Guide to the Human Genome
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Search of human proteins with 4503489

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4503489 ephrin-B3 precursor [Homo sapiens]
         (340 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4503489 ephrin-B3 precursor [Homo sapiens]                         717   0.0  
gi|4758250 ephrin B2 [Homo sapiens]                                   242   3e-64
gi|4758248 ephrin-B1 precursor [Homo sapiens]                         238   6e-63
gi|27894381 ephrin-A2 precursor [Homo sapiens]                         69   5e-12
gi|33359686 ephrin A4 isoform b [Homo sapiens]                         68   1e-11
gi|4826708 ephrin A3 [Homo sapiens]                                    64   1e-10
gi|33359680 ephrin A1 isoform b precursor [Homo sapiens]               64   2e-10
gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]               63   3e-10
gi|4503487 ephrin-A5 [Homo sapiens]                                    61   2e-09
gi|100913200 ephrin A4 isoform c [Homo sapiens]                        59   5e-09
gi|4885197 ephrin A4 isoform a [Homo sapiens]                          59   6e-09
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    52   8e-07
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    52   8e-07
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    52   8e-07
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    52   8e-07
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           50   3e-06
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       50   4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    48   1e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    48   1e-05
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    47   2e-05
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    47   2e-05
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    47   2e-05
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                45   7e-05
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]         45   7e-05
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               45   7e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      45   9e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    45   9e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    45   9e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    45   9e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      45   9e-05

>gi|4503489 ephrin-B3 precursor [Homo sapiens]
          Length = 340

 Score =  717 bits (1850), Expect = 0.0
 Identities = 340/340 (100%), Positives = 340/340 (100%)

Query: 1   MGPPHSGPGGVRVGALLLLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDL 60
           MGPPHSGPGGVRVGALLLLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDL
Sbjct: 1   MGPPHSGPGGVRVGALLLLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDL 60

Query: 61  LCPRARPPGPHSSPNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEY 120
           LCPRARPPGPHSSPNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEY
Sbjct: 61  LCPRARPPGPHSSPNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEY 120

Query: 121 SPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKP 180
           SPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKP
Sbjct: 121 SPNLWGHEFRSHHDYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKP 180

Query: 181 VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLL 240
           VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLL
Sbjct: 181 VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLL 240

Query: 241 GVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG 300
           GVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG
Sbjct: 241 GVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG 300

Query: 301 GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV 340
           GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV
Sbjct: 301 GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPNIYYKV 340


>gi|4758250 ephrin B2 [Homo sapiens]
          Length = 333

 Score =  242 bits (618), Expect = 3e-64
 Identities = 135/330 (40%), Positives = 187/330 (56%), Gaps = 13/330 (3%)

Query: 14  GALLLLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSS 73
           G L++L    +   + LEP+YWNS+N +F    G VLYPQIGD+LD++CP+       + 
Sbjct: 14  GVLMVLCRTAISKSIVLEPIYWNSSNSKFLPGQGLVLYPQIGDKLDIICPKV---DSKTV 70

Query: 74  PNYEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHH 133
             YE+YK+Y+V   Q  RC        LL C +PD D++FTIKFQE+SPNLWG EF+ + 
Sbjct: 71  GQYEYYKVYMVDKDQADRCTIKKENTPLLNCAKPDQDIKFTIKFQEFSPNLWGLEFQKNK 130

Query: 134 DYYIIATSDGTREGLESLQGGVCLTRGMKVLLRVGQ--SPRGGAVPRKPVSEMPMER-DR 190
           DYYII+TS+G+ EGL++ +GGVC TR MK+L++VGQ  S  G    + P     +E    
Sbjct: 131 DYYIISTSNGSLEGLDNQEGGVCQTRAMKILMKVGQDASSAGSTRNKDPTRRPELEAGTN 190

Query: 191 GAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMC 250
           G + +  P  +  PG  T   ++  +   +    +   AG A G  + ++ +      + 
Sbjct: 191 GRSSTTSPFVKPNPGSSTDGNSAGHSGNNILGSEVALFAGIASGCIIFIVIIITLVVLLL 250

Query: 251 WRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPH 310
             RRR +    +H    S     +    G        +EP ++ I LR    AD  FCPH
Sbjct: 251 KYRRRHRKHSPQHTTTLSLSTLATPKRSGNN----NGSEPSDIIIPLR---TADSVFCPH 303

Query: 311 YEKVSGDYGHPVYIVQDGPPQSPPNIYYKV 340
           YEKVSGDYGHPVYIVQ+ PPQSP NIYYKV
Sbjct: 304 YEKVSGDYGHPVYIVQEMPPQSPANIYYKV 333


>gi|4758248 ephrin-B1 precursor [Homo sapiens]
          Length = 346

 Score =  238 bits (607), Expect = 6e-63
 Identities = 136/329 (41%), Positives = 180/329 (54%), Gaps = 30/329 (9%)

Query: 29  SLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQ 88
           +LEPV W+S N +F +  G V+YP+IGD+LD++CPRA    P     YE+YKLYLV   Q
Sbjct: 31  NLEPVSWSSLNPKFLSGKGLVIYPKIGDKLDIICPRAEAGRP-----YEYYKLYLVRPEQ 85

Query: 89  GRRCEAPPAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGL 148
              C     PN+L+TC+RP+ ++RFTIKFQE+SPN  G EF+ HHDYYI +TS+G+ EGL
Sbjct: 86  AAACSTVLDPNVLVTCNRPEQEIRFTIKFQEFSPNYMGLEFKKHHDYYITSTSNGSLEGL 145

Query: 149 ESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLE-PGKENLPGDP 207
           E+ +GGVC TR MK++++VGQ P      +   S    E D     + + PG     GD 
Sbjct: 146 ENREGGVCRTRTMKIIMKVGQDPNAVTPEQLTTSRPSKEADNTVKMATQAPGSRGSLGDS 205

Query: 208 TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMC----------------W 251
                +   E    P +    +G   G     + +  A GA C                 
Sbjct: 206 DGKHETVNQEEKSGPGASGGSSGDPDGFFNSKVALFAAVGAGCVIFLLIIIFLTVLLLKL 265

Query: 252 RRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHY 311
           R+R  K ++ R     +     S      GG G    EP ++ I LR     +  +CPHY
Sbjct: 266 RKRHRKHTQQR-----AAALSLSTLASPKGGSGTAGTEPSDIIIPLR---TTENNYCPHY 317

Query: 312 EKVSGDYGHPVYIVQDGPPQSPPNIYYKV 340
           EKVSGDYGHPVYIVQ+ PPQSP NIYYKV
Sbjct: 318 EKVSGDYGHPVYIVQEMPPQSPANIYYKV 346


>gi|27894381 ephrin-A2 precursor [Homo sapiens]
          Length = 213

 Score = 69.3 bits (168), Expect = 5e-12
 Identities = 43/117 (36%), Positives = 57/117 (48%), Gaps = 9/117 (7%)

Query: 33  VYWNSANKRFQAE-----GGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGA 87
           VYWN +N RF A      GGY +   I D LD+ CP    P P +    E Y LY+V G 
Sbjct: 39  VYWNRSNPRFHAGAGDDGGGYTVEVSINDYLDIYCPHYGAPLPPAE-RMEHYVLYMVNGE 97

Query: 88  QGRRCEAPPAPNLLLTCDRPDLD---LRFTIKFQEYSPNLWGHEFRSHHDYYIIATS 141
               C+          C+RP      L+F+ KFQ ++P   G EFR  H+YY I+ +
Sbjct: 98  GHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISAT 154


>gi|33359686 ephrin A4 isoform b [Homo sapiens]
          Length = 207

 Score = 68.2 bits (165), Expect = 1e-11
 Identities = 52/163 (31%), Positives = 72/163 (44%), Gaps = 9/163 (5%)

Query: 33  VYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQGRRC 92
           VYWNS+N R    G  V+   + D LD++CP    PGP   P  E + LY+V       C
Sbjct: 30  VYWNSSNPRL-LRGDAVVELGLNDYLDIVCPHYEGPGPPEGP--ETFALYMVDWPGYESC 86

Query: 93  EAP-PAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIA--TSDGTREGLE 149
           +A  P       C  P   ++F+ K Q ++P   G EF     YY I+  T + + + L 
Sbjct: 87  QAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLR 146

Query: 150 SLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGA 192
                 C  R  +VL R   SP GG +P         +R  GA
Sbjct: 147 LQVSVCCKERRARVLPR---SPGGGGIPAACTGGANSDRQDGA 186


>gi|4826708 ephrin A3 [Homo sapiens]
          Length = 238

 Score = 64.3 bits (155), Expect = 1e-10
 Identities = 41/117 (35%), Positives = 56/117 (47%), Gaps = 11/117 (9%)

Query: 33  VYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPG------PHSSPNYEFYKLYLVGG 86
           VYWNS+N+  + EG Y +   + D LD+ CP     G      P      E Y LY+V  
Sbjct: 35  VYWNSSNQHLRREG-YTVQVNVNDYLDIYCPHYNSSGVGPGAGPGPGGGAEQYVLYMVSR 93

Query: 87  AQGRRCEAPPAPNLLLTCDRPDLD---LRFTIKFQEYSPNLWGHEFRSHHDYYIIAT 140
              R C A         C+RP      ++F+ KFQ YS    G+EF + H+YY I+T
Sbjct: 94  NGYRTCNASQGFKRW-ECNRPHAPHSPIKFSEKFQRYSAFSLGYEFHAGHEYYYIST 149


>gi|33359680 ephrin A1 isoform b precursor [Homo sapiens]
          Length = 183

 Score = 63.9 bits (154), Expect = 2e-10
 Identities = 40/129 (31%), Positives = 65/129 (50%), Gaps = 9/129 (6%)

Query: 18  LLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPN-- 75
           LLG+   ++      V+WNS+N +F+ E  Y ++ Q+ D +D++CP       HS  +  
Sbjct: 8   LLGLCCSLAAADRHTVFWNSSNPKFRNED-YTIHVQLNDYVDIICPHYED---HSVADAA 63

Query: 76  YEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDL---RFTIKFQEYSPNLWGHEFRSH 132
            E Y LYLV   + + C+      +   C+RP       + + KFQ ++P   G EF+  
Sbjct: 64  MEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEG 123

Query: 133 HDYYIIATS 141
           H YY I+ S
Sbjct: 124 HSYYYISHS 132


>gi|33359682 ephrin A1 isoform a precursor [Homo sapiens]
          Length = 205

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 9/127 (7%)

Query: 18  LLGVLGLVSGLSLEPVYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPN-- 75
           LLG+   ++      V+WNS+N +F+ E  Y ++ Q+ D +D++CP       HS  +  
Sbjct: 8   LLGLCCSLAAADRHTVFWNSSNPKFRNED-YTIHVQLNDYVDIICPHYED---HSVADAA 63

Query: 76  YEFYKLYLVGGAQGRRCEAPPAPNLLLTCDRPDLDL---RFTIKFQEYSPNLWGHEFRSH 132
            E Y LYLV   + + C+      +   C+RP       + + KFQ ++P   G EF+  
Sbjct: 64  MEQYILYLVEHEEYQLCQPQSKDQVRWQCNRPSAKHGPEKLSEKFQRFTPFTLGKEFKEG 123

Query: 133 HDYYIIA 139
           H YY I+
Sbjct: 124 HSYYYIS 130


>gi|4503487 ephrin-A5 [Homo sapiens]
          Length = 228

 Score = 60.8 bits (146), Expect = 2e-09
 Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 24/202 (11%)

Query: 33  VYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQGRRC 92
           VYWNS+N RFQ  G Y +   I D LD+ CP      P      E Y LY+V       C
Sbjct: 34  VYWNSSNPRFQ-RGDYHIDVCINDYLDVFCPHYEDSVPEDKT--ERYVLYMVNFDGYSAC 90

Query: 93  EAPPAPNLLLTCDRPDLD---LRFTIKFQEYSPNLWGHEFRSHHDYYIIATS---DGTRE 146
           +          C+RP      L+F+ KFQ ++P   G EFR   +Y+ I+++   +G R 
Sbjct: 91  DHTSKGFKRWECNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYISSAIPDNGRRS 150

Query: 147 GLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGD 206
            L+           +KV +R    P    +    V +   + +    +SLEP  + +   
Sbjct: 151 CLK-----------LKVFVR----PTNSCMKTIGVHDRVFDVNDKVENSLEPADDTVHES 195

Query: 207 PTSNATSRGAEGPLPPPSMPAV 228
              +     A+ P  P  + A+
Sbjct: 196 AEPSRGENAAQTPRIPSRLLAI 217


>gi|100913200 ephrin A4 isoform c [Homo sapiens]
          Length = 193

 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 49/159 (30%), Positives = 70/159 (44%), Gaps = 15/159 (9%)

Query: 33  VYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQGRRC 92
           VYWNS+N R    G  V+   + D LD++CP    PGP   P  E + LY+V       C
Sbjct: 30  VYWNSSNPRL-LRGDAVVELGLNDYLDIVCPHYEGPGPPEGP--ETFALYMVDWPGYESC 86

Query: 93  EAP-PAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREGLESL 151
           +A  P       C  P   ++F+ K Q ++P   G EF     YY I+    T E     
Sbjct: 87  QAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVP--TPE----- 139

Query: 152 QGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEM-PMERD 189
             G CL   + V  +    P   + P++P S   P+E +
Sbjct: 140 SSGQCLRLQVSVCCKERNLP---SHPKEPESSQDPLEEE 175


>gi|4885197 ephrin A4 isoform a [Homo sapiens]
          Length = 201

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 42/126 (33%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 33  VYWNSANKRFQAEGGYVLYPQIGDRLDLLCPRARPPGPHSSPNYEFYKLYLVGGAQGRRC 92
           VYWNS+N R    G  V+   + D LD++CP    PGP   P  E + LY+V       C
Sbjct: 30  VYWNSSNPRL-LRGDAVVELGLNDYLDIVCPHYEGPGPPEGP--ETFALYMVDWPGYESC 86

Query: 93  EAP-PAPNLLLTCDRPDLDLRFTIKFQEYSPNLWGHEFRSHHDYYIIATSDGTREG-LES 150
           +A  P       C  P   ++F+ K Q ++P   G EF     YY I+       G    
Sbjct: 87  QAEGPRAYKRWVCSLPFGHVQFSEKIQRFTPFSLGFEFLPGETYYYISVPTPESSGQCLR 146

Query: 151 LQGGVC 156
           LQ  VC
Sbjct: 147 LQVSVC 152


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 48/135 (35%), Positives = 55/135 (40%), Gaps = 24/135 (17%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G E  PG P      RGA GP  P   P V G+ G     L G  G  G    +  R 
Sbjct: 352 EKGDEGTPGPPGP----RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 257 KPSESRHPGPGSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVS 315
           +P +     PGS G  GS GL G  G  GP    PG+  I  R G    PP         
Sbjct: 408 RPGKDAMGTPGSPGCAGSPGLPGSPGPPGP----PGD--IVFRKG----PP--------- 448

Query: 316 GDYGHPVYIVQDGPP 330
           GD+G P Y+   G P
Sbjct: 449 GDHGLPGYLGSPGIP 463



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 47/157 (29%), Positives = 58/157 (36%), Gaps = 13/157 (8%)

Query: 185 PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAG 244
           P ER     H  E G   LPG P +   + G +GP   P  P   G  G     + G  G
Sbjct: 758 PGERGNSGEHG-EIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 245 A------GGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALR 298
           A       G    + RR K      PG     R G  G  G  G+   + E G LG   +
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG---Q 872

Query: 299 GGGAADPPFC--PHYEKVSGDYGHPVYIVQDGPPQSP 333
            G   +P     P  + V G  G P  I   GPP +P
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/170 (28%), Positives = 64/170 (37%), Gaps = 41/170 (24%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G A PR P          G   ++ PG+    G P S   S GA GP  PP         
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG-SPGAPGPPGPPGSH------ 1262

Query: 233  GGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPG 291
                  ++G+ G  G+M             HPGP G  G  G +G  G      R   PG
Sbjct: 1263 ------VIGIKGDKGSM------------GHPGPKGPPGTAGDMGPPG------RLGAPG 1298

Query: 292  ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP-----PQSPPNI 336
              G+    G   DP F   +  V G+ G+P ++   GP     P+ PP +
Sbjct: 1299 TPGLP---GPRGDPGF-QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/185 (30%), Positives = 68/185 (36%), Gaps = 28/185 (15%)

Query: 168 GQSPRGG--AVPRKP-VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS 224
           GQ  R G   +P  P V  +P  +    A S E G +  PGDP S   S G  GP  PP 
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGE-LALSGEKGDQGPPGDPGSPG-SPGPAGPAGPPG 617

Query: 225 M-----PAVAGAAGGLALLLLGVAGAGGAMCWRRRRA----------KPSESRHPGP-GS 268
                 P + G  G     + G  G  G    R   +           P    HPGP G 
Sbjct: 618 YGPQGEPGLQGTQG-----VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGP 672

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDG 328
            G  GSLG  G  G+   + EPG  GI     G   P     +    G  G P  + + G
Sbjct: 673 PGIPGSLGKCGDPGLPGPDGEPGIPGIGF--PGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 329 PPQSP 333
            P  P
Sbjct: 731 LPGKP 735



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/138 (32%), Positives = 55/138 (39%), Gaps = 30/138 (21%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG +   G+P       G +G    P MP + G  G     L G AG  G       R 
Sbjct: 956  EPGLKGFAGNP-------GEKGNRGVPGMPGLKGLKG-----LPGPAGPPGP------RG 997

Query: 257  KPSESRHPG-PGSFGRGGSLG-LGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
                + +PG PG  G  GS+G +G  G  G R    G LG      G A  P  P    +
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFP----GRAGRPGLPGIHGL 1049

Query: 315  SGDYGHPVYI--VQDGPP 330
             GD G P Y    + GPP
Sbjct: 1050 QGDKGEPGYSEGTRPGPP 1067



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/192 (26%), Positives = 68/192 (35%), Gaps = 46/192 (23%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPA 227
           G   + GA  ++   E+  + D G   +  PG + LPG P       G  GP+ PP  P 
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGA--PGPQGLPGPP-------GFPGPVGPPGPPG 201

Query: 228 VAGAAGGLALLLLGVAGAGGAMCWR-----RRRAKPSESRHPGP---------------- 266
             G  G      +G  G  G M  R       R     +  PGP                
Sbjct: 202 FFGFPGA-----MGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 267 --------GSFGRGGSLGLGG--GGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
                   G+ G  G  G  G  G   G  +  PG+ G+  + G    P F P  E V G
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF-PGSEGVKG 315

Query: 317 DYGHPVYIVQDG 328
           + G P  + +DG
Sbjct: 316 NRGFPGLMGEDG 327



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 66/237 (27%), Positives = 81/237 (34%), Gaps = 60/237 (25%)

Query: 141  SDGTREGLESLQGGVCLTRGMKVLLRVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSLEPG 199
            S+GTR G     G   L   M     +GQ  P G   P  P          GA  S  PG
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 200  KENLPGDPTSNATS-----RGAEGP---LPPPSMPAVAGAAGGLALL-------LLGVAG 244
               LPG P  +        +G  GP     PP +P   G+ G + +        + G AG
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 245  AGGAMCWRRRRAKPSESRHPG-------------PGSFGRGGSLGLGGGGGMGPREAEPG 291
              G       RA P    +PG             PG  GR G++G  G  G    E  PG
Sbjct: 1168 EKGET--GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 292  ELGI---------------ALRGG-GAADPPFCP--HYEKVSGDYGHPVYIVQDGPP 330
              G+                 RG  GA  PP  P  H   + GD G   +    GPP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 195 SLEP-GKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           +L+P G+  +PGDP        +G +G    P +  + G  G LAL   G  G  G    
Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS--GEKGDQGPPGD 600

Query: 252 RRRRAKPSESRHPGP------GSFGRGGSLGLGGGGGMGPREAEP-GELGIALRGGGAAD 304
                 P  +   GP      G  G  G+ G+ G  G  P EA P GEL ++    G   
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPGEAGPRGELSVSTPVPGPPG 659

Query: 305 PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           PP  P +    G  G P  + + G P  P
Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 42/159 (26%), Positives = 51/159 (32%), Gaps = 30/159 (18%)

