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Search of human proteins with 4503449
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens]
(391 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens] 812 0.0
gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens] 804 0.0
gi|54112103 ectodysplasin A isoform EDA-B [Homo sapiens] 346 2e-95
gi|54112105 ectodysplasin A isoform EDA-C [Homo sapiens] 275 5e-74
gi|54112113 ectodysplasin A isoform EDA-O [Homo sapiens] 274 1e-73
gi|54112107 ectodysplasin A isoform EDA-D [Homo sapiens] 274 1e-73
gi|18641360 collectin sub-family member 12 [Homo sapiens] 96 6e-20
gi|119829187 alpha 1 type XVII collagen [Homo sapiens] 96 6e-20
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 94 2e-19
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 93 5e-19
gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo... 92 8e-19
gi|48762934 alpha 2 type I collagen [Homo sapiens] 92 1e-18
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 89 5e-18
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 89 5e-18
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 89 5e-18
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 89 5e-18
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 89 5e-18
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 89 9e-18
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 89 9e-18
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 89 9e-18
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 89 9e-18
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 89 9e-18
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 89 9e-18
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 89 9e-18
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 88 2e-17
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 88 2e-17
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 87 2e-17
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 87 2e-17
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 87 3e-17
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 87 3e-17
>gi|4503449 ectodysplasin A isoform EDA-A1 [Homo sapiens]
Length = 391
Score = 812 bits (2098), Expect = 0.0
Identities = 391/391 (100%), Positives = 391/391 (100%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG 180
AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG
Sbjct: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG 180
Query: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK
Sbjct: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK 240
Query: 241 AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT 300
AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT
Sbjct: 241 AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT 300
Query: 301 YFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI 360
YFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI
Sbjct: 301 YFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI 360
Query: 361 AVKMVHADISINMSKHTTFFGAIRLGEAPAS 391
AVKMVHADISINMSKHTTFFGAIRLGEAPAS
Sbjct: 361 AVKMVHADISINMSKHTTFFGAIRLGEAPAS 391
>gi|54112101 ectodysplasin A isoform EDA-A2 [Homo sapiens]
Length = 389
Score = 804 bits (2076), Expect = 0.0
Identities = 389/391 (99%), Positives = 389/391 (99%), Gaps = 2/391 (0%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG 180
AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG
Sbjct: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAG 180
Query: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK
Sbjct: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADK 240
Query: 241 AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT 300
AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT
Sbjct: 241 AGTRENQPAVVHLQGQGSAIQVKNDLSGGVLNDWSRITMNPKVFKLHPRSGELEVLVDGT 300
Query: 301 YFIYSQVEVYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI 360
YFIYSQ VYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI
Sbjct: 301 YFIYSQ--VYYINFTDFASYEVVVDEKPFLQCTRSIETGKTNYNTCYTAGVCLLKARQKI 358
Query: 361 AVKMVHADISINMSKHTTFFGAIRLGEAPAS 391
AVKMVHADISINMSKHTTFFGAIRLGEAPAS
Sbjct: 359 AVKMVHADISINMSKHTTFFGAIRLGEAPAS 389
>gi|54112103 ectodysplasin A isoform EDA-B [Homo sapiens]
Length = 178
Score = 346 bits (887), Expect = 2e-95
Identities = 168/168 (100%), Positives = 168/168 (100%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG 168
AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG
Sbjct: 121 AALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG 168
>gi|54112105 ectodysplasin A isoform EDA-C [Homo sapiens]
Length = 147
Score = 275 bits (703), Expect = 5e-74
Identities = 133/136 (97%), Positives = 135/136 (99%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQMALL 136
AALHSDSQDGHQ++ L
Sbjct: 121 AALHSDSQDGHQVSHL 136
>gi|54112113 ectodysplasin A isoform EDA-O [Homo sapiens]
Length = 135
Score = 274 bits (700), Expect = 1e-73
Identities = 132/132 (100%), Positives = 132/132 (100%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQ 132
AALHSDSQDGHQ
Sbjct: 121 AALHSDSQDGHQ 132
>gi|54112107 ectodysplasin A isoform EDA-D [Homo sapiens]
Length = 142
Score = 274 bits (700), Expect = 1e-73
Identities = 132/132 (100%), Positives = 132/132 (100%)
Query: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC
Sbjct: 1 MGYPEVERRELLPAAAPRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCC 60
Query: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE
Sbjct: 61 YLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
Query: 121 AALHSDSQDGHQ 132
AALHSDSQDGHQ
Sbjct: 121 AALHSDSQDGHQ 132
>gi|18641360 collectin sub-family member 12 [Homo sapiens]
Length = 742
Score = 95.9 bits (237), Expect = 6e-20
Identities = 63/166 (37%), Positives = 73/166 (43%), Gaps = 30/166 (18%)
Query: 82 GTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFP 141
G PG G G P P T + GQ K +P PG A
Sbjct: 443 GPPGPRGPRGDRGSQGPPGP-TGNKGQKGEKGEPGPPGPAG------------------- 482
Query: 142 DEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGP---PGPQG 198
+ P R K SK ++G G + K GP G GPPGPPG PGPQG
Sbjct: 483 ERGPIGPAGPPGERGGKGSKGSQGPKGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQG 542
Query: 199 PPGIPGI------PGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGA 237
PPG G+ PG+PG + G PG PG PGP+GPPG GPSGA
Sbjct: 543 PPGFQGLQGTVGEPGVPGPRGLPGLPGVPGMPGPKGPPGPPGPSGA 588
Score = 81.3 bits (199), Expect = 1e-15
Identities = 48/105 (45%), Positives = 55/105 (52%), Gaps = 16/105 (15%)
Query: 155 RRNKRSKSNEGADGPVKNK-KKGKKA--GPPGPNGPPGPPGPPGP------------QGP 199
R + + ++G GP NK +KG+K GPPGP G GP GP GP QGP
Sbjct: 448 RGPRGDRGSQGPPGPTGNKGQKGEKGEPGPPGPAGERGPIGPAGPPGERGGKGSKGSQGP 507
Query: 200 PGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
G G PG PG G PGPPGPPG +G PG QGP G GT
Sbjct: 508 KGSRGSPGKPGPQGPSGDPGPPGPPGKEGLPGPQGPPGFQGLQGT 552
Score = 63.5 bits (153), Expect = 3e-10
Identities = 32/68 (47%), Positives = 36/68 (52%), Gaps = 5/68 (7%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
GPPGP GP G G GP GP G G G G PGPPGP G +GP G GP G
Sbjct: 443 GPPGPRGPRGDRGSQGPPGPTGNKGQKG-----EKGEPGPPGPAGERGPIGPAGPPGERG 497
Query: 240 KAGTRENQ 247
G++ +Q
Sbjct: 498 GKGSKGSQ 505
Score = 36.2 bits (82), Expect = 0.052
Identities = 15/34 (44%), Positives = 20/34 (58%)
Query: 211 TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
T + GPPGP GP G +G G GP+G + G +
Sbjct: 439 TILQGPPGPRGPRGDRGSQGPPGPTGNKGQKGEK 472
>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
Length = 1497
Score = 95.9 bits (237), Expect = 6e-20
Identities = 70/196 (35%), Positives = 84/196 (42%), Gaps = 38/196 (19%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP--ITSHLGQPSPKQQPLEPGEAALHSD 126
R E+G G G PG SG G P P + G+P K +P PG+
Sbjct: 754 RGEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEG 813
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV---------KNKKKGK 177
S ++L P P + GA GP +
Sbjct: 814 S------SMLTVPGPPGPPGA----------MGPPGPPGAPGPAGPAGLPGHQEVLNLQG 857
Query: 178 KAGPPGPNGPPGP--PGPPGPQGPP--GIPGIPGIPG-------TTVMGPPGPPGPPGPQ 226
GPPGP GPPGP PGPPGP+GPP G+PG PG PG T + GPPGPPGPPGP+
Sbjct: 858 PPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETFLSGPPGPPGPPGPK 917
Query: 227 GPPGLQGPSGAADKAG 242
G G GP G + G
Sbjct: 918 GDQGPPGPRGHQGEQG 933
Score = 92.4 bits (228), Expect = 6e-19
Identities = 75/226 (33%), Positives = 89/226 (39%), Gaps = 54/226 (23%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERGA G G PG G++ G P G P P GE L D
Sbjct: 645 ERGAAGEPGPHGPPGVPGSVGPKGSSGSPGP----QGPPGPVGLQGLRGEVGLPGVKGDK 700
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSN----------EGADGPV----KNKKKG 176
M P K E+ R + +GA GP +G
Sbjct: 701 GPMGP-----PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRG 755
Query: 177 KKA--------GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGT----------------- 211
++ GPPGP+G PG PG GPQGP G+PG PG PG
Sbjct: 756 EQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSS 815
Query: 212 --TVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
TV GPPGPPG GP GPPG GP+G A G +E V++LQG
Sbjct: 816 MLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQE----VLNLQG 857
Score = 85.1 bits (209), Expect = 1e-16
Identities = 65/184 (35%), Positives = 74/184 (40%), Gaps = 29/184 (15%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG G G PG G + G + P P H G + PG S D
Sbjct: 718 RGLTGEPGMRGLPGAVGEPGAKGAMGPAGP-DGHQGPRGEQGLTGMPGIRGPPGPSGDPG 776
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKA------GPPGPN 185
+ L P P + K GA G + + GPPG
Sbjct: 777 KPGLTGPQGPQGLPGTPGRPG-------IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAM 829
Query: 186 GPPGPPGPPGPQGPPGIPGI---------PGIPGTTVMGPPGP--PGPPGPQGPP--GLQ 232
GPPGPPG PGP GP G+PG PG PG GPPGP PGPPGP+GPP GL
Sbjct: 830 GPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPR--GPPGPSIPGPPGPRGPPGEGLP 887
Query: 233 GPSG 236
GP G
Sbjct: 888 GPPG 891
Score = 82.8 bits (203), Expect = 5e-16
Identities = 66/192 (34%), Positives = 76/192 (39%), Gaps = 29/192 (15%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLD------PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
G R G G PG G + + G P P +G P P P G A L
Sbjct: 791 GTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP-PGAMGPPGPPGAPGPAGPAGL--- 846
Query: 127 SQDGHQMALLNFFFPDEKPYSEEE---SRRVRRNKRSKSNEGADGP------VKNKKKGK 177
GHQ +LN P P S R EG GP + +
Sbjct: 847 --PGHQ-EVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNSETF 903
Query: 178 KAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGP-------PGPPGPPGPQGPPG 230
+GPPGP GPPGP G GP GP G G G+PG + G GPPGPPGPQGP G
Sbjct: 904 LSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQGPKG 963
Query: 231 LQGPSGAADKAG 242
+G G G
Sbjct: 964 DKGDPGVPGALG 975
Score = 79.3 bits (194), Expect = 5e-15
Identities = 58/183 (31%), Positives = 73/183 (39%), Gaps = 11/183 (6%)
Query: 62 LELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEA 121
L + E RG+ G G+PG G G P+ H G PK Q G+
Sbjct: 556 LMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIPGPL-GHPGPQGPKGQKGSVGDP 614
Query: 122 ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ + + P S E+ R G GP GP
Sbjct: 615 GMEGPMGQRGREGPMGPRGEAGPPGSGEKGER--------GAAGEPGPHGPPGVPGSVGP 666
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
G +G PGP GPPGP G G+ G G+PG V G GP GPPGP+G G +GP G +
Sbjct: 667 KGSSGSPGPQGPPGPVGLQGLRGEVGLPG--VKGDKGPMGPPGPKGDQGEKGPRGLTGEP 724
Query: 242 GTR 244
G R
Sbjct: 725 GMR 727
Score = 74.7 bits (182), Expect = 1e-13
Identities = 54/154 (35%), Positives = 69/154 (44%), Gaps = 28/154 (18%)
Query: 123 LHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPP 182
LHSDSQ+ M F +K E+E+ +R + K + G+ GP ++ G P
Sbjct: 540 LHSDSQEELWM------FVRKKLMMEQENGNLRGSPGPKGDMGSPGPKGDRGFPGTPGIP 593
Query: 183 GPNGPPGPPGPPGPQGPPGIPGIPGIPGTT----------VMGPPGP-----------PG 221
GP G PGP GP G +G G PG+ G G GPPG PG
Sbjct: 594 GPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRGEAGPPGSGEKGERGAAGEPG 653
Query: 222 PPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
P GP G PG GP G++ G + P V LQG
Sbjct: 654 PHGPPGVPGSVGPKGSSGSPGP-QGPPGPVGLQG 686
Score = 72.4 bits (176), Expect = 7e-13
Identities = 56/177 (31%), Positives = 70/177 (39%), Gaps = 14/177 (7%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPI----TSHLGQPSPKQQPLE--PGEAALHSD 126
GA G +G PG L+ G P P S G P P+ P E PG
Sbjct: 836 GAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGS 895
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P P + + + + +G G + GP G
Sbjct: 896 FLSNSETFLSGPPGPPGPP-GPKGDQGPPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954
Query: 187 PPGPPGPPGPQGPPGIPGIPGIP-------GTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PPGP GP G +G PG+PG GIP ++ M GPPGPPGP GPPG SG
Sbjct: 955 PPGPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPPGSISSSG 1011
Score = 71.2 bits (173), Expect = 1e-12
Identities = 39/92 (42%), Positives = 42/92 (45%), Gaps = 34/92 (36%)
Query: 176 GKKAGPPGPNGPPGPPGPP--------------GPQGPPGIPGIPGIPGTT--------- 212
G G PGP GPPG PG G GPPG PG PGIPG
Sbjct: 1142 GISIGLPGPPGPPGLPGTSYEELLSLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDL 1201
Query: 213 -----------VMGPPGPPGPPGPQGPPGLQG 233
+ GPPGPPGPPGP+GPPG+ G
Sbjct: 1202 SSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSG 1233
Score = 69.3 bits (168), Expect = 6e-12
Identities = 60/192 (31%), Positives = 78/192 (40%), Gaps = 24/192 (12%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSP--------KQQPLEP-G 119
+ G+ G G PGT G LG P P +G P ++ P+ P G
Sbjct: 574 DMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRG 633
Query: 120 EAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKA 179
EA + G + A P S + + S +G GPV + +
Sbjct: 634 EAGPPGSGEKGERGAAGEP--GPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEV 691
Query: 180 GPPG------PNGPPGPPGPPGPQGPPGI---PGIPGIPGTTVMGPPGPPGPPGPQGPPG 230
G PG P GPPGP G G +GP G+ PG+ G+PG +G PG G GP GP G
Sbjct: 692 GLPGVKGDKGPMGPPGPKGDQGEKGPRGLTGEPGMRGLPG--AVGEPGAKGAMGPAGPDG 749
Query: 231 LQGPSGAADKAG 242
QGP G G
Sbjct: 750 HQGPRGEQGLTG 761
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/100 (37%), Positives = 40/100 (40%), Gaps = 49/100 (49%)
Query: 180 GPPGPNGPPG----------------------------PPGPPGPQGPPGIPGIPGIPGT 211
GPPGP GPPG PPGPPGP GP G PG+ G T
Sbjct: 1178 GPPGPPGPPGIPGNVWSSISVEDLSSYLHTAGLSFIPGPPGPPGPPGPRGPPGVSGALAT 1237
Query: 212 --------------TVMGPP-------GPPGPPGPQGPPG 230
+ + P GPPGPPGPQGPPG
Sbjct: 1238 YAAENSDSFRSELISYLTSPDVRSFIVGPPGPPGPQGPPG 1277
Score = 60.8 bits (146), Expect = 2e-09
Identities = 57/200 (28%), Positives = 71/200 (35%), Gaps = 47/200 (23%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
GG+G+ G G G P + +G E G A + LL
Sbjct: 1316 GGAGSLGAGGAFGEAAG--DRGPYGTDIGPGGGYGAAAEGGMYAGNG--------GLLGA 1365
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP------- 191
F + Y+E R +R +G V+ GPPG GP GPP
Sbjct: 1366 DFAGDLDYNELAVRVSESMQRQGLLQGMAYTVQ--------GPPGQPGPQGPPGISKVFS 1417
Query: 192 --------------------GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGL 231
GPPG +G G PG G G GPPG PGPPGP+G G
Sbjct: 1418 AYSNVTADLMDFFQTYGAIQGPPGQKGEMGTPGPKGDRGPA--GPPGHPGPPGPRGHKGE 1475
Query: 232 QGPSGAADKAGTRENQPAVV 251
+G G AG R + V
Sbjct: 1476 KGDKGDQVYAGRRRRRSIAV 1495
Score = 56.6 bits (135), Expect = 4e-08
Identities = 56/169 (33%), Positives = 66/169 (39%), Gaps = 32/169 (18%)
Query: 79 GGSGTPGT--SGTLSSLGGLDPDSPITSHLGQPSPK--QQPLEP----GEAALHSDSQDG 130
G G PG+ S + + L G P P G P PK Q P P GE L S G
Sbjct: 888 GPPGPPGSFLSNSETFLSG-PPGPP-----GPPGPKGDQGPPGPRGHQGEQGLPGFSTSG 941
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
LN P P + + +K GA G +G + +GPPGP
Sbjct: 942 SSSFGLNLQGPPGPPGPQGP----KGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGP 997
Query: 191 PGPPGPQGPPGIPG------------IPGIPG--TTVMGPPGPPGPPGP 225
PGPPGP G G I + V GPPGPPGPPGP
Sbjct: 998 PGPPGPPGSISSSGQEIQQYISEYMQSDSIRSYLSGVQGPPGPPGPPGP 1046
Score = 43.9 bits (102), Expect = 3e-04
Identities = 32/104 (30%), Positives = 41/104 (39%), Gaps = 31/104 (29%)
Query: 183 GPNGPPGPPGPPGPQ-------------------------GPPGIPGIPGIPGTT----- 212
GP GPPGPPG G G PG PG PG+PGT+
Sbjct: 1106 GPRGPPGPPGASGDGSLLSLDYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEELL 1165
Query: 213 -VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
++ G GP GPPG G G + + E+ + +H G
Sbjct: 1166 SLLRGSEFRGIVGPPGPPGPPGIPGNVWSSISVEDLSSYLHTAG 1209
>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
Length = 1142
Score = 94.4 bits (233), Expect = 2e-19
Identities = 62/182 (34%), Positives = 86/182 (47%), Gaps = 27/182 (14%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
+RG++ G G PG +G ++G + P S +G P + P PG + +D+
Sbjct: 960 DRGSQ---GERGKPGLTGMKGAIGPMGPPGNKGS-MGSPGHQGPPGSPGIPGIPADAVS- 1014
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSK--SNEGADGPVKNKKKGKKAGPPGPNGPP 188
F + K Y +E R+ + + S + + + GPPG +G P
Sbjct: 1015 ---------FEEIKKYINQEVLRIFEERMAVFLSQLKLPAAMLAAQAYGRPGPPGKDGLP 1065
Query: 189 GPPGPPGPQG---------PPGI--PGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGA 237
GPPG PGPQG PGI PG PG+PGT+ +G PG PG PGPQGPPG G
Sbjct: 1066 GPPGDPGPQGYRGQKGERGEPGIGLPGSPGLPGTSALGLPGSPGAPGPQGPPGPSGRCNP 1125
Query: 238 AD 239
D
Sbjct: 1126 ED 1127
Score = 82.0 bits (201), Expect = 8e-16
Identities = 61/176 (34%), Positives = 72/176 (40%), Gaps = 11/176 (6%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G G +G PG G L GL P +P G P P G+ L D
Sbjct: 629 GRTGAQGPAGEPGIQGP-RGLPGL-PGTP-----GTPGNDGVPGRDGKPGLPGPPGDPIA 681
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ LL K + V K +K EG G + G GP GPPG PG
Sbjct: 682 LPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKGDIGPRGPPGIPG 741
Query: 193 PPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP+G G G PGIPG + G PG PG PGP GPPGL G +G G +
Sbjct: 742 REGPKGSKGERGYPGIPGEKGDEGLQGIPGIPGAPGPTGPPGLMGRTGHPGPTGAK 797
Score = 77.4 bits (189), Expect = 2e-14
Identities = 63/226 (27%), Positives = 83/226 (36%), Gaps = 44/226 (19%)
Query: 54 HLLTLCCYLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQ 113
H + YL + EL+ + G +G PG G+ P K
Sbjct: 267 HASKMSSYLPAKQELKDQCQCIPNKGEAGLPGAPGS-------------------PGQKG 307
Query: 114 QPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVK-- 171
EPGE LH FP +K E + ++ + E D +
Sbjct: 308 HKGEPGENGLHGAPG-----------FPGQKGEQGFEGSKGETGEKGEQGEKGDPALAGL 356
Query: 172 NKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPG------- 224
N + G K G GP+GPPGP G G GPPG P +PG G + GP GPPG G
Sbjct: 357 NGENGLK-GDLGPHGPPGPKGEKGDTGPPGPPALPGSLG--IQGPQGPPGKEGQRGRRGK 413
Query: 225 --PQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSG 268
P G PG GP G G + + +G+ L G
Sbjct: 414 TGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKG 459
Score = 75.5 bits (184), Expect = 8e-14
Identities = 60/210 (28%), Positives = 81/210 (38%), Gaps = 41/210 (19%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
L+ +G E GG+G PG +++ G + P P G+ PK E G + +
Sbjct: 706 LKSNKGEE---GGAGEPGKYDSMARKGDIGPRGP-PGIPGREGPKGSKGERGYPGIPGEK 761
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKR----SKSNEGADGPVK------------ 171
D + P + R +K +G+DGP
Sbjct: 762 GDEGLQGIPGI--PGAPGPTGPPGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPGPPGIPF 819
Query: 172 NKKKGKKA-----------------GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM 214
N++ G + GPPGP G PGP G PG G PG+ G PG+ G
Sbjct: 820 NERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGD--R 877
Query: 215 GPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP GPPG G G PG GP G + G R
Sbjct: 878 GPAGPPGIAGMSGKPGAPGPPGVPGEPGER 907
Score = 72.0 bits (175), Expect = 9e-13
Identities = 55/158 (34%), Positives = 64/158 (40%), Gaps = 26/158 (16%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G G PG G G DP I G P PK + PG++ DG+ A
Sbjct: 546 GEHGIPGKQGIKGEKG--DPGG-IIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGA---- 598
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQG 198
P + R + S + G G G PG G GP G PG QG
Sbjct: 599 ----PGPRGPKGERGLPGVHGSPGDIGPQG----------IGIPGRTGAQGPAGEPGIQG 644
Query: 199 PPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
P G+PG+PG PGT PG G PG G PGL GP G
Sbjct: 645 PRGLPGLPGTPGT-----PGNDGVPGRDGKPGLPGPPG 677
Score = 70.9 bits (172), Expect = 2e-12
Identities = 58/195 (29%), Positives = 74/195 (37%), Gaps = 31/195 (15%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPI-----------TSHLGQPSPKQQPLEPGEA 121
G + G +G PG SLG P P T G+P P P PG
Sbjct: 373 GPKGEKGDTGPPGPPALPGSLGIQGPQGPPGKEGQRGRRGKTGPPGKPGPPGPPGPPGIQ 432
Query: 122 ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+H L ++ D K E E+ ++ +K G G V K + + G
Sbjct: 433 GIHQ--------TLGGYYNKDNKGNDEHEAGGLKGDKGETGLPGFPGSVGPKGQKGEPGE 484
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
P G G G PG G G+ G PG PGPPG G PGL+G G+A
Sbjct: 485 PFTKGEKGDRGEPGVIGSQGVKGE-----------PGDPGPPGLIGSPGLKGQQGSAGSM 533
Query: 242 GTRENQPAVVHLQGQ 256
G R P V L G+
Sbjct: 534 GPR-GPPGDVGLPGE 547
Score = 70.1 bits (170), Expect = 3e-12
Identities = 64/239 (26%), Positives = 94/239 (39%), Gaps = 39/239 (16%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGL-DPDSPITSH----------LGQPSPKQQPLEPGEA 121
G + G +G PG G++ G +P P T +G K +P +PG
Sbjct: 456 GLKGDKGETGLPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIGSQGVKGEPGDPGPP 515
Query: 122 ALHSD----SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE--GADGPVKNKKK 175
L Q G ++ P + E ++ + + + G GP
Sbjct: 516 GLIGSPGLKGQQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGP 575
Query: 176 GKKAGPPGPN--------GPPGPPGPPGPQGPPGIPGIPGIPGTTV---MGPPGPPGPPG 224
+AGPPG + G PG PGP GP+G G+PG+ G PG +G PG G G
Sbjct: 576 KGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQG 635
Query: 225 PQGPPGLQGPSGAADKAGT-----------RENQPAVVHLQGQGSAIQVKNDLSGGVLN 272
P G PG+QGP G GT R+ +P + G A+ + D+ + N
Sbjct: 636 PAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGKPGLPGPPGDPIALPLLGDIGALLKN 694
Score = 67.4 bits (163), Expect = 2e-11
Identities = 65/228 (28%), Positives = 74/228 (32%), Gaps = 67/228 (29%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSP-----ITSHLGQPSPKQQPLEPGEAALHSD------- 126
G G PG G G P P ++ G P P P EPGE D
Sbjct: 860 GAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPGPE 919
Query: 127 ---------SQDGHQMALLNFFFP-DEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKG 176
+DG A P D P E + + ++ S+ G G K
Sbjct: 920 GPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGA- 978
Query: 177 KKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM---------------------- 214
GP GP G G G PG QGPPG PGIPGIP V
Sbjct: 979 --IGPMGPPGNKGSMGSPGHQGPPGSPGIPGIPADAVSFEEIKKYINQEVLRIFEERMAV 1036
Query: 215 --------------------GPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GPPG G PGP G PG QG G + G
Sbjct: 1037 FLSQLKLPAAMLAAQAYGRPGPPGKDGLPGPPGDPGPQGYRGQKGERG 1084
Score = 65.1 bits (157), Expect = 1e-10
Identities = 56/208 (26%), Positives = 79/208 (37%), Gaps = 52/208 (25%)
Query: 71 ERGAESRLGGSGTPGTSGT-------LSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAAL 123
E+G++ G G PG G +SSL + + S+ G P P +PG
Sbjct: 799 EKGSDGPPGKPGPPGPPGIPFNERNGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPG---- 854
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
P E + + + +G GP +G PG
Sbjct: 855 ---------------------PVGEPGAMGLPGLEGFPGVKGDRGPAGPPGIAGMSGKPG 893
Query: 184 PNGPPGPPGPPGPQGP---------------PGIPGIPGIPGTT-VMGPPGPPGPPGPQG 227
GPPG PG PG +GP PGI G GIPG +MG PG GP G +G
Sbjct: 894 APGPPGVPGEPGERGPVGDIGFPGPEGPSGKPGINGKDGIPGAQGIMGKPGDRGPKGERG 953
Query: 228 PPGLQGPSGAADKAGTRENQPAVVHLQG 255
G+ G G+ + G +P + ++G
Sbjct: 954 DQGIPGDRGSQGERG----KPGLTGMKG 977
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 92.8 bits (229), Expect = 5e-19
Identities = 61/175 (34%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
G + +LG G PG G G + P P + G+ + P +PG +
Sbjct: 862 GEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGAN--GEKGGRGTPGKPGPRGQRGPTG--- 916
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P E R + K N G DGP + GP GP G PGP
Sbjct: 917 -------------PRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPK 963
Query: 192 GPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GPPGP G G+PG PG G T GPPGPPG GPQGP G GP G G
Sbjct: 964 GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPG 1018
Score = 92.4 bits (228), Expect = 6e-19
Identities = 63/188 (33%), Positives = 78/188 (41%), Gaps = 4/188 (2%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R E+G G +G PG G G P+ G P P +P G+ D
Sbjct: 1308 RGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPV-GFPGDPGPPGEPGPAGQDGPPGDKG 1366
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
D + P +P + R EG G K + GPPG GP
Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPGK-RGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQ 247
GP G PG GP G+ GIPG G + G PGP GPPGP GPPGL G G + G +
Sbjct: 1426 GPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKG-EKGH 1484
Query: 248 PAVVHLQG 255
P ++ L G
Sbjct: 1485 PGLIGLIG 1492
Score = 87.0 bits (214), Expect = 3e-17
Identities = 56/173 (32%), Positives = 69/173 (39%), Gaps = 37/173 (21%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G ++G G PG G + G P P +G P + EPGEA +G
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGP-PGGIGNPGAVGEKGEPGEAGEPGLPGEG 1299
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
G GP + + ++GP G GPPGP
Sbjct: 1300 ----------------------------------GPPGPKGERGEKGESGPSGAAGPPGP 1325
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GPPG GP G PG G PG GPPG PGP G GPPG +G G + G+
Sbjct: 1326 KGPPGDDGPKGSPGPVGFPGDP--GPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376
Score = 83.6 bits (205), Expect = 3e-16
Identities = 67/211 (31%), Positives = 86/211 (40%), Gaps = 30/211 (14%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
L+ G G +G+PG G + G + P P G P P + PGE
Sbjct: 1073 LKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRP--GPQGPPGPAGEKGAPGEKGPQGP 1130
Query: 127 S-QDGHQ--MALLNFFFPDEKPYSEEESRRVRR--NKRSKSNEGADGPVKNKKKGKKAGP 181
+ +DG Q + L P P + + + K SK ++G GP G
Sbjct: 1131 AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ 1190
Query: 182 PGPNGPPGPPGP------------------PGPQGPPGIPGIPGIPG----TTVMGPPGP 219
PGP+G G PGP PGP GP G+ G+PG PG T +G GP
Sbjct: 1191 PGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGP 1250
Query: 220 PGPPGPQGPPGLQGPSGAADKAGTRENQPAV 250
PGPPGP+GP G G G G N AV
Sbjct: 1251 PGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281
Score = 82.4 bits (202), Expect = 6e-16
Identities = 64/206 (31%), Positives = 76/206 (36%), Gaps = 60/206 (29%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G R G G PG+ G G + P P G P P +P G A DG
Sbjct: 565 GLTGRPGPVGPPGSGGLKGEPGDVGPQGP-RGVQGPPGPAGKPGRRGRAG-----SDG-- 616
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+R + K + G DG + G PGP+GPPGPPG
Sbjct: 617 ------------------ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658
Query: 193 ------------------------------PPGPQGPPGIPGIPGIPGTT-VMGPPGPPG 221
PPGP GPPG+ G+ G PG +GP G PG
Sbjct: 659 DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPG 718
Query: 222 PPGPQGPPGLQ---GPSGAADKAGTR 244
PPG QG PG Q GP GA G +
Sbjct: 719 PPGQQGNPGAQGLPGPQGAIGPPGEK 744
Score = 82.4 bits (202), Expect = 6e-16
Identities = 78/272 (28%), Positives = 93/272 (34%), Gaps = 68/272 (25%)
Query: 13 PAAAPRERGSQGC-GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRE 71
P P E+G G G G P R G S +GF G
Sbjct: 857 PLGPPGEKGKLGVPGLPGYPGRQGPKGS----IGFPGFP--------------------- 891
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDP--DSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
GA GG GTPG G G P + G+P PK G A +
Sbjct: 892 -GANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGP 950
Query: 130 GHQMALLNFFFPDEKP-------YSEEESRRVRRNKRSKSNE-GADGPVKNKKKGKKAGP 181
F P P +R + K+ G G V + + GP
Sbjct: 951 NGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGP 1010
Query: 182 PGPNGPPGPPGPPGPQGPPGI---------------------PGIPGIPGTT-------- 212
G G PGPPGPPG QG PG+ PG+ G PG
Sbjct: 1011 MGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070
Query: 213 --VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
+ G GPPGPPGP G PG +GP+GAA G
Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102
Score = 82.4 bits (202), Expect = 6e-16
Identities = 59/174 (33%), Positives = 67/174 (38%), Gaps = 19/174 (10%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R E G + + G G PG G G P H G P P + PG A
Sbjct: 981 RGETGFQGKTGPPGPPGVVGPQGPTGETGPMGE-RGHPGPPGPPGEQGLPGLAGKEGTKG 1039
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
D L P + + G GPV GPPGP GP
Sbjct: 1040 DPGPAGLPGKDGPPGL-------------RGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG GP G G GIPG P GP GPPGP G +G PG +GP G A + G
Sbjct: 1087 GSPGERGPAGAAGPIGIPGRP-----GPQGPPGPAGEKGAPGEKGPQGPAGRDG 1135
Score = 79.7 bits (195), Expect = 4e-15
Identities = 58/175 (33%), Positives = 67/175 (38%), Gaps = 42/175 (24%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG + +G G PG G LG P P P P PG + D Q G
Sbjct: 662 ERGDDGEVGPRGLPGEPGPRGLLGPKGPPGP-------PGP------PGVTGM--DGQPG 706
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
K + +G GP + G PGP G GP
Sbjct: 707 --------------------------PKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740
Query: 191 PGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
PG GP G PG+PG+PG G G GPPG G QGPPG QGP G G +
Sbjct: 741 PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVK 795
Score = 79.7 bits (195), Expect = 4e-15
Identities = 63/181 (34%), Positives = 74/181 (40%), Gaps = 37/181 (20%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHL-------------GQPSPKQQPLE 117
E+GA+ G G PG +G + G P P L G P P P
Sbjct: 1406 EKGAKGEAGLEGPPGKTGPIGPQGA--PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGP 1463
Query: 118 ---PGEAALHSDS----QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV 170
PG L DS + GH L+ P P + E K + G GP
Sbjct: 1464 MGPPGLPGLKGDSGPKGEKGHP-GLIGLIGP---PGEQGE----------KGDRGLPGPQ 1509
Query: 171 KNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPP 229
+ + G GP+GP GPPGPPG GPPG G G G T G G PGPPGP GPP
Sbjct: 1510 GSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569
Query: 230 G 230
G
Sbjct: 1570 G 1570
Score = 78.6 bits (192), Expect = 9e-15
Identities = 62/188 (32%), Positives = 72/188 (38%), Gaps = 29/188 (15%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG---EAALHSDS 127
