIKCKNESAASSTGKTP--AAEET 198 Query: 209 APSTQEPEAPPEQDLIASTVAGVVTTVMGSSQPVVTRGTTDNLIPVYCSILAAVVVG--L 266 + A P LI V ++ V+ VV I I + G Sbjct: 199 VTTILGMLASPYHYLIIIVVLVIILAVV-----VVGFSCRKKFISYLKGICSGGGGGPER 253 Query: 267 VAYIAFKRWNSCKQNKQGANSRPVNQTPPPEGEKLHSDSGISVDSQSLHDQQPHTQTASG 326 V + F+R SC GA N+T + ++ L Q Q G Sbjct: 254 VHRVLFRR-RSCPSRVPGAEDNARNET---------------LSNRYLQPTQVSEQEIQG 297 Query: 327 QALKGDGGLYSSLPPAKREEVEKLLNGSAGDTWRHLAGELGYQPEHIDSFTHEACPVRAL 386 Q L G+ LP EE ++LL + E C R L Sbjct: 298 QELAELTGVTVELP----EEPQRLLEQAEA----------------------EGCQRRRL 331 Query: 387 LASWATQDSATLDALLAALRRIQRADLVESL 417 L DSA + LL A ++ E++ Sbjct: 332 LVPVNDADSADISTLLDASATLEEGHAKETI 362 >gi|4505039 lymphotoxin beta receptor [Homo sapiens] Length = 435 Score = 53.5 bits (127), Expect = 4e-07 Identities = 36/137 (26%), Positives = 56/137 (40%), Gaps = 8/137 (5%) Query: 43 CCKACNLGEGVAQPCGA-NQTVCEPCLDSVTFS--DVVSATEPCKPCTECVGLQSMSAPC 99 CC C G V+ C TVC C ++ + ++ + C+PC +GL+ + APC Sbjct: 58 CCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEI-APC 116 Query: 100 VEADDAVCRCAYGYYQDETTGRCEACRV---CEAGSGLVFSCQ-DKQNTVCEECPDGTYS 155 CRC G + C C + C G+ + K N C C G + Sbjct: 117 TSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQ 176 Query: 156 DEANHVDPCLPCTVCED 172 + ++ C P T CE+ Sbjct: 177 NTSSPSARCQPHTRCEN 193 >gi|4507587 tumor necrosis factor receptor superfamily, member 7 precursor [Homo sapiens] Length = 260 Score = 52.4 bits (124), Expect = 8e-07 Identities = 46/195 (23%), Positives = 79/195 (40%), Gaps = 35/195 (17%) Query: 20 LLGVSLGGAKEACPTGLYTHSGE-CCKACNLGEGVAQPCGANQTV--CEPCLDSVTFSDV 76 L+G+S A ++CP Y G+ CC+ C G + + C ++ C+PC+ V+FS Sbjct: 15 LVGLSATPAPKSCPERHYWAQGKLCCQMCEPGTFLVKDCDQHRKAAQCDPCIPGVSFSPD 74 Query: 77 VSATEPCKPCTEC-VGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLV 135 C+ C C GL + C +A C C G+ Sbjct: 75 HHTRPHCESCRHCNSGL--LVRNCTITANAECACRNGW---------------------- 110 Query: 136 FSCQDKQNTVCEECPDGTYSDEAN-----HVDPCLPCTVCEDTERQLRECTRWADAECEE 190 C+DK+ T C+ P+ + + ++ H P V E E + + A+ + Sbjct: 111 -QCRDKECTECDPLPNPSLTARSSQALSPHPQPTHLPYVSEMLEARTAGHMQTL-ADFRQ 168 Query: 191 IPGRWITRSTPPEGS 205 +P R ++ PP+ S Sbjct: 169 LPARTLSTHWPPQRS 183 >gi|110611156 laminin, gamma 3 precursor [Homo sapiens] Length = 1575 Score = 50.8 bits (120), Expect = 2e-06 Identities = 49/229 (21%), Positives = 74/229 (32%), Gaps = 46/229 (20%) Query: 31 ACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPCTE-C 89 +CPTG ++G+ C++C G P G C PC + C P T C Sbjct: 674 SCPTG---YTGQFCESCAPGYKREMPQGGPYASCVPC--------TCNQHGTCDPNTGIC 722 Query: 90 VGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEA-GSGLVFSCQDKQNTVCEE 148 V P E RC G+Y + G+ + C+ C G + + + VC Sbjct: 723 VCSHHTEGPSCE------RCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTH 776 Query: 149 CP------------DGTYSDEA---NHVDPCLPCTV-----------CEDTERQLRECTR 182 CP DG + D H PC C C+ C Sbjct: 777 CPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLH 836 Query: 183 WADAE-CEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQDLIASTVAG 230 + CE + + P +D P + P+ + + V G Sbjct: 837 NTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTG 885 Score = 37.4 bits (85), Expect = 0.026 Identities = 27/122 (22%), Positives = 47/122 (38%), Gaps = 23/122 (18%) Query: 64 CEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVC----------RCAYGY 113 CE C ++ D PC+PC +C S+ C + C RC G+ Sbjct: 364 CERCQENFYHWD---PRMPCQPC-DCQSAGSLHLQCDDTGTCACKPTVTGWKCDRCLPGF 419 Query: 114 YQDETTGRCEACR--------VCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCL 165 + + G C C C+ SG ++ + +C+ C GT++ + ++ C Sbjct: 420 HS-LSEGGCRPCTCNPAGSLDTCDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCS 478 Query: 166 PC 167 C Sbjct: 479 SC 480 Score = 33.5 bits (75), Expect = 0.38 Identities = 38/139 (27%), Positives = 47/139 (33%), Gaps = 36/139 (25%) Query: 39 HSGECCKACNLGEGVAQPCGANQTV--CEPCL----DSVTFSDVVSATEPCKPCTECVGL 92 H+ EC ++ +A C N T CE CL D A C PC C G Sbjct: 276 HASEC--GPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCN-CSG- 331 Query: 93 QSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDG 152 S C + +G GRC CR AG CE C + Sbjct: 332 --RSEECTFDRELFRSTGHG-------GRCHHCRDHTAGPH------------CERCQEN 370 Query: 153 TYSDEANHVDPCLPCTVCE 171 Y H DP +PC C+ Sbjct: 371 FY-----HWDPRMPCQPCD 384 Score = 28.9 bits (63), Expect = 9.3 Identities = 29/124 (23%), Positives = 43/124 (34%), Gaps = 34/124 (27%) Query: 41 GECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVS--------------ATEPCKPC 86 G C++C P G+ + C P T V+ + + C+ C Sbjct: 911 GRGCRSCK-----CHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRAC 965 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVC 146 C L + SA C E VCR + Y +C+ C F D T C Sbjct: 966 -RCSPLGAASAQCHENGTCVCRPGFEGY------KCDRCH------DNFFLTAD--GTHC 1010 Query: 147 EECP 150 ++CP Sbjct: 1011 QQCP 1014 >gi|224494019 tumor necrosis factor receptor superfamily, member 10b isoform 1 precursor [Homo sapiens] Length = 440 Score = 49.7 bits (117), Expect = 5e-06 Identities = 40/135 (29%), Positives = 59/135 (43%), Gaps = 12/135 (8%) Query: 109 CAYGYYQDETTGR-----CEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDP 163 C YG QD +T C C C++G + C +NTVC+ C +GT+ +E + + Sbjct: 97 CKYG--QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQ-CEEGTFREE-DSPEM 152 Query: 164 CLPC-TVCEDTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPSTQEPEAPPEQD 222 C C T C ++ +CT W+D EC P ++ S P +P Sbjct: 153 CRKCRTGCPRGMVKVGDCTPWSDIECVHKESGTKHSGEVPAVEETVTSSPGTPASPCSLS 212 Query: 223 --LIASTVAGVVTTV 235 +I TVA VV V Sbjct: 213 GIIIGVTVAAVVLIV 227 Score = 30.8 bits (68), Expect = 2.5 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 146 CEECPDGT-YSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTP 201 C C G YS N + CL CT C+ E +L CT + C+ G + +P Sbjct: 