Query: 197 EPGKENLPGDPTSNATS-----RGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           E G++  PG P S          G  GP  P   P + G  G       GV G  G   +
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGF 101

Query: 252 RRRRAKPSESRHPGP----------GSFGRGGSLGL----------GGGGGMGPREAEPG 291
                 P    + GP          GS G  G  GL          G  G  G + A   
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 292 ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           E  I L   G    P  P  + + G  G P  +   GPP
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPP 200



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 21/148 (14%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG   +PG    N    G++G       P  AG  G     L G+ G  G       + 
Sbjct: 1007 EPGLRGIPGS-MGNMGMPGSKGKRGTLGFPGRAGRPG-----LPGIHGLQGD------KG 1054

Query: 257  KPSESRHPGPGSFGRGGSLGLGGG----GGMGPREAEPGELGIALRGGGAADP--PFCPH 310
            +P  S    PG  G  G  GL G     G MG +   PG LG A   G    P  P  P 
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 311  YEKVSGDYGHPVYIVQDGPP--QSPPNI 336
                 GD G        GPP  + PP +
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141



 Score = 35.4 bits (80), Expect = 0.074
 Identities = 32/106 (30%), Positives = 42/106 (39%), Gaps = 14/106 (13%)

Query: 197  EPGKENLPGDPTSNAT-----SRGAEGPLPPPSMPAVAGAAGGLALLLL-GVAGAGGAMC 250
            +PG +  PG            S G  GP+ P   P V G  G L ++ L G  G  G   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-- 1365

Query: 251  WRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIA 296
                  +P     PGP   G  G+LG  G  G   ++ +PG  G A
Sbjct: 1366 ----PGEPGMQGEPGPP--GPPGNLGPCGPRGKPGKDGKPGTPGPA 1405


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 48/135 (35%), Positives = 55/135 (40%), Gaps = 24/135 (17%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G E  PG P      RGA GP  P   P V G+ G     L G  G  G    +  R 
Sbjct: 352 EKGDEGTPGPPGP----RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 257 KPSESRHPGPGSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVS 315
           +P +     PGS G  GS GL G  G  GP    PG+  I  R G    PP         
Sbjct: 408 RPGKDAMGTPGSPGCAGSPGLPGSPGPPGP----PGD--IVFRKG----PP--------- 448

Query: 316 GDYGHPVYIVQDGPP 330
           GD+G P Y+   G P
Sbjct: 449 GDHGLPGYLGSPGIP 463



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 47/157 (29%), Positives = 58/157 (36%), Gaps = 13/157 (8%)

Query: 185 PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAG 244
           P ER     H  E G   LPG P +   + G +GP   P  P   G  G     + G  G
Sbjct: 758 PGERGNSGEHG-EIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 245 A------GGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALR 298
           A       G    + RR K      PG     R G  G  G  G+   + E G LG   +
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG---Q 872

Query: 299 GGGAADPPFC--PHYEKVSGDYGHPVYIVQDGPPQSP 333
            G   +P     P  + V G  G P  I   GPP +P
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/170 (28%), Positives = 64/170 (37%), Gaps = 41/170 (24%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G A PR P          G   ++ PG+    G P S   S GA GP  PP         
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG-SPGAPGPPGPPGSH------ 1262

Query: 233  GGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPG 291
                  ++G+ G  G+M             HPGP G  G  G +G  G      R   PG
Sbjct: 1263 ------VIGIKGDKGSM------------GHPGPKGPPGTAGDMGPPG------RLGAPG 1298

Query: 292  ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP-----PQSPPNI 336
              G+    G   DP F   +  V G+ G+P ++   GP     P+ PP +
Sbjct: 1299 TPGLP---GPRGDPGF-QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/185 (30%), Positives = 68/185 (36%), Gaps = 28/185 (15%)

Query: 168 GQSPRGG--AVPRKP-VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS 224
           GQ  R G   +P  P V  +P  +    A S E G +  PGDP S   S G  GP  PP 
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGE-LALSGEKGDQGPPGDPGSPG-SPGPAGPAGPPG 617

Query: 225 M-----PAVAGAAGGLALLLLGVAGAGGAMCWRRRRA----------KPSESRHPGP-GS 268
                 P + G  G     + G  G  G    R   +           P    HPGP G 
Sbjct: 618 YGPQGEPGLQGTQG-----VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGP 672

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDG 328
            G  GSLG  G  G+   + EPG  GI     G   P     +    G  G P  + + G
Sbjct: 673 PGIPGSLGKCGDPGLPGPDGEPGIPGIGF--PGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 329 PPQSP 333
            P  P
Sbjct: 731 LPGKP 735



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/138 (32%), Positives = 55/138 (39%), Gaps = 30/138 (21%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG +   G+P       G +G    P MP + G  G     L G AG  G       R 
Sbjct: 956  EPGLKGFAGNP-------GEKGNRGVPGMPGLKGLKG-----LPGPAGPPGP------RG 997

Query: 257  KPSESRHPG-PGSFGRGGSLG-LGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
                + +PG PG  G  GS+G +G  G  G R    G LG      G A  P  P    +
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFP----GRAGRPGLPGIHGL 1049

Query: 315  SGDYGHPVYI--VQDGPP 330
             GD G P Y    + GPP
Sbjct: 1050 QGDKGEPGYSEGTRPGPP 1067



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/192 (26%), Positives = 68/192 (35%), Gaps = 46/192 (23%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPA 227
           G   + GA  ++   E+  + D G   +  PG + LPG P       G  GP+ PP  P 
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGA--PGPQGLPGPP-------GFPGPVGPPGPPG 201

Query: 228 VAGAAGGLALLLLGVAGAGGAMCWR-----RRRAKPSESRHPGP---------------- 266
             G  G      +G  G  G M  R       R     +  PGP                
Sbjct: 202 FFGFPGA-----MGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 267 --------GSFGRGGSLGLGG--GGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
                   G+ G  G  G  G  G   G  +  PG+ G+  + G    P F P  E V G
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF-PGSEGVKG 315

Query: 317 DYGHPVYIVQDG 328
           + G P  + +DG
Sbjct: 316 NRGFPGLMGEDG 327



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 66/237 (27%), Positives = 81/237 (34%), Gaps = 60/237 (25%)

Query: 141  SDGTREGLESLQGGVCLTRGMKVLLRVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSLEPG 199
            S+GTR G     G   L   M     +GQ  P G   P  P          GA  S  PG
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 200  KENLPGDPTSNATS-----RGAEGP---LPPPSMPAVAGAAGGLALL-------LLGVAG 244
               LPG P  +        +G  GP     PP +P   G+ G + +        + G AG
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 245  AGGAMCWRRRRAKPSESRHPG-------------PGSFGRGGSLGLGGGGGMGPREAEPG 291
              G       RA P    +PG             PG  GR G++G  G  G    E  PG
Sbjct: 1168 EKGET--GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 292  ELGI---------------ALRGG-GAADPPFCP--HYEKVSGDYGHPVYIVQDGPP 330
              G+                 RG  GA  PP  P  H   + GD G   +    GPP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 195 SLEP-GKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           +L+P G+  +PGDP        +G +G    P +  + G  G LAL   G  G  G    
Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS--GEKGDQGPPGD 600

Query: 252 RRRRAKPSESRHPGP------GSFGRGGSLGLGGGGGMGPREAEP-GELGIALRGGGAAD 304
                 P  +   GP      G  G  G+ G+ G  G  P EA P GEL ++    G   
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPGEAGPRGELSVSTPVPGPPG 659

Query: 305 PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           PP  P +    G  G P  + + G P  P
Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 40/139 (28%), Positives = 51/139 (36%), Gaps = 22/139 (15%)

Query: 197  EPGKENLPGDPTSNAT-----SRGAEGPLPPPSMPAVAGAAGGLALLLL-GVAGAGGAMC 250
            +PG +  PG            S G  GP+ P   P V G  G L ++ L G  G  G   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-- 1365

Query: 251  WRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--------GA 302
                  +P     PGP   G  G+LG  G  G   ++ +PG  G A   G        G 
Sbjct: 1366 ----PGEPGMQGEPGPP--GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 303  ADPPFCPHYEKVSGDYGHP 321
            A     P  +   GD G P
Sbjct: 1420 AGSDGLPGLKGKRGDSGSP 1438



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 42/159 (26%), Positives = 51/159 (32%), Gaps = 30/159 (18%)

Query: 197 EPGKENLPGDPTSNATS-----RGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           E G++  PG P S          G  GP  P   P + G  G       GV G  G   +
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGF 101

Query: 252 RRRRAKPSESRHPGP----------GSFGRGGSLGL----------GGGGGMGPREAEPG 291
                 P    + GP          GS G  G  GL          G  G  G + A   
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 292 ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           E  I L   G    P  P  + + G  G P  +   GPP
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPP 200



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 21/148 (14%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG   +PG    N    G++G       P  AG  G     L G+ G  G       + 
Sbjct: 1007 EPGLRGIPGS-MGNMGMPGSKGKRGTLGFPGRAGRPG-----LPGIHGLQGD------KG 1054

Query: 257  KPSESRHPGPGSFGRGGSLGLGGG----GGMGPREAEPGELGIALRGGGAADP--PFCPH 310
            +P  S    PG  G  G  GL G     G MG +   PG LG A   G    P  P  P 
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 311  YEKVSGDYGHPVYIVQDGPP--QSPPNI 336
                 GD G        GPP  + PP +
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 48/135 (35%), Positives = 55/135 (40%), Gaps = 24/135 (17%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G E  PG P      RGA GP  P   P V G+ G     L G  G  G    +  R 
Sbjct: 352 EKGDEGTPGPPGP----RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 257 KPSESRHPGPGSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVS 315
           +P +     PGS G  GS GL G  G  GP    PG+  I  R G    PP         
Sbjct: 408 RPGKDAMGTPGSPGCAGSPGLPGSPGPPGP----PGD--IVFRKG----PP--------- 448

Query: 316 GDYGHPVYIVQDGPP 330
           GD+G P Y+   G P
Sbjct: 449 GDHGLPGYLGSPGIP 463



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 47/157 (29%), Positives = 58/157 (36%), Gaps = 13/157 (8%)

Query: 185 PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAG 244
           P ER     H  E G   LPG P +   + G +GP   P  P   G  G     + G  G
Sbjct: 758 PGERGNSGEHG-EIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 245 A------GGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALR 298
           A       G    + RR K      PG     R G  G  G  G+   + E G LG   +
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG---Q 872

Query: 299 GGGAADPPFC--PHYEKVSGDYGHPVYIVQDGPPQSP 333
            G   +P     P  + V G  G P  I   GPP +P
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/170 (28%), Positives = 64/170 (37%), Gaps = 41/170 (24%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G A PR P          G   ++ PG+    G P S   S GA GP  PP         
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG-SPGAPGPPGPPGSH------ 1262

Query: 233  GGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPG 291
                  ++G+ G  G+M             HPGP G  G  G +G  G      R   PG
Sbjct: 1263 ------VIGIKGDKGSM------------GHPGPKGPPGTAGDMGPPG------RLGAPG 1298

Query: 292  ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP-----PQSPPNI 336
              G+    G   DP F   +  V G+ G+P ++   GP     P+ PP +
Sbjct: 1299 TPGLP---GPRGDPGF-QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/185 (30%), Positives = 68/185 (36%), Gaps = 28/185 (15%)

Query: 168 GQSPRGG--AVPRKP-VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS 224
           GQ  R G   +P  P V  +P  +    A S E G +  PGDP S   S G  GP  PP 
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGE-LALSGEKGDQGPPGDPGSPG-SPGPAGPAGPPG 617

Query: 225 M-----PAVAGAAGGLALLLLGVAGAGGAMCWRRRRA----------KPSESRHPGP-GS 268
                 P + G  G     + G  G  G    R   +           P    HPGP G 
Sbjct: 618 YGPQGEPGLQGTQG-----VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGP 672

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDG 328
            G  GSLG  G  G+   + EPG  GI     G   P     +    G  G P  + + G
Sbjct: 673 PGIPGSLGKCGDPGLPGPDGEPGIPGIGF--PGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 329 PPQSP 333
            P  P
Sbjct: 731 LPGKP 735



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/138 (32%), Positives = 55/138 (39%), Gaps = 30/138 (21%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG +   G+P       G +G    P MP + G  G     L G AG  G       R 
Sbjct: 956  EPGLKGFAGNP-------GEKGNRGVPGMPGLKGLKG-----LPGPAGPPGP------RG 997

Query: 257  KPSESRHPG-PGSFGRGGSLG-LGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
                + +PG PG  G  GS+G +G  G  G R    G LG      G A  P  P    +
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFP----GRAGRPGLPGIHGL 1049

Query: 315  SGDYGHPVYI--VQDGPP 330
             GD G P Y    + GPP
Sbjct: 1050 QGDKGEPGYSEGTRPGPP 1067



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/192 (26%), Positives = 68/192 (35%), Gaps = 46/192 (23%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPA 227
           G   + GA  ++   E+  + D G   +  PG + LPG P       G  GP+ PP  P 
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGA--PGPQGLPGPP-------GFPGPVGPPGPPG 201

Query: 228 VAGAAGGLALLLLGVAGAGGAMCWR-----RRRAKPSESRHPGP---------------- 266
             G  G      +G  G  G M  R       R     +  PGP                
Sbjct: 202 FFGFPGA-----MGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 267 --------GSFGRGGSLGLGG--GGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
                   G+ G  G  G  G  G   G  +  PG+ G+  + G    P F P  E V G
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF-PGSEGVKG 315

Query: 317 DYGHPVYIVQDG 328
           + G P  + +DG
Sbjct: 316 NRGFPGLMGEDG 327



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 66/237 (27%), Positives = 81/237 (34%), Gaps = 60/237 (25%)

Query: 141  SDGTREGLESLQGGVCLTRGMKVLLRVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSLEPG 199
            S+GTR G     G   L   M     +GQ  P G   P  P          GA  S  PG
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 200  KENLPGDPTSNATS-----RGAEGP---LPPPSMPAVAGAAGGLALL-------LLGVAG 244
               LPG P  +        +G  GP     PP +P   G+ G + +        + G AG
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 245  AGGAMCWRRRRAKPSESRHPG-------------PGSFGRGGSLGLGGGGGMGPREAEPG 291
              G       RA P    +PG             PG  GR G++G  G  G    E  PG
Sbjct: 1168 EKGET--GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 292  ELGI---------------ALRGG-GAADPPFCP--HYEKVSGDYGHPVYIVQDGPP 330
              G+                 RG  GA  PP  P  H   + GD G   +    GPP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 195 SLEP-GKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           +L+P G+  +PGDP        +G +G    P +  + G  G LAL   G  G  G    
Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS--GEKGDQGPPGD 600

Query: 252 RRRRAKPSESRHPGP------GSFGRGGSLGLGGGGGMGPREAEP-GELGIALRGGGAAD 304
                 P  +   GP      G  G  G+ G+ G  G  P EA P GEL ++    G   
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPGEAGPRGELSVSTPVPGPPG 659

Query: 305 PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           PP  P +    G  G P  + + G P  P
Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 40/139 (28%), Positives = 51/139 (36%), Gaps = 22/139 (15%)

Query: 197  EPGKENLPGDPTSNAT-----SRGAEGPLPPPSMPAVAGAAGGLALLLL-GVAGAGGAMC 250
            +PG +  PG            S G  GP+ P   P V G  G L ++ L G  G  G   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-- 1365

Query: 251  WRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--------GA 302
                  +P     PGP   G  G+LG  G  G   ++ +PG  G A   G        G 
Sbjct: 1366 ----PGEPGMQGEPGPP--GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 303  ADPPFCPHYEKVSGDYGHP 321
            A     P  +   GD G P
Sbjct: 1420 AGSDGLPGLKGKRGDSGSP 1438



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 42/159 (26%), Positives = 51/159 (32%), Gaps = 30/159 (18%)

Query: 197 EPGKENLPGDPTSNATS-----RGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           E G++  PG P S          G  GP  P   P + G  G       GV G  G   +
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGF 101

Query: 252 RRRRAKPSESRHPGP----------GSFGRGGSLGL----------GGGGGMGPREAEPG 291
                 P    + GP          GS G  G  GL          G  G  G + A   
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 292 ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           E  I L   G    P  P  + + G  G P  +   GPP
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPP 200



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 21/148 (14%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG   +PG    N    G++G       P  AG  G     L G+ G  G       + 
Sbjct: 1007 EPGLRGIPGS-MGNMGMPGSKGKRGTLGFPGRAGRPG-----LPGIHGLQGD------KG 1054

Query: 257  KPSESRHPGPGSFGRGGSLGLGGG----GGMGPREAEPGELGIALRGGGAADP--PFCPH 310
            +P  S    PG  G  G  GL G     G MG +   PG LG A   G    P  P  P 
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 311  YEKVSGDYGHPVYIVQDGPP--QSPPNI 336
                 GD G        GPP  + PP +
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 52.0 bits (123), Expect = 8e-07
 Identities = 48/135 (35%), Positives = 55/135 (40%), Gaps = 24/135 (17%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G E  PG P      RGA GP  P   P V G+ G     L G  G  G    +  R 
Sbjct: 352 EKGDEGTPGPPGP----RGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407

Query: 257 KPSESRHPGPGSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVS 315
           +P +     PGS G  GS GL G  G  GP    PG+  I  R G    PP         
Sbjct: 408 RPGKDAMGTPGSPGCAGSPGLPGSPGPPGP----PGD--IVFRKG----PP--------- 448

Query: 316 GDYGHPVYIVQDGPP 330
           GD+G P Y+   G P
Sbjct: 449 GDHGLPGYLGSPGIP 463



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 47/157 (29%), Positives = 58/157 (36%), Gaps = 13/157 (8%)

Query: 185 PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAG 244
           P ER     H  E G   LPG P +   + G +GP   P  P   G  G     + G  G
Sbjct: 758 PGERGNSGEHG-EIGLPGLPGLPGTPG-NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815

Query: 245 A------GGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALR 298
           A       G    + RR K      PG     R G  G  G  G+   + E G LG   +
Sbjct: 816 AQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG---Q 872

Query: 299 GGGAADPPFC--PHYEKVSGDYGHPVYIVQDGPPQSP 333
            G   +P     P  + V G  G P  I   GPP +P
Sbjct: 873 RGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNP 909



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 48/170 (28%), Positives = 64/170 (37%), Gaps = 41/170 (24%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G A PR P          G   ++ PG+    G P S   S GA GP  PP         
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRG-SPGAPGPPGPPGSH------ 1262

Query: 233  GGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPG 291
                  ++G+ G  G+M             HPGP G  G  G +G  G      R   PG
Sbjct: 1263 ------VIGIKGDKGSM------------GHPGPKGPPGTAGDMGPPG------RLGAPG 1298

Query: 292  ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP-----PQSPPNI 336
              G+    G   DP F   +  V G+ G+P ++   GP     P+ PP +
Sbjct: 1299 TPGLP---GPRGDPGF-QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 56/185 (30%), Positives = 68/185 (36%), Gaps = 28/185 (15%)

Query: 168 GQSPRGG--AVPRKP-VSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS 224
           GQ  R G   +P  P V  +P  +    A S E G +  PGDP S   S G  GP  PP 
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKGE-LALSGEKGDQGPPGDPGSPG-SPGPAGPAGPPG 617

Query: 225 M-----PAVAGAAGGLALLLLGVAGAGGAMCWRRRRA----------KPSESRHPGP-GS 268
                 P + G  G     + G  G  G    R   +           P    HPGP G 
Sbjct: 618 YGPQGEPGLQGTQG-----VPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGP 672

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDG 328
            G  GSLG  G  G+   + EPG  GI     G   P     +    G  G P  + + G
Sbjct: 673 PGIPGSLGKCGDPGLPGPDGEPGIPGIGF--PGPPGPKGDQGFPGTKGSLGCPGKMGEPG 730

Query: 329 PPQSP 333
            P  P
Sbjct: 731 LPGKP 735



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 45/138 (32%), Positives = 55/138 (39%), Gaps = 30/138 (21%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG +   G+P       G +G    P MP + G  G     L G AG  G       R 
Sbjct: 956  EPGLKGFAGNP-------GEKGNRGVPGMPGLKGLKG-----LPGPAGPPGP------RG 997