E G + +G G G+ G G P P +GQP P EPG + L
Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGP-QGPIGQPGPSGADGEPGPRGQQGLFGQK 1212
Query: 128 QDGHQMALLNFFFPDEK-PYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
D FP P + K + G GP GPPGP G
Sbjct: 1213 GDEGPRG-----FPGPPGPVGLQGLPGPPGEKGETGDVGQMGP---------PGPPGPRG 1258
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT----------VMGPPGPPGPPGPQGPPGLQGPSG 236
P G PG GPQGPPG G PG G + G GPPGP G +G G GPSG
Sbjct: 1259 PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSG 1318
Query: 237 AADKAGTR 244
AA G +
Sbjct: 1319 AAGPPGPK 1326
Score = 76.3 bits (186), Expect = 5e-14
Identities = 59/190 (31%), Positives = 71/190 (37%), Gaps = 36/190 (18%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G G PG G GG P P +G P P+ G L + +
Sbjct: 760 GPPGHPGKEGPPGEKGGQGPPGP-QGPIGYPGPRGVKGADGIRGLKGTKGEKGEDG---- 814
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQG 198
FP K + + R G DGP K +G GPNG PGP GPPG +G
Sbjct: 815 -FPGFK--GDMGIKGDRGEIGPPGPRGEDGPEGPKGRG------GPNGDPGPLGPPGEKG 865
Query: 199 PPGIPGIPGIPGTT----------------------VMGPPGPPGPPGPQGPPGLQGPSG 236
G+PG+PG PG G PGP G GP GP G +GP G
Sbjct: 866 KLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925
Query: 237 AADKAGTREN 246
K G + N
Sbjct: 926 ITGKPGPKGN 935
Score = 73.6 bits (179), Expect = 3e-13
Identities = 61/201 (30%), Positives = 73/201 (36%), Gaps = 28/201 (13%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R RG + G G G G G P+ P G P PK P PG+ L
Sbjct: 921 RGPRGITGKPGPKGNSGGDGPAGPPGERGPNGP-QGPTGFPGPKGPPGPPGKDGLPGHPG 979
Query: 129 DGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ P P + + + G GP + AG G G
Sbjct: 980 QRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG 1039
Query: 187 PPGPPGPPGPQGPPGIPGIPG---IPGTT----VMGPPGPPGPPGPQ------------G 227
PGP G PG GPPG+ G PG +PG + G GPPGPPGP G
Sbjct: 1040 DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAG 1099
Query: 228 P------PGLQGPSGAADKAG 242
P PG QGP G A + G
Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKG 1120
Score = 71.2 bits (173), Expect = 1e-12
Identities = 59/177 (33%), Positives = 65/177 (36%), Gaps = 25/177 (14%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG G G PG +G G GL H G P P P PG+ D +
Sbjct: 609 RGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGE 668
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
L P E R K G GP + GP G GP G
Sbjct: 669 VGPRGL-----PGEPG--------PRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQG 715
Query: 190 PPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPP------GPQGPPGLQGPSG 236
PGPPG QG PG G+PG G GP G PG P GP G PG +GP G
Sbjct: 716 EPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPG 772
Score = 66.2 bits (160), Expect = 5e-11
Identities = 50/173 (28%), Positives = 67/173 (38%), Gaps = 37/173 (21%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G +G PG GT+ G +G P + P PG M +L F
Sbjct: 475 GPAGLPGPPGTMGPTG----------QVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPF 524
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK--------KAGPPGPNGPPGP 190
F + G+ GP+ + ++ + + GP GP G
Sbjct: 525 RFG------------------GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGL 566
Query: 191 PGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PGP GPPG G+ G PG GP G GPPGP G PG +G +G+ G
Sbjct: 567 TGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARG 619
Score = 65.9 bits (159), Expect = 6e-11
Identities = 53/167 (31%), Positives = 58/167 (34%), Gaps = 86/167 (51%)
Query: 164 EGADGPVKNK-KKGKKA---------GPPGPNGPPGPPGPPGPQGP-------------- 199
EG GP K +KG+ A GPPGP GP G PGPPG GP
Sbjct: 443 EGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPG 502
Query: 200 ----PGIPGIPGIPGTTVM----------------------------------------- 214
PG G+PG PGT +M
Sbjct: 503 RPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAG 562
Query: 215 -----GPPGPPGPP------------GPQGPPGLQGPSGAADKAGTR 244
G PGP GPP GPQGP G+QGP G A K G R
Sbjct: 563 PMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRR 609
Score = 30.4 bits (67), Expect = 2.9
Identities = 18/54 (33%), Positives = 22/54 (40%), Gaps = 13/54 (24%)
Query: 203 PGIPGIPGTTVMGPPGPPGPPGP-------------QGPPGLQGPSGAADKAGT 243
PG+P T G GP G G +GPPG +GP+G GT
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGT 485
>gi|33598924 scavenger receptor class A, member 3 isoform 1 [Homo
sapiens]
Length = 606
Score = 92.0 bits (227), Expect = 8e-19
Identities = 65/167 (38%), Positives = 70/167 (41%), Gaps = 26/167 (15%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDP--DSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RGA G G G G +GG P D LG P+ QP E G
Sbjct: 456 RGAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPV-------- 507
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
G + + FP K SK + G GP GPPGP GPPG
Sbjct: 508 GERGPVGPRGFPGLKG--------------SKGSFGTGGPRGQPGPKGDIGPPGPEGPPG 553
Query: 190 PPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PGP GPQG PGI G G PG G GP G PG QGPPGL GP G
Sbjct: 554 SPGPSGPQGKPGIAGKTGSPGQ--RGAMGPKGEPGIQGPPGLPGPPG 598
Score = 73.6 bits (179), Expect = 3e-13
Identities = 42/98 (42%), Positives = 48/98 (48%), Gaps = 16/98 (16%)
Query: 161 KSNEGADGPVKNK-KKGKKA-----GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM 214
K + G GPV + KG GP GP G PG GP G +GP G G PG+ G+
Sbjct: 468 KGDMGVKGPVGGRGPKGDPGSLGPLGPQGPQGQPGEAGPVGERGPVGPRGFPGLKGSKGS 527
Query: 215 ----------GPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GP G GPPGP+GPPG GPSG K G
Sbjct: 528 FGTGGPRGQPGPKGDIGPPGPEGPPGSPGPSGPQGKPG 565
Score = 35.4 bits (80), Expect = 0.089
Identities = 15/32 (46%), Positives = 19/32 (59%)
Query: 211 TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
T + G PGPPGP G +G G++GP G G
Sbjct: 453 TILRGAPGPPGPRGFKGDMGVKGPVGGRGPKG 484
Score = 29.6 bits (65), Expect = 4.9
Identities = 15/40 (37%), Positives = 20/40 (50%)
Query: 218 GPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQG 257
G PGPPGP+G G G G G + + ++ L QG
Sbjct: 457 GAPGPPGPRGFKGDMGVKGPVGGRGPKGDPGSLGPLGPQG 496
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 91.7 bits (226), Expect = 1e-18
Identities = 64/177 (36%), Positives = 72/177 (40%), Gaps = 28/177 (15%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RGA +G G G +G G P P P+ P E GE
Sbjct: 675 RGAPGAVGAPGPAGATGDRGEAGAAGPAGPA-------GPRGSPGERGEVG--------- 718
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
A N F + ++ R K K G GP AGP GPNGPPGP
Sbjct: 719 -PAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGA---AGPAGPNGPPGPA 774
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPP------GPPGPPGPQGPPGLQGPSGAADKAG 242
G G GPPG+ G PG G T GPP GPPGPPGP G GL+GP G G
Sbjct: 775 GSRGDGGPPGMTGFPGAAGRT--GPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVG 829
Score = 78.2 bits (191), Expect = 1e-14
Identities = 59/181 (32%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSDSQ 128
ERGA+ G +G G +G + + G P+ P G P PG A
Sbjct: 740 ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPG 799
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
P +E R R ++ G G V + GP G G
Sbjct: 800 PSGISGPPG----PPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTA 855
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
GPPG PGPQG G PGI G+PG+ V G G PGP G GPPG +GP GA
Sbjct: 856 GPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSP 915
Query: 242 G 242
G
Sbjct: 916 G 916
Score = 75.9 bits (185), Expect = 6e-14
Identities = 41/94 (43%), Positives = 49/94 (52%), Gaps = 21/94 (22%)
Query: 168 GPVKNKKKGKKAGPPGP------NGPPGPPGPPGPQGPPGIPGI-------------PGI 208
GP ++ + GPPGP +GP GPPGPPGP GPPG+ G PG
Sbjct: 33 GPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGP 92
Query: 209 PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G +MGP GPPG G GP G QGP+G + G
Sbjct: 93 MG--LMGPRGPPGAAGAPGPQGFQGPAGEPGEPG 124
Score = 75.5 bits (184), Expect = 8e-14
Identities = 38/86 (44%), Positives = 46/86 (53%), Gaps = 2/86 (2%)
Query: 157 NKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGP 216
NK + G GP + K GP G G GPPGPPG +G PG G+PG G G
Sbjct: 359 NKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRA--GV 416
Query: 217 PGPPGPPGPQGPPGLQGPSGAADKAG 242
GPPG G GP G++GP+G A + G
Sbjct: 417 MGPPGSRGASGPAGVRGPNGDAGRPG 442
Score = 72.8 bits (177), Expect = 5e-13
Identities = 64/210 (30%), Positives = 80/210 (38%), Gaps = 15/210 (7%)
Query: 50 SLALHLLTLCCYLELRSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQP 109
+L L +TLC L L+ E + G G G G G D P G P
Sbjct: 9 TLLLLAVTLC--LATCQSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPT----GPP 62
Query: 110 SPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGP 169
P P PG + DG + L P R + +G GP
Sbjct: 63 GPPGPPGPPGLGGNFAAQYDGKGVGL------GPGPMGLMGPRGPPGAAGAPGPQGFQGP 116
Query: 170 VKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPP 229
+ + GP G GP GPPG G G PG PG PG G V+GP G G PG G P
Sbjct: 117 AGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERG--VVGPQGARGFPGTPGLP 174
Query: 230 GLQGPSGAADKAGTRENQPAVVHLQGQGSA 259
G +G G G + QP ++G+ A
Sbjct: 175 GFKGIRGHNGLDGLK-GQPGAPGVKGEPGA 203
Score = 72.4 bits (176), Expect = 7e-13
Identities = 57/172 (33%), Positives = 64/172 (37%), Gaps = 25/172 (14%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG G G PGT G L G+ + + GQP EPG
Sbjct: 155 ERGVVGPQGARGFPGTPG-LPGFKGIRGHNGLDGLKGQPGAPGVKGEPGA---------- 203
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
P E + R +R + GA GP + GP GP GP G
Sbjct: 204 ----------PGENGTPGQTGARGLPGERGRV--GAPGPAGARGSDGSVGPVGPAGPIGS 251
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GPPG G PG G G G GP GP GP G G PGL GP G G
Sbjct: 252 AGPPGFPGAPGPKGEIGAVGNA--GPAGPAGPRGEVGLPGLSGPVGPPGNPG 301
Score = 71.6 bits (174), Expect = 1e-12
Identities = 56/175 (32%), Positives = 63/175 (36%), Gaps = 37/175 (21%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLE---PGEAALHSDSQD 129
G + G G PG G G P P G P P E PGE LH +
Sbjct: 523 GPDGNNGAQGPPGPQGVQGGKGEQGPPGP-PGFQGLPGPSGPAGEVGKPGERGLHGE--- 578
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
F P R +R E AGP GP G G
Sbjct: 579 --------FGLPGPAG---------PRGERGPPGESG-----------AAGPTGPIGSRG 610
Query: 190 PPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
P GPPGP G G PG+ G GT GP GP G PG +G G+ G G + G R
Sbjct: 611 PSGPPGPDGNKGEPGVVGAVGTA--GPSGPSGLPGERGAAGIPGGKGEKGEPGLR 663
Score = 70.5 bits (171), Expect = 2e-12
Identities = 53/162 (32%), Positives = 64/162 (39%), Gaps = 27/162 (16%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + G G G SG + G + P P + G K +P E G L GH
Sbjct: 970 GPAGKHGNRGETGPSGPVGPAGAVGPRGP-SGPQGIRGDKGEPGEKGPRGL--PGLKGHN 1026
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ + + + G+ GP AGP GP GP GP G
Sbjct: 1027 --------------GLQGLPGIAGHHGDQGAPGSVGP---------AGPRGPAGPSGPAG 1063
Query: 193 PPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQG 233
G G PG G GI G GP GPPGPPGP GPPG+ G
Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105
Score = 69.7 bits (169), Expect = 4e-12
Identities = 58/185 (31%), Positives = 70/185 (37%), Gaps = 19/185 (10%)
Query: 71 ERGAESRLG---GSGTPGTSGTLSSLGGLDPDSPITSH--LGQPSPKQQPLEPGEA-ALH 124
ERG G +G G G G P PI S G P P EPG A+
Sbjct: 572 ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631
Query: 125 SDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP 184
+ G P P E + + K K G G + N + G PG
Sbjct: 632 TAGPSG----------PSGLP-GERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGA 680
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G PGP G G +G G G G G G PG G GP GP G GP+GAA + G +
Sbjct: 681 VGAPGPAGATGDRGEAGAAGPAGPAGP--RGSPGERGEVGPAGPNGFAGPAGAAGQPGAK 738
Query: 245 ENQPA 249
+ A
Sbjct: 739 GERGA 743
Score = 69.3 bits (168), Expect = 6e-12
Identities = 56/179 (31%), Positives = 71/179 (39%), Gaps = 23/179 (12%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG +G +G G G + G G +S G P+ P GE + +
Sbjct: 327 RGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGE 386
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG------PVKNKKKGKKAGPPG 183
P P +R + S+ GADG P ++ AG G
Sbjct: 387 AGSAG------PPGPP-------GLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRG 433
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
PNG G PG PG GP G+PG PG G G GP G PG G PG GP+GA + G
Sbjct: 434 PNGDAGRPGEPGLMGPRGLPGSPGNIGPA--GKEGPVGLPGIDGRPGPIGPAGARGEPG 490
Score = 66.6 bits (161), Expect = 4e-11
Identities = 67/211 (31%), Positives = 80/211 (37%), Gaps = 43/211 (20%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH--LGQPSPKQQPLEPG-EAALHS 125
R ERG G G PG G G P + S G P + PG +
Sbjct: 879 RGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGR 938
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV----KNKKKGKK--A 179
D Q GH+ E+ Y + G GPV K+ +G+ +
Sbjct: 939 DGQPGHK---------GERGYPGNIGP-----VGAAGAPGPHGPVGPAGKHGNRGETGPS 984
Query: 180 GPPGPNGPPGPPGPPGPQG------------PPGIP------GIPGIPGTT-VMGPPGPP 220
GP GP G GP GP GPQG P G+P G+ G+PG G G P
Sbjct: 985 GPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAP 1044
Query: 221 GPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
G GP GP G GPSG A K G R P V
Sbjct: 1045 GSVGPAGPRGPAGPSGPAGKDG-RTGHPGTV 1074
Score = 66.2 bits (160), Expect = 5e-11
Identities = 58/190 (30%), Positives = 70/190 (36%), Gaps = 43/190 (22%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
GA+ R G G PG+ G G G + D+ G P+ P PG + ++G
Sbjct: 409 GADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGN--IGPAGKEG 466
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
P P + G GP + + G PGP GP G
Sbjct: 467 ----------PVGLPGID-------------GRPGPIGPAGARGEPGNIGFPGPKGPTGD 503
Query: 191 PGP---------------PGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGP 234
PG PGP G G G PG G G GPPGPPG QG PG GP
Sbjct: 504 PGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGP 563
Query: 235 SGAADKAGTR 244
+G K G R
Sbjct: 564 AGEVGKPGER 573
Score = 64.3 bits (155), Expect = 2e-10
Identities = 60/210 (28%), Positives = 72/210 (34%), Gaps = 78/210 (37%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G R+G G G G+ S+G + P PI S G P P GE
Sbjct: 220 GERGRVGAPGPAGARGSDGSVGPVGPAGPIGS-AGPPGFPGAPGPKGEIG---------- 268
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ N G GP + + G GP GPPG PG
Sbjct: 269 ---------------------------AVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG 301
Query: 193 P------------PGPQGPPGIPGIPGIPGTT----------VMGPPGP----------- 219
PG G PG+PG GIPG ++G PGP
Sbjct: 302 ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361
Query: 220 -PGPPGPQGPP------GLQGPSGAADKAG 242
PG GPQGPP G +GP+G A AG
Sbjct: 362 EPGSAGPQGPPGPSGEEGKRGPNGEAGSAG 391
Score = 64.3 bits (155), Expect = 2e-10
Identities = 56/176 (31%), Positives = 66/176 (37%), Gaps = 16/176 (9%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPIT-----SHLGQPSPKQQPLEPGEAALHSDS 127
G G G PG G + + G P P+ + G+ P P+ P A+
Sbjct: 940 GQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSG-PVGPA-GAVGPRG 997
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
G Q + P EK R K + G G G PG GP
Sbjct: 998 PSGPQGIRGDKGEPGEKG--------PRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGP 1049
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GP GP GP GP G G G PGT G GP G GP GPPG GP G +G
Sbjct: 1050 AGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105
Score = 59.7 bits (143), Expect = 4e-09
Identities = 53/182 (29%), Positives = 68/182 (37%), Gaps = 20/182 (10%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
+RG G +G PG G S G GL +G P + G + D+
Sbjct: 380 KRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAG 439
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
+ L+ R + + + G +GPV + GP GP G
Sbjct: 440 RPGEPGLMG-------------PRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGAR 486
Query: 189 GPPGP---PGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRE 245
G PG PGP+GP G PG G G G G G PGP G G QGP G G +
Sbjct: 487 GEPGNIGFPGPKGPTGDPGKNGDKGHA--GLAGARGAPGPDGNNGAQGPPGPQGVQGGKG 544
Query: 246 NQ 247
Q
Sbjct: 545 EQ 546
Score = 59.7 bits (143), Expect = 4e-09
Identities = 56/181 (30%), Positives = 69/181 (38%), Gaps = 14/181 (7%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----Q 128
G G G PG +G + G P P + G P P + G D +
Sbjct: 772 GPAGSRGDGGPPGMTGFPGAAGRTGPPGP-SGISGPPGPPGPAGKEGLRGPRGDQGPVGR 830
Query: 129 DGHQMALLNFFFPDEK-PYSEEESRRVRRNKRSKSNEGADG----PVKNKKKGKK--AGP 181
G A+ F EK P E + + GA G P ++G AG
Sbjct: 831 TGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGA 890
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
G GP G GPPG +GPPG G PG+ G G G G PG GPPG G G +
Sbjct: 891 VGEPGPLGIAGPPGARGPPGAVGSPGVNGAP--GEAGRDGNPGNDGPPGRDGQPGHKGER 948
Query: 242 G 242
G
Sbjct: 949 G 949
Score = 58.9 bits (141), Expect = 8e-09
Identities = 40/109 (36%), Positives = 45/109 (41%), Gaps = 22/109 (20%)
Query: 163 NEGADGPVKNKKKGKKAGPPG------PNGPPGPPG---PPGPQGPPGIPGIPGIPGTT- 212
+ GA GP + AG PG P G PG PG P G +GP G+PGI G PG
Sbjct: 422 SRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481
Query: 213 ------------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPA 249
GP GP G PG G G G +GA G N A
Sbjct: 482 PAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGA 530
Score = 57.8 bits (138), Expect = 2e-08
Identities = 57/182 (31%), Positives = 71/182 (39%), Gaps = 26/182 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + G +G PG G G P P G+ +P PGE + G Q
Sbjct: 109 GPQGFQGPAGEPGEPGQTGPAGARGPAGP-PGKAGEDGHPGKPGRPGERGVV-----GPQ 162
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG----PVKNKKKGKKAGPPGPNGPP 188
A FP + + K + + G DG P KG+ G PG NG P
Sbjct: 163 GAR---GFPG--------TPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEP-GAPGENGTP 210
Query: 189 GPPGP---PGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G G PG +G G PG G G+ +GP GP GP G GPPG G G + G
Sbjct: 211 GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAV 270
Query: 245 EN 246
N
Sbjct: 271 GN 272
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 89.4 bits (220), Expect = 5e-18
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 32/186 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG R G G PGT G + L G + ++ G P P PG +
Sbjct: 559 RGQPGRKGLDGIPGTPG-VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP-- 615
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P P E + + + G GP + PGP GPPGPP
Sbjct: 616 ---------PGYGPQGEPGLQGTQGVPGAPGPPGEAGP--RGELSVSTPVPGPPGPPGPP 664
Query: 192 GPPGPQGPPGIPGI---------------PGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G PGPQGPPGIPG PGIPG +G PGPPGP G QG PG +G G
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG---IGFPGPPGPKGDQGFPGTKGSLG 721
Query: 237 AADKAG 242
K G
Sbjct: 722 CPGKMG 727
Score = 85.9 bits (211), Expect = 6e-17
Identities = 58/169 (34%), Positives = 72/169 (42%), Gaps = 11/169 (6%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+GA+ G G PG G ++G P P T G P P PG Q G+
Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-TGIEGFPGP------PGLPGAIIPGQTGN 1240
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ + P V K K + G GP GPPG G PG P
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300
Query: 192 GPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSG 236
G PGP+G PG G PG+ G +G GPPGP GP+GPPG++G G
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349
Score = 78.6 bits (192), Expect = 9e-15
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 18/180 (10%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHL-GQPSPKQQPLEPGEAAL 123
R++L+ E+G + +G G PG SG G + +P L G+P P PG +
Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
N FP E+ ++ K G GP + ++ G G
Sbjct: 314 KG-----------NRGFPG---LMGEDG--IKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GPPGP G GPQGP G PG+PG PG++ G G PG PG +G G +G G D GT
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGT 416
Score = 78.2 bits (191), Expect = 1e-14
Identities = 64/182 (35%), Positives = 72/182 (39%), Gaps = 33/182 (18%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSH----------LGQPSPKQQPLEPGEAALHSDSQ 128
G +G G G+ S G P P SH +G P PK P G+
Sbjct: 1236 GQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMG-----P 1290
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G A P P + + K K N G G + GPPGP GP
Sbjct: 1291 PGRLGAPGTPGLPG--PRGDPGFQGFPGVKGEKGNPGFLGSI---------GPPGPIGPK 1339
Query: 189 GPPGPPGPQGP------PGIPGIPGIPGTTVM-GPPGPPGPPGPQGPPGLQGPSGAADKA 241
GPPG G G PG PG PG PG M G PGPPGPPG GP G +G G K
Sbjct: 1340 GPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKP 1399
Query: 242 GT 243
GT
Sbjct: 1400 GT 1401
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/203 (31%), Positives = 75/203 (36%), Gaps = 45/203 (22%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG G G PG G S+G G+ LG P +P PG L D
Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK-- 1053
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
E YSE + G GP + G G G PG
Sbjct: 1054 ------------GEPGYSEG------------TRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Query: 190 PPG---PPGPQGPPGIPGIPGIPGTT-------------VMGPPGPPGPPGPQGPPGLQG 233
PPG P GP+G PG PG PG+PG ++GPPG GPPG G PG G
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149
Query: 234 PSGAADKAGTRENQPAVVHLQGQ 256
P G G R+ P +G+
Sbjct: 1150 PMGIRGDQG-RDGIPGPAGEKGE 1171
Score = 73.2 bits (178), Expect = 4e-13
Identities = 56/168 (33%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS-QD 129
GA G G PG G LG G+ G P P PG + D +D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160
Query: 130 GHQMALLNFFFPDEKPYSEE-ESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G P P E+ E+ +R + N GA G ++ G PG G
Sbjct: 1161 G---------IPG--PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G GP GP G G PG PG+PG + G G GPPG +G PG GP G
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 70/180 (38%), Gaps = 14/180 (7%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAAL------HSDSQDGHQ 132
G +G PG G + G + P HLG P+ P PG L H D
Sbjct: 1068 GPTGDPGLPGDMGKKGEMGQPGP-PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 133 MALLN---FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK-KKGKKAGPPGPNGPP 188
LL P P S + + +G GP K + G PPGP G P
Sbjct: 1127 KGLLGPPGIRGPPGLP-GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP 1185
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
G G G +G PG PG+PG G MG GP GP G +G PG G GA T P
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGA--MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP 1243
Score = 70.5 bits (171), Expect = 2e-12
Identities = 61/204 (29%), Positives = 74/204 (36%), Gaps = 37/204 (18%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + G G PG G G L +P+ G P P P G +
Sbjct: 623 EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
L PD +P K ++G G + K G PG G PG
Sbjct: 683 GDPGLPG---PDGEPGIPGIG--FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 191 PGPPG------PQGP--------------------PGIPGIPGIPGTTVM----GPPGPP 220
PG G P GP PG+PG+PG PG + G PG P
Sbjct: 738 PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQP 797
Query: 221 GPPGPQGPPG--LQGPSGAADKAG 242
GPPG QGPPG ++GP GA G
Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPG 821
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 24/189 (12%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG G G PG G + G D P GQP P + PG G
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQG 818
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK-----------KA 179
P ++ RR + K + G G ++ G+ +
Sbjct: 819 ---------LPGLNGLKGQQGRRGKTGP--KGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAA 238
GP G G PG PG GP G G+ G+ G PG GPPG PG PG +G PG+ G G
Sbjct: 868 GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927
Query: 239 DKAGTRENQ 247
G + Q
Sbjct: 928 GTPGAKGEQ 936
Score = 68.6 bits (166), Expect = 9e-12
Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 24/93 (25%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP----------------- 222
G PGP G PGPPG PGP GPPG PG G PG MGP GP G
Sbjct: 177 GAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG--AMGPRGPKGHMGERVIGHKGERGVKGL 234
Query: 223 PGPQGPPG-----LQGPSGAADKAGTRENQPAV 250
GP GPPG L GP D G + ++ A+
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/181 (30%), Positives = 66/181 (36%), Gaps = 38/181 (20%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G GTPG G + G P P PG S+ G + A
Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGP----------------PGVPGSPGSSRPGLRGA---- 393
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP-------NGPPGPP 191
P + R R K + G+ G + GPPGP GPPG
Sbjct: 394 --PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 192 GPPGPQGPPGIPGIPGIPGTT---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG G PGIPG+ G G + GPPG PG PG G G+ G GAA G
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 243 T 243
+
Sbjct: 512 S 512
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT----------V 213
+GA G K G PG G GP G PGPQGP G PG+PG+ G+
Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101
Query: 214 MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PG PG GP GL G G + G
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 26/199 (13%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSD 126
L+ ++G + G G PG G S + SP I H G+ P Q PG +
Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884
Query: 127 SQDGHQMALLNF---FFPDEKPYSE--------------EESRRVRRNKRSKSNEGADGP 169
+ + ++ F P P + + R K + ++G GP
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 170 VKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP------P 223
+ G PG G G PG G +G PG+PG+ G+ G + GP GPPGP
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG--LPGPAGPPGPRGDLGST 1002
Query: 224 GPQGPPGLQGPSGAADKAG 242
G G PGL+G G+ G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMG 1021
Score = 62.4 bits (150), Expect = 7e-10
Identities = 59/189 (31%), Positives = 71/189 (37%), Gaps = 42/189 (22%)
Query: 79 GGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
G G PGT G+L G + +P P G+P EP A G
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLP-----GKPGLPGAKGEPAVAMPGGPGTPG------- 756
Query: 138 FFFPDEKPYSEEESR----RVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP--P 191
FP E+ S E + + NEG DGP + + GPPG GPPG
Sbjct: 757 --FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGPPGRCIE 811
Query: 192 GPPGPQGPPGI------------------PGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
GP G QG PG+ PGIPG+ + G G PG PG QG G G
Sbjct: 812 GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871
Query: 234 PSGAADKAG 242
G G
Sbjct: 872 QRGYPGNPG 880
Score = 62.0 bits (149), Expect = 9e-10
Identities = 49/166 (29%), Positives = 70/166 (42%), Gaps = 18/166 (10%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
++ ++G+ G G PGT+G + G L P +P G P P+ P G + +
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP-----GLPGPRGDPGFQGFPGVKGE 1320
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSK---SNEGADGPVKNKKKGKKAGPPG 183
+ + + P + VR + + S G+ GP + G PG
Sbjct: 1321 KGNPGFLGSIG----PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPP 229
P GPPG GP GP+G PG G PG P GP G G G +G P
Sbjct: 1377 PPGPPGNLGPCGPRGKPGKDGKPGTP-----GPAGEKGNKGSKGEP 1417
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 8/81 (9%)
Query: 182 PGPNGPPGPPGP------PGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
PGP G PG PG PG QG G+ G PG PG T G PG PG PG QG PGL+G
Sbjct: 483 PGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT--GLPGFPGFPGAQGDPGLKGEK 540
Query: 236 GAADKAGTRENQPAVVHLQGQ 256
G + + P L+GQ
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQ 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 53/172 (30%), Positives = 60/172 (34%), Gaps = 15/172 (8%)
Query: 79 GGSGTPGTSGTLSSLGGLDPD--SPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G GTPG G G P S + G+P K PGE L
Sbjct: 925 GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
P P R + S N G G G PG G G G PG
Sbjct: 985 GLPGPAGPPGP-------RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 197 QGPPGIPGIPGI------PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG+PGI G+ PG + PGPPGP G G PG G G + G
Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 175 KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQG 233
KG+K P G G PG PG +G PG G+ GIPGT V G PGP G G G QG
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596
Query: 234 PSGAADKAGT 243
P G G+
Sbjct: 597 PPGDPGSPGS 606
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/230 (27%), Positives = 80/230 (34%), Gaps = 40/230 (17%)
Query: 66 SELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP---ITSHLGQPSPKQQPLEPGEAA 122
S+ R R + +G G+PG +G+ G P P I G P P G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461
Query: 123 LHS-DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ D G L P + K +GA G + G
Sbjct: 462 IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521
Query: 182 PGPNGPPGPPGPPG----------PQGPPGIPGIP------------GIPGTT-VMGPPG 218
PG G PG G PG P+G G+PG P GIPGT V G PG
Sbjct: 522 PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 219 P------------PGPPGPQGPPGLQGPSGAADKAG-TRENQPAVVHLQG 255
P GPPG G PG GP+G A G + +P + QG
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/81 (41%), Positives = 36/81 (44%), Gaps = 18/81 (22%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGI---PGIPGTTVM----GPP-----------GPPG 221
GP G G PG G G QG PG+PG PGIPG + G P G PG
Sbjct: 115 GPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPG 174
Query: 222 PPGPQGPPGLQGPSGAADKAG 242
PG GP GL GP G G
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVG 195
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G G +G G PG PG PG G GP G PGPQGP G G G G R
Sbjct: 43 GAKGEKGEKGFPGPPGSPGQK--GFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 89.4 bits (220), Expect = 5e-18
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 32/186 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG R G G PGT G + L G + ++ G P P PG +
Sbjct: 559 RGQPGRKGLDGIPGTPG-VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP-- 615
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P P E + + + G GP + PGP GPPGPP
Sbjct: 616 ---------PGYGPQGEPGLQGTQGVPGAPGPPGEAGP--RGELSVSTPVPGPPGPPGPP 664
Query: 192 GPPGPQGPPGIPGI---------------PGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G PGPQGPPGIPG PGIPG +G PGPPGP G QG PG +G G
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG---IGFPGPPGPKGDQGFPGTKGSLG 721