94 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150 >gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] Length = 1816 Score = 48.9 bits (115), Expect = 9e-06 Identities = 54/194 (27%), Positives = 72/194 (37%), Gaps = 30/194 (15%) Query: 2 GAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLY-THSGECCKA--------CNLGEG 52 G+ A GR D P + L A E C G + T SGEC C G G Sbjct: 38 GSSAVGR-QDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG 96 Query: 53 VAQPCGANQTV--CEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCVEADDAV-CR 108 C N T CE CLD + A + C+PC L + + C + AV C Sbjct: 97 YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI 156 Query: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT 168 C Y CE C G+ L+ + C++C D + + DP L Sbjct: 157 CNENY----AGPNCERCAPGYYGNPLLI------GSTCKKC------DCSGNSDPNLIFE 200 Query: 169 VCEDTERQLRECTR 182 C++ Q R C R Sbjct: 201 DCDEVTGQCRNCLR 214 Score = 30.4 bits (67), Expect = 3.2 Identities = 28/107 (26%), Positives = 35/107 (32%), Gaps = 30/107 (28%) Query: 30 EACPTGLYTHS---GECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPC 86 E C G Y + G CK C+ C N ++ F D T C+ C Sbjct: 167 ERCAPGYYGNPLLIGSTCKKCD--------CSGNSD------PNLIFEDCDEVTGQCRNC 212 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSG 133 + C RCA GYY D + C VC G G Sbjct: 213 LR----NTTGFKCE-------RCAPGYYGDARIAK--NCAVCNCGGG 246 >gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] Length = 1823 Score = 48.9 bits (115), Expect = 9e-06 Identities = 54/194 (27%), Positives = 72/194 (37%), Gaps = 30/194 (15%) Query: 2 GAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLY-THSGECCKA--------CNLGEG 52 G+ A GR D P + L A E C G + T SGEC C G G Sbjct: 38 GSSAVGR-QDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG 96 Query: 53 VAQPCGANQTV--CEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCVEADDAV-CR 108 C N T CE CLD + A + C+PC L + + C + AV C Sbjct: 97 YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI 156 Query: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT 168 C Y CE C G+ L+ + C++C D + + DP L Sbjct: 157 CNENY----AGPNCERCAPGYYGNPLLI------GSTCKKC------DCSGNSDPNLIFE 200 Query: 169 VCEDTERQLRECTR 182 C++ Q R C R Sbjct: 201 DCDEVTGQCRNCLR 214 Score = 32.7 bits (73), Expect = 0.65 Identities = 35/144 (24%), Positives = 47/144 (32%), Gaps = 37/144 (25%) Query: 30 EACPTGLYTHS---GECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPC 86 E C G Y + G CK C+ C N ++ F D T C+ C Sbjct: 167 ERCAPGYYGNPLLIGSTCKKCD--------CSGNSD------PNLIFEDCDEVTGQCRNC 212 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVC 146 + C RCA GYY D + C VC G G C ++V Sbjct: 213 LR----NTTGFKCE-------RCAPGYYGDARIAK--NCAVCNCGGG---PC----DSVT 252 Query: 147 EECPDGTYSDEANHVDPCLPCTVC 170 EC + + P + C C Sbjct: 253 GECLEEGFEPPTGMDCPTISCDKC 276 >gi|157419122 laminin, alpha 4 isoform 2 precursor [Homo sapiens] Length = 1816 Score = 48.9 bits (115), Expect = 9e-06 Identities = 54/194 (27%), Positives = 72/194 (37%), Gaps = 30/194 (15%) Query: 2 GAGATGRAMDGPRLLLLLLLGVSLGGAKEACPTGLY-THSGECCKA--------CNLGEG 52 G+ A GR D P + L A E C G + T SGEC C G G Sbjct: 38 GSSAVGR-QDPPETSEPRVALGRLPPAAEKCNAGFFHTLSGECVPCDCNGNSNECLDGSG 96 Query: 53 VAQPCGANQTV--CEPCLDSVTFSDVVSATEPCKPC-TECVGLQSMSAPCVEADDAV-CR 108 C N T CE CLD + A + C+PC L + + C + AV C Sbjct: 97 YCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCI 156 Query: 109 CAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCT 168 C Y CE C G+ L+ + C++C D + + DP L Sbjct: 157 CNENY----AGPNCERCAPGYYGNPLLI------GSTCKKC------DCSGNSDPNLIFE 200 Query: 169 VCEDTERQLRECTR 182 C++ Q R C R Sbjct: 201 DCDEVTGQCRNCLR 214 Score = 30.4 bits (67), Expect = 3.2 Identities = 28/107 (26%), Positives = 35/107 (32%), Gaps = 30/107 (28%) Query: 30 EACPTGLYTHS---GECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKPC 86 E C G Y + G CK C+ C N ++ F D T C+ C Sbjct: 167 ERCAPGYYGNPLLIGSTCKKCD--------CSGNSD------PNLIFEDCDEVTGQCRNC 212 Query: 87 TECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSG 133 + C RCA GYY D + C VC G G Sbjct: 213 LR----NTTGFKCE-------RCAPGYYGDARIAK--NCAVCNCGGG 246 >gi|21361086 tumor necrosis factor receptor superfamily, member 10a [Homo sapiens] Length = 468 Score = 47.4 bits (111), Expect = 3e-05 Identities = 27/125 (21%), Positives = 46/125 (36%), Gaps = 40/125 (32%) Query: 64 CEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCE 123 C C + V +++ + C PCT C + +PC + C+C G ++++ + E Sbjct: 145 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPGTFRNDNS--AE 202 Query: 124 ACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLRECTRW 183 CR C G CP G ++++CT W Sbjct: 203 MCRKCSRG-----------------CPRGMV---------------------KVKDCTPW 224 Query: 184 ADAEC 188 +D EC Sbjct: 225 SDIEC 229 Score = 42.7 bits (99), Expect = 6e-04 Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 146 CEECPDGT-YSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPG 193 C C +G Y++ +N++ CLPCT C+ E + CT + C+ PG Sbjct: 145 CNRCTEGVGYTNASNNLFACLPCTACKSDEEERSPCTTTRNTACQCKPG 193 >gi|21264602 laminin alpha 5 [Homo sapiens] Length = 3695 Score = 47.4 bits (111), Expect = 3e-05 Identities = 53/227 (23%), Positives = 81/227 (35%), Gaps = 48/227 (21%) Query: 32 CPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCL---DSVTFSDVVSATEPCKPCTE 88 C TG + C+ C+ G + Q +C P D + P C E Sbjct: 1471 CATGYWGFPN--CRPCDCGARLCDEL-TGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEE 1527 Query: 89 C----VGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACR------------------ 126 C G+Q ++ P + D C+C + T RC+ C Sbjct: 1528 CNCSGPGIQELTDPTCDTDSGQCKCR----PNVTGRRCDTCSPGFHGYPRCRPCDCHEAG 1583 Query: 127 ----VCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTERQLRECTR 182 VC+ +G + ++ Q C++C GT+S +A + C C TER + Sbjct: 1584 TAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFGATER--CRSSS 