Query: 257  KPSESRHPG-PGSFGRGGSLG-LGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
                + +PG PG  G  GS+G +G  G  G R    G LG      G A  P  P    +
Sbjct: 998  DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFP----GRAGRPGLPGIHGL 1049

Query: 315  SGDYGHPVYI--VQDGPP 330
             GD G P Y    + GPP
Sbjct: 1050 QGDKGEPGYSEGTRPGPP 1067



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 50/192 (26%), Positives = 68/192 (35%), Gaps = 46/192 (23%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPA 227
           G   + GA  ++   E+  + D G   +  PG + LPG P       G  GP+ PP  P 
Sbjct: 151 GLKGQKGAPAKEEDIELDAKGDPGLPGA--PGPQGLPGPP-------GFPGPVGPPGPPG 201

Query: 228 VAGAAGGLALLLLGVAGAGGAMCWR-----RRRAKPSESRHPGP---------------- 266
             G  G      +G  G  G M  R       R     +  PGP                
Sbjct: 202 FFGFPGA-----MGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTD 256

Query: 267 --------GSFGRGGSLGLGG--GGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
                   G+ G  G  G  G  G   G  +  PG+ G+  + G    P F P  E V G
Sbjct: 257 LKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGF-PGSEGVKG 315

Query: 317 DYGHPVYIVQDG 328
           + G P  + +DG
Sbjct: 316 NRGFPGLMGEDG 327



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 66/237 (27%), Positives = 81/237 (34%), Gaps = 60/237 (25%)

Query: 141  SDGTREGLESLQGGVCLTRGMKVLLRVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSLEPG 199
            S+GTR G     G   L   M     +GQ  P G   P  P          GA  S  PG
Sbjct: 1059 SEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGP---------EGAPGS--PG 1107

Query: 200  KENLPGDPTSNATS-----RGAEGP---LPPPSMPAVAGAAGGLALL-------LLGVAG 244
               LPG P  +        +G  GP     PP +P   G+ G + +        + G AG
Sbjct: 1108 SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAG 1167

Query: 245  AGGAMCWRRRRAKPSESRHPG-------------PGSFGRGGSLGLGGGGGMGPREAEPG 291
              G       RA P    +PG             PG  GR G++G  G  G    E  PG
Sbjct: 1168 EKGET--GLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPG 1225

Query: 292  ELGI---------------ALRGG-GAADPPFCP--HYEKVSGDYGHPVYIVQDGPP 330
              G+                 RG  GA  PP  P  H   + GD G   +    GPP
Sbjct: 1226 PPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPP 1282



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/149 (29%), Positives = 60/149 (40%), Gaps = 13/149 (8%)

Query: 195 SLEP-GKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           +L+P G+  +PGDP        +G +G    P +  + G  G LAL   G  G  G    
Sbjct: 543 TLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALS--GEKGDQGPPGD 600

Query: 252 RRRRAKPSESRHPGP------GSFGRGGSLGLGGGGGMGPREAEP-GELGIALRGGGAAD 304
                 P  +   GP      G  G  G+ G+ G  G  P EA P GEL ++    G   
Sbjct: 601 PGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPG-PPGEAGPRGELSVSTPVPGPPG 659

Query: 305 PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           PP  P +    G  G P  + + G P  P
Sbjct: 660 PPGPPGHPGPQGPPGIPGSLGKCGDPGLP 688



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 40/139 (28%), Positives = 51/139 (36%), Gaps = 22/139 (15%)

Query: 197  EPGKENLPGDPTSNAT-----SRGAEGPLPPPSMPAVAGAAGGLALLLL-GVAGAGGAMC 250
            +PG +  PG            S G  GP+ P   P V G  G L ++ L G  G  G   
Sbjct: 1308 DPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT-- 1365

Query: 251  WRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--------GA 302
                  +P     PGP   G  G+LG  G  G   ++ +PG  G A   G        G 
Sbjct: 1366 ----PGEPGMQGEPGPP--GPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGP 1419

Query: 303  ADPPFCPHYEKVSGDYGHP 321
            A     P  +   GD G P
Sbjct: 1420 AGSDGLPGLKGKRGDSGSP 1438



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 42/159 (26%), Positives = 51/159 (32%), Gaps = 30/159 (18%)

Query: 197 EPGKENLPGDPTSNATS-----RGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCW 251
           E G++  PG P S          G  GP  P   P + G  G       GV G  G   +
Sbjct: 47  EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSK-----GVRGISGLPGF 101

Query: 252 RRRRAKPSESRHPGP----------GSFGRGGSLGL----------GGGGGMGPREAEPG 291
                 P    + GP          GS G  G  GL          G  G  G + A   
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAK 161

Query: 292 ELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           E  I L   G    P  P  + + G  G P  +   GPP
Sbjct: 162 EEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPP 200



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 45/148 (30%), Positives = 54/148 (36%), Gaps = 21/148 (14%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            EPG   +PG    N    G++G       P  AG  G     L G+ G  G       + 
Sbjct: 1007 EPGLRGIPGS-MGNMGMPGSKGKRGTLGFPGRAGRPG-----LPGIHGLQGD------KG 1054

Query: 257  KPSESRHPGPGSFGRGGSLGLGGG----GGMGPREAEPGELGIALRGGGAADP--PFCPH 310
            +P  S    PG  G  G  GL G     G MG +   PG LG A   G    P  P  P 
Sbjct: 1055 EPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMG-QPGPPGHLGPAGPEGAPGSPGSPGLPG 1113

Query: 311  YEKVSGDYGHPVYIVQDGPP--QSPPNI 336
                 GD G        GPP  + PP +
Sbjct: 1114 KPGPHGDLGFKGIKGLLGPPGIRGPPGL 1141


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 49/152 (32%), Positives = 59/152 (38%), Gaps = 25/152 (16%)

Query: 198 PGK--ENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
           PGK  E  P  P  +    G  GP  PP  P + G AG   + + G  G  G       R
Sbjct: 114 PGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPGPAG---ISVPGKPGQQGPTGAPGPR 170

Query: 256 AKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPP------ 306
             P E   PG PG  G+ G +G G  G        PGE G+    G  G + PP      
Sbjct: 171 GFPGEKGAPGVPGMNGQKGEMGYGAPG-------RPGERGLPGPQGPTGPSGPPGVGKRG 223

Query: 307 --FCPHYEKVSGDYGHPVYIVQDGP--PQSPP 334
               P    + GD G P  +   GP  PQ PP
Sbjct: 224 ENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPP 255



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 54/173 (31%), Positives = 65/173 (37%), Gaps = 29/173 (16%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAG 230
           P+G   P  P      + +RG+  S   GK   PG P       G +GP   P +P   G
Sbjct: 360 PKGETGPAGPAGYPGAKGERGSPGS--DGKPGYPGKP-------GLDGPKGNPGLPGPKG 410

Query: 231 AAG-GLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGL-------GGGG 281
             G G    L G  G  GA        +      PG PG+ G  G  G+       G  G
Sbjct: 411 DPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPG 470

Query: 282 GMGPREAEPGELGIALRG-GGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             GP    PG  GIA +G  G   PP  P     SG+ G P      GPP  P
Sbjct: 471 SPGP----PGPAGIATKGLNGPTGPPGPPGPRGHSGEPGLP------GPPGPP 513



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 30/101 (29%), Positives = 38/101 (37%), Gaps = 5/101 (4%)

Query: 199 GKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           G+  +PG P    +    G  GP+ PP      G  G   +   G AGA G       + 
Sbjct: 223 GENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKG 282

Query: 257 KPSE---SRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELG 294
            P     +  PGP  FG+ G  GL G  G       PG  G
Sbjct: 283 LPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKG 323



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 41/135 (30%), Positives = 48/135 (35%), Gaps = 24/135 (17%)

Query: 199 GKENLPGDPTSNATSRGAEGPLPPPSM-----------PAVAGAAGGLALLLLGVAGAGG 247
           G++  PG P   A  RG  GP  PP             P + G  G  A+   GV G  G
Sbjct: 57  GEQGTPGPP-GPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPG 115

Query: 248 AMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRG-GGAADPP 306
                    KP E    GP   G  G  GL G  G       PG  GI++ G  G   P 
Sbjct: 116 ---------KPGERGPYGPK--GDVGPAGLPGPRGPPGPPGIPGPAGISVPGKPGQQGPT 164

Query: 307 FCPHYEKVSGDYGHP 321
             P      G+ G P
Sbjct: 165 GAPGPRGFPGEKGAP 179



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 43/157 (27%), Positives = 54/157 (34%), Gaps = 30/157 (19%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSN---------ATSRGAEGPLP 221
           P G +VP KP  + P            PG++  PG P  N         A  R  E  LP
Sbjct: 149 PAGISVPGKPGQQGPTGAPGPRGF---PGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP 205

Query: 222 PPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESR------------HPGPGSF 269
            P  P   G +G   +   G  G  G    +  R  P E                GP   
Sbjct: 206 GPQGPT--GPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGI 263

Query: 270 GRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPP 306
           G+ G+ G  G  G+   +  PG  GIA    G   PP
Sbjct: 264 GKPGAAGAPGQPGIPGTKGLPGAPGIA----GPPGPP 296



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 49/174 (28%), Positives = 61/174 (35%), Gaps = 38/174 (21%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSR--GAEG----PLPP-- 222
           P G   P+ P  E      RG     +PG    PG P    T    GA G    P PP  
Sbjct: 245 PIGPPGPQGPPGE------RGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGF 298

Query: 223 --PSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGG 279
             P +P + G  G       G+ G  GA      + +   +  PG PG  G  G++G  G
Sbjct: 299 GKPGLPGLKGERGPA-----GLPGGPGA------KGEQGPAGLPGKPGLTGPPGNMGPQG 347

Query: 280 GGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             G+      PG  G     G A        Y    G+ G P     DG P  P
Sbjct: 348 PKGIPGSHGLPGPKGETGPAGPAG-------YPGAKGERGSP---GSDGKPGYP 391


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 58/185 (31%), Positives = 71/185 (38%), Gaps = 35/185 (18%)

Query: 169 QSPRG--GAV-PRKPVSEMPMERDRGAAHSLEPGKENLPGD--------PTSNATSRGAE 217
           + PRG  G V P  PV E     +RG      PG + LPG         P  ++  +G++
Sbjct: 503 RGPRGDPGTVGPPGPVGERGAPGNRGF-----PGSDGLPGPKGAQGERGPVGSSGPKGSQ 557

Query: 218 GPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGG 273
           G    P  P + GA G     L G  G  G          P E   PGP    G  G+ G
Sbjct: 558 GDPGRPGEPGLPGARG-----LTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPG 612

Query: 274 SLGLGGGGGMGPREAEPGELGIA----LRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP 329
           S+GL G  G      +PGE G A     RG    D    P     SG  G P    + G 
Sbjct: 613 SMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGP-----SGPVGPPGLAGERG- 666

Query: 330 PQSPP 334
            Q PP
Sbjct: 667 EQGPP 671



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 41/142 (28%), Positives = 50/142 (35%), Gaps = 6/142 (4%)

Query: 198 PGKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCWRRR 254
           PG    PG+P     A   GA GP  P       G  G +    L G  G  G    +  
Sbjct: 374 PGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGP 433

Query: 255 RAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKV 314
              P  S  PG  S G  GS G  G  G      +PG+ G+     G A P   P    +
Sbjct: 434 TGSPGTSGPPG--SAGPPGSPGPQGSTGPQGIRGQPGDPGVP-GFKGEAGPKGEPGPHGI 490

Query: 315 SGDYGHPVYIVQDGPPQSPPNI 336
            G  G P    + GP   P  +
Sbjct: 491 QGPIGPPGEEGKRGPRGDPGTV 512



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 19/135 (14%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATS-----RGAEGPLPPP 223
           Q P G    +    E   + D G+     PG + L G P  +  +     +G  G   PP
Sbjct: 851 QGPDGQPGVKGEPGEPGQKGDAGS-----PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPP 905

Query: 224 SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG----PGSFGRGGSLGLGG 279
                 G+AG +     G  G  GA        +P +   PG    PGS GR G  G  G
Sbjct: 906 GATGFPGSAGRV-----GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAG 960

Query: 280 GGGMGPREAEPGELG 294
             G    + +PGE G
Sbjct: 961 PPGGPGDKGDPGEDG 975



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 38/129 (29%), Positives = 49/129 (37%), Gaps = 16/129 (12%)

Query: 174  GAVPRKPVSEMPMERDRGAAHSLEPGKENLPGD--PTSNATSRGAEGPLPPPSM------ 225
            G   ++ +  MP +R       L PG    PG   PT     +G  GP+ PP        
Sbjct: 987  GTTGQRGIVGMPGQRGERGMPGL-PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGE 1045

Query: 226  PAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGP 285
            P   G AG       G  G  GA+  R  R  P  +  PG  S G  G+ G  G  G   
Sbjct: 1046 PGPEGPAGND-----GTPGRDGAVGERGDRGDPGPAGLPG--SQGAPGTPGPVGAPGDAG 1098

Query: 286  REAEPGELG 294
            +  +PG  G
Sbjct: 1099 QRGDPGSRG 1107



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 46/166 (27%), Positives = 60/166 (36%), Gaps = 15/166 (9%)

Query: 169 QSPRGGAVPR-KPVSEMPMERDRGAAHSLEPGKENLPGDPTS---NATSRGAEGPLPPPS 224
           Q PRG   P+ +P    P   D       +PG    PG P+    +  SR     +    
Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLD 199

Query: 225 MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA------KPSESRHPGP----GSFGRGGS 274
             +  G+  GL    +G  G  G    + ++        P E   PGP    GS G  G 
Sbjct: 200 EKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGP 259

Query: 275 LGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGH 320
            G  G  G   R   PGE+G A    GA   P  P    + G  GH
Sbjct: 260 PGKPGEDGEPGRNGNPGEVGFA-GSPGARGFPGAPGLPGLKGHRGH 304



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 47/153 (30%), Positives = 57/153 (37%), Gaps = 25/153 (16%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCWRRRR 255
           +PG + +PGDP       GA GPL P       G  G   +  L G  G  G       +
Sbjct: 691 KPGDQGVPGDP-------GAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743

Query: 256 AKPSESRHPG----PGSFGRGGSLGLGG-------GGGMGPREAEPGELGIALRGG--GA 302
             P  S  PG    PG  G  G  G+ G        GG+G + AE    G A   G  G 
Sbjct: 744 GSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAE----GTAGNDGARGL 799

Query: 303 ADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPPN 335
             P   P     +G+ G P      GPP S  N
Sbjct: 800 PGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGN 832



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 36/111 (32%), Positives = 42/111 (37%), Gaps = 18/111 (16%)

Query: 198 PGKENLPGD-----PTSNATSRGAEGP--------LP-PPSMPAVAGAAGGLALLLLGVA 243
           PGK+   G      P   A  RG +GP        LP PP  P   G  G   +   G  
Sbjct: 644 PGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVP--GDP 701

Query: 244 GAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELG 294
           GA G +  R  R  P E   PG    G  G  G+ GG G    +  PG  G
Sbjct: 702 GAVGPLGPRGERGNPGERGEPG--ITGLPGEKGMAGGHGPDGPKGSPGPSG 750



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 45/158 (28%), Positives = 54/158 (34%), Gaps = 22/158 (13%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAG 230
           P G   P  P  E      RG     +PG    PG P     + G  G      +P   G
Sbjct: 487 PHGIQGPIGPPGEEGKRGPRG-----DPGTVGPPG-PVGERGAPGNRGFPGSDGLPGPKG 540

Query: 231 AAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-------PGSFGRGGSLGLGGGGGM 283
           A G       G  G+ G    +    +P E   PG       PG  G  G LG  G  G 
Sbjct: 541 AQGER-----GPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595

Query: 284 GPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHP 321
             R   PG +GI  + G        P  +  SGD G P
Sbjct: 596 DGRPGPPGSIGIRGQPGSMG----LPGPKGSSGDPGKP 629



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 15/109 (13%)

Query: 189 DRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGA 248
           DRG     E G E   G    N  +RG  GPL PP      G  G       G+ G  G+
Sbjct: 778 DRGGIG--EKGAEGTAG----NDGARGLPGPLGPPGPAGPTGEKGEPG--PRGLVGPPGS 829

Query: 249 MCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIA 296
                 R  P      GP G+ G  G  G  G  G+     EPG+ G A
Sbjct: 830 ------RGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDA 872



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 32/108 (29%), Positives = 37/108 (34%), Gaps = 12/108 (11%)

Query: 198 PGKENLPGDP-----TSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCW 251
           PG    PG P       +   +G EGP      P   G AG    +  +G  G  G M  
Sbjct: 284 PGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRG-MPG 342

Query: 252 RRRRAKPS-----ESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELG 294
            R R  P         H  PG  G  G LG+ G  G        GE G
Sbjct: 343 ERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 31/109 (28%), Positives = 42/109 (38%), Gaps = 17/109 (15%)

Query: 198 PGKENLPGDPTSNAT--SRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
           PG    PG P +  T  + GA+GP   P      G+AG       G  G  G+   +  R
Sbjct: 410 PGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPP-----GSPGPQGSTGPQGIR 464

Query: 256 AKPSESRHPG----------PGSFGRGGSLGLGGGGGMGPREAEPGELG 294
            +P +   PG          PG  G  G +G  G  G      +PG +G
Sbjct: 465 GQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVG 513



 Score = 32.0 bits (71), Expect = 0.82
 Identities = 34/129 (26%), Positives = 40/129 (31%), Gaps = 34/129 (26%)

Query: 172  RGGAVPRKPVSEMPMERDRG----AAHSLEPGKENLPGDPTSNAT--SRGAEGPLPPPSM 225
            RG   P+ P  +     DRG      H    G + LPG P  N    S G  GP  P   
Sbjct: 1118 RGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGP 1177

Query: 226  PAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGP 285
            P   G +G                            +   PG  G  G  G+ G  G   
Sbjct: 1178 PGPVGPSG----------------------------KEGNPGPLGPIGPPGVRGSVGEAG 1209

Query: 286  REAEPGELG 294
             E  PGE G
Sbjct: 1210 PEGPPGEPG 1218



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 31/112 (27%), Positives = 40/112 (35%), Gaps = 11/112 (9%)

Query: 197  EPGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRR 254
            +PG++  PG   P   A + G  G +  P      G  G     L G AG  G +     
Sbjct: 970  DPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPG-----LPGPAGTPGKV---GP 1021

Query: 255  RAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADP 305
                 +   PGP G  G  G +G  G  G    +  PG  G     G   DP
Sbjct: 1022 TGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDP 1073


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 48/163 (29%), Positives = 58/163 (35%), Gaps = 14/163 (8%)

Query: 171 PRGGAVPRKPVSEMPMERDRG-AAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVA 229
           P+G   P+ P  E     DRG       PG     G+P +     G  GP  PP  P   
Sbjct: 118 PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP----GNPGPPGPPGPPGPP 173

Query: 230 GAAGGLALLLLG--VAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPRE 287
           G  G  A  + G     AGGA     +           PG  G  G  G  G  G     
Sbjct: 174 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG----- 228

Query: 288 AEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
            EPGE G++    G   PP  P      G+ G P    + GPP
Sbjct: 229 -EPGEPGVS-GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 269



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 49/173 (28%), Positives = 63/173 (36%), Gaps = 28/173 (16%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS--- 224
           G++   G V  +     P ER    A  L+ G   LPG P ++   +GA GP  PP    
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQ-GPRGLPGTPGTDGP-KGASGPAGPPGAQG 744

Query: 225 ------MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSES---------RHPGP-GS 268
                 MP   GAAG     + G  G  G +  +     P +            PGP G+
Sbjct: 745 PPGLQGMPGERGAAG-----IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVSGDYG 319
            G  G +G  G  G       PGE G     G  G A PP         G+ G
Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 852



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 42/135 (31%), Positives = 49/135 (36%), Gaps = 12/135 (8%)

Query: 177 PRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLA 236
           PR P        D G A   +PGK    G P      +GA G    P +P V G  G   
Sbjct: 241 PRGPPGPPGKPGDDGEAG--KPGKAGERGPPGP----QGARGFPGTPGLPGVKGHRGYPG 294