Query: 237 AADKAG 242
K G
Sbjct: 722 CPGKMG 727
Score = 85.9 bits (211), Expect = 6e-17
Identities = 58/169 (34%), Positives = 72/169 (42%), Gaps = 11/169 (6%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+GA+ G G PG G ++G P P T G P P PG Q G+
Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-TGIEGFPGP------PGLPGAIIPGQTGN 1240
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ + P V K K + G GP GPPG G PG P
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300
Query: 192 GPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSG 236
G PGP+G PG G PG+ G +G GPPGP GP+GPPG++G G
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349
Score = 78.6 bits (192), Expect = 9e-15
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 18/180 (10%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHL-GQPSPKQQPLEPGEAAL 123
R++L+ E+G + +G G PG SG G + +P L G+P P PG +
Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
N FP E+ ++ K G GP + ++ G G
Sbjct: 314 KG-----------NRGFPG---LMGEDG--IKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GPPGP G GPQGP G PG+PG PG++ G G PG PG +G G +G G D GT
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGT 416
Score = 75.5 bits (184), Expect = 8e-14
Identities = 60/201 (29%), Positives = 84/201 (41%), Gaps = 17/201 (8%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
++ ++G+ G G PGT+G + G L P +P G P P+ P G + +
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP-----GLPGPRGDPGFQGFPGVKGE 1320
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSK---SNEGADGPVKNKKKGKKAGPPG 183
+ + + P + VR + + S G+ GP + G PG
Sbjct: 1321 KGNPGFLGSIG----PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P GPPG GP GP+G PG G PG PG G G PGP G G PGL+G G +
Sbjct: 1377 PPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436
Query: 240 KAGTRENQPAVVHLQGQGSAI 260
T + V Q +AI
Sbjct: 1437 SPATWTTRGFVFTRHSQTTAI 1457
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/203 (31%), Positives = 75/203 (36%), Gaps = 45/203 (22%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG G G PG G S+G G+ LG P +P PG L D
Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK-- 1053
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
E YSE + G GP + G G G PG
Sbjct: 1054 ------------GEPGYSEG------------TRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Query: 190 PPG---PPGPQGPPGIPGIPGIPGTT-------------VMGPPGPPGPPGPQGPPGLQG 233
PPG P GP+G PG PG PG+PG ++GPPG GPPG G PG G
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149
Query: 234 PSGAADKAGTRENQPAVVHLQGQ 256
P G G R+ P +G+
Sbjct: 1150 PMGIRGDQG-RDGIPGPAGEKGE 1171
Score = 73.2 bits (178), Expect = 4e-13
Identities = 56/168 (33%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS-QD 129
GA G G PG G LG G+ G P P PG + D +D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160
Query: 130 GHQMALLNFFFPDEKPYSEE-ESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G P P E+ E+ +R + N GA G ++ G PG G
Sbjct: 1161 G---------IPG--PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G GP GP G G PG PG+PG + G G GPPG +G PG GP G
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 70/180 (38%), Gaps = 14/180 (7%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAAL------HSDSQDGHQ 132
G +G PG G + G + P HLG P+ P PG L H D
Sbjct: 1068 GPTGDPGLPGDMGKKGEMGQPGP-PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 133 MALLN---FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK-KKGKKAGPPGPNGPP 188
LL P P S + + +G GP K + G PPGP G P
Sbjct: 1127 KGLLGPPGIRGPPGLP-GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP 1185
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
G G G +G PG PG+PG G MG GP GP G +G PG G GA T P
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGA--MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP 1243
Score = 70.5 bits (171), Expect = 2e-12
Identities = 61/204 (29%), Positives = 74/204 (36%), Gaps = 37/204 (18%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + G G PG G G L +P+ G P P P G +
Sbjct: 623 EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
L PD +P K ++G G + K G PG G PG
Sbjct: 683 GDPGLPG---PDGEPGIPGIG--FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 191 PGPPG------PQGP--------------------PGIPGIPGIPGTTVM----GPPGPP 220
PG G P GP PG+PG+PG PG + G PG P
Sbjct: 738 PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQP 797
Query: 221 GPPGPQGPPG--LQGPSGAADKAG 242
GPPG QGPPG ++GP GA G
Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPG 821
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 24/189 (12%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG G G PG G + G D P GQP P + PG G
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQG 818
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK-----------KA 179
P ++ RR + K + G G ++ G+ +
Sbjct: 819 ---------LPGLNGLKGQQGRRGKTGP--KGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAA 238
GP G G PG PG GP G G+ G+ G PG GPPG PG PG +G PG+ G G
Sbjct: 868 GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927
Query: 239 DKAGTRENQ 247
G + Q
Sbjct: 928 GTPGAKGEQ 936
Score = 68.6 bits (166), Expect = 9e-12
Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 24/93 (25%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP----------------- 222
G PGP G PGPPG PGP GPPG PG G PG MGP GP G
Sbjct: 177 GAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG--AMGPRGPKGHMGERVIGHKGERGVKGL 234
Query: 223 PGPQGPPG-----LQGPSGAADKAGTRENQPAV 250
GP GPPG L GP D G + ++ A+
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/181 (30%), Positives = 66/181 (36%), Gaps = 38/181 (20%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G GTPG G + G P P PG S+ G + A
Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGP----------------PGVPGSPGSSRPGLRGA---- 393
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP-------NGPPGPP 191
P + R R K + G+ G + GPPGP GPPG
Sbjct: 394 --PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 192 GPPGPQGPPGIPGIPGIPGTT---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG G PGIPG+ G G + GPPG PG PG G G+ G GAA G
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 243 T 243
+
Sbjct: 512 S 512
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT----------V 213
+GA G K G PG G GP G PGPQGP G PG+PG+ G+
Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101
Query: 214 MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PG PG GP GL G G + G
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 26/199 (13%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSD 126
L+ ++G + G G PG G S + SP I H G+ P Q PG +
Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884
Query: 127 SQDGHQMALLNF---FFPDEKPYSE--------------EESRRVRRNKRSKSNEGADGP 169
+ + ++ F P P + + R K + ++G GP
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 170 VKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP------P 223
+ G PG G G PG G +G PG+PG+ G+ G + GP GPPGP
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG--LPGPAGPPGPRGDLGST 1002
Query: 224 GPQGPPGLQGPSGAADKAG 242
G G PGL+G G+ G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMG 1021
Score = 62.4 bits (150), Expect = 7e-10
Identities = 59/189 (31%), Positives = 71/189 (37%), Gaps = 42/189 (22%)
Query: 79 GGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
G G PGT G+L G + +P P G+P EP A G
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLP-----GKPGLPGAKGEPAVAMPGGPGTPG------- 756
Query: 138 FFFPDEKPYSEEESR----RVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP--P 191
FP E+ S E + + NEG DGP + + GPPG GPPG
Sbjct: 757 --FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGPPGRCIE 811
Query: 192 GPPGPQGPPGI------------------PGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
GP G QG PG+ PGIPG+ + G G PG PG QG G G
Sbjct: 812 GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871
Query: 234 PSGAADKAG 242
G G
Sbjct: 872 QRGYPGNPG 880
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 8/81 (9%)
Query: 182 PGPNGPPGPPGP------PGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
PGP G PG PG PG QG G+ G PG PG T G PG PG PG QG PGL+G
Sbjct: 483 PGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT--GLPGFPGFPGAQGDPGLKGEK 540
Query: 236 GAADKAGTRENQPAVVHLQGQ 256
G + + P L+GQ
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQ 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 53/172 (30%), Positives = 60/172 (34%), Gaps = 15/172 (8%)
Query: 79 GGSGTPGTSGTLSSLGGLDPD--SPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G GTPG G G P S + G+P K PGE L
Sbjct: 925 GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
P P R + S N G G G PG G G G PG
Sbjct: 985 GLPGPAGPPGP-------RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 197 QGPPGIPGIPGI------PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG+PGI G+ PG + PGPPGP G G PG G G + G
Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 175 KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQG 233
KG+K P G G PG PG +G PG G+ GIPGT V G PGP G G G QG
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596
Query: 234 PSGAADKAGT 243
P G G+
Sbjct: 597 PPGDPGSPGS 606
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/230 (27%), Positives = 80/230 (34%), Gaps = 40/230 (17%)
Query: 66 SELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP---ITSHLGQPSPKQQPLEPGEAA 122
S+ R R + +G G+PG +G+ G P P I G P P G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461
Query: 123 LHS-DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ D G L P + K +GA G + G
Sbjct: 462 IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521
Query: 182 PGPNGPPGPPGPPG----------PQGPPGIPGIP------------GIPGTT-VMGPPG 218
PG G PG G PG P+G G+PG P GIPGT V G PG
Sbjct: 522 PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 219 P------------PGPPGPQGPPGLQGPSGAADKAG-TRENQPAVVHLQG 255
P GPPG G PG GP+G A G + +P + QG
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/81 (41%), Positives = 36/81 (44%), Gaps = 18/81 (22%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGI---PGIPGTTVM----GPP-----------GPPG 221
GP G G PG G G QG PG+PG PGIPG + G P G PG
Sbjct: 115 GPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPG 174
Query: 222 PPGPQGPPGLQGPSGAADKAG 242
PG GP GL GP G G
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVG 195
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G G +G G PG PG PG G GP G PGPQGP G G G G R
Sbjct: 43 GAKGEKGEKGFPGPPGSPGQK--GFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 89.4 bits (220), Expect = 5e-18
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 32/186 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG R G G PGT G + L G + ++ G P P PG +
Sbjct: 559 RGQPGRKGLDGIPGTPG-VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP-- 615
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P P E + + + G GP + PGP GPPGPP
Sbjct: 616 ---------PGYGPQGEPGLQGTQGVPGAPGPPGEAGP--RGELSVSTPVPGPPGPPGPP 664
Query: 192 GPPGPQGPPGIPGI---------------PGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G PGPQGPPGIPG PGIPG +G PGPPGP G QG PG +G G
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG---IGFPGPPGPKGDQGFPGTKGSLG 721
Query: 237 AADKAG 242
K G
Sbjct: 722 CPGKMG 727
Score = 85.9 bits (211), Expect = 6e-17
Identities = 58/169 (34%), Positives = 72/169 (42%), Gaps = 11/169 (6%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+GA+ G G PG G ++G P P T G P P PG Q G+
Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-TGIEGFPGP------PGLPGAIIPGQTGN 1240
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ + P V K K + G GP GPPG G PG P
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300
Query: 192 GPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSG 236
G PGP+G PG G PG+ G +G GPPGP GP+GPPG++G G
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349
Score = 78.6 bits (192), Expect = 9e-15
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 18/180 (10%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHL-GQPSPKQQPLEPGEAAL 123
R++L+ E+G + +G G PG SG G + +P L G+P P PG +
Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
N FP E+ ++ K G GP + ++ G G
Sbjct: 314 KG-----------NRGFPG---LMGEDG--IKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GPPGP G GPQGP G PG+PG PG++ G G PG PG +G G +G G D GT
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGT 416
Score = 75.5 bits (184), Expect = 8e-14
Identities = 60/201 (29%), Positives = 84/201 (41%), Gaps = 17/201 (8%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
++ ++G+ G G PGT+G + G L P +P G P P+ P G + +
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP-----GLPGPRGDPGFQGFPGVKGE 1320
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSK---SNEGADGPVKNKKKGKKAGPPG 183
+ + + P + VR + + S G+ GP + G PG
Sbjct: 1321 KGNPGFLGSIG----PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P GPPG GP GP+G PG G PG PG G G PGP G G PGL+G G +
Sbjct: 1377 PPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436
Query: 240 KAGTRENQPAVVHLQGQGSAI 260
T + V Q +AI
Sbjct: 1437 SPATWTTRGFVFTRHSQTTAI 1457
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/203 (31%), Positives = 75/203 (36%), Gaps = 45/203 (22%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG G G PG G S+G G+ LG P +P PG L D
Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK-- 1053
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
E YSE + G GP + G G G PG
Sbjct: 1054 ------------GEPGYSEG------------TRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Query: 190 PPG---PPGPQGPPGIPGIPGIPGTT-------------VMGPPGPPGPPGPQGPPGLQG 233
PPG P GP+G PG PG PG+PG ++GPPG GPPG G PG G
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149
Query: 234 PSGAADKAGTRENQPAVVHLQGQ 256
P G G R+ P +G+
Sbjct: 1150 PMGIRGDQG-RDGIPGPAGEKGE 1171
Score = 73.2 bits (178), Expect = 4e-13
Identities = 56/168 (33%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS-QD 129
GA G G PG G LG G+ G P P PG + D +D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160
Query: 130 GHQMALLNFFFPDEKPYSEE-ESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G P P E+ E+ +R + N GA G ++ G PG G
Sbjct: 1161 G---------IPG--PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G GP GP G G PG PG+PG + G G GPPG +G PG GP G
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 70/180 (38%), Gaps = 14/180 (7%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAAL------HSDSQDGHQ 132
G +G PG G + G + P HLG P+ P PG L H D
Sbjct: 1068 GPTGDPGLPGDMGKKGEMGQPGP-PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 133 MALLN---FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK-KKGKKAGPPGPNGPP 188
LL P P S + + +G GP K + G PPGP G P
Sbjct: 1127 KGLLGPPGIRGPPGLP-GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP 1185
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
G G G +G PG PG+PG G MG GP GP G +G PG G GA T P
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGA--MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP 1243
Score = 70.5 bits (171), Expect = 2e-12
Identities = 61/204 (29%), Positives = 74/204 (36%), Gaps = 37/204 (18%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + G G PG G G L +P+ G P P P G +
Sbjct: 623 EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
L PD +P K ++G G + K G PG G PG
Sbjct: 683 GDPGLPG---PDGEPGIPGIG--FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 191 PGPPG------PQGP--------------------PGIPGIPGIPGTTVM----GPPGPP 220
PG G P GP PG+PG+PG PG + G PG P
Sbjct: 738 PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQP 797
Query: 221 GPPGPQGPPG--LQGPSGAADKAG 242
GPPG QGPPG ++GP GA G
Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPG 821
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 24/189 (12%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG G G PG G + G D P GQP P + PG G
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQG 818
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK-----------KA 179
P ++ RR + K + G G ++ G+ +
Sbjct: 819 ---------LPGLNGLKGQQGRRGKTGP--KGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAA 238
GP G G PG PG GP G G+ G+ G PG GPPG PG PG +G PG+ G G
Sbjct: 868 GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927
Query: 239 DKAGTRENQ 247
G + Q
Sbjct: 928 GTPGAKGEQ 936
Score = 68.6 bits (166), Expect = 9e-12
Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 24/93 (25%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP----------------- 222
G PGP G PGPPG PGP GPPG PG G PG MGP GP G
Sbjct: 177 GAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG--AMGPRGPKGHMGERVIGHKGERGVKGL 234
Query: 223 PGPQGPPG-----LQGPSGAADKAGTRENQPAV 250
GP GPPG L GP D G + ++ A+
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/181 (30%), Positives = 66/181 (36%), Gaps = 38/181 (20%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G GTPG G + G P P PG S+ G + A
Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGP----------------PGVPGSPGSSRPGLRGA---- 393
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP-------NGPPGPP 191
P + R R K + G+ G + GPPGP GPPG
Sbjct: 394 --PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 192 GPPGPQGPPGIPGIPGIPGTT---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG G PGIPG+ G G + GPPG PG PG G G+ G GAA G
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 243 T 243
+
Sbjct: 512 S 512
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT----------V 213
+GA G K G PG G GP G PGPQGP G PG+PG+ G+
Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101
Query: 214 MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PG PG GP GL G G + G
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 26/199 (13%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSD 126
L+ ++G + G G PG G S + SP I H G+ P Q PG +
Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884
Query: 127 SQDGHQMALLNF---FFPDEKPYSE--------------EESRRVRRNKRSKSNEGADGP 169
+ + ++ F P P + + R K + ++G GP
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 170 VKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP------P 223
+ G PG G G PG G +G PG+PG+ G+ G + GP GPPGP
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG--LPGPAGPPGPRGDLGST 1002
Query: 224 GPQGPPGLQGPSGAADKAG 242
G G PGL+G G+ G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMG 1021
Score = 62.4 bits (150), Expect = 7e-10
Identities = 59/189 (31%), Positives = 71/189 (37%), Gaps = 42/189 (22%)
Query: 79 GGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
G G PGT G+L G + +P P G+P EP A G
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLP-----GKPGLPGAKGEPAVAMPGGPGTPG------- 756
Query: 138 FFFPDEKPYSEEESR----RVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP--P 191
FP E+ S E + + NEG DGP + + GPPG GPPG
Sbjct: 757 --FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGPPGRCIE 811
Query: 192 GPPGPQGPPGI------------------PGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
GP G QG PG+ PGIPG+ + G G PG PG QG G G
Sbjct: 812 GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871
Query: 234 PSGAADKAG 242
G G
Sbjct: 872 QRGYPGNPG 880
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 8/81 (9%)
Query: 182 PGPNGPPGPPGP------PGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
PGP G PG PG PG QG G+ G PG PG T G PG PG PG QG PGL+G
Sbjct: 483 PGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT--GLPGFPGFPGAQGDPGLKGEK 540
Query: 236 GAADKAGTRENQPAVVHLQGQ 256
G + + P L+GQ
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQ 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 53/172 (30%), Positives = 60/172 (34%), Gaps = 15/172 (8%)
Query: 79 GGSGTPGTSGTLSSLGGLDPD--SPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G GTPG G G P S + G+P K PGE L
Sbjct: 925 GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
P P R + S N G G G PG G G G PG
Sbjct: 985 GLPGPAGPPGP-------RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 197 QGPPGIPGIPGI------PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG+PGI G+ PG + PGPPGP G G PG G G + G
Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 175 KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQG 233
KG+K P G G PG PG +G PG G+ GIPGT V G PGP G G G QG
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596
Query: 234 PSGAADKAGT 243
P G G+
Sbjct: 597 PPGDPGSPGS 606
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/230 (27%), Positives = 80/230 (34%), Gaps = 40/230 (17%)
Query: 66 SELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP---ITSHLGQPSPKQQPLEPGEAA 122
S+ R R + +G G+PG +G+ G P P I G P P G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461
Query: 123 LHS-DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ D G L P + K +GA G + G
Sbjct: 462 IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521
Query: 182 PGPNGPPGPPGPPG----------PQGPPGIPGIP------------GIPGTT-VMGPPG 218
PG G PG G PG P+G G+PG P GIPGT V G PG
Sbjct: 522 PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 219 P------------PGPPGPQGPPGLQGPSGAADKAG-TRENQPAVVHLQG 255
P GPPG G PG GP+G A G + +P + QG
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/81 (41%), Positives = 36/81 (44%), Gaps = 18/81 (22%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGI---PGIPGTTVM----GPP-----------GPPG 221
GP G G PG G G QG PG+PG PGIPG + G P G PG
Sbjct: 115 GPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPG 174
Query: 222 PPGPQGPPGLQGPSGAADKAG 242
PG GP GL GP G G
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVG 195
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G G +G G PG PG PG G GP G PGPQGP G G G G R
Sbjct: 43 GAKGEKGEKGFPGPPGSPGQK--GFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 89.4 bits (220), Expect = 5e-18
Identities = 64/186 (34%), Positives = 75/186 (40%), Gaps = 32/186 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG R G G PGT G + L G + ++ G P P PG +
Sbjct: 559 RGQPGRKGLDGIPGTPG-VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGP-- 615
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P P E + + + G GP + PGP GPPGPP
Sbjct: 616 ---------PGYGPQGEPGLQGTQGVPGAPGPPGEAGP--RGELSVSTPVPGPPGPPGPP 664
Query: 192 GPPGPQGPPGIPGI---------------PGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G PGPQGPPGIPG PGIPG +G PGPPGP G QG PG +G G
Sbjct: 665 GHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPG---IGFPGPPGPKGDQGFPGTKGSLG 721
Query: 237 AADKAG 242
K G
Sbjct: 722 CPGKMG 727
Score = 85.9 bits (211), Expect = 6e-17
Identities = 58/169 (34%), Positives = 72/169 (42%), Gaps = 11/169 (6%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+GA+ G G PG G ++G P P T G P P PG Q G+
Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-TGIEGFPGP------PGLPGAIIPGQTGN 1240
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ + P V K K + G GP GPPG G PG P
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300
Query: 192 GPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSG 236
G PGP+G PG G PG+ G +G GPPGP GP+GPPG++G G
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPG 1349
Score = 78.6 bits (192), Expect = 9e-15
Identities = 59/180 (32%), Positives = 80/180 (44%), Gaps = 18/180 (10%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHL-GQPSPKQQPLEPGEAAL 123
R++L+ E+G + +G G PG SG G + +P L G+P P PG +
Sbjct: 254 RTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGV 313
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
N FP E+ ++ K G GP + ++ G G
Sbjct: 314 KG-----------NRGFPG---LMGEDG--IKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GPPGP G GPQGP G PG+PG PG++ G G PG PG +G G +G G D GT
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG-KDAMGT 416
Score = 75.5 bits (184), Expect = 8e-14
Identities = 60/201 (29%), Positives = 84/201 (41%), Gaps = 17/201 (8%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLD-PDSPITSHLGQPSPKQQPLEPGEAALHSD 126
++ ++G+ G G PGT+G + G L P +P G P P+ P G + +
Sbjct: 1266 IKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP-----GLPGPRGDPGFQGFPGVKGE 1320
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSK---SNEGADGPVKNKKKGKKAGPPG 183
+ + + P + VR + + S G+ GP + G PG
Sbjct: 1321 KGNPGFLGSIG----PPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPG 1376
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P GPPG GP GP+G PG G PG PG G G PGP G G PGL+G G +
Sbjct: 1377 PPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSG 1436
Query: 240 KAGTRENQPAVVHLQGQGSAI 260
T + V Q +AI
Sbjct: 1437 SPATWTTRGFVFTRHSQTTAI 1457
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/203 (31%), Positives = 75/203 (36%), Gaps = 45/203 (22%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
RG G G PG G S+G G+ LG P +P PG L D
Sbjct: 996 RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDK-- 1053
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPG 189
E YSE + G GP + G G G PG
Sbjct: 1054 ------------GEPGYSEG------------TRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Query: 190 PPG---PPGPQGPPGIPGIPGIPGTT-------------VMGPPGPPGPPGPQGPPGLQG 233
PPG P GP+G PG PG PG+PG ++GPPG GPPG G PG G
Sbjct: 1090 PPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPG 1149
Query: 234 PSGAADKAGTRENQPAVVHLQGQ 256
P G G R+ P +G+
Sbjct: 1150 PMGIRGDQG-RDGIPGPAGEKGE 1171
Score = 73.2 bits (178), Expect = 4e-13
Identities = 56/168 (33%), Positives = 68/168 (40%), Gaps = 15/168 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS-QD 129
GA G G PG G LG G+ G P P PG + D +D
Sbjct: 1101 GAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRD 1160
Query: 130 GHQMALLNFFFPDEKPYSEE-ESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G P P E+ E+ +R + N GA G ++ G PG G
Sbjct: 1161 G---------IPG--PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM 1209
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
G GP GP G G PG PG+PG + G G GPPG +G PG GP G
Sbjct: 1210 GDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Score = 72.4 bits (176), Expect = 7e-13
Identities = 59/180 (32%), Positives = 70/180 (38%), Gaps = 14/180 (7%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAAL------HSDSQDGHQ 132
G +G PG G + G + P HLG P+ P PG L H D
Sbjct: 1068 GPTGDPGLPGDMGKKGEMGQPGP-PGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 133 MALLN---FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK-KKGKKAGPPGPNGPP 188
LL P P S + + +G GP K + G PPGP G P
Sbjct: 1127 KGLLGPPGIRGPPGLP-GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNP 1185
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
G G G +G PG PG+PG G MG GP GP G +G PG G GA T P
Sbjct: 1186 GAQGAKGDRGAPGFPGLPGRKGA--MGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGP 1243
Score = 70.5 bits (171), Expect = 2e-12
Identities = 61/204 (29%), Positives = 74/204 (36%), Gaps = 37/204 (18%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + G G PG G G L +P+ G P P P G +
Sbjct: 623 EPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKC 682
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
L PD +P K ++G G + K G PG G PG
Sbjct: 683 GDPGLPG---PDGEPGIPGIG--FPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGL 737
Query: 191 PGPPG------PQGP--------------------PGIPGIPGIPGTTVM----GPPGPP 220
PG G P GP PG+PG+PG PG + G PG P
Sbjct: 738 PGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQP 797
Query: 221 GPPGPQGPPG--LQGPSGAADKAG 242
GPPG QGPPG ++GP GA G
Sbjct: 798 GPPGEQGPPGRCIEGPRGAQGLPG 821
Score = 68.9 bits (167), Expect = 7e-12
Identities = 56/189 (29%), Positives = 71/189 (37%), Gaps = 24/189 (12%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG G G PG G + G D P GQP P + PG G
Sbjct: 760 ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP-RGDPGQPGPPGEQGPPGRCIEGPRGAQG 818
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK-----------KA 179
P ++ RR + K + G G ++ G+ +
Sbjct: 819 ---------LPGLNGLKGQQGRRGKTGP--KGDPGIPGLDRSGFPGETGSPGIPGHQGEM 867
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAA 238
GP G G PG PG GP G G+ G+ G PG GPPG PG PG +G PG+ G G
Sbjct: 868 GPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927
Query: 239 DKAGTRENQ 247
G + Q
Sbjct: 928 GTPGAKGEQ 936
Score = 68.6 bits (166), Expect = 9e-12
Identities = 40/93 (43%), Positives = 44/93 (47%), Gaps = 24/93 (25%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP----------------- 222
G PGP G PGPPG PGP GPPG PG G PG MGP GP G
Sbjct: 177 GAPGPQGLPGPPGFPGPVGPPGPPGFFGFPG--AMGPRGPKGHMGERVIGHKGERGVKGL 234
Query: 223 PGPQGPPG-----LQGPSGAADKAGTRENQPAV 250
GP GPPG L GP D G + ++ A+
Sbjct: 235 TGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAM 267
Score = 68.2 bits (165), Expect = 1e-11
Identities = 55/181 (30%), Positives = 66/181 (36%), Gaps = 38/181 (20%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G GTPG G + G P P PG S+ G + A
Sbjct: 354 GDEGTPGPPGPRGARGPQGPSGP----------------PGVPGSPGSSRPGLRGA---- 393
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP-------NGPPGPP 191
P + R R K + G+ G + GPPGP GPPG
Sbjct: 394 --PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDH 451
Query: 192 GPPGPQGPPGIPGIPGIPGTT---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG G PGIPG+ G G + GPPG PG PG G G+ G GAA G
Sbjct: 452 GLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKG 511
Query: 243 T 243
+
Sbjct: 512 S 512
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/89 (41%), Positives = 42/89 (47%), Gaps = 10/89 (11%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT----------V 213
+GA G K G PG G GP G PGPQGP G PG+PG+ G+
Sbjct: 42 DGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGF 101
Query: 214 MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PG PG GP GL G G + G
Sbjct: 102 SGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/199 (27%), Positives = 79/199 (39%), Gaps = 26/199 (13%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSD 126
L+ ++G + G G PG G S + SP I H G+ P Q PG +
Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884
Query: 127 SQDGHQMALLNF---FFPDEKPYSE--------------EESRRVRRNKRSKSNEGADGP 169
+ + ++ F P P + + R K + ++G GP
Sbjct: 885 PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP 944
Query: 170 VKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP------P 223
+ G PG G G PG G +G PG+PG+ G+ G + GP GPPGP
Sbjct: 945 SEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG--LPGPAGPPGPRGDLGST 1002
Query: 224 GPQGPPGLQGPSGAADKAG 242
G G PGL+G G+ G
Sbjct: 1003 GNPGEPGLRGIPGSMGNMG 1021
Score = 62.4 bits (150), Expect = 7e-10
Identities = 59/189 (31%), Positives = 71/189 (37%), Gaps = 42/189 (22%)
Query: 79 GGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
