Search of human proteins with 40806173

Search of human proteins with 40806173

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]
         (489 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]             977   0.0  
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              877   0.0  
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            217   2e-56
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      156   4e-38
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       156   4e-38
gi|6005942 valosin-containing protein [Homo sapiens]                  123   3e-28
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              117   3e-26
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           111   1e-24
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   110   4e-24
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            110   4e-24
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   110   4e-24
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   110   4e-24
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 109   5e-24
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 109   5e-24
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             108   8e-24
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       106   5e-23
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           105   1e-22
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            104   2e-22
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            103   4e-22
gi|4505725 peroxin1 [Homo sapiens]                                     89   9e-18
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]               86   8e-17
gi|31742536 fidgetin-like 1 [Homo sapiens]                             84   4e-16
gi|112789543 fidgetin-like 1 [Homo sapiens]                            84   4e-16
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                      80   4e-15
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]                80   4e-15
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]                80   4e-15
gi|40806170 spastin isoform 2 [Homo sapiens]                           79   1e-14
gi|11875211 spastin isoform 1 [Homo sapiens]                           79   1e-14
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]          77   5e-14
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]           70   3e-12

>gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]
          Length = 489

 Score =  977 bits (2525), Expect = 0.0
 Identities = 489/489 (100%), Positives = 489/489 (100%)

Query: 1   MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL 60
           MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
Sbjct: 1   MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL 60

Query: 61  QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA 120
           QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
Sbjct: 61  QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA 120

Query: 121 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV 180
           PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
Sbjct: 121 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV 180

Query: 181 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR 240
           QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
Sbjct: 181 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR 240

Query: 241 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG 300
           IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
Sbjct: 241 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG 300

Query: 301 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK 360
           KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
Sbjct: 301 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK 360

Query: 361 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT 420
           AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
Sbjct: 361 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT 420

Query: 421 MSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGTMRKLRGKTPACSCLTEPTGSRRAMEGH 480
           MSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGTMRKLRGKTPACSCLTEPTGSRRAMEGH
Sbjct: 421 MSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGTMRKLRGKTPACSCLTEPTGSRRAMEGH 480

Query: 481 SLCWGCLLH 489
           SLCWGCLLH
Sbjct: 481 SLCWGCLLH 489


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  877 bits (2265), Expect = 0.0
 Identities = 442/442 (100%), Positives = 442/442 (100%)

Query: 1   MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL 60
           MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL
Sbjct: 1   MAVLLLLLRALRRGPGPGPRPLWGPGPAWSPGFPARPGRGRPYMASRPPGDLAEAGGRAL 60

Query: 61  QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA 120
           QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA
Sbjct: 61  QSLQLRLLTPTFEGINGLLLKQHLVQNPVRLWQLLGGTFYFNTSRLKQKNKEKDKSKGKA 120

Query: 121 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV 180
           PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV
Sbjct: 121 PEEDEEERRRRERDDQMYRERLRTLLVIAVVMSLLNALSTSGGSISWNDFVHEMLAKGEV 180

Query: 181 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR 240
           QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR
Sbjct: 181 QRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVANIDKFEEKLRAAEDELNIEAKDR 240

Query: 241 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG 300
           IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG
Sbjct: 241 IPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLAGMTGREGGFSAFNQLKMARFTIVDG 300

Query: 301 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK 360
           KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK
Sbjct: 301 KMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAK 360

Query: 361 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT 420
           AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT
Sbjct: 361 AVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTT 420

Query: 421 MSGFSNTEEEQTLNQLLVEMDG 442
           MSGFSNTEEEQTLNQLLVEMDG
Sbjct: 421 MSGFSNTEEEQTLNQLLVEMDG 442


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  217 bits (553), Expect = 2e-56
 Identities = 134/289 (46%), Positives = 172/289 (59%), Gaps = 15/289 (5%)

Query: 158 LSTSGGSISWNDFVHEMLAKGEVQRVQVVPESDVVEVYLHPGAVVFGRPRLALMYRMQVA 217
           L  SG  I+W DFV+  L+KG V R++VV +   V V   PG      P         + 
Sbjct: 163 LKRSGREITWKDFVNNYLSKGVVDRLEVVNKR-FVRVTFTPGKT----PVDGQYVWFNIG 217