Query: 237 LLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLGLGGGGGMGPREAEPGE 292
           L   G  G  GA   +     P E+  PGP    G  G  G  G  G  G    + +PG 
Sbjct: 295 LD--GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP 352

Query: 293 LGIALRGGGAADPPF 307
            G     G A  P F
Sbjct: 353 AGPPGPVGPAGGPGF 367



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 16/123 (13%)

Query: 183 EMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGV 242
           E   + D GA     P     P  PT     +GA G   PP      GAAG      +G 
Sbjct: 853 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG-----RVGP 907

Query: 243 AGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGA 302
            G+ G          P     PGP   G+ G  G  G  G   R  EPG  G A   G  
Sbjct: 908 PGSNG---------NPGPPGPPGPS--GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 956

Query: 303 ADP 305
            +P
Sbjct: 957 GEP 959



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/152 (28%), Positives = 54/152 (35%), Gaps = 35/152 (23%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG +   G P  N    G+ GP+ P  +P   G  G         AGA GA   R    +
Sbjct: 305 PGVKGESGSPGEN----GSPGPMGPRGLPGERGRTGP--------AGAAGA---RGNDGQ 349

Query: 258 PSESRHPGP-------------GSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAA 303
           P  +  PGP             G+ G  G  G  G  G  GPR  EPG  G     G + 
Sbjct: 350 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR-GEPGTPGSPGPAGASG 408

Query: 304 DP-----PFCPHYEKVSGDYGHPVYIVQDGPP 330
           +P     P         G  G P +    GPP
Sbjct: 409 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 440



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 40/130 (30%), Positives = 49/130 (37%), Gaps = 13/130 (10%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCWRRRR 255
            EPGK+  PG     +  RG  GP+ PP +   AG  G        G  G  GA   +  R
Sbjct: 1003 EPGKQGAPGA----SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 1058

Query: 256  AKPSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHY 311
             +      PG    PGS G  G  G  G  G    +   G  G A  G      P  P  
Sbjct: 1059 GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA--GARGIQGPQGPRG 1116

Query: 312  EKVSGDYGHP 321
            +K  G+ G P
Sbjct: 1117 DK--GEAGEP 1124



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 49/190 (25%), Positives = 58/190 (30%), Gaps = 32/190 (16%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEP----------GKENLPGD-----------PTS 209
           P G    + P     M  +RGAA    P          G E  PG            P  
Sbjct: 736 PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 795

Query: 210 NATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG---- 265
            A + G +G + PP     AGA G       G  G  G          P     PG    
Sbjct: 796 PAGANGEKGEVGPPGPAGSAGARGA-----PGERGETGPPGPAGFAGPPGADGQPGAKGE 850

Query: 266 PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVSGDYGHPVY 323
            G  G+ G  G  G  G        G  G+    G  GA  PP    +   +G  G P  
Sbjct: 851 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 910

Query: 324 IVQDGPPQSP 333
               GPP  P
Sbjct: 911 NGNPGPPGPP 920



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 13/133 (9%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGA-AHSLEPGKENLPGDP--TSNATSRGAEGPLPPPSM 225
            Q P+G   PR    E     +RG   H    G + LPG P  + +  + G  GP  P   
Sbjct: 1109 QGPQG---PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1165

Query: 226  PAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLG----GG 280
            P   G +G       G+ G  G    R R  +   +  PG PG  G  G  G G      
Sbjct: 1166 PGPVGPSGKDGAN--GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1223

Query: 281  GGMGPREAEPGEL 293
             G+GPRE  P  L
Sbjct: 1224 AGLGPREKGPDPL 1236



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 51/181 (28%), Positives = 60/181 (33%), Gaps = 46/181 (25%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPG-----------------DPTSNA 211
           Q PRG   P  P S  P      A  S  PG + +PG                  P    
Sbjct: 389 QGPRGE--PGTPGSPGP------AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 440

Query: 212 TSRGAEGPLPPPSM---PAVAGAAGGLALL-LLGVAGAGGAMCWRRRRAKPSESRHPG-- 265
             +GA GPL P      P +AG  G        G AG  GA        K      PG  
Sbjct: 441 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV 500

Query: 266 -----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGH 320
                PG  G  G+ G  G  G+   +  PGE G      G A P      +  +GD G 
Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG----PSGLAGP------KGANGDPGR 550

Query: 321 P 321
           P
Sbjct: 551 P 551



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 29/143 (20%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG+   PG    N    G +G   P   P   G +G     L G  GA G         +
Sbjct: 506 PGERGAPG----NRGFPGQDGLAGPKGAPGERGPSG-----LAGPKGANGDP------GR 550

Query: 258 PSESRHPG-------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPH 310
           P E   PG       PG  G  G +G  G  G   R   PG         GA   P    
Sbjct: 551 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-------QGARGQPGVMG 603

Query: 311 YEKVSGDYGHPVYIVQDGPPQSP 333
           +    G  G P    + G P +P
Sbjct: 604 FPGPKGANGEPGKAGEKGLPGAP 626



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/149 (28%), Positives = 49/149 (32%), Gaps = 22/149 (14%)

Query: 197 EPGK---ENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRR 253
           EPGK   + LPG P       G +G       P  AG AG       G  G  G      
Sbjct: 613 EPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQ--GAPGPSGFQGLPG 669

Query: 254 RRAKPSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCP 309
               P E   PG    PG  G  G +G  G  G       PG  G+     G    P  P
Sbjct: 670 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ----GPRGLPGTP 725

Query: 310 HYEKVSGDYGHPVYIVQDGPP--QSPPNI 336
             +   G  G        GPP  Q PP +
Sbjct: 726 GTDGPKGASG------PAGPPGAQGPPGL 748



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 47/192 (24%), Positives = 56/192 (29%), Gaps = 41/192 (21%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPG-----DPTSNATSRGAEGPLPPP 223
            Q P G   P+ P      +  RGA     PG    PG      P  +  + G  GP  P 
Sbjct: 866  QGPSGAPGPQGPTGVTGPKGARGAQGP--PGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 923

Query: 224  SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG------------------ 265
                  GA G       G  G  G    +     P E   PG                  
Sbjct: 924  GKDGPKGARGDS-----GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 978

Query: 266  -------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDY 318
                   PG  G  G  GL G  G   ++  PG  G      G   P   P     +G+ 
Sbjct: 979  QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG----DRGPPGPVGPPGLTGPAGEP 1034

Query: 319  GHPVYIVQDGPP 330
            G       DGPP
Sbjct: 1035 GREGSPGADGPP 1046



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 36/125 (28%), Positives = 44/125 (35%), Gaps = 14/125 (11%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG++  PG P     +RG  G +  P      G  G       G  G  GA   R    K
Sbjct: 581 PGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKA-----GEKGLPGAPGLRGLPGK 634

Query: 258 PSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
             E+   GP G  G  G  G  G  G    +  PG  G    GG   D       + V G
Sbjct: 635 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD-------QGVPG 687

Query: 317 DYGHP 321
           + G P
Sbjct: 688 EAGAP 692



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 45/169 (26%), Positives = 55/169 (32%), Gaps = 32/169 (18%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAG 230
            P G   P  P  +   + DRG     E G +  P  P+  A +RG +GP  P      AG
Sbjct: 1072 PPGSPGPAGPTGK---QGDRG-----EAGAQG-PMGPSGPAGARGIQGPQGPRGDKGEAG 1122

Query: 231  AAGGLALL-LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAE 289
              G   L    G  G  G                  PG  G  G  G  G  G       
Sbjct: 1123 EPGERGLKGHRGFTGLQGL-----------------PGPPGPSGDQGASGPAGPSGPRGP 1165

Query: 290  PGELGIALRGG-----GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            PG +G + + G     G   PP        +G  G P      GPP  P
Sbjct: 1166 PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 48/163 (29%), Positives = 58/163 (35%), Gaps = 14/163 (8%)

Query: 171 PRGGAVPRKPVSEMPMERDRG-AAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVA 229
           P+G   P+ P  E     DRG       PG     G+P +     G  GP  PP  P   
Sbjct: 49  PKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP----GNPGPPGPPGPPGPP 104

Query: 230 GAAGGLALLLLG--VAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPRE 287
           G  G  A  + G     AGGA     +           PG  G  G  G  G  G     
Sbjct: 105 GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG----- 159

Query: 288 AEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
            EPGE G++    G   PP  P      G+ G P    + GPP
Sbjct: 160 -EPGEPGVS-GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPP 200



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 49/173 (28%), Positives = 63/173 (36%), Gaps = 28/173 (16%)

Query: 168 GQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPS--- 224
           G++   G V  +     P ER    A  L+ G   LPG P ++   +GA GP  PP    
Sbjct: 618 GEAGAPGLVGPRGERGFPGERGSPGAQGLQ-GPRGLPGTPGTDGP-KGASGPAGPPGAQG 675

Query: 225 ------MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSES---------RHPGP-GS 268
                 MP   GAAG     + G  G  G +  +     P +            PGP G+
Sbjct: 676 PPGLQGMPGERGAAG-----IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 269 FGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVSGDYG 319
            G  G +G  G  G       PGE G     G  G A PP         G+ G
Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQG 783



 Score = 42.0 bits (97), Expect = 8e-04
 Identities = 42/135 (31%), Positives = 49/135 (36%), Gaps = 12/135 (8%)

Query: 177 PRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLA 236
           PR P        D G A   +PGK    G P      +GA G    P +P V G  G   
Sbjct: 172 PRGPPGPPGKPGDDGEAG--KPGKAGERGPPGP----QGARGFPGTPGLPGVKGHRGYPG 225

Query: 237 LLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLGLGGGGGMGPREAEPGE 292
           L   G  G  GA   +     P E+  PGP    G  G  G  G  G  G    + +PG 
Sbjct: 226 LD--GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP 283

Query: 293 LGIALRGGGAADPPF 307
            G     G A  P F
Sbjct: 284 AGPPGPVGPAGGPGF 298



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 37/123 (30%), Positives = 43/123 (34%), Gaps = 16/123 (13%)

Query: 183 EMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGV 242
           E   + D GA     P     P  PT     +GA G   PP      GAAG      +G 
Sbjct: 784 EAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG-----RVGP 838

Query: 243 AGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGA 302
            G+ G          P     PGP   G+ G  G  G  G   R  EPG  G A   G  
Sbjct: 839 PGSNG---------NPGPPGPPGPS--GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK 887

Query: 303 ADP 305
            +P
Sbjct: 888 GEP 890



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 44/152 (28%), Positives = 54/152 (35%), Gaps = 35/152 (23%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG +   G P  N    G+ GP+ P  +P   G  G         AGA GA   R    +
Sbjct: 236 PGVKGESGSPGEN----GSPGPMGPRGLPGERGRTGP--------AGAAGA---RGNDGQ 280

Query: 258 PSESRHPGP-------------GSFGRGGSLGL-GGGGGMGPREAEPGELGIALRGGGAA 303
           P  +  PGP             G+ G  G  G  G  G  GPR  EPG  G     G + 
Sbjct: 281 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR-GEPGTPGSPGPAGASG 339

Query: 304 DP-----PFCPHYEKVSGDYGHPVYIVQDGPP 330
           +P     P         G  G P +    GPP
Sbjct: 340 NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 371



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 40/130 (30%), Positives = 49/130 (37%), Gaps = 13/130 (10%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCWRRRR 255
            EPGK+  PG     +  RG  GP+ PP +   AG  G        G  G  GA   +  R
Sbjct: 934  EPGKQGAPGA----SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDR 989

Query: 256  AKPSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHY 311
             +      PG    PGS G  G  G  G  G    +   G  G A  G      P  P  
Sbjct: 990  GETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA--GARGIQGPQGPRG 1047

Query: 312  EKVSGDYGHP 321
            +K  G+ G P
Sbjct: 1048 DK--GEAGEP 1055



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 49/190 (25%), Positives = 58/190 (30%), Gaps = 32/190 (16%)

Query: 171 PRGGAVPRKPVSEMPMERDRGAAHSLEP----------GKENLPGD-----------PTS 209
           P G    + P     M  +RGAA    P          G E  PG            P  
Sbjct: 667 PAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPG 726

Query: 210 NATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG---- 265
            A + G +G + PP     AGA G       G  G  G          P     PG    
Sbjct: 727 PAGANGEKGEVGPPGPAGSAGARGA-----PGERGETGPPGPAGFAGPPGADGQPGAKGE 781

Query: 266 PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVSGDYGHPVY 323
            G  G+ G  G  G  G        G  G+    G  GA  PP    +   +G  G P  
Sbjct: 782 QGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGS 841

Query: 324 IVQDGPPQSP 333
               GPP  P
Sbjct: 842 NGNPGPPGPP 851



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 41/133 (30%), Positives = 52/133 (39%), Gaps = 13/133 (9%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGA-AHSLEPGKENLPGDP--TSNATSRGAEGPLPPPSM 225
            Q P+G   PR    E     +RG   H    G + LPG P  + +  + G  GP  P   
Sbjct: 1040 QGPQG---PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1096

Query: 226  PAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLG----GG 280
            P   G +G       G+ G  G    R R  +   +  PG PG  G  G  G G      
Sbjct: 1097 PGPVGPSGKDGAN--GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAF 1154

Query: 281  GGMGPREAEPGEL 293
             G+GPRE  P  L
Sbjct: 1155 AGLGPREKGPDPL 1167



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 51/181 (28%), Positives = 60/181 (33%), Gaps = 46/181 (25%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPG-----------------DPTSNA 211
           Q PRG   P  P S  P      A  S  PG + +PG                  P    
Sbjct: 320 QGPRGE--PGTPGSPGP------AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPP 371

Query: 212 TSRGAEGPLPPPSM---PAVAGAAGGLALL-LLGVAGAGGAMCWRRRRAKPSESRHPG-- 265
             +GA GPL P      P +AG  G        G AG  GA        K      PG  
Sbjct: 372 GPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGV 431

Query: 266 -----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGH 320
                PG  G  G+ G  G  G+   +  PGE G      G A P      +  +GD G 
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERG----PSGLAGP------KGANGDPGR 481

Query: 321 P 321
           P
Sbjct: 482 P 482



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 39/143 (27%), Positives = 47/143 (32%), Gaps = 29/143 (20%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG+   PG    N    G +G   P   P   G +G     L G  GA G         +
Sbjct: 437 PGERGAPG----NRGFPGQDGLAGPKGAPGERGPSG-----LAGPKGANGDP------GR 481

Query: 258 PSESRHPG-------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPH 310
           P E   PG       PG  G  G +G  G  G   R   PG         GA   P    
Sbjct: 482 PGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-------QGARGQPGVMG 534

Query: 311 YEKVSGDYGHPVYIVQDGPPQSP 333
           +    G  G P    + G P +P
Sbjct: 535 FPGPKGANGEPGKAGEKGLPGAP 557



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/149 (28%), Positives = 49/149 (32%), Gaps = 22/149 (14%)

Query: 197 EPGK---ENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRR 253
           EPGK   + LPG P       G +G       P  AG AG       G  G  G      
Sbjct: 544 EPGKAGEKGLPGAPGLRGLP-GKDGETGAAGPPGPAGPAGERGEQ--GAPGPSGFQGLPG 600

Query: 254 RRAKPSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCP 309
               P E   PG    PG  G  G +G  G  G       PG  G+     G    P  P
Sbjct: 601 PPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ----GPRGLPGTP 656

Query: 310 HYEKVSGDYGHPVYIVQDGPP--QSPPNI 336
             +   G  G        GPP  Q PP +
Sbjct: 657 GTDGPKGASG------PAGPPGAQGPPGL 679



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 47/192 (24%), Positives = 56/192 (29%), Gaps = 41/192 (21%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPG-----DPTSNATSRGAEGPLPPP 223
           Q P G   P+ P      +  RGA     PG    PG      P  +  + G  GP  P 
Sbjct: 797 QGPSGAPGPQGPTGVTGPKGARGAQGP--PGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854

Query: 224 SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG------------------ 265
                 GA G       G  G  G    +     P E   PG                  
Sbjct: 855 GKDGPKGARGDS-----GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAG 909

Query: 266 -------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDY 318
                  PG  G  G  GL G  G   ++  PG  G      G   P   P     +G+ 
Sbjct: 910 QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASG----DRGPPGPVGPPGLTGPAGEP 965

Query: 319 GHPVYIVQDGPP 330
           G       DGPP
Sbjct: 966 GREGSPGADGPP 977



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 36/125 (28%), Positives = 44/125 (35%), Gaps = 14/125 (11%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG++  PG P     +RG  G +  P      G  G       G  G  GA   R    K
Sbjct: 512 PGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKA-----GEKGLPGAPGLRGLPGK 565

Query: 258 PSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
             E+   GP G  G  G  G  G  G    +  PG  G    GG   D       + V G
Sbjct: 566 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD-------QGVPG 618

Query: 317 DYGHP 321
           + G P
Sbjct: 619 EAGAP 623



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 45/169 (26%), Positives = 55/169 (32%), Gaps = 32/169 (18%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAG 230
            P G   P  P  +   + DRG     E G +  P  P+  A +RG +GP  P      AG
Sbjct: 1003 PPGSPGPAGPTGK---QGDRG-----EAGAQG-PMGPSGPAGARGIQGPQGPRGDKGEAG 1053

Query: 231  AAGGLALL-LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAE 289
              G   L    G  G  G                  PG  G  G  G  G  G       
Sbjct: 1054 EPGERGLKGHRGFTGLQGL-----------------PGPPGPSGDQGASGPAGPSGPRGP 1096

Query: 290  PGELGIALRGG-----GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            PG +G + + G     G   PP        +G  G P      GPP  P
Sbjct: 1097 PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 49/149 (32%), Positives = 64/149 (42%), Gaps = 27/149 (18%)

Query: 197  EPGKENLPGDPTS-------NATSR-GAEGPLPPPSMPAVAGAAGGLALL----LLGVAG 244
            +PG + L G P S        AT + G  GP+ PP +P + G AG         L+G+ G
Sbjct: 1275 KPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIG 1334

Query: 245  AGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIA-LRGGGA 302
              G       + +  +   PGP GS G+ G +G+ G  G       PG  G A  +G   
Sbjct: 1335 PPG------EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1388

Query: 303  ADPPFCPHYEK-VSGDYGHPVYIVQDGPP 330
            A  P  P  EK V G  GHP      GPP
Sbjct: 1389 ATGPGGPKGEKGVQGPPGHP------GPP 1411



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/160 (29%), Positives = 56/160 (35%), Gaps = 29/160 (18%)

Query: 198 PGKENLPGDPTSNATS--RGAEGPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCW 251
           PGK+ LPG P        +G  GP  PP +    GAAG    +      G  G  G    
Sbjct: 811 PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 870

Query: 252 RRRRAKPSESRHPGP-GSFGRGGSLGLGG----------GGGMGPREAE----------- 289
                K      PGP G+ G+ G  GL G           GG G +  E           
Sbjct: 871 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930

Query: 290 PGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP 329
           PGE G A   GG   PP  P  +   G  G      + GP
Sbjct: 931 PGERGAA-GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-GLALLLLGVAGAGGAMCWRRRRAK 257
            G + LPG P+      G  GP+ PP  P   G AG   A    G  G  G +     + +
Sbjct: 1070 GLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 258  PSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADP 305
            P ES  PG    PG  G  G  G  G  G       PG  G     G   +P
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/161 (27%), Positives = 57/161 (35%), Gaps = 16/161 (9%)

Query: 189  DRGAAHSLEPGKENLPGDPTSNATSRGAEGP---------LPPPSMPAVAGAAGGLALL- 238
            ++G    + P     P  P   A   GA+GP         L PP      G +G   +  
Sbjct: 1080 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1139

Query: 239  LLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIAL 297
              GV G  G    +    +P E   PGP G  G  G  G  G  G       PGE G   
Sbjct: 1140 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1199

Query: 298  RGGGAAD-----PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            + G   D      P  P     +G+ G P  + + GP  SP
Sbjct: 1200 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1240



 Score = 35.4 bits (80), Expect = 0.074
 Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 37/146 (25%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G   LPG+    +  RG  GP  PP +P   G  G     + G  G  G++       
Sbjct: 510 EIGPRGLPGE----SGPRGLLGPKGPPGIPGPPGVRG-----MDGPQGPKGSL------- 553