G G PGT G+L G + +P P G+P EP A G
Sbjct: 709 GDQGFPGTKGSLGCPGKMGEPGLP-----GKPGLPGAKGEPAVAMPGGPGTPG------- 756
Query: 138 FFFPDEKPYSEEESR----RVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP--P 191
FP E+ S E + + NEG DGP + + GPPG GPPG
Sbjct: 757 --FPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGP---RGDPGQPGPPGEQGPPGRCIE 811
Query: 192 GPPGPQGPPGI------------------PGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
GP G QG PG+ PGIPG+ + G G PG PG QG G G
Sbjct: 812 GPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871
Query: 234 PSGAADKAG 242
G G
Sbjct: 872 QRGYPGNPG 880
Score = 61.2 bits (147), Expect = 2e-09
Identities = 37/81 (45%), Positives = 42/81 (51%), Gaps = 8/81 (9%)
Query: 182 PGPNGPPGPPGP------PGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
PGP G PG PG PG QG G+ G PG PG T G PG PG PG QG PGL+G
Sbjct: 483 PGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNT--GLPGFPGFPGAQGDPGLKGEK 540
Query: 236 GAADKAGTRENQPAVVHLQGQ 256
G + + P L+GQ
Sbjct: 541 GETLQPEGQVGVPGDPGLRGQ 561
Score = 58.5 bits (140), Expect = 1e-08
Identities = 53/172 (30%), Positives = 60/172 (34%), Gaps = 15/172 (8%)
Query: 79 GGSGTPGTSGTLSSLGGLDPD--SPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G GTPG G G P S + G+P K PGE L
Sbjct: 925 GQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLK 984
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
P P R + S N G G G PG G G G PG
Sbjct: 985 GLPGPAGPPGP-------RGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGR 1037
Query: 197 QGPPGIPGIPGI------PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG+PGI G+ PG + PGPPGP G G PG G G + G
Sbjct: 1038 AGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPG 1089
Score = 57.4 bits (137), Expect = 2e-08
Identities = 32/70 (45%), Positives = 36/70 (51%), Gaps = 1/70 (1%)
Query: 175 KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQG 233
KG+K P G G PG PG +G PG G+ GIPGT V G PGP G G G QG
Sbjct: 537 KGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQG 596
Query: 234 PSGAADKAGT 243
P G G+
Sbjct: 597 PPGDPGSPGS 606
Score = 54.3 bits (129), Expect = 2e-07
Identities = 64/230 (27%), Positives = 80/230 (34%), Gaps = 40/230 (17%)
Query: 66 SELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSP---ITSHLGQPSPKQQPLEPGEAA 122
S+ R R + +G G+PG +G+ G P P I G P P G
Sbjct: 402 SKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPG 461
Query: 123 LHS-DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ D G L P + K +GA G + G
Sbjct: 462 IPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGL 521
Query: 182 PGPNGPPGPPGPPG----------PQGPPGIPGIP------------GIPGTT-VMGPPG 218
PG G PG G PG P+G G+PG P GIPGT V G PG
Sbjct: 522 PGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPG 581
Query: 219 P------------PGPPGPQGPPGLQGPSGAADKAG-TRENQPAVVHLQG 255
P GPPG G PG GP+G A G + +P + QG
Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQG 631
Score = 51.6 bits (122), Expect = 1e-06
Identities = 34/81 (41%), Positives = 36/81 (44%), Gaps = 18/81 (22%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGI---PGIPGTTVM----GPP-----------GPPG 221
GP G G PG G G QG PG+PG PGIPG + G P G PG
Sbjct: 115 GPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPG 174
Query: 222 PPGPQGPPGLQGPSGAADKAG 242
PG GP GL GP G G
Sbjct: 175 LPGAPGPQGLPGPPGFPGPVG 195
Score = 48.1 bits (113), Expect = 1e-05
Identities = 25/53 (47%), Positives = 26/53 (49%), Gaps = 2/53 (3%)
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G G +G G PG PG PG G GP G PGPQGP G G G G R
Sbjct: 43 GAKGEKGEKGFPGPPGSPGQK--GFTGPEGLPGPQGPKGFPGLPGLTGSKGVR 93
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 89.4 bits (220), Expect = 5e-18
Identities = 70/202 (34%), Positives = 85/202 (42%), Gaps = 26/202 (12%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R E+G G G PG +G G P G P P PG + + +
Sbjct: 598 RGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP-QGEKGDVGPAGPPGVPG-SVVQQEGL 655
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKK-KGKKA--GPPG-- 183
G Q A P + + + EG DGP + +GKK GPPG
Sbjct: 656 KGEQGA--------PGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIP 707
Query: 184 -------PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
P GPPG PGPPGP G PG+PG G PG GPPGP GPPG GP G GP G
Sbjct: 708 GLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKP--GPPGPTGPPGKDGPNGPPGPPG 765
Query: 237 AADKAGTR--ENQPAVVHLQGQ 256
+ G R + P L+G+
Sbjct: 766 TKGEPGERGEDGLPGKPGLRGE 787
Score = 85.5 bits (210), Expect = 8e-17
Identities = 43/79 (54%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Query: 165 GADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPP 223
G GP AGPPG G PG GPPGPQGP G+PGIPG G G PGPPG P
Sbjct: 1198 GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP 1257
Query: 224 GPQGPPGLQGPSGAADKAG 242
G G PGL GP GA G
Sbjct: 1258 GKAGEPGLPGPEGARGPPG 1276
Score = 81.6 bits (200), Expect = 1e-15
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 15/180 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----Q 128
G + G G PG G S L G+ + G+P P +P + GE L
Sbjct: 1216 GIQGSPGKEGPPGPQGP-SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 1274
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G + + P P E + + + +G GP + GPPG NG P
Sbjct: 1275 PGFKGHTGDSGAPG--PRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332
Query: 189 GPPGPPGPQGPPGIP------GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PGP G PG G PG+PG +GP GPPG PG +G PG +G G + G
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGSPGLPG--FLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 1390
Score = 78.6 bits (192), Expect = 9e-15
Identities = 66/199 (33%), Positives = 79/199 (39%), Gaps = 37/199 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G + G G PGT G G GL + +G+ +P E GEA L
Sbjct: 753 GKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG-- 810
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKAGPPGPNGPPG 189
FP VR K + +G G P +G+K G GP GPPG
Sbjct: 811 ---------FPG-----------VRGEKGDQGEKGELGLPGLKGDRGEK-GEAGPAGPPG 849
Query: 190 PPGP----------PGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAA 238
PG PG QGP G G PG+PG + G PG GP GP GPPG +G GA
Sbjct: 850 LPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAH 909
Query: 239 DKAGTRENQPAVVHLQGQG 257
G N A H+ G
Sbjct: 910 GAPGAAGNPGAPGHVGAPG 928
Score = 77.8 bits (190), Expect = 2e-14
Identities = 68/207 (32%), Positives = 82/207 (39%), Gaps = 55/207 (26%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH-SDSQDGH 131
GA+ + G G PG +G +P +P H+G P P P G L + +DG
Sbjct: 901 GAKGQEGAHGAPGAAG--------NPGAP--GHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ EK + EE R + GA G KGK G PG G PG P
Sbjct: 951 R---------GEKGAAGEEGSPGPVGPRG--DPGAPGLPGPPGKGKD-GEPGLRGSPGLP 998
Query: 192 GP-----------------------PGPQGPPGIPGIPGI---PGTTVMGPPGPPGPPGP 225
GP G +G PGIPG PG PG V GPPGP GPPG
Sbjct: 999 GPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGD 1058
Query: 226 QGP------PGLQGPSGAADKAGTREN 246
+G PG GP G A + G N
Sbjct: 1059 KGSPGSRGLPGFPGPQGPAGRDGAPGN 1085
Score = 74.3 bits (181), Expect = 2e-13
Identities = 62/188 (32%), Positives = 75/188 (39%), Gaps = 34/188 (18%)
Query: 79 GGSGTPGTSGTLSSLG-----GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQM 133
G SG PG G+ S G G + G P + P +PG ++L S +
Sbjct: 1051 GPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGD----I 1106
Query: 134 ALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP----- 188
LL ++ P + K K G G + K +AGPPG GPP
Sbjct: 1107 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGP 1166
Query: 189 -------------------GPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGP 228
G PG PG GPPG PG PG G GPPG G PG +GP
Sbjct: 1167 QGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 1226
Query: 229 PGLQGPSG 236
PG QGPSG
Sbjct: 1227 PGPQGPSG 1234
Score = 74.3 bits (181), Expect = 2e-13
Identities = 64/195 (32%), Positives = 71/195 (36%), Gaps = 28/195 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSD 126
R E GA G G PG G G P P G P +P G
Sbjct: 1290 RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 1349
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L F P P E K EG G K G PG G
Sbjct: 1350 KGENGSPGLPGFLGPRGPPGEPGE-------KGVPGKEGVPG---------KPGEPGFKG 1393
Query: 187 PPGPPGPPGPQGPP---GIPGIPGIPG----TTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
G PG G +GPP G PG PGIPG T +MGP G PG GP GPP GP G
Sbjct: 1394 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP---GPPGQPG 1450
Query: 240 KAGTRENQPAVVHLQ 254
G R P++ L+
Sbjct: 1451 FPGLRGESPSMETLR 1465
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/200 (31%), Positives = 78/200 (39%), Gaps = 35/200 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
+G + GG G PG G G GL + G P P +PG L +S
Sbjct: 1401 KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPS 1460
Query: 130 ------------GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE----GADGPVKNK 173
G Q+ + + P + +S + R + G GP+
Sbjct: 1461 METLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP 1520
Query: 174 KKGKKAGPPGPNGPPGP---------PGPPG-----PQGPPGIPGIPGIPGTTVMGPPGP 219
+ + G GP+GP GP PG PG GPPGIPG PG PG G PG
Sbjct: 1521 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1580
Query: 220 PGPPGPQGP---PGLQGPSG 236
PGP G GP PGL GP G
Sbjct: 1581 PGPQGETGPAGHPGLPGPPG 1600
Score = 72.4 bits (176), Expect = 7e-13
Identities = 60/202 (29%), Positives = 72/202 (35%), Gaps = 52/202 (25%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
L+ +RG + G +G PG GT S P + G K P PGE L
Sbjct: 832 LKGDRGEKGEAGPAGPPGLPGTTSLF---TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRP 888
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+ L P P + K + GA G N G PGP+GP
Sbjct: 889 GE------LGPQGPTGPPGA----------KGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 932
Query: 188 PGP---------------------------PGPPGPQGPPGIPGIPGIPGTTVMGPPGPP 220
PG PGP GP+G PG PG+PG PG G
Sbjct: 933 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG------KGKD 986
Query: 221 GPPGPQGPPGLQGPSGAADKAG 242
G PG +G PGL GP G G
Sbjct: 987 GEPGLRGSPGLPGPLGTKAACG 1008
Score = 70.9 bits (172), Expect = 2e-12
Identities = 71/245 (28%), Positives = 87/245 (35%), Gaps = 45/245 (18%)
Query: 20 RGSQGC-GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRERGAESRL 78
RG G G G P + +G L G GL L C ++R G +
Sbjct: 969 RGDPGAPGLPGPPGKGKDGEPGLR--GSPGLPGPLGTKAACG--KVRGSENCALGGQCVK 1024
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G G PG G+ S G DP + G P PG L
Sbjct: 1025 GDRGAPGIPGSPGSRG--DPGIGVAGPPGPSGPPGDKGSPGSRGLPG------------- 1069
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG------------PNG 186
FP + + + + N G GP P P G
Sbjct: 1070 -FPGPQGPAGRDG--------APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPG 1120
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
PPG PG PG +G G+PG PG GT GPPG PGPPG GP G QG GA + G
Sbjct: 1121 PPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVG 1180
Query: 243 TRENQ 247
+ +Q
Sbjct: 1181 QKGDQ 1185
Score = 70.1 bits (170), Expect = 3e-12
Identities = 59/203 (29%), Positives = 77/203 (37%), Gaps = 34/203 (16%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
E+G + LG G PG G+ G G + + +G P+ P PG
Sbjct: 528 EKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPG--RVGA 585
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G Q E + R K + +G G + + + GP G GP
Sbjct: 586 PGLQ--------------GERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQ 631
Query: 189 GPPGPPGPQGPPGIPGI----------PGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGA 237
G G GP GPPG+PG G PG G PGPPG GP GP G GP G
Sbjct: 632 GEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGL 691
Query: 238 ADKAGTRENQ-----PAVVHLQG 255
G + + P ++ LQG
Sbjct: 692 QGLRGKKGDMGPPGIPGLLGLQG 714
Score = 68.9 bits (167), Expect = 7e-12
Identities = 58/188 (30%), Positives = 71/188 (37%), Gaps = 17/188 (9%)
Query: 64 LRSELRRE--RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEA 121
LR E+ + G G +G PG G + G D LG P K E GEA
Sbjct: 784 LRGEIGEQGLAGRPGEKGEAGLPGAPG-FPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842
Query: 122 ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
+ + F P + E+ K K + G G + + + GP
Sbjct: 843 G---PAGPPGLPGTTSLFTPHPRMPGEQGP------KGEKGDPGLPGEPGLQGRPGELGP 893
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
GP GPPG G G G PG G PG PG G PGP GP G G G G K
Sbjct: 894 QGPTGPPGAKGQEGAHGAPGAAGNPGAPGHV-----GAPGPSGPPGSVGAPGLRGTPGKD 948
Query: 242 GTRENQPA 249
G R + A
Sbjct: 949 GERGEKGA 956
Score = 68.2 bits (165), Expect = 1e-11
Identities = 61/204 (29%), Positives = 77/204 (37%), Gaps = 44/204 (21%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E+G G G PG G + ++G +G P PK E G+ + Q G
Sbjct: 482 EKGEMGVAGPMGLPGPKGDIGAIG----------PVGAPGPKG---EKGDVGIGPFGQ-G 527
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+ + P P + S+ +R G G V G GP GPPG
Sbjct: 528 EKGEKGSLGLPG--PPGRDGSKGMRGEPGELGEPGLPGEV---------GMRGPQGPPGL 576
Query: 191 PGPPGPQGPP------------------GIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGL 231
PGPPG G P G+ G PG PG T G PGP G GPQG G
Sbjct: 577 PGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGD 636
Query: 232 QGPSGAADKAGTRENQPAVVHLQG 255
GP+G G+ Q + QG
Sbjct: 637 VGPAGPPGVPGSVVQQEGLKGEQG 660
Score = 68.2 bits (165), Expect = 1e-11
Identities = 35/65 (53%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 178 KAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGA 237
K GPPGP GPPG GP GP GPPG G PG G G PG PG G G GL G G
Sbjct: 742 KPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED--GLPGKPGLRGEIGEQGLAGRPGE 799
Query: 238 ADKAG 242
+AG
Sbjct: 800 KGEAG 804
Score = 66.6 bits (161), Expect = 4e-11
Identities = 68/241 (28%), Positives = 85/241 (35%), Gaps = 77/241 (31%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
ERG + G G+PG G G GL P P G+P + P PG L + +
Sbjct: 950 ERGEKGAAGEEGSPGPVGPRGDPGAPGL-PGPPGKGKDGEPGLRGSPGLPGP--LGTKAA 1006
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G N + + + + + S+ + G AGPPGP+GPP
Sbjct: 1007 CGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIG----------VAGPPGPSGPP 1056
Query: 189 GP---------PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPG------------------ 221
G PG PGPQGP G G PG PG GPPG PG
Sbjct: 1057 GDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGER--GPPGKPGLSSLLSPGDINLLAKDVC 1114
Query: 222 ---PPGPQG------------------------------PPGLQGPSGAADKAGTRENQP 248
PPGP G PPGL GP G A G++ +
Sbjct: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
Query: 249 A 249
A
Sbjct: 1175 A 1175
Score = 66.2 bits (160), Expect = 5e-11
Identities = 33/63 (52%), Positives = 36/63 (57%), Gaps = 2/63 (3%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
G PGP GP GPPG GP GPPG PG G PG G G PG PG +G G QG +G
Sbjct: 741 GKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGE--RGEDGLPGKPGLRGEIGEQGLAGRPG 798
Query: 240 KAG 242
+ G
Sbjct: 799 EKG 801
Score = 65.9 bits (159), Expect = 6e-11
Identities = 62/224 (27%), Positives = 75/224 (33%), Gaps = 67/224 (29%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+ G SGTPG G+ G P P G P+ P EPGE + +
Sbjct: 1333 GSPGEPGPSGTPGQKGSKGENGS--PGLP-----GFLGPRGPPGEPGEKGVPGKEGVPGK 1385
Query: 133 MALLNFFFPDEKPYSEEESRR-VRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P E + E ++ +K +G G G GP G PG
Sbjct: 1386 --------PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN 1437
Query: 192 GPPGPQGPPGIPGIPGIPGTTV------------------------------------MG 215
GP GP GPPG PG PG+ G + G
Sbjct: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497
Query: 216 PPGPPGPPGPQGPPG---------------LQGPSGAADKAGTR 244
PGPPGPPG G PG L+GPSG G R
Sbjct: 1498 RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 1541
Score = 64.7 bits (156), Expect = 1e-10
Identities = 59/205 (28%), Positives = 77/205 (37%), Gaps = 42/205 (20%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + +G +G G G +G + P +G P PK E G+ + Q G +
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAIGP-------VGAPGPKG---EKGDVGIGPFGQ-GEK 529
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ P P + S+ +R G G V G GP GPPG PG
Sbjct: 530 GEKGSLGLPG--PPGRDGSKGMRGEPGELGEPGLPGEV---------GMRGPQGPPGLPG 578
Query: 193 PPGPQGPPGIPG------------------IPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
PPG G PG+ G PG PG T G G PGP G GP G +G
Sbjct: 579 PPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDT--GQQGRPGPSGVAGPQGEKGD 636
Query: 235 SGAADKAGTRENQPAVVHLQGQGSA 259
G A G + L+G+ A
Sbjct: 637 VGPAGPPGVPGSVVQQEGLKGEQGA 661
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/123 (35%), Positives = 48/123 (39%), Gaps = 50/123 (40%)
Query: 169 PVKNKKKGKKAGPPGPNGP------------PGP-------------------------P 191
P K + AGP G GP PGP P
Sbjct: 479 PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLP 538
Query: 192 GPP------GPQGPPGIPGIPGIPGTTVM----GPPGPPGPPGPQGPPGLQGPSGAADKA 241
GPP G +G PG G PG+PG M GPPG PGPPG G PGLQG G +
Sbjct: 539 GPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERG---EK 595
Query: 242 GTR 244
GTR
Sbjct: 596 GTR 598
Score = 38.5 bits (88), Expect = 0.011
Identities = 56/210 (26%), Positives = 69/210 (32%), Gaps = 19/210 (9%)
Query: 13 PAAAPRERGSQGC----GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSEL 68
P P E G G G G P GE S L L T YL +
Sbjct: 1430 PQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 1489
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEP-GEAALHSD 126
+ ++ R G G PG G G + +P P L PS P+ P GE D
Sbjct: 1490 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG---PIGPKGERGAKGD 1546
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P P E + +G G + + AG PG G
Sbjct: 1547 P-GAPGVGLRGEMGPPGIPGQPGEP--------GYAKDGLPGIPGPQGETGPAGHPGLPG 1597
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTTVMGP 216
PPGPPG P + PG V GP
Sbjct: 1598 PPGPPGQCDPSQCAYFASLAARPG-NVKGP 1626
Score = 37.0 bits (84), Expect = 0.031
Identities = 24/61 (39%), Positives = 26/61 (42%), Gaps = 8/61 (13%)
Query: 184 PNGP------PGPPGPPGPQGPP--GIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
P+GP PP PP PQ PP G I + P G G G GP GL GP
Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498
Query: 236 G 236
G
Sbjct: 499 G 499
>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
sapiens]
Length = 1751
Score = 88.6 bits (218), Expect = 9e-18
Identities = 51/128 (39%), Positives = 63/128 (49%), Gaps = 15/128 (11%)
Query: 165 GADGPVKNKKKGKKAGPPGPNGPPG--------PPGPPGPQGPPGIPGIPGIPGTTVMGP 216
G GP +G+ GPPGP GPPG PPGPPGP GPP PG P +
Sbjct: 1366 GIPGPKGESIRGQP-GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG----PHRQTISV 1420
Query: 217 PGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQV--KNDLSGGVLNDW 274
PGPPGPPGP GPPG G S TR+ VH +G I V + +L V N +
Sbjct: 1421 PGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGF 1480
Query: 275 SRITMNPK 282
++ + +
Sbjct: 1481 RKVQLEAR 1488
Score = 81.6 bits (200), Expect = 1e-15
Identities = 62/202 (30%), Positives = 78/202 (38%), Gaps = 55/202 (27%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G G G PGT G + G D P G P P+ P PG + H
Sbjct: 827 EDGKPGDTGPQGFPGTPGDVGPKG--DKGDPGVGERGPPGPQGPPGPPGPSFRH------ 878
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
D+ + + E G G ++ + GP G PGP
Sbjct: 879 -----------DKLTFIDMEG------------SGFGGDLEALR--------GPRGFPGP 907
Query: 191 PGPPGPQGPPGIP--------------GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PGPPG G PG P G+PG+PG GPPG PG PGP GPPG +GP G
Sbjct: 908 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE--GPPGFPGLPGPPGPPGREGPPG 965
Query: 237 AADKAGTRENQPAVVHLQGQGS 258
+ G+ A H +G+
Sbjct: 966 RTGQKGSLGEAGAPGHKGSKGA 987
Score = 78.6 bits (192), Expect = 9e-15
Identities = 70/232 (30%), Positives = 86/232 (37%), Gaps = 54/232 (23%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH-------------LGQPSPKQQPLEPG 119
GA+ +G G PG G G P P +GQP P PG
Sbjct: 1066 GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG 1125
Query: 120 EAALHSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNK---- 173
S+ QDG ++L+ P+ +P + N SK G+ GP K
Sbjct: 1126 PVVYVSE-QDG---SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 1181
Query: 174 -------------KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-------- 212
+KG K G PG GPPGP G PG +G G PG PG PG
Sbjct: 1182 SIFSPDGGALGPAQKGAK-GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE 1240
Query: 213 ---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
+ G PGPPGPPGP GPPG +R P + QG
Sbjct: 1241 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 1292
Score = 78.6 bits (192), Expect = 9e-15
Identities = 65/205 (31%), Positives = 77/205 (37%), Gaps = 44/205 (21%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH 124
R + E G R G G G G G + G P P P PG
Sbjct: 1213 RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1272
Query: 125 SDSQDGHQMALLNFFFPDEKPYSE--EESRRVRRNKRSKSNEGADGP----------VKN 172
S N F +P ++ K +K G GP ++
Sbjct: 1273 S-----------NVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 1321
Query: 173 KKKGKK-----AGPPGPNGPPGP--------PGPPGPQGPPGIPGIPGIPGTTVMGPPGP 219
+ KG+K AG G G PG PGPPGP GP G PGIPG G ++ G PGP
Sbjct: 1322 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGP 1381
Query: 220 PGPPGP--------QGPPGLQGPSG 236
PGP GP QGPPG GP G
Sbjct: 1382 PGPQGPPGIGYEGRQGPPGPPGPPG 1406
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/181 (34%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G E R G +G PG +G +LG G P PK + EPG S DG
Sbjct: 1142 GPEGRPGFAGFPGPAGPKGNLGS-------KGERGSPGPKGEKGEPGSIF----SPDGGA 1190
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADG-PVKNKKKGKKAGPP------GP 184
+ E + R + + G G P N KG+K P G
Sbjct: 1191 LGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGM 1250
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGP---PGPPGPPGPQGPPGLQGPSGAADKA 241
G PGPPGPPGP GPPG P + + V PGPPG PG QGPPG +G G
Sbjct: 1251 RGMPGPPGPPGPPGPPGTP----VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPP 1306
Query: 242 G 242
G
Sbjct: 1307 G 1307
Score = 77.0 bits (188), Expect = 3e-14
Identities = 54/162 (33%), Positives = 63/162 (38%), Gaps = 6/162 (3%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG----EAALHSDSQDGHQMA 134
G G PG G G DS + + +P P P G + A G
Sbjct: 1252 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQ 1311
Query: 135 LLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPP 194
F E E+ R ++ + E G GPPGP G PG PGP
Sbjct: 1312 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 1371
Query: 195 GP--QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
G +G PG PG G PG G GPPGPPGP GPP GP
Sbjct: 1372 GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP 1413
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/91 (43%), Positives = 49/91 (53%), Gaps = 9/91 (9%)
Query: 161 KSNEGADGPVKNKKKGKKAGPPGPNGPPGPP---GPPGPQGPPGIPGIPGIPG------T 211
K ++GA GP + + AG PGP GPPGPP GPPGP P G + G G
Sbjct: 982 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 1041
Query: 212 TVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
+ GP GPPG PG +G PG+ G GA + G
Sbjct: 1042 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 1072
Score = 72.4 bits (176), Expect = 7e-13
Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 16/92 (17%)
Query: 167 DGPVKNKK-KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--------------- 210
DG V+ + K+ G G G PG PGPPG GPPG P +PG PG
Sbjct: 738 DGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPAL 797
Query: 211 TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
TV GP GPPGPPG G PG G G + G
Sbjct: 798 QTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 829
Score = 69.3 bits (168), Expect = 6e-12
Identities = 43/88 (48%), Positives = 43/88 (48%), Gaps = 26/88 (29%)
Query: 179 AGP-----PGPNGPPGPPG---PPGPQGPPGIPGIPGIPGTT-VMGPPGPPG-------- 221
AGP PGP GPPGPPG PG G PG PG G PG T G PG PG
Sbjct: 793 AGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 852
Query: 222 ---------PPGPQGPPGLQGPSGAADK 240
PPGPQGPPG GPS DK
Sbjct: 853 GDPGVGERGPPGPQGPPGPPGPSFRHDK 880
Score = 64.7 bits (156), Expect = 1e-10
Identities = 36/74 (48%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 180 GPPGPN-----GPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
GP GP GP GPPGPPG G PG G PG PG G PG GP G G PG GP
Sbjct: 791 GPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED--GKPGDTGPQGFPGTPGDVGP 848
Query: 235 SGAADKAGTRENQP 248
G G E P
Sbjct: 849 KGDKGDPGVGERGP 862
Score = 63.9 bits (154), Expect = 2e-10
Identities = 33/71 (46%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGI------PGIPGTTVMGPP 217
+G GP + G PG G G PG GPQG PG PG G PG GPP
Sbjct: 804 QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPP 863
Query: 218 GPPGPPGPQGP 228
GP GPPGP GP
Sbjct: 864 GPQGPPGPPGP 874
Score = 30.0 bits (66), Expect = 3.7
Identities = 24/70 (34%), Positives = 26/70 (37%), Gaps = 2/70 (2%)
Query: 194 PGPQGPPGIPGIPGIPGTTVM--GPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PG G PG V G G G PG GPPG GP G+ G V
Sbjct: 729 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS 788
Query: 252 HLQGQGSAIQ 261
L G A+Q
Sbjct: 789 PLGPAGPALQ 798
Score = 28.9 bits (63), Expect = 8.3
Identities = 24/71 (33%), Positives = 25/71 (35%), Gaps = 11/71 (15%)
Query: 181 PPGPNGPPGPPGPPGPQGPP-----GIPGIPGI----PGTTVMGPPGPPGPPGPQGPPGL 231
P GP GP P G GIP PG GT P PP P P L
Sbjct: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP--L 205
Query: 232 QGPSGAADKAG 242
GPS +G
Sbjct: 206 TGPSVPPPSSG 216
>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
sapiens]
Length = 1336
Score = 88.6 bits (218), Expect = 9e-18
Identities = 51/128 (39%), Positives = 63/128 (49%), Gaps = 15/128 (11%)
Query: 165 GADGPVKNKKKGKKAGPPGPNGPPG--------PPGPPGPQGPPGIPGIPGIPGTTVMGP 216
G GP +G+ GPPGP GPPG PPGPPGP GPP PG P +
Sbjct: 951 GIPGPKGESIRGQP-GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG----PHRQTISV 1005
Query: 217 PGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQV--KNDLSGGVLNDW 274
PGPPGPPGP GPPG G S TR+ VH +G I V + +L V N +
Sbjct: 1006 PGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGF 1065
Query: 275 SRITMNPK 282
++ + +
Sbjct: 1066 RKVQLEAR 1073
Score = 81.6 bits (200), Expect = 1e-15
Identities = 62/202 (30%), Positives = 78/202 (38%), Gaps = 55/202 (27%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G G G PGT G + G D P G P P+ P PG + H
Sbjct: 412 EDGKPGDTGPQGFPGTPGDVGPKG--DKGDPGVGERGPPGPQGPPGPPGPSFRH------ 463
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
D+ + + E G G ++ + GP G PGP
Sbjct: 464 -----------DKLTFIDMEG------------SGFGGDLEALR--------GPRGFPGP 492
Query: 191 PGPPGPQGPPGIP--------------GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PGPPG G PG P G+PG+PG GPPG PG PGP GPPG +GP G
Sbjct: 493 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE--GPPGFPGLPGPPGPPGREGPPG 550
Query: 237 AADKAGTRENQPAVVHLQGQGS 258
+ G+ A H +G+
Sbjct: 551 RTGQKGSLGEAGAPGHKGSKGA 572
Score = 78.6 bits (192), Expect = 9e-15
Identities = 70/232 (30%), Positives = 86/232 (37%), Gaps = 54/232 (23%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH-------------LGQPSPKQQPLEPG 119
GA+ +G G PG G G P P +GQP P PG
Sbjct: 651 GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG 710
Query: 120 EAALHSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNK---- 173
S+ QDG ++L+ P+ +P + N SK G+ GP K
Sbjct: 711 PVVYVSE-QDG---SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766
Query: 174 -------------KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-------- 212
+KG K G PG GPPGP G PG +G G PG PG PG
Sbjct: 767 SIFSPDGGALGPAQKGAK-GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE 825
Query: 213 ---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
+ G PGPPGPPGP GPPG +R P + QG
Sbjct: 826 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 877
Score = 78.6 bits (192), Expect = 9e-15
Identities = 65/205 (31%), Positives = 77/205 (37%), Gaps = 44/205 (21%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH 124
R + E G R G G G G G + G P P P PG
Sbjct: 798 RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 857
Query: 125 SDSQDGHQMALLNFFFPDEKPYSE--EESRRVRRNKRSKSNEGADGP----------VKN 172
S N F +P ++ K +K G GP ++
Sbjct: 858 S-----------NVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 906
Query: 173 KKKGKK-----AGPPGPNGPPGP--------PGPPGPQGPPGIPGIPGIPGTTVMGPPGP 219
+ KG+K AG G G PG PGPPGP GP G PGIPG G ++ G PGP
Sbjct: 907 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGP 966
Query: 220 PGPPGP--------QGPPGLQGPSG 236
PGP GP QGPPG GP G
Sbjct: 967 PGPQGPPGIGYEGRQGPPGPPGPPG 991
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/181 (34%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G E R G +G PG +G +LG G P PK + EPG S DG
Sbjct: 727 GPEGRPGFAGFPGPAGPKGNLGS-------KGERGSPGPKGEKGEPGSIF----SPDGGA 775
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADG-PVKNKKKGKKAGPP------GP 184
+ E + R + + G G P N KG+K P G
Sbjct: 776 LGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGM 835
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGP---PGPPGPPGPQGPPGLQGPSGAADKA 241
G PGPPGPPGP GPPG P + + V PGPPG PG QGPPG +G G
Sbjct: 836 RGMPGPPGPPGPPGPPGTP----VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPP 891
Query: 242 G 242
G
Sbjct: 892 G 892
Score = 77.0 bits (188), Expect = 3e-14
Identities = 54/162 (33%), Positives = 63/162 (38%), Gaps = 6/162 (3%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG----EAALHSDSQDGHQMA 134
G G PG G G DS + + +P P P G + A G
Sbjct: 837 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQ 896
Query: 135 LLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPP 194
F E E+ R ++ + E G GPPGP G PG PGP
Sbjct: 897 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 956
Query: 195 GP--QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
G +G PG PG G PG G GPPGPPGP GPP GP
Sbjct: 957 GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP 998
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/91 (43%), Positives = 49/91 (53%), Gaps = 9/91 (9%)
Query: 161 KSNEGADGPVKNKKKGKKAGPPGPNGPPGPP---GPPGPQGPPGIPGIPGIPG------T 211
K ++GA GP + + AG PGP GPPGPP GPPGP P G + G G
Sbjct: 567 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 626
Query: 212 TVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
+ GP GPPG PG +G PG+ G GA + G
Sbjct: 627 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 657
Score = 72.4 bits (176), Expect = 7e-13
Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 16/92 (17%)
Query: 167 DGPVKNKK-KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--------------- 210
DG V+ + K+ G G G PG PGPPG GPPG P +PG PG
Sbjct: 323 DGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPAL 382
Query: 211 TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
TV GP GPPGPPG G PG G G + G
Sbjct: 383 QTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 414
Score = 69.3 bits (168), Expect = 6e-12
Identities = 43/88 (48%), Positives = 43/88 (48%), Gaps = 26/88 (29%)
Query: 179 AGP-----PGPNGPPGPPG---PPGPQGPPGIPGIPGIPGTT-VMGPPGPPG-------- 221
AGP PGP GPPGPPG PG G PG PG G PG T G PG PG
Sbjct: 378 AGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 437
Query: 222 ---------PPGPQGPPGLQGPSGAADK 240
PPGPQGPPG GPS DK
Sbjct: 438 GDPGVGERGPPGPQGPPGPPGPSFRHDK 465
Score = 64.7 bits (156), Expect = 1e-10
Identities = 36/74 (48%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 180 GPPGPN-----GPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
GP GP GP GPPGPPG G PG G PG PG G PG GP G G PG GP
Sbjct: 376 GPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED--GKPGDTGPQGFPGTPGDVGP 433
Query: 235 SGAADKAGTRENQP 248
G G E P
Sbjct: 434 KGDKGDPGVGERGP 447
Score = 63.9 bits (154), Expect = 2e-10
Identities = 33/71 (46%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGI------PGIPGTTVMGPP 217
+G GP + G PG G G PG GPQG PG PG G PG GPP
Sbjct: 389 QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPP 448
Query: 218 GPPGPPGPQGP 228
GP GPPGP GP
Sbjct: 449 GPQGPPGPPGP 459
Score = 30.0 bits (66), Expect = 3.7
Identities = 24/70 (34%), Positives = 26/70 (37%), Gaps = 2/70 (2%)
Query: 194 PGPQGPPGIPGIPGIPGTTVM--GPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PG G PG V G G G PG GPPG GP G+ G V
Sbjct: 314 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS 373
Query: 252 HLQGQGSAIQ 261
L G A+Q
Sbjct: 374 PLGPAGPALQ 383
>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
sapiens]
Length = 1516
Score = 88.6 bits (218), Expect = 9e-18
Identities = 51/128 (39%), Positives = 63/128 (49%), Gaps = 15/128 (11%)
Query: 165 GADGPVKNKKKGKKAGPPGPNGPPG--------PPGPPGPQGPPGIPGIPGIPGTTVMGP 216
G GP +G+ GPPGP GPPG PPGPPGP GPP PG P +
Sbjct: 1131 GIPGPKGESIRGQP-GPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPG----PHRQTISV 1185
Query: 217 PGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQV--KNDLSGGVLNDW 274
PGPPGPPGP GPPG G S TR+ VH +G I V + +L V N +
Sbjct: 1186 PGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGF 1245
Query: 275 SRITMNPK 282
++ + +
Sbjct: 1246 RKVQLEAR 1253
Score = 81.6 bits (200), Expect = 1e-15
Identities = 62/202 (30%), Positives = 78/202 (38%), Gaps = 55/202 (27%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G G G PGT G + G D P G P P+ P PG + H
Sbjct: 592 EDGKPGDTGPQGFPGTPGDVGPKG--DKGDPGVGERGPPGPQGPPGPPGPSFRH------ 643
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
D+ + + E G G ++ + GP G PGP
Sbjct: 644 -----------DKLTFIDMEG------------SGFGGDLEALR--------GPRGFPGP 672
Query: 191 PGPPGPQGPPGIP--------------GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PGPPG G PG P G+PG+PG GPPG PG PGP GPPG +GP G
Sbjct: 673 PGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGRE--GPPGFPGLPGPPGPPGREGPPG 730
Query: 237 AADKAGTRENQPAVVHLQGQGS 258
+ G+ A H +G+
Sbjct: 731 RTGQKGSLGEAGAPGHKGSKGA 752
Score = 78.6 bits (192), Expect = 9e-15
Identities = 70/232 (30%), Positives = 86/232 (37%), Gaps = 54/232 (23%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH-------------LGQPSPKQQPLEPG 119
GA+ +G G PG G G P P +GQP P PG
Sbjct: 831 GAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPG 890
Query: 120 EAALHSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNK---- 173
S+ QDG ++L+ P+ +P + N SK G+ GP K
Sbjct: 891 PVVYVSE-QDG---SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 946
Query: 174 -------------KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-------- 212
+KG K G PG GPPGP G PG +G G PG PG PG
Sbjct: 947 SIFSPDGGALGPAQKGAK-GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGE 1005
Query: 213 ---------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQG 255
+ G PGPPGPPGP GPPG +R P + QG
Sbjct: 1006 PGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQG 1057
Score = 78.6 bits (192), Expect = 9e-15
Identities = 65/205 (31%), Positives = 77/205 (37%), Gaps = 44/205 (21%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH 124
R + E G R G G G G G + G P P P PG
Sbjct: 978 RPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYD 1037
Query: 125 SDSQDGHQMALLNFFFPDEKPYSE--EESRRVRRNKRSKSNEGADGP----------VKN 172
S N F +P ++ K +K G GP ++
Sbjct: 1038 S-----------NVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEA 1086
Query: 173 KKKGKK-----AGPPGPNGPPGP--------PGPPGPQGPPGIPGIPGIPGTTVMGPPGP 219
+ KG+K AG G G PG PGPPGP GP G PGIPG G ++ G PGP
Sbjct: 1087 EMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGP 1146
Query: 220 PGPPGP--------QGPPGLQGPSG 236
PGP GP QGPPG GP G
Sbjct: 1147 PGPQGPPGIGYEGRQGPPGPPGPPG 1171
Score = 77.8 bits (190), Expect = 2e-14
Identities = 62/181 (34%), Positives = 74/181 (40%), Gaps = 26/181 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G E R G +G PG +G +LG G P PK + EPG S DG
Sbjct: 907 GPEGRPGFAGFPGPAGPKGNLGS-------KGERGSPGPKGEKGEPGSIF----SPDGGA 955
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADG-PVKNKKKGKKAGPP------GP 184
+ E + R + + G G P N KG+K P G
Sbjct: 956 LGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGM 1015
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGP---PGPPGPPGPQGPPGLQGPSGAADKA 241
G PGPPGPPGP GPPG P + + V PGPPG PG QGPPG +G G
Sbjct: 1016 RGMPGPPGPPGPPGPPGTP----VYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPP 1071
Query: 242 G 242
G
Sbjct: 1072 G 1072
Score = 77.0 bits (188), Expect = 3e-14
Identities = 54/162 (33%), Positives = 63/162 (38%), Gaps = 6/162 (3%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG----EAALHSDSQDGHQMA 134
G G PG G G DS + + +P P P G + A G
Sbjct: 1017 GMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQ 1076
Query: 135 LLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPP 194
F E E+ R ++ + E G GPPGP G PG PGP
Sbjct: 1077 FPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPK 1136
Query: 195 GP--QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
G +G PG PG G PG G GPPGPPGP GPP GP
Sbjct: 1137 GESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGP 1178
Score = 74.3 bits (181), Expect = 2e-13
Identities = 40/91 (43%), Positives = 49/91 (53%), Gaps = 9/91 (9%)
Query: 161 KSNEGADGPVKNKKKGKKAGPPGPNGPPGPP---GPPGPQGPPGIPGIPGIPG------T 211
K ++GA GP + + AG PGP GPPGPP GPPGP P G + G G
Sbjct: 747 KGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTAR 806
Query: 212 TVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
+ GP GPPG PG +G PG+ G GA + G
Sbjct: 807 SADGPQGPPGLPGLKGDPGVPGLPGAKGEVG 837
Score = 72.4 bits (176), Expect = 7e-13
Identities = 40/92 (43%), Positives = 45/92 (48%), Gaps = 16/92 (17%)
Query: 167 DGPVKNKK-KGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG--------------- 210
DG V+ + K+ G G G PG PGPPG GPPG P +PG PG
Sbjct: 503 DGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPAL 562
Query: 211 TTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
TV GP GPPGPPG G PG G G + G
Sbjct: 563 QTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDG 594
Score = 69.3 bits (168), Expect = 6e-12
Identities = 43/88 (48%), Positives = 43/88 (48%), Gaps = 26/88 (29%)
Query: 179 AGP-----PGPNGPPGPPG---PPGPQGPPGIPGIPGIPGTT-VMGPPGPPG-------- 221
AGP PGP GPPGPPG PG G PG PG G PG T G PG PG
Sbjct: 558 AGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDK 617
Query: 222 ---------PPGPQGPPGLQGPSGAADK 240
PPGPQGPPG GPS DK
Sbjct: 618 GDPGVGERGPPGPQGPPGPPGPSFRHDK 645
Score = 64.7 bits (156), Expect = 1e-10
Identities = 36/74 (48%), Positives = 36/74 (48%), Gaps = 7/74 (9%)
Query: 180 GPPGPN-----GPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGP 234
GP GP GP GPPGPPG G PG G PG PG G PG GP G G PG GP
Sbjct: 556 GPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGED--GKPGDTGPQGFPGTPGDVGP 613
Query: 235 SGAADKAGTRENQP 248
G G E P
Sbjct: 614 KGDKGDPGVGERGP 627
Score = 63.9 bits (154), Expect = 2e-10
Identities = 33/71 (46%), Positives = 35/71 (49%), Gaps = 6/71 (8%)
Query: 164 EGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGI------PGIPGTTVMGPP 217
+G GP + G PG G G PG GPQG PG PG G PG GPP
Sbjct: 569 QGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPP 628
Query: 218 GPPGPPGPQGP 228
GP GPPGP GP
Sbjct: 629 GPQGPPGPPGP 639
Score = 30.0 bits (66), Expect = 3.7
Identities = 24/70 (34%), Positives = 26/70 (37%), Gaps = 2/70 (2%)
Query: 194 PGPQGPPGIPGIPGIPGTTVM--GPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PG G PG V G G G PG GPPG GP G+ G V
Sbjct: 494 PGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS 553
Query: 252 HLQGQGSAIQ 261
L G A+Q
Sbjct: 554 PLGPAGPALQ 563
Score = 28.9 bits (63), Expect = 8.3
Identities = 27/91 (29%), Positives = 31/91 (34%), Gaps = 11/91 (12%)
Query: 181 PPGPNGPPGPPGPPGPQGPP-----GIPGIPGI----PGTTVMGPPGPPGPPGPQGPPGL 231
P GP GP P G GIP PG GT P PP P P L
Sbjct: 148 PVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAP--L 205
Query: 232 QGPSGAADKAGTRENQPAVVHLQGQGSAIQV 262
GPS + + ++ L G QV
Sbjct: 206 TGPSVPPPSSERISEEVGLLQLLGDPPPQQV 236
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/181 (34%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSDSQ 128
+RG G +G PG G + G P+ H G P P + PG A
Sbjct: 822 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 881
Query: 129 D-------GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
D G FP E+ K NEG GP + G
Sbjct: 882 DPGPPGAPGKDGPAGLRGFPGERGLPGTAG-----GPGLKGNEGPSGPPGPAGSPGERGA 936
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
G GP GPPG PGPQGPPG G G+PG GP GP G G QGP GL GP+G A
Sbjct: 937 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGE--KGPIGPTGRDGVQGPVGLPGPAGPPGVA 994
Query: 242 G 242
G
Sbjct: 995 G 995
Score = 85.5 bits (210), Expect = 8e-17
Identities = 67/202 (33%), Positives = 82/202 (40%), Gaps = 37/202 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + R G +G PG G + G L + + G+ PK PG S +
Sbjct: 686 GPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPGRQGPKGSLGFPG---FPGASGEKGA 741
Query: 133 MALLNFFFPDEK-----PYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
L P + P + R +K G DGP + G++ G PGP GP
Sbjct: 742 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP--HGPPGER-GLPGPQGP 798
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPP------------------GP 222
G PGP GP GPPG G+PG PG GPPGPP G
Sbjct: 799 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858
Query: 223 PGPQGPPGLQGPSGAADKAGTR 244
PGP GPPG QG G A K GT+
Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTK 880
Score = 85.1 bits (209), Expect = 1e-16
Identities = 60/174 (34%), Positives = 70/174 (40%), Gaps = 19/174 (10%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + +G G GT G G P PI +GQP EPG + G
Sbjct: 996 EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPG-----ARGPQG 1049
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
H A +E +R +G GP K + GP GP GPPGP
Sbjct: 1050 HFGA-----------KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP GP G G G PG G +GPPG G PG G PG+QG G G R
Sbjct: 1099 RGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1150
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/190 (34%), Positives = 79/190 (41%), Gaps = 15/190 (7%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+E R GG G G G + + G P P G+P P PG S Q G
Sbjct: 1241 GSEGRQGGKGAKGDPGAIGAPGKTGPVGP-AGPAGKPGPDGLRGLPG-----SVGQQGRP 1294
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
A P P +R + +K +G G + GPPG G G G
Sbjct: 1295 GATGQAGPPG--PVGPPGLPGLRGDAGAKGEKGHPGLIG------LIGPPGEQGEKGDRG 1346
Query: 193 PPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PGPQG PG G GIPG + +GP GPPG PGP GP G +G +G G + Q
Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406
Query: 252 HLQGQGSAIQ 261
H G IQ
Sbjct: 1407 HPGPPGEVIQ 1416
Score = 82.0 bits (201), Expect = 8e-16
Identities = 77/245 (31%), Positives = 91/245 (37%), Gaps = 18/245 (7%)
Query: 13 PAAAPRERGSQGC-GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRE 71
P E+G G G G P R G S L F GF G S L R E R
Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKGS-LGFPGFPGASGEKGARGLSGKSGPRGE-RGP 756
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH--------LGQPSPKQQPLEPGEAAL 123
G + G G G SG + GG P P G P PK P PG+ L
Sbjct: 757 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 816
Query: 124 HSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
++ P P + + + + G GP + AG
Sbjct: 817 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 876
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPG---IPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
G G PGPPG PG GP G+ G PG +PGT G PG G GP GPPG G G
Sbjct: 877 EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA--GGPGLKGNEGPSGPPGPAGSPGER 934
Query: 239 DKAGT 243
AG+
Sbjct: 935 GAAGS 939
Score = 79.7 bits (195), Expect = 4e-15
Identities = 61/183 (33%), Positives = 74/183 (40%), Gaps = 26/183 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G +G G PG SG G + P P G P P+ P P A D G
Sbjct: 1064 GPPGPIGLQGLPGPSGEKGETGDVGPMGPP----GPPGPRG-PAGPNGA----DGPQGPP 1114
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ N P EK E + + G GP + + ++G PG GPPGP G
Sbjct: 1115 GGVGNLGPPGEKGEPGESG-----SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1169
Query: 193 PPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG-------TRE 245
P G GP G PG G P G PGPPG GP+G G +G G + G T E
Sbjct: 1170 PTGDDGPKGNPGPVGFP-----GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1224
Query: 246 NQP 248
N P
Sbjct: 1225 NGP 1227
Score = 79.3 bits (194), Expect = 5e-15
Identities = 65/202 (32%), Positives = 82/202 (40%), Gaps = 32/202 (15%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSP---------------KQ 113
R E+G + G G PG G G P+ G P P +
Sbjct: 1150 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV-GFPGDPGPPGEGGPRGQDGAKGDRG 1208
Query: 114 QPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK 173
+ EPG+ + + L P P SE + K +K + GA G
Sbjct: 1209 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR----QGGKGAKGDPGAIGAPG-- 1262
Query: 174 KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
K GP GP GP G PGP G +G PG G G PG T G GPPGP GP G PGL+G
Sbjct: 1263 ----KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPVGPPGLPGLRG 1316
Query: 234 PSGAADKAGTRENQPAVVHLQG 255
+GA + G P ++ L G
Sbjct: 1317 DAGAKGEKG----HPGLIGLIG 1334
Score = 77.8 bits (190), Expect = 2e-14
Identities = 58/172 (33%), Positives = 65/172 (37%), Gaps = 46/172 (26%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG + +G G PG SG LG PK P PG + DG
Sbjct: 504 ERGDDGEIGPRGLPGESGPRGLLG----------------PKGPPGIPGPPGVRG--MDG 545
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
Q K S +G GP + G PGP G GP
Sbjct: 546 PQGP-----------------------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 582
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G GPQG PG+PG+PG GPPG PG GP G G QGPSG G
Sbjct: 583 HGEKGPQGKPGLPGMPGSD-----GPPGHPGKEGPPGTKGNQGPSGPQGPLG 629
Score = 77.0 bits (188), Expect = 3e-14
Identities = 66/214 (30%), Positives = 79/214 (36%), Gaps = 53/214 (24%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----- 127
G + G SG PG +G+ G PI G+P P+ P GE + +
Sbjct: 914 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP-GRPGPQGPPGAAGEKGVPGEKGPIGP 972
Query: 128 --QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+DG Q + P P V K G G K + GPPGP
Sbjct: 973 TGRDGVQ-GPVGLPGPAGPP-------GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024
Query: 186 GPPGP------------PGPPGPQ---------------GPPGIPGIPGIPGTT------ 212
GP GP PG GPQ GPPG G+ G+PG +
Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084
Query: 213 ----VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
MGPPGPPGP GP GP G GP G G
Sbjct: 1085 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1118
Score = 73.9 bits (180), Expect = 2e-13
Identities = 61/188 (32%), Positives = 68/188 (36%), Gaps = 28/188 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGT--LSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R GA+ G G PG G L GL + H G + P PGE D
Sbjct: 451 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK---GHRGDTGAQGLPGPPGEDGERGD 507
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P R K G GP + GP G G
Sbjct: 508 DGEIGPRGLPGESGP-------------RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 554
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P G PGPPG QG PG G+PG G G PG PG PG GPPG G G
Sbjct: 555 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG--- 611
Query: 240 KAGTRENQ 247
GT+ NQ
Sbjct: 612 PPGTKGNQ 619
Score = 71.2 bits (173), Expect = 1e-12
Identities = 73/253 (28%), Positives = 92/253 (36%), Gaps = 22/253 (8%)
Query: 13 PAAAPRERGSQG-CGCGGAPARAGEGNSCLLFLGFFG--------LSLALHLLTLCCYLE 63
P P ERG G G G+ G + L+ FG + A +
Sbjct: 335 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 394
Query: 64 LRSELRRERGA---ESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
R LR G R G G PG+ G G L P P P+ PG+
Sbjct: 395 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP-------RGPQGLTGPPGK 447
Query: 121 AALHSDS-QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADGPVKNKKKGKK 178
A + DG + + ++ + + R + +G GP +
Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507
Query: 179 AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPPGPQGPPGLQGPSGA 237
G GP G PG GP G GP G PGIPG PG M GP GP G GPQG PG G G
Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567
Query: 238 ADKAGTRENQPAV 250
G Q A+
Sbjct: 568 PGTQGLPGPQGAI 580
Score = 68.6 bits (166), Expect = 9e-12
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 45/197 (22%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G++ G G G GT + G P P LG P P+ G L GH+
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP----LGYPGPRGVKGVDGIRGLK-----GHK 649
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
FP K + + R + G DGP GP G GP G PG
Sbjct: 650 GEKGEDGFPGFK--GDIGVKGDRGEVGVPGSRGEDGP---------EGPKGRTGPTGDPG 698
Query: 193 PP---GPQGPPGIPGIPGIPGTT----------------------VMGPPGPPGPPGPQG 227
PP G +G G+PG+PG PG + G GP G GP G
Sbjct: 699 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 758
Query: 228 PPGLQGPSGAADKAGTR 244
P G +GP GA K+G +
Sbjct: 759 PRGQRGPRGATGKSGAK 775
Score = 66.2 bits (160), Expect = 5e-11
Identities = 64/212 (30%), Positives = 76/212 (35%), Gaps = 83/212 (39%)
Query: 105 HLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE 164
H Q SP+QQP + LH Q + P EE + + E
Sbjct: 242 HRAQRSPQQQP-----SRLHRPQNQEPQ---------SQDPTPGEEEEILESSLLPPLEE 287
Query: 165 GADGPVKNK-KKGKKA---------GPPGPNGP------------PGPPGPPGPQGPPGI 202
A GP K +KG+ A GPPGP GP PGP G PG +GPPG
Sbjct: 288 AAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGR 347
Query: 203 PGIPGI------PGTTVM-----------------------------------GPPGP-- 219
G+PG PGT++M GPPGP
Sbjct: 348 AGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMG 407
Query: 220 ----PGPPGPQGPPGLQGPSGAADKAGTRENQ 247
PGP G G PGL+G SG G R Q
Sbjct: 408 YTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQ 439
Score = 51.6 bits (122), Expect = 1e-06
Identities = 55/184 (29%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 82 GTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLE---PGEAALH-SDSQDGHQ--M 133
G PG G +G G+ G P P P E PG A L SD G
Sbjct: 313 GPPGPEGPAGLIGPPGIQ---------GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 363
Query: 134 ALLNFFFP----DEKPY--SEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+L F F D+ P ++E + + + G GP+ + G PG G
Sbjct: 364 LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL 423
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
G G GPQGP G G+ G PG G G PG PG +G G G G +
Sbjct: 424 KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 483
Query: 241 AGTR 244
G R
Sbjct: 484 KGHR 487
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/181 (34%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSDSQ 128
+RG G +G PG G + G P+ H G P P + PG A
Sbjct: 801 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 860
Query: 129 D-------GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
D G FP E+ K NEG GP + G
Sbjct: 861 DPGPPGAPGKDGPAGLRGFPGERGLPGTAG-----GPGLKGNEGPSGPPGPAGSPGERGA 915
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
G GP GPPG PGPQGPPG G G+PG GP GP G G QGP GL GP+G A
Sbjct: 916 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGE--KGPIGPTGRDGVQGPVGLPGPAGPPGVA 973
Query: 242 G 242
G
Sbjct: 974 G 974
Score = 85.5 bits (210), Expect = 8e-17
Identities = 67/202 (33%), Positives = 82/202 (40%), Gaps = 37/202 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + R G +G PG G + G L + + G+ PK PG S +
Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPGRQGPKGSLGFPG---FPGASGEKGA 720
Query: 133 MALLNFFFPDEK-----PYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
L P + P + R +K G DGP + G++ G PGP GP
Sbjct: 721 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP--HGPPGER-GLPGPQGP 777
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPP------------------GP 222
G PGP GP GPPG G+PG PG GPPGPP G
Sbjct: 778 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837
Query: 223 PGPQGPPGLQGPSGAADKAGTR 244
PGP GPPG QG G A K GT+
Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTK 859
Score = 85.1 bits (209), Expect = 1e-16
Identities = 60/174 (34%), Positives = 70/174 (40%), Gaps = 19/174 (10%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + +G G GT G G P PI +GQP EPG + G
Sbjct: 975 EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPG-----ARGPQG 1028
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
H A +E +R +G GP K + GP GP GPPGP
Sbjct: 1029 HFGA-----------KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP GP G G G PG G +GPPG G PG G PG+QG G G R
Sbjct: 1078 RGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1129
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/190 (34%), Positives = 79/190 (41%), Gaps = 15/190 (7%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+E R GG G G G + + G P P G+P P PG S Q G
Sbjct: 1220 GSEGRQGGKGAKGDPGAIGAPGKTGPVGP-AGPAGKPGPDGLRGLPG-----SVGQQGRP 1273
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
A P P +R + +K +G G + GPPG G G G
Sbjct: 1274 GATGQAGPPG--PVGPPGLPGLRGDAGAKGEKGHPGLIG------LIGPPGEQGEKGDRG 1325
Query: 193 PPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PGPQG PG G GIPG + +GP GPPG PGP GP G +G +G G + Q
Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385
Query: 252 HLQGQGSAIQ 261
H G IQ
Sbjct: 1386 HPGPPGEVIQ 1395
Score = 82.0 bits (201), Expect = 8e-16
Identities = 77/245 (31%), Positives = 91/245 (37%), Gaps = 18/245 (7%)
Query: 13 PAAAPRERGSQGC-GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRE 71
P E+G G G G P R G S L F GF G S L R E R
Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKGS-LGFPGFPGASGEKGARGLSGKSGPRGE-RGP 735
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH--------LGQPSPKQQPLEPGEAAL 123
G + G G G SG + GG P P G P PK P PG+ L
Sbjct: 736 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 795
Query: 124 HSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
++ P P + + + + G GP + AG
Sbjct: 796 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 855
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPG---IPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
G G PGPPG PG GP G+ G PG +PGT G PG G GP GPPG G G
Sbjct: 856 EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA--GGPGLKGNEGPSGPPGPAGSPGER 913
Query: 239 DKAGT 243
AG+
Sbjct: 914 GAAGS 918
Score = 79.7 bits (195), Expect = 4e-15
Identities = 61/183 (33%), Positives = 74/183 (40%), Gaps = 26/183 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G +G G PG SG G + P P G P P+ P P A D G
Sbjct: 1043 GPPGPIGLQGLPGPSGEKGETGDVGPMGPP----GPPGPRG-PAGPNGA----DGPQGPP 1093
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ N P EK E + + G GP + + ++G PG GPPGP G
Sbjct: 1094 GGVGNLGPPGEKGEPGESG-----SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1148
Query: 193 PPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG-------TRE 245
P G GP G PG G P G PGPPG GP+G G +G G + G T E
Sbjct: 1149 PTGDDGPKGNPGPVGFP-----GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1203
Query: 246 NQP 248
N P
Sbjct: 1204 NGP 1206
Score = 79.3 bits (194), Expect = 5e-15
Identities = 65/202 (32%), Positives = 82/202 (40%), Gaps = 32/202 (15%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSP---------------KQ 113
R E+G + G G PG G G P+ G P P +
Sbjct: 1129 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV-GFPGDPGPPGEGGPRGQDGAKGDRG 1187
Query: 114 QPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK 173
+ EPG+ + + L P P SE + K +K + GA G
Sbjct: 1188 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR----QGGKGAKGDPGAIGAPG-- 1241
Query: 174 KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
K GP GP GP G PGP G +G PG G G PG T G GPPGP GP G PGL+G
Sbjct: 1242 ----KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPVGPPGLPGLRG 1295
Query: 234 PSGAADKAGTRENQPAVVHLQG 255
+GA + G P ++ L G
Sbjct: 1296 DAGAKGEKG----HPGLIGLIG 1313
Score = 77.8 bits (190), Expect = 2e-14
Identities = 58/172 (33%), Positives = 65/172 (37%), Gaps = 46/172 (26%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG + +G G PG SG LG PK P PG + DG
Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLG----------------PKGPPGIPGPPGVRG--MDG 524
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
Q K S +G GP + G PGP G GP
Sbjct: 525 PQGP-----------------------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 561
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G GPQG PG+PG+PG GPPG PG GP G G QGPSG G
Sbjct: 562 HGEKGPQGKPGLPGMPGSD-----GPPGHPGKEGPPGTKGNQGPSGPQGPLG 608
Score = 77.0 bits (188), Expect = 3e-14
Identities = 66/214 (30%), Positives = 79/214 (36%), Gaps = 53/214 (24%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----- 127
G + G SG PG +G+ G PI G+P P+ P GE + +
Sbjct: 893 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP-GRPGPQGPPGAAGEKGVPGEKGPIGP 951
Query: 128 --QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+DG Q + P P V K G G K + GPPGP
Sbjct: 952 TGRDGVQ-GPVGLPGPAGPP-------GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003
Query: 186 GPPGP------------PGPPGPQ---------------GPPGIPGIPGIPGTT------ 212
GP GP PG GPQ GPPG G+ G+PG +
Sbjct: 1004 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063
Query: 213 ----VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
MGPPGPPGP GP GP G GP G G
Sbjct: 1064 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1097
Score = 73.9 bits (180), Expect = 2e-13
Identities = 61/188 (32%), Positives = 68/188 (36%), Gaps = 28/188 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGT--LSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R GA+ G G PG G L GL + H G + P PGE D
Sbjct: 430 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK---GHRGDTGAQGLPGPPGEDGERGD 486
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P R K G GP + GP G G
Sbjct: 487 DGEIGPRGLPGESGP-------------RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 533
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P G PGPPG QG PG G+PG G G PG PG PG GPPG G G
Sbjct: 534 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG--- 590
Query: 240 KAGTRENQ 247
GT+ NQ
Sbjct: 591 PPGTKGNQ 598
Score = 71.2 bits (173), Expect = 1e-12
Identities = 73/253 (28%), Positives = 92/253 (36%), Gaps = 22/253 (8%)
Query: 13 PAAAPRERGSQG-CGCGGAPARAGEGNSCLLFLGFFG--------LSLALHLLTLCCYLE 63
P P ERG G G G+ G + L+ FG + A +
Sbjct: 314 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 373
Query: 64 LRSELRRERGA---ESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
R LR G R G G PG+ G G L P P P+ PG+
Sbjct: 374 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP-------RGPQGLTGPPGK 426
Query: 121 AALHSDS-QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADGPVKNKKKGKK 178
A + DG + + ++ + + R + +G GP +
Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486
Query: 179 AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPPGPQGPPGLQGPSGA 237
G GP G PG GP G GP G PGIPG PG M GP GP G GPQG PG G G
Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
Query: 238 ADKAGTRENQPAV 250
G Q A+
Sbjct: 547 PGTQGLPGPQGAI 559
Score = 68.6 bits (166), Expect = 9e-12
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 45/197 (22%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G++ G G G GT + G P P LG P P+ G L GH+
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP----LGYPGPRGVKGVDGIRGLK-----GHK 628
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
FP K + + R + G DGP GP G GP G PG
Sbjct: 629 GEKGEDGFPGFK--GDIGVKGDRGEVGVPGSRGEDGP---------EGPKGRTGPTGDPG 677
Query: 193 PP---GPQGPPGIPGIPGIPGTT----------------------VMGPPGPPGPPGPQG 227
PP G +G G+PG+PG PG + G GP G GP G
Sbjct: 678 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 737
Query: 228 PPGLQGPSGAADKAGTR 244
P G +GP GA K+G +
Sbjct: 738 PRGQRGPRGATGKSGAK 754
Score = 63.2 bits (152), Expect = 4e-10
Identities = 53/169 (31%), Positives = 65/169 (38%), Gaps = 69/169 (40%)
Query: 148 EEESRRVRRNKRSKSNEGADGPVKNK-KKGKKA---------GPPGPNGP---------- 187
++ SR R + ++ A GP K +KG+ A GPPGP GP
Sbjct: 250 QQPSRLHRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQ 309
Query: 188 --PGPPGPPGPQGPPGIPGIPGI------PGTTVM------------------------- 214
PGP G PG +GPPG G+PG PGT++M
Sbjct: 310 GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQA 369
Query: 215 ----------GPPGP------PGPPGPQGPPGLQGPSGAADKAGTRENQ 247
GPPGP PGP G G PGL+G SG G R Q
Sbjct: 370 ILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQ 418
Score = 51.6 bits (122), Expect = 1e-06
Identities = 55/184 (29%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 82 GTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLE---PGEAALH-SDSQDGHQ--M 133
G PG G +G G+ G P P P E PG A L SD G
Sbjct: 292 GPPGPEGPAGLIGPPGIQ---------GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 342
Query: 134 ALLNFFFP----DEKPY--SEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+L F F D+ P ++E + + + G GP+ + G PG G