Query: 218 NIDKFEEKLRAAEDELNIEAKDRIPVSYKRTGFFGNALYSVGMTAVGLAILWYVFRLA-- 275
           ++D FE  L   + EL IE ++R+PV Y      G+ L S+  T + +A L Y  R    
Sbjct: 218 SVDTFERNLETLQQELGIEGENRVPVVYIAESD-GSFLLSMLPTVLIIAFLLYTIRRGPA 276

Query: 276 --GMTGREGGFSAFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPER 333
             G TGR  G        +   T    K    V FKDVAG  EAKLE+ EFV++LK+P++
Sbjct: 277 GIGRTGRGMG----GLFSVGETTAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNFLKNPKQ 332

Query: 334 FLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSL 393
           +  LGAK+PKGA+L GPPG GKTLLAKA A EA VPF+ ++G EF+E+  G+G ARVR L
Sbjct: 333 YQDLGAKIPKGAILTGPPGTGKTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDL 392

Query: 394 FKEARARAPCIVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDG 442
           F  AR  APCI++IDEIDAVG+KR     G   +E+E TLNQLLVEMDG
Sbjct: 393 FALARKNAPCILFIDEIDAVGRKRGRGNFG-GQSEQENTLNQLLVEMDG 440


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  156 bits (395), Expect = 4e-38
 Identities = 80/146 (54%), Positives = 109/146 (74%), Gaps = 5/146 (3%)

Query: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357
           VD    K V+F+ V G+ EAK E++E V++LK+P++F  LG K+PKG LL+GPPG GKTL
Sbjct: 328 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 387

Query: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417
           LA+AVA EA VPF   +G EF E+  G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR
Sbjct: 388 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 447

Query: 418 -STTMSGFSNTEEEQTLNQLLVEMDG 442
             + M  +S     QT+NQLL EMDG
Sbjct: 448 IESPMHPYS----RQTINQLLAEMDG 469


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  156 bits (395), Expect = 4e-38
 Identities = 80/146 (54%), Positives = 109/146 (74%), Gaps = 5/146 (3%)

Query: 298 VDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTL 357
           VD    K V+F+ V G+ EAK E++E V++LK+P++F  LG K+PKG LL+GPPG GKTL
Sbjct: 271 VDPVQMKNVTFEHVKGVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTL 330

Query: 358 LAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKR 417
           LA+AVA EA VPF   +G EF E+  G+GA+R+R+LF+EA+A APC+++IDE+D+VG KR
Sbjct: 331 LARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKR 390

Query: 418 -STTMSGFSNTEEEQTLNQLLVEMDG 442
             + M  +S     QT+NQLL EMDG
Sbjct: 391 IESPMHPYS----RQTINQLLAEMDG 412


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  123 bits (309), Expect = 3e-28
 Identities = 59/140 (42%), Positives = 91/140 (65%), Gaps = 2/140 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V+++D+ G+ + K E++E V Y ++ P++FL+ G    KG L  GPPGCGKTLLAKA+A 
Sbjct: 474 VTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIAN 533

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E Q  F+++ GPE + +  G   A VR +F +AR  APC+++ DE+D++ K R   + G 
Sbjct: 534 ECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNI-GD 592

Query: 425 SNTEEEQTLNQLLVEMDGAS 444
                ++ +NQ+L EMDG S
Sbjct: 593 GGGAADRVINQILTEMDGMS 612



 Score =  102 bits (255), Expect = 6e-22
 Identities = 54/138 (39%), Positives = 79/138 (57%), Gaps = 5/138 (3%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V + D+ G  +   +++E V+  L+ P  F  +G K P+G LL GPPG GKTL+A+AVA 
Sbjct: 201 VGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVAN 260

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E    F  + GPE +  + G   + +R  F+EA   AP I++IDE+DA+  KR  T    
Sbjct: 261 ETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKT---- 316

Query: 425 SNTEEEQTLNQLLVEMDG 442
               E + ++QLL  MDG
Sbjct: 317 HGEVERRIVSQLLTLMDG 334


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  117 bits (292), Expect = 3e-26
 Identities = 59/138 (42%), Positives = 91/138 (65%), Gaps = 3/138 (2%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           VS+ D+ G+   KL++ + V++ LK PE F+++G + PKG LL GPPGC KT++AKA+A 
Sbjct: 624 VSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKALAN 683

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E+ + FLA+ GPE +    G     VR  F++ARA AP I++ DE+DA+  +R +++   
Sbjct: 684 ESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVERGSSLG-- 741