Query: 257 KPSESRHPG-PGSFGRGGSLGL-GGGGGMGPR-----EAEPGELGIALRGGGAADPPFCP 309
                  PG PG  G  G+ GL G  G +GP      + +PG  G+     G+  PP  P
Sbjct: 554 --GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP----GSDGPPGHP 607

Query: 310 HYEKVSGDYGHPVYIVQDGP--PQSP 333
             E   G  G+       GP  PQ P
Sbjct: 608 GKEGPPGTKGN------QGPSGPQGP 627



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 16/146 (10%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     +PG++   G+   +    G  GP+ P   P  
Sbjct: 979  QGPVGLPGPAGPPGVAGEDGDKGEVG--DPGQKGTKGNKGEHGPP-GPPGPIGPVGQPGA 1035

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLG-LGGGGGM 283
            AGA G       G  G  G    +        +  PGP    G  G  G  G  G  G M
Sbjct: 1036 AGADGE-----PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1090

Query: 284  GPREAEPGELGIALRGGGAADPPFCP 309
            GP    PG  G A  G   AD P  P
Sbjct: 1091 GP-PGPPGPRGPA--GPNGADGPQGP 1113



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 50/190 (26%), Positives = 67/190 (35%), Gaps = 29/190 (15%)

Query: 168  GQSPRGGAVPRKPVSEMPMERDRGAAHSLEP----------------GKENLPGD--PTS 209
            G   +G   P  P        +RGAA S  P                G++ +PG+  P  
Sbjct: 912  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 971

Query: 210  NATSRGAEGP--LPPPS-MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP 266
                 G +GP  LP P+  P VAG  G       G  G  G    +  + +      PGP
Sbjct: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGD-----KGEVGDPGQKGTKGNKGEHGPPGPPGP 1026

Query: 267  -GSFGRGGSLGLGG-GGGMGPREAEPGELGIALRG-GGAADPPFCPHYEKVSGDYGHPVY 323
             G  G+ G+ G  G  G  GP+     +     RG  G   P         SG+ G    
Sbjct: 1027 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD 1086

Query: 324  IVQDGPPQSP 333
            +   GPP  P
Sbjct: 1087 VGPMGPPGPP 1096



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 35/127 (27%), Positives = 46/127 (36%), Gaps = 10/127 (7%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSR--GAEGPLPPPSMPAV 228
            PRG A P    ++ P     G  +   PG++  PG+  S       G +GP         
Sbjct: 1098 PRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1155

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPRE 287
            +G  G       G  G  G       +  P     PG PG  G GG  G  G  G    +
Sbjct: 1156 SGQPGEP-----GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1210

Query: 288  AEPGELG 294
             EPG+ G
Sbjct: 1211 GEPGQPG 1217



 Score = 32.0 bits (71), Expect = 0.82
 Identities = 55/200 (27%), Positives = 67/200 (33%), Gaps = 42/200 (21%)

Query: 159 RGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGD--PTSNATSRGA 216
           +G   +L  G    G   P  P   +     +G      PG    PG+  P   A   G+
Sbjct: 299 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG-----NPGPVGDPGERGPPGRAGLPGS 353

Query: 217 EGPLPPPS----MPAVAGAAGG----------------LALLLLGVAGAGGAMCWRRRRA 256
           +G   PP     +P   G+ GG                L    L + G  G M +  R  
Sbjct: 354 DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR-- 411

Query: 257 KPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEK 313
            P     PG PG  G  G LG  G  G       PG+ G   R G  GA   P  P    
Sbjct: 412 -PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP---G 467

Query: 314 VSGDYGHPVYIVQDGPPQSP 333
           V GD G       DG P  P
Sbjct: 468 VKGDRGF------DGLPGLP 481


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 49/149 (32%), Positives = 64/149 (42%), Gaps = 27/149 (18%)

Query: 197  EPGKENLPGDPTS-------NATSR-GAEGPLPPPSMPAVAGAAGGLALL----LLGVAG 244
            +PG + L G P S        AT + G  GP+ PP +P + G AG         L+G+ G
Sbjct: 1254 KPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIG 1313

Query: 245  AGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIA-LRGGGA 302
              G       + +  +   PGP GS G+ G +G+ G  G       PG  G A  +G   
Sbjct: 1314 PPG------EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1367

Query: 303  ADPPFCPHYEK-VSGDYGHPVYIVQDGPP 330
            A  P  P  EK V G  GHP      GPP
Sbjct: 1368 ATGPGGPKGEKGVQGPPGHP------GPP 1390



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/160 (29%), Positives = 56/160 (35%), Gaps = 29/160 (18%)

Query: 198 PGKENLPGDPTSNATS--RGAEGPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCW 251
           PGK+ LPG P        +G  GP  PP +    GAAG    +      G  G  G    
Sbjct: 790 PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 849

Query: 252 RRRRAKPSESRHPGP-GSFGRGGSLGLGG----------GGGMGPREAE----------- 289
                K      PGP G+ G+ G  GL G           GG G +  E           
Sbjct: 850 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909

Query: 290 PGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP 329
           PGE G A   GG   PP  P  +   G  G      + GP
Sbjct: 910 PGERGAA-GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-GLALLLLGVAGAGGAMCWRRRRAK 257
            G + LPG P+      G  GP+ PP  P   G AG   A    G  G  G +     + +
Sbjct: 1049 GLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 258  PSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADP 305
            P ES  PG    PG  G  G  G  G  G       PG  G     G   +P
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/161 (27%), Positives = 57/161 (35%), Gaps = 16/161 (9%)

Query: 189  DRGAAHSLEPGKENLPGDPTSNATSRGAEGP---------LPPPSMPAVAGAAGGLALL- 238
            ++G    + P     P  P   A   GA+GP         L PP      G +G   +  
Sbjct: 1059 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1118

Query: 239  LLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIAL 297
              GV G  G    +    +P E   PGP G  G  G  G  G  G       PGE G   
Sbjct: 1119 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1178

Query: 298  RGGGAAD-----PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            + G   D      P  P     +G+ G P  + + GP  SP
Sbjct: 1179 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1219



 Score = 35.4 bits (80), Expect = 0.074
 Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 37/146 (25%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G   LPG+    +  RG  GP  PP +P   G  G     + G  G  G++       
Sbjct: 489 EIGPRGLPGE----SGPRGLLGPKGPPGIPGPPGVRG-----MDGPQGPKGSL------- 532

Query: 257 KPSESRHPG-PGSFGRGGSLGL-GGGGGMGPR-----EAEPGELGIALRGGGAADPPFCP 309
                  PG PG  G  G+ GL G  G +GP      + +PG  G+     G+  PP  P
Sbjct: 533 --GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP----GSDGPPGHP 586

Query: 310 HYEKVSGDYGHPVYIVQDGP--PQSP 333
             E   G  G+       GP  PQ P
Sbjct: 587 GKEGPPGTKGN------QGPSGPQGP 606



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 16/146 (10%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     +PG++   G+   +    G  GP+ P   P  
Sbjct: 958  QGPVGLPGPAGPPGVAGEDGDKGEVG--DPGQKGTKGNKGEHGPP-GPPGPIGPVGQPGA 1014

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLG-LGGGGGM 283
            AGA G       G  G  G    +        +  PGP    G  G  G  G  G  G M
Sbjct: 1015 AGADGE-----PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1069

Query: 284  GPREAEPGELGIALRGGGAADPPFCP 309
            GP    PG  G A  G   AD P  P
Sbjct: 1070 GP-PGPPGPRGPA--GPNGADGPQGP 1092



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 50/190 (26%), Positives = 67/190 (35%), Gaps = 29/190 (15%)

Query: 168  GQSPRGGAVPRKPVSEMPMERDRGAAHSLEP----------------GKENLPGD--PTS 209
            G   +G   P  P        +RGAA S  P                G++ +PG+  P  
Sbjct: 891  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 950

Query: 210  NATSRGAEGP--LPPPS-MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP 266
                 G +GP  LP P+  P VAG  G       G  G  G    +  + +      PGP
Sbjct: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGD-----KGEVGDPGQKGTKGNKGEHGPPGPPGP 1005

Query: 267  -GSFGRGGSLGLGG-GGGMGPREAEPGELGIALRG-GGAADPPFCPHYEKVSGDYGHPVY 323
             G  G+ G+ G  G  G  GP+     +     RG  G   P         SG+ G    
Sbjct: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD 1065

Query: 324  IVQDGPPQSP 333
            +   GPP  P
Sbjct: 1066 VGPMGPPGPP 1075



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 35/127 (27%), Positives = 46/127 (36%), Gaps = 10/127 (7%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSR--GAEGPLPPPSMPAV 228
            PRG A P    ++ P     G  +   PG++  PG+  S       G +GP         
Sbjct: 1077 PRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1134

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPRE 287
            +G  G       G  G  G       +  P     PG PG  G GG  G  G  G    +
Sbjct: 1135 SGQPGEP-----GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1189

Query: 288  AEPGELG 294
             EPG+ G
Sbjct: 1190 GEPGQPG 1196



 Score = 32.0 bits (71), Expect = 0.82
 Identities = 55/200 (27%), Positives = 67/200 (33%), Gaps = 42/200 (21%)

Query: 159 RGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGD--PTSNATSRGA 216
           +G   +L  G    G   P  P   +     +G      PG    PG+  P   A   G+
Sbjct: 278 KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG-----NPGPVGDPGERGPPGRAGLPGS 332

Query: 217 EGPLPPPS----MPAVAGAAGG----------------LALLLLGVAGAGGAMCWRRRRA 256
           +G   PP     +P   G+ GG                L    L + G  G M +  R  
Sbjct: 333 DGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR-- 390

Query: 257 KPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEK 313
            P     PG PG  G  G LG  G  G       PG+ G   R G  GA   P  P    
Sbjct: 391 -PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP---G 446

Query: 314 VSGDYGHPVYIVQDGPPQSP 333
           V GD G       DG P  P
Sbjct: 447 VKGDRGF------DGLPGLP 460


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 49/149 (32%), Positives = 64/149 (42%), Gaps = 27/149 (18%)

Query: 197  EPGKENLPGDPTS-------NATSR-GAEGPLPPPSMPAVAGAAGGLALL----LLGVAG 244
            +PG + L G P S        AT + G  GP+ PP +P + G AG         L+G+ G
Sbjct: 1361 KPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIG 1420

Query: 245  AGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIA-LRGGGA 302
              G       + +  +   PGP GS G+ G +G+ G  G       PG  G A  +G   
Sbjct: 1421 PPG------EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKG 1474

Query: 303  ADPPFCPHYEK-VSGDYGHPVYIVQDGPP 330
            A  P  P  EK V G  GHP      GPP
Sbjct: 1475 ATGPGGPKGEKGVQGPPGHP------GPP 1497



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 47/160 (29%), Positives = 56/160 (35%), Gaps = 29/160 (18%)

Query: 198  PGKENLPGDPTSNATS--RGAEGPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCW 251
            PGK+ LPG P        +G  GP  PP +    GAAG    +      G  G  G    
Sbjct: 897  PGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGL 956

Query: 252  RRRRAKPSESRHPGP-GSFGRGGSLGLGG----------GGGMGPREAE----------- 289
                 K      PGP G+ G+ G  GL G           GG G +  E           
Sbjct: 957  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016

Query: 290  PGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP 329
            PGE G A   GG   PP  P  +   G  G      + GP
Sbjct: 1017 PGERGAA-GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 1055



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 35/112 (31%), Positives = 42/112 (37%), Gaps = 6/112 (5%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-GLALLLLGVAGAGGAMCWRRRRAK 257
            G + LPG P+      G  GP+ PP  P   G AG   A    G  G  G +     + +
Sbjct: 1156 GLQGLPG-PSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 258  PSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADP 305
            P ES  PG    PG  G  G  G  G  G       PG  G     G   +P
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/161 (27%), Positives = 57/161 (35%), Gaps = 16/161 (9%)

Query: 189  DRGAAHSLEPGKENLPGDPTSNATSRGAEGP---------LPPPSMPAVAGAAGGLALL- 238
            ++G    + P     P  P   A   GA+GP         L PP      G +G   +  
Sbjct: 1166 EKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQG 1225

Query: 239  LLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIAL 297
              GV G  G    +    +P E   PGP G  G  G  G  G  G       PGE G   
Sbjct: 1226 EPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRG 1285

Query: 298  RGGGAAD-----PPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            + G   D      P  P     +G+ G P  + + GP  SP
Sbjct: 1286 QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSP 1326



 Score = 35.4 bits (80), Expect = 0.074
 Identities = 44/146 (30%), Positives = 57/146 (39%), Gaps = 37/146 (25%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           E G   LPG+    +  RG  GP  PP +P   G  G     + G  G  G++       
Sbjct: 596 EIGPRGLPGE----SGPRGLLGPKGPPGIPGPPGVRG-----MDGPQGPKGSL------- 639

Query: 257 KPSESRHPG-PGSFGRGGSLGL-GGGGGMGPR-----EAEPGELGIALRGGGAADPPFCP 309
                  PG PG  G  G+ GL G  G +GP      + +PG  G+     G+  PP  P
Sbjct: 640 --GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP----GSDGPPGHP 693

Query: 310 HYEKVSGDYGHPVYIVQDGP--PQSP 333
             E   G  G+       GP  PQ P
Sbjct: 694 GKEGPPGTKGN------QGPSGPQGP 713



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/146 (29%), Positives = 53/146 (36%), Gaps = 16/146 (10%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     +PG++   G+   +    G  GP+ P   P  
Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVG--DPGQKGTKGNKGEHGPP-GPPGPIGPVGQPGA 1121

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLG-LGGGGGM 283
            AGA G       G  G  G    +        +  PGP    G  G  G  G  G  G M
Sbjct: 1122 AGADGE-----PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1176

Query: 284  GPREAEPGELGIALRGGGAADPPFCP 309
            GP    PG  G A  G   AD P  P
Sbjct: 1177 GP-PGPPGPRGPA--GPNGADGPQGP 1199



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 60/220 (27%), Positives = 73/220 (33%), Gaps = 46/220 (20%)

Query: 139 ATSDGTREGLESLQGGVCLTRGMKVLLRVGQSPRGGAVPRKPVSEMPMERDRGAAHSLEP 198
           A S     G   L+G     +G   +L  G    G   P  P   +     +G      P
Sbjct: 369 AHSGAAAHGPRGLKG----EKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQG-----NP 419

Query: 199 GKENLPGD--PTSNATSRGAEGPLPPPS----MPAVAGAAGG----------------LA 236
           G    PG+  P   A   G++G   PP     +P   G+ GG                L 
Sbjct: 420 GPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQ 479

Query: 237 LLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGI 295
              L + G  G M +  R   P     PG PG  G  G LG  G  G       PG+ G 
Sbjct: 480 QARLALRGPPGPMGYTGR---PGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGR 536

Query: 296 ALRGG--GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             R G  GA   P  P    V GD G       DG P  P
Sbjct: 537 RGRAGADGARGMPGDP---GVKGDRGF------DGLPGLP 567



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 50/190 (26%), Positives = 67/190 (35%), Gaps = 29/190 (15%)

Query: 168  GQSPRGGAVPRKPVSEMPMERDRGAAHSLEP----------------GKENLPGD--PTS 209
            G   +G   P  P        +RGAA S  P                G++ +PG+  P  
Sbjct: 998  GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIG 1057

Query: 210  NATSRGAEGP--LPPPS-MPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP 266
                 G +GP  LP P+  P VAG  G       G  G  G    +  + +      PGP
Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGD-----KGEVGDPGQKGTKGNKGEHGPPGPPGP 1112

Query: 267  -GSFGRGGSLGLGG-GGGMGPREAEPGELGIALRG-GGAADPPFCPHYEKVSGDYGHPVY 323
             G  G+ G+ G  G  G  GP+     +     RG  G   P         SG+ G    
Sbjct: 1113 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGD 1172

Query: 324  IVQDGPPQSP 333
            +   GPP  P
Sbjct: 1173 VGPMGPPGPP 1182



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 35/127 (27%), Positives = 46/127 (36%), Gaps = 10/127 (7%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSR--GAEGPLPPPSMPAV 228
            PRG A P    ++ P     G  +   PG++  PG+  S       G +GP         
Sbjct: 1184 PRGPAGPNG--ADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGE 1241

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPRE 287
            +G  G       G  G  G       +  P     PG PG  G GG  G  G  G    +
Sbjct: 1242 SGQPGEP-----GPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED 1296

Query: 288  AEPGELG 294
             EPG+ G
Sbjct: 1297 GEPGQPG 1303


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 44/131 (33%), Positives = 52/131 (39%), Gaps = 25/131 (19%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPS--------MPAVAGAAGGLALLLLGVAGAGGAM 249
           PG   LPG P   + ++G  G   PP         MP + G  G       G AG  G +
Sbjct: 283 PGAAGLPG-PQGPSGAKGEPGTRGPPGLIGPTGYGMPGLPGPKGDR-----GPAGVPGLL 336

Query: 250 CWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFC 308
                R +P E   PG  G  G GG  GL G  G+  R   PG  G A  GG    PP  
Sbjct: 337 ---GDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGG----PPGV 389

Query: 309 PHYEKVSGDYG 319
           P    + GD G
Sbjct: 390 P---GIRGDQG 397



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 57/191 (29%), Positives = 69/191 (36%), Gaps = 30/191 (15%)

Query: 163 VLLRVGQSPR-------GGAVPRKPVSEM-PMERD-------RGAAHSLEPGKENLPGDP 207
           ++L +G  PR       GGA    PV  + PM++         G    LE     LP D 
Sbjct: 16  LVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGKGQYLEMPLPLLPMDL 75

Query: 208 TSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-- 265
                  G  GP  PP  P   G  G     L G  G  G   +  R  K      PG  
Sbjct: 76  KGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGF-SRMGKAGPPGLPGKV 134

Query: 266 --PGSFGRGGSLGLGGGGGM-GP--REAEPGELGIALRG-GGAADPPFCPHYEKVSGDYG 319
             PG  G  G  G+ G  G+ GP      PG  GI + G  GA   P  P ++   G  G
Sbjct: 135 GPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQG 194

Query: 320 HPVYIVQDGPP 330
            P      GPP
Sbjct: 195 EP------GPP 199



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 40/139 (28%), Positives = 51/139 (36%), Gaps = 25/139 (17%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           +PG + +PG P      +G  GP   P  P   G  G   +   G+ GA G      +  
Sbjct: 174 KPGAQGVPGPPGF----QGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAPG------QGG 223

Query: 257 KPSESRHPGPGSFGRGGSLGLGGGGG----------MGPREAEPGELG----IALRGGGA 302
            P     PGP   G+ G  GL G  G           GPR  EPG +G      + G G 
Sbjct: 224 APGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPR-GEPGAVGPKGPPGVDGVGV 282

Query: 303 ADPPFCPHYEKVSGDYGHP 321
                 P  +  SG  G P
Sbjct: 283 PGAAGLPGPQGPSGAKGEP 301



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 45/168 (26%), Positives = 57/168 (33%), Gaps = 46/168 (27%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           P  E  PG P      RG +GP      P V G          G+ GA G       + +
Sbjct: 377 PKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGER--------GLPGAHGPPGPTGPKGE 428

Query: 258 PSESRHPG----PGSFGRGGSLGL----------------GGGGGMGPR-----EAEPGE 292
           P  +  PG     G+ G+ G LGL                G  G +GP+     + EPG 
Sbjct: 429 PGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGL 488

Query: 293 LGIALRG-------GGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
            G    G        G   PP  P    ++G  G P      GPP  P
Sbjct: 489 PGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPP------GPPGPP 530



 Score = 35.0 bits (79), Expect = 0.096
 Identities = 43/142 (30%), Positives = 53/142 (37%), Gaps = 17/142 (11%)

Query: 165 LRVGQSPRGGAVPRKPVSEMPMERDRGAAHSL--------EPGKENLPGDPTSNATSRGA 216
           +R  Q P G A   KP   +P ER    AH          EPG    PG P   A + G 
Sbjct: 392 IRGDQGPSGLA--GKP--GVPGERGLPGAHGPPGPTGPKGEPGFTGRPGGP-GVAGALGQ 446