Sbjct: 343 LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL 402
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
G G GPQGP G G+ G PG G G PG PG +G G G G +
Sbjct: 403 KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 462
Query: 241 AGTR 244
G R
Sbjct: 463 KGHR 466
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 88.6 bits (218), Expect = 9e-18
Identities = 63/181 (34%), Positives = 72/181 (39%), Gaps = 16/181 (8%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSDSQ 128
+RG G +G PG G + G P+ H G P P + PG A
Sbjct: 908 QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 967
Query: 129 D-------GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
D G FP E+ K NEG GP + G
Sbjct: 968 DPGPPGAPGKDGPAGLRGFPGERGLPGTAG-----GPGLKGNEGPSGPPGPAGSPGERGA 1022
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKA 241
G GP GPPG PGPQGPPG G G+PG GP GP G G QGP GL GP+G A
Sbjct: 1023 AGSGGPIGPPGRPGPQGPPGAAGEKGVPGE--KGPIGPTGRDGVQGPVGLPGPAGPPGVA 1080
Query: 242 G 242
G
Sbjct: 1081 G 1081
Score = 85.5 bits (210), Expect = 8e-17
Identities = 67/202 (33%), Positives = 82/202 (40%), Gaps = 37/202 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + R G +G PG G + G L + + G+ PK PG S +
Sbjct: 772 GPKGRTGPTGDPGPPGLMGEKGKLGVPG-LPGYPGRQGPKGSLGFPG---FPGASGEKGA 827
Query: 133 MALLNFFFPDEK-----PYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
L P + P + R +K G DGP + G++ G PGP GP
Sbjct: 828 RGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP--HGPPGER-GLPGPQGP 884
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPP------------------GP 222
G PGP GP GPPG G+PG PG GPPGPP G
Sbjct: 885 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944
Query: 223 PGPQGPPGLQGPSGAADKAGTR 244
PGP GPPG QG G A K GT+
Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTK 966
Score = 85.1 bits (209), Expect = 1e-16
Identities = 60/174 (34%), Positives = 70/174 (40%), Gaps = 19/174 (10%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + +G G GT G G P PI +GQP EPG + G
Sbjct: 1082 EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-GPVGQPGAAGADGEPG-----ARGPQG 1135
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
H A +E +R +G GP K + GP GP GPPGP
Sbjct: 1136 HFGA-----------KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP GP G G G PG G +GPPG G PG G PG+QG G G R
Sbjct: 1185 RGPAGPNGADGPQGPPG--GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1236
Score = 84.0 bits (206), Expect = 2e-16
Identities = 65/190 (34%), Positives = 79/190 (41%), Gaps = 15/190 (7%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+E R GG G G G + + G P P G+P P PG S Q G
Sbjct: 1327 GSEGRQGGKGAKGDPGAIGAPGKTGPVGP-AGPAGKPGPDGLRGLPG-----SVGQQGRP 1380
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
A P P +R + +K +G G + GPPG G G G
Sbjct: 1381 GATGQAGPPG--PVGPPGLPGLRGDAGAKGEKGHPGLIG------LIGPPGEQGEKGDRG 1432
Query: 193 PPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVV 251
PGPQG PG G GIPG + +GP GPPG PGP GP G +G +G G + Q
Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1492
Query: 252 HLQGQGSAIQ 261
H G IQ
Sbjct: 1493 HPGPPGEVIQ 1502
Score = 82.0 bits (201), Expect = 8e-16
Identities = 77/245 (31%), Positives = 91/245 (37%), Gaps = 18/245 (7%)
Query: 13 PAAAPRERGSQGC-GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRE 71
P E+G G G G P R G S L F GF G S L R E R
Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKGS-LGFPGFPGASGEKGARGLSGKSGPRGE-RGP 842
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH--------LGQPSPKQQPLEPGEAAL 123
G + G G G SG + GG P P G P PK P PG+ L
Sbjct: 843 TGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGL 902
Query: 124 HSDSQDGHQMALLNFFFPDEKP--YSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
++ P P + + + + G GP + AG
Sbjct: 903 PGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGK 962
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPG---IPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
G G PGPPG PG GP G+ G PG +PGT G PG G GP GPPG G G
Sbjct: 963 EGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTA--GGPGLKGNEGPSGPPGPAGSPGER 1020
Query: 239 DKAGT 243
AG+
Sbjct: 1021 GAAGS 1025
Score = 79.7 bits (195), Expect = 4e-15
Identities = 61/183 (33%), Positives = 74/183 (40%), Gaps = 26/183 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G +G G PG SG G + P P G P P+ P P A D G
Sbjct: 1150 GPPGPIGLQGLPGPSGEKGETGDVGPMGPP----GPPGPRG-PAGPNGA----DGPQGPP 1200
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ N P EK E + + G GP + + ++G PG GPPGP G
Sbjct: 1201 GGVGNLGPPGEKGEPGESG-----SPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKG 1255
Query: 193 PPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG-------TRE 245
P G GP G PG G P G PGPPG GP+G G +G G + G T E
Sbjct: 1256 PTGDDGPKGNPGPVGFP-----GDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGE 1310
Query: 246 NQP 248
N P
Sbjct: 1311 NGP 1313
Score = 79.3 bits (194), Expect = 5e-15
Identities = 65/202 (32%), Positives = 82/202 (40%), Gaps = 32/202 (15%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSP---------------KQ 113
R E+G + G G PG G G P+ G P P +
Sbjct: 1236 RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPV-GFPGDPGPPGEGGPRGQDGAKGDRG 1294
Query: 114 QPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK 173
+ EPG+ + + L P P SE + K +K + GA G
Sbjct: 1295 EDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGR----QGGKGAKGDPGAIGAPG-- 1348
Query: 174 KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQG 233
K GP GP GP G PGP G +G PG G G PG T G GPPGP GP G PGL+G
Sbjct: 1349 ----KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT--GQAGPPGPVGPPGLPGLRG 1402
Query: 234 PSGAADKAGTRENQPAVVHLQG 255
+GA + G P ++ L G
Sbjct: 1403 DAGAKGEKG----HPGLIGLIG 1420
Score = 77.8 bits (190), Expect = 2e-14
Identities = 58/172 (33%), Positives = 65/172 (37%), Gaps = 46/172 (26%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
ERG + +G G PG SG LG PK P PG + DG
Sbjct: 590 ERGDDGEIGPRGLPGESGPRGLLG----------------PKGPPGIPGPPGVRG--MDG 631
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
Q K S +G GP + G PGP G GP
Sbjct: 632 PQGP-----------------------KGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGP 668
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G GPQG PG+PG+PG GPPG PG GP G G QGPSG G
Sbjct: 669 HGEKGPQGKPGLPGMPGSD-----GPPGHPGKEGPPGTKGNQGPSGPQGPLG 715
Score = 77.0 bits (188), Expect = 3e-14
Identities = 66/214 (30%), Positives = 79/214 (36%), Gaps = 53/214 (24%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----- 127
G + G SG PG +G+ G PI G+P P+ P GE + +
Sbjct: 1000 GLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPP-GRPGPQGPPGAAGEKGVPGEKGPIGP 1058
Query: 128 --QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+DG Q + P P V K G G K + GPPGP
Sbjct: 1059 TGRDGVQ-GPVGLPGPAGPP-------GVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1110
Query: 186 GPPGP------------PGPPGPQ---------------GPPGIPGIPGIPGTT------ 212
GP GP PG GPQ GPPG G+ G+PG +
Sbjct: 1111 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1170
Query: 213 ----VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
MGPPGPPGP GP GP G GP G G
Sbjct: 1171 GDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVG 1204
Score = 73.9 bits (180), Expect = 2e-13
Identities = 61/188 (32%), Positives = 68/188 (36%), Gaps = 28/188 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGT--LSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R GA+ G G PG G L GL + H G + P PGE D
Sbjct: 537 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEK---GHRGDTGAQGLPGPPGEDGERGD 593
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P R K G GP + GP G G
Sbjct: 594 DGEIGPRGLPGESGP-------------RGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG 640
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAAD 239
P G PGPPG QG PG G+PG G G PG PG PG GPPG G G
Sbjct: 641 PQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG--- 697
Query: 240 KAGTRENQ 247
GT+ NQ
Sbjct: 698 PPGTKGNQ 705
Score = 71.2 bits (173), Expect = 1e-12
Identities = 73/253 (28%), Positives = 92/253 (36%), Gaps = 22/253 (8%)
Query: 13 PAAAPRERGSQG-CGCGGAPARAGEGNSCLLFLGFFG--------LSLALHLLTLCCYLE 63
P P ERG G G G+ G + L+ FG + A +
Sbjct: 421 PVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ 480
Query: 64 LRSELRRERGA---ESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGE 120
R LR G R G G PG+ G G L P P P+ PG+
Sbjct: 481 ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP-------RGPQGLTGPPGK 533
Query: 121 AALHSDS-QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSN-EGADGPVKNKKKGKK 178
A + DG + + ++ + + R + +G GP +
Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 593
Query: 179 AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPPGPQGPPGLQGPSGA 237
G GP G PG GP G GP G PGIPG PG M GP GP G GPQG PG G G
Sbjct: 594 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 653
Query: 238 ADKAGTRENQPAV 250
G Q A+
Sbjct: 654 PGTQGLPGPQGAI 666
Score = 68.6 bits (166), Expect = 9e-12
Identities = 59/197 (29%), Positives = 74/197 (37%), Gaps = 45/197 (22%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G++ G G G GT + G P P LG P P+ G L GH+
Sbjct: 685 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP----LGYPGPRGVKGVDGIRGLK-----GHK 735
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
FP K + + R + G DGP GP G GP G PG
Sbjct: 736 GEKGEDGFPGFK--GDIGVKGDRGEVGVPGSRGEDGP---------EGPKGRTGPTGDPG 784
Query: 193 PP---GPQGPPGIPGIPGIPGTT----------------------VMGPPGPPGPPGPQG 227
PP G +G G+PG+PG PG + G GP G GP G
Sbjct: 785 PPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTG 844
Query: 228 PPGLQGPSGAADKAGTR 244
P G +GP GA K+G +
Sbjct: 845 PRGQRGPRGATGKSGAK 861
Score = 61.6 bits (148), Expect = 1e-09
Identities = 43/128 (33%), Positives = 50/128 (39%), Gaps = 47/128 (36%)
Query: 167 DGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGI------PGTTVM------ 214
+GP + GPPG G PGP G PG +GPPG G+PG PGT++M
Sbjct: 398 EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 457
Query: 215 -----------------------------GPPGP------PGPPGPQGPPGLQGPSGAAD 239
GPPGP PGP G G PGL+G SG
Sbjct: 458 SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLG 517
Query: 240 KAGTRENQ 247
G R Q
Sbjct: 518 PQGPRGPQ 525
Score = 52.4 bits (124), Expect = 7e-07
Identities = 30/67 (44%), Positives = 33/67 (49%), Gaps = 3/67 (4%)
Query: 195 GPQGPPGIPGIPGI--PGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAVVH 252
GP+G G G P + PG V GPPGP GP G GPPG+QG G G R P
Sbjct: 377 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGER-GPPGRAG 435
Query: 253 LQGQGSA 259
L G A
Sbjct: 436 LPGSDGA 442
Score = 51.6 bits (122), Expect = 1e-06
Identities = 55/184 (29%), Positives = 69/184 (37%), Gaps = 30/184 (16%)
Query: 82 GTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLE---PGEAALH-SDSQDGHQ--M 133
G PG G +G G+ G P P P E PG A L SD G
Sbjct: 399 GPPGPEGPAGLIGPPGIQ---------GNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTS 449
Query: 134 ALLNFFFP----DEKPY--SEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+L F F D+ P ++E + + + G GP+ + G PG G
Sbjct: 450 LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGL 509
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
G G GPQGP G G+ G PG G G PG PG +G G G G +
Sbjct: 510 KGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGE 569
Query: 241 AGTR 244
G R
Sbjct: 570 KGHR 573
>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
Length = 1690
Score = 88.6 bits (218), Expect = 9e-18
Identities = 70/199 (35%), Positives = 82/199 (41%), Gaps = 40/199 (20%)
Query: 79 GGSGTPGTSGTLSSLG-----GLDPDSPITSHLGQPSPKQQPLEPGEAALHS-DSQDGHQ 132
G G PG G +G GL D I G P K PG LH Q G +
Sbjct: 1133 GDHGMPGLRGQPGEMGDPGPRGLQGDPGIP---GPPGIKGPSGSPGLNGLHGLKGQKGTK 1189
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP-- 190
A D P ++ + + G P KKG GPPG +GPPGP
Sbjct: 1190 GAS---GLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPP-GPPGSSGPPGPAG 1245
Query: 191 -----------PGPPGPQGPPG------IPGIPGIPGTTVM--------GPPGPPGPPGP 225
PGPPG QGPPG PG PG+PG+ + G PGPPGPPGP
Sbjct: 1246 ATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGP 1305
Query: 226 QGPPGLQGPSGAADKAGTR 244
GPPG +G G K G +
Sbjct: 1306 PGPPGYKGFPGCDGKDGQK 1324
Score = 80.1 bits (196), Expect = 3e-15
Identities = 61/173 (35%), Positives = 75/173 (43%), Gaps = 25/173 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R + GAE G G PG G + GL D + G P P + GE A+ S
Sbjct: 920 RGKPGAEGCPGAKGEPGEKG----MSGLPGDRGLRGAKGAIGP---PGDEGEMAIISQKG 972
Query: 129 DGHQMALLNFFFPDEK-PYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKAGPPGPNG 186
P E P ++ R +K + +G G P + G G PG G
Sbjct: 973 T-----------PGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021
Query: 187 PPGPPGPPGPQGPPGIP---GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PGPPGPPGP G G+ G PG+PG G PG PGPPG G G +GP G
Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGD--QGEPGSPGPPGFSGIDGARGPKG 1072
Score = 79.0 bits (193), Expect = 7e-15
Identities = 56/160 (35%), Positives = 63/160 (39%), Gaps = 19/160 (11%)
Query: 79 GGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G G PG G G G+ P P G P P PG A +
Sbjct: 1201 GPVGIPGLKGERGDPGSPGISPPGP-RGKKGPPGPPGSSGPPGPAGATGRAPKD------ 1253
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
PD P ++ + + G G V + G PG G PGPPGPPGP
Sbjct: 1254 ---IPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLR-----GEPGDCGLPGPPGPPGP 1305
Query: 197 QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
GPPG G PG G G GP G PGPQGP G GP G
Sbjct: 1306 PGPPGYKGFPGCDGKD--GQKGPVGFPGPQGPHGFPGPPG 1343
Score = 78.6 bits (192), Expect = 9e-15
Identities = 64/180 (35%), Positives = 70/180 (38%), Gaps = 18/180 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G G GTPG G G P H G+P K QP PG +
Sbjct: 984 GFPGERGDKGTPGMQGRRGEPGRYGPPG---FHRGEPGEKGQPGPPGPPGPPGST----- 1035
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNK-KKGKKAGPPGPNGPPGPP 191
L F P + E S +GA GP NK GPPGP G PG P
Sbjct: 1036 -GLRGFIGFPGLPGDQGEPGSPGPPGFS-GIDGARGPKGNKGDPASHFGPPGPKGEPGSP 1093
Query: 192 GPPGPQGPPGIPGIPGIPGTTVM----GPPG---PPGPPGPQGPPGLQGPSGAADKAGTR 244
G PG G G G+PGI G GPPG PPG PG G PGL+G G G R
Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPR 1153
Score = 78.2 bits (191), Expect = 1e-14
Identities = 59/175 (33%), Positives = 70/175 (40%), Gaps = 23/175 (13%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G + G SG PG G G G + + I LG PK + G + G
Sbjct: 768 GPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGV--PGPPG 825
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP---NGP 187
H E + + G+ G K + GPPGP G
Sbjct: 826 HSC--------------ERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGL 871
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
PG PG PG GPPG+PGIPG G G PGPPGP GP+G PG G G K G
Sbjct: 872 PGLPGRPGAHGPPGLPGIPGPFGDD--GLPGPPGPKGPRGLPGFPGFPGERGKPG 924
Score = 77.0 bits (188), Expect = 3e-14
Identities = 64/206 (31%), Positives = 75/206 (36%), Gaps = 32/206 (15%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLE---PGEAALHSDS 127
E+G G G+PG G S G P P G P + QP E PG L D
Sbjct: 1104 EQGLPGIQGPRGSPGRPGPPGSSG--PPGCP--GDHGMPGLRGQPGEMGDPGPRGLQGDP 1159
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG------------PVKNKKK 175
+ + P + K K +GA G P ++
Sbjct: 1160 GIPGPPGI-------KGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGER 1212
Query: 176 GKKAGP----PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVM--GPPGPPGPPGPQGPP 229
G P PGP G GPPGPPG GPPG G G + GPPG GPPGP GP
Sbjct: 1213 GDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPR 1272
Query: 230 GLQGPSGAADKAGTRENQPAVVHLQG 255
G GP G +P L G
Sbjct: 1273 GAPGPPGLPGSVDLLRGEPGDCGLPG 1298
Score = 76.3 bits (186), Expect = 5e-14
Identities = 41/81 (50%), Positives = 46/81 (56%), Gaps = 6/81 (7%)
Query: 165 GADGPVKNK-KKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPP 223
G GP K +G A PGP GPPGPPG PG QG G G+PG GT G PGPP
Sbjct: 478 GGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTK-----GDPGPP 532
Query: 224 GPQGPPGLQGPSGAADKAGTR 244
G +GPPGL G GA+ G +
Sbjct: 533 GAEGPPGLPGKHGASGPPGNK 553
Score = 76.3 bits (186), Expect = 5e-14
Identities = 63/208 (30%), Positives = 80/208 (38%), Gaps = 52/208 (25%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + G SG PG G + S + H G+ P P PG+ H +DGH
Sbjct: 539 GLPGKHGASGPPGNKGAKGDM----VVSRVKGHKGERGPDGPPGFPGQPGSHG--RDGHA 592
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
D P + E + +G GP+ GPPG GP GPPG
Sbjct: 593 GEK-----GDPGPPGDHEDA-------TPGGKGFPGPL---------GPPGKAGPVGPPG 631
Query: 193 -----PPGPQGPPGIPGIPGIPGTTVMGP------------PGPPGPPGPQGPP---GLQ 232
PPG +G PG+PG PG+ G + PG GPPG GPP G
Sbjct: 632 LGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFP 691
Query: 233 GPSGAADKAGT-----RENQPAVVHLQG 255
GP GA +G+ R P + G
Sbjct: 692 GPQGAPGLSGSDGHKGRPGTPGTAEIPG 719
Score = 73.2 bits (178), Expect = 4e-13
Identities = 62/205 (30%), Positives = 74/205 (36%), Gaps = 37/205 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + G G PG SG + G SH G P PK +P PG S +
Sbjct: 1048 GDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGL 1107
Query: 133 MALLNFFFPDEKPYSEEESR-------RVRRNKRSKSNEGAD-GPVKNKKKGKKAGPPGP 184
+ +P S R + E D GP + GPPG
Sbjct: 1108 PGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGI 1167
Query: 185 NGPPGPPG-----------------------PPGPQGPPGIPGIPGIPGTTVMGPPGP-- 219
GP G PG PPGP G PG+ G G PG+ + PPGP
Sbjct: 1168 KGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRG 1227
Query: 220 ----PGPPGPQGPPGLQGPSGAADK 240
PGPPG GPPG G +G A K
Sbjct: 1228 KKGPPGPPGSSGPPGPAGATGRAPK 1252
Score = 72.8 bits (177), Expect = 5e-13
Identities = 69/229 (30%), Positives = 80/229 (34%), Gaps = 52/229 (22%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH-------LGQPSPKQQPLEPGEAAL 123
ERG + G G PG+ G G P H G P P P + G
Sbjct: 570 ERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGP 629
Query: 124 HSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
G P E+ + R + D N + GPPG
Sbjct: 630 PGLGFPGP---------PGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPG 680
Query: 184 PNGPPGPPGPPGPQGPPGIPGI------PGIPGTT-VMGPPG-----------------P 219
+GPPGP G PGPQG PG+ G PG PGT + GPPG P
Sbjct: 681 FDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSP 740
Query: 220 PGPPGPQGPPGLQGPSGAADKAGTRENQPAVVHLQGQGSAIQVKNDLSG 268
GPPGP G PG+ G G PA HL G K LSG
Sbjct: 741 VGPPGPPGSPGVNGQKGI-------PGDPAFGHLGPPG-----KRGLSG 777
Score = 71.6 bits (174), Expect = 1e-12
Identities = 64/197 (32%), Positives = 80/197 (40%), Gaps = 39/197 (19%)
Query: 73 GAESRLGGSGTPGTS---------GTLSS--LGGLDPDSPITSHLGQPSPKQQPLEPGEA 121
G++ G GTPGT+ G + GG SP+ G P P P G+
Sbjct: 701 GSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV----GPPGPPGSPGVNGQK 756
Query: 122 ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVK-------NKK 174
+ D GH P ++ S ++ + GA+GP
Sbjct: 757 GIPGDPAFGHLGP------PGKRGLSGVPG--IKGPRGDPGCPGAEGPAGIPGFLGLKGP 808
Query: 175 KGKK--AGPPGPNGPPG------PPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPPGP 225
KG++ AG PG GPPG PG PG G PG PG PG PG G GPPGP G
Sbjct: 809 KGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGM 868
Query: 226 QGPPGLQGPSGAADKAG 242
+G PGL G GA G
Sbjct: 869 KGLPGLPGRPGAHGPPG 885
Score = 71.2 bits (173), Expect = 1e-12
Identities = 60/180 (33%), Positives = 70/180 (38%), Gaps = 30/180 (16%)
Query: 78 LGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
+G G PG G S G L + + G P P PG H S
Sbjct: 499 MGPPGPPGLPGRQGSKGDLGLPGWLGTK-GDPGPPGAEGPPGLPGKHGASGP-------- 549
Query: 138 FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV----------KNKKKGKKAGPPGPNGP 187
P K + V R K K G DGP ++ G+K G PGP G
Sbjct: 550 ---PGNK--GAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEK-GDPGPPGD 603
Query: 188 -----PGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
PG G PGP GPPG G G PG GPPG G PG G PG++GP G + G
Sbjct: 604 HEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKG 663
Score = 70.5 bits (171), Expect = 2e-12
Identities = 54/167 (32%), Positives = 64/167 (38%), Gaps = 8/167 (4%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
+R +RG G G G +G + GLD I H G P P+ +P G D
Sbjct: 93 MRGDRGPPGAAGDKGDKGPTG-VPGFPGLDG---IPGHPGPPGPRGKPGMSGHNGSRGDP 148
Query: 128 QDGHQMALLN----FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPG 183
L P EK + K + + G G GP G
Sbjct: 149 GFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAG 208
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPG 230
P G PG PG GP G PG PG+ G PG V G G PG G QG PG
Sbjct: 209 PTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPG 255
Score = 68.6 bits (166), Expect = 9e-12
Identities = 35/76 (46%), Positives = 44/76 (57%), Gaps = 5/76 (6%)
Query: 178 KAGPPG-PNGPPGPPGPPGPQGPPGIPGIPGIPGTTV----MGPPGPPGPPGPQGPPGLQ 232
+AG PG P+ PG PG PG G PG PG+ G+PG++V +G PGP G G GPPG +
Sbjct: 421 EAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGR 480
Query: 233 GPSGAADKAGTRENQP 248
GP G G +P
Sbjct: 481 GPKGEKGNEGLCACEP 496
Score = 68.2 bits (165), Expect = 1e-11
Identities = 40/93 (43%), Positives = 49/93 (52%), Gaps = 27/93 (29%)
Query: 174 KKGKKAGPPGPNGPPGPPGP---PGP------------QGPPGI---------PGIPGIP 209
+KG + GPPGP GP GP GP PGP +GPPG G+PG P
Sbjct: 60 EKGSR-GPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP 118
Query: 210 GTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G + G PG PGPPGP+G PG+ G +G+ G
Sbjct: 119 G--LDGIPGHPGPPGPRGKPGMSGHNGSRGDPG 149
Score = 67.0 bits (162), Expect = 3e-11
Identities = 74/253 (29%), Positives = 89/253 (35%), Gaps = 49/253 (19%)
Query: 17 PRERGSQGCGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSELRRERGAES 76
P +G+ G G G GE G G +L + C Y + E+G +
Sbjct: 228 PGLKGNPGVGVKGQMGDPGEVGQ----QGSPGPTLLVEPPDFCLY-------KGEKGIKG 276
Query: 77 RLGGSGTPGTSGTLSSLG-GLDPDSPITSHLGQPSPKQQPLE---PGEAALHSDSQDGHQ 132
G G PG G G G + I G P P+ P PG L +
Sbjct: 277 IPGMVGLPGPPGRKGESGIGAKGEKGIP---GFPGPRGDPGSYGSPGFPGLKGELGLVGD 333
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP-NGPPGPP 191
L P P N G GP G PP P GPPG P
Sbjct: 334 PGLFGLIGPKGDP----------------GNRGHPGP-----PGVLVTPPLPLKGPPGDP 372
Query: 192 GPPG---------PQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG P GPPG+ G PG ++GPPGP G PG G PG G G D A
Sbjct: 373 GFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAP 432
Query: 243 TRENQPAVVHLQG 255
+ +P L G
Sbjct: 433 GKPGKPGSPGLPG 445
Score = 65.5 bits (158), Expect = 8e-11
Identities = 55/167 (32%), Positives = 65/167 (38%), Gaps = 8/167 (4%)
Query: 78 LGGSGTPGTSGTLSSLGGLDPDSPITSH---LGQPSPKQQPLEPGEAALHSDSQDGHQMA 134
+G G G G + GG P + +P P P PG D
Sbjct: 462 VGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPG 521
Query: 135 LLNFFFPDEKPYSEEESRRVRRNKRS--KSNEGADGP-VKNKKKGKKA--GPPGPNGPPG 189
L P +E ++ S N+GA G V ++ KG K GP GP G PG
Sbjct: 522 WLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPG 581
Query: 190 PPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSG 236
PG G G G G PG PG PG G PGP GPPG GP G
Sbjct: 582 QPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVG 628
Score = 62.4 bits (150), Expect = 7e-10
Identities = 59/192 (30%), Positives = 70/192 (36%), Gaps = 46/192 (23%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHS-DSQDGH 131
G + G G PG G++ L G D + G P P P PG D +DG
Sbjct: 1267 GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLP---GPPGPPGPPGPPGYKGFPGCDGKDG- 1322
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
Q + F P + G GP K GPPG GP G P
Sbjct: 1323 QKGPVGFPGP-------------------QGPHGFPGPPGEKGL---PGPPGRKGPTGLP 1360
Query: 192 GPPGPQGPPG-------IPGIPGIPGTT----VMGPPGPPGP--------PGPQGPPGLQ 232
GP G GPP IPG+PG PG MG PG GP PG G G+
Sbjct: 1361 GPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVD 1420
Query: 233 GPSGAADKAGTR 244
G G+ G +
Sbjct: 1421 GVPGSPGPPGRK 1432
Score = 62.0 bits (149), Expect = 9e-10
Identities = 35/73 (47%), Positives = 38/73 (52%), Gaps = 15/73 (20%)
Query: 180 GPPGPNG--------------PPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGP 225
GPPGP G PPGP G PG G PG GIPG P + G PG PG PG
Sbjct: 385 GPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRP-DSAPGKPGKPGSPGL 443
Query: 226 QGPPGLQGPSGAA 238
G PGLQG G++
Sbjct: 444 PGAPGLQGLPGSS 456
Score = 60.1 bits (144), Expect = 3e-09
Identities = 52/173 (30%), Positives = 69/173 (39%), Gaps = 25/173 (14%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHL-GQPSPKQQPLEPGEAALHSDSQDGHQMALLN 137
G G PG SG+ G P +P T+ + G P + +PG S G
Sbjct: 692 GPQGAPGLSGSDGHKGR--PGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVG------- 742
Query: 138 FFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQ 197
P P S + ++ + A G + K +G PG GP G PG PG +
Sbjct: 743 ---PPGPPGSPGVN-----GQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAE 794
Query: 198 GPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
GP GIPG G+ G G PGPPG +G PG+ G G G+
Sbjct: 795 GPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 847
Score = 55.8 bits (133), Expect = 6e-08
Identities = 34/72 (47%), Positives = 38/72 (52%), Gaps = 8/72 (11%)
Query: 165 GADGPVKNKKKGKKA--GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP 222
G GP KG+ G G +G PG PGPPG +G G G PG P GPPGP G
Sbjct: 1398 GMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGP-----GPPGPIGD 1452
Query: 223 PGPQG-PPGLQG 233
PGP+G PG G
Sbjct: 1453 PGPKGFGPGYLG 1464
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/85 (40%), Positives = 40/85 (47%), Gaps = 8/85 (9%)
Query: 158 KRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPP 217
K + + G G +K G PG G G PG PGP GP G PG+ G G+ G P
Sbjct: 91 KGMRGDRGPPGAAGDKGDKGPTGVPGFPGLDGIPGHPGPPGPRGKPGMSGHNGS--RGDP 148
Query: 218 GPP------GPPGPQGPPGLQGPSG 236
G P GP GP G PG +G G
Sbjct: 149 GFPGGRGALGPGGPLGHPGEKGEKG 173
Score = 52.0 bits (123), Expect = 9e-07
Identities = 37/108 (34%), Positives = 42/108 (38%), Gaps = 43/108 (39%)
Query: 180 GPPGPNGPPG---------PPGPPG------PQGP------------------------- 199
GPPGP G PG PG PG P GP
Sbjct: 128 GPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFILGAVKGIQG 187
Query: 200 -PGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTREN 246
G PG+PG+PG+ G GP GP G G PGL GP G + G + N
Sbjct: 188 DRGDPGLPGLPGS--WGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGN 233
Score = 44.7 bits (104), Expect = 1e-04
Identities = 19/37 (51%), Positives = 22/37 (59%)
Query: 208 IPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
+P GPPGPPGP GP GP G GP G + + G R
Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMR 94
Score = 37.0 bits (84), Expect = 0.031
Identities = 21/50 (42%), Positives = 22/50 (44%), Gaps = 14/50 (28%)
Query: 195 GPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G +GPPG PPGP GP GP G PG G SG G R
Sbjct: 62 GSRGPPG--------------PPGPQGPIGPLGAPGPIGLSGEKGMRGDR 97
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 87.8 bits (216), Expect = 2e-17
Identities = 42/67 (62%), Positives = 42/67 (62%), Gaps = 2/67 (2%)
Query: 176 GKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPS 235
G AG PGP GPPGPPGPPG G PG PG PG G G PG GP GP GPPG GPS
Sbjct: 167 GGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP--GEPGQAGPSGPPGPPGAIGPS 224
Query: 236 GAADKAG 242
G A K G
Sbjct: 225 GPAGKDG 231
Score = 84.0 bits (206), Expect = 2e-16
Identities = 71/237 (29%), Positives = 80/237 (33%), Gaps = 78/237 (32%)
Query: 13 PAAAPRERGSQG----CGCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSEL 68
P +P ERG G G GAP + GE
Sbjct: 793 PRGSPGERGETGPPGPAGFPGAPGQNGEPGG----------------------------- 823
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
+ ERGA G G PG +G G P P G + P PG A
Sbjct: 824 KGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGP----QGVKGERGSPGGPGAAG------ 873
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
FP + G GP + GPPGP+G P
Sbjct: 874 -----------FPGAR--------------------GLPGPPGSNGN---PGPPGPSGSP 899
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G GPPGP G G PG PG+ G G PG G PG QGPPG GP G A G R
Sbjct: 900 GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956
Score = 83.2 bits (204), Expect = 4e-16
Identities = 66/185 (35%), Positives = 72/185 (38%), Gaps = 44/185 (23%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R G R G G PG G S GG D G+P P E G S
Sbjct: 518 RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSD-------GKPGPPGSQGESGRPGPPGPSG 570
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP--PGPNG 186
Q ++ F P K N+GA G K G++ GP PGP G
Sbjct: 571 PRGQPGVMGFPGP-------------------KGNDGAPG-----KNGERGGPGGPGPQG 606
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPP---------GPPGPQGPPGLQGPSGA 237
PPG G GPQGPPG G G G T GPPGP GPPG G PG GP G
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDT--GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664
Query: 238 ADKAG 242
A G
Sbjct: 665 AGAPG 669
Score = 80.9 bits (198), Expect = 2e-15
Identities = 60/177 (33%), Positives = 72/177 (40%), Gaps = 20/177 (11%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH----SD 126
++G G G PG G G + P P GQP K + PG + S
Sbjct: 742 DKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA----GQPGDKGEGGAPGLPGIAGPRGSP 797
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ G FP + E + R + EG V AGPPG +G
Sbjct: 798 GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV--------AGPPGGSG 849
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
P GPPGP G +G G PG PG G G PGPPG G GPP GPSG+ K G
Sbjct: 850 PAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPP---GPSGSPGKDG 903
Score = 77.4 bits (189), Expect = 2e-14
Identities = 66/202 (32%), Positives = 78/202 (38%), Gaps = 46/202 (22%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+ G +G PG +G + G P P G+ P + PG A + + +
Sbjct: 468 GSPGEPGANGLPGAAGERGAPGFRGPAGP-NGIPGEKGPAGERGAPGPAGPRGAAGEPGR 526
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
D P +R S G+DG K GPPG G G PG
Sbjct: 527 ---------DGVPGGPG----MRGMPGSPGGPGSDG---------KPGPPGSQGESGRPG 564
Query: 193 PPGPQGPPGIPGIPGIPGTT-------------VMGPPGPPGPP------GPQGPPGLQG 233
PPGP GP G PG+ G PG G PGP GPP GPQGPPG G
Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTG 624
Query: 234 PSGAADKAGTRENQPAVVHLQG 255
P G DK T P LQG
Sbjct: 625 PGG--DKGDT--GPPGPQGLQG 642
Score = 76.6 bits (187), Expect = 3e-14
Identities = 59/179 (32%), Positives = 70/179 (39%), Gaps = 14/179 (7%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSP---KQQPLEPGEAALHS 125
E+G+ G G PG G G GL + G P P K + +PG L