1641 Query: 183 WADAECEEIPGRWITRST-----PPEGSDST----APSTQEPEAPPE 220 + E ++ G W+ ST P E T A PEA PE Sbjct: 1642 YTRQEFVDMEG-WVLLSTDRQVVPHERQPGTEMLRADLRHVPEAVPE 1687 Score = 40.8 bits (94), Expect = 0.002 Identities = 25/80 (31%), Positives = 34/80 (42%), Gaps = 10/80 (12%) Query: 98 PCVEADDAVCRCAYGYYQDET---TGRCEACRV------CEAGSGLVFSCQ-DKQNTVCE 147 P D+ CA G+Y+D GRC C+ C GSG+ CQ + + CE Sbjct: 1834 PASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPGSGVCVDCQHNTEGAHCE 1893 Query: 148 ECPDGTYSDEANHVDPCLPC 167 C G S + PC+ C Sbjct: 1894 RCQAGFVSSRDDPSAPCVSC 1913 >gi|224494026 tumor necrosis factor receptor superfamily, member 10b isoform 2 precursor [Homo sapiens] Length = 411 Score = 46.2 bits (108), Expect = 6e-05 Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 10/86 (11%) Query: 109 CAYGYYQDETTGR-----CEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDP 163 C YG QD +T C C C++G + C +NTVC +C +GT+ +E + + Sbjct: 97 CKYG--QDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVC-QCEEGTFREE-DSPEM 152 Query: 164 CLPC-TVCEDTERQLRECTRWADAEC 188 C C T C ++ +CT W+D EC Sbjct: 153 CRKCRTGCPRGMVKVGDCTPWSDIEC 178 Score = 30.8 bits (68), Expect = 2.5 Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 1/57 (1%) Query: 146 CEECPDGT-YSDEANHVDPCLPCTVCEDTERQLRECTRWADAECEEIPGRWITRSTP 201 C C G YS N + CL CT C+ E +L CT + C+ G + +P Sbjct: 94 CISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSP 150 >gi|5730095 tumor necrosis factor receptor superfamily, member 9 precursor [Homo sapiens] Length = 255 Score = 45.4 bits (106), Expect = 1e-04 Identities = 44/172 (25%), Positives = 66/172 (38%), Gaps = 30/172 (17%) Query: 57 CGANQT-VCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQ 115 C N+ +C PC + +FS C C +C G+ C +A C C G++ Sbjct: 37 CDNNRNQICSPCPPN-SFSSA-GGQRTCDICRQCKGVFRTRKECSSTSNAECDCTPGFH- 93 Query: 116 DETTGRC--EACRVCEAGSGLVFSCQDKQNTV---CEECPDGTYSDEANHVDPCLPCTVC 170 C C +CE C+ Q C++C GT++D+ + C P T C Sbjct: 94 ------CLGAGCSMCEQ------DCKQGQELTKKGCKDCCFGTFNDQKRGI--CRPWTNC 139 Query: 171 E-DTERQLRECTRWADAECEEIPGRWITRSTPPEGSDSTAPS-TQEPEAPPE 220 D + L T+ D C P P S T P+ +EP P+ Sbjct: 140 SLDGKSVLVNGTKERDVVCGPSPA-----DLSPGASSVTPPAPAREPGHSPQ 186 Score = 44.7 bits (104), Expect = 2e-04 Identities = 23/78 (29%), Positives = 37/78 (47%), Gaps = 5/78 (6%) Query: 116 DETTGRCEACRVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLPCTVCEDTER 175 + T + C C AG+ C + +N +C CP ++S A C C C+ R Sbjct: 19 ERTRSLQDPCSNCPAGT----FCDNNRNQICSPCPPNSFSS-AGGQRTCDICRQCKGVFR 73 Query: 176 QLRECTRWADAECEEIPG 193 +EC+ ++AEC+ PG Sbjct: 74 TRKECSSTSNAECDCTPG 91 >gi|108773804 Fraser syndrome 1 [Homo sapiens] Length = 4011 Score = 45.1 bits (105), Expect = 1e-04 Identities = 39/154 (25%), Positives = 51/154 (33%), Gaps = 27/154 (17%) Query: 32 CPTGLYTHSGEC------CKAC-NLGEGVAQPCGANQTVCE--PCLDSVTFSDVVSATEP 82 CP+G Y G C C+ C G C N + C + + Sbjct: 846 