Query: 217 EGPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRG 272
           +G L  P  P + G +G   L      +G  G  G          P E R   PG+ G  
Sbjct: 447 KGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPT 506

Query: 273 GSLGLGGGGGMGPREAEPGELG 294
           G  G+ G  G+      PG  G
Sbjct: 507 GPPGVPGSPGITGPPGPPGPPG 528



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 43/156 (27%), Positives = 51/156 (32%), Gaps = 10/156 (6%)

Query: 180 PVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSR--GAEGP--LPPPSMPAVAGAAGGL 235
           P  E     DRG       G+  LPG P         G  GP  L  P +  + GA G  
Sbjct: 192 PQGEPGPPGDRGLKGDNGVGQPGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDK 251

Query: 236 ALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELG- 294
                G +G  G    R           PG    G  G+ GL G  G    + EPG  G 
Sbjct: 252 -----GESGPPGVPGPRGEPGAVGPKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGP 306

Query: 295 IALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
             L G      P  P  +   G  G P  +   G P
Sbjct: 307 PGLIGPTGYGMPGLPGPKGDRGPAGVPGLLGDRGEP 342



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 16/133 (12%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           +PG    PG       SR   G   PP +P   G  G       G+ G  G    +  R 
Sbjct: 104 KPGLHGQPGPAGPPGFSR--MGKAGPPGLPGKVGPPGQP-----GLRGEPGIRGDQGLRG 156

Query: 257 KPSESRHPGPGSF---GRGGSLGLGGGGGM----GPREAEPGELG-IALRGGGAADPPFC 308
            P     PGP      G+ G+ G+ G  G     GP + EPG  G   L+G      P  
Sbjct: 157 PPGPPGLPGPSGITIPGKPGAQGVPGPPGFQGEPGP-QGEPGPPGDRGLKGDNGVGQPGL 215

Query: 309 PHYEKVSGDYGHP 321
           P      G  G P
Sbjct: 216 PGAPGQGGAPGPP 228



 Score = 28.5 bits (62), Expect = 9.0
 Identities = 23/64 (35%), Positives = 26/64 (40%), Gaps = 6/64 (9%)

Query: 191 GAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-----GLALLLLGVAGA 245
           G   + EPG    P  P     S G  GP  PP  P   GA G     G+A L L   G 
Sbjct: 493 GEGRAGEPGTAG-PTGPPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGV 551

Query: 246 GGAM 249
            GA+
Sbjct: 552 EGAV 555


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 46/157 (29%), Positives = 57/157 (36%), Gaps = 31/157 (19%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLL-------------GVA 243
            EPG+   PG        +G  GP  PP  P   G  G +    L             G +
Sbjct: 1003 EPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFS 1062

Query: 244  GAGGAMCWRRRRAKPS----------ESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGE 292
            G  GA   +  +  P+          E   PG PG FG  G  GL   G  GPR   PG 
Sbjct: 1063 GIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGL--PGIQGPR-GSPGR 1119

Query: 293  LGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGP 329
             G      G++ PP CP    + G  G P  +   GP
Sbjct: 1120 PG----PPGSSGPPGCPGDHGMPGLRGQPGEMGDPGP 1152



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 47/155 (30%), Positives = 56/155 (36%), Gaps = 26/155 (16%)

Query: 189 DRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGG 247
           D    H   PGK  L G P       G +GP   P  P   G AG    L L G  G  G
Sbjct: 761 DPAFGHLGPPGKRGLSGVP-------GIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREG 813

Query: 248 AMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELG----IALRG--- 299
              +      P  S   G PG  G+ G  G  G  G    + +PG++G      ++G   
Sbjct: 814 HAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG 873

Query: 300 ----GGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
                GA  PP  P      GD G P      GPP
Sbjct: 874 LPGRPGAHGPPGLPGIPGPFGDDGLP------GPP 902



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 40/138 (28%), Positives = 53/138 (38%), Gaps = 26/138 (18%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG+  +PG P S      A G    P  P + GA G     L G+ G+    C       
Sbjct: 419 PGEAGIPGRPDS------APGKPGKPGSPGLPGAPG-----LQGLPGSSVIYC------- 460

Query: 258 PSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVS 315
                +PGP    +G    +G  GG GP+  +  E   A   G  G   PP  P  +   
Sbjct: 461 --SVGNPGP----QGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSK 514

Query: 316 GDYGHPVYIVQDGPPQSP 333
           GD G P ++   G P  P
Sbjct: 515 GDLGLPGWLGTKGDPGPP 532



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 47/156 (30%), Positives = 55/156 (35%), Gaps = 34/156 (21%)

Query: 198 PGKENLPGDPTSNAT--SRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
           PG+  LPG P S      +G  G + PP    + G  G     L G  GA G        
Sbjct: 836 PGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPG-----LPGRPGAHGPPGLPGIP 890

Query: 256 AKPSESRHPGP----------GSFGRGGSLGLGGGGGMGPREAEPGELGIA-------LR 298
               +   PGP          G  G  G  G  G  G    + EPGE G++       LR
Sbjct: 891 GPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLR 950

Query: 299 GG-GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           G  GA  PP         GD G    I Q G P  P
Sbjct: 951 GAKGAIGPP---------GDEGEMAIISQKGTPGEP 977



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 44/147 (29%), Positives = 52/147 (35%), Gaps = 22/147 (14%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            +PG E  PG       ++G  G      +P   G  G    +  G  G  G M    ++ 
Sbjct: 922  KPGAEGCPG-------AKGEPGEKGMSGLPGDRGLRGAKGAI--GPPGDEGEMAIISQKG 972

Query: 257  KPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIA--LRG-------GGAADPP 306
             P E   PGP G  G  G  G  G  GM  R  EPG  G     RG        G   PP
Sbjct: 973  TPGE---PGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPP 1029

Query: 307  FCPHYEKVSGDYGHPVYIVQDGPPQSP 333
              P    + G  G P      G P SP
Sbjct: 1030 GPPGSTGLRGFIGFPGLPGDQGEPGSP 1056



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 38/113 (33%), Positives = 43/113 (38%), Gaps = 13/113 (11%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG     GDP       GAEGP   P +P   GA+G       G  GA G M   R +  
Sbjct: 520 PGWLGTKGDPGPP----GAEGP---PGLPGKHGASGPP-----GNKGAKGDMVVSRVKGH 567

Query: 258 PSESRHPGPGSF-GRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCP 309
             E    GP  F G+ GS G  G  G       PG+   A  GG     P  P
Sbjct: 568 KGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGP 620



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 37/124 (29%), Positives = 46/124 (37%), Gaps = 19/124 (15%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G +   GDP S+    G +G    P  P   GA+G   L   G+ G  G+          
Sbjct: 1069 GPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLP--GIQGPRGS---------- 1116

Query: 259  SESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGD 317
                 PG PG  G  G  G  G  GM     +PGE+G     G   DP   P    + G 
Sbjct: 1117 -----PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGI-PGPPGIKGP 1170

Query: 318  YGHP 321
             G P
Sbjct: 1171 SGSP 1174



 Score = 36.6 bits (83), Expect = 0.033
 Identities = 44/146 (30%), Positives = 52/146 (35%), Gaps = 26/146 (17%)

Query: 198  PGKENLPGDPTSNATS----RGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRR 253
            PG +   GDP S   S    RG +GP  PP      G AG        +   G       
Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPG------- 1258

Query: 254  RRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYE 312
                P +   PGP G  G  G  GL G   +     EPG+ G+     G   PP  P Y+
Sbjct: 1259 ---PPGDQGPPGPDGPRGAPGPPGLPGSVDL--LRGEPGDCGLP-GPPGPPGPPGPPGYK 1312

Query: 313  KVSGDYGHPVYIVQDGP-----PQSP 333
               G  G      Q GP     PQ P
Sbjct: 1313 GFPGCDGKD---GQKGPVGFPGPQGP 1335



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 43/157 (27%), Positives = 51/157 (32%), Gaps = 27/157 (17%)

Query: 176 VPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGL 235
           +P  P    P  +   + H+   G    PG        RGA GP  P   P   G  G  
Sbjct: 123 IPGHPGPPGPRGKPGMSGHNGSRGDPGFPG-------GRGALGPGGPLGHPGEKGEKGNS 175

Query: 236 ALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGI 295
             +L  V G  G                  PG  G  GS G GG  G      EPG +G 
Sbjct: 176 VFILGAVKGIQGD--------------RGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221

Query: 296 ALRGG--GAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
             + G  G    P       V G  G P  + Q G P
Sbjct: 222 PGQPGRPGLKGNPGV----GVKGQMGDPGEVGQQGSP 254



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 24/71 (33%), Positives = 27/71 (38%), Gaps = 14/71 (19%)

Query: 264 PGP----GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYG 319
           PGP    G  G  G +GL G  GM      PG  G      G   P   P +  + G  G
Sbjct: 70  PGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG----DKGDKGPTGVPGFPGLDGIPG 125

Query: 320 HPVYIVQDGPP 330
           HP      GPP
Sbjct: 126 HP------GPP 130


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 45.4 bits (106), Expect = 7e-05
 Identities = 42/143 (29%), Positives = 56/143 (39%), Gaps = 16/143 (11%)

Query: 197  EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
            +PG   LPG P       G EGP+ PP  P + G  G       G  G  G       + 
Sbjct: 929  KPGARGLPG-PRGQLGPEGDEGPMGPPGAPGLEGQPGRKG--FPGRPGLDGV------KG 979

Query: 257  KPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVS 315
            +P +   PGP G  G  G +GL G  G+   + + G +G      G   P     +  + 
Sbjct: 980  EPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMG----PPGVPGPKGSMGHPGMP 1035

Query: 316  GDYGHPVYIVQDGPPQS--PPNI 336
            G  G P      GPP S  PP +
Sbjct: 1036 GGMGTPGEPGPQGPPGSRGPPGM 1058



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 48/162 (29%), Positives = 61/162 (37%), Gaps = 22/162 (13%)

Query: 180  PVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL- 238
            P+    ++ DRG     +PG +   G+        G +GP  PP +  V G  G      
Sbjct: 1196 PMGPDGLKGDRG-----DPGPDGEHGEKGQEGLM-GEDGPPGPPGVTGVRGPEGKSGKQG 1249

Query: 239  ---LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELG 294
                 G  GA G          P +   PG PG  G  GSLG  G  G    + EPG  G
Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAG 1309

Query: 295  IALRGG--GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSPP 334
                 G  G   PP  P  EK  G+ G      +DG  + PP
Sbjct: 1310 YDGHKGIVGPLGPP-GPKGEK--GEQG------EDGKAEGPP 1342



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 42/135 (31%), Positives = 49/135 (36%), Gaps = 17/135 (12%)

Query: 204  PGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRH 263
            P  P     SRG +GP  P   P   G          GVAG  G +  R     P  S  
Sbjct: 1070 PDGPAGEQGSRGLKGPPGPQGRPGRPGQQ--------GVAGERGHLGSRGFPGIPGPSGP 1121

Query: 264  PG----PGSFGRGGSLG-LGGGGGMGPR--EAEPGELGIALRGG--GAADPPFCPHYEKV 314
            PG    PG  G  G  G +G  G MGP+      GE G+    G  G   P   P  + +
Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181

Query: 315  SGDYGHPVYIVQDGP 329
             G  G P      GP
Sbjct: 1182 IGQRGEPGLEGDSGP 1196



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 46/182 (25%), Positives = 64/182 (35%), Gaps = 47/182 (25%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-----GLA-----------LLLLG 241
           PG   LPG P +    RG  GP   P +P   GA G     GL+           + L G
Sbjct: 639 PGLPGLPGIPGARGP-RGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPG 697

Query: 242 VAGAGGAMCWRRRRAKPSESRHPG----------------------------PGSFGRGG 273
           ++G  G    +  +  P  + HPG                            PG  G  G
Sbjct: 698 LSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRG 757

Query: 274 SLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEK--VSGDYGHPVYIVQDGPPQ 331
            +GL G  G+   + E G  G+  + G    P F   + +    G  G+P  +   GPP 
Sbjct: 758 YIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPG 817

Query: 332 SP 333
            P
Sbjct: 818 VP 819



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 41/154 (26%), Positives = 55/154 (35%), Gaps = 27/154 (17%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G + LPG P      +G EG   P  +P   G AG       G  G  G M    +R  P
Sbjct: 1421 GLQGLPG-PRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQ--GDDGDPGPMGPAGKRGNP 1477

Query: 259  SESRHPG-------------PGSFGRGGSLGLGGGGGMGPREAEP---------GELGIA 296
              +  PG             PG  G  G  G  G  G+   + EP         GE+G  
Sbjct: 1478 GVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFP 1537

Query: 297  LRGG--GAADPPFCPHYEKVSGDYGHPVYIVQDG 328
               G  G   PP    ++ + G  G P  + ++G
Sbjct: 1538 GMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEG 1571



 Score = 33.9 bits (76), Expect = 0.21
 Identities = 38/149 (25%), Positives = 56/149 (37%), Gaps = 28/149 (18%)

Query: 197  EPGKENLPGD-----------------PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLL 239
            EPG +  PGD                 P  +   +G +GP  PP +    G  G L   +
Sbjct: 1521 EPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLG--I 1578

Query: 240  LGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALR 298
            LG +G  G    +  R         G PG  GR G  G  G    GP + +  +LG A +
Sbjct: 1579 LGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPG----GPIQLQQDDLGAAFQ 1634

Query: 299  ----GGGAADPPFCPHYEKVSGDYGHPVY 323
                  GA  P    + +++  D G  ++
Sbjct: 1635 TWMDTSGALRPESYSYPDRLVLDQGGEIF 1663



 Score = 33.5 bits (75), Expect = 0.28
 Identities = 37/124 (29%), Positives = 45/124 (36%), Gaps = 8/124 (6%)

Query: 215  GAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGS 274
            G +G +  P MP   G  G       G  G+ G    R  + +       GP   G  GS
Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQ--GPPGSRGPPGMRGAKGRRGPRGPDGPA--GEQGS 1079

Query: 275  LGLGGGGGMGPREAEPGELGIALRGG--GAADPPFCPHYEKVSGDYGHPVYIVQDGP--P 330
             GL G  G   R   PG+ G+A   G  G+   P  P      G  G P      GP  P
Sbjct: 1080 RGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGP 1139

Query: 331  QSPP 334
              PP
Sbjct: 1140 IGPP 1143



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 31/101 (30%), Positives = 39/101 (38%), Gaps = 9/101 (8%)

Query: 198  PGKENLPGDP--TSNATSRGAEGPLPPPSMPAVAGAAG--GLALLLLGVAGAGGAMCWRR 253
            PG+    G+P        +G  GPL PP      G  G  G A    G  G  G +  R 
Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRG 1355

Query: 254  RRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELG 294
             R +P +     PG  G+ G  GL G  G   +   PG  G
Sbjct: 1356 DRGEPGD-----PGYPGQEGVQGLRGKPGQQGQPGHPGPRG 1391



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 52/197 (26%), Positives = 68/197 (34%), Gaps = 36/197 (18%)

Query: 147 GLESLQGGVCLTRGMKVLLRVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPG 205
           GL    G   L   + VL  +G   P+G       V E  ++ D+G     E G   + G
Sbjct: 811 GLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKG-----EQGVPGVSG 865

Query: 206 DPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG 265
           DP      +G +G    P  P   G  G L     G  G  G++ +            PG
Sbjct: 866 DPGF----QGDKGSQGLPGFPGARGKPGPL-----GKVGDKGSIGF------------PG 904

Query: 266 P-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--------GAADPPFCPHYEKVSG 316
           P G  G  G +G  G  G    + +PG  G+    G        G   PP  P  E   G
Sbjct: 905 PPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPG 964

Query: 317 DYGHPVYIVQDGPPQSP 333
             G P     DG    P
Sbjct: 965 RKGFPGRPGLDGVKGEP 981



 Score = 30.4 bits (67), Expect = 2.4
 Identities = 35/121 (28%), Positives = 40/121 (33%), Gaps = 32/121 (26%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G+  +PGDP              PP  P   G+ G L     G  GA G M         
Sbjct: 1267 GEMGVPGDPG-------------PPGTPGPKGSRGSL-----GPTGAPGRM--------- 1299

Query: 259  SESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDY 318
                   PG  G  G  G+ G  G    + E GE G     G A  PP  P      GD 
Sbjct: 1300 --GAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG---EDGKAEGPPGPPGDRGPVGDR 1354

Query: 319  G 319
            G
Sbjct: 1355 G 1355



 Score = 30.0 bits (66), Expect = 3.1
 Identities = 32/111 (28%), Positives = 43/111 (38%), Gaps = 15/111 (13%)

Query: 198 PGKENLPGDPTSNAT--SRGAEGPLPPPSMPAVAGAAGGLALLLL-------GVAGAGGA 248
           PG+  LPG P         G  GP+  P    + G  G +    L       GV G  G 
Sbjct: 807 PGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGD 866

Query: 249 MCWRRRRAKPSESRHPG----PGSFGRGGSLG-LGGGGGMGPREAEPGELG 294
             ++  +        PG    PG  G+ G  G +G  G  GP E  PG++G
Sbjct: 867 PGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGP-EGFPGDIG 916


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 49/186 (26%), Positives = 63/186 (33%), Gaps = 29/186 (15%)

Query: 172 RGGAVPRKPVSEMPMERDRGAAHSLEP----GKENLPGDP-----------TSNATSRGA 216
           +G A P  P  E     + GA   + P    G+   PG P           T  A   G 
Sbjct: 277 KGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGP 336

Query: 217 EGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG----PGSFGRG 272
            GP  PP  P   GA G       G  G+ G    R     P  +   G    PG+ G+ 
Sbjct: 337 TGPAGPPGFPGAVGAKGEAG--PQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQP 394

Query: 273 GSLGLGGGGGMGPREAEPGELGIALRGGGAADP--------PFCPHYEKVSGDYGHPVYI 324
           G+ G  G  G+      PG  G +   G    P        P  P  +  +G  G P  +
Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454

Query: 325 VQDGPP 330
              GPP
Sbjct: 455 GVQGPP 460



 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 55/182 (30%), Positives = 58/182 (31%), Gaps = 33/182 (18%)

Query: 166  RVGQ-SPRGGAVPRKPVSEMPMERDRGAAHSL----EPGKENLPGDP--TSNATSRGAEG 218
            RVG   P G A P  P      E  +G          PG+   PG P       S GA+G
Sbjct: 882  RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941

Query: 219  PLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----------GS 268
            P   P  P   G AG       GV G  G    R     P  S  PG           G 
Sbjct: 942  PAGAPGTPGPQGIAG-----QRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGP 996

Query: 269  FGRGGSLGLGGGGGMGPREAEPGELGIALRGG-----------GAADPPFCPHYEKVSGD 317
             G  G  GL G  G   RE  PG  G   R G           G A PP  P      G 
Sbjct: 997  PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP 1056

Query: 318  YG 319
             G
Sbjct: 1057 VG 1058



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 46/163 (28%), Positives = 54/163 (33%), Gaps = 10/163 (6%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSL-EPGKENLPGDP--TSNATSRGAEGPLPPPSM 225
           Q P G   P+    E      +G   +  EPG   + G P        RGA G   P  +
Sbjct: 421 QGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGL 480

Query: 226 PAVAGAAGGLALL-LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGM 283
           P   G  GG       G  G  G       R  P  +   G PG  GR G  GL G  G+
Sbjct: 481 PGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGL 540

Query: 284 GPREAEPGELGIALRGG-----GAADPPFCPHYEKVSGDYGHP 321
                 PG  G     G     G   PP  P     +G  G P
Sbjct: 541 TGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFP 583



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/165 (29%), Positives = 58/165 (35%), Gaps = 30/165 (18%)

Query: 189 DRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG-----GLALLLLGVA 243
           DRG A     G +   G P  +   RG  GP+ PP      G  G     G A    G  
Sbjct: 744 DRGDA-----GPKGADGSPGKDGV-RGLTGPIGPPGPAGAPGDKGESGPSGPA----GPT 793

Query: 244 GAGGAMCWRRRRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG-- 300
           GA GA   R     P  +   GP G+ G+ G+ G  G  G       PG  G A   G  
Sbjct: 794 GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853

Query: 301 ------------GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
                       G+A PP    +   +G  G P      GPP  P
Sbjct: 854 GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPP 898