Sbjct: 931 EKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSG 990
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+ L +P + N S G DG K + G PG
Sbjct: 991 ERGPPGPQGLPGLAGTAGEPGRDG-------NPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043
Query: 186 GPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
G PG PGPPGP GP G G G G GP G PGP G +G PG QGP G + G R
Sbjct: 1044 GAPGHPGPPGPVGPAGKSGDRGESGPA--GPAGAPGPAGSRGAPGPQGPRGDKGETGER 1100
Score = 76.6 bits (187), Expect = 3e-14
Identities = 61/190 (32%), Positives = 71/190 (37%), Gaps = 32/190 (16%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R E G+ G G PG G + G G +S G P P PG D
Sbjct: 1034 RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGD 1093
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG---PVKNKKKGKKAGPPG 183
+ E + ++ ++ N GA G P + GP G
Sbjct: 1094 KGET----------------GERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAG 1137
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGPPGLQGPS- 235
P GP GP GPPG G G PG G PG G PG PG PGP GPPG GP
Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCC 1197
Query: 236 ---GAADKAG 242
GAA AG
Sbjct: 1198 GGVGAAAIAG 1207
Score = 76.3 bits (186), Expect = 5e-14
Identities = 63/200 (31%), Positives = 75/200 (37%), Gaps = 50/200 (25%)
Query: 65 RSELRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEA--- 121
R+ + E GA G +G PG +G +G G P + +P PG A
Sbjct: 271 RNGEKGETGAPGLKGENGLPGENGAPGPMGPR----------GAPGERGRPGLPGAAGAR 320
Query: 122 ----ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGK 177
A SD Q G FP + GA G V
Sbjct: 321 GNDGARGSDGQPGPPGPPGTAGFP--------------------GSPGAKGEVGPAGSPG 360
Query: 178 KAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG-------------TTVMGPPGPPGPPG 224
G PG G PGP G G QGPPG PGI G PG +MG GPPGP G
Sbjct: 361 SNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAG 420
Query: 225 PQGPPGLQGPSGAADKAGTR 244
G PGL+G +G K G +
Sbjct: 421 ANGAPGLRGGAGEPGKNGAK 440
Score = 75.9 bits (185), Expect = 6e-14
Identities = 61/182 (33%), Positives = 72/182 (39%), Gaps = 32/182 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+G G G PG +G GG P P G P P G L
Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGP-EGGKGAAGPPGPPGAAGTPGLQG------ 726
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKAGPPGPNGPPGP 190
P E+ S + +K GADG P K+ +G P GP GPPGP
Sbjct: 727 --------MPGER--GGLGSPGPKGDKGEPGGPGADGVPGKDGPRG----PTGPIGPPGP 772
Query: 191 PGPPGPQGPPGIPGIPGIPGTT-------VMGPPGP---PGPPGPQGPPGLQGPSGAADK 240
G PG +G G PG+PGI G GPPGP PG PG G PG +G GA +
Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGE 832
Query: 241 AG 242
G
Sbjct: 833 KG 834
Score = 73.2 bits (178), Expect = 4e-13
Identities = 55/180 (30%), Positives = 65/180 (36%), Gaps = 43/180 (23%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G G PG +G GG P P + G+ P+ P G D+ L
Sbjct: 585 GNDGAPGKNGERGGPGGPGPQGPPGKN-GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGL 643
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP------G 192
G GP K + GP G G PG P G
Sbjct: 644 -------------------------PGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAG 678
Query: 193 PPGPQGPPGIPGIPGIPGTTVMGPP---------GPPGPPGPQGPPGLQGPSGAADKAGT 243
PG +GPPG+ G PG+ G GPP GPPGPPG G PGLQG G G+
Sbjct: 679 APGERGPPGLAGAPGLRGGA--GPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736
Score = 72.8 bits (177), Expect = 5e-13
Identities = 60/191 (31%), Positives = 77/191 (40%), Gaps = 21/191 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPG----EAALHSD 126
GA +G G PG +G + G G + G+P P+ + E G A D
Sbjct: 405 GAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGED 464
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRS-KSNEGADGPVKNKKKGKKAGPPGPN 185
+DG P E + R + G +G K + G PGP
Sbjct: 465 GKDGS---------PGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPA 515
Query: 186 GPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP G G PG G PG PG+ G+PG+ G G PGPPG QG G GP G + G
Sbjct: 516 GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRG-- 573
Query: 245 ENQPAVVHLQG 255
QP V+ G
Sbjct: 574 --QPGVMGFPG 582
Score = 72.0 bits (175), Expect = 9e-13
Identities = 38/96 (39%), Positives = 41/96 (42%), Gaps = 33/96 (34%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT--------------------------- 212
GP GP G PGPPG PG G PGIPG PG PG+
Sbjct: 103 GPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKS 162
Query: 213 ------VMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
+ G PGP GPPGP GPPG G G+ G
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPG 198
Score = 70.5 bits (171), Expect = 2e-12
Identities = 60/198 (30%), Positives = 73/198 (36%), Gaps = 37/198 (18%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSP--ITSHLGQPSPKQQPLEPGEAALHSDSQ 128
ERG G G PG +G G P P G P P+ PG ++
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654
Query: 129 DGHQMALLNFFFPDEK-PYSEEESRRVRRNKRSKSNEGADGP-----VKNKKKGKKAGPP 182
P E P + + K G GP + G AGPP
Sbjct: 655 K-----------PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGG--AGPP 701
Query: 183 GPNGPPGPPGPPGPQGPPGIPGIPGIPGTTV-MGPPGP---------------PGPPGPQ 226
GP G G GPPGP G G PG+ G+PG +G PGP PG GP+
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761
Query: 227 GPPGLQGPSGAADKAGTR 244
GP G GP G A + G +
Sbjct: 762 GPTGPIGPPGPAGQPGDK 779
Score = 69.7 bits (169), Expect = 4e-12
Identities = 60/193 (31%), Positives = 69/193 (35%), Gaps = 69/193 (35%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNF 138
G G PGTSG P SP G P + P EPG+A
Sbjct: 180 GPPGPPGTSG--------HPGSP-----GSPGYQGPPGEPGQAG---------------- 210
Query: 139 FFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQG 198
P P GA GP K ++G PG G G PGPPG +G
Sbjct: 211 --PSGPP----------------GPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKG 252
Query: 199 PPGIPGIPGIPG----------------------TTVMGPPGPPGPPGPQGPPGLQGPSG 236
P GIPG PG+ G + G G PGP GP+G PG +G G
Sbjct: 253 PAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPG 312
Query: 237 AADKAGTRENQPA 249
AG R N A
Sbjct: 313 LPGAAGARGNDGA 325
Score = 65.9 bits (159), Expect = 6e-11
Identities = 66/206 (32%), Positives = 79/206 (38%), Gaps = 41/206 (19%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPS---PKQQPLEPGEAALHSD 126
RG G +G PG G S G P P T G P PK +PGE S
Sbjct: 878 RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG--SP 935
Query: 127 SQDGHQMALLNFFFPDEKPYSE-EESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
G A P + +R + G+ GP K + +G PG N
Sbjct: 936 GAQGPPGA------PGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE---SGKPGAN 986
Query: 186 GPPGPPGPPGPQGPPGI------------PGIPGIPGTT----------VMGPPGPPGPP 223
G G GPPGPQG PG+ PG G+PG G PG PG P
Sbjct: 987 GLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP 1046
Query: 224 GPQGPPGLQGPSGAADKAGTRENQPA 249
G GPPG GP+G + G E+ PA
Sbjct: 1047 GHPGPPGPVGPAGKSGDRG--ESGPA 1070
Score = 63.5 bits (153), Expect = 3e-10
Identities = 55/182 (30%), Positives = 66/182 (36%), Gaps = 10/182 (5%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G + G G PG G+ G D G P P PG S D
Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKG----DRGENGSPGAPGAPGHPGPPGPVGPAGKSGDR 1064
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+ P P SR + + ++G G G PG G PG
Sbjct: 1065 GESGPAG---PAGAP-GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAV 250
PGP G QG G PG G G +GP GPPG G G PG GP G G R ++ +
Sbjct: 1121 PGPAGQQGAIGSPGPAGPRGP--VGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178
Query: 251 VH 252
H
Sbjct: 1179 GH 1180
Score = 61.2 bits (147), Expect = 2e-09
Identities = 29/52 (55%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGL 231
P P P PP GPQGP G PG PGIPG G PG PG PG GPPG+
Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGI 140
Score = 38.1 bits (87), Expect = 0.014
Identities = 22/62 (35%), Positives = 24/62 (38%), Gaps = 17/62 (27%)
Query: 184 PNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP---PGPQGPPGLQGPSGAADK 240
P P P PP QGP GP G PGP PG G PG+ G G+
Sbjct: 89 PQPPTAPTRPPNGQGP--------------QGPKGDPGPPGIPGRNGDPGIPGQPGSPGS 134
Query: 241 AG 242
G
Sbjct: 135 PG 136
>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
Length = 680
Score = 87.8 bits (216), Expect = 2e-17
Identities = 66/188 (35%), Positives = 74/188 (39%), Gaps = 31/188 (16%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSP--ITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
GA+ G +G PG G G + P P I G P PK + G A
Sbjct: 320 GAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAG-------- 371
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+P K E S G DGP N G PG GPPG
Sbjct: 372 ---------YPGAK--GERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGGPPGL 420
Query: 191 PGPPGPQGPPGIPG---------IPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PGP GP G G+PG PGIPGT +GPPG PG PG +G PG GP G A
Sbjct: 421 PGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAGI 480
Query: 241 AGTRENQP 248
A N P
Sbjct: 481 ATKGLNGP 488
Score = 76.3 bits (186), Expect = 5e-14
Identities = 60/175 (34%), Positives = 68/175 (38%), Gaps = 28/175 (16%)
Query: 73 GAESRLGGSGTPGTSGT----LSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
G G SG PG G L GL P P S +G+P P +PGE +
Sbjct: 69 GPRGHPGPSGPPGKPGYGSPGLQGEPGL-PGPPGPSAVGKPGVPGLPGKPGERGPYGPKG 127
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
D L P P G GP GK G GP G P
Sbjct: 128 DVGPAGLPGPRGPPGPP-------------------GIPGPAGISVPGKP-GQQGPTGAP 167
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGP---PGPQGPPGLQGPSGAADK 240
GP G PG +G PG+PG+ G G G PG PG PGPQGP G GP G +
Sbjct: 168 GPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKR 222
Score = 75.5 bits (184), Expect = 8e-14
Identities = 64/195 (32%), Positives = 77/195 (39%), Gaps = 30/195 (15%)
Query: 76 SRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMAL 135
S +G G PG G G P + G P P+ P PG S G
Sbjct: 103 SAVGKPGVPGLPGKPGERGPYGPKGDV-GPAGLPGPRGPPGPPGIPGPAGISVPG----- 156
Query: 136 LNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKA-GPPGPNGPPGPPGP 193
KP ++ + +GA G P N +KG+ G PG G G PGP
Sbjct: 157 --------KP-GQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGP 207
Query: 194 PGPQGPPGIP--------GIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAADK- 240
GP GP G P G+PG PG G GP GPPGPQGPPG +GP G
Sbjct: 208 QGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPG 267
Query: 241 AGTRENQPAVVHLQG 255
A QP + +G
Sbjct: 268 AAGAPGQPGIPGTKG 282
Score = 71.6 bits (174), Expect = 1e-12
Identities = 57/189 (30%), Positives = 71/189 (37%), Gaps = 46/189 (24%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RG G G PG +G +G P P G P P+ G + ++G
Sbjct: 170 RGFPGEKGAPGVPGMNGQKGEMGYGAPGRP--GERGLPGPQGPTGPSGPPGVGKRGENG- 226
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P + K + G GP+ GPPGP GPPG
Sbjct: 227 --------VPGQPGI-----------KGDRGFPGEMGPI---------GPPGPQGPPGER 258
Query: 192 GP-----------PGPQGPPGIPGIPGIPGTTVMGPPGPP--GPPGPQGPPGLQGPSGAA 238
GP PG G PG G+PG PG + GPPGPP G PG G G +GP+G
Sbjct: 259 GPEGIGKPGAAGAPGQPGIPGTKGLPGAPG--IAGPPGPPGFGKPGLPGLKGERGPAGLP 316
Query: 239 DKAGTRENQ 247
G + Q
Sbjct: 317 GGPGAKGEQ 325
Score = 70.5 bits (171), Expect = 2e-12
Identities = 43/111 (38%), Positives = 49/111 (44%), Gaps = 26/111 (23%)
Query: 158 KRSKSNEGADGPVKNKK---------KGKKAGPPGPNGPPGPPGP------PGPQGPP-- 200
+R + G GP+ N K K K G G PGPPGP PGP GPP
Sbjct: 23 ERYQMPTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGK 82
Query: 201 ---------GIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG+PG PG + +G PG PG PG G G GP G AG
Sbjct: 83 PGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAG 133
Score = 69.7 bits (169), Expect = 4e-12
Identities = 41/85 (48%), Positives = 44/85 (51%), Gaps = 12/85 (14%)
Query: 169 PVKNKKKG----KKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPG 224
P K KG + G PGP GP GP G PGP GPPG PG G PG + G PG PGPPG
Sbjct: 45 PYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGY-GSPG--LQGEPGLPGPPG 101
Query: 225 PQ-----GPPGLQGPSGAADKAGTR 244
P G PGL G G G +
Sbjct: 102 PSAVGKPGVPGLPGKPGERGPYGPK 126
Score = 69.7 bits (169), Expect = 4e-12
Identities = 36/77 (46%), Positives = 40/77 (51%), Gaps = 14/77 (18%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGI--------PGIPGIPGTTVMGPPG------PPGPPGP 225
GPPGP GP G PGP GP G PG PG+PG PG + +G PG PG GP
Sbjct: 63 GPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGP 122
Query: 226 QGPPGLQGPSGAADKAG 242
GP G GP+G G
Sbjct: 123 YGPKGDVGPAGLPGPRG 139
Score = 67.8 bits (164), Expect = 2e-11
Identities = 56/182 (30%), Positives = 69/182 (37%), Gaps = 16/182 (8%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSH----LGQPSPKQQPLEPGEAALH 124
R E G + G G G G + +G P P +G+P P +PG
Sbjct: 222 RGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTK 281
Query: 125 SDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGP 184
P P + + +R + G G K + AG PG
Sbjct: 282 G------LPGAPGIAGPPGPPGFGKPGLPGLKGERGPA--GLPGGPGAKGEQGPAGLPGK 333
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPG----TTVMGPPGPPGPPGPQGPPGLQGPSGAADK 240
G GPPG GPQGP GIPG G+PG T GP G PG G +G PG G G K
Sbjct: 334 PGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK 393
Query: 241 AG 242
G
Sbjct: 394 PG 395
Score = 53.1 bits (126), Expect = 4e-07
Identities = 42/138 (30%), Positives = 48/138 (34%), Gaps = 25/138 (18%)
Query: 79 GGSGTPGTSGTLSSLGGLDPDSP--ITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALL 136
G G PG G G + P + H G+ P+ P PG
Sbjct: 407 GPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRG-------------- 452
Query: 137 NFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGP 196
P +K + G GP KG GP GP GPPGP G G
Sbjct: 453 --------PIGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLN-GPTGPPGPPGPRGHSGE 503
Query: 197 QGPPGIPGIPGIPGTTVM 214
G PG PG PG PG VM
Sbjct: 504 PGLPGPPGPPGPPGQAVM 521
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 87.4 bits (215), Expect = 2e-17
Identities = 65/198 (32%), Positives = 76/198 (38%), Gaps = 23/198 (11%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E+G G +G+ G G G P P G P QP GE D
Sbjct: 802 EKGEVGPPGPAGSAGARGAPGERGETGPPGP-AGFAGPPGADGQPGAKGEQGEAGQKGDA 860
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
P P + V K ++ +G G + GPPG NG PGP
Sbjct: 861 GAPGPQG---PSGAP-GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 916
Query: 191 PGPPGP------------QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
PGPPGP GPPG G PG+ G GPPG G PG GP G +GP G
Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGDDGPSGAEGPPGPQ 974
Query: 239 DKAGTRENQPAVVHLQGQ 256
AG R +V L GQ
Sbjct: 975 GLAGQR----GIVGLPGQ 988
Score = 87.4 bits (215), Expect = 2e-17
Identities = 67/205 (32%), Positives = 76/205 (37%), Gaps = 31/205 (15%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G E G G PG G G+ D T +G P P PG A D
Sbjct: 1033 EPGREGSPGADGPPGRDGA----AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088
Query: 131 HQMALLNFFFPD----------------EKPYSEEESRRVRRNKRSKSN----EGADGPV 170
+ P +K + E R + R + G GP
Sbjct: 1089 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1148
Query: 171 KNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG-------TTVMGPPGPPGPP 223
++ AGP GP GPPGP GP G G GIPG G PG T GPPG PGPP
Sbjct: 1149 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208
Query: 224 GPQGPPGLQGPSGAADKAGTRENQP 248
GP GPPG A G RE P
Sbjct: 1209 GPPGPPGPGIDMSAFAGLGPREKGP 1233
Score = 85.1 bits (209), Expect = 1e-16
Identities = 41/65 (63%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
GP GP GPPGP G PGPQG G PG PG PG V GP GP GPPGP G PG G +G
Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG--VSGPMGPRGPPGPPGKPGDDGEAGKPG 261
Query: 240 KAGTR 244
KAG R
Sbjct: 262 KAGER 266
Score = 80.9 bits (198), Expect = 2e-15
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 47/203 (23%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R GA+ G G PGT GT G P P + G P + P E G A +
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-GPPGLQGMPGERGAAGIAGPKG 765
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV-------KNKKKGKKAGP 181
D + P+ P + G GP+ N +KG+ GP
Sbjct: 766 DRGDVGEKG---PEGAPGKD-------------GGRGLTGPIGPPGPAGANGEKGE-VGP 808
Query: 182 PGP------------NGPPGPPGPPGPQGPPGIPGIPGIPG----------TTVMGPPGP 219
PGP G GPPGP G GPPG G PG G GP GP
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 868
Query: 220 PGPPGPQGPPGLQGPSGAADKAG 242
G PGPQGP G+ GP GA G
Sbjct: 869 SGAPGPQGPTGVTGPKGARGAQG 891
Score = 78.2 bits (191), Expect = 1e-14
Identities = 61/198 (30%), Positives = 80/198 (40%), Gaps = 31/198 (15%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSD-SQDGH 131
G + G G PG G +G P P G+P + +PG+A G
Sbjct: 219 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPP----GKPGDDGEAGKPGKAGERGPPGPQGA 274
Query: 132 QMALLNFFFPDEKPY----------SEEESRRVRRNKRSKSNEGADGPVKNK----KKGK 177
+ P K + E + V+ S G+ GP+ + ++G+
Sbjct: 275 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 334
Query: 178 K-----AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG-------TTVMGPPGPPGPPGP 225
AG G +G PGP GPPGP GP G PG PG PG T GP G GP G
Sbjct: 335 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 394
Query: 226 QGPPGLQGPSGAADKAGT 243
G PG GP+GA+ GT
Sbjct: 395 PGTPGSPGPAGASGNPGT 412
Score = 77.4 bits (189), Expect = 2e-14
Identities = 61/178 (34%), Positives = 68/178 (38%), Gaps = 19/178 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G R G +G G G G P P+ G P P GEA G +
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPV-GPAGGPGFPGAPGAKGEAG--PTGARGPE 386
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKA-----GPPGPNG 186
A + P E + + N G DG P G G PGP G
Sbjct: 387 GA--------QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
PPGP G GP GP G G PGI G G GP G PGP GP G GP+G K G R
Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAG--FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494
Score = 77.4 bits (189), Expect = 2e-14
Identities = 75/243 (30%), Positives = 90/243 (37%), Gaps = 53/243 (21%)
Query: 13 PAAAPRERGSQGC----GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSEL 68
P AP ERG G G G P R GE GL A L +
Sbjct: 526 PKGAPGERGPSGLAGPKGANGDPGRPGEP----------GLPGARGL----------TGR 565
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
+ G + ++G SG PG G G +G P PK EPG+A
Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ-PGVMGFPGPKGANGEPGKAG------ 618
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE----GADGPVKNKKKGKKAGPPGP 184
EK R K ++ G GP + + GP G
Sbjct: 619 --------------EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPP---GLQGPSGAADK 240
G PGPPGPPG G PG G+PG G ++GP G G PG +G P GLQGP G
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724
Query: 241 AGT 243
GT
Sbjct: 725 PGT 727
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/201 (31%), Positives = 74/201 (36%), Gaps = 37/201 (18%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RGA+ G +G PG +G + G + G P P + G DS
Sbjct: 887 RGAQGPPGATGFPGAAGRVGPPGS-------NGNPGPPGPPGPSGKDGPKGARGDSGPPG 939
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP- 190
+ P P K G DGP GPPGP G G
Sbjct: 940 RAGEPGLQGPAGPP-------------GEKGEPGDDGP------SGAEGPPGPQGLAGQR 980
Query: 191 -----PGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
PG G +G PG+PG G PG G G GPPGP GPPGL GP+G R
Sbjct: 981 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPG----R 1036
Query: 245 ENQPAVVHLQGQGSAIQVKND 265
E P G+ A VK D
Sbjct: 1037 EGSPGADGPPGRDGAAGVKGD 1057
Score = 74.3 bits (181), Expect = 2e-13
Identities = 44/88 (50%), Positives = 49/88 (55%), Gaps = 11/88 (12%)
Query: 161 KSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGI------PGTTVM 214
K +G G +K+ K GPPGP GP G GP G +G G G PG PGT
Sbjct: 103 KGQKGEPGDIKDIVGPK--GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP-- 158
Query: 215 GPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PGPPGPPGP GPPGL G + AA AG
Sbjct: 159 GNPGPPGPPGPPGPPGL-GGNFAAQMAG 185
Score = 74.3 bits (181), Expect = 2e-13
Identities = 60/205 (29%), Positives = 71/205 (34%), Gaps = 42/205 (20%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
LR G + G +G PG +G G P + G P P P PGE D
Sbjct: 628 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP-SGFQGLPGP---PGPPGEGGKPGDQ 683
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+ P R R + + GA G + G GP G
Sbjct: 684 GVPGEAGAPGLVGP----------RGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 733
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT----------------------------VMGPPGP 219
GP GPPG QGPPG+ G+PG G + GP GP
Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 793
Query: 220 PGPPGPQGPPGLQGPSGAADKAGTR 244
PGP G G G GP G A AG R
Sbjct: 794 PGPAGANGEKGEVGPPGPAGSAGAR 818
Score = 73.2 bits (178), Expect = 4e-13
Identities = 54/161 (33%), Positives = 65/161 (40%), Gaps = 52/161 (32%)
Query: 107 GQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGA 166
GQP PK Q EPG+ + + P P + + G
Sbjct: 98 GQPGPKGQKGEPGD--------------IKDIVGPKGPPGPQGPA-------------GE 130
Query: 167 DGPVKNK-KKGKKA--GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTV---------- 213
GP ++ KG+K GP G +G PG PG PGP GPPG PG PG+ G
Sbjct: 131 QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEK 190
Query: 214 ------------MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
MGP GP GPPGP G PG QG G + G
Sbjct: 191 AGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231
Score = 73.2 bits (178), Expect = 4e-13
Identities = 64/224 (28%), Positives = 79/224 (35%), Gaps = 67/224 (29%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH-----S 125
E+GA G G PGT G +P P G P P P G A
Sbjct: 142 EKGAPGPRGRDGEPGTPG--------NPGPP-----GPPGPPGPPGLGGNFAAQMAGGFD 188
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+ G Q+ ++ + P R + +G G + +GP GP
Sbjct: 189 EKAGGAQLGVM------QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR 242
Query: 186 GPPGPPG------------------PPGPQGPPGIPGIPGIPGTT--------------- 212
GPPGPPG PPGPQG G PG PG+PG
Sbjct: 243 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 302
Query: 213 ----------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTREN 246
G G PGP GP+G PG +G +G A AG R N
Sbjct: 303 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 346
Score = 72.8 bits (177), Expect = 5e-13
Identities = 66/203 (32%), Positives = 77/203 (37%), Gaps = 22/203 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G G +G PG +G G P P G PK Q EPG A + +
Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QGATGPLGPKGQTGEPGIAGFKGEQGPKGE 472
Query: 133 MALLNFFFPDEKPY-SEEESRRVRRNKRS-------KSNEGADG----PVKNKKKGKKAG 180
P P + EE +R R + GA G P ++ G K G
Sbjct: 473 PGPAG---PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK-G 528
Query: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPG----TTVMGPPGPPGPPGPQGPPGLQGPSG 236
PG GP G GP G G PG PG PG+PG T G GP G GP G PG G G
Sbjct: 529 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588
Query: 237 AADKAGTRENQPAVVHLQGQGSA 259
G R QP V+ G A
Sbjct: 589 PPGPQGAR-GQPGVMGFPGPKGA 610
Score = 71.6 bits (174), Expect = 1e-12
Identities = 61/198 (30%), Positives = 67/198 (33%), Gaps = 39/198 (19%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+ G G PG SG G P G+P + PGE D DG
Sbjct: 909 GSNGNPGPPGPPGPSGKDGPKGARGDSGP-PGRAGEPGLQGPAGPPGEKGEPGD--DGPS 965
Query: 133 MALLNFFFPDEKPYSEEESRRVRR------NKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
A E P + R + + G GP K G G G
Sbjct: 966 GA--------EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG 1017
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT----------------------VMGPPGPPGPPG 224
PPGP GPPG GP G PG G PG G PGPPG PG
Sbjct: 1018 PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1077
Query: 225 PQGPPGLQGPSGAADKAG 242
P GP G QG G A G
Sbjct: 1078 PAGPTGKQGDRGEAGAQG 1095
Score = 68.2 bits (165), Expect = 1e-11
Identities = 61/192 (31%), Positives = 73/192 (38%), Gaps = 18/192 (9%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R GA+ G GTPG+ G + G G D G P P PG
Sbjct: 383 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR----- 437
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
G Q A P + + K + +G GP + AG G G
Sbjct: 438 GPPGPQGAT-----GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 492
Query: 187 PPGPPGPPGPQGPP---GIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
G PG GP GPP G PG G PG G GP G PG +GP GL GP GA G
Sbjct: 493 ARGEPGGVGPIGPPGERGAPGNRGFPGQD--GLAGPKGAPGERGPSGLAGPKGANGDPG- 549
Query: 244 RENQPAVVHLQG 255
R +P + +G
Sbjct: 550 RPGEPGLPGARG 561
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/189 (30%), Positives = 72/189 (38%), Gaps = 28/189 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G E + G G PG G + G G + G PK P E G + L G
Sbjct: 486 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----G 540
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+ A + P E ++ G G + K +G PG +G PGP
Sbjct: 541 PKGANGDPGRPGEPGLPG-----------ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 589
Query: 191 PGPPGPQGPPGIPGIPGIPGTT----------VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PGP G +G PG+ G PG G + G PG G PG G G GP G A
Sbjct: 590 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 649
Query: 241 AGTRENQPA 249
AG R Q A
Sbjct: 650 AGERGEQGA 658
Score = 62.8 bits (151), Expect = 5e-10
Identities = 63/211 (29%), Positives = 73/211 (34%), Gaps = 37/211 (17%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSDSQD 129
E G + G G PG G G P P + H G P E G + +S
Sbjct: 256 EAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE-GADGPVKNKKKGKKAGPPGPNGPP 188
P E R +R ++ GA G N + AGPPGP GP
Sbjct: 314 -----------PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 362
Query: 189 GPPG------------------PPGPQGPPGIPGIPGIPGTT-VMGPPGP---PGPPGPQ 226
G PG P G QGP G PG PG PG G PG PG G
Sbjct: 363 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422
Query: 227 GPPGLQGPSGAADKAGTRENQPAVVHLQGQG 257
G PG+ G G G Q A L +G
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 453
Score = 34.7 bits (78), Expect = 0.15
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 10/43 (23%)
Query: 212 TVMGPPGPPGPP----------GPQGPPGLQGPSGAADKAGTR 244
T G PGP G GP+GPPG QGP+G G R
Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDR 137
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 87.4 bits (215), Expect = 2e-17
Identities = 65/198 (32%), Positives = 76/198 (38%), Gaps = 23/198 (11%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E+G G +G+ G G G P P G P QP GE D
Sbjct: 733 EKGEVGPPGPAGSAGARGAPGERGETGPPGP-AGFAGPPGADGQPGAKGEQGEAGQKGDA 791
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
P P + V K ++ +G G + GPPG NG PGP
Sbjct: 792 GAPGPQG---PSGAP-GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGP 847
Query: 191 PGPPGP------------QGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
PGPPGP GPPG G PG+ G GPPG G PG GP G +GP G
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA--GPPGEKGEPGDDGPSGAEGPPGPQ 905
Query: 239 DKAGTRENQPAVVHLQGQ 256
AG R +V L GQ
Sbjct: 906 GLAGQR----GIVGLPGQ 919
Score = 87.4 bits (215), Expect = 2e-17
Identities = 67/205 (32%), Positives = 76/205 (37%), Gaps = 31/205 (15%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G E G G PG G G+ D T +G P P PG A D
Sbjct: 964 EPGREGSPGADGPPGRDGA----AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019
Query: 131 HQMALLNFFFPD----------------EKPYSEEESRRVRRNKRSKSN----EGADGPV 170
+ P +K + E R + R + G GP
Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPS 1079
Query: 171 KNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG-------TTVMGPPGPPGPP 223
++ AGP GP GPPGP GP G G GIPG G PG T GPPG PGPP
Sbjct: 1080 GDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139
Query: 224 GPQGPPGLQGPSGAADKAGTRENQP 248
GP GPPG A G RE P
Sbjct: 1140 GPPGPPGPGIDMSAFAGLGPREKGP 1164
Score = 85.1 bits (209), Expect = 1e-16
Identities = 41/65 (63%), Positives = 42/65 (64%), Gaps = 2/65 (3%)
Query: 180 GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
GP GP GPPGP G PGPQG G PG PG PG V GP GP GPPGP G PG G +G
Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPG--VSGPMGPRGPPGPPGKPGDDGEAGKPG 192
Query: 240 KAGTR 244
KAG R
Sbjct: 193 KAGER 197
Score = 80.9 bits (198), Expect = 2e-15
Identities = 65/203 (32%), Positives = 76/203 (37%), Gaps = 47/203 (23%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R GA+ G G PGT GT G P P + G P + P E G A +
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQ-GPPGLQGMPGERGAAGIAGPKG 696
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPV-------KNKKKGKKAGP 181
D + P+ P + G GP+ N +KG+ GP
Sbjct: 697 DRGDVGEKG---PEGAPGKD-------------GGRGLTGPIGPPGPAGANGEKGE-VGP 739
Query: 182 PGP------------NGPPGPPGPPGPQGPPGIPGIPGIPG----------TTVMGPPGP 219
PGP G GPPGP G GPPG G PG G GP GP
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 799
Query: 220 PGPPGPQGPPGLQGPSGAADKAG 242
G PGPQGP G+ GP GA G
Sbjct: 800 SGAPGPQGPTGVTGPKGARGAQG 822
Score = 78.2 bits (191), Expect = 1e-14
Identities = 61/198 (30%), Positives = 80/198 (40%), Gaps = 31/198 (15%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSD-SQDGH 131
G + G G PG G +G P P G+P + +PG+A G
Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPP----GKPGDDGEAGKPGKAGERGPPGPQGA 205
Query: 132 QMALLNFFFPDEKPY----------SEEESRRVRRNKRSKSNEGADGPVKNK----KKGK 177
+ P K + E + V+ S G+ GP+ + ++G+
Sbjct: 206 RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGR 265
Query: 178 K-----AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPG-------TTVMGPPGPPGPPGP 225
AG G +G PGP GPPGP GP G PG PG PG T GP G GP G
Sbjct: 266 TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGE 325
Query: 226 QGPPGLQGPSGAADKAGT 243
G PG GP+GA+ GT
Sbjct: 326 PGTPGSPGPAGASGNPGT 343
Score = 77.4 bits (189), Expect = 2e-14
Identities = 61/178 (34%), Positives = 68/178 (38%), Gaps = 19/178 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G R G +G G G G P P+ G P P GEA G +
Sbjct: 261 GERGRTGPAGAAGARGNDGQPGPAGPPGPV-GPAGGPGFPGAPGAKGEAG--PTGARGPE 317
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKA-----GPPGPNG 186
A + P E + + N G DG P G G PGP G
Sbjct: 318 GA--------QGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 369
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
PPGP G GP GP G G PGI G G GP G PGP GP G GP+G K G R
Sbjct: 370 PPGPQGATGPLGPKGQTGEPGIAG--FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425
Score = 77.4 bits (189), Expect = 2e-14
Identities = 75/243 (30%), Positives = 90/243 (37%), Gaps = 53/243 (21%)