Query: 425 SNTEEEQTLNQLLVEMDG 442
           +    ++ L QLL EMDG
Sbjct: 742 AGNVADRVLAQLLTEMDG 759



 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 53/138 (38%), Positives = 76/138 (55%), Gaps = 5/138 (3%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V++  + G+      +RE ++  LK PE F   G   P+G LL GPPG GKT++A+AVA 
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVAN 409

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E       + GPE +    G   A++R +F EA  R P I++IDE+DA+  KR     G 
Sbjct: 410 EVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKR----EGA 465

Query: 425 SNTEEEQTLNQLLVEMDG 442
            N  E++ +  LL  MDG
Sbjct: 466 QNEVEKRVVASLLTLMDG 483


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  111 bits (278), Expect = 1e-24
 Identities = 65/157 (41%), Positives = 87/157 (55%), Gaps = 3/157 (1%)

Query: 286 AFNQLKMARFTIVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGA 345
           A  QL+ A    V       VS+ DV G+ E K E+ E +         L LG +   G 
Sbjct: 682 ALEQLQTAHSQAVGAPKIPSVSWHDVGGLQEVKKEILETIQLPLEHPELLSLGLR-RSGL 740

Query: 346 LLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIV 405
           LL GPPG GKTLLAKAVATE  + FL++ GPE + +  G     VR +F  ARA APCI+
Sbjct: 741 LLHGPPGTGKTLLAKAVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCII 800

Query: 406 YIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDG 442
           + DE+D++   R    SG S    ++ ++QLL E+DG
Sbjct: 801 FFDELDSLAPSRG--RSGDSGGVMDRVVSQLLAELDG 835



 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 20/72 (27%), Positives = 35/72 (48%)

Query: 346 LLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIV 405
           LL GPPGCGKT +  A  +   +  L +          G    +++++F  AR   P ++
Sbjct: 467 LLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAVL 526

Query: 406 YIDEIDAVGKKR 417
            +  +D +G+ R
Sbjct: 527 LLTAVDLLGRDR 538


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  110 bits (274), Expect = 4e-24
 Identities = 61/138 (44%), Positives = 85/138 (61%), Gaps = 2/138 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V + D+ GM   K EVRE V+  L   E + Q+G   P+G L+ GPPGCGKT+LAKAVA 
Sbjct: 158 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAH 217

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
                F+ + G EFV+   G G   VR +F+ A+  AP I++IDEIDA+  KR    +G 
Sbjct: 218 HTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG- 276

Query: 425 SNTEEEQTLNQLLVEMDG 442
           ++ E ++ L +LL +MDG
Sbjct: 277 ADREVQRILLELLNQMDG 294


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  110 bits (274), Expect = 4e-24
 Identities = 60/137 (43%), Positives = 85/137 (62%), Gaps = 2/137 (1%)

Query: 307 SFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           ++ D+ G+     E++E V+  L  PE + ++G K PKG +L GPPG GKTLLAKAVA +
Sbjct: 183 TYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQ 242

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
               FL + G E ++   G G   VR LF+ A   AP IV+IDEIDA+G KR  + SG  
Sbjct: 243 TSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSG-G 301

Query: 426 NTEEEQTLNQLLVEMDG 442
             E ++T+ +LL ++DG
Sbjct: 302 EREIQRTMLELLNQLDG 318


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  110 bits (274), Expect = 4e-24
 Identities = 61/138 (44%), Positives = 85/138 (61%), Gaps = 2/138 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V + D+ GM   K EVRE V+  L   E + Q+G   P+G L+ GPPGCGKT+LAKAVA 
Sbjct: 131 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAH 190

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
                F+ + G EFV+   G G   VR +F+ A+  AP I++IDEIDA+  KR    +G 
Sbjct: 191 HTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG- 249

Query: 425 SNTEEEQTLNQLLVEMDG 442
           ++ E ++ L +LL +MDG
Sbjct: 250 ADREVQRILLELLNQMDG 267


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  110 bits (274), Expect = 4e-24
 Identities = 61/138 (44%), Positives = 85/138 (61%), Gaps = 2/138 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V + D+ GM   K EVRE V+  L   E + Q+G   P+G L+ GPPGCGKT+LAKAVA 
Sbjct: 162 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAH 221