CPSGYYAERGACKKCHSSCRTCQGRGPFSCSSCDTNLVLSHTGTCSTTCFPGHYLDDNHV 905 Query: 83 CKPCTECVGLQSMSAPCVEADD-------AVCR---CAYGYYQDETTGRCEACR-VCEAG 131 C+PC G A C D C+ CA YY D +T C+ C C A Sbjct: 906 CQPCNTHCGSCDSQASCTSCRDPNKVLLFGECQYESCAPQYYLDFSTNTCKECDWSCSA- 964 Query: 132 SGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCL 165 C T C +C DG + V+ CL Sbjct: 965 ------CSGPLKTDCLQCMDGYVLQDGACVEQCL 992 Score = 41.6 bits (96), Expect = 0.001 Identities = 42/163 (25%), Positives = 57/163 (34%), Gaps = 37/163 (22%) Query: 31 ACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDS--VTFSDVVSATEPCKPCTE 88 AC G C C GEG G VC+ C S S CK E Sbjct: 625 ACSPPKALRQGHCLPRC--GEGFYSDHG----VCKACHSSCLACMGPAPSHCTGCKKPEE 678 Query: 89 CVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLVFSCQDKQNTVC-- 146 + ++ +S + + + + +C +Y E+TG CEAC F C K C Sbjct: 679 GLQVEQLSDVGIPSGECLAQCRAHFYL-ESTGICEACHQ------SCFRCAGKSPHNCTD 731 Query: 147 -------------EECPDGTYSDEANHVDPCLPCTVCEDTERQ 176 +CPDG + E + CT C T RQ Sbjct: 732 CGPSHVLLDGQCLSQCPDGYFHQEGS-------CTECHPTCRQ 767 Score = 39.7 bits (91), Expect = 0.005 Identities = 43/155 (27%), Positives = 54/155 (34%), Gaps = 46/155 (29%) Query: 26 GGAKEACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEPCKP 85 GG + +C G Y G C AC+ CG + C C + D K Sbjct: 541 GGCESSCGKGFYNRQG-TCSACDQS---CDSCGPSSPRCLTCTEKTVLHD-------GKC 589 Query: 86 CTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC-RVCEAGSGLVFS----CQD 140 +EC G GYY D TGRC+ C C + SG S C Sbjct: 590 MSECPG--------------------GYYAD-ATGRCKVCHNSCASCSGPTPSHCTACSP 628 Query: 141 ----KQNTVCEECPDGTYSD----EANHVDPCLPC 167 +Q C +G YSD +A H CL C Sbjct: 629 PKALRQGHCLPRCGEGFYSDHGVCKACH-SSCLAC 662 Score = 30.0 bits (66), Expect = 4.2 Identities = 38/161 (23%), Positives = 51/161 (31%), Gaps = 40/161 (24%) Query: 30 EACPTGLYTH-SGECCKACNLGEGVAQPCGANQTVCEPCLDSVTFSDVVSATEP------ 82 E+C Y S CK C+ G +T C C+D D + Sbjct: 940 ESCAPQYYLDFSTNTCKECDWSCSACS--GPLKTDCLQCMDGYVLQDGACVEQCLSSFYQ 997 Query: 83 ----CK------------PCTECVG-LQSMSAPCVEADDAVCRCAYGYYQDETTGRCEAC 125 CK CT C G + A CV+ C GY+ D +C AC Sbjct: 998 DSGLCKCDSYCLQCQGPHECTRCKGPFLLLEAQCVQ------ECGKGYFADHAKHKCTAC 1051 Query: 126 RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCLP 166 L S +D+ C C G + V C+P Sbjct: 1052 ----PQGCLQCSHRDR----CHLCDHGFFLKSGLCVYNCVP 1084 >gi|38788416 laminin, alpha 1 precursor [Homo sapiens] Length = 3075 Score = 44.3 bits (103), Expect = 2e-04 Identities = 48/191 (25%), Positives = 69/191 (36%), Gaps = 38/191 (19%) Query: 18 LLLLGVSLGGAKEACPTGLYTHS--GECCKAC------------NLGEGVAQPCGANQT- 62 L LG + G E C G Y + + C+AC +L G+ C N T Sbjct: 871 LKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCD-CKPNVTG 929 Query: 63 -VCEPCLDSVTFSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVC----------RCAY 111 C+ CL D + C+PC C S+S C + C RCA+ Sbjct: 930 QQCDQCLHGYYGLD---SGHGCRPCN-CSVAGSVSDGCTDEGQCHCVPGVAGKRCDRCAH 985 