 Score = 38.9 bits (89), Expect = 0.007
 Identities = 42/134 (31%), Positives = 52/134 (38%), Gaps = 27/134 (20%)

Query: 197 EPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           +PG +  PGD        GA+G   PP     AG  G +  +  G  GA GA    R  A
Sbjct: 822 QPGAKGEPGDA-------GAKGDAGPPGPAGPAGPPGPIGNV--GAPGAKGA----RGSA 868

Query: 257 KPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSG 316
            P       PG+ G  G+ G  G  G       PG  G A + GG       P  E  +G
Sbjct: 869 GP-------PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG-----PRGE--TG 914

Query: 317 DYGHPVYIVQDGPP 330
             G P  +   GPP
Sbjct: 915 PAGRPGEVGPPGPP 928



 Score = 38.5 bits (88), Expect = 0.009
 Identities = 39/134 (29%), Positives = 51/134 (38%), Gaps = 24/134 (17%)

Query: 171  PRGGAVPRKPVSEMPMERDRG----AAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMP 226
            P+G A  R  V       +RG       S EPGK+     P+  +  RG  GP+ PP + 
Sbjct: 951  PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQG----PSGASGERGPPGPMGPPGLA 1006

Query: 227  AVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPR 286
               G +G          GA G        A+ S  R   PG+ G  G  G  G  G    
Sbjct: 1007 GPPGESGR--------EGAPG--------AEGSPGRDGSPGAKGDRGETGPAGPPGAPGA 1050

Query: 287  EAEPGELGIALRGG 300
               PG +G A + G
Sbjct: 1051 PGAPGPVGPAGKSG 1064



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 51/200 (25%), Positives = 62/200 (31%), Gaps = 53/200 (26%)

Query: 169 QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
           + P+G   PR P         RG A    PG++ +PG P       G  GP  PP  P  
Sbjct: 111 EGPKGDTGPRGP---------RGPAGP--PGRDGIPGQP-------GLPGPPGPPGPPGP 152

Query: 229 AGAAGGLALLLL-----------------------GVAGAGGAMCWRRRRAKPSESRHPG 265
            G  G  A  L                        G+ G  GA   +  +  P E   PG
Sbjct: 153 PGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG 212

Query: 266 ----------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPH--YEK 313
                     PG  G+ G  G  G  G       PG  G     G A  P    H  +  
Sbjct: 213 ASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSG 272

Query: 314 VSGDYGHPVYIVQDGPPQSP 333
           + G  G        G P SP
Sbjct: 273 LDGAKGDAGPAGPKGEPGSP 292



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 32/107 (29%), Positives = 40/107 (37%), Gaps = 10/107 (9%)

Query: 198 PGKENLPG-----DPTSNATSRGAEGPLPPPSMPAVAGAAGGLALL-LLGVAGAGGAMCW 251
           PG    PG      P   A  RG+ GP  P   P  AG  G   L    G+ G+ G+   
Sbjct: 490 PGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGP 549

Query: 252 RRRRAKPSESRHPG----PGSFGRGGSLGLGGGGGMGPREAEPGELG 294
             +   P  +   G    PG  G  G  G+ G  G      EPG+ G
Sbjct: 550 DGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAG 596



 Score = 36.2 bits (82), Expect = 0.043
 Identities = 47/153 (30%), Positives = 56/153 (36%), Gaps = 29/153 (18%)

Query: 176 VPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGL 235
           VP  P +  P  +D       E G +  PG P   A  RG +GP   P    + G AG  
Sbjct: 600 VPGPPGAVGPAGKDG------EAGAQGPPG-PAGPAGERGEQGPAGSPGFQGLPGPAGP- 651

Query: 236 ALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLGL-GGGGGMGPREAE- 289
                G AG  G       +  P +   PGP    G  G  G  G+ G  G  GPR A  
Sbjct: 652 ----PGEAGKPG------EQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701

Query: 290 -PGELGIALRGGGAADPPFCPHYEKVSGDYGHP 321
            PG  G      G A  P  P  +   G  G P
Sbjct: 702 APGNDG----AKGDAGAPGAPGSQGAPGLQGMP 730



 Score = 33.1 bits (74), Expect = 0.37
 Identities = 33/101 (32%), Positives = 37/101 (36%), Gaps = 5/101 (4%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGA-AHSLEPGKENLPGDPTSNATS--RGAEGPLPPPSM 225
            + P G   PR    E   + DRG   H    G +  PG P S       GA GP  P   
Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP 1143

Query: 226  PAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP 266
            P  AGA G     L G+ G  G    R R         PGP
Sbjct: 1144 PGSAGAPGKDG--LNGLPGPIGPPGPRGRTGDAGPVGPPGP 1182



 Score = 30.8 bits (68), Expect = 1.8
 Identities = 41/147 (27%), Positives = 45/147 (30%), Gaps = 22/147 (14%)

Query: 198  PGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
            PG    PG   P   +  RG  GP  P       GA G       G  G  G       +
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGP-----AGPQGPRGDKGETGEQ 1102

Query: 256  AKPSESRHPG-------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG--GAADPP 306
                   H G       PG  G  G  G  G  G       PG  G   + G  G   P 
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162

Query: 307  FCPHYEKVSGDYGHPVYIVQDGPPQSP 333
              P     +GD G PV     GPP  P
Sbjct: 1163 GPPGPRGRTGDAG-PV-----GPPGPP 1183


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 22/137 (16%)

Query: 198  PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
            PGK+ LPG P     + G +G   PP    V G  G       G  G  G          
Sbjct: 951  PGKDGLPGHPGQRGET-GFQGKTGPPGPGGVVGPQGPT-----GETGPIG---------- 994

Query: 258  PSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGD 317
              E  HPGP   G  G  GL G  G    + +PG  GI+ + G A    F P    + G 
Sbjct: 995  --ERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGA 1049

Query: 318  YGHPVYIVQDGPPQSPP 334
             G P     +G PQ PP
Sbjct: 1050 QGAPGLKGGEG-PQGPP 1065



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 21/154 (13%)

Query: 183 EMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGV 242
           +M ++ DRG    + P  E+ P  P      +G  GP   P     AG  G      LGV
Sbjct: 803 DMGLKGDRGEVGQIGPRGEDGPEGP------KGRAGPTGDPGPSGQAGEKG-----KLGV 851

Query: 243 AGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGG 301
            G  G   +  R+     +  PG PG+ G  G+ G+ G  G   +    G  G      G
Sbjct: 852 PGLPG---YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG----SRG 904

Query: 302 AADPPFCPHYEKVSGDYGHPVYIVQDGP--PQSP 333
           A  P   P  +  SG  G P    + GP  PQ P
Sbjct: 905 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 938



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 22/181 (12%)

Query: 169 QSPRGGAVPRKPVSEMPMERDR-----GAAHSLEPGK------ENLPGDPTSNATSRGAE 217
           Q PRG   P  P  + P +R R     G     EPG       + LPG P      RG  
Sbjct: 573 QGPRGVQGPPGPTGK-PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG-HRGER 630

Query: 218 GPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRG 272
           GP  PP  P   G  G    +    L G AG  G +  R     P +    G  G  G  
Sbjct: 631 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPK 690

Query: 273 GSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQS 332
           G++G  G  G   ++  PG  G+     G   P   P  +   G  G       DGPP  
Sbjct: 691 GNMGPQGEPGPPGQQGNPGPQGLP----GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 746

Query: 333 P 333
           P
Sbjct: 747 P 747



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 45/152 (29%), Positives = 54/152 (35%), Gaps = 18/152 (11%)

Query: 198  PGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
            PG +  PGD  P  N    G  G   PP  P  AG  G     + G  G  G        
Sbjct: 1305 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-----VGGDKGEDGDPGQPGPP 1359

Query: 256  AKPSESRHPGP-------GSFGRGGSLGLGGGGGMGPREAEPGELG-IALRG-GGAADPP 306
                E+  PGP       G+ G  G  G  G  G    E  PG+ G +  +G  G   P 
Sbjct: 1360 GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1419

Query: 307  FCPHYEKVSGDYGHPVYIVQDGP--PQSPPNI 336
                     G+ G P    QDGP  P  PP +
Sbjct: 1420 GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1451



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 46/176 (26%), Positives = 56/176 (31%), Gaps = 30/176 (17%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATS-----RGAEGPLPPP 223
            Q P G   P+ P   +      G     EPG+   PG P           RG +G   PP
Sbjct: 1242 QGPNGADGPQGPPGSVGSVG--GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299

Query: 224  SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGG 282
                  GA G          G  G       +  P     PG PG  G  G  G  G GG
Sbjct: 1300 GAAGPPGAKGP--------PGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1345

Query: 283  MGPREAEPGELGIALRGG--------GAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
                + +PG+ G     G        G   PP     E   G+ G       +GPP
Sbjct: 1346 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1401



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/165 (29%), Positives = 61/165 (36%), Gaps = 25/165 (15%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G   P+ P  +   E  RG    +  G++ LPG     A   G  GP+ PP +P + G  
Sbjct: 1405 GPVGPQGPAGKPGPEGLRGIPGPV--GEQGLPGA----AGQDGPPGPMGPPGLPGLKGDP 1458

Query: 233  GGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREA 288
            G         L+G+ G  G    +  R  P       PG+ G GG  G  G  G      
Sbjct: 1459 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1516

Query: 289  EPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             PG  G     G        P  +K  GD G P      GPP SP
Sbjct: 1517 LPGPQGPKGNKGSTG-----PAGQK--GDSGLP------GPPGSP 1548



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 47/177 (26%), Positives = 63/177 (35%), Gaps = 32/177 (18%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     EPG++   GD       +G  GP  PP +   
Sbjct: 1119 QGPVGLPGPAGPAGSPGEDGDKGEIG--EPGQKGSKGD-------KGENGPPGPPGLQGP 1169

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSF-GRGGSLGLGGGGGMGPRE 287
             GA         G+AG  G    R ++    +    G   F G  G +GL G  G    +
Sbjct: 1170 VGAP--------GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1221

Query: 288  AEPGELG----------IALRGGGAADPPFCPHYEKVS----GDYGHPVYIVQDGPP 330
             E G++G             +G   AD P  P     S    G+ G P      GPP
Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1278



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 40/146 (27%), Positives = 47/146 (32%), Gaps = 34/146 (23%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G + LPG P     + G  GP+ PP  P   G  G       G  G  G           
Sbjct: 1210 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPN-----GADGPQGP---------- 1253

Query: 259  SESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG-----------GAADPPF 307
                   PGS G  G +G  G  G       PGE G+    G           GAA PP 
Sbjct: 1254 -------PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1306

Query: 308  CPHYEKVSGDYGHPVYIVQDGPPQSP 333
                    G  G+P  +   G P  P
Sbjct: 1307 AKGPPGDDGPKGNPGPVGFPGDPGPP 1332



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 41/147 (27%), Positives = 50/147 (34%), Gaps = 27/147 (18%)

Query: 172 RGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGA 231
           RG   P  P  +  M  + G     E G   LPG+    A  RG  GP   P  P   G 
Sbjct: 630 RGPQGPPGPPGDDGMRGEDG-----EIGPRGLPGE----AGPRGLLGPRGTPGAPGQPGM 680

Query: 232 AGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-------------GSFGRGGSLGLG 278
           AG     + G  G  G M  +     P +  +PGP             G  G  G  GL 
Sbjct: 681 AG-----VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 735

Query: 279 GGGGMGPREAEPGELGIALRGGGAADP 305
           G  G       PG+ G +   G    P
Sbjct: 736 GLPGADGPPGHPGKEGQSGEKGALGPP 762



 Score = 29.3 bits (64), Expect = 5.3
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 21/110 (19%)

Query: 199 GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG--GLALLL---LGVAGAGGAMCWRR 253
           G    PGDP       G  GP   P +P   G  G  G  L+L    G  G+ G     +
Sbjct: 472 GPTGPPGDP-------GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 524

Query: 254 --------RRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELG 294
                   ++A+ +    PGP G  GR G +G  G  G      +PG  G
Sbjct: 525 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 574


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 22/137 (16%)

Query: 198  PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
            PGK+ LPG P     + G +G   PP    V G  G       G  G  G          
Sbjct: 900  PGKDGLPGHPGQRGET-GFQGKTGPPGPGGVVGPQGPT-----GETGPIG---------- 943

Query: 258  PSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGD 317
              E  HPGP   G  G  GL G  G    + +PG  GI+ + G A    F P    + G 
Sbjct: 944  --ERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGA 998

Query: 318  YGHPVYIVQDGPPQSPP 334
             G P     +G PQ PP
Sbjct: 999  QGAPGLKGGEG-PQGPP 1014



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 21/154 (13%)

Query: 183 EMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGV 242
           +M ++ DRG    + P  E+ P  P      +G  GP   P     AG  G      LGV
Sbjct: 752 DMGLKGDRGEVGQIGPRGEDGPEGP------KGRAGPTGDPGPSGQAGEKG-----KLGV 800

Query: 243 AGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGG 301
            G  G   +  R+     +  PG PG+ G  G+ G+ G  G   +    G  G      G
Sbjct: 801 PGLPG---YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG----SRG 853

Query: 302 AADPPFCPHYEKVSGDYGHPVYIVQDGP--PQSP 333
           A  P   P  +  SG  G P    + GP  PQ P
Sbjct: 854 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 887



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 22/181 (12%)

Query: 169 QSPRGGAVPRKPVSEMPMERDR-----GAAHSLEPGK------ENLPGDPTSNATSRGAE 217
           Q PRG   P  P  + P +R R     G     EPG       + LPG P      RG  
Sbjct: 522 QGPRGVQGPPGPTGK-PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG-HRGER 579

Query: 218 GPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRG 272
           GP  PP  P   G  G    +    L G AG  G +  R     P +    G  G  G  
Sbjct: 580 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPK 639

Query: 273 GSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQS 332
           G++G  G  G   ++  PG  G+     G   P   P  +   G  G       DGPP  
Sbjct: 640 GNMGPQGEPGPPGQQGNPGPQGLP----GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 695

Query: 333 P 333
           P
Sbjct: 696 P 696



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 45/152 (29%), Positives = 54/152 (35%), Gaps = 18/152 (11%)

Query: 198  PGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
            PG +  PGD  P  N    G  G   PP  P  AG  G     + G  G  G        
Sbjct: 1254 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-----VGGDKGEDGDPGQPGPP 1308

Query: 256  AKPSESRHPGP-------GSFGRGGSLGLGGGGGMGPREAEPGELG-IALRG-GGAADPP 306
                E+  PGP       G+ G  G  G  G  G    E  PG+ G +  +G  G   P 
Sbjct: 1309 GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1368

Query: 307  FCPHYEKVSGDYGHPVYIVQDGP--PQSPPNI 336
                     G+ G P    QDGP  P  PP +
Sbjct: 1369 GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1400



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 46/176 (26%), Positives = 56/176 (31%), Gaps = 30/176 (17%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATS-----RGAEGPLPPP 223
            Q P G   P+ P   +      G     EPG+   PG P           RG +G   PP
Sbjct: 1191 QGPNGADGPQGPPGSVGSVG--GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248

Query: 224  SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGG 282
                  GA G          G  G       +  P     PG PG  G  G  G  G GG
Sbjct: 1249 GAAGPPGAKGP--------PGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1294

Query: 283  MGPREAEPGELGIALRGG--------GAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
                + +PG+ G     G        G   PP     E   G+ G       +GPP
Sbjct: 1295 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1350



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/165 (29%), Positives = 61/165 (36%), Gaps = 25/165 (15%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G   P+ P  +   E  RG    +  G++ LPG     A   G  GP+ PP +P + G  
Sbjct: 1354 GPVGPQGPAGKPGPEGLRGIPGPV--GEQGLPGA----AGQDGPPGPMGPPGLPGLKGDP 1407

Query: 233  GGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREA 288
            G         L+G+ G  G    +  R  P       PG+ G GG  G  G  G      
Sbjct: 1408 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1465

Query: 289  EPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             PG  G     G        P  +K  GD G P      GPP SP
Sbjct: 1466 LPGPQGPKGNKGSTG-----PAGQK--GDSGLP------GPPGSP 1497



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 47/177 (26%), Positives = 63/177 (35%), Gaps = 32/177 (18%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     EPG++   GD       +G  GP  PP +   
Sbjct: 1068 QGPVGLPGPAGPAGSPGEDGDKGEIG--EPGQKGSKGD-------KGENGPPGPPGLQGP 1118

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSF-GRGGSLGLGGGGGMGPRE 287
             GA         G+AG  G    R ++    +    G   F G  G +GL G  G    +
Sbjct: 1119 VGAP--------GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1170

Query: 288  AEPGELG----------IALRGGGAADPPFCPHYEKVS----GDYGHPVYIVQDGPP 330
             E G++G             +G   AD P  P     S    G+ G P      GPP
Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1227



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 40/146 (27%), Positives = 47/146 (32%), Gaps = 34/146 (23%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G + LPG P     + G  GP+ PP  P   G  G       G  G  G           
Sbjct: 1159 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPN-----GADGPQGP---------- 1202

Query: 259  SESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG-----------GAADPPF 307
                   PGS G  G +G  G  G       PGE G+    G           GAA PP 
Sbjct: 1203 -------PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1255

Query: 308  CPHYEKVSGDYGHPVYIVQDGPPQSP 333
                    G  G+P  +   G P  P
Sbjct: 1256 AKGPPGDDGPKGNPGPVGFPGDPGPP 1281



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 41/147 (27%), Positives = 50/147 (34%), Gaps = 27/147 (18%)

Query: 172 RGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGA 231
           RG   P  P  +  M  + G     E G   LPG+    A  RG  GP   P  P   G 
Sbjct: 579 RGPQGPPGPPGDDGMRGEDG-----EIGPRGLPGE----AGPRGLLGPRGTPGAPGQPGM 629

Query: 232 AGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-------------GSFGRGGSLGLG 278
           AG     + G  G  G M  +     P +  +PGP             G  G  G  GL 
Sbjct: 630 AG-----VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 684

Query: 279 GGGGMGPREAEPGELGIALRGGGAADP 305
           G  G       PG+ G +   G    P
Sbjct: 685 GLPGADGPPGHPGKEGQSGEKGALGPP 711



 Score = 29.3 bits (64), Expect = 5.3
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 21/110 (19%)

Query: 199 GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG--GLALLL---LGVAGAGGAMCWRR 253
           G    PGDP       G  GP   P +P   G  G  G  L+L    G  G+ G     +
Sbjct: 421 GPTGPPGDP-------GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 473

Query: 254 --------RRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELG 294
                   ++A+ +    PGP G  GR G +G  G  G      +PG  G
Sbjct: 474 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 523


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 44/137 (32%), Positives = 53/137 (38%), Gaps = 22/137 (16%)

Query: 198  PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
            PGK+ LPG P     + G +G   PP    V G  G       G  G  G          
Sbjct: 939  PGKDGLPGHPGQRGET-GFQGKTGPPGPGGVVGPQGPT-----GETGPIG---------- 982

Query: 258  PSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGD 317
              E  HPGP   G  G  GL G  G    + +PG  GI+ + G A    F P    + G 
Sbjct: 983  --ERGHPGPP--GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGA 1037

Query: 318  YGHPVYIVQDGPPQSPP 334
             G P     +G PQ PP
Sbjct: 1038 QGAPGLKGGEG-PQGPP 1053



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 45/154 (29%), Positives = 60/154 (38%), Gaps = 21/154 (13%)

Query: 183 EMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGV 242
           +M ++ DRG    + P  E+ P  P      +G  GP   P     AG  G      LGV
Sbjct: 791 DMGLKGDRGEVGQIGPRGEDGPEGP------KGRAGPTGDPGPSGQAGEKG-----KLGV 839

Query: 243 AGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGG 301
            G  G   +  R+     +  PG PG+ G  G+ G+ G  G   +    G  G      G
Sbjct: 840 PGLPG---YPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG----SRG 892

Query: 302 AADPPFCPHYEKVSGDYGHPVYIVQDGP--PQSP 333
           A  P   P  +  SG  G P    + GP  PQ P
Sbjct: 893 ARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGP 926



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 53/181 (29%), Positives = 65/181 (35%), Gaps = 22/181 (12%)