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
                F+ + G EFV+   G G   VR +F+ A+  AP I++IDEIDA+  KR    +G 
Sbjct: 222 HTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG- 280

Query: 425 SNTEEEQTLNQLLVEMDG 442
           ++ E ++ L +LL +MDG
Sbjct: 281 ADREVQRILLELLNQMDG 298


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  109 bits (273), Expect = 5e-24
 Identities = 59/136 (43%), Positives = 81/136 (59%), Gaps = 4/136 (2%)

Query: 306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           V F+DV G      EV + + +++ PE +  LG   P+G LL GPPGCGKTLLA A+A E
Sbjct: 156 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 215

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
             +P L +A PE V  + G    ++R LF++A + APCI++IDEIDA+  KR       S
Sbjct: 216 LDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA----S 271

Query: 426 NTEEEQTLNQLLVEMD 441
              E + + QLL  MD
Sbjct: 272 KDMERRIVAQLLTCMD 287



 Score =  107 bits (268), Expect = 2e-23
 Identities = 56/143 (39%), Positives = 88/143 (61%), Gaps = 5/143 (3%)

Query: 306 VSFKDVAGMHEAKLEVR-EFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V++ D+  + + + E+    +  +++P++F  LG   P G LL GPPGCGKTLLAKAVA 
Sbjct: 472 VTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVAN 531

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E+ + F+++ GPE + +  G     VR +F+ A+  APC+++ DE+DA+  +RS   +G 
Sbjct: 532 ESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETGA 591

Query: 425 SNTEEEQTLNQLLVEMDGASLDQ 447
           S     + +NQLL EMDG    Q
Sbjct: 592 S----VRVVNQLLTEMDGLEARQ 610


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  109 bits (273), Expect = 5e-24
 Identities = 59/136 (43%), Positives = 81/136 (59%), Gaps = 4/136 (2%)

Query: 306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           V F+DV G      EV + + +++ PE +  LG   P+G LL GPPGCGKTLLA A+A E
Sbjct: 262 VKFEDVGGNDMTLKEVCKMLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGE 321

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
             +P L +A PE V  + G    ++R LF++A + APCI++IDEIDA+  KR       S
Sbjct: 322 LDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA----S 377

Query: 426 NTEEEQTLNQLLVEMD 441
              E + + QLL  MD
Sbjct: 378 KDMERRIVAQLLTCMD 393



 Score =  107 bits (268), Expect = 2e-23
 Identities = 56/143 (39%), Positives = 88/143 (61%), Gaps = 5/143 (3%)

Query: 306 VSFKDVAGMHEAKLEVR-EFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V++ D+  + + + E+    +  +++P++F  LG   P G LL GPPGCGKTLLAKAVA 
Sbjct: 578 VTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAVAN 637

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           E+ + F+++ GPE + +  G     VR +F+ A+  APC+++ DE+DA+  +RS   +G 
Sbjct: 638 ESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRETGA 697

Query: 425 SNTEEEQTLNQLLVEMDGASLDQ 447
           S     + +NQLL EMDG    Q
Sbjct: 698 S----VRVVNQLLTEMDGLEARQ 716


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  108 bits (271), Expect = 8e-24
 Identities = 60/138 (43%), Positives = 85/138 (61%), Gaps = 2/138 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           V++ DV G  E   ++RE V+  L  PERF+ LG + PKG LL GPPG GKTL A+AVA 
Sbjct: 172 VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVAN 231

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
                F+ + G E V+   G GA  VR LF+ AR +  C+++ DEIDA+G  R    +G 
Sbjct: 232 RTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGG 291

Query: 425 SNTEEEQTLNQLLVEMDG 442
            N E ++T+ +L+ ++DG
Sbjct: 292 DN-EVQRTMLELINQLDG 308


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  106 bits (264), Expect = 5e-23
 Identities = 57/170 (33%), Positives = 101/170 (59%), Gaps = 4/170 (2%)

Query: 286 AFNQLKMARFTIVDGKMG-KGVSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPK 343
           AF  ++ + F  V G M  K V ++++ G+ + KL++++ +++ LK P  F+++G   PK
Sbjct: 440 AFKNIQPSSFRSVIGLMDIKPVDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPK 499

Query: 344 GALLLGPPGCGKTLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPC 403
           G LL GPPGC KT L +A+AT     F++++G +      G     +  +F++ARA  P 
Sbjct: 500 GVLLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPA 559