Query: 112 GYYQDETTGRCEAC------RVCEAGSGLVFSCQDKQNTVCEECPDGTYSDEANHVDPCL 165 G+Y + G C C C+ +G Q CEEC DG + +A Sbjct: 986 GFYAYQD-GSCTPCDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQAC 1044 Query: 166 PCTVCEDTERQ 176 C++ T + Sbjct: 1045 NCSLVGSTHHR 1055 Score = 41.2 bits (95), Expect = 0.002 Identities = 53/210 (25%), Positives = 75/210 (35%), Gaps = 49/210 (23%) Query: 30 EACPTGLY---THSGECCKAC----NLGEGVAQPCGANQTVCEPCLDSVT---------- 72 E C G Y T GE C C N+ A C + C CL + Sbjct: 829 ERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCADG 888 Query: 73 -FSDVVSATEPCKPCTECVGLQSMSAPCVEADDAVC------------RCAYGYYQDETT 119 + D V+A C+ C EC S SA C + +C +C +GYY ++ Sbjct: 889 FYGDAVTAKN-CRAC-ECHVKGSHSAVC-HLETGLCDCKPNVTGQQCDQCLHGYYGLDSG 945 Query: 120 GRCEACRVCEAGSGLVFSCQDK---------QNTVCEECPDGTYSDEANHVDPCLPCTVC 170 C C AGS + C D+ C+ C G Y+ + PC C Sbjct: 946 HGCRPCNCSVAGS-VSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPC-DCPHT 1003 Query: 171 EDT-ERQLRECT---RWADAECEEI-PGRW 195 ++T + + EC +CEE G W Sbjct: 1004 QNTCDPETGECVCPPHTQGVKCEECEDGHW 1033 Score = 39.3 bits (90), Expect = 0.007 Identities = 36/139 (25%), Positives = 47/139 (33%), Gaps = 28/139 (20%) Query: 56 PCGANQTVCEPCLDSVTFSDVVSATEPCKPCTECVG------LQSMSAPCVEADDAV-C- 107 P G T CE CL D + C+PC EC G + + C V C Sbjct: 712 PQGYTGTSCESCLSGYYRVDGILFGGICQPC-ECHGHAAECNVHGVCIACAHNTTGVHCE 770 Query: 108 RCAYGYYQDE---TTGRCEACR------------VCEAGSGLVFSCQ----DKQNTVCEE 148 +C G+Y + T G C+ C C G C CE Sbjct: 771 QCLPGFYGEPSRGTPGDCQPCACPLTIASNNFSPTCHLNDGDEVVCDWCAPGYSGAWCER 830 Query: 149 CPDGTYSDEANHVDPCLPC 167 C DG Y + + C+PC Sbjct: 831 CADGYYGNPTVPGESCVPC 849 Score = 32.7 bits (73), Expect = 0.65 Identities = 39/152 (25%), Positives = 56/152 (36%), Gaps = 41/152 (26%) Query: 30 EACPTGLYTHSGEC-CKACNLG---------EGVAQPCGANQT----VCEPCLDSVTFSD 75 E C G + + E C+ACN + V C C+ C S+ + D Sbjct: 1026 EECEDGHWGYDAEVGCQACNCSLVGSTHHRCDVVTGHCQCKSKFGGRACDQC--SLGYRD 1083 Query: 76 VVSATEPCKPCTECVGLQSMSAPCVEADDAVCRCAYGYYQDETTGRCEACRVCEAGSGLV 135 C PC +C L+ S + +C C E TG C C+ V Sbjct: 1084 FPD----CVPC-DC-DLRGTSGDACNLEQGLCGCV------EETGACP----CKEN---V 1124 Query: 136 FSCQDKQNTVCEECPDGTYSDEANHVDPCLPC 167 F Q C EC +GT++ A++ C PC Sbjct: 1125 FGPQ------CNECREGTFALRADNPLGCSPC 1150 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.130 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,503,643 Number of Sequences: 37866 Number of extensions: 997383 Number of successful extensions: 4401 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 189 Number of HSP's that attempted gapping in prelim test: 3894 Number of HSP's gapped (non-prelim): 570 length of query: 427 length of database: 18,247,518 effective HSP length: 105 effective length of query: 322 effective length of database: 14,271,588 effective search space: 4595451336 effective search space used: 4595451336 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.