Query: 13 PAAAPRERGSQGC----GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSEL 68
P AP ERG G G G P R GE GL A L +
Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEP----------GLPGARGL----------TGR 496
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
+ G + ++G SG PG G G +G P PK EPG+A
Sbjct: 497 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ-PGVMGFPGPKGANGEPGKAG------ 549
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE----GADGPVKNKKKGKKAGPPGP 184
EK R K ++ G GP + + GP G
Sbjct: 550 --------------EKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 595
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPP---GLQGPSGAADK 240
G PGPPGPPG G PG G+PG G ++GP G G PG +G P GLQGP G
Sbjct: 596 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 655
Query: 241 AGT 243
GT
Sbjct: 656 PGT 658
Score = 74.7 bits (182), Expect = 1e-13
Identities = 45/93 (48%), Positives = 50/93 (53%), Gaps = 11/93 (11%)
Query: 156 RNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGI------P 209
R K +G G +K+ K GPPGP GP G GP G +G G G PG P
Sbjct: 29 RQPGPKGQKGEPGDIKDIVGPK--GPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86
Query: 210 GTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
GT G PGPPGPPGP GPPGL G + AA AG
Sbjct: 87 GTP--GNPGPPGPPGPPGPPGL-GGNFAAQMAG 116
Score = 74.7 bits (182), Expect = 1e-13
Identities = 63/201 (31%), Positives = 74/201 (36%), Gaps = 37/201 (18%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
RGA+ G +G PG +G + G + G P P + G DS
Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGS-------NGNPGPPGPPGPSGKDGPKGARGDSGPPG 870
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP- 190
+ P P K G DGP GPPGP G G
Sbjct: 871 RAGEPGLQGPAGPP-------------GEKGEPGDDGP------SGAEGPPGPQGLAGQR 911
Query: 191 -----PGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
PG G +G PG+PG G PG G G GPPGP GPPGL GP+G R
Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPG----R 967
Query: 245 ENQPAVVHLQGQGSAIQVKND 265
E P G+ A VK D
Sbjct: 968 EGSPGADGPPGRDGAAGVKGD 988
Score = 74.3 bits (181), Expect = 2e-13
Identities = 60/205 (29%), Positives = 71/205 (34%), Gaps = 42/205 (20%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
LR G + G +G PG +G G P + G P P P PGE D
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP-SGFQGLPGP---PGPPGEGGKPGDQ 614
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+ P R R + + GA G + G GP G
Sbjct: 615 GVPGEAGAPGLVGP----------RGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGA 664
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTT----------------------------VMGPPGP 219
GP GPPG QGPPG+ G+PG G + GP GP
Sbjct: 665 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 724
Query: 220 PGPPGPQGPPGLQGPSGAADKAGTR 244
PGP G G G GP G A AG R
Sbjct: 725 PGPAGANGEKGEVGPPGPAGSAGAR 749
Score = 73.2 bits (178), Expect = 4e-13
Identities = 64/224 (28%), Positives = 79/224 (35%), Gaps = 67/224 (29%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH-----S 125
E+GA G G PGT G +P P G P P P G A
Sbjct: 73 EKGAPGPRGRDGEPGTPG--------NPGPP-----GPPGPPGPPGLGGNFAAQMAGGFD 119
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+ G Q+ ++ + P R + +G G + +GP GP
Sbjct: 120 EKAGGAQLGVM------QGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR 173
Query: 186 GPPGPPG------------------PPGPQGPPGIPGIPGIPGTT--------------- 212
GPPGPPG PPGPQG G PG PG+PG
Sbjct: 174 GPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA 233
Query: 213 ----------VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTREN 246
G G PGP GP+G PG +G +G A AG R N
Sbjct: 234 GAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGN 277
Score = 72.8 bits (177), Expect = 5e-13
Identities = 66/203 (32%), Positives = 77/203 (37%), Gaps = 22/203 (10%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G G +G PG +G G P P G PK Q EPG A + +
Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QGATGPLGPKGQTGEPGIAGFKGEQGPKGE 403
Query: 133 MALLNFFFPDEKPY-SEEESRRVRRNKRS-------KSNEGADG----PVKNKKKGKKAG 180
P P + EE +R R + GA G P ++ G K G
Sbjct: 404 PGPAG---PQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK-G 459
Query: 181 PPGPNGPPGPPGPPGPQGPPGIPGIPGIPG----TTVMGPPGPPGPPGPQGPPGLQGPSG 236
PG GP G GP G G PG PG PG+PG T G GP G GP G PG G G
Sbjct: 460 APGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519
Query: 237 AADKAGTRENQPAVVHLQGQGSA 259
G R QP V+ G A
Sbjct: 520 PPGPQGAR-GQPGVMGFPGPKGA 541
Score = 72.4 bits (176), Expect = 7e-13
Identities = 43/103 (41%), Positives = 49/103 (47%), Gaps = 25/103 (24%)
Query: 165 GADGPVKNK-KKGKKA--GPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTV-------- 213
G GP ++ KG+K GP G +G PG PG PGP GPPG PG PG+ G
Sbjct: 60 GEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFD 119
Query: 214 --------------MGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
MGP GP GPPGP G PG QG G + G
Sbjct: 120 EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162
Score = 71.6 bits (174), Expect = 1e-12
Identities = 61/198 (30%), Positives = 67/198 (33%), Gaps = 39/198 (19%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+ G G PG SG G P G+P + PGE D DG
Sbjct: 840 GSNGNPGPPGPPGPSGKDGPKGARGDSGP-PGRAGEPGLQGPAGPPGEKGEPGD--DGPS 896
Query: 133 MALLNFFFPDEKPYSEEESRRVRR------NKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
A E P + R + + G GP K G G G
Sbjct: 897 GA--------EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRG 948
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTT----------------------VMGPPGPPGPPG 224
PPGP GPPG GP G PG G PG G PGPPG PG
Sbjct: 949 PPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1008
Query: 225 PQGPPGLQGPSGAADKAG 242
P GP G QG G A G
Sbjct: 1009 PAGPTGKQGDRGEAGAQG 1026
Score = 68.2 bits (165), Expect = 1e-11
Identities = 61/192 (31%), Positives = 73/192 (38%), Gaps = 18/192 (9%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSD 126
R GA+ G GTPG+ G + G G D G P P PG
Sbjct: 314 RGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPR----- 368
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
G Q A P + + K + +G GP + AG G G
Sbjct: 369 GPPGPQGAT-----GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRG 423
Query: 187 PPGPPGPPGPQGPP---GIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
G PG GP GPP G PG G PG G GP G PG +GP GL GP GA G
Sbjct: 424 ARGEPGGVGPIGPPGERGAPGNRGFPGQD--GLAGPKGAPGERGPSGLAGPKGANGDPG- 480
Query: 244 RENQPAVVHLQG 255
R +P + +G
Sbjct: 481 RPGEPGLPGARG 492
Score = 67.8 bits (164), Expect = 2e-11
Identities = 58/189 (30%), Positives = 72/189 (38%), Gaps = 28/189 (14%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G E + G G PG G + G G + G PK P E G + L G
Sbjct: 417 GEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----G 471
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+ A + P E ++ G G + K +G PG +G PGP
Sbjct: 472 PKGANGDPGRPGEPGLPG-----------ARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP 520
Query: 191 PGPPGPQGPPGIPGIPGIPGTT----------VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PGP G +G PG+ G PG G + G PG G PG G G GP G A
Sbjct: 521 PGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGP 580
Query: 241 AGTRENQPA 249
AG R Q A
Sbjct: 581 AGERGEQGA 589
Score = 62.8 bits (151), Expect = 5e-10
Identities = 63/211 (29%), Positives = 73/211 (34%), Gaps = 37/211 (17%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSP-ITSHLGQPSPKQQPLEPGEAALHSDSQD 129
E G + G G PG G G P P + H G P E G + +S
Sbjct: 187 EAGKPGKAGERGPPGPQGARGFPG--TPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244
Query: 130 GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE-GADGPVKNKKKGKKAGPPGPNGPP 188
P E R +R ++ GA G N + AGPPGP GP
Sbjct: 245 -----------PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPA 293
Query: 189 GPPG------------------PPGPQGPPGIPGIPGIPGTT-VMGPPGP---PGPPGPQ 226
G PG P G QGP G PG PG PG G PG PG G
Sbjct: 294 GGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 353
Query: 227 GPPGLQGPSGAADKAGTRENQPAVVHLQGQG 257
G PG+ G G G Q A L +G
Sbjct: 354 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKG 384
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 87.0 bits (214), Expect = 3e-17
Identities = 65/191 (34%), Positives = 80/191 (41%), Gaps = 22/191 (11%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G G G+ G +G ++G P P GQP K +P EPG+ D+
Sbjct: 825 GPPGSRGNPGSRGENGPTGAVGFAGPQGPD----GQPGVKGEPGEPGQKG---DAGSPGP 877
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
L P V K + +G G + GPPGP G PGP G
Sbjct: 878 QGLAGSPGP-------HGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAG 930
Query: 193 P---PGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPP---GLQGPSGAADKAGTRE 245
P PG +GPPG+ G PG G GP GPPG PG +G P G GP G AGT
Sbjct: 931 PLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGT-T 989
Query: 246 NQPAVVHLQGQ 256
Q +V + GQ
Sbjct: 990 GQRGIVGMPGQ 1000
Score = 83.6 bits (205), Expect = 3e-16
Identities = 62/188 (32%), Positives = 74/188 (39%), Gaps = 33/188 (17%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
E G E G GTPG G + G P G P + P PG D+
Sbjct: 1045 EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPA----GLPGSQGAPGTPGPVGAPGDAGQR 1100
Query: 131 HQMALLNFFFPDEK-----------PYSEEESRRVRRNKRSKSNEGADG-------PVKN 172
P + P ++ R ++ K + G G P N
Sbjct: 1101 GDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPN 1160
Query: 173 KKKGKKAGPPGPNGPPGPPGP---------PGPQGPPGIPGIPGIPGTT-VMGPPGPPGP 222
++G AG PGP GP GPPGP PGP GP G PG+ G G GPPG PGP
Sbjct: 1161 GEQGS-AGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGP 1219
Query: 223 PGPQGPPG 230
PGP GPPG
Sbjct: 1220 PGPPGPPG 1227
Score = 81.6 bits (200), Expect = 1e-15
Identities = 62/190 (32%), Positives = 76/190 (40%), Gaps = 21/190 (11%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGH 131
+G R G G PG G + G P+ + LG P +P PG + Q G
Sbjct: 557 QGDPGRPGEPGLPGARGLTGNPGVQGPEGKL-GPLGAPGEDGRPGPPGSIGIRG--QPG- 612
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ P K S + + N G G K + GP GP GPPG
Sbjct: 613 -----SMGLPGPKGSSGDPGK-----PGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662
Query: 192 GPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTREN----- 246
G G QGPPG G G+PG GPPG G PG QG PG G G G R N
Sbjct: 663 GERGEQGPPGPTGFQGLPGPP--GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720
Query: 247 QPAVVHLQGQ 256
+P + L G+
Sbjct: 721 EPGITGLPGE 730
Score = 80.9 bits (198), Expect = 2e-15
Identities = 58/186 (31%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSP--ITSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G + +G G+ G +G +G + P P + G+ P+ P G+ H
Sbjct: 309 GPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAP---GQRGAHGMPGKP 365
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
M L P + K GA GP + + + GPPGP G PG
Sbjct: 366 GPMGPLGI--PGSSGFPGNPGM-----KGEAGPTGARGPEGPQGQRGETGPPGPVGSPGL 418
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQPAV 250
PG G G PG G G PGT+ GPPG GPPG GP G GP G + G P V
Sbjct: 419 PGAIGTDGTPGAKGPTGSPGTS--GPPGSAGPPGSPGPQGSTGPQGIRGQPG----DPGV 472
Query: 251 VHLQGQ 256
+G+
Sbjct: 473 PGFKGE 478
Score = 80.5 bits (197), Expect = 2e-15
Identities = 61/202 (30%), Positives = 76/202 (37%), Gaps = 51/202 (25%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
L+ RG + G +G PG++G + G P LG+P + P G+ H
Sbjct: 895 LKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGP-AGPLGEPGKEGPPGLRGDPGSHGRV 953
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
D + G G +K + G PGP+GP
Sbjct: 954 GD-------------------------------RGPAGPPGGPGDKGDPGEDGQPGPDGP 982
Query: 188 PGP------------PGPPGPQGPPGIPGIPGIPG-------TTVMGPPGPPGPPGPQGP 228
PGP PG G +G PG+PG G PG T GPPGP GPPG GP
Sbjct: 983 PGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGP 1042
Query: 229 PGLQGPSGAADKAGTRENQPAV 250
G GP G A GT AV
Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAV 1064
Score = 80.1 bits (196), Expect = 3e-15
Identities = 60/193 (31%), Positives = 70/193 (36%), Gaps = 37/193 (19%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G + +G SG G G G P P T G P P P E G+ D
Sbjct: 645 GKDGEVGPSGPVGPPGLAGERGEQGPPGP-TGFQGLPGPPGPPGEGGKPGDQGVPGDPGA 703
Query: 133 MALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPPG 192
+ L R R N + G G K GP GP G PGP G
Sbjct: 704 VGPLG-------------PRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG 750
Query: 193 PPGPQGPPGIPGIPGIPGTTVMGPPGPPGP---------------------PGPQGPPGL 231
PG GPPG+ G+PG G + G PGP G PGP GPPG
Sbjct: 751 TPGDTGPPGLQGMPGERG--IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGP 808
Query: 232 QGPSGAADKAGTR 244
GP+G + G R
Sbjct: 809 AGPTGEKGEPGPR 821
Score = 77.4 bits (189), Expect = 2e-14
Identities = 60/180 (33%), Positives = 69/180 (38%), Gaps = 19/180 (10%)
Query: 71 ERGAESRLGGSGTPGTSGTLSSLGGLDP-----DSPITSHLGQPSPKQQPLEPGEAALHS 125
E G E G G PG+ G + G P D GQP P P G
Sbjct: 934 EPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTG--- 990
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
Q ++ P ++ E + + G G +K GPPG N
Sbjct: 991 ------QRGIVGM--PGQR--GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSN 1040
Query: 186 GPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP G PGP GP G G PG G G G PGP G PG QG PG GP GA AG R
Sbjct: 1041 GPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQR 1100
Score = 76.6 bits (187), Expect = 3e-14
Identities = 61/179 (34%), Positives = 70/179 (39%), Gaps = 24/179 (13%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG-------EAALHS 125
G RLG G PG G G P P LG P P PG A
Sbjct: 342 GERGRLGPQGAPGQRGAHGMPGKPGPMGP----LGIPGSSGFPGNPGMKGEAGPTGARGP 397
Query: 126 DSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPN 185
+ G + + P S + + GA GP + +GPPG
Sbjct: 398 EGPQGQR--------GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT---SGPPGSA 446
Query: 186 GPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GPPG PGP G GP GI G PG PG V G G GP G GP G+QGP G + G R
Sbjct: 447 GPPGSPGPQGSTGPQGIRGQPGDPG--VPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR 503
Score = 76.6 bits (187), Expect = 3e-14
Identities = 57/176 (32%), Positives = 68/176 (38%), Gaps = 25/176 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R ERG G G G G GG PD P G P P P + G L
Sbjct: 710 RGERGNPGERGEPGITGLPGEKGMAGGHGPDGP----KGSPGPSGTPGDTGPPGLQG--- 762
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
P E+ + + R +GA+G N G PGP GPP
Sbjct: 763 -----------MPGERGIAGTPGPKGDRG--GIGEKGAEGTAGNDGA---RGLPGPLGPP 806
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR 244
GP GP G +G PG G+ G PG+ G PG G GP G G GP G + G +
Sbjct: 807 GPAGPTGEKGEPGPRGLVGPPGS--RGNPGSRGENGPTGAVGFAGPQGPDGQPGVK 860
Score = 76.6 bits (187), Expect = 3e-14
Identities = 64/203 (31%), Positives = 75/203 (36%), Gaps = 41/203 (20%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPG-EAALHSDS 127
R ERG G +GTPG G + G P P+ G P EPG E +D
Sbjct: 1001 RGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV----GPPGSNGPVGEPGPEGPAGNDG 1056
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
G A+ + S+ G GPV + G PG GP
Sbjct: 1057 TPGRDGAV--------GERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGP 1108
Query: 188 PGPPGP------PGPQGP---------------------PGIPGIPGIPGTT-VMGPPGP 219
GPPG PGPQGP G+ G+PG PG G G
Sbjct: 1109 IGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGI 1168
Query: 220 PGPPGPQGPPGLQGPSGAADKAG 242
PGP GP+GPPG GPSG G
Sbjct: 1169 PGPFGPRGPPGPVGPSGKEGNPG 1191
Score = 72.8 bits (177), Expect = 5e-13
Identities = 63/188 (33%), Positives = 73/188 (38%), Gaps = 34/188 (18%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG-----------GLDPDSPITSHLGQPSPKQQPLEPGEA 121
G R G +G PG+ G G G+D + + G P P P PG
Sbjct: 126 GIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPD 185
Query: 122 ALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP 181
L QMA L DEK +V S G GP + + AGP
Sbjct: 186 GLSRPFSA--QMAGL-----DEK---SGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP 235
Query: 182 PGPNGPPGPPGP------PGPQGPPGIPGIPGIPGTT-------VMGPPGPPGPPGPQGP 228
GP G PG PGP GP+GPPG PG G PG G PG G PG G
Sbjct: 236 TGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGL 295
Query: 229 PGLQGPSG 236
PGL+G G
Sbjct: 296 PGLKGHRG 303
Score = 72.4 bits (176), Expect = 7e-13
Identities = 62/215 (28%), Positives = 78/215 (36%), Gaps = 59/215 (27%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQ 128
R +G + + GG+G G G G + P +G P+ P +PGE D +
Sbjct: 221 RGPQGLQGQQGGAGPTGPPGEPGDPGPMGP-------IGSRGPEGPPGKPGE-----DGE 268
Query: 129 DGHQMALLNFFFPDEKPYSEEESRR----------VRRNKRSKSNEGADGPVKNKKKGKK 178
G P E ++ R ++ ++ K EG G V +
Sbjct: 269 PGRNGN------PGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGE 322
Query: 179 AGPPGPNGPPGP---------------------------PGPPGPQGPPGIPGIPGIPGT 211
AGP GP G GP PG PGP GP GIPG G PG
Sbjct: 323 AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382
Query: 212 TVM----GPPGPPGPPGPQGPPGLQGPSGAADKAG 242
M GP G GP GPQG G GP G G
Sbjct: 383 PGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417
Score = 67.8 bits (164), Expect = 2e-11
Identities = 64/196 (32%), Positives = 72/196 (36%), Gaps = 21/196 (10%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPD-SPITSHLGQPSPKQQPLEPGEAALHSDS 127
R E G +G G PG GT + G P SP TS G P P PG
Sbjct: 404 RGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTS--GPPGSAGPPGSPGP-----QG 456
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGP---PGP 184
G Q P + E K G GP+ + K GP PG
Sbjct: 457 STGPQGIRGQPGDPGVPGFKGEAGP-----KGEPGPHGIQGPIGPPGEEGKRGPRGDPGT 511
Query: 185 NGPPGPPGPPGPQGPPGIPGIPGIPGTT----VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
GPPGP G G G G PG G+PG GP G GP G QG PG G G
Sbjct: 512 VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGA 571
Query: 241 AGTRENQPAVVHLQGQ 256
G N P V +G+
Sbjct: 572 RGLTGN-PGVQGPEGK 586
Score = 67.4 bits (163), Expect = 2e-11
Identities = 52/173 (30%), Positives = 59/173 (34%), Gaps = 35/173 (20%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSDSQDG 130
G G G PG G G P+ P G P P P PG A+ +D G
Sbjct: 372 GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG--AIGTDGTPG 429
Query: 131 HQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGP 190
+K G+ G G PGP G GP
Sbjct: 430 -----------------------------AKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP 460
Query: 191 PGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGT 243
G G G PG+PG G G G PGP G GP GPPG +G G GT
Sbjct: 461 QGIRGQPGDPGVPGFKGEAGP--KGEPGPHGIQGPIGPPGEEGKRGPRGDPGT 511
Score = 66.2 bits (160), Expect = 5e-11
Identities = 57/197 (28%), Positives = 71/197 (36%), Gaps = 30/197 (15%)
Query: 73 GAESRLGGSGTPGTSGTLSSLG-----GLDPDSPITSHLGQPSPKQQPLE---------P 118
G G +G PG+ G S G G D + G+ PK +P P
Sbjct: 438 GTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPP 497
Query: 119 GEAALHSDSQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKK 178
GE D + P R N+ ++G GP + +
Sbjct: 498 GEEGKRGPRGDPGTVG----------PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGP 547
Query: 179 AGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAA 238
G GP G G PG PG G PG G+ G PG V GP G GP G G G GP G+
Sbjct: 548 VGSSGPKGSQGDPGRPGEPGLPGARGLTGNPG--VQGPEGKLGPLGAPGEDGRPGPPGSI 605
Query: 239 DKAGTRENQPAVVHLQG 255
G QP + L G
Sbjct: 606 GIRG----QPGSMGLPG 618
Score = 63.5 bits (153), Expect = 3e-10
Identities = 44/129 (34%), Positives = 52/129 (40%), Gaps = 42/129 (32%)
Query: 156 RNKRSKSNEGADGPVKNKKKGKK--AGPPGPNGP---------PGPPGPPGPQGPPGIPG 204
R ++ + E PV +G+ AGPPG GP PGP GP G G PG+PG
Sbjct: 109 RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPG 168
Query: 205 IPGIPG----TTVMGP---------------------------PGPPGPPGPQGPPGLQG 233
PG PG + GP PG GP GP+GP GLQG
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228
Query: 234 PSGAADKAG 242
G A G
Sbjct: 229 QQGGAGPTG 237
Score = 62.8 bits (151), Expect = 5e-10
Identities = 54/181 (29%), Positives = 66/181 (36%), Gaps = 27/181 (14%)
Query: 79 GGSGTPGTSGTLSSLG-----GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQM 133
G +G PG +G L G GL D +G P P PG+ +DG
Sbjct: 921 GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG--DPGEDGQPG 978
Query: 134 ALLNFFFPDEKPYSEEESRR-----VRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
PD P + + + + + G GP K G G GPP
Sbjct: 979 -------PDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPP 1031
Query: 189 GPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
GP GPPG GP G PG G P G G PG G G +G G AG +Q
Sbjct: 1032 GPVGPPGSNGPVGEPGPEG--------PAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083
Query: 249 A 249
A
Sbjct: 1084 A 1084
Score = 36.2 bits (82), Expect = 0.052
Identities = 29/80 (36%), Positives = 35/80 (43%), Gaps = 11/80 (13%)
Query: 181 PPGPNGP-----PGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGP---QGPPGLQ 232
PPG P PG +G G G PG+ V G G PGP GP QGP G +
Sbjct: 88 PPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLV-PVVTGIRGRPGPAGPPGSQGPRGER 146
Query: 233 GPSGAADKAGTR--ENQPAV 250
GP G G + + +P V
Sbjct: 147 GPKGRPGPRGPQGIDGEPGV 166
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 87.0 bits (214), Expect = 3e-17
Identities = 80/236 (33%), Positives = 90/236 (38%), Gaps = 32/236 (13%)
Query: 13 PAAAPRERGSQGC-GCGGAPARAG----EGNSCLLFLGFFGLSLALHLLTLCCYLELRSE 67
P+ P ++GS G G G P G +G S LL G L LA + C
Sbjct: 514 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINL-LAKDVCNDCP--PGPPG 570
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
L G + G G PG GT G P + G P+ E G
Sbjct: 571 LPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG-LPGPPGIAGPQGSQGERGADGEVGQK 629
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
D + F P P GADG AGPPG G
Sbjct: 630 GDQGHPGVPGFMGPPGNP----------------GPPGADGIAG------AAGPPGIQGS 667
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTTVM-GPPGPPGPPGPQGPPGLQGPSGAADKAG 242
PG GPPGPQGP G+PGIPG G G PGPPG PG G PGL GP GA G
Sbjct: 668 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 723
Score = 81.6 bits (200), Expect = 1e-15
Identities = 58/180 (32%), Positives = 76/180 (42%), Gaps = 15/180 (8%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS----Q 128
G + G G PG G S L G+ + G+P P +P + GE L
Sbjct: 663 GIQGSPGKEGPPGPQGP-SGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGP 721
Query: 129 DGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPP 188
G + + P P E + + + +G GP + GPPG NG P
Sbjct: 722 PGFKGHTGDSGAPG--PRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779
Query: 189 GPPGPPGPQGPPGIP------GIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAG 242
G PG PGP G PG G PG+PG +GP GPPG PG +G PG +G G + G
Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGSPGLPG--FLGPRGPPGEPGEKGVPGKEGVPGKPGEPG 837
Score = 81.3 bits (199), Expect = 1e-15
Identities = 66/183 (36%), Positives = 81/183 (44%), Gaps = 35/183 (19%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALH-SDSQDGH 131
GA+ + G G PG +G +P +P H+G P P P G L + +DG
Sbjct: 383 GAKGQEGAHGAPGAAG--------NPGAP--GHVGAPGPSGPPGSVGAPGLRGTPGKDGE 432
Query: 132 QMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
+ EK + EE R + GA G KGK G PG G PG P
Sbjct: 433 R---------GEKGAAGEEGSPGPVGPRG--DPGAPGLPGPPGKGKD-GEPGLRGSPGLP 480
Query: 192 GPPGPQGPPGIPGIPGIPGTT------VMGPPGP---P---GPPGPQGPPGLQGPSGAAD 239
GP G +G G PGIPG PG+ V GPPGP P G PG +G PG GP G A
Sbjct: 481 GPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG 540
Query: 240 KAG 242
+ G
Sbjct: 541 RDG 543
Score = 77.4 bits (189), Expect = 2e-14
Identities = 60/197 (30%), Positives = 75/197 (38%), Gaps = 41/197 (20%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
+R E+G + G G PG G G P P P PG +L
Sbjct: 296 VRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGP-------------PGLPGTTSL---- 338
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
F P + E+ K K + G G + + + GP GP GP
Sbjct: 339 -----------FTPHPRMPGEQGP------KGEKGDPGLPGEPGLQGRPGELGPQGPTGP 381
Query: 188 PGPPGPPGPQGPPGIPGIPGIPGTTVMGPPGPPGPPGPQGPPGLQGPSGAADKAGTR--- 244
PG G G G PG G PG PG +G PGP GPPG G PGL+G G + G +
Sbjct: 382 PGAKGQEGAHGAPGAAGNPGAPGH--VGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAA 439
Query: 245 --ENQPAVVHLQGQGSA 259
E P V +G A
Sbjct: 440 GEEGSPGPVGPRGDPGA 456
Score = 75.5 bits (184), Expect = 8e-14
Identities = 61/203 (30%), Positives = 74/203 (36%), Gaps = 46/203 (22%)
Query: 68 LRRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDS 127
L+ +RG + G +G PG GT S P + G K P PGE L
Sbjct: 314 LKGDRGEKGEAGPAGPPGLPGTTSLF---TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRP 370
Query: 128 QDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGP 187
+ L P P + K + GA G N G PGP+GP
Sbjct: 371 GE------LGPQGPTGPPGA----------KGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 414
Query: 188 PGP---------------------------PGPPGPQGPPGIPGIPGIPGTTVMGPPGPP 220
PG PGP GP+G PG PG+PG PG G PG
Sbjct: 415 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLR 474
Query: 221 GPPGPQGPPGLQGPSGAADKAGT 243
G PG GP G +G GA G+
Sbjct: 475 GSPGLPGPLGTKGDRGAPGIPGS 497
Score = 74.3 bits (181), Expect = 2e-13
Identities = 64/195 (32%), Positives = 71/195 (36%), Gaps = 28/195 (14%)
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGLDPDSPI--TSHLGQPSPKQQPLEPGEAALHSD 126
R E GA G G PG G G P P G P +P G
Sbjct: 737 RGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGS 796
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L F P P E K EG G K G PG G
Sbjct: 797 KGENGSPGLPGFLGPRGPPGEPGE-------KGVPGKEGVPG---------KPGEPGFKG 840
Query: 187 PPGPPGPPGPQGPP---GIPGIPGIPG----TTVMGPPGPPGPPGPQGPPGLQGPSGAAD 239
G PG G +GPP G PG PGIPG T +MGP G PG GP GPP GP G
Sbjct: 841 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPP---GPPGQPG 897
Query: 240 KAGTRENQPAVVHLQ 254
G R P++ L+
Sbjct: 898 FPGLRGESPSMETLR 912
Score = 73.9 bits (180), Expect = 2e-13
Identities = 62/200 (31%), Positives = 78/200 (39%), Gaps = 35/200 (17%)
Query: 72 RGAESRLGGSGTPGTSGTLSSLG--GLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQD 129
+G + GG G PG G G GL + G P P +PG L +S
Sbjct: 848 KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPS 907
Query: 130 ------------GHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNE----GADGPVKNK 173
G Q+ + + P + +S + R + G GP+
Sbjct: 908 METLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEP 967
Query: 174 KKGKKAGPPGPNGPPGP---------PGPPG-----PQGPPGIPGIPGIPGTTVMGPPGP 219
+ + G GP+GP GP PG PG GPPGIPG PG PG G PG
Sbjct: 968 GRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGI 1027
Query: 220 PGPPGPQGP---PGLQGPSG 236
PGP G GP PGL GP G
Sbjct: 1028 PGPQGETGPAGHPGLPGPPG 1047
Score = 72.8 bits (177), Expect = 5e-13
Identities = 62/189 (32%), Positives = 75/189 (39%), Gaps = 39/189 (20%)
Query: 81 SGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQMALLNFFF 140
+G PG G GL + +G+ +P E GEA L F
Sbjct: 249 NGEPGERGE----DGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPG-----------F 293
Query: 141 PDEKPYSEEESRRVRRNKRSKSNEGADG-PVKNKKKGKKAGPPGPNGPPGPPGP------ 193
P VR K + +G G P +G+K G GP GPPG PG
Sbjct: 294 PG-----------VRGEKGDQGEKGELGLPGLKGDRGEK-GEAGPAGPPGLPGTTSLFTP 341
Query: 194 ----PGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADKAGTRENQP 248
PG QGP G G PG+PG + G PG GP GP GPPG +G GA G N
Sbjct: 342 HPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPG 401
Query: 249 AVVHLQGQG 257
A H+ G
Sbjct: 402 APGHVGAPG 410
Score = 65.9 bits (159), Expect = 6e-11
Identities = 62/224 (27%), Positives = 75/224 (33%), Gaps = 67/224 (29%)
Query: 73 GAESRLGGSGTPGTSGTLSSLGGLDPDSPITSHLGQPSPKQQPLEPGEAALHSDSQDGHQ 132
G+ G SGTPG G+ G P P G P+ P EPGE + +
Sbjct: 780 GSPGEPGPSGTPGQKGSKGENGS--PGLP-----GFLGPRGPPGEPGEKGVPGKEGVPGK 832
Query: 133 MALLNFFFPDEKPYSEEESRR-VRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNGPPGPP 191
P E + E ++ +K +G G G GP G PG
Sbjct: 833 --------PGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGEN 884
Query: 192 GPPGPQGPPGIPGIPGIPGTTV------------------------------------MG 215
GP GP GPPG PG PG+ G + G
Sbjct: 885 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 944
Query: 216 PPGPPGPPGPQGPPG---------------LQGPSGAADKAGTR 244
PGPPGPPG G PG L+GPSG G R
Sbjct: 945 RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGER 988
Score = 39.3 bits (90), Expect = 0.006
Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 1/64 (1%)
Query: 182 PGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPPGPQGPPGLQGPSGAADK 240
PG G PG G G PG PG+ G G + G PG G G G PG G G
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 302
Query: 241 AGTR 244
G +
Sbjct: 303 QGEK 306
Score = 38.5 bits (88), Expect = 0.011
Identities = 56/210 (26%), Positives = 69/210 (32%), Gaps = 19/210 (9%)
Query: 13 PAAAPRERGSQGC----GCGGAPARAGEGNSCLLFLGFFGLSLALHLLTLCCYLELRSEL 68
P P E G G G G P GE S L L T YL +
Sbjct: 877 PQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPP 936
Query: 69 RRERGAESRLGGSGTPGTSGTLSSLGGL-DPDSPITSHLGQPSPKQQPLEP-GEAALHSD 126
+ ++ R G G PG G G + +P P L PS P+ P GE D
Sbjct: 937 AYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSG---PIGPKGERGAKGD 993
Query: 127 SQDGHQMALLNFFFPDEKPYSEEESRRVRRNKRSKSNEGADGPVKNKKKGKKAGPPGPNG 186
+ L P P E + +G G + + AG PG G
Sbjct: 994 P-GAPGVGLRGEMGPPGIPGQPGEP--------GYAKDGLPGIPGPQGETGPAGHPGLPG 1044
Query: 187 PPGPPGPPGPQGPPGIPGIPGIPGTTVMGP 216
PPGPPG P + PG V GP
Sbjct: 1045 PPGPPGQCDPSQCAYFASLAARPG-NVKGP 1073
Score = 37.0 bits (84), Expect = 0.031
Identities = 25/84 (29%), Positives = 33/84 (39%), Gaps = 1/84 (1%)
Query: 165 GADGPVKNKKKGKKAGPPGPNGPPGPPGPPGPQGPPGIPGIPGIPGTT-VMGPPGPPGPP 223
G GP + + + PG G G G G+PG PG +G G G P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279
Query: 224 GPQGPPGLQGPSGAADKAGTRENQ 247
G +G GL G G G + +Q
Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQ 303
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.137 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,584,297
Number of Sequences: 37866
Number of extensions: 1738490
Number of successful extensions: 67632
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 712
Number of HSP's successfully gapped in prelim test: 1071
Number of HSP's that attempted gapping in prelim test: 11592
Number of HSP's gapped (non-prelim): 12827
length of query: 391
length of database: 18,247,518
effective HSP length: 104
effective length of query: 287
effective length of database: 14,309,454
effective search space: 4106813298
effective search space used: 4106813298
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.