Query: 404 IVYIDEIDAVGKKRSTTMSGFSNTEEEQTLNQLLVEMDGASLDQLPSQGT 453
           I+++DEID++   RS + +G     +E+ L+ LL E+DG  L  +  +G+
Sbjct: 560 ILFLDEIDSILGARSASKTGCD--VQERVLSVLLNELDGVGLKTIERRGS 607



 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 52/141 (36%), Positives = 76/141 (53%), Gaps = 10/141 (7%)

Query: 311 VAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATEAQVP 369
           + G+ EA   +RE +   L+ P     LG  VP+G LL GPPG GKT L +AVA EA   
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261

Query: 370 FLAMAGPEFVEVIGGLGAARVRSLFKEAR---ARAPCIVYIDEIDAVGKKRSTTMSGFSN 426
            LA++ P       G     VR +F+ AR   +R P ++++DE+DA+  +R       S 
Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQRG------SR 315

Query: 427 TEEEQTLNQLLVEMDGASLDQ 447
             E + + Q+L  +DGAS D+
Sbjct: 316 APESRVVAQVLTLLDGASGDR 336


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  105 bits (261), Expect = 1e-22
 Identities = 57/138 (41%), Positives = 87/138 (63%), Gaps = 2/138 (1%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364
           VS+ ++ G+ E   E+RE ++  L +PE F ++G   PKG LL GPPG GKTLLA+AVA+
Sbjct: 144 VSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVAS 203

Query: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424
           +    FL +     V+   G  A  +R +F  AR   PCI+++DEIDA+G +R +  +  
Sbjct: 204 QLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTS- 262

Query: 425 SNTEEEQTLNQLLVEMDG 442
           ++ E ++TL +LL +MDG
Sbjct: 263 ADREIQRTLMELLNQMDG 280


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  104 bits (259), Expect = 2e-22
 Identities = 57/137 (41%), Positives = 86/137 (62%), Gaps = 2/137 (1%)

Query: 307 SFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           +++ + G+ +   E++E ++  +K PE F  LG   PKG LL GPPG GKTLLA+AVA  
Sbjct: 147 TYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAVAHH 206

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
               F+ ++G E V+   G GA  VR LF  AR  AP I+++DEID++G  R    SG  
Sbjct: 207 TDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGSG-G 265

Query: 426 NTEEEQTLNQLLVEMDG 442
           ++E ++T+ +LL ++DG
Sbjct: 266 DSEVQRTMLELLNQLDG 282


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  103 bits (257), Expect = 4e-22
 Identities = 55/139 (39%), Positives = 88/139 (63%), Gaps = 8/139 (5%)

Query: 308 FKDVAGMHEAKLEVREFVDYLKSP----ERFLQLGAKVPKGALLLGPPGCGKTLLAKAVA 363
           + D+ G+ +   +++E V+ +  P    E+F  LG + PKG L+ GPPG GKTLLA+A A
Sbjct: 185 YSDIGGLDK---QIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACA 241

Query: 364 TEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSG 423
            + +  FL +AGP+ V++  G GA  VR  F  A+ +AP I++IDE+DA+G KR  +   
Sbjct: 242 AQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKA 301

Query: 424 FSNTEEEQTLNQLLVEMDG 442
             + E ++T+ +LL ++DG
Sbjct: 302 -GDREVQRTMLELLNQLDG 319


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 89.0 bits (219), Expect = 9e-18
 Identities = 46/140 (32%), Positives = 79/140 (56%), Gaps = 5/140 (3%)

Query: 304 KGVSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAV 362
           + + +  + G+HE +  + + +    K PE F  L  +   G LL GPPG GKTLLA  +
Sbjct: 835 RDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVI 894

Query: 363 ATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMS 422
           A E+++ F+++ GPE +    G     VR +F  A+A  PCI++ DE +++  +R    +
Sbjct: 895 ARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNT 954

Query: 423 GFSNTEEEQTLNQLLVEMDG 442
           G +    ++ +NQLL ++DG
Sbjct: 955 GVT----DRVVNQLLTQLDG 970



 Score = 33.5 bits (75), Expect = 0.45
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 15/91 (16%)