Query: 169 QSPRGGAVPRKPVSEMPMERDR-----GAAHSLEPGK------ENLPGDPTSNATSRGAE 217
           Q PRG   P  P  + P +R R     G     EPG       + LPG P      RG  
Sbjct: 561 QGPRGVQGPPGPTGK-PGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKG-HRGER 618

Query: 218 GPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRG 272
           GP  PP  P   G  G    +    L G AG  G +  R     P +    G  G  G  
Sbjct: 619 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPK 678

Query: 273 GSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQS 332
           G++G  G  G   ++  PG  G+     G   P   P  +   G  G       DGPP  
Sbjct: 679 GNMGPQGEPGPPGQQGNPGPQGLP----GPQGPIGPPGEKGPQGKPGLAGLPGADGPPGH 734

Query: 333 P 333
           P
Sbjct: 735 P 735



 Score = 39.3 bits (90), Expect = 0.005
 Identities = 45/152 (29%), Positives = 54/152 (35%), Gaps = 18/152 (11%)

Query: 198  PGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
            PG +  PGD  P  N    G  G   PP  P  AG  G     + G  G  G        
Sbjct: 1293 PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDG-----VGGDKGEDGDPGQPGPP 1347

Query: 256  AKPSESRHPGP-------GSFGRGGSLGLGGGGGMGPREAEPGELG-IALRG-GGAADPP 306
                E+  PGP       G+ G  G  G  G  G    E  PG+ G +  +G  G   P 
Sbjct: 1348 GPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPE 1407

Query: 307  FCPHYEKVSGDYGHPVYIVQDGP--PQSPPNI 336
                     G+ G P    QDGP  P  PP +
Sbjct: 1408 GLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1439



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 46/176 (26%), Positives = 56/176 (31%), Gaps = 30/176 (17%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATS-----RGAEGPLPPP 223
            Q P G   P+ P   +      G     EPG+   PG P           RG +G   PP
Sbjct: 1230 QGPNGADGPQGPPGSVGSVG--GVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287

Query: 224  SMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGG 282
                  GA G          G  G       +  P     PG PG  G  G  G  G GG
Sbjct: 1288 GAAGPPGAKGP--------PGDDGP------KGNPGPVGFPGDPGPPGEPGPAGQDGVGG 1333

Query: 283  MGPREAEPGELGIALRGG--------GAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
                + +PG+ G     G        G   PP     E   G+ G       +GPP
Sbjct: 1334 DKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1389



 Score = 38.1 bits (87), Expect = 0.011
 Identities = 48/165 (29%), Positives = 61/165 (36%), Gaps = 25/165 (15%)

Query: 173  GGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAA 232
            G   P+ P  +   E  RG    +  G++ LPG     A   G  GP+ PP +P + G  
Sbjct: 1393 GPVGPQGPAGKPGPEGLRGIPGPV--GEQGLPGA----AGQDGPPGPMGPPGLPGLKGDP 1446

Query: 233  GGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREA 288
            G         L+G+ G  G    +  R  P       PG+ G GG  G  G  G      
Sbjct: 1447 GSKGEKGHPGLIGLIGPPGEQGEKGDRGLP--GTQGSPGAKGDGGIPGPAGPLGPPGPPG 1504

Query: 289  EPGELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             PG  G     G        P  +K  GD G P      GPP SP
Sbjct: 1505 LPGPQGPKGNKGSTG-----PAGQK--GDSGLP------GPPGSP 1536



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 47/177 (26%), Positives = 63/177 (35%), Gaps = 32/177 (18%)

Query: 169  QSPRGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAV 228
            Q P G   P  P      + D+G     EPG++   GD       +G  GP  PP +   
Sbjct: 1107 QGPVGLPGPAGPAGSPGEDGDKGEIG--EPGQKGSKGD-------KGENGPPGPPGLQGP 1157

Query: 229  AGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGPGSF-GRGGSLGLGGGGGMGPRE 287
             GA         G+AG  G    R ++    +    G   F G  G +GL G  G    +
Sbjct: 1158 VGAP--------GIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEK 1209

Query: 288  AEPGELG----------IALRGGGAADPPFCPHYEKVS----GDYGHPVYIVQDGPP 330
             E G++G             +G   AD P  P     S    G+ G P      GPP
Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPP 1266



 Score = 37.0 bits (84), Expect = 0.025
 Identities = 40/146 (27%), Positives = 47/146 (32%), Gaps = 34/146 (23%)

Query: 199  GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
            G + LPG P     + G  GP+ PP  P   G  G       G  G  G           
Sbjct: 1198 GLQGLPGPPGEKGEN-GDVGPMGPPGPPGPRGPQGPN-----GADGPQGP---------- 1241

Query: 259  SESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG-----------GAADPPF 307
                   PGS G  G +G  G  G       PGE G+    G           GAA PP 
Sbjct: 1242 -------PGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPG 1294

Query: 308  CPHYEKVSGDYGHPVYIVQDGPPQSP 333
                    G  G+P  +   G P  P
Sbjct: 1295 AKGPPGDDGPKGNPGPVGFPGDPGPP 1320



 Score = 35.8 bits (81), Expect = 0.056
 Identities = 41/147 (27%), Positives = 50/147 (34%), Gaps = 27/147 (18%)

Query: 172 RGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGA 231
           RG   P  P  +  M  + G     E G   LPG+    A  RG  GP   P  P   G 
Sbjct: 618 RGPQGPPGPPGDDGMRGEDG-----EIGPRGLPGE----AGPRGLLGPRGTPGAPGQPGM 668

Query: 232 AGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-------------GSFGRGGSLGLG 278
           AG     + G  G  G M  +     P +  +PGP             G  G  G  GL 
Sbjct: 669 AG-----VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLA 723

Query: 279 GGGGMGPREAEPGELGIALRGGGAADP 305
           G  G       PG+ G +   G    P
Sbjct: 724 GLPGADGPPGHPGKEGQSGEKGALGPP 750



 Score = 29.3 bits (64), Expect = 5.3
 Identities = 32/110 (29%), Positives = 42/110 (38%), Gaps = 21/110 (19%)

Query: 199 GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG--GLALLL---LGVAGAGGAMCWRR 253
           G    PGDP       G  GP   P +P   G  G  G  L+L    G  G+ G     +
Sbjct: 460 GPTGPPGDP-------GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQ 512

Query: 254 --------RRAKPSESRHPGP-GSFGRGGSLGLGGGGGMGPREAEPGELG 294
                   ++A+ +    PGP G  GR G +G  G  G      +PG  G
Sbjct: 513 EAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 562


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 45.1 bits (105), Expect = 9e-05
 Identities = 47/169 (27%), Positives = 58/169 (34%), Gaps = 36/169 (21%)

Query: 171  PRGGAVPRKPVSEMPMERDRGAAHSLE----PGKENLPGDPTSNAT--------SRGAEG 218
            P GG+ P  P     ++ +RG+         PG   LPG P SN          S G +G
Sbjct: 844  PPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDG 903

Query: 219  PLPP------PSMPAVAGAAGGL----------------ALLLLGVAGAGGAMCWRRRRA 256
            P  P      P  P V+G  G                  A   LG+AG  GA        
Sbjct: 904  PPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPG 963

Query: 257  KPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADP 305
             P     PGP   G  G  G  G  G+      PG  G+    G A +P
Sbjct: 964  MPGPRGSPGPQ--GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEP 1010



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 47/149 (31%), Positives = 58/149 (38%), Gaps = 14/149 (9%)

Query: 198  PGKENLPGD--PTSNATSRGAEGPLPPPSMPAVAGAAGGLALL----LLGVAGAGGAMCW 251
            PG    PG   P   +  RG  GP  P   P  AG+ G           G  G  GA   
Sbjct: 1046 PGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI 1105

Query: 252  RRRRAKPSESRHPG-PGSFGRGGSLGLGGGGG----MGPREAEPGELGIALRGGGAADP- 305
            +  R  P     PG PG  G+ G++G  G  G    +GP    PG+ G +   G    P 
Sbjct: 1106 KGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGP-SGPPGKDGTSGHPGPIGPPG 1164

Query: 306  PFCPHYEKVS-GDYGHPVYIVQDGPPQSP 333
            P     E+ S G  GHP      GPP +P
Sbjct: 1165 PRGNRGERGSEGSPGHPGQPGPPGPPGAP 1193



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 53/174 (30%), Positives = 65/174 (37%), Gaps = 36/174 (20%)

Query: 186 MERDRGAAHSLEP-GKENLPGDPTSNATS-----RGAEGPLPPPSMPAVAGAAG-GLALL 238
           M  +RG   S  P G +  PG P ++        RG  GP+ PP      G  G G A  
Sbjct: 727 MPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPG 786

Query: 239 LLGVAGAGGAMCWRRRRAKPSESRHPG----------------PGSFGRGGSLGLGG-GG 281
           L G+AG  G+   R     P  +  PG                PG  G GG  G+ G  G
Sbjct: 787 LPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG 846

Query: 282 GMGPREAEPGELGI-----ALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           G GP    PG  G+     +  G GAA  P         G  G+P      GPP
Sbjct: 847 GSGP-AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNP------GPP 893



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/128 (32%), Positives = 47/128 (36%), Gaps = 23/128 (17%)

Query: 199 GKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKP 258
           G+  LPG+        GA GP+ P   P   G  G     L G AGA G    R    +P
Sbjct: 285 GENGLPGE-------NGAPGPMGPRGAPGERGRPG-----LPGAAGARGNDGARGSDGQP 332

Query: 259 SESRHPG-------PGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHY 311
                PG       PG+ G  G  G  G  G   +  EPG  G A    GA  PP  P  
Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA----GAQGPPGPPGI 388

Query: 312 EKVSGDYG 319
               G  G
Sbjct: 389 NGSPGGKG 396



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 49/171 (28%), Positives = 58/171 (33%), Gaps = 27/171 (15%)

Query: 185 PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAG----------- 233
           P  +D  +     PG+  LPG P       G +GP   P  P + G  G           
Sbjct: 226 PAGKDGESGRPGRPGERGLPGPP-------GIKGPAGIPGFPGMKGHRGFDGRNGEKGET 278

Query: 234 GLALLL--LGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGGGMGPREAEP 290
           G   L    G+ G  GA      R  P E   PG PG+ G  G+ G  G  G       P
Sbjct: 279 GAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338

Query: 291 GELGIALRGG--GAADPPFCPHYEKVSGDYGHP---VYIVQDGPPQSPPNI 336
           G  G     G  G   P   P      G  G P    +    GPP  PP I
Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPP-GPPGI 388



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 18/132 (13%)

Query: 199 GKENLPGDPTSNAT--SRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRA 256
           G +  PG P  N +   +G  GP   P  P + GA G       G AGA GA   R    
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPP-----GPAGANGAPGLRGGAG 432

Query: 257 KPSESR---HPGP-GSFGRGGSLGLGGGGGMGPREA---EPGELGIALRGGGAADPPFCP 309
           +P ++     PGP G  G  G  G+ G  G   ++    EPG  G+     GAA     P
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP----GAAGERGAP 488

Query: 310 HYEKVSGDYGHP 321
            +   +G  G P
Sbjct: 489 GFRGPAGPNGIP 500



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 45/150 (30%), Positives = 54/150 (36%), Gaps = 23/150 (15%)

Query: 197 EPGKENLPGDPTSN-----ATSRGA---EGPLPPPSMPAVAGAAGGLALLLLGVAGAGGA 248
           E GK+  PG+P +N     A  RGA    GP  P  +P   G AG       G  G  G 
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER-----GAPGPAGP 517

Query: 249 MCWRRRRAKPSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRGG-----GAA 303
                R A     R   PG  G  G  G  GG G   +   PG  G + R G     G  
Sbjct: 518 -----RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPR 572

Query: 304 DPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
             P    +    G+ G P    + G P  P
Sbjct: 573 GQPGVMGFPGPKGNDGAPGKNGERGGPGGP 602



 Score = 41.6 bits (96), Expect = 0.001
 Identities = 53/174 (30%), Positives = 59/174 (33%), Gaps = 33/174 (18%)

Query: 171 PRGGAVPRKPVSEM----PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMP 226
           P G + PR     M    P   D     + E G    PG P       G  GP  PP   
Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG-PQGPPGKNGETGPQGPPGPT 623

Query: 227 AVAGAAGGLALL----LLGVAGAGGAMCWRRRRAKPSESRHPG-PGSFGRGGSLGLGGGG 281
              G  G         L G+ G GG          P E+  PG PG  G  G+ G  GG 
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGP---------PGENGKPGEPGPKGDAGAPGAPGGK 674

Query: 282 GMGPREAEPGELGIA----LRGG----------GAADPPFCPHYEKVSGDYGHP 321
           G      E G  G+A    LRGG          GAA PP  P      G  G P
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMP 728



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 42/125 (33%), Positives = 52/125 (41%), Gaps = 20/125 (16%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG+   PG P  +A   GA+GP  PP +    G  G +     G+ GA G M        
Sbjct: 365 PGQRGEPG-PQGHA---GAQGPPGPPGINGSPGGKGEMGPA--GIPGAPGLM-------- 410

Query: 258 PSESRHPGPGSFGRGGSLGLGGGGGMGPREAEPGELGIALRG-GGAADPPFCPHYEKVSG 316
              +R P PG  G  G+ GL GG G   +    GE G   RG  G A  P  P  +   G
Sbjct: 411 --GARGP-PGPAGANGAPGLRGGAGEPGKNGAKGEPG--PRGERGEAGIPGVPGAKGEDG 465

Query: 317 DYGHP 321
             G P
Sbjct: 466 KDGSP 470



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/160 (28%), Positives = 52/160 (32%), Gaps = 42/160 (26%)

Query: 198 PGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAK 257
           PG +  PG+P       G  GP  PP  P   G +G       G  G  G      R  +
Sbjct: 197 PGYQGPPGEP-------GQAGPSGPPGPPGAIGPSGPA-----GKDGESG------RPGR 238

Query: 258 PSESRHPGP-------------------GSFGRGGSLGLGGGGGMGPREAEPGELG---- 294
           P E   PGP                   G  GR G  G  G  G+      PGE G    
Sbjct: 239 PGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGP 298

Query: 295 IALRGG-GAADPPFCPHYEKVSGDYGHPVYIVQDGPPQSP 333
           +  RG  G    P  P      G+ G      Q GPP  P
Sbjct: 299 MGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPP 338



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 45/143 (31%), Positives = 52/143 (36%), Gaps = 32/143 (22%)

Query: 172  RGGAVPRKPVSEMPMERDRGAA----HSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPA 227
            RG   P+ P  +     +RGAA    H   PG    PG P   A  +GA G       P 
Sbjct: 1082 RGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSP-GPAGQQGAIGS------PG 1134

Query: 228  VAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-------GSFGRGGSLGLGGG 280
             AG  G +     G +G  G         K   S HPGP       G+ G  GS G  G 
Sbjct: 1135 PAGPRGPV-----GPSGPPG---------KDGTSGHPGPIGPPGPRGNRGERGSEGSPGH 1180

Query: 281  GGMGPREAEPGELGIALRGGGAA 303
             G       PG  G    G GAA
Sbjct: 1181 PGQPGPPGPPGAPGPCCGGVGAA 1203



 Score = 37.4 bits (85), Expect = 0.019
 Identities = 44/144 (30%), Positives = 50/144 (34%), Gaps = 34/144 (23%)

Query: 198  PGKENLPG--DPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
            PG +  PG   P   A   GA G   PP MP   G+ G   +   G +G  GA      R
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVK--GESGKPGANGLSGER 992

Query: 256  AKPSESRHPG-------PGSFGRGGSLGL----GGGGGMGPR--------------EAEP 290
              P     PG       PG  G  GS GL    G  GG G R                 P
Sbjct: 993  GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 291  GELGIALRGG-----GAADPPFCP 309
            G +G A + G     G A P   P
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAP 1076



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 37/140 (26%), Positives = 46/140 (32%), Gaps = 35/140 (25%)

Query: 204 PGDPTSNATSRGAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRH 263
           P  PT     +G +GP   P  P + G  G       G+ G                   
Sbjct: 92  PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGD-----PGIPGQ------------------ 128

Query: 264 PGPGSFGRGGSLGLGGGGGMGPREAEPG------ELGIALRG----GGAADPPFCPHYEK 313
             PGS G  G  G+      GP+   P       + G+A+ G     G A PP  P    
Sbjct: 129 --PGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPG 186

Query: 314 VSGDYGHPVYIVQDGPPQSP 333
            SG  G P      GPP  P
Sbjct: 187 TSGHPGSPGSPGYQGPPGEP 206



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 10/106 (9%)

Query: 215 GAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP-GSFGRGG 273
           G  GP  PP  P   G +G          G+ G+  ++    +P ++   GP G  G  G
Sbjct: 171 GYPGPAGPPGPPGPPGTSGH--------PGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222

Query: 274 SLGLGGGGGMGPREAEPGELGIALRGGGAADPPFCPHYEKVSGDYG 319
             G  G  G   R   PGE G+     G   P   P +  + G  G
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLP-GPPGIKGPAGIPGFPGMKGHRG 267



 Score = 32.7 bits (73), Expect = 0.48
 Identities = 47/160 (29%), Positives = 50/160 (31%), Gaps = 45/160 (28%)

Query: 198 PGKENLPGDPTSNATSR--GAEGPLPPPSMPAVAGAAGGLALLLLGVAGAGGAMCWRRRR 255
           PG +  PG P S   S   G  GP  P   P V G  G       G  GA G    R   
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPK-----GNDGAPGKNGERGGP 599

Query: 256 AKPSESRHPG----------PGSFGRGGSLG---------------LGGGGGMGPREAEP 290
             P     PG          PG  G GG  G                GG  G   +  EP
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659

Query: 291 GELGIALRGGGAADPPFCPHYEKVSGDYGHPVYIVQDGPP 330
           G  G A    GA   P         GD G P    + GPP
Sbjct: 660 GPKGDA----GAPGAP------GGKGDAGAP---GERGPP 686



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 52/165 (31%), Positives = 56/165 (33%), Gaps = 26/165 (15%)

Query: 172 RGGAVPRKPVSEMPMERDRGAAHSLEPGKENLPGDPTSNATSRGAEGPLPPPSMPAVAGA 231
           RGGA P  P      E  +GAA    PG     G P       G  G L  P      G 
Sbjct: 695 RGGAGPPGP------EGGKGAAGP--PGPPGAAGTPGLQGMP-GERGGLGSPGPKGDKGE 745

Query: 232 AGGLALLLLGVAGAGGAMCWRRRRAKPSESRHPGP----GSFGRGGSLGLGGGGGMGPRE 287
            GG         GA G       R        PGP    G  G GG+ GL G    GPR 
Sbjct: 746 PGG--------PGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA--GPR- 794

Query: 288 AEPGELGIALRGGGAADP--PFCPHYEKVSGDYGHPVYIVQDGPP 330
             PGE G     G A  P  P         G+ G P    + GPP
Sbjct: 795 GSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839



 Score = 32.3 bits (72), Expect = 0.62
 Identities = 29/86 (33%), Positives = 35/86 (40%), Gaps = 15/86 (17%)

Query: 173  GGAVPRKPVSEM-PMERDRGAAHSLEPGKENLPGDPTSNATSRGAEG----------PLP 221
            G A PR PV    P  +D  + H   PG    PG P  N   RG+EG          P P
Sbjct: 1134 GPAGPRGPVGPSGPPGKDGTSGH---PGPIGPPG-PRGNRGERGSEGSPGHPGQPGPPGP 1189

Query: 222  PPSMPAVAGAAGGLALLLLGVAGAGG 247
            P +     G  G  A+  +G   AGG
Sbjct: 1190 PGAPGPCCGGVGAAAIAGIGGEKAGG 1215


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.142    0.452 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,022,149
Number of Sequences: 37866
Number of extensions: 1153560
Number of successful extensions: 9899
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 117
Number of HSP's successfully gapped in prelim test: 512
Number of HSP's that attempted gapping in prelim test: 6390
Number of HSP's gapped (non-prelim): 2421
length of query: 340
length of database: 18,247,518
effective HSP length: 103
effective length of query: 237
effective length of database: 14,347,320
effective search space: 3400314840
effective search space used: 3400314840
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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