Query: 333 RFLQLGAKVPKGALLL-GPPGCGKTLLAKAVATEA---------QVPFLAMAGPEFVEVI 382
           + + L A +  GALLL G  G GK+ LAKA+  EA         +V   A+ G     + 
Sbjct: 582 QLMSLVAGLRNGALLLTGGKGSGKSTLAKAICKEAFDKLDAHVERVDCKALRGKRLENIQ 641

Query: 383 GGLGAARVRSLFKEARARAPCIVYIDEIDAV 413
             L  A     F EA    P +V +D++D +
Sbjct: 642 KTLEVA-----FSEAVWMQPSVVLLDDLDLI 667


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score = 85.9 bits (211), Expect = 8e-17
 Identities = 60/143 (41%), Positives = 80/143 (55%), Gaps = 13/143 (9%)

Query: 306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQL--GAKVP-KGALLLGPPGCGKTLLAKAV 362
           + + D+ G+  AK  V+E V Y   P R+ QL  G   P KG LL GPPG GKTLLAKAV
Sbjct: 179 IKWNDIIGLDAAKQLVKEAVVY---PIRYPQLFTGILSPWKGLLLYGPPGTGKTLLAKAV 235

Query: 363 ATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMS 422
           ATE +  F  ++    V    G     VR LF+ AR  AP  +++DE+++V  +R T   
Sbjct: 236 ATECKTTFFNISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQRGTASG 295

Query: 423 GFSNTEEEQTL---NQLLVEMDG 442
           G    E E +L    +LLV+MDG
Sbjct: 296 G----EHEGSLRMKTELLVQMDG 314


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 48/143 (33%), Positives = 80/143 (55%), Gaps = 6/143 (4%)

Query: 303 GKGVSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKA 361
           G  V+++D+AG+  AK  ++E V + +  P+ F  L    PKG LL GPPG GKTL+ K 
Sbjct: 395 GPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKC 453

Query: 362 VATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTM 421
           +A+++   F +++         G G   VR+LF  AR + P +++IDEID++  +R    
Sbjct: 454 IASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG- 512

Query: 422 SGFSNTEEEQTLNQLLVEMDGAS 444
               +    +   + LV++DGA+
Sbjct: 513 ---EHESSRRIKTEFLVQLDGAT 532


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score = 83.6 bits (205), Expect = 4e-16
 Identities = 48/143 (33%), Positives = 80/143 (55%), Gaps = 6/143 (4%)

Query: 303 GKGVSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKA 361
           G  V+++D+AG+  AK  ++E V + +  P+ F  L    PKG LL GPPG GKTL+ K 
Sbjct: 395 GPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLRGP-PKGILLFGPPGTGKTLIGKC 453

Query: 362 VATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTM 421
           +A+++   F +++         G G   VR+LF  AR + P +++IDEID++  +R    
Sbjct: 454 IASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVIFIDEIDSLLSQRGDG- 512

Query: 422 SGFSNTEEEQTLNQLLVEMDGAS 444
               +    +   + LV++DGA+
Sbjct: 513 ---EHESSRRIKTEFLVQLDGAT 532


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 54/139 (38%), Positives = 78/139 (56%), Gaps = 7/139 (5%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVP-KGALLLGPPGCGKTLLAKAVA 363
           V + D+A + EAK  ++E V   +  PE F   G + P KG L++GPPG GKTLLAKAVA
Sbjct: 206 VRWDDIADLVEAKKLLKEAVVLPMWMPEFFK--GIRRPWKGVLMVGPPGTGKTLLAKAVA 263

Query: 364 TEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSG 423
           TE +  F  ++         G     VR LF+ AR  +P  ++IDEID++  +R T+   
Sbjct: 264 TECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTSE-- 321

Query: 424 FSNTEEEQTLNQLLVEMDG 442
             +    +   +LLV+MDG
Sbjct: 322 -EHEASRRVKAELLVQMDG 339


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 49/137 (35%), Positives = 74/137 (54%), Gaps = 3/137 (2%)

Query: 306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           + + D+A + EAK  +RE V        F +   +  KG L++GPPG GKT+LAKAVATE
Sbjct: 205 IHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATE 264

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
               F  ++         G     VR LF+ AR  AP  ++IDEID++  +R T+     
Sbjct: 265 CGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTS---DE 321

Query: 426 NTEEEQTLNQLLVEMDG 442
           +    +  ++LL++MDG
Sbjct: 322 HEASRRVKSELLIQMDG 338


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 80.1 bits (196), Expect = 4e-15
 Identities = 49/137 (35%), Positives = 74/137 (54%), Gaps = 3/137 (2%)

Query: 306 VSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365
           + + D+A + EAK  +RE V        F +   +  KG L++GPPG GKT+LAKAVATE
Sbjct: 205 IHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATE 264

Query: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425
               F  ++         G     VR LF+ AR  AP  ++IDEID++  +R T+     
Sbjct: 265 CGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTS---DE 321

Query: 426 NTEEEQTLNQLLVEMDG 442
           +    +  ++LL++MDG
Sbjct: 322 HEASRRVKSELLIQMDG 338


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/147 (37%), Positives = 75/147 (51%), Gaps = 8/147 (5%)

Query: 297 IVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVP-KGALLLGPPGCGK 355
           IVD   G  V F D+AG   AK  ++E V  L S    L  G + P +G LL GPPG GK
Sbjct: 300 IVDN--GTAVKFDDIAGQDLAKQALQEIV-ILPSLRPELFTGLRAPARGLLLFGPPGNGK 356

Query: 356 TLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGK 415
           T+LAKAVA E+   F  ++         G G   VR+LF  AR   P I++IDE+D++  
Sbjct: 357 TMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLC 416

Query: 416 KRSTTMSGFSNTEEEQTLNQLLVEMDG 442
           +R        +    +   + L+E DG
Sbjct: 417 ERREG----EHDASRRLKTEFLIEFDG 439


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 55/147 (37%), Positives = 75/147 (51%), Gaps = 8/147 (5%)

Query: 297 IVDGKMGKGVSFKDVAGMHEAKLEVREFVDYLKSPERFLQLGAKVP-KGALLLGPPGCGK 355
           IVD   G  V F D+AG   AK  ++E V  L S    L  G + P +G LL GPPG GK
Sbjct: 332 IVDN--GTAVKFDDIAGQDLAKQALQEIV-ILPSLRPELFTGLRAPARGLLLFGPPGNGK 388

Query: 356 TLLAKAVATEAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGK 415
           T+LAKAVA E+   F  ++         G G   VR+LF  AR   P I++IDE+D++  
Sbjct: 389 TMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLC 448

Query: 416 KRSTTMSGFSNTEEEQTLNQLLVEMDG 442
           +R        +    +   + L+E DG
Sbjct: 449 ERREG----EHDASRRLKTEFLIEFDG 471


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 55/144 (38%), Positives = 78/144 (54%), Gaps = 9/144 (6%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVP-KGALLLGPPGCGKTLLAKAVA 363
           V + DVAG+  AK  ++E V   +K P  F   G + P +G LL GPPG GK+ LAKAVA
Sbjct: 131 VKWSDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYLAKAVA 188

Query: 364 TEA-QVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMS 422
           TEA    F +++  + V    G     V++LF+ AR   P I++IDEID++   RS   S
Sbjct: 189 TEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSENES 248

Query: 423 GFSNTEEEQTLNQLLVEMDGASLD 446
                   +   + LV+M G  +D
Sbjct: 249 ----EAARRIKTEFLVQMQGVGVD 268


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score = 70.5 bits (171), Expect = 3e-12
 Identities = 50/140 (35%), Positives = 76/140 (54%), Gaps = 9/140 (6%)

Query: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVP-KGALLLGPPGCGKTLLAKAVA 363
           + + DVAG+  AK  ++E V   +K P  F   G + P +G LL GPPG GK+ LAKAVA
Sbjct: 124 IRWNDVAGLEGAKEALKEAVILPIKFPHLFT--GKRTPWRGILLFGPPGTGKSYLAKAVA 181

Query: 364 TEA-QVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMS 422
           TEA    F +++  + +    G     V++LF+ AR   P I++IDE+D++   R+   S
Sbjct: 182 TEANNSTFFSVSSSDLMSKWLGESEKLVKNLFELARQHKPSIIFIDEVDSLCGSRNENES 241

Query: 423 GFSNTEEEQTLNQLLVEMDG 442
                   +   + LV+M G
Sbjct: 242 ----EAARRIKTEFLVQMQG 257


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.138    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,259,727
Number of Sequences: 37866
Number of extensions: 1043035
Number of successful extensions: 11135
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 124
Number of HSP's that attempted gapping in prelim test: 8594
Number of HSP's gapped (non-prelim